format-version: 1.2 date: 11:04:2009 03:11 auto-generated-by: ONTO-PERL subsetdef: goslim_candida "Candida GO slim" subsetdef: goslim_generic "Generic GO slim" subsetdef: goslim_goa "GOA and proteome slim" subsetdef: goslim_pir "PIR GO slim" subsetdef: goslim_plant "Plant GO slim" subsetdef: goslim_yeast "Yeast GO slim" subsetdef: gosubset_prok "Prokaryotic GO subset" subsetdef: Drugable "Drugable Genome Project" subsetdef: PSI-MI slim "Subset of PSI-MI" synonymtypedef: systematic_synonym "Systematic synonym" EXACT synonymtypedef: PSI-MI-alternate "Alternate label curated by PSI-MI" EXACT synonymtypedef: PSI-MI-short "Unique short label curated by PSI-MI" EXACT default-namespace: cellcycle_ontology remark: Merged ontology [Term] id: CCO:B0000000 name: core cell cycle protein def: "A protein being considered as principal in the regulation of the cell cycle process" [CCO:cco_team] is_a: CCO:U0000007 ! cell cycle protein [Term] id: CCO:B0001317 name: E2F8_HUMAN def: "Transcription factor E2F8" [UniProtKB:A0AVK6] synonym: "E2F-8" EXACT [UniProtKB:A0AVK6] xref: EMBL:AAH28244.1 xref: EMBL:AAH90877.1 xref: EMBL:AAI08701.1 xref: EMBL:AAI26401.1 xref: EMBL:AAI26403.1 xref: EMBL:BAB15605.1 xref: EMBL:BAE46901.1 xref: UniProtKB:A0AVK6 xref: UniProtKB:Q2VPJ3 xref: UniProtKB:Q3C1U6 xref: UniProtKB:Q5BKY4 xref: UniProtKB:Q8N340 xref: UniProtKB:Q9H5M0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004540 ! E2F8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0048246 ! E2F8_HUMAN-Phosphoserine357 [Term] id: CCO:B0001318 name: A4D1Y2_HUMAN def: "Similar to cell division cycle 10 homolog" [UniProtKB:A4D1Y2] xref: EMBL:EAL23974.1 xref: UniProtKB:A4D1Y2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005978 ! LOC392884_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001319 name: A6NC65_HUMAN def: "Septin" [UniProtKB:A6NC65] xref: UniProtKB:A6NC65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005591 ! SEPT8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001321 name: A6NE16_HUMAN def: "Uncharacterized protein ENSP00000330459" [UniProtKB:A6NE16] xref: UniProtKB:A6NE16 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001324 name: A6NFQ9_HUMAN def: "Septin" [UniProtKB:A6NFQ9] xref: UniProtKB:A6NFQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005591 ! SEPT8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001328 name: A6NHZ8_HUMAN def: "Uncharacterized protein ENSP00000368241" [UniProtKB:A6NHZ8] xref: UniProtKB:A6NHZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001333 name: A6NK88_HUMAN def: "Putative uncharacterized protein CDKN1C" [UniProtKB:A6NK88] xref: UniProtKB:A6NK88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004311 ! CDKN1C_human relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001334 name: SAC31_HUMAN def: "SAC3 domain-containing protein 1" [UniProtKB:A6NKF1] synonym: "SAC3 homology domain-containing protein 1" EXACT [UniProtKB:A6NKF1] xref: UniProtKB:A6NKF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005558 ! SAC3D1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013954 ! SAC31_HUMAN-Phosphoserine401 [Term] id: CCO:B0001335 name: A6NKP6_HUMAN def: "Septin" [UniProtKB:A6NKP6] xref: UniProtKB:A6NKP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005591 ! SEPT8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001337 name: A6NLT8_HUMAN def: "Putative uncharacterized protein SPO11" [UniProtKB:A6NLT8] xref: UniProtKB:A6NLT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005664 ! SPO11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0001339 name: A6NMH6_HUMAN def: "Septin" [UniProtKB:A6NMH6] xref: UniProtKB:A6NMH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005591 ! SEPT8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001340 name: A6NMK2_HUMAN def: "Putative uncharacterized protein HORMAD1" [UniProtKB:A6NMK2] xref: UniProtKB:A6NMK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004824 ! HORMAD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001341 name: A6NMP7_HUMAN def: "Putative uncharacterized protein MAD2L1BP" [UniProtKB:A6NMP7] xref: UniProtKB:A6NMP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005047 ! MAD2L1BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis [Term] id: CCO:B0001343 name: A7KMP4_HUMAN def: "Truncated cyclin-dependent kinase inhibitor 1B" [UniProtKB:A7KMP4] xref: EMBL:ABS17636.1 xref: UniProtKB:A7KMP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004310 ! CDKN1B_human relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001344 name: APBB1_HUMAN def: "Amyloid beta A4 precursor protein-binding family B member 1" [UniProtKB:O00213] synonym: "Fe65 protein" EXACT [UniProtKB:O00213] xref: EMBL:AAB93631.1 xref: EMBL:AAC79942.1 xref: EMBL:AAH10854.1 xref: EMBL:EAW68723.1 xref: UniProtKB:A6NH82 xref: UniProtKB:A6NL69 xref: UniProtKB:O00213 xref: UniProtKB:Q96A93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004076 ! APBB1_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0006279 ! app-apbb1-2 physical interaction relationship: participates_in CCO:I0007060 ! apbb1-aplp2-1 physical interaction relationship: participates_in CCO:I0007061 ! apbb1-app physical interaction relationship: participates_in CCO:I0007411 ! app-apbb1-6 physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0007620 ! atxn1-apbb1 physical interaction relationship: participates_in CCO:I0007621 ! atxn1-apbb1-1 physical interaction relationship: participates_in CCO:I0007727 ! app-apbb1-5 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0001345 name: SPT5H_HUMAN def: "Transcription elongation factor SPT5" [UniProtKB:O00267] synonym: "DRB sensitivity-inducing factor large subunit" EXACT [UniProtKB:O00267] synonym: "DSIF large subunit" EXACT [UniProtKB:O00267] synonym: "DSIF p160" EXACT [UniProtKB:O00267] synonym: "hSPT5" EXACT [UniProtKB:O00267] synonym: "Tat-cotransactivator 1 protein" EXACT [UniProtKB:O00267] synonym: "Tat-CT1 protein" EXACT [UniProtKB:O00267] xref: EMBL:AAC51102.1 xref: EMBL:AAD02179.1 xref: EMBL:AAH24203.1 xref: EMBL:BAA24075.1 xref: EMBL:BAD92494.1 xref: EMBL:CAA73326.1 xref: UniProtKB:O00267 xref: UniProtKB:O43279 xref: UniProtKB:Q59G52 xref: UniProtKB:Q99639 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005666 ! SUPT5H_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007885 ! supt5h-ppia-1 physical interaction relationship: participates_in CCO:I0008056 ! supt5h-med31 physical interaction relationship: participates_in CCO:I0008170 ! supt5h-kiaa1377 physical interaction relationship: participates_in CCO:I0008171 ! supt5h-rpl8 physical interaction relationship: participates_in CCO:I0008327 ! supt5h-c9orf78 physical interaction relationship: participates_in CCO:I0008328 ! supt5h-gtf3c1 physical interaction relationship: participates_in CCO:I0008329 ! supt5h-ik physical interaction relationship: participates_in CCO:I0008330 ! supt5h-loc56902 physical interaction relationship: participates_in CCO:I0008331 ! supt5h-phyhip physical interaction relationship: participates_in CCO:I0008332 ! supt5h-ppia physical interaction relationship: participates_in CCO:I0008434 ! supt5h-dbn1 physical interaction relationship: participates_in CCO:I0008508 ! supt5h-h2afx physical interaction relationship: participates_in CCO:I0008509 ! supt5h-iqwd1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0014178 ! SPT5H_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0014179 ! SPT5H_HUMAN-dimethylarginine681 relationship: transforms_into CCO:B0014180 ! SPT5H_HUMAN-Omega-N-methylarginine681 relationship: transforms_into CCO:B0014181 ! SPT5H_HUMAN-dimethylarginine696 relationship: transforms_into CCO:B0014182 ! SPT5H_HUMAN-Omega-N-methylarginine696 relationship: transforms_into CCO:B0014183 ! SPT5H_HUMAN-dimethylarginine698 relationship: transforms_into CCO:B0014184 ! SPT5H_HUMAN-Omega-N-methylarginine698 relationship: transforms_into CCO:B0014185 ! SPT5H_HUMAN-Phosphothreonine709 relationship: transforms_into CCO:B0014186 ! SPT5H_HUMAN-Phosphotyrosine717 relationship: transforms_into CCO:B0014187 ! SPT5H_HUMAN-Phosphothreonine775 relationship: transforms_into CCO:B0014188 ! SPT5H_HUMAN-Phosphothreonine784 relationship: transforms_into CCO:B0014189 ! SPT5H_HUMAN-Phosphothreonine1034 [Term] id: CCO:B0001346 name: CDC7_HUMAN def: "Cell division cycle 7-related protein kinase" [UniProtKB:O00311] synonym: "CDC7-related kinase" EXACT [UniProtKB:O00311] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O00311] synonym: "HsCdc7" EXACT [UniProtKB:O00311] synonym: "huCdc7" EXACT [UniProtKB:O00311] xref: EMBL:AAB97512.1 xref: EMBL:AAC52080.1 xref: EMBL:AAI10527.1 xref: EMBL:AAI10528.1 xref: EMBL:AAI11045.1 xref: EMBL:AAS79323.1 xref: EMBL:BAA19962.1 xref: EMBL:CAI14446.1 xref: UniProtKB:O00311 xref: UniProtKB:O00558 xref: UniProtKB:Q5T5U5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004294 ! CDC7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006090 ! orc6l-cdc7 direct interaction relationship: participates_in CCO:I0006092 ! mcm10-cdc7 direct interaction relationship: participates_in CCO:I0006137 ! cdkn1a-cdc7 direct interaction relationship: participates_in CCO:I0006138 ! cdc7-orc5l direct interaction relationship: participates_in CCO:I0006141 ! cdkn2a-cdc7 direct interaction relationship: participates_in CCO:I0006146 ! mcm3-cdc7 direct interaction relationship: participates_in CCO:I0006162 ! cdc7-cdk4 direct interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000215 ! regulation of S phase relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001347 name: FOXN3_HUMAN def: "Forkhead box protein N3" [UniProtKB:O00409] synonym: "Checkpoint suppressor 1" EXACT [UniProtKB:O00409] xref: EMBL:AAB58252.1 xref: EMBL:AAF18259.1 xref: EMBL:AAH07506.1 xref: UniProtKB:O00409 xref: UniProtKB:Q96II7 xref: UniProtKB:Q9UIE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004655 ! FOXN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006483 ! exosc8-ches1 physical interaction relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000015 ! G2 phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011889 ! FOXN3_HUMAN-Phosphoserine85 [Term] id: CCO:B0001348 name: PLK4_HUMAN def: "Serine/threonine-protein kinase PLK4" [UniProtKB:O00444] synonym: "EC 2.7.11.21" EXACT [UniProtKB:O00444] synonym: "PLK-4" EXACT [UniProtKB:O00444] synonym: "Polo-like kinase 4" EXACT [UniProtKB:O00444] synonym: "Serine/threonine-protein kinase 18" EXACT [UniProtKB:O00444] synonym: "Serine/threonine-protein kinase Sak" EXACT [UniProtKB:O00444] xref: EMBL:AAH36023.1 xref: EMBL:BAB69958.1 xref: EMBL:CAA73575.1 xref: UniProtKB:O00444 xref: UniProtKB:Q8IYF0 xref: UniProtKB:Q96Q95 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005340 ! PLK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005787 ! plk4-sfn physical interaction relationship: participates_in CCO:I0007888 ! plk4-sfn-1 physical interaction [Term] id: CCO:B0001349 name: BIN1_HUMAN def: "Myc box-dependent-interacting protein 1" [UniProtKB:O00499] synonym: "Amphiphysin II" EXACT [UniProtKB:O00499] synonym: "Amphiphysin-like protein" EXACT [UniProtKB:O00499] synonym: "Box-dependent myc-interacting protein 1" EXACT [UniProtKB:O00499] synonym: "Bridging integrator 1" EXACT [UniProtKB:O00499] xref: EMBL:AAB61363.1 xref: EMBL:AAB63263.1 xref: EMBL:AAC17461.1 xref: EMBL:AAC23440.1 xref: EMBL:AAC23441.1 xref: EMBL:AAC23750.1 xref: EMBL:AAC23751.1 xref: EMBL:AAC24126.1 xref: EMBL:AAC24127.1 xref: EMBL:AAC24128.1 xref: EMBL:AAC28646.1 xref: EMBL:AAC39710.1 xref: EMBL:AAC39711.1 xref: EMBL:AAC39712.1 xref: EMBL:AAC39713.1 xref: EMBL:AAC51345.1 xref: UniProtKB:O00297 xref: UniProtKB:O00499 xref: UniProtKB:O00545 xref: UniProtKB:O43867 xref: UniProtKB:O60552 xref: UniProtKB:O60553 xref: UniProtKB:O60554 xref: UniProtKB:O60555 xref: UniProtKB:O75514 xref: UniProtKB:O75515 xref: UniProtKB:O75516 xref: UniProtKB:O75517 xref: UniProtKB:O75518 xref: UniProtKB:Q92944 xref: UniProtKB:Q99688 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004163 ! BIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008379 ! cutl1-bin1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001243 ! regulation of endocytosis relationship: transforms_into CCO:B0010794 ! BIN1_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0010795 ! BIN1_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0010796 ! BIN1_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0010797 ! BIN1_HUMAN-Phosphothreonine307 relationship: transforms_into CCO:B0010798 ! BIN1_HUMAN-Phosphoserine331 [Term] id: CCO:B0001350 name: LHR2A_HUMAN def: "Loss of heterozygosity 11 chromosomal region 2 gene A protein" [UniProtKB:O00534] synonym: "BCSC-1" EXACT [UniProtKB:O00534] synonym: "Breast cancer suppressor candidate 1" EXACT [UniProtKB:O00534] xref: EMBL:AAB60942.1 xref: EMBL:AAH01234.1 xref: EMBL:AAP35301.1 xref: EMBL:AAQ94867.1 xref: EMBL:AAQ94868.1 xref: EMBL:AAQ94869.1 xref: EMBL:AAQ94871.1 xref: EMBL:AAQ94872.1 xref: EMBL:AAQ94873.1 xref: EMBL:AAQ94874.1 xref: EMBL:AAQ94875.1 xref: EMBL:AAQ94876.1 xref: UniProtKB:O00534 xref: UniProtKB:Q6UN19 xref: UniProtKB:Q6UN20 xref: UniProtKB:Q9BVF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004979 ! LOH11CR2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001351 name: PESC_HUMAN def: "Pescadillo homolog 1" [UniProtKB:O00541] xref: EMBL:AAB61140.1 xref: EMBL:AAH32489.1 xref: EMBL:CAG30425.1 xref: UniProtKB:O00541 xref: UniProtKB:Q6IC29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005298 ! PES1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000019 ! mitotic metaphase relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0069236 ! PESC_HUMAN-Phosphotyrosine548 [Term] id: CCO:B0001352 name: E2F3_HUMAN def: "Transcription factor E2F3" [UniProtKB:O00716] synonym: "E2F-3" EXACT [UniProtKB:O00716] xref: EMBL:AAN17846.1 xref: EMBL:BAA07553.1 xref: EMBL:CAA71504.1 xref: EMBL:CAC28598.2 xref: EMBL:CAI21471.1 xref: UniProtKB:O00716 xref: UniProtKB:Q15000 xref: UniProtKB:Q9BZ44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004535 ! E2F3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001353 name: PPP6_HUMAN def: "Serine/threonine-protein phosphatase 6" [UniProtKB:O00743] synonym: "EC 3.1.3.16" EXACT [UniProtKB:O00743] synonym: "PP6" EXACT [UniProtKB:O00743] xref: EMBL:AAD45400.2 xref: EMBL:AAH06990.1 xref: EMBL:AAV38514.1 xref: EMBL:CAA63549.1 xref: EMBL:CAI13677.1 xref: EMBL:EAW87611.1 xref: UniProtKB:O00743 xref: UniProtKB:Q5U0A2 xref: UniProtKB:Q9UIC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005370 ! PPP6C_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006429 ! nfkbie-ppp6c physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001354 name: UBE2C_HUMAN def: "Ubiquitin-conjugating enzyme E2 C" [UniProtKB:O00762] synonym: "EC 6.3.2.19" EXACT [UniProtKB:O00762] synonym: "UbcH10" EXACT [UniProtKB:O00762] synonym: "Ubiquitin carrier protein C" EXACT [UniProtKB:O00762] synonym: "Ubiquitin-protein ligase C" EXACT [UniProtKB:O00762] xref: EMBL:AAB53362.1 xref: EMBL:AAH07656.1 xref: EMBL:AAH16292.1 xref: EMBL:AAH50736.1 xref: EMBL:AAP35964.1 xref: EMBL:CAB66118.1 xref: UniProtKB:O00762 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005860 ! UBE2C_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008386 ! eno2-ube2c physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000141 ! cyclin catabolic process relationship: participates_in CCO:P0000177 ! positive regulation of exit from mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001355 name: CDKA1_HUMAN def: "Cyclin-dependent kinase 2-associated protein 1" [UniProtKB:O14519] synonym: "CDK2-associated protein 1" EXACT [UniProtKB:O14519] synonym: "Deleted in oral cancer 1" EXACT [UniProtKB:O14519] synonym: "DOC-1" EXACT [UniProtKB:O14519] synonym: "Putative oral cancer suppressor" EXACT [UniProtKB:O14519] xref: EMBL:AAC77831.1 xref: EMBL:AAH34717.1 xref: EMBL:BAA22937.1 xref: UniProtKB:O14519 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004307 ! CDK2AP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000014 ! S phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:B0001356 name: CTRO_HUMAN def: "Citron Rho-interacting kinase" [UniProtKB:O14578] synonym: "CRIK" EXACT [UniProtKB:O14578] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O14578] synonym: "Rho-interacting, serine/threonine-protein kinase 21" EXACT [UniProtKB:O14578] xref: EMBL:AAB71327.1 xref: EMBL:AAP13528.1 xref: EMBL:AAP43922.1 xref: EMBL:BAA76793.2 xref: UniProtKB:O14578 xref: UniProtKB:Q6XUH8 xref: UniProtKB:Q86UQ9 xref: UniProtKB:Q9UPZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004420 ! CIT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011406 ! CTRO_HUMAN-Phosphoserine440 relationship: transforms_into CCO:B0011407 ! CTRO_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0011408 ! CTRO_HUMAN-Phosphoserine1582 relationship: transforms_into CCO:B0011409 ! CTRO_HUMAN-Phosphoserine1971 relationship: transforms_into CCO:B0011410 ! CTRO_HUMAN-Phosphoserine1993 relationship: transforms_into CCO:B0031308 ! CTRO_HUMAN-Phosphotyrosine1196 relationship: transforms_into CCO:B0031309 ! CTRO_HUMAN-Phosphotyrosine1478 [Term] id: CCO:B0001357 name: ANM5_HUMAN def: "Protein arginine N-methyltransferase 5" [UniProtKB:O14744] synonym: "72 kDa ICln-binding protein" EXACT [UniProtKB:O14744] synonym: "EC 2.1.1.-" EXACT [UniProtKB:O14744] synonym: "EC 2.1.1.125" EXACT [UniProtKB:O14744] synonym: "Jak-binding protein 1" EXACT [UniProtKB:O14744] synonym: "Shk1 kinase-binding protein 1 homolog" EXACT [UniProtKB:O14744] synonym: "SKB1Hs" EXACT [UniProtKB:O14744] xref: EMBL:AAB66581.1 xref: EMBL:AAF04502.1 xref: EMBL:AAH25979.1 xref: EMBL:CAG33022.1 xref: UniProtKB:O14744 xref: UniProtKB:Q6IBR1 xref: UniProtKB:Q9UKH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004065 ! PRMT5_human relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001930 ! histone-arginine N-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008416 ! phyhip-skb1 physical interaction relationship: participates_in CCO:I0008421 ! ptd004-skb1 physical interaction relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0041110 ! ANM5_HUMAN-N-acetylalanine2 [Term] id: CCO:B0001358 name: OVOL1_HUMAN def: "Putative transcription factor Ovo-like 1" [UniProtKB:O14753] synonym: "hOvo1" EXACT [UniProtKB:O14753] xref: EMBL:AAB72084.1 xref: EMBL:AAH59408.1 xref: EMBL:CAH56127.1 xref: UniProtKB:O14753 xref: UniProtKB:Q6PCB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005240 ! OVOL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000035 ! pachytene relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001359 name: CHK1_HUMAN def: "Serine/threonine-protein kinase Chk1" [UniProtKB:O14757] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O14757] xref: EMBL:AAB88852.1 xref: EMBL:AAC51736.1 xref: EMBL:AAH04202.1 xref: EMBL:AAH17575.1 xref: EMBL:AAM78553.1 xref: EMBL:BAA84577.1 xref: UniProtKB:O14757 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004347 ! CHEK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006255 ! chek1-aatf phosphorylation relationship: participates_in CCO:I0007377 ! cdc25c-chek1-1 phosphorylation relationship: participates_in CCO:I0007800 ! hspcb-chk1-1 physical interaction relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0011212 ! CHK1_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0011213 ! CHK1_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0011214 ! CHK1_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0011215 ! CHK1_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0011216 ! CHK1_HUMAN-Phosphoserine345 [Term] id: CCO:B0001360 name: NDC80_HUMAN def: "Kinetochore protein NDC80 homolog" [UniProtKB:O14777] synonym: "Highly expressed in cancer protein" EXACT [UniProtKB:O14777] synonym: "HsHec1" EXACT [UniProtKB:O14777] synonym: "Kinetochore protein Hec1" EXACT [UniProtKB:O14777] synonym: "Kinetochore-associated protein 2" EXACT [UniProtKB:O14777] synonym: "Retinoblastoma-associated protein HEC" EXACT [UniProtKB:O14777] xref: EMBL:AAB80726.1 xref: UniProtKB:O14777 xref: UniProtKB:Q6PJX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006415 ! NDC80_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005764 ! kntc2-pldn physical interaction relationship: participates_in CCO:I0005899 ! kntc2-ushbp1 physical interaction relationship: participates_in CCO:I0005911 ! amotl2-kntc2 physical interaction relationship: participates_in CCO:I0006064 ! kntc2-spbc25-1 physical interaction relationship: participates_in CCO:I0006065 ! kntc2-spbc25-2 physical interaction relationship: participates_in CCO:I0006066 ! kntc2_zwint_5 physical interaction relationship: participates_in CCO:I0006226 ! kntc2_cenpb_1 colocalization relationship: participates_in CCO:I0006446 ! kntc2_zwint_6 colocalization relationship: participates_in CCO:I0006755 ! kntc2_zwint_4 colocalization relationship: participates_in CCO:I0006757 ! kntc2_zw10_2 colocalization relationship: participates_in CCO:I0006764 ! kntc2-spbc24-3 physical interaction relationship: participates_in CCO:I0006765 ! kntc2-spbc25-4 physical interaction relationship: participates_in CCO:I0006791 ! kntc2_zwint_1 physical interaction relationship: participates_in CCO:I0006908 ! kntc2-spbc25-3 physical interaction relationship: participates_in CCO:I0006909 ! cenph_kntc2_2 physical interaction relationship: participates_in CCO:I0006910 ! cenph_kntc2_4 physical interaction relationship: participates_in CCO:I0007156 ! kntc2-cdca1-4 physical interaction relationship: participates_in CCO:I0007157 ! kntc2_zwint_2 physical interaction relationship: participates_in CCO:I0007158 ! zwint_kntc2_2 physical interaction relationship: participates_in CCO:I0007159 ! kntc2_zwint_3 physical interaction relationship: participates_in CCO:I0007160 ! zw10_kntc2_1 physical interaction relationship: participates_in CCO:I0007161 ! zwint_kntc2_3 physical interaction relationship: participates_in CCO:I0007162 ! zw10_kntc2_2 physical interaction relationship: participates_in CCO:I0007169 ! kntc2-spbc24-4 physical interaction relationship: participates_in CCO:I0007301 ! kntc2-spbc24-1 physical interaction relationship: participates_in CCO:I0007303 ! kntc2-cdca1-3 physical interaction relationship: participates_in CCO:I0007318 ! cdca1-kntc2 physical interaction relationship: participates_in CCO:I0007456 ! cenph_kntc2_1 physical interaction relationship: participates_in CCO:I0007463 ! kntc2-cdca1-2 physical interaction relationship: participates_in CCO:I0007473 ! kntc2-cdca1-1 physical interaction relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: participates_in CCO:I0007932 ! kntc2-spbc24-2 physical interaction relationship: participates_in CCO:I0008258 ! kntc2-tom1l1 physical interaction relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0031343 ! NDC80_HUMAN-Phosphoserine55 relationship: transforms_into CCO:B0031344 ! NDC80_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0031345 ! NDC80_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0031346 ! NDC80_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0031347 ! NDC80_HUMAN-Phosphoserine165 [Term] id: CCO:B0001361 name: O14835_HUMAN def: "Dim1p homolog" [UniProtKB:O14835] synonym: "Thioredoxin-like 4A, isoform CRA_a" EXACT [UniProtKB:O14835] xref: EMBL:AAB81951.1 xref: EMBL:EAW66639.1 xref: UniProtKB:O14835 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005847 ! TXNL4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001362 name: EREG_HUMAN def: "Proepiregulin precursor" [UniProtKB:O14944] xref: EMBL:BAA22146.1 xref: EMBL:CAG46685.1 xref: UniProtKB:O14944 xref: UniProtKB:Q6FH69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004581 ! EREG_human relationship: has_function CCO:F0001456 ! epidermal growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000134 ! female meiosis relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002044 ! positive regulation of cytokine biosynthetic process relationship: participates_in CCO:P0002059 ! positive regulation of phosphorylation relationship: participates_in CCO:P0002248 ! keratinocyte proliferation relationship: participates_in CCO:P0002351 ! positive regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002529 ! positive regulation of epidermal growth factor receptor activity relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: participates_in CCO:P0003048 ! negative regulation of smooth muscle cell differentiation [Term] id: CCO:B0001363 name: STK6_HUMAN def: "Serine/threonine-protein kinase 6" [UniProtKB:O14965] synonym: "Aurora kinase A" EXACT [UniProtKB:O14965] synonym: "Aurora-A" EXACT [UniProtKB:O14965] synonym: "Aurora-related kinase 1" EXACT [UniProtKB:O14965] synonym: "Aurora/IPL1-related kinase 1" EXACT [UniProtKB:O14965] synonym: "Breast tumor-amplified kinase" EXACT [UniProtKB:O14965] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O14965] synonym: "hARK1" EXACT [UniProtKB:O14965] synonym: "Serine/threonine kinase 15" EXACT [UniProtKB:O14965] xref: EMBL:AAC12708.1 xref: EMBL:AAC23448.1 xref: EMBL:AAC63902.1 xref: EMBL:AAF29508.1 xref: EMBL:AAH01280.1 xref: EMBL:AAH02499.1 xref: EMBL:AAH06423.1 xref: EMBL:AAH27464.1 xref: EMBL:BAA23592.1 xref: EMBL:CAC12717.1 xref: UniProtKB:O14965 xref: UniProtKB:O60445 xref: UniProtKB:O75873 xref: UniProtKB:Q9BQD6 xref: UniProtKB:Q9UPG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005695 ! AURKA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006317 ! tacc1-chtog-8 colocalization relationship: participates_in CCO:I0006704 ! akip-stk6-1 physical interaction relationship: participates_in CCO:I0007021 ! stk6-tpx2-1 direct interaction relationship: participates_in CCO:I0007077 ! akip-stk6-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0001482 ! regulation of protein stability relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0014257 ! STK6_HUMAN-Phosphoserine369 relationship: transforms_into CCO:B0041199 ! STK6_HUMAN-Phosphothreonine287 relationship: transforms_into CCO:B0041200 ! STK6_HUMAN-Phosphothreonine288 [Term] id: CCO:B0001364 name: GAK_HUMAN def: "Cyclin G-associated kinase" [UniProtKB:O14976] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O14976] xref: EMBL:AAH00816.1 xref: EMBL:AAH08668.1 xref: EMBL:BAA22623.1 xref: UniProtKB:O14976 xref: UniProtKB:Q9BVY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004681 ! GAK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0008198 ! axin1-gak physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011920 ! GAK_HUMAN-Phosphoserine829 [Term] id: CCO:B0001365 name: TBX3_HUMAN def: "T-box transcription factor TBX3" [UniProtKB:O15119] synonym: "T-box protein 3" EXACT [UniProtKB:O15119] xref: EMBL:AAC12947.1 xref: EMBL:AAD50989.2 xref: EMBL:AAF61207.1 xref: EMBL:AAF61816.1 xref: EMBL:AAH25258.1 xref: UniProtKB:O15119 xref: UniProtKB:Q8TB20 xref: UniProtKB:Q9UKF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005747 ! TBX3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000247 ! positive regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002476 ! negative regulation of myoblast differentiation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014321 ! TBX3_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0014322 ! TBX3_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0048405 ! TBX3_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0048406 ! TBX3_HUMAN-Phosphoserine438 relationship: transforms_into CCO:B0048407 ! TBX3_HUMAN-Phosphothreonine441 [Term] id: CCO:B0001366 name: MDM4_HUMAN def: "Protein Mdm4" [UniProtKB:O15151] synonym: "Double minute 4 protein" EXACT [UniProtKB:O15151] synonym: "Mdm2-like p53-binding protein" EXACT [UniProtKB:O15151] synonym: "p53-binding protein Mdm4" EXACT [UniProtKB:O15151] synonym: "Protein Mdmx" EXACT [UniProtKB:O15151] xref: EMBL:AAB62928.1 xref: EMBL:AAH67299.1 xref: EMBL:AAO13494.1 xref: EMBL:BAD96948.1 xref: EMBL:CAI14100.1 xref: UniProtKB:O15151 xref: UniProtKB:Q6GS18 xref: UniProtKB:Q8IV83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005053 ! MDM4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006016 ! mdm2-mdm4-1 physical interaction relationship: participates_in CCO:I0007339 ! mdm2-mdm4-2 physical interaction relationship: participates_in CCO:I0007340 ! mdm2-mdm4-3 physical interaction relationship: participates_in CCO:I0007407 ! mdm2-mdm4-4 physical interaction relationship: participates_in CCO:P0000235 ! G0 to G1 transition relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0001367 name: AXN1_HUMAN def: "Axin-1" [UniProtKB:O15169] synonym: "Axis inhibition protein 1" EXACT [UniProtKB:O15169] synonym: "hAxin" EXACT [UniProtKB:O15169] xref: EMBL:AAC51624.1 xref: EMBL:AAH17447.1 xref: EMBL:AAH44648.1 xref: EMBL:AAK61224.1 xref: EMBL:CAI95589.2 xref: EMBL:CAI95590.2 xref: EMBL:CAI95600.2 xref: EMBL:CAI95601.2 xref: UniProtKB:O15169 xref: UniProtKB:Q4TT26 xref: UniProtKB:Q4TT27 xref: UniProtKB:Q86YA7 xref: UniProtKB:Q8WVW6 xref: UniProtKB:Q96S28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004133 ! AXIN1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000783 ! lateral plasma membrane relationship: located_in CCO:C0001067 ! beta-catenin destruction complex relationship: participates_in CCO:I0007886 ! axin1-anp32a-1 physical interaction relationship: participates_in CCO:I0007887 ! axin1-crmp1 physical interaction relationship: participates_in CCO:I0007997 ! axin1-crmp1-1 physical interaction relationship: participates_in CCO:I0007998 ! axin1-eef1a1 physical interaction relationship: participates_in CCO:I0008071 ! axin1-anp32a physical interaction relationship: participates_in CCO:I0008197 ! axin1-axin1 physical interaction relationship: participates_in CCO:I0008198 ! axin1-gak physical interaction relationship: participates_in CCO:I0008199 ! axin1-utp14a physical interaction relationship: participates_in CCO:I0008449 ! axin1-sh3gl1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0003241 ! Wnt receptor signaling pathway through beta-catenin [Term] id: CCO:B0001368 name: CETN3_HUMAN def: "Centrin-3" [UniProtKB:O15182] xref: EMBL:AAH05383.1 xref: EMBL:AAH93793.1 xref: EMBL:AAI12041.1 xref: EMBL:AAP35334.1 xref: EMBL:CAA73077.1 xref: UniProtKB:O15182 xref: UniProtKB:Q53YD2 xref: UniProtKB:Q9BS23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004334 ! CETN3_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000384 ! centriole relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: participates_in CCO:I0008085 ! cetn3-pde6d physical interaction relationship: participates_in CCO:I0008086 ! cetn3-rif1 physical interaction relationship: participates_in CCO:I0008087 ! cetn3-unc119 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000108 ! centrosome cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001369 name: MK13_HUMAN def: "Mitogen-activated protein kinase 13" [UniProtKB:O15264] synonym: "EC 2.7.11.24" EXACT [UniProtKB:O15264] synonym: "MAP kinase p38 delta" EXACT [UniProtKB:O15264] synonym: "Mitogen-activated protein kinase p38 delta" EXACT [UniProtKB:O15264] synonym: "Stress-activated protein kinase 4" EXACT [UniProtKB:O15264] xref: EMBL:AAB87639.1 xref: EMBL:AAC51374.1 xref: EMBL:AAC51758.1 xref: EMBL:AAD23377.1 xref: EMBL:AAF36772.1 xref: EMBL:AAH00433.1 xref: EMBL:AAH01641.1 xref: EMBL:AAH04428.1 xref: EMBL:AAP35885.1 xref: EMBL:CAA71512.1 xref: EMBL:CAB08438.1 xref: UniProtKB:O14739 xref: UniProtKB:O15124 xref: UniProtKB:O15264 xref: UniProtKB:Q9UNU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005096 ! MAPK13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0012959 ! MK13_HUMAN-Phosphothreonine180 relationship: transforms_into CCO:B0012960 ! MK13_HUMAN-Phosphotyrosine182 relationship: transforms_into CCO:B0041160 ! MK13_HUMAN-Phosphoserine47 [Term] id: CCO:B0001370 name: FANCG_HUMAN def: "Fanconi anemia group G protein" [UniProtKB:O15287] synonym: "DNA repair protein XRCC9" EXACT [UniProtKB:O15287] synonym: "Protein FACG" EXACT [UniProtKB:O15287] xref: EMBL:AAB80802.1 xref: EMBL:AAC07981.1 xref: EMBL:AAH00032.1 xref: EMBL:AAH11623.1 xref: EMBL:AAV40841.1 xref: EMBL:CAA07602.1 xref: EMBL:CAH70994.1 xref: UniProtKB:O15287 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004611 ! FANCG_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000373 ! microsome relationship: participates_in CCO:I0005768 ! fancg-gabpb2 physical interaction relationship: participates_in CCO:I0005796 ! fancg-zbed1x physical interaction relationship: participates_in CCO:I0005841 ! fancg-samd3 physical interaction relationship: participates_in CCO:I0005909 ! fancg-ushbp1 physical interaction relationship: participates_in CCO:I0005959 ! fanca-fancg physical interaction relationship: participates_in CCO:I0007402 ! fance-fanca-1 physical interaction relationship: participates_in CCO:I0007403 ! fance-fanca-2 physical interaction relationship: participates_in CCO:I0007587 ! fancg-fancf-1 physical interaction relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000673 ! caspase activation [Term] id: CCO:B0001371 name: LX15B_HUMAN def: "Arachidonate 15-lipoxygenase type II" [UniProtKB:O15296] synonym: "15-lipoxygenase 2" EXACT [UniProtKB:O15296] synonym: "15-LOX-2" EXACT [UniProtKB:O15296] synonym: "EC 1.13.11.33" EXACT [UniProtKB:O15296] xref: EMBL:AAB61706.1 xref: EMBL:AAD37786.1 xref: EMBL:AAH35217.1 xref: EMBL:AAH63647.1 xref: EMBL:AAL76274.1 xref: EMBL:AAL76275.1 xref: EMBL:AAL76276.1 xref: EMBL:AAL76277.1 xref: EMBL:CAC34521.1 xref: UniProtKB:O15296 xref: UniProtKB:Q8IYQ2 xref: UniProtKB:Q8TEV3 xref: UniProtKB:Q8TEV4 xref: UniProtKB:Q8TEV5 xref: UniProtKB:Q8TEV6 xref: UniProtKB:Q9UKM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004997 ! ALOX15B_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003056 ! lipoxygenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007816 ! arachidonate 15-lipoxygenase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001342 ! regulation of epithelial cell differentiation [Term] id: CCO:B0001372 name: PPM1D_HUMAN def: "Protein phosphatase 1D" [UniProtKB:O15297] synonym: "EC 3.1.3.16" EXACT [UniProtKB:O15297] synonym: "p53-induced protein phosphatase 1" EXACT [UniProtKB:O15297] synonym: "PP2C-delta" EXACT [UniProtKB:O15297] synonym: "Protein phosphatase 2C isoform delta" EXACT [UniProtKB:O15297] synonym: "Protein phosphatase magnesium-dependent 1 delta" EXACT [UniProtKB:O15297] xref: EMBL:AAB61637.1 xref: EMBL:AAH16480.1 xref: UniProtKB:O15297 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005367 ! PPM1D_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000541 ! protein serine/threonine phosphatase complex relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001373 name: RA51B_HUMAN def: "DNA repair protein RAD51 homolog 2" [UniProtKB:O15315] synonym: "R51H2" EXACT [UniProtKB:O15315] synonym: "RAD51-like protein 1" EXACT [UniProtKB:O15315] synonym: "Rad51B" EXACT [UniProtKB:O15315] xref: EMBL:AAB63358.1 xref: EMBL:AAC32425.1 xref: EMBL:AAC32426.1 xref: EMBL:AAC39723.1 xref: EMBL:AAH30219.1 xref: EMBL:AAN60542.1 xref: EMBL:AAN60543.1 xref: EMBL:AAN60544.1 xref: EMBL:AAZ85144.1 xref: EMBL:CAA75680.1 xref: EMBL:CAD61950.1 xref: EMBL:CAD62357.1 xref: EMBL:CAD66573.1 xref: UniProtKB:O15315 xref: UniProtKB:O60914 xref: UniProtKB:O75210 xref: UniProtKB:Q3Y4F8 xref: UniProtKB:Q86SY3 xref: UniProtKB:Q86SY4 xref: UniProtKB:Q86TR0 xref: UniProtKB:Q86U92 xref: UniProtKB:Q86U93 xref: UniProtKB:Q86U94 xref: UniProtKB:Q8N6H4 xref: UniProtKB:Q9UPL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005406 ! RAD51L1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0001374 name: P73_HUMAN def: "Tumor protein p73" [UniProtKB:O15350] synonym: "p53-like transcription factor" EXACT [UniProtKB:O15350] synonym: "p53-related protein" EXACT [UniProtKB:O15350] xref: EMBL:AAC61887.1 xref: EMBL:AAD39696.1 xref: EMBL:AAI17252.1 xref: EMBL:AAI17254.1 xref: EMBL:AAK81884.1 xref: EMBL:AAK81885.1 xref: EMBL:AAK81886.1 xref: EMBL:BAB87244.1 xref: EMBL:BAB87245.1 xref: EMBL:CAA72219.1 xref: EMBL:CAA72220.1 xref: EMBL:CAA72221.1 xref: EMBL:CAI19123.1 xref: EMBL:CAI19124.1 xref: EMBL:CAI19125.1 xref: EMBL:CAI19126.1 xref: EMBL:CAI19127.1 xref: UniProtKB:O15350 xref: UniProtKB:O15351 xref: UniProtKB:Q17RN8 xref: UniProtKB:Q5TBV5 xref: UniProtKB:Q5TBV6 xref: UniProtKB:Q8NHW9 xref: UniProtKB:Q8TDY5 xref: UniProtKB:Q8TDY6 xref: UniProtKB:Q9NTK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005248 ! TP73_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007526 ! hmgb1-tp73-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000645 ! mismatch repair relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013361 ! P73_HUMAN-Phosphotyrosine99 [Term] id: CCO:B0001375 name: PPM1G_HUMAN def: "Protein phosphatase 1G" [UniProtKB:O15355] synonym: "EC 3.1.3.16" EXACT [UniProtKB:O15355] synonym: "PP2C-gamma" EXACT [UniProtKB:O15355] synonym: "Protein phosphatase 1C" EXACT [UniProtKB:O15355] synonym: "Protein phosphatase 2C isoform gamma" EXACT [UniProtKB:O15355] synonym: "Protein phosphatase magnesium-dependent 1 gamma" EXACT [UniProtKB:O15355] xref: EMBL:AAH00057.1 xref: EMBL:AAH22061.1 xref: EMBL:CAA74245.1 xref: UniProtKB:O15355 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005368 ! PPM1G_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0008482 ! lrpap1-ppm1g physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0013605 ! PPM1G_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0013606 ! PPM1G_HUMAN-Phosphoserine527 [Term] id: CCO:B0001376 name: HDAC3_HUMAN def: "Histone deacetylase 3" [UniProtKB:O15379] synonym: "EC 3.5.1.98" EXACT [UniProtKB:O15379] synonym: "HD3" EXACT [UniProtKB:O15379] synonym: "RPD3-2" EXACT [UniProtKB:O15379] synonym: "SMAP45" EXACT [UniProtKB:O15379] xref: EMBL:AAB87752.1 xref: EMBL:AAB88240.1 xref: EMBL:AAB88241.1 xref: EMBL:AAC08351.1 xref: EMBL:AAC08352.1 xref: EMBL:AAC26509.1 xref: EMBL:AAC52038.1 xref: EMBL:AAC98927.1 xref: EMBL:AAH00614.1 xref: UniProtKB:O15379 xref: UniProtKB:O43268 xref: UniProtKB:Q9UEI5 xref: UniProtKB:Q9UEV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004788 ! HDAC3_human relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006003 ! hdac10-hdac3-1 physical interaction relationship: participates_in CCO:I0006339 ! rar-mbd1 physical interaction relationship: participates_in CCO:I0007134 ! hdac3-mbd1-1 physical interaction relationship: participates_in CCO:I0007191 ! hdac3-brms1 physical interaction relationship: participates_in CCO:I0007450 ! hdac3-mbd1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0001377 name: BIRC5_HUMAN def: "Baculoviral IAP repeat-containing protein 5" [UniProtKB:O15392] synonym: "Apoptosis inhibitor 4" EXACT [UniProtKB:O15392] synonym: "Apoptosis inhibitor survivin" EXACT [UniProtKB:O15392] xref: EMBL:AAC51660.1 xref: EMBL:AAD34226.1 xref: EMBL:AAH08718.1 xref: EMBL:AAH34148.1 xref: EMBL:AAH65497.1 xref: EMBL:AAV40840.1 xref: EMBL:AAW22624.1 xref: EMBL:AAY15202.1 xref: EMBL:ABC42341.1 xref: EMBL:ABC42342.1 xref: EMBL:ABC42343.1 xref: EMBL:ABC42344.1 xref: EMBL:ABC42345.1 xref: EMBL:BAA93676.1 xref: EMBL:BAD11155.1 xref: EMBL:BAD97148.1 xref: EMBL:CAG46540.1 xref: UniProtKB:O15392 xref: UniProtKB:Q2I3N8 xref: UniProtKB:Q4VGX0 xref: UniProtKB:Q53F61 xref: UniProtKB:Q5MGC6 xref: UniProtKB:Q6FHL2 xref: UniProtKB:Q75SP2 xref: UniProtKB:Q9P2W8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004166 ! BIRC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007348 ! birc5-casp9 physical interaction relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000177 ! positive regulation of exit from mitosis relationship: participates_in CCO:P0000190 ! spindle checkpoint relationship: participates_in CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 [Term] id: CCO:B0001378 name: MSH4_HUMAN def: "MutS protein homolog 4" [UniProtKB:O15457] xref: EMBL:AAB72039.1 xref: EMBL:AAD17920.1 xref: EMBL:AAH33030.1 xref: EMBL:AAP03427.1 xref: UniProtKB:O15457 xref: UniProtKB:Q8NEB3 xref: UniProtKB:Q9UNP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005128 ! MSH4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000122 ! synaptonemal complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000120 ! synapsis relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0001379 name: FGF10_HUMAN def: "Fibroblast growth factor 10 precursor" [UniProtKB:O15520] synonym: "FGF-10" EXACT [UniProtKB:O15520] synonym: "Keratinocyte growth factor 2" EXACT [UniProtKB:O15520] xref: EMBL:AAB61991.1 xref: EMBL:AAH69561.1 xref: EMBL:AAI05022.1 xref: EMBL:AAI05024.1 xref: EMBL:AAL05875.1 xref: EMBL:AAS99733.1 xref: EMBL:BAA22331.1 xref: EMBL:CAG46466.1 xref: UniProtKB:O15520 xref: UniProtKB:Q6FHT6 xref: UniProtKB:Q96P59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004631 ! FGF10_human relationship: has_function CCO:F0001409 ! fibroblast growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0005617 ! chemoattractant activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0007827 ! fgf10-fgfr2-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0001248 ! positive regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0001356 ! positive regulation of vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: participates_in CCO:P0002802 ! positive regulation of receptor-mediated endocytosis relationship: participates_in CCO:P0002918 ! urothelial cell proliferation relationship: participates_in CCO:P0002921 ! positive regulation of urothelial cell proliferation [Term] id: CCO:B0001380 name: ZZEF1_HUMAN def: "Zinc finger ZZ-type and EF-hand domain-containing protein 1" [UniProtKB:O43149] xref: EMBL:AAH67099.1 xref: EMBL:BAA23695.4 xref: EMBL:BAA91834.1 xref: EMBL:BAC86999.1 xref: EMBL:BAC87412.1 xref: UniProtKB:O43149 xref: UniProtKB:Q6NXG0 xref: UniProtKB:Q6ZRA1 xref: UniProtKB:Q6ZSF4 xref: UniProtKB:Q9NVB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005977 ! ZZEF1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition relationship: transforms_into CCO:B0014779 ! ZZEF1_HUMAN-Phosphoserine1464 relationship: transforms_into CCO:B0014780 ! ZZEF1_HUMAN-Phosphoserine2444 relationship: transforms_into CCO:B0048431 ! ZZEF1_HUMAN-Phosphotyrosine976 [Term] id: CCO:B0001381 name: MSH5_HUMAN def: "MutS protein homolog 5" [UniProtKB:O43196] xref: EMBL:AAB87632.1 xref: EMBL:AAC62533.1 xref: EMBL:AAC62534.1 xref: EMBL:AAC70066.1 xref: EMBL:AAC70067.1 xref: EMBL:AAD18072.1 xref: EMBL:AAD21822.1 xref: EMBL:AAH01358.1 xref: EMBL:AAH02498.1 xref: EMBL:AAH41031.1 xref: EMBL:AAP35864.1 xref: EMBL:AAX20111.1 xref: EMBL:BAB63375.1 xref: EMBL:CAI17723.1 xref: EMBL:CAI17724.1 xref: EMBL:CAI18423.1 xref: EMBL:CAI18424.1 xref: UniProtKB:O43196 xref: UniProtKB:O60586 xref: UniProtKB:Q5BLU9 xref: UniProtKB:Q5SSR1 xref: UniProtKB:Q8IW44 xref: UniProtKB:Q9BQC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000127 ! meiotic prophase II relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0001382 name: SEPT4_HUMAN def: "Septin-4" [UniProtKB:O43236] synonym: "Bradeion beta" EXACT [UniProtKB:O43236] synonym: "Brain protein H5" EXACT [UniProtKB:O43236] synonym: "CE5B3 beta" EXACT [UniProtKB:O43236] synonym: "Cell division control-related protein 2" EXACT [UniProtKB:O43236] synonym: "Cerebral protein 7" EXACT [UniProtKB:O43236] synonym: "hCDCREL-2" EXACT [UniProtKB:O43236] synonym: "Peanut-like protein 2" EXACT [UniProtKB:O43236] xref: EMBL:AAB88512.1 xref: EMBL:AAC25673.1 xref: EMBL:AAD00653.1 xref: EMBL:AAD00657.1 xref: EMBL:AAH18056.3 xref: EMBL:BAB46922.1 xref: EMBL:BAB70695.1 xref: EMBL:CAG33392.1 xref: EMBL:EAW94440.1 xref: UniProtKB:O43236 xref: UniProtKB:Q6IAP3 xref: UniProtKB:Q9UM58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005587 ! SEPT4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013995 ! SEPT4_HUMAN-Phosphoserine325 [Term] id: CCO:B0001383 name: KLK10_HUMAN def: "Kallikrein-10 precursor" [UniProtKB:O43240] synonym: "EC 3.4.21.-" EXACT [UniProtKB:O43240] synonym: "Normal epithelial cell-specific 1" EXACT [UniProtKB:O43240] synonym: "Protease serine-like 1" EXACT [UniProtKB:O43240] xref: EMBL:AAB81602.1 xref: EMBL:AAC14266.1 xref: EMBL:AAG23256.1 xref: EMBL:AAG33363.1 xref: EMBL:AAH02710.1 xref: EMBL:AAS66976.1 xref: UniProtKB:A6NC12 xref: UniProtKB:O43240 xref: UniProtKB:Q53YL3 xref: UniProtKB:Q99920 xref: UniProtKB:Q9GZW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004954 ! KLK10_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0008402 ! klk10-rif1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001384 name: SIAH2_HUMAN def: "E3 ubiquitin-protein ligase SIAH2" [UniProtKB:O43255] synonym: "EC 6.3.2.-" EXACT [UniProtKB:O43255] synonym: "hSiah2" EXACT [UniProtKB:O43255] synonym: "Seven in absentia homolog 2" EXACT [UniProtKB:O43255] synonym: "Siah-2" EXACT [UniProtKB:O43255] xref: EMBL:AAC51908.1 xref: EMBL:AAH13082.1 xref: EMBL:CAA75557.1 xref: UniProtKB:O43255 xref: UniProtKB:O43270 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005613 ! SIAH2_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007617 ! atn1-siah2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0001385 name: LEU1_HUMAN def: "Leukemia-associated protein 1" [UniProtKB:O43261] synonym: "Deleted in lymphocytic leukemia 1" EXACT [UniProtKB:O43261] xref: EMBL:AAH20692.1 xref: EMBL:AAL95698.1 xref: EMBL:CAA75515.1 xref: EMBL:CAA75600.1 xref: EMBL:CAC43393.1 xref: UniProtKB:O43261 xref: UniProtKB:Q8TE10 xref: UniProtKB:Q96QY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004977 ! DLEU1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007576 ! htatip-dleu1-1 physical interaction relationship: participates_in CCO:I0007985 ! dleu1-eef1a1 physical interaction relationship: participates_in CCO:I0007986 ! dleu1-eef1g physical interaction relationship: participates_in CCO:I0008092 ! dleu1-med31 physical interaction relationship: participates_in CCO:I0008093 ! dleu1-cops6 physical interaction relationship: participates_in CCO:I0008094 ! dleu1-htatip physical interaction relationship: participates_in CCO:I0008095 ! dleu1-kiaa1377 physical interaction relationship: participates_in CCO:I0008096 ! dleu1-utp14a physical interaction relationship: participates_in CCO:I0008097 ! dleu1-tp53 physical interaction relationship: participates_in CCO:I0008098 ! dleu1-ubr1 physical interaction relationship: participates_in CCO:I0008219 ! dleu1-psma1 physical interaction relationship: participates_in CCO:I0008220 ! dleu1-setdb1 physical interaction relationship: participates_in CCO:I0008221 ! dleu1-shmt1 physical interaction relationship: participates_in CCO:I0008222 ! dleu1-tle1 physical interaction relationship: participates_in CCO:I0008381 ! dleu1-abcd4 physical interaction relationship: participates_in CCO:I0008382 ! dleu1-gdf9 physical interaction relationship: participates_in CCO:I0008467 ! dleu1-arl10c physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001386 name: LEU2_HUMAN def: "Leukemia-associated protein 2" [UniProtKB:O43262] synonym: "Deleted in lymphocytic leukemia 2" EXACT [UniProtKB:O43262] xref: EMBL:AAH17819.1 xref: EMBL:AAH22282.1 xref: EMBL:AAH30971.1 xref: EMBL:AAH55417.1 xref: EMBL:AAH70292.1 xref: EMBL:CAA75516.1 xref: EMBL:EAX08851.1 xref: UniProtKB:O43262 xref: UniProtKB:Q7Z2U1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004978 ! DLEU2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001387 name: ZW10_HUMAN def: "Centromere/kinetochore protein zw10 homolog" [UniProtKB:O43264] xref: EMBL:AAB88237.1 xref: UniProtKB:O43264 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005973 ! ZW10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006066 ! kntc2_zwint_5 physical interaction relationship: participates_in CCO:I0006447 ! zw10_zwint_2 colocalization relationship: participates_in CCO:I0006750 ! zwint_zw10_2 colocalization relationship: participates_in CCO:I0006751 ! mad1l1_zw10_1 colocalization relationship: participates_in CCO:I0006752 ! zw10_bub1_1 colocalization relationship: participates_in CCO:I0006753 ! zw10_bub1b_2 colocalization relationship: participates_in CCO:I0006754 ! zw10_dync1l1_1 colocalization relationship: participates_in CCO:I0006756 ! zw10_zwint_1 colocalization relationship: participates_in CCO:I0006757 ! kntc2_zw10_2 colocalization relationship: participates_in CCO:I0007158 ! zwint_kntc2_2 physical interaction relationship: participates_in CCO:I0007159 ! kntc2_zwint_3 physical interaction relationship: participates_in CCO:I0007160 ! zw10_kntc2_1 physical interaction relationship: participates_in CCO:I0007819 ! zw10_zwilch_1 physical interaction relationship: participates_in CCO:I0007820 ! zwint_zw10_1 physical interaction relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: transforms_into CCO:B0041345 ! ZW10_HUMAN-N-acetylalanine2 [Term] id: CCO:B0001388 name: SNUT1_HUMAN def: "U4/U6.U5 tri-snRNP-associated protein 1" [UniProtKB:O43290] synonym: "Allergen Hom s 1" EXACT [UniProtKB:O43290] synonym: "hSART-1" EXACT [UniProtKB:O43290] synonym: "hSnu66" EXACT [UniProtKB:O43290] synonym: "SART-1" EXACT [UniProtKB:O43290] synonym: "Squamous cell carcinoma antigen recognized by T cells 1" EXACT [UniProtKB:O43290] synonym: "U4/U6.U5 tri-snRNP-associated 110 kDa protein" EXACT [UniProtKB:O43290] xref: EMBL:AAD20223.1 xref: EMBL:AAH01058.1 xref: EMBL:AAK49523.1 xref: EMBL:AAP35283.1 xref: EMBL:BAA24056.1 xref: EMBL:BAD96736.1 xref: UniProtKB:A6NDN1 xref: UniProtKB:O43290 xref: UniProtKB:Q53GB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005646 ! SART1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007564 ! ubl5-sart1-1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: participates_in CCO:P0002399 ! positive regulation of cytotoxic T cell differentiation relationship: transforms_into CCO:B0014144 ! SNUT1_HUMAN-Phosphothreonine392 relationship: transforms_into CCO:B0014145 ! SNUT1_HUMAN-Phosphothreonine430 relationship: transforms_into CCO:B0014146 ! SNUT1_HUMAN-Phosphoserine448 relationship: transforms_into CCO:B0014147 ! SNUT1_HUMAN-Phosphoserine591 relationship: transforms_into CCO:B0014148 ! SNUT1_HUMAN-Phosphoserine596 relationship: transforms_into CCO:B0014149 ! SNUT1_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0014150 ! SNUT1_HUMAN-Phosphothreonine695 [Term] id: CCO:B0001389 name: CE110_HUMAN def: "Centrosomal protein of 110 kDa" [UniProtKB:O43303] synonym: "Cep110" EXACT [UniProtKB:O43303] xref: EMBL:AAC05804.1 xref: EMBL:AAH36654.1 xref: EMBL:BAA24849.2 xref: EMBL:CAH18111.1 xref: UniProtKB:O43303 xref: UniProtKB:O43335 xref: UniProtKB:Q68DV9 xref: UniProtKB:Q8NE13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004316 ! CEP110_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000300 ! centrosome duplication relationship: transforms_into CCO:B0011130 ! CE110_HUMAN-Phosphoserine641 [Term] id: CCO:B0001390 name: MTSS1_HUMAN def: "Metastasis suppressor protein 1" [UniProtKB:O43312] synonym: "Metastasis suppressor YGL-1" EXACT [UniProtKB:O43312] synonym: "Missing in metastasis protein" EXACT [UniProtKB:O43312] xref: EMBL:AAF15947.1 xref: EMBL:AAH23998.1 xref: EMBL:BAA24859.3 xref: UniProtKB:O43312 xref: UniProtKB:Q8TCA2 xref: UniProtKB:Q96RX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005136 ! MTSS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006183 ! hd-mtss1 physical interaction relationship: participates_in CCO:I0006184 ! hd-mtss1-1 physical interaction relationship: participates_in CCO:I0006185 ! hd-mtss1-2 physical interaction relationship: participates_in CCO:I0008426 ! recql5-mtss1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0013036 ! MTSS1_HUMAN-Phosphothreonine258 relationship: transforms_into CCO:B0013037 ! MTSS1_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0013038 ! MTSS1_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0013039 ! MTSS1_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0013040 ! MTSS1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0031341 ! MTSS1_HUMAN-Phosphotyrosine526 relationship: transforms_into CCO:B0041161 ! MTSS1_HUMAN-Phosphoserine261 [Term] id: CCO:B0001391 name: SUV91_HUMAN def: "Histone-lysine N-methyltransferase SUV39H1" [UniProtKB:O43463] synonym: "EC 2.1.1.43" EXACT [UniProtKB:O43463] synonym: "H3-K9-HMTase 1" EXACT [UniProtKB:O43463] synonym: "Histone H3-K9 methyltransferase 1" EXACT [UniProtKB:O43463] synonym: "Lysine N-methyltransferase 1A" EXACT [UniProtKB:O43463] synonym: "Position-effect variegation 3-9 homolog" EXACT [UniProtKB:O43463] synonym: "Su(var)3-9 homolog 1" EXACT [UniProtKB:O43463] synonym: "Suppressor of variegation 3-9 homolog 1" EXACT [UniProtKB:O43463] xref: EMBL:AAB92224.1 xref: EMBL:AAH06238.1 xref: EMBL:BAD96791.1 xref: EMBL:CAG46546.1 xref: UniProtKB:O43463 xref: UniProtKB:Q53G60 xref: UniProtKB:Q6FHK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005706 ! SUV39H1_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0005616 ! histone methyltransferase activity relationship: has_function CCO:F0006291 ! histone lysine N-methyltransferase activity (H3-K9 specific) relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0005942 ! cbx5-suv39h1 physical interaction relationship: participates_in CCO:I0006742 ! pml-suv39h1-2 physical interaction relationship: participates_in CCO:I0006904 ! mbde-suv93h1-1 physical interaction relationship: participates_in CCO:I0006905 ! suv93h1-mbde-1 physical interaction relationship: participates_in CCO:I0006906 ! suv93h1-mbd1-4 colocalization relationship: participates_in CCO:I0007459 ! suv39h1-hdac2-3 physical interaction relationship: participates_in CCO:I0007460 ! suv39h1-hdac1-3 physical interaction relationship: participates_in CCO:I0007726 ! h3fa-suv39h1 physical interaction relationship: participates_in CCO:I0007972 ! mbde-suv93h1-2 physical interaction relationship: participates_in CCO:I0007973 ! suv93h1-mbde-2 physical interaction relationship: participates_in CCO:I0007974 ! suv93h1-cbx-1 physical interaction relationship: participates_in CCO:I0007975 ! suv93h1-hdac1-1 physical interaction relationship: participates_in CCO:I0007976 ! suv93h1-hdac1-2 physical interaction relationship: participates_in CCO:I0007977 ! suv93h1-hdac2-1 physical interaction relationship: participates_in CCO:I0007978 ! suv93h1-hdac2-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014273 ! SUV91_HUMAN-Phosphoserine391 [Term] id: CCO:B0001392 name: XRCC2_HUMAN def: "DNA repair protein XRCC2" [UniProtKB:O43543] synonym: "X-ray repair cross-complementing protein 2" EXACT [UniProtKB:O43543] xref: EMBL:AAC05369.1 xref: EMBL:AAC05802.1 xref: EMBL:AAH42137.1 xref: EMBL:AAM55241.1 xref: EMBL:CAA70065.1 xref: EMBL:CAA76597.1 xref: UniProtKB:O43543 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005945 ! XRCC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000117 ! meiosis relationship: transforms_into CCO:B0014717 ! XRCC2_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0014718 ! XRCC2_HUMAN-Phosphoserine249 [Term] id: CCO:B0001393 name: O43550_HUMAN def: "Cdc25B phosphatase" [UniProtKB:O43550] xref: EMBL:AAB94625.1 xref: UniProtKB:O43550 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005118 ! CDC25B_human relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle [Term] id: CCO:B0001394 name: PRC1_HUMAN def: "Protein regulator of cytokinesis 1" [UniProtKB:O43663] xref: EMBL:AAC02688.1 xref: EMBL:AAH03138.1 xref: EMBL:AAH05140.1 xref: EMBL:BAG59623.1 xref: UniProtKB:A6NC44 xref: UniProtKB:B4DLR1 xref: UniProtKB:O43663 xref: UniProtKB:Q9BSB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005373 ! PRC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000001 ! mitotic spindle elongation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013608 ! PRC1_HUMAN-Phosphoserine195 relationship: transforms_into CCO:B0013609 ! PRC1_HUMAN-Phosphothreonine470 relationship: transforms_into CCO:B0013610 ! PRC1_HUMAN-Phosphothreonine481 relationship: transforms_into CCO:B0013611 ! PRC1_HUMAN-Phosphoserine592 [Term] id: CCO:B0001395 name: BUB1_HUMAN def: "Mitotic checkpoint serine/threonine-protein kinase BUB1" [UniProtKB:O43683] synonym: "BUB1A" EXACT [UniProtKB:O43683] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O43683] synonym: "hBUB1" EXACT [UniProtKB:O43683] xref: EMBL:AAB97855.2 xref: EMBL:AAC03122.1 xref: EMBL:AAC06259.1 xref: EMBL:AAC12729.1 xref: EMBL:AAC39546.1 xref: EMBL:AAD43675.1 xref: EMBL:AAH28201.1 xref: UniProtKB:O43430 xref: UniProtKB:O43643 xref: UniProtKB:O43683 xref: UniProtKB:O60626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004199 ! BUB1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000386 ! spindle pole body relationship: participates_in CCO:I0005890 ! arih2-bub1 physical interaction relationship: participates_in CCO:I0006752 ! zw10_bub1_1 colocalization relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000105 ! mitotic cell cycle spindle assembly checkpoint relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010869 ! BUB1_HUMAN-Phosphoserine314 [Term] id: CCO:B0001396 name: BUB3_HUMAN def: "Mitotic checkpoint protein BUB3" [UniProtKB:O43684] xref: EMBL:AAC06258.1 xref: EMBL:AAC28438.1 xref: EMBL:AAC28439.1 xref: EMBL:AAC36307.1 xref: EMBL:AAH05138.1 xref: EMBL:AAH22438.1 xref: UniProtKB:O43684 xref: UniProtKB:O43685 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004200 ! BUB3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0010870 ! BUB3_HUMAN-Phosphoserine211 [Term] id: CCO:B0001397 name: ACTN4_HUMAN def: "Alpha-actinin-4" [UniProtKB:O43707] synonym: "F-actin cross-linking protein" EXACT [UniProtKB:O43707] synonym: "Non-muscle alpha-actinin 4" EXACT [UniProtKB:O43707] xref: EMBL:AAC17470.1 xref: EMBL:AAH05033.1 xref: EMBL:BAA24447.1 xref: UniProtKB:O43707 xref: UniProtKB:O76048 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004023 ! ACTN4_human relationship: has_function CCO:F0000246 ! nucleoside binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001055 ! cortical cytoskeleton relationship: located_in CCO:C0001136 ! pseudopodium relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0005830 ! actn4-myoz2 physical interaction relationship: participates_in CCO:I0005925 ! actn4-myoz physical interaction relationship: participates_in CCO:I0005948 ! actn4-pdlim1 physical interaction relationship: participates_in CCO:I0005975 ! zo_1-actn4 physical interaction relationship: participates_in CCO:I0006376 ! map3k3-actn4 physical interaction relationship: participates_in CCO:I0006453 ! zo_1-actn4-1 physical interaction relationship: participates_in CCO:I0006539 ! cdh1-ctnna1-1 physical interaction relationship: participates_in CCO:I0007313 ! zo_1-actn4-7 colocalization relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:I0007505 ! zo_1-actn4-6 physical interaction relationship: participates_in CCO:I0007628 ! coil-actn4 physical interaction relationship: participates_in CCO:I0007695 ! sacs-actn4 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002855 ! positive regulation of pinocytosis relationship: participates_in CCO:P0003072 ! negative regulation of cell motility relationship: participates_in CCO:P0003073 ! positive regulation of cell motility relationship: transforms_into CCO:B0010449 ! ACTN4_HUMAN-Phosphotyrosine265 [Term] id: CCO:B0001398 name: TRIA1_HUMAN def: "TP53-regulated inhibitor of apoptosis 1" [UniProtKB:O43715] synonym: "p53-inducible cell-survival factor" EXACT [UniProtKB:O43715] synonym: "p53CSV" EXACT [UniProtKB:O43715] synonym: "Protein 15E1.1" EXACT [UniProtKB:O43715] synonym: "WF-1" EXACT [UniProtKB:O43715] xref: EMBL:AAF29096.1 xref: EMBL:AAH02638.1 xref: EMBL:AAH55313.1 xref: EMBL:AAR00584.1 xref: EMBL:CAA16495.1 xref: UniProtKB:O43715 xref: UniProtKB:Q5RKS5 xref: UniProtKB:Q6LCA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005831 ! TRIAP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005787 ! caspase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000065 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator [Term] id: CCO:B0001399 name: AKAP8_HUMAN def: "A-kinase anchor protein 8" [UniProtKB:O43823] synonym: "A-kinase anchor protein 95 kDa" EXACT [UniProtKB:O43823] synonym: "AKAP 95" EXACT [UniProtKB:O43823] xref: EMBL:AAC62838.1 xref: EMBL:CAA72722.1 xref: UniProtKB:O43823 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004042 ! AKAP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010482 ! AKAP8_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0010483 ! AKAP8_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0010484 ! AKAP8_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0010485 ! AKAP8_HUMAN-Phosphoserine339 [Term] id: CCO:B0001400 name: O43832_HUMAN def: "Peptidylglycine alpha-amidating monooxygenase" [UniProtKB:O43832] synonym: "EC 1.14.17.3" EXACT [UniProtKB:O43832] xref: EMBL:AAB91432.1 xref: UniProtKB:O43832 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0000901 ! peptidylglycine monooxygenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000117 ! nuclear chromatin relationship: located_in CCO:C0000120 ! condensed chromosome relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation [Term] id: CCO:B0001401 name: GAS2_HUMAN def: "Growth arrest-specific protein 2" [UniProtKB:O43903] synonym: "GAS-2" EXACT [UniProtKB:O43903] xref: EMBL:AAC52058.1 xref: EMBL:AAH40470.1 xref: EMBL:CAG29281.1 xref: UniProtKB:O43903 xref: UniProtKB:Q6ICV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004683 ! GAS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0066382 ! GAS2_HUMAN-Phosphoserine282 [Term] id: CCO:B0001402 name: VEGFD_HUMAN def: "Vascular endothelial growth factor D precursor" [UniProtKB:O43915] synonym: "c-fos-induced growth factor" EXACT [UniProtKB:O43915] synonym: "FIGF" EXACT [UniProtKB:O43915] synonym: "VEGF-D" EXACT [UniProtKB:O43915] xref: EMBL:AAH27948.1 xref: EMBL:BAA24264.1 xref: EMBL:CAA03942.1 xref: EMBL:CAA73370.1 xref: EMBL:CAA73371.1 xref: UniProtKB:O43915 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005900 ! FIGF_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005815 ! vascular endothelial growth factor receptor 3 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:B0001403 name: RAD21_HUMAN def: "Double-strand-break repair protein rad21 homolog" [UniProtKB:O60216] synonym: "hHR21" EXACT [UniProtKB:O60216] synonym: "Nuclear matrix protein 1" EXACT [UniProtKB:O60216] synonym: "NXP-1" EXACT [UniProtKB:O60216] synonym: "SCC1 homolog" EXACT [UniProtKB:O60216] xref: EMBL:AAH50381.1 xref: EMBL:AAT70725.1 xref: EMBL:BAA07554.2 xref: EMBL:CAA66940.1 xref: UniProtKB:O60216 xref: UniProtKB:Q15001 xref: UniProtKB:Q99568 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005414 ! RAD21_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006601 ! disc1-rad21 physical interaction relationship: participates_in CCO:I0006783 ! rad21-stag2 physical interaction relationship: participates_in CCO:I0007038 ! smc2l1-smc4l1 physical interaction relationship: participates_in CCO:I0007039 ! wapl-cspg6-1 physical interaction relationship: participates_in CCO:I0007040 ! wapl-cspg6-2 physical interaction relationship: participates_in CCO:I0007177 ! cspg6-rad21 physical interaction relationship: participates_in CCO:I0007711 ! wapl-cspg6-4 physical interaction relationship: participates_in CCO:I0007712 ! wapl-cspg6-5 physical interaction relationship: participates_in CCO:I0007713 ! wapl-cspg6-6 physical interaction relationship: participates_in CCO:I0007714 ! wapl-cspg6-7 physical interaction relationship: participates_in CCO:I0007715 ! wapl-cspg6-9 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001405 name: SSA27_HUMAN def: "Sjoegren syndrome/scleroderma autoantigen 1" [UniProtKB:O60232] synonym: "Autoantigen p27" EXACT [UniProtKB:O60232] xref: EMBL:AAH14791.1 xref: EMBL:BAA25263.1 xref: UniProtKB:O60232 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005674 ! SSSCA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005734 ! ccnh-sssca1 physical interaction relationship: participates_in CCO:I0005753 ! myo15b-sssca1 physical interaction relationship: participates_in CCO:I0005767 ! mgc5356-sssca1 physical interaction relationship: participates_in CCO:I0005815 ! il16-sssca1 physical interaction relationship: participates_in CCO:I0005831 ! sssca1-sssca1 physical interaction relationship: participates_in CCO:I0005836 ! cct3-sssca1 physical interaction relationship: participates_in CCO:I0005844 ! c6orf55-sssca1 physical interaction relationship: participates_in CCO:I0005879 ! mgc3162-sssca1 physical interaction relationship: participates_in CCO:I0005895 ! cct5-sssca1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014217 ! SSA27_HUMAN-Phosphoserine94 [Term] id: CCO:B0001406 name: ADCY3_HUMAN def: "Adenylate cyclase type 3" [UniProtKB:O60266] synonym: "AC-III" EXACT [UniProtKB:O60266] synonym: "AC3" EXACT [UniProtKB:O60266] synonym: "Adenylate cyclase type III" EXACT [UniProtKB:O60266] synonym: "Adenylate cyclase, olfactive type" EXACT [UniProtKB:O60266] synonym: "Adenylyl cyclase 3" EXACT [UniProtKB:O60266] synonym: "ATP pyrophosphate-lyase 3" EXACT [UniProtKB:O60266] synonym: "EC 4.6.1.1" EXACT [UniProtKB:O60266] xref: EMBL:AAD13403.1 xref: EMBL:AAI26236.1 xref: EMBL:AAY14787.1 xref: EMBL:BAA25437.1 xref: UniProtKB:O60266 xref: UniProtKB:Q53T54 xref: UniProtKB:Q9UDB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004030 ! ADCY3_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001817 ! calcium- and calmodulin-responsive adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000134 ! female meiosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0001407 name: HBP1_HUMAN def: "HMG box-containing protein 1" [UniProtKB:O60381] synonym: "High mobility group box transcription factor 1" EXACT [UniProtKB:O60381] synonym: "HMG box transcription factor 1" EXACT [UniProtKB:O60381] xref: EMBL:AAC08317.1 xref: EMBL:AAD56225.1 xref: EMBL:AAH17069.1 xref: EMBL:AAH22329.1 xref: EMBL:BAB85059.1 xref: UniProtKB:O60381 xref: UniProtKB:Q8TBM1 xref: UniProtKB:Q8TE93 xref: UniProtKB:Q96AJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004781 ! HBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006651 ! ewsr1-hbp1 physical interaction relationship: participates_in CCO:I0006662 ! hbp1-kiaa1279 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0001408 name: EVI5_HUMAN def: "Ecotropic viral integration site 5 protein homolog" [UniProtKB:O60447] synonym: "EVI-5" EXACT [UniProtKB:O60447] synonym: "Neuroblastoma stage 4S gene protein" EXACT [UniProtKB:O60447] xref: EMBL:AAC16031.1 xref: EMBL:CAC19437.2 xref: EMBL:CAI21914.1 xref: UniProtKB:A6NKX8 xref: UniProtKB:O60447 xref: UniProtKB:Q9H1Y9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004592 ! EVI5_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011773 ! EVI5_HUMAN-Phosphoserine477 relationship: transforms_into CCO:B0011774 ! EVI5_HUMAN-Phosphoserine776 relationship: transforms_into CCO:B0011775 ! EVI5_HUMAN-Phosphoserine778 [Term] id: CCO:B0001409 name: DBC1_HUMAN def: "Deleted in bladder cancer protein 1 precursor" [UniProtKB:O60477] synonym: "Protein FAM5A" EXACT [UniProtKB:O60477] xref: EMBL:AAC39691.1 xref: EMBL:AAH21560.1 xref: EMBL:AAH65196.1 xref: EMBL:AAH71702.1 xref: EMBL:CAH72027.1 xref: EMBL:CAH72028.1 xref: EMBL:CAI16000.1 xref: EMBL:CAI16001.1 xref: UniProtKB:O60477 xref: UniProtKB:Q6IPV6 xref: UniProtKB:Q6P1A0 xref: UniProtKB:Q8WU22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004440 ! DBC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001410 name: CCNT1_HUMAN def: "Cyclin-T1" [UniProtKB:O60563] synonym: "Cyclin-T" EXACT [UniProtKB:O60563] synonym: "CycT1" EXACT [UniProtKB:O60563] xref: EMBL:AAC39638.1 xref: EMBL:AAC39664.1 xref: UniProtKB:O60563 xref: UniProtKB:O60581 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004262 ! CCNT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003544 ! snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011006 ! CCNT1_HUMAN-N6-acetyllysine492 [Term] id: CCO:B0001411 name: BUB1B_HUMAN def: "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta" [UniProtKB:O60566] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O60566] synonym: "hBUBR1" EXACT [UniProtKB:O60566] synonym: "MAD3/BUB1-related protein kinase" EXACT [UniProtKB:O60566] synonym: "Mitotic checkpoint kinase MAD3L" EXACT [UniProtKB:O60566] synonym: "SSK1" EXACT [UniProtKB:O60566] xref: EMBL:AAC06260.1 xref: EMBL:AAC12730.2 xref: EMBL:AAC19118.1 xref: EMBL:AAC23736.1 xref: EMBL:AAC33435.1 xref: EMBL:AAD11941.1 xref: EMBL:AAL10712.1 xref: UniProtKB:O60501 xref: UniProtKB:O60566 xref: UniProtKB:O60627 xref: UniProtKB:O60758 xref: UniProtKB:O75389 xref: UniProtKB:Q96KM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004198 ! BUB1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006449 ! zwint_bub1b_1 colocalization relationship: participates_in CCO:I0006753 ! zw10_bub1b_2 colocalization relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 [Term] id: CCO:B0001412 name: CCNT2_HUMAN def: "Cyclin-T2" [UniProtKB:O60583] synonym: "CycT2" EXACT [UniProtKB:O60583] xref: EMBL:AAC39665.1 xref: EMBL:AAC39666.1 xref: EMBL:AAW56073.1 xref: EMBL:AAY14998.1 xref: UniProtKB:O60582 xref: UniProtKB:O60583 xref: UniProtKB:Q53SR4 xref: UniProtKB:Q5I1Y0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004263 ! CCNT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011007 ! CCNT2_HUMAN-Phosphoserine480 [Term] id: CCO:B0001413 name: RAD1_HUMAN def: "Cell cycle checkpoint protein RAD1" [UniProtKB:O60671] synonym: "DNA repair exonuclease rad1 homolog" EXACT [UniProtKB:O60671] synonym: "EC 3.1.11.2" EXACT [UniProtKB:O60671] synonym: "hRAD1" EXACT [UniProtKB:O60671] synonym: "Rad1-like DNA damage checkpoint protein" EXACT [UniProtKB:O60671] xref: EMBL:AAC14138.1 xref: EMBL:AAC27243.1 xref: EMBL:AAC35549.1 xref: EMBL:AAC35550.1 xref: EMBL:AAC95427.1 xref: EMBL:AAC95466.1 xref: EMBL:AAC95523.1 xref: EMBL:AAC95603.1 xref: EMBL:AAC98093.1 xref: EMBL:AAH06837.1 xref: EMBL:AAH09804.1 xref: EMBL:AAH37857.1 xref: EMBL:AAP35554.1 xref: EMBL:BAD86789.1 xref: EMBL:BAD86790.1 xref: EMBL:CAA06248.1 xref: EMBL:CAA06249.1 xref: UniProtKB:O60671 xref: UniProtKB:O75572 xref: UniProtKB:O95304 xref: UniProtKB:Q5KSM0 xref: UniProtKB:Q5KSM1 xref: UniProtKB:Q9UEP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005413 ! RAD1_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0002192 ! exodeoxyribonuclease III activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008415 ! park2-rad1 physical interaction relationship: participates_in CCO:I0008493 ! rad1-map1lc3b physical interaction relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000119 ! meiotic prophase I relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0001414 name: JAK2_HUMAN def: "Tyrosine-protein kinase JAK2" [UniProtKB:O60674] synonym: "EC 2.7.10.2" EXACT [UniProtKB:O60674] synonym: "JAK-2" EXACT [UniProtKB:O60674] synonym: "Janus kinase 2" EXACT [UniProtKB:O60674] xref: EMBL:AAB82092.1 xref: EMBL:AAC23653.1 xref: EMBL:AAC23982.1 xref: EMBL:CAD13329.1 xref: UniProtKB:O14636 xref: UniProtKB:O60674 xref: UniProtKB:O75297 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004908 ! JAK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0007345 ! lepr-jak2-1 physical interaction relationship: participates_in CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000777 ! tyrosine phosphorylation of STAT protein relationship: participates_in CCO:P0000779 ! STAT protein nuclear translocation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0012433 ! JAK2_HUMAN-Phosphotyrosine1007 relationship: transforms_into CCO:B0067194 ! JAK2_HUMAN-Phosphotyrosine570 relationship: transforms_into CCO:B0067195 ! JAK2_HUMAN-Phosphotyrosine813 relationship: transforms_into CCO:B0067196 ! JAK2_HUMAN-Phosphotyrosine1008 [Term] id: CCO:B0001415 name: DKC1_HUMAN def: "H/ACA ribonucleoprotein complex subunit 4" [UniProtKB:O60832] synonym: "CBF5 homolog" EXACT [UniProtKB:O60832] synonym: "Dyskerin" EXACT [UniProtKB:O60832] synonym: "EC 5.4.99.-" EXACT [UniProtKB:O60832] synonym: "Nopp140-associated protein of 57 kDa" EXACT [UniProtKB:O60832] synonym: "Nucleolar protein family A member 4" EXACT [UniProtKB:O60832] synonym: "Nucleolar protein NAP57" EXACT [UniProtKB:O60832] synonym: "snoRNP protein DKC1" EXACT [UniProtKB:O60832] xref: EMBL:AAB94299.1 xref: EMBL:AAD11815.1 xref: EMBL:AAD20232.1 xref: EMBL:AAH09928.1 xref: EMBL:AAH10015.1 xref: EMBL:CAA11970.1 xref: EMBL:CAB51168.1 xref: UniProtKB:O43845 xref: UniProtKB:O60832 xref: UniProtKB:Q96G67 xref: UniProtKB:Q9Y505 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004476 ! DKC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008091 ! dkc1-eef1g physical interaction relationship: participates_in CCO:I0008226 ! eif3s5-dkc1 physical interaction relationship: participates_in CCO:I0008324 ! ssr1-dkc1 physical interaction relationship: participates_in CCO:I0008404 ! lypla2-dkc1 physical interaction relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011511 ! DKC1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0011512 ! DKC1_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0011513 ! DKC1_HUMAN-Phosphoserine451 relationship: transforms_into CCO:B0011514 ! DKC1_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0011515 ! DKC1_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0011516 ! DKC1_HUMAN-Phosphothreonine458 relationship: transforms_into CCO:B0011517 ! DKC1_HUMAN-Phosphoserine485 relationship: transforms_into CCO:B0011518 ! DKC1_HUMAN-Phosphoserine494 relationship: transforms_into CCO:B0011519 ! DKC1_HUMAN-Phosphoserine513 [Term] id: CCO:B0001416 name: TRI13_HUMAN def: "Tripartite motif-containing protein 13" [UniProtKB:O60858] synonym: "B-cell chronic lymphocytic leukemia tumor suppressor Leu5" EXACT [UniProtKB:O60858] synonym: "Leukemia-associated protein 5" EXACT [UniProtKB:O60858] synonym: "Putative tumor suppressor RFP2" EXACT [UniProtKB:O60858] synonym: "Ret finger protein 2" EXACT [UniProtKB:O60858] synonym: "RING finger protein 77" EXACT [UniProtKB:O60858] xref: EMBL:AAF91315.1 xref: EMBL:AAG53500.1 xref: EMBL:AAG53501.1 xref: EMBL:AAH03579.1 xref: EMBL:AAH63407.1 xref: EMBL:AAK13059.1 xref: EMBL:AAK51624.1 xref: EMBL:AAO38979.1 xref: EMBL:AAR31110.1 xref: EMBL:CAA12136.1 xref: EMBL:CAC43391.1 xref: UniProtKB:O60858 xref: UniProtKB:Q9BQ47 xref: UniProtKB:Q9C021 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005827 ! TRIM13_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0001417 name: GAS7_HUMAN def: "Growth arrest-specific protein 7" [UniProtKB:O60861] synonym: "GAS-7" EXACT [UniProtKB:O60861] xref: EMBL:AAG26332.2 xref: EMBL:AAH01152.1 xref: EMBL:AAH06454.2 xref: EMBL:BAA23690.2 xref: EMBL:CAA12177.1 xref: UniProtKB:O43144 xref: UniProtKB:O60861 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004684 ! GAS7_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001418 name: DNJA2_HUMAN def: "DnaJ homolog subfamily A member 2" [UniProtKB:O60884] synonym: "Cell cycle progression restoration gene 3 protein" EXACT [UniProtKB:O60884] synonym: "Dj3" EXACT [UniProtKB:O60884] synonym: "Dnj3" EXACT [UniProtKB:O60884] synonym: "HIRA-interacting protein 4" EXACT [UniProtKB:O60884] synonym: "Renal carcinoma antigen NY-REN-14" EXACT [UniProtKB:O60884] xref: EMBL:AAB69313.1 xref: EMBL:AAH13044.1 xref: EMBL:AAH15809.1 xref: EMBL:CAA04669.1 xref: EMBL:CAA73791.1 xref: UniProtKB:O14711 xref: UniProtKB:O60884 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004488 ! DNAJA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0011550 ! DNJA2_HUMAN-Phosphoserine78 [Term] id: CCO:B0001419 name: HUS1_HUMAN def: "Checkpoint protein HUS1" [UniProtKB:O60921] synonym: "hHUS1" EXACT [UniProtKB:O60921] xref: EMBL:AAC95526.1 xref: EMBL:AAD25350.1 xref: EMBL:AAH07013.1 xref: EMBL:AAM18968.1 xref: EMBL:AAV38288.1 xref: EMBL:AAV38289.1 xref: EMBL:CAA76518.1 xref: EMBL:CAG38789.1 xref: UniProtKB:O60921 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004843 ! HUS1_human relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000188 ! G1/S transition checkpoint relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication [Term] id: CCO:B0001420 name: PFD1_HUMAN def: "Prefoldin subunit 1" [UniProtKB:O60925] xref: EMBL:AAH03620.1 xref: EMBL:AAH06202.1 xref: EMBL:AAH11869.1 xref: EMBL:BAD97114.1 xref: EMBL:CAA76759.1 xref: UniProtKB:O60925 xref: UniProtKB:Q53F95 xref: UniProtKB:Q96EX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005301 ! PFDN1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0006372 ! map3k3-pfdn1 physical interaction relationship: participates_in CCO:I0008142 ! pfdn1-med31 physical interaction relationship: participates_in CCO:I0008143 ! pfdn1-git1 physical interaction relationship: participates_in CCO:I0008144 ! pfdn1-hap1 physical interaction relationship: participates_in CCO:I0008145 ! pfdn1-kiaa1377 physical interaction relationship: participates_in CCO:I0008146 ! pfdn1-rif1 physical interaction relationship: participates_in CCO:I0008147 ! pfdn1-rplp1 physical interaction relationship: participates_in CCO:I0008286 ! pfdn1-hip1 physical interaction relationship: participates_in CCO:I0008287 ! pfdn1-immt physical interaction relationship: participates_in CCO:I0008288 ! pfdn1-psme1 physical interaction relationship: participates_in CCO:I0008487 ! pfdn1-c20orf39 physical interaction relationship: participates_in CCO:I0008488 ! pfdn1-defa1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001421 name: NBN_HUMAN def: "Nibrin" [UniProtKB:O60934] synonym: "Cell cycle regulatory protein p95" EXACT [UniProtKB:O60934] synonym: "Nijmegen breakage syndrome protein 1" EXACT [UniProtKB:O60934] xref: EMBL:AAC39732.1 xref: EMBL:AAC39752.1 xref: EMBL:AAC62232.1 xref: EMBL:AAI08651.1 xref: EMBL:AAS59158.1 xref: EMBL:BAA28616.1 xref: EMBL:BAD96976.1 xref: EMBL:CAH56160.1 xref: UniProtKB:O60672 xref: UniProtKB:O60934 xref: UniProtKB:Q32NF7 xref: UniProtKB:Q53FM6 xref: UniProtKB:Q63HR6 xref: UniProtKB:Q7LDM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005159 ! NBN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006022 ! nbs1-h2afx-2 physical interaction relationship: participates_in CCO:I0006201 ! ccne1-nbs1-1 physical interaction relationship: participates_in CCO:I0006514 ! h2afx-nbs1-1 physical interaction relationship: participates_in CCO:I0006515 ! nbs1-h2afx-1 physical interaction relationship: participates_in CCO:I0006516 ! nbs1-mre11a-1 physical interaction relationship: participates_in CCO:I0006518 ! h2afx-nbs1-2 physical interaction relationship: participates_in CCO:I0006960 ! mdc1-atm-1 physical interaction relationship: participates_in CCO:I0006961 ! nbs1-mdc1-1 physical interaction relationship: participates_in CCO:I0007342 ! h2afx-nbs1-4 physical interaction relationship: participates_in CCO:I0007538 ! h2afx-nbs1-5 physical interaction relationship: participates_in CCO:I0007851 ! h2afx-nbs1-3 physical interaction relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000106 ! mitotic cell cycle G2/M transition DNA damage checkpoint relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000188 ! G1/S transition checkpoint relationship: participates_in CCO:P0001247 ! regulation of DNA replication initiation relationship: participates_in CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator relationship: transforms_into CCO:B0013103 ! NBN_HUMAN-Phosphoserine278 relationship: transforms_into CCO:B0013104 ! NBN_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0013105 ! NBN_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0013107 ! NBN_HUMAN-Phosphoserine615 [Term] id: CCO:B0001422 name: CLAP2_HUMAN def: "CLIP-associating protein 2" [UniProtKB:O75122] synonym: "Cytoplasmic linker-associated protein 2" EXACT [UniProtKB:O75122] synonym: "hOrbit2" EXACT [UniProtKB:O75122] xref: EMBL:AAH29035.1 xref: EMBL:BAA31602.1 xref: EMBL:BAB14995.1 xref: EMBL:CAB70852.1 xref: EMBL:CAC35157.1 xref: EMBL:CAC35158.1 xref: UniProtKB:O75122 xref: UniProtKB:Q7L8F6 xref: UniProtKB:Q8N6R6 xref: UniProtKB:Q9BQT3 xref: UniProtKB:Q9BQT4 xref: UniProtKB:Q9H7A3 xref: UniProtKB:Q9NSZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004367 ! CLASP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0001380 ! regulation of microtubule polymerization or depolymerization relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0011253 ! CLAP2_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0011254 ! CLAP2_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0011255 ! CLAP2_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0011256 ! CLAP2_HUMAN-Phosphoserine525 relationship: transforms_into CCO:B0011257 ! CLAP2_HUMAN-Phosphoserine529 relationship: transforms_into CCO:B0011258 ! CLAP2_HUMAN-Phosphoserine596 relationship: transforms_into CCO:B0011259 ! CLAP2_HUMAN-Phosphoserine994 relationship: transforms_into CCO:B0035993 ! CLAP2_HUMAN-Phosphoserine523 [Term] id: CCO:B0001424 name: GA45B_HUMAN def: "Growth arrest and DNA-damage-inducible protein GADD45 beta" [UniProtKB:O75293] synonym: "Myeloid differentiation primary response protein MyD118" EXACT [UniProtKB:O75293] synonym: "Negative growth regulatory protein MyD118" EXACT [UniProtKB:O75293] xref: EMBL:AAC34572.1 xref: EMBL:AAC36361.1 xref: EMBL:AAC83328.1 xref: EMBL:AAG48366.1 xref: EMBL:AAI13467.1 xref: EMBL:AAI17470.1 xref: EMBL:AAM92794.1 xref: UniProtKB:O75293 xref: UniProtKB:O75960 xref: UniProtKB:Q17R46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004675 ! GADD45B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007531 ! map3k4-gadd45-2 physical interaction relationship: participates_in CCO:P0000409 ! activation of MAPKKK activity relationship: participates_in CCO:P0000410 ! activation of MAPKK activity [Term] id: CCO:B0001425 name: TACC1_HUMAN def: "Transforming acidic coiled-coil-containing protein 1" [UniProtKB:O75410] synonym: "Gastric cancer antigen Ga55" EXACT [UniProtKB:O75410] synonym: "Taxin 1" EXACT [UniProtKB:O75410] xref: EMBL:AAC32327.1 xref: EMBL:AAH41391.1 xref: EMBL:AAK68658.1 xref: EMBL:AAL62461.1 xref: EMBL:AAL62462.1 xref: EMBL:AAL62463.2 xref: EMBL:AAN28955.1 xref: EMBL:AAO53446.1 xref: EMBL:BAA83055.1 xref: UniProtKB:O75410 xref: UniProtKB:Q6Y687 xref: UniProtKB:Q86YG7 xref: UniProtKB:Q8IUJ2 xref: UniProtKB:Q8IUJ3 xref: UniProtKB:Q8IUJ4 xref: UniProtKB:Q8IZG2 xref: UniProtKB:Q8NEY7 xref: UniProtKB:Q9UPP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005721 ! TACC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006314 ! tacc1-lsm7-2 physical interaction relationship: participates_in CCO:I0006315 ! tacc1-snrpg-2 physical interaction relationship: participates_in CCO:I0006316 ! tacc1-tdrd7-6 physical interaction relationship: participates_in CCO:I0006317 ! tacc1-chtog-8 colocalization relationship: participates_in CCO:I0006969 ! tacc1-tdrd7-8 physical interaction relationship: participates_in CCO:I0007025 ! tacc1-yeats4-1 physical interaction relationship: participates_in CCO:I0007026 ! tacc1-yeats4-2 physical interaction relationship: participates_in CCO:I0007172 ! tacc1-yeats4-4 colocalization relationship: participates_in CCO:I0007314 ! tacc1-ckap5 physical interaction relationship: participates_in CCO:I0007315 ! tacc1-yeats4 physical interaction relationship: participates_in CCO:I0007353 ! tacc1-aurkb-5 physical interaction relationship: participates_in CCO:I0007354 ! tacc1-tdrd7-1 physical interaction relationship: participates_in CCO:I0007423 ! tacc1-aurkb-4 physical interaction relationship: participates_in CCO:I0007507 ! yeats4-tacc1 physical interaction relationship: participates_in CCO:I0007508 ! tacc1-yeats4-3 colocalization relationship: participates_in CCO:I0007566 ! tacc1-chtog-6 direct interaction relationship: participates_in CCO:I0007567 ! tacc1-tdrd7-7 physical interaction relationship: participates_in CCO:I0007871 ! tacc1-chtog-7 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014293 ! TACC1_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0014294 ! TACC1_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0014295 ! TACC1_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0014296 ! TACC1_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0014297 ! TACC1_HUMAN-Phosphoserine55 relationship: transforms_into CCO:B0014298 ! TACC1_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0014299 ! TACC1_HUMAN-Phosphotyrosine533 [Term] id: CCO:B0001426 name: CC45L_HUMAN def: "CDC45-related protein" [UniProtKB:O75419] synonym: "Cdc45" EXACT [UniProtKB:O75419] synonym: "PORC-PI-1" EXACT [UniProtKB:O75419] xref: EMBL:AAC27289.1 xref: EMBL:AAC67521.1 xref: EMBL:AAD08998.1 xref: EMBL:AAH06232.1 xref: EMBL:AAH10022.1 xref: EMBL:AAP35438.1 xref: EMBL:AAQ89330.1 xref: EMBL:AAS66985.1 xref: EMBL:CAA11530.1 xref: UniProtKB:O60856 xref: UniProtKB:O75419 xref: UniProtKB:Q6UW54 xref: UniProtKB:Q9UP68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004235 ! CDC45L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006088 ! orc5l-cdc45l direct interaction relationship: participates_in CCO:I0006135 ! cdkn1a-cdc45l direct interaction relationship: participates_in CCO:I0006139 ! cdkn2a-cdc45l direct interaction relationship: participates_in CCO:P0000007 ! DNA replication checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation [Term] id: CCO:B0001427 name: KTNA1_HUMAN def: "Katanin p60 ATPase-containing subunit A1" [UniProtKB:O75449] synonym: "EC 3.6.4.3" EXACT [UniProtKB:O75449] synonym: "Katanin p60 subunit A1" EXACT [UniProtKB:O75449] synonym: "p60 katanin" EXACT [UniProtKB:O75449] xref: EMBL:AAC25114.1 xref: EMBL:AAH50428.1 xref: EMBL:CAI16431.1 xref: EMBL:CAI16432.1 xref: EMBL:CAI19504.1 xref: EMBL:CAI19505.1 xref: UniProtKB:O75449 xref: UniProtKB:Q5TFA8 xref: UniProtKB:Q5TFA9 xref: UniProtKB:Q86VN2 xref: UniProtKB:Q9NU52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004963 ! KATNA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001999 ! microtubule-severing ATPase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000324 ! interphase of mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001428 name: ERN1_HUMAN def: "Serine/threonine-protein kinase/endoribonuclease IRE1 precursor" [UniProtKB:O75460] synonym: "Endoplasmic reticulum-to-nucleus signaling 1" EXACT [UniProtKB:O75460] synonym: "hIRE1p" EXACT [UniProtKB:O75460] synonym: "Inositol-requiring protein 1" EXACT [UniProtKB:O75460] synonym: "Ire1-alpha" EXACT [UniProtKB:O75460] synonym: "IRE1a" EXACT [UniProtKB:O75460] xref: EMBL:AAC25991.1 xref: EMBL:AAI30406.1 xref: EMBL:AAI30408.1 xref: EMBL:BAD93106.1 xref: EMBL:BAF85092.1 xref: EMBL:EAW94214.1 xref: UniProtKB:A1L457 xref: UniProtKB:A8K8N8 xref: UniProtKB:A8MXS7 xref: UniProtKB:O75460 xref: UniProtKB:Q59EE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004585 ! ERN1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000918 ! endoribonuclease activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000687 ! activation of signaling protein activity involved in unfolded protein response [Term] id: CCO:B0001429 name: E2F6_HUMAN def: "Transcription factor E2F6" [UniProtKB:O75461] synonym: "E2F-6" EXACT [UniProtKB:O75461] xref: EMBL:AAC14694.1 xref: EMBL:AAC31426.1 xref: EMBL:AAH08348.1 xref: EMBL:AAI07741.1 xref: EMBL:AAM10783.1 xref: EMBL:AAM10784.1 xref: EMBL:AAM10785.1 xref: EMBL:AAY14826.1 xref: EMBL:CAD37950.1 xref: UniProtKB:O60544 xref: UniProtKB:O75461 xref: UniProtKB:Q53QY9 xref: UniProtKB:Q7Z2H6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004538 ! E2F6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0005860 ! e2f6-tfdp1 physical interaction relationship: participates_in CCO:I0005947 ! e2f6-tfdp2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011621 ! E2F6_HUMAN-Phosphoserine67 [Term] id: CCO:B0001431 name: SUPT3_HUMAN def: "Transcription initiation protein SPT3 homolog" [UniProtKB:O75486] synonym: "SPT3-like protein" EXACT [UniProtKB:O75486] xref: EMBL:AAC36098.1 xref: EMBL:AAC39904.1 xref: EMBL:AAC70014.1 xref: EMBL:AAH50384.1 xref: EMBL:BAG36602.1 xref: EMBL:CAH70846.1 xref: EMBL:CAH70848.1 xref: EMBL:CAH73344.1 xref: EMBL:CAI14625.1 xref: EMBL:CAI14627.1 xref: EMBL:CAI15664.1 xref: EMBL:CAI15666.1 xref: EMBL:CAI19927.1 xref: EMBL:EAX04274.1 xref: EMBL:EAX04275.1 xref: UniProtKB:A6NKG9 xref: UniProtKB:B2R9Q5 xref: UniProtKB:O75486 xref: UniProtKB:O76066 xref: UniProtKB:Q5TAV9 xref: UniProtKB:Q86VN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005705 ! SUPT3H_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0001432 name: GEMI_HUMAN def: "Geminin" [UniProtKB:O75496] xref: EMBL:AAC39787.1 xref: EMBL:AAH05185.1 xref: EMBL:AAH05389.1 xref: EMBL:CAC21511.1 xref: UniProtKB:O75496 xref: UniProtKB:Q9H1Z1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004693 ! GMNN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006115 ! cdkn2a-gmnn direct interaction relationship: participates_in CCO:I0006121 ! mcm6-gmnn direct interaction relationship: participates_in CCO:I0006160 ! cdkn1a-gmnn direct interaction relationship: participates_in CCO:I0006854 ! cdt1-gmnn-5 physical interaction relationship: participates_in CCO:I0007405 ! cdt1-gmnn-2 physical interaction relationship: participates_in CCO:I0007406 ! cdt1-gmnn-3 physical interaction relationship: participates_in CCO:I0007957 ! cdt1-gmnn-4 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: transforms_into CCO:B0011928 ! GEMI_HUMAN-Phosphoserine64 [Term] id: CCO:B0001433 name: TAD3L_HUMAN def: "Transcriptional adapter 3-like" [UniProtKB:O75528] synonym: "ADA3 homolog" EXACT [UniProtKB:O75528] synonym: "ADA3-like protein" EXACT [UniProtKB:O75528] synonym: "hADA3" EXACT [UniProtKB:O75528] synonym: "STAF54" EXACT [UniProtKB:O75528] xref: EMBL:AAC39903.1 xref: EMBL:AAH09240.1 xref: EMBL:AAH13433.1 xref: EMBL:CAB55957.1 xref: UniProtKB:O75528 xref: UniProtKB:Q9UFS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005723 ! TADA3L_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005747 ! loc112869-tada3l physical interaction relationship: participates_in CCO:I0005933 ! tada3l-usp5 physical interaction relationship: participates_in CCO:I0005943 ! tada2l-tada3l physical interaction relationship: participates_in CCO:I0006181 ! tada3l-pias4-1 physical interaction relationship: participates_in CCO:I0006182 ! tada3l-mageh1 physical interaction relationship: participates_in CCO:I0006190 ! tada3l-g22p1 physical interaction relationship: participates_in CCO:I0007081 ! tada3l-pias4 physical interaction relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:I0007892 ! tada3l-usp5-1 physical interaction relationship: participates_in CCO:I0008057 ! tada3l-sap18 physical interaction relationship: participates_in CCO:I0008334 ! tada3l-hspa8 physical interaction relationship: participates_in CCO:I0008335 ! tada3l-rfx1 physical interaction relationship: participates_in CCO:I0008352 ! znf7-tada3l physical interaction relationship: participates_in CCO:I0008435 ! tada3l-eif3s1 physical interaction relationship: participates_in CCO:I0008511 ! tada3l-adpgk physical interaction relationship: participates_in CCO:I0008512 ! tada3l-c10orf45 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0001434 name: RA51D_HUMAN def: "DNA repair protein RAD51 homolog 4" [UniProtKB:O75771] synonym: "R51H3" EXACT [UniProtKB:O75771] synonym: "RAD51-like protein 3" EXACT [UniProtKB:O75771] synonym: "TRAD" EXACT [UniProtKB:O75771] xref: EMBL:AAC39719.1 xref: EMBL:AAH14422.1 xref: EMBL:AAT38112.1 xref: EMBL:BAA25914.1 xref: EMBL:BAA31747.1 xref: EMBL:BAA31748.1 xref: EMBL:BAA31749.1 xref: EMBL:BAA33779.1 xref: EMBL:BAA33780.1 xref: EMBL:BAA33781.1 xref: EMBL:BAA33782.1 xref: EMBL:BAA34690.1 xref: EMBL:CAA75681.1 xref: EMBL:CAB55937.1 xref: UniProtKB:O43537 xref: UniProtKB:O60355 xref: UniProtKB:O75196 xref: UniProtKB:O75771 xref: UniProtKB:O75847 xref: UniProtKB:O75848 xref: UniProtKB:O76073 xref: UniProtKB:O76085 xref: UniProtKB:O94908 xref: UniProtKB:Q9UFU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005407 ! RAD51L3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0001435 name: CD123_HUMAN def: "Cell division cycle protein 123 homolog" [UniProtKB:O75794] synonym: "HT-1080" EXACT [UniProtKB:O75794] synonym: "Protein D123" EXACT [UniProtKB:O75794] synonym: "PZ32" EXACT [UniProtKB:O75794] xref: EMBL:AAC34738.1 xref: EMBL:AAH01600.1 xref: EMBL:AAH09598.1 xref: EMBL:BAA03593.1 xref: EMBL:CAG33247.1 xref: EMBL:CAI12495.1 xref: EMBL:CAI12496.1 xref: EMBL:CAI12497.1 xref: EMBL:CAI12498.1 xref: EMBL:CAI12499.1 xref: EMBL:CAI12500.1 xref: UniProtKB:O75794 xref: UniProtKB:Q14107 xref: UniProtKB:Q5T0L4 xref: UniProtKB:Q5T0L5 xref: UniProtKB:Q5T0L7 xref: UniProtKB:Q5T0L8 xref: UniProtKB:Q5T0L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004268 ! CDC123_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000138 ! regulation of mitotic cell cycle relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001436 name: PR15A_HUMAN def: "Protein phosphatase 1 regulatory subunit 15A" [UniProtKB:O75807] synonym: "Growth arrest and DNA damage-inducible protein GADD34" EXACT [UniProtKB:O75807] synonym: "Myeloid differentiation primary response protein MyD116 homolog" EXACT [UniProtKB:O75807] xref: EMBL:AAC25631.1 xref: EMBL:AAH03067.1 xref: EMBL:BAA91649.1 xref: EMBL:CAG33540.1 xref: EMBL:EAW52409.1 xref: UniProtKB:O75807 xref: UniProtKB:Q6IA96 xref: UniProtKB:Q9NVU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005984 ! PPP1R15A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008200 ! bcar1-ppp1r15a physical interaction relationship: participates_in CCO:I0008490 ! pou3f3-ppp1r15a physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0036022 ! PR15A_HUMAN-Phosphotyrosine262 relationship: transforms_into CCO:B0036023 ! PR15A_HUMAN-Phosphoserine264 [Term] id: CCO:B0001437 name: BCAR3_HUMAN def: "Breast cancer anti-estrogen resistance protein 3" [UniProtKB:O75815] synonym: "Novel SH2-containing protein 2" EXACT [UniProtKB:O75815] synonym: "SH2 domain-containing protein 3B" EXACT [UniProtKB:O75815] xref: EMBL:AAC39777.1 xref: EMBL:AAD28245.1 xref: EMBL:AAH39895.1 xref: EMBL:AAQ89355.1 xref: EMBL:CAH73975.1 xref: EMBL:CAI18950.1 xref: UniProtKB:O75815 xref: UniProtKB:Q6UW40 xref: UniProtKB:Q9BR50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004147 ! BCAR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0010764 ! BCAR3_HUMAN-Phosphothreonine130 relationship: transforms_into CCO:B0010765 ! BCAR3_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0010766 ! BCAR3_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0010767 ! BCAR3_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0010768 ! BCAR3_HUMAN-Phosphoserine375 [Term] id: CCO:B0001438 name: TUSC2_HUMAN def: "Tumor suppressor candidate 2" [UniProtKB:O75896] synonym: "Fus-1 protein" EXACT [UniProtKB:O75896] synonym: "Fusion 1 protein" EXACT [UniProtKB:O75896] synonym: "PDGFA-associated protein 2" EXACT [UniProtKB:O75896] xref: EMBL:AAC35497.1 xref: EMBL:AAH23976.1 xref: UniProtKB:O75896 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005844 ! TUSC2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0014556 ! TUSC2_HUMAN-Phosphoserine50 [Term] id: CCO:B0001439 name: CCNK_HUMAN def: "Cyclin-K" [UniProtKB:O75909] xref: EMBL:AAD09978.1 xref: EMBL:AAF82290.1 xref: EMBL:AAH15935.1 xref: EMBL:AAN06829.1 xref: EMBL:AAP35596.1 xref: UniProtKB:O75909 xref: UniProtKB:Q96B63 xref: UniProtKB:Q9NNY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004260 ! CCNK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005728 ! ccnk-tsc22d4 physical interaction relationship: participates_in CCO:I0005770 ! ccnk-ushbp1 physical interaction relationship: participates_in CCO:I0005775 ! ccnk-efemp2 physical interaction relationship: participates_in CCO:I0005777 ! ccnk-kcnrg physical interaction relationship: participates_in CCO:I0005781 ! ccnk-fkbp6 physical interaction relationship: participates_in CCO:I0005782 ! ccnk-stx11 physical interaction relationship: participates_in CCO:I0005784 ! ccnk-rfxdc1 physical interaction relationship: participates_in CCO:I0005798 ! ccnk-rbpms physical interaction relationship: participates_in CCO:I0005820 ! ccnk-cep76 physical interaction relationship: participates_in CCO:I0005884 ! ccnk-pepp2 physical interaction relationship: participates_in CCO:I0005900 ! ccnk-krtap4_12 physical interaction relationship: participates_in CCO:I0005904 ! ccnk-pctk3 physical interaction relationship: participates_in CCO:I0005910 ! ccnk-hmg20a physical interaction relationship: participates_in CCO:I0006215 ! atxn1-ccnk physical interaction relationship: participates_in CCO:I0006645 ! ccnk-atxn1 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011001 ! CCNK_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0011002 ! CCNK_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0011003 ! CCNK_HUMAN-Phosphoserine340 [Term] id: CCO:B0001440 name: DCTN3_HUMAN def: "Dynactin subunit 3" [UniProtKB:O75935] synonym: "Dynactin complex subunit 22 kDa subunit" EXACT [UniProtKB:O75935] synonym: "p22" EXACT [UniProtKB:O75935] xref: EMBL:AAC61280.1 xref: EMBL:AAH00319.1 xref: EMBL:AAH03004.1 xref: EMBL:AAI07698.1 xref: EMBL:CAG46687.1 xref: EMBL:CAI13143.1 xref: EMBL:CAI13144.1 xref: EMBL:CAI13145.1 xref: EMBL:CAI14178.1 xref: EMBL:CAI14180.1 xref: EMBL:CAI14181.1 xref: EMBL:CAI14182.1 xref: EMBL:EAW58440.1 xref: UniProtKB:A6NII7 xref: UniProtKB:O75935 xref: UniProtKB:Q5T1I5 xref: UniProtKB:Q5T1I7 xref: UniProtKB:Q5T8G3 xref: UniProtKB:Q9BPU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004449 ! DCTN3_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000429 ! dynactin complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0007333 ! pbx2-p22 physical interaction relationship: participates_in CCO:I0007624 ! atxn1-dctn3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001441 name: RAD17_HUMAN def: "Cell cycle checkpoint protein RAD17" [UniProtKB:O75943] synonym: "hRad17" EXACT [UniProtKB:O75943] synonym: "RF-C/activator 1 homolog" EXACT [UniProtKB:O75943] xref: EMBL:AAC36334.1 xref: EMBL:AAC95520.1 xref: EMBL:AAC97950.1 xref: EMBL:AAC97951.1 xref: EMBL:AAD01620.1 xref: EMBL:AAD17334.1 xref: EMBL:AAD38878.1 xref: EMBL:AAH32304.1 xref: EMBL:AAT09763.1 xref: EMBL:CAA04894.1 xref: EMBL:CAA06251.1 xref: EMBL:CAB46364.1 xref: EMBL:CAB59244.1 xref: EMBL:CAD97683.1 xref: UniProtKB:O75714 xref: UniProtKB:O75943 xref: UniProtKB:Q7Z3S4 xref: UniProtKB:Q9UNK7 xref: UniProtKB:Q9UNR7 xref: UniProtKB:Q9UNR8 xref: UniProtKB:Q9UPF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005412 ! RAD17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000007 ! DNA replication checkpoint relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: transforms_into CCO:B0013661 ! RAD17_HUMAN-Phosphothreonine55 relationship: transforms_into CCO:B0013662 ! RAD17_HUMAN-Phosphothreonine304 relationship: transforms_into CCO:B0013663 ! RAD17_HUMAN-Phosphoserine646 relationship: transforms_into CCO:B0013664 ! RAD17_HUMAN-Phosphoserine656 [Term] id: CCO:B0001442 name: RECQ4_HUMAN def: "ATP-dependent DNA helicase Q4" [UniProtKB:O94761] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O94761] synonym: "RecQ protein-like 4" EXACT [UniProtKB:O94761] synonym: "RecQ4" EXACT [UniProtKB:O94761] synonym: "RTS" EXACT [UniProtKB:O94761] xref: EMBL:AAH11602.2 xref: EMBL:AAH13277.2 xref: EMBL:AAZ85145.1 xref: EMBL:BAA74453.1 xref: EMBL:BAA86899.1 xref: UniProtKB:O94761 xref: UniProtKB:Q3Y424 xref: UniProtKB:Q96DW2 xref: UniProtKB:Q96F55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005461 ! RECQL4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000254 ! negative regulation of sister chromatid cohesion relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001443 name: BPAEA_HUMAN def: "Bullous pemphigoid antigen 1, isoforms 6/9/10" [UniProtKB:O94833] synonym: "BPA" EXACT [UniProtKB:O94833] synonym: "Bullous pemphigoid antigen" EXACT [UniProtKB:O94833] synonym: "Dystonia musculorum protein" EXACT [UniProtKB:O94833] synonym: "Dystonin" EXACT [UniProtKB:O94833] synonym: "Hemidesmosomal plaque protein" EXACT [UniProtKB:O94833] synonym: "Trabeculin-beta" EXACT [UniProtKB:O94833] xref: EMBL:AAH16991.1 xref: EMBL:AAL62061.1 xref: EMBL:BAA34448.2 xref: EMBL:BAB70870.1 xref: EMBL:BAC04449.1 xref: EMBL:BAC04848.1 xref: EMBL:CAI16610.1 xref: EMBL:CAI20332.1 xref: EMBL:CAI22045.1 xref: UniProtKB:O94833 xref: UniProtKB:Q5TBT0 xref: UniProtKB:Q8N1T8 xref: UniProtKB:Q8N8J3 xref: UniProtKB:Q8WXK9 xref: UniProtKB:Q96AK9 xref: UniProtKB:Q96DQ5 xref: UniProtKB:Q9H555 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004183 ! DST_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0006473 ! celsr3-bpag1 physical interaction relationship: participates_in CCO:I0006476 ! kiaa1549-bpag1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0010826 ! BPAEA_HUMAN-Phosphoserine1558 relationship: transforms_into CCO:B0010827 ! BPAEA_HUMAN-Phosphoserine5111 relationship: transforms_into CCO:B0010828 ! BPAEA_HUMAN-Phosphoserine5114 relationship: transforms_into CCO:B0010829 ! BPAEA_HUMAN-Phosphoserine5163 relationship: transforms_into CCO:B0035986 ! BPAEA_HUMAN-Phosphothreonine4352 [Term] id: CCO:B0001444 name: SASH1_HUMAN def: "SAM and SH3 domain-containing protein 1" [UniProtKB:O94885] synonym: "Proline-glutamate repeat-containing protein" EXACT [UniProtKB:O94885] xref: EMBL:AAH28303.1 xref: EMBL:AAQ55463.1 xref: EMBL:BAA34510.1 xref: EMBL:BAB14909.1 xref: EMBL:CAD47811.1 xref: EMBL:CAD92036.1 xref: UniProtKB:O94885 xref: UniProtKB:Q8TAI0 xref: UniProtKB:Q9H7R7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005565 ! SASH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0013961 ! SASH1_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0013962 ! SASH1_HUMAN-Phosphoserine731 relationship: transforms_into CCO:B0013963 ! SASH1_HUMAN-Phosphoserine821 relationship: transforms_into CCO:B0013964 ! SASH1_HUMAN-Phosphoserine839 [Term] id: CCO:B0001445 name: HEXI1_HUMAN def: "Protein HEXIM1" [UniProtKB:O94992] synonym: "Cardiac lineage protein 1" EXACT [UniProtKB:O94992] synonym: "Estrogen down-regulated gene 1 protein" EXACT [UniProtKB:O94992] synonym: "Hexamethylene bis-acetamide-inducible protein 1" EXACT [UniProtKB:O94992] synonym: "Menage a quatre protein 1" EXACT [UniProtKB:O94992] xref: EMBL:AAH06460.1 xref: EMBL:BAA36166.1 xref: UniProtKB:O94992 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004801 ! HEXIM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012180 ! HEXI1_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0012181 ! HEXI1_HUMAN-Phosphoserine98 [Term] id: CCO:B0001446 name: CCNB2_HUMAN def: "G2/mitotic-specific cyclin-B2" [UniProtKB:O95067] xref: EMBL:AAD09309.1 xref: EMBL:AAI05087.1 xref: EMBL:AAI05113.1 xref: EMBL:AAW34361.1 xref: EMBL:BAA78387.1 xref: EMBL:CAB45739.1 xref: EMBL:CAG38558.1 xref: UniProtKB:O95067 xref: UniProtKB:Q6FI99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004245 ! CCNB2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: participates_in CCO:I0006102 ! mcm2-ccnb2 direct interaction relationship: participates_in CCO:I0006149 ! cdkn1a-ccnb2 direct interaction relationship: participates_in CCO:I0006155 ! cdk2-ccnb2 direct interaction relationship: participates_in CCO:I0007900 ! cyclinb2_cdk1_human direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001447 name: REC8_HUMAN def: "Meiotic recombination protein REC8 homolog" [UniProtKB:O95072] synonym: "Cohesin Rec8p" EXACT [UniProtKB:O95072] xref: EMBL:AAD01193.1 xref: EMBL:AAH04159.1 xref: EMBL:AAH10887.1 xref: EMBL:AAH19326.1 xref: EMBL:BAA91690.1 xref: EMBL:CAG33544.1 xref: UniProtKB:O95072 xref: UniProtKB:Q6IA92 xref: UniProtKB:Q8WUV8 xref: UniProtKB:Q9BTF2 xref: UniProtKB:Q9NVQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005459 ! REC8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000127 ! lateral element relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000076 ! sister chromatid cohesion relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000695 ! chromosome segregation [Term] id: CCO:B0001448 name: TNF15_HUMAN def: "Tumor necrosis factor ligand superfamily member 15" [UniProtKB:O95150] synonym: "TNF ligand-related molecule 1" EXACT [UniProtKB:O95150] synonym: "Vascular endothelial cell growth inhibitor" EXACT [UniProtKB:O95150] xref: EMBL:AAD08783.1 xref: EMBL:AAH69435.1 xref: EMBL:AAH74940.1 xref: EMBL:AAH74941.1 xref: EMBL:AAI04463.1 xref: EMBL:AAI04464.1 xref: EMBL:AAM77366.1 xref: EMBL:AAR98573.1 xref: EMBL:BAF84331.1 xref: EMBL:CAH73730.1 xref: EMBL:CAH73731.1 xref: EMBL:EAW87431.1 xref: UniProtKB:O95150 xref: UniProtKB:Q3SX69 xref: UniProtKB:Q5VJK8 xref: UniProtKB:Q5VWH1 xref: UniProtKB:Q8NFE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005797 ! TNFSF15_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity [Term] id: CCO:B0001449 name: ZWINT_HUMAN def: "ZW10 interactor" [UniProtKB:O95229] synonym: "ZW10-interacting protein 1" EXACT [UniProtKB:O95229] synonym: "Zwint-1" EXACT [UniProtKB:O95229] xref: EMBL:AAC78629.1 xref: EMBL:AAH00411.1 xref: EMBL:AAH20979.1 xref: EMBL:AAI10400.1 xref: UniProtKB:O95229 xref: UniProtKB:Q0D2I3 xref: UniProtKB:Q9BWD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005975 ! ZWINT_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006066 ! kntc2_zwint_5 physical interaction relationship: participates_in CCO:I0006446 ! kntc2_zwint_6 colocalization relationship: participates_in CCO:I0006447 ! zw10_zwint_2 colocalization relationship: participates_in CCO:I0006448 ! zwint_mad2l1_1 colocalization relationship: participates_in CCO:I0006449 ! zwint_bub1b_1 colocalization relationship: participates_in CCO:I0006750 ! zwint_zw10_2 colocalization relationship: participates_in CCO:I0006755 ! kntc2_zwint_4 colocalization relationship: participates_in CCO:I0006756 ! zw10_zwint_1 colocalization relationship: participates_in CCO:I0006791 ! kntc2_zwint_1 physical interaction relationship: participates_in CCO:I0007157 ! kntc2_zwint_2 physical interaction relationship: participates_in CCO:I0007158 ! zwint_kntc2_2 physical interaction relationship: participates_in CCO:I0007159 ! kntc2_zwint_3 physical interaction relationship: participates_in CCO:I0007160 ! zw10_kntc2_1 physical interaction relationship: participates_in CCO:I0007161 ! zwint_kntc2_3 physical interaction relationship: participates_in CCO:I0007162 ! zw10_kntc2_2 physical interaction relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: participates_in CCO:I0007820 ! zwint_zw10_1 physical interaction relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001450 name: SMC2_HUMAN def: "Structural maintenance of chromosomes protein 2" [UniProtKB:O95347] synonym: "Chromosome-associated protein E" EXACT [UniProtKB:O95347] synonym: "hCAP-E" EXACT [UniProtKB:O95347] synonym: "XCAP-E homolog" EXACT [UniProtKB:O95347] xref: EMBL:AAC72360.1 xref: EMBL:AAF29579.1 xref: EMBL:AAI30386.1 xref: EMBL:CAD89875.1 xref: EMBL:CAI16866.1 xref: EMBL:CAI16923.1 xref: EMBL:CAI46187.1 xref: EMBL:EAW58973.1 xref: UniProtKB:O95347 xref: UniProtKB:Q6IEE0 xref: UniProtKB:Q9P1P2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005627 ! SMC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000123 ! condensin complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006360 ! ikbkg-smc2l1 physical interaction relationship: participates_in CCO:I0006602 ! disc1-smc2l1 physical interaction relationship: participates_in CCO:I0006930 ! smc2-hp1 colocalization relationship: participates_in CCO:I0007038 ! smc2l1-smc4l1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001451 name: YETS4_HUMAN def: "YEATS domain-containing protein 4" [UniProtKB:O95619] synonym: "Gas41" EXACT [UniProtKB:O95619] synonym: "Glioma-amplified sequence 41" EXACT [UniProtKB:O95619] synonym: "NuBI-1" EXACT [UniProtKB:O95619] synonym: "NuBI1" EXACT [UniProtKB:O95619] synonym: "NuMA-binding protein 1" EXACT [UniProtKB:O95619] xref: EMBL:AAD12188.1 xref: EMBL:AAH00994.1 xref: EMBL:BAA91678.1 xref: EMBL:CAC01935.1 xref: UniProtKB:O95619 xref: UniProtKB:Q9NQD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005950 ! YEATS4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006037 ! znf-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0007025 ! tacc1-yeats4-1 physical interaction relationship: participates_in CCO:I0007026 ! tacc1-yeats4-2 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007172 ! tacc1-yeats4-4 colocalization relationship: participates_in CCO:I0007315 ! tacc1-yeats4 physical interaction relationship: participates_in CCO:I0007507 ! yeats4-tacc1 physical interaction relationship: participates_in CCO:I0007508 ! tacc1-yeats4-3 colocalization relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007773 ! znf-ruvbl physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0001452 name: O95648_HUMAN def: "Septin" [UniProtKB:O95648] xref: EMBL:AAD00564.1 xref: UniProtKB:O95648 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001453 name: DIRA3_HUMAN def: "GTP-binding protein Di-Ras3" [UniProtKB:O95661] synonym: "Distinct subgroup of the Ras family member 3" EXACT [UniProtKB:O95661] synonym: "Rho-related GTP-binding protein RhoI" EXACT [UniProtKB:O95661] xref: EMBL:AAD03164.1 xref: EMBL:AAG35625.1 xref: EMBL:AAH05362.1 xref: EMBL:CAG46668.1 xref: EMBL:CAG46690.1 xref: EMBL:CAI21991.1 xref: UniProtKB:O95661 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004473 ! DIRAS3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000654 ! genetic imprinting relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0001454 name: LATS1_HUMAN def: "Serine/threonine-protein kinase LATS1" [UniProtKB:O95835] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O95835] synonym: "h-warts" EXACT [UniProtKB:O95835] synonym: "Large tumor suppressor homolog 1" EXACT [UniProtKB:O95835] synonym: "WARTS protein kinase" EXACT [UniProtKB:O95835] xref: EMBL:AAD16882.1 xref: EMBL:AAD50272.1 xref: EMBL:AAH02767.1 xref: UniProtKB:O95835 xref: UniProtKB:Q6PKD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004971 ! LATS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006610 ! lats1-limk1-3 physical interaction relationship: participates_in CCO:I0006849 ! lats1-cdc2-1 physical interaction relationship: participates_in CCO:I0006850 ! lats1-limk1-1 physical interaction relationship: participates_in CCO:I0006851 ! lats1-limk1-2 physical interaction relationship: participates_in CCO:I0006954 ! lats1-zyx-1 physical interaction relationship: participates_in CCO:I0007236 ! lats1-zyx-6 colocalization relationship: participates_in CCO:I0007237 ! lats1-limk1-5 colocalization relationship: participates_in CCO:I0007728 ! lats1-zyx-4 physical interaction relationship: participates_in CCO:I0007729 ! lats1-cdc2-2 physical interaction relationship: participates_in CCO:I0007730 ! lats1-limk1-4 physical interaction relationship: participates_in CCO:I0007950 ! lats1-zyx-2 physical interaction relationship: participates_in CCO:I0007951 ! lats1-zyx-3 physical interaction relationship: participates_in CCO:I0007952 ! lats1-zyx-5 physical interaction relationship: participates_in CCO:I0007953 ! lats1-zyx-7 physical interaction relationship: participates_in CCO:I0007958 ! lats1-zyx-8 physical interaction relationship: participates_in CCO:I0007959 ! lats1-zyx-9 physical interaction relationship: participates_in CCO:I0007960 ! lats1-zyx-10 physical interaction relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000054 ! sister chromatid segregation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012677 ! LATS1_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0012678 ! LATS1_HUMAN-Phosphoserine464 relationship: transforms_into CCO:B0012679 ! LATS1_HUMAN-Phosphoserine674 relationship: transforms_into CCO:B0012680 ! LATS1_HUMAN-Phosphoserine909 relationship: transforms_into CCO:B0012681 ! LATS1_HUMAN-Phosphothreonine1079 relationship: transforms_into CCO:B0048310 ! LATS1_HUMAN-Phosphotyrosine277 [Term] id: CCO:B0001455 name: RECK_HUMAN def: "Reversion-inducing cysteine-rich protein with Kazal motifs precursor" [UniProtKB:O95980] synonym: "hRECK" EXACT [UniProtKB:O95980] synonym: "ST15" EXACT [UniProtKB:O95980] synonym: "Suppressor of tumorigenicity 15" EXACT [UniProtKB:O95980] xref: EMBL:BAA34060.1 xref: EMBL:CAD13384.2 xref: EMBL:CAH70155.1 xref: UniProtKB:O95980 xref: UniProtKB:Q5W0K6 xref: UniProtKB:Q8WX37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005460 ! RECK_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001771 ! metalloendopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000051 ! peripheral to membrane of membrane fraction relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001457 name: PTTG1_HUMAN def: "Securin" [UniProtKB:O95997] synonym: "Esp1-associated protein" EXACT [UniProtKB:O95997] synonym: "hPTTG" EXACT [UniProtKB:O95997] synonym: "Pituitary tumor-transforming gene 1 protein" EXACT [UniProtKB:O95997] synonym: "Tumor-transforming protein 1" EXACT [UniProtKB:O95997] xref: EMBL:AAC64409.1 xref: EMBL:AAD19335.1 xref: EMBL:AAF06995.1 xref: EMBL:CAA11683.1 xref: UniProtKB:O95997 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005403 ! PTTG1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013650 ! PTTG1_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0048363 ! PTTG1_HUMAN-Phosphoserine102 [Term] id: CCO:B0001458 name: BCL10_HUMAN def: "B-cell lymphoma/leukemia 10" [UniProtKB:O95999] synonym: "B-cell CLL/lymphoma 10" EXACT [UniProtKB:O95999] synonym: "Bcl-10" EXACT [UniProtKB:O95999] synonym: "c-E10" EXACT [UniProtKB:O95999] synonym: "CARD-containing molecule enhancing NF-kappa-B" EXACT [UniProtKB:O95999] synonym: "CARD-like apoptotic protein" EXACT [UniProtKB:O95999] synonym: "cCARMEN" EXACT [UniProtKB:O95999] synonym: "CED-3/ICH-1 prodomain homologous E10-like regulator" EXACT [UniProtKB:O95999] synonym: "Cellular homolog of vCARMEN" EXACT [UniProtKB:O95999] synonym: "Cellular-E10" EXACT [UniProtKB:O95999] synonym: "CIPER" EXACT [UniProtKB:O95999] synonym: "hCLAP" EXACT [UniProtKB:O95999] synonym: "Mammalian CARD-containing adapter molecule E10" EXACT [UniProtKB:O95999] synonym: "mE10" EXACT [UniProtKB:O95999] xref: EMBL:AAC99767.1 xref: EMBL:AAD15800.1 xref: EMBL:AAD16428.1 xref: EMBL:AAD24918.1 xref: EMBL:AAD32597.1 xref: EMBL:AAD39147.1 xref: EMBL:AAF06894.1 xref: EMBL:AAH53617.1 xref: EMBL:CAA06955.1 xref: UniProtKB:O95999 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004150 ! BCL10_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004132 ! kinase activator activity relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_function CCO:F0005850 ! protein kinase B binding relationship: has_function CCO:F0005879 ! protein self-association relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001453 ! CBM complex relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0001962 ! lipopolysaccharide receptor complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:I0006342 ! bcl10-akt1-3 physical interaction relationship: participates_in CCO:I0006343 ! bcl10-bcl3-3 physical interaction relationship: participates_in CCO:I0007374 ! bcl10-akt1-4 physical interaction relationship: participates_in CCO:I0007795 ! bcl10-akt1-1 physical interaction relationship: participates_in CCO:I0007796 ! bcl10-akt1-2 physical interaction relationship: participates_in CCO:I0007797 ! bcl10-bcl3-1 physical interaction relationship: participates_in CCO:I0007798 ! bcl10-bcl3-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000535 ! toll-like receptor signaling pathway relationship: participates_in CCO:P0000616 ! negative regulation of mature B cell apoptosis relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0001432 ! positive regulation of protein ubiquitination relationship: participates_in CCO:P0002059 ! positive regulation of phosphorylation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002357 ! positive regulation of interleukin-8 biosynthetic process relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002974 ! regulation of T cell receptor signaling pathway relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0001459 name: CHK2_HUMAN def: "Serine/threonine-protein kinase Chk2" [UniProtKB:O96017] synonym: "Cds1" EXACT [UniProtKB:O96017] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O96017] xref: EMBL:AAC83693.1 xref: EMBL:AAD11784.1 xref: EMBL:AAD48504.1 xref: EMBL:AAH04207.1 xref: EMBL:AAS58456.1 xref: EMBL:AAS58457.1 xref: EMBL:AAS58458.1 xref: EMBL:AAS58459.1 xref: EMBL:AAS58460.1 xref: EMBL:AAS58461.1 xref: EMBL:AAS58462.1 xref: EMBL:AAS58463.1 xref: EMBL:AAS58464.1 xref: EMBL:AAS58465.1 xref: EMBL:AAS58466.1 xref: EMBL:AAV41895.1 xref: EMBL:BAB17231.1 xref: EMBL:CAA10319.1 xref: EMBL:CAG30304.1 xref: EMBL:CAH73823.1 xref: EMBL:CAH73875.1 xref: UniProtKB:O96017 xref: UniProtKB:Q6QA03 xref: UniProtKB:Q6QA04 xref: UniProtKB:Q6QA05 xref: UniProtKB:Q6QA06 xref: UniProtKB:Q6QA07 xref: UniProtKB:Q6QA08 xref: UniProtKB:Q6QA10 xref: UniProtKB:Q6QA11 xref: UniProtKB:Q6QA12 xref: UniProtKB:Q6QA13 xref: UniProtKB:Q9HCQ8 xref: UniProtKB:Q9UGF0 xref: UniProtKB:Q9UGF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004348 ! CHEK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:I0006254 ! chek2-aatf-2 phosphorylation relationship: participates_in CCO:I0006257 ! chek2-aatf-3 phosphorylation relationship: participates_in CCO:I0007041 ! chek2-aatf physical interaction relationship: participates_in CCO:I0007178 ! chek2-aatf-1 physical interaction relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: participates_in CCO:P0002125 ! DNA damage response, signal transduction relationship: transforms_into CCO:B0011217 ! CHK2_HUMAN-Phosphothreonine68 [Term] id: CCO:B0001460 name: CCNE2_HUMAN def: "G1/S-specific cyclin-E2" [UniProtKB:O96020] xref: EMBL:AAC78145.1 xref: EMBL:AAC80528.1 xref: EMBL:AAD08816.1 xref: EMBL:AAD08819.1 xref: EMBL:AAV97813.1 xref: UniProtKB:O95439 xref: UniProtKB:O96020 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004252 ! CCNE2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006107 ! orc3l-ccne2 direct interaction relationship: participates_in CCO:I0006127 ! cdk2-ccne2 direct interaction relationship: participates_in CCO:I0006132 ! cdkn1a-ccne2 direct interaction relationship: participates_in CCO:I0007908 ! cycline2_cdk2_human direct interaction relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010997 ! CCNE2_HUMAN-Phosphothreonine392 [Term] id: CCO:B0001461 name: ABL1_HUMAN def: "Proto-oncogene tyrosine-protein kinase ABL1" [UniProtKB:P00519] synonym: "Abelson murine leukemia viral oncogene homolog 1" EXACT [UniProtKB:P00519] synonym: "c-ABL" EXACT [UniProtKB:P00519] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P00519] synonym: "p150" EXACT [UniProtKB:P00519] xref: EMBL:AAA51561.1 xref: EMBL:AAB60393.1 xref: EMBL:AAB60394.1 xref: EMBL:AAD14034.1 xref: EMBL:AAZ38718.1 xref: EMBL:CAA34438.1 xref: UniProtKB:P00519 xref: UniProtKB:Q13869 xref: UniProtKB:Q13870 xref: UniProtKB:Q16133 xref: UniProtKB:Q45F09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004013 ! ABL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006071 ! abl1-rin1-3 physical interaction relationship: participates_in CCO:I0006203 ! abl1-ywhaz-1 physical interaction relationship: participates_in CCO:I0006204 ! abl1-snf-1 physical interaction relationship: participates_in CCO:I0006307 ! abl1-ywhab-1 physical interaction relationship: participates_in CCO:I0006728 ! abl1-sorbs-2 physical interaction relationship: participates_in CCO:I0006922 ! abl1-rin1-1 physical interaction relationship: participates_in CCO:I0006923 ! abl1-rin1-2 physical interaction relationship: participates_in CCO:I0006953 ! abi1-nckap1-1 physical interaction relationship: participates_in CCO:I0007069 ! abi1-abl1-2 physical interaction relationship: participates_in CCO:I0007171 ! abl1-rin1-4 phosphorylation relationship: participates_in CCO:I0007527 ! abi1-abl1-1 physical interaction relationship: participates_in CCO:I0007696 ! atm-cabl-1 physical interaction relationship: participates_in CCO:I0007751 ! abl1-sorbs-1 physical interaction relationship: participates_in CCO:I0007799 ! st5-abl1-1 physical interaction relationship: participates_in CCO:P0000025 ! S-phase-specific transcription in mitotic cell cycle relationship: participates_in CCO:P0000645 ! mismatch repair relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: transforms_into CCO:B0010398 ! ABL1_HUMAN-Phosphotyrosine185 relationship: transforms_into CCO:B0010399 ! ABL1_HUMAN-Phosphotyrosine226 relationship: transforms_into CCO:B0010400 ! ABL1_HUMAN-Phosphotyrosine253 relationship: transforms_into CCO:B0010401 ! ABL1_HUMAN-Phosphotyrosine257 relationship: transforms_into CCO:B0010402 ! ABL1_HUMAN-Phosphotyrosine264 relationship: transforms_into CCO:B0010403 ! ABL1_HUMAN-Phosphotyrosine393 relationship: transforms_into CCO:B0010404 ! ABL1_HUMAN-Phosphothreonine394 relationship: transforms_into CCO:B0010405 ! ABL1_HUMAN-Phosphoserine446 relationship: transforms_into CCO:B0010406 ! ABL1_HUMAN-Phosphotyrosine469 relationship: transforms_into CCO:B0010407 ! ABL1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0010408 ! ABL1_HUMAN-Phosphoserine683 relationship: transforms_into CCO:B0010409 ! ABL1_HUMAN-Phosphoserine805 relationship: transforms_into CCO:B0010410 ! ABL1_HUMAN-Phosphoserine809 relationship: transforms_into CCO:B0010411 ! ABL1_HUMAN-Phosphoserine949 [Term] id: CCO:B0001462 name: EGFR_HUMAN def: "Epidermal growth factor receptor precursor" [UniProtKB:P00533] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P00533] synonym: "Receptor tyrosine-protein kinase ErbB-1" EXACT [UniProtKB:P00533] xref: EMBL:AAA52370.1 xref: EMBL:AAA63171.1 xref: EMBL:AAB53063.1 xref: EMBL:AAC50796.1 xref: EMBL:AAC50797.1 xref: EMBL:AAC50798.1 xref: EMBL:AAC50799.1 xref: EMBL:AAC50800.1 xref: EMBL:AAC50801.1 xref: EMBL:AAC50802.1 xref: EMBL:AAC50804.1 xref: EMBL:AAG35786.1 xref: EMBL:AAG35787.1 xref: EMBL:AAG35788.1 xref: EMBL:AAG35789.1 xref: EMBL:AAG35790.1 xref: EMBL:AAG43240.1 xref: EMBL:AAG43243.1 xref: EMBL:AAK01080.1 xref: EMBL:AAS83109.1 xref: EMBL:CAA25240.1 xref: EMBL:CAA25282.1 xref: EMBL:CAA29668.1 xref: UniProtKB:O00688 xref: UniProtKB:O00732 xref: UniProtKB:P00533 xref: UniProtKB:P06268 xref: UniProtKB:Q14225 xref: UniProtKB:Q92795 xref: UniProtKB:Q9BZS2 xref: UniProtKB:Q9GZX1 xref: UniProtKB:Q9H2C9 xref: UniProtKB:Q9H3C9 xref: UniProtKB:Q9UMD7 xref: UniProtKB:Q9UMD8 xref: UniProtKB:Q9UMG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004552 ! EGFR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005972 ! egf-egfr-2 direct interaction relationship: participates_in CCO:I0006214 ! rabgef1-egfr physical interaction relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0006278 ! egfr-grb2 physical interaction relationship: participates_in CCO:I0006282 ! ywhaz-egfr-1 physical interaction relationship: participates_in CCO:I0006444 ! erbb2-egfr physical interaction relationship: participates_in CCO:I0006445 ! erbb2-egfr-1 physical interaction relationship: participates_in CCO:I0006532 ! egf-egfr-1 direct interaction relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0006842 ! egfr-grb2-1 physical interaction relationship: participates_in CCO:I0006978 ! egfr-pik3c2b-2 physical interaction relationship: participates_in CCO:I0006979 ! egfr-pik3c2b-5 physical interaction relationship: participates_in CCO:I0007122 ! egfr-cbl1-1 direct interaction relationship: participates_in CCO:I0007123 ! egfr-cbl1-4 direct interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007167 ! egfr-tgfa-1 direct interaction relationship: participates_in CCO:I0007197 ! egfr-h3fa-1 colocalization relationship: participates_in CCO:I0007198 ! egfr-cd59-1 direct interaction relationship: participates_in CCO:I0007304 ! erbb2-egfr-2 physical interaction relationship: participates_in CCO:I0007305 ! erbb2-egfr-3 physical interaction relationship: participates_in CCO:I0007365 ! erbb1-erbb3-2 physical interaction relationship: participates_in CCO:I0007366 ! erbb1-erbb4-2 physical interaction relationship: participates_in CCO:I0007428 ! egfr-pik3c2b-3 direct interaction relationship: participates_in CCO:I0007429 ! egfr-pik3c2b-6 direct interaction relationship: participates_in CCO:I0007453 ! gab2-grb2-1 physical interaction relationship: participates_in CCO:I0007503 ! egf-egfr-3 direct interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:I0007570 ! egfr-pik3c2b-4 physical interaction relationship: participates_in CCO:I0007591 ! erbb1-erbb2-1 physical interaction relationship: participates_in CCO:I0007592 ! erbb1-erbb3-1 physical interaction relationship: participates_in CCO:I0007593 ! erbb1-erbb4-1 physical interaction relationship: participates_in CCO:I0007817 ! erbb2-egfr-4 physical interaction relationship: participates_in CCO:I0007845 ! ywhaz-egfr-2 colocalization relationship: participates_in CCO:I0007877 ! egfr-pik3c2a-1 physical interaction relationship: participates_in CCO:I0007878 ! egfr-pik3c2b-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0008360 ! atp5c1-egfr physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002059 ! positive regulation of phosphorylation relationship: participates_in CCO:P0002136 ! calcium-dependent phospholipase A2 activation relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: participates_in CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation relationship: transforms_into CCO:B0011651 ! EGFR_HUMAN-Phosphothreonine678 relationship: transforms_into CCO:B0011652 ! EGFR_HUMAN-Phosphothreonine693 relationship: transforms_into CCO:B0011653 ! EGFR_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0011654 ! EGFR_HUMAN-Phosphotyrosine978 relationship: transforms_into CCO:B0011655 ! EGFR_HUMAN-Phosphoserine991 relationship: transforms_into CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: transforms_into CCO:B0011657 ! EGFR_HUMAN-Phosphotyrosine998 relationship: transforms_into CCO:B0011658 ! EGFR_HUMAN-Phosphoserine1026 relationship: transforms_into CCO:B0011659 ! EGFR_HUMAN-Phosphoserine1064 relationship: transforms_into CCO:B0011660 ! EGFR_HUMAN-Phosphotyrosine1069 relationship: transforms_into CCO:B0011661 ! EGFR_HUMAN-Phosphoserine1070 relationship: transforms_into CCO:B0011662 ! EGFR_HUMAN-Phosphoserine1071 relationship: transforms_into CCO:B0011663 ! EGFR_HUMAN-Phosphotyrosine1092 relationship: transforms_into CCO:B0011664 ! EGFR_HUMAN-Phosphotyrosine1110 relationship: transforms_into CCO:B0011665 ! EGFR_HUMAN-Phosphotyrosine1138 relationship: transforms_into CCO:B0011666 ! EGFR_HUMAN-Phosphoserine1166 relationship: transforms_into CCO:B0011667 ! EGFR_HUMAN-Phosphotyrosine1172 relationship: transforms_into CCO:B0011668 ! EGFR_HUMAN-Phosphotyrosine1197 relationship: transforms_into CCO:B0064931 ! EGFR_HUMAN-Phosphotyrosine869 [Term] id: CCO:B0001464 name: THRB_HUMAN def: "Prothrombin precursor" [UniProtKB:P00734] synonym: "Coagulation factor II" EXACT [UniProtKB:P00734] synonym: "EC 3.4.21.5" EXACT [UniProtKB:P00734] xref: EMBL:AAC63054.1 xref: EMBL:AAL77436.1 xref: EMBL:CAA23842.1 xref: UniProtKB:P00734 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005780 ! F2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006635 ! thbd-f2-1 direct interaction relationship: participates_in CCO:I0006636 ! thbd-f2-2 direct interaction relationship: participates_in CCO:I0006637 ! thbd-f2-3 direct interaction relationship: participates_in CCO:I0006638 ! thbd-f2-4 direct interaction relationship: participates_in CCO:I0006675 ! gp1ba-f2 physical interaction relationship: participates_in CCO:I0007168 ! f2-f2-1 physical interaction relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000777 ! tyrosine phosphorylation of STAT protein relationship: participates_in CCO:P0000779 ! STAT protein nuclear translocation relationship: participates_in CCO:P0001742 ! positive regulation of collagen biosynthetic process relationship: transforms_into CCO:B0014352 ! THRB_HUMAN-4-carboxyglutamate49 relationship: transforms_into CCO:B0014353 ! THRB_HUMAN-4-carboxyglutamate50 relationship: transforms_into CCO:B0014354 ! THRB_HUMAN-4-carboxyglutamate57 relationship: transforms_into CCO:B0014355 ! THRB_HUMAN-4-carboxyglutamate59 relationship: transforms_into CCO:B0014356 ! THRB_HUMAN-4-carboxyglutamate62 relationship: transforms_into CCO:B0014357 ! THRB_HUMAN-4-carboxyglutamate63 relationship: transforms_into CCO:B0014358 ! THRB_HUMAN-4-carboxyglutamate68 relationship: transforms_into CCO:B0014359 ! THRB_HUMAN-4-carboxyglutamate69 relationship: transforms_into CCO:B0014360 ! THRB_HUMAN-4-carboxyglutamate72 relationship: transforms_into CCO:B0014361 ! THRB_HUMAN-4-carboxyglutamate75 [Term] id: CCO:B0001465 name: MYC_HUMAN def: "Myc proto-oncogene protein" [UniProtKB:P01106] synonym: "c-Myc" EXACT [UniProtKB:P01106] synonym: "Transcription factor p64" EXACT [UniProtKB:P01106] xref: EMBL:AAA36340.1 xref: EMBL:AAA59880.1 xref: EMBL:AAA59881.1 xref: EMBL:AAA59882.1 xref: EMBL:AAA88092.1 xref: EMBL:AAH00141.2 xref: EMBL:AAH00917.2 xref: EMBL:AAH58901.2 xref: EMBL:AAO21131.1 xref: EMBL:AAV38573.1 xref: EMBL:BAA01374.2 xref: EMBL:BAA01375.1 xref: EMBL:CAA23831.1 xref: EMBL:CAA25015.2 xref: EMBL:CAA25106.1 xref: EMBL:CAA25288.1 xref: UniProtKB:P01106 xref: UniProtKB:P01107 xref: UniProtKB:Q14026 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005142 ! MYC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005980 ! snip1-myc-2 physical interaction relationship: participates_in CCO:I0005981 ! myc-snip1-1 physical interaction relationship: participates_in CCO:I0005982 ! max-myc-4 physical interaction relationship: participates_in CCO:I0005983 ! snip1-myc-4 physical interaction relationship: participates_in CCO:I0006463 ! snip1-myc-1 physical interaction relationship: participates_in CCO:I0006607 ! snip1-myc physical interaction relationship: participates_in CCO:I0006703 ! trrap-myc-2 physical interaction relationship: participates_in CCO:I0006784 ! myc-snip1 physical interaction relationship: participates_in CCO:I0006785 ! myc-skp2 physical interaction relationship: participates_in CCO:I0006786 ! myc-fbxw7 physical interaction relationship: participates_in CCO:I0006787 ! myc-ep300 physical interaction relationship: participates_in CCO:I0006934 ! snip1-myc-3 physical interaction relationship: participates_in CCO:I0006935 ! myc-snip1-2 physical interaction relationship: participates_in CCO:I0007005 ! myc-zbtb17-1 physical interaction relationship: participates_in CCO:I0007006 ! myc-zbtb17-2 physical interaction relationship: participates_in CCO:I0007007 ! myc-max physical interaction relationship: participates_in CCO:I0007076 ! trrap-myc-1 physical interaction relationship: participates_in CCO:I0007187 ! myc-snip1-3 physical interaction relationship: participates_in CCO:I0007188 ! myc-skp2-1 physical interaction relationship: participates_in CCO:I0007969 ! myc-nmi-1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013057 ! MYC_HUMAN-Phosphothreonine8 relationship: transforms_into CCO:B0013058 ! MYC_HUMAN-Phosphothreonine58 relationship: transforms_into CCO:B0013059 ! MYC_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0013060 ! MYC_HUMAN-N6-acetyllysine143 relationship: transforms_into CCO:B0013061 ! MYC_HUMAN-N6-acetyllysine157 relationship: transforms_into CCO:B0013062 ! MYC_HUMAN-N6-acetyllysine275 relationship: transforms_into CCO:B0013063 ! MYC_HUMAN-N6-acetyllysine317 relationship: transforms_into CCO:B0013064 ! MYC_HUMAN-N6-acetyllysine323 relationship: transforms_into CCO:B0013065 ! MYC_HUMAN-N6-acetyllysine371 [Term] id: CCO:B0001466 name: RASN_HUMAN def: "GTPase NRas precursor" [UniProtKB:P01111] synonym: "Transforming protein N-Ras" EXACT [UniProtKB:P01111] xref: EMBL:AAA36548.1 xref: EMBL:AAA36556.1 xref: EMBL:AAA60255.1 xref: EMBL:AAH05219.1 xref: EMBL:AAM12633.1 xref: EMBL:AAQ94397.1 xref: EMBL:CAA25269.1 xref: EMBL:CAA25270.1 xref: EMBL:CAA25271.1 xref: EMBL:CAA25272.1 xref: EMBL:CAA26529.1 xref: EMBL:CAA29079.1 xref: EMBL:CAA30320.1 xref: EMBL:CAA37384.1 xref: UniProtKB:P01111 xref: UniProtKB:Q14971 xref: UniProtKB:Q15104 xref: UniProtKB:Q15282 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005435 ! NRAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001566 ! regulation of synaptic transmission, GABAergic relationship: participates_in CCO:P0001984 ! positive regulation of Rac protein signal transduction relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0002786 ! regulation of long-term neuronal synaptic plasticity relationship: transforms_into CCO:B0013717 ! RASN_HUMAN-Cysteine methyl ester186 [Term] id: CCO:B0001467 name: RASH_HUMAN def: "GTPase HRas precursor" [UniProtKB:P01112] synonym: "c-H-ras" EXACT [UniProtKB:P01112] synonym: "H-Ras-1" EXACT [UniProtKB:P01112] synonym: "Ha-Ras" EXACT [UniProtKB:P01112] synonym: "p21ras" EXACT [UniProtKB:P01112] synonym: "Transforming protein p21" EXACT [UniProtKB:P01112] xref: EMBL:AAA35685.1 xref: EMBL:AAB02605.1 xref: EMBL:AAH95471.1 xref: EMBL:AAM12630.1 xref: EMBL:AAV38228.1 xref: EMBL:BAG70150.1 xref: EMBL:BAG70299.1 xref: EMBL:CAG38816.1 xref: EMBL:CAG47067.1 xref: EMBL:EAX02337.1 xref: UniProtKB:B5BUA0 xref: UniProtKB:P01112 xref: UniProtKB:Q14080 xref: UniProtKB:Q6FHV9 xref: UniProtKB:Q9UCE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005433 ! HRAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005970 ! hras-pik3cg-1 direct interaction relationship: participates_in CCO:I0006069 ! hras-sos1-6 direct interaction relationship: participates_in CCO:I0006268 ! brap-hras-2 physical interaction relationship: participates_in CCO:I0006450 ! hras-sos1-1 direct interaction relationship: participates_in CCO:I0006478 ! rlg1-hras physical interaction relationship: participates_in CCO:I0006678 ! hras-brap physical interaction relationship: participates_in CCO:I0006709 ! raf1-hras-2 physical interaction relationship: participates_in CCO:I0006924 ! abl2-rin1-5 physical interaction relationship: participates_in CCO:I0007001 ! hras1-rassf5-2 physical interaction relationship: participates_in CCO:I0007170 ! abl2-rin1-4 physical interaction relationship: participates_in CCO:I0007280 ! raf1-hras-3 physical interaction relationship: participates_in CCO:I0007383 ! shoc2-erbb2ip-3 physical interaction relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0007472 ! rin1-hras-3 physical interaction relationship: participates_in CCO:I0007553 ! araf-hras physical interaction relationship: participates_in CCO:I0007708 ! hras-rasa1-1 direct interaction relationship: participates_in CCO:I0007724 ! brap-hras physical interaction relationship: participates_in CCO:I0007740 ! raf1-hras physical interaction relationship: participates_in CCO:I0007831 ! rin1-hras-1 physical interaction relationship: participates_in CCO:I0007832 ! rin1-hras-2 physical interaction relationship: participates_in CCO:I0007833 ! rin1-hras-4 physical interaction relationship: participates_in CCO:I0007834 ! raf1-hras-4 physical interaction relationship: participates_in CCO:I0007859 ! raf1-hras-1 physical interaction relationship: participates_in CCO:I0007937 ! hras-sos1-2 direct interaction relationship: participates_in CCO:I0007938 ! hras-sos1-3 direct interaction relationship: participates_in CCO:I0007939 ! hras-sos1-4 direct interaction relationship: participates_in CCO:I0007940 ! hras-sos1-5 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0013715 ! RASH_HUMAN-Cysteine methyl ester186 relationship: transforms_into CCO:B0041173 ! RASH_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0041174 ! RASH_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0048370 ! RASH_HUMAN-S-nitrosocysteine118 [Term] id: CCO:B0001468 name: RASK_HUMAN def: "GTPase KRas precursor" [UniProtKB:P01116] synonym: "c-K-ras" EXACT [UniProtKB:P01116] synonym: "c-Ki-ras" EXACT [UniProtKB:P01116] synonym: "K-Ras 2" EXACT [UniProtKB:P01116] synonym: "Ki-Ras" EXACT [UniProtKB:P01116] xref: EMBL:AAA35683.1 xref: EMBL:AAA36149.1 xref: EMBL:AAA36554.1 xref: EMBL:AAA36557.1 xref: EMBL:AAB41942.1 xref: EMBL:AAB59444.1 xref: EMBL:AAB59445.1 xref: EMBL:AAH13572.1 xref: EMBL:AAM12631.1 xref: EMBL:AAP35817.1 xref: EMBL:CAA25828.1 xref: EMBL:CAA26593.1 xref: UniProtKB:P01116 xref: UniProtKB:P01118 xref: UniProtKB:Q96D10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005434 ! KRAS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005809 ! hnrpc-kras physical interaction relationship: participates_in CCO:I0007375 ! kras-rassf2-1 physical interaction relationship: participates_in CCO:I0007412 ! krs-rassf2-2 direct interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001566 ! regulation of synaptic transmission, GABAergic relationship: participates_in CCO:P0001984 ! positive regulation of Rac protein signal transduction relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0002786 ! regulation of long-term neuronal synaptic plasticity relationship: transforms_into CCO:B0013716 ! RASK_HUMAN-ester186 relationship: transforms_into CCO:B0041175 ! RASK_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0041176 ! RASK_HUMAN-N-acetylthreonine2 [Term] id: CCO:B0001469 name: PDGFB_HUMAN def: "Platelet-derived growth factor subunit B precursor" [UniProtKB:P01127] synonym: "Becaplermin" EXACT [UniProtKB:P01127] synonym: "c-sis" EXACT [UniProtKB:P01127] synonym: "PDGF subunit B" EXACT [UniProtKB:P01127] synonym: "PDGF-2" EXACT [UniProtKB:P01127] synonym: "Platelet-derived growth factor B chain" EXACT [UniProtKB:P01127] synonym: "Platelet-derived growth factor beta polypeptide" EXACT [UniProtKB:P01127] xref: EMBL:AAA60552.1 xref: EMBL:AAA60553.1 xref: EMBL:AAA98793.1 xref: EMBL:AAH29822.1 xref: EMBL:AAH77725.1 xref: EMBL:CAA25228.1 xref: EMBL:CAA25229.1 xref: EMBL:CAA26524.1 xref: EMBL:CAA26579.1 xref: EMBL:CAA27333.1 xref: EMBL:CAA67262.1 xref: EMBL:CAB02635.1 xref: EMBL:CAG30424.1 xref: UniProtKB:P01127 xref: UniProtKB:P78431 xref: UniProtKB:Q9UF23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005288 ! PDGFB_human relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005862 ! cell surface binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007337 ! platelet-derived growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001126 ! platelet dense granule lumen relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000958 ! negative regulation of phosphatidylinositol biosynthetic process relationship: participates_in CCO:P0000975 ! negative regulation of platelet activation relationship: participates_in CCO:P0001108 ! positive regulation of smooth muscle cell migration relationship: participates_in CCO:P0002237 ! positive regulation of blood vessel endothelial cell migration relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation [Term] id: CCO:B0001470 name: EGF_HUMAN def: "Pro-epidermal growth factor precursor" [UniProtKB:P01133] synonym: "EGF" EXACT [UniProtKB:P01133] xref: EMBL:AAH93731.1 xref: EMBL:AAI13462.1 xref: EMBL:AAR84237.1 xref: EMBL:CAA28240.1 xref: UniProtKB:P01133 xref: UniProtKB:Q52LZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004553 ! EGF_human relationship: has_function CCO:F0001456 ! epidermal growth factor receptor binding relationship: has_function CCO:F0001457 ! epidermal growth factor receptor activating ligand activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:I0005972 ! egf-egfr-2 direct interaction relationship: participates_in CCO:I0006532 ! egf-egfr-1 direct interaction relationship: participates_in CCO:I0007503 ! egf-egfr-3 direct interaction relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000410 ! activation of MAPKK activity relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001212 ! positive regulation of granule cell precursor proliferation relationship: participates_in CCO:P0002059 ! positive regulation of phosphorylation relationship: participates_in CCO:P0002529 ! positive regulation of epidermal growth factor receptor activity relationship: participates_in CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0001471 name: TGFB1_HUMAN def: "Transforming growth factor beta-1 precursor" [UniProtKB:P01137] synonym: "TGF-beta-1" EXACT [UniProtKB:P01137] xref: EMBL:AAA36735.1 xref: EMBL:AAH00125.1 xref: EMBL:AAH01180.1 xref: EMBL:AAH22242.1 xref: EMBL:AAP35909.1 xref: EMBL:CAA26580.1 xref: EMBL:CAA29283.1 xref: UniProtKB:P01137 xref: UniProtKB:Q9UCG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005773 ! TGFB1_human relationship: has_function CCO:F0001462 ! transforming growth factor beta receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000377 ! Golgi lumen relationship: located_in CCO:C0000985 ! secretory granule relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:I0006333 ! tgfb1-bapp-1 physical interaction relationship: participates_in CCO:I0007784 ! tgfb1-tgfb2-bapp-2 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000177 ! positive regulation of exit from mitosis relationship: participates_in CCO:P0000188 ! G1/S transition checkpoint relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000724 ! SMAD protein nuclear translocation relationship: participates_in CCO:P0000794 ! negative regulation of neuroblast proliferation relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001742 ! positive regulation of collagen biosynthetic process relationship: participates_in CCO:P0002020 ! positive regulation of protein amino acid dephosphorylation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002809 ! positive regulation of isotype switching to IgA isotypes relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: participates_in CCO:P0002943 ! negative regulation of phagocytosis relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0003075 ! negative regulation of release of sequestered calcium ion into cytosol [Term] id: CCO:B0001472 name: IGF2_HUMAN def: "Insulin-like growth factor II precursor" [UniProtKB:P01344] synonym: "IGF-II" EXACT [UniProtKB:P01344] synonym: "Somatomedin-A" EXACT [UniProtKB:P01344] xref: EMBL:AAA52443.1 xref: EMBL:AAA52536.1 xref: EMBL:AAA52544.1 xref: EMBL:AAA52545.1 xref: EMBL:AAA60088.1 xref: EMBL:AAB34155.1 xref: EMBL:AAG17220.1 xref: EMBL:AAH00531.1 xref: EMBL:AAM51825.1 xref: EMBL:AAP35659.1 xref: EMBL:ABD93451.1 xref: EMBL:CAA25426.1 xref: EMBL:CAA27155.1 xref: EMBL:CAA27156.1 xref: EMBL:CAA27157.1 xref: EMBL:CAA27249.1 xref: EMBL:CAA29516.1 xref: EMBL:CAA29517.1 xref: EMBL:CAA29518.1 xref: EMBL:CAA30717.1 xref: UniProtKB:P01344 xref: UniProtKB:P78449 xref: UniProtKB:Q14299 xref: UniProtKB:Q1WM26 xref: UniProtKB:Q9UC68 xref: UniProtKB:Q9UC69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004868 ! IGF2_human relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000654 ! genetic imprinting relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001644 ! regulation of gene-specific transcription [Term] id: CCO:B0001473 name: TNFB_HUMAN def: "Lymphotoxin-alpha precursor" [UniProtKB:P01374] synonym: "LT-alpha" EXACT [UniProtKB:P01374] synonym: "TNF-beta" EXACT [UniProtKB:P01374] synonym: "Tumor necrosis factor ligand superfamily member 1" EXACT [UniProtKB:P01374] xref: EMBL:AAA61199.1 xref: EMBL:AAB59455.1 xref: EMBL:AAD18092.1 xref: EMBL:AAH34729.1 xref: EMBL:AAL49956.1 xref: EMBL:AAO21135.1 xref: EMBL:BAA00064.1 xref: EMBL:BAA02139.1 xref: EMBL:BAB63397.1 xref: EMBL:CAA00536.1 xref: EMBL:CAA25649.1 xref: EMBL:CAA26670.1 xref: EMBL:CAA75071.1 xref: EMBL:CAA78746.1 xref: UniProtKB:P01374 xref: UniProtKB:Q8N4C3 xref: UniProtKB:Q9UKS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005799 ! LTA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006964 ! hvem-lt_alpha physical interaction relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis relationship: participates_in CCO:P0002960 ! positive regulation of synaptic transmission [Term] id: CCO:B0001474 name: TNFA_HUMAN def: "Tumor necrosis factor precursor" [UniProtKB:P01375] synonym: "Cachectin" EXACT [UniProtKB:P01375] synonym: "TNF-a" EXACT [UniProtKB:P01375] synonym: "TNF-alpha" EXACT [UniProtKB:P01375] synonym: "Tumor necrosis factor ligand superfamily member 2" EXACT [UniProtKB:P01375] xref: EMBL:AAA36758.1 xref: EMBL:AAA61198.1 xref: EMBL:AAA61200.1 xref: EMBL:AAC03542.1 xref: EMBL:AAD18091.1 xref: EMBL:AAF71992.1 xref: EMBL:AAH28148.1 xref: EMBL:AAL47581.1 xref: EMBL:AAO21132.1 xref: EMBL:BAB63396.1 xref: EMBL:BAC54944.1 xref: EMBL:CAA25650.1 xref: EMBL:CAA26669.1 xref: EMBL:CAA75070.1 xref: EMBL:CAA78745.1 xref: UniProtKB:O43647 xref: UniProtKB:P01375 xref: UniProtKB:Q9P1Q2 xref: UniProtKB:Q9UIV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005798 ! TNF_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000187 ! phagocytic cup relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002022 ! recycling endosome relationship: participates_in CCO:I0006441 ! tnfrsf1a-tnf physical interaction relationship: participates_in CCO:I0006443 ! tnfrsf1b-tnf physical interaction relationship: participates_in CCO:I0006858 ! tnf-tnfrsf1a-2 physical interaction relationship: participates_in CCO:I0006859 ! tnf-tnfrsf1a-3 physical interaction relationship: participates_in CCO:I0006860 ! tnf-tnfrsf1a-4 physical interaction relationship: participates_in CCO:I0007246 ! tnf-tnfrsf1a-1 direct interaction relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0001810 ! tumor necrosis factor-mediated signaling pathway relationship: participates_in CCO:P0002161 ! regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis relationship: participates_in CCO:P0002272 ! positive regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002484 ! regulation of osteoclast differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002665 ! positive regulation of translational initiation by iron relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0002960 ! positive regulation of synaptic transmission relationship: participates_in CCO:P0003022 ! positive regulation of transcription factor activity relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0014420 ! TNFA_HUMAN-Phosphoserine2 [Term] id: CCO:B0001475 name: IL1A_HUMAN def: "Interleukin-1 alpha precursor" [UniProtKB:P01583] synonym: "Hematopoietin-1" EXACT [UniProtKB:P01583] synonym: "IL-1 alpha" EXACT [UniProtKB:P01583] xref: EMBL:AAA59133.1 xref: EMBL:AAA59134.1 xref: EMBL:AAH13142.1 xref: EMBL:AAM96189.1 xref: EMBL:AAP35660.1 xref: EMBL:CAA26371.1 xref: EMBL:CAA26604.1 xref: EMBL:CAA27448.1 xref: EMBL:CAA39566.1 xref: EMBL:CAD29871.1 xref: EMBL:CAG33695.1 xref: UniProtKB:P01583 xref: UniProtKB:Q7RU02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004878 ! IL1A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001451 ! interleukin-1 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001476 name: IL1B_HUMAN def: "Interleukin-1 beta precursor" [UniProtKB:P01584] synonym: "Catabolin" EXACT [UniProtKB:P01584] synonym: "IL-1 beta" EXACT [UniProtKB:P01584] xref: EMBL:AAA36106.1 xref: EMBL:AAA59135.1 xref: EMBL:AAA59136.1 xref: EMBL:AAA74137.1 xref: EMBL:AAH08678.1 xref: EMBL:AAM88883.1 xref: EMBL:AAP35877.1 xref: EMBL:AAX88888.1 xref: EMBL:CAA26372.1 xref: EMBL:CAA28185.1 xref: EMBL:CAA39567.1 xref: EMBL:CAD29872.1 xref: EMBL:CAG28607.1 xref: EMBL:EAW73605.1 xref: UniProtKB:P01584 xref: UniProtKB:Q53X59 xref: UniProtKB:Q53XX2 xref: UniProtKB:Q7M4S7 xref: UniProtKB:Q7RU01 xref: UniProtKB:Q96HE5 xref: UniProtKB:Q9UCT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004879 ! IL1B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001451 ! interleukin-1 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0005969 ! il1b-il1r1-1 direct interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002161 ! regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002272 ! positive regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002351 ! positive regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0003022 ! positive regulation of transcription factor activity [Term] id: CCO:B0001477 name: IL2RA_HUMAN def: "Interleukin-2 receptor alpha chain precursor" [UniProtKB:P01589] synonym: "CD25 antigen" EXACT [UniProtKB:P01589] synonym: "IL-2 receptor alpha subunit" EXACT [UniProtKB:P01589] synonym: "IL-2-RA" EXACT [UniProtKB:P01589] synonym: "IL2-RA" EXACT [UniProtKB:P01589] synonym: "p55" EXACT [UniProtKB:P01589] synonym: "TAC antigen" EXACT [UniProtKB:P01589] xref: EMBL:AAA59162.1 xref: EMBL:AAA67527.1 xref: EMBL:AAB59535.1 xref: EMBL:AAS55572.1 xref: EMBL:CAA25525.1 xref: EMBL:CAA26906.1 xref: UniProtKB:P01589 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004882 ! IL2RA_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001258 ! interleukin-2 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001479 name: ANXA1_HUMAN def: "Annexin A1" [UniProtKB:P04083] synonym: "Annexin I" EXACT [UniProtKB:P04083] synonym: "Annexin-1" EXACT [UniProtKB:P04083] synonym: "Calpactin II" EXACT [UniProtKB:P04083] synonym: "Chromobindin-9" EXACT [UniProtKB:P04083] synonym: "Lipocortin I" EXACT [UniProtKB:P04083] synonym: "p35" EXACT [UniProtKB:P04083] synonym: "Phospholipase A2 inhibitory protein" EXACT [UniProtKB:P04083] xref: EMBL:AAH01275.1 xref: EMBL:AAH35993.1 xref: EMBL:CAA29338.1 xref: UniProtKB:P04083 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004068 ! ANXA1_human relationship: has_function CCO:F0001215 ! phospholipase inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_function CCO:F0004187 ! phospholipase A2 inhibitor activity relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000170 ! cornified envelope relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0001638 ! sarcolemma relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0006356 ! nfkbia-anxa1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: transforms_into CCO:B0010550 ! ANXA1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0010551 ! ANXA1_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0010552 ! ANXA1_HUMAN-Phosphotyrosine21 relationship: transforms_into CCO:B0010553 ! ANXA1_HUMAN-Phosphothreonine24 relationship: transforms_into CCO:B0010554 ! ANXA1_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0010555 ! ANXA1_HUMAN-Phosphotyrosine207 relationship: transforms_into CCO:B0065649 ! ANXA1_HUMAN-Phosphotyrosine39 [Term] id: CCO:B0001480 name: PDGFA_HUMAN def: "Platelet-derived growth factor subunit A precursor" [UniProtKB:P04085] synonym: "PDGF subunit A" EXACT [UniProtKB:P04085] synonym: "PDGF-1" EXACT [UniProtKB:P04085] synonym: "Platelet-derived growth factor A chain" EXACT [UniProtKB:P04085] synonym: "Platelet-derived growth factor alpha polypeptide" EXACT [UniProtKB:P04085] xref: EMBL:AAA60045.1 xref: EMBL:AAA60046.1 xref: EMBL:AAA60047.1 xref: EMBL:AAB26566.1 xref: EMBL:CAA00830.1 xref: EMBL:CAA27421.1 xref: EMBL:CAA29677.1 xref: UniProtKB:P04085 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005287 ! PDGFA_human relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005862 ! cell surface binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007337 ! platelet-derived growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001126 ! platelet dense granule lumen relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000958 ! negative regulation of phosphatidylinositol biosynthetic process relationship: participates_in CCO:P0000975 ! negative regulation of platelet activation relationship: participates_in CCO:P0001107 ! regulation of smooth muscle cell migration relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation [Term] id: CCO:B0001481 name: HSP1_HUMAN def: "Sperm protamine-P1" [UniProtKB:P04553] synonym: "Cysteine-rich protamine" EXACT [UniProtKB:P04553] xref: EMBL:AAA60191.1 xref: EMBL:AAA63249.1 xref: EMBL:AAB29321.2 xref: EMBL:AAC50486.1 xref: EMBL:AAF34620.1 xref: EMBL:AAH03673.1 xref: EMBL:AAP35392.1 xref: EMBL:CAA68499.1 xref: EMBL:CAA87065.1 xref: UniProtKB:P04553 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004833 ! PRM1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation [Term] id: CCO:B0001482 name: PRM2_HUMAN def: "Protamine-2" [UniProtKB:P04554] synonym: "Sperm histone P2" EXACT [UniProtKB:P04554] synonym: "Sperm protamine-P2" EXACT [UniProtKB:P04554] xref: EMBL:AAA63250.1 xref: EMBL:AAC50487.1 xref: EMBL:AAF34632.1 xref: EMBL:AAH05303.1 xref: EMBL:AAH66338.1 xref: EMBL:CAA30710.1 xref: EMBL:CAA87066.1 xref: UniProtKB:P04554 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005378 ! PRM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation [Term] id: CCO:B0001483 name: P53_HUMAN def: "Cellular tumor antigen p53" [UniProtKB:P04637] synonym: "Antigen NY-CO-13" EXACT [UniProtKB:P04637] synonym: "Phosphoprotein p53" EXACT [UniProtKB:P04637] synonym: "Tumor suppressor p53" EXACT [UniProtKB:P04637] xref: EMBL:AAA59987.1 xref: EMBL:AAA59988.1 xref: EMBL:AAA59989.1 xref: EMBL:AAA61211.1 xref: EMBL:AAA61212.1 xref: EMBL:AAB39322.1 xref: EMBL:AAC12971.1 xref: EMBL:AAD28535.1 xref: EMBL:AAD28628.1 xref: EMBL:AAF36354.1 xref: EMBL:AAF36355.1 xref: EMBL:AAF36356.1 xref: EMBL:AAF36357.1 xref: EMBL:AAF36358.1 xref: EMBL:AAF36359.1 xref: EMBL:AAF36360.1 xref: EMBL:AAF36361.1 xref: EMBL:AAF36362.1 xref: EMBL:AAF36374.1 xref: EMBL:AAF36375.1 xref: EMBL:AAF36376.1 xref: EMBL:AAF36377.1 xref: EMBL:AAF36378.1 xref: EMBL:AAF36379.1 xref: EMBL:AAF36380.1 xref: EMBL:AAF36381.1 xref: EMBL:AAF36382.1 xref: EMBL:AAF63442.1 xref: EMBL:AAF63443.1 xref: EMBL:AAG28785.1 xref: EMBL:AAH03596.1 xref: EMBL:AAK76358.1 xref: EMBL:AAK76359.1 xref: EMBL:AAP30003.1 xref: EMBL:AAQ90158.1 xref: EMBL:AAR10356.1 xref: EMBL:AAR13239.1 xref: EMBL:AAV80424.1 xref: EMBL:BAC16799.1 xref: EMBL:CAA25652.1 xref: EMBL:CAA26306.1 xref: EMBL:CAA38095.1 xref: EMBL:CAA42626.1 xref: EMBL:CAA42627.1 xref: EMBL:CAA42628.1 xref: EMBL:CAA42629.1 xref: EMBL:CAA42630.1 xref: EMBL:CAA42631.1 xref: EMBL:CAA42632.1 xref: EMBL:CAA42633.1 xref: EMBL:CAA42634.1 xref: EMBL:CAA42635.1 xref: UniProtKB:P04637 xref: UniProtKB:Q15086 xref: UniProtKB:Q15087 xref: UniProtKB:Q15088 xref: UniProtKB:Q16535 xref: UniProtKB:Q16807 xref: UniProtKB:Q16808 xref: UniProtKB:Q16809 xref: UniProtKB:Q16810 xref: UniProtKB:Q16811 xref: UniProtKB:Q16848 xref: UniProtKB:Q86UG1 xref: UniProtKB:Q8J016 xref: UniProtKB:Q99659 xref: UniProtKB:Q9BTM4 xref: UniProtKB:Q9HAQ8 xref: UniProtKB:Q9NP68 xref: UniProtKB:Q9NPJ2 xref: UniProtKB:Q9NZD0 xref: UniProtKB:Q9UBI2 xref: UniProtKB:Q9UQ61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005245 ! TP53_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005741 ! mageb18-tp53 physical interaction relationship: participates_in CCO:I0005862 ! dvl2-tp53 physical interaction relationship: participates_in CCO:I0005976 ! nedd8-tp53-1 neddylation relationship: participates_in CCO:I0005978 ! e6-e6ap-tp53 physical interaction relationship: participates_in CCO:I0005979 ! e6ap-tp53 physical interaction relationship: participates_in CCO:I0006029 ! npm1-tp53-2 physical interaction relationship: participates_in CCO:I0006033 ! wrn-p53-3 colocalization relationship: participates_in CCO:I0006070 ! tp53-nfya-8 colocalization relationship: participates_in CCO:I0006221 ! mdm2-daxx physical interaction relationship: participates_in CCO:I0006222 ! ubp7-daxx physical interaction relationship: participates_in CCO:I0006246 ! tp53-fbxo11-3 physical interaction relationship: participates_in CCO:I0006319 ! npm1-tp53-3 physical interaction relationship: participates_in CCO:I0006320 ! npm1-tp53-4 physical interaction relationship: participates_in CCO:I0006344 ! tp53-lap-2 colocalization relationship: participates_in CCO:I0006528 ! mdm2-npm1-6 physical interaction relationship: participates_in CCO:I0006529 ! pias1-p53-1 direct interaction relationship: participates_in CCO:I0006530 ! pias1-p53-2 direct interaction relationship: participates_in CCO:I0006531 ! pias1-p53-3 direct interaction relationship: participates_in CCO:I0006535 ! wrn-p53-1 direct interaction relationship: participates_in CCO:I0006536 ! wrn-p53-2 direct interaction relationship: participates_in CCO:I0006554 ! tp53-lip physical interaction relationship: participates_in CCO:I0006555 ! tp53-cebpb physical interaction relationship: participates_in CCO:I0006562 ! tp53-nfya-2 physical interaction relationship: participates_in CCO:I0006564 ! tp53-nfya-3 physical interaction relationship: participates_in CCO:I0006565 ! tp53-nfya-4 physical interaction relationship: participates_in CCO:I0006567 ! tp53-nfya-7 physical interaction relationship: participates_in CCO:I0006612 ! p53-sin3a-2 physical interaction relationship: participates_in CCO:I0006655 ! dvl2-tp53-1 physical interaction relationship: participates_in CCO:I0006656 ! mageb18-tp53-1 physical interaction relationship: participates_in CCO:I0006657 ! scamp1-tp53 physical interaction relationship: participates_in CCO:I0006698 ! tp53-tbp1 physical interaction relationship: participates_in CCO:I0006699 ! tp53-tbp-2 physical interaction relationship: participates_in CCO:I0006763 ! usp7-tp53-5 physical interaction relationship: participates_in CCO:I0006780 ! tp53-fbxo11-2 direct interaction relationship: participates_in CCO:I0006795 ! tp53-hdac1 physical interaction relationship: participates_in CCO:I0006806 ! tp53-pias4-3 physical interaction relationship: participates_in CCO:I0006857 ! p53-crebbp-6 physical interaction relationship: participates_in CCO:I0006873 ! tp53-hipk1-2 physical interaction relationship: participates_in CCO:I0006900 ! atr-tp53-1 phosphorylation relationship: participates_in CCO:I0006917 ! nfya-tp53 physical interaction relationship: participates_in CCO:I0006918 ! nfya-tp53-1 physical interaction relationship: participates_in CCO:I0006919 ! tp53-nfya-5 physical interaction relationship: participates_in CCO:I0006920 ! tp53-nfya-6 physical interaction relationship: participates_in CCO:I0006921 ! nfya-tp53-2 physical interaction relationship: participates_in CCO:I0006926 ! p53-mdm2-2 physical interaction relationship: participates_in CCO:I0006970 ! huew1-tp53-1 physical interaction relationship: participates_in CCO:I0006971 ! tp53-huew1-2 physical interaction relationship: participates_in CCO:I0006980 ! gnl3-p53 physical interaction relationship: participates_in CCO:I0006990 ! p53-pml-1 physical interaction relationship: participates_in CCO:I0007027 ! tp53-pias4-2 physical interaction relationship: participates_in CCO:I0007083 ! p53-crebbp-2 physical interaction relationship: participates_in CCO:I0007084 ! p53-crebbp-3 physical interaction relationship: participates_in CCO:I0007085 ! p53-crebbp-4 physical interaction relationship: participates_in CCO:I0007086 ! p53-crebbp-5 physical interaction relationship: participates_in CCO:I0007099 ! mdm2-p53-1 direct interaction relationship: participates_in CCO:I0007166 ! tp53-tp53bp1-1 direct interaction relationship: participates_in CCO:I0007233 ! rad51-tp53-1 physical interaction relationship: participates_in CCO:I0007234 ! rad51-tp53-2 physical interaction relationship: participates_in CCO:I0007241 ! hd-p53-2 physical interaction relationship: participates_in CCO:I0007242 ! p53-crebbp-1 physical interaction relationship: participates_in CCO:I0007243 ! p53-sin3a-1 physical interaction relationship: participates_in CCO:I0007322 ! mapkapk5-tp53 phosphorylation relationship: participates_in CCO:I0007324 ! mapkapk5-tp53-1 phosphorylation relationship: participates_in CCO:I0007325 ! mapk11-tp53-1 phosphorylation relationship: participates_in CCO:I0007352 ! cables1-tp53-3 physical interaction relationship: participates_in CCO:I0007361 ! p53-p300-1 physical interaction relationship: participates_in CCO:I0007362 ! p53-jmy-1 physical interaction relationship: participates_in CCO:I0007380 ! phb-tp53-2 colocalization relationship: participates_in CCO:I0007381 ! ubp7-daxx-6 physical interaction relationship: participates_in CCO:I0007384 ! usp7-tp53 physical interaction relationship: participates_in CCO:I0007385 ! usp7-tp53-1 physical interaction relationship: participates_in CCO:I0007386 ! usp7-tp53-2 physical interaction relationship: participates_in CCO:I0007434 ! tp53-hipk1-1 physical interaction relationship: participates_in CCO:I0007449 ! bmx-tp53-1 physical interaction relationship: participates_in CCO:I0007451 ! tp53-lap-1 physical interaction relationship: participates_in CCO:I0007461 ! usp7-tp53-3 direct interaction relationship: participates_in CCO:I0007467 ! tp53-tp53bp2-1 direct interaction relationship: participates_in CCO:I0007491 ! phb-tp53-4 colocalization relationship: participates_in CCO:I0007568 ! tp53-huew1-1 physical interaction relationship: participates_in CCO:I0007577 ! tp53-btbd2-1 physical interaction relationship: participates_in CCO:I0007578 ! p53-wrn-1 direct interaction relationship: participates_in CCO:I0007579 ! p53-wrn-2 direct interaction relationship: participates_in CCO:I0007581 ! p53-rpa1-8 physical interaction relationship: participates_in CCO:I0007707 ! tp53-nfya physical interaction relationship: participates_in CCO:I0007737 ! hd-p53-3 physical interaction relationship: participates_in CCO:I0007738 ! hd-p53-4 physical interaction relationship: participates_in CCO:I0007802 ! phb-tp53-1 colocalization relationship: participates_in CCO:I0007808 ! ubp7-daxx-7 physical interaction relationship: participates_in CCO:I0007809 ! ubp7-daxx-8 physical interaction relationship: participates_in CCO:I0007810 ! ubp7-daxx-9 physical interaction relationship: participates_in CCO:I0007811 ! mdm2-daxx-2 physical interaction relationship: participates_in CCO:I0007824 ! tp53-nfya-1 physical interaction relationship: participates_in CCO:I0007835 ! tp53-fbxo11-1 physical interaction relationship: participates_in CCO:I0007849 ! hd-p53-1 physical interaction relationship: participates_in CCO:I0007924 ! phb-tp53 colocalization relationship: participates_in CCO:I0007931 ! usp7-tp53-4 physical interaction relationship: participates_in CCO:I0007949 ! tp53-hmgb1 physical interaction relationship: participates_in CCO:I0007982 ! cdkn2c-tp53 physical interaction relationship: participates_in CCO:I0007987 ! erh-tp53 physical interaction relationship: participates_in CCO:I0007993 ! znf24-tp53 physical interaction relationship: participates_in CCO:I0007995 ! arih2-tp53 physical interaction relationship: participates_in CCO:I0007999 ! btbd2-tp53 physical interaction relationship: participates_in CCO:I0008000 ! ccl18-tp53 physical interaction relationship: participates_in CCO:I0008003 ! cdc42-tp53 physical interaction relationship: participates_in CCO:I0008010 ! eif2s2-tp53 physical interaction relationship: participates_in CCO:I0008018 ! lama4-tp53 physical interaction relationship: participates_in CCO:I0008021 ! mad2l1bp-tp53 physical interaction relationship: participates_in CCO:I0008023 ! mphosph6-tp53 physical interaction relationship: participates_in CCO:I0008029 ! pafah1b3-tp53 physical interaction relationship: participates_in CCO:I0008030 ! pcdha4-tp53 physical interaction relationship: participates_in CCO:I0008033 ! pp-tp53 physical interaction relationship: participates_in CCO:I0008037 ! psmd11-tp53 physical interaction relationship: participates_in CCO:I0008048 ! sat-tp53 physical interaction relationship: participates_in CCO:I0008051 ! serpinb9-tp53 physical interaction relationship: participates_in CCO:I0008052 ! sma3-tp53 physical interaction relationship: participates_in CCO:I0008054 ! snrpn-tp53 physical interaction relationship: participates_in CCO:I0008055 ! sult1e1-tp53 physical interaction relationship: participates_in CCO:I0008059 ! tk1-tp53 physical interaction relationship: participates_in CCO:I0008060 ! tmsb4x-tp53 physical interaction relationship: participates_in CCO:I0008065 ! anxa3-tp53 physical interaction relationship: participates_in CCO:I0008068 ! arl3-tp53 physical interaction relationship: participates_in CCO:I0008069 ! atf3-tp53 physical interaction relationship: participates_in CCO:I0008072 ! bcr-tp53 physical interaction relationship: participates_in CCO:I0008076 ! cct5-tp53 physical interaction relationship: participates_in CCO:I0008089 ! cox17-tp53 physical interaction relationship: participates_in CCO:I0008097 ! dleu1-tp53 physical interaction relationship: participates_in CCO:I0008108 ! fxyd6-tp53 physical interaction relationship: participates_in CCO:I0008114 ! gstm4-tp53 physical interaction relationship: participates_in CCO:I0008124 ! hspb1-tp53 physical interaction relationship: participates_in CCO:I0008138 ! np-tp53 physical interaction relationship: participates_in CCO:I0008168 ! stx5a-tp53 physical interaction relationship: participates_in CCO:I0008187 ! wdr33-tp53 physical interaction relationship: participates_in CCO:I0008265 ! c16orf24-tp53 physical interaction relationship: participates_in CCO:I0008319 ! s100a8-tp53 physical interaction relationship: participates_in CCO:I0008351 ! zcchc10-tp53 physical interaction relationship: participates_in CCO:I0008401 ! kiaa0087-tp53 physical interaction relationship: participates_in CCO:I0008424 ! rab4a-tp53 physical interaction relationship: participates_in CCO:I0008440 ! thap8-tp53 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000684 ! ER overload response relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: participates_in CCO:P0000842 ! caspase activation via cytochrome c relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0013340 ! P53_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0013341 ! P53_HUMAN-Phosphothreonine18 relationship: transforms_into CCO:B0013342 ! P53_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0013343 ! P53_HUMAN-Phosphothreonine55 relationship: transforms_into CCO:B0013344 ! P53_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0013345 ! P53_HUMAN-N6-acetyllysine305 relationship: transforms_into CCO:B0013346 ! P53_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0013347 ! P53_HUMAN-N6-acetyllysine373 relationship: transforms_into CCO:B0013348 ! P53_HUMAN-N6-acetyllysine382 relationship: transforms_into CCO:B0013349 ! P53_HUMAN-O-(5'-phospho-RNA)-serine392 relationship: transforms_into CCO:B0013350 ! P53_HUMAN-Phosphoserine392 relationship: transforms_into CCO:B0032856 ! P53_HUMAN-N6-methyllysine370 relationship: transforms_into CCO:B0032857 ! P53_HUMAN-N6-methyllysine372 relationship: transforms_into CCO:B0041169 ! P53_HUMAN-Phosphoserine9 [Term] id: CCO:B0001484 name: IFNW1_HUMAN def: "Interferon omega-1 precursor" [UniProtKB:P05000] synonym: "Interferon alpha-II-1" EXACT [UniProtKB:P05000] xref: EMBL:AAA52724.1 xref: EMBL:AAA70091.1 xref: EMBL:AAH69095.1 xref: EMBL:AAI17291.1 xref: EMBL:AAI17293.1 xref: EMBL:AAV49320.1 xref: EMBL:CAA01011.1 xref: EMBL:CAA26501.1 xref: EMBL:CAA41626.1 xref: EMBL:CAH70158.1 xref: EMBL:EAW58624.1 xref: UniProtKB:P05000 xref: UniProtKB:Q13168 xref: UniProtKB:Q5U802 xref: UniProtKB:Q5VWD0 xref: UniProtKB:Q7M4P5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004866 ! IFNW1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001485 name: INHA_HUMAN def: "Inhibin alpha chain precursor" [UniProtKB:P05111] xref: EMBL:AAA59166.1 xref: EMBL:AAA59167.1 xref: EMBL:AAH06391.1 xref: EMBL:AAP35600.1 xref: EMBL:CAA28040.1 xref: UniProtKB:P05111 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004896 ! INHA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0003570 ! activin inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001778 ! inhibin A complex relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000346 ! regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation relationship: participates_in CCO:P0002269 ! negative regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002392 ! negative regulation of B cell differentiation relationship: participates_in CCO:P0002464 ! negative regulation of macrophage differentiation relationship: participates_in CCO:P0002742 ! positive regulation of follicle-stimulating hormone secretion relationship: participates_in CCO:P0002743 ! negative regulation of follicle-stimulating hormone secretion [Term] id: CCO:B0001486 name: FGF1_HUMAN def: "Heparin-binding growth factor 1 precursor" [UniProtKB:P05230] synonym: "Acidic fibroblast growth factor" EXACT [UniProtKB:P05230] synonym: "aFGF" EXACT [UniProtKB:P05230] synonym: "Beta-endothelial cell growth factor" EXACT [UniProtKB:P05230] synonym: "ECGF-beta" EXACT [UniProtKB:P05230] synonym: "HBGF-1" EXACT [UniProtKB:P05230] xref: EMBL:AAA51672.1 xref: EMBL:AAA51673.1 xref: EMBL:AAA52446.1 xref: EMBL:AAA52638.1 xref: EMBL:AAA79245.1 xref: EMBL:AAB29057.2 xref: EMBL:AAH32697.1 xref: EMBL:AAS99352.1 xref: EMBL:CAA36206.1 xref: EMBL:CAA46661.1 xref: UniProtKB:P05230 xref: UniProtKB:P07502 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004632 ! FGF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006067 ! fgf1-fgfr2-1 direct interaction relationship: participates_in CCO:I0007432 ! fgf-fgfr-2 direct interaction relationship: participates_in CCO:I0007433 ! fgf-fgfr-3 direct interaction relationship: participates_in CCO:I0007435 ! fgf-fgfr-1 direct interaction relationship: participates_in CCO:I0007469 ! fgf1-fgfr2-2 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: transforms_into CCO:B0011876 ! FGF1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0001487 name: JUN_HUMAN def: "Transcription factor AP-1" [UniProtKB:P05412] synonym: "Activator protein 1" EXACT [UniProtKB:P05412] synonym: "AP1" EXACT [UniProtKB:P05412] synonym: "p39" EXACT [UniProtKB:P05412] synonym: "Proto-oncogene c-jun" EXACT [UniProtKB:P05412] synonym: "V-jun avian sarcoma virus 17 oncogene homolog" EXACT [UniProtKB:P05412] xref: EMBL:AAA59197.1 xref: EMBL:AAH06175.1 xref: EMBL:AAH09874.2 xref: EMBL:AAH68522.1 xref: EMBL:AAO22993.1 xref: EMBL:AAV38564.1 xref: EMBL:CAC10201.1 xref: UniProtKB:P05412 xref: UniProtKB:Q96G93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004913 ! JUN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006719 ! mapk8-jun-1 phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000887 ! cellular process relationship: participates_in CCO:P0001513 ! negative regulation of protein amino acid autophosphorylation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0012449 ! JUN_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0012450 ! JUN_HUMAN-Phosphoserine73 [Term] id: CCO:B0001489 name: K1C18_HUMAN def: "Keratin, type I cytoskeletal 18" [UniProtKB:P05783] synonym: "Cell proliferation-inducing gene 46 protein" EXACT [UniProtKB:P05783] synonym: "CK-18" EXACT [UniProtKB:P05783] synonym: "Cytokeratin-18" EXACT [UniProtKB:P05783] synonym: "K18" EXACT [UniProtKB:P05783] synonym: "Keratin-18" EXACT [UniProtKB:P05783] xref: EMBL:AAA59461.1 xref: EMBL:AAH00180.1 xref: EMBL:AAH00698.1 xref: EMBL:AAH04253.1 xref: EMBL:AAH08636.1 xref: EMBL:AAH20982.1 xref: EMBL:AAH72017.1 xref: EMBL:AAV38219.1 xref: EMBL:AAX07828.1 xref: EMBL:BAD96813.1 xref: EMBL:CAA31369.1 xref: EMBL:CAA31375.1 xref: EMBL:CAA31377.1 xref: UniProtKB:P05783 xref: UniProtKB:Q53G38 xref: UniProtKB:Q5U0N8 xref: UniProtKB:Q9BW26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004923 ! KRT18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005746 ! krt18-q9bvr6 physical interaction relationship: participates_in CCO:I0005766 ! krt15-krt18 physical interaction relationship: participates_in CCO:I0005838 ! krt18-ldoc1 physical interaction relationship: participates_in CCO:I0005839 ! exoc8-krt18 physical interaction relationship: participates_in CCO:I0005902 ! hgs-krt18 physical interaction relationship: participates_in CCO:I0005903 ! krt18-nme7 physical interaction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007196 ! krt18-shc1-1 colocalization relationship: participates_in CCO:I0007341 ! krt8-krt18 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0012460 ! K1C18_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0012461 ! K1C18_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0012462 ! K1C18_HUMAN-Phosphothreonine8 relationship: transforms_into CCO:B0012463 ! K1C18_HUMAN-Phosphothreonine11 relationship: transforms_into CCO:B0012464 ! K1C18_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0012465 ! K1C18_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0012466 ! K1C18_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0012467 ! K1C18_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0012468 ! K1C18_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0012469 ! K1C18_HUMAN-Phosphotyrosine36 relationship: transforms_into CCO:B0012470 ! K1C18_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0012471 ! K1C18_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0012472 ! K1C18_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0012473 ! K1C18_HUMAN-Phosphoserine401 relationship: transforms_into CCO:B0012474 ! K1C18_HUMAN-Phosphothreonine404 relationship: transforms_into CCO:B0067241 ! K1C18_HUMAN-Phosphotyrosine13 [Term] id: CCO:B0001490 name: LCK_HUMAN def: "Proto-oncogene tyrosine-protein kinase LCK" [UniProtKB:P06239] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P06239] synonym: "LSK" EXACT [UniProtKB:P06239] synonym: "Lymphocyte cell-specific protein-tyrosine kinase" EXACT [UniProtKB:P06239] synonym: "p56-LCK" EXACT [UniProtKB:P06239] synonym: "T cell-specific protein-tyrosine kinase" EXACT [UniProtKB:P06239] xref: EMBL:AAA18225.1 xref: EMBL:AAA59501.1 xref: EMBL:AAA59502.1 xref: EMBL:AAA59503.1 xref: EMBL:AAC50287.1 xref: EMBL:AAF34794.1 xref: EMBL:AAH13200.1 xref: EMBL:CAA28165.1 xref: EMBL:CAA28691.1 xref: EMBL:CAA29667.1 xref: EMBL:CAA31884.1 xref: EMBL:CAA32211.1 xref: EMBL:CAI22320.1 xref: EMBL:CAI22321.1 xref: UniProtKB:P06239 xref: UniProtKB:P07100 xref: UniProtKB:Q12850 xref: UniProtKB:Q13152 xref: UniProtKB:Q5TDH8 xref: UniProtKB:Q5TDH9 xref: UniProtKB:Q96DW4 xref: UniProtKB:Q9NYT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004974 ! LCK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000251 ! glycoprotein binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0005692 ! CD4 receptor binding relationship: has_function CCO:F0005693 ! CD8 receptor binding relationship: has_function CCO:F0005873 ! phosphoinositide 3-kinase binding relationship: has_function CCO:F0008060 ! ATPase binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000043 ! pericentriolar material relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:I0006265 ! lck-med28-2 physical interaction relationship: participates_in CCO:I0006283 ! lck-lad-3 physical interaction relationship: participates_in CCO:I0006623 ! khdrbs1-lck-1 physical interaction relationship: participates_in CCO:I0006790 ! lck-med28-3 phosphorylation relationship: participates_in CCO:I0006828 ! lck-med28-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007195 ! lck-ptprc physical interaction relationship: participates_in CCO:I0007480 ! fyn-med28-4 physical interaction relationship: participates_in CCO:I0007519 ! lck-khdrbs1 physical interaction relationship: participates_in CCO:I0007605 ! wasl-lck-1 phosphorylation relationship: participates_in CCO:I0007606 ! wasl-lck-2 phosphorylation relationship: participates_in CCO:I0007965 ! lck-sam68-1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0002980 ! positive regulation of T cell receptor signaling pathway relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation relationship: participates_in CCO:P0003065 ! regulation of lymphocyte activation relationship: transforms_into CCO:B0012690 ! LCK_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0012691 ! LCK_HUMAN-Phosphotyrosine192 relationship: transforms_into CCO:B0012692 ! LCK_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0012693 ! LCK_HUMAN-Phosphotyrosine394 relationship: transforms_into CCO:B0012694 ! LCK_HUMAN-Phosphothreonine501 relationship: transforms_into CCO:B0012695 ! LCK_HUMAN-Phosphotyrosine505 [Term] id: CCO:B0001491 name: RB_HUMAN def: "Retinoblastoma-associated protein" [UniProtKB:P06400] synonym: "p105-Rb" EXACT [UniProtKB:P06400] synonym: "pp110" EXACT [UniProtKB:P06400] synonym: "pRb" EXACT [UniProtKB:P06400] synonym: "Rb" EXACT [UniProtKB:P06400] xref: EMBL:AAA53483.1 xref: EMBL:AAA53484.1 xref: EMBL:AAA65735.1 xref: EMBL:AAA65736.1 xref: EMBL:AAA65737.1 xref: EMBL:AAA65738.1 xref: EMBL:AAA65739.1 xref: EMBL:AAA65740.1 xref: EMBL:AAA65741.1 xref: EMBL:AAA69806.1 xref: EMBL:AAA69807.1 xref: EMBL:AAA69808.1 xref: EMBL:AAB59465.1 xref: EMBL:AAB59467.1 xref: EMBL:AAB59471.1 xref: EMBL:AAB59473.1 xref: EMBL:AAB59482.1 xref: EMBL:AAH39060.1 xref: EMBL:AAH40540.1 xref: EMBL:AAN64133.1 xref: EMBL:CAA34462.1 xref: EMBL:CAH70901.1 xref: EMBL:CAH72243.1 xref: UniProtKB:P06400 xref: UniProtKB:P78499 xref: UniProtKB:Q5VW46 xref: UniProtKB:Q8IZL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005454 ! RB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006052 ! pa2g4-rb1-1 physical interaction relationship: participates_in CCO:I0006053 ! rb1-pa2g4-2 physical interaction relationship: participates_in CCO:I0006054 ! pa2g4-rb1-2 physical interaction relationship: participates_in CCO:I0006196 ! rb1-taf1-1 physical interaction relationship: participates_in CCO:I0006457 ! ahr-rb1 physical interaction relationship: participates_in CCO:I0006458 ! ahr-rb1-1 physical interaction relationship: participates_in CCO:I0006561 ! morf4l2-rb1-1 physical interaction relationship: participates_in CCO:I0007003 ! e2f3-rb physical interaction relationship: participates_in CCO:I0007008 ! e2f3-rb-1 physical interaction relationship: participates_in CCO:I0007009 ! e2f3-rb-2 physical interaction relationship: participates_in CCO:I0007309 ! rb1-hdac1 physical interaction relationship: participates_in CCO:I0007350 ! cdk2-rb1-1 phosphorylation relationship: participates_in CCO:I0007351 ! cdk2-rb1-2 phosphorylation relationship: participates_in CCO:I0007418 ! rb1-pa2g4-1 physical interaction relationship: participates_in CCO:I0007496 ! rb1-e2f1 physical interaction relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000039 ! M phase relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000313 ! G1 phase relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002465 ! positive regulation of macrophage differentiation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013799 ! RB_HUMAN-Phosphoserine249 relationship: transforms_into CCO:B0013800 ! RB_HUMAN-Phosphothreonine252 relationship: transforms_into CCO:B0013801 ! RB_HUMAN-Phosphothreonine373 relationship: transforms_into CCO:B0013802 ! RB_HUMAN-Phosphoserine807 relationship: transforms_into CCO:B0013803 ! RB_HUMAN-Phosphoserine811 relationship: transforms_into CCO:B0013804 ! RB_HUMAN-Phosphothreonine826 relationship: transforms_into CCO:B0048372 ! RB_HUMAN-Phosphothreonine356 [Term] id: CCO:B0001493 name: CDC2_HUMAN def: "Cell division control protein 2 homolog" [UniProtKB:P06493] synonym: "CDK1" EXACT [UniProtKB:P06493] synonym: "Cyclin-dependent kinase 1" EXACT [UniProtKB:P06493] synonym: "EC 2.7.11.22" EXACT [UniProtKB:P06493] synonym: "EC 2.7.11.23" EXACT [UniProtKB:P06493] synonym: "p34 protein kinase" EXACT [UniProtKB:P06493] xref: EMBL:AAH14563.1 xref: EMBL:AAM34793.1 xref: EMBL:AAP35650.1 xref: EMBL:BAA26001.1 xref: EMBL:CAA28963.1 xref: EMBL:CAA68376.1 xref: UniProtKB:O60764 xref: UniProtKB:P06493 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004288 ! CDC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006614 ! cdc2-myt1-1 phosphorylation relationship: participates_in CCO:I0006849 ! lats1-cdc2-1 physical interaction relationship: participates_in CCO:I0006861 ! cdc2-ccnb1-1 physical interaction relationship: participates_in CCO:I0006959 ! pkmyt1-cdc2-1 phosphorylation relationship: participates_in CCO:I0007087 ! pkmyt1-cdc2-2 phosphorylation relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007533 ! cdt1-cdk2-1 physical interaction relationship: participates_in CCO:I0007729 ! lats1-cdc2-2 physical interaction relationship: participates_in CCO:I0007895 ! cyclina1_cdk1_human direct interaction relationship: participates_in CCO:I0007896 ! cyclina2_cdk1_human direct interaction relationship: participates_in CCO:I0007899 ! cyclinb1_cdk1_human direct interaction relationship: participates_in CCO:I0007900 ! cyclinb2_cdk1_human direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011078 ! CDC2_HUMAN-Phosphothreonine14 relationship: transforms_into CCO:B0011079 ! CDC2_HUMAN-Phosphotyrosine15 relationship: transforms_into CCO:B0011080 ! CDC2_HUMAN-Phosphotyrosine19 relationship: transforms_into CCO:B0011081 ! CDC2_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0048184 ! CDC2_HUMAN-Phosphotyrosine160 [Term] id: CCO:B0001494 name: S10A6_HUMAN def: "Protein S100-A6" [UniProtKB:P06703] synonym: "Calcyclin" EXACT [UniProtKB:P06703] synonym: "Growth factor-inducible protein 2A9" EXACT [UniProtKB:P06703] synonym: "MLN 4" EXACT [UniProtKB:P06703] synonym: "PRA" EXACT [UniProtKB:P06703] synonym: "Prolactin receptor-associated protein" EXACT [UniProtKB:P06703] synonym: "S100 calcium-binding protein A6" EXACT [UniProtKB:P06703] xref: EMBL:AAA35886.1 xref: EMBL:AAA51905.1 xref: EMBL:AAA51906.1 xref: EMBL:AAH01431.1 xref: EMBL:AAH09017.1 xref: EMBL:AAK59702.1 xref: EMBL:AAP35611.1 xref: EMBL:CAI14752.1 xref: UniProtKB:P06703 xref: UniProtKB:Q5RHS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005552 ! S100A6_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0007315 ! S100 beta binding relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006057 ! s100b-s100a6-1 physical interaction relationship: participates_in CCO:I0006219 ! s100b-s100a6-3 physical interaction relationship: participates_in CCO:I0006894 ! s100a6-s100a6-1 physical interaction relationship: participates_in CCO:I0006895 ! s100a6-s100b-1 physical interaction relationship: participates_in CCO:I0006896 ! s100b-s100a6-2 physical interaction relationship: participates_in CCO:I0007148 ! s100b-s100a11-s100a6 colocalization relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation [Term] id: CCO:B0001495 name: NPM_HUMAN def: "Nucleophosmin" [UniProtKB:P06748] synonym: "NPM" EXACT [UniProtKB:P06748] synonym: "Nucleolar phosphoprotein B23" EXACT [UniProtKB:P06748] synonym: "Nucleolar protein NO38" EXACT [UniProtKB:P06748] synonym: "Numatrin" EXACT [UniProtKB:P06748] xref: EMBL:AAA36380.1 xref: EMBL:AAA36385.1 xref: EMBL:AAA36473.1 xref: EMBL:AAA36474.1 xref: EMBL:AAA58386.1 xref: EMBL:AAA58698.1 xref: EMBL:AAB00112.1 xref: EMBL:AAB00113.1 xref: EMBL:AAB94739.1 xref: EMBL:AAH02398.1 xref: EMBL:AAH08495.1 xref: EMBL:AAH09623.1 xref: EMBL:AAH12566.1 xref: EMBL:AAH14349.1 xref: EMBL:AAH16716.1 xref: EMBL:AAH16768.1 xref: EMBL:AAH16824.1 xref: EMBL:AAH21668.1 xref: EMBL:AAH21983.1 xref: EMBL:AAH50628.1 xref: EMBL:AAP35657.1 xref: EMBL:AAQ24860.1 xref: EMBL:AAW67752.1 xref: EMBL:AAW67753.1 xref: EMBL:AAW67754.1 xref: EMBL:AAW67755.1 xref: EMBL:AAW67756.1 xref: EMBL:AAW67757.1 xref: EMBL:AAW67758.1 xref: EMBL:ABC40399.1 xref: EMBL:BAA08343.1 xref: EMBL:CAA34809.1 xref: UniProtKB:P06748 xref: UniProtKB:P08693 xref: UniProtKB:Q12826 xref: UniProtKB:Q13440 xref: UniProtKB:Q13441 xref: UniProtKB:Q14115 xref: UniProtKB:Q5EU94 xref: UniProtKB:Q5EU95 xref: UniProtKB:Q5EU96 xref: UniProtKB:Q5EU97 xref: UniProtKB:Q5EU98 xref: UniProtKB:Q5EU99 xref: UniProtKB:Q6V962 xref: UniProtKB:Q8WTW5 xref: UniProtKB:Q96AT6 xref: UniProtKB:Q96DC4 xref: UniProtKB:Q96EA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005212 ! NPM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006029 ! npm1-tp53-2 physical interaction relationship: participates_in CCO:I0006318 ! mdm2-npm1-4 physical interaction relationship: participates_in CCO:I0006319 ! npm1-tp53-3 physical interaction relationship: participates_in CCO:I0006320 ! npm1-tp53-4 physical interaction relationship: participates_in CCO:I0006345 ! pa2g4-npm-1 colocalization relationship: participates_in CCO:I0006346 ! pa2g4-npm-2 colocalization relationship: participates_in CCO:I0006392 ! map3k14-rara physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006527 ! mdm2-npm1-2 physical interaction relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0006673 ! hrmt1l1-rara-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007326 ! ncoa6-rara-1 physical interaction relationship: participates_in CCO:I0007327 ! ncoa6-rara-2 physical interaction relationship: participates_in CCO:I0007753 ! mdm2-npm1-1 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0007874 ! cdkn2a-huew1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000108 ! centrosome cycle relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0013246 ! NPM_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0013247 ! NPM_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0013248 ! NPM_HUMAN-Phosphoserine70 relationship: transforms_into CCO:B0013249 ! NPM_HUMAN-Phosphothreonine75 relationship: transforms_into CCO:B0013250 ! NPM_HUMAN-Phosphothreonine95 relationship: transforms_into CCO:B0013251 ! NPM_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0013252 ! NPM_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0013253 ! NPM_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0013254 ! NPM_HUMAN-N6-acetyllysine150 relationship: transforms_into CCO:B0013255 ! NPM_HUMAN-N6-acetyllysine154 relationship: transforms_into CCO:B0013256 ! NPM_HUMAN-Phosphothreonine199 relationship: transforms_into CCO:B0013257 ! NPM_HUMAN-N6-acetyllysine212 relationship: transforms_into CCO:B0013258 ! NPM_HUMAN-Phosphothreonine234 relationship: transforms_into CCO:B0013259 ! NPM_HUMAN-Phosphothreonine237 relationship: transforms_into CCO:B0013260 ! NPM_HUMAN-Phosphoserine254 relationship: transforms_into CCO:B0013261 ! NPM_HUMAN-Phosphoserine260 relationship: transforms_into CCO:B0048339 ! NPM_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0048340 ! NPM_HUMAN-Phosphothreonine279 [Term] id: CCO:B0001496 name: FUMH_HUMAN def: "Fumarate hydratase, mitochondrial precursor" [UniProtKB:P07954] synonym: "EC 4.2.1.2" EXACT [UniProtKB:P07954] synonym: "Fumarase" EXACT [UniProtKB:P07954] xref: EMBL:AAA52483.1 xref: EMBL:AAB66354.1 xref: EMBL:AAD00071.1 xref: EMBL:AAH03108.1 xref: EMBL:AAH17444.1 xref: EMBL:AAP88841.1 xref: UniProtKB:P07954 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004663 ! FH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0011900 ! FUMH_HUMAN-N6-acetyllysine66 relationship: transforms_into CCO:B0011901 ! FUMH_HUMAN-N6-acetyllysine115 relationship: transforms_into CCO:B0011902 ! FUMH_HUMAN-N6-acetyllysine477 relationship: transforms_into CCO:B0066301 ! FUMH_HUMAN-Phosphotyrosine491 [Term] id: CCO:B0001497 name: IGF1R_HUMAN def: "Insulin-like growth factor 1 receptor precursor" [UniProtKB:P08069] synonym: "CD221 antigen" EXACT [UniProtKB:P08069] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P08069] synonym: "IGF-I receptor" EXACT [UniProtKB:P08069] synonym: "Insulin-like growth factor I receptor" EXACT [UniProtKB:P08069] xref: EMBL:AAB59399.1 xref: EMBL:AAI13611.1 xref: EMBL:AAI13613.1 xref: EMBL:AAP81165.1 xref: EMBL:CAA28030.1 xref: UniProtKB:P08069 xref: UniProtKB:Q14CV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004867 ! IGF1R_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006285 ! igf1r-shc1-1 physical interaction relationship: participates_in CCO:I0006289 ! igf1r-ywhab-1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001084 ! phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002755 ! insulin-like growth factor receptor signaling pathway relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0012336 ! IGF1R_HUMAN-Phosphotyrosine980 relationship: transforms_into CCO:B0012337 ! IGF1R_HUMAN-Phosphotyrosine1161 relationship: transforms_into CCO:B0012338 ! IGF1R_HUMAN-Phosphotyrosine1165 relationship: transforms_into CCO:B0012339 ! IGF1R_HUMAN-Phosphotyrosine1166 [Term] id: CCO:B0001498 name: INHBA_HUMAN def: "Inhibin beta A chain precursor" [UniProtKB:P08476] synonym: "Activin beta-A chain" EXACT [UniProtKB:P08476] synonym: "EDF" EXACT [UniProtKB:P08476] synonym: "Erythroid differentiation protein" EXACT [UniProtKB:P08476] xref: EMBL:AAA35787.1 xref: EMBL:AAA59168.1 xref: EMBL:AAH07858.1 xref: EMBL:AAQ96861.1 xref: EMBL:CAA28041.1 xref: EMBL:CAA40805.1 xref: EMBL:CAA40806.1 xref: EMBL:CAA51163.1 xref: UniProtKB:P08476 xref: UniProtKB:Q14599 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004897 ! INHBA_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0003570 ! activin inhibitor activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0007318 ! follistatin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001775 ! activin A complex relationship: located_in CCO:C0001778 ! inhibin A complex relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001715 ! regulation of activin receptor signaling pathway relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation relationship: participates_in CCO:P0002269 ! negative regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002392 ! negative regulation of B cell differentiation relationship: participates_in CCO:P0002462 ! positive regulation of erythrocyte differentiation relationship: participates_in CCO:P0002464 ! negative regulation of macrophage differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002742 ! positive regulation of follicle-stimulating hormone secretion relationship: participates_in CCO:P0002743 ! negative regulation of follicle-stimulating hormone secretion [Term] id: CCO:B0001499 name: CD45_HUMAN def: "Leukocyte common antigen precursor" [UniProtKB:P08575] synonym: "CD45 antigen" EXACT [UniProtKB:P08575] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P08575] synonym: "L-CA" EXACT [UniProtKB:P08575] synonym: "T200" EXACT [UniProtKB:P08575] xref: EMBL:AAD15273.2 xref: EMBL:CAA68269.1 xref: EMBL:CAA68669.1 xref: UniProtKB:P08575 xref: UniProtKB:Q16614 xref: UniProtKB:Q9H0Y6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004277 ! PTPRC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007195 ! lck-ptprc physical interaction relationship: participates_in CCO:P0000215 ! regulation of S phase relationship: participates_in CCO:P0000346 ! regulation of cell cycle relationship: participates_in CCO:P0000489 ! negative regulation of T cell mediated cytotoxicity relationship: participates_in CCO:P0000512 ! negative regulation of cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0002040 ! B cell proliferation relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway relationship: participates_in CCO:P0002975 ! positive regulation of antigen receptor-mediated signaling pathway relationship: transforms_into CCO:B0011049 ! CD45_HUMAN-Phosphoserine995 relationship: transforms_into CCO:B0011050 ! CD45_HUMAN-Phosphoserine1003 relationship: transforms_into CCO:B0011051 ! CD45_HUMAN-Phosphoserine1007 [Term] id: CCO:B0001500 name: FGF4_HUMAN def: "Fibroblast growth factor 4 precursor" [UniProtKB:P08620] synonym: "FGF-4" EXACT [UniProtKB:P08620] synonym: "HBGF-4" EXACT [UniProtKB:P08620] synonym: "Heparin secretory-transforming protein" EXACT [UniProtKB:P08620] synonym: "Heparin-binding growth factor 4" EXACT [UniProtKB:P08620] synonym: "HST" EXACT [UniProtKB:P08620] synonym: "HST-1" EXACT [UniProtKB:P08620] synonym: "Transforming protein KS3" EXACT [UniProtKB:P08620] xref: EMBL:AAA59473.1 xref: EMBL:AAB59555.1 xref: UniProtKB:P08620 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004635 ! FGF4_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0001147 ! stem cell maintenance relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0001501 name: K2C7_HUMAN def: "Keratin, type II cytoskeletal 7" [UniProtKB:P08729] synonym: "CK-7" EXACT [UniProtKB:P08729] synonym: "Cytokeratin-7" EXACT [UniProtKB:P08729] synonym: "K7" EXACT [UniProtKB:P08729] synonym: "Keratin-7" EXACT [UniProtKB:P08729] synonym: "Sarcolectin" EXACT [UniProtKB:P08729] xref: EMBL:AAH02700.1 xref: EMBL:AAN64031.1 xref: EMBL:AAN64035.1 xref: EMBL:CAA26956.2 xref: EMBL:CAA31695.1 xref: EMBL:CAB41416.1 xref: UniProtKB:P08729 xref: UniProtKB:Q92676 xref: UniProtKB:Q9BUD8 xref: UniProtKB:Q9Y3R7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004928 ! KRT7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000320 ! interphase relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0012481 ! K2C7_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0012482 ! K2C7_HUMAN-Omega-N-methylated arginine20 relationship: transforms_into CCO:B0012483 ! K2C7_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0012484 ! K2C7_HUMAN-Phosphoserine254 relationship: transforms_into CCO:B0012485 ! K2C7_HUMAN-Phosphotyrosine375 relationship: transforms_into CCO:B0012486 ! K2C7_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0067246 ! K2C7_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0067247 ! K2C7_HUMAN-Phosphotyrosine205 [Term] id: CCO:B0001502 name: FGF2_HUMAN def: "Heparin-binding growth factor 2 precursor" [UniProtKB:P09038] synonym: "Basic fibroblast growth factor" EXACT [UniProtKB:P09038] synonym: "BFGF" EXACT [UniProtKB:P09038] synonym: "HBGF-2" EXACT [UniProtKB:P09038] xref: EMBL:AAA52448.1 xref: EMBL:AAA52533.1 xref: EMBL:AAA52534.1 xref: EMBL:CAA28027.1 xref: EMBL:CAA28028.1 xref: EMBL:CAA28029.1 xref: UniProtKB:P09038 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004633 ! FGF2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0006233 ! fgf2-fgfr2-1 direct interaction relationship: participates_in CCO:I0006234 ! fgf2-fgfr2-2 direct interaction relationship: participates_in CCO:I0006744 ! fgfbp1-fgf2-3 direct interaction relationship: participates_in CCO:I0007164 ! fgf2-fgfr1-2 direct interaction relationship: participates_in CCO:I0007295 ! fgfbp1-fgf2-1 direct interaction relationship: participates_in CCO:I0007296 ! fgfbp1-fgf2-2 direct interaction relationship: participates_in CCO:I0007497 ! fgf2-fgfr1-1 direct interaction relationship: participates_in CCO:P0000410 ! activation of MAPKK activity relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0001212 ! positive regulation of granule cell precursor proliferation relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation relationship: participates_in CCO:P0002725 ! regulation of retinal cell programmed cell death relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0001503 name: DPOLA_HUMAN def: "DNA polymerase alpha catalytic subunit" [UniProtKB:P09884] synonym: "EC 2.7.7.7" EXACT [UniProtKB:P09884] xref: EMBL:AAA52318.1 xref: EMBL:AAP13534.1 xref: EMBL:CAA29920.1 xref: UniProtKB:P09884 xref: UniProtKB:Q86UQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004509 ! POLA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006337 ! pola-pola2-6 physical interaction relationship: participates_in CCO:I0006338 ! pola-pri1-1 physical interaction relationship: participates_in CCO:I0007308 ! smc1-dpola-1 physical interaction relationship: participates_in CCO:I0007909 ! pol-prim_human physical interaction relationship: participates_in CCO:P0000014 ! S phase of mitotic cell cycle relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000635 ! DNA strand elongation during DNA replication relationship: participates_in CCO:P0000636 ! leading strand elongation relationship: participates_in CCO:P0000637 ! lagging strand elongation relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 [Term] id: CCO:B0001504 name: IL8_HUMAN def: "Interleukin-8 precursor" [UniProtKB:P10145] synonym: "C-X-C motif chemokine 8" EXACT [UniProtKB:P10145] synonym: "Emoctakin" EXACT [UniProtKB:P10145] synonym: "GCP-1" EXACT [UniProtKB:P10145] synonym: "Granulocyte chemotactic protein 1" EXACT [UniProtKB:P10145] synonym: "IL-8" EXACT [UniProtKB:P10145] synonym: "MDNCF" EXACT [UniProtKB:P10145] synonym: "MONAP" EXACT [UniProtKB:P10145] synonym: "Monocyte-derived neutrophil chemotactic factor" EXACT [UniProtKB:P10145] synonym: "Monocyte-derived neutrophil-activating peptide" EXACT [UniProtKB:P10145] synonym: "NAP-1" EXACT [UniProtKB:P10145] synonym: "Neutrophil-activating protein 1" EXACT [UniProtKB:P10145] synonym: "Protein 3-10C" EXACT [UniProtKB:P10145] synonym: "T-cell chemotactic factor" EXACT [UniProtKB:P10145] xref: EMBL:AAA35611.1 xref: EMBL:AAA36323.1 xref: EMBL:AAA59158.1 xref: EMBL:AAH13615.1 xref: EMBL:AAK00048.1 xref: EMBL:AAK60276.1 xref: EMBL:AAP35730.1 xref: EMBL:BAA03245.1 xref: EMBL:BAG34815.1 xref: EMBL:CAA68742.1 xref: EMBL:CAA77745.1 xref: EMBL:CAG46948.1 xref: EMBL:EAX05688.1 xref: UniProtKB:B2R4L8 xref: UniProtKB:P10145 xref: UniProtKB:Q6FGF6 xref: UniProtKB:Q6LAE6 xref: UniProtKB:Q96RG6 xref: UniProtKB:Q9C077 xref: UniProtKB:Q9UCE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004883 ! IL8_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001455 ! interleukin-8 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0001245 ! regulation of cell adhesion [Term] id: CCO:B0001505 name: MYBB_HUMAN def: "Myb-related protein B" [UniProtKB:P10244] synonym: "B-Myb" EXACT [UniProtKB:P10244] xref: EMBL:AAH07585.1 xref: EMBL:AAH53555.1 xref: EMBL:CAA31655.1 xref: EMBL:CAC08392.1 xref: UniProtKB:P10244 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005139 ! MYBL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013049 ! MYBB_HUMAN-Phosphothreonine266 relationship: transforms_into CCO:B0013050 ! MYBB_HUMAN-Phosphoserine393 relationship: transforms_into CCO:B0013051 ! MYBB_HUMAN-Phosphothreonine440 relationship: transforms_into CCO:B0013052 ! MYBB_HUMAN-Phosphothreonine444 relationship: transforms_into CCO:B0013053 ! MYBB_HUMAN-Phosphothreonine487 relationship: transforms_into CCO:B0013054 ! MYBB_HUMAN-Phosphothreonine494 relationship: transforms_into CCO:B0013055 ! MYBB_HUMAN-Phosphothreonine520 relationship: transforms_into CCO:B0013056 ! MYBB_HUMAN-Phosphoserine577 [Term] id: CCO:B0001506 name: BCL2_HUMAN def: "Apoptosis regulator Bcl-2" [UniProtKB:P10415] xref: EMBL:AAA35591.1 xref: EMBL:AAA51813.1 xref: EMBL:AAA51814.1 xref: EMBL:AAD14111.1 xref: EMBL:AAH27258.1 xref: EMBL:AAO26045.1 xref: EMBL:CAA29778.1 xref: UniProtKB:P10415 xref: UniProtKB:P10416 xref: UniProtKB:Q13842 xref: UniProtKB:Q16197 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004151 ! BCL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006207 ! bcl2-bax-2 physical interaction relationship: participates_in CCO:I0006208 ! bcl2-bak-1 physical interaction relationship: participates_in CCO:I0006209 ! bcl2-bad-1 physical interaction relationship: participates_in CCO:I0006210 ! bcl2-bik-1 physical interaction relationship: participates_in CCO:I0006211 ! bcl2-bid-1 physical interaction relationship: participates_in CCO:I0006296 ! bid-bcl2-1 physical interaction relationship: participates_in CCO:I0006883 ! bcl2-bcap31 physical interaction relationship: participates_in CCO:I0006885 ! bcl_2-nip2-1 physical interaction relationship: participates_in CCO:I0006886 ! bcl_2-nip3-1 physical interaction relationship: participates_in CCO:I0006993 ! bnip3alpha-bcl_2-1 direct interaction relationship: participates_in CCO:I0006994 ! bnip3alpha-bcl_2-2 direct interaction relationship: participates_in CCO:I0007129 ! bbc3-bcl2-5 direct interaction relationship: participates_in CCO:I0007130 ! bbc3-bcl2-6 direct interaction relationship: participates_in CCO:I0007132 ! bcap31-bcl2 physical interaction relationship: participates_in CCO:I0007443 ! bad-bcl2-1 physical interaction relationship: participates_in CCO:I0007444 ! bad-bcl2-2 physical interaction relationship: participates_in CCO:I0007445 ! bax-bcl2-1 physical interaction relationship: participates_in CCO:I0007518 ! bcl2-vrk2 physical interaction relationship: participates_in CCO:I0007765 ! bim-bcl2-2 direct interaction relationship: participates_in CCO:I0007766 ! bbc3-bcl2-4 direct interaction relationship: participates_in CCO:I0007767 ! bad-bcl2-3 direct interaction relationship: participates_in CCO:I0007879 ! bcl2-bcl2-1 physical interaction relationship: participates_in CCO:I0007880 ! bcl2_bcl2_human direct interaction relationship: participates_in CCO:I0007881 ! bad_bcl2_human direct interaction relationship: participates_in CCO:I0007882 ! bid_bcl2_human direct interaction relationship: participates_in CCO:I0007883 ! puma_bcl2_human direct interaction relationship: participates_in CCO:I0007884 ! bim_bcl2_human direct interaction relationship: participates_in CCO:I0007933 ! bcl2-bid direct interaction relationship: participates_in CCO:I0007935 ! bcl2-bik direct interaction relationship: participates_in CCO:I0007936 ! bcl2-bbc3 direct interaction relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002040 ! B cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0003162 ! negative regulation of mitochondrial depolarization relationship: transforms_into CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 [Term] id: CCO:B0001507 name: TGFB3_HUMAN def: "Transforming growth factor beta-3 precursor" [UniProtKB:P10600] synonym: "TGF-beta-3" EXACT [UniProtKB:P10600] xref: EMBL:AAA61161.1 xref: EMBL:AAC79727.1 xref: EMBL:AAM96819.1 xref: EMBL:AAO13495.1 xref: EMBL:CAA32362.1 xref: EMBL:CAA33024.1 xref: UniProtKB:P10600 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005775 ! TGFB3_human relationship: has_function CCO:F0001462 ! transforming growth factor beta receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:I0007826 ! tgfb3-tgfbr2-1 direct interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000724 ! SMAD protein nuclear translocation relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001273 ! negative regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0001508 name: CD28_HUMAN def: "T-cell-specific surface glycoprotein CD28 precursor" [UniProtKB:P10747] synonym: "CD28 antigen" EXACT [UniProtKB:P10747] synonym: "TP44" EXACT [UniProtKB:P10747] xref: EMBL:AAA51944.1 xref: EMBL:AAA51945.1 xref: EMBL:AAA60581.1 xref: EMBL:AAF33792.1 xref: EMBL:AAF33793.1 xref: EMBL:AAF33794.1 xref: EMBL:AAH93698.1 xref: EMBL:AAI12086.1 xref: EMBL:AAL40931.1 xref: EMBL:AAY24123.1 xref: EMBL:ABK41938.1 xref: EMBL:CAC29237.1 xref: UniProtKB:P10747 xref: UniProtKB:Q13964 xref: UniProtKB:Q52M23 xref: UniProtKB:Q8NI54 xref: UniProtKB:Q8NI55 xref: UniProtKB:Q8NI56 xref: UniProtKB:Q8WXJ2 xref: UniProtKB:Q9BYV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004270 ! CD28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002524 ! positive regulation of translation relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis relationship: transforms_into CCO:B0011014 ! CD28_HUMAN-Phosphotyrosine191 relationship: transforms_into CCO:B0011015 ! CD28_HUMAN-Phosphotyrosine209 [Term] id: CCO:B0001509 name: FGF6_HUMAN def: "Fibroblast growth factor 6 precursor" [UniProtKB:P10767] synonym: "FGF-6" EXACT [UniProtKB:P10767] synonym: "HBGF-6" EXACT [UniProtKB:P10767] synonym: "Heparin-binding growth factor 6" EXACT [UniProtKB:P10767] synonym: "HST-2" EXACT [UniProtKB:P10767] xref: EMBL:AAI21098.1 xref: EMBL:AAI21099.1 xref: EMBL:AAS79318.1 xref: EMBL:CAA40358.1 xref: EMBL:CAA40359.1 xref: EMBL:CAA40360.1 xref: EMBL:CAA45054.1 xref: EMBL:CAB37648.2 xref: UniProtKB:P10767 xref: UniProtKB:Q0VAE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004637 ! FGF6_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0001510 name: IRF1_HUMAN def: "Interferon regulatory factor 1" [UniProtKB:P10914] synonym: "IRF-1" EXACT [UniProtKB:P10914] xref: EMBL:AAA36043.1 xref: EMBL:AAH09483.1 xref: EMBL:AAV38561.1 xref: EMBL:CAA32624.1 xref: UniProtKB:P10914 xref: UniProtKB:Q96GG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004903 ! IRF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002276 ! positive regulation of interleukin-12 biosynthetic process relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0001511 name: FGF3_HUMAN def: "INT-2 proto-oncogene protein precursor" [UniProtKB:P11487] synonym: "FGF-3" EXACT [UniProtKB:P11487] synonym: "Fibroblast growth factor 3" EXACT [UniProtKB:P11487] synonym: "HBGF-3" EXACT [UniProtKB:P11487] synonym: "Heparin-binding growth factor 3" EXACT [UniProtKB:P11487] xref: EMBL:AAI13740.1 xref: EMBL:CAA32615.1 xref: UniProtKB:P11487 xref: UniProtKB:Q0VG69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004634 ! FGF3_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0001512 name: CDK4_HUMAN def: "Cell division protein kinase 4" [UniProtKB:P11802] synonym: "Cyclin-dependent kinase 4" EXACT [UniProtKB:P11802] synonym: "EC 2.7.11.22" EXACT [UniProtKB:P11802] synonym: "PSK-J3" EXACT [UniProtKB:P11802] xref: EMBL:AAA35673.1 xref: EMBL:AAC39521.2 xref: EMBL:AAC50506.1 xref: EMBL:AAD13991.1 xref: EMBL:AAH03644.1 xref: EMBL:AAH05864.1 xref: EMBL:AAH10153.1 xref: EMBL:AAM23014.1 xref: EMBL:CAA88834.1 xref: UniProtKB:O00576 xref: UniProtKB:P11802 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004301 ! CDK4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005779 ! cdk4-cdkn2d physical interaction relationship: participates_in CCO:I0005885 ! c6orf55-cdk4 physical interaction relationship: participates_in CCO:I0005946 ! cdk4-cdkn2b-1 physical interaction relationship: participates_in CCO:I0005957 ! ccnd3-cdk4 physical interaction relationship: participates_in CCO:I0005999 ! cdc37-cdk4 physical interaction relationship: participates_in CCO:I0006058 ! cdknib-cdk4 physical interaction relationship: participates_in CCO:I0006113 ! cdk4-cdkn2a direct interaction relationship: participates_in CCO:I0006129 ! cdk4-ccnd3 direct interaction relationship: participates_in CCO:I0006130 ! mcm2-cdk4 direct interaction relationship: participates_in CCO:I0006134 ! cdk4-ccnd1 direct interaction relationship: participates_in CCO:I0006152 ! cdkn1a-cdk4 direct interaction relationship: participates_in CCO:I0006162 ! cdc7-cdk4 direct interaction relationship: participates_in CCO:I0006525 ! zn655-cdk4-2 physical interaction relationship: participates_in CCO:I0006526 ! zn655-cdk4-3 physical interaction relationship: participates_in CCO:I0006609 ! cdk4-cdc37-1 physical interaction relationship: participates_in CCO:I0006737 ! ccnd2-cdk4-1 physical interaction relationship: participates_in CCO:I0006738 ! ccnd2-cdk4-2 physical interaction relationship: participates_in CCO:I0006862 ! cdk4-ccnd1-5 physical interaction relationship: participates_in CCO:I0007090 ! cdk4-ccnd1-3 physical interaction relationship: participates_in CCO:I0007248 ! cdk4-ccnd1-6 physical interaction relationship: participates_in CCO:I0007392 ! cdk4-cdc37 physical interaction relationship: participates_in CCO:I0007424 ! zn655-cdk4-1 physical interaction relationship: participates_in CCO:I0007544 ! cdk4-ccnd1-1 physical interaction relationship: participates_in CCO:I0007545 ! cdk4-ccnd1-2 physical interaction relationship: participates_in CCO:I0007546 ! cdk4-cdkn1c-1 physical interaction relationship: participates_in CCO:I0007547 ! cdk4-cdkn1b-1 physical interaction relationship: participates_in CCO:I0007548 ! cdk4-cdkn1a-1 physical interaction relationship: participates_in CCO:I0007549 ! cdk4-ccnd3-1 physical interaction relationship: participates_in CCO:I0007550 ! cdk4-ccnd3-2 physical interaction relationship: participates_in CCO:I0007739 ! cdk4-ccnd1-4 physical interaction relationship: participates_in CCO:I0007854 ! cdkn1a-ccnd1-2 physical interaction relationship: participates_in CCO:I0007902 ! cyclind1_cdk4_human direct interaction relationship: participates_in CCO:I0007903 ! cyclind2_cdk4_human direct interaction relationship: participates_in CCO:I0007904 ! cyclind3_cdk4_human direct interaction relationship: participates_in CCO:I0007981 ! cdk4-cdkn2b physical interaction relationship: participates_in CCO:I0008004 ! cdk4-capns1 physical interaction relationship: participates_in CCO:I0008079 ! cdk4-bat3 physical interaction relationship: participates_in CCO:I0008080 ! cdk4-setdb1 physical interaction relationship: participates_in CCO:I0008484 ! mgc3731-cdk4 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000947 ! regulation of gene expression relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011112 ! CDK4_HUMAN-Phosphothreonine172 [Term] id: CCO:B0001513 name: PCNA_HUMAN def: "Proliferating cell nuclear antigen" [UniProtKB:P12004] synonym: "Cyclin" EXACT [UniProtKB:P12004] synonym: "PCNA" EXACT [UniProtKB:P12004] xref: EMBL:AAA35736.1 xref: EMBL:AAA60040.1 xref: EMBL:AAH00491.1 xref: EMBL:AAH62439.1 xref: EMBL:AAM78556.1 xref: EMBL:CAC27344.1 xref: UniProtKB:P12004 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005278 ! PCNA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004392 ! DNA polymerase processivity factor activity relationship: has_function CCO:F0004985 ! MutLalpha complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000261 ! nuclear lamina relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000265 ! replication fork relationship: located_in CCO:C0000268 ! DNA replication factor C complex relationship: located_in CCO:C0001801 ! PCNA complex relationship: participates_in CCO:I0005962 ! cdkn1a-pcna physical interaction relationship: participates_in CCO:I0005986 ! pcna-pold1-1 physical interaction relationship: participates_in CCO:I0005987 ! pcna-pold1-2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000639 ! regulation of DNA replication relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0001514 name: FGF5_HUMAN def: "Fibroblast growth factor 5 precursor" [UniProtKB:P12034] synonym: "FGF-5" EXACT [UniProtKB:P12034] synonym: "HBGF-5" EXACT [UniProtKB:P12034] synonym: "Heparin-binding growth factor 5" EXACT [UniProtKB:P12034] synonym: "Smag-82" EXACT [UniProtKB:P12034] xref: EMBL:AAB06463.1 xref: EMBL:AAB60698.1 xref: EMBL:AAB60699.1 xref: EMBL:AAF89742.1 xref: EMBL:AAZ67914.1 xref: EMBL:BAA33738.1 xref: UniProtKB:O75846 xref: UniProtKB:P12034 xref: UniProtKB:Q3Y8M3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004636 ! FGF5_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0001515 name: BMP2_HUMAN def: "Bone morphogenetic protein 2 precursor" [UniProtKB:P12643] synonym: "BMP-2" EXACT [UniProtKB:P12643] synonym: "BMP-2A" EXACT [UniProtKB:P12643] xref: EMBL:AAA51834.1 xref: EMBL:AAF21646.1 xref: EMBL:CAB82007.1 xref: UniProtKB:P12643 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004170 ! BMP2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0006232 ! bmp2-bmpr1a-1 direct interaction relationship: participates_in CCO:I0007709 ! bmp2-bmpr1a-2 direct interaction relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001643 ! negative regulation of gene-specific transcription relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002883 ! positive regulation of astrocyte differentiation [Term] id: CCO:B0001516 name: BMP4_HUMAN def: "Bone morphogenetic protein 4 precursor" [UniProtKB:P12644] synonym: "BMP-2B" EXACT [UniProtKB:P12644] synonym: "BMP-4" EXACT [UniProtKB:P12644] xref: EMBL:AAA51835.1 xref: EMBL:AAC72278.1 xref: EMBL:AAH20546.1 xref: EMBL:BAA06410.1 xref: UniProtKB:P12644 xref: UniProtKB:Q9UM80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004171 ! BMP4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001594 ! negative regulation of chondrocyte differentiation relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation relationship: participates_in CCO:P0002476 ! negative regulation of myoblast differentiation relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation [Term] id: CCO:B0001517 name: IFM1_HUMAN def: "Interferon-induced transmembrane protein 1" [UniProtKB:P13164] synonym: "CD225 antigen" EXACT [UniProtKB:P13164] synonym: "Interferon-induced protein 17" EXACT [UniProtKB:P13164] synonym: "Interferon-inducible protein 9-27" EXACT [UniProtKB:P13164] synonym: "Leu-13 antigen" EXACT [UniProtKB:P13164] xref: EMBL:AAA35494.1 xref: EMBL:AAH00897.1 xref: EMBL:CAA59337.1 xref: UniProtKB:P13164 xref: UniProtKB:Q15322 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004865 ! IFITM1_human relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007335 ! bat5-ifitm1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001518 name: HGF_HUMAN def: "Hepatocyte growth factor precursor" [UniProtKB:P14210] synonym: "Hepatopoeitin-A" EXACT [UniProtKB:P14210] synonym: "Scatter factor" EXACT [UniProtKB:P14210] synonym: "SF" EXACT [UniProtKB:P14210] xref: EMBL:AAA35980.1 xref: EMBL:AAA52648.1 xref: EMBL:AAA52649.1 xref: EMBL:AAA52650.1 xref: EMBL:AAA64239.1 xref: EMBL:AAA64297.1 xref: EMBL:AAC50539.1 xref: EMBL:AAC71655.1 xref: EMBL:AAG53459.1 xref: EMBL:AAG53460.1 xref: EMBL:AAH22308.1 xref: EMBL:AAH63485.1 xref: EMBL:AAI30285.1 xref: EMBL:AAI30287.1 xref: EMBL:AAO61091.1 xref: EMBL:BAA14348.1 xref: EMBL:CAA34387.1 xref: EMBL:CAA40802.1 xref: EMBL:EAL24189.1 xref: UniProtKB:A1L3U6 xref: UniProtKB:P14210 xref: UniProtKB:Q02935 xref: UniProtKB:Q13494 xref: UniProtKB:Q14519 xref: UniProtKB:Q8TCE2 xref: UniProtKB:Q9BYL9 xref: UniProtKB:Q9BYM0 xref: UniProtKB:Q9UDU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004803 ! HGF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006236 ! hgf-met-1 direct interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: transforms_into CCO:B0012184 ! HGF_HUMAN-Pyrrolidone carboxylic acid32 [Term] id: CCO:B0001519 name: CCNB1_HUMAN def: "G2/mitotic-specific cyclin-B1" [UniProtKB:P14635] xref: EMBL:AAH06510.1 xref: EMBL:AAP88038.1 xref: UniProtKB:P14635 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004244 ! CCNB1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006292 ! cdkn1b-ccnb1-1 physical interaction relationship: participates_in CCO:I0006861 ! cdc2-ccnb1-1 physical interaction relationship: participates_in CCO:I0007244 ! pkmyt1-ccnb1-1 physical interaction relationship: participates_in CCO:I0007245 ! ccnb1-pkmyt1-1 physical interaction relationship: participates_in CCO:I0007899 ! cyclinb1_cdk1_human direct interaction relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001520 name: ERF3A_HUMAN def: "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A" [UniProtKB:P15170] synonym: "eRF3a" EXACT [UniProtKB:P15170] synonym: "Eukaryotic peptide chain release factor subunit 3a" EXACT [UniProtKB:P15170] synonym: "G1 to S phase transition protein 1 homolog" EXACT [UniProtKB:P15170] xref: EMBL:AAB67250.1 xref: EMBL:CAA35635.1 xref: UniProtKB:P15170 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004735 ! GSPT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000318 ! translation release factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0007625 ! atxn1-gspt1 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0001522 name: FOSL1_HUMAN def: "Fos-related antigen 1" [UniProtKB:P15407] synonym: "FRA-1" EXACT [UniProtKB:P15407] xref: EMBL:AAH16648.1 xref: EMBL:CAA34679.1 xref: EMBL:CAC50237.1 xref: UniProtKB:P15407 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004653 ! FOSL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005759 ! fosl1-ldoc1 physical interaction relationship: participates_in CCO:I0005950 ! fosl1-junb physical interaction relationship: participates_in CCO:P0000269 ! positive regulation of transcription from RNA polymerase II promoter, mitotic relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001523 name: PGDH_HUMAN def: "15-hydroxyprostaglandin dehydrogenase [NAD+]" [UniProtKB:P15428] synonym: "EC 1.1.1.141" EXACT [UniProtKB:P15428] synonym: "PGDH" EXACT [UniProtKB:P15428] synonym: "Prostaglandin dehydrogenase 1" EXACT [UniProtKB:P15428] xref: EMBL:AAA89174.1 xref: EMBL:AAA89175.1 xref: EMBL:AAH18986.1 xref: UniProtKB:P15428 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005304 ! HPGD_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003127 ! 15-hydroxyprostaglandin dehydrogenase (NAD+) activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0001524 name: NDKA_HUMAN def: "Nucleoside diphosphate kinase A" [UniProtKB:P15531] synonym: "EC 2.7.4.6" EXACT [UniProtKB:P15531] synonym: "GAAD" EXACT [UniProtKB:P15531] synonym: "Granzyme A-activated DNase" EXACT [UniProtKB:P15531] synonym: "Metastasis inhibition factor nm23" EXACT [UniProtKB:P15531] synonym: "NDK A" EXACT [UniProtKB:P15531] synonym: "NDP kinase A" EXACT [UniProtKB:P15531] synonym: "nm23-H1" EXACT [UniProtKB:P15531] synonym: "Tumor metastatic process-associated protein" EXACT [UniProtKB:P15531] xref: EMBL:AAH00293.1 xref: EMBL:AAH18994.1 xref: EMBL:CAA35621.1 xref: EMBL:CAA51527.1 xref: EMBL:CAA53270.1 xref: UniProtKB:P15531 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005167 ! NME1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000932 ! deoxyribonuclease activity relationship: has_function CCO:F0000936 ! nucleoside diphosphate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005731 ! c8orf32-nme1 physical interaction relationship: participates_in CCO:I0005765 ! nme1-nme4 physical interaction relationship: participates_in CCO:I0005823 ! nme1-polr1c physical interaction relationship: participates_in CCO:I0005832 ! gorasp2-nme1 physical interaction relationship: participates_in CCO:I0005941 ! nme1-nme3 physical interaction relationship: participates_in CCO:I0005955 ! nme1-nme1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0001525 name: VEGFA_HUMAN def: "Vascular endothelial growth factor A precursor" [UniProtKB:P15692] synonym: "Vascular permeability factor" EXACT [UniProtKB:P15692] synonym: "VEGF-A" EXACT [UniProtKB:P15692] synonym: "VPF" EXACT [UniProtKB:P15692] xref: EMBL:AAA35789.1 xref: EMBL:AAA36804.1 xref: EMBL:AAA36807.1 xref: EMBL:AAC16730.1 xref: EMBL:AAC63101.1 xref: EMBL:AAC63102.1 xref: EMBL:AAC63143.1 xref: EMBL:AAD55345.1 xref: EMBL:AAF19659.1 xref: EMBL:AAH65522.2 xref: EMBL:AAK95847.1 xref: EMBL:AAL27435.1 xref: EMBL:AAL27630.1 xref: EMBL:AAM03108.1 xref: EMBL:AAV34601.1 xref: EMBL:ABB58912.1 xref: EMBL:BAA78418.1 xref: EMBL:CAA09179.1 xref: EMBL:CAA44447.1 xref: EMBL:CAC19512.1 xref: EMBL:CAC19513.1 xref: EMBL:CAC19515.1 xref: EMBL:CAC19516.2 xref: UniProtKB:O60720 xref: UniProtKB:O75875 xref: UniProtKB:P15692 xref: UniProtKB:Q074Z4 xref: UniProtKB:Q16889 xref: UniProtKB:Q5UB46 xref: UniProtKB:Q6P0P5 xref: UniProtKB:Q96KJ0 xref: UniProtKB:Q96L82 xref: UniProtKB:Q96NW5 xref: UniProtKB:Q9H1W8 xref: UniProtKB:Q9H1W9 xref: UniProtKB:Q9UH58 xref: UniProtKB:Q9UL23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006373 ! VEGFA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006259 ! nrp1-vegf physical interaction relationship: participates_in CCO:I0007020 ! flt1-vegf-1 direct interaction relationship: participates_in CCO:I0007468 ! flt1-vegf-2 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0001356 ! positive regulation of vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: transforms_into CCO:B0014610 ! VEGFA_HUMAN-N6-acetyllysine147 relationship: transforms_into CCO:B0014611 ! VEGFA_HUMAN-N6-acetyllysine149 relationship: transforms_into CCO:B0014612 ! VEGFA_HUMAN-N6-acetyllysine152 [Term] id: CCO:B0001526 name: H2AX_HUMAN def: "Histone H2A.x" [UniProtKB:P16104] synonym: "H2a/x" EXACT [UniProtKB:P16104] xref: EMBL:AAH04915.1 xref: EMBL:AAH11694.1 xref: EMBL:AAH13416.1 xref: EMBL:AAY22178.1 xref: EMBL:CAA32968.1 xref: EMBL:CAG33360.1 xref: UniProtKB:P16104 xref: UniProtKB:Q4ZGJ7 xref: UniProtKB:Q6IAS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004743 ! H2AFX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000265 ! replication fork relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0006022 ! nbs1-h2afx-2 physical interaction relationship: participates_in CCO:I0006198 ! h2ax-tp53bp1-1 physical interaction relationship: participates_in CCO:I0006514 ! h2afx-nbs1-1 physical interaction relationship: participates_in CCO:I0006515 ! nbs1-h2afx-1 physical interaction relationship: participates_in CCO:I0006517 ! h2afx-mre11a-2 physical interaction relationship: participates_in CCO:I0006518 ! h2afx-nbs1-2 physical interaction relationship: participates_in CCO:I0007342 ! h2afx-nbs1-4 physical interaction relationship: participates_in CCO:I0007538 ! h2afx-nbs1-5 physical interaction relationship: participates_in CCO:I0007850 ! h2afx-mre11a-1 colocalization relationship: participates_in CCO:I0007851 ! h2afx-nbs1-3 physical interaction relationship: participates_in CCO:I0007852 ! h2afx-brca1-1 physical interaction relationship: participates_in CCO:I0008508 ! supt5h-h2afx physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: transforms_into CCO:B0012008 ! H2AX_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0012009 ! H2AX_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0012010 ! H2AX_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0026379 ! H2AX_HUMAN-Phosphothreonine121 [Term] id: CCO:B0001527 name: PP2BB_HUMAN def: "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform" [UniProtKB:P16298] synonym: "Calmodulin-dependent calcineurin A subunit beta isoform" EXACT [UniProtKB:P16298] synonym: "CAM-PRP catalytic subunit" EXACT [UniProtKB:P16298] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P16298] xref: EMBL:AAA35705.1 xref: EMBL:AAA35706.1 xref: EMBL:CAD32694.1 xref: EMBL:CAI52473.1 xref: EMBL:CAI52487.1 xref: EMBL:EAW54498.1 xref: UniProtKB:P16298 xref: UniProtKB:P16299 xref: UniProtKB:Q5F2F9 xref: UniProtKB:Q8N3W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005360 ! PPP3CB_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000504 ! calcineurin complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0001528 name: STMN1_HUMAN def: "Stathmin" [UniProtKB:P16949] synonym: "Leukemia-associated phosphoprotein p18" EXACT [UniProtKB:P16949] synonym: "Metablastin" EXACT [UniProtKB:P16949] synonym: "Oncoprotein 18" EXACT [UniProtKB:P16949] synonym: "Op18" EXACT [UniProtKB:P16949] synonym: "Phosphoprotein p19" EXACT [UniProtKB:P16949] synonym: "pp17" EXACT [UniProtKB:P16949] synonym: "pp19" EXACT [UniProtKB:P16949] synonym: "Prosolin" EXACT [UniProtKB:P16949] synonym: "Protein Pr22" EXACT [UniProtKB:P16949] xref: EMBL:AAA59971.1 xref: EMBL:AAA59980.1 xref: EMBL:AAH82228.1 xref: EMBL:CAA37391.1 xref: EMBL:CAA64398.1 xref: EMBL:CAA77660.1 xref: EMBL:CAC16020.1 xref: UniProtKB:A2A2D1 xref: UniProtKB:P16949 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005696 ! STMN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007611 ! ubqln4-stmn1 physical interaction relationship: participates_in CCO:I0007822 ! stmn1-cdkn1b physical interaction relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0014258 ! STMN1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0014259 ! STMN1_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0014260 ! STMN1_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0014261 ! STMN1_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0014262 ! STMN1_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0014263 ! STMN1_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0014264 ! STMN1_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0014265 ! STMN1_HUMAN-Phosphothreonine146 [Term] id: CCO:B0001529 name: KPCA_HUMAN def: "Protein kinase C alpha type" [UniProtKB:P17252] synonym: "EC 2.7.11.13" EXACT [UniProtKB:P17252] synonym: "PKC-A" EXACT [UniProtKB:P17252] synonym: "PKC-alpha" EXACT [UniProtKB:P17252] xref: EMBL:AAA60098.1 xref: EMBL:AAI09274.1 xref: EMBL:AAI09275.1 xref: EMBL:AAK84184.1 xref: EMBL:CAA36718.1 xref: UniProtKB:P17252 xref: UniProtKB:Q15137 xref: UniProtKB:Q32M72 xref: UniProtKB:Q96RE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004957 ! PRKCA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000501 ! negative regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: participates_in CCO:P0002705 ! negative regulation of insulin receptor signaling pathway relationship: participates_in CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation relationship: transforms_into CCO:B0012619 ! KPCA_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0012620 ! KPCA_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0012621 ! KPCA_HUMAN-Phosphothreonine494 relationship: transforms_into CCO:B0012622 ! KPCA_HUMAN-Phosphothreonine495 relationship: transforms_into CCO:B0012623 ! KPCA_HUMAN-Phosphothreonine497 relationship: transforms_into CCO:B0012624 ! KPCA_HUMAN-Phosphothreonine501 relationship: transforms_into CCO:B0012625 ! KPCA_HUMAN-Phosphothreonine631 relationship: transforms_into CCO:B0012626 ! KPCA_HUMAN-Phosphothreonine638 relationship: transforms_into CCO:B0012627 ! KPCA_HUMAN-Phosphoserine657 relationship: transforms_into CCO:B0012628 ! KPCA_HUMAN-Phosphotyrosine658 relationship: transforms_into CCO:B0067389 ! KPCA_HUMAN-Phosphotyrosine195 [Term] id: CCO:B0001530 name: JUNB_HUMAN def: "Transcription factor jun-B" [UniProtKB:P17275] xref: EMBL:AAA59198.1 xref: EMBL:AAA74915.1 xref: EMBL:AAH04250.1 xref: EMBL:AAH09465.1 xref: EMBL:AAH09466.1 xref: EMBL:AAU43800.1 xref: EMBL:CAA35738.1 xref: UniProtKB:P17275 xref: UniProtKB:Q96GH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004912 ! JUNB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005950 ! fosl1-junb physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000887 ! cellular process relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0012447 ! JUNB_HUMAN-Phosphothreonine255 relationship: transforms_into CCO:B0012448 ! JUNB_HUMAN-Phosphoserine259 [Term] id: CCO:B0001531 name: BMP7_HUMAN def: "Bone morphogenetic protein 7 precursor" [UniProtKB:P18075] synonym: "BMP-7" EXACT [UniProtKB:P18075] synonym: "Eptotermin alfa" EXACT [UniProtKB:P18075] synonym: "OP-1" EXACT [UniProtKB:P18075] synonym: "Osteogenic protein 1" EXACT [UniProtKB:P18075] xref: EMBL:AAA36738.1 xref: EMBL:AAH08584.1 xref: EMBL:CAA36100.1 xref: EMBL:CAB90273.2 xref: EMBL:CAC08434.2 xref: UniProtKB:P18075 xref: UniProtKB:Q9H512 xref: UniProtKB:Q9NTQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004172 ! BMP7_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0005973 ! bmp7-nog-1 direct interaction relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0001532 name: PACA_HUMAN def: "Pituitary adenylate cyclase-activating polypeptide precursor" [UniProtKB:P18509] synonym: "PACAP" EXACT [UniProtKB:P18509] xref: EMBL:AAB21470.1 xref: EMBL:AAH93837.1 xref: EMBL:AAI01804.1 xref: EMBL:CAA42962.1 xref: UniProtKB:P18509 xref: UniProtKB:Q52LQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005254 ! ADCYAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0013373 ! PACA_HUMAN-Leucine amide158 relationship: transforms_into CCO:B0013374 ! PACA_HUMAN-Lysine amide169 [Term] id: CCO:B0001533 name: RCC1_HUMAN def: "Regulator of chromosome condensation" [UniProtKB:P18754] synonym: "Cell cycle regulatory protein" EXACT [UniProtKB:P18754] synonym: "Chromosome condensation protein 1" EXACT [UniProtKB:P18754] xref: EMBL:AAH07300.1 xref: EMBL:AAH10067.1 xref: EMBL:AAH36903.1 xref: EMBL:AAM21072.1 xref: EMBL:BAA00469.1 xref: EMBL:CAA29496.1 xref: EMBL:CAA31182.1 xref: UniProtKB:P18754 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005456 ! RCC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007154 ! ranbp3-rcc1-1 physical interaction relationship: participates_in CCO:I0007155 ! rcc1-xpo1-1 physical interaction relationship: participates_in CCO:I0007298 ! rcc1-ranbp3-1 physical interaction relationship: participates_in CCO:I0007471 ! ran-rcc1-1 direct interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: participates_in CCO:P0000101 ! regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013805 ! RCC1_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0013806 ! RCC1_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0013807 ! RCC1_HUMAN-Phosphoserine405 relationship: transforms_into CCO:B0013808 ! RCC1_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0013809 ! RCC1_HUMAN-Phosphothreonine411 [Term] id: CCO:B0001534 name: DNLI1_HUMAN def: "DNA ligase 1" [UniProtKB:P18858] synonym: "DNA ligase I" EXACT [UniProtKB:P18858] synonym: "EC 6.5.1.1" EXACT [UniProtKB:P18858] synonym: "Polydeoxyribonucleotide synthase [ATP] 1" EXACT [UniProtKB:P18858] xref: EMBL:AAA59518.1 xref: EMBL:AAI08319.1 xref: EMBL:AAM77697.1 xref: UniProtKB:P18858 xref: UniProtKB:Q32P23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004492 ! LIG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008480 ! inpp1-lig1 physical interaction relationship: participates_in CCO:I0008513 ! tubb4-lig1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0064801 ! DNLI1_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0064802 ! DNLI1_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0064803 ! DNLI1_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0064804 ! DNLI1_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0064805 ! DNLI1_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0064806 ! DNLI1_HUMAN-Phosphothreonine195 relationship: transforms_into CCO:B0064807 ! DNLI1_HUMAN-Phosphoserine201 relationship: transforms_into CCO:B0064808 ! DNLI1_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0064809 ! DNLI1_HUMAN-Phosphothreonine233 relationship: transforms_into CCO:B0064810 ! DNLI1_HUMAN-Phosphoserine911 [Term] id: CCO:B0001535 name: E2AK2_HUMAN def: "Interferon-induced, double-stranded RNA-activated protein kinase" [UniProtKB:P19525] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P19525] synonym: "eIF-2A protein kinase 2" EXACT [UniProtKB:P19525] synonym: "Eukaryotic translation initiation factor 2-alpha kinase 2" EXACT [UniProtKB:P19525] synonym: "Interferon-inducible RNA-dependent protein kinase" EXACT [UniProtKB:P19525] synonym: "P1/eIF-2A protein kinase" EXACT [UniProtKB:P19525] synonym: "p68 kinase" EXACT [UniProtKB:P19525] synonym: "PKR" EXACT [UniProtKB:P19525] synonym: "Protein kinase RNA-activated" EXACT [UniProtKB:P19525] xref: EMBL:AAA18253.1 xref: EMBL:AAA36409.1 xref: EMBL:AAC50768.1 xref: EMBL:AAF13156.1 xref: EMBL:AAH93676.1 xref: EMBL:AAI01476.1 xref: EMBL:AAO38055.1 xref: EMBL:AAY24317.1 xref: UniProtKB:P19525 xref: UniProtKB:Q52M43 xref: UniProtKB:Q9UIR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004531 ! EIF2AK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: transforms_into CCO:B0011611 ! E2AK2_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0011612 ! E2AK2_HUMAN-Phosphothreonine88 relationship: transforms_into CCO:B0011613 ! E2AK2_HUMAN-Phosphothreonine89 relationship: transforms_into CCO:B0011614 ! E2AK2_HUMAN-Phosphothreonine90 relationship: transforms_into CCO:B0011615 ! E2AK2_HUMAN-Phosphoserine242 relationship: transforms_into CCO:B0011616 ! E2AK2_HUMAN-Phosphothreonine255 relationship: transforms_into CCO:B0011617 ! E2AK2_HUMAN-Phosphothreonine258 relationship: transforms_into CCO:B0011618 ! E2AK2_HUMAN-Phosphothreonine446 relationship: transforms_into CCO:B0011619 ! E2AK2_HUMAN-Phosphothreonine451 [Term] id: CCO:B0001536 name: WT1_HUMAN def: "Wilms tumor protein" [UniProtKB:P19544] synonym: "WT33" EXACT [UniProtKB:P19544] xref: EMBL:AAA36810.1 xref: EMBL:AAA61299.1 xref: EMBL:AAB20110.1 xref: EMBL:AAB20111.1 xref: EMBL:AAB20112.1 xref: EMBL:AAB33443.1 xref: EMBL:AAC60605.1 xref: EMBL:AAH32861.1 xref: EMBL:AAO61088.1 xref: EMBL:CAA35956.1 xref: EMBL:CAA43819.1 xref: EMBL:CAC39220.2 xref: UniProtKB:P19544 xref: UniProtKB:Q15881 xref: UniProtKB:Q16256 xref: UniProtKB:Q16575 xref: UniProtKB:Q8IYZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005934 ! WT1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001537 name: CSK22_HUMAN def: "Casein kinase II subunit alpha'" [UniProtKB:P19784] synonym: "CK II" EXACT [UniProtKB:P19784] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P19784] xref: EMBL:AAA51548.1 xref: EMBL:AAH08812.1 xref: UniProtKB:P19784 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004403 ! CSNK2A2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001052 ! protein kinase CK2 activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007336 ! csnk2b-csnk2a2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0001538 name: CCNA2_HUMAN def: "Cyclin-A2" [UniProtKB:P20248] synonym: "Cyclin-A" EXACT [UniProtKB:P20248] xref: EMBL:AAI04784.1 xref: EMBL:AAI04788.1 xref: EMBL:AAM54042.1 xref: EMBL:AAY40969.1 xref: EMBL:CAA35986.1 xref: EMBL:CAA48375.1 xref: EMBL:CAG28620.1 xref: UniProtKB:P20248 xref: UniProtKB:Q2M3U6 xref: UniProtKB:Q4W5P4 xref: UniProtKB:Q6LER8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004243 ! CCNA2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000190 ! female pronucleus relationship: located_in CCO:C0000191 ! male pronucleus relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006020 ! orc1-cdk2-1 physical interaction relationship: participates_in CCO:I0006021 ! orc1-orc2-1 physical interaction relationship: participates_in CCO:I0006332 ! ccna2_cdk2-1 direct interaction relationship: participates_in CCO:I0006451 ! ccna2-cdk2-10 direct interaction relationship: participates_in CCO:I0006452 ! ccna2-cdk2-11 direct interaction relationship: participates_in CCO:I0006563 ! ccna2-cdk2-2 direct interaction relationship: participates_in CCO:I0006570 ! dtnbp1-ccna2 physical interaction relationship: participates_in CCO:I0006770 ! ccna2-cdk2-3 direct interaction relationship: participates_in CCO:I0006798 ! ccna2-cdk2-8 direct interaction relationship: participates_in CCO:I0006945 ! cdkn1b-abl-2 phosphorylation relationship: participates_in CCO:I0007057 ! cdkn1b-cdk2-2 physical interaction relationship: participates_in CCO:I0007059 ! cdkn1b-ccna1-1 direct interaction relationship: participates_in CCO:I0007323 ! cdkn1b-cdk2-4 physical interaction relationship: participates_in CCO:I0007487 ! cdkn1b-cdk2-1 physical interaction relationship: participates_in CCO:I0007488 ! cdkn1b-cdk2-5 phosphorylation relationship: participates_in CCO:I0007499 ! ccna2-cdk2-4 direct interaction relationship: participates_in CCO:I0007500 ! ccna2-cdk2-5 direct interaction relationship: participates_in CCO:I0007501 ! ccna2-cdk2-6 direct interaction relationship: participates_in CCO:I0007502 ! ccna2-cdk2-7 direct interaction relationship: participates_in CCO:I0007533 ! cdt1-cdk2-1 physical interaction relationship: participates_in CCO:I0007825 ! ccna2-cdk2-1 physical interaction relationship: participates_in CCO:I0007896 ! cyclina2_cdk1_human direct interaction relationship: participates_in CCO:I0007898 ! cyclina2_cdk2_human direct interaction relationship: participates_in CCO:I0007941 ! ccna2-cdk2-9 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000106 ! mitotic cell cycle G2/M transition DNA damage checkpoint relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001539 name: PTMS_HUMAN def: "Parathymosin" [UniProtKB:P20962] xref: EMBL:AAA61185.1 xref: UniProtKB:P20962 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005398 ! PTMS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008452 ! c7orf20-ptms physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0013649 ! PTMS_HUMAN-N-acetylserine2 [Term] id: CCO:B0001540 name: CD2L1_HUMAN def: "PITSLRE serine/threonine-protein kinase CDC2L1" [UniProtKB:P21127] synonym: "CDK11" EXACT [UniProtKB:P21127] synonym: "Cell division cycle 2-like protein kinase 1" EXACT [UniProtKB:P21127] synonym: "CLK-1" EXACT [UniProtKB:P21127] synonym: "EC 2.7.11.22" EXACT [UniProtKB:P21127] synonym: "Galactosyltransferase-associated protein kinase p58/GTA" EXACT [UniProtKB:P21127] synonym: "p58 CLK-1" EXACT [UniProtKB:P21127] xref: EMBL:AAA19581.1 xref: EMBL:AAA19582.1 xref: EMBL:AAA19583.1 xref: EMBL:AAA19584.1 xref: EMBL:AAA19586.1 xref: EMBL:AAA36406.1 xref: EMBL:AAB59449.1 xref: EMBL:AAC72077.1 xref: EMBL:AAC72078.1 xref: EMBL:AAC72079.1 xref: EMBL:AAC72080.1 xref: EMBL:AAC72081.1 xref: EMBL:AAC72082.1 xref: EMBL:AAC83662.1 xref: EMBL:AAC83663.1 xref: EMBL:AAC83664.1 xref: EMBL:AAC83665.1 xref: EMBL:AAC83666.1 xref: EMBL:AAF36538.1 xref: EMBL:AAH33069.1 xref: UniProtKB:O95265 xref: UniProtKB:P21127 xref: UniProtKB:Q12817 xref: UniProtKB:Q12818 xref: UniProtKB:Q12819 xref: UniProtKB:Q12820 xref: UniProtKB:Q12822 xref: UniProtKB:Q8N530 xref: UniProtKB:Q9NZS5 xref: UniProtKB:Q9UBJ0 xref: UniProtKB:Q9UBQ1 xref: UniProtKB:Q9UBR0 xref: UniProtKB:Q9UNY2 xref: UniProtKB:Q9UP57 xref: UniProtKB:Q9UP58 xref: UniProtKB:Q9UP59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004273 ! CDC2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006266 ! cdc2l1-pak1-1 physical interaction relationship: participates_in CCO:I0006667 ! cdc2l1-pak1-ac-vit physical interaction relationship: participates_in CCO:I0007946 ! cdc2l1-pak1-2 physical interaction relationship: participates_in CCO:I0008453 ! cdc2l1-c9orf74 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002925 ! regulation of mRNA processing relationship: transforms_into CCO:B0011018 ! CD2L1_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0011019 ! CD2L1_HUMAN-Phosphothreonine448 relationship: transforms_into CCO:B0011020 ! CD2L1_HUMAN-Phosphotyrosine449 relationship: transforms_into CCO:B0011021 ! CD2L1_HUMAN-Phosphoserine589 relationship: transforms_into CCO:B0011022 ! CD2L1_HUMAN-Phosphothreonine595 relationship: transforms_into CCO:B0011023 ! CD2L1_HUMAN-Phosphothreonine751 relationship: transforms_into CCO:B0011024 ! CD2L1_HUMAN-Phosphoserine752 [Term] id: CCO:B0001541 name: PTN_HUMAN def: "Pleiotrophin precursor" [UniProtKB:P21246] synonym: "HB-GAM" EXACT [UniProtKB:P21246] synonym: "HBBM" EXACT [UniProtKB:P21246] synonym: "HBGF-8" EXACT [UniProtKB:P21246] synonym: "HBNF-1" EXACT [UniProtKB:P21246] synonym: "Heparin-binding brain mitogen" EXACT [UniProtKB:P21246] synonym: "Heparin-binding growth factor 8" EXACT [UniProtKB:P21246] synonym: "Heparin-binding growth-associated molecule" EXACT [UniProtKB:P21246] synonym: "Heparin-binding neurite outgrowth-promoting factor 1" EXACT [UniProtKB:P21246] synonym: "OSF-1" EXACT [UniProtKB:P21246] synonym: "Osteoblast-specific factor 1" EXACT [UniProtKB:P21246] synonym: "PTN" EXACT [UniProtKB:P21246] xref: EMBL:AAA35961.1 xref: EMBL:AAB24425.1 xref: EMBL:AAB26456.1 xref: EMBL:AAH05916.1 xref: EMBL:BAA14261.1 xref: EMBL:BAA22944.1 xref: EMBL:CAA37121.1 xref: UniProtKB:P21246 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005400 ! PTN_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:I0006177 ! bard1-ptn physical interaction relationship: participates_in CCO:I0006189 ! kpnb1-ptn physical interaction relationship: participates_in CCO:I0006191 ! gadd45g-ptn physical interaction relationship: participates_in CCO:I0006192 ! ptn-fez1 physical interaction relationship: participates_in CCO:I0006193 ! ptn-ptn physical interaction relationship: participates_in CCO:I0006194 ! pias4-ptn physical interaction relationship: participates_in CCO:I0006195 ! ptn-gprasp2 physical interaction relationship: participates_in CCO:I0007610 ! ubqln4-ptn-1 physical interaction relationship: participates_in CCO:I0007979 ! ubqln4-ptn physical interaction relationship: participates_in CCO:I0007988 ! psmd2-ptn physical interaction relationship: participates_in CCO:I0007989 ! ptn-chd3 physical interaction relationship: participates_in CCO:I0007992 ! sgta-ptn physical interaction relationship: participates_in CCO:I0007994 ! arih2-ptn physical interaction relationship: participates_in CCO:I0008013 ! gnb2l1-ptn physical interaction relationship: participates_in CCO:I0008019 ! loc51236-ptn physical interaction relationship: participates_in CCO:I0008034 ! ppp2ca-ptn physical interaction relationship: participates_in CCO:I0008035 ! psmd11-ptn physical interaction relationship: participates_in CCO:I0008040 ! ptprs-ptn physical interaction relationship: participates_in CCO:I0008045 ! rplp1-ptn physical interaction relationship: participates_in CCO:I0008061 ! tomm20-ptn physical interaction relationship: participates_in CCO:I0008070 ! atp5c1-ptn physical interaction relationship: participates_in CCO:I0008074 ! capzb-ptn physical interaction relationship: participates_in CCO:I0008090 ! creld1-ptn physical interaction relationship: participates_in CCO:I0008099 ! dnajb11-ptn physical interaction relationship: participates_in CCO:I0008102 ! eif3s5-ptn physical interaction relationship: participates_in CCO:I0008110 ! gpd1-ptn physical interaction relationship: participates_in CCO:I0008115 ! gstp1-ptn physical interaction relationship: participates_in CCO:I0008128 ! lama4-ptn physical interaction relationship: participates_in CCO:I0008129 ! luc7l2-ptn physical interaction relationship: participates_in CCO:I0008132 ! mad2l1bp-ptn physical interaction relationship: participates_in CCO:I0008139 ! p4hb-ptn physical interaction relationship: participates_in CCO:I0008160 ! crlz1-ptn physical interaction relationship: participates_in CCO:I0008161 ! sat-ptn physical interaction relationship: participates_in CCO:I0008167 ! ssr1-ptn physical interaction relationship: participates_in CCO:I0008180 ! tp53bp2-ptn physical interaction relationship: participates_in CCO:I0008196 ! atrx-ptn physical interaction relationship: participates_in CCO:I0008201 ! bmi1-ptn physical interaction relationship: participates_in CCO:I0008204 ! btbd2-ptn physical interaction relationship: participates_in CCO:I0008208 ! c9orf82-ptn physical interaction relationship: participates_in CCO:I0008209 ! cacnb4-ptn physical interaction relationship: participates_in CCO:I0008210 ! cdh10-ptn physical interaction relationship: participates_in CCO:I0008211 ! cdk5rap2-ptn physical interaction relationship: participates_in CCO:I0008216 ! cox6c-ptn physical interaction relationship: participates_in CCO:I0008224 ! dusp12-ptn physical interaction relationship: participates_in CCO:I0008233 ! flj13391-ptn physical interaction relationship: participates_in CCO:I0008243 ! ftl-ptn physical interaction relationship: participates_in CCO:I0008245 ! bloc1s1-ptn physical interaction relationship: participates_in CCO:I0008246 ! glyat-ptn physical interaction relationship: participates_in CCO:I0008247 ! gtf2f1-ptn physical interaction relationship: participates_in CCO:I0008253 ! itsn2-ptn physical interaction relationship: participates_in CCO:I0008266 ! mllt3-ptn physical interaction relationship: participates_in CCO:I0008277 ! mycbp-ptn physical interaction relationship: participates_in CCO:I0008278 ! nap1l5-ptn physical interaction relationship: participates_in CCO:I0008293 ! pmf1-ptn physical interaction relationship: participates_in CCO:I0008300 ! psmb10-ptn physical interaction relationship: participates_in CCO:I0008313 ! rit1-ptn physical interaction relationship: participates_in CCO:I0008316 ! rnpc4-ptn physical interaction relationship: participates_in CCO:I0008322 ! sncaip-ptn physical interaction relationship: participates_in CCO:I0008325 ! stc2-ptn physical interaction relationship: participates_in CCO:I0008333 ! tac3-ptn physical interaction relationship: participates_in CCO:I0008354 ! apobec3g-ptn physical interaction relationship: participates_in CCO:I0008374 ! cga-ptn physical interaction relationship: participates_in CCO:I0008380 ! dfna5-ptn physical interaction relationship: participates_in CCO:I0008406 ! mkks-ptn physical interaction relationship: participates_in CCO:I0008418 ! plxnb2-ptn physical interaction relationship: participates_in CCO:I0008433 ! supt7l-ptn physical interaction relationship: participates_in CCO:I0008446 ! wfdc2-ptn physical interaction relationship: participates_in CCO:I0008464 ! csta-ptn physical interaction relationship: participates_in CCO:I0008506 ! spin-ptn physical interaction relationship: participates_in CCO:P0000725 ! transmembrane receptor protein tyrosine phosphatase signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001542 name: NF1_HUMAN def: "Neurofibromin" [UniProtKB:P21359] synonym: "Neurofibromatosis-related protein NF-1" EXACT [UniProtKB:P21359] xref: EMBL:AAA18483.1 xref: EMBL:AAA59921.1 xref: EMBL:AAA59922.1 xref: EMBL:AAA59923.1 xref: EMBL:AAA59924.1 xref: EMBL:AAA59925.1 xref: EMBL:AAA59928.1 xref: EMBL:AAA74897.1 xref: EMBL:AAB24636.1 xref: EMBL:AAB48373.1 xref: EMBL:AAB48374.1 xref: EMBL:AAB48375.1 xref: EMBL:AAB48376.1 xref: EMBL:AAB48377.1 xref: EMBL:AAB48378.1 xref: EMBL:AAB48379.1 xref: EMBL:AAB48380.1 xref: EMBL:AAB59558.1 xref: EMBL:AAV50004.1 xref: EMBL:BAA01371.1 xref: EMBL:BAA02150.1 xref: EMBL:CAA69179.1 xref: UniProtKB:O00662 xref: UniProtKB:P21359 xref: UniProtKB:Q14284 xref: UniProtKB:Q14930 xref: UniProtKB:Q9UMK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005186 ! NF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006248 ! nf1-sdc2 physical interaction relationship: participates_in CCO:I0006249 ! nf1-sdc2-1 physical interaction relationship: participates_in CCO:I0006250 ! nf1-sdc2-3 physical interaction relationship: participates_in CCO:I0006251 ! nf1-sdc2-4 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0000507 ! regulation of cell-matrix adhesion relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000794 ! negative regulation of neuroblast proliferation relationship: participates_in CCO:P0001084 ! phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001589 ! regulation of Ras GTPase activity relationship: participates_in CCO:P0001591 ! positive regulation of Ras GTPase activity relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002210 ! negative regulation of MAPKKK cascade relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis relationship: participates_in CCO:P0002236 ! regulation of blood vessel endothelial cell migration relationship: participates_in CCO:P0002493 ! regulation of glial cell differentiation relationship: participates_in CCO:P0002887 ! negative regulation of oligodendrocyte differentiation relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0013159 ! NF1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013160 ! NF1_HUMAN-Phosphoserine864 relationship: transforms_into CCO:B0013161 ! NF1_HUMAN-Phosphoserine2188 relationship: transforms_into CCO:B0013162 ! NF1_HUMAN-Phosphothreonine2514 relationship: transforms_into CCO:B0013163 ! NF1_HUMAN-Phosphoserine2515 relationship: transforms_into CCO:B0026382 ! NF1_HUMAN-Phosphoserine2829 relationship: transforms_into CCO:B0048336 ! NF1_HUMAN-Phosphotyrosine2577 relationship: transforms_into CCO:B0068590 ! NF1_HUMAN-Phosphotyrosine2476 [Term] id: CCO:B0001543 name: TAF1_HUMAN def: "Transcription initiation factor TFIID subunit 1" [UniProtKB:P21675] synonym: "Cell cycle gene 1 protein" EXACT [UniProtKB:P21675] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P21675] synonym: "p250" EXACT [UniProtKB:P21675] synonym: "TAF(II)250" EXACT [UniProtKB:P21675] synonym: "TAFII-250" EXACT [UniProtKB:P21675] synonym: "TAFII250" EXACT [UniProtKB:P21675] synonym: "TBP-associated factor 250 kDa" EXACT [UniProtKB:P21675] synonym: "Transcription initiation factor TFIID 250 kDa subunit" EXACT [UniProtKB:P21675] xref: EMBL:AAT38105.1 xref: EMBL:BAA14374.1 xref: EMBL:BAD92553.1 xref: EMBL:CAA30073.1 xref: EMBL:CAD70490.1 xref: EMBL:CAD70491.3 xref: EMBL:CAD70492.2 xref: EMBL:CAD70493.3 xref: EMBL:CAD87527.2 xref: EMBL:CAD87528.2 xref: EMBL:CAM98557.1 xref: UniProtKB:A5CVD0 xref: UniProtKB:P21675 xref: UniProtKB:Q59FZ3 xref: UniProtKB:Q6IUZ1 xref: UniProtKB:Q70Q86 xref: UniProtKB:Q70Q87 xref: UniProtKB:Q70T00 xref: UniProtKB:Q70T01 xref: UniProtKB:Q70T02 xref: UniProtKB:Q70T03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005726 ! TAF1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:I0006023 ! taf1-gtf2f1-3 physical interaction relationship: participates_in CCO:I0006196 ! rb1-taf1-1 physical interaction relationship: participates_in CCO:I0006199 ! taf1-gtf2f1-1 physical interaction relationship: participates_in CCO:I0006200 ! taf1-gtf2f1-2 physical interaction relationship: participates_in CCO:I0006298 ! tbp-taf1-2 physical interaction relationship: participates_in CCO:I0006714 ! tbp-taf1-1 physical interaction relationship: participates_in CCO:I0006939 ! brms1-taf1 physical interaction relationship: participates_in CCO:I0007678 ! gfi1b-taf1 physical interaction relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014305 ! TAF1_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0014306 ! TAF1_HUMAN-Phosphoserine307 [Term] id: CCO:B0001544 name: MK_HUMAN def: "Midkine precursor" [UniProtKB:P21741] synonym: "Amphiregulin-associated protein" EXACT [UniProtKB:P21741] synonym: "ARAP" EXACT [UniProtKB:P21741] synonym: "Midgestation and kidney protein" EXACT [UniProtKB:P21741] synonym: "MK" EXACT [UniProtKB:P21741] synonym: "Neurite outgrowth-promoting factor 2" EXACT [UniProtKB:P21741] synonym: "Neurite outgrowth-promoting protein" EXACT [UniProtKB:P21741] xref: EMBL:AAA58478.1 xref: EMBL:AAA59850.1 xref: EMBL:AAH11704.1 xref: EMBL:BAA01457.1 xref: EMBL:CAA38908.1 xref: UniProtKB:P21741 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005098 ! MDK_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0006641 ! mdk-ubqln4 physical interaction relationship: participates_in CCO:I0007609 ! ubqln4-mdk physical interaction relationship: participates_in CCO:I0008431 ! rpl18a-mdk physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001545 name: FGF7_HUMAN def: "Keratinocyte growth factor precursor" [UniProtKB:P21781] synonym: "FGF-7" EXACT [UniProtKB:P21781] synonym: "Fibroblast growth factor 7" EXACT [UniProtKB:P21781] synonym: "HBGF-7" EXACT [UniProtKB:P21781] synonym: "Heparin-binding growth factor 7" EXACT [UniProtKB:P21781] synonym: "KGF" EXACT [UniProtKB:P21781] xref: EMBL:AAA63210.1 xref: EMBL:AAB21431.1 xref: UniProtKB:P21781 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004638 ! FGF7_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0001546 name: NDKB_HUMAN def: "Nucleoside diphosphate kinase B" [UniProtKB:P22392] synonym: "C-myc purine-binding transcription factor PUF" EXACT [UniProtKB:P22392] synonym: "EC 2.7.4.6" EXACT [UniProtKB:P22392] synonym: "NDK B" EXACT [UniProtKB:P22392] synonym: "NDP kinase B" EXACT [UniProtKB:P22392] synonym: "nm23-H2" EXACT [UniProtKB:P22392] xref: EMBL:AAA36369.1 xref: EMBL:AAA60228.1 xref: EMBL:AAH02476.1 xref: EMBL:CAB37870.1 xref: UniProtKB:P22392 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005168 ! NME2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000936 ! nucleoside diphosphate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:I0008137 ! nme3-nme2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002432 ! positive regulation of keratinocyte differentiation relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0001548 name: TBG1_HUMAN def: "Tubulin gamma-1 chain" [UniProtKB:P23258] synonym: "Gamma-1-tubulin" EXACT [UniProtKB:P23258] synonym: "Gamma-tubulin complex component 1" EXACT [UniProtKB:P23258] synonym: "GCP-1" EXACT [UniProtKB:P23258] xref: EMBL:AAA52620.1 xref: EMBL:AAH00619.1 xref: EMBL:AAV38734.1 xref: UniProtKB:P23258 xref: UniProtKB:Q9BW59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005740 ! TUBG1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000043 ! pericentriolar material relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000149 ! gamma-tubulin complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000386 ! spindle pole body relationship: located_in CCO:C0000395 ! polar microtubule relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000439 ! cytoplasmic microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0006006 ! tubg-mark4-2 physical interaction relationship: participates_in CCO:I0006007 ! tubg-mark4-3 physical interaction relationship: participates_in CCO:I0006723 ! disc1-tubg colocalization relationship: participates_in CCO:I0007067 ! tubg-mark4-1 physical interaction relationship: participates_in CCO:I0007970 ! disc1-tubg-1 physical interaction relationship: participates_in CCO:P0000030 ! meiotic spindle organization and biogenesis [Term] id: CCO:B0001549 name: CRCM_HUMAN def: "Colorectal mutant cancer protein" [UniProtKB:P23508] synonym: "Protein MCC" EXACT [UniProtKB:P23508] xref: EMBL:AAA52069.1 xref: EMBL:AAH09279.1 xref: EMBL:AAH18919.1 xref: UniProtKB:P23508 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004394 ! MCC_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006375 ! map3k3-mcc physical interaction relationship: participates_in CCO:I0006426 ! nfkbib-mcc physical interaction relationship: participates_in CCO:I0007400 ! mcc-nfkbib physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0001550 name: KTHY_HUMAN def: "Thymidylate kinase" [UniProtKB:P23919] synonym: "dTMP kinase" EXACT [UniProtKB:P23919] synonym: "EC 2.7.4.9" EXACT [UniProtKB:P23919] xref: EMBL:AAA21719.1 xref: EMBL:AAH01827.1 xref: EMBL:CAA38528.1 xref: EMBL:CAG46783.1 xref: UniProtKB:P23919 xref: UniProtKB:Q6FGX1 xref: UniProtKB:Q9BUX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004518 ! DTYMK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001156 ! thymidylate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004129 ! nucleoside kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001551 name: CCND1_HUMAN def: "G1/S-specific cyclin-D1" [UniProtKB:P24385] synonym: "BCL-1 oncogene" EXACT [UniProtKB:P24385] synonym: "PRAD1 oncogene" EXACT [UniProtKB:P24385] xref: EMBL:AAA36481.1 xref: EMBL:AAA52136.1 xref: EMBL:AAA58392.1 xref: EMBL:AAH00076.1 xref: EMBL:AAH01501.1 xref: EMBL:AAH14078.1 xref: EMBL:AAH23620.1 xref: EMBL:AAH25302.1 xref: EMBL:AAM34300.2 xref: EMBL:AAV38648.1 xref: EMBL:CAA42470.1 xref: EMBL:CAA80558.1 xref: UniProtKB:P24385 xref: UniProtKB:Q6LEF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004248 ! CCND1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006091 ! orc4l-ccnd1 direct interaction relationship: participates_in CCO:I0006105 ! mcm10-ccnd1 direct interaction relationship: participates_in CCO:I0006134 ! cdk4-ccnd1 direct interaction relationship: participates_in CCO:I0006140 ! cdkn1a-ccnd1 direct interaction relationship: participates_in CCO:I0006143 ! cdk6-ccnd1 direct interaction relationship: participates_in CCO:I0006827 ! ccnd1-cdkn1b-2 physical interaction relationship: participates_in CCO:I0006862 ! cdk4-ccnd1-5 physical interaction relationship: participates_in CCO:I0007090 ! cdk4-ccnd1-3 physical interaction relationship: participates_in CCO:I0007091 ! cdkn1a-ccnd1-1 physical interaction relationship: participates_in CCO:I0007092 ! cdkn1b-ccnd1-2 physical interaction relationship: participates_in CCO:I0007248 ! cdk4-ccnd1-6 physical interaction relationship: participates_in CCO:I0007544 ! cdk4-ccnd1-1 physical interaction relationship: participates_in CCO:I0007545 ! cdk4-ccnd1-2 physical interaction relationship: participates_in CCO:I0007739 ! cdk4-ccnd1-4 physical interaction relationship: participates_in CCO:I0007854 ! cdkn1a-ccnd1-2 physical interaction relationship: participates_in CCO:I0007902 ! cyclind1_cdk4_human direct interaction relationship: participates_in CCO:I0007906 ! cyclind1_cdk6_human direct interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000041 ! re-entry into mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000243 ! positive regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0048182 ! CCND1_HUMAN-Phosphotyrosine226 [Term] id: CCO:B0001552 name: GA45A_HUMAN def: "Growth arrest and DNA-damage-inducible protein GADD45 alpha" [UniProtKB:P24522] synonym: "DDIT-1" EXACT [UniProtKB:P24522] synonym: "DNA-damage-inducible transcript 1" EXACT [UniProtKB:P24522] xref: EMBL:AAA35863.1 xref: EMBL:AAA72045.1 xref: EMBL:AAH11757.1 xref: EMBL:AAM88884.1 xref: UniProtKB:P24522 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004674 ! GADD45A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005729 ! dctn2-gadd45a physical interaction relationship: participates_in CCO:I0007530 ! map3k4-gadd45 physical interaction relationship: participates_in CCO:I0008475 ! ftl-gadd45a physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001553 name: CCNC_HUMAN def: "Cyclin-C" [UniProtKB:P24863] synonym: "hSRB11" EXACT [UniProtKB:P24863] xref: EMBL:AAC50825.1 xref: EMBL:CAC14563.1 xref: UniProtKB:P24863 xref: UniProtKB:Q9H543 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004247 ! CCNC_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0031301 ! CCNC_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0031302 ! CCNC_HUMAN-Phosphotyrosine122 relationship: transforms_into CCO:B0031303 ! CCNC_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0031304 ! CCNC_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0031305 ! CCNC_HUMAN-Phosphoserine281 [Term] id: CCO:B0001554 name: CCNE1_HUMAN def: "G1/S-specific cyclin-E1" [UniProtKB:P24864] xref: EMBL:AAA83269.1 xref: EMBL:AAH35498.1 xref: EMBL:AAM54043.1 xref: EMBL:CAA64687.1 xref: EMBL:CAA64688.1 xref: UniProtKB:P24864 xref: UniProtKB:Q14091 xref: UniProtKB:Q8NFG1 xref: UniProtKB:Q92501 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004251 ! CCNE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005984 ! cdn1b-cdk2-1 physical interaction relationship: participates_in CCO:I0005985 ! cdn1b-cdk2-2 physical interaction relationship: participates_in CCO:I0006201 ! ccne1-nbs1-1 physical interaction relationship: participates_in CCO:I0006202 ! ccne1-mre11a-1 physical interaction relationship: participates_in CCO:I0006290 ! cdkn1a-ccne1-2 physical interaction relationship: participates_in CCO:I0006291 ! cdkn1b-ccne1-1 physical interaction relationship: participates_in CCO:I0006293 ! cdkn1a-ccne1-3 physical interaction relationship: participates_in CCO:I0006295 ! cdk2-ccne1-1 physical interaction relationship: participates_in CCO:I0006297 ! cdkn1a-ccne1-4 physical interaction relationship: participates_in CCO:I0006552 ! cdk2-pin1-3 physical interaction relationship: participates_in CCO:I0006553 ! cdk2-ccne1-3 physical interaction relationship: participates_in CCO:I0006826 ! ccne1-cdkn1b-1 physical interaction relationship: participates_in CCO:I0007247 ! cdk2-ccne1-2 physical interaction relationship: participates_in CCO:I0007349 ! cdkn1a-ccne1-5 physical interaction relationship: participates_in CCO:I0007481 ! cdn1b-cdk2-3 physical interaction relationship: participates_in CCO:I0007484 ! cdn1b-cdk2-4 physical interaction relationship: participates_in CCO:I0007485 ! cdn1b-cdk2-5 physical interaction relationship: participates_in CCO:I0007853 ! cdkn1a-ccne1-6 physical interaction relationship: participates_in CCO:I0007856 ! cdkn1a-ccne1-7 physical interaction relationship: participates_in CCO:I0007907 ! cycline1_cdk2_human direct interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010992 ! CCNE1_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0010993 ! CCNE1_HUMAN-Phosphothreonine77 relationship: transforms_into CCO:B0010994 ! CCNE1_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0010995 ! CCNE1_HUMAN-Phosphothreonine395 relationship: transforms_into CCO:B0010996 ! CCNE1_HUMAN-Phosphoserine399 [Term] id: CCO:B0001555 name: CDK2_HUMAN def: "Cell division protein kinase 2" [UniProtKB:P24941] synonym: "EC 2.7.11.22" EXACT [UniProtKB:P24941] synonym: "p33 protein kinase" EXACT [UniProtKB:P24941] xref: EMBL:AAA35667.1 xref: EMBL:AAH03065.1 xref: EMBL:AAM34794.1 xref: EMBL:AAP35467.1 xref: EMBL:CAA43807.1 xref: EMBL:CAA43985.1 xref: UniProtKB:P24941 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004299 ! CDK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005984 ! cdn1b-cdk2-1 physical interaction relationship: participates_in CCO:I0005985 ! cdn1b-cdk2-2 physical interaction relationship: participates_in CCO:I0006020 ! orc1-cdk2-1 physical interaction relationship: participates_in CCO:I0006027 ! uhrf2-cdk2-1 physical interaction relationship: participates_in CCO:I0006028 ! uhrf2-cdk2-3 physical interaction relationship: participates_in CCO:I0006059 ! cdknib-cdk2 physical interaction relationship: participates_in CCO:I0006127 ! cdk2-ccne2 direct interaction relationship: participates_in CCO:I0006150 ! orc2l-cdk2 direct interaction relationship: participates_in CCO:I0006155 ! cdk2-ccnb2 direct interaction relationship: participates_in CCO:I0006158 ! mcm3-cdk2 direct interaction relationship: participates_in CCO:I0006159 ! cdkn1a-cdk2 direct interaction relationship: participates_in CCO:I0006294 ! cdkn1a-cdk2-1 physical interaction relationship: participates_in CCO:I0006295 ! cdk2-ccne1-1 physical interaction relationship: participates_in CCO:I0006332 ! ccna2_cdk2-1 direct interaction relationship: participates_in CCO:I0006451 ! ccna2-cdk2-10 direct interaction relationship: participates_in CCO:I0006452 ! ccna2-cdk2-11 direct interaction relationship: participates_in CCO:I0006552 ! cdk2-pin1-3 physical interaction relationship: participates_in CCO:I0006553 ! cdk2-ccne1-3 physical interaction relationship: participates_in CCO:I0006563 ! ccna2-cdk2-2 direct interaction relationship: participates_in CCO:I0006566 ! cdk2-cdkn3-1 direct interaction relationship: participates_in CCO:I0006770 ! ccna2-cdk2-3 direct interaction relationship: participates_in CCO:I0006798 ! ccna2-cdk2-8 direct interaction relationship: participates_in CCO:I0006945 ! cdkn1b-abl-2 phosphorylation relationship: participates_in CCO:I0007057 ! cdkn1b-cdk2-2 physical interaction relationship: participates_in CCO:I0007058 ! cdkn1b-cdk2-3 direct interaction relationship: participates_in CCO:I0007120 ! uhrf2-cdk2-4 direct interaction relationship: participates_in CCO:I0007247 ! cdk2-ccne1-2 physical interaction relationship: participates_in CCO:I0007323 ! cdkn1b-cdk2-4 physical interaction relationship: participates_in CCO:I0007350 ! cdk2-rb1-1 phosphorylation relationship: participates_in CCO:I0007351 ! cdk2-rb1-2 phosphorylation relationship: participates_in CCO:I0007419 ! uhrf2-cdk2-2 physical interaction relationship: participates_in CCO:I0007481 ! cdn1b-cdk2-3 physical interaction relationship: participates_in CCO:I0007484 ! cdn1b-cdk2-4 physical interaction relationship: participates_in CCO:I0007485 ! cdn1b-cdk2-5 physical interaction relationship: participates_in CCO:I0007487 ! cdkn1b-cdk2-1 physical interaction relationship: participates_in CCO:I0007488 ! cdkn1b-cdk2-5 phosphorylation relationship: participates_in CCO:I0007499 ! ccna2-cdk2-4 direct interaction relationship: participates_in CCO:I0007500 ! ccna2-cdk2-5 direct interaction relationship: participates_in CCO:I0007501 ! ccna2-cdk2-6 direct interaction relationship: participates_in CCO:I0007502 ! ccna2-cdk2-7 direct interaction relationship: participates_in CCO:I0007533 ! cdt1-cdk2-1 physical interaction relationship: participates_in CCO:I0007825 ! ccna2-cdk2-1 physical interaction relationship: participates_in CCO:I0007853 ! cdkn1a-ccne1-6 physical interaction relationship: participates_in CCO:I0007855 ! cdkn1a-ccna1-1 physical interaction relationship: participates_in CCO:I0007857 ! cdkn1a-cdk2-2 physical interaction relationship: participates_in CCO:I0007897 ! cyclina1_cdk2_human direct interaction relationship: participates_in CCO:I0007898 ! cyclina2_cdk2_human direct interaction relationship: participates_in CCO:I0007901 ! cyclinb3_cdk2_human direct interaction relationship: participates_in CCO:I0007907 ! cycline1_cdk2_human direct interaction relationship: participates_in CCO:I0007908 ! cycline2_cdk2_human direct interaction relationship: participates_in CCO:I0007941 ! ccna2-cdk2-9 direct interaction relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000100 ! traversing start control point of mitotic cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000639 ! regulation of DNA replication relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011103 ! CDK2_HUMAN-Phosphothreonine14 relationship: transforms_into CCO:B0011104 ! CDK2_HUMAN-Phosphotyrosine15 relationship: transforms_into CCO:B0011105 ! CDK2_HUMAN-Phosphotyrosine19 relationship: transforms_into CCO:B0011106 ! CDK2_HUMAN-Phosphothreonine160 [Term] id: CCO:B0001556 name: APC_HUMAN def: "Adenomatous polyposis coli protein" [UniProtKB:P25054] synonym: "Deleted in polyposis 2.5" EXACT [UniProtKB:P25054] synonym: "Protein APC" EXACT [UniProtKB:P25054] xref: EMBL:AAA03586.1 xref: EMBL:AAA60353.1 xref: EMBL:AAA60354.1 xref: EMBL:AAB21145.2 xref: UniProtKB:P25054 xref: UniProtKB:Q15162 xref: UniProtKB:Q15163 xref: UniProtKB:Q93042 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004081 ! APC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006260 ! csnk1e-apc phosphorylation relationship: participates_in CCO:I0006540 ! apc-ctbb1-1 physical interaction relationship: participates_in CCO:I0007024 ! apc-ctnnb1-3 direct interaction relationship: participates_in CCO:I0007447 ! apc-ctbb1 physical interaction relationship: participates_in CCO:I0007457 ! eb1-apc-1 physical interaction relationship: participates_in CCO:I0007942 ! apc-ctnnb1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0003180 ! regulation of attachment of spindle microtubules to kinetochore relationship: participates_in CCO:P0003241 ! Wnt receptor signaling pathway through beta-catenin relationship: transforms_into CCO:B0010567 ! APC_HUMAN-Phosphoserine1038 relationship: transforms_into CCO:B0010568 ! APC_HUMAN-Phosphoserine1180 relationship: transforms_into CCO:B0010569 ! APC_HUMAN-Phosphoserine1371 relationship: transforms_into CCO:B0010570 ! APC_HUMAN-Phosphothreonine1697 relationship: transforms_into CCO:B0010571 ! APC_HUMAN-Phosphoserine1861 relationship: transforms_into CCO:B0010572 ! APC_HUMAN-Phosphoserine1863 relationship: transforms_into CCO:B0010573 ! APC_HUMAN-Phosphoserine1864 relationship: transforms_into CCO:B0010574 ! APC_HUMAN-Phosphoserine2283 relationship: transforms_into CCO:B0010575 ! APC_HUMAN-Phosphoserine2398 relationship: transforms_into CCO:B0010576 ! APC_HUMAN-Phosphoserine2674 relationship: transforms_into CCO:B0010577 ! APC_HUMAN-Phosphoserine2710 relationship: transforms_into CCO:B0048164 ! APC_HUMAN-Phosphoserine2125 relationship: transforms_into CCO:B0048165 ! APC_HUMAN-Phosphoserine2671 relationship: transforms_into CCO:B0048166 ! APC_HUMAN-Phosphothreonine2676 relationship: transforms_into CCO:B0048167 ! APC_HUMAN-Phosphoserine2789 relationship: transforms_into CCO:B0048168 ! APC_HUMAN-Phosphoserine2835 relationship: transforms_into CCO:B0048169 ! APC_HUMAN-Phosphoserine2837 relationship: transforms_into CCO:B0048170 ! APC_HUMAN-Phosphotyrosine2838 [Term] id: CCO:B0001557 name: PAR1_HUMAN def: "Proteinase-activated receptor 1 precursor" [UniProtKB:P25116] synonym: "Coagulation factor II receptor" EXACT [UniProtKB:P25116] synonym: "PAR-1" EXACT [UniProtKB:P25116] synonym: "Thrombin receptor" EXACT [UniProtKB:P25116] xref: EMBL:AAA36743.1 xref: EMBL:AAH02464.1 xref: EMBL:AAH51909.1 xref: EMBL:AAK69768.1 xref: UniProtKB:P25116 xref: UniProtKB:Q96RF7 xref: UniProtKB:Q9BUN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005260 ! F2R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002550 ! thrombin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001131 ! platelet dense tubular network relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000777 ! tyrosine phosphorylation of STAT protein relationship: participates_in CCO:P0000779 ! STAT protein nuclear translocation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0001742 ! positive regulation of collagen biosynthetic process relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002178 ! positive regulation of caspase activity relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002694 ! positive regulation of JAK-STAT cascade [Term] id: CCO:B0001558 name: MCM3_HUMAN def: "DNA replication licensing factor MCM3" [UniProtKB:P25205] synonym: "DNA polymerase alpha holoenzyme-associated protein P1" EXACT [UniProtKB:P25205] synonym: "P1-MCM3" EXACT [UniProtKB:P25205] synonym: "P102 protein" EXACT [UniProtKB:P25205] synonym: "RLF subunit beta" EXACT [UniProtKB:P25205] xref: EMBL:AAH01626.1 xref: EMBL:AAH03509.2 xref: EMBL:AAT27321.1 xref: EMBL:BAA07267.1 xref: EMBL:CAA44078.2 xref: EMBL:CAB75298.1 xref: UniProtKB:P25205 xref: UniProtKB:Q92660 xref: UniProtKB:Q9BTR3 xref: UniProtKB:Q9NUE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005038 ! MCM3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006078 ! mcm2-mcm3 direct interaction relationship: participates_in CCO:I0006080 ! mcm5-mcm3 direct interaction relationship: participates_in CCO:I0006093 ! mcm3-orc5l direct interaction relationship: participates_in CCO:I0006094 ! mcm3-hscdc5 direct interaction relationship: participates_in CCO:I0006095 ! mcm10-mcm3 direct interaction relationship: participates_in CCO:I0006096 ! orc4l-mcm3 direct interaction relationship: participates_in CCO:I0006146 ! mcm3-cdc7 direct interaction relationship: participates_in CCO:I0006154 ! mcm3-hscdc6 direct interaction relationship: participates_in CCO:I0006158 ! mcm3-cdk2 direct interaction relationship: participates_in CCO:I0006163 ! mcm3-mcm6 direct interaction relationship: participates_in CCO:I0006355 ! nfkbia-mcm3 physical interaction relationship: participates_in CCO:I0006956 ! plk1-mcm3-1 physical interaction relationship: participates_in CCO:I0007539 ! orc2-mcm3-1 physical interaction relationship: participates_in CCO:I0007540 ! mcm3-mcm5-1 physical interaction relationship: participates_in CCO:I0007541 ! mcm3-mcm5-2 physical interaction relationship: participates_in CCO:I0007914 ! mcm2-7_human physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012814 ! MCM3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0012815 ! MCM3_HUMAN-Phosphoserine535 relationship: transforms_into CCO:B0012816 ! MCM3_HUMAN-Phosphoserine668 relationship: transforms_into CCO:B0012817 ! MCM3_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0012818 ! MCM3_HUMAN-Phosphothreonine674 relationship: transforms_into CCO:B0012819 ! MCM3_HUMAN-Phosphoserine681 relationship: transforms_into CCO:B0012820 ! MCM3_HUMAN-Phosphoserine704 relationship: transforms_into CCO:B0012821 ! MCM3_HUMAN-Phosphoserine711 relationship: transforms_into CCO:B0012822 ! MCM3_HUMAN-Phosphothreonine713 relationship: transforms_into CCO:B0012823 ! MCM3_HUMAN-Phosphothreonine722 relationship: transforms_into CCO:B0012824 ! MCM3_HUMAN-Phosphoserine728 relationship: transforms_into CCO:B0012825 ! MCM3_HUMAN-Phosphoserine734 [Term] id: CCO:B0001559 name: 1433T_HUMAN def: "14-3-3 protein theta" [UniProtKB:P27348] synonym: "14-3-3 protein T-cell" EXACT [UniProtKB:P27348] synonym: "14-3-3 protein tau" EXACT [UniProtKB:P27348] synonym: "Protein HS1" EXACT [UniProtKB:P27348] xref: EMBL:AAC28640.1 xref: EMBL:AAH01197.1 xref: EMBL:AAH50601.1 xref: EMBL:AAH56867.1 xref: EMBL:AAH93019.1 xref: EMBL:AAV38817.1 xref: EMBL:CAA39840.1 xref: EMBL:CAA40622.1 xref: UniProtKB:P27348 xref: UniProtKB:Q567U5 xref: UniProtKB:Q5TZU8 xref: UniProtKB:Q9UP48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003997 ! YWHAQ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006336 ! fshr-ywhaq-3 physical interaction relationship: participates_in CCO:I0006435 ! map3k3-ywhaq physical interaction relationship: participates_in CCO:I0006512 ! map3k5-ywhaq-1 physical interaction relationship: participates_in CCO:I0006804 ! disc1-ywhaq physical interaction relationship: participates_in CCO:I0006884 ! fshr-ywhaq-1 physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007288 ! fshr-ywhaq-2 physical interaction relationship: participates_in CCO:I0007612 ! ubqln4-ywhaq physical interaction relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0041106 ! 1433T_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0001560 name: MK03_HUMAN def: "Mitogen-activated protein kinase 3" [UniProtKB:P27361] synonym: "EC 2.7.11.24" EXACT [UniProtKB:P27361] synonym: "ERK-1" EXACT [UniProtKB:P27361] synonym: "ERT2" EXACT [UniProtKB:P27361] synonym: "Extracellular signal-regulated kinase 1" EXACT [UniProtKB:P27361] synonym: "Insulin-stimulated MAP2 kinase" EXACT [UniProtKB:P27361] synonym: "MAP kinase 1" EXACT [UniProtKB:P27361] synonym: "MAPK 1" EXACT [UniProtKB:P27361] synonym: "Microtubule-associated protein 2 kinase" EXACT [UniProtKB:P27361] synonym: "p44-ERK1" EXACT [UniProtKB:P27361] synonym: "p44-MAPK" EXACT [UniProtKB:P27361] xref: EMBL:AAA36142.1 xref: EMBL:AAH13992.1 xref: EMBL:CAA42744.1 xref: EMBL:CAA77754.1 xref: UniProtKB:P27361 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005090 ! MAPK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006299 ! dapk-erk physical interaction relationship: participates_in CCO:I0006300 ! dapk-erk-3 physical interaction relationship: participates_in CCO:I0006672 ! rps6ka4-mapk3 physical interaction relationship: participates_in CCO:I0006717 ! mapk3-elk1-1 phosphorylation relationship: participates_in CCO:I0007551 ! dapk-erk-2 physical interaction relationship: participates_in CCO:I0007858 ! dapk-erk-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0012941 ! MK03_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0012942 ! MK03_HUMAN-Phosphothreonine202 relationship: transforms_into CCO:B0012943 ! MK03_HUMAN-Phosphotyrosine204 [Term] id: CCO:B0001561 name: G0S2_HUMAN def: "Putative lymphocyte G0/G1 switch protein 2" [UniProtKB:P27469] xref: EMBL:AAA58966.1 xref: EMBL:AAB04044.1 xref: EMBL:AAH09694.1 xref: EMBL:CAB40150.1 xref: UniProtKB:P27469 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004668 ! G0S2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001562 name: RFA1_HUMAN def: "Replication protein A 70 kDa DNA-binding subunit" [UniProtKB:P27694] synonym: "Replication factor A protein 1" EXACT [UniProtKB:P27694] synonym: "RF-A protein 1" EXACT [UniProtKB:P27694] synonym: "RP-A p70" EXACT [UniProtKB:P27694] synonym: "Single-stranded DNA-binding protein" EXACT [UniProtKB:P27694] xref: EMBL:AAA36584.1 xref: EMBL:AAH18126.1 xref: EMBL:AAS94324.1 xref: EMBL:BAD92969.1 xref: UniProtKB:P27694 xref: UniProtKB:Q59ES9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005469 ! RPA1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000267 ! DNA replication factor A complex relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:I0006325 ! rpa1-rpa2-1 direct interaction relationship: participates_in CCO:I0006734 ! wrn-rpa1-2 physical interaction relationship: participates_in CCO:I0006735 ! wrn-rpa1-3 physical interaction relationship: participates_in CCO:I0006736 ! wrn-rpa1-4 physical interaction relationship: participates_in CCO:I0007281 ! wrn-rpa70-1 physical interaction relationship: participates_in CCO:I0007282 ! rpa1-rpa2-2 physical interaction relationship: participates_in CCO:I0007498 ! rpa1-rpa2-3 physical interaction relationship: participates_in CCO:I0007580 ! wrn-rpa1-7 physical interaction relationship: participates_in CCO:I0007581 ! p53-rpa1-8 physical interaction relationship: participates_in CCO:I0007748 ! c9orf76-blm-1 physical interaction relationship: participates_in CCO:I0007749 ! blm-c9orf76-1 physical interaction relationship: participates_in CCO:I0007759 ! wrn-rpa1-1 physical interaction relationship: participates_in CCO:I0007760 ! wrn-rpa1-5 physical interaction relationship: participates_in CCO:I0007761 ! wrn-rpa1-6 physical interaction relationship: participates_in CCO:I0007762 ! blm-rpa1-1 physical interaction relationship: participates_in CCO:I0007763 ! blm-rpa1-2 physical interaction relationship: participates_in CCO:I0007996 ! ascc2-rpa1 physical interaction relationship: participates_in CCO:I0008009 ! cpe-rpa1 physical interaction relationship: participates_in CCO:I0008012 ! fts-rpa1 physical interaction relationship: participates_in CCO:I0008020 ! loc51236-rpa1 physical interaction relationship: participates_in CCO:I0008044 ! rnpc4-rpa1 physical interaction relationship: participates_in CCO:I0008049 ! selenbp1-rpa1 physical interaction relationship: participates_in CCO:I0008436 ! tcea2-rpa1 physical interaction relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: transforms_into CCO:B0013822 ! RFA1_HUMAN-Phosphothreonine180 [Term] id: CCO:B0001563 name: CALR_HUMAN def: "Calreticulin precursor" [UniProtKB:P27797] synonym: "Calregulin" EXACT [UniProtKB:P27797] synonym: "CRP55" EXACT [UniProtKB:P27797] synonym: "ERp60" EXACT [UniProtKB:P27797] synonym: "grp60" EXACT [UniProtKB:P27797] synonym: "HACBP" EXACT [UniProtKB:P27797] xref: EMBL:AAA36582.1 xref: EMBL:AAA51916.1 xref: EMBL:AAB51176.1 xref: EMBL:AAH02500.1 xref: EMBL:AAH07911.1 xref: EMBL:AAH20493.1 xref: EMBL:AAL13126.1 xref: UniProtKB:P27797 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004217 ! CALR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007317 ! tap1-calr direct interaction relationship: participates_in CCO:I0007710 ! tap1-b2m physical interaction relationship: participates_in CCO:P0000226 ! regulation of meiosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0001564 name: DPOD1_HUMAN def: "DNA polymerase delta catalytic subunit" [UniProtKB:P28340] synonym: "DNA polymerase subunit delta p125" EXACT [UniProtKB:P28340] synonym: "EC 2.7.7.7" EXACT [UniProtKB:P28340] xref: EMBL:AAA35768.1 xref: EMBL:AAA58439.1 xref: EMBL:AAH08800.1 xref: EMBL:AAM76971.1 xref: UniProtKB:P28340 xref: UniProtKB:Q8NER3 xref: UniProtKB:Q96H98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004501 ! POLD1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0005986 ! pcna-pold1-1 physical interaction relationship: participates_in CCO:I0007289 ! pold1-pold2-4 physical interaction relationship: participates_in CCO:I0007290 ! pold1-pold2-5 physical interaction relationship: participates_in CCO:I0007588 ! pold1-pold2-1 physical interaction relationship: participates_in CCO:I0007589 ! pold1-pold2-3 physical interaction relationship: participates_in CCO:I0007590 ! pold1-pold4-1 direct interaction relationship: participates_in CCO:I0007910 ! pold1-pold2-6 physical interaction relationship: participates_in CCO:I0007911 ! pold1-pold2-7 physical interaction relationship: participates_in CCO:I0007912 ! dpol-delta_human physical interaction relationship: participates_in CCO:I0007968 ! pold1pold2-8 physical interaction relationship: participates_in CCO:I0008295 ! pold1-chgb physical interaction relationship: participates_in CCO:I0008296 ! pold1-kiaa1377 physical interaction relationship: participates_in CCO:P0000014 ! S phase of mitotic cell cycle relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0001565 name: MK01_HUMAN def: "Mitogen-activated protein kinase 1" [UniProtKB:P28482] synonym: "EC 2.7.11.24" EXACT [UniProtKB:P28482] synonym: "ERK-2" EXACT [UniProtKB:P28482] synonym: "ERT1" EXACT [UniProtKB:P28482] synonym: "Extracellular signal-regulated kinase 2" EXACT [UniProtKB:P28482] synonym: "MAP kinase 2" EXACT [UniProtKB:P28482] synonym: "MAPK 2" EXACT [UniProtKB:P28482] synonym: "Mitogen-activated protein kinase 2" EXACT [UniProtKB:P28482] synonym: "p42-MAPK" EXACT [UniProtKB:P28482] xref: EMBL:AAA58459.1 xref: EMBL:AAH17832.1 xref: EMBL:CAA77752.1 xref: EMBL:CAA77753.1 xref: UniProtKB:P28482 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005089 ! MAPK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000213 ! phosphotyrosine binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006556 ! mapk1-dusp1-1 physical interaction relationship: participates_in CCO:I0006557 ! mapk1-dusp1-2 physical interaction relationship: participates_in CCO:I0006718 ! mapk1-elk1-1 phosphorylation relationship: participates_in CCO:I0006901 ! mapk1-dusp1-3 phosphorylation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0001484 ! lipopolysaccharide-mediated signaling pathway relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: transforms_into CCO:B0012937 ! MK01_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0012938 ! MK01_HUMAN-Phosphothreonine185 relationship: transforms_into CCO:B0012939 ! MK01_HUMAN-Phosphotyrosine187 relationship: transforms_into CCO:B0012940 ! MK01_HUMAN-Phosphothreonine190 [Term] id: CCO:B0001566 name: DUS1_HUMAN def: "Dual specificity protein phosphatase 1" [UniProtKB:P28562] synonym: "Dual specificity protein phosphatase hVH1" EXACT [UniProtKB:P28562] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P28562] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P28562] synonym: "MAP kinase phosphatase 1" EXACT [UniProtKB:P28562] synonym: "MKP-1" EXACT [UniProtKB:P28562] synonym: "Protein-tyrosine phosphatase CL100" EXACT [UniProtKB:P28562] xref: EMBL:AAH22463.1 xref: EMBL:ABB96250.1 xref: EMBL:CAA48338.1 xref: UniProtKB:P28562 xref: UniProtKB:Q2V508 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004521 ! DUSP1_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001091 ! non-membrane spanning protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006556 ! mapk1-dusp1-1 physical interaction relationship: participates_in CCO:I0006557 ! mapk1-dusp1-2 physical interaction relationship: participates_in CCO:I0006745 ! dusp1-ubiq-1 ubiquitination relationship: participates_in CCO:I0006746 ! dusp1-skp2-1 physical interaction relationship: participates_in CCO:I0006747 ! dusp1-skp2-2 physical interaction relationship: participates_in CCO:I0006901 ! mapk1-dusp1-3 phosphorylation relationship: participates_in CCO:I0007149 ! dusp1-skp2-3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0001567 name: RBL1_HUMAN def: "Retinoblastoma-like protein 1" [UniProtKB:P28749] synonym: "107 kDa retinoblastoma-associated protein" EXACT [UniProtKB:P28749] synonym: "p107" EXACT [UniProtKB:P28749] synonym: "PRB1" EXACT [UniProtKB:P28749] xref: EMBL:AAA02489.1 xref: EMBL:AAA36397.1 xref: EMBL:AAD14290.1 xref: EMBL:AAH32247.1 xref: EMBL:CAI95151.1 xref: EMBL:CAI95152.1 xref: EMBL:CAI95177.1 xref: EMBL:CAI95178.1 xref: EMBL:CAI95716.1 xref: EMBL:CAI95717.1 xref: UniProtKB:P28749 xref: UniProtKB:Q4VXA0 xref: UniProtKB:Q8N5K6 xref: UniProtKB:Q9H1L5 xref: UniProtKB:Q9H1M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005445 ! RBL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013754 ! RBL1_HUMAN-Phosphothreonine332 relationship: transforms_into CCO:B0013755 ! RBL1_HUMAN-Phosphothreonine369 relationship: transforms_into CCO:B0013756 ! RBL1_HUMAN-Phosphothreonine385 relationship: transforms_into CCO:B0013757 ! RBL1_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0013758 ! RBL1_HUMAN-Phosphoserine650 relationship: transforms_into CCO:B0013759 ! RBL1_HUMAN-Phosphoserine762 relationship: transforms_into CCO:B0013760 ! RBL1_HUMAN-Phosphoserine964 relationship: transforms_into CCO:B0013761 ! RBL1_HUMAN-Phosphoserine975 relationship: transforms_into CCO:B0013762 ! RBL1_HUMAN-Phosphoserine988 relationship: transforms_into CCO:B0013763 ! RBL1_HUMAN-Phosphothreonine997 relationship: transforms_into CCO:B0013764 ! RBL1_HUMAN-Phosphoserine1009 [Term] id: CCO:B0001568 name: EPHB2_HUMAN def: "Ephrin type-B receptor 2 precursor" [UniProtKB:P29323] synonym: "DRT" EXACT [UniProtKB:P29323] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P29323] synonym: "ERK" EXACT [UniProtKB:P29323] synonym: "Receptor protein-tyrosine kinase HEK5" EXACT [UniProtKB:P29323] synonym: "Renal carcinoma antigen NY-REN-47" EXACT [UniProtKB:P29323] synonym: "Tyrosine-protein kinase receptor EPH-3" EXACT [UniProtKB:P29323] synonym: "Tyrosine-protein kinase TYRO5" EXACT [UniProtKB:P29323] xref: EMBL:AAA74244.1 xref: EMBL:AAA99310.1 xref: EMBL:AAB94602.1 xref: EMBL:BAA03537.1 xref: EMBL:BAA06506.1 xref: EMBL:BAA07073.1 xref: EMBL:CAA41981.1 xref: EMBL:CAI16428.1 xref: EMBL:CAI16429.1 xref: EMBL:CAI16430.2 xref: EMBL:CAI22645.1 xref: EMBL:CAI22646.1 xref: EMBL:CAI22647.2 xref: EMBL:CAI22897.1 xref: EMBL:CAI22898.1 xref: EMBL:CAI22899.2 xref: UniProtKB:O43477 xref: UniProtKB:P29323 xref: UniProtKB:Q5T0U6 xref: UniProtKB:Q5T0U7 xref: UniProtKB:Q5T0U8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004574 ! EPHB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0011729 ! EPHB2_HUMAN-Phosphotyrosine596 relationship: transforms_into CCO:B0011730 ! EPHB2_HUMAN-Phosphotyrosine602 relationship: transforms_into CCO:B0011731 ! EPHB2_HUMAN-Phosphothreonine775 relationship: transforms_into CCO:B0011732 ! EPHB2_HUMAN-Phosphotyrosine780 relationship: transforms_into CCO:B0011733 ! EPHB2_HUMAN-Phosphotyrosine930 [Term] id: CCO:B0001569 name: SHC1_HUMAN def: "SHC-transforming protein 1" [UniProtKB:P29353] synonym: "SH2 domain protein C1" EXACT [UniProtKB:P29353] synonym: "Src homology 2 domain-containing-transforming protein C1" EXACT [UniProtKB:P29353] xref: EMBL:AAB49972.1 xref: EMBL:AAH14158.1 xref: EMBL:AAH33925.1 xref: EMBL:BAF84832.1 xref: EMBL:BAF98733.1 xref: EMBL:CAA48251.1 xref: EMBL:CAA70977.1 xref: EMBL:CAI13248.1 xref: EMBL:CAI13249.1 xref: EMBL:CAI13250.1 xref: EMBL:CAI13251.1 xref: EMBL:CAI13254.1 xref: EMBL:EAW53168.1 xref: EMBL:EAW53169.1 xref: EMBL:EAW53170.1 xref: UniProtKB:O15290 xref: UniProtKB:P29353 xref: UniProtKB:Q5T180 xref: UniProtKB:Q5T183 xref: UniProtKB:Q5T184 xref: UniProtKB:Q5T185 xref: UniProtKB:Q5T186 xref: UniProtKB:Q8N4K5 xref: UniProtKB:Q96CL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005610 ! SHC1_human relationship: has_function CCO:F0001378 ! transmembrane receptor protein tyrosine kinase adaptor protein activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0005792 ! ndp52-shc1 physical interaction relationship: participates_in CCO:I0006285 ! igf1r-shc1-1 physical interaction relationship: participates_in CCO:I0006286 ! insr-shc1-1 physical interaction relationship: participates_in CCO:I0006335 ! sch1-app-3 physical interaction relationship: participates_in CCO:I0006444 ! erbb2-egfr physical interaction relationship: participates_in CCO:I0006445 ! erbb2-egfr-1 physical interaction relationship: participates_in CCO:I0006541 ! shc1-app-2 physical interaction relationship: participates_in CCO:I0006542 ! shc1-app-1 physical interaction relationship: participates_in CCO:I0006629 ! sch1-app-2 physical interaction relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007196 ! krt18-shc1-1 colocalization relationship: participates_in CCO:I0007304 ! erbb2-egfr-2 physical interaction relationship: participates_in CCO:I0007305 ! erbb2-egfr-3 physical interaction relationship: participates_in CCO:I0007390 ! sch1-app-4 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000718 ! regulation of epidermal growth factor receptor activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0014055 ! SHC1_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0014056 ! SHC1_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0014057 ! SHC1_HUMAN-Phosphotyrosine349 relationship: transforms_into CCO:B0014058 ! SHC1_HUMAN-Phosphotyrosine350 relationship: transforms_into CCO:B0014059 ! SHC1_HUMAN-Phosphotyrosine427 [Term] id: CCO:B0001570 name: PML_HUMAN def: "Probable transcription factor PML" [UniProtKB:P29590] synonym: "RING finger protein 71" EXACT [UniProtKB:P29590] synonym: "Tripartite motif-containing protein 19" EXACT [UniProtKB:P29590] xref: EMBL:AAA60125.1 xref: EMBL:AAA60351.1 xref: EMBL:AAA60352.1 xref: EMBL:AAA60388.1 xref: EMBL:AAA60390.1 xref: EMBL:AAG50180.1 xref: EMBL:BAB62809.1 xref: EMBL:CAA44841.1 xref: EMBL:CAA46026.1 xref: UniProtKB:P29590 xref: UniProtKB:P29591 xref: UniProtKB:P29592 xref: UniProtKB:P29593 xref: UniProtKB:Q00755 xref: UniProtKB:Q96S41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005344 ! PML_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006220 ! csnk2a1-pml-1 phosphorylation relationship: participates_in CCO:I0006271 ! pml-ubl_1-1 physical interaction relationship: participates_in CCO:I0006947 ! daxx-pml-2 colocalization relationship: participates_in CCO:I0006990 ! p53-pml-1 physical interaction relationship: participates_in CCO:I0007065 ! pml-daxx-1 physical interaction relationship: participates_in CCO:I0007066 ! daxx-pml-1 physical interaction relationship: participates_in CCO:I0007379 ! csnk2a1-pml phosphorylation relationship: participates_in CCO:P0000065 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis relationship: transforms_into CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0013573 ! PML_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0013574 ! PML_HUMAN-Phosphoserine504 relationship: transforms_into CCO:B0013575 ! PML_HUMAN-Phosphoserine505 relationship: transforms_into CCO:B0013576 ! PML_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0013577 ! PML_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0013578 ! PML_HUMAN-Phosphoserine527 relationship: transforms_into CCO:B0013579 ! PML_HUMAN-Phosphoserine530 relationship: transforms_into CCO:B0013580 ! PML_HUMAN-Phosphoserine535 relationship: transforms_into CCO:B0013581 ! PML_HUMAN-Phosphoserine560 relationship: transforms_into CCO:B0013582 ! PML_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0013583 ! PML_HUMAN-Phosphoserine562 relationship: transforms_into CCO:B0013584 ! PML_HUMAN-Phosphoserine565 relationship: transforms_into CCO:B0069429 ! PML_HUMAN-Phosphothreonine409 [Term] id: CCO:B0001571 name: 2AAA_HUMAN def: "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform" [UniProtKB:P30153] synonym: "Medium tumor antigen-associated 61 kDa protein" EXACT [UniProtKB:P30153] synonym: "PP2A, subunit A, PR65-alpha isoform" EXACT [UniProtKB:P30153] synonym: "PP2A, subunit A, R1-alpha isoform" EXACT [UniProtKB:P30153] xref: EMBL:AAA35531.1 xref: EMBL:AAA36399.1 xref: EMBL:AAH01537.1 xref: EMBL:CAG29336.1 xref: UniProtKB:P30153 xref: UniProtKB:Q13773 xref: UniProtKB:Q6ICQ3 xref: UniProtKB:Q96DH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004002 ! PPP2R1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006382 ! map3k3-ppp2r1a physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0008190 ! arih2-ppp2r1a physical interaction relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000639 ! regulation of DNA replication relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0001148 ! second-messenger-mediated signaling relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002083 ! negative regulation of tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002409 ! regulation of cell differentiation relationship: transforms_into CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 [Term] id: CCO:B0001572 name: CDC27_HUMAN def: "Cell division cycle protein 27 homolog" [UniProtKB:P30260] synonym: "CDC27Hs" EXACT [UniProtKB:P30260] synonym: "H-NUC" EXACT [UniProtKB:P30260] xref: EMBL:AAA60471.1 xref: EMBL:AAB34378.1 xref: EMBL:AAH11656.1 xref: EMBL:AAR89911.1 xref: UniProtKB:P30260 xref: UniProtKB:Q16349 xref: UniProtKB:Q96F35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004287 ! CDC27_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007814 ! cdc27-nek2-1 physical interaction relationship: participates_in CCO:I0007929 ! cdc27-nek2 physical interaction relationship: participates_in CCO:P0000102 ! mitotic metaphase/anaphase transition relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011068 ! CDC27_HUMAN-Phosphothreonine205 relationship: transforms_into CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: transforms_into CCO:B0011070 ! CDC27_HUMAN-Phosphothreonine244 relationship: transforms_into CCO:B0011071 ! CDC27_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0011072 ! CDC27_HUMAN-Phosphothreonine313 relationship: transforms_into CCO:B0011073 ! CDC27_HUMAN-Phosphoserine426 relationship: transforms_into CCO:B0011074 ! CDC27_HUMAN-Phosphothreonine430 relationship: transforms_into CCO:B0011075 ! CDC27_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0011076 ! CDC27_HUMAN-Phosphoserine438 relationship: transforms_into CCO:B0011077 ! CDC27_HUMAN-Phosphothreonine446 relationship: transforms_into CCO:B0064190 ! CDC27_HUMAN-Phosphoserine339 [Term] id: CCO:B0001573 name: CCND2_HUMAN def: "G1/S-specific cyclin-D2" [UniProtKB:P30279] xref: EMBL:AAA51926.1 xref: EMBL:AAA51928.1 xref: EMBL:AAH10958.1 xref: EMBL:AAH89384.1 xref: EMBL:AAM54041.1 xref: EMBL:AAV38650.1 xref: EMBL:BAA02802.1 xref: EMBL:CAA48493.1 xref: UniProtKB:P30279 xref: UniProtKB:Q13955 xref: UniProtKB:Q5U035 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004249 ! CCND2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005843 ! ccnd2-cdkn1a physical interaction relationship: participates_in CCO:I0005887 ! ccnd2-cdkn1b physical interaction relationship: participates_in CCO:I0006737 ! ccnd2-cdk4-1 physical interaction relationship: participates_in CCO:I0007903 ! cyclind2_cdk4_human direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000243 ! positive regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001574 name: CCND3_HUMAN def: "G1/S-specific cyclin-D3" [UniProtKB:P30281] xref: EMBL:AAA51927.1 xref: EMBL:AAA51929.1 xref: EMBL:AAA52137.1 xref: EMBL:AAH11616.1 xref: EMBL:AAM51826.1 xref: EMBL:CAI23491.1 xref: UniProtKB:P30281 xref: UniProtKB:Q5T8J0 xref: UniProtKB:Q96F49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004250 ! CCND3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005842 ! ccnd3-dtnbp1 physical interaction relationship: participates_in CCO:I0005845 ! ccnd3-efemp2 physical interaction relationship: participates_in CCO:I0005916 ! ccnd3-maf1 physical interaction relationship: participates_in CCO:I0005944 ! ccnd3-cdkn1b physical interaction relationship: participates_in CCO:I0005956 ! ccnd3-cdkn1a physical interaction relationship: participates_in CCO:I0005957 ! ccnd3-cdk4 physical interaction relationship: participates_in CCO:I0006098 ! mcm10-ccnd3 direct interaction relationship: participates_in CCO:I0006120 ! cdkn1a-ccnd3 direct interaction relationship: participates_in CCO:I0006129 ! cdk4-ccnd3 direct interaction relationship: participates_in CCO:I0006131 ! cdk6-ccnd3 direct interaction relationship: participates_in CCO:I0006738 ! ccnd2-cdk4-2 physical interaction relationship: participates_in CCO:I0007549 ! cdk4-ccnd3-1 physical interaction relationship: participates_in CCO:I0007550 ! cdk4-ccnd3-2 physical interaction relationship: participates_in CCO:I0007904 ! cyclind3_cdk4_human direct interaction relationship: participates_in CCO:I0007905 ! cyclind3_cdk6_human direct interaction relationship: participates_in CCO:I0008194 ! atp5c1-ccnd3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000243 ! positive regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001575 name: WEE1_HUMAN def: "Wee1-like protein kinase" [UniProtKB:P30291] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P30291] synonym: "Wee1A kinase" EXACT [UniProtKB:P30291] synonym: "WEE1hu" EXACT [UniProtKB:P30291] xref: EMBL:AAB60401.1 xref: EMBL:CAA43979.1 xref: EMBL:CAC14173.1 xref: UniProtKB:P30291 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005929 ! WEE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007598 ! skp2-skp1 physical interaction relationship: participates_in CCO:I0007599 ! fbxw11-skp1 physical interaction relationship: participates_in CCO:I0007600 ! btrc-skp1-1 physical interaction relationship: participates_in CCO:I0007601 ! btrc-wee1 physical interaction relationship: participates_in CCO:I0007602 ! fbxw11-wee1 physical interaction relationship: participates_in CCO:I0007915 ! wee1-plk1 phosphorylation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014689 ! WEE1_HUMAN-Phosphoserine123 relationship: transforms_into CCO:B0014690 ! WEE1_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0014691 ! WEE1_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0014692 ! WEE1_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0014693 ! WEE1_HUMAN-Phosphothreonine173 relationship: transforms_into CCO:B0014694 ! WEE1_HUMAN-Phosphoserine642 [Term] id: CCO:B0001576 name: MPIP1_HUMAN def: "M-phase inducer phosphatase 1" [UniProtKB:P30304] synonym: "Dual specificity phosphatase Cdc25A" EXACT [UniProtKB:P30304] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P30304] xref: EMBL:AAA58415.1 xref: EMBL:AAG41884.1 xref: EMBL:AAH07401.1 xref: EMBL:AAH18642.1 xref: EMBL:AAM77917.1 xref: EMBL:AAN11305.1 xref: UniProtKB:P30304 xref: UniProtKB:Q8IZH5 xref: UniProtKB:Q96IL3 xref: UniProtKB:Q9H2F2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005117 ! CDC25A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005818 ! ard1-cdc25a physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012983 ! MPIP1_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0012984 ! MPIP1_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0012985 ! MPIP1_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0012986 ! MPIP1_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0012987 ! MPIP1_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0012988 ! MPIP1_HUMAN-Phosphothreonine507 [Term] id: CCO:B0001577 name: MPIP2_HUMAN def: "M-phase inducer phosphatase 2" [UniProtKB:P30305] synonym: "Dual specificity phosphatase Cdc25B" EXACT [UniProtKB:P30305] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P30305] xref: EMBL:AAA58416.1 xref: EMBL:AAB21139.1 xref: EMBL:AAB94622.1 xref: EMBL:AAB94624.1 xref: EMBL:AAH06395.1 xref: EMBL:AAH09953.1 xref: EMBL:AAH51711.1 xref: EMBL:AAR26469.1 xref: EMBL:CAA65303.1 xref: EMBL:CAA92108.1 xref: EMBL:CAC17548.1 xref: EMBL:CAC17549.1 xref: EMBL:CAI18847.1 xref: UniProtKB:O43551 xref: UniProtKB:P30305 xref: UniProtKB:Q13971 xref: UniProtKB:Q5JX77 xref: UniProtKB:Q6RSS1 xref: UniProtKB:Q9BRA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005118 ! CDC25B_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: participates_in CCO:P0000038 ! mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001578 name: MPIP3_HUMAN def: "M-phase inducer phosphatase 3" [UniProtKB:P30307] synonym: "Dual specificity phosphatase Cdc25C" EXACT [UniProtKB:P30307] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P30307] xref: EMBL:AAA35666.1 xref: EMBL:AAG41885.1 xref: EMBL:AAG41887.1 xref: EMBL:AAG41888.1 xref: EMBL:AAH19089.1 xref: EMBL:AAL26835.1 xref: EMBL:AAR32098.1 xref: EMBL:CAC19192.1 xref: UniProtKB:P30307 xref: UniProtKB:Q96PL3 xref: UniProtKB:Q9H168 xref: UniProtKB:Q9H2E8 xref: UniProtKB:Q9H2E9 xref: UniProtKB:Q9H2F1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005119 ! CDC25C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007377 ! cdc25c-chek1-1 phosphorylation relationship: participates_in CCO:I0007513 ! ppp2r5d-cdc25c-1 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: participates_in CCO:P0000100 ! traversing start control point of mitotic cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012989 ! MPIP3_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0012990 ! MPIP3_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0068254 ! MPIP3_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0068255 ! MPIP3_HUMAN-Phosphothreonine48 relationship: transforms_into CCO:B0068256 ! MPIP3_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0068257 ! MPIP3_HUMAN-Phosphoserine61 relationship: transforms_into CCO:B0068258 ! MPIP3_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0068259 ! MPIP3_HUMAN-Phosphothreonine67 [Term] id: CCO:B0001579 name: UFO_HUMAN def: "Tyrosine-protein kinase receptor UFO precursor" [UniProtKB:P30530] synonym: "AXL oncogene" EXACT [UniProtKB:P30530] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P30530] xref: EMBL:AAA61243.1 xref: EMBL:AAB20305.1 xref: EMBL:CAA40338.1 xref: UniProtKB:P30530 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005877 ! AXL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0014576 ! UFO_HUMAN-Phosphotyrosine696 relationship: transforms_into CCO:B0071712 ! UFO_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0071713 ! UFO_HUMAN-Phosphotyrosine695 [Term] id: CCO:B0001580 name: CLIP1_HUMAN def: "CAP-Gly domain-containing linker protein 1" [UniProtKB:P30622] synonym: "CLIP-170" EXACT [UniProtKB:P30622] synonym: "Cytoplasmic linker protein 1" EXACT [UniProtKB:P30622] synonym: "Cytoplasmic linker protein 170 alpha-2" EXACT [UniProtKB:P30622] synonym: "Reed-Sternberg intermediate filament-associated protein" EXACT [UniProtKB:P30622] synonym: "Restin" EXACT [UniProtKB:P30622] xref: EMBL:AAA35693.1 xref: EMBL:CAA46050.1 xref: UniProtKB:P30622 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004370 ! CLIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0011261 ! CLIP1_HUMAN-Phosphothreonine182 relationship: transforms_into CCO:B0011262 ! CLIP1_HUMAN-Phosphoserine195 relationship: transforms_into CCO:B0011263 ! CLIP1_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0011264 ! CLIP1_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0035994 ! CLIP1_HUMAN-Phosphothreonine822 relationship: transforms_into CCO:B0064383 ! CLIP1_HUMAN-Phosphothreonine45 relationship: transforms_into CCO:B0064384 ! CLIP1_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0064385 ! CLIP1_HUMAN-Phosphothreonine140 relationship: transforms_into CCO:B0064386 ! CLIP1_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: transforms_into CCO:B0064388 ! CLIP1_HUMAN-Phosphoserine197 [Term] id: CCO:B0001581 name: COR1A_HUMAN def: "Coronin-1A" [UniProtKB:P31146] synonym: "Clipin-A" EXACT [UniProtKB:P31146] synonym: "Coronin-like protein A" EXACT [UniProtKB:P31146] synonym: "Coronin-like protein p57" EXACT [UniProtKB:P31146] synonym: "TACO" EXACT [UniProtKB:P31146] synonym: "Tryptophan aspartate-containing coat protein" EXACT [UniProtKB:P31146] xref: EMBL:AAA77058.1 xref: EMBL:AAI10375.1 xref: EMBL:AAI26386.1 xref: EMBL:AAI26388.1 xref: EMBL:AAM18516.1 xref: EMBL:BAA07940.1 xref: EMBL:CAA61482.1 xref: UniProtKB:P31146 xref: UniProtKB:Q2YD73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004385 ! CORO1A_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005873 ! phosphoinositide 3-kinase binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000187 ! phagocytic cup relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001056 ! cortical actin cytoskeleton relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001356 ! filamentous actin relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0001950 ! phagocytic vesicle relationship: participates_in CCO:P0003030 ! negative regulation of actin nucleation relationship: transforms_into CCO:B0011336 ! COR1A_HUMAN-N-acetylserine2 [Term] id: CCO:B0001582 name: MK04_HUMAN def: "Mitogen-activated protein kinase 4" [UniProtKB:P31152] synonym: "EC 2.7.11.24" EXACT [UniProtKB:P31152] synonym: "ERK-4" EXACT [UniProtKB:P31152] synonym: "Extracellular signal-regulated kinase 4" EXACT [UniProtKB:P31152] synonym: "MAP kinase isoform p63" EXACT [UniProtKB:P31152] synonym: "p63-MAPK" EXACT [UniProtKB:P31152] xref: EMBL:CAA42411.1 xref: UniProtKB:P31152 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005091 ! MAPK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0068206 ! MK04_HUMAN-Phosphoserine186 [Term] id: CCO:B0001583 name: FGF9_HUMAN def: "Glia-activating factor precursor" [UniProtKB:P31371] synonym: "FGF-9" EXACT [UniProtKB:P31371] synonym: "Fibroblast growth factor 9" EXACT [UniProtKB:P31371] synonym: "GAF" EXACT [UniProtKB:P31371] synonym: "HBGF-9" EXACT [UniProtKB:P31371] xref: EMBL:AAH69692.1 xref: EMBL:AAI03979.1 xref: EMBL:AAI03980.1 xref: EMBL:AAT74624.1 xref: EMBL:BAA03572.1 xref: EMBL:CAC17692.1 xref: UniProtKB:P31371 xref: UniProtKB:Q3SY32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004640 ! FGF9_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000525 ! positive regulation of mesenchymal cell proliferation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0001356 ! positive regulation of vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0002531 ! positive regulation of fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0002587 ! positive regulation of smoothened signaling pathway relationship: participates_in CCO:P0002851 ! regulation of timing of cell differentiation relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: participates_in CCO:P0003234 ! positive regulation of cardiac muscle cell proliferation [Term] id: CCO:B0001584 name: 1433S_HUMAN def: "14-3-3 protein sigma" [UniProtKB:P31947] synonym: "Epithelial cell marker protein 1" EXACT [UniProtKB:P31947] synonym: "Stratifin" EXACT [UniProtKB:P31947] xref: EMBL:AAA59546.1 xref: EMBL:AAC52029.1 xref: EMBL:AAC52030.1 xref: EMBL:AAH00329.1 xref: EMBL:AAH00995.1 xref: EMBL:AAH01550.1 xref: EMBL:AAH02995.1 xref: EMBL:AAH23552.1 xref: EMBL:CAA40623.1 xref: EMBL:CAB92118.1 xref: EMBL:CAG46703.1 xref: EMBL:CAG46724.1 xref: UniProtKB:P31947 xref: UniProtKB:Q6FH30 xref: UniProtKB:Q6FH51 xref: UniProtKB:Q96DH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003996 ! SFN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005727 ! bad-sfn physical interaction relationship: participates_in CCO:I0005751 ! plekhf2-sfn physical interaction relationship: participates_in CCO:I0005787 ! plk4-sfn physical interaction relationship: participates_in CCO:I0005794 ! mark3-sfn physical interaction relationship: participates_in CCO:I0005814 ! c8orf32-sfn physical interaction relationship: participates_in CCO:I0005824 ! chst1-sfn physical interaction relationship: participates_in CCO:I0005847 ! sfn-tbl3 physical interaction relationship: participates_in CCO:I0005919 ! q8wu02-sfn physical interaction relationship: participates_in CCO:I0005934 ! kiaa0514-sfn physical interaction relationship: participates_in CCO:I0006204 ! abl1-snf-1 physical interaction relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0006307 ! abl1-ywhab-1 physical interaction relationship: participates_in CCO:I0006511 ! map3k5-sfn-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:I0007888 ! plk4-sfn-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: transforms_into CCO:B0010370 ! 1433S_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0010371 ! 1433S_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0010372 ! 1433S_HUMAN-Phosphoserine248 [Term] id: CCO:B0001585 name: TF2H1_HUMAN def: "General transcription factor IIH subunit 1" [UniProtKB:P32780] synonym: "Basic transcription factor 2 62 kDa subunit" EXACT [UniProtKB:P32780] synonym: "BTF2-p62" EXACT [UniProtKB:P32780] synonym: "General transcription factor IIH polypeptide 1" EXACT [UniProtKB:P32780] synonym: "TFIIH basal transcription factor complex p62 subunit" EXACT [UniProtKB:P32780] xref: EMBL:AAA58399.1 xref: EMBL:AAH00365.1 xref: EMBL:AAH04452.1 xref: EMBL:AAN46740.1 xref: EMBL:BAB15621.1 xref: EMBL:CAC00685.1 xref: UniProtKB:P32780 xref: UniProtKB:Q9H5K5 xref: UniProtKB:Q9NQD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005763 ! GTF2H1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001846 ! RNA polymerase subunit kinase activity relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000279 ! holo TFIIH complex relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0001586 name: CKS2_HUMAN def: "Cyclin-dependent kinases regulatory subunit 2" [UniProtKB:P33552] synonym: "CKS-2" EXACT [UniProtKB:P33552] xref: EMBL:AAH06458.1 xref: EMBL:AAM22232.1 xref: EMBL:CAA38703.1 xref: UniProtKB:P33552 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004365 ! CKS2_human relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005867 ! cks2-tsc22d4 physical interaction relationship: participates_in CCO:I0008006 ! cks2-eef1a1 physical interaction relationship: participates_in CCO:I0008007 ! cks2-unc119 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000118 ! meiosis I relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001587 name: TTK_HUMAN def: "Dual specificity protein kinase TTK" [UniProtKB:P33981] synonym: "EC 2.7.12.1" EXACT [UniProtKB:P33981] synonym: "Phosphotyrosine picked threonine-protein kinase" EXACT [UniProtKB:P33981] synonym: "PYT" EXACT [UniProtKB:P33981] xref: EMBL:AAA61239.1 xref: EMBL:AAH00633.1 xref: EMBL:AAH32858.1 xref: EMBL:CAA49912.1 xref: EMBL:CAB87580.1 xref: EMBL:EAW48699.1 xref: UniProtKB:P33981 xref: UniProtKB:Q15272 xref: UniProtKB:Q5TCS0 xref: UniProtKB:Q9BW51 xref: UniProtKB:Q9NTM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005842 ! TTK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: participates_in CCO:P0000105 ! mitotic cell cycle spindle assembly checkpoint relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0014553 ! TTK_HUMAN-Phosphoserine821 relationship: transforms_into CCO:B0014554 ! TTK_HUMAN-Phosphoserine824 relationship: transforms_into CCO:B0071627 ! TTK_HUMAN-Phosphothreonine33 relationship: transforms_into CCO:B0071628 ! TTK_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0071629 ! TTK_HUMAN-Phosphoserine321 relationship: transforms_into CCO:B0071630 ! TTK_HUMAN-Phosphoserine393 [Term] id: CCO:B0001588 name: MCM5_HUMAN def: "DNA replication licensing factor MCM5" [UniProtKB:P33992] synonym: "CDC46 homolog" EXACT [UniProtKB:P33992] synonym: "P1-CDC46" EXACT [UniProtKB:P33992] xref: EMBL:AAH00142.1 xref: EMBL:AAH03656.1 xref: EMBL:AAO21127.1 xref: EMBL:BAA12176.1 xref: EMBL:CAA52802.2 xref: EMBL:CAG30403.1 xref: UniProtKB:O60785 xref: UniProtKB:P33992 xref: UniProtKB:Q14578 xref: UniProtKB:Q9BTJ4 xref: UniProtKB:Q9BWL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005040 ! MCM5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0005872 ! mcm5-mdfi physical interaction relationship: participates_in CCO:I0006077 ! orc1l-mcm5 direct interaction relationship: participates_in CCO:I0006080 ! mcm5-mcm3 direct interaction relationship: participates_in CCO:I0006086 ! mcm2-mcm5 direct interaction relationship: participates_in CCO:I0006116 ! orc3l-mcm5 direct interaction relationship: participates_in CCO:I0006118 ! orc5l-mcm5 direct interaction relationship: participates_in CCO:I0006144 ! mcm7-mcm5 direct interaction relationship: participates_in CCO:I0006151 ! cdkn2a-mcm5 direct interaction relationship: participates_in CCO:I0006423 ! nfkbia-mcm5 physical interaction relationship: participates_in CCO:I0006540 ! apc-ctbb1-1 physical interaction relationship: participates_in CCO:I0007540 ! mcm3-mcm5-1 physical interaction relationship: participates_in CCO:I0007541 ! mcm3-mcm5-2 physical interaction relationship: participates_in CCO:I0007914 ! mcm2-7_human physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001589 name: MCM7_HUMAN def: "DNA replication licensing factor MCM7" [UniProtKB:P33993] synonym: "CDC47 homolog" EXACT [UniProtKB:P33993] synonym: "P1.1-MCM3" EXACT [UniProtKB:P33993] xref: EMBL:AAH09398.1 xref: EMBL:AAH13375.1 xref: EMBL:BAA05839.1 xref: EMBL:BAA09534.1 xref: EMBL:CAA52803.1 xref: UniProtKB:P33993 xref: UniProtKB:Q15076 xref: UniProtKB:Q96D34 xref: UniProtKB:Q96GL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005042 ! MCM7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0001643 ! MCM complex relationship: participates_in CCO:I0005785 ! mcm7-rbm8a physical interaction relationship: participates_in CCO:I0005858 ! mbip-mcm7 physical interaction relationship: participates_in CCO:I0005964 ! smc1-mcm7-1 physical interaction relationship: participates_in CCO:I0005965 ! smc1-mcm7-3 physical interaction relationship: participates_in CCO:I0005966 ! mcm7-smc1-2 physical interaction relationship: participates_in CCO:I0005968 ! mcm6-mcm7-1 physical interaction relationship: participates_in CCO:I0006079 ! orc4l-mcm7 direct interaction relationship: participates_in CCO:I0006106 ! mcm10-mcm7 direct interaction relationship: participates_in CCO:I0006108 ! mcm2-mcm7 direct interaction relationship: participates_in CCO:I0006109 ! mcm7-orc3l direct interaction relationship: participates_in CCO:I0006126 ! orc6l-mcm7 direct interaction relationship: participates_in CCO:I0006144 ! mcm7-mcm5 direct interaction relationship: participates_in CCO:I0006153 ! mcm4-mcm7 direct interaction relationship: participates_in CCO:I0006227 ! smc1-mcm7-2 physical interaction relationship: participates_in CCO:I0006362 ! ikbkg-mcm7 physical interaction relationship: participates_in CCO:I0006424 ! nfkbia-mcm7 physical interaction relationship: participates_in CCO:I0006705 ! plk1-mcm7-3 physical interaction relationship: participates_in CCO:I0006855 ! plk1-mcm7-1 physical interaction relationship: participates_in CCO:I0006955 ! plk1-mcm7-2 physical interaction relationship: participates_in CCO:I0006957 ! plk1-mcm7-4 physical interaction relationship: participates_in CCO:I0007012 ! smc1-mcm7-4 direct interaction relationship: participates_in CCO:I0007013 ! smc1-mcm7-5 direct interaction relationship: participates_in CCO:I0007306 ! smc1-mcm7-6 physical interaction relationship: participates_in CCO:I0007542 ! mcm4-mcm6-1 physical interaction relationship: participates_in CCO:I0007821 ! mcm7-smc1-1 direct interaction relationship: participates_in CCO:I0007914 ! mcm2-7_human physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: transforms_into CCO:B0012839 ! MCM7_HUMAN-Phosphoserine549 relationship: transforms_into CCO:B0068067 ! MCM7_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0068068 ! MCM7_HUMAN-Phosphoserine500 [Term] id: CCO:B0001590 name: BTC_HUMAN def: "Probetacellulin precursor" [UniProtKB:P35070] xref: EMBL:AAB25452.1 xref: EMBL:AAH11618.1 xref: UniProtKB:P35070 xref: UniProtKB:Q96F48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004195 ! BTC_human relationship: has_function CCO:F0001456 ! epidermal growth factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001591 name: PHB_HUMAN def: "Prohibitin" [UniProtKB:P35232] xref: EMBL:AAB21614.1 xref: EMBL:AAH13401.1 xref: EMBL:AAH95460.1 xref: EMBL:AAO18340.1 xref: EMBL:AAP36079.1 xref: UniProtKB:P35232 xref: UniProtKB:Q4VBQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005306 ! PHB_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007380 ! phb-tp53-2 colocalization relationship: participates_in CCO:I0007491 ! phb-tp53-4 colocalization relationship: participates_in CCO:I0007607 ! phb-tp53-3 physical interaction relationship: participates_in CCO:I0007608 ! tp53-phb- physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: participates_in CCO:I0007802 ! phb-tp53-1 colocalization relationship: participates_in CCO:I0007924 ! phb-tp53 colocalization relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013500 ! PHB_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0013501 ! PHB_HUMAN-Phosphoserine254 relationship: transforms_into CCO:B0031363 ! PHB_HUMAN-Phosphotyrosine249 [Term] id: CCO:B0001592 name: MERL_HUMAN def: "Merlin" [UniProtKB:P35240] synonym: "Moesin-ezrin-radixin-like protein" EXACT [UniProtKB:P35240] synonym: "Neurofibromin-2" EXACT [UniProtKB:P35240] synonym: "Schwannomerlin" EXACT [UniProtKB:P35240] synonym: "Schwannomin" EXACT [UniProtKB:P35240] xref: EMBL:AAA36212.1 xref: EMBL:AAD48752.1 xref: EMBL:AAD48753.1 xref: EMBL:AAD48754.1 xref: EMBL:AAH03112.2 xref: EMBL:AAH20257.1 xref: EMBL:AAK54160.1 xref: EMBL:AAK54161.1 xref: EMBL:AAK54162.1 xref: EMBL:AAK54163.1 xref: EMBL:AAK54164.1 xref: EMBL:AAK54165.1 xref: EMBL:AAK54166.1 xref: EMBL:AAK54195.1 xref: EMBL:AAK54196.1 xref: EMBL:CAA51220.1 xref: EMBL:CAA76992.1 xref: EMBL:CAA76993.1 xref: EMBL:CAA80377.1 xref: EMBL:CAG30416.1 xref: UniProtKB:O95683 xref: UniProtKB:P35240 xref: UniProtKB:Q8WUJ2 xref: UniProtKB:Q969N0 xref: UniProtKB:Q969Q3 xref: UniProtKB:Q96T30 xref: UniProtKB:Q96T31 xref: UniProtKB:Q96T32 xref: UniProtKB:Q96T33 xref: UniProtKB:Q9BTW3 xref: UniProtKB:Q9UNG9 xref: UniProtKB:Q9UNH3 xref: UniProtKB:Q9UNH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005085 ! NF2_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000508 ! negative regulation of cell-matrix adhesion relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001057 ! Schwann cell proliferation relationship: participates_in CCO:P0001238 ! negative regulation of cell-cell adhesion relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0002083 ! negative regulation of tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002089 ! negative regulation of tyrosine phosphorylation of Stat5 protein relationship: participates_in CCO:P0002693 ! negative regulation of JAK-STAT cascade relationship: participates_in CCO:P0003108 ! positive regulation of stress fiber formation relationship: transforms_into CCO:B0012910 ! MERL_HUMAN-Phosphoserine518 [Term] id: CCO:B0001593 name: PGH2_HUMAN def: "Prostaglandin G/H synthase 2 precursor" [UniProtKB:P35354] synonym: "COX-2" EXACT [UniProtKB:P35354] synonym: "Cyclooxygenase-2" EXACT [UniProtKB:P35354] synonym: "EC 1.14.99.1" EXACT [UniProtKB:P35354] synonym: "PGH synthase 2" EXACT [UniProtKB:P35354] synonym: "PGHS-2" EXACT [UniProtKB:P35354] synonym: "PHS II" EXACT [UniProtKB:P35354] synonym: "Prostaglandin H2 synthase 2" EXACT [UniProtKB:P35354] synonym: "Prostaglandin-endoperoxide synthase 2" EXACT [UniProtKB:P35354] xref: EMBL:AAA35803.1 xref: EMBL:AAA57317.1 xref: EMBL:AAA58433.1 xref: EMBL:AAH13734.1 xref: EMBL:AAO38056.1 xref: EMBL:AAQ75702.1 xref: EMBL:AAR23927.1 xref: EMBL:BAA05698.1 xref: EMBL:CAB41240.1 xref: UniProtKB:P35354 xref: UniProtKB:Q16876 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005305 ! PTGS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0013499 ! PGH2_HUMAN-Phosphotyrosine446 [Term] id: CCO:B0001594 name: DDIT3_HUMAN def: "DNA damage-inducible transcript 3" [UniProtKB:P35638] synonym: "C/EBP-homologous protein" EXACT [UniProtKB:P35638] synonym: "CHOP" EXACT [UniProtKB:P35638] synonym: "DDIT-3" EXACT [UniProtKB:P35638] synonym: "Growth arrest and DNA-damage-inducible protein GADD153" EXACT [UniProtKB:P35638] xref: EMBL:AAB22646.1 xref: EMBL:AAB27103.1 xref: EMBL:AAH03637.1 xref: EMBL:AAW56077.1 xref: UniProtKB:P35638 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004452 ! DDIT3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005744 ! ddit3-dhrs10 physical interaction relationship: participates_in CCO:I0005849 ! c10orf119-ddit3 physical interaction relationship: participates_in CCO:I0005896 ! ddit3-spop physical interaction relationship: participates_in CCO:I0005951 ! batf-ddit3 physical interaction relationship: participates_in CCO:I0005961 ! cebpg-ddit3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000684 ! ER overload response relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: participates_in CCO:P0001650 ! negative regulation of CREB transcription factor activity relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0001595 name: AHR_HUMAN def: "Aryl hydrocarbon receptor precursor" [UniProtKB:P35869] synonym: "Ah receptor" EXACT [UniProtKB:P35869] synonym: "AhR" EXACT [UniProtKB:P35869] xref: EMBL:AAA16210.1 xref: EMBL:AAA92082.1 xref: EMBL:AAA92083.1 xref: EMBL:AAA92084.1 xref: EMBL:AAH69390.1 xref: EMBL:AAH70080.1 xref: EMBL:BAA03857.1 xref: EMBL:BAA07235.1 xref: UniProtKB:P35869 xref: UniProtKB:Q13728 xref: UniProtKB:Q13803 xref: UniProtKB:Q13804 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004038 ! AHR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0008202 ! Hsp90 protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006062 ! ahr-aip colocalization relationship: participates_in CCO:I0006063 ! ahr-aip-1 colocalization relationship: participates_in CCO:I0006457 ! ahr-rb1 physical interaction relationship: participates_in CCO:I0006458 ! ahr-rb1-1 physical interaction relationship: participates_in CCO:I0006479 ! ahr-arnt-3 physical interaction relationship: participates_in CCO:I0006480 ! ahr-arnt-4 physical interaction relationship: participates_in CCO:I0006544 ! ahr-erap_140-1 physical interaction relationship: participates_in CCO:I0006545 ! ahr-arnt-1 physical interaction relationship: participates_in CCO:I0006546 ! ahr-ncor2-1 physical interaction relationship: participates_in CCO:I0006547 ! ahr-arnt-2 physical interaction relationship: participates_in CCO:I0007813 ! ahr-aip-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0001596 name: PP1G_HUMAN def: "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit" [UniProtKB:P36873] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P36873] synonym: "PP-1G" EXACT [UniProtKB:P36873] synonym: "Protein phosphatase 1C catalytic subunit" EXACT [UniProtKB:P36873] xref: EMBL:AAA19823.1 xref: EMBL:AAH14073.1 xref: EMBL:CAA52169.1 xref: UniProtKB:P36873 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005358 ! PPP1CC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006366 ! ikbkg-ppp1cc physical interaction relationship: participates_in CCO:I0006385 ! map3k3-ppp1cc physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0069451 ! PP1G_HUMAN-Phosphothreonine307 [Term] id: CCO:B0001597 name: ACV1B_HUMAN def: "Activin receptor type-1B precursor" [UniProtKB:P36896] synonym: "Activin receptor-like kinase 4" EXACT [UniProtKB:P36896] synonym: "ACTR-IB" EXACT [UniProtKB:P36896] synonym: "ALK-4" EXACT [UniProtKB:P36896] synonym: "EC 2.7.11.30" EXACT [UniProtKB:P36896] synonym: "Serine/threonine-protein kinase receptor R2" EXACT [UniProtKB:P36896] synonym: "SKR2" EXACT [UniProtKB:P36896] xref: EMBL:AAA50246.1 xref: EMBL:AAA53349.1 xref: EMBL:AAA53350.1 xref: EMBL:AAA53351.1 xref: EMBL:AAA60555.1 xref: EMBL:AAA60556.1 xref: EMBL:AAH00254.1 xref: EMBL:AAH40531.1 xref: EMBL:AAP35735.1 xref: EMBL:CAA80258.1 xref: UniProtKB:P36896 xref: UniProtKB:Q15479 xref: UniProtKB:Q15480 xref: UniProtKB:Q15481 xref: UniProtKB:Q15482 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004024 ! ACVR1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001717 ! positive regulation of activin receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002462 ! positive regulation of erythrocyte differentiation relationship: transforms_into CCO:B0010450 ! ACV1B_HUMAN-Phosphotyrosine380 [Term] id: CCO:B0001598 name: BRCA1_HUMAN def: "Breast cancer type 1 susceptibility protein" [UniProtKB:P38398] synonym: "RING finger protein 53" EXACT [UniProtKB:P38398] xref: EMBL:AAA73985.1 xref: EMBL:AAB61673.1 xref: EMBL:AAC00049.1 xref: EMBL:AAC37594.1 xref: EMBL:AAP12647.1 xref: UniProtKB:O15129 xref: UniProtKB:P38398 xref: UniProtKB:Q7KYU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004186 ! BRCA1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006748 ! brca1-trrap-2 physical interaction relationship: participates_in CCO:I0006749 ! brca1-trrap-3 physical interaction relationship: participates_in CCO:I0006772 ! brca1-esr1 physical interaction relationship: participates_in CCO:I0006773 ! esr1-brca1-10 physical interaction relationship: participates_in CCO:I0006774 ! brca1-esr1-2 physical interaction relationship: participates_in CCO:I0006775 ! esr1-brca1-11 physical interaction relationship: participates_in CCO:I0006887 ! brca1-trrap-6 physical interaction relationship: participates_in CCO:I0006914 ! esr1-brca1-5 direct interaction relationship: participates_in CCO:I0006915 ! esr1-brca1-7 direct interaction relationship: participates_in CCO:I0007017 ! brca1-esr1-4 direct interaction relationship: participates_in CCO:I0007018 ! brca1-esr1-5 direct interaction relationship: participates_in CCO:I0007019 ! acaca-brca1-1 physical interaction relationship: participates_in CCO:I0007367 ! trrap-brca1 direct interaction relationship: participates_in CCO:I0007454 ! brca1-trrap physical interaction relationship: participates_in CCO:I0007455 ! brca1-trrap-1 physical interaction relationship: participates_in CCO:I0007492 ! esr1-brca1-1 direct interaction relationship: participates_in CCO:I0007493 ! esr1-brca1-2 direct interaction relationship: participates_in CCO:I0007494 ! esr1-brca1-3 direct interaction relationship: participates_in CCO:I0007495 ! esr1-brca1-6 direct interaction relationship: participates_in CCO:I0007523 ! brap-brca1 physical interaction relationship: participates_in CCO:I0007524 ! brca1-brap physical interaction relationship: participates_in CCO:I0007525 ! kpna2-brca1 physical interaction relationship: participates_in CCO:I0007594 ! brca1-trrap-4 direct interaction relationship: participates_in CCO:I0007595 ! brca1-trrap-5 physical interaction relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:I0007633 ! gfi1b-brca1 physical interaction relationship: participates_in CCO:I0007801 ! acaca-brca1 physical interaction relationship: participates_in CCO:I0007839 ! brca1-brap-2 physical interaction relationship: participates_in CCO:I0007840 ! kpna-bcra1 physical interaction relationship: participates_in CCO:I0007841 ! bcra1-kpna2 physical interaction relationship: participates_in CCO:I0007852 ! h2afx-brca1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000273 ! negative regulation of centriole replication relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter relationship: participates_in CCO:P0000683 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0001432 ! positive regulation of protein ubiquitination relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002514 ! negative regulation of fatty acid biosynthetic process relationship: participates_in CCO:P0002527 ! positive regulation of DNA repair relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010839 ! BRCA1_HUMAN-Phosphoserine840 relationship: transforms_into CCO:B0010840 ! BRCA1_HUMAN-Phosphoserine1143 relationship: transforms_into CCO:B0010841 ! BRCA1_HUMAN-Phosphoserine1211 relationship: transforms_into CCO:B0010842 ! BRCA1_HUMAN-Phosphoserine1212 relationship: transforms_into CCO:B0010843 ! BRCA1_HUMAN-Phosphoserine1217 relationship: transforms_into CCO:B0010844 ! BRCA1_HUMAN-Phosphoserine1218 relationship: transforms_into CCO:B0010845 ! BRCA1_HUMAN-Phosphoserine1239 relationship: transforms_into CCO:B0010846 ! BRCA1_HUMAN-Phosphoserine1245 relationship: transforms_into CCO:B0010847 ! BRCA1_HUMAN-Phosphoserine1280 relationship: transforms_into CCO:B0010848 ! BRCA1_HUMAN-Phosphoserine1330 relationship: transforms_into CCO:B0010849 ! BRCA1_HUMAN-Phosphoserine1336 relationship: transforms_into CCO:B0010850 ! BRCA1_HUMAN-Phosphoserine1342 relationship: transforms_into CCO:B0010851 ! BRCA1_HUMAN-Phosphoserine1387 relationship: transforms_into CCO:B0010852 ! BRCA1_HUMAN-Phosphothreonine1394 relationship: transforms_into CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 relationship: transforms_into CCO:B0010854 ! BRCA1_HUMAN-Phosphoserine1457 relationship: transforms_into CCO:B0010855 ! BRCA1_HUMAN-Phosphoserine1466 relationship: transforms_into CCO:B0010856 ! BRCA1_HUMAN-Phosphoserine1524 relationship: transforms_into CCO:B0010857 ! BRCA1_HUMAN-Phosphothreonine1700 relationship: transforms_into CCO:B0010858 ! BRCA1_HUMAN-Phosphothreonine1720 relationship: transforms_into CCO:B0048180 ! BRCA1_HUMAN-Phosphoserine1542 relationship: transforms_into CCO:B0063982 ! BRCA1_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0063983 ! BRCA1_HUMAN-Phosphoserine398 relationship: transforms_into CCO:B0063984 ! BRCA1_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0063985 ! BRCA1_HUMAN-Phosphoserine753 [Term] id: CCO:B0001599 name: CDN1A_HUMAN def: "Cyclin-dependent kinase inhibitor 1" [UniProtKB:P38936] synonym: "CDK-interacting protein 1" EXACT [UniProtKB:P38936] synonym: "MDA-6" EXACT [UniProtKB:P38936] synonym: "Melanoma differentiation-associated protein 6" EXACT [UniProtKB:P38936] synonym: "p21" EXACT [UniProtKB:P38936] xref: EMBL:AAA16109.1 xref: EMBL:AAA19811.1 xref: EMBL:AAA85641.1 xref: EMBL:AAB29246.1 xref: EMBL:AAB59559.1 xref: EMBL:AAB59560.1 xref: EMBL:AAC04313.1 xref: EMBL:AAH00275.1 xref: EMBL:AAH00312.1 xref: EMBL:AAH01935.1 xref: EMBL:AAH13967.1 xref: EMBL:AAM11787.1 xref: EMBL:CAB06656.1 xref: UniProtKB:P38936 xref: UniProtKB:Q14010 xref: UniProtKB:Q9BUT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004309 ! CDKN1A_human relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004391 ! cyclin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005769 ! cdkn1a-tex11 physical interaction relationship: participates_in CCO:I0005843 ! ccnd2-cdkn1a physical interaction relationship: participates_in CCO:I0005956 ! ccnd3-cdkn1a physical interaction relationship: participates_in CCO:I0005962 ! cdkn1a-pcna physical interaction relationship: participates_in CCO:I0006120 ! cdkn1a-ccnd3 direct interaction relationship: participates_in CCO:I0006132 ! cdkn1a-ccne2 direct interaction relationship: participates_in CCO:I0006135 ! cdkn1a-cdc45l direct interaction relationship: participates_in CCO:I0006136 ! cdkn1a-hscdc6 direct interaction relationship: participates_in CCO:I0006137 ! cdkn1a-cdc7 direct interaction relationship: participates_in CCO:I0006140 ! cdkn1a-ccnd1 direct interaction relationship: participates_in CCO:I0006147 ! cdkn1a-hscdc5 direct interaction relationship: participates_in CCO:I0006148 ! cdkn1a-cdk6 direct interaction relationship: participates_in CCO:I0006149 ! cdkn1a-ccnb2 direct interaction relationship: participates_in CCO:I0006152 ! cdkn1a-cdk4 direct interaction relationship: participates_in CCO:I0006156 ! cdkn1a-ccna1 direct interaction relationship: participates_in CCO:I0006159 ! cdkn1a-cdk2 direct interaction relationship: participates_in CCO:I0006160 ! cdkn1a-gmnn direct interaction relationship: participates_in CCO:I0006161 ! cdkn1a-mcm10 direct interaction relationship: participates_in CCO:I0006290 ! cdkn1a-ccne1-2 physical interaction relationship: participates_in CCO:I0006293 ! cdkn1a-ccne1-3 physical interaction relationship: participates_in CCO:I0006294 ! cdkn1a-cdk2-1 physical interaction relationship: participates_in CCO:I0006297 ! cdkn1a-ccne1-4 physical interaction relationship: participates_in CCO:I0006862 ! cdk4-ccnd1-5 physical interaction relationship: participates_in CCO:I0007091 ! cdkn1a-ccnd1-1 physical interaction relationship: participates_in CCO:I0007349 ! cdkn1a-ccne1-5 physical interaction relationship: participates_in CCO:I0007548 ! cdk4-cdkn1a-1 physical interaction relationship: participates_in CCO:I0007853 ! cdkn1a-ccne1-6 physical interaction relationship: participates_in CCO:I0007854 ! cdkn1a-ccnd1-2 physical interaction relationship: participates_in CCO:I0007855 ! cdkn1a-ccna1-1 physical interaction relationship: participates_in CCO:I0007856 ! cdkn1a-ccne1-7 physical interaction relationship: participates_in CCO:I0007857 ! cdkn1a-cdk2-2 physical interaction relationship: participates_in CCO:I0008305 ! rab1a-cdkn1a physical interaction relationship: participates_in CCO:I0008365 ! c7orf20-cdkn1a physical interaction relationship: participates_in CCO:I0008371 ! cdkn1a-gnb2l1 physical interaction relationship: participates_in CCO:I0008372 ! cdkn1a-hdac11 physical interaction relationship: participates_in CCO:I0008456 ! cdkn1a-flj20580 physical interaction relationship: participates_in CCO:I0008457 ! cdkn1a-itgb1bp3 physical interaction relationship: participates_in CCO:I0008458 ! cdkn1a-slc25a11 physical interaction relationship: participates_in CCO:I0008481 ! kiaa0998-cdkn1a physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002153 ! positive regulation of non-apoptotic programmed cell death relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: transforms_into CCO:B0011121 ! CDN1A_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0011122 ! CDN1A_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0011123 ! CDN1A_HUMAN-Phosphothreonine145 relationship: transforms_into CCO:B0011124 ! CDN1A_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0011125 ! CDN1A_HUMAN-Phosphoserine160 [Term] id: CCO:B0001600 name: VHL_HUMAN def: "Von Hippel-Lindau disease tumor suppressor" [UniProtKB:P40337] synonym: "Protein G7" EXACT [UniProtKB:P40337] synonym: "pVHL" EXACT [UniProtKB:P40337] xref: EMBL:AAA98614.1 xref: EMBL:AAB64200.1 xref: EMBL:CAA65343.1 xref: UniProtKB:P40337 xref: UniProtKB:Q13599 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005902 ! VHL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006820 ! hif1a-vhl-1 physical interaction relationship: participates_in CCO:I0006845 ! tceb1-tceb2-vh1 physical interaction relationship: participates_in CCO:I0007175 ! hif1a-os9-4 direct interaction relationship: participates_in CCO:I0007176 ! hif1a-vhl physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0001601 name: MLH1_HUMAN def: "DNA mismatch repair protein Mlh1" [UniProtKB:P40692] synonym: "MutL protein homolog 1" EXACT [UniProtKB:P40692] xref: EMBL:AAA17374.1 xref: EMBL:AAA82079.1 xref: EMBL:AAA85687.1 xref: EMBL:AAC50285.1 xref: EMBL:AAH06850.1 xref: EMBL:AAO22994.1 xref: UniProtKB:P40692 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005100 ! MLH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005754 ! ap2b1-mlh1 physical interaction relationship: participates_in CCO:I0005761 ! mlh1-trim29 physical interaction relationship: participates_in CCO:I0005834 ! mlh1-zc3h11a physical interaction relationship: participates_in CCO:I0005854 ! frmd6-mlh1 physical interaction relationship: participates_in CCO:I0005931 ! mlh1-ubox5 physical interaction relationship: participates_in CCO:I0007475 ! pms2-mlh1 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0068226 ! MLH1_HUMAN-Phosphoserine477 [Term] id: CCO:B0001602 name: CCNF_HUMAN def: "G2/mitotic-specific cyclin-F" [UniProtKB:P41002] xref: EMBL:AAB60342.1 xref: EMBL:AAH12349.1 xref: EMBL:CAA85308.1 xref: UniProtKB:P41002 xref: UniProtKB:Q96EG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004253 ! CCNF_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001603 name: BCL6_HUMAN def: "B-cell lymphoma 6 protein" [UniProtKB:P41182] synonym: "BCL-5" EXACT [UniProtKB:P41182] synonym: "BCL-6" EXACT [UniProtKB:P41182] synonym: "LAZ-3 protein" EXACT [UniProtKB:P41182] synonym: "Zinc finger and BTB domain-containing protein 27" EXACT [UniProtKB:P41182] synonym: "Zinc finger protein 51" EXACT [UniProtKB:P41182] xref: EMBL:AAC50054.1 xref: EMBL:CAA79937.1 xref: UniProtKB:P41182 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004153 ! BCL6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000265 ! replication fork relationship: participates_in CCO:I0007582 ! bcl6-hdac4 physical interaction relationship: participates_in CCO:I0007583 ! hdac4-bcl6 physical interaction relationship: participates_in CCO:I0007584 ! pkc-bcl6 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000508 ! negative regulation of cell-matrix adhesion relationship: participates_in CCO:P0000613 ! negative regulation of B cell apoptosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0001590 ! regulation of Rho GTPase activity relationship: participates_in CCO:P0001986 ! negative regulation of Rho protein signal transduction relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002203 ! regulation of memory T cell differentiation relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: participates_in CCO:P0002443 ! negative regulation of T-helper 2 cell differentiation relationship: participates_in CCO:P0002805 ! negative regulation of isotype switching to IgE isotypes relationship: participates_in CCO:P0003073 ! positive regulation of cell motility [Term] id: CCO:B0001604 name: CETN2_HUMAN def: "Centrin-2" [UniProtKB:P41208] synonym: "Caltractin isoform 1" EXACT [UniProtKB:P41208] xref: EMBL:AAH05334.1 xref: EMBL:AAH13873.1 xref: EMBL:AAP35920.1 xref: EMBL:AAW82436.1 xref: EMBL:CAA51467.1 xref: UniProtKB:P41208 xref: UniProtKB:Q53XW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004333 ! CETN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011181 ! CETN2_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0011182 ! CETN2_HUMAN-Phosphothreonine26 [Term] id: CCO:B0001605 name: RGS2_HUMAN def: "Regulator of G-protein signaling 2" [UniProtKB:P41220] synonym: "Cell growth-inhibiting gene 31 protein" EXACT [UniProtKB:P41220] synonym: "G0/G1 switch regulatory protein 8" EXACT [UniProtKB:P41220] synonym: "RGS2" EXACT [UniProtKB:P41220] xref: EMBL:AAA20680.1 xref: EMBL:AAC37587.1 xref: EMBL:AAH07049.1 xref: EMBL:AAM12640.1 xref: EMBL:AAP35728.1 xref: EMBL:AAY40361.1 xref: EMBL:BAG36420.1 xref: EMBL:CAB62512.1 xref: EMBL:CAG33691.1 xref: EMBL:EAW91231.1 xref: UniProtKB:P41220 xref: UniProtKB:Q6I9U5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005480 ! RGS2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008043 ! rgs2-git1 physical interaction relationship: participates_in CCO:I0008157 ! rgs2-ddr1 physical interaction relationship: participates_in CCO:I0008158 ! rgs2-hspa8 physical interaction relationship: participates_in CCO:I0008309 ! rgs2-arfgap1 physical interaction relationship: participates_in CCO:I0008310 ! rgs2-dncl1 physical interaction relationship: participates_in CCO:I0008311 ! rgs2-park2 physical interaction relationship: participates_in CCO:I0008312 ! rgs2-prkcsh physical interaction relationship: participates_in CCO:I0008427 ! rgs2-wdr74 physical interaction relationship: participates_in CCO:I0008429 ! rgs2-nipsnap1 physical interaction relationship: participates_in CCO:I0008430 ! rgs2-vps29 physical interaction relationship: participates_in CCO:I0008496 ! rgs2-ctsb physical interaction relationship: participates_in CCO:I0008497 ! rgs2-scn5a physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0001606 name: CSK_HUMAN def: "Tyrosine-protein kinase CSK" [UniProtKB:P41240] synonym: "C-SRC kinase" EXACT [UniProtKB:P41240] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P41240] synonym: "Protein-tyrosine kinase CYL" EXACT [UniProtKB:P41240] xref: EMBL:AAI04848.1 xref: EMBL:AAI04876.1 xref: EMBL:AAI06074.1 xref: EMBL:AAY57329.1 xref: EMBL:CAA42556.1 xref: EMBL:CAA42713.1 xref: EMBL:CAB58562.1 xref: EMBL:CAG46758.1 xref: UniProtKB:P41240 xref: UniProtKB:Q2M3N2 xref: UniProtKB:Q6FGZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004405 ! CSK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0011354 ! CSK_HUMAN-Phosphotyrosine184 relationship: transforms_into CCO:B0011355 ! CSK_HUMAN-Phosphotyrosine304 relationship: transforms_into CCO:B0011356 ! CSK_HUMAN-Phosphotyrosine416 [Term] id: CCO:B0001607 name: NBL1_HUMAN def: "Neuroblastoma suppressor of tumorigenicity 1 precursor" [UniProtKB:P41271] synonym: "DAN domain family member 1" EXACT [UniProtKB:P41271] synonym: "N03" EXACT [UniProtKB:P41271] synonym: "Zinc finger protein DAN" EXACT [UniProtKB:P41271] xref: EMBL:AAH12037.1 xref: EMBL:AAL15440.1 xref: EMBL:BAA05671.1 xref: EMBL:BAA92265.1 xref: UniProtKB:P41271 xref: UniProtKB:Q96L68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005158 ! NBL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001608 name: STAT1_HUMAN def: "Signal transducer and activator of transcription 1-alpha/beta" [UniProtKB:P42224] synonym: "Transcription factor ISGF-3 components p91/p84" EXACT [UniProtKB:P42224] xref: EMBL:AAB64012.1 xref: EMBL:AAH02704.1 xref: EMBL:AAW56072.1 xref: EMBL:AAY24183.1 xref: UniProtKB:P42224 xref: UniProtKB:Q53S88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005686 ! STAT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001376 ! hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005762 ! lmo2-stat1 physical interaction relationship: participates_in CCO:I0007050 ! nmi-stat1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000777 ! tyrosine phosphorylation of STAT protein relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014243 ! STAT1_HUMAN-Phosphotyrosine701 relationship: transforms_into CCO:B0014244 ! STAT1_HUMAN-Phosphoserine727 [Term] id: CCO:B0001609 name: STA5A_HUMAN def: "Signal transducer and activator of transcription 5A" [UniProtKB:P42229] xref: EMBL:AAA73962.1 xref: EMBL:AAB06589.1 xref: EMBL:AAH27036.1 xref: UniProtKB:P42229 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005681 ! STAT5A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005853 ! magea12-stat5a physical interaction relationship: participates_in CCO:I0005926 ! hhgp-stat5a physical interaction relationship: participates_in CCO:I0007053 ! nmi-stat5a-1 physical interaction relationship: participates_in CCO:I0007185 ! cbp-stat5a-1 physical interaction relationship: participates_in CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001141 ! regulation of steroid metabolic process relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001342 ! regulation of epithelial cell differentiation relationship: participates_in CCO:P0002043 ! positive regulation of activated T cell proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002393 ! positive regulation of B cell differentiation relationship: participates_in CCO:P0002461 ! negative regulation of erythrocyte differentiation relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0014235 ! STA5A_HUMAN-Phosphotyrosine694 relationship: transforms_into CCO:B0014236 ! STA5A_HUMAN-Phosphoserine780 relationship: transforms_into CCO:B0036032 ! STA5A_HUMAN-Phosphothreonine372 relationship: transforms_into CCO:B0036033 ! STA5A_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0070946 ! STA5A_HUMAN-Phosphoserine193 [Term] id: CCO:B0001610 name: PK3CB_HUMAN def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform" [UniProtKB:P42338] synonym: "EC 2.7.1.153" EXACT [UniProtKB:P42338] synonym: "PI3-kinase p110 subunit beta" EXACT [UniProtKB:P42338] synonym: "PI3K" EXACT [UniProtKB:P42338] synonym: "PI3Kbeta" EXACT [UniProtKB:P42338] synonym: "PtdIns-3-kinase p110" EXACT [UniProtKB:P42338] xref: EMBL:AAB29081.1 xref: EMBL:AAI14433.1 xref: EMBL:CAC21449.1 xref: UniProtKB:P42338 xref: UniProtKB:Q24JU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005321 ! PIK3CB_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0005875 ! insulin receptor substrate binding relationship: has_function CCO:F0006278 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000507 ! regulation of cell-matrix adhesion relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0002022 ! embryonic cleavage relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0001611 name: FRAP_HUMAN def: "FKBP12-rapamycin complex-associated protein" [UniProtKB:P42345] synonym: "FK506-binding protein 12-rapamycin complex-associated protein 1" EXACT [UniProtKB:P42345] synonym: "Mammalian target of rapamycin" EXACT [UniProtKB:P42345] synonym: "mTOR" EXACT [UniProtKB:P42345] synonym: "Rapamycin target protein" EXACT [UniProtKB:P42345] synonym: "RAPT1" EXACT [UniProtKB:P42345] xref: EMBL:AAA58486.1 xref: EMBL:AAC39933.1 xref: EMBL:AAC41713.1 xref: EMBL:AAI17167.1 xref: EMBL:CAC15570.1 xref: EMBL:CAI17228.1 xref: EMBL:CAI22105.1 xref: EMBL:CAI22145.1 xref: UniProtKB:P42345 xref: UniProtKB:Q5TER1 xref: UniProtKB:Q6LE87 xref: UniProtKB:Q96QG3 xref: UniProtKB:Q9Y4I3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004657 ! FRAP1_human relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0008071 ! phosphoprotein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006418 ! traf2-frap1 physical interaction relationship: participates_in CCO:I0006794 ! fkbp1a-frap1-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0011893 ! FRAP_HUMAN-Phosphoserine2478 relationship: transforms_into CCO:B0011894 ! FRAP_HUMAN-Phosphoserine2481 relationship: transforms_into CCO:B0039438 ! FRAP_HUMAN-Phosphothreonine1162 [Term] id: CCO:B0001612 name: MATK_HUMAN def: "Megakaryocyte-associated tyrosine-protein kinase" [UniProtKB:P42679] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P42679] synonym: "Hematopoietic consensus tyrosine-lacking kinase" EXACT [UniProtKB:P42679] synonym: "Protein kinase HYL" EXACT [UniProtKB:P42679] synonym: "Tyrosine-protein kinase CTK" EXACT [UniProtKB:P42679] xref: EMBL:AAA16703.1 xref: EMBL:AAC60645.1 xref: EMBL:AAC62843.1 xref: EMBL:AAH00114.1 xref: EMBL:AAH03109.1 xref: EMBL:CAA54493.1 xref: UniProtKB:P42679 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005031 ! MATK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005922 ! ewsr1-matk physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0012780 ! MATK_HUMAN-Phosphoserine501 relationship: transforms_into CCO:B0012781 ! MATK_HUMAN-Phosphoserine504 [Term] id: CCO:B0001613 name: FRK_HUMAN def: "Tyrosine-protein kinase FRK" [UniProtKB:P42685] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P42685] synonym: "FYN-related kinase" EXACT [UniProtKB:P42685] synonym: "Nuclear tyrosine protein kinase RAK" EXACT [UniProtKB:P42685] xref: EMBL:AAA18284.1 xref: EMBL:AAC50116.1 xref: EMBL:AAH12916.1 xref: EMBL:CAB87592.2 xref: EMBL:CAI16469.1 xref: EMBL:EAW48241.1 xref: UniProtKB:P42685 xref: UniProtKB:Q13128 xref: UniProtKB:Q9NTR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004659 ! FRK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0011896 ! FRK_HUMAN-Phosphotyrosine387 relationship: transforms_into CCO:B0011897 ! FRK_HUMAN-Phosphotyrosine497 relationship: transforms_into CCO:B0066279 ! FRK_HUMAN-Phosphotyrosine46 [Term] id: CCO:B0001614 name: CNDD3_HUMAN def: "Condensin-2 complex subunit D3" [UniProtKB:P42695] synonym: "hCAP-D3" EXACT [UniProtKB:P42695] synonym: "Non-SMC condensin II complex subunit D3" EXACT [UniProtKB:P42695] xref: EMBL:AAC28639.1 xref: EMBL:AAH98398.1 xref: EMBL:BAA06224.1 xref: EMBL:EAW67824.1 xref: UniProtKB:A6NFS2 xref: UniProtKB:P42695 xref: UniProtKB:Q4KMQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004379 ! NCAPD3_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000126 ! nuclear condensin complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011313 ! CNDD3_HUMAN-Phosphoserine531 relationship: transforms_into CCO:B0011314 ! CNDD3_HUMAN-Phosphotyrosine972 relationship: transforms_into CCO:B0011315 ! CNDD3_HUMAN-Phosphoserine1384 relationship: transforms_into CCO:B0011316 ! CNDD3_HUMAN-Phosphoserine1393 relationship: transforms_into CCO:B0035995 ! CNDD3_HUMAN-Phosphoserine1357 relationship: transforms_into CCO:B0048205 ! CNDD3_HUMAN-Phosphoserine1329 relationship: transforms_into CCO:B0048206 ! CNDD3_HUMAN-Phosphothreonine1331 relationship: transforms_into CCO:B0064414 ! CNDD3_HUMAN-Phosphoserine1348 [Term] id: CCO:B0001615 name: CD2A1_HUMAN def: "Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3" [UniProtKB:P42771] synonym: "CDK4I" EXACT [UniProtKB:P42771] synonym: "Cyclin-dependent kinase 4 inhibitor A" EXACT [UniProtKB:P42771] synonym: "MTS-1" EXACT [UniProtKB:P42771] synonym: "Multiple tumor suppressor 1" EXACT [UniProtKB:P42771] synonym: "p16-INK4" EXACT [UniProtKB:P42771] synonym: "p16-INK4a" EXACT [UniProtKB:P42771] synonym: "p16INK4A" EXACT [UniProtKB:P42771] xref: EMBL:AAA92554.1 xref: EMBL:AAB60645.1 xref: EMBL:AAD11437.1 xref: EMBL:AAD14048.1 xref: EMBL:AAD14050.1 xref: EMBL:AAH15960.2 xref: EMBL:AAH21998.2 xref: EMBL:AAR05391.1 xref: EMBL:BAB91133.1 xref: EMBL:CAA63870.1 xref: EMBL:CAH70600.1 xref: UniProtKB:O95440 xref: UniProtKB:P42771 xref: UniProtKB:Q15191 xref: UniProtKB:Q5VVJ5 xref: UniProtKB:Q96B52 xref: UniProtKB:Q9NP05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004271 ! CDKN2A_human relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006112 ! cdk6-cdkn2a direct interaction relationship: participates_in CCO:I0006113 ! cdk4-cdkn2a direct interaction relationship: participates_in CCO:I0006115 ! cdkn2a-gmnn direct interaction relationship: participates_in CCO:I0006117 ! orc4l-cdkn2a direct interaction relationship: participates_in CCO:I0006128 ! cdkn2a-hscdc6 direct interaction relationship: participates_in CCO:I0006133 ! cdkn2a-orc5l direct interaction relationship: participates_in CCO:I0006139 ! cdkn2a-cdc45l direct interaction relationship: participates_in CCO:I0006141 ! cdkn2a-cdc7 direct interaction relationship: participates_in CCO:I0006142 ! mcm2-cdkn2a direct interaction relationship: participates_in CCO:I0006145 ! cdkn2a-mcm10 direct interaction relationship: participates_in CCO:I0006151 ! cdkn2a-mcm5 direct interaction relationship: participates_in CCO:I0006792 ! cdk6-cdkn2a-1 direct interaction relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000508 ! negative regulation of cell-matrix adhesion relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001541 ! negative regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation [Term] id: CCO:B0001616 name: CDN2B_HUMAN def: "Cyclin-dependent kinase 4 inhibitor B" [UniProtKB:P42772] synonym: "MTS-2" EXACT [UniProtKB:P42772] synonym: "Multiple tumor suppressor 2" EXACT [UniProtKB:P42772] synonym: "p14-INK4b" EXACT [UniProtKB:P42772] synonym: "p15-INK4b" EXACT [UniProtKB:P42772] synonym: "p15INK4B" EXACT [UniProtKB:P42772] xref: EMBL:AAA50282.1 xref: EMBL:AAC50075.1 xref: EMBL:AAD14049.1 xref: EMBL:AAH14469.1 xref: EMBL:AAM44859.1 xref: EMBL:CAG38766.1 xref: EMBL:CAH70603.1 xref: UniProtKB:P42772 xref: UniProtKB:Q6FI09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004312 ! CDKN2B_human relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005897 ! cdkn2b-magea11 physical interaction relationship: participates_in CCO:I0005946 ! cdk4-cdkn2b-1 physical interaction relationship: participates_in CCO:I0007981 ! cdk4-cdkn2b physical interaction relationship: participates_in CCO:I0008081 ! cdkn2b-kiaa1377 physical interaction relationship: participates_in CCO:I0008191 ! arpc3-cdkn2b physical interaction relationship: participates_in CCO:I0008212 ! cdkn2b-ikbkap physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000188 ! G1/S transition checkpoint relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001272 ! positive regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation [Term] id: CCO:B0001617 name: CDN2C_HUMAN def: "Cyclin-dependent kinase 4 inhibitor C" [UniProtKB:P42773] synonym: "Cyclin-dependent kinase 6 inhibitor" EXACT [UniProtKB:P42773] synonym: "p18-INK4c" EXACT [UniProtKB:P42773] synonym: "p18-INK6" EXACT [UniProtKB:P42773] xref: EMBL:AAC39782.1 xref: EMBL:AAC39783.1 xref: EMBL:AAC50074.1 xref: EMBL:AAH00598.1 xref: EMBL:AAH05041.1 xref: EMBL:AAH16173.1 xref: EMBL:AAM11873.1 xref: UniProtKB:P42773 xref: UniProtKB:Q8TB83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004313 ! CDKN2C_human relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007982 ! cdkn2c-tp53 physical interaction relationship: participates_in CCO:I0007983 ! cdkn2c-unc119 physical interaction relationship: participates_in CCO:I0008005 ! cdkn2c-rif1 physical interaction relationship: participates_in CCO:I0008026 ! nhp2l1-cdkn2c physical interaction relationship: participates_in CCO:I0008082 ! cdkn2c-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0008083 ! cdkn2c-drap1 physical interaction relationship: participates_in CCO:I0008084 ! cdkn2c-tle1 physical interaction relationship: participates_in CCO:I0008213 ! cdkn2c-aplp1 physical interaction relationship: participates_in CCO:I0008214 ! cdkn2c-cops6 physical interaction relationship: participates_in CCO:I0008215 ! cdkn2c-gdf9 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation [Term] id: CCO:B0001618 name: LIS1_HUMAN def: "Platelet-activating factor acetylhydrolase IB subunit alpha" [UniProtKB:P43034] synonym: "LIS-1" EXACT [UniProtKB:P43034] synonym: "Lissencephaly-1 protein" EXACT [UniProtKB:P43034] synonym: "PAF acetylhydrolase 45 kDa subunit" EXACT [UniProtKB:P43034] synonym: "PAF-AH 45 kDa subunit" EXACT [UniProtKB:P43034] synonym: "PAF-AH alpha" EXACT [UniProtKB:P43034] synonym: "PAFAH alpha" EXACT [UniProtKB:P43034] xref: EMBL:AAA02880.1 xref: EMBL:AAA02881.1 xref: EMBL:AAA02882.1 xref: EMBL:AAC51111.1 xref: EMBL:AAH64638.1 xref: EMBL:AAK92483.1 xref: EMBL:AAL34972.1 xref: EMBL:AAL34973.1 xref: EMBL:CAD98141.1 xref: UniProtKB:P43034 xref: UniProtKB:Q8WZ88 xref: UniProtKB:Q8WZ89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004983 ! PAFAH1B1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005832 ! phospholipase binding relationship: has_function CCO:F0006133 ! dynein binding relationship: has_function CCO:F0008071 ! phosphoprotein binding relationship: has_function CCO:F0008391 ! dynactin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000042 ! astral microtubule relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001172 ! leading edge relationship: located_in CCO:C0001280 ! motile primary cilium relationship: located_in CCO:C0001281 ! nonmotile primary cilium relationship: located_in CCO:C0001358 ! nuclear membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0006596 ! disc1-pafah1b1 physical interaction relationship: participates_in CCO:I0006597 ! disc1-pafah1b1-1 physical interaction relationship: participates_in CCO:I0007489 ! ndel1_pafah1b1_1 physical interaction relationship: participates_in CCO:I0007490 ! pafah1b1_ndel1_1 physical interaction relationship: participates_in CCO:I0008400 ! kars-pafah1b1 physical interaction relationship: participates_in CCO:P0000028 ! establishment of mitotic spindle orientation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0001590 ! regulation of Rho GTPase activity relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0031335 ! LIS1_HUMAN-Phosphotyrosine28 relationship: transforms_into CCO:B0041156 ! LIS1_HUMAN-Phosphotyrosine225 [Term] id: CCO:B0001619 name: DCC_HUMAN def: "Netrin receptor DCC precursor" [UniProtKB:P43146] synonym: "Colorectal cancer suppressor" EXACT [UniProtKB:P43146] synonym: "Tumor suppressor protein DCC" EXACT [UniProtKB:P43146] xref: EMBL:AAA35751.1 xref: EMBL:AAA52174.1 xref: EMBL:AAA52175.1 xref: EMBL:AAA52176.1 xref: EMBL:AAA52177.1 xref: EMBL:AAA52178.1 xref: EMBL:AAA52179.1 xref: EMBL:AAA52180.1 xref: EMBL:AAA52181.1 xref: EMBL:CAA53735.1 xref: UniProtKB:P43146 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004443 ! DCC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0035997 ! DCC_HUMAN-Phosphoserine1073 relationship: transforms_into CCO:B0035998 ! DCC_HUMAN-Phosphothreonine1074 [Term] id: CCO:B0001620 name: MSH2_HUMAN def: "DNA mismatch repair protein Msh2" [UniProtKB:P43246] synonym: "MutS protein homolog 2" EXACT [UniProtKB:P43246] xref: EMBL:AAA18643.1 xref: EMBL:AAA61870.1 xref: EMBL:AAA76858.1 xref: EMBL:AAA82080.1 xref: EMBL:AAB59564.1 xref: EMBL:AAB59565.1 xref: EMBL:AAC27930.1 xref: EMBL:AAH21566.1 xref: EMBL:AAS99351.1 xref: UniProtKB:O75488 xref: UniProtKB:P43246 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005126 ! MSH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006361 ! ikbkg-msh2 physical interaction relationship: participates_in CCO:I0006720 ! msh2-msh6-1 physical interaction relationship: participates_in CCO:I0006748 ! brca1-trrap-2 physical interaction relationship: participates_in CCO:I0006749 ! brca1-trrap-3 physical interaction relationship: participates_in CCO:I0006887 ! brca1-trrap-6 physical interaction relationship: participates_in CCO:I0007028 ! msh2-msh3 physical interaction relationship: participates_in CCO:I0007029 ! msh3-msh2-1 physical interaction relationship: participates_in CCO:I0007030 ! msh2-msh6 physical interaction relationship: participates_in CCO:I0007031 ! msh6-msh2 physical interaction relationship: participates_in CCO:I0007032 ! msh2-msh2 physical interaction relationship: participates_in CCO:I0007033 ! msh3-msh2-2 physical interaction relationship: participates_in CCO:I0007034 ! msh6-msh2-1 physical interaction relationship: participates_in CCO:I0007035 ! msh3-msh2-3 physical interaction relationship: participates_in CCO:I0007455 ! brca1-trrap-1 physical interaction relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:I0007838 ! msh2-msh6-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0013014 ! MSH2_HUMAN-Phosphoserine860 [Term] id: CCO:B0001621 name: RAD52_HUMAN def: "DNA repair protein RAD52 homolog" [UniProtKB:P43351] xref: EMBL:AAA85793.1 xref: EMBL:AAA87554.1 xref: EMBL:AAB05203.1 xref: EMBL:AAS00097.1 xref: UniProtKB:P43351 xref: UniProtKB:Q13205 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005417 ! RAD52_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006032 ! wrn-rad52-9 colocalization relationship: participates_in CCO:I0007127 ! wrn-rad52-6 physical interaction relationship: participates_in CCO:I0007128 ! wrn-rad52-7 physical interaction relationship: participates_in CCO:I0007436 ! wrn-rad52-1 physical interaction relationship: participates_in CCO:I0007437 ! rad52-rad52-1 physical interaction relationship: participates_in CCO:I0007438 ! rad52-rad51-1 physical interaction relationship: participates_in CCO:I0007439 ! wrn-rad52-2 direct interaction relationship: participates_in CCO:I0007440 ! wrn-rad52-3 direct interaction relationship: participates_in CCO:I0007441 ! wrn-rad52-4 direct interaction relationship: participates_in CCO:I0007442 ! wrn-rad52-5 direct interaction relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: transforms_into CCO:B0013670 ! RAD52_HUMAN-Phosphothreonine318 [Term] id: CCO:B0001622 name: KI67_HUMAN def: "Antigen KI-67" [UniProtKB:P46013] xref: EMBL:CAA46519.1 xref: EMBL:CAA46520.1 xref: EMBL:CAA64388.1 xref: EMBL:CAH73169.1 xref: UniProtKB:P46013 xref: UniProtKB:Q5VWH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004940 ! MKI67_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0012530 ! KI67_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0012531 ! KI67_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0012532 ! KI67_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0012533 ! KI67_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0012534 ! KI67_HUMAN-Phosphothreonine328 relationship: transforms_into CCO:B0012535 ! KI67_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0012536 ! KI67_HUMAN-Phosphoserine374 relationship: transforms_into CCO:B0012537 ! KI67_HUMAN-Phosphothreonine543 relationship: transforms_into CCO:B0012538 ! KI67_HUMAN-Phosphoserine579 relationship: transforms_into CCO:B0012539 ! KI67_HUMAN-Phosphoserine584 relationship: transforms_into CCO:B0012540 ! KI67_HUMAN-Phosphoserine648 relationship: transforms_into CCO:B0012541 ! KI67_HUMAN-Phosphoserine1098 relationship: transforms_into CCO:B0012542 ! KI67_HUMAN-Phosphoserine1131 relationship: transforms_into CCO:B0012543 ! KI67_HUMAN-Phosphothreonine1139 relationship: transforms_into CCO:B0012544 ! KI67_HUMAN-Phosphothreonine1193 relationship: transforms_into CCO:B0012545 ! KI67_HUMAN-Phosphoserine1207 relationship: transforms_into CCO:B0012546 ! KI67_HUMAN-Phosphothreonine1233 relationship: transforms_into CCO:B0012547 ! KI67_HUMAN-Phosphoserine1253 relationship: transforms_into CCO:B0012548 ! KI67_HUMAN-Phosphothreonine1298 relationship: transforms_into CCO:B0012549 ! KI67_HUMAN-Phosphoserine1302 relationship: transforms_into CCO:B0012550 ! KI67_HUMAN-Phosphothreonine1327 relationship: transforms_into CCO:B0012551 ! KI67_HUMAN-Phosphothreonine1335 relationship: transforms_into CCO:B0012552 ! KI67_HUMAN-Phosphothreonine1355 relationship: transforms_into CCO:B0012553 ! KI67_HUMAN-Phosphoserine1375 relationship: transforms_into CCO:B0012554 ! KI67_HUMAN-Phosphoserine1376 relationship: transforms_into CCO:B0012555 ! KI67_HUMAN-Phosphothreonine1557 relationship: transforms_into CCO:B0012556 ! KI67_HUMAN-Phosphothreonine1569 relationship: transforms_into CCO:B0012557 ! KI67_HUMAN-Phosphoserine1618 relationship: transforms_into CCO:B0012558 ! KI67_HUMAN-Phosphoserine1629 relationship: transforms_into CCO:B0012559 ! KI67_HUMAN-Phosphoserine1636 relationship: transforms_into CCO:B0012560 ! KI67_HUMAN-Phosphoserine1679 relationship: transforms_into CCO:B0012561 ! KI67_HUMAN-Phosphoserine1740 relationship: transforms_into CCO:B0012562 ! KI67_HUMAN-Phosphothreonine1764 relationship: transforms_into CCO:B0012563 ! KI67_HUMAN-Phosphothreonine1801 relationship: transforms_into CCO:B0012564 ! KI67_HUMAN-Phosphoserine1815 relationship: transforms_into CCO:B0012565 ! KI67_HUMAN-Phosphoserine1861 relationship: transforms_into CCO:B0012566 ! KI67_HUMAN-Phosphothreonine1897 relationship: transforms_into CCO:B0012567 ! KI67_HUMAN-Phosphothreonine1923 relationship: transforms_into CCO:B0012568 ! KI67_HUMAN-Phosphoserine1937 relationship: transforms_into CCO:B0012569 ! KI67_HUMAN-Phosphoserine2002 relationship: transforms_into CCO:B0012570 ! KI67_HUMAN-Phosphothreonine2085 relationship: transforms_into CCO:B0012571 ! KI67_HUMAN-Phosphoserine2105 relationship: transforms_into CCO:B0012572 ! KI67_HUMAN-Phosphoserine2223 relationship: transforms_into CCO:B0012573 ! KI67_HUMAN-Phosphothreonine2231 relationship: transforms_into CCO:B0012574 ! KI67_HUMAN-Phosphothreonine2285 relationship: transforms_into CCO:B0012575 ! KI67_HUMAN-Phosphothreonine2305 relationship: transforms_into CCO:B0012576 ! KI67_HUMAN-Phosphothreonine2406 relationship: transforms_into CCO:B0012577 ! KI67_HUMAN-Phosphoserine2505 relationship: transforms_into CCO:B0012578 ! KI67_HUMAN-Phosphothreonine2508 relationship: transforms_into CCO:B0012579 ! KI67_HUMAN-Phosphoserine2528 relationship: transforms_into CCO:B0012580 ! KI67_HUMAN-Phosphoserine2708 relationship: transforms_into CCO:B0012581 ! KI67_HUMAN-Phosphoserine2827 relationship: transforms_into CCO:B0012582 ! KI67_HUMAN-Phosphoserine2828 relationship: transforms_into CCO:B0036010 ! KI67_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0067304 ! KI67_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0067305 ! KI67_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0067306 ! KI67_HUMAN-Phosphothreonine347 relationship: transforms_into CCO:B0067307 ! KI67_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0067308 ! KI67_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0067309 ! KI67_HUMAN-Phosphoserine538 relationship: transforms_into CCO:B0067310 ! KI67_HUMAN-Phosphothreonine761 relationship: transforms_into CCO:B0067311 ! KI67_HUMAN-Phosphoserine859 relationship: transforms_into CCO:B0067312 ! KI67_HUMAN-Phosphothreonine1017 relationship: transforms_into CCO:B0067313 ! KI67_HUMAN-Phosphothreonine1111 relationship: transforms_into CCO:B0067314 ! KI67_HUMAN-Phosphothreonine1176 relationship: transforms_into CCO:B0067315 ! KI67_HUMAN-Phosphothreonine1237 relationship: transforms_into CCO:B0067316 ! KI67_HUMAN-Phosphoserine1256 relationship: transforms_into CCO:B0067317 ! KI67_HUMAN-Phosphothreonine1261 relationship: transforms_into CCO:B0067318 ! KI67_HUMAN-Phosphothreonine1315 relationship: transforms_into CCO:B0067319 ! KI67_HUMAN-Phosphothreonine1383 relationship: transforms_into CCO:B0067320 ! KI67_HUMAN-Phosphothreonine1503 relationship: transforms_into CCO:B0067321 ! KI67_HUMAN-Phosphoserine1506 relationship: transforms_into CCO:B0067322 ! KI67_HUMAN-Phosphothreonine1540 relationship: transforms_into CCO:B0067323 ! KI67_HUMAN-Phosphoserine1546 relationship: transforms_into CCO:B0067324 ! KI67_HUMAN-Phosphotyrosine1552 relationship: transforms_into CCO:B0067325 ! KI67_HUMAN-Phosphothreonine1565 relationship: transforms_into CCO:B0067326 ! KI67_HUMAN-Phosphoserine1571 relationship: transforms_into CCO:B0067327 ! KI67_HUMAN-Phosphoserine1689 relationship: transforms_into CCO:B0067328 ! KI67_HUMAN-Phosphothreonine1719 relationship: transforms_into CCO:B0067329 ! KI67_HUMAN-Phosphoserine1721 relationship: transforms_into CCO:B0067330 ! KI67_HUMAN-Phosphoserine1726 relationship: transforms_into CCO:B0067331 ! KI67_HUMAN-Phosphothreonine1747 relationship: transforms_into CCO:B0067332 ! KI67_HUMAN-Phosphothreonine1784 relationship: transforms_into CCO:B0067333 ! KI67_HUMAN-Phosphothreonine1841 relationship: transforms_into CCO:B0067334 ! KI67_HUMAN-Phosphoserine1864 relationship: transforms_into CCO:B0067335 ! KI67_HUMAN-Phosphothreonine1869 relationship: transforms_into CCO:B0067336 ! KI67_HUMAN-Phosphothreonine2065 relationship: transforms_into CCO:B0067337 ! KI67_HUMAN-Phosphoserine2072 relationship: transforms_into CCO:B0067338 ! KI67_HUMAN-Phosphothreonine2113 relationship: transforms_into CCO:B0067339 ! KI67_HUMAN-Phosphoserine2135 relationship: transforms_into CCO:B0067340 ! KI67_HUMAN-Phosphothreonine2203 relationship: transforms_into CCO:B0067341 ! KI67_HUMAN-Phosphothreonine2211 relationship: transforms_into CCO:B0067342 ! KI67_HUMAN-Phosphoserine2239 relationship: transforms_into CCO:B0067343 ! KI67_HUMAN-Phosphoserine2299 relationship: transforms_into CCO:B0067344 ! KI67_HUMAN-Phosphothreonine2325 relationship: transforms_into CCO:B0067345 ! KI67_HUMAN-Phosphothreonine2328 relationship: transforms_into CCO:B0067346 ! KI67_HUMAN-Phosphothreonine2332 relationship: transforms_into CCO:B0067347 ! KI67_HUMAN-Phosphoserine2344 relationship: transforms_into CCO:B0067348 ! KI67_HUMAN-Phosphothreonine2352 relationship: transforms_into CCO:B0067349 ! KI67_HUMAN-Phosphoserine2355 relationship: transforms_into CCO:B0067350 ! KI67_HUMAN-Phosphothreonine2389 relationship: transforms_into CCO:B0067351 ! KI67_HUMAN-Phosphoserine2395 relationship: transforms_into CCO:B0067352 ! KI67_HUMAN-Phosphoserine2420 relationship: transforms_into CCO:B0067353 ! KI67_HUMAN-Phosphothreonine2426 relationship: transforms_into CCO:B0067354 ! KI67_HUMAN-Phosphothreonine2446 relationship: transforms_into CCO:B0067355 ! KI67_HUMAN-Phosphoserine2466 relationship: transforms_into CCO:B0067356 ! KI67_HUMAN-Phosphoserine2588 relationship: transforms_into CCO:B0067357 ! KI67_HUMAN-Phosphoserine3041 [Term] id: CCO:B0001623 name: NOL1_HUMAN def: "Putative RNA methyltransferase NOL1" [UniProtKB:P46087] synonym: "EC 2.1.1.-" EXACT [UniProtKB:P46087] synonym: "Proliferating-cell nucleolar antigen p120" EXACT [UniProtKB:P46087] synonym: "Proliferation-associated nucleolar protein p120" EXACT [UniProtKB:P46087] xref: EMBL:AAA36398.1 xref: EMBL:AAH00656.1 xref: EMBL:AAH65257.1 xref: EMBL:AAI28184.1 xref: EMBL:AAI28185.1 xref: EMBL:CAA39119.1 xref: UniProtKB:A1A4Z3 xref: UniProtKB:P46087 xref: UniProtKB:Q0P5S5 xref: UniProtKB:Q58F30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005205 ! NOL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006369 ! map3k1-nol1 physical interaction relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0013208 ! NOL1_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0013209 ! NOL1_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0013210 ! NOL1_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0013211 ! NOL1_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0013212 ! NOL1_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0013213 ! NOL1_HUMAN-Phosphothreonine140 relationship: transforms_into CCO:B0013214 ! NOL1_HUMAN-Phosphoserine150 relationship: transforms_into CCO:B0013215 ! NOL1_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0013216 ! NOL1_HUMAN-Phosphothreonine185 relationship: transforms_into CCO:B0013217 ! NOL1_HUMAN-Phosphothreonine195 relationship: transforms_into CCO:B0013218 ! NOL1_HUMAN-Phosphothreonine603 relationship: transforms_into CCO:B0013219 ! NOL1_HUMAN-Phosphoserine732 relationship: transforms_into CCO:B0013220 ! NOL1_HUMAN-Phosphoserine734 relationship: transforms_into CCO:B0068760 ! NOL1_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0068761 ! NOL1_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0068762 ! NOL1_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0068763 ! NOL1_HUMAN-Phosphothreonine739 relationship: transforms_into CCO:B0068764 ! NOL1_HUMAN-Phosphothreonine776 relationship: transforms_into CCO:B0068765 ! NOL1_HUMAN-Phosphoserine786 relationship: transforms_into CCO:B0068766 ! NOL1_HUMAN-Phosphoserine812 [Term] id: CCO:B0001624 name: CDN1B_HUMAN def: "Cyclin-dependent kinase inhibitor 1B" [UniProtKB:P46527] synonym: "Cyclin-dependent kinase inhibitor p27" EXACT [UniProtKB:P46527] synonym: "p27Kip1" EXACT [UniProtKB:P46527] xref: EMBL:AAA20240.1 xref: EMBL:AAD14244.1 xref: EMBL:AAH01971.1 xref: EMBL:AAL78041.1 xref: UniProtKB:P46527 xref: UniProtKB:Q16307 xref: UniProtKB:Q9BUS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004310 ! CDKN1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005887 ! ccnd2-cdkn1b physical interaction relationship: participates_in CCO:I0005898 ! cdkn1b-traf2 physical interaction relationship: participates_in CCO:I0005944 ! ccnd3-cdkn1b physical interaction relationship: participates_in CCO:I0005984 ! cdn1b-cdk2-1 physical interaction relationship: participates_in CCO:I0005985 ! cdn1b-cdk2-2 physical interaction relationship: participates_in CCO:I0006058 ! cdknib-cdk4 physical interaction relationship: participates_in CCO:I0006059 ! cdknib-cdk2 physical interaction relationship: participates_in CCO:I0006262 ! src-cdn1b-1 phosphorylation relationship: participates_in CCO:I0006263 ! yes-cdn1b-1 phosphorylation relationship: participates_in CCO:I0006291 ! cdkn1b-ccne1-1 physical interaction relationship: participates_in CCO:I0006292 ! cdkn1b-ccnb1-1 physical interaction relationship: participates_in CCO:I0006461 ! cops5-cdkn1b physical interaction relationship: participates_in CCO:I0006462 ! cdkn1b-uchl1 physical interaction relationship: participates_in CCO:I0006826 ! ccne1-cdkn1b-1 physical interaction relationship: participates_in CCO:I0006827 ! ccnd1-cdkn1b-2 physical interaction relationship: participates_in CCO:I0006944 ! cdkn1b-lyn-2 phosphorylation relationship: participates_in CCO:I0006945 ! cdkn1b-abl-2 phosphorylation relationship: participates_in CCO:I0007044 ! cdn1b-cops5 colocalization relationship: participates_in CCO:I0007045 ! cdn1b-uchl1 colocalization relationship: participates_in CCO:I0007057 ! cdkn1b-cdk2-2 physical interaction relationship: participates_in CCO:I0007058 ! cdkn1b-cdk2-3 direct interaction relationship: participates_in CCO:I0007059 ! cdkn1b-ccna1-1 direct interaction relationship: participates_in CCO:I0007092 ! cdkn1b-ccnd1-2 physical interaction relationship: participates_in CCO:I0007253 ! trx-jab1-cdn1b physical interaction relationship: participates_in CCO:I0007323 ! cdkn1b-cdk2-4 physical interaction relationship: participates_in CCO:I0007481 ! cdn1b-cdk2-3 physical interaction relationship: participates_in CCO:I0007484 ! cdn1b-cdk2-4 physical interaction relationship: participates_in CCO:I0007485 ! cdn1b-cdk2-5 physical interaction relationship: participates_in CCO:I0007486 ! cdkn1b-lyn-1 physical interaction relationship: participates_in CCO:I0007487 ! cdkn1b-cdk2-1 physical interaction relationship: participates_in CCO:I0007488 ! cdkn1b-cdk2-5 phosphorylation relationship: participates_in CCO:I0007547 ! cdk4-cdkn1b-1 physical interaction relationship: participates_in CCO:I0007556 ! cdn1b-kpna3-1 physical interaction relationship: participates_in CCO:I0007557 ! cdn1b-kpna3-2 physical interaction relationship: participates_in CCO:I0007558 ! cdn1b-kpna5-1 physical interaction relationship: participates_in CCO:I0007559 ! cdn1b-kpna5-2 physical interaction relationship: participates_in CCO:I0007560 ! cdn1b-kpna5-3 physical interaction relationship: participates_in CCO:I0007741 ! cdn1b-kpna5-4 physical interaction relationship: participates_in CCO:I0007742 ! cdn1b-ywhab-1 physical interaction relationship: participates_in CCO:I0007743 ! cdn1b-ywhae-1 physical interaction relationship: participates_in CCO:I0007744 ! cdn1b-ywhag-1 physical interaction relationship: participates_in CCO:I0007822 ! stmn1-cdkn1b physical interaction relationship: participates_in CCO:I0007825 ! ccna2-cdk2-1 physical interaction relationship: participates_in CCO:I0007861 ! cdn1b-kpna3-3 physical interaction relationship: participates_in CCO:I0007862 ! cdn1b-kpna5-5 physical interaction relationship: participates_in CCO:I0008356 ! arhgdia-cdkn1b physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: participates_in CCO:P0003072 ! negative regulation of cell motility relationship: transforms_into CCO:B0011126 ! CDN1B_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0011127 ! CDN1B_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0064230 ! CDN1B_HUMAN-Phosphotyrosine74 relationship: transforms_into CCO:B0064231 ! CDN1B_HUMAN-Phosphotyrosine88 relationship: transforms_into CCO:B0064232 ! CDN1B_HUMAN-Phosphotyrosine89 relationship: transforms_into CCO:B0064233 ! CDN1B_HUMAN-Phosphothreonine157 relationship: transforms_into CCO:B0064234 ! CDN1B_HUMAN-Phosphothreonine187 relationship: transforms_into CCO:B0064235 ! CDN1B_HUMAN-Phosphothreonine198 [Term] id: CCO:B0001625 name: PSMD8_HUMAN def: "26S proteasome non-ATPase regulatory subunit 8" [UniProtKB:P48556] synonym: "26S proteasome regulatory subunit S14" EXACT [UniProtKB:P48556] synonym: "p31" EXACT [UniProtKB:P48556] xref: EMBL:AAC62833.1 xref: EMBL:AAH01164.3 xref: EMBL:BAA07237.1 xref: UniProtKB:P48556 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005392 ! PSMD8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002079 ! proteasome regulatory particle relationship: participates_in CCO:I0006419 ! traf6-psmd8 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0001626 name: NASP_HUMAN def: "Nuclear autoantigenic sperm protein" [UniProtKB:P49321] synonym: "NASP" EXACT [UniProtKB:P49321] xref: EMBL:AAA36027.1 xref: EMBL:AAH03113.1 xref: EMBL:AAH10105.1 xref: EMBL:AAH11580.1 xref: EMBL:AAH53608.1 xref: EMBL:BAD96536.1 xref: EMBL:CAI22462.1 xref: UniProtKB:P49321 xref: UniProtKB:Q53GW5 xref: UniProtKB:Q5T625 xref: UniProtKB:Q96A69 xref: UniProtKB:Q9BTW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005156 ! NASP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005783 ! hist1h3a-nasp physical interaction relationship: participates_in CCO:I0005886 ! hist2h3c-nasp physical interaction relationship: participates_in CCO:I0008279 ! nasp-luc7l2 physical interaction relationship: participates_in CCO:I0008350 ! ulk2-nasp physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0013091 ! NASP_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0013092 ! NASP_HUMAN-Phosphothreonine228 relationship: transforms_into CCO:B0013093 ! NASP_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0013094 ! NASP_HUMAN-Phosphothreonine390 relationship: transforms_into CCO:B0013095 ! NASP_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0013096 ! NASP_HUMAN-Phosphoserine451 relationship: transforms_into CCO:B0013097 ! NASP_HUMAN-Phosphothreonine464 relationship: transforms_into CCO:B0013098 ! NASP_HUMAN-Phosphothreonine477 relationship: transforms_into CCO:B0013099 ! NASP_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0013100 ! NASP_HUMAN-Phosphoserine497 relationship: transforms_into CCO:B0013101 ! NASP_HUMAN-Phosphoserine503 relationship: transforms_into CCO:B0013102 ! NASP_HUMAN-Phosphoserine726 relationship: transforms_into CCO:B0068442 ! NASP_HUMAN-Phosphoserine408 relationship: transforms_into CCO:B0068443 ! NASP_HUMAN-Phosphothreonine683 [Term] id: CCO:B0001627 name: CDK8_HUMAN def: "Cell division protein kinase 8" [UniProtKB:P49336] synonym: "Cyclin-dependent kinase 8" EXACT [UniProtKB:P49336] synonym: "EC 2.7.11.22" EXACT [UniProtKB:P49336] synonym: "EC 2.7.11.23" EXACT [UniProtKB:P49336] synonym: "Mediator complex subunit CDK8" EXACT [UniProtKB:P49336] synonym: "Mediator of RNA polymerase II transcription subunit CDK8" EXACT [UniProtKB:P49336] synonym: "Protein kinase K35" EXACT [UniProtKB:P49336] xref: EMBL:AAH69634.1 xref: EMBL:AAI04493.1 xref: EMBL:AAI05951.1 xref: EMBL:AAI07602.1 xref: EMBL:CAA59754.1 xref: EMBL:CAH72300.1 xref: EMBL:CAI16960.1 xref: EMBL:EAX08386.1 xref: EMBL:EAX08387.1 xref: UniProtKB:P49336 xref: UniProtKB:Q5VUF3 xref: UniProtKB:Q6ISB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004305 ! CDK8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001846 ! RNA polymerase subunit kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0006700 ! cdk8-q9btt4 physical interaction relationship: participates_in CCO:I0006701 ! crsp7-cdk8-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001628 name: UB2R1_HUMAN def: "Ubiquitin-conjugating enzyme E2 R1" [UniProtKB:P49427] synonym: "E2-CDC34" EXACT [UniProtKB:P49427] synonym: "EC 6.3.2.19" EXACT [UniProtKB:P49427] synonym: "Ubiquitin-conjugating enzyme E2-32 kDa complementing" EXACT [UniProtKB:P49427] synonym: "Ubiquitin-protein ligase R1" EXACT [UniProtKB:P49427] xref: EMBL:AAC37534.1 xref: EMBL:AAH09850.1 xref: EMBL:AAH18143.1 xref: EMBL:AAH23979.1 xref: EMBL:AAP35305.1 xref: EMBL:AAT46688.1 xref: UniProtKB:P49427 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005853 ! CDC34_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007149 ! dusp1-skp2-3 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: transforms_into CCO:B0014563 ! UB2R1_HUMAN-Phosphoserine231 [Term] id: CCO:B0001629 name: CENPF_HUMAN def: "Centromere protein F" [UniProtKB:P49454] synonym: "AH antigen" EXACT [UniProtKB:P49454] synonym: "Kinetochore protein CENP-F" EXACT [UniProtKB:P49454] synonym: "Mitosin" EXACT [UniProtKB:P49454] xref: EMBL:AAA82889.1 xref: EMBL:AAA82935.1 xref: EMBL:AAA86889.1 xref: EMBL:CAH71810.1 xref: EMBL:CAH73032.1 xref: UniProtKB:P49454 xref: UniProtKB:Q13171 xref: UniProtKB:Q13246 xref: UniProtKB:Q5VVM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004325 ! CENPF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:P0000015 ! G2 phase of mitotic cell cycle relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: participates_in CCO:P0000038 ! mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000105 ! mitotic cell cycle spindle assembly checkpoint relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0003077 ! cell division relationship: participates_in CCO:P0003080 ! metaphase plate congression relationship: transforms_into CCO:B0011155 ! CENPF_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0011156 ! CENPF_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0011157 ! CENPF_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0011158 ! CENPF_HUMAN-Phosphoserine821 relationship: transforms_into CCO:B0011159 ! CENPF_HUMAN-Phosphoserine1255 relationship: transforms_into CCO:B0011160 ! CENPF_HUMAN-Phosphoserine1282 relationship: transforms_into CCO:B0011161 ! CENPF_HUMAN-Phosphotyrosine1315 relationship: transforms_into CCO:B0011162 ! CENPF_HUMAN-Phosphothreonine1319 relationship: transforms_into CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: transforms_into CCO:B0011164 ! CENPF_HUMAN-Phosphoserine1747 relationship: transforms_into CCO:B0011165 ! CENPF_HUMAN-Phosphoserine1750 relationship: transforms_into CCO:B0011166 ! CENPF_HUMAN-Phosphoserine1988 relationship: transforms_into CCO:B0011167 ! CENPF_HUMAN-Phosphoserine2513 relationship: transforms_into CCO:B0011168 ! CENPF_HUMAN-Phosphoserine2638 relationship: transforms_into CCO:B0011169 ! CENPF_HUMAN-Phosphoserine2996 relationship: transforms_into CCO:B0011170 ! CENPF_HUMAN-Phosphoserine3007 relationship: transforms_into CCO:B0011171 ! CENPF_HUMAN-Phosphoserine3094 relationship: transforms_into CCO:B0011172 ! CENPF_HUMAN-Phosphoserine3119 relationship: transforms_into CCO:B0011173 ! CENPF_HUMAN-Phosphoserine3150 relationship: transforms_into CCO:B0011174 ! CENPF_HUMAN-Phosphoserine3175 relationship: transforms_into CCO:B0011175 ! CENPF_HUMAN-Phosphoserine3179 relationship: transforms_into CCO:B0064280 ! CENPF_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0064281 ! CENPF_HUMAN-Phosphothreonine144 relationship: transforms_into CCO:B0064282 ! CENPF_HUMAN-Phosphoserine834 relationship: transforms_into CCO:B0064283 ! CENPF_HUMAN-Phosphoserine1248 relationship: transforms_into CCO:B0064284 ! CENPF_HUMAN-Phosphoserine1748 relationship: transforms_into CCO:B0064285 ! CENPF_HUMAN-Phosphoserine2512 relationship: transforms_into CCO:B0064286 ! CENPF_HUMAN-Phosphoserine3122 [Term] id: CCO:B0001630 name: CTCF_HUMAN def: "Transcriptional repressor CTCF" [UniProtKB:P49711] synonym: "11-zinc finger protein" EXACT [UniProtKB:P49711] synonym: "CCCTC-binding factor" EXACT [UniProtKB:P49711] synonym: "CTCFL paralog" EXACT [UniProtKB:P49711] xref: EMBL:AAB07788.1 xref: EMBL:AAF31318.1 xref: EMBL:AAH14267.1 xref: UniProtKB:P49711 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004414 ! CTCF_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005977 ! hspb9-ctcf physical interaction relationship: participates_in CCO:I0006247 ! ctcf-chd8-5 colocalization relationship: participates_in CCO:I0006781 ! ctcf-chd8-3 physical interaction relationship: participates_in CCO:I0006782 ! ctcf-chd8-4 colocalization relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000654 ! genetic imprinting relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000918 ! maintenance of DNA methylation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011364 ! CTCF_HUMAN-Phosphoserine609 relationship: transforms_into CCO:B0011365 ! CTCF_HUMAN-Phosphoserine610 relationship: transforms_into CCO:B0011366 ! CTCF_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0064570 ! CTCF_HUMAN-Phosphothreonine374 relationship: transforms_into CCO:B0064571 ! CTCF_HUMAN-Phosphoserine402 [Term] id: CCO:B0001631 name: MCM2_HUMAN def: "DNA replication licensing factor MCM2" [UniProtKB:P49736] synonym: "Minichromosome maintenance protein 2 homolog" EXACT [UniProtKB:P49736] synonym: "Nuclear protein BM28" EXACT [UniProtKB:P49736] xref: EMBL:AAH06165.3 xref: EMBL:AAH07670.2 xref: EMBL:AAH07938.2 xref: EMBL:AAH14272.2 xref: EMBL:AAH17258.2 xref: EMBL:AAH17490.2 xref: EMBL:AAH30131.2 xref: EMBL:AAP88736.1 xref: EMBL:AAT70723.1 xref: EMBL:BAA04642.1 xref: EMBL:BAA12177.1 xref: EMBL:CAA47749.1 xref: UniProtKB:P49736 xref: UniProtKB:Q14577 xref: UniProtKB:Q15023 xref: UniProtKB:Q8N2V1 xref: UniProtKB:Q969W7 xref: UniProtKB:Q96AE1 xref: UniProtKB:Q9BRM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005037 ! MCM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005949 ! mcm2-mcm6 physical interaction relationship: participates_in CCO:I0006074 ! mcm2-orc6l direct interaction relationship: participates_in CCO:I0006078 ! mcm2-mcm3 direct interaction relationship: participates_in CCO:I0006083 ! mcm10-mcm2 direct interaction relationship: participates_in CCO:I0006084 ! mcm2-orc2l direct interaction relationship: participates_in CCO:I0006086 ! mcm2-mcm5 direct interaction relationship: participates_in CCO:I0006089 ! mcm2-cdk6 direct interaction relationship: participates_in CCO:I0006102 ! mcm2-ccnb2 direct interaction relationship: participates_in CCO:I0006108 ! mcm2-mcm7 direct interaction relationship: participates_in CCO:I0006110 ! mcm2-orc5l direct interaction relationship: participates_in CCO:I0006111 ! mcm2-hscdc6 direct interaction relationship: participates_in CCO:I0006130 ! mcm2-cdk4 direct interaction relationship: participates_in CCO:I0006142 ! mcm2-cdkn2a direct interaction relationship: participates_in CCO:I0006856 ! plk1-mcm2-1 physical interaction relationship: participates_in CCO:I0007914 ! mcm2-7_human physical interaction relationship: participates_in CCO:I0008109 ! gnb5-mcm2 physical interaction relationship: participates_in CCO:I0008152 ! prei3-mcm2 physical interaction relationship: participates_in CCO:I0008264 ! mcm2-rps4x physical interaction relationship: participates_in CCO:I0008275 ! mpp3-mcm2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012805 ! MCM2_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0012806 ! MCM2_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0012807 ! MCM2_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0012808 ! MCM2_HUMAN-Phosphothreonine39 relationship: transforms_into CCO:B0012809 ! MCM2_HUMAN-Phosphoserine40 relationship: transforms_into CCO:B0012810 ! MCM2_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0012811 ! MCM2_HUMAN-Phosphothreonine106 relationship: transforms_into CCO:B0012812 ! MCM2_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0012813 ! MCM2_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0032850 ! MCM2_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0048316 ! MCM2_HUMAN-Phosphothreonine25 relationship: transforms_into CCO:B0068062 ! MCM2_HUMAN-Phosphoserine381 [Term] id: CCO:B0001632 name: CLK1_HUMAN def: "Dual specificity protein kinase CLK1" [UniProtKB:P49759] synonym: "CDC-like kinase 1" EXACT [UniProtKB:P49759] synonym: "EC 2.7.12.1" EXACT [UniProtKB:P49759] xref: EMBL:AAA61480.1 xref: EMBL:AAB59459.1 xref: EMBL:AAH31549.1 xref: EMBL:AAY14722.1 xref: EMBL:EAW70217.1 xref: UniProtKB:P49759 xref: UniProtKB:Q8N5V8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004371 ! CLK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006180 ! clk1-pias4 physical interaction relationship: participates_in CCO:I0008478 ! golph2-clk1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011265 ! CLK1_HUMAN-Phosphothreonine138 relationship: transforms_into CCO:B0011266 ! CLK1_HUMAN-Phosphoserine140 [Term] id: CCO:B0001633 name: PLGF_HUMAN def: "Placenta growth factor precursor" [UniProtKB:P49763] synonym: "PlGF" EXACT [UniProtKB:P49763] xref: EMBL:AAB25832.2 xref: EMBL:AAB30462.2 xref: EMBL:AAD30179.1 xref: EMBL:AAH01422.1 xref: EMBL:AAH07255.1 xref: EMBL:AAH07789.1 xref: EMBL:CAA38698.1 xref: UniProtKB:P49763 xref: UniProtKB:Q07101 xref: UniProtKB:Q9BV78 xref: UniProtKB:Q9Y6S8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005336 ! PGF_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007470 ! flt1-pgf-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001634 name: VEGFB_HUMAN def: "Vascular endothelial growth factor B precursor" [UniProtKB:P49765] synonym: "VEGF-B" EXACT [UniProtKB:P49765] synonym: "VEGF-related factor" EXACT [UniProtKB:P49765] synonym: "VRF" EXACT [UniProtKB:P49765] xref: EMBL:AAA91462.1 xref: EMBL:AAA91463.1 xref: EMBL:AAB06274.1 xref: EMBL:AAC50721.1 xref: EMBL:AAH08818.1 xref: UniProtKB:P49765 xref: UniProtKB:Q16528 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005898 ! VEGFB_human relationship: has_function CCO:F0001473 ! vascular endothelial growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001635 name: VEGFC_HUMAN def: "Vascular endothelial growth factor C precursor" [UniProtKB:P49767] synonym: "Flt4 ligand" EXACT [UniProtKB:P49767] synonym: "Flt4-L" EXACT [UniProtKB:P49767] synonym: "Vascular endothelial growth factor-related protein" EXACT [UniProtKB:P49767] synonym: "VEGF-C" EXACT [UniProtKB:P49767] synonym: "VRP" EXACT [UniProtKB:P49767] xref: EMBL:AAA85214.1 xref: EMBL:AAB02909.1 xref: EMBL:AAH35212.1 xref: EMBL:AAH63685.1 xref: EMBL:CAA63907.1 xref: UniProtKB:P49767 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005899 ! VEGFC_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005815 ! vascular endothelial growth factor receptor 3 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000524 ! positive regulation of neuroblast proliferation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:B0001636 name: FHIT_HUMAN def: "Bis(5'-adenosyl)-triphosphatase" [UniProtKB:P49789] synonym: "AP3A hydrolase" EXACT [UniProtKB:P49789] synonym: "AP3Aase" EXACT [UniProtKB:P49789] synonym: "Diadenosine 5',5'''-P1,P3-triphosphate hydrolase" EXACT [UniProtKB:P49789] synonym: "Dinucleosidetriphosphatase" EXACT [UniProtKB:P49789] synonym: "EC 3.6.1.29" EXACT [UniProtKB:P49789] synonym: "Fragile histidine triad protein" EXACT [UniProtKB:P49789] xref: EMBL:AAA99013.1 xref: EMBL:AAB52539.1 xref: EMBL:AAH32336.1 xref: EMBL:AAT37530.1 xref: UniProtKB:P49789 xref: UniProtKB:Q6IU12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004645 ! FHIT_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0007012 ! bis(5'-adenosyl)-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005738 ! fhit-fhit physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0011881 ! FHIT_HUMAN-Phosphotyrosine114 relationship: transforms_into CCO:B0011882 ! FHIT_HUMAN-Phosphotyrosine145 [Term] id: CCO:B0001637 name: TSC2_HUMAN def: "Tuberin" [UniProtKB:P49815] synonym: "Tuberous sclerosis 2 protein" EXACT [UniProtKB:P49815] xref: EMBL:AAB41564.1 xref: EMBL:AAC34210.1 xref: EMBL:AAH25364.1 xref: EMBL:AAH46929.1 xref: EMBL:BAA32694.1 xref: EMBL:CAA53287.1 xref: UniProtKB:O75275 xref: UniProtKB:P49815 xref: UniProtKB:Q8TAZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005840 ! TSC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007275 ! nek1-tsc2-1 physical interaction relationship: participates_in CCO:I0007277 ! nek1-tsc2-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001086 ! negative regulation of phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001243 ! regulation of endocytosis relationship: participates_in CCO:P0002225 ! protein kinase B signaling cascade relationship: participates_in CCO:P0002704 ! regulation of insulin receptor signaling pathway relationship: participates_in CCO:P0002755 ! insulin-like growth factor receptor signaling pathway relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: participates_in CCO:P0003159 ! negative regulation of protein kinase B signaling cascade relationship: transforms_into CCO:B0014542 ! TSC2_HUMAN-Phosphoserine981 relationship: transforms_into CCO:B0014543 ! TSC2_HUMAN-Phosphoserine1364 relationship: transforms_into CCO:B0014544 ! TSC2_HUMAN-Phosphoserine1387 relationship: transforms_into CCO:B0014545 ! TSC2_HUMAN-Phosphoserine1411 relationship: transforms_into CCO:B0014546 ! TSC2_HUMAN-Phosphoserine1418 relationship: transforms_into CCO:B0014547 ! TSC2_HUMAN-Phosphoserine1420 relationship: transforms_into CCO:B0014548 ! TSC2_HUMAN-Phosphoserine1798 relationship: transforms_into CCO:B0048417 ! TSC2_HUMAN-Phosphoserine1097 relationship: transforms_into CCO:B0048418 ! TSC2_HUMAN-Phosphoserine1155 relationship: transforms_into CCO:B0071597 ! TSC2_HUMAN-Phosphothreonine927 relationship: transforms_into CCO:B0071598 ! TSC2_HUMAN-Phosphoserine1132 relationship: transforms_into CCO:B0071599 ! TSC2_HUMAN-Phosphoserine1334 relationship: transforms_into CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: transforms_into CCO:B0071601 ! TSC2_HUMAN-Phosphoserine1338 relationship: transforms_into CCO:B0071602 ! TSC2_HUMAN-Phosphoserine1341 relationship: transforms_into CCO:B0071603 ! TSC2_HUMAN-Phosphoserine1449 relationship: transforms_into CCO:B0071604 ! TSC2_HUMAN-Phosphoserine1452 [Term] id: CCO:B0001638 name: DNLI3_HUMAN def: "DNA ligase 3" [UniProtKB:P49916] synonym: "DNA ligase III" EXACT [UniProtKB:P49916] synonym: "EC 6.5.1.1" EXACT [UniProtKB:P49916] synonym: "Polydeoxyribonucleotide synthase [ATP] 3" EXACT [UniProtKB:P49916] xref: EMBL:AAA85022.1 xref: EMBL:AAL91592.1 xref: EMBL:CAA59230.1 xref: UniProtKB:P49916 xref: UniProtKB:Q16714 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004493 ! LIG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0064811 ! DNLI3_HUMAN-Phosphothreonine122 relationship: transforms_into CCO:B0064812 ! DNLI3_HUMAN-Phosphoserine123 relationship: transforms_into CCO:B0064813 ! DNLI3_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0064814 ! DNLI3_HUMAN-Phosphoserine155 [Term] id: CCO:B0001639 name: DNLI4_HUMAN def: "DNA ligase 4" [UniProtKB:P49917] synonym: "DNA ligase IV" EXACT [UniProtKB:P49917] synonym: "EC 6.5.1.1" EXACT [UniProtKB:P49917] synonym: "Polydeoxyribonucleotide synthase [ATP] 4" EXACT [UniProtKB:P49917] xref: EMBL:AAH37491.1 xref: EMBL:AAL77435.1 xref: EMBL:CAA58467.1 xref: EMBL:CAH70629.1 xref: UniProtKB:P49917 xref: UniProtKB:Q8IY66 xref: UniProtKB:Q8TEU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004494 ! LIG4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006771 ! lig4-xrcc4-1 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001981 ! somatic stem cell maintenance relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: participates_in CCO:P0002947 ! positive regulation of neurogenesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0064815 ! DNLI4_HUMAN-Phosphothreonine347 [Term] id: CCO:B0001640 name: CDN1C_HUMAN def: "Cyclin-dependent kinase inhibitor 1C" [UniProtKB:P49918] synonym: "Cyclin-dependent kinase inhibitor p57" EXACT [UniProtKB:P49918] synonym: "p57KIP2" EXACT [UniProtKB:P49918] xref: EMBL:AAA85095.1 xref: EMBL:AAB05896.1 xref: EMBL:AAH67842.1 xref: EMBL:BAA11014.1 xref: EMBL:BAA11015.1 xref: UniProtKB:P49918 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004311 ! CDKN1C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007546 ! cdk4-cdkn1c-1 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001272 ! positive regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: transforms_into CCO:B0064236 ! CDN1C_HUMAN-Phosphoserine268 [Term] id: CCO:B0001641 name: MRE11_HUMAN def: "Double-strand break repair protein MRE11A" [UniProtKB:P49959] synonym: "MRE11 homolog 1" EXACT [UniProtKB:P49959] synonym: "MRE11 meiotic recombination 11 homolog A" EXACT [UniProtKB:P49959] xref: EMBL:AAC36249.1 xref: EMBL:AAC78721.1 xref: EMBL:AAD10197.1 xref: EMBL:AAH63458.1 xref: EMBL:AAK18790.1 xref: EMBL:AAS79320.1 xref: UniProtKB:O43475 xref: UniProtKB:P49959 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005124 ! MRE11A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006202 ! ccne1-mre11a-1 physical interaction relationship: participates_in CCO:I0006516 ! nbs1-mre11a-1 physical interaction relationship: participates_in CCO:I0006517 ! h2afx-mre11a-2 physical interaction relationship: participates_in CCO:I0006960 ! mdc1-atm-1 physical interaction relationship: participates_in CCO:I0007271 ! nek1-mre11-1 physical interaction relationship: participates_in CCO:I0007850 ! h2afx-mre11a-1 colocalization relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000399 ! regulation of mitotic recombination relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: transforms_into CCO:B0013010 ! MRE11_HUMAN-Phosphothreonine74 relationship: transforms_into CCO:B0013011 ! MRE11_HUMAN-Phosphoserine678 relationship: transforms_into CCO:B0013012 ! MRE11_HUMAN-Phosphoserine688 relationship: transforms_into CCO:B0013013 ! MRE11_HUMAN-Phosphoserine689 relationship: transforms_into CCO:B0068286 ! MRE11_HUMAN-Phosphoserine649 [Term] id: CCO:B0001642 name: ERF_HUMAN def: "ETS domain-containing transcription factor ERF" [UniProtKB:P50548] synonym: "Ets2 repressor factor" EXACT [UniProtKB:P50548] synonym: "PE-2" EXACT [UniProtKB:P50548] xref: EMBL:AAA86686.1 xref: EMBL:AAD11987.1 xref: EMBL:AAH22231.1 xref: EMBL:BAD92508.1 xref: EMBL:BAG36938.1 xref: EMBL:EAW57116.1 xref: UniProtKB:B2RAP1 xref: UniProtKB:P50548 xref: UniProtKB:Q59G38 xref: UniProtKB:Q9UPI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004582 ! ERF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011758 ! ERF_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0011759 ! ERF_HUMAN-Phosphoserine185 relationship: transforms_into CCO:B0011760 ! ERF_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0011761 ! ERF_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0011762 ! ERF_HUMAN-Phosphothreonine526 relationship: transforms_into CCO:B0011763 ! ERF_HUMAN-Phosphoserine531 relationship: transforms_into CCO:B0065122 ! ERF_HUMAN-Phosphothreonine3 relationship: transforms_into CCO:B0065123 ! ERF_HUMAN-Phosphothreonine7 relationship: transforms_into CCO:B0065124 ! ERF_HUMAN-Phosphotyrosine16 relationship: transforms_into CCO:B0065125 ! ERF_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0065126 ! ERF_HUMAN-Phosphothreonine148 relationship: transforms_into CCO:B0065127 ! ERF_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0065128 ! ERF_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0065129 ! ERF_HUMAN-Phosphoserine431 relationship: transforms_into CCO:B0065130 ! ERF_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0065131 ! ERF_HUMAN-Phosphothreonine441 relationship: transforms_into CCO:B0065132 ! ERF_HUMAN-Phosphoserine444 relationship: transforms_into CCO:B0065133 ! ERF_HUMAN-Phosphoserine548 [Term] id: CCO:B0001643 name: DYN2_HUMAN def: "Dynamin-2" [UniProtKB:P50570] synonym: "EC 3.6.5.5" EXACT [UniProtKB:P50570] xref: EMBL:AAA88025.1 xref: EMBL:AAD23604.1 xref: EMBL:AAH39596.1 xref: EMBL:AAH54501.1 xref: UniProtKB:P50570 xref: UniProtKB:Q5I0Y0 xref: UniProtKB:Q7Z5S3 xref: UniProtKB:Q9UPH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004528 ! DNM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006072 ! fnbp1-dnm2-2 physical interaction relationship: participates_in CCO:I0006491 ! mphosph6-dnm2 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0007329 ! hck-dnm2-1 physical interaction relationship: participates_in CCO:I0007506 ! fnbp1-dnm2-1 colocalization relationship: participates_in CCO:I0008383 ! dnm2-bat1 physical interaction relationship: participates_in CCO:I0008470 ! dnm2-eif3s6ip physical interaction relationship: participates_in CCO:I0008471 ! dnm2-pef1 physical interaction relationship: participates_in CCO:I0008472 ! dnm2-ppib physical interaction relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0011602 ! DYN2_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0011603 ! DYN2_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: transforms_into CCO:B0011605 ! DYN2_HUMAN-Phosphothreonine766 [Term] id: CCO:B0001644 name: CDK7_HUMAN def: "Cell division protein kinase 7" [UniProtKB:P50613] synonym: "39 kDa protein kinase" EXACT [UniProtKB:P50613] synonym: "CAK" EXACT [UniProtKB:P50613] synonym: "CAK1" EXACT [UniProtKB:P50613] synonym: "CDK-activating kinase" EXACT [UniProtKB:P50613] synonym: "EC 2.7.11.22" EXACT [UniProtKB:P50613] synonym: "EC 2.7.11.23" EXACT [UniProtKB:P50613] synonym: "P39 Mo15" EXACT [UniProtKB:P50613] synonym: "STK1" EXACT [UniProtKB:P50613] synonym: "TFIIH basal transcription factor complex kinase subunit" EXACT [UniProtKB:P50613] xref: EMBL:AAA36657.1 xref: EMBL:AAH00834.1 xref: EMBL:AAH05298.1 xref: EMBL:AAM77799.1 xref: EMBL:CAA54508.1 xref: EMBL:CAA54793.1 xref: EMBL:CAA55785.1 xref: EMBL:CAA73587.1 xref: UniProtKB:P50613 xref: UniProtKB:Q9BS60 xref: UniProtKB:Q9UE19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004304 ! CDK7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011118 ! CDK7_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0011119 ! CDK7_HUMAN-Phosphothreonine170 [Term] id: CCO:B0001645 name: KNTC1_HUMAN def: "Kinetochore-associated protein 1" [UniProtKB:P50748] synonym: "hRod" EXACT [UniProtKB:P50748] synonym: "HsROD" EXACT [UniProtKB:P50748] synonym: "Rod" EXACT [UniProtKB:P50748] synonym: "Rough deal homolog" EXACT [UniProtKB:P50748] xref: EMBL:BAA11483.2 xref: UniProtKB:P50748 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004955 ! KNTC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007819 ! zw10_zwilch_1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012613 ! KNTC1_HUMAN-Phosphoserine2098 [Term] id: CCO:B0001646 name: RASF2_HUMAN def: "Ras association domain-containing protein 2" [UniProtKB:P50749] xref: EMBL:AAI17119.1 xref: EMBL:AAI17121.1 xref: EMBL:AAN59975.1 xref: EMBL:AAN59977.1 xref: EMBL:BAA11485.2 xref: EMBL:BAD96370.1 xref: EMBL:BAF84147.1 xref: EMBL:CAC34362.1 xref: EMBL:CAH10522.1 xref: EMBL:EAX10445.1 xref: UniProtKB:A6NIX9 xref: UniProtKB:A8K5Z3 xref: UniProtKB:P50749 xref: UniProtKB:Q17S06 xref: UniProtKB:Q53HD0 xref: UniProtKB:Q6AHZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005430 ! RASSF2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007375 ! kras-rassf2-1 physical interaction relationship: participates_in CCO:I0007412 ! krs-rassf2-2 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0001647 name: CDK9_HUMAN def: "Cell division protein kinase 9" [UniProtKB:P50750] synonym: "C-2K" EXACT [UniProtKB:P50750] synonym: "Cell division cycle 2-like protein kinase 4" EXACT [UniProtKB:P50750] synonym: "Cyclin-dependent kinase 9" EXACT [UniProtKB:P50750] synonym: "EC 2.7.11.22" EXACT [UniProtKB:P50750] synonym: "EC 2.7.11.23" EXACT [UniProtKB:P50750] synonym: "Serine/threonine-protein kinase PITALRE" EXACT [UniProtKB:P50750] xref: EMBL:AAA35668.1 xref: EMBL:AAF72183.1 xref: EMBL:AAH01968.1 xref: EMBL:AAM54039.1 xref: EMBL:AAV38706.1 xref: EMBL:CAA56516.1 xref: EMBL:CAI39767.1 xref: EMBL:CAI39768.1 xref: UniProtKB:P50750 xref: UniProtKB:Q5JU24 xref: UniProtKB:Q5JU25 xref: UniProtKB:Q5U006 xref: UniProtKB:Q96TF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004306 ! CDK9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001846 ! RNA polymerase subunit kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003544 ! snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011120 ! CDK9_HUMAN-Phosphothreonine186 [Term] id: CCO:B0001648 name: TCPD_HUMAN def: "T-complex protein 1 subunit delta" [UniProtKB:P50991] synonym: "CCT-delta" EXACT [UniProtKB:P50991] synonym: "Stimulator of TAR RNA-binding" EXACT [UniProtKB:P50991] synonym: "TCP-1-delta" EXACT [UniProtKB:P50991] xref: EMBL:AAC50384.1 xref: EMBL:AAC96010.1 xref: EMBL:AAH14676.1 xref: EMBL:AAI06934.1 xref: EMBL:AAI06935.1 xref: EMBL:AAY24140.1 xref: UniProtKB:O14870 xref: UniProtKB:P50991 xref: UniProtKB:Q53QP9 xref: UniProtKB:Q96C51 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005751 ! CCT4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000400 ! chaperonin-containing T-complex relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0006371 ! map3k1-cct4 physical interaction relationship: participates_in CCO:I0006387 ! map3k3-cct4 physical interaction relationship: participates_in CCO:I0006412 ! tbk1-cct4 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction [Term] id: CCO:B0001649 name: BRCA2_HUMAN def: "Breast cancer type 2 susceptibility protein" [UniProtKB:P51587] synonym: "Fanconi anemia group D1 protein" EXACT [UniProtKB:P51587] xref: EMBL:AAB07223.1 xref: EMBL:AAQ97181.1 xref: EMBL:CAA64484.1 xref: EMBL:CAA97728.1 xref: EMBL:CAA98995.2 xref: UniProtKB:O00183 xref: UniProtKB:O15008 xref: UniProtKB:P51587 xref: UniProtKB:Q13879 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004187 ! BRCA2_human relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005782 ! gamma-tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000985 ! secretory granule relationship: located_in CCO:C0001583 ! BRCA2-MAGE-D1 complex relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0006002 ! rad51-brca2-1 physical interaction relationship: participates_in CCO:I0006281 ! fancd2-brca2-2 physical interaction relationship: participates_in CCO:I0006543 ! brca2-shfdg1-2 physical interaction relationship: participates_in CCO:I0006670 ! brca2-shfdg1-3 physical interaction relationship: participates_in CCO:I0006671 ! shfdg1-brca2-3 physical interaction relationship: participates_in CCO:I0006841 ! brca2-rad51-2 physical interaction relationship: participates_in CCO:I0006948 ! brca2-rad51-1 physical interaction relationship: participates_in CCO:I0007010 ! brca2-rad51-9 physical interaction relationship: participates_in CCO:I0007073 ! fancd2-brca2-1 physical interaction relationship: participates_in CCO:I0007133 ! brca2-shfdg1-1 physical interaction relationship: participates_in CCO:I0007151 ! brca2-rad51-8 physical interaction relationship: participates_in CCO:I0007723 ! brca2-rad51-4 physical interaction relationship: participates_in CCO:I0007925 ! brca2-rad51-5 physical interaction relationship: participates_in CCO:I0007926 ! brca2-rad51-6 direct interaction relationship: participates_in CCO:I0007927 ! brca2-rad51-7 physical interaction relationship: participates_in CCO:I0007947 ! brca2-rad51-3 physical interaction relationship: participates_in CCO:P0000101 ! regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000132 ! male meiosis I relationship: participates_in CCO:P0000212 ! cytokinesis during cell cycle relationship: participates_in CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: participates_in CCO:P0000300 ! centrosome duplication relationship: participates_in CCO:P0000477 ! inner cell mass cell proliferation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000683 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator relationship: participates_in CCO:P0001835 ! negative regulation of mammary gland epithelial cell proliferation relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis relationship: participates_in CCO:P0002848 ! replication fork protection relationship: transforms_into CCO:B0010859 ! BRCA2_HUMAN-Phosphoserine683 relationship: transforms_into CCO:B0010860 ! BRCA2_HUMAN-Phosphoserine755 [Term] id: CCO:B0001650 name: HCFC1_HUMAN def: "Host cell factor" [UniProtKB:P51610] synonym: "C1 factor" EXACT [UniProtKB:P51610] synonym: "CFF" EXACT [UniProtKB:P51610] synonym: "HCF" EXACT [UniProtKB:P51610] synonym: "HCF-1" EXACT [UniProtKB:P51610] synonym: "VCAF" EXACT [UniProtKB:P51610] synonym: "VP16 accessory protein" EXACT [UniProtKB:P51610] xref: EMBL:AAH63435.1 xref: EMBL:CAA55790.1 xref: UniProtKB:P51610 xref: UniProtKB:Q6P4G5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004782 ! HCFC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006030 ! hcfc1-many-4 physical interaction relationship: participates_in CCO:I0006302 ! hcfc1-hdac1-1 physical interaction relationship: participates_in CCO:I0006303 ! hcfc1-hdac2-1 physical interaction relationship: participates_in CCO:I0006304 ! hcfc1-sp1-1 physical interaction relationship: participates_in CCO:I0006305 ! mll-hcfc2-2 physical interaction relationship: participates_in CCO:I0006313 ! hcfc1-zbtb17-9 physical interaction relationship: participates_in CCO:I0006323 ! hcfc1-creb3-2 physical interaction relationship: participates_in CCO:I0006523 ! hcfc1-zbtb17-3 physical interaction relationship: participates_in CCO:I0006624 ! hcfc1-set1-1 physical interaction relationship: participates_in CCO:I0006625 ! hcfc1-ash2l-1 physical interaction relationship: participates_in CCO:I0006626 ! hcfc1-wdr5-1 physical interaction relationship: participates_in CCO:I0006868 ! hcfc1-gabp2b1-2 physical interaction relationship: participates_in CCO:I0006869 ! hcfc1-zbtb17-2 physical interaction relationship: participates_in CCO:I0006972 ! hcfc1-many-3 physical interaction relationship: participates_in CCO:I0006973 ! hcfc1-zf-1 physical interaction relationship: participates_in CCO:I0006974 ! hcfc1-zf-3 physical interaction relationship: participates_in CCO:I0007094 ! hcfc1-ogt-1 physical interaction relationship: participates_in CCO:I0007095 ! hcfc1-sin3a-1 physical interaction relationship: participates_in CCO:I0007096 ! hcfc1-sin3b-1 physical interaction relationship: participates_in CCO:I0007097 ! hcfc1-sds3-1 physical interaction relationship: participates_in CCO:I0007098 ! hcfc1-hcfc1-1 physical interaction relationship: participates_in CCO:I0007115 ! hcfc1-zbtb17-4 physical interaction relationship: participates_in CCO:I0007116 ! hcfc1-zbtb17-5 physical interaction relationship: participates_in CCO:I0007117 ! hcfc1-zbtb17-6 physical interaction relationship: participates_in CCO:I0007118 ! hcfc1-zbtb17-7 physical interaction relationship: participates_in CCO:I0007119 ! hcfc1-zbtb17-8 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007251 ! hcfc1-sin3a-2 physical interaction relationship: participates_in CCO:I0007261 ! hcfc1-gabp2-3 physical interaction relationship: participates_in CCO:I0007262 ! hcfc1-gabpa-1 physical interaction relationship: participates_in CCO:I0007263 ! hcfc1-gabp2-4 direct interaction relationship: participates_in CCO:I0007264 ! hcfc1-creb3-3 direct interaction relationship: participates_in CCO:I0007265 ! hcfc1-zf-6 direct interaction relationship: participates_in CCO:I0007266 ! hcfc1-creb3-4 direct interaction relationship: participates_in CCO:I0007267 ! hcfc1-zf-7 direct interaction relationship: participates_in CCO:I0007355 ! hcfc1-many-2 physical interaction relationship: participates_in CCO:I0007561 ! hcfc1-sin3a-3 physical interaction relationship: participates_in CCO:I0007562 ! hcfc1-ash2l-2 physical interaction relationship: participates_in CCO:I0007565 ! hcfc1-zbtb17-1 physical interaction relationship: participates_in CCO:I0007752 ! hcfc1-creb3-1 physical interaction relationship: participates_in CCO:I0007754 ! hcfc1-zf-4 physical interaction relationship: participates_in CCO:I0007755 ! hcfc1-zf-5 physical interaction relationship: participates_in CCO:I0007872 ! hcfc1-pou2f1-1 physical interaction relationship: participates_in CCO:I0007873 ! hcfc1-egr2-1 physical interaction relationship: participates_in CCO:I0007875 ! hcfc1-zf-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000247 ! positive regulation of cell cycle relationship: participates_in CCO:P0002176 ! regulation of protein complex assembly relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0012144 ! HCFC1_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0012145 ! HCFC1_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0012146 ! HCFC1_HUMAN-Phosphothreonine733 relationship: transforms_into CCO:B0012147 ! HCFC1_HUMAN-Phosphothreonine737 relationship: transforms_into CCO:B0012148 ! HCFC1_HUMAN-Phosphothreonine738 relationship: transforms_into CCO:B0012149 ! HCFC1_HUMAN-Phosphothreonine1491 relationship: transforms_into CCO:B0012150 ! HCFC1_HUMAN-Phosphoserine1507 relationship: transforms_into CCO:B0012151 ! HCFC1_HUMAN-Phosphoserine2007 relationship: transforms_into CCO:B0012152 ! HCFC1_HUMAN-Phosphoserine2008 relationship: transforms_into CCO:B0012153 ! HCFC1_HUMAN-Phosphoserine2020 relationship: transforms_into CCO:B0066767 ! HCFC1_HUMAN-Phosphoserine1205 [Term] id: CCO:B0001651 name: STA5B_HUMAN def: "Signal transducer and activator of transcription 5B" [UniProtKB:P51692] xref: EMBL:AAC50485.2 xref: EMBL:AAC50491.1 xref: EMBL:AAH65227.1 xref: EMBL:CAD19638.1 xref: UniProtKB:P51692 xref: UniProtKB:Q8WWS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005682 ! STAT5B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007046 ! nmi-stat5b-1 physical interaction relationship: participates_in CCO:I0007047 ! stat5b-nmi-2 physical interaction relationship: participates_in CCO:I0007048 ! nmi-stat5b-2 physical interaction relationship: participates_in CCO:I0007049 ! nmi-stat5b-3 physical interaction relationship: participates_in CCO:I0007184 ! stat5b-nmi-3 physical interaction relationship: participates_in CCO:I0007186 ! cbp-stat5b-1 physical interaction relationship: participates_in CCO:I0007515 ! stat5b-nmi-1 physical interaction relationship: participates_in CCO:I0007718 ! stat5b-nmi-4 physical interaction relationship: participates_in CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001141 ! regulation of steroid metabolic process relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001342 ! regulation of epithelial cell differentiation relationship: participates_in CCO:P0002043 ! positive regulation of activated T cell proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002393 ! positive regulation of B cell differentiation relationship: participates_in CCO:P0002461 ! negative regulation of erythrocyte differentiation relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0014237 ! STA5B_HUMAN-Phosphoserine193 relationship: transforms_into CCO:B0014238 ! STA5B_HUMAN-Phosphotyrosine699 [Term] id: CCO:B0001652 name: CCNH_HUMAN def: "Cyclin-H" [UniProtKB:P51946] synonym: "MO15-associated protein" EXACT [UniProtKB:P51946] synonym: "p34" EXACT [UniProtKB:P51946] synonym: "p37" EXACT [UniProtKB:P51946] xref: EMBL:AAA21361.1 xref: EMBL:AAA57006.1 xref: EMBL:AAH05280.1 xref: EMBL:AAH16705.1 xref: EMBL:AAH16823.1 xref: EMBL:AAH22351.1 xref: EMBL:AAL74271.1 xref: UniProtKB:P51946 xref: UniProtKB:Q8TBL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004256 ! CCNH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005734 ! ccnh-sssca1 physical interaction relationship: participates_in CCO:I0005799 ! ccnh-psma1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0010998 ! CCNH_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0010999 ! CCNH_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0011000 ! CCNH_HUMAN-Phosphothreonine315 relationship: transforms_into CCO:B0064116 ! CCNH_HUMAN-Phosphoserine322 [Term] id: CCO:B0001653 name: MAT1_HUMAN def: "CDK-activating kinase assembly factor MAT1" [UniProtKB:P51948] synonym: "CDK7/cyclin H assembly factor" EXACT [UniProtKB:P51948] synonym: "Cyclin G1-interacting protein" EXACT [UniProtKB:P51948] synonym: "Menage a trois" EXACT [UniProtKB:P51948] synonym: "p35" EXACT [UniProtKB:P51948] synonym: "p36" EXACT [UniProtKB:P51948] synonym: "RING finger protein 66" EXACT [UniProtKB:P51948] synonym: "RING finger protein MAT1" EXACT [UniProtKB:P51948] xref: EMBL:AAB05248.1 xref: EMBL:AAH00820.1 xref: EMBL:AAN47195.1 xref: EMBL:CAA61112.1 xref: EMBL:CAA63356.1 xref: UniProtKB:P51948 xref: UniProtKB:Q15817 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005030 ! MNAT1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0008268 ! mnat1-cops6 physical interaction relationship: participates_in CCO:I0008269 ! mnat1-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0008270 ! mnat1-eef1a1 physical interaction relationship: participates_in CCO:I0008271 ! mnat1-rif1 physical interaction relationship: participates_in CCO:I0008408 ! mnat1-hps6 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0001654 name: NEK2_HUMAN def: "Serine/threonine-protein kinase Nek2" [UniProtKB:P51955] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P51955] synonym: "HSPK 21" EXACT [UniProtKB:P51955] synonym: "NimA-like protein kinase 1" EXACT [UniProtKB:P51955] synonym: "NimA-related protein kinase 2" EXACT [UniProtKB:P51955] xref: EMBL:AAA19558.1 xref: EMBL:AAH43502.2 xref: EMBL:AAH52807.1 xref: EMBL:AAH65932.1 xref: EMBL:AAK92212.1 xref: EMBL:AAV38534.1 xref: EMBL:BAD97073.1 xref: EMBL:CAA80912.1 xref: EMBL:CAA82309.1 xref: EMBL:CAH72901.1 xref: UniProtKB:P51955 xref: UniProtKB:Q53FD6 xref: UniProtKB:Q5VXZ1 xref: UniProtKB:Q6NZX8 xref: UniProtKB:Q7Z634 xref: UniProtKB:Q86XH2 xref: UniProtKB:Q96QN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005176 ! NEK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006730 ! nek2-nek11-6 physical interaction relationship: participates_in CCO:I0006870 ! nek2-nek11-2 colocalization relationship: participates_in CCO:I0006871 ! nek2-nek11-5 physical interaction relationship: participates_in CCO:I0006975 ! nek2-nek11-1 colocalization relationship: participates_in CCO:I0006976 ! nek2-nek11-7 phosphorylation relationship: participates_in CCO:I0007814 ! cdc27-nek2-1 physical interaction relationship: participates_in CCO:I0007929 ! cdc27-nek2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013148 ! NEK2_HUMAN-Phosphothreonine175 relationship: transforms_into CCO:B0031348 ! NEK2_HUMAN-Phosphothreonine170 relationship: transforms_into CCO:B0031349 ! NEK2_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0031350 ! NEK2_HUMAN-Phosphothreonine179 relationship: transforms_into CCO:B0031351 ! NEK2_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0031352 ! NEK2_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0031353 ! NEK2_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0031354 ! NEK2_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0031355 ! NEK2_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0031356 ! NEK2_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0031357 ! NEK2_HUMAN-Phosphoserine428 [Term] id: CCO:B0001655 name: NEK4_HUMAN def: "Serine/threonine-protein kinase Nek4" [UniProtKB:P51957] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P51957] synonym: "NimA-related protein kinase 4" EXACT [UniProtKB:P51957] synonym: "Serine/threonine-protein kinase 2" EXACT [UniProtKB:P51957] synonym: "Serine/threonine-protein kinase NRK2" EXACT [UniProtKB:P51957] xref: EMBL:AAA36658.1 xref: UniProtKB:P51957 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005177 ! NEK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013149 ! NEK4_HUMAN-Phosphothreonine165 relationship: transforms_into CCO:B0013150 ! NEK4_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0068561 ! NEK4_HUMAN-Phosphoserine484 [Term] id: CCO:B0001656 name: CCNG1_HUMAN def: "Cyclin-G1" [UniProtKB:P51959] synonym: "Cyclin-G" EXACT [UniProtKB:P51959] xref: EMBL:AAB03903.1 xref: EMBL:AAC41977.1 xref: EMBL:AAC50688.1 xref: EMBL:AAH00196.1 xref: EMBL:AAH07093.1 xref: EMBL:AAP35798.1 xref: EMBL:AAV40836.1 xref: EMBL:BAA11353.1 xref: EMBL:BAA13007.1 xref: EMBL:CAA54821.1 xref: UniProtKB:P51959 xref: UniProtKB:Q15757 xref: UniProtKB:Q96L32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004254 ! CCNG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001657 name: IMA2_HUMAN def: "Importin subunit alpha-2" [UniProtKB:P52292] synonym: "Karyopherin subunit alpha-2" EXACT [UniProtKB:P52292] synonym: "RAG cohort protein 1" EXACT [UniProtKB:P52292] synonym: "SRP1-alpha" EXACT [UniProtKB:P52292] xref: EMBL:AAA65700.1 xref: EMBL:AAA69957.1 xref: EMBL:AAH05978.1 xref: EMBL:CAC83080.1 xref: UniProtKB:P52292 xref: UniProtKB:Q9BRU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004886 ! KPNA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006186 ! ok/sw_cl_16-kpna2 physical interaction relationship: participates_in CCO:I0006187 ! mageh1-kpna2 physical interaction relationship: participates_in CCO:I0006188 ! kiaa1377-kpna2 physical interaction relationship: participates_in CCO:I0006425 ! nfkbib-kpna2 physical interaction relationship: participates_in CCO:I0006438 ! relb-kpna2 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0007525 ! kpna2-brca1 physical interaction relationship: participates_in CCO:I0007840 ! kpna-bcra1 physical interaction relationship: participates_in CCO:I0007841 ! bcra1-kpna2 physical interaction relationship: participates_in CCO:P0000003 ! M phase specific microtubule process relationship: participates_in CCO:P0000015 ! G2 phase of mitotic cell cycle relationship: participates_in CCO:P0000398 ! regulation of DNA recombination relationship: transforms_into CCO:B0012375 ! IMA2_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0012376 ! IMA2_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0012377 ! IMA2_HUMAN-Phosphoserine490 relationship: transforms_into CCO:B0048285 ! IMA2_HUMAN-N-acetylserine2 [Term] id: CCO:B0001658 name: MP2K6_HUMAN def: "Dual specificity mitogen-activated protein kinase kinase 6" [UniProtKB:P52564] synonym: "EC 2.7.12.2" EXACT [UniProtKB:P52564] synonym: "MAP kinase kinase 6" EXACT [UniProtKB:P52564] synonym: "MAPK/ERK kinase 6" EXACT [UniProtKB:P52564] synonym: "MAPKK 6" EXACT [UniProtKB:P52564] synonym: "SAPKK3" EXACT [UniProtKB:P52564] xref: EMBL:AAB03705.1 xref: EMBL:AAB03708.1 xref: EMBL:AAB05035.1 xref: EMBL:AAC50388.1 xref: EMBL:AAC50389.1 xref: EMBL:AAH12009.1 xref: EMBL:BAA13496.1 xref: EMBL:CAA65532.1 xref: UniProtKB:P52564 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005114 ! MAP2K6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007408 ! map3k4-map2k61 physical interaction relationship: participates_in CCO:I0007530 ! map3k4-gadd45 physical interaction relationship: participates_in CCO:I0007531 ! map3k4-gadd45-2 physical interaction relationship: participates_in CCO:I0007532 ! map3k4-gadd45-3 physical interaction relationship: participates_in CCO:I0007867 ! pkn1-map2k6-2 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012976 ! MP2K6_HUMAN-O-acetylserine207 relationship: transforms_into CCO:B0012977 ! MP2K6_HUMAN-Phosphoserine207 relationship: transforms_into CCO:B0012978 ! MP2K6_HUMAN-O-acetylthreonine211 relationship: transforms_into CCO:B0012979 ! MP2K6_HUMAN-Phosphothreonine211 [Term] id: CCO:B0001659 name: KIF11_HUMAN def: "Kinesin-like protein KIF11" [UniProtKB:P52732] synonym: "Kinesin-like protein 1" EXACT [UniProtKB:P52732] synonym: "Kinesin-like spindle protein HKSP" EXACT [UniProtKB:P52732] synonym: "Kinesin-related motor protein Eg5" EXACT [UniProtKB:P52732] synonym: "Thyroid receptor-interacting protein 5" EXACT [UniProtKB:P52732] synonym: "TRIP-5" EXACT [UniProtKB:P52732] xref: EMBL:AAA86132.1 xref: EMBL:AAC41739.1 xref: EMBL:AAI26212.1 xref: EMBL:CAA59449.1 xref: EMBL:CAH72288.1 xref: EMBL:CAI13671.1 xref: UniProtKB:A0AV49 xref: UniProtKB:P52732 xref: UniProtKB:Q15716 xref: UniProtKB:Q5VWX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004941 ! KIF11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006358 ! ikbke-kif11 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000110 ! mitotic centrosome separation relationship: participates_in CCO:P0000302 ! spindle pole body organization and biogenesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012583 ! KIF11_HUMAN-Phosphothreonine458 relationship: transforms_into CCO:B0012584 ! KIF11_HUMAN-Phosphothreonine926 relationship: transforms_into CCO:B0012585 ! KIF11_HUMAN-Phosphoserine931 [Term] id: CCO:B0001660 name: RBM5_HUMAN def: "RNA-binding protein 5" [UniProtKB:P52756] synonym: "Protein G15" EXACT [UniProtKB:P52756] synonym: "Renal carcinoma antigen NY-REN-9" EXACT [UniProtKB:P52756] synonym: "RNA-binding motif protein 5" EXACT [UniProtKB:P52756] synonym: "Tumor suppressor LUCA15" EXACT [UniProtKB:P52756] xref: EMBL:AAA99715.1 xref: EMBL:AAB42216.1 xref: EMBL:AAD04159.1 xref: EMBL:AAF02422.2 xref: UniProtKB:P52756 xref: UniProtKB:Q93021 xref: UniProtKB:Q9BU14 xref: UniProtKB:Q9UKY8 xref: UniProtKB:Q9UL24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005448 ! RBM5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008156 ! rbm5-rif1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0013789 ! RBM5_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0013790 ! RBM5_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0013791 ! RBM5_HUMAN-Phosphoserine621 relationship: transforms_into CCO:B0013792 ! RBM5_HUMAN-Phosphoserine624 [Term] id: CCO:B0001662 name: PPP5_HUMAN def: "Serine/threonine-protein phosphatase 5" [UniProtKB:P53041] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P53041] synonym: "PP-T" EXACT [UniProtKB:P53041] synonym: "PP5" EXACT [UniProtKB:P53041] synonym: "PPT" EXACT [UniProtKB:P53041] synonym: "Protein phosphatase T" EXACT [UniProtKB:P53041] xref: EMBL:AAB60384.1 xref: EMBL:AAD22669.1 xref: EMBL:AAH01970.1 xref: EMBL:CAA61595.1 xref: EMBL:CAA63089.1 xref: UniProtKB:P53041 xref: UniProtKB:Q16722 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005369 ! PPP5C_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006803 ! disc1-ppp5c physical interaction relationship: participates_in CCO:I0008297 ! ppp5c-cse1l physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0001663 name: PLK1_HUMAN def: "Serine/threonine-protein kinase PLK1" [UniProtKB:P53350] synonym: "EC 2.7.11.21" EXACT [UniProtKB:P53350] synonym: "PLK-1" EXACT [UniProtKB:P53350] synonym: "Polo-like kinase 1" EXACT [UniProtKB:P53350] synonym: "Serine/threonine-protein kinase 13" EXACT [UniProtKB:P53350] synonym: "STPK13" EXACT [UniProtKB:P53350] xref: EMBL:AAA36659.1 xref: EMBL:AAA56634.1 xref: EMBL:AAB36946.1 xref: EMBL:AAH02369.1 xref: EMBL:AAH03002.1 xref: EMBL:AAH14846.1 xref: EMBL:CAA51837.1 xref: EMBL:CAA53536.1 xref: EMBL:CAA62260.1 xref: UniProtKB:P53350 xref: UniProtKB:Q15153 xref: UniProtKB:Q99746 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005337 ! PLK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006705 ! plk1-mcm7-3 physical interaction relationship: participates_in CCO:I0006855 ! plk1-mcm7-1 physical interaction relationship: participates_in CCO:I0006856 ! plk1-mcm2-1 physical interaction relationship: participates_in CCO:I0006955 ! plk1-mcm7-2 physical interaction relationship: participates_in CCO:I0006956 ! plk1-mcm3-1 physical interaction relationship: participates_in CCO:I0006957 ! plk1-mcm7-4 physical interaction relationship: participates_in CCO:I0006995 ! fbxo5-plk1 phosphorylation relationship: participates_in CCO:I0006996 ! fbxo5-plk1-1 phosphorylation relationship: participates_in CCO:I0007915 ! wee1-plk1 phosphorylation relationship: participates_in CCO:I0008100 ! dnajb9-plk1 physical interaction relationship: participates_in CCO:I0008207 ! c7orf20-plk1 physical interaction relationship: participates_in CCO:I0008263 ! maged1-plk1 physical interaction relationship: participates_in CCO:I0008308 ! recql5-plk1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013568 ! PLK1_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0013569 ! PLK1_HUMAN-Phosphothreonine210 relationship: transforms_into CCO:B0013570 ! PLK1_HUMAN-Phosphoserine269 relationship: transforms_into CCO:B0013571 ! PLK1_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0069417 ! PLK1_HUMAN-Phosphothreonine214 [Term] id: CCO:B0001664 name: FOSB_HUMAN def: "Protein fosB" [UniProtKB:P53539] synonym: "G0/G1 switch regulatory protein 3" EXACT [UniProtKB:P53539] xref: EMBL:AAB53946.1 xref: EMBL:AAH36724.1 xref: EMBL:AAW65374.1 xref: UniProtKB:P53539 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004652 ! FOSB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001665 name: MK12_HUMAN def: "Mitogen-activated protein kinase 12" [UniProtKB:P53778] synonym: "EC 2.7.11.24" EXACT [UniProtKB:P53778] synonym: "ERK-6" EXACT [UniProtKB:P53778] synonym: "ERK5" EXACT [UniProtKB:P53778] synonym: "Extracellular signal-regulated kinase 6" EXACT [UniProtKB:P53778] synonym: "MAP kinase p38 gamma" EXACT [UniProtKB:P53778] synonym: "Mitogen-activated protein kinase p38 gamma" EXACT [UniProtKB:P53778] synonym: "Stress-activated protein kinase 3" EXACT [UniProtKB:P53778] xref: EMBL:AAB40118.1 xref: EMBL:AAH15741.1 xref: EMBL:CAA55984.1 xref: EMBL:CAA71511.1 xref: EMBL:CAB51538.1 xref: UniProtKB:P53778 xref: UniProtKB:Q14260 xref: UniProtKB:Q99588 xref: UniProtKB:Q99672 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005095 ! MAPK12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007865 ! pkn1-mapk12-1 physical interaction relationship: participates_in CCO:I0007866 ! pkn1-mapk12-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0012956 ! MK12_HUMAN-Phosphotyrosine27 relationship: transforms_into CCO:B0012957 ! MK12_HUMAN-Phosphothreonine183 relationship: transforms_into CCO:B0012958 ! MK12_HUMAN-Phosphotyrosine185 [Term] id: CCO:B0001666 name: HRSL3_HUMAN def: "HRAS-like suppressor 3" [UniProtKB:P53816] synonym: "H-rev 107 protein homolog" EXACT [UniProtKB:P53816] synonym: "HREV107-3" EXACT [UniProtKB:P53816] synonym: "Renal carcinoma antigen NY-REN-65" EXACT [UniProtKB:P53816] xref: EMBL:AAH01387.1 xref: EMBL:AAI03808.1 xref: EMBL:AAL26892.1 xref: EMBL:BAB08108.1 xref: EMBL:CAA63423.1 xref: UniProtKB:P53816 xref: UniProtKB:Q3SYI3 xref: UniProtKB:Q9HDD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004828 ! HRASLS3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0005789 ! hrasls3-ubqln1 physical interaction relationship: participates_in CCO:I0006640 ! hrasls3-ubqln4 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001667 name: TERF1_HUMAN def: "Telomeric repeat-binding factor 1" [UniProtKB:P54274] synonym: "NIMA-interacting protein 2" EXACT [UniProtKB:P54274] synonym: "Telomeric protein Pin2/TRF1" EXACT [UniProtKB:P54274] synonym: "TTAGGG repeat-binding factor 1" EXACT [UniProtKB:P54274] xref: EMBL:AAB17975.1 xref: EMBL:AAB53363.1 xref: EMBL:AAB54036.1 xref: EMBL:AAB81137.1 xref: EMBL:ABV02580.1 xref: EMBL:CAA63768.1 xref: UniProtKB:A7XP29 xref: UniProtKB:P54274 xref: UniProtKB:Q15553 xref: UniProtKB:Q93029 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005760 ! TERF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005963 ! pin2_trf1-eb1-1 physical interaction relationship: participates_in CCO:I0006326 ! blm-terf1-6 direct interaction relationship: participates_in CCO:I0006879 ! blm-terf1-7 direct interaction relationship: participates_in CCO:I0006880 ! blm-terf1-8 direct interaction relationship: participates_in CCO:I0007458 ! eb1-pin2_trf1-1 physical interaction relationship: participates_in CCO:I0007697 ! atm-pin2_trf1-1 physical interaction relationship: participates_in CCO:I0007698 ! pin2_trf1-atm-2 physical interaction relationship: participates_in CCO:I0007893 ! pot1-terf2-1 physical interaction relationship: participates_in CCO:I0007894 ! tinf2-terf1-1 physical interaction relationship: participates_in CCO:I0008172 ! terf1-git1 physical interaction relationship: participates_in CCO:I0008173 ! terf1-pfn2 physical interaction relationship: participates_in CCO:I0008174 ! terf1-zhx1 physical interaction relationship: participates_in CCO:I0008337 ! terf1-utp14a physical interaction relationship: participates_in CCO:I0008338 ! terf1-tinf2 physical interaction relationship: participates_in CCO:I0008437 ! terf1-capns1 physical interaction relationship: participates_in CCO:I0008438 ! terf1-dlg5 physical interaction relationship: participates_in CCO:I0008439 ! terf1-sh3gl3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014332 ! TERF1_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0014333 ! TERF1_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0071339 ! TERF1_HUMAN-Phosphoserine434 relationship: transforms_into CCO:B0071340 ! TERF1_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0071341 ! TERF1_HUMAN-Phosphoserine437 [Term] id: CCO:B0001668 name: PMS1_HUMAN def: "PMS1 protein homolog 1" [UniProtKB:P54277] synonym: "DNA mismatch repair protein PMS1" EXACT [UniProtKB:P54277] xref: EMBL:AAA63922.1 xref: EMBL:AAO89079.1 xref: UniProtKB:P54277 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005345 ! PMS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000645 ! mismatch repair relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001669 name: PMS2_HUMAN def: "Mismatch repair endonuclease PMS2" [UniProtKB:P54278] synonym: "DNA mismatch repair protein PMS2" EXACT [UniProtKB:P54278] synonym: "EC 3.1.-.-" EXACT [UniProtKB:P54278] synonym: "PMS1 protein homolog 2" EXACT [UniProtKB:P54278] xref: EMBL:AAA50390.1 xref: EMBL:AAA63923.1 xref: EMBL:AAH93921.1 xref: EMBL:AAS00390.1 xref: EMBL:BAD89425.1 xref: EMBL:BAD89426.1 xref: EMBL:BAD89428.1 xref: UniProtKB:P54278 xref: UniProtKB:Q52LH6 xref: UniProtKB:Q5FBW9 xref: UniProtKB:Q5FBX1 xref: UniProtKB:Q5FBX2 xref: UniProtKB:Q75MR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005346 ! PMS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007475 ! pms2-mlh1 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0013585 ! PMS2_HUMAN-Phosphotyrosine181 relationship: transforms_into CCO:B0013586 ! PMS2_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0013587 ! PMS2_HUMAN-Phosphothreonine573 [Term] id: CCO:B0001670 name: HSP72_HUMAN def: "Heat shock-related 70 kDa protein 2" [UniProtKB:P54652] synonym: "Heat shock 70 kDa protein 2" EXACT [UniProtKB:P54652] xref: EMBL:AAA52698.1 xref: EMBL:AAC50076.1 xref: EMBL:AAD11466.1 xref: EMBL:AAH01752.1 xref: EMBL:AAH36107.1 xref: EMBL:AAP88817.1 xref: EMBL:ABE96830.1 xref: UniProtKB:P54652 xref: UniProtKB:Q15508 xref: UniProtKB:Q53XM3 xref: UniProtKB:Q9UE78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004836 ! HSPA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005756 ! hspa2-hspbp1 physical interaction relationship: participates_in CCO:I0006373 ! map3k3-hspa2 physical interaction relationship: participates_in CCO:I0006394 ! ripk2-hspa2 physical interaction relationship: participates_in CCO:I0006407 ! q9nyj8-hspa2 physical interaction relationship: participates_in CCO:I0006652 ! ewsr1-hspa2 physical interaction relationship: participates_in CCO:I0006653 ! hspbp1-hspa2 physical interaction relationship: participates_in CCO:I0006654 ! meox2-hspa2 physical interaction relationship: participates_in CCO:I0006663 ! hspa2-hspbp1-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:P0000131 ! male meiosis relationship: transforms_into CCO:B0066925 ! HSP72_HUMAN-Phosphotyrosine42 relationship: transforms_into CCO:B0066926 ! HSP72_HUMAN-Phosphotyrosine108 [Term] id: CCO:B0001671 name: BCAT1_HUMAN def: "Branched-chain-amino-acid aminotransferase, cytosolic" [UniProtKB:P54687] synonym: "BCAT(c)" EXACT [UniProtKB:P54687] synonym: "EC 2.6.1.42" EXACT [UniProtKB:P54687] synonym: "Protein ECA39" EXACT [UniProtKB:P54687] xref: EMBL:AAB08528.1 xref: EMBL:BAB71129.1 xref: UniProtKB:P54687 xref: UniProtKB:Q96MY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004148 ! BCAT1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000559 ! branched-chain-amino-acid transaminase activity relationship: has_function CCO:F0001944 ! transaminase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001672 name: GAS1_HUMAN def: "Growth arrest-specific protein 1 precursor" [UniProtKB:P54826] synonym: "GAS-1" EXACT [UniProtKB:P54826] xref: EMBL:AAA72368.1 xref: UniProtKB:P54826 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004682 ! GAS1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001959 ! anchored to plasma membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation [Term] id: CCO:B0001673 name: AIF1_HUMAN def: "Allograft inflammatory factor 1" [UniProtKB:P55008] synonym: "AIF-1" EXACT [UniProtKB:P55008] synonym: "Ionized calcium-binding adapter molecule 1" EXACT [UniProtKB:P55008] synonym: "Protein G1" EXACT [UniProtKB:P55008] xref: EMBL:AAA92457.1 xref: EMBL:AAB05003.1 xref: EMBL:AAD18087.1 xref: EMBL:AAH09474.1 xref: EMBL:BAA13088.1 xref: EMBL:BAB63392.1 xref: EMBL:CAA75062.1 xref: EMBL:CAI17694.1 xref: EMBL:CAI18308.1 xref: EMBL:CAI18495.1 xref: UniProtKB:P55008 xref: UniProtKB:Q9UKS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004039 ! AIF1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001674 name: FGF8_HUMAN def: "Fibroblast growth factor 8 precursor" [UniProtKB:P55075] synonym: "AIGF" EXACT [UniProtKB:P55075] synonym: "Androgen-induced growth factor" EXACT [UniProtKB:P55075] synonym: "FGF-8" EXACT [UniProtKB:P55075] synonym: "HBGF-8" EXACT [UniProtKB:P55075] synonym: "Heparin-binding growth factor 8" EXACT [UniProtKB:P55075] xref: EMBL:AAB03787.1 xref: EMBL:AAB17893.1 xref: EMBL:AAB17894.1 xref: EMBL:AAB34255.1 xref: EMBL:AAB40953.1 xref: EMBL:AAB40954.1 xref: EMBL:AAB40955.1 xref: EMBL:AAC50782.1 xref: EMBL:AAC50783.1 xref: EMBL:AAC50784.1 xref: EMBL:AAC50785.1 xref: EMBL:AAM55238.1 xref: EMBL:BAA22527.1 xref: EMBL:BAA28605.1 xref: UniProtKB:P55075 xref: UniProtKB:Q14915 xref: UniProtKB:Q15766 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004639 ! FGF8_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0001675 name: CDN2D_HUMAN def: "Cyclin-dependent kinase 4 inhibitor D" [UniProtKB:P55273] synonym: "p19-INK4d" EXACT [UniProtKB:P55273] xref: EMBL:AAA85436.1 xref: EMBL:AAB03772.1 xref: EMBL:AAB18139.1 xref: EMBL:AAC27450.1 xref: EMBL:AAD02320.1 xref: EMBL:AAH01822.1 xref: EMBL:AAM54045.1 xref: EMBL:CAG46955.1 xref: UniProtKB:P55273 xref: UniProtKB:Q13102 xref: UniProtKB:Q6FGE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004314 ! CDKN2D_human relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005779 ! cdk4-cdkn2d physical interaction relationship: participates_in CCO:I0005871 ! cdkn2d-tbc1d17 physical interaction relationship: participates_in CCO:I0006793 ! cdk6-cdkn2d-2 direct interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: transforms_into CCO:B0011128 ! CDN2D_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0001676 name: NH2L1_HUMAN def: "NHP2-like protein 1" [UniProtKB:P55769] synonym: "High mobility group-like nuclear protein 2 homolog 1" EXACT [UniProtKB:P55769] synonym: "hSNU13" EXACT [UniProtKB:P55769] synonym: "OTK27" EXACT [UniProtKB:P55769] synonym: "U4/U6.U5 tri-snRNP 15.5 kDa protein" EXACT [UniProtKB:P55769] xref: EMBL:AAC72945.1 xref: EMBL:AAF06959.1 xref: EMBL:AAH05358.1 xref: EMBL:AAH19282.1 xref: EMBL:BAA23363.1 xref: EMBL:CAB46207.1 xref: EMBL:CAG30417.1 xref: UniProtKB:P55769 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005193 ! NHP2L1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008026 ! nhp2l1-cdkn2c physical interaction relationship: participates_in CCO:I0008280 ! nhp2l1-g22p1 physical interaction relationship: participates_in CCO:I0008282 ! nhp2l1-pola2 physical interaction relationship: participates_in CCO:I0008283 ! nhp2l1-rif1 physical interaction relationship: transforms_into CCO:B0013173 ! NH2L1_HUMAN-N-acetylthreonine2 [Term] id: CCO:B0001677 name: MTCPA_HUMAN def: "Protein p8 MTCP-1" [UniProtKB:P56277] synonym: "Mature T-cell proliferation-1 type A" EXACT [UniProtKB:P56277] synonym: "MTCP-1 type A" EXACT [UniProtKB:P56277] synonym: "p8MTCP1" EXACT [UniProtKB:P56277] xref: EMBL:AAH02600.1 xref: EMBL:AAP35395.1 xref: EMBL:CAA80829.1 xref: UniProtKB:P56277 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005131 ! MTCP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0005790 ! ewsr1-mtcp1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001678 name: MTCPB_HUMAN def: "Protein p13 MTCP-1" [UniProtKB:P56278] synonym: "Mature T-cell proliferation-1 type B1" EXACT [UniProtKB:P56278] synonym: "MTCP-1 type B1" EXACT [UniProtKB:P56278] synonym: "P13MTCP1" EXACT [UniProtKB:P56278] xref: EMBL:CAA80828.1 xref: EMBL:CAI41656.1 xref: EMBL:EAW72642.1 xref: UniProtKB:P56278 xref: UniProtKB:Q5HYP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005131 ! MTCP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001679 name: HDAC4_HUMAN def: "Histone deacetylase 4" [UniProtKB:P56524] synonym: "EC 3.5.1.98" EXACT [UniProtKB:P56524] synonym: "HD4" EXACT [UniProtKB:P56524] xref: EMBL:AAD29046.1 xref: EMBL:BAA22957.2 xref: UniProtKB:P56524 xref: UniProtKB:Q9UND6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004789 ! HDAC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006823 ! brms1-hdac4 physical interaction relationship: participates_in CCO:I0007192 ! hdac4-brms1 physical interaction relationship: participates_in CCO:I0007582 ! bcl6-hdac4 physical interaction relationship: participates_in CCO:I0007583 ! hdac4-bcl6 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0012163 ! HDAC4_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0012164 ! HDAC4_HUMAN-Phosphoserine467 relationship: transforms_into CCO:B0012165 ! HDAC4_HUMAN-Phosphoserine632 relationship: transforms_into CCO:B0066774 ! HDAC4_HUMAN-Phosphoserine565 relationship: transforms_into CCO:B0066775 ! HDAC4_HUMAN-Phosphoserine633 [Term] id: CCO:B0001680 name: SN1L1_HUMAN def: "Serine/threonine-protein kinase SNF1-like kinase 1" [UniProtKB:P57059] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P57059] synonym: "Salt-inducible kinase 1" EXACT [UniProtKB:P57059] synonym: "Serine/threonine-protein kinase SNF1LK" EXACT [UniProtKB:P57059] synonym: "SIK-1" EXACT [UniProtKB:P57059] synonym: "SIK1" EXACT [UniProtKB:P57059] xref: EMBL:AAH38504.1 xref: EMBL:BAA95536.1 xref: EMBL:BAC85126.1 xref: EMBL:BAD74070.1 xref: UniProtKB:A6NC84 xref: UniProtKB:P57059 xref: UniProtKB:Q5R2V5 xref: UniProtKB:Q6ZNL8 xref: UniProtKB:Q86YJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005641 ! SNF1LK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006258 ! qsk-ywhaz-3 physical interaction relationship: participates_in CCO:I0007180 ! snf1lk-ywhaz-1 physical interaction relationship: participates_in CCO:I0007183 ! snf1lk-ywhaz-2 direct interaction relationship: participates_in CCO:I0007837 ! qsk-ywhaz-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000138 ! regulation of mitotic cell cycle relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002409 ! regulation of cell differentiation relationship: transforms_into CCO:B0014128 ! SN1L1_HUMAN-Phosphothreonine182 relationship: transforms_into CCO:B0014129 ! SN1L1_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0014130 ! SN1L1_HUMAN-Phosphothreonine460 relationship: transforms_into CCO:B0014131 ! SN1L1_HUMAN-Phosphothreonine479 relationship: transforms_into CCO:B0014132 ! SN1L1_HUMAN-Phosphoserine578 [Term] id: CCO:B0001681 name: SESN2_HUMAN def: "Sestrin-2" [UniProtKB:P58004] synonym: "Hi95" EXACT [UniProtKB:P58004] xref: EMBL:AAH13304.1 xref: EMBL:AAH33719.1 xref: EMBL:AAM92261.1 xref: EMBL:BAB55438.1 xref: EMBL:BAG38070.1 xref: EMBL:CAB66486.1 xref: EMBL:CAI19133.1 xref: EMBL:EAX07703.1 xref: UniProtKB:P58004 xref: UniProtKB:Q5T7D0 xref: UniProtKB:Q96SI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005594 ! SESN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001682 name: SESN3_HUMAN def: "Sestrin-3" [UniProtKB:P58005] xref: EMBL:AAH17296.1 xref: EMBL:BAC04754.1 xref: UniProtKB:P58005 xref: UniProtKB:Q96AD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005595 ! SESN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001683 name: PROK1_HUMAN def: "Prokineticin-1 precursor" [UniProtKB:P58294] synonym: "EG-VEGF" EXACT [UniProtKB:P58294] synonym: "Endocrine-gland-derived vascular endothelial growth factor" EXACT [UniProtKB:P58294] synonym: "Mambakine" EXACT [UniProtKB:P58294] xref: EMBL:AAK33111.1 xref: EMBL:AAK49918.1 xref: EMBL:AAQ89046.1 xref: EMBL:CAH71489.1 xref: EMBL:CAH74102.1 xref: EMBL:EAW56449.1 xref: UniProtKB:P58294 xref: UniProtKB:Q5VWD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005382 ! PROK1_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001684 name: MLF1_HUMAN def: "Myeloid leukemia factor 1" [UniProtKB:P58340] synonym: "Myelodysplasia-myeloid leukemia factor 1" EXACT [UniProtKB:P58340] xref: EMBL:AAA99997.1 xref: EMBL:AAH07045.1 xref: UniProtKB:P58340 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005099 ! MLF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005819 ! magea11-mlf1 physical interaction relationship: participates_in CCO:I0008407 ! mlf1-grik5 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001685 name: PTEN_HUMAN def: "Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN" [UniProtKB:P60484] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P60484] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P60484] synonym: "EC 3.1.3.67" EXACT [UniProtKB:P60484] synonym: "Mutated in multiple advanced cancers 1" EXACT [UniProtKB:P60484] synonym: "Phosphatase and tensin homolog" EXACT [UniProtKB:P60484] xref: EMBL:AAB66902.1 xref: EMBL:AAC08699.1 xref: EMBL:AAC51182.1 xref: EMBL:AAC51183.1 xref: EMBL:AAD13528.1 xref: EMBL:AAD38372.1 xref: EMBL:AAH05821.1 xref: EMBL:AAY57327.1 xref: EMBL:CAG29302.1 xref: UniProtKB:O00633 xref: UniProtKB:O02679 xref: UniProtKB:P60484 xref: UniProtKB:Q6ICT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005396 ! PTEN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006324 ! pten-mast3-3 phosphorylation relationship: participates_in CCO:I0007572 ! pten-mast3-2 physical interaction relationship: participates_in CCO:I0007757 ! pten-mast3-1 physical interaction relationship: participates_in CCO:I0008301 ! pten-ang physical interaction relationship: participates_in CCO:I0008302 ! pten-chgb physical interaction relationship: participates_in CCO:I0008303 ! pten-cops6 physical interaction relationship: participates_in CCO:I0008304 ! pten-hba1 physical interaction relationship: participates_in CCO:I0008422 ! pten-utp14a physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001482 ! regulation of protein stability relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0003156 ! negative regulation of focal adhesion formation relationship: participates_in CCO:P0003159 ! negative regulation of protein kinase B signaling cascade relationship: transforms_into CCO:B0013640 ! PTEN_HUMAN-Phosphothreonine366 relationship: transforms_into CCO:B0013641 ! PTEN_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0013642 ! PTEN_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0013643 ! PTEN_HUMAN-Phosphothreonine401 [Term] id: CCO:B0001686 name: CKS1_HUMAN def: "Cyclin-dependent kinases regulatory subunit 1" [UniProtKB:P61024] synonym: "CKS-1" EXACT [UniProtKB:P61024] xref: EMBL:AAH07751.1 xref: EMBL:AAH15629.1 xref: EMBL:AAH70319.1 xref: EMBL:AAH70320.1 xref: EMBL:AAK07518.1 xref: EMBL:AAK07553.1 xref: EMBL:AAP35860.1 xref: EMBL:CAA38702.1 xref: UniProtKB:P33551 xref: UniProtKB:P61024 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004364 ! CKS1B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006747 ! dusp1-skp2-2 physical interaction relationship: participates_in CCO:I0007731 ! skp2-cks1-1 physical interaction relationship: participates_in CCO:I0007732 ! skp2-cks1-2 physical interaction relationship: participates_in CCO:I0007733 ! skp2-cks1-4 physical interaction relationship: participates_in CCO:I0007846 ! skp2-cks1-3 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001687 name: TGFB2_HUMAN def: "Transforming growth factor beta-2 precursor" [UniProtKB:P61812] synonym: "BSC-1 cell growth inhibitor" EXACT [UniProtKB:P61812] synonym: "Cetermin" EXACT [UniProtKB:P61812] synonym: "G-TSF" EXACT [UniProtKB:P61812] synonym: "Glioblastoma-derived T-cell suppressor factor" EXACT [UniProtKB:P61812] synonym: "Polyergin" EXACT [UniProtKB:P61812] synonym: "TGF-beta-2" EXACT [UniProtKB:P61812] xref: EMBL:AAA50404.1 xref: EMBL:AAA50405.1 xref: EMBL:AAA61162.1 xref: EMBL:AAH96235.1 xref: EMBL:AAH99635.1 xref: EMBL:AAR05442.1 xref: EMBL:CAA68279.1 xref: UniProtKB:P08112 xref: UniProtKB:P61812 xref: UniProtKB:Q15579 xref: UniProtKB:Q15581 xref: UniProtKB:Q4VAV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005774 ! TGFB2_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001462 ! transforming growth factor beta receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: located_in CCO:C0001709 ! cell soma relationship: participates_in CCO:I0006334 ! tgfb2-bapp-5 physical interaction relationship: participates_in CCO:I0006986 ! tgfb2-bapp-2 physical interaction relationship: participates_in CCO:I0006987 ! tgfb2-bapp-3 physical interaction relationship: participates_in CCO:I0007448 ! tgfb2-bapp-1 physical interaction relationship: participates_in CCO:I0007585 ! tgfb2-bapp-4 physical interaction relationship: participates_in CCO:I0007784 ! tgfb1-tgfb2-bapp-2 physical interaction relationship: participates_in CCO:P0000247 ! positive regulation of cell cycle relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001254 ! positive regulation of cell growth relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis relationship: participates_in CCO:P0002772 ! somatic stem cell division relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: participates_in CCO:P0003152 ! positive regulation of cardioblast differentiation relationship: participates_in CCO:P0003231 ! cardiac muscle cell proliferation [Term] id: CCO:B0001688 name: PP1A_HUMAN def: "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit" [UniProtKB:P62136] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P62136] synonym: "PP-1A" EXACT [UniProtKB:P62136] xref: EMBL:AAA36475.1 xref: EMBL:AAA36508.1 xref: EMBL:AAH01888.1 xref: EMBL:AAH04482.1 xref: EMBL:AAH08010.1 xref: EMBL:AAP35275.1 xref: EMBL:CAA50197.1 xref: UniProtKB:P08129 xref: UniProtKB:P20653 xref: UniProtKB:P22802 xref: UniProtKB:P62136 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005356 ! PPP1CA_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006379 ! map3k3-ppp1ca physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041172 ! PP1A_HUMAN-Phosphothreonine320 relationship: transforms_into CCO:B0069448 ! PP1A_HUMAN-N-acetylserine2 [Term] id: CCO:B0001689 name: PP1B_HUMAN def: "Serine/threonine-protein phosphatase PP1-beta catalytic subunit" [UniProtKB:P62140] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P62140] synonym: "PP-1B" EXACT [UniProtKB:P62140] xref: EMBL:AAA85093.1 xref: EMBL:AAF01137.1 xref: EMBL:AAH02697.1 xref: EMBL:AAH12045.1 xref: EMBL:AAV38549.1 xref: EMBL:AAY24124.1 xref: EMBL:CAA56870.1 xref: EMBL:CAG47059.1 xref: EMBL:CAG47080.1 xref: UniProtKB:P37140 xref: UniProtKB:P62140 xref: UniProtKB:Q5U087 xref: UniProtKB:Q6FG45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005357 ! PPP1CB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006367 ! ikbkg-ppp1cb physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013594 ! PP1B_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013595 ! PP1B_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0013596 ! PP1B_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0069449 ! PP1B_HUMAN-Phosphotyrosine306 relationship: transforms_into CCO:B0069450 ! PP1B_HUMAN-Phosphothreonine316 [Term] id: CCO:B0001690 name: CALM_HUMAN def: "Calmodulin" [UniProtKB:P62158] synonym: "CaM" EXACT [UniProtKB:P62158] xref: EMBL:AAA35635.1 xref: EMBL:AAA35641.1 xref: EMBL:AAA51918.1 xref: EMBL:AAB60644.1 xref: EMBL:AAC83174.1 xref: EMBL:AAD45181.1 xref: EMBL:AAH00454.1 xref: EMBL:AAH03354.1 xref: EMBL:AAH05137.1 xref: EMBL:AAH06464.1 xref: EMBL:AAH08437.1 xref: EMBL:AAH08597.1 xref: EMBL:AAH11834.1 xref: EMBL:AAH17385.1 xref: EMBL:AAH18677.1 xref: EMBL:AAH26065.1 xref: EMBL:AAH47523.1 xref: EMBL:AAP35464.1 xref: EMBL:AAP35501.1 xref: EMBL:AAP88918.1 xref: EMBL:AAY24085.1 xref: EMBL:BAA08302.1 xref: EMBL:CAA36839.1 xref: EMBL:CAG46787.1 xref: EMBL:CAG46818.1 xref: UniProtKB:P02593 xref: UniProtKB:P62158 xref: UniProtKB:P70667 xref: UniProtKB:P99014 xref: UniProtKB:Q13942 xref: UniProtKB:Q53S29 xref: UniProtKB:Q61379 xref: UniProtKB:Q61380 xref: UniProtKB:Q96HK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004214 ! CALM1_human relationship: encoded_by CCO:G0004215 ! CALM2_human relationship: encoded_by CCO:G0004216 ! CALM3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005837 ! calm1-kiaa1683 physical interaction relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0006287 ! cam-cd95-1 physical interaction relationship: participates_in CCO:I0006288 ! cam-cd95pm physical interaction relationship: participates_in CCO:I0006932 ! cacna1c-cam-1 physical interaction relationship: participates_in CCO:I0006933 ! cacna1c-cam-2 physical interaction relationship: participates_in CCO:I0007138 ! calm physical interaction relationship: participates_in CCO:I0007344 ! cam-cd95 physical interaction relationship: participates_in CCO:I0007378 ! calm1-obscn-1 physical interaction relationship: participates_in CCO:I0007543 ! cam-cd95-2 physical interaction relationship: participates_in CCO:I0008366 ! calm1-mrpl20 physical interaction relationship: participates_in CCO:I0008367 ! calm1-myo6 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0010909 ! CALM_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0010910 ! CALM_HUMAN-Phosphothreonine45 relationship: transforms_into CCO:B0010911 ! CALM_HUMAN-Phosphotyrosine100 relationship: transforms_into CCO:B0010912 ! CALM_HUMAN-N6,N6,N6-trimethyllysine116 [Term] id: CCO:B0001691 name: RS4X_HUMAN def: "40S ribosomal protein S4, X isoform" [UniProtKB:P62701] synonym: "SCR10" EXACT [UniProtKB:P62701] synonym: "Single copy abundant mRNA protein" EXACT [UniProtKB:P62701] xref: EMBL:AAA36597.1 xref: EMBL:AAA63255.1 xref: EMBL:AAB96968.1 xref: EMBL:AAH00472.1 xref: EMBL:AAH71662.1 xref: EMBL:AAI00904.1 xref: EMBL:AAI00905.1 xref: EMBL:CAA94808.1 xref: EMBL:CAG33016.1 xref: UniProtKB:P12631 xref: UniProtKB:P12750 xref: UniProtKB:P27576 xref: UniProtKB:P55831 xref: UniProtKB:P62701 xref: UniProtKB:Q14727 xref: UniProtKB:Q6IPY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005537 ! RPS4X_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0006370 ! map3k1-rps4x physical interaction relationship: participates_in CCO:I0006388 ! nfkb2-rps4x physical interaction relationship: participates_in CCO:I0006391 ! map3k14-rps4x physical interaction relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0008264 ! mcm2-rps4x physical interaction relationship: participates_in CCO:I0008398 ! hnrph3-rps4x physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001692 name: RHOB_HUMAN def: "Rho-related GTP-binding protein RhoB precursor" [UniProtKB:P62745] synonym: "H6" EXACT [UniProtKB:P62745] xref: EMBL:AAA36565.1 xref: EMBL:AAH66954.1 xref: EMBL:AAM21118.1 xref: EMBL:AAV38353.1 xref: EMBL:AAV38354.1 xref: EMBL:AAY24345.1 xref: EMBL:CAA29968.1 xref: EMBL:CAG47068.1 xref: EMBL:DAA01138.1 xref: EMBL:DAA01912.1 xref: UniProtKB:P01121 xref: UniProtKB:P62745 xref: UniProtKB:Q5U0H6 xref: UniProtKB:Q7RTN5 xref: UniProtKB:Q7RTR9 xref: UniProtKB:Q9CUV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005484 ! RHOB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0013856 ! RHOB_HUMAN-ADP-ribosylasparagine41 relationship: transforms_into CCO:B0013857 ! RHOB_HUMAN-Cysteine methyl ester193 relationship: transforms_into CCO:B0031371 ! RHOB_HUMAN-Phosphotyrosine154 [Term] id: CCO:B0001693 name: RAN_HUMAN def: "GTP-binding nuclear protein Ran" [UniProtKB:P62826] synonym: "Androgen receptor-associated protein 24" EXACT [UniProtKB:P62826] synonym: "GTPase Ran" EXACT [UniProtKB:P62826] synonym: "Ras-like protein TC4" EXACT [UniProtKB:P62826] synonym: "Ras-related nuclear protein" EXACT [UniProtKB:P62826] xref: EMBL:AAA36546.1 xref: EMBL:AAC05840.1 xref: EMBL:AAC99400.1 xref: EMBL:AAH04272.3 xref: EMBL:AAH14518.1 xref: EMBL:AAH14901.1 xref: EMBL:AAH16654.1 xref: EMBL:AAH51908.2 xref: EMBL:AAH72000.1 xref: EMBL:AAM15923.1 xref: EMBL:AAP35935.1 xref: EMBL:BAB93486.1 xref: EMBL:CAG29343.1 xref: UniProtKB:P17080 xref: UniProtKB:P28746 xref: UniProtKB:P28747 xref: UniProtKB:P62826 xref: UniProtKB:Q6IPB2 xref: UniProtKB:Q86V08 xref: UniProtKB:Q8NI90 xref: UniProtKB:Q9CSP3 xref: UniProtKB:Q9CWI7 xref: UniProtKB:Q9CZA2 xref: UniProtKB:Q9UDJ5 xref: UniProtKB:Q9UEU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005425 ! RAN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006776 ! ran-ranbp1-1 physical interaction relationship: participates_in CCO:I0006777 ! ran-ranbp1-2 physical interaction relationship: participates_in CCO:I0006829 ! ran-xpot-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007153 ! ranbp3-ran-1 physical interaction relationship: participates_in CCO:I0007310 ! ran-tnpo1-1 direct interaction relationship: participates_in CCO:I0007471 ! ran-rcc1-1 direct interaction relationship: participates_in CCO:I0007861 ! cdn1b-kpna3-3 physical interaction relationship: participates_in CCO:I0007862 ! cdn1b-kpna5-5 physical interaction relationship: participates_in CCO:I0008307 ! ran-kiaa1377 physical interaction relationship: participates_in CCO:I0008494 ! ran-nefl physical interaction relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013708 ! RAN_HUMAN-Phosphotyrosine147 relationship: transforms_into CCO:B0069733 ! RAN_HUMAN-Phosphotyrosine155 [Term] id: CCO:B0001694 name: RAP1A_HUMAN def: "Ras-related protein Rap-1A precursor" [UniProtKB:P62834] synonym: "C21KG" EXACT [UniProtKB:P62834] synonym: "G-22K" EXACT [UniProtKB:P62834] synonym: "GTP-binding protein smg-p21A" EXACT [UniProtKB:P62834] synonym: "Ras-related protein Krev-1" EXACT [UniProtKB:P62834] xref: EMBL:AAA36150.1 xref: EMBL:AAH14086.1 xref: EMBL:AAM12626.1 xref: EMBL:CAA31051.1 xref: EMBL:CAB55685.2 xref: UniProtKB:P10113 xref: UniProtKB:P62834 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005426 ! RAP1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006916 ! raf1-rap1a-1 direct interaction relationship: participates_in CCO:I0007002 ! rap1a-itgal-1 physical interaction relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007163 ! raf1-rap1a-2 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0013709 ! RAP1A_HUMAN-Cysteine methyl ester181 [Term] id: CCO:B0001695 name: UBIQ_HUMAN def: "Ubiquitin" [UniProtKB:P62988] xref: EMBL:AAA36787.1 xref: EMBL:AAA36788.1 xref: EMBL:AAA36789.1 xref: EMBL:AAB21188.1 xref: EMBL:AAC25582.1 xref: EMBL:AAH00379.1 xref: EMBL:AAH09301.1 xref: EMBL:AAH15127.1 xref: EMBL:AAH26301.1 xref: EMBL:AAH31027.1 xref: EMBL:AAH39193.1 xref: EMBL:AAH46123.1 xref: EMBL:AAH66293.1 xref: EMBL:AAK31162.1 xref: EMBL:BAA09860.1 xref: EMBL:BAA23486.1 xref: EMBL:BAA23632.1 xref: EMBL:BAB79490.1 xref: EMBL:BAC56951.1 xref: EMBL:BAC56955.1 xref: EMBL:CAA28495.1 xref: EMBL:CAA40312.1 xref: EMBL:CAA40313.1 xref: EMBL:CAA40314.1 xref: EMBL:CAA44911.1 xref: UniProtKB:P02248 xref: UniProtKB:P02249 xref: UniProtKB:P02250 xref: UniProtKB:P62988 xref: UniProtKB:Q29120 xref: UniProtKB:Q6LBL4 xref: UniProtKB:Q6LDU5 xref: UniProtKB:Q8WYN8 xref: UniProtKB:Q91887 xref: UniProtKB:Q91888 xref: UniProtKB:Q9BWD6 xref: UniProtKB:Q9BX98 xref: UniProtKB:Q9UEF2 xref: UniProtKB:Q9UEG1 xref: UniProtKB:Q9UEK8 xref: UniProtKB:Q9UPK7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005863 ! RPS27A_human relationship: encoded_by CCO:G0005864 ! UBA52_human relationship: encoded_by CCO:G0005865 ! UBB_human relationship: encoded_by CCO:G0005866 ! UBC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006613 ! cdc6-ubiq-1 physical interaction relationship: participates_in CCO:I0006745 ! dusp1-ubiq-1 ubiquitination relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007149 ! dusp1-skp2-3 physical interaction relationship: participates_in CCO:I0007312 ! rps27a-tsg101-1 direct interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007848 ! orc1-rps27a-1 physical interaction relationship: participates_in CCO:I0008162 ! sfpq-rps27a physical interaction relationship: participates_in CCO:I0008163 ! rps27a-sfpq physical interaction relationship: transforms_into CCO:B0014565 ! UBIQ_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0014566 ! UBIQ_HUMAN-Phosphoserine65 [Term] id: CCO:B0001696 name: UBC9_HUMAN def: "SUMO-conjugating enzyme UBC9" [UniProtKB:P63279] synonym: "EC 6.3.2.-" EXACT [UniProtKB:P63279] synonym: "p18" EXACT [UniProtKB:P63279] synonym: "SUMO-protein ligase" EXACT [UniProtKB:P63279] synonym: "Ubiquitin carrier protein 9" EXACT [UniProtKB:P63279] synonym: "Ubiquitin carrier protein I" EXACT [UniProtKB:P63279] synonym: "Ubiquitin-conjugating enzyme E2 I" EXACT [UniProtKB:P63279] synonym: "Ubiquitin-protein ligase I" EXACT [UniProtKB:P63279] xref: EMBL:AAA86662.1 xref: EMBL:AAB02181.1 xref: EMBL:AAB09410.1 xref: EMBL:AAC50603.1 xref: EMBL:AAC50715.1 xref: EMBL:AAC50716.1 xref: EMBL:AAC51361.1 xref: EMBL:AAH00427.1 xref: EMBL:AAH04429.1 xref: EMBL:AAH51289.3 xref: EMBL:AAK61274.1 xref: EMBL:AAP35578.1 xref: EMBL:BAA08091.1 xref: EMBL:BAD92225.1 xref: EMBL:CAA05359.1 xref: EMBL:CAA65287.1 xref: EMBL:CAB45853.1 xref: UniProtKB:P50550 xref: UniProtKB:P63279 xref: UniProtKB:Q15698 xref: UniProtKB:Q59GX1 xref: UniProtKB:Q86VB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005858 ! UBE2I_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_function CCO:F0005846 ! HLH domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000122 ! synaptonemal complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:I0005736 ! c14orf32-ube2i physical interaction relationship: participates_in CCO:I0005742 ! c18orf25-ube2i physical interaction relationship: participates_in CCO:I0005748 ! satb1-ube2i physical interaction relationship: participates_in CCO:I0005752 ! dach1-ube2i physical interaction relationship: participates_in CCO:I0005755 ! nudcd3-ube2i physical interaction relationship: participates_in CCO:I0005773 ! ube2i-znfn1a1 physical interaction relationship: participates_in CCO:I0005776 ! ripk2-ube2i physical interaction relationship: participates_in CCO:I0005788 ! pdlim7-ube2i physical interaction relationship: participates_in CCO:I0005795 ! ube2i-znf646 physical interaction relationship: participates_in CCO:I0005851 ! phc1-ube2i physical interaction relationship: participates_in CCO:I0005857 ! chmp4b-ube2i physical interaction relationship: participates_in CCO:I0005873 ! hgs-ube2i physical interaction relationship: participates_in CCO:I0005875 ! rad54b-ube2i physical interaction relationship: participates_in CCO:I0005876 ! ube2i-zbed1x physical interaction relationship: participates_in CCO:I0005901 ! trim29-ube2i physical interaction relationship: participates_in CCO:I0005920 ! hnrpc-ube2i physical interaction relationship: participates_in CCO:I0005928 ! ube2i-znf451 physical interaction relationship: participates_in CCO:I0005929 ! hnrpk-ube2i physical interaction relationship: participates_in CCO:I0005952 ! pias2-ube2i physical interaction relationship: participates_in CCO:I0005954 ! smad4-ube2i physical interaction relationship: participates_in CCO:I0006056 ! ap2g-ubc9-1 physical interaction relationship: participates_in CCO:I0006213 ! dnmt3b-ube2i-2 physical interaction relationship: participates_in CCO:I0006630 ! dnmt3b-ubl1-ube2i-1 physical interaction relationship: participates_in CCO:I0006789 ! uchl1-ube2i physical interaction relationship: participates_in CCO:I0006928 ! hnrpd-ube2i-2 physical interaction relationship: participates_in CCO:I0007173 ! dj_1-ubc9 physical interaction relationship: participates_in CCO:I0007287 ! dnmt3b-ube2i-1 physical interaction relationship: participates_in CCO:I0007316 ! bhlbh2-ube2i physical interaction relationship: participates_in CCO:I0007476 ! bhlbh2-ube2i-2 physical interaction relationship: participates_in CCO:I0007511 ! bhlbh2-ube2i-1 physical interaction relationship: participates_in CCO:I0007622 ! atxn1-ube2i physical interaction relationship: participates_in CCO:I0007823 ! hnrpd-ube2i physical interaction relationship: participates_in CCO:I0007918 ! ap2a-ubc9-1 physical interaction relationship: participates_in CCO:I0007919 ! ap2b-ubc9-1 physical interaction relationship: participates_in CCO:I0007920 ! ap2g-ubc9-2 physical interaction relationship: participates_in CCO:I0007921 ! ubc9-ap2a-1 physical interaction relationship: participates_in CCO:I0007922 ! ubc9-ap2b-1 physical interaction relationship: participates_in CCO:I0007923 ! ubc9-ap2g-1 physical interaction relationship: participates_in CCO:I0008184 ! ube2i-unc119 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001697 name: PP2AA_HUMAN def: "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform" [UniProtKB:P67775] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P67775] synonym: "PP2A-alpha" EXACT [UniProtKB:P67775] synonym: "Replication protein C" EXACT [UniProtKB:P67775] synonym: "RP-C" EXACT [UniProtKB:P67775] xref: EMBL:AAA36466.1 xref: EMBL:AAB38019.1 xref: EMBL:AAH00400.1 xref: EMBL:AAH02657.1 xref: EMBL:AAH19275.1 xref: EMBL:AAH31696.1 xref: EMBL:CAA31176.1 xref: UniProtKB:P05323 xref: UniProtKB:P13197 xref: UniProtKB:P67775 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005359 ! PPP2CA_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006758 ! sgol1-ppp2ca-1 physical interaction relationship: participates_in CCO:I0006761 ! sgol2-ppp2ca-1 physical interaction relationship: participates_in CCO:I0007181 ! snf1l2-2aab-1 physical interaction relationship: participates_in CCO:I0008034 ! ppp2ca-ptn physical interaction relationship: participates_in CCO:I0008411 ! mrps26-ppp2ca physical interaction relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000639 ! regulation of DNA replication relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0001148 ! second-messenger-mediated signaling relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002083 ! negative regulation of tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002409 ! regulation of cell differentiation relationship: transforms_into CCO:B0013597 ! PP2AA_HUMAN-Phosphotyrosine307 relationship: transforms_into CCO:B0013598 ! PP2AA_HUMAN-Leucine methyl ester309 [Term] id: CCO:B0001698 name: MORN_HUMAN def: "Morphogenetic neuropeptide" [UniProtKB:P69208] synonym: "HA" EXACT [UniProtKB:P69208] synonym: "Head activator" EXACT [UniProtKB:P69208] xref: UniProtKB:P01163 xref: UniProtKB:P69208 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012973 ! MORN_HUMAN-Pyrrolidone carboxylic acid1 [Term] id: CCO:B0001699 name: IF4G2_HUMAN def: "Eukaryotic translation initiation factor 4 gamma 2" [UniProtKB:P78344] synonym: "DAP-5" EXACT [UniProtKB:P78344] synonym: "Death-associated protein 5" EXACT [UniProtKB:P78344] synonym: "eIF-4-gamma 2" EXACT [UniProtKB:P78344] synonym: "eIF-4G 2" EXACT [UniProtKB:P78344] synonym: "eIF4G 2" EXACT [UniProtKB:P78344] synonym: "p97" EXACT [UniProtKB:P78344] xref: EMBL:AAB49973.1 xref: EMBL:AAC51166.1 xref: EMBL:AAH14930.2 xref: EMBL:AAH18975.1 xref: EMBL:AAH39851.1 xref: EMBL:AAI11416.1 xref: EMBL:BAB93515.1 xref: EMBL:BAD97268.1 xref: EMBL:CAA61857.1 xref: UniProtKB:O60877 xref: UniProtKB:P78344 xref: UniProtKB:P78404 xref: UniProtKB:Q0VH00 xref: UniProtKB:Q53EU1 xref: UniProtKB:Q58EZ2 xref: UniProtKB:Q8NI71 xref: UniProtKB:Q96C16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004864 ! EIF4G2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006888 ! eif4g2-eif4a1-1 direct interaction relationship: participates_in CCO:I0007328 ! eif4gii-eif4aii physical interaction relationship: participates_in CCO:I0007603 ! eif4g2-eif4a1-2 direct interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0012333 ! IF4G2_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0012334 ! IF4G2_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0012335 ! IF4G2_HUMAN-Phosphothreonine508 relationship: transforms_into CCO:B0067039 ! IF4G2_HUMAN-Phosphothreonine514 [Term] id: CCO:B0001700 name: TCPB_HUMAN def: "T-complex protein 1 subunit beta" [UniProtKB:P78371] synonym: "CCT-beta" EXACT [UniProtKB:P78371] synonym: "TCP-1-beta" EXACT [UniProtKB:P78371] xref: EMBL:AAB67249.1 xref: EMBL:AAC96012.1 xref: EMBL:AAC98906.1 xref: EMBL:AAI13515.1 xref: EMBL:AAI13517.1 xref: EMBL:AAV38769.1 xref: EMBL:CAG33352.1 xref: UniProtKB:P78371 xref: UniProtKB:Q14D36 xref: UniProtKB:Q6IAT3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005750 ! CCT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006384 ! map3k3-cct2 physical interaction relationship: participates_in CCO:I0006411 ! tbk1-cct2 physical interaction relationship: transforms_into CCO:B0014323 ! TCPB_HUMAN-N-acetylalanine2 [Term] id: CCO:B0001701 name: CCNA1_HUMAN def: "Cyclin-A1" [UniProtKB:P78396] xref: EMBL:AAB49754.1 xref: EMBL:AAB60863.1 xref: EMBL:AAH36346.1 xref: EMBL:AAV38384.1 xref: EMBL:CAI12728.1 xref: EMBL:EAX08565.1 xref: EMBL:EAX08566.1 xref: UniProtKB:P78396 xref: UniProtKB:Q5T3V0 xref: UniProtKB:Q5U0G2 xref: UniProtKB:Q8IY91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004242 ! CCNA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: participates_in CCO:I0006020 ! orc1-cdk2-1 physical interaction relationship: participates_in CCO:I0006021 ! orc1-orc2-1 physical interaction relationship: participates_in CCO:I0006114 ! mcm6-ccna1 direct interaction relationship: participates_in CCO:I0006156 ! cdkn1a-ccna1 direct interaction relationship: participates_in CCO:I0006157 ! mcm4-ccna1 direct interaction relationship: participates_in CCO:I0007533 ! cdt1-cdk2-1 physical interaction relationship: participates_in CCO:I0007855 ! cdkn1a-ccna1-1 physical interaction relationship: participates_in CCO:I0007895 ! cyclina1_cdk1_human direct interaction relationship: participates_in CCO:I0007897 ! cyclina1_cdk2_human direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000132 ! male meiosis I relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001702 name: TXN4A_HUMAN def: "Thioredoxin-like protein 4A" [UniProtKB:P83876] synonym: "DIM1 protein homolog" EXACT [UniProtKB:P83876] synonym: "Spliceosomal U5 snRNP-specific 15 kDa protein" EXACT [UniProtKB:P83876] synonym: "Thioredoxin-like U5 snRNP protein U5-15kD" EXACT [UniProtKB:P83876] xref: EMBL:AAB81950.1 xref: EMBL:AAF17332.1 xref: EMBL:AAH01046.1 xref: EMBL:AAH19272.1 xref: UniProtKB:O14834 xref: UniProtKB:P83876 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005847 ! TXNL4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005791 ! rhebl1-txnl4a physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0071634 ! TXN4A_HUMAN-Phosphoserine132 [Term] id: CCO:B0001703 name: ERH_HUMAN def: "Enhancer of rudimentary homolog" [UniProtKB:P84090] xref: EMBL:AAC51172.1 xref: EMBL:AAH14301.1 xref: EMBL:AAH71709.1 xref: EMBL:AAP35523.1 xref: EMBL:BAA12865.1 xref: EMBL:CAG29294.1 xref: EMBL:CAG46975.1 xref: UniProtKB:P70659 xref: UniProtKB:P84090 xref: UniProtKB:Q14259 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004584 ! ERH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007987 ! erh-tp53 physical interaction relationship: participates_in CCO:I0008011 ! erh-tle1 physical interaction relationship: participates_in CCO:I0008103 ! erh-med31 physical interaction relationship: participates_in CCO:I0008105 ! erh-setdb1 physical interaction relationship: participates_in CCO:I0008230 ! erh-sh3gl2 physical interaction relationship: transforms_into CCO:B0048255 ! ERH_HUMAN-N-acetylserine2 [Term] id: CCO:B0001704 name: RHOG_HUMAN def: "Rho-related GTP-binding protein RhoG precursor" [UniProtKB:P84095] xref: EMBL:AAA60268.1 xref: EMBL:AAM21121.1 xref: EMBL:AAS75333.1 xref: EMBL:CAA43784.1 xref: UniProtKB:P35238 xref: UniProtKB:P84095 xref: UniProtKB:Q8NI04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005485 ! RHOG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006852 ! rhog-elmo1-1 physical interaction relationship: participates_in CCO:I0007074 ! rhog-elmo1-3 physical interaction relationship: participates_in CCO:I0007238 ! rhog-elmo1-2 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0013858 ! RHOG_HUMAN-ADP-ribosylasparagine39 relationship: transforms_into CCO:B0013859 ! RHOG_HUMAN-Cysteine methyl ester188 [Term] id: CCO:B0001706 name: FOXO4_HUMAN def: "Forkhead box protein O4" [UniProtKB:P98177] synonym: "Fork head domain transcription factor AFX1" EXACT [UniProtKB:P98177] xref: EMBL:AAA82171.1 xref: EMBL:AAI06762.1 xref: EMBL:AAL85197.1 xref: EMBL:CAA63819.1 xref: EMBL:CAA72156.1 xref: UniProtKB:O43821 xref: UniProtKB:P98177 xref: UniProtKB:Q13720 xref: UniProtKB:Q3KPF1 xref: UniProtKB:Q8TDK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004656 ! FOXO4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0003048 ! negative regulation of smooth muscle cell differentiation relationship: transforms_into CCO:B0011890 ! FOXO4_HUMAN-Phosphothreonine32 relationship: transforms_into CCO:B0011891 ! FOXO4_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0011892 ! FOXO4_HUMAN-Phosphoserine262 relationship: transforms_into CCO:B0036005 ! FOXO4_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0036006 ! FOXO4_HUMAN-Phosphoserine200 [Term] id: CCO:B0001707 name: CDK3_HUMAN def: "Cell division protein kinase 3" [UniProtKB:Q00526] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q00526] xref: EMBL:AAV40830.1 xref: EMBL:CAA47001.1 xref: UniProtKB:Q00526 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004300 ! CDK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011107 ! CDK3_HUMAN-Phosphothreonine14 relationship: transforms_into CCO:B0011108 ! CDK3_HUMAN-Phosphotyrosine15 relationship: transforms_into CCO:B0011109 ! CDK3_HUMAN-Phosphotyrosine19 relationship: transforms_into CCO:B0011110 ! CDK3_HUMAN-Phosphothreonine160 relationship: transforms_into CCO:B0011111 ! CDK3_HUMAN-Phosphoserine207 relationship: transforms_into CCO:B0048192 ! CDK3_HUMAN-Phosphotyrosine159 [Term] id: CCO:B0001708 name: CDK6_HUMAN def: "Cell division protein kinase 6" [UniProtKB:Q00534] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q00534] synonym: "Serine/threonine-protein kinase PLSTIRE" EXACT [UniProtKB:Q00534] xref: EMBL:AAH52264.1 xref: EMBL:AAM76970.1 xref: EMBL:CAA47008.1 xref: UniProtKB:Q00534 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004303 ! CDK6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004391 ! cyclin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006089 ! mcm2-cdk6 direct interaction relationship: participates_in CCO:I0006112 ! cdk6-cdkn2a direct interaction relationship: participates_in CCO:I0006119 ! mcm10-cdk6 direct interaction relationship: participates_in CCO:I0006131 ! cdk6-ccnd3 direct interaction relationship: participates_in CCO:I0006143 ! cdk6-ccnd1 direct interaction relationship: participates_in CCO:I0006148 ! cdkn1a-cdk6 direct interaction relationship: participates_in CCO:I0006608 ! cdk6-cdc37-1 physical interaction relationship: participates_in CCO:I0006646 ! cdk6-atxn1 physical interaction relationship: participates_in CCO:I0006792 ! cdk6-cdkn2a-1 direct interaction relationship: participates_in CCO:I0006793 ! cdk6-cdkn2d-2 direct interaction relationship: participates_in CCO:I0007393 ! cdk6-cdc37 physical interaction relationship: participates_in CCO:I0007905 ! cyclind3_cdk6_human direct interaction relationship: participates_in CCO:I0007906 ! cyclind1_cdk6_human direct interaction relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000509 ! positive regulation of cell-matrix adhesion relationship: participates_in CCO:P0000947 ! regulation of gene expression relationship: participates_in CCO:P0002460 ! regulation of erythrocyte differentiation relationship: participates_in CCO:P0002482 ! negative regulation of osteoblast differentiation relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011116 ! CDK6_HUMAN-Phosphotyrosine13 relationship: transforms_into CCO:B0011117 ! CDK6_HUMAN-Phosphotyrosine24 [Term] id: CCO:B0001709 name: CDK5_HUMAN def: "Cell division protein kinase 5" [UniProtKB:Q00535] synonym: "Cyclin-dependent kinase 5" EXACT [UniProtKB:Q00535] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q00535] synonym: "Serine/threonine-protein kinase PSSALRE" EXACT [UniProtKB:Q00535] synonym: "Tau protein kinase II catalytic subunit" EXACT [UniProtKB:Q00535] synonym: "TPKII catalytic subunit" EXACT [UniProtKB:Q00535] xref: EMBL:AAH05115.1 xref: EMBL:AAL15435.1 xref: EMBL:AAP35326.1 xref: EMBL:CAA47007.1 xref: UniProtKB:Q00535 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004302 ! CDK5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007828 ! cdk5-cdk5r1-1 direct interaction relationship: participates_in CCO:I0007829 ! cdk5-cdk5r1-2 direct interaction relationship: participates_in CCO:I0007830 ! cdk5-cdk5r1-3 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0002160 ! receptor clustering relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011113 ! CDK5_HUMAN-Phosphothreonine14 relationship: transforms_into CCO:B0011114 ! CDK5_HUMAN-Phosphotyrosine15 relationship: transforms_into CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 [Term] id: CCO:B0001712 name: MDM2_HUMAN def: "E3 ubiquitin-protein ligase Mdm2" [UniProtKB:Q00987] synonym: "Double minute 2 protein" EXACT [UniProtKB:Q00987] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q00987] synonym: "Hdm2" EXACT [UniProtKB:Q00987] synonym: "Oncoprotein Mdm2" EXACT [UniProtKB:Q00987] synonym: "p53-binding protein Mdm2" EXACT [UniProtKB:Q00987] xref: EMBL:AAA60568.1 xref: EMBL:AAA75514.1 xref: EMBL:AAA75515.1 xref: EMBL:AAA75516.1 xref: EMBL:AAA75517.1 xref: EMBL:AAA75518.1 xref: EMBL:AAA82061.1 xref: EMBL:AAA82237.1 xref: EMBL:AAF42995.1 xref: EMBL:AAL40179.1 xref: EMBL:AAL40180.1 xref: EMBL:AAM78554.1 xref: EMBL:AAP35922.1 xref: EMBL:CAA78055.1 xref: EMBL:CAB64448.1 xref: UniProtKB:Q00987 xref: UniProtKB:Q13226 xref: UniProtKB:Q13297 xref: UniProtKB:Q13298 xref: UniProtKB:Q13299 xref: UniProtKB:Q13300 xref: UniProtKB:Q13301 xref: UniProtKB:Q53XW0 xref: UniProtKB:Q71TW9 xref: UniProtKB:Q8WYJ1 xref: UniProtKB:Q8WYJ2 xref: UniProtKB:Q9UGI3 xref: UniProtKB:Q9UMT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005052 ! MDM2_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0003603 ! negative regulator of basal transcription activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006016 ! mdm2-mdm4-1 physical interaction relationship: participates_in CCO:I0006221 ! mdm2-daxx physical interaction relationship: participates_in CCO:I0006222 ! ubp7-daxx physical interaction relationship: participates_in CCO:I0006318 ! mdm2-npm1-4 physical interaction relationship: participates_in CCO:I0006349 ! mdm2-daxx-1 physical interaction relationship: participates_in CCO:I0006527 ! mdm2-npm1-2 physical interaction relationship: participates_in CCO:I0006528 ! mdm2-npm1-6 physical interaction relationship: participates_in CCO:I0006560 ! ubp7-daxx-5 physical interaction relationship: participates_in CCO:I0006805 ! esr1-mdm2 physical interaction relationship: participates_in CCO:I0006902 ! ubp7-daxx-4 physical interaction relationship: participates_in CCO:I0006903 ! daxx-mdm2-1 physical interaction relationship: participates_in CCO:I0006925 ! esr1-mdm2-1 physical interaction relationship: participates_in CCO:I0006926 ! p53-mdm2-2 physical interaction relationship: participates_in CCO:I0007070 ! mdm2-tbp-1 physical interaction relationship: participates_in CCO:I0007099 ! mdm2-p53-1 direct interaction relationship: participates_in CCO:I0007299 ! daxx-mdm2 colocalization relationship: participates_in CCO:I0007339 ! mdm2-mdm4-2 physical interaction relationship: participates_in CCO:I0007340 ! mdm2-mdm4-3 physical interaction relationship: participates_in CCO:I0007381 ! ubp7-daxx-6 physical interaction relationship: participates_in CCO:I0007387 ! usp7-mdm2 physical interaction relationship: participates_in CCO:I0007388 ! usp7-mdm2-1 physical interaction relationship: participates_in CCO:I0007389 ! usp7-mdm2-2 physical interaction relationship: participates_in CCO:I0007407 ! mdm2-mdm4-4 physical interaction relationship: participates_in CCO:I0007462 ! usp7-mdm2-5 direct interaction relationship: participates_in CCO:I0007753 ! mdm2-npm1-1 physical interaction relationship: participates_in CCO:I0007808 ! ubp7-daxx-7 physical interaction relationship: participates_in CCO:I0007809 ! ubp7-daxx-8 physical interaction relationship: participates_in CCO:I0007810 ! ubp7-daxx-9 physical interaction relationship: participates_in CCO:I0007811 ! mdm2-daxx-2 physical interaction relationship: participates_in CCO:I0007812 ! usp7-hausp physical interaction relationship: participates_in CCO:I0007815 ! usp7-mdm2-4 direct interaction relationship: participates_in CCO:I0007930 ! usp7-mdm2-3 direct interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001713 name: E2F1_HUMAN def: "Transcription factor E2F1" [UniProtKB:Q01094] synonym: "E2F-1" EXACT [UniProtKB:Q01094] synonym: "PBR3" EXACT [UniProtKB:Q01094] synonym: "PRB-binding protein E2F-1" EXACT [UniProtKB:Q01094] synonym: "RBAP-1" EXACT [UniProtKB:Q01094] synonym: "RBBP-3" EXACT [UniProtKB:Q01094] synonym: "Retinoblastoma-associated protein 1" EXACT [UniProtKB:Q01094] synonym: "Retinoblastoma-binding protein 3" EXACT [UniProtKB:Q01094] xref: EMBL:AAA35782.1 xref: EMBL:AAB24289.1 xref: EMBL:AAC50719.1 xref: EMBL:AAD14150.1 xref: EMBL:AAH50369.1 xref: EMBL:AAH58902.1 xref: EMBL:AAM47604.1 xref: EMBL:CAC08486.1 xref: UniProtKB:Q01094 xref: UniProtKB:Q13143 xref: UniProtKB:Q92768 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004533 ! E2F1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006017 ! e2f1-trrap-1 physical interaction relationship: participates_in CCO:I0006055 ! pa2g4-e2f1-1 physical interaction relationship: participates_in CCO:I0007003 ! e2f3-rb physical interaction relationship: participates_in CCO:I0007008 ! e2f3-rb-1 physical interaction relationship: participates_in CCO:I0007009 ! e2f3-rb-2 physical interaction relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0011620 ! E2F1_HUMAN-Phosphoserine375 [Term] id: CCO:B0001714 name: XPC_HUMAN def: "DNA repair protein complementing XP-C cells" [UniProtKB:Q01831] synonym: "p125" EXACT [UniProtKB:Q01831] synonym: "Xeroderma pigmentosum group C-complementing protein" EXACT [UniProtKB:Q01831] xref: EMBL:AAF87574.1 xref: EMBL:AAH16620.1 xref: EMBL:AAM77801.1 xref: EMBL:BAA04651.1 xref: EMBL:BAD96564.1 xref: EMBL:CAA46158.1 xref: UniProtKB:Q01831 xref: UniProtKB:Q53GT7 xref: UniProtKB:Q96AX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005939 ! XPC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006495 ! lsm3-xpc physical interaction relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000186 ! intra-S DNA damage checkpoint relationship: transforms_into CCO:B0014708 ! XPC_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0014709 ! XPC_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0014710 ! XPC_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0014711 ! XPC_HUMAN-Phosphoserine883 relationship: transforms_into CCO:B0014712 ! XPC_HUMAN-Phosphoserine884 relationship: transforms_into CCO:B0014713 ! XPC_HUMAN-Phosphoserine892 relationship: transforms_into CCO:B0071889 ! XPC_HUMAN-Phosphothreonine169 relationship: transforms_into CCO:B0071890 ! XPC_HUMAN-Phosphoserine891 [Term] id: CCO:B0001715 name: CENPE_HUMAN def: "Centromeric protein E" [UniProtKB:Q02224] synonym: "CENP-E" EXACT [UniProtKB:Q02224] xref: EMBL:BAE06078.1 xref: EMBL:CAA78727.1 xref: EMBL:EAX06171.1 xref: UniProtKB:A6NKY9 xref: UniProtKB:Q02224 xref: UniProtKB:Q4LE75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004324 ! CENPE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000019 ! mitotic metaphase relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000093 ! mitotic chromosome movement towards spindle pole relationship: participates_in CCO:P0000094 ! mitotic metaphase plate congression relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011146 ! CENPE_HUMAN-Phosphothreonine422 relationship: transforms_into CCO:B0011147 ! CENPE_HUMAN-Phosphoserine454 relationship: transforms_into CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: transforms_into CCO:B0011149 ! CENPE_HUMAN-Phosphoserine611 relationship: transforms_into CCO:B0011150 ! CENPE_HUMAN-Phosphoserine1211 relationship: transforms_into CCO:B0011151 ! CENPE_HUMAN-Phosphothreonine1268 relationship: transforms_into CCO:B0011152 ! CENPE_HUMAN-Phosphoserine2639 relationship: transforms_into CCO:B0011153 ! CENPE_HUMAN-Phosphoserine2651 relationship: transforms_into CCO:B0011154 ! CENPE_HUMAN-Phosphoserine2654 relationship: transforms_into CCO:B0064279 ! CENPE_HUMAN-Phosphoserine2647 [Term] id: CCO:B0001716 name: KIF23_HUMAN def: "Kinesin-like protein KIF23" [UniProtKB:Q02241] synonym: "Kinesin-like protein 5" EXACT [UniProtKB:Q02241] synonym: "Mitotic kinesin-like protein 1" EXACT [UniProtKB:Q02241] xref: EMBL:AAH17705.2 xref: EMBL:AAH51826.1 xref: EMBL:CAA47628.2 xref: UniProtKB:Q02241 xref: UniProtKB:Q8WVP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004944 ! KIF23_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000001 ! mitotic spindle elongation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012590 ! KIF23_HUMAN-Phosphotyrosine29 relationship: transforms_into CCO:B0012591 ! KIF23_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0012592 ! KIF23_HUMAN-Phosphoserine160 relationship: transforms_into CCO:B0012593 ! KIF23_HUMAN-Phosphothreonine450 relationship: transforms_into CCO:B0012594 ! KIF23_HUMAN-Phosphoserine682 relationship: transforms_into CCO:B0012595 ! KIF23_HUMAN-Phosphoserine684 relationship: transforms_into CCO:B0012596 ! KIF23_HUMAN-Phosphoserine686 relationship: transforms_into CCO:B0012597 ! KIF23_HUMAN-Phosphothreonine738 relationship: transforms_into CCO:B0012598 ! KIF23_HUMAN-Phosphoserine814 relationship: transforms_into CCO:B0012599 ! KIF23_HUMAN-Phosphoserine867 relationship: transforms_into CCO:B0012600 ! KIF23_HUMAN-Phosphoserine902 relationship: transforms_into CCO:B0012601 ! KIF23_HUMAN-Phosphoserine911 relationship: transforms_into CCO:B0012602 ! KIF23_HUMAN-Phosphoserine912 relationship: transforms_into CCO:B0048308 ! KIF23_HUMAN-Phosphothreonine913 relationship: transforms_into CCO:B0067361 ! KIF23_HUMAN-Phosphothreonine861 [Term] id: CCO:B0001717 name: ID3_HUMAN def: "DNA-binding protein inhibitor ID-3" [UniProtKB:Q02535] synonym: "Helix-loop-helix protein HEIR-1" EXACT [UniProtKB:Q02535] synonym: "ID-like protein inhibitor HLH 1R21" EXACT [UniProtKB:Q02535] synonym: "Inhibitor of DNA binding 3" EXACT [UniProtKB:Q02535] xref: EMBL:AAH03107.1 xref: EMBL:AAP35437.1 xref: EMBL:CAA15950.1 xref: EMBL:CAA47360.1 xref: EMBL:CAA48862.1 xref: EMBL:CAA51827.1 xref: UniProtKB:O75641 xref: UniProtKB:Q02535 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004849 ! ID3_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000639 ! regulation of DNA replication relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0001718 name: MP2K1_HUMAN def: "Dual specificity mitogen-activated protein kinase kinase 1" [UniProtKB:Q02750] synonym: "EC 2.7.12.2" EXACT [UniProtKB:Q02750] synonym: "ERK activator kinase 1" EXACT [UniProtKB:Q02750] synonym: "MAP kinase kinase 1" EXACT [UniProtKB:Q02750] synonym: "MAPK/ERK kinase 1" EXACT [UniProtKB:Q02750] synonym: "MAPKK 1" EXACT [UniProtKB:Q02750] synonym: "MEK1" EXACT [UniProtKB:Q02750] xref: EMBL:AAA36318.1 xref: UniProtKB:Q02750 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005113 ! MAP2K1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007735 ! trib1-map2k1-1 physical interaction relationship: participates_in CCO:I0007736 ! trib3-map2k1-2 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0012974 ! MP2K1_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0012975 ! MP2K1_HUMAN-Phosphoserine222 [Term] id: CCO:B0001719 name: NOTC2_HUMAN def: "Neurogenic locus notch homolog protein 2 precursor" [UniProtKB:Q04721] synonym: "hN2" EXACT [UniProtKB:Q04721] synonym: "Notch 2" EXACT [UniProtKB:Q04721] xref: EMBL:AAA36377.2 xref: EMBL:AAB19224.1 xref: EMBL:AAG37073.1 xref: EMBL:CAH70182.1 xref: EMBL:CAH72483.1 xref: EMBL:CAI18974.1 xref: UniProtKB:Q04721 xref: UniProtKB:Q5T3X7 xref: UniProtKB:Q99734 xref: UniProtKB:Q9H240 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005209 ! NOTCH2_human relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001147 ! stem cell maintenance relationship: participates_in CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: transforms_into CCO:B0013238 ! NOTC2_HUMAN-Phosphothreonine1808 relationship: transforms_into CCO:B0013239 ! NOTC2_HUMAN-Phosphoserine1841 relationship: transforms_into CCO:B0013240 ! NOTC2_HUMAN-Phosphoserine1842 relationship: transforms_into CCO:B0013241 ! NOTC2_HUMAN-Phosphoserine1845 relationship: transforms_into CCO:B0013242 ! NOTC2_HUMAN-Phosphoserine2070 relationship: transforms_into CCO:B0013243 ! NOTC2_HUMAN-Phosphoserine2078 relationship: transforms_into CCO:B0068799 ! NOTC2_HUMAN-Phosphothreonine1716 relationship: transforms_into CCO:B0068800 ! NOTC2_HUMAN-Phosphoserine1778 relationship: transforms_into CCO:B0068801 ! NOTC2_HUMAN-Phosphothreonine1802 relationship: transforms_into CCO:B0068802 ! NOTC2_HUMAN-Phosphoserine1804 relationship: transforms_into CCO:B0068803 ! NOTC2_HUMAN-Phosphothreonine2074 relationship: transforms_into CCO:B0068804 ! NOTC2_HUMAN-Phosphoserine2081 relationship: transforms_into CCO:B0068805 ! NOTC2_HUMAN-Phosphothreonine2097 [Term] id: CCO:B0001720 name: ACVR1_HUMAN def: "Activin receptor type-1 precursor" [UniProtKB:Q04771] synonym: "Activin receptor type I" EXACT [UniProtKB:Q04771] synonym: "Activin receptor-like kinase 2" EXACT [UniProtKB:Q04771] synonym: "ACTR-I" EXACT [UniProtKB:Q04771] synonym: "ALK-2" EXACT [UniProtKB:Q04771] synonym: "EC 2.7.11.30" EXACT [UniProtKB:Q04771] synonym: "Serine/threonine-protein kinase receptor R1" EXACT [UniProtKB:Q04771] synonym: "SKR1" EXACT [UniProtKB:Q04771] synonym: "TGF-B superfamily receptor type I" EXACT [UniProtKB:Q04771] synonym: "TSR-I" EXACT [UniProtKB:Q04771] xref: EMBL:AAA36614.1 xref: EMBL:AAH33867.1 xref: EMBL:CAA80256.1 xref: UniProtKB:Q04771 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004025 ! ACVR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001716 ! negative regulation of activin receptor signaling pathway relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0035985 ! ACVR1_HUMAN-Phosphoserine501 [Term] id: CCO:B0001721 name: RAD51_HUMAN def: "DNA repair protein RAD51 homolog 1" [UniProtKB:Q06609] synonym: "hRAD51" EXACT [UniProtKB:Q06609] synonym: "HsRAD51" EXACT [UniProtKB:Q06609] xref: EMBL:AAD49705.1 xref: EMBL:AAF69145.1 xref: EMBL:AAH01459.1 xref: EMBL:AAN87149.1 xref: EMBL:BAA02962.1 xref: EMBL:BAA03189.1 xref: EMBL:CAG38796.1 xref: UniProtKB:Q06609 xref: UniProtKB:Q6FHX9 xref: UniProtKB:Q9BV60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005416 ! RAD51_human relationship: has_function CCO:F0000028 ! recombinase activity relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005804 ! single-stranded DNA-dependent ATPase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:I0006002 ! rad51-brca2-1 physical interaction relationship: participates_in CCO:I0006676 ! rad51-rad51-2 colocalization relationship: participates_in CCO:I0006841 ! brca2-rad51-2 physical interaction relationship: participates_in CCO:I0006948 ! brca2-rad51-1 physical interaction relationship: participates_in CCO:I0007010 ! brca2-rad51-9 physical interaction relationship: participates_in CCO:I0007151 ! brca2-rad51-8 physical interaction relationship: participates_in CCO:I0007233 ! rad51-tp53-1 physical interaction relationship: participates_in CCO:I0007234 ! rad51-tp53-2 physical interaction relationship: participates_in CCO:I0007438 ! rad52-rad51-1 physical interaction relationship: participates_in CCO:I0007522 ! rad51-rad51-1 physical interaction relationship: participates_in CCO:I0007723 ! brca2-rad51-4 physical interaction relationship: participates_in CCO:I0007925 ! brca2-rad51-5 physical interaction relationship: participates_in CCO:I0007926 ! brca2-rad51-6 direct interaction relationship: participates_in CCO:I0007927 ! brca2-rad51-7 physical interaction relationship: participates_in CCO:I0007944 ! rad51-rad51-6 physical interaction relationship: participates_in CCO:I0007947 ! brca2-rad51-3 physical interaction relationship: participates_in CCO:I0008041 ! rad51-chd3 physical interaction relationship: participates_in CCO:I0008155 ! rad51-vim physical interaction relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0003026 ! positive regulation of DNA ligation relationship: transforms_into CCO:B0013669 ! RAD51_HUMAN-Phosphothreonine309 [Term] id: CCO:B0001722 name: KHDR1_HUMAN def: "KH domain-containing, RNA-binding, signal transduction-associated protein 1" [UniProtKB:Q07666] synonym: "GAP-associated tyrosine phosphoprotein p62" EXACT [UniProtKB:Q07666] synonym: "p21 Ras GTPase-activating protein-associated p62" EXACT [UniProtKB:Q07666] synonym: "p68" EXACT [UniProtKB:Q07666] synonym: "Sam68" EXACT [UniProtKB:Q07666] synonym: "Src-associated in mitosis 68 kDa protein" EXACT [UniProtKB:Q07666] xref: EMBL:AAA59990.1 xref: EMBL:AAB47504.1 xref: EMBL:AAH00717.1 xref: EMBL:AAH10132.1 xref: EMBL:AAH19109.1 xref: EMBL:BAC03643.1 xref: EMBL:CAH71944.1 xref: EMBL:CAH71945.1 xref: EMBL:CAI21971.1 xref: EMBL:CAI21972.1 xref: UniProtKB:Q07666 xref: UniProtKB:Q6PJX7 xref: UniProtKB:Q8NB97 xref: UniProtKB:Q99760 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004937 ! KHDRBS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006615 ! khdrbs1-ptpn6-1 physical interaction relationship: participates_in CCO:I0006616 ! khdrbs1-fyn-1 physical interaction relationship: participates_in CCO:I0006617 ! khdrbs1-plcg1-1 physical interaction relationship: participates_in CCO:I0006618 ! khdrbs1-grb2-1 physical interaction relationship: participates_in CCO:I0006619 ! khdrbs1-cbl-1 physical interaction relationship: participates_in CCO:I0006620 ! khdrbs1-jak3-1 physical interaction relationship: participates_in CCO:I0006621 ! khdrbs1-grb2-2 physical interaction relationship: participates_in CCO:I0006622 ! khdrbs1-jak3-2 physical interaction relationship: participates_in CCO:I0006623 ! khdrbs1-lck-1 physical interaction relationship: participates_in CCO:I0006712 ! khdrbs1-lyn-1 physical interaction relationship: participates_in CCO:I0006713 ! crebbp-khdrbs1-9 colocalization relationship: participates_in CCO:I0007088 ! khdrbs1-fyn-2 physical interaction relationship: participates_in CCO:I0007089 ! khdrbs1-fyn-3 physical interaction relationship: participates_in CCO:I0007330 ! hck-p62-1 physical interaction relationship: participates_in CCO:I0007346 ! khdrbs1-stat3-1 physical interaction relationship: participates_in CCO:I0007347 ! khdrbs1-stat3-2 physical interaction relationship: participates_in CCO:I0007477 ! smarca2-sam68 physical interaction relationship: participates_in CCO:I0007512 ! smarca2-sam68-1 physical interaction relationship: participates_in CCO:I0007519 ! lck-khdrbs1 physical interaction relationship: participates_in CCO:I0007964 ! hck-sam68-1 physical interaction relationship: participates_in CCO:I0007965 ! lck-sam68-1 physical interaction relationship: participates_in CCO:I0007966 ! grb2-sam68-1 physical interaction relationship: participates_in CCO:I0007967 ! grb2-sam68-2 physical interaction relationship: participates_in CCO:I0008166 ! src-khdrbs1 physical interaction relationship: participates_in CCO:I0008183 ! tubb4-khdrbs1 physical interaction relationship: participates_in CCO:I0008364 ! c2f-khdrbs1 physical interaction relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0012514 ! KHDR1_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0012515 ! KHDR1_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0012516 ! KHDR1_HUMAN-Phosphothreonine33 relationship: transforms_into CCO:B0012517 ! KHDR1_HUMAN-dimethylarginine45 relationship: transforms_into CCO:B0012518 ! KHDR1_HUMAN-dimethylarginine52 relationship: transforms_into CCO:B0012519 ! KHDR1_HUMAN-arginine291 relationship: transforms_into CCO:B0012520 ! KHDR1_HUMAN-dimethylarginine304 relationship: transforms_into CCO:B0012521 ! KHDR1_HUMAN-Omega-N-methylarginine310 relationship: transforms_into CCO:B0012522 ! KHDR1_HUMAN-Omega-N-methylarginine315 relationship: transforms_into CCO:B0012523 ! KHDR1_HUMAN-Omega-N-methylarginine320 relationship: transforms_into CCO:B0012524 ! KHDR1_HUMAN-Omega-N-methylarginine325 relationship: transforms_into CCO:B0012525 ! KHDR1_HUMAN-arginine331 relationship: transforms_into CCO:B0012526 ! KHDR1_HUMAN-Omega-N-methylarginine340 relationship: transforms_into CCO:B0012527 ! KHDR1_HUMAN-arginine346 relationship: transforms_into CCO:B0041154 ! KHDR1_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0067298 ! KHDR1_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0067299 ! KHDR1_HUMAN-Phosphoserine29 [Term] id: CCO:B0001723 name: BAX_HUMAN def: "Apoptosis regulator BAX" [UniProtKB:Q07812] xref: EMBL:AAA03619.1 xref: EMBL:AAA03620.1 xref: EMBL:AAA03621.1 xref: EMBL:AAC50142.1 xref: EMBL:AAD22706.1 xref: EMBL:AAF82094.1 xref: EMBL:AAH14175.1 xref: EMBL:AAO22992.1 xref: EMBL:CAD10744.1 xref: EMBL:EAW52418.1 xref: UniProtKB:P55269 xref: UniProtKB:Q07812 xref: UniProtKB:Q07814 xref: UniProtKB:Q07815 xref: UniProtKB:Q8WZ49 xref: UniProtKB:Q9NR76 xref: UniProtKB:Q9UQD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004143 ! BAX_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006207 ! bcl2-bax-2 physical interaction relationship: participates_in CCO:I0007343 ! bcl_xl-bax physical interaction relationship: participates_in CCO:I0007445 ! bax-bcl2-1 physical interaction relationship: participates_in CCO:I0007764 ! bak-bax-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis [Term] id: CCO:B0001724 name: DPOE1_HUMAN def: "DNA polymerase epsilon catalytic subunit A" [UniProtKB:Q07864] synonym: "DNA polymerase II subunit A" EXACT [UniProtKB:Q07864] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q07864] xref: EMBL:AAA15448.1 xref: EMBL:AAA90924.1 xref: EMBL:AAC19148.1 xref: EMBL:AAP12650.1 xref: UniProtKB:Q07864 xref: UniProtKB:Q13533 xref: UniProtKB:Q86VH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004505 ! POLE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007291 ! pole3-pole4-6 physical interaction relationship: participates_in CCO:I0007334 ! stk19-pole physical interaction relationship: participates_in CCO:I0007363 ! pole3-pole4-3 physical interaction relationship: participates_in CCO:I0007364 ! pole3-pole4-4 physical interaction relationship: participates_in CCO:I0007913 ! dpol-epsilon_human physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0011577 ! DPOE1_HUMAN-Phosphoserine1940 [Term] id: CCO:B0001725 name: RBL2_HUMAN def: "Retinoblastoma-like protein 2" [UniProtKB:Q08999] synonym: "130 kDa retinoblastoma-associated protein" EXACT [UniProtKB:Q08999] synonym: "p130" EXACT [UniProtKB:Q08999] synonym: "PRB2" EXACT [UniProtKB:Q08999] synonym: "RBR-2" EXACT [UniProtKB:Q08999] xref: EMBL:AAB29227.1 xref: EMBL:AAC50479.1 xref: EMBL:CAA52671.1 xref: EMBL:CAA53661.1 xref: UniProtKB:Q08999 xref: UniProtKB:Q15073 xref: UniProtKB:Q16084 xref: UniProtKB:Q92812 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005446 ! RBL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013765 ! RBL2_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0013766 ! RBL2_HUMAN-Phosphothreonine417 relationship: transforms_into CCO:B0013767 ! RBL2_HUMAN-Phosphoserine639 relationship: transforms_into CCO:B0013768 ! RBL2_HUMAN-Phosphothreonine642 relationship: transforms_into CCO:B0013769 ! RBL2_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0013770 ! RBL2_HUMAN-Phosphoserine948 relationship: transforms_into CCO:B0013771 ! RBL2_HUMAN-Phosphoserine952 relationship: transforms_into CCO:B0013772 ! RBL2_HUMAN-Phosphoserine966 relationship: transforms_into CCO:B0013773 ! RBL2_HUMAN-Phosphoserine971 relationship: transforms_into CCO:B0013774 ! RBL2_HUMAN-Phosphoserine972 relationship: transforms_into CCO:B0013775 ! RBL2_HUMAN-Phosphoserine973 relationship: transforms_into CCO:B0013776 ! RBL2_HUMAN-Phosphothreonine974 relationship: transforms_into CCO:B0013777 ! RBL2_HUMAN-Phosphoserine981 relationship: transforms_into CCO:B0013778 ! RBL2_HUMAN-Phosphoserine982 relationship: transforms_into CCO:B0013779 ! RBL2_HUMAN-Phosphothreonine986 relationship: transforms_into CCO:B0036026 ! RBL2_HUMAN-Phosphothreonine1019 [Term] id: CCO:B0001726 name: DMWD_HUMAN def: "Dystrophia myotonica WD repeat-containing protein" [UniProtKB:Q09019] synonym: "DMR-N9 protein" EXACT [UniProtKB:Q09019] synonym: "Dystrophia myotonica-containing WD repeat motif protein" EXACT [UniProtKB:Q09019] synonym: "Protein 59" EXACT [UniProtKB:Q09019] xref: EMBL:AAA35767.1 xref: EMBL:AAC14447.1 xref: UniProtKB:Q09019 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004486 ! DMWD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008469 ! dmwd-ppbp physical interaction relationship: participates_in CCO:P0000117 ! meiosis relationship: transforms_into CCO:B0064790 ! DMWD_HUMAN-Phosphoserine545 [Term] id: CCO:B0001727 name: RBBP4_HUMAN def: "Histone-binding protein RBBP4" [UniProtKB:Q09028] synonym: "CAF-1 subunit C" EXACT [UniProtKB:Q09028] synonym: "CAF-I 48 kDa subunit" EXACT [UniProtKB:Q09028] synonym: "CAF-I p48" EXACT [UniProtKB:Q09028] synonym: "Chromatin assembly factor 1 subunit C" EXACT [UniProtKB:Q09028] synonym: "Chromatin assembly factor I p48 subunit" EXACT [UniProtKB:Q09028] synonym: "Nucleosome-remodeling factor subunit RBAP48" EXACT [UniProtKB:Q09028] synonym: "RBBP-4" EXACT [UniProtKB:Q09028] synonym: "Retinoblastoma-binding protein 4" EXACT [UniProtKB:Q09028] synonym: "Retinoblastoma-binding protein p48" EXACT [UniProtKB:Q09028] xref: EMBL:AAH03092.1 xref: EMBL:AAH15123.1 xref: EMBL:AAH53904.1 xref: EMBL:AAH75836.1 xref: EMBL:AAP35973.1 xref: EMBL:BAD96499.1 xref: EMBL:CAA50685.1 xref: EMBL:CAA52321.1 xref: UniProtKB:P31149 xref: UniProtKB:Q09028 xref: UniProtKB:Q53H02 xref: UniProtKB:Q96BV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005438 ! RBBP4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000805 ! NuRD complex relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007869 ! hdac1-rbbp4-1 physical interaction relationship: participates_in CCO:I0008425 ! rbbp4-g22p1 physical interaction relationship: participates_in CCO:I0008502 ! rpn1-rbbp4 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0013719 ! RBBP4_HUMAN-N-acetylalanine2 [Term] id: CCO:B0001728 name: EP300_HUMAN def: "Histone acetyltransferase p300" [UniProtKB:Q09472] synonym: "E1A-associated protein p300" EXACT [UniProtKB:Q09472] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q09472] xref: EMBL:AAA18639.1 xref: UniProtKB:Q09472 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004568 ! EP300_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005775 ! peroxisome proliferator activated receptor binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000011 ! histone acetyltransferase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006050 ! ep300-nap1l1-3 direct interaction relationship: participates_in CCO:I0006524 ! zbtb17-ep300 physical interaction relationship: participates_in CCO:I0006627 ! pparg-ep300 physical interaction relationship: participates_in CCO:I0006702 ! hif1a-ep300-3 physical interaction relationship: participates_in CCO:I0006721 ! p300-tfap2a-7 physical interaction relationship: participates_in CCO:I0006724 ! p300-tfap2a-2 physical interaction relationship: participates_in CCO:I0006725 ! p300-tfap2a-3 physical interaction relationship: participates_in CCO:I0006726 ! p300-tfap2a-4 physical interaction relationship: participates_in CCO:I0006727 ! p300-tfap2a-5 physical interaction relationship: participates_in CCO:I0006787 ! myc-ep300 physical interaction relationship: participates_in CCO:I0007084 ! p53-crebbp-3 physical interaction relationship: participates_in CCO:I0007146 ! p300-tfap2a-1 physical interaction relationship: participates_in CCO:I0007147 ! p300-cited2-1 physical interaction relationship: participates_in CCO:I0007150 ! cbp-atf3 physical interaction relationship: participates_in CCO:I0007361 ! p53-p300-1 physical interaction relationship: participates_in CCO:I0007417 ! p300-tfap2a-6 physical interaction relationship: participates_in CCO:I0007529 ! hif1a-ep300-2 physical interaction relationship: participates_in CCO:I0007787 ! ep300-nap1l1-4 physical interaction relationship: participates_in CCO:I0007788 ! ep300-nap1l1-5 physical interaction relationship: participates_in CCO:I0007954 ! hif1a-ep300-1 physical interaction relationship: participates_in CCO:I0007956 ! epas1-ep300-1 physical interaction relationship: participates_in CCO:I0008227 ! ep300-cops6 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003022 ! positive regulation of transcription factor activity relationship: transforms_into CCO:B0011704 ! EP300_HUMAN-Omega-N-methylated arginine580 relationship: transforms_into CCO:B0011705 ! EP300_HUMAN-Omega-N-methylated arginine604 relationship: transforms_into CCO:B0011706 ! EP300_HUMAN-N6-acetyllysine1554 relationship: transforms_into CCO:B0011707 ! EP300_HUMAN-N6-acetyllysine1555 relationship: transforms_into CCO:B0011708 ! EP300_HUMAN-N6-acetyllysine1558 relationship: transforms_into CCO:B0011709 ! EP300_HUMAN-N6-acetyllysine1560 relationship: transforms_into CCO:B0011710 ! EP300_HUMAN-dimethylarginine2142 relationship: transforms_into CCO:B0011711 ! EP300_HUMAN-Citrulline2142 [Term] id: CCO:B0001729 name: CT069_HUMAN def: "Putative uncharacterized protein C20orf69" [UniProtKB:Q0VF47] xref: EMBL:AAI18989.1 xref: EMBL:AAI22538.1 xref: EMBL:CAC28313.1 xref: UniProtKB:Q0VF47 xref: UniProtKB:Q9BZ41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005986 ! C20orf69_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001731 name: CETN1_HUMAN def: "Centrin-1" [UniProtKB:Q12798] synonym: "Caltractin isoform 2" EXACT [UniProtKB:Q12798] xref: EMBL:AAC27343.1 xref: EMBL:AAH29515.1 xref: UniProtKB:Q12798 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004332 ! CETN1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000386 ! spindle pole body relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000110 ! mitotic centrosome separation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001732 name: SNF5_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1" [UniProtKB:Q12824] synonym: "BAF47" EXACT [UniProtKB:Q12824] synonym: "hSNF5" EXACT [UniProtKB:Q12824] synonym: "Integrase interactor 1 protein" EXACT [UniProtKB:Q12824] xref: EMBL:AAA81905.1 xref: EMBL:ABB02184.1 xref: EMBL:BAC77068.1 xref: EMBL:CAA09758.1 xref: EMBL:CAA09759.1 xref: EMBL:CAA76639.1 xref: EMBL:CAG30467.1 xref: UniProtKB:O75784 xref: UniProtKB:O95474 xref: UniProtKB:Q12824 xref: UniProtKB:Q38GA1 xref: UniProtKB:Q76N08 xref: UniProtKB:Q9UBH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005644 ! SMARCB1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0007258 ! smarcb1-arid2-1 physical interaction relationship: participates_in CCO:I0007259 ! arid2-pb1-1 physical interaction relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007356 ! pb1-arid2-3 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0008206 ! ubqln4-smarcb1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0014136 ! SNF5_HUMAN-Phosphoserine129 [Term] id: CCO:B0001733 name: CDC20_HUMAN def: "Cell division cycle protein 20 homolog" [UniProtKB:Q12834] synonym: "p55CDC" EXACT [UniProtKB:Q12834] xref: EMBL:AAA19017.1 xref: EMBL:AAD16405.1 xref: EMBL:AAH00624.1 xref: EMBL:AAH01088.1 xref: EMBL:AAH06272.1 xref: EMBL:AAH09425.1 xref: EMBL:AAH09426.1 xref: EMBL:AAH10044.1 xref: EMBL:AAH12803.1 xref: EMBL:AAH12827.1 xref: EMBL:AAH13303.1 xref: EMBL:AAH15998.1 xref: EMBL:AAH24257.1 xref: EMBL:AAH31294.1 xref: EMBL:AAI10322.1 xref: EMBL:AAP36052.1 xref: EMBL:ABE96834.1 xref: EMBL:CAB92757.1 xref: UniProtKB:Q12834 xref: UniProtKB:Q5JUY4 xref: UniProtKB:Q9BW56 xref: UniProtKB:Q9UQI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004284 ! CDC20_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011058 ! CDC20_HUMAN-Phosphothreonine70 relationship: transforms_into CCO:B0011059 ! CDC20_HUMAN-Phosphothreonine106 relationship: transforms_into CCO:B0064186 ! CDC20_HUMAN-Phosphoserine41 [Term] id: CCO:B0001734 name: ILF3_HUMAN def: "Interleukin enhancer-binding factor 3" [UniProtKB:Q12906] synonym: "Double-stranded RNA-binding protein 76" EXACT [UniProtKB:Q12906] synonym: "DRBP76" EXACT [UniProtKB:Q12906] synonym: "M-phase phosphoprotein 4" EXACT [UniProtKB:Q12906] synonym: "MPP4" EXACT [UniProtKB:Q12906] synonym: "NF-AT-90" EXACT [UniProtKB:Q12906] synonym: "NFAR" EXACT [UniProtKB:Q12906] synonym: "Nuclear factor associated with dsRNA" EXACT [UniProtKB:Q12906] synonym: "Nuclear factor of activated T-cells 90 kDa" EXACT [UniProtKB:Q12906] synonym: "TCP80" EXACT [UniProtKB:Q12906] synonym: "Translational control protein 80" EXACT [UniProtKB:Q12906] xref: EMBL:AAA20994.1 xref: EMBL:AAC19152.1 xref: EMBL:AAD33966.1 xref: EMBL:AAD37575.1 xref: EMBL:AAD51098.1 xref: EMBL:AAD51099.1 xref: EMBL:AAF82685.1 xref: EMBL:AAF82686.1 xref: EMBL:AAF82687.1 xref: EMBL:AAH48314.1 xref: EMBL:AAH64836.1 xref: EMBL:AAK07424.1 xref: EMBL:AAK07425.1 xref: EMBL:CAA66917.1 xref: EMBL:CAA66918.1 xref: EMBL:CAC01121.1 xref: EMBL:CAC01122.1 xref: EMBL:CAC01123.1 xref: EMBL:CAC01124.1 xref: EMBL:CAC01404.1 xref: EMBL:CAC01405.1 xref: EMBL:CAC01406.1 xref: EMBL:CAC01407.1 xref: UniProtKB:O43409 xref: UniProtKB:Q12906 xref: UniProtKB:Q6P1X1 xref: UniProtKB:Q86XY7 xref: UniProtKB:Q99544 xref: UniProtKB:Q99545 xref: UniProtKB:Q9BZH4 xref: UniProtKB:Q9BZH5 xref: UniProtKB:Q9NQ95 xref: UniProtKB:Q9NQ96 xref: UniProtKB:Q9NQ97 xref: UniProtKB:Q9NQ98 xref: UniProtKB:Q9NQ99 xref: UniProtKB:Q9NQA0 xref: UniProtKB:Q9NQA1 xref: UniProtKB:Q9NQA2 xref: UniProtKB:Q9NRN2 xref: UniProtKB:Q9NRN3 xref: UniProtKB:Q9NRN4 xref: UniProtKB:Q9UMZ9 xref: UniProtKB:Q9UN00 xref: UniProtKB:Q9UN84 xref: UniProtKB:Q9UNA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004884 ! ILF3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006991 ! hrmt1l2-ilf3-2 methylation relationship: participates_in CCO:I0007785 ! hrmt1l2-ilf3-3 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008251 ! ilf3-gdf9 physical interaction relationship: participates_in CCO:P0000039 ! M phase relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012366 ! ILF3_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0012367 ! ILF3_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0012368 ! ILF3_HUMAN-Phosphoserine382 relationship: transforms_into CCO:B0012369 ! ILF3_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0012370 ! ILF3_HUMAN-Phosphoserine482 relationship: transforms_into CCO:B0012371 ! ILF3_HUMAN-Phosphothreonine592 relationship: transforms_into CCO:B0012372 ! ILF3_HUMAN-Omega-N-methylated arginine609 relationship: transforms_into CCO:B0012373 ! ILF3_HUMAN-Phosphoserine812 relationship: transforms_into CCO:B0048284 ! ILF3_HUMAN-Phosphothreonine486 relationship: transforms_into CCO:B0067084 ! ILF3_HUMAN-Phosphotyrosine579 relationship: transforms_into CCO:B0067085 ! ILF3_HUMAN-Phosphoserine792 relationship: transforms_into CCO:B0067086 ! ILF3_HUMAN-Phosphoserine810 [Term] id: CCO:B0001735 name: FOXC1_HUMAN def: "Forkhead box protein C1" [UniProtKB:Q12948] synonym: "Forkhead-related protein FKHL7" EXACT [UniProtKB:Q12948] synonym: "Forkhead-related transcription factor 3" EXACT [UniProtKB:Q12948] synonym: "FREAC-3" EXACT [UniProtKB:Q12948] xref: EMBL:AAA92038.1 xref: EMBL:AAC18081.1 xref: EMBL:AAC72915.1 xref: EMBL:AAK13575.1 xref: EMBL:AAP15181.1 xref: EMBL:CAB81658.1 xref: UniProtKB:Q12948 xref: UniProtKB:Q86UP7 xref: UniProtKB:Q9BYM1 xref: UniProtKB:Q9NUE5 xref: UniProtKB:Q9UDD0 xref: UniProtKB:Q9UP06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004654 ! FOXC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0003231 ! cardiac muscle cell proliferation relationship: transforms_into CCO:B0066252 ! FOXC1_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0066253 ! FOXC1_HUMAN-Phosphoserine241 [Term] id: CCO:B0001736 name: DLG1_HUMAN def: "Disks large homolog 1" [UniProtKB:Q12959] synonym: "hDlg" EXACT [UniProtKB:Q12959] synonym: "SAP-97" EXACT [UniProtKB:Q12959] synonym: "Synapse-associated protein 97" EXACT [UniProtKB:Q12959] xref: EMBL:AAA50598.1 xref: EMBL:AAA50599.1 xref: UniProtKB:Q12958 xref: UniProtKB:Q12959 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004478 ! DLG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006386 ! map3k3-dlg1 physical interaction relationship: participates_in CCO:I0007135 ! dlg1-kif13b-3 physical interaction relationship: participates_in CCO:P0000188 ! G1/S transition checkpoint relationship: participates_in CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: participates_in CCO:P0000503 ! endothelial cell proliferation relationship: transforms_into CCO:B0011520 ! DLG1_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0011522 ! DLG1_HUMAN-Phosphothreonine683 relationship: transforms_into CCO:B0011523 ! DLG1_HUMAN-Phosphoserine684 relationship: transforms_into CCO:B0011524 ! DLG1_HUMAN-Phosphoserine687 relationship: transforms_into CCO:B0031311 ! DLG1_HUMAN-Phosphotyrosine399 relationship: transforms_into CCO:B0048225 ! DLG1_HUMAN-Phosphoserine619 relationship: transforms_into CCO:B0048226 ! DLG1_HUMAN-Phosphotyrosine760 relationship: transforms_into CCO:B0064766 ! DLG1_HUMAN-Phosphothreonine115 relationship: transforms_into CCO:B0064767 ! DLG1_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0064768 ! DLG1_HUMAN-Phosphoserine575 [Term] id: CCO:B0001737 name: STRN3_HUMAN def: "Striatin-3" [UniProtKB:Q13033] synonym: "Cell-cycle autoantigen SG2NA" EXACT [UniProtKB:Q13033] synonym: "S/G2 antigen" EXACT [UniProtKB:Q13033] xref: EMBL:AAB81551.1 xref: EMBL:AAF81201.1 xref: UniProtKB:Q13033 xref: UniProtKB:Q9NRA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005698 ! STRN3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0014268 ! STRN3_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0070978 ! STRN3_HUMAN-Phosphoserine257 [Term] id: CCO:B0001739 name: CDC16_HUMAN def: "Cell division cycle protein 16 homolog" [UniProtKB:Q13042] synonym: "Anaphase-promoting complex subunit 6" EXACT [UniProtKB:Q13042] synonym: "APC6" EXACT [UniProtKB:Q13042] synonym: "CDC16Hs" EXACT [UniProtKB:Q13042] synonym: "Cyclosome subunit 6" EXACT [UniProtKB:Q13042] xref: EMBL:AAC50200.1 xref: EMBL:AAD45156.1 xref: EMBL:AAH17244.1 xref: EMBL:AAS94323.1 xref: UniProtKB:Q13042 xref: UniProtKB:Q96AE6 xref: UniProtKB:Q9Y564 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004283 ! CDC16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007929 ! cdc27-nek2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011052 ! CDC16_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0011053 ! CDC16_HUMAN-Phosphoserine490 relationship: transforms_into CCO:B0011054 ! CDC16_HUMAN-Phosphoserine560 relationship: transforms_into CCO:B0011055 ! CDC16_HUMAN-Phosphothreonine581 relationship: transforms_into CCO:B0011056 ! CDC16_HUMAN-Phosphoserine595 relationship: transforms_into CCO:B0011057 ! CDC16_HUMAN-Phosphothreonine599 [Term] id: CCO:B0001740 name: CSN1_HUMAN def: "COP9 signalosome complex subunit 1" [UniProtKB:Q13098] synonym: "G protein pathway suppressor 1" EXACT [UniProtKB:Q13098] synonym: "JAB1-containing signalosome subunit 1" EXACT [UniProtKB:Q13098] synonym: "Protein GPS1" EXACT [UniProtKB:Q13098] synonym: "Protein MFH" EXACT [UniProtKB:Q13098] synonym: "SGN1" EXACT [UniProtKB:Q13098] synonym: "Signalosome subunit 1" EXACT [UniProtKB:Q13098] xref: EMBL:AAC50906.2 xref: EMBL:AAH00155.3 xref: EMBL:AAH64503.1 xref: EMBL:AAP88836.1 xref: EMBL:BAC04120.1 xref: UniProtKB:Q13098 xref: UniProtKB:Q8NA10 xref: UniProtKB:Q9BWL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004407 ! GPS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008479 ! gps1-tbc1d17 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0011357 ! CSN1_HUMAN-Phosphoserine448 relationship: transforms_into CCO:B0011358 ! CSN1_HUMAN-Phosphoserine454 relationship: transforms_into CCO:B0011359 ! CSN1_HUMAN-Phosphothreonine459 relationship: transforms_into CCO:B0011360 ! CSN1_HUMAN-Phosphoserine463 relationship: transforms_into CCO:B0011361 ! CSN1_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0048207 ! CSN1_HUMAN-Phosphotyrosine357 [Term] id: CCO:B0001741 name: ZBT17_HUMAN def: "Zinc finger and BTB domain-containing protein 17" [UniProtKB:Q13105] synonym: "Miz-1" EXACT [UniProtKB:Q13105] synonym: "Myc-interacting zinc finger protein" EXACT [UniProtKB:Q13105] synonym: "Zinc finger protein 151" EXACT [UniProtKB:Q13105] synonym: "Zinc finger protein 60" EXACT [UniProtKB:Q13105] xref: EMBL:AAA61327.1 xref: EMBL:AAC50256.1 xref: EMBL:AAI26164.1 xref: EMBL:CAA70889.1 xref: EMBL:CAB85445.1 xref: EMBL:CAI19524.1 xref: UniProtKB:A0AV07 xref: UniProtKB:Q13105 xref: UniProtKB:Q15932 xref: UniProtKB:Q5JYB2 xref: UniProtKB:Q9NUC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005952 ! ZBTB17_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006313 ! hcfc1-zbtb17-9 physical interaction relationship: participates_in CCO:I0006523 ! hcfc1-zbtb17-3 physical interaction relationship: participates_in CCO:I0006524 ! zbtb17-ep300 physical interaction relationship: participates_in CCO:I0006869 ! hcfc1-zbtb17-2 physical interaction relationship: participates_in CCO:I0007005 ! myc-zbtb17-1 physical interaction relationship: participates_in CCO:I0007006 ! myc-zbtb17-2 physical interaction relationship: participates_in CCO:I0007115 ! hcfc1-zbtb17-4 physical interaction relationship: participates_in CCO:I0007116 ! hcfc1-zbtb17-5 physical interaction relationship: participates_in CCO:I0007117 ! hcfc1-zbtb17-6 physical interaction relationship: participates_in CCO:I0007118 ! hcfc1-zbtb17-7 physical interaction relationship: participates_in CCO:I0007119 ! hcfc1-zbtb17-8 physical interaction relationship: participates_in CCO:I0007565 ! hcfc1-zbtb17-1 physical interaction relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001742 name: CAF1A_HUMAN def: "Chromatin assembly factor 1 subunit A" [UniProtKB:Q13111] synonym: "CAF-1 subunit A" EXACT [UniProtKB:Q13111] synonym: "CAF-I 150 kDa subunit" EXACT [UniProtKB:Q13111] synonym: "CAF-Ip150" EXACT [UniProtKB:Q13111] synonym: "Chromatin assembly factor I p150 subunit" EXACT [UniProtKB:Q13111] xref: EMBL:AAA76736.1 xref: EMBL:AAF04291.1 xref: EMBL:AAH52620.1 xref: UniProtKB:Q13111 xref: UniProtKB:Q7Z7K3 xref: UniProtKB:Q9UJY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004212 ! CHAF1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005986 ! pcna-pold1-1 physical interaction relationship: participates_in CCO:I0005987 ! pcna-pold1-2 physical interaction relationship: participates_in CCO:I0006807 ! h3-caf1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010891 ! CAF1A_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0010892 ! CAF1A_HUMAN-Phosphoserine123 relationship: transforms_into CCO:B0010893 ! CAF1A_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0010894 ! CAF1A_HUMAN-Phosphoserine185 relationship: transforms_into CCO:B0010895 ! CAF1A_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0010896 ! CAF1A_HUMAN-Phosphoserine237 relationship: transforms_into CCO:B0010897 ! CAF1A_HUMAN-Phosphothreonine241 relationship: transforms_into CCO:B0010898 ! CAF1A_HUMAN-Phosphoserine754 relationship: transforms_into CCO:B0010899 ! CAF1A_HUMAN-Phosphoserine933 relationship: transforms_into CCO:B0064047 ! CAF1A_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0064048 ! CAF1A_HUMAN-Phosphothreonine704 relationship: transforms_into CCO:B0064049 ! CAF1A_HUMAN-Phosphoserine855 [Term] id: CCO:B0001743 name: CAF1B_HUMAN def: "Chromatin assembly factor 1 subunit B" [UniProtKB:Q13112] synonym: "CAF-1 subunit B" EXACT [UniProtKB:Q13112] synonym: "CAF-I 60 kDa subunit" EXACT [UniProtKB:Q13112] synonym: "CAF-Ip60" EXACT [UniProtKB:Q13112] synonym: "Chromatin assembly factor I p60 subunit" EXACT [UniProtKB:Q13112] synonym: "M-phase phosphoprotein 7" EXACT [UniProtKB:Q13112] xref: EMBL:AAA76737.1 xref: EMBL:AAH21218.1 xref: EMBL:BAA89426.1 xref: EMBL:BAA95549.1 xref: EMBL:CAA66915.1 xref: UniProtKB:Q13112 xref: UniProtKB:Q99548 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004213 ! CHAF1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006807 ! h3-caf1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010900 ! CAF1B_HUMAN-Phosphoserine429 relationship: transforms_into CCO:B0010901 ! CAF1B_HUMAN-Phosphoserine458 relationship: transforms_into CCO:B0010902 ! CAF1B_HUMAN-Phosphothreonine485 relationship: transforms_into CCO:B0010903 ! CAF1B_HUMAN-Phosphothreonine495 relationship: transforms_into CCO:B0010904 ! CAF1B_HUMAN-Phosphothreonine503 relationship: transforms_into CCO:B0010905 ! CAF1B_HUMAN-Phosphothreonine509 relationship: transforms_into CCO:B0010906 ! CAF1B_HUMAN-Phosphothreonine521 relationship: transforms_into CCO:B0010907 ! CAF1B_HUMAN-Phosphothreonine531 relationship: transforms_into CCO:B0010908 ! CAF1B_HUMAN-Phosphoserine538 relationship: transforms_into CCO:B0064050 ! CAF1B_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0064051 ! CAF1B_HUMAN-Phosphothreonine419 relationship: transforms_into CCO:B0064052 ! CAF1B_HUMAN-Phosphothreonine433 relationship: transforms_into CCO:B0064053 ! CAF1B_HUMAN-Phosphothreonine524 [Term] id: CCO:B0001744 name: DUS4_HUMAN def: "Dual specificity protein phosphatase 4" [UniProtKB:Q13115] synonym: "Dual specificity protein phosphatase hVH2" EXACT [UniProtKB:Q13115] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q13115] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q13115] synonym: "MAP kinase phosphatase 2" EXACT [UniProtKB:Q13115] synonym: "Mitogen-activated protein kinase phosphatase 2" EXACT [UniProtKB:Q13115] synonym: "MKP-2" EXACT [UniProtKB:Q13115] xref: EMBL:AAA85119.1 xref: EMBL:AAC50452.1 xref: EMBL:AAH02671.1 xref: EMBL:AAH14565.1 xref: UniProtKB:Q13115 xref: UniProtKB:Q13524 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004522 ! DUSP4_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0001839 ! protein tyrosine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:B0001745 name: PSMD2_HUMAN def: "26S proteasome non-ATPase regulatory subunit 2" [UniProtKB:Q13200] synonym: "26S proteasome regulatory subunit RPN1" EXACT [UniProtKB:Q13200] synonym: "26S proteasome regulatory subunit S2" EXACT [UniProtKB:Q13200] synonym: "26S proteasome subunit p97" EXACT [UniProtKB:Q13200] synonym: "55.11 protein" EXACT [UniProtKB:Q13200] synonym: "Tumor necrosis factor type 1 receptor-associated protein 2" EXACT [UniProtKB:Q13200] xref: EMBL:AAA87705.1 xref: EMBL:AAH02368.1 xref: EMBL:AAH02997.1 xref: EMBL:AAH07897.1 xref: EMBL:BAA11226.1 xref: EMBL:CAA60167.1 xref: UniProtKB:Q12932 xref: UniProtKB:Q13200 xref: UniProtKB:Q15321 xref: UniProtKB:Q96I12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005391 ! PSMD2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002079 ! proteasome regulatory particle relationship: participates_in CCO:I0005870 ! psmd2-ublcp1 physical interaction relationship: participates_in CCO:I0005939 ! psmc1-psmd2 physical interaction relationship: participates_in CCO:I0006420 ! traf6-psmd2 physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007988 ! psmd2-ptn physical interaction relationship: participates_in CCO:I0008038 ! psmd2-rif1 physical interaction relationship: participates_in CCO:I0008039 ! psmd2-unc119 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0013632 ! PSMD2_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0013633 ! PSMD2_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0013634 ! PSMD2_HUMAN-Phosphothreonine90 relationship: transforms_into CCO:B0013635 ! PSMD2_HUMAN-Phosphoserine361 [Term] id: CCO:B0001746 name: GPS2_HUMAN def: "G protein pathway suppressor 2" [UniProtKB:Q13227] synonym: "Protein GPS2" EXACT [UniProtKB:Q13227] xref: EMBL:AAB60432.1 xref: EMBL:AAH13652.1 xref: EMBL:CAB59255.1 xref: EMBL:CAB75677.2 xref: UniProtKB:Q13227 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004723 ! GPS2_human relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005723 ! atf4-gps2 physical interaction relationship: participates_in CCO:I0005914 ! gps2-tak1l physical interaction relationship: participates_in CCO:I0007891 ! tak1l-gps2 physical interaction relationship: participates_in CCO:I0008111 ! gps2-chd3 physical interaction relationship: participates_in CCO:I0008112 ! gps2-setdb1 physical interaction relationship: participates_in CCO:I0008176 ! pbk-gps2 physical interaction relationship: participates_in CCO:I0008234 ! flj20364-gps2 physical interaction relationship: participates_in CCO:I0008393 ! gps2-golga2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000772 ! JNK cascade [Term] id: CCO:B0001747 name: KGP2_HUMAN def: "cGMP-dependent protein kinase 2" [UniProtKB:Q13237] synonym: "CGK 2" EXACT [UniProtKB:Q13237] synonym: "cGKII" EXACT [UniProtKB:Q13237] synonym: "EC 2.7.11.12" EXACT [UniProtKB:Q13237] synonym: "Type II cGMP-dependent protein kinase" EXACT [UniProtKB:Q13237] xref: EMBL:BAA18934.1 xref: EMBL:CAA64318.1 xref: EMBL:CAA76073.1 xref: UniProtKB:O00125 xref: UniProtKB:O60916 xref: UniProtKB:Q13237 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004936 ! PRKG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012513 ! KGP2_HUMAN-Nitrated tyrosine354 [Term] id: CCO:B0001748 name: MD2L1_HUMAN def: "Mitotic spindle assembly checkpoint protein MAD2A" [UniProtKB:Q13257] synonym: "HsMAD2" EXACT [UniProtKB:Q13257] synonym: "MAD2-like 1" EXACT [UniProtKB:Q13257] xref: EMBL:AAC50781.1 xref: EMBL:AAC52060.1 xref: EMBL:AAH00356.1 xref: EMBL:AAH05945.1 xref: EMBL:BAB63410.1 xref: EMBL:CAA03943.1 xref: UniProtKB:Q13257 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005048 ! MAD2L1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005802 ! mad2l1-tsc22d4 physical interaction relationship: participates_in CCO:I0005960 ! mad1l1-mad2l1 physical interaction relationship: participates_in CCO:I0006415 ! tnfrsf1b-mad2l1 physical interaction relationship: participates_in CCO:I0006448 ! zwint_mad2l1_1 colocalization relationship: participates_in CCO:I0006988 ! adam17-mad2l1-1 physical interaction relationship: participates_in CCO:I0006989 ! adam17-mad2l1-3 physical interaction relationship: participates_in CCO:I0007360 ! adam17-mad2l1-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041159 ! MD2L1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0001749 name: SKP2_HUMAN def: "S-phase kinase-associated protein 2" [UniProtKB:Q13309] synonym: "Cyclin A/CDK2-associated protein p45" EXACT [UniProtKB:Q13309] synonym: "F-box protein Skp2" EXACT [UniProtKB:Q13309] synonym: "F-box/LRR-repeat protein 1" EXACT [UniProtKB:Q13309] synonym: "p45skp2" EXACT [UniProtKB:Q13309] xref: EMBL:AAC50242.1 xref: EMBL:AAH01441.1 xref: EMBL:AAH07441.1 xref: EMBL:AAK31593.1 xref: EMBL:BAB87200.1 xref: EMBL:BAB87201.1 xref: EMBL:BAB87202.1 xref: UniProtKB:Q13309 xref: UniProtKB:Q8TDZ0 xref: UniProtKB:Q8TDZ1 xref: UniProtKB:Q9BV69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005623 ! SKP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006197 ! orc1-skp2-2 physical interaction relationship: participates_in CCO:I0006695 ! cul1-skp1-1 physical interaction relationship: participates_in CCO:I0006746 ! dusp1-skp2-1 physical interaction relationship: participates_in CCO:I0006747 ! dusp1-skp2-2 physical interaction relationship: participates_in CCO:I0006767 ! skp1a-skp2-1 direct interaction relationship: participates_in CCO:I0006768 ! skp1a-skp2-2 direct interaction relationship: participates_in CCO:I0006769 ! skp1a-skp2-3 direct interaction relationship: participates_in CCO:I0006785 ! myc-skp2 physical interaction relationship: participates_in CCO:I0006797 ! cul1-cul1-7 physical interaction relationship: participates_in CCO:I0006863 ! cul1-skp1-5 physical interaction relationship: participates_in CCO:I0006864 ! cul1-skp2-2 physical interaction relationship: participates_in CCO:I0007105 ! cul1-skp2 physical interaction relationship: participates_in CCO:I0007110 ! cul1-skp1 physical interaction relationship: participates_in CCO:I0007111 ! cul1-skp1-4 physical interaction relationship: participates_in CCO:I0007112 ! cul1-skp2-1 physical interaction relationship: participates_in CCO:I0007149 ! dusp1-skp2-3 physical interaction relationship: participates_in CCO:I0007188 ! myc-skp2-1 physical interaction relationship: participates_in CCO:I0007533 ! cdt1-cdk2-1 physical interaction relationship: participates_in CCO:I0007537 ! orc1-skp2-1 physical interaction relationship: participates_in CCO:I0007731 ! skp2-cks1-1 physical interaction relationship: participates_in CCO:I0007732 ! skp2-cks1-2 physical interaction relationship: participates_in CCO:I0007733 ! skp2-cks1-4 physical interaction relationship: participates_in CCO:I0007846 ! skp2-cks1-3 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0014067 ! SKP2_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0048393 ! SKP2_HUMAN-Phosphoserine179 [Term] id: CCO:B0001750 name: ATM_HUMAN def: "Serine-protein kinase ATM" [UniProtKB:Q13315] synonym: "A-T, mutated" EXACT [UniProtKB:Q13315] synonym: "Ataxia telangiectasia mutated" EXACT [UniProtKB:Q13315] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13315] xref: EMBL:AAA86520.1 xref: EMBL:AAB38309.1 xref: EMBL:AAB38310.1 xref: EMBL:AAB65827.1 xref: EMBL:AAC50289.1 xref: EMBL:AAC51298.1 xref: EMBL:AAO26044.1 xref: EMBL:CAA62603.1 xref: UniProtKB:O15429 xref: UniProtKB:Q12758 xref: UniProtKB:Q13315 xref: UniProtKB:Q16551 xref: UniProtKB:Q93007 xref: UniProtKB:Q9NP02 xref: UniProtKB:Q9UCX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004117 ! ATM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006252 ! atm-aatf-1 phosphorylation relationship: participates_in CCO:I0006256 ! atm-aatf-2 phosphorylation relationship: participates_in CCO:I0006960 ! mdc1-atm-1 physical interaction relationship: participates_in CCO:I0006962 ! nbs1-atm-1 physical interaction relationship: participates_in CCO:I0007696 ! atm-cabl-1 physical interaction relationship: participates_in CCO:I0007697 ! atm-pin2_trf1-1 physical interaction relationship: participates_in CCO:I0007698 ! pin2_trf1-atm-2 physical interaction relationship: participates_in CCO:I0007945 ! atm-aatf physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000105 ! mitotic cell cycle spindle assembly checkpoint relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010653 ! ATM_HUMAN-Phosphothreonine72 relationship: transforms_into CCO:B0010654 ! ATM_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0010655 ! ATM_HUMAN-Phosphothreonine86 relationship: transforms_into CCO:B0010656 ! ATM_HUMAN-Phosphoserine367 relationship: transforms_into CCO:B0010657 ! ATM_HUMAN-Phosphothreonine373 relationship: transforms_into CCO:B0010658 ! ATM_HUMAN-Phosphoserine1981 relationship: transforms_into CCO:B0010659 ! ATM_HUMAN-Phosphothreonine1985 [Term] id: CCO:B0001751 name: CD5R2_HUMAN def: "Cyclin-dependent kinase 5 activator 2 precursor" [UniProtKB:Q13319] synonym: "CDK5 activator 2" EXACT [UniProtKB:Q13319] synonym: "Cyclin-dependent kinase 5 regulatory subunit 2" EXACT [UniProtKB:Q13319] synonym: "P39" EXACT [UniProtKB:Q13319] synonym: "P39I" EXACT [UniProtKB:Q13319] xref: EMBL:AAC50278.1 xref: EMBL:AAX88916.1 xref: EMBL:ABB96255.1 xref: UniProtKB:Q13319 xref: UniProtKB:Q4ZFW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004281 ! CDK5R2_human relationship: has_function CCO:F0003202 ! cyclin-dependent protein kinase 5 activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000803 ! cyclin-dependent protein kinase 5 activator complex relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity [Term] id: CCO:B0001752 name: UB2V1_HUMAN def: "Ubiquitin-conjugating enzyme E2 variant 1" [UniProtKB:Q13404] synonym: "CROC-1" EXACT [UniProtKB:Q13404] synonym: "TRAF6-regulated IKK activator 1 beta Uev1A" EXACT [UniProtKB:Q13404] synonym: "UEV-1" EXACT [UniProtKB:Q13404] xref: EMBL:AAB72015.1 xref: EMBL:AAB72016.1 xref: EMBL:AAC02755.1 xref: EMBL:AAC02756.1 xref: EMBL:AAC02757.1 xref: EMBL:AAC02780.1 xref: EMBL:AAG24229.1 xref: EMBL:AAH00468.1 xref: EMBL:AAH08944.2 xref: EMBL:AAP36046.1 xref: EMBL:CAB76864.1 xref: EMBL:CAB76865.1 xref: EMBL:CAC16954.1 xref: EMBL:CAC16955.1 xref: UniProtKB:Q13403 xref: UniProtKB:Q13404 xref: UniProtKB:Q13532 xref: UniProtKB:Q96H34 xref: UniProtKB:Q9GZT0 xref: UniProtKB:Q9GZW1 xref: UniProtKB:Q9H4J3 xref: UniProtKB:Q9H4J4 xref: UniProtKB:Q9UKL1 xref: UniProtKB:Q9UM48 xref: UniProtKB:Q9UM49 xref: UniProtKB:Q9UM50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005854 ! UBE2V1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001219 ! ubiquitin conjugating enzyme complex relationship: participates_in CCO:P0000643 ! regulation of DNA repair relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0001753 name: TOP3A_HUMAN def: "DNA topoisomerase 3-alpha" [UniProtKB:Q13472] synonym: "DNA topoisomerase III alpha" EXACT [UniProtKB:Q13472] synonym: "EC 5.99.1.2" EXACT [UniProtKB:Q13472] xref: EMBL:AAB03694.1 xref: EMBL:AAB03695.1 xref: EMBL:AAH51748.1 xref: UniProtKB:Q13472 xref: UniProtKB:Q13473 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005812 ! TOP3A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000419 ! DNA topoisomerase activity relationship: has_function CCO:F0000420 ! DNA topoisomerase type I activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:I0007422 ! blm-c9orf76-2 physical interaction relationship: participates_in CCO:I0007427 ! c9orf76-blm-2 physical interaction relationship: participates_in CCO:I0007748 ! c9orf76-blm-1 physical interaction relationship: participates_in CCO:I0007749 ! blm-c9orf76-1 physical interaction relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: transforms_into CCO:B0071452 ! TOP3A_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0071453 ! TOP3A_HUMAN-Phosphoserine771 [Term] id: CCO:B0001754 name: TBB3_HUMAN def: "Tubulin beta-3 chain" [UniProtKB:Q13509] synonym: "Tubulin beta-4" EXACT [UniProtKB:Q13509] synonym: "Tubulin beta-III" EXACT [UniProtKB:Q13509] xref: EMBL:AAC52035.1 xref: EMBL:AAH00748.1 xref: EMBL:AAH03021.2 xref: EMBL:AAL28094.1 xref: UniProtKB:Q13509 xref: UniProtKB:Q9BTZ0 xref: UniProtKB:Q9BW10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005735 ! TUBB3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0006383 ! map3k3-tubb4 physical interaction relationship: participates_in CCO:I0007844 ! stau-dhx9-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001755 name: PIN1_HUMAN def: "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1" [UniProtKB:Q13526] synonym: "EC 5.2.1.8" EXACT [UniProtKB:Q13526] synonym: "PPIase Pin1" EXACT [UniProtKB:Q13526] synonym: "Rotamase Pin1" EXACT [UniProtKB:Q13526] xref: EMBL:AAC50492.1 xref: EMBL:AAH02899.1 xref: EMBL:AAV38138.1 xref: EMBL:CAG28582.1 xref: UniProtKB:Q13526 xref: UniProtKB:Q53X75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005316 ! PIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005737 ! pin1-traf2 physical interaction relationship: participates_in CCO:I0005745 ! pin1-tsc22d4 physical interaction relationship: participates_in CCO:I0005749 ! pin1-rai1 physical interaction relationship: participates_in CCO:I0005757 ! gga2-pin1 physical interaction relationship: participates_in CCO:I0005778 ! pin1-zimp7 physical interaction relationship: participates_in CCO:I0005810 ! mdfi-pin1 physical interaction relationship: participates_in CCO:I0005874 ! hnrpc-pin1 physical interaction relationship: participates_in CCO:I0005881 ! pin1-rbpms physical interaction relationship: participates_in CCO:I0005891 ! pin1-rbbp8 physical interaction relationship: participates_in CCO:I0005915 ! nono-pin1 physical interaction relationship: participates_in CCO:I0006459 ! pin1-nek6-1 physical interaction relationship: participates_in CCO:I0006552 ! cdk2-pin1-3 physical interaction relationship: participates_in CCO:I0006642 ! pin1-ubqln4 physical interaction relationship: participates_in CCO:I0007509 ! pin1-nek6-2 physical interaction relationship: participates_in CCO:I0007510 ! pin1-nek6-3 colocalization relationship: participates_in CCO:I0008165 ! socs3-pin1 physical interaction relationship: participates_in CCO:I0008218 ! ddx24-pin1 physical interaction relationship: participates_in CCO:I0008259 ! lepr-pin1 physical interaction relationship: participates_in CCO:I0008353 ! klhlx-pin1 physical interaction relationship: participates_in CCO:I0008392 ! gpaa1-pin1 physical interaction relationship: participates_in CCO:I0008423 ! ptov1-pin1 physical interaction relationship: participates_in CCO:I0008447 ! zcchc10-pin1 physical interaction relationship: participates_in CCO:I0008462 ! css2-pin1 physical interaction relationship: participates_in CCO:I0008463 ! mtfr1-pin1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: transforms_into CCO:B0013514 ! PIN1_HUMAN-Phosphoserine108 [Term] id: CCO:B0001756 name: ATR_HUMAN def: "Serine/threonine-protein kinase ATR" [UniProtKB:Q13535] synonym: "Ataxia telangiectasia and Rad3-related protein" EXACT [UniProtKB:Q13535] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13535] synonym: "FRAP-related protein 1" EXACT [UniProtKB:Q13535] xref: EMBL:AAC50405.1 xref: EMBL:AAC50929.1 xref: EMBL:AAK26749.1 xref: EMBL:CAA70298.1 xref: UniProtKB:Q13535 xref: UniProtKB:Q7KYL3 xref: UniProtKB:Q93051 xref: UniProtKB:Q9BXK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004124 ! ATR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0004985 ! MutLalpha complex binding relationship: has_function CCO:F0004987 ! MutSalpha complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0006253 ! atr-aatf-2 phosphorylation relationship: participates_in CCO:I0006900 ! atr-tp53-1 phosphorylation relationship: participates_in CCO:I0006907 ! atr-creb1-1 phosphorylation relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: transforms_into CCO:B0010709 ! ATR_HUMAN-Phosphoserine919 relationship: transforms_into CCO:B0063660 ! ATR_HUMAN-Phosphothreonine1989 [Term] id: CCO:B0001757 name: PKD2_HUMAN def: "Polycystin-2" [UniProtKB:Q13563] synonym: "Autosomal dominant polycystic kidney disease type II protein" EXACT [UniProtKB:Q13563] synonym: "Polycystic kidney disease 2 protein" EXACT [UniProtKB:Q13563] synonym: "Polycystwin" EXACT [UniProtKB:Q13563] synonym: "R48321" EXACT [UniProtKB:Q13563] xref: EMBL:AAC16004.1 xref: EMBL:AAC50520.1 xref: EMBL:AAC50933.1 xref: EMBL:AAI12262.1 xref: EMBL:AAI12264.1 xref: UniProtKB:O60441 xref: UniProtKB:Q13563 xref: UniProtKB:Q15764 xref: UniProtKB:Q2M1Q3 xref: UniProtKB:Q2M1Q5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005324 ! PKD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: transforms_into CCO:B0013540 ! PKD2_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0013541 ! PKD2_HUMAN-Phosphoserine254 relationship: transforms_into CCO:B0013542 ! PKD2_HUMAN-Phosphothreonine260 relationship: transforms_into CCO:B0013543 ! PKD2_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0013544 ! PKD2_HUMAN-Phosphoserine852 relationship: transforms_into CCO:B0013545 ! PKD2_HUMAN-Phosphoserine858 [Term] id: CCO:B0001758 name: ULA1_HUMAN def: "NEDD8-activating enzyme E1 regulatory subunit" [UniProtKB:Q13564] synonym: "Amyloid beta precursor protein-binding protein 1, 59 kDa" EXACT [UniProtKB:Q13564] synonym: "Amyloid protein-binding protein 1" EXACT [UniProtKB:Q13564] synonym: "APP-BP1" EXACT [UniProtKB:Q13564] synonym: "Proto-oncogene protein 1" EXACT [UniProtKB:Q13564] xref: EMBL:AAC23784.1 xref: EMBL:AAC50477.1 xref: EMBL:AAH00480.1 xref: EMBL:AAH13301.1 xref: EMBL:AAP35030.1 xref: EMBL:CAB66732.1 xref: UniProtKB:Q13564 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006428 ! NAE1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004164 ! NEDD8 activating enzyme activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005976 ! nedd8-tp53-1 neddylation relationship: participates_in CCO:I0007022 ! appbp1-nedd8-1 physical interaction relationship: participates_in CCO:I0007023 ! appbp1-nedd8-2 physical interaction relationship: participates_in CCO:I0008363 ! ubqln4-appbp1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000187 ! S-M checkpoint relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0001759 name: CUL1_HUMAN def: "Cullin-1" [UniProtKB:Q13616] synonym: "CUL-1" EXACT [UniProtKB:Q13616] xref: EMBL:AAC36681.1 xref: EMBL:AAC50544.1 xref: EMBL:AAI25120.1 xref: EMBL:AAI25121.1 xref: EMBL:AAM49153.1 xref: EMBL:CAD97651.1 xref: UniProtKB:O60719 xref: UniProtKB:Q08AL6 xref: UniProtKB:Q13616 xref: UniProtKB:Q8IYW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004421 ! CUL1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000850 ! SCF ubiquitin ligase complex relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: participates_in CCO:I0006024 ! cul1-cand1 physical interaction relationship: participates_in CCO:I0006242 ! fbxo25-cul1-1 physical interaction relationship: participates_in CCO:I0006243 ! fbxo4-cul1-2 physical interaction relationship: participates_in CCO:I0006244 ! fbxo7-cul1-1 physical interaction relationship: participates_in CCO:I0006308 ! cul1-cand1-4 physical interaction relationship: participates_in CCO:I0006309 ! cul1-cand1-5 physical interaction relationship: participates_in CCO:I0006310 ! cul1-cand1-6 physical interaction relationship: participates_in CCO:I0006685 ! cul1-tip120a-1 physical interaction relationship: participates_in CCO:I0006688 ! cul1-tip120a-2 physical interaction relationship: participates_in CCO:I0006693 ! cul1-tip120a-3 physical interaction relationship: participates_in CCO:I0006694 ! cul1-tip120a-4 physical interaction relationship: participates_in CCO:I0006695 ! cul1-skp1-1 physical interaction relationship: participates_in CCO:I0006696 ! cul1-skp1-2 physical interaction relationship: participates_in CCO:I0006697 ! cul1-skp1-3 physical interaction relationship: participates_in CCO:I0006747 ! dusp1-skp2-2 physical interaction relationship: participates_in CCO:I0006796 ! cul1-rbx1-6 direct interaction relationship: participates_in CCO:I0006797 ! cul1-cul1-7 physical interaction relationship: participates_in CCO:I0006863 ! cul1-skp1-5 physical interaction relationship: participates_in CCO:I0006864 ! cul1-skp2-2 physical interaction relationship: participates_in CCO:I0006865 ! cand1-cul1-3 physical interaction relationship: participates_in CCO:I0006866 ! cul1-cand1-7 physical interaction relationship: participates_in CCO:I0006867 ! cul1-rbx1-5 physical interaction relationship: participates_in CCO:I0007105 ! cul1-skp2 physical interaction relationship: participates_in CCO:I0007106 ! cul1-cand1-1 physical interaction relationship: participates_in CCO:I0007107 ! cand1-cul1 physical interaction relationship: participates_in CCO:I0007108 ! cand1-cul1-1 physical interaction relationship: participates_in CCO:I0007109 ! cul1-cand1-2 physical interaction relationship: participates_in CCO:I0007110 ! cul1-skp1 physical interaction relationship: participates_in CCO:I0007111 ! cul1-skp1-4 physical interaction relationship: participates_in CCO:I0007112 ! cul1-skp2-1 physical interaction relationship: participates_in CCO:I0007113 ! cand1-cul1-4 physical interaction relationship: participates_in CCO:I0007114 ! cul1-cand1-8 physical interaction relationship: participates_in CCO:I0007254 ! cand1-cul1-2 physical interaction relationship: participates_in CCO:I0007504 ! cand1-cul1-5 physical interaction relationship: participates_in CCO:I0007943 ! fbxo11-skp1-1 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals [Term] id: CCO:B0001760 name: CUL2_HUMAN def: "Cullin-2" [UniProtKB:Q13617] synonym: "CUL-2" EXACT [UniProtKB:Q13617] xref: EMBL:AAC50545.1 xref: EMBL:AAC51190.1 xref: EMBL:AAD23581.1 xref: EMBL:AAH09591.1 xref: EMBL:AAI10902.1 xref: EMBL:CAI13163.1 xref: UniProtKB:O00200 xref: UniProtKB:Q13617 xref: UniProtKB:Q5T2B6 xref: UniProtKB:Q9UNF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004422 ! CUL2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: participates_in CCO:I0006686 ! cul2-tip120a-2 physical interaction relationship: participates_in CCO:I0006689 ! cul2-tip120a-1 physical interaction relationship: participates_in CCO:I0007103 ! cul2-cand1 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: transforms_into CCO:B0011411 ! CUL2_HUMAN-Phosphotyrosine394 relationship: transforms_into CCO:B0064588 ! CUL2_HUMAN-Phosphothreonine661 [Term] id: CCO:B0001761 name: CUL3_HUMAN def: "Cullin-3" [UniProtKB:Q13618] synonym: "CUL-3" EXACT [UniProtKB:Q13618] xref: EMBL:AAC28621.1 xref: EMBL:AAC36304.1 xref: EMBL:AAC36682.1 xref: EMBL:AAC50546.1 xref: EMBL:AAH31844.1 xref: EMBL:AAH39598.1 xref: EMBL:AAH92409.1 xref: EMBL:AAQ01660.1 xref: EMBL:BAA31592.2 xref: UniProtKB:O75415 xref: UniProtKB:Q13618 xref: UniProtKB:Q569L3 xref: UniProtKB:Q9UBI8 xref: UniProtKB:Q9UET7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004423 ! CUL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006684 ! cul3-tip120a-2 physical interaction relationship: participates_in CCO:I0006690 ! cul3-tip120a-1 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: transforms_into CCO:B0011412 ! CUL3_HUMAN-Phosphotyrosine58 relationship: transforms_into CCO:B0011413 ! CUL3_HUMAN-Phosphoserine737 relationship: transforms_into CCO:B0048215 ! CUL3_HUMAN-Phosphoserine450 [Term] id: CCO:B0001762 name: CUL4A_HUMAN def: "Cullin-4A" [UniProtKB:Q13619] synonym: "CUL-4A" EXACT [UniProtKB:Q13619] xref: EMBL:AAC50547.1 xref: EMBL:AAD45191.1 xref: EMBL:AAH08308.2 xref: EMBL:AAR13072.1 xref: EMBL:BAA33146.1 xref: EMBL:BAD93235.1 xref: EMBL:CAI13795.1 xref: UniProtKB:O75834 xref: UniProtKB:Q13619 xref: UniProtKB:Q589T6 xref: UniProtKB:Q5TC62 xref: UniProtKB:Q6UP08 xref: UniProtKB:Q9UP17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004424 ! CUL4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006683 ! cul4a-tip120a-1 physical interaction relationship: participates_in CCO:I0006691 ! cul4a-tip120a-2 physical interaction relationship: participates_in CCO:I0006811 ! cul4a-ddb2 physical interaction relationship: participates_in CCO:I0006812 ! cul4a-cul4b physical interaction relationship: participates_in CCO:I0006813 ! cul4a-eed physical interaction relationship: participates_in CCO:I0006814 ! cul4a-cul4b-1 physical interaction relationship: participates_in CCO:I0006815 ! cul4a-cul4b-2 physical interaction relationship: participates_in CCO:I0006816 ! cul4a-cul4b-3 physical interaction relationship: participates_in CCO:I0006819 ! rbbp5-cul4a physical interaction relationship: participates_in CCO:I0007104 ! cul4a-cand1 physical interaction relationship: participates_in CCO:I0007514 ! h3_peptide-cul4a physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0007717 ! cul4b-wdr5 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: transforms_into CCO:B0035996 ! CUL4A_HUMAN-Phosphotyrosine227 relationship: transforms_into CCO:B0064589 ! CUL4A_HUMAN-Phosphoserine10 [Term] id: CCO:B0001763 name: CUL4B_HUMAN def: "Cullin-4B" [UniProtKB:Q13620] synonym: "CUL-4B" EXACT [UniProtKB:Q13620] xref: EMBL:AAB67315.1 xref: EMBL:AAC50548.1 xref: EMBL:AAH36216.1 xref: EMBL:AAK16812.1 xref: EMBL:AAR13073.1 xref: EMBL:BAA31670.2 xref: EMBL:CAD97843.1 xref: UniProtKB:Q13620 xref: UniProtKB:Q6PIE4 xref: UniProtKB:Q6UP07 xref: UniProtKB:Q7Z673 xref: UniProtKB:Q9BY37 xref: UniProtKB:Q9UEB7 xref: UniProtKB:Q9UED7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004425 ! CUL4B_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: participates_in CCO:I0006682 ! cul4b-tip120a-1 physical interaction relationship: participates_in CCO:I0006687 ! cul4b-tip120a-2 physical interaction relationship: participates_in CCO:I0006692 ! cul4b-tip120a-3 physical interaction relationship: participates_in CCO:I0006808 ! cul4b-ddb1-2 physical interaction relationship: participates_in CCO:I0006809 ! cul4b-tle2 physical interaction relationship: participates_in CCO:I0006810 ! ddb1-ddb2-1 physical interaction relationship: participates_in CCO:I0006812 ! cul4a-cul4b physical interaction relationship: participates_in CCO:I0006813 ! cul4a-eed physical interaction relationship: participates_in CCO:I0006814 ! cul4a-cul4b-1 physical interaction relationship: participates_in CCO:I0006815 ! cul4a-cul4b-2 physical interaction relationship: participates_in CCO:I0006816 ! cul4a-cul4b-3 physical interaction relationship: participates_in CCO:I0006817 ! l2dtl-cul4b physical interaction relationship: participates_in CCO:I0006818 ! tle2-ddb1-1 physical interaction relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0007717 ! cul4b-wdr5 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0064590 ! CUL4B_HUMAN-Phosphothreonine30 relationship: transforms_into CCO:B0064591 ! CUL4B_HUMAN-Phosphothreonine31 relationship: transforms_into CCO:B0064592 ! CUL4B_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0064593 ! CUL4B_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0064594 ! CUL4B_HUMAN-Phosphoserine175 [Term] id: CCO:B0001764 name: ASPP2_HUMAN def: "Apoptosis-stimulating of p53 protein 2" [UniProtKB:Q13625] synonym: "53BP2" EXACT [UniProtKB:Q13625] synonym: "Bbp" EXACT [UniProtKB:Q13625] synonym: "Bcl2-binding protein" EXACT [UniProtKB:Q13625] synonym: "p53-binding protein 2" EXACT [UniProtKB:Q13625] synonym: "p53BP2" EXACT [UniProtKB:Q13625] synonym: "Renal carcinoma antigen NY-REN-51" EXACT [UniProtKB:Q13625] synonym: "Tumor suppressor p53-binding protein 2" EXACT [UniProtKB:Q13625] xref: EMBL:AAA21597.1 xref: EMBL:AAC50557.1 xref: EMBL:AAH46150.1 xref: EMBL:AAH58918.1 xref: EMBL:CAC83012.1 xref: UniProtKB:Q12892 xref: UniProtKB:Q13625 xref: UniProtKB:Q86X75 xref: UniProtKB:Q96KQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004110 ! TP53BP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006668 ! app-tp53bp2-2 physical interaction relationship: participates_in CCO:I0007284 ! app-tp53bp2-1 physical interaction relationship: participates_in CCO:I0007285 ! app-tp53bp2-3 physical interaction relationship: participates_in CCO:I0007467 ! tp53-tp53bp2-1 direct interaction relationship: participates_in CCO:I0007626 ! atxn7-tp53bp2 physical interaction relationship: participates_in CCO:I0008178 ! tp53bp2-eef1a1 physical interaction relationship: participates_in CCO:I0008179 ! tp53bp2-kif5a physical interaction relationship: participates_in CCO:I0008180 ! tp53bp2-ptn physical interaction relationship: participates_in CCO:I0008181 ! tp53bp2-utp14a physical interaction relationship: participates_in CCO:I0008182 ! tp53bp2-unc119 physical interaction relationship: participates_in CCO:I0008343 ! tp53bp2-mrpl20 physical interaction relationship: participates_in CCO:I0008442 ! tp53bp2-usp4 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010631 ! ASPP2_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0010632 ! ASPP2_HUMAN-Phosphoserine698 relationship: transforms_into CCO:B0063631 ! ASPP2_HUMAN-Phosphoserine556 relationship: transforms_into CCO:B0063632 ! ASPP2_HUMAN-Phosphoserine569 [Term] id: CCO:B0001765 name: PTC1_HUMAN def: "Protein patched homolog 1" [UniProtKB:Q13635] synonym: "PTC" EXACT [UniProtKB:Q13635] synonym: "PTC1" EXACT [UniProtKB:Q13635] xref: EMBL:AAC50496.1 xref: EMBL:AAC50550.1 xref: EMBL:CAH73817.1 xref: UniProtKB:Q13463 xref: UniProtKB:Q13635 xref: UniProtKB:Q5VZC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005395 ! PTCH1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001752 ! hedgehog receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000826 ! regulation of smoothened signaling pathway [Term] id: CCO:B0001766 name: RUNX3_HUMAN def: "Runt-related transcription factor 3" [UniProtKB:Q13761] synonym: "Acute myeloid leukemia 2 protein" EXACT [UniProtKB:Q13761] synonym: "CBF-alpha-3" EXACT [UniProtKB:Q13761] synonym: "Core-binding factor subunit alpha-3" EXACT [UniProtKB:Q13761] synonym: "Oncogene AML-2" EXACT [UniProtKB:Q13761] synonym: "PEA2-alpha C" EXACT [UniProtKB:Q13761] synonym: "PEBP2-alpha C" EXACT [UniProtKB:Q13761] synonym: "Polyomavirus enhancer-binding protein 2 alpha C subunit" EXACT [UniProtKB:Q13761] synonym: "SL3-3 enhancer factor 1 alpha C subunit" EXACT [UniProtKB:Q13761] synonym: "SL3/AKV core-binding factor alpha C subunit" EXACT [UniProtKB:Q13761] xref: EMBL:AAA86465.1 xref: EMBL:AAH13362.1 xref: EMBL:CAA18856.1 xref: EMBL:CAA56093.2 xref: EMBL:CAA84541.1 xref: UniProtKB:Q12969 xref: UniProtKB:Q13760 xref: UniProtKB:Q13761 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005547 ! RUNX3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006341 ! aml2-tle1-1 direct interaction relationship: participates_in CCO:I0006551 ! aml2-tle1-2 physical interaction relationship: participates_in CCO:I0007292 ! tle1-aml2-1 physical interaction relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: transforms_into CCO:B0048383 ! RUNX3_HUMAN-Phosphoserine243 [Term] id: CCO:B0001767 name: BMPR2_HUMAN def: "Bone morphogenetic protein receptor type-2 precursor" [UniProtKB:Q13873] synonym: "BMP type II receptor" EXACT [UniProtKB:Q13873] synonym: "BMPR-II" EXACT [UniProtKB:Q13873] synonym: "Bone morphogenetic protein receptor type II" EXACT [UniProtKB:Q13873] synonym: "EC 2.7.11.30" EXACT [UniProtKB:Q13873] xref: EMBL:AAC50105.1 xref: EMBL:AAH52985.1 xref: EMBL:BAA09094.1 xref: EMBL:CAA88759.1 xref: UniProtKB:Q13873 xref: UniProtKB:Q16569 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004173 ! BMPR2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:B0001768 name: Q13876_HUMAN def: "Bone-derived growth factor" [UniProtKB:Q13876] xref: EMBL:AAA89173.1 xref: UniProtKB:Q13876 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005988 ! QSCN6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006643 ! qscn6-ubqln4 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001769 name: TBB2A_HUMAN def: "Tubulin beta-2A chain" [UniProtKB:Q13885] xref: EMBL:AAH01194.1 xref: EMBL:AAH18780.1 xref: EMBL:AAN85571.1 xref: EMBL:CAA56071.1 xref: EMBL:CAD70628.1 xref: EMBL:CAG46756.1 xref: UniProtKB:Q13885 xref: UniProtKB:Q6FGZ8 xref: UniProtKB:Q8IWR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005733 ! TUBB2A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0006604 ! disc1-tubb2-1 physical interaction relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001770 name: NFYC_HUMAN def: "Nuclear transcription factor Y subunit gamma" [UniProtKB:Q13952] synonym: "CAAT-box DNA-binding protein subunit C" EXACT [UniProtKB:Q13952] synonym: "NF-YC" EXACT [UniProtKB:Q13952] synonym: "Nuclear transcription factor Y subunit C" EXACT [UniProtKB:Q13952] synonym: "Transactivator HSM-1/2" EXACT [UniProtKB:Q13952] xref: EMBL:AAC50816.1 xref: EMBL:AAC51669.1 xref: EMBL:AAG28389.1 xref: EMBL:AAH05003.1 xref: EMBL:AAV38884.1 xref: EMBL:BAA12818.1 xref: EMBL:BAA14051.1 xref: EMBL:BAA91100.1 xref: EMBL:CAA99055.1 xref: EMBL:CAI16530.1 xref: EMBL:CAI16531.1 xref: EMBL:CAI16533.1 xref: UniProtKB:Q13952 xref: UniProtKB:Q5T6K8 xref: UniProtKB:Q5T6L1 xref: UniProtKB:Q5TZR6 xref: UniProtKB:Q92869 xref: UniProtKB:Q9HBX1 xref: UniProtKB:Q9NXB5 xref: UniProtKB:Q9UM67 xref: UniProtKB:Q9UML0 xref: UniProtKB:Q9UMT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005191 ! NFYC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000816 ! CCAAT-binding factor complex relationship: participates_in CCO:I0006068 ! nfyb-nfyc-1 direct interaction relationship: participates_in CCO:I0006847 ! cbfa-cbfb-1 physical interaction relationship: participates_in CCO:I0006952 ! cbfa-cbfb physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0001771 name: CD2L5_HUMAN def: "Cell division cycle 2-like protein kinase 5" [UniProtKB:Q14004] synonym: "CDC2-related protein kinase 5" EXACT [UniProtKB:Q14004] synonym: "Cholinesterase-related cell division controller" EXACT [UniProtKB:Q14004] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q14004] xref: EMBL:AAA58424.1 xref: EMBL:AAD54514.1 xref: EMBL:AAS07490.1 xref: EMBL:AAS07491.1 xref: EMBL:AAT74623.1 xref: EMBL:BAB47420.1 xref: EMBL:CAC10400.1 xref: EMBL:CAC10401.1 xref: UniProtKB:Q14004 xref: UniProtKB:Q6DKQ9 xref: UniProtKB:Q75MH4 xref: UniProtKB:Q75MH5 xref: UniProtKB:Q96JN4 xref: UniProtKB:Q9H4A0 xref: UniProtKB:Q9H4A1 xref: UniProtKB:Q9UDR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004275 ! CDC2L5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0011032 ! CD2L5_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0011033 ! CD2L5_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0011034 ! CD2L5_HUMAN-Phosphoserine325 relationship: transforms_into CCO:B0011035 ! CD2L5_HUMAN-Phosphoserine340 relationship: transforms_into CCO:B0011036 ! CD2L5_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0011037 ! CD2L5_HUMAN-Phosphoserine367 relationship: transforms_into CCO:B0011038 ! CD2L5_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0011039 ! CD2L5_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0011040 ! CD2L5_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0011041 ! CD2L5_HUMAN-Phosphoserine400 relationship: transforms_into CCO:B0011042 ! CD2L5_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0011043 ! CD2L5_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0011044 ! CD2L5_HUMAN-Phosphoserine439 relationship: transforms_into CCO:B0011045 ! CD2L5_HUMAN-Phosphoserine441 relationship: transforms_into CCO:B0011046 ! CD2L5_HUMAN-Phosphothreonine442 relationship: transforms_into CCO:B0011047 ! CD2L5_HUMAN-Phosphoserine1066 relationship: transforms_into CCO:B0011048 ! CD2L5_HUMAN-Phosphothreonine1246 relationship: transforms_into CCO:B0048183 ! CD2L5_HUMAN-Phosphoserine1054 relationship: transforms_into CCO:B0064149 ! CD2L5_HUMAN-Phosphoserine349 relationship: transforms_into CCO:B0064150 ! CD2L5_HUMAN-Phosphothreonine871 [Term] id: CCO:B0001772 name: CKAP5_HUMAN def: "Cytoskeleton-associated protein 5" [UniProtKB:Q14008] synonym: "Ch-TOG protein" EXACT [UniProtKB:Q14008] synonym: "Colonic and hepatic tumor over-expressed protein" EXACT [UniProtKB:Q14008] xref: EMBL:AAI20870.1 xref: EMBL:BAA07892.2 xref: EMBL:CAA63212.1 xref: UniProtKB:Q0VAX8 xref: UniProtKB:Q14008 xref: UniProtKB:Q14668 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004363 ! CKAP5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006317 ! tacc1-chtog-8 colocalization relationship: participates_in CCO:I0007314 ! tacc1-ckap5 physical interaction relationship: participates_in CCO:I0007566 ! tacc1-chtog-6 direct interaction relationship: participates_in CCO:I0007871 ! tacc1-chtog-7 physical interaction relationship: participates_in CCO:P0000302 ! spindle pole body organization and biogenesis relationship: transforms_into CCO:B0011243 ! CKAP5_HUMAN-Phosphoserine816 [Term] id: CCO:B0001774 name: TOB2_HUMAN def: "Protein Tob2" [UniProtKB:Q14106] synonym: "Protein Tob4" EXACT [UniProtKB:Q14106] synonym: "Transducer of erbB-2 2" EXACT [UniProtKB:Q14106] xref: EMBL:AAH38957.1 xref: EMBL:BAA10971.1 xref: EMBL:BAA87042.1 xref: EMBL:BAB33333.1 xref: EMBL:CAB62938.1 xref: EMBL:CAG30480.1 xref: UniProtKB:Q14106 xref: UniProtKB:Q9BY97 xref: UniProtKB:Q9UBI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005807 ! TOB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001775 name: SEPT6_HUMAN def: "Septin-6" [UniProtKB:Q14141] xref: EMBL:AAH09291.1 xref: EMBL:AAH11922.3 xref: EMBL:AAH36240.1 xref: EMBL:AAK98547.1 xref: EMBL:AAK98548.1 xref: EMBL:AAK98549.1 xref: EMBL:AAK98550.1 xref: EMBL:AAK98551.1 xref: EMBL:BAA09477.1 xref: EMBL:CAI41426.1 xref: UniProtKB:Q14141 xref: UniProtKB:Q5JTK0 xref: UniProtKB:Q969W5 xref: UniProtKB:Q96A13 xref: UniProtKB:Q96GR1 xref: UniProtKB:Q96P86 xref: UniProtKB:Q96P87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005589 ! SEPT6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005780 ! sept1-sept6 physical interaction relationship: participates_in CCO:I0005825 ! sept2-sept6 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013998 ! SEPT6_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013999 ! SEPT6_HUMAN-Phosphoserine408 relationship: transforms_into CCO:B0014000 ! SEPT6_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0014001 ! SEPT6_HUMAN-Phosphoserine416 relationship: transforms_into CCO:B0014002 ! SEPT6_HUMAN-Phosphothreonine418 [Term] id: CCO:B0001776 name: TFDP1_HUMAN def: "Transcription factor Dp-1" [UniProtKB:Q14186] synonym: "DRTF1" EXACT [UniProtKB:Q14186] synonym: "DRTF1-polypeptide 1" EXACT [UniProtKB:Q14186] synonym: "E2F dimerization partner 1" EXACT [UniProtKB:Q14186] xref: EMBL:AAA58440.1 xref: EMBL:AAH11685.1 xref: EMBL:AAN46090.1 xref: EMBL:CAI39789.1 xref: EMBL:EAX09216.1 xref: UniProtKB:Q14186 xref: UniProtKB:Q5JSB4 xref: UniProtKB:Q8IZL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005768 ! TFDP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0005860 ! e2f6-tfdp1 physical interaction relationship: participates_in CCO:P0000014 ! S phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014346 ! TFDP1_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0036034 ! TFDP1_HUMAN-Phosphoserine183 [Term] id: CCO:B0001777 name: TFDP2_HUMAN def: "Transcription factor Dp-2" [UniProtKB:Q14188] synonym: "E2F dimerization partner 2" EXACT [UniProtKB:Q14188] xref: EMBL:AAA69016.1 xref: EMBL:AAB37321.1 xref: EMBL:AAB60378.1 xref: EMBL:AAC50642.1 xref: EMBL:AAH21113.1 xref: EMBL:AAR89905.1 xref: UniProtKB:Q13331 xref: UniProtKB:Q14187 xref: UniProtKB:Q14188 xref: UniProtKB:Q6R754 xref: UniProtKB:Q8WU88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005769 ! TFDP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0005947 ! e2f6-tfdp2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014347 ! TFDP2_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0014348 ! TFDP2_HUMAN-Phosphoserine42 [Term] id: CCO:B0001778 name: BTG3_HUMAN def: "Protein BTG3" [UniProtKB:Q14201] synonym: "Abundant in neuroepithelium area protein" EXACT [UniProtKB:Q14201] synonym: "BTG family member 3" EXACT [UniProtKB:Q14201] synonym: "Protein Tob5" EXACT [UniProtKB:Q14201] xref: EMBL:AAH11957.1 xref: EMBL:BAA33788.1 xref: UniProtKB:Q14201 xref: UniProtKB:Q96ET7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004196 ! BTG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007619 ! atxn1-btg3 physical interaction relationship: participates_in CCO:I0007623 ! atxn1-btg3-1 physical interaction relationship: participates_in CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001779 name: DCTN1_HUMAN def: "Dynactin subunit 1" [UniProtKB:Q14203] synonym: "150 kDa dynein-associated polypeptide" EXACT [UniProtKB:Q14203] synonym: "DAP-150" EXACT [UniProtKB:Q14203] synonym: "DP-150" EXACT [UniProtKB:Q14203] synonym: "p135" EXACT [UniProtKB:Q14203] synonym: "p150-glued" EXACT [UniProtKB:Q14203] xref: EMBL:AAD03694.1 xref: EMBL:AAD55811.1 xref: EMBL:AAD55812.1 xref: EMBL:AAH06163.1 xref: EMBL:AAP35404.1 xref: EMBL:CAA67333.1 xref: UniProtKB:O95296 xref: UniProtKB:Q14203 xref: UniProtKB:Q9BRM9 xref: UniProtKB:Q9UIU1 xref: UniProtKB:Q9UIU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004447 ! DCTN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006800 ! disc1-dctn1 physical interaction relationship: participates_in CCO:I0008466 ! dctn1-pgam1 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0011452 ! DCTN1_HUMAN-Phosphoserine541 [Term] id: CCO:B0001780 name: DYHC1_HUMAN def: "Cytoplasmic dynein 1 heavy chain 1" [UniProtKB:Q14204] synonym: "Cytoplasmic dynein heavy chain 1" EXACT [UniProtKB:Q14204] synonym: "Dynein heavy chain, cytosolic" EXACT [UniProtKB:Q14204] xref: EMBL:AAA16065.1 xref: EMBL:AAB09727.1 xref: EMBL:AAH21297.1 xref: EMBL:AAT74625.1 xref: EMBL:BAA20783.3 xref: UniProtKB:Q14204 xref: UniProtKB:Q6DKQ7 xref: UniProtKB:Q8WU28 xref: UniProtKB:Q92814 xref: UniProtKB:Q9Y4G5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004526 ! DYNC1H1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005696 ! ATPase activity, coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000428 ! cytoplasmic dynein complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000995 ! dynein complex relationship: participates_in CCO:I0006363 ! ikbkg-dnch1 physical interaction relationship: participates_in CCO:I0006579 ! disc1-dnch1 physical interaction relationship: participates_in CCO:I0006580 ! disc1-dnch1-2 physical interaction relationship: participates_in CCO:I0006801 ! disc1-dnch1-1 physical interaction relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: transforms_into CCO:B0032842 ! DYHC1_HUMAN-Phosphoserine2410 relationship: transforms_into CCO:B0032843 ! DYHC1_HUMAN-Phosphotyrosine3379 relationship: transforms_into CCO:B0032844 ! DYHC1_HUMAN-Phosphothreonine4218 relationship: transforms_into CCO:B0032845 ! DYHC1_HUMAN-Phosphothreonine4221 relationship: transforms_into CCO:B0032846 ! DYHC1_HUMAN-Phosphoserine4368 [Term] id: CCO:B0001781 name: E2F2_HUMAN def: "Transcription factor E2F2" [UniProtKB:Q14209] synonym: "E2F-2" EXACT [UniProtKB:Q14209] xref: EMBL:AAA16890.1 xref: EMBL:AAH53676.1 xref: EMBL:AAM54044.1 xref: EMBL:CAA15949.1 xref: UniProtKB:Q14209 xref: UniProtKB:Q7Z6H1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004534 ! E2F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0008361 ! bcar1-e2f2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001782 name: CASL_HUMAN def: "Enhancer of filamentation 1" [UniProtKB:Q14511] synonym: "Cas scaffolding protein family member 2" EXACT [UniProtKB:Q14511] synonym: "CAS-L" EXACT [UniProtKB:Q14511] synonym: "CasL" EXACT [UniProtKB:Q14511] synonym: "CRK-associated substrate-related protein" EXACT [UniProtKB:Q14511] synonym: "hEF1" EXACT [UniProtKB:Q14511] synonym: "NEDD-9" EXACT [UniProtKB:Q14511] synonym: "Neural precursor cell expressed developmentally down-regulated protein 9" EXACT [UniProtKB:Q14511] synonym: "p105" EXACT [UniProtKB:Q14511] synonym: "Renal carcinoma antigen NY-REN-12" EXACT [UniProtKB:Q14511] xref: EMBL:AAA98770.1 xref: EMBL:AAB53696.1 xref: EMBL:AAH40207.1 xref: EMBL:CAI21579.1 xref: EMBL:CAI22676.1 xref: EMBL:EAW55301.1 xref: UniProtKB:Q14511 xref: UniProtKB:Q5T9R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004221 ! NEDD9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010924 ! CASL_HUMAN-Phosphotyrosine12 relationship: transforms_into CCO:B0010925 ! CASL_HUMAN-Phosphotyrosine92 relationship: transforms_into CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: transforms_into CCO:B0010927 ! CASL_HUMAN-Phosphotyrosine177 relationship: transforms_into CCO:B0010928 ! CASL_HUMAN-Phosphotyrosine189 relationship: transforms_into CCO:B0064071 ! CASL_HUMAN-Phosphotyrosine317 relationship: transforms_into CCO:B0064072 ! CASL_HUMAN-Phosphotyrosine345 [Term] id: CCO:B0001783 name: HIC1_HUMAN def: "Hypermethylated in cancer 1 protein" [UniProtKB:Q14526] synonym: "Hic-1" EXACT [UniProtKB:Q14526] synonym: "Zinc finger and BTB domain-containing protein 29" EXACT [UniProtKB:Q14526] xref: EMBL:AAD09201.1 xref: UniProtKB:Q14526 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004805 ! HIC1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012189 ! HIC1_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0012190 ! HIC1_HUMAN-N6-acetyllysine333 [Term] id: CCO:B0001784 name: DMC1_HUMAN def: "Meiotic recombination protein DMC1/LIM15 homolog" [UniProtKB:Q14565] xref: EMBL:AAI25164.1 xref: EMBL:AAI25165.1 xref: EMBL:AAR89915.1 xref: EMBL:BAA09932.1 xref: EMBL:BAA10970.1 xref: EMBL:CAB45656.1 xref: EMBL:CAG30372.1 xref: UniProtKB:Q08AI1 xref: UniProtKB:Q14565 xref: UniProtKB:Q99498 xref: UniProtKB:Q9UH11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004485 ! DMC1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0001785 name: MCM6_HUMAN def: "DNA replication licensing factor MCM6" [UniProtKB:Q14566] synonym: "p105MCM" EXACT [UniProtKB:Q14566] xref: EMBL:AAB48165.1 xref: EMBL:AAC50766.1 xref: EMBL:AAH32374.1 xref: EMBL:AAO26043.1 xref: EMBL:BAA12699.1 xref: UniProtKB:Q13504 xref: UniProtKB:Q14566 xref: UniProtKB:Q99859 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005041 ! MCM6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005763 ! il1f5-mcm6 physical interaction relationship: participates_in CCO:I0005827 ! mcm6-psma1 physical interaction relationship: participates_in CCO:I0005833 ! mcm6-scnm1 physical interaction relationship: participates_in CCO:I0005883 ! ing5-mcm6 physical interaction relationship: participates_in CCO:I0005918 ! mcm6-mllt3 physical interaction relationship: participates_in CCO:I0005949 ! mcm2-mcm6 physical interaction relationship: participates_in CCO:I0005958 ! mcm6-mcm6-1 physical interaction relationship: participates_in CCO:I0005967 ! mcm6-smc1-1 physical interaction relationship: participates_in CCO:I0005968 ! mcm6-mcm7-1 physical interaction relationship: participates_in CCO:I0006081 ! orc6l-mcm6 direct interaction relationship: participates_in CCO:I0006085 ! mcm10-mcm6 direct interaction relationship: participates_in CCO:I0006103 ! mcm6-mcm6 direct interaction relationship: participates_in CCO:I0006114 ! mcm6-ccna1 direct interaction relationship: participates_in CCO:I0006121 ! mcm6-gmnn direct interaction relationship: participates_in CCO:I0006163 ! mcm3-mcm6 direct interaction relationship: participates_in CCO:I0007542 ! mcm4-mcm6-1 physical interaction relationship: participates_in CCO:I0007914 ! mcm2-7_human physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012836 ! MCM6_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0012837 ! MCM6_HUMAN-Phosphoserine762 relationship: transforms_into CCO:B0012838 ! MCM6_HUMAN-Phosphothreonine791 [Term] id: CCO:B0001786 name: Q14569_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q14569] xref: EMBL:AAB59556.1 xref: UniProtKB:Q14569 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001787 name: ESPL1_HUMAN def: "Separin" [UniProtKB:Q14674] synonym: "Caspase-like protein ESPL1" EXACT [UniProtKB:Q14674] synonym: "EC 3.4.22.49" EXACT [UniProtKB:Q14674] synonym: "Extra spindle poles-like 1 protein" EXACT [UniProtKB:Q14674] synonym: "Separase" EXACT [UniProtKB:Q14674] xref: EMBL:AAR18247.1 xref: EMBL:BAA11482.2 xref: UniProtKB:Q14674 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004589 ! ESPL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000225 ! establishment of mitotic spindle localization relationship: participates_in CCO:P0000253 ! positive regulation of mitotic metaphase/anaphase transition relationship: participates_in CCO:P0000254 ! negative regulation of sister chromatid cohesion relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: transforms_into CCO:B0011766 ! ESPL1_HUMAN-Phosphoserine1126 relationship: transforms_into CCO:B0011767 ! ESPL1_HUMAN-Phosphoserine1508 relationship: transforms_into CCO:B0065161 ! ESPL1_HUMAN-Phosphoserine1396 relationship: transforms_into CCO:B0065162 ! ESPL1_HUMAN-Phosphoserine1399 [Term] id: CCO:B0001788 name: MDC1_HUMAN def: "Mediator of DNA damage checkpoint protein 1" [UniProtKB:Q14676] synonym: "Nuclear factor with BRCT domains 1" EXACT [UniProtKB:Q14676] xref: EMBL:AAI10646.1 xref: EMBL:AAI31492.1 xref: EMBL:AAI52557.1 xref: EMBL:BAA11487.2 xref: EMBL:BAB63322.1 xref: EMBL:BAC54931.1 xref: EMBL:BAE78617.1 xref: EMBL:BAF31266.1 xref: EMBL:CAH18685.1 xref: EMBL:CAI17440.1 xref: EMBL:CAI18195.1 xref: EMBL:CAI41890.1 xref: EMBL:CAI41891.1 xref: EMBL:CAM24847.1 xref: EMBL:CAM25512.1 xref: EMBL:CAM25928.1 xref: EMBL:CAM25929.1 xref: EMBL:CAQ06769.1 xref: EMBL:CAQ06770.1 xref: EMBL:CAQ06813.1 xref: EMBL:CAQ06814.1 xref: EMBL:CAQ07571.1 xref: EMBL:CAQ07572.1 xref: EMBL:CAQ08690.1 xref: EMBL:CAQ08691.1 xref: EMBL:EAX03321.1 xref: UniProtKB:A2AB04 xref: UniProtKB:A2BF04 xref: UniProtKB:A2RRA8 xref: UniProtKB:A7YY86 xref: UniProtKB:B0S8A2 xref: UniProtKB:Q0EFC2 xref: UniProtKB:Q14676 xref: UniProtKB:Q2L6H7 xref: UniProtKB:Q2TAZ4 xref: UniProtKB:Q5JP55 xref: UniProtKB:Q5JP56 xref: UniProtKB:Q5ST83 xref: UniProtKB:Q68CQ3 xref: UniProtKB:Q86Z06 xref: UniProtKB:Q96QC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005050 ! MDC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006960 ! mdc1-atm-1 physical interaction relationship: participates_in CCO:I0006961 ! nbs1-mdc1-1 physical interaction relationship: participates_in CCO:I0006962 ! nbs1-atm-1 physical interaction relationship: participates_in CCO:I0007131 ! terf2ip-rad50 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0012848 ! MDC1_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0012849 ! MDC1_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0012850 ! MDC1_HUMAN-Phosphothreonine331 relationship: transforms_into CCO:B0012851 ! MDC1_HUMAN-Phosphoserine372 relationship: transforms_into CCO:B0012852 ! MDC1_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0012853 ! MDC1_HUMAN-Phosphothreonine378 relationship: transforms_into CCO:B0012854 ! MDC1_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0012855 ! MDC1_HUMAN-Phosphothreonine404 relationship: transforms_into CCO:B0012856 ! MDC1_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0012857 ! MDC1_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0012858 ! MDC1_HUMAN-Phosphothreonine455 relationship: transforms_into CCO:B0012859 ! MDC1_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0012860 ! MDC1_HUMAN-Phosphoserine498 relationship: transforms_into CCO:B0012861 ! MDC1_HUMAN-Phosphoserine513 relationship: transforms_into CCO:B0012862 ! MDC1_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0012863 ! MDC1_HUMAN-Phosphothreonine523 relationship: transforms_into CCO:B0012864 ! MDC1_HUMAN-Phosphothreonine652 relationship: transforms_into CCO:B0012865 ! MDC1_HUMAN-Phosphothreonine659 relationship: transforms_into CCO:B0012866 ! MDC1_HUMAN-Phosphoserine763 relationship: transforms_into CCO:B0012867 ! MDC1_HUMAN-Phosphothreonine765 relationship: transforms_into CCO:B0012868 ! MDC1_HUMAN-Phosphoserine780 relationship: transforms_into CCO:B0012869 ! MDC1_HUMAN-Phosphoserine882 relationship: transforms_into CCO:B0012870 ! MDC1_HUMAN-Phosphoserine955 relationship: transforms_into CCO:B0012871 ! MDC1_HUMAN-Phosphoserine964 relationship: transforms_into CCO:B0012872 ! MDC1_HUMAN-Phosphoserine986 relationship: transforms_into CCO:B0012873 ! MDC1_HUMAN-Phosphoserine988 relationship: transforms_into CCO:B0012874 ! MDC1_HUMAN-Phosphoserine995 relationship: transforms_into CCO:B0012875 ! MDC1_HUMAN-Phosphoserine1068 relationship: transforms_into CCO:B0012876 ! MDC1_HUMAN-Phosphoserine1086 relationship: transforms_into CCO:B0012877 ! MDC1_HUMAN-Phosphoserine1095 relationship: transforms_into CCO:B0012878 ! MDC1_HUMAN-Phosphothreonine1425 relationship: transforms_into CCO:B0012879 ! MDC1_HUMAN-Phosphoserine1430 relationship: transforms_into CCO:B0012880 ! MDC1_HUMAN-Phosphothreonine1461 relationship: transforms_into CCO:B0012881 ! MDC1_HUMAN-Phosphothreonine1623 relationship: transforms_into CCO:B0012882 ! MDC1_HUMAN-Phosphoserine1797 relationship: transforms_into CCO:B0012883 ! MDC1_HUMAN-Phosphoserine1814 relationship: transforms_into CCO:B0012884 ! MDC1_HUMAN-Phosphoserine1820 relationship: transforms_into CCO:B0048318 ! MDC1_HUMAN-Phosphoserine1399 relationship: transforms_into CCO:B0048319 ! MDC1_HUMAN-Phosphothreonine1403 relationship: transforms_into CCO:B0068078 ! MDC1_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0068079 ! MDC1_HUMAN-Phosphoserine299 relationship: transforms_into CCO:B0068080 ! MDC1_HUMAN-Phosphothreonine301 relationship: transforms_into CCO:B0068081 ! MDC1_HUMAN-Phosphothreonine341 relationship: transforms_into CCO:B0068082 ! MDC1_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0068083 ! MDC1_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0068084 ! MDC1_HUMAN-Phosphothreonine449 relationship: transforms_into CCO:B0068085 ! MDC1_HUMAN-Phosphoserine504 relationship: transforms_into CCO:B0068086 ! MDC1_HUMAN-Phosphoserine793 relationship: transforms_into CCO:B0068087 ! MDC1_HUMAN-Phosphoserine1033 relationship: transforms_into CCO:B0068088 ! MDC1_HUMAN-Phosphothreonine1198 relationship: transforms_into CCO:B0068089 ! MDC1_HUMAN-Phosphoserine1212 relationship: transforms_into CCO:B0068090 ! MDC1_HUMAN-Phosphoserine1400 relationship: transforms_into CCO:B0068091 ! MDC1_HUMAN-Phosphothreonine1444 relationship: transforms_into CCO:B0068092 ! MDC1_HUMAN-Phosphothreonine1466 relationship: transforms_into CCO:B0068093 ! MDC1_HUMAN-Phosphothreonine1589 relationship: transforms_into CCO:B0068094 ! MDC1_HUMAN-Phosphothreonine1601 relationship: transforms_into CCO:B0068095 ! MDC1_HUMAN-Phosphoserine1604 relationship: transforms_into CCO:B0068096 ! MDC1_HUMAN-Phosphothreonine1608 relationship: transforms_into CCO:B0068097 ! MDC1_HUMAN-Phosphothreonine1630 relationship: transforms_into CCO:B0068098 ! MDC1_HUMAN-Phosphothreonine1649 relationship: transforms_into CCO:B0068099 ! MDC1_HUMAN-Phosphothreonine1664 relationship: transforms_into CCO:B0068100 ! MDC1_HUMAN-Phosphothreonine1671 relationship: transforms_into CCO:B0068101 ! MDC1_HUMAN-Phosphoserine1681 relationship: transforms_into CCO:B0068102 ! MDC1_HUMAN-Phosphothreonine1696 relationship: transforms_into CCO:B0068103 ! MDC1_HUMAN-Phosphothreonine1697 relationship: transforms_into CCO:B0068104 ! MDC1_HUMAN-Phosphoserine1702 relationship: transforms_into CCO:B0068105 ! MDC1_HUMAN-Phosphoserine1711 relationship: transforms_into CCO:B0068106 ! MDC1_HUMAN-Phosphoserine1775 relationship: transforms_into CCO:B0068107 ! MDC1_HUMAN-Phosphothreonine1858 [Term] id: CCO:B0001789 name: KANK1_HUMAN def: "KN motif and ankyrin repeat domain-containing protein 1" [UniProtKB:Q14678] synonym: "Ankyrin repeat domain-containing protein 15" EXACT [UniProtKB:Q14678] synonym: "Kidney ankyrin repeat-containing protein" EXACT [UniProtKB:Q14678] xref: EMBL:AAH37495.1 xref: EMBL:BAA11489.2 xref: EMBL:CAH70388.1 xref: UniProtKB:Q14678 xref: UniProtKB:Q5W0W0 xref: UniProtKB:Q8IY65 xref: UniProtKB:Q8WX74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010894 ! KANK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001790 name: SMC1A_HUMAN def: "Structural maintenance of chromosomes protein 1A" [UniProtKB:Q14683] synonym: "Sb1.8" EXACT [UniProtKB:Q14683] synonym: "SMC1alpha protein" EXACT [UniProtKB:Q14683] xref: EMBL:AAB34405.1 xref: EMBL:AAI12128.1 xref: EMBL:BAA11495.2 xref: EMBL:CAI42089.1 xref: EMBL:CAI42646.1 xref: UniProtKB:O14995 xref: UniProtKB:Q14683 xref: UniProtKB:Q16351 xref: UniProtKB:Q2M228 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005625 ! SMC1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005964 ! smc1-mcm7-1 physical interaction relationship: participates_in CCO:I0005965 ! smc1-mcm7-3 physical interaction relationship: participates_in CCO:I0005966 ! mcm7-smc1-2 physical interaction relationship: participates_in CCO:I0005967 ! mcm6-smc1-1 physical interaction relationship: participates_in CCO:I0006227 ! smc1-mcm7-2 physical interaction relationship: participates_in CCO:I0006783 ! rad21-stag2 physical interaction relationship: participates_in CCO:I0006960 ! mdc1-atm-1 physical interaction relationship: participates_in CCO:I0007012 ! smc1-mcm7-4 direct interaction relationship: participates_in CCO:I0007013 ! smc1-mcm7-5 direct interaction relationship: participates_in CCO:I0007306 ! smc1-mcm7-6 physical interaction relationship: participates_in CCO:I0007307 ! smc1-rfc1-1 physical interaction relationship: participates_in CCO:I0007308 ! smc1-dpola-1 physical interaction relationship: participates_in CCO:I0007711 ! wapl-cspg6-4 physical interaction relationship: participates_in CCO:I0007712 ! wapl-cspg6-5 physical interaction relationship: participates_in CCO:I0007713 ! wapl-cspg6-6 physical interaction relationship: participates_in CCO:I0007714 ! wapl-cspg6-7 physical interaction relationship: participates_in CCO:I0007715 ! wapl-cspg6-9 physical interaction relationship: participates_in CCO:I0007821 ! mcm7-smc1-1 direct interaction relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: participates_in CCO:P0000078 ! mitotic sister chromatid cohesion relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0002125 ! DNA damage response, signal transduction relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014068 ! SMC1A_HUMAN-Phosphoserine358 relationship: transforms_into CCO:B0014069 ! SMC1A_HUMAN-Phosphoserine360 relationship: transforms_into CCO:B0014070 ! SMC1A_HUMAN-Phosphoserine951 relationship: transforms_into CCO:B0014071 ! SMC1A_HUMAN-Phosphoserine957 relationship: transforms_into CCO:B0014072 ! SMC1A_HUMAN-Phosphoserine962 relationship: transforms_into CCO:B0014073 ! SMC1A_HUMAN-Phosphoserine966 relationship: transforms_into CCO:B0070617 ! SMC1A_HUMAN-Phosphoserine970 [Term] id: CCO:B0001791 name: LTBP2_HUMAN def: "Latent-transforming growth factor beta-binding protein 2 precursor" [UniProtKB:Q14767] synonym: "LTBP-2" EXACT [UniProtKB:Q14767] xref: EMBL:AAB37459.1 xref: EMBL:AAF87081.1 xref: EMBL:CAA86030.1 xref: UniProtKB:Q14767 xref: UniProtKB:Q99907 xref: UniProtKB:Q9NS51 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004996 ! LTBP2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0001792 name: KIF22_HUMAN def: "Kinesin-like protein KIF22" [UniProtKB:Q14807] synonym: "Kinesin-like DNA-binding protein" EXACT [UniProtKB:Q14807] synonym: "Kinesin-like protein 4" EXACT [UniProtKB:Q14807] xref: EMBL:AAC08709.1 xref: EMBL:AAH04352.1 xref: EMBL:AAH28155.1 xref: EMBL:AAP35923.1 xref: EMBL:BAA33019.2 xref: EMBL:BAA33063.1 xref: EMBL:BAD97151.1 xref: EMBL:BAG35167.1 xref: EMBL:EAW80007.1 xref: UniProtKB:B2R5M0 xref: UniProtKB:O60845 xref: UniProtKB:O94814 xref: UniProtKB:Q14807 xref: UniProtKB:Q53F58 xref: UniProtKB:Q9BT46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004943 ! KIF22_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0008255 ! kif22-gdf9 physical interaction relationship: participates_in CCO:I0008256 ! kif22-immt physical interaction relationship: participates_in CCO:I0008257 ! kif22-pja1 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0012586 ! KIF22_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0012587 ! KIF22_HUMAN-Phosphoserine543 relationship: transforms_into CCO:B0012588 ! KIF22_HUMAN-Phosphoserine562 relationship: transforms_into CCO:B0012589 ! KIF22_HUMAN-Phosphoserine581 relationship: transforms_into CCO:B0067359 ! KIF22_HUMAN-Phosphoserine412 relationship: transforms_into CCO:B0067360 ! KIF22_HUMAN-Phosphoserine427 [Term] id: CCO:B0001793 name: NOLC1_HUMAN def: "Nucleolar phosphoprotein p130" [UniProtKB:Q14978] synonym: "140 kDa nucleolar phosphoprotein" EXACT [UniProtKB:Q14978] synonym: "HCV NS5A trans-regulated protein 13" EXACT [UniProtKB:Q14978] synonym: "Nopp140" EXACT [UniProtKB:Q14978] synonym: "NS5ATP13" EXACT [UniProtKB:Q14978] synonym: "Nucleolar 130 kDa protein" EXACT [UniProtKB:Q14978] synonym: "Nucleolar and coiled-body phosphoprotein 1" EXACT [UniProtKB:Q14978] xref: EMBL:AAH01883.1 xref: EMBL:AAV67777.1 xref: EMBL:BAA04803.1 xref: EMBL:CAA84063.1 xref: EMBL:CAH72220.1 xref: EMBL:EAW49714.1 xref: EMBL:EAW49715.1 xref: UniProtKB:Q14978 xref: UniProtKB:Q15030 xref: UniProtKB:Q5VV70 xref: UniProtKB:Q9BUV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005206 ! NOLC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0013221 ! NOLC1_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0013222 ! NOLC1_HUMAN-Phosphoserine84 relationship: transforms_into CCO:B0013223 ! NOLC1_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0013224 ! NOLC1_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0013225 ! NOLC1_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0013226 ! NOLC1_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0013227 ! NOLC1_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0013228 ! NOLC1_HUMAN-Phosphoserine508 relationship: transforms_into CCO:B0013229 ! NOLC1_HUMAN-Phosphoserine538 relationship: transforms_into CCO:B0013230 ! NOLC1_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0013231 ! NOLC1_HUMAN-Phosphothreonine607 relationship: transforms_into CCO:B0013232 ! NOLC1_HUMAN-Phosphothreonine610 relationship: transforms_into CCO:B0013233 ! NOLC1_HUMAN-Phosphoserine623 relationship: transforms_into CCO:B0013234 ! NOLC1_HUMAN-Phosphoserine643 relationship: transforms_into CCO:B0013235 ! NOLC1_HUMAN-Phosphoserine698 relationship: transforms_into CCO:B0068786 ! NOLC1_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0068787 ! NOLC1_HUMAN-Phosphoserine580 relationship: transforms_into CCO:B0068788 ! NOLC1_HUMAN-Phosphoserine582 relationship: transforms_into CCO:B0068789 ! NOLC1_HUMAN-Phosphoserine622 relationship: transforms_into CCO:B0068790 ! NOLC1_HUMAN-Phosphoserine686 [Term] id: CCO:B0001794 name: NUMA1_HUMAN def: "Nuclear mitotic apparatus protein 1" [UniProtKB:Q14980] synonym: "NuMA protein" EXACT [UniProtKB:Q14980] synonym: "SP-H antigen" EXACT [UniProtKB:Q14980] xref: EMBL:CAA77669.1 xref: EMBL:CAA77670.1 xref: UniProtKB:Q14980 xref: UniProtKB:Q14981 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005225 ! NUMA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006311 ! numa1-gpsm2-1 physical interaction relationship: participates_in CCO:I0006312 ! numa1-gnai1-1 physical interaction relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:I0006966 ! gnai1-numa1-1 physical interaction relationship: participates_in CCO:I0006967 ! gnai1-gpsm2-3 physical interaction relationship: participates_in CCO:I0006968 ! gpsm2-numa1-1 physical interaction relationship: participates_in CCO:I0007255 ! gpsm2-numa1-3 physical interaction relationship: participates_in CCO:I0007421 ! gpsm2-numa1-2 physical interaction relationship: participates_in CCO:I0007747 ! gnai1-gpsm2-2 physical interaction relationship: participates_in CCO:I0007750 ! gpsm2-numa1-4 physical interaction relationship: participates_in CCO:P0000020 ! mitotic anaphase relationship: participates_in CCO:P0000316 ! meiotic cell cycle relationship: transforms_into CCO:B0013293 ! NUMA1_HUMAN-Phosphoserine169 relationship: transforms_into CCO:B0013294 ! NUMA1_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0013295 ! NUMA1_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0013296 ! NUMA1_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0013297 ! NUMA1_HUMAN-Phosphothreonine211 relationship: transforms_into CCO:B0013298 ! NUMA1_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0013299 ! NUMA1_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0013300 ! NUMA1_HUMAN-Phosphoserine820 relationship: transforms_into CCO:B0013301 ! NUMA1_HUMAN-Phosphothreonine963 relationship: transforms_into CCO:B0013302 ! NUMA1_HUMAN-Phosphoserine1262 relationship: transforms_into CCO:B0013303 ! NUMA1_HUMAN-Phosphoserine1601 relationship: transforms_into CCO:B0013304 ! NUMA1_HUMAN-Phosphoserine1721 relationship: transforms_into CCO:B0013305 ! NUMA1_HUMAN-Phosphoserine1724 relationship: transforms_into CCO:B0013306 ! NUMA1_HUMAN-Phosphoserine1728 relationship: transforms_into CCO:B0013307 ! NUMA1_HUMAN-Phosphothreonine1733 relationship: transforms_into CCO:B0013308 ! NUMA1_HUMAN-Phosphoserine1757 relationship: transforms_into CCO:B0013309 ! NUMA1_HUMAN-Phosphoserine1760 relationship: transforms_into CCO:B0013310 ! NUMA1_HUMAN-Phosphoserine1769 relationship: transforms_into CCO:B0013311 ! NUMA1_HUMAN-Phosphoserine1772 relationship: transforms_into CCO:B0013312 ! NUMA1_HUMAN-Phosphotyrosine1774 relationship: transforms_into CCO:B0013313 ! NUMA1_HUMAN-Phosphothreonine1776 relationship: transforms_into CCO:B0013314 ! NUMA1_HUMAN-Phosphoserine1830 relationship: transforms_into CCO:B0013315 ! NUMA1_HUMAN-Phosphoserine1833 relationship: transforms_into CCO:B0013316 ! NUMA1_HUMAN-Phosphoserine1834 relationship: transforms_into CCO:B0013317 ! NUMA1_HUMAN-Phosphoserine1840 relationship: transforms_into CCO:B0013318 ! NUMA1_HUMAN-Phosphoserine1847 relationship: transforms_into CCO:B0013319 ! NUMA1_HUMAN-Phosphoserine1853 relationship: transforms_into CCO:B0013320 ! NUMA1_HUMAN-Phosphoserine1862 relationship: transforms_into CCO:B0013321 ! NUMA1_HUMAN-Phosphoserine1872 relationship: transforms_into CCO:B0013322 ! NUMA1_HUMAN-Phosphoserine1945 relationship: transforms_into CCO:B0013323 ! NUMA1_HUMAN-Phosphothreonine2000 relationship: transforms_into CCO:B0013324 ! NUMA1_HUMAN-Phosphothreonine2055 relationship: transforms_into CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: transforms_into CCO:B0013326 ! NUMA1_HUMAN-Phosphothreonine2106 relationship: transforms_into CCO:B0048341 ! NUMA1_HUMAN-Phosphoserine1969 relationship: transforms_into CCO:B0068917 ! NUMA1_HUMAN-Phosphoserine198 relationship: transforms_into CCO:B0068918 ! NUMA1_HUMAN-Phosphoserine1788 relationship: transforms_into CCO:B0068919 ! NUMA1_HUMAN-Phosphoserine1789 relationship: transforms_into CCO:B0068920 ! NUMA1_HUMAN-Phosphoserine1792 relationship: transforms_into CCO:B0068921 ! NUMA1_HUMAN-Phosphoserine1800 relationship: transforms_into CCO:B0068922 ! NUMA1_HUMAN-Phosphothreonine1804 relationship: transforms_into CCO:B0068923 ! NUMA1_HUMAN-Phosphotyrosine1836 relationship: transforms_into CCO:B0068924 ! NUMA1_HUMAN-Phosphoserine1837 relationship: transforms_into CCO:B0068925 ! NUMA1_HUMAN-Phosphoserine1887 relationship: transforms_into CCO:B0068926 ! NUMA1_HUMAN-Phosphoserine1991 [Term] id: CCO:B0001795 name: CUL7_HUMAN def: "Cullin-7" [UniProtKB:Q14999] synonym: "CUL-7" EXACT [UniProtKB:Q14999] xref: EMBL:AAH33647.1 xref: EMBL:BAA07551.2 xref: EMBL:CAI13779.1 xref: EMBL:CAI19793.1 xref: UniProtKB:Q14999 xref: UniProtKB:Q5T654 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004427 ! CUL7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006474 ! kiaa1206-cul7 physical interaction relationship: transforms_into CCO:B0065913 ! CUL7_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0065914 ! CUL7_HUMAN-Phosphoserine339 [Term] id: CCO:B0001796 name: HECAM_HUMAN def: "Hepatocyte cell adhesion molecule precursor" [UniProtKB:Q14CZ8] synonym: "Protein hepaCAM" EXACT [UniProtKB:Q14CZ8] xref: EMBL:AAI04832.1 xref: EMBL:AAI13563.1 xref: EMBL:AAQ93018.1 xref: EMBL:BAC05297.1 xref: EMBL:BAC85486.1 xref: EMBL:CAD39081.1 xref: UniProtKB:Q14CZ8 xref: UniProtKB:Q67IP8 xref: UniProtKB:Q6ZWL4 xref: UniProtKB:Q8N7I3 xref: UniProtKB:Q8ND35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004796 ! HEPACAM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0012177 ! HECAM_HUMAN-Phosphoserine278 relationship: transforms_into CCO:B0012178 ! HECAM_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0012179 ! HECAM_HUMAN-Phosphoserine350 [Term] id: CCO:B0001797 name: CND2_HUMAN def: "Condensin complex subunit 2" [UniProtKB:Q15003] synonym: "Barren homolog protein 1" EXACT [UniProtKB:Q15003] synonym: "Chromosome-associated protein H" EXACT [UniProtKB:Q15003] synonym: "hCAP-H" EXACT [UniProtKB:Q15003] synonym: "Non-SMC condensin I complex subunit H" EXACT [UniProtKB:Q15003] synonym: "XCAP-H homolog" EXACT [UniProtKB:Q15003] xref: EMBL:AAH24211.1 xref: EMBL:BAA07556.1 xref: UniProtKB:Q15003 xref: UniProtKB:Q8TB87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004377 ! NCAPH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000038 ! mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011296 ! CND2_HUMAN-Phosphothreonine49 relationship: transforms_into CCO:B0011297 ! CND2_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0011298 ! CND2_HUMAN-Phosphoserine81 relationship: transforms_into CCO:B0011299 ! CND2_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0011300 ! CND2_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0011301 ! CND2_HUMAN-Phosphoserine201 relationship: transforms_into CCO:B0011302 ! CND2_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0011303 ! CND2_HUMAN-Phosphothreonine605 relationship: transforms_into CCO:B0064409 ! CND2_HUMAN-Phosphoserine70 relationship: transforms_into CCO:B0064410 ! CND2_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0064411 ! CND2_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0064412 ! CND2_HUMAN-Phosphothreonine614 [Term] id: CCO:B0001798 name: FL2D_HUMAN def: "Pre-mRNA-splicing regulator WTAP" [UniProtKB:Q15007] synonym: "Female-lethal(2)D homolog" EXACT [UniProtKB:Q15007] synonym: "hFL(2)D" EXACT [UniProtKB:Q15007] synonym: "Wilms tumor 1-associating protein" EXACT [UniProtKB:Q15007] synonym: "WT1-associated protein" EXACT [UniProtKB:Q15007] xref: EMBL:AAH00383.1 xref: EMBL:AAH04432.1 xref: EMBL:AAH69192.1 xref: EMBL:AAK54764.1 xref: EMBL:BAA03495.1 xref: EMBL:CAC10188.1 xref: EMBL:CAC29495.1 xref: EMBL:CAI21849.1 xref: EMBL:EAW47622.1 xref: UniProtKB:Q15007 xref: UniProtKB:Q5TCL8 xref: UniProtKB:Q96T28 xref: UniProtKB:Q9BYJ7 xref: UniProtKB:Q9H4E2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004649 ! WTAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005921 ! magea11-wtap physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011883 ! FL2D_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0011884 ! FL2D_HUMAN-Phosphoserine306 [Term] id: CCO:B0001799 name: MD2BP_HUMAN def: "MAD2L1-binding protein" [UniProtKB:Q15013] synonym: "Caught by MAD2 protein" EXACT [UniProtKB:Q15013] xref: EMBL:AAH02904.1 xref: EMBL:BAA03552.1 xref: EMBL:CAC19507.1 xref: UniProtKB:Q15013 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005047 ! MAD2L1BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005937 ! krt15-mad2l1bp physical interaction relationship: participates_in CCO:I0008021 ! mad2l1bp-tp53 physical interaction relationship: participates_in CCO:I0008130 ! mad2l1bp-eef1a1 physical interaction relationship: participates_in CCO:I0008131 ! mad2l1bp-htatip physical interaction relationship: participates_in CCO:I0008132 ! mad2l1bp-ptn physical interaction relationship: participates_in CCO:I0008133 ! mad2l1bp-setdb1 physical interaction relationship: participates_in CCO:I0008260 ! mad2l1bp-kiaa1377 physical interaction relationship: participates_in CCO:I0008261 ! mad2l1bp-igsf21 physical interaction relationship: participates_in CCO:I0008262 ! mad2l1bp-rif1 physical interaction relationship: participates_in CCO:I0008405 ! mad2l1bp-trip13-1 physical interaction relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: transforms_into CCO:B0012846 ! MD2BP_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0012847 ! MD2BP_HUMAN-Phosphothreonine39 [Term] id: CCO:B0001800 name: SEPT2_HUMAN def: "Septin-2" [UniProtKB:Q15019] synonym: "NEDD-5" EXACT [UniProtKB:Q15019] synonym: "Neural precursor cell expressed developmentally down-regulated protein 5" EXACT [UniProtKB:Q15019] xref: EMBL:AAB92377.1 xref: EMBL:AAH14455.1 xref: EMBL:AAH33559.1 xref: EMBL:BAA05893.1 xref: EMBL:BAA09928.2 xref: UniProtKB:Q14132 xref: UniProtKB:Q15019 xref: UniProtKB:Q8IUK9 xref: UniProtKB:Q96CB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005585 ! SEPT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005732 ! dazap2-sept2 physical interaction relationship: participates_in CCO:I0005825 ! sept2-sept6 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013991 ! SEPT2_HUMAN-Phosphotyrosine17 relationship: transforms_into CCO:B0013992 ! SEPT2_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0013993 ! SEPT2_HUMAN-Phosphothreonine228 relationship: transforms_into CCO:B0070372 ! SEPT2_HUMAN-Phosphotyrosine211 [Term] id: CCO:B0001801 name: CND1_HUMAN def: "Condensin complex subunit 1" [UniProtKB:Q15021] synonym: "Chromosome condensation-related SMC-associated protein 1" EXACT [UniProtKB:Q15021] synonym: "Chromosome-associated protein D2" EXACT [UniProtKB:Q15021] synonym: "hCAP-D2" EXACT [UniProtKB:Q15021] synonym: "Non-SMC condensin I complex subunit D2" EXACT [UniProtKB:Q15021] synonym: "XCAP-D2 homolog" EXACT [UniProtKB:Q15021] xref: EMBL:AAH28182.1 xref: EMBL:BAA09930.2 xref: UniProtKB:Q15021 xref: UniProtKB:Q8N6U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004376 ! NCAPD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011280 ! CND1_HUMAN-Phosphothreonine103 relationship: transforms_into CCO:B0011281 ! CND1_HUMAN-Phosphothreonine577 relationship: transforms_into CCO:B0011282 ! CND1_HUMAN-Phosphoserine585 relationship: transforms_into CCO:B0011283 ! CND1_HUMAN-Phosphoserine1310 relationship: transforms_into CCO:B0011284 ! CND1_HUMAN-Phosphoserine1330 relationship: transforms_into CCO:B0011285 ! CND1_HUMAN-Phosphothreonine1331 relationship: transforms_into CCO:B0011286 ! CND1_HUMAN-Phosphoserine1333 relationship: transforms_into CCO:B0011287 ! CND1_HUMAN-Phosphothreonine1339 relationship: transforms_into CCO:B0011288 ! CND1_HUMAN-Phosphoserine1366 relationship: transforms_into CCO:B0011289 ! CND1_HUMAN-Phosphoserine1367 relationship: transforms_into CCO:B0011290 ! CND1_HUMAN-Phosphoserine1370 relationship: transforms_into CCO:B0011291 ! CND1_HUMAN-Phosphoserine1371 relationship: transforms_into CCO:B0011292 ! CND1_HUMAN-Phosphoserine1376 relationship: transforms_into CCO:B0011293 ! CND1_HUMAN-Phosphothreonine1384 relationship: transforms_into CCO:B0011294 ! CND1_HUMAN-Phosphothreonine1388 relationship: transforms_into CCO:B0011295 ! CND1_HUMAN-Phosphothreonine1389 relationship: transforms_into CCO:B0048204 ! CND1_HUMAN-Phosphothreonine586 [Term] id: CCO:B0001802 name: CD5R1_HUMAN def: "Cyclin-dependent kinase 5 activator 1 precursor" [UniProtKB:Q15078] synonym: "CDK5 activator 1" EXACT [UniProtKB:Q15078] synonym: "Cyclin-dependent kinase 5 regulatory subunit 1" EXACT [UniProtKB:Q15078] synonym: "p23" EXACT [UniProtKB:Q15078] synonym: "Tau protein kinase II 23 kDa subunit" EXACT [UniProtKB:Q15078] synonym: "TPKII regulatory subunit" EXACT [UniProtKB:Q15078] xref: EMBL:AAH20580.1 xref: EMBL:AAQ74776.1 xref: EMBL:CAA56587.1 xref: UniProtKB:Q15078 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004280 ! CDK5R1_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003202 ! cyclin-dependent protein kinase 5 activator activity relationship: has_function CCO:F0005870 ! protein serine/threonine kinase activator activity relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000803 ! cyclin-dependent protein kinase 5 activator complex relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001300 ! neuromuscular junction relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0001729 ! dendritic spine relationship: located_in CCO:C0001766 ! contractile fiber relationship: participates_in CCO:I0005786 ! cdk5r1-tsc22d4 physical interaction relationship: participates_in CCO:I0007828 ! cdk5-cdk5r1-1 direct interaction relationship: participates_in CCO:I0007829 ! cdk5-cdk5r1-2 direct interaction relationship: participates_in CCO:I0007830 ! cdk5-cdk5r1-3 direct interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002011 ! ionotropic glutamate receptor signaling pathway relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation [Term] id: CCO:B0001803 name: CDK10_HUMAN def: "Cell division protein kinase 10" [UniProtKB:Q15131] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q15131] synonym: "Serine/threonine-protein kinase PISSLRE" EXACT [UniProtKB:Q15131] xref: EMBL:AAA60092.2 xref: EMBL:AAH17342.1 xref: EMBL:AAH25301.1 xref: EMBL:CAA55137.1 xref: EMBL:CAB37619.1 xref: EMBL:CAL37781.1 xref: EMBL:CAL38055.1 xref: EMBL:CAL38082.1 xref: UniProtKB:Q0VGZ7 xref: UniProtKB:Q15130 xref: UniProtKB:Q15131 xref: UniProtKB:Q6PJC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004298 ! CDK10_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000100 ! traversing start control point of mitotic cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0011102 ! CDK10_HUMAN-Phosphothreonine196 [Term] id: CCO:B0001804 name: E2F5_HUMAN def: "Transcription factor E2F5" [UniProtKB:Q15329] synonym: "E2F-5" EXACT [UniProtKB:Q15329] xref: EMBL:AAB00179.1 xref: EMBL:AAC50120.1 xref: EMBL:AAN46737.1 xref: EMBL:CAA60051.1 xref: EMBL:CAB01634.1 xref: UniProtKB:Q15329 xref: UniProtKB:Q16601 xref: UniProtKB:Q92756 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004537 ! E2F5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001805 name: Q15354_HUMAN def: "Orf 2 protein" [UniProtKB:Q15354] synonym: "Platelet-derived growth factor beta polypeptide (Simian sarcoma viral (V-sis) oncogene homolog)" EXACT [UniProtKB:Q15354] xref: EMBL:CAA58679.1 xref: EMBL:CAP58849.1 xref: UniProtKB:Q15354 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005989 ! orf 2_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001806 name: DHC24_HUMAN def: "24-dehydrocholesterol reductase precursor" [UniProtKB:Q15392] synonym: "3-beta-hydroxysterol delta-24-reductase" EXACT [UniProtKB:Q15392] synonym: "Diminuto/dwarf1 homolog" EXACT [UniProtKB:Q15392] synonym: "EC 1.3.1.-" EXACT [UniProtKB:Q15392] synonym: "Seladin-1" EXACT [UniProtKB:Q15392] xref: EMBL:AAG17288.1 xref: EMBL:AAH04375.1 xref: EMBL:AAH11669.1 xref: EMBL:AAL15644.1 xref: EMBL:BAA02806.3 xref: UniProtKB:Q15392 xref: UniProtKB:Q9HBA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004466 ! DHCR24_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005688 ! peptide antigen binding relationship: has_function CCO:F0007948 ! delta24-sterol reductase activity relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: participates_in CCO:P0002235 ! neuroprotection relationship: transforms_into CCO:B0011501 ! DHC24_HUMAN-Phosphothreonine110 [Term] id: CCO:B0001807 name: DLGP5_HUMAN def: "Disks large-associated protein 5" [UniProtKB:Q15398] synonym: "DAP-5" EXACT [UniProtKB:Q15398] synonym: "Discs large homolog 7" EXACT [UniProtKB:Q15398] synonym: "Disks large-associated protein DLG7" EXACT [UniProtKB:Q15398] synonym: "Hepatoma up-regulated protein" EXACT [UniProtKB:Q15398] synonym: "HURP" EXACT [UniProtKB:Q15398] xref: EMBL:AAH10658.2 xref: EMBL:AAH16276.2 xref: EMBL:AAP36008.1 xref: EMBL:BAA02797.2 xref: EMBL:BAB97376.1 xref: UniProtKB:Q15398 xref: UniProtKB:Q8NG58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014344 ! DLGAP5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005828 ! dlg7-traf2 physical interaction relationship: participates_in CCO:I0005829 ! dlg7-trim37 physical interaction relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000093 ! mitotic chromosome movement towards spindle pole relationship: participates_in CCO:P0000253 ! positive regulation of mitotic metaphase/anaphase transition relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0048227 ! DLGP5_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0048228 ! DLGP5_HUMAN-Phosphothreonine219 relationship: transforms_into CCO:B0048229 ! DLGP5_HUMAN-Phosphothreonine224 relationship: transforms_into CCO:B0048230 ! DLGP5_HUMAN-Phosphothreonine329 relationship: transforms_into CCO:B0048231 ! DLGP5_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0048232 ! DLGP5_HUMAN-Phosphothreonine402 relationship: transforms_into CCO:B0048233 ! DLGP5_HUMAN-Phosphoserine618 relationship: transforms_into CCO:B0048234 ! DLGP5_HUMAN-Phosphothreonine639 relationship: transforms_into CCO:B0048235 ! DLGP5_HUMAN-Phosphoserine642 relationship: transforms_into CCO:B0048236 ! DLGP5_HUMAN-Phosphoserine662 relationship: transforms_into CCO:B0048237 ! DLGP5_HUMAN-Phosphoserine689 relationship: transforms_into CCO:B0048238 ! DLGP5_HUMAN-Phosphothreonine759 relationship: transforms_into CCO:B0048239 ! DLGP5_HUMAN-Phosphoserine774 relationship: transforms_into CCO:B0048240 ! DLGP5_HUMAN-Phosphoserine777 relationship: transforms_into CCO:B0048241 ! DLGP5_HUMAN-Phosphoserine806 relationship: transforms_into CCO:B0048242 ! DLGP5_HUMAN-Phosphoserine812 relationship: transforms_into CCO:B0048243 ! DLGP5_HUMAN-Phosphoserine830 relationship: transforms_into CCO:B0048244 ! DLGP5_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0064779 ! DLGP5_HUMAN-Phosphothreonine326 relationship: transforms_into CCO:B0064780 ! DLGP5_HUMAN-Phosphothreonine338 relationship: transforms_into CCO:B0064781 ! DLGP5_HUMAN-Phosphothreonine344 relationship: transforms_into CCO:B0064782 ! DLGP5_HUMAN-Phosphoserine725 relationship: transforms_into CCO:B0064783 ! DLGP5_HUMAN-Phosphothreonine784 relationship: transforms_into CCO:B0064784 ! DLGP5_HUMAN-Phosphothreonine799 [Term] id: CCO:B0001808 name: SYCP1_HUMAN def: "Synaptonemal complex protein 1" [UniProtKB:Q15431] synonym: "Cancer/testis antigen 8" EXACT [UniProtKB:Q15431] synonym: "CT8" EXACT [UniProtKB:Q15431] synonym: "SCP-1" EXACT [UniProtKB:Q15431] xref: EMBL:AAI26267.1 xref: EMBL:BAA22586.1 xref: EMBL:CAA64956.1 xref: EMBL:CAH70064.1 xref: EMBL:CAH72847.1 xref: EMBL:EAW56622.1 xref: UniProtKB:O14963 xref: UniProtKB:Q15431 xref: UniProtKB:Q5VXJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005710 ! SYCP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000121 ! synaptonemal complex assembly relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0071024 ! SYCP1_HUMAN-Phosphotyrosine257 [Term] id: CCO:B0001809 name: SPHAR_HUMAN def: "Protein SPHAR" [UniProtKB:Q15513] synonym: "S-phase response protein" EXACT [UniProtKB:Q15513] xref: EMBL:AAZ15373.1 xref: EMBL:CAA57901.1 xref: EMBL:CAC17573.1 xref: UniProtKB:Q15513 xref: UniProtKB:Q4EW09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005659 ! SPHAR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0001810 name: TERF2_HUMAN def: "Telomeric repeat-binding factor 2" [UniProtKB:Q15554] synonym: "Telomeric DNA-binding protein" EXACT [UniProtKB:Q15554] synonym: "TTAGGG repeat-binding factor 2" EXACT [UniProtKB:Q15554] xref: EMBL:AAB81135.1 xref: EMBL:AAD00821.1 xref: EMBL:AAH24890.1 xref: EMBL:CAA63769.1 xref: UniProtKB:Q15554 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005761 ! TERF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006212 ! wrn-terf2-3 colocalization relationship: participates_in CCO:I0006327 ! pot1-terf2 physical interaction relationship: participates_in CCO:I0006328 ! acd-terf2 physical interaction relationship: participates_in CCO:I0006329 ! rap1-terf2-2 physical interaction relationship: participates_in CCO:I0006330 ! terf2-tinf2 physical interaction relationship: participates_in CCO:I0006331 ! rap1-terf2-3 physical interaction relationship: participates_in CCO:I0006534 ! wrn-terf2-1 physical interaction relationship: participates_in CCO:I0006538 ! blm-terf2-4 colocalization relationship: participates_in CCO:I0006875 ! wrn-terf2-4 direct interaction relationship: participates_in CCO:I0006876 ! wrn-terf2-5 direct interaction relationship: participates_in CCO:I0006877 ! wrn-terf2-6 direct interaction relationship: participates_in CCO:I0006878 ! wrn-terf2-7 direct interaction relationship: participates_in CCO:I0006881 ! blm-terf2-9 direct interaction relationship: participates_in CCO:I0006882 ! blm-terf2-10 direct interaction relationship: participates_in CCO:I0006981 ! wrn-terf2-2 physical interaction relationship: participates_in CCO:I0007131 ! terf2ip-rad50 physical interaction relationship: participates_in CCO:I0007283 ! blm-terf2-1 physical interaction relationship: participates_in CCO:I0007358 ! blm-terf2-2 physical interaction relationship: participates_in CCO:I0007359 ! blm-terf2-5 colocalization relationship: participates_in CCO:I0007573 ! wrn-terf2-8 direct interaction relationship: participates_in CCO:I0007574 ! blm-terf2-3 direct interaction relationship: participates_in CCO:I0007768 ! blm-terf2-6 direct interaction relationship: participates_in CCO:I0007893 ! pot1-terf2-1 physical interaction relationship: participates_in CCO:I0007894 ! tinf2-terf1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: participates_in CCO:P0001547 ! negative regulation of telomere maintenance relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014334 ! TERF2_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0014335 ! TERF2_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0014336 ! TERF2_HUMAN-Phosphoserine380 [Term] id: CCO:B0001811 name: MARE2_HUMAN def: "Microtubule-associated protein RP/EB family member 2" [UniProtKB:Q15555] synonym: "APC-binding protein EB2" EXACT [UniProtKB:Q15555] synonym: "EB2" EXACT [UniProtKB:Q15555] synonym: "End-binding protein 2" EXACT [UniProtKB:Q15555] xref: EMBL:AAH07318.1 xref: EMBL:AAV38889.1 xref: EMBL:BAA83375.1 xref: EMBL:CAA63923.1 xref: EMBL:CAG38782.1 xref: UniProtKB:Q15555 xref: UniProtKB:Q9UQ33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005025 ! MAPRE2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005722 ! lmo2-mapre2 physical interaction relationship: participates_in CCO:I0005846 ! mapre2-nif3l1 physical interaction relationship: participates_in CCO:I0005859 ! mapre2-mapre2 physical interaction relationship: participates_in CCO:I0005892 ! mapre2-mapre3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012767 ! MARE2_HUMAN-Phosphotyrosine167 relationship: transforms_into CCO:B0012768 ! MARE2_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0012769 ! MARE2_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0012770 ! MARE2_HUMAN-Phosphoserine223 relationship: transforms_into CCO:B0067988 ! MARE2_HUMAN-Phosphoserine208 [Term] id: CCO:B0001812 name: MARE1_HUMAN def: "Microtubule-associated protein RP/EB family member 1" [UniProtKB:Q15691] synonym: "APC-binding protein EB1" EXACT [UniProtKB:Q15691] synonym: "EB1" EXACT [UniProtKB:Q15691] synonym: "End-binding protein 1" EXACT [UniProtKB:Q15691] xref: EMBL:AAC09471.1 xref: EMBL:AAI06069.1 xref: EMBL:AAI09282.1 xref: EMBL:CAB53072.1 xref: UniProtKB:Q15691 xref: UniProtKB:Q3KQS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005024 ! MAPRE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005963 ! pin2_trf1-eb1-1 physical interaction relationship: participates_in CCO:I0007457 ! eb1-apc-1 physical interaction relationship: participates_in CCO:I0007458 ! eb1-pin2_trf1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001385 ! negative regulation of microtubule polymerization relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012763 ! MARE1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0012764 ! MARE1_HUMAN-Phosphotyrosine124 relationship: transforms_into CCO:B0012765 ! MARE1_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0012766 ! MARE1_HUMAN-Phosphothreonine166 [Term] id: CCO:B0001813 name: UB2V2_HUMAN def: "Ubiquitin-conjugating enzyme E2 variant 2" [UniProtKB:Q15819] synonym: "DDVit 1" EXACT [UniProtKB:Q15819] synonym: "EDPF-1" EXACT [UniProtKB:Q15819] synonym: "Enterocyte differentiation-associated factor EDAF-1" EXACT [UniProtKB:Q15819] synonym: "Enterocyte differentiation-promoting factor" EXACT [UniProtKB:Q15819] synonym: "MMS2" EXACT [UniProtKB:Q15819] synonym: "Vitamin D3-inducible protein" EXACT [UniProtKB:Q15819] xref: EMBL:AAB04758.2 xref: EMBL:AAC05381.1 xref: EMBL:AAH07051.1 xref: EMBL:AAH16332.1 xref: EMBL:AAH16710.1 xref: EMBL:AAH28673.1 xref: EMBL:AAH62418.1 xref: EMBL:AAP35390.1 xref: EMBL:CAA66717.1 xref: EMBL:CAG28556.1 xref: UniProtKB:Q15819 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005855 ! UBE2V2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001220 ! UBC13-MMS2 complex relationship: participates_in CCO:I0007165 ! ube2n-ube2v2-1 direct interaction relationship: participates_in CCO:I0008185 ! ube2v2-igsf21 physical interaction relationship: participates_in CCO:I0008299 ! prei3-ube2v2 physical interaction relationship: participates_in CCO:I0008349 ! ube2v2-rif1 physical interaction relationship: participates_in CCO:I0008510 ! suv39h2-ube2v2 physical interaction relationship: participates_in CCO:P0000643 ! regulation of DNA repair relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001814 name: STK11_HUMAN def: "Serine/threonine-protein kinase 11" [UniProtKB:Q15831] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q15831] synonym: "Renal carcinoma antigen NY-REN-19" EXACT [UniProtKB:Q15831] synonym: "Serine/threonine-protein kinase LKB1" EXACT [UniProtKB:Q15831] xref: EMBL:AAB05809.1 xref: EMBL:AAB97833.1 xref: EMBL:AAC15742.1 xref: EMBL:AAC39527.1 xref: EMBL:AAH07981.1 xref: EMBL:AAH19334.1 xref: UniProtKB:Q15831 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005691 ! STK11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006454 ! lkb1-strad-2 physical interaction relationship: participates_in CCO:I0006455 ! lkb1-strad-4 physical interaction relationship: participates_in CCO:I0006456 ! stk11-strad-5 physical interaction relationship: participates_in CCO:I0006778 ! lkb1-strad-7 phosphorylation relationship: participates_in CCO:I0006779 ! lkb1-strad-8 phosphorylation relationship: participates_in CCO:I0006927 ! stk11-strad-6 colocalization relationship: participates_in CCO:I0007201 ! stk11-mo25-1 physical interaction relationship: participates_in CCO:I0007208 ! als2cr2-stk11-1 physical interaction relationship: participates_in CCO:I0007217 ! stk11-mark4-1 physical interaction relationship: participates_in CCO:I0007222 ! mo25-stk11-1 physical interaction relationship: participates_in CCO:I0007223 ! stk11-als2cr2-1 physical interaction relationship: participates_in CCO:I0007474 ! lkb1-strad-1 physical interaction relationship: participates_in CCO:I0008491 ! prei3-stk11 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0014250 ! STK11_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0014251 ! STK11_HUMAN-Phosphothreonine336 relationship: transforms_into CCO:B0014252 ! STK11_HUMAN-Phosphothreonine363 relationship: transforms_into CCO:B0014253 ! STK11_HUMAN-Phosphoserine428 [Term] id: CCO:B0001815 name: Q16164_HUMAN def: "G1 phase-specific gene protein" [UniProtKB:Q16164] xref: EMBL:AAB30172.1 xref: UniProtKB:Q16164 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005990 ! G1 phase-specific gene_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle [Term] id: CCO:B0001816 name: SEPT7_HUMAN def: "Septin-7" [UniProtKB:Q16181] synonym: "CDC10 protein homolog" EXACT [UniProtKB:Q16181] xref: EMBL:AAB31337.1 xref: EMBL:AAH67264.2 xref: EMBL:AAH93640.2 xref: EMBL:AAH93642.2 xref: UniProtKB:Q16181 xref: UniProtKB:Q52M76 xref: UniProtKB:Q6NX50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005590 ! SEPT7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014003 ! SEPT7_HUMAN-Phosphothreonine228 relationship: transforms_into CCO:B0014004 ! SEPT7_HUMAN-Phosphotyrosine319 relationship: transforms_into CCO:B0014005 ! SEPT7_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0014006 ! SEPT7_HUMAN-Phosphoserine423 relationship: transforms_into CCO:B0014007 ! SEPT7_HUMAN-Phosphothreonine426 relationship: transforms_into CCO:B0031373 ! SEPT7_HUMAN-Phosphotyrosine30 relationship: transforms_into CCO:B0070373 ! SEPT7_HUMAN-Phosphoserine424 [Term] id: CCO:B0001817 name: E2F4_HUMAN def: "Transcription factor E2F4" [UniProtKB:Q16254] synonym: "E2F-4" EXACT [UniProtKB:Q16254] xref: EMBL:AAB32597.1 xref: EMBL:AAC50119.1 xref: EMBL:AAF65226.1 xref: EMBL:AAH33180.1 xref: EMBL:AAM77918.1 xref: EMBL:CAA60050.2 xref: EMBL:EAW83094.1 xref: UniProtKB:A6NGR8 xref: UniProtKB:Q12991 xref: UniProtKB:Q15328 xref: UniProtKB:Q16254 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004536 ! E2F4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0006018 ! e2f4-trrap-1 physical interaction relationship: participates_in CCO:P0000013 ! G1/S-specific transcription in mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0001818 name: EXT1_HUMAN def: "Exostosin-1" [UniProtKB:Q16394] synonym: "EC 2.4.1.224" EXACT [UniProtKB:Q16394] synonym: "EC 2.4.1.225" EXACT [UniProtKB:Q16394] synonym: "Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase" EXACT [UniProtKB:Q16394] synonym: "Multiple exostoses protein 1" EXACT [UniProtKB:Q16394] synonym: "Putative tumor suppressor protein EXT1" EXACT [UniProtKB:Q16394] xref: EMBL:AAB62283.1 xref: EMBL:AAC51154.1 xref: EMBL:AAH01174.1 xref: UniProtKB:Q16394 xref: UniProtKB:Q9BVI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004602 ! EXT1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001851 ! acetylglucosaminyltransferase activity relationship: has_function CCO:F0002526 ! glucuronosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0005661 ! heparan sulfate N-acetylglucosaminyltransferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007845 ! glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity relationship: has_function CCO:F0007846 ! N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0001819 name: CDC37_HUMAN def: "Hsp90 co-chaperone Cdc37" [UniProtKB:Q16543] synonym: "Hsp90 chaperone protein kinase-targeting subunit" EXACT [UniProtKB:Q16543] synonym: "p50Cdc37" EXACT [UniProtKB:Q16543] xref: EMBL:AAB04798.1 xref: EMBL:AAB63979.1 xref: EMBL:AAH00083.1 xref: EMBL:AAH08793.1 xref: EMBL:AAW34362.1 xref: UniProtKB:Q16543 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004289 ! CDC37_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005999 ! cdc37-cdk4 physical interaction relationship: participates_in CCO:I0006427 ! map3k14-cdc37 physical interaction relationship: participates_in CCO:I0006430 ! chuk-cdc37 physical interaction relationship: participates_in CCO:I0006431 ! ikbkb-cdc37 physical interaction relationship: participates_in CCO:I0006432 ! ikbke-cdc37 physical interaction relationship: participates_in CCO:I0006433 ! ikbkg-cdc37 physical interaction relationship: participates_in CCO:I0006434 ! map3k1-cdc37 physical interaction relationship: participates_in CCO:I0006436 ! map3k3-cdc37 physical interaction relationship: participates_in CCO:I0006439 ! tbk1-cdc37 physical interaction relationship: participates_in CCO:I0006608 ! cdk6-cdc37-1 physical interaction relationship: participates_in CCO:I0006609 ! cdk4-cdc37-1 physical interaction relationship: participates_in CCO:I0006872 ! eif2ak1-cdc37-8 physical interaction relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:I0007182 ! nuak2-cdc37-1 physical interaction relationship: participates_in CCO:I0007392 ! cdk4-cdc37 physical interaction relationship: participates_in CCO:I0007393 ! cdk6-cdc37 physical interaction relationship: participates_in CCO:I0007396 ! cdc37-hsp90 physical interaction relationship: participates_in CCO:I0007397 ! cdc37-akt1 physical interaction relationship: participates_in CCO:I0007398 ! cdc37-akt2 physical interaction relationship: participates_in CCO:I0007399 ! cdc37-akt3 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: transforms_into CCO:B0011082 ! CDC37_HUMAN-Phosphotyrosine298 relationship: transforms_into CCO:B0064191 ! CDC37_HUMAN-Phosphoserine377 [Term] id: CCO:B0001820 name: M3K11_HUMAN def: "Mitogen-activated protein kinase kinase kinase 11" [UniProtKB:Q16584] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q16584] synonym: "Mixed lineage kinase 3" EXACT [UniProtKB:Q16584] synonym: "Src-homology 3 domain-containing proline-rich kinase" EXACT [UniProtKB:Q16584] xref: EMBL:AAA19647.1 xref: EMBL:AAA59859.1 xref: EMBL:AAH11263.1 xref: EMBL:AAH64543.1 xref: EMBL:BAD92892.1 xref: EMBL:BAD96501.1 xref: UniProtKB:Q16584 xref: UniProtKB:Q53H00 xref: UniProtKB:Q59F06 xref: UniProtKB:Q6P2G4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005004 ! MAP3K11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006963 ! map4k2-mlk3-1 physical interaction relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002689 ! regulation of JNK cascade relationship: transforms_into CCO:B0012715 ! M3K11_HUMAN-Phosphothreonine277 relationship: transforms_into CCO:B0012716 ! M3K11_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0012717 ! M3K11_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0012718 ! M3K11_HUMAN-Phosphoserine524 relationship: transforms_into CCO:B0012719 ! M3K11_HUMAN-Phosphoserine555 relationship: transforms_into CCO:B0012720 ! M3K11_HUMAN-Phosphoserine556 relationship: transforms_into CCO:B0012721 ! M3K11_HUMAN-Phosphoserine654 relationship: transforms_into CCO:B0012722 ! M3K11_HUMAN-Phosphoserine705 relationship: transforms_into CCO:B0012723 ! M3K11_HUMAN-Phosphoserine724 relationship: transforms_into CCO:B0012724 ! M3K11_HUMAN-Phosphoserine727 relationship: transforms_into CCO:B0012725 ! M3K11_HUMAN-Phosphothreonine738 relationship: transforms_into CCO:B0012726 ! M3K11_HUMAN-Phosphoserine740 relationship: transforms_into CCO:B0012727 ! M3K11_HUMAN-Phosphoserine746 relationship: transforms_into CCO:B0012728 ! M3K11_HUMAN-Phosphoserine758 relationship: transforms_into CCO:B0012729 ! M3K11_HUMAN-Phosphoserine770 relationship: transforms_into CCO:B0012730 ! M3K11_HUMAN-Phosphoserine793 relationship: transforms_into CCO:B0067805 ! M3K11_HUMAN-Phosphoserine789 [Term] id: CCO:B0001821 name: CCNG2_HUMAN def: "Cyclin-G2" [UniProtKB:Q16589] xref: EMBL:AAC41978.1 xref: EMBL:AAC50689.1 xref: EMBL:AAN40704.1 xref: EMBL:AAV38310.1 xref: UniProtKB:Q16589 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004255 ! CCNG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0035990 ! CCNG2_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0035991 ! CCNG2_HUMAN-Phosphoserine234 [Term] id: CCO:B0001822 name: MK06_HUMAN def: "Mitogen-activated protein kinase 6" [UniProtKB:Q16659] synonym: "EC 2.7.11.24" EXACT [UniProtKB:Q16659] synonym: "ERK-3" EXACT [UniProtKB:Q16659] synonym: "Extracellular signal-regulated kinase 3" EXACT [UniProtKB:Q16659] synonym: "MAP kinase isoform p97" EXACT [UniProtKB:Q16659] synonym: "p97-MAPK" EXACT [UniProtKB:Q16659] xref: EMBL:AAA98769.1 xref: EMBL:AAH35492.1 xref: EMBL:AAL17605.1 xref: EMBL:CAA56709.1 xref: EMBL:CAH18246.1 xref: UniProtKB:Q16659 xref: UniProtKB:Q68DH4 xref: UniProtKB:Q8IYN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005092 ! MAPK6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012944 ! MK06_HUMAN-Phosphothreonine626 relationship: transforms_into CCO:B0012945 ! MK06_HUMAN-Phosphotyrosine628 relationship: transforms_into CCO:B0068207 ! MK06_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0068208 ! MK06_HUMAN-Phosphoserine386 relationship: transforms_into CCO:B0068209 ! MK06_HUMAN-Phosphothreonine389 relationship: transforms_into CCO:B0068210 ! MK06_HUMAN-Phosphoserine665 [Term] id: CCO:B0001823 name: CDKN3_HUMAN def: "Cyclin-dependent kinase inhibitor 3" [UniProtKB:Q16667] synonym: "CDK2-associated dual-specificity phosphatase" EXACT [UniProtKB:Q16667] synonym: "Cyclin-dependent kinase interactor 1" EXACT [UniProtKB:Q16667] synonym: "Cyclin-dependent kinase-interacting protein 2" EXACT [UniProtKB:Q16667] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q16667] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q16667] synonym: "Kinase-associated phosphatase" EXACT [UniProtKB:Q16667] xref: EMBL:AAA60222.1 xref: EMBL:AAA66496.1 xref: EMBL:AAC04932.1 xref: EMBL:AAK06365.1 xref: EMBL:AAK06368.1 xref: EMBL:AAK06370.1 xref: EMBL:AAK06371.1 xref: EMBL:AAK06373.1 xref: EMBL:AAK06374.1 xref: EMBL:AAK06377.1 xref: EMBL:AAK06378.1 xref: EMBL:AAK06384.1 xref: EMBL:AAN86348.1 xref: UniProtKB:Q16667 xref: UniProtKB:Q99585 xref: UniProtKB:Q9BPW7 xref: UniProtKB:Q9BY36 xref: UniProtKB:Q9C042 xref: UniProtKB:Q9C047 xref: UniProtKB:Q9C049 xref: UniProtKB:Q9C051 xref: UniProtKB:Q9C053 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004308 ! CDKN3_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006566 ! cdk2-cdkn3-1 direct interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0001824 name: DUS6_HUMAN def: "Dual specificity protein phosphatase 6" [UniProtKB:Q16828] synonym: "Dual specificity protein phosphatase PYST1" EXACT [UniProtKB:Q16828] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q16828] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q16828] synonym: "MAP kinase phosphatase 3" EXACT [UniProtKB:Q16828] synonym: "Mitogen-activated protein kinase phosphatase 3" EXACT [UniProtKB:Q16828] synonym: "MKP-3" EXACT [UniProtKB:Q16828] xref: EMBL:AAH03143.1 xref: EMBL:AAH03562.1 xref: EMBL:AAH05047.1 xref: EMBL:AAH37236.1 xref: EMBL:AAP35541.1 xref: EMBL:BAA31968.1 xref: EMBL:BAA31969.1 xref: EMBL:BAA34369.1 xref: EMBL:CAA63813.1 xref: UniProtKB:O75109 xref: UniProtKB:Q16828 xref: UniProtKB:Q53Y75 xref: UniProtKB:Q9BSH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004523 ! DUSP6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005797 ! dusp6-mdfi physical interaction relationship: participates_in CCO:I0005868 ! dusp6-tex11 physical interaction relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: transforms_into CCO:B0064906 ! DUS6_HUMAN-Phosphoserine331 [Term] id: CCO:B0001825 name: TPD53_HUMAN def: "Tumor protein D53" [UniProtKB:Q16890] synonym: "hD53" EXACT [UniProtKB:Q16890] synonym: "Tumor protein D52-like 1" EXACT [UniProtKB:Q16890] xref: EMBL:AAB40894.1 xref: EMBL:AAB40895.1 xref: UniProtKB:Q16890 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005817 ! TPD52L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006044 ! hd52-hd53-1 physical interaction relationship: participates_in CCO:I0006045 ! hd53-hd52-1 physical interaction relationship: participates_in CCO:I0006046 ! hd53-hd53-1 physical interaction relationship: participates_in CCO:I0006739 ! hd53-hd53-2 physical interaction relationship: participates_in CCO:I0006740 ! hd53-hd53-3 physical interaction relationship: participates_in CCO:I0006741 ! hd53-hd53-4 physical interaction relationship: participates_in CCO:I0007413 ! nyd_sp25-tpd53 physical interaction relationship: participates_in CCO:I0007586 ! hd52-hd53-2 physical interaction relationship: participates_in CCO:I0008344 ! tpd52l1-c7orf36 physical interaction relationship: participates_in CCO:I0008345 ! tpd52l1-eif3s1 physical interaction relationship: participates_in CCO:I0008443 ! tpd52l1-gpr135 physical interaction relationship: participates_in CCO:I0008444 ! tpd52l1-hdac1 physical interaction relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: transforms_into CCO:B0071476 ! TPD53_HUMAN-Phosphoserine149 [Term] id: CCO:B0001827 name: Q1WWK5_HUMAN def: "SEPT9 protein" [UniProtKB:Q1WWK5] xref: EMBL:AAI14551.1 xref: UniProtKB:Q1WWK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005592 ! SEPT9_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001829 name: PDS5A_HUMAN def: "Sister chromatid cohesion protein PDS5 homolog A" [UniProtKB:Q29RF7] synonym: "Cell proliferation-inducing gene 54 protein" EXACT [UniProtKB:Q29RF7] synonym: "SCC-112" EXACT [UniProtKB:Q29RF7] synonym: "Sister chromatid cohesion protein 112" EXACT [UniProtKB:Q29RF7] xref: EMBL:AAH41361.1 xref: EMBL:AAI14219.1 xref: EMBL:AAI26226.1 xref: EMBL:AAM82347.1 xref: EMBL:AAT52214.1 xref: EMBL:BAA31623.1 xref: EMBL:BAC05286.1 xref: EMBL:CAH18263.1 xref: UniProtKB:Q29RF7 xref: UniProtKB:Q2TTR5 xref: UniProtKB:Q68DF7 xref: UniProtKB:Q8N7J4 xref: UniProtKB:Q8NG14 xref: UniProtKB:Q9Y4D4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005295 ! PDS5A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007039 ! wapl-cspg6-1 physical interaction relationship: participates_in CCO:I0007711 ! wapl-cspg6-4 physical interaction relationship: participates_in CCO:I0007712 ! wapl-cspg6-5 physical interaction relationship: participates_in CCO:I0007713 ! wapl-cspg6-6 physical interaction relationship: participates_in CCO:I0007714 ! wapl-cspg6-7 physical interaction relationship: participates_in CCO:I0007715 ! wapl-cspg6-9 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013485 ! PDS5A_HUMAN-Phosphothreonine1208 relationship: transforms_into CCO:B0013486 ! PDS5A_HUMAN-Phosphoserine1305 relationship: transforms_into CCO:B0069189 ! PDS5A_HUMAN-Phosphoserine1195 [Term] id: CCO:B0001830 name: Q32M96_HUMAN def: "Platelet-derived growth factor alpha polypeptide" [UniProtKB:Q32M96] xref: EMBL:AAI09247.1 xref: UniProtKB:Q32M96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005287 ! PDGFA_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001831 name: Q3LRW5_HUMAN def: "Cellular tumor antigen p53" [UniProtKB:Q3LRW5] xref: EMBL:ABA29753.1 xref: UniProtKB:Q3LRW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005245 ! TP53_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0001832 name: TBRG1_HUMAN def: "Transforming growth factor beta regulator 1" [UniProtKB:Q3YBR2] synonym: "Nuclear interactor of ARF and Mdm2" EXACT [UniProtKB:Q3YBR2] xref: EMBL:AAI09270.1 xref: EMBL:AAU10523.1 xref: EMBL:AAZ76016.1 xref: EMBL:BAB55177.1 xref: EMBL:BAB84966.1 xref: EMBL:BAD96656.1 xref: EMBL:CAD28450.1 xref: EMBL:CAH10595.1 xref: UniProtKB:Q3YBR2 xref: UniProtKB:Q53GJ5 xref: UniProtKB:Q66ZJ6 xref: UniProtKB:Q69YS7 xref: UniProtKB:Q8TCS4 xref: UniProtKB:Q8TEI4 xref: UniProtKB:Q96SV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005745 ! TBRG1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0001833 name: Q499G5_HUMAN def: "E2F3 protein" [UniProtKB:Q499G5] xref: EMBL:AAH99908.1 xref: UniProtKB:Q499G5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004535 ! E2F3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001834 name: MAP9_HUMAN def: "Microtubule-associated protein 9" [UniProtKB:Q49MG5] synonym: "Aster-associated protein" EXACT [UniProtKB:Q49MG5] xref: EMBL:AAW02921.1 xref: EMBL:AAY40981.1 xref: EMBL:BAB14978.1 xref: EMBL:BAB15017.1 xref: EMBL:CAH18129.1 xref: UniProtKB:Q49MG5 xref: UniProtKB:Q4W5I7 xref: UniProtKB:Q68DU1 xref: UniProtKB:Q9H781 xref: UniProtKB:Q9H7B6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005022 ! MAP9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012761 ! MAP9_HUMAN-Phosphoserine132 [Term] id: CCO:B0001835 name: FBX43_HUMAN def: "F-box only protein 43" [UniProtKB:Q4G163] synonym: "Endogenous meiotic inhibitor 2" EXACT [UniProtKB:Q4G163] xref: UniProtKB:Q4G163 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004624 ! FBXO43_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000117 ! meiosis relationship: transforms_into CCO:B0011866 ! FBX43_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0011867 ! FBX43_HUMAN-Phosphothreonine234 relationship: transforms_into CCO:B0011868 ! FBX43_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0011869 ! FBX43_HUMAN-Phosphotyrosine503 [Term] id: CCO:B0001836 name: PDCD4_HUMAN def: "Programmed cell death protein 4" [UniProtKB:Q53EL6] synonym: "Neoplastic transformation inhibitor protein" EXACT [UniProtKB:Q53EL6] synonym: "Nuclear antigen H731-like" EXACT [UniProtKB:Q53EL6] synonym: "Protein 197/15a" EXACT [UniProtKB:Q53EL6] xref: EMBL:AAB42218.1 xref: EMBL:AAB67706.1 xref: EMBL:AAH15036.1 xref: EMBL:AAH26104.1 xref: EMBL:AAH31049.1 xref: EMBL:BAD97343.1 xref: EMBL:CAH72815.1 xref: EMBL:CAI40095.1 xref: UniProtKB:O15501 xref: UniProtKB:Q53EL6 xref: UniProtKB:Q5VZS6 xref: UniProtKB:Q6PJI5 xref: UniProtKB:Q8TAR5 xref: UniProtKB:Q99834 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005284 ! PDCD4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0013450 ! PDCD4_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0013451 ! PDCD4_HUMAN-Phosphothreonine93 relationship: transforms_into CCO:B0013452 ! PDCD4_HUMAN-Phosphotyrosine152 relationship: transforms_into CCO:B0013453 ! PDCD4_HUMAN-Phosphoserine457 relationship: transforms_into CCO:B0036020 ! PDCD4_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0069161 ! PDCD4_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0069162 ! PDCD4_HUMAN-Phosphoserine80 [Term] id: CCO:B0001837 name: CEP55_HUMAN def: "Centrosomal protein of 55 kDa" [UniProtKB:Q53EZ4] synonym: "Cep55" EXACT [UniProtKB:Q53EZ4] synonym: "Up-regulated in colon cancer 6" EXACT [UniProtKB:Q53EZ4] xref: EMBL:AAH08947.1 xref: EMBL:AAX14687.1 xref: EMBL:BAA91670.1 xref: EMBL:BAD97215.1 xref: EMBL:BAE45243.1 xref: EMBL:CAE45837.1 xref: EMBL:CAH72324.1 xref: UniProtKB:Q32WF5 xref: UniProtKB:Q3MV20 xref: UniProtKB:Q53EZ4 xref: UniProtKB:Q5VY28 xref: UniProtKB:Q6N034 xref: UniProtKB:Q96H32 xref: UniProtKB:Q9NVS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004329 ! CEP55_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005821 ! c10orf3-pom121 physical interaction relationship: participates_in CCO:I0005880 ! c10orf3-tsg101 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011178 ! CEP55_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0011179 ! CEP55_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0011180 ! CEP55_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0064297 ! CEP55_HUMAN-Phosphothreonine430 [Term] id: CCO:B0001838 name: PKHO1_HUMAN def: "Pleckstrin homology domain-containing family O member 1" [UniProtKB:Q53GL0] synonym: "C-Jun-binding protein" EXACT [UniProtKB:Q53GL0] synonym: "Casein kinase 2-interacting protein 1" EXACT [UniProtKB:Q53GL0] synonym: "CK2-interacting protein-1" EXACT [UniProtKB:Q53GL0] synonym: "CKIP-1" EXACT [UniProtKB:Q53GL0] synonym: "JBP" EXACT [UniProtKB:Q53GL0] xref: EMBL:AAF13461.1 xref: EMBL:AAF89644.1 xref: EMBL:AAH10149.1 xref: EMBL:AAH23533.2 xref: EMBL:AAK28027.1 xref: EMBL:AAK71509.1 xref: EMBL:AAQ13826.1 xref: EMBL:BAD96641.1 xref: EMBL:CAI14264.1 xref: EMBL:EAW53580.1 xref: UniProtKB:Q336K5 xref: UniProtKB:Q53GL0 xref: UniProtKB:Q8IZ51 xref: UniProtKB:Q9NRV3 xref: UniProtKB:Q9UL48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005328 ! PLEKHO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001839 name: BOREA_HUMAN def: "Borealin" [UniProtKB:Q53HL2] synonym: "Cell division cycle-associated protein 8" EXACT [UniProtKB:Q53HL2] synonym: "Dasra-B" EXACT [UniProtKB:Q53HL2] synonym: "hDasra-B" EXACT [UniProtKB:Q53HL2] synonym: "Pluripotent embryonic stem cell-related gene 3 protein" EXACT [UniProtKB:Q53HL2] xref: EMBL:AAH00703.1 xref: EMBL:AAH01651.1 xref: EMBL:AAH08079.1 xref: EMBL:AAH16944.1 xref: EMBL:AAR91699.1 xref: EMBL:BAA91629.1 xref: EMBL:BAB13961.1 xref: EMBL:BAB14125.1 xref: EMBL:BAD96269.1 xref: EMBL:BAD96288.1 xref: UniProtKB:Q53HL2 xref: UniProtKB:Q53HN1 xref: UniProtKB:Q96AM3 xref: UniProtKB:Q9NVW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004182 ! CDCA8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010823 ! BOREA_HUMAN-Phosphothreonine106 relationship: transforms_into CCO:B0010824 ! BOREA_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0010825 ! BOREA_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0063950 ! BOREA_HUMAN-Phosphothreonine189 relationship: transforms_into CCO:B0063951 ! BOREA_HUMAN-Phosphothreonine204 [Term] id: CCO:B0001840 name: SGOL2_HUMAN def: "Shugoshin-like 2" [UniProtKB:Q562F6] synonym: "Tripin" EXACT [UniProtKB:Q562F6] xref: EMBL:AAH35764.1 xref: EMBL:AAH48349.1 xref: EMBL:AAH92412.1 xref: EMBL:AAM21971.1 xref: EMBL:AAY24264.1 xref: EMBL:AAY24310.1 xref: EMBL:BAB71617.1 xref: EMBL:BAC04524.1 xref: UniProtKB:Q53RR9 xref: UniProtKB:Q53T20 xref: UniProtKB:Q562F6 xref: UniProtKB:Q86XY4 xref: UniProtKB:Q8IWK2 xref: UniProtKB:Q8IZK1 xref: UniProtKB:Q8N1Q5 xref: UniProtKB:Q96LQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005602 ! SGOL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006348 ! ppp2r5a-sgol2-2 physical interaction relationship: participates_in CCO:I0006353 ! sgol1-pp2r1b-ppp2r5a physical interaction relationship: participates_in CCO:I0006761 ! sgol2-ppp2ca-1 physical interaction relationship: participates_in CCO:I0006762 ! sgol2-ppm1a-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014042 ! SGOL2_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0014043 ! SGOL2_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0014044 ! SGOL2_HUMAN-Phosphothreonine845 relationship: transforms_into CCO:B0070452 ! SGOL2_HUMAN-Phosphoserine1144 relationship: transforms_into CCO:B0070453 ! SGOL2_HUMAN-Phosphoserine1150 relationship: transforms_into CCO:B0070454 ! SGOL2_HUMAN-Phosphoserine1151 [Term] id: CCO:B0001841 name: ESCO2_HUMAN def: "N-acetyltransferase ESCO2" [UniProtKB:Q56NI9] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q56NI9] synonym: "ECO1 homolog 2" EXACT [UniProtKB:Q56NI9] synonym: "Establishment of cohesion 1 homolog 2" EXACT [UniProtKB:Q56NI9] xref: EMBL:AAX68677.1 xref: UniProtKB:Q56NI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004588 ! ESCO2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011765 ! ESCO2_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0048256 ! ESCO2_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0065139 ! ESCO2_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0065140 ! ESCO2_HUMAN-Phosphoserine244 [Term] id: CCO:B0001842 name: BMCC1_HUMAN def: "BNIP2 motif-containing molecule at the C-terminal region 1" [UniProtKB:Q58A63] xref: EMBL:AAH22571.1 xref: EMBL:AAR15150.1 xref: EMBL:AAR15151.1 xref: EMBL:BAA20822.2 xref: EMBL:BAD93351.1 xref: EMBL:CAI10915.2 xref: EMBL:CAI39750.2 xref: UniProtKB:O15073 xref: UniProtKB:Q58A63 xref: UniProtKB:Q5T476 xref: UniProtKB:Q6T2V6 xref: UniProtKB:Q6T2V7 xref: UniProtKB:Q8N665 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004169 ! BMCC1_human relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000313 ! G1 phase relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0010806 ! BMCC1_HUMAN-Phosphoserine217 relationship: transforms_into CCO:B0010807 ! BMCC1_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0010808 ! BMCC1_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0010809 ! BMCC1_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0010810 ! BMCC1_HUMAN-Phosphoserine340 [Term] id: CCO:B0001844 name: Q59FH5_HUMAN def: "Vascular endothelial growth factor variant" [UniProtKB:Q59FH5] xref: EMBL:BAD92722.1 xref: UniProtKB:Q59FH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001845 name: Q59FW7_HUMAN def: "Cyclin H variant" [UniProtKB:Q59FW7] xref: EMBL:BAD92579.1 xref: UniProtKB:Q59FW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001846 name: Q59GE1_HUMAN def: "Septin" [UniProtKB:Q59GE1] xref: EMBL:BAD92405.1 xref: UniProtKB:Q59GE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001847 name: SGOL1_HUMAN def: "Shugoshin-like 1" [UniProtKB:Q5FBB7] synonym: "hSgo1" EXACT [UniProtKB:Q5FBB7] synonym: "Serologically defined breast cancer antigen NY-BR-85" EXACT [UniProtKB:Q5FBB7] xref: EMBL:AAG48266.1 xref: EMBL:AAH01339.2 xref: EMBL:AAH17867.1 xref: EMBL:AAH32696.1 xref: EMBL:BAD89587.1 xref: EMBL:BAD89588.1 xref: EMBL:BAD89589.1 xref: EMBL:BAD89590.1 xref: EMBL:BAD89591.1 xref: EMBL:BAD89592.1 xref: EMBL:BAD91318.1 xref: EMBL:BAD95529.1 xref: EMBL:BAD95530.1 xref: EMBL:BAD95531.1 xref: EMBL:BAD95532.1 xref: EMBL:BAD95533.1 xref: EMBL:BAD95534.1 xref: EMBL:BAD95535.1 xref: EMBL:BAD95536.1 xref: EMBL:BAD95537.1 xref: EMBL:BAD95538.1 xref: EMBL:BAD95539.1 xref: UniProtKB:Q588H5 xref: UniProtKB:Q5FBB4 xref: UniProtKB:Q5FBB5 xref: UniProtKB:Q5FBB6 xref: UniProtKB:Q5FBB7 xref: UniProtKB:Q5FBB8 xref: UniProtKB:Q8N579 xref: UniProtKB:Q8WVL0 xref: UniProtKB:Q9BVA8 xref: UniProtKB:Q9H275 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005601 ! SGOL1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001070 ! mitotic cohesin complex relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0006347 ! ppp2r5d-sgol1-1 physical interaction relationship: participates_in CCO:I0006558 ! ppp2r5a-sgol1-1 physical interaction relationship: participates_in CCO:I0006758 ! sgol1-ppp2ca-1 physical interaction relationship: participates_in CCO:I0006759 ! sgol1-ppm1a-1 physical interaction relationship: participates_in CCO:I0006760 ! sgol1-ppp2r5a-1 physical interaction relationship: participates_in CCO:I0007297 ! sgol1-ppp2r5a-2 colocalization relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000237 ! meiotic chromosome segregation relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0048391 ! SGOL1_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0070450 ! SGOL1_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0070451 ! SGOL1_HUMAN-Phosphoserine507 [Term] id: CCO:B0001848 name: ESCO1_HUMAN def: "N-acetyltransferase ESCO1" [UniProtKB:Q5FWF5] synonym: "CTF7 homolog 1" EXACT [UniProtKB:Q5FWF5] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q5FWF5] synonym: "ECO1 homolog 1" EXACT [UniProtKB:Q5FWF5] synonym: "EFO1p" EXACT [UniProtKB:Q5FWF5] synonym: "ESO1 homolog 1" EXACT [UniProtKB:Q5FWF5] synonym: "Establishment factor-like protein 1" EXACT [UniProtKB:Q5FWF5] synonym: "Establishment of cohesion 1 homolog 1" EXACT [UniProtKB:Q5FWF5] synonym: "hEFO1" EXACT [UniProtKB:Q5FWF5] xref: EMBL:AAH36943.1 xref: EMBL:AAH89426.1 xref: EMBL:BAB67804.1 xref: EMBL:BAC03483.1 xref: EMBL:CAH10584.1 xref: EMBL:CAH10682.1 xref: EMBL:DAA02068.1 xref: UniProtKB:Q5FWF5 xref: UniProtKB:Q69YG4 xref: UniProtKB:Q69YS3 xref: UniProtKB:Q6IMD7 xref: UniProtKB:Q8N3Z5 xref: UniProtKB:Q8NBG2 xref: UniProtKB:Q96PX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004587 ! ESCO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011764 ! ESCO1_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0065138 ! ESCO1_HUMAN-Phosphoserine200 [Term] id: CCO:B0001849 name: TFDP3_HUMAN def: "Transcription factor Dp family member 3" [UniProtKB:Q5H9I0] synonym: "Cancer/testis antigen 30" EXACT [UniProtKB:Q5H9I0] synonym: "CT30" EXACT [UniProtKB:Q5H9I0] synonym: "Hepatocellular carcinoma-associated antigen 661" EXACT [UniProtKB:Q5H9I0] xref: EMBL:AAF37562.2 xref: EMBL:AAH74762.2 xref: EMBL:AAI17337.1 xref: EMBL:AAI26362.1 xref: EMBL:CAI42694.1 xref: EMBL:EAX11773.1 xref: UniProtKB:Q5H9I0 xref: UniProtKB:Q6DK49 xref: UniProtKB:Q9NZ54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005770 ! TFDP3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001854 name: Q5JSB5_HUMAN def: "Transcription factor Dp-1" [UniProtKB:Q5JSB5] xref: EMBL:CAI39788.1 xref: UniProtKB:Q5JSB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005768 ! TFDP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001855 name: Q5JSB6_HUMAN def: "Transcription factor Dp-1" [UniProtKB:Q5JSB6] xref: EMBL:CAI39787.1 xref: UniProtKB:Q5JSB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005768 ! TFDP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001861 name: SPDYC_HUMAN def: "Speedy protein C" [UniProtKB:Q5MJ68] synonym: "hSpy/Ringo C" EXACT [UniProtKB:Q5MJ68] synonym: "Rapid inducer of G2/M progression in oocytes C" EXACT [UniProtKB:Q5MJ68] synonym: "RINGO C" EXACT [UniProtKB:Q5MJ68] xref: EMBL:AAW30396.1 xref: UniProtKB:Q5MJ68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005657 ! SPDYC_human relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001862 name: SPDYA_HUMAN def: "Speedy protein A" [UniProtKB:Q5MJ70] synonym: "hSpy/Ringo A" EXACT [UniProtKB:Q5MJ70] synonym: "Rapid inducer of G2/M progression in oocytes A" EXACT [UniProtKB:Q5MJ70] synonym: "RINGO A" EXACT [UniProtKB:Q5MJ70] synonym: "Speedy-1" EXACT [UniProtKB:Q5MJ70] synonym: "Spy1" EXACT [UniProtKB:Q5MJ70] xref: EMBL:AAH93005.1 xref: EMBL:AAW30394.1 xref: EMBL:AAW30395.1 xref: EMBL:AAY24014.1 xref: UniProtKB:Q53R05 xref: UniProtKB:Q5MJ69 xref: UniProtKB:Q5MJ70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005656 ! SPDYA_human relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0001867 name: Q5T179_HUMAN def: "CDC28 protein kinase regulatory subunit 1B" [UniProtKB:Q5T179] xref: EMBL:CAI13255.1 xref: UniProtKB:Q5T179 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004364 ! CKS1B_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001872 name: Q5T317_HUMAN def: "p53 regulated PA26 nuclear protein (PA26-T1)" [UniProtKB:Q5T317] xref: EMBL:CAI16719.1 xref: UniProtKB:Q5T317 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005997 ! RP11-787I22.2-003_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001875 name: HECD3_HUMAN def: "Probable E3 ubiquitin-protein ligase HECTD3" [UniProtKB:Q5T447] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q5T447] synonym: "HECT domain-containing protein 3" EXACT [UniProtKB:Q5T447] xref: EMBL:AAH19105.1 xref: EMBL:BAB15015.1 xref: EMBL:CAI16437.1 xref: EMBL:CAI16438.1 xref: UniProtKB:Q5T447 xref: UniProtKB:Q5T448 xref: UniProtKB:Q9H783 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004797 ! HECTD3_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition [Term] id: CCO:B0001879 name: AVPI1_HUMAN def: "Arginine vasopressin-induced protein 1" [UniProtKB:Q5T686] synonym: "AVP-induced protein 1" EXACT [UniProtKB:Q5T686] xref: EMBL:AAG17261.1 xref: EMBL:AAG44474.1 xref: EMBL:AAH00877.1 xref: EMBL:BAD96213.1 xref: EMBL:BAD96819.1 xref: EMBL:CAI15464.1 xref: UniProtKB:Q53G32 xref: UniProtKB:Q5T686 xref: UniProtKB:Q9H2R9 xref: UniProtKB:Q9HBN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004131 ! AVPI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000411 ! activation of MAPK activity [Term] id: CCO:B0001882 name: UT14C_HUMAN def: "U3 small nucleolar RNA-associated protein 14 homolog C" [UniProtKB:Q5TAP6] xref: EMBL:AAH89407.1 xref: EMBL:BAA13396.2 xref: EMBL:CAI12891.1 xref: UniProtKB:Q5FWG3 xref: UniProtKB:Q5TAP6 xref: UniProtKB:Q92555 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005890 ! UTP14C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002175 ! small-subunit processome relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0001883 name: QN1_HUMAN def: "Protein QN1 homolog" [UniProtKB:Q5TB80] xref: EMBL:AAH63632.1 xref: EMBL:BAA76853.2 xref: EMBL:CAI22698.2 xref: EMBL:CAO03537.1 xref: UniProtKB:A6PVL7 xref: UniProtKB:A6PVL8 xref: UniProtKB:Q5TB80 xref: UniProtKB:Q6P475 xref: UniProtKB:Q9Y2L2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005405 ! KIAA1009_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013653 ! QN1_HUMAN-Phosphoserine770 relationship: transforms_into CCO:B0013654 ! QN1_HUMAN-Phosphoserine776 [Term] id: CCO:B0001884 name: Q5TBT1_HUMAN def: "Dystonin" [UniProtKB:Q5TBT1] xref: EMBL:CAI14342.1 xref: EMBL:CAI14988.1 xref: EMBL:CAI16608.1 xref: EMBL:CAI20331.1 xref: EMBL:CAI22043.1 xref: UniProtKB:Q5TBT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004183 ! DST_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006581 ! dtnbp1-bpag1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001885 name: Q5TBT2_HUMAN def: "Dystonin" [UniProtKB:Q5TBT2] xref: EMBL:CAI14341.1 xref: EMBL:CAI14989.1 xref: EMBL:CAI16609.1 xref: EMBL:CAI20330.1 xref: EMBL:CAI22044.1 xref: UniProtKB:Q5TBT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004183 ! DST_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001886 name: Q5TCH6_HUMAN def: "SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)" [UniProtKB:Q5TCH6] xref: EMBL:CAI21519.2 xref: UniProtKB:Q5TCH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005664 ! SPO11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0001887 name: Q5TCH7_HUMAN def: "SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)" [UniProtKB:Q5TCH7] xref: EMBL:CAI21520.1 xref: UniProtKB:Q5TCH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005664 ! SPO11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0001888 name: Q5TCY3_HUMAN def: "Novel protein (P53-associated parkin-like cytoplasmic protein, isoform CRA_a)" [UniProtKB:Q5TCY3] xref: EMBL:CAI20204.1 xref: EMBL:EAX04163.1 xref: UniProtKB:Q5TCY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006002 ! RP3-330M21.2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition [Term] id: CCO:B0001894 name: LIN9_HUMAN def: "Lin-9 homolog" [UniProtKB:Q5TKA1] synonym: "Beta subunit-associated regulator of apoptosis" EXACT [UniProtKB:Q5TKA1] synonym: "hLin-9" EXACT [UniProtKB:Q5TKA1] synonym: "huLin-9" EXACT [UniProtKB:Q5TKA1] synonym: "pRB-associated protein" EXACT [UniProtKB:Q5TKA1] synonym: "TUDOR gene similar protein" EXACT [UniProtKB:Q5TKA1] synonym: "Type I interferon receptor beta chain-associated protein" EXACT [UniProtKB:Q5TKA1] xref: EMBL:AAH43444.1 xref: EMBL:AAH45625.1 xref: EMBL:AAQ13710.1 xref: EMBL:AAQ13711.1 xref: EMBL:AAV41873.1 xref: EMBL:BAC86475.1 xref: EMBL:CAD97871.1 xref: UniProtKB:Q5TKA1 xref: UniProtKB:Q5U5L8 xref: UniProtKB:Q5U7E1 xref: UniProtKB:Q6PI55 xref: UniProtKB:Q6ZTV4 xref: UniProtKB:Q7Z3J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004981 ! LIN9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0012701 ! LIN9_HUMAN-Phosphoserine309 relationship: transforms_into CCO:B0048311 ! LIN9_HUMAN-Phosphoserine321 relationship: transforms_into CCO:B0067674 ! LIN9_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0067675 ! LIN9_HUMAN-Phosphothreonine297 relationship: transforms_into CCO:B0067676 ! LIN9_HUMAN-Phosphothreonine304 [Term] id: CCO:B0001895 name: CROCC_HUMAN def: "Rootletin" [UniProtKB:Q5TZA2] synonym: "Ciliary rootlet coiled-coil protein" EXACT [UniProtKB:Q5TZA2] xref: EMBL:AAP85633.1 xref: EMBL:ABA43896.1 xref: EMBL:BAA32290.2 xref: EMBL:CAH70055.1 xref: EMBL:CAI20363.1 xref: EMBL:DAA05505.1 xref: UniProtKB:Q2VHY3 xref: UniProtKB:Q5TZA2 xref: UniProtKB:Q66GT7 xref: UniProtKB:Q7Z2L4 xref: UniProtKB:Q7Z5D7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004399 ! CROCC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011349 ! CROCC_HUMAN-Phosphoserine1619 [Term] id: CCO:B0001896 name: Q5TZP9_HUMAN def: "Cyclin B1" [UniProtKB:Q5TZP9] xref: EMBL:AAV38930.1 xref: UniProtKB:Q5TZP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001897 name: RIF1_HUMAN def: "Telomere-associated protein RIF1" [UniProtKB:Q5UIP0] synonym: "Rap1-interacting factor 1 homolog" EXACT [UniProtKB:Q5UIP0] xref: EMBL:AAB50209.1 xref: EMBL:AAS94233.1 xref: EMBL:AAT40745.1 xref: EMBL:AAV51401.1 xref: EMBL:AAV51402.1 xref: EMBL:AAV51403.1 xref: EMBL:AAV51404.1 xref: EMBL:BAA91705.1 xref: EMBL:BAB14313.1 xref: EMBL:BAB14792.1 xref: EMBL:BAB85058.1 xref: EMBL:CAB45727.1 xref: EMBL:CAI45961.1 xref: UniProtKB:A6NC27 xref: UniProtKB:Q5H9R3 xref: UniProtKB:Q5UIP0 xref: UniProtKB:Q5UIP2 xref: UniProtKB:Q66YK6 xref: UniProtKB:Q6PRU2 xref: UniProtKB:Q8TE94 xref: UniProtKB:Q99772 xref: UniProtKB:Q9H830 xref: UniProtKB:Q9H9B9 xref: UniProtKB:Q9NVP5 xref: UniProtKB:Q9Y4R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005489 ! RIF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007984 ! cpe-rif1 physical interaction relationship: participates_in CCO:I0007990 ! rpa2-rif1 physical interaction relationship: participates_in CCO:I0007991 ! selenbp1-rif1 physical interaction relationship: participates_in CCO:I0008002 ! cdc42-rif1 physical interaction relationship: participates_in CCO:I0008005 ! cdkn2c-rif1 physical interaction relationship: participates_in CCO:I0008008 ! cox17-rif1 physical interaction relationship: participates_in CCO:I0008014 ! hrmt1l2-rif1 physical interaction relationship: participates_in CCO:I0008015 ! hspe1-rif1 physical interaction relationship: participates_in CCO:I0008017 ! lama4-rif1 physical interaction relationship: participates_in CCO:I0008024 ! mrps12-rif1 physical interaction relationship: participates_in CCO:I0008025 ! naca-rif1 physical interaction relationship: participates_in CCO:I0008027 ! np-rif1 physical interaction relationship: participates_in CCO:I0008028 ! pafah1b3-rif1 physical interaction relationship: participates_in CCO:I0008031 ! polr2c-rif1 physical interaction relationship: participates_in CCO:I0008032 ! polr3f-rif1 physical interaction relationship: participates_in CCO:I0008036 ! psmd11-rif1 physical interaction relationship: participates_in CCO:I0008038 ! psmd2-rif1 physical interaction relationship: participates_in CCO:I0008042 ! rfc5-rif1 physical interaction relationship: participates_in CCO:I0008046 ! rplp1-rif1 physical interaction relationship: participates_in CCO:I0008047 ! sat-rif1 physical interaction relationship: participates_in CCO:I0008050 ! serpinb9-rif1 physical interaction relationship: participates_in CCO:I0008053 ! smn1-rif1 physical interaction relationship: participates_in CCO:I0008058 ! tk1-rif1 physical interaction relationship: participates_in CCO:I0008062 ! znf24-rif1 physical interaction relationship: participates_in CCO:I0008063 ! akr1c3-rif1 physical interaction relationship: participates_in CCO:I0008064 ! ankrd24-rif1 physical interaction relationship: participates_in CCO:I0008067 ! arl3-rif1 physical interaction relationship: participates_in CCO:I0008073 ! bmi1-rif1 physical interaction relationship: participates_in CCO:I0008075 ! cbx1-rif1 physical interaction relationship: participates_in CCO:I0008086 ! cetn3-rif1 physical interaction relationship: participates_in CCO:I0008088 ! ckmt2-rif1 physical interaction relationship: participates_in CCO:I0008101 ! dnmt2-rif1 physical interaction relationship: participates_in CCO:I0008107 ! fxr1-rif1 physical interaction relationship: participates_in CCO:I0008113 ! gstm4-rif1 physical interaction relationship: participates_in CCO:I0008116 ! hbxip-rif1 physical interaction relationship: participates_in CCO:I0008117 ! hla_dqa1-rif1 physical interaction relationship: participates_in CCO:I0008119 ! hmgb1-rif1 physical interaction relationship: participates_in CCO:I0008120 ! hmox2-rif1 physical interaction relationship: participates_in CCO:I0008123 ! hspb1-rif1 physical interaction relationship: participates_in CCO:I0008125 ! id2-rif1 physical interaction relationship: participates_in CCO:I0008134 ! mphosph6-rif1 physical interaction relationship: participates_in CCO:I0008140 ! pcdha4-rif1 physical interaction relationship: participates_in CCO:I0008141 ! pdcd5-rif1 physical interaction relationship: participates_in CCO:I0008146 ! pfdn1-rif1 physical interaction relationship: participates_in CCO:I0008148 ! pfn1-rif1 physical interaction relationship: participates_in CCO:I0008153 ! prei3-rif1 physical interaction relationship: participates_in CCO:I0008154 ! psg9-rif1 physical interaction relationship: participates_in CCO:I0008156 ! rbm5-rif1 physical interaction relationship: participates_in CCO:I0008159 ! s100a8-rif1 physical interaction relationship: participates_in CCO:I0008164 ! snrpn-rif1 physical interaction relationship: participates_in CCO:I0008169 ! sult1e1-rif1 physical interaction relationship: participates_in CCO:I0008175 ! tmsb4x-rif1 physical interaction relationship: participates_in CCO:I0008186 ! vim-rif1 physical interaction relationship: participates_in CCO:I0008188 ! klhlx-rif1 physical interaction relationship: participates_in CCO:I0008189 ! arhh-rif1 physical interaction relationship: participates_in CCO:I0008192 ! atf3-rif1 physical interaction relationship: participates_in CCO:I0008193 ! atp1b1-rif1 physical interaction relationship: participates_in CCO:I0008203 ! brms1-rif1 physical interaction relationship: participates_in CCO:I0008205 ! c19orf14-rif1 physical interaction relationship: participates_in CCO:I0008217 ! cradd-rif1 physical interaction relationship: participates_in CCO:I0008231 ! ethe1-rif1 physical interaction relationship: participates_in CCO:I0008241 ! smpd3-rif1 physical interaction relationship: participates_in CCO:I0008244 ! gc-rif1 physical interaction relationship: participates_in CCO:I0008249 ! hspb3-rif1 physical interaction relationship: participates_in CCO:I0008250 ! hspbp1-rif1 physical interaction relationship: participates_in CCO:I0008252 ! itgb3bp-rif1 physical interaction relationship: participates_in CCO:I0008254 ! kibra-rif1 physical interaction relationship: participates_in CCO:I0008262 ! mad2l1bp-rif1 physical interaction relationship: participates_in CCO:I0008267 ! mllt3-rif1 physical interaction relationship: participates_in CCO:I0008271 ! mnat1-rif1 physical interaction relationship: participates_in CCO:I0008276 ! mrps6-rif1 physical interaction relationship: participates_in CCO:I0008283 ! nhp2l1-rif1 physical interaction relationship: participates_in CCO:I0008284 ! paep-rif1 physical interaction relationship: participates_in CCO:I0008290 ! plekha4-rif1 physical interaction relationship: participates_in CCO:I0008298 ! pqbp1-rif1 physical interaction relationship: participates_in CCO:I0008306 ! rab27a-rif1 physical interaction relationship: participates_in CCO:I0008314 ! rit1-rif1 physical interaction relationship: participates_in CCO:I0008315 ! rnf10-rif1 physical interaction relationship: participates_in CCO:I0008317 ! rpl37a-rif1 physical interaction relationship: participates_in CCO:I0008318 ! rrm1-rif1 physical interaction relationship: participates_in CCO:I0008323 ! spg7-rif1 physical interaction relationship: participates_in CCO:I0008326 ! stx5a-rif1 physical interaction relationship: participates_in CCO:I0008336 ! tdgf1-rif1 physical interaction relationship: participates_in CCO:I0008339 ! tgif-rif1 physical interaction relationship: participates_in CCO:I0008340 ! tm4sf6-rif1 physical interaction relationship: participates_in CCO:I0008341 ! tnfrsf6-rif1 physical interaction relationship: participates_in CCO:I0008346 ! trbv21_1-rif1 physical interaction relationship: participates_in CCO:I0008349 ! ube2v2-rif1 physical interaction relationship: participates_in CCO:I0008362 ! boc-rif1 physical interaction relationship: participates_in CCO:I0008402 ! klk10-rif1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0013860 ! RIF1_HUMAN-Phosphoserine782 relationship: transforms_into CCO:B0013861 ! RIF1_HUMAN-Phosphoserine1454 relationship: transforms_into CCO:B0013862 ! RIF1_HUMAN-Phosphoserine1513 relationship: transforms_into CCO:B0013863 ! RIF1_HUMAN-Phosphothreonine1518 relationship: transforms_into CCO:B0013864 ! RIF1_HUMAN-Phosphoserine1542 relationship: transforms_into CCO:B0013865 ! RIF1_HUMAN-Phosphoserine1579 relationship: transforms_into CCO:B0013866 ! RIF1_HUMAN-Phosphoserine1688 relationship: transforms_into CCO:B0013867 ! RIF1_HUMAN-Phosphoserine1851 relationship: transforms_into CCO:B0013868 ! RIF1_HUMAN-Phosphoserine2161 relationship: transforms_into CCO:B0013869 ! RIF1_HUMAN-Phosphoserine2243 relationship: transforms_into CCO:B0070025 ! RIF1_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0070026 ! RIF1_HUMAN-Phosphothreonine409 relationship: transforms_into CCO:B0070027 ! RIF1_HUMAN-Phosphoserine1162 relationship: transforms_into CCO:B0070028 ! RIF1_HUMAN-Phosphoserine1236 relationship: transforms_into CCO:B0070029 ! RIF1_HUMAN-Phosphoserine1238 relationship: transforms_into CCO:B0070030 ! RIF1_HUMAN-Phosphoserine1422 relationship: transforms_into CCO:B0070031 ! RIF1_HUMAN-Phosphoserine1552 relationship: transforms_into CCO:B0070032 ! RIF1_HUMAN-Phosphoserine1554 relationship: transforms_into CCO:B0070033 ! RIF1_HUMAN-Phosphoserine1576 relationship: transforms_into CCO:B0070034 ! RIF1_HUMAN-Phosphoserine1616 relationship: transforms_into CCO:B0070035 ! RIF1_HUMAN-Phosphoserine1693 relationship: transforms_into CCO:B0070036 ! RIF1_HUMAN-Phosphoserine1810 relationship: transforms_into CCO:B0070037 ! RIF1_HUMAN-Phosphoserine2144 relationship: transforms_into CCO:B0070038 ! RIF1_HUMAN-Phosphoserine2172 relationship: transforms_into CCO:B0070039 ! RIF1_HUMAN-Phosphoserine2176 relationship: transforms_into CCO:B0070040 ! RIF1_HUMAN-Phosphoserine2196 relationship: transforms_into CCO:B0070041 ! RIF1_HUMAN-Phosphoserine2205 relationship: transforms_into CCO:B0070042 ! RIF1_HUMAN-Phosphoserine2260 relationship: transforms_into CCO:B0070043 ! RIF1_HUMAN-Phosphoserine2265 relationship: transforms_into CCO:B0070044 ! RIF1_HUMAN-Phosphoserine2339 relationship: transforms_into CCO:B0070045 ! RIF1_HUMAN-Phosphoserine2391 relationship: transforms_into CCO:B0070046 ! RIF1_HUMAN-Phosphoserine2393 relationship: transforms_into CCO:B0070047 ! RIF1_HUMAN-Phosphoserine2465 relationship: transforms_into CCO:B0070048 ! RIF1_HUMAN-Phosphoserine2471 [Term] id: CCO:B0001898 name: GFI1B_HUMAN def: "Zinc finger protein Gfi-1b" [UniProtKB:Q5VTD9] synonym: "Growth factor independent protein 1B" EXACT [UniProtKB:Q5VTD9] synonym: "Potential regulator of CDKN1A translocated in CML" EXACT [UniProtKB:Q5VTD9] xref: EMBL:AAD08672.1 xref: EMBL:AAH43371.1 xref: EMBL:AAR06639.1 xref: EMBL:CAG38783.1 xref: EMBL:CAH73618.1 xref: EMBL:CAH73619.1 xref: EMBL:EAW88025.1 xref: UniProtKB:O95270 xref: UniProtKB:Q5VTD8 xref: UniProtKB:Q5VTD9 xref: UniProtKB:Q6FHZ2 xref: UniProtKB:Q6T888 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004694 ! GFI1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006216 ! cenpj-gfi1b physical interaction relationship: participates_in CCO:I0006217 ! gfi1b-jag2 physical interaction relationship: participates_in CCO:I0006218 ! gfi1b-nell2 physical interaction relationship: participates_in CCO:I0006650 ! znrd1-gfi1b physical interaction relationship: participates_in CCO:I0006658 ! gfi1b-cops5 physical interaction relationship: participates_in CCO:I0006659 ! gfi1b-ccdc85b physical interaction relationship: participates_in CCO:I0006660 ! gfi1b-begain-1 physical interaction relationship: participates_in CCO:I0006661 ! gfi1b-ushbp1 physical interaction relationship: participates_in CCO:I0007630 ! gfi1b-actn1 physical interaction relationship: participates_in CCO:I0007631 ! gfi1b-agrn physical interaction relationship: participates_in CCO:I0007632 ! gfi1b-becn1 physical interaction relationship: participates_in CCO:I0007633 ! gfi1b-brca1 physical interaction relationship: participates_in CCO:I0007634 ! gfi1b-bre physical interaction relationship: participates_in CCO:I0007635 ! gfi1b-c20orf12 physical interaction relationship: participates_in CCO:I0007636 ! gfi1b-cenpb physical interaction relationship: participates_in CCO:I0007637 ! gfi1b-cenpj physical interaction relationship: participates_in CCO:I0007638 ! gfi1b-dkfzp586m1819 physical interaction relationship: participates_in CCO:I0007639 ! gfi1b-dtna physical interaction relationship: participates_in CCO:I0007640 ! gfi1b-efemp1 physical interaction relationship: participates_in CCO:I0007641 ! gfi1b-efemp2 physical interaction relationship: participates_in CCO:I0007642 ! gfi1b-megf6 physical interaction relationship: participates_in CCO:I0007643 ! gfi1b-megf8 physical interaction relationship: participates_in CCO:I0007644 ! gfi1b-egfl7 physical interaction relationship: participates_in CCO:I0007645 ! gfi1b-fbln1 physical interaction relationship: participates_in CCO:I0007646 ! gfi1b-grip2 physical interaction relationship: participates_in CCO:I0007647 ! gfi1b-grn physical interaction relationship: participates_in CCO:I0007648 ! gfi1b-hecw1 physical interaction relationship: participates_in CCO:I0007649 ! gfi1b-hgs physical interaction relationship: participates_in CCO:I0007650 ! gfi1b-hnrpk physical interaction relationship: participates_in CCO:I0007651 ! gfi1b-hom_tes_103 physical interaction relationship: participates_in CCO:I0007652 ! gfi1b-hspg2 physical interaction relationship: participates_in CCO:I0007653 ! gfi1b-jag2-1 physical interaction relationship: participates_in CCO:I0007654 ! gfi1b-begain physical interaction relationship: participates_in CCO:I0007655 ! gfi1b-anks3 physical interaction relationship: participates_in CCO:I0007656 ! gfi1b-kif17 physical interaction relationship: participates_in CCO:I0007657 ! gfi1b-lamb1 physical interaction relationship: participates_in CCO:I0007658 ! gfi1b-lzts2 physical interaction relationship: participates_in CCO:I0007659 ! gfi1b-matr3 physical interaction relationship: participates_in CCO:I0007660 ! gfi1b-mid2 physical interaction relationship: participates_in CCO:I0007661 ! gfi1b-mon1a physical interaction relationship: participates_in CCO:I0007662 ! gfi1b-myh14 physical interaction relationship: participates_in CCO:I0007663 ! gfi1b-nelf physical interaction relationship: participates_in CCO:I0007664 ! gfi1b-nell1 physical interaction relationship: participates_in CCO:I0007665 ! gfi1b-nell2-1 physical interaction relationship: participates_in CCO:I0007666 ! gfi1b-notch1 physical interaction relationship: participates_in CCO:I0007667 ! gfi1b-pde4dip physical interaction relationship: participates_in CCO:I0007668 ! gfi1b-enh physical interaction relationship: participates_in CCO:I0007669 ! gfi1b-pdzk4 physical interaction relationship: participates_in CCO:I0007670 ! gfi1b-phc2 physical interaction relationship: participates_in CCO:I0007671 ! gfi1b-prkcabp physical interaction relationship: participates_in CCO:I0007672 ! gfi1b-rab11fip4 physical interaction relationship: participates_in CCO:I0007673 ! gfi1b-rchy1 physical interaction relationship: participates_in CCO:I0007674 ! gfi1b-rfp physical interaction relationship: participates_in CCO:I0007675 ! gfi1b-rint1 physical interaction relationship: participates_in CCO:I0007676 ! gfi1b-rnf31 physical interaction relationship: participates_in CCO:I0007678 ! gfi1b-taf1 physical interaction relationship: participates_in CCO:I0007679 ! gfi1b-tmf1 physical interaction relationship: participates_in CCO:I0007680 ! gfi1b-trip6 physical interaction relationship: participates_in CCO:I0007681 ! gfi1b-vsnl1 physical interaction relationship: participates_in CCO:I0007682 ! gfi1b-actn1-1 physical interaction relationship: participates_in CCO:I0007683 ! gfi1b-aes physical interaction relationship: participates_in CCO:I0007684 ! gfi1b-atxn2 physical interaction relationship: participates_in CCO:I0007685 ! gfi1b-dnaja3 physical interaction relationship: participates_in CCO:I0007686 ! gfi1b-efemp1-1 physical interaction relationship: participates_in CCO:I0007687 ! gfi1b-efemp2-1 physical interaction relationship: participates_in CCO:I0007688 ! gfi1b-fbln5 physical interaction relationship: participates_in CCO:I0007689 ! gfi1b-jub physical interaction relationship: participates_in CCO:I0007690 ! gfi1b-prkcabp-1 physical interaction relationship: participates_in CCO:I0007691 ! gfi1b-psma3 physical interaction relationship: participates_in CCO:I0007692 ! gfi1b-traf1 physical interaction relationship: participates_in CCO:I0007693 ! gfi1b-trip6-1 physical interaction relationship: participates_in CCO:I0007694 ! gfi1b-txndc11 physical interaction relationship: participates_in CCO:P0000024 ! G1-specific transcription in mitotic cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011929 ! GFI1B_HUMAN-Phosphoserine261 [Term] id: CCO:B0001899 name: DAB2P_HUMAN def: "Disabled homolog 2-interacting protein" [UniProtKB:Q5VWQ8] synonym: "ASK-interacting protein 1" EXACT [UniProtKB:Q5VWQ8] synonym: "DAB2 interaction protein" EXACT [UniProtKB:Q5VWQ8] synonym: "DAB2-interacting protein" EXACT [UniProtKB:Q5VWQ8] xref: EMBL:AAI46763.1 xref: EMBL:AAK50336.1 xref: EMBL:AAM00371.1 xref: EMBL:BAB21834.2 xref: EMBL:CAH72155.3 xref: EMBL:CAH72158.1 xref: EMBL:EAW87503.1 xref: UniProtKB:A6H8V2 xref: UniProtKB:A6NHI9 xref: UniProtKB:Q5VWQ8 xref: UniProtKB:Q8TDL2 xref: UniProtKB:Q96SE1 xref: UniProtKB:Q9C0C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004433 ! DAB2IP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0011422 ! DAB2P_HUMAN-Phosphoserine702 relationship: transforms_into CCO:B0064614 ! DAB2P_HUMAN-Phosphoserine992 relationship: transforms_into CCO:B0064615 ! DAB2P_HUMAN-Phosphoserine995 [Term] id: CCO:B0001900 name: Q5VXJ5_HUMAN def: "Synaptonemal complex protein 1" [UniProtKB:Q5VXJ5] xref: EMBL:CAH72848.1 xref: UniProtKB:Q5VXJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005710 ! SYCP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000122 ! synaptonemal complex relationship: participates_in CCO:P0000121 ! synaptonemal complex assembly [Term] id: CCO:B0001901 name: Q5W161_HUMAN def: "Septin" [UniProtKB:Q5W161] xref: EMBL:CAH72053.1 xref: UniProtKB:Q5W161 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006003 ! RP11-291L22.2-003_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001902 name: POLS_HUMAN def: "DNA polymerase sigma" [UniProtKB:Q5XG87] synonym: "DNA polymerase kappa" EXACT [UniProtKB:Q5XG87] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q5XG87] synonym: "LAK-1" EXACT [UniProtKB:Q5XG87] synonym: "Topoisomerase-related function protein 4-1" EXACT [UniProtKB:Q5XG87] synonym: "TRF4-1" EXACT [UniProtKB:Q5XG87] xref: EMBL:AAD45198.1 xref: EMBL:AAH84567.2 xref: EMBL:AAI17138.1 xref: EMBL:AAI26107.1 xref: EMBL:AAT38110.1 xref: EMBL:BAA24434.2 xref: UniProtKB:O43289 xref: UniProtKB:Q17RZ1 xref: UniProtKB:Q5XG87 xref: UniProtKB:Q9Y6C1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005354 ! POLS_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0005823 ! SMC protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000076 ! sister chromatid cohesion relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001903 name: STEA3_HUMAN def: "Metalloreductase STEAP3" [UniProtKB:Q658P3] synonym: "Dudulin-2" EXACT [UniProtKB:Q658P3] synonym: "EC 1.16.1.-" EXACT [UniProtKB:Q658P3] synonym: "hpHyde" EXACT [UniProtKB:Q658P3] synonym: "hTSAP6" EXACT [UniProtKB:Q658P3] synonym: "pHyde" EXACT [UniProtKB:Q658P3] synonym: "Six-transmembrane epithelial antigen of prostate 3" EXACT [UniProtKB:Q658P3] synonym: "Tumor suppressor-activated pathway protein 6" EXACT [UniProtKB:Q658P3] xref: EMBL:AAH42150.1 xref: EMBL:AAH95421.2 xref: EMBL:AAK50538.1 xref: EMBL:AAL78206.1 xref: EMBL:AAM08128.1 xref: EMBL:AAM45136.1 xref: EMBL:AAO38238.1 xref: EMBL:AAQ04065.1 xref: EMBL:AAX88963.1 xref: EMBL:AAY14872.1 xref: EMBL:BAA91839.1 xref: EMBL:CAD97986.1 xref: EMBL:CAH56204.1 xref: UniProtKB:Q4VBR2 xref: UniProtKB:Q4ZG36 xref: UniProtKB:Q53SQ8 xref: UniProtKB:Q658P3 xref: UniProtKB:Q7Z389 xref: UniProtKB:Q86SF6 xref: UniProtKB:Q8NEW6 xref: UniProtKB:Q8TDP3 xref: UniProtKB:Q8TF03 xref: UniProtKB:Q9NVB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005690 ! STEAP3_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0014249 ! STEA3_HUMAN-Phosphoserine20 [Term] id: CCO:B0001904 name: KCD11_HUMAN def: "BTB/POZ domain-containing protein KCTD11" [UniProtKB:Q693B1] xref: EMBL:AAI10599.1 xref: EMBL:AAT75307.1 xref: UniProtKB:Q693B1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004933 ! KCTD11_human relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0001905 name: CDCA2_HUMAN def: "Cell division cycle-associated protein 2" [UniProtKB:Q69YH5] synonym: "Recruits PP1 onto mitotic chromatin at anaphase protein" EXACT [UniProtKB:Q69YH5] synonym: "Repo-Man" EXACT [UniProtKB:Q69YH5] xref: EMBL:AAH36214.1 xref: EMBL:AAH63651.1 xref: EMBL:AAH85609.1 xref: EMBL:AAI04451.1 xref: EMBL:AAI04452.1 xref: EMBL:BAC05374.1 xref: EMBL:CAH10577.1 xref: EMBL:CAH10585.1 xref: UniProtKB:Q3SX74 xref: UniProtKB:Q4G0W0 xref: UniProtKB:Q5RKN0 xref: UniProtKB:Q69YH5 xref: UniProtKB:Q69YI4 xref: UniProtKB:Q6P464 xref: UniProtKB:Q8N7C1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004295 ! CDCA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011088 ! CDCA2_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0011089 ! CDCA2_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0011090 ! CDCA2_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0011091 ! CDCA2_HUMAN-Phosphoserine401 relationship: transforms_into CCO:B0064200 ! CDCA2_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0064201 ! CDCA2_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0064202 ! CDCA2_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0064203 ! CDCA2_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0064204 ! CDCA2_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0064205 ! CDCA2_HUMAN-Phosphothreonine313 relationship: transforms_into CCO:B0064206 ! CDCA2_HUMAN-Phosphoserine408 relationship: transforms_into CCO:B0064207 ! CDCA2_HUMAN-Phosphothreonine413 relationship: transforms_into CCO:B0064208 ! CDCA2_HUMAN-Phosphoserine592 relationship: transforms_into CCO:B0064209 ! CDCA2_HUMAN-Phosphothreonine604 relationship: transforms_into CCO:B0064210 ! CDCA2_HUMAN-Phosphoserine727 relationship: transforms_into CCO:B0064211 ! CDCA2_HUMAN-Phosphoserine757 [Term] id: CCO:B0001906 name: CYTSA_HUMAN def: "Cytospin-A" [UniProtKB:Q69YQ0] synonym: "Renal carcinoma antigen NY-REN-22" EXACT [UniProtKB:Q69YQ0] synonym: "SPECC1-like protein" EXACT [UniProtKB:Q69YQ0] xref: EMBL:AAX84184.1 xref: EMBL:BAA21574.1 xref: EMBL:CAH10609.1 xref: UniProtKB:O15081 xref: UniProtKB:Q69YQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004432 ! SPECC1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011420 ! CYTSA_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0011421 ! CYTSA_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0048216 ! CYTSA_HUMAN-Phosphoserine881 relationship: transforms_into CCO:B0064611 ! CYTSA_HUMAN-Phosphoserine832 relationship: transforms_into CCO:B0064612 ! CYTSA_HUMAN-Phosphoserine868 relationship: transforms_into CCO:B0064613 ! CYTSA_HUMAN-Phosphothreonine874 [Term] id: CCO:B0001907 name: WBP2L_HUMAN def: "Postacrosomal sheath WW domain-binding protein" [UniProtKB:Q6ICG8] synonym: "WW domain-binding protein 2-like" EXACT [UniProtKB:Q6ICG8] xref: EMBL:AAH22546.1 xref: EMBL:AAH22549.1 xref: EMBL:AAQ02873.1 xref: EMBL:CAG30286.1 xref: EMBL:CAI41694.1 xref: UniProtKB:A3KFF7 xref: UniProtKB:Q6ICG8 xref: UniProtKB:Q8TBF0 xref: UniProtKB:Q8TBF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005913 ! WBP2NL_human relationship: has_function CCO:F0007999 ! WW domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001504 ! perinuclear theca relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0001908 name: NIPBL_HUMAN def: "Nipped-B-like protein" [UniProtKB:Q6KC79] synonym: "Delangin" EXACT [UniProtKB:Q6KC79] synonym: "SCC2 homolog" EXACT [UniProtKB:Q6KC79] xref: EMBL:AAH33847.1 xref: EMBL:BAA77335.1 xref: EMBL:BAA77349.1 xref: EMBL:BAC86701.1 xref: EMBL:CAD98051.1 xref: EMBL:CAD98052.1 xref: EMBL:CAE45790.1 xref: EMBL:CAF25290.1 xref: EMBL:CAG26691.1 xref: UniProtKB:Q6KC79 xref: UniProtKB:Q6KCD6 xref: UniProtKB:Q6N080 xref: UniProtKB:Q6ZT92 xref: UniProtKB:Q7Z2E6 xref: UniProtKB:Q8N4M5 xref: UniProtKB:Q9Y6Y3 xref: UniProtKB:Q9Y6Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005196 ! NIPBL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008465 ! dbn1-nipbl physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0013180 ! NIPBL_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0013181 ! NIPBL_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0013182 ! NIPBL_HUMAN-Phosphoserine553 relationship: transforms_into CCO:B0013183 ! NIPBL_HUMAN-Phosphothreonine558 relationship: transforms_into CCO:B0013184 ! NIPBL_HUMAN-Phosphothreonine646 relationship: transforms_into CCO:B0013185 ! NIPBL_HUMAN-Phosphothreonine746 relationship: transforms_into CCO:B0013186 ! NIPBL_HUMAN-Phosphoserine849 relationship: transforms_into CCO:B0013187 ! NIPBL_HUMAN-Phosphoserine850 relationship: transforms_into CCO:B0013188 ! NIPBL_HUMAN-Phosphoserine912 relationship: transforms_into CCO:B0013189 ! NIPBL_HUMAN-Phosphothreonine914 relationship: transforms_into CCO:B0013190 ! NIPBL_HUMAN-Phosphoserine1089 relationship: transforms_into CCO:B0013191 ! NIPBL_HUMAN-Phosphoserine1090 relationship: transforms_into CCO:B0013192 ! NIPBL_HUMAN-Phosphoserine1096 relationship: transforms_into CCO:B0013193 ! NIPBL_HUMAN-Phosphoserine1150 relationship: transforms_into CCO:B0013194 ! NIPBL_HUMAN-Phosphoserine1152 relationship: transforms_into CCO:B0013195 ! NIPBL_HUMAN-Phosphoserine1154 relationship: transforms_into CCO:B0013196 ! NIPBL_HUMAN-Phosphotyrosine1159 relationship: transforms_into CCO:B0013197 ! NIPBL_HUMAN-Phosphoserine2658 relationship: transforms_into CCO:B0013198 ! NIPBL_HUMAN-Phosphothreonine2667 relationship: transforms_into CCO:B0013199 ! NIPBL_HUMAN-Phosphoserine2672 relationship: transforms_into CCO:B0068728 ! NIPBL_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0068729 ! NIPBL_HUMAN-Phosphoserine150 relationship: transforms_into CCO:B0068730 ! NIPBL_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0068731 ! NIPBL_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0068732 ! NIPBL_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0068733 ! NIPBL_HUMAN-Phosphoserine1160 relationship: transforms_into CCO:B0068734 ! NIPBL_HUMAN-Phosphoserine2509 relationship: transforms_into CCO:B0068735 ! NIPBL_HUMAN-Phosphoserine2511 relationship: transforms_into CCO:B0068736 ! NIPBL_HUMAN-Phosphoserine2513 relationship: transforms_into CCO:B0068737 ! NIPBL_HUMAN-Phosphoserine2515 [Term] id: CCO:B0001909 name: RINT1_HUMAN def: "RAD50-interacting protein 1" [UniProtKB:Q6NUQ1] synonym: "HsRINT-1" EXACT [UniProtKB:Q6NUQ1] synonym: "Protein RINT-1" EXACT [UniProtKB:Q6NUQ1] synonym: "RAD50 interactor 1" EXACT [UniProtKB:Q6NUQ1] xref: EMBL:AAG42101.1 xref: EMBL:AAH07120.2 xref: EMBL:AAH68483.1 xref: EMBL:AAQ96849.1 xref: EMBL:AAQ96850.1 xref: EMBL:BAB13910.1 xref: UniProtKB:Q6NUQ1 xref: UniProtKB:Q75MG9 xref: UniProtKB:Q75MH0 xref: UniProtKB:Q96IW8 xref: UniProtKB:Q9H229 xref: UniProtKB:Q9HAD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005491 ! RINT1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007675 ! gfi1b-rint1 physical interaction relationship: participates_in CCO:I0007819 ! zw10_zwilch_1 physical interaction relationship: participates_in CCO:I0008498 ! rint1-bnip3l physical interaction relationship: participates_in CCO:I0008499 ! rint1-sptbn1 physical interaction relationship: participates_in CCO:I0008500 ! rint1-xpnpep1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000185 ! G2/M transition DNA damage checkpoint [Term] id: CCO:B0001910 name: Q6NVV2_HUMAN def: "Septin" [UniProtKB:Q6NVV2] xref: EMBL:AAH67889.1 xref: UniProtKB:Q6NVV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006009 ! LOC441601_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001911 name: CDC73_HUMAN def: "Parafibromin" [UniProtKB:Q6P1J9] synonym: "Cell division cycle protein 73 homolog" EXACT [UniProtKB:Q6P1J9] synonym: "Hyperparathyroidism 2 protein" EXACT [UniProtKB:Q6P1J9] xref: EMBL:AAG45339.1 xref: EMBL:AAH07325.1 xref: EMBL:AAH14351.2 xref: EMBL:AAH65037.1 xref: EMBL:BAB15608.1 xref: EMBL:CAH71049.1 xref: EMBL:CAH71589.1 xref: EMBL:EAW91250.1 xref: UniProtKB:A6NLZ8 xref: UniProtKB:Q6P1J9 xref: UniProtKB:Q6PK51 xref: UniProtKB:Q96A07 xref: UniProtKB:Q9H245 xref: UniProtKB:Q9H5L7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004293 ! CDC73_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006890 ! cdc73-ctnnb1-4 physical interaction relationship: participates_in CCO:I0006999 ! cdc73-ctnnb1 physical interaction relationship: participates_in CCO:I0007000 ! cdc73-tcf4 physical interaction relationship: participates_in CCO:I0007414 ! cdc73-ctnnb1-1 physical interaction relationship: participates_in CCO:I0007415 ! cdc73-ctnnb1-2 physical interaction relationship: participates_in CCO:I0007416 ! cdc73-ctnnb1-5 physical interaction relationship: participates_in CCO:I0007790 ! cdc73-ctnnb1-3 physical interaction relationship: participates_in CCO:I0007791 ! cdc73-ctnnb1-6 physical interaction relationship: participates_in CCO:I0007792 ! cdc73-ctnnb1-7 physical interaction relationship: participates_in CCO:I0007917 ! parafibromin-ctnnb1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0064199 ! CDC73_HUMAN-Phosphoserine212 [Term] id: CCO:B0001912 name: PMF1_HUMAN def: "Polyamine-modulated factor 1" [UniProtKB:Q6P1K2] synonym: "PMF-1" EXACT [UniProtKB:Q6P1K2] xref: EMBL:AAD50080.1 xref: EMBL:AAD50081.1 xref: EMBL:AAH33656.2 xref: EMBL:AAH50735.1 xref: EMBL:AAH56417.1 xref: EMBL:AAH65031.1 xref: EMBL:CAH10730.1 xref: EMBL:CAI15536.1 xref: EMBL:CAI15539.1 xref: EMBL:CAI15540.1 xref: UniProtKB:Q5TCJ8 xref: UniProtKB:Q5TCJ9 xref: UniProtKB:Q5TCK3 xref: UniProtKB:Q69YZ9 xref: UniProtKB:Q6P1K2 xref: UniProtKB:Q6PHR4 xref: UniProtKB:Q86VJ6 xref: UniProtKB:Q8N4T6 xref: UniProtKB:Q9UBQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005343 ! PMF1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000092 ! MIS12/MIND type complex relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: participates_in CCO:I0008149 ! pmf1-cops6 physical interaction relationship: participates_in CCO:I0008150 ! pmf1-git1 physical interaction relationship: participates_in CCO:I0008291 ! pmf1-med31 physical interaction relationship: participates_in CCO:I0008292 ! pmf1-crmp1 physical interaction relationship: participates_in CCO:I0008293 ! pmf1-ptn physical interaction relationship: participates_in CCO:I0008419 ! pmf1-gdf9 physical interaction relationship: participates_in CCO:I0008420 ! pmf1-kiaa1377 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001913 name: L2GL2_HUMAN def: "Lethal(2) giant larvae protein homolog 2" [UniProtKB:Q6P1M3] synonym: "HGL" EXACT [UniProtKB:Q6P1M3] xref: EMBL:AAH06503.1 xref: EMBL:AAH10879.1 xref: EMBL:AAH64994.1 xref: EMBL:CAA60780.1 xref: UniProtKB:Q14521 xref: UniProtKB:Q6P1M3 xref: UniProtKB:Q9BR62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004967 ! LLGL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012657 ! L2GL2_HUMAN-Phosphoserine664 relationship: transforms_into CCO:B0067517 ! L2GL2_HUMAN-Phosphoserine1015 [Term] id: CCO:B0001914 name: BORA_HUMAN def: "Protein aurora borealis" [UniProtKB:Q6PGQ7] synonym: "HsBora" EXACT [UniProtKB:Q6PGQ7] xref: EMBL:AAH07119.1 xref: EMBL:AAH25367.2 xref: EMBL:AAH44213.1 xref: EMBL:AAH56876.2 xref: EMBL:BAB15426.1 xref: EMBL:CAH72712.2 xref: EMBL:CAH72713.1 xref: UniProtKB:Q5W0P3 xref: UniProtKB:Q5W0P4 xref: UniProtKB:Q6PGQ7 xref: UniProtKB:Q86YC6 xref: UniProtKB:Q96IW9 xref: UniProtKB:Q9H640 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004181 ! BORA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008387 ! fgfr3-flj22624 physical interaction relationship: participates_in CCO:I0008389 ! flj22624-fez1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0063947 ! BORA_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0063948 ! BORA_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0063949 ! BORA_HUMAN-Phosphoserine191 [Term] id: CCO:B0001915 name: SYCE2_HUMAN def: "Synaptonemal complex central element protein 2" [UniProtKB:Q6PIF2] synonym: "Central element synaptonemal complex protein 1" EXACT [UniProtKB:Q6PIF2] xref: EMBL:AAH35819.1 xref: UniProtKB:Q6PIF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005709 ! SYCE2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000128 ! central element relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000119 ! meiotic prophase I relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001916 name: DCR1A_HUMAN def: "DNA cross-link repair 1A protein" [UniProtKB:Q6PJP8] synonym: "hSNM1" EXACT [UniProtKB:Q6PJP8] synonym: "hSNM1A" EXACT [UniProtKB:Q6PJP8] xref: EMBL:AAH13124.1 xref: EMBL:AAH62582.1 xref: EMBL:AAT09762.1 xref: EMBL:BAA07646.2 xref: EMBL:CAI12637.1 xref: UniProtKB:Q14701 xref: UniProtKB:Q6P5Y3 xref: UniProtKB:Q6PJP8 xref: UniProtKB:Q6PKL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004446 ! DCLRE1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011451 ! DCR1A_HUMAN-Phosphoserine590 [Term] id: CCO:B0001917 name: Q6Q9Z6_HUMAN def: "E2F6 splice variant b" [UniProtKB:Q6Q9Z6] xref: EMBL:AAT02637.1 xref: UniProtKB:Q6Q9Z6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004538 ! E2F6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001918 name: SAS6_HUMAN def: "Spindle assembly abnormal protein 6 homolog" [UniProtKB:Q6UVJ0] synonym: "HsSAS-6" EXACT [UniProtKB:Q6UVJ0] xref: EMBL:AAQ57128.1 xref: EMBL:CAD38940.1 xref: EMBL:CAH72248.1 xref: UniProtKB:Q6UVJ0 xref: UniProtKB:Q8N3K0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005564 ! SASS6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000300 ! centrosome duplication relationship: transforms_into CCO:B0070320 ! SAS6_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0070321 ! SAS6_HUMAN-Phosphoserine657 [Term] id: CCO:B0001919 name: RAD9B_HUMAN def: "Cell cycle checkpoint control protein RAD9B homolog" [UniProtKB:Q6WBX8] synonym: "hRAD9B" EXACT [UniProtKB:Q6WBX8] synonym: "RAD9 homolog B" EXACT [UniProtKB:Q6WBX8] xref: EMBL:AAH47645.1 xref: EMBL:AAH68031.2 xref: EMBL:AAQ62859.1 xref: EMBL:BAB71704.1 xref: EMBL:BAC05138.1 xref: EMBL:BAC85774.1 xref: UniProtKB:Q5U5K0 xref: UniProtKB:Q6NVJ1 xref: UniProtKB:Q6WBX8 xref: UniProtKB:Q6ZVT7 xref: UniProtKB:Q8N7T9 xref: UniProtKB:Q96LI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005420 ! RAD9B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0001920 name: Q6WZM0_HUMAN def: "Vascular endothelial growth factor A splice variant VEGF 117" [UniProtKB:Q6WZM0] xref: EMBL:AAP86646.1 xref: UniProtKB:Q6WZM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005897 ! VEGF_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001922 name: TM11A_HUMAN def: "Transmembrane protease, serine 11A" [UniProtKB:Q6ZMR5] synonym: "Airway trypsin-like protease 1" EXACT [UniProtKB:Q6ZMR5] synonym: "EC 3.4.21.-" EXACT [UniProtKB:Q6ZMR5] synonym: "Epidermal type-II transmembrane serine protease" EXACT [UniProtKB:Q6ZMR5] synonym: "Esophageal cancer-susceptibility gene 1 protein" EXACT [UniProtKB:Q6ZMR5] xref: EMBL:AAD41463.1 xref: EMBL:AAI11797.1 xref: EMBL:AAS78642.1 xref: EMBL:BAD18660.1 xref: EMBL:CAD67985.1 xref: UniProtKB:Q2NKI9 xref: UniProtKB:Q6JE90 xref: UniProtKB:Q6ZMR5 xref: UniProtKB:Q7RTY4 xref: UniProtKB:Q86TK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005793 ! TMPRSS11A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001923 name: Q6ZNA8_HUMAN def: "cDNA FLJ16262 fis, clone IMR322008651, highly similar to DNA REPAIR PROTEIN RAD51" [UniProtKB:Q6ZNA8] synonym: "cDNA FLJ78599" EXACT [UniProtKB:Q6ZNA8] synonym: "RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae), isoform CRA_e" EXACT [UniProtKB:Q6ZNA8] xref: EMBL:BAD18467.1 xref: EMBL:BAF84658.1 xref: EMBL:EAW92435.1 xref: UniProtKB:Q6ZNA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005416 ! RAD51_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000632 ! DNA unwinding during replication [Term] id: CCO:B0001924 name: Q6ZQZ4_HUMAN def: "cDNA FLJ46776 fis, clone TRACH3026650, highly similar to Actin cross-linking family protein 7" [UniProtKB:Q6ZQZ4] xref: EMBL:BAC87532.1 xref: UniProtKB:Q6ZQZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001925 name: SEP14_HUMAN def: "Septin-14" [UniProtKB:Q6ZU15] xref: EMBL:BAC86412.1 xref: UniProtKB:Q6ZU15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005583 ! SEPT14_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001926 name: Q6ZV00_HUMAN def: "cDNA FLJ43165 fis, clone FCBBF3002163, highly similar to Homo sapiens chromosome condensation-related SMC-associated protein 1" [UniProtKB:Q6ZV00] xref: EMBL:BAC86066.1 xref: UniProtKB:Q6ZV00 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001927 name: Q70WG0_HUMAN def: "T-cell-specific surface glycoprotein" [UniProtKB:Q70WG0] synonym: "CD28 antigen (Tp44), isoform CRA_b" EXACT [UniProtKB:Q70WG0] xref: EMBL:CAD57003.1 xref: EMBL:EAW70348.1 xref: UniProtKB:Q70WG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004270 ! CD28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process [Term] id: CCO:B0001928 name: ERN2_HUMAN def: "Serine/threonine-protein kinase/endoribonuclease IRE2 precursor" [UniProtKB:Q76MJ5] synonym: "Endoplasmic reticulum-to-nucleus signaling 2" EXACT [UniProtKB:Q76MJ5] synonym: "hIRE2p" EXACT [UniProtKB:Q76MJ5] synonym: "Inositol-requiring protein 2" EXACT [UniProtKB:Q76MJ5] synonym: "Ire1-beta" EXACT [UniProtKB:Q76MJ5] synonym: "IRE1b" EXACT [UniProtKB:Q76MJ5] xref: EMBL:BAB21297.1 xref: EMBL:BAD18455.1 xref: UniProtKB:Q6ZNC0 xref: UniProtKB:Q76MJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004586 ! ERN2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0001929 name: MCM10_HUMAN def: "Protein MCM10 homolog" [UniProtKB:Q7L590] synonym: "HsMCM10" EXACT [UniProtKB:Q7L590] xref: EMBL:AAF69623.1 xref: EMBL:AAH04876.2 xref: EMBL:AAI01728.1 xref: EMBL:BAB18723.1 xref: EMBL:BAB70988.1 xref: EMBL:CAB66774.2 xref: EMBL:CAI12913.1 xref: EMBL:CAI16558.1 xref: UniProtKB:Q3MIR3 xref: UniProtKB:Q7L590 xref: UniProtKB:Q7LD55 xref: UniProtKB:Q96GX4 xref: UniProtKB:Q96NB6 xref: UniProtKB:Q9H0D7 xref: UniProtKB:Q9H3P9 xref: UniProtKB:Q9P177 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005036 ! MCM10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006082 ! mcm10-orc4l direct interaction relationship: participates_in CCO:I0006083 ! mcm10-mcm2 direct interaction relationship: participates_in CCO:I0006085 ! mcm10-mcm6 direct interaction relationship: participates_in CCO:I0006087 ! mcm10-orc2l direct interaction relationship: participates_in CCO:I0006092 ! mcm10-cdc7 direct interaction relationship: participates_in CCO:I0006095 ! mcm10-mcm3 direct interaction relationship: participates_in CCO:I0006098 ! mcm10-ccnd3 direct interaction relationship: participates_in CCO:I0006101 ! mcm10-hscdc5 direct interaction relationship: participates_in CCO:I0006104 ! mcm10-hscdc6 direct interaction relationship: participates_in CCO:I0006105 ! mcm10-ccnd1 direct interaction relationship: participates_in CCO:I0006106 ! mcm10-mcm7 direct interaction relationship: participates_in CCO:I0006119 ! mcm10-cdk6 direct interaction relationship: participates_in CCO:I0006125 ! orc3l-mcm10 direct interaction relationship: participates_in CCO:I0006145 ! cdkn2a-mcm10 direct interaction relationship: participates_in CCO:I0006161 ! cdkn1a-mcm10 direct interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0012803 ! MCM10_HUMAN-Phosphothreonine85 relationship: transforms_into CCO:B0012804 ! MCM10_HUMAN-Phosphoserine93 [Term] id: CCO:B0001930 name: MAEA_HUMAN def: "Macrophage erythroblast attacher" [UniProtKB:Q7L5Y9] synonym: "Cell proliferation-inducing gene 5 protein" EXACT [UniProtKB:Q7L5Y9] synonym: "Erythroblast macrophage protein" EXACT [UniProtKB:Q7L5Y9] synonym: "HLC-10" EXACT [UniProtKB:Q7L5Y9] synonym: "Lung cancer-related protein 10" EXACT [UniProtKB:Q7L5Y9] xref: EMBL:AAC67543.1 xref: EMBL:AAH01225.2 xref: EMBL:AAH06470.1 xref: EMBL:AAO85220.1 xref: EMBL:AAP35603.1 xref: EMBL:AAP74806.1 xref: EMBL:BAA91499.1 xref: EMBL:BAB14072.1 xref: EMBL:BAB14113.1 xref: EMBL:BAC87375.1 xref: UniProtKB:O95285 xref: UniProtKB:Q5JB54 xref: UniProtKB:Q6ZRD6 xref: UniProtKB:Q7L5Y9 xref: UniProtKB:Q9BQ11 xref: UniProtKB:Q9H9V6 xref: UniProtKB:Q9H9Z4 xref: UniProtKB:Q9NW84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005014 ! MAEA_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000394 ! contractile ring relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000138 ! regulation of mitotic cell cycle relationship: participates_in CCO:P0001763 ! negative regulation of myeloid cell apoptosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001931 name: VASH1_HUMAN def: "Vasohibin-1" [UniProtKB:Q7L8A9] xref: EMBL:AAD44361.1 xref: EMBL:AAF02829.1 xref: EMBL:AAH09031.1 xref: EMBL:AAH51896.1 xref: EMBL:BAA82988.2 xref: EMBL:CAD89941.1 xref: UniProtKB:Q7L8A9 xref: UniProtKB:Q96H02 xref: UniProtKB:Q9UBF4 xref: UniProtKB:Q9Y629 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005893 ! VASH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001932 name: STRAD_HUMAN def: "STE20-related adapter protein" [UniProtKB:Q7RTN6] synonym: "Serologically defined breast cancer antigen NY-BR-96" EXACT [UniProtKB:Q7RTN6] synonym: "STRAD alpha" EXACT [UniProtKB:Q7RTN6] xref: EMBL:AAG48269.1 xref: EMBL:AAP42280.1 xref: EMBL:BAC11197.1 xref: EMBL:BAC11349.1 xref: EMBL:DAA01797.1 xref: UniProtKB:Q7RTN6 xref: UniProtKB:Q7Z4K9 xref: UniProtKB:Q8NC31 xref: UniProtKB:Q8NCF1 xref: UniProtKB:Q9H272 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005697 ! STRAD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006454 ! lkb1-strad-2 physical interaction relationship: participates_in CCO:I0006455 ! lkb1-strad-4 physical interaction relationship: participates_in CCO:I0006456 ! stk11-strad-5 physical interaction relationship: participates_in CCO:I0006778 ! lkb1-strad-7 phosphorylation relationship: participates_in CCO:I0006779 ! lkb1-strad-8 phosphorylation relationship: participates_in CCO:I0006927 ! stk11-strad-6 colocalization relationship: participates_in CCO:I0007474 ! lkb1-strad-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0014266 ! STRAD_HUMAN-Phosphothreonine329 relationship: transforms_into CCO:B0014267 ! STRAD_HUMAN-Phosphothreonine419 [Term] id: CCO:B0001933 name: CLAP1_HUMAN def: "CLIP-associating protein 1" [UniProtKB:Q7Z460] synonym: "Cytoplasmic linker-associated protein 1" EXACT [UniProtKB:Q7Z460] synonym: "hOrbit1" EXACT [UniProtKB:Q7Z460] synonym: "Multiple asters homolog 1" EXACT [UniProtKB:Q7Z460] xref: EMBL:AAH32563.1 xref: EMBL:AAI12941.1 xref: EMBL:AAQ15051.1 xref: EMBL:AAX88872.1 xref: EMBL:BAA31597.1 xref: EMBL:CAC35156.1 xref: EMBL:CAI46251.1 xref: UniProtKB:O75118 xref: UniProtKB:Q2KHQ9 xref: UniProtKB:Q5H9P0 xref: UniProtKB:Q7Z460 xref: UniProtKB:Q8N5B8 xref: UniProtKB:Q9BQT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004366 ! CLASP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000152 ! exit from mitosis relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0001381 ! negative regulation of microtubule polymerization or depolymerization relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011244 ! CLAP1_HUMAN-Phosphoserine545 relationship: transforms_into CCO:B0011245 ! CLAP1_HUMAN-Phosphoserine559 relationship: transforms_into CCO:B0011246 ! CLAP1_HUMAN-Phosphoserine568 relationship: transforms_into CCO:B0011247 ! CLAP1_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0011248 ! CLAP1_HUMAN-Phosphoserine600 relationship: transforms_into CCO:B0011249 ! CLAP1_HUMAN-Phosphoserine609 relationship: transforms_into CCO:B0011250 ! CLAP1_HUMAN-Phosphoserine1196 relationship: transforms_into CCO:B0011251 ! CLAP1_HUMAN-Phosphoserine1223 relationship: transforms_into CCO:B0048201 ! CLAP1_HUMAN-Phosphoserine646 relationship: transforms_into CCO:B0048202 ! CLAP1_HUMAN-Phosphoserine1091 relationship: transforms_into CCO:B0048203 ! CLAP1_HUMAN-Phosphothreonine1099 relationship: transforms_into CCO:B0064370 ! CLAP1_HUMAN-Phosphoserine647 relationship: transforms_into CCO:B0064371 ! CLAP1_HUMAN-Phosphoserine649 relationship: transforms_into CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: transforms_into CCO:B0064373 ! CLAP1_HUMAN-Phosphoserine688 relationship: transforms_into CCO:B0064374 ! CLAP1_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0064375 ! CLAP1_HUMAN-Phosphothreonine711 relationship: transforms_into CCO:B0064376 ! CLAP1_HUMAN-Phosphoserine714 [Term] id: CCO:B0001935 name: Q7Z774_HUMAN def: "CCNE2 protein" [UniProtKB:Q7Z774] xref: EMBL:AAH07015.1 xref: UniProtKB:Q7Z774 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004252 ! CCNE2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001936 name: NPM2_HUMAN def: "Nucleoplasmin-2" [UniProtKB:Q86SE8] xref: EMBL:AAP33134.1 xref: EMBL:AAP33135.1 xref: UniProtKB:Q86SE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005211 ! NPM2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000116 ! cytoplasmic chromatin relationship: located_in CCO:C0000117 ! nuclear chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: participates_in CCO:P0000249 ! positive regulation of meiosis [Term] id: CCO:B0001938 name: PB1_HUMAN def: "Protein polybromo-1" [UniProtKB:Q86U86] synonym: "BAF180" EXACT [UniProtKB:Q86U86] synonym: "BRG1-associated factor 180" EXACT [UniProtKB:Q86U86] synonym: "hPB1" EXACT [UniProtKB:Q86U86] synonym: "Polybromo-1D" EXACT [UniProtKB:Q86U86] xref: EMBL:AAG34760.1 xref: EMBL:AAG48933.1 xref: EMBL:AAG48939.1 xref: EMBL:AAG48940.1 xref: EMBL:AAG48941.1 xref: EMBL:AAI15010.1 xref: EMBL:AAI15011.1 xref: EMBL:AAI15012.1 xref: EMBL:AAI29935.1 xref: EMBL:AAI29936.1 xref: EMBL:AAP34197.1 xref: EMBL:BAB71210.1 xref: UniProtKB:A1L381 xref: UniProtKB:A1L382 xref: UniProtKB:A4FUJ7 xref: UniProtKB:Q1RMD1 xref: UniProtKB:Q1RMD2 xref: UniProtKB:Q86U86 xref: UniProtKB:Q96MS2 xref: UniProtKB:Q9H2T3 xref: UniProtKB:Q9H2T4 xref: UniProtKB:Q9H2T5 xref: UniProtKB:Q9H301 xref: UniProtKB:Q9H314 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005272 ! PBRM1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0006322 ! pb1-arid2-4 physical interaction relationship: participates_in CCO:I0006729 ! pb1-arid2-2 physical interaction relationship: participates_in CCO:I0006977 ! smarca4-pb1-arid2-2 physical interaction relationship: participates_in CCO:I0007259 ! arid2-pb1-1 physical interaction relationship: participates_in CCO:I0007356 ! pb1-arid2-3 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007961 ! pb1-arid2-1 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013425 ! PB1_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0013426 ! PB1_HUMAN-Phosphotyrosine54 relationship: transforms_into CCO:B0013427 ! PB1_HUMAN-Phosphothreonine301 relationship: transforms_into CCO:B0013428 ! PB1_HUMAN-Phosphoserine636 relationship: transforms_into CCO:B0013429 ! PB1_HUMAN-Phosphoserine948 relationship: transforms_into CCO:B0013430 ! PB1_HUMAN-Phosphoserine1453 relationship: transforms_into CCO:B0048354 ! PB1_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0069137 ! PB1_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0069138 ! PB1_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0069139 ! PB1_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0069140 ! PB1_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0069141 ! PB1_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0069142 ! PB1_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0069143 ! PB1_HUMAN-Phosphoserine1405 [Term] id: CCO:B0001939 name: TLK2_HUMAN def: "Serine/threonine-protein kinase tousled-like 2" [UniProtKB:Q86UE8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q86UE8] synonym: "PKU-alpha" EXACT [UniProtKB:Q86UE8] synonym: "Tousled-like kinase 2" EXACT [UniProtKB:Q86UE8] xref: EMBL:AAF03095.1 xref: EMBL:AAH44925.2 xref: EMBL:BAA20561.1 xref: UniProtKB:Q86UE8 xref: UniProtKB:Q9UKI7 xref: UniProtKB:Q9Y4F7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005792 ! TLK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000469 ! regulation of chromatin assembly or disassembly relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0014413 ! TLK2_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0014414 ! TLK2_HUMAN-Phosphoserine750 [Term] id: CCO:B0001940 name: CUZD1_HUMAN def: "CUB and zona pellucida-like domain-containing protein 1 precursor" [UniProtKB:Q86UP6] synonym: "CUB and ZP domain-containing protein 1" EXACT [UniProtKB:Q86UP6] synonym: "Transmembrane protein UO-44" EXACT [UniProtKB:Q86UP6] xref: EMBL:AAG23215.1 xref: EMBL:AAP15458.1 xref: EMBL:AAP15459.1 xref: EMBL:AAP15460.1 xref: EMBL:AAP15461.1 xref: EMBL:AAQ88920.1 xref: EMBL:CAD98079.2 xref: EMBL:CAD98080.2 xref: EMBL:CAH70003.1 xref: EMBL:CAH70004.1 xref: EMBL:CAH70006.1 xref: UniProtKB:Q7Z660 xref: UniProtKB:Q7Z661 xref: UniProtKB:Q86SG1 xref: UniProtKB:Q86UP5 xref: UniProtKB:Q86UP6 xref: UniProtKB:Q9HAR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004429 ! CUZD1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001661 ! zymogen granule membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001941 name: NIPA_HUMAN def: "Nuclear-interacting partner of ALK" [UniProtKB:Q86WB0] synonym: "hNIPA" EXACT [UniProtKB:Q86WB0] synonym: "Nuclear-interacting partner of anaplastic lymphoma kinase" EXACT [UniProtKB:Q86WB0] synonym: "Zinc finger C3HC-type protein 1" EXACT [UniProtKB:Q86WB0] xref: EMBL:AAF36136.1 xref: EMBL:AAH11551.1 xref: EMBL:AAH28917.1 xref: EMBL:AAS07546.1 xref: EMBL:AAS07547.1 xref: EMBL:BAA91619.1 xref: EMBL:BAB14024.1 xref: EMBL:CAD61161.1 xref: UniProtKB:A6NH66 xref: UniProtKB:Q75MF3 xref: UniProtKB:Q75MF4 xref: UniProtKB:Q86WB0 xref: UniProtKB:Q8N330 xref: UniProtKB:Q96F75 xref: UniProtKB:Q9HA34 xref: UniProtKB:Q9NVX4 xref: UniProtKB:Q9P0R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005195 ! ZC3HC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013174 ! NIPA_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0013175 ! NIPA_HUMAN-Phosphothreonine28 relationship: transforms_into CCO:B0013176 ! NIPA_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0013177 ! NIPA_HUMAN-Phosphoserine321 relationship: transforms_into CCO:B0013178 ! NIPA_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0013179 ! NIPA_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0036019 ! NIPA_HUMAN-Phosphothreonine84 relationship: transforms_into CCO:B0048337 ! NIPA_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0068720 ! NIPA_HUMAN-Phosphothreonine333 relationship: transforms_into CCO:B0068721 ! NIPA_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0068722 ! NIPA_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0068723 ! NIPA_HUMAN-Phosphoserine344 relationship: transforms_into CCO:B0068724 ! NIPA_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0068725 ! NIPA_HUMAN-Phosphothreonine384 relationship: transforms_into CCO:B0068726 ! NIPA_HUMAN-Phosphothreonine387 relationship: transforms_into CCO:B0068727 ! NIPA_HUMAN-Phosphoserine394 [Term] id: CCO:B0001942 name: HORM1_HUMAN def: "HORMA domain-containing protein 1" [UniProtKB:Q86X24] synonym: "Cancer/testis antigen 46" EXACT [UniProtKB:Q86X24] synonym: "CT46" EXACT [UniProtKB:Q86X24] synonym: "Newborn ovary HORMA protein" EXACT [UniProtKB:Q86X24] xref: EMBL:AAH33014.1 xref: EMBL:AAH47406.1 xref: EMBL:AAT45740.1 xref: EMBL:CAB66689.1 xref: EMBL:CAG38536.1 xref: EMBL:CAI13652.1 xref: EMBL:CAI13653.1 xref: EMBL:CAI13654.1 xref: EMBL:CAI13655.1 xref: EMBL:CAI13656.1 xref: UniProtKB:Q4G114 xref: UniProtKB:Q5T5I3 xref: UniProtKB:Q5T5I4 xref: UniProtKB:Q5T5I5 xref: UniProtKB:Q6FIC1 xref: UniProtKB:Q86X24 xref: UniProtKB:Q9H0K8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004824 ! HORMAD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001943 name: CNDG2_HUMAN def: "Condensin-2 complex subunit G2" [UniProtKB:Q86XI2] synonym: "CAP-G2" EXACT [UniProtKB:Q86XI2] synonym: "Chromosome-associated protein G2" EXACT [UniProtKB:Q86XI2] synonym: "hCAP-G2" EXACT [UniProtKB:Q86XI2] synonym: "Leucine zipper protein 5" EXACT [UniProtKB:Q86XI2] synonym: "Non-SMC condensin II complex subunit G2" EXACT [UniProtKB:Q86XI2] xref: EMBL:AAH05878.2 xref: EMBL:AAH20560.1 xref: EMBL:AAH43404.1 xref: EMBL:BAB14219.1 xref: EMBL:BAB14534.1 xref: EMBL:CAD97854.1 xref: UniProtKB:Q7Z3J9 xref: UniProtKB:Q86XI2 xref: UniProtKB:Q8WUG8 xref: UniProtKB:Q9BRX6 xref: UniProtKB:Q9H8S2 xref: UniProtKB:Q9H9K6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004380 ! NCAPG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011317 ! CNDG2_HUMAN-Phosphothreonine805 relationship: transforms_into CCO:B0011318 ! CNDG2_HUMAN-Phosphothreonine1119 [Term] id: CCO:B0001944 name: GA2L3_HUMAN def: "GAS2-like protein 3" [UniProtKB:Q86XJ1] synonym: "Growth arrest-specific protein 2-like 3" EXACT [UniProtKB:Q86XJ1] xref: EMBL:AAH43366.1 xref: UniProtKB:Q86XJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004673 ! GAS2L3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0066352 ! GA2L3_HUMAN-Phosphoserine438 relationship: transforms_into CCO:B0066353 ! GA2L3_HUMAN-Phosphothreonine441 relationship: transforms_into CCO:B0066354 ! GA2L3_HUMAN-Phosphoserine570 [Term] id: CCO:B0001946 name: SIAH1_HUMAN def: "E3 ubiquitin-protein ligase SIAH1" [UniProtKB:Q8IUQ4] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8IUQ4] synonym: "Seven in absentia homolog 1" EXACT [UniProtKB:Q8IUQ4] synonym: "Siah-1" EXACT [UniProtKB:Q8IUQ4] synonym: "Siah-1a" EXACT [UniProtKB:Q8IUQ4] xref: EMBL:AAC12950.1 xref: EMBL:AAC51907.1 xref: EMBL:AAH35562.1 xref: EMBL:AAH42550.1 xref: EMBL:AAH44920.1 xref: EMBL:ABK15529.1 xref: EMBL:CAC35542.1 xref: EMBL:CAE46191.1 xref: UniProtKB:A0FKF3 xref: UniProtKB:O43269 xref: UniProtKB:Q49A58 xref: UniProtKB:Q8IUQ4 xref: UniProtKB:Q92880 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005612 ! SIAH1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005805 ! aff4-siah1 physical interaction relationship: participates_in CCO:I0005945 ! khdrbs3-siah1 physical interaction relationship: participates_in CCO:I0007616 ! atn1-siah1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001947 name: EGFL6_HUMAN def: "EGF-like domain-containing protein 6 precursor" [UniProtKB:Q8IUX8] synonym: "MAM and EGF domains-containing gene protein" EXACT [UniProtKB:Q8IUX8] synonym: "Multiple EGF-like domain protein 6" EXACT [UniProtKB:Q8IUX8] synonym: "Multiple epidermal growth factor-like domain protein 6" EXACT [UniProtKB:Q8IUX8] xref: EMBL:AAF27812.1 xref: EMBL:AAG22483.1 xref: EMBL:AAH38587.1 xref: EMBL:AAQ88699.1 xref: EMBL:BAC11477.1 xref: EMBL:CAB56014.2 xref: EMBL:CAB92132.1 xref: UniProtKB:Q6UXJ1 xref: UniProtKB:Q8IUX8 xref: UniProtKB:Q8NBV0 xref: UniProtKB:Q8WYG3 xref: UniProtKB:Q9NY67 xref: UniProtKB:Q9NZL7 xref: UniProtKB:Q9UFK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004550 ! EGFL6_human relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008225 ! egfl6-sh3gl3 physical interaction relationship: participates_in CCO:I0008385 ! egfl6-sh3gl2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001949 name: PARC_HUMAN def: "p53-associated parkin-like cytoplasmic protein" [UniProtKB:Q8IWT3] synonym: "UbcH7-associated protein 1" EXACT [UniProtKB:Q8IWT3] xref: EMBL:AAH02879.2 xref: EMBL:AAN61516.1 xref: EMBL:BAA31683.3 xref: EMBL:BAC85207.1 xref: EMBL:BAC86090.1 xref: EMBL:CAC85756.1 xref: EMBL:CAH18328.1 xref: EMBL:CAH18696.1 xref: UniProtKB:O75188 xref: UniProtKB:Q68CP2 xref: UniProtKB:Q68D92 xref: UniProtKB:Q8IWT3 xref: UniProtKB:Q8N3W9 xref: UniProtKB:Q9BU56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005265 ! PARC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: participates_in CCO:I0006475 ! kiaa1206-parc physical interaction relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition [Term] id: CCO:B0001950 name: CCAR1_HUMAN def: "Cell division cycle and apoptosis regulator protein 1" [UniProtKB:Q8IX12] synonym: "CARP-1" EXACT [UniProtKB:Q8IX12] synonym: "Cell cycle and apoptosis regulatory protein 1" EXACT [UniProtKB:Q8IX12] synonym: "Death inducer with SAP domain" EXACT [UniProtKB:Q8IX12] xref: EMBL:AAH26036.1 xref: EMBL:AAI08683.1 xref: EMBL:AAO17319.1 xref: EMBL:AAP82002.1 xref: EMBL:BAA91354.1 xref: EMBL:BAA91700.1 xref: EMBL:BAA91847.1 xref: EMBL:BAB14574.1 xref: EMBL:CAH70221.1 xref: EMBL:CAH73835.1 xref: UniProtKB:Q32NE3 xref: UniProtKB:Q5VUP6 xref: UniProtKB:Q6PIZ0 xref: UniProtKB:Q6X935 xref: UniProtKB:Q8IX12 xref: UniProtKB:Q9H8N4 xref: UniProtKB:Q9NVA7 xref: UniProtKB:Q9NVQ0 xref: UniProtKB:Q9NWM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004236 ! CCAR1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006365 ! ikbkg-q8ix12 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0010974 ! CCAR1_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0010975 ! CCAR1_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0010976 ! CCAR1_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0010977 ! CCAR1_HUMAN-Phosphoserine339 relationship: transforms_into CCO:B0010978 ! CCAR1_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0010979 ! CCAR1_HUMAN-Phosphoserine1149 [Term] id: CCO:B0001951 name: SIRT2_HUMAN def: "NAD-dependent deacetylase sirtuin-2" [UniProtKB:Q8IXJ6] synonym: "EC 3.5.1.-" EXACT [UniProtKB:Q8IXJ6] synonym: "SIR2-like" EXACT [UniProtKB:Q8IXJ6] synonym: "SIR2-like protein 2" EXACT [UniProtKB:Q8IXJ6] xref: EMBL:AAD20046.1 xref: EMBL:AAD40850.2 xref: EMBL:AAD45971.1 xref: EMBL:AAF67015.1 xref: EMBL:AAH03012.1 xref: EMBL:AAH03547.1 xref: EMBL:AAK51133.1 xref: EMBL:CAD43717.1 xref: UniProtKB:O95889 xref: UniProtKB:Q8IXJ6 xref: UniProtKB:Q924Y7 xref: UniProtKB:Q9P0G8 xref: UniProtKB:Q9UNT0 xref: UniProtKB:Q9Y6E9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005617 ! SIRT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006513 ! sirt2-hdac6-2 colocalization relationship: participates_in CCO:I0006708 ! sirt2-hdac6-1 physical interaction relationship: participates_in CCO:I0006958 ! sirt2-pcaf-myod1-2 physical interaction relationship: participates_in CCO:I0007534 ! sirt2-pcaf-1 physical interaction relationship: participates_in CCO:I0007535 ! sirt2-pcaf-2 physical interaction relationship: participates_in CCO:I0007536 ! sirt2-pcaf-myod1-1 physical interaction relationship: participates_in CCO:I0007847 ! sirt2-pcaf-3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: participates_in CCO:P0000408 ! chromatin silencing at rDNA relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000653 ! chromatin silencing at telomere relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001125 ! gene silencing relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041195 ! SIRT2_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0041196 ! SIRT2_HUMAN-Phosphoserine27 [Term] id: CCO:B0001952 name: RM41_HUMAN def: "39S ribosomal protein L41, mitochondrial precursor" [UniProtKB:Q8IXM3] synonym: "39S ribosomal protein L27 homolog" EXACT [UniProtKB:Q8IXM3] synonym: "Bcl-2-interacting mitochondrial ribosomal protein L41" EXACT [UniProtKB:Q8IXM3] synonym: "Cell proliferation-inducing gene 3 protein" EXACT [UniProtKB:Q8IXM3] synonym: "L41mt" EXACT [UniProtKB:Q8IXM3] synonym: "MRP-L27 homolog" EXACT [UniProtKB:Q8IXM3] synonym: "MRP-L41" EXACT [UniProtKB:Q8IXM3] xref: EMBL:AAH40035.1 xref: EMBL:AAP69986.1 xref: EMBL:BAB54952.1 xref: EMBL:CAI14583.1 xref: UniProtKB:Q8IXM3 xref: UniProtKB:Q96Q49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005515 ! MRPL41_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000345 ! mitochondrial large ribosomal subunit relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001954 name: XRN1_HUMAN def: "5'-3' exoribonuclease 1" [UniProtKB:Q8IZH2] synonym: "EC 3.1.11.-" EXACT [UniProtKB:Q8IZH2] synonym: "Strand-exchange protein 1 homolog" EXACT [UniProtKB:Q8IZH2] xref: EMBL:AAH39314.1 xref: EMBL:AAH48104.1 xref: EMBL:AAN11306.1 xref: EMBL:BAC04718.1 xref: EMBL:CAB63749.1 xref: EMBL:CAE45950.1 xref: EMBL:CAH10490.1 xref: EMBL:CAH18332.1 xref: UniProtKB:Q4G0S3 xref: UniProtKB:Q68D88 xref: UniProtKB:Q6AI24 xref: UniProtKB:Q6MZS8 xref: UniProtKB:Q86WS7 xref: UniProtKB:Q8IZH2 xref: UniProtKB:Q8N8U4 xref: UniProtKB:Q9UF39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005947 ! XRN1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001876 ! 5'-3' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006911 ! dcp1a-rcd8-xrn1 colocalization relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0014721 ! XRN1_HUMAN-Phosphoserine1173 relationship: transforms_into CCO:B0014722 ! XRN1_HUMAN-Phosphoserine1176 [Term] id: CCO:B0001955 name: CCRK_HUMAN def: "Cell cycle-related kinase" [UniProtKB:Q8IZL9] synonym: "CAK-kinase p42" EXACT [UniProtKB:Q8IZL9] synonym: "CDK-activating kinase p42" EXACT [UniProtKB:Q8IZL9] synonym: "Cyclin-dependent protein kinase H" EXACT [UniProtKB:Q8IZL9] synonym: "Cyclin-kinase-activating kinase p42" EXACT [UniProtKB:Q8IZL9] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q8IZL9] xref: EMBL:AAH02655.1 xref: EMBL:AAN28684.1 xref: EMBL:AAW82349.1 xref: EMBL:CAH72843.1 xref: UniProtKB:Q5EDC4 xref: UniProtKB:Q5VYW1 xref: UniProtKB:Q8IZL9 xref: UniProtKB:Q9BUF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004266 ! CCRK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001956 name: ASPM_HUMAN def: "Abnormal spindle-like microcephaly-associated protein" [UniProtKB:Q8IZT6] synonym: "Abnormal spindle protein homolog" EXACT [UniProtKB:Q8IZT6] synonym: "Asp homolog" EXACT [UniProtKB:Q8IZT6] xref: EMBL:AAH15396.1 xref: EMBL:AAH34607.1 xref: EMBL:AAM44119.1 xref: EMBL:AAM44120.1 xref: EMBL:AAM44121.1 xref: EMBL:AAM44122.1 xref: EMBL:AAM48745.1 xref: EMBL:AAN40011.1 xref: EMBL:AAR12641.1 xref: EMBL:BAA91660.1 xref: EMBL:BAA91676.1 xref: EMBL:CAH72552.1 xref: EMBL:EAW91274.1 xref: UniProtKB:Q5VYL3 xref: UniProtKB:Q86UX4 xref: UniProtKB:Q8IUL2 xref: UniProtKB:Q8IZJ7 xref: UniProtKB:Q8IZJ8 xref: UniProtKB:Q8IZJ9 xref: UniProtKB:Q8IZT6 xref: UniProtKB:Q8N4D1 xref: UniProtKB:Q9NVS1 xref: UniProtKB:Q9NVT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004108 ! ASPM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010607 ! ASPM_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0010608 ! ASPM_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0010609 ! ASPM_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0010610 ! ASPM_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0010611 ! ASPM_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0010612 ! ASPM_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0010613 ! ASPM_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0010614 ! ASPM_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0010615 ! ASPM_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0010616 ! ASPM_HUMAN-Phosphoserine348 relationship: transforms_into CCO:B0010617 ! ASPM_HUMAN-Phosphoserine367 relationship: transforms_into CCO:B0010618 ! ASPM_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0010619 ! ASPM_HUMAN-Phosphoserine392 relationship: transforms_into CCO:B0010620 ! ASPM_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0010621 ! ASPM_HUMAN-Phosphoserine463 relationship: transforms_into CCO:B0010622 ! ASPM_HUMAN-Phosphothreonine563 relationship: transforms_into CCO:B0010623 ! ASPM_HUMAN-Phosphoserine605 relationship: transforms_into CCO:B0010624 ! ASPM_HUMAN-Phosphothreonine647 relationship: transforms_into CCO:B0010625 ! ASPM_HUMAN-Phosphoserine1103 relationship: transforms_into CCO:B0010626 ! ASPM_HUMAN-Phosphoserine2429 relationship: transforms_into CCO:B0010627 ! ASPM_HUMAN-Phosphothreonine3435 [Term] id: CCO:B0001957 name: SYCP3_HUMAN def: "Synaptonemal complex protein 3" [UniProtKB:Q8IZU3] synonym: "SCP-3" EXACT [UniProtKB:Q8IZU3] xref: EMBL:AAH62662.1 xref: EMBL:AAN06611.1 xref: EMBL:AAP47204.1 xref: UniProtKB:Q8IZU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005712 ! SYCP3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000127 ! lateral element relationship: located_in CCO:C0000129 ! transverse filament relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000043 ! achiasmate meiosis I relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000080 ! female meiosis sister chromatid cohesion relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000121 ! synaptonemal complex assembly relationship: participates_in CCO:P0000132 ! male meiosis I relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001958 name: Q8IZX3_HUMAN def: "MAD2 mitotic arrest deficient-like 1 variant" [UniProtKB:Q8IZX3] synonym: "cDNA FLJ50822, moderately similar to Mitotic spindle assembly checkpoint protein MAD2A" EXACT [UniProtKB:Q8IZX3] synonym: "MAD2 mitotic arrest deficient-like 1 (Yeast), isoform CRA_b" EXACT [UniProtKB:Q8IZX3] xref: EMBL:AAN74648.1 xref: EMBL:BAG60497.1 xref: EMBL:EAX05271.1 xref: UniProtKB:Q8IZX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005048 ! MAD2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001959 name: TAF1L_HUMAN def: "Transcription initiation factor TFIID 210 kDa subunit" [UniProtKB:Q8IZX4] synonym: "TAF(II)210" EXACT [UniProtKB:Q8IZX4] synonym: "TBP-associated factor 1-like" EXACT [UniProtKB:Q8IZX4] synonym: "TBP-associated factor 210 kDa" EXACT [UniProtKB:Q8IZX4] xref: EMBL:AAN40840.1 xref: UniProtKB:Q0VG57 xref: UniProtKB:Q8IZX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005725 ! TAF1L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003518 ! TATA-binding protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:I0007734 ! taf1l-tbp-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000131 ! male meiosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0001960 name: SYCE1_HUMAN def: "Synaptonemal complex central element protein 1" [UniProtKB:Q8N0S2] synonym: "Cancer/testis antigen 76" EXACT [UniProtKB:Q8N0S2] synonym: "CT76" EXACT [UniProtKB:Q8N0S2] xref: EMBL:AAH34821.1 xref: EMBL:AAK14796.1 xref: EMBL:AAK14797.1 xref: EMBL:AAK21976.1 xref: EMBL:CAH70048.1 xref: UniProtKB:Q8N0S2 xref: UniProtKB:Q9BWU3 xref: UniProtKB:Q9BWU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005708 ! SYCE1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000128 ! central element relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000119 ! meiotic prophase I relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001961 name: CNTRB_HUMAN def: "Centrobin" [UniProtKB:Q8N137] synonym: "Centrosomal BRCA2-interacting protein" EXACT [UniProtKB:Q8N137] synonym: "LYST-interacting protein 8" EXACT [UniProtKB:Q8N137] xref: EMBL:AAG49447.1 xref: EMBL:AAH14055.3 xref: EMBL:AAH21134.1 xref: EMBL:AAL56068.2 xref: EMBL:AAO22135.1 xref: EMBL:AAO22136.1 xref: EMBL:BAC11241.1 xref: EMBL:CAD38763.1 xref: EMBL:CAH10698.1 xref: UniProtKB:A6NHQ1 xref: UniProtKB:Q331K3 xref: UniProtKB:Q69YV7 xref: UniProtKB:Q8N137 xref: UniProtKB:Q8NCB8 xref: UniProtKB:Q8WXV3 xref: UniProtKB:Q96CQ7 xref: UniProtKB:Q9C060 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004382 ! CNTROB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007613 ! aptx-cntrob physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000109 ! centriole replication relationship: participates_in CCO:P0000301 ! centrosome separation relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011319 ! CNTRB_HUMAN-Phosphoserine781 [Term] id: CCO:B0001962 name: STAG2_HUMAN def: "Cohesin subunit SA-2" [UniProtKB:Q8N3U4] synonym: "SCC3 homolog 2" EXACT [UniProtKB:Q8N3U4] synonym: "Stromal antigen 2" EXACT [UniProtKB:Q8N3U4] xref: EMBL:AAH01765.2 xref: EMBL:CAA99732.1 xref: EMBL:CAD38591.1 xref: EMBL:CAI40990.1 xref: UniProtKB:O00540 xref: UniProtKB:Q5JTI6 xref: UniProtKB:Q8N3U4 xref: UniProtKB:Q9H1N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005684 ! STAG2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006783 ! rad21-stag2 physical interaction relationship: participates_in CCO:I0007036 ! wapl-cspg6 physical interaction relationship: participates_in CCO:I0007037 ! wapl-cspg6-3 physical interaction relationship: participates_in CCO:I0007039 ! wapl-cspg6-1 physical interaction relationship: participates_in CCO:I0007040 ! wapl-cspg6-2 physical interaction relationship: participates_in CCO:I0007711 ! wapl-cspg6-4 physical interaction relationship: participates_in CCO:I0007712 ! wapl-cspg6-5 physical interaction relationship: participates_in CCO:I0007714 ! wapl-cspg6-7 physical interaction relationship: participates_in CCO:I0007715 ! wapl-cspg6-9 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014241 ! STAG2_HUMAN-Phosphoserine1061 relationship: transforms_into CCO:B0014242 ! STAG2_HUMAN-Phosphothreonine1160 relationship: transforms_into CCO:B0070955 ! STAG2_HUMAN-Phosphoserine1058 relationship: transforms_into CCO:B0070956 ! STAG2_HUMAN-Phosphoserine1065 [Term] id: CCO:B0001963 name: KIF2B_HUMAN def: "Kinesin-like protein KIF2B" [UniProtKB:Q8N4N8] xref: EMBL:AAH33802.1 xref: EMBL:AAK20830.2 xref: EMBL:BAB71406.1 xref: UniProtKB:Q8N4N8 xref: UniProtKB:Q96MA2 xref: UniProtKB:Q9BXG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004946 ! KIF2B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0006848 ! stau-loc84643-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001964 name: AF1L2_HUMAN def: "Actin filament-associated protein 1-like 2" [UniProtKB:Q8N4X5] xref: EMBL:AAH24314.1 xref: EMBL:AAH33212.1 xref: EMBL:BAB55135.1 xref: EMBL:BAB67807.1 xref: EMBL:CAI14967.1 xref: EMBL:CAI14968.1 xref: EMBL:CAI40128.1 xref: EMBL:CAI40129.1 xref: UniProtKB:Q8N4X5 xref: UniProtKB:Q8TB54 xref: UniProtKB:Q96PX4 xref: UniProtKB:Q96SY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004034 ! AFAP1L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000138 ! regulation of mitotic cell cycle relationship: participates_in CCO:P0002530 ! positive regulation of epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010467 ! AF1L2_HUMAN-Phosphothreonine345 relationship: transforms_into CCO:B0010468 ! AF1L2_HUMAN-Phosphotyrosine413 relationship: transforms_into CCO:B0010469 ! AF1L2_HUMAN-Phosphotyrosine668 relationship: transforms_into CCO:B0010470 ! AF1L2_HUMAN-Phosphothreonine669 relationship: transforms_into CCO:B0031289 ! AF1L2_HUMAN-Phosphotyrosine56 relationship: transforms_into CCO:B0065458 ! AF1L2_HUMAN-Phosphotyrosine383 [Term] id: CCO:B0001966 name: CD2A2_HUMAN def: "Cyclin-dependent kinase inhibitor 2A, isoform 4" [UniProtKB:Q8N726] synonym: "p14ARF" EXACT [UniProtKB:Q8N726] synonym: "p19ARF" EXACT [UniProtKB:Q8N726] xref: EMBL:AAA82236.1 xref: EMBL:AAB01737.1 xref: EMBL:AAC60649.1 xref: EMBL:AAM77919.1 xref: EMBL:AAP35666.1 xref: EMBL:CAH70601.1 xref: UniProtKB:Q13195 xref: UniProtKB:Q13399 xref: UniProtKB:Q16360 xref: UniProtKB:Q7KZR9 xref: UniProtKB:Q8N726 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004271 ! CDKN2A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008235 ! ubiquitin-protein ligase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0007256 ! huew1-cdkn2a-1 physical interaction relationship: participates_in CCO:I0007257 ! cdkn2a-huew1-3 physical interaction relationship: participates_in CCO:I0007426 ! cdkn2a-huew1-2 physical interaction relationship: participates_in CCO:I0007874 ! cdkn2a-huew1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000150 ! regulation of G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000844 ! apoptotic mitochondrial changes relationship: participates_in CCO:P0001352 ! negative regulation of B cell proliferation relationship: participates_in CCO:P0001482 ! regulation of protein stability relationship: participates_in CCO:P0001776 ! negative regulation of immature T cell proliferation in the thymus relationship: participates_in CCO:P0002772 ! somatic stem cell division [Term] id: CCO:B0001967 name: HORM2_HUMAN def: "HORMA domain-containing protein 2" [UniProtKB:Q8N7B1] xref: EMBL:AAH30013.1 xref: EMBL:BAC05388.1 xref: EMBL:CAG30227.1 xref: UniProtKB:Q8N7B1 xref: UniProtKB:Q8NHR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004825 ! HORMAD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0001969 name: Q8N855_HUMAN xref: UniProtKB:Q8N855 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001656 ! GTP binding relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001971 name: BANP_HUMAN def: "Protein BANP" [UniProtKB:Q8N9N5] synonym: "Btg3-associated nuclear protein" EXACT [UniProtKB:Q8N9N5] synonym: "Scaffold/matrix-associated region-1-binding protein" EXACT [UniProtKB:Q8N9N5] xref: EMBL:AAH09424.1 xref: EMBL:BAA91244.1 xref: EMBL:BAC04296.1 xref: UniProtKB:A8MU25 xref: UniProtKB:Q8N9N5 xref: UniProtKB:Q96GJ7 xref: UniProtKB:Q9NWY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004136 ! BANP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001972 name: BOLL_HUMAN def: "Protein boule-like" [UniProtKB:Q8N9W6] xref: EMBL:AAH33674.1 xref: EMBL:AAK58689.1 xref: EMBL:BAB71664.1 xref: EMBL:BAC04171.1 xref: UniProtKB:Q8N9W6 xref: UniProtKB:Q969U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004180 ! BOLL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001952 ! translation activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007300 ! daz1-boll-1 physical interaction relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0002631 ! positive regulation of translational initiation [Term] id: CCO:B0001973 name: SPC24_HUMAN def: "Kinetochore protein Spc24" [UniProtKB:Q8NBT2] synonym: "hSpc24" EXACT [UniProtKB:Q8NBT2] xref: EMBL:AAI05038.1 xref: EMBL:AAI05040.1 xref: EMBL:AAR88651.1 xref: EMBL:BAC11523.1 xref: UniProtKB:Q8NBT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006370 ! SPC24_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006224 ! spbc24-spbc25-4 physical interaction relationship: participates_in CCO:I0006764 ! kntc2-spbc24-3 physical interaction relationship: participates_in CCO:I0007169 ! kntc2-spbc24-4 physical interaction relationship: participates_in CCO:I0007301 ! kntc2-spbc24-1 physical interaction relationship: participates_in CCO:I0007302 ! spbc24-spbc25-3 physical interaction relationship: participates_in CCO:I0007464 ! spbc24-spbc25-1 physical interaction relationship: participates_in CCO:I0007465 ! spbc24-spbc25-2 physical interaction relationship: participates_in CCO:I0007816 ! spbc24-spbc25-5 colocalization relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: participates_in CCO:I0007932 ! kntc2-spbc24-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014174 ! SPC24_HUMAN-Phosphothreonine130 [Term] id: CCO:B0001975 name: PAPD5_HUMAN def: "PAP-associated domain-containing protein 5" [UniProtKB:Q8NDF8] synonym: "EC 2.7.7.-" EXACT [UniProtKB:Q8NDF8] synonym: "Topoisomerase-related function protein 4-2" EXACT [UniProtKB:Q8NDF8] synonym: "TRF4-2" EXACT [UniProtKB:Q8NDF8] xref: EMBL:AAD45199.1 xref: EMBL:BAA91518.1 xref: EMBL:CAD38778.1 xref: UniProtKB:Q8NDF8 xref: UniProtKB:Q9NW67 xref: UniProtKB:Q9Y6C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005258 ! PAPD5_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0001976 name: RCBT1_HUMAN def: "RCC1 and BTB domain-containing protein 1" [UniProtKB:Q8NDN9] synonym: "Chronic lymphocytic leukemia deletion region gene 7 protein" EXACT [UniProtKB:Q8NDN9] synonym: "CLL deletion region gene 7 protein" EXACT [UniProtKB:Q8NDN9] synonym: "Regulator of chromosome condensation and BTB domain-containing protein 1" EXACT [UniProtKB:Q8NDN9] xref: EMBL:AAK38372.1 xref: EMBL:BAC04833.1 xref: EMBL:CAC40027.1 xref: EMBL:CAD38683.1 xref: EMBL:CAH71047.1 xref: UniProtKB:Q8NDN9 xref: UniProtKB:Q969U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005455 ! RCBTB1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0001977 name: SMC1B_HUMAN def: "Structural maintenance of chromosomes protein 1B" [UniProtKB:Q8NDV3] synonym: "SMC1beta protein" EXACT [UniProtKB:Q8NDV3] xref: EMBL:AAI26209.1 xref: EMBL:BAC86266.1 xref: EMBL:CAD43404.2 xref: EMBL:CAQ08671.1 xref: EMBL:CAQ08672.1 xref: EMBL:CAQ09093.1 xref: EMBL:CAQ09094.1 xref: UniProtKB:A0AV46 xref: UniProtKB:B0QY23 xref: UniProtKB:B0QY24 xref: UniProtKB:Q5TIC3 xref: UniProtKB:Q6ZUF9 xref: UniProtKB:Q8NDV3 xref: UniProtKB:Q9Y3G5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005626 ! SMC1B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000076 ! sister chromatid cohesion relationship: participates_in CCO:P0000117 ! meiosis relationship: transforms_into CCO:B0014074 ! SMC1B_HUMAN-Phosphoserine882 relationship: transforms_into CCO:B0014075 ! SMC1B_HUMAN-Phosphoserine883 [Term] id: CCO:B0001978 name: PPC1B_HUMAN def: "Phosphatidic acid phosphatase type 2 domain-containing protein 1B" [UniProtKB:Q8NEB5] synonym: "EC 3.1.3.-" EXACT [UniProtKB:Q8NEB5] xref: EMBL:AAH33025.1 xref: EMBL:AAI06015.2 xref: EMBL:AAK14924.1 xref: UniProtKB:Q3KQX6 xref: UniProtKB:Q8NEB5 xref: UniProtKB:Q9BY45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005363 ! PPAPDC1B_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001979 name: MNS1_HUMAN def: "Meiosis-specific nuclear structural protein 1" [UniProtKB:Q8NEH6] xref: EMBL:AAH31046.1 xref: EMBL:AAH34991.1 xref: EMBL:BAA92077.1 xref: UniProtKB:Q8IYT6 xref: UniProtKB:Q8NEH6 xref: UniProtKB:Q9NUP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005106 ! MNS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0001980 name: DP13B_HUMAN def: "DCC-interacting protein 13-beta" [UniProtKB:Q8NEU8] synonym: "Adapter protein containing PH domain, PTB domain and leucine zipper motif 2" EXACT [UniProtKB:Q8NEU8] synonym: "Dip13-beta" EXACT [UniProtKB:Q8NEU8] xref: EMBL:AAH33731.1 xref: EMBL:AAM55530.1 xref: UniProtKB:Q8N4R7 xref: UniProtKB:Q8NEU8 xref: UniProtKB:Q9NVL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004498 ! APPL2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000805 ! NuRD complex relationship: located_in CCO:C0001339 ! early endosome membrane relationship: participates_in CCO:I0005733 ! appl1-dip13b physical interaction relationship: participates_in CCO:I0005807 ! dip13b-rab22a physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0001981 name: FLCN_HUMAN def: "Folliculin" [UniProtKB:Q8NFG4] synonym: "BHD skin lesion fibrofolliculoma protein" EXACT [UniProtKB:Q8NFG4] synonym: "Birt-Hogg-Dube syndrome protein" EXACT [UniProtKB:Q8NFG4] xref: EMBL:AAH15687.1 xref: EMBL:AAH15725.2 xref: EMBL:AAM94803.1 xref: EMBL:BAC86760.1 xref: EMBL:BAC87186.1 xref: EMBL:EAW55716.1 xref: UniProtKB:A6NJJ8 xref: UniProtKB:Q6ZRX1 xref: UniProtKB:Q8NFG4 xref: UniProtKB:Q96BD2 xref: UniProtKB:Q96BE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004650 ! FLCN_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0066201 ! FLCN_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0066202 ! FLCN_HUMAN-Phosphoserine73 [Term] id: CCO:B0001983 name: CADM4_HUMAN def: "Cell adhesion molecule 4 precursor" [UniProtKB:Q8NFZ8] synonym: "Immunoglobulin superfamily member 4C" EXACT [UniProtKB:Q8NFZ8] synonym: "Nectin-like protein 4" EXACT [UniProtKB:Q8NFZ8] synonym: "TSLC1-like protein 2" EXACT [UniProtKB:Q8NFZ8] xref: EMBL:AAC32740.1 xref: EMBL:AAM60750.1 xref: UniProtKB:Q8NFZ8 xref: UniProtKB:Q9Y4A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004211 ! CADM4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0001984 name: NEK11_HUMAN def: "Serine/threonine-protein kinase Nek11" [UniProtKB:Q8NG66] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8NG66] synonym: "Never in mitosis A-related kinase 11" EXACT [UniProtKB:Q8NG66] synonym: "NimA-related protein kinase 11" EXACT [UniProtKB:Q8NG66] xref: EMBL:AAH28587.1 xref: EMBL:BAB15672.1 xref: EMBL:BAC06350.1 xref: EMBL:BAC06351.1 xref: EMBL:CAI46114.1 xref: UniProtKB:Q5JPC0 xref: UniProtKB:Q8NG65 xref: UniProtKB:Q8NG66 xref: UniProtKB:Q8TBY1 xref: UniProtKB:Q9H5F4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005174 ! NEK11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0006321 ! nek2-nek11-8 phosphorylation relationship: participates_in CCO:I0006730 ! nek2-nek11-6 physical interaction relationship: participates_in CCO:I0006870 ! nek2-nek11-2 colocalization relationship: participates_in CCO:I0006871 ! nek2-nek11-5 physical interaction relationship: participates_in CCO:I0006975 ! nek2-nek11-1 colocalization relationship: participates_in CCO:I0006976 ! nek2-nek11-7 phosphorylation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000186 ! intra-S DNA damage checkpoint relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0001985 name: GA2L2_HUMAN def: "GAS2-like protein 2" [UniProtKB:Q8NHY3] synonym: "GAS2-related protein on chromosome 17" EXACT [UniProtKB:Q8NHY3] synonym: "Growth arrest-specific protein 2-like 2" EXACT [UniProtKB:Q8NHY3] xref: EMBL:AAM34264.1 xref: EMBL:AAM34265.1 xref: UniProtKB:Q8NHY3 xref: UniProtKB:Q8NHY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004672 ! GAS2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001986 name: CDC26_HUMAN def: "Anaphase-promoting complex subunit CDC26" [UniProtKB:Q8NHZ8] synonym: "Cell division cycle protein 26 homolog" EXACT [UniProtKB:Q8NHZ8] xref: EMBL:AAH42534.1 xref: EMBL:AAH66300.1 xref: EMBL:AAM34207.1 xref: EMBL:CAI10967.1 xref: UniProtKB:Q8NHZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004286 ! CDC26_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011066 ! CDC26_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0011067 ! CDC26_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0064189 ! CDC26_HUMAN-Phosphoserine42 [Term] id: CCO:B0001987 name: G45IP_HUMAN def: "Growth arrest and DNA-damage-inducible proteins-interacting protein 1" [UniProtKB:Q8TAE8] synonym: "CKII beta-associating protein" EXACT [UniProtKB:Q8TAE8] synonym: "CR6-interacting factor 1" EXACT [UniProtKB:Q8TAE8] synonym: "CRIF1" EXACT [UniProtKB:Q8TAE8] synonym: "p53-responsive gene 6 protein" EXACT [UniProtKB:Q8TAE8] synonym: "Papillomavirus L2-interacting nuclear protein 1" EXACT [UniProtKB:Q8TAE8] synonym: "PLINP-1" EXACT [UniProtKB:Q8TAE8] xref: EMBL:AAH04944.1 xref: EMBL:AAH13027.2 xref: EMBL:AAH13039.2 xref: EMBL:AAH69200.1 xref: EMBL:AAL85877.1 xref: EMBL:AAM10639.1 xref: EMBL:CAC82499.1 xref: EMBL:CAD22344.1 xref: UniProtKB:Q8IVM3 xref: UniProtKB:Q8TAE8 xref: UniProtKB:Q8TE51 xref: UniProtKB:Q969P9 xref: UniProtKB:Q9BSM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004670 ! GADD45GIP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001988 name: UHMK1_HUMAN def: "Serine/threonine-protein kinase Kist" [UniProtKB:Q8TAS1] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8TAS1] synonym: "Kinase interacting with stathmin" EXACT [UniProtKB:Q8TAS1] synonym: "U2AF homology motif kinase 1" EXACT [UniProtKB:Q8TAS1] xref: EMBL:AAH14917.1 xref: EMBL:AAH26046.1 xref: EMBL:CAD60192.1 xref: EMBL:CAH70392.1 xref: UniProtKB:Q8TAS1 xref: UniProtKB:Q96C22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005878 ! UHMK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0001989 name: UBA3_HUMAN def: "NEDD8-activating enzyme E1 catalytic subunit" [UniProtKB:Q8TBC4] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8TBC4] synonym: "NEDD8-activating enzyme E1C" EXACT [UniProtKB:Q8TBC4] synonym: "Ubiquitin-activating enzyme 3" EXACT [UniProtKB:Q8TBC4] synonym: "Ubiquitin-activating enzyme E1C" EXACT [UniProtKB:Q8TBC4] synonym: "Ubiquitin-like modifier-activating enzyme 3" EXACT [UniProtKB:Q8TBC4] xref: EMBL:AAC27648.1 xref: EMBL:AAH22853.1 xref: EMBL:BAA33144.1 xref: EMBL:CAB55996.2 xref: UniProtKB:O76088 xref: UniProtKB:Q8TBC4 xref: UniProtKB:Q9NTU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006416 ! UBA3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002013 ! small protein activating enzyme activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005974 ! ube1c-ube2m-1 direct interaction relationship: participates_in CCO:I0005976 ! nedd8-tp53-1 neddylation relationship: participates_in CCO:I0007022 ! appbp1-nedd8-1 physical interaction relationship: participates_in CCO:I0007023 ! appbp1-nedd8-2 physical interaction relationship: participates_in CCO:I0008348 ! ube1c-chd3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0001990 name: PIWL2_HUMAN def: "Piwi-like protein 2" [UniProtKB:Q8TC59] synonym: "Cancer/testis antigen 80" EXACT [UniProtKB:Q8TC59] synonym: "CT80" EXACT [UniProtKB:Q8TC59] xref: EMBL:AAH25995.1 xref: EMBL:AAI11752.1 xref: EMBL:BAA91558.1 xref: EMBL:BAB55155.1 xref: EMBL:BAC81342.1 xref: UniProtKB:Q8TC59 xref: UniProtKB:Q96SW6 xref: UniProtKB:Q9NW28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005319 ! PIWIL2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000119 ! meiotic prophase I [Term] id: CCO:B0001991 name: NEK9_HUMAN def: "Serine/threonine-protein kinase Nek9" [UniProtKB:Q8TD19] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8TD19] synonym: "Nek8" EXACT [UniProtKB:Q8TD19] synonym: "Nercc1 kinase" EXACT [UniProtKB:Q8TD19] synonym: "Never in mitosis A-related kinase 9" EXACT [UniProtKB:Q8TD19] synonym: "NIMA-related kinase 8" EXACT [UniProtKB:Q8TD19] synonym: "NimA-related protein kinase 9" EXACT [UniProtKB:Q8TD19] xref: EMBL:AAD31936.1 xref: EMBL:AAD31938.1 xref: EMBL:AAD31939.1 xref: EMBL:AAD31940.1 xref: EMBL:AAH09336.2 xref: EMBL:AAH93881.1 xref: EMBL:AAI12102.1 xref: EMBL:AAL05428.1 xref: EMBL:AAL87410.1 xref: EMBL:BAC02704.1 xref: UniProtKB:Q52LK6 xref: UniProtKB:Q8NCN0 xref: UniProtKB:Q8TCY4 xref: UniProtKB:Q8TD19 xref: UniProtKB:Q9UPI4 xref: UniProtKB:Q9Y6S4 xref: UniProtKB:Q9Y6S5 xref: UniProtKB:Q9Y6S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005179 ! NEK9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013151 ! NEK9_HUMAN-Phosphothreonine210 relationship: transforms_into CCO:B0013152 ! NEK9_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0013153 ! NEK9_HUMAN-Phosphothreonine333 relationship: transforms_into CCO:B0013154 ! NEK9_HUMAN-Phosphothreonine358 relationship: transforms_into CCO:B0013155 ! NEK9_HUMAN-Phosphoserine868 relationship: transforms_into CCO:B0013156 ! NEK9_HUMAN-Phosphoserine869 [Term] id: CCO:B0001992 name: BRSK1_HUMAN def: "BR serine/threonine-protein kinase 1" [UniProtKB:Q8TDC3] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8TDC3] synonym: "SAD1 kinase" EXACT [UniProtKB:Q8TDC3] synonym: "Serine/threonine kinase SAD-B" EXACT [UniProtKB:Q8TDC3] xref: EMBL:AAH16681.1 xref: EMBL:AAL87697.1 xref: EMBL:AAL87698.1 xref: EMBL:AAS10354.1 xref: EMBL:AAS86442.1 xref: EMBL:BAB47440.1 xref: EMBL:CAD38595.1 xref: EMBL:CAD38950.2 xref: UniProtKB:Q5J5B5 xref: UniProtKB:Q8NDD0 xref: UniProtKB:Q8NDR4 xref: UniProtKB:Q8TDC2 xref: UniProtKB:Q8TDC3 xref: UniProtKB:Q96AV4 xref: UniProtKB:Q96JL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004192 ! BRSK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000185 ! G2/M transition DNA damage checkpoint relationship: transforms_into CCO:B0010866 ! BRSK1_HUMAN-Phosphothreonine205 relationship: transforms_into CCO:B0010867 ! BRSK1_HUMAN-Phosphoserine209 [Term] id: CCO:B0001993 name: DLG5_HUMAN def: "Disks large homolog 5" [UniProtKB:Q8TDM6] synonym: "Discs large protein P-dlg" EXACT [UniProtKB:Q8TDM6] synonym: "Placenta and prostate DLG" EXACT [UniProtKB:Q8TDM6] xref: EMBL:AAC61295.1 xref: EMBL:AAH73996.1 xref: EMBL:AAI17696.1 xref: EMBL:AAL83937.1 xref: EMBL:AAL83938.1 xref: EMBL:BAA25509.2 xref: EMBL:BAC65420.1 xref: EMBL:CAI12103.1 xref: EMBL:CAI12104.2 xref: EMBL:CAI17323.1 xref: EMBL:CAI17324.2 xref: UniProtKB:Q149N1 xref: UniProtKB:Q5T1H7 xref: UniProtKB:Q5T1H8 xref: UniProtKB:Q6DKG3 xref: UniProtKB:Q86WC0 xref: UniProtKB:Q8TDM6 xref: UniProtKB:Q8TDM7 xref: UniProtKB:Q9UE73 xref: UniProtKB:Q9Y4E3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004479 ! DLG5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008223 ! dlst-dlg5 physical interaction relationship: participates_in CCO:I0008289 ! pfn1-dlg5 physical interaction relationship: participates_in CCO:I0008368 ! cd81-dlg5 physical interaction relationship: participates_in CCO:I0008390 ! btbd10-dlg5 physical interaction relationship: participates_in CCO:I0008438 ! terf1-dlg5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0011525 ! DLG5_HUMAN-Phosphothreonine984 relationship: transforms_into CCO:B0011526 ! DLG5_HUMAN-Phosphoserine1000 relationship: transforms_into CCO:B0011527 ! DLG5_HUMAN-Phosphothreonine1011 [Term] id: CCO:B0001994 name: CABL1_HUMAN def: "CDK5 and ABL1 enzyme substrate 1" [UniProtKB:Q8TDN4] synonym: "Ik3-1" EXACT [UniProtKB:Q8TDN4] synonym: "Interactor with CDK3 1" EXACT [UniProtKB:Q8TDN4] xref: EMBL:AAH04124.2 xref: EMBL:AAH37218.1 xref: EMBL:AAL83906.1 xref: EMBL:BAC04107.1 xref: UniProtKB:Q8N3Y8 xref: UniProtKB:Q8NA22 xref: UniProtKB:Q8TDN4 xref: UniProtKB:Q9BTG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004203 ! CABLES1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007352 ! cables1-tp53-3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000346 ! regulation of cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: participates_in CCO:P0003078 ! regulation of cell division relationship: transforms_into CCO:B0010871 ! CABL1_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0010872 ! CABL1_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0048181 ! CABL1_HUMAN-Phosphothreonine415 [Term] id: CCO:B0001995 name: RBCC1_HUMAN def: "RB1-inducible coiled-coil protein 1" [UniProtKB:Q8TDY2] xref: EMBL:AAH17556.1 xref: EMBL:BAA13194.2 xref: EMBL:BAB69690.1 xref: UniProtKB:Q8TDY2 xref: UniProtKB:Q8WVU9 xref: UniProtKB:Q92601 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005443 ! RB1CC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0013751 ! RBCC1_HUMAN-Phosphoserine237 relationship: transforms_into CCO:B0013752 ! RBCC1_HUMAN-Phosphoserine537 relationship: transforms_into CCO:B0013753 ! RBCC1_HUMAN-Phosphothreonine666 relationship: transforms_into CCO:B0069769 ! RBCC1_HUMAN-Phosphoserine624 relationship: transforms_into CCO:B0069770 ! RBCC1_HUMAN-Phosphoserine647 relationship: transforms_into CCO:B0069771 ! RBCC1_HUMAN-Phosphoserine653 [Term] id: CCO:B0001996 name: PARD3_HUMAN def: "Partitioning defective 3 homolog" [UniProtKB:Q8TEW0] synonym: "ASIP" EXACT [UniProtKB:Q8TEW0] synonym: "Atypical PKC isotype-specific-interacting protein" EXACT [UniProtKB:Q8TEW0] synonym: "CTCL tumor antigen se2-5" EXACT [UniProtKB:Q8TEW0] synonym: "PAR-3" EXACT [UniProtKB:Q8TEW0] synonym: "PAR3-alpha" EXACT [UniProtKB:Q8TEW0] synonym: "PARD-3" EXACT [UniProtKB:Q8TEW0] xref: EMBL:AAF71530.1 xref: EMBL:AAG33676.1 xref: EMBL:AAH11711.2 xref: EMBL:AAK27891.1 xref: EMBL:AAK27892.1 xref: EMBL:AAK69192.1 xref: EMBL:AAK69193.1 xref: EMBL:AAL76042.1 xref: EMBL:AAL76043.1 xref: EMBL:AAL76044.1 xref: EMBL:AAL76045.1 xref: EMBL:AAL76046.1 xref: EMBL:BAA91366.1 xref: EMBL:BAB55330.1 xref: EMBL:BAC54037.1 xref: UniProtKB:Q8TEW0 xref: UniProtKB:Q8TEW1 xref: UniProtKB:Q8TEW2 xref: UniProtKB:Q8TEW3 xref: UniProtKB:Q96K28 xref: UniProtKB:Q96RM6 xref: UniProtKB:Q96RM7 xref: UniProtKB:Q9BY57 xref: UniProtKB:Q9BY58 xref: UniProtKB:Q9HC48 xref: UniProtKB:Q9NWL4 xref: UniProtKB:Q9NYE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005266 ! PARD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006465 ! pard3-pard6a-1 physical interaction relationship: participates_in CCO:I0006466 ! pard6a-pard3-1 physical interaction relationship: participates_in CCO:I0006467 ! prcki-pard6-1 physical interaction relationship: participates_in CCO:I0007199 ! pard3-pard6b-2 physical interaction relationship: participates_in CCO:I0007200 ! pard3-pard6a-3 physical interaction relationship: participates_in CCO:I0007202 ! pard3-pard6a-2 physical interaction relationship: participates_in CCO:I0007211 ! prkci-pard3-1 physical interaction relationship: participates_in CCO:I0007212 ! ywhaz-pard3-1 physical interaction relationship: participates_in CCO:I0007218 ! pard3-ywhaz-1 physical interaction relationship: participates_in CCO:I0007219 ! ywhah-pard3-1 physical interaction relationship: participates_in CCO:I0007220 ! pard3-ywhah-1 physical interaction relationship: participates_in CCO:I0007221 ! pard3-prkci-2 physical interaction relationship: participates_in CCO:I0007231 ! pard3-pnma1-1 physical interaction relationship: participates_in CCO:I0007232 ! pnma1-pard3-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000821 ! asymmetric cell division relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013391 ! PARD3_HUMAN-Phosphoserine144 relationship: transforms_into CCO:B0013392 ! PARD3_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0013393 ! PARD3_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0013394 ! PARD3_HUMAN-Phosphoserine827 relationship: transforms_into CCO:B0013395 ! PARD3_HUMAN-Phosphotyrosine1127 relationship: transforms_into CCO:B0041170 ! PARD3_HUMAN-Phosphoserine852 relationship: transforms_into CCO:B0048349 ! PARD3_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0048350 ! PARD3_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0048351 ! PARD3_HUMAN-Phosphoserine715 relationship: transforms_into CCO:B0048352 ! PARD3_HUMAN-Phosphoserine728 relationship: transforms_into CCO:B0048353 ! PARD3_HUMAN-Phosphotyrosine1080 relationship: transforms_into CCO:B0069097 ! PARD3_HUMAN-Phosphotyrosine489 relationship: transforms_into CCO:B0069098 ! PARD3_HUMAN-Phosphoserine692 relationship: transforms_into CCO:B0069099 ! PARD3_HUMAN-Phosphoserine809 relationship: transforms_into CCO:B0069100 ! PARD3_HUMAN-Phosphoserine873 [Term] id: CCO:B0001997 name: PAR3L_HUMAN def: "Partitioning defective 3 homolog B" [UniProtKB:Q8TEW8] synonym: "Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein" EXACT [UniProtKB:Q8TEW8] synonym: "PAR3-beta" EXACT [UniProtKB:Q8TEW8] synonym: "PAR3-L protein" EXACT [UniProtKB:Q8TEW8] synonym: "Partitioning defective 3-like protein" EXACT [UniProtKB:Q8TEW8] xref: EMBL:AAL30664.1 xref: EMBL:AAL30665.1 xref: EMBL:AAL79827.1 xref: EMBL:BAB69028.1 xref: EMBL:BAB71106.1 xref: EMBL:BAB71623.1 xref: EMBL:BAC54035.1 xref: EMBL:BAC54285.1 xref: UniProtKB:Q8IUC7 xref: UniProtKB:Q8IUC9 xref: UniProtKB:Q8TEW8 xref: UniProtKB:Q96DK9 xref: UniProtKB:Q96N09 xref: UniProtKB:Q96NX6 xref: UniProtKB:Q96NX7 xref: UniProtKB:Q96Q29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005261 ! PARD3B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013387 ! PAR3L_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0013388 ! PAR3L_HUMAN-Phosphoserine730 relationship: transforms_into CCO:B0013389 ! PAR3L_HUMAN-Phosphoserine746 relationship: transforms_into CCO:B0013390 ! PAR3L_HUMAN-Phosphoserine749 relationship: transforms_into CCO:B0069096 ! PAR3L_HUMAN-Phosphotyrosine1000 [Term] id: CCO:B0001998 name: Q8TEY4_HUMAN def: "Adaptor protein FE65a2" [UniProtKB:Q8TEY4] xref: EMBL:AAL79526.1 xref: UniProtKB:Q8TEY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004076 ! APBB1_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0001999 name: HASP_HUMAN def: "Serine/threonine-protein kinase haspin" [UniProtKB:Q8TF76] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8TF76] synonym: "Germ cell-specific gene 2 protein" EXACT [UniProtKB:Q8TF76] synonym: "H-haspin" EXACT [UniProtKB:Q8TF76] synonym: "Haploid germ cell-specific nuclear protein kinase" EXACT [UniProtKB:Q8TF76] xref: EMBL:AAH47457.1 xref: EMBL:AAK30300.1 xref: EMBL:BAB21938.3 xref: EMBL:BAB71255.1 xref: UniProtKB:Q5U5K3 xref: UniProtKB:Q8TF76 xref: UniProtKB:Q96MN1 xref: UniProtKB:Q9BXS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004778 ! GSG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0012142 ! HASP_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0012143 ! HASP_HUMAN-Phosphothreonine253 relationship: transforms_into CCO:B0066752 ! HASP_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0066753 ! HASP_HUMAN-Phosphothreonine97 relationship: transforms_into CCO:B0066754 ! HASP_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0066755 ! HASP_HUMAN-Phosphoserine147 [Term] id: CCO:B0002000 name: TUSC4_HUMAN def: "Tumor suppressor candidate 4" [UniProtKB:Q8WTW4] synonym: "G21 protein" EXACT [UniProtKB:Q8WTW4] synonym: "Gene 21 protein" EXACT [UniProtKB:Q8WTW4] synonym: "NPR2-like" EXACT [UniProtKB:Q8WTW4] xref: EMBL:AAB67310.1 xref: EMBL:AAC62535.1 xref: EMBL:AAC62536.1 xref: EMBL:AAH21984.1 xref: EMBL:AAH56861.1 xref: UniProtKB:Q8WTW4 xref: UniProtKB:Q9Y249 xref: UniProtKB:Q9Y497 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005845 ! TUSC4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0002001 name: Q8WUE3_HUMAN def: "CCNE2 protein" [UniProtKB:Q8WUE3] synonym: "Cyclin E2, isoform CRA_a" EXACT [UniProtKB:Q8WUE3] xref: EMBL:AAH20729.1 xref: EMBL:EAW91727.1 xref: UniProtKB:Q8WUE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004252 ! CCNE2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002002 name: HDAC7_HUMAN def: "Histone deacetylase 7" [UniProtKB:Q8WUI4] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q8WUI4] synonym: "HD7" EXACT [UniProtKB:Q8WUI4] synonym: "HD7a" EXACT [UniProtKB:Q8WUI4] xref: EMBL:AAF63491.1 xref: EMBL:AAH06453.1 xref: EMBL:AAH20505.2 xref: EMBL:AAP84704.1 xref: EMBL:BAA91474.1 xref: EMBL:BAA91545.1 xref: EMBL:BAB15759.1 xref: EMBL:BAB55363.1 xref: EMBL:BAC56929.1 xref: EMBL:CAB55935.1 xref: UniProtKB:Q7Z5I1 xref: UniProtKB:Q8WUI4 xref: UniProtKB:Q96K01 xref: UniProtKB:Q9BR73 xref: UniProtKB:Q9H7L0 xref: UniProtKB:Q9NW41 xref: UniProtKB:Q9NWA9 xref: UniProtKB:Q9NYK9 xref: UniProtKB:Q9UFU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008805 ! HDAC7_human relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012170 ! HDAC7_HUMAN-Phosphoserine358 relationship: transforms_into CCO:B0012171 ! HDAC7_HUMAN-Phosphoserine487 relationship: transforms_into CCO:B0052420 ! HDAC7_HUMAN-Phosphotyrosine114 relationship: transforms_into CCO:B0066776 ! HDAC7_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0066777 ! HDAC7_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0066778 ! HDAC7_HUMAN-Phosphothreonine286 relationship: transforms_into CCO:B0066779 ! HDAC7_HUMAN-Phosphoserine486 [Term] id: CCO:B0002003 name: SKA2_HUMAN def: "Spindle and kinetochore-associated protein 2" [UniProtKB:Q8WVK7] synonym: "Protein FAM33A" EXACT [UniProtKB:Q8WVK7] xref: EMBL:AAH17873.1 xref: EMBL:AAI06004.1 xref: UniProtKB:A6NIL3 xref: UniProtKB:Q8WVK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005620 ! FAM33A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000388 ! spindle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002004 name: STAG1_HUMAN def: "Cohesin subunit SA-1" [UniProtKB:Q8WVM7] synonym: "SCC3 homolog 1" EXACT [UniProtKB:Q8WVM7] synonym: "Stromal antigen 1" EXACT [UniProtKB:Q8WVM7] xref: EMBL:AAH17735.1 xref: EMBL:CAA99731.1 xref: UniProtKB:O00539 xref: UniProtKB:Q8WVM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005683 ! STAG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007036 ! wapl-cspg6 physical interaction relationship: participates_in CCO:I0007037 ! wapl-cspg6-3 physical interaction relationship: participates_in CCO:I0007712 ! wapl-cspg6-5 physical interaction relationship: participates_in CCO:I0007713 ! wapl-cspg6-6 physical interaction relationship: participates_in CCO:I0007715 ! wapl-cspg6-9 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014239 ! STAG1_HUMAN-Phosphoserine1069 relationship: transforms_into CCO:B0014240 ! STAG1_HUMAN-Phosphoserine1070 relationship: transforms_into CCO:B0070952 ! STAG1_HUMAN-Phosphoserine1062 relationship: transforms_into CCO:B0070953 ! STAG1_HUMAN-Phosphoserine1065 relationship: transforms_into CCO:B0070954 ! STAG1_HUMAN-Phosphoserine1067 [Term] id: CCO:B0002005 name: PCNP_HUMAN def: "PEST proteolytic signal-containing nuclear protein" [UniProtKB:Q8WW12] synonym: "PCNP" EXACT [UniProtKB:Q8WW12] synonym: "PEST-containing nuclear protein" EXACT [UniProtKB:Q8WW12] xref: EMBL:AAH13916.1 xref: EMBL:AAH22001.1 xref: EMBL:BAB03501.1 xref: EMBL:CAH10470.1 xref: UniProtKB:Q6AI44 xref: UniProtKB:Q8WW12 xref: UniProtKB:Q96CU3 xref: UniProtKB:Q9NS81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005279 ! PCNP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0013433 ! PCNP_HUMAN-Phosphothreonine66 relationship: transforms_into CCO:B0013434 ! PCNP_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0013435 ! PCNP_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0013436 ! PCNP_HUMAN-Phosphothreonine139 relationship: transforms_into CCO:B0013437 ! PCNP_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0013438 ! PCNP_HUMAN-Phosphoserine147 relationship: transforms_into CCO:B0069153 ! PCNP_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0069154 ! PCNP_HUMAN-Phosphoserine119 [Term] id: CCO:B0002006 name: CKAP2_HUMAN def: "Cytoskeleton-associated protein 2" [UniProtKB:Q8WWK9] synonym: "CTCL tumor antigen se20-10" EXACT [UniProtKB:Q8WWK9] synonym: "Tumor- and microtubule-associated protein" EXACT [UniProtKB:Q8WWK9] xref: EMBL:AAG33675.1 xref: EMBL:AAH10901.1 xref: EMBL:AAI05807.1 xref: EMBL:AAI30297.1 xref: EMBL:AAL47212.1 xref: EMBL:AAL47213.1 xref: EMBL:ABQ59042.1 xref: EMBL:BAA91788.1 xref: EMBL:BAB14345.1 xref: EMBL:CAB66782.2 xref: EMBL:CAC17466.1 xref: EMBL:CAD22295.1 xref: EMBL:CAH71660.2 xref: EMBL:CAH71661.2 xref: UniProtKB:A2BDE0 xref: UniProtKB:A5YM58 xref: UniProtKB:Q3KRA5 xref: UniProtKB:Q5VXB4 xref: UniProtKB:Q8IWV5 xref: UniProtKB:Q8IWV6 xref: UniProtKB:Q8WWK9 xref: UniProtKB:Q96FH9 xref: UniProtKB:Q9H012 xref: UniProtKB:Q9H0D0 xref: UniProtKB:Q9H988 xref: UniProtKB:Q9HC49 xref: UniProtKB:Q9NVG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004361 ! CKAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011235 ! CKAP2_HUMAN-Phosphoserine534 relationship: transforms_into CCO:B0011236 ! CKAP2_HUMAN-Phosphothreonine579 relationship: transforms_into CCO:B0011237 ! CKAP2_HUMAN-Phosphothreonine582 relationship: transforms_into CCO:B0011238 ! CKAP2_HUMAN-Phosphothreonine597 relationship: transforms_into CCO:B0011239 ! CKAP2_HUMAN-Phosphoserine602 relationship: transforms_into CCO:B0011240 ! CKAP2_HUMAN-Phosphoserine614 relationship: transforms_into CCO:B0011241 ! CKAP2_HUMAN-Phosphothreonine623 relationship: transforms_into CCO:B0064364 ! CKAP2_HUMAN-Phosphoserine595 relationship: transforms_into CCO:B0064365 ! CKAP2_HUMAN-Phosphothreonine596 relationship: transforms_into CCO:B0064366 ! CKAP2_HUMAN-Phosphotyrosine599 [Term] id: CCO:B0002007 name: CCNB3_HUMAN def: "G2/mitotic-specific cyclin-B3" [UniProtKB:Q8WWL7] xref: EMBL:CAB70806.1 xref: EMBL:CAC40024.1 xref: EMBL:CAC40025.1 xref: EMBL:CAC40026.1 xref: EMBL:CAC94915.1 xref: EMBL:CAI41321.1 xref: EMBL:CAI43221.1 xref: EMBL:EAW89923.1 xref: UniProtKB:B1AQI5 xref: UniProtKB:Q8WWL7 xref: UniProtKB:Q96SB5 xref: UniProtKB:Q96SB6 xref: UniProtKB:Q96SB7 xref: UniProtKB:Q9NT38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004246 ! CCNB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007901 ! cyclinb3_cdk2_human direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002008 name: RASF5_HUMAN def: "Ras association domain-containing protein 5" [UniProtKB:Q8WWW0] synonym: "New ras effector 1" EXACT [UniProtKB:Q8WWW0] synonym: "RAPL" EXACT [UniProtKB:Q8WWW0] synonym: "Regulator for cell adhesion and polarization enriched in lymphoid tissues" EXACT [UniProtKB:Q8WWW0] xref: EMBL:AAH04270.1 xref: EMBL:AAH07203.1 xref: EMBL:AAH42651.1 xref: EMBL:AAL38592.1 xref: EMBL:AAL40388.1 xref: EMBL:AAL40389.1 xref: EMBL:AAO61668.1 xref: EMBL:AAP83360.1 xref: EMBL:CAI13536.1 xref: EMBL:CAI13537.1 xref: EMBL:CAI13538.1 xref: EMBL:CAI13542.1 xref: EMBL:CAI15252.1 xref: EMBL:CAI15253.1 xref: EMBL:CAI15254.1 xref: EMBL:CAI15256.1 xref: EMBL:CAI46164.1 xref: UniProtKB:Q5SY32 xref: UniProtKB:Q8WWV9 xref: UniProtKB:Q8WWW0 xref: UniProtKB:Q8WXF4 xref: UniProtKB:Q9BT99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005432 ! RASSF5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0006951 ! stk4-rassf5-1 physical interaction relationship: participates_in CCO:I0007001 ! hras1-rassf5-2 physical interaction relationship: participates_in CCO:I0007002 ! rap1a-itgal-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0002009 name: ATRIP_HUMAN def: "ATR-interacting protein" [UniProtKB:Q8WXE1] synonym: "ATM and Rad3-related-interacting protein" EXACT [UniProtKB:Q8WXE1] xref: EMBL:AAH14153.2 xref: EMBL:AAH20563.1 xref: EMBL:AAH30597.1 xref: EMBL:AAL38042.1 xref: EMBL:BAB14029.1 xref: UniProtKB:Q8NHQ2 xref: UniProtKB:Q8WUG7 xref: UniProtKB:Q8WXE1 xref: UniProtKB:Q96CL3 xref: UniProtKB:Q9HA30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004122 ! ATRIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005811 ! atrip-ribc2 physical interaction relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0010694 ! ATRIP_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0063659 ! ATRIP_HUMAN-Phosphoserine224 [Term] id: CCO:B0002010 name: MADD_HUMAN def: "MAP kinase-activating death domain protein" [UniProtKB:Q8WXG6] synonym: "Differentially expressed in normal and neoplastic cells" EXACT [UniProtKB:Q8WXG6] synonym: "Insulinoma glucagonoma clone 20" EXACT [UniProtKB:Q8WXG6] synonym: "Rab3 GDP/GTP exchange factor" EXACT [UniProtKB:Q8WXG6] xref: EMBL:AAB57735.1 xref: EMBL:AAD12154.1 xref: EMBL:AAH40484.1 xref: EMBL:AAL35261.1 xref: EMBL:AAL40265.1 xref: EMBL:AAL40266.1 xref: EMBL:AAL40267.1 xref: EMBL:AAL40268.1 xref: EMBL:BAA20814.2 xref: UniProtKB:O15065 xref: UniProtKB:O15293 xref: UniProtKB:Q15732 xref: UniProtKB:Q15741 xref: UniProtKB:Q8IWD7 xref: UniProtKB:Q8WXG3 xref: UniProtKB:Q8WXG4 xref: UniProtKB:Q8WXG5 xref: UniProtKB:Q8WXG6 xref: UniProtKB:Q8WZ63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005013 ! MADD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000346 ! regulation of cell cycle relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0012757 ! MADD_HUMAN-Phosphoserine1059 relationship: transforms_into CCO:B0012758 ! MADD_HUMAN-Phosphothreonine1061 relationship: transforms_into CCO:B0067843 ! MADD_HUMAN-Phosphoserine818 relationship: transforms_into CCO:B0067844 ! MADD_HUMAN-Phosphoserine820 relationship: transforms_into CCO:B0067845 ! MADD_HUMAN-Phosphoserine921 relationship: transforms_into CCO:B0067846 ! MADD_HUMAN-Phosphoserine1270 [Term] id: CCO:B0002011 name: SEPT1_HUMAN def: "Septin-1" [UniProtKB:Q8WYJ6] synonym: "LARP" EXACT [UniProtKB:Q8WYJ6] synonym: "Peanut-like protein 3" EXACT [UniProtKB:Q8WYJ6] synonym: "Serologically defined breast cancer antigen NY-BR-24" EXACT [UniProtKB:Q8WYJ6] xref: EMBL:AAG48256.1 xref: EMBL:AAH12161.1 xref: EMBL:AAK61491.1 xref: EMBL:AAL40393.1 xref: UniProtKB:Q8NEZ1 xref: UniProtKB:Q8WYJ6 xref: UniProtKB:Q96EL4 xref: UniProtKB:Q9H285 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005584 ! SEPT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:I0005780 ! sept1-sept6 physical interaction relationship: participates_in CCO:I0005863 ! sept1-tollip physical interaction relationship: participates_in CCO:I0005935 ! sept1-sept1 physical interaction relationship: participates_in CCO:I0006031 ! sept1-aurkb-5 phosphorylation relationship: participates_in CCO:I0006206 ! sept1-aurkb-2 physical interaction relationship: participates_in CCO:I0006533 ! sept1-aurkb-3 physical interaction relationship: participates_in CCO:I0006731 ! sept1-aurkb-4 physical interaction relationship: participates_in CCO:I0007357 ! sept1-aurkb-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002012 name: RSPH1_HUMAN def: "Radial spoke head 1 homolog" [UniProtKB:Q8WYR4] synonym: "Cancer/testis antigen 79" EXACT [UniProtKB:Q8WYR4] synonym: "CT79" EXACT [UniProtKB:Q8WYR4] synonym: "Male meiotic metaphase chromosome-associated acidic protein" EXACT [UniProtKB:Q8WYR4] synonym: "Meichroacidin" EXACT [UniProtKB:Q8WYR4] synonym: "Testis-specific gene A2 protein" EXACT [UniProtKB:Q8WYR4] xref: EMBL:AAI01520.1 xref: EMBL:AAI13368.1 xref: EMBL:BAB83694.1 xref: EMBL:BAB92995.1 xref: UniProtKB:Q3MJA1 xref: UniProtKB:Q8WYR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005542 ! RSPH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0002013 name: TITIN_HUMAN def: "Titin" [UniProtKB:Q8WZ42] synonym: "Connectin" EXACT [UniProtKB:Q8WZ42] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8WZ42] synonym: "Rhabdomyosarcoma antigen MU-RMS-40.14" EXACT [UniProtKB:Q8WZ42] xref: EMBL:AAD22603.1 xref: EMBL:AAD22604.1 xref: EMBL:AAH13396.1 xref: EMBL:AAH58824.1 xref: EMBL:AAH70170.1 xref: EMBL:AAI07798.1 xref: EMBL:AAP80791.1 xref: EMBL:ABB55264.1 xref: EMBL:CAA45938.1 xref: EMBL:CAA45939.1 xref: EMBL:CAA45940.1 xref: EMBL:CAA49245.1 xref: EMBL:CAA58243.1 xref: EMBL:CAA62188.1 xref: EMBL:CAA62189.1 xref: EMBL:CAA66795.1 xref: EMBL:CAA66796.1 xref: EMBL:CAD12455.1 xref: EMBL:CAD12456.1 xref: EMBL:CAD12457.1 xref: EMBL:CAD12458.1 xref: EMBL:CAD12459.1 xref: EMBL:CAD28458.1 xref: UniProtKB:Q10465 xref: UniProtKB:Q10466 xref: UniProtKB:Q15598 xref: UniProtKB:Q2XUS3 xref: UniProtKB:Q32Q60 xref: UniProtKB:Q4U1Z6 xref: UniProtKB:Q6NSG0 xref: UniProtKB:Q6PDB1 xref: UniProtKB:Q6PJP0 xref: UniProtKB:Q7KYM2 xref: UniProtKB:Q7KYN4 xref: UniProtKB:Q7KYN5 xref: UniProtKB:Q7LDM3 xref: UniProtKB:Q7Z2X3 xref: UniProtKB:Q8TCG8 xref: UniProtKB:Q8WZ42 xref: UniProtKB:Q8WZ51 xref: UniProtKB:Q8WZ52 xref: UniProtKB:Q8WZ53 xref: UniProtKB:Q8WZB3 xref: UniProtKB:Q92761 xref: UniProtKB:Q92762 xref: UniProtKB:Q9UD97 xref: UniProtKB:Q9UP84 xref: UniProtKB:Q9Y6L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005786 ! TTN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006073 ! ttn-tcap direct interaction relationship: participates_in CCO:I0006732 ! actn2-ttn-4 physical interaction relationship: participates_in CCO:I0006733 ! ttn-ttn-1 physical interaction relationship: participates_in CCO:I0006743 ! ttn-obscn-3 physical interaction relationship: participates_in CCO:I0006874 ! ttn-actn2-5 physical interaction relationship: participates_in CCO:I0007004 ! ttn-obscn-1 physical interaction relationship: participates_in CCO:I0007124 ! actn2-ttn-3 physical interaction relationship: participates_in CCO:I0007125 ! actn2-ttn-6 physical interaction relationship: participates_in CCO:I0007452 ! ttn-obscn-2 physical interaction relationship: participates_in CCO:I0007571 ! ttn-actn2-1 physical interaction relationship: participates_in CCO:I0007758 ! actn2-ttn-2 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0014381 ! TITIN_HUMAN-Phosphoserine33938 relationship: transforms_into CCO:B0014382 ! TITIN_HUMAN-Phosphoserine33942 relationship: transforms_into CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: transforms_into CCO:B0014384 ! TITIN_HUMAN-Phosphothreonine9207 relationship: transforms_into CCO:B0014385 ! TITIN_HUMAN-Phosphoserine22525 relationship: transforms_into CCO:B0014386 ! TITIN_HUMAN-Phosphoserine22534 relationship: transforms_into CCO:B0014387 ! TITIN_HUMAN-Phosphotyrosine32341 relationship: transforms_into CCO:B0036036 ! TITIN_HUMAN-Phosphoserine4065 relationship: transforms_into CCO:B0036037 ! TITIN_HUMAN-Phosphoserine4068 relationship: transforms_into CCO:B0048412 ! TITIN_HUMAN-Phosphotyrosine8490 [Term] id: CCO:B0002014 name: TSC1_HUMAN def: "Hamartin" [UniProtKB:Q92574] synonym: "Tuberous sclerosis 1 protein" EXACT [UniProtKB:Q92574] xref: EMBL:AAC51674.1 xref: EMBL:AAF61948.1 xref: EMBL:BAA13436.1 xref: UniProtKB:Q92574 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005839 ! TSC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000507 ! regulation of cell-matrix adhesion relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0001431 ! negative regulation of protein ubiquitination relationship: participates_in CCO:P0001523 ! negative regulation of TOR signaling pathway relationship: participates_in CCO:P0001689 ! activation of Rho GTPase activity relationship: participates_in CCO:P0003104 ! regulation of stress fiber formation relationship: participates_in CCO:P0003155 ! positive regulation of focal adhesion formation relationship: transforms_into CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: transforms_into CCO:B0014541 ! TSC1_HUMAN-Phosphoserine1102 relationship: transforms_into CCO:B0071595 ! TSC1_HUMAN-Phosphoserine511 relationship: transforms_into CCO:B0071596 ! TSC1_HUMAN-Phosphoserine598 [Term] id: CCO:B0002015 name: SEPT8_HUMAN def: "Septin-8" [UniProtKB:Q92599] xref: EMBL:AAG09407.1 xref: EMBL:AAH01329.1 xref: EMBL:AAO13878.1 xref: EMBL:AAO13879.1 xref: EMBL:AAO13880.1 xref: EMBL:BAA13193.1 xref: UniProtKB:Q8IX36 xref: UniProtKB:Q8IX37 xref: UniProtKB:Q92599 xref: UniProtKB:Q9BVB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005591 ! SEPT8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006898 ! sept5-sept8 physical interaction relationship: participates_in CCO:I0007373 ! sept5-sept8-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0014008 ! SEPT8_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0014009 ! SEPT8_HUMAN-Phosphoserine10 [Term] id: CCO:B0002016 name: RAD54_HUMAN def: "DNA repair and recombination protein RAD54-like" [UniProtKB:Q92698] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q92698] synonym: "hHR54" EXACT [UniProtKB:Q92698] synonym: "hRAD54" EXACT [UniProtKB:Q92698] synonym: "RAD54 homolog" EXACT [UniProtKB:Q92698] xref: EMBL:AAI21060.1 xref: EMBL:AAI21061.1 xref: EMBL:AAT38113.1 xref: EMBL:CAA66379.1 xref: EMBL:CAI22117.1 xref: UniProtKB:Q5TE31 xref: UniProtKB:Q6IUY3 xref: UniProtKB:Q92698 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005418 ! RAD54L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0002017 name: DDX12_HUMAN def: "Probable ATP-dependent RNA helicase DDX12" [UniProtKB:Q92771] synonym: "CHL1-related protein 2" EXACT [UniProtKB:Q92771] synonym: "DEAD/H box protein 12" EXACT [UniProtKB:Q92771] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q92771] synonym: "hCHLR2" EXACT [UniProtKB:Q92771] xref: EMBL:AAB06963.1 xref: UniProtKB:Q92771 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004455 ! DDX12_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002018 name: SC65_HUMAN def: "Synaptonemal complex protein SC65" [UniProtKB:Q92791] synonym: "Nucleolar autoantigen No55" EXACT [UniProtKB:Q92791] xref: EMBL:AAC51792.1 xref: EMBL:AAH01047.1 xref: EMBL:AAH07942.1 xref: EMBL:AAH11701.1 xref: EMBL:BAD96665.1 xref: EMBL:CAC16786.1 xref: UniProtKB:Q53GI6 xref: UniProtKB:Q92791 xref: UniProtKB:Q9H4F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005200 ! SC65_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000122 ! synaptonemal complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000121 ! synaptonemal complex assembly relationship: transforms_into CCO:B0048387 ! SC65_HUMAN-Phosphotyrosine234 [Term] id: CCO:B0002019 name: PCAF_HUMAN def: "Histone acetyltransferase PCAF" [UniProtKB:Q92831] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q92831] synonym: "Histone acetylase PCAF" EXACT [UniProtKB:Q92831] synonym: "P/CAF" EXACT [UniProtKB:Q92831] synonym: "P300/CBP-associated factor" EXACT [UniProtKB:Q92831] xref: EMBL:AAC50890.2 xref: EMBL:AAH60823.1 xref: EMBL:AAH70075.1 xref: UniProtKB:Q6NSK1 xref: UniProtKB:Q92831 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005274 ! PCAF_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0000815 ! H3/H4 histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000011 ! histone acetyltransferase complex relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006223 ! pcaf-hif1a physical interaction relationship: participates_in CCO:I0006352 ! pcaf-hif1a-1 physical interaction relationship: participates_in CCO:I0006564 ! tp53-nfya-3 physical interaction relationship: participates_in CCO:I0006917 ! nfya-tp53 physical interaction relationship: participates_in CCO:I0006919 ! tp53-nfya-5 physical interaction relationship: participates_in CCO:I0006958 ! sirt2-pcaf-myod1-2 physical interaction relationship: participates_in CCO:I0007368 ! pcaf-p66a physical interaction relationship: participates_in CCO:I0007369 ! pcaf-p66b-1 physical interaction relationship: participates_in CCO:I0007534 ! sirt2-pcaf-1 physical interaction relationship: participates_in CCO:I0007535 ! sirt2-pcaf-2 physical interaction relationship: participates_in CCO:I0007536 ! sirt2-pcaf-myod1-1 physical interaction relationship: participates_in CCO:I0007847 ! sirt2-pcaf-3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0041171 ! PCAF_HUMAN-Phosphoserine40 relationship: transforms_into CCO:B0069151 ! PCAF_HUMAN-Phosphotyrosine729 [Term] id: CCO:B0002020 name: APBB2_HUMAN def: "Amyloid beta A4 precursor protein-binding family B member 2" [UniProtKB:Q92870] synonym: "Fe65-like protein" EXACT [UniProtKB:Q92870] xref: EMBL:AAC50805.1 xref: EMBL:AAH27946.2 xref: UniProtKB:Q8IUI6 xref: UniProtKB:Q92870 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004077 ! APBB2_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0006047 ! aplp2-apbb2-1 physical interaction relationship: participates_in CCO:I0006669 ! apbb2-app-2 physical interaction relationship: participates_in CCO:I0006992 ! apbb2 -app-1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0002021 name: RAD50_HUMAN def: "DNA repair protein RAD50" [UniProtKB:Q92878] synonym: "EC 3.6.-.-" EXACT [UniProtKB:Q92878] synonym: "hRAD50" EXACT [UniProtKB:Q92878] xref: EMBL:AAB07119.1 xref: EMBL:AAD50325.1 xref: EMBL:AAD50326.1 xref: EMBL:AAH62603.1 xref: EMBL:AAH73850.1 xref: EMBL:CAA99729.1 xref: UniProtKB:O43254 xref: UniProtKB:Q6GMT7 xref: UniProtKB:Q6P5X3 xref: UniProtKB:Q92878 xref: UniProtKB:Q9UP86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005415 ! RAD50_human relationship: has_function CCO:F0000005 ! single-stranded DNA specific endodeoxyribonuclease activity relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0001060 ! Mre11 complex relationship: participates_in CCO:I0006748 ! brca1-trrap-2 physical interaction relationship: participates_in CCO:I0006749 ! brca1-trrap-3 physical interaction relationship: participates_in CCO:I0006960 ! mdc1-atm-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000399 ! regulation of mitotic recombination relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: transforms_into CCO:B0013665 ! RAD50_HUMAN-Phosphoserine237 relationship: transforms_into CCO:B0013666 ! RAD50_HUMAN-Phosphoserine635 relationship: transforms_into CCO:B0013667 ! RAD50_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0013668 ! RAD50_HUMAN-Phosphothreonine690 [Term] id: CCO:B0002022 name: NGN1_HUMAN def: "Neurogenin-1" [UniProtKB:Q92886] synonym: "NeuroD3" EXACT [UniProtKB:Q92886] synonym: "Neurogenic basic-helix-loop-helix protein" EXACT [UniProtKB:Q92886] synonym: "Neurogenic differentiation factor 3" EXACT [UniProtKB:Q92886] xref: EMBL:AAB37575.1 xref: EMBL:AAH08687.1 xref: EMBL:AAH28226.1 xref: UniProtKB:Q92886 xref: UniProtKB:Q96HE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005192 ! NEUROG1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000177 ! positive regulation of exit from mitosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0002023 name: ARHG1_HUMAN def: "Rho guanine nucleotide exchange factor 1" [UniProtKB:Q92888] synonym: "115 kDa guanine nucleotide exchange factor" EXACT [UniProtKB:Q92888] synonym: "p115-RhoGEF" EXACT [UniProtKB:Q92888] synonym: "p115RhoGEF" EXACT [UniProtKB:Q92888] synonym: "Sub1.5" EXACT [UniProtKB:Q92888] xref: EMBL:AAB17896.1 xref: EMBL:AAH05155.2 xref: EMBL:AAH11726.1 xref: EMBL:AAH34013.2 xref: EMBL:AAP36089.1 xref: EMBL:CAA70356.1 xref: UniProtKB:O00513 xref: UniProtKB:Q8N4J4 xref: UniProtKB:Q92888 xref: UniProtKB:Q96BF4 xref: UniProtKB:Q96F17 xref: UniProtKB:Q9BSB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004090 ! ARHGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006034 ! argef1-gbf1-6 colocalization relationship: participates_in CCO:I0006706 ! gna13-arhgef1-1 physical interaction relationship: participates_in CCO:I0006707 ! gna13-arhgef1-2 physical interaction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0065711 ! ARHG1_HUMAN-Phosphoserine863 [Term] id: CCO:B0002024 name: RENT1_HUMAN def: "Regulator of nonsense transcripts 1" [UniProtKB:Q92900] synonym: "ATP-dependent helicase RENT1" EXACT [UniProtKB:Q92900] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q92900] synonym: "hUpf1" EXACT [UniProtKB:Q92900] synonym: "Nonsense mRNA reducing factor 1" EXACT [UniProtKB:Q92900] synonym: "NORF1" EXACT [UniProtKB:Q92900] synonym: "Up-frameshift suppressor 1 homolog" EXACT [UniProtKB:Q92900] xref: EMBL:AAB94785.1 xref: EMBL:AAC26788.1 xref: EMBL:AAC50771.1 xref: EMBL:AAC51140.1 xref: EMBL:AAH39817.1 xref: EMBL:BAA19664.2 xref: UniProtKB:O00239 xref: UniProtKB:O43343 xref: UniProtKB:Q86Z25 xref: UniProtKB:Q92842 xref: UniProtKB:Q92900 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005467 ! UPF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006015 ! lsm8-rent1 physical interaction relationship: participates_in CCO:I0006228 ! rent1-dcp2 physical interaction relationship: participates_in CCO:I0006229 ! dcp1a-upf1 physical interaction relationship: participates_in CCO:I0006230 ! dcp2-upf physical interaction relationship: participates_in CCO:I0006231 ! upf1-dcp1a-2 physical interaction relationship: participates_in CCO:I0006239 ! upf1-dcp1a-3 physical interaction relationship: participates_in CCO:I0006240 ! upf1-dcp1a-4 physical interaction relationship: participates_in CCO:I0006241 ! upf1-dcp1a-5 physical interaction relationship: participates_in CCO:I0006301 ! rent1-stau-2 physical interaction relationship: participates_in CCO:I0006499 ! rent1-u315 physical interaction relationship: participates_in CCO:I0006500 ! rent1-plekhb2 physical interaction relationship: participates_in CCO:I0006501 ! rent1-acas2 physical interaction relationship: participates_in CCO:I0006502 ! rent1-bat5 physical interaction relationship: participates_in CCO:I0006503 ! rent1-pepp2 physical interaction relationship: participates_in CCO:I0006504 ! rent1-c316g12_3 physical interaction relationship: participates_in CCO:I0006715 ! rent1-stau-3 physical interaction relationship: participates_in CCO:I0006716 ! rent1-stau-4 physical interaction relationship: participates_in CCO:I0007014 ! upf1-dcp1a physical interaction relationship: participates_in CCO:I0007015 ! upf1-dcp2 physical interaction relationship: participates_in CCO:I0007016 ! upf1-rcd8 physical interaction relationship: participates_in CCO:I0007249 ! rent1-stau-6 physical interaction relationship: participates_in CCO:I0007552 ! rent1-stau-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000664 ! regulation of translational termination relationship: transforms_into CCO:B0013819 ! RENT1_HUMAN-Phosphoserine1089 relationship: transforms_into CCO:B0013820 ! RENT1_HUMAN-Phosphoserine1107 relationship: transforms_into CCO:B0013821 ! RENT1_HUMAN-Phosphoserine1127 relationship: transforms_into CCO:B0048373 ! RENT1_HUMAN-Phosphotyrosine1129 [Term] id: CCO:B0002025 name: CSN5_HUMAN def: "COP9 signalosome complex subunit 5" [UniProtKB:Q92905] synonym: "EC 3.4.-.-" EXACT [UniProtKB:Q92905] synonym: "Jun activation domain-binding protein 1" EXACT [UniProtKB:Q92905] synonym: "SGN5" EXACT [UniProtKB:Q92905] synonym: "Signalosome subunit 5" EXACT [UniProtKB:Q92905] xref: EMBL:AAB16847.1 xref: EMBL:AAD03468.1 xref: EMBL:AAH01187.1 xref: EMBL:AAH01859.1 xref: EMBL:AAH07272.1 xref: EMBL:AAL82571.1 xref: EMBL:CAG46479.1 xref: EMBL:CAH10375.1 xref: UniProtKB:O15386 xref: UniProtKB:Q6AW95 xref: UniProtKB:Q86WQ4 xref: UniProtKB:Q92905 xref: UniProtKB:Q9BQ17 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004408 ! COPS5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006461 ! cops5-cdkn1b physical interaction relationship: participates_in CCO:I0006658 ! gfi1b-cops5 physical interaction relationship: participates_in CCO:I0007044 ! cdn1b-cops5 colocalization relationship: participates_in CCO:I0007101 ! trx-jab1-2 physical interaction relationship: participates_in CCO:I0007102 ! jab1-trx physical interaction relationship: participates_in CCO:I0007252 ! trx-jab1-5 physical interaction relationship: participates_in CCO:I0007253 ! trx-jab1-cdn1b physical interaction relationship: participates_in CCO:I0007425 ! trx-jab1-4 physical interaction relationship: participates_in CCO:I0007563 ! trx-jab1-1 physical interaction relationship: participates_in CCO:I0007863 ! trx-jab1 physical interaction relationship: transforms_into CCO:B0011362 ! CSN5_HUMAN-N-acetylalanine2 [Term] id: CCO:B0002026 name: NAT6_HUMAN def: "N-acetyltransferase 6" [UniProtKB:Q93015] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q93015] synonym: "Protein fus-2" EXACT [UniProtKB:Q93015] synonym: "Protein fusion-2" EXACT [UniProtKB:Q93015] xref: EMBL:AAC02732.1 xref: EMBL:AAC70912.1 xref: EMBL:AAC70913.1 xref: EMBL:AAH04483.2 xref: UniProtKB:Q93014 xref: UniProtKB:Q93015 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005157 ! NAT6_human relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008451 ! c2f-nat6 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0002027 name: CUL5_HUMAN def: "Cullin-5" [UniProtKB:Q93034] synonym: "CUL-5" EXACT [UniProtKB:Q93034] synonym: "VACM-1" EXACT [UniProtKB:Q93034] synonym: "Vasopressin-activated calcium-mobilizing receptor" EXACT [UniProtKB:Q93034] xref: EMBL:AAB70253.1 xref: EMBL:AAH63306.1 xref: EMBL:AAK07472.1 xref: EMBL:CAA57465.1 xref: UniProtKB:O14766 xref: UniProtKB:Q93034 xref: UniProtKB:Q9BZC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004426 ! CUL5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: transforms_into CCO:B0064595 ! CUL5_HUMAN-Phosphothreonine210 [Term] id: CCO:B0002028 name: EXT2_HUMAN def: "Exostosin-2" [UniProtKB:Q93063] synonym: "EC 2.4.1.224" EXACT [UniProtKB:Q93063] synonym: "EC 2.4.1.225" EXACT [UniProtKB:Q93063] synonym: "Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase" EXACT [UniProtKB:Q93063] synonym: "Multiple exostoses protein 2" EXACT [UniProtKB:Q93063] synonym: "Putative tumor suppressor protein EXT2" EXACT [UniProtKB:Q93063] xref: EMBL:AAB07008.1 xref: EMBL:AAB62718.1 xref: EMBL:AAC50764.1 xref: EMBL:AAC51219.1 xref: EMBL:AAH10058.1 xref: UniProtKB:O15288 xref: UniProtKB:Q93063 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004603 ! EXT2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001851 ! acetylglucosaminyltransferase activity relationship: has_function CCO:F0002526 ! glucuronosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0005661 ! heparan sulfate N-acetylglucosaminyltransferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007845 ! glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity relationship: has_function CCO:F0007846 ! N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0002029 name: TP4A1_HUMAN def: "Protein tyrosine phosphatase type IVA 1" [UniProtKB:Q93096] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q93096] synonym: "PRL-1" EXACT [UniProtKB:Q93096] synonym: "Protein-tyrosine phosphatase 4a1" EXACT [UniProtKB:Q93096] synonym: "Protein-tyrosine phosphatase of regenerating liver 1" EXACT [UniProtKB:Q93096] synonym: "PTP(CAAXI)" EXACT [UniProtKB:Q93096] xref: EMBL:AAB09080.1 xref: EMBL:AAB40597.1 xref: EMBL:AAC39836.1 xref: EMBL:AAH23975.1 xref: EMBL:AAH45571.1 xref: EMBL:CAC12761.1 xref: EMBL:CAH18292.1 xref: UniProtKB:O00648 xref: UniProtKB:Q49A54 xref: UniProtKB:Q93096 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005814 ! PTP4A1_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002030 name: TBRG4_HUMAN def: "Protein TBRG4" [UniProtKB:Q969Z0] synonym: "Cell cycle progression protein 2" EXACT [UniProtKB:Q969Z0] synonym: "Cell cycle progression restoration protein 2" EXACT [UniProtKB:Q969Z0] synonym: "FAST kinase domain-containing protein 4" EXACT [UniProtKB:Q969Z0] synonym: "Transforming growth factor beta regulator 4" EXACT [UniProtKB:Q969Z0] xref: EMBL:AAB69312.1 xref: EMBL:AAH02732.2 xref: EMBL:AAH14918.1 xref: EMBL:AAH17235.1 xref: EMBL:BAA76792.2 xref: EMBL:BAD96663.1 xref: EMBL:CAD38700.1 xref: UniProtKB:O14710 xref: UniProtKB:Q53GI8 xref: UniProtKB:Q8NDM4 xref: UniProtKB:Q969Z0 xref: UniProtKB:Q9BUC6 xref: UniProtKB:Q9Y2F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005746 ! TBRG4_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0014320 ! TBRG4_HUMAN-Phosphothreonine65 [Term] id: CCO:B0002031 name: E2F7_HUMAN def: "Transcription factor E2F7" [UniProtKB:Q96AV8] synonym: "E2F-7" EXACT [UniProtKB:Q96AV8] xref: EMBL:AAH16658.1 xref: UniProtKB:A6NC74 xref: UniProtKB:Q96AV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004539 ! E2F7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064915 ! E2F7_HUMAN-Phosphoserine410 [Term] id: CCO:B0002032 name: SKA1_HUMAN def: "Spindle and kinetochore-associated protein 1" [UniProtKB:Q96BD8] xref: EMBL:AAH15706.1 xref: UniProtKB:Q96BD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005619 ! SKA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000388 ! spindle relationship: participates_in CCO:I0005739 ! c18orf24-pldn physical interaction relationship: participates_in CCO:I0005888 ! c14orf48-c18orf24 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002033 name: PINX1_HUMAN def: "Pin2-interacting protein X1" [UniProtKB:Q96BK5] synonym: "Liver-related putative tumor suppressor" EXACT [UniProtKB:Q96BK5] synonym: "Protein 67-11-3" EXACT [UniProtKB:Q96BK5] synonym: "TRF1-interacting protein 1" EXACT [UniProtKB:Q96BK5] xref: EMBL:AAG18009.1 xref: EMBL:AAH15479.1 xref: EMBL:AAH93762.1 xref: EMBL:AAK31790.1 xref: EMBL:AAN31333.1 xref: EMBL:AAP37006.1 xref: EMBL:BAA91263.1 xref: EMBL:CAC51436.1 xref: UniProtKB:Q548A5 xref: UniProtKB:Q7Z7J8 xref: UniProtKB:Q96BK5 xref: UniProtKB:Q96QD7 xref: UniProtKB:Q9HBU7 xref: UniProtKB:Q9NWW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005318 ! PINX1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0008414 ! pafah1b2-pinx1 physical interaction relationship: participates_in CCO:I0008485 ! mpz-pinx1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0002034 name: CCDC5_HUMAN def: "Coiled-coil domain-containing protein 5" [UniProtKB:Q96CS2] synonym: "Enhancer of invasion-cluster" EXACT [UniProtKB:Q96CS2] synonym: "HEI-C" EXACT [UniProtKB:Q96CS2] xref: EMBL:AAH05958.1 xref: EMBL:AAH14003.1 xref: EMBL:AAQ63649.1 xref: EMBL:BAC05036.1 xref: UniProtKB:Q8N837 xref: UniProtKB:Q96CS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004240 ! CCDC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002035 name: CHFR_HUMAN def: "E3 ubiquitin-protein ligase CHFR" [UniProtKB:Q96EP1] synonym: "Checkpoint with forkhead and RING finger domains protein" EXACT [UniProtKB:Q96EP1] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q96EP1] synonym: "RING finger protein 196" EXACT [UniProtKB:Q96EP1] xref: EMBL:AAF91084.1 xref: EMBL:AAH12072.1 xref: EMBL:BAA91817.1 xref: EMBL:BAB55297.1 xref: EMBL:CAB70812.1 xref: UniProtKB:A6NEN5 xref: UniProtKB:Q96EP1 xref: UniProtKB:Q96SL3 xref: UniProtKB:Q9NRT4 xref: UniProtKB:Q9NT32 xref: UniProtKB:Q9NVD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004346 ! CHFR_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008375 ! chfr-eef1g physical interaction relationship: participates_in CCO:I0008450 ! brd4-chfr physical interaction relationship: participates_in CCO:I0008459 ! chfr-gabbr1 physical interaction relationship: participates_in CCO:I0008460 ! chfr-itgae physical interaction relationship: participates_in CCO:I0008461 ! chfr-wdr47 physical interaction relationship: participates_in CCO:P0000038 ! mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011210 ! CHFR_HUMAN-Phosphothreonine130 relationship: transforms_into CCO:B0011211 ! CHFR_HUMAN-Phosphothreonine386 [Term] id: CCO:B0002036 name: MCRS1_HUMAN def: "Microspherule protein 1" [UniProtKB:Q96EZ8] synonym: "58 kDa microspherule protein" EXACT [UniProtKB:Q96EZ8] synonym: "Cell cycle-regulated factor p78" EXACT [UniProtKB:Q96EZ8] synonym: "INO80 complex subunit J" EXACT [UniProtKB:Q96EZ8] synonym: "MCRS2" EXACT [UniProtKB:Q96EZ8] xref: EMBL:AAC52086.1 xref: EMBL:AAC68599.1 xref: EMBL:AAH11794.1 xref: EMBL:AAQ84517.1 xref: UniProtKB:O14742 xref: UniProtKB:O75497 xref: UniProtKB:Q6VN53 xref: UniProtKB:Q96EZ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005044 ! MCRS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005771 ! dvl2-mcrs1 physical interaction relationship: participates_in CCO:I0005869 ! mcrs1-med4 physical interaction relationship: participates_in CCO:I0006008 ! daxx-mcrs1-3 physical interaction relationship: participates_in CCO:I0006009 ! mcrs1-daxx-4 physical interaction relationship: participates_in CCO:I0006010 ! daxx-mcrs1-4 physical interaction relationship: participates_in CCO:I0006272 ! daxx-mcrs1-2 physical interaction relationship: participates_in CCO:I0006273 ! mcrs1-daxx-2 physical interaction relationship: participates_in CCO:I0006274 ! mcrs1-daxx-1 physical interaction relationship: participates_in CCO:I0006275 ! mcrs1-daxx-3 physical interaction relationship: participates_in CCO:I0007332 ! pbx2-mcrs1 physical interaction relationship: participates_in CCO:I0007777 ! mcrs1-ruvbl physical interaction relationship: transforms_into CCO:B0012840 ! MCRS1_HUMAN-Phosphothreonine103 relationship: transforms_into CCO:B0012841 ! MCRS1_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0012842 ! MCRS1_HUMAN-Phosphoserine282 [Term] id: CCO:B0002037 name: DDX11_HUMAN def: "Probable ATP-dependent RNA helicase DDX11" [UniProtKB:Q96FC9] synonym: "CHL1-related protein 1" EXACT [UniProtKB:Q96FC9] synonym: "DEAD/H box protein 11" EXACT [UniProtKB:Q96FC9] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q96FC9] synonym: "hCHLR1" EXACT [UniProtKB:Q96FC9] synonym: "Keratinocyte growth factor-regulated gene 2 protein" EXACT [UniProtKB:Q96FC9] synonym: "KRG-2" EXACT [UniProtKB:Q96FC9] xref: EMBL:AAB06962.1 xref: EMBL:AAB18749.1 xref: EMBL:AAB18750.1 xref: EMBL:AAH50069.1 xref: EMBL:AAH50522.1 xref: EMBL:CAA67895.1 xref: UniProtKB:Q13333 xref: UniProtKB:Q86VQ4 xref: UniProtKB:Q86W62 xref: UniProtKB:Q92498 xref: UniProtKB:Q92770 xref: UniProtKB:Q92998 xref: UniProtKB:Q92999 xref: UniProtKB:Q96FC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004454 ! DDX11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000014 ! S phase of mitotic cell cycle relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0002038 name: CDCA5_HUMAN def: "Sororin" [UniProtKB:Q96FF9] synonym: "Cell division cycle-associated protein 5" EXACT [UniProtKB:Q96FF9] synonym: "p35" EXACT [UniProtKB:Q96FF9] xref: EMBL:AAH11000.1 xref: UniProtKB:Q96FF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004297 ! CDCA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008369 ! cdca5-g22p1 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0000094 ! mitotic metaphase plate congression relationship: participates_in CCO:P0000324 ! interphase of mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011098 ! CDCA5_HUMAN-Phosphothreonine48 relationship: transforms_into CCO:B0011099 ! CDCA5_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0011100 ! CDCA5_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0011101 ! CDCA5_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0048191 ! CDCA5_HUMAN-Phosphothreonine159 relationship: transforms_into CCO:B0064219 ! CDCA5_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0064220 ! CDCA5_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0064221 ! CDCA5_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0064222 ! CDCA5_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0064223 ! CDCA5_HUMAN-Phosphothreonine105 relationship: transforms_into CCO:B0064224 ! CDCA5_HUMAN-Phosphothreonine111 relationship: transforms_into CCO:B0064225 ! CDCA5_HUMAN-Phosphothreonine115 relationship: transforms_into CCO:B0064226 ! CDCA5_HUMAN-Phosphoserine209 [Term] id: CCO:B0002039 name: SIPA1_HUMAN def: "Signal-induced proliferation-associated protein 1" [UniProtKB:Q96FS4] synonym: "GTPase-activating protein Spa-1" EXACT [UniProtKB:Q96FS4] synonym: "p130 SPA-1" EXACT [UniProtKB:Q96FS4] synonym: "Sipa-1" EXACT [UniProtKB:Q96FS4] xref: EMBL:AAC32547.1 xref: EMBL:AAC32559.1 xref: EMBL:AAH10492.1 xref: EMBL:AAI10354.1 xref: EMBL:BAA22197.1 xref: UniProtKB:O14518 xref: UniProtKB:O60484 xref: UniProtKB:O60618 xref: UniProtKB:Q2YD83 xref: UniProtKB:Q96FS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005616 ! SIPA1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006230 ! Rap GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0014063 ! SIPA1_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0048392 ! SIPA1_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0070538 ! SIPA1_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0070539 ! SIPA1_HUMAN-Phosphoserine55 relationship: transforms_into CCO:B0070540 ! SIPA1_HUMAN-Phosphothreonine64 relationship: transforms_into CCO:B0070541 ! SIPA1_HUMAN-Phosphoserine67 [Term] id: CCO:B0002040 name: AURKB_HUMAN def: "Serine/threonine-protein kinase 12" [UniProtKB:Q96GD4] synonym: "AIM-1" EXACT [UniProtKB:Q96GD4] synonym: "Aurora- and Ipl1-like midbody-associated protein 1" EXACT [UniProtKB:Q96GD4] synonym: "Aurora-B" EXACT [UniProtKB:Q96GD4] synonym: "Aurora-related kinase 2" EXACT [UniProtKB:Q96GD4] synonym: "Aurora/IPL1-related kinase 2" EXACT [UniProtKB:Q96GD4] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q96GD4] synonym: "STK-1" EXACT [UniProtKB:Q96GD4] xref: EMBL:AAB65786.1 xref: EMBL:AAC12709.1 xref: EMBL:AAC98891.1 xref: EMBL:AAH00442.3 xref: EMBL:AAH09751.1 xref: EMBL:AAH13300.2 xref: EMBL:AAH80581.1 xref: EMBL:AAV38341.1 xref: EMBL:BAA32136.1 xref: EMBL:BAA82709.1 xref: UniProtKB:O14630 xref: UniProtKB:O60446 xref: UniProtKB:O95083 xref: UniProtKB:Q96DV5 xref: UniProtKB:Q96GD4 xref: UniProtKB:Q9UQ46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004129 ! AURKB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006031 ! sept1-aurkb-5 phosphorylation relationship: participates_in CCO:I0006206 ! sept1-aurkb-2 physical interaction relationship: participates_in CCO:I0006533 ! sept1-aurkb-3 physical interaction relationship: participates_in CCO:I0006731 ! sept1-aurkb-4 physical interaction relationship: participates_in CCO:I0007353 ! tacc1-aurkb-5 physical interaction relationship: participates_in CCO:I0007357 ! sept1-aurkb-1 physical interaction relationship: participates_in CCO:I0007423 ! tacc1-aurkb-4 physical interaction relationship: participates_in CCO:I0008448 ! aurkb-tbl3 physical interaction relationship: participates_in CCO:I0008474 ! flj10415-aurkb physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010722 ! AURKB_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0010723 ! AURKB_HUMAN-Phosphotyrosine12 relationship: transforms_into CCO:B0010724 ! AURKB_HUMAN-Phosphothreonine232 relationship: transforms_into CCO:B0063684 ! AURKB_HUMAN-Phosphothreonine35 [Term] id: CCO:B0002041 name: SENP5_HUMAN def: "Sentrin-specific protease 5" [UniProtKB:Q96HI0] synonym: "EC 3.4.22.-" EXACT [UniProtKB:Q96HI0] synonym: "Sentrin/SUMO-specific protease SENP5" EXACT [UniProtKB:Q96HI0] xref: EMBL:AAH08589.1 xref: EMBL:AAH30705.1 xref: EMBL:AAK69630.1 xref: UniProtKB:Q96HI0 xref: UniProtKB:Q96SA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005579 ! SENP5_human relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002042 name: SGSM3_HUMAN def: "Small G protein signaling modulator 3" [UniProtKB:Q96HU1] synonym: "Merlin-associated protein" EXACT [UniProtKB:Q96HU1] synonym: "Rab-GTPase-activating protein-like protein" EXACT [UniProtKB:Q96HU1] synonym: "RabGAPLP" EXACT [UniProtKB:Q96HU1] synonym: "RUN and TBC1 domain-containing protein 3" EXACT [UniProtKB:Q96HU1] xref: EMBL:AAH08078.1 xref: EMBL:AAQ81879.1 xref: EMBL:BAE02561.1 xref: EMBL:BAF63513.1 xref: EMBL:CAB70773.1 xref: EMBL:CAG30327.1 xref: EMBL:CAQ08933.1 xref: EMBL:EAW60378.1 xref: EMBL:EAW60379.1 xref: UniProtKB:B0QY79 xref: UniProtKB:Q7Z709 xref: UniProtKB:Q96HU1 xref: UniProtKB:Q9NT69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005603 ! SGSM3_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003592 ! Rab GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: participates_in CCO:P0001629 ! regulation of Rab protein signal transduction relationship: participates_in CCO:P0001632 ! Rap protein signal transduction [Term] id: CCO:B0002043 name: NSL1_HUMAN def: "Kinetochore-associated protein NSL1 homolog" [UniProtKB:Q96IY1] xref: EMBL:AAF86877.1 xref: EMBL:AAG44640.1 xref: EMBL:AAH07067.1 xref: EMBL:CAB43260.1 xref: EMBL:CAI17046.1 xref: UniProtKB:Q5SY75 xref: UniProtKB:Q96IY1 xref: UniProtKB:Q9H2M5 xref: UniProtKB:Q9NRN8 xref: UniProtKB:Q9Y415 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005216 ! NSL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013262 ! NSL1_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0013263 ! NSL1_HUMAN-Phosphothreonine242 [Term] id: CCO:B0002044 name: CK5P3_HUMAN def: "CDK5 regulatory subunit-associated protein 3" [UniProtKB:Q96JB5] synonym: "CDK5 activator-binding protein C53" EXACT [UniProtKB:Q96JB5] synonym: "Protein HSF-27" EXACT [UniProtKB:Q96JB5] xref: EMBL:AAG17225.1 xref: EMBL:AAG39277.1 xref: EMBL:AAH09957.1 xref: EMBL:AAH72435.1 xref: EMBL:AAK69655.1 xref: EMBL:BAB14657.1 xref: EMBL:BAB93496.1 xref: EMBL:BAD97107.1 xref: UniProtKB:Q53FA2 xref: UniProtKB:Q96JB5 xref: UniProtKB:Q9H3F8 xref: UniProtKB:Q9H8G0 xref: UniProtKB:Q9HBR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004360 ! CDK5RAP3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005717 ! neuronal Cdc2-like kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006575 ! disc1-cdk5rap3-1 physical interaction relationship: participates_in CCO:I0006576 ! disc1-cdk5rap3-2 physical interaction relationship: participates_in CCO:I0006799 ! disc1-cdk5rap3 physical interaction relationship: participates_in CCO:I0008370 ! cdk5rap3-crmp1 physical interaction relationship: participates_in CCO:I0008455 ! cdk5rap3-srprb physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation [Term] id: CCO:B0002045 name: TOPK_HUMAN def: "Lymphokine-activated killer T-cell-originated protein kinase" [UniProtKB:Q96KB5] synonym: "Cancer/testis antigen 84" EXACT [UniProtKB:Q96KB5] synonym: "CT84" EXACT [UniProtKB:Q96KB5] synonym: "EC 2.7.12.2" EXACT [UniProtKB:Q96KB5] synonym: "MAPKK-like protein kinase" EXACT [UniProtKB:Q96KB5] synonym: "Nori-3" EXACT [UniProtKB:Q96KB5] synonym: "PDZ-binding kinase" EXACT [UniProtKB:Q96KB5] synonym: "Spermatogenesis-related protein kinase" EXACT [UniProtKB:Q96KB5] synonym: "SPK" EXACT [UniProtKB:Q96KB5] synonym: "T-LAK cell-originated protein kinase" EXACT [UniProtKB:Q96KB5] xref: EMBL:AAF69107.1 xref: EMBL:AAF71521.1 xref: EMBL:AAH15191.1 xref: EMBL:BAA99576.1 xref: EMBL:BAA99577.1 xref: EMBL:BAB55019.1 xref: UniProtKB:Q96KB5 xref: UniProtKB:Q9NPD9 xref: UniProtKB:Q9NYL7 xref: UniProtKB:Q9NZK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005813 ! PBK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005924 ! pbk-trim37 physical interaction relationship: participates_in CCO:I0006965 ! araf-pbk physical interaction relationship: participates_in CCO:I0007554 ! araf-pbk-1 physical interaction relationship: participates_in CCO:I0007555 ! araf-pbk-2 physical interaction relationship: participates_in CCO:I0007860 ! raf1-pbk physical interaction relationship: participates_in CCO:I0008176 ! pbk-gps2 physical interaction relationship: participates_in CCO:I0008342 ! pbk-kiaa1377 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0014448 ! TOPK_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0014449 ! TOPK_HUMAN-Phosphothreonine200 relationship: transforms_into CCO:B0071454 ! TOPK_HUMAN-Phosphothreonine24 relationship: transforms_into CCO:B0071455 ! TOPK_HUMAN-Phosphoserine32 [Term] id: CCO:B0002046 name: ASPP1_HUMAN def: "Apoptosis-stimulating of p53 protein 1" [UniProtKB:Q96KQ4] synonym: "Protein phosphatase 1 regulatory subunit 13B" EXACT [UniProtKB:Q96KQ4] xref: EMBL:BAA34491.1 xref: EMBL:CAC83011.2 xref: UniProtKB:O94870 xref: UniProtKB:Q96KQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004109 ! PPP1R13B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006599 ! cdc5l-ppp1r13b physical interaction relationship: participates_in CCO:I0006600 ! tnik-ppp1r13b physical interaction relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0010628 ! ASPP1_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0010629 ! ASPP1_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0010630 ! ASPP1_HUMAN-Phosphoserine671 relationship: transforms_into CCO:B0063630 ! ASPP1_HUMAN-Phosphoserine681 [Term] id: CCO:B0002047 name: LMLN_HUMAN def: "Leishmanolysin-like peptidase" [UniProtKB:Q96KR4] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q96KR4] synonym: "Invadolysin" EXACT [UniProtKB:Q96KR4] xref: EMBL:CAC42882.1 xref: EMBL:CAC42883.1 xref: UniProtKB:Q96KR4 xref: UniProtKB:Q96KR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004984 ! LMLN_human relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002048 name: Q96LE1_HUMAN def: "Cyclin-dependent kinase inhibitor isoform" [UniProtKB:Q96LE1] xref: EMBL:AAG15411.1 xref: UniProtKB:Q96LE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0002049 name: HEXI2_HUMAN def: "Protein HEXIM2" [UniProtKB:Q96MH2] synonym: "Hexamethylene bis-acetamide-inducible protein 2" EXACT [UniProtKB:Q96MH2] xref: EMBL:AAH03531.1 xref: EMBL:AAH12474.1 xref: EMBL:AAH25970.1 xref: EMBL:AAT06733.1 xref: EMBL:BAB71319.1 xref: EMBL:EAW51541.1 xref: UniProtKB:Q96MH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004802 ! HEXIM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012182 ! HEXI2_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0012183 ! HEXI2_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0048275 ! HEXI2_HUMAN-Phosphothreonine46 relationship: transforms_into CCO:B0066798 ! HEXI2_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0066799 ! HEXI2_HUMAN-Phosphothreonine32 relationship: transforms_into CCO:B0066800 ! HEXI2_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0066801 ! HEXI2_HUMAN-Phosphoserine81 [Term] id: CCO:B0002050 name: Q96MY5_HUMAN def: "Septin" [UniProtKB:Q96MY5] xref: EMBL:BAB71133.1 xref: EMBL:EAX03032.1 xref: UniProtKB:Q96MY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006040 ! hCG_2002594_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002051 name: ZN830_HUMAN def: "Zinc finger protein 830" [UniProtKB:Q96NB3] synonym: "Coiled-coil domain-containing protein 16" EXACT [UniProtKB:Q96NB3] xref: EMBL:AAH02913.2 xref: EMBL:AAH09044.1 xref: EMBL:AAH11584.1 xref: EMBL:BAB70992.1 xref: UniProtKB:Q96F60 xref: UniProtKB:Q96GZ5 xref: UniProtKB:Q96NB3 xref: UniProtKB:Q9BU38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014371 ! ZNF830_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0048427 ! ZN830_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0048428 ! ZN830_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0048429 ! ZN830_HUMAN-Phosphoserine362 [Term] id: CCO:B0002052 name: CEND2_HUMAN def: "Centaurin-delta-2" [UniProtKB:Q96P48] synonym: "Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2" EXACT [UniProtKB:Q96P48] synonym: "Cnt-d2" EXACT [UniProtKB:Q96P48] xref: EMBL:AAH08315.1 xref: EMBL:AAH56401.1 xref: EMBL:AAL04167.1 xref: EMBL:AAL12169.1 xref: EMBL:BAA34502.2 xref: EMBL:BAD92710.1 xref: EMBL:CAF21317.1 xref: UniProtKB:O94879 xref: UniProtKB:Q4LDD5 xref: UniProtKB:Q59FI7 xref: UniProtKB:Q6PHS3 xref: UniProtKB:Q8WU51 xref: UniProtKB:Q96HP6 xref: UniProtKB:Q96L71 xref: UniProtKB:Q96P48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004321 ! CENTD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007575 ! g22p1-centd2-1 physical interaction relationship: participates_in CCO:I0008066 ! arih2-centd2 physical interaction relationship: participates_in CCO:I0008232 ! fgfr3-centd2 physical interaction relationship: participates_in CCO:I0008358 ! arpc3-centd2 physical interaction relationship: participates_in CCO:I0008373 ! centd2-g22p1 physical interaction relationship: participates_in CCO:P0000161 ! actin filament reorganization during cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: participates_in CCO:P0002157 ! positive regulation of Cdc42 GTPase activity relationship: participates_in CCO:P0003071 ! regulation of cell motility relationship: participates_in CCO:P0003103 ! positive regulation of filopodium formation relationship: participates_in CCO:P0003109 ! negative regulation of stress fiber formation relationship: transforms_into CCO:B0011133 ! CEND2_HUMAN-Phosphothreonine114 relationship: transforms_into CCO:B0011134 ! CEND2_HUMAN-Phosphotyrosine497 relationship: transforms_into CCO:B0048193 ! CEND2_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0064259 ! CEND2_HUMAN-Phosphotyrosine191 relationship: transforms_into CCO:B0064260 ! CEND2_HUMAN-Phosphoserine1195 [Term] id: CCO:B0002053 name: MACF4_HUMAN def: "Microtubule-actin cross-linking factor 1, isoform 4" [UniProtKB:Q96PK2] xref: EMBL:AAL09459.1 xref: EMBL:AAL38997.1 xref: UniProtKB:Q8WXY1 xref: UniProtKB:Q96PK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005012 ! MACF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0012752 ! MACF4_HUMAN-Phosphoserine2576 relationship: transforms_into CCO:B0012753 ! MACF4_HUMAN-Phosphoserine2577 relationship: transforms_into CCO:B0012754 ! MACF4_HUMAN-Phosphoserine2579 relationship: transforms_into CCO:B0012755 ! MACF4_HUMAN-Phosphothreonine5627 relationship: transforms_into CCO:B0012756 ! MACF4_HUMAN-Phosphothreonine5823 relationship: transforms_into CCO:B0048314 ! MACF4_HUMAN-Phosphotyrosine1554 relationship: transforms_into CCO:B0067835 ! MACF4_HUMAN-Phosphoserine2362 relationship: transforms_into CCO:B0067836 ! MACF4_HUMAN-Phosphoserine2930 relationship: transforms_into CCO:B0067837 ! MACF4_HUMAN-Phosphoserine2931 relationship: transforms_into CCO:B0067838 ! MACF4_HUMAN-Phosphoserine2956 relationship: transforms_into CCO:B0067839 ! MACF4_HUMAN-Phosphoserine5797 relationship: transforms_into CCO:B0067840 ! MACF4_HUMAN-Phosphoserine5801 relationship: transforms_into CCO:B0067841 ! MACF4_HUMAN-Phosphothreonine5804 relationship: transforms_into CCO:B0067842 ! MACF4_HUMAN-Phosphoserine5842 [Term] id: CCO:B0002054 name: UHRF2_HUMAN def: "E3 ubiquitin-protein ligase UHRF2" [UniProtKB:Q96PU4] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q96PU4] synonym: "Np95-like RING finger protein" EXACT [UniProtKB:Q96PU4] synonym: "Np95/ICBP90-like RING finger protein" EXACT [UniProtKB:Q96PU4] synonym: "Nuclear zinc finger protein Np97" EXACT [UniProtKB:Q96PU4] synonym: "RING finger protein 107" EXACT [UniProtKB:Q96PU4] synonym: "Ubiquitin-like PHD and RING finger domain-containing protein 2" EXACT [UniProtKB:Q96PU4] synonym: "Ubiquitin-like-containing PHD and RING finger domains protein 2" EXACT [UniProtKB:Q96PU4] xref: EMBL:AAH28397.1 xref: EMBL:AAM33799.1 xref: EMBL:BAB68317.1 xref: EMBL:CAH56383.1 xref: EMBL:CAH74119.1 xref: EMBL:CAH74120.1 xref: EMBL:CAI13293.1 xref: EMBL:CAI13295.1 xref: UniProtKB:Q5VYR1 xref: UniProtKB:Q5VYR3 xref: UniProtKB:Q659C8 xref: UniProtKB:Q8TAG7 xref: UniProtKB:Q96PU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005880 ! UHRF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006027 ! uhrf2-cdk2-1 physical interaction relationship: participates_in CCO:I0006028 ! uhrf2-cdk2-3 physical interaction relationship: participates_in CCO:I0007120 ! uhrf2-cdk2-4 direct interaction relationship: participates_in CCO:I0007419 ! uhrf2-cdk2-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000346 ! regulation of cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0071718 ! UHRF2_HUMAN-Phosphoserine667 [Term] id: CCO:B0002055 name: NEK1_HUMAN def: "Serine/threonine-protein kinase Nek1" [UniProtKB:Q96PY6] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q96PY6] synonym: "NimA-related protein kinase 1" EXACT [UniProtKB:Q96PY6] synonym: "Renal carcinoma antigen NY-REN-55" EXACT [UniProtKB:Q96PY6] xref: EMBL:AAD42879.1 xref: EMBL:AAH15147.1 xref: EMBL:AAH37790.1 xref: EMBL:AAI14492.1 xref: EMBL:BAB15207.1 xref: EMBL:BAB55209.1 xref: EMBL:BAB67794.1 xref: EMBL:CAI45943.1 xref: UniProtKB:Q05DG5 xref: UniProtKB:Q14CB7 xref: UniProtKB:Q5H9T1 xref: UniProtKB:Q6PIB8 xref: UniProtKB:Q96PY6 xref: UniProtKB:Q96SS2 xref: UniProtKB:Q9H6P7 xref: UniProtKB:Q9Y594 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005175 ! NEK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006164 ! nek1-fez1-2 physical interaction relationship: participates_in CCO:I0006165 ! nek1-fez2-1 physical interaction relationship: participates_in CCO:I0006481 ! exosc4-nek1 physical interaction relationship: participates_in CCO:I0007235 ! nek1-fez2-2 physical interaction relationship: participates_in CCO:I0007268 ! nek1-fez1-3 physical interaction relationship: participates_in CCO:I0007269 ! nek1-ywhah-1 physical interaction relationship: participates_in CCO:I0007270 ! nek1-xh2-1 physical interaction relationship: participates_in CCO:I0007271 ! nek1-mre11-1 physical interaction relationship: participates_in CCO:I0007272 ! nek1-tp53bp1-1 physical interaction relationship: participates_in CCO:I0007273 ! nek1-kif3a physical interaction relationship: participates_in CCO:I0007274 ! nek1-ppp2r5d-1 physical interaction relationship: participates_in CCO:I0007275 ! nek1-tsc2-1 physical interaction relationship: participates_in CCO:I0007276 ! nek1-ctnnal1-1 physical interaction relationship: participates_in CCO:I0007277 ! nek1-tsc2-2 physical interaction relationship: participates_in CCO:I0007278 ! nek1-tsc2-3 physical interaction relationship: participates_in CCO:I0007279 ! nek1-nek1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013145 ! NEK1_HUMAN-Phosphothreonine162 relationship: transforms_into CCO:B0013146 ! NEK1_HUMAN-Phosphoserine664 relationship: transforms_into CCO:B0013147 ! NEK1_HUMAN-Phosphoserine1126 [Term] id: CCO:B0002056 name: MPPH1_HUMAN def: "M-phase phosphoprotein 1" [UniProtKB:Q96Q89] synonym: "Cancer/testis antigen 90" EXACT [UniProtKB:Q96Q89] synonym: "CT90" EXACT [UniProtKB:Q96Q89] synonym: "Kinesin-related motor interacting with PIN1" EXACT [UniProtKB:Q96Q89] synonym: "MPP1" EXACT [UniProtKB:Q96Q89] xref: EMBL:AAB88727.1 xref: EMBL:AAC37542.1 xref: EMBL:AAH12585.1 xref: EMBL:AAH46134.1 xref: EMBL:AAH58913.1 xref: EMBL:AAH93089.1 xref: EMBL:AAI08689.1 xref: EMBL:AAP40330.1 xref: EMBL:AAP40331.1 xref: EMBL:AAW65984.1 xref: EMBL:BAB15043.1 xref: EMBL:BAB15194.1 xref: EMBL:BAB20417.1 xref: EMBL:BAB69456.1 xref: EMBL:CAB55962.1 xref: EMBL:CAB70720.1 xref: EMBL:CAI12885.1 xref: EMBL:CAI12886.1 xref: EMBL:CAI12887.1 xref: EMBL:CAI16829.1 xref: EMBL:CAI16830.1 xref: EMBL:CAI16831.1 xref: EMBL:CAI16832.1 xref: UniProtKB:O43277 xref: UniProtKB:Q09471 xref: UniProtKB:Q2KQ73 xref: UniProtKB:Q32NE1 xref: UniProtKB:Q561V3 xref: UniProtKB:Q58EX8 xref: UniProtKB:Q5T9M8 xref: UniProtKB:Q5T9M9 xref: UniProtKB:Q5T9N0 xref: UniProtKB:Q5T9N1 xref: UniProtKB:Q7KZ68 xref: UniProtKB:Q7Z5E0 xref: UniProtKB:Q7Z5E1 xref: UniProtKB:Q7Z6M9 xref: UniProtKB:Q86X82 xref: UniProtKB:Q96Q89 xref: UniProtKB:Q9H3R8 xref: UniProtKB:Q9H6Q9 xref: UniProtKB:Q9H755 xref: UniProtKB:Q9NTC1 xref: UniProtKB:Q9UFR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005123 ! MPHOSPH1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0007999 ! WW domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013001 ! MPPH1_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0013002 ! MPPH1_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0013003 ! MPPH1_HUMAN-Phosphoserine321 relationship: transforms_into CCO:B0013004 ! MPPH1_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0013005 ! MPPH1_HUMAN-Phosphoserine488 relationship: transforms_into CCO:B0013006 ! MPPH1_HUMAN-Phosphoserine999 relationship: transforms_into CCO:B0013007 ! MPPH1_HUMAN-Phosphoserine1071 relationship: transforms_into CCO:B0013008 ! MPPH1_HUMAN-Phosphoserine1072 relationship: transforms_into CCO:B0013009 ! MPPH1_HUMAN-Phosphothreonine1644 [Term] id: CCO:B0002057 name: Q96Q97_HUMAN def: "Bradeion alpha" [UniProtKB:Q96Q97] xref: EMBL:BAB70694.1 xref: UniProtKB:Q96Q97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006042 ! CE5B3 alpha_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002058 name: SPAG5_HUMAN def: "Sperm-associated antigen 5" [UniProtKB:Q96R06] synonym: "Astrin" EXACT [UniProtKB:Q96R06] synonym: "Deepest" EXACT [UniProtKB:Q96R06] synonym: "MAP126" EXACT [UniProtKB:Q96R06] synonym: "Mitotic spindle-associated protein p126" EXACT [UniProtKB:Q96R06] xref: EMBL:AAD02813.1 xref: EMBL:AAH00322.1 xref: EMBL:AAK91712.1 xref: EMBL:AAL06396.2 xref: EMBL:CAB59275.1 xref: EMBL:CAB70827.1 xref: UniProtKB:O95213 xref: UniProtKB:Q96R06 xref: UniProtKB:Q9BWE8 xref: UniProtKB:Q9NT17 xref: UniProtKB:Q9UFE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005652 ! SPAG5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007618 ! atn1-spag5 physical interaction relationship: participates_in CCO:I0008321 ! snapap-spag5 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000385 ! spindle organization and biogenesis relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014158 ! SPAG5_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0014159 ! SPAG5_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0014160 ! SPAG5_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0014161 ! SPAG5_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0014162 ! SPAG5_HUMAN-Phosphothreonine111 relationship: transforms_into CCO:B0014163 ! SPAG5_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0014164 ! SPAG5_HUMAN-Phosphoserine249 relationship: transforms_into CCO:B0014165 ! SPAG5_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0014166 ! SPAG5_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0014167 ! SPAG5_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0014168 ! SPAG5_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0014169 ! SPAG5_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0014170 ! SPAG5_HUMAN-Phosphothreonine377 relationship: transforms_into CCO:B0014171 ! SPAG5_HUMAN-Phosphothreonine389 relationship: transforms_into CCO:B0014172 ! SPAG5_HUMAN-Phosphoserine401 relationship: transforms_into CCO:B0014173 ! SPAG5_HUMAN-Phosphothreonine937 relationship: transforms_into CCO:B0070786 ! SPAG5_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0070787 ! SPAG5_HUMAN-Phosphothreonine50 relationship: transforms_into CCO:B0070788 ! SPAG5_HUMAN-Phosphoserine65 [Term] id: CCO:B0002059 name: LAP2_HUMAN def: "Protein LAP2" [UniProtKB:Q96RT1] synonym: "Densin-180-like protein" EXACT [UniProtKB:Q96RT1] synonym: "Erbb2-interacting protein" EXACT [UniProtKB:Q96RT1] synonym: "Erbin" EXACT [UniProtKB:Q96RT1] xref: EMBL:AAF77048.1 xref: EMBL:AAH50692.1 xref: EMBL:AAK69431.1 xref: EMBL:BAA86539.2 xref: EMBL:BAA91538.1 xref: UniProtKB:Q86W38 xref: UniProtKB:Q96RT1 xref: UniProtKB:Q9NR18 xref: UniProtKB:Q9NW48 xref: UniProtKB:Q9ULJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004970 ! ERBB2IP_human relationship: has_function CCO:F0001477 ! ErbB-2 class receptor binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000938 ! hemidesmosome relationship: participates_in CCO:I0006766 ! shoc2-erbb2ip-2 physical interaction relationship: participates_in CCO:I0007382 ! shoc2-erbb2ip physical interaction relationship: participates_in CCO:I0007383 ! shoc2-erbb2ip-3 physical interaction relationship: participates_in CCO:I0007466 ! shoc2-erbb2ip-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0012659 ! LAP2_HUMAN-Phosphoserine440 relationship: transforms_into CCO:B0012660 ! LAP2_HUMAN-Phosphotyrosine483 relationship: transforms_into CCO:B0012661 ! LAP2_HUMAN-Phosphothreonine485 relationship: transforms_into CCO:B0012662 ! LAP2_HUMAN-Phosphotyrosine487 relationship: transforms_into CCO:B0012663 ! LAP2_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0012664 ! LAP2_HUMAN-Phosphoserine602 relationship: transforms_into CCO:B0012665 ! LAP2_HUMAN-Phosphoserine603 relationship: transforms_into CCO:B0012666 ! LAP2_HUMAN-Phosphotyrosine733 relationship: transforms_into CCO:B0012667 ! LAP2_HUMAN-Phosphothreonine853 relationship: transforms_into CCO:B0012668 ! LAP2_HUMAN-Phosphoserine857 relationship: transforms_into CCO:B0012669 ! LAP2_HUMAN-Phosphothreonine917 relationship: transforms_into CCO:B0012670 ! LAP2_HUMAN-Phosphotyrosine920 relationship: transforms_into CCO:B0012671 ! LAP2_HUMAN-Phosphotyrosine972 relationship: transforms_into CCO:B0012672 ! LAP2_HUMAN-Phosphotyrosine981 relationship: transforms_into CCO:B0012673 ! LAP2_HUMAN-Phosphotyrosine1104 relationship: transforms_into CCO:B0012674 ! LAP2_HUMAN-Phosphotyrosine1107 relationship: transforms_into CCO:B0012675 ! LAP2_HUMAN-Phosphotyrosine1132 relationship: transforms_into CCO:B0012676 ! LAP2_HUMAN-Phosphoserine1271 relationship: transforms_into CCO:B0048309 ! LAP2_HUMAN-Phosphotyrosine1293 relationship: transforms_into CCO:B0067536 ! LAP2_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0067537 ! LAP2_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0067538 ! LAP2_HUMAN-Phosphoserine1060 relationship: transforms_into CCO:B0067539 ! LAP2_HUMAN-Phosphoserine1286 [Term] id: CCO:B0002060 name: NEB2_HUMAN def: "Neurabin-2" [UniProtKB:Q96SB3] synonym: "Neurabin-II" EXACT [UniProtKB:Q96SB3] synonym: "Protein phosphatase 1 regulatory subunit 9B" EXACT [UniProtKB:Q96SB3] synonym: "Spinophilin" EXACT [UniProtKB:Q96SB3] xref: EMBL:CAC37685.1 xref: EMBL:CAD28455.2 xref: UniProtKB:Q8TCR9 xref: UniProtKB:Q96SB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005171 ! PPP1R9B_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001751 ! protein phosphatase 1 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000030 ! protein phosphatase type 1 complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: participates_in CCO:P0000468 ! regulation of cell growth by extracellular stimulus relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: transforms_into CCO:B0013139 ! NEB2_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0013140 ! NEB2_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0013141 ! NEB2_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0013142 ! NEB2_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0013143 ! NEB2_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0013144 ! NEB2_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0068557 ! NEB2_HUMAN-Phosphothreonine205 [Term] id: CCO:B0002061 name: SRPK1_HUMAN def: "Serine/threonine-protein kinase SRPK1" [UniProtKB:Q96SB4] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q96SB4] synonym: "Serine/arginine-rich protein-specific kinase 1" EXACT [UniProtKB:Q96SB4] synonym: "SFRS protein kinase 1" EXACT [UniProtKB:Q96SB4] synonym: "SR-protein-specific kinase 1" EXACT [UniProtKB:Q96SB4] xref: EMBL:AAA20530.1 xref: EMBL:AAH38292.1 xref: EMBL:CAC39299.1 xref: EMBL:CAI20544.1 xref: EMBL:CAI20545.1 xref: UniProtKB:Q12890 xref: UniProtKB:Q5R364 xref: UniProtKB:Q5R365 xref: UniProtKB:Q8IY12 xref: UniProtKB:Q96SB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005671 ! SRPK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006306 ! srpk1-sfrs1-1 physical interaction relationship: participates_in CCO:I0007093 ! srpk1-top2a-1 physical interaction relationship: participates_in CCO:I0007100 ! srpk1-sfrs1-2 physical interaction relationship: participates_in CCO:I0007250 ! srpk1-top2a-2 physical interaction relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002925 ! regulation of mRNA processing relationship: transforms_into CCO:B0070925 ! SRPK1_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0070926 ! SRPK1_HUMAN-Phosphoserine309 relationship: transforms_into CCO:B0070927 ! SRPK1_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0070928 ! SRPK1_HUMAN-Phosphoserine555 [Term] id: CCO:B0002062 name: CK5P1_HUMAN def: "CDK5 regulatory subunit-associated protein 1" [UniProtKB:Q96SZ6] synonym: "CDK5 activator-binding protein C42" EXACT [UniProtKB:Q96SZ6] xref: EMBL:AAD34147.1 xref: EMBL:AAF29131.1 xref: EMBL:AAH01215.1 xref: EMBL:AAH50706.1 xref: EMBL:BAB14760.1 xref: EMBL:BAB55120.1 xref: EMBL:CAI19393.1 xref: UniProtKB:Q5QP47 xref: UniProtKB:Q96SZ6 xref: UniProtKB:Q9BVG6 xref: UniProtKB:Q9BWZ5 xref: UniProtKB:Q9H859 xref: UniProtKB:Q9NZZ9 xref: UniProtKB:Q9Y3F0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004358 ! CDK5RAP1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005717 ! neuronal Cdc2-like kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008141 ! 4 iron, 4 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006482 ! exosc5-cdk5rap1 physical interaction relationship: participates_in CCO:I0006484 ! exosc3-cdk5rap1 physical interaction relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation [Term] id: CCO:B0002063 name: UHRF1_HUMAN def: "E3 ubiquitin-protein ligase UHRF1" [UniProtKB:Q96T88] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q96T88] synonym: "HuNp95" EXACT [UniProtKB:Q96T88] synonym: "Inverted CCAAT box-binding protein of 90 kDa" EXACT [UniProtKB:Q96T88] synonym: "Nuclear protein 95" EXACT [UniProtKB:Q96T88] synonym: "Nuclear zinc finger protein Np95" EXACT [UniProtKB:Q96T88] synonym: "RING finger protein 106" EXACT [UniProtKB:Q96T88] synonym: "Transcription factor ICBP90" EXACT [UniProtKB:Q96T88] synonym: "Ubiquitin-like PHD and RING finger domain-containing protein 1" EXACT [UniProtKB:Q96T88] synonym: "Ubiquitin-like-containing PHD and RING finger domains protein 1" EXACT [UniProtKB:Q96T88] xref: EMBL:AAF28469.1 xref: EMBL:AAF64067.1 xref: EMBL:AAK55744.1 xref: EMBL:AAV40831.1 xref: EMBL:BAB15177.1 xref: EMBL:BAC20576.1 xref: UniProtKB:Q8J022 xref: UniProtKB:Q96T88 xref: UniProtKB:Q9H6S6 xref: UniProtKB:Q9P115 xref: UniProtKB:Q9P1U7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005879 ! UHRF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0014577 ! UHRF1_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0014578 ! UHRF1_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0014579 ! UHRF1_HUMAN-Phosphoserine639 relationship: transforms_into CCO:B0071715 ! UHRF1_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0071716 ! UHRF1_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0071717 ! UHRF1_HUMAN-Phosphoserine707 [Term] id: CCO:B0002064 name: GML_HUMAN def: "Glycosyl-phosphatidylinositol-anchored molecule-like protein precursor" [UniProtKB:Q99445] xref: EMBL:AAH74930.1 xref: EMBL:AAI26337.1 xref: EMBL:AAI26339.1 xref: EMBL:BAA12300.1 xref: EMBL:BAA19961.1 xref: UniProtKB:A0AVF6 xref: UniProtKB:O00686 xref: UniProtKB:O00731 xref: UniProtKB:Q99445 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004707 ! GML_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000065 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0002065 name: CDC5L_HUMAN def: "Cell division cycle 5-like protein" [UniProtKB:Q99459] synonym: "Cdc5-like protein" EXACT [UniProtKB:Q99459] synonym: "Pombe cdc5-related protein" EXACT [UniProtKB:Q99459] xref: EMBL:AAB61210.1 xref: EMBL:AAH01568.1 xref: EMBL:AAR89913.1 xref: EMBL:BAA20885.1 xref: EMBL:BAA24862.2 xref: EMBL:CAI20149.1 xref: EMBL:CAI40750.1 xref: UniProtKB:Q76N46 xref: UniProtKB:Q99459 xref: UniProtKB:Q99974 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004291 ! CDC5L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0006076 ! orc1l-hscdc5 direct interaction relationship: participates_in CCO:I0006094 ! mcm3-hscdc5 direct interaction relationship: participates_in CCO:I0006097 ! orc2l-hscdc5 direct interaction relationship: participates_in CCO:I0006099 ! mcm4-hscdc5 direct interaction relationship: participates_in CCO:I0006101 ! mcm10-hscdc5 direct interaction relationship: participates_in CCO:I0006147 ! cdkn1a-hscdc5 direct interaction relationship: participates_in CCO:I0006568 ! cdc5l-akap9 physical interaction relationship: participates_in CCO:I0006569 ! cdc5l-aof2 physical interaction relationship: participates_in CCO:I0006572 ! disc1-cdc5l physical interaction relationship: participates_in CCO:I0006573 ! disc1-cdc5l-1 physical interaction relationship: participates_in CCO:I0006577 ! cdc5l-crnkl1 physical interaction relationship: participates_in CCO:I0006582 ! cdc5l-hook1 physical interaction relationship: participates_in CCO:I0006583 ! cdc5l-kiaa0182 physical interaction relationship: participates_in CCO:I0006584 ! cdc5l-kiaa0240 physical interaction relationship: participates_in CCO:I0006585 ! cdc5l-znf451 physical interaction relationship: participates_in CCO:I0006586 ! cdc5l-kif3c physical interaction relationship: participates_in CCO:I0006587 ! cdc5l-kif5b physical interaction relationship: participates_in CCO:I0006588 ! cdc5l-kiaa1267 physical interaction relationship: participates_in CCO:I0006595 ! cdc5l-myt1l physical interaction relationship: participates_in CCO:I0006598 ! cdc5l-ppfia2 physical interaction relationship: participates_in CCO:I0006599 ! cdc5l-ppp1r13b physical interaction relationship: participates_in CCO:I0006603 ! cdc5l-sptbn1 physical interaction relationship: participates_in CCO:I0006605 ! cdc5l-ywhaz physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0011084 ! CDC5L_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0011085 ! CDC5L_HUMAN-Phosphothreonine385 relationship: transforms_into CCO:B0011086 ! CDC5L_HUMAN-Phosphothreonine396 relationship: transforms_into CCO:B0048185 ! CDC5L_HUMAN-Phosphothreonine430 relationship: transforms_into CCO:B0048186 ! CDC5L_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0048187 ! CDC5L_HUMAN-Phosphothreonine438 relationship: transforms_into CCO:B0048188 ! CDC5L_HUMAN-Phosphothreonine442 relationship: transforms_into CCO:B0064192 ! CDC5L_HUMAN-Phosphothreonine227 relationship: transforms_into CCO:B0064193 ! CDC5L_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0064194 ! CDC5L_HUMAN-Phosphothreonine377 relationship: transforms_into CCO:B0064195 ! CDC5L_HUMAN-Phosphothreonine415 relationship: transforms_into CCO:B0064196 ! CDC5L_HUMAN-Phosphothreonine424 relationship: transforms_into CCO:B0064197 ! CDC5L_HUMAN-Phosphothreonine429 [Term] id: CCO:B0002066 name: PSMD1_HUMAN def: "26S proteasome non-ATPase regulatory subunit 1" [UniProtKB:Q99460] synonym: "26S proteasome regulatory subunit RPN2" EXACT [UniProtKB:Q99460] synonym: "26S proteasome regulatory subunit S1" EXACT [UniProtKB:Q99460] synonym: "26S proteasome subunit p112" EXACT [UniProtKB:Q99460] xref: EMBL:AAH01053.1 xref: EMBL:AAH14013.1 xref: EMBL:AAH39845.1 xref: EMBL:AAH47897.1 xref: EMBL:AAH64398.1 xref: EMBL:AAH73833.1 xref: EMBL:AAH94720.1 xref: EMBL:AAI12345.1 xref: EMBL:AAI14435.1 xref: EMBL:AAX93127.1 xref: EMBL:BAA07918.1 xref: UniProtKB:Q24JU0 xref: UniProtKB:Q53TI2 xref: UniProtKB:Q6GMU5 xref: UniProtKB:Q6P2P4 xref: UniProtKB:Q6PJM7 xref: UniProtKB:Q6PKG9 xref: UniProtKB:Q86VU1 xref: UniProtKB:Q8IV79 xref: UniProtKB:Q99460 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005390 ! PSMD1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002079 ! proteasome regulatory particle relationship: participates_in CCO:I0006428 ! traf6-psmd1 physical interaction relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0013627 ! PSMD1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0013628 ! PSMD1_HUMAN-Phosphotyrosine49 relationship: transforms_into CCO:B0013629 ! PSMD1_HUMAN-Phosphothreonine273 relationship: transforms_into CCO:B0013630 ! PSMD1_HUMAN-Phosphothreonine311 relationship: transforms_into CCO:B0013631 ! PSMD1_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0069578 ! PSMD1_HUMAN-Phosphoserine296 [Term] id: CCO:B0002067 name: GA2L1_HUMAN def: "GAS2-like protein 1" [UniProtKB:Q99501] synonym: "GAS2-related protein on chromosome 22" EXACT [UniProtKB:Q99501] synonym: "Growth arrest-specific protein 2-like 1" EXACT [UniProtKB:Q99501] xref: EMBL:AAH01782.1 xref: EMBL:AAH07624.1 xref: EMBL:AAH11047.1 xref: EMBL:BAD97322.1 xref: EMBL:CAA69174.1 xref: EMBL:CAA69176.1 xref: UniProtKB:Q53EN7 xref: UniProtKB:Q92640 xref: UniProtKB:Q99501 xref: UniProtKB:Q9BUY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004671 ! GAS2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0011916 ! GA2L1_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0041137 ! GA2L1_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0041138 ! GA2L1_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0066342 ! GA2L1_HUMAN-Phosphothreonine193 relationship: transforms_into CCO:B0066343 ! GA2L1_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0066344 ! GA2L1_HUMAN-Phosphothreonine391 relationship: transforms_into CCO:B0066345 ! GA2L1_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0066346 ! GA2L1_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0066347 ! GA2L1_HUMAN-Phosphoserine438 relationship: transforms_into CCO:B0066348 ! GA2L1_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0066349 ! GA2L1_HUMAN-Phosphoserine490 relationship: transforms_into CCO:B0066350 ! GA2L1_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0066351 ! GA2L1_HUMAN-Phosphothreonine498 [Term] id: CCO:B0002068 name: Q99539_HUMAN def: "X-1 protein" [UniProtKB:Q99539] xref: EMBL:CAA66919.1 xref: UniProtKB:Q99539 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006044 ! X-1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000039 ! M phase [Term] id: CCO:B0002069 name: Q99540_HUMAN def: "Ligase-like protein" [UniProtKB:Q99540] xref: EMBL:CAA66920.1 xref: UniProtKB:Q99540 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000415 ! DNA ligase (NAD+) activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000039 ! M phase relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0002070 name: ZWIA_HUMAN xref: UniProtKB:Q99546 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000272 ! molecular_function relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002071 name: MPH6_HUMAN def: "M-phase phosphoprotein 6" [UniProtKB:Q99547] xref: EMBL:AAH05242.1 xref: EMBL:AAH11020.1 xref: EMBL:AAH31017.1 xref: EMBL:CAA66916.1 xref: UniProtKB:Q99547 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005116 ! MPHOSPH6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006012 ! mphosph6-kiaa0052 physical interaction relationship: participates_in CCO:I0006013 ! mphosph6-parn physical interaction relationship: participates_in CCO:I0006014 ! mphosph6-pmscl2 physical interaction relationship: participates_in CCO:I0006485 ! mphosph6-eif3s4 physical interaction relationship: participates_in CCO:I0006486 ! mphosph6-snx9 physical interaction relationship: participates_in CCO:I0006487 ! mphosph6-thop1 physical interaction relationship: participates_in CCO:I0006488 ! mphosph6-q9y448 physical interaction relationship: participates_in CCO:I0006489 ! mphosph6-dncl2a physical interaction relationship: participates_in CCO:I0006490 ! mphosph6-rps20 physical interaction relationship: participates_in CCO:I0006491 ! mphosph6-dnm2 physical interaction relationship: participates_in CCO:I0006492 ! mphosph6-ded physical interaction relationship: participates_in CCO:I0006493 ! mphosph6-dkfzp762i16 physical interaction relationship: participates_in CCO:I0008022 ! mphosph6-tle1 physical interaction relationship: participates_in CCO:I0008023 ! mphosph6-tp53 physical interaction relationship: participates_in CCO:I0008134 ! mphosph6-rif1 physical interaction relationship: participates_in CCO:I0008135 ! mphosph6-unc119 physical interaction relationship: participates_in CCO:I0008136 ! mphosph6-zhx1 physical interaction relationship: participates_in CCO:I0008272 ! mphosph6-aplp1 physical interaction relationship: participates_in CCO:I0008273 ! mphosph6-dkfzp564o05 physical interaction relationship: participates_in CCO:I0008274 ! mphosph6-gdf9 physical interaction relationship: participates_in CCO:I0008409 ! mphosph6-c14orf1 physical interaction relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: transforms_into CCO:B0012982 ! MPH6_HUMAN-Phosphothreonine147 [Term] id: CCO:B0002072 name: MPP8_HUMAN def: "M-phase phosphoprotein 8" [UniProtKB:Q99549] synonym: "Twa3" EXACT [UniProtKB:Q99549] synonym: "Two hybrid-associated protein 3 with RanBPM" EXACT [UniProtKB:Q99549] xref: EMBL:AAH03542.2 xref: EMBL:AAH46214.1 xref: EMBL:BAB71284.1 xref: EMBL:CAA66912.1 xref: EMBL:CAI16671.1 xref: EMBL:CAI41002.1 xref: EMBL:CAI46172.1 xref: EMBL:EAX08230.1 xref: UniProtKB:Q5JPE5 xref: UniProtKB:Q5JTQ0 xref: UniProtKB:Q86TK3 xref: UniProtKB:Q96MK4 xref: UniProtKB:Q99549 xref: UniProtKB:Q9BTP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005121 ! MPHOSPH8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0012991 ! MPP8_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0012992 ! MPP8_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0012993 ! MPP8_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0012994 ! MPP8_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0012995 ! MPP8_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0012996 ! MPP8_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0012997 ! MPP8_HUMAN-Phosphothreonine334 relationship: transforms_into CCO:B0012998 ! MPP8_HUMAN-Phosphothreonine385 relationship: transforms_into CCO:B0012999 ! MPP8_HUMAN-Phosphoserine392 relationship: transforms_into CCO:B0013000 ! MPP8_HUMAN-Phosphothreonine454 relationship: transforms_into CCO:B0068261 ! MPP8_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0068262 ! MPP8_HUMAN-Phosphoserine189 [Term] id: CCO:B0002074 name: MNT_HUMAN def: "Max-binding protein MNT" [UniProtKB:Q99583] synonym: "Myc antagonist MNT" EXACT [UniProtKB:Q99583] synonym: "Protein ROX" EXACT [UniProtKB:Q99583] xref: EMBL:AAI17564.1 xref: EMBL:CAA65265.1 xref: EMBL:CAA73851.1 xref: UniProtKB:Q1ED38 xref: UniProtKB:Q99583 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005107 ! MNT_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0002075 name: NECD_HUMAN def: "Necdin" [UniProtKB:Q99608] xref: EMBL:AAB39469.1 xref: EMBL:AAH08750.1 xref: EMBL:BAA22660.1 xref: UniProtKB:Q99608 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005172 ! NDN_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005782 ! gamma-tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0001733 ! perikaryon relationship: participates_in CCO:I0008359 ! arse-ndn physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002757 ! nerve growth factor receptor signaling pathway [Term] id: CCO:B0002076 name: CDCA3_HUMAN def: "Cell division cycle-associated protein 3" [UniProtKB:Q99618] synonym: "Gene-rich cluster protein C8" EXACT [UniProtKB:Q99618] synonym: "TOME-1" EXACT [UniProtKB:Q99618] synonym: "Trigger of mitotic entry protein 1" EXACT [UniProtKB:Q99618] xref: EMBL:AAB51327.1 xref: EMBL:AAH02551.1 xref: EMBL:AAH36512.1 xref: UniProtKB:Q99618 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004296 ! CDCA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005721 ! cdca3-traf2 physical interaction relationship: participates_in CCO:I0005917 ! cdca3-ctdsp1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011092 ! CDCA3_HUMAN-Phosphoserine68 relationship: transforms_into CCO:B0011093 ! CDCA3_HUMAN-Phosphothreonine159 relationship: transforms_into CCO:B0011094 ! CDCA3_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0011095 ! CDCA3_HUMAN-Phosphothreonine177 relationship: transforms_into CCO:B0011096 ! CDCA3_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0011097 ! CDCA3_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0048189 ! CDCA3_HUMAN-Phosphothreonine70 relationship: transforms_into CCO:B0048190 ! CDCA3_HUMAN-Phosphothreonine202 relationship: transforms_into CCO:B0064212 ! CDCA3_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0064213 ! CDCA3_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0064214 ! CDCA3_HUMAN-Phosphothreonine37 relationship: transforms_into CCO:B0064215 ! CDCA3_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0064216 ! CDCA3_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0064217 ! CDCA3_HUMAN-Phosphothreonine76 relationship: transforms_into CCO:B0064218 ! CDCA3_HUMAN-Phosphoserine87 [Term] id: CCO:B0002077 name: RAD9A_HUMAN def: "Cell cycle checkpoint control protein RAD9A" [UniProtKB:Q99638] synonym: "DNA repair exonuclease rad9 homolog A" EXACT [UniProtKB:Q99638] synonym: "EC 3.1.11.2" EXACT [UniProtKB:Q99638] synonym: "hRAD9" EXACT [UniProtKB:Q99638] xref: EMBL:AAB39928.1 xref: EMBL:AAH14848.1 xref: EMBL:AAU89725.1 xref: EMBL:CAG38746.1 xref: UniProtKB:Q6FI29 xref: UniProtKB:Q96C41 xref: UniProtKB:Q99638 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005419 ! RAD9A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000007 ! DNA replication checkpoint relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0013671 ! RAD9A_HUMAN-Phosphotyrosine28 relationship: transforms_into CCO:B0013672 ! RAD9A_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0013673 ! RAD9A_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0013674 ! RAD9A_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0013675 ! RAD9A_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0013676 ! RAD9A_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0013677 ! RAD9A_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0013678 ! RAD9A_HUMAN-Phosphoserine387 [Term] id: CCO:B0002078 name: PMYT1_HUMAN def: "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase" [UniProtKB:Q99640] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q99640] synonym: "Myt1 kinase" EXACT [UniProtKB:Q99640] xref: EMBL:AAB71843.1 xref: EMBL:AAC04477.1 xref: EMBL:AAC04478.1 xref: EMBL:AAC50949.1 xref: EMBL:AAN40703.1 xref: EMBL:CAD28540.1 xref: UniProtKB:O14731 xref: UniProtKB:Q7LE24 xref: UniProtKB:Q8TCM9 xref: UniProtKB:Q99640 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005347 ! PKMYT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006959 ! pkmyt1-cdc2-1 phosphorylation relationship: participates_in CCO:I0007087 ! pkmyt1-cdc2-2 phosphorylation relationship: participates_in CCO:I0007244 ! pkmyt1-ccnb1-1 physical interaction relationship: participates_in CCO:I0007245 ! ccnb1-pkmyt1-1 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000099 ! regulation of mitosis relationship: transforms_into CCO:B0013588 ! PMYT1_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0013589 ! PMYT1_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0013590 ! PMYT1_HUMAN-Phosphoserine426 relationship: transforms_into CCO:B0013591 ! PMYT1_HUMAN-Phosphothreonine495 [Term] id: CCO:B0002079 name: Q99648_HUMAN def: "Septin" [UniProtKB:Q99648] xref: EMBL:AAC39780.1 xref: UniProtKB:Q99648 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005588 ! SEPT5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002080 name: KIF2C_HUMAN def: "Kinesin-like protein KIF2C" [UniProtKB:Q99661] synonym: "Kinesin-like protein 6" EXACT [UniProtKB:Q99661] synonym: "MCAK" EXACT [UniProtKB:Q99661] synonym: "Mitotic centromere-associated kinesin" EXACT [UniProtKB:Q99661] xref: EMBL:AAC27660.1 xref: EMBL:AAH08764.1 xref: EMBL:AAH14924.1 xref: EMBL:AAK20168.1 xref: UniProtKB:Q96C18 xref: UniProtKB:Q96HB8 xref: UniProtKB:Q99661 xref: UniProtKB:Q9BWV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004947 ! KIF2C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0012603 ! KIF2C_HUMAN-Phosphoserine628 relationship: transforms_into CCO:B0012604 ! KIF2C_HUMAN-Phosphoserine629 relationship: transforms_into CCO:B0012605 ! KIF2C_HUMAN-Phosphoserine632 relationship: transforms_into CCO:B0012606 ! KIF2C_HUMAN-Phosphoserine633 relationship: transforms_into CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0067363 ! KIF2C_HUMAN-Phosphoserine166 [Term] id: CCO:B0002081 name: CGRE1_HUMAN def: "Cell growth regulator with EF hand domain protein 1" [UniProtKB:Q99674] synonym: "Cell growth regulatory gene 11 protein" EXACT [UniProtKB:Q99674] xref: EMBL:AAC50896.1 xref: EMBL:AAH34764.1 xref: EMBL:AAX93168.1 xref: EMBL:BAF82817.1 xref: EMBL:EAX00637.1 xref: UniProtKB:A6NHV7 xref: UniProtKB:Q8N4B7 xref: UniProtKB:Q99674 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004339 ! CGREF1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0002082 name: CGRF1_HUMAN def: "Cell growth regulator with RING finger domain protein 1" [UniProtKB:Q99675] synonym: "Cell growth regulatory gene 19 protein" EXACT [UniProtKB:Q99675] synonym: "RING finger protein 197" EXACT [UniProtKB:Q99675] xref: EMBL:AAC50897.1 xref: EMBL:AAH15063.1 xref: UniProtKB:Q96BX2 xref: UniProtKB:Q99675 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004340 ! CGRRF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0002083 name: GFI1_HUMAN def: "Zinc finger protein Gfi-1" [UniProtKB:Q99684] synonym: "Growth factor independent protein 1" EXACT [UniProtKB:Q99684] synonym: "Zinc finger protein 163" EXACT [UniProtKB:Q99684] xref: EMBL:AAB37272.1 xref: EMBL:AAH32751.1 xref: EMBL:AAH74866.1 xref: EMBL:AAH74867.1 xref: UniProtKB:Q8N564 xref: UniProtKB:Q99684 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004695 ! GFI1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007629 ! gfi1-prkcabp physical interaction relationship: participates_in CCO:P0000013 ! G1/S-specific transcription in mitotic cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000888 ! negative regulation of cell fate specification relationship: participates_in CCO:P0002106 ! positive regulation of cell fate specification [Term] id: CCO:B0002084 name: RBBP8_HUMAN def: "Retinoblastoma-binding protein 8" [UniProtKB:Q99708] synonym: "CtBP-interacting protein" EXACT [UniProtKB:Q99708] synonym: "CtIP" EXACT [UniProtKB:Q99708] synonym: "RBBP-8" EXACT [UniProtKB:Q99708] synonym: "Retinoblastoma-interacting protein and myosin-like" EXACT [UniProtKB:Q99708] synonym: "RIM" EXACT [UniProtKB:Q99708] xref: EMBL:AAC14371.1 xref: EMBL:AAC34368.1 xref: UniProtKB:O75371 xref: UniProtKB:Q99708 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005442 ! RBBP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0013747 ! RBBP8_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0013748 ! RBBP8_HUMAN-Phosphoserine664 relationship: transforms_into CCO:B0013749 ! RBBP8_HUMAN-Phosphoserine679 relationship: transforms_into CCO:B0013750 ! RBBP8_HUMAN-Phosphoserine745 [Term] id: CCO:B0002085 name: SEPT5_HUMAN def: "Septin-5" [UniProtKB:Q99719] synonym: "CDCrel-1" EXACT [UniProtKB:Q99719] synonym: "Cell division control-related protein 1" EXACT [UniProtKB:Q99719] synonym: "Peanut-like protein 1" EXACT [UniProtKB:Q99719] xref: EMBL:AAB93438.1 xref: EMBL:AAC39779.1 xref: EMBL:AAH25261.1 xref: EMBL:CAA72332.1 xref: EMBL:CAG30431.1 xref: UniProtKB:O15251 xref: UniProtKB:Q99719 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005588 ! SEPT5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:I0006498 ! lsm8-sept5 physical interaction relationship: participates_in CCO:I0006897 ! sept5-sept11 physical interaction relationship: participates_in CCO:I0006898 ! sept5-sept8 physical interaction relationship: participates_in CCO:I0006899 ! sept11-sept5 physical interaction relationship: participates_in CCO:I0007372 ! sept5-sept11-1 physical interaction relationship: participates_in CCO:I0007373 ! sept5-sept8-1 physical interaction relationship: participates_in CCO:I0007376 ! sept11-sept5-1 physical interaction relationship: participates_in CCO:I0007794 ! sept5-sept11-2 direct interaction relationship: participates_in CCO:I0008151 ! sept5-pfn2 physical interaction relationship: participates_in CCO:I0008294 ! sept5-myst2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013996 ! SEPT5_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0013997 ! SEPT5_HUMAN-Phosphothreonine336 relationship: transforms_into CCO:B0041194 ! SEPT5_HUMAN-Phosphoserine225 [Term] id: CCO:B0002086 name: BARD1_HUMAN def: "BRCA1-associated RING domain protein 1" [UniProtKB:Q99728] synonym: "BARD-1" EXACT [UniProtKB:Q99728] xref: EMBL:AAB38316.1 xref: EMBL:AAB99978.1 xref: EMBL:AAI26427.1 xref: EMBL:AAX93130.1 xref: UniProtKB:O43574 xref: UniProtKB:Q53SS5 xref: UniProtKB:Q99728 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004138 ! BARD1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001247 ! BRCA1-BARD1 complex relationship: participates_in CCO:I0006166 ! bard1-htatip physical interaction relationship: participates_in CCO:I0006167 ! bard1-zhx1 physical interaction relationship: participates_in CCO:I0006168 ! bard1-tcerg1-1 physical interaction relationship: participates_in CCO:I0006169 ! bard1-git1-1 physical interaction relationship: participates_in CCO:I0006170 ! bard1-ikbkap physical interaction relationship: participates_in CCO:I0006171 ! bard1-hbo1-1 physical interaction relationship: participates_in CCO:I0006172 ! bard1-bp465 physical interaction relationship: participates_in CCO:I0006173 ! bard1-kbtbd7 physical interaction relationship: participates_in CCO:I0006174 ! bard1-pias4 physical interaction relationship: participates_in CCO:I0006175 ! bard1-kiaa1377-1 physical interaction relationship: participates_in CCO:I0006176 ! bard1-setdb1 physical interaction relationship: participates_in CCO:I0006177 ! bard1-ptn physical interaction relationship: participates_in CCO:I0006178 ! bard1-gprasp2 physical interaction relationship: participates_in CCO:I0006179 ! bard1-fez1 physical interaction relationship: participates_in CCO:I0007078 ! bard1-git1 physical interaction relationship: participates_in CCO:I0007079 ! bard1-hbo1 physical interaction relationship: participates_in CCO:I0007080 ! bard1-kiaa1377 physical interaction relationship: participates_in CCO:I0007082 ! bard1-tcerg1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0001440 ! negative regulation of mRNA 3'-end processing relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0063730 ! BARD1_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0063731 ! BARD1_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0063732 ! BARD1_HUMAN-Phosphothreonine394 [Term] id: CCO:B0002087 name: CDC6_HUMAN def: "Cell division control protein 6 homolog" [UniProtKB:Q99741] synonym: "CDC6-related protein" EXACT [UniProtKB:Q99741] synonym: "HsCDC18" EXACT [UniProtKB:Q99741] synonym: "HsCDC6" EXACT [UniProtKB:Q99741] synonym: "p62(cdc6)" EXACT [UniProtKB:Q99741] xref: EMBL:AAB38317.1 xref: EMBL:AAC52071.1 xref: EMBL:AAH25232.1 xref: EMBL:AAN10296.1 xref: UniProtKB:Q8TB30 xref: UniProtKB:Q99741 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004292 ! CDC6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006075 ! orc1l-hscdc6 direct interaction relationship: participates_in CCO:I0006100 ! orc2l-hscdc6 direct interaction relationship: participates_in CCO:I0006104 ! mcm10-hscdc6 direct interaction relationship: participates_in CCO:I0006111 ! mcm2-hscdc6 direct interaction relationship: participates_in CCO:I0006122 ! hscdc6-orc5l direct interaction relationship: participates_in CCO:I0006123 ! orc3l-hscdc6 direct interaction relationship: participates_in CCO:I0006124 ! hscdc6-orc6l direct interaction relationship: participates_in CCO:I0006128 ! cdkn2a-hscdc6 direct interaction relationship: participates_in CCO:I0006136 ! cdkn1a-hscdc6 direct interaction relationship: participates_in CCO:I0006154 ! mcm3-hscdc6 direct interaction relationship: participates_in CCO:I0006613 ! cdc6-ubiq-1 physical interaction relationship: participates_in CCO:I0007239 ! cdt1-cdc6-1 physical interaction relationship: participates_in CCO:I0007240 ! cdt1-cdc6-2 physical interaction relationship: participates_in CCO:P0000007 ! DNA replication checkpoint relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000100 ! traversing start control point of mitotic cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011087 ! CDC6_HUMAN-Phosphothreonine166 relationship: transforms_into CCO:B0064198 ! CDC6_HUMAN-Phosphoserine45 [Term] id: CCO:B0002088 name: Q99773_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q99773] xref: EMBL:AAB50210.1 xref: UniProtKB:Q99773 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: participates_in CCO:P0000300 ! centrosome duplication [Term] id: CCO:B0002089 name: TCPH_HUMAN def: "T-complex protein 1 subunit eta" [UniProtKB:Q99832] synonym: "CCT-eta" EXACT [UniProtKB:Q99832] synonym: "HIV-1 Nef-interacting protein" EXACT [UniProtKB:Q99832] synonym: "TCP-1-eta" EXACT [UniProtKB:Q99832] xref: EMBL:AAB41437.1 xref: EMBL:AAC96011.1 xref: EMBL:AAH19296.1 xref: EMBL:AAH88351.1 xref: EMBL:AAX88902.1 xref: EMBL:CAG38749.1 xref: UniProtKB:O14871 xref: UniProtKB:Q6FI26 xref: UniProtKB:Q99832 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005754 ! CCT7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000400 ! chaperonin-containing T-complex relationship: participates_in CCO:I0006377 ! map3k3-cct7 physical interaction relationship: participates_in CCO:I0006409 ! tbk1-cct7 physical interaction relationship: participates_in CCO:I0008077 ! cct7-med31 physical interaction relationship: participates_in CCO:I0008078 ! cct7-htatip physical interaction relationship: transforms_into CCO:B0014325 ! TCPH_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0002090 name: SPI2A_HUMAN def: "Spindlin-2A" [UniProtKB:Q99865] synonym: "Protein DXF34" EXACT [UniProtKB:Q99865] synonym: "SPIN-2" EXACT [UniProtKB:Q99865] synonym: "SPIN-2A" EXACT [UniProtKB:Q99865] synonym: "Spindlin-like protein 2A" EXACT [UniProtKB:Q99865] xref: EMBL:AAH71694.1 xref: EMBL:CAA70988.1 xref: EMBL:CAI42597.1 xref: UniProtKB:O75650 xref: UniProtKB:Q6IPW2 xref: UniProtKB:Q99865 xref: UniProtKB:Q9UJJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005661 ! SPIN2A_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002091 name: CITE2_HUMAN def: "Cbp/p300-interacting transactivator 2" [UniProtKB:Q99967] synonym: "MRG-1" EXACT [UniProtKB:Q99967] synonym: "MSG-related protein 1" EXACT [UniProtKB:Q99967] synonym: "P35srj" EXACT [UniProtKB:Q99967] xref: EMBL:AAC51114.1 xref: EMBL:AAD10055.1 xref: EMBL:AAF01263.1 xref: EMBL:AAF01264.1 xref: EMBL:AAH04377.1 xref: EMBL:CAH70354.1 xref: UniProtKB:O95426 xref: UniProtKB:Q5VTF4 xref: UniProtKB:Q99967 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004354 ! CITED2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006724 ! p300-tfap2a-2 physical interaction relationship: participates_in CCO:I0006891 ! cited2-tfap2a-1 physical interaction relationship: participates_in CCO:I0006892 ! cited2-tfap2b-1 physical interaction relationship: participates_in CCO:I0006893 ! cited2-tfap2c-1 physical interaction relationship: participates_in CCO:I0007147 ! p300-cited2-1 physical interaction relationship: participates_in CCO:I0007417 ! p300-tfap2a-6 physical interaction relationship: participates_in CCO:I0007793 ! tfap2c-cited2-1 physical interaction relationship: participates_in CCO:P0000247 ! positive regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001272 ! positive regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0002092 name: CND3_HUMAN def: "Condensin complex subunit 3" [UniProtKB:Q9BPX3] synonym: "Antigen NY-MEL-3" EXACT [UniProtKB:Q9BPX3] synonym: "Chromosome-associated protein G" EXACT [UniProtKB:Q9BPX3] synonym: "Condensin subunit CAP-G" EXACT [UniProtKB:Q9BPX3] synonym: "hCAP-G" EXACT [UniProtKB:Q9BPX3] synonym: "Non-SMC condensin I complex subunit G" EXACT [UniProtKB:Q9BPX3] synonym: "XCAP-G homolog" EXACT [UniProtKB:Q9BPX3] xref: EMBL:AAG30732.1 xref: EMBL:AAG49627.1 xref: EMBL:AAH00827.1 xref: EMBL:AAH02337.2 xref: EMBL:AAI01477.1 xref: EMBL:BAB14069.1 xref: EMBL:BAB14429.1 xref: EMBL:BAB21557.1 xref: EMBL:BAB55165.1 xref: UniProtKB:Q3MJE0 xref: UniProtKB:Q96SV9 xref: UniProtKB:Q9BPX3 xref: UniProtKB:Q9BUR3 xref: UniProtKB:Q9BVY1 xref: UniProtKB:Q9H914 xref: UniProtKB:Q9H9Z6 xref: UniProtKB:Q9HBI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004378 ! NCAPG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011304 ! CND3_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0011305 ! CND3_HUMAN-Phosphothreonine463 relationship: transforms_into CCO:B0011306 ! CND3_HUMAN-Phosphoserine467 relationship: transforms_into CCO:B0011307 ! CND3_HUMAN-Phosphoserine674 relationship: transforms_into CCO:B0011308 ! CND3_HUMAN-Phosphoserine944 relationship: transforms_into CCO:B0011309 ! CND3_HUMAN-Phosphoserine959 relationship: transforms_into CCO:B0011310 ! CND3_HUMAN-Phosphoserine973 relationship: transforms_into CCO:B0011311 ! CND3_HUMAN-Phosphoserine975 relationship: transforms_into CCO:B0011312 ! CND3_HUMAN-Phosphoserine1015 relationship: transforms_into CCO:B0041129 ! CND3_HUMAN-Phosphothreonine686 relationship: transforms_into CCO:B0064413 ! CND3_HUMAN-Phosphoserine1002 [Term] id: CCO:B0002093 name: SPI2B_HUMAN def: "Spindlin-2B" [UniProtKB:Q9BPZ2] synonym: "SPIN-2" EXACT [UniProtKB:Q9BPZ2] synonym: "SPIN-2B" EXACT [UniProtKB:Q9BPZ2] synonym: "Spindlin-like protein 2B" EXACT [UniProtKB:Q9BPZ2] xref: EMBL:AAH00044.1 xref: EMBL:AAH71974.1 xref: EMBL:AAK37566.1 xref: EMBL:CAI42600.1 xref: UniProtKB:Q7Z2M0 xref: UniProtKB:Q9BPZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005662 ! SPIN2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002094 name: LZTS2_HUMAN def: "Leucine zipper putative tumor suppressor 2" [UniProtKB:Q9BRK4] synonym: "Protein LAPSER1" EXACT [UniProtKB:Q9BRK4] xref: EMBL:AAH06212.2 xref: EMBL:AAH58938.1 xref: EMBL:AAK31577.1 xref: EMBL:BAB47442.1 xref: EMBL:CAD39005.1 xref: UniProtKB:Q8N3I0 xref: UniProtKB:Q96J79 xref: UniProtKB:Q96JL2 xref: UniProtKB:Q9BRK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005001 ! LZTS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005730 ! lzts2-rbpms physical interaction relationship: participates_in CCO:I0005750 ! lzts2-pak7 physical interaction relationship: participates_in CCO:I0005774 ! lzts2-znf581 physical interaction relationship: participates_in CCO:I0005816 ! lzts2-trim29 physical interaction relationship: participates_in CCO:I0005864 ! lzts2-pepp2 physical interaction relationship: participates_in CCO:I0005878 ! lzts2-traf2 physical interaction relationship: participates_in CCO:I0006644 ! lzts2-a2bp1 physical interaction relationship: participates_in CCO:I0007658 ! gfi1b-lzts2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0002095 name: APC13_HUMAN def: "Anaphase-promoting complex subunit 13" [UniProtKB:Q9BS18] synonym: "APC13" EXACT [UniProtKB:Q9BS18] synonym: "Cylosome subunit 13" EXACT [UniProtKB:Q9BS18] xref: EMBL:AAH05398.1 xref: EMBL:CAB43251.1 xref: UniProtKB:Q9BS18 xref: UniProtKB:Q9Y3V0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004053 ! ANAPC13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002096 name: Q9BSP9_HUMAN def: "DST protein" [UniProtKB:Q9BSP9] xref: EMBL:AAH04912.2 xref: UniProtKB:Q9BSP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004183 ! DST_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0002097 name: CABL2_HUMAN def: "CDK5 and ABL1 enzyme substrate 2" [UniProtKB:Q9BTV7] synonym: "Ik3-2" EXACT [UniProtKB:Q9BTV7] synonym: "Interactor with CDK3 2" EXACT [UniProtKB:Q9BTV7] xref: EMBL:AAH03122.1 xref: EMBL:CAI23283.2 xref: UniProtKB:Q5JWL0 xref: UniProtKB:Q9BTV7 xref: UniProtKB:Q9BYK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004204 ! CABLES2_human relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000346 ! regulation of cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: participates_in CCO:P0003078 ! regulation of cell division [Term] id: CCO:B0002098 name: HTAI2_HUMAN def: "Oxidoreductase HTATIP2" [UniProtKB:Q9BUP3] synonym: "30 kDa HIV-1 TAT-interacting protein" EXACT [UniProtKB:Q9BUP3] synonym: "EC 1.1.1.-" EXACT [UniProtKB:Q9BUP3] synonym: "HIV-1 TAT-interactive protein 2" EXACT [UniProtKB:Q9BUP3] xref: EMBL:AAB84360.1 xref: EMBL:AAC39694.1 xref: EMBL:AAC78331.1 xref: EMBL:AAH02439.1 xref: EMBL:AAH15358.1 xref: EMBL:BAD96689.1 xref: EMBL:BAD96730.1 xref: EMBL:CAG33102.1 xref: UniProtKB:O15383 xref: UniProtKB:O60520 xref: UniProtKB:O95345 xref: UniProtKB:Q53GC1 xref: UniProtKB:Q53GG2 xref: UniProtKB:Q6IBI3 xref: UniProtKB:Q9BUP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004842 ! HTATIP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0012286 ! HTAI2_HUMAN-Phosphoserine45 [Term] id: CCO:B0002099 name: CP250_HUMAN def: "Centrosome-associated protein CEP250" [UniProtKB:Q9BV73] synonym: "C-Nap1" EXACT [UniProtKB:Q9BV73] synonym: "Centrosomal Nek2-associated protein 1" EXACT [UniProtKB:Q9BV73] synonym: "Centrosomal protein 2" EXACT [UniProtKB:Q9BV73] xref: EMBL:AAC06349.1 xref: EMBL:AAC07988.1 xref: EMBL:AAH01433.1 xref: EMBL:CAB89415.1 xref: UniProtKB:O14812 xref: UniProtKB:O60588 xref: UniProtKB:Q9BV73 xref: UniProtKB:Q9H450 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004389 ! CEP250_human relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000038 ! mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000167 ! regulation of centriole-centriole cohesion [Term] id: CCO:B0002100 name: KTNB1_HUMAN def: "Katanin p80 WD40-containing subunit B1" [UniProtKB:Q9BVA0] synonym: "Katanin p80 subunit B1" EXACT [UniProtKB:Q9BVA0] synonym: "p80 katanin" EXACT [UniProtKB:Q9BVA0] xref: EMBL:AAC09328.1 xref: EMBL:AAH01353.1 xref: EMBL:AAP35668.1 xref: EMBL:CAG33043.1 xref: EMBL:EAW82951.1 xref: UniProtKB:A6NCG6 xref: UniProtKB:O60620 xref: UniProtKB:Q9BVA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004964 ! KATNB1_human relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001999 ! microtubule-severing ATPase activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000546 ! katanin complex relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0001387 ! positive regulation of microtubule depolymerization relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012647 ! KTNB1_HUMAN-Phosphothreonine395 [Term] id: CCO:B0002101 name: TBB2B_HUMAN def: "Tubulin beta-2B chain" [UniProtKB:Q9BVA1] xref: EMBL:AAH01352.1 xref: EMBL:AAH63610.1 xref: EMBL:AAV38733.1 xref: EMBL:CAG33069.1 xref: EMBL:CAI40952.1 xref: UniProtKB:Q9BVA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005734 ! TUBB2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006357 ! ikbkb-q9bva1 physical interaction relationship: participates_in CCO:I0006368 ! map3k1-q9bva1 physical interaction relationship: participates_in CCO:I0006380 ! map3k3-q9bva1 physical interaction relationship: participates_in CCO:I0006390 ! map3k14-q9bva1 physical interaction relationship: participates_in CCO:I0006395 ! ripk2-q9bva1 physical interaction relationship: participates_in CCO:I0006406 ! map3k7ip1-q9bva1 physical interaction relationship: participates_in CCO:I0006414 ! tnfrsf1a-q9bva1 physical interaction relationship: participates_in CCO:I0006416 ! tnfrsf1b-q9bva1 physical interaction relationship: participates_in CCO:I0006421 ! traf6-q9bva1 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0031378 ! TBB2B_HUMAN-Phosphotyrosine36 [Term] id: CCO:B0002103 name: GNL3_HUMAN def: "Guanine nucleotide-binding protein-like 3" [UniProtKB:Q9BVP2] synonym: "E2-induced gene 3 protein" EXACT [UniProtKB:Q9BVP2] synonym: "NNP47" EXACT [UniProtKB:Q9BVP2] synonym: "Novel nucleolar protein 47" EXACT [UniProtKB:Q9BVP2] synonym: "Nucleolar GTP-binding protein 3" EXACT [UniProtKB:Q9BVP2] synonym: "Nucleostemin" EXACT [UniProtKB:Q9BVP2] xref: EMBL:AAF09482.1 xref: EMBL:AAH01024.1 xref: EMBL:BAB55168.1 xref: EMBL:BAB55169.1 xref: UniProtKB:Q96SV6 xref: UniProtKB:Q96SV7 xref: UniProtKB:Q9BVP2 xref: UniProtKB:Q9UJY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004712 ! GNL3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0006980 ! gnl3-p53 physical interaction relationship: participates_in CCO:I0007430 ! gnl3-ppp2r5a-1 physical interaction relationship: participates_in CCO:I0007431 ! ppp2r5a-gnl3 physical interaction relationship: participates_in CCO:I0007962 ! gnl3-ppp2r5a physical interaction relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0002104 name: TIPIN_HUMAN def: "TIMELESS-interacting protein" [UniProtKB:Q9BVW5] xref: EMBL:AAH00870.1 xref: EMBL:BAA91229.1 xref: EMBL:DAA01365.1 xref: EMBL:EAW77762.1 xref: UniProtKB:Q9BVW5 xref: UniProtKB:Q9NWZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005785 ! TIPIN_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000117 ! nuclear chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000007 ! DNA replication checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000186 ! intra-S DNA damage checkpoint relationship: participates_in CCO:P0000215 ! regulation of S phase relationship: participates_in CCO:P0000216 ! regulation of DNA replication during S phase relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002848 ! replication fork protection relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014380 ! TIPIN_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0071408 ! TIPIN_HUMAN-Phosphoserine194 [Term] id: CCO:B0002105 name: KIFC1_HUMAN def: "Kinesin-like protein KIFC1" [UniProtKB:Q9BW19] synonym: "Kinesin-like protein 2" EXACT [UniProtKB:Q9BW19] synonym: "Kinesin-related protein HSET" EXACT [UniProtKB:Q9BW19] xref: EMBL:AAH00712.2 xref: EMBL:AAH63567.1 xref: EMBL:AAH73878.1 xref: EMBL:AAH98438.1 xref: EMBL:AAI21042.1 xref: EMBL:AAI21043.1 xref: EMBL:BAA03509.1 xref: EMBL:CAA09217.1 xref: EMBL:CAA16157.1 xref: EMBL:CAB63782.1 xref: EMBL:CAI18269.1 xref: EMBL:CAI41792.1 xref: EMBL:CAM26294.1 xref: UniProtKB:O60887 xref: UniProtKB:Q14834 xref: UniProtKB:Q4KMP0 xref: UniProtKB:Q5SU09 xref: UniProtKB:Q6GMS7 xref: UniProtKB:Q6P4A5 xref: UniProtKB:Q9BW19 xref: UniProtKB:Q9UQP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004951 ! KIFC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012609 ! KIFC1_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 [Term] id: CCO:B0002106 name: SYCP2_HUMAN def: "Synaptonemal complex protein 2" [UniProtKB:Q9BX26] synonym: "hsSCP2" EXACT [UniProtKB:Q9BX26] synonym: "SCP-2" EXACT [UniProtKB:Q9BX26] synonym: "Synaptonemal complex lateral element protein" EXACT [UniProtKB:Q9BX26] xref: EMBL:CAA70171.1 xref: EMBL:CAB45780.1 xref: EMBL:CAC36022.2 xref: EMBL:CAI21795.1 xref: UniProtKB:O75763 xref: UniProtKB:Q5JX11 xref: UniProtKB:Q9BX26 xref: UniProtKB:Q9NTX8 xref: UniProtKB:Q9UG27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005711 ! SYCP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000122 ! synaptonemal complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000119 ! meiotic prophase I relationship: participates_in CCO:P0000121 ! synaptonemal complex assembly relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002107 name: FANCJ_HUMAN def: "Fanconi anemia group J protein" [UniProtKB:Q9BX63] synonym: "ATP-dependent RNA helicase BRIP1" EXACT [UniProtKB:Q9BX63] synonym: "BRCA1-associated C-terminal helicase 1" EXACT [UniProtKB:Q9BX63] synonym: "BRCA1-interacting protein 1" EXACT [UniProtKB:Q9BX63] synonym: "BRCA1-interacting protein C-terminal helicase 1" EXACT [UniProtKB:Q9BX63] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9BX63] synonym: "Protein FACJ" EXACT [UniProtKB:Q9BX63] xref: EMBL:AAI01473.1 xref: EMBL:AAI01475.1 xref: EMBL:AAK38111.1 xref: EMBL:BAC11156.1 xref: UniProtKB:Q3MJE2 xref: UniProtKB:Q8NCI5 xref: UniProtKB:Q9BX63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004613 ! BRIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0011849 ! FANCJ_HUMAN-Phosphoserine990 relationship: transforms_into CCO:B0011850 ! FANCJ_HUMAN-Phosphoserine1032 relationship: transforms_into CCO:B0048260 ! FANCJ_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0048261 ! FANCJ_HUMAN-Phosphothreonine113 relationship: transforms_into CCO:B0066119 ! FANCJ_HUMAN-Phosphothreonine918 relationship: transforms_into CCO:B0066120 ! FANCJ_HUMAN-Phosphotyrosine921 relationship: transforms_into CCO:B0066121 ! FANCJ_HUMAN-Phosphoserine927 relationship: transforms_into CCO:B0066122 ! FANCJ_HUMAN-Phosphoserine930 [Term] id: CCO:B0002108 name: NUSAP_HUMAN def: "Nucleolar and spindle-associated protein 1" [UniProtKB:Q9BXS6] synonym: "NuSAP" EXACT [UniProtKB:Q9BXS6] xref: EMBL:AAF24034.1 xref: EMBL:AAF67624.1 xref: EMBL:AAG25874.1 xref: EMBL:AAH01308.1 xref: EMBL:AAH10838.2 xref: EMBL:AAH12887.2 xref: EMBL:AAH24772.1 xref: EMBL:AAK28023.1 xref: EMBL:BAB14586.1 xref: EMBL:BAD96539.1 xref: EMBL:EAW92483.1 xref: UniProtKB:Q53GW2 xref: UniProtKB:Q8TBT4 xref: UniProtKB:Q96E58 xref: UniProtKB:Q96FJ1 xref: UniProtKB:Q9BXS6 xref: UniProtKB:Q9GZM9 xref: UniProtKB:Q9NZ85 xref: UniProtKB:Q9UI70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005226 ! NUSAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000040 ! cytokinesis after mitosis relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0000225 ! establishment of mitotic spindle localization relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013327 ! NUSAP_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0013328 ! NUSAP_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0013329 ! NUSAP_HUMAN-Phosphothreonine314 relationship: transforms_into CCO:B0048342 ! NUSAP_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0048343 ! NUSAP_HUMAN-Phosphothreonine244 relationship: transforms_into CCO:B0048344 ! NUSAP_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0068947 ! NUSAP_HUMAN-Phosphothreonine182 relationship: transforms_into CCO:B0068948 ! NUSAP_HUMAN-Phosphothreonine349 relationship: transforms_into CCO:B0068949 ! NUSAP_HUMAN-Phosphoserine352 [Term] id: CCO:B0002109 name: FACD2_HUMAN def: "Fanconi anemia group D2 protein" [UniProtKB:Q9BXW9] synonym: "Protein FACD2" EXACT [UniProtKB:Q9BXW9] xref: EMBL:AAH13582.1 xref: EMBL:AAK15369.1 xref: EMBL:AAK18772.1 xref: EMBL:AAK18773.1 xref: EMBL:AAL05980.1 xref: EMBL:ABC67466.1 xref: EMBL:BAB14132.1 xref: EMBL:CAH10647.1 xref: UniProtKB:Q2LA86 xref: UniProtKB:Q69YP9 xref: UniProtKB:Q6PJN7 xref: UniProtKB:Q9BQ06 xref: UniProtKB:Q9BXW9 xref: UniProtKB:Q9H9T9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004605 ! FANCD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006281 ! fancd2-brca2-2 physical interaction relationship: participates_in CCO:I0006422 ! traf6-fancd2 physical interaction relationship: participates_in CCO:I0006440 ! tnfrsf1a-fancd2 physical interaction relationship: participates_in CCO:I0006442 ! tnfrsf1b-fancd2 physical interaction relationship: participates_in CCO:I0006509 ! fance-fancd2-2 physical interaction relationship: participates_in CCO:I0006611 ! fancd2-fance-1 physical interaction relationship: participates_in CCO:I0007073 ! fancd2-brca2-1 physical interaction relationship: participates_in CCO:I0007402 ! fance-fanca-1 physical interaction relationship: participates_in CCO:I0007404 ! fance-fancd2-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011814 ! FACD2_HUMAN-Phosphoserine167 relationship: transforms_into CCO:B0011815 ! FACD2_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0011816 ! FACD2_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0011817 ! FACD2_HUMAN-Phosphoserine592 relationship: transforms_into CCO:B0011818 ! FACD2_HUMAN-Phosphothreonine596 relationship: transforms_into CCO:B0011819 ! FACD2_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0011820 ! FACD2_HUMAN-Phosphoserine1401 relationship: transforms_into CCO:B0011821 ! FACD2_HUMAN-Phosphoserine1404 relationship: transforms_into CCO:B0011822 ! FACD2_HUMAN-Phosphoserine1412 relationship: transforms_into CCO:B0011823 ! FACD2_HUMAN-Phosphoserine1418 relationship: transforms_into CCO:B0048258 ! FACD2_HUMAN-Phosphotyrosine684 [Term] id: CCO:B0002110 name: CADM1_HUMAN def: "Cell adhesion molecule 1 precursor" [UniProtKB:Q9BY67] synonym: "Immunoglobulin superfamily member 4" EXACT [UniProtKB:Q9BY67] synonym: "NECL-2" EXACT [UniProtKB:Q9BY67] synonym: "Nectin-like protein 2" EXACT [UniProtKB:Q9BY67] synonym: "SgIGSF" EXACT [UniProtKB:Q9BY67] synonym: "Spermatogenic immunoglobulin superfamily" EXACT [UniProtKB:Q9BY67] synonym: "Synaptic cell adhesion molecule" EXACT [UniProtKB:Q9BY67] synonym: "TSLC-1" EXACT [UniProtKB:Q9BY67] synonym: "Tumor suppressor in lung cancer 1" EXACT [UniProtKB:Q9BY67] xref: EMBL:AAF69029.1 xref: EMBL:BAC11657.1 xref: EMBL:BAC66178.1 xref: UniProtKB:Q86WB8 xref: UniProtKB:Q8N2F4 xref: UniProtKB:Q9BY67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004210 ! CADM1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0002054 ! susceptibility to natural killer cell mediated cytotoxicity relationship: participates_in CCO:P0002637 ! positive regulation of natural killer cell mediated cytotoxicity [Term] id: CCO:B0002111 name: PCGF6_HUMAN def: "Polycomb group RING finger protein 6" [UniProtKB:Q9BYE7] synonym: "Mel18 and Bmi1-like RING finger" EXACT [UniProtKB:Q9BYE7] synonym: "RING finger protein 134" EXACT [UniProtKB:Q9BYE7] xref: EMBL:AAH07602.1 xref: EMBL:AAH10235.1 xref: EMBL:BAB40779.1 xref: EMBL:BAB55431.1 xref: EMBL:CAI16745.1 xref: EMBL:CAI16746.1 xref: UniProtKB:Q5SYD1 xref: UniProtKB:Q5SYD6 xref: UniProtKB:Q96ID9 xref: UniProtKB:Q96SJ1 xref: UniProtKB:Q9BYE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005277 ! PCGF6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001285 ! PcG protein complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0013432 ! PCGF6_HUMAN-Phosphoserine30 [Term] id: CCO:B0002112 name: PAR6G_HUMAN def: "Partitioning defective 6 homolog gamma" [UniProtKB:Q9BYG4] synonym: "PAR-6 gamma" EXACT [UniProtKB:Q9BYG4] synonym: "PAR6D" EXACT [UniProtKB:Q9BYG4] xref: EMBL:AAH60797.1 xref: EMBL:BAB40757.1 xref: UniProtKB:Q9BYG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005264 ! PARD6G_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0005992 ! pard6g-prkci-1 physical interaction relationship: participates_in CCO:I0005997 ! pard6g-rac1-1 physical interaction relationship: participates_in CCO:I0005998 ! pard6g-cdc42-1 physical interaction relationship: participates_in CCO:I0006834 ! cdc42-pard6g-1 physical interaction relationship: participates_in CCO:I0006837 ! rac1-pard6g-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002113 name: PAR6B_HUMAN def: "Partitioning defective 6 homolog beta" [UniProtKB:Q9BYG5] synonym: "PAR-6 beta" EXACT [UniProtKB:Q9BYG5] synonym: "PAR-6B" EXACT [UniProtKB:Q9BYG5] xref: EMBL:AAH60847.1 xref: EMBL:BAB40756.1 xref: EMBL:CAB44747.3 xref: UniProtKB:Q9BYG5 xref: UniProtKB:Q9Y510 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005263 ! PARD6B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:I0005990 ! pard6b-prkci-1 physical interaction relationship: participates_in CCO:I0005991 ! pard6b-prkcz-1 physical interaction relationship: participates_in CCO:I0005995 ! pard6b-rac1-1 physical interaction relationship: participates_in CCO:I0005996 ! pard6b-cdc42-4 physical interaction relationship: participates_in CCO:I0006830 ! prkci-pard6b-1 physical interaction relationship: participates_in CCO:I0006831 ! prkcz-pard6b-1 physical interaction relationship: participates_in CCO:I0006833 ! cdc42-pard6b-1 physical interaction relationship: participates_in CCO:I0006836 ! rac1-pard6b-1 physical interaction relationship: participates_in CCO:I0006838 ! pard6b-rac1-2 physical interaction relationship: participates_in CCO:I0006839 ! pard6b-cdc42-5 physical interaction relationship: participates_in CCO:I0007062 ! pard6b-prkci-2 physical interaction relationship: participates_in CCO:I0007063 ! rac1-pard6b-2 physical interaction relationship: participates_in CCO:I0007064 ! cdc42-pard6b-2 physical interaction relationship: participates_in CCO:I0007199 ! pard3-pard6b-2 physical interaction relationship: participates_in CCO:I0007204 ! pard6a-par6b-1 physical interaction relationship: participates_in CCO:I0007207 ! prkci-pard6b-2 physical interaction relationship: participates_in CCO:I0007215 ! pard6b-ywhah-1 physical interaction relationship: participates_in CCO:I0007216 ! pard6b-ywhaz-1 physical interaction relationship: participates_in CCO:I0007225 ! pard6b-cdc42-6 physical interaction relationship: participates_in CCO:I0007226 ! cdc42-pard6b-3 physical interaction relationship: participates_in CCO:I0007227 ! pard6b-pnma1-1 physical interaction relationship: participates_in CCO:I0007228 ! pnma1-pard6b-1 physical interaction relationship: participates_in CCO:I0007229 ! pard6b-prkci-3 physical interaction relationship: participates_in CCO:I0007230 ! pard6b-pard3-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002114 name: Q9BYG9_HUMAN def: "Nucleophosmin (Nucleolar phosphoprotein B23, numatrin)" [UniProtKB:Q9BYG9] synonym: "Nucleophosmin/B23.2" EXACT [UniProtKB:Q9BYG9] xref: EMBL:AAI07755.1 xref: EMBL:BAB40600.1 xref: UniProtKB:Q9BYG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005212 ! NPM1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:P0000108 ! centrosome cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0002115 name: NUF2_HUMAN def: "Kinetochore protein Nuf2" [UniProtKB:Q9BZD4] synonym: "Cell division cycle-associated protein 1" EXACT [UniProtKB:Q9BZD4] synonym: "hNuf2" EXACT [UniProtKB:Q9BZD4] synonym: "hNuf2R" EXACT [UniProtKB:Q9BZD4] synonym: "hsNuf2" EXACT [UniProtKB:Q9BZD4] xref: EMBL:AAH08489.1 xref: EMBL:AAH21171.2 xref: EMBL:AAK01426.1 xref: EMBL:BAB59141.1 xref: EMBL:BAB59142.1 xref: EMBL:BAC04140.1 xref: EMBL:CAI16706.1 xref: UniProtKB:Q8WU69 xref: UniProtKB:Q96HJ4 xref: UniProtKB:Q96Q78 xref: UniProtKB:Q9BZD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005224 ! NUF2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0006225 ! cdca1_cenpb_1 colocalization relationship: participates_in CCO:I0006574 ! exoc1-nuf2 physical interaction relationship: participates_in CCO:I0006764 ! kntc2-spbc24-3 physical interaction relationship: participates_in CCO:I0007156 ! kntc2-cdca1-4 physical interaction relationship: participates_in CCO:I0007169 ! kntc2-spbc24-4 physical interaction relationship: participates_in CCO:I0007301 ! kntc2-spbc24-1 physical interaction relationship: participates_in CCO:I0007303 ! kntc2-cdca1-3 physical interaction relationship: participates_in CCO:I0007318 ! cdca1-kntc2 physical interaction relationship: participates_in CCO:I0007463 ! kntc2-cdca1-2 physical interaction relationship: participates_in CCO:I0007473 ! kntc2-cdca1-1 physical interaction relationship: participates_in CCO:I0007932 ! kntc2-spbc24-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013291 ! NUF2_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0013292 ! NUF2_HUMAN-Phosphothreonine261 [Term] id: CCO:B0002116 name: NOG1_HUMAN def: "Nucleolar GTP-binding protein 1" [UniProtKB:Q9BZE4] synonym: "Chronic renal failure gene protein" EXACT [UniProtKB:Q9BZE4] synonym: "GTP-binding protein NGB" EXACT [UniProtKB:Q9BZE4] xref: EMBL:AAD09830.1 xref: EMBL:AAH38975.1 xref: EMBL:AAK13444.1 xref: EMBL:BAA91752.1 xref: UniProtKB:O95446 xref: UniProtKB:Q9BZE4 xref: UniProtKB:Q9NVJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005202 ! GTPBP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001238 ! negative regulation of cell-cell adhesion relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001431 ! negative regulation of protein ubiquitination relationship: participates_in CCO:P0002964 ! protein stabilization relationship: transforms_into CCO:B0013200 ! NOG1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013201 ! NOG1_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0013202 ! NOG1_HUMAN-Phosphoserine470 relationship: transforms_into CCO:B0013203 ! NOG1_HUMAN-Phosphoserine472 relationship: transforms_into CCO:B0068758 ! NOG1_HUMAN-Phosphoserine558 relationship: transforms_into CCO:B0068759 ! NOG1_HUMAN-Phosphoserine578 [Term] id: CCO:B0002117 name: DPH1_HUMAN def: "Diphthamide biosynthesis protein 1" [UniProtKB:Q9BZG8] synonym: "Diphthamide biosynthesis protein 2 homolog-like 1" EXACT [UniProtKB:Q9BZG8] synonym: "Diphthamide biosynthesis protein 2-like" EXACT [UniProtKB:Q9BZG8] synonym: "DPH-like 1" EXACT [UniProtKB:Q9BZG8] synonym: "DPH1 homolog" EXACT [UniProtKB:Q9BZG8] synonym: "DPH2-like 1" EXACT [UniProtKB:Q9BZG8] synonym: "HsDph1" EXACT [UniProtKB:Q9BZG8] synonym: "Ovarian cancer-associated gene 1 protein" EXACT [UniProtKB:Q9BZG8] xref: EMBL:AAB36297.1 xref: EMBL:AAD10198.1 xref: EMBL:AAH03099.1 xref: EMBL:AAH96088.1 xref: EMBL:AAK13428.1 xref: EMBL:AAV38681.1 xref: UniProtKB:Q16439 xref: UniProtKB:Q4VBA2 xref: UniProtKB:Q9BTW7 xref: UniProtKB:Q9BZG8 xref: UniProtKB:Q9UCY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004499 ! DPH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0002118 name: Q9BZU3_HUMAN def: "PNAS-18" [UniProtKB:Q9BZU3] synonym: "CDC28 protein kinase regulatory subunit 1B" EXACT [UniProtKB:Q9BZU3] synonym: "CDC28 protein kinase regulatory subunit 1B, isoform CRA_c" EXACT [UniProtKB:Q9BZU3] xref: EMBL:AAK07520.1 xref: EMBL:CAI13257.1 xref: EMBL:EAW53165.1 xref: UniProtKB:Q9BZU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004364 ! CKS1B_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002119 name: STRAB_HUMAN def: "STE20-related kinase adapter protein beta" [UniProtKB:Q9C0K7] synonym: "Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein" EXACT [UniProtKB:Q9C0K7] synonym: "CALS-21" EXACT [UniProtKB:Q9C0K7] synonym: "ILP-interacting protein" EXACT [UniProtKB:Q9C0K7] synonym: "Pseudokinase ALS2CR2" EXACT [UniProtKB:Q9C0K7] synonym: "STRAD beta" EXACT [UniProtKB:Q9C0K7] xref: EMBL:AAF71042.1 xref: EMBL:AAH08302.1 xref: EMBL:AAH90871.1 xref: EMBL:AAM19143.1 xref: EMBL:AAY14692.1 xref: EMBL:BAB32500.1 xref: EMBL:BAB55254.1 xref: UniProtKB:Q5BKY7 xref: UniProtKB:Q9C0K7 xref: UniProtKB:Q9P1L0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020075 ! STRADB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007208 ! als2cr2-stk11-1 physical interaction relationship: participates_in CCO:I0007209 ! mo25-als2cr2-1 physical interaction relationship: participates_in CCO:I0007223 ! stk11-als2cr2-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002120 name: PDGFD_HUMAN def: "Platelet-derived growth factor D precursor" [UniProtKB:Q9GZP0] synonym: "Iris-expressed growth factor" EXACT [UniProtKB:Q9GZP0] synonym: "PDGF-D" EXACT [UniProtKB:Q9GZP0] synonym: "SCDGF-B" EXACT [UniProtKB:Q9GZP0] synonym: "Spinal cord-derived growth factor B" EXACT [UniProtKB:Q9GZP0] xref: EMBL:AAG39287.1 xref: EMBL:AAH30645.1 xref: EMBL:AAK20081.1 xref: EMBL:AAK20082.1 xref: EMBL:AAK38840.1 xref: EMBL:AAK56136.1 xref: EMBL:AAQ89474.1 xref: EMBL:BAB18903.1 xref: UniProtKB:Q9BWV5 xref: UniProtKB:Q9GZP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005289 ! PDGFD_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0002121 name: Q9GZT1_HUMAN def: "Poly(RC) binding protein 4, isoform CRA_a" [UniProtKB:Q9GZT1] synonym: "RNA binding protein MCG10" EXACT [UniProtKB:Q9GZT1] xref: EMBL:AAG02184.1 xref: EMBL:AAG02186.1 xref: EMBL:EAW65165.1 xref: UniProtKB:Q9GZT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006047 ! PCBP4_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000065 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis [Term] id: CCO:B0002122 name: MIS12_HUMAN def: "Protein MIS12 homolog" [UniProtKB:Q9H081] xref: EMBL:AAH00229.1 xref: EMBL:BAB71088.1 xref: EMBL:CAB66840.1 xref: EMBL:CAG38491.1 xref: UniProtKB:Q96N24 xref: UniProtKB:Q9H081 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005088 ! MIS12_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000092 ! MIS12/MIND type complex relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002123 name: ILKAP_HUMAN def: "Integrin-linked kinase-associated serine/threonine phosphatase 2C" [UniProtKB:Q9H0C8] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9H0C8] synonym: "ILKAP" EXACT [UniProtKB:Q9H0C8] xref: EMBL:AAH06576.1 xref: EMBL:AAK07736.1 xref: EMBL:AAY24336.1 xref: EMBL:CAB66784.1 xref: EMBL:CAG38564.1 xref: UniProtKB:Q9H0C8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004885 ! ILKAP_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000541 ! protein serine/threonine phosphatase complex relationship: participates_in CCO:P0000101 ! regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0012374 ! ILKAP_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0036009 ! ILKAP_HUMAN-Phosphothreonine81 [Term] id: CCO:B0002124 name: RGAP1_HUMAN def: "Rac GTPase-activating protein 1" [UniProtKB:Q9H0H5] synonym: "Male germ cell RacGap" EXACT [UniProtKB:Q9H0H5] synonym: "MgcRacGAP" EXACT [UniProtKB:Q9H0H5] xref: EMBL:AAH24144.1 xref: EMBL:AAH32754.1 xref: EMBL:BAA90247.1 xref: EMBL:BAA91347.1 xref: EMBL:BAA96002.1 xref: EMBL:CAB66728.1 xref: EMBL:CAG38596.1 xref: UniProtKB:Q6PJ26 xref: UniProtKB:Q9H0H5 xref: UniProtKB:Q9NWN2 xref: UniProtKB:Q9P250 xref: UniProtKB:Q9P2W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005477 ! RACGAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000059 ! cytokinesis, contractile ring formation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000698 ! cytokinesis, initiation of separation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013837 ! RGAP1_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0013838 ! RGAP1_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0013839 ! RGAP1_HUMAN-Phosphoserine170 relationship: transforms_into CCO:B0013840 ! RGAP1_HUMAN-Phosphoserine185 relationship: transforms_into CCO:B0013841 ! RGAP1_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0013842 ! RGAP1_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0013843 ! RGAP1_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0013844 ! RGAP1_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0013845 ! RGAP1_HUMAN-Phosphothreonine342 relationship: transforms_into CCO:B0013846 ! RGAP1_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0013847 ! RGAP1_HUMAN-Phosphothreonine580 relationship: transforms_into CCO:B0013848 ! RGAP1_HUMAN-Phosphothreonine588 relationship: transforms_into CCO:B0013849 ! RGAP1_HUMAN-Phosphoserine590 relationship: transforms_into CCO:B0013850 ! RGAP1_HUMAN-Phosphothreonine606 relationship: transforms_into CCO:B0013851 ! RGAP1_HUMAN-Phosphoserine628 relationship: transforms_into CCO:B0069903 ! RGAP1_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0069904 ! RGAP1_HUMAN-Phosphoserine573 relationship: transforms_into CCO:B0069905 ! RGAP1_HUMAN-Phosphoserine591 relationship: transforms_into CCO:B0069906 ! RGAP1_HUMAN-Phosphoserine600 relationship: transforms_into CCO:B0069907 ! RGAP1_HUMAN-Phosphothreonine601 [Term] id: CCO:B0002125 name: APC1_HUMAN def: "Anaphase-promoting complex subunit 1" [UniProtKB:Q9H1A4] synonym: "APC1" EXACT [UniProtKB:Q9H1A4] synonym: "Cyclosome subunit 1" EXACT [UniProtKB:Q9H1A4] synonym: "Mitotic checkpoint regulator" EXACT [UniProtKB:Q9H1A4] synonym: "Testis-specific gene 24 protein" EXACT [UniProtKB:Q9H1A4] xref: EMBL:AAH05089.1 xref: EMBL:AAI04903.1 xref: EMBL:AAI04905.1 xref: EMBL:BAB14687.1 xref: EMBL:CAC19484.1 xref: UniProtKB:Q2M3H8 xref: UniProtKB:Q9BSE6 xref: UniProtKB:Q9H1A4 xref: UniProtKB:Q9H8D0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004054 ! ANAPC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041111 ! APC1_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0041112 ! APC1_HUMAN-Phosphoserine286 relationship: transforms_into CCO:B0041113 ! APC1_HUMAN-Phosphothreonine291 relationship: transforms_into CCO:B0041114 ! APC1_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0041115 ! APC1_HUMAN-Phosphoserine373 relationship: transforms_into CCO:B0041116 ! APC1_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0041117 ! APC1_HUMAN-Phosphothreonine537 relationship: transforms_into CCO:B0041118 ! APC1_HUMAN-Phosphotyrosine571 relationship: transforms_into CCO:B0041119 ! APC1_HUMAN-Phosphoserine686 relationship: transforms_into CCO:B0041120 ! APC1_HUMAN-Phosphoserine688 relationship: transforms_into CCO:B0041121 ! APC1_HUMAN-Phosphoserine731 relationship: transforms_into CCO:B0048162 ! APC1_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0048163 ! APC1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0065682 ! APC1_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0065683 ! APC1_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0065684 ! APC1_HUMAN-Phosphothreonine65 relationship: transforms_into CCO:B0065685 ! APC1_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0065686 ! APC1_HUMAN-Phosphoserine547 relationship: transforms_into CCO:B0065687 ! APC1_HUMAN-Phosphoserine563 [Term] id: CCO:B0002126 name: CDT1_HUMAN def: "DNA replication factor Cdt1" [UniProtKB:Q9H211] synonym: "Double parked homolog" EXACT [UniProtKB:Q9H211] synonym: "DUP" EXACT [UniProtKB:Q9H211] xref: EMBL:AAG45181.1 xref: EMBL:AAH00137.2 xref: EMBL:AAH08676.1 xref: EMBL:AAH08860.2 xref: EMBL:AAH09410.1 xref: EMBL:AAH14202.2 xref: EMBL:AAH49205.1 xref: EMBL:BAB61878.1 xref: UniProtKB:Q86XX9 xref: UniProtKB:Q96CJ5 xref: UniProtKB:Q96GK5 xref: UniProtKB:Q96H67 xref: UniProtKB:Q96HE6 xref: UniProtKB:Q9BWM0 xref: UniProtKB:Q9H211 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004315 ! CDT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006854 ! cdt1-gmnn-5 physical interaction relationship: participates_in CCO:I0007239 ! cdt1-cdc6-1 physical interaction relationship: participates_in CCO:I0007240 ! cdt1-cdc6-2 physical interaction relationship: participates_in CCO:I0007405 ! cdt1-gmnn-2 physical interaction relationship: participates_in CCO:I0007406 ! cdt1-gmnn-3 physical interaction relationship: participates_in CCO:I0007533 ! cdt1-cdk2-1 physical interaction relationship: participates_in CCO:I0007957 ! cdt1-gmnn-4 physical interaction relationship: participates_in CCO:P0000007 ! DNA replication checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000101 ! regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0001247 ! regulation of DNA replication initiation relationship: transforms_into CCO:B0011129 ! CDT1_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0064237 ! CDT1_HUMAN-Phosphothreonine29 relationship: transforms_into CCO:B0064238 ! CDT1_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0064239 ! CDT1_HUMAN-Phosphoserine372 relationship: transforms_into CCO:B0064240 ! CDT1_HUMAN-Phosphoserine394 [Term] id: CCO:B0002127 name: Q9H2F0_HUMAN def: "Cell division cycle 25C splice variant 3" [UniProtKB:Q9H2F0] xref: EMBL:AAG41886.1 xref: UniProtKB:Q9H2F0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005119 ! CDC25C_human relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000017 ! M phase of mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002128 name: TSYL2_HUMAN def: "Testis-specific Y-encoded-like protein 2" [UniProtKB:Q9H2G4] synonym: "Cell division autoantigen 1" EXACT [UniProtKB:Q9H2G4] synonym: "CTCL tumor antigen se20-4" EXACT [UniProtKB:Q9H2G4] synonym: "Cutaneous T-cell lymphoma-associated antigen se20-4" EXACT [UniProtKB:Q9H2G4] synonym: "Differentially-expressed nucleolar TGF-beta1 target protein" EXACT [UniProtKB:Q9H2G4] synonym: "NP79" EXACT [UniProtKB:Q9H2G4] synonym: "Nuclear protein of 79 kDa" EXACT [UniProtKB:Q9H2G4] synonym: "TSPY-like protein 2" EXACT [UniProtKB:Q9H2G4] xref: EMBL:AAG34906.1 xref: EMBL:AAG53596.1 xref: EMBL:AAH01566.1 xref: EMBL:AAH24270.1 xref: EMBL:AAK72407.1 xref: EMBL:BAA34802.1 xref: EMBL:CAD28461.1 xref: EMBL:CAI42531.1 xref: UniProtKB:O94799 xref: UniProtKB:Q96DG7 xref: UniProtKB:Q9BZW6 xref: UniProtKB:Q9H2G4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005841 ! TSPYL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: transforms_into CCO:B0014549 ! TSYL2_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0014550 ! TSYL2_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0014551 ! TSYL2_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0014552 ! TSYL2_HUMAN-Phosphothreonine340 relationship: transforms_into CCO:B0071614 ! TSYL2_HUMAN-Phosphoserine18 [Term] id: CCO:B0002129 name: RASF4_HUMAN def: "Ras association domain-containing protein 4" [UniProtKB:Q9H2L5] xref: EMBL:AAG44666.1 xref: EMBL:AAH32593.1 xref: EMBL:AAO61138.1 xref: EMBL:AAO61139.1 xref: EMBL:AAO61140.1 xref: EMBL:AAO61141.1 xref: EMBL:CAD28511.1 xref: EMBL:CAI13063.1 xref: UniProtKB:Q86WH5 xref: UniProtKB:Q86WH6 xref: UniProtKB:Q86WH7 xref: UniProtKB:Q8N5A9 xref: UniProtKB:Q8TCK6 xref: UniProtKB:Q9H2L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005431 ! RASSF4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0002130 name: HIPK2_HUMAN def: "Homeodomain-interacting protein kinase 2" [UniProtKB:Q9H2X6] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9H2X6] synonym: "hHIPk2" EXACT [UniProtKB:Q9H2X6] xref: EMBL:AAG35710.1 xref: EMBL:AAG41236.1 xref: EMBL:AAL37371.1 xref: EMBL:AAS00368.1 xref: UniProtKB:Q75MR7 xref: UniProtKB:Q8WWI4 xref: UniProtKB:Q9H2X6 xref: UniProtKB:Q9H2Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004809 ! HIPK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006679 ! myb-hipk2-1 physical interaction relationship: participates_in CCO:I0007338 ! bat1-hipk2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: participates_in CCO:P0001272 ! positive regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: transforms_into CCO:B0066804 ! HIPK2_HUMAN-Phosphotyrosine361 [Term] id: CCO:B0002131 name: PININ_HUMAN def: "Pinin" [UniProtKB:Q9H307] synonym: "140 kDa nuclear and cell adhesion-related phosphoprotein" EXACT [UniProtKB:Q9H307] synonym: "Desmosome-associated protein" EXACT [UniProtKB:Q9H307] synonym: "Domain-rich serine protein" EXACT [UniProtKB:Q9H307] synonym: "DRS protein" EXACT [UniProtKB:Q9H307] synonym: "DRSP" EXACT [UniProtKB:Q9H307] synonym: "Melanoma metastasis clone A protein" EXACT [UniProtKB:Q9H307] synonym: "Nuclear protein SDK3" EXACT [UniProtKB:Q9H307] synonym: "SR-like protein" EXACT [UniProtKB:Q9H307] xref: EMBL:AAB48304.1 xref: EMBL:AAF17209.1 xref: EMBL:AAG33941.1 xref: EMBL:AAH62602.1 xref: EMBL:BAD97332.1 xref: EMBL:CAA70874.1 xref: EMBL:CAA71377.1 xref: UniProtKB:O60899 xref: UniProtKB:Q53EM7 xref: UniProtKB:Q6P5X4 xref: UniProtKB:Q7KYL1 xref: UniProtKB:Q99738 xref: UniProtKB:Q9H307 xref: UniProtKB:Q9UHZ9 xref: UniProtKB:Q9UQR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005317 ! PNN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008320 ! pnn-pdpk1 physical interaction relationship: participates_in CCO:I0008504 ! pnn-vamp8 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013515 ! PININ_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013516 ! PININ_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0013518 ! PININ_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0013519 ! PININ_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0013520 ! PININ_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0013521 ! PININ_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0013522 ! PININ_HUMAN-Phosphoserine441 relationship: transforms_into CCO:B0013523 ! PININ_HUMAN-Phosphoserine443 relationship: transforms_into CCO:B0013524 ! PININ_HUMAN-Phosphoserine649 relationship: transforms_into CCO:B0013525 ! PININ_HUMAN-Phosphoserine658 relationship: transforms_into CCO:B0013526 ! PININ_HUMAN-Phosphoserine663 relationship: transforms_into CCO:B0013527 ! PININ_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0013528 ! PININ_HUMAN-Phosphoserine667 relationship: transforms_into CCO:B0013529 ! PININ_HUMAN-Phosphoserine671 relationship: transforms_into CCO:B0013530 ! PININ_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0013531 ! PININ_HUMAN-Phosphoserine690 relationship: transforms_into CCO:B0013532 ! PININ_HUMAN-Phosphoserine692 relationship: transforms_into CCO:B0013533 ! PININ_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0069310 ! PININ_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0069311 ! PININ_HUMAN-Phosphoserine552 [Term] id: CCO:B0002132 name: Q9H315_HUMAN def: "Septin" [UniProtKB:Q9H315] xref: EMBL:AAG45673.1 xref: EMBL:EAW94442.1 xref: UniProtKB:Q9H315 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006048 ! PNUTL2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0002133 name: TXNIP_HUMAN def: "Thioredoxin-interacting protein" [UniProtKB:Q9H3M7] synonym: "Thioredoxin-binding protein 2" EXACT [UniProtKB:Q9H3M7] synonym: "Vitamin D3 up-regulated protein 1" EXACT [UniProtKB:Q9H3M7] xref: EMBL:AAB31977.2 xref: EMBL:AAH93702.1 xref: EMBL:AAH93704.1 xref: EMBL:AAK37514.1 xref: EMBL:AAT01927.2 xref: EMBL:BAB18859.1 xref: EMBL:CAI22351.1 xref: UniProtKB:Q16226 xref: UniProtKB:Q6PML0 xref: UniProtKB:Q9BXG9 xref: UniProtKB:Q9H3M7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005849 ! TXNIP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071639 ! TXNIP_HUMAN-Phosphothreonine349 relationship: transforms_into CCO:B0071640 ! TXNIP_HUMAN-Phosphoserine361 [Term] id: CCO:B0002134 name: DSN1_HUMAN def: "Kinetochore-associated protein DSN1 homolog" [UniProtKB:Q9H410] xref: EMBL:AAH58899.1 xref: EMBL:BAB14564.1 xref: EMBL:BAC04024.1 xref: EMBL:CAC10099.2 xref: UniProtKB:Q5JW56 xref: UniProtKB:Q9H410 xref: UniProtKB:Q9H8P4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004513 ! DSN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011591 ! DSN1_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0011592 ! DSN1_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0011593 ! DSN1_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0064881 ! DSN1_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0064882 ! DSN1_HUMAN-Phosphoserine81 [Term] id: CCO:B0002135 name: PIGU_HUMAN def: "Phosphatidylinositol glycan anchor biosynthesis class U protein" [UniProtKB:Q9H490] synonym: "Cell division cycle protein 91-like 1" EXACT [UniProtKB:Q9H490] synonym: "GPI transamidase component PIG-U" EXACT [UniProtKB:Q9H490] synonym: "Protein CDC91-like 1" EXACT [UniProtKB:Q9H490] xref: EMBL:AAH30512.1 xref: EMBL:AAQ18022.1 xref: EMBL:AAQ89175.1 xref: EMBL:AAR23798.1 xref: EMBL:BAC11660.1 xref: EMBL:BAC53626.1 xref: EMBL:CAC14080.1 xref: UniProtKB:Q7Z489 xref: UniProtKB:Q8N2F2 xref: UniProtKB:Q9H490 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006366 ! PIGU_human relationship: has_function CCO:F0000426 ! GPI-anchor transamidase activity relationship: has_function CCO:F0005537 ! GPI anchor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: located_in CCO:C0001700 ! GPI-anchor transamidase complex relationship: participates_in CCO:P0002692 ! regulation of JAK-STAT cascade [Term] id: CCO:B0002137 name: RGC32_HUMAN def: "Response gene to complement 32 protein" [UniProtKB:Q9H4X1] synonym: "RGC-32" EXACT [UniProtKB:Q9H4X1] xref: EMBL:AAF04336.1 xref: EMBL:AAH66334.1 xref: EMBL:CAC13101.1 xref: UniProtKB:Q6NZ48 xref: UniProtKB:Q9H4X1 xref: UniProtKB:Q9UL69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005478 ! RGC32_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0013852 ! RGC32_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0013853 ! RGC32_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0013854 ! RGC32_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0013855 ! RGC32_HUMAN-Phosphothreonine111 [Term] id: CCO:B0002139 name: SUV92_HUMAN def: "Histone-lysine N-methyltransferase SUV39H2" [UniProtKB:Q9H5I1] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9H5I1] synonym: "H3-K9-HMTase 2" EXACT [UniProtKB:Q9H5I1] synonym: "Histone H3-K9 methyltransferase 2" EXACT [UniProtKB:Q9H5I1] synonym: "Lysine N-methyltransferase 1B" EXACT [UniProtKB:Q9H5I1] synonym: "Su(var)3-9 homolog 2" EXACT [UniProtKB:Q9H5I1] synonym: "Suppressor of variegation 3-9 homolog 2" EXACT [UniProtKB:Q9H5I1] xref: EMBL:AAH07754.1 xref: EMBL:AAH29360.1 xref: EMBL:BAB15645.1 xref: EMBL:CAD39146.1 xref: EMBL:CAG33653.1 xref: EMBL:CAI40028.1 xref: EMBL:CAI40032.1 xref: UniProtKB:Q5JSS5 xref: UniProtKB:Q6I9Y3 xref: UniProtKB:Q8ND06 xref: UniProtKB:Q9H5I1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005707 ! SUV39H2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005932 ! ewsr1-suv39h2 physical interaction relationship: participates_in CCO:I0008510 ! suv39h2-ube2v2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071003 ! SUV92_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0071004 ! SUV92_HUMAN-Phosphoserine382 relationship: transforms_into CCO:B0071005 ! SUV92_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0071006 ! SUV92_HUMAN-Phosphoserine388 [Term] id: CCO:B0002141 name: Q9H8U2_HUMAN def: "cDNA FLJ13223 fis, clone OVARC1000001, highly similar to Homo sapiens actin binding protein ABP620" [UniProtKB:Q9H8U2] xref: EMBL:BAB14509.1 xref: UniProtKB:Q9H8U2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0002142 name: CLSPN_HUMAN def: "Claspin" [UniProtKB:Q9HAW4] synonym: "hClaspin" EXACT [UniProtKB:Q9HAW4] synonym: "Hu-Claspin" EXACT [UniProtKB:Q9HAW4] xref: EMBL:AAG24515.1 xref: EMBL:AAH38991.1 xref: EMBL:AAH62215.1 xref: EMBL:CAH73807.1 xref: UniProtKB:Q5VYG0 xref: UniProtKB:Q6P6H5 xref: UniProtKB:Q8IWI1 xref: UniProtKB:Q9HAW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004372 ! CLSPN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0011267 ! CLSPN_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0011268 ! CLSPN_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0011269 ! CLSPN_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0011270 ! CLSPN_HUMAN-Phosphoserine762 relationship: transforms_into CCO:B0011271 ! CLSPN_HUMAN-Phosphoserine764 relationship: transforms_into CCO:B0011272 ! CLSPN_HUMAN-Phosphoserine833 relationship: transforms_into CCO:B0011273 ! CLSPN_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0011274 ! CLSPN_HUMAN-Phosphoserine846 relationship: transforms_into CCO:B0011275 ! CLSPN_HUMAN-Phosphoserine950 relationship: transforms_into CCO:B0011276 ! CLSPN_HUMAN-Phosphothreonine1287 relationship: transforms_into CCO:B0011277 ! CLSPN_HUMAN-Phosphoserine1289 relationship: transforms_into CCO:B0064392 ! CLSPN_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0064393 ! CLSPN_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0064394 ! CLSPN_HUMAN-Phosphoserine720 relationship: transforms_into CCO:B0064395 ! CLSPN_HUMAN-Phosphothreonine724 relationship: transforms_into CCO:B0064396 ! CLSPN_HUMAN-Phosphoserine808 relationship: transforms_into CCO:B0064397 ! CLSPN_HUMAN-Phosphoserine810 relationship: transforms_into CCO:B0064398 ! CLSPN_HUMAN-Phosphoserine1012 relationship: transforms_into CCO:B0064399 ! CLSPN_HUMAN-Phosphoserine1018 relationship: transforms_into CCO:B0064400 ! CLSPN_HUMAN-Phosphoserine1020 relationship: transforms_into CCO:B0064401 ! CLSPN_HUMAN-Phosphoserine1156 [Term] id: CCO:B0002143 name: SPC25_HUMAN def: "Kinetochore protein Spc25" [UniProtKB:Q9HBM1] synonym: "hSpc25" EXACT [UniProtKB:Q9HBM1] xref: EMBL:AAG09718.1 xref: EMBL:AAH22255.1 xref: EMBL:AAR88652.1 xref: EMBL:AAY24098.1 xref: EMBL:CAG33478.1 xref: UniProtKB:Q9HBM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005655 ! SPC25_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006064 ! kntc2-spbc25-1 physical interaction relationship: participates_in CCO:I0006065 ! kntc2-spbc25-2 physical interaction relationship: participates_in CCO:I0006224 ! spbc24-spbc25-4 physical interaction relationship: participates_in CCO:I0006764 ! kntc2-spbc24-3 physical interaction relationship: participates_in CCO:I0006765 ! kntc2-spbc25-4 physical interaction relationship: participates_in CCO:I0006908 ! kntc2-spbc25-3 physical interaction relationship: participates_in CCO:I0007169 ! kntc2-spbc24-4 physical interaction relationship: participates_in CCO:I0007301 ! kntc2-spbc24-1 physical interaction relationship: participates_in CCO:I0007302 ! spbc24-spbc25-3 physical interaction relationship: participates_in CCO:I0007464 ! spbc24-spbc25-1 physical interaction relationship: participates_in CCO:I0007465 ! spbc24-spbc25-2 physical interaction relationship: participates_in CCO:I0007816 ! spbc24-spbc25-5 colocalization relationship: participates_in CCO:I0007932 ! kntc2-spbc24-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002144 name: EMAL4_HUMAN def: "Echinoderm microtubule-associated protein-like 4" [UniProtKB:Q9HC35] synonym: "EMAP-4" EXACT [UniProtKB:Q9HC35] synonym: "Restrictedly overexpressed proliferation-associated protein" EXACT [UniProtKB:Q9HC35] synonym: "Ropp 120" EXACT [UniProtKB:Q9HC35] xref: EMBL:AAG09279.2 xref: EMBL:AAH23522.1 xref: EMBL:AAI04648.1 xref: EMBL:AAY14895.1 xref: EMBL:AAY15086.1 xref: EMBL:BAA91919.1 xref: UniProtKB:Q3SWW0 xref: UniProtKB:Q53R29 xref: UniProtKB:Q53TW8 xref: UniProtKB:Q6PJ45 xref: UniProtKB:Q9HC35 xref: UniProtKB:Q9NV40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004564 ! EML4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008355 ! arf4l-eml4 physical interaction relationship: participates_in CCO:I0008357 ! arih2-eml4 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0011680 ! EMAL4_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0011681 ! EMAL4_HUMAN-Phosphoserine144 relationship: transforms_into CCO:B0011682 ! EMAL4_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0011683 ! EMAL4_HUMAN-Phosphotyrosine226 relationship: transforms_into CCO:B0011684 ! EMAL4_HUMAN-Phosphotyrosine499 relationship: transforms_into CCO:B0011685 ! EMAL4_HUMAN-Phosphoserine502 relationship: transforms_into CCO:B0011686 ! EMAL4_HUMAN-Phosphothreonine899 relationship: transforms_into CCO:B0065050 ! EMAL4_HUMAN-Phosphoserine895 relationship: transforms_into CCO:B0065051 ! EMAL4_HUMAN-Phosphothreonine897 relationship: transforms_into CCO:B0065052 ! EMAL4_HUMAN-Phosphoserine903 relationship: transforms_into CCO:B0065053 ! EMAL4_HUMAN-Phosphothreonine909 relationship: transforms_into CCO:B0065054 ! EMAL4_HUMAN-Phosphothreonine921 relationship: transforms_into CCO:B0065055 ! EMAL4_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0065056 ! EMAL4_HUMAN-Phosphoserine942 relationship: transforms_into CCO:B0065057 ! EMAL4_HUMAN-Phosphoserine946 [Term] id: CCO:B0002145 name: NEK6_HUMAN def: "Serine/threonine-protein kinase Nek6" [UniProtKB:Q9HC98] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9HC98] synonym: "NimA-related protein kinase 6" EXACT [UniProtKB:Q9HC98] synonym: "Protein kinase SID6-1512" EXACT [UniProtKB:Q9HC98] xref: EMBL:AAG13417.1 xref: EMBL:AAH00101.2 xref: EMBL:AAH04174.2 xref: EMBL:AAH04209.2 xref: EMBL:AAH12761.1 xref: EMBL:BAA85045.1 xref: EMBL:BAG35899.1 xref: EMBL:CAG33372.1 xref: EMBL:CAG47018.1 xref: EMBL:CAH70247.1 xref: EMBL:CAH70254.1 xref: EMBL:CAI10876.1 xref: EMBL:CAI10883.1 xref: EMBL:EAW87579.1 xref: EMBL:EAW87581.1 xref: UniProtKB:Q5TBG3 xref: UniProtKB:Q5TBG9 xref: UniProtKB:Q6FG86 xref: UniProtKB:Q6IAR3 xref: UniProtKB:Q96E83 xref: UniProtKB:Q9HC98 xref: UniProtKB:Q9ULX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005178 ! NEK6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006459 ! pin1-nek6-1 physical interaction relationship: participates_in CCO:I0007509 ! pin1-nek6-2 physical interaction relationship: participates_in CCO:I0007510 ! pin1-nek6-3 colocalization relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002146 name: TF7L1_HUMAN def: "Transcription factor 7-like 1" [UniProtKB:Q9HCS4] synonym: "HMG box transcription factor 3" EXACT [UniProtKB:Q9HCS4] synonym: "TCF-3" EXACT [UniProtKB:Q9HCS4] xref: EMBL:AAH58894.1 xref: EMBL:AAY24094.1 xref: EMBL:BAB18185.1 xref: EMBL:CAB91064.1 xref: UniProtKB:Q53R97 xref: UniProtKB:Q6PD70 xref: UniProtKB:Q9HCS4 xref: UniProtKB:Q9NP00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005766 ! TCF7L1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000269 ! positive regulation of transcription from RNA polymerase II promoter, mitotic relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0002147 name: BRMS1_HUMAN def: "Breast cancer metastasis-suppressor 1" [UniProtKB:Q9HCU9] xref: EMBL:AAG00075.1 xref: EMBL:AAH09834.1 xref: EMBL:AAK69131.1 xref: UniProtKB:Q9HCU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004191 ! BRMS1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006821 ! brms1-hdac1 physical interaction relationship: participates_in CCO:I0006822 ! brms1-hdac2 physical interaction relationship: participates_in CCO:I0006823 ! brms1-hdac4 physical interaction relationship: participates_in CCO:I0006824 ! brms1-hdac5 physical interaction relationship: participates_in CCO:I0006825 ! brms1-hdac6 physical interaction relationship: participates_in CCO:I0006936 ! brms1-arid4a physical interaction relationship: participates_in CCO:I0006937 ! brms1-sds3 physical interaction relationship: participates_in CCO:I0006938 ! brms1-smarce1 physical interaction relationship: participates_in CCO:I0006939 ! brms1-taf1 physical interaction relationship: participates_in CCO:I0006940 ! brms1-nmi physical interaction relationship: participates_in CCO:I0006941 ! brms1-dnajb6 physical interaction relationship: participates_in CCO:I0006942 ! brms1-kpna5 physical interaction relationship: participates_in CCO:I0006943 ! brms1-hspa8 physical interaction relationship: participates_in CCO:I0007189 ! hdac1-brms1 physical interaction relationship: participates_in CCO:I0007190 ! hdac2-brms1 physical interaction relationship: participates_in CCO:I0007191 ! hdac3-brms1 physical interaction relationship: participates_in CCO:I0007192 ! hdac4-brms1 physical interaction relationship: participates_in CCO:I0007193 ! hdac5-brms1 physical interaction relationship: participates_in CCO:I0007194 ! hdac6-brms1 physical interaction relationship: participates_in CCO:I0007719 ! sds3-brms1 physical interaction relationship: participates_in CCO:I0007720 ! dnajb6-brms1 physical interaction relationship: participates_in CCO:I0007721 ! nmi-brms1 physical interaction relationship: participates_in CCO:I0007722 ! smarce1-brms1 physical interaction relationship: participates_in CCO:I0008202 ! brms1-eef1a1 physical interaction relationship: participates_in CCO:I0008203 ! brms1-rif1 physical interaction relationship: participates_in CCO:I0008391 ! golgb1-brms1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0002148 name: CHM1A_HUMAN def: "Charged multivesicular body protein 1a" [UniProtKB:Q9HD42] synonym: "CHMP1a" EXACT [UniProtKB:Q9HD42] synonym: "Chromatin-modifying protein 1a" EXACT [UniProtKB:Q9HD42] synonym: "hVps46-1" EXACT [UniProtKB:Q9HD42] synonym: "Vacuolar protein-sorting-associated protein 46-1" EXACT [UniProtKB:Q9HD42] synonym: "Vps46-1" EXACT [UniProtKB:Q9HD42] xref: EMBL:AAC50775.1 xref: EMBL:AAG01448.1 xref: EMBL:AAH10000.2 xref: EMBL:AAI32712.1 xref: EMBL:AAI32714.1 xref: EMBL:AAP35487.1 xref: EMBL:BAA07557.1 xref: UniProtKB:A2RU09 xref: UniProtKB:Q14468 xref: UniProtKB:Q15779 xref: UniProtKB:Q96G31 xref: UniProtKB:Q9HD42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004349 ! CHMP1A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001125 ! gene silencing relationship: participates_in CCO:P0002261 ! negative regulation of transcription by glucose relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0002149 name: PRM3_HUMAN def: "Protamine-3" [UniProtKB:Q9NNZ6] synonym: "Sperm protamine P3" EXACT [UniProtKB:Q9NNZ6] xref: EMBL:CAB92526.1 xref: UniProtKB:Q9NNZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005379 ! PRM3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation [Term] id: CCO:B0002150 name: PAR6A_HUMAN def: "Partitioning defective 6 homolog alpha" [UniProtKB:Q9NPB6] synonym: "PAR-6" EXACT [UniProtKB:Q9NPB6] synonym: "PAR-6 alpha" EXACT [UniProtKB:Q9NPB6] synonym: "PAR-6A" EXACT [UniProtKB:Q9NPB6] synonym: "PAR6C" EXACT [UniProtKB:Q9NPB6] synonym: "Tax interaction protein 40" EXACT [UniProtKB:Q9NPB6] synonym: "TIP-40" EXACT [UniProtKB:Q9NPB6] xref: EMBL:AAB84252.1 xref: EMBL:AAF71529.1 xref: EMBL:AAF75548.1 xref: EMBL:AAH15626.1 xref: EMBL:BAA96235.1 xref: EMBL:BAB16105.1 xref: EMBL:CAB85490.1 xref: UniProtKB:O14911 xref: UniProtKB:Q9NPB6 xref: UniProtKB:Q9NPJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005262 ! PARD6A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003531 ! Rho GTPase binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0005724 ! pard6a-prkci physical interaction relationship: participates_in CCO:I0005940 ! pard6a-prkcz physical interaction relationship: participates_in CCO:I0005988 ! pard6a-prkci-1 physical interaction relationship: participates_in CCO:I0005989 ! pard6a-prkcz-1 physical interaction relationship: participates_in CCO:I0005993 ! pard6a-rac1-2 physical interaction relationship: participates_in CCO:I0005994 ! pard6a-cdc42-4 physical interaction relationship: participates_in CCO:I0006238 ! pard6a-prkci-3 direct interaction relationship: participates_in CCO:I0006465 ! pard3-pard6a-1 physical interaction relationship: participates_in CCO:I0006466 ! pard6a-pard3-1 physical interaction relationship: participates_in CCO:I0006467 ! prcki-pard6-1 physical interaction relationship: participates_in CCO:I0006631 ! pard6a-tcp10-2 physical interaction relationship: participates_in CCO:I0006632 ! pard6a-cdc42-2 physical interaction relationship: participates_in CCO:I0006633 ! pard6a-tcp10-3 physical interaction relationship: participates_in CCO:I0006634 ! pard6a-cdc42-3 physical interaction relationship: participates_in CCO:I0006832 ! cdc42-pard6a-1 physical interaction relationship: participates_in CCO:I0006835 ! rac1-pard6a-1 physical interaction relationship: participates_in CCO:I0007200 ! pard3-pard6a-3 physical interaction relationship: participates_in CCO:I0007202 ! pard3-pard6a-2 physical interaction relationship: participates_in CCO:I0007203 ! pard6a-prkci-2 physical interaction relationship: participates_in CCO:I0007204 ! pard6a-par6b-1 physical interaction relationship: participates_in CCO:I0007205 ! pard6a-cdc42-5 physical interaction relationship: participates_in CCO:I0007206 ! prkci-pard6a-1 physical interaction relationship: participates_in CCO:I0007210 ! pard6a-mark4-1 physical interaction relationship: participates_in CCO:I0007213 ! pard6a-ywhah-1 physical interaction relationship: participates_in CCO:I0007214 ! pard6a-ywhaz-1 physical interaction relationship: participates_in CCO:I0007224 ! cdc42-pard6a-2 physical interaction relationship: participates_in CCO:I0007520 ! pard6a-prcki-1 physical interaction relationship: participates_in CCO:I0007521 ! prcki-pard6a-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002151 name: PLCB1_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1" [UniProtKB:Q9NQ66] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q9NQ66] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:Q9NQ66] synonym: "Phospholipase C-beta-1" EXACT [UniProtKB:Q9NQ66] synonym: "PLC-154" EXACT [UniProtKB:Q9NQ66] synonym: "PLC-beta-1" EXACT [UniProtKB:Q9NQ66] synonym: "PLC-I" EXACT [UniProtKB:Q9NQ66] xref: EMBL:AAF86613.1 xref: EMBL:AAH69420.1 xref: EMBL:BAA25507.3 xref: EMBL:BAB14641.1 xref: EMBL:CAB70666.1 xref: EMBL:CAB98142.1 xref: EMBL:CAB98143.1 xref: EMBL:CAI21973.1 xref: EMBL:CAI21974.1 xref: EMBL:CAI22175.1 xref: EMBL:CAI22830.1 xref: EMBL:CAI22831.1 xref: EMBL:CAI42238.1 xref: EMBL:CAI42239.1 xref: EMBL:CAI43121.1 xref: EMBL:CAI43122.1 xref: EMBL:CAI43151.1 xref: EMBL:CAI43152.1 xref: UniProtKB:O60325 xref: UniProtKB:Q5TFF7 xref: UniProtKB:Q5TGC9 xref: UniProtKB:Q8IV93 xref: UniProtKB:Q9BQW2 xref: UniProtKB:Q9H4H2 xref: UniProtKB:Q9H8H5 xref: UniProtKB:Q9NQ65 xref: UniProtKB:Q9NQ66 xref: UniProtKB:Q9NQH9 xref: UniProtKB:Q9NTH4 xref: UniProtKB:Q9UJP6 xref: UniProtKB:Q9UM26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005333 ! PLCB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0013556 ! PLCB1_HUMAN-Phosphothreonine333 relationship: transforms_into CCO:B0013557 ! PLCB1_HUMAN-Phosphotyrosine334 relationship: transforms_into CCO:B0013558 ! PLCB1_HUMAN-Phosphothreonine336 relationship: transforms_into CCO:B0013559 ! PLCB1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0013560 ! PLCB1_HUMAN-Phosphothreonine573 relationship: transforms_into CCO:B0013561 ! PLCB1_HUMAN-Phosphoserine887 relationship: transforms_into CCO:B0013562 ! PLCB1_HUMAN-N6-acetyllysine972 relationship: transforms_into CCO:B0013563 ! PLCB1_HUMAN-N6-acetyllysine976 [Term] id: CCO:B0002152 name: TF7L2_HUMAN def: "Transcription factor 7-like 2" [UniProtKB:Q9NQB0] synonym: "HMG box transcription factor 4" EXACT [UniProtKB:Q9NQB0] synonym: "hTCF-4" EXACT [UniProtKB:Q9NQB0] synonym: "T-cell-specific transcription factor 4" EXACT [UniProtKB:Q9NQB0] synonym: "TCF-4" EXACT [UniProtKB:Q9NQB0] xref: EMBL:AAH32656.1 xref: EMBL:BAA86225.1 xref: EMBL:CAA72166.2 xref: EMBL:CAB97212.1 xref: EMBL:CAB97213.1 xref: EMBL:CAB97214.1 xref: EMBL:CAB97215.1 xref: EMBL:CAB97216.1 xref: EMBL:CAB97217.1 xref: EMBL:CAB97218.1 xref: EMBL:CAB97219.1 xref: UniProtKB:O00185 xref: UniProtKB:Q9NQB0 xref: UniProtKB:Q9NQB1 xref: UniProtKB:Q9NQB2 xref: UniProtKB:Q9NQB3 xref: UniProtKB:Q9NQB4 xref: UniProtKB:Q9NQB5 xref: UniProtKB:Q9NQB6 xref: UniProtKB:Q9NQB7 xref: UniProtKB:Q9ULC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005767 ! TCF7L2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005971 ! ctnnb1-tcf7l2-8 direct interaction relationship: participates_in CCO:I0006051 ! tcf4-ctnnb1-1 direct interaction relationship: participates_in CCO:I0006235 ! ctnnb1-tcf7l2-7 direct interaction relationship: participates_in CCO:I0006264 ! tcf7l2-parp1-5 physical interaction relationship: participates_in CCO:I0006464 ! tcf7l2-parp1 physical interaction relationship: participates_in CCO:I0006550 ! tcf4-daxx-2 colocalization relationship: participates_in CCO:I0006912 ! tcf7l2-ctnnb1-2 physical interaction relationship: participates_in CCO:I0006913 ! tcf7l2-ctnnb1-4 physical interaction relationship: participates_in CCO:I0007011 ! tcf7l2-ctnnb1 physical interaction relationship: participates_in CCO:I0007054 ! tcf7l2-parp1-1 physical interaction relationship: participates_in CCO:I0007055 ! tcf7l2-g22p1 physical interaction relationship: participates_in CCO:I0007056 ! tcf7l2-ctnnb1-7 physical interaction relationship: participates_in CCO:I0007139 ! tcf4-daxx physical interaction relationship: participates_in CCO:I0007140 ! tcf4-daxx-1 physical interaction relationship: participates_in CCO:I0007141 ! daxx-tcf4 physical interaction relationship: participates_in CCO:I0007142 ! tcf4-ctnnb1 physical interaction relationship: participates_in CCO:I0007320 ! parp1-tcf7l2-1 physical interaction relationship: participates_in CCO:I0007321 ! g22p1-parp1 physical interaction relationship: participates_in CCO:I0007370 ! tcf4-daxx-3 physical interaction relationship: participates_in CCO:I0007482 ! tcf7l2-ctnnb1-8 physical interaction relationship: participates_in CCO:I0007483 ! g22p1-tcf7l2 physical interaction relationship: participates_in CCO:I0007517 ! tcf7l2-g22p1-1 physical interaction relationship: participates_in CCO:I0007699 ! ctnnb1-tcf7l2-2 physical interaction relationship: participates_in CCO:I0007700 ! ctnnb1-tcf7l2-3 physical interaction relationship: participates_in CCO:I0007701 ! ctnnb1-tcf7l2-4 physical interaction relationship: participates_in CCO:I0007702 ! ctnnb1-tcf7l2-5 physical interaction relationship: participates_in CCO:I0007703 ! ctnnb1-tcf7l2-6 physical interaction relationship: participates_in CCO:I0007704 ! jup-psen1-6 physical interaction relationship: participates_in CCO:I0007705 ! tcf7l2-ctnnb1-3 physical interaction relationship: participates_in CCO:I0007706 ! jup-psen1-7 physical interaction relationship: participates_in CCO:I0007803 ! tcf7l2-ctnnb1-1 physical interaction relationship: participates_in CCO:I0007804 ! tcf7l2-ctnnb1-5 physical interaction relationship: participates_in CCO:I0007805 ! tcf7l2-ctnnb1-6 physical interaction relationship: participates_in CCO:I0007806 ! jup-tcf7l2 physical interaction relationship: participates_in CCO:I0007807 ! jup-psen1-5 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001532 ! positive regulation of insulin secretion relationship: participates_in CCO:P0001608 ! regulation of hormone metabolic process relationship: participates_in CCO:P0003241 ! Wnt receptor signaling pathway through beta-catenin [Term] id: CCO:B0002153 name: CYLD_HUMAN def: "Probable ubiquitin carboxyl-terminal hydrolase CYLD" [UniProtKB:Q9NQC7] synonym: "Deubiquitinating enzyme CYLD" EXACT [UniProtKB:Q9NQC7] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q9NQC7] synonym: "Ubiquitin thioesterase CYLD" EXACT [UniProtKB:Q9NQC7] synonym: "Ubiquitin-specific-processing protease CYLD" EXACT [UniProtKB:Q9NQC7] xref: EMBL:AAF29029.1 xref: EMBL:AAH12342.1 xref: EMBL:BAA74872.2 xref: EMBL:CAB93533.1 xref: UniProtKB:O94934 xref: UniProtKB:Q7L3N6 xref: UniProtKB:Q96EH0 xref: UniProtKB:Q9NQC7 xref: UniProtKB:Q9NZX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004430 ! CYLD_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0011419 ! CYLD_HUMAN-Phosphoserine399 [Term] id: CCO:B0002154 name: INCE_HUMAN def: "Inner centromere protein" [UniProtKB:Q9NQS7] xref: EMBL:AAF87584.1 xref: EMBL:AAH98576.1 xref: EMBL:AAU04398.1 xref: EMBL:EAW74004.1 xref: UniProtKB:A8MQD2 xref: UniProtKB:Q5Y192 xref: UniProtKB:Q9NQS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004891 ! INCENP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006674 ! incenp-cbx5-1 physical interaction relationship: participates_in CCO:I0007394 ! incenp-cbx5-2 physical interaction relationship: participates_in CCO:I0007395 ! cbx5-incenp-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012381 ! INCE_HUMAN-Phosphotyrosine73 relationship: transforms_into CCO:B0012382 ! INCE_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0012383 ! INCE_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0012384 ! INCE_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0012385 ! INCE_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0012386 ! INCE_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0012387 ! INCE_HUMAN-Phosphothreonine199 relationship: transforms_into CCO:B0012388 ! INCE_HUMAN-Phosphothreonine213 relationship: transforms_into CCO:B0012389 ! INCE_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0012390 ! INCE_HUMAN-Phosphothreonine219 relationship: transforms_into CCO:B0012391 ! INCE_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0012392 ! INCE_HUMAN-Phosphothreonine239 relationship: transforms_into CCO:B0012393 ! INCE_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0012394 ! INCE_HUMAN-Phosphoserine269 relationship: transforms_into CCO:B0012395 ! INCE_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0012396 ! INCE_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0012397 ! INCE_HUMAN-Phosphothreonine292 relationship: transforms_into CCO:B0012398 ! INCE_HUMAN-Phosphothreonine294 relationship: transforms_into CCO:B0012399 ! INCE_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0012400 ! INCE_HUMAN-Phosphothreonine298 relationship: transforms_into CCO:B0012401 ! INCE_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0012402 ! INCE_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0012403 ! INCE_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0012404 ! INCE_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0012405 ! INCE_HUMAN-Phosphothreonine424 relationship: transforms_into CCO:B0012406 ! INCE_HUMAN-Phosphoserine481 relationship: transforms_into CCO:B0012412 ! INCE_HUMAN-Phosphoserine899 relationship: transforms_into CCO:B0048286 ! INCE_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0067100 ! INCE_HUMAN-Phosphothreonine145 relationship: transforms_into CCO:B0067101 ! INCE_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0067102 ! INCE_HUMAN-Phosphoserine446 relationship: transforms_into CCO:B0067103 ! INCE_HUMAN-Phosphothreonine507 relationship: transforms_into CCO:B0067104 ! INCE_HUMAN-Phosphothreonine509 relationship: transforms_into CCO:B0067105 ! INCE_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0067106 ! INCE_HUMAN-Phosphoserine514 relationship: transforms_into CCO:B0067107 ! INCE_HUMAN-Phosphoserine828 relationship: transforms_into CCO:B0067108 ! INCE_HUMAN-Phosphoserine831 relationship: transforms_into CCO:B0067109 ! INCE_HUMAN-Phosphothreonine832 relationship: transforms_into CCO:B0067110 ! INCE_HUMAN-Phosphothreonine892 relationship: transforms_into CCO:B0067111 ! INCE_HUMAN-Phosphoserine893 relationship: transforms_into CCO:B0067112 ! INCE_HUMAN-Phosphoserine894 relationship: transforms_into CCO:B0067113 ! INCE_HUMAN-Phosphoserine914 [Term] id: CCO:B0002155 name: ANLN_HUMAN def: "Actin-binding protein anillin" [UniProtKB:Q9NQW6] xref: EMBL:AAF75796.1 xref: EMBL:AAH34692.1 xref: EMBL:AAH70066.1 xref: EMBL:BAA91710.1 xref: EMBL:BAA91711.1 xref: EMBL:BAB14463.1 xref: EMBL:CAI56788.1 xref: UniProtKB:Q5CZ78 xref: UniProtKB:Q6NSK5 xref: UniProtKB:Q9H8Y4 xref: UniProtKB:Q9NQW6 xref: UniProtKB:Q9NVN9 xref: UniProtKB:Q9NVP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004062 ! ANLN_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000394 ! contractile ring relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010537 ! ANLN_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0010538 ! ANLN_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0010539 ! ANLN_HUMAN-Phosphothreonine194 relationship: transforms_into CCO:B0010540 ! ANLN_HUMAN-Phosphothreonine320 relationship: transforms_into CCO:B0010541 ! ANLN_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0010542 ! ANLN_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0010543 ! ANLN_HUMAN-Phosphothreonine368 relationship: transforms_into CCO:B0010544 ! ANLN_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0010545 ! ANLN_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0010546 ! ANLN_HUMAN-Phosphoserine485 relationship: transforms_into CCO:B0010547 ! ANLN_HUMAN-Phosphothreonine515 relationship: transforms_into CCO:B0010548 ! ANLN_HUMAN-Phosphoserine637 relationship: transforms_into CCO:B0010549 ! ANLN_HUMAN-Phosphoserine927 relationship: transforms_into CCO:B0048158 ! ANLN_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0048159 ! ANLN_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0048160 ! ANLN_HUMAN-Phosphoserine661 relationship: transforms_into CCO:B0065628 ! ANLN_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0065629 ! ANLN_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0065630 ! ANLN_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0065631 ! ANLN_HUMAN-Phosphothreonine364 relationship: transforms_into CCO:B0065632 ! ANLN_HUMAN-Phosphothreonine393 relationship: transforms_into CCO:B0065633 ! ANLN_HUMAN-Phosphothreonine397 relationship: transforms_into CCO:B0065634 ! ANLN_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0065635 ! ANLN_HUMAN-Phosphoserine553 relationship: transforms_into CCO:B0065636 ! ANLN_HUMAN-Phosphoserine658 relationship: transforms_into CCO:B0065637 ! ANLN_HUMAN-Phosphoserine664 relationship: transforms_into CCO:B0065638 ! ANLN_HUMAN-Phosphoserine792 [Term] id: CCO:B0002156 name: BIN3_HUMAN def: "Bridging integrator 3" [UniProtKB:Q9NQY0] xref: EMBL:AAF76218.1 xref: EMBL:AAH01223.1 xref: EMBL:AAH09824.1 xref: EMBL:BAA91603.1 xref: EMBL:BAB14751.1 xref: UniProtKB:Q9BVG2 xref: UniProtKB:Q9NQY0 xref: UniProtKB:Q9NVY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004164 ! BIN3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000454 ! barrier septum formation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002157 name: CP26B_HUMAN def: "Cytochrome P450 26B1" [UniProtKB:Q9NR63] synonym: "EC 1.14.-.-" EXACT [UniProtKB:Q9NR63] synonym: "P450 26A2" EXACT [UniProtKB:Q9NR63] synonym: "P450 retinoic acid-inactivating 2" EXACT [UniProtKB:Q9NR63] synonym: "P450RAI-2" EXACT [UniProtKB:Q9NR63] synonym: "Retinoic acid-metabolizing cytochrome" EXACT [UniProtKB:Q9NR63] xref: EMBL:AAF76003.1 xref: EMBL:AAH69443.1 xref: EMBL:AAI09206.1 xref: EMBL:AAY14690.1 xref: UniProtKB:Q32MC0 xref: UniProtKB:Q53TW1 xref: UniProtKB:Q9NP41 xref: UniProtKB:Q9NR63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004390 ! CYP26B1_human relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000131 ! male meiosis relationship: participates_in CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:B0002158 name: PDGFC_HUMAN def: "Platelet-derived growth factor C precursor" [UniProtKB:Q9NRA1] synonym: "Fallotein" EXACT [UniProtKB:Q9NRA1] synonym: "PDGF-C" EXACT [UniProtKB:Q9NRA1] synonym: "SCDGF" EXACT [UniProtKB:Q9NRA1] synonym: "Spinal cord-derived growth factor" EXACT [UniProtKB:Q9NRA1] synonym: "VEGF-E" EXACT [UniProtKB:Q9NRA1] xref: EMBL:AAF00049.1 xref: EMBL:AAF80597.1 xref: EMBL:AAK51637.1 xref: EMBL:AAQ88857.1 xref: EMBL:AAY40906.1 xref: EMBL:BAB03266.1 xref: EMBL:EAX04874.1 xref: UniProtKB:Q4W5M9 xref: UniProtKB:Q9NRA1 xref: UniProtKB:Q9UL22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006050 ! PDGFC_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0002159 name: LATS2_HUMAN def: "Serine/threonine-protein kinase LATS2" [UniProtKB:Q9NRM7] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9NRM7] synonym: "Kinase phosphorylated during mitosis protein" EXACT [UniProtKB:Q9NRM7] synonym: "Large tumor suppressor homolog 2" EXACT [UniProtKB:Q9NRM7] synonym: "Serine/threonine-protein kinase kpm" EXACT [UniProtKB:Q9NRM7] synonym: "Warts-like kinase" EXACT [UniProtKB:Q9NRM7] xref: EMBL:AAF80561.1 xref: EMBL:BAA92381.1 xref: EMBL:BAG36905.1 xref: EMBL:CAH71526.1 xref: EMBL:CAI15861.1 xref: EMBL:EAX08286.1 xref: UniProtKB:B1AM47 xref: UniProtKB:Q9NRM7 xref: UniProtKB:Q9P2X1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004972 ! LATS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012682 ! LATS2_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0067578 ! LATS2_HUMAN-Phosphothreonine279 relationship: transforms_into CCO:B0067579 ! LATS2_HUMAN-Phosphoserine380 [Term] id: CCO:B0002160 name: GRLF1_HUMAN def: "Glucocorticoid receptor DNA-binding factor 1" [UniProtKB:Q9NRY4] synonym: "Glucocorticoid receptor repression factor 1" EXACT [UniProtKB:Q9NRY4] synonym: "GRF-1" EXACT [UniProtKB:Q9NRY4] synonym: "p190-A" EXACT [UniProtKB:Q9NRY4] synonym: "Rho GAP p190A" EXACT [UniProtKB:Q9NRY4] xref: EMBL:AAA58618.1 xref: EMBL:AAF80386.1 xref: EMBL:BAB21813.2 xref: UniProtKB:Q14452 xref: UniProtKB:Q9C0E1 xref: UniProtKB:Q9NRY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004729 ! GRLF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0011975 ! GRLF1_HUMAN-Phosphothreonine685 relationship: transforms_into CCO:B0011976 ! GRLF1_HUMAN-Phosphoserine773 relationship: transforms_into CCO:B0011977 ! GRLF1_HUMAN-Phosphoserine980 relationship: transforms_into CCO:B0011978 ! GRLF1_HUMAN-Phosphotyrosine1105 relationship: transforms_into CCO:B0011979 ! GRLF1_HUMAN-Phosphoserine1134 relationship: transforms_into CCO:B0011980 ! GRLF1_HUMAN-Phosphoserine1179 relationship: transforms_into CCO:B0011981 ! GRLF1_HUMAN-Phosphoserine1195 relationship: transforms_into CCO:B0026378 ! GRLF1_HUMAN-Phosphoserine1150 relationship: transforms_into CCO:B0031328 ! GRLF1_HUMAN-Phosphotyrosine1087 relationship: transforms_into CCO:B0048271 ! GRLF1_HUMAN-Phosphoserine970 relationship: transforms_into CCO:B0066624 ! GRLF1_HUMAN-Phosphoserine589 relationship: transforms_into CCO:B0066625 ! GRLF1_HUMAN-Phosphothreonine963 relationship: transforms_into CCO:B0066626 ! GRLF1_HUMAN-Phosphoserine975 [Term] id: CCO:B0002161 name: HELLS_HUMAN def: "Lymphoid-specific helicase" [UniProtKB:Q9NRZ9] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9NRZ9] synonym: "Proliferation-associated SNF2-like protein" EXACT [UniProtKB:Q9NRZ9] synonym: "SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6" EXACT [UniProtKB:Q9NRZ9] xref: EMBL:AAF82262.1 xref: EMBL:AAG01987.1 xref: EMBL:AAH15477.1 xref: EMBL:AAH29381.1 xref: EMBL:AAH30963.1 xref: EMBL:AAH31004.1 xref: EMBL:BAD10845.1 xref: EMBL:BAD10846.1 xref: EMBL:BAD10847.1 xref: EMBL:BAD10848.1 xref: EMBL:BAD10849.1 xref: EMBL:BAD10850.1 xref: EMBL:BAD24805.1 xref: EMBL:BAE45737.1 xref: EMBL:CAD13191.1 xref: EMBL:CAD97978.1 xref: UniProtKB:Q3LID1 xref: UniProtKB:Q6I7N7 xref: UniProtKB:Q76H76 xref: UniProtKB:Q76H77 xref: UniProtKB:Q76H78 xref: UniProtKB:Q76H79 xref: UniProtKB:Q76H80 xref: UniProtKB:Q76H81 xref: UniProtKB:Q7Z397 xref: UniProtKB:Q7Z5X2 xref: UniProtKB:Q8N6P4 xref: UniProtKB:Q9H4P5 xref: UniProtKB:Q9NRZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004799 ! HELLS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: located_in CCO:C0002171 ! centromeric heterochromatin relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000652 ! methylation-dependent chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000918 ! maintenance of DNA methylation relationship: participates_in CCO:P0002724 ! lymphocyte proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002162 name: RASF1_HUMAN def: "Ras association domain-containing protein 1" [UniProtKB:Q9NS23] xref: EMBL:AAB67312.1 xref: EMBL:AAC16001.1 xref: EMBL:AAC70910.2 xref: EMBL:AAD44174.1 xref: EMBL:AAD44175.1 xref: EMBL:AAD44176.1 xref: EMBL:AAF35127.2 xref: EMBL:AAF35128.2 xref: EMBL:AAF35129.2 xref: EMBL:AAG10038.1 xref: EMBL:AAG10064.1 xref: UniProtKB:O14571 xref: UniProtKB:O60539 xref: UniProtKB:O60710 xref: UniProtKB:Q9HB04 xref: UniProtKB:Q9HB18 xref: UniProtKB:Q9NS22 xref: UniProtKB:Q9NS23 xref: UniProtKB:Q9UND4 xref: UniProtKB:Q9UND5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005429 ! RASSF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: participates_in CCO:I0006011 ! rassf1-xpa physical interaction relationship: participates_in CCO:I0008495 ! rassf1-nudt10 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:B0002164 name: GKN1_HUMAN def: "Gastrokine-1 precursor" [UniProtKB:Q9NS71] synonym: "18 kDa antrum mucosa protein" EXACT [UniProtKB:Q9NS71] synonym: "AMP-18" EXACT [UniProtKB:Q9NS71] synonym: "CA11 protein" EXACT [UniProtKB:Q9NS71] xref: EMBL:AAH59778.1 xref: EMBL:AAN75447.1 xref: EMBL:AAN75449.1 xref: EMBL:AAQ89409.1 xref: EMBL:BAA92433.1 xref: UniProtKB:Q8IUA9 xref: UniProtKB:Q9NS71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004700 ! GKN1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000985 ! secretory granule relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0002165 name: KIF15_HUMAN def: "Kinesin-like protein KIF15" [UniProtKB:Q9NS87] synonym: "hKLP2" EXACT [UniProtKB:Q9NS87] synonym: "Kinesin-like protein 2" EXACT [UniProtKB:Q9NS87] synonym: "Kinesin-like protein 7" EXACT [UniProtKB:Q9NS87] synonym: "Serologically defined breast cancer antigen NY-BR-62" EXACT [UniProtKB:Q9NS87] xref: EMBL:AAG48261.1 xref: EMBL:AAI17175.1 xref: EMBL:BAB03309.1 xref: EMBL:BAB55389.1 xref: EMBL:CAH10635.1 xref: UniProtKB:Q17RV9 xref: UniProtKB:Q69YL6 xref: UniProtKB:Q96JX7 xref: UniProtKB:Q9H280 xref: UniProtKB:Q9NS87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006053 ! KIF15_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000433 ! plus-end kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0008016 ! kif15-kiaa1377 physical interaction relationship: participates_in CCO:I0008126 ! kif15-chd3 physical interaction relationship: participates_in CCO:I0008127 ! kif15-vim physical interaction relationship: participates_in CCO:I0008403 ! kif15-map1lc3a physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0067358 ! KIF15_HUMAN-Phosphoserine568 [Term] id: CCO:B0002166 name: Q9NSH2_HUMAN def: "Septin" [UniProtKB:Q9NSH2] xref: EMBL:CAB89249.1 xref: UniProtKB:Q9NSH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006054 ! DKFZp547B243_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002168 name: SMC4_HUMAN def: "Structural maintenance of chromosomes protein 4" [UniProtKB:Q9NTJ3] synonym: "Chromosome-associated polypeptide C" EXACT [UniProtKB:Q9NTJ3] synonym: "hCAP-C" EXACT [UniProtKB:Q9NTJ3] synonym: "XCAP-C homolog" EXACT [UniProtKB:Q9NTJ3] xref: EMBL:AAC72361.1 xref: EMBL:BAA73535.1 xref: EMBL:CAB66811.1 xref: EMBL:CAD38803.1 xref: EMBL:EAW78639.1 xref: UniProtKB:A6NLT9 xref: UniProtKB:O95752 xref: UniProtKB:Q8NDL4 xref: UniProtKB:Q9NTJ3 xref: UniProtKB:Q9UNT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005629 ! SMC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006364 ! ikbkg-smc4l1 physical interaction relationship: participates_in CCO:I0007038 ! smc2l1-smc4l1 physical interaction relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014082 ! SMC4_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0014083 ! SMC4_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0014084 ! SMC4_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0014085 ! SMC4_HUMAN-Phosphoserine1056 relationship: transforms_into CCO:B0070618 ! SMC4_HUMAN-Phosphoserine27 [Term] id: CCO:B0002169 name: SEP11_HUMAN def: "Septin-11" [UniProtKB:Q9NVA2] xref: EMBL:AAH08083.3 xref: EMBL:AAH63615.1 xref: EMBL:BAA91853.1 xref: EMBL:BAB55250.1 xref: UniProtKB:Q7L4N1 xref: UniProtKB:Q96SP1 xref: UniProtKB:Q9NVA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005582 ! SEPT11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006897 ! sept5-sept11 physical interaction relationship: participates_in CCO:I0006899 ! sept11-sept5 physical interaction relationship: participates_in CCO:I0007372 ! sept5-sept11-1 physical interaction relationship: participates_in CCO:I0007376 ! sept11-sept5-1 physical interaction relationship: participates_in CCO:I0007794 ! sept5-sept11-2 direct interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013990 ! SEP11_HUMAN-N-acetylalanine2 [Term] id: CCO:B0002170 name: FANCI_HUMAN def: "Fanconi anemia group I protein" [UniProtKB:Q9NVI1] synonym: "Protein FANCI" EXACT [UniProtKB:Q9NVI1] xref: EMBL:AAH04277.1 xref: EMBL:AAI40770.1 xref: EMBL:ABQ63084.1 xref: EMBL:BAA91770.1 xref: EMBL:BAB47423.1 xref: EMBL:BAB55200.1 xref: UniProtKB:A5YMH4 xref: UniProtKB:A6NJZ0 xref: UniProtKB:Q96JN1 xref: UniProtKB:Q96ST0 xref: UniProtKB:Q9BT96 xref: UniProtKB:Q9NVI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004612 ! FANCI_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011844 ! FANCI_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0011845 ! FANCI_HUMAN-Phosphoserine556 relationship: transforms_into CCO:B0011846 ! FANCI_HUMAN-Phosphoserine730 relationship: transforms_into CCO:B0011847 ! FANCI_HUMAN-Phosphothreonine952 relationship: transforms_into CCO:B0011848 ! FANCI_HUMAN-Phosphoserine1121 relationship: transforms_into CCO:B0048259 ! FANCI_HUMAN-Phosphotyrosine215 [Term] id: CCO:B0002171 name: AKIP_HUMAN def: "Aurora kinase A-interacting protein" [UniProtKB:Q9NWT8] synonym: "AURKA-interacting protein" EXACT [UniProtKB:Q9NWT8] xref: EMBL:AAH22808.1 xref: EMBL:AAH62333.1 xref: EMBL:BAA91289.1 xref: EMBL:CAI23191.1 xref: UniProtKB:Q5TA36 xref: UniProtKB:Q8TBD3 xref: UniProtKB:Q9NWT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004044 ! AURKAIP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006704 ! akip-stk6-1 physical interaction relationship: participates_in CCO:I0007077 ! akip-stk6-2 physical interaction relationship: participates_in CCO:P0000250 ! negative regulation of mitosis relationship: participates_in CCO:P0002579 ! positive regulation of proteolysis [Term] id: CCO:B0002172 name: TXN4B_HUMAN def: "Thioredoxin-like protein 4B" [UniProtKB:Q9NX01] synonym: "Dim1-like protein" EXACT [UniProtKB:Q9NX01] xref: EMBL:AAH09646.1 xref: EMBL:AAS68520.1 xref: EMBL:BAA91224.1 xref: EMBL:CAG33521.1 xref: UniProtKB:Q9NX01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005848 ! TXNL4B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0071635 ! TXN4B_HUMAN-Phosphoserine132 [Term] id: CCO:B0002173 name: NDE1_HUMAN def: "Nuclear distribution protein nudE homolog 1" [UniProtKB:Q9NXR1] synonym: "NudE" EXACT [UniProtKB:Q9NXR1] xref: EMBL:AAH01421.1 xref: EMBL:AAH33900.1 xref: EMBL:BAA90949.1 xref: UniProtKB:Q49AQ2 xref: UniProtKB:Q9NXR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005163 ! NDE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000300 ! centrosome duplication relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013130 ! NDE1_HUMAN-Phosphothreonine246 relationship: transforms_into CCO:B0013131 ! NDE1_HUMAN-Phosphotyrosine279 relationship: transforms_into CCO:B0013132 ! NDE1_HUMAN-Phosphoserine282 relationship: transforms_into CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0013134 ! NDE1_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0048333 ! NDE1_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0048334 ! NDE1_HUMAN-Phosphothreonine215 relationship: transforms_into CCO:B0048335 ! NDE1_HUMAN-Phosphothreonine228 relationship: transforms_into CCO:B0068522 ! NDE1_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0068523 ! NDE1_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0068524 ! NDE1_HUMAN-Phosphothreonine240 relationship: transforms_into CCO:B0068525 ! NDE1_HUMAN-Phosphothreonine243 [Term] id: CCO:B0002174 name: BTG4_HUMAN def: "Protein BTG4" [UniProtKB:Q9NY30] synonym: "BTG family member 4" EXACT [UniProtKB:Q9NY30] synonym: "Protein PC3b" EXACT [UniProtKB:Q9NY30] xref: EMBL:CAB69821.1 xref: UniProtKB:Q9NY30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004197 ! BTG4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0002175 name: NSMA2_HUMAN def: "Sphingomyelin phosphodiesterase 3" [UniProtKB:Q9NY59] synonym: "EC 3.1.4.12" EXACT [UniProtKB:Q9NY59] synonym: "Neutral sphingomyelinase 2" EXACT [UniProtKB:Q9NY59] synonym: "Neutral sphingomyelinase II" EXACT [UniProtKB:Q9NY59] synonym: "nSMase-2" EXACT [UniProtKB:Q9NY59] synonym: "nSMase2" EXACT [UniProtKB:Q9NY59] xref: EMBL:AAI12239.1 xref: EMBL:CAB92964.1 xref: UniProtKB:Q2M1S8 xref: UniProtKB:Q9NY59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005217 ! SMPD3_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001127 ! sphingomyelin phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000019 ! Golgi cis cisterna relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008235 ! smpd3-med31 physical interaction relationship: participates_in CCO:I0008236 ! smpd3-cops6 physical interaction relationship: participates_in CCO:I0008237 ! smpd3-crmp1 physical interaction relationship: participates_in CCO:I0008238 ! smpd3-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0008239 ! smpd3-g22p1 physical interaction relationship: participates_in CCO:I0008240 ! smpd3-gdf9 physical interaction relationship: participates_in CCO:I0008241 ! smpd3-rif1 physical interaction relationship: participates_in CCO:I0008242 ! smpd3-setdb1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0002176 name: SPHK1_HUMAN def: "Sphingosine kinase 1" [UniProtKB:Q9NYA1] synonym: "EC 2.7.1.91" EXACT [UniProtKB:Q9NYA1] synonym: "SK 1" EXACT [UniProtKB:Q9NYA1] synonym: "SPK 1" EXACT [UniProtKB:Q9NYA1] xref: EMBL:AAF73423.1 xref: EMBL:AAF73470.1 xref: EMBL:AAG01980.1 xref: EMBL:AAH14439.1 xref: EMBL:AAH30553.1 xref: EMBL:BAB14028.1 xref: EMBL:BAB14558.1 xref: EMBL:BAF84983.1 xref: EMBL:CAB92131.1 xref: EMBL:EAW89392.1 xref: UniProtKB:Q8N632 xref: UniProtKB:Q9HD92 xref: UniProtKB:Q9NY70 xref: UniProtKB:Q9NYA1 xref: UniProtKB:Q9NYL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005660 ! SPHK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0001254 ! positive regulation of cell growth relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: transforms_into CCO:B0070798 ! SPHK1_HUMAN-Phosphothreonine193 [Term] id: CCO:B0002177 name: APC11_HUMAN def: "Anaphase-promoting complex subunit 11" [UniProtKB:Q9NYG5] synonym: "APC11" EXACT [UniProtKB:Q9NYG5] synonym: "Cyclosome subunit 11" EXACT [UniProtKB:Q9NYG5] synonym: "Hepatocellular carcinoma-associated RING finger protein" EXACT [UniProtKB:Q9NYG5] xref: EMBL:AAF36134.1 xref: EMBL:AAF65816.1 xref: EMBL:AAH00607.2 xref: EMBL:AAH66308.1 xref: EMBL:AAH95454.1 xref: EMBL:AAI04642.1 xref: EMBL:AAL95694.1 xref: UniProtKB:Q502X9 xref: UniProtKB:Q9BW64 xref: UniProtKB:Q9NYG5 xref: UniProtKB:Q9P0R2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004079 ! ANAPC11_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002178 name: MLTK_HUMAN def: "Mitogen-activated protein kinase kinase kinase MLT" [UniProtKB:Q9NYL2] synonym: "Cervical cancer suppressor gene 4 protein" EXACT [UniProtKB:Q9NYL2] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q9NYL2] synonym: "HCCS-4" EXACT [UniProtKB:Q9NYL2] synonym: "Leucine zipper- and sterile alpha motif-containing kinase" EXACT [UniProtKB:Q9NYL2] synonym: "Mixed lineage kinase-related kinase" EXACT [UniProtKB:Q9NYL2] synonym: "MLK-like mitogen-activated protein triple kinase" EXACT [UniProtKB:Q9NYL2] synonym: "MLK-related kinase" EXACT [UniProtKB:Q9NYL2] synonym: "MRK" EXACT [UniProtKB:Q9NYL2] synonym: "Sterile alpha motif- and leucine zipper-containing kinase AZK" EXACT [UniProtKB:Q9NYL2] xref: EMBL:AAF63490.1 xref: EMBL:AAF65822.1 xref: EMBL:AAH01401.1 xref: EMBL:AAK11615.1 xref: EMBL:AAL85891.1 xref: EMBL:AAL85892.1 xref: EMBL:AAO33376.1 xref: EMBL:AAX82002.1 xref: EMBL:AAX93067.1 xref: EMBL:BAB12040.1 xref: EMBL:BAB16444.1 xref: EMBL:BAB16445.1 xref: EMBL:BAD92211.1 xref: UniProtKB:Q53SX1 xref: UniProtKB:Q580W8 xref: UniProtKB:Q59GY5 xref: UniProtKB:Q86YW8 xref: UniProtKB:Q9HCC4 xref: UniProtKB:Q9HCC5 xref: UniProtKB:Q9HDD2 xref: UniProtKB:Q9NYE9 xref: UniProtKB:Q9NYL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005105 ! MLTK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005850 ! mltk-znf567 physical interaction relationship: participates_in CCO:I0007864 ! mltk-mltk-1 acetylation relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000008 ! DNA damage checkpoint relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000410 ! activation of MAPKK activity relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0012964 ! MLTK_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0012965 ! MLTK_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0012966 ! MLTK_HUMAN-Phosphoserine635 relationship: transforms_into CCO:B0012967 ! MLTK_HUMAN-Phosphoserine637 relationship: transforms_into CCO:B0012968 ! MLTK_HUMAN-Phosphothreonine639 relationship: transforms_into CCO:B0036016 ! MLTK_HUMAN-Phosphoserine633 relationship: transforms_into CCO:B0048328 ! MLTK_HUMAN-Phosphoserine591 relationship: transforms_into CCO:B0048329 ! MLTK_HUMAN-Phosphoserine593 relationship: transforms_into CCO:B0048330 ! MLTK_HUMAN-Phosphoserine599 relationship: transforms_into CCO:B0068236 ! MLTK_HUMAN-Phosphothreonine628 relationship: transforms_into CCO:B0068237 ! MLTK_HUMAN-Phosphoserine727 relationship: transforms_into CCO:B0068238 ! MLTK_HUMAN-Phosphoserine733 [Term] id: CCO:B0002179 name: PLK2_HUMAN def: "Serine/threonine-protein kinase PLK2" [UniProtKB:Q9NYY3] synonym: "EC 2.7.11.21" EXACT [UniProtKB:Q9NYY3] synonym: "PLK-2" EXACT [UniProtKB:Q9NYY3] synonym: "Polo-like kinase 1" EXACT [UniProtKB:Q9NYY3] synonym: "Serine/threonine-protein kinase SNK" EXACT [UniProtKB:Q9NYY3] synonym: "Serum-inducible kinase" EXACT [UniProtKB:Q9NYY3] xref: EMBL:AAC14573.1 xref: EMBL:AAD00575.1 xref: EMBL:AAF62897.1 xref: EMBL:AAH13879.1 xref: UniProtKB:O60679 xref: UniProtKB:Q96CV7 xref: UniProtKB:Q9NYY3 xref: UniProtKB:Q9UE61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005338 ! PLK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008410 ! mpp3-plk2 physical interaction relationship: participates_in CCO:I0008417 ! plk2-ikbkap physical interaction relationship: participates_in CCO:I0008468 ! dlgap4-plk2 physical interaction relationship: participates_in CCO:P0000038 ! mitotic cell cycle relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0002180 name: GTSE1_HUMAN def: "G2 and S phase-expressed protein 1" [UniProtKB:Q9NYZ3] synonym: "B99 homolog" EXACT [UniProtKB:Q9NYZ3] xref: EMBL:AAF31459.1 xref: EMBL:AAH06325.1 xref: EMBL:AAH75828.1 xref: EMBL:BAD96526.1 xref: EMBL:BAG37928.1 xref: EMBL:CAJ86449.1 xref: EMBL:CAQ09324.1 xref: EMBL:CAQ10552.1 xref: UniProtKB:B0QYM3 xref: UniProtKB:Q20WK2 xref: UniProtKB:Q53GX5 xref: UniProtKB:Q5R3I6 xref: UniProtKB:Q6DHX4 xref: UniProtKB:Q9BRE0 xref: UniProtKB:Q9NYZ3 xref: UniProtKB:Q9UGZ9 xref: UniProtKB:Q9Y557 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004739 ! GTSE1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000439 ! cytoplasmic microtubule relationship: participates_in CCO:P0000015 ! G2 phase of mitotic cell cycle relationship: participates_in CCO:P0000065 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest relationship: transforms_into CCO:B0011990 ! GTSE1_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0011991 ! GTSE1_HUMAN-Phosphoserine494 relationship: transforms_into CCO:B0011992 ! GTSE1_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0011993 ! GTSE1_HUMAN-Phosphoserine501 relationship: transforms_into CCO:B0011994 ! GTSE1_HUMAN-Phosphoserine504 relationship: transforms_into CCO:B0011995 ! GTSE1_HUMAN-Phosphoserine536 relationship: transforms_into CCO:B0011996 ! GTSE1_HUMAN-Phosphoserine575 relationship: transforms_into CCO:B0011997 ! GTSE1_HUMAN-Phosphoserine580 relationship: transforms_into CCO:B0011998 ! GTSE1_HUMAN-Phosphoserine592 relationship: transforms_into CCO:B0048273 ! GTSE1_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0066658 ! GTSE1_HUMAN-Phosphoserine477 relationship: transforms_into CCO:B0066659 ! GTSE1_HUMAN-Phosphothreonine479 relationship: transforms_into CCO:B0066660 ! GTSE1_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0066661 ! GTSE1_HUMAN-Phosphoserine509 relationship: transforms_into CCO:B0066662 ! GTSE1_HUMAN-Phosphothreonine513 relationship: transforms_into CCO:B0066663 ! GTSE1_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0066664 ! GTSE1_HUMAN-Phosphoserine520 relationship: transforms_into CCO:B0066665 ! GTSE1_HUMAN-Phosphothreonine526 [Term] id: CCO:B0002181 name: WWOX_HUMAN def: "WW domain-containing oxidoreductase" [UniProtKB:Q9NZC7] synonym: "EC 1.1.1.-" EXACT [UniProtKB:Q9NZC7] synonym: "Fragile site FRA16D oxidoreductase" EXACT [UniProtKB:Q9NZC7] xref: EMBL:AAF27049.1 xref: EMBL:AAF27050.1 xref: EMBL:AAF78197.1 xref: EMBL:AAF82053.1 xref: EMBL:AAF82054.1 xref: EMBL:AAF82055.1 xref: EMBL:AAF82056.1 xref: EMBL:AAH03184.1 xref: EMBL:AAK81727.1 xref: EMBL:AAK81728.1 xref: EMBL:AAL05449.1 xref: EMBL:AAL05450.1 xref: EMBL:AAL05451.1 xref: EMBL:AAP36113.1 xref: EMBL:AAP94227.1 xref: UniProtKB:Q5MYT5 xref: UniProtKB:Q96KM3 xref: UniProtKB:Q96RF2 xref: UniProtKB:Q9BTT8 xref: UniProtKB:Q9NPC9 xref: UniProtKB:Q9NRF4 xref: UniProtKB:Q9NRF5 xref: UniProtKB:Q9NRF6 xref: UniProtKB:Q9NRK1 xref: UniProtKB:Q9NZC5 xref: UniProtKB:Q9NZC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005936 ! WWOX_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_function CCO:F0007309 ! cofactor binding relationship: has_function CCO:F0007988 ! coenzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0014703 ! WWOX_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0014704 ! WWOX_HUMAN-Phosphotyrosine33 [Term] id: CCO:B0002182 name: SH3B4_HUMAN def: "SH3 domain-binding protein 4" [UniProtKB:Q9P0V3] synonym: "EH-binding protein 10" EXACT [UniProtKB:Q9P0V3] synonym: "Transferrin receptor-trafficking protein" EXACT [UniProtKB:Q9P0V3] xref: EMBL:AAD01551.1 xref: EMBL:AAF33022.1 xref: EMBL:AAH57396.1 xref: EMBL:AAY14916.1 xref: EMBL:AAY24025.1 xref: EMBL:ABB18377.1 xref: UniProtKB:O95082 xref: UniProtKB:Q309A3 xref: UniProtKB:Q53QD0 xref: UniProtKB:Q53TD1 xref: UniProtKB:Q9P0V3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005606 ! SH3BP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0014052 ! SH3B4_HUMAN-Phosphoserine637 relationship: transforms_into CCO:B0070474 ! SH3B4_HUMAN-Phosphoserine246 [Term] id: CCO:B0002183 name: SEP10_HUMAN def: "Septin-10" [UniProtKB:Q9P0V9] xref: EMBL:AAF67469.1 xref: EMBL:AAH20502.1 xref: EMBL:AAH50345.2 xref: EMBL:AAY24142.1 xref: EMBL:BAB13873.1 xref: UniProtKB:Q86VP5 xref: UniProtKB:Q9HAH6 xref: UniProtKB:Q9P0V9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005581 ! SEPT10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0070371 ! SEP10_HUMAN-Phosphoserine451 [Term] id: CCO:B0002184 name: HM20B_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related" [UniProtKB:Q9P0W2] synonym: "BRCA2-associated factor 35" EXACT [UniProtKB:Q9P0W2] synonym: "HMG box-containing protein 20B" EXACT [UniProtKB:Q9P0W2] synonym: "SMARCE1-related protein" EXACT [UniProtKB:Q9P0W2] synonym: "Sox-like transcriptional factor" EXACT [UniProtKB:Q9P0W2] synonym: "Structural DNA-binding protein BRAF35" EXACT [UniProtKB:Q9P0W2] xref: EMBL:AAC26860.1 xref: EMBL:AAC62837.1 xref: EMBL:AAF66707.1 xref: EMBL:AAF76253.1 xref: EMBL:AAG01174.1 xref: EMBL:AAG60060.1 xref: EMBL:AAH02552.1 xref: EMBL:AAH03505.2 xref: EMBL:AAH04408.2 xref: EMBL:AAH21585.1 xref: EMBL:BAC03510.1 xref: EMBL:CAB90809.2 xref: EMBL:CAG33035.1 xref: UniProtKB:Q6IBP8 xref: UniProtKB:Q8NBD5 xref: UniProtKB:Q9HD21 xref: UniProtKB:Q9P0W2 xref: UniProtKB:Q9Y491 xref: UniProtKB:Q9Y4A2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004811 ! HMG20B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008118 ! hmg20b-vim physical interaction relationship: participates_in CCO:I0008395 ! hmg20b-hnrpl physical interaction relationship: participates_in CCO:I0008396 ! hmg20b-tacc2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0002185 name: PIM2_HUMAN def: "Serine/threonine-protein kinase Pim-2" [UniProtKB:Q9P1W9] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9P1W9] synonym: "Pim-2h" EXACT [UniProtKB:Q9P1W9] xref: EMBL:AAC78506.1 xref: EMBL:AAH18111.1 xref: EMBL:BAA95613.1 xref: UniProtKB:Q99739 xref: UniProtKB:Q9P1W9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005315 ! PIM2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005760 ! cutc-pim2 physical interaction relationship: participates_in CCO:I0006647 ! pim2-atxn1 physical interaction relationship: participates_in CCO:I0008397 ! hnrph3-pim2 physical interaction relationship: participates_in CCO:I0008412 ! ndufb8-pim2 physical interaction relationship: participates_in CCO:I0008473 ! fbxo18-pim2 physical interaction relationship: participates_in CCO:I0008501 ! rpl21-pim2 physical interaction relationship: participates_in CCO:P0000131 ! male meiosis relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000844 ! apoptotic mitochondrial changes relationship: transforms_into CCO:B0013512 ! PIM2_HUMAN-Phosphothreonine195 relationship: transforms_into CCO:B0013513 ! PIM2_HUMAN-Phosphoserine204 [Term] id: CCO:B0002186 name: RCC2_HUMAN def: "Protein RCC2" [UniProtKB:Q9P258] synonym: "RCC1-like protein TD-60" EXACT [UniProtKB:Q9P258] synonym: "Telophase disk protein of 60 kDa" EXACT [UniProtKB:Q9P258] xref: EMBL:AAH04933.1 xref: EMBL:AAH42141.1 xref: EMBL:AAH53908.1 xref: EMBL:BAA95994.1 xref: EMBL:CAB94882.1 xref: EMBL:CAD13148.1 xref: UniProtKB:Q8IVL9 xref: UniProtKB:Q9BSN6 xref: UniProtKB:Q9NPV8 xref: UniProtKB:Q9P258 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005457 ! RCC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013810 ! RCC2_HUMAN-Phosphothreonine20 relationship: transforms_into CCO:B0013811 ! RCC2_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0013812 ! RCC2_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0013813 ! RCC2_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0013814 ! RCC2_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0013815 ! RCC2_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0013816 ! RCC2_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0013817 ! RCC2_HUMAN-Phosphoserine347 [Term] id: CCO:B0002187 name: BCCIP_HUMAN def: "BRCA2 and CDKN1A-interacting protein" [UniProtKB:Q9P287] synonym: "P21- and CDK-associated protein 1" EXACT [UniProtKB:Q9P287] synonym: "Protein TOK-1" EXACT [UniProtKB:Q9P287] xref: EMBL:AAH09771.1 xref: EMBL:AAL55436.1 xref: EMBL:AAL55438.1 xref: EMBL:AAL55439.1 xref: EMBL:AAL55440.1 xref: EMBL:BAA92927.1 xref: EMBL:BAA92928.1 xref: EMBL:CAD39118.1 xref: EMBL:CAI12091.1 xref: EMBL:CAI12092.1 xref: EMBL:CAI12093.1 xref: UniProtKB:Q8ND15 xref: UniProtKB:Q96GC4 xref: UniProtKB:Q9P287 xref: UniProtKB:Q9P288 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004149 ! BCCIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0010769 ! BCCIP_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0010770 ! BCCIP_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0010771 ! BCCIP_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0010772 ! BCCIP_HUMAN-Phosphoserine115 [Term] id: CCO:B0002188 name: RHG20_HUMAN def: "Rho GTPase-activating protein 20" [UniProtKB:Q9P2F6] synonym: "Rho-type GTPase-activating protein 20" EXACT [UniProtKB:Q9P2F6] xref: EMBL:AAH39340.1 xref: EMBL:AAS45466.1 xref: EMBL:AAS45467.1 xref: EMBL:AAS45468.1 xref: EMBL:AAS45469.1 xref: EMBL:AAS45470.1 xref: EMBL:BAA92629.1 xref: UniProtKB:Q6RJU1 xref: UniProtKB:Q6RJU2 xref: UniProtKB:Q6RJU3 xref: UniProtKB:Q6RJU5 xref: UniProtKB:Q8IXS1 xref: UniProtKB:Q9P2F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005483 ! ARHGAP20_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0002189 name: DEC1_HUMAN def: "Deleted in esophageal cancer 1" [UniProtKB:Q9P2X7] synonym: "Candidate tumor suppressor CTS9" EXACT [UniProtKB:Q9P2X7] xref: EMBL:BAA96242.1 xref: EMBL:CAI16660.1 xref: UniProtKB:Q9P2X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004461 ! DEC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0002192 name: HDAC6_HUMAN def: "Histone deacetylase 6" [UniProtKB:Q9UBN7] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q9UBN7] synonym: "HD6" EXACT [UniProtKB:Q9UBN7] xref: EMBL:AAD29048.1 xref: EMBL:BAA74924.2 xref: EMBL:CAA09893.1 xref: UniProtKB:O94975 xref: UniProtKB:Q96CY0 xref: UniProtKB:Q9UBN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004791 ! HDAC6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006437 ! relb-hdac6 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006513 ! sirt2-hdac6-2 colocalization relationship: participates_in CCO:I0006708 ! sirt2-hdac6-1 physical interaction relationship: participates_in CCO:I0006825 ! brms1-hdac6 physical interaction relationship: participates_in CCO:I0006950 ! hdac6-hdac11-1 physical interaction relationship: participates_in CCO:I0007194 ! hdac6-brms1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012168 ! HDAC6_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0012169 ! HDAC6_HUMAN-Phosphothreonine30 [Term] id: CCO:B0002193 name: KS6B2_HUMAN def: "Ribosomal protein S6 kinase beta-2" [UniProtKB:Q9UBS0] synonym: "70 kDa ribosomal protein S6 kinase 2" EXACT [UniProtKB:Q9UBS0] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UBS0] synonym: "p70 ribosomal S6 kinase beta" EXACT [UniProtKB:Q9UBS0] synonym: "p70 S6 kinase beta" EXACT [UniProtKB:Q9UBS0] synonym: "p70 S6Kbeta" EXACT [UniProtKB:Q9UBS0] synonym: "p70-beta" EXACT [UniProtKB:Q9UBS0] synonym: "p70-S6KB" EXACT [UniProtKB:Q9UBS0] synonym: "S6 kinase-related kinase" EXACT [UniProtKB:Q9UBS0] synonym: "S6K-beta" EXACT [UniProtKB:Q9UBS0] synonym: "S6K-beta 2" EXACT [UniProtKB:Q9UBS0] synonym: "S6K2" EXACT [UniProtKB:Q9UBS0] synonym: "Serine/threonine-protein kinase 14 beta" EXACT [UniProtKB:Q9UBS0] synonym: "SRK" EXACT [UniProtKB:Q9UBS0] xref: EMBL:AAD20990.1 xref: EMBL:AAD46063.1 xref: EMBL:AAH00094.3 xref: EMBL:BAA34402.1 xref: EMBL:BAA37145.1 xref: UniProtKB:O94809 xref: UniProtKB:Q9UBS0 xref: UniProtKB:Q9UEC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004962 ! RPS6KB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002225 ! protein kinase B signaling cascade relationship: transforms_into CCO:B0012645 ! KS6B2_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0012646 ! KS6B2_HUMAN-Phosphoserine356 [Term] id: CCO:B0002194 name: DBF4A_HUMAN def: "Protein DBF4 homolog A" [UniProtKB:Q9UBU7] synonym: "Activator of S phase kinase" EXACT [UniProtKB:Q9UBU7] synonym: "Chiffon homolog A" EXACT [UniProtKB:Q9UBU7] synonym: "DBF4-type zinc finger-containing protein 1" EXACT [UniProtKB:Q9UBU7] xref: EMBL:AAD41911.1 xref: EMBL:AAD45357.1 xref: EMBL:AAH36045.1 xref: EMBL:AAH47693.1 xref: EMBL:AAS07418.1 xref: EMBL:AAS07442.1 xref: EMBL:BAA78326.1 xref: EMBL:BAA78327.1 xref: EMBL:BAF85258.1 xref: EMBL:EAL24170.1 xref: EMBL:EAW76930.1 xref: UniProtKB:A4D1D8 xref: UniProtKB:A8K954 xref: UniProtKB:O75226 xref: UniProtKB:Q75MS6 xref: UniProtKB:Q75N01 xref: UniProtKB:Q9UBU7 xref: UniProtKB:Q9Y2M6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004441 ! DBF4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006497 ! lsm8-ask/h37_(hudbf4 physical interaction relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0032839 ! DBF4A_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0032840 ! DBF4A_HUMAN-Phosphothreonine535 relationship: transforms_into CCO:B0032841 ! DBF4A_HUMAN-Phosphoserine539 relationship: transforms_into CCO:B0064633 ! DBF4A_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0064634 ! DBF4A_HUMAN-Phosphoserine359 [Term] id: CCO:B0002196 name: DAXX_HUMAN def: "Death domain-associated protein 6" [UniProtKB:Q9UER7] synonym: "Daxx" EXACT [UniProtKB:Q9UER7] synonym: "EAP1" EXACT [UniProtKB:Q9UER7] synonym: "ETS1-associated protein 1" EXACT [UniProtKB:Q9UER7] synonym: "Fas death domain-associated protein" EXACT [UniProtKB:Q9UER7] synonym: "hDaxx" EXACT [UniProtKB:Q9UER7] xref: EMBL:AAB63043.1 xref: EMBL:AAB66585.2 xref: EMBL:AAB92671.1 xref: EMBL:AAC39853.1 xref: EMBL:AAC72843.1 xref: EMBL:AAH00220.1 xref: EMBL:BAA34295.1 xref: EMBL:CAB09986.2 xref: EMBL:CAB09989.2 xref: UniProtKB:O14747 xref: UniProtKB:O15141 xref: UniProtKB:O15208 xref: UniProtKB:Q9BWI3 xref: UniProtKB:Q9UER7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004437 ! DAXX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006000 ! daxx-crebbp-1 physical interaction relationship: participates_in CCO:I0006001 ! crebbp-pax5-1 physical interaction relationship: participates_in CCO:I0006004 ! daxx-dek-1 physical interaction relationship: participates_in CCO:I0006005 ! daxx-hdac-1 physical interaction relationship: participates_in CCO:I0006008 ! daxx-mcrs1-3 physical interaction relationship: participates_in CCO:I0006009 ! mcrs1-daxx-4 physical interaction relationship: participates_in CCO:I0006010 ! daxx-mcrs1-4 physical interaction relationship: participates_in CCO:I0006025 ! daxx-ar-1 physical interaction relationship: participates_in CCO:I0006026 ! daxx-ar-2 physical interaction relationship: participates_in CCO:I0006060 ! daxx-stat3-1 physical interaction relationship: participates_in CCO:I0006061 ! daxx-stat3-2 physical interaction relationship: participates_in CCO:I0006221 ! mdm2-daxx physical interaction relationship: participates_in CCO:I0006222 ! ubp7-daxx physical interaction relationship: participates_in CCO:I0006245 ! dj_1-daxx-2 physical interaction relationship: participates_in CCO:I0006267 ! cenpc1-daxx-1 colocalization relationship: participates_in CCO:I0006269 ! daxx-ubl_1-1 physical interaction relationship: participates_in CCO:I0006270 ! daxx-mcrs1-1 physical interaction relationship: participates_in CCO:I0006272 ! daxx-mcrs1-2 physical interaction relationship: participates_in CCO:I0006273 ! mcrs1-daxx-2 physical interaction relationship: participates_in CCO:I0006274 ! mcrs1-daxx-1 physical interaction relationship: participates_in CCO:I0006275 ! mcrs1-daxx-3 physical interaction relationship: participates_in CCO:I0006276 ! daxx-slc2a4-4 physical interaction relationship: participates_in CCO:I0006277 ! daxx-slc2a4-5 physical interaction relationship: participates_in CCO:I0006349 ! mdm2-daxx-1 physical interaction relationship: participates_in CCO:I0006350 ! ubp7-daxx-2 colocalization relationship: participates_in CCO:I0006351 ! ubp7-daxx-3 direct interaction relationship: participates_in CCO:I0006468 ! daxx-tgfbr2-1 physical interaction relationship: participates_in CCO:I0006469 ! daxx-acvr2-1 physical interaction relationship: participates_in CCO:I0006470 ! daxx-daxx-1 physical interaction relationship: participates_in CCO:I0006519 ! daxx-tsg101 physical interaction relationship: participates_in CCO:I0006520 ! dax-tsg101 physical interaction relationship: participates_in CCO:I0006521 ! dax-tsg101-1 physical interaction relationship: participates_in CCO:I0006522 ! tsg101-daxx physical interaction relationship: participates_in CCO:I0006550 ! tcf4-daxx-2 colocalization relationship: participates_in CCO:I0006559 ! ubp7-daxx-1 physical interaction relationship: participates_in CCO:I0006560 ! ubp7-daxx-5 physical interaction relationship: participates_in CCO:I0006666 ! daxx-stat3 physical interaction relationship: participates_in CCO:I0006680 ! slc2a4-daxx-1 physical interaction relationship: participates_in CCO:I0006681 ! daxx-slc2a4-6 physical interaction relationship: participates_in CCO:I0006710 ! ask1-daxx physical interaction relationship: participates_in CCO:I0006711 ! ask1-daxx-1 physical interaction relationship: participates_in CCO:I0006840 ! tgfbr2-daxx-1 physical interaction relationship: participates_in CCO:I0006846 ! daxx-slc2a4-3 physical interaction relationship: participates_in CCO:I0006902 ! ubp7-daxx-4 physical interaction relationship: participates_in CCO:I0006903 ! daxx-mdm2-1 physical interaction relationship: participates_in CCO:I0006929 ! dj_1-daxx-3 colocalization relationship: participates_in CCO:I0006946 ! daxx-cenpc1-1 physical interaction relationship: participates_in CCO:I0006947 ! daxx-pml-2 colocalization relationship: participates_in CCO:I0006949 ! dek-daxx-1 physical interaction relationship: participates_in CCO:I0007065 ! pml-daxx-1 physical interaction relationship: participates_in CCO:I0007066 ! daxx-pml-1 physical interaction relationship: participates_in CCO:I0007139 ! tcf4-daxx physical interaction relationship: participates_in CCO:I0007140 ! tcf4-daxx-1 physical interaction relationship: participates_in CCO:I0007141 ! daxx-tcf4 physical interaction relationship: participates_in CCO:I0007152 ! daxx-stat3-3 colocalization relationship: participates_in CCO:I0007174 ! dj_1-daxx-1 physical interaction relationship: participates_in CCO:I0007299 ! daxx-mdm2 colocalization relationship: participates_in CCO:I0007370 ! tcf4-daxx-3 physical interaction relationship: participates_in CCO:I0007381 ! ubp7-daxx-6 physical interaction relationship: participates_in CCO:I0007745 ! daxx-ar-4 physical interaction relationship: participates_in CCO:I0007746 ! daxx-ar-5 physical interaction relationship: participates_in CCO:I0007783 ! dapk3-daxx-3 physical interaction relationship: participates_in CCO:I0007808 ! ubp7-daxx-7 physical interaction relationship: participates_in CCO:I0007809 ! ubp7-daxx-8 physical interaction relationship: participates_in CCO:I0007810 ! ubp7-daxx-9 physical interaction relationship: participates_in CCO:I0007811 ! mdm2-daxx-2 physical interaction relationship: participates_in CCO:I0007812 ! usp7-hausp physical interaction relationship: participates_in CCO:I0007842 ! daxx-slc2a4-1 physical interaction relationship: participates_in CCO:I0007843 ! daxx-slc2a4-2 physical interaction relationship: participates_in CCO:I0007868 ! daxx-ar-3 physical interaction relationship: participates_in CCO:I0007928 ! daxx-usp7 physical interaction relationship: participates_in CCO:I0007971 ! ubp7-daxx-10 physical interaction relationship: participates_in CCO:P0000040 ! cytokinesis after mitosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011428 ! DAXX_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0011429 ! DAXX_HUMAN-Phosphothreonine459 relationship: transforms_into CCO:B0011430 ! DAXX_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0011431 ! DAXX_HUMAN-Phosphotyrosine648 relationship: transforms_into CCO:B0011432 ! DAXX_HUMAN-Phosphoserine668 relationship: transforms_into CCO:B0011433 ! DAXX_HUMAN-Phosphoserine671 relationship: transforms_into CCO:B0011434 ! DAXX_HUMAN-Phosphothreonine709 relationship: transforms_into CCO:B0011435 ! DAXX_HUMAN-Phosphoserine712 relationship: transforms_into CCO:B0011436 ! DAXX_HUMAN-Phosphoserine737 relationship: transforms_into CCO:B0011437 ! DAXX_HUMAN-Phosphoserine739 relationship: transforms_into CCO:B0048217 ! DAXX_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0048218 ! DAXX_HUMAN-Phosphoserine688 relationship: transforms_into CCO:B0048219 ! DAXX_HUMAN-Phosphoserine690 relationship: transforms_into CCO:B0048220 ! DAXX_HUMAN-Phosphoserine702 [Term] id: CCO:B0002197 name: DMBT1_HUMAN def: "Deleted in malignant brain tumors 1 protein precursor" [UniProtKB:Q9UGM3] synonym: "Glycoprotein 340" EXACT [UniProtKB:Q9UGM3] synonym: "Gp-340" EXACT [UniProtKB:Q9UGM3] synonym: "Hensin" EXACT [UniProtKB:Q9UGM3] synonym: "Surfactant pulmonary-associated D-binding protein" EXACT [UniProtKB:Q9UGM3] xref: EMBL:AAD49696.1 xref: EMBL:AAI53300.1 xref: EMBL:BAA78577.1 xref: EMBL:BAD92928.1 xref: EMBL:CAA04019.1 xref: EMBL:CAB56155.1 xref: EMBL:CAB63941.1 xref: EMBL:CAB63942.1 xref: EMBL:CAC44122.1 xref: EMBL:CAE45995.1 xref: EMBL:CAI14487.1 xref: EMBL:CAI14488.1 xref: EMBL:CAI14489.1 xref: EMBL:CAI14490.1 xref: EMBL:CAI14491.1 xref: EMBL:CAI14492.1 xref: EMBL:CAI14493.1 xref: EMBL:CAI14494.1 xref: EMBL:CAI14495.1 xref: EMBL:CAI14496.1 xref: UniProtKB:A6NDJ5 xref: UniProtKB:A8E4R5 xref: UniProtKB:B1ARE7 xref: UniProtKB:B1ARE8 xref: UniProtKB:B1ARE9 xref: UniProtKB:B1ARF0 xref: UniProtKB:Q59EX0 xref: UniProtKB:Q5JR26 xref: UniProtKB:Q6MZN4 xref: UniProtKB:Q96DU4 xref: UniProtKB:Q9UGM2 xref: UniProtKB:Q9UGM3 xref: UniProtKB:Q9UJ57 xref: UniProtKB:Q9UKJ4 xref: UniProtKB:Q9Y211 xref: UniProtKB:Q9Y4V9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004484 ! DMBT1_human relationship: has_function CCO:F0001365 ! scavenger receptor activity relationship: has_function CCO:F0001838 ! pattern recognition receptor activity relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001034 ! phagocytic vesicle membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0002198 name: SEPT3_HUMAN def: "Neuronal-specific septin-3" [UniProtKB:Q9UH03] xref: EMBL:AAG00517.1 xref: EMBL:AAG00518.1 xref: EMBL:AAG00519.1 xref: EMBL:AAI11780.2 xref: EMBL:BAD92389.1 xref: EMBL:CAD38797.1 xref: EMBL:CAG30458.1 xref: EMBL:CAI41693.1 xref: UniProtKB:Q2NKJ7 xref: UniProtKB:Q59GF7 xref: UniProtKB:Q6IBZ6 xref: UniProtKB:Q8N3P3 xref: UniProtKB:Q9HD35 xref: UniProtKB:Q9UH03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005586 ! SEPT3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001135 ! septin complex relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0008505 ! sept3-wbp2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013994 ! SEPT3_HUMAN-Phosphoserine91 [Term] id: CCO:B0002199 name: UN84B_HUMAN def: "Protein unc-84 homolog B" [UniProtKB:Q9UH99] synonym: "Rab5-interacting protein" EXACT [UniProtKB:Q9UH99] synonym: "Rab5IP" EXACT [UniProtKB:Q9UH99] synonym: "Sad1/unc-84 protein-like 2" EXACT [UniProtKB:Q9UH99] xref: EMBL:AAF15887.1 xref: EMBL:AAH30684.2 xref: EMBL:AAI11718.1 xref: EMBL:AAT90500.1 xref: EMBL:BAA31643.1 xref: EMBL:CAD97926.1 xref: EMBL:CAG30360.1 xref: EMBL:CAI21604.1 xref: UniProtKB:O75156 xref: UniProtKB:Q2NKN8 xref: UniProtKB:Q6B4H1 xref: UniProtKB:Q7Z3E3 xref: UniProtKB:Q9UH99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005884 ! UNC84B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: transforms_into CCO:B0014581 ! UN84B_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0014583 ! UN84B_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0014584 ! UN84B_HUMAN-Phosphoserine116 [Term] id: CCO:B0002200 name: MLH3_HUMAN def: "DNA mismatch repair protein Mlh3" [UniProtKB:Q9UHC1] synonym: "MutL protein homolog 3" EXACT [UniProtKB:Q9UHC1] xref: EMBL:AAC42005.1 xref: EMBL:AAF23904.1 xref: EMBL:AAF23905.1 xref: EMBL:AAX59030.1 xref: EMBL:BAA92353.1 xref: UniProtKB:P49751 xref: UniProtKB:Q56DK9 xref: UniProtKB:Q9P292 xref: UniProtKB:Q9UHC0 xref: UniProtKB:Q9UHC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005101 ! MLH3_human relationship: has_function CCO:F0000287 ! satellite DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000122 ! meiotic recombination relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0036014 ! MLH3_HUMAN-Phosphothreonine606 relationship: transforms_into CCO:B0036015 ! MLH3_HUMAN-Phosphothreonine610 [Term] id: CCO:B0002201 name: SEPT9_HUMAN def: "Septin-9" [UniProtKB:Q9UHD8] synonym: "MLL septin-like fusion protein" EXACT [UniProtKB:Q9UHD8] synonym: "MLL septin-like fusion protein MSF-A" EXACT [UniProtKB:Q9UHD8] synonym: "Ov/Br septin" EXACT [UniProtKB:Q9UHD8] synonym: "Ovarian/Breast septin" EXACT [UniProtKB:Q9UHD8] synonym: "Septin D1" EXACT [UniProtKB:Q9UHD8] xref: EMBL:AAD39749.1 xref: EMBL:AAF23373.1 xref: EMBL:AAF23374.1 xref: EMBL:AAG27919.1 xref: EMBL:AAH21192.1 xref: EMBL:AAH54004.1 xref: EMBL:AAP35879.1 xref: EMBL:BAA76835.2 xref: EMBL:BAB14057.1 xref: EMBL:CAB45728.1 xref: EMBL:CAC42221.1 xref: EMBL:CAC42222.1 xref: EMBL:CAC42223.1 xref: EMBL:CAC42224.1 xref: UniProtKB:Q96QF3 xref: UniProtKB:Q96QF4 xref: UniProtKB:Q96QF5 xref: UniProtKB:Q9HA04 xref: UniProtKB:Q9UG40 xref: UniProtKB:Q9UHD8 xref: UniProtKB:Q9Y5W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005592 ! SEPT9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014010 ! SEPT9_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0014011 ! SEPT9_HUMAN-Phosphothreonine42 relationship: transforms_into CCO:B0014012 ! SEPT9_HUMAN-Phosphothreonine49 relationship: transforms_into CCO:B0014013 ! SEPT9_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0014014 ! SEPT9_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0014015 ! SEPT9_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0014016 ! SEPT9_HUMAN-Phosphothreonine142 relationship: transforms_into CCO:B0070374 ! SEPT9_HUMAN-Phosphothreonine38 relationship: transforms_into CCO:B0070375 ! SEPT9_HUMAN-Phosphotyrosine278 [Term] id: CCO:B0002202 name: SRTD1_HUMAN def: "SERTA domain-containing protein 1" [UniProtKB:Q9UHV2] synonym: "CDK4-binding protein p34SEI1" EXACT [UniProtKB:Q9UHV2] synonym: "SEI-1" EXACT [UniProtKB:Q9UHV2] synonym: "Transcriptional regulator interacting with the PHD-bromodomain 1" EXACT [UniProtKB:Q9UHV2] synonym: "TRIP-Br1" EXACT [UniProtKB:Q9UHV2] xref: EMBL:AAF08349.1 xref: EMBL:AAH02670.1 xref: EMBL:AAK52831.1 xref: EMBL:AAM77800.1 xref: UniProtKB:Q9BUE7 xref: UniProtKB:Q9UHV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005673 ! SERTAD1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007627 ! atxn7l3-sertad1 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0002204 name: MD2L2_HUMAN def: "Mitotic spindle assembly checkpoint protein MAD2B" [UniProtKB:Q9UI95] synonym: "hREV7" EXACT [UniProtKB:Q9UI95] synonym: "MAD2-like 2" EXACT [UniProtKB:Q9UI95] xref: EMBL:AAD30290.1 xref: EMBL:AAD41647.1 xref: EMBL:AAF20267.1 xref: EMBL:AAF34357.1 xref: EMBL:AAH15244.1 xref: EMBL:AAY26393.1 xref: EMBL:CAI20218.1 xref: UniProtKB:Q5TGW7 xref: UniProtKB:Q9UI95 xref: UniProtKB:Q9UNA7 xref: UniProtKB:Q9Y6I6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005049 ! MAD2L2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006043 ! adam9-mad2l2-3 physical interaction relationship: participates_in CCO:I0006628 ! adam9-mad2l2-2 physical interaction relationship: participates_in CCO:I0007286 ! adam9-mad2l2-1 physical interaction relationship: participates_in CCO:I0007337 ! bat2-mad2l2 physical interaction relationship: participates_in CCO:I0007391 ! adam15-mad2l2-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000105 ! mitotic cell cycle spindle assembly checkpoint relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002205 name: MUTYH_HUMAN def: "A/G-specific adenine DNA glycosylase" [UniProtKB:Q9UIF7] synonym: "EC 3.2.2.-" EXACT [UniProtKB:Q9UIF7] synonym: "hMYH" EXACT [UniProtKB:Q9UIF7] synonym: "MutY homolog" EXACT [UniProtKB:Q9UIF7] xref: EMBL:AAC50618.1 xref: EMBL:AAH03178.1 xref: EMBL:AAM78555.1 xref: EMBL:BAA89336.1 xref: EMBL:BAA89337.1 xref: EMBL:BAA89338.1 xref: EMBL:BAA89339.1 xref: EMBL:BAA89340.1 xref: EMBL:BAA89341.1 xref: EMBL:BAA89342.1 xref: EMBL:BAA89343.1 xref: EMBL:BAA89344.1 xref: EMBL:BAA89345.1 xref: EMBL:CAI21713.1 xref: EMBL:CAI21714.1 xref: EMBL:CAI21718.1 xref: EMBL:CAI21719.1 xref: EMBL:CAI21720.1 xref: UniProtKB:Q15830 xref: UniProtKB:Q9UBP2 xref: UniProtKB:Q9UBS7 xref: UniProtKB:Q9UIF4 xref: UniProtKB:Q9UIF5 xref: UniProtKB:Q9UIF6 xref: UniProtKB:Q9UIF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005138 ! MUTYH_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0004051 ! DNA N-glycosylase activity relationship: has_function CCO:F0004985 ! MutLalpha complex binding relationship: has_function CCO:F0004986 ! MutLbeta complex binding relationship: has_function CCO:F0004987 ! MutSalpha complex binding relationship: has_function CCO:F0004988 ! MutSbeta complex binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008141 ! 4 iron, 4 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0008483 ! lrsam1-mutyh physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0002206 name: HERC5_HUMAN def: "Probable E3 ubiquitin-protein ligase HERC5" [UniProtKB:Q9UII4] synonym: "Cyclin-E-binding protein 1" EXACT [UniProtKB:Q9UII4] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9UII4] synonym: "HECT domain and RCC1-like domain-containing protein 5" EXACT [UniProtKB:Q9UII4] xref: EMBL:BAA88519.1 xref: UniProtKB:Q9UII4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004800 ! HERC5_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity [Term] id: CCO:B0002207 name: DUS13_HUMAN def: "Dual specificity protein phosphatase 13" [UniProtKB:Q9UII6] synonym: "Dual specificity phosphatase SKRP4" EXACT [UniProtKB:Q9UII6] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9UII6] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9UII6] synonym: "Testis- and skeletal-muscle-specific DSP" EXACT [UniProtKB:Q9UII6] xref: EMBL:AAH09778.1 xref: EMBL:BAA89412.1 xref: EMBL:BAD91014.1 xref: EMBL:CAI40905.1 xref: UniProtKB:Q5JSC6 xref: UniProtKB:Q96GC2 xref: UniProtKB:Q9UII6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004520 ! DUSP13_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0002208 name: KIF25_HUMAN def: "Kinesin-like protein KIF25" [UniProtKB:Q9UIL4] synonym: "Kinesin-like protein 3" EXACT [UniProtKB:Q9UIL4] xref: EMBL:BAA36417.1 xref: EMBL:BAA36418.1 xref: EMBL:CAI12327.1 xref: UniProtKB:O94775 xref: UniProtKB:Q5SZU9 xref: UniProtKB:Q9UIL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004945 ! KIF25_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:B0002209 name: STAG3_HUMAN def: "Cohesin subunit SA-3" [UniProtKB:Q9UJ98] synonym: "SCC3 homolog 3" EXACT [UniProtKB:Q9UJ98] synonym: "Stromal antigen 3" EXACT [UniProtKB:Q9UJ98] synonym: "Stromalin 3" EXACT [UniProtKB:Q9UJ98] xref: EMBL:CAB59367.1 xref: EMBL:CAD38679.2 xref: UniProtKB:Q8NDP3 xref: UniProtKB:Q9UJ98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005685 ! STAG3_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000122 ! synaptonemal complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000121 ! synaptonemal complex assembly relationship: participates_in CCO:P0000695 ! chromosome segregation [Term] id: CCO:B0002210 name: MCM8_HUMAN def: "DNA replication licensing factor MCM8" [UniProtKB:Q9UJA3] synonym: "Minichromosome maintenance 8" EXACT [UniProtKB:Q9UJA3] xref: EMBL:AAH08830.2 xref: EMBL:AAH80656.1 xref: EMBL:AAI01055.1 xref: EMBL:AAI01057.1 xref: EMBL:AAI01058.1 xref: EMBL:AAO21222.1 xref: EMBL:BAB55260.1 xref: EMBL:CAB55276.2 xref: EMBL:CAD27750.1 xref: EMBL:CAI23480.1 xref: UniProtKB:Q495R4 xref: UniProtKB:Q495R7 xref: UniProtKB:Q86US4 xref: UniProtKB:Q969I5 xref: UniProtKB:Q9UJA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005043 ! MCM8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0002211 name: TBE_HUMAN def: "Tubulin epsilon chain" [UniProtKB:Q9UJT0] synonym: "Epsilon-tubulin" EXACT [UniProtKB:Q9UJT0] xref: EMBL:AAF09585.1 xref: EMBL:AAH25405.1 xref: EMBL:AAH31101.1 xref: UniProtKB:Q8NEG3 xref: UniProtKB:Q9UJT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005739 ! TUBE1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000043 ! pericentriolar material relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:P0000108 ! centrosome cycle [Term] id: CCO:B0002212 name: CDC23_HUMAN def: "Cell division cycle protein 23 homolog" [UniProtKB:Q9UJX2] synonym: "Anaphase-promoting complex subunit 8" EXACT [UniProtKB:Q9UJX2] synonym: "APC8" EXACT [UniProtKB:Q9UJX2] synonym: "Cyclosome subunit 8" EXACT [UniProtKB:Q9UJX2] xref: EMBL:AAC70920.1 xref: EMBL:AAF05755.1 xref: EMBL:AAH05258.1 xref: EMBL:AAH10944.1 xref: EMBL:AAH17713.1 xref: EMBL:AAP88812.1 xref: EMBL:AAS99353.1 xref: EMBL:BAA75628.1 xref: UniProtKB:O75433 xref: UniProtKB:Q9BS73 xref: UniProtKB:Q9UJX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004285 ! CDC23_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005801 ! cdc23-rad54b physical interaction relationship: participates_in CCO:I0005806 ! cdc23-rbpms physical interaction relationship: participates_in CCO:I0005848 ! cdc23-tsc22d4 physical interaction relationship: participates_in CCO:I0007929 ! cdc27-nek2 physical interaction relationship: participates_in CCO:P0000011 ! G1 phase of mitotic cell cycle relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000094 ! mitotic metaphase plate congression relationship: participates_in CCO:P0000102 ! mitotic metaphase/anaphase transition relationship: participates_in CCO:P0000107 ! regulation of exit from mitosis relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011060 ! CDC23_HUMAN-Phosphotyrosine267 relationship: transforms_into CCO:B0011061 ! CDC23_HUMAN-Phosphothreonine556 relationship: transforms_into CCO:B0011062 ! CDC23_HUMAN-Phosphothreonine559 relationship: transforms_into CCO:B0011063 ! CDC23_HUMAN-Phosphoserine572 relationship: transforms_into CCO:B0011064 ! CDC23_HUMAN-Phosphoserine582 relationship: transforms_into CCO:B0011065 ! CDC23_HUMAN-Phosphothreonine590 relationship: transforms_into CCO:B0064187 ! CDC23_HUMAN-Phosphothreonine578 relationship: transforms_into CCO:B0064188 ! CDC23_HUMAN-Phosphoserine587 [Term] id: CCO:B0002213 name: APC7_HUMAN def: "Anaphase-promoting complex subunit 7" [UniProtKB:Q9UJX3] synonym: "APC7" EXACT [UniProtKB:Q9UJX3] synonym: "Cyclosome subunit 7" EXACT [UniProtKB:Q9UJX3] xref: EMBL:AAF05754.1 xref: EMBL:AAH02941.2 xref: EMBL:AAH09498.2 xref: EMBL:AAH17316.2 xref: EMBL:CAB70828.1 xref: UniProtKB:Q96AC4 xref: UniProtKB:Q96GF4 xref: UniProtKB:Q9BU24 xref: UniProtKB:Q9NT16 xref: UniProtKB:Q9UJX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004080 ! ANAPC7_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002214 name: APC5_HUMAN def: "Anaphase-promoting complex subunit 5" [UniProtKB:Q9UJX4] synonym: "APC5" EXACT [UniProtKB:Q9UJX4] synonym: "Cyclosome subunit 5" EXACT [UniProtKB:Q9UJX4] xref: EMBL:AAF05753.1 xref: EMBL:AAH01081.1 xref: EMBL:AAH01950.1 xref: EMBL:AAH06301.1 xref: EMBL:AAH34243.1 xref: EMBL:CAD97812.1 xref: UniProtKB:Q8N4H7 xref: UniProtKB:Q9BQD4 xref: UniProtKB:Q9UJX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004057 ! ANAPC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000020 ! mitotic anaphase relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041124 ! APC5_HUMAN-Phosphoserine195 relationship: transforms_into CCO:B0041125 ! APC5_HUMAN-Phosphoserine217 [Term] id: CCO:B0002215 name: APC4_HUMAN def: "Anaphase-promoting complex subunit 4" [UniProtKB:Q9UJX5] synonym: "APC4" EXACT [UniProtKB:Q9UJX5] synonym: "Cyclosome subunit 4" EXACT [UniProtKB:Q9UJX5] xref: EMBL:AAF05752.1 xref: EMBL:AAH59383.1 xref: EMBL:BAF85025.1 xref: EMBL:CAB89245.1 xref: EMBL:EAW92839.1 xref: UniProtKB:A8K8H1 xref: UniProtKB:Q6PCC6 xref: UniProtKB:Q9NSH6 xref: UniProtKB:Q9UJX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004056 ! ANAPC4_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000020 ! mitotic anaphase relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041122 ! APC4_HUMAN-Phosphotyrosine469 relationship: transforms_into CCO:B0041123 ! APC4_HUMAN-Phosphoserine779 relationship: transforms_into CCO:B0065688 ! APC4_HUMAN-Phosphoserine777 [Term] id: CCO:B0002216 name: ANC2_HUMAN def: "Anaphase-promoting complex subunit 2" [UniProtKB:Q9UJX6] synonym: "APC2" EXACT [UniProtKB:Q9UJX6] synonym: "Cyclosome subunit 2" EXACT [UniProtKB:Q9UJX6] xref: EMBL:AAF05751.1 xref: EMBL:AAH01579.1 xref: EMBL:AAH09487.2 xref: EMBL:AAH32503.1 xref: EMBL:BAA92644.1 xref: EMBL:CAH72881.1 xref: UniProtKB:Q5VSG1 xref: UniProtKB:Q96DG5 xref: UniProtKB:Q96GG4 xref: UniProtKB:Q9P2E1 xref: UniProtKB:Q9UJX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004055 ! ANAPC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007929 ! cdc27-nek2 physical interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000141 ! cyclin catabolic process relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010521 ! ANC2_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0010522 ! ANC2_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0010523 ! ANC2_HUMAN-Phosphoserine534 relationship: transforms_into CCO:B0031290 ! ANC2_HUMAN-Phosphotyrosine810 relationship: transforms_into CCO:B0065624 ! ANC2_HUMAN-Phosphoserine470 [Term] id: CCO:B0002217 name: ING1_HUMAN def: "Inhibitor of growth protein 1" [UniProtKB:Q9UK53] xref: EMBL:AAB60879.1 xref: EMBL:AAC00501.1 xref: EMBL:AAF07920.1 xref: EMBL:AAF07921.1 xref: EMBL:AAF37421.1 xref: EMBL:AAF37422.1 xref: EMBL:AAF37423.1 xref: EMBL:AAG02578.1 xref: EMBL:AAG02579.1 xref: EMBL:AAG12174.1 xref: EMBL:AAG12175.1 xref: EMBL:BAA82886.1 xref: EMBL:BAA82887.1 xref: EMBL:BAA82888.1 xref: EMBL:BAA82889.1 xref: EMBL:BAA82890.1 xref: EMBL:BAA83462.1 xref: EMBL:BAA83496.1 xref: EMBL:BAB08101.1 xref: EMBL:BAB08102.1 xref: EMBL:BAB08103.1 xref: EMBL:BAB20992.2 xref: EMBL:CAC38067.1 xref: EMBL:CAI16974.1 xref: UniProtKB:O00532 xref: UniProtKB:O43658 xref: UniProtKB:Q5T9G9 xref: UniProtKB:Q9H007 xref: UniProtKB:Q9HD98 xref: UniProtKB:Q9HD99 xref: UniProtKB:Q9NS83 xref: UniProtKB:Q9P0U6 xref: UniProtKB:Q9UBC6 xref: UniProtKB:Q9UIJ1 xref: UniProtKB:Q9UIJ2 xref: UniProtKB:Q9UIJ3 xref: UniProtKB:Q9UIJ4 xref: UniProtKB:Q9UK52 xref: UniProtKB:Q9UK53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004892 ! ING1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0002218 name: CCNL1_HUMAN def: "Cyclin-L1" [UniProtKB:Q9UK58] synonym: "Cyclin-L" EXACT [UniProtKB:Q9UK58] xref: EMBL:AAD53184.1 xref: EMBL:AAF64257.1 xref: EMBL:AAH07081.1 xref: EMBL:AAH38394.1 xref: EMBL:AAH67812.1 xref: EMBL:AAK61551.1 xref: EMBL:AAM21204.1 xref: EMBL:AAM21205.1 xref: EMBL:AAQ89026.1 xref: UniProtKB:Q6NVY9 xref: UniProtKB:Q6UWS7 xref: UniProtKB:Q8NI48 xref: UniProtKB:Q96QT0 xref: UniProtKB:Q9NZF3 xref: UniProtKB:Q9UK58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004261 ! CCNL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011004 ! CCNL1_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0011005 ! CCNL1_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0043225 ! CCNL1_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0064117 ! CCNL1_HUMAN-Phosphothreonine325 relationship: transforms_into CCO:B0064118 ! CCNL1_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0064119 ! CCNL1_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0064120 ! CCNL1_HUMAN-Phosphoserine342 [Term] id: CCO:B0002219 name: DP13A_HUMAN def: "DCC-interacting protein 13-alpha" [UniProtKB:Q9UKG1] synonym: "Adapter protein containing PH domain, PTB domain and leucine zipper motif 1" EXACT [UniProtKB:Q9UKG1] synonym: "Dip13-alpha" EXACT [UniProtKB:Q9UKG1] xref: EMBL:AAF04012.1 xref: EMBL:AAH28599.1 xref: EMBL:AAL17835.1 xref: EMBL:BAA92666.2 xref: UniProtKB:Q9P2B9 xref: UniProtKB:Q9UKG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004497 ! APPL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005733 ! appl1-dip13b physical interaction relationship: participates_in CCO:I0005812 ! appl1-traf2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011566 ! DP13A_HUMAN-Phosphoserine401 relationship: transforms_into CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: transforms_into CCO:B0064850 ! DP13A_HUMAN-Phosphothreonine399 [Term] id: CCO:B0002220 name: TLK1_HUMAN def: "Serine/threonine-protein kinase tousled-like 1" [UniProtKB:Q9UKI8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UKI8] synonym: "PKU-beta" EXACT [UniProtKB:Q9UKI8] synonym: "Tousled-like kinase 1" EXACT [UniProtKB:Q9UKI8] xref: EMBL:AAF03094.1 xref: EMBL:AAF71263.1 xref: EMBL:AAH32657.1 xref: EMBL:BAA09486.2 xref: EMBL:BAA20562.1 xref: UniProtKB:Q14150 xref: UniProtKB:Q8N591 xref: UniProtKB:Q9NYH2 xref: UniProtKB:Q9UKI8 xref: UniProtKB:Q9Y4F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005791 ! TLK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005725 ! tlk1-tlk1 physical interaction relationship: participates_in CCO:I0005855 ! dkfzp564e2182-tlk1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000469 ! regulation of chromatin assembly or disassembly relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0014409 ! TLK1_HUMAN-Phosphoserine159 relationship: transforms_into CCO:B0014410 ! TLK1_HUMAN-Phosphothreonine179 relationship: transforms_into CCO:B0014411 ! TLK1_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0014412 ! TLK1_HUMAN-Phosphoserine743 [Term] id: CCO:B0002221 name: FBX5_HUMAN def: "F-box only protein 5" [UniProtKB:Q9UKT4] synonym: "Early mitotic inhibitor 1" EXACT [UniProtKB:Q9UKT4] xref: EMBL:AAF04469.1 xref: EMBL:AAH18905.1 xref: EMBL:AAL86610.1 xref: EMBL:CAI18895.1 xref: UniProtKB:Q8WV29 xref: UniProtKB:Q9UGC8 xref: UniProtKB:Q9UKT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004626 ! FBXO5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006995 ! fbxo5-plk1 phosphorylation relationship: participates_in CCO:I0006996 ! fbxo5-plk1-1 phosphorylation relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000138 ! regulation of mitotic cell cycle relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002222 name: HDAC9_HUMAN def: "Histone deacetylase 9" [UniProtKB:Q9UKV0] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q9UKV0] synonym: "HD7" EXACT [UniProtKB:Q9UKV0] synonym: "HD7B" EXACT [UniProtKB:Q9UKV0] synonym: "HD9" EXACT [UniProtKB:Q9UKV0] synonym: "Histone deacetylase-related protein" EXACT [UniProtKB:Q9UKV0] synonym: "MEF2-interacting transcription repressor MITR" EXACT [UniProtKB:Q9UKV0] xref: EMBL:AAC78618.2 xref: EMBL:AAF04254.1 xref: EMBL:AAI11736.1 xref: EMBL:AAK66821.1 xref: EMBL:AAK66822.1 xref: EMBL:AAO27363.1 xref: EMBL:BAA34464.2 xref: EMBL:CAD30851.1 xref: UniProtKB:O94845 xref: UniProtKB:O95028 xref: UniProtKB:Q2M2R6 xref: UniProtKB:Q86SL1 xref: UniProtKB:Q86US3 xref: UniProtKB:Q9UKV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004793 ! HDAC9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012172 ! HDAC9_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0012173 ! HDAC9_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0012174 ! HDAC9_HUMAN-Phosphoserine451 [Term] id: CCO:B0002223 name: MCTS1_HUMAN def: "Malignant T cell amplified sequence 1" [UniProtKB:Q9ULC4] synonym: "MCT-1" EXACT [UniProtKB:Q9ULC4] synonym: "Multiple copies T-cell malignancies" EXACT [UniProtKB:Q9ULC4] xref: EMBL:AAH01013.1 xref: EMBL:AAH95461.1 xref: EMBL:AAQ76817.1 xref: EMBL:BAA86055.1 xref: EMBL:BAG34931.1 xref: EMBL:EAX11874.1 xref: UniProtKB:Q502X6 xref: UniProtKB:Q9ULC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006056 ! MCTS1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0068071 ! MCTS1_HUMAN-Phosphothreonine81 relationship: transforms_into CCO:B0068072 ! MCTS1_HUMAN-Phosphoserine118 [Term] id: CCO:B0002224 name: MTUS1_HUMAN def: "Mitochondrial tumor suppressor 1" [UniProtKB:Q9ULD2] synonym: "Angiotensin-II type 2 receptor-interacting protein" EXACT [UniProtKB:Q9ULD2] xref: EMBL:AAG33674.1 xref: EMBL:AAH07328.1 xref: EMBL:AAH33842.1 xref: EMBL:AAI42972.1 xref: EMBL:AAL37035.1 xref: EMBL:AAQ24172.1 xref: EMBL:BAA86602.1 xref: EMBL:BAB14894.1 xref: EMBL:CAB50791.1 xref: EMBL:CAH56128.1 xref: UniProtKB:Q63HJ6 xref: UniProtKB:Q659F4 xref: UniProtKB:Q6PK49 xref: UniProtKB:Q6URW7 xref: UniProtKB:Q8N4M6 xref: UniProtKB:Q8WTT9 xref: UniProtKB:Q9H7T2 xref: UniProtKB:Q9ULD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005137 ! MTUS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0013041 ! MTUS1_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0013042 ! MTUS1_HUMAN-Phosphoserine443 relationship: transforms_into CCO:B0013043 ! MTUS1_HUMAN-Phosphoserine620 relationship: transforms_into CCO:B0013044 ! MTUS1_HUMAN-Phosphoserine1245 relationship: transforms_into CCO:B0013045 ! MTUS1_HUMAN-Phosphoserine1255 relationship: transforms_into CCO:B0013046 ! MTUS1_HUMAN-Phosphoserine1264 relationship: transforms_into CCO:B0013047 ! MTUS1_HUMAN-Phosphoserine1266 relationship: transforms_into CCO:B0013048 ! MTUS1_HUMAN-Phosphoserine1268 [Term] id: CCO:B0002225 name: CCPG1_HUMAN def: "Cell cycle progression protein 1" [UniProtKB:Q9ULG6] synonym: "Cell cycle progression restoration protein 8" EXACT [UniProtKB:Q9ULG6] xref: EMBL:AAB69314.1 xref: EMBL:AAH15203.1 xref: EMBL:AAH29398.1 xref: EMBL:AAH34914.1 xref: EMBL:AAH39871.1 xref: EMBL:AAK14914.1 xref: EMBL:BAA86568.2 xref: EMBL:BAB14042.1 xref: EMBL:EAW77481.1 xref: UniProtKB:A0PJH3 xref: UniProtKB:O14712 xref: UniProtKB:Q05DG4 xref: UniProtKB:Q5U5S7 xref: UniProtKB:Q8IYV8 xref: UniProtKB:Q9BY53 xref: UniProtKB:Q9HA17 xref: UniProtKB:Q9ULG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004265 ! CCPG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0011011 ! CCPG1_HUMAN-Phosphothreonine99 relationship: transforms_into CCO:B0011012 ! CCPG1_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0011013 ! CCPG1_HUMAN-Phosphoserine104 [Term] id: CCO:B0002227 name: TPX2_HUMAN def: "Targeting protein for Xklp2" [UniProtKB:Q9ULW0] synonym: "Differentially expressed in cancerous and non-cancerous lung cells 2" EXACT [UniProtKB:Q9ULW0] synonym: "DIL-2" EXACT [UniProtKB:Q9ULW0] synonym: "Hepatocellular carcinoma-associated antigen 519" EXACT [UniProtKB:Q9ULW0] synonym: "p100" EXACT [UniProtKB:Q9ULW0] synonym: "Protein fls353" EXACT [UniProtKB:Q9ULW0] synonym: "Restricted expression proliferation-associated protein 100" EXACT [UniProtKB:Q9ULW0] xref: EMBL:AAD33965.1 xref: EMBL:AAF03248.1 xref: EMBL:AAF81695.1 xref: EMBL:AAH04136.1 xref: EMBL:AAH20207.1 xref: EMBL:BAA76931.1 xref: EMBL:BAA85893.1 xref: EMBL:CAB55982.1 xref: EMBL:CAD38007.1 xref: UniProtKB:Q9H1R4 xref: UniProtKB:Q9NRA3 xref: UniProtKB:Q9UFN9 xref: UniProtKB:Q9UL00 xref: UniProtKB:Q9ULW0 xref: UniProtKB:Q9Y2M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005819 ! TPX2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007021 ! stk6-tpx2-1 direct interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0014513 ! TPX2_HUMAN-Phosphothreonine51 relationship: transforms_into CCO:B0014514 ! TPX2_HUMAN-Phosphothreonine72 relationship: transforms_into CCO:B0014515 ! TPX2_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0014516 ! TPX2_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0014517 ! TPX2_HUMAN-Phosphothreonine147 relationship: transforms_into CCO:B0014518 ! TPX2_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0014519 ! TPX2_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0014520 ! TPX2_HUMAN-Phosphothreonine338 relationship: transforms_into CCO:B0014521 ! TPX2_HUMAN-Phosphoserine359 relationship: transforms_into CCO:B0014522 ! TPX2_HUMAN-Phosphothreonine369 relationship: transforms_into CCO:B0014523 ! TPX2_HUMAN-Phosphothreonine374 relationship: transforms_into CCO:B0014524 ! TPX2_HUMAN-Phosphoserine486 relationship: transforms_into CCO:B0014525 ! TPX2_HUMAN-Phosphoserine542 relationship: transforms_into CCO:B0014526 ! TPX2_HUMAN-Phosphoserine634 relationship: transforms_into CCO:B0014527 ! TPX2_HUMAN-Phosphoserine652 relationship: transforms_into CCO:B0014528 ! TPX2_HUMAN-Phosphoserine654 relationship: transforms_into CCO:B0014529 ! TPX2_HUMAN-Phosphoserine738 relationship: transforms_into CCO:B0071487 ! TPX2_HUMAN-Phosphothreonine59 relationship: transforms_into CCO:B0071488 ! TPX2_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0071489 ! TPX2_HUMAN-Phosphoserine310 [Term] id: CCO:B0002228 name: ASC_HUMAN def: "Apoptosis-associated speck-like protein containing a CARD" [UniProtKB:Q9ULZ3] synonym: "Caspase recruitment domain-containing protein 5" EXACT [UniProtKB:Q9ULZ3] synonym: "hASC" EXACT [UniProtKB:Q9ULZ3] synonym: "PYD and CARD domain-containing protein" EXACT [UniProtKB:Q9ULZ3] synonym: "Target of methylation-induced silencing 1" EXACT [UniProtKB:Q9ULZ3] xref: EMBL:AAF99665.1 xref: EMBL:AAG01187.1 xref: EMBL:AAG01188.1 xref: EMBL:AAG30286.1 xref: EMBL:AAH04470.1 xref: EMBL:AAH13569.2 xref: EMBL:AAK63850.1 xref: EMBL:BAA87339.2 xref: EMBL:BAA91012.1 xref: UniProtKB:Q96D12 xref: UniProtKB:Q9BSZ5 xref: UniProtKB:Q9HBD0 xref: UniProtKB:Q9NXJ8 xref: UniProtKB:Q9ULZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004105 ! PYCARD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_function CCO:F0004944 ! Pyrin domain binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000547 ! IkappaB kinase complex relationship: participates_in CCO:I0005908 ! prkar1a-pycard physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001810 ! tumor necrosis factor-mediated signaling pathway relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002178 ! positive regulation of caspase activity relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0002229 name: FZR_HUMAN def: "Fizzy-related protein homolog" [UniProtKB:Q9UM11] synonym: "CDC20-like protein 1" EXACT [UniProtKB:Q9UM11] synonym: "Cdh1/Hct1 homolog" EXACT [UniProtKB:Q9UM11] synonym: "Fzr" EXACT [UniProtKB:Q9UM11] synonym: "hCDH1" EXACT [UniProtKB:Q9UM11] xref: EMBL:AAC62835.1 xref: EMBL:AAC62836.1 xref: EMBL:AAD26623.1 xref: EMBL:AAD26624.1 xref: EMBL:AAD52030.1 xref: EMBL:AAF20266.1 xref: EMBL:AAH13413.1 xref: EMBL:AAL28117.1 xref: EMBL:AAP35779.1 xref: EMBL:BAA86556.1 xref: EMBL:BAA86954.1 xref: EMBL:BAA86955.1 xref: UniProtKB:O75869 xref: UniProtKB:Q86U66 xref: UniProtKB:Q96NW8 xref: UniProtKB:Q9UI96 xref: UniProtKB:Q9ULH8 xref: UniProtKB:Q9UM10 xref: UniProtKB:Q9UM11 xref: UniProtKB:Q9UNQ1 xref: UniProtKB:Q9Y2T8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004667 ! FZR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008476 ! fzr1-c7orf25 physical interaction relationship: participates_in CCO:I0008477 ! fzr1-dnaja1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011911 ! FZR_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0011912 ! FZR_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0036007 ! FZR_HUMAN-Phosphotyrosine91 relationship: transforms_into CCO:B0036008 ! FZR_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0066333 ! FZR_HUMAN-Phosphothreonine32 relationship: transforms_into CCO:B0066334 ! FZR_HUMAN-Phosphoserine40 relationship: transforms_into CCO:B0066335 ! FZR_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0066336 ! FZR_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0066337 ! FZR_HUMAN-Phosphoserine146 [Term] id: CCO:B0002230 name: APC10_HUMAN def: "Anaphase-promoting complex subunit 10" [UniProtKB:Q9UM13] synonym: "APC10" EXACT [UniProtKB:Q9UM13] synonym: "Cyclosome subunit 10" EXACT [UniProtKB:Q9UM13] xref: EMBL:AAD30527.1 xref: EMBL:AAH05217.1 xref: EMBL:ABB96248.1 xref: EMBL:BAA86953.1 xref: EMBL:CAB45705.1 xref: UniProtKB:Q2V500 xref: UniProtKB:Q9UG51 xref: UniProtKB:Q9UM13 xref: UniProtKB:Q9Y5R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004078 ! ANAPC10_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle relationship: participates_in CCO:P0000020 ! mitotic anaphase relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002231 name: PLAL1_HUMAN def: "Zinc finger protein PLAGL1" [UniProtKB:Q9UM63] synonym: "Lost on transformation 1" EXACT [UniProtKB:Q9UM63] synonym: "LOT-1" EXACT [UniProtKB:Q9UM63] synonym: "Pleiomorphic adenoma-like protein 1" EXACT [UniProtKB:Q9UM63] synonym: "Tumor supressor ZAC" EXACT [UniProtKB:Q9UM63] xref: EMBL:AAB67041.1 xref: EMBL:AAC34250.1 xref: EMBL:AAH74814.1 xref: EMBL:AAI09086.1 xref: EMBL:AAI09087.1 xref: EMBL:CAA06994.1 xref: EMBL:CAB56564.1 xref: EMBL:CAC39614.1 xref: EMBL:CAC39615.1 xref: EMBL:CAD97639.1 xref: EMBL:CAI21447.1 xref: EMBL:EAW47852.1 xref: EMBL:EAW47854.1 xref: UniProtKB:O76019 xref: UniProtKB:Q7Z3V8 xref: UniProtKB:Q92981 xref: UniProtKB:Q96JR9 xref: UniProtKB:Q9UIZ0 xref: UniProtKB:Q9UM63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005332 ! PLAGL1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0002232 name: SUFU_HUMAN def: "Suppressor of fused homolog" [UniProtKB:Q9UMX1] synonym: "SUFUH" EXACT [UniProtKB:Q9UMX1] xref: EMBL:AAD50501.1 xref: EMBL:AAD51655.1 xref: EMBL:AAF23890.1 xref: EMBL:AAF23893.1 xref: EMBL:AAF35866.1 xref: EMBL:AAH13291.1 xref: EMBL:AAM08947.1 xref: EMBL:AAQ88914.1 xref: EMBL:CAB70752.1 xref: EMBL:CAI12525.1 xref: EMBL:CAI12526.1 xref: EMBL:CAI39614.1 xref: EMBL:CAI39615.1 xref: EMBL:CAI40864.1 xref: EMBL:CAI40865.1 xref: UniProtKB:Q7LCP7 xref: UniProtKB:Q9NT90 xref: UniProtKB:Q9NZ07 xref: UniProtKB:Q9UHK2 xref: UniProtKB:Q9UHM8 xref: UniProtKB:Q9UMX1 xref: UniProtKB:Q9UMY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005702 ! SUFU_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005726 ! qprt-sufu physical interaction relationship: participates_in CCO:I0005758 ! glis3-sufu physical interaction relationship: participates_in CCO:I0005826 ! rcn3-sufu physical interaction relationship: participates_in CCO:I0005856 ! sufu-znf446 physical interaction relationship: participates_in CCO:I0005866 ! mgc13138-sufu physical interaction relationship: participates_in CCO:I0005877 ! mid1ip1-sufu physical interaction relationship: participates_in CCO:I0005907 ! sufu-znf263 physical interaction relationship: participates_in CCO:I0005936 ! pex26-sufu physical interaction relationship: participates_in CCO:I0006048 ! stk36-sufu-1 physical interaction relationship: participates_in CCO:I0006049 ! stk36-sufu-2 physical interaction relationship: participates_in CCO:I0007136 ! gli3-sufu-1 direct interaction relationship: participates_in CCO:I0007137 ! sufu-sufu-1 direct interaction relationship: participates_in CCO:I0007889 ! sufu-rcn3 physical interaction relationship: participates_in CCO:I0007890 ! pex26-sufu-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070996 ! SUFU_HUMAN-Phosphoserine481 [Term] id: CCO:B0002233 name: CC14A_HUMAN def: "Dual specificity protein phosphatase CDC14A" [UniProtKB:Q9UNH5] synonym: "CDC14 cell division cycle 14 homolog A" EXACT [UniProtKB:Q9UNH5] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9UNH5] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9UNH5] xref: EMBL:AAB88277.1 xref: EMBL:AAC16659.1 xref: EMBL:AAC16660.1 xref: EMBL:AAD49217.1 xref: EMBL:AAH38979.1 xref: EMBL:AAT38107.1 xref: UniProtKB:O43171 xref: UniProtKB:O60727 xref: UniProtKB:O60728 xref: UniProtKB:Q8IXX0 xref: UniProtKB:Q9UNH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004234 ! CDC14A_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002234 name: ING4_HUMAN def: "Inhibitor of growth protein 4" [UniProtKB:Q9UNL4] synonym: "p29ING4" EXACT [UniProtKB:Q9UNL4] xref: EMBL:AAD48585.1 xref: EMBL:AAG43153.1 xref: EMBL:AAH07781.1 xref: EMBL:AAH13038.2 xref: EMBL:AAL79773.1 xref: UniProtKB:Q96E15 xref: UniProtKB:Q9H3J0 xref: UniProtKB:Q9UNL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004894 ! ING4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012414 ! ING4_HUMAN-N6-acetyllysine127 relationship: transforms_into CCO:B0012415 ! ING4_HUMAN-N6-acetyllysine129 relationship: transforms_into CCO:B0012416 ! ING4_HUMAN-N6-acetyllysine146 relationship: transforms_into CCO:B0012417 ! ING4_HUMAN-N6-acetyllysine148 [Term] id: CCO:B0002235 name: TIM_HUMAN def: "Protein timeless homolog" [UniProtKB:Q9UNS1] synonym: "hTIM" EXACT [UniProtKB:Q9UNS1] xref: EMBL:AAC80011.1 xref: EMBL:AAH39842.1 xref: EMBL:AAH50557.1 xref: EMBL:BAA36499.1 xref: UniProtKB:O94802 xref: UniProtKB:Q86VM1 xref: UniProtKB:Q8IWH3 xref: UniProtKB:Q9UNS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005782 ! TIMELESS_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000117 ! nuclear chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000215 ! regulation of S phase relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014376 ! TIM_HUMAN-Phosphothreonine1089 relationship: transforms_into CCO:B0014377 ! TIM_HUMAN-Phosphoserine1173 [Term] id: CCO:B0002236 name: GP132_HUMAN def: "Probable G-protein coupled receptor 132" [UniProtKB:Q9UNW8] synonym: "G2 accumulation protein" EXACT [UniProtKB:Q9UNW8] xref: EMBL:AAD47380.1 xref: EMBL:AAH84546.1 xref: EMBL:AAP35921.1 xref: UniProtKB:Q9BSU2 xref: UniProtKB:Q9UNW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004718 ! GPR132_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000012 ! G1/S transition of mitotic cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0002237 name: MACF1_HUMAN def: "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" [UniProtKB:Q9UPN3] synonym: "620 kDa actin-binding protein" EXACT [UniProtKB:Q9UPN3] synonym: "ABP620" EXACT [UniProtKB:Q9UPN3] synonym: "Actin cross-linking family protein 7" EXACT [UniProtKB:Q9UPN3] synonym: "Macrophin-1" EXACT [UniProtKB:Q9UPN3] synonym: "Trabeculin-alpha" EXACT [UniProtKB:Q9UPN3] xref: EMBL:AAF06360.1 xref: EMBL:AAL39000.1 xref: EMBL:BAA32310.3 xref: EMBL:BAA83821.1 xref: EMBL:BAA86565.1 xref: EMBL:CAH70156.1 xref: EMBL:CAH73668.1 xref: EMBL:CAI16417.1 xref: EMBL:CAI21814.1 xref: UniProtKB:O75053 xref: UniProtKB:Q5VW20 xref: UniProtKB:Q8WXY2 xref: UniProtKB:Q9H540 xref: UniProtKB:Q9UKP0 xref: UniProtKB:Q9ULG9 xref: UniProtKB:Q9UPN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005012 ! MACF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006589 ! disc1-macf1 physical interaction relationship: participates_in CCO:I0006590 ! disc1-macf1-2 physical interaction relationship: participates_in CCO:I0006591 ! disc1-macf1-3 physical interaction relationship: participates_in CCO:I0006592 ! disc1-macf1-4 physical interaction relationship: participates_in CCO:I0006593 ! dtnbp1-macf1 physical interaction relationship: participates_in CCO:I0006594 ! exoc1-macf1 physical interaction relationship: participates_in CCO:I0006802 ! disc1-macf1-1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0012746 ! MACF1_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0012747 ! MACF1_HUMAN-Phosphoserine1860 relationship: transforms_into CCO:B0012748 ! MACF1_HUMAN-Phosphoserine2454 relationship: transforms_into CCO:B0012749 ! MACF1_HUMAN-Phosphoserine4074 relationship: transforms_into CCO:B0012750 ! MACF1_HUMAN-Phosphoserine5372 relationship: transforms_into CCO:B0012751 ! MACF1_HUMAN-Phosphoserine5375 [Term] id: CCO:B0002238 name: MARE3_HUMAN def: "Microtubule-associated protein RP/EB family member 3" [UniProtKB:Q9UPY8] synonym: "EB1 protein family member 3" EXACT [UniProtKB:Q9UPY8] synonym: "EB3" EXACT [UniProtKB:Q9UPY8] synonym: "EBF3" EXACT [UniProtKB:Q9UPY8] synonym: "End-binding protein 3" EXACT [UniProtKB:Q9UPY8] synonym: "RP3" EXACT [UniProtKB:Q9UPY8] xref: EMBL:AAH11557.1 xref: EMBL:AAK07556.1 xref: EMBL:AAK07557.1 xref: EMBL:BAA82958.1 xref: EMBL:CAA72060.1 xref: EMBL:CAG38760.1 xref: UniProtKB:O00265 xref: UniProtKB:Q6FI15 xref: UniProtKB:Q9BZP7 xref: UniProtKB:Q9BZP8 xref: UniProtKB:Q9UPY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005026 ! MAPRE3_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001017 ! midbody relationship: participates_in CCO:I0005822 ! lmo2-mapre3 physical interaction relationship: participates_in CCO:I0005892 ! mapre2-mapre3 physical interaction relationship: participates_in CCO:I0008492 ! rab1a-mapre3 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012771 ! MARE3_HUMAN-Phosphothreonine161 [Term] id: CCO:B0002239 name: PA2G4_HUMAN def: "Proliferation-associated protein 2G4" [UniProtKB:Q9UQ80] synonym: "Cell cycle protein p38-2G4 homolog" EXACT [UniProtKB:Q9UQ80] synonym: "ErbB3-binding protein 1" EXACT [UniProtKB:Q9UQ80] synonym: "hG4-1" EXACT [UniProtKB:Q9UQ80] xref: EMBL:AAB91536.1 xref: EMBL:AAD00646.1 xref: EMBL:AAD05561.1 xref: EMBL:AAH01951.1 xref: EMBL:AAH07561.1 xref: EMBL:AAH69786.1 xref: UniProtKB:O43846 xref: UniProtKB:Q9UM59 xref: UniProtKB:Q9UQ80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005252 ! PA2G4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006052 ! pa2g4-rb1-1 physical interaction relationship: participates_in CCO:I0006053 ! rb1-pa2g4-2 physical interaction relationship: participates_in CCO:I0006054 ! pa2g4-rb1-2 physical interaction relationship: participates_in CCO:I0006055 ! pa2g4-e2f1-1 physical interaction relationship: participates_in CCO:I0006345 ! pa2g4-npm-1 colocalization relationship: participates_in CCO:I0006346 ! pa2g4-npm-2 colocalization relationship: participates_in CCO:I0007143 ! erbb3-pa2g4-1 physical interaction relationship: participates_in CCO:I0007144 ! pa2g4-ar-1 physical interaction relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007294 ! pa2g4-ncl-1 physical interaction relationship: participates_in CCO:I0007418 ! rb1-pa2g4-1 physical interaction relationship: participates_in CCO:I0007916 ! pa2g4-hdac2-1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013365 ! PA2G4_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0013366 ! PA2G4_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0013367 ! PA2G4_HUMAN-Phosphothreonine366 relationship: transforms_into CCO:B0013368 ! PA2G4_HUMAN-Phosphothreonine386 relationship: transforms_into CCO:B0069043 ! PA2G4_HUMAN-Phosphoserine361 [Term] id: CCO:B0002240 name: EXO1_HUMAN def: "Exonuclease 1" [UniProtKB:Q9UQ84] synonym: "EC 3.1.-.-" EXACT [UniProtKB:Q9UQ84] synonym: "Exonuclease I" EXACT [UniProtKB:Q9UQ84] synonym: "hExo1" EXACT [UniProtKB:Q9UQ84] synonym: "hExoI" EXACT [UniProtKB:Q9UQ84] xref: EMBL:AAC32259.1 xref: EMBL:AAC32424.1 xref: EMBL:AAC33874.1 xref: EMBL:AAC63043.1 xref: EMBL:AAC69879.1 xref: EMBL:AAC69880.1 xref: EMBL:AAD13754.1 xref: EMBL:AAH07491.1 xref: EMBL:AAN39382.1 xref: EMBL:CAB45733.1 xref: EMBL:CAI15658.1 xref: UniProtKB:O60545 xref: UniProtKB:O75214 xref: UniProtKB:O75466 xref: UniProtKB:Q5T396 xref: UniProtKB:Q96IJ1 xref: UniProtKB:Q9UG38 xref: UniProtKB:Q9UNW0 xref: UniProtKB:Q9UQ84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004594 ! EXO1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001876 ! 5'-3' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005595 ! 5'-3' exodeoxyribonuclease activity relationship: has_function CCO:F0006082 ! single-stranded DNA specific 5'-3' exodeoxyribonuclease activity relationship: has_function CCO:F0007325 ! flap endonuclease activity relationship: has_function CCO:F0008206 ! double-stranded DNA specific 5'-3' exodeoxyribonuclease activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0011807 ! EXO1_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0011808 ! EXO1_HUMAN-Phosphoserine714 relationship: transforms_into CCO:B0065180 ! EXO1_HUMAN-Phosphoserine422 [Term] id: CCO:B0002241 name: CD2L2_HUMAN def: "PITSLRE serine/threonine-protein kinase CDC2L2" [UniProtKB:Q9UQ88] synonym: "CDK11" EXACT [UniProtKB:Q9UQ88] synonym: "Cell division cycle 2-like protein kinase 2" EXACT [UniProtKB:Q9UQ88] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q9UQ88] synonym: "Galactosyltransferase-associated protein kinase p58/GTA" EXACT [UniProtKB:Q9UQ88] xref: EMBL:AAA19585.1 xref: EMBL:AAA19594.1 xref: EMBL:AAA19595.1 xref: EMBL:AAC72083.1 xref: EMBL:AAC72084.1 xref: EMBL:AAC72085.1 xref: EMBL:AAC72086.1 xref: EMBL:AAC72087.1 xref: EMBL:AAC72088.1 xref: EMBL:AAC72089.1 xref: EMBL:AAC72090.1 xref: EMBL:AAC72091.1 xref: EMBL:AAC72092.1 xref: EMBL:AAC72093.1 xref: EMBL:AAC72094.1 xref: EMBL:AAC95297.1 xref: EMBL:AAC95298.1 xref: EMBL:AAC95299.1 xref: EMBL:AAC95300.1 xref: EMBL:AAC95302.1 xref: EMBL:AAC95303.1 xref: EMBL:CAI20032.1 xref: EMBL:CAI20033.1 xref: EMBL:CAI20034.1 xref: UniProtKB:O95227 xref: UniProtKB:O95228 xref: UniProtKB:O96012 xref: UniProtKB:Q12821 xref: UniProtKB:Q12853 xref: UniProtKB:Q12854 xref: UniProtKB:Q5QPR0 xref: UniProtKB:Q5QPR1 xref: UniProtKB:Q5QPR2 xref: UniProtKB:Q9UBC4 xref: UniProtKB:Q9UBI3 xref: UniProtKB:Q9UEI1 xref: UniProtKB:Q9UEI2 xref: UniProtKB:Q9UP53 xref: UniProtKB:Q9UP54 xref: UniProtKB:Q9UP55 xref: UniProtKB:Q9UP56 xref: UniProtKB:Q9UQ86 xref: UniProtKB:Q9UQ87 xref: UniProtKB:Q9UQ88 xref: UniProtKB:Q9UQ89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004274 ! CDC2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006494 ! skiv2l-cdc2l2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002925 ! regulation of mRNA processing relationship: transforms_into CCO:B0011025 ! CD2L2_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0011026 ! CD2L2_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0011027 ! CD2L2_HUMAN-Phosphothreonine433 relationship: transforms_into CCO:B0011028 ! CD2L2_HUMAN-Phosphotyrosine434 relationship: transforms_into CCO:B0011029 ! CD2L2_HUMAN-Phosphothreonine580 relationship: transforms_into CCO:B0011030 ! CD2L2_HUMAN-Phosphothreonine736 relationship: transforms_into CCO:B0011031 ! CD2L2_HUMAN-Phosphoserine737 relationship: transforms_into CCO:B0064146 ! CD2L2_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0064147 ! CD2L2_HUMAN-Phosphoserine574 relationship: transforms_into CCO:B0064148 ! CD2L2_HUMAN-Phosphothreonine758 [Term] id: CCO:B0002242 name: AURKC_HUMAN def: "Serine/threonine-protein kinase 13" [UniProtKB:Q9UQB9] synonym: "Aurora-C" EXACT [UniProtKB:Q9UQB9] synonym: "Aurora/Ipl1-related kinase 3" EXACT [UniProtKB:Q9UQB9] synonym: "Aurora/Ipl1/Eg2 protein 2" EXACT [UniProtKB:Q9UQB9] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UQB9] xref: EMBL:AAC25955.1 xref: EMBL:AAC77369.1 xref: EMBL:BAA76292.1 xref: UniProtKB:O60681 xref: UniProtKB:O75442 xref: UniProtKB:Q9UPK5 xref: UniProtKB:Q9UQB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004130 ! AURKC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000453 ! cytokinesis [Term] id: CCO:B0002243 name: SMC3_HUMAN def: "Structural maintenance of chromosomes protein 3" [UniProtKB:Q9UQE7] synonym: "Bamacan" EXACT [UniProtKB:Q9UQE7] synonym: "Basement membrane-associated chondroitin proteoglycan" EXACT [UniProtKB:Q9UQE7] synonym: "Chondroitin sulfate proteoglycan 6" EXACT [UniProtKB:Q9UQE7] synonym: "Chromosome-associated polypeptide" EXACT [UniProtKB:Q9UQE7] synonym: "hCAP" EXACT [UniProtKB:Q9UQE7] xref: EMBL:AAC14893.1 xref: EMBL:AAD32447.1 xref: EMBL:CAA06289.1 xref: EMBL:CAI16576.1 xref: UniProtKB:O60464 xref: UniProtKB:Q5T482 xref: UniProtKB:Q9UQE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005628 ! SMC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006578 ! cep63-cspg6 physical interaction relationship: participates_in CCO:I0007036 ! wapl-cspg6 physical interaction relationship: participates_in CCO:I0007037 ! wapl-cspg6-3 physical interaction relationship: participates_in CCO:I0007039 ! wapl-cspg6-1 physical interaction relationship: participates_in CCO:I0007040 ! wapl-cspg6-2 physical interaction relationship: participates_in CCO:I0007177 ! cspg6-rad21 physical interaction relationship: participates_in CCO:I0007711 ! wapl-cspg6-4 physical interaction relationship: participates_in CCO:I0007712 ! wapl-cspg6-5 physical interaction relationship: participates_in CCO:I0007713 ! wapl-cspg6-6 physical interaction relationship: participates_in CCO:I0007714 ! wapl-cspg6-7 physical interaction relationship: participates_in CCO:I0007715 ! wapl-cspg6-9 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000068 ! mitotic spindle organization and biogenesis relationship: participates_in CCO:P0000076 ! sister chromatid cohesion relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: transforms_into CCO:B0014077 ! SMC3_HUMAN-Phosphoserine1013 relationship: transforms_into CCO:B0014078 ! SMC3_HUMAN-Phosphoserine1065 relationship: transforms_into CCO:B0014079 ! SMC3_HUMAN-Phosphoserine1067 relationship: transforms_into CCO:B0014080 ! SMC3_HUMAN-Phosphoserine1074 relationship: transforms_into CCO:B0014081 ! SMC3_HUMAN-Phosphoserine1083 [Term] id: CCO:B0002244 name: HDAC5_HUMAN def: "Histone deacetylase 5" [UniProtKB:Q9UQL6] synonym: "Antigen NY-CO-9" EXACT [UniProtKB:Q9UQL6] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q9UQL6] synonym: "HD5" EXACT [UniProtKB:Q9UQL6] xref: EMBL:AAC18040.1 xref: EMBL:AAD29047.1 xref: EMBL:AAH13140.1 xref: EMBL:AAH51824.1 xref: EMBL:BAA25526.2 xref: EMBL:DAA00017.1 xref: UniProtKB:O60340 xref: UniProtKB:O60528 xref: UniProtKB:Q96DY4 xref: UniProtKB:Q9UQL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004790 ! HDAC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006824 ! brms1-hdac5 physical interaction relationship: participates_in CCO:I0007193 ! hdac5-brms1 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0008248 ! hdac5-gabarap physical interaction relationship: participates_in CCO:I0008394 ! hdac5-eef1g physical interaction relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012166 ! HDAC5_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0012167 ! HDAC5_HUMAN-Phosphoserine498 [Term] id: CCO:B0002245 name: JAG2_HUMAN def: "Protein jagged-2 precursor" [UniProtKB:Q9Y219] synonym: "HJ2" EXACT [UniProtKB:Q9Y219] synonym: "Jagged2" EXACT [UniProtKB:Q9Y219] xref: EMBL:AAB61285.1 xref: EMBL:AAB71189.1 xref: EMBL:AAB84215.1 xref: EMBL:AAB84216.1 xref: EMBL:AAD15562.1 xref: EMBL:CAA74706.1 xref: UniProtKB:Q9UE17 xref: UniProtKB:Q9UE99 xref: UniProtKB:Q9UNK8 xref: UniProtKB:Q9Y219 xref: UniProtKB:Q9Y6P9 xref: UniProtKB:Q9Y6Q0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004907 ! JAG2_human relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006217 ! gfi1b-jag2 physical interaction relationship: participates_in CCO:I0007614 ! atn1-jag2 physical interaction relationship: participates_in CCO:I0007615 ! atn1-jag2-1 physical interaction relationship: participates_in CCO:I0007653 ! gfi1b-jag2-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0002246 name: OSGI2_HUMAN def: "Oxidative stress-induced growth inhibitor 2" [UniProtKB:Q9Y236] synonym: "hT41" EXACT [UniProtKB:Q9Y236] xref: EMBL:AAC62231.1 xref: EMBL:AAD18134.1 xref: EMBL:AAH31054.2 xref: UniProtKB:Q9Y236 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005239 ! OSGIN2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0002247 name: DLEC1_HUMAN def: "Deleted in lung and esophageal cancer protein 1" [UniProtKB:Q9Y238] synonym: "Deleted in lung cancer protein 1" EXACT [UniProtKB:Q9Y238] synonym: "DLC-1" EXACT [UniProtKB:Q9Y238] xref: EMBL:BAA77247.1 xref: EMBL:BAA77624.1 xref: EMBL:CAB70676.1 xref: EMBL:CAB70884.2 xref: UniProtKB:Q9NSW0 xref: UniProtKB:Q9NTG5 xref: UniProtKB:Q9Y238 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004477 ! DLEC1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0002248 name: LZTS1_HUMAN def: "Leucine zipper putative tumor suppressor 1" [UniProtKB:Q9Y250] synonym: "F37/esophageal cancer-related gene-coding leucine-zipper motif" EXACT [UniProtKB:Q9Y250] synonym: "Fez1" EXACT [UniProtKB:Q9Y250] xref: EMBL:AAD23833.1 xref: EMBL:AAD23834.1 xref: EMBL:AAD23835.1 xref: EMBL:AAD23836.1 xref: EMBL:AAD23837.1 xref: EMBL:AAD23838.1 xref: EMBL:AAD23839.1 xref: EMBL:AAD23840.1 xref: EMBL:AAH75006.1 xref: EMBL:AAH75007.1 xref: UniProtKB:Q9Y250 xref: UniProtKB:Q9Y5V7 xref: UniProtKB:Q9Y5V8 xref: UniProtKB:Q9Y5V9 xref: UniProtKB:Q9Y5W0 xref: UniProtKB:Q9Y5W1 xref: UniProtKB:Q9Y5W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005000 ! LZTS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0002249 name: RUVB1_HUMAN def: "RuvB-like 1" [UniProtKB:Q9Y265] synonym: "49 kDa TATA box-binding protein-interacting protein" EXACT [UniProtKB:Q9Y265] synonym: "49 kDa TBP-interacting protein" EXACT [UniProtKB:Q9Y265] synonym: "54 kDa erythrocyte cytosolic protein" EXACT [UniProtKB:Q9Y265] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9Y265] synonym: "ECP-54" EXACT [UniProtKB:Q9Y265] synonym: "INO80 complex subunit H" EXACT [UniProtKB:Q9Y265] synonym: "NMP 238" EXACT [UniProtKB:Q9Y265] synonym: "Nuclear matrix protein 238" EXACT [UniProtKB:Q9Y265] synonym: "Pontin 52" EXACT [UniProtKB:Q9Y265] synonym: "TAP54-alpha" EXACT [UniProtKB:Q9Y265] synonym: "TIP49a" EXACT [UniProtKB:Q9Y265] synonym: "TIP60-associated protein 54-alpha" EXACT [UniProtKB:Q9Y265] xref: EMBL:AAC77819.1 xref: EMBL:AAD04427.1 xref: EMBL:AAH02993.1 xref: EMBL:AAH12886.1 xref: EMBL:AAM45570.1 xref: EMBL:AAP35706.1 xref: EMBL:ABF13334.1 xref: EMBL:BAA28169.1 xref: EMBL:BAD96283.1 xref: EMBL:BAD96295.1 xref: EMBL:CAA08986.1 xref: EMBL:CAB46271.1 xref: UniProtKB:P82276 xref: UniProtKB:Q1KMR0 xref: UniProtKB:Q53HK5 xref: UniProtKB:Q53HL7 xref: UniProtKB:Q53Y27 xref: UniProtKB:Q9BSX9 xref: UniProtKB:Q9Y265 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005548 ! RUVBL1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0001626 ! NuA4 histone acetyltransferase complex relationship: participates_in CCO:I0006019 ! htatip-trrap-1 physical interaction relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006037 ! znf-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0006354 ! map3k8-ruvbl1 physical interaction relationship: participates_in CCO:I0006359 ! ikbke-ruvbl1 physical interaction relationship: participates_in CCO:I0006378 ! map3k3-ruvbl1 physical interaction relationship: participates_in CCO:I0006389 ! map3k14-ruvbl1 physical interaction relationship: participates_in CCO:I0006393 ! relb-ruvbl1 physical interaction relationship: participates_in CCO:I0006405 ! map3k7ip1-ruvbl1 physical interaction relationship: participates_in CCO:I0006408 ! q9nyj8-ruvbl1 physical interaction relationship: participates_in CCO:I0006410 ! tbk1-ruvbl1 physical interaction relationship: participates_in CCO:I0006413 ! tnfrsf1a-ruvbl1 physical interaction relationship: participates_in CCO:I0006417 ! traf2-ruvbl1 physical interaction relationship: participates_in CCO:I0006510 ! ruvbl1-ruvbl2-1 physical interaction relationship: participates_in CCO:I0006982 ! tcfcl1-ruvbl1 physical interaction relationship: participates_in CCO:I0006983 ! tcfcl1-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006984 ! tcfcl1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006985 ! tcfcl1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007773 ! znf-ruvbl physical interaction relationship: participates_in CCO:I0007774 ! znhit4-ruvbl-1 physical interaction relationship: participates_in CCO:I0007775 ! actr8-ruvbl physical interaction relationship: participates_in CCO:I0007777 ! mcrs1-ruvbl physical interaction relationship: participates_in CCO:I0007778 ! fj90652-ruvbl-1 physical interaction relationship: participates_in CCO:I0007779 ! flj20309-ruvbl-2 physical interaction relationship: participates_in CCO:I0007780 ! mrgbp-ruvbl1-2 physical interaction relationship: participates_in CCO:I0007781 ! tcfl1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0007782 ! znf-ruvbl1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008432 ! ruvbl1-kiaa1377 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0002250 name: NUDC_HUMAN def: "Nuclear migration protein nudC" [UniProtKB:Q9Y266] synonym: "Nuclear distribution protein C homolog" EXACT [UniProtKB:Q9Y266] xref: EMBL:AAD30517.1 xref: EMBL:AAD39921.1 xref: EMBL:AAD43024.1 xref: EMBL:AAH02399.1 xref: EMBL:AAH03132.1 xref: EMBL:AAH06147.1 xref: EMBL:AAH07280.1 xref: EMBL:AAH15153.1 xref: EMBL:AAH21139.1 xref: EMBL:AAP97152.1 xref: EMBL:BAA76628.1 xref: EMBL:CAB66659.1 xref: EMBL:CAI13560.1 xref: EMBL:CAI13561.1 xref: EMBL:CAI13563.1 xref: UniProtKB:Q5QP31 xref: UniProtKB:Q5QP35 xref: UniProtKB:Q9H0N2 xref: UniProtKB:Q9Y266 xref: UniProtKB:Q9Y2B6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005223 ! NUDC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006381 ! map3k3-nudc physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0013286 ! NUDC_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0013287 ! NUDC_HUMAN-Phosphothreonine145 relationship: transforms_into CCO:B0013288 ! NUDC_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0013289 ! NUDC_HUMAN-Phosphoserine285 relationship: transforms_into CCO:B0013290 ! NUDC_HUMAN-Phosphoserine326 [Term] id: CCO:B0002251 name: ATF5_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-5" [UniProtKB:Q9Y2D1] synonym: "Activating transcription factor 5" EXACT [UniProtKB:Q9Y2D1] synonym: "Transcription factor ATFx" EXACT [UniProtKB:Q9Y2D1] xref: EMBL:AAD28370.1 xref: EMBL:AAG22558.1 xref: EMBL:AAH05174.1 xref: EMBL:BAA78477.2 xref: EMBL:BAD38650.1 xref: UniProtKB:Q9BSA1 xref: UniProtKB:Q9UNQ3 xref: UniProtKB:Q9Y2D1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004115 ! ATF5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006284 ! trib3-atf5-1 physical interaction relationship: participates_in CCO:I0006722 ! disc1-atf5-6 colocalization relationship: participates_in CCO:I0006889 ! disc1-atf5-3 physical interaction relationship: participates_in CCO:I0006997 ! disc1-atf5 physical interaction relationship: participates_in CCO:I0006998 ! disc1-atf5-5 physical interaction relationship: participates_in CCO:I0007293 ! disc1-atf5-1 physical interaction relationship: participates_in CCO:I0007371 ! disc1-atf5-4 physical interaction relationship: participates_in CCO:I0007420 ! disc1-atf5-2 physical interaction relationship: participates_in CCO:I0007789 ! disc1-atf5-7 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0002252 name: SUGT1_HUMAN def: "Suppressor of G2 allele of SKP1 homolog" [UniProtKB:Q9Y2Z0] synonym: "Putative 40-6-3 protein" EXACT [UniProtKB:Q9Y2Z0] synonym: "Sgt1" EXACT [UniProtKB:Q9Y2Z0] xref: EMBL:AAD30062.1 xref: EMBL:AAH00911.1 xref: EMBL:AAP88800.1 xref: EMBL:AAQ01749.1 xref: EMBL:AAQ76039.1 xref: EMBL:CAC51433.1 xref: UniProtKB:Q5JAK5 xref: UniProtKB:Q6VXY6 xref: UniProtKB:Q9Y2Z0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005703 ! SUGT1_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000103 ! kinetochore relationship: participates_in CCO:I0006374 ! map3k3-sugt1 physical interaction relationship: participates_in CCO:P0000081 ! mitosis relationship: transforms_into CCO:B0014270 ! SUGT1_HUMAN-Phosphothreonine265 relationship: transforms_into CCO:B0014271 ! SUGT1_HUMAN-Phosphotyrosine317 relationship: transforms_into CCO:B0041342 ! SUGT1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0002253 name: STA13_HUMAN def: "StAR-related lipid transfer protein 13" [UniProtKB:Q9Y3M8] synonym: "46H23.2" EXACT [UniProtKB:Q9Y3M8] synonym: "Deleted in liver cancer protein 2" EXACT [UniProtKB:Q9Y3M8] synonym: "Rho GTPase-activating protein" EXACT [UniProtKB:Q9Y3M8] synonym: "StARD13" EXACT [UniProtKB:Q9Y3M8] synonym: "START domain-containing protein 13" EXACT [UniProtKB:Q9Y3M8] xref: EMBL:AAH46563.1 xref: EMBL:AAL91648.1 xref: EMBL:AAL91649.1 xref: EMBL:AAL91650.1 xref: EMBL:AAQ72791.1 xref: EMBL:CAB42562.1 xref: EMBL:CAC94774.1 xref: EMBL:CAI46026.1 xref: EMBL:CAM17900.1 xref: EMBL:CAM23625.1 xref: EMBL:CAM23626.1 xref: UniProtKB:A2A309 xref: UniProtKB:A2A310 xref: UniProtKB:Q5HYH1 xref: UniProtKB:Q5TAE3 xref: UniProtKB:Q6UN61 xref: UniProtKB:Q86TP6 xref: UniProtKB:Q86WQ3 xref: UniProtKB:Q86XT1 xref: UniProtKB:Q9Y3M8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005680 ! STARD13_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000382 ! lipid particle relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: located_in CCO:C0002166 ! monolayer-surrounded lipid storage body outer lipid monolayer relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0002254 name: RBGP1_HUMAN def: "Rab GTPase-activating protein 1" [UniProtKB:Q9Y3P9] synonym: "GAP and centrosome-associated protein" EXACT [UniProtKB:Q9Y3P9] synonym: "Rab6 GTPase-activating protein GAPCenA" EXACT [UniProtKB:Q9Y3P9] xref: EMBL:AAF28917.1 xref: EMBL:AAH20609.1 xref: EMBL:AAH54492.1 xref: EMBL:BAB14031.1 xref: EMBL:BAD18594.1 xref: EMBL:CAB40267.2 xref: EMBL:CAB43313.1 xref: EMBL:CAH70298.2 xref: UniProtKB:Q05CW2 xref: UniProtKB:Q6ZMY1 xref: UniProtKB:Q9HA28 xref: UniProtKB:Q9P0E2 xref: UniProtKB:Q9UG67 xref: UniProtKB:Q9Y3P9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005444 ! RABGAP1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0069776 ! RBGP1_HUMAN-Phosphothreonine996 [Term] id: CCO:B0002255 name: RBM7_HUMAN def: "RNA-binding protein 7" [UniProtKB:Q9Y580] synonym: "RNA-binding motif protein 7" EXACT [UniProtKB:Q9Y580] xref: EMBL:AAD39257.1 xref: EMBL:AAH34381.1 xref: EMBL:BAA92036.1 xref: UniProtKB:Q9NUT4 xref: UniProtKB:Q9Y580 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005449 ! RBM7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005804 ! hnrpk-rbm7 physical interaction relationship: participates_in CCO:I0005840 ! rbm7-rbmx physical interaction relationship: participates_in CCO:I0005865 ! khdrbs3-rbm7 physical interaction relationship: participates_in CCO:I0005906 ! hmg20a-rbm7 physical interaction relationship: participates_in CCO:P0000117 ! meiosis relationship: transforms_into CCO:B0013793 ! RBM7_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0013794 ! RBM7_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0069822 ! RBM7_HUMAN-Phosphoserine134 [Term] id: CCO:B0002256 name: SPO11_HUMAN def: "Meiotic recombination protein SPO11" [UniProtKB:Q9Y5K1] synonym: "Cancer/testis antigen 35" EXACT [UniProtKB:Q9Y5K1] synonym: "CT35" EXACT [UniProtKB:Q9Y5K1] xref: EMBL:AAD44812.1 xref: EMBL:AAD52562.1 xref: EMBL:AAH33591.1 xref: EMBL:AAX44047.1 xref: EMBL:CAI21521.1 xref: EMBL:CAI21522.1 xref: UniProtKB:Q5TCI1 xref: UniProtKB:Q8N4V0 xref: UniProtKB:Q9NQM7 xref: UniProtKB:Q9NQM8 xref: UniProtKB:Q9Y5K1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005664 ! SPO11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0002257 name: CD2AP_HUMAN def: "CD2-associated protein" [UniProtKB:Q9Y5K6] synonym: "Adapter protein CMS" EXACT [UniProtKB:Q9Y5K6] synonym: "Cas ligand with multiple SH3 domains" EXACT [UniProtKB:Q9Y5K6] xref: EMBL:AAD34595.1 xref: EMBL:AAF80495.1 xref: EMBL:AAH69444.1 xref: EMBL:CAB43274.1 xref: EMBL:CAH73238.1 xref: EMBL:CAI16839.1 xref: EMBL:EAX04319.1 xref: UniProtKB:A6NL34 xref: UniProtKB:Q5VYA3 xref: UniProtKB:Q9UG97 xref: UniProtKB:Q9Y5K6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004272 ! CD2AP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006843 ! sos1-cd2ap-1 physical interaction relationship: participates_in CCO:I0006844 ! sos2-cd2ap-1 physical interaction relationship: participates_in CCO:I0007331 ! hck-cd2ap-1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002801 ! regulation of receptor-mediated endocytosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011016 ! CD2AP_HUMAN-Phosphotyrosine88 relationship: transforms_into CCO:B0011017 ! CD2AP_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0041128 ! CD2AP_HUMAN-Phosphoserine458 relationship: transforms_into CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 [Term] id: CCO:B0002258 name: P2R3B_HUMAN def: "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta" [UniProtKB:Q9Y5P8] synonym: "PP2A, subunit B, PR48 isoform" EXACT [UniProtKB:Q9Y5P8] synonym: "Protein phosphatase 2A 48 kDa regulatory subunit" EXACT [UniProtKB:Q9Y5P8] xref: EMBL:AAD38515.1 xref: EMBL:AAH63429.1 xref: EMBL:DAA00385.1 xref: UniProtKB:Q6P4G9 xref: UniProtKB:Q7RTT1 xref: UniProtKB:Q9Y5P8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005241 ! PPP2R3B_human relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0069012 ! P2R3B_HUMAN-Phosphotyrosine184 [Term] id: CCO:B0002259 name: UBP16_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 16" [UniProtKB:Q9Y5T5] synonym: "Deubiquitinating enzyme 16" EXACT [UniProtKB:Q9Y5T5] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q9Y5T5] synonym: "Ubiquitin thioesterase 16" EXACT [UniProtKB:Q9Y5T5] synonym: "Ubiquitin-processing protease UBP-M" EXACT [UniProtKB:Q9Y5T5] synonym: "Ubiquitin-specific-processing protease 16" EXACT [UniProtKB:Q9Y5T5] xref: EMBL:AAD20949.1 xref: EMBL:AAH30777.1 xref: EMBL:CAB90432.1 xref: UniProtKB:Q8NEL3 xref: UniProtKB:Q9Y5T5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005868 ! USP16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0014567 ! UBP16_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0071678 ! UBP16_HUMAN-Phosphoserine415 [Term] id: CCO:B0002260 name: RA54B_HUMAN def: "DNA repair and recombination protein RAD54B" [UniProtKB:Q9Y620] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9Y620] synonym: "RAD54 homolog B" EXACT [UniProtKB:Q9Y620] xref: EMBL:AAD34331.1 xref: EMBL:AAH01965.1 xref: UniProtKB:Q9Y620 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005408 ! RAD54B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005793 ! rad54b-znf580 physical interaction relationship: participates_in CCO:I0005801 ! cdc23-rad54b physical interaction relationship: participates_in CCO:I0005813 ! gorasp2-rad54b physical interaction relationship: participates_in CCO:I0005817 ! psma1-rad54b physical interaction relationship: participates_in CCO:I0005835 ! myo15b-rad54b physical interaction relationship: participates_in CCO:I0005852 ! dyrk2-rad54b physical interaction relationship: participates_in CCO:I0005861 ! csnk1e-rad54b physical interaction relationship: participates_in CCO:I0005875 ! rad54b-ube2i physical interaction relationship: participates_in CCO:I0005882 ! rad54b-ribc2 physical interaction relationship: participates_in CCO:I0005913 ! rad54b-rad54b physical interaction relationship: participates_in CCO:I0005923 ! lnx-rad54b physical interaction relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0002262 name: SPIN1_HUMAN def: "Spindlin-1" [UniProtKB:Q9Y657] synonym: "Ovarian cancer-related protein" EXACT [UniProtKB:Q9Y657] xref: EMBL:AAD43035.1 xref: EMBL:AAG38112.1 xref: EMBL:AAG48367.1 xref: EMBL:AAI14516.1 xref: EMBL:AAI14566.1 xref: EMBL:AAP35978.1 xref: EMBL:CAB66653.1 xref: EMBL:CAG38515.1 xref: EMBL:CAH72406.1 xref: UniProtKB:Q7KZJ8 xref: UniProtKB:Q9GZT2 xref: UniProtKB:Q9H0N7 xref: UniProtKB:Q9Y657 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005663 ! SPIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008506 ! spin-ptn physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0014176 ! SPIN1_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0014177 ! SPIN1_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0048399 ! SPIN1_HUMAN-Phosphotyrosine91 relationship: transforms_into CCO:B0048400 ! SPIN1_HUMAN-Phosphotyrosine98 relationship: transforms_into CCO:B0070799 ! SPIN1_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0070800 ! SPIN1_HUMAN-Phosphoserine199 [Term] id: CCO:B0002263 name: EID1_HUMAN def: "EP300-interacting inhibitor of differentiation 1" [UniProtKB:Q9Y6B2] synonym: "21 kDa pRb-associated protein" EXACT [UniProtKB:Q9Y6B2] synonym: "CREBBP/EP300 inhibitory protein 1" EXACT [UniProtKB:Q9Y6B2] synonym: "E1A-like inhibitor of differentiation 1" EXACT [UniProtKB:Q9Y6B2] synonym: "EID-1" EXACT [UniProtKB:Q9Y6B2] xref: EMBL:AAD40377.1 xref: EMBL:AAG35179.1 xref: EMBL:AAI14945.1 xref: EMBL:AAI14947.1 xref: EMBL:AAK07524.1 xref: EMBL:AAK29640.1 xref: EMBL:BAC05296.1 xref: EMBL:CAB52022.1 xref: EMBL:CAB93108.1 xref: UniProtKB:Q8N7I4 xref: UniProtKB:Q9BZT9 xref: UniProtKB:Q9Y6B2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004557 ! EID1_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0005558 ! histone acetyltransferase regulator activity relationship: has_function CCO:F0005559 ! histone acetyltransferase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0036000 ! EID1_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0036001 ! EID1_HUMAN-Phosphoserine8 [Term] id: CCO:B0002264 name: MD1L1_HUMAN def: "Mitotic spindle assembly checkpoint protein MAD1" [UniProtKB:Q9Y6D9] synonym: "hMAD1" EXACT [UniProtKB:Q9Y6D9] synonym: "HsMAD1" EXACT [UniProtKB:Q9Y6D9] synonym: "MAD1-like 1" EXACT [UniProtKB:Q9Y6D9] synonym: "Mitotic arrest deficient-like protein 1" EXACT [UniProtKB:Q9Y6D9] synonym: "Mitotic checkpoint MAD1 protein-homolog" EXACT [UniProtKB:Q9Y6D9] synonym: "Tax-binding protein 181" EXACT [UniProtKB:Q9Y6D9] xref: EMBL:AAC52059.1 xref: EMBL:AAD20359.1 xref: EMBL:AAD24498.1 xref: EMBL:AAH09964.1 xref: EMBL:AAP21876.1 xref: EMBL:AAS07503.1 xref: UniProtKB:Q13312 xref: UniProtKB:Q75MI0 xref: UniProtKB:Q86UM4 xref: UniProtKB:Q9UNH0 xref: UniProtKB:Q9Y6D9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005046 ! MAD1L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005743 ! mad1l1-tex11 physical interaction relationship: participates_in CCO:I0005803 ! mad1l1-nono physical interaction relationship: participates_in CCO:I0005894 ! c1orf117-mad1l1 physical interaction relationship: participates_in CCO:I0005905 ! mad1l1-trim29 physical interaction relationship: participates_in CCO:I0005912 ! amotl2-mad1l1 physical interaction relationship: participates_in CCO:I0005927 ! mad1l1-q9bvr6 physical interaction relationship: participates_in CCO:I0005953 ! mad1l1-mad1l1 physical interaction relationship: participates_in CCO:I0005960 ! mad1l1-mad2l1 physical interaction relationship: participates_in CCO:I0006649 ! mad1l1-coil physical interaction relationship: participates_in CCO:I0006751 ! mad1l1_zw10_1 colocalization relationship: participates_in CCO:P0000019 ! mitotic metaphase relationship: participates_in CCO:P0000020 ! mitotic anaphase relationship: participates_in CCO:P0000023 ! mitotic telophase relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0012844 ! MD1L1_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0012845 ! MD1L1_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0068077 ! MD1L1_HUMAN-Phosphoserine16 [Term] id: CCO:B0002265 name: USH1C_HUMAN def: "Harmonin" [UniProtKB:Q9Y6N9] synonym: "Antigen NY-CO-38/NY-CO-37" EXACT [UniProtKB:Q9Y6N9] synonym: "Autoimmune enteropathy-related antigen AIE-75" EXACT [UniProtKB:Q9Y6N9] synonym: "PDZ-73 protein" EXACT [UniProtKB:Q9Y6N9] synonym: "Renal carcinoma antigen NY-REN-3" EXACT [UniProtKB:Q9Y6N9] synonym: "Usher syndrome type-1C protein" EXACT [UniProtKB:Q9Y6N9] xref: EMBL:AAC18048.1 xref: EMBL:AAC18049.1 xref: EMBL:AAH16057.1 xref: EMBL:BAA81739.1 xref: EMBL:BAA81740.1 xref: UniProtKB:Q96B29 xref: UniProtKB:Q9UM04 xref: UniProtKB:Q9UM17 xref: UniProtKB:Q9UPC3 xref: UniProtKB:Q9Y6N9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005888 ! USH1C_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000185 ! photoreceptor outer segment relationship: located_in CCO:C0000188 ! photoreceptor inner segment relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001446 ! stereocilium relationship: located_in CCO:C0001896 ! apical part of cell relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:P0000016 ! G2/M transition of mitotic cell cycle [Term] id: CCO:B0002266 name: SESN1_HUMAN def: "Sestrin-1" [UniProtKB:Q9Y6P5] synonym: "p53-regulated protein PA26" EXACT [UniProtKB:Q9Y6P5] xref: EMBL:AAD04810.1 xref: EMBL:AAD04811.1 xref: EMBL:AAD04812.1 xref: EMBL:AAI12037.1 xref: EMBL:AAI13570.1 xref: EMBL:BAA91961.1 xref: EMBL:EAW48368.1 xref: UniProtKB:Q2M2B7 xref: UniProtKB:Q9NV00 xref: UniProtKB:Q9UPD5 xref: UniProtKB:Q9Y6P5 xref: UniProtKB:Q9Y6P6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005593 ! SESN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0014017 ! SESN1_HUMAN-Phosphoserine293 [Term] id: CCO:B0002267 name: MYO16_HUMAN def: "Myosin-XVI" [UniProtKB:Q9Y6X6] synonym: "Unconventional myosin-16" EXACT [UniProtKB:Q9Y6X6] xref: EMBL:BAA74888.2 xref: EMBL:BAC04608.1 xref: EMBL:BAC87143.1 xref: EMBL:CAD39107.2 xref: EMBL:CAH70519.1 xref: EMBL:CAH70520.1 xref: EMBL:CAH70521.1 xref: EMBL:CAH73221.1 xref: EMBL:CAH73222.1 xref: EMBL:CAH73223.1 xref: EMBL:CAI15548.1 xref: EMBL:CAI15821.1 xref: EMBL:CAI15822.1 xref: EMBL:CAI15823.1 xref: EMBL:CAI16366.1 xref: EMBL:CAI16367.1 xref: UniProtKB:Q5VYX4 xref: UniProtKB:Q5VYX5 xref: UniProtKB:Q5VYX6 xref: UniProtKB:Q6ZS13 xref: UniProtKB:Q8N3C2 xref: UniProtKB:Q8N948 xref: UniProtKB:Q9Y6X6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005145 ! MYO16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006472 ! kiaa0578-kiaa0865 physical interaction relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0031342 ! MYO16_HUMAN-Phosphotyrosine1432 [Term] id: CCO:B0005170 name: TRAF2_HUMAN def: "TNF receptor-associated factor 2" [UniProtKB:Q12933] synonym: "Tumor necrosis factor type 2 receptor-associated protein 3" EXACT [UniProtKB:Q12933] xref: EMBL:AAA87706.1 xref: EMBL:AAH32410.1 xref: EMBL:AAH33810.1 xref: EMBL:AAH43492.1 xref: EMBL:AAH64662.1 xref: EMBL:AAT27320.1 xref: EMBL:BAB70792.1 xref: UniProtKB:Q12933 xref: UniProtKB:Q96NT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005823 ! TRAF2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005721 ! cdca3-traf2 physical interaction relationship: participates_in CCO:I0005737 ! pin1-traf2 physical interaction relationship: participates_in CCO:I0005812 ! appl1-traf2 physical interaction relationship: participates_in CCO:I0005828 ! dlg7-traf2 physical interaction relationship: participates_in CCO:I0005878 ! lzts2-traf2 physical interaction relationship: participates_in CCO:I0005898 ! cdkn1b-traf2 physical interaction relationship: participates_in CCO:I0006417 ! traf2-ruvbl1 physical interaction relationship: participates_in CCO:I0006418 ! traf2-frap1 physical interaction relationship: participates_in CCO:I0006858 ! tnf-tnfrsf1a-2 physical interaction relationship: participates_in CCO:I0006859 ! tnf-tnfrsf1a-3 physical interaction relationship: participates_in CCO:I0006860 ! tnf-tnfrsf1a-4 physical interaction relationship: participates_in CCO:I0014954 ! kiaa1838-traf2 physical interaction relationship: participates_in CCO:I0014955 ! traf2-zbtb25 physical interaction relationship: participates_in CCO:I0014964 ! fbxo28-traf2 physical interaction relationship: participates_in CCO:I0015040 ! necap2-traf2 physical interaction relationship: participates_in CCO:I0015041 ! rfx3-traf2 physical interaction relationship: participates_in CCO:I0015070 ! apex2-traf2 physical interaction relationship: participates_in CCO:I0015087 ! tceb3b-traf2 physical interaction relationship: participates_in CCO:I0015092 ! spata2-traf2 physical interaction relationship: participates_in CCO:I0015128 ! c16orf48-traf2 physical interaction relationship: participates_in CCO:I0015130 ! spg21-traf2 physical interaction relationship: participates_in CCO:I0015141 ! c6orf4-traf2 physical interaction relationship: participates_in CCO:I0015144 ! nif3l1-traf2 physical interaction relationship: participates_in CCO:I0015159 ! sox30-traf2 physical interaction relationship: participates_in CCO:I0015171 ! lnx-traf2 physical interaction relationship: participates_in CCO:I0015182 ! aff4-traf2 physical interaction relationship: participates_in CCO:I0015192 ! traf2-znf646 physical interaction relationship: participates_in CCO:I0015197 ! ablim1-traf2 physical interaction relationship: participates_in CCO:I0015245 ! dtnb-traf2 physical interaction relationship: participates_in CCO:I0015257 ! qars-traf2 physical interaction relationship: participates_in CCO:I0015268 ! aasdhppt-traf2 physical interaction relationship: participates_in CCO:I0015289 ! thap7-traf2 physical interaction relationship: participates_in CCO:I0015322 ! traf2-znf297b physical interaction relationship: participates_in CCO:I0015333 ! spry2-traf2 physical interaction relationship: participates_in CCO:I0015337 ! gorasp2-traf2 physical interaction relationship: participates_in CCO:I0015345 ! traf2-traf6 physical interaction relationship: participates_in CCO:I0015350 ! traf2-trim31 physical interaction relationship: participates_in CCO:I0015372 ! ribc2-traf2 physical interaction relationship: participates_in CCO:I0015428 ! chmp2b-traf2 physical interaction relationship: participates_in CCO:I0015440 ! ipo11-traf2 physical interaction relationship: participates_in CCO:I0015462 ! mizf-traf2 physical interaction relationship: participates_in CCO:I0015464 ! traf2-usp2 physical interaction relationship: participates_in CCO:I0015482 ! fate1-traf2 physical interaction relationship: participates_in CCO:I0015484 ! q8n2x6-traf2 physical interaction relationship: participates_in CCO:I0015486 ! bahd1-traf2 physical interaction relationship: participates_in CCO:I0015565 ! dvl2-traf2 physical interaction relationship: participates_in CCO:I0015619 ! rgs14-traf2 physical interaction relationship: participates_in CCO:I0015622 ! cry1-traf2 physical interaction relationship: participates_in CCO:I0015625 ! mgc12538-traf2 physical interaction relationship: participates_in CCO:I0015629 ! ndp52-traf2 physical interaction relationship: participates_in CCO:I0015637 ! birc2-traf2 physical interaction relationship: participates_in CCO:I0015669 ! nrip1-traf2 physical interaction relationship: participates_in CCO:I0015711 ! irf4-traf2 physical interaction relationship: participates_in CCO:I0015718 ! drr1-traf2 physical interaction relationship: participates_in CCO:I0015748 ! tcea2-traf2 physical interaction relationship: participates_in CCO:I0015786 ! rad23a-traf2 physical interaction relationship: participates_in CCO:I0015820 ! tifa-traf2 physical interaction relationship: participates_in CCO:I0015842 ! traf2-traf2-4 physical interaction relationship: participates_in CCO:I0015925 ! atar-traf2-9 physical interaction relationship: participates_in CCO:I0015927 ! rank-traf2 physical interaction relationship: participates_in CCO:I0015983 ! birc2-traf2-5 physical interaction relationship: participates_in CCO:I0016173 ! atxn1-traf2 physical interaction relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0016253 ! tradd-traf2-2 physical interaction relationship: participates_in CCO:I0016477 ! ikbke-traf2 physical interaction relationship: participates_in CCO:I0017111 ! traf2-bag2 physical interaction relationship: participates_in CCO:I0017112 ! traf2-hspa1l physical interaction relationship: participates_in CCO:I0017113 ! traf2-hspa4 physical interaction relationship: participates_in CCO:I0017114 ! traf2-hspa5 physical interaction relationship: participates_in CCO:I0017115 ! traf2-hspa8 physical interaction relationship: participates_in CCO:I0017116 ! traf2-slc25a5 physical interaction relationship: participates_in CCO:I0017117 ! traf2-hspa9b physical interaction relationship: participates_in CCO:I0017118 ! traf2-ruvbl2 physical interaction relationship: participates_in CCO:I0017119 ! traf2-rpl23 physical interaction relationship: participates_in CCO:I0017120 ! traf2-dnaja1 physical interaction relationship: participates_in CCO:I0017121 ! traf2-eef1a2 physical interaction relationship: participates_in CCO:I0017122 ! traf2-cad physical interaction relationship: participates_in CCO:I0017123 ! traf2-actg1 physical interaction relationship: participates_in CCO:I0017124 ! traf2-nap1l1 physical interaction relationship: participates_in CCO:I0017125 ! traf2-cltc physical interaction relationship: participates_in CCO:I0017126 ! traf2-traf2 physical interaction relationship: participates_in CCO:I0017127 ! traf2-hsp70_1 physical interaction relationship: participates_in CCO:I0017128 ! traf2-q96gx9 physical interaction relationship: participates_in CCO:I0017129 ! traf2-adprt physical interaction relationship: participates_in CCO:I0017130 ! traf2-hspca physical interaction relationship: participates_in CCO:I0017131 ! traf2-tuba2 physical interaction relationship: participates_in CCO:I0017132 ! traf2-mylk2 physical interaction relationship: participates_in CCO:I0017202 ! traf1-traf2 physical interaction relationship: participates_in CCO:I0017223 ! tank-traf2 physical interaction relationship: participates_in CCO:I0017255 ! map3k7ip1-traf2 physical interaction relationship: participates_in CCO:I0017261 ! tbk1-traf2 physical interaction relationship: participates_in CCO:I0017262 ! tnfrsf1b-traf2 physical interaction relationship: participates_in CCO:I0017263 ! tradd-traf2 physical interaction relationship: participates_in CCO:I0017414 ! gstp1-traf2-2 physical interaction relationship: participates_in CCO:I0017415 ! gstp1-traf2-4 physical interaction relationship: participates_in CCO:I0017416 ! traf2-ask1 physical interaction relationship: participates_in CCO:I0017417 ! traf2-mekk1 physical interaction relationship: participates_in CCO:I0017505 ! traf1-traf2-1 physical interaction relationship: participates_in CCO:I0017506 ! traf2-traf1 physical interaction relationship: participates_in CCO:I0017507 ! traf2-traf2-2 physical interaction relationship: participates_in CCO:I0017509 ! tnfr2-traf2-2 physical interaction relationship: participates_in CCO:I0017609 ! atxn1-traf2-1 physical interaction relationship: participates_in CCO:I0017682 ! tnfr2-traf2 physical interaction relationship: participates_in CCO:I0017785 ! tradd-traf2-3 direct interaction relationship: participates_in CCO:I0018044 ! cd27-traf2-1 physical interaction relationship: participates_in CCO:I0018247 ! gstp1-traf2 physical interaction relationship: participates_in CCO:I0018314 ! tnf_r1-tradd-1 physical interaction relationship: participates_in CCO:I0018376 ! birc2-traf2-1 physical interaction relationship: participates_in CCO:I0018379 ! birc2-traf2-4 physical interaction relationship: participates_in CCO:I0018552 ! birc2-traf2-2 physical interaction relationship: participates_in CCO:I0018553 ! birc3-traf2-1 physical interaction relationship: participates_in CCO:I0018554 ! birc3-traf2-3 physical interaction relationship: participates_in CCO:I0018797 ! tnf_r1-tradd physical interaction relationship: participates_in CCO:I0018883 ! gstp1-traf2-3 physical interaction relationship: participates_in CCO:I0018899 ! ubqln4-traf2 physical interaction relationship: participates_in CCO:I0019301 ! birc2-traf2-3 physical interaction relationship: participates_in CCO:I0019302 ! birc3-traf2-2 physical interaction relationship: participates_in CCO:I0019368 ! taj-traf2 physical interaction relationship: participates_in CCO:I0019496 ! cd27-traf2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation [Term] id: CCO:B0005171 name: RBTN2_HUMAN def: "Rhombotin-2" [UniProtKB:P25791] synonym: "Cysteine-rich protein TTG-2" EXACT [UniProtKB:P25791] synonym: "LIM domain only protein 2" EXACT [UniProtKB:P25791] synonym: "T-cell translocation protein 2" EXACT [UniProtKB:P25791] xref: EMBL:AAF98804.1 xref: EMBL:AAH34041.1 xref: EMBL:AAH35607.1 xref: EMBL:AAH42426.1 xref: EMBL:AAH73973.1 xref: EMBL:CAA43430.1 xref: UniProtKB:P25791 xref: UniProtKB:Q9HD58 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005452 ! LMO2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005722 ! lmo2-mapre2 physical interaction relationship: participates_in CCO:I0005762 ! lmo2-stat1 physical interaction relationship: participates_in CCO:I0005822 ! lmo2-mapre3 physical interaction [Term] id: CCO:B0005172 name: Q96AQ3_HUMAN def: "ATF4 protein" [UniProtKB:Q96AQ3] synonym: "Activating transcription factor 4 (Tax-responsive enhancer element B67)" EXACT [UniProtKB:Q96AQ3] synonym: "Activating transcription factor 4 (Tax-responsive enhancer element B67), isoform CRA_a" EXACT [UniProtKB:Q96AQ3] xref: EMBL:AAH16855.1 xref: EMBL:AAH22088.1 xref: EMBL:AAH44895.1 xref: EMBL:AAH73754.1 xref: EMBL:CAG30270.1 xref: EMBL:EAW60341.1 xref: UniProtKB:Q96AQ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006035 ! ATF4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005723 ! atf4-gps2 physical interaction relationship: participates_in CCO:I0015153 ! atf4-ldoc1 physical interaction [Term] id: CCO:B0005173 name: KPCI_HUMAN def: "Protein kinase C iota type" [UniProtKB:P41743] synonym: "aPKC-lambda/iota" EXACT [UniProtKB:P41743] synonym: "Atypical protein kinase C-lambda/iota" EXACT [UniProtKB:P41743] synonym: "EC 2.7.11.13" EXACT [UniProtKB:P41743] synonym: "nPKC-iota" EXACT [UniProtKB:P41743] synonym: "PRKC-lambda/iota" EXACT [UniProtKB:P41743] xref: EMBL:AAA60171.1 xref: EMBL:AAB17011.1 xref: EMBL:AAH22016.3 xref: UniProtKB:P41743 xref: UniProtKB:Q8WW06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004958 ! PRKCI_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005724 ! pard6a-prkci physical interaction relationship: participates_in CCO:I0005988 ! pard6a-prkci-1 physical interaction relationship: participates_in CCO:I0005990 ! pard6b-prkci-1 physical interaction relationship: participates_in CCO:I0005992 ! pard6g-prkci-1 physical interaction relationship: participates_in CCO:I0006238 ! pard6a-prkci-3 direct interaction relationship: participates_in CCO:I0006467 ! prcki-pard6-1 physical interaction relationship: participates_in CCO:I0006830 ! prkci-pard6b-1 physical interaction relationship: participates_in CCO:I0006838 ! pard6b-rac1-2 physical interaction relationship: participates_in CCO:I0006839 ! pard6b-cdc42-5 physical interaction relationship: participates_in CCO:I0007062 ! pard6b-prkci-2 physical interaction relationship: participates_in CCO:I0007063 ! rac1-pard6b-2 physical interaction relationship: participates_in CCO:I0007064 ! cdc42-pard6b-2 physical interaction relationship: participates_in CCO:I0007203 ! pard6a-prkci-2 physical interaction relationship: participates_in CCO:I0007206 ! prkci-pard6a-1 physical interaction relationship: participates_in CCO:I0007207 ! prkci-pard6b-2 physical interaction relationship: participates_in CCO:I0007211 ! prkci-pard3-1 physical interaction relationship: participates_in CCO:I0007221 ! pard3-prkci-2 physical interaction relationship: participates_in CCO:I0007229 ! pard6b-prkci-3 physical interaction relationship: participates_in CCO:I0007520 ! pard6a-prcki-1 physical interaction relationship: participates_in CCO:I0007521 ! prcki-pard6a-1 physical interaction relationship: participates_in CCO:I0015886 ! prcki-rac1-1 physical interaction relationship: participates_in CCO:I0015887 ! prkci-cdc42-1 physical interaction relationship: participates_in CCO:I0018276 ! ywhah-prkci-1 physical interaction relationship: participates_in CCO:I0018277 ! prkci-mark4-1 physical interaction relationship: participates_in CCO:I0018278 ! prkci-par5-1 physical interaction relationship: participates_in CCO:I0018284 ! pnma1-prcki-1 physical interaction relationship: participates_in CCO:I0018288 ! ywhaz-prkci-1 physical interaction relationship: participates_in CCO:I0018292 ! prkci-cdc42-2 physical interaction relationship: participates_in CCO:I0018293 ! cdc42-prkci-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0012629 ! KPCI_HUMAN-Phosphotyrosine256 relationship: transforms_into CCO:B0012630 ! KPCI_HUMAN-Phosphotyrosine271 relationship: transforms_into CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: transforms_into CCO:B0012632 ! KPCI_HUMAN-Phosphothreonine403 relationship: transforms_into CCO:B0012633 ! KPCI_HUMAN-Phosphothreonine555 [Term] id: CCO:B0005174 name: NADC_HUMAN def: "Nicotinate-nucleotide pyrophosphorylase [carboxylating]" [UniProtKB:Q15274] synonym: "EC 2.4.2.19" EXACT [UniProtKB:Q15274] synonym: "QAPRTase" EXACT [UniProtKB:Q15274] synonym: "QPRTase" EXACT [UniProtKB:Q15274] synonym: "Quinolinate phosphoribosyltransferase [decarboxylating]" EXACT [UniProtKB:Q15274] xref: EMBL:AAH05060.1 xref: EMBL:AAH10033.1 xref: EMBL:AAH18910.1 xref: EMBL:AAP35895.1 xref: EMBL:BAA11242.1 xref: UniProtKB:Q15274 xref: UniProtKB:Q53XW7 xref: UniProtKB:Q96G22 xref: UniProtKB:Q9BSG6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005155 ! QPRT_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000911 ! nicotinate-nucleotide diphosphorylase (carboxylating) activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005726 ! qprt-sufu physical interaction [Term] id: CCO:B0005175 name: BAD_HUMAN def: "Bcl2 antagonist of cell death" [UniProtKB:Q92934] synonym: "BAD" EXACT [UniProtKB:Q92934] synonym: "Bcl-2-binding component 6" EXACT [UniProtKB:Q92934] synonym: "Bcl-2-like 8 protein" EXACT [UniProtKB:Q92934] synonym: "Bcl-XL/Bcl-2-associated death promoter" EXACT [UniProtKB:Q92934] xref: EMBL:AAB36516.1 xref: EMBL:AAB72092.1 xref: EMBL:AAB88124.1 xref: EMBL:AAH01901.1 xref: EMBL:AAP35324.1 xref: UniProtKB:O14803 xref: UniProtKB:Q92934 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004134 ! BAD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005727 ! bad-sfn physical interaction relationship: participates_in CCO:I0006209 ! bcl2-bad-1 physical interaction relationship: participates_in CCO:I0007443 ! bad-bcl2-1 physical interaction relationship: participates_in CCO:I0007444 ! bad-bcl2-2 physical interaction relationship: participates_in CCO:I0007767 ! bad-bcl2-3 direct interaction relationship: participates_in CCO:I0007881 ! bad_bcl2_human direct interaction relationship: participates_in CCO:I0015543 ! bad-ewsr1 physical interaction relationship: participates_in CCO:I0018081 ! bnip3alpha-bcl_xl-1 direct interaction relationship: participates_in CCO:I0018082 ! bnip3alpha-bcl_xl-2 direct interaction relationship: participates_in CCO:I0019272 ! bad-bclw-1 direct interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: transforms_into CCO:B0010725 ! BAD_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0010726 ! BAD_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0010727 ! BAD_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0010728 ! BAD_HUMAN-Phosphoserine134 [Term] id: CCO:B0005176 name: T22D4_HUMAN def: "TSC22 domain family protein 4" [UniProtKB:Q9Y3Q8] synonym: "Tsc-22-like protein THG-1" EXACT [UniProtKB:Q9Y3Q8] synonym: "TSC22-related-inducible leucine zipper protein 2" EXACT [UniProtKB:Q9Y3Q8] xref: EMBL:AAH01486.1 xref: EMBL:AAH01966.1 xref: EMBL:AAH02972.1 xref: EMBL:AAH10406.1 xref: EMBL:CAB43491.1 xref: UniProtKB:Q9Y3Q8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005715 ! TSC22D4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005728 ! ccnk-tsc22d4 physical interaction relationship: participates_in CCO:I0005745 ! pin1-tsc22d4 physical interaction relationship: participates_in CCO:I0005786 ! cdk5r1-tsc22d4 physical interaction relationship: participates_in CCO:I0005802 ! mad2l1-tsc22d4 physical interaction relationship: participates_in CCO:I0005848 ! cdc23-tsc22d4 physical interaction relationship: participates_in CCO:I0005867 ! cks2-tsc22d4 physical interaction relationship: participates_in CCO:I0008680 ! psma1-tsc22d4 physical interaction relationship: participates_in CCO:I0014951 ! gorasp2-tsc22d4 physical interaction relationship: participates_in CCO:I0015067 ! frmd6-tsc22d4 physical interaction relationship: participates_in CCO:I0015096 ! c16orf48-tsc22d4 physical interaction relationship: participates_in CCO:I0015219 ! tex11-tsc22d4 physical interaction relationship: participates_in CCO:I0015237 ! tsc22d4-znf580 physical interaction relationship: participates_in CCO:I0015241 ! sat-tsc22d4 physical interaction relationship: participates_in CCO:I0015302 ! tsc22d4-zmynd10 physical interaction relationship: participates_in CCO:I0015496 ! ablim1-tsc22d4 physical interaction relationship: participates_in CCO:I0015519 ! bcon3-tsc22d4 physical interaction relationship: participates_in CCO:I0015523 ! lnx-tsc22d4 physical interaction relationship: participates_in CCO:I0015614 ! mgc3162-tsc22d4 physical interaction relationship: participates_in CCO:I0015657 ! syt17-tsc22d4 physical interaction relationship: participates_in CCO:I0015695 ! nif3l1-tsc22d4 physical interaction relationship: participates_in CCO:I0015704 ! tsc22d4-ublcp1 physical interaction relationship: participates_in CCO:I0015781 ! mthfs-tsc22d4 physical interaction relationship: participates_in CCO:I0015787 ! gnb2l1-tsc22d4 physical interaction relationship: participates_in CCO:I0016160 ! pdcd8-tsc22d4 physical interaction relationship: participates_in CCO:I0016188 ! pcbp1-tsc22d4 physical interaction relationship: participates_in CCO:I0017547 ! tsc22d4-pdcd8 physical interaction relationship: participates_in CCO:I0017581 ! tsc22d4-prnp physical interaction relationship: participates_in CCO:I0017585 ! tsc22d4-sacs physical interaction relationship: participates_in CCO:I0019151 ! pcbp1-tsc22d4-1 physical interaction relationship: participates_in CCO:I0019414 ! zmynd10-tsc22d4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0041201 ! T22D4_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0041202 ! T22D4_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0041203 ! T22D4_HUMAN-Phosphothreonine211 relationship: transforms_into CCO:B0041204 ! T22D4_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0071066 ! T22D4_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0071067 ! T22D4_HUMAN-Phosphothreonine229 relationship: transforms_into CCO:B0071068 ! T22D4_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0071069 ! T22D4_HUMAN-Phosphoserine370 [Term] id: CCO:B0005177 name: DCTN2_HUMAN def: "Dynactin subunit 2" [UniProtKB:Q13561] synonym: "50 kDa dynein-associated polypeptide" EXACT [UniProtKB:Q13561] synonym: "DCTN-50" EXACT [UniProtKB:Q13561] synonym: "Dynactin complex 50 kDa subunit" EXACT [UniProtKB:Q13561] synonym: "p50 dynamitin" EXACT [UniProtKB:Q13561] xref: EMBL:AAC50423.1 xref: EMBL:AAH00718.1 xref: EMBL:AAH09468.1 xref: EMBL:AAH14083.1 xref: EMBL:AAO34395.1 xref: UniProtKB:Q13561 xref: UniProtKB:Q86YN2 xref: UniProtKB:Q9BW17 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004448 ! DCTN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005729 ! dctn2-gadd45a physical interaction relationship: participates_in CCO:I0019965 ! dctn2-gnao1 physical interaction relationship: transforms_into CCO:B0011453 ! DCTN2_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0031310 ! DCTN2_HUMAN-Phosphotyrosine86 [Term] id: CCO:B0005178 name: RBPMS_HUMAN def: "RNA-binding protein with multiple splicing" [UniProtKB:Q93062] synonym: "RBP-MS" EXACT [UniProtKB:Q93062] xref: EMBL:AAH03608.1 xref: EMBL:BAA12225.1 xref: EMBL:BAA12226.1 xref: EMBL:BAA12227.1 xref: EMBL:BAA12228.1 xref: EMBL:BAA12229.1 xref: UniProtKB:Q92516 xref: UniProtKB:Q92517 xref: UniProtKB:Q92518 xref: UniProtKB:Q93062 xref: UniProtKB:Q96J26 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005451 ! RBPMS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005730 ! lzts2-rbpms physical interaction relationship: participates_in CCO:I0005798 ! ccnk-rbpms physical interaction relationship: participates_in CCO:I0005806 ! cdc23-rbpms physical interaction relationship: participates_in CCO:I0005881 ! pin1-rbpms physical interaction relationship: participates_in CCO:I0014967 ! dtx2-rbpms physical interaction relationship: participates_in CCO:I0014969 ! rbpms-tollip physical interaction relationship: participates_in CCO:I0015001 ! fkhl18-rbpms physical interaction relationship: participates_in CCO:I0015056 ! pepp2-rbpms physical interaction relationship: participates_in CCO:I0015101 ! cdc42ep1-rbpms physical interaction relationship: participates_in CCO:I0015187 ! grap2-rbpms physical interaction relationship: participates_in CCO:I0015252 ! c9orf100-rbpms physical interaction relationship: participates_in CCO:I0015260 ! ewsr1-rbpms physical interaction relationship: participates_in CCO:I0015293 ! rbpms-znf581 physical interaction relationship: participates_in CCO:I0015374 ! hoxa9-rbpms physical interaction relationship: participates_in CCO:I0015403 ! pitx1-rbpms physical interaction relationship: participates_in CCO:I0015451 ! rbpms-sf1 physical interaction relationship: participates_in CCO:I0015574 ! eya2-rbpms physical interaction relationship: participates_in CCO:I0015576 ! arhgap9-rbpms physical interaction relationship: participates_in CCO:I0015599 ! dvl2-rbpms physical interaction relationship: participates_in CCO:I0015641 ! rbm9-rbpms physical interaction relationship: participates_in CCO:I0015653 ! hoxb9-rbpms physical interaction relationship: participates_in CCO:I0015683 ! heyl-rbpms physical interaction relationship: participates_in CCO:I0015772 ! otx1-rbpms physical interaction relationship: participates_in CCO:I0016171 ! atxn1-rbpms physical interaction relationship: participates_in CCO:I0016189 ! atxn1-rbpms-2 physical interaction relationship: participates_in CCO:I0017607 ! atxn1-rbpms-1 physical interaction relationship: transforms_into CCO:B0069832 ! RBPMS_HUMAN-Phosphothreonine113 relationship: transforms_into CCO:B0069833 ! RBPMS_HUMAN-Phosphothreonine118 [Term] id: CCO:B0005179 name: CH032_HUMAN def: "Uncharacterized protein C8orf32" [UniProtKB:Q96HA8] xref: EMBL:AAH08781.1 xref: EMBL:BAA91488.1 xref: UniProtKB:Q96HA8 xref: UniProtKB:Q9NW95 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004341 ! C8orf32_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005731 ! c8orf32-nme1 physical interaction relationship: participates_in CCO:I0005814 ! c8orf32-sfn physical interaction relationship: participates_in CCO:I0015064 ! birc4-c8orf32 physical interaction relationship: participates_in CCO:I0015371 ! c8orf32-mdfi physical interaction relationship: participates_in CCO:I0015396 ! c8orf32-hprt1 physical interaction relationship: participates_in CCO:I0015435 ! c8orf32-cbfa2t2 physical interaction relationship: participates_in CCO:I0015785 ! c8orf32-pcbd1 physical interaction [Term] id: CCO:B0005180 name: DAZP2_HUMAN def: "DAZ-associated protein 2" [UniProtKB:Q15038] synonym: "Deleted in azoospermia-associated protein 2" EXACT [UniProtKB:Q15038] xref: EMBL:AAH02334.1 xref: EMBL:AAH07900.1 xref: EMBL:AAR11454.1 xref: EMBL:BAA06545.2 xref: UniProtKB:Q15038 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004439 ! DAZAP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005732 ! dazap2-sept2 physical interaction relationship: participates_in CCO:I0015106 ! dazap2-poli physical interaction relationship: participates_in CCO:I0015236 ! dazap2-znf581 physical interaction relationship: participates_in CCO:I0015261 ! aatf-dazap2 physical interaction relationship: participates_in CCO:I0015314 ! dazap2-tollip physical interaction relationship: participates_in CCO:I0015420 ! dazap2-rbm9 physical interaction relationship: participates_in CCO:I0015534 ! dazap2-pepp2 physical interaction relationship: participates_in CCO:I0015551 ! dazap2-hgs physical interaction relationship: participates_in CCO:I0015660 ! bag3-dazap2 physical interaction relationship: participates_in CCO:I0015762 ! dazap2-wwp1 physical interaction relationship: participates_in CCO:I0016164 ! atxn1-dazap2 physical interaction relationship: participates_in CCO:I0017602 ! atxn1-dazap2-1 physical interaction relationship: participates_in CCO:I0020535 ! dazap2-tle1 physical interaction [Term] id: CCO:B0005181 name: UBQL1_HUMAN def: "Ubiquilin-1" [UniProtKB:Q9UMX0] synonym: "hPLIC-1" EXACT [UniProtKB:Q9UMX0] synonym: "PLIC-1" EXACT [UniProtKB:Q9UMX0] synonym: "Protein linking IAP with cytoskeleton 1" EXACT [UniProtKB:Q9UMX0] xref: EMBL:AAD49751.3 xref: EMBL:AAG02473.1 xref: EMBL:AAH10066.1 xref: EMBL:AAH39294.1 xref: EMBL:BAB20436.1 xref: EMBL:BAC11045.1 xref: EMBL:CAB66578.1 xref: UniProtKB:Q8IXS9 xref: UniProtKB:Q8N2Q3 xref: UniProtKB:Q9H0T8 xref: UniProtKB:Q9H3R4 xref: UniProtKB:Q9HAZ5 xref: UniProtKB:Q9UMX0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005872 ! UBQLN1_human relationship: has_function CCO:F0004209 ! kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0005789 ! hrasls3-ubqln1 physical interaction relationship: participates_in CCO:I0015117 ! gabrd-ubqln1 physical interaction relationship: participates_in CCO:I0015291 ! fzd7-ubqln1 physical interaction relationship: participates_in CCO:I0015737 ! hgs-ubqln1 physical interaction [Term] id: CCO:B0005183 name: PLDN_HUMAN def: "Pallidin" [UniProtKB:Q9UL45] synonym: "Pallid protein homolog" EXACT [UniProtKB:Q9UL45] synonym: "Syntaxin 13-interacting protein" EXACT [UniProtKB:Q9UL45] xref: EMBL:AAF08343.1 xref: EMBL:AAH04819.1 xref: UniProtKB:Q9UL45 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005335 ! PLDN_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004403 ! syntaxin-13 binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005739 ! c18orf24-pldn physical interaction relationship: participates_in CCO:I0005764 ! kntc2-pldn physical interaction relationship: participates_in CCO:I0015017 ! eps8-pldn physical interaction relationship: participates_in CCO:I0015509 ! aggf1-pldn physical interaction [Term] id: CCO:B0005184 name: CS050_HUMAN def: "UPF0459 protein C19orf50" [UniProtKB:Q9BQD3] xref: EMBL:AAC25583.1 xref: EMBL:AAH01080.1 xref: EMBL:AAH06479.1 xref: UniProtKB:O76098 xref: UniProtKB:Q9BQD3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004401 ! C19orf50_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015016 ! ewsr1-mgc2749 physical interaction relationship: participates_in CCO:I0015157 ! mgc2749-tceb3b physical interaction relationship: participates_in CCO:I0015183 ! ing5-mgc2749 physical interaction relationship: participates_in CCO:I0015402 ! mgc2749-zbtb25 physical interaction relationship: participates_in CCO:I0015414 ! lmo3-mgc2749 physical interaction relationship: participates_in CCO:I0015674 ! mgc2749-nif3l1 physical interaction [Term] id: CCO:B0005185 name: MAGBI_HUMAN def: "Melanoma-associated antigen B18" [UniProtKB:Q96M61] synonym: "MAGE-B18 antigen" EXACT [UniProtKB:Q96M61] xref: EMBL:AAH29525.1 xref: EMBL:BAB71450.1 xref: UniProtKB:Q96M61 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005018 ! MAGEB18_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005741 ! mageb18-tp53 physical interaction relationship: participates_in CCO:I0006656 ! mageb18-tp53-1 physical interaction relationship: participates_in CCO:I0015579 ! gabpb2-mageb18 physical interaction [Term] id: CCO:B0005186 name: CR025_HUMAN def: "Uncharacterized protein C18orf25" [UniProtKB:Q96B23] xref: EMBL:AAH16149.1 xref: EMBL:AAH84579.1 xref: EMBL:BAF82427.1 xref: EMBL:BAF85670.1 xref: EMBL:CAD28470.1 xref: EMBL:CAD89920.1 xref: EMBL:CAE45812.1 xref: EMBL:EAX01473.1 xref: UniProtKB:A8K123 xref: UniProtKB:A8KAB6 xref: UniProtKB:Q5XG78 xref: UniProtKB:Q6N058 xref: UniProtKB:Q86TB5 xref: UniProtKB:Q8TCQ5 xref: UniProtKB:Q96B23 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004392 ! C18orf25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005742 ! c18orf25-ube2i physical interaction relationship: transforms_into CCO:B0011339 ! CR025_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0011340 ! CR025_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0011341 ! CR025_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0011342 ! CR025_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0064458 ! CR025_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0064459 ! CR025_HUMAN-Phosphoserine329 [Term] id: CCO:B0005187 name: TEX11_HUMAN def: "Testis-expressed sequence 11 protein" [UniProtKB:Q8IYF3] xref: EMBL:AAH36016.2 xref: EMBL:AAK31973.1 xref: EMBL:BAB71465.1 xref: EMBL:BAB71520.1 xref: EMBL:CAI39957.1 xref: EMBL:CAI39958.1 xref: EMBL:CAI40155.1 xref: EMBL:CAI41495.1 xref: EMBL:CAI41496.1 xref: UniProtKB:Q5JQQ8 xref: UniProtKB:Q8IYF3 xref: UniProtKB:Q96LZ4 xref: UniProtKB:Q96M47 xref: UniProtKB:Q9BXU6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005762 ! TEX11_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005743 ! mad1l1-tex11 physical interaction relationship: participates_in CCO:I0005769 ! cdkn1a-tex11 physical interaction relationship: participates_in CCO:I0005868 ! dusp6-tex11 physical interaction relationship: participates_in CCO:I0015109 ! tex11-znf414 physical interaction relationship: participates_in CCO:I0015219 ! tex11-tsc22d4 physical interaction relationship: participates_in CCO:I0015391 ! nrip1-tex11 physical interaction relationship: participates_in CCO:I0015406 ! stmn2-tex11 physical interaction relationship: participates_in CCO:I0019422 ! stmn2-tex11-1 physical interaction [Term] id: CCO:B0005189 name: Q9BVR6_HUMAN def: "TUBGCP4 protein" [UniProtKB:Q9BVR6] xref: EMBL:AAH00966.1 xref: UniProtKB:Q9BVR6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006046 ! TUBGCP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005746 ! krt18-q9bvr6 physical interaction relationship: participates_in CCO:I0005927 ! mad1l1-q9bvr6 physical interaction [Term] id: CCO:B0005191 name: SATB1_HUMAN def: "DNA-binding protein SATB1" [UniProtKB:Q01826] synonym: "Special AT-rich sequence-binding protein 1" EXACT [UniProtKB:Q01826] xref: EMBL:AAA60304.1 xref: EMBL:AAH01744.1 xref: UniProtKB:Q01826 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005567 ! SATB1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000310 ! nuclear heterochromatin relationship: participates_in CCO:I0005748 ! satb1-ube2i physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005192 name: RAI1_HUMAN def: "Retinoic acid-induced protein 1" [UniProtKB:Q7Z5J4] xref: EMBL:AAH21209.1 xref: EMBL:AAO31738.1 xref: EMBL:BAB47449.1 xref: EMBL:CAB63768.1 xref: EMBL:CAC20423.1 xref: EMBL:CAC20424.1 xref: EMBL:CAD39127.1 xref: EMBL:CAD39144.1 xref: UniProtKB:Q7Z5J4 xref: UniProtKB:Q8N3B4 xref: UniProtKB:Q8ND08 xref: UniProtKB:Q8WU64 xref: UniProtKB:Q96JK5 xref: UniProtKB:Q9H1C1 xref: UniProtKB:Q9H1C2 xref: UniProtKB:Q9UF69 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005422 ! RAI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005749 ! pin1-rai1 physical interaction relationship: transforms_into CCO:B0013688 ! RAI1_HUMAN-Phosphoserine568 relationship: transforms_into CCO:B0013689 ! RAI1_HUMAN-Phosphoserine571 relationship: transforms_into CCO:B0013690 ! RAI1_HUMAN-Phosphoserine574 relationship: transforms_into CCO:B0013691 ! RAI1_HUMAN-Phosphothreonine1476 relationship: transforms_into CCO:B0048367 ! RAI1_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0069707 ! RAI1_HUMAN-Phosphoserine683 relationship: transforms_into CCO:B0069708 ! RAI1_HUMAN-Phosphothreonine696 relationship: transforms_into CCO:B0069709 ! RAI1_HUMAN-Phosphoserine880 relationship: transforms_into CCO:B0069710 ! RAI1_HUMAN-Phosphoserine892 relationship: transforms_into CCO:B0069711 ! RAI1_HUMAN-Phosphoserine1108 relationship: transforms_into CCO:B0069712 ! RAI1_HUMAN-Phosphoserine1122 relationship: transforms_into CCO:B0069713 ! RAI1_HUMAN-Phosphoserine1352 relationship: transforms_into CCO:B0069714 ! RAI1_HUMAN-Phosphoserine1358 relationship: transforms_into CCO:B0069715 ! RAI1_HUMAN-Phosphoserine1374 relationship: transforms_into CCO:B0069716 ! RAI1_HUMAN-Phosphoserine1431 [Term] id: CCO:B0005193 name: Q8TB93_HUMAN def: "p21 protein (Cdc42/Rac)-activated kinase 7" [UniProtKB:Q8TB93] xref: EMBL:AAH24179.1 xref: UniProtKB:Q8TB93 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006030 ! PAK7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005750 ! lzts2-pak7 physical interaction [Term] id: CCO:B0005194 name: PKHF2_HUMAN def: "Pleckstrin homology domain-containing family F member 2" [UniProtKB:Q9H8W4] synonym: "PH and FYVE domain-containing protein 2" EXACT [UniProtKB:Q9H8W4] synonym: "PH domain-containing family F member 2" EXACT [UniProtKB:Q9H8W4] synonym: "Phafin-2" EXACT [UniProtKB:Q9H8W4] synonym: "Zinc finger FYVE domain-containing protein 18" EXACT [UniProtKB:Q9H8W4] xref: EMBL:AAH11806.1 xref: EMBL:AAL30774.1 xref: EMBL:BAB14486.1 xref: EMBL:CAD39132.1 xref: UniProtKB:Q9H8W4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005327 ! PLEKHF2_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000978 ! transport vesicle relationship: participates_in CCO:I0005751 ! plekhf2-sfn physical interaction relationship: participates_in CCO:I0015198 ! plekhf2-rtn4 physical interaction relationship: participates_in CCO:I0015324 ! dkfzp434h142-plekhf2 physical interaction relationship: participates_in CCO:I0015334 ! nono-plekhf2 physical interaction relationship: participates_in CCO:I0015571 ! plekhf2-tsc22d3 physical interaction relationship: participates_in CCO:I0015580 ! mbip-plekhf2 physical interaction relationship: participates_in CCO:I0015598 ! plekhf2-prkar1a physical interaction relationship: participates_in CCO:I0015706 ! plekhf2-znf263 physical interaction relationship: participates_in CCO:I0015779 ! max-plekhf2 physical interaction relationship: transforms_into CCO:B0013546 ! PKHF2_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0069340 ! PKHF2_HUMAN-Phosphoserine248 [Term] id: CCO:B0005195 name: DACH1_HUMAN def: "Dachshund homolog 1" [UniProtKB:Q9UI36] synonym: "Dach1" EXACT [UniProtKB:Q9UI36] xref: EMBL:AAC33466.1 xref: EMBL:AAF01351.1 xref: EMBL:AAH21219.2 xref: EMBL:AAL08487.1 xref: EMBL:CAA06666.1 xref: EMBL:CAB45153.1 xref: EMBL:CAC12840.2 xref: EMBL:CAH73005.1 xref: EMBL:CAH73006.1 xref: EMBL:CAH73303.1 xref: EMBL:CAH73304.1 xref: EMBL:CAI14979.1 xref: EMBL:CAI14980.1 xref: EMBL:CAI16673.1 xref: UniProtKB:O75523 xref: UniProtKB:O75687 xref: UniProtKB:Q5VYY3 xref: UniProtKB:Q5VYY4 xref: UniProtKB:Q96SG3 xref: UniProtKB:Q96SG4 xref: UniProtKB:Q9H524 xref: UniProtKB:Q9UI36 xref: UniProtKB:Q9UMH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004434 ! DACH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005752 ! dach1-ube2i physical interaction relationship: participates_in CCO:I0008979 ! dach- madh3-1 physical interaction relationship: participates_in CCO:I0015272 ! dach1-nagk physical interaction relationship: participates_in CCO:I0017304 ! dach-ncor1-2 physical interaction relationship: participates_in CCO:I0018135 ! dach-madh4-1 physical interaction relationship: participates_in CCO:I0018281 ! dach-sin3a-1 physical interaction relationship: participates_in CCO:I0018282 ! dach-ncor1-1 physical interaction relationship: participates_in CCO:I0018582 ! dach-madh4-2 physical interaction relationship: participates_in CCO:I0018584 ! dach-madh4-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011423 ! DACH1_HUMAN-Phosphothreonine578 relationship: transforms_into CCO:B0011424 ! DACH1_HUMAN-Phosphoserine581 relationship: transforms_into CCO:B0011425 ! DACH1_HUMAN-Phosphothreonine582 relationship: transforms_into CCO:B0011426 ! DACH1_HUMAN-Phosphothreonine584 [Term] id: CCO:B0005196 name: Q8N374_HUMAN def: "MYO15B protein" [UniProtKB:Q8N374] xref: EMBL:AAH27875.1 xref: UniProtKB:Q8N374 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006021 ! MYO15B_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0005753 ! myo15b-sssca1 physical interaction relationship: participates_in CCO:I0005835 ! myo15b-rad54b physical interaction [Term] id: CCO:B0005197 name: AP2B1_HUMAN def: "AP-2 complex subunit beta-1" [UniProtKB:P63010] synonym: "Adapter-related protein complex 2 beta-1 subunit" EXACT [UniProtKB:P63010] synonym: "AP105B" EXACT [UniProtKB:P63010] synonym: "Beta-adaptin" EXACT [UniProtKB:P63010] synonym: "Beta2-adaptin" EXACT [UniProtKB:P63010] synonym: "Clathrin assembly protein complex 2 beta large chain" EXACT [UniProtKB:P63010] synonym: "Plasma membrane adaptor HA2/AP2 adaptin beta subunit" EXACT [UniProtKB:P63010] xref: EMBL:AAA35583.1 xref: EMBL:AAH06201.1 xref: EMBL:EAW80133.1 xref: UniProtKB:A6NJP3 xref: UniProtKB:P21851 xref: UniProtKB:P63010 xref: UniProtKB:Q96J19 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004073 ! AP2B1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: participates_in CCO:I0005754 ! ap2b1-mlh1 physical interaction relationship: participates_in CCO:I0015365 ! ap2b1-ldlrap1 physical interaction relationship: participates_in CCO:I0015562 ! ap2b1-terf2ip physical interaction relationship: transforms_into CCO:B0010564 ! AP2B1_HUMAN-Phosphotyrosine737 relationship: transforms_into CCO:B0031293 ! AP2B1_HUMAN-Phosphotyrosine888 [Term] id: CCO:B0005198 name: NUDC3_HUMAN def: "NudC domain-containing protein 3" [UniProtKB:Q8IVD9] xref: EMBL:AAH03691.1 xref: EMBL:AAH11673.1 xref: EMBL:AAH35014.1 xref: EMBL:AAQ96892.1 xref: EMBL:BAA83020.1 xref: EMBL:BAB14855.1 xref: UniProtKB:Q8IVD9 xref: UniProtKB:Q9BTI3 xref: UniProtKB:Q9H7W9 xref: UniProtKB:Q9UPT4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005222 ! NUDCD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005755 ! nudcd3-ube2i physical interaction relationship: transforms_into CCO:B0013284 ! NUDC3_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0013285 ! NUDC3_HUMAN-Phosphoserine340 [Term] id: CCO:B0005199 name: HPBP1_HUMAN def: "Hsp70-binding protein 1" [UniProtKB:Q9NZL4] synonym: "Heat shock protein-binding protein 1" EXACT [UniProtKB:Q9NZL4] synonym: "Hsp70-binding protein 2" EXACT [UniProtKB:Q9NZL4] synonym: "Hsp70-interacting protein 1" EXACT [UniProtKB:Q9NZL4] synonym: "Hsp70-interacting protein 2" EXACT [UniProtKB:Q9NZL4] synonym: "HspBP1" EXACT [UniProtKB:Q9NZL4] synonym: "HspBP2" EXACT [UniProtKB:Q9NZL4] xref: EMBL:AAC79703.1 xref: EMBL:AAF35833.1 xref: EMBL:AAG17238.1 xref: EMBL:AAH01236.1 xref: EMBL:AAH02373.1 xref: EMBL:BAB18742.1 xref: EMBL:BAC85399.1 xref: EMBL:CAG33399.1 xref: UniProtKB:O95351 xref: UniProtKB:Q6ZNU5 xref: UniProtKB:Q9NZL4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004826 ! HSPBP1_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005756 ! hspa2-hspbp1 physical interaction relationship: participates_in CCO:I0006653 ! hspbp1-hspa2 physical interaction relationship: participates_in CCO:I0006663 ! hspa2-hspbp1-1 physical interaction relationship: participates_in CCO:I0008250 ! hspbp1-rif1 physical interaction relationship: participates_in CCO:I0016632 ! map3k1-q9nzl4 physical interaction relationship: participates_in CCO:I0018256 ! hspa1a-hspbp1-1 direct interaction relationship: transforms_into CCO:B0066892 ! HPBP1_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0066893 ! HPBP1_HUMAN-Phosphoserine359 [Term] id: CCO:B0005200 name: GGA2_HUMAN def: "ADP-ribosylation factor-binding protein GGA2" [UniProtKB:Q9UJY4] synonym: "Gamma-adaptin-related protein 2" EXACT [UniProtKB:Q9UJY4] synonym: "Golgi-localized, gamma ear-containing, ARF-binding protein 2" EXACT [UniProtKB:Q9UJY4] synonym: "Vear" EXACT [UniProtKB:Q9UJY4] synonym: "VHS domain and ear domain of gamma-adaptin" EXACT [UniProtKB:Q9UJY4] xref: EMBL:AAC05813.1 xref: EMBL:AAF05708.1 xref: EMBL:AAF35394.1 xref: EMBL:AAF42806.1 xref: EMBL:AAH00284.1 xref: EMBL:AAK38634.1 xref: EMBL:BAA83032.1 xref: UniProtKB:O14564 xref: UniProtKB:Q9NYN2 xref: UniProtKB:Q9UJY4 xref: UniProtKB:Q9UPS2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004697 ! GGA2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004389 ! ADP-ribosylation factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: participates_in CCO:I0005757 ! gga2-pin1 physical interaction relationship: participates_in CCO:I0015044 ! gga2-spg21 physical interaction relationship: participates_in CCO:I0015254 ! gga2-trim23 physical interaction [Term] id: CCO:B0005201 name: GLIS3_HUMAN def: "Zinc finger protein GLIS3" [UniProtKB:Q8NEA6] synonym: "GLI-similar 3" EXACT [UniProtKB:Q8NEA6] synonym: "Zinc finger protein 515" EXACT [UniProtKB:Q8NEA6] xref: EMBL:AAH33899.2 xref: EMBL:CAH70655.1 xref: EMBL:CAH72449.1 xref: EMBL:CAI39818.1 xref: UniProtKB:B1AL19 xref: UniProtKB:Q8NEA6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004703 ! GLIS3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0005758 ! glis3-sufu physical interaction [Term] id: CCO:B0005202 name: LDOC1_HUMAN def: "Protein LDOC1" [UniProtKB:O95751] synonym: "Leucine zipper protein down-regulated in cancer cells" EXACT [UniProtKB:O95751] xref: EMBL:AAH03104.1 xref: EMBL:BAA34364.1 xref: EMBL:CAC18891.1 xref: EMBL:CAG33369.1 xref: UniProtKB:O95751 xref: UniProtKB:Q6IAR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004975 ! LDOC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005759 ! fosl1-ldoc1 physical interaction relationship: participates_in CCO:I0005838 ! krt18-ldoc1 physical interaction relationship: participates_in CCO:I0014977 ! ldoc1-lnx physical interaction relationship: participates_in CCO:I0015021 ! ldoc1-poll physical interaction relationship: participates_in CCO:I0015121 ! drr1-ldoc1 physical interaction relationship: participates_in CCO:I0015132 ! krt15-ldoc1 physical interaction relationship: participates_in CCO:I0015151 ! ldoc1-znf408 physical interaction relationship: participates_in CCO:I0015153 ! atf4-ldoc1 physical interaction relationship: participates_in CCO:I0015184 ! dppa4-ldoc1 physical interaction relationship: participates_in CCO:I0015253 ! ldoc1-nrip1 physical interaction relationship: participates_in CCO:I0015267 ! gnl3l-ldoc1 physical interaction relationship: participates_in CCO:I0015346 ! aatf-ldoc1 physical interaction relationship: participates_in CCO:I0015359 ! ldoc1-znf250 physical interaction relationship: participates_in CCO:I0015364 ! ldoc1-znfn1a5 physical interaction relationship: participates_in CCO:I0015392 ! hgs-ldoc1 physical interaction relationship: participates_in CCO:I0015413 ! ablim1-ldoc1 physical interaction relationship: participates_in CCO:I0015522 ! ldoc1-utp14a physical interaction relationship: participates_in CCO:I0015627 ! ldoc1-smarcd1 physical interaction relationship: participates_in CCO:I0015773 ! ap1m1-ldoc1 physical interaction relationship: participates_in CCO:I0019421 ! ablim1-ldoc1-1 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0005203 name: Q96BX3_HUMAN def: "CUTC protein" [UniProtKB:Q96BX3] xref: EMBL:AAH15059.1 xref: UniProtKB:Q96BX3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006037 ! CUTC_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005760 ! cutc-pim2 physical interaction relationship: participates_in CCO:I0015527 ! cutc-spg21 physical interaction relationship: participates_in CCO:I0015753 ! cutc-nif3l1 physical interaction [Term] id: CCO:B0005204 name: TRI29_HUMAN def: "Tripartite motif-containing protein 29" [UniProtKB:Q14134] synonym: "Ataxia-telangiectasia group D-associated protein" EXACT [UniProtKB:Q14134] xref: EMBL:AAA35762.1 xref: EMBL:AAG50167.1 xref: EMBL:AAG50168.1 xref: EMBL:AAH17352.1 xref: UniProtKB:Q14134 xref: UniProtKB:Q96AA9 xref: UniProtKB:Q9BZY7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005829 ! TRIM29_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005761 ! mlh1-trim29 physical interaction relationship: participates_in CCO:I0005816 ! lzts2-trim29 physical interaction relationship: participates_in CCO:I0005901 ! trim29-ube2i physical interaction relationship: participates_in CCO:I0005905 ! mad1l1-trim29 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: transforms_into CCO:B0014531 ! TRI29_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0014532 ! TRI29_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0014533 ! TRI29_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0071551 ! TRI29_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0071552 ! TRI29_HUMAN-Phosphothreonine476 [Term] id: CCO:B0005205 name: IL1F5_HUMAN def: "Interleukin-1 family member 5" [UniProtKB:Q9UBH0] synonym: "FIL1 delta" EXACT [UniProtKB:Q9UBH0] synonym: "IL-1 delta" EXACT [UniProtKB:Q9UBH0] synonym: "IL-1-related protein 3" EXACT [UniProtKB:Q9UBH0] synonym: "IL-1F5" EXACT [UniProtKB:Q9UBH0] synonym: "IL-1HY1" EXACT [UniProtKB:Q9UBH0] synonym: "IL-1L1" EXACT [UniProtKB:Q9UBH0] synonym: "IL-1ra homolog 1" EXACT [UniProtKB:Q9UBH0] synonym: "IL-1RP3" EXACT [UniProtKB:Q9UBH0] synonym: "Interleukin-1 delta" EXACT [UniProtKB:Q9UBH0] synonym: "Interleukin-1 HY1" EXACT [UniProtKB:Q9UBH0] synonym: "Interleukin-1 receptor antagonist homolog 1" EXACT [UniProtKB:Q9UBH0] synonym: "Interleukin-1-like protein 1" EXACT [UniProtKB:Q9UBH0] xref: EMBL:AAF02757.1 xref: EMBL:AAF25210.1 xref: EMBL:AAF76981.1 xref: EMBL:AAF91274.1 xref: EMBL:AAH24747.1 xref: EMBL:AAQ89475.1 xref: EMBL:AAX59031.1 xref: EMBL:AAY14990.1 xref: EMBL:CAB59822.1 xref: EMBL:CAB59823.1 xref: EMBL:CAB67704.1 xref: EMBL:CAD29877.1 xref: UniProtKB:Q56AT9 xref: UniProtKB:Q7RTZ6 xref: UniProtKB:Q9UBH0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004880 ! IL1F5_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001451 ! interleukin-1 receptor binding relationship: has_function CCO:F0001454 ! interleukin-1 receptor antagonist activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0005763 ! il1f5-mcm6 physical interaction relationship: participates_in CCO:I0008962 ! smad3-sry-3 physical interaction relationship: participates_in CCO:I0015564 ! il1f5-ssbp2 physical interaction [Term] id: CCO:B0005206 name: NDKM_HUMAN def: "Nucleoside diphosphate kinase, mitochondrial precursor" [UniProtKB:O00746] synonym: "EC 2.7.4.6" EXACT [UniProtKB:O00746] synonym: "NDK" EXACT [UniProtKB:O00746] synonym: "NDP kinase, mitochondrial" EXACT [UniProtKB:O00746] synonym: "NDPKD" EXACT [UniProtKB:O00746] synonym: "nm23-H4" EXACT [UniProtKB:O00746] synonym: "Nucleoside diphosphate kinase D" EXACT [UniProtKB:O00746] xref: EMBL:AAH04880.1 xref: EMBL:AAH17067.1 xref: EMBL:AAK61230.1 xref: EMBL:CAA68877.1 xref: EMBL:CAC37288.1 xref: UniProtKB:O00746 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005169 ! NME4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000936 ! nucleoside diphosphate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000341 ! mitochondrial intermembrane space relationship: participates_in CCO:I0005765 ! nme1-nme4 physical interaction [Term] id: CCO:B0005207 name: K1C15_HUMAN def: "Keratin, type I cytoskeletal 15" [UniProtKB:P19012] synonym: "CK-15" EXACT [UniProtKB:P19012] synonym: "Cytokeratin-15" EXACT [UniProtKB:P19012] synonym: "K15" EXACT [UniProtKB:P19012] synonym: "Keratin-15" EXACT [UniProtKB:P19012] xref: EMBL:AAF27047.1 xref: EMBL:AAH02641.1 xref: EMBL:AAP35925.1 xref: EMBL:CAA30535.1 xref: UniProtKB:P19012 xref: UniProtKB:Q53XV8 xref: UniProtKB:Q9BUG4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004921 ! KRT15_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: participates_in CCO:I0005766 ! krt15-krt18 physical interaction relationship: participates_in CCO:I0005937 ! krt15-mad2l1bp physical interaction relationship: participates_in CCO:I0008694 ! krt15-psma1 physical interaction relationship: participates_in CCO:I0008696 ! krt15-psmc5 physical interaction relationship: participates_in CCO:I0014983 ! krt15-smarcd1 physical interaction relationship: participates_in CCO:I0015118 ! krt15-loc112869 physical interaction relationship: participates_in CCO:I0015132 ! krt15-ldoc1 physical interaction relationship: participates_in CCO:I0015266 ! krt15-tsg101 physical interaction relationship: participates_in CCO:I0015369 ! abi3-krt15 physical interaction relationship: participates_in CCO:I0015399 ! krt15-krt6a physical interaction relationship: participates_in CCO:I0015531 ! hoxb6-krt15 physical interaction relationship: participates_in CCO:I0015601 ! krt15-rhpn1 physical interaction relationship: participates_in CCO:I0015608 ! drr1-krt15 physical interaction relationship: participates_in CCO:I0015720 ! krt15-nif3l1 physical interaction [Term] id: CCO:B0005208 name: CT195_HUMAN def: "Uncharacterized protein C20orf195" [UniProtKB:Q9BVV2] xref: EMBL:AAH00912.1 xref: EMBL:CAI95748.1 xref: UniProtKB:Q9BVV2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004413 ! C20orf195_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005767 ! mgc5356-sssca1 physical interaction [Term] id: CCO:B0005209 name: GABP2_HUMAN def: "GA-binding protein subunit beta-2" [UniProtKB:Q8TAK5] synonym: "GABP subunit beta-2" EXACT [UniProtKB:Q8TAK5] synonym: "GABPB-2" EXACT [UniProtKB:Q8TAK5] xref: EMBL:AAH27033.1 xref: EMBL:BAC03833.1 xref: EMBL:CAI13351.1 xref: EMBL:CAI16392.1 xref: EMBL:EAW53474.1 xref: UniProtKB:Q8NAR5 xref: UniProtKB:Q8TAK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004678 ! GABPB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005210 name: USBP1_HUMAN def: "USH1C-binding protein 1" [UniProtKB:Q8N6Y0] synonym: "AIE-75-binding protein" EXACT [UniProtKB:Q8N6Y0] synonym: "MCC-2" EXACT [UniProtKB:Q8N6Y0] synonym: "Usher syndrome type-1C protein-binding protein 1" EXACT [UniProtKB:Q8N6Y0] xref: EMBL:AAH27910.1 xref: EMBL:BAB41203.1 xref: EMBL:BAB43978.1 xref: EMBL:BAC11443.1 xref: UniProtKB:Q8N6Y0 xref: UniProtKB:Q8NBX7 xref: UniProtKB:Q96KH3 xref: UniProtKB:Q9BYI8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005887 ! USHBP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005770 ! ccnk-ushbp1 physical interaction relationship: participates_in CCO:I0005899 ! kntc2-ushbp1 physical interaction relationship: participates_in CCO:I0005909 ! fancg-ushbp1 physical interaction relationship: participates_in CCO:I0006661 ! gfi1b-ushbp1 physical interaction relationship: participates_in CCO:I0015125 ! hgs-ushbp1 physical interaction relationship: participates_in CCO:I0015221 ! drr1-ushbp1 physical interaction relationship: participates_in CCO:I0015234 ! smarcd1-ushbp1 physical interaction relationship: participates_in CCO:I0015434 ! sertad3-ushbp1 physical interaction relationship: participates_in CCO:I0015470 ! med28-ushbp1 physical interaction relationship: participates_in CCO:I0019415 ! ushbp1-sertad3 physical interaction [Term] id: CCO:B0005211 name: DVL2_HUMAN def: "Segment polarity protein dishevelled homolog DVL-2" [UniProtKB:O14641] synonym: "Dishevelled-2" EXACT [UniProtKB:O14641] synonym: "DSH homolog 2" EXACT [UniProtKB:O14641] xref: EMBL:AAB65243.1 xref: EMBL:AAH14844.1 xref: UniProtKB:O14641 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004524 ! DVL2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005771 ! dvl2-mcrs1 physical interaction relationship: participates_in CCO:I0005862 ! dvl2-tp53 physical interaction relationship: participates_in CCO:I0006655 ! dvl2-tp53-1 physical interaction relationship: participates_in CCO:I0014984 ! dvl2-pcbd1 physical interaction relationship: participates_in CCO:I0014997 ! dvl2-usp5 physical interaction relationship: participates_in CCO:I0015013 ! dvl2-poli physical interaction relationship: participates_in CCO:I0015143 ! ap2m1-dvl2 physical interaction relationship: participates_in CCO:I0015181 ! c9orf100-dvl2 physical interaction relationship: participates_in CCO:I0015274 ! dvl2-tifa physical interaction relationship: participates_in CCO:I0015351 ! dvl2-tceb3b physical interaction relationship: participates_in CCO:I0015411 ! dvl2-rnps1 physical interaction relationship: participates_in CCO:I0015416 ! dvl2-flj12529 physical interaction relationship: participates_in CCO:I0015439 ! dvl2-snf8 physical interaction relationship: participates_in CCO:I0015485 ! dvl2-snip1 physical interaction relationship: participates_in CCO:I0015487 ! dvl2-q96br9 physical interaction relationship: participates_in CCO:I0015488 ! csnk1e-dvl2 physical interaction relationship: participates_in CCO:I0015490 ! dvl2-prpf3 physical interaction relationship: participates_in CCO:I0015516 ! bahd1-dvl2 physical interaction relationship: participates_in CCO:I0015536 ! bag3-dvl2 physical interaction relationship: participates_in CCO:I0015565 ! dvl2-traf2 physical interaction relationship: participates_in CCO:I0015594 ! dvl2-znf263 physical interaction relationship: participates_in CCO:I0015599 ! dvl2-rbpms physical interaction relationship: participates_in CCO:I0015607 ! c16orf48-dvl2 physical interaction relationship: participates_in CCO:I0015635 ! dvl2-loc90268 physical interaction relationship: participates_in CCO:I0015650 ! ap1m1-dvl2 physical interaction relationship: participates_in CCO:I0015676 ! dvl2-scam_1 physical interaction relationship: participates_in CCO:I0015721 ! dvl2-pepp2 physical interaction relationship: participates_in CCO:I0015733 ! dvl2-znf250 physical interaction relationship: participates_in CCO:I0015801 ! dvl2-znf165 physical interaction relationship: participates_in CCO:I0015811 ! dvl2-dvl2 physical interaction relationship: participates_in CCO:I0015812 ! dvl2-thap1 physical interaction relationship: participates_in CCO:I0017543 ! dvl2-a2bp1 physical interaction relationship: participates_in CCO:I0018923 ! atn1-dvl2 physical interaction relationship: participates_in CCO:I0019418 ! dvl2-dvl2-1 physical interaction relationship: participates_in CCO:I0019426 ! dvl2-znf165-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0005212 name: MAGAB_HUMAN def: "Melanoma-associated antigen 11" [UniProtKB:P43364] synonym: "Cancer/testis antigen 1.11" EXACT [UniProtKB:P43364] synonym: "CT1.11" EXACT [UniProtKB:P43364] synonym: "MAGE-11 antigen" EXACT [UniProtKB:P43364] xref: EMBL:AAA68870.1 xref: EMBL:AAH04479.2 xref: EMBL:AAW71787.1 xref: EMBL:BAC87161.1 xref: UniProtKB:P43364 xref: UniProtKB:Q5ETU4 xref: UniProtKB:Q6ZRZ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005016 ! MAGEA11_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005819 ! magea11-mlf1 physical interaction relationship: participates_in CCO:I0005897 ! cdkn2b-magea11 physical interaction relationship: participates_in CCO:I0005921 ! magea11-wtap physical interaction relationship: participates_in CCO:I0014986 ! birc2-magea11 physical interaction relationship: participates_in CCO:I0015008 ! magea11-mxd3 physical interaction relationship: participates_in CCO:I0015071 ! magea11-nif3l1 physical interaction relationship: participates_in CCO:I0015105 ! cova1-magea11 physical interaction relationship: participates_in CCO:I0015360 ! ewsr1-magea11 physical interaction relationship: participates_in CCO:I0015410 ! magea11-prdx3 physical interaction relationship: participates_in CCO:I0015489 ! fksg26-magea11 physical interaction relationship: participates_in CCO:I0015512 ! magea11-pnkp physical interaction relationship: participates_in CCO:I0015578 ! actn1-magea11 physical interaction relationship: participates_in CCO:I0015590 ! kiaa1849-magea11 physical interaction relationship: participates_in CCO:I0015649 ! magea11-rfp physical interaction relationship: participates_in CCO:I0015684 ! magea11-tcea2 physical interaction relationship: participates_in CCO:I0015790 ! magea11-znf655 physical interaction relationship: participates_in CCO:I0015800 ! magea11-med28 physical interaction relationship: participates_in CCO:I0019413 ! tcea2-magea11 physical interaction relationship: transforms_into CCO:B0012760 ! MAGAB_HUMAN-Phosphoserine76 [Term] id: CCO:B0005213 name: IKZF1_HUMAN def: "DNA-binding protein Ikaros" [UniProtKB:Q13422] synonym: "Ikaros family zinc finger protein 1" EXACT [UniProtKB:Q13422] synonym: "Lymphoid transcription factor LyF-1" EXACT [UniProtKB:Q13422] xref: EMBL:AAB50683.1 xref: EMBL:AAC50459.1 xref: EMBL:AAH18349.1 xref: UniProtKB:O00598 xref: UniProtKB:Q13422 xref: UniProtKB:Q8WVA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004877 ! IKZF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005773 ! ube2i-znfn1a1 physical interaction relationship: participates_in CCO:I0015244 ! ap2m1-znfn1a1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005214 name: ZN581_HUMAN def: "Zinc finger protein 581" [UniProtKB:Q9P0T4] xref: EMBL:AAF36109.2 xref: EMBL:AAH01219.1 xref: EMBL:AAH10097.1 xref: EMBL:AAH71620.1 xref: EMBL:AAH71845.1 xref: UniProtKB:Q9P0T4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005965 ! ZNF581_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005774 ! lzts2-znf581 physical interaction relationship: participates_in CCO:I0015236 ! dazap2-znf581 physical interaction relationship: participates_in CCO:I0015293 ! rbpms-znf581 physical interaction relationship: participates_in CCO:I0015466 ! hnrpc-znf581 physical interaction relationship: participates_in CCO:I0015577 ! trim23-znf581 physical interaction relationship: participates_in CCO:I0015595 ! plscr1-znf581 physical interaction relationship: participates_in CCO:I0015643 ! mdfi-znf581 physical interaction relationship: participates_in CCO:I0015679 ! krtap4_12-znf581 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005215 name: FBLN4_HUMAN def: "EGF-containing fibulin-like extracellular matrix protein 2 precursor" [UniProtKB:O95967] synonym: "FIBL-4" EXACT [UniProtKB:O95967] synonym: "Fibulin-4" EXACT [UniProtKB:O95967] synonym: "Protein UPH1" EXACT [UniProtKB:O95967] xref: EMBL:AAC62108.1 xref: EMBL:AAF65188.1 xref: EMBL:AAH10456.1 xref: EMBL:AAQ89258.1 xref: EMBL:CAA10791.2 xref: UniProtKB:O75967 xref: UniProtKB:O95967 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004616 ! EFEMP2_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005775 ! ccnk-efemp2 physical interaction relationship: participates_in CCO:I0005845 ! ccnd3-efemp2 physical interaction relationship: participates_in CCO:I0007641 ! gfi1b-efemp2 physical interaction relationship: participates_in CCO:I0007687 ! gfi1b-efemp2-1 physical interaction relationship: participates_in CCO:I0015061 ! drr1-efemp2 physical interaction relationship: participates_in CCO:I0015126 ! efemp2-znf263 physical interaction relationship: participates_in CCO:I0015617 ! efemp2-hoxa1 physical interaction relationship: participates_in CCO:I0015626 ! efemp2-znf426 physical interaction relationship: participates_in CCO:I0015694 ! efemp2-rhpn1 physical interaction relationship: participates_in CCO:I0015727 ! efemp2-pepp2 physical interaction relationship: participates_in CCO:I0017557 ! efemp2-atxn1 physical interaction relationship: participates_in CCO:I0019030 ! atxn1-efemp2 physical interaction relationship: participates_in CCO:I0019159 ! rere-efemp2 physical interaction relationship: participates_in CCO:I0019166 ! rere-efemp2-1 physical interaction relationship: participates_in CCO:I0019419 ! efemp2-pepp2-1 physical interaction [Term] id: CCO:B0005216 name: RIPK2_HUMAN def: "Receptor-interacting serine/threonine-protein kinase 2" [UniProtKB:O43353] synonym: "CARD-containing IL-1 beta ICE-kinase" EXACT [UniProtKB:O43353] synonym: "CARD-containing interleukin-1 beta-converting enzyme-associated kinase" EXACT [UniProtKB:O43353] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O43353] synonym: "Receptor-interacting protein 2" EXACT [UniProtKB:O43353] synonym: "RIP-2" EXACT [UniProtKB:O43353] synonym: "RIP-like-interacting CLARP kinase" EXACT [UniProtKB:O43353] xref: EMBL:AAC24561.1 xref: EMBL:AAC25668.1 xref: EMBL:AAC27722.1 xref: EMBL:AAC34970.1 xref: EMBL:AAH04553.1 xref: EMBL:AAQ89172.1 xref: EMBL:AAQ89173.1 xref: UniProtKB:O43353 xref: UniProtKB:Q6UWF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005493 ! RIPK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004370 ! LIM domain binding relationship: has_function CCO:F0008000 ! CARD domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005776 ! ripk2-ube2i physical interaction relationship: participates_in CCO:I0006394 ! ripk2-hspa2 physical interaction relationship: participates_in CCO:I0006395 ! ripk2-q9bva1 physical interaction relationship: participates_in CCO:I0008548 ! ripk2-myh10 physical interaction relationship: participates_in CCO:I0016906 ! ripk2-hspa1l physical interaction relationship: participates_in CCO:I0016907 ! ripk2-hspa8 physical interaction relationship: participates_in CCO:I0016908 ! ripk2-hspa6 physical interaction relationship: participates_in CCO:I0016909 ! ripk2-actg1 physical interaction relationship: participates_in CCO:I0016910 ! ripk2-ripk2 physical interaction relationship: participates_in CCO:I0016911 ! ripk2-hadhb physical interaction relationship: participates_in CCO:I0016912 ! ripk2-gemin4 physical interaction relationship: participates_in CCO:I0016913 ! ripk2-hsp70_1 physical interaction relationship: participates_in CCO:I0016914 ! ripk2-myh9 physical interaction relationship: participates_in CCO:I0016915 ! ripk2-eno1 physical interaction relationship: participates_in CCO:I0016916 ! ripk2-vim physical interaction relationship: participates_in CCO:I0016917 ! ripk2-hspca physical interaction relationship: participates_in CCO:I0016918 ! ripk2-gapd physical interaction relationship: participates_in CCO:I0016919 ! ripk2-tuba2 physical interaction relationship: participates_in CCO:I0016920 ! ripk2-myo1d physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002039 ! T cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0013878 ! RIPK2_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0013879 ! RIPK2_HUMAN-Phosphoserine531 [Term] id: CCO:B0005217 name: KCNRG_HUMAN def: "Putative potassium channel regulatory protein" [UniProtKB:Q8N5I3] synonym: "Potassium channel regulator" EXACT [UniProtKB:Q8N5I3] synonym: "Protein CLLD4" EXACT [UniProtKB:Q8N5I3] xref: EMBL:AAH32343.1 xref: EMBL:AAN06090.1 xref: EMBL:AAN06091.1 xref: EMBL:AAO11777.1 xref: EMBL:AAO11778.1 xref: EMBL:AAO27464.1 xref: EMBL:AAO27465.1 xref: EMBL:CAD38633.1 xref: UniProtKB:Q8IU75 xref: UniProtKB:Q8N3Q9 xref: UniProtKB:Q8N5I3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004934 ! KCNRG_human relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005777 ! ccnk-kcnrg physical interaction [Term] id: CCO:B0005218 name: ZMIZ2_HUMAN def: "Zinc finger MIZ domain-containing protein 2" [UniProtKB:Q8NF64] synonym: "PIAS-like protein Zimp7" EXACT [UniProtKB:Q8NF64] xref: EMBL:AAH21924.1 xref: EMBL:AAI10436.1 xref: EMBL:AAP22368.1 xref: EMBL:AAR85526.1 xref: EMBL:BAA34789.1 xref: EMBL:BAB67779.1 xref: EMBL:BAC03396.1 xref: EMBL:CAB66507.1 xref: EMBL:CAH56269.1 xref: UniProtKB:O94790 xref: UniProtKB:Q0VGB4 xref: UniProtKB:Q659A8 xref: UniProtKB:Q6JKL5 xref: UniProtKB:Q8NF64 xref: UniProtKB:Q8WTX8 xref: UniProtKB:Q96Q01 xref: UniProtKB:Q9BQH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005957 ! ZMIZ2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001793 ! nuclear replication fork relationship: participates_in CCO:I0005778 ! pin1-zimp7 physical interaction relationship: participates_in CCO:I0015400 ! sall2-zimp7 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005219 name: FKBP6_HUMAN def: "FK506-binding protein 6" [UniProtKB:O75344] synonym: "36 kDa FK506-binding protein" EXACT [UniProtKB:O75344] synonym: "EC 5.2.1.8" EXACT [UniProtKB:O75344] synonym: "FKBP-36" EXACT [UniProtKB:O75344] synonym: "Immunophilin FKBP36" EXACT [UniProtKB:O75344] synonym: "Peptidyl-prolyl cis-trans isomerase" EXACT [UniProtKB:O75344] synonym: "PPIase" EXACT [UniProtKB:O75344] synonym: "Rotamase" EXACT [UniProtKB:O75344] xref: EMBL:AAC64249.1 xref: EMBL:AAH36817.1 xref: UniProtKB:O75344 xref: UniProtKB:Q9UDS0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004648 ! FKBP6_human relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001658 ! FK506 binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005781 ! ccnk-fkbp6 physical interaction [Term] id: CCO:B0005220 name: STX11_HUMAN def: "Syntaxin-11" [UniProtKB:O75558] xref: EMBL:AAC24004.1 xref: EMBL:AAC24031.1 xref: EMBL:AAD02107.1 xref: EMBL:AAH33519.1 xref: EMBL:CAI22980.1 xref: EMBL:EAW47849.1 xref: UniProtKB:O75378 xref: UniProtKB:O75558 xref: UniProtKB:O95148 xref: UniProtKB:Q5TCL6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005700 ! STX11_human relationship: has_function CCO:F0001631 ! SNAP receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005782 ! ccnk-stx11 physical interaction relationship: participates_in CCO:I0008803 ! stx11-psma3 physical interaction relationship: participates_in CCO:I0008811 ! stx11-psmc3 physical interaction relationship: participates_in CCO:I0015086 ! stx11-taf6l physical interaction relationship: participates_in CCO:I0015256 ! snap25-stx11-1 physical interaction relationship: participates_in CCO:I0019837 ! snap25-stx11 physical interaction [Term] id: CCO:B0005221 name: H31_HUMAN def: "Histone H3.1" [UniProtKB:P68431] synonym: "H3/a" EXACT [UniProtKB:P68431] synonym: "H3/b" EXACT [UniProtKB:P68431] synonym: "H3/c" EXACT [UniProtKB:P68431] synonym: "H3/d" EXACT [UniProtKB:P68431] synonym: "H3/f" EXACT [UniProtKB:P68431] synonym: "H3/h" EXACT [UniProtKB:P68431] synonym: "H3/i" EXACT [UniProtKB:P68431] synonym: "H3/j" EXACT [UniProtKB:P68431] synonym: "H3/k" EXACT [UniProtKB:P68431] synonym: "H3/l" EXACT [UniProtKB:P68431] xref: EMBL:AAA52651.1 xref: EMBL:AAA63185.1 xref: EMBL:AAH07518.1 xref: EMBL:AAH12185.1 xref: EMBL:AAH31333.1 xref: EMBL:AAH33095.1 xref: EMBL:AAH52981.1 xref: EMBL:AAH66245.1 xref: EMBL:AAH66246.1 xref: EMBL:AAH66247.1 xref: EMBL:AAH66884.1 xref: EMBL:AAH67490.1 xref: EMBL:AAH67491.1 xref: EMBL:AAH67492.1 xref: EMBL:AAH67493.1 xref: EMBL:AAH67494.1 xref: EMBL:AAH69133.1 xref: EMBL:AAH69303.1 xref: EMBL:AAH69305.2 xref: EMBL:AAH69818.1 xref: EMBL:AAH79835.1 xref: EMBL:AAH96128.1 xref: EMBL:AAH96129.1 xref: EMBL:AAH96130.1 xref: EMBL:AAH96131.1 xref: EMBL:AAH96132.1 xref: EMBL:AAH96133.1 xref: EMBL:AAH96134.1 xref: EMBL:AAH99630.1 xref: EMBL:AAI27611.1 xref: EMBL:AAN10051.1 xref: EMBL:AAN10052.1 xref: EMBL:AAN10053.1 xref: EMBL:AAN10054.1 xref: EMBL:AAN10055.1 xref: EMBL:AAN10056.1 xref: EMBL:AAN10057.1 xref: EMBL:AAN10058.1 xref: EMBL:AAN10059.1 xref: EMBL:AAN10060.1 xref: EMBL:CAA15670.1 xref: EMBL:CAA24952.1 xref: EMBL:CAA40407.1 xref: EMBL:CAA58540.1 xref: EMBL:CAA86403.1 xref: EMBL:CAB02546.1 xref: EMBL:CAB02547.1 xref: EMBL:CAB02548.1 xref: EMBL:CAB06030.1 xref: EMBL:CAB06032.1 xref: EMBL:CAB11424.1 xref: EMBL:CAC03412.1 xref: EMBL:CAC03413.1 xref: EMBL:CAC03416.1 xref: EMBL:CAC03421.1 xref: EMBL:CAD24076.1 xref: EMBL:CAG46656.1 xref: EMBL:CAG46780.1 xref: EMBL:CAG46808.1 xref: EMBL:CAG46811.1 xref: UniProtKB:A0PJT7 xref: UniProtKB:P02295 xref: UniProtKB:P02296 xref: UniProtKB:P16106 xref: UniProtKB:P68431 xref: UniProtKB:Q6ISV8 xref: UniProtKB:Q6NWP8 xref: UniProtKB:Q6NWP9 xref: UniProtKB:Q6NXU4 xref: UniProtKB:Q71DJ3 xref: UniProtKB:Q93081 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004749 ! HIST1H3A_human relationship: encoded_by CCO:G0004750 ! HIST1H3B_human relationship: encoded_by CCO:G0004751 ! HIST1H3C_human relationship: encoded_by CCO:G0004752 ! HIST1H3D_human relationship: encoded_by CCO:G0004753 ! HIST1H3E_human relationship: encoded_by CCO:G0004754 ! HIST1H3F_human relationship: encoded_by CCO:G0004755 ! HIST1H3G_human relationship: encoded_by CCO:G0004756 ! HIST1H3H_human relationship: encoded_by CCO:G0004757 ! HIST1H3I_human relationship: encoded_by CCO:G0004758 ! HIST1H3J_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005783 ! hist1h3a-nasp physical interaction relationship: participates_in CCO:I0006004 ! daxx-dek-1 physical interaction relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0006807 ! h3-caf1 physical interaction relationship: participates_in CCO:I0007197 ! egfr-h3fa-1 colocalization relationship: participates_in CCO:I0007726 ! h3fa-suv39h1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0019276 ! atxn7-trrap-2 acetylation relationship: participates_in CCO:I0019455 ! h3_1-jmjd2a colocalization relationship: transforms_into CCO:B0012023 ! H31_HUMAN-Phosphothreonine4 relationship: transforms_into CCO:B0012024 ! H31_HUMAN-N6-acetyllysine5 relationship: transforms_into CCO:B0012025 ! H31_HUMAN-N6-methyllysine5 relationship: transforms_into CCO:B0012026 ! H31_HUMAN-Citrulline9 relationship: transforms_into CCO:B0012027 ! H31_HUMAN-dimethylarginine9 relationship: transforms_into CCO:B0012028 ! H31_HUMAN-N6,N6,N6-trimethyllysine10 relationship: transforms_into CCO:B0012029 ! H31_HUMAN-N6,N6-dimethyllysine10 relationship: transforms_into CCO:B0012030 ! H31_HUMAN-N6-acetyllysine10 relationship: transforms_into CCO:B0012031 ! H31_HUMAN-N6-methyllysine10 relationship: transforms_into CCO:B0012032 ! H31_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0012033 ! H31_HUMAN-Phosphothreonine12 relationship: transforms_into CCO:B0012034 ! H31_HUMAN-N6-acetyllysine15 relationship: transforms_into CCO:B0012035 ! H31_HUMAN-dimethylarginine18 relationship: transforms_into CCO:B0012036 ! H31_HUMAN-Citrulline18 relationship: transforms_into CCO:B0012037 ! H31_HUMAN-N6-acetyllysine19 relationship: transforms_into CCO:B0012038 ! H31_HUMAN-N6-methyllysine19 relationship: transforms_into CCO:B0012039 ! H31_HUMAN-N6-acetyllysine24 relationship: transforms_into CCO:B0012040 ! H31_HUMAN-N6-methyllysine24 relationship: transforms_into CCO:B0012041 ! H31_HUMAN-N6,N6,N6-trimethyllysine28 relationship: transforms_into CCO:B0012042 ! H31_HUMAN-N6,N6-dimethyllysine28 relationship: transforms_into CCO:B0012043 ! H31_HUMAN-N6-acetyllysine28 relationship: transforms_into CCO:B0012044 ! H31_HUMAN-N6-methyllysine28 relationship: transforms_into CCO:B0012045 ! H31_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0012046 ! H31_HUMAN-N6,N6,N6-trimethyllysine37 relationship: transforms_into CCO:B0012047 ! H31_HUMAN-N6,N6-dimethyllysine37 relationship: transforms_into CCO:B0012048 ! H31_HUMAN-N6-acetyllysine37 relationship: transforms_into CCO:B0012049 ! H31_HUMAN-N6-methyllysine37 relationship: transforms_into CCO:B0012050 ! H31_HUMAN-N6-methyllysine38 relationship: transforms_into CCO:B0012051 ! H31_HUMAN-N6,N6,N6-trimethyllysine57 relationship: transforms_into CCO:B0012052 ! H31_HUMAN-N6-acetyllysine57 relationship: transforms_into CCO:B0012053 ! H31_HUMAN-N6-methyllysine57 relationship: transforms_into CCO:B0012054 ! H31_HUMAN-N6-methyllysine65 relationship: transforms_into CCO:B0012055 ! H31_HUMAN-N6,N6,N6-trimethyllysine80 relationship: transforms_into CCO:B0012056 ! H31_HUMAN-N6,N6-dimethyllysine80 relationship: transforms_into CCO:B0012057 ! H31_HUMAN-N6-acetyllysine80 relationship: transforms_into CCO:B0012058 ! H31_HUMAN-N6-methyllysine80 relationship: transforms_into CCO:B0012059 ! H31_HUMAN-N6-methyllysine123 [Term] id: CCO:B0005223 name: RBM8A_HUMAN def: "RNA-binding protein 8A" [UniProtKB:Q9Y5S9] synonym: "Binder of OVCA1-1" EXACT [UniProtKB:Q9Y5S9] synonym: "BOV-1" EXACT [UniProtKB:Q9Y5S9] synonym: "Ribonucleoprotein RBM8A" EXACT [UniProtKB:Q9Y5S9] synonym: "RNA-binding motif protein 8A" EXACT [UniProtKB:Q9Y5S9] synonym: "RNA-binding protein Y14" EXACT [UniProtKB:Q9Y5S9] xref: EMBL:AAD21089.1 xref: EMBL:AAF29078.1 xref: EMBL:AAF37551.1 xref: EMBL:AAG14951.1 xref: EMBL:AAG16781.1 xref: EMBL:AAG16782.1 xref: EMBL:AAG27091.1 xref: EMBL:AAH17088.1 xref: EMBL:AAH71577.1 xref: EMBL:AAL26999.1 xref: EMBL:CAG46604.1 xref: EMBL:CAG46622.1 xref: UniProtKB:Q6FHD1 xref: UniProtKB:Q6IQ40 xref: UniProtKB:Q9GZX8 xref: UniProtKB:Q9NZI4 xref: UniProtKB:Q9Y5S9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005450 ! RBM8A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005785 ! mcm7-rbm8a physical interaction relationship: participates_in CCO:I0017741 ! rbm8a-ddx48-1 physical interaction relationship: participates_in CCO:I0017948 ! casc3-ddx48 physical interaction relationship: participates_in CCO:I0018063 ! rbm8a-ddx48-2 physical interaction relationship: transforms_into CCO:B0013795 ! RBM8A_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0013796 ! RBM8A_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0013797 ! RBM8A_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0013798 ! RBM8A_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0069823 ! RBM8A_HUMAN-Phosphoserine56 [Term] id: CCO:B0005224 name: PDLI7_HUMAN def: "PDZ and LIM domain protein 7" [UniProtKB:Q9NR12] synonym: "LIM mineralization protein" EXACT [UniProtKB:Q9NR12] synonym: "LMP" EXACT [UniProtKB:Q9NR12] synonym: "Protein enigma" EXACT [UniProtKB:Q9NR12] xref: EMBL:AAC37565.1 xref: EMBL:AAF76152.1 xref: EMBL:AAH01093.1 xref: EMBL:AAH14521.1 xref: EMBL:AAH67806.1 xref: EMBL:AAH84575.1 xref: EMBL:AAK30567.1 xref: EMBL:AAK30568.1 xref: EMBL:AAK30569.1 xref: UniProtKB:Q14250 xref: UniProtKB:Q5XG82 xref: UniProtKB:Q6NVZ5 xref: UniProtKB:Q96C91 xref: UniProtKB:Q9BXB8 xref: UniProtKB:Q9BXB9 xref: UniProtKB:Q9NR12 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005293 ! PDLIM7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0005788 ! pdlim7-ube2i physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015634 ! bsg-pdlim7 physical interaction relationship: participates_in CCO:I0015697 ! gem-pdlim7 physical interaction relationship: participates_in CCO:I0015707 ! pdlim7-znf165 physical interaction relationship: transforms_into CCO:B0013475 ! PDLI7_HUMAN-Phosphothreonine251 relationship: transforms_into CCO:B0069188 ! PDLI7_HUMAN-Phosphoserine247 [Term] id: CCO:B0005225 name: EWS_HUMAN def: "RNA-binding protein EWS" [UniProtKB:Q01844] synonym: "Ewing sarcoma breakpoint region 1 protein" EXACT [UniProtKB:Q01844] synonym: "EWS oncogene" EXACT [UniProtKB:Q01844] xref: EMBL:AAH04817.1 xref: EMBL:BAA31990.1 xref: EMBL:CAA47350.1 xref: EMBL:CAA51489.1 xref: EMBL:CAA69177.1 xref: EMBL:CAA70044.1 xref: UniProtKB:Q01844 xref: UniProtKB:Q92635 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004593 ! EWSR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005790 ! ewsr1-mtcp1 physical interaction relationship: participates_in CCO:I0005922 ! ewsr1-matk physical interaction relationship: participates_in CCO:I0005932 ! ewsr1-suv39h2 physical interaction relationship: participates_in CCO:I0006651 ! ewsr1-hbp1 physical interaction relationship: participates_in CCO:I0006652 ! ewsr1-hspa2 physical interaction relationship: participates_in CCO:I0008959 ! ewsr1-rps15a physical interaction relationship: participates_in CCO:I0014952 ! ewsr1-hhgp physical interaction relationship: participates_in CCO:I0014963 ! ewsr1-zdhhc3 physical interaction relationship: participates_in CCO:I0014966 ! ewsr1-msc physical interaction relationship: participates_in CCO:I0014972 ! ewsr1-mgc34821 physical interaction relationship: participates_in CCO:I0015014 ! ewsr1-myo1f physical interaction relationship: participates_in CCO:I0015016 ! ewsr1-mgc2749 physical interaction relationship: participates_in CCO:I0015066 ! ewsr1-hcg3 physical interaction relationship: participates_in CCO:I0015069 ! ewsr1-fasn physical interaction relationship: participates_in CCO:I0015078 ! ewsr1-nle1 physical interaction relationship: participates_in CCO:I0015081 ! c9orf65-ewsr1 physical interaction relationship: participates_in CCO:I0015084 ! ewsr1-wwp2 physical interaction relationship: participates_in CCO:I0015107 ! ewsr1-ndufb1 physical interaction relationship: participates_in CCO:I0015116 ! bnip3l-ewsr1 physical interaction relationship: participates_in CCO:I0015120 ! ewsr1-nsun4 physical interaction relationship: participates_in CCO:I0015129 ! ewsr1-hrb2 physical interaction relationship: participates_in CCO:I0015147 ! ewsr1-wwp1 physical interaction relationship: participates_in CCO:I0015161 ! ewsr1-flj22318 physical interaction relationship: participates_in CCO:I0015176 ! ewsr1-slc1a1 physical interaction relationship: participates_in CCO:I0015177 ! ewsr1-rasl11b physical interaction relationship: participates_in CCO:I0015189 ! dffa-ewsr1 physical interaction relationship: participates_in CCO:I0015199 ! ewsr1-wdr37 physical interaction relationship: participates_in CCO:I0015230 ! c11orf16-ewsr1 physical interaction relationship: participates_in CCO:I0015240 ! ewsr1-rnf183 physical interaction relationship: participates_in CCO:I0015260 ! ewsr1-rbpms physical interaction relationship: participates_in CCO:I0015263 ! eif2ak4-ewsr1 physical interaction relationship: participates_in CCO:I0015264 ! ewsr1-kel physical interaction relationship: participates_in CCO:I0015271 ! ewsr1-myoz2 physical interaction relationship: participates_in CCO:I0015273 ! c1orf117-ewsr1 physical interaction relationship: participates_in CCO:I0015285 ! ewsr1-hmga1 physical interaction relationship: participates_in CCO:I0015301 ! ewsr1-nppb physical interaction relationship: participates_in CCO:I0015312 ! ewsr1-herpud1 physical interaction relationship: participates_in CCO:I0015315 ! ewsr1-prv1 physical interaction relationship: participates_in CCO:I0015325 ! ewsr1-rpl31 physical interaction relationship: participates_in CCO:I0015331 ! ewsr1-tcfl1 physical interaction relationship: participates_in CCO:I0015332 ! actl6a-ewsr1 physical interaction relationship: participates_in CCO:I0015344 ! ewsr1-rad23a physical interaction relationship: participates_in CCO:I0015360 ! ewsr1-magea11 physical interaction relationship: participates_in CCO:I0015368 ! cfdp1-ewsr1 physical interaction relationship: participates_in CCO:I0015375 ! cxadr-ewsr1 physical interaction relationship: participates_in CCO:I0015381 ! ewsr1-znf165 physical interaction relationship: participates_in CCO:I0015384 ! ewsr1-ssbp2 physical interaction relationship: participates_in CCO:I0015385 ! c18orf10-ewsr1 physical interaction relationship: participates_in CCO:I0015387 ! ewsr1-rab37 physical interaction relationship: participates_in CCO:I0015405 ! cetp-ewsr1 physical interaction relationship: participates_in CCO:I0015409 ! ewsr1-ndufv1 physical interaction relationship: participates_in CCO:I0015438 ! dlc2-ewsr1 physical interaction relationship: participates_in CCO:I0015475 ! ewsr1-q8n4d0 physical interaction relationship: participates_in CCO:I0015476 ! dkfzp434h1428-ewsr1 physical interaction relationship: participates_in CCO:I0015477 ! c13orf21-ewsr1 physical interaction relationship: participates_in CCO:I0015492 ! ewsr1-gnpda1 physical interaction relationship: participates_in CCO:I0015517 ! elavl3-ewsr1 physical interaction relationship: participates_in CCO:I0015524 ! elavl4-ewsr1 physical interaction relationship: participates_in CCO:I0015525 ! ewsr1-lilra3 physical interaction relationship: participates_in CCO:I0015543 ! bad-ewsr1 physical interaction relationship: participates_in CCO:I0015555 ! ccdc7-ewsr1 physical interaction relationship: participates_in CCO:I0015557 ! ewsr1-mrps18b physical interaction relationship: participates_in CCO:I0015609 ! ewsr1-tspan3 physical interaction relationship: participates_in CCO:I0015618 ! ewsr1-ggabp physical interaction relationship: participates_in CCO:I0015639 ! ewsr1-trim37 physical interaction relationship: participates_in CCO:I0015645 ! ewsr1-ntng2 physical interaction relationship: participates_in CCO:I0015654 ! ewsr1-flj12529 physical interaction relationship: participates_in CCO:I0015673 ! ewsr1-seli physical interaction relationship: participates_in CCO:I0015677 ! ewsr1-myl6 physical interaction relationship: participates_in CCO:I0015680 ! ewsr1-smad4 physical interaction relationship: participates_in CCO:I0015692 ! ewsr1-tmsb4y physical interaction relationship: participates_in CCO:I0015698 ! ewsr1-q8n4c1 physical interaction relationship: participates_in CCO:I0015708 ! ewsr1-mvk physical interaction relationship: participates_in CCO:I0015712 ! c14orf32-ewsr1 physical interaction relationship: participates_in CCO:I0015719 ! ewsr1-mdfi physical interaction relationship: participates_in CCO:I0015725 ! ewsr1-mtmr9 physical interaction relationship: participates_in CCO:I0015731 ! ewsr1-plscr1 physical interaction relationship: participates_in CCO:I0015742 ! ewsr1-pdhx physical interaction relationship: participates_in CCO:I0015744 ! c10orf12-ewsr1 physical interaction relationship: participates_in CCO:I0015754 ! ewsr1-pepp2 physical interaction relationship: participates_in CCO:I0015771 ! ewsr1-sall2 physical interaction relationship: participates_in CCO:I0015784 ! agt-ewsr1 physical interaction relationship: participates_in CCO:I0015788 ! ewsr1-kcnmb1 physical interaction relationship: participates_in CCO:I0017550 ! ewsr1-atn1 physical interaction relationship: participates_in CCO:I0017571 ! ewsr1-atxn3 physical interaction relationship: participates_in CCO:I0017579 ! ewsr1-ercc5 physical interaction relationship: participates_in CCO:I0017580 ! ewsr1-pcbp1 physical interaction relationship: participates_in CCO:I0018924 ! atn1-ewsr1 physical interaction relationship: participates_in CCO:I0019176 ! usp7-ewsr1 physical interaction relationship: participates_in CCO:I0019431 ! ewsr1-znf165-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011776 ! EWS_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0011777 ! EWS_HUMAN-Asymmetric dimethylarginine300 relationship: transforms_into CCO:B0011778 ! EWS_HUMAN-Asymmetric dimethylarginine302 relationship: transforms_into CCO:B0011779 ! EWS_HUMAN-Asymmetric dimethylarginine304 relationship: transforms_into CCO:B0011780 ! EWS_HUMAN-Asymmetric dimethylarginine309 relationship: transforms_into CCO:B0011781 ! EWS_HUMAN-Asymmetric dimethylarginine314 relationship: transforms_into CCO:B0011782 ! EWS_HUMAN-Asymmetric dimethylarginine317 relationship: transforms_into CCO:B0011783 ! EWS_HUMAN-Asymmetric dimethylarginine321 relationship: transforms_into CCO:B0011784 ! EWS_HUMAN-Asymmetric dimethylarginine455 relationship: transforms_into CCO:B0011785 ! EWS_HUMAN-Asymmetric dimethylarginine464 relationship: transforms_into CCO:B0011786 ! EWS_HUMAN-dimethylarginine471 relationship: transforms_into CCO:B0011787 ! EWS_HUMAN-Omega-N-methylarginine471 relationship: transforms_into CCO:B0011788 ! EWS_HUMAN-Asymmetric dimethylarginine490 relationship: transforms_into CCO:B0011789 ! EWS_HUMAN-Asymmetric dimethylarginine494 relationship: transforms_into CCO:B0011790 ! EWS_HUMAN-Asymmetric dimethylarginine500 relationship: transforms_into CCO:B0011791 ! EWS_HUMAN-Asymmetric dimethylarginine503 relationship: transforms_into CCO:B0011792 ! EWS_HUMAN-Asymmetric dimethylarginine506 relationship: transforms_into CCO:B0011793 ! EWS_HUMAN-Asymmetric dimethylarginine563 relationship: transforms_into CCO:B0011794 ! EWS_HUMAN-Asymmetric dimethylarginine565 relationship: transforms_into CCO:B0011795 ! EWS_HUMAN-Asymmetric dimethylarginine572 relationship: transforms_into CCO:B0011796 ! EWS_HUMAN-Asymmetric dimethylarginine575 relationship: transforms_into CCO:B0011797 ! EWS_HUMAN-Asymmetric dimethylarginine581 relationship: transforms_into CCO:B0011798 ! EWS_HUMAN-Asymmetric dimethylarginine589 relationship: transforms_into CCO:B0011799 ! EWS_HUMAN-Asymmetric dimethylarginine592 relationship: transforms_into CCO:B0011800 ! EWS_HUMAN-Asymmetric dimethylarginine596 relationship: transforms_into CCO:B0011801 ! EWS_HUMAN-Asymmetric dimethylarginine600 relationship: transforms_into CCO:B0011802 ! EWS_HUMAN-Asymmetric dimethylarginine603 relationship: transforms_into CCO:B0011803 ! EWS_HUMAN-Asymmetric dimethylarginine607 relationship: transforms_into CCO:B0011804 ! EWS_HUMAN-Asymmetric dimethylarginine615 relationship: transforms_into CCO:B0011805 ! EWS_HUMAN-Asymmetric dimethylarginine633 relationship: transforms_into CCO:B0011806 ! EWS_HUMAN-Asymmetric dimethylarginine636 [Term] id: CCO:B0005228 name: ZN580_HUMAN def: "Zinc finger protein 580" [UniProtKB:Q9UK33] synonym: "LDL-induced EC protein" EXACT [UniProtKB:Q9UK33] xref: EMBL:AAD56549.1 xref: EMBL:AAH17698.1 xref: EMBL:CAB94389.1 xref: UniProtKB:Q9NPP7 xref: UniProtKB:Q9UK33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005964 ! ZNF580_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005793 ! rad54b-znf580 physical interaction relationship: participates_in CCO:I0015237 ! tsc22d4-znf580 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005229 name: MARK3_HUMAN def: "MAP/microtubule affinity-regulating kinase 3" [UniProtKB:P27448] synonym: "C-TAK1" EXACT [UniProtKB:P27448] synonym: "Cdc25C-associated protein kinase 1" EXACT [UniProtKB:P27448] synonym: "cTAK1" EXACT [UniProtKB:P27448] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P27448] synonym: "Protein kinase STK10" EXACT [UniProtKB:P27448] synonym: "Ser/Thr protein kinase PAR-1" EXACT [UniProtKB:P27448] synonym: "Serine/threonine protein kinase p78" EXACT [UniProtKB:P27448] xref: EMBL:AAA59991.1 xref: EMBL:AAC15093.1 xref: EMBL:AAD48007.1 xref: EMBL:AAD51631.1 xref: EMBL:AAH24773.1 xref: EMBL:AAK82367.1 xref: EMBL:AAL69982.1 xref: UniProtKB:O60219 xref: UniProtKB:P27448 xref: UniProtKB:Q8TB41 xref: UniProtKB:Q8WX83 xref: UniProtKB:Q96RG1 xref: UniProtKB:Q9UMY9 xref: UniProtKB:Q9UN34 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005027 ! MARK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005794 ! mark3-sfn physical interaction relationship: participates_in CCO:I0006258 ! qsk-ywhaz-3 physical interaction relationship: participates_in CCO:I0007837 ! qsk-ywhaz-2 physical interaction relationship: participates_in CCO:I0018272 ! mark3-ywhaz-1 physical interaction relationship: participates_in CCO:I0018841 ! asb13-mark3-1 physical interaction relationship: participates_in CCO:I0019405 ! mark3-tcea2-1 physical interaction relationship: participates_in CCO:I0020185 ! tcea2-mark3 physical interaction relationship: participates_in CCO:I0020589 ! mark3-asb13 physical interaction relationship: transforms_into CCO:B0012772 ! MARK3_HUMAN-Phosphothreonine234 relationship: transforms_into CCO:B0012773 ! MARK3_HUMAN-Phosphoserine442 relationship: transforms_into CCO:B0012774 ! MARK3_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0012775 ! MARK3_HUMAN-Phosphoserine624 relationship: transforms_into CCO:B0067994 ! MARK3_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0067995 ! MARK3_HUMAN-Phosphoserine566 relationship: transforms_into CCO:B0067996 ! MARK3_HUMAN-Phosphothreonine572 relationship: transforms_into CCO:B0067997 ! MARK3_HUMAN-Phosphothreonine614 [Term] id: CCO:B0005230 name: Q8IVD8_HUMAN def: "Zinc finger protein 646" [UniProtKB:Q8IVD8] synonym: "Zinc finger protein 646, isoform CRA_a" EXACT [UniProtKB:Q8IVD8] xref: EMBL:AAH35589.1 xref: EMBL:EAW52170.1 xref: UniProtKB:Q8IVD8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006018 ! ZNF646_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0005795 ! ube2i-znf646 physical interaction relationship: participates_in CCO:I0015192 ! traf2-znf646 physical interaction relationship: participates_in CCO:I0015529 ! mdfi-znf646 physical interaction [Term] id: CCO:B0005231 name: ZBED1_HUMAN def: "Zinc finger BED domain-containing protein 1" [UniProtKB:O96006] synonym: "dREF homolog" EXACT [UniProtKB:O96006] synonym: "Putative Ac-like transposable element" EXACT [UniProtKB:O96006] xref: EMBL:AAH15030.1 xref: EMBL:BAA34505.2 xref: EMBL:CAA76545.1 xref: EMBL:CAA76660.1 xref: UniProtKB:O96006 xref: UniProtKB:Q96BY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005951 ! ZBED1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001161 ! transposase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005796 ! fancg-zbed1x physical interaction relationship: participates_in CCO:I0005876 ! ube2i-zbed1x physical interaction relationship: participates_in CCO:I0015094 ! nif3l1-zbed1x physical interaction relationship: participates_in CCO:I0015133 ! trappc2-zbed1x physical interaction relationship: participates_in CCO:I0015165 ! xab1-zbed1x physical interaction [Term] id: CCO:B0005232 name: MDFI_HUMAN def: "MyoD family inhibitor" [UniProtKB:Q99750] synonym: "Myogenic repressor I-mf" EXACT [UniProtKB:Q99750] xref: EMBL:AAB39748.1 xref: EMBL:AAH07836.1 xref: EMBL:CAB54148.1 xref: UniProtKB:Q99750 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005051 ! MDFI_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005797 ! dusp6-mdfi physical interaction relationship: participates_in CCO:I0005810 ! mdfi-pin1 physical interaction relationship: participates_in CCO:I0005872 ! mcm5-mdfi physical interaction relationship: participates_in CCO:I0014965 ! ddx19a-mdfi physical interaction relationship: participates_in CCO:I0014981 ! hoxa1-mdfi physical interaction relationship: participates_in CCO:I0014985 ! aasdhppt-mdfi physical interaction relationship: participates_in CCO:I0014991 ! fzd9-mdfi physical interaction relationship: participates_in CCO:I0015031 ! c18orf56-mdfi physical interaction relationship: participates_in CCO:I0015045 ! bahd1-mdfi physical interaction relationship: participates_in CCO:I0015048 ! dkk1-mdfi physical interaction relationship: participates_in CCO:I0015052 ! ebi3-mdfi physical interaction relationship: participates_in CCO:I0015055 ! mdfi-znf426 physical interaction relationship: participates_in CCO:I0015058 ! c18orf45-mdfi physical interaction relationship: participates_in CCO:I0015073 ! mdfi-six1 physical interaction relationship: participates_in CCO:I0015079 ! chic2-mdfi physical interaction relationship: participates_in CCO:I0015085 ! mdfi-mdfi physical interaction relationship: participates_in CCO:I0015114 ! flj36046-mdfi physical interaction relationship: participates_in CCO:I0015122 ! kiaa0514-mdfi physical interaction relationship: participates_in CCO:I0015158 ! c20orf75-mdfi physical interaction relationship: participates_in CCO:I0015168 ! aqp1-mdfi physical interaction relationship: participates_in CCO:I0015175 ! mdfi-nr1h2 physical interaction relationship: participates_in CCO:I0015191 ! mdfi-znf679 physical interaction relationship: participates_in CCO:I0015195 ! mdfi-slc35a2 physical interaction relationship: participates_in CCO:I0015196 ! cry1-mdfi physical interaction relationship: participates_in CCO:I0015203 ! mdfi-zbtb25 physical interaction relationship: participates_in CCO:I0015206 ! flj20850-mdfi physical interaction relationship: participates_in CCO:I0015220 ! c12orf12-mdfi physical interaction relationship: participates_in CCO:I0015222 ! c16orf48-mdfi physical interaction relationship: participates_in CCO:I0015229 ! aqp5-mdfi physical interaction relationship: participates_in CCO:I0015242 ! dhrs1-mdfi physical interaction relationship: participates_in CCO:I0015249 ! mdfi-serf2 physical interaction relationship: participates_in CCO:I0015262 ! mdfi-znf559 physical interaction relationship: participates_in CCO:I0015275 ! mdfi-mfsd3 physical interaction relationship: participates_in CCO:I0015294 ! fastk-mdfi physical interaction relationship: participates_in CCO:I0015316 ! mdfi-znf607 physical interaction relationship: participates_in CCO:I0015319 ! mdfi-thap7 physical interaction relationship: participates_in CCO:I0015321 ! mdfi-otx1 physical interaction relationship: participates_in CCO:I0015335 ! c6orf4-mdfi physical interaction relationship: participates_in CCO:I0015340 ! ilf3-mdfi physical interaction relationship: participates_in CCO:I0015371 ! c8orf32-mdfi physical interaction relationship: participates_in CCO:I0015386 ! loc286075-mdfi physical interaction relationship: participates_in CCO:I0015398 ! mdfi-znf439 physical interaction relationship: participates_in CCO:I0015404 ! hoxb9-mdfi physical interaction relationship: participates_in CCO:I0015415 ! fbxw5-mdfi physical interaction relationship: participates_in CCO:I0015417 ! mdfi-rfx2 physical interaction relationship: participates_in CCO:I0015421 ! jm11-mdfi physical interaction relationship: participates_in CCO:I0015454 ! mdfi-tinagl1 physical interaction relationship: participates_in CCO:I0015456 ! mdfi-znf408 physical interaction relationship: participates_in CCO:I0015465 ! mdfi-spg7 physical interaction relationship: participates_in CCO:I0015472 ! mdfi-znf136 physical interaction relationship: participates_in CCO:I0015501 ! catsper1-mdfi physical interaction relationship: participates_in CCO:I0015529 ! mdfi-znf646 physical interaction relationship: participates_in CCO:I0015530 ! mdfi-npdc1 physical interaction relationship: participates_in CCO:I0015532 ! c6orf165-mdfi physical interaction relationship: participates_in CCO:I0015537 ! apg12l-mdfi physical interaction relationship: participates_in CCO:I0015541 ! cbx2-mdfi physical interaction relationship: participates_in CCO:I0015548 ! mdfi-znf417 physical interaction relationship: participates_in CCO:I0015550 ! mdfi-zfab physical interaction relationship: participates_in CCO:I0015553 ! mdfi-pvrl2 physical interaction relationship: participates_in CCO:I0015570 ! lrch4-mdfi physical interaction relationship: participates_in CCO:I0015589 ! mdfi-znf440 physical interaction relationship: participates_in CCO:I0015592 ! lmo3-mdfi physical interaction relationship: participates_in CCO:I0015643 ! mdfi-znf581 physical interaction relationship: participates_in CCO:I0015659 ! lasp1-mdfi physical interaction relationship: participates_in CCO:I0015667 ! mdfi-mgc13138 physical interaction relationship: participates_in CCO:I0015675 ! mdfi-theg physical interaction relationship: participates_in CCO:I0015696 ! cbfa2t2-mdfi physical interaction relationship: participates_in CCO:I0015699 ! mdfi-znf101 physical interaction relationship: participates_in CCO:I0015713 ! dnpep-mdfi physical interaction relationship: participates_in CCO:I0015719 ! ewsr1-mdfi physical interaction relationship: participates_in CCO:I0015743 ! mdfi-phlda1 physical interaction relationship: participates_in CCO:I0015747 ! c8orf48-mdfi physical interaction relationship: participates_in CCO:I0015770 ! crx-mdfi physical interaction relationship: participates_in CCO:I0015794 ! mdfi-tcfl1 physical interaction relationship: participates_in CCO:I0017551 ! mdfi-atn1 physical interaction relationship: participates_in CCO:I0017600 ! atn1-mdfi physical interaction relationship: participates_in CCO:I0017616 ! atxn7l2-mdfi physical interaction relationship: participates_in CCO:I0019423 ! zbtb25-mdf1 physical interaction relationship: participates_in CCO:I0019430 ! six1-mdf1 physical interaction relationship: participates_in CCO:I0020525 ! rp1_69m21_1-mdfi physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0005233 name: PSA1_HUMAN def: "Proteasome subunit alpha type-1" [UniProtKB:P25786] synonym: "30 kDa prosomal protein" EXACT [UniProtKB:P25786] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P25786] synonym: "Macropain subunit C2" EXACT [UniProtKB:P25786] synonym: "Multicatalytic endopeptidase complex subunit C2" EXACT [UniProtKB:P25786] synonym: "PROS-30" EXACT [UniProtKB:P25786] synonym: "Proteasome component C2" EXACT [UniProtKB:P25786] synonym: "Proteasome nu chain" EXACT [UniProtKB:P25786] xref: EMBL:AAA92734.1 xref: EMBL:AAH02577.1 xref: EMBL:AAH05932.1 xref: EMBL:AAH08472.1 xref: EMBL:AAH09576.1 xref: EMBL:AAH15105.1 xref: EMBL:AAH15356.1 xref: EMBL:AAH22372.1 xref: EMBL:BAA00656.1 xref: EMBL:CAA43961.1 xref: UniProtKB:P25786 xref: UniProtKB:Q9BRV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005385 ! PSMA1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000410 ! polysome relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0005799 ! ccnh-psma1 physical interaction relationship: participates_in CCO:I0005817 ! psma1-rad54b physical interaction relationship: participates_in CCO:I0005827 ! mcm6-psma1 physical interaction relationship: participates_in CCO:I0008219 ! dleu1-psma1 physical interaction relationship: participates_in CCO:I0008678 ! ndp52-psma1 physical interaction relationship: participates_in CCO:I0008680 ! psma1-tsc22d4 physical interaction relationship: participates_in CCO:I0008681 ! nmi-psma1 physical interaction relationship: participates_in CCO:I0008686 ! psma1-vim physical interaction relationship: participates_in CCO:I0008692 ! kctd17-psma1 physical interaction relationship: participates_in CCO:I0008694 ! krt15-psma1 physical interaction relationship: participates_in CCO:I0008711 ! traf6-psma1 physical interaction relationship: participates_in CCO:I0008724 ! alpha1-alpha2 physical interaction relationship: participates_in CCO:I0008725 ! alpha1-alpha7 physical interaction relationship: participates_in CCO:I0008726 ! alpha1-beta2 physical interaction relationship: participates_in CCO:I0008727 ! alpha1-beta2i physical interaction relationship: participates_in CCO:I0008728 ! alpha2-alpha1 physical interaction relationship: participates_in CCO:I0008737 ! alpha7-alpha1 physical interaction relationship: participates_in CCO:I0008761 ! psma1-coil physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0013618 ! PSA1_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005234 name: NONO_HUMAN def: "Non-POU domain-containing octamer-binding protein" [UniProtKB:Q15233] synonym: "54 kDa nuclear RNA- and DNA-binding protein" EXACT [UniProtKB:Q15233] synonym: "55 kDa nuclear protein" EXACT [UniProtKB:Q15233] synonym: "DNA-binding p52/p100 complex, 52 kDa subunit" EXACT [UniProtKB:Q15233] synonym: "NMT55" EXACT [UniProtKB:Q15233] synonym: "NonO protein" EXACT [UniProtKB:Q15233] synonym: "p54(nrb)" EXACT [UniProtKB:Q15233] synonym: "p54nrb" EXACT [UniProtKB:Q15233] xref: EMBL:AAA03427.1 xref: EMBL:AAC37578.1 xref: EMBL:AAC51852.1 xref: EMBL:AAH02364.1 xref: EMBL:AAH03129.1 xref: EMBL:AAH12141.1 xref: EMBL:AAH28299.1 xref: EMBL:AAH69616.1 xref: EMBL:AAH69639.1 xref: EMBL:CAA72157.1 xref: EMBL:CAG33042.1 xref: UniProtKB:O00201 xref: UniProtKB:P30807 xref: UniProtKB:Q12786 xref: UniProtKB:Q15233 xref: UniProtKB:Q9BQC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005207 ! NONO_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005803 ! mad1l1-nono physical interaction relationship: participates_in CCO:I0005915 ! nono-pin1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015334 ! nono-plekhf2 physical interaction relationship: participates_in CCO:I0015563 ! nono-znrd1 physical interaction relationship: participates_in CCO:I0015593 ! nono-nono physical interaction relationship: participates_in CCO:I0016876 ! relb-nono physical interaction relationship: participates_in CCO:I0016973 ! tbk1-nono physical interaction relationship: participates_in CCO:I0017103 ! traf1-nono physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013236 ! NONO_HUMAN-Phosphothreonine428 relationship: transforms_into CCO:B0013237 ! NONO_HUMAN-Phosphothreonine450 relationship: transforms_into CCO:B0048338 ! NONO_HUMAN-Phosphoserine147 [Term] id: CCO:B0005235 name: HNRPK_HUMAN def: "Heterogeneous nuclear ribonucleoprotein K" [UniProtKB:P61978] synonym: "hnRNP K" EXACT [UniProtKB:P61978] synonym: "Transformation up-regulated nuclear protein" EXACT [UniProtKB:P61978] synonym: "TUNP" EXACT [UniProtKB:P61978] xref: EMBL:AAB20770.1 xref: EMBL:AAH00355.1 xref: EMBL:AAH14980.1 xref: EMBL:BAD92799.1 xref: EMBL:CAA51267.1 xref: EMBL:CAI16020.1 xref: EMBL:EAW62675.1 xref: UniProtKB:P61978 xref: UniProtKB:Q07244 xref: UniProtKB:Q15671 xref: UniProtKB:Q59F98 xref: UniProtKB:Q5T6W4 xref: UniProtKB:Q60577 xref: UniProtKB:Q922Y7 xref: UniProtKB:Q96J62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014354 ! HNRNPK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005804 ! hnrpk-rbm7 physical interaction relationship: participates_in CCO:I0005929 ! hnrpk-ube2i physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007650 ! gfi1b-hnrpk physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0014979 ! flj11016-hnrpk physical interaction relationship: participates_in CCO:I0015090 ! grap2-hnrpk physical interaction relationship: participates_in CCO:I0015095 ! hnrpk-hnrpk physical interaction relationship: participates_in CCO:I0015194 ! hnrpk-matr3 physical interaction relationship: participates_in CCO:I0015287 ! hnrpk-mgc10433 physical interaction relationship: participates_in CCO:I0015457 ! hnrpk-npdc1 physical interaction relationship: participates_in CCO:I0015552 ! hnrpk-khdrbs3 physical interaction relationship: participates_in CCO:I0015689 ! hnrpk-rbmx physical interaction relationship: participates_in CCO:I0015724 ! hnrpk-hqk physical interaction relationship: participates_in CCO:I0015758 ! hnrpk-scam_1 physical interaction relationship: participates_in CCO:I0015836 ! hnrpk-nck2 physical interaction relationship: participates_in CCO:I0018429 ! hck-hnrpk-1 physical interaction relationship: participates_in CCO:I0019152 ! pcbp1-hnrpk physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012244 ! HNRPK_HUMAN-Phosphothreonine3 relationship: transforms_into CCO:B0012245 ! HNRPK_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0012246 ! HNRPK_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0012247 ! HNRPK_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0012248 ! HNRPK_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0012249 ! HNRPK_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0012250 ! HNRPK_HUMAN-Omega-N-methylated arginine296 relationship: transforms_into CCO:B0012251 ! HNRPK_HUMAN-Omega-N-methylated arginine299 relationship: transforms_into CCO:B0012252 ! HNRPK_HUMAN-Phosphoserine379 relationship: transforms_into CCO:B0041307 ! HNRPK_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005236 name: Q8TAX5_HUMAN def: "AFF4 protein" [UniProtKB:Q8TAX5] xref: EMBL:AAH25700.1 xref: UniProtKB:Q8TAX5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006029 ! AFF4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005805 ! aff4-siah1 physical interaction relationship: participates_in CCO:I0015182 ! aff4-traf2 physical interaction [Term] id: CCO:B0005237 name: RB22A_HUMAN def: "Ras-related protein Rab-22A" [UniProtKB:Q9UL26] synonym: "Rab-22" EXACT [UniProtKB:Q9UL26] xref: EMBL:AAF00047.2 xref: EMBL:AAH15710.1 xref: EMBL:AAH63457.1 xref: EMBL:AAL75941.1 xref: EMBL:AAP35695.1 xref: EMBL:CAC10538.1 xref: EMBL:CAC15020.1 xref: UniProtKB:Q8TF12 xref: UniProtKB:Q9H4E6 xref: UniProtKB:Q9UL26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005436 ! RAB22A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005807 ! dip13b-rab22a physical interaction relationship: participates_in CCO:I0018477 ! eea1-rab22a-1 physical interaction relationship: participates_in CCO:I0018478 ! eea1-rab22a-2 physical interaction relationship: participates_in CCO:I0018771 ! eea1-rab22a-3 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0005239 name: HNRPC_HUMAN def: "Heterogeneous nuclear ribonucleoproteins C1/C2" [UniProtKB:P07910] synonym: "hnRNP C1 / hnRNP C2" EXACT [UniProtKB:P07910] xref: EMBL:AAA36576.1 xref: EMBL:AAA52680.1 xref: EMBL:AAH03394.1 xref: EMBL:AAH07052.1 xref: EMBL:AAH08364.1 xref: EMBL:AAH08423.1 xref: EMBL:AAH66932.1 xref: EMBL:AAH89438.1 xref: EMBL:AAI03759.1 xref: EMBL:AAI08659.1 xref: EMBL:BAD92764.1 xref: EMBL:BAD97237.1 xref: EMBL:CAD61934.1 xref: EMBL:CAD62300.1 xref: EMBL:CAD62326.1 xref: UniProtKB:P07910 xref: UniProtKB:P22628 xref: UniProtKB:Q53EX2 xref: UniProtKB:Q59FD3 xref: UniProtKB:Q5FWE8 xref: UniProtKB:Q86SF8 xref: UniProtKB:Q86U45 xref: UniProtKB:Q96HK7 xref: UniProtKB:Q96HM4 xref: UniProtKB:Q96IY5 xref: UniProtKB:Q9BTS3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006360 ! HNRNPC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005809 ! hnrpc-kras physical interaction relationship: participates_in CCO:I0005874 ! hnrpc-pin1 physical interaction relationship: participates_in CCO:I0005920 ! hnrpc-ube2i physical interaction relationship: participates_in CCO:I0007093 ! srpk1-top2a-1 physical interaction relationship: participates_in CCO:I0007250 ! srpk1-top2a-2 physical interaction relationship: participates_in CCO:I0015466 ! hnrpc-znf581 physical interaction relationship: participates_in CCO:I0015760 ! hnrpc-lmo3 physical interaction relationship: participates_in CCO:I0016822 ! nfkb2-hnrpc physical interaction relationship: transforms_into CCO:B0012212 ! HNRPC_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0012213 ! HNRPC_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0012214 ! HNRPC_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0012215 ! HNRPC_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0012216 ! HNRPC_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0012217 ! HNRPC_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0012218 ! HNRPC_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0012219 ! HNRPC_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0012220 ! HNRPC_HUMAN-Phosphoserine260 relationship: transforms_into CCO:B0012221 ! HNRPC_HUMAN-Phosphoserine299 relationship: transforms_into CCO:B0041144 ! HNRPC_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0048277 ! HNRPC_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0066862 ! HNRPC_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0066863 ! HNRPC_HUMAN-Phosphoserine121 [Term] id: CCO:B0005240 name: RIBC2_HUMAN def: "RIB43A-like with coiled-coils protein 2" [UniProtKB:Q9H4K1] xref: EMBL:AAH03024.1 xref: EMBL:AAH09904.1 xref: EMBL:CAB43258.1 xref: EMBL:CAC09526.1 xref: EMBL:CAG30324.1 xref: EMBL:CAG33679.1 xref: EMBL:CAI18929.1 xref: UniProtKB:Q6ICD0 xref: UniProtKB:Q9H4K1 xref: UniProtKB:Q9Y413 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005488 ! RIBC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005811 ! atrip-ribc2 physical interaction relationship: participates_in CCO:I0005882 ! rad54b-ribc2 physical interaction relationship: participates_in CCO:I0014959 ! ribc2-trim23 physical interaction relationship: participates_in CCO:I0015372 ! ribc2-traf2 physical interaction [Term] id: CCO:B0005241 name: GORS2_HUMAN def: "Golgi reassembly-stacking protein 2" [UniProtKB:Q9H8Y8] synonym: "Golgi phosphoprotein 6" EXACT [UniProtKB:Q9H8Y8] synonym: "Golgi reassembly-stacking protein of 55 kDa" EXACT [UniProtKB:Q9H8Y8] synonym: "GOLPH6" EXACT [UniProtKB:Q9H8Y8] synonym: "GRASP55" EXACT [UniProtKB:Q9H8Y8] synonym: "GRS2" EXACT [UniProtKB:Q9H8Y8] synonym: "p59" EXACT [UniProtKB:Q9H8Y8] xref: EMBL:AAH07770.1 xref: EMBL:BAB14395.1 xref: EMBL:BAB14459.1 xref: EMBL:BAB55054.1 xref: EMBL:CAB55919.1 xref: UniProtKB:Q96I74 xref: UniProtKB:Q96K84 xref: UniProtKB:Q9H8Y8 xref: UniProtKB:Q9H946 xref: UniProtKB:Q9UFW4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004717 ! GORASP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005813 ! gorasp2-rad54b physical interaction relationship: participates_in CCO:I0005832 ! gorasp2-nme1 physical interaction relationship: participates_in CCO:I0014951 ! gorasp2-tsc22d4 physical interaction relationship: participates_in CCO:I0015146 ! gorasp2-mif physical interaction relationship: participates_in CCO:I0015337 ! gorasp2-traf2 physical interaction relationship: participates_in CCO:I0015603 ! gorasp2-pcbd1 physical interaction relationship: participates_in CCO:I0015745 ! gorasp2-nup62 physical interaction relationship: transforms_into CCO:B0011957 ! GORS2_HUMAN-Omega-N-methylated arginine30 relationship: transforms_into CCO:B0011958 ! GORS2_HUMAN-Omega-N-methylated arginine47 relationship: transforms_into CCO:B0011959 ! GORS2_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0011960 ! GORS2_HUMAN-Phosphothreonine222 relationship: transforms_into CCO:B0011961 ! GORS2_HUMAN-Phosphothreonine225 relationship: transforms_into CCO:B0011962 ! GORS2_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0011963 ! GORS2_HUMAN-Phosphothreonine415 relationship: transforms_into CCO:B0011964 ! GORS2_HUMAN-Phosphoserine451 relationship: transforms_into CCO:B0066520 ! GORS2_HUMAN-Phosphothreonine433 relationship: transforms_into CCO:B0066521 ! GORS2_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0066522 ! GORS2_HUMAN-Phosphoserine449 [Term] id: CCO:B0005242 name: Q8IUU6_HUMAN def: "IL16 protein" [UniProtKB:Q8IUU6] xref: EMBL:AAH40272.1 xref: UniProtKB:Q8IUU6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006017 ! IL16_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005815 ! il16-sssca1 physical interaction [Term] id: CCO:B0005243 name: ARD1A_HUMAN def: "N-terminal acetyltransferase complex ARD1 subunit homolog A" [UniProtKB:P41227] synonym: "EC 2.3.1.-" EXACT [UniProtKB:P41227] synonym: "EC 2.3.1.88" EXACT [UniProtKB:P41227] xref: EMBL:AAH00308.1 xref: EMBL:AAH19312.1 xref: EMBL:CAA54691.1 xref: UniProtKB:P41227 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004088 ! ARD1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005818 ! ard1-cdc25a physical interaction relationship: transforms_into CCO:B0010587 ! ARD1A_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0010588 ! ARD1A_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0065697 ! ARD1A_HUMAN-Phosphoserine205 [Term] id: CCO:B0005244 name: CEP76_HUMAN def: "Centrosomal protein of 76 kDa" [UniProtKB:Q8TAP6] synonym: "Cep76" EXACT [UniProtKB:Q8TAP6] xref: EMBL:AAH26307.1 xref: EMBL:BAB14123.1 xref: EMBL:CAH56252.1 xref: UniProtKB:Q658N5 xref: UniProtKB:Q8TAP6 xref: UniProtKB:Q9H9U7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004331 ! CEP76_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:I0005820 ! ccnk-cep76 physical interaction relationship: transforms_into CCO:B0064298 ! CEP76_HUMAN-Phosphoserine83 [Term] id: CCO:B0005246 name: RPAC1_HUMAN def: "DNA-directed RNA polymerases I and III subunit RPAC1" [UniProtKB:O15160] synonym: "AC40" EXACT [UniProtKB:O15160] synonym: "DNA-directed RNA polymerase I subunit C" EXACT [UniProtKB:O15160] synonym: "DNA-directed RNA polymerases I and III 40 kDa polypeptide" EXACT [UniProtKB:O15160] synonym: "RNA polymerases I and III subunit AC1" EXACT [UniProtKB:O15160] synonym: "RPA39" EXACT [UniProtKB:O15160] synonym: "RPA40" EXACT [UniProtKB:O15160] synonym: "RPC40" EXACT [UniProtKB:O15160] xref: EMBL:AAC14354.1 xref: EMBL:AAC39892.1 xref: EMBL:AAH08863.1 xref: EMBL:CAI42629.1 xref: UniProtKB:O15160 xref: UniProtKB:O75395 xref: UniProtKB:Q5JTE3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005525 ! POLR1C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005823 ! nme1-polr1c physical interaction relationship: participates_in CCO:I0017183 ! nfkbib-polr1c physical interaction relationship: transforms_into CCO:B0013930 ! RPAC1_HUMAN-Phosphotyrosine33 [Term] id: CCO:B0005247 name: CHST1_HUMAN def: "Carbohydrate sulfotransferase 1" [UniProtKB:O43916] synonym: "EC 2.8.2.21" EXACT [UniProtKB:O43916] synonym: "Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1" EXACT [UniProtKB:O43916] synonym: "GST-1" EXACT [UniProtKB:O43916] synonym: "Keratan sulfate Gal-6 sulfotransferase" EXACT [UniProtKB:O43916] synonym: "KS6ST" EXACT [UniProtKB:O43916] synonym: "KSGal6ST" EXACT [UniProtKB:O43916] synonym: "KSST" EXACT [UniProtKB:O43916] xref: EMBL:AAC28776.1 xref: EMBL:AAD19878.1 xref: EMBL:AAH22567.1 xref: EMBL:AAH28235.1 xref: EMBL:AAP88041.1 xref: EMBL:BAA24840.1 xref: UniProtKB:O43916 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004352 ! CHST1_human relationship: has_function CCO:F0001748 ! sulfotransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006075 ! keratan sulfotransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0005824 ! chst1-sfn physical interaction [Term] id: CCO:B0005248 name: RCN3_HUMAN def: "Reticulocalbin-3 precursor" [UniProtKB:Q96D15] synonym: "EF-hand calcium-binding protein RLP49" EXACT [UniProtKB:Q96D15] xref: EMBL:AAG09692.1 xref: EMBL:AAH13436.1 xref: EMBL:AAO43054.1 xref: EMBL:AAQ88789.1 xref: UniProtKB:Q96D15 xref: UniProtKB:Q9HBZ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005458 ! RCN3_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: participates_in CCO:I0005826 ! rcn3-sufu physical interaction relationship: participates_in CCO:I0007889 ! sufu-rcn3 physical interaction [Term] id: CCO:B0005249 name: TRI37_HUMAN def: "Tripartite motif-containing protein 37" [UniProtKB:O94972] synonym: "Mulibrey nanism protein" EXACT [UniProtKB:O94972] xref: EMBL:AAH36012.1 xref: EMBL:AAL36460.1 xref: EMBL:BAA74921.1 xref: EMBL:CAD97922.1 xref: UniProtKB:O94972 xref: UniProtKB:Q7Z3E6 xref: UniProtKB:Q8IYF7 xref: UniProtKB:Q8WYF7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005830 ! TRIM37_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005829 ! dlg7-trim37 physical interaction relationship: participates_in CCO:I0005924 ! pbk-trim37 physical interaction relationship: participates_in CCO:I0015027 ! tceb3b-trim37 physical interaction relationship: participates_in CCO:I0015100 ! drr1-trim37 physical interaction relationship: participates_in CCO:I0015246 ! rhpn1-trim37 physical interaction relationship: participates_in CCO:I0015329 ! trim37-znf655 physical interaction relationship: participates_in CCO:I0015444 ! pnkp-trim37 physical interaction relationship: participates_in CCO:I0015584 ! trim37-znf417 physical interaction relationship: participates_in CCO:I0015639 ! ewsr1-trim37 physical interaction relationship: participates_in CCO:I0017598 ! aptx-trim37-1 physical interaction relationship: participates_in CCO:I0018913 ! aptx-trim37 physical interaction relationship: transforms_into CCO:B0014534 ! TRI37_HUMAN-Phosphoserine771 relationship: transforms_into CCO:B0014535 ! TRI37_HUMAN-Phosphoserine773 [Term] id: CCO:B0005250 name: MYOZ2_HUMAN def: "Myozenin-2" [UniProtKB:Q9NPC6] synonym: "Calsarcin-1" EXACT [UniProtKB:Q9NPC6] synonym: "FATZ-related protein 2" EXACT [UniProtKB:Q9NPC6] xref: EMBL:AAC19160.1 xref: EMBL:AAF63623.1 xref: EMBL:AAG13932.1 xref: EMBL:AAG38938.1 xref: EMBL:AAH05195.1 xref: EMBL:AAH17402.1 xref: EMBL:AAH20932.1 xref: EMBL:AAP35878.1 xref: EMBL:CAB92965.1 xref: UniProtKB:O43415 xref: UniProtKB:Q9HB92 xref: UniProtKB:Q9NPC6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005149 ! MYOZ2_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004400 ! protein phosphatase 2B binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000933 ! sarcomere relationship: located_in CCO:C0000934 ! Z disc relationship: participates_in CCO:I0005830 ! actn4-myoz2 physical interaction relationship: participates_in CCO:I0015271 ! ewsr1-myoz2 physical interaction relationship: transforms_into CCO:B0013069 ! MYOZ2_HUMAN-Phosphothreonine111 [Term] id: CCO:B0005251 name: SCNM1_HUMAN def: "Sodium channel modifier 1" [UniProtKB:Q9BWG6] xref: EMBL:AAH00264.1 xref: EMBL:BAB71149.1 xref: EMBL:CAI16381.1 xref: EMBL:CAI16382.1 xref: UniProtKB:Q5JR74 xref: UniProtKB:Q9BWG6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005574 ! SCNM1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005833 ! mcm6-scnm1 physical interaction relationship: transforms_into CCO:B0048388 ! SCNM1_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0070364 ! SCNM1_HUMAN-Phosphoserine144 relationship: transforms_into CCO:B0070365 ! SCNM1_HUMAN-Phosphoserine219 [Term] id: CCO:B0005252 name: ZC11A_HUMAN def: "Zinc finger CCCH domain-containing protein 11A" [UniProtKB:O75152] xref: EMBL:AAH14268.1 xref: EMBL:AAH48271.1 xref: EMBL:BAA31638.2 xref: EMBL:CAH10525.1 xref: EMBL:CAH10530.1 xref: EMBL:CAH10553.1 xref: EMBL:CAH10566.1 xref: UniProtKB:O75152 xref: UniProtKB:Q6AHY4 xref: UniProtKB:Q6AHY9 xref: UniProtKB:Q6AW79 xref: UniProtKB:Q6AWA1 xref: UniProtKB:Q6PJK4 xref: UniProtKB:Q86XZ7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005953 ! ZC3H11A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005834 ! mlh1-zc3h11a physical interaction relationship: transforms_into CCO:B0014731 ! ZC11A_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0014732 ! ZC11A_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0014733 ! ZC11A_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0014734 ! ZC11A_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0014735 ! ZC11A_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0014736 ! ZC11A_HUMAN-Phosphoserine758 relationship: transforms_into CCO:B0014737 ! ZC11A_HUMAN-Phosphoserine759 relationship: transforms_into CCO:B0014738 ! ZC11A_HUMAN-Phosphoserine761 relationship: transforms_into CCO:B0014739 ! ZC11A_HUMAN-Phosphothreonine762 [Term] id: CCO:B0005253 name: TCPG_HUMAN def: "T-complex protein 1 subunit gamma" [UniProtKB:P49368] synonym: "CCT-gamma" EXACT [UniProtKB:P49368] synonym: "hTRiC5" EXACT [UniProtKB:P49368] synonym: "TCP-1-gamma" EXACT [UniProtKB:P49368] xref: EMBL:AAC50068.1 xref: EMBL:AAH06501.3 xref: EMBL:AAH08019.1 xref: EMBL:CAA52808.1 xref: EMBL:CAI14167.1 xref: EMBL:CAI46192.1 xref: UniProtKB:P49368 xref: UniProtKB:Q5SZY1 xref: UniProtKB:Q9BR64 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005753 ! CCT3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0005836 ! cct3-sssca1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0016086 ! cct3-g22p1 physical interaction relationship: participates_in CCO:I0016275 ! raf1-cct3 physical interaction relationship: participates_in CCO:I0016622 ! map3k1-cct3 physical interaction relationship: participates_in CCO:I0016715 ! map3k3-cct3 physical interaction relationship: participates_in CCO:I0016969 ! tbk1-cct3 physical interaction relationship: participates_in CCO:I0017683 ! raf1-cct3-2 physical interaction relationship: participates_in CCO:I0019377 ! raf1-cct3-1 physical interaction relationship: participates_in CCO:I0020270 ! cct3-eif2b2 physical interaction relationship: transforms_into CCO:B0014324 ! TCPG_HUMAN-Phosphothreonine254 relationship: transforms_into CCO:B0048408 ! TCPG_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005254 name: K1683_HUMAN def: "Uncharacterized protein KIAA1683" [UniProtKB:Q9H0B3] xref: EMBL:AAH34327.1 xref: EMBL:BAB21774.1 xref: EMBL:BAB71500.1 xref: EMBL:CAB66801.1 xref: UniProtKB:Q8N4G8 xref: UniProtKB:Q96M14 xref: UniProtKB:Q9C0I0 xref: UniProtKB:Q9H0B3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004919 ! KIAA1683_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0005837 ! calm1-kiaa1683 physical interaction relationship: participates_in CCO:I0015741 ! kiaa1683-trip6 physical interaction relationship: transforms_into CCO:B0012454 ! K1683_HUMAN-Phosphotyrosine302 relationship: transforms_into CCO:B0012455 ! K1683_HUMAN-Phosphothreonine307 relationship: transforms_into CCO:B0012456 ! K1683_HUMAN-Phosphothreonine314 relationship: transforms_into CCO:B0012457 ! K1683_HUMAN-Phosphoserine367 [Term] id: CCO:B0005255 name: EXOC8_HUMAN def: "Exocyst complex component 8" [UniProtKB:Q8IYI6] synonym: "Exocyst complex 84 kDa subunit" EXACT [UniProtKB:Q8IYI6] xref: EMBL:AAH35763.2 xref: EMBL:CAI23095.1 xref: UniProtKB:Q5TE82 xref: UniProtKB:Q8IYI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004596 ! EXOC8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005839 ! exoc8-krt18 physical interaction relationship: participates_in CCO:I0015034 ! exoc8-tada2l physical interaction relationship: participates_in CCO:I0015227 ! exoc8-hgs physical interaction relationship: transforms_into CCO:B0011809 ! EXOC8_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0065183 ! EXOC8_HUMAN-Phosphothreonine142 [Term] id: CCO:B0005256 name: HNRPG_HUMAN def: "Heterogeneous nuclear ribonucleoprotein G" [UniProtKB:P38159] synonym: "Glycoprotein p43" EXACT [UniProtKB:P38159] synonym: "hnRNP G" EXACT [UniProtKB:P38159] synonym: "RNA-binding motif protein, X chromosome" EXACT [UniProtKB:P38159] xref: EMBL:AAH06550.1 xref: EMBL:AAH07435.1 xref: EMBL:AAK58567.1 xref: EMBL:AAR28036.1 xref: EMBL:CAA80599.1 xref: EMBL:CAI39448.1 xref: UniProtKB:P38159 xref: UniProtKB:Q5JQ67 xref: UniProtKB:Q969R3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004820 ! RBMX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005840 ! rbm7-rbmx physical interaction relationship: participates_in CCO:I0015111 ! khdrbs3-rbmx physical interaction relationship: participates_in CCO:I0015689 ! hnrpk-rbmx physical interaction relationship: transforms_into CCO:B0012234 ! HNRPG_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0012235 ! HNRPG_HUMAN-N-acetylvaline2 relationship: transforms_into CCO:B0012236 ! HNRPG_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0012237 ! HNRPG_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0012238 ! HNRPG_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0012239 ! HNRPG_HUMAN-Omega-N-methylated arginine185 relationship: transforms_into CCO:B0012240 ! HNRPG_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0012241 ! HNRPG_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0012242 ! HNRPG_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0012243 ! HNRPG_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0048278 ! HNRPG_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0048279 ! HNRPG_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0066865 ! HNRPG_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0066866 ! HNRPG_HUMAN-Phosphotyrosine327 relationship: transforms_into CCO:B0066867 ! HNRPG_HUMAN-Phosphoserine329 [Term] id: CCO:B0005257 name: SAMD3_HUMAN def: "Sterile alpha motif domain-containing protein 3" [UniProtKB:Q8N6K7] xref: EMBL:AAH29851.1 xref: EMBL:AAI19758.1 xref: EMBL:AAI19759.1 xref: EMBL:BAC03644.1 xref: EMBL:BAC03765.1 xref: EMBL:CAI95328.1 xref: UniProtKB:Q4VXD8 xref: UniProtKB:Q8N6K7 xref: UniProtKB:Q8NAY1 xref: UniProtKB:Q8NB96 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005561 ! SAMD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005841 ! fancg-samd3 physical interaction [Term] id: CCO:B0005258 name: DTBP1_HUMAN def: "Dysbindin" [UniProtKB:Q96EV8] synonym: "Dystrobrevin-binding protein 1" EXACT [UniProtKB:Q96EV8] synonym: "Hermansky-Pudlak syndrome 7 protein homolog" EXACT [UniProtKB:Q96EV8] synonym: "Hps7-like protein" EXACT [UniProtKB:Q96EV8] xref: EMBL:AAG43145.1 xref: EMBL:AAH11912.1 xref: EMBL:AAL46636.1 xref: EMBL:AAP91870.1 xref: EMBL:BAB70770.1 xref: EMBL:CAB66572.1 xref: EMBL:CAI21976.1 xref: EMBL:CAI21977.1 xref: EMBL:CAI42339.1 xref: EMBL:CAI42340.1 xref: UniProtKB:Q5THY3 xref: UniProtKB:Q5THY4 xref: UniProtKB:Q96EV8 xref: UniProtKB:Q96NV2 xref: UniProtKB:Q9H0U2 xref: UniProtKB:Q9H3J5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004515 ! DTNBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005842 ! ccnd3-dtnbp1 physical interaction relationship: participates_in CCO:I0006570 ! dtnbp1-ccna2 physical interaction relationship: participates_in CCO:I0006581 ! dtnbp1-bpag1 physical interaction relationship: participates_in CCO:I0006593 ! dtnbp1-macf1 physical interaction relationship: participates_in CCO:I0008760 ! dtnbp1-psme3 physical interaction relationship: participates_in CCO:I0015028 ! abi3-dtnbp1 physical interaction relationship: participates_in CCO:I0015210 ! arfip2-dtnbp1 physical interaction relationship: participates_in CCO:I0017424 ! dtnbp1-brf1 physical interaction relationship: participates_in CCO:I0017444 ! dtnbp1-rab11a physical interaction relationship: participates_in CCO:I0017484 ! dtnbp1-znf490 physical interaction relationship: transforms_into CCO:B0064889 ! DTBP1_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0064890 ! DTBP1_HUMAN-Phosphoserine321 [Term] id: CCO:B0005259 name: VTA1_HUMAN def: "Vacuolar protein sorting-associated protein VTA1 homolog" [UniProtKB:Q9NP79] synonym: "Dopamine-responsive protein DRG-1" EXACT [UniProtKB:Q9NP79] xref: EMBL:AAF36148.1 xref: EMBL:AAF76210.1 xref: EMBL:AAG43125.1 xref: EMBL:AAH05937.1 xref: EMBL:AAH06989.1 xref: EMBL:AAH22536.1 xref: EMBL:BAA90909.1 xref: EMBL:CAB66619.1 xref: EMBL:CAG33488.1 xref: EMBL:CAI21072.1 xref: UniProtKB:Q5TGM1 xref: UniProtKB:Q6IAE8 xref: UniProtKB:Q9H0R2 xref: UniProtKB:Q9H3K9 xref: UniProtKB:Q9NP79 xref: UniProtKB:Q9P0Q0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005908 ! VTA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005844 ! c6orf55-sssca1 physical interaction relationship: participates_in CCO:I0005885 ! c6orf55-cdk4 physical interaction relationship: participates_in CCO:I0015170 ! c6orf55-kctd13 physical interaction relationship: participates_in CCO:I0015447 ! c6orf55-mbip physical interaction relationship: transforms_into CCO:B0071820 ! VTA1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005260 name: NIF3L_HUMAN def: "NIF3-like protein 1" [UniProtKB:Q9GZT8] synonym: "Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein" EXACT [UniProtKB:Q9GZT8] xref: EMBL:AAG14952.1 xref: EMBL:AAG43131.1 xref: EMBL:AAG44846.1 xref: EMBL:AAH07654.1 xref: EMBL:AAY14724.1 xref: EMBL:BAB14551.1 xref: EMBL:BAB32499.1 xref: EMBL:EAW70224.1 xref: UniProtKB:Q53TX4 xref: UniProtKB:Q9GZT8 xref: UniProtKB:Q9H2D2 xref: UniProtKB:Q9HC18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005194 ! NIF3L1_human relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005846 ! mapre2-nif3l1 physical interaction relationship: participates_in CCO:I0014996 ! hhgp-nif3l1 physical interaction relationship: participates_in CCO:I0015018 ! nif3l1-vim physical interaction relationship: participates_in CCO:I0015024 ! dhps-nif3l1 physical interaction relationship: participates_in CCO:I0015063 ! flj10094-nif3l1 physical interaction relationship: participates_in CCO:I0015071 ! magea11-nif3l1 physical interaction relationship: participates_in CCO:I0015094 ! nif3l1-zbed1x physical interaction relationship: participates_in CCO:I0015144 ! nif3l1-traf2 physical interaction relationship: participates_in CCO:I0015156 ! nif3l1-nif3l1 physical interaction relationship: participates_in CCO:I0015202 ! cpsf5-nif3l1 physical interaction relationship: participates_in CCO:I0015228 ! gnmt-nif3l1 physical interaction relationship: participates_in CCO:I0015296 ! nif3l1-tifa physical interaction relationship: participates_in CCO:I0015313 ! nif3l1-rpia physical interaction relationship: participates_in CCO:I0015320 ! kctd17-nif3l1 physical interaction relationship: participates_in CCO:I0015423 ! nif3l1-trim21 physical interaction relationship: participates_in CCO:I0015471 ! nif3l1-nol3 physical interaction relationship: participates_in CCO:I0015572 ! nif3l1-s100a1 physical interaction relationship: participates_in CCO:I0015623 ! nif3l1-rabac1 physical interaction relationship: participates_in CCO:I0015652 ! nif3l1-snf8 physical interaction relationship: participates_in CCO:I0015674 ! mgc2749-nif3l1 physical interaction relationship: participates_in CCO:I0015687 ! nif3l1-xtp3tpa physical interaction relationship: participates_in CCO:I0015695 ! nif3l1-tsc22d4 physical interaction relationship: participates_in CCO:I0015703 ! nif3l1-pcbd1 physical interaction relationship: participates_in CCO:I0015720 ! krt15-nif3l1 physical interaction relationship: participates_in CCO:I0015753 ! cutc-nif3l1 physical interaction relationship: participates_in CCO:I0015780 ! dctd-nif3l1 physical interaction relationship: participates_in CCO:I0017575 ! nif3l1-coil physical interaction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0005261 name: Q96A78_HUMAN def: "TBL3 protein" [UniProtKB:Q96A78] synonym: "Transducin (Beta)-like 3" EXACT [UniProtKB:Q96A78] synonym: "Transducin (Beta)-like 3, isoform CRA_e" EXACT [UniProtKB:Q96A78] xref: EMBL:AAH10231.1 xref: EMBL:AAH14007.1 xref: EMBL:EAW85589.1 xref: UniProtKB:Q96A78 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005743 ! TBL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005847 ! sfn-tbl3 physical interaction [Term] id: CCO:B0005262 name: CJ119_HUMAN def: "UPF0557 protein C10orf119" [UniProtKB:Q9BTE3] xref: EMBL:AAH00935.1 xref: EMBL:AAH04183.1 xref: EMBL:AAH07219.1 xref: EMBL:BAB14427.1 xref: EMBL:CAG33580.1 xref: UniProtKB:Q6IA56 xref: UniProtKB:Q9BTE3 xref: UniProtKB:Q9BVT9 xref: UniProtKB:Q9H916 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004357 ! C10orf119_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005849 ! c10orf119-ddit3 physical interaction relationship: transforms_into CCO:B0011225 ! CJ119_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0011226 ! CJ119_HUMAN-Phosphothreonine160 relationship: transforms_into CCO:B0064361 ! CJ119_HUMAN-Phosphoserine298 [Term] id: CCO:B0005263 name: ZN567_HUMAN def: "Zinc finger protein 567" [UniProtKB:Q8N184] xref: EMBL:AAH33849.2 xref: EMBL:CAE45826.1 xref: UniProtKB:Q6N044 xref: UniProtKB:Q8N184 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005963 ! ZNF567_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005850 ! mltk-znf567 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005264 name: PHC1_HUMAN def: "Polyhomeotic-like protein 1" [UniProtKB:P78364] synonym: "Early development regulatory protein 1" EXACT [UniProtKB:P78364] synonym: "hPH1" EXACT [UniProtKB:P78364] xref: EMBL:AAC51169.1 xref: EMBL:AAH02871.2 xref: EMBL:AAH17748.1 xref: UniProtKB:P78364 xref: UniProtKB:Q8WVM3 xref: UniProtKB:Q9BU63 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005307 ! PHC1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005851 ! phc1-ube2i physical interaction relationship: participates_in CCO:I0015336 ! phc1-sfmbt1 physical interaction relationship: transforms_into CCO:B0069247 ! PHC1_HUMAN-Phosphotyrosine32 [Term] id: CCO:B0005265 name: DYRK2_HUMAN def: "Dual specificity tyrosine-phosphorylation-regulated kinase 2" [UniProtKB:Q92630] synonym: "EC 2.7.12.1" EXACT [UniProtKB:Q92630] xref: EMBL:AAH05809.1 xref: EMBL:AAH06375.1 xref: EMBL:CAA70418.1 xref: EMBL:CAA73885.1 xref: UniProtKB:Q92630 xref: UniProtKB:Q9BRB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004529 ! DYRK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005852 ! dyrk2-rad54b physical interaction relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis relationship: participates_in CCO:P0002522 ! positive regulation of glycogen biosynthetic process relationship: transforms_into CCO:B0064910 ! DYRK2_HUMAN-Phosphotyrosine382 [Term] id: CCO:B0005266 name: MAGAC_HUMAN def: "Melanoma-associated antigen 12" [UniProtKB:P43365] synonym: "Cancer/testis antigen 1.12" EXACT [UniProtKB:P43365] synonym: "CT1.12" EXACT [UniProtKB:P43365] synonym: "MAGE-12 antigen" EXACT [UniProtKB:P43365] synonym: "MAGE12F antigen" EXACT [UniProtKB:P43365] xref: EMBL:AAA19023.1 xref: EMBL:AAH03408.1 xref: EMBL:AAP35772.1 xref: UniProtKB:P43365 xref: UniProtKB:Q9NSD3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005017 ! MAGEA12_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0005853 ! magea12-stat5a physical interaction [Term] id: CCO:B0005267 name: FRMD6_HUMAN def: "FERM domain-containing protein 6" [UniProtKB:Q96NE9] synonym: "Willin" EXACT [UniProtKB:Q96NE9] xref: EMBL:AAH20521.1 xref: EMBL:AAH29870.1 xref: EMBL:BAB70950.1 xref: EMBL:CAD61902.1 xref: EMBL:CAI46062.1 xref: UniProtKB:Q5HYF2 xref: UniProtKB:Q8N2X1 xref: UniProtKB:Q8WUH7 xref: UniProtKB:Q96NE9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004660 ! FRMD6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005854 ! frmd6-mlh1 physical interaction relationship: participates_in CCO:I0015012 ! c12orf2-frmd6 physical interaction relationship: participates_in CCO:I0015067 ! frmd6-tsc22d4 physical interaction relationship: transforms_into CCO:B0011898 ! FRMD6_HUMAN-Phosphoserine522 relationship: transforms_into CCO:B0011899 ! FRMD6_HUMAN-Phosphoserine525 relationship: transforms_into CCO:B0066280 ! FRMD6_HUMAN-Phosphoserine544 [Term] id: CCO:B0005268 name: ASF1A_HUMAN def: "Histone chaperone ASF1A" [UniProtKB:Q9Y294] synonym: "Anti-silencing function protein 1 homolog A" EXACT [UniProtKB:Q9Y294] synonym: "CCG1-interacting factor A" EXACT [UniProtKB:Q9Y294] synonym: "CIA" EXACT [UniProtKB:Q9Y294] synonym: "hAsf1" EXACT [UniProtKB:Q9Y294] synonym: "hAsf1a" EXACT [UniProtKB:Q9Y294] synonym: "hCIA" EXACT [UniProtKB:Q9Y294] xref: EMBL:AAD34093.1 xref: EMBL:AAF29110.1 xref: EMBL:AAH10878.1 xref: EMBL:AAK82972.1 xref: EMBL:BAA96542.1 xref: EMBL:BAB15228.1 xref: EMBL:CAB43363.1 xref: EMBL:CAG33628.1 xref: UniProtKB:Q6IA08 xref: UniProtKB:Q9P014 xref: UniProtKB:Q9Y294 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004106 ! ASF1A_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000806 ! chromatin remodeling complex relationship: participates_in CCO:I0005855 ! dkfzp564e2182-tlk1 physical interaction relationship: participates_in CCO:P0000651 ! loss of chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005269 name: Q96AF5_HUMAN def: "ZNF446 protein" [UniProtKB:Q96AF5] xref: EMBL:AAH17206.1 xref: UniProtKB:Q96AF5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006034 ! ZNF446_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005856 ! sufu-znf446 physical interaction relationship: participates_in CCO:I0014962 ! znf435-znf446 physical interaction relationship: participates_in CCO:I0015083 ! znf446-znf496 physical interaction relationship: participates_in CCO:I0015284 ! znf165-znf446 physical interaction relationship: participates_in CCO:I0015347 ! znf263-znf446 physical interaction relationship: participates_in CCO:I0015418 ! znf24-znf446 physical interaction relationship: participates_in CCO:I0015459 ! znf232-znf446 physical interaction relationship: participates_in CCO:I0015735 ! znf193-znf446 physical interaction [Term] id: CCO:B0005270 name: CHM4B_HUMAN def: "Charged multivesicular body protein 4b" [UniProtKB:Q9H444] synonym: "CHMP4b" EXACT [UniProtKB:Q9H444] synonym: "Chromatin-modifying protein 4b" EXACT [UniProtKB:Q9H444] synonym: "hSnf7-2" EXACT [UniProtKB:Q9H444] synonym: "hVps32" EXACT [UniProtKB:Q9H444] synonym: "SNF7 homolog associated with Alix 1" EXACT [UniProtKB:Q9H444] synonym: "SNF7-2" EXACT [UniProtKB:Q9H444] synonym: "Vacuolar protein-sorting-associated protein 7-2" EXACT [UniProtKB:Q9H444] xref: EMBL:AAH33859.1 xref: EMBL:AAQ91194.1 xref: EMBL:BAC79375.1 xref: EMBL:CAC14088.1 xref: UniProtKB:Q53ZD6 xref: UniProtKB:Q9H444 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004350 ! CHMP4B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005857 ! chmp4b-ube2i physical interaction [Term] id: CCO:B0005271 name: MBIP1_HUMAN def: "MAP3K12-binding inhibitory protein 1" [UniProtKB:Q9NS73] synonym: "MAPK upstream kinase-binding inhibitory protein" EXACT [UniProtKB:Q9NS73] synonym: "MUK-binding inhibitory protein" EXACT [UniProtKB:Q9NS73] xref: EMBL:AAF64271.1 xref: EMBL:AAH05197.1 xref: EMBL:AAH16821.1 xref: EMBL:BAA94083.1 xref: EMBL:CAD62615.1 xref: UniProtKB:Q86TZ2 xref: UniProtKB:Q96AS5 xref: UniProtKB:Q9BS93 xref: UniProtKB:Q9NS73 xref: UniProtKB:Q9NZE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005035 ! MBIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005858 ! mbip-mcm7 physical interaction relationship: participates_in CCO:I0015026 ! cep63-mbip physical interaction relationship: participates_in CCO:I0015103 ! mbip-mbip physical interaction relationship: participates_in CCO:I0015248 ! mbip-rap1gds1 physical interaction relationship: participates_in CCO:I0015306 ! mbip-wdr5 physical interaction relationship: participates_in CCO:I0015318 ! dgcr6l-mbip physical interaction relationship: participates_in CCO:I0015447 ! c6orf55-mbip physical interaction relationship: participates_in CCO:I0015495 ! mbip-q96hl7 physical interaction relationship: participates_in CCO:I0015505 ! mbip-ppfia1 physical interaction relationship: participates_in CCO:I0015580 ! mbip-plekhf2 physical interaction relationship: participates_in CCO:I0015591 ! cops4-mbip physical interaction relationship: participates_in CCO:I0015658 ! csrp2bp-mbip physical interaction relationship: participates_in CCO:I0015804 ! lmo3-mbip physical interaction relationship: participates_in CCO:P0000407 ! inactivation of MAPK activity during osmolarity sensing relationship: transforms_into CCO:B0068043 ! MBIP1_HUMAN-Phosphoserine91 [Term] id: CCO:B0005272 name: KC1E_HUMAN def: "Casein kinase I isoform epsilon" [UniProtKB:P49674] synonym: "CKI-epsilon" EXACT [UniProtKB:P49674] synonym: "CKIe" EXACT [UniProtKB:P49674] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P49674] xref: EMBL:AAC41761.1 xref: EMBL:AAH06490.1 xref: EMBL:BAA92345.1 xref: EMBL:BAC10902.1 xref: EMBL:CAA15888.1 xref: EMBL:CAG30315.1 xref: UniProtKB:P49674 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004932 ! CSNK1E_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005861 ! csnk1e-rad54b physical interaction relationship: participates_in CCO:I0006260 ! csnk1e-apc phosphorylation relationship: participates_in CCO:I0015488 ! csnk1e-dvl2 physical interaction relationship: participates_in CCO:I0016214 ! csnk1e-per2 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012511 ! KC1E_HUMAN-Phosphothreonine362 relationship: transforms_into CCO:B0012512 ! KC1E_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0048306 ! KC1E_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0048307 ! KC1E_HUMAN-Phosphoserine389 [Term] id: CCO:B0005273 name: TOLIP_HUMAN def: "Toll-interacting protein" [UniProtKB:Q9H0E2] xref: EMBL:AAH04420.1 xref: EMBL:AAH12057.1 xref: EMBL:AAH18272.1 xref: EMBL:BAB14283.1 xref: EMBL:CAB58118.1 xref: EMBL:CAB66769.1 xref: UniProtKB:Q9H0E2 xref: UniProtKB:Q9H9E6 xref: UniProtKB:Q9UJ69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005808 ! TOLLIP_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001423 ! Toll binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001885 ! interleukin-18 receptor complex relationship: located_in CCO:C0001948 ! interleukin-1 receptor complex relationship: participates_in CCO:I0005863 ! sept1-tollip physical interaction relationship: participates_in CCO:I0014969 ! rbpms-tollip physical interaction relationship: participates_in CCO:I0015060 ! pepp2-tollip physical interaction relationship: participates_in CCO:I0015314 ! dazap2-tollip physical interaction relationship: participates_in CCO:I0015600 ! ldb1-tollip physical interaction relationship: participates_in CCO:I0017335 ! xrn2-tollip physical interaction relationship: participates_in CCO:I0018524 ! tom1-tollip-3 physical interaction relationship: participates_in CCO:I0019064 ! atxn1-tollip physical interaction relationship: participates_in CCO:I0020204 ! tollip-setdb1 physical interaction relationship: participates_in CCO:I0020205 ! tollip-zhx1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0005274 name: RHXF2_HUMAN def: "Rhox homeobox family member 2" [UniProtKB:Q9BQY4] synonym: "Paired-like homeobox protein PEPP-2" EXACT [UniProtKB:Q9BQY4] synonym: "Testis homeobox gene 1" EXACT [UniProtKB:Q9BQY4] xref: EMBL:AAH21719.1 xref: EMBL:AAL02160.1 xref: EMBL:BAB71675.1 xref: EMBL:CAC36519.1 xref: UniProtKB:Q9BQY4 xref: UniProtKB:Q9BR00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005486 ! RHOXF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005864 ! lzts2-pepp2 physical interaction relationship: participates_in CCO:I0005884 ! ccnk-pepp2 physical interaction relationship: participates_in CCO:I0006503 ! rent1-pepp2 physical interaction relationship: participates_in CCO:I0014978 ! cldn7-pepp2 physical interaction relationship: participates_in CCO:I0015000 ! pepp2-rbm11 physical interaction relationship: participates_in CCO:I0015025 ! pepp2-vps25 physical interaction relationship: participates_in CCO:I0015039 ! pepp2-plod3 physical interaction relationship: participates_in CCO:I0015056 ! pepp2-rbpms physical interaction relationship: participates_in CCO:I0015060 ! pepp2-tollip physical interaction relationship: participates_in CCO:I0015131 ! dtx2-pepp2 physical interaction relationship: participates_in CCO:I0015216 ! pepp2-serf2 physical interaction relationship: participates_in CCO:I0015225 ! pepp2-rbm9 physical interaction relationship: participates_in CCO:I0015259 ! kiaa1849-pepp2 physical interaction relationship: participates_in CCO:I0015279 ! c6orf119-pepp2 physical interaction relationship: participates_in CCO:I0015526 ! pepp2-pitx1 physical interaction relationship: participates_in CCO:I0015534 ! dazap2-pepp2 physical interaction relationship: participates_in CCO:I0015681 ! pepp2-sfrs16 physical interaction relationship: participates_in CCO:I0015686 ! mgc4504-pepp2 physical interaction relationship: participates_in CCO:I0015721 ! dvl2-pepp2 physical interaction relationship: participates_in CCO:I0015727 ! efemp2-pepp2 physical interaction relationship: participates_in CCO:I0015754 ! ewsr1-pepp2 physical interaction relationship: participates_in CCO:I0015755 ! hca66-pepp2 physical interaction relationship: participates_in CCO:I0015791 ! pepp2-pepp2 physical interaction relationship: participates_in CCO:I0015806 ! fam46b-pepp2 physical interaction relationship: participates_in CCO:I0017322 ! lsm4-pepp2 physical interaction relationship: participates_in CCO:I0019412 ! plod3-pepp2 physical interaction relationship: participates_in CCO:I0019419 ! efemp2-pepp2-1 physical interaction relationship: participates_in CCO:I0019425 ! mgc4504-pepp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005275 name: KHDR3_HUMAN def: "KH domain-containing, RNA-binding, signal transduction-associated protein 3" [UniProtKB:O75525] synonym: "RNA-binding protein T-Star" EXACT [UniProtKB:O75525] synonym: "Sam68-like mammalian protein 2" EXACT [UniProtKB:O75525] synonym: "Sam68-like phosphotyrosine protein" EXACT [UniProtKB:O75525] synonym: "SLM-2" EXACT [UniProtKB:O75525] xref: EMBL:AAC24857.1 xref: EMBL:AAC99294.1 xref: EMBL:AAC99295.1 xref: EMBL:AAH32606.1 xref: EMBL:AAH68536.1 xref: UniProtKB:O75525 xref: UniProtKB:Q6NUL8 xref: UniProtKB:Q9UPA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004938 ! KHDRBS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005865 ! khdrbs3-rbm7 physical interaction relationship: participates_in CCO:I0005945 ! khdrbs3-siah1 physical interaction relationship: participates_in CCO:I0015029 ! khdrbs3-znf408 physical interaction relationship: participates_in CCO:I0015065 ! bahd1-khdrbs3 physical interaction relationship: participates_in CCO:I0015111 ! khdrbs3-rbmx physical interaction relationship: participates_in CCO:I0015204 ! khdrbs3-lnx physical interaction relationship: participates_in CCO:I0015552 ! hnrpk-khdrbs3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012528 ! KHDR3_HUMAN-Phosphotyrosine5 [Term] id: CCO:B0005276 name: ZN764_HUMAN def: "Zinc finger protein 764" [UniProtKB:Q96H86] xref: EMBL:AAH00016.2 xref: EMBL:AAH08821.1 xref: UniProtKB:Q96H86 xref: UniProtKB:Q9BWS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005967 ! ZNF764_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005866 ! mgc13138-sufu physical interaction relationship: participates_in CCO:I0015205 ! krtap4_12-mgc13138 physical interaction relationship: participates_in CCO:I0015667 ! mdfi-mgc13138 physical interaction relationship: participates_in CCO:I0015705 ! mgc13138-plscr1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005277 name: MED4_HUMAN def: "Mediator of RNA polymerase II transcription subunit 4" [UniProtKB:Q9NPJ6] synonym: "Activator-recruited cofactor 36 kDa component" EXACT [UniProtKB:Q9NPJ6] synonym: "ARC36" EXACT [UniProtKB:Q9NPJ6] synonym: "DRIP36" EXACT [UniProtKB:Q9NPJ6] synonym: "Mediator complex subunit 4" EXACT [UniProtKB:Q9NPJ6] synonym: "TRAP/SMCC/PC2 subunit p36 subunit" EXACT [UniProtKB:Q9NPJ6] synonym: "Vitamin D3 receptor-interacting protein complex 36 kDa component" EXACT [UniProtKB:Q9NPJ6] xref: EMBL:AAF29090.1 xref: EMBL:AAF37289.1 xref: EMBL:AAG22542.1 xref: EMBL:AAH05189.1 xref: EMBL:BAA91987.1 xref: EMBL:BAD96433.1 xref: EMBL:BAD96737.1 xref: EMBL:CAG33557.1 xref: EMBL:CAG46629.1 xref: EMBL:CAI17018.1 xref: EMBL:CAI17020.1 xref: UniProtKB:Q53GB4 xref: UniProtKB:Q53H68 xref: UniProtKB:Q5T912 xref: UniProtKB:Q6FHC4 xref: UniProtKB:Q6IA79 xref: UniProtKB:Q9BS95 xref: UniProtKB:Q9NPJ6 xref: UniProtKB:Q9NYR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005075 ! MED4_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005869 ! mcrs1-med4 physical interaction relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0015148 ! med4-tnfaip8 physical interaction relationship: participates_in CCO:I0015233 ! ap2m1-med4 physical interaction relationship: participates_in CCO:I0016032 ! q9nwa0-vdrip-4 physical interaction relationship: participates_in CCO:I0016033 ! q9nwa0-vdrip-5 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0016235 ! q9nwa0-vdrip-3 physical interaction relationship: participates_in CCO:I0017350 ! q9nwa0-vdrip-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0017850 ! q9nwa0-vdrip-2 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway [Term] id: CCO:B0005278 name: UBCP1_HUMAN def: "Ubiquitin-like domain-containing CTD phosphatase 1" [UniProtKB:Q8WVY7] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q8WVY7] xref: EMBL:AAH13425.2 xref: EMBL:AAS68538.1 xref: EMBL:BAB71628.1 xref: UniProtKB:Q8WVY7 xref: UniProtKB:Q96DK5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005859 ! UBLCP1_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005870 ! psmd2-ublcp1 physical interaction relationship: participates_in CCO:I0015704 ! tsc22d4-ublcp1 physical interaction [Term] id: CCO:B0005279 name: TBC17_HUMAN def: "TBC1 domain family member 17" [UniProtKB:Q9HA65] xref: EMBL:AAH03516.1 xref: EMBL:BAB13991.1 xref: UniProtKB:Q9HA65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005738 ! TBC1D17_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0005871 ! cdkn2d-tbc1d17 physical interaction relationship: participates_in CCO:I0008479 ! gps1-tbc1d17 physical interaction relationship: participates_in CCO:I0015792 ! optn-tbc1d17 physical interaction relationship: participates_in CCO:I0019912 ! ascc2-tbc1d17 physical interaction relationship: participates_in CCO:I0020184 ! tbc1d17-gtf3c1 physical interaction relationship: participates_in CCO:I0020271 ! cct5-tbc1d17 physical interaction relationship: participates_in CCO:I0020308 ! fbl-tbc1d17 physical interaction relationship: participates_in CCO:I0020425 ! rab1a-tbc1d17 physical interaction relationship: participates_in CCO:I0020541 ! dhx29-tbc1d17 physical interaction relationship: participates_in CCO:I0020607 ! nipsnap1-tbc1d17 physical interaction relationship: participates_in CCO:I0020664 ! slc1a5-tbc1d17 physical interaction relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0005280 name: HGS_HUMAN def: "Hepatocyte growth factor-regulated tyrosine kinase substrate" [UniProtKB:O14964] synonym: "Hrs" EXACT [UniProtKB:O14964] synonym: "Protein pp110" EXACT [UniProtKB:O14964] xref: EMBL:AAC51929.1 xref: EMBL:AAF82361.1 xref: EMBL:AAH03565.1 xref: EMBL:AAP88756.1 xref: EMBL:BAA23366.1 xref: UniProtKB:O14964 xref: UniProtKB:Q9NR36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004804 ! HGS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005873 ! hgs-ube2i physical interaction relationship: participates_in CCO:I0005902 ! hgs-krt18 physical interaction relationship: participates_in CCO:I0007649 ! gfi1b-hgs physical interaction relationship: participates_in CCO:I0014961 ! exoc7-hgs physical interaction relationship: participates_in CCO:I0015125 ! hgs-ushbp1 physical interaction relationship: participates_in CCO:I0015155 ! ehmt2-hgs physical interaction relationship: participates_in CCO:I0015227 ! exoc8-hgs physical interaction relationship: participates_in CCO:I0015290 ! hgs-nmi physical interaction relationship: participates_in CCO:I0015392 ! hgs-ldoc1 physical interaction relationship: participates_in CCO:I0015511 ! begain-hgs physical interaction relationship: participates_in CCO:I0015538 ! hgs-loc541468 physical interaction relationship: participates_in CCO:I0015551 ! dazap2-hgs physical interaction relationship: participates_in CCO:I0015651 ! hgs-stam2 physical interaction relationship: participates_in CCO:I0015666 ! crsp9-hgs physical interaction relationship: participates_in CCO:I0015737 ! hgs-ubqln1 physical interaction relationship: participates_in CCO:I0015767 ! hgs-tada2l physical interaction relationship: participates_in CCO:I0015837 ! hgs-stam physical interaction relationship: participates_in CCO:I0015850 ! hgs-tsg101 physical interaction relationship: participates_in CCO:I0018890 ! ubqln4-hgs physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002693 ! negative regulation of JAK-STAT cascade relationship: transforms_into CCO:B0012185 ! HGS_HUMAN-Phosphotyrosine216 relationship: transforms_into CCO:B0012186 ! HGS_HUMAN-Phosphotyrosine308 relationship: transforms_into CCO:B0012187 ! HGS_HUMAN-Phosphotyrosine329 relationship: transforms_into CCO:B0012188 ! HGS_HUMAN-Phosphotyrosine334 relationship: transforms_into CCO:B0066802 ! HGS_HUMAN-Phosphotyrosine132 [Term] id: CCO:B0005281 name: M1IP1_HUMAN def: "Mid1-interacting protein 1" [UniProtKB:Q9NPA3] synonym: "Gastrulation-specific G12-like protein" EXACT [UniProtKB:Q9NPA3] synonym: "Mid1-interacting G12-like protein" EXACT [UniProtKB:Q9NPA3] synonym: "Protein STRAIT11499" EXACT [UniProtKB:Q9NPA3] xref: EMBL:AAH08908.1 xref: EMBL:AAH19332.1 xref: EMBL:BAA91580.1 xref: EMBL:CAB89113.1 xref: EMBL:CAG33501.1 xref: EMBL:DAA01482.1 xref: UniProtKB:Q9NPA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005002 ! MID1IP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: participates_in CCO:I0005877 ! mid1ip1-sufu physical interaction relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: transforms_into CCO:B0012713 ! M1IP1_HUMAN-Phosphoserine75 [Term] id: CCO:B0005282 name: NOC4L_HUMAN def: "Nucleolar complex protein 4 homolog" [UniProtKB:Q9BVI4] synonym: "NOC4 protein homolog" EXACT [UniProtKB:Q9BVI4] synonym: "NOC4-like protein" EXACT [UniProtKB:Q9BVI4] synonym: "Nucleolar complex-associated protein 4-like protein" EXACT [UniProtKB:Q9BVI4] xref: EMBL:AAH01191.1 xref: EMBL:AAH07893.2 xref: EMBL:AAH71958.1 xref: EMBL:BAC11020.1 xref: UniProtKB:Q8N2S5 xref: UniProtKB:Q96I14 xref: UniProtKB:Q9BVI4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005201 ! NOC4L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000322 ! small nucleolar ribonucleoprotein complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0005879 ! mgc3162-sssca1 physical interaction relationship: participates_in CCO:I0015614 ! mgc3162-tsc22d4 physical interaction [Term] id: CCO:B0005283 name: TS101_HUMAN def: "Tumor susceptibility gene 101 protein" [UniProtKB:Q99816] xref: EMBL:AAC52083.1 xref: EMBL:AAH02487.1 xref: UniProtKB:Q99816 xref: UniProtKB:Q9BUM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005838 ! TSG101_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000354 ! multivesicular body relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005880 ! c10orf3-tsg101 physical interaction relationship: participates_in CCO:I0006519 ! daxx-tsg101 physical interaction relationship: participates_in CCO:I0006520 ! dax-tsg101 physical interaction relationship: participates_in CCO:I0006521 ! dax-tsg101-1 physical interaction relationship: participates_in CCO:I0006522 ! tsg101-daxx physical interaction relationship: participates_in CCO:I0007312 ! rps27a-tsg101-1 direct interaction relationship: participates_in CCO:I0015091 ! ppfibp2-tsg101 physical interaction relationship: participates_in CCO:I0015139 ! lrsam1-tsg101 physical interaction relationship: participates_in CCO:I0015266 ! krt15-tsg101 physical interaction relationship: participates_in CCO:I0015848 ! tsg101-vps28-1 physical interaction relationship: participates_in CCO:I0015850 ! hgs-tsg101 physical interaction relationship: participates_in CCO:I0017359 ! dmap1-tsg101 physical interaction relationship: participates_in CCO:I0017853 ! gga1-tsg101-1 physical interaction relationship: participates_in CCO:I0018432 ! hck-tsg101-1 physical interaction relationship: participates_in CCO:I0019488 ! gga3-tsg101-1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0071594 ! TS101_HUMAN-Phosphotyrosine390 [Term] id: CCO:B0005284 name: ING5_HUMAN def: "Inhibitor of growth protein 5" [UniProtKB:Q8WYH8] synonym: "p28ING5" EXACT [UniProtKB:Q8WYH8] xref: EMBL:AAH05370.1 xref: EMBL:AAH71899.1 xref: EMBL:AAL68979.1 xref: EMBL:BAB85078.1 xref: UniProtKB:Q8WYH8 xref: UniProtKB:Q9BS30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004895 ! ING5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005883 ! ing5-mcm6 physical interaction relationship: participates_in CCO:I0015183 ! ing5-mgc2749 physical interaction relationship: participates_in CCO:I0020008 ! gcsh-ing5 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0012418 ! ING5_HUMAN-Phosphoserine118 [Term] id: CCO:B0005285 name: H32_HUMAN def: "Histone H3.2" [UniProtKB:Q71DI3] synonym: "H3/m" EXACT [UniProtKB:Q71DI3] synonym: "H3/o" EXACT [UniProtKB:Q71DI3] xref: EMBL:AAH74969.2 xref: EMBL:AAI30636.1 xref: EMBL:AAI30638.1 xref: EMBL:AAN39283.1 xref: EMBL:AAT68254.1 xref: EMBL:CAI12559.1 xref: EMBL:CAI12561.1 xref: EMBL:CAI12566.1 xref: UniProtKB:A2BDF6 xref: UniProtKB:A6NFS4 xref: UniProtKB:Q6B053 xref: UniProtKB:Q71DI3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004759 ! HIST2H3A_human relationship: encoded_by CCO:G0004760 ! HIST2H3C_human relationship: encoded_by CCO:G0018100 ! HIST2H3D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005886 ! hist2h3c-nasp physical interaction relationship: transforms_into CCO:B0012060 ! H32_HUMAN-Phosphothreonine4 relationship: transforms_into CCO:B0012061 ! H32_HUMAN-N6-acetyllysine5 relationship: transforms_into CCO:B0012062 ! H32_HUMAN-N6-methyllysine5 relationship: transforms_into CCO:B0012063 ! H32_HUMAN-Citrulline9 relationship: transforms_into CCO:B0012064 ! H32_HUMAN-dimethylarginine9 relationship: transforms_into CCO:B0012065 ! H32_HUMAN-N6,N6,N6-trimethyllysine10 relationship: transforms_into CCO:B0012066 ! H32_HUMAN-N6,N6-dimethyllysine10 relationship: transforms_into CCO:B0012067 ! H32_HUMAN-N6-acetyllysine10 relationship: transforms_into CCO:B0012068 ! H32_HUMAN-N6-methyllysine10 relationship: transforms_into CCO:B0012069 ! H32_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0012070 ! H32_HUMAN-Phosphothreonine12 relationship: transforms_into CCO:B0012071 ! H32_HUMAN-N6-acetyllysine15 relationship: transforms_into CCO:B0012072 ! H32_HUMAN-dimethylarginine18 relationship: transforms_into CCO:B0012073 ! H32_HUMAN-Citrulline18 relationship: transforms_into CCO:B0012074 ! H32_HUMAN-N6-acetyllysine19 relationship: transforms_into CCO:B0012075 ! H32_HUMAN-N6-methyllysine19 relationship: transforms_into CCO:B0012076 ! H32_HUMAN-N6-acetyllysine24 relationship: transforms_into CCO:B0012077 ! H32_HUMAN-N6-methyllysine24 relationship: transforms_into CCO:B0012078 ! H32_HUMAN-N6,N6,N6-trimethyllysine28 relationship: transforms_into CCO:B0012079 ! H32_HUMAN-N6,N6-dimethyllysine28 relationship: transforms_into CCO:B0012080 ! H32_HUMAN-N6-acetyllysine28 relationship: transforms_into CCO:B0012081 ! H32_HUMAN-N6-methyllysine28 relationship: transforms_into CCO:B0012082 ! H32_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0012083 ! H32_HUMAN-N6,N6,N6-trimethyllysine37 relationship: transforms_into CCO:B0012084 ! H32_HUMAN-N6,N6-dimethyllysine37 relationship: transforms_into CCO:B0012085 ! H32_HUMAN-N6-acetyllysine37 relationship: transforms_into CCO:B0012086 ! H32_HUMAN-N6-methyllysine37 relationship: transforms_into CCO:B0012087 ! H32_HUMAN-N6,N6,N6-trimethyllysine57 relationship: transforms_into CCO:B0012088 ! H32_HUMAN-N6-acetyllysine57 relationship: transforms_into CCO:B0012089 ! H32_HUMAN-N6-methyllysine57 relationship: transforms_into CCO:B0012090 ! H32_HUMAN-N6-methyllysine65 relationship: transforms_into CCO:B0012091 ! H32_HUMAN-N6,N6,N6-trimethyllysine80 relationship: transforms_into CCO:B0012092 ! H32_HUMAN-N6,N6-dimethyllysine80 relationship: transforms_into CCO:B0012093 ! H32_HUMAN-N6-acetyllysine80 relationship: transforms_into CCO:B0012094 ! H32_HUMAN-N6-methyllysine80 relationship: transforms_into CCO:B0012095 ! H32_HUMAN-N6-methyllysine123 [Term] id: CCO:B0005286 name: CN048_HUMAN def: "Uncharacterized protein C14orf48" [UniProtKB:Q8NCU1] xref: EMBL:AAH21728.1 xref: EMBL:BAC05156.1 xref: UniProtKB:Q8N7S1 xref: UniProtKB:Q8NCU1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004374 ! C14orf48_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005888 ! c14orf48-c18orf24 physical interaction [Term] id: CCO:B0005288 name: ARI2_HUMAN def: "Protein ariadne-2 homolog" [UniProtKB:O95376] synonym: "ARI-2" EXACT [UniProtKB:O95376] synonym: "Triad1 protein" EXACT [UniProtKB:O95376] xref: EMBL:AAC82469.1 xref: EMBL:AAG09696.1 xref: EMBL:AAH00422.1 xref: EMBL:CAA10276.1 xref: UniProtKB:O95376 xref: UniProtKB:Q9HBZ6 xref: UniProtKB:Q9UEM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004092 ! ARIH2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005890 ! arih2-bub1 physical interaction relationship: participates_in CCO:I0007994 ! arih2-ptn physical interaction relationship: participates_in CCO:I0007995 ! arih2-tp53 physical interaction relationship: participates_in CCO:I0008066 ! arih2-centd2 physical interaction relationship: participates_in CCO:I0008190 ! arih2-ppp2r1a physical interaction relationship: participates_in CCO:I0008357 ! arih2-eml4 physical interaction relationship: participates_in CCO:I0019652 ! arih2-htatip physical interaction relationship: participates_in CCO:I0019898 ! arih2-il4r physical interaction relationship: transforms_into CCO:B0010601 ! ARI2_HUMAN-Phosphoserine353 [Term] id: CCO:B0005289 name: Q8NHQ3_HUMAN def: "RBBP8 protein" [UniProtKB:Q8NHQ3] xref: EMBL:AAH30590.1 xref: UniProtKB:Q8NHQ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005442 ! RBBP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005891 ! pin1-rbbp8 physical interaction [Term] id: CCO:B0005290 name: F131C_HUMAN def: "Protein FAM131C" [UniProtKB:Q96AQ9] xref: EMBL:AAH16848.1 xref: EMBL:AAH37394.1 xref: EMBL:BAC04282.1 xref: EMBL:CAI16143.1 xref: UniProtKB:Q5T5Q5 xref: UniProtKB:Q8N3X3 xref: UniProtKB:Q8N9P9 xref: UniProtKB:Q96AQ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004604 ! FAM131C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005894 ! c1orf117-mad1l1 physical interaction relationship: participates_in CCO:I0015023 ! c1orf117-dnaja3 physical interaction relationship: participates_in CCO:I0015273 ! c1orf117-ewsr1 physical interaction relationship: participates_in CCO:I0015363 ! c1orf117-grn physical interaction [Term] id: CCO:B0005291 name: TCPE_HUMAN def: "T-complex protein 1 subunit epsilon" [UniProtKB:P48643] synonym: "CCT-epsilon" EXACT [UniProtKB:P48643] synonym: "TCP-1-epsilon" EXACT [UniProtKB:P48643] xref: EMBL:AAH06543.1 xref: EMBL:AAH35499.1 xref: EMBL:BAA07894.2 xref: UniProtKB:P48643 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005752 ! CCT5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005895 ! cct5-sssca1 physical interaction relationship: participates_in CCO:I0008076 ! cct5-tp53 physical interaction relationship: participates_in CCO:I0016468 ! ikbke-cct5 physical interaction relationship: participates_in CCO:I0016602 ! map3k1-cct5 physical interaction relationship: participates_in CCO:I0016685 ! map3k3-cct5 physical interaction relationship: participates_in CCO:I0016964 ! tbk1-cct5 physical interaction relationship: participates_in CCO:I0019687 ! cct5-ikbkap physical interaction relationship: participates_in CCO:I0020271 ! cct5-tbc1d17 physical interaction relationship: transforms_into CCO:B0041344 ! TCPE_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005292 name: SPOP_HUMAN def: "Speckle-type POZ protein" [UniProtKB:O43791] synonym: "HIB homolog 1" EXACT [UniProtKB:O43791] synonym: "Roadkill homolog 1" EXACT [UniProtKB:O43791] xref: EMBL:AAH01269.1 xref: EMBL:AAH03385.1 xref: EMBL:BAD96309.1 xref: EMBL:CAA04199.1 xref: UniProtKB:O43791 xref: UniProtKB:Q53HJ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005665 ! SPOP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005896 ! ddit3-spop physical interaction relationship: participates_in CCO:I0015588 ! rxrb-spop physical interaction relationship: participates_in CCO:I0015763 ! myd88-spop physical interaction [Term] id: CCO:B0005293 name: KR412_HUMAN def: "Keratin-associated protein 4-12" [UniProtKB:Q9BQ66] synonym: "Keratin-associated protein 4.12" EXACT [UniProtKB:Q9BQ66] synonym: "Ultrahigh sulfur keratin-associated protein 4.12" EXACT [UniProtKB:Q9BQ66] xref: EMBL:AAH04180.1 xref: EMBL:AAH04212.1 xref: EMBL:AAI01160.1 xref: EMBL:AAI01161.1 xref: EMBL:AAI01163.1 xref: EMBL:CAC27582.1 xref: UniProtKB:A3KMC5 xref: UniProtKB:Q495I0 xref: UniProtKB:Q9BQ66 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004960 ! KRTAP4-12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0001886 ! keratin filament relationship: participates_in CCO:I0005900 ! ccnk-krtap4_12 physical interaction relationship: participates_in CCO:I0014971 ! krtap4_12-otx1 physical interaction relationship: participates_in CCO:I0015072 ! krtap4_12-pnkp physical interaction relationship: participates_in CCO:I0015098 ! krtap4_12-znf250 physical interaction relationship: participates_in CCO:I0015174 ! hoxb9-krtap4_12 physical interaction relationship: participates_in CCO:I0015205 ! krtap4_12-mgc13138 physical interaction relationship: participates_in CCO:I0015215 ! cbx2-krtap4_12 physical interaction relationship: participates_in CCO:I0015223 ! cry1-krtap4_12 physical interaction relationship: participates_in CCO:I0015238 ! krtap4_12-top3b physical interaction relationship: participates_in CCO:I0015308 ! krtap4_12-znf426 physical interaction relationship: participates_in CCO:I0015330 ! krtap4_12-pfkl physical interaction relationship: participates_in CCO:I0015352 ! krtap4_12-znf439 physical interaction relationship: participates_in CCO:I0015393 ! krtap4_12-znf417 physical interaction relationship: participates_in CCO:I0015452 ! krtap4_12-thap7 physical interaction relationship: participates_in CCO:I0015458 ! hoxa1-krtap4_12 physical interaction relationship: participates_in CCO:I0015500 ! cdc42ep1-krtap4_12 physical interaction relationship: participates_in CCO:I0015515 ! krtap4_12-meox2 physical interaction relationship: participates_in CCO:I0015567 ! eif4el3-krtap4_12 physical interaction relationship: participates_in CCO:I0015582 ! krtap4_12-znf165 physical interaction relationship: participates_in CCO:I0015633 ! krtap4_12-znf408 physical interaction relationship: participates_in CCO:I0015647 ! krtap4_12-znf655 physical interaction relationship: participates_in CCO:I0015664 ! drr1-krtap4_12 physical interaction relationship: participates_in CCO:I0015665 ! grap2-krtap4_12 physical interaction relationship: participates_in CCO:I0015679 ! krtap4_12-znf581 physical interaction relationship: participates_in CCO:I0015710 ! krtap4_12-pdgfrb physical interaction relationship: participates_in CCO:I0015746 ! krtap4_12-tceb3b physical interaction relationship: participates_in CCO:I0015766 ! krtap4_12-znf440 physical interaction relationship: participates_in CCO:I0015814 ! cntfr-krtap4_12 physical interaction relationship: participates_in CCO:I0017621 ! rere-krtap4_12 physical interaction [Term] id: CCO:B0005294 name: NDK7_HUMAN def: "Nucleoside diphosphate kinase 7" [UniProtKB:Q9Y5B8] synonym: "EC 2.7.4.6" EXACT [UniProtKB:Q9Y5B8] synonym: "NDK 7" EXACT [UniProtKB:Q9Y5B8] synonym: "NDP kinase 7" EXACT [UniProtKB:Q9Y5B8] synonym: "nm23-H7" EXACT [UniProtKB:Q9Y5B8] xref: EMBL:AAD34622.1 xref: EMBL:AAH06983.1 xref: EMBL:CAI18887.1 xref: EMBL:CAI19238.1 xref: EMBL:CAI22851.1 xref: UniProtKB:Q5TGZ4 xref: UniProtKB:Q9Y5B8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005166 ! NME7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000936 ! nucleoside diphosphate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005903 ! krt18-nme7 physical interaction relationship: participates_in CCO:I0015688 ! nme7-znf263 physical interaction [Term] id: CCO:B0005295 name: PCTK3_HUMAN def: "Serine/threonine-protein kinase PCTAIRE-3" [UniProtKB:Q07002] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q07002] synonym: "PCTAIRE-motif protein kinase 3" EXACT [UniProtKB:Q07002] xref: EMBL:AAH11526.1 xref: EMBL:AAP35963.1 xref: EMBL:AAR13065.1 xref: EMBL:AAR13066.1 xref: EMBL:CAA47005.1 xref: EMBL:CAH72012.1 xref: EMBL:EAW91559.1 xref: EMBL:EAW91560.1 xref: UniProtKB:Q07002 xref: UniProtKB:Q5VXQ2 xref: UniProtKB:Q6V3A2 xref: UniProtKB:Q6V3A3 xref: UniProtKB:Q96F90 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005283 ! PCTK3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005904 ! ccnk-pctk3 physical interaction relationship: transforms_into CCO:B0013446 ! PCTK3_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0013447 ! PCTK3_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0013448 ! PCTK3_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0013449 ! PCTK3_HUMAN-Phosphoserine132 [Term] id: CCO:B0005296 name: HM20A_HUMAN def: "High mobility group protein 20A" [UniProtKB:Q9NP66] synonym: "HMG box-containing protein 20A" EXACT [UniProtKB:Q9NP66] synonym: "HMG domain-containing protein HMGX1" EXACT [UniProtKB:Q9NP66] xref: EMBL:AAF66706.1 xref: EMBL:AAH21959.1 xref: EMBL:AAP35362.1 xref: EMBL:BAA91782.1 xref: EMBL:BAD96820.1 xref: EMBL:CAB90815.1 xref: EMBL:CAB90816.1 xref: EMBL:EAW99201.1 xref: UniProtKB:A6NHY3 xref: UniProtKB:Q53G31 xref: UniProtKB:Q9NP66 xref: UniProtKB:Q9NSF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004810 ! HMG20A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005906 ! hmg20a-rbm7 physical interaction relationship: participates_in CCO:I0005910 ! ccnk-hmg20a physical interaction relationship: participates_in CCO:I0014973 ! hmg20a-tesc physical interaction relationship: participates_in CCO:I0015281 ! hmg20a-magoh2 physical interaction relationship: participates_in CCO:I0015682 ! hmg20a-hpcal1 physical interaction relationship: participates_in CCO:I0015716 ! hmg20a-hmg20a physical interaction relationship: participates_in CCO:I0015750 ! dtnb-hmg20a physical interaction relationship: participates_in CCO:I0019433 ! tesc-hmg20a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066820 ! HM20A_HUMAN-Phosphoserine105 [Term] id: CCO:B0005297 name: ZN263_HUMAN def: "Zinc finger protein 263" [UniProtKB:O14978] synonym: "Zinc finger protein FPM315" EXACT [UniProtKB:O14978] synonym: "Zinc finger protein with KRAB and SCAN domains 12" EXACT [UniProtKB:O14978] xref: EMBL:AAC24490.1 xref: EMBL:AAH08805.1 xref: EMBL:BAA21853.1 xref: UniProtKB:O14978 xref: UniProtKB:O43387 xref: UniProtKB:Q96H95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005958 ! ZNF263_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005907 ! sufu-znf263 physical interaction relationship: participates_in CCO:I0015126 ! efemp2-znf263 physical interaction relationship: participates_in CCO:I0015347 ! znf263-znf446 physical interaction relationship: participates_in CCO:I0015461 ! spg21-znf263 physical interaction relationship: participates_in CCO:I0015468 ! trim41-znf263 physical interaction relationship: participates_in CCO:I0015547 ! scand1-znf263 physical interaction relationship: participates_in CCO:I0015594 ! dvl2-znf263 physical interaction relationship: participates_in CCO:I0015688 ! nme7-znf263 physical interaction relationship: participates_in CCO:I0015706 ! plekhf2-znf263 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005298 name: KAP0_HUMAN def: "cAMP-dependent protein kinase type I-alpha regulatory subunit" [UniProtKB:P10644] synonym: "Tissue-specific extinguisher 1" EXACT [UniProtKB:P10644] synonym: "TSE1" EXACT [UniProtKB:P10644] xref: EMBL:AAB50921.1 xref: EMBL:AAB50922.1 xref: EMBL:AAH36285.1 xref: EMBL:AAH93042.1 xref: EMBL:CAA68925.1 xref: UniProtKB:P10644 xref: UniProtKB:Q567S7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004930 ! PRKAR1A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0004464 ! cAMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0005908 ! prkar1a-pycard physical interaction relationship: participates_in CCO:I0015112 ! mgc13057-prkar1a physical interaction relationship: participates_in CCO:I0015598 ! plekhf2-prkar1a physical interaction relationship: participates_in CCO:I0015823 ! akap10-prkar1a physical interaction relationship: participates_in CCO:I0015903 ! prkaca-prkar1a-1 physical interaction relationship: participates_in CCO:I0015904 ! rfc2-prkar1a-1 physical interaction relationship: participates_in CCO:I0015905 ! rfc2-prkar1a-2 physical interaction relationship: participates_in CCO:I0015906 ! prkar1a-rfc2-1 physical interaction relationship: participates_in CCO:I0018602 ! rfc2-prkar1a-4 physical interaction relationship: participates_in CCO:I0018603 ! rfc2-prkar1a-5 physical interaction relationship: participates_in CCO:I0018604 ! rfc2-prkar1a-6 physical interaction relationship: participates_in CCO:I0019241 ! rfc2-prkar1a-3 physical interaction relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0012507 ! KAP0_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0012508 ! KAP0_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0012509 ! KAP0_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0012510 ! KAP0_HUMAN-Phosphoserine101 [Term] id: CCO:B0005299 name: AMOL2_HUMAN def: "Angiomotin-like protein 2" [UniProtKB:Q9Y2J4] synonym: "LCCP" EXACT [UniProtKB:Q9Y2J4] synonym: "Leman coiled-coil protein" EXACT [UniProtKB:Q9Y2J4] xref: EMBL:AAD56361.2 xref: EMBL:AAH11454.1 xref: EMBL:BAA76833.1 xref: EMBL:BAD97318.1 xref: UniProtKB:Q53EP1 xref: UniProtKB:Q96F99 xref: UniProtKB:Q9UKB4 xref: UniProtKB:Q9Y2J4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004050 ! AMOTL2_human relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000475 ! tight junction relationship: participates_in CCO:I0005911 ! amotl2-kntc2 physical interaction relationship: participates_in CCO:I0005912 ! amotl2-mad1l1 physical interaction relationship: participates_in CCO:I0015278 ! amotl2-mpp1 physical interaction relationship: participates_in CCO:I0015520 ! amotl2-gng11 physical interaction [Term] id: CCO:B0005300 name: TAK1L_HUMAN def: "TAK1-like protein" [UniProtKB:P57077] xref: EMBL:AAF81751.1 xref: EMBL:AAF81752.1 xref: EMBL:AAF81753.1 xref: EMBL:AAF81754.1 xref: EMBL:AAH08567.1 xref: EMBL:AAK68718.1 xref: EMBL:AAO16519.1 xref: EMBL:CAB90434.1 xref: UniProtKB:P57077 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005728 ! TAK1L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005914 ! gps2-tak1l physical interaction relationship: participates_in CCO:I0007891 ! tak1l-gps2 physical interaction [Term] id: CCO:B0005301 name: MAF1_HUMAN def: "Repressor of RNA polymerase III transcription MAF1 homolog" [UniProtKB:Q9H063] xref: EMBL:AAH14082.1 xref: EMBL:AAH18714.1 xref: EMBL:AAH31273.1 xref: EMBL:CAB66871.1 xref: EMBL:CAG38494.1 xref: UniProtKB:Q9H063 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005015 ! MAF1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005916 ! ccnd3-maf1 physical interaction relationship: participates_in CCO:I0020330 ! hbxip-maf1 physical interaction relationship: participates_in CCO:I0020454 ! sumo2-maf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001128 ! negative regulation of transcription from RNA polymerase III promoter relationship: transforms_into CCO:B0012759 ! MAF1_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0067847 ! MAF1_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0067848 ! MAF1_HUMAN-Phosphoserine68 [Term] id: CCO:B0005302 name: CTDS1_HUMAN def: "Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1" [UniProtKB:Q9GZU7] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9GZU7] synonym: "NLI-IF" EXACT [UniProtKB:Q9GZU7] synonym: "NLI-interacting factor 3" EXACT [UniProtKB:Q9GZU7] synonym: "Nuclear LIM interactor-interacting factor 3" EXACT [UniProtKB:Q9GZU7] xref: EMBL:AAG15402.1 xref: EMBL:AAG15404.1 xref: EMBL:AAH12977.1 xref: UniProtKB:Q9GZU7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004415 ! CTDSP1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005917 ! cdca3-ctdsp1 physical interaction [Term] id: CCO:B0005303 name: Q8IVB0_HUMAN def: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 3" [UniProtKB:Q8IVB0] xref: EMBL:AAH36089.1 xref: UniProtKB:Q8IVB0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004035 ! MLLT3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005918 ! mcm6-mllt3 physical interaction [Term] id: CCO:B0005304 name: Q8WU02_HUMAN def: "C9orf61 protein" [UniProtKB:Q8WU02] xref: EMBL:AAH21685.1 xref: UniProtKB:Q8WU02 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005919 ! q8wu02-sfn physical interaction relationship: participates_in CCO:I0015317 ! bag3-q8wu02 physical interaction [Term] id: CCO:B0005305 name: LNX1_HUMAN def: "E3 ubiquitin-protein ligase LNX" [UniProtKB:Q8TBB1] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8TBB1] synonym: "Ligand of Numb-protein X 1" EXACT [UniProtKB:Q8TBB1] synonym: "Numb-binding protein 1" EXACT [UniProtKB:Q8TBB1] xref: EMBL:AAH22983.1 xref: EMBL:AAH34737.1 xref: EMBL:AAK15039.1 xref: EMBL:AAQ88692.1 xref: EMBL:AAY41000.1 xref: EMBL:BAB71291.1 xref: UniProtKB:Q4W5K7 xref: UniProtKB:Q8N4C2 xref: UniProtKB:Q8TBB1 xref: UniProtKB:Q96MJ7 xref: UniProtKB:Q9BY20 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004985 ! LNX1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005923 ! lnx-rad54b physical interaction relationship: participates_in CCO:I0014977 ! ldoc1-lnx physical interaction relationship: participates_in CCO:I0015171 ! lnx-traf2 physical interaction relationship: participates_in CCO:I0015204 ! khdrbs3-lnx physical interaction relationship: participates_in CCO:I0015383 ! lnx-pcbd1 physical interaction relationship: participates_in CCO:I0015449 ! kctd13-lnx physical interaction relationship: participates_in CCO:I0015473 ! lnx-trim23 physical interaction relationship: participates_in CCO:I0015523 ! lnx-tsc22d4 physical interaction relationship: participates_in CCO:I0015539 ! lnx-znf297b physical interaction [Term] id: CCO:B0005306 name: MYOZ1_HUMAN def: "Myozenin-1" [UniProtKB:Q9NP98] synonym: "Calsarcin-2" EXACT [UniProtKB:Q9NP98] synonym: "Filamin-, actinin- and telethonin-binding protein" EXACT [UniProtKB:Q9NP98] synonym: "Protein FATZ" EXACT [UniProtKB:Q9NP98] xref: EMBL:AAG24509.1 xref: EMBL:AAG27296.1 xref: EMBL:AAG38940.1 xref: EMBL:AAH25753.1 xref: EMBL:CAB92967.1 xref: EMBL:CAB94568.1 xref: UniProtKB:Q9H1I7 xref: UniProtKB:Q9NP98 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005148 ! MYOZ1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008082 ! FATZ binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0005925 ! actn4-myoz physical interaction relationship: participates_in CCO:I0015119 ! myoz-pnkp physical interaction relationship: participates_in CCO:I0015831 ! actn1-myoz physical interaction [Term] id: CCO:B0005308 name: ZN451_HUMAN def: "Zinc finger protein 451" [UniProtKB:Q9Y4E5] synonym: "Coactivator for steroid receptors" EXACT [UniProtKB:Q9Y4E5] xref: EMBL:AAH21712.2 xref: EMBL:AAH42450.1 xref: EMBL:AAH58853.1 xref: EMBL:AAL17975.1 xref: EMBL:BAA25502.1 xref: EMBL:BAB21793.1 xref: EMBL:CAH71220.1 xref: EMBL:CAI20516.1 xref: UniProtKB:Q5VVF1 xref: UniProtKB:Q86YE4 xref: UniProtKB:Q8N380 xref: UniProtKB:Q8TD15 xref: UniProtKB:Q9C0G1 xref: UniProtKB:Q9NQM1 xref: UniProtKB:Q9Y4E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005961 ! ZNF451_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005928 ! ube2i-znf451 physical interaction relationship: participates_in CCO:I0015326 ! ndp52-znf451 physical interaction relationship: participates_in CCO:I0015467 ! rap1gds1-znf451 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005309 name: RNF37_HUMAN def: "RING finger protein 37" [UniProtKB:O94941] synonym: "U-box domain-containing protein 5" EXACT [UniProtKB:O94941] synonym: "Ubiquitin-conjugating enzyme 7-interacting protein 5" EXACT [UniProtKB:O94941] xref: EMBL:AAH00515.1 xref: EMBL:BAA74883.2 xref: EMBL:CAC09909.1 xref: UniProtKB:O94941 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005521 ! UBOX5_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005931 ! mlh1-ubox5 physical interaction [Term] id: CCO:B0005310 name: UBP5_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 5" [UniProtKB:P45974] synonym: "Deubiquitinating enzyme 5" EXACT [UniProtKB:P45974] synonym: "EC 3.1.2.15" EXACT [UniProtKB:P45974] synonym: "Isopeptidase T" EXACT [UniProtKB:P45974] synonym: "Ubiquitin thioesterase 5" EXACT [UniProtKB:P45974] synonym: "Ubiquitin-specific-processing protease 5" EXACT [UniProtKB:P45974] xref: EMBL:AAA78934.1 xref: EMBL:AAB51314.1 xref: EMBL:AAB51315.1 xref: EMBL:AAC50465.1 xref: EMBL:AAH04889.1 xref: EMBL:AAH05139.1 xref: EMBL:CAA62690.1 xref: UniProtKB:P45974 xref: UniProtKB:Q96J22 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005870 ! USP5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005933 ! tada3l-usp5 physical interaction relationship: participates_in CCO:I0007892 ! tada3l-usp5-1 physical interaction relationship: participates_in CCO:I0014997 ! dvl2-usp5 physical interaction relationship: transforms_into CCO:B0014568 ! UBP5_HUMAN-Phosphothreonine623 relationship: transforms_into CCO:B0014569 ! UBP5_HUMAN-Phosphoserine783 [Term] id: CCO:B0005311 name: GRIN2_HUMAN def: "G protein-regulated inducer of neurite outgrowth 2" [UniProtKB:O60269] synonym: "GRIN2" EXACT [UniProtKB:O60269] xref: EMBL:AAH11672.1 xref: EMBL:BAA25440.2 xref: EMBL:CAI14956.1 xref: UniProtKB:O60269 xref: UniProtKB:Q5SVF0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004727 ! GPRIN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005934 ! kiaa0514-sfn physical interaction relationship: participates_in CCO:I0015122 ! kiaa0514-mdfi physical interaction relationship: participates_in CCO:I0015224 ! kiaa0514-ywhae physical interaction [Term] id: CCO:B0005312 name: PEX26_HUMAN def: "Peroxisome assembly protein 26" [UniProtKB:Q7Z412] synonym: "Peroxin-26" EXACT [UniProtKB:Q7Z412] xref: EMBL:AAH16280.1 xref: EMBL:AAH47320.1 xref: EMBL:BAA90920.1 xref: EMBL:BAA91329.1 xref: EMBL:BAC66616.1 xref: EMBL:BAC78804.1 xref: EMBL:BAC78805.1 xref: EMBL:BAC78806.1 xref: EMBL:BAC78807.1 xref: EMBL:BAC78808.1 xref: EMBL:CAG30248.1 xref: UniProtKB:Q7Z412 xref: UniProtKB:Q7Z413 xref: UniProtKB:Q7Z414 xref: UniProtKB:Q7Z415 xref: UniProtKB:Q7Z416 xref: UniProtKB:Q96B12 xref: UniProtKB:Q9NWQ0 xref: UniProtKB:Q9NXU0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005300 ! PEX26_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000361 ! integral to peroxisomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0005936 ! pex26-sufu physical interaction relationship: participates_in CCO:I0007890 ! pex26-sufu-1 physical interaction relationship: participates_in CCO:I0019304 ! pex26-pex6 physical interaction [Term] id: CCO:B0005313 name: WBP11_HUMAN def: "WW domain-binding protein 11" [UniProtKB:Q9Y2W2] synonym: "Npw38-binding protein" EXACT [UniProtKB:Q9Y2W2] synonym: "NpwBP" EXACT [UniProtKB:Q9Y2W2] synonym: "SH3 domain-binding protein SNP70" EXACT [UniProtKB:Q9Y2W2] synonym: "WBP-11" EXACT [UniProtKB:Q9Y2W2] xref: EMBL:AAD30425.1 xref: EMBL:AAH01621.1 xref: EMBL:AAH16441.2 xref: EMBL:AAH23532.1 xref: EMBL:BAA88410.1 xref: UniProtKB:Q96AY8 xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005912 ! WBP11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014957 ! trip10-wbp11 physical interaction relationship: participates_in CCO:I0015693 ! nck2-wbp11 physical interaction relationship: participates_in CCO:I0015729 ! runx1t1-wbp11 physical interaction relationship: participates_in CCO:I0017620 ! pqbp1-wbp11 physical interaction relationship: participates_in CCO:I0019895 ! arf1-wbp11 physical interaction relationship: transforms_into CCO:B0014655 ! WBP11_HUMAN-Phosphoserine237 relationship: transforms_into CCO:B0014656 ! WBP11_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0014657 ! WBP11_HUMAN-Phosphothreonine252 relationship: transforms_into CCO:B0014658 ! WBP11_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0014659 ! WBP11_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0014660 ! WBP11_HUMAN-Phosphothreonine271 relationship: transforms_into CCO:B0014661 ! WBP11_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0014662 ! WBP11_HUMAN-Phosphothreonine276 relationship: transforms_into CCO:B0014663 ! WBP11_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0014664 ! WBP11_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0014665 ! WBP11_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0014666 ! WBP11_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0014667 ! WBP11_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0071830 ! WBP11_HUMAN-Phosphothreonine328 [Term] id: CCO:B0005314 name: PRS4_HUMAN def: "26S protease regulatory subunit 4" [UniProtKB:P62191] synonym: "P26s4" EXACT [UniProtKB:P62191] synonym: "Proteasome 26S subunit ATPase 1" EXACT [UniProtKB:P62191] xref: EMBL:AAA35484.1 xref: EMBL:AAH00512.1 xref: EMBL:AAH16368.1 xref: EMBL:AAH73818.1 xref: EMBL:CAG33325.1 xref: UniProtKB:P49014 xref: UniProtKB:P62191 xref: UniProtKB:Q03527 xref: UniProtKB:Q6IAW0 xref: UniProtKB:Q96AZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005384 ! PSMC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005939 ! psmc1-psmd2 physical interaction relationship: participates_in CCO:I0008714 ! traf6-psmc1 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0013617 ! PRS4_HUMAN-Phosphotyrosine439 [Term] id: CCO:B0005315 name: KPCZ_HUMAN def: "Protein kinase C zeta type" [UniProtKB:Q05513] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q05513] synonym: "nPKC-zeta" EXACT [UniProtKB:Q05513] xref: EMBL:AAA36488.1 xref: EMBL:AAH08058.1 xref: EMBL:AAH14270.1 xref: EMBL:AAP35745.1 xref: EMBL:CAA78813.1 xref: EMBL:CAI12484.1 xref: EMBL:CAI15438.1 xref: EMBL:CAI21535.1 xref: UniProtKB:Q05513 xref: UniProtKB:Q15207 xref: UniProtKB:Q5SYT5 xref: UniProtKB:Q969S4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004959 ! PRKCZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005940 ! pard6a-prkcz physical interaction relationship: participates_in CCO:I0005989 ! pard6a-prkcz-1 physical interaction relationship: participates_in CCO:I0005991 ! pard6b-prkcz-1 physical interaction relationship: participates_in CCO:I0006831 ! prkcz-pard6b-1 physical interaction relationship: participates_in CCO:I0007062 ! pard6b-prkci-2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0012634 ! KPCZ_HUMAN-Phosphoserine223 relationship: transforms_into CCO:B0012635 ! KPCZ_HUMAN-Phosphothreonine410 relationship: transforms_into CCO:B0012636 ! KPCZ_HUMAN-Phosphothreonine560 [Term] id: CCO:B0005316 name: NDK3_HUMAN def: "Nucleoside diphosphate kinase 3" [UniProtKB:Q13232] synonym: "DR-nm23" EXACT [UniProtKB:Q13232] synonym: "EC 2.7.4.6" EXACT [UniProtKB:Q13232] synonym: "NDK 3" EXACT [UniProtKB:Q13232] synonym: "NDP kinase 3" EXACT [UniProtKB:Q13232] synonym: "NDPKC" EXACT [UniProtKB:Q13232] synonym: "nm23-H3" EXACT [UniProtKB:Q13232] synonym: "Nucleoside diphosphate kinase C" EXACT [UniProtKB:Q13232] xref: EMBL:AAA85097.1 xref: EMBL:AAH00250.1 xref: EMBL:AAK61291.1 xref: UniProtKB:Q13232 xref: UniProtKB:Q9BWH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005165 ! NME3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000936 ! nucleoside diphosphate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005941 ! nme1-nme3 physical interaction relationship: participates_in CCO:I0008137 ! nme3-nme2 physical interaction relationship: participates_in CCO:I0015408 ! nme3-sgta physical interaction relationship: participates_in CCO:I0017535 ! nme3-ubqln4 physical interaction relationship: participates_in CCO:I0018893 ! ubqln4-nme3 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0005317 name: CBX5_HUMAN def: "Chromobox protein homolog 5" [UniProtKB:P45973] synonym: "Antigen p25" EXACT [UniProtKB:P45973] synonym: "Heterochromatin protein 1 homolog alpha" EXACT [UniProtKB:P45973] synonym: "HP1 alpha" EXACT [UniProtKB:P45973] xref: EMBL:AAA72327.1 xref: EMBL:AAB26994.1 xref: EMBL:AAC50553.1 xref: EMBL:AAH06821.1 xref: UniProtKB:P45973 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004232 ! CBX5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005942 ! cbx5-suv39h1 physical interaction relationship: participates_in CCO:I0006674 ! incenp-cbx5-1 physical interaction relationship: participates_in CCO:I0006930 ! smc2-hp1 colocalization relationship: participates_in CCO:I0007394 ! incenp-cbx5-2 physical interaction relationship: participates_in CCO:I0007395 ! cbx5-incenp-1 physical interaction relationship: participates_in CCO:I0007974 ! suv93h1-cbx-1 physical interaction relationship: participates_in CCO:I0015389 ! cbx5-mgc3121 physical interaction relationship: participates_in CCO:I0015756 ! cbx5-tceb3b physical interaction relationship: participates_in CCO:I0017899 ! cbx5-trim28-2 physical interaction relationship: participates_in CCO:I0017900 ! cbx5-trim28-3 physical interaction relationship: participates_in CCO:I0017943 ! suv93h1-cbx5-3 colocalization relationship: participates_in CCO:I0018243 ! cbx5-mbd1-1 physical interaction relationship: participates_in CCO:I0018390 ! mbd1-cbx5-2 physical interaction relationship: participates_in CCO:I0018698 ! mbd1-cbx5-1 physical interaction relationship: participates_in CCO:I0018854 ! cbx5-trim28-1 physical interaction relationship: participates_in CCO:I0019521 ! mbde-cbx5-1 physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0010967 ! CBX5_HUMAN-Phosphothreonine8 relationship: transforms_into CCO:B0010968 ! CBX5_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0010969 ! CBX5_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0010971 ! CBX5_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0010972 ! CBX5_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0010973 ! CBX5_HUMAN-Phosphoserine110 [Term] id: CCO:B0005318 name: Q9BVJ0_HUMAN def: "Transcriptional adaptor 2 (ADA2 homolog, yeast)-like" [UniProtKB:Q9BVJ0] xref: EMBL:AAH01172.1 xref: UniProtKB:Q9BVJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004028 ! TADA2L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005943 ! tada2l-tada3l physical interaction relationship: participates_in CCO:I0015034 ! exoc8-tada2l physical interaction relationship: participates_in CCO:I0015172 ! drr1-tada2l physical interaction relationship: participates_in CCO:I0015767 ! hgs-tada2l physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005319 name: PDLI1_HUMAN def: "PDZ and LIM domain protein 1" [UniProtKB:O00151] synonym: "C-terminal LIM domain protein 1" EXACT [UniProtKB:O00151] synonym: "Elfin" EXACT [UniProtKB:O00151] synonym: "LIM domain protein CLP-36" EXACT [UniProtKB:O00151] xref: EMBL:AAC05580.1 xref: EMBL:AAH00915.1 xref: EMBL:AAH18755.1 xref: EMBL:AAW82438.1 xref: EMBL:CAC32846.1 xref: EMBL:CAH70720.1 xref: EMBL:CAH72341.1 xref: UniProtKB:O00151 xref: UniProtKB:Q5VZH5 xref: UniProtKB:Q9BPZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005291 ! PDLIM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005948 ! actn4-pdlim1 physical interaction relationship: participates_in CCO:I0015113 ! gfap-pdlim1 physical interaction relationship: participates_in CCO:I0015494 ! pdlim1-vim physical interaction relationship: participates_in CCO:I0020557 ! flj10842-pdlim1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013455 ! PDLI1_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0013456 ! PDLI1_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0013457 ! PDLI1_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0013458 ! PDLI1_HUMAN-Phosphotyrosine144 relationship: transforms_into CCO:B0013459 ! PDLI1_HUMAN-Phosphotyrosine151 relationship: transforms_into CCO:B0013460 ! PDLI1_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0013461 ! PDLI1_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0013462 ! PDLI1_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0013463 ! PDLI1_HUMAN-Phosphotyrosine321 [Term] id: CCO:B0005320 name: BATF_HUMAN def: "Basic leucine zipper transcriptional factor ATF-like" [UniProtKB:Q16520] synonym: "B-ATF" EXACT [UniProtKB:Q16520] synonym: "SF-HT-activated gene 2 protein" EXACT [UniProtKB:Q16520] synonym: "SFA-2" EXACT [UniProtKB:Q16520] xref: EMBL:AAC50314.1 xref: EMBL:AAC78243.1 xref: EMBL:AAD51372.1 xref: EMBL:AAH32294.1 xref: EMBL:BAA07686.1 xref: UniProtKB:Q16520 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004142 ! BATF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005951 ! batf-ddit3 physical interaction relationship: participates_in CCO:I0015503 ! batf-snapc5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005321 name: PIAS2_HUMAN def: "E3 SUMO-protein ligase PIAS2" [UniProtKB:O75928] synonym: "Androgen receptor-interacting protein 3" EXACT [UniProtKB:O75928] synonym: "ARIP3" EXACT [UniProtKB:O75928] synonym: "DAB2-interacting protein" EXACT [UniProtKB:O75928] synonym: "DIP" EXACT [UniProtKB:O75928] synonym: "Miz1" EXACT [UniProtKB:O75928] synonym: "Msx-interacting zinc finger protein" EXACT [UniProtKB:O75928] synonym: "PIAS-NY protein" EXACT [UniProtKB:O75928] synonym: "Protein inhibitor of activated STAT x" EXACT [UniProtKB:O75928] synonym: "Protein inhibitor of activated STAT2" EXACT [UniProtKB:O75928] xref: EMBL:AAC36704.1 xref: EMBL:AAC36705.1 xref: EMBL:AAH15190.1 xref: EMBL:AAK48938.1 xref: UniProtKB:O75927 xref: UniProtKB:O75928 xref: UniProtKB:Q96BT5 xref: UniProtKB:Q96KE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005311 ! PIAS2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0005952 ! pias2-ube2i physical interaction relationship: participates_in CCO:I0018472 ! bat1-piasx physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0005322 name: SMAD4_HUMAN def: "Mothers against decapentaplegic homolog 4" [UniProtKB:Q13485] synonym: "Deletion target in pancreatic carcinoma 4" EXACT [UniProtKB:Q13485] synonym: "hSMAD4" EXACT [UniProtKB:Q13485] synonym: "Mothers against DPP homolog 4" EXACT [UniProtKB:Q13485] synonym: "SMAD 4" EXACT [UniProtKB:Q13485] xref: EMBL:AAA91041.1 xref: EMBL:AAC03051.1 xref: EMBL:AAH02379.1 xref: UniProtKB:Q13485 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005624 ! SMAD4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005954 ! smad4-ube2i physical interaction relationship: participates_in CCO:I0008982 ! smad3-smad4-1 direct interaction relationship: participates_in CCO:I0015442 ! smad4-smad9 physical interaction relationship: participates_in CCO:I0015680 ! ewsr1-smad4 physical interaction relationship: participates_in CCO:I0017977 ! ski-madh4-1 physical interaction relationship: participates_in CCO:I0018135 ! dach-madh4-1 physical interaction relationship: participates_in CCO:I0018582 ! dach-madh4-2 physical interaction relationship: participates_in CCO:I0018583 ! madh4-ski-1 physical interaction relationship: participates_in CCO:I0018584 ! dach-madh4-3 physical interaction relationship: participates_in CCO:I0018750 ! ski-smad4-1 direct interaction relationship: participates_in CCO:I0019185 ! cebpb-smad4 physical interaction relationship: participates_in CCO:I0019325 ! smad2-smad4-2 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000723 ! SMAD protein complex assembly relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005323 name: FANCA_HUMAN def: "Fanconi anemia group A protein" [UniProtKB:O15360] synonym: "Protein FACA" EXACT [UniProtKB:O15360] xref: EMBL:AAC28331.1 xref: EMBL:AAC28751.1 xref: EMBL:AAC33304.1 xref: EMBL:AAC33401.1 xref: EMBL:AAH08979.1 xref: EMBL:AAS99350.1 xref: EMBL:CAA12393.1 xref: EMBL:CAA12394.1 xref: EMBL:CAA67610.1 xref: EMBL:CAB05445.1 xref: UniProtKB:O15360 xref: UniProtKB:O75266 xref: UniProtKB:Q6PL10 xref: UniProtKB:Q92497 xref: UniProtKB:Q96H18 xref: UniProtKB:Q9UEA5 xref: UniProtKB:Q9UEL8 xref: UniProtKB:Q9UEL9 xref: UniProtKB:Q9UPK3 xref: UniProtKB:Q9Y6M2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004608 ! FANCA_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005959 ! fanca-fancg physical interaction relationship: participates_in CCO:I0007587 ! fancg-fancf-1 physical interaction relationship: transforms_into CCO:B0011840 ! FANCA_HUMAN-Phosphoserine849 relationship: transforms_into CCO:B0011841 ! FANCA_HUMAN-Phosphoserine850 relationship: transforms_into CCO:B0011842 ! FANCA_HUMAN-Phosphoserine858 relationship: transforms_into CCO:B0011843 ! FANCA_HUMAN-Phosphoserine1449 [Term] id: CCO:B0005324 name: CEBPG_HUMAN def: "CCAAT/enhancer-binding protein gamma" [UniProtKB:P53567] synonym: "C/EBP gamma" EXACT [UniProtKB:P53567] xref: EMBL:AAC50201.1 xref: EMBL:AAH07582.1 xref: EMBL:AAH13128.1 xref: EMBL:AAV38622.1 xref: EMBL:AAV38623.1 xref: UniProtKB:P53567 xref: UniProtKB:Q5U052 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004318 ! CEBPG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005961 ! cebpg-ddit3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002050 ! natural killer cell mediated cytotoxicity relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002527 ! positive regulation of DNA repair relationship: participates_in CCO:P0003022 ! positive regulation of transcription factor activity [Term] id: CCO:B0005325 name: IL1R1_HUMAN def: "Interleukin-1 receptor type I precursor" [UniProtKB:P14778] synonym: "CD121 antigen-like family member A" EXACT [UniProtKB:P14778] synonym: "CD121a antigen" EXACT [UniProtKB:P14778] synonym: "IL-1R-1" EXACT [UniProtKB:P14778] synonym: "IL-1R-alpha" EXACT [UniProtKB:P14778] synonym: "IL-1RT1" EXACT [UniProtKB:P14778] synonym: "p80" EXACT [UniProtKB:P14778] xref: EMBL:AAA59137.1 xref: EMBL:AAH67506.1 xref: EMBL:AAH75062.1 xref: EMBL:AAH75063.1 xref: EMBL:AAM88423.1 xref: EMBL:CAA34773.1 xref: UniProtKB:P14778 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004881 ! IL1R1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_function CCO:F0001256 ! interleukin-1, Type I, activating receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0005969 ! il1b-il1r1-1 direct interaction relationship: participates_in CCO:I0018039 ! il1r1-tirp physical interaction relationship: participates_in CCO:I0018686 ! traf6-map3k14-2 physical interaction relationship: participates_in CCO:I0018687 ! traf6-il1r1-1 physical interaction relationship: participates_in CCO:I0018739 ! il1r1-il1rn-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: transforms_into CCO:B0012365 ! IL1R1_HUMAN-Phosphothreonine556 [Term] id: CCO:B0005326 name: PK3CG_HUMAN def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform" [UniProtKB:P48736] synonym: "EC 2.7.1.153" EXACT [UniProtKB:P48736] synonym: "p120-PI3K" EXACT [UniProtKB:P48736] synonym: "PI3-kinase p110 subunit gamma" EXACT [UniProtKB:P48736] synonym: "PI3K" EXACT [UniProtKB:P48736] synonym: "PI3Kgamma" EXACT [UniProtKB:P48736] synonym: "PtdIns-3-kinase subunit p110" EXACT [UniProtKB:P48736] xref: EMBL:AAG61115.1 xref: EMBL:AAH35683.1 xref: EMBL:AAQ96873.1 xref: EMBL:CAA58284.1 xref: UniProtKB:P48736 xref: UniProtKB:Q8IV23 xref: UniProtKB:Q9BZC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005322 ! PIK3CG_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0006278 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: participates_in CCO:I0005970 ! hras-pik3cg-1 direct interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0005327 name: CTNB1_HUMAN def: "Catenin beta-1" [UniProtKB:P35222] synonym: "Beta-catenin" EXACT [UniProtKB:P35222] xref: EMBL:AAG35511.1 xref: EMBL:AAH58926.1 xref: EMBL:AAL89457.1 xref: EMBL:AAR18817.1 xref: EMBL:BAB93475.1 xref: EMBL:CAA61107.1 xref: EMBL:CAA79497.1 xref: UniProtKB:P35222 xref: UniProtKB:Q8NEW9 xref: UniProtKB:Q8NI94 xref: UniProtKB:Q9H391 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004417 ! CTNNB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005971 ! ctnnb1-tcf7l2-8 direct interaction relationship: participates_in CCO:I0006051 ! tcf4-ctnnb1-1 direct interaction relationship: participates_in CCO:I0006235 ! ctnnb1-tcf7l2-7 direct interaction relationship: participates_in CCO:I0006264 ! tcf7l2-parp1-5 physical interaction relationship: participates_in CCO:I0006539 ! cdh1-ctnna1-1 physical interaction relationship: participates_in CCO:I0006540 ! apc-ctbb1-1 physical interaction relationship: participates_in CCO:I0006890 ! cdc73-ctnnb1-4 physical interaction relationship: participates_in CCO:I0006912 ! tcf7l2-ctnnb1-2 physical interaction relationship: participates_in CCO:I0006913 ! tcf7l2-ctnnb1-4 physical interaction relationship: participates_in CCO:I0006999 ! cdc73-ctnnb1 physical interaction relationship: participates_in CCO:I0007011 ! tcf7l2-ctnnb1 physical interaction relationship: participates_in CCO:I0007024 ! apc-ctnnb1-3 direct interaction relationship: participates_in CCO:I0007056 ! tcf7l2-ctnnb1-7 physical interaction relationship: participates_in CCO:I0007142 ! tcf4-ctnnb1 physical interaction relationship: participates_in CCO:I0007414 ! cdc73-ctnnb1-1 physical interaction relationship: participates_in CCO:I0007415 ! cdc73-ctnnb1-2 physical interaction relationship: participates_in CCO:I0007416 ! cdc73-ctnnb1-5 physical interaction relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:I0007482 ! tcf7l2-ctnnb1-8 physical interaction relationship: participates_in CCO:I0007699 ! ctnnb1-tcf7l2-2 physical interaction relationship: participates_in CCO:I0007700 ! ctnnb1-tcf7l2-3 physical interaction relationship: participates_in CCO:I0007704 ! jup-psen1-6 physical interaction relationship: participates_in CCO:I0007705 ! tcf7l2-ctnnb1-3 physical interaction relationship: participates_in CCO:I0007790 ! cdc73-ctnnb1-3 physical interaction relationship: participates_in CCO:I0007791 ! cdc73-ctnnb1-6 physical interaction relationship: participates_in CCO:I0007792 ! cdc73-ctnnb1-7 physical interaction relationship: participates_in CCO:I0007803 ! tcf7l2-ctnnb1-1 physical interaction relationship: participates_in CCO:I0007804 ! tcf7l2-ctnnb1-5 physical interaction relationship: participates_in CCO:I0007917 ! parafibromin-ctnnb1 physical interaction relationship: participates_in CCO:I0007942 ! apc-ctnnb1-1 physical interaction relationship: participates_in CCO:I0008720 ! btrc-ctnnb1-1 physical interaction relationship: participates_in CCO:I0015862 ! ctnnb1-ctnnbip1-6 direct interaction relationship: participates_in CCO:I0017916 ! leo1-ctnnb1-5 physical interaction relationship: participates_in CCO:I0018045 ! bcl9-ctnnb1 physical interaction relationship: participates_in CCO:I0018046 ! bcl9-ctnnb1-1 physical interaction relationship: participates_in CCO:I0018095 ! ctnnb1-psen1 physical interaction relationship: participates_in CCO:I0019296 ! leo1-ctnnb1-4 physical interaction relationship: participates_in CCO:I0019309 ! ctnnb1-psen1-1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0001344 ! positive regulation of epithelial cell differentiation relationship: participates_in CCO:P0001594 ! negative regulation of chondrocyte differentiation relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0002485 ! negative regulation of osteoclast differentiation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003241 ! Wnt receptor signaling pathway through beta-catenin relationship: transforms_into CCO:B0011372 ! CTNB1_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0011373 ! CTNB1_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0011374 ! CTNB1_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0011375 ! CTNB1_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0011376 ! CTNB1_HUMAN-Phosphothreonine41 relationship: transforms_into CCO:B0011377 ! CTNB1_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: transforms_into CCO:B0011379 ! CTNB1_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0011380 ! CTNB1_HUMAN-Phosphothreonine551 relationship: transforms_into CCO:B0011381 ! CTNB1_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0011382 ! CTNB1_HUMAN-Phosphothreonine556 relationship: transforms_into CCO:B0011383 ! CTNB1_HUMAN-Phosphotyrosine654 relationship: transforms_into CCO:B0011384 ! CTNB1_HUMAN-Phosphoserine675 [Term] id: CCO:B0005328 name: NOGG_HUMAN def: "Noggin precursor" [UniProtKB:Q13253] xref: EMBL:AAA83259.1 xref: EMBL:AAH34027.1 xref: UniProtKB:Q13253 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005203 ! NOG_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0005973 ! bmp7-nog-1 direct interaction relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:B0005329 name: UBC12_HUMAN def: "NEDD8-conjugating enzyme Ubc12" [UniProtKB:P61081] synonym: "EC 6.3.2.-" EXACT [UniProtKB:P61081] synonym: "NEDD8 carrier protein" EXACT [UniProtKB:P61081] synonym: "NEDD8 protein ligase" EXACT [UniProtKB:P61081] synonym: "Ubiquitin-conjugating enzyme E2 M" EXACT [UniProtKB:P61081] xref: EMBL:AAC26141.1 xref: EMBL:AAH58924.1 xref: EMBL:AAP35400.1 xref: EMBL:BAA33145.1 xref: UniProtKB:O76069 xref: UniProtKB:P61081 xref: UniProtKB:Q8VC50 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005857 ! UBE2M_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005974 ! ube1c-ube2m-1 direct interaction relationship: participates_in CCO:I0005976 ! nedd8-tp53-1 neddylation relationship: transforms_into CCO:B0071666 ! UBC12_HUMAN-Phosphoserine50 [Term] id: CCO:B0005330 name: ZO1_HUMAN def: "Tight junction protein ZO-1" [UniProtKB:Q07157] synonym: "Tight junction protein 1" EXACT [UniProtKB:Q07157] synonym: "Zona occludens protein 1" EXACT [UniProtKB:Q07157] synonym: "Zonula occludens protein 1" EXACT [UniProtKB:Q07157] xref: EMBL:AAA02891.1 xref: EMBL:AAI11713.1 xref: EMBL:AAY22179.1 xref: UniProtKB:Q07157 xref: UniProtKB:Q2NKP3 xref: UniProtKB:Q4ZGJ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005972 ! TJP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005975 ! zo_1-actn4 physical interaction relationship: participates_in CCO:I0006453 ! zo_1-actn4-1 physical interaction relationship: participates_in CCO:I0007313 ! zo_1-actn4-7 colocalization relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007505 ! zo_1-actn4-6 physical interaction relationship: participates_in CCO:I0018755 ! zo_1-cx43 physical interaction relationship: transforms_into CCO:B0014750 ! ZO1_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0014751 ! ZO1_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0014752 ! ZO1_HUMAN-Phosphoserine175 relationship: transforms_into CCO:B0014753 ! ZO1_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0014754 ! ZO1_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0014755 ! ZO1_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0014756 ! ZO1_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0014757 ! ZO1_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0014758 ! ZO1_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0014760 ! ZO1_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0014761 ! ZO1_HUMAN-Phosphoserine617 relationship: transforms_into CCO:B0014762 ! ZO1_HUMAN-Phosphothreonine868 relationship: transforms_into CCO:B0014763 ! ZO1_HUMAN-Phosphoserine1366 relationship: transforms_into CCO:B0072260 ! ZO1_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0072261 ! ZO1_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0072262 ! ZO1_HUMAN-Phosphotyrosine132 relationship: transforms_into CCO:B0072263 ! ZO1_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0072264 ! ZO1_HUMAN-Phosphoserine912 relationship: transforms_into CCO:B0072265 ! ZO1_HUMAN-Phosphoserine927 relationship: transforms_into CCO:B0072266 ! ZO1_HUMAN-Phosphoserine968 relationship: transforms_into CCO:B0072267 ! ZO1_HUMAN-Phosphotyrosine1140 relationship: transforms_into CCO:B0072268 ! ZO1_HUMAN-Phosphotyrosine1354 relationship: transforms_into CCO:B0072269 ! ZO1_HUMAN-Phosphoserine1545 relationship: transforms_into CCO:B0072270 ! ZO1_HUMAN-Phosphoserine1617 relationship: transforms_into CCO:B0072271 ! ZO1_HUMAN-Phosphoserine1619 [Term] id: CCO:B0005331 name: NEDD8_HUMAN def: "NEDD8 precursor" [UniProtKB:Q15843] synonym: "NEDD-8" EXACT [UniProtKB:Q15843] synonym: "Neddylin" EXACT [UniProtKB:Q15843] synonym: "Neural precursor cell expressed developmentally down-regulated protein 8" EXACT [UniProtKB:Q15843] synonym: "Ubiquitin-like protein Nedd8" EXACT [UniProtKB:Q15843] xref: EMBL:AAI04201.1 xref: EMBL:AAI04202.1 xref: EMBL:AAI04665.1 xref: EMBL:BAA04889.1 xref: EMBL:CAG28590.1 xref: UniProtKB:Q15843 xref: UniProtKB:Q3SXN8 xref: UniProtKB:Q6LES6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005173 ! NEDD8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005976 ! nedd8-tp53-1 neddylation relationship: participates_in CCO:I0007022 ! appbp1-nedd8-1 physical interaction relationship: participates_in CCO:I0007023 ! appbp1-nedd8-2 physical interaction [Term] id: CCO:B0005332 name: FBX11_HUMAN def: "F-box only protein 11" [UniProtKB:Q86XK2] synonym: "VIT-1" EXACT [UniProtKB:Q86XK2] synonym: "Vitiligo-associated protein 1" EXACT [UniProtKB:Q86XK2] xref: EMBL:AAF04520.1 xref: EMBL:AAF17611.1 xref: EMBL:AAF76888.1 xref: EMBL:AAH12728.2 xref: EMBL:AAH43258.2 xref: EMBL:AAN76518.1 xref: EMBL:AAV87312.1 xref: EMBL:AAY24083.1 xref: EMBL:BAB14214.1 xref: EMBL:BAB15143.1 xref: EMBL:BAD97312.1 xref: EMBL:CAB56019.1 xref: UniProtKB:Q52ZP1 xref: UniProtKB:Q53EP7 xref: UniProtKB:Q53RT5 xref: UniProtKB:Q86XK2 xref: UniProtKB:Q8IXG3 xref: UniProtKB:Q96E90 xref: UniProtKB:Q9H6V8 xref: UniProtKB:Q9H9L1 xref: UniProtKB:Q9NR14 xref: UniProtKB:Q9UFK1 xref: UniProtKB:Q9UHI1 xref: UniProtKB:Q9UKC2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004621 ! FBXO11_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001930 ! histone-arginine N-methyltransferase activity relationship: has_function CCO:F0005577 ! peptidyl-arginine C-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005976 ! nedd8-tp53-1 neddylation relationship: participates_in CCO:I0006246 ! tp53-fbxo11-3 physical interaction relationship: participates_in CCO:I0006780 ! tp53-fbxo11-2 direct interaction relationship: participates_in CCO:I0007835 ! tp53-fbxo11-1 physical interaction relationship: participates_in CCO:I0007943 ! fbxo11-skp1-1 physical interaction [Term] id: CCO:B0005333 name: HSPB9_HUMAN def: "Heat shock protein beta-9" [UniProtKB:Q9BQS6] synonym: "Cancer/testis antigen 51" EXACT [UniProtKB:Q9BQS6] synonym: "CT51" EXACT [UniProtKB:Q9BQS6] synonym: "HspB9" EXACT [UniProtKB:Q9BQS6] xref: EMBL:AAH93991.1 xref: EMBL:AAH93993.1 xref: EMBL:CAC35727.1 xref: UniProtKB:Q52LB4 xref: UniProtKB:Q9BQS6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004841 ! HSPB9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005977 ! hspb9-ctcf physical interaction [Term] id: CCO:B0005334 name: UBE3A_HUMAN def: "Ubiquitin-protein ligase E3A" [UniProtKB:Q05086] synonym: "E6AP ubiquitin-protein ligase" EXACT [UniProtKB:Q05086] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q05086] synonym: "Human papillomavirus E6-associated protein" EXACT [UniProtKB:Q05086] synonym: "Oncogenic protein-associated protein E6-AP" EXACT [UniProtKB:Q05086] synonym: "Renal carcinoma antigen NY-REN-54" EXACT [UniProtKB:Q05086] xref: EMBL:AAA35542.1 xref: EMBL:AAB49301.1 xref: EMBL:AAB69154.1 xref: EMBL:CAA04534.1 xref: EMBL:CAA04535.1 xref: EMBL:CAA04536.1 xref: EMBL:CAA04537.1 xref: EMBL:CAA04538.1 xref: EMBL:CAA04539.1 xref: EMBL:CAA66653.1 xref: EMBL:CAA66654.1 xref: EMBL:CAA66655.1 xref: EMBL:CAA66656.1 xref: UniProtKB:P78355 xref: UniProtKB:Q05086 xref: UniProtKB:Q93066 xref: UniProtKB:Q9UEP4 xref: UniProtKB:Q9UEP5 xref: UniProtKB:Q9UEP6 xref: UniProtKB:Q9UEP7 xref: UniProtKB:Q9UEP8 xref: UniProtKB:Q9UEP9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005862 ! UBE3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005978 ! e6-e6ap-tp53 physical interaction relationship: participates_in CCO:I0005979 ! e6ap-tp53 physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0017592 ! rara-ube3a physical interaction relationship: transforms_into CCO:B0014564 ! UBE3A_HUMAN-Phosphoserine218 [Term] id: CCO:B0005335 name: SNIP1_HUMAN def: "Smad nuclear-interacting protein 1" [UniProtKB:Q8TAD8] xref: EMBL:AAH27040.1 xref: EMBL:AAL91140.1 xref: EMBL:BAB14134.1 xref: EMBL:BAB55241.1 xref: UniProtKB:Q8TAD8 xref: UniProtKB:Q96SP9 xref: UniProtKB:Q9H9T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005645 ! SNIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005980 ! snip1-myc-2 physical interaction relationship: participates_in CCO:I0005981 ! myc-snip1-1 physical interaction relationship: participates_in CCO:I0005983 ! snip1-myc-4 physical interaction relationship: participates_in CCO:I0006463 ! snip1-myc-1 physical interaction relationship: participates_in CCO:I0006607 ! snip1-myc physical interaction relationship: participates_in CCO:I0006784 ! myc-snip1 physical interaction relationship: participates_in CCO:I0006934 ! snip1-myc-3 physical interaction relationship: participates_in CCO:I0006935 ! myc-snip1-2 physical interaction relationship: participates_in CCO:I0007187 ! myc-snip1-3 physical interaction relationship: participates_in CCO:I0015485 ! dvl2-snip1 physical interaction relationship: participates_in CCO:I0015883 ! max-snip1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0014137 ! SNIP1_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0014138 ! SNIP1_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0014139 ! SNIP1_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0014140 ! SNIP1_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0014141 ! SNIP1_HUMAN-Phosphothreonine169 relationship: transforms_into CCO:B0014142 ! SNIP1_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0014143 ! SNIP1_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0070683 ! SNIP1_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0070684 ! SNIP1_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0070685 ! SNIP1_HUMAN-Phosphoserine54 [Term] id: CCO:B0005336 name: MAX_HUMAN def: "Protein max" [UniProtKB:P61244] synonym: "Myc-associated factor X" EXACT [UniProtKB:P61244] xref: EMBL:AAA36200.1 xref: EMBL:AAA36201.1 xref: EMBL:AAH03525.1 xref: EMBL:AAH04516.1 xref: EMBL:AAH27924.1 xref: EMBL:CAA42827.1 xref: EMBL:CAA47337.1 xref: EMBL:CAA47338.1 xref: UniProtKB:P25912 xref: UniProtKB:P52163 xref: UniProtKB:P61244 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005033 ! MAX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005982 ! max-myc-4 physical interaction relationship: participates_in CCO:I0007007 ! myc-max physical interaction relationship: participates_in CCO:I0015883 ! max-snip1 physical interaction relationship: participates_in CCO:I0017389 ! mycn-max-1 physical interaction relationship: participates_in CCO:I0019512 ! mycn-max-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0012794 ! MAX_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0012795 ! MAX_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0012796 ! MAX_HUMAN-N6-acetyllysine66 relationship: transforms_into CCO:B0012797 ! MAX_HUMAN-Phosphotyrosine123 relationship: transforms_into CCO:B0012798 ! MAX_HUMAN-N6-acetyllysine153 relationship: transforms_into CCO:B0012799 ! MAX_HUMAN-N6-acetyllysine154 [Term] id: CCO:B0005337 name: RAC1_HUMAN def: "Ras-related C3 botulinum toxin substrate 1 precursor" [UniProtKB:P63000] synonym: "Cell migration-inducing gene 5 protein" EXACT [UniProtKB:P63000] synonym: "p21-Rac1" EXACT [UniProtKB:P63000] synonym: "Ras-like protein TC25" EXACT [UniProtKB:P63000] xref: EMBL:AAA36537.1 xref: EMBL:AAA36544.1 xref: EMBL:AAD30547.1 xref: EMBL:AAH04247.1 xref: EMBL:AAH50687.1 xref: EMBL:AAI07749.1 xref: EMBL:AAM21111.1 xref: EMBL:AAP35785.1 xref: EMBL:AAQ16632.1 xref: EMBL:AAS07511.1 xref: EMBL:AAS07512.1 xref: EMBL:AAZ80485.1 xref: EMBL:CAA10732.1 xref: EMBL:CAA10733.6 xref: EMBL:CAB53579.5 xref: UniProtKB:O95501 xref: UniProtKB:P15154 xref: UniProtKB:P63000 xref: UniProtKB:Q3Y4D3 xref: UniProtKB:Q5JAA8 xref: UniProtKB:Q9BTB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005411 ! RAC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005993 ! pard6a-rac1-2 physical interaction relationship: participates_in CCO:I0005995 ! pard6b-rac1-1 physical interaction relationship: participates_in CCO:I0005997 ! pard6g-rac1-1 physical interaction relationship: participates_in CCO:I0006835 ! rac1-pard6a-1 physical interaction relationship: participates_in CCO:I0006836 ! rac1-pard6b-1 physical interaction relationship: participates_in CCO:I0006837 ! rac1-pard6g-1 physical interaction relationship: participates_in CCO:I0006838 ! pard6b-rac1-2 physical interaction relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007063 ! rac1-pard6b-2 physical interaction relationship: participates_in CCO:I0015886 ! prcki-rac1-1 physical interaction relationship: participates_in CCO:I0016004 ! arhgdia-rac1-1 direct interaction relationship: participates_in CCO:I0016243 ! rac1-ncf2-2 physical interaction relationship: participates_in CCO:I0017511 ! rac1-arfaptin2 direct interaction relationship: participates_in CCO:I0017771 ! arhgap24-rac1-1 physical interaction relationship: participates_in CCO:I0017859 ! rac1-dock1-3 physical interaction relationship: participates_in CCO:I0018170 ! rac1-pak1-4 direct interaction relationship: participates_in CCO:I0018171 ! rac1-ncf2-3 direct interaction relationship: participates_in CCO:I0018197 ! rac1-arfip2-2 physical interaction relationship: participates_in CCO:I0018296 ! rac1-elmo1-1 physical interaction relationship: participates_in CCO:I0018297 ! rac1-dock-1 physical interaction relationship: participates_in CCO:I0018331 ! rac1-arfip2-3 physical interaction relationship: participates_in CCO:I0018591 ! rac1-dock1-4 physical interaction relationship: participates_in CCO:I0018592 ! rac1-dock2-1 physical interaction relationship: participates_in CCO:I0018651 ! rac1-arfip2 physical interaction relationship: participates_in CCO:I0018662 ! rac1-arfip2-1 physical interaction relationship: participates_in CCO:I0018745 ! arfip2-rac1-1 direct interaction relationship: participates_in CCO:I0018746 ! arfip2-rac1-2 direct interaction relationship: participates_in CCO:I0018747 ! arfip2-rac1-3 direct interaction relationship: participates_in CCO:I0019234 ! rac1-dock1-1 physical interaction relationship: participates_in CCO:I0019235 ! rac1-dock1-2 physical interaction relationship: participates_in CCO:I0019238 ! rac1-dock1-5 physical interaction relationship: participates_in CCO:I0019239 ! rac1-dock1-6 physical interaction relationship: participates_in CCO:I0019351 ! rac1-pak1-3 direct interaction relationship: participates_in CCO:I0020395 ! park2-rac1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000922 ! regulation of hydrogen peroxide metabolic process relationship: participates_in CCO:P0001987 ! positive regulation of Rho protein signal transduction relationship: participates_in CCO:P0002803 ! negative regulation of receptor-mediated endocytosis relationship: transforms_into CCO:B0013659 ! RAC1_HUMAN-ADP-ribosylasparagine39 relationship: transforms_into CCO:B0013660 ! RAC1_HUMAN-Cysteine methyl ester189 [Term] id: CCO:B0005338 name: CDC42_HUMAN def: "Cell division control protein 42 homolog precursor" [UniProtKB:P60953] synonym: "G25K GTP-binding protein" EXACT [UniProtKB:P60953] xref: EMBL:AAA52494.1 xref: EMBL:AAA52592.1 xref: EMBL:AAH02711.1 xref: EMBL:AAH03682.1 xref: EMBL:AAH18266.1 xref: EMBL:AAM21109.1 xref: EMBL:AAM21110.1 xref: EMBL:AAT70721.1 xref: EMBL:CAB52602.1 xref: EMBL:CAB57325.1 xref: EMBL:CAB57326.1 xref: EMBL:CAD92551.1 xref: UniProtKB:P21181 xref: UniProtKB:P25763 xref: UniProtKB:P60953 xref: UniProtKB:Q7L8R5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004290 ! CDC42_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000989 ! filopodium relationship: participates_in CCO:I0005994 ! pard6a-cdc42-4 physical interaction relationship: participates_in CCO:I0005996 ! pard6b-cdc42-4 physical interaction relationship: participates_in CCO:I0005998 ! pard6g-cdc42-1 physical interaction relationship: participates_in CCO:I0006632 ! pard6a-cdc42-2 physical interaction relationship: participates_in CCO:I0006634 ! pard6a-cdc42-3 physical interaction relationship: participates_in CCO:I0006832 ! cdc42-pard6a-1 physical interaction relationship: participates_in CCO:I0006833 ! cdc42-pard6b-1 physical interaction relationship: participates_in CCO:I0006834 ! cdc42-pard6g-1 physical interaction relationship: participates_in CCO:I0006839 ! pard6b-cdc42-5 physical interaction relationship: participates_in CCO:I0007064 ! cdc42-pard6b-2 physical interaction relationship: participates_in CCO:I0007205 ! pard6a-cdc42-5 physical interaction relationship: participates_in CCO:I0007224 ! cdc42-pard6a-2 physical interaction relationship: participates_in CCO:I0007225 ! pard6b-cdc42-6 physical interaction relationship: participates_in CCO:I0007226 ! cdc42-pard6b-3 physical interaction relationship: participates_in CCO:I0007606 ! wasl-lck-2 phosphorylation relationship: participates_in CCO:I0008002 ! cdc42-rif1 physical interaction relationship: participates_in CCO:I0008003 ! cdc42-tp53 physical interaction relationship: participates_in CCO:I0015213 ! cdc42-cdc42ep1 physical interaction relationship: participates_in CCO:I0015887 ! prkci-cdc42-1 physical interaction relationship: participates_in CCO:I0015901 ! cdc42-iqgap1-2 physical interaction relationship: participates_in CCO:I0016236 ! cdc42-was-5 physical interaction relationship: participates_in CCO:I0016242 ! cdc42-ncf2-1 physical interaction relationship: participates_in CCO:I0016278 ! wasp-cdc42-1 direct interaction relationship: participates_in CCO:I0017744 ! cdc42-arhgap1-1 direct interaction relationship: participates_in CCO:I0017756 ! cdc42bpg -cdc42-1 physical interaction relationship: participates_in CCO:I0017757 ! cdc42bpa -cdc42-1 physical interaction relationship: participates_in CCO:I0017770 ! arhgap24-cdc42-1 physical interaction relationship: participates_in CCO:I0018006 ! cdc42-was-8 physical interaction relationship: participates_in CCO:I0018071 ! cdc42bpa-cdc42-2 direct interaction relationship: participates_in CCO:I0018072 ! cdc42bpa-cdc42-3 direct interaction relationship: participates_in CCO:I0018292 ! prkci-cdc42-2 physical interaction relationship: participates_in CCO:I0018293 ! cdc42-prkci-1 physical interaction relationship: participates_in CCO:I0018481 ! cdc42-was-2 direct interaction relationship: participates_in CCO:I0018507 ! cdc42bpa-cdc42-1 direct interaction relationship: participates_in CCO:I0018825 ! cdc42-itsn1-2 physical interaction relationship: participates_in CCO:I0018880 ! wasl-ptpn2-2 phosphorylation relationship: participates_in CCO:I0019181 ! arhgap1-cdc42-1 direct interaction relationship: participates_in CCO:I0019236 ! cdc42-was-1 physical interaction relationship: participates_in CCO:I0019237 ! cdc42-was-3 physical interaction relationship: participates_in CCO:I0019253 ! cdc42-itsn1-1 direct interaction relationship: participates_in CCO:I0019346 ! cdc42-was-4 direct interaction relationship: participates_in CCO:I0019347 ! cdc42-iqgap1-1 physical interaction relationship: participates_in CCO:I0019350 ! cdc42-was-6 physical interaction relationship: participates_in CCO:I0019383 ! cdc42-pak1-6 physical interaction relationship: participates_in CCO:I0019531 ! cdc42-eef1g physical interaction relationship: participates_in CCO:I0019532 ! cdc42-unc119 physical interaction relationship: participates_in CCO:I0019688 ! cdc42-c14orf1 physical interaction relationship: participates_in CCO:I0019689 ! cdc42-pde6d physical interaction relationship: participates_in CCO:I0019690 ! cdc42-ubr1 physical interaction relationship: participates_in CCO:I0019943 ! cdc42-htatip physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001391 ! positive regulation of pseudopodium formation relationship: participates_in CCO:P0001413 ! negative regulation of protein complex assembly relationship: transforms_into CCO:B0011083 ! CDC42_HUMAN-Cysteine methyl ester188 [Term] id: CCO:B0005339 name: CBP_HUMAN def: "CREB-binding protein" [UniProtKB:Q92793] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q92793] xref: EMBL:AAC51331.2 xref: EMBL:AAC51339.1 xref: EMBL:AAC51340.1 xref: EMBL:AAC51770.1 xref: UniProtKB:O00147 xref: UniProtKB:Q16376 xref: UniProtKB:Q92793 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004230 ! CREBBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006000 ! daxx-crebbp-1 physical interaction relationship: participates_in CCO:I0006001 ! crebbp-pax5-1 physical interaction relationship: participates_in CCO:I0006713 ! crebbp-khdrbs1-9 colocalization relationship: participates_in CCO:I0006857 ! p53-crebbp-6 physical interaction relationship: participates_in CCO:I0007083 ! p53-crebbp-2 physical interaction relationship: participates_in CCO:I0007084 ! p53-crebbp-3 physical interaction relationship: participates_in CCO:I0007085 ! p53-crebbp-4 physical interaction relationship: participates_in CCO:I0007086 ! p53-crebbp-5 physical interaction relationship: participates_in CCO:I0007150 ! cbp-atf3 physical interaction relationship: participates_in CCO:I0007185 ! cbp-stat5a-1 physical interaction relationship: participates_in CCO:I0007186 ! cbp-stat5b-1 physical interaction relationship: participates_in CCO:I0007242 ! p53-crebbp-1 physical interaction relationship: participates_in CCO:I0015969 ! crebbp-nap1l1-2 direct interaction relationship: participates_in CCO:I0017661 ! ncoa6-crebbp-1 physical interaction relationship: participates_in CCO:I0017739 ! crebbp-nap1l1 physical interaction relationship: participates_in CCO:I0018211 ! ncoa3-crebbp-ncoa2-1 physical interaction relationship: participates_in CCO:I0018213 ! ncoa1-ncoa2-crebbp physical interaction relationship: participates_in CCO:I0018305 ! hd-crebbp-1 physical interaction relationship: participates_in CCO:I0018557 ! rela-cbp direct interaction relationship: participates_in CCO:I0018558 ! rela-cbp-1 physical interaction relationship: participates_in CCO:I0019290 ! crebbp-nap1l1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0010953 ! CBP_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0010954 ! CBP_HUMAN-Omega-N-methylated arginine601 relationship: transforms_into CCO:B0010955 ! CBP_HUMAN-Omega-N-methylated arginine625 relationship: transforms_into CCO:B0010956 ! CBP_HUMAN-Phosphothreonine1001 relationship: transforms_into CCO:B0010957 ! CBP_HUMAN-Phosphoserine1030 relationship: transforms_into CCO:B0010958 ! CBP_HUMAN-Phosphoserine1072 relationship: transforms_into CCO:B0010959 ! CBP_HUMAN-N6-acetyllysine1588 relationship: transforms_into CCO:B0010960 ! CBP_HUMAN-N6-acetyllysine1591 relationship: transforms_into CCO:B0010961 ! CBP_HUMAN-N6-acetyllysine1592 relationship: transforms_into CCO:B0010962 ! CBP_HUMAN-N6-acetyllysine1595 relationship: transforms_into CCO:B0010963 ! CBP_HUMAN-N6-acetyllysine1597 relationship: transforms_into CCO:B0010964 ! CBP_HUMAN-Phosphoserine1755 relationship: transforms_into CCO:B0064094 ! CBP_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0064095 ! CBP_HUMAN-Phosphoserine2063 relationship: transforms_into CCO:B0064096 ! CBP_HUMAN-Phosphoserine2076 relationship: transforms_into CCO:B0064097 ! CBP_HUMAN-Phosphoserine2079 [Term] id: CCO:B0005340 name: PAX5_HUMAN def: "Paired box protein Pax-5" [UniProtKB:Q02548] synonym: "B-cell-specific transcription factor" EXACT [UniProtKB:Q02548] synonym: "BSAP" EXACT [UniProtKB:Q02548] xref: EMBL:AAA58397.1 xref: EMBL:AAC35286.1 xref: EMBL:ABI30005.1 xref: EMBL:ABI33104.1 xref: EMBL:ABI33105.1 xref: UniProtKB:A3QVP6 xref: UniProtKB:A3QVP7 xref: UniProtKB:A3QVP8 xref: UniProtKB:O75933 xref: UniProtKB:Q02548 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005270 ! PAX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006001 ! crebbp-pax5-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005341 name: HDA10_HUMAN def: "Histone deacetylase 10" [UniProtKB:Q969S8] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q969S8] synonym: "HD10" EXACT [UniProtKB:Q969S8] xref: EMBL:AAI25084.1 xref: EMBL:AAK84023.1 xref: EMBL:AAK92205.1 xref: EMBL:AAK92206.1 xref: EMBL:AAL30513.1 xref: EMBL:AAS48345.1 xref: EMBL:CAB63048.1 xref: EMBL:CAC21653.2 xref: EMBL:CAG30351.1 xref: UniProtKB:Q08AP4 xref: UniProtKB:Q6STF9 xref: UniProtKB:Q969S8 xref: UniProtKB:Q96P77 xref: UniProtKB:Q96P78 xref: UniProtKB:Q9H028 xref: UniProtKB:Q9UGX1 xref: UniProtKB:Q9UGX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004784 ! HDAC10_human relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006003 ! hdac10-hdac3-1 physical interaction relationship: participates_in CCO:I0017663 ! hdac2-hdac10-1 physical interaction relationship: participates_in CCO:I0017664 ! ncor2-hdac10-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005342 name: DEK_HUMAN def: "Protein DEK" [UniProtKB:P35659] xref: EMBL:AAH35259.1 xref: EMBL:CAA45536.1 xref: EMBL:CAI20082.2 xref: UniProtKB:P35659 xref: UniProtKB:Q5TGV4 xref: UniProtKB:Q5TGV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004464 ! DEK_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006004 ! daxx-dek-1 physical interaction relationship: participates_in CCO:I0006949 ! dek-daxx-1 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0011487 ! DEK_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0011488 ! DEK_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0011489 ! DEK_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0011490 ! DEK_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0011491 ! DEK_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0011492 ! DEK_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0011493 ! DEK_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0011494 ! DEK_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0011495 ! DEK_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0011496 ! DEK_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0011497 ! DEK_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0011498 ! DEK_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0011499 ! DEK_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0011500 ! DEK_HUMAN-Phosphoserine307 [Term] id: CCO:B0005343 name: HDAC2_HUMAN def: "Histone deacetylase 2" [UniProtKB:Q92769] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q92769] synonym: "HD2" EXACT [UniProtKB:Q92769] xref: EMBL:AAC50814.1 xref: EMBL:AAH31055.2 xref: EMBL:CAI14206.1 xref: EMBL:CAI14207.1 xref: EMBL:CAI15363.1 xref: UniProtKB:Q5SRI8 xref: UniProtKB:Q5SZ86 xref: UniProtKB:Q8NEH4 xref: UniProtKB:Q92769 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004787 ! HDAC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006004 ! daxx-dek-1 physical interaction relationship: participates_in CCO:I0006005 ! daxx-hdac-1 physical interaction relationship: participates_in CCO:I0006303 ! hcfc1-hdac2-1 physical interaction relationship: participates_in CCO:I0006822 ! brms1-hdac2 physical interaction relationship: participates_in CCO:I0006949 ! dek-daxx-1 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007190 ! hdac2-brms1 physical interaction relationship: participates_in CCO:I0007459 ! suv39h1-hdac2-3 physical interaction relationship: participates_in CCO:I0007916 ! pa2g4-hdac2-1 physical interaction relationship: participates_in CCO:I0007977 ! suv93h1-hdac2-1 physical interaction relationship: participates_in CCO:I0007978 ! suv93h1-hdac2-2 physical interaction relationship: participates_in CCO:I0017660 ! hdac1-hdac2-1 physical interaction relationship: participates_in CCO:I0017663 ! hdac2-hdac10-1 physical interaction relationship: participates_in CCO:I0018322 ! hdac2-cir-1 physical interaction relationship: participates_in CCO:I0018538 ! hdac1-rcor1 physical interaction relationship: participates_in CCO:I0018539 ! hdac1-smarce1 physical interaction relationship: participates_in CCO:I0018540 ! hdac1-smarca4 physical interaction relationship: participates_in CCO:I0018541 ! hdac1-smarcc2 physical interaction relationship: participates_in CCO:I0018640 ! hdac2-rfx5 physical interaction relationship: participates_in CCO:I0018641 ! hdac2-rfx5-1 physical interaction relationship: participates_in CCO:I0018700 ! mbd1-hdac2-3 physical interaction relationship: participates_in CCO:I0018729 ! eed-hdac1 physical interaction relationship: participates_in CCO:I0019387 ! hdac1-hdac2-2 physical interaction relationship: participates_in CCO:I0019456 ! hdac2-rfx5-2 physical interaction relationship: participates_in CCO:I0019457 ! hdac2-rfx5-3 physical interaction relationship: participates_in CCO:I0019523 ! mbde-hdac2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012159 ! HDAC2_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0012160 ! HDAC2_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0012161 ! HDAC2_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0012162 ! HDAC2_HUMAN-Phosphoserine424 [Term] id: CCO:B0005344 name: MARK4_HUMAN def: "MAP/microtubule affinity-regulating kinase 4" [UniProtKB:Q96L34] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q96L34] synonym: "MAP/microtubule affinity-regulating kinase-like 1" EXACT [UniProtKB:Q96L34] xref: EMBL:AAL23683.1 xref: EMBL:AAM55491.1 xref: EMBL:BAB39380.1 xref: EMBL:BAB47489.1 xref: EMBL:BAB55238.1 xref: EMBL:BAC03375.1 xref: EMBL:BAC11510.1 xref: UniProtKB:Q8NG37 xref: UniProtKB:Q96JG7 xref: UniProtKB:Q96L34 xref: UniProtKB:Q96SQ2 xref: UniProtKB:Q9BYD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005028 ! MARK4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006006 ! tubg-mark4-2 physical interaction relationship: participates_in CCO:I0006007 ! tubg-mark4-3 physical interaction relationship: participates_in CCO:I0007067 ! tubg-mark4-1 physical interaction relationship: participates_in CCO:I0007210 ! pard6a-mark4-1 physical interaction relationship: participates_in CCO:I0007217 ! stk11-mark4-1 physical interaction relationship: participates_in CCO:I0018273 ! mark4-ywhaz-3 physical interaction relationship: participates_in CCO:I0018277 ! prkci-mark4-1 physical interaction relationship: participates_in CCO:I0018279 ! ywhah-mark4-1 physical interaction relationship: participates_in CCO:I0018283 ! pnma1-mark4-1 physical interaction relationship: participates_in CCO:I0018289 ! mark4-ywhah-1 physical interaction relationship: participates_in CCO:I0018290 ! ywhaz-mark4-1 physical interaction relationship: participates_in CCO:I0018291 ! mark4-ywhaz-1 physical interaction relationship: participates_in CCO:I0020590 ! mark4-hps6 physical interaction relationship: participates_in CCO:P0002150 ! positive regulation of programmed cell death relationship: transforms_into CCO:B0012776 ! MARK4_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0012777 ! MARK4_HUMAN-Phosphothreonine214 [Term] id: CCO:B0005345 name: XPA_HUMAN def: "DNA repair protein complementing XP-A cells" [UniProtKB:P23025] synonym: "Xeroderma pigmentosum group A-complementing protein" EXACT [UniProtKB:P23025] xref: EMBL:AAB60404.1 xref: EMBL:AAH14965.1 xref: EMBL:AAM18969.1 xref: EMBL:AAV38325.1 xref: EMBL:BAA03403.1 xref: UniProtKB:P23025 xref: UniProtKB:Q6LCW7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005938 ! XPA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006011 ! rassf1-xpa physical interaction relationship: transforms_into CCO:B0014707 ! XPA_HUMAN-Phosphoserine196 [Term] id: CCO:B0005346 name: SK2L2_HUMAN def: "Superkiller viralicidic activity 2-like 2" [UniProtKB:P42285] synonym: "ATP-dependent helicase SKIV2L2" EXACT [UniProtKB:P42285] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P42285] xref: EMBL:AAH14669.2 xref: EMBL:AAH28604.3 xref: EMBL:AAH31779.1 xref: EMBL:AAH65258.1 xref: EMBL:AAI04997.1 xref: EMBL:AAI13510.1 xref: EMBL:BAA06124.2 xref: EMBL:CAE45877.1 xref: UniProtKB:P42285 xref: UniProtKB:Q2M386 xref: UniProtKB:Q6MZZ8 xref: UniProtKB:Q6P170 xref: UniProtKB:Q8N5R0 xref: UniProtKB:Q8TAG2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005618 ! SKIV2L2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0006012 ! mphosph6-kiaa0052 physical interaction relationship: participates_in CCO:I0018441 ! pbx2-kiaa0052 physical interaction [Term] id: CCO:B0005347 name: PARN_HUMAN def: "Poly(A)-specific ribonuclease PARN" [UniProtKB:O95453] synonym: "Deadenylating nuclease" EXACT [UniProtKB:O95453] synonym: "Deadenylation nuclease" EXACT [UniProtKB:O95453] synonym: "EC 3.1.13.4" EXACT [UniProtKB:O95453] synonym: "Polyadenylate-specific ribonuclease" EXACT [UniProtKB:O95453] xref: EMBL:AAH50029.1 xref: EMBL:CAA06683.1 xref: UniProtKB:O95453 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005268 ! PARN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006013 ! mphosph6-parn physical interaction relationship: transforms_into CCO:B0013398 ! PARN_HUMAN-Phosphoserine163 relationship: transforms_into CCO:B0013399 ! PARN_HUMAN-Phosphoserine557 relationship: transforms_into CCO:B0013400 ! PARN_HUMAN-Phosphoserine587 relationship: transforms_into CCO:B0013401 ! PARN_HUMAN-Phosphoserine619 [Term] id: CCO:B0005348 name: EXOSX_HUMAN def: "Exosome component 10" [UniProtKB:Q01780] synonym: "Autoantigen PM/Scl 2" EXACT [UniProtKB:Q01780] synonym: "P100 polymyositis-scleroderma overlap syndrome-associated autoantigen" EXACT [UniProtKB:Q01780] synonym: "PM/Scl-100" EXACT [UniProtKB:Q01780] synonym: "Polymyositis/scleroderma autoantigen 100 kDa" EXACT [UniProtKB:Q01780] synonym: "Polymyositis/scleroderma autoantigen 2" EXACT [UniProtKB:Q01780] xref: EMBL:AAB59352.1 xref: EMBL:AAH39901.1 xref: EMBL:AAH73788.1 xref: EMBL:CAA46904.1 xref: EMBL:CAC15569.1 xref: EMBL:CAI22106.1 xref: UniProtKB:B1AKQ1 xref: UniProtKB:Q01780 xref: UniProtKB:Q15158 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004601 ! EXOSC10_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000032 ! nuclear exosome (RNase complex) relationship: located_in CCO:C0000034 ! exosome (RNase complex) relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006014 ! mphosph6-pmscl2 physical interaction relationship: participates_in CCO:I0015892 ! xrn2-pmscl2 physical interaction relationship: participates_in CCO:I0017317 ! pmscl2-ssrp1 physical interaction relationship: participates_in CCO:I0017318 ! pmscl2-ruvbl2 physical interaction [Term] id: CCO:B0005349 name: LSM8_HUMAN def: "U6 snRNA-associated Sm-like protein LSm8" [UniProtKB:O95777] xref: EMBL:AAD15542.1 xref: EMBL:AAD56232.1 xref: EMBL:AAH02742.1 xref: EMBL:AAH22440.1 xref: UniProtKB:O95777 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004995 ! LSM8_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003545 ! U6 snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0006015 ! lsm8-rent1 physical interaction relationship: participates_in CCO:I0006497 ! lsm8-ask/h37_(hudbf4 physical interaction relationship: participates_in CCO:I0006498 ! lsm8-sept5 physical interaction relationship: participates_in CCO:I0017326 ! lsm8-ighmbp2 physical interaction relationship: participates_in CCO:I0017327 ! lsm8-gtf2i physical interaction relationship: participates_in CCO:I0017328 ! lsm8-il28ra physical interaction relationship: participates_in CCO:I0017329 ! lsm8-itsn2 physical interaction relationship: transforms_into CCO:B0012708 ! LSM8_HUMAN-N-acetylthreonine2 [Term] id: CCO:B0005350 name: TRRAP_HUMAN def: "Transformation/transcription domain-associated protein" [UniProtKB:Q9Y4A5] synonym: "350/400 kDa PCAF-associated factor" EXACT [UniProtKB:Q9Y4A5] synonym: "PAF350/400" EXACT [UniProtKB:Q9Y4A5] synonym: "STAF40" EXACT [UniProtKB:Q9Y4A5] synonym: "Tra1 homolog" EXACT [UniProtKB:Q9Y4A5] xref: EMBL:AAC27675.2 xref: EMBL:AAC62433.1 xref: EMBL:AAD04629.1 xref: EMBL:AAD09420.1 xref: UniProtKB:O75218 xref: UniProtKB:Q9Y4A5 xref: UniProtKB:Q9Y631 xref: UniProtKB:Q9Y6H4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005837 ! TRRAP_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000013 ! PCAF complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001626 ! NuA4 histone acetyltransferase complex relationship: participates_in CCO:I0006017 ! e2f1-trrap-1 physical interaction relationship: participates_in CCO:I0006018 ! e2f4-trrap-1 physical interaction relationship: participates_in CCO:I0006019 ! htatip-trrap-1 physical interaction relationship: participates_in CCO:I0006703 ! trrap-myc-2 physical interaction relationship: participates_in CCO:I0006748 ! brca1-trrap-2 physical interaction relationship: participates_in CCO:I0006749 ! brca1-trrap-3 physical interaction relationship: participates_in CCO:I0006887 ! brca1-trrap-6 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007076 ! trrap-myc-1 physical interaction relationship: participates_in CCO:I0007367 ! trrap-brca1 direct interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0007454 ! brca1-trrap physical interaction relationship: participates_in CCO:I0007455 ! brca1-trrap-1 physical interaction relationship: participates_in CCO:I0007594 ! brca1-trrap-4 direct interaction relationship: participates_in CCO:I0007595 ! brca1-trrap-5 physical interaction relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:I0015958 ! atxn7-trrap-3 physical interaction relationship: participates_in CCO:I0016129 ! atxn7-trrap-6 physical interaction relationship: participates_in CCO:I0016130 ! trrap-1-atxn7-1 physical interaction relationship: participates_in CCO:I0017346 ! c20orf20-epc1-5 physical interaction relationship: participates_in CCO:I0017762 ! atxn7-trrap-5 physical interaction relationship: participates_in CCO:I0017887 ! atxn7-trrap physical interaction relationship: participates_in CCO:I0017888 ! trrap-1-atxn7 physical interaction relationship: participates_in CCO:I0018295 ! c20orf20-epc1-3 physical interaction relationship: participates_in CCO:I0018476 ! c20orf20-epc1-1 physical interaction relationship: participates_in CCO:I0018531 ! trrap-err1 direct interaction relationship: participates_in CCO:I0018691 ! err1-trrap-1 physical interaction relationship: participates_in CCO:I0018692 ! err1-trrap-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0014538 ! TRRAP_HUMAN-Phosphoserine2051 relationship: transforms_into CCO:B0014539 ! TRRAP_HUMAN-Phosphoserine2077 [Term] id: CCO:B0005351 name: TIP60_HUMAN def: "Histone acetyltransferase HTATIP" [UniProtKB:Q92993] synonym: "60 kDa Tat interactive protein" EXACT [UniProtKB:Q92993] synonym: "cPLA(2)-interacting protein" EXACT [UniProtKB:Q92993] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q92993] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q92993] synonym: "HIV-1 Tat interactive protein" EXACT [UniProtKB:Q92993] synonym: "Tip60" EXACT [UniProtKB:Q92993] xref: EMBL:AAB02683.1 xref: EMBL:AAB18236.1 xref: EMBL:AAD00163.1 xref: EMBL:AAH00166.3 xref: EMBL:AAH64912.1 xref: EMBL:AAI17168.1 xref: EMBL:AAO21130.1 xref: UniProtKB:O95624 xref: UniProtKB:Q13430 xref: UniProtKB:Q17RW5 xref: UniProtKB:Q6GSE8 xref: UniProtKB:Q92993 xref: UniProtKB:Q9BWK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005784 ! HTATIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006019 ! htatip-trrap-1 physical interaction relationship: participates_in CCO:I0006166 ! bard1-htatip physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007576 ! htatip-dleu1-1 physical interaction relationship: participates_in CCO:I0008078 ! cct7-htatip physical interaction relationship: participates_in CCO:I0008094 ! dleu1-htatip physical interaction relationship: participates_in CCO:I0008131 ! mad2l1bp-htatip physical interaction relationship: participates_in CCO:I0016047 ! gapd-htatip physical interaction relationship: participates_in CCO:I0016092 ! gadd45g-htatip-1 physical interaction relationship: participates_in CCO:I0016093 ! kiaa1377-htatip-1 physical interaction relationship: participates_in CCO:I0018166 ! kiaa1377-htatip physical interaction relationship: participates_in CCO:I0018167 ! gadd45g-htatip physical interaction relationship: participates_in CCO:I0018295 ! c20orf20-epc1-3 physical interaction relationship: participates_in CCO:I0018476 ! c20orf20-epc1-1 physical interaction relationship: participates_in CCO:I0019191 ! htatip-atxn1 physical interaction relationship: participates_in CCO:I0019192 ! atxn1-htatip-1 physical interaction relationship: participates_in CCO:I0019406 ! ptpn4-htatip-1 physical interaction relationship: participates_in CCO:I0019573 ! trib3-htatip physical interaction relationship: participates_in CCO:I0019592 ! hnrph3-htatip physical interaction relationship: participates_in CCO:I0019616 ! sat-htatip physical interaction relationship: participates_in CCO:I0019640 ! znf24-htatip physical interaction relationship: participates_in CCO:I0019652 ! arih2-htatip physical interaction relationship: participates_in CCO:I0019670 ! bmi1-htatip physical interaction relationship: participates_in CCO:I0019679 ! c7orf20-htatip physical interaction relationship: participates_in CCO:I0019683 ! cbx8-htatip physical interaction relationship: participates_in CCO:I0019693 ! cdk5rap2-htatip physical interaction relationship: participates_in CCO:I0019701 ! cstf2-htatip physical interaction relationship: participates_in CCO:I0019727 ! gsto1-htatip physical interaction relationship: participates_in CCO:I0019745 ! ik-htatip physical interaction relationship: participates_in CCO:I0019757 ! lmna-htatip physical interaction relationship: participates_in CCO:I0019766 ! c16orf24-htatip physical interaction relationship: participates_in CCO:I0019770 ! nap1l5-htatip physical interaction relationship: participates_in CCO:I0019782 ! pdcd5-htatip physical interaction relationship: participates_in CCO:I0019790 ! pole2-htatip physical interaction relationship: participates_in CCO:I0019794 ! polr3f-htatip physical interaction relationship: participates_in CCO:I0019805 ! ptpn4-htatip physical interaction relationship: participates_in CCO:I0019806 ! ptprs-htatip physical interaction relationship: participates_in CCO:I0019838 ! snapap-htatip physical interaction relationship: participates_in CCO:I0019943 ! cdc42-htatip physical interaction relationship: participates_in CCO:I0019960 ! creld1-htatip physical interaction relationship: participates_in CCO:I0019983 ! efna1-htatip physical interaction relationship: participates_in CCO:I0020009 ! gemin7-htatip physical interaction relationship: participates_in CCO:I0020086 ! ndufv2-htatip physical interaction relationship: participates_in CCO:I0020114 ! plekha4-htatip physical interaction relationship: participates_in CCO:I0020143 ! rgl2-htatip physical interaction relationship: participates_in CCO:I0020171 ! snrpd2-htatip physical interaction relationship: participates_in CCO:I0020179 ! syn1-htatip physical interaction relationship: participates_in CCO:I0020369 ! mgc45871-htatip physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014378 ! TIP60_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0014379 ! TIP60_HUMAN-Phosphoserine90 [Term] id: CCO:B0005352 name: ORC1_HUMAN def: "Origin recognition complex subunit 1" [UniProtKB:Q13415] synonym: "Replication control protein 1" EXACT [UniProtKB:Q13415] xref: EMBL:AAA86260.1 xref: EMBL:AAC50325.1 xref: EMBL:CAI12288.1 xref: UniProtKB:Q13415 xref: UniProtKB:Q13471 xref: UniProtKB:Q5T0F5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005232 ! ORC1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006020 ! orc1-cdk2-1 physical interaction relationship: participates_in CCO:I0006021 ! orc1-orc2-1 physical interaction relationship: participates_in CCO:I0006075 ! orc1l-hscdc6 direct interaction relationship: participates_in CCO:I0006076 ! orc1l-hscdc5 direct interaction relationship: participates_in CCO:I0006077 ! orc1l-mcm5 direct interaction relationship: participates_in CCO:I0006197 ! orc1-skp2-2 physical interaction relationship: participates_in CCO:I0007537 ! orc1-skp2-1 physical interaction relationship: participates_in CCO:I0007848 ! orc1-rps27a-1 physical interaction relationship: participates_in CCO:I0016019 ! orc1l-orc5l direct interaction relationship: participates_in CCO:I0016020 ! orc1l-orc2l direct interaction relationship: participates_in CCO:I0016023 ! orc1l-orc3l direct interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: transforms_into CCO:B0013330 ! ORC1_HUMAN-Phosphoserine417 relationship: transforms_into CCO:B0013331 ! ORC1_HUMAN-Phosphoserine419 relationship: transforms_into CCO:B0013332 ! ORC1_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0013333 ! ORC1_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0068983 ! ORC1_HUMAN-Phosphoserine196 relationship: transforms_into CCO:B0068984 ! ORC1_HUMAN-Phosphothreonine203 relationship: transforms_into CCO:B0068985 ! ORC1_HUMAN-Phosphothreonine337 relationship: transforms_into CCO:B0068986 ! ORC1_HUMAN-Phosphoserine340 relationship: transforms_into CCO:B0068987 ! ORC1_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0068988 ! ORC1_HUMAN-Phosphoserine478 [Term] id: CCO:B0005353 name: ORC2_HUMAN def: "Origin recognition complex subunit 2" [UniProtKB:Q13416] xref: EMBL:AAB33970.1 xref: EMBL:AAC50326.2 xref: EMBL:AAH14834.1 xref: EMBL:AAT46690.1 xref: UniProtKB:Q13204 xref: UniProtKB:Q13416 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005233 ! ORC2L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006020 ! orc1-cdk2-1 physical interaction relationship: participates_in CCO:I0006021 ! orc1-orc2-1 physical interaction relationship: participates_in CCO:I0006084 ! mcm2-orc2l direct interaction relationship: participates_in CCO:I0006087 ! mcm10-orc2l direct interaction relationship: participates_in CCO:I0006097 ! orc2l-hscdc5 direct interaction relationship: participates_in CCO:I0006100 ! orc2l-hscdc6 direct interaction relationship: participates_in CCO:I0006150 ! orc2l-cdk2 direct interaction relationship: participates_in CCO:I0007539 ! orc2-mcm3-1 physical interaction relationship: participates_in CCO:I0007540 ! mcm3-mcm5-1 physical interaction relationship: participates_in CCO:I0007542 ! mcm4-mcm6-1 physical interaction relationship: participates_in CCO:I0016020 ! orc1l-orc2l direct interaction relationship: participates_in CCO:I0016025 ! orc2l-orc5l direct interaction relationship: participates_in CCO:I0016027 ! orc2l-orc4l direct interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: transforms_into CCO:B0068989 ! ORC2_HUMAN-Phosphothreonine116 relationship: transforms_into CCO:B0068990 ! ORC2_HUMAN-Phosphoserine280 [Term] id: CCO:B0005354 name: T2FA_HUMAN def: "General transcription factor IIF subunit 1" [UniProtKB:P35269] synonym: "General transcription factor IIF polypeptide 1 74 kDa subunit protein" EXACT [UniProtKB:P35269] synonym: "TFIIF-alpha" EXACT [UniProtKB:P35269] synonym: "Transcription initiation factor IIF subunit alpha" EXACT [UniProtKB:P35269] synonym: "Transcription initiation factor RAP74" EXACT [UniProtKB:P35269] xref: EMBL:AAH00120.1 xref: EMBL:AAH13007.1 xref: EMBL:AAP35761.1 xref: EMBL:CAA45404.1 xref: EMBL:CAA45408.1 xref: UniProtKB:P35269 xref: UniProtKB:Q9BWN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005716 ! GTF2F1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006023 ! taf1-gtf2f1-3 physical interaction relationship: participates_in CCO:I0006199 ! taf1-gtf2f1-1 physical interaction relationship: participates_in CCO:I0006200 ! taf1-gtf2f1-2 physical interaction relationship: participates_in CCO:I0008247 ! gtf2f1-ptn physical interaction relationship: participates_in CCO:I0018132 ! magec1-gtf2f1 physical interaction relationship: participates_in CCO:I0018703 ! gtf2f1-gtf2f2-1 direct interaction relationship: participates_in CCO:I0020019 ! gtf2f1-fez1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0014275 ! T2FA_HUMAN-Phosphoserine217 relationship: transforms_into CCO:B0014276 ! T2FA_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0014277 ! T2FA_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0014278 ! T2FA_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0014279 ! T2FA_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0014280 ! T2FA_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0014281 ! T2FA_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0014282 ! T2FA_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0014283 ! T2FA_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0014284 ! T2FA_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0014285 ! T2FA_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0014286 ! T2FA_HUMAN-Phosphoserine348 relationship: transforms_into CCO:B0014287 ! T2FA_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0014288 ! T2FA_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0014289 ! T2FA_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0014290 ! T2FA_HUMAN-Phosphothreonine389 relationship: transforms_into CCO:B0014291 ! T2FA_HUMAN-Phosphoserine433 [Term] id: CCO:B0005355 name: CAND1_HUMAN def: "Cullin-associated NEDD8-dissociated protein 1" [UniProtKB:Q86VP6] synonym: "Cullin-associated and neddylation-dissociated protein 1" EXACT [UniProtKB:Q86VP6] synonym: "p120 CAND1" EXACT [UniProtKB:Q86VP6] synonym: "TBP-interacting protein of 120 kDa A" EXACT [UniProtKB:Q86VP6] synonym: "TBP-interacting protein TIP120A" EXACT [UniProtKB:Q86VP6] xref: EMBL:AAF67492.1 xref: EMBL:AAH04232.1 xref: EMBL:AAH26220.1 xref: EMBL:AAH50341.1 xref: EMBL:BAA74852.2 xref: EMBL:BAB55090.1 xref: EMBL:BAB55365.1 xref: EMBL:CAB63714.1 xref: EMBL:CAB66744.1 xref: EMBL:CAD38737.1 xref: UniProtKB:O94918 xref: UniProtKB:Q6PIY4 xref: UniProtKB:Q86VP6 xref: UniProtKB:Q8NDJ4 xref: UniProtKB:Q96JZ9 xref: UniProtKB:Q96T19 xref: UniProtKB:Q9BTC4 xref: UniProtKB:Q9H0G2 xref: UniProtKB:Q9P0H7 xref: UniProtKB:Q9UF85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004218 ! CAND1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006024 ! cul1-cand1 physical interaction relationship: participates_in CCO:I0006308 ! cul1-cand1-4 physical interaction relationship: participates_in CCO:I0006309 ! cul1-cand1-5 physical interaction relationship: participates_in CCO:I0006310 ! cul1-cand1-6 physical interaction relationship: participates_in CCO:I0006682 ! cul4b-tip120a-1 physical interaction relationship: participates_in CCO:I0006683 ! cul4a-tip120a-1 physical interaction relationship: participates_in CCO:I0006684 ! cul3-tip120a-2 physical interaction relationship: participates_in CCO:I0006685 ! cul1-tip120a-1 physical interaction relationship: participates_in CCO:I0006686 ! cul2-tip120a-2 physical interaction relationship: participates_in CCO:I0006687 ! cul4b-tip120a-2 physical interaction relationship: participates_in CCO:I0006688 ! cul1-tip120a-2 physical interaction relationship: participates_in CCO:I0006689 ! cul2-tip120a-1 physical interaction relationship: participates_in CCO:I0006690 ! cul3-tip120a-1 physical interaction relationship: participates_in CCO:I0006691 ! cul4a-tip120a-2 physical interaction relationship: participates_in CCO:I0006692 ! cul4b-tip120a-3 physical interaction relationship: participates_in CCO:I0006693 ! cul1-tip120a-3 physical interaction relationship: participates_in CCO:I0006694 ! cul1-tip120a-4 physical interaction relationship: participates_in CCO:I0006865 ! cand1-cul1-3 physical interaction relationship: participates_in CCO:I0006866 ! cul1-cand1-7 physical interaction relationship: participates_in CCO:I0007103 ! cul2-cand1 physical interaction relationship: participates_in CCO:I0007104 ! cul4a-cand1 physical interaction relationship: participates_in CCO:I0007106 ! cul1-cand1-1 physical interaction relationship: participates_in CCO:I0007107 ! cand1-cul1 physical interaction relationship: participates_in CCO:I0007108 ! cand1-cul1-1 physical interaction relationship: participates_in CCO:I0007109 ! cul1-cand1-2 physical interaction relationship: participates_in CCO:I0007113 ! cand1-cul1-4 physical interaction relationship: participates_in CCO:I0007114 ! cul1-cand1-8 physical interaction relationship: participates_in CCO:I0007254 ! cand1-cul1-2 physical interaction relationship: participates_in CCO:I0007504 ! cand1-cul1-5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035989 ! CAND1_HUMAN-Phosphothreonine624 [Term] id: CCO:B0005356 name: ANDR_HUMAN def: "Androgen receptor" [UniProtKB:P10275] synonym: "Dihydrotestosterone receptor" EXACT [UniProtKB:P10275] synonym: "Nuclear receptor subfamily 3 group C member 4" EXACT [UniProtKB:P10275] xref: EMBL:AAA51729.1 xref: EMBL:AAA51770.1 xref: EMBL:AAA51771.1 xref: EMBL:AAA51772.1 xref: EMBL:AAA51774.1 xref: EMBL:AAA51775.1 xref: EMBL:AAA51780.1 xref: EMBL:AAA51886.1 xref: EMBL:AAB21256.2 xref: EMBL:AAB21257.2 xref: EMBL:AAB60346.1 xref: EMBL:AAI32976.1 xref: UniProtKB:A2RUN2 xref: UniProtKB:P10275 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004058 ! AR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006025 ! daxx-ar-1 physical interaction relationship: participates_in CCO:I0006026 ! daxx-ar-2 physical interaction relationship: participates_in CCO:I0007144 ! pa2g4-ar-1 physical interaction relationship: participates_in CCO:I0007745 ! daxx-ar-4 physical interaction relationship: participates_in CCO:I0007746 ! daxx-ar-5 physical interaction relationship: participates_in CCO:I0007868 ! daxx-ar-3 physical interaction relationship: participates_in CCO:I0017273 ! ar-myst2-1 physical interaction relationship: participates_in CCO:I0017802 ! ar-myst2-2 direct interaction relationship: participates_in CCO:I0017803 ! myst2-ar direct interaction relationship: participates_in CCO:I0017971 ! ar-myst2 physical interaction relationship: participates_in CCO:I0018751 ! ar-ncoa4-1 direct interaction relationship: participates_in CCO:I0018752 ! ar-ncoa2-2 direct interaction relationship: participates_in CCO:I0018753 ! ar-ncoa2-3 direct interaction relationship: participates_in CCO:I0018757 ! myst2-ar-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0026337 ! ANDR_HUMAN-Phosphotyrosine223 relationship: transforms_into CCO:B0026338 ! ANDR_HUMAN-Phosphotyrosine267 relationship: transforms_into CCO:B0026339 ! ANDR_HUMAN-Phosphotyrosine307 relationship: transforms_into CCO:B0026340 ! ANDR_HUMAN-Phosphotyrosine346 relationship: transforms_into CCO:B0026341 ! ANDR_HUMAN-Phosphotyrosine357 relationship: transforms_into CCO:B0026342 ! ANDR_HUMAN-Phosphotyrosine362 relationship: transforms_into CCO:B0026343 ! ANDR_HUMAN-Phosphotyrosine363 relationship: transforms_into CCO:B0026344 ! ANDR_HUMAN-Phosphotyrosine393 relationship: transforms_into CCO:B0026345 ! ANDR_HUMAN-Phosphotyrosine534 relationship: transforms_into CCO:B0026346 ! ANDR_HUMAN-Phosphotyrosine551 relationship: transforms_into CCO:B0026347 ! ANDR_HUMAN-Phosphotyrosine915 [Term] id: CCO:B0005357 name: SIN3A_HUMAN def: "Paired amphipathic helix protein Sin3a" [UniProtKB:Q96ST3] synonym: "Histone deacetylase complex subunit Sin3a" EXACT [UniProtKB:Q96ST3] synonym: "Transcriptional corepressor Sin3a" EXACT [UniProtKB:Q96ST3] xref: EMBL:AAH18973.1 xref: EMBL:AAK95854.1 xref: EMBL:AAP97288.1 xref: EMBL:BAB55197.1 xref: EMBL:BAC04801.1 xref: EMBL:BAC11280.1 xref: EMBL:CAB55972.1 xref: UniProtKB:Q8N8N4 xref: UniProtKB:Q8NC83 xref: UniProtKB:Q8WV18 xref: UniProtKB:Q96L98 xref: UniProtKB:Q96ST3 xref: UniProtKB:Q9UFQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005614 ! SIN3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006030 ! hcfc1-many-4 physical interaction relationship: participates_in CCO:I0006612 ! p53-sin3a-2 physical interaction relationship: participates_in CCO:I0006972 ! hcfc1-many-3 physical interaction relationship: participates_in CCO:I0007095 ! hcfc1-sin3a-1 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007243 ! p53-sin3a-1 physical interaction relationship: participates_in CCO:I0007251 ! hcfc1-sin3a-2 physical interaction relationship: participates_in CCO:I0007355 ! hcfc1-many-2 physical interaction relationship: participates_in CCO:I0007561 ! hcfc1-sin3a-3 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0017979 ! ski-sin3a-1 physical interaction relationship: participates_in CCO:I0018056 ! sin3a-sfpq-1 physical interaction relationship: participates_in CCO:I0018281 ! dach-sin3a-1 physical interaction relationship: participates_in CCO:I0018306 ! hd-crebbp-2 physical interaction relationship: participates_in CCO:I0019252 ! sin3a-sfpq-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014060 ! SIN3A_HUMAN-Phosphoserine832 relationship: transforms_into CCO:B0014061 ! SIN3A_HUMAN-Phosphoserine860 relationship: transforms_into CCO:B0014062 ! SIN3A_HUMAN-Phosphoserine1112 relationship: transforms_into CCO:B0070535 ! SIN3A_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0070536 ! SIN3A_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0070537 ! SIN3A_HUMAN-Phosphoserine940 [Term] id: CCO:B0005358 name: WRN_HUMAN def: "Werner syndrome ATP-dependent helicase" [UniProtKB:Q14191] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q14191] xref: EMBL:AAC41981.1 xref: EMBL:AAC63361.1 xref: EMBL:AAF06162.1 xref: EMBL:AAR05448.1 xref: UniProtKB:Q14191 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005933 ! WRN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006032 ! wrn-rad52-9 colocalization relationship: participates_in CCO:I0006033 ! wrn-p53-3 colocalization relationship: participates_in CCO:I0006212 ! wrn-terf2-3 colocalization relationship: participates_in CCO:I0006534 ! wrn-terf2-1 physical interaction relationship: participates_in CCO:I0006535 ! wrn-p53-1 direct interaction relationship: participates_in CCO:I0006536 ! wrn-p53-2 direct interaction relationship: participates_in CCO:I0006734 ! wrn-rpa1-2 physical interaction relationship: participates_in CCO:I0006735 ! wrn-rpa1-3 physical interaction relationship: participates_in CCO:I0006736 ! wrn-rpa1-4 physical interaction relationship: participates_in CCO:I0006875 ! wrn-terf2-4 direct interaction relationship: participates_in CCO:I0006876 ! wrn-terf2-5 direct interaction relationship: participates_in CCO:I0006877 ! wrn-terf2-6 direct interaction relationship: participates_in CCO:I0006878 ! wrn-terf2-7 direct interaction relationship: participates_in CCO:I0006981 ! wrn-terf2-2 physical interaction relationship: participates_in CCO:I0007127 ! wrn-rad52-6 physical interaction relationship: participates_in CCO:I0007128 ! wrn-rad52-7 physical interaction relationship: participates_in CCO:I0007281 ! wrn-rpa70-1 physical interaction relationship: participates_in CCO:I0007436 ! wrn-rad52-1 physical interaction relationship: participates_in CCO:I0007439 ! wrn-rad52-2 direct interaction relationship: participates_in CCO:I0007440 ! wrn-rad52-3 direct interaction relationship: participates_in CCO:I0007441 ! wrn-rad52-4 direct interaction relationship: participates_in CCO:I0007442 ! wrn-rad52-5 direct interaction relationship: participates_in CCO:I0007573 ! wrn-terf2-8 direct interaction relationship: participates_in CCO:I0007578 ! p53-wrn-1 direct interaction relationship: participates_in CCO:I0007579 ! p53-wrn-2 direct interaction relationship: participates_in CCO:I0007580 ! wrn-rpa1-7 physical interaction relationship: participates_in CCO:I0007759 ! wrn-rpa1-1 physical interaction relationship: participates_in CCO:I0007760 ! wrn-rpa1-5 physical interaction relationship: participates_in CCO:I0007761 ! wrn-rpa1-6 physical interaction relationship: participates_in CCO:I0008566 ! wrn-blm-11 physical interaction relationship: participates_in CCO:I0008570 ! wrn-blm-4 colocalization relationship: participates_in CCO:I0008571 ! wrn-blm-6 direct interaction relationship: participates_in CCO:I0008572 ! wrn-blm-7 direct interaction relationship: participates_in CCO:I0008573 ! wrn-blm-9 direct interaction relationship: participates_in CCO:I0008574 ! wrn-blm-2 colocalization relationship: participates_in CCO:I0008575 ! wrn-blm-5 physical interaction relationship: participates_in CCO:I0008578 ! wrn-blm-3 colocalization relationship: participates_in CCO:I0008584 ! wrn-blm-1 direct interaction relationship: participates_in CCO:I0015954 ! wrn-wrn-1 physical interaction relationship: participates_in CCO:I0015955 ! wrn-g22p1-2 physical interaction relationship: participates_in CCO:I0015956 ! wrn-fen1-1 physical interaction relationship: participates_in CCO:I0015957 ! wrn-fen1-4 physical interaction relationship: participates_in CCO:I0017311 ! parp1-wrn-1 direct interaction relationship: participates_in CCO:I0017312 ! parp1-xrcc5-1 physical interaction relationship: participates_in CCO:I0017759 ! wrn-fen1-2 direct interaction relationship: participates_in CCO:I0017761 ! wrn-fen1-9 physical interaction relationship: participates_in CCO:I0017847 ! wrn-parp1-1 physical interaction relationship: participates_in CCO:I0018203 ! wrn-g22p1-1 physical interaction relationship: participates_in CCO:I0018335 ! xrcc5-g22p1-1 phosphorylation relationship: participates_in CCO:I0018336 ! wrn-g22p1-3 phosphorylation relationship: participates_in CCO:I0018337 ! wrn-fen1-3 direct interaction relationship: participates_in CCO:I0018839 ! wrn-vcp-1 physical interaction relationship: participates_in CCO:I0018842 ! wrn-fen1-8 physical interaction relationship: participates_in CCO:I0018843 ! wrn-fen1-10 physical interaction relationship: participates_in CCO:I0019222 ! wrn-xrcc5-1 physical interaction relationship: participates_in CCO:I0019397 ! wrn-g22p1-4 physical interaction relationship: participates_in CCO:I0019398 ! wrn-fen1-5 direct interaction relationship: participates_in CCO:I0019399 ! wrn-fen1-7 colocalization relationship: participates_in CCO:I0019484 ! wrn-xrcc5-2 physical interaction relationship: participates_in CCO:I0019503 ! wrn-xrcc5-3 physical interaction relationship: participates_in CCO:I0019504 ! wrn-xrcc5-4 physical interaction relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0014697 ! WRN_HUMAN-Phosphoserine1058 relationship: transforms_into CCO:B0014698 ! WRN_HUMAN-Phosphoserine1141 relationship: transforms_into CCO:B0071877 ! WRN_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0071878 ! WRN_HUMAN-Phosphoserine467 [Term] id: CCO:B0005359 name: GBF1_HUMAN def: "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1" [UniProtKB:Q92538] synonym: "BFA-resistant GEF 1" EXACT [UniProtKB:Q92538] xref: EMBL:AAD15903.1 xref: EMBL:AAH07941.2 xref: EMBL:AAH14171.2 xref: EMBL:BAA13379.2 xref: EMBL:CAH71625.1 xref: EMBL:CAH72761.1 xref: EMBL:CAI12515.1 xref: UniProtKB:Q5VXX3 xref: UniProtKB:Q92538 xref: UniProtKB:Q96CK6 xref: UniProtKB:Q96HZ3 xref: UniProtKB:Q9H473 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004687 ! GBF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006034 ! argef1-gbf1-6 colocalization relationship: participates_in CCO:I0017044 ! tnfrsf1b-gbf1 physical interaction relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0011921 ! GBF1_HUMAN-Phosphoserine1773 relationship: transforms_into CCO:B0011922 ! GBF1_HUMAN-Phosphoserine1784 relationship: transforms_into CCO:B0066393 ! GBF1_HUMAN-Phosphothreonine507 relationship: transforms_into CCO:B0066394 ! GBF1_HUMAN-Phosphoserine662 relationship: transforms_into CCO:B0066395 ! GBF1_HUMAN-Phosphoserine1298 relationship: transforms_into CCO:B0066396 ! GBF1_HUMAN-Phosphoserine1318 [Term] id: CCO:B0005360 name: MRGBP_HUMAN def: "MRG-binding protein" [UniProtKB:Q9NV56] xref: EMBL:AAH09889.1 xref: EMBL:AAH14235.1 xref: EMBL:AAH18841.1 xref: EMBL:BAA91902.1 xref: EMBL:CAC12748.1 xref: UniProtKB:Q9NV56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005125 ! MRGBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007780 ! mrgbp-ruvbl1-2 physical interaction relationship: participates_in CCO:I0007781 ! tcfl1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0017346 ! c20orf20-epc1-5 physical interaction relationship: participates_in CCO:I0018295 ! c20orf20-epc1-3 physical interaction relationship: participates_in CCO:I0018476 ! c20orf20-epc1-1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068287 ! MRGBP_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0068288 ! MRGBP_HUMAN-Phosphoserine195 [Term] id: CCO:B0005361 name: VPS72_HUMAN def: "Vacuolar protein sorting-associated protein 72 homolog" [UniProtKB:Q15906] synonym: "Protein YL-1" EXACT [UniProtKB:Q15906] synonym: "Transcription factor-like 1" EXACT [UniProtKB:Q15906] xref: EMBL:AAH03151.1 xref: EMBL:AAV38163.1 xref: EMBL:AAV38164.1 xref: EMBL:BAA07757.1 xref: EMBL:BAD96655.1 xref: EMBL:BAD96659.1 xref: EMBL:CAI16385.1 xref: EMBL:EAW53462.1 xref: UniProtKB:A6NLK9 xref: UniProtKB:Q15906 xref: UniProtKB:Q53GJ2 xref: UniProtKB:Q5U0R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005906 ! VPS72_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006037 ! znf-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0006982 ! tcfcl1-ruvbl1 physical interaction relationship: participates_in CCO:I0006983 ! tcfcl1-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006984 ! tcfcl1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006985 ! tcfcl1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007773 ! znf-ruvbl physical interaction relationship: participates_in CCO:I0007780 ! mrgbp-ruvbl1-2 physical interaction relationship: participates_in CCO:I0007781 ! tcfl1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0007782 ! znf-ruvbl1 physical interaction relationship: participates_in CCO:I0015288 ! ndp52-tcfl1 physical interaction relationship: participates_in CCO:I0015331 ! ewsr1-tcfl1 physical interaction relationship: participates_in CCO:I0015794 ! mdfi-tcfl1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014648 ! VPS72_HUMAN-Phosphothreonine168 [Term] id: CCO:B0005362 name: ZNHI1_HUMAN def: "Zinc finger HIT domain-containing protein 1" [UniProtKB:O43257] synonym: "Cyclin-G1-binding protein 1" EXACT [UniProtKB:O43257] synonym: "p18 Hamlet" EXACT [UniProtKB:O43257] synonym: "Zinc finger protein subfamily 4A member 1" EXACT [UniProtKB:O43257] xref: EMBL:AAB88578.1 xref: EMBL:AAD45833.1 xref: EMBL:AAF03558.1 xref: EMBL:AAH17333.1 xref: UniProtKB:O43257 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005970 ! ZNHIT1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006037 ! znf-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007773 ! znf-ruvbl physical interaction relationship: participates_in CCO:I0007782 ! znf-ruvbl1 physical interaction relationship: participates_in CCO:I0018458 ! csnk2b-znhit1 physical interaction relationship: transforms_into CCO:B0014749 ! ZNHI1_HUMAN-Phosphothreonine103 [Term] id: CCO:B0005363 name: EAF1_HUMAN def: "ELL-associated factor 1" [UniProtKB:Q96JC9] xref: EMBL:AAH41329.1 xref: EMBL:AAK58687.1 xref: UniProtKB:Q8IW10 xref: UniProtKB:Q96JC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004541 ! EAF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007780 ! mrgbp-ruvbl1-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011622 ! EAF1_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0011623 ! EAF1_HUMAN-Phosphoserine165 [Term] id: CCO:B0005364 name: RUVB2_HUMAN def: "RuvB-like 2" [UniProtKB:Q9Y230] synonym: "48 kDa TATA box-binding protein-interacting protein" EXACT [UniProtKB:Q9Y230] synonym: "48 kDa TBP-interacting protein" EXACT [UniProtKB:Q9Y230] synonym: "51 kDa erythrocyte cytosolic protein" EXACT [UniProtKB:Q9Y230] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9Y230] synonym: "ECP-51" EXACT [UniProtKB:Q9Y230] synonym: "INO80 complex subunit J" EXACT [UniProtKB:Q9Y230] synonym: "Repressing pontin 52" EXACT [UniProtKB:Q9Y230] synonym: "Reptin 52" EXACT [UniProtKB:Q9Y230] synonym: "TAP54-beta" EXACT [UniProtKB:Q9Y230] synonym: "TIP49b" EXACT [UniProtKB:Q9Y230] synonym: "TIP60-associated protein 54-beta" EXACT [UniProtKB:Q9Y230] xref: EMBL:AAD34041.1 xref: EMBL:AAD38073.1 xref: EMBL:AAF87087.1 xref: EMBL:AAH00428.1 xref: EMBL:AAH04531.1 xref: EMBL:AAH08355.1 xref: EMBL:BAA76708.1 xref: EMBL:BAC11048.1 xref: EMBL:CAB46270.1 xref: EMBL:CAB66677.1 xref: EMBL:CAG38538.1 xref: UniProtKB:Q6FIB9 xref: UniProtKB:Q6PK27 xref: UniProtKB:Q9Y230 xref: UniProtKB:Q9Y361 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005549 ! RUVBL2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0001626 ! NuA4 histone acetyltransferase complex relationship: participates_in CCO:I0006019 ! htatip-trrap-1 physical interaction relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006037 ! znf-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0006510 ! ruvbl1-ruvbl2-1 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007773 ! znf-ruvbl physical interaction relationship: participates_in CCO:I0007774 ! znhit4-ruvbl-1 physical interaction relationship: participates_in CCO:I0007775 ! actr8-ruvbl physical interaction relationship: participates_in CCO:I0007777 ! mcrs1-ruvbl physical interaction relationship: participates_in CCO:I0007778 ! fj90652-ruvbl-1 physical interaction relationship: participates_in CCO:I0007779 ! flj20309-ruvbl-2 physical interaction relationship: participates_in CCO:I0007780 ! mrgbp-ruvbl1-2 physical interaction relationship: participates_in CCO:I0007781 ! tcfl1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0007782 ! znf-ruvbl1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015545 ! dpcd-ruvbl2 physical interaction relationship: participates_in CCO:I0016424 ! nfkbie-ruvbl2 physical interaction relationship: participates_in CCO:I0016601 ! map3k1-ruvbl2 physical interaction relationship: participates_in CCO:I0016680 ! map3k3-ruvbl2 physical interaction relationship: participates_in CCO:I0016841 ! map3k14-ruvbl2 physical interaction relationship: participates_in CCO:I0016940 ! q9nyj8-ruvbl2 physical interaction relationship: participates_in CCO:I0016963 ! tbk1-ruvbl2 physical interaction relationship: participates_in CCO:I0017118 ! traf2-ruvbl2 physical interaction relationship: participates_in CCO:I0017318 ! pmscl2-ruvbl2 physical interaction relationship: participates_in CCO:I0018775 ! ruvbl2-ruvbl2 physical interaction relationship: participates_in CCO:I0020445 ! ruvbl2-fdft1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013947 ! RUVB2_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0041340 ! RUVB2_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005365 name: DMAP1_HUMAN def: "DNA methyltransferase 1-associated protein 1" [UniProtKB:Q9NPF5] synonym: "DNMAP1" EXACT [UniProtKB:Q9NPF5] synonym: "DNMT1-associated protein 1" EXACT [UniProtKB:Q9NPF5] xref: EMBL:AAF87079.1 xref: EMBL:AAH02855.1 xref: EMBL:AAH08053.1 xref: EMBL:BAA92663.1 xref: EMBL:BAB13854.1 xref: EMBL:CAB66592.1 xref: EMBL:CAB69910.1 xref: EMBL:CAD97886.1 xref: EMBL:CAI23197.1 xref: EMBL:CAL38490.1 xref: UniProtKB:Q0JSM4 xref: UniProtKB:Q5TG41 xref: UniProtKB:Q7Z3H7 xref: UniProtKB:Q9H0S8 xref: UniProtKB:Q9NPF5 xref: UniProtKB:Q9P2C2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004483 ! DMAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006037 ! znf-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007773 ! znf-ruvbl physical interaction relationship: participates_in CCO:I0017359 ! dmap1-tsg101 physical interaction relationship: participates_in CCO:I0018295 ! c20orf20-epc1-3 physical interaction relationship: participates_in CCO:I0018476 ! c20orf20-epc1-1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000646 ! DNA methylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0011544 ! DMAP1_HUMAN-Phosphothreonine445 relationship: transforms_into CCO:B0011545 ! DMAP1_HUMAN-Phosphoserine456 [Term] id: CCO:B0005366 name: ACL6A_HUMAN def: "Actin-like protein 6A" [UniProtKB:O96019] synonym: "53 kDa BRG1-associated factor A" EXACT [UniProtKB:O96019] synonym: "Actin-related protein Baf53a" EXACT [UniProtKB:O96019] synonym: "ArpNbeta" EXACT [UniProtKB:O96019] synonym: "INO80 complex subunit K" EXACT [UniProtKB:O96019] xref: EMBL:AAC94991.1 xref: EMBL:AAH00949.1 xref: EMBL:AAH01391.1 xref: EMBL:AAH36371.1 xref: EMBL:BAA74577.1 xref: EMBL:BAB87844.1 xref: EMBL:BAB87848.1 xref: EMBL:CAB66543.1 xref: UniProtKB:O96019 xref: UniProtKB:Q8TAE5 xref: UniProtKB:Q9BVS8 xref: UniProtKB:Q9H0W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004017 ! ACTL6A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006019 ! htatip-trrap-1 physical interaction relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006037 ! znf-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0007773 ! znf-ruvbl physical interaction relationship: participates_in CCO:I0007774 ! znhit4-ruvbl-1 physical interaction relationship: participates_in CCO:I0007775 ! actr8-ruvbl physical interaction relationship: participates_in CCO:I0007777 ! mcrs1-ruvbl physical interaction relationship: participates_in CCO:I0007778 ! fj90652-ruvbl-1 physical interaction relationship: participates_in CCO:I0007779 ! flj20309-ruvbl-2 physical interaction relationship: participates_in CCO:I0007780 ! mrgbp-ruvbl1-2 physical interaction relationship: participates_in CCO:I0007781 ! tcfl1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0007782 ! znf-ruvbl1 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0015332 ! actl6a-ewsr1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010433 ! ACL6A_HUMAN-Phosphoserine233 [Term] id: CCO:B0005367 name: ARP6_HUMAN def: "Actin-related protein 6" [UniProtKB:Q9GZN1] synonym: "hArp6" EXACT [UniProtKB:Q9GZN1] synonym: "hARPX" EXACT [UniProtKB:Q9GZN1] xref: EMBL:AAH15107.1 xref: EMBL:AAK14934.1 xref: EMBL:BAB14588.1 xref: EMBL:BAB14640.1 xref: EMBL:BAB20762.1 xref: UniProtKB:Q9BY39 xref: UniProtKB:Q9GZN1 xref: UniProtKB:Q9H8H6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004100 ! ACTR6_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006038 ! tclf1-ruvbl1-3 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006042 ! tclf1-ruvbl1-7 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction [Term] id: CCO:B0005368 name: ING3_HUMAN def: "Inhibitor of growth protein 3" [UniProtKB:Q9NXR8] synonym: "p47ING3 protein" EXACT [UniProtKB:Q9NXR8] xref: EMBL:AAF28979.1 xref: EMBL:AAG12172.1 xref: EMBL:AAG23285.1 xref: EMBL:AAH09776.1 xref: EMBL:AAH09777.1 xref: EMBL:AAH10851.1 xref: EMBL:AAH62634.1 xref: EMBL:AAH73865.1 xref: EMBL:AAQ93373.1 xref: EMBL:AAQ93374.1 xref: EMBL:BAA90942.1 xref: EMBL:CAC48260.2 xref: UniProtKB:O60394 xref: UniProtKB:Q6GMT3 xref: UniProtKB:Q7Z762 xref: UniProtKB:Q969G0 xref: UniProtKB:Q96DT4 xref: UniProtKB:Q9HC99 xref: UniProtKB:Q9NXR8 xref: UniProtKB:Q9P081 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004893 ! ING3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0006041 ! tclf1-ruvbl1-6 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005369 name: EPC1_HUMAN def: "Enhancer of polycomb homolog 1" [UniProtKB:Q9H2F5] xref: EMBL:AAG41402.1 xref: EMBL:AAH36529.1 xref: EMBL:AAK60501.1 xref: EMBL:BAB14888.1 xref: EMBL:BAC03857.1 xref: EMBL:CAH70453.1 xref: EMBL:CAH70454.1 xref: EMBL:CAH70455.1 xref: EMBL:CAH70821.1 xref: EMBL:CAH70822.1 xref: EMBL:CAH70823.1 xref: UniProtKB:Q5VW54 xref: UniProtKB:Q5VW56 xref: UniProtKB:Q5VW58 xref: UniProtKB:Q8NAQ4 xref: UniProtKB:Q8NE21 xref: UniProtKB:Q96LF4 xref: UniProtKB:Q96RR6 xref: UniProtKB:Q9H2F5 xref: UniProtKB:Q9H7T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004571 ! EPC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002562 ! negative regulation of gene expression, epigenetic relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0011719 ! EPC1_HUMAN-Phosphoserine357 [Term] id: CCO:B0005370 name: MO4L2_HUMAN def: "Mortality factor 4-like protein 2" [UniProtKB:Q15014] synonym: "MORF-related gene X protein" EXACT [UniProtKB:Q15014] synonym: "MSL3-2 protein" EXACT [UniProtKB:Q15014] synonym: "Transcription factor-like protein MRGX" EXACT [UniProtKB:Q15014] xref: EMBL:AAD29873.1 xref: EMBL:AAF80855.1 xref: EMBL:AAH56899.1 xref: EMBL:AAH93013.1 xref: EMBL:BAA03553.1 xref: EMBL:BAC22659.1 xref: EMBL:CAB55701.1 xref: UniProtKB:Q15014 xref: UniProtKB:Q567V0 xref: UniProtKB:Q8J026 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005109 ! MORF4L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006561 ! morf4l2-rb1-1 physical interaction relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:I0016212 ! morf4l2-cdr2-3 direct interaction relationship: participates_in CCO:I0017346 ! c20orf20-epc1-5 physical interaction relationship: participates_in CCO:I0017413 ! morf4l2-mrfap1-1 physical interaction relationship: participates_in CCO:I0018269 ! cdr2-morf4l2-1 direct interaction relationship: participates_in CCO:I0018406 ! morf4l2-cdr2-1 physical interaction relationship: participates_in CCO:I0018407 ! morf4l2-cdr2-2 physical interaction relationship: participates_in CCO:I0018701 ! morf4l2-hdac1-1 physical interaction relationship: participates_in CCO:I0018760 ! cdr2-morf4l2-2 physical interaction relationship: participates_in CCO:I0019479 ! cdr2-morf4l2 direct interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068248 ! MO4L2_HUMAN-Phosphoserine71 [Term] id: CCO:B0005371 name: EPC2_HUMAN def: "Enhancer of polycomb homolog 2" [UniProtKB:Q52LR7] synonym: "EPC-like" EXACT [UniProtKB:Q52LR7] xref: EMBL:AAH93818.1 xref: EMBL:AAH93820.1 xref: EMBL:AAK60500.1 xref: EMBL:BAA91688.1 xref: EMBL:BAA92032.1 xref: EMBL:CAB55993.1 xref: UniProtKB:Q52LR7 xref: UniProtKB:Q7L9J1 xref: UniProtKB:Q96RR7 xref: UniProtKB:Q9NUT8 xref: UniProtKB:Q9NVR1 xref: UniProtKB:Q9UFM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004572 ! EPC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006035 ! mrgbp-ruvbl1-1 physical interaction relationship: participates_in CCO:I0006036 ! tclf1-ruvbl1-2 physical interaction relationship: participates_in CCO:I0006039 ! tclf1-ruvbl1-4 physical interaction relationship: participates_in CCO:I0006040 ! tclf1-ruvbl1-5 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007772 ! mrgbp-ruvbl1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005372 name: ADAM9_HUMAN def: "ADAM 9 precursor" [UniProtKB:Q13443] synonym: "A disintegrin and metalloproteinase domain 9" EXACT [UniProtKB:Q13443] synonym: "Cellular disintegrin-related protein" EXACT [UniProtKB:Q13443] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q13443] synonym: "Meltrin-gamma" EXACT [UniProtKB:Q13443] synonym: "Metalloprotease/disintegrin/cysteine-rich protein 9" EXACT [UniProtKB:Q13443] synonym: "Myeloma cell metalloproteinase" EXACT [UniProtKB:Q13443] xref: EMBL:AAC50403.1 xref: EMBL:AAM49575.1 xref: EMBL:BAA03499.2 xref: UniProtKB:Q10718 xref: UniProtKB:Q13443 xref: UniProtKB:Q8NFM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004029 ! ADAM9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006043 ! adam9-mad2l2-3 physical interaction relationship: participates_in CCO:I0006628 ! adam9-mad2l2-2 physical interaction relationship: participates_in CCO:I0007286 ! adam9-mad2l2-1 physical interaction relationship: participates_in CCO:I0017896 ! adam9-sh3gl2-3 physical interaction relationship: participates_in CCO:I0018339 ! adam9-pacsin3-1 physical interaction relationship: participates_in CCO:I0018340 ! adam9-sh3gl2-1 physical interaction relationship: participates_in CCO:I0018525 ! adam9-pacsin3-3 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0010458 ! ADAM9_HUMAN-Phosphoserine758 relationship: transforms_into CCO:B0010459 ! ADAM9_HUMAN-Phosphothreonine761 relationship: transforms_into CCO:B0065402 ! ADAM9_HUMAN-Phosphotyrosine815 [Term] id: CCO:B0005373 name: TPD52_HUMAN def: "Tumor protein D52" [UniProtKB:P55327] synonym: "Protein N8" EXACT [UniProtKB:P55327] xref: EMBL:AAB36475.1 xref: EMBL:AAC50183.1 xref: EMBL:AAH18117.1 xref: EMBL:AAO22156.1 xref: EMBL:AAV38251.1 xref: EMBL:BAG35954.1 xref: EMBL:CAE45908.1 xref: EMBL:CAG46831.1 xref: EMBL:CAG46861.1 xref: EMBL:EAW87074.1 xref: UniProtKB:P55327 xref: UniProtKB:Q13056 xref: UniProtKB:Q6FGP3 xref: UniProtKB:Q6FGS3 xref: UniProtKB:Q86YZ2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005816 ! TPD52_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006044 ! hd52-hd53-1 physical interaction relationship: participates_in CCO:I0006045 ! hd53-hd52-1 physical interaction relationship: participates_in CCO:I0007586 ! hd52-hd53-2 physical interaction relationship: transforms_into CCO:B0071472 ! TPD52_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0071473 ! TPD52_HUMAN-Phosphothreonine173 relationship: transforms_into CCO:B0071474 ! TPD52_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0071475 ! TPD52_HUMAN-Phosphoserine223 [Term] id: CCO:B0005374 name: APLP2_HUMAN def: "Amyloid-like protein 2 precursor" [UniProtKB:Q06481] synonym: "Amyloid protein homolog" EXACT [UniProtKB:Q06481] synonym: "APPH" EXACT [UniProtKB:Q06481] synonym: "CDEBP" EXACT [UniProtKB:Q06481] synonym: "CDEI box-binding protein" EXACT [UniProtKB:Q06481] xref: EMBL:AAA35526.1 xref: EMBL:AAA35601.1 xref: EMBL:AAA36032.1 xref: EMBL:AAA36130.1 xref: EMBL:AAC41701.1 xref: EMBL:AAC60589.1 xref: EMBL:AAD47291.1 xref: EMBL:AAH00373.1 xref: EMBL:AAH04371.1 xref: EMBL:CAA80295.1 xref: UniProtKB:Q06481 xref: UniProtKB:Q13861 xref: UniProtKB:Q14594 xref: UniProtKB:Q14662 xref: UniProtKB:Q71U10 xref: UniProtKB:Q7M4L3 xref: UniProtKB:Q9BT36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004083 ! APLP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006047 ! aplp2-apbb2-1 physical interaction relationship: participates_in CCO:I0007060 ! apbb1-aplp2-1 physical interaction relationship: participates_in CCO:I0018134 ! apbb3-aplp2 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0065692 ! APLP2_HUMAN-Phosphotyrosine750 relationship: transforms_into CCO:B0065693 ! APLP2_HUMAN-Phosphotyrosine755 [Term] id: CCO:B0005375 name: STK36_HUMAN def: "Serine/threonine-protein kinase 36" [UniProtKB:Q9NRP7] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9NRP7] synonym: "Fused homolog" EXACT [UniProtKB:Q9NRP7] xref: EMBL:AAF97028.1 xref: EMBL:AAH26158.1 xref: EMBL:BAA86592.1 xref: EMBL:BAB14184.1 xref: EMBL:CAB63754.1 xref: UniProtKB:Q8TC32 xref: UniProtKB:Q9H9N9 xref: UniProtKB:Q9NRP7 xref: UniProtKB:Q9UF35 xref: UniProtKB:Q9ULE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005693 ! STK36_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006048 ! stk36-sufu-1 physical interaction relationship: participates_in CCO:I0006049 ! stk36-sufu-2 physical interaction relationship: participates_in CCO:I0015964 ! stk36-gli1-1 physical interaction relationship: participates_in CCO:I0015965 ! stk36-gli3-1 physical interaction relationship: participates_in CCO:P0003021 ! regulation of transcription factor activity [Term] id: CCO:B0005376 name: NP1L1_HUMAN def: "Nucleosome assembly protein 1-like 1" [UniProtKB:P55209] synonym: "hNRP" EXACT [UniProtKB:P55209] synonym: "NAP-1-related protein" EXACT [UniProtKB:P55209] xref: EMBL:AAC37544.1 xref: EMBL:AAH02387.1 xref: EMBL:AAP35669.1 xref: EMBL:CAB82405.1 xref: UniProtKB:P55209 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005210 ! NAP1L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006050 ! ep300-nap1l1-3 direct interaction relationship: participates_in CCO:I0007787 ! ep300-nap1l1-4 physical interaction relationship: participates_in CCO:I0007788 ! ep300-nap1l1-5 physical interaction relationship: participates_in CCO:I0008655 ! nap1l1-fsd1 physical interaction relationship: participates_in CCO:I0015969 ! crebbp-nap1l1-2 direct interaction relationship: participates_in CCO:I0016578 ! tank-nap1l1 physical interaction relationship: participates_in CCO:I0017011 ! tnfrsf1a-nap1l1 physical interaction relationship: participates_in CCO:I0017073 ! tradd-nap1l1 physical interaction relationship: participates_in CCO:I0017098 ! traf1-nap1l1 physical interaction relationship: participates_in CCO:I0017124 ! traf2-nap1l1 physical interaction relationship: participates_in CCO:I0017739 ! crebbp-nap1l1 physical interaction relationship: participates_in CCO:I0019290 ! crebbp-nap1l1-1 physical interaction relationship: participates_in CCO:I0020081 ! nap1l1-dlst physical interaction relationship: participates_in CCO:I0020380 ! nap1l1-nap1l1 physical interaction relationship: participates_in CCO:I0020606 ! nap1l1-hba1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0013244 ! NP1L1_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0013245 ! NP1L1_HUMAN-Phosphothreonine62 relationship: transforms_into CCO:B0068808 ! NP1L1_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0068809 ! NP1L1_HUMAN-Phosphoserine143 [Term] id: CCO:B0005377 name: AP2C_HUMAN def: "Transcription factor AP-2 gamma" [UniProtKB:Q92754] synonym: "Activating enhancer-binding protein 2 gamma" EXACT [UniProtKB:Q92754] synonym: "AP2-gamma" EXACT [UniProtKB:Q92754] synonym: "Transcription factor ERF-1" EXACT [UniProtKB:Q92754] xref: EMBL:AAC51305.1 xref: EMBL:AAH35664.2 xref: EMBL:AAH51829.2 xref: EMBL:BAC11805.1 xref: EMBL:CAA64989.1 xref: EMBL:CAC10334.1 xref: EMBL:CAC86997.1 xref: UniProtKB:O00685 xref: UniProtKB:O00730 xref: UniProtKB:Q86V30 xref: UniProtKB:Q8IVB6 xref: UniProtKB:Q92754 xref: UniProtKB:Q9P1X2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004075 ! TFAP2C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006056 ! ap2g-ubc9-1 physical interaction relationship: participates_in CCO:I0006893 ! cited2-tfap2c-1 physical interaction relationship: participates_in CCO:I0007793 ! tfap2c-cited2-1 physical interaction relationship: participates_in CCO:I0007920 ! ap2g-ubc9-2 physical interaction relationship: participates_in CCO:I0007923 ! ubc9-ap2g-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0010566 ! AP2C_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0065664 ! AP2C_HUMAN-Phosphoserine434 [Term] id: CCO:B0005378 name: S100B_HUMAN def: "Protein S100-B" [UniProtKB:P04271] synonym: "S-100 protein beta chain" EXACT [UniProtKB:P04271] synonym: "S-100 protein subunit beta" EXACT [UniProtKB:P04271] synonym: "S100 calcium-binding protein B" EXACT [UniProtKB:P04271] xref: EMBL:AAA60367.1 xref: EMBL:AAH01766.1 xref: EMBL:CAG46920.1 xref: UniProtKB:P04271 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005551 ! S100B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006057 ! s100b-s100a6-1 physical interaction relationship: participates_in CCO:I0006219 ! s100b-s100a6-3 physical interaction relationship: participates_in CCO:I0006895 ! s100a6-s100b-1 physical interaction relationship: participates_in CCO:I0006896 ! s100b-s100a6-2 physical interaction relationship: participates_in CCO:I0007148 ! s100b-s100a11-s100a6 colocalization relationship: participates_in CCO:I0015841 ! s100a1-s100b physical interaction relationship: participates_in CCO:I0015972 ! s100b-s100a11-1 physical interaction relationship: participates_in CCO:I0015973 ! s100a1-s100b-1 physical interaction relationship: participates_in CCO:I0015974 ! s100b-s100b-1 physical interaction relationship: participates_in CCO:I0016192 ! s100b-s100b-4 physical interaction relationship: participates_in CCO:I0016193 ! s100b-s100a11-3 physical interaction relationship: participates_in CCO:I0016194 ! s100b-s100a1-1 physical interaction relationship: participates_in CCO:I0017917 ! s100b-s100b-2 physical interaction relationship: participates_in CCO:I0017918 ! s100b-s100b-3 physical interaction relationship: participates_in CCO:I0017920 ! s100b-s100a11-2 physical interaction relationship: participates_in CCO:I0017921 ! s100a11-s100b-1 physical interaction relationship: participates_in CCO:I0017923 ! s100a1-s100b-2 physical interaction relationship: participates_in CCO:I0017925 ! s100b-s100a1-2 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0013948 ! S100B_HUMAN-Blocked amino end (Ser)2 [Term] id: CCO:B0005379 name: STAT3_HUMAN def: "Signal transducer and activator of transcription 3" [UniProtKB:P40763] synonym: "Acute-phase response factor" EXACT [UniProtKB:P40763] xref: EMBL:AAA58374.1 xref: EMBL:AAB84254.1 xref: EMBL:AAH00627.1 xref: EMBL:AAH14482.1 xref: EMBL:AAS66986.1 xref: EMBL:CAA10032.1 xref: UniProtKB:O14916 xref: UniProtKB:P40763 xref: UniProtKB:Q9BW54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005687 ! STAT3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006060 ! daxx-stat3-1 physical interaction relationship: participates_in CCO:I0006061 ! daxx-stat3-2 physical interaction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0006666 ! daxx-stat3 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007152 ! daxx-stat3-3 colocalization relationship: participates_in CCO:I0007346 ! khdrbs1-stat3-1 physical interaction relationship: participates_in CCO:I0007347 ! khdrbs1-stat3-2 physical interaction relationship: participates_in CCO:I0017373 ! tak1-stat3-4 physical interaction relationship: participates_in CCO:I0017634 ! stat3-npm_alk physical interaction relationship: participates_in CCO:I0018057 ! tak1-stat3-2 physical interaction relationship: participates_in CCO:I0018058 ! tak1-stat3-3 physical interaction relationship: participates_in CCO:I0018059 ! tak1-stat3-5 physical interaction relationship: participates_in CCO:I0018060 ! tak1-stat3-6 physical interaction relationship: participates_in CCO:I0018130 ! nmi-stat3-1 physical interaction relationship: participates_in CCO:I0018345 ! pim1-bmx-7 physical interaction relationship: participates_in CCO:I0018675 ! pim1-bmx-6 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014245 ! STAT3_HUMAN-Phosphoserine691 relationship: transforms_into CCO:B0014246 ! STAT3_HUMAN-Phosphotyrosine705 relationship: transforms_into CCO:B0014247 ! STAT3_HUMAN-Phosphoserine727 relationship: transforms_into CCO:B0070966 ! STAT3_HUMAN-Phosphothreonine714 [Term] id: CCO:B0005380 name: AIP_HUMAN def: "AH receptor-interacting protein" [UniProtKB:O00170] synonym: "AIP" EXACT [UniProtKB:O00170] synonym: "Aryl-hydrocarbon receptor-interacting protein" EXACT [UniProtKB:O00170] synonym: "HBV X-associated protein 2" EXACT [UniProtKB:O00170] synonym: "Immunophilin homolog ARA9" EXACT [UniProtKB:O00170] synonym: "XAP-2" EXACT [UniProtKB:O00170] xref: EMBL:AAB39923.1 xref: EMBL:AAB59004.1 xref: EMBL:AAI04798.1 xref: EMBL:AAI04828.1 xref: EMBL:CAJ85657.1 xref: UniProtKB:O00170 xref: UniProtKB:Q2M3Q2 xref: UniProtKB:Q99606 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004040 ! AIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006062 ! ahr-aip colocalization relationship: participates_in CCO:I0006063 ! ahr-aip-1 colocalization relationship: participates_in CCO:I0007813 ! ahr-aip-2 physical interaction relationship: transforms_into CCO:B0010481 ! AIP_HUMAN-Phosphotyrosine248 [Term] id: CCO:B0005381 name: FGFR2_HUMAN def: "Fibroblast growth factor receptor 2 precursor" [UniProtKB:P21802] synonym: "CD332 antigen" EXACT [UniProtKB:P21802] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P21802] synonym: "FGFR-2" EXACT [UniProtKB:P21802] synonym: "Keratinocyte growth factor receptor 2" EXACT [UniProtKB:P21802] xref: EMBL:AAA36147.1 xref: EMBL:AAA36152.1 xref: EMBL:AAA52449.1 xref: EMBL:AAA59470.1 xref: EMBL:AAA59471.1 xref: EMBL:AAA59472.1 xref: EMBL:AAA61188.1 xref: EMBL:AAA68514.1 xref: EMBL:AAC41933.1 xref: EMBL:AAC41934.1 xref: EMBL:AAC41935.1 xref: EMBL:AAC41936.1 xref: EMBL:AAC41937.1 xref: EMBL:AAC41938.1 xref: EMBL:AAD14392.1 xref: EMBL:AAD31560.1 xref: EMBL:AAD31561.1 xref: EMBL:AAD31562.1 xref: EMBL:AAD31565.1 xref: EMBL:AAD31567.1 xref: EMBL:AAF43273.1 xref: EMBL:AAF43274.1 xref: EMBL:AAH39243.2 xref: EMBL:AAK94205.1 xref: EMBL:AAK94206.1 xref: EMBL:AAK94207.1 xref: EMBL:AAK94208.1 xref: EMBL:AAK94209.1 xref: EMBL:AAM74056.1 xref: EMBL:BAA89296.1 xref: EMBL:BAA89297.1 xref: EMBL:BAA89298.1 xref: EMBL:BAA89299.1 xref: EMBL:BAA89300.1 xref: EMBL:BAA89301.1 xref: EMBL:CAA37014.1 xref: EMBL:CAA39654.1 xref: EMBL:CAA76643.1 xref: EMBL:CAA96492.1 xref: UniProtKB:P18443 xref: UniProtKB:P21802 xref: UniProtKB:Q01742 xref: UniProtKB:Q12922 xref: UniProtKB:Q14300 xref: UniProtKB:Q14301 xref: UniProtKB:Q14302 xref: UniProtKB:Q14303 xref: UniProtKB:Q14304 xref: UniProtKB:Q14305 xref: UniProtKB:Q14672 xref: UniProtKB:Q14718 xref: UniProtKB:Q14719 xref: UniProtKB:Q86YI4 xref: UniProtKB:Q96KL9 xref: UniProtKB:Q96KM0 xref: UniProtKB:Q96KM1 xref: UniProtKB:Q96KM2 xref: UniProtKB:Q9NZU2 xref: UniProtKB:Q9NZU3 xref: UniProtKB:Q9UD01 xref: UniProtKB:Q9UD02 xref: UniProtKB:Q9UIH3 xref: UniProtKB:Q9UIH4 xref: UniProtKB:Q9UIH5 xref: UniProtKB:Q9UIH6 xref: UniProtKB:Q9UIH7 xref: UniProtKB:Q9UIH8 xref: UniProtKB:Q9UM87 xref: UniProtKB:Q9UMC6 xref: UniProtKB:Q9UNS7 xref: UniProtKB:Q9UQH7 xref: UniProtKB:Q9UQH8 xref: UniProtKB:Q9UQH9 xref: UniProtKB:Q9UQI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004643 ! FGFR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006067 ! fgf1-fgfr2-1 direct interaction relationship: participates_in CCO:I0006233 ! fgf2-fgfr2-1 direct interaction relationship: participates_in CCO:I0006234 ! fgf2-fgfr2-2 direct interaction relationship: participates_in CCO:I0007469 ! fgf1-fgfr2-2 direct interaction relationship: participates_in CCO:I0007827 ! fgf10-fgfr2-1 direct interaction relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: transforms_into CCO:B0011879 ! FGFR2_HUMAN-Phosphotyrosine657 [Term] id: CCO:B0005382 name: NFYB_HUMAN def: "Nuclear transcription factor Y subunit beta" [UniProtKB:P25208] synonym: "CAAT-box DNA-binding protein subunit B" EXACT [UniProtKB:P25208] synonym: "NF-YB" EXACT [UniProtKB:P25208] synonym: "Nuclear transcription factor Y subunit B" EXACT [UniProtKB:P25208] xref: EMBL:AAA59930.1 xref: EMBL:AAH05316.1 xref: EMBL:AAH05317.1 xref: EMBL:AAH07035.1 xref: EMBL:CAA42230.1 xref: UniProtKB:P25208 xref: UniProtKB:Q96IY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005190 ! NFYB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000816 ! CCAAT-binding factor complex relationship: participates_in CCO:I0006068 ! nfyb-nfyc-1 direct interaction relationship: participates_in CCO:I0006562 ! tp53-nfya-2 physical interaction relationship: participates_in CCO:I0006847 ! cbfa-cbfb-1 physical interaction relationship: participates_in CCO:I0006920 ! tp53-nfya-6 physical interaction relationship: participates_in CCO:I0006921 ! nfya-tp53-2 physical interaction relationship: participates_in CCO:I0006952 ! cbfa-cbfb physical interaction relationship: participates_in CCO:I0007707 ! tp53-nfya physical interaction relationship: participates_in CCO:I0007824 ! tp53-nfya-1 physical interaction relationship: participates_in CCO:I0015019 ! drap1-nfyb physical interaction relationship: participates_in CCO:I0017958 ! nfya-tp53-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005383 name: SOS1_HUMAN def: "Son of sevenless homolog 1" [UniProtKB:Q07889] synonym: "SOS-1" EXACT [UniProtKB:Q07889] xref: EMBL:AAA35913.1 xref: UniProtKB:Q07889 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005649 ! SOS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006069 ! hras-sos1-6 direct interaction relationship: participates_in CCO:I0006450 ! hras-sos1-1 direct interaction relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0006843 ! sos1-cd2ap-1 physical interaction relationship: participates_in CCO:I0007937 ! hras-sos1-2 direct interaction relationship: participates_in CCO:I0007938 ! hras-sos1-3 direct interaction relationship: participates_in CCO:I0007939 ! hras-sos1-4 direct interaction relationship: participates_in CCO:I0007940 ! hras-sos1-5 direct interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017395 ! nck-sos1-1 physical interaction relationship: participates_in CCO:I0017452 ! sh3bp5-sos1 physical interaction relationship: participates_in CCO:I0017833 ! sos1-grb2-1 physical interaction relationship: participates_in CCO:I0017834 ! sos1-pacsin3-1 physical interaction relationship: participates_in CCO:I0017835 ! sos1-snx9-1 physical interaction relationship: participates_in CCO:I0017836 ! sos1-snag1-1 physical interaction relationship: participates_in CCO:I0018427 ! hck-sos1-1 physical interaction relationship: participates_in CCO:I0019219 ! sos1-grb2-2 physical interaction relationship: participates_in CCO:I0019220 ! sos1-pacsin3-2 physical interaction relationship: participates_in CCO:I0019221 ! sos1-snx9-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0014152 ! SOS1_HUMAN-Phosphoserine1043 relationship: transforms_into CCO:B0014153 ! SOS1_HUMAN-Phosphoserine1078 relationship: transforms_into CCO:B0014154 ! SOS1_HUMAN-Phosphoserine1082 relationship: transforms_into CCO:B0014155 ! SOS1_HUMAN-Phosphoserine1210 relationship: transforms_into CCO:B0070746 ! SOS1_HUMAN-Phosphoserine1134 relationship: transforms_into CCO:B0070747 ! SOS1_HUMAN-Phosphoserine1137 [Term] id: CCO:B0005384 name: NFYA_HUMAN def: "Nuclear transcription factor Y subunit alpha" [UniProtKB:P23511] synonym: "CAAT-box DNA-binding protein subunit A" EXACT [UniProtKB:P23511] synonym: "NF-YA" EXACT [UniProtKB:P23511] synonym: "Nuclear transcription factor Y subunit A" EXACT [UniProtKB:P23511] xref: EMBL:AAA35950.1 xref: EMBL:AAH39244.1 xref: EMBL:CAA42231.1 xref: EMBL:CAB44743.1 xref: EMBL:CAI20286.1 xref: UniProtKB:P23511 xref: UniProtKB:Q8IXU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005189 ! NFYA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000816 ! CCAAT-binding factor complex relationship: participates_in CCO:I0006070 ! tp53-nfya-8 colocalization relationship: participates_in CCO:I0006562 ! tp53-nfya-2 physical interaction relationship: participates_in CCO:I0006564 ! tp53-nfya-3 physical interaction relationship: participates_in CCO:I0006565 ! tp53-nfya-4 physical interaction relationship: participates_in CCO:I0006567 ! tp53-nfya-7 physical interaction relationship: participates_in CCO:I0006847 ! cbfa-cbfb-1 physical interaction relationship: participates_in CCO:I0006917 ! nfya-tp53 physical interaction relationship: participates_in CCO:I0006918 ! nfya-tp53-1 physical interaction relationship: participates_in CCO:I0006919 ! tp53-nfya-5 physical interaction relationship: participates_in CCO:I0006920 ! tp53-nfya-6 physical interaction relationship: participates_in CCO:I0006921 ! nfya-tp53-2 physical interaction relationship: participates_in CCO:I0006952 ! cbfa-cbfb physical interaction relationship: participates_in CCO:I0007707 ! tp53-nfya physical interaction relationship: participates_in CCO:I0007824 ! tp53-nfya-1 physical interaction relationship: participates_in CCO:I0017958 ! nfya-tp53-3 physical interaction relationship: participates_in CCO:I0017982 ! cbfb-p32-1 physical interaction relationship: participates_in CCO:I0017983 ! cbfb-p32-2 physical interaction relationship: participates_in CCO:I0018589 ! cbfb-p32-3 colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005385 name: RIN1_HUMAN def: "Ras and Rab interactor 1" [UniProtKB:Q13671] synonym: "Ras inhibitor JC99" EXACT [UniProtKB:Q13671] synonym: "Ras interaction/interference protein 1" EXACT [UniProtKB:Q13671] xref: EMBL:AAB67270.1 xref: EMBL:AAH14417.1 xref: UniProtKB:O15010 xref: UniProtKB:Q00427 xref: UniProtKB:Q13671 xref: UniProtKB:Q96CC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005490 ! RIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006071 ! abl1-rin1-3 physical interaction relationship: participates_in CCO:I0006922 ! abl1-rin1-1 physical interaction relationship: participates_in CCO:I0006923 ! abl1-rin1-2 physical interaction relationship: participates_in CCO:I0006924 ! abl2-rin1-5 physical interaction relationship: participates_in CCO:I0007170 ! abl2-rin1-4 physical interaction relationship: participates_in CCO:I0007171 ! abl1-rin1-4 phosphorylation relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0007472 ! rin1-hras-3 physical interaction relationship: participates_in CCO:I0007831 ! rin1-hras-1 physical interaction relationship: participates_in CCO:I0007832 ! rin1-hras-2 physical interaction relationship: participates_in CCO:I0007833 ! rin1-hras-4 physical interaction relationship: participates_in CCO:I0017959 ! abl2-rin1-2 physical interaction relationship: participates_in CCO:I0018258 ! abl2-rin1-1 physical interaction relationship: participates_in CCO:I0018259 ! abl2-rin1-3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0013870 ! RIN1_HUMAN-Phosphotyrosine36 relationship: transforms_into CCO:B0013871 ! RIN1_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0013872 ! RIN1_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0013873 ! RIN1_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0013874 ! RIN1_HUMAN-Phosphoserine601 relationship: transforms_into CCO:B0048380 ! RIN1_HUMAN-Phosphotyrosine632 relationship: transforms_into CCO:B0070049 ! RIN1_HUMAN-Phosphoserine210 relationship: transforms_into CCO:B0070050 ! RIN1_HUMAN-Phosphothreonine251 relationship: transforms_into CCO:B0070051 ! RIN1_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0070052 ! RIN1_HUMAN-Phosphoserine609 [Term] id: CCO:B0005386 name: FNBP1_HUMAN def: "Formin-binding protein 1" [UniProtKB:Q96RU3] synonym: "Formin-binding protein 17" EXACT [UniProtKB:Q96RU3] synonym: "hFBP17" EXACT [UniProtKB:Q96RU3] xref: EMBL:AAH62463.1 xref: EMBL:AAI01756.1 xref: EMBL:AAK49824.1 xref: EMBL:BAA25480.1 xref: EMBL:BAA91451.1 xref: EMBL:BAB14638.1 xref: EMBL:CAI12149.1 xref: EMBL:CAI12150.1 xref: EMBL:CAI13910.1 xref: EMBL:CAI13911.1 xref: UniProtKB:O60301 xref: UniProtKB:Q3MIN8 xref: UniProtKB:Q5TC87 xref: UniProtKB:Q5TC88 xref: UniProtKB:Q6P658 xref: UniProtKB:Q7LGG2 xref: UniProtKB:Q96RU3 xref: UniProtKB:Q9H8H8 xref: UniProtKB:Q9NWD1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004651 ! FNBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006072 ! fnbp1-dnm2-2 physical interaction relationship: participates_in CCO:I0007506 ! fnbp1-dnm2-1 colocalization relationship: participates_in CCO:I0018260 ! fnbp1-tnks-1 physical interaction relationship: participates_in CCO:I0018261 ! fnbp1-tnks-4 colocalization relationship: participates_in CCO:I0018756 ! fnbp1-tnks-3 physical interaction relationship: participates_in CCO:I0019326 ! fnbp1-tnks-2 physical interaction relationship: transforms_into CCO:B0011885 ! FNBP1_HUMAN-Phosphothreonine294 relationship: transforms_into CCO:B0011886 ! FNBP1_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0011887 ! FNBP1_HUMAN-Phosphoserine299 relationship: transforms_into CCO:B0011888 ! FNBP1_HUMAN-Phosphotyrosine522 relationship: transforms_into CCO:B0031318 ! FNBP1_HUMAN-Phosphoserine497 relationship: transforms_into CCO:B0031319 ! FNBP1_HUMAN-Phosphotyrosine500 relationship: transforms_into CCO:B0066231 ! FNBP1_HUMAN-Phosphoserine349 relationship: transforms_into CCO:B0066232 ! FNBP1_HUMAN-Phosphoserine359 [Term] id: CCO:B0005387 name: TELT_HUMAN def: "Telethonin" [UniProtKB:O15273] synonym: "Titin cap protein" EXACT [UniProtKB:O15273] xref: EMBL:AAH12628.1 xref: EMBL:AAH13330.1 xref: EMBL:CAA04129.1 xref: EMBL:CAA08987.1 xref: EMBL:CAA09479.1 xref: UniProtKB:O15273 xref: UniProtKB:Q96L27 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005759 ! TCAP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000934 ! Z disc relationship: participates_in CCO:I0006073 ! ttn-tcap direct interaction relationship: participates_in CCO:I0017566 ! tcap-atxn1 physical interaction [Term] id: CCO:B0005388 name: ORC6_HUMAN def: "Origin recognition complex subunit 6" [UniProtKB:Q9Y5N6] xref: EMBL:AAD32666.1 xref: EMBL:AAH39032.1 xref: EMBL:AAH63565.1 xref: UniProtKB:Q9Y5N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005237 ! ORC6L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006074 ! mcm2-orc6l direct interaction relationship: participates_in CCO:I0006081 ! orc6l-mcm6 direct interaction relationship: participates_in CCO:I0006090 ! orc6l-cdc7 direct interaction relationship: participates_in CCO:I0006124 ! hscdc6-orc6l direct interaction relationship: participates_in CCO:I0006126 ! orc6l-mcm7 direct interaction relationship: participates_in CCO:I0016016 ! orc6l-orc4l direct interaction relationship: participates_in CCO:I0016018 ! orc6l-mcm4 direct interaction relationship: participates_in CCO:I0016021 ! orc6l-orc3l direct interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0013336 ! ORC6_HUMAN-Phosphothreonine195 relationship: transforms_into CCO:B0013337 ! ORC6_HUMAN-Phosphothreonine229 [Term] id: CCO:B0005389 name: ORC4_HUMAN def: "Origin recognition complex subunit 4" [UniProtKB:O43929] xref: EMBL:AAC01957.1 xref: EMBL:AAC80282.1 xref: EMBL:AAD22110.1 xref: EMBL:AAH14847.1 xref: EMBL:AAS94326.1 xref: UniProtKB:O43929 xref: UniProtKB:Q96C42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005235 ! ORC4L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000280 ! DNA replication origin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006079 ! orc4l-mcm7 direct interaction relationship: participates_in CCO:I0006082 ! mcm10-orc4l direct interaction relationship: participates_in CCO:I0006091 ! orc4l-ccnd1 direct interaction relationship: participates_in CCO:I0006096 ! orc4l-mcm3 direct interaction relationship: participates_in CCO:I0006117 ! orc4l-cdkn2a direct interaction relationship: participates_in CCO:I0016016 ! orc6l-orc4l direct interaction relationship: participates_in CCO:I0016022 ! orc5l-orc4l direct interaction relationship: participates_in CCO:I0016024 ! orc4l-orc3l direct interaction relationship: participates_in CCO:I0016027 ! orc2l-orc4l direct interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation [Term] id: CCO:B0005390 name: ORC5_HUMAN def: "Origin recognition complex subunit 5" [UniProtKB:O43913] xref: EMBL:AAC51933.1 xref: EMBL:AAC63972.1 xref: EMBL:AAC80283.1 xref: EMBL:AAH23652.1 xref: UniProtKB:O43913 xref: UniProtKB:O60590 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005236 ! ORC5L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000280 ! DNA replication origin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006088 ! orc5l-cdc45l direct interaction relationship: participates_in CCO:I0006093 ! mcm3-orc5l direct interaction relationship: participates_in CCO:I0006110 ! mcm2-orc5l direct interaction relationship: participates_in CCO:I0006118 ! orc5l-mcm5 direct interaction relationship: participates_in CCO:I0006122 ! hscdc6-orc5l direct interaction relationship: participates_in CCO:I0006133 ! cdkn2a-orc5l direct interaction relationship: participates_in CCO:I0006138 ! cdc7-orc5l direct interaction relationship: participates_in CCO:I0016017 ! orc3l-orc5l direct interaction relationship: participates_in CCO:I0016019 ! orc1l-orc5l direct interaction relationship: participates_in CCO:I0016022 ! orc5l-orc4l direct interaction relationship: participates_in CCO:I0016025 ! orc2l-orc5l direct interaction relationship: participates_in CCO:I0016026 ! orc5l-orc5l direct interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation [Term] id: CCO:B0005391 name: MCM4_HUMAN def: "DNA replication licensing factor MCM4" [UniProtKB:P33991] synonym: "CDC21 homolog" EXACT [UniProtKB:P33991] synonym: "P1-CDC21" EXACT [UniProtKB:P33991] xref: EMBL:AAB51723.3 xref: EMBL:AAC52018.1 xref: EMBL:AAH31061.1 xref: EMBL:AAS83108.1 xref: EMBL:CAA52801.1 xref: UniProtKB:P33991 xref: UniProtKB:Q8NEH1 xref: UniProtKB:Q99658 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005039 ! MCM4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006099 ! mcm4-hscdc5 direct interaction relationship: participates_in CCO:I0006153 ! mcm4-mcm7 direct interaction relationship: participates_in CCO:I0006157 ! mcm4-ccna1 direct interaction relationship: participates_in CCO:I0007542 ! mcm4-mcm6-1 physical interaction relationship: participates_in CCO:I0007914 ! mcm2-7_human physical interaction relationship: participates_in CCO:I0016018 ! orc6l-mcm4 direct interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012826 ! MCM4_HUMAN-Phosphothreonine19 relationship: transforms_into CCO:B0012827 ! MCM4_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0012828 ! MCM4_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0012829 ! MCM4_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0012830 ! MCM4_HUMAN-Phosphothreonine110 relationship: transforms_into CCO:B0012831 ! MCM4_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0012832 ! MCM4_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0012833 ! MCM4_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0012834 ! MCM4_HUMAN-Phosphoserine145 relationship: transforms_into CCO:B0012835 ! MCM4_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0048317 ! MCM4_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0068064 ! MCM4_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0068065 ! MCM4_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0068066 ! MCM4_HUMAN-Phosphothreonine102 [Term] id: CCO:B0005392 name: ORC3_HUMAN def: "Origin recognition complex subunit 3" [UniProtKB:Q9UBD5] synonym: "Origin recognition complex subunit Latheo" EXACT [UniProtKB:Q9UBD5] xref: EMBL:AAA96313.1 xref: EMBL:AAD18057.1 xref: EMBL:AAD30282.1 xref: EMBL:AAD40220.1 xref: EMBL:AAH35494.1 xref: EMBL:AAH47689.1 xref: EMBL:AAT38109.1 xref: EMBL:BAD96515.1 xref: EMBL:CAB45715.1 xref: EMBL:CAI10900.1 xref: EMBL:CAI21539.1 xref: EMBL:CAM13063.1 xref: EMBL:CAM28255.1 xref: UniProtKB:A2A2T5 xref: UniProtKB:Q13565 xref: UniProtKB:Q53GY6 xref: UniProtKB:Q5T159 xref: UniProtKB:Q6IUY7 xref: UniProtKB:Q86TN5 xref: UniProtKB:Q9UBD5 xref: UniProtKB:Q9UG44 xref: UniProtKB:Q9UNT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005234 ! ORC3L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006107 ! orc3l-ccne2 direct interaction relationship: participates_in CCO:I0006109 ! mcm7-orc3l direct interaction relationship: participates_in CCO:I0006116 ! orc3l-mcm5 direct interaction relationship: participates_in CCO:I0006123 ! orc3l-hscdc6 direct interaction relationship: participates_in CCO:I0006125 ! orc3l-mcm10 direct interaction relationship: participates_in CCO:I0016017 ! orc3l-orc5l direct interaction relationship: participates_in CCO:I0016021 ! orc6l-orc3l direct interaction relationship: participates_in CCO:I0016023 ! orc1l-orc3l direct interaction relationship: participates_in CCO:I0016024 ! orc4l-orc3l direct interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0013334 ! ORC3_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0013335 ! ORC3_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0068991 ! ORC3_HUMAN-Phosphoserine23 [Term] id: CCO:B0005393 name: FEZ1_HUMAN def: "Fasciculation and elongation protein zeta-1" [UniProtKB:Q99689] synonym: "Zygin I" EXACT [UniProtKB:Q99689] synonym: "Zygin-1" EXACT [UniProtKB:Q99689] xref: EMBL:AAB40660.1 xref: EMBL:AAC51282.1 xref: EMBL:AAC51284.1 xref: EMBL:AAH09545.1 xref: EMBL:CAG33098.1 xref: EMBL:CAG46752.1 xref: UniProtKB:O00679 xref: UniProtKB:O00728 xref: UniProtKB:Q6IBI7 xref: UniProtKB:Q99689 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004629 ! FEZ1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005782 ! gamma-tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006164 ! nek1-fez1-2 physical interaction relationship: participates_in CCO:I0006179 ! bard1-fez1 physical interaction relationship: participates_in CCO:I0006192 ! ptn-fez1 physical interaction relationship: participates_in CCO:I0007268 ! nek1-fez1-3 physical interaction relationship: participates_in CCO:I0008389 ! flj22624-fez1 physical interaction relationship: participates_in CCO:I0016073 ! hd-fez1 physical interaction relationship: participates_in CCO:I0016074 ! hd-fez1-1 physical interaction relationship: participates_in CCO:I0018155 ! fez1-hd physical interaction relationship: participates_in CCO:I0020019 ! gtf2f1-fez1 physical interaction relationship: participates_in CCO:I0020098 ! pdcd7-fez1 physical interaction relationship: participates_in CCO:I0020131 ! pth-fez1 physical interaction relationship: participates_in CCO:I0020181 ! tac3-fez1 physical interaction relationship: participates_in CCO:I0020269 ! ccl7-fez1 physical interaction relationship: participates_in CCO:I0020337 ! htatsf1-fez1 physical interaction relationship: transforms_into CCO:B0011875 ! FEZ1_HUMAN-Phosphoserine58 [Term] id: CCO:B0005394 name: FEZ2_HUMAN def: "Fasciculation and elongation protein zeta-2" [UniProtKB:Q9UHY8] synonym: "Zygin II" EXACT [UniProtKB:Q9UHY8] synonym: "Zygin-2" EXACT [UniProtKB:Q9UHY8] xref: EMBL:AAB40661.1 xref: EMBL:AAC51283.1 xref: EMBL:AAF14865.1 xref: EMBL:AAY14650.1 xref: EMBL:BAD06207.1 xref: UniProtKB:Q76LN0 xref: UniProtKB:Q99690 xref: UniProtKB:Q9UHY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004630 ! FEZ2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006165 ! nek1-fez2-1 physical interaction relationship: participates_in CCO:I0007235 ! nek1-fez2-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005395 name: ZHX1_HUMAN def: "Zinc fingers and homeoboxes protein 1" [UniProtKB:Q9UKY1] xref: EMBL:AAD50624.1 xref: EMBL:AAF35183.1 xref: EMBL:AAH40481.1 xref: UniProtKB:Q8IWD8 xref: UniProtKB:Q9UKY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005956 ! ZHX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006167 ! bard1-zhx1 physical interaction relationship: participates_in CCO:I0008136 ! mphosph6-zhx1 physical interaction relationship: participates_in CCO:I0008174 ! terf1-zhx1 physical interaction relationship: participates_in CCO:I0016101 ! taldo1-zhx1 physical interaction relationship: participates_in CCO:I0016104 ! vim-zhx1 physical interaction relationship: participates_in CCO:I0016106 ! fnbp3-zhx1 physical interaction relationship: participates_in CCO:I0016107 ! pias4-zhx1 physical interaction relationship: participates_in CCO:I0016183 ! atxn1-zhx1 physical interaction relationship: participates_in CCO:I0018471 ! bat1-zhx1 physical interaction relationship: participates_in CCO:I0018961 ! atxn1-zhx1-1 physical interaction relationship: participates_in CCO:I0018986 ! atxn1-zhx1-2 physical interaction relationship: participates_in CCO:I0019014 ! atxn1-zhx1-3 physical interaction relationship: participates_in CCO:I0019069 ! atxn1-zhx1-4 physical interaction relationship: participates_in CCO:I0019569 ! bhlhb2-zhx1 physical interaction relationship: participates_in CCO:I0019582 ! dlst-zhx1 physical interaction relationship: participates_in CCO:I0019700 ! csnk2a1-zhx1 physical interaction relationship: participates_in CCO:I0019707 ! dncl1-zhx1 physical interaction relationship: participates_in CCO:I0019742 ! hspe1-zhx1 physical interaction relationship: participates_in CCO:I0019756 ! lama4-zhx1 physical interaction relationship: participates_in CCO:I0019759 ! lyar-zhx1 physical interaction relationship: participates_in CCO:I0019769 ! naca-zhx1 physical interaction relationship: participates_in CCO:I0019772 ! np-zhx1 physical interaction relationship: participates_in CCO:I0019776 ! pafah1b3-zhx1 physical interaction relationship: participates_in CCO:I0019804 ! psmd11-zhx1 physical interaction relationship: participates_in CCO:I0019820 ! crlz1-zhx1 physical interaction relationship: participates_in CCO:I0019826 ! sat-zhx1 physical interaction relationship: participates_in CCO:I0019833 ! serpinb9-zhx1 physical interaction relationship: participates_in CCO:I0019847 ! tardbp-zhx1 physical interaction relationship: participates_in CCO:I0019890 ! akr1c3-zhx1 physical interaction relationship: participates_in CCO:I0020038 ! idh1-zhx1 physical interaction relationship: participates_in CCO:I0020200 ! tnfrsf10c-zhx1 physical interaction relationship: participates_in CCO:I0020205 ! tollip-zhx1 physical interaction relationship: participates_in CCO:I0020215 ! wdr33-zhx1 physical interaction relationship: participates_in CCO:I0020325 ! gng11-zhx1 physical interaction relationship: participates_in CCO:I0020398 ! pex14-zhx1 physical interaction relationship: participates_in CCO:I0020404 ! pigc-zhx1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014740 ! ZHX1_HUMAN-Phosphothreonine36 relationship: transforms_into CCO:B0014741 ! ZHX1_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0014742 ! ZHX1_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0014743 ! ZHX1_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0014744 ! ZHX1_HUMAN-Phosphoserine648 relationship: transforms_into CCO:B0014745 ! ZHX1_HUMAN-Phosphothreonine682 relationship: transforms_into CCO:B0072032 ! ZHX1_HUMAN-Phosphotyrosine289 relationship: transforms_into CCO:B0072033 ! ZHX1_HUMAN-Phosphotyrosine303 [Term] id: CCO:B0005396 name: TCRG1_HUMAN def: "Transcription elongation regulator 1" [UniProtKB:O14776] synonym: "TATA box-binding protein-associated factor 2S" EXACT [UniProtKB:O14776] synonym: "Transcription factor CA150" EXACT [UniProtKB:O14776] xref: EMBL:AAB80727.1 xref: EMBL:AAI11728.1 xref: EMBL:BAD93147.1 xref: UniProtKB:O14776 xref: UniProtKB:Q2NKN2 xref: UniProtKB:Q59EA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005755 ! TCERG1_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006168 ! bard1-tcerg1-1 physical interaction relationship: participates_in CCO:I0007082 ! bard1-tcerg1 physical interaction relationship: participates_in CCO:I0016034 ! tcerg1-luc7l physical interaction relationship: participates_in CCO:I0016035 ! pias4-tcerg1 physical interaction relationship: participates_in CCO:I0016081 ! hd-tcerg1 physical interaction relationship: participates_in CCO:I0016082 ! hd-tcerg1-1 physical interaction relationship: participates_in CCO:I0016083 ! hd-tcerg1-2 physical interaction relationship: participates_in CCO:I0016095 ! tcerg1-setdb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014326 ! TCRG1_HUMAN-Phosphoserine481 relationship: transforms_into CCO:B0014327 ! TCRG1_HUMAN-Phosphothreonine489 [Term] id: CCO:B0005397 name: GIT1_HUMAN def: "ARF GTPase-activating protein GIT1" [UniProtKB:Q9Y2X7] synonym: "Cat-1" EXACT [UniProtKB:Q9Y2X7] synonym: "Cool-associated and tyrosine-phosphorylated protein 1" EXACT [UniProtKB:Q9Y2X7] synonym: "G protein-coupled receptor kinase-interactor 1" EXACT [UniProtKB:Q9Y2X7] synonym: "GRK-interacting protein 1" EXACT [UniProtKB:Q9Y2X7] xref: EMBL:AAD28046.1 xref: EMBL:AAH06227.2 xref: EMBL:AAH48196.1 xref: UniProtKB:Q86SS0 xref: UniProtKB:Q9BRJ4 xref: UniProtKB:Q9Y2X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004699 ! GIT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006169 ! bard1-git1-1 physical interaction relationship: participates_in CCO:I0007078 ! bard1-git1 physical interaction relationship: participates_in CCO:I0008043 ! rgs2-git1 physical interaction relationship: participates_in CCO:I0008143 ! pfdn1-git1 physical interaction relationship: participates_in CCO:I0008150 ! pmf1-git1 physical interaction relationship: participates_in CCO:I0008172 ! terf1-git1 physical interaction relationship: participates_in CCO:I0016049 ! ok/sw_cl_16-git1 physical interaction relationship: participates_in CCO:I0016050 ! kiaa1377-git1-1 physical interaction relationship: participates_in CCO:I0016069 ! hd-git1 physical interaction relationship: participates_in CCO:I0016070 ! hd-git1-8 physical interaction relationship: participates_in CCO:I0016237 ! hd-git1-1 colocalization relationship: participates_in CCO:I0016238 ! hd-git1-2 physical interaction relationship: participates_in CCO:I0016239 ! hd-git1-3 physical interaction relationship: participates_in CCO:I0017496 ! hd-git1-5 physical interaction relationship: participates_in CCO:I0018152 ! hd-git1-6 colocalization relationship: participates_in CCO:I0018156 ! git1-hd physical interaction relationship: participates_in CCO:I0018162 ! kiaa1377-git1 physical interaction relationship: participates_in CCO:I0018777 ! hd-git1-7 colocalization relationship: participates_in CCO:I0019240 ! hd-git1-4 physical interaction relationship: participates_in CCO:I0019658 ! ars2-git1 physical interaction relationship: participates_in CCO:I0019676 ! trib3-git1 physical interaction relationship: participates_in CCO:I0019704 ! ddx24-git1 physical interaction relationship: participates_in CCO:I0019730 ! hbxip-git1 physical interaction relationship: participates_in CCO:I0019735 ! hmox2-git1 physical interaction relationship: participates_in CCO:I0019748 ! itgb3bp-git1 physical interaction relationship: participates_in CCO:I0019876 ! wdr33-git1 physical interaction relationship: participates_in CCO:I0020004 ! c8orf33-git1 physical interaction relationship: participates_in CCO:I0020034 ! dkfzp434n1418-git1 physical interaction relationship: participates_in CCO:I0020065 ! man2a2-git1 physical interaction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0011932 ! GIT1_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0011933 ! GIT1_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0011934 ! GIT1_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0011935 ! GIT1_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0011936 ! GIT1_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0011937 ! GIT1_HUMAN-Phosphotyrosine545 relationship: transforms_into CCO:B0011938 ! GIT1_HUMAN-Phosphotyrosine554 relationship: transforms_into CCO:B0011939 ! GIT1_HUMAN-Phosphoserine592 relationship: transforms_into CCO:B0011940 ! GIT1_HUMAN-Phosphotyrosine598 relationship: transforms_into CCO:B0031327 ! GIT1_HUMAN-Phosphotyrosine224 relationship: transforms_into CCO:B0066447 ! GIT1_HUMAN-Phosphoserine373 relationship: transforms_into CCO:B0066448 ! GIT1_HUMAN-Phosphotyrosine383 relationship: transforms_into CCO:B0066449 ! GIT1_HUMAN-Phosphothreonine392 relationship: transforms_into CCO:B0066450 ! GIT1_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0066451 ! GIT1_HUMAN-Phosphoserine596 [Term] id: CCO:B0005398 name: ELP1_HUMAN def: "Elongator complex protein 1" [UniProtKB:O95163] synonym: "ELP1" EXACT [UniProtKB:O95163] synonym: "IkappaB kinase complex-associated protein" EXACT [UniProtKB:O95163] synonym: "IKK complex-associated protein" EXACT [UniProtKB:O95163] synonym: "p150" EXACT [UniProtKB:O95163] xref: EMBL:AAC64258.1 xref: EMBL:AAG43369.1 xref: EMBL:BAF82651.1 xref: EMBL:BAG50955.1 xref: EMBL:CAB43219.1 xref: EMBL:CAI39465.1 xref: EMBL:CAI40569.1 xref: EMBL:EAW59027.1 xref: UniProtKB:O95163 xref: UniProtKB:Q5JSV2 xref: UniProtKB:Q9H327 xref: UniProtKB:Q9UG87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004563 ! IKBKAP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002009 ! phosphorylase kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003481 ! RNA polymerase II transcription elongation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: located_in CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme relationship: participates_in CCO:I0006170 ! bard1-ikbkap physical interaction relationship: participates_in CCO:I0008212 ! cdkn2b-ikbkap physical interaction relationship: participates_in CCO:I0008417 ! plk2-ikbkap physical interaction relationship: participates_in CCO:I0016075 ! hd-ikbkap physical interaction relationship: participates_in CCO:I0016076 ! hd-ikbkap-1 physical interaction relationship: participates_in CCO:I0016077 ! hd-ikbkap-2 physical interaction relationship: participates_in CCO:I0016118 ! tak1-ikap physical interaction relationship: participates_in CCO:I0017161 ! nfkbia-ikbkap physical interaction relationship: participates_in CCO:I0018157 ! ikbkap-hd physical interaction relationship: participates_in CCO:I0018437 ! pbx2-ikbkap physical interaction relationship: participates_in CCO:I0019566 ! bat3-ikbkap physical interaction relationship: participates_in CCO:I0019627 ! snapap-ikbkap physical interaction relationship: participates_in CCO:I0019637 ! ttr-ikbkap physical interaction relationship: participates_in CCO:I0019687 ! cct5-ikbkap physical interaction relationship: participates_in CCO:I0019702 ! cstf2-ikbkap physical interaction relationship: participates_in CCO:I0019719 ! flj20487-ikbkap physical interaction relationship: participates_in CCO:I0020066 ! man2a2-ikbkap physical interaction relationship: participates_in CCO:I0020076 ! mrpl42-ikbkap physical interaction relationship: participates_in CCO:I0020084 ! ndufb9-ikbkap physical interaction relationship: participates_in CCO:I0020090 ! nipsnap3a-ikbkap physical interaction relationship: participates_in CCO:I0020182 ! tac3-ikbkap physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005399 name: MYST2_HUMAN def: "Histone acetyltransferase MYST2" [UniProtKB:O95251] synonym: "EC 2.3.1.48" EXACT [UniProtKB:O95251] synonym: "Histone acetyltransferase binding to ORC1" EXACT [UniProtKB:O95251] synonym: "MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2" EXACT [UniProtKB:O95251] synonym: "MYST protein 2" EXACT [UniProtKB:O95251] xref: EMBL:AAC99368.1 xref: EMBL:AAD42348.1 xref: EMBL:AAH32640.1 xref: EMBL:AAL56649.1 xref: UniProtKB:O95251 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005151 ! MYST2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006171 ! bard1-hbo1-1 physical interaction relationship: participates_in CCO:I0007079 ! bard1-hbo1 physical interaction relationship: participates_in CCO:I0008294 ! sept5-myst2 physical interaction relationship: participates_in CCO:I0014980 ! myst2-vim physical interaction relationship: participates_in CCO:I0015015 ! cep70-myst2 physical interaction relationship: participates_in CCO:I0015062 ! myst2-znf165 physical interaction relationship: participates_in CCO:I0015093 ! hook2-myst2 physical interaction relationship: participates_in CCO:I0015137 ! myst2-q96br9 physical interaction relationship: participates_in CCO:I0015493 ! myst2-ndp52 physical interaction relationship: participates_in CCO:I0015613 ! kctd13-myst2 physical interaction relationship: participates_in CCO:I0016051 ! kiaa1377-hbo1-1 physical interaction relationship: participates_in CCO:I0016103 ! vim-hbo1 physical interaction relationship: participates_in CCO:I0017273 ! ar-myst2-1 physical interaction relationship: participates_in CCO:I0017802 ! ar-myst2-2 direct interaction relationship: participates_in CCO:I0017803 ! myst2-ar direct interaction relationship: participates_in CCO:I0017971 ! ar-myst2 physical interaction relationship: participates_in CCO:I0018163 ! kiaa1377-hbo1 physical interaction relationship: participates_in CCO:I0018757 ! myst2-ar-1 direct interaction relationship: participates_in CCO:I0019684 ! cbx8-myst2 physical interaction relationship: participates_in CCO:I0019787 ! polb-myst2 physical interaction relationship: participates_in CCO:I0019824 ! sat-myst2 physical interaction relationship: participates_in CCO:I0019839 ! snapap-myst2 physical interaction relationship: participates_in CCO:I0019875 ! vim-myst2 physical interaction relationship: participates_in CCO:I0019936 ! c9orf82-myst2 physical interaction relationship: participates_in CCO:I0020118 ! ppid-myst2 physical interaction relationship: participates_in CCO:I0020144 ! rgl2-myst2 physical interaction relationship: participates_in CCO:I0020153 ! rps10-myst2 physical interaction relationship: participates_in CCO:I0020212 ! wdr33-myst2 physical interaction relationship: participates_in CCO:I0020318 ! c15orf29-myst2 physical interaction relationship: participates_in CCO:I0020392 ! pacsin1-myst2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013074 ! MYST2_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0013075 ! MYST2_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0013076 ! MYST2_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0013077 ! MYST2_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0013078 ! MYST2_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0013079 ! MYST2_HUMAN-Phosphothreonine88 relationship: transforms_into CCO:B0013080 ! MYST2_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0013081 ! MYST2_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0013082 ! MYST2_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0013083 ! MYST2_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0013084 ! MYST2_HUMAN-Phosphothreonine128 [Term] id: CCO:B0005400 name: BRD7_HUMAN def: "Bromodomain-containing protein 7" [UniProtKB:Q9NPI1] synonym: "75 kDa bromodomain protein" EXACT [UniProtKB:Q9NPI1] synonym: "Protein CELTIX-1" EXACT [UniProtKB:Q9NPI1] xref: EMBL:AAF19526.1 xref: EMBL:AAF75126.1 xref: EMBL:AAH01611.1 xref: EMBL:AAH50728.1 xref: EMBL:AAH94706.1 xref: EMBL:BAB55031.1 xref: EMBL:BAC11089.1 xref: EMBL:CAB72445.1 xref: UniProtKB:Q4VC09 xref: UniProtKB:Q8N2L9 xref: UniProtKB:Q96KA4 xref: UniProtKB:Q9BV48 xref: UniProtKB:Q9NPI1 xref: UniProtKB:Q9UH59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004189 ! BRD7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006172 ! bard1-bp465 physical interaction relationship: participates_in CCO:I0016090 ! kiaa1377-bp465 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0010865 ! BRD7_HUMAN-Phosphoserine279 [Term] id: CCO:B0005401 name: KBTB7_HUMAN def: "Kelch repeat and BTB domain-containing protein 7" [UniProtKB:Q8WVZ9] xref: EMBL:AAH22033.1 xref: EMBL:BAC03641.1 xref: EMBL:CAB66716.1 xref: EMBL:CAI16613.1 xref: EMBL:EAX08647.1 xref: UniProtKB:Q5T6Y7 xref: UniProtKB:Q8NB99 xref: UniProtKB:Q8WVZ9 xref: UniProtKB:Q9H0I6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004931 ! KBTBD7_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006173 ! bard1-kbtbd7 physical interaction [Term] id: CCO:B0005402 name: PIAS4_HUMAN def: "E3 SUMO-protein ligase PIAS4" [UniProtKB:Q8N2W9] synonym: "PIAS-gamma" EXACT [UniProtKB:Q8N2W9] synonym: "PIASy" EXACT [UniProtKB:Q8N2W9] synonym: "Protein inhibitor of activated STAT protein 4" EXACT [UniProtKB:Q8N2W9] synonym: "Protein inhibitor of activated STAT protein gamma" EXACT [UniProtKB:Q8N2W9] xref: EMBL:AAC36703.1 xref: EMBL:AAD45155.1 xref: EMBL:AAH10047.2 xref: EMBL:AAH29874.1 xref: EMBL:AAH66895.1 xref: UniProtKB:O75926 xref: UniProtKB:Q8N2W9 xref: UniProtKB:Q96G19 xref: UniProtKB:Q9UN16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005312 ! PIAS4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004172 ! SUMO ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:I0006174 ! bard1-pias4 physical interaction relationship: participates_in CCO:I0006180 ! clk1-pias4 physical interaction relationship: participates_in CCO:I0006181 ! tada3l-pias4-1 physical interaction relationship: participates_in CCO:I0006194 ! pias4-ptn physical interaction relationship: participates_in CCO:I0006806 ! tp53-pias4-3 physical interaction relationship: participates_in CCO:I0007027 ! tp53-pias4-2 physical interaction relationship: participates_in CCO:I0007081 ! tada3l-pias4 physical interaction relationship: participates_in CCO:I0015082 ! ndp52-pias4 physical interaction relationship: participates_in CCO:I0016035 ! pias4-tcerg1 physical interaction relationship: participates_in CCO:I0016043 ! gadd45g-pias4 physical interaction relationship: participates_in CCO:I0016053 ! hip2-pias4 physical interaction relationship: participates_in CCO:I0016054 ! immt-pias4 physical interaction relationship: participates_in CCO:I0016064 ! hd-pias4 physical interaction relationship: participates_in CCO:I0016065 ! hd-pias4-1 physical interaction relationship: participates_in CCO:I0016084 ! impdh2-pias4 physical interaction relationship: participates_in CCO:I0016085 ! kpnb1-pias4 physical interaction relationship: participates_in CCO:I0016089 ! mageh1-pias4 physical interaction relationship: participates_in CCO:I0016091 ! fnbp3-pias4 physical interaction relationship: participates_in CCO:I0016098 ! pias4-smt3h1 physical interaction relationship: participates_in CCO:I0016099 ! pias4-smt3h2 physical interaction relationship: participates_in CCO:I0016105 ! vim-pias4 physical interaction relationship: participates_in CCO:I0016107 ! pias4-zhx1 physical interaction relationship: participates_in CCO:I0016119 ! pias4-smt3h2-1 physical interaction relationship: participates_in CCO:I0018160 ! pias4-hd physical interaction relationship: participates_in CCO:I0018165 ! smt3h2-pias4 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0005403 name: K1377_HUMAN def: "Uncharacterized protein KIAA1377" [UniProtKB:Q9P2H0] xref: EMBL:BAA92615.1 xref: UniProtKB:Q4G0U6 xref: UniProtKB:Q9P2H0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004918 ! KIAA1377_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006175 ! bard1-kiaa1377-1 physical interaction relationship: participates_in CCO:I0006188 ! kiaa1377-kpna2 physical interaction relationship: participates_in CCO:I0007080 ! bard1-kiaa1377 physical interaction relationship: participates_in CCO:I0008016 ! kif15-kiaa1377 physical interaction relationship: participates_in CCO:I0008081 ! cdkn2b-kiaa1377 physical interaction relationship: participates_in CCO:I0008095 ! dleu1-kiaa1377 physical interaction relationship: participates_in CCO:I0008145 ! pfdn1-kiaa1377 physical interaction relationship: participates_in CCO:I0008170 ! supt5h-kiaa1377 physical interaction relationship: participates_in CCO:I0008260 ! mad2l1bp-kiaa1377 physical interaction relationship: participates_in CCO:I0008296 ! pold1-kiaa1377 physical interaction relationship: participates_in CCO:I0008307 ! ran-kiaa1377 physical interaction relationship: participates_in CCO:I0008342 ! pbk-kiaa1377 physical interaction relationship: participates_in CCO:I0008420 ! pmf1-kiaa1377 physical interaction relationship: participates_in CCO:I0008432 ! ruvbl1-kiaa1377 physical interaction relationship: participates_in CCO:I0016041 ! gadd45g-kiaa1377-1 physical interaction relationship: participates_in CCO:I0016050 ! kiaa1377-git1-1 physical interaction relationship: participates_in CCO:I0016051 ! kiaa1377-hbo1-1 physical interaction relationship: participates_in CCO:I0016071 ! hd-kiaa1377 physical interaction relationship: participates_in CCO:I0016090 ! kiaa1377-bp465 physical interaction relationship: participates_in CCO:I0016093 ! kiaa1377-htatip-1 physical interaction relationship: participates_in CCO:I0018161 ! kiaa1377-hd physical interaction relationship: participates_in CCO:I0018162 ! kiaa1377-git1 physical interaction relationship: participates_in CCO:I0018163 ! kiaa1377-hbo1 physical interaction relationship: participates_in CCO:I0018164 ! gadd45g-kiaa1377 physical interaction relationship: participates_in CCO:I0018166 ! kiaa1377-htatip physical interaction relationship: participates_in CCO:I0019544 ! rpa2-kiaa1377 physical interaction relationship: participates_in CCO:I0019597 ! itgb3bp-kiaa1377 physical interaction relationship: participates_in CCO:I0019638 ! ywhaz-kiaa1377 physical interaction relationship: participates_in CCO:I0019641 ! znf24-kiaa1377 physical interaction relationship: participates_in CCO:I0019716 ! fgfr3-kiaa1377 physical interaction relationship: participates_in CCO:I0019731 ! hbxip-kiaa1377 physical interaction relationship: participates_in CCO:I0019765 ! mapk9-kiaa1377 physical interaction relationship: participates_in CCO:I0019783 ! pdcd5-kiaa1377 physical interaction relationship: participates_in CCO:I0019849 ! tfg-kiaa1377 physical interaction relationship: participates_in CCO:I0019919 ! atrx-kiaa1377 physical interaction relationship: participates_in CCO:I0020142 ! rab27a-kiaa1377 physical interaction [Term] id: CCO:B0005404 name: SETB1_HUMAN def: "Histone-lysine N-methyltransferase SETDB1" [UniProtKB:Q15047] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q15047] synonym: "ERG-associated protein with SET domain" EXACT [UniProtKB:Q15047] synonym: "ESET" EXACT [UniProtKB:Q15047] synonym: "H3-K9-HMTase 4" EXACT [UniProtKB:Q15047] synonym: "Histone H3-K9 methyltransferase 4" EXACT [UniProtKB:Q15047] synonym: "Lysine N-methyltransferase 1E" EXACT [UniProtKB:Q15047] synonym: "SET domain bifurcated 1" EXACT [UniProtKB:Q15047] xref: EMBL:AAH09362.1 xref: EMBL:AAH28671.1 xref: EMBL:BAA06689.2 xref: EMBL:CAI13325.1 xref: EMBL:CAI13326.1 xref: EMBL:CAI13327.1 xref: EMBL:CAI13328.1 xref: EMBL:EAW53506.1 xref: UniProtKB:A6NEW2 xref: UniProtKB:Q15047 xref: UniProtKB:Q5SZD8 xref: UniProtKB:Q5SZD9 xref: UniProtKB:Q5SZE0 xref: UniProtKB:Q5SZE7 xref: UniProtKB:Q96GM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005597 ! SETDB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006176 ! bard1-setdb1 physical interaction relationship: participates_in CCO:I0008080 ! cdk4-setdb1 physical interaction relationship: participates_in CCO:I0008105 ! erh-setdb1 physical interaction relationship: participates_in CCO:I0008112 ! gps2-setdb1 physical interaction relationship: participates_in CCO:I0008133 ! mad2l1bp-setdb1 physical interaction relationship: participates_in CCO:I0008220 ! dleu1-setdb1 physical interaction relationship: participates_in CCO:I0008242 ! smpd3-setdb1 physical interaction relationship: participates_in CCO:I0016095 ! tcerg1-setdb1 physical interaction relationship: participates_in CCO:I0016100 ! smt3h2-setdb1 physical interaction relationship: participates_in CCO:I0016102 ! vim-setdb1 physical interaction relationship: participates_in CCO:I0017288 ! kiaa0911-setdb1 physical interaction relationship: participates_in CCO:I0017411 ! setdb1-dnmt3a-1 physical interaction relationship: participates_in CCO:I0017412 ! setdb1-dnmt3a-3 physical interaction relationship: participates_in CCO:I0018101 ! dnmt3a-setdb1 direct interaction relationship: participates_in CCO:I0018102 ! dnmt3a-setdb1-1 direct interaction relationship: participates_in CCO:I0018103 ! dnmt3a-setdb1-2 direct interaction relationship: participates_in CCO:I0018104 ! dnmt3a-setdb1-3 direct interaction relationship: participates_in CCO:I0018856 ! erg-setdb1-2 physical interaction relationship: participates_in CCO:I0019462 ! setdb1-dnmt3a colocalization relationship: participates_in CCO:I0019567 ! bat3-setdb1 physical interaction relationship: participates_in CCO:I0019668 ! bhlhb2-setdb1 physical interaction relationship: participates_in CCO:I0019671 ! btbd2-setdb1 physical interaction relationship: participates_in CCO:I0019677 ! trib3-setdb1 physical interaction relationship: participates_in CCO:I0019699 ! creld1-setdb1 physical interaction relationship: participates_in CCO:I0019709 ! dnmt2-setdb1 physical interaction relationship: participates_in CCO:I0019728 ! gsto1-setdb1 physical interaction relationship: participates_in CCO:I0019768 ! mrpl44-setdb1 physical interaction relationship: participates_in CCO:I0019775 ! pafah1b3-setdb1 physical interaction relationship: participates_in CCO:I0019781 ! pcdha4-setdb1 physical interaction relationship: participates_in CCO:I0019796 ! pp-setdb1 physical interaction relationship: participates_in CCO:I0019802 ! prkra-setdb1 physical interaction relationship: participates_in CCO:I0019803 ! psmd11-setdb1 physical interaction relationship: participates_in CCO:I0019812 ! rnf10-setdb1 physical interaction relationship: participates_in CCO:I0019825 ! sat-setdb1 physical interaction relationship: participates_in CCO:I0019832 ! serpinb9-setdb1 physical interaction relationship: participates_in CCO:I0019836 ! sma3-setdb1 physical interaction relationship: participates_in CCO:I0019844 ! sult1e1-setdb1 physical interaction relationship: participates_in CCO:I0019846 ! tardbp-setdb1 physical interaction relationship: participates_in CCO:I0019860 ! tk1-setdb1 physical interaction relationship: participates_in CCO:I0019870 ! ttr-setdb1 physical interaction relationship: participates_in CCO:I0019874 ! ulk2-setdb1 physical interaction relationship: participates_in CCO:I0019879 ! zfp64-setdb1 physical interaction relationship: participates_in CCO:I0019886 ! znf24-setdb1 physical interaction relationship: participates_in CCO:I0019893 ! aof2-setdb1 physical interaction relationship: participates_in CCO:I0019901 ! asah1-setdb1 physical interaction relationship: participates_in CCO:I0019927 ! brix-setdb1 physical interaction relationship: participates_in CCO:I0019933 ! c7orf19-setdb1 physical interaction relationship: participates_in CCO:I0019941 ! cbx8-setdb1 physical interaction relationship: participates_in CCO:I0020027 ! hmox2-setdb1 physical interaction relationship: participates_in CCO:I0020028 ! olfml3-setdb1 physical interaction relationship: participates_in CCO:I0020033 ! hspb3-setdb1 physical interaction relationship: participates_in CCO:I0020072 ! mgc5352-setdb1 physical interaction relationship: participates_in CCO:I0020091 ! nipsnap3a-setdb1 physical interaction relationship: participates_in CCO:I0020100 ! pdcd8-setdb1 physical interaction relationship: participates_in CCO:I0020108 ! phf10-setdb1 physical interaction relationship: participates_in CCO:I0020115 ! plekha4-setdb1 physical interaction relationship: participates_in CCO:I0020116 ! pola2-setdb1 physical interaction relationship: participates_in CCO:I0020127 ! prei3-setdb1 physical interaction relationship: participates_in CCO:I0020134 ! ptprs-setdb1 physical interaction relationship: participates_in CCO:I0020135 ! qtrt1-setdb1 physical interaction relationship: participates_in CCO:I0020158 ! s100a10-setdb1 physical interaction relationship: participates_in CCO:I0020195 ! thap8-setdb1 physical interaction relationship: participates_in CCO:I0020204 ! tollip-setdb1 physical interaction relationship: participates_in CCO:I0020206 ! tpi1-setdb1 physical interaction relationship: participates_in CCO:I0020207 ! trbv21_1-setdb1 physical interaction relationship: participates_in CCO:I0020258 ! c11orf1-setdb1 physical interaction relationship: participates_in CCO:I0020282 ! dap-setdb1 physical interaction relationship: participates_in CCO:I0020409 ! ppp1r8-setdb1 physical interaction relationship: participates_in CCO:I0020453 ! slc38a3-setdb1 physical interaction relationship: participates_in CCO:I0020486 ! tob1-setdb1 physical interaction relationship: participates_in CCO:I0020494 ! usp11-setdb1 physical interaction relationship: participates_in CCO:I0020681 ! trim16-setdb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014020 ! SETB1_HUMAN-Phosphothreonine838 relationship: transforms_into CCO:B0014021 ! SETB1_HUMAN-Phosphoserine1179 relationship: transforms_into CCO:B0014022 ! SETB1_HUMAN-Phosphothreonine1180 relationship: transforms_into CCO:B0014023 ! SETB1_HUMAN-Phosphoserine1190 relationship: transforms_into CCO:B0048390 ! SETB1_HUMAN-Phosphoserine1066 [Term] id: CCO:B0005405 name: GASP2_HUMAN def: "G-protein coupled receptor-associated sorting protein 2" [UniProtKB:Q96D09] synonym: "GASP-2" EXACT [UniProtKB:Q96D09] xref: EMBL:AAH13576.1 xref: EMBL:AAH36772.1 xref: EMBL:BAC04010.1 xref: EMBL:CAI43060.1 xref: UniProtKB:Q8NAB4 xref: UniProtKB:Q96D09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004685 ! GPRASP2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006178 ! bard1-gprasp2 physical interaction relationship: participates_in CCO:I0006195 ! ptn-gprasp2 physical interaction relationship: participates_in CCO:I0016062 ! hd-gprasp2 physical interaction relationship: participates_in CCO:I0016063 ! hd-gprasp2-1 physical interaction [Term] id: CCO:B0005406 name: MAGH1_HUMAN def: "Melanoma-associated antigen H1" [UniProtKB:Q9H213] synonym: "Apoptosis-related protein 1" EXACT [UniProtKB:Q9H213] synonym: "APR-1" EXACT [UniProtKB:Q9H213] synonym: "MAGE-H1 antigen" EXACT [UniProtKB:Q9H213] synonym: "Restin" EXACT [UniProtKB:Q9H213] xref: EMBL:AAD31314.4 xref: EMBL:AAG38608.1 xref: EMBL:AAH11954.1 xref: EMBL:CAI41100.1 xref: UniProtKB:Q5JRJ3 xref: UniProtKB:Q9H213 xref: UniProtKB:Q9Y5M2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005021 ! MAGEH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006182 ! tada3l-mageh1 physical interaction relationship: participates_in CCO:I0006187 ! mageh1-kpna2 physical interaction relationship: participates_in CCO:I0014953 ! mageh1-moap1 physical interaction relationship: participates_in CCO:I0016089 ! mageh1-pias4 physical interaction relationship: participates_in CCO:I0019944 ! cdk5rap2-mageh1 physical interaction [Term] id: CCO:B0005407 name: HD_HUMAN def: "Huntingtin" [UniProtKB:P42858] synonym: "HD protein" EXACT [UniProtKB:P42858] synonym: "Huntington disease protein" EXACT [UniProtKB:P42858] xref: EMBL:AAA52702.1 xref: EMBL:AAB38240.1 xref: EMBL:BAA36753.1 xref: EMBL:CAA89024.1 xref: EMBL:CAA89025.1 xref: EMBL:CAA89839.1 xref: UniProtKB:P42858 xref: UniProtKB:Q9UQB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013377 ! HTT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006183 ! hd-mtss1 physical interaction relationship: participates_in CCO:I0006184 ! hd-mtss1-1 physical interaction relationship: participates_in CCO:I0006185 ! hd-mtss1-2 physical interaction relationship: participates_in CCO:I0007241 ! hd-p53-2 physical interaction relationship: participates_in CCO:I0007737 ! hd-p53-3 physical interaction relationship: participates_in CCO:I0007738 ! hd-p53-4 physical interaction relationship: participates_in CCO:I0007849 ! hd-p53-1 physical interaction relationship: participates_in CCO:I0016037 ! hd-crmp1 physical interaction relationship: participates_in CCO:I0016055 ! hd-fnbp3 physical interaction relationship: participates_in CCO:I0016056 ! hd-fnbp3-1 physical interaction relationship: participates_in CCO:I0016057 ! hd-fnbp3-2 physical interaction relationship: participates_in CCO:I0016058 ! hd-hip1 physical interaction relationship: participates_in CCO:I0016059 ! hd-sh3gl3 physical interaction relationship: participates_in CCO:I0016060 ! hd-sh3gl3-1 physical interaction relationship: participates_in CCO:I0016061 ! hd-sh3gl3-2 physical interaction relationship: participates_in CCO:I0016062 ! hd-gprasp2 physical interaction relationship: participates_in CCO:I0016063 ! hd-gprasp2-1 physical interaction relationship: participates_in CCO:I0016064 ! hd-pias4 physical interaction relationship: participates_in CCO:I0016065 ! hd-pias4-1 physical interaction relationship: participates_in CCO:I0016066 ! hd-soh1 physical interaction relationship: participates_in CCO:I0016067 ! hd-soh1-1 physical interaction relationship: participates_in CCO:I0016068 ! hd-soh1-2 physical interaction relationship: participates_in CCO:I0016069 ! hd-git1 physical interaction relationship: participates_in CCO:I0016070 ! hd-git1-8 physical interaction relationship: participates_in CCO:I0016071 ! hd-kiaa1377 physical interaction relationship: participates_in CCO:I0016072 ! hd-utp14a physical interaction relationship: participates_in CCO:I0016073 ! hd-fez1 physical interaction relationship: participates_in CCO:I0016074 ! hd-fez1-1 physical interaction relationship: participates_in CCO:I0016075 ! hd-ikbkap physical interaction relationship: participates_in CCO:I0016076 ! hd-ikbkap-1 physical interaction relationship: participates_in CCO:I0016077 ! hd-ikbkap-2 physical interaction relationship: participates_in CCO:I0016078 ! hd-pfn2 physical interaction relationship: participates_in CCO:I0016079 ! hd-pfn2-1 physical interaction relationship: participates_in CCO:I0016080 ! hd-pfn2-2 physical interaction relationship: participates_in CCO:I0016081 ! hd-tcerg1 physical interaction relationship: participates_in CCO:I0016082 ! hd-tcerg1-1 physical interaction relationship: participates_in CCO:I0016083 ! hd-tcerg1-2 physical interaction relationship: participates_in CCO:I0016087 ! hd-g22p1 physical interaction relationship: participates_in CCO:I0016088 ! hd-g22p1-1 physical interaction relationship: participates_in CCO:I0016237 ! hd-git1-1 colocalization relationship: participates_in CCO:I0016238 ! hd-git1-2 physical interaction relationship: participates_in CCO:I0016239 ! hd-git1-3 physical interaction relationship: participates_in CCO:I0017496 ! hd-git1-5 physical interaction relationship: participates_in CCO:I0018038 ! hip14-hd-2 palmitoylation relationship: participates_in CCO:I0018152 ! hd-git1-6 colocalization relationship: participates_in CCO:I0018153 ! soh1-hd physical interaction relationship: participates_in CCO:I0018154 ! crmp1-hd physical interaction relationship: participates_in CCO:I0018155 ! fez1-hd physical interaction relationship: participates_in CCO:I0018156 ! git1-hd physical interaction relationship: participates_in CCO:I0018157 ! ikbkap-hd physical interaction relationship: participates_in CCO:I0018158 ! g22p1-hd physical interaction relationship: participates_in CCO:I0018159 ! pfn2-hd physical interaction relationship: participates_in CCO:I0018160 ! pias4-hd physical interaction relationship: participates_in CCO:I0018161 ! kiaa1377-hd physical interaction relationship: participates_in CCO:I0018305 ! hd-crebbp-1 physical interaction relationship: participates_in CCO:I0018306 ! hd-crebbp-2 physical interaction relationship: participates_in CCO:I0018521 ! cnas3-atx2 physical interaction relationship: participates_in CCO:I0018777 ! hd-git1-7 colocalization relationship: participates_in CCO:I0019240 ! hd-git1-4 physical interaction relationship: participates_in CCO:I0020622 ! pdk2-hd physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0012175 ! HD_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0012176 ! HD_HUMAN-Phosphoserine1876 relationship: transforms_into CCO:B0041143 ! HD_HUMAN-Phosphoserine434 relationship: transforms_into CCO:B0066789 ! HD_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0066790 ! HD_HUMAN-Phosphoserine1872 [Term] id: CCO:B0005408 name: Q8NI70_HUMAN def: "OK/SW-CL.16" [UniProtKB:Q8NI70] xref: EMBL:BAB93516.1 xref: UniProtKB:Q8NI70 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006027 ! OK/SW-cl.16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006186 ! ok/sw_cl_16-kpna2 physical interaction relationship: participates_in CCO:I0016044 ! gadd45g-ok/sw_cl_16 physical interaction relationship: participates_in CCO:I0016049 ! ok/sw_cl_16-git1 physical interaction relationship: participates_in CCO:I0016097 ! ok/sw_cl_16-sh3gl3 physical interaction [Term] id: CCO:B0005409 name: IMB1_HUMAN def: "Importin subunit beta-1" [UniProtKB:Q14974] synonym: "Importin-90" EXACT [UniProtKB:Q14974] synonym: "Karyopherin subunit beta-1" EXACT [UniProtKB:Q14974] synonym: "Nuclear factor P97" EXACT [UniProtKB:Q14974] xref: EMBL:AAA82869.1 xref: EMBL:AAC41763.1 xref: EMBL:AAH03572.1 xref: EMBL:AAH24045.1 xref: EMBL:AAH36703.1 xref: UniProtKB:Q14637 xref: UniProtKB:Q14974 xref: UniProtKB:Q96J27 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004889 ! KPNB1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001742 ! nuclear localization sequence binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006189 ! kpnb1-ptn physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0006829 ! ran-xpot-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016085 ! kpnb1-pias4 physical interaction relationship: participates_in CCO:I0016851 ! relb-kpnb1 physical interaction relationship: participates_in CCO:I0017058 ! tradd-kpnb1 physical interaction relationship: participates_in CCO:I0017133 ! traf6-kpnb1 physical interaction relationship: participates_in CCO:I0017976 ! eif4e-importinalpha- physical interaction relationship: participates_in CCO:I0019348 ! smndc1-kpnb1 physical interaction relationship: participates_in CCO:I0019349 ! smndc1-kpnb1-2 physical interaction relationship: transforms_into CCO:B0012379 ! IMB1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0067087 ! IMB1_HUMAN-Phosphoserine12 [Term] id: CCO:B0005410 name: KU70_HUMAN def: "ATP-dependent DNA helicase 2 subunit 1" [UniProtKB:P12956] synonym: "70 kDa subunit of Ku antigen" EXACT [UniProtKB:P12956] synonym: "ATP-dependent DNA helicase II 70 kDa subunit" EXACT [UniProtKB:P12956] synonym: "CTC box-binding factor 75 kDa subunit" EXACT [UniProtKB:P12956] synonym: "CTC75" EXACT [UniProtKB:P12956] synonym: "CTCBF" EXACT [UniProtKB:P12956] synonym: "DNA repair protein XRCC6" EXACT [UniProtKB:P12956] synonym: "Ku70" EXACT [UniProtKB:P12956] synonym: "Lupus Ku autoantigen protein p70" EXACT [UniProtKB:P12956] synonym: "Thyroid-lupus autoantigen" EXACT [UniProtKB:P12956] synonym: "TLAA" EXACT [UniProtKB:P12956] xref: EMBL:AAA36155.1 xref: EMBL:AAA51733.1 xref: EMBL:AAA61177.1 xref: EMBL:AAB22381.1 xref: EMBL:AAH08343.1 xref: EMBL:AAH10034.1 xref: EMBL:AAH12154.1 xref: EMBL:AAH18259.1 xref: EMBL:AAH72449.1 xref: EMBL:AAW34364.1 xref: EMBL:CAB46206.1 xref: EMBL:CAG47015.1 xref: UniProtKB:P12956 xref: UniProtKB:Q6FG89 xref: UniProtKB:Q9UCQ2 xref: UniProtKB:Q9UCQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004965 ! XRCC6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006190 ! tada3l-g22p1 physical interaction relationship: participates_in CCO:I0006264 ! tcf7l2-parp1-5 physical interaction relationship: participates_in CCO:I0006464 ! tcf7l2-parp1 physical interaction relationship: participates_in CCO:I0007054 ! tcf7l2-parp1-1 physical interaction relationship: participates_in CCO:I0007055 ! tcf7l2-g22p1 physical interaction relationship: participates_in CCO:I0007056 ! tcf7l2-ctnnb1-7 physical interaction relationship: participates_in CCO:I0007131 ! terf2ip-rad50 physical interaction relationship: participates_in CCO:I0007320 ! parp1-tcf7l2-1 physical interaction relationship: participates_in CCO:I0007321 ! g22p1-parp1 physical interaction relationship: participates_in CCO:I0007482 ! tcf7l2-ctnnb1-8 physical interaction relationship: participates_in CCO:I0007483 ! g22p1-tcf7l2 physical interaction relationship: participates_in CCO:I0007517 ! tcf7l2-g22p1-1 physical interaction relationship: participates_in CCO:I0007575 ! g22p1-centd2-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008239 ! smpd3-g22p1 physical interaction relationship: participates_in CCO:I0008280 ! nhp2l1-g22p1 physical interaction relationship: participates_in CCO:I0008369 ! cdca5-g22p1 physical interaction relationship: participates_in CCO:I0008373 ! centd2-g22p1 physical interaction relationship: participates_in CCO:I0008425 ! rbbp4-g22p1 physical interaction relationship: participates_in CCO:I0015955 ! wrn-g22p1-2 physical interaction relationship: participates_in CCO:I0016036 ! cltc-g22p1 physical interaction relationship: participates_in CCO:I0016086 ! cct3-g22p1 physical interaction relationship: participates_in CCO:I0016087 ! hd-g22p1 physical interaction relationship: participates_in CCO:I0016088 ! hd-g22p1-1 physical interaction relationship: participates_in CCO:I0016110 ! g22p1-xrcc5-1 direct interaction relationship: participates_in CCO:I0016111 ! g22p1-xrcc5-2 direct interaction relationship: participates_in CCO:I0017312 ! parp1-xrcc5-1 physical interaction relationship: participates_in CCO:I0017981 ! parp1-wrn-2 adp ribosylation relationship: participates_in CCO:I0018158 ! g22p1-hd physical interaction relationship: participates_in CCO:I0018203 ! wrn-g22p1-1 physical interaction relationship: participates_in CCO:I0018335 ! xrcc5-g22p1-1 phosphorylation relationship: participates_in CCO:I0018336 ! wrn-g22p1-3 phosphorylation relationship: participates_in CCO:I0018730 ! parp1-g22p1 physical interaction relationship: participates_in CCO:I0019222 ! wrn-xrcc5-1 physical interaction relationship: participates_in CCO:I0019397 ! wrn-g22p1-4 physical interaction relationship: participates_in CCO:I0019434 ! ku70_80_human direct interaction relationship: participates_in CCO:I0019484 ! wrn-xrcc5-2 physical interaction relationship: participates_in CCO:I0019503 ! wrn-xrcc5-3 physical interaction relationship: participates_in CCO:I0019504 ! wrn-xrcc5-4 physical interaction relationship: participates_in CCO:I0019665 ! atp6v1e1-g22p1 physical interaction relationship: participates_in CCO:I0019773 ! paep-g22p1 physical interaction relationship: participates_in CCO:I0019774 ! pafah1b3-g22p1 physical interaction relationship: participates_in CCO:I0019817 ! rplp1-g22p1 physical interaction relationship: participates_in CCO:I0019830 ! serpinb9-g22p1 physical interaction relationship: participates_in CCO:I0019878 ! ywhaz-g22p1 physical interaction relationship: participates_in CCO:I0019888 ! abcd4-g22p1 physical interaction relationship: participates_in CCO:I0019935 ! c9orf46-g22p1 physical interaction relationship: participates_in CCO:I0020051 ! kiaa0182-g22p1 physical interaction relationship: participates_in CCO:I0020092 ! nit1-g22p1 physical interaction relationship: participates_in CCO:I0020102 ! pecam1-g22p1 physical interaction relationship: participates_in CCO:I0020157 ! rras2-g22p1 physical interaction relationship: participates_in CCO:I0020173 ! snta1-g22p1 physical interaction relationship: participates_in CCO:I0020219 ! acd-g22p1 physical interaction relationship: participates_in CCO:I0020319 ! fmnl1-g22p1 physical interaction relationship: participates_in CCO:I0020384 ! notch1-g22p1 physical interaction relationship: participates_in CCO:I0020399 ! pgam1-g22p1 physical interaction relationship: participates_in CCO:I0020518 ! c16orf34-g22p1 physical interaction relationship: participates_in CCO:I0020629 ! por-g22p1 physical interaction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012648 ! KU70_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0012649 ! KU70_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0012650 ! KU70_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0012651 ! KU70_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0012652 ! KU70_HUMAN-Phosphoserine222 [Term] id: CCO:B0005411 name: GA45G_HUMAN def: "Growth arrest and DNA-damage-inducible protein GADD45 gamma" [UniProtKB:O95257] synonym: "Cytokine-responsive protein CR6" EXACT [UniProtKB:O95257] synonym: "DDIT-2" EXACT [UniProtKB:O95257] synonym: "DNA-damage-inducible transcript 2" EXACT [UniProtKB:O95257] xref: EMBL:AAC83329.1 xref: EMBL:AAD28544.1 xref: EMBL:AAF73468.1 xref: EMBL:AAH00465.1 xref: EMBL:AAH19325.1 xref: EMBL:AAK00414.1 xref: EMBL:AAM00007.1 xref: EMBL:AAP35898.1 xref: UniProtKB:O95257 xref: UniProtKB:Q9C076 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004676 ! GADD45G_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006191 ! gadd45g-ptn physical interaction relationship: participates_in CCO:I0007532 ! map3k4-gadd45-3 physical interaction relationship: participates_in CCO:I0014958 ! c21orf6-gadd45g physical interaction relationship: participates_in CCO:I0015043 ! gadd45g-tsnax physical interaction relationship: participates_in CCO:I0016038 ! gadd45g-eef1a1 physical interaction relationship: participates_in CCO:I0016039 ! gadd45g-eef1g physical interaction relationship: participates_in CCO:I0016040 ! gadd45g-dkfzp564o052 physical interaction relationship: participates_in CCO:I0016041 ! gadd45g-kiaa1377-1 physical interaction relationship: participates_in CCO:I0016042 ! gadd45g-luc7l physical interaction relationship: participates_in CCO:I0016043 ! gadd45g-pias4 physical interaction relationship: participates_in CCO:I0016044 ! gadd45g-ok/sw_cl_16 physical interaction relationship: participates_in CCO:I0016045 ! gadd45g-soh1 physical interaction relationship: participates_in CCO:I0016046 ! gadd45g-luc7l2 physical interaction relationship: participates_in CCO:I0016048 ! gadd45g-gdf9 physical interaction relationship: participates_in CCO:I0016052 ! gadd45g-utp14a-1 physical interaction relationship: participates_in CCO:I0016092 ! gadd45g-htatip-1 physical interaction relationship: participates_in CCO:I0016094 ! gadd45g-ptprk physical interaction relationship: participates_in CCO:I0018164 ! gadd45g-kiaa1377 physical interaction relationship: participates_in CCO:I0018167 ! gadd45g-htatip physical interaction relationship: participates_in CCO:I0018168 ! gadd45g-utp14a physical interaction relationship: participates_in CCO:I0018169 ! soh1-gadd45g physical interaction relationship: participates_in CCO:P0000409 ! activation of MAPKKK activity [Term] id: CCO:B0005412 name: TP53B_HUMAN def: "Tumor suppressor p53-binding protein 1" [UniProtKB:Q12888] synonym: "53BP1" EXACT [UniProtKB:Q12888] synonym: "p53-binding protein 1" EXACT [UniProtKB:Q12888] synonym: "p53BP1" EXACT [UniProtKB:Q12888] xref: EMBL:AAA21596.1 xref: EMBL:AAC62018.1 xref: EMBL:AAI12162.1 xref: EMBL:AAW69392.1 xref: EMBL:BAE06107.1 xref: EMBL:CAD97660.1 xref: UniProtKB:Q12888 xref: UniProtKB:Q2M1Z7 xref: UniProtKB:Q4LE46 xref: UniProtKB:Q5FWZ3 xref: UniProtKB:Q7Z3U4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005815 ! TP53BP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006198 ! h2ax-tp53bp1-1 physical interaction relationship: participates_in CCO:I0006960 ! mdc1-atm-1 physical interaction relationship: participates_in CCO:I0007166 ! tp53-tp53bp1-1 direct interaction relationship: participates_in CCO:I0007272 ! nek1-tp53bp1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014450 ! TP53B_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0014451 ! TP53B_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0014452 ! TP53B_HUMAN-Phosphothreonine302 relationship: transforms_into CCO:B0014453 ! TP53B_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0014454 ! TP53B_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0014455 ! TP53B_HUMAN-Phosphoserine500 relationship: transforms_into CCO:B0014456 ! TP53B_HUMAN-Phosphoserine523 relationship: transforms_into CCO:B0014457 ! TP53B_HUMAN-Phosphoserine525 relationship: transforms_into CCO:B0014458 ! TP53B_HUMAN-Phosphothreonine543 relationship: transforms_into CCO:B0014459 ! TP53B_HUMAN-Phosphothreonine548 relationship: transforms_into CCO:B0014460 ! TP53B_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0014461 ! TP53B_HUMAN-Phosphoserine566 relationship: transforms_into CCO:B0014462 ! TP53B_HUMAN-Phosphoserine580 relationship: transforms_into CCO:B0014463 ! TP53B_HUMAN-Phosphoserine625 relationship: transforms_into CCO:B0014464 ! TP53B_HUMAN-Phosphoserine635 relationship: transforms_into CCO:B0014465 ! TP53B_HUMAN-Phosphoserine639 relationship: transforms_into CCO:B0014466 ! TP53B_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0014467 ! TP53B_HUMAN-Phosphoserine659 relationship: transforms_into CCO:B0014468 ! TP53B_HUMAN-Phosphoserine660 relationship: transforms_into CCO:B0014469 ! TP53B_HUMAN-Phosphoserine662 relationship: transforms_into CCO:B0014470 ! TP53B_HUMAN-Phosphothreonine750 relationship: transforms_into CCO:B0014471 ! TP53B_HUMAN-Phosphoserine751 relationship: transforms_into CCO:B0014472 ! TP53B_HUMAN-Phosphoserine754 relationship: transforms_into CCO:B0014473 ! TP53B_HUMAN-Phosphoserine755 relationship: transforms_into CCO:B0014474 ! TP53B_HUMAN-Phosphoserine771 relationship: transforms_into CCO:B0014475 ! TP53B_HUMAN-Phosphoserine782 relationship: transforms_into CCO:B0014476 ! TP53B_HUMAN-Phosphoserine784 relationship: transforms_into CCO:B0014477 ! TP53B_HUMAN-Phosphoserine831 relationship: transforms_into CCO:B0014478 ! TP53B_HUMAN-Phosphothreonine855 relationship: transforms_into CCO:B0014479 ! TP53B_HUMAN-Phosphoserine892 relationship: transforms_into CCO:B0014480 ! TP53B_HUMAN-Phosphoserine993 relationship: transforms_into CCO:B0014481 ! TP53B_HUMAN-Phosphothreonine996 relationship: transforms_into CCO:B0014482 ! TP53B_HUMAN-Phosphoserine999 relationship: transforms_into CCO:B0014483 ! TP53B_HUMAN-Phosphoserine1002 relationship: transforms_into CCO:B0014484 ! TP53B_HUMAN-Phosphoserine1028 relationship: transforms_into CCO:B0014485 ! TP53B_HUMAN-Phosphothreonine1056 relationship: transforms_into CCO:B0014486 ! TP53B_HUMAN-Phosphoserine1068 relationship: transforms_into CCO:B0014487 ! TP53B_HUMAN-Phosphoserine1094 relationship: transforms_into CCO:B0014488 ! TP53B_HUMAN-Phosphoserine1104 relationship: transforms_into CCO:B0014489 ! TP53B_HUMAN-Phosphoserine1114 relationship: transforms_into CCO:B0014490 ! TP53B_HUMAN-Phosphothreonine1171 relationship: transforms_into CCO:B0014491 ! TP53B_HUMAN-Phosphothreonine1214 relationship: transforms_into CCO:B0014492 ! TP53B_HUMAN-Phosphoserine1216 relationship: transforms_into CCO:B0014493 ! TP53B_HUMAN-Phosphoserine1219 relationship: transforms_into CCO:B0014494 ! TP53B_HUMAN-Phosphoserine1290 relationship: transforms_into CCO:B0014495 ! TP53B_HUMAN-Phosphoserine1316 relationship: transforms_into CCO:B0014496 ! TP53B_HUMAN-Phosphoserine1317 relationship: transforms_into CCO:B0014497 ! TP53B_HUMAN-Phosphoserine1320 relationship: transforms_into CCO:B0014498 ! TP53B_HUMAN-Phosphoserine1362 relationship: transforms_into CCO:B0014499 ! TP53B_HUMAN-Phosphoserine1426 relationship: transforms_into CCO:B0014500 ! TP53B_HUMAN-Phosphoserine1430 relationship: transforms_into CCO:B0014501 ! TP53B_HUMAN-Phosphoserine1631 relationship: transforms_into CCO:B0014502 ! TP53B_HUMAN-Phosphoserine1634 relationship: transforms_into CCO:B0014503 ! TP53B_HUMAN-Phosphoserine1635 relationship: transforms_into CCO:B0014504 ! TP53B_HUMAN-Phosphothreonine1638 relationship: transforms_into CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: transforms_into CCO:B0014506 ! TP53B_HUMAN-Phosphoserine1673 relationship: transforms_into CCO:B0014507 ! TP53B_HUMAN-Phosphoserine1678 relationship: transforms_into CCO:B0014508 ! TP53B_HUMAN-Phosphoserine1701 relationship: transforms_into CCO:B0014509 ! TP53B_HUMAN-Phosphoserine1705 relationship: transforms_into CCO:B0032859 ! TP53B_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0032860 ! TP53B_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0032861 ! TP53B_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0032862 ! TP53B_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0048415 ! TP53B_HUMAN-Phosphoserine1462 relationship: transforms_into CCO:B0071457 ! TP53B_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0071458 ! TP53B_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0071459 ! TP53B_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0071460 ! TP53B_HUMAN-Phosphoserine398 relationship: transforms_into CCO:B0071461 ! TP53B_HUMAN-Phosphoserine809 relationship: transforms_into CCO:B0071462 ! TP53B_HUMAN-Phosphoserine876 relationship: transforms_into CCO:B0071463 ! TP53B_HUMAN-Phosphoserine877 relationship: transforms_into CCO:B0071464 ! TP53B_HUMAN-Phosphoserine1101 relationship: transforms_into CCO:B0071465 ! TP53B_HUMAN-Phosphoserine1368 relationship: transforms_into CCO:B0071466 ! TP53B_HUMAN-Phosphothreonine1372 relationship: transforms_into CCO:B0071467 ! TP53B_HUMAN-Phosphoserine1435 relationship: transforms_into CCO:B0071468 ! TP53B_HUMAN-Phosphothreonine1609 relationship: transforms_into CCO:B0071469 ! TP53B_HUMAN-Phosphoserine1618 relationship: transforms_into CCO:B0071470 ! TP53B_HUMAN-Phosphothreonine1672 relationship: transforms_into CCO:B0071471 ! TP53B_HUMAN-Phosphothreonine1709 [Term] id: CCO:B0005413 name: 1433Z_HUMAN def: "14-3-3 protein zeta/delta" [UniProtKB:P63104] synonym: "KCIP-1" EXACT [UniProtKB:P63104] synonym: "Protein kinase C inhibitor protein 1" EXACT [UniProtKB:P63104] xref: EMBL:AAA36446.1 xref: EMBL:AAC52052.1 xref: EMBL:AAH03623.3 xref: EMBL:AAH51814.1 xref: EMBL:AAH63824.2 xref: EMBL:AAH68456.2 xref: EMBL:AAH72426.2 xref: EMBL:AAH73141.1 xref: EMBL:AAH83508.2 xref: EMBL:AAH99904.1 xref: EMBL:AAI01484.1 xref: EMBL:AAI08282.1 xref: EMBL:AAI11952.1 xref: UniProtKB:P29213 xref: UniProtKB:P29312 xref: UniProtKB:P63104 xref: UniProtKB:Q32P43 xref: UniProtKB:Q5XJ08 xref: UniProtKB:Q6GPI2 xref: UniProtKB:Q6IN74 xref: UniProtKB:Q6NUR9 xref: UniProtKB:Q6P3U9 xref: UniProtKB:Q86V33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003998 ! YWHAZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006203 ! abl1-ywhaz-1 physical interaction relationship: participates_in CCO:I0006258 ! qsk-ywhaz-3 physical interaction relationship: participates_in CCO:I0006282 ! ywhaz-egfr-1 physical interaction relationship: participates_in CCO:I0006307 ! abl1-ywhab-1 physical interaction relationship: participates_in CCO:I0006605 ! cdc5l-ywhaz physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007180 ! snf1lk-ywhaz-1 physical interaction relationship: participates_in CCO:I0007183 ! snf1lk-ywhaz-2 direct interaction relationship: participates_in CCO:I0007212 ! ywhaz-pard3-1 physical interaction relationship: participates_in CCO:I0007214 ! pard6a-ywhaz-1 physical interaction relationship: participates_in CCO:I0007216 ! pard6b-ywhaz-1 physical interaction relationship: participates_in CCO:I0007218 ! pard3-ywhaz-1 physical interaction relationship: participates_in CCO:I0007837 ! qsk-ywhaz-2 physical interaction relationship: participates_in CCO:I0007845 ! ywhaz-egfr-2 colocalization relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0016543 ! ikbkg-ywhaz physical interaction relationship: participates_in CCO:I0017231 ! map3k3-ywhaz physical interaction relationship: participates_in CCO:I0017351 ! ywhaz-cof1-1 physical interaction relationship: participates_in CCO:I0017354 ! map3k5-ywhaz-1 physical interaction relationship: participates_in CCO:I0017355 ! map3k5-ywhab-1 physical interaction relationship: participates_in CCO:I0017477 ! disc1-ywhaz-1 physical interaction relationship: participates_in CCO:I0017495 ! ywhaz-cof1-2 physical interaction relationship: participates_in CCO:I0017497 ! ywhaz-map3k5-1 physical interaction relationship: participates_in CCO:I0017821 ! disc1-ywhaz physical interaction relationship: participates_in CCO:I0017827 ! qsk-ywhaz-4 direct interaction relationship: participates_in CCO:I0017828 ! raf1-ywhaz-2 direct interaction relationship: participates_in CCO:I0018268 ! qsk-ywhaz-1 physical interaction relationship: participates_in CCO:I0018270 ! mark1-ywhaz-1 physical interaction relationship: participates_in CCO:I0018271 ! mark2-ywhaz-2 physical interaction relationship: participates_in CCO:I0018272 ! mark3-ywhaz-1 physical interaction relationship: participates_in CCO:I0018273 ! mark4-ywhaz-3 physical interaction relationship: participates_in CCO:I0018274 ! qsk-ywhaz-5 direct interaction relationship: participates_in CCO:I0018288 ! ywhaz-prkci-1 physical interaction relationship: participates_in CCO:I0018290 ! ywhaz-mark4-1 physical interaction relationship: participates_in CCO:I0018291 ! mark4-ywhaz-1 physical interaction relationship: participates_in CCO:I0018622 ! app-nsf-3 physical interaction relationship: participates_in CCO:I0018643 ! stk25-ywhaz -2 phosphorylation relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:I0019345 ! raf1-ywhaz-1 physical interaction relationship: participates_in CCO:I0019356 ! mark2-ywhaz-1 physical interaction relationship: participates_in CCO:I0019384 ! stk25-ywhaz -1 phosphorylation relationship: participates_in CCO:I0019638 ! ywhaz-kiaa1377 physical interaction relationship: participates_in CCO:I0019878 ! ywhaz-g22p1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010373 ! 1433Z_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0010374 ! 1433Z_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0010375 ! 1433Z_HUMAN-Phosphothreonine232 [Term] id: CCO:B0005414 name: SMCA4_HUMAN def: "Probable global transcription activator SNF2L4" [UniProtKB:P51532] synonym: "ATP-dependent helicase SMARCA4" EXACT [UniProtKB:P51532] synonym: "Brahma protein homolog 1" EXACT [UniProtKB:P51532] synonym: "BRG-1 protein" EXACT [UniProtKB:P51532] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P51532] synonym: "Mitotic growth and transcription activator" EXACT [UniProtKB:P51532] synonym: "SNF2-beta" EXACT [UniProtKB:P51532] synonym: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4" EXACT [UniProtKB:P51532] xref: EMBL:AAB40977.1 xref: EMBL:AAC97986.1 xref: EMBL:AAC97987.1 xref: EMBL:AAG24789.1 xref: EMBL:BAA05143.1 xref: UniProtKB:O95052 xref: UniProtKB:P51532 xref: UniProtKB:Q9HBD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005631 ! SMARCA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0006322 ! pb1-arid2-4 physical interaction relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:I0006977 ! smarca4-pb1-arid2-2 physical interaction relationship: participates_in CCO:I0007259 ! arid2-pb1-1 physical interaction relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007356 ! pb1-arid2-3 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0016249 ! nr3c1-smarca4-1 physical interaction relationship: participates_in CCO:I0016289 ! arid1a-smarca4- physical interaction relationship: participates_in CCO:I0017250 ! relb-smarca4 physical interaction relationship: participates_in CCO:I0017376 ! pb1-arid2-5 physical interaction relationship: participates_in CCO:I0017881 ! smarca4-arid1a-1 physical interaction relationship: participates_in CCO:I0017882 ! arid1a-smarca4-5 physical interaction relationship: participates_in CCO:I0017884 ! smarca4-arid1b-1 physical interaction relationship: participates_in CCO:I0017885 ! arid1b-smarca4-1 physical interaction relationship: participates_in CCO:I0018067 ! arid1a-smarca4-3 physical interaction relationship: participates_in CCO:I0018327 ! arid1a-smarca4-4 physical interaction relationship: participates_in CCO:I0018329 ! arid1b-smarca4-5 physical interaction relationship: participates_in CCO:I0018533 ! smarca4-rest physical interaction relationship: participates_in CCO:I0018535 ! smarca4-rest-1 physical interaction relationship: participates_in CCO:I0018536 ! smarca4-rcor1 physical interaction relationship: participates_in CCO:I0018540 ! hdac1-smarca4 physical interaction relationship: participates_in CCO:I0019259 ! smarca4-arid2-1 physical interaction relationship: participates_in CCO:I0019476 ! pparg-brg1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000652 ! methylation-dependent chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0014098 ! SMCA4_HUMAN-Phosphothreonine11 relationship: transforms_into CCO:B0014099 ! SMCA4_HUMAN-Phosphoserine610 relationship: transforms_into CCO:B0014100 ! SMCA4_HUMAN-Phosphoserine655 relationship: transforms_into CCO:B0014101 ! SMCA4_HUMAN-Phosphoserine657 relationship: transforms_into CCO:B0014102 ! SMCA4_HUMAN-Phosphoserine660 relationship: transforms_into CCO:B0014103 ! SMCA4_HUMAN-Phosphoserine662 relationship: transforms_into CCO:B0014104 ! SMCA4_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0014105 ! SMCA4_HUMAN-Phosphoserine721 relationship: transforms_into CCO:B0014106 ! SMCA4_HUMAN-Phosphoserine1382 relationship: transforms_into CCO:B0014107 ! SMCA4_HUMAN-Phosphoserine1452 relationship: transforms_into CCO:B0070630 ! SMCA4_HUMAN-Phosphoserine613 relationship: transforms_into CCO:B0070631 ! SMCA4_HUMAN-Phosphoserine1570 relationship: transforms_into CCO:B0070632 ! SMCA4_HUMAN-Phosphoserine1575 relationship: transforms_into CCO:B0070633 ! SMCA4_HUMAN-Phosphoserine1586 relationship: transforms_into CCO:B0070634 ! SMCA4_HUMAN-Phosphoserine1627 relationship: transforms_into CCO:B0070635 ! SMCA4_HUMAN-Phosphoserine1631 relationship: transforms_into CCO:B0070636 ! SMCA4_HUMAN-Phosphoserine1640 relationship: transforms_into CCO:B0070637 ! SMCA4_HUMAN-Phosphoserine1642 relationship: transforms_into CCO:B0070638 ! SMCA4_HUMAN-Phosphoserine1644 [Term] id: CCO:B0005415 name: SMRD1_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1" [UniProtKB:Q96GM5] synonym: "60 kDa BRG-1/Brm-associated factor subunit A" EXACT [UniProtKB:Q96GM5] synonym: "BRG1-associated factor 60A" EXACT [UniProtKB:Q96GM5] synonym: "SWI/SNF complex 60 kDa subunit" EXACT [UniProtKB:Q96GM5] xref: EMBL:AAC50695.1 xref: EMBL:AAD23390.1 xref: EMBL:AAH09368.3 xref: UniProtKB:Q92924 xref: UniProtKB:Q96GM5 xref: UniProtKB:Q9Y635 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005638 ! SMARCD1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005052 ! protein complex scaffold relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000806 ! chromatin remodeling complex relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0006977 ! smarca4-pb1-arid2-2 physical interaction relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0014983 ! krt15-smarcd1 physical interaction relationship: participates_in CCO:I0015234 ! smarcd1-ushbp1 physical interaction relationship: participates_in CCO:I0015558 ! ndp52-smarcd1 physical interaction relationship: participates_in CCO:I0015627 ! ldoc1-smarcd1 physical interaction relationship: participates_in CCO:I0016891 ! relb-smarcd1 physical interaction relationship: participates_in CCO:I0018067 ! arid1a-smarca4-3 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002770 ! chromatin-mediated maintenance of transcription [Term] id: CCO:B0005416 name: SMCE1_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1" [UniProtKB:Q969G3] synonym: "BRG1-associated factor 57" EXACT [UniProtKB:Q969G3] xref: EMBL:AAC04509.1 xref: EMBL:AAH07082.1 xref: EMBL:AAH11017.1 xref: EMBL:AAH63700.1 xref: EMBL:AAP35840.1 xref: UniProtKB:O43539 xref: UniProtKB:Q969G3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005632 ! SMARCE1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0006938 ! brms1-smarce1 physical interaction relationship: participates_in CCO:I0006977 ! smarca4-pb1-arid2-2 physical interaction relationship: participates_in CCO:I0007259 ! arid2-pb1-1 physical interaction relationship: participates_in CCO:I0007356 ! pb1-arid2-3 physical interaction relationship: participates_in CCO:I0007722 ! smarce1-brms1 physical interaction relationship: participates_in CCO:I0017376 ! pb1-arid2-5 physical interaction relationship: participates_in CCO:I0017448 ! disc1-smarce1-1 physical interaction relationship: participates_in CCO:I0017819 ! disc1-smarce1 physical interaction relationship: participates_in CCO:I0018067 ! arid1a-smarca4-3 physical interaction relationship: participates_in CCO:I0018532 ! smarce1-rest physical interaction relationship: participates_in CCO:I0018539 ! hdac1-smarce1 physical interaction relationship: participates_in CCO:I0019260 ! smarce1-arid2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0005417 name: SMRC2_HUMAN def: "SWI/SNF complex subunit SMARCC2" [UniProtKB:Q8TAQ2] synonym: "BRG1-associated factor 170" EXACT [UniProtKB:Q8TAQ2] synonym: "SWI/SNF complex 170 kDa subunit" EXACT [UniProtKB:Q8TAQ2] synonym: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2" EXACT [UniProtKB:Q8TAQ2] xref: EMBL:AAC50694.1 xref: EMBL:AAH09067.1 xref: EMBL:AAH13045.1 xref: EMBL:AAH26222.1 xref: EMBL:AAP88926.1 xref: UniProtKB:Q8TAQ2 xref: UniProtKB:Q92923 xref: UniProtKB:Q96E12 xref: UniProtKB:Q96GY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005637 ! SMARCC2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0006977 ! smarca4-pb1-arid2-2 physical interaction relationship: participates_in CCO:I0007259 ! arid2-pb1-1 physical interaction relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0016744 ! map3k3-q8taq2 physical interaction relationship: participates_in CCO:I0017252 ! relb-q8taq2 physical interaction relationship: participates_in CCO:I0018067 ! arid1a-smarca4-3 physical interaction relationship: participates_in CCO:I0018534 ! smarcc2-rest physical interaction relationship: participates_in CCO:I0018537 ! smarcc2-rcor1 physical interaction relationship: participates_in CCO:I0018541 ! hdac1-smarcc2 physical interaction relationship: participates_in CCO:I0019106 ! atxn1-smarcc2 physical interaction relationship: participates_in CCO:I0019792 ! polr2c-smarcc2 physical interaction relationship: participates_in CCO:I0020103 ! pex14-smarcc2 physical interaction relationship: participates_in CCO:I0020240 ! arrb2-smarcc2 physical interaction relationship: participates_in CCO:I0020352 ! itsn1-smarcc2 physical interaction relationship: participates_in CCO:I0020403 ! phyhip-smarcc2 physical interaction relationship: participates_in CCO:I0020609 ! nova1-smarcc2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014120 ! SMRC2_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0014121 ! SMRC2_HUMAN-Phosphotyrosine296 relationship: transforms_into CCO:B0014122 ! SMRC2_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0014123 ! SMRC2_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0014124 ! SMRC2_HUMAN-Phosphothreonine322 relationship: transforms_into CCO:B0014125 ! SMRC2_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0036031 ! SMRC2_HUMAN-Phosphoserine806 relationship: transforms_into CCO:B0070649 ! SMRC2_HUMAN-Phosphoserine286 [Term] id: CCO:B0005418 name: SMRC1_HUMAN def: "SWI/SNF complex subunit SMARCC1" [UniProtKB:Q92922] synonym: "BRG1-associated factor 155" EXACT [UniProtKB:Q92922] synonym: "SWI/SNF complex 155 kDa subunit" EXACT [UniProtKB:Q92922] synonym: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1" EXACT [UniProtKB:Q92922] xref: EMBL:AAC50693.1 xref: EMBL:AAH39843.1 xref: EMBL:AAH65253.1 xref: EMBL:AAI13466.1 xref: EMBL:AAI17214.1 xref: UniProtKB:Q17RS0 xref: UniProtKB:Q6P172 xref: UniProtKB:Q8IWH2 xref: UniProtKB:Q92922 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005636 ! SMARCC1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0007259 ! arid2-pb1-1 physical interaction relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0016250 ! nr3c1-smarca4-2 physical interaction relationship: participates_in CCO:I0016456 ! ikbkb-baf155 physical interaction relationship: participates_in CCO:I0017251 ! relb-baf155 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014113 ! SMRC1_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0014114 ! SMRC1_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0014115 ! SMRC1_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0014116 ! SMRC1_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0014117 ! SMRC1_HUMAN-Phosphothreonine335 relationship: transforms_into CCO:B0014118 ! SMRC1_HUMAN-Phosphothreonine337 relationship: transforms_into CCO:B0014119 ! SMRC1_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0048396 ! SMRC1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0070648 ! SMRC1_HUMAN-Phosphoserine573 [Term] id: CCO:B0005419 name: SMRD2_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2" [UniProtKB:Q92925] synonym: "60 kDa BRG-1/Brm-associated factor subunit B" EXACT [UniProtKB:Q92925] synonym: "BRG1-associated factor 60B" EXACT [UniProtKB:Q92925] xref: EMBL:AAC50696.1 xref: EMBL:AAF20280.1 xref: EMBL:AAH18953.2 xref: UniProtKB:Q7L2I6 xref: UniProtKB:Q92925 xref: UniProtKB:Q9UHZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005639 ! SMARCD2_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006205 ! smarca4-pb1-arid2-1 physical interaction relationship: participates_in CCO:I0016877 ! relb-baf60b physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0014126 ! SMRD2_HUMAN-Phosphothreonine142 relationship: transforms_into CCO:B0014127 ! SMRD2_HUMAN-Phosphothreonine408 [Term] id: CCO:B0005420 name: BAK_HUMAN def: "Bcl-2 homologous antagonist/killer" [UniProtKB:Q16611] synonym: "Apoptosis regulator BAK" EXACT [UniProtKB:Q16611] synonym: "Bcl-2-like 7 protein" EXACT [UniProtKB:Q16611] xref: EMBL:AAA74466.1 xref: EMBL:AAA93066.1 xref: EMBL:AAH04431.1 xref: EMBL:AAO74828.1 xref: EMBL:BAA13606.1 xref: EMBL:CAA58997.1 xref: EMBL:CAB65626.1 xref: UniProtKB:Q16611 xref: UniProtKB:Q92533 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004135 ! BAK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006208 ! bcl2-bak-1 physical interaction relationship: participates_in CCO:I0007764 ! bak-bax-1 physical interaction relationship: participates_in CCO:I0015845 ! bak1-bcl2l1 physical interaction relationship: participates_in CCO:I0017808 ! bak1-mcl1 physical interaction relationship: participates_in CCO:I0017870 ! bid-bak1-1 direct interaction [Term] id: CCO:B0005421 name: BIK_HUMAN def: "Bcl-2-interacting killer" [UniProtKB:Q13323] synonym: "Apoptosis inducer NBK" EXACT [UniProtKB:Q13323] synonym: "BIP1" EXACT [UniProtKB:Q13323] synonym: "BP4" EXACT [UniProtKB:Q13323] xref: EMBL:AAC50413.1 xref: EMBL:AAC79124.1 xref: EMBL:AAF01156.1 xref: EMBL:AAH01599.1 xref: EMBL:AAO61089.1 xref: EMBL:AAP35374.1 xref: EMBL:CAA18260.2 xref: EMBL:CAA62013.1 xref: EMBL:CAG30276.1 xref: UniProtKB:Q13323 xref: UniProtKB:Q16582 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004161 ! BIK_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006210 ! bcl2-bik-1 physical interaction relationship: participates_in CCO:I0007935 ! bcl2-bik direct interaction relationship: participates_in CCO:I0015827 ! bcl2l1-bik physical interaction relationship: participates_in CCO:I0019273 ! bik-bclw-2 direct interaction relationship: participates_in CCO:I0019465 ! bcl2l1-bik-1 direct interaction relationship: participates_in CCO:I0019469 ! bcl2l2-bik direct interaction relationship: participates_in CCO:I0019472 ! mcl1-bik direct interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0005422 name: BID_HUMAN def: "BH3-interacting domain death agonist" [UniProtKB:P55957] synonym: "BID" EXACT [UniProtKB:P55957] synonym: "p22 BID" EXACT [UniProtKB:P55957] xref: EMBL:AAC34365.1 xref: EMBL:AAF89091.1 xref: EMBL:AAH09197.1 xref: EMBL:AAH22072.2 xref: EMBL:AAH33634.1 xref: EMBL:AAH36364.2 xref: EMBL:AAO32633.1 xref: EMBL:AAP50259.1 xref: EMBL:AAP97190.1 xref: EMBL:CAG28531.1 xref: EMBL:CAG30275.1 xref: UniProtKB:P55957 xref: UniProtKB:Q549M7 xref: UniProtKB:Q71T04 xref: UniProtKB:Q7Z4M9 xref: UniProtKB:Q8IY86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004160 ! BID_human relationship: has_function CCO:F0001425 ! death receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:I0006211 ! bcl2-bid-1 physical interaction relationship: participates_in CCO:I0006296 ! bid-bcl2-1 physical interaction relationship: participates_in CCO:I0007882 ! bid_bcl2_human direct interaction relationship: participates_in CCO:I0007933 ! bcl2-bid direct interaction relationship: participates_in CCO:I0017870 ! bid-bak1-1 direct interaction relationship: participates_in CCO:I0019275 ! bid-bclw-2 direct interaction relationship: participates_in CCO:I0019464 ! bcl2l2-bid direct interaction relationship: participates_in CCO:I0019468 ! bcl2l1-bid-1 direct interaction relationship: participates_in CCO:I0019471 ! mcl1-bid direct interaction relationship: participates_in CCO:I0019474 ! bcl2a1-bid direct interaction relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0000844 ! apoptotic mitochondrial changes relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0010792 ! BID_HUMAN-Phosphotyrosine54 relationship: transforms_into CCO:B0010793 ! BID_HUMAN-Phosphoserine78 [Term] id: CCO:B0005423 name: DNM3B_HUMAN def: "DNA (cytosine-5)-methyltransferase 3B" [UniProtKB:Q9UBC3] synonym: "DNA methyltransferase HsaIIIB" EXACT [UniProtKB:Q9UBC3] synonym: "DNA MTase HsaIIIB" EXACT [UniProtKB:Q9UBC3] synonym: "Dnmt3b" EXACT [UniProtKB:Q9UBC3] synonym: "EC 2.1.1.37" EXACT [UniProtKB:Q9UBC3] synonym: "M.HsaIIIB" EXACT [UniProtKB:Q9UBC3] xref: EMBL:AAD31432.1 xref: EMBL:AAD31433.1 xref: EMBL:AAD31434.1 xref: EMBL:AAD53062.1 xref: EMBL:AAD53063.1 xref: EMBL:AAF04015.1 xref: EMBL:AAL57040.1 xref: EMBL:CAB53069.1 xref: EMBL:CAB53070.1 xref: EMBL:CAB53071.1 xref: UniProtKB:Q9UBC3 xref: UniProtKB:Q9UBD4 xref: UniProtKB:Q9UJQ5 xref: UniProtKB:Q9UKA6 xref: UniProtKB:Q9UNE5 xref: UniProtKB:Q9Y5R9 xref: UniProtKB:Q9Y5S0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004495 ! DNMT3B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000405 ! DNA (cytosine-5-)-methyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002339 ! DNA-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006213 ! dnmt3b-ube2i-2 physical interaction relationship: participates_in CCO:I0006630 ! dnmt3b-ubl1-ube2i-1 physical interaction relationship: participates_in CCO:I0007287 ! dnmt3b-ube2i-1 physical interaction relationship: participates_in CCO:I0016139 ! dnmt3b-ubl1-2 physical interaction relationship: participates_in CCO:I0017522 ! ezh2-dnmt3b physical interaction relationship: participates_in CCO:I0017645 ! dnmt3b-ubl1-3 colocalization relationship: participates_in CCO:I0017734 ! dnm3b-ezh2 physical interaction relationship: participates_in CCO:I0018354 ! dnmt3b-ubl1-1 physical interaction relationship: participates_in CCO:I0019293 ! dnmt3b-ezh2 physical interaction relationship: participates_in CCO:I0019294 ! dnmt1-ezh2-1 physical interaction relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0005424 name: EP15_HUMAN def: "Epidermal growth factor receptor substrate 15" [UniProtKB:P42566] synonym: "AF-1p protein" EXACT [UniProtKB:P42566] synonym: "Protein Eps15" EXACT [UniProtKB:P42566] xref: EMBL:AAA52101.1 xref: EMBL:ABD34786.1 xref: EMBL:CAA82305.1 xref: EMBL:CAI13030.1 xref: UniProtKB:P42566 xref: UniProtKB:Q5SRH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004567 ! EPS15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006214 ! rabgef1-egfr physical interaction relationship: participates_in CCO:I0016337 ! eps15-hrb-1 physical interaction relationship: participates_in CCO:I0018145 ! rnf11-amsh-1 physical interaction relationship: participates_in CCO:I0018198 ! rnf11-ep15-1 physical interaction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011696 ! EP15_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0011697 ! EP15_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0011698 ! EP15_HUMAN-Phosphoserine485 relationship: transforms_into CCO:B0011699 ! EP15_HUMAN-Phosphoserine562 relationship: transforms_into CCO:B0011700 ! EP15_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0011701 ! EP15_HUMAN-Phosphothreonine779 relationship: transforms_into CCO:B0011702 ! EP15_HUMAN-Phosphoserine814 relationship: transforms_into CCO:B0011703 ! EP15_HUMAN-Phosphotyrosine849 relationship: transforms_into CCO:B0041135 ! EP15_HUMAN-Phosphothreonine777 relationship: transforms_into CCO:B0041136 ! EP15_HUMAN-Phosphoserine796 relationship: transforms_into CCO:B0065076 ! EP15_HUMAN-Phosphoserine140 [Term] id: CCO:B0005425 name: ATX1_HUMAN def: "Ataxin-1" [UniProtKB:P54253] synonym: "Spinocerebellar ataxia type 1 protein" EXACT [UniProtKB:P54253] xref: EMBL:AAD14401.1 xref: EMBL:AAI17126.1 xref: EMBL:CAA15622.1 xref: EMBL:CAA55793.1 xref: UniProtKB:P54253 xref: UniProtKB:Q17S02 xref: UniProtKB:Q9UJG2 xref: UniProtKB:Q9Y4J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004126 ! ATXN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006215 ! atxn1-ccnk physical interaction relationship: participates_in CCO:I0006645 ! ccnk-atxn1 physical interaction relationship: participates_in CCO:I0006646 ! cdk6-atxn1 physical interaction relationship: participates_in CCO:I0006647 ! pim2-atxn1 physical interaction relationship: participates_in CCO:I0007619 ! atxn1-btg3 physical interaction relationship: participates_in CCO:I0007620 ! atxn1-apbb1 physical interaction relationship: participates_in CCO:I0007621 ! atxn1-apbb1-1 physical interaction relationship: participates_in CCO:I0007622 ! atxn1-ube2i physical interaction relationship: participates_in CCO:I0007623 ! atxn1-btg3-1 physical interaction relationship: participates_in CCO:I0007624 ! atxn1-dctn3 physical interaction relationship: participates_in CCO:I0007625 ! atxn1-gspt1 physical interaction relationship: participates_in CCO:I0008785 ! atxn1-psmc3 physical interaction relationship: participates_in CCO:I0016162 ! atxn1-cpsf5 physical interaction relationship: participates_in CCO:I0016163 ! atxn1-crk physical interaction relationship: participates_in CCO:I0016164 ! atxn1-dazap2 physical interaction relationship: participates_in CCO:I0016165 ! atxn1-flj12529 physical interaction relationship: participates_in CCO:I0016166 ! atxn1-kiaa0174 physical interaction relationship: participates_in CCO:I0016167 ! atxn1-klhl12 physical interaction relationship: participates_in CCO:I0016168 ! atxn1-c1orf94 physical interaction relationship: participates_in CCO:I0016169 ! atxn1-plekha5 physical interaction relationship: participates_in CCO:I0016170 ! atxn1-rbm9 physical interaction relationship: participates_in CCO:I0016171 ! atxn1-rbpms physical interaction relationship: participates_in CCO:I0016172 ! atxn1-tbc1d5 physical interaction relationship: participates_in CCO:I0016173 ! atxn1-traf2 physical interaction relationship: participates_in CCO:I0016174 ! atxn1-trim32 physical interaction relationship: participates_in CCO:I0016175 ! atxn1-u2af2 physical interaction relationship: participates_in CCO:I0016177 ! a2bp1-atxn1 physical interaction relationship: participates_in CCO:I0016179 ! atxn1-bat2 physical interaction relationship: participates_in CCO:I0016180 ! atxn1-cfl1 physical interaction relationship: participates_in CCO:I0016181 ! atxn1-hivep1 physical interaction relationship: participates_in CCO:I0016182 ! atxn1-yy1ap1 physical interaction relationship: participates_in CCO:I0016183 ! atxn1-zhx1 physical interaction relationship: participates_in CCO:I0016184 ! atxn1-atxn2 physical interaction relationship: participates_in CCO:I0016185 ! atxn1-six5 physical interaction relationship: participates_in CCO:I0016186 ! atxn1-derp6 physical interaction relationship: participates_in CCO:I0016189 ! atxn1-rbpms-2 physical interaction relationship: participates_in CCO:I0016190 ! atxn1-rbpms-3 physical interaction relationship: participates_in CCO:I0017553 ! atp6v0d1-atxn1 physical interaction relationship: participates_in CCO:I0017554 ! cpsf5-atxn1 physical interaction relationship: participates_in CCO:I0017555 ! crk-atxn1 physical interaction relationship: participates_in CCO:I0017556 ! cxorf20-atxn1 physical interaction relationship: participates_in CCO:I0017557 ! efemp2-atxn1 physical interaction relationship: participates_in CCO:I0017558 ! fam46a-atxn1 physical interaction relationship: participates_in CCO:I0017559 ! fam46b-atxn1 physical interaction relationship: participates_in CCO:I0017560 ! zc3h10-atxn1 physical interaction relationship: participates_in CCO:I0017561 ! q9h7h0-atxn1 physical interaction relationship: participates_in CCO:I0017562 ! kiaa0174-atxn1 physical interaction relationship: participates_in CCO:I0017563 ! numbl-atxn1 physical interaction relationship: participates_in CCO:I0017564 ! pcqap-atxn1 physical interaction relationship: participates_in CCO:I0017565 ! sfrs16-atxn1 physical interaction relationship: participates_in CCO:I0017566 ! tcap-atxn1 physical interaction relationship: participates_in CCO:I0017567 ! fazf-atxn1 physical interaction relationship: participates_in CCO:I0017568 ! u2af2-atxn1 physical interaction relationship: participates_in CCO:I0017569 ! zcchc13-atxn1 physical interaction relationship: participates_in CCO:I0017602 ! atxn1-dazap2-1 physical interaction relationship: participates_in CCO:I0017603 ! atxn1-klhl12-1 physical interaction relationship: participates_in CCO:I0017604 ! atxn1-otx2 physical interaction relationship: participates_in CCO:I0017605 ! atxn1-plekha5-1 physical interaction relationship: participates_in CCO:I0017606 ! atxn1-rbm9-5 physical interaction relationship: participates_in CCO:I0017607 ! atxn1-rbpms-1 physical interaction relationship: participates_in CCO:I0017608 ! atxn1-tbc1d5-1 physical interaction relationship: participates_in CCO:I0017609 ! atxn1-traf2-1 physical interaction relationship: participates_in CCO:I0017610 ! atxn1-trim32-1 physical interaction relationship: participates_in CCO:I0017611 ! atxn1-u2af2-2 physical interaction relationship: participates_in CCO:I0017626 ! q8n8b7-atxn1 physical interaction relationship: participates_in CCO:I0017627 ! c1orf94-atxn1 physical interaction relationship: participates_in CCO:I0017628 ! atxn1-q86uw1-1 physical interaction relationship: participates_in CCO:I0017629 ! atxn1-flj12529-1 physical interaction relationship: participates_in CCO:I0017630 ! atxn1-c1orf94-1 physical interaction relationship: participates_in CCO:I0018371 ! atxn1-ubqln4-1 colocalization relationship: participates_in CCO:I0018634 ! atxn1-ubqln4 physical interaction relationship: participates_in CCO:I0018635 ! atxn1-ubqln4-2 physical interaction relationship: participates_in CCO:I0018636 ! atxn1-atxn1 physical interaction relationship: participates_in CCO:I0018904 ! a2bp1-atxn1-1 physical interaction relationship: participates_in CCO:I0018941 ! atxn1-ubqln4-3 physical interaction relationship: participates_in CCO:I0018942 ! atxn1-acaca physical interaction relationship: participates_in CCO:I0018943 ! atxn1-atp1a3 physical interaction relationship: participates_in CCO:I0018944 ! atxn1-bat2-1 physical interaction relationship: participates_in CCO:I0018945 ! atxn1-c20orf102 physical interaction relationship: participates_in CCO:I0018946 ! atxn1-c2orf10 physical interaction relationship: participates_in CCO:I0018947 ! atxn1-cfl1-1 physical interaction relationship: participates_in CCO:I0018948 ! atxn1-cic physical interaction relationship: participates_in CCO:I0018949 ! atxn1-clec4f physical interaction relationship: participates_in CCO:I0018950 ! atxn1-coil physical interaction relationship: participates_in CCO:I0018951 ! atxn1-fdps physical interaction relationship: participates_in CCO:I0018952 ! atxn1-q9h7h0 physical interaction relationship: participates_in CCO:I0018953 ! atxn1-hivep1-1 physical interaction relationship: participates_in CCO:I0018954 ! atxn1-kiaa0553 physical interaction relationship: participates_in CCO:I0018955 ! atxn1-klf11 physical interaction relationship: participates_in CCO:I0018956 ! atxn1-lw_1 physical interaction relationship: participates_in CCO:I0018957 ! atxn1-rbm9-1 physical interaction relationship: participates_in CCO:I0018958 ! atxn1-rcn1 physical interaction relationship: participates_in CCO:I0018959 ! atxn1-rnf31 physical interaction relationship: participates_in CCO:I0018960 ! atxn1-yy1ap1-1 physical interaction relationship: participates_in CCO:I0018961 ! atxn1-zhx1-1 physical interaction relationship: participates_in CCO:I0018962 ! atxn1-znf488 physical interaction relationship: participates_in CCO:I0018963 ! atxn1-ubqln4-4 physical interaction relationship: participates_in CCO:I0018964 ! atxn1-atp1a3-1 physical interaction relationship: participates_in CCO:I0018965 ! atxn1-atxn1-1 physical interaction relationship: participates_in CCO:I0018966 ! atxn1-c20orf102-1 physical interaction relationship: participates_in CCO:I0018967 ! atxn1-cfl1-2 physical interaction relationship: participates_in CCO:I0018968 ! atxn1-cic-1 physical interaction relationship: participates_in CCO:I0018969 ! atxn1-coil-1 physical interaction relationship: participates_in CCO:I0018970 ! atxn1-dmpk physical interaction relationship: participates_in CCO:I0018971 ! atxn1-q96d80 physical interaction relationship: participates_in CCO:I0018972 ! atxn1-q9h7h0-1 physical interaction relationship: participates_in CCO:I0018973 ! atxn1-gmeb2 physical interaction relationship: participates_in CCO:I0018974 ! atxn1-hivep1-2 physical interaction relationship: participates_in CCO:I0018975 ! atxn1-ipo8 physical interaction relationship: participates_in CCO:I0018976 ! atxn1-kiaa0553-1 physical interaction relationship: participates_in CCO:I0018977 ! atxn1-mbp physical interaction relationship: participates_in CCO:I0018978 ! atxn1-phpt1 physical interaction relationship: participates_in CCO:I0018979 ! atxn1-rbm9-2 physical interaction relationship: participates_in CCO:I0018980 ! atxn1-rcn1-1 physical interaction relationship: participates_in CCO:I0018981 ! atxn1-six5-1 physical interaction relationship: participates_in CCO:I0018982 ! atxn1-srebf1 physical interaction relationship: participates_in CCO:I0018983 ! atxn1-tmem23 physical interaction relationship: participates_in CCO:I0018984 ! atxn1-ttc19 physical interaction relationship: participates_in CCO:I0018985 ! atxn1-yy1ap1-2 physical interaction relationship: participates_in CCO:I0018986 ! atxn1-zhx1-2 physical interaction relationship: participates_in CCO:I0018987 ! atxn1-znf488-1 physical interaction relationship: participates_in CCO:I0018988 ! atxn1-atxn2-1 physical interaction relationship: participates_in CCO:I0018989 ! atxn1-atxn2l physical interaction relationship: participates_in CCO:I0018990 ! atxn1-bat2-2 physical interaction relationship: participates_in CCO:I0018991 ! atxn1-cic-2 physical interaction relationship: participates_in CCO:I0018992 ! atxn1-zc3h10 physical interaction relationship: participates_in CCO:I0018993 ! atxn1-fyn physical interaction relationship: participates_in CCO:I0018994 ! atxn1-hivep1-3 physical interaction relationship: participates_in CCO:I0018995 ! atxn1-hpcal1 physical interaction relationship: participates_in CCO:I0018996 ! atxn1-hsn2 physical interaction relationship: participates_in CCO:I0018997 ! atxn1-kiaa0553-2 physical interaction relationship: participates_in CCO:I0018998 ! atxn1-kiaa0685 physical interaction relationship: participates_in CCO:I0018999 ! atxn1-r3hdm2 physical interaction relationship: participates_in CCO:I0019000 ! atxn1-klf11-1 physical interaction relationship: participates_in CCO:I0019001 ! atxn1-lw_1-1 physical interaction relationship: participates_in CCO:I0019002 ! atxn1-mterfd2 physical interaction relationship: participates_in CCO:I0019003 ! atxn1-oaz1 physical interaction relationship: participates_in CCO:I0019004 ! atxn1-pum1 physical interaction relationship: participates_in CCO:I0019005 ! atxn1-rapgef4 physical interaction relationship: participates_in CCO:I0019006 ! atxn1-rbm9-3 physical interaction relationship: participates_in CCO:I0019007 ! atxn1-rics physical interaction relationship: participates_in CCO:I0019008 ! atxn1-six5-2 physical interaction relationship: participates_in CCO:I0019009 ! atxn1-spen physical interaction relationship: participates_in CCO:I0019010 ! atxn1-kiaa0809 physical interaction relationship: participates_in CCO:I0019011 ! atxn1-ube2e3 physical interaction relationship: participates_in CCO:I0019012 ! atxn1-wnk2 physical interaction relationship: participates_in CCO:I0019013 ! atxn1-zfp276 physical interaction relationship: participates_in CCO:I0019014 ! atxn1-zhx1-3 physical interaction relationship: participates_in CCO:I0019015 ! atxn1-zhx2 physical interaction relationship: participates_in CCO:I0019016 ! atxn1-zhx3 physical interaction relationship: participates_in CCO:I0019017 ! atxn1-arid5a physical interaction relationship: participates_in CCO:I0019018 ! atxn1-atxn1-2 physical interaction relationship: participates_in CCO:I0019019 ! atxn1-atxn2-2 physical interaction relationship: participates_in CCO:I0019020 ! atxn1-atxn2l-1 physical interaction relationship: participates_in CCO:I0019021 ! atxn1-bat2-3 physical interaction relationship: participates_in CCO:I0019022 ! atxn1-c14orf92 physical interaction relationship: participates_in CCO:I0019023 ! atxn1-c20orf102-2 physical interaction relationship: participates_in CCO:I0019024 ! atxn1-c2orf10-1 physical interaction relationship: participates_in CCO:I0019025 ! atxn1-cic-3 physical interaction relationship: participates_in CCO:I0019026 ! atxn1-cst3 physical interaction relationship: participates_in CCO:I0019027 ! atxn1-dmpk-1 physical interaction relationship: participates_in CCO:I0019028 ! atxn1-dnaja3 physical interaction relationship: participates_in CCO:I0019029 ! atxn1-dzip3 physical interaction relationship: participates_in CCO:I0019030 ! atxn1-efemp2 physical interaction relationship: participates_in CCO:I0019031 ! atxn1-eif1ay physical interaction relationship: participates_in CCO:I0019032 ! atxn1-eif4enif1 physical interaction relationship: participates_in CCO:I0019033 ! atxn1-entpd6 physical interaction relationship: participates_in CCO:I0019034 ! atxn1-fam48a physical interaction relationship: participates_in CCO:I0019035 ! atxn1-fhl2 physical interaction relationship: participates_in CCO:I0019036 ! atxn1-zc3h10-1 physical interaction relationship: participates_in CCO:I0019037 ! atxn1-q9nxg9 physical interaction relationship: participates_in CCO:I0019038 ! atxn1-fyn-1 physical interaction relationship: participates_in CCO:I0019039 ! atxn1-g2 physical interaction relationship: participates_in CCO:I0019040 ! atxn1-gca physical interaction relationship: participates_in CCO:I0019041 ! atxn1-hivep1-4 physical interaction relationship: participates_in CCO:I0019042 ! atxn1-hspa1a physical interaction relationship: participates_in CCO:I0019043 ! atxn1-itgb4 physical interaction relationship: participates_in CCO:I0019044 ! atxn1-kcnab2 physical interaction relationship: participates_in CCO:I0019045 ! atxn1-kiaa0553-3 physical interaction relationship: participates_in CCO:I0019046 ! atxn1-kiaa0685-1 physical interaction relationship: participates_in CCO:I0019047 ! atxn1-r3hdm2-1 physical interaction relationship: participates_in CCO:I0019048 ! atxn1-lw_1-2 physical interaction relationship: participates_in CCO:I0019049 ! atxn1-mll4 physical interaction relationship: participates_in CCO:I0019050 ! atxn1-myst3 physical interaction relationship: participates_in CCO:I0019051 ! atxn1-ncor1 physical interaction relationship: participates_in CCO:I0019052 ! atxn1-nlk physical interaction relationship: participates_in CCO:I0019053 ! atxn1-nr4a1 physical interaction relationship: participates_in CCO:I0019054 ! atxn1-pepd physical interaction relationship: participates_in CCO:I0019055 ! atxn1-prdm1 physical interaction relationship: participates_in CCO:I0019056 ! atxn1-r3hdm physical interaction relationship: participates_in CCO:I0019057 ! atxn1-rbm9-4 physical interaction relationship: participates_in CCO:I0019058 ! atxn1-rics-1 physical interaction relationship: participates_in CCO:I0019059 ! atxn1-six5-3 physical interaction relationship: participates_in CCO:I0019060 ! atxn1-spen-1 physical interaction relationship: participates_in CCO:I0019061 ! atxn1-srebf1-1 physical interaction relationship: participates_in CCO:I0019062 ! atxn1-kiaa0809-1 physical interaction relationship: participates_in CCO:I0019063 ! atxn1-stac2 physical interaction relationship: participates_in CCO:I0019064 ! atxn1-tollip physical interaction relationship: participates_in CCO:I0019065 ! atxn1-trip6 physical interaction relationship: participates_in CCO:I0019066 ! atxn1-ubap2l physical interaction relationship: participates_in CCO:I0019067 ! atxn1-vsnl1 physical interaction relationship: participates_in CCO:I0019068 ! atxn1-yy1ap1-3 physical interaction relationship: participates_in CCO:I0019069 ! atxn1-zhx1-4 physical interaction relationship: participates_in CCO:I0019070 ! atxn1-zhx3-1 physical interaction relationship: participates_in CCO:I0019071 ! atxn1-zyx physical interaction relationship: participates_in CCO:I0019072 ! atxn1-cfl1-3 physical interaction relationship: participates_in CCO:I0019073 ! atxn1-cirbp physical interaction relationship: participates_in CCO:I0019074 ! atxn1-rp1_159a19_1 physical interaction relationship: participates_in CCO:I0019075 ! atxn1-q96d80-1 physical interaction relationship: participates_in CCO:I0019076 ! atxn1-q9h7h0-2 physical interaction relationship: participates_in CCO:I0019077 ! atxn1-gmeb2-1 physical interaction relationship: participates_in CCO:I0019078 ! atxn1-ipo8-1 physical interaction relationship: participates_in CCO:I0019079 ! atxn1-ptgds physical interaction relationship: participates_in CCO:I0019080 ! atxn1-rcn1-2 physical interaction relationship: participates_in CCO:I0019081 ! atxn1-zc3h7b physical interaction relationship: participates_in CCO:I0019082 ! atxn1-znf609 physical interaction relationship: participates_in CCO:I0019083 ! atxn1-ubqln4-5 physical interaction relationship: participates_in CCO:I0019084 ! atxn1-adcy6 physical interaction relationship: participates_in CCO:I0019085 ! atxn1-acot7 physical interaction relationship: participates_in CCO:I0019086 ! atxn1-cfl1-4 physical interaction relationship: participates_in CCO:I0019087 ! atxn1-clec4f-1 physical interaction relationship: participates_in CCO:I0019088 ! atxn1-coil-2 physical interaction relationship: participates_in CCO:I0019089 ! atxn1-derp6-1 physical interaction relationship: participates_in CCO:I0019090 ! atxn1-rp1_159a19_1-1 physical interaction relationship: participates_in CCO:I0019091 ! atxn1-fam21c physical interaction relationship: participates_in CCO:I0019092 ! atxn1-flj10404 physical interaction relationship: participates_in CCO:I0019093 ! atxn1-q96d80-2 physical interaction relationship: participates_in CCO:I0019094 ! atxn1-q9h7h0-3 physical interaction relationship: participates_in CCO:I0019095 ! atxn1-klhl8 physical interaction relationship: participates_in CCO:I0019096 ! atxn1-ldb1 physical interaction relationship: participates_in CCO:I0019097 ! atxn1-lrsam1 physical interaction relationship: participates_in CCO:I0019098 ! atxn1-matn2 physical interaction relationship: participates_in CCO:I0019099 ! atxn1-myo18a physical interaction relationship: participates_in CCO:I0019100 ! atxn1-nars physical interaction relationship: participates_in CCO:I0019101 ! atxn1-phpt1-1 physical interaction relationship: participates_in CCO:I0019102 ! atxn1-ptgds-1 physical interaction relationship: participates_in CCO:I0019103 ! atxn1-sara1 physical interaction relationship: participates_in CCO:I0019104 ! atxn1-sc4mol physical interaction relationship: participates_in CCO:I0019105 ! atxn1-sfrs14 physical interaction relationship: participates_in CCO:I0019106 ! atxn1-smarcc2 physical interaction relationship: participates_in CCO:I0019107 ! atxn1-st6galnac6 physical interaction relationship: participates_in CCO:I0019108 ! atxn1-u2af2-1 physical interaction relationship: participates_in CCO:I0019109 ! atxn1-zc3h5 physical interaction relationship: participates_in CCO:I0019110 ! atxn1-znf488-2 physical interaction relationship: participates_in CCO:I0019129 ! cic-atxn1 physical interaction relationship: participates_in CCO:I0019191 ! htatip-atxn1 physical interaction relationship: participates_in CCO:I0019192 ! atxn1-htatip-1 physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0063661 ! ATX1_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0063662 ! ATX1_HUMAN-Phosphoserine253 [Term] id: CCO:B0005426 name: CENPJ_HUMAN def: "Centromere protein J" [UniProtKB:Q9HC77] synonym: "CENP-J" EXACT [UniProtKB:Q9HC77] synonym: "Centrosomal P4.1-associated protein" EXACT [UniProtKB:Q9HC77] synonym: "LAG-3-associated protein" EXACT [UniProtKB:Q9HC77] synonym: "LYST-interacting protein 1" EXACT [UniProtKB:Q9HC77] xref: EMBL:AAG21074.1 xref: EMBL:AAG49440.1 xref: EMBL:AAH24209.3 xref: EMBL:AAI13111.1 xref: EMBL:AAI13663.1 xref: EMBL:AAI13665.1 xref: EMBL:CAC80028.1 xref: EMBL:CAI16635.1 xref: UniProtKB:Q2KHM6 xref: UniProtKB:Q5T6R5 xref: UniProtKB:Q96KS5 xref: UniProtKB:Q9C067 xref: UniProtKB:Q9HC77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004327 ! CENPJ_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000537 ! gamma-tubulin small complex relationship: participates_in CCO:I0006216 ! cenpj-gfi1b physical interaction relationship: participates_in CCO:I0007637 ! gfi1b-cenpj physical interaction relationship: participates_in CCO:I0016187 ! cenpj-cic physical interaction relationship: participates_in CCO:I0018921 ! atn1-cenpj physical interaction relationship: participates_in CCO:I0019130 ! cic-cenpj physical interaction relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0011176 ! CENPJ_HUMAN-Phosphoserine1109 [Term] id: CCO:B0005427 name: NELL2_HUMAN def: "Protein kinase C-binding protein NELL2 precursor" [UniProtKB:Q99435] synonym: "NEL-like protein 2" EXACT [UniProtKB:Q99435] synonym: "Nel-related protein 2" EXACT [UniProtKB:Q99435] xref: EMBL:AAH20544.1 xref: EMBL:BAA11681.1 xref: UniProtKB:Q99435 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005182 ! NELL2_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0006218 ! gfi1b-nell2 physical interaction relationship: participates_in CCO:I0007665 ! gfi1b-nell2-1 physical interaction [Term] id: CCO:B0005428 name: CSK21_HUMAN def: "Casein kinase II subunit alpha" [UniProtKB:P68400] synonym: "CK II" EXACT [UniProtKB:P68400] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P68400] xref: EMBL:AAA35503.1 xref: EMBL:AAA56821.1 xref: EMBL:AAH11668.1 xref: EMBL:AAH53532.1 xref: EMBL:AAH71167.1 xref: EMBL:CAA49758.1 xref: EMBL:CAB65624.1 xref: UniProtKB:P19138 xref: UniProtKB:P20426 xref: UniProtKB:P68400 xref: UniProtKB:Q14013 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004402 ! CSNK2A1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001052 ! protein kinase CK2 activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0006220 ! csnk2a1-pml-1 phosphorylation relationship: participates_in CCO:I0007379 ! csnk2a1-pml phosphorylation relationship: participates_in CCO:I0015937 ! csnk2a1-was-1 phosphorylation relationship: participates_in CCO:I0015938 ! csnk2a1-was-2 phosphorylation relationship: participates_in CCO:I0018116 ! csnk2a1-csnk2b-1 direct interaction relationship: participates_in CCO:I0018456 ! csnk2b-csnk2a1 physical interaction relationship: participates_in CCO:I0019700 ! csnk2a1-zhx1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0005429 name: UBP7_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 7" [UniProtKB:Q93009] synonym: "Deubiquitinating enzyme 7" EXACT [UniProtKB:Q93009] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q93009] synonym: "Herpesvirus-associated ubiquitin-specific protease" EXACT [UniProtKB:Q93009] synonym: "Ubiquitin thioesterase 7" EXACT [UniProtKB:Q93009] synonym: "Ubiquitin-specific-processing protease 7" EXACT [UniProtKB:Q93009] xref: EMBL:CAA96580.1 xref: EMBL:EAW85194.1 xref: UniProtKB:A6NMY8 xref: UniProtKB:Q93009 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005871 ! USP7_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006222 ! ubp7-daxx physical interaction relationship: participates_in CCO:I0006350 ! ubp7-daxx-2 colocalization relationship: participates_in CCO:I0006351 ! ubp7-daxx-3 direct interaction relationship: participates_in CCO:I0006559 ! ubp7-daxx-1 physical interaction relationship: participates_in CCO:I0006560 ! ubp7-daxx-5 physical interaction relationship: participates_in CCO:I0006763 ! usp7-tp53-5 physical interaction relationship: participates_in CCO:I0006902 ! ubp7-daxx-4 physical interaction relationship: participates_in CCO:I0007381 ! ubp7-daxx-6 physical interaction relationship: participates_in CCO:I0007384 ! usp7-tp53 physical interaction relationship: participates_in CCO:I0007385 ! usp7-tp53-1 physical interaction relationship: participates_in CCO:I0007386 ! usp7-tp53-2 physical interaction relationship: participates_in CCO:I0007387 ! usp7-mdm2 physical interaction relationship: participates_in CCO:I0007388 ! usp7-mdm2-1 physical interaction relationship: participates_in CCO:I0007389 ! usp7-mdm2-2 physical interaction relationship: participates_in CCO:I0007461 ! usp7-tp53-3 direct interaction relationship: participates_in CCO:I0007462 ! usp7-mdm2-5 direct interaction relationship: participates_in CCO:I0007808 ! ubp7-daxx-7 physical interaction relationship: participates_in CCO:I0007810 ! ubp7-daxx-9 physical interaction relationship: participates_in CCO:I0007812 ! usp7-hausp physical interaction relationship: participates_in CCO:I0007815 ! usp7-mdm2-4 direct interaction relationship: participates_in CCO:I0007928 ! daxx-usp7 physical interaction relationship: participates_in CCO:I0007930 ! usp7-mdm2-3 direct interaction relationship: participates_in CCO:I0007931 ! usp7-tp53-4 physical interaction relationship: participates_in CCO:I0007971 ! ubp7-daxx-10 physical interaction relationship: participates_in CCO:I0016856 ! relb-usp7 physical interaction relationship: participates_in CCO:I0017593 ! trim22-usp7 physical interaction relationship: participates_in CCO:I0019174 ! usp7-arnt2 physical interaction relationship: participates_in CCO:I0019175 ! usp7-dnaja3 physical interaction relationship: participates_in CCO:I0019176 ! usp7-ewsr1 physical interaction relationship: participates_in CCO:I0019177 ! usp7-prkcabp physical interaction relationship: participates_in CCO:I0019178 ! usp7-tmpo physical interaction relationship: participates_in CCO:I0019179 ! usp7-bcor physical interaction relationship: transforms_into CCO:B0014570 ! UBP7_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0071699 ! UBP7_HUMAN-Phosphoserine963 [Term] id: CCO:B0005430 name: HIF1A_HUMAN def: "Hypoxia-inducible factor 1 alpha" [UniProtKB:Q16665] synonym: "ARNT-interacting protein" EXACT [UniProtKB:Q16665] synonym: "Basic-helix-loop-helix-PAS protein MOP1" EXACT [UniProtKB:Q16665] synonym: "HIF-1 alpha" EXACT [UniProtKB:Q16665] synonym: "HIF1 alpha" EXACT [UniProtKB:Q16665] synonym: "Member of PAS protein 1" EXACT [UniProtKB:Q16665] xref: EMBL:AAC50152.1 xref: EMBL:AAC51210.1 xref: EMBL:AAC68568.1 xref: EMBL:AAF20139.1 xref: EMBL:AAF20140.1 xref: EMBL:AAF20149.1 xref: EMBL:AAG43026.1 xref: EMBL:AAH12527.1 xref: EMBL:AAP88778.1 xref: EMBL:BAB70608.1 xref: UniProtKB:Q16665 xref: UniProtKB:Q53XP6 xref: UniProtKB:Q96PT9 xref: UniProtKB:Q9UPB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004806 ! HIF1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006223 ! pcaf-hif1a physical interaction relationship: participates_in CCO:I0006352 ! pcaf-hif1a-1 physical interaction relationship: participates_in CCO:I0006702 ! hif1a-ep300-3 physical interaction relationship: participates_in CCO:I0006820 ! hif1a-vhl-1 physical interaction relationship: participates_in CCO:I0007175 ! hif1a-os9-4 direct interaction relationship: participates_in CCO:I0007176 ! hif1a-vhl physical interaction relationship: participates_in CCO:I0007529 ! hif1a-ep300-2 physical interaction relationship: participates_in CCO:I0007954 ! hif1a-ep300-1 physical interaction relationship: participates_in CCO:I0015185 ! hif1a-ssx4 physical interaction relationship: participates_in CCO:I0017967 ! os9-egln1-1 physical interaction relationship: participates_in CCO:I0017968 ! os9-hif1a physical interaction relationship: participates_in CCO:I0017969 ! os9-egln1-2 physical interaction relationship: participates_in CCO:I0017970 ! os9-egln1-3 physical interaction relationship: participates_in CCO:I0018125 ! hif1a-os9 physical interaction relationship: participates_in CCO:I0018265 ! hif1a-os9-1 direct interaction relationship: participates_in CCO:I0018266 ! os9-egln3-1 physical interaction relationship: participates_in CCO:I0018267 ! hif1a-os9-5 direct interaction relationship: participates_in CCO:I0018400 ! hif1a-hif1an-1 direct interaction relationship: participates_in CCO:I0018401 ! hif1a-hif1an-2 direct interaction relationship: participates_in CCO:I0018402 ! hif1a-hif1an-3 direct interaction relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0001356 ! positive regulation of vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002250 ! regulation of transcription from RNA polymerase II promoter in response to oxidative stress relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002462 ! positive regulation of erythrocyte differentiation relationship: participates_in CCO:P0002569 ! positive regulation of glycolysis relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002746 ! positive regulation of hormone biosynthetic process relationship: transforms_into CCO:B0012191 ! HIF1A_HUMAN-4-hydroxyproline402 relationship: transforms_into CCO:B0012193 ! HIF1A_HUMAN-4-hydroxyproline564 relationship: transforms_into CCO:B0012194 ! HIF1A_HUMAN-S-nitrosocysteine800 relationship: transforms_into CCO:B0012195 ! HIF1A_HUMAN-3-hydroxyasparagine803 [Term] id: CCO:B0005431 name: CENPB_HUMAN def: "Major centromere autoantigen B" [UniProtKB:P07199] synonym: "CENP-B" EXACT [UniProtKB:P07199] synonym: "Centromere protein B" EXACT [UniProtKB:P07199] xref: EMBL:AAH53847.1 xref: EMBL:CAA28918.1 xref: EMBL:CAA38879.1 xref: EMBL:CAC17547.1 xref: UniProtKB:P07199 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004322 ! CENPB_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000287 ! satellite DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0006225 ! cdca1_cenpb_1 colocalization relationship: participates_in CCO:I0006226 ! kntc2_cenpb_1 colocalization relationship: participates_in CCO:I0007636 ! gfi1b-cenpb physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0011135 ! CENPB_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0011136 ! CENPB_HUMAN-Phosphoserine165 [Term] id: CCO:B0005432 name: DCP1A_HUMAN def: "mRNA-decapping enzyme 1A" [UniProtKB:Q9NPI6] synonym: "EC 3.-.-.-" EXACT [UniProtKB:Q9NPI6] synonym: "Smad4-interacting transcriptional co-activator" EXACT [UniProtKB:Q9NPI6] synonym: "Transcription factor SMIF" EXACT [UniProtKB:Q9NPI6] xref: EMBL:AAH07439.1 xref: EMBL:AAN62763.1 xref: EMBL:BAA92008.1 xref: EMBL:CAB77023.1 xref: UniProtKB:Q9NPI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004444 ! DCP1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006228 ! rent1-dcp2 physical interaction relationship: participates_in CCO:I0006229 ! dcp1a-upf1 physical interaction relationship: participates_in CCO:I0006231 ! upf1-dcp1a-2 physical interaction relationship: participates_in CCO:I0006239 ! upf1-dcp1a-3 physical interaction relationship: participates_in CCO:I0006240 ! upf1-dcp1a-4 physical interaction relationship: participates_in CCO:I0006241 ! upf1-dcp1a-5 physical interaction relationship: participates_in CCO:I0006911 ! dcp1a-rcd8-xrn1 colocalization relationship: participates_in CCO:I0007014 ! upf1-dcp1a physical interaction relationship: participates_in CCO:I0007016 ! upf1-rcd8 physical interaction relationship: participates_in CCO:I0018109 ! zfp36-dcp1a physical interaction relationship: participates_in CCO:I0018111 ! zfp36-rcd8-1 physical interaction relationship: transforms_into CCO:B0011442 ! DCP1A_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0011443 ! DCP1A_HUMAN-Phosphoserine523 relationship: transforms_into CCO:B0011444 ! DCP1A_HUMAN-Phosphoserine525 relationship: transforms_into CCO:B0048221 ! DCP1A_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0048222 ! DCP1A_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0048223 ! DCP1A_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0048224 ! DCP1A_HUMAN-Phosphothreonine531 relationship: transforms_into CCO:B0064661 ! DCP1A_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0064662 ! DCP1A_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0064663 ! DCP1A_HUMAN-Phosphoserine522 [Term] id: CCO:B0005433 name: DCP2_HUMAN def: "mRNA-decapping enzyme 2" [UniProtKB:Q8IU60] synonym: "EC 3.-.-.-" EXACT [UniProtKB:Q8IU60] synonym: "hDpc" EXACT [UniProtKB:Q8IU60] synonym: "Nucleoside diphosphate-linked moiety X motif 20" EXACT [UniProtKB:Q8IU60] synonym: "Nudix motif 20" EXACT [UniProtKB:Q8IU60] xref: EMBL:AAH45596.1 xref: EMBL:AAH64593.1 xref: EMBL:AAN08884.1 xref: EMBL:AAN62762.1 xref: EMBL:BAC03479.1 xref: UniProtKB:Q6P2D4 xref: UniProtKB:Q7Z5W5 xref: UniProtKB:Q8IU60 xref: UniProtKB:Q8NBG5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004445 ! DCP2_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006228 ! rent1-dcp2 physical interaction relationship: participates_in CCO:I0006230 ! dcp2-upf physical interaction relationship: participates_in CCO:I0007015 ! upf1-dcp2 physical interaction relationship: transforms_into CCO:B0011445 ! DCP2_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0011446 ! DCP2_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0011447 ! DCP2_HUMAN-Phosphoserine249 relationship: transforms_into CCO:B0011448 ! DCP2_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0011449 ! DCP2_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0011450 ! DCP2_HUMAN-Phosphoserine347 [Term] id: CCO:B0005434 name: REN3B_HUMAN def: "Regulator of nonsense transcripts 3B" [UniProtKB:Q9BZI7] synonym: "hUpf3B" EXACT [UniProtKB:Q9BZI7] synonym: "hUpf3p-X" EXACT [UniProtKB:Q9BZI7] synonym: "Nonsense mRNA reducing factor 3B" EXACT [UniProtKB:Q9BZI7] synonym: "Up-frameshift suppressor 3 homolog B" EXACT [UniProtKB:Q9BZI7] xref: EMBL:AAG48511.1 xref: EMBL:AAG60691.1 xref: EMBL:AAI21018.1 xref: UniProtKB:Q0VAK8 xref: UniProtKB:Q9BZI7 xref: UniProtKB:Q9H1J0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005466 ! UPF3B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001632 ! nucleocytoplasmic transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006231 ! upf1-dcp1a-2 physical interaction relationship: participates_in CCO:I0006239 ! upf1-dcp1a-3 physical interaction relationship: participates_in CCO:I0006240 ! upf1-dcp1a-4 physical interaction relationship: participates_in CCO:I0007249 ! rent1-stau-6 physical interaction relationship: participates_in CCO:I0018484 ! ddx48-eif4gi physical interaction relationship: participates_in CCO:I0018485 ! eif4gi-q9h1j2 physical interaction relationship: participates_in CCO:I0020046 ! itgb3bp-upf3b physical interaction relationship: transforms_into CCO:B0069859 ! REN3B_HUMAN-Phosphothreonine169 [Term] id: CCO:B0005435 name: RENT2_HUMAN def: "Regulator of nonsense transcripts 2" [UniProtKB:Q9HAU5] synonym: "hUpf2" EXACT [UniProtKB:Q9HAU5] synonym: "Nonsense mRNA reducing factor 2" EXACT [UniProtKB:Q9HAU5] synonym: "Up-frameshift suppressor 2 homolog" EXACT [UniProtKB:Q9HAU5] xref: EMBL:AAG33225.1 xref: EMBL:AAG48509.1 xref: EMBL:AAG60689.1 xref: EMBL:AAI14965.1 xref: EMBL:AAI15738.1 xref: EMBL:BAA91369.1 xref: EMBL:BAA92646.1 xref: EMBL:BAC04721.1 xref: EMBL:CAB45771.1 xref: EMBL:CAH73458.1 xref: EMBL:CAH73459.1 xref: EMBL:CAI16755.1 xref: EMBL:CAI16756.1 xref: UniProtKB:A6NLJ5 xref: UniProtKB:Q14BM1 xref: UniProtKB:Q5W0J4 xref: UniProtKB:Q8N8U1 xref: UniProtKB:Q9H1J2 xref: UniProtKB:Q9HAU5 xref: UniProtKB:Q9NWL1 xref: UniProtKB:Q9P2D9 xref: UniProtKB:Q9Y4M9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005468 ! UPF2_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006231 ! upf1-dcp1a-2 physical interaction relationship: participates_in CCO:I0006239 ! upf1-dcp1a-3 physical interaction relationship: participates_in CCO:I0007249 ! rent1-stau-6 physical interaction [Term] id: CCO:B0005436 name: REN3A_HUMAN def: "Regulator of nonsense transcripts 3A" [UniProtKB:Q9H1J1] synonym: "hUpf3" EXACT [UniProtKB:Q9H1J1] synonym: "Nonsense mRNA reducing factor 3A" EXACT [UniProtKB:Q9H1J1] synonym: "Up-frameshift suppressor 3 homolog A" EXACT [UniProtKB:Q9H1J1] xref: EMBL:AAG48510.1 xref: EMBL:AAG60690.1 xref: EMBL:AAH08694.1 xref: EMBL:AAH23569.1 xref: UniProtKB:Q5T8C3 xref: UniProtKB:Q5T8C9 xref: UniProtKB:Q7Z6N3 xref: UniProtKB:Q86YK1 xref: UniProtKB:Q9BZI8 xref: UniProtKB:Q9H1J1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005465 ! UPF3A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001632 ! nucleocytoplasmic transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006231 ! upf1-dcp1a-2 physical interaction relationship: participates_in CCO:I0006239 ! upf1-dcp1a-3 physical interaction relationship: participates_in CCO:I0006240 ! upf1-dcp1a-4 physical interaction relationship: transforms_into CCO:B0036027 ! REN3A_HUMAN-Phosphoserine68 [Term] id: CCO:B0005437 name: BMR1A_HUMAN def: "Bone morphogenetic protein receptor type-1A precursor" [UniProtKB:P36894] synonym: "Activin receptor-like kinase 3" EXACT [UniProtKB:P36894] synonym: "ALK-3" EXACT [UniProtKB:P36894] synonym: "CD292 antigen" EXACT [UniProtKB:P36894] synonym: "EC 2.7.11.30" EXACT [UniProtKB:P36894] synonym: "Serine/threonine-protein kinase receptor R5" EXACT [UniProtKB:P36894] synonym: "SKR5" EXACT [UniProtKB:P36894] xref: EMBL:AAH28383.1 xref: EMBL:CAA80257.1 xref: UniProtKB:P36894 xref: UniProtKB:Q8NEN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004174 ! BMPR1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006232 ! bmp2-bmpr1a-1 direct interaction relationship: participates_in CCO:I0007709 ! bmp2-bmpr1a-2 direct interaction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: transforms_into CCO:B0010811 ! BMR1A_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0010812 ! BMR1A_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0010813 ! BMR1A_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0010814 ! BMR1A_HUMAN-Phosphoserine220 [Term] id: CCO:B0005438 name: MET_HUMAN def: "Hepatocyte growth factor receptor precursor" [UniProtKB:P08581] synonym: "c-Met" EXACT [UniProtKB:P08581] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P08581] synonym: "HGF receptor" EXACT [UniProtKB:P08581] synonym: "HGF/SF receptor" EXACT [UniProtKB:P08581] synonym: "Met proto-oncogene tyrosine kinase" EXACT [UniProtKB:P08581] synonym: "Scatter factor receptor" EXACT [UniProtKB:P08581] synonym: "SF receptor" EXACT [UniProtKB:P08581] xref: EMBL:AAA59590.1 xref: EMBL:AAA59591.1 xref: EMBL:AAB54047.1 xref: EMBL:AAB60323.1 xref: EMBL:AAC60383.1 xref: EMBL:AAF66137.2 xref: EMBL:CAB56793.1 xref: UniProtKB:O60366 xref: UniProtKB:P08581 xref: UniProtKB:Q12875 xref: UniProtKB:Q9UDX7 xref: UniProtKB:Q9UPL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005086 ! MET_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006236 ! hgf-met-1 direct interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002758 ! hepatocyte growth factor receptor signaling pathway relationship: participates_in CCO:P0003091 ! myoblast proliferation relationship: transforms_into CCO:B0012911 ! MET_HUMAN-Phosphothreonine977 relationship: transforms_into CCO:B0012912 ! MET_HUMAN-Phosphoserine988 relationship: transforms_into CCO:B0012913 ! MET_HUMAN-Phosphoserine990 relationship: transforms_into CCO:B0012914 ! MET_HUMAN-Phosphotyrosine1003 relationship: transforms_into CCO:B0012915 ! MET_HUMAN-Phosphotyrosine1235 relationship: transforms_into CCO:B0012916 ! MET_HUMAN-Phosphotyrosine1356 relationship: transforms_into CCO:B0068149 ! MET_HUMAN-Phosphotyrosine1230 relationship: transforms_into CCO:B0068150 ! MET_HUMAN-Phosphotyrosine1234 [Term] id: CCO:B0005440 name: FBX25_HUMAN def: "F-box only protein 25" [UniProtKB:Q8TCJ0] xref: EMBL:AAF04526.1 xref: EMBL:AAH20249.1 xref: EMBL:AAH50393.1 xref: EMBL:AAP97293.1 xref: EMBL:BAB85128.1 xref: UniProtKB:Q6PJ83 xref: UniProtKB:Q7Z4V4 xref: UniProtKB:Q8TCJ0 xref: UniProtKB:Q9UKB8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004623 ! FBXO25_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006242 ! fbxo25-cul1-1 physical interaction [Term] id: CCO:B0005441 name: FBX4_HUMAN def: "F-box only protein 4" [UniProtKB:Q9UKT5] xref: EMBL:AAF03703.1 xref: EMBL:AAF04468.1 xref: EMBL:AAH48098.1 xref: EMBL:CAH18486.1 xref: UniProtKB:Q68CU8 xref: UniProtKB:Q86VT8 xref: UniProtKB:Q9UK98 xref: UniProtKB:Q9UKT5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004625 ! FBXO4_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: participates_in CCO:I0006243 ! fbxo4-cul1-2 physical interaction relationship: transforms_into CCO:B0011870 ! FBX4_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0011871 ! FBX4_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0011872 ! FBX4_HUMAN-Phosphothreonine239 relationship: transforms_into CCO:B0011873 ! FBX4_HUMAN-Phosphothreonine240 [Term] id: CCO:B0005442 name: FBX7_HUMAN def: "F-box only protein 7" [UniProtKB:Q9Y3I1] xref: EMBL:AAF04471.1 xref: EMBL:AAF67155.1 xref: EMBL:AAH08361.1 xref: EMBL:CAB43356.1 xref: EMBL:CAG30377.1 xref: EMBL:CAI18782.1 xref: EMBL:CAI19333.1 xref: EMBL:CAI19587.1 xref: UniProtKB:Q5TGC4 xref: UniProtKB:Q96HM6 xref: UniProtKB:Q9UF21 xref: UniProtKB:Q9UKT2 xref: UniProtKB:Q9Y3I1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004627 ! FBXO7_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0006244 ! fbxo7-cul1-1 physical interaction relationship: participates_in CCO:P0001482 ! regulation of protein stability [Term] id: CCO:B0005443 name: PARK7_HUMAN def: "Protein DJ-1" [UniProtKB:Q99497] synonym: "Oncogene DJ1" EXACT [UniProtKB:Q99497] synonym: "Parkinson disease protein 7" EXACT [UniProtKB:Q99497] xref: EMBL:AAC12806.1 xref: EMBL:AAH08188.1 xref: EMBL:AAT68961.1 xref: EMBL:BAA09603.2 xref: EMBL:BAB71782.1 xref: EMBL:CAB52550.1 xref: UniProtKB:O14805 xref: UniProtKB:Q6DR95 xref: UniProtKB:Q7LFU2 xref: UniProtKB:Q99497 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005267 ! PARK7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006245 ! dj_1-daxx-2 physical interaction relationship: participates_in CCO:I0006929 ! dj_1-daxx-3 colocalization relationship: participates_in CCO:I0007173 ! dj_1-ubc9 physical interaction relationship: participates_in CCO:I0007174 ! dj_1-daxx-1 physical interaction relationship: participates_in CCO:I0018262 ! dj_1-dj_1 physical interaction relationship: participates_in CCO:I0018263 ! dj_1-uba2 physical interaction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0013396 ! PARK7_HUMAN-Phosphotyrosine67 relationship: transforms_into CCO:B0013397 ! PARK7_HUMAN-Cysteine sulfinic acid (-SO2H)106 [Term] id: CCO:B0005444 name: CHD8_HUMAN def: "Chromodomain-helicase-DNA-binding protein 8" [UniProtKB:Q9HCK8] synonym: "ATP-dependent helicase CHD8" EXACT [UniProtKB:Q9HCK8] synonym: "CHD-8" EXACT [UniProtKB:Q9HCK8] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9HCK8] synonym: "Helicase with SNF2 domain 1" EXACT [UniProtKB:Q9HCK8] xref: EMBL:AAH11695.2 xref: EMBL:AAH25964.1 xref: EMBL:AAH36920.1 xref: EMBL:BAB13390.3 xref: EMBL:CAD39180.1 xref: EMBL:CAH18170.1 xref: UniProtKB:Q68DQ0 xref: UniProtKB:Q8N3Z9 xref: UniProtKB:Q8NCY4 xref: UniProtKB:Q8TBR9 xref: UniProtKB:Q96F26 xref: UniProtKB:Q9HCK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004345 ! CHD8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006247 ! ctcf-chd8-5 colocalization relationship: participates_in CCO:I0006781 ! ctcf-chd8-3 physical interaction relationship: participates_in CCO:I0006782 ! ctcf-chd8-4 colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011204 ! CHD8_HUMAN-Phosphothreonine258 relationship: transforms_into CCO:B0011205 ! CHD8_HUMAN-Phosphothreonine1119 relationship: transforms_into CCO:B0011206 ! CHD8_HUMAN-Phosphoserine1141 relationship: transforms_into CCO:B0011207 ! CHD8_HUMAN-Phosphoserine1145 relationship: transforms_into CCO:B0011208 ! CHD8_HUMAN-Phosphoserine1790 relationship: transforms_into CCO:B0011209 ! CHD8_HUMAN-Phosphoserine1792 relationship: transforms_into CCO:B0048195 ! CHD8_HUMAN-Phosphoserine1903 relationship: transforms_into CCO:B0048196 ! CHD8_HUMAN-Phosphoserine1921 relationship: transforms_into CCO:B0048197 ! CHD8_HUMAN-Phosphoserine1923 relationship: transforms_into CCO:B0048198 ! CHD8_HUMAN-Phosphoserine1932 relationship: transforms_into CCO:B0048199 ! CHD8_HUMAN-Phosphoserine2239 relationship: transforms_into CCO:B0048200 ! CHD8_HUMAN-Phosphoserine2240 relationship: transforms_into CCO:B0064334 ! CHD8_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0064335 ! CHD8_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0064336 ! CHD8_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0064337 ! CHD8_HUMAN-Phosphoserine1697 relationship: transforms_into CCO:B0064338 ! CHD8_HUMAN-Phosphoserine1716 relationship: transforms_into CCO:B0064339 ! CHD8_HUMAN-Phosphoserine1729 relationship: transforms_into CCO:B0064340 ! CHD8_HUMAN-Phosphoserine1767 [Term] id: CCO:B0005445 name: SDC2_HUMAN def: "Syndecan-2 precursor" [UniProtKB:P34741] synonym: "Fibroglycan" EXACT [UniProtKB:P34741] synonym: "Heparan sulfate proteoglycan core protein" EXACT [UniProtKB:P34741] synonym: "HSPG" EXACT [UniProtKB:P34741] synonym: "SYND2" EXACT [UniProtKB:P34741] xref: EMBL:AAA52701.1 xref: EMBL:AAH49836.1 xref: EMBL:BAB15150.1 xref: UniProtKB:P34741 xref: UniProtKB:Q9H6V1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005576 ! SDC2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006248 ! nf1-sdc2 physical interaction relationship: participates_in CCO:I0006249 ! nf1-sdc2-1 physical interaction relationship: participates_in CCO:I0006250 ! nf1-sdc2-3 physical interaction relationship: participates_in CCO:I0006251 ! nf1-sdc2-4 physical interaction [Term] id: CCO:B0005446 name: AATF_HUMAN def: "Protein AATF" [UniProtKB:Q9NY61] synonym: "Apoptosis-antagonizing transcription factor" EXACT [UniProtKB:Q9NY61] synonym: "Rb-binding protein Che-1" EXACT [UniProtKB:Q9NY61] xref: EMBL:AAD52016.1 xref: EMBL:AAF28955.1 xref: EMBL:AAH00591.1 xref: EMBL:CAB57451.2 xref: EMBL:EAW57575.1 xref: UniProtKB:A6NCJ6 xref: UniProtKB:Q9NY61 xref: UniProtKB:Q9P0A4 xref: UniProtKB:Q9UNX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004009 ! AATF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006252 ! atm-aatf-1 phosphorylation relationship: participates_in CCO:I0006253 ! atr-aatf-2 phosphorylation relationship: participates_in CCO:I0006254 ! chek2-aatf-2 phosphorylation relationship: participates_in CCO:I0006255 ! chek1-aatf phosphorylation relationship: participates_in CCO:I0006256 ! atm-aatf-2 phosphorylation relationship: participates_in CCO:I0006257 ! chek2-aatf-3 phosphorylation relationship: participates_in CCO:I0006492 ! mphosph6-ded physical interaction relationship: participates_in CCO:I0007041 ! chek2-aatf physical interaction relationship: participates_in CCO:I0007178 ! chek2-aatf-1 physical interaction relationship: participates_in CCO:I0007945 ! atm-aatf physical interaction relationship: participates_in CCO:I0015261 ! aatf-dazap2 physical interaction relationship: participates_in CCO:I0015346 ! aatf-ldoc1 physical interaction relationship: participates_in CCO:I0017972 ! rela-aatf-2 physical interaction relationship: participates_in CCO:I0018126 ! rela-aatf physical interaction relationship: participates_in CCO:I0018127 ! rela-aatf-1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0010391 ! AATF_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0010392 ! AATF_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0010393 ! AATF_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0010394 ! AATF_HUMAN-Phosphoserine321 [Term] id: CCO:B0005447 name: NRP1_HUMAN def: "Neuropilin-1 precursor" [UniProtKB:O14786] synonym: "CD304 antigen" EXACT [UniProtKB:O14786] synonym: "Vascular endothelial cell growth factor 165 receptor" EXACT [UniProtKB:O14786] xref: EMBL:AAC12921.1 xref: EMBL:AAC51759.1 xref: EMBL:AAF44344.1 xref: EMBL:AAH07533.1 xref: EMBL:AAP35641.1 xref: EMBL:CAI16997.1 xref: EMBL:CAI40248.1 xref: UniProtKB:O14786 xref: UniProtKB:O60461 xref: UniProtKB:Q5T7F3 xref: UniProtKB:Q96IH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005214 ! NRP1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006259 ! nrp1-vegf physical interaction relationship: participates_in CCO:I0017809 ! kdr-nrp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0068856 ! NRP1_HUMAN-Phosphotyrosine920 [Term] id: CCO:B0005448 name: CLCA_HUMAN def: "Clathrin light chain A" [UniProtKB:P09496] synonym: "Lca" EXACT [UniProtKB:P09496] xref: EMBL:AAA51817.1 xref: EMBL:AAA59505.1 xref: EMBL:AAH09201.1 xref: EMBL:AAH19287.1 xref: EMBL:AAP35834.1 xref: EMBL:ABB76683.1 xref: EMBL:CAD13387.1 xref: EMBL:CAD13388.1 xref: UniProtKB:P09496 xref: UniProtKB:Q2XPN5 xref: UniProtKB:Q53XZ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004368 ! CLTA_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000963 ! clathrin coat relationship: located_in CCO:C0000975 ! clathrin coat of trans-Golgi network vesicle relationship: located_in CCO:C0000977 ! clathrin coat of coated pit relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction [Term] id: CCO:B0005449 name: TBA4A_HUMAN def: "Tubulin alpha-4A chain" [UniProtKB:P68366] synonym: "Alpha-tubulin 1" EXACT [UniProtKB:P68366] synonym: "Testis-specific alpha-tubulin" EXACT [UniProtKB:P68366] synonym: "Tubulin alpha-1 chain" EXACT [UniProtKB:P68366] synonym: "Tubulin H2-alpha" EXACT [UniProtKB:P68366] xref: EMBL:AAH09238.1 xref: EMBL:AAP35377.1 xref: EMBL:AAW65371.1 xref: EMBL:CAA30026.1 xref: UniProtKB:P05215 xref: UniProtKB:P68366 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005732 ! TUBA4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0019644 ! actn2-tuba1 physical interaction relationship: participates_in CCO:I0019924 ! bcar1-tuba1 physical interaction relationship: participates_in CCO:I0020010 ! gnai2-tuba1 physical interaction relationship: participates_in CCO:I0020064 ! maged1-tuba1 physical interaction relationship: transforms_into CCO:B0014312 ! TBA4A_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0014313 ! TBA4A_HUMAN-Phosphotyrosine161 relationship: transforms_into CCO:B0014314 ! TBA4A_HUMAN-Phosphotyrosine272 relationship: transforms_into CCO:B0031377 ! TBA4A_HUMAN-Phosphotyrosine319 relationship: transforms_into CCO:B0041205 ! TBA4A_HUMAN-Phosphoserine439 relationship: transforms_into CCO:B0041206 ! TBA4A_HUMAN-Phosphotyrosine440 relationship: transforms_into CCO:B0071206 ! TBA4A_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0071207 ! TBA4A_HUMAN-Phosphoserine340 [Term] id: CCO:B0005450 name: ICAM1_HUMAN def: "Intercellular adhesion molecule 1 precursor" [UniProtKB:P05362] synonym: "CD54 antigen" EXACT [UniProtKB:P05362] synonym: "ICAM-1" EXACT [UniProtKB:P05362] synonym: "Major group rhinovirus receptor" EXACT [UniProtKB:P05362] xref: EMBL:AAA52708.1 xref: EMBL:AAA52709.1 xref: EMBL:AAH15969.1 xref: EMBL:AAO30128.1 xref: EMBL:AAP35500.1 xref: EMBL:AAQ14902.1 xref: EMBL:CAA30051.1 xref: EMBL:CAA40441.1 xref: EMBL:CAA41977.1 xref: UniProtKB:P05362 xref: UniProtKB:Q5NKV7 xref: UniProtKB:Q96B50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004847 ! ICAM1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0017954 ! icam1-itgal-1 direct interaction relationship: participates_in CCO:P0001245 ! regulation of cell adhesion [Term] id: CCO:B0005451 name: HXC10_HUMAN def: "Homeobox protein Hox-C10" [UniProtKB:Q9NYD6] xref: EMBL:AAF67759.1 xref: EMBL:AAH01293.1 xref: EMBL:CAA67999.1 xref: EMBL:CAA68000.1 xref: UniProtKB:O15219 xref: UniProtKB:O15220 xref: UniProtKB:Q9BVD5 xref: UniProtKB:Q9NYD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004845 ! HOXC10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000901 ! cyclin-dependent protein kinase activating kinase holoenzyme complex relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066964 ! HXC10_HUMAN-Phosphoserine189 [Term] id: CCO:B0005452 name: SEC13_HUMAN def: "Protein SEC13 homolog" [UniProtKB:P55735] synonym: "SEC13-like protein 1" EXACT [UniProtKB:P55735] synonym: "SEC13-related protein" EXACT [UniProtKB:P55735] xref: EMBL:AAH02634.2 xref: EMBL:AAH06167.1 xref: EMBL:AAH91506.1 xref: UniProtKB:P55735 xref: UniProtKB:Q5BJF0 xref: UniProtKB:Q9BRM6 xref: UniProtKB:Q9BUG7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005578 ! SEC13_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0016951 ! q9nyj8-sec13l1 physical interaction [Term] id: CCO:B0005453 name: AT1B1_HUMAN def: "Sodium/potassium-transporting ATPase subunit beta-1" [UniProtKB:P05026] synonym: "Sodium/potassium-dependent ATPase subunit beta-1" EXACT [UniProtKB:P05026] xref: EMBL:AAA36352.1 xref: EMBL:AAC50132.1 xref: EMBL:AAH00006.1 xref: EMBL:AAP88789.1 xref: EMBL:CAA27385.1 xref: EMBL:CAA35040.1 xref: EMBL:CAI18888.1 xref: UniProtKB:P05026 xref: UniProtKB:Q5TGZ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004112 ! ATP1B1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0008193 ! atp1b1-rif1 physical interaction relationship: transforms_into CCO:B0031296 ! AT1B1_HUMAN-Phosphotyrosine101 [Term] id: CCO:B0005454 name: GRB2_HUMAN def: "Growth factor receptor-bound protein 2" [UniProtKB:P62993] synonym: "Adapter protein GRB2" EXACT [UniProtKB:P62993] synonym: "Protein Ash" EXACT [UniProtKB:P62993] synonym: "SH2/SH3 adapter GRB2" EXACT [UniProtKB:P62993] xref: EMBL:AAA58448.1 xref: EMBL:AAC37549.1 xref: EMBL:AAC72075.1 xref: EMBL:AAH00631.1 xref: EMBL:AAM21073.1 xref: EMBL:CAA44664.1 xref: EMBL:CAG46740.1 xref: UniProtKB:P29354 xref: UniProtKB:P62993 xref: UniProtKB:Q14450 xref: UniProtKB:Q63057 xref: UniProtKB:Q63059 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004725 ! GRB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0006278 ! egfr-grb2 physical interaction relationship: participates_in CCO:I0006618 ! khdrbs1-grb2-1 physical interaction relationship: participates_in CCO:I0006621 ! khdrbs1-grb2-2 physical interaction relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0006842 ! egfr-grb2-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007453 ! gab2-grb2-1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0007966 ! grb2-sam68-1 physical interaction relationship: participates_in CCO:I0007967 ! grb2-sam68-2 physical interaction relationship: participates_in CCO:I0015980 ! ptpn6-grb2-1 physical interaction relationship: participates_in CCO:I0016108 ! map4k5-grb2-1 physical interaction relationship: participates_in CCO:I0017397 ! grb2-dnm1-4 physical interaction relationship: participates_in CCO:I0017633 ! grb2-npm_alk physical interaction relationship: participates_in CCO:I0017810 ! med28-grb2-4 direct interaction relationship: participates_in CCO:I0017833 ! sos1-grb2-1 physical interaction relationship: participates_in CCO:I0017837 ! sos2-grb2-1 physical interaction relationship: participates_in CCO:I0017907 ! ephb1-grb10-3 physical interaction relationship: participates_in CCO:I0018210 ! ephb1-grb2-2 physical interaction relationship: participates_in CCO:I0018468 ! bat2-grb2 physical interaction relationship: participates_in CCO:I0018645 ! grb2-vav1-1 physical interaction relationship: participates_in CCO:I0019216 ! sos2-grb2-2 physical interaction relationship: participates_in CCO:I0019219 ! sos1-grb2-2 physical interaction relationship: participates_in CCO:I0019298 ! st5-grb2-1 physical interaction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0011973 ! GRB2_HUMAN-Phosphotyrosine160 relationship: transforms_into CCO:B0011974 ! GRB2_HUMAN-Phosphotyrosine209 relationship: transforms_into CCO:B0066585 ! GRB2_HUMAN-Phosphothreonine211 [Term] id: CCO:B0005455 name: CD166_HUMAN def: "CD166 antigen precursor" [UniProtKB:Q13740] synonym: "Activated leukocyte cell adhesion molecule" EXACT [UniProtKB:Q13740] synonym: "CD166 antigen" EXACT [UniProtKB:Q13740] xref: EMBL:AAB59499.1 xref: EMBL:ABF48405.1 xref: EMBL:ABF48406.1 xref: EMBL:CAA71256.1 xref: UniProtKB:O60892 xref: UniProtKB:Q13740 xref: UniProtKB:Q1HGM8 xref: UniProtKB:Q1HGM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004269 ! ALCAM_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005456 name: CAV1_HUMAN def: "Caveolin-1" [UniProtKB:Q03135] xref: EMBL:AAD23745.1 xref: EMBL:AAD34722.1 xref: EMBL:AAH09685.1 xref: EMBL:AAH82246.1 xref: EMBL:AAP35807.1 xref: EMBL:CAA79476.1 xref: EMBL:CAB63654.1 xref: UniProtKB:Q03135 xref: UniProtKB:Q9UGP1 xref: UniProtKB:Q9UNG1 xref: UniProtKB:Q9UQH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004224 ! CAV1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0015863 ! scp2-cav1-3 physical interaction relationship: participates_in CCO:I0015864 ! cav1-scp2-3 physical interaction relationship: participates_in CCO:I0015939 ! cav2-cav1-1 physical interaction relationship: participates_in CCO:I0015940 ! flot1-cav1-1 physical interaction relationship: participates_in CCO:I0015941 ! flot2-cav1-1 physical interaction relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0001140 ! regulation of fatty acid metabolic process relationship: participates_in CCO:P0001343 ! negative regulation of epithelial cell differentiation relationship: participates_in CCO:P0002210 ! negative regulation of MAPKKK cascade relationship: participates_in CCO:P0002262 ! negative regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0002693 ! negative regulation of JAK-STAT cascade relationship: transforms_into CCO:B0010929 ! CAV1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: transforms_into CCO:B0010931 ! CAV1_HUMAN-Phosphotyrosine14 relationship: transforms_into CCO:B0010932 ! CAV1_HUMAN-Phosphotyrosine25 relationship: transforms_into CCO:B0010933 ! CAV1_HUMAN-Phosphoserine37 [Term] id: CCO:B0005457 name: LYN_HUMAN def: "Tyrosine-protein kinase Lyn" [UniProtKB:P07948] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P07948] xref: EMBL:AAA59540.1 xref: EMBL:AAB50019.1 xref: EMBL:AAH75001.1 xref: EMBL:AAH75002.1 xref: EMBL:AAI26457.1 xref: EMBL:AAI26459.1 xref: UniProtKB:A0AVQ5 xref: UniProtKB:P07948 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004998 ! LYN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0006712 ! khdrbs1-lyn-1 physical interaction relationship: participates_in CCO:I0006944 ! cdkn1b-lyn-2 phosphorylation relationship: participates_in CCO:I0007486 ! cdkn1b-lyn-1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:I0016743 ! map3k3-lyn physical interaction relationship: participates_in CCO:I0017641 ! cd22-lyn-1 physical interaction relationship: participates_in CCO:I0017642 ! lyn-cd22-1 physical interaction relationship: participates_in CCO:I0018455 ! csnk2b-lyn physical interaction relationship: participates_in CCO:I0018696 ! sphk2-lyn-1 direct interaction relationship: participates_in CCO:I0019281 ! lyn-lyn-2 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: transforms_into CCO:B0012709 ! LYN_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0012710 ! LYN_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0012711 ! LYN_HUMAN-Phosphotyrosine397 relationship: transforms_into CCO:B0012712 ! LYN_HUMAN-Phosphotyrosine508 relationship: transforms_into CCO:B0031336 ! LYN_HUMAN-Phosphotyrosine193 relationship: transforms_into CCO:B0031337 ! LYN_HUMAN-Phosphotyrosine194 relationship: transforms_into CCO:B0067800 ! LYN_HUMAN-Phosphotyrosine306 relationship: transforms_into CCO:B0067801 ! LYN_HUMAN-Phosphotyrosine473 [Term] id: CCO:B0005458 name: G3P_HUMAN def: "Glyceraldehyde-3-phosphate dehydrogenase" [UniProtKB:P04406] synonym: "EC 1.2.1.12" EXACT [UniProtKB:P04406] synonym: "GAPDH" EXACT [UniProtKB:P04406] xref: EMBL:AAA52496.1 xref: EMBL:AAA52518.1 xref: EMBL:AAA53191.1 xref: EMBL:AAA86283.1 xref: EMBL:AAF99678.1 xref: EMBL:AAG01996.1 xref: EMBL:AAH01601.1 xref: EMBL:AAH04109.1 xref: EMBL:AAH09081.1 xref: EMBL:AAH13310.1 xref: EMBL:AAH23632.1 xref: EMBL:AAH25925.1 xref: EMBL:AAH26907.1 xref: EMBL:AAH29618.1 xref: EMBL:AAH83511.1 xref: EMBL:AAP35539.1 xref: EMBL:AAP88932.1 xref: EMBL:BAB93466.1 xref: EMBL:CAA25833.1 xref: EMBL:CAA37794.1 xref: UniProtKB:P00354 xref: UniProtKB:P04406 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004669 ! GAPDH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: participates_in CCO:I0016047 ! gapd-htatip physical interaction relationship: participates_in CCO:I0016367 ! rel-gapd physical interaction relationship: participates_in CCO:I0016757 ! map3k3-gapd physical interaction relationship: participates_in CCO:I0016918 ! ripk2-gapd physical interaction relationship: participates_in CCO:I0016978 ! tbk1-gapd physical interaction relationship: participates_in CCO:I0017109 ! traf1-gapd physical interaction relationship: transforms_into CCO:B0011913 ! G3P_HUMAN-Phosphotyrosine42 relationship: transforms_into CCO:B0011914 ! G3P_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0011915 ! G3P_HUMAN-Phosphothreonine211 relationship: transforms_into CCO:B0031322 ! G3P_HUMAN-Phosphotyrosine314 relationship: transforms_into CCO:B0031323 ! G3P_HUMAN-Phosphotyrosine320 relationship: transforms_into CCO:B0048269 ! G3P_HUMAN-ADP-ribosylcysteine152 relationship: transforms_into CCO:B0048270 ! G3P_HUMAN-S-nitrosocysteine152 [Term] id: CCO:B0005459 name: AT1A1_HUMAN def: "Sodium/potassium-transporting ATPase subunit alpha-1 precursor" [UniProtKB:P05023] synonym: "EC 3.6.3.9" EXACT [UniProtKB:P05023] synonym: "Na(+)/K(+) ATPase alpha-1 subunit" EXACT [UniProtKB:P05023] synonym: "Sodium pump subunit alpha-1" EXACT [UniProtKB:P05023] xref: EMBL:AAA35573.1 xref: EMBL:AAA35574.2 xref: EMBL:AAA51801.1 xref: EMBL:AAA51803.1 xref: EMBL:AAA92713.1 xref: EMBL:AAC50131.1 xref: EMBL:AAD56251.1 xref: EMBL:AAD56252.1 xref: EMBL:AAH01330.1 xref: EMBL:AAH03077.1 xref: EMBL:AAH50359.1 xref: EMBL:BAA00061.1 xref: EMBL:CAA27390.1 xref: EMBL:CAA27840.1 xref: EMBL:CAI22199.1 xref: UniProtKB:P05023 xref: UniProtKB:Q16689 xref: UniProtKB:Q6LDM4 xref: UniProtKB:Q9UJ20 xref: UniProtKB:Q9UJ21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004111 ! ATP1A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0016989 ! tnfrsf1a-atp1a1 physical interaction relationship: participates_in CCO:I0017061 ! tradd-atp1a1 physical interaction relationship: transforms_into CCO:B0010633 ! AT1A1_HUMAN-Phosphotyrosine10 relationship: transforms_into CCO:B0010634 ! AT1A1_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0010635 ! AT1A1_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0010636 ! AT1A1_HUMAN-Phosphoserine217 relationship: transforms_into CCO:B0010637 ! AT1A1_HUMAN-Phosphothreonine219 relationship: transforms_into CCO:B0010638 ! AT1A1_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0010639 ! AT1A1_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0010640 ! AT1A1_HUMAN-Phosphoserine943 relationship: transforms_into CCO:B0031295 ! AT1A1_HUMAN-Phosphotyrosine260 [Term] id: CCO:B0005460 name: CLH2_HUMAN def: "Clathrin heavy chain 2" [UniProtKB:P53675] synonym: "CLH-22" EXACT [UniProtKB:P53675] xref: EMBL:AAB40908.1 xref: EMBL:AAB40909.1 xref: EMBL:AAC50494.1 xref: EMBL:CAA64752.1 xref: EMBL:CAA64753.1 xref: UniProtKB:P53675 xref: UniProtKB:Q14017 xref: UniProtKB:Q15808 xref: UniProtKB:Q15809 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004369 ! CLTCL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0017009 ! tnfrsf1a-cltcl1 physical interaction relationship: transforms_into CCO:B0011260 ! CLH2_HUMAN-Phosphothreonine103 [Term] id: CCO:B0005461 name: S10A9_HUMAN def: "Protein S100-A9" [UniProtKB:P06702] synonym: "Calgranulin-B" EXACT [UniProtKB:P06702] synonym: "Calprotectin L1H subunit" EXACT [UniProtKB:P06702] synonym: "Leukocyte L1 complex heavy chain" EXACT [UniProtKB:P06702] synonym: "Migration inhibitory factor-related protein 14" EXACT [UniProtKB:P06702] synonym: "MRP-14" EXACT [UniProtKB:P06702] synonym: "P14" EXACT [UniProtKB:P06702] synonym: "S100 calcium-binding protein A9" EXACT [UniProtKB:P06702] xref: EMBL:AAA36326.1 xref: EMBL:AAA68480.1 xref: EMBL:AAF62536.1 xref: EMBL:AAF62537.1 xref: EMBL:AAH47681.1 xref: EMBL:CAA29579.1 xref: EMBL:CAG47003.1 xref: EMBL:CAG47020.1 xref: EMBL:CAI19494.1 xref: UniProtKB:P06702 xref: UniProtKB:Q6FGA1 xref: UniProtKB:Q9NYM0 xref: UniProtKB:Q9UCJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005554 ! S100A9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: participates_in CCO:P0002280 ! regulation of integrin biosynthetic process relationship: transforms_into CCO:B0013949 ! S10A9_HUMAN-Phosphothreonine113 relationship: transforms_into CCO:B0041180 ! S10A9_HUMAN-Blocked amino end (Thr)2 [Term] id: CCO:B0005462 name: CAV2_HUMAN def: "Caveolin-2" [UniProtKB:P51636] xref: EMBL:AAB88492.1 xref: EMBL:AAH05256.1 xref: EMBL:AAP35700.1 xref: EMBL:CAB63653.1 xref: EMBL:CAB65090.1 xref: UniProtKB:P51636 xref: UniProtKB:Q9UGM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004225 ! CAV2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0015939 ! cav2-cav1-1 physical interaction relationship: participates_in CCO:I0020567 ! golgb1-cav2 physical interaction relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization relationship: transforms_into CCO:B0010934 ! CAV2_HUMAN-Phosphotyrosine19 relationship: transforms_into CCO:B0010935 ! CAV2_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0010936 ! CAV2_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: transforms_into CCO:B0010938 ! CAV2_HUMAN-Phosphoserine36 [Term] id: CCO:B0005463 name: 4F2_HUMAN def: "4F2 cell-surface antigen heavy chain" [UniProtKB:P08195] synonym: "4F2 heavy chain antigen" EXACT [UniProtKB:P08195] synonym: "4F2hc" EXACT [UniProtKB:P08195] synonym: "CD98 antigen" EXACT [UniProtKB:P08195] synonym: "Lymphocyte activation antigen 4F2 large subunit" EXACT [UniProtKB:P08195] xref: EMBL:AAA35489.1 xref: EMBL:AAA35536.1 xref: EMBL:AAA51540.1 xref: EMBL:AAA52497.1 xref: EMBL:AAH01061.2 xref: EMBL:AAH03000.2 xref: EMBL:BAA84649.1 xref: UniProtKB:P08195 xref: UniProtKB:Q13543 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004005 ! SLC3A2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006261 ! egfr-calm-cav1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007516 ! egfr-cav1-clca physical interaction relationship: transforms_into CCO:B0010380 ! 4F2_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0010381 ! 4F2_HUMAN-Phosphothreonine5 [Term] id: CCO:B0005464 name: SRC_HUMAN def: "Proto-oncogene tyrosine-protein kinase Src" [UniProtKB:P12931] synonym: "c-Src" EXACT [UniProtKB:P12931] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P12931] synonym: "p60-Src" EXACT [UniProtKB:P12931] synonym: "pp60c-src" EXACT [UniProtKB:P12931] xref: EMBL:AAA60584.1 xref: EMBL:AAH11566.1 xref: EMBL:AAH51270.2 xref: EMBL:CAA26485.1 xref: EMBL:CAC34523.1 xref: UniProtKB:P12931 xref: UniProtKB:Q86VB9 xref: UniProtKB:Q9H5A8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005670 ! SRC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006262 ! src-cdn1b-1 phosphorylation relationship: participates_in CCO:I0008166 ! src-khdrbs1 physical interaction relationship: participates_in CCO:I0015982 ! src-actn1-1 physical interaction relationship: participates_in CCO:I0017832 ! src-med28-1 physical interaction relationship: participates_in CCO:I0018671 ! ikka-src-2 physical interaction relationship: participates_in CCO:I0018672 ! ikka-src-1 physical interaction relationship: participates_in CCO:I0018876 ! src-actn1-2 physical interaction relationship: participates_in CCO:I0018877 ! src-fak1-1 physical interaction relationship: participates_in CCO:I0019263 ! ikka-src-3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0014208 ! SRC_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0014209 ! SRC_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0014210 ! SRC_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0014211 ! SRC_HUMAN-Phosphotyrosine419 relationship: transforms_into CCO:B0014212 ! SRC_HUMAN-Phosphotyrosine530 relationship: transforms_into CCO:B0031376 ! SRC_HUMAN-Phosphotyrosine187 relationship: transforms_into CCO:B0041198 ! SRC_HUMAN-Phosphothreonine74 relationship: transforms_into CCO:B0070904 ! SRC_HUMAN-Phosphotyrosine439 [Term] id: CCO:B0005465 name: YES_HUMAN def: "Proto-oncogene tyrosine-protein kinase Yes" [UniProtKB:P07947] synonym: "c-Yes" EXACT [UniProtKB:P07947] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P07947] synonym: "p61-Yes" EXACT [UniProtKB:P07947] xref: EMBL:AAA35735.1 xref: EMBL:AAH48960.1 xref: EMBL:EAX01709.1 xref: UniProtKB:A6NLB3 xref: UniProtKB:P07947 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005949 ! YES1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006263 ! yes-cdn1b-1 phosphorylation relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: transforms_into CCO:B0014729 ! YES_HUMAN-Phosphotyrosine426 relationship: transforms_into CCO:B0014730 ! YES_HUMAN-Phosphotyrosine537 relationship: transforms_into CCO:B0031386 ! YES_HUMAN-Phosphotyrosine194 relationship: transforms_into CCO:B0031387 ! YES_HUMAN-Phosphotyrosine222 relationship: transforms_into CCO:B0071919 ! YES_HUMAN-Phosphotyrosine32 relationship: transforms_into CCO:B0071920 ! YES_HUMAN-Phosphotyrosine223 relationship: transforms_into CCO:B0071921 ! YES_HUMAN-Phosphotyrosine446 [Term] id: CCO:B0005466 name: KU86_HUMAN def: "ATP-dependent DNA helicase 2 subunit 2" [UniProtKB:P13010] synonym: "86 kDa subunit of Ku antigen" EXACT [UniProtKB:P13010] synonym: "ATP-dependent DNA helicase II 80 kDa subunit" EXACT [UniProtKB:P13010] synonym: "CTC box-binding factor 85 kDa subunit" EXACT [UniProtKB:P13010] synonym: "CTC85" EXACT [UniProtKB:P13010] synonym: "CTCBF" EXACT [UniProtKB:P13010] synonym: "DNA repair protein XRCC5" EXACT [UniProtKB:P13010] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P13010] synonym: "Ku80" EXACT [UniProtKB:P13010] synonym: "Ku86" EXACT [UniProtKB:P13010] synonym: "Lupus Ku autoantigen protein p86" EXACT [UniProtKB:P13010] synonym: "Nuclear factor IV" EXACT [UniProtKB:P13010] synonym: "Thyroid-lupus autoantigen" EXACT [UniProtKB:P13010] synonym: "TLAA" EXACT [UniProtKB:P13010] xref: EMBL:AAA36154.1 xref: EMBL:AAA59475.1 xref: EMBL:AAH19027.1 xref: EMBL:AAH95442.1 xref: EMBL:ABG46942.1 xref: EMBL:BAD96323.1 xref: EMBL:BAF83429.1 xref: EMBL:CAA40736.1 xref: EMBL:EAW70562.1 xref: UniProtKB:A8K3X5 xref: UniProtKB:P13010 xref: UniProtKB:Q0Z7V0 xref: UniProtKB:Q4VBQ5 xref: UniProtKB:Q53HH7 xref: UniProtKB:Q7M4N0 xref: UniProtKB:Q9UCQ0 xref: UniProtKB:Q9UCQ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004966 ! XRCC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006264 ! tcf7l2-parp1-5 physical interaction relationship: participates_in CCO:I0006464 ! tcf7l2-parp1 physical interaction relationship: participates_in CCO:I0007054 ! tcf7l2-parp1-1 physical interaction relationship: participates_in CCO:I0007131 ! terf2ip-rad50 physical interaction relationship: participates_in CCO:I0007321 ! g22p1-parp1 physical interaction relationship: participates_in CCO:I0007482 ! tcf7l2-ctnnb1-8 physical interaction relationship: participates_in CCO:I0015955 ! wrn-g22p1-2 physical interaction relationship: participates_in CCO:I0016110 ! g22p1-xrcc5-1 direct interaction relationship: participates_in CCO:I0016111 ! g22p1-xrcc5-2 direct interaction relationship: participates_in CCO:I0016834 ! nfkb2-xrcc5 physical interaction relationship: participates_in CCO:I0017981 ! parp1-wrn-2 adp ribosylation relationship: participates_in CCO:I0018203 ! wrn-g22p1-1 physical interaction relationship: participates_in CCO:I0018335 ! xrcc5-g22p1-1 phosphorylation relationship: participates_in CCO:I0018336 ! wrn-g22p1-3 phosphorylation relationship: participates_in CCO:I0019222 ! wrn-xrcc5-1 physical interaction relationship: participates_in CCO:I0019397 ! wrn-g22p1-4 physical interaction relationship: participates_in CCO:I0019434 ! ku70_80_human direct interaction relationship: participates_in CCO:I0019484 ! wrn-xrcc5-2 physical interaction relationship: transforms_into CCO:B0012653 ! KU86_HUMAN-Phosphoserine577 relationship: transforms_into CCO:B0012654 ! KU86_HUMAN-Phosphoserine579 relationship: transforms_into CCO:B0012655 ! KU86_HUMAN-Phosphoserine580 relationship: transforms_into CCO:B0012656 ! KU86_HUMAN-Phosphothreonine715 [Term] id: CCO:B0005467 name: PARP1_HUMAN def: "Poly [ADP-ribose] polymerase 1" [UniProtKB:P09874] synonym: "ADPRT" EXACT [UniProtKB:P09874] synonym: "EC 2.4.2.30" EXACT [UniProtKB:P09874] synonym: "NAD(+) ADP-ribosyltransferase 1" EXACT [UniProtKB:P09874] synonym: "PARP-1" EXACT [UniProtKB:P09874] synonym: "Poly[ADP-ribose] synthetase 1" EXACT [UniProtKB:P09874] xref: EMBL:AAA51599.1 xref: EMBL:AAA51663.1 xref: EMBL:AAA60000.1 xref: EMBL:AAA60137.1 xref: EMBL:AAA60155.1 xref: EMBL:AAB59447.1 xref: EMBL:AAH37545.1 xref: EMBL:AAM75364.1 xref: EMBL:CAA34663.1 xref: EMBL:CAA39606.1 xref: UniProtKB:P09874 xref: UniProtKB:Q8IUZ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005269 ! PARP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0006264 ! tcf7l2-parp1-5 physical interaction relationship: participates_in CCO:I0006464 ! tcf7l2-parp1 physical interaction relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007054 ! tcf7l2-parp1-1 physical interaction relationship: participates_in CCO:I0007320 ! parp1-tcf7l2-1 physical interaction relationship: participates_in CCO:I0007321 ! g22p1-parp1 physical interaction relationship: participates_in CCO:I0007482 ! tcf7l2-ctnnb1-8 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0016464 ! ikbkb-adprt physical interaction relationship: participates_in CCO:I0016553 ! ikbkg-adprt physical interaction relationship: participates_in CCO:I0016824 ! nfkb2-adprt physical interaction relationship: participates_in CCO:I0017129 ! traf2-adprt physical interaction relationship: participates_in CCO:I0017151 ! traf6-adprt physical interaction relationship: participates_in CCO:I0017311 ! parp1-wrn-1 direct interaction relationship: participates_in CCO:I0017312 ! parp1-xrcc5-1 physical interaction relationship: participates_in CCO:I0017847 ! wrn-parp1-1 physical interaction relationship: participates_in CCO:I0017981 ! parp1-wrn-2 adp ribosylation relationship: participates_in CCO:I0018730 ! parp1-g22p1 physical interaction relationship: participates_in CCO:I0019222 ! wrn-xrcc5-1 physical interaction relationship: participates_in CCO:I0019484 ! wrn-xrcc5-2 physical interaction relationship: participates_in CCO:I0019503 ! wrn-xrcc5-3 physical interaction relationship: transforms_into CCO:B0013402 ! PARP1_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0013403 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid407 relationship: transforms_into CCO:B0013404 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid413 relationship: transforms_into CCO:B0013405 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid435 relationship: transforms_into CCO:B0013406 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid437 relationship: transforms_into CCO:B0013407 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid444 relationship: transforms_into CCO:B0013408 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid445 relationship: transforms_into CCO:B0013409 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid448 relationship: transforms_into CCO:B0013410 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid456 relationship: transforms_into CCO:B0013411 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid471 relationship: transforms_into CCO:B0013412 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid484 relationship: transforms_into CCO:B0013413 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid488 relationship: transforms_into CCO:B0013414 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid491 relationship: transforms_into CCO:B0013415 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid513 relationship: transforms_into CCO:B0013416 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid514 relationship: transforms_into CCO:B0013417 ! PARP1_HUMAN-PolyADP-ribosyl glutamic acid520 relationship: transforms_into CCO:B0069114 ! PARP1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005468 name: MED28_HUMAN def: "Mediator of RNA polymerase II transcription subunit 28" [UniProtKB:Q9H204] synonym: "Endothelial-derived protein 1" EXACT [UniProtKB:Q9H204] synonym: "Magicin" EXACT [UniProtKB:Q9H204] synonym: "Mediator complex subunit 28" EXACT [UniProtKB:Q9H204] synonym: "Merlin and Grb2-interacting cytoskeletal protein" EXACT [UniProtKB:Q9H204] synonym: "Tumor angiogenesis marker EG-1" EXACT [UniProtKB:Q9H204] xref: EMBL:AAG38612.1 xref: EMBL:AAH11936.1 xref: EMBL:AAK11563.1 xref: EMBL:AAK32724.1 xref: EMBL:AAL26906.1 xref: UniProtKB:Q9BZJ5 xref: UniProtKB:Q9H204 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005071 ! MED28_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006265 ! lck-med28-2 physical interaction relationship: participates_in CCO:I0006790 ! lck-med28-3 phosphorylation relationship: participates_in CCO:I0006828 ! lck-med28-1 physical interaction relationship: participates_in CCO:I0007480 ! fyn-med28-4 physical interaction relationship: participates_in CCO:I0015470 ! med28-ushbp1 physical interaction relationship: participates_in CCO:I0015800 ! magea11-med28 physical interaction relationship: participates_in CCO:I0017810 ! med28-grb2-4 direct interaction relationship: participates_in CCO:I0017811 ! fyn-med28-1 phosphorylation relationship: participates_in CCO:I0017830 ! med28-fyn-1 physical interaction relationship: participates_in CCO:I0017831 ! fyn-med28-2 physical interaction relationship: participates_in CCO:I0017832 ! src-med28-1 physical interaction relationship: participates_in CCO:I0018728 ! fyn-med28-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005469 name: PAK1_HUMAN def: "Serine/threonine-protein kinase PAK 1" [UniProtKB:Q13153] synonym: "Alpha-PAK" EXACT [UniProtKB:Q13153] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13153] synonym: "p21-activated kinase 1" EXACT [UniProtKB:Q13153] synonym: "p65-PAK" EXACT [UniProtKB:Q13153] synonym: "PAK-1" EXACT [UniProtKB:Q13153] xref: EMBL:AAA65441.1 xref: EMBL:AAC24716.1 xref: EMBL:AAC50590.1 xref: EMBL:AAI09300.1 xref: UniProtKB:O75561 xref: UniProtKB:Q13153 xref: UniProtKB:Q13567 xref: UniProtKB:Q32M53 xref: UniProtKB:Q32M54 xref: UniProtKB:Q86W79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005256 ! PAK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006266 ! cdc2l1-pak1-1 physical interaction relationship: participates_in CCO:I0006667 ! cdc2l1-pak1-ac-vit physical interaction relationship: participates_in CCO:I0007946 ! cdc2l1-pak1-2 physical interaction relationship: participates_in CCO:I0018170 ! rac1-pak1-4 direct interaction relationship: participates_in CCO:I0019351 ! rac1-pak1-3 direct interaction relationship: participates_in CCO:I0019383 ! cdc42-pak1-6 physical interaction relationship: participates_in CCO:P0000685 ! ER-nuclear signaling pathway relationship: transforms_into CCO:B0013375 ! PAK1_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0013376 ! PAK1_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0013377 ! PAK1_HUMAN-Phosphothreonine84 relationship: transforms_into CCO:B0013378 ! PAK1_HUMAN-Phosphoserine144 relationship: transforms_into CCO:B0013379 ! PAK1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0013380 ! PAK1_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0013381 ! PAK1_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0013382 ! PAK1_HUMAN-Phosphothreonine212 relationship: transforms_into CCO:B0013383 ! PAK1_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0013384 ! PAK1_HUMAN-Phosphoserine223 relationship: transforms_into CCO:B0013385 ! PAK1_HUMAN-Phosphothreonine225 relationship: transforms_into CCO:B0013386 ! PAK1_HUMAN-Phosphothreonine423 relationship: transforms_into CCO:B0069064 ! PAK1_HUMAN-Phosphothreonine230 [Term] id: CCO:B0005470 name: CENPC_HUMAN def: "Centromere protein C 1" [UniProtKB:Q03188] synonym: "CENP-C" EXACT [UniProtKB:Q03188] synonym: "Centromere autoantigen C" EXACT [UniProtKB:Q03188] synonym: "Interphase centromere complex protein 7" EXACT [UniProtKB:Q03188] xref: EMBL:AAA51974.1 xref: EMBL:AAF73191.1 xref: UniProtKB:Q03188 xref: UniProtKB:Q9P0M5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004323 ! CENPC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006267 ! cenpc1-daxx-1 colocalization relationship: participates_in CCO:I0006946 ! daxx-cenpc1-1 physical interaction relationship: transforms_into CCO:B0011137 ! CENPC_HUMAN-Phosphothreonine167 relationship: transforms_into CCO:B0011138 ! CENPC_HUMAN-Phosphoserine170 relationship: transforms_into CCO:B0011139 ! CENPC_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0011140 ! CENPC_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0011141 ! CENPC_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0011142 ! CENPC_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0011143 ! CENPC_HUMAN-Phosphoserine520 relationship: transforms_into CCO:B0011144 ! CENPC_HUMAN-Phosphoserine524 relationship: transforms_into CCO:B0011145 ! CENPC_HUMAN-Phosphoserine538 relationship: transforms_into CCO:B0064276 ! CENPC_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0064277 ! CENPC_HUMAN-Phosphoserine763 relationship: transforms_into CCO:B0064278 ! CENPC_HUMAN-Phosphoserine773 [Term] id: CCO:B0005471 name: BRAP_HUMAN def: "BRCA1-associated protein" [UniProtKB:Q7Z569] synonym: "BRAP2" EXACT [UniProtKB:Q7Z569] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q7Z569] synonym: "IMP" EXACT [UniProtKB:Q7Z569] synonym: "Impedes mitogenic signal propagation" EXACT [UniProtKB:Q7Z569] synonym: "Renal carcinoma antigen NY-REN-63" EXACT [UniProtKB:Q7Z569] synonym: "RING finger protein 52" EXACT [UniProtKB:Q7Z569] xref: EMBL:AAB88538.1 xref: EMBL:AAC24200.1 xref: EMBL:AAP93638.1 xref: UniProtKB:O43238 xref: UniProtKB:O75341 xref: UniProtKB:Q7Z569 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004185 ! BRAP_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006268 ! brap-hras-2 physical interaction relationship: participates_in CCO:I0006678 ! hras-brap physical interaction relationship: participates_in CCO:I0007523 ! brap-brca1 physical interaction relationship: participates_in CCO:I0007524 ! brca1-brap physical interaction relationship: participates_in CCO:I0007724 ! brap-hras physical interaction relationship: participates_in CCO:I0007839 ! brca1-brap-2 physical interaction relationship: participates_in CCO:I0008527 ! ddb1-brap physical interaction relationship: participates_in CCO:I0016219 ! brap-hras-3 physical interaction relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0010838 ! BRAP_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0063981 ! BRAP_HUMAN-Phosphoserine52 [Term] id: CCO:B0005472 name: SUMO1_HUMAN def: "Small ubiquitin-related modifier 1 precursor" [UniProtKB:P63165] synonym: "GAP-modifying protein 1" EXACT [UniProtKB:P63165] synonym: "GMP1" EXACT [UniProtKB:P63165] synonym: "Sentrin" EXACT [UniProtKB:P63165] synonym: "SMT3 homolog 3" EXACT [UniProtKB:P63165] synonym: "SUMO-1" EXACT [UniProtKB:P63165] synonym: "Ubiquitin-homology domain protein PIC1" EXACT [UniProtKB:P63165] synonym: "Ubiquitin-like protein SMT3C" EXACT [UniProtKB:P63165] synonym: "Ubiquitin-like protein UBL1" EXACT [UniProtKB:P63165] xref: EMBL:AAB39999.1 xref: EMBL:AAB40388.1 xref: EMBL:AAB40390.1 xref: EMBL:AAC50733.1 xref: EMBL:AAC50996.1 xref: EMBL:AAH06462.1 xref: EMBL:AAH53528.1 xref: EMBL:AAH66306.1 xref: EMBL:AAP35278.1 xref: EMBL:AAY24035.1 xref: EMBL:BAB93477.1 xref: EMBL:CAA67898.1 xref: EMBL:CAG46944.1 xref: EMBL:CAG46953.1 xref: UniProtKB:P55856 xref: UniProtKB:P63165 xref: UniProtKB:Q6FGG0 xref: UniProtKB:Q6NZ62 xref: UniProtKB:Q93068 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005704 ! SUMO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006269 ! daxx-ubl_1-1 physical interaction relationship: participates_in CCO:I0006270 ! daxx-mcrs1-1 physical interaction relationship: participates_in CCO:I0006271 ! pml-ubl_1-1 physical interaction relationship: participates_in CCO:I0006630 ! dnmt3b-ubl1-ube2i-1 physical interaction relationship: participates_in CCO:I0015140 ! mgc33948-sumo1 physical interaction relationship: participates_in CCO:I0015691 ! sp100-sumo1 physical interaction relationship: participates_in CCO:I0016139 ! dnmt3b-ubl1-2 physical interaction relationship: participates_in CCO:I0017645 ! dnmt3b-ubl1-3 colocalization relationship: participates_in CCO:I0017956 ! sumo1-uble1a-2 physical interaction relationship: participates_in CCO:I0018255 ! senp2-sumo1-1 direct interaction relationship: participates_in CCO:I0018354 ! dnmt3b-ubl1-1 physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: transforms_into CCO:B0014272 ! SUMO1_HUMAN-Phosphoserine2 [Term] id: CCO:B0005473 name: GTR4_HUMAN def: "Solute carrier family 2, facilitated glucose transporter member 4" [UniProtKB:P14672] synonym: "Glucose transporter type 4, insulin-responsive" EXACT [UniProtKB:P14672] synonym: "GLUT-4" EXACT [UniProtKB:P14672] xref: EMBL:AAA52569.1 xref: EMBL:AAA59189.1 xref: EMBL:AAH69615.1 xref: EMBL:AAH69621.1 xref: EMBL:AAI13593.1 xref: EMBL:AAI26165.1 xref: EMBL:CAA41399.1 xref: UniProtKB:P14672 xref: UniProtKB:Q14CX2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004738 ! SLC2A4_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001577 ! sugar:hydrogen symporter activity relationship: has_function CCO:F0001581 ! glucose transmembrane transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004310 ! substrate-specific transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000050 ! integral to membrane of membrane fraction relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000734 ! vesicle membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0006276 ! daxx-slc2a4-4 physical interaction relationship: participates_in CCO:I0006277 ! daxx-slc2a4-5 physical interaction relationship: participates_in CCO:I0006680 ! slc2a4-daxx-1 physical interaction relationship: participates_in CCO:I0006681 ! daxx-slc2a4-6 physical interaction relationship: participates_in CCO:I0006846 ! daxx-slc2a4-3 physical interaction relationship: participates_in CCO:I0007842 ! daxx-slc2a4-1 physical interaction relationship: participates_in CCO:I0007843 ! daxx-slc2a4-2 physical interaction [Term] id: CCO:B0005474 name: A4_HUMAN def: "Amyloid beta A4 protein precursor" [UniProtKB:P05067] synonym: "ABPP" EXACT [UniProtKB:P05067] synonym: "Alzheimer disease amyloid protein" EXACT [UniProtKB:P05067] synonym: "APP" EXACT [UniProtKB:P05067] synonym: "APPI" EXACT [UniProtKB:P05067] synonym: "Cerebral vascular amyloid peptide" EXACT [UniProtKB:P05067] synonym: "CVAP" EXACT [UniProtKB:P05067] synonym: "PN-II" EXACT [UniProtKB:P05067] synonym: "PreA4" EXACT [UniProtKB:P05067] synonym: "Protease nexin-II" EXACT [UniProtKB:P05067] xref: EMBL:AAA35540.1 xref: EMBL:AAA51564.1 xref: EMBL:AAA51722.1 xref: EMBL:AAA51726.1 xref: EMBL:AAA51727.1 xref: EMBL:AAA51768.1 xref: EMBL:AAA58727.1 xref: EMBL:AAA60163.1 xref: EMBL:AAB23646.1 xref: EMBL:AAB26263.2 xref: EMBL:AAB26264.2 xref: EMBL:AAB26265.2 xref: EMBL:AAB59501.1 xref: EMBL:AAB59502.1 xref: EMBL:AAC13654.1 xref: EMBL:AAC60601.2 xref: EMBL:AAH04369.1 xref: EMBL:AAH65529.1 xref: EMBL:AAQ14327.1 xref: EMBL:AAW82435.1 xref: EMBL:BAA22264.1 xref: EMBL:BAB71958.2 xref: EMBL:CAA30041.1 xref: EMBL:CAA30042.1 xref: EMBL:CAA30050.1 xref: EMBL:CAA31830.1 xref: EMBL:CAA68374.1 xref: EMBL:EAX09958.1 xref: UniProtKB:P05067 xref: UniProtKB:P09000 xref: UniProtKB:P78438 xref: UniProtKB:Q13764 xref: UniProtKB:Q13778 xref: UniProtKB:Q13793 xref: UniProtKB:Q16011 xref: UniProtKB:Q16014 xref: UniProtKB:Q16019 xref: UniProtKB:Q16020 xref: UniProtKB:Q6GSC0 xref: UniProtKB:Q8WZ99 xref: UniProtKB:Q9BT38 xref: UniProtKB:Q9UC33 xref: UniProtKB:Q9UCA9 xref: UniProtKB:Q9UCB6 xref: UniProtKB:Q9UCC8 xref: UniProtKB:Q9UCD1 xref: UniProtKB:Q9UQ58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004007 ! APP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006279 ! app-apbb1-2 physical interaction relationship: participates_in CCO:I0006333 ! tgfb1-bapp-1 physical interaction relationship: participates_in CCO:I0006334 ! tgfb2-bapp-5 physical interaction relationship: participates_in CCO:I0006335 ! sch1-app-3 physical interaction relationship: participates_in CCO:I0006541 ! shc1-app-2 physical interaction relationship: participates_in CCO:I0006542 ! shc1-app-1 physical interaction relationship: participates_in CCO:I0006629 ! sch1-app-2 physical interaction relationship: participates_in CCO:I0006668 ! app-tp53bp2-2 physical interaction relationship: participates_in CCO:I0006669 ! apbb2-app-2 physical interaction relationship: participates_in CCO:I0006986 ! tgfb2-bapp-2 physical interaction relationship: participates_in CCO:I0006987 ! tgfb2-bapp-3 physical interaction relationship: participates_in CCO:I0006992 ! apbb2 -app-1 physical interaction relationship: participates_in CCO:I0007061 ! apbb1-app physical interaction relationship: participates_in CCO:I0007284 ! app-tp53bp2-1 physical interaction relationship: participates_in CCO:I0007285 ! app-tp53bp2-3 physical interaction relationship: participates_in CCO:I0007390 ! sch1-app-4 physical interaction relationship: participates_in CCO:I0007411 ! app-apbb1-6 physical interaction relationship: participates_in CCO:I0007448 ! tgfb2-bapp-1 physical interaction relationship: participates_in CCO:I0007585 ! tgfb2-bapp-4 physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0007727 ! app-apbb1-5 physical interaction relationship: participates_in CCO:I0007784 ! tgfb1-tgfb2-bapp-2 physical interaction relationship: participates_in CCO:I0015960 ! app-apoa-5 physical interaction relationship: participates_in CCO:I0016124 ! app-apoa1-1 physical interaction relationship: participates_in CCO:I0016220 ! app-apb1-1 physical interaction relationship: participates_in CCO:I0016311 ! app-apoa1-3 physical interaction relationship: participates_in CCO:I0017493 ! app-hadh2-1 physical interaction relationship: participates_in CCO:I0017644 ! hadh2-app-2 physical interaction relationship: participates_in CCO:I0017903 ! app-chrna7-1 colocalization relationship: participates_in CCO:I0018080 ! app-chrna7-3 physical interaction relationship: participates_in CCO:I0018133 ! app-apbb3 physical interaction relationship: participates_in CCO:I0018136 ! app-hadh2-2 physical interaction relationship: participates_in CCO:I0018208 ! mapk8ip1-app-2 physical interaction relationship: participates_in CCO:I0018526 ! mapk8ip1-app-4 direct interaction relationship: participates_in CCO:I0018569 ! hadh2-app-1 physical interaction relationship: participates_in CCO:I0018573 ! mapk8ip1-app-1 physical interaction relationship: participates_in CCO:I0018622 ! app-nsf-3 physical interaction relationship: participates_in CCO:I0018674 ! app-apoa1-2 physical interaction relationship: participates_in CCO:I0018855 ! mapk8ip1-app-3 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:I0019223 ! app-apba1-1 physical interaction relationship: participates_in CCO:I0019224 ! apba1-app-1 physical interaction relationship: participates_in CCO:I0019267 ! app-apoa-6 physical interaction relationship: participates_in CCO:I0019303 ! app-app colocalization relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: transforms_into CCO:B0010382 ! A4_HUMAN-Phosphoserine198 relationship: transforms_into CCO:B0010383 ! A4_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0010384 ! A4_HUMAN-Phosphothreonine729 relationship: transforms_into CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: transforms_into CCO:B0010386 ! A4_HUMAN-Phosphothreonine743 relationship: transforms_into CCO:B0010387 ! A4_HUMAN-Phosphotyrosine757 relationship: transforms_into CCO:B0065228 ! A4_HUMAN-Phosphotyrosine762 [Term] id: CCO:B0005475 name: MED9_HUMAN def: "Mediator of RNA polymerase II transcription subunit 9" [UniProtKB:Q9NWA0] synonym: "Mediator complex subunit 9" EXACT [UniProtKB:Q9NWA0] xref: EMBL:AAI04989.1 xref: EMBL:AAI12030.1 xref: EMBL:BAA91483.1 xref: EMBL:EAW55706.1 xref: UniProtKB:Q9NWA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005079 ! MED9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016032 ! q9nwa0-vdrip-4 physical interaction relationship: participates_in CCO:I0016033 ! q9nwa0-vdrip-5 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016235 ! q9nwa0-vdrip-3 physical interaction relationship: participates_in CCO:I0017350 ! q9nwa0-vdrip-1 physical interaction relationship: participates_in CCO:I0017850 ! q9nwa0-vdrip-2 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005476 name: SH22A_HUMAN def: "SH2 domain-containing protein 2A" [UniProtKB:Q9NP31] synonym: "SH2 domain-containing adapter protein" EXACT [UniProtKB:Q9NP31] synonym: "T cell-specific adapter protein" EXACT [UniProtKB:Q9NP31] synonym: "TSAd" EXACT [UniProtKB:Q9NP31] synonym: "VEGF receptor-associated protein" EXACT [UniProtKB:Q9NP31] xref: EMBL:AAC99298.1 xref: EMBL:AAF43260.1 xref: EMBL:AAF69027.1 xref: EMBL:AAH12107.1 xref: EMBL:BAD96457.1 xref: EMBL:CAA04185.1 xref: EMBL:CAH70007.1 xref: EMBL:CAI16337.1 xref: UniProtKB:O43817 xref: UniProtKB:Q5VZS5 xref: UniProtKB:Q9NP31 xref: UniProtKB:Q9UPA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005605 ! SH2D2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006283 ! lck-lad-3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0014049 ! SH22A_HUMAN-Phosphotyrosine39 relationship: transforms_into CCO:B0014050 ! SH22A_HUMAN-Phosphotyrosine216 relationship: transforms_into CCO:B0014051 ! SH22A_HUMAN-Phosphotyrosine305 relationship: transforms_into CCO:B0070458 ! SH22A_HUMAN-Phosphoserine217 relationship: transforms_into CCO:B0070459 ! SH22A_HUMAN-Phosphoserine296 [Term] id: CCO:B0005477 name: TRIB3_HUMAN def: "Tribbles homolog 3" [UniProtKB:Q96RU7] synonym: "Neuronal cell death-inducible putative kinase" EXACT [UniProtKB:Q96RU7] synonym: "p65-interacting inhibitor of NF-kappa-B" EXACT [UniProtKB:Q96RU7] synonym: "SINK" EXACT [UniProtKB:Q96RU7] synonym: "TRB-3" EXACT [UniProtKB:Q96RU7] xref: EMBL:AAH19363.1 xref: EMBL:AAH27484.1 xref: EMBL:AAK58175.1 xref: EMBL:AAP04407.1 xref: EMBL:BAB15597.1 xref: EMBL:BAD96557.1 xref: EMBL:CAB81634.1 xref: EMBL:CAG27047.1 xref: EMBL:CAG33647.1 xref: UniProtKB:Q53GU4 xref: UniProtKB:Q53ZW7 xref: UniProtKB:Q6I9Y9 xref: UniProtKB:Q8TAI6 xref: UniProtKB:Q96RU7 xref: UniProtKB:Q9H5M8 xref: UniProtKB:Q9NUD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005833 ! TRIB3_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006284 ! trib3-atf5-1 physical interaction relationship: participates_in CCO:I0007736 ! trib3-map2k1-2 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0016248 ! trib3-atf4-3 physical interaction relationship: participates_in CCO:I0018007 ! trib3-atf4-4 physical interaction relationship: participates_in CCO:I0019244 ! trib3-map2k7-1 physical interaction relationship: participates_in CCO:I0019571 ! trib3-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019572 ! trib3-eef1g physical interaction relationship: participates_in CCO:I0019573 ! trib3-htatip physical interaction relationship: participates_in CCO:I0019674 ! trib3-cops6 physical interaction relationship: participates_in CCO:I0019675 ! trib3-gdf9 physical interaction relationship: participates_in CCO:I0019676 ! trib3-git1 physical interaction relationship: participates_in CCO:I0019677 ! trib3-setdb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005478 name: INSR_HUMAN def: "Insulin receptor precursor" [UniProtKB:P06213] synonym: "CD220 antigen" EXACT [UniProtKB:P06213] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P06213] synonym: "IR" EXACT [UniProtKB:P06213] xref: EMBL:AAA59174.1 xref: EMBL:AAA59175.1 xref: EMBL:AAA59176.1 xref: EMBL:AAA59177.1 xref: EMBL:AAA59178.1 xref: EMBL:AAA59190.1 xref: EMBL:AAA59452.1 xref: EMBL:AAA86791.1 xref: EMBL:AAC37604.1 xref: EMBL:CAA26096.1 xref: UniProtKB:P06213 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004900 ! INSR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006286 ! insr-shc1-1 physical interaction relationship: participates_in CCO:I0016257 ! insr-ywhab-2 physical interaction relationship: participates_in CCO:I0018176 ! insr-irs1-1 physical interaction relationship: participates_in CCO:I0018177 ! insr-irs1-2 physical interaction relationship: participates_in CCO:I0018605 ! insr-crkl-1 physical interaction relationship: participates_in CCO:I0018608 ! insr-crkl-2 physical interaction relationship: participates_in CCO:I0019255 ! insr-sorbs-1 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0001644 ! regulation of gene-specific transcription relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002569 ! positive regulation of glycolysis relationship: transforms_into CCO:B0012419 ! INSR_HUMAN-Phosphotyrosine992 relationship: transforms_into CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: transforms_into CCO:B0012421 ! INSR_HUMAN-Phosphotyrosine1011 relationship: transforms_into CCO:B0012422 ! INSR_HUMAN-Phosphotyrosine1185 relationship: transforms_into CCO:B0012423 ! INSR_HUMAN-Phosphotyrosine1189 relationship: transforms_into CCO:B0012424 ! INSR_HUMAN-Phosphotyrosine1190 relationship: transforms_into CCO:B0012425 ! INSR_HUMAN-Phosphotyrosine1355 relationship: transforms_into CCO:B0012426 ! INSR_HUMAN-Phosphotyrosine1361 [Term] id: CCO:B0005479 name: TNR6_HUMAN def: "Tumor necrosis factor receptor superfamily member 6 precursor" [UniProtKB:P25445] synonym: "Apo-1 antigen" EXACT [UniProtKB:P25445] synonym: "Apoptosis-mediating surface antigen FAS" EXACT [UniProtKB:P25445] synonym: "CD95 antigen" EXACT [UniProtKB:P25445] synonym: "FASLG receptor" EXACT [UniProtKB:P25445] xref: EMBL:AAA63174.1 xref: EMBL:AAH12479.1 xref: EMBL:AAR08906.1 xref: EMBL:CAA45250.1 xref: EMBL:CAA61473.1 xref: EMBL:CAA88031.1 xref: EMBL:CAA88032.1 xref: EMBL:CAA88033.1 xref: EMBL:CAA94430.1 xref: EMBL:CAA94431.1 xref: UniProtKB:P25445 xref: UniProtKB:Q14292 xref: UniProtKB:Q14293 xref: UniProtKB:Q14294 xref: UniProtKB:Q14295 xref: UniProtKB:Q16652 xref: UniProtKB:Q6SSE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005805 ! FAS_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006287 ! cam-cd95-1 physical interaction relationship: participates_in CCO:I0006288 ! cam-cd95pm physical interaction relationship: participates_in CCO:I0007344 ! cam-cd95 physical interaction relationship: participates_in CCO:I0007543 ! cam-cd95-2 physical interaction relationship: participates_in CCO:I0008341 ! tnfrsf6-rif1 physical interaction relationship: participates_in CCO:I0015920 ! tnfrsf6-fadd-1 physical interaction relationship: participates_in CCO:I0016251 ! tnfrsf6-fadd-6 physical interaction relationship: participates_in CCO:I0016254 ! tnfsf6-tnfrsf6-2 physical interaction relationship: participates_in CCO:I0017358 ! fadd-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0017690 ! tnfrsf6-fadd-14 physical interaction relationship: participates_in CCO:I0017692 ! tnfrsf6-fadd-10 physical interaction relationship: participates_in CCO:I0017863 ! tnfrsf6-fadd-2 physical interaction relationship: participates_in CCO:I0017865 ! tnfrsf6-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0017866 ! tnfrsf6-fadd-5 physical interaction relationship: participates_in CCO:I0017867 ! tnfsf6-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0018016 ! tnfrsf6-fadd-12 physical interaction relationship: participates_in CCO:I0018017 ! tnfrsf6-fadd-13 physical interaction relationship: participates_in CCO:I0018018 ! tnfrsf6-tnfrsf6-2 physical interaction relationship: participates_in CCO:I0018019 ! tnsfrsf6-ripk1-1 physical interaction relationship: participates_in CCO:I0018783 ! tnfrsf6-fadd-8 physical interaction relationship: participates_in CCO:I0018784 ! tnfrsf6-fadd-9 physical interaction relationship: participates_in CCO:I0019636 ! tnfrsf6-crmp1 physical interaction relationship: participates_in CCO:I0019865 ! tnfrsf6-eef1a1 physical interaction relationship: participates_in CCO:I0020483 ! tnfrsf6-c14orf1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0005480 name: 1433B_HUMAN def: "14-3-3 protein beta/alpha" [UniProtKB:P31946] synonym: "KCIP-1" EXACT [UniProtKB:P31946] synonym: "Protein 1054" EXACT [UniProtKB:P31946] synonym: "Protein kinase C inhibitor protein 1" EXACT [UniProtKB:P31946] xref: EMBL:AAH01359.1 xref: EMBL:CAA15497.1 xref: EMBL:CAA40621.1 xref: UniProtKB:P31946 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003992 ! YWHAB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006289 ! igf1r-ywhab-1 physical interaction relationship: participates_in CCO:I0006307 ! abl1-ywhab-1 physical interaction relationship: participates_in CCO:I0007742 ! cdn1b-ywhab-1 physical interaction relationship: participates_in CCO:I0015976 ! bcl2l11-ywhab-2 phosphorylation relationship: participates_in CCO:I0016257 ! insr-ywhab-2 physical interaction relationship: participates_in CCO:I0016272 ! raf1-ywhab-1 physical interaction relationship: participates_in CCO:I0017232 ! map3k3-ywhab physical interaction relationship: participates_in CCO:I0017681 ! raf1-ywhab-3 physical interaction relationship: participates_in CCO:I0017688 ! raf1-ywhab-4 physical interaction relationship: participates_in CCO:I0018500 ! braf-ywhab physical interaction relationship: participates_in CCO:I0019251 ! raf1-ywhab physical interaction relationship: participates_in CCO:I0019376 ! raf1-ywhab-2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: transforms_into CCO:B0010364 ! 1433B_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0010365 ! 1433B_HUMAN-Phosphoserine186 [Term] id: CCO:B0005481 name: TBP_HUMAN def: "TATA-box-binding protein" [UniProtKB:P20226] synonym: "TATA sequence-binding protein" EXACT [UniProtKB:P20226] synonym: "TATA-binding factor" EXACT [UniProtKB:P20226] synonym: "TATA-box factor" EXACT [UniProtKB:P20226] synonym: "Transcription initiation factor TFIID TBP subunit" EXACT [UniProtKB:P20226] xref: EMBL:AAA36731.1 xref: EMBL:AAC03409.1 xref: EMBL:CAA20286.1 xref: EMBL:CAA38736.1 xref: UniProtKB:P20226 xref: UniProtKB:Q16845 xref: UniProtKB:Q9UC02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005744 ! TBP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:I0006298 ! tbp-taf1-2 physical interaction relationship: participates_in CCO:I0006698 ! tp53-tbp1 physical interaction relationship: participates_in CCO:I0006699 ! tp53-tbp-2 physical interaction relationship: participates_in CCO:I0006714 ! tbp-taf1-1 physical interaction relationship: participates_in CCO:I0007070 ! mdm2-tbp-1 physical interaction relationship: participates_in CCO:I0007734 ! taf1l-tbp-1 physical interaction relationship: participates_in CCO:I0016401 ! nfkbib-tbp physical interaction relationship: participates_in CCO:I0017591 ! fate1-tbp physical interaction relationship: participates_in CCO:I0018140 ! gtf2a1-tbp-1 physical interaction relationship: participates_in CCO:I0018141 ! gtf2b-tbp-1 physical interaction relationship: participates_in CCO:I0018142 ! hmgb1-tbp-1 physical interaction relationship: participates_in CCO:I0018343 ! tbp-edf1-1 physical interaction relationship: participates_in CCO:I0019170 ! tbp-brf1 physical interaction relationship: participates_in CCO:I0019171 ! tbp-cxxc1 physical interaction relationship: participates_in CCO:I0019172 ! tbp-emid2 physical interaction relationship: participates_in CCO:I0019173 ! tbp-hap1 physical interaction relationship: participates_in CCO:I0019931 ! c19orf14-tbp physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005482 name: DAPK1_HUMAN def: "Death-associated protein kinase 1" [UniProtKB:P53355] synonym: "DAP kinase 1" EXACT [UniProtKB:P53355] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P53355] xref: EMBL:AAI13661.1 xref: EMBL:AAP35581.1 xref: EMBL:CAA53712.1 xref: EMBL:CAH18690.1 xref: UniProtKB:P53355 xref: UniProtKB:Q14CQ7 xref: UniProtKB:Q68CP8 xref: UniProtKB:Q9BTL8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004435 ! DAPK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006299 ! dapk-erk physical interaction relationship: participates_in CCO:I0006300 ! dapk-erk-3 physical interaction relationship: participates_in CCO:I0007551 ! dapk-erk-2 physical interaction relationship: participates_in CCO:I0007858 ! dapk-erk-1 physical interaction relationship: transforms_into CCO:B0011427 ! DAPK1_HUMAN-Phosphoserine308 [Term] id: CCO:B0005483 name: STAU1_HUMAN def: "Double-stranded RNA-binding protein Staufen homolog 1" [UniProtKB:O95793] xref: EMBL:AAD17530.1 xref: EMBL:AAD17531.1 xref: EMBL:AAD17532.1 xref: EMBL:AAD17533.1 xref: EMBL:AAH50432.1 xref: EMBL:AAH95397.1 xref: EMBL:CAB40082.1 xref: EMBL:CAB66536.1 xref: EMBL:CAC14084.1 xref: EMBL:CAC14085.1 xref: UniProtKB:O95793 xref: UniProtKB:Q6GTM4 xref: UniProtKB:Q9H5B4 xref: UniProtKB:Q9H5B5 xref: UniProtKB:Q9Y3Q2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005688 ! STAU1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000372 ! rough endoplasmic reticulum relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0006301 ! rent1-stau-2 physical interaction relationship: participates_in CCO:I0006715 ! rent1-stau-3 physical interaction relationship: participates_in CCO:I0006716 ! rent1-stau-4 physical interaction relationship: participates_in CCO:I0006848 ! stau-loc84643-1 physical interaction relationship: participates_in CCO:I0007552 ! rent1-stau-1 physical interaction relationship: participates_in CCO:I0007844 ! stau-dhx9-1 physical interaction [Term] id: CCO:B0005484 name: HDAC1_HUMAN def: "Histone deacetylase 1" [UniProtKB:Q13547] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q13547] synonym: "HD1" EXACT [UniProtKB:Q13547] xref: EMBL:AAC50475.1 xref: EMBL:AAH00301.1 xref: EMBL:BAA08909.1 xref: UniProtKB:Q13547 xref: UniProtKB:Q92534 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004786 ! HDAC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006302 ! hcfc1-hdac1-1 physical interaction relationship: participates_in CCO:I0006564 ! tp53-nfya-3 physical interaction relationship: participates_in CCO:I0006565 ! tp53-nfya-4 physical interaction relationship: participates_in CCO:I0006795 ! tp53-hdac1 physical interaction relationship: participates_in CCO:I0006821 ! brms1-hdac1 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007150 ! cbp-atf3 physical interaction relationship: participates_in CCO:I0007189 ! hdac1-brms1 physical interaction relationship: participates_in CCO:I0007309 ! rb1-hdac1 physical interaction relationship: participates_in CCO:I0007460 ! suv39h1-hdac1-3 physical interaction relationship: participates_in CCO:I0007496 ! rb1-e2f1 physical interaction relationship: participates_in CCO:I0007869 ! hdac1-rbbp4-1 physical interaction relationship: participates_in CCO:I0007975 ! suv93h1-hdac1-1 physical interaction relationship: participates_in CCO:I0007976 ! suv93h1-hdac1-2 physical interaction relationship: participates_in CCO:I0008444 ! tpd52l1-hdac1 physical interaction relationship: participates_in CCO:I0016122 ! sap18-hdac1-2 physical interaction relationship: participates_in CCO:I0016142 ! hdac1-nfkb1-7 direct interaction relationship: participates_in CCO:I0016143 ! hdac1-rela direct interaction relationship: participates_in CCO:I0016144 ! hdac1-nfkb1-8 direct interaction relationship: participates_in CCO:I0016145 ! hdac1-rela-4 direct interaction relationship: participates_in CCO:I0017391 ! hdac1-dnmt3l direct interaction relationship: participates_in CCO:I0017392 ! hdac1-dnmt3l-1 direct interaction relationship: participates_in CCO:I0017412 ! setdb1-dnmt3a-3 physical interaction relationship: participates_in CCO:I0017659 ! ncor2-hdac1-1 physical interaction relationship: participates_in CCO:I0017660 ! hdac1-hdac2-1 physical interaction relationship: participates_in CCO:I0017908 ! dnmt3l-hdac1 physical interaction relationship: participates_in CCO:I0018538 ! hdac1-rcor1 physical interaction relationship: participates_in CCO:I0018539 ! hdac1-smarce1 physical interaction relationship: participates_in CCO:I0018540 ! hdac1-smarca4 physical interaction relationship: participates_in CCO:I0018541 ! hdac1-smarcc2 physical interaction relationship: participates_in CCO:I0018699 ! mbd1-hdac1-3 physical interaction relationship: participates_in CCO:I0018701 ! morf4l2-hdac1-1 physical interaction relationship: participates_in CCO:I0018729 ! eed-hdac1 physical interaction relationship: participates_in CCO:I0018833 ! cir-hdac1-1 colocalization relationship: participates_in CCO:I0018869 ! hdac1-nfkb1 physical interaction relationship: participates_in CCO:I0018870 ! hdac1-nfkb1-1 physical interaction relationship: participates_in CCO:I0018871 ! hdac1-rela-2 physical interaction relationship: participates_in CCO:I0018872 ! hdac1-rela-3 physical interaction relationship: participates_in CCO:I0019385 ! hdac1-rbbp7-1 physical interaction relationship: participates_in CCO:I0019386 ! hdac1-hdac1-1 physical interaction relationship: participates_in CCO:I0019387 ! hdac1-hdac2-2 physical interaction relationship: participates_in CCO:I0019446 ! hdac1-rfx1 physical interaction relationship: participates_in CCO:I0019498 ! sap18-hdac1-1 physical interaction relationship: participates_in CCO:I0019522 ! mbde-hdac1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0012155 ! HDAC1_HUMAN-Phosphotyrosine221 relationship: transforms_into CCO:B0012156 ! HDAC1_HUMAN-Phosphoserine393 relationship: transforms_into CCO:B0012157 ! HDAC1_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0012158 ! HDAC1_HUMAN-Phosphoserine423 [Term] id: CCO:B0005485 name: SP1_HUMAN def: "Transcription factor Sp1" [UniProtKB:P08047] xref: EMBL:AAA61154.1 xref: EMBL:AAF67726.1 xref: EMBL:AAF78781.1 xref: EMBL:AAH43224.1 xref: EMBL:AAH62539.1 xref: EMBL:BAB13476.1 xref: EMBL:CAB75345.1 xref: UniProtKB:P08047 xref: UniProtKB:Q86TN8 xref: UniProtKB:Q9H3Q5 xref: UniProtKB:Q9NR51 xref: UniProtKB:Q9NY21 xref: UniProtKB:Q9NYE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005651 ! SP1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006304 ! hcfc1-sp1-1 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007355 ! hcfc1-many-2 physical interaction relationship: participates_in CCO:I0018216 ! sp1-sp1-1 physical interaction relationship: participates_in CCO:I0018579 ! mapk11-sp1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002565 ! positive regulation of transcription from RNA polymerase II promoter, global relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014156 ! SP1_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0014157 ! SP1_HUMAN-Phosphoserine59 [Term] id: CCO:B0005486 name: HRX_HUMAN def: "Histone-lysine N-methyltransferase HRX" [UniProtKB:Q03164] synonym: "ALL-1" EXACT [UniProtKB:Q03164] synonym: "CXXC-type zinc finger protein 7" EXACT [UniProtKB:Q03164] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q03164] synonym: "Lysine N-methyltransferase 2A" EXACT [UniProtKB:Q03164] synonym: "Trithorax-like protein" EXACT [UniProtKB:Q03164] synonym: "Zinc finger protein HRX" EXACT [UniProtKB:Q03164] xref: EMBL:AAA18644.1 xref: EMBL:AAA58669.1 xref: EMBL:AAA92511.1 xref: EMBL:AAB28545.1 xref: EMBL:AAB34770.1 xref: EMBL:AAG26332.2 xref: EMBL:AAQ63624.1 xref: EMBL:BAA03407.1 xref: EMBL:CAA58584.1 xref: EMBL:CAA93625.1 xref: UniProtKB:Q03164 xref: UniProtKB:Q13743 xref: UniProtKB:Q13744 xref: UniProtKB:Q14845 xref: UniProtKB:Q16364 xref: UniProtKB:Q6UBD1 xref: UniProtKB:Q9UMA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004829 ! MLL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006305 ! mll-hcfc2-2 physical interaction relationship: participates_in CCO:I0008569 ! mll-hcfc2-1 physical interaction relationship: participates_in CCO:I0016277 ! ppie-mll-2 physical interaction relationship: participates_in CCO:I0017510 ! mll-mll-2 physical interaction relationship: participates_in CCO:I0017878 ! mll-mll-1 physical interaction relationship: participates_in CCO:I0018192 ! ppie-cyp33-1 physical interaction relationship: participates_in CCO:I0018411 ! all1-all1 direct interaction relationship: participates_in CCO:I0018763 ! all1-all1-1 direct interaction relationship: participates_in CCO:I0019336 ! all1-all1-2 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012255 ! HRX_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0012256 ! HRX_HUMAN-Phosphothreonine337 relationship: transforms_into CCO:B0012257 ! HRX_HUMAN-Phosphoserine1837 relationship: transforms_into CCO:B0012258 ! HRX_HUMAN-Phosphoserine2151 relationship: transforms_into CCO:B0012259 ! HRX_HUMAN-Phosphoserine2866 relationship: transforms_into CCO:B0012260 ! HRX_HUMAN-Phosphothreonine2940 relationship: transforms_into CCO:B0012261 ! HRX_HUMAN-Phosphoserine3036 relationship: transforms_into CCO:B0012262 ! HRX_HUMAN-Phosphoserine3511 relationship: transforms_into CCO:B0048280 ! HRX_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0048281 ! HRX_HUMAN-Phosphothreonine1845 relationship: transforms_into CCO:B0066897 ! HRX_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0066898 ! HRX_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0066899 ! HRX_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0066900 ! HRX_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0066901 ! HRX_HUMAN-Phosphothreonine506 relationship: transforms_into CCO:B0066902 ! HRX_HUMAN-Phosphoserine680 relationship: transforms_into CCO:B0066903 ! HRX_HUMAN-Phosphoserine831 relationship: transforms_into CCO:B0066904 ! HRX_HUMAN-Phosphothreonine840 relationship: transforms_into CCO:B0066905 ! HRX_HUMAN-Phosphoserine1056 relationship: transforms_into CCO:B0066906 ! HRX_HUMAN-Phosphothreonine1839 relationship: transforms_into CCO:B0066907 ! HRX_HUMAN-Phosphoserine2098 relationship: transforms_into CCO:B0066908 ! HRX_HUMAN-Phosphothreonine2147 relationship: transforms_into CCO:B0066909 ! HRX_HUMAN-Phosphothreonine2525 relationship: transforms_into CCO:B0066910 ! HRX_HUMAN-Phosphoserine2955 relationship: transforms_into CCO:B0066911 ! HRX_HUMAN-Phosphothreonine3372 relationship: transforms_into CCO:B0066912 ! HRX_HUMAN-Phosphoserine3518 [Term] id: CCO:B0005487 name: SFRS1_HUMAN def: "Splicing factor, arginine/serine-rich 1" [UniProtKB:Q07955] synonym: "Alternative-splicing factor 1" EXACT [UniProtKB:Q07955] synonym: "ASF-1" EXACT [UniProtKB:Q07955] synonym: "pre-mRNA-splicing factor SF2, P33 subunit" EXACT [UniProtKB:Q07955] xref: EMBL:AAA03476.1 xref: EMBL:AAA35564.1 xref: EMBL:AAA35565.1 xref: EMBL:AAH10264.1 xref: EMBL:AAH33785.1 xref: EMBL:BAB93456.1 xref: UniProtKB:Q07955 xref: UniProtKB:Q13809 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005600 ! SFRS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006306 ! srpk1-sfrs1-1 physical interaction relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0006847 ! cbfa-cbfb-1 physical interaction relationship: participates_in CCO:I0006952 ! cbfa-cbfb physical interaction relationship: participates_in CCO:I0007100 ! srpk1-sfrs1-2 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0016283 ! cir-sfrs1-1 physical interaction relationship: participates_in CCO:I0017982 ! cbfb-p32-1 physical interaction relationship: participates_in CCO:I0017983 ! cbfb-p32-2 physical interaction relationship: participates_in CCO:I0018589 ! cbfb-p32-3 colocalization relationship: participates_in CCO:I0018657 ! cir-sfrs1-3 physical interaction relationship: participates_in CCO:I0018660 ! cir-sfrs1-2 physical interaction relationship: transforms_into CCO:B0014031 ! SFRS1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0014032 ! SFRS1_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0014033 ! SFRS1_HUMAN-Omega-N-methylarginine93 relationship: transforms_into CCO:B0014034 ! SFRS1_HUMAN-Omega-N-methylated arginine97 relationship: transforms_into CCO:B0014035 ! SFRS1_HUMAN-Omega-N-methylarginine109 relationship: transforms_into CCO:B0014036 ! SFRS1_HUMAN-Phosphotyrosine189 relationship: transforms_into CCO:B0014037 ! SFRS1_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0014038 ! SFRS1_HUMAN-Phosphoserine201 relationship: transforms_into CCO:B0014039 ! SFRS1_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0014040 ! SFRS1_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0014041 ! SFRS1_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0070414 ! SFRS1_HUMAN-Phosphotyrosine202 relationship: transforms_into CCO:B0070415 ! SFRS1_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0070416 ! SFRS1_HUMAN-Phosphotyrosine237 [Term] id: CCO:B0005488 name: 1433E_HUMAN def: "14-3-3 protein epsilon" [UniProtKB:P62258] synonym: "14-3-3E" EXACT [UniProtKB:P62258] xref: EMBL:AAA75301.1 xref: EMBL:AAC50175.1 xref: EMBL:AAC50625.1 xref: EMBL:AAC50710.1 xref: EMBL:AAD00026.1 xref: EMBL:AAH00179.1 xref: EMBL:AAH01440.1 xref: EMBL:AAP35825.1 xref: EMBL:BAA32538.1 xref: EMBL:EAW90628.1 xref: UniProtKB:P29360 xref: UniProtKB:P42655 xref: UniProtKB:P62258 xref: UniProtKB:Q53XZ5 xref: UniProtKB:Q63631 xref: UniProtKB:Q7M4R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003993 ! YWHAE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006307 ! abl1-ywhab-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007180 ! snf1lk-ywhaz-1 physical interaction relationship: participates_in CCO:I0007743 ! cdn1b-ywhae-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0015224 ! kiaa0514-ywhae physical interaction relationship: participates_in CCO:I0015507 ! grap2-ywhae physical interaction relationship: participates_in CCO:I0016591 ! map3k1-ywhae physical interaction relationship: participates_in CCO:I0016936 ! q9nyj8-ywhae physical interaction relationship: participates_in CCO:I0017233 ! map3k3-ywhae physical interaction relationship: participates_in CCO:I0017357 ! map3k5-ywhae-1 physical interaction relationship: participates_in CCO:I0017475 ! disc1-ywhae physical interaction relationship: participates_in CCO:I0017476 ! disc1-ywhae-1 physical interaction relationship: participates_in CCO:I0018268 ! qsk-ywhaz-1 physical interaction relationship: participates_in CCO:I0018270 ! mark1-ywhaz-1 physical interaction relationship: participates_in CCO:I0018271 ! mark2-ywhaz-2 physical interaction relationship: participates_in CCO:I0018272 ! mark3-ywhaz-1 physical interaction relationship: participates_in CCO:I0018273 ! mark4-ywhaz-3 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0010366 ! 1433E_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0010367 ! 1433E_HUMAN-Phosphoserine210 [Term] id: CCO:B0005489 name: 1433G_HUMAN def: "14-3-3 protein gamma" [UniProtKB:P61981] synonym: "KCIP-1" EXACT [UniProtKB:P61981] synonym: "Protein kinase C inhibitor protein 1" EXACT [UniProtKB:P61981] xref: EMBL:AAD48408.1 xref: EMBL:AAH20963.1 xref: EMBL:BAA85184.1 xref: EMBL:CAG46702.1 xref: EMBL:CAG46723.1 xref: UniProtKB:O70457 xref: UniProtKB:P35214 xref: UniProtKB:P61981 xref: UniProtKB:Q6FH52 xref: UniProtKB:Q9UDP2 xref: UniProtKB:Q9UN99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003995 ! YWHAG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006307 ! abl1-ywhab-1 physical interaction relationship: participates_in CCO:I0007744 ! cdn1b-ywhag-1 physical interaction relationship: participates_in CCO:I0017235 ! map3k3-ywhag physical interaction relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation relationship: participates_in CCO:P0002784 ! regulation of synaptic plasticity relationship: transforms_into CCO:B0010369 ! 1433G_HUMAN-N-acetylvaline2 relationship: transforms_into CCO:B0031285 ! 1433G_HUMAN-Phosphotyrosine117 relationship: transforms_into CCO:B0048149 ! 1433G_HUMAN-Phosphothreonine145 relationship: transforms_into CCO:B0065193 ! 1433G_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005490 name: 1433F_HUMAN def: "14-3-3 protein eta" [UniProtKB:Q04917] synonym: "Protein AS1" EXACT [UniProtKB:Q04917] xref: EMBL:AAA35483.1 xref: EMBL:AAB36036.1 xref: EMBL:AAH03047.1 xref: EMBL:BAA11418.1 xref: EMBL:CAA40620.1 xref: EMBL:CAA55017.1 xref: EMBL:CAA56676.1 xref: EMBL:CAB05112.1 xref: EMBL:CAG30498.1 xref: UniProtKB:Q04917 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003994 ! YWHAH_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005587 ! glucocorticoid receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006307 ! abl1-ywhab-1 physical interaction relationship: participates_in CCO:I0007213 ! pard6a-ywhah-1 physical interaction relationship: participates_in CCO:I0007215 ! pard6b-ywhah-1 physical interaction relationship: participates_in CCO:I0007219 ! ywhah-pard3-1 physical interaction relationship: participates_in CCO:I0007220 ! pard3-ywhah-1 physical interaction relationship: participates_in CCO:I0007269 ! nek1-ywhah-1 physical interaction relationship: participates_in CCO:I0017234 ! map3k3-ywhah physical interaction relationship: participates_in CCO:I0017356 ! map3k5-ywhah-1 physical interaction relationship: participates_in CCO:I0017393 ! grem1-14_3_3 eta-1 direct interaction relationship: participates_in CCO:I0017394 ! 14_3_3 eta-grem1 direct interaction relationship: participates_in CCO:I0018276 ! ywhah-prkci-1 physical interaction relationship: participates_in CCO:I0018278 ! prkci-par5-1 physical interaction relationship: participates_in CCO:I0018279 ! ywhah-mark4-1 physical interaction relationship: participates_in CCO:I0018289 ! mark4-ywhah-1 physical interaction relationship: participates_in CCO:I0018873 ! grem1-14_3_3 eta physical interaction relationship: participates_in CCO:I0019514 ! grem1-14_3_3 eta-2 physical interaction relationship: participates_in CCO:I0019515 ! 14_3_3 eta-grem1-1 physical interaction relationship: participates_in CCO:P0002128 ! glucocorticoid receptor signaling pathway relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002784 ! regulation of synaptic plasticity relationship: participates_in CCO:P0002952 ! negative regulation of dendrite morphogenesis relationship: transforms_into CCO:B0010368 ! 1433F_HUMAN-N-acetylglycine2 relationship: transforms_into CCO:B0031284 ! 1433F_HUMAN-Phosphotyrosine117 [Term] id: CCO:B0005491 name: RBX1_HUMAN def: "RING-box protein 1" [UniProtKB:P62877] synonym: "Protein ZYP" EXACT [UniProtKB:P62877] synonym: "Rbx1" EXACT [UniProtKB:P62877] synonym: "Regulator of cullins 1" EXACT [UniProtKB:P62877] synonym: "RING finger protein 75" EXACT [UniProtKB:P62877] xref: EMBL:AAD29715.1 xref: EMBL:AAD30146.1 xref: EMBL:AAH01466.1 xref: EMBL:AAH17370.2 xref: EMBL:AAM21718.1 xref: EMBL:CAB62925.1 xref: EMBL:CAG30446.1 xref: UniProtKB:P62877 xref: UniProtKB:Q8N6Z8 xref: UniProtKB:Q9D1S2 xref: UniProtKB:Q9WUK9 xref: UniProtKB:Q9Y254 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005453 ! RBX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006310 ! cul1-cand1-6 physical interaction relationship: participates_in CCO:I0006682 ! cul4b-tip120a-1 physical interaction relationship: participates_in CCO:I0006683 ! cul4a-tip120a-1 physical interaction relationship: participates_in CCO:I0006684 ! cul3-tip120a-2 physical interaction relationship: participates_in CCO:I0006685 ! cul1-tip120a-1 physical interaction relationship: participates_in CCO:I0006686 ! cul2-tip120a-2 physical interaction relationship: participates_in CCO:I0006687 ! cul4b-tip120a-2 physical interaction relationship: participates_in CCO:I0006693 ! cul1-tip120a-3 physical interaction relationship: participates_in CCO:I0006694 ! cul1-tip120a-4 physical interaction relationship: participates_in CCO:I0006796 ! cul1-rbx1-6 direct interaction relationship: participates_in CCO:I0006797 ! cul1-cul1-7 physical interaction relationship: participates_in CCO:I0006865 ! cand1-cul1-3 physical interaction relationship: participates_in CCO:I0006866 ! cul1-cand1-7 physical interaction relationship: participates_in CCO:I0006867 ! cul1-rbx1-5 physical interaction relationship: participates_in CCO:I0007108 ! cand1-cul1-1 physical interaction relationship: participates_in CCO:I0007109 ! cul1-cand1-2 physical interaction relationship: participates_in CCO:I0007113 ! cand1-cul1-4 physical interaction relationship: participates_in CCO:I0007114 ! cul1-cand1-8 physical interaction relationship: participates_in CCO:I0007504 ! cand1-cul1-5 physical interaction relationship: participates_in CCO:I0007733 ! skp2-cks1-4 physical interaction relationship: participates_in CCO:I0019485 ! tceb1-tceb2-4 physical interaction relationship: participates_in CCO:I0019486 ! tceb1-tceb2-5 physical interaction relationship: transforms_into CCO:B0041339 ! RBX1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005492 name: GPSM2_HUMAN def: "G-protein-signaling modulator 2" [UniProtKB:P81274] synonym: "Mosaic protein LGN" EXACT [UniProtKB:P81274] xref: EMBL:AAB40385.1 xref: EMBL:AAH27732.1 xref: EMBL:AAN01266.1 xref: UniProtKB:P81274 xref: UniProtKB:Q8N0Z5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004724 ! GPSM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006311 ! numa1-gpsm2-1 physical interaction relationship: participates_in CCO:I0006312 ! numa1-gnai1-1 physical interaction relationship: participates_in CCO:I0006967 ! gnai1-gpsm2-3 physical interaction relationship: participates_in CCO:I0006968 ! gpsm2-numa1-1 physical interaction relationship: participates_in CCO:I0007255 ! gpsm2-numa1-3 physical interaction relationship: participates_in CCO:I0007421 ! gpsm2-numa1-2 physical interaction relationship: participates_in CCO:I0007747 ! gnai1-gpsm2-2 physical interaction relationship: participates_in CCO:I0007750 ! gpsm2-numa1-4 physical interaction relationship: participates_in CCO:I0016279 ! gpsm2-gpsm2-4 physical interaction relationship: participates_in CCO:I0016280 ! gpsm2-gpsm2-5 physical interaction relationship: participates_in CCO:I0018061 ! gnai1-gpsm2-1 physical interaction relationship: participates_in CCO:I0018316 ! gpsm2-gpsm2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0011968 ! GPSM2_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0011969 ! GPSM2_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0011970 ! GPSM2_HUMAN-Phosphoserine401 relationship: transforms_into CCO:B0011971 ! GPSM2_HUMAN-Phosphoserine494 relationship: transforms_into CCO:B0011972 ! GPSM2_HUMAN-Phosphoserine600 relationship: transforms_into CCO:B0066555 ! GPSM2_HUMAN-Phosphoserine476 relationship: transforms_into CCO:B0066556 ! GPSM2_HUMAN-Phosphothreonine479 relationship: transforms_into CCO:B0066557 ! GPSM2_HUMAN-Phosphoserine534 [Term] id: CCO:B0005493 name: GNAI1_HUMAN def: "Guanine nucleotide-binding protein G(i), alpha-1 subunit" [UniProtKB:P63096] synonym: "Adenylate cyclase-inhibiting G alpha protein" EXACT [UniProtKB:P63096] xref: EMBL:AAA35893.1 xref: EMBL:AAA52581.1 xref: EMBL:AAC09361.1 xref: EMBL:AAH26326.1 xref: EMBL:AAM12619.1 xref: EMBL:AAV38580.1 xref: EMBL:CAB43212.2 xref: UniProtKB:P04898 xref: UniProtKB:P11015 xref: UniProtKB:P31871 xref: UniProtKB:P63096 xref: UniProtKB:Q5U074 xref: UniProtKB:Q8TAN5 xref: UniProtKB:Q9UGA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004709 ! GNAI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006312 ! numa1-gnai1-1 physical interaction relationship: participates_in CCO:I0006966 ! gnai1-numa1-1 physical interaction relationship: participates_in CCO:I0006967 ! gnai1-gpsm2-3 physical interaction relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0007747 ! gnai1-gpsm2-2 physical interaction relationship: participates_in CCO:I0018061 ! gnai1-gpsm2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0011949 ! GNAI1_HUMAN-ADP-ribosylarginine178 relationship: transforms_into CCO:B0011950 ! GNAI1_HUMAN-ADP-ribosylcysteine351 [Term] id: CCO:B0005494 name: LSM7_HUMAN def: "U6 snRNA-associated Sm-like protein LSm7" [UniProtKB:Q9UK45] xref: EMBL:AAD56231.1 xref: EMBL:AAG45442.1 xref: EMBL:AAH18621.1 xref: UniProtKB:Q9UK45 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004994 ! LSM7_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003545 ! U6 snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0006314 ! tacc1-lsm7-2 physical interaction relationship: participates_in CCO:I0017324 ! lsm7-rab7l1 physical interaction relationship: participates_in CCO:I0017325 ! lsm7-npy1r physical interaction [Term] id: CCO:B0005495 name: RUXG_HUMAN def: "Small nuclear ribonucleoprotein G" [UniProtKB:P62308] synonym: "Sm protein G" EXACT [UniProtKB:P62308] synonym: "Sm-G" EXACT [UniProtKB:P62308] synonym: "SmG" EXACT [UniProtKB:P62308] synonym: "snRNP-G" EXACT [UniProtKB:P62308] xref: EMBL:AAH00070.1 xref: EMBL:AAH22432.1 xref: EMBL:AAH66302.1 xref: EMBL:AAH70166.1 xref: EMBL:AAH71880.1 xref: EMBL:AAI06056.1 xref: EMBL:AAX81996.1 xref: EMBL:CAA59689.1 xref: EMBL:CAG33199.1 xref: EMBL:EAW99817.1 xref: UniProtKB:P62308 xref: UniProtKB:Q15357 xref: UniProtKB:Q6IB86 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005550 ! SNRPG_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: participates_in CCO:I0006315 ! tacc1-snrpg-2 physical interaction relationship: participates_in CCO:I0015030 ! ddit4l-snrpg physical interaction relationship: participates_in CCO:I0019840 ! snrpg-tle1 physical interaction relationship: participates_in CCO:I0020172 ! snrpg-gdf9 physical interaction [Term] id: CCO:B0005496 name: TDRD7_HUMAN def: "Tudor domain-containing protein 7" [UniProtKB:Q8NHU6] synonym: "PCTAIRE2-binding protein" EXACT [UniProtKB:Q8NHU6] synonym: "Trap" EXACT [UniProtKB:Q8NHU6] synonym: "Tudor repeat associator with PCTAIRE 2" EXACT [UniProtKB:Q8NHU6] xref: EMBL:AAH28694.1 xref: EMBL:BAA76379.1 xref: EMBL:CAB59271.1 xref: EMBL:CAH71605.1 xref: EMBL:CAI14933.1 xref: UniProtKB:A6NCI6 xref: UniProtKB:Q5VV27 xref: UniProtKB:Q8NHU6 xref: UniProtKB:Q96JT1 xref: UniProtKB:Q9UFF0 xref: UniProtKB:Q9Y2M3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005757 ! TDRD7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0006316 ! tacc1-tdrd7-6 physical interaction relationship: participates_in CCO:I0006969 ! tacc1-tdrd7-8 physical interaction relationship: participates_in CCO:I0007354 ! tacc1-tdrd7-1 physical interaction relationship: participates_in CCO:I0007567 ! tacc1-tdrd7-7 physical interaction relationship: participates_in CCO:I0015685 ! gabpb2-tdrd7 physical interaction relationship: participates_in CCO:I0019116 ! atxn2-tdrd7 physical interaction [Term] id: CCO:B0005497 name: ARID2_HUMAN def: "AT-rich interactive domain-containing protein 2" [UniProtKB:Q68CP9] synonym: "ARID domain-containing protein 2" EXACT [UniProtKB:Q68CP9] synonym: "BAF200" EXACT [UniProtKB:Q68CP9] synonym: "BRG1-associated factor 200" EXACT [UniProtKB:Q68CP9] synonym: "Zinc finger protein with activation potential" EXACT [UniProtKB:Q68CP9] synonym: "Zipzap/p200" EXACT [UniProtKB:Q68CP9] xref: EMBL:AAH90062.1 xref: EMBL:AAU20329.2 xref: EMBL:AAZ74794.1 xref: EMBL:BAB13383.1 xref: EMBL:BAB55320.1 xref: EMBL:BAC87171.1 xref: EMBL:CAD91164.1 xref: EMBL:CAD97878.1 xref: EMBL:CAH18689.1 xref: UniProtKB:Q15KG9 xref: UniProtKB:Q5EB51 xref: UniProtKB:Q645I3 xref: UniProtKB:Q68CP9 xref: UniProtKB:Q6ZRY5 xref: UniProtKB:Q7Z3I5 xref: UniProtKB:Q86T28 xref: UniProtKB:Q96SJ6 xref: UniProtKB:Q9HCL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004094 ! ARID2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006322 ! pb1-arid2-4 physical interaction relationship: participates_in CCO:I0006729 ! pb1-arid2-2 physical interaction relationship: participates_in CCO:I0007258 ! smarcb1-arid2-1 physical interaction relationship: participates_in CCO:I0007259 ! arid2-pb1-1 physical interaction relationship: participates_in CCO:I0007356 ! pb1-arid2-3 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0007961 ! pb1-arid2-1 physical interaction relationship: participates_in CCO:I0017376 ! pb1-arid2-5 physical interaction relationship: participates_in CCO:I0019259 ! smarca4-arid2-1 physical interaction relationship: participates_in CCO:I0019260 ! smarce1-arid2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063589 ! ARID2_HUMAN-Phosphoserine631 relationship: transforms_into CCO:B0063590 ! ARID2_HUMAN-Phosphoserine635 relationship: transforms_into CCO:B0063591 ! ARID2_HUMAN-Phosphothreonine653 relationship: transforms_into CCO:B0063592 ! ARID2_HUMAN-Phosphoserine689 relationship: transforms_into CCO:B0063593 ! ARID2_HUMAN-Phosphothreonine692 relationship: transforms_into CCO:B0063594 ! ARID2_HUMAN-Phosphoserine1496 [Term] id: CCO:B0005498 name: CREB3_HUMAN def: "Cyclic AMP-responsive element-binding protein 3" [UniProtKB:O43889] synonym: "Luman protein" EXACT [UniProtKB:O43889] synonym: "Transcription factor LZIP-alpha" EXACT [UniProtKB:O43889] xref: EMBL:AAB69652.1 xref: EMBL:AAB84166.1 xref: EMBL:AAC04325.1 xref: EMBL:AAD09210.1 xref: EMBL:AAG43527.1 xref: EMBL:AAG43528.1 xref: EMBL:AAH09402.1 xref: EMBL:AAH10158.1 xref: UniProtKB:O14671 xref: UniProtKB:O14919 xref: UniProtKB:O43889 xref: UniProtKB:Q96GK8 xref: UniProtKB:Q9H2W3 xref: UniProtKB:Q9UE77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004396 ! CREB3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006323 ! hcfc1-creb3-2 physical interaction relationship: participates_in CCO:I0007264 ! hcfc1-creb3-3 direct interaction relationship: participates_in CCO:I0007265 ! hcfc1-zf-6 direct interaction relationship: participates_in CCO:I0007266 ! hcfc1-creb3-4 direct interaction relationship: participates_in CCO:I0007752 ! hcfc1-creb3-1 physical interaction relationship: participates_in CCO:I0007755 ! hcfc1-zf-5 physical interaction relationship: participates_in CCO:I0015032 ! creb3-stx8 physical interaction relationship: participates_in CCO:I0015232 ! appbp2-creb3 physical interaction relationship: participates_in CCO:I0015323 ! creb3-emd physical interaction relationship: participates_in CCO:I0015556 ! bene-creb3 physical interaction relationship: participates_in CCO:I0015815 ! bnip2-creb3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005499 name: MAST3_HUMAN def: "Microtubule-associated serine/threonine-protein kinase 3" [UniProtKB:O60307] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O60307] xref: EMBL:AAC62830.1 xref: EMBL:AAD22670.1 xref: EMBL:BAA25487.1 xref: UniProtKB:O60307 xref: UniProtKB:Q7LDZ8 xref: UniProtKB:Q9UPI0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005029 ! MAST3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006324 ! pten-mast3-3 phosphorylation relationship: participates_in CCO:I0007572 ! pten-mast3-2 physical interaction relationship: participates_in CCO:I0007757 ! pten-mast3-1 physical interaction relationship: transforms_into CCO:B0012778 ! MAST3_HUMAN-Phosphoserine1223 relationship: transforms_into CCO:B0012779 ! MAST3_HUMAN-Phosphoserine1273 [Term] id: CCO:B0005500 name: RFA2_HUMAN def: "Replication protein A 32 kDa subunit" [UniProtKB:P15927] synonym: "Replication factor A protein 2" EXACT [UniProtKB:P15927] synonym: "RF-A protein 2" EXACT [UniProtKB:P15927] synonym: "RP-A p32" EXACT [UniProtKB:P15927] synonym: "RP-A p34" EXACT [UniProtKB:P15927] xref: EMBL:AAA36560.1 xref: EMBL:AAH01630.1 xref: EMBL:AAH12157.1 xref: EMBL:AAH21257.1 xref: EMBL:AAX84514.1 xref: EMBL:CAG29344.1 xref: EMBL:CAI21775.1 xref: EMBL:CAI21777.1 xref: EMBL:CAI21778.1 xref: UniProtKB:P15927 xref: UniProtKB:Q52II0 xref: UniProtKB:Q5TEI9 xref: UniProtKB:Q5TEJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005470 ! RPA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006325 ! rpa1-rpa2-1 direct interaction relationship: participates_in CCO:I0007282 ! rpa1-rpa2-2 physical interaction relationship: participates_in CCO:I0007422 ! blm-c9orf76-2 physical interaction relationship: participates_in CCO:I0007427 ! c9orf76-blm-2 physical interaction relationship: participates_in CCO:I0007498 ! rpa1-rpa2-3 physical interaction relationship: participates_in CCO:I0007748 ! c9orf76-blm-1 physical interaction relationship: participates_in CCO:I0007749 ! blm-c9orf76-1 physical interaction relationship: participates_in CCO:I0007990 ! rpa2-rif1 physical interaction relationship: participates_in CCO:I0018334 ! rpa2-rpa3-1 physical interaction relationship: participates_in CCO:I0019322 ! rpa2-rpa3-2 direct interaction relationship: participates_in CCO:I0019541 ! rpa2-med31 physical interaction relationship: participates_in CCO:I0019542 ! rpa2-crmp1 physical interaction relationship: participates_in CCO:I0019543 ! rpa2-eef1a1 physical interaction relationship: participates_in CCO:I0019544 ! rpa2-kiaa1377 physical interaction relationship: participates_in CCO:I0019545 ! rpa2-utp14a physical interaction relationship: participates_in CCO:I0019546 ! rpa2-tle1 physical interaction relationship: participates_in CCO:I0019612 ! rpa2-rplp1 physical interaction relationship: participates_in CCO:I0019613 ! rpa2-unc119 physical interaction relationship: participates_in CCO:I0019814 ! rpa2-cops6 physical interaction relationship: participates_in CCO:I0019815 ! rpa2-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020013 ! golph2-rpa2 physical interaction relationship: participates_in CCO:I0020331 ! herpud1-rpa2 physical interaction relationship: participates_in CCO:I0020440 ! rpa2-acp5 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: transforms_into CCO:B0013823 ! RFA2_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0013824 ! RFA2_HUMAN-Phosphothreonine21 relationship: transforms_into CCO:B0013825 ! RFA2_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0013826 ! RFA2_HUMAN-Phosphoserine33 [Term] id: CCO:B0005501 name: RFA3_HUMAN def: "Replication protein A 14 kDa subunit" [UniProtKB:P35244] synonym: "Replication factor A protein 3" EXACT [UniProtKB:P35244] synonym: "RF-A protein 3" EXACT [UniProtKB:P35244] synonym: "RP-A p14" EXACT [UniProtKB:P35244] xref: EMBL:AAA58350.1 xref: EMBL:AAH05264.1 xref: EMBL:AAH09868.1 xref: EMBL:AAP35984.1 xref: EMBL:AAQ96878.1 xref: EMBL:AAX84517.1 xref: UniProtKB:P35244 xref: UniProtKB:Q549U6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005471 ! RPA3_human relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000267 ! DNA replication factor A complex relationship: participates_in CCO:I0006325 ! rpa1-rpa2-1 direct interaction relationship: participates_in CCO:I0007498 ! rpa1-rpa2-3 physical interaction relationship: participates_in CCO:I0007749 ! blm-c9orf76-1 physical interaction relationship: participates_in CCO:I0018334 ! rpa2-rpa3-1 physical interaction relationship: participates_in CCO:I0019322 ! rpa2-rpa3-2 direct interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0005502 name: BLM_HUMAN def: "Bloom syndrome protein" [UniProtKB:P54132] synonym: "DNA helicase, RecQ-like type 2" EXACT [UniProtKB:P54132] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P54132] synonym: "RecQ protein-like 3" EXACT [UniProtKB:P54132] xref: EMBL:AAA87850.1 xref: EMBL:AAH93622.1 xref: EMBL:AAI01568.1 xref: EMBL:AAI15031.1 xref: EMBL:AAI15033.1 xref: EMBL:AAW62255.1 xref: UniProtKB:P54132 xref: UniProtKB:Q52M96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004168 ! BLM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006326 ! blm-terf1-6 direct interaction relationship: participates_in CCO:I0006538 ! blm-terf2-4 colocalization relationship: participates_in CCO:I0006879 ! blm-terf1-7 direct interaction relationship: participates_in CCO:I0006880 ! blm-terf1-8 direct interaction relationship: participates_in CCO:I0006881 ! blm-terf2-9 direct interaction relationship: participates_in CCO:I0006882 ! blm-terf2-10 direct interaction relationship: participates_in CCO:I0007283 ! blm-terf2-1 physical interaction relationship: participates_in CCO:I0007358 ! blm-terf2-2 physical interaction relationship: participates_in CCO:I0007359 ! blm-terf2-5 colocalization relationship: participates_in CCO:I0007422 ! blm-c9orf76-2 physical interaction relationship: participates_in CCO:I0007427 ! c9orf76-blm-2 physical interaction relationship: participates_in CCO:I0007574 ! blm-terf2-3 direct interaction relationship: participates_in CCO:I0007748 ! c9orf76-blm-1 physical interaction relationship: participates_in CCO:I0007749 ! blm-c9orf76-1 physical interaction relationship: participates_in CCO:I0007762 ! blm-rpa1-1 physical interaction relationship: participates_in CCO:I0007763 ! blm-rpa1-2 physical interaction relationship: participates_in CCO:I0007768 ! blm-terf2-6 direct interaction relationship: participates_in CCO:I0008561 ! c9orf76-blm-4 colocalization relationship: participates_in CCO:I0008562 ! blm-fen1-2 physical interaction relationship: participates_in CCO:I0008563 ! blm-fen1-4 physical interaction relationship: participates_in CCO:I0008565 ! c9orf76-blm-3 physical interaction relationship: participates_in CCO:I0008566 ! wrn-blm-11 physical interaction relationship: participates_in CCO:I0008570 ! wrn-blm-4 colocalization relationship: participates_in CCO:I0008571 ! wrn-blm-6 direct interaction relationship: participates_in CCO:I0008572 ! wrn-blm-7 direct interaction relationship: participates_in CCO:I0008573 ! wrn-blm-9 direct interaction relationship: participates_in CCO:I0008574 ! wrn-blm-2 colocalization relationship: participates_in CCO:I0008575 ! wrn-blm-5 physical interaction relationship: participates_in CCO:I0008578 ! wrn-blm-3 colocalization relationship: participates_in CCO:I0008580 ! blm-fen1-1 direct interaction relationship: participates_in CCO:I0008583 ! blm-fen1-3 direct interaction relationship: participates_in CCO:I0008584 ! wrn-blm-1 direct interaction relationship: participates_in CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000015 ! G2 phase of mitotic cell cycle relationship: participates_in CCO:P0000185 ! G2/M transition DNA damage checkpoint relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0002607 ! negative regulation of DNA recombination relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002633 ! negative regulation of mitotic recombination relationship: participates_in CCO:P0002716 ! positive regulation of alpha-beta T cell proliferation relationship: participates_in CCO:P0002848 ! replication fork protection relationship: participates_in CCO:P0003144 ! negative regulation of cell division relationship: transforms_into CCO:B0010800 ! BLM_HUMAN-Phosphoserine419 relationship: transforms_into CCO:B0010801 ! BLM_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0010802 ! BLM_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: transforms_into CCO:B0010804 ! BLM_HUMAN-Phosphothreonine508 relationship: transforms_into CCO:B0010805 ! BLM_HUMAN-Phosphoserine1296 relationship: transforms_into CCO:B0063928 ! BLM_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0063929 ! BLM_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0063930 ! BLM_HUMAN-Phosphothreonine57 relationship: transforms_into CCO:B0063931 ! BLM_HUMAN-Phosphothreonine114 relationship: transforms_into CCO:B0063932 ! BLM_HUMAN-Phosphoserine358 relationship: transforms_into CCO:B0063933 ! BLM_HUMAN-Phosphoserine1295 relationship: transforms_into CCO:B0063934 ! BLM_HUMAN-Phosphoserine1303 relationship: transforms_into CCO:B0063935 ! BLM_HUMAN-Phosphoserine1310 [Term] id: CCO:B0005503 name: POTE1_HUMAN def: "Protection of telomeres protein 1" [UniProtKB:Q9NUX5] synonym: "hPot1" EXACT [UniProtKB:Q9NUX5] synonym: "POT1-like telomere end-binding protein" EXACT [UniProtKB:Q9NUX5] xref: EMBL:AAD08852.1 xref: EMBL:AAH02923.1 xref: EMBL:BAA91568.1 xref: EMBL:BAA91988.1 xref: EMBL:BAB14110.1 xref: EMBL:BAB15404.1 xref: EMBL:CAB43281.1 xref: UniProtKB:O95018 xref: UniProtKB:Q9H662 xref: UniProtKB:Q9NUX5 xref: UniProtKB:Q9NW19 xref: UniProtKB:Q9UG95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005355 ! POT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005790 ! single-stranded telomeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000111 ! nuclear chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0006327 ! pot1-terf2 physical interaction relationship: participates_in CCO:I0006328 ! acd-terf2 physical interaction relationship: participates_in CCO:I0006329 ! rap1-terf2-2 physical interaction relationship: participates_in CCO:I0006330 ! terf2-tinf2 physical interaction relationship: participates_in CCO:I0007893 ! pot1-terf2-1 physical interaction relationship: participates_in CCO:I0015851 ! acd-pot1 physical interaction relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase [Term] id: CCO:B0005504 name: ACD_HUMAN def: "Adrenocortical dysplasia protein homolog" [UniProtKB:Q96AP0] synonym: "POT1 and TIN2-interacting protein" EXACT [UniProtKB:Q96AP0] xref: EMBL:AAH16904.1 xref: EMBL:AAS80318.1 xref: EMBL:AAX82621.1 xref: EMBL:BAB14658.1 xref: UniProtKB:Q562H5 xref: UniProtKB:Q96AP0 xref: UniProtKB:Q9H8F9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004015 ! ACD_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000110 ! nuclear telomere cap complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0006328 ! acd-terf2 physical interaction relationship: participates_in CCO:I0007893 ! pot1-terf2-1 physical interaction relationship: participates_in CCO:I0015851 ! acd-pot1 physical interaction relationship: participates_in CCO:I0020219 ! acd-g22p1 physical interaction relationship: transforms_into CCO:B0048155 ! ACD_HUMAN-Phosphothreonine422 relationship: transforms_into CCO:B0048156 ! ACD_HUMAN-Phosphoserine425 [Term] id: CCO:B0005505 name: TE2IP_HUMAN def: "Telomeric repeat-binding factor 2-interacting protein 1" [UniProtKB:Q9NYB0] synonym: "hRap1" EXACT [UniProtKB:Q9NYB0] synonym: "TRF2-interacting telomeric protein Rap1" EXACT [UniProtKB:Q9NYB0] xref: EMBL:AAF72711.1 xref: EMBL:AAH04465.1 xref: EMBL:AAH05841.1 xref: EMBL:AAH22428.1 xref: EMBL:AAH78171.1 xref: EMBL:AAL55783.1 xref: EMBL:BAA91317.1 xref: UniProtKB:Q8WYZ3 xref: UniProtKB:Q9NWR2 xref: UniProtKB:Q9NYB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005758 ! TERF2IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006329 ! rap1-terf2-2 physical interaction relationship: participates_in CCO:I0006331 ! rap1-terf2-3 physical interaction relationship: participates_in CCO:I0007131 ! terf2ip-rad50 physical interaction relationship: participates_in CCO:I0007893 ! pot1-terf2-1 physical interaction relationship: participates_in CCO:I0015562 ! ap2b1-terf2ip physical interaction relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: participates_in CCO:P0001547 ! negative regulation of telomere maintenance relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014328 ! TE2IP_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0014329 ! TE2IP_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0014330 ! TE2IP_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0014331 ! TE2IP_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0071313 ! TE2IP_HUMAN-Phosphoserine36 [Term] id: CCO:B0005506 name: FSHR_HUMAN def: "Follicle-stimulating hormone receptor precursor" [UniProtKB:P23945] synonym: "Follitropin receptor" EXACT [UniProtKB:P23945] synonym: "FSH-R" EXACT [UniProtKB:P23945] xref: EMBL:AAA52477.1 xref: EMBL:AAA52478.1 xref: EMBL:AAB26480.1 xref: EMBL:AAB32071.1 xref: EMBL:AAB32225.1 xref: EMBL:AAH96831.1 xref: EMBL:AAI18549.1 xref: EMBL:AAR07899.1 xref: EMBL:CAA48179.1 xref: UniProtKB:P23945 xref: UniProtKB:Q16225 xref: UniProtKB:Q4QRJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004661 ! FSHR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001304 ! follicle-stimulating hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006336 ! fshr-ywhaq-3 physical interaction relationship: participates_in CCO:I0006884 ! fshr-ywhaq-1 physical interaction relationship: participates_in CCO:I0007288 ! fshr-ywhaq-2 physical interaction relationship: participates_in CCO:I0018403 ! cga-fshb-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0005507 name: PRI1_HUMAN def: "DNA primase small subunit" [UniProtKB:P49642] synonym: "DNA primase 49 kDa subunit" EXACT [UniProtKB:P49642] synonym: "EC 2.7.7.-" EXACT [UniProtKB:P49642] synonym: "p49" EXACT [UniProtKB:P49642] xref: EMBL:AAC51726.1 xref: EMBL:AAH05266.1 xref: EMBL:CAA52377.1 xref: UniProtKB:P49642 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005375 ! PRIM1_human relationship: has_function CCO:F0000407 ! DNA primase activity relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000266 ! alpha DNA polymerase:primase complex relationship: participates_in CCO:I0006337 ! pola-pola2-6 physical interaction relationship: participates_in CCO:I0006338 ! pola-pri1-1 physical interaction relationship: participates_in CCO:I0007909 ! pol-prim_human physical interaction relationship: participates_in CCO:I0020604 ! mrpl38-prim1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000633 ! DNA replication, synthesis of RNA primer [Term] id: CCO:B0005508 name: PRI2_HUMAN def: "DNA primase large subunit" [UniProtKB:P49643] synonym: "DNA primase 58 kDa subunit" EXACT [UniProtKB:P49643] synonym: "EC 2.7.7.-" EXACT [UniProtKB:P49643] synonym: "p58" EXACT [UniProtKB:P49643] xref: EMBL:AAH17833.1 xref: EMBL:AAH64931.1 xref: EMBL:CAA52378.1 xref: EMBL:CAH73686.1 xref: EMBL:CAI20534.1 xref: UniProtKB:P49643 xref: UniProtKB:Q53FJ8 xref: UniProtKB:Q6P1Q7 xref: UniProtKB:Q8WVL2 xref: UniProtKB:Q9H413 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006367 ! PRIM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006337 ! pola-pola2-6 physical interaction relationship: participates_in CCO:I0006338 ! pola-pri1-1 physical interaction relationship: participates_in CCO:I0007909 ! pol-prim_human physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000633 ! DNA replication, synthesis of RNA primer relationship: transforms_into CCO:B0013612 ! PRI2_HUMAN-Phosphotyrosine381 [Term] id: CCO:B0005509 name: DPOA2_HUMAN def: "DNA polymerase subunit alpha B" [UniProtKB:Q14181] synonym: "DNA polymerase alpha 70 kDa subunit" EXACT [UniProtKB:Q14181] xref: EMBL:AAA16459.1 xref: EMBL:AAH01347.1 xref: EMBL:AAH02990.1 xref: EMBL:CAG33018.1 xref: UniProtKB:Q14181 xref: UniProtKB:Q9BPV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004500 ! POLA2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000266 ! alpha DNA polymerase:primase complex relationship: participates_in CCO:I0006337 ! pola-pola2-6 physical interaction relationship: participates_in CCO:I0007909 ! pol-prim_human physical interaction relationship: participates_in CCO:I0008282 ! nhp2l1-pola2 physical interaction relationship: participates_in CCO:I0019662 ! ascc2-pola2 physical interaction relationship: participates_in CCO:I0019664 ! atp5c1-pola2 physical interaction relationship: participates_in CCO:I0019705 ! ddx24-pola2 physical interaction relationship: participates_in CCO:I0019714 ! ezh2-pola2 physical interaction relationship: participates_in CCO:I0019722 ! fts-pola2 physical interaction relationship: participates_in CCO:I0019750 ! itgb3bp-pola2 physical interaction relationship: participates_in CCO:I0019953 ! klf6-pola2 physical interaction relationship: participates_in CCO:I0019956 ! cpe-pola2 physical interaction relationship: participates_in CCO:I0019961 ! creld1-pola2 physical interaction relationship: participates_in CCO:I0020000 ! fgfr3-pola2 physical interaction relationship: participates_in CCO:I0020003 ! rp5_965l7_1-pola2 physical interaction relationship: participates_in CCO:I0020053 ! loc51236-pola2 physical interaction relationship: participates_in CCO:I0020054 ! lrpap1-pola2 physical interaction relationship: participates_in CCO:I0020116 ! pola2-setdb1 physical interaction relationship: participates_in CCO:I0020150 ! rnpc4-pola2 physical interaction relationship: participates_in CCO:I0020263 ! c9orf25-pola2 physical interaction relationship: participates_in CCO:I0020291 ! dhx34-pola2 physical interaction relationship: participates_in CCO:I0020339 ! igfbp3-pola2 physical interaction relationship: participates_in CCO:I0020492 ! ulk2-pola2 physical interaction relationship: participates_in CCO:I0020496 ! xpnpep1-pola2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0011568 ! DPOA2_HUMAN-Phosphothreonine127 relationship: transforms_into CCO:B0011569 ! DPOA2_HUMAN-Phosphothreonine130 relationship: transforms_into CCO:B0011570 ! DPOA2_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0011571 ! DPOA2_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0064851 ! DPOA2_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0064852 ! DPOA2_HUMAN-Phosphoserine147 relationship: transforms_into CCO:B0064853 ! DPOA2_HUMAN-Phosphoserine149 [Term] id: CCO:B0005510 name: MBD1_HUMAN def: "Methyl-CpG-binding domain protein 1" [UniProtKB:Q9UIS9] synonym: "CXXC-type zinc finger protein 3" EXACT [UniProtKB:Q9UIS9] synonym: "Methyl-CpG-binding protein MBD1" EXACT [UniProtKB:Q9UIS9] synonym: "Protein containing methyl-CpG-binding domain 1" EXACT [UniProtKB:Q9UIS9] xref: EMBL:AAC68870.1 xref: EMBL:AAD50371.1 xref: EMBL:AAD51442.1 xref: EMBL:AAD51443.1 xref: EMBL:AAD51444.1 xref: EMBL:AAD51445.1 xref: EMBL:AAH33242.1 xref: EMBL:ABP02056.1 xref: EMBL:CAA71735.1 xref: EMBL:CAD92308.1 xref: UniProtKB:A4UTZ0 xref: UniProtKB:O15248 xref: UniProtKB:O95241 xref: UniProtKB:Q7Z7B5 xref: UniProtKB:Q8N4W4 xref: UniProtKB:Q9UIS9 xref: UniProtKB:Q9UNZ6 xref: UniProtKB:Q9UNZ7 xref: UniProtKB:Q9UNZ8 xref: UniProtKB:Q9UNZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005034 ! MBD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006339 ! rar-mbd1 physical interaction relationship: participates_in CCO:I0006904 ! mbde-suv93h1-1 physical interaction relationship: participates_in CCO:I0006905 ! suv93h1-mbde-1 physical interaction relationship: participates_in CCO:I0006906 ! suv93h1-mbd1-4 colocalization relationship: participates_in CCO:I0007134 ! hdac3-mbd1-1 physical interaction relationship: participates_in CCO:I0007450 ! hdac3-mbd1 physical interaction relationship: participates_in CCO:I0007972 ! mbde-suv93h1-2 physical interaction relationship: participates_in CCO:I0007973 ! suv93h1-mbde-2 physical interaction relationship: participates_in CCO:I0016314 ! rar-mbd1-1 physical interaction relationship: participates_in CCO:I0017943 ! suv93h1-cbx5-3 colocalization relationship: participates_in CCO:I0018243 ! cbx5-mbd1-1 physical interaction relationship: participates_in CCO:I0018390 ! mbd1-cbx5-2 physical interaction relationship: participates_in CCO:I0018698 ! mbd1-cbx5-1 physical interaction relationship: participates_in CCO:I0018699 ! mbd1-hdac1-3 physical interaction relationship: participates_in CCO:I0018700 ! mbd1-hdac2-3 physical interaction relationship: participates_in CCO:I0019521 ! mbde-cbx5-1 physical interaction relationship: participates_in CCO:I0019522 ! mbde-hdac1-1 physical interaction relationship: participates_in CCO:I0019523 ! mbde-hdac2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0012800 ! MBD1_HUMAN-Phosphotyrosine52 relationship: transforms_into CCO:B0012801 ! MBD1_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0012802 ! MBD1_HUMAN-Phosphothreonine301 relationship: transforms_into CCO:B0068039 ! MBD1_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0068040 ! MBD1_HUMAN-Phosphoserine399 [Term] id: CCO:B0005511 name: TLE1_HUMAN def: "Transducin-like enhancer protein 1" [UniProtKB:Q04724] synonym: "E(Sp1) homolog" EXACT [UniProtKB:Q04724] synonym: "ESG1" EXACT [UniProtKB:Q04724] xref: EMBL:AAA61192.1 xref: EMBL:AAH10100.1 xref: EMBL:AAH15747.1 xref: EMBL:CAI12595.1 xref: EMBL:CAI14977.1 xref: UniProtKB:Q04724 xref: UniProtKB:Q5T3G4 xref: UniProtKB:Q969V9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005788 ! TLE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006341 ! aml2-tle1-1 direct interaction relationship: participates_in CCO:I0006551 ! aml2-tle1-2 physical interaction relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0007292 ! tle1-aml2-1 physical interaction relationship: participates_in CCO:I0008011 ! erh-tle1 physical interaction relationship: participates_in CCO:I0008022 ! mphosph6-tle1 physical interaction relationship: participates_in CCO:I0008084 ! cdkn2c-tle1 physical interaction relationship: participates_in CCO:I0008222 ! dleu1-tle1 physical interaction relationship: participates_in CCO:I0016320 ! lef1-tle1-1 direct interaction relationship: participates_in CCO:I0019536 ! fubp1-tle1 physical interaction relationship: participates_in CCO:I0019546 ! rpa2-tle1 physical interaction relationship: participates_in CCO:I0019548 ! sat-tle1 physical interaction relationship: participates_in CCO:I0019554 ! zfp64-tle1 physical interaction relationship: participates_in CCO:I0019560 ! arf4l-tle1 physical interaction relationship: participates_in CCO:I0019570 ! btbd2-tle1 physical interaction relationship: participates_in CCO:I0019588 ! eif2s2-tle1 physical interaction relationship: participates_in CCO:I0019594 ! hspe1-tle1 physical interaction relationship: participates_in CCO:I0019605 ! pafah1b3-tle1 physical interaction relationship: participates_in CCO:I0019606 ! pcdha4-tle1 physical interaction relationship: participates_in CCO:I0019610 ! psmd11-tle1 physical interaction relationship: participates_in CCO:I0019619 ! serpinb9-tle1 physical interaction relationship: participates_in CCO:I0019633 ! tk1-tle1 physical interaction relationship: participates_in CCO:I0019654 ! arl3-tle1 physical interaction relationship: participates_in CCO:I0019686 ! ccl18-tle1 physical interaction relationship: participates_in CCO:I0019724 ! fxyd6-tle1 physical interaction relationship: participates_in CCO:I0019726 ! gstm4-tle1 physical interaction relationship: participates_in CCO:I0019732 ! hla_dqa1-tle1 physical interaction relationship: participates_in CCO:I0019791 ! pole2-tle1 physical interaction relationship: participates_in CCO:I0019807 ! pxmp3-tle1 physical interaction relationship: participates_in CCO:I0019813 ! rnf10-tle1 physical interaction relationship: participates_in CCO:I0019840 ! snrpg-tle1 physical interaction relationship: participates_in CCO:I0019864 ! tmsb4x-tle1 physical interaction relationship: participates_in CCO:I0020106 ! pfn1-tle1 physical interaction relationship: participates_in CCO:I0020117 ! polb-tle1 physical interaction relationship: participates_in CCO:I0020535 ! dazap2-tle1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014389 ! TLE1_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0014390 ! TLE1_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0014391 ! TLE1_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0014392 ! TLE1_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0014393 ! TLE1_HUMAN-Phosphoserine284 [Term] id: CCO:B0005512 name: AKT1_HUMAN def: "RAC-alpha serine/threonine-protein kinase" [UniProtKB:P31749] synonym: "C-AKT" EXACT [UniProtKB:P31749] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P31749] synonym: "PKB" EXACT [UniProtKB:P31749] synonym: "Protein kinase B" EXACT [UniProtKB:P31749] synonym: "RAC-PK-alpha" EXACT [UniProtKB:P31749] xref: EMBL:AAA36539.1 xref: EMBL:AAH00479.1 xref: EMBL:AAH84538.1 xref: EMBL:AAL55732.1 xref: EMBL:CAA43372.1 xref: UniProtKB:P31749 xref: UniProtKB:Q9BWB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004045 ! AKT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001577 ! sugar:hydrogen symporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:I0006342 ! bcl10-akt1-3 physical interaction relationship: participates_in CCO:I0007374 ! bcl10-akt1-4 physical interaction relationship: participates_in CCO:I0007396 ! cdc37-hsp90 physical interaction relationship: participates_in CCO:I0007397 ! cdc37-akt1 physical interaction relationship: participates_in CCO:I0007795 ! bcl10-akt1-1 physical interaction relationship: participates_in CCO:I0007796 ! bcl10-akt1-2 physical interaction relationship: participates_in CCO:I0018690 ! gsk3b-akt1-1 phosphorylation relationship: participates_in CCO:I0018766 ! akt1-akt1-1 physical interaction relationship: participates_in CCO:I0018768 ! ppl-akt1-2 physical interaction relationship: participates_in CCO:I0018782 ! akt1-akt1-2 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0000844 ! apoptotic mitochondrial changes relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002225 ! protein kinase B signaling cascade relationship: participates_in CCO:P0002591 ! regulation of survival gene product expression relationship: participates_in CCO:P0002755 ! insulin-like growth factor receptor signaling pathway relationship: transforms_into CCO:B0010487 ! AKT1_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0010488 ! AKT1_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0010489 ! AKT1_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0010490 ! AKT1_HUMAN-Phosphothreonine308 relationship: transforms_into CCO:B0010491 ! AKT1_HUMAN-Phosphoserine473 relationship: transforms_into CCO:B0010492 ! AKT1_HUMAN-Phosphotyrosine474 [Term] id: CCO:B0005513 name: BCL3_HUMAN def: "B-cell lymphoma 3-encoded protein" [UniProtKB:P20749] synonym: "Protein Bcl-3" EXACT [UniProtKB:P20749] xref: EMBL:AAA51815.1 xref: EMBL:AAA51816.1 xref: EMBL:AAC51348.1 xref: EMBL:AAH64993.1 xref: UniProtKB:P20749 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004152 ! BCL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006343 ! bcl10-bcl3-3 physical interaction relationship: participates_in CCO:I0007797 ! bcl10-bcl3-1 physical interaction relationship: participates_in CCO:I0007798 ! bcl10-bcl3-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator relationship: participates_in CCO:P0002100 ! negative regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002274 ! positive regulation of interleukin-10 biosynthetic process relationship: participates_in CCO:P0002356 ! negative regulation of interleukin-8 biosynthetic process relationship: participates_in CCO:P0002524 ! positive regulation of translation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0041126 ! BCL3_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0041127 ! BCL3_HUMAN-Phosphoserine398 [Term] id: CCO:B0005514 name: CEBPB_HUMAN def: "CCAAT/enhancer-binding protein beta" [UniProtKB:P17676] synonym: "C/EBP beta" EXACT [UniProtKB:P17676] synonym: "Nuclear factor NF-IL6" EXACT [UniProtKB:P17676] synonym: "Transcription factor 5" EXACT [UniProtKB:P17676] xref: EMBL:AAH07538.1 xref: EMBL:AAH21931.1 xref: EMBL:AAL55792.1 xref: EMBL:AAN86350.1 xref: EMBL:CAA36794.1 xref: EMBL:CAC14276.1 xref: UniProtKB:P17676 xref: UniProtKB:Q96IH2 xref: UniProtKB:Q9H4Z5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004317 ! CEBPB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006344 ! tp53-lap-2 colocalization relationship: participates_in CCO:I0006554 ! tp53-lip physical interaction relationship: participates_in CCO:I0006555 ! tp53-cebpb physical interaction relationship: participates_in CCO:I0007451 ! tp53-lap-1 physical interaction relationship: participates_in CCO:I0019185 ! cebpb-smad4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002349 ! regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0005515 name: 2A5D_HUMAN def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform" [UniProtKB:Q14738] synonym: "PP2A, B subunit, B' delta isoform" EXACT [UniProtKB:Q14738] synonym: "PP2A, B subunit, B56 delta isoform" EXACT [UniProtKB:Q14738] synonym: "PP2A, B subunit, PR61 delta isoform" EXACT [UniProtKB:Q14738] synonym: "PP2A, B subunit, R5 delta isoform" EXACT [UniProtKB:Q14738] xref: EMBL:AAB69751.1 xref: EMBL:AAH01095.1 xref: EMBL:AAH01175.1 xref: EMBL:AAH10692.1 xref: EMBL:BAA11372.1 xref: EMBL:BAA20381.1 xref: EMBL:BAA20382.1 xref: EMBL:CAI19791.1 xref: EMBL:EAX04133.1 xref: UniProtKB:O00494 xref: UniProtKB:O00696 xref: UniProtKB:Q14738 xref: UniProtKB:Q15171 xref: UniProtKB:Q5TC39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004000 ! PPP2R5D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006347 ! ppp2r5d-sgol1-1 physical interaction relationship: participates_in CCO:I0006353 ! sgol1-pp2r1b-ppp2r5a physical interaction relationship: participates_in CCO:I0006558 ! ppp2r5a-sgol1-1 physical interaction relationship: participates_in CCO:I0007274 ! nek1-ppp2r5d-1 physical interaction relationship: participates_in CCO:I0007278 ! nek1-tsc2-3 physical interaction relationship: participates_in CCO:I0007513 ! ppp2r5d-cdc25c-1 physical interaction relationship: participates_in CCO:I0015178 ! ppfia1-ppp2r5d physical interaction relationship: participates_in CCO:I0016325 ! ppp2r5d-ppp2r5a-1 physical interaction relationship: participates_in CCO:I0019429 ! ppfia1-ppp2r5d-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010376 ! 2A5D_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0035967 ! 2A5D_HUMAN-Phosphothreonine553 relationship: transforms_into CCO:B0065196 ! 2A5D_HUMAN-Phosphoserine573 [Term] id: CCO:B0005516 name: 2A5A_HUMAN def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform" [UniProtKB:Q15172] synonym: "PP2A, B subunit, B' alpha isoform" EXACT [UniProtKB:Q15172] synonym: "PP2A, B subunit, B56 alpha isoform" EXACT [UniProtKB:Q15172] synonym: "PP2A, B subunit, PR61 alpha isoform" EXACT [UniProtKB:Q15172] synonym: "PP2A, B subunit, R5 alpha isoform" EXACT [UniProtKB:Q15172] xref: EMBL:AAC37601.1 xref: EMBL:AAH22474.1 xref: EMBL:AAI10884.1 xref: EMBL:CAH71821.1 xref: EMBL:CAH73229.1 xref: UniProtKB:Q15172 xref: UniProtKB:Q2NL72 xref: UniProtKB:Q5VVB2 xref: UniProtKB:Q8TBI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0003999 ! PPP2R5A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006348 ! ppp2r5a-sgol2-2 physical interaction relationship: participates_in CCO:I0006353 ! sgol1-pp2r1b-ppp2r5a physical interaction relationship: participates_in CCO:I0006558 ! ppp2r5a-sgol1-1 physical interaction relationship: participates_in CCO:I0006760 ! sgol1-ppp2r5a-1 physical interaction relationship: participates_in CCO:I0007297 ! sgol1-ppp2r5a-2 colocalization relationship: participates_in CCO:I0007430 ! gnl3-ppp2r5a-1 physical interaction relationship: participates_in CCO:I0007431 ! ppp2r5a-gnl3 physical interaction relationship: participates_in CCO:I0007962 ! gnl3-ppp2r5a physical interaction relationship: participates_in CCO:I0016325 ! ppp2r5d-ppp2r5a-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065194 ! 2A5A_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0065195 ! 2A5A_HUMAN-Phosphoserine42 [Term] id: CCO:B0005517 name: 2AAB_HUMAN def: "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform" [UniProtKB:P30154] synonym: "PP2A, subunit A, PR65-beta isoform" EXACT [UniProtKB:P30154] synonym: "PP2A, subunit A, R1-beta isoform" EXACT [UniProtKB:P30154] xref: EMBL:AAA59983.1 xref: EMBL:AAC63525.1 xref: EMBL:AAC69624.1 xref: EMBL:AAG39644.1 xref: UniProtKB:O75620 xref: UniProtKB:P30154 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004003 ! PPP2R1B_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006353 ! sgol1-pp2r1b-ppp2r5a physical interaction relationship: participates_in CCO:I0007181 ! snf1l2-2aab-1 physical interaction relationship: participates_in CCO:I0016710 ! map3k3-ppp2r1b physical interaction [Term] id: CCO:B0005518 name: 2A5E_HUMAN def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform" [UniProtKB:Q16537] synonym: "PP2A, B subunit, B' epsilon isoform" EXACT [UniProtKB:Q16537] synonym: "PP2A, B subunit, B56 epsilon isoform" EXACT [UniProtKB:Q16537] synonym: "PP2A, B subunit, PR61 epsilon isoform" EXACT [UniProtKB:Q16537] synonym: "PP2A, B subunit, R5 epsilon isoform" EXACT [UniProtKB:Q16537] xref: EMBL:AAB69752.1 xref: EMBL:AAH93766.1 xref: EMBL:CAA93153.1 xref: UniProtKB:Q16537 xref: UniProtKB:Q52LW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004001 ! PPP2R5E_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006353 ! sgol1-pp2r1b-ppp2r5a physical interaction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005519 name: SET_HUMAN def: "Protein SET" [UniProtKB:Q01105] synonym: "HLA-DR-associated protein II" EXACT [UniProtKB:Q01105] synonym: "I-2PP2A" EXACT [UniProtKB:Q01105] synonym: "IGAAD" EXACT [UniProtKB:Q01105] synonym: "Inhibitor of granzyme A-activated DNase" EXACT [UniProtKB:Q01105] synonym: "PHAPII" EXACT [UniProtKB:Q01105] synonym: "Phosphatase 2A inhibitor I2PP2A" EXACT [UniProtKB:Q01105] synonym: "TAF-I" EXACT [UniProtKB:Q01105] synonym: "Template-activating factor I" EXACT [UniProtKB:Q01105] xref: EMBL:AAA60318.1 xref: EMBL:AAC50460.1 xref: EMBL:AAH32749.1 xref: EMBL:AAQ79833.1 xref: EMBL:ABP96841.1 xref: EMBL:BAA08139.1 xref: EMBL:BAD97276.1 xref: EMBL:CAA52982.1 xref: EMBL:CAG38780.1 xref: EMBL:CAG46847.1 xref: EMBL:CAH71410.1 xref: UniProtKB:A5A5H4 xref: UniProtKB:Q01105 xref: UniProtKB:Q15541 xref: UniProtKB:Q5VXV1 xref: UniProtKB:Q6FHZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005598 ! SET_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0006353 ! sgol1-pp2r1b-ppp2r5a physical interaction relationship: participates_in CCO:I0006539 ! cdh1-ctnna1-1 physical interaction relationship: participates_in CCO:I0015088 ! set-thap7 physical interaction relationship: participates_in CCO:I0016531 ! ikbkg-set physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0001990 ! negative regulation of histone acetylation relationship: transforms_into CCO:B0014024 ! SET_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0014025 ! SET_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0031374 ! SET_HUMAN-Phosphotyrosine146 [Term] id: CCO:B0005520 name: M3K8_HUMAN def: "Mitogen-activated protein kinase kinase kinase 8" [UniProtKB:P41279] synonym: "C-COT" EXACT [UniProtKB:P41279] synonym: "Cancer Osaka thyroid oncogene" EXACT [UniProtKB:P41279] synonym: "COT proto-oncogene serine/threonine-protein kinase" EXACT [UniProtKB:P41279] synonym: "EC 2.7.11.25" EXACT [UniProtKB:P41279] synonym: "TPL-2" EXACT [UniProtKB:P41279] synonym: "Tumor progression locus 2" EXACT [UniProtKB:P41279] xref: EMBL:AAG13454.1 xref: EMBL:AAI04834.1 xref: EMBL:AAI13567.1 xref: EMBL:AAP45053.1 xref: EMBL:BAA03387.1 xref: EMBL:CAA78512.1 xref: EMBL:CAI14227.1 xref: UniProtKB:P41279 xref: UniProtKB:Q14275 xref: UniProtKB:Q5T855 xref: UniProtKB:Q9HC81 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005010 ! MAP3K8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006354 ! map3k8-ruvbl1 physical interaction relationship: participates_in CCO:I0016342 ! map3k8-hspa9b physical interaction relationship: participates_in CCO:I0016343 ! map3k8-eef1a2 physical interaction relationship: participates_in CCO:I0016344 ! map3k8-lgals3bp physical interaction relationship: participates_in CCO:I0016345 ! map3k8-nfkb2 physical interaction relationship: participates_in CCO:I0016346 ! map3k8-sptbn1 physical interaction relationship: participates_in CCO:I0016347 ! map3k8-hspca physical interaction relationship: participates_in CCO:I0017154 ! map3k8-nfkb1 physical interaction relationship: participates_in CCO:I0017156 ! rel-map3k8 physical interaction relationship: participates_in CCO:I0017188 ! nfkb2-map3k8 physical interaction relationship: transforms_into CCO:B0067820 ! M3K8_HUMAN-Phosphoserine141 [Term] id: CCO:B0005521 name: IKBA_HUMAN def: "NF-kappa-B inhibitor alpha" [UniProtKB:P25963] synonym: "I-kappa-B-alpha" EXACT [UniProtKB:P25963] synonym: "IkappaBalpha" EXACT [UniProtKB:P25963] synonym: "IkB-alpha" EXACT [UniProtKB:P25963] synonym: "Major histocompatibility complex enhancer-binding protein MAD3" EXACT [UniProtKB:P25963] xref: EMBL:AAA16489.1 xref: EMBL:AAH02601.1 xref: EMBL:AAH04983.1 xref: EMBL:AAK51149.1 xref: EMBL:AAP35754.1 xref: EMBL:AAR29599.1 xref: EMBL:CAB65556.2 xref: UniProtKB:P25963 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004871 ! NFKBIA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006355 ! nfkbia-mcm3 physical interaction relationship: participates_in CCO:I0006356 ! nfkbia-anxa1 physical interaction relationship: participates_in CCO:I0006423 ! nfkbia-mcm5 physical interaction relationship: participates_in CCO:I0006424 ! nfkbia-mcm7 physical interaction relationship: participates_in CCO:I0015670 ! nfkbia-pom121 physical interaction relationship: participates_in CCO:I0016356 ! rel-nfkbia physical interaction relationship: participates_in CCO:I0016369 ! nfkbia-hspa1l physical interaction relationship: participates_in CCO:I0016370 ! nfkbia-hspa5 physical interaction relationship: participates_in CCO:I0016371 ! nfkbia-hspa8 physical interaction relationship: participates_in CCO:I0016372 ! nfkbia-slc25a5 physical interaction relationship: participates_in CCO:I0016373 ! nfkbia-hspa9b physical interaction relationship: participates_in CCO:I0016374 ! nfkbia-rpl23 physical interaction relationship: participates_in CCO:I0016375 ! nfkbia-polrmt physical interaction relationship: participates_in CCO:I0016376 ! nfkbia-nfkbia physical interaction relationship: participates_in CCO:I0016377 ! nfkbia-nfkb1 physical interaction relationship: participates_in CCO:I0016378 ! nfkbia-actg1 physical interaction relationship: participates_in CCO:I0016379 ! nfkbia-vcp physical interaction relationship: participates_in CCO:I0016380 ! nfkbia-cltc physical interaction relationship: participates_in CCO:I0016381 ! nfkbia-hsp70_1 physical interaction relationship: participates_in CCO:I0016382 ! nfkbia-sprr3 physical interaction relationship: participates_in CCO:I0016383 ! nfkbia-nfkb2 physical interaction relationship: participates_in CCO:I0016384 ! nfkbia-tuba2 physical interaction relationship: participates_in CCO:I0016385 ! nfkbia-ptpn13 physical interaction relationship: participates_in CCO:I0016386 ! nfkbia-tuba1 physical interaction relationship: participates_in CCO:I0016867 ! relb-nfkbia physical interaction relationship: participates_in CCO:I0017158 ! nfkbia-fbxw1b-1 physical interaction relationship: participates_in CCO:I0017159 ! nfkbia-rel physical interaction relationship: participates_in CCO:I0017160 ! nfkbia-nfkbib physical interaction relationship: participates_in CCO:I0017161 ! nfkbia-ikbkap physical interaction relationship: participates_in CCO:I0017162 ! nfkbia-chuk physical interaction relationship: participates_in CCO:I0017163 ! nfkbia-ikbkb physical interaction relationship: participates_in CCO:I0017164 ! nfkbia-ikbkg physical interaction relationship: participates_in CCO:I0017193 ! nfkb2-nfkbia-1 physical interaction relationship: participates_in CCO:I0017787 ! nfkb1-nfkbia-1 physical interaction relationship: participates_in CCO:I0018628 ! chuk-nfkbia-1 phosphorylation relationship: participates_in CCO:I0018629 ! ikbkb-nfkbia-2 phosphorylation relationship: participates_in CCO:I0019517 ! ikbkb-nfkbia-3 phosphorylation relationship: participates_in CCO:P0000771 ! cytoplasmic sequestering of NF-kappaB relationship: participates_in CCO:P0001484 ! lipopolysaccharide-mediated signaling pathway relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002452 ! negative regulation of myeloid cell differentiation relationship: participates_in CCO:P0002534 ! negative regulation of Notch signaling pathway relationship: transforms_into CCO:B0012340 ! IKBA_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0012341 ! IKBA_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0012342 ! IKBA_HUMAN-Phosphotyrosine42 relationship: transforms_into CCO:B0041145 ! IKBA_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0041146 ! IKBA_HUMAN-Phosphoserine288 relationship: transforms_into CCO:B0041147 ! IKBA_HUMAN-Phosphothreonine291 relationship: transforms_into CCO:B0041148 ! IKBA_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0041149 ! IKBA_HUMAN-Phosphothreonine299 [Term] id: CCO:B0005522 name: IKKB_HUMAN def: "Inhibitor of nuclear factor kappa-B kinase subunit beta" [UniProtKB:O14920] synonym: "EC 2.7.11.10" EXACT [UniProtKB:O14920] synonym: "I-kappa-B kinase 2" EXACT [UniProtKB:O14920] synonym: "I-kappa-B-kinase beta" EXACT [UniProtKB:O14920] synonym: "IkBKB" EXACT [UniProtKB:O14920] synonym: "IKK-B" EXACT [UniProtKB:O14920] synonym: "IKK-beta" EXACT [UniProtKB:O14920] synonym: "IKK2" EXACT [UniProtKB:O14920] synonym: "NFKBIKB" EXACT [UniProtKB:O14920] synonym: "Nuclear factor NF-kappa-B inhibitor kinase beta" EXACT [UniProtKB:O14920] xref: EMBL:AAC51860.1 xref: EMBL:AAC64675.1 xref: EMBL:AAD08997.1 xref: EMBL:AAH06231.1 xref: EMBL:AAT65965.1 xref: UniProtKB:O14920 xref: UniProtKB:O75327 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004875 ! IKBKB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006357 ! ikbkb-q9bva1 physical interaction relationship: participates_in CCO:I0006431 ! ikbkb-cdc37 physical interaction relationship: participates_in CCO:I0008543 ! ikbkb-myh10 physical interaction relationship: participates_in CCO:I0016447 ! ikbkb-ikbkg physical interaction relationship: participates_in CCO:I0016448 ! ikbkb-hspa1l physical interaction relationship: participates_in CCO:I0016449 ! ikbkb-hspa5 physical interaction relationship: participates_in CCO:I0016450 ! ikbkb-hspa8 physical interaction relationship: participates_in CCO:I0016451 ! ikbkb-chuk physical interaction relationship: participates_in CCO:I0016452 ! ikbkb-hspa9b physical interaction relationship: participates_in CCO:I0016453 ! ikbkb-iqgap1 physical interaction relationship: participates_in CCO:I0016454 ! ikbkb-eprs physical interaction relationship: participates_in CCO:I0016455 ! ikbkb-c1qbp physical interaction relationship: participates_in CCO:I0016456 ! ikbkb-baf155 physical interaction relationship: participates_in CCO:I0016457 ! ikbkb-lyz physical interaction relationship: participates_in CCO:I0016458 ! ikbkb-actg1 physical interaction relationship: participates_in CCO:I0016459 ! ikbkb-cltc physical interaction relationship: participates_in CCO:I0016460 ! ikbkb-ikbkb physical interaction relationship: participates_in CCO:I0016461 ! ikbkb-hsp70_1 physical interaction relationship: participates_in CCO:I0016462 ! ikbkb-flna physical interaction relationship: participates_in CCO:I0016463 ! ikbkb-hnrpu physical interaction relationship: participates_in CCO:I0016464 ! ikbkb-adprt physical interaction relationship: participates_in CCO:I0016465 ! ikbkb-tuba2 physical interaction relationship: participates_in CCO:I0016709 ! map3k3-ikbkb physical interaction relationship: participates_in CCO:I0016802 ! nfkb2-ikbkb physical interaction relationship: participates_in CCO:I0017163 ! nfkbia-ikbkb physical interaction relationship: participates_in CCO:I0017169 ! nfkbib-ikbkb physical interaction relationship: participates_in CCO:I0017208 ! chuk-ikbkb physical interaction relationship: participates_in CCO:I0017209 ! ikbkb-hspca physical interaction relationship: participates_in CCO:I0017210 ! ikbkb-hspcb physical interaction relationship: participates_in CCO:I0017211 ! ikbkb-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0017220 ! ikbkg-ikbkb physical interaction relationship: participates_in CCO:I0017244 ! map3k14-ikbkb physical interaction relationship: participates_in CCO:I0017310 ! ikbkb-ncoa3-2 physical interaction relationship: participates_in CCO:I0017388 ! ikbkb-ikbkg-2 physical interaction relationship: participates_in CCO:I0017703 ! ikk_gamma-ikk_beta physical interaction relationship: participates_in CCO:I0017783 ! ikbkb-mavs-1 physical interaction relationship: participates_in CCO:I0018043 ! ikk_complex physical interaction relationship: participates_in CCO:I0018211 ! ncoa3-crebbp-ncoa2-1 physical interaction relationship: participates_in CCO:I0018212 ! ncoa3-ikbkb physical interaction relationship: participates_in CCO:I0018241 ! ikbkb-nfkbia-5 physical interaction relationship: participates_in CCO:I0018294 ! ncoa3-ikbkb-1 physical interaction relationship: participates_in CCO:I0018385 ! ikbkb-4 physical interaction relationship: participates_in CCO:I0018386 ! ikbkb-5 physical interaction relationship: participates_in CCO:I0018387 ! ikbkb-nfkbia-4 physical interaction relationship: participates_in CCO:I0018498 ! ikk_gamma-ikk_beta-1 physical interaction relationship: participates_in CCO:I0018629 ! ikbkb-nfkbia-2 phosphorylation relationship: participates_in CCO:I0018630 ! ikbkb-chuk-1 physical interaction relationship: participates_in CCO:I0018632 ! ikbkb-map3k1-1 phosphorylation relationship: participates_in CCO:I0018671 ! ikka-src-2 physical interaction relationship: participates_in CCO:I0018672 ! ikka-src-1 physical interaction relationship: participates_in CCO:I0019517 ! ikbkb-nfkbia-3 phosphorylation relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0012349 ! IKKB_HUMAN-Phosphothreonine23 relationship: transforms_into CCO:B0012350 ! IKKB_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0012351 ! IKKB_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0012352 ! IKKB_HUMAN-Phosphoserine670 relationship: transforms_into CCO:B0012353 ! IKKB_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0012354 ! IKKB_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0012355 ! IKKB_HUMAN-Phosphoserine682 relationship: transforms_into CCO:B0012356 ! IKKB_HUMAN-Phosphoserine689 relationship: transforms_into CCO:B0012357 ! IKKB_HUMAN-Phosphoserine692 relationship: transforms_into CCO:B0012358 ! IKKB_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0012359 ! IKKB_HUMAN-Phosphoserine697 relationship: transforms_into CCO:B0012360 ! IKKB_HUMAN-Phosphoserine705 relationship: transforms_into CCO:B0012361 ! IKKB_HUMAN-Phosphoserine733 relationship: transforms_into CCO:B0012362 ! IKKB_HUMAN-Phosphoserine740 relationship: transforms_into CCO:B0012363 ! IKKB_HUMAN-Phosphoserine750 relationship: transforms_into CCO:B0041152 ! IKKB_HUMAN-S-nitrosocysteine179 [Term] id: CCO:B0005523 name: IKKE_HUMAN def: "Inhibitor of nuclear factor kappa-B kinase subunit epsilon" [UniProtKB:Q14164] synonym: "EC 2.7.11.10" EXACT [UniProtKB:Q14164] synonym: "I kappa-B kinase epsilon" EXACT [UniProtKB:Q14164] synonym: "IkBKE" EXACT [UniProtKB:Q14164] synonym: "IKK-E" EXACT [UniProtKB:Q14164] synonym: "IKK-epsilon" EXACT [UniProtKB:Q14164] synonym: "IKK-i" EXACT [UniProtKB:Q14164] synonym: "Inducible I kappa-B kinase" EXACT [UniProtKB:Q14164] xref: EMBL:AAF45307.1 xref: EMBL:AAI05924.1 xref: EMBL:AAI05925.1 xref: EMBL:ABG25921.1 xref: EMBL:BAA09772.2 xref: EMBL:BAA85155.1 xref: EMBL:CAI15250.1 xref: UniProtKB:Q14164 xref: UniProtKB:Q3KR43 xref: UniProtKB:Q5JTS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004876 ! IKBKE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006358 ! ikbke-kif11 physical interaction relationship: participates_in CCO:I0006359 ! ikbke-ruvbl1 physical interaction relationship: participates_in CCO:I0006432 ! ikbke-cdc37 physical interaction relationship: participates_in CCO:I0008544 ! ikbke-myh10 physical interaction relationship: participates_in CCO:I0016466 ! ikbke-hspa8 physical interaction relationship: participates_in CCO:I0016467 ! ikbke-hspa9b physical interaction relationship: participates_in CCO:I0016468 ! ikbke-cct5 physical interaction relationship: participates_in CCO:I0016469 ! ikbke-o43809 physical interaction relationship: participates_in CCO:I0016470 ! ikbke-hnrph1 physical interaction relationship: participates_in CCO:I0016471 ! ikbke-sptan1 physical interaction relationship: participates_in CCO:I0016472 ! ikbke-actg1 physical interaction relationship: participates_in CCO:I0016473 ! ikbke-tfrc physical interaction relationship: participates_in CCO:I0016474 ! ikbke-lgals3bp physical interaction relationship: participates_in CCO:I0016475 ! ikbke-cltc physical interaction relationship: participates_in CCO:I0016476 ! ikbke-ikbke physical interaction relationship: participates_in CCO:I0016477 ! ikbke-traf2 physical interaction relationship: participates_in CCO:I0016478 ! ikbke-hsp70_1 physical interaction relationship: participates_in CCO:I0016479 ! ikbke-myo6 physical interaction relationship: participates_in CCO:I0016480 ! ikbke-myh9 physical interaction relationship: participates_in CCO:I0016481 ! ikbke-sptbn1 physical interaction relationship: participates_in CCO:I0016482 ! ikbke-dsp physical interaction relationship: participates_in CCO:I0016483 ! ikbke-tpm3 physical interaction relationship: participates_in CCO:I0016484 ! ikbke-myl6 physical interaction relationship: participates_in CCO:I0016485 ! ikbke-tuba2 physical interaction relationship: participates_in CCO:I0016486 ! ikbke-mlcb physical interaction relationship: participates_in CCO:I0017212 ! ikbke-fkbp5 physical interaction relationship: participates_in CCO:I0017213 ! ikbke-hspca physical interaction relationship: participates_in CCO:I0017214 ! ikbke-hspcb physical interaction relationship: participates_in CCO:I0017215 ! ikbke-ktn1 physical interaction relationship: participates_in CCO:I0017781 ! ikbke-mavs-1 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0012364 ! IKKE_HUMAN-Phosphoserine172 [Term] id: CCO:B0005524 name: NEMO_HUMAN def: "NF-kappa-B essential modulator" [UniProtKB:Q9Y6K9] synonym: "FIP-3" EXACT [UniProtKB:Q9Y6K9] synonym: "I-kappa-B kinase gamma" EXACT [UniProtKB:Q9Y6K9] synonym: "IkB kinase subunit gamma" EXACT [UniProtKB:Q9Y6K9] synonym: "IkB kinase-associated protein 1" EXACT [UniProtKB:Q9Y6K9] synonym: "IKK-gamma" EXACT [UniProtKB:Q9Y6K9] synonym: "IKKAP1" EXACT [UniProtKB:Q9Y6K9] synonym: "IKKG" EXACT [UniProtKB:Q9Y6K9] synonym: "Inhibitor of nuclear factor kappa-B kinase subunit gamma" EXACT [UniProtKB:Q9Y6K9] synonym: "NEMO" EXACT [UniProtKB:Q9Y6K9] synonym: "NF-kappa-B essential modifier" EXACT [UniProtKB:Q9Y6K9] xref: EMBL:AAC36330.1 xref: EMBL:AAD12183.1 xref: EMBL:AAD38081.1 xref: EMBL:AAF99679.1 xref: EMBL:AAH00299.1 xref: EMBL:AAH12114.1 xref: EMBL:AAH50612.1 xref: EMBL:AAV38427.1 xref: EMBL:CAB93146.1 xref: UniProtKB:Q9Y6K9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005183 ! IKBKG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006360 ! ikbkg-smc2l1 physical interaction relationship: participates_in CCO:I0006361 ! ikbkg-msh2 physical interaction relationship: participates_in CCO:I0006362 ! ikbkg-mcm7 physical interaction relationship: participates_in CCO:I0006363 ! ikbkg-dnch1 physical interaction relationship: participates_in CCO:I0006364 ! ikbkg-smc4l1 physical interaction relationship: participates_in CCO:I0006365 ! ikbkg-q8ix12 physical interaction relationship: participates_in CCO:I0006366 ! ikbkg-ppp1cc physical interaction relationship: participates_in CCO:I0006367 ! ikbkg-ppp1cb physical interaction relationship: participates_in CCO:I0006433 ! ikbkg-cdc37 physical interaction relationship: participates_in CCO:I0008518 ! ikbkg-ddb1 physical interaction relationship: participates_in CCO:I0008545 ! ikbkg-myh10 physical interaction relationship: participates_in CCO:I0008963 ! ikbkg-rps15a physical interaction relationship: participates_in CCO:I0015930 ! ikbkg-chuk-3 physical interaction relationship: participates_in CCO:I0015931 ! ikbkg-chuk-1 physical interaction relationship: participates_in CCO:I0016271 ! ikk-csn3 physical interaction relationship: participates_in CCO:I0016422 ! nfkbie-ikbkg physical interaction relationship: participates_in CCO:I0016431 ! chuk-ikbkg physical interaction relationship: participates_in CCO:I0016447 ! ikbkb-ikbkg physical interaction relationship: participates_in CCO:I0016487 ! ikbkg-vars2 physical interaction relationship: participates_in CCO:I0016488 ! ikbkg-lrpprc physical interaction relationship: participates_in CCO:I0016489 ! ikbkg-ikbkg physical interaction relationship: participates_in CCO:I0016490 ! ikbkg-hspa1l physical interaction relationship: participates_in CCO:I0016491 ! ikbkg-hspa5 physical interaction relationship: participates_in CCO:I0016492 ! ikbkg-dbn1 physical interaction relationship: participates_in CCO:I0016493 ! ikbkg-ighg3 physical interaction relationship: participates_in CCO:I0016494 ! ikbkg-rars physical interaction relationship: participates_in CCO:I0016495 ! ikbkg-capza1 physical interaction relationship: participates_in CCO:I0016496 ! ikbkg-slc25a5 physical interaction relationship: participates_in CCO:I0016497 ! ikbkg-atp5o physical interaction relationship: participates_in CCO:I0016498 ! ikbkg-hspa9b physical interaction relationship: participates_in CCO:I0016499 ! ikbkg-mars physical interaction relationship: participates_in CCO:I0016500 ! ikbkg-rps5 physical interaction relationship: participates_in CCO:I0016501 ! ikbkg-rps10 physical interaction relationship: participates_in CCO:I0016502 ! ikbkg-rplp2 physical interaction relationship: participates_in CCO:I0016503 ! ikbkg-sfxn1 physical interaction relationship: participates_in CCO:I0016504 ! ikbkg-crm1 physical interaction relationship: participates_in CCO:I0016505 ! ikbkg-rpl23 physical interaction relationship: participates_in CCO:I0016506 ! ikbkg-myo1c physical interaction relationship: participates_in CCO:I0016507 ! ikbkg-eppk1 physical interaction relationship: participates_in CCO:I0016508 ! ikbkg-rps3 physical interaction relationship: participates_in CCO:I0016509 ! ikbkg-trim28 physical interaction relationship: participates_in CCO:I0016510 ! ikbkg-hspa6 physical interaction relationship: participates_in CCO:I0016511 ! ikbkg-rps20 physical interaction relationship: participates_in CCO:I0016512 ! ikbkg-kif5b physical interaction relationship: participates_in CCO:I0016513 ! ikbkg-iars physical interaction relationship: participates_in CCO:I0016514 ! ikbkg-gnb2l1 physical interaction relationship: participates_in CCO:I0016515 ! ikbkg-eef1a2 physical interaction relationship: participates_in CCO:I0016516 ! ikbkg-q9h853 physical interaction relationship: participates_in CCO:I0016517 ! ikbkg-dap3 physical interaction relationship: participates_in CCO:I0016518 ! ikbkg-q9bzt1 physical interaction relationship: participates_in CCO:I0016519 ! ikbkg-cad physical interaction relationship: participates_in CCO:I0016520 ! ikbkg-canx physical interaction relationship: participates_in CCO:I0016521 ! ikbkg-actg1 physical interaction relationship: participates_in CCO:I0016522 ! ikbkg-q9bsj8 physical interaction relationship: participates_in CCO:I0016523 ! ikbkg-cltc physical interaction relationship: participates_in CCO:I0016524 ! ikbkg-rpn1 physical interaction relationship: participates_in CCO:I0016525 ! ikbkg-rps14 physical interaction relationship: participates_in CCO:I0016526 ! ikbkg-f7 physical interaction relationship: participates_in CCO:I0016527 ! ikbkg-idh3a physical interaction relationship: participates_in CCO:I0016528 ! ikbkg-hsp70_1 physical interaction relationship: participates_in CCO:I0016529 ! ikbkg-hspa8 physical interaction relationship: participates_in CCO:I0016530 ! ikbkg-myo6 physical interaction relationship: participates_in CCO:I0016531 ! ikbkg-set physical interaction relationship: participates_in CCO:I0016532 ! ikbkg-q96ri3 physical interaction relationship: participates_in CCO:I0016533 ! ikbkg-drim physical interaction relationship: participates_in CCO:I0016534 ! ikbkg-rplp0 physical interaction relationship: participates_in CCO:I0016535 ! ikbkg-psmd13 physical interaction relationship: participates_in CCO:I0016536 ! ikbkg-kiaa1352 physical interaction relationship: participates_in CCO:I0016537 ! ikbkg-ighg1 physical interaction relationship: participates_in CCO:I0016538 ! ikbkg-ikbkg-1 physical interaction relationship: participates_in CCO:I0016539 ! ikbkg-q86tt2 physical interaction relationship: participates_in CCO:I0016540 ! ikbkg-q8n4y9 physical interaction relationship: participates_in CCO:I0016541 ! ikbkg-q8nhw5 physical interaction relationship: participates_in CCO:I0016542 ! ikbkg-vdp physical interaction relationship: participates_in CCO:I0016543 ! ikbkg-ywhaz physical interaction relationship: participates_in CCO:I0016544 ! ikbkg-flna physical interaction relationship: participates_in CCO:I0016545 ! ikbkg-ipo7 physical interaction relationship: participates_in CCO:I0016546 ! ikbkg-usp18 physical interaction relationship: participates_in CCO:I0016547 ! ikbkg-kiaa0219 physical interaction relationship: participates_in CCO:I0016548 ! ikbkg-myh9 physical interaction relationship: participates_in CCO:I0016549 ! ikbkg-hnrpu physical interaction relationship: participates_in CCO:I0016550 ! ikbkg-atp5b physical interaction relationship: participates_in CCO:I0016551 ! ikbkg-tuba8 physical interaction relationship: participates_in CCO:I0016552 ! ikbkg-vim physical interaction relationship: participates_in CCO:I0016553 ! ikbkg-adprt physical interaction relationship: participates_in CCO:I0016554 ! ikbkg-slc25a6 physical interaction relationship: participates_in CCO:I0016555 ! ikbkg-copa physical interaction relationship: participates_in CCO:I0016556 ! ikbkg-gart physical interaction relationship: participates_in CCO:I0016557 ! ikbkg-prkdc physical interaction relationship: participates_in CCO:I0016558 ! ikbkg-myl6 physical interaction relationship: participates_in CCO:I0016559 ! ikbkg-xpo7 physical interaction relationship: participates_in CCO:I0016560 ! ikbkg-tuba2 physical interaction relationship: participates_in CCO:I0016561 ! ikbkg-rps3a physical interaction relationship: participates_in CCO:I0016562 ! ikbkg-cse1l physical interaction relationship: participates_in CCO:I0016563 ! ikbkg-ipo9 physical interaction relationship: participates_in CCO:I0016564 ! ikbkg-mlcb physical interaction relationship: participates_in CCO:I0016565 ! ikbkg-hspd1 physical interaction relationship: participates_in CCO:I0016566 ! ikbkg-rps16 physical interaction relationship: participates_in CCO:I0016567 ! ikbkg-rps27 physical interaction relationship: participates_in CCO:I0016568 ! ikbkg-myo1d physical interaction relationship: participates_in CCO:I0016569 ! ikbkg-tuba1 physical interaction relationship: participates_in CCO:I0016662 ! map3k3-ikbkg physical interaction relationship: participates_in CCO:I0017164 ! nfkbia-ikbkg physical interaction relationship: participates_in CCO:I0017170 ! nfkbib-ikbkg physical interaction relationship: participates_in CCO:I0017196 ! nfkb2-ikbkg-2 physical interaction relationship: participates_in CCO:I0017216 ! ikbkg-q9nwg8 physical interaction relationship: participates_in CCO:I0017217 ! ikbkg-hspca physical interaction relationship: participates_in CCO:I0017218 ! ikbkg-hspcb physical interaction relationship: participates_in CCO:I0017219 ! ikbkg-chuk physical interaction relationship: participates_in CCO:I0017220 ! ikbkg-ikbkb physical interaction relationship: participates_in CCO:I0017221 ! ikbkg-il14 physical interaction relationship: participates_in CCO:I0017222 ! ikbkg-tbk1 physical interaction relationship: participates_in CCO:I0017245 ! map3k14-ikbkg physical interaction relationship: participates_in CCO:I0017702 ! ikk_gamma-ikk_alpha physical interaction relationship: participates_in CCO:I0017703 ! ikk_gamma-ikk_beta physical interaction relationship: participates_in CCO:I0018043 ! ikk_complex physical interaction relationship: participates_in CCO:I0018211 ! ncoa3-crebbp-ncoa2-1 physical interaction relationship: participates_in CCO:I0018241 ! ikbkb-nfkbia-5 physical interaction relationship: participates_in CCO:I0018356 ! ncoa3-ikbkg-1 physical interaction relationship: participates_in CCO:I0018387 ! ikbkb-nfkbia-4 physical interaction relationship: participates_in CCO:I0018497 ! ikbkg-chuk-2 physical interaction relationship: participates_in CCO:I0018498 ! ikk_gamma-ikk_beta-1 physical interaction relationship: participates_in CCO:I0018671 ! ikka-src-2 physical interaction relationship: participates_in CCO:I0018672 ! ikka-src-1 physical interaction relationship: participates_in CCO:I0018798 ! ikk-csn3-1 physical interaction relationship: participates_in CCO:I0019263 ! ikka-src-3 physical interaction relationship: participates_in CCO:I0019517 ! ikbkb-nfkbia-3 phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: transforms_into CCO:B0041163 ! NEMO_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0041164 ! NEMO_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0041165 ! NEMO_HUMAN-Phosphoserine68 relationship: transforms_into CCO:B0041166 ! NEMO_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0041167 ! NEMO_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0068574 ! NEMO_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0068575 ! NEMO_HUMAN-Phosphoserine387 [Term] id: CCO:B0005525 name: M3K1_HUMAN def: "Mitogen-activated protein kinase kinase kinase 1" [UniProtKB:Q13233] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q13233] synonym: "MAPK/ERK kinase kinase 1" EXACT [UniProtKB:Q13233] synonym: "MEK kinase 1" EXACT [UniProtKB:Q13233] synonym: "MEKK 1" EXACT [UniProtKB:Q13233] xref: EMBL:AAB05828.1 xref: EMBL:AAC97073.1 xref: UniProtKB:Q13233 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005006 ! MAP3K1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006368 ! map3k1-q9bva1 physical interaction relationship: participates_in CCO:I0006369 ! map3k1-nol1 physical interaction relationship: participates_in CCO:I0006370 ! map3k1-rps4x physical interaction relationship: participates_in CCO:I0006371 ! map3k1-cct4 physical interaction relationship: participates_in CCO:I0006434 ! map3k1-cdc37 physical interaction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0008519 ! map3k1-ddb1 physical interaction relationship: participates_in CCO:I0008546 ! map3k1-myh10 physical interaction relationship: participates_in CCO:I0015898 ! map3k1-map2k4-1 physical interaction relationship: participates_in CCO:I0015921 ! map4k2-mekk1-2 physical interaction relationship: participates_in CCO:I0015950 ! map4k2-mekk1-1 physical interaction relationship: participates_in CCO:I0016589 ! map3k1-bag2 physical interaction relationship: participates_in CCO:I0016590 ! map3k1-pdcd8 physical interaction relationship: participates_in CCO:I0016591 ! map3k1-ywhae physical interaction relationship: participates_in CCO:I0016592 ! map3k1-hspa1l physical interaction relationship: participates_in CCO:I0016593 ! map3k1-cct8 physical interaction relationship: participates_in CCO:I0016594 ! map3k1-hspa5 physical interaction relationship: participates_in CCO:I0016595 ! map3k1-hspa8 physical interaction relationship: participates_in CCO:I0016596 ! map3k1-slc25a5 physical interaction relationship: participates_in CCO:I0016597 ! map3k1-bag5 physical interaction relationship: participates_in CCO:I0016598 ! map3k1-hspa9b physical interaction relationship: participates_in CCO:I0016599 ! map3k1-mars physical interaction relationship: participates_in CCO:I0016600 ! map3k1-rplp2 physical interaction relationship: participates_in CCO:I0016601 ! map3k1-ruvbl2 physical interaction relationship: participates_in CCO:I0016602 ! map3k1-cct5 physical interaction relationship: participates_in CCO:I0016603 ! map3k1-eppk1 physical interaction relationship: participates_in CCO:I0016604 ! map3k1-map3k1 physical interaction relationship: participates_in CCO:I0016605 ! map3k1-hspa6 physical interaction relationship: participates_in CCO:I0016606 ! map3k1-dnaja1 physical interaction relationship: participates_in CCO:I0016607 ! map3k1-eef1a2 physical interaction relationship: participates_in CCO:I0016608 ! map3k1-glud1 physical interaction relationship: participates_in CCO:I0016609 ! map3k1-cct1 physical interaction relationship: participates_in CCO:I0016610 ! map3k1-ssr4 physical interaction relationship: participates_in CCO:I0016611 ! map3k1-slc1a5 physical interaction relationship: participates_in CCO:I0016612 ! map3k1-cad physical interaction relationship: participates_in CCO:I0016613 ! map3k1-da24a23_2 physical interaction relationship: participates_in CCO:I0016614 ! map3k1-actg1 physical interaction relationship: participates_in CCO:I0016615 ! map3k1-rps6 physical interaction relationship: participates_in CCO:I0016616 ! map3k1-rpl3 physical interaction relationship: participates_in CCO:I0016617 ! map3k1-hadhb physical interaction relationship: participates_in CCO:I0016618 ! map3k1-lgals3bp physical interaction relationship: participates_in CCO:I0016619 ! map3k1-rps11 physical interaction relationship: participates_in CCO:I0016620 ! map3k1-rps14 physical interaction relationship: participates_in CCO:I0016621 ! map3k1-fasn physical interaction relationship: participates_in CCO:I0016622 ! map3k1-cct3 physical interaction relationship: participates_in CCO:I0016623 ! map3k1-cct6a physical interaction relationship: participates_in CCO:I0016624 ! map3k1-gemin4 physical interaction relationship: participates_in CCO:I0016625 ! map3k1-rcn2 physical interaction relationship: participates_in CCO:I0016626 ! map3k1-rpl35a physical interaction relationship: participates_in CCO:I0016627 ! map3k1-rpl7 physical interaction relationship: participates_in CCO:I0016628 ! map3k1-hadha physical interaction relationship: participates_in CCO:I0016629 ! map3k1-hsp70_1 physical interaction relationship: participates_in CCO:I0016630 ! map3k1-q9buf5 physical interaction relationship: participates_in CCO:I0016631 ! map3k1-rpl14 physical interaction relationship: participates_in CCO:I0016632 ! map3k1-q9nzl4 physical interaction relationship: participates_in CCO:I0016633 ! map3k1-rps27 physical interaction relationship: participates_in CCO:I0016634 ! map3k1-q8nhw5 physical interaction relationship: participates_in CCO:I0016635 ! map3k1-dnaja3 physical interaction relationship: participates_in CCO:I0016636 ! map3k1-flna physical interaction relationship: participates_in CCO:I0016637 ! map3k1-dhx9 physical interaction relationship: participates_in CCO:I0016638 ! map3k1-rpl18 physical interaction relationship: participates_in CCO:I0016639 ! map3k1-rpl37a physical interaction relationship: participates_in CCO:I0016640 ! map3k1-vim physical interaction relationship: participates_in CCO:I0016641 ! map3k1-h4f2 physical interaction relationship: participates_in CCO:I0016642 ! map3k1-rps8 physical interaction relationship: participates_in CCO:I0016643 ! map3k1-slc25a6 physical interaction relationship: participates_in CCO:I0016644 ! map3k1-ncl physical interaction relationship: participates_in CCO:I0016645 ! map3k1-rps23 physical interaction relationship: participates_in CCO:I0016646 ! map3k1-rpl35 physical interaction relationship: participates_in CCO:I0016647 ! map3k1-hsph1 physical interaction relationship: participates_in CCO:I0016648 ! map3k1-tuba2 physical interaction relationship: participates_in CCO:I0016649 ! map3k1-rpl13 physical interaction relationship: participates_in CCO:I0016650 ! map3k1-rpl10 physical interaction relationship: participates_in CCO:I0016651 ! map3k1-rpl24 physical interaction relationship: participates_in CCO:I0016652 ! map3k1-snrpf physical interaction relationship: participates_in CCO:I0016653 ! map3k1-usp9x physical interaction relationship: participates_in CCO:I0016654 ! map3k1-rps9 physical interaction relationship: participates_in CCO:I0016655 ! map3k1-rps16 physical interaction relationship: participates_in CCO:I0016656 ! map3k1-mylk2 physical interaction relationship: participates_in CCO:I0016657 ! map3k1-myo1d physical interaction relationship: participates_in CCO:I0016658 ! map3k1-tuba1 physical interaction relationship: participates_in CCO:I0017225 ! map3k1-fkbp5 physical interaction relationship: participates_in CCO:I0017226 ! map3k1-han11 physical interaction relationship: participates_in CCO:I0017227 ! map3k1-hspca physical interaction relationship: participates_in CCO:I0017228 ! map3k1-hspcb physical interaction relationship: participates_in CCO:I0017229 ! map3k1-rpl4 physical interaction relationship: participates_in CCO:I0017230 ! map3k1-rps13 physical interaction relationship: participates_in CCO:I0017417 ! traf2-mekk1 physical interaction relationship: participates_in CCO:I0017631 ! npm_alk-pkc physical interaction relationship: participates_in CCO:I0017639 ! map3k1-npm_alk physical interaction relationship: participates_in CCO:I0018004 ! map3k1-map2k4-3 physical interaction relationship: participates_in CCO:I0018590 ! map3k1-map2k4-2 phosphorylation relationship: participates_in CCO:I0018632 ! ikbkb-map3k1-1 phosphorylation relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0012731 ! M3K1_HUMAN-Phosphothreonine1402 relationship: transforms_into CCO:B0012732 ! M3K1_HUMAN-Phosphothreonine1414 relationship: transforms_into CCO:B0036011 ! M3K1_HUMAN-Phosphothreonine657 relationship: transforms_into CCO:B0036012 ! M3K1_HUMAN-Phosphothreonine665 relationship: transforms_into CCO:B0048312 ! M3K1_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0067806 ! M3K1_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0067807 ! M3K1_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0067808 ! M3K1_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0067809 ! M3K1_HUMAN-Phosphoserine511 relationship: transforms_into CCO:B0067810 ! M3K1_HUMAN-Phosphoserine1020 [Term] id: CCO:B0005526 name: M3K3_HUMAN def: "Mitogen-activated protein kinase kinase kinase 3" [UniProtKB:Q99759] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q99759] synonym: "MAPK/ERK kinase kinase 3" EXACT [UniProtKB:Q99759] synonym: "MEK kinase 3" EXACT [UniProtKB:Q99759] synonym: "MEKK 3" EXACT [UniProtKB:Q99759] xref: EMBL:AAB41729.1 xref: EMBL:AAH90859.1 xref: EMBL:AAH93672.1 xref: EMBL:AAH93674.1 xref: EMBL:EAW94298.1 xref: UniProtKB:Q5BKZ6 xref: UniProtKB:Q99759 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005007 ! MAP3K3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006372 ! map3k3-pfdn1 physical interaction relationship: participates_in CCO:I0006373 ! map3k3-hspa2 physical interaction relationship: participates_in CCO:I0006374 ! map3k3-sugt1 physical interaction relationship: participates_in CCO:I0006375 ! map3k3-mcc physical interaction relationship: participates_in CCO:I0006376 ! map3k3-actn4 physical interaction relationship: participates_in CCO:I0006377 ! map3k3-cct7 physical interaction relationship: participates_in CCO:I0006378 ! map3k3-ruvbl1 physical interaction relationship: participates_in CCO:I0006379 ! map3k3-ppp1ca physical interaction relationship: participates_in CCO:I0006380 ! map3k3-q9bva1 physical interaction relationship: participates_in CCO:I0006381 ! map3k3-nudc physical interaction relationship: participates_in CCO:I0006382 ! map3k3-ppp2r1a physical interaction relationship: participates_in CCO:I0006383 ! map3k3-tubb4 physical interaction relationship: participates_in CCO:I0006384 ! map3k3-cct2 physical interaction relationship: participates_in CCO:I0006385 ! map3k3-ppp1cc physical interaction relationship: participates_in CCO:I0006386 ! map3k3-dlg1 physical interaction relationship: participates_in CCO:I0006387 ! map3k3-cct4 physical interaction relationship: participates_in CCO:I0006435 ! map3k3-ywhaq physical interaction relationship: participates_in CCO:I0006436 ! map3k3-cdc37 physical interaction relationship: participates_in CCO:I0008520 ! map3k3-ddb1 physical interaction relationship: participates_in CCO:I0008547 ! map3k3-myh10 physical interaction relationship: participates_in CCO:I0016659 ! map3k3-bag2 physical interaction relationship: participates_in CCO:I0016660 ! map3k3-pdcd8 physical interaction relationship: participates_in CCO:I0016661 ! map3k3-q9h6t3 physical interaction relationship: participates_in CCO:I0016662 ! map3k3-ikbkg physical interaction relationship: participates_in CCO:I0016663 ! map3k3-scin physical interaction relationship: participates_in CCO:I0016664 ! map3k3-hspa1l physical interaction relationship: participates_in CCO:I0016665 ! map3k3-hspa4 physical interaction relationship: participates_in CCO:I0016666 ! map3k3-cct8 physical interaction relationship: participates_in CCO:I0016667 ! map3k3-gnb2 physical interaction relationship: participates_in CCO:I0016668 ! map3k3-hspa5 physical interaction relationship: participates_in CCO:I0016669 ! map3k3-dbn1 physical interaction relationship: participates_in CCO:I0016670 ! map3k3-dnajb4 physical interaction relationship: participates_in CCO:I0016671 ! map3k3-tmod3 physical interaction relationship: participates_in CCO:I0016672 ! map3k3-chuk physical interaction relationship: participates_in CCO:I0016673 ! map3k3-pfdn6 physical interaction relationship: participates_in CCO:I0016674 ! map3k3-ubl4 physical interaction relationship: participates_in CCO:I0016675 ! map3k3-capza1 physical interaction relationship: participates_in CCO:I0016676 ! map3k3-slc25a5 physical interaction relationship: participates_in CCO:I0016677 ! map3k3-bag5 physical interaction relationship: participates_in CCO:I0016678 ! map3k3-mars physical interaction relationship: participates_in CCO:I0016679 ! map3k3-coro1c physical interaction relationship: participates_in CCO:I0016680 ! map3k3-ruvbl2 physical interaction relationship: participates_in CCO:I0016681 ! map3k3-iqgap1 physical interaction relationship: participates_in CCO:I0016682 ! map3k3-rpl23 physical interaction relationship: participates_in CCO:I0016683 ! map3k3-myo1c physical interaction relationship: participates_in CCO:I0016684 ! map3k3-hs1bp1 physical interaction relationship: participates_in CCO:I0016685 ! map3k3-cct5 physical interaction relationship: participates_in CCO:I0016686 ! map3k3-eppk1 physical interaction relationship: participates_in CCO:I0016687 ! map3k3-phgdh physical interaction relationship: participates_in CCO:I0016688 ! map3k3-hspa6 physical interaction relationship: participates_in CCO:I0016689 ! map3k3-dnaja1 physical interaction relationship: participates_in CCO:I0016690 ! map3k3-iars physical interaction relationship: participates_in CCO:I0016691 ! map3k3-hnrph1 physical interaction relationship: participates_in CCO:I0016692 ! map3k3-myo1b physical interaction relationship: participates_in CCO:I0016693 ! map3k3-c1qbp physical interaction relationship: participates_in CCO:I0016694 ! map3k3-eef1a2 physical interaction relationship: participates_in CCO:I0016695 ! map3k3-sco2 physical interaction relationship: participates_in CCO:I0016696 ! map3k3-sptan1 physical interaction relationship: participates_in CCO:I0016697 ! map3k3-pfdn4 physical interaction relationship: participates_in CCO:I0016698 ! map3k3-dnajb1 physical interaction relationship: participates_in CCO:I0016699 ! map3k3-atp5a1 physical interaction relationship: participates_in CCO:I0016700 ! map3k3-matr3 physical interaction relationship: participates_in CCO:I0016701 ! map3k3-cct1 physical interaction relationship: participates_in CCO:I0016702 ! map3k3-tfg physical interaction relationship: participates_in CCO:I0016703 ! map3k3-cad physical interaction relationship: participates_in CCO:I0016704 ! map3k3-actg1 physical interaction relationship: participates_in CCO:I0016705 ! map3k3-rmp physical interaction relationship: participates_in CCO:I0016706 ! map3k3-vcp physical interaction relationship: participates_in CCO:I0016707 ! map3k3-q92600 physical interaction relationship: participates_in CCO:I0016708 ! map3k3-cltc physical interaction relationship: participates_in CCO:I0016709 ! map3k3-ikbkb physical interaction relationship: participates_in CCO:I0016710 ! map3k3-ppp2r1b physical interaction relationship: participates_in CCO:I0016711 ! map3k3-gnai2 physical interaction relationship: participates_in CCO:I0016712 ! map3k3-capzb physical interaction relationship: participates_in CCO:I0016713 ! map3k3-gnb1 physical interaction relationship: participates_in CCO:I0016714 ! map3k3-fasn physical interaction relationship: participates_in CCO:I0016715 ! map3k3-cct3 physical interaction relationship: participates_in CCO:I0016716 ! map3k3-xpot physical interaction relationship: participates_in CCO:I0016717 ! map3k3-plod physical interaction relationship: participates_in CCO:I0016718 ! map3k3-cct6a physical interaction relationship: participates_in CCO:I0016719 ! map3k3-mm_1 physical interaction relationship: participates_in CCO:I0016720 ! map3k3-st13 physical interaction relationship: participates_in CCO:I0016721 ! map3k3-hsp70_1 physical interaction relationship: participates_in CCO:I0016722 ! map3k3-q9buf5 physical interaction relationship: participates_in CCO:I0016723 ! map3k3-hspa8 physical interaction relationship: participates_in CCO:I0016724 ! map3k3-myo6 physical interaction relationship: participates_in CCO:I0016725 ! map3k3-uba52-1 physical interaction relationship: participates_in CCO:I0016726 ! map3k3-q969i2 physical interaction relationship: participates_in CCO:I0016727 ! map3k3-s100a8 physical interaction relationship: participates_in CCO:I0016728 ! map3k3-q9nws0 physical interaction relationship: participates_in CCO:I0016729 ! map3k3-q9bv68 physical interaction relationship: participates_in CCO:I0016730 ! map3k3-q96lm8 physical interaction relationship: participates_in CCO:I0016731 ! map3k3-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016732 ! map3k3-q8n532 physical interaction relationship: participates_in CCO:I0016733 ! map3k3-kiaa0147 physical interaction relationship: participates_in CCO:I0016734 ! map3k3-uxt physical interaction relationship: participates_in CCO:I0016735 ! map3k3-q9bzf9 physical interaction relationship: participates_in CCO:I0016736 ! map3k3-alk physical interaction relationship: participates_in CCO:I0016737 ! map3k3-dnaja3 physical interaction relationship: participates_in CCO:I0016738 ! map3k3-map3k2 physical interaction relationship: participates_in CCO:I0016739 ! map3k3-flna physical interaction relationship: participates_in CCO:I0016740 ! map3k3-map3k3 physical interaction relationship: participates_in CCO:I0016741 ! map3k3-ppp1r12a physical interaction relationship: participates_in CCO:I0016742 ! map3k3-myh9 physical interaction relationship: participates_in CCO:I0016743 ! map3k3-lyn physical interaction relationship: participates_in CCO:I0016744 ! map3k3-q8taq2 physical interaction relationship: participates_in CCO:I0016745 ! map3k3-vbp1 physical interaction relationship: participates_in CCO:I0016746 ! map3k3-vim physical interaction relationship: participates_in CCO:I0016747 ! map3k3-h4f2 physical interaction relationship: participates_in CCO:I0016748 ! map3k3-sptbn1 physical interaction relationship: participates_in CCO:I0016749 ! map3k3-slc25a6 physical interaction relationship: participates_in CCO:I0016750 ! map3k3-q8n8k8 physical interaction relationship: participates_in CCO:I0016751 ! map3k3-q8izp2 physical interaction relationship: participates_in CCO:I0016752 ! map3k3-pygm physical interaction relationship: participates_in CCO:I0016753 ! map3k3-tuba2 physical interaction relationship: participates_in CCO:I0016754 ! map3k3-dkfzp434k0435 physical interaction relationship: participates_in CCO:I0016755 ! map3k3-prkdc physical interaction relationship: participates_in CCO:I0016756 ! map3k3-myl6 physical interaction relationship: participates_in CCO:I0016757 ! map3k3-gapd physical interaction relationship: participates_in CCO:I0016758 ! map3k3-lgals7 physical interaction relationship: participates_in CCO:I0016759 ! map3k3-kiaa0310 physical interaction relationship: participates_in CCO:I0016760 ! map3k3-s100a7 physical interaction relationship: participates_in CCO:I0016761 ! map3k3-cfl2 physical interaction relationship: participates_in CCO:I0016762 ! map3k3-nakap95 physical interaction relationship: participates_in CCO:I0016763 ! map3k3-cpvl physical interaction relationship: participates_in CCO:I0016764 ! map3k3-dnajc7 physical interaction relationship: participates_in CCO:I0016765 ! map3k3-myo1a physical interaction relationship: participates_in CCO:I0016766 ! map3k3-mlcb physical interaction relationship: participates_in CCO:I0016767 ! map3k3-gnai3 physical interaction relationship: participates_in CCO:I0016768 ! map3k3-iqgap2 physical interaction relationship: participates_in CCO:I0016769 ! map3k3-rps16 physical interaction relationship: participates_in CCO:I0016770 ! map3k3-rps27 physical interaction relationship: participates_in CCO:I0016771 ! map3k3-mylk2 physical interaction relationship: participates_in CCO:I0016772 ! map3k3-myo1d physical interaction relationship: participates_in CCO:I0016773 ! map3k3-tuba1 physical interaction relationship: participates_in CCO:I0017231 ! map3k3-ywhaz physical interaction relationship: participates_in CCO:I0017232 ! map3k3-ywhab physical interaction relationship: participates_in CCO:I0017233 ! map3k3-ywhae physical interaction relationship: participates_in CCO:I0017234 ! map3k3-ywhah physical interaction relationship: participates_in CCO:I0017235 ! map3k3-ywhag physical interaction relationship: participates_in CCO:I0017236 ! map3k3-c20orf126 physical interaction relationship: participates_in CCO:I0017237 ! map3k3-hspa9b physical interaction relationship: participates_in CCO:I0017238 ! map3k3-hspca physical interaction relationship: participates_in CCO:I0017239 ! map3k3-hspcb physical interaction relationship: participates_in CCO:I0017240 ! map3k3-map2k5 physical interaction relationship: participates_in CCO:I0017241 ! map3k3-pfdn2 physical interaction relationship: participates_in CCO:I0019232 ! traf7-map3k3-1 physical interaction relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0012733 ! M3K3_HUMAN-Phosphotyrosine288 relationship: transforms_into CCO:B0012734 ! M3K3_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0012735 ! M3K3_HUMAN-Phosphothreonine294 relationship: transforms_into CCO:B0012736 ! M3K3_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0012737 ! M3K3_HUMAN-Phosphoserine340 relationship: transforms_into CCO:B0012738 ! M3K3_HUMAN-Phosphothreonine530 relationship: transforms_into CCO:B0048313 ! M3K3_HUMAN-Phosphoserine166 [Term] id: CCO:B0005527 name: NFKB2_HUMAN def: "Nuclear factor NF-kappa-B p100 subunit" [UniProtKB:Q00653] synonym: "DNA-binding factor KBF2" EXACT [UniProtKB:Q00653] synonym: "H2TF1" EXACT [UniProtKB:Q00653] synonym: "Lymphocyte translocation chromosome 10" EXACT [UniProtKB:Q00653] synonym: "Lyt10" EXACT [UniProtKB:Q00653] synonym: "Oncogene Lyt-10" EXACT [UniProtKB:Q00653] xref: EMBL:AAA21462.2 xref: EMBL:AAA68171.1 xref: EMBL:AAB21124.1 xref: EMBL:AAH02844.1 xref: EMBL:AAP88771.1 xref: EMBL:AAW56071.1 xref: EMBL:CAA43715.1 xref: EMBL:CAA43716.1 xref: EMBL:CAC08399.1 xref: UniProtKB:Q00653 xref: UniProtKB:Q04860 xref: UniProtKB:Q9BU75 xref: UniProtKB:Q9H471 xref: UniProtKB:Q9H472 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005187 ! NFKB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006388 ! nfkb2-rps4x physical interaction relationship: participates_in CCO:I0008964 ! nfkb2-rps15a physical interaction relationship: participates_in CCO:I0016345 ! map3k8-nfkb2 physical interaction relationship: participates_in CCO:I0016364 ! rel-nfkb2 physical interaction relationship: participates_in CCO:I0016383 ! nfkbia-nfkb2 physical interaction relationship: participates_in CCO:I0016408 ! nfkbib-nfkb2 physical interaction relationship: participates_in CCO:I0016427 ! nfkbie-nfkb2 physical interaction relationship: participates_in CCO:I0016774 ! nfkb2-pdcd8 physical interaction relationship: participates_in CCO:I0016775 ! nfkb2-hspa1l-1 physical interaction relationship: participates_in CCO:I0016776 ! nfkb2-hspa5-1 physical interaction relationship: participates_in CCO:I0016777 ! nfkb2-snrp116 physical interaction relationship: participates_in CCO:I0016778 ! nfkb2-hspa8-1 physical interaction relationship: participates_in CCO:I0016779 ! nfkb2-rars physical interaction relationship: participates_in CCO:I0016780 ! nfkb2-q12905 physical interaction relationship: participates_in CCO:I0016781 ! nfkb2-hspa9b-1 physical interaction relationship: participates_in CCO:I0016782 ! nfkb2-mars physical interaction relationship: participates_in CCO:I0016783 ! nfkb2-rps5 physical interaction relationship: participates_in CCO:I0016784 ! nfkb2-rps10 physical interaction relationship: participates_in CCO:I0016785 ! nfkb2-rplp2 physical interaction relationship: participates_in CCO:I0016786 ! nfkb2-iqgap1 physical interaction relationship: participates_in CCO:I0016787 ! nfkb2-nfkbie physical interaction relationship: participates_in CCO:I0016788 ! nfkb2-rps3 physical interaction relationship: participates_in CCO:I0016789 ! nfkb2-polrmt physical interaction relationship: participates_in CCO:I0016790 ! nfkb2-dnaja1 physical interaction relationship: participates_in CCO:I0016791 ! nfkb2-iars-1 physical interaction relationship: participates_in CCO:I0016792 ! nfkb2-rps18 physical interaction relationship: participates_in CCO:I0016793 ! nfkb2-eprs physical interaction relationship: participates_in CCO:I0016794 ! nfkb2-pabpc1 physical interaction relationship: participates_in CCO:I0016795 ! nfkb2-eef1a2-1 physical interaction relationship: participates_in CCO:I0016796 ! nfkb2-ddx21 physical interaction relationship: participates_in CCO:I0016797 ! nfkb2-matr3 physical interaction relationship: participates_in CCO:I0016798 ! nfkb2-dap3 physical interaction relationship: participates_in CCO:I0016799 ! nfkb2-cad-1 physical interaction relationship: participates_in CCO:I0016800 ! nfkb2-hadhb physical interaction relationship: participates_in CCO:I0016801 ! nfkb2-cltc-1 physical interaction relationship: participates_in CCO:I0016802 ! nfkb2-ikbkb physical interaction relationship: participates_in CCO:I0016803 ! nfkb2-rps11 physical interaction relationship: participates_in CCO:I0016804 ! nfkb2-rps14 physical interaction relationship: participates_in CCO:I0016805 ! nfkb2-fasn physical interaction relationship: participates_in CCO:I0016806 ! nfkb2-gemin4 physical interaction relationship: participates_in CCO:I0016807 ! nfkb2-rpl7 physical interaction relationship: participates_in CCO:I0016808 ! nfkb2-hadha physical interaction relationship: participates_in CCO:I0016809 ! nfkb2-hsp70_1-1 physical interaction relationship: participates_in CCO:I0016810 ! nfkb2-q9buf5 physical interaction relationship: participates_in CCO:I0016811 ! nfkb2-lkp physical interaction relationship: participates_in CCO:I0016812 ! nfkb2-a_951c1a1 physical interaction relationship: participates_in CCO:I0016813 ! nfkb2-nfkb2-1 physical interaction relationship: participates_in CCO:I0016814 ! nfkb2-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016815 ! nfkb2-q8nhw5 physical interaction relationship: participates_in CCO:I0016816 ! nfkb2-dnaja3 physical interaction relationship: participates_in CCO:I0016817 ! nfkb2-hnrpu physical interaction relationship: participates_in CCO:I0016818 ! nfkb2-dhx9 physical interaction relationship: participates_in CCO:I0016819 ! nfkb2-rpl18 physical interaction relationship: participates_in CCO:I0016820 ! nfkb2-rps19 physical interaction relationship: participates_in CCO:I0016821 ! nfkb2-rps8 physical interaction relationship: participates_in CCO:I0016822 ! nfkb2-hnrpc physical interaction relationship: participates_in CCO:I0016823 ! nfkb2-sfpq physical interaction relationship: participates_in CCO:I0016824 ! nfkb2-adprt physical interaction relationship: participates_in CCO:I0016825 ! nfkb2-hspca-1 physical interaction relationship: participates_in CCO:I0016826 ! nfkb2-ncl physical interaction relationship: participates_in CCO:I0016827 ! nfkb2-prkdc physical interaction relationship: participates_in CCO:I0016828 ! nfkb2-tuba2-1 physical interaction relationship: participates_in CCO:I0016829 ! nfkb2-rpl7a physical interaction relationship: participates_in CCO:I0016830 ! nfkb2-rps3a physical interaction relationship: participates_in CCO:I0016831 ! nfkb2-rpl13 physical interaction relationship: participates_in CCO:I0016832 ! nfkb2-rps24 physical interaction relationship: participates_in CCO:I0016833 ! nfkb2-hist1h2bb physical interaction relationship: participates_in CCO:I0016834 ! nfkb2-xrcc5 physical interaction relationship: participates_in CCO:I0016835 ! nfkb2-usp9x physical interaction relationship: participates_in CCO:I0016836 ! nfkb2-rps16 physical interaction relationship: participates_in CCO:I0016837 ! nfkb2-rps27 physical interaction relationship: participates_in CCO:I0016838 ! nfkb2-tuba1 physical interaction relationship: participates_in CCO:I0016878 ! relb-nfkb2 physical interaction relationship: participates_in CCO:I0017187 ! nfkb2-flip1 physical interaction relationship: participates_in CCO:I0017188 ! nfkb2-map3k8 physical interaction relationship: participates_in CCO:I0017189 ! nfkb2-rel-1 physical interaction relationship: participates_in CCO:I0017190 ! nfkb2-ddx3x physical interaction relationship: participates_in CCO:I0017191 ! nfkb2-glg1 physical interaction relationship: participates_in CCO:I0017192 ! nfkb2-gtf2i physical interaction relationship: participates_in CCO:I0017193 ! nfkb2-nfkbia-1 physical interaction relationship: participates_in CCO:I0017194 ! nfkb2-nfkbib-1 physical interaction relationship: participates_in CCO:I0017195 ! nfkb2-chuk-1 physical interaction relationship: participates_in CCO:I0017196 ! nfkb2-ikbkg-2 physical interaction relationship: participates_in CCO:I0017197 ! nfkb2-nfkb1-1 physical interaction relationship: participates_in CCO:I0017198 ! nfkb2-relb-1 physical interaction relationship: participates_in CCO:I0017199 ! nfkb2-rpl6 physical interaction relationship: participates_in CCO:I0017200 ! nfkb2-rps13 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013164 ! NFKB2_HUMAN-Phosphoserine713 relationship: transforms_into CCO:B0013165 ! NFKB2_HUMAN-Phosphoserine715 relationship: transforms_into CCO:B0013166 ! NFKB2_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0013167 ! NFKB2_HUMAN-Phosphoserine866 relationship: transforms_into CCO:B0013168 ! NFKB2_HUMAN-Phosphoserine870 relationship: transforms_into CCO:B0068670 ! NFKB2_HUMAN-Phosphothreonine429 [Term] id: CCO:B0005528 name: M3K14_HUMAN def: "Mitogen-activated protein kinase kinase kinase 14" [UniProtKB:Q99558] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q99558] synonym: "HsNIK" EXACT [UniProtKB:Q99558] synonym: "NF-kappa beta-inducing kinase" EXACT [UniProtKB:Q99558] synonym: "Serine/threonine-protein kinase NIK" EXACT [UniProtKB:Q99558] xref: EMBL:AAH35576.1 xref: EMBL:ABC40733.1 xref: EMBL:CAA71306.1 xref: UniProtKB:Q8IYN1 xref: UniProtKB:Q99558 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005005 ! MAP3K14_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006389 ! map3k14-ruvbl1 physical interaction relationship: participates_in CCO:I0006390 ! map3k14-q9bva1 physical interaction relationship: participates_in CCO:I0006391 ! map3k14-rps4x physical interaction relationship: participates_in CCO:I0006392 ! map3k14-rara physical interaction relationship: participates_in CCO:I0006427 ! map3k14-cdc37 physical interaction relationship: participates_in CCO:I0008965 ! map3k14-rps15a physical interaction relationship: participates_in CCO:I0015933 ! edar-nik physical interaction relationship: participates_in CCO:I0016117 ! ikk-nik physical interaction relationship: participates_in CCO:I0016839 ! map3k14-q12905 physical interaction relationship: participates_in CCO:I0016840 ! map3k14-hspa9b physical interaction relationship: participates_in CCO:I0016841 ! map3k14-ruvbl2 physical interaction relationship: participates_in CCO:I0016842 ! map3k14-traf3 physical interaction relationship: participates_in CCO:I0016843 ! map3k14-pabpc1 physical interaction relationship: participates_in CCO:I0016844 ! map3k14-atp5a1 physical interaction relationship: participates_in CCO:I0016845 ! map3k14-glud1 physical interaction relationship: participates_in CCO:I0016846 ! map3k14-nsep1 physical interaction relationship: participates_in CCO:I0016847 ! map3k14-rap1b physical interaction relationship: participates_in CCO:I0016848 ! map3k14-sfpq physical interaction relationship: participates_in CCO:I0016849 ! map3k14-csda physical interaction relationship: participates_in CCO:I0016850 ! map3k14-rps3a physical interaction relationship: participates_in CCO:I0017201 ! map3k14-hspca physical interaction relationship: participates_in CCO:I0017242 ! map3k14-hspcb physical interaction relationship: participates_in CCO:I0017243 ! map3k14-chuk physical interaction relationship: participates_in CCO:I0017244 ! map3k14-ikbkb physical interaction relationship: participates_in CCO:I0017245 ! map3k14-ikbkg physical interaction relationship: participates_in CCO:I0017246 ! map3k14-rpl6 physical interaction relationship: participates_in CCO:I0018621 ! chuk-map3k14-2 phosphorylation relationship: participates_in CCO:I0018631 ! chuk-map3k14-1 phosphorylation relationship: participates_in CCO:I0018685 ! traf6-map3k14-1 physical interaction relationship: participates_in CCO:I0018686 ! traf6-map3k14-2 physical interaction [Term] id: CCO:B0005529 name: RELB_HUMAN def: "Transcription factor RelB" [UniProtKB:Q01201] synonym: "I-Rel" EXACT [UniProtKB:Q01201] xref: EMBL:AAA36127.1 xref: EMBL:AAC82346.1 xref: EMBL:AAH28013.1 xref: EMBL:ABC40746.1 xref: UniProtKB:Q01201 xref: UniProtKB:Q6GTX7 xref: UniProtKB:Q9UEI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005464 ! RELB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006393 ! relb-ruvbl1 physical interaction relationship: participates_in CCO:I0006437 ! relb-hdac6 physical interaction relationship: participates_in CCO:I0006438 ! relb-kpna2 physical interaction relationship: participates_in CCO:I0016851 ! relb-kpnb1 physical interaction relationship: participates_in CCO:I0016852 ! relb-kpna1 physical interaction relationship: participates_in CCO:I0016853 ! relb-hspa1l physical interaction relationship: participates_in CCO:I0016854 ! relb-hspa5 physical interaction relationship: participates_in CCO:I0016855 ! relb-hspa8 physical interaction relationship: participates_in CCO:I0016856 ! relb-usp7 physical interaction relationship: participates_in CCO:I0016857 ! relb-chuk physical interaction relationship: participates_in CCO:I0016858 ! relb-hspa9b physical interaction relationship: participates_in CCO:I0016859 ! relb-rps5 physical interaction relationship: participates_in CCO:I0016860 ! relb-rps10 physical interaction relationship: participates_in CCO:I0016861 ! relb-rplp2 physical interaction relationship: participates_in CCO:I0016862 ! relb-nfkbie physical interaction relationship: participates_in CCO:I0016863 ! relb-hspa6 physical interaction relationship: participates_in CCO:I0016864 ! relb-o43809 physical interaction relationship: participates_in CCO:I0016865 ! relb-eprs physical interaction relationship: participates_in CCO:I0016866 ! relb-c1qbp physical interaction relationship: participates_in CCO:I0016867 ! relb-nfkbia physical interaction relationship: participates_in CCO:I0016868 ! relb-hsd17b4 physical interaction relationship: participates_in CCO:I0016869 ! relb-cad physical interaction relationship: participates_in CCO:I0016870 ! relb-actg1 physical interaction relationship: participates_in CCO:I0016871 ! relb-cltc physical interaction relationship: participates_in CCO:I0016872 ! relb-rps11 physical interaction relationship: participates_in CCO:I0016873 ! relb-rps14 physical interaction relationship: participates_in CCO:I0016874 ! relb-hpbrii_4 physical interaction relationship: participates_in CCO:I0016875 ! relb-hsp70_1 physical interaction relationship: participates_in CCO:I0016876 ! relb-nono physical interaction relationship: participates_in CCO:I0016877 ! relb-baf60b physical interaction relationship: participates_in CCO:I0016878 ! relb-nfkb2 physical interaction relationship: participates_in CCO:I0016879 ! relb-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016880 ! relb-q8nhw5 physical interaction relationship: participates_in CCO:I0016881 ! relb-q96ta9 physical interaction relationship: participates_in CCO:I0016882 ! relb-hnrpu physical interaction relationship: participates_in CCO:I0016883 ! relb-sfpq physical interaction relationship: participates_in CCO:I0016884 ! relb-dsp physical interaction relationship: participates_in CCO:I0016885 ! relb-prkdc physical interaction relationship: participates_in CCO:I0016886 ! relb-tuba2 physical interaction relationship: participates_in CCO:I0016887 ! relb-nqo2 physical interaction relationship: participates_in CCO:I0016888 ! relb-ddx1 physical interaction relationship: participates_in CCO:I0016889 ! relb-usp9x physical interaction relationship: participates_in CCO:I0016890 ! relb-relb physical interaction relationship: participates_in CCO:I0016891 ! relb-smarcd1 physical interaction relationship: participates_in CCO:I0017198 ! nfkb2-relb-1 physical interaction relationship: participates_in CCO:I0017247 ! relb-kpna6 physical interaction relationship: participates_in CCO:I0017248 ! relb-nfkb1 physical interaction relationship: participates_in CCO:I0017249 ! relb-dpf2 physical interaction relationship: participates_in CCO:I0017250 ! relb-smarca4 physical interaction relationship: participates_in CCO:I0017251 ! relb-baf155 physical interaction relationship: participates_in CCO:I0017252 ! relb-q8taq2 physical interaction relationship: participates_in CCO:I0017253 ! relb-q9h836 physical interaction relationship: participates_in CCO:I0017254 ! relb-usp11 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0041178 ! RELB_HUMAN-Phosphothreonine103 relationship: transforms_into CCO:B0041179 ! RELB_HUMAN-Phosphoserine573 relationship: transforms_into CCO:B0069856 ! RELB_HUMAN-Phosphoserine37 [Term] id: CCO:B0005531 name: TAB1_HUMAN def: "Mitogen-activated protein kinase kinase kinase 7-interacting protein 1" [UniProtKB:Q15750] synonym: "TAK1-binding protein 1" EXACT [UniProtKB:Q15750] synonym: "TGF-beta-activated kinase 1-binding protein 1" EXACT [UniProtKB:Q15750] xref: EMBL:AAC12660.1 xref: EMBL:AAH50554.1 xref: EMBL:ABC40735.1 xref: EMBL:CAB55304.1 xref: UniProtKB:Q15750 xref: UniProtKB:Q2PP09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005719 ! MAP3K7IP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006405 ! map3k7ip1-ruvbl1 physical interaction relationship: participates_in CCO:I0006406 ! map3k7ip1-q9bva1 physical interaction relationship: participates_in CCO:I0016116 ! traf6-tab1-1 physical interaction relationship: participates_in CCO:I0016921 ! map3k7ip1-hspa1l physical interaction relationship: participates_in CCO:I0016922 ! map3k7ip1-hspa4 physical interaction relationship: participates_in CCO:I0016923 ! map3k7ip1-hspa5 physical interaction relationship: participates_in CCO:I0016924 ! map3k7ip1-hspa8 physical interaction relationship: participates_in CCO:I0016925 ! map3k7ip1-hspa9b physical interaction relationship: participates_in CCO:I0016926 ! map3k7ip1-hspa6 physical interaction relationship: participates_in CCO:I0016927 ! map3k7ip1-dnaja1 physical interaction relationship: participates_in CCO:I0016928 ! map3k7ip1-map3k7ip1 physical interaction relationship: participates_in CCO:I0016929 ! map3k7ip1-osp94 physical interaction relationship: participates_in CCO:I0016930 ! map3k7ip1-hsp70_1 physical interaction relationship: participates_in CCO:I0016931 ! map3k7ip1-irak1 physical interaction relationship: participates_in CCO:I0016932 ! map3k7ip1-hspca physical interaction relationship: participates_in CCO:I0016933 ! map3k7ip1-tuba2 physical interaction relationship: participates_in CCO:I0016934 ! map3k7ip1-dnajc7 physical interaction relationship: participates_in CCO:I0017255 ! map3k7ip1-traf2 physical interaction relationship: participates_in CCO:I0017256 ! q9nyj8-map3k7ip1 physical interaction relationship: participates_in CCO:I0017501 ! traf6-tab1 physical interaction relationship: participates_in CCO:P0000409 ! activation of MAPKKK activity relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: transforms_into CCO:B0048404 ! TAB1_HUMAN-Phosphoserine7 [Term] id: CCO:B0005532 name: TAB2_HUMAN def: "Mitogen-activated protein kinase kinase kinase 7-interacting protein 2" [UniProtKB:Q9NYJ8] synonym: "TAK1-binding protein 2" EXACT [UniProtKB:Q9NYJ8] xref: EMBL:AAF67176.1 xref: EMBL:AAH35910.1 xref: EMBL:ABC40736.1 xref: EMBL:BAA34453.2 xref: EMBL:CAB55907.1 xref: EMBL:CAG33668.1 xref: EMBL:CAI19581.1 xref: EMBL:CAI20026.1 xref: EMBL:CAI20971.1 xref: UniProtKB:O94838 xref: UniProtKB:Q6I9W8 xref: UniProtKB:Q76N06 xref: UniProtKB:Q9NYJ8 xref: UniProtKB:Q9UFP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005720 ! MAP3K7IP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006407 ! q9nyj8-hspa2 physical interaction relationship: participates_in CCO:I0006408 ! q9nyj8-ruvbl1 physical interaction relationship: participates_in CCO:I0016935 ! q9nyj8-bag2 physical interaction relationship: participates_in CCO:I0016936 ! q9nyj8-ywhae physical interaction relationship: participates_in CCO:I0016937 ! q9nyj8-hspa5 physical interaction relationship: participates_in CCO:I0016938 ! q9nyj8-hspa8 physical interaction relationship: participates_in CCO:I0016939 ! q9nyj8-hspa9b physical interaction relationship: participates_in CCO:I0016940 ! q9nyj8-ruvbl2 physical interaction relationship: participates_in CCO:I0016941 ! q9nyj8-rpl23 physical interaction relationship: participates_in CCO:I0016942 ! q9nyj8-dnaja1 physical interaction relationship: participates_in CCO:I0016943 ! q9nyj8-hnrph1 physical interaction relationship: participates_in CCO:I0016944 ! q9nyj8-c1qbp physical interaction relationship: participates_in CCO:I0016945 ! q9nyj8-eef1a2 physical interaction relationship: participates_in CCO:I0016946 ! q9nyj8-sptan1 physical interaction relationship: participates_in CCO:I0016947 ! q9nyj8-cad physical interaction relationship: participates_in CCO:I0016948 ! q9nyj8-actg1 physical interaction relationship: participates_in CCO:I0016949 ! q9nyj8-lgals3bp physical interaction relationship: participates_in CCO:I0016950 ! q9nyj8-cltc physical interaction relationship: participates_in CCO:I0016951 ! q9nyj8-sec13l1 physical interaction relationship: participates_in CCO:I0016952 ! q9nyj8-hsp70_1 physical interaction relationship: participates_in CCO:I0016953 ! q9nyj8-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016954 ! q9nyj8-flna physical interaction relationship: participates_in CCO:I0016955 ! q9nyj8-hspca physical interaction relationship: participates_in CCO:I0016956 ! q9nyj8-tuba2 physical interaction relationship: participates_in CCO:I0016957 ! q9nyj8-rps27 physical interaction relationship: participates_in CCO:I0017256 ! q9nyj8-map3k7ip1 physical interaction relationship: participates_in CCO:I0017501 ! traf6-tab1 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0014292 ! TAB2_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0071075 ! TAB2_HUMAN-Phosphoserine372 [Term] id: CCO:B0005533 name: TBK1_HUMAN def: "Serine/threonine-protein kinase TBK1" [UniProtKB:Q9UHD2] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UHD2] synonym: "NF-kappa-B-activating kinase" EXACT [UniProtKB:Q9UHD2] synonym: "T2K" EXACT [UniProtKB:Q9UHD2] synonym: "TANK-binding kinase 1" EXACT [UniProtKB:Q9UHD2] xref: EMBL:AAF05989.1 xref: EMBL:AAF69106.1 xref: EMBL:AAH34950.1 xref: EMBL:BAA92129.1 xref: UniProtKB:Q8IYV3 xref: UniProtKB:Q9NUJ5 xref: UniProtKB:Q9UHD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005741 ! TBK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006409 ! tbk1-cct7 physical interaction relationship: participates_in CCO:I0006410 ! tbk1-ruvbl1 physical interaction relationship: participates_in CCO:I0006411 ! tbk1-cct2 physical interaction relationship: participates_in CCO:I0006412 ! tbk1-cct4 physical interaction relationship: participates_in CCO:I0006439 ! tbk1-cdc37 physical interaction relationship: participates_in CCO:I0015989 ! tbk1-birc4 phosphorylation relationship: participates_in CCO:I0016583 ! tank-tbk1 physical interaction relationship: participates_in CCO:I0016958 ! tbk1-cct8 physical interaction relationship: participates_in CCO:I0016959 ! tbk1-hspa5 physical interaction relationship: participates_in CCO:I0016960 ! tbk1-hspa8 physical interaction relationship: participates_in CCO:I0016961 ! tbk1-hspa9b physical interaction relationship: participates_in CCO:I0016962 ! tbk1-rps5 physical interaction relationship: participates_in CCO:I0016963 ! tbk1-ruvbl2 physical interaction relationship: participates_in CCO:I0016964 ! tbk1-cct5 physical interaction relationship: participates_in CCO:I0016965 ! tbk1-rps18 physical interaction relationship: participates_in CCO:I0016966 ! tbk1-atp5a1 physical interaction relationship: participates_in CCO:I0016967 ! tbk1-cct1 physical interaction relationship: participates_in CCO:I0016968 ! tbk1-lgals3bp physical interaction relationship: participates_in CCO:I0016969 ! tbk1-cct3 physical interaction relationship: participates_in CCO:I0016970 ! tbk1-cct6a physical interaction relationship: participates_in CCO:I0016971 ! tbk1-rpl7 physical interaction relationship: participates_in CCO:I0016972 ! tbk1-hsp70_1 physical interaction relationship: participates_in CCO:I0016973 ! tbk1-nono physical interaction relationship: participates_in CCO:I0016974 ! tbk1-q8nhw5 physical interaction relationship: participates_in CCO:I0016975 ! tbk1-rps8 physical interaction relationship: participates_in CCO:I0016976 ! tbk1-sfpq physical interaction relationship: participates_in CCO:I0016977 ! tbk1-tbk1 physical interaction relationship: participates_in CCO:I0016978 ! tbk1-gapd physical interaction relationship: participates_in CCO:I0016979 ! tbk1-tuba2 physical interaction relationship: participates_in CCO:I0016980 ! tbk1-rpl13 physical interaction relationship: participates_in CCO:I0016981 ! tbk1-ldhb physical interaction relationship: participates_in CCO:I0017222 ! ikbkg-tbk1 physical interaction relationship: participates_in CCO:I0017257 ! tbk1-hspca physical interaction relationship: participates_in CCO:I0017258 ! tbk1-hspcb physical interaction relationship: participates_in CCO:I0017259 ! tbk1-tank-1 physical interaction relationship: participates_in CCO:I0017260 ! tbk1-tilp physical interaction relationship: participates_in CCO:I0017261 ! tbk1-traf2 physical interaction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0014318 ! TBK1_HUMAN-Phosphoserine172 [Term] id: CCO:B0005534 name: TNR1A_HUMAN def: "Tumor necrosis factor receptor superfamily member 1A precursor" [UniProtKB:P19438] synonym: "CD120a antigen" EXACT [UniProtKB:P19438] synonym: "p55" EXACT [UniProtKB:P19438] synonym: "p60" EXACT [UniProtKB:P19438] synonym: "TNF-R1" EXACT [UniProtKB:P19438] synonym: "TNF-RI" EXACT [UniProtKB:P19438] synonym: "TNFR-I" EXACT [UniProtKB:P19438] xref: EMBL:AAA03210.1 xref: EMBL:AAA36753.1 xref: EMBL:AAA36754.1 xref: EMBL:AAA36756.1 xref: EMBL:AAA61201.1 xref: EMBL:AAH10140.1 xref: EMBL:AAM77802.1 xref: EMBL:CAA01558.1 xref: EMBL:CAA39021.1 xref: UniProtKB:P19438 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005803 ! TNFRSF1A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001358 ! tumor necrosis factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006413 ! tnfrsf1a-ruvbl1 physical interaction relationship: participates_in CCO:I0006414 ! tnfrsf1a-q9bva1 physical interaction relationship: participates_in CCO:I0006440 ! tnfrsf1a-fancd2 physical interaction relationship: participates_in CCO:I0006441 ! tnfrsf1a-tnf physical interaction relationship: participates_in CCO:I0006858 ! tnf-tnfrsf1a-2 physical interaction relationship: participates_in CCO:I0006859 ! tnf-tnfrsf1a-3 physical interaction relationship: participates_in CCO:I0006860 ! tnf-tnfrsf1a-4 physical interaction relationship: participates_in CCO:I0007246 ! tnf-tnfrsf1a-1 direct interaction relationship: participates_in CCO:I0008550 ! tnfrsf1a-myh10 physical interaction relationship: participates_in CCO:I0016982 ! tnfrsf1a-bag2 physical interaction relationship: participates_in CCO:I0016983 ! tnfrsf1a-afg3l2 physical interaction relationship: participates_in CCO:I0016984 ! tnfrsf1a-sel1l physical interaction relationship: participates_in CCO:I0016985 ! tnfrsf1a-hspa1l physical interaction relationship: participates_in CCO:I0016986 ! tnfrsf1a-hspa5 physical interaction relationship: participates_in CCO:I0016987 ! tnfrsf1a-hspa8 physical interaction relationship: participates_in CCO:I0016988 ! tnfrsf1a-rars physical interaction relationship: participates_in CCO:I0016989 ! tnfrsf1a-atp1a1 physical interaction relationship: participates_in CCO:I0016990 ! tnfrsf1a-slc25a5 physical interaction relationship: participates_in CCO:I0016991 ! tnfrsf1a-ipo8 physical interaction relationship: participates_in CCO:I0016992 ! tnfrsf1a-hspa9b physical interaction relationship: participates_in CCO:I0016993 ! tnfrsf1a-rpl23 physical interaction relationship: participates_in CCO:I0016994 ! tnfrsf1a-hs1bp1 physical interaction relationship: participates_in CCO:I0016995 ! tnfrsf1a-eppk1 physical interaction relationship: participates_in CCO:I0016996 ! tnfrsf1a-rps3 physical interaction relationship: participates_in CCO:I0016997 ! tnfrsf1a-hspa6 physical interaction relationship: participates_in CCO:I0016998 ! tnfrsf1a-dnaja1 physical interaction relationship: participates_in CCO:I0016999 ! tnfrsf1a-c1qbp physical interaction relationship: participates_in CCO:I0017000 ! tnfrsf1a-dnajb12 physical interaction relationship: participates_in CCO:I0017001 ! tnfrsf1a-atp5a1 physical interaction relationship: participates_in CCO:I0017002 ! tnfrsf1a-tnfrsf1a physical interaction relationship: participates_in CCO:I0017003 ! tnfrsf1a-ssr4 physical interaction relationship: participates_in CCO:I0017004 ! tnfrsf1a-slc1a5 physical interaction relationship: participates_in CCO:I0017005 ! tnfrsf1a-cad physical interaction relationship: participates_in CCO:I0017006 ! tnfrsf1a-canx physical interaction relationship: participates_in CCO:I0017007 ! tnfrsf1a-actg1 physical interaction relationship: participates_in CCO:I0017008 ! tnfrsf1a-slc25a3 physical interaction relationship: participates_in CCO:I0017009 ! tnfrsf1a-cltcl1 physical interaction relationship: participates_in CCO:I0017010 ! tnfrsf1a-cdipt physical interaction relationship: participates_in CCO:I0017011 ! tnfrsf1a-nap1l1 physical interaction relationship: participates_in CCO:I0017012 ! tnfrsf1a-cltc physical interaction relationship: participates_in CCO:I0017013 ! tnfrsf1a-ddost physical interaction relationship: participates_in CCO:I0017014 ! tnfrsf1a-xpot physical interaction relationship: participates_in CCO:I0017015 ! tnfrsf1a-rcn2 physical interaction relationship: participates_in CCO:I0017016 ! tnfrsf1a-hadha physical interaction relationship: participates_in CCO:I0017017 ! tnfrsf1a-hsp70_1 physical interaction relationship: participates_in CCO:I0017018 ! tnfrsf1a-q9buf5 physical interaction relationship: participates_in CCO:I0017019 ! tnfrsf1a-myo6 physical interaction relationship: participates_in CCO:I0017020 ! tnfrsf1a-uba52 physical interaction relationship: participates_in CCO:I0017021 ! tnfrsf1a-q96ag4 physical interaction relationship: participates_in CCO:I0017022 ! tnfrsf1a-rps27 physical interaction relationship: participates_in CCO:I0017023 ! tnfrsf1a-dnaja3 physical interaction relationship: participates_in CCO:I0017024 ! tnfrsf1a-kiaa0219 physical interaction relationship: participates_in CCO:I0017025 ! tnfrsf1a-myh9 physical interaction relationship: participates_in CCO:I0017026 ! tnfrsf1a-hist3h3 physical interaction relationship: participates_in CCO:I0017027 ! tnfrsf1a-h4f2 physical interaction relationship: participates_in CCO:I0017028 ! tnfrsf1a-slc25a6 physical interaction relationship: participates_in CCO:I0017029 ! tnfrsf1a-sec61a1 physical interaction relationship: participates_in CCO:I0017030 ! tnfrsf1a-prkdc physical interaction relationship: participates_in CCO:I0017031 ! tnfrsf1a-myl6 physical interaction relationship: participates_in CCO:I0017032 ! tnfrsf1a-tuba2 physical interaction relationship: participates_in CCO:I0017033 ! tnfrsf1a-atp2a2 physical interaction relationship: participates_in CCO:I0017034 ! tnfrsf1a-hist1h2bb physical interaction relationship: participates_in CCO:I0017035 ! tnfrsf1a-mlcb physical interaction relationship: participates_in CCO:I0017036 ! tnfrsf1a-rps16 physical interaction relationship: participates_in CCO:I0018014 ! tnfrsf1a-tnfrsf1a-1 physical interaction relationship: participates_in CCO:I0018015 ! tnfrsf1a-tradd-1 physical interaction relationship: participates_in CCO:I0018314 ! tnf_r1-tradd-1 physical interaction relationship: participates_in CCO:I0018489 ! tnfrsf1a-tradd-6 physical interaction relationship: participates_in CCO:I0018612 ! tnfrsf1a-tradd-2 physical interaction relationship: participates_in CCO:I0018767 ! tnfrsf1a-arts1 physical interaction relationship: participates_in CCO:I0018797 ! tnf_r1-tradd physical interaction relationship: participates_in CCO:I0019245 ! tnfrsf1a-tradd-7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005535 name: TNR1B_HUMAN def: "Tumor necrosis factor receptor superfamily member 1B precursor" [UniProtKB:P20333] synonym: "CD120b antigen" EXACT [UniProtKB:P20333] synonym: "Etanercept" EXACT [UniProtKB:P20333] synonym: "p75" EXACT [UniProtKB:P20333] synonym: "p80 TNF-alpha receptor" EXACT [UniProtKB:P20333] synonym: "TNF-R2" EXACT [UniProtKB:P20333] synonym: "Tumor necrosis factor receptor 2" EXACT [UniProtKB:P20333] synonym: "Tumor necrosis factor receptor type II" EXACT [UniProtKB:P20333] xref: EMBL:AAA36755.1 xref: EMBL:AAA59929.1 xref: EMBL:AAA63262.1 xref: EMBL:AAB19824.2 xref: EMBL:AAC50622.1 xref: EMBL:AAH52977.1 xref: EMBL:AAN72434.1 xref: EMBL:AAO89076.1 xref: EMBL:AAP88939.1 xref: EMBL:AAV38730.1 xref: EMBL:BAA89053.1 xref: EMBL:CAH73721.1 xref: UniProtKB:P20333 xref: UniProtKB:Q16042 xref: UniProtKB:Q6YI29 xref: UniProtKB:Q9UIH1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005804 ! TNFRSF1B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001358 ! tumor necrosis factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006415 ! tnfrsf1b-mad2l1 physical interaction relationship: participates_in CCO:I0006416 ! tnfrsf1b-q9bva1 physical interaction relationship: participates_in CCO:I0006442 ! tnfrsf1b-fancd2 physical interaction relationship: participates_in CCO:I0006443 ! tnfrsf1b-tnf physical interaction relationship: participates_in CCO:I0008521 ! tnfrsf1b-ddb1 physical interaction relationship: participates_in CCO:I0008551 ! tnfrsf1b-myh10 physical interaction relationship: participates_in CCO:I0017037 ! tnfrsf1b-pdcd8 physical interaction relationship: participates_in CCO:I0017038 ! tnfrsf1b-ipo8 physical interaction relationship: participates_in CCO:I0017039 ! tnfrsf1b-hspa9b physical interaction relationship: participates_in CCO:I0017040 ! tnfrsf1b-q9p035 physical interaction relationship: participates_in CCO:I0017041 ! tnfrsf1b-eef1a2 physical interaction relationship: participates_in CCO:I0017042 ! tnfrsf1b-atp5a1 physical interaction relationship: participates_in CCO:I0017043 ! tnfrsf1b-da24a23_2 physical interaction relationship: participates_in CCO:I0017044 ! tnfrsf1b-gbf1 physical interaction relationship: participates_in CCO:I0017045 ! tnfrsf1b-rps14 physical interaction relationship: participates_in CCO:I0017046 ! tnfrsf1b-myo6 physical interaction relationship: participates_in CCO:I0017047 ! tnfrsf1b-dnaja3 physical interaction relationship: participates_in CCO:I0017048 ! tnfrsf1b-flna physical interaction relationship: participates_in CCO:I0017049 ! tnfrsf1b-ipo7 physical interaction relationship: participates_in CCO:I0017050 ! tnfrsf1b-kiaa0219 physical interaction relationship: participates_in CCO:I0017051 ! tnfrsf1b-tra1 physical interaction relationship: participates_in CCO:I0017052 ! tnfrsf1b-myh9 physical interaction relationship: participates_in CCO:I0017053 ! tnfrsf1b-atp2a2 physical interaction relationship: participates_in CCO:I0017054 ! tnfrsf1b-cse1l physical interaction relationship: participates_in CCO:I0017055 ! tnfrsf1b-rps27 physical interaction relationship: participates_in CCO:I0017056 ! tnfrsf1b-mylk2 physical interaction relationship: participates_in CCO:I0017262 ! tnfrsf1b-traf2 physical interaction relationship: participates_in CCO:I0017504 ! tnfr2-traf1 physical interaction relationship: participates_in CCO:I0017509 ! tnfr2-traf2-2 physical interaction relationship: participates_in CCO:I0017682 ! tnfr2-traf2 physical interaction [Term] id: CCO:B0005536 name: TRAF6_HUMAN def: "TNF receptor-associated factor 6" [UniProtKB:Q9Y4K3] synonym: "Interleukin-1 signal transducer" EXACT [UniProtKB:Q9Y4K3] synonym: "RING finger protein 85" EXACT [UniProtKB:Q9Y4K3] xref: EMBL:AAB38751.1 xref: EMBL:AAH31052.1 xref: EMBL:AAO38054.1 xref: UniProtKB:Q8NEH5 xref: UniProtKB:Q9Y4K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005824 ! TRAF6_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006419 ! traf6-psmd8 physical interaction relationship: participates_in CCO:I0006420 ! traf6-psmd2 physical interaction relationship: participates_in CCO:I0006421 ! traf6-q9bva1 physical interaction relationship: participates_in CCO:I0006422 ! traf6-fancd2 physical interaction relationship: participates_in CCO:I0006428 ! traf6-psmd1 physical interaction relationship: participates_in CCO:I0008705 ! traf6-psmb6 physical interaction relationship: participates_in CCO:I0008706 ! traf6-psma4 physical interaction relationship: participates_in CCO:I0008707 ! traf6-psmc6 physical interaction relationship: participates_in CCO:I0008708 ! traf6-psmd4 physical interaction relationship: participates_in CCO:I0008709 ! traf6-psmc5 physical interaction relationship: participates_in CCO:I0008710 ! traf6-psmb2 physical interaction relationship: participates_in CCO:I0008711 ! traf6-psma1 physical interaction relationship: participates_in CCO:I0008712 ! traf6-psmd6 physical interaction relationship: participates_in CCO:I0008713 ! traf6-psmb5 physical interaction relationship: participates_in CCO:I0008714 ! traf6-psmc1 physical interaction relationship: participates_in CCO:I0008715 ! traf6-psmc2 physical interaction relationship: participates_in CCO:I0008716 ! traf6-psmc3 physical interaction relationship: participates_in CCO:I0008717 ! traf6-psmd12 physical interaction relationship: participates_in CCO:I0008718 ! traf6-psmd3 physical interaction relationship: participates_in CCO:I0008719 ! traf6-psmd7 physical interaction relationship: participates_in CCO:I0015345 ! traf2-traf6 physical interaction relationship: participates_in CCO:I0015926 ! irak-traf6 physical interaction relationship: participates_in CCO:I0015929 ! rank-traf6 physical interaction relationship: participates_in CCO:I0015993 ! st2-traf6-1 physical interaction relationship: participates_in CCO:I0016116 ! traf6-tab1-1 physical interaction relationship: participates_in CCO:I0016264 ! traf6-a20 physical interaction relationship: participates_in CCO:I0016265 ! traf6-cezanne physical interaction relationship: participates_in CCO:I0016266 ! traf6-trabid physical interaction relationship: participates_in CCO:I0017133 ! traf6-kpnb1 physical interaction relationship: participates_in CCO:I0017134 ! traf6-hspa1l physical interaction relationship: participates_in CCO:I0017135 ! traf6-hspa5 physical interaction relationship: participates_in CCO:I0017136 ! traf6-hspa8 physical interaction relationship: participates_in CCO:I0017137 ! traf6-hspa9b physical interaction relationship: participates_in CCO:I0017138 ! traf6-o75477 physical interaction relationship: participates_in CCO:I0017139 ! traf6-dnaja1 physical interaction relationship: participates_in CCO:I0017140 ! traf6-eef1a2 physical interaction relationship: participates_in CCO:I0017141 ! traf6-actg1 physical interaction relationship: participates_in CCO:I0017142 ! traf6-vcp physical interaction relationship: participates_in CCO:I0017143 ! traf6-rcn2 physical interaction relationship: participates_in CCO:I0017144 ! traf6-hadha physical interaction relationship: participates_in CCO:I0017145 ! traf6-hsp70_1 physical interaction relationship: participates_in CCO:I0017146 ! traf6-q9buf5 physical interaction relationship: participates_in CCO:I0017147 ! traf6-bri3bp physical interaction relationship: participates_in CCO:I0017148 ! traf6-psmd11 physical interaction relationship: participates_in CCO:I0017149 ! traf6-q9bv68 physical interaction relationship: participates_in CCO:I0017150 ! traf6-ipo7 physical interaction relationship: participates_in CCO:I0017151 ! traf6-adprt physical interaction relationship: participates_in CCO:I0017152 ! traf6-tuba2 physical interaction relationship: participates_in CCO:I0017153 ! traf6-atp2a2 physical interaction relationship: participates_in CCO:I0017203 ! traf6-kcnq1 physical interaction relationship: participates_in CCO:I0017204 ! traf6-psmd13 physical interaction relationship: participates_in CCO:I0017371 ! traf6-tiz-3 physical interaction relationship: participates_in CCO:I0017500 ! irak-traf6-1 physical interaction relationship: participates_in CCO:I0017501 ! traf6-tab1 physical interaction relationship: participates_in CCO:I0017698 ! traf6-tiz physical interaction relationship: participates_in CCO:I0017857 ! peli1-irak1-1 physical interaction relationship: participates_in CCO:I0017858 ! peli1-irak1-2 physical interaction relationship: participates_in CCO:I0017992 ! irak3-traf6-ex1 physical interaction relationship: participates_in CCO:I0017993 ! irak1-traf6-ex1 physical interaction relationship: participates_in CCO:I0017994 ! irak2-traf6-ex1 physical interaction relationship: participates_in CCO:I0018041 ! traf6-tirp physical interaction relationship: participates_in CCO:I0018618 ! traf6-tiz-2 colocalization relationship: participates_in CCO:I0018685 ! traf6-map3k14-1 physical interaction relationship: participates_in CCO:I0018686 ! traf6-map3k14-2 physical interaction relationship: participates_in CCO:I0018687 ! traf6-il1r1-1 physical interaction relationship: participates_in CCO:I0018707 ! cd40-traf6-2 direct interaction relationship: participates_in CCO:I0018792 ! xedar-traf6 physical interaction relationship: participates_in CCO:I0019494 ! traf6-tiz-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation [Term] id: CCO:B0005537 name: IKBB_HUMAN def: "NF-kappa-B inhibitor beta" [UniProtKB:Q15653] synonym: "I-kappa-B-beta" EXACT [UniProtKB:Q15653] synonym: "IkappaBbeta" EXACT [UniProtKB:Q15653] synonym: "IkB-B" EXACT [UniProtKB:Q15653] synonym: "IkB-beta" EXACT [UniProtKB:Q15653] synonym: "NF-kappa-BIB" EXACT [UniProtKB:Q15653] synonym: "Thyroid receptor-interacting protein 9" EXACT [UniProtKB:Q15653] synonym: "TR-interacting protein 9" EXACT [UniProtKB:Q15653] synonym: "TRIP-9" EXACT [UniProtKB:Q15653] xref: EMBL:AAC41742.1 xref: EMBL:AAH07197.1 xref: EMBL:AAH15528.1 xref: EMBL:AAP35389.1 xref: EMBL:AAU10088.1 xref: UniProtKB:Q15653 xref: UniProtKB:Q96BJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004872 ! NFKBIB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006425 ! nfkbib-kpna2 physical interaction relationship: participates_in CCO:I0006426 ! nfkbib-mcc physical interaction relationship: participates_in CCO:I0007400 ! mcc-nfkbib physical interaction relationship: participates_in CCO:I0016357 ! rel-nfkbib physical interaction relationship: participates_in CCO:I0016387 ! nfkbib-bag2 physical interaction relationship: participates_in CCO:I0016388 ! nfkbib-hspa1l physical interaction relationship: participates_in CCO:I0016389 ! nfkbib-hspa5 physical interaction relationship: participates_in CCO:I0016390 ! nfkbib-hspa8 physical interaction relationship: participates_in CCO:I0016391 ! nfkbib-s100a8 physical interaction relationship: participates_in CCO:I0016392 ! nfkbib-hspa9b physical interaction relationship: participates_in CCO:I0016393 ! nfkbib-slpi physical interaction relationship: participates_in CCO:I0016394 ! nfkbib-iqgap1 physical interaction relationship: participates_in CCO:I0016395 ! nfkbib-iars physical interaction relationship: participates_in CCO:I0016396 ! nfkbib-eprs physical interaction relationship: participates_in CCO:I0016397 ! nfkbib-nfkbib physical interaction relationship: participates_in CCO:I0016398 ! nfkbib-lyz physical interaction relationship: participates_in CCO:I0016399 ! nfkbib-actg1 physical interaction relationship: participates_in CCO:I0016400 ! nfkbib-vcp physical interaction relationship: participates_in CCO:I0016401 ! nfkbib-tbp physical interaction relationship: participates_in CCO:I0016402 ! nfkbib-cltc physical interaction relationship: participates_in CCO:I0016403 ! nfkbib-rpl35a physical interaction relationship: participates_in CCO:I0016404 ! nfkbib-rpl7 physical interaction relationship: participates_in CCO:I0016405 ! nfkbib-hsp70_1 physical interaction relationship: participates_in CCO:I0016406 ! nfkbib-sec8l1 physical interaction relationship: participates_in CCO:I0016407 ! nfkbib-srprb physical interaction relationship: participates_in CCO:I0016408 ! nfkbib-nfkb2 physical interaction relationship: participates_in CCO:I0016409 ! nfkbib-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016410 ! nfkbib-q8nhw5 physical interaction relationship: participates_in CCO:I0016411 ! nfkbib-ok/sw_cl_108 physical interaction relationship: participates_in CCO:I0016412 ! nfkbib-znrd1 physical interaction relationship: participates_in CCO:I0016413 ! nfkbib-polr1b physical interaction relationship: participates_in CCO:I0016414 ! nfkbib-hnrpu physical interaction relationship: participates_in CCO:I0016415 ! nfkbib-sfpq physical interaction relationship: participates_in CCO:I0016416 ! nfkbib-dsp physical interaction relationship: participates_in CCO:I0016417 ! nfkbib-q8iwp9 physical interaction relationship: participates_in CCO:I0016418 ! nfkbib-hspca physical interaction relationship: participates_in CCO:I0016419 ! nfkbib-ncl physical interaction relationship: participates_in CCO:I0016420 ! nfkbib-tuba2 physical interaction relationship: participates_in CCO:I0016421 ! nfkbib-tuba1 physical interaction relationship: participates_in CCO:I0016436 ! chuk-nfkbib physical interaction relationship: participates_in CCO:I0017160 ! nfkbia-nfkbib physical interaction relationship: participates_in CCO:I0017165 ! nfkbib-ase_1 physical interaction relationship: participates_in CCO:I0017166 ! nfkbib-fbxw1b physical interaction relationship: participates_in CCO:I0017167 ! nfkbib-rel physical interaction relationship: participates_in CCO:I0017168 ! nfkbib-chuk physical interaction relationship: participates_in CCO:I0017169 ! nfkbib-ikbkb physical interaction relationship: participates_in CCO:I0017170 ! nfkbib-ikbkg physical interaction relationship: participates_in CCO:I0017171 ! nfkbib-iqgap2 physical interaction relationship: participates_in CCO:I0017172 ! nfkbib-lrpprc physical interaction relationship: participates_in CCO:I0017173 ! nfkbib-mtif2 physical interaction relationship: participates_in CCO:I0017174 ! nfkbib-nfkb1 physical interaction relationship: participates_in CCO:I0017175 ! nfkbib-rasal2 physical interaction relationship: participates_in CCO:I0017176 ! nfkbib-q9gzs1 physical interaction relationship: participates_in CCO:I0017177 ! nfkbib-pdcd2 physical interaction relationship: participates_in CCO:I0017178 ! nfkbib-polr1a physical interaction relationship: participates_in CCO:I0017179 ! nfkbib-polr1b-1 physical interaction relationship: participates_in CCO:I0017180 ! nfkbib-polr1d physical interaction relationship: participates_in CCO:I0017181 ! nfkbib-polr2h physical interaction relationship: participates_in CCO:I0017182 ! nfkbib-polr2l physical interaction relationship: participates_in CCO:I0017183 ! nfkbib-polr1c physical interaction relationship: participates_in CCO:I0017194 ! nfkb2-nfkbib-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012343 ! IKBB_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0012344 ! IKBB_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0041150 ! IKBB_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0041151 ! IKBB_HUMAN-Phosphoserine315 [Term] id: CCO:B0005538 name: IKBE_HUMAN def: "NF-kappa-B inhibitor epsilon" [UniProtKB:O00221] synonym: "I-kappa-B-epsilon" EXACT [UniProtKB:O00221] synonym: "IkappaBepsilon" EXACT [UniProtKB:O00221] synonym: "IkB-E" EXACT [UniProtKB:O00221] synonym: "IkB-epsilon" EXACT [UniProtKB:O00221] synonym: "NF-kappa-BIE" EXACT [UniProtKB:O00221] xref: EMBL:AAC51216.1 xref: EMBL:CAI20103.1 xref: EMBL:EAX04262.1 xref: UniProtKB:O00221 xref: UniProtKB:Q5T9V9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004873 ! NFKBIE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006429 ! nfkbie-ppp6c physical interaction relationship: participates_in CCO:I0008703 ! nfkbie-psma5 physical interaction relationship: participates_in CCO:I0008704 ! nfkbie-psme3 physical interaction relationship: participates_in CCO:I0016352 ! rel-nfkbie physical interaction relationship: participates_in CCO:I0016422 ! nfkbie-ikbkg physical interaction relationship: participates_in CCO:I0016423 ! nfkbie-hspa9b physical interaction relationship: participates_in CCO:I0016424 ! nfkbie-ruvbl2 physical interaction relationship: participates_in CCO:I0016425 ! nfkbie-nfkb1 physical interaction relationship: participates_in CCO:I0016426 ! nfkbie-vcp physical interaction relationship: participates_in CCO:I0016427 ! nfkbie-nfkb2 physical interaction relationship: participates_in CCO:I0016428 ! nfkbie-arhgef2 physical interaction relationship: participates_in CCO:I0016429 ! nfkbie-sfpq physical interaction relationship: participates_in CCO:I0016430 ! nfkbie-hspca physical interaction relationship: participates_in CCO:I0016787 ! nfkb2-nfkbie physical interaction relationship: participates_in CCO:I0016862 ! relb-nfkbie physical interaction relationship: participates_in CCO:I0017184 ! nfkbie-fbxw1b physical interaction relationship: participates_in CCO:I0017185 ! nfkbie-rel physical interaction relationship: participates_in CCO:I0017186 ! nfkbie-chuk physical interaction relationship: transforms_into CCO:B0067063 ! IKBE_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0067064 ! IKBE_HUMAN-Phosphoserine161 [Term] id: CCO:B0005539 name: IKKA_HUMAN def: "Inhibitor of nuclear factor kappa-B kinase subunit alpha" [UniProtKB:O15111] synonym: "Conserved helix-loop-helix ubiquitous kinase" EXACT [UniProtKB:O15111] synonym: "EC 2.7.11.10" EXACT [UniProtKB:O15111] synonym: "I kappa-B kinase alpha" EXACT [UniProtKB:O15111] synonym: "I-kappa-B kinase 1" EXACT [UniProtKB:O15111] synonym: "IkappaB kinase" EXACT [UniProtKB:O15111] synonym: "IkBKA" EXACT [UniProtKB:O15111] synonym: "IKK-A" EXACT [UniProtKB:O15111] synonym: "IKK-alpha" EXACT [UniProtKB:O15111] synonym: "IKK1" EXACT [UniProtKB:O15111] synonym: "NFKBIKA" EXACT [UniProtKB:O15111] synonym: "Nuclear factor NF-kappa-B inhibitor kinase alpha" EXACT [UniProtKB:O15111] xref: EMBL:AAC50713.1 xref: EMBL:AAC51662.1 xref: EMBL:AAC51671.1 xref: EMBL:AAD08996.1 xref: EMBL:AAT49098.1 xref: EMBL:CAH72401.1 xref: UniProtKB:O14666 xref: UniProtKB:O15111 xref: UniProtKB:Q13132 xref: UniProtKB:Q5W0I4 xref: UniProtKB:Q92467 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004874 ! CHUK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006430 ! chuk-cdc37 physical interaction relationship: participates_in CCO:I0008542 ! chuk-myh10 physical interaction relationship: participates_in CCO:I0015930 ! ikbkg-chuk-3 physical interaction relationship: participates_in CCO:I0015931 ! ikbkg-chuk-1 physical interaction relationship: participates_in CCO:I0016117 ! ikk-nik physical interaction relationship: participates_in CCO:I0016431 ! chuk-ikbkg physical interaction relationship: participates_in CCO:I0016432 ! chuk-chuk physical interaction relationship: participates_in CCO:I0016433 ! chuk-capza1 physical interaction relationship: participates_in CCO:I0016434 ! chuk-hspa9b physical interaction relationship: participates_in CCO:I0016435 ! chuk-eef1a2 physical interaction relationship: participates_in CCO:I0016436 ! chuk-nfkbib physical interaction relationship: participates_in CCO:I0016437 ! chuk-actg1 physical interaction relationship: participates_in CCO:I0016438 ! chuk-cltc physical interaction relationship: participates_in CCO:I0016439 ! chuk-hsp70_1 physical interaction relationship: participates_in CCO:I0016440 ! chuk-myh14 physical interaction relationship: participates_in CCO:I0016441 ! chuk-myh9 physical interaction relationship: participates_in CCO:I0016442 ! chuk-tpm3 physical interaction relationship: participates_in CCO:I0016443 ! chuk-myl6 physical interaction relationship: participates_in CCO:I0016444 ! chuk-tuba2 physical interaction relationship: participates_in CCO:I0016445 ! chuk-mlcb physical interaction relationship: participates_in CCO:I0016446 ! chuk-myo1d physical interaction relationship: participates_in CCO:I0016451 ! ikbkb-chuk physical interaction relationship: participates_in CCO:I0016672 ! map3k3-chuk physical interaction relationship: participates_in CCO:I0016857 ! relb-chuk physical interaction relationship: participates_in CCO:I0017162 ! nfkbia-chuk physical interaction relationship: participates_in CCO:I0017168 ! nfkbib-chuk physical interaction relationship: participates_in CCO:I0017186 ! nfkbie-chuk physical interaction relationship: participates_in CCO:I0017195 ! nfkb2-chuk-1 physical interaction relationship: participates_in CCO:I0017205 ! chuk-fkbp5 physical interaction relationship: participates_in CCO:I0017206 ! chuk-hspca physical interaction relationship: participates_in CCO:I0017207 ! chuk-hspcb physical interaction relationship: participates_in CCO:I0017208 ! chuk-ikbkb physical interaction relationship: participates_in CCO:I0017219 ! ikbkg-chuk physical interaction relationship: participates_in CCO:I0017243 ! map3k14-chuk physical interaction relationship: participates_in CCO:I0017388 ! ikbkb-ikbkg-2 physical interaction relationship: participates_in CCO:I0017702 ! ikk_gamma-ikk_alpha physical interaction relationship: participates_in CCO:I0017782 ! chuk-mavs-1 physical interaction relationship: participates_in CCO:I0018043 ! ikk_complex physical interaction relationship: participates_in CCO:I0018211 ! ncoa3-crebbp-ncoa2-1 physical interaction relationship: participates_in CCO:I0018241 ! ikbkb-nfkbia-5 physical interaction relationship: participates_in CCO:I0018386 ! ikbkb-5 physical interaction relationship: participates_in CCO:I0018497 ! ikbkg-chuk-2 physical interaction relationship: participates_in CCO:I0018511 ! rela-chuk-1 physical interaction relationship: participates_in CCO:I0018527 ! ncoa3-chuk physical interaction relationship: participates_in CCO:I0018585 ! fkbp5-chuk physical interaction relationship: participates_in CCO:I0018621 ! chuk-map3k14-2 phosphorylation relationship: participates_in CCO:I0018628 ! chuk-nfkbia-1 phosphorylation relationship: participates_in CCO:I0018630 ! ikbkb-chuk-1 physical interaction relationship: participates_in CCO:I0018631 ! chuk-map3k14-1 phosphorylation relationship: participates_in CCO:I0018671 ! ikka-src-2 physical interaction relationship: participates_in CCO:I0018672 ! ikka-src-1 physical interaction relationship: participates_in CCO:P0000770 ! I-kappaB phosphorylation relationship: transforms_into CCO:B0012347 ! IKKA_HUMAN-Phosphothreonine23 relationship: transforms_into CCO:B0012348 ! IKKA_HUMAN-Phosphoserine176 [Term] id: CCO:B0005540 name: ERBB2_HUMAN def: "Receptor tyrosine-protein kinase erbB-2 precursor" [UniProtKB:P04626] synonym: "C-erbB-2" EXACT [UniProtKB:P04626] synonym: "CD340 antigen" EXACT [UniProtKB:P04626] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P04626] synonym: "MLN 19" EXACT [UniProtKB:P04626] synonym: "NEU proto-oncogene" EXACT [UniProtKB:P04626] synonym: "p185erbB2" EXACT [UniProtKB:P04626] synonym: "Tyrosine kinase-type cell surface receptor HER2" EXACT [UniProtKB:P04626] xref: EMBL:AAA35808.1 xref: EMBL:AAA35809.1 xref: EMBL:AAA35978.1 xref: EMBL:AAA58637.1 xref: EMBL:AAA75493.1 xref: EMBL:AAC37531.1 xref: EMBL:AAO18082.1 xref: EMBL:CAA27060.1 xref: UniProtKB:P04626 xref: UniProtKB:Q14256 xref: UniProtKB:Q6LDV1 xref: UniProtKB:Q9UMK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004577 ! ERBB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006444 ! erbb2-egfr physical interaction relationship: participates_in CCO:I0006445 ! erbb2-egfr-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007304 ! erbb2-egfr-2 physical interaction relationship: participates_in CCO:I0007305 ! erbb2-egfr-3 physical interaction relationship: participates_in CCO:I0007591 ! erbb1-erbb2-1 physical interaction relationship: participates_in CCO:I0007817 ! erbb2-egfr-4 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0015951 ! erbb2-pik3c2b-2 direct interaction relationship: participates_in CCO:I0016315 ! erbb3-erbb2-3 physical interaction relationship: participates_in CCO:I0018249 ! erbb4-erbb2 physical interaction relationship: participates_in CCO:I0018529 ! erbb3-erbb2-2 physical interaction relationship: participates_in CCO:I0018865 ! erbb3-erbb2-1 physical interaction relationship: participates_in CCO:I0018867 ! erbb4-erbb2-1 physical interaction relationship: participates_in CCO:I0019316 ! erbb2-erbb2 physical interaction relationship: participates_in CCO:I0019389 ! erbb2-pik3c2a-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001084 ! phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001776 ! negative regulation of immature T cell proliferation in the thymus relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: transforms_into CCO:B0011738 ! ERBB2_HUMAN-Phosphotyrosine1139 relationship: transforms_into CCO:B0011739 ! ERBB2_HUMAN-Phosphotyrosine1196 relationship: transforms_into CCO:B0011740 ! ERBB2_HUMAN-Phosphotyrosine1248 relationship: transforms_into CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 [Term] id: CCO:B0005541 name: UCHL1_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase isozyme L1" [UniProtKB:P09936] synonym: "EC 3.4.19.12" EXACT [UniProtKB:P09936] synonym: "EC 6.-.-.-" EXACT [UniProtKB:P09936] synonym: "Neuron cytoplasmic protein 9.5" EXACT [UniProtKB:P09936] synonym: "PGP 9.5" EXACT [UniProtKB:P09936] synonym: "PGP9.5" EXACT [UniProtKB:P09936] synonym: "Ubiquitin thioesterase L1" EXACT [UniProtKB:P09936] synonym: "UCH-L1" EXACT [UniProtKB:P09936] xref: EMBL:AAD09172.1 xref: EMBL:AAH00332.1 xref: EMBL:AAH05117.1 xref: EMBL:AAH06305.1 xref: EMBL:CAA28443.1 xref: EMBL:CAA35249.1 xref: UniProtKB:P09936 xref: UniProtKB:Q71UM0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005875 ! UCHL1_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001792 ! omega peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006462 ! cdkn1b-uchl1 physical interaction relationship: participates_in CCO:I0006789 ! uchl1-ube2i physical interaction relationship: participates_in CCO:I0007045 ! cdn1b-uchl1 colocalization relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction [Term] id: CCO:B0005542 name: TGFR2_HUMAN def: "TGF-beta receptor type-2 precursor" [UniProtKB:P37173] synonym: "EC 2.7.11.30" EXACT [UniProtKB:P37173] synonym: "TbetaR-II" EXACT [UniProtKB:P37173] synonym: "TGF-beta receptor type II" EXACT [UniProtKB:P37173] synonym: "TGF-beta type II receptor" EXACT [UniProtKB:P37173] synonym: "TGFR-2" EXACT [UniProtKB:P37173] synonym: "Transforming growth factor-beta receptor type II" EXACT [UniProtKB:P37173] xref: EMBL:AAA61164.1 xref: EMBL:AAB17553.1 xref: EMBL:AAB40916.1 xref: EMBL:AAT70724.1 xref: EMBL:BAA05673.1 xref: EMBL:BAA09332.1 xref: UniProtKB:P37173 xref: UniProtKB:Q15580 xref: UniProtKB:Q6DKT6 xref: UniProtKB:Q99474 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005776 ! TGFBR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006468 ! daxx-tgfbr2-1 physical interaction relationship: participates_in CCO:I0006840 ! tgfbr2-daxx-1 physical interaction relationship: participates_in CCO:I0007826 ! tgfb3-tgfbr2-1 direct interaction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0014349 ! TGFR2_HUMAN-Phosphoserine548 [Term] id: CCO:B0005543 name: AVR2A_HUMAN def: "Activin receptor type-2A precursor" [UniProtKB:P27037] synonym: "Activin receptor type IIA" EXACT [UniProtKB:P27037] synonym: "ACTR-IIA" EXACT [UniProtKB:P27037] synonym: "ACTRIIA" EXACT [UniProtKB:P27037] synonym: "EC 2.7.11.30" EXACT [UniProtKB:P27037] xref: EMBL:AAA35504.1 xref: EMBL:AAH67417.1 xref: EMBL:AAH67418.1 xref: EMBL:AAH69707.1 xref: EMBL:AAX93050.1 xref: EMBL:BAA06548.1 xref: EMBL:CAA44245.1 xref: EMBL:CAA44839.1 xref: UniProtKB:P27037 xref: UniProtKB:Q53TH4 xref: UniProtKB:Q6NWV2 xref: UniProtKB:Q92474 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004132 ! ACVR2A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003510 ! activin receptor activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005879 ! protein self-association relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007319 ! activin binding relationship: has_function CCO:F0007320 ! inhibin beta-A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006469 ! daxx-acvr2-1 physical interaction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001714 ! activin receptor signaling pathway relationship: participates_in CCO:P0001717 ! positive regulation of activin receptor signaling pathway relationship: participates_in CCO:P0002462 ! positive regulation of erythrocyte differentiation relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0003228 ! Sertoli cell proliferation [Term] id: CCO:B0005545 name: NRX1A_HUMAN def: "Neurexin-1-alpha precursor" [UniProtKB:Q9ULB1] synonym: "Neurexin I-alpha" EXACT [UniProtKB:Q9ULB1] xref: EMBL:AAF03536.1 xref: EMBL:AAG38120.1 xref: EMBL:AAG59602.1 xref: EMBL:AAG59642.1 xref: EMBL:AAK06387.1 xref: EMBL:AAY14894.1 xref: EMBL:AAY14944.1 xref: EMBL:BAA25504.2 xref: EMBL:BAA87821.1 xref: UniProtKB:O60323 xref: UniProtKB:Q53TJ9 xref: UniProtKB:Q53TQ1 xref: UniProtKB:Q9C079 xref: UniProtKB:Q9C080 xref: UniProtKB:Q9C081 xref: UniProtKB:Q9H3M2 xref: UniProtKB:Q9UDM6 xref: UniProtKB:Q9ULB1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005215 ! NRXN1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006472 ! kiaa0578-kiaa0865 physical interaction relationship: participates_in CCO:I0017286 ! kiaa0578-kiaa0440 physical interaction [Term] id: CCO:B0005546 name: CELR3_HUMAN def: "Cadherin EGF LAG seven-pass G-type receptor 3 precursor" [UniProtKB:Q9NYQ7] synonym: "Epidermal growth factor-like 1" EXACT [UniProtKB:Q9NYQ7] synonym: "Flamingo homolog 1" EXACT [UniProtKB:Q9NYQ7] synonym: "hFmi1" EXACT [UniProtKB:Q9NYQ7] synonym: "Multiple epidermal growth factor-like domains 2" EXACT [UniProtKB:Q9NYQ7] xref: EMBL:AAF61929.1 xref: EMBL:BAA32464.1 xref: UniProtKB:O75092 xref: UniProtKB:Q9NYQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004320 ! CELSR3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006473 ! celsr3-bpag1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0011132 ! CELR3_HUMAN-3-hydroxyaspartate1963 [Term] id: CCO:B0005547 name: PLXB3_HUMAN def: "Plexin-B3 precursor" [UniProtKB:Q9ULL4] xref: EMBL:AAG01376.1 xref: EMBL:BAA86520.1 xref: UniProtKB:Q9HDA4 xref: UniProtKB:Q9ULL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005342 ! PLXNB3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006474 ! kiaa1206-cul7 physical interaction relationship: participates_in CCO:I0006475 ! kiaa1206-parc physical interaction relationship: participates_in CCO:I0017292 ! kiaa1206-spock2 physical interaction relationship: participates_in CCO:I0017293 ! kiaa1206-arhgef11 physical interaction relationship: participates_in CCO:I0017294 ! kiaa1206-aip1 physical interaction relationship: participates_in CCO:I0017295 ! kiaa1206-btbd3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005549 name: MEG10_HUMAN def: "Multiple epidermal growth factor-like domains 10 precursor" [UniProtKB:Q96KG7] synonym: "Multiple EGF-like-domains 10" EXACT [UniProtKB:Q96KG7] xref: EMBL:AAH20198.1 xref: EMBL:AAI52479.1 xref: EMBL:BAB47409.2 xref: EMBL:CAH18275.1 xref: EMBL:EAW62406.1 xref: UniProtKB:Q68DE5 xref: UniProtKB:Q8WUL3 xref: UniProtKB:Q96KG7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005080 ! MEGF10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: participates_in CCO:I0017303 ! megf10-grb10 physical interaction [Term] id: CCO:B0005550 name: RGL1_HUMAN def: "Ral guanine nucleotide dissociation stimulator-like 1" [UniProtKB:Q9NZL6] synonym: "RalGDS-like 1" EXACT [UniProtKB:Q9NZL6] xref: EMBL:AAF67280.1 xref: EMBL:AAF67281.1 xref: EMBL:AAG14400.1 xref: EMBL:AAG14401.1 xref: EMBL:BAA76803.1 xref: EMBL:CAB45716.1 xref: UniProtKB:Q9HBY3 xref: UniProtKB:Q9HBY4 xref: UniProtKB:Q9NZL5 xref: UniProtKB:Q9NZL6 xref: UniProtKB:Q9UG43 xref: UniProtKB:Q9Y2G6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005479 ! RGL1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001833 ! Ral guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0006478 ! rlg1-hras physical interaction relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0017305 ! hras-rgl1 physical interaction relationship: participates_in CCO:I0017306 ! rit1-rgl1 physical interaction relationship: participates_in CCO:I0017307 ! rgl1-rit1 physical interaction relationship: participates_in CCO:I0017308 ! rlg1-rit2 physical interaction relationship: participates_in CCO:I0018586 ! rit-af6 physical interaction relationship: participates_in CCO:I0018587 ! rit2-af6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0069909 ! RGL1_HUMAN-Phosphothreonine670 [Term] id: CCO:B0005551 name: ARNT_HUMAN def: "Aryl hydrocarbon receptor nuclear translocator" [UniProtKB:P27540] synonym: "ARNT protein" EXACT [UniProtKB:P27540] synonym: "Dioxin receptor, nuclear translocator" EXACT [UniProtKB:P27540] synonym: "HIF-1 beta" EXACT [UniProtKB:P27540] synonym: "Hypoxia-inducible factor 1 beta" EXACT [UniProtKB:P27540] xref: EMBL:AAA51777.1 xref: EMBL:AAQ96598.1 xref: EMBL:CAC21446.1 xref: UniProtKB:P27540 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004099 ! ARNT_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001375 ! aryl hydrocarbon receptor nuclear translocator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003602 ! aryl hydrocarbon receptor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006479 ! ahr-arnt-3 physical interaction relationship: participates_in CCO:I0006480 ! ahr-arnt-4 physical interaction relationship: participates_in CCO:I0006545 ! ahr-arnt-1 physical interaction relationship: participates_in CCO:I0006547 ! ahr-arnt-2 physical interaction relationship: participates_in CCO:I0017386 ! arnt-erap_140-1 physical interaction relationship: participates_in CCO:I0017387 ! arnt-ncor2-1 physical interaction relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001356 ! positive regulation of vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002250 ! regulation of transcription from RNA polymerase II promoter in response to oxidative stress relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002462 ! positive regulation of erythrocyte differentiation relationship: participates_in CCO:P0002569 ! positive regulation of glycolysis relationship: participates_in CCO:P0002746 ! positive regulation of hormone biosynthetic process [Term] id: CCO:B0005552 name: NCOA7_HUMAN def: "Nuclear receptor coactivator 7" [UniProtKB:Q8NI08] synonym: "140 kDa estrogen receptor-associated protein" EXACT [UniProtKB:Q8NI08] synonym: "Estrogen nuclear receptor coactivator 1" EXACT [UniProtKB:Q8NI08] xref: EMBL:AAH36461.1 xref: EMBL:AAH71782.1 xref: EMBL:AAM27392.1 xref: EMBL:BAC04402.1 xref: EMBL:BAE45732.1 xref: EMBL:CAD89948.1 xref: EMBL:CAD97627.1 xref: EMBL:CAI20072.1 xref: EMBL:CAI42386.1 xref: EMBL:CAI42397.1 xref: UniProtKB:Q3LID6 xref: UniProtKB:Q4G0V1 xref: UniProtKB:Q5TF95 xref: UniProtKB:Q6IPQ4 xref: UniProtKB:Q6NE83 xref: UniProtKB:Q86T89 xref: UniProtKB:Q8N1W4 xref: UniProtKB:Q8NI08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005161 ! NCOA7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006479 ! ahr-arnt-3 physical interaction relationship: participates_in CCO:I0006544 ! ahr-erap_140-1 physical interaction relationship: participates_in CCO:I0006545 ! ahr-arnt-1 physical interaction relationship: participates_in CCO:I0017386 ! arnt-erap_140-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068489 ! NCOA7_HUMAN-Phosphothreonine134 relationship: transforms_into CCO:B0068490 ! NCOA7_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0068491 ! NCOA7_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0068492 ! NCOA7_HUMAN-Phosphothreonine210 relationship: transforms_into CCO:B0068493 ! NCOA7_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0068494 ! NCOA7_HUMAN-Phosphoserine441 [Term] id: CCO:B0005553 name: NCOR2_HUMAN def: "Nuclear receptor corepressor 2" [UniProtKB:Q9Y618] synonym: "CTG repeat protein 26" EXACT [UniProtKB:Q9Y618] synonym: "N-CoR2" EXACT [UniProtKB:Q9Y618] synonym: "Silencing mediator of retinoic acid and thyroid hormone receptor" EXACT [UniProtKB:Q9Y618] synonym: "SMAP270" EXACT [UniProtKB:Q9Y618] synonym: "SMRT" EXACT [UniProtKB:Q9Y618] synonym: "SMRTe" EXACT [UniProtKB:Q9Y618] synonym: "T3 receptor-associating factor" EXACT [UniProtKB:Q9Y618] synonym: "Thyroid-, retinoic-acid-receptor-associated corepressor" EXACT [UniProtKB:Q9Y618] synonym: "TRAC" EXACT [UniProtKB:Q9Y618] xref: EMBL:AAB50847.1 xref: EMBL:AAB91446.1 xref: EMBL:AAB91452.1 xref: EMBL:AAC50236.1 xref: EMBL:AAD20946.1 xref: EMBL:AAD22973.1 xref: UniProtKB:O00613 xref: UniProtKB:O15416 xref: UniProtKB:O15421 xref: UniProtKB:Q13354 xref: UniProtKB:Q9Y5U0 xref: UniProtKB:Q9Y618 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005162 ! NCOR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006480 ! ahr-arnt-4 physical interaction relationship: participates_in CCO:I0006546 ! ahr-ncor2-1 physical interaction relationship: participates_in CCO:I0006547 ! ahr-arnt-2 physical interaction relationship: participates_in CCO:I0007582 ! bcl6-hdac4 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0015948 ! skiip-ncor2-1 physical interaction relationship: participates_in CCO:I0015949 ! skiip-ncor2-2 physical interaction relationship: participates_in CCO:I0017387 ! arnt-ncor2-1 physical interaction relationship: participates_in CCO:I0017441 ! tnik-ncor2 physical interaction relationship: participates_in CCO:I0017659 ! ncor2-hdac1-1 physical interaction relationship: participates_in CCO:I0017664 ! ncor2-hdac10-1 physical interaction relationship: participates_in CCO:I0018653 ! rbpsuh-ncor2-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013110 ! NCOR2_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0013111 ! NCOR2_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0013112 ! NCOR2_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0013113 ! NCOR2_HUMAN-Phosphothreonine553 relationship: transforms_into CCO:B0013114 ! NCOR2_HUMAN-Phosphoserine554 relationship: transforms_into CCO:B0013115 ! NCOR2_HUMAN-Phosphoserine939 relationship: transforms_into CCO:B0013116 ! NCOR2_HUMAN-Phosphoserine1253 relationship: transforms_into CCO:B0013117 ! NCOR2_HUMAN-Phosphothreonine1383 relationship: transforms_into CCO:B0013118 ! NCOR2_HUMAN-Phosphoserine1576 relationship: transforms_into CCO:B0013119 ! NCOR2_HUMAN-Phosphoserine1974 relationship: transforms_into CCO:B0013120 ! NCOR2_HUMAN-Phosphoserine2008 relationship: transforms_into CCO:B0013121 ! NCOR2_HUMAN-Phosphoserine2049 relationship: transforms_into CCO:B0013122 ! NCOR2_HUMAN-Phosphoserine2057 relationship: transforms_into CCO:B0013123 ! NCOR2_HUMAN-Phosphoserine2061 relationship: transforms_into CCO:B0013124 ! NCOR2_HUMAN-Phosphoserine2197 relationship: transforms_into CCO:B0013125 ! NCOR2_HUMAN-Phosphoserine2200 relationship: transforms_into CCO:B0013126 ! NCOR2_HUMAN-Phosphoserine2261 relationship: transforms_into CCO:B0013127 ! NCOR2_HUMAN-Phosphoserine2455 relationship: transforms_into CCO:B0013128 ! NCOR2_HUMAN-Phosphoserine2514 relationship: transforms_into CCO:B0013129 ! NCOR2_HUMAN-Phosphoserine2516 relationship: transforms_into CCO:B0036018 ! NCOR2_HUMAN-Phosphoserine956 relationship: transforms_into CCO:B0048332 ! NCOR2_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0068509 ! NCOR2_HUMAN-Phosphothreonine156 relationship: transforms_into CCO:B0068510 ! NCOR2_HUMAN-Phosphoserine745 relationship: transforms_into CCO:B0068511 ! NCOR2_HUMAN-Phosphoserine746 relationship: transforms_into CCO:B0068512 ! NCOR2_HUMAN-Phosphoserine750 relationship: transforms_into CCO:B0068513 ! NCOR2_HUMAN-Phosphoserine753 relationship: transforms_into CCO:B0068514 ! NCOR2_HUMAN-Phosphoserine1251 relationship: transforms_into CCO:B0068515 ! NCOR2_HUMAN-Phosphoserine1479 relationship: transforms_into CCO:B0068516 ! NCOR2_HUMAN-Phosphotyrosine2043 relationship: transforms_into CCO:B0068517 ! NCOR2_HUMAN-Phosphoserine2063 relationship: transforms_into CCO:B0068518 ! NCOR2_HUMAN-Phosphothreonine2065 relationship: transforms_into CCO:B0068519 ! NCOR2_HUMAN-Phosphoserine2226 [Term] id: CCO:B0005554 name: EXOS4_HUMAN def: "Exosome complex exonuclease RRP41" [UniProtKB:Q9NPD3] synonym: "EC 3.1.13.-" EXACT [UniProtKB:Q9NPD3] synonym: "Exosome component 4" EXACT [UniProtKB:Q9NPD3] synonym: "p12A" EXACT [UniProtKB:Q9NPD3] synonym: "Ribosomal RNA-processing protein 41" EXACT [UniProtKB:Q9NPD3] xref: EMBL:AAF82134.1 xref: EMBL:AAH02777.1 xref: EMBL:BAA91279.1 xref: UniProtKB:Q9NPD3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004598 ! EXOSC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006481 ! exosc4-nek1 physical interaction relationship: transforms_into CCO:B0011811 ! EXOS4_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005555 name: EXOS5_HUMAN def: "Exosome complex exonuclease RRP46" [UniProtKB:Q9NQT4] synonym: "Chronic myelogenous leukemia tumor antigen 28" EXACT [UniProtKB:Q9NQT4] synonym: "EC 3.1.13.-" EXACT [UniProtKB:Q9NQT4] synonym: "Exosome component 5" EXACT [UniProtKB:Q9NQT4] synonym: "p12B" EXACT [UniProtKB:Q9NQT4] synonym: "Ribosomal RNA-processing protein 46" EXACT [UniProtKB:Q9NQT4] xref: EMBL:AAF82135.1 xref: EMBL:AAH07742.1 xref: EMBL:AAI07697.1 xref: EMBL:AAM75154.1 xref: UniProtKB:Q32Q81 xref: UniProtKB:Q8NG16 xref: UniProtKB:Q96I89 xref: UniProtKB:Q9NQT4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004599 ! EXOSC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006482 ! exosc5-cdk5rap1 physical interaction relationship: participates_in CCO:I0017313 ! exosc5-sfpq physical interaction relationship: participates_in CCO:I0017314 ! exosc5-znf558 physical interaction relationship: transforms_into CCO:B0011812 ! EXOS5_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0011813 ! EXOS5_HUMAN-Phosphoserine27 [Term] id: CCO:B0005556 name: EXOS8_HUMAN def: "Exosome complex exonuclease RRP43" [UniProtKB:Q96B26] synonym: "EC 3.1.13.-" EXACT [UniProtKB:Q96B26] synonym: "Exosome component 8" EXACT [UniProtKB:Q96B26] synonym: "Opa-interacting protein 2" EXACT [UniProtKB:Q96B26] synonym: "p9" EXACT [UniProtKB:Q96B26] synonym: "Ribosomal RNA-processing protein 43" EXACT [UniProtKB:Q96B26] xref: EMBL:AAC39558.1 xref: EMBL:AAH20773.1 xref: EMBL:CAI14013.1 xref: EMBL:EAX08581.1 xref: UniProtKB:O43480 xref: UniProtKB:Q5TBA5 xref: UniProtKB:Q96B26 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004600 ! EXOSC8_human relationship: has_function CCO:F0000034 ! 3'-5'-exoribonuclease activity relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000034 ! exosome (RNase complex) relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006483 ! exosc8-ches1 physical interaction relationship: participates_in CCO:I0015888 ! exosc8-zfp36 physical interaction relationship: participates_in CCO:I0015893 ! xrn2-exosc8 physical interaction relationship: participates_in CCO:I0017315 ! exosc8-kiaa1604 physical interaction [Term] id: CCO:B0005557 name: EXOS3_HUMAN def: "Exosome complex exonuclease RRP40" [UniProtKB:Q9NQT5] synonym: "EC 3.1.13.-" EXACT [UniProtKB:Q9NQT5] synonym: "Exosome component 3" EXACT [UniProtKB:Q9NQT5] synonym: "p10" EXACT [UniProtKB:Q9NQT5] synonym: "Ribosomal RNA-processing protein 40" EXACT [UniProtKB:Q9NQT5] xref: EMBL:AAD34097.1 xref: EMBL:AAF82133.1 xref: EMBL:AAH02437.1 xref: EMBL:AAH08880.1 xref: UniProtKB:Q9NQT5 xref: UniProtKB:Q9Y3A8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004597 ! EXOSC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006484 ! exosc3-cdk5rap1 physical interaction relationship: transforms_into CCO:B0011810 ! EXOS3_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005559 name: SNX9_HUMAN def: "Sorting nexin-9" [UniProtKB:Q9Y5X1] synonym: "Protein SDP1" EXACT [UniProtKB:Q9Y5X1] synonym: "SH3 and PX domain-containing protein 1" EXACT [UniProtKB:Q9Y5X1] synonym: "SH3 and PX domain-containing protein 3A" EXACT [UniProtKB:Q9Y5X1] xref: EMBL:AAD27832.1 xref: EMBL:AAD43001.1 xref: EMBL:AAF04473.1 xref: EMBL:AAH01084.3 xref: EMBL:AAH05022.1 xref: EMBL:AAL54871.1 xref: EMBL:CAI12979.1 xref: EMBL:CAI15180.1 xref: EMBL:CAI20465.1 xref: UniProtKB:Q9BSI7 xref: UniProtKB:Q9BVM1 xref: UniProtKB:Q9UJH6 xref: UniProtKB:Q9UP20 xref: UniProtKB:Q9Y5X1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005647 ! SNX9_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006486 ! mphosph6-snx9 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:I0017835 ! sos1-snx9-1 physical interaction relationship: participates_in CCO:I0017839 ! sos2-snx9-1 physical interaction relationship: participates_in CCO:I0019218 ! sos2-snx9-2 physical interaction relationship: participates_in CCO:I0019221 ! sos1-snx9-2 physical interaction relationship: transforms_into CCO:B0014151 ! SNX9_HUMAN-Phosphoserine176 [Term] id: CCO:B0005561 name: T4AF1_HUMAN def: "Putative TRAF4-associated factor 1" [UniProtKB:Q9Y448] xref: EMBL:AAD24201.1 xref: EMBL:AAH04543.1 xref: EMBL:AAH14060.1 xref: EMBL:AAH45739.1 xref: EMBL:AAH64344.1 xref: EMBL:AAI07803.1 xref: EMBL:AAI18560.1 xref: EMBL:AAI18640.1 xref: EMBL:AAT66172.1 xref: UniProtKB:Q147U5 xref: UniProtKB:Q32Q57 xref: UniProtKB:Q5ISJ0 xref: UniProtKB:Q6P2S5 xref: UniProtKB:Q6PJM0 xref: UniProtKB:Q86XB4 xref: UniProtKB:Q9Y448 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005718 ! TRAF4AF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006488 ! mphosph6-q9y448 physical interaction [Term] id: CCO:B0005562 name: DLRB1_HUMAN def: "Dynein light chain roadblock-type 1" [UniProtKB:Q9NP97] synonym: "Bithoraxoid-like protein" EXACT [UniProtKB:Q9NP97] synonym: "BLP" EXACT [UniProtKB:Q9NP97] synonym: "Dynein light chain 2A, cytoplasmic" EXACT [UniProtKB:Q9NP97] synonym: "Dynein-associated protein Km23" EXACT [UniProtKB:Q9NP97] xref: EMBL:AAF29126.1 xref: EMBL:AAF86646.1 xref: EMBL:AAH02481.1 xref: EMBL:AAK18712.1 xref: EMBL:AAK95342.1 xref: EMBL:AAL75951.1 xref: EMBL:CAI21456.1 xref: EMBL:CAI23308.1 xref: UniProtKB:Q5TC72 xref: UniProtKB:Q96IV3 xref: UniProtKB:Q9NP97 xref: UniProtKB:Q9NQM2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004482 ! DYNLRB1_human relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000428 ! cytoplasmic dynein complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000995 ! dynein complex relationship: participates_in CCO:I0006489 ! mphosph6-dncl2a physical interaction relationship: participates_in CCO:I0018495 ! bim-dncl2a-1 physical interaction relationship: participates_in CCO:I0018615 ! bclxl-biml-1 physical interaction relationship: transforms_into CCO:B0011543 ! DLRB1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005563 name: RS20_HUMAN def: "40S ribosomal protein S20" [UniProtKB:P60866] xref: EMBL:AAA60286.1 xref: EMBL:AAH07507.1 xref: EMBL:AAH87850.1 xref: EMBL:BAA25820.1 xref: EMBL:BAB79480.1 xref: UniProtKB:P17075 xref: UniProtKB:P60866 xref: UniProtKB:Q5M8S9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005534 ! RPS20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006490 ! mphosph6-rps20 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016511 ! ikbkg-rps20 physical interaction relationship: transforms_into CCO:B0013939 ! RS20_HUMAN-Phosphothreonine9 relationship: transforms_into CCO:B0048382 ! RS20_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005564 name: RHG18_HUMAN def: "Rho GTPase-activating protein 18" [UniProtKB:Q8N392] synonym: "MacGAP" EXACT [UniProtKB:Q8N392] synonym: "Rho-type GTPase-activating protein 18" EXACT [UniProtKB:Q8N392] xref: EMBL:AAH17223.1 xref: EMBL:AAH39611.1 xref: EMBL:AAH62417.1 xref: EMBL:AAI01709.1 xref: EMBL:AAI07417.1 xref: EMBL:AAI11941.1 xref: EMBL:BAB61887.1 xref: EMBL:CAD39167.2 xref: EMBL:CAH72298.1 xref: UniProtKB:Q58EZ3 xref: UniProtKB:Q6P679 xref: UniProtKB:Q6PJD7 xref: UniProtKB:Q8N392 xref: UniProtKB:Q96S64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005482 ! ARHGAP18_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0006493 ! mphosph6-dkfzp762i16 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005565 name: SKIV2_HUMAN def: "Helicase SKI2W" [UniProtKB:Q15477] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q15477] synonym: "Helicase-like protein" EXACT [UniProtKB:Q15477] synonym: "HLP" EXACT [UniProtKB:Q15477] xref: EMBL:AAB52523.1 xref: EMBL:AAB67978.1 xref: EMBL:CAA67024.1 xref: EMBL:CAA88733.1 xref: UniProtKB:O15005 xref: UniProtKB:Q12902 xref: UniProtKB:Q15476 xref: UniProtKB:Q15477 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005621 ! SKIV2L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006494 ! skiv2l-cdc2l2 physical interaction relationship: transforms_into CCO:B0014064 ! SKIV2_HUMAN-Phosphoserine245 relationship: transforms_into CCO:B0014065 ! SKIV2_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0014066 ! SKIV2_HUMAN-Phosphoserine366 [Term] id: CCO:B0005566 name: LSM3_HUMAN def: "U6 snRNA-associated Sm-like protein LSm3" [UniProtKB:P62310] xref: EMBL:AAD56227.1 xref: EMBL:AAG14954.1 xref: EMBL:AAH07055.1 xref: EMBL:CAB45866.1 xref: UniProtKB:P62310 xref: UniProtKB:Q9Y4Z1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004992 ! LSM3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006495 ! lsm3-xpc physical interaction relationship: participates_in CCO:I0015891 ! lsm3-xrn2 physical interaction relationship: participates_in CCO:I0019601 ! lsm3-gdf9 physical interaction relationship: transforms_into CCO:B0012707 ! LSM3_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005567 name: LSM6_HUMAN def: "U6 snRNA-associated Sm-like protein LSm6" [UniProtKB:P62312] xref: EMBL:AAD56230.1 xref: EMBL:AAH16026.1 xref: EMBL:CAB45869.1 xref: UniProtKB:P62312 xref: UniProtKB:Q9Y4Y8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004993 ! LSM6_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: participates_in CCO:I0017323 ! lsm6-pold2 physical interaction [Term] id: CCO:B0005568 name: TR112_HUMAN def: "TRM112-like protein" [UniProtKB:Q9UI30] xref: EMBL:AAF14857.1 xref: EMBL:AAF29116.1 xref: EMBL:AAF82266.1 xref: EMBL:AAH17172.1 xref: EMBL:AAH29482.1 xref: EMBL:AAI05295.1 xref: UniProtKB:Q3MHC7 xref: UniProtKB:Q8N2Z4 xref: UniProtKB:Q9UI30 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005820 ! AD-001_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006499 ! rent1-u315 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: transforms_into CCO:B0071493 ! TR112_HUMAN-Phosphoserine119 [Term] id: CCO:B0005569 name: PKHB2_HUMAN def: "Pleckstrin homology domain-containing family B member 2" [UniProtKB:Q96CS7] synonym: "Evectin-2" EXACT [UniProtKB:Q96CS7] xref: EMBL:AAH01428.1 xref: EMBL:AAH13991.1 xref: EMBL:AAH50695.2 xref: EMBL:BAA91379.1 xref: UniProtKB:Q86W37 xref: UniProtKB:Q96CS7 xref: UniProtKB:Q9BV75 xref: UniProtKB:Q9NWK1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005326 ! PLEKHB2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006500 ! rent1-plekhb2 physical interaction relationship: participates_in CCO:I0008807 ! psmd14-plekhb2 physical interaction [Term] id: CCO:B0005570 name: ACSA_HUMAN def: "Acetyl-coenzyme A synthetase, cytoplasmic" [UniProtKB:Q9NR19] synonym: "AceCS" EXACT [UniProtKB:Q9NR19] synonym: "Acetate--CoA ligase" EXACT [UniProtKB:Q9NR19] synonym: "Acetyl-CoA synthetase" EXACT [UniProtKB:Q9NR19] synonym: "ACS" EXACT [UniProtKB:Q9NR19] synonym: "Acyl-activating enzyme" EXACT [UniProtKB:Q9NR19] synonym: "Acyl-CoA synthetase short-chain family member 2" EXACT [UniProtKB:Q9NR19] synonym: "EC 6.2.1.1" EXACT [UniProtKB:Q9NR19] xref: EMBL:AAF75064.1 xref: EMBL:AAH12172.1 xref: EMBL:CAI19312.1 xref: EMBL:CAI19726.1 xref: UniProtKB:Q5QPH2 xref: UniProtKB:Q96EL0 xref: UniProtKB:Q9NQP7 xref: UniProtKB:Q9NR19 xref: UniProtKB:Q9UJ15 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004018 ! ACSS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006501 ! rent1-acas2 physical interaction relationship: transforms_into CCO:B0010434 ! ACSA_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0010435 ! ACSA_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0010436 ! ACSA_HUMAN-Phosphoserine267 [Term] id: CCO:B0005571 name: BAT5_HUMAN def: "Protein BAT5" [UniProtKB:O95870] synonym: "HLA-B-associated transcript 5" EXACT [UniProtKB:O95870] synonym: "Protein G5" EXACT [UniProtKB:O95870] xref: EMBL:AAD18079.1 xref: EMBL:AAG22475.1 xref: EMBL:AAH31839.1 xref: EMBL:BAA91553.1 xref: EMBL:BAB14455.1 xref: EMBL:BAB63383.1 xref: EMBL:CAI17808.2 xref: EMBL:CAI18401.2 xref: EMBL:CAI18530.1 xref: EMBL:CAM26084.1 xref: EMBL:CAM45793.1 xref: UniProtKB:A2BEY3 xref: UniProtKB:O95870 xref: UniProtKB:Q5SRR1 xref: UniProtKB:Q5SRR2 xref: UniProtKB:Q8WYH0 xref: UniProtKB:Q9NW33 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004141 ! BAT5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0006502 ! rent1-bat5 physical interaction relationship: participates_in CCO:I0007335 ! bat5-ifitm1 physical interaction relationship: participates_in CCO:I0018452 ! bat5-gprc5c physical interaction relationship: participates_in CCO:I0018453 ! bat5-q9ukj0 physical interaction relationship: participates_in CCO:I0018454 ! bat5-safb physical interaction [Term] id: CCO:B0005572 name: GNPTG_HUMAN def: "N-acetylglucosamine-1-phosphotransferase subunit gamma precursor" [UniProtKB:Q9UJJ9] synonym: "GlcNAc-1-phosphotransferase subunit gamma" EXACT [UniProtKB:Q9UJJ9] synonym: "UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma" EXACT [UniProtKB:Q9UJJ9] xref: EMBL:AAG27706.1 xref: EMBL:AAH14592.1 xref: EMBL:AAP34456.1 xref: EMBL:CAB56184.1 xref: UniProtKB:Q6XYD7 xref: UniProtKB:Q96L13 xref: UniProtKB:Q9UJJ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004713 ! GNPTG_human relationship: has_function CCO:F0000463 ! UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006504 ! rent1-c316g12_3 physical interaction [Term] id: CCO:B0005573 name: MED10_HUMAN def: "Mediator of RNA polymerase II transcription subunit 10" [UniProtKB:Q9BTT4] synonym: "Mediator complex subunit 10" EXACT [UniProtKB:Q9BTT4] synonym: "Transformation-related gene 17 protein" EXACT [UniProtKB:Q9BTT4] synonym: "Transformation-related gene 20 protein" EXACT [UniProtKB:Q9BTT4] synonym: "TRG-17" EXACT [UniProtKB:Q9BTT4] synonym: "TRG-20" EXACT [UniProtKB:Q9BTT4] xref: EMBL:AAH03353.1 xref: EMBL:AAQ18038.1 xref: EMBL:AAS47514.1 xref: EMBL:AAT06736.1 xref: EMBL:EAX08110.1 xref: UniProtKB:Q9BTT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005054 ! MED10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0006700 ! cdk8-q9btt4 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0018770 ! med8-nut2-1 physical interaction relationship: participates_in CCO:I0019487 ! med8-q9btt4-1 physical interaction relationship: participates_in CCO:I0020412 ! prei3-mgc5309 physical interaction relationship: participates_in CCO:I0020592 ! mgc5309-jmjd2b physical interaction relationship: participates_in CCO:I0020593 ! mgc5309-pbp physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005574 name: MED29_HUMAN def: "Mediator of RNA polymerase II transcription subunit 29" [UniProtKB:Q9NX70] synonym: "Intersex-like protein" EXACT [UniProtKB:Q9NX70] synonym: "Mediator complex subunit 29" EXACT [UniProtKB:Q9NX70] xref: EMBL:AAH19015.1 xref: EMBL:AAU43732.1 xref: EMBL:BAA91147.1 xref: EMBL:CAB70687.2 xref: UniProtKB:Q5XX09 xref: UniProtKB:Q9NTF4 xref: UniProtKB:Q9NX70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005072 ! MED29_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016031 ! ixl-usp49-3 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0017849 ! tr-crsp6-1 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0018479 ! ixl-usp49-1 physical interaction relationship: participates_in CCO:I0018480 ! ixl-usp49-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005575 name: MED26_HUMAN def: "Mediator of RNA polymerase II transcription subunit 26" [UniProtKB:O95402] synonym: "Activator-recruited cofactor 70 kDa component" EXACT [UniProtKB:O95402] synonym: "ARC70" EXACT [UniProtKB:O95402] synonym: "Cofactor required for Sp1 transcriptional activation subunit 7" EXACT [UniProtKB:O95402] synonym: "CRSP complex subunit 7" EXACT [UniProtKB:O95402] synonym: "Mediator complex subunit 26" EXACT [UniProtKB:O95402] synonym: "Transcriptional coactivator CRSP70" EXACT [UniProtKB:O95402] xref: EMBL:AAD12722.1 xref: EMBL:AAI10431.1 xref: EMBL:AAI27216.1 xref: UniProtKB:A1A4S3 xref: UniProtKB:O95402 xref: UniProtKB:Q0VGB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005069 ! MED26_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0006701 ! crsp7-cdk8-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0012908 ! MED26_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0012909 ! MED26_HUMAN-Phosphoserine447 [Term] id: CCO:B0005576 name: FANCE_HUMAN def: "Fanconi anemia group E protein" [UniProtKB:Q9HB96] synonym: "Protein FACE" EXACT [UniProtKB:Q9HB96] xref: EMBL:AAG16743.1 xref: EMBL:AAH46359.1 xref: EMBL:AAY26395.1 xref: EMBL:CAD92504.1 xref: UniProtKB:Q4ZGH2 xref: UniProtKB:Q9HB96 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004609 ! FANCE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006509 ! fance-fancd2-2 physical interaction relationship: participates_in CCO:I0006611 ! fancd2-fance-1 physical interaction relationship: participates_in CCO:I0007402 ! fance-fanca-1 physical interaction relationship: participates_in CCO:I0007403 ! fance-fanca-2 physical interaction relationship: participates_in CCO:I0007404 ! fance-fancd2-1 physical interaction relationship: transforms_into CCO:B0066118 ! FANCE_HUMAN-Phosphoserine249 [Term] id: CCO:B0005577 name: M3K5_HUMAN def: "Mitogen-activated protein kinase kinase kinase 5" [UniProtKB:Q99683] synonym: "Apoptosis signal-regulating kinase 1" EXACT [UniProtKB:Q99683] synonym: "ASK-1" EXACT [UniProtKB:Q99683] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q99683] synonym: "MAPK/ERK kinase kinase 5" EXACT [UniProtKB:Q99683] synonym: "MEK kinase 5" EXACT [UniProtKB:Q99683] synonym: "MEKK 5" EXACT [UniProtKB:Q99683] xref: EMBL:AAC50894.1 xref: EMBL:AAH54503.1 xref: EMBL:AAH88829.1 xref: EMBL:BAA12684.2 xref: EMBL:CAI15470.1 xref: EMBL:CAI20176.1 xref: UniProtKB:Q5THN3 xref: UniProtKB:Q99461 xref: UniProtKB:Q99683 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005009 ! MAP3K5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006511 ! map3k5-sfn-1 physical interaction relationship: participates_in CCO:I0006512 ! map3k5-ywhaq-1 physical interaction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0006710 ! ask1-daxx physical interaction relationship: participates_in CCO:I0006711 ! ask1-daxx-1 physical interaction relationship: participates_in CCO:I0017354 ! map3k5-ywhaz-1 physical interaction relationship: participates_in CCO:I0017355 ! map3k5-ywhab-1 physical interaction relationship: participates_in CCO:I0017356 ! map3k5-ywhah-1 physical interaction relationship: participates_in CCO:I0017357 ! map3k5-ywhae-1 physical interaction relationship: participates_in CCO:I0017416 ! traf2-ask1 physical interaction relationship: participates_in CCO:I0017497 ! ywhaz-map3k5-1 physical interaction relationship: participates_in CCO:I0017691 ! ask1-ask1 physical interaction relationship: participates_in CCO:I0018245 ! gstp1-jnk1 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: transforms_into CCO:B0012741 ! M3K5_HUMAN-Phosphothreonine838 relationship: transforms_into CCO:B0012742 ! M3K5_HUMAN-Phosphoserine958 relationship: transforms_into CCO:B0012743 ! M3K5_HUMAN-Phosphoserine966 relationship: transforms_into CCO:B0012744 ! M3K5_HUMAN-Phosphoserine1033 relationship: transforms_into CCO:B0041157 ! M3K5_HUMAN-Phosphoserine1029 [Term] id: CCO:B0005578 name: ZN655_HUMAN def: "Zinc finger protein 655" [UniProtKB:Q8N720] synonym: "Vav-interacting Krueppel-like protein" EXACT [UniProtKB:Q8N720] xref: EMBL:AAH11816.1 xref: EMBL:AAH24770.1 xref: EMBL:AAH37407.1 xref: EMBL:AAM33786.1 xref: UniProtKB:Q8IV00 xref: UniProtKB:Q8N720 xref: UniProtKB:Q8TA89 xref: UniProtKB:Q96EZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005966 ! ZNF655_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006525 ! zn655-cdk4-2 physical interaction relationship: participates_in CCO:I0006526 ! zn655-cdk4-3 physical interaction relationship: participates_in CCO:I0007424 ! zn655-cdk4-1 physical interaction relationship: participates_in CCO:I0017374 ! zn655-vav1-4 physical interaction relationship: participates_in CCO:I0017375 ! zn655-vav1-5 physical interaction relationship: participates_in CCO:I0017743 ! zn655-vav1-1 physical interaction relationship: participates_in CCO:I0018320 ! zn655-vav1-2 physical interaction relationship: participates_in CCO:I0018644 ! zn655-vav1-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005579 name: PIAS1_HUMAN def: "E3 SUMO-protein ligase PIAS1" [UniProtKB:O75925] synonym: "DEAD/H box-binding protein 1" EXACT [UniProtKB:O75925] synonym: "GBP" EXACT [UniProtKB:O75925] synonym: "Gu-binding protein" EXACT [UniProtKB:O75925] synonym: "Protein inhibitor of activated STAT protein 1" EXACT [UniProtKB:O75925] synonym: "RNA helicase II-binding protein" EXACT [UniProtKB:O75925] xref: EMBL:AAB58488.1 xref: EMBL:AAC36702.1 xref: EMBL:AAD49722.1 xref: EMBL:AAI18588.1 xref: EMBL:AAI21798.1 xref: UniProtKB:O75925 xref: UniProtKB:Q147X4 xref: UniProtKB:Q99751 xref: UniProtKB:Q9UN02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005310 ! PIAS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006529 ! pias1-p53-1 direct interaction relationship: participates_in CCO:I0006530 ! pias1-p53-2 direct interaction relationship: participates_in CCO:I0006531 ! pias1-p53-3 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013506 ! PIAS1_HUMAN-Phosphoserine466 relationship: transforms_into CCO:B0013507 ! PIAS1_HUMAN-Phosphoserine467 relationship: transforms_into CCO:B0013508 ! PIAS1_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0013509 ! PIAS1_HUMAN-Phosphoserine483 relationship: transforms_into CCO:B0013510 ! PIAS1_HUMAN-Phosphoserine485 relationship: transforms_into CCO:B0013511 ! PIAS1_HUMAN-Phosphothreonine487 [Term] id: CCO:B0005580 name: HS90B_HUMAN def: "Heat shock protein HSP 90-beta" [UniProtKB:P08238] synonym: "HSP 84" EXACT [UniProtKB:P08238] synonym: "HSP 90" EXACT [UniProtKB:P08238] xref: EMBL:AAA36025.1 xref: EMBL:AAA36026.1 xref: EMBL:AAD14062.1 xref: EMBL:AAF82792.1 xref: EMBL:AAH04928.1 xref: EMBL:AAH09206.2 xref: EMBL:AAH12807.1 xref: EMBL:AAH14485.1 xref: EMBL:AAH16753.1 xref: EMBL:AAH68474.1 xref: EMBL:AAQ63401.1 xref: EMBL:ABC40731.1 xref: EMBL:CAB66478.1 xref: EMBL:CAI20095.1 xref: UniProtKB:P08238 xref: UniProtKB:Q5T9W7 xref: UniProtKB:Q9NQW0 xref: UniProtKB:Q9NTK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004831 ! HSP90AB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0006872 ! eif2ak1-cdc37-8 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007800 ! hspcb-chk1-1 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0017207 ! chuk-hspcb physical interaction relationship: participates_in CCO:I0017210 ! ikbkb-hspcb physical interaction relationship: participates_in CCO:I0017214 ! ikbke-hspcb physical interaction relationship: participates_in CCO:I0017218 ! ikbkg-hspcb physical interaction relationship: participates_in CCO:I0017228 ! map3k1-hspcb physical interaction relationship: participates_in CCO:I0017239 ! map3k3-hspcb physical interaction relationship: participates_in CCO:I0017242 ! map3k14-hspcb physical interaction relationship: participates_in CCO:I0017258 ! tbk1-hspcb physical interaction relationship: participates_in CCO:I0017766 ! hspcb-raf1-1 physical interaction relationship: participates_in CCO:I0018863 ! tssk6-hspcb-2 physical interaction relationship: participates_in CCO:I0019509 ! tssk6-hspcb-1 physical interaction relationship: participates_in CCO:I0020287 ! ddx24-hspcb physical interaction relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: transforms_into CCO:B0012268 ! HS90B_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0012269 ! HS90B_HUMAN-Phosphoserine255 relationship: transforms_into CCO:B0012270 ! HS90B_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0012271 ! HS90B_HUMAN-Phosphothreonine297 relationship: transforms_into CCO:B0012272 ! HS90B_HUMAN-Phosphotyrosine484 relationship: transforms_into CCO:B0012273 ! HS90B_HUMAN-N6-acetyllysine624 relationship: transforms_into CCO:B0031333 ! HS90B_HUMAN-Phosphotyrosine305 [Term] id: CCO:B0005581 name: CADH1_HUMAN def: "Epithelial cadherin precursor" [UniProtKB:P12830] synonym: "Cadherin-1" EXACT [UniProtKB:P12830] synonym: "CAM 120/80" EXACT [UniProtKB:P12830] synonym: "CD324 antigen" EXACT [UniProtKB:P12830] synonym: "E-cadherin" EXACT [UniProtKB:P12830] synonym: "Uvomorulin" EXACT [UniProtKB:P12830] xref: EMBL:AAA21764.1 xref: EMBL:AAA61259.1 xref: EMBL:AAD14108.1 xref: EMBL:AAY68225.1 xref: EMBL:BAA08537.1 xref: EMBL:CAA31279.1 xref: EMBL:CAA36522.1 xref: EMBL:CAA78353.1 xref: EMBL:CAA79356.1 xref: EMBL:CAA84586.1 xref: UniProtKB:P12830 xref: UniProtKB:Q13799 xref: UniProtKB:Q14216 xref: UniProtKB:Q15855 xref: UniProtKB:Q16194 xref: UniProtKB:Q4PJ14 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004209 ! CDH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006539 ! cdh1-ctnna1-1 physical interaction relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: transforms_into CCO:B0010889 ! CADH1_HUMAN-Phosphoserine840 relationship: transforms_into CCO:B0010890 ! CADH1_HUMAN-Phosphoserine846 [Term] id: CCO:B0005582 name: CAZA2_HUMAN def: "F-actin-capping protein subunit alpha-2" [UniProtKB:P47755] synonym: "CapZ alpha-2" EXACT [UniProtKB:P47755] xref: EMBL:AAA88848.1 xref: EMBL:AAC00534.1 xref: EMBL:AAC60382.1 xref: EMBL:AAH05338.1 xref: EMBL:AAP35381.1 xref: UniProtKB:P47755 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004226 ! CAPZA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006540 ! apc-ctbb1-1 physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0041285 ! CAZA2_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005583 name: SC23A_HUMAN def: "Protein transport protein Sec23A" [UniProtKB:Q15436] synonym: "SEC23-related protein A" EXACT [UniProtKB:Q15436] xref: EMBL:AAH36649.1 xref: EMBL:CAA65774.1 xref: UniProtKB:Q15436 xref: UniProtKB:Q8NE16 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005569 ! SEC23A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000972 ! COPII vesicle coat relationship: located_in CCO:C0001058 ! smooth endoplasmic reticulum membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0006540 ! apc-ctbb1-1 physical interaction relationship: transforms_into CCO:B0070340 ! SC23A_HUMAN-Phosphothreonine308 [Term] id: CCO:B0005584 name: DDB1_HUMAN def: "DNA damage-binding protein 1" [UniProtKB:Q16531] synonym: "Damage-specific DNA-binding protein 1" EXACT [UniProtKB:Q16531] synonym: "DDB p127 subunit" EXACT [UniProtKB:Q16531] synonym: "DDBa" EXACT [UniProtKB:Q16531] synonym: "DNA damage-binding protein a" EXACT [UniProtKB:Q16531] synonym: "HBV X-associated protein 1" EXACT [UniProtKB:Q16531] synonym: "UV-damaged DNA-binding factor" EXACT [UniProtKB:Q16531] synonym: "UV-damaged DNA-binding protein 1" EXACT [UniProtKB:Q16531] synonym: "UV-DDB 1" EXACT [UniProtKB:Q16531] synonym: "XAP-1" EXACT [UniProtKB:Q16531] synonym: "Xeroderma pigmentosum group E-complementing protein" EXACT [UniProtKB:Q16531] synonym: "XPCe" EXACT [UniProtKB:Q16531] synonym: "XPE-BF" EXACT [UniProtKB:Q16531] synonym: "XPE-binding factor" EXACT [UniProtKB:Q16531] xref: EMBL:AAA62838.1 xref: EMBL:AAA88883.1 xref: EMBL:AAC50349.1 xref: EMBL:AAH11686.1 xref: EMBL:AAH50530.1 xref: EMBL:AAH51764.1 xref: EMBL:AAX44048.1 xref: EMBL:CAA05770.1 xref: EMBL:EAW73935.1 xref: UniProtKB:A6NG77 xref: UniProtKB:O15176 xref: UniProtKB:Q13289 xref: UniProtKB:Q16531 xref: UniProtKB:Q58F96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004450 ! DDB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006540 ! apc-ctbb1-1 physical interaction relationship: participates_in CCO:I0006808 ! cul4b-ddb1-2 physical interaction relationship: participates_in CCO:I0006809 ! cul4b-tle2 physical interaction relationship: participates_in CCO:I0006810 ! ddb1-ddb2-1 physical interaction relationship: participates_in CCO:I0006812 ! cul4a-cul4b physical interaction relationship: participates_in CCO:I0006813 ! cul4a-eed physical interaction relationship: participates_in CCO:I0006814 ! cul4a-cul4b-1 physical interaction relationship: participates_in CCO:I0006817 ! l2dtl-cul4b physical interaction relationship: participates_in CCO:I0006818 ! tle2-ddb1-1 physical interaction relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0007514 ! h3_peptide-cul4a physical interaction relationship: participates_in CCO:I0008518 ! ikbkg-ddb1 physical interaction relationship: participates_in CCO:I0008519 ! map3k1-ddb1 physical interaction relationship: participates_in CCO:I0008520 ! map3k3-ddb1 physical interaction relationship: participates_in CCO:I0008521 ! tnfrsf1b-ddb1 physical interaction relationship: participates_in CCO:I0008522 ! tle2-ddb1 physical interaction relationship: participates_in CCO:I0008523 ! ddb1-ddb2 physical interaction relationship: participates_in CCO:I0008524 ! rbbp5-wdr5-1 physical interaction relationship: participates_in CCO:I0008525 ! l2dt1-ddb1 physical interaction relationship: participates_in CCO:I0008526 ! eed-ddb1 physical interaction relationship: participates_in CCO:I0008527 ! ddb1-brap physical interaction relationship: participates_in CCO:I0008528 ! ddb1-cops3 physical interaction relationship: participates_in CCO:I0008529 ! cop1-ddb1 physical interaction relationship: participates_in CCO:I0008530 ! l2dtl-ddb1 physical interaction relationship: participates_in CCO:I0008531 ! wdr57-ddb1 physical interaction relationship: participates_in CCO:I0008532 ! wdr26-ddb1 physical interaction relationship: participates_in CCO:I0008533 ! wdr5b-ddb1 physical interaction relationship: participates_in CCO:I0008534 ! wdr5-ddb1 physical interaction relationship: participates_in CCO:I0008535 ! vamp3-ddb1 physical interaction relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: transforms_into CCO:B0011454 ! DDB1_HUMAN-Phosphothreonine8 relationship: transforms_into CCO:B0011455 ! DDB1_HUMAN-Phosphoserine757 relationship: transforms_into CCO:B0011456 ! DDB1_HUMAN-Phosphoserine766 [Term] id: CCO:B0005585 name: TIF1B_HUMAN def: "Transcription intermediary factor 1-beta" [UniProtKB:Q13263] synonym: "KAP-1" EXACT [UniProtKB:Q13263] synonym: "KRAB-associated protein 1" EXACT [UniProtKB:Q13263] synonym: "KRAB-interacting protein 1" EXACT [UniProtKB:Q13263] synonym: "KRIP-1" EXACT [UniProtKB:Q13263] synonym: "Nuclear corepressor KAP-1" EXACT [UniProtKB:Q13263] synonym: "RING finger protein 96" EXACT [UniProtKB:Q13263] synonym: "TIF1-beta" EXACT [UniProtKB:Q13263] synonym: "Tripartite motif-containing protein 28" EXACT [UniProtKB:Q13263] xref: EMBL:AAA74954.1 xref: EMBL:AAB37341.1 xref: EMBL:AAB51517.1 xref: EMBL:AAH04978.1 xref: EMBL:AAH07390.2 xref: EMBL:AAH52986.1 xref: EMBL:CAA66150.1 xref: UniProtKB:O00677 xref: UniProtKB:Q13263 xref: UniProtKB:Q7Z632 xref: UniProtKB:Q93040 xref: UniProtKB:Q96IM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005781 ! TRIM28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006540 ! apc-ctbb1-1 physical interaction relationship: participates_in CCO:I0016509 ! ikbkg-trim28 physical interaction relationship: participates_in CCO:I0017899 ! cbx5-trim28-2 physical interaction relationship: participates_in CCO:I0017900 ! cbx5-trim28-3 physical interaction relationship: participates_in CCO:I0018853 ! cbx3-trim28-2 physical interaction relationship: participates_in CCO:I0018854 ! cbx5-trim28-1 physical interaction relationship: participates_in CCO:I0019868 ! trim28-chd3 physical interaction relationship: participates_in CCO:I0020208 ! trim28-spg7 physical interaction relationship: participates_in CCO:I0020209 ! trim28-vim physical interaction relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: transforms_into CCO:B0014362 ! TIF1B_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0014363 ! TIF1B_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0014364 ! TIF1B_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0014365 ! TIF1B_HUMAN-Phosphoserine440 relationship: transforms_into CCO:B0014366 ! TIF1B_HUMAN-Phosphoserine466 relationship: transforms_into CCO:B0014367 ! TIF1B_HUMAN-Phosphoserine471 relationship: transforms_into CCO:B0014368 ! TIF1B_HUMAN-Phosphoserine473 relationship: transforms_into CCO:B0014369 ! TIF1B_HUMAN-Phosphoserine501 relationship: transforms_into CCO:B0014370 ! TIF1B_HUMAN-Phosphothreonine541 relationship: transforms_into CCO:B0014371 ! TIF1B_HUMAN-Phosphoserine594 relationship: transforms_into CCO:B0014372 ! TIF1B_HUMAN-Phosphoserine681 relationship: transforms_into CCO:B0014373 ! TIF1B_HUMAN-Phosphoserine683 relationship: transforms_into CCO:B0014374 ! TIF1B_HUMAN-Phosphoserine757 relationship: transforms_into CCO:B0014375 ! TIF1B_HUMAN-Phosphoserine824 relationship: transforms_into CCO:B0048410 ! TIF1B_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0048411 ! TIF1B_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0071402 ! TIF1B_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0071403 ! TIF1B_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0071404 ! TIF1B_HUMAN-Phosphoserine752 [Term] id: CCO:B0005586 name: DSS1_HUMAN def: "26S proteasome complex subunit DSS1" [UniProtKB:P60896] synonym: "Deleted in split hand/split foot protein 1" EXACT [UniProtKB:P60896] synonym: "Split hand/foot deleted protein 1" EXACT [UniProtKB:P60896] synonym: "Split hand/foot malformation type 1 protein" EXACT [UniProtKB:P60896] xref: EMBL:AAA91179.1 xref: EMBL:AAH32782.1 xref: EMBL:AAQ93368.1 xref: UniProtKB:P60896 xref: UniProtKB:Q13437 xref: UniProtKB:Q61067 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004514 ! SHFM1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001385 ! integrator complex relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0006543 ! brca2-shfdg1-2 physical interaction relationship: participates_in CCO:I0006670 ! brca2-shfdg1-3 physical interaction relationship: participates_in CCO:I0006671 ! shfdg1-brca2-3 physical interaction relationship: participates_in CCO:I0007133 ! brca2-shfdg1-1 physical interaction [Term] id: CCO:B0005587 name: TOP1_HUMAN def: "DNA topoisomerase 1" [UniProtKB:P11387] synonym: "DNA topoisomerase I" EXACT [UniProtKB:P11387] synonym: "EC 5.99.1.2" EXACT [UniProtKB:P11387] xref: EMBL:AAA61206.1 xref: EMBL:AAA61207.1 xref: EMBL:AAA61208.1 xref: EMBL:AAB60379.1 xref: EMBL:AAB60380.1 xref: EMBL:CAA34500.2 xref: EMBL:CAA36834.1 xref: EMBL:CAI19767.1 xref: EMBL:CAI42886.1 xref: UniProtKB:O43256 xref: UniProtKB:P11387 xref: UniProtKB:Q12855 xref: UniProtKB:Q12856 xref: UniProtKB:Q15610 xref: UniProtKB:Q5TFY3 xref: UniProtKB:Q9UJN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005810 ! TOP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000419 ! DNA topoisomerase activity relationship: has_function CCO:F0000420 ! DNA topoisomerase type I activity relationship: has_function CCO:F0000421 ! DNA topoisomerase (ATP-hydrolyzing) activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:P0000632 ! DNA unwinding during replication [Term] id: CCO:B0005588 name: AKAP9_HUMAN def: "A-kinase anchor protein 9" [UniProtKB:Q99996] synonym: "A-kinase anchor protein 350 kDa" EXACT [UniProtKB:Q99996] synonym: "A-kinase anchor protein 450 kDa" EXACT [UniProtKB:Q99996] synonym: "AKAP 120-like protein" EXACT [UniProtKB:Q99996] synonym: "AKAP 350" EXACT [UniProtKB:Q99996] synonym: "AKAP 450" EXACT [UniProtKB:Q99996] synonym: "Centrosome- and Golgi-localized PKN-associated protein" EXACT [UniProtKB:Q99996] synonym: "CG-NAP" EXACT [UniProtKB:Q99996] synonym: "hgAKAP 350" EXACT [UniProtKB:Q99996] synonym: "PRKA9" EXACT [UniProtKB:Q99996] synonym: "Protein hyperion" EXACT [UniProtKB:Q99996] synonym: "Protein kinase A-anchoring protein 9" EXACT [UniProtKB:Q99996] synonym: "Protein yotiao" EXACT [UniProtKB:Q99996] xref: EMBL:AAB86384.1 xref: EMBL:AAB96867.2 xref: EMBL:AAC60380.1 xref: EMBL:AAD22767.1 xref: EMBL:AAD39719.1 xref: EMBL:AAS07419.1 xref: EMBL:BAA34523.1 xref: EMBL:BAA78718.1 xref: EMBL:CAA09361.1 xref: EMBL:CAB40713.1 xref: UniProtKB:O14869 xref: UniProtKB:O43355 xref: UniProtKB:O94895 xref: UniProtKB:Q75N20 xref: UniProtKB:Q99996 xref: UniProtKB:Q9UQH3 xref: UniProtKB:Q9UQQ4 xref: UniProtKB:Q9Y6B8 xref: UniProtKB:Q9Y6Y2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004043 ! AKAP9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006568 ! cdc5l-akap9 physical interaction relationship: participates_in CCO:I0017421 ! disc1-akap9 physical interaction relationship: participates_in CCO:I0017422 ! tnik-akap9 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010486 ! AKAP9_HUMAN-Phosphoserine3869 [Term] id: CCO:B0005589 name: LSD1_HUMAN def: "Lysine-specific histone demethylase 1" [UniProtKB:O60341] synonym: "BRAF35-HDAC complex protein BHC110" EXACT [UniProtKB:O60341] synonym: "EC 1.-.-.-" EXACT [UniProtKB:O60341] synonym: "Flavin-containing amine oxidase domain-containing protein 2" EXACT [UniProtKB:O60341] xref: EMBL:AAH16639.1 xref: EMBL:AAH25362.1 xref: EMBL:AAH40194.3 xref: EMBL:AAH48134.2 xref: EMBL:BAA25527.1 xref: EMBL:CAD38675.2 xref: EMBL:CAI19707.2 xref: EMBL:CAI19708.2 xref: UniProtKB:O60341 xref: UniProtKB:Q5TH94 xref: UniProtKB:Q5TH95 xref: UniProtKB:Q86VT7 xref: UniProtKB:Q8IXK4 xref: UniProtKB:Q8NDP6 xref: UniProtKB:Q8TAZ3 xref: UniProtKB:Q96AW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004990 ! AOF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006569 ! cdc5l-aof2 physical interaction relationship: participates_in CCO:I0019402 ! aof2-immt-1 physical interaction relationship: participates_in CCO:I0019648 ! aof2-gdf9 physical interaction relationship: participates_in CCO:I0019659 ! ascc2-aof2 physical interaction relationship: participates_in CCO:I0019893 ! aof2-setdb1 physical interaction relationship: participates_in CCO:I0019917 ! atp5j2-aof2 physical interaction relationship: participates_in CCO:I0020226 ! aof2-immt physical interaction relationship: participates_in CCO:I0020227 ! aof2-unc119 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012706 ! LSD1_HUMAN-Phosphoserine166 [Term] id: CCO:B0005590 name: CEP63_HUMAN def: "Centrosomal protein of 63 kDa" [UniProtKB:Q96MT8] synonym: "Cep63" EXACT [UniProtKB:Q96MT8] xref: EMBL:AAH14050.1 xref: EMBL:AAH68997.1 xref: EMBL:BAB14578.1 xref: EMBL:BAB14662.1 xref: EMBL:BAB71192.1 xref: EMBL:DAA05503.1 xref: UniProtKB:Q96CR0 xref: UniProtKB:Q96MT8 xref: UniProtKB:Q9H8F5 xref: UniProtKB:Q9H8N0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004330 ! CEP63_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:I0006578 ! cep63-cspg6 physical interaction relationship: participates_in CCO:I0015026 ! cep63-mbip physical interaction relationship: participates_in CCO:I0017425 ! cep63-camkk2 physical interaction relationship: participates_in CCO:I0017449 ! cep63-snrp70 physical interaction relationship: participates_in CCO:I0017455 ! cep63-sptan1 physical interaction relationship: participates_in CCO:I0017460 ! cep63-sptbn1 physical interaction [Term] id: CCO:B0005591 name: DISC1_HUMAN def: "Disrupted in schizophrenia 1 protein" [UniProtKB:Q9NRI5] xref: EMBL:AAF73874.1 xref: EMBL:AAF73877.1 xref: EMBL:AAF73889.1 xref: EMBL:BAA32302.1 xref: EMBL:CAD44628.1 xref: EMBL:CAD44631.1 xref: EMBL:CAH70955.1 xref: EMBL:CAH70956.1 xref: EMBL:CAH70957.1 xref: EMBL:CAI15677.1 xref: EMBL:CAI15679.1 xref: EMBL:CAI17204.1 xref: EMBL:CAI17206.1 xref: EMBL:CAI17207.1 xref: EMBL:CAI21886.1 xref: EMBL:CAI21888.1 xref: EMBL:CAI22543.1 xref: EMBL:CAI23013.1 xref: UniProtKB:O75045 xref: UniProtKB:Q5VT44 xref: UniProtKB:Q5VT45 xref: UniProtKB:Q8IXJ0 xref: UniProtKB:Q8IXJ1 xref: UniProtKB:Q9BX19 xref: UniProtKB:Q9NRI3 xref: UniProtKB:Q9NRI4 xref: UniProtKB:Q9NRI5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004474 ! DISC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0006572 ! disc1-cdc5l physical interaction relationship: participates_in CCO:I0006573 ! disc1-cdc5l-1 physical interaction relationship: participates_in CCO:I0006575 ! disc1-cdk5rap3-1 physical interaction relationship: participates_in CCO:I0006576 ! disc1-cdk5rap3-2 physical interaction relationship: participates_in CCO:I0006579 ! disc1-dnch1 physical interaction relationship: participates_in CCO:I0006580 ! disc1-dnch1-2 physical interaction relationship: participates_in CCO:I0006589 ! disc1-macf1 physical interaction relationship: participates_in CCO:I0006590 ! disc1-macf1-2 physical interaction relationship: participates_in CCO:I0006591 ! disc1-macf1-3 physical interaction relationship: participates_in CCO:I0006592 ! disc1-macf1-4 physical interaction relationship: participates_in CCO:I0006596 ! disc1-pafah1b1 physical interaction relationship: participates_in CCO:I0006597 ! disc1-pafah1b1-1 physical interaction relationship: participates_in CCO:I0006601 ! disc1-rad21 physical interaction relationship: participates_in CCO:I0006602 ! disc1-smc2l1 physical interaction relationship: participates_in CCO:I0006604 ! disc1-tubb2-1 physical interaction relationship: participates_in CCO:I0006722 ! disc1-atf5-6 colocalization relationship: participates_in CCO:I0006723 ! disc1-tubg colocalization relationship: participates_in CCO:I0006799 ! disc1-cdk5rap3 physical interaction relationship: participates_in CCO:I0006800 ! disc1-dctn1 physical interaction relationship: participates_in CCO:I0006801 ! disc1-dnch1-1 physical interaction relationship: participates_in CCO:I0006802 ! disc1-macf1-1 physical interaction relationship: participates_in CCO:I0006803 ! disc1-ppp5c physical interaction relationship: participates_in CCO:I0006804 ! disc1-ywhaq physical interaction relationship: participates_in CCO:I0006889 ! disc1-atf5-3 physical interaction relationship: participates_in CCO:I0006997 ! disc1-atf5 physical interaction relationship: participates_in CCO:I0006998 ! disc1-atf5-5 physical interaction relationship: participates_in CCO:I0007293 ! disc1-atf5-1 physical interaction relationship: participates_in CCO:I0007371 ! disc1-atf5-4 physical interaction relationship: participates_in CCO:I0007420 ! disc1-atf5-2 physical interaction relationship: participates_in CCO:I0007789 ! disc1-atf5-7 physical interaction relationship: participates_in CCO:I0007970 ! disc1-tubg-1 physical interaction relationship: participates_in CCO:I0017421 ! disc1-akap9 physical interaction relationship: participates_in CCO:I0017427 ! disc1-dpysl2 physical interaction relationship: participates_in CCO:I0017428 ! disc1-dpysl3 physical interaction relationship: participates_in CCO:I0017429 ! disc1-eif3s3-6 physical interaction relationship: participates_in CCO:I0017430 ! disc1-eif3s3-7 physical interaction relationship: participates_in CCO:I0017431 ! disc1-gnb1 physical interaction relationship: participates_in CCO:I0017433 ! disc1-hapip physical interaction relationship: participates_in CCO:I0017435 ! disc1-kiaa0826 physical interaction relationship: participates_in CCO:I0017436 ! disc1-kiaa0826-1 physical interaction relationship: participates_in CCO:I0017438 ! disc1-kifap3 physical interaction relationship: participates_in CCO:I0017439 ! disc1-myt1l physical interaction relationship: participates_in CCO:I0017443 ! disc1-ppp4r1 physical interaction relationship: participates_in CCO:I0017445 ! disc1-sh3bp5 physical interaction relationship: participates_in CCO:I0017446 ! disc1-sh3bp5-1 physical interaction relationship: participates_in CCO:I0017448 ! disc1-smarce1-1 physical interaction relationship: participates_in CCO:I0017450 ! disc1-snx6-1 physical interaction relationship: participates_in CCO:I0017453 ! disc1-sptan1 physical interaction relationship: participates_in CCO:I0017454 ! disc1-sptan1-1 physical interaction relationship: participates_in CCO:I0017457 ! disc1-sptbn1 physical interaction relationship: participates_in CCO:I0017458 ! disc1-sptbn1-1 physical interaction relationship: participates_in CCO:I0017459 ! disc1-sptbn1-2 physical interaction relationship: participates_in CCO:I0017462 ! disc1-srgap2 physical interaction relationship: participates_in CCO:I0017464 ! disc1-tnik physical interaction relationship: participates_in CCO:I0017465 ! disc1-tnik-1 physical interaction relationship: participates_in CCO:I0017466 ! disc1-tnks physical interaction relationship: participates_in CCO:I0017469 ! disc1-trio physical interaction relationship: participates_in CCO:I0017470 ! disc1-trio-1 physical interaction relationship: participates_in CCO:I0017471 ! disc1-trio-2 physical interaction relationship: participates_in CCO:I0017473 ! disc1-tubb2 physical interaction relationship: participates_in CCO:I0017474 ! disc1-xrn2 physical interaction relationship: participates_in CCO:I0017475 ! disc1-ywhae physical interaction relationship: participates_in CCO:I0017476 ! disc1-ywhae-1 physical interaction relationship: participates_in CCO:I0017477 ! disc1-ywhaz-1 physical interaction relationship: participates_in CCO:I0017480 ! disc1-znf197 physical interaction relationship: participates_in CCO:I0017817 ! disc1-eif3s3-5 physical interaction relationship: participates_in CCO:I0017818 ! disc1-pde4b physical interaction relationship: participates_in CCO:I0017819 ! disc1-smarce1 physical interaction relationship: participates_in CCO:I0017820 ! disc1-snx6 physical interaction relationship: participates_in CCO:I0017821 ! disc1-ywhaz physical interaction relationship: participates_in CCO:I0017914 ! disc1-itsn1-2 physical interaction relationship: participates_in CCO:I0018086 ! disc1-eif3s3 physical interaction relationship: participates_in CCO:I0018087 ! disc1-itsn1 physical interaction relationship: participates_in CCO:I0018088 ! disc1-eif3s3-4 physical interaction relationship: participates_in CCO:I0018089 ! disc1-spectrin-2 physical interaction relationship: participates_in CCO:I0018366 ! disc1-atf4-1 physical interaction relationship: participates_in CCO:I0018367 ! disc1-eif3s3-2 physical interaction relationship: participates_in CCO:I0018368 ! disc1-rassf7-1 physical interaction relationship: participates_in CCO:I0018369 ! disc1-itsn1-1 physical interaction relationship: participates_in CCO:I0018370 ! disc1-spectrin-1 physical interaction relationship: participates_in CCO:I0018543 ! disc1-eif3s3-1 physical interaction relationship: participates_in CCO:I0018544 ! disc1-atf4 physical interaction relationship: participates_in CCO:I0018545 ! disc1-rassf7 physical interaction relationship: participates_in CCO:I0018546 ! disc1-spectrin physical interaction relationship: participates_in CCO:I0018642 ! disc1-eif3s3-3 physical interaction relationship: participates_in CCO:I0019295 ! disc1-atf4-2 physical interaction [Term] id: CCO:B0005592 name: EXOC1_HUMAN def: "Exocyst complex component 1" [UniProtKB:Q9NV70] synonym: "Exocyst complex component Sec3" EXACT [UniProtKB:Q9NV70] xref: EMBL:AAF64268.1 xref: EMBL:AAH20650.1 xref: EMBL:AAH94751.1 xref: EMBL:BAA91886.1 xref: EMBL:BAB55095.1 xref: UniProtKB:Q504V4 xref: UniProtKB:Q8WUE7 xref: UniProtKB:Q96T15 xref: UniProtKB:Q9NV70 xref: UniProtKB:Q9NZE4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004595 ! EXOC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006574 ! exoc1-nuf2 physical interaction relationship: participates_in CCO:I0006594 ! exoc1-macf1 physical interaction relationship: participates_in CCO:I0017447 ! exoc1-sh3bp5 physical interaction relationship: participates_in CCO:I0017456 ! exoc1-sptan1 physical interaction relationship: participates_in CCO:I0017472 ! exoc1-trio physical interaction relationship: transforms_into CCO:B0065181 ! EXOC1_HUMAN-Phosphoserine470 relationship: transforms_into CCO:B0065182 ! EXOC1_HUMAN-Phosphoserine473 [Term] id: CCO:B0005593 name: CRNL1_HUMAN def: "Crooked neck-like protein 1" [UniProtKB:Q9BZJ0] synonym: "Crooked neck homolog" EXACT [UniProtKB:Q9BZJ0] synonym: "hCrn" EXACT [UniProtKB:Q9BZJ0] xref: EMBL:AAF65571.2 xref: EMBL:AAK01924.1 xref: EMBL:AAK01925.1 xref: EMBL:AAK01926.1 xref: EMBL:AAK01927.1 xref: EMBL:AAL39004.1 xref: EMBL:BAB14303.1 xref: EMBL:BAB14485.1 xref: EMBL:BAB14659.1 xref: EMBL:CAI42113.1 xref: UniProtKB:Q5JY64 xref: UniProtKB:Q8WYI5 xref: UniProtKB:Q9BZI9 xref: UniProtKB:Q9BZJ0 xref: UniProtKB:Q9BZJ1 xref: UniProtKB:Q9BZJ2 xref: UniProtKB:Q9GZW7 xref: UniProtKB:Q9H8F8 xref: UniProtKB:Q9NQH5 xref: UniProtKB:Q9NYD8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004398 ! CRNKL1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0006577 ! cdc5l-crnkl1 physical interaction [Term] id: CCO:B0005594 name: HOOK1_HUMAN def: "Protein Hook homolog 1" [UniProtKB:Q9UJC3] synonym: "h-hook1" EXACT [UniProtKB:Q9UJC3] synonym: "hHK1" EXACT [UniProtKB:Q9UJC3] xref: EMBL:AAC09298.1 xref: EMBL:AAH11621.1 xref: EMBL:CAI22779.1 xref: UniProtKB:O60561 xref: UniProtKB:Q5TG44 xref: UniProtKB:Q9UJC3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004823 ! HOOK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006582 ! cdc5l-hook1 physical interaction relationship: participates_in CCO:I0015270 ! hook1-znf250 physical interaction relationship: transforms_into CCO:B0012253 ! HOOK1_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0012254 ! HOOK1_HUMAN-Phosphothreonine699 [Term] id: CCO:B0005595 name: GSE1_HUMAN def: "Genetic suppressor element 1" [UniProtKB:Q14687] xref: EMBL:AAH00753.2 xref: EMBL:AAH09854.2 xref: EMBL:AAH37556.1 xref: EMBL:BAA11499.1 xref: UniProtKB:Q14687 xref: UniProtKB:Q8IY61 xref: UniProtKB:Q96GA4 xref: UniProtKB:Q9BW09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004734 ! GSE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006583 ! cdc5l-kiaa0182 physical interaction relationship: participates_in CCO:I0020051 ! kiaa0182-g22p1 physical interaction relationship: transforms_into CCO:B0066634 ! GSE1_HUMAN-Phosphoserine826 relationship: transforms_into CCO:B0066635 ! GSE1_HUMAN-Phosphoserine828 relationship: transforms_into CCO:B0066636 ! GSE1_HUMAN-Phosphoserine909 relationship: transforms_into CCO:B0066637 ! GSE1_HUMAN-Phosphoserine1101 [Term] id: CCO:B0005596 name: K0240_HUMAN def: "Uncharacterized protein KIAA0240" [UniProtKB:Q6AI39] xref: EMBL:BAA13246.2 xref: EMBL:CAH10475.1 xref: EMBL:CAI14820.2 xref: EMBL:CAI21488.2 xref: UniProtKB:Q5TFZ3 xref: UniProtKB:Q6AI39 xref: UniProtKB:Q92514 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004915 ! KIAA0240_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006584 ! cdc5l-kiaa0240 physical interaction [Term] id: CCO:B0005597 name: Q5VVE9_HUMAN def: "Zinc finger protein 451" [UniProtKB:Q5VVE9] xref: EMBL:CAH71222.1 xref: UniProtKB:Q5VVE9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005961 ! ZNF451_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006585 ! cdc5l-znf451 physical interaction [Term] id: CCO:B0005598 name: KIF3C_HUMAN def: "Kinesin-like protein KIF3C" [UniProtKB:O14782] xref: EMBL:AAC05302.1 xref: EMBL:AAC39562.1 xref: EMBL:AAH92406.1 xref: EMBL:AAI30424.1 xref: EMBL:CAA05252.1 xref: EMBL:CAA05253.1 xref: EMBL:CAA05254.1 xref: EMBL:CAA05255.1 xref: EMBL:CAA05256.1 xref: EMBL:CAA05257.1 xref: EMBL:CAA05258.1 xref: UniProtKB:O14782 xref: UniProtKB:O43544 xref: UniProtKB:Q562F7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004949 ! KIF3C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006586 ! cdc5l-kif3c physical interaction relationship: transforms_into CCO:B0012608 ! KIF3C_HUMAN-Phosphothreonine585 [Term] id: CCO:B0005599 name: KINH_HUMAN def: "Kinesin-1 heavy chain" [UniProtKB:P33176] synonym: "Conventional kinesin heavy chain" EXACT [UniProtKB:P33176] synonym: "Ubiquitous kinesin heavy chain" EXACT [UniProtKB:P33176] synonym: "UKHC" EXACT [UniProtKB:P33176] xref: EMBL:AAI26280.1 xref: EMBL:AAI26282.1 xref: EMBL:CAA46703.1 xref: EMBL:CAH71618.1 xref: UniProtKB:A0AVB2 xref: UniProtKB:P33176 xref: UniProtKB:Q5VZ85 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004952 ! KIF5B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0001625 ! ciliary rootlet relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0006587 ! cdc5l-kif5b physical interaction relationship: participates_in CCO:I0016512 ! ikbkg-kif5b physical interaction [Term] id: CCO:B0005600 name: K1267_HUMAN def: "Uncharacterized protein KIAA1267" [UniProtKB:Q7Z3B3] xref: EMBL:AAH06271.1 xref: EMBL:AAH35892.1 xref: EMBL:AAH98376.1 xref: EMBL:BAA86581.1 xref: EMBL:CAB55949.1 xref: EMBL:CAB70694.1 xref: EMBL:CAD97958.1 xref: EMBL:CAH10565.1 xref: UniProtKB:Q6AW85 xref: UniProtKB:Q7Z3B3 xref: UniProtKB:Q8IYH1 xref: UniProtKB:Q9BRH0 xref: UniProtKB:Q9NTE7 xref: UniProtKB:Q9UFT0 xref: UniProtKB:Q9ULF3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004916 ! KIAA1267_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006588 ! cdc5l-kiaa1267 physical interaction relationship: transforms_into CCO:B0012453 ! K1267_HUMAN-Phosphoserine1082 relationship: transforms_into CCO:B0048300 ! K1267_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0048301 ! K1267_HUMAN-Phosphoserine991 relationship: transforms_into CCO:B0048302 ! K1267_HUMAN-Phosphothreonine1003 relationship: transforms_into CCO:B0048303 ! K1267_HUMAN-Phosphoserine1045 relationship: transforms_into CCO:B0067235 ! K1267_HUMAN-Phosphoserine249 [Term] id: CCO:B0005601 name: MYT1L_HUMAN def: "Myelin transcription factor 1-like protein" [UniProtKB:Q9UL68] synonym: "MyT1-L" EXACT [UniProtKB:Q9UL68] synonym: "MyT1L protein" EXACT [UniProtKB:Q9UL68] xref: EMBL:AAF14051.1 xref: EMBL:AAH71612.1 xref: EMBL:BAA83058.2 xref: UniProtKB:Q6IQ17 xref: UniProtKB:Q9UL68 xref: UniProtKB:Q9UPP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005152 ! MYT1L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006595 ! cdc5l-myt1l physical interaction relationship: participates_in CCO:I0017439 ! disc1-myt1l physical interaction relationship: participates_in CCO:I0017440 ! tnik-myt1l physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005602 name: LIPA2_HUMAN def: "Liprin-alpha-2" [UniProtKB:O75334] synonym: "Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2" EXACT [UniProtKB:O75334] synonym: "PTPRF-interacting protein alpha-2" EXACT [UniProtKB:O75334] xref: EMBL:AAC26100.1 xref: UniProtKB:O75334 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004982 ! PPFIA2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000880 ! synaptosome relationship: participates_in CCO:I0006598 ! cdc5l-ppfia2 physical interaction relationship: transforms_into CCO:B0012702 ! LIPA2_HUMAN-Phosphoserine538 relationship: transforms_into CCO:B0012703 ! LIPA2_HUMAN-Phosphoserine689 relationship: transforms_into CCO:B0012704 ! LIPA2_HUMAN-Phosphoserine774 [Term] id: CCO:B0005603 name: TNIK_HUMAN def: "TRAF2 and NCK-interacting protein kinase" [UniProtKB:Q9UKE5] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UKE5] xref: EMBL:AAF03782.1 xref: EMBL:AAF03783.1 xref: EMBL:AAF03784.1 xref: EMBL:AAF03785.1 xref: EMBL:AAF03786.1 xref: EMBL:AAF03787.1 xref: EMBL:AAF03788.1 xref: EMBL:AAF03789.1 xref: EMBL:AAH19081.2 xref: EMBL:BAA25477.2 xref: UniProtKB:O60298 xref: UniProtKB:Q8WUY7 xref: UniProtKB:Q9UKD8 xref: UniProtKB:Q9UKD9 xref: UniProtKB:Q9UKE0 xref: UniProtKB:Q9UKE1 xref: UniProtKB:Q9UKE2 xref: UniProtKB:Q9UKE3 xref: UniProtKB:Q9UKE4 xref: UniProtKB:Q9UKE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005800 ! TNIK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006600 ! tnik-ppp1r13b physical interaction relationship: participates_in CCO:I0017422 ! tnik-akap9 physical interaction relationship: participates_in CCO:I0017423 ! tnik-ank2 physical interaction relationship: participates_in CCO:I0017426 ! tnik-cnksr2 physical interaction relationship: participates_in CCO:I0017432 ! tnik-hars physical interaction relationship: participates_in CCO:I0017437 ! tnik-kibra physical interaction relationship: participates_in CCO:I0017440 ! tnik-myt1l physical interaction relationship: participates_in CCO:I0017441 ! tnik-ncor2 physical interaction relationship: participates_in CCO:I0017442 ! tnik-nef3 physical interaction relationship: participates_in CCO:I0017461 ! tnik-sptbn1 physical interaction relationship: participates_in CCO:I0017463 ! tnik-srgap3 physical interaction relationship: participates_in CCO:I0017464 ! disc1-tnik physical interaction relationship: participates_in CCO:I0017465 ! disc1-tnik-1 physical interaction relationship: participates_in CCO:I0017468 ! tnik-trim2 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0014421 ! TNIK_HUMAN-Phosphoserine680 relationship: transforms_into CCO:B0014422 ! TNIK_HUMAN-Phosphoserine764 relationship: transforms_into CCO:B0014423 ! TNIK_HUMAN-Phosphoserine769 relationship: transforms_into CCO:B0014424 ! TNIK_HUMAN-Phosphothreonine987 relationship: transforms_into CCO:B0041218 ! TNIK_HUMAN-Phosphothreonine581 relationship: transforms_into CCO:B0041219 ! TNIK_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0041220 ! TNIK_HUMAN-Phosphothreonine677 relationship: transforms_into CCO:B0071439 ! TNIK_HUMAN-Phosphoserine678 [Term] id: CCO:B0005604 name: SPTB2_HUMAN def: "Spectrin beta chain, brain 1" [UniProtKB:Q01082] synonym: "Beta-II spectrin" EXACT [UniProtKB:Q01082] synonym: "Fodrin beta chain" EXACT [UniProtKB:Q01082] synonym: "Spectrin, non-erythroid beta chain 1" EXACT [UniProtKB:Q01082] xref: EMBL:AAA60580.1 xref: EMBL:AAB28324.1 xref: EMBL:AAO15362.1 xref: EMBL:AAY24229.1 xref: EMBL:BAD92985.1 xref: EMBL:CAA06678.1 xref: EMBL:CAB91088.1 xref: UniProtKB:O60837 xref: UniProtKB:Q01082 xref: UniProtKB:Q16057 xref: UniProtKB:Q53R99 xref: UniProtKB:Q59ER3 xref: UniProtKB:Q8IX99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005667 ! SPTBN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006603 ! cdc5l-sptbn1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008499 ! rint1-sptbn1 physical interaction relationship: participates_in CCO:I0016346 ! map3k8-sptbn1 physical interaction relationship: participates_in CCO:I0016481 ! ikbke-sptbn1 physical interaction relationship: participates_in CCO:I0016748 ! map3k3-sptbn1 physical interaction relationship: participates_in CCO:I0017457 ! disc1-sptbn1 physical interaction relationship: participates_in CCO:I0017458 ! disc1-sptbn1-1 physical interaction relationship: participates_in CCO:I0017459 ! disc1-sptbn1-2 physical interaction relationship: participates_in CCO:I0017460 ! cep63-sptbn1 physical interaction relationship: participates_in CCO:I0017461 ! tnik-sptbn1 physical interaction relationship: participates_in CCO:I0017489 ! spta1-sptb2-1 direct interaction relationship: participates_in CCO:I0019197 ! spta1-sptb2-2 direct interaction relationship: participates_in CCO:I0019198 ! spta1-sptb2-3 direct interaction relationship: participates_in CCO:I0019201 ! spta2-sptb1-3 direct interaction relationship: participates_in CCO:I0019202 ! spta2-sptb2-2 direct interaction relationship: participates_in CCO:I0019203 ! spta2-sptb2-3 direct interaction relationship: participates_in CCO:I0019204 ! spta2-sptb2-4 direct interaction relationship: participates_in CCO:I0019205 ! spta2-sptb2-5 direct interaction relationship: participates_in CCO:I0019206 ! spta2-sptb2-6 direct interaction relationship: participates_in CCO:I0019207 ! spta2-sptb2-7 direct interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0014190 ! SPTB2_HUMAN-Phosphothreonine999 relationship: transforms_into CCO:B0014191 ! SPTB2_HUMAN-Phosphoserine1918 relationship: transforms_into CCO:B0014192 ! SPTB2_HUMAN-Phosphoserine2102 relationship: transforms_into CCO:B0014193 ! SPTB2_HUMAN-Phosphoserine2115 relationship: transforms_into CCO:B0014194 ! SPTB2_HUMAN-Phosphoserine2128 relationship: transforms_into CCO:B0014195 ! SPTB2_HUMAN-Phosphoserine2138 relationship: transforms_into CCO:B0014196 ! SPTB2_HUMAN-Phosphoserine2165 relationship: transforms_into CCO:B0014197 ! SPTB2_HUMAN-Phosphoserine2169 relationship: transforms_into CCO:B0014198 ! SPTB2_HUMAN-Phosphothreonine2195 relationship: transforms_into CCO:B0031375 ! SPTB2_HUMAN-Phosphotyrosine1805 relationship: transforms_into CCO:B0041197 ! SPTB2_HUMAN-Phosphoserine2164 relationship: transforms_into CCO:B0070831 ! SPTB2_HUMAN-Phosphothreonine2159 relationship: transforms_into CCO:B0070832 ! SPTB2_HUMAN-Phosphoserine2160 relationship: transforms_into CCO:B0070833 ! SPTB2_HUMAN-Phosphothreonine2187 relationship: transforms_into CCO:B0070834 ! SPTB2_HUMAN-Phosphothreonine2328 relationship: transforms_into CCO:B0070835 ! SPTB2_HUMAN-Phosphoserine2341 [Term] id: CCO:B0005605 name: CFTR_HUMAN def: "Cystic fibrosis transmembrane conductance regulator" [UniProtKB:P13569] synonym: "ATP-binding cassette transporter sub-family C member 7" EXACT [UniProtKB:P13569] synonym: "cAMP-dependent chloride channel" EXACT [UniProtKB:P13569] synonym: "CFTR" EXACT [UniProtKB:P13569] xref: EMBL:AAA35680.1 xref: EMBL:AAA51979.1 xref: EMBL:AAA51980.1 xref: EMBL:AAC13657.1 xref: EMBL:ABC79050.1 xref: EMBL:ABC79052.1 xref: EMBL:ABC79054.1 xref: EMBL:ABC79056.1 xref: EMBL:ABC87055.1 xref: EMBL:ABC87057.1 xref: EMBL:ABC87061.1 xref: EMBL:ABC87063.1 xref: EMBL:ABC87065.1 xref: EMBL:ABC87067.1 xref: EMBL:ABD72183.1 xref: EMBL:ABD72185.1 xref: EMBL:ABD72189.1 xref: EMBL:ABD72191.1 xref: EMBL:ABD72193.1 xref: EMBL:ABD72195.1 xref: EMBL:ABD72197.1 xref: EMBL:ABD72203.1 xref: EMBL:ABD72205.1 xref: EMBL:ABD72207.1 xref: EMBL:ABD72209.1 xref: EMBL:ABD72211.1 xref: EMBL:ABD72213.1 xref: EMBL:ABD72217.1 xref: EMBL:EAL24353.1 xref: UniProtKB:P13569 xref: UniProtKB:Q20BG8 xref: UniProtKB:Q20BH2 xref: UniProtKB:Q2I0A1 xref: UniProtKB:Q2I102 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004335 ! CFTR_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001500 ! ATP-binding and phosphorylation-dependent chloride channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001523 ! channel-conductance-controlling ATPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_function CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances relationship: has_function CCO:F0008027 ! nitric-oxide synthase binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0017486 ! cftr-edg4 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:I0017822 ! cftr-nhe2-1 physical interaction relationship: participates_in CCO:I0017934 ! rma1-cftr colocalization relationship: participates_in CCO:I0018286 ! cftr-pist-1 physical interaction relationship: participates_in CCO:I0018287 ! cftr-slc9a3r1-1 physical interaction relationship: participates_in CCO:I0018560 ! rma1-cftr-2 physical interaction relationship: participates_in CCO:I0018561 ! rma1-cftr-3 physical interaction relationship: participates_in CCO:I0018562 ! rma1-cftr-4 physical interaction relationship: participates_in CCO:I0018717 ! cftr-nhe2 physical interaction relationship: participates_in CCO:I0019328 ! cftr-slc9a3r2 physical interaction relationship: participates_in CCO:I0019329 ! cftr-slc9a3r2-1 physical interaction relationship: participates_in CCO:I0019460 ! rma1-cftr-1 physical interaction relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization relationship: transforms_into CCO:B0011183 ! CFTR_HUMAN-Phosphoserine660 relationship: transforms_into CCO:B0011184 ! CFTR_HUMAN-Phosphoserine686 relationship: transforms_into CCO:B0011185 ! CFTR_HUMAN-Phosphoserine700 relationship: transforms_into CCO:B0011186 ! CFTR_HUMAN-Phosphoserine712 relationship: transforms_into CCO:B0011187 ! CFTR_HUMAN-Phosphoserine737 relationship: transforms_into CCO:B0011188 ! CFTR_HUMAN-Phosphoserine753 relationship: transforms_into CCO:B0011189 ! CFTR_HUMAN-Phosphoserine768 relationship: transforms_into CCO:B0011190 ! CFTR_HUMAN-Phosphoserine790 relationship: transforms_into CCO:B0011191 ! CFTR_HUMAN-Phosphoserine795 relationship: transforms_into CCO:B0011192 ! CFTR_HUMAN-Phosphoserine813 relationship: transforms_into CCO:B0048194 ! CFTR_HUMAN-Phosphotyrosine515 [Term] id: CCO:B0005606 name: LIMK1_HUMAN def: "LIM domain kinase 1" [UniProtKB:P53667] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P53667] synonym: "LIMK-1" EXACT [UniProtKB:P53667] xref: EMBL:AAB17545.1 xref: EMBL:AAB17546.1 xref: EMBL:AAC13885.1 xref: EMBL:AAC13886.1 xref: EMBL:AAD25742.1 xref: EMBL:AAS07438.1 xref: EMBL:BAA05371.1 xref: UniProtKB:O15283 xref: UniProtKB:P53667 xref: UniProtKB:Q15820 xref: UniProtKB:Q15821 xref: UniProtKB:Q75MU3 xref: UniProtKB:Q9Y5Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004980 ! LIMK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006610 ! lats1-limk1-3 physical interaction relationship: participates_in CCO:I0006850 ! lats1-limk1-1 physical interaction relationship: participates_in CCO:I0006851 ! lats1-limk1-2 physical interaction relationship: participates_in CCO:I0007237 ! lats1-limk1-5 colocalization relationship: participates_in CCO:I0007730 ! lats1-limk1-4 physical interaction relationship: participates_in CCO:I0017275 ! pak2-limk1-2 phosphorylation relationship: participates_in CCO:I0018128 ! pak2-limk1-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0002548 ! positive regulation of axon extension relationship: transforms_into CCO:B0012698 ! LIMK1_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0012699 ! LIMK1_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0012700 ! LIMK1_HUMAN-Phosphothreonine508 relationship: transforms_into CCO:B0067671 ! LIMK1_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0067672 ! LIMK1_HUMAN-Phosphoserine307 [Term] id: CCO:B0005607 name: MYT1_HUMAN def: "Myelin transcription factor 1" [UniProtKB:Q01538] synonym: "MyT1" EXACT [UniProtKB:Q01538] synonym: "MyTI" EXACT [UniProtKB:Q01538] synonym: "PLPB1" EXACT [UniProtKB:Q01538] synonym: "Proteolipid protein-binding protein" EXACT [UniProtKB:Q01538] xref: EMBL:AAA59897.1 xref: EMBL:BAA74858.2 xref: EMBL:BAA83002.1 xref: EMBL:CAC17005.1 xref: UniProtKB:O94922 xref: UniProtKB:Q01538 xref: UniProtKB:Q9UPV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005153 ! MYT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006614 ! cdc2-myt1-1 phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005608 name: PTN6_HUMAN def: "Tyrosine-protein phosphatase non-receptor type 6" [UniProtKB:P29350] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P29350] synonym: "Hematopoietic cell protein-tyrosine phosphatase" EXACT [UniProtKB:P29350] synonym: "Protein-tyrosine phosphatase 1C" EXACT [UniProtKB:P29350] synonym: "Protein-tyrosine phosphatase SHP-1" EXACT [UniProtKB:P29350] synonym: "PTP-1C" EXACT [UniProtKB:P29350] synonym: "SH-PTP1" EXACT [UniProtKB:P29350] xref: EMBL:AAA35963.1 xref: EMBL:AAA36610.1 xref: EMBL:AAA82879.1 xref: EMBL:AAA82880.1 xref: EMBL:AAB51322.1 xref: EMBL:AAB51323.1 xref: EMBL:AAH02523.1 xref: EMBL:AAH07667.1 xref: EMBL:BAC81774.1 xref: EMBL:BAC81775.1 xref: EMBL:CAA43982.1 xref: UniProtKB:P29350 xref: UniProtKB:Q969V8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005399 ! PTPN6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006615 ! khdrbs1-ptpn6-1 physical interaction relationship: participates_in CCO:I0015978 ! ptpn6-pilra-1 physical interaction relationship: participates_in CCO:I0015979 ! ptpn6-lair1-1 physical interaction relationship: participates_in CCO:I0015980 ! ptpn6-grb2-1 physical interaction relationship: participates_in CCO:I0015981 ! ptpn6-sirpa-1 physical interaction relationship: participates_in CCO:I0017861 ! cd22-ptpn6-2 physical interaction relationship: participates_in CCO:I0017897 ! cd22-ptpn6-1 physical interaction relationship: participates_in CCO:I0017898 ! ptpn6-cd22-1 physical interaction relationship: participates_in CCO:I0017904 ! ptpn-6-cd22-2 physical interaction relationship: participates_in CCO:I0017930 ! ptpn6-pilra-2 physical interaction relationship: participates_in CCO:I0017931 ! ptpn6-pilra-3 physical interaction relationship: participates_in CCO:I0017932 ! ptpn6-pilra-4b physical interaction relationship: participates_in CCO:I0018551 ! pilra-ptpn6-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0031369 ! PTN6_HUMAN-Phosphotyrosine377 relationship: transforms_into CCO:B0031370 ! PTN6_HUMAN-Phosphotyrosine536 relationship: transforms_into CCO:B0036024 ! PTN6_HUMAN-Phosphotyrosine509 relationship: transforms_into CCO:B0069603 ! PTN6_HUMAN-Phosphotyrosine564 [Term] id: CCO:B0005609 name: FYN_HUMAN def: "Proto-oncogene tyrosine-protein kinase Fyn" [UniProtKB:P06241] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P06241] synonym: "p59-Fyn" EXACT [UniProtKB:P06241] synonym: "Protooncogene Syn" EXACT [UniProtKB:P06241] synonym: "SLK" EXACT [UniProtKB:P06241] xref: EMBL:AAA36615.1 xref: EMBL:AAB33113.2 xref: EMBL:AAC08285.1 xref: EMBL:AAH32496.1 xref: EMBL:CAI22300.1 xref: EMBL:CAI22301.1 xref: UniProtKB:P06241 xref: UniProtKB:Q16248 xref: UniProtKB:Q5R3A6 xref: UniProtKB:Q5R3A7 xref: UniProtKB:Q8N5D7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004666 ! FYN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006616 ! khdrbs1-fyn-1 physical interaction relationship: participates_in CCO:I0007088 ! khdrbs1-fyn-2 physical interaction relationship: participates_in CCO:I0007089 ! khdrbs1-fyn-3 physical interaction relationship: participates_in CCO:I0007480 ! fyn-med28-4 physical interaction relationship: participates_in CCO:I0016008 ! fyn-htr6-4 physical interaction relationship: participates_in CCO:I0016213 ! fyn-htr6-7 physical interaction relationship: participates_in CCO:I0017799 ! fyn-htr6-3 direct interaction relationship: participates_in CCO:I0017811 ! fyn-med28-1 phosphorylation relationship: participates_in CCO:I0017830 ! med28-fyn-1 physical interaction relationship: participates_in CCO:I0017831 ! fyn-med28-2 physical interaction relationship: participates_in CCO:I0017973 ! fyn-htr6-2 physical interaction relationship: participates_in CCO:I0018695 ! sphk2-fyn-1 direct interaction relationship: participates_in CCO:I0018722 ! fyn-htr6-5 physical interaction relationship: participates_in CCO:I0018723 ! fyn-htr6-6 physical interaction relationship: participates_in CCO:I0018728 ! fyn-med28-3 physical interaction relationship: participates_in CCO:I0018993 ! atxn1-fyn physical interaction relationship: participates_in CCO:I0019038 ! atxn1-fyn-1 physical interaction relationship: participates_in CCO:I0019211 ! fyn-htr6-1 physical interaction relationship: participates_in CCO:I0019268 ! prkd-fyn-1 physical interaction relationship: participates_in CCO:I0019269 ! prkd-fyn-2 physical interaction relationship: participates_in CCO:I0019280 ! fyn-fyn-10 phosphorylation relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: transforms_into CCO:B0011907 ! FYN_HUMAN-Phosphothreonine12 relationship: transforms_into CCO:B0011908 ! FYN_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0011909 ! FYN_HUMAN-Phosphotyrosine420 relationship: transforms_into CCO:B0011910 ! FYN_HUMAN-Phosphotyrosine531 relationship: transforms_into CCO:B0031321 ! FYN_HUMAN-Phosphotyrosine185 relationship: transforms_into CCO:B0066324 ! FYN_HUMAN-Phosphotyrosine213 relationship: transforms_into CCO:B0066325 ! FYN_HUMAN-Phosphotyrosine214 relationship: transforms_into CCO:B0066326 ! FYN_HUMAN-Phosphotyrosine440 [Term] id: CCO:B0005610 name: PLCG1_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1" [UniProtKB:P19174] synonym: "EC 3.1.4.11" EXACT [UniProtKB:P19174] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:P19174] synonym: "Phospholipase C-gamma-1" EXACT [UniProtKB:P19174] synonym: "PLC-148" EXACT [UniProtKB:P19174] synonym: "PLC-gamma-1" EXACT [UniProtKB:P19174] synonym: "PLC-II" EXACT [UniProtKB:P19174] xref: EMBL:AAA36452.1 xref: EMBL:ABB84466.1 xref: EMBL:CAA18537.1 xref: UniProtKB:P19174 xref: UniProtKB:Q2V575 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005334 ! PLCG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006617 ! khdrbs1-plcg1-1 physical interaction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0017631 ! npm_alk-pkc physical interaction relationship: participates_in CCO:I0017904 ! ptpn-6-cd22-2 physical interaction relationship: participates_in CCO:I0017906 ! cd22-plcg1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0013564 ! PLCG1_HUMAN-Phosphotyrosine771 relationship: transforms_into CCO:B0013565 ! PLCG1_HUMAN-Phosphotyrosine775 relationship: transforms_into CCO:B0013566 ! PLCG1_HUMAN-Phosphotyrosine783 relationship: transforms_into CCO:B0013567 ! PLCG1_HUMAN-Phosphotyrosine1253 relationship: transforms_into CCO:B0031364 ! PLCG1_HUMAN-Phosphotyrosine379 relationship: transforms_into CCO:B0031365 ! PLCG1_HUMAN-Phosphotyrosine481 relationship: transforms_into CCO:B0031366 ! PLCG1_HUMAN-Phosphotyrosine506 relationship: transforms_into CCO:B0031367 ! PLCG1_HUMAN-Phosphotyrosine977 relationship: transforms_into CCO:B0048357 ! PLCG1_HUMAN-Phosphoserine1263 [Term] id: CCO:B0005611 name: CBL_HUMAN def: "E3 ubiquitin-protein ligase CBL" [UniProtKB:P22681] synonym: "Casitas B-lineage lymphoma proto-oncogene" EXACT [UniProtKB:P22681] synonym: "EC 6.3.2.-" EXACT [UniProtKB:P22681] synonym: "Proto-oncogene c-CBL" EXACT [UniProtKB:P22681] synonym: "RING finger protein 55" EXACT [UniProtKB:P22681] synonym: "Signal transduction protein CBL" EXACT [UniProtKB:P22681] xref: EMBL:CAA40393.1 xref: UniProtKB:P22681 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004228 ! CBL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006619 ! khdrbs1-cbl-1 physical interaction relationship: participates_in CCO:I0007122 ! egfr-cbl1-1 direct interaction relationship: participates_in CCO:I0007123 ! egfr-cbl1-4 direct interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002802 ! positive regulation of receptor-mediated endocytosis relationship: transforms_into CCO:B0010944 ! CBL_HUMAN-Phosphotyrosine371 relationship: transforms_into CCO:B0010945 ! CBL_HUMAN-Phosphotyrosine552 relationship: transforms_into CCO:B0010946 ! CBL_HUMAN-Phosphoserine667 relationship: transforms_into CCO:B0010947 ! CBL_HUMAN-Phosphoserine669 relationship: transforms_into CCO:B0010948 ! CBL_HUMAN-Phosphotyrosine674 relationship: transforms_into CCO:B0010949 ! CBL_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0010950 ! CBL_HUMAN-Phosphotyrosine700 relationship: transforms_into CCO:B0010951 ! CBL_HUMAN-Phosphotyrosine774 relationship: transforms_into CCO:B0010952 ! CBL_HUMAN-Phosphoserine900 relationship: transforms_into CCO:B0031300 ! CBL_HUMAN-Phosphoserine668 [Term] id: CCO:B0005612 name: JAK3_HUMAN def: "Tyrosine-protein kinase JAK3" [UniProtKB:P52333] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P52333] synonym: "JAK-3" EXACT [UniProtKB:P52333] synonym: "Janus kinase 3" EXACT [UniProtKB:P52333] synonym: "L-JAK" EXACT [UniProtKB:P52333] synonym: "Leukocyte janus kinase" EXACT [UniProtKB:P52333] xref: EMBL:AAA19626.1 xref: EMBL:AAC50226.1 xref: EMBL:AAC50227.1 xref: EMBL:AAC50542.1 xref: EMBL:AAD22741.1 xref: EMBL:AAM44860.1 xref: UniProtKB:P52333 xref: UniProtKB:Q13259 xref: UniProtKB:Q13260 xref: UniProtKB:Q13611 xref: UniProtKB:Q9Y6S2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004909 ! JAK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006620 ! khdrbs1-jak3-1 physical interaction relationship: participates_in CCO:I0006622 ! khdrbs1-jak3-2 physical interaction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0007345 ! lepr-jak2-1 physical interaction relationship: transforms_into CCO:B0012434 ! JAK3_HUMAN-Phosphothreonine8 relationship: transforms_into CCO:B0012435 ! JAK3_HUMAN-Phosphotyrosine785 relationship: transforms_into CCO:B0012436 ! JAK3_HUMAN-Phosphotyrosine980 relationship: transforms_into CCO:B0048289 ! JAK3_HUMAN-Phosphoserine1027 relationship: transforms_into CCO:B0048290 ! JAK3_HUMAN-Phosphoserine1031 [Term] id: CCO:B0005613 name: SET1A_HUMAN def: "Histone-lysine N-methyltransferase SETD1A" [UniProtKB:O15047] synonym: "EC 2.1.1.43" EXACT [UniProtKB:O15047] synonym: "hSET1A" EXACT [UniProtKB:O15047] synonym: "Lysine N-methyltransferase 2F" EXACT [UniProtKB:O15047] synonym: "SET domain-containing protein 1A" EXACT [UniProtKB:O15047] synonym: "Set1/Ash2 histone methyltransferase complex subunit SET1" EXACT [UniProtKB:O15047] xref: EMBL:AAH27450.1 xref: EMBL:AAH35795.1 xref: EMBL:BAA20797.2 xref: UniProtKB:A6NP62 xref: UniProtKB:O15047 xref: UniProtKB:Q6PIF3 xref: UniProtKB:Q8TAJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005596 ! SETD1A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0006624 ! hcfc1-set1-1 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014018 ! SET1A_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0014019 ! SET1A_HUMAN-Phosphoserine470 [Term] id: CCO:B0005614 name: ASH2L_HUMAN def: "Set1/Ash2 histone methyltransferase complex subunit ASH2" [UniProtKB:Q9UBL3] synonym: "ASH2-like protein" EXACT [UniProtKB:Q9UBL3] xref: EMBL:AAC13563.1 xref: EMBL:AAC13564.1 xref: EMBL:AAH15936.1 xref: EMBL:BAA35127.1 xref: EMBL:BAA74520.1 xref: UniProtKB:O60659 xref: UniProtKB:O60660 xref: UniProtKB:Q96B62 xref: UniProtKB:Q9UBL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004107 ! ASH2L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001616 ! histone methyltransferase complex relationship: participates_in CCO:I0006030 ! hcfc1-many-4 physical interaction relationship: participates_in CCO:I0006625 ! hcfc1-ash2l-1 physical interaction relationship: participates_in CCO:I0006972 ! hcfc1-many-3 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007355 ! hcfc1-many-2 physical interaction relationship: participates_in CCO:I0007562 ! hcfc1-ash2l-2 physical interaction relationship: participates_in CCO:I0015154 ! ash2l-loc84661 physical interaction relationship: participates_in CCO:I0016336 ! mll2-rbq3-1 physical interaction relationship: participates_in CCO:I0017944 ! mll2-ash2l physical interaction relationship: participates_in CCO:I0017945 ! mll2-rbq3-3 physical interaction relationship: participates_in CCO:I0017946 ! mll2-ash2l-1 physical interaction relationship: participates_in CCO:I0018244 ! mll2-rbq3 physical interaction relationship: participates_in CCO:I0019913 ! ash2l-unc119 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005615 name: WDR5_HUMAN def: "WD repeat-containing protein 5" [UniProtKB:P61964] synonym: "BMP2-induced 3-kb gene protein" EXACT [UniProtKB:P61964] xref: EMBL:AAH01635.1 xref: EMBL:BAA91248.1 xref: EMBL:CAB66159.1 xref: UniProtKB:P61964 xref: UniProtKB:Q91VA5 xref: UniProtKB:Q9NWX7 xref: UniProtKB:Q9UGP9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005923 ! WDR5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006626 ! hcfc1-wdr5-1 physical interaction relationship: participates_in CCO:I0006815 ! cul4a-cul4b-2 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007717 ! cul4b-wdr5 physical interaction relationship: participates_in CCO:I0008534 ! wdr5-ddb1 physical interaction relationship: participates_in CCO:I0015306 ! mbip-wdr5 physical interaction relationship: participates_in CCO:I0019196 ! 12dt1-wdr5 physical interaction relationship: transforms_into CCO:B0014675 ! WDR5_HUMAN-Phosphoserine267 [Term] id: CCO:B0005616 name: PPARG_HUMAN def: "Peroxisome proliferator-activated receptor gamma" [UniProtKB:P37231] synonym: "Nuclear receptor subfamily 1 group C member 3" EXACT [UniProtKB:P37231] synonym: "PPAR-gamma" EXACT [UniProtKB:P37231] xref: EMBL:AAA80314.2 xref: EMBL:AAB04028.1 xref: EMBL:AAC51248.1 xref: EMBL:AAH06811.1 xref: EMBL:AAN38992.2 xref: EMBL:AAP35945.1 xref: EMBL:BAA18949.1 xref: EMBL:BAA23354.1 xref: EMBL:CAA62152.1 xref: EMBL:CAA62153.1 xref: UniProtKB:O00684 xref: UniProtKB:O00710 xref: UniProtKB:O14515 xref: UniProtKB:P37231 xref: UniProtKB:Q15178 xref: UniProtKB:Q15179 xref: UniProtKB:Q15180 xref: UniProtKB:Q15832 xref: UniProtKB:Q86U60 xref: UniProtKB:Q96J12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005362 ! PPARG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005187 ! transcription activator binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006286 ! retinoid X receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007878 ! arachidonic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006627 ! pparg-ep300 physical interaction relationship: participates_in CCO:I0017384 ! edf1-pparg-4 physical interaction relationship: participates_in CCO:I0017516 ! edf1-pparg-1 physical interaction relationship: participates_in CCO:I0017926 ! pparg-pparbp-1 physical interaction relationship: participates_in CCO:I0018207 ! edf1-pparg-3 physical interaction relationship: participates_in CCO:I0018852 ! edf1-pparg-2 physical interaction relationship: participates_in CCO:I0019476 ! pparg-brg1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002414 ! positive regulation of fat cell differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0013599 ! PPARG_HUMAN-Phosphoserine112 [Term] id: CCO:B0005617 name: TCP10_HUMAN def: "T-complex protein 10A homolog" [UniProtKB:Q12799] xref: EMBL:AAA82109.1 xref: EMBL:CAI39675.1 xref: EMBL:CAI42705.1 xref: UniProtKB:Q12799 xref: UniProtKB:Q5JR60 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005749 ! TCP10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006631 ! pard6a-tcp10-2 physical interaction relationship: participates_in CCO:I0006633 ! pard6a-tcp10-3 physical interaction [Term] id: CCO:B0005618 name: TRBM_HUMAN def: "Thrombomodulin precursor" [UniProtKB:P07204] synonym: "CD141 antigen" EXACT [UniProtKB:P07204] synonym: "Fetomodulin" EXACT [UniProtKB:P07204] synonym: "TM" EXACT [UniProtKB:P07204] xref: EMBL:AAA61175.1 xref: EMBL:AAB59508.1 xref: EMBL:AAH35602.2 xref: EMBL:AAH53357.1 xref: EMBL:AAM03232.1 xref: EMBL:BAA00149.1 xref: EMBL:CAA29045.1 xref: EMBL:CAB51954.1 xref: UniProtKB:P07204 xref: UniProtKB:Q8IV29 xref: UniProtKB:Q9UC32 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005825 ! THBD_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006635 ! thbd-f2-1 direct interaction relationship: participates_in CCO:I0006636 ! thbd-f2-2 direct interaction relationship: participates_in CCO:I0006637 ! thbd-f2-3 direct interaction relationship: participates_in CCO:I0006638 ! thbd-f2-4 direct interaction relationship: transforms_into CCO:B0014530 ! TRBM_HUMAN-3-hydroxyasparagine342 [Term] id: CCO:B0005619 name: UBQL4_HUMAN def: "Ubiquilin-4" [UniProtKB:Q9NRR5] synonym: "Ataxin-1 ubiquitin-like-interacting protein A1U" EXACT [UniProtKB:Q9NRR5] xref: EMBL:AAF19084.1 xref: EMBL:AAF80171.1 xref: EMBL:AAH06410.1 xref: EMBL:AAH18403.1 xref: EMBL:AAH63841.1 xref: EMBL:CAH72633.1 xref: UniProtKB:Q5VYA1 xref: UniProtKB:Q9BR98 xref: UniProtKB:Q9NRR5 xref: UniProtKB:Q9UHX4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005873 ! UBQLN4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006640 ! hrasls3-ubqln4 physical interaction relationship: participates_in CCO:I0006641 ! mdk-ubqln4 physical interaction relationship: participates_in CCO:I0006642 ! pin1-ubqln4 physical interaction relationship: participates_in CCO:I0006643 ! qscn6-ubqln4 physical interaction relationship: participates_in CCO:I0007609 ! ubqln4-mdk physical interaction relationship: participates_in CCO:I0007610 ! ubqln4-ptn-1 physical interaction relationship: participates_in CCO:I0007611 ! ubqln4-stmn1 physical interaction relationship: participates_in CCO:I0007612 ! ubqln4-ywhaq physical interaction relationship: participates_in CCO:I0007979 ! ubqln4-ptn physical interaction relationship: participates_in CCO:I0008206 ! ubqln4-smarcb1 physical interaction relationship: participates_in CCO:I0008363 ! ubqln4-appbp1 physical interaction relationship: participates_in CCO:I0008967 ! edn1-ubqln4 physical interaction relationship: participates_in CCO:I0016157 ! mllt6-ubqln4 physical interaction relationship: participates_in CCO:I0016158 ! ubqln4-znf205 physical interaction relationship: participates_in CCO:I0017523 ! areg-ubqln4 physical interaction relationship: participates_in CCO:I0017524 ! c19orf10-ubqln4 physical interaction relationship: participates_in CCO:I0017525 ! runx1t1-ubqln4 physical interaction relationship: participates_in CCO:I0017526 ! ccl21-ubqln4 physical interaction relationship: participates_in CCO:I0017527 ! dtx2-ubqln4 physical interaction relationship: participates_in CCO:I0017528 ! elf5-ubqln4 physical interaction relationship: participates_in CCO:I0017529 ! fgfbp1-ubqln4 physical interaction relationship: participates_in CCO:I0017530 ! fzd7-ubqln4 physical interaction relationship: participates_in CCO:I0017531 ! gabrd-ubqln4 physical interaction relationship: participates_in CCO:I0017532 ! igfbp6-ubqln4 physical interaction relationship: participates_in CCO:I0017533 ! ighm-ubqln4 physical interaction relationship: participates_in CCO:I0017534 ! mllt6-ubqln4-1 physical interaction relationship: participates_in CCO:I0017535 ! nme3-ubqln4 physical interaction relationship: participates_in CCO:I0017536 ! nphp1-ubqln4 physical interaction relationship: participates_in CCO:I0017537 ! ppic-ubqln4 physical interaction relationship: participates_in CCO:I0017538 ! scmh1-ubqln4 physical interaction relationship: participates_in CCO:I0017539 ! sgne1-ubqln4-1 physical interaction relationship: participates_in CCO:I0017540 ! tmepai-ubqln4 physical interaction relationship: participates_in CCO:I0017541 ! vip-ubqln4 physical interaction relationship: participates_in CCO:I0017542 ! znf205-ubqln4 physical interaction relationship: participates_in CCO:I0017594 ! ubqln4-dkk3 physical interaction relationship: participates_in CCO:I0017595 ! ubqln4-dtx2-1 physical interaction relationship: participates_in CCO:I0017596 ! ubqln4-pip5k2b-1 physical interaction relationship: participates_in CCO:I0017597 ! ubqln4-lat2 physical interaction relationship: participates_in CCO:I0018371 ! atxn1-ubqln4-1 colocalization relationship: participates_in CCO:I0018634 ! atxn1-ubqln4 physical interaction relationship: participates_in CCO:I0018635 ! atxn1-ubqln4-2 physical interaction relationship: participates_in CCO:I0018887 ! ubqln4-arl7 physical interaction relationship: participates_in CCO:I0018888 ! ubqln4-dmpk physical interaction relationship: participates_in CCO:I0018889 ! ubqln4-gdi1 physical interaction relationship: participates_in CCO:I0018890 ! ubqln4-hgs physical interaction relationship: participates_in CCO:I0018891 ! ubqln4-igfbp6 physical interaction relationship: participates_in CCO:I0018892 ! ubqln4-moap1 physical interaction relationship: participates_in CCO:I0018893 ! ubqln4-nme3 physical interaction relationship: participates_in CCO:I0018894 ! ubqln4-pip5k2b physical interaction relationship: participates_in CCO:I0018895 ! ubqln4-prkcabp physical interaction relationship: participates_in CCO:I0018896 ! ubqln4-robo2 physical interaction relationship: participates_in CCO:I0018897 ! ubqln4-scg2 physical interaction relationship: participates_in CCO:I0018898 ! ubqln4-tgfb1i1 physical interaction relationship: participates_in CCO:I0018899 ! ubqln4-traf2 physical interaction relationship: participates_in CCO:I0018900 ! ubqln4-zfpm2 physical interaction relationship: participates_in CCO:I0018901 ! ubqln4-impdh2 physical interaction relationship: participates_in CCO:I0018902 ! ubqln4-scg2-1 physical interaction relationship: participates_in CCO:I0018903 ! ubqln4-prkcabp-1 physical interaction relationship: participates_in CCO:I0018941 ! atxn1-ubqln4-3 physical interaction relationship: participates_in CCO:I0018963 ! atxn1-ubqln4-4 physical interaction relationship: participates_in CCO:I0019083 ! atxn1-ubqln4-5 physical interaction relationship: participates_in CCO:I0019673 ! ubqln4-rxra physical interaction relationship: transforms_into CCO:B0014571 ! UBQL4_HUMAN-Phosphoserine318 [Term] id: CCO:B0005621 name: P80C_HUMAN def: "Coilin" [UniProtKB:P38432] synonym: "p80" EXACT [UniProtKB:P38432] xref: EMBL:AAA36412.1 xref: EMBL:AAB81550.1 xref: EMBL:AAH10385.1 xref: UniProtKB:P38432 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005249 ! COIL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0002533 ! disulfide oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000179 ! female germ cell nucleus relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000750 ! Cajal body relationship: participates_in CCO:I0006649 ! mad1l1-coil physical interaction relationship: participates_in CCO:I0007628 ! coil-actn4 physical interaction relationship: participates_in CCO:I0008761 ! psma1-coil physical interaction relationship: participates_in CCO:I0008762 ! psme3-coil physical interaction relationship: participates_in CCO:I0008765 ! coil-psme3-1 physical interaction relationship: participates_in CCO:I0008786 ! coil-psme3 physical interaction relationship: participates_in CCO:I0017574 ! dnaja3-coil physical interaction relationship: participates_in CCO:I0017575 ! nif3l1-coil physical interaction relationship: participates_in CCO:I0017576 ! taf9-coil physical interaction relationship: participates_in CCO:I0017577 ! tceb3b-coil physical interaction relationship: participates_in CCO:I0017578 ! zbtb25-coil physical interaction relationship: participates_in CCO:I0018950 ! atxn1-coil physical interaction relationship: participates_in CCO:I0018969 ! atxn1-coil-1 physical interaction relationship: participates_in CCO:I0019088 ! atxn1-coil-2 physical interaction relationship: participates_in CCO:I0019132 ! coil-actn1 physical interaction relationship: participates_in CCO:I0019133 ! coil-actn2 physical interaction relationship: participates_in CCO:I0019134 ! coil-csnk2b physical interaction relationship: participates_in CCO:I0019135 ! coil-ncoa6ip physical interaction relationship: participates_in CCO:I0019136 ! coil-plekhg4 physical interaction relationship: participates_in CCO:I0019137 ! coil-prkcabp physical interaction relationship: participates_in CCO:I0019138 ! coil-snx6 physical interaction relationship: participates_in CCO:I0019139 ! coil-tfcp2 physical interaction relationship: participates_in CCO:I0019140 ! coil-znf277 physical interaction relationship: participates_in CCO:I0019141 ! coil-prkcabp-1 physical interaction relationship: participates_in CCO:I0019142 ! coil-actn1-1 physical interaction relationship: participates_in CCO:I0019143 ! coil-actn2-1 physical interaction relationship: participates_in CCO:I0019144 ! coil-ncoa6ip-1 physical interaction relationship: participates_in CCO:I0019145 ! coil-prkcabp-2 physical interaction relationship: transforms_into CCO:B0013362 ! P80C_HUMAN-Phosphothreonine122 relationship: transforms_into CCO:B0013363 ! P80C_HUMAN-Phosphothreonine303 relationship: transforms_into CCO:B0013364 ! P80C_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0069030 ! P80C_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0069031 ! P80C_HUMAN-Phosphothreonine290 relationship: transforms_into CCO:B0069032 ! P80C_HUMAN-Phosphoserine301 [Term] id: CCO:B0005622 name: RPA12_HUMAN def: "DNA-directed RNA polymerase I subunit RPA12" [UniProtKB:Q9P1U0] synonym: "Zinc ribbon domain-containing protein 1" EXACT [UniProtKB:Q9P1U0] xref: EMBL:AAF40469.1 xref: EMBL:AAG50159.1 xref: EMBL:AAG50160.1 xref: EMBL:AAH10898.1 xref: EMBL:AAH50608.1 xref: EMBL:CAG33390.1 xref: EMBL:CAI17577.1 xref: EMBL:CAI18176.1 xref: EMBL:CAI18538.1 xref: EMBL:CAI95579.1 xref: UniProtKB:Q9P1U0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005524 ! ZNRD1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006650 ! znrd1-gfi1b physical interaction relationship: participates_in CCO:I0015563 ! nono-znrd1 physical interaction relationship: participates_in CCO:I0016412 ! nfkbib-znrd1 physical interaction relationship: participates_in CCO:I0017570 ! znrd1-atxn2 physical interaction relationship: participates_in CCO:I0017573 ! znrd1-cic physical interaction relationship: participates_in CCO:I0017586 ! znrd1-sacs physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005623 name: MEOX2_HUMAN def: "Homeobox protein MOX-2" [UniProtKB:P50222] synonym: "Growth arrest-specific homeobox" EXACT [UniProtKB:P50222] synonym: "Mesenchyme homeobox 2" EXACT [UniProtKB:P50222] xref: EMBL:AAA58497.1 xref: EMBL:AAC06184.1 xref: EMBL:AAC33152.1 xref: EMBL:AAH17021.1 xref: EMBL:CAA57949.1 xref: UniProtKB:O75263 xref: UniProtKB:P50222 xref: UniProtKB:Q9UPL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005083 ! MEOX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006654 ! meox2-hspa2 physical interaction relationship: participates_in CCO:I0015425 ! meox2-samm50 physical interaction relationship: participates_in CCO:I0015515 ! krtap4_12-meox2 physical interaction relationship: participates_in CCO:I0015722 ! meox2-vip physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005624 name: SCAM1_HUMAN def: "Secretory carrier-associated membrane protein 1" [UniProtKB:O15126] synonym: "Secretory carrier membrane protein 1" EXACT [UniProtKB:O15126] xref: EMBL:AAB62722.1 xref: EMBL:AAC39864.1 xref: EMBL:AAH09787.1 xref: EMBL:AAH15065.1 xref: EMBL:AAH34048.1 xref: UniProtKB:O15126 xref: UniProtKB:O43587 xref: UniProtKB:Q96BX1 xref: UniProtKB:Q96QK5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005570 ! SCAMP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006657 ! scamp1-tp53 physical interaction [Term] id: CCO:B0005626 name: BEGIN_HUMAN def: "Brain-enriched guanylate kinase-associated protein" [UniProtKB:Q9BUH8] xref: EMBL:AAH02607.1 xref: EMBL:BAA95970.1 xref: EMBL:CAB99094.1 xref: UniProtKB:Q9BUH8 xref: UniProtKB:Q9NPU3 xref: UniProtKB:Q9P282 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004158 ! BEGAIN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006660 ! gfi1b-begain-1 physical interaction relationship: participates_in CCO:I0007654 ! gfi1b-begain physical interaction relationship: participates_in CCO:I0015186 ! begain-znf250 physical interaction relationship: participates_in CCO:I0015310 ! begain-znf417 physical interaction relationship: participates_in CCO:I0015497 ! begain-rfp physical interaction relationship: participates_in CCO:I0015511 ! begain-hgs physical interaction relationship: participates_in CCO:I0015620 ! begain-drr1 physical interaction relationship: participates_in CCO:I0015628 ! begain-zfp64 physical interaction relationship: transforms_into CCO:B0010785 ! BEGIN_HUMAN-Phosphoserine194 relationship: transforms_into CCO:B0010786 ! BEGIN_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0010787 ! BEGIN_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0010788 ! BEGIN_HUMAN-Phosphoserine465 relationship: transforms_into CCO:B0010789 ! BEGIN_HUMAN-Phosphoserine483 relationship: transforms_into CCO:B0010790 ! BEGIN_HUMAN-Phosphoserine502 relationship: transforms_into CCO:B0010791 ! BEGIN_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0031299 ! BEGIN_HUMAN-Phosphotyrosine137 [Term] id: CCO:B0005628 name: ALK_HUMAN def: "ALK tyrosine kinase receptor precursor" [UniProtKB:Q9UM73] synonym: "Anaplastic lymphoma kinase" EXACT [UniProtKB:Q9UM73] synonym: "CD246 antigen" EXACT [UniProtKB:Q9UM73] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q9UM73] xref: EMBL:AAB71619.1 xref: EMBL:AAC51104.1 xref: EMBL:AAX88892.1 xref: EMBL:AAX93126.1 xref: EMBL:AAY15027.1 xref: EMBL:BAD92714.1 xref: UniProtKB:Q4ZFX9 xref: UniProtKB:Q53QQ6 xref: UniProtKB:Q53RZ4 xref: UniProtKB:Q59FI3 xref: UniProtKB:Q9UM73 xref: UniProtKB:Q9Y4K6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004049 ! ALK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:I0016736 ! map3k3-alk physical interaction relationship: participates_in CCO:I0017631 ! npm_alk-pkc physical interaction relationship: participates_in CCO:I0017632 ! hsp-60-npm_alk physical interaction relationship: participates_in CCO:I0017633 ! grb2-npm_alk physical interaction relationship: participates_in CCO:I0017634 ! stat3-npm_alk physical interaction relationship: participates_in CCO:I0017635 ! irs1-npm_alk physical interaction relationship: participates_in CCO:I0017636 ! eif4b-npm_alk physical interaction relationship: participates_in CCO:I0017637 ! epha1-npm_alk physical interaction relationship: participates_in CCO:I0017638 ! ephb3-npm_alk physical interaction relationship: participates_in CCO:I0017639 ! map3k1-npm_alk physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0010499 ! ALK_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0010500 ! ALK_HUMAN-Phosphotyrosine1078 relationship: transforms_into CCO:B0010501 ! ALK_HUMAN-Phosphotyrosine1092 relationship: transforms_into CCO:B0010502 ! ALK_HUMAN-Phosphotyrosine1096 relationship: transforms_into CCO:B0010503 ! ALK_HUMAN-Phosphotyrosine1131 relationship: transforms_into CCO:B0010504 ! ALK_HUMAN-Phosphotyrosine1278 relationship: transforms_into CCO:B0010505 ! ALK_HUMAN-Phosphotyrosine1282 relationship: transforms_into CCO:B0010506 ! ALK_HUMAN-Phosphotyrosine1507 relationship: transforms_into CCO:B0010507 ! ALK_HUMAN-Phosphotyrosine1584 relationship: transforms_into CCO:B0010508 ! ALK_HUMAN-Phosphotyrosine1604 relationship: transforms_into CCO:B0065606 ! ALK_HUMAN-Phosphotyrosine1283 relationship: transforms_into CCO:B0065607 ! ALK_HUMAN-Phosphotyrosine1359 [Term] id: CCO:B0005629 name: KS6A4_HUMAN def: "Ribosomal protein S6 kinase alpha-4" [UniProtKB:O75676] synonym: "90 kDa ribosomal protein S6 kinase 4" EXACT [UniProtKB:O75676] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O75676] synonym: "Nuclear mitogen- and stress-activated protein kinase 2" EXACT [UniProtKB:O75676] synonym: "Ribosomal protein kinase B" EXACT [UniProtKB:O75676] synonym: "RSKB" EXACT [UniProtKB:O75676] xref: EMBL:AAC67395.1 xref: EMBL:BAD97281.1 xref: EMBL:CAA09009.1 xref: UniProtKB:O75585 xref: UniProtKB:O75676 xref: UniProtKB:Q53ES8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004961 ! RPS6KA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006672 ! rps6ka4-mapk3 physical interaction relationship: participates_in CCO:I0017383 ! mapk14-rps6ka4 physical interaction relationship: participates_in CCO:I0017646 ! rps6ka4-mapk14 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0012637 ! KS6A4_HUMAN-Phosphoserine196 relationship: transforms_into CCO:B0012638 ! KS6A4_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0012639 ! KS6A4_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0012640 ! KS6A4_HUMAN-Phosphoserine360 relationship: transforms_into CCO:B0012641 ! KS6A4_HUMAN-Phosphothreonine568 relationship: transforms_into CCO:B0012642 ! KS6A4_HUMAN-Phosphoserine681 relationship: transforms_into CCO:B0012643 ! KS6A4_HUMAN-Phosphoserine682 relationship: transforms_into CCO:B0012644 ! KS6A4_HUMAN-Phosphoserine737 [Term] id: CCO:B0005630 name: ANM2_HUMAN def: "Protein arginine N-methyltransferase 2" [UniProtKB:P55345] synonym: "EC 2.1.1.-" EXACT [UniProtKB:P55345] xref: EMBL:AAB48437.1 xref: EMBL:AAH00727.1 xref: EMBL:CAA67599.1 xref: EMBL:CAB52454.1 xref: UniProtKB:P55345 xref: UniProtKB:P78350 xref: UniProtKB:Q9BW15 xref: UniProtKB:Q9UMC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004064 ! PRMT2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006673 ! hrmt1l1-rara-1 physical interaction relationship: participates_in CCO:I0015636 ! flj12529-hrmt1l1 physical interaction relationship: participates_in CCO:I0017640 ! hrmt1l1-ncoa6-1 physical interaction relationship: participates_in CCO:I0017648 ! hrmt1l1-esr1-1 physical interaction relationship: participates_in CCO:I0017649 ! hrmt1l1-esr2-1 physical interaction relationship: participates_in CCO:I0017650 ! hrmt1l1-pgr-1 physical interaction relationship: participates_in CCO:I0017651 ! hrmt1l1-thrb-1 physical interaction relationship: participates_in CCO:I0017652 ! hrmt1l1-rxra-1 physical interaction relationship: participates_in CCO:I0017653 ! hrmt1l1-ppara-1 physical interaction relationship: participates_in CCO:I0017654 ! esr1-hrmt1l1-2 physical interaction relationship: participates_in CCO:I0017655 ! esr1-hrmt1l1-3 physical interaction relationship: participates_in CCO:I0017656 ! hrmt1l1-hrmt1l1-1 physical interaction relationship: participates_in CCO:I0017657 ! hrmt1l1-scarb1-1 physical interaction relationship: participates_in CCO:I0018079 ! hrmt1l1-esr1-4 physical interaction relationship: participates_in CCO:I0018351 ! esr1-hrmt1l1-1 physical interaction relationship: participates_in CCO:I0018465 ! bat2-hrmt1l1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005631 name: GP1BA_HUMAN def: "Platelet glycoprotein Ib alpha chain precursor" [UniProtKB:P07359] synonym: "Antigen CD42b-alpha" EXACT [UniProtKB:P07359] synonym: "CD42b antigen" EXACT [UniProtKB:P07359] synonym: "Glycoprotein Ibalpha" EXACT [UniProtKB:P07359] synonym: "GP-Ib alpha" EXACT [UniProtKB:P07359] synonym: "GPIb-alpha" EXACT [UniProtKB:P07359] synonym: "GPIbA" EXACT [UniProtKB:P07359] xref: EMBL:AAA52595.1 xref: EMBL:AAA52596.1 xref: EMBL:AAA69491.1 xref: EMBL:AAB22152.1 xref: EMBL:AAB22153.1 xref: EMBL:AAH27955.1 xref: EMBL:AAK71325.1 xref: EMBL:BAA12911.1 xref: EMBL:BAB12038.1 xref: EMBL:BAC10305.1 xref: UniProtKB:P07359 xref: UniProtKB:Q14441 xref: UniProtKB:Q16469 xref: UniProtKB:Q8N1F3 xref: UniProtKB:Q8NG39 xref: UniProtKB:Q9HDC7 xref: UniProtKB:Q9UEK1 xref: UniProtKB:Q9UQS4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004720 ! GP1BA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006675 ! gp1ba-f2 physical interaction relationship: transforms_into CCO:B0011965 ! GP1BA_HUMAN-Sulfotyrosine292 relationship: transforms_into CCO:B0011966 ! GP1BA_HUMAN-Sulfotyrosine294 relationship: transforms_into CCO:B0011967 ! GP1BA_HUMAN-Sulfotyrosine295 relationship: transforms_into CCO:B0066530 ! GP1BA_HUMAN-Phosphotyrosine292 relationship: transforms_into CCO:B0066531 ! GP1BA_HUMAN-Phosphotyrosine294 relationship: transforms_into CCO:B0066532 ! GP1BA_HUMAN-Phosphotyrosine295 relationship: transforms_into CCO:B0066533 ! GP1BA_HUMAN-Phosphoserine603 relationship: transforms_into CCO:B0066534 ! GP1BA_HUMAN-Phosphoserine606 [Term] id: CCO:B0005632 name: MYB_HUMAN def: "Myb proto-oncogene protein" [UniProtKB:P10242] synonym: "C-myb" EXACT [UniProtKB:P10242] xref: EMBL:AAA52030.1 xref: EMBL:AAA52031.1 xref: EMBL:AAA52032.1 xref: EMBL:AAB49034.1 xref: EMBL:AAB49035.1 xref: EMBL:AAB49036.1 xref: EMBL:AAB49037.1 xref: EMBL:AAB49038.1 xref: EMBL:AAB49039.1 xref: EMBL:AAC96326.1 xref: EMBL:AAH64955.1 xref: EMBL:CAA35503.1 xref: EMBL:CAA36371.1 xref: UniProtKB:P10242 xref: UniProtKB:P78391 xref: UniProtKB:P78392 xref: UniProtKB:P78525 xref: UniProtKB:P78526 xref: UniProtKB:Q14023 xref: UniProtKB:Q14024 xref: UniProtKB:Q9UE83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005140 ! MYB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:I0006679 ! myb-hipk2-1 physical interaction relationship: participates_in CCO:I0017667 ! myb-nlk physical interaction relationship: participates_in CCO:I0018579 ! mapk11-sp1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005633 name: FBW1A_HUMAN def: "F-box/WD repeat-containing protein 1A" [UniProtKB:Q9Y297] synonym: "E3RSIkappaB" EXACT [UniProtKB:Q9Y297] synonym: "F-box and WD repeats protein beta-TrCP" EXACT [UniProtKB:Q9Y297] synonym: "pIkappaBalpha-E3 receptor subunit" EXACT [UniProtKB:Q9Y297] xref: EMBL:AAD08702.1 xref: EMBL:AAF04464.1 xref: EMBL:AAH27994.1 xref: EMBL:CAA74572.1 xref: UniProtKB:Q9Y213 xref: UniProtKB:Q9Y297 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004619 ! BTRC_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006693 ! cul1-tip120a-3 physical interaction relationship: participates_in CCO:I0006696 ! cul1-skp1-2 physical interaction relationship: participates_in CCO:I0007600 ! btrc-skp1-1 physical interaction relationship: participates_in CCO:I0007601 ! btrc-wee1 physical interaction relationship: participates_in CCO:I0008695 ! btrc-trim9 physical interaction relationship: participates_in CCO:I0008720 ! btrc-ctnnb1-1 physical interaction relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0005634 name: SKP1_HUMAN def: "S-phase kinase-associated protein 1" [UniProtKB:P63208] synonym: "Cyclin A/CDK2-associated protein p19" EXACT [UniProtKB:P63208] synonym: "OCP-2" EXACT [UniProtKB:P63208] synonym: "OCP-II" EXACT [UniProtKB:P63208] synonym: "Organ of Corti protein 2" EXACT [UniProtKB:P63208] synonym: "p19A" EXACT [UniProtKB:P63208] synonym: "p19skp1" EXACT [UniProtKB:P63208] synonym: "RNA polymerase II elongation factor-like protein" EXACT [UniProtKB:P63208] synonym: "SIII" EXACT [UniProtKB:P63208] synonym: "Transcription elongation factor B" EXACT [UniProtKB:P63208] xref: EMBL:AAA79202.1 xref: EMBL:AAC50241.1 xref: EMBL:AAH09839.1 xref: EMBL:AAH20798.1 xref: EMBL:AAH25673.1 xref: EMBL:AAH65730.1 xref: EMBL:CAA87392.1 xref: UniProtKB:P34991 xref: UniProtKB:P63208 xref: UniProtKB:Q8TAY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010899 ! SKP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006242 ! fbxo25-cul1-1 physical interaction relationship: participates_in CCO:I0006243 ! fbxo4-cul1-2 physical interaction relationship: participates_in CCO:I0006244 ! fbxo7-cul1-1 physical interaction relationship: participates_in CCO:I0006693 ! cul1-tip120a-3 physical interaction relationship: participates_in CCO:I0006695 ! cul1-skp1-1 physical interaction relationship: participates_in CCO:I0006696 ! cul1-skp1-2 physical interaction relationship: participates_in CCO:I0006697 ! cul1-skp1-3 physical interaction relationship: participates_in CCO:I0006767 ! skp1a-skp2-1 direct interaction relationship: participates_in CCO:I0006768 ! skp1a-skp2-2 direct interaction relationship: participates_in CCO:I0006769 ! skp1a-skp2-3 direct interaction relationship: participates_in CCO:I0006797 ! cul1-cul1-7 physical interaction relationship: participates_in CCO:I0007106 ! cul1-cand1-1 physical interaction relationship: participates_in CCO:I0007598 ! skp2-skp1 physical interaction relationship: participates_in CCO:I0007599 ! fbxw11-skp1 physical interaction relationship: participates_in CCO:I0007600 ! btrc-skp1-1 physical interaction relationship: participates_in CCO:I0007733 ! skp2-cks1-4 physical interaction relationship: participates_in CCO:I0007943 ! fbxo11-skp1-1 physical interaction relationship: participates_in CCO:I0008720 ! btrc-ctnnb1-1 physical interaction relationship: participates_in CCO:I0008774 ! fbxl7-skp1 physical interaction relationship: participates_in CCO:I0008775 ! fbxl2-skp1 physical interaction relationship: participates_in CCO:I0008776 ! fbw5-skp1 physical interaction relationship: participates_in CCO:I0008777 ! fbw6-skp1 physical interaction relationship: participates_in CCO:I0008778 ! fbw7-skp1 physical interaction relationship: participates_in CCO:I0008779 ! fbxo41-skp1 physical interaction relationship: participates_in CCO:I0008780 ! fbox11-skp1 physical interaction relationship: participates_in CCO:I0008805 ! fbxo34-skp1a physical interaction relationship: participates_in CCO:I0008806 ! skp1a-fbxo34 physical interaction relationship: participates_in CCO:I0008820 ! ddx19b-skp1a physical interaction relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0005635 name: GNA13_HUMAN def: "Guanine nucleotide-binding protein subunit alpha-13" [UniProtKB:Q14344] synonym: "G alpha-13" EXACT [UniProtKB:Q14344] synonym: "G-protein subunit alpha-13" EXACT [UniProtKB:Q14344] xref: EMBL:AAA74235.1 xref: EMBL:AAH36756.1 xref: EMBL:AAM12616.1 xref: UniProtKB:Q14344 xref: UniProtKB:Q8TD70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004708 ! GNA13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006706 ! gna13-arhgef1-1 physical interaction relationship: participates_in CCO:I0006707 ! gna13-arhgef1-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: transforms_into CCO:B0011948 ! GNA13_HUMAN-Phosphothreonine203 [Term] id: CCO:B0005636 name: RAF1_HUMAN def: "RAF proto-oncogene serine/threonine-protein kinase" [UniProtKB:P04049] synonym: "C-RAF" EXACT [UniProtKB:P04049] synonym: "cRaf" EXACT [UniProtKB:P04049] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P04049] synonym: "Raf-1" EXACT [UniProtKB:P04049] xref: EMBL:AAA60247.1 xref: EMBL:AAH18119.1 xref: EMBL:AAP03432.1 xref: EMBL:ABY87557.1 xref: EMBL:CAA27204.1 xref: EMBL:EAW64134.1 xref: UniProtKB:B0LPH8 xref: UniProtKB:P04049 xref: UniProtKB:Q15278 xref: UniProtKB:Q9UC20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005421 ! RAF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006709 ! raf1-hras-2 physical interaction relationship: participates_in CCO:I0006916 ! raf1-rap1a-1 direct interaction relationship: participates_in CCO:I0007163 ! raf1-rap1a-2 direct interaction relationship: participates_in CCO:I0007280 ! raf1-hras-3 physical interaction relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0007740 ! raf1-hras physical interaction relationship: participates_in CCO:I0007834 ! raf1-hras-4 physical interaction relationship: participates_in CCO:I0007859 ! raf1-hras-1 physical interaction relationship: participates_in CCO:I0007860 ! raf1-pbk physical interaction relationship: participates_in CCO:I0016208 ! map2k2-raf1-1 physical interaction relationship: participates_in CCO:I0016272 ! raf1-ywhab-1 physical interaction relationship: participates_in CCO:I0016273 ! raf1-oip5 physical interaction relationship: participates_in CCO:I0016274 ! raf1-pkm2 physical interaction relationship: participates_in CCO:I0016275 ! raf1-cct3 physical interaction relationship: participates_in CCO:I0017276 ! pak2-raf1-2 phosphorylation relationship: participates_in CCO:I0017679 ! raf1-cps1-1 physical interaction relationship: participates_in CCO:I0017680 ! raf1-pkm2-2 physical interaction relationship: participates_in CCO:I0017681 ! raf1-ywhab-3 physical interaction relationship: participates_in CCO:I0017683 ! raf1-cct3-2 physical interaction relationship: participates_in CCO:I0017684 ! raf1-cops3-1 physical interaction relationship: participates_in CCO:I0017685 ! raf1-cps1-2 physical interaction relationship: participates_in CCO:I0017686 ! raf1-cps1-3 physical interaction relationship: participates_in CCO:I0017687 ! raf1-oip5-3 physical interaction relationship: participates_in CCO:I0017688 ! raf1-ywhab-4 physical interaction relationship: participates_in CCO:I0017760 ! raf1-oip5-2 physical interaction relationship: participates_in CCO:I0017766 ! hspcb-raf1-1 physical interaction relationship: participates_in CCO:I0017828 ! raf1-ywhaz-2 direct interaction relationship: participates_in CCO:I0018129 ! pak2-raf1-1 direct interaction relationship: participates_in CCO:I0019251 ! raf1-ywhab physical interaction relationship: participates_in CCO:I0019345 ! raf1-ywhaz-1 physical interaction relationship: participates_in CCO:I0019370 ! raf1-efemp1 physical interaction relationship: participates_in CCO:I0019371 ! raf1-pkm2-1 physical interaction relationship: participates_in CCO:I0019372 ! raf1-nudt14 physical interaction relationship: participates_in CCO:I0019373 ! raf1-cops3 physical interaction relationship: participates_in CCO:I0019374 ! raf1-rras2 physical interaction relationship: participates_in CCO:I0019375 ! raf1-cps1 physical interaction relationship: participates_in CCO:I0019376 ! raf1-ywhab-2 physical interaction relationship: participates_in CCO:I0019377 ! raf1-cct3-1 physical interaction relationship: participates_in CCO:I0019378 ! raf1-oip5-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002757 ! nerve growth factor receptor signaling pathway relationship: transforms_into CCO:B0013679 ! RAF1_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0013680 ! RAF1_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0013681 ! RAF1_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0013682 ! RAF1_HUMAN-Phosphothreonine268 relationship: transforms_into CCO:B0013683 ! RAF1_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0013684 ! RAF1_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0013685 ! RAF1_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0013686 ! RAF1_HUMAN-Phosphoserine499 relationship: transforms_into CCO:B0013687 ! RAF1_HUMAN-Phosphoserine621 relationship: transforms_into CCO:B0048364 ! RAF1_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0048365 ! RAF1_HUMAN-Phosphothreonine258 relationship: transforms_into CCO:B0048366 ! RAF1_HUMAN-Phosphothreonine269 [Term] id: CCO:B0005637 name: ELK1_HUMAN def: "ETS domain-containing protein Elk-1" [UniProtKB:P19419] xref: EMBL:AAA52384.1 xref: EMBL:AAC82466.1 xref: EMBL:AAD00862.1 xref: EMBL:AAH56150.1 xref: EMBL:BAA36616.1 xref: EMBL:BAA36617.1 xref: EMBL:CAA15659.1 xref: UniProtKB:O75606 xref: UniProtKB:O95058 xref: UniProtKB:P19419 xref: UniProtKB:Q969X8 xref: UniProtKB:Q9UJM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004559 ! ELK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006717 ! mapk3-elk1-1 phosphorylation relationship: participates_in CCO:I0006718 ! mapk1-elk1-1 phosphorylation relationship: participates_in CCO:I0020634 ! prei3-elk1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0011674 ! ELK1_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0011675 ! ELK1_HUMAN-Phosphothreonine336 relationship: transforms_into CCO:B0011676 ! ELK1_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0011677 ! ELK1_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0011678 ! ELK1_HUMAN-Phosphoserine422 [Term] id: CCO:B0005638 name: MK08_HUMAN def: "Mitogen-activated protein kinase 8" [UniProtKB:P45983] synonym: "c-Jun N-terminal kinase 1" EXACT [UniProtKB:P45983] synonym: "EC 2.7.11.24" EXACT [UniProtKB:P45983] synonym: "JNK-46" EXACT [UniProtKB:P45983] synonym: "Stress-activated protein kinase JNK1" EXACT [UniProtKB:P45983] xref: EMBL:AAA36131.1 xref: EMBL:AAC50607.1 xref: EMBL:AAC50610.1 xref: EMBL:AAC50611.1 xref: UniProtKB:P45983 xref: UniProtKB:Q15709 xref: UniProtKB:Q15712 xref: UniProtKB:Q15713 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005093 ! MAPK8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006719 ! mapk8-jun-1 phosphorylation relationship: participates_in CCO:I0019331 ! map2k4-mapk8-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000775 ! JUN phosphorylation relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0012946 ! MK08_HUMAN-Phosphothreonine183 relationship: transforms_into CCO:B0012947 ! MK08_HUMAN-Phosphotyrosine185 relationship: transforms_into CCO:B0012948 ! MK08_HUMAN-Phosphothreonine255 relationship: transforms_into CCO:B0012949 ! MK08_HUMAN-Phosphothreonine258 relationship: transforms_into CCO:B0012950 ! MK08_HUMAN-Phosphotyrosine259 relationship: transforms_into CCO:B0012951 ! MK08_HUMAN-Phosphotyrosine357 relationship: transforms_into CCO:B0012952 ! MK08_HUMAN-Phosphothreonine367 relationship: transforms_into CCO:B0012953 ! MK08_HUMAN-Phosphoserine377 [Term] id: CCO:B0005639 name: MSH6_HUMAN def: "DNA mismatch repair protein Msh6" [UniProtKB:P52701] synonym: "G/T mismatch-binding protein" EXACT [UniProtKB:P52701] synonym: "GTBP" EXACT [UniProtKB:P52701] synonym: "GTMBP" EXACT [UniProtKB:P52701] synonym: "MutS-alpha 160 kDa subunit" EXACT [UniProtKB:P52701] synonym: "p160" EXACT [UniProtKB:P52701] xref: EMBL:AAB39212.2 xref: EMBL:AAB47425.1 xref: EMBL:AAC50461.1 xref: EMBL:AAH04246.1 xref: EMBL:AAL87401.1 xref: EMBL:BAA23674.1 xref: EMBL:BAA23675.1 xref: UniProtKB:O43706 xref: UniProtKB:O43917 xref: UniProtKB:P52701 xref: UniProtKB:Q8TCX4 xref: UniProtKB:Q9BTB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005130 ! MSH6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006720 ! msh2-msh6-1 physical interaction relationship: participates_in CCO:I0006887 ! brca1-trrap-6 physical interaction relationship: participates_in CCO:I0007030 ! msh2-msh6 physical interaction relationship: participates_in CCO:I0007031 ! msh6-msh2 physical interaction relationship: participates_in CCO:I0007034 ! msh6-msh2-1 physical interaction relationship: participates_in CCO:I0007455 ! brca1-trrap-1 physical interaction relationship: participates_in CCO:I0007838 ! msh2-msh6-2 physical interaction relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0013016 ! MSH6_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0013017 ! MSH6_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0013018 ! MSH6_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0013019 ! MSH6_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0013020 ! MSH6_HUMAN-Phosphothreonine139 relationship: transforms_into CCO:B0013021 ! MSH6_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0013022 ! MSH6_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0013023 ! MSH6_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0013024 ! MSH6_HUMAN-Phosphoserine254 relationship: transforms_into CCO:B0013025 ! MSH6_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0013026 ! MSH6_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0013027 ! MSH6_HUMAN-Phosphoserine348 relationship: transforms_into CCO:B0013028 ! MSH6_HUMAN-Phosphoserine830 relationship: transforms_into CCO:B0013029 ! MSH6_HUMAN-Phosphothreonine924 relationship: transforms_into CCO:B0068296 ! MSH6_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0068297 ! MSH6_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0068298 ! MSH6_HUMAN-Phosphoserine200 [Term] id: CCO:B0005640 name: AP2A_HUMAN def: "Transcription factor AP-2 alpha" [UniProtKB:P05549] synonym: "Activating enhancer-binding protein 2 alpha" EXACT [UniProtKB:P05549] synonym: "Activator protein 2" EXACT [UniProtKB:P05549] synonym: "AP-2" EXACT [UniProtKB:P05549] synonym: "AP-2 transcription factor" EXACT [UniProtKB:P05549] synonym: "AP2-alpha" EXACT [UniProtKB:P05549] xref: EMBL:AAA02487.1 xref: EMBL:AAA35539.1 xref: EMBL:CAA36842.1 xref: EMBL:CAB59735.1 xref: UniProtKB:P05549 xref: UniProtKB:Q13777 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004072 ! TFAP2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0006721 ! p300-tfap2a-7 physical interaction relationship: participates_in CCO:I0006724 ! p300-tfap2a-2 physical interaction relationship: participates_in CCO:I0006725 ! p300-tfap2a-3 physical interaction relationship: participates_in CCO:I0006726 ! p300-tfap2a-4 physical interaction relationship: participates_in CCO:I0006727 ! p300-tfap2a-5 physical interaction relationship: participates_in CCO:I0006891 ! cited2-tfap2a-1 physical interaction relationship: participates_in CCO:I0007146 ! p300-tfap2a-1 physical interaction relationship: participates_in CCO:I0007417 ! p300-tfap2a-6 physical interaction relationship: participates_in CCO:I0007918 ! ap2a-ubc9-1 physical interaction relationship: participates_in CCO:I0007921 ! ubc9-ap2a-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0010563 ! AP2A_HUMAN-Phosphoserine239 [Term] id: CCO:B0005641 name: SRBS1_HUMAN def: "Sorbin and SH3 domain-containing protein 1" [UniProtKB:Q9BX66] synonym: "c-Cbl-associated protein" EXACT [UniProtKB:Q9BX66] synonym: "CAP" EXACT [UniProtKB:Q9BX66] synonym: "Ponsin" EXACT [UniProtKB:Q9BX66] synonym: "SH3 domain protein 5" EXACT [UniProtKB:Q9BX66] synonym: "SH3P12" EXACT [UniProtKB:Q9BX66] xref: EMBL:AAB93496.1 xref: EMBL:AAD27647.1 xref: EMBL:AAF22175.1 xref: EMBL:AAH42612.1 xref: EMBL:AAK37563.1 xref: EMBL:AAK37564.1 xref: EMBL:AAK37565.1 xref: EMBL:AAK57479.1 xref: EMBL:AAK57480.1 xref: EMBL:BAA92534.1 xref: EMBL:CAB55947.1 xref: EMBL:CAD34588.1 xref: EMBL:CAI14379.1 xref: UniProtKB:O43857 xref: UniProtKB:Q5T924 xref: UniProtKB:Q7LBE5 xref: UniProtKB:Q8IVK0 xref: UniProtKB:Q8IVQ4 xref: UniProtKB:Q96KF3 xref: UniProtKB:Q96KF4 xref: UniProtKB:Q9BX64 xref: UniProtKB:Q9BX65 xref: UniProtKB:Q9BX66 xref: UniProtKB:Q9P2Q0 xref: UniProtKB:Q9UFT2 xref: UniProtKB:Q9UHN7 xref: UniProtKB:Q9Y338 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005669 ! SORBS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006728 ! abl1-sorbs-2 physical interaction relationship: participates_in CCO:I0007751 ! abl1-sorbs-1 physical interaction relationship: participates_in CCO:I0019255 ! insr-sorbs-1 physical interaction relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0014201 ! SRBS1_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0014202 ! SRBS1_HUMAN-Phosphotyrosine134 relationship: transforms_into CCO:B0014203 ! SRBS1_HUMAN-Phosphothreonine349 relationship: transforms_into CCO:B0014204 ! SRBS1_HUMAN-Phosphoserine481 relationship: transforms_into CCO:B0014205 ! SRBS1_HUMAN-Phosphothreonine497 relationship: transforms_into CCO:B0014206 ! SRBS1_HUMAN-Phosphoserine556 relationship: transforms_into CCO:B0014207 ! SRBS1_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0070864 ! SRBS1_HUMAN-Phosphotyrosine79 relationship: transforms_into CCO:B0070865 ! SRBS1_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0070866 ! SRBS1_HUMAN-Phosphoserine472 relationship: transforms_into CCO:B0070867 ! SRBS1_HUMAN-Phosphoserine665 relationship: transforms_into CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: transforms_into CCO:B0070869 ! SRBS1_HUMAN-Phosphoserine945 relationship: transforms_into CCO:B0070870 ! SRBS1_HUMAN-Phosphoserine953 [Term] id: CCO:B0005642 name: ACTN2_HUMAN def: "Alpha-actinin-2" [UniProtKB:P35609] synonym: "Alpha-actinin skeletal muscle isoform 2" EXACT [UniProtKB:P35609] synonym: "F-actin cross-linking protein" EXACT [UniProtKB:P35609] xref: EMBL:AAA51583.1 xref: EMBL:AAA51584.1 xref: EMBL:AAH47901.2 xref: EMBL:AAH51770.2 xref: EMBL:CAB61269.1 xref: UniProtKB:P35609 xref: UniProtKB:Q86TF4 xref: UniProtKB:Q86TI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004022 ! ACTN2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_function CCO:F0008079 ! ZASP binding relationship: has_function CCO:F0008083 ! FATZ 1 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001136 ! pseudopodium relationship: located_in CCO:C0001729 ! dendritic spine relationship: participates_in CCO:I0006732 ! actn2-ttn-4 physical interaction relationship: participates_in CCO:I0006874 ! ttn-actn2-5 physical interaction relationship: participates_in CCO:I0007124 ! actn2-ttn-3 physical interaction relationship: participates_in CCO:I0007125 ! actn2-ttn-6 physical interaction relationship: participates_in CCO:I0007571 ! ttn-actn2-1 physical interaction relationship: participates_in CCO:I0007758 ! actn2-ttn-2 physical interaction relationship: participates_in CCO:I0017499 ! ang-actn2-1 physical interaction relationship: participates_in CCO:I0018189 ! ang-actn2-3 physical interaction relationship: participates_in CCO:I0018575 ! st7-actn2-1 physical interaction relationship: participates_in CCO:I0018791 ! ang-actn2-2 physical interaction relationship: participates_in CCO:I0019112 ! atxn2-actn2 physical interaction relationship: participates_in CCO:I0019118 ! atxn2-actn2-1 physical interaction relationship: participates_in CCO:I0019133 ! coil-actn2 physical interaction relationship: participates_in CCO:I0019143 ! coil-actn2-1 physical interaction relationship: participates_in CCO:I0019644 ! actn2-tuba1 physical interaction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0005643 name: O43397_HUMAN def: "Tumor protein D53" [UniProtKB:O43397] xref: EMBL:AAC98475.1 xref: UniProtKB:O43397 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005817 ! TPD52L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006740 ! hd53-hd53-3 physical interaction [Term] id: CCO:B0005644 name: Q9BWP7_HUMAN def: "Promyelocytic leukemia" [UniProtKB:Q9BWP7] xref: EMBL:AAH00080.2 xref: EMBL:AAH20994.1 xref: EMBL:AAP88913.1 xref: UniProtKB:Q8WUA0 xref: UniProtKB:Q9BWP7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005344 ! PML_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0006742 ! pml-suv39h1-2 physical interaction [Term] id: CCO:B0005645 name: OBSCN_HUMAN def: "Obscurin" [UniProtKB:Q5VST9] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q5VST9] synonym: "Obscurin-MLCK" EXACT [UniProtKB:Q5VST9] synonym: "Obscurin-myosin light chain kinase" EXACT [UniProtKB:Q5VST9] synonym: "Obscurin-RhoGEF" EXACT [UniProtKB:Q5VST9] xref: EMBL:AAH43916.1 xref: EMBL:BAB13382.1 xref: EMBL:BAB13465.2 xref: EMBL:CAC44768.1 xref: EMBL:CAC85745.1 xref: EMBL:CAC85746.1 xref: EMBL:CAC85747.1 xref: EMBL:CAC85749.1 xref: EMBL:CAC85750.1 xref: EMBL:CAC85751.1 xref: EMBL:CAC85752.1 xref: EMBL:CAC85753.1 xref: EMBL:CAC85754.1 xref: EMBL:CAC85755.1 xref: EMBL:CAH71670.2 xref: EMBL:CAH71673.1 xref: EMBL:CAI15072.1 xref: EMBL:CAI19283.1 xref: EMBL:CAI19284.1 xref: EMBL:CAI19285.1 xref: EMBL:CAJ76912.1 xref: UniProtKB:Q2A664 xref: UniProtKB:Q5T7G8 xref: UniProtKB:Q5T7G9 xref: UniProtKB:Q5VST9 xref: UniProtKB:Q5VSU2 xref: UniProtKB:Q86YC7 xref: UniProtKB:Q8NHN0 xref: UniProtKB:Q8NHN1 xref: UniProtKB:Q8NHN2 xref: UniProtKB:Q8NHN3 xref: UniProtKB:Q8NHN4 xref: UniProtKB:Q8NHN5 xref: UniProtKB:Q8NHN6 xref: UniProtKB:Q8NHN7 xref: UniProtKB:Q8NHN8 xref: UniProtKB:Q8NHN9 xref: UniProtKB:Q96AA2 xref: UniProtKB:Q9HCD3 xref: UniProtKB:Q9HCL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005228 ! OBSCN_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006743 ! ttn-obscn-3 physical interaction relationship: participates_in CCO:I0007004 ! ttn-obscn-1 physical interaction relationship: participates_in CCO:I0007378 ! calm1-obscn-1 physical interaction relationship: participates_in CCO:I0007452 ! ttn-obscn-2 physical interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0005646 name: FGFP1_HUMAN def: "Fibroblast growth factor-binding protein 1 precursor" [UniProtKB:Q14512] synonym: "17 kDa HBGF-binding protein" EXACT [UniProtKB:Q14512] synonym: "17 kDa heparin-binding growth factor-binding protein" EXACT [UniProtKB:Q14512] synonym: "FGF-binding protein 1" EXACT [UniProtKB:Q14512] synonym: "FGF-BP" EXACT [UniProtKB:Q14512] synonym: "FGF-BP1" EXACT [UniProtKB:Q14512] synonym: "FGFBP-1" EXACT [UniProtKB:Q14512] synonym: "HBp17" EXACT [UniProtKB:Q14512] xref: EMBL:AAA58636.1 xref: EMBL:AAD39216.1 xref: EMBL:AAH03628.1 xref: EMBL:AAH08910.1 xref: UniProtKB:Q14512 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004641 ! FGFBP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006744 ! fgfbp1-fgf2-3 direct interaction relationship: participates_in CCO:I0007295 ! fgfbp1-fgf2-1 direct interaction relationship: participates_in CCO:I0007296 ! fgfbp1-fgf2-2 direct interaction relationship: participates_in CCO:I0017529 ! fgfbp1-ubqln4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0005647 name: GCNL2_HUMAN def: "General control of amino acid synthesis protein 5-like 2" [UniProtKB:Q92830] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q92830] synonym: "Histone acetyltransferase GCN5" EXACT [UniProtKB:Q92830] synonym: "hsGCN5" EXACT [UniProtKB:Q92830] synonym: "STAF97" EXACT [UniProtKB:Q92830] xref: EMBL:AAC39769.1 xref: EMBL:AAC50641.1 xref: EMBL:AAH32743.1 xref: EMBL:AAH39907.1 xref: EMBL:AAI05978.1 xref: EMBL:EAW60803.1 xref: UniProtKB:Q8N1A2 xref: UniProtKB:Q92830 xref: UniProtKB:Q9UCW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004690 ! GCN5L2_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000011 ! histone acetyltransferase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006748 ! brca1-trrap-2 physical interaction relationship: participates_in CCO:I0006749 ! brca1-trrap-3 physical interaction relationship: participates_in CCO:I0006887 ! brca1-trrap-6 physical interaction relationship: participates_in CCO:I0007454 ! brca1-trrap physical interaction relationship: participates_in CCO:I0007455 ! brca1-trrap-1 physical interaction relationship: participates_in CCO:I0007595 ! brca1-trrap-5 physical interaction relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:I0015958 ! atxn7-trrap-3 physical interaction relationship: participates_in CCO:I0015959 ! atxn7-trrap-4 physical interaction relationship: participates_in CCO:I0016130 ! trrap-1-atxn7-1 physical interaction relationship: participates_in CCO:I0017762 ! atxn7-trrap-5 physical interaction relationship: participates_in CCO:I0017887 ! atxn7-trrap physical interaction relationship: participates_in CCO:I0017888 ! trrap-1-atxn7 physical interaction relationship: participates_in CCO:I0018691 ! err1-trrap-1 physical interaction relationship: participates_in CCO:I0018692 ! err1-trrap-2 physical interaction relationship: participates_in CCO:I0019400 ! atxn7-trrap-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0011925 ! GCNL2_HUMAN-Phosphotyrosine734 [Term] id: CCO:B0005648 name: DC1I1_HUMAN def: "Cytoplasmic dynein 1 intermediate chain 1" [UniProtKB:O14576] synonym: "Cytoplasmic dynein intermediate chain 1" EXACT [UniProtKB:O14576] synonym: "DH IC-1" EXACT [UniProtKB:O14576] synonym: "Dynein intermediate chain 1, cytosolic" EXACT [UniProtKB:O14576] xref: EMBL:AAB67047.2 xref: EMBL:AAB70113.1 xref: EMBL:AAC33443.1 xref: EMBL:AAD26852.1 xref: EMBL:BAC03639.1 xref: UniProtKB:O14576 xref: UniProtKB:Q9Y2X1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004442 ! DYNC1I1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006754 ! zw10_dync1l1_1 colocalization relationship: transforms_into CCO:B0011441 ! DC1I1_HUMAN-Phosphoserine635 [Term] id: CCO:B0005649 name: PPM1A_HUMAN def: "Protein phosphatase 1A" [UniProtKB:P35813] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P35813] synonym: "IA" EXACT [UniProtKB:P35813] synonym: "PP2C-alpha" EXACT [UniProtKB:P35813] synonym: "Protein phosphatase 2C isoform alpha" EXACT [UniProtKB:P35813] xref: EMBL:AAB21784.1 xref: EMBL:AAC28354.1 xref: EMBL:AAH26691.1 xref: EMBL:AAH63243.1 xref: UniProtKB:O75551 xref: UniProtKB:P35813 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005366 ! PPM1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006759 ! sgol1-ppm1a-1 physical interaction relationship: participates_in CCO:I0006762 ! sgol2-ppm1a-1 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0013604 ! PPM1A_HUMAN-Phosphoserine377 [Term] id: CCO:B0005650 name: SHOC2_HUMAN def: "Leucine-rich repeat protein SHOC-2" [UniProtKB:Q9UQ13] synonym: "Ras-binding protein Sur-8" EXACT [UniProtKB:Q9UQ13] xref: EMBL:AAC25698.1 xref: EMBL:AAC39856.1 xref: EMBL:AAH50445.1 xref: EMBL:BAA74885.2 xref: UniProtKB:O76063 xref: UniProtKB:Q9UQ13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005611 ! SHOC2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006766 ! shoc2-erbb2ip-2 physical interaction relationship: participates_in CCO:I0007382 ! shoc2-erbb2ip physical interaction relationship: participates_in CCO:I0007383 ! shoc2-erbb2ip-3 physical interaction relationship: participates_in CCO:I0007466 ! shoc2-erbb2ip-1 physical interaction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0005651 name: XRCC4_HUMAN def: "DNA repair protein XRCC4" [UniProtKB:Q13426] synonym: "X-ray repair cross-complementing protein 4" EXACT [UniProtKB:Q13426] xref: EMBL:AAC50339.1 xref: EMBL:AAD47297.1 xref: EMBL:AAD47298.1 xref: EMBL:AAH05259.1 xref: EMBL:AAH16314.1 xref: EMBL:AAP35880.1 xref: EMBL:AAX14046.1 xref: EMBL:BAB20668.1 xref: UniProtKB:Q13426 xref: UniProtKB:Q9BS72 xref: UniProtKB:Q9UP94 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005946 ! XRCC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006771 ! lig4-xrcc4-1 direct interaction relationship: participates_in CCO:I0015102 ! actn1-xrcc4 physical interaction relationship: participates_in CCO:I0016140 ! xrcc4-aprataxin-1 physical interaction relationship: participates_in CCO:I0017599 ! aptx-xrcc4 physical interaction relationship: participates_in CCO:I0020216 ! xrcc4-chd3 physical interaction relationship: transforms_into CCO:B0014719 ! XRCC4_HUMAN-Phosphoserine260 relationship: transforms_into CCO:B0014720 ! XRCC4_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0071895 ! XRCC4_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0071896 ! XRCC4_HUMAN-Phosphoserine328 [Term] id: CCO:B0005652 name: ESR1_HUMAN def: "Estrogen receptor" [UniProtKB:P03372] synonym: "ER" EXACT [UniProtKB:P03372] synonym: "ER-alpha" EXACT [UniProtKB:P03372] synonym: "Estradiol receptor" EXACT [UniProtKB:P03372] synonym: "Nuclear receptor subfamily 3 group A member 1" EXACT [UniProtKB:P03372] xref: EMBL:AAA52399.1 xref: EMBL:AAB00115.1 xref: EMBL:AAD52984.1 xref: EMBL:AAQ91815.1 xref: EMBL:CAA27284.1 xref: EMBL:CAA51528.1 xref: EMBL:CAA99436.1 xref: EMBL:CAI42285.1 xref: UniProtKB:P03372 xref: UniProtKB:Q13511 xref: UniProtKB:Q14276 xref: UniProtKB:Q9NU51 xref: UniProtKB:Q9UDZ7 xref: UniProtKB:Q9UIS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004590 ! ESR1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0004355 ! nitric-oxide synthase regulator activity relationship: has_function CCO:F0004376 ! estrogen receptor activity relationship: has_function CCO:F0005682 ! hormone binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000806 ! chromatin remodeling complex relationship: located_in CCO:C0001002 ! T-tubule relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001727 ! terminal button relationship: located_in CCO:C0001733 ! perikaryon relationship: participates_in CCO:I0006772 ! brca1-esr1 physical interaction relationship: participates_in CCO:I0006773 ! esr1-brca1-10 physical interaction relationship: participates_in CCO:I0006774 ! brca1-esr1-2 physical interaction relationship: participates_in CCO:I0006775 ! esr1-brca1-11 physical interaction relationship: participates_in CCO:I0006805 ! esr1-mdm2 physical interaction relationship: participates_in CCO:I0006914 ! esr1-brca1-5 direct interaction relationship: participates_in CCO:I0006915 ! esr1-brca1-7 direct interaction relationship: participates_in CCO:I0006925 ! esr1-mdm2-1 physical interaction relationship: participates_in CCO:I0007017 ! brca1-esr1-4 direct interaction relationship: participates_in CCO:I0007018 ! brca1-esr1-5 direct interaction relationship: participates_in CCO:I0007492 ! esr1-brca1-1 direct interaction relationship: participates_in CCO:I0007493 ! esr1-brca1-2 direct interaction relationship: participates_in CCO:I0007494 ! esr1-brca1-3 direct interaction relationship: participates_in CCO:I0007495 ! esr1-brca1-6 direct interaction relationship: participates_in CCO:I0016204 ! esr1-foxo1a physical interaction relationship: participates_in CCO:I0016336 ! mll2-rbq3-1 physical interaction relationship: participates_in CCO:I0017648 ! hrmt1l1-esr1-1 physical interaction relationship: participates_in CCO:I0017654 ! esr1-hrmt1l1-2 physical interaction relationship: participates_in CCO:I0017655 ! esr1-hrmt1l1-3 physical interaction relationship: participates_in CCO:I0018079 ! hrmt1l1-esr1-4 physical interaction relationship: participates_in CCO:I0018107 ! esr1-mll2 direct interaction relationship: participates_in CCO:I0018244 ! mll2-rbq3 physical interaction relationship: participates_in CCO:I0018351 ! esr1-hrmt1l1-1 physical interaction relationship: participates_in CCO:I0018417 ! ncoa6-esr1-1 physical interaction relationship: participates_in CCO:I0018422 ! ncoa6-esr1-2 physical interaction relationship: participates_in CCO:I0018718 ! esr1-foxo1a-1 physical interaction relationship: participates_in CCO:I0018719 ! esr1-foxo1a-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0002235 ! neuroprotection relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression relationship: transforms_into CCO:B0011768 ! ESR1_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0011769 ! ESR1_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0011770 ! ESR1_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0011771 ! ESR1_HUMAN-Phosphoserine167 relationship: transforms_into CCO:B0011772 ! ESR1_HUMAN-Phosphotyrosine537 relationship: transforms_into CCO:B0036003 ! ESR1_HUMAN-Phosphothreonine7 relationship: transforms_into CCO:B0036004 ! ESR1_HUMAN-Phosphoserine10 [Term] id: CCO:B0005653 name: RANG_HUMAN def: "Ran-specific GTPase-activating protein" [UniProtKB:P43487] synonym: "Ran-binding protein 1" EXACT [UniProtKB:P43487] synonym: "RanBP1" EXACT [UniProtKB:P43487] xref: EMBL:BAA07269.1 xref: EMBL:CAA58592.1 xref: EMBL:CAG30442.1 xref: UniProtKB:P43487 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005424 ! RANBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006776 ! ran-ranbp1-1 physical interaction relationship: participates_in CCO:I0006777 ! ran-ranbp1-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0013701 ! RANG_HUMAN-Phosphothreonine13 relationship: transforms_into CCO:B0013702 ! RANG_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0013703 ! RANG_HUMAN-Phosphothreonine15 relationship: transforms_into CCO:B0013704 ! RANG_HUMAN-Phosphothreonine18 relationship: transforms_into CCO:B0013705 ! RANG_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0013706 ! RANG_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0069732 ! RANG_HUMAN-Phosphothreonine7 [Term] id: CCO:B0005654 name: FBXW7_HUMAN def: "F-box/WD repeat-containing protein 7" [UniProtKB:Q969H0] synonym: "Archipelago homolog" EXACT [UniProtKB:Q969H0] synonym: "F-box and WD-40 domain-containing protein 7" EXACT [UniProtKB:Q969H0] synonym: "F-box protein FBX30" EXACT [UniProtKB:Q969H0] synonym: "hAgo" EXACT [UniProtKB:Q969H0] synonym: "hCdc4" EXACT [UniProtKB:Q969H0] synonym: "SEL-10" EXACT [UniProtKB:Q969H0] xref: EMBL:AAG16640.1 xref: EMBL:AAH37320.1 xref: EMBL:AAI17245.1 xref: EMBL:AAI17247.1 xref: EMBL:AAK57547.1 xref: EMBL:AAK60269.1 xref: EMBL:AAL06290.1 xref: EMBL:AAL06291.1 xref: EMBL:AAL07271.1 xref: EMBL:BAA91986.1 xref: EMBL:CAH18160.1 xref: UniProtKB:Q68DR0 xref: UniProtKB:Q969H0 xref: UniProtKB:Q96A16 xref: UniProtKB:Q96LE0 xref: UniProtKB:Q96RI2 xref: UniProtKB:Q9NUX6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004628 ! FBXW7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006786 ! myc-fbxw7 physical interaction relationship: participates_in CCO:I0008778 ! fbw7-skp1 physical interaction relationship: transforms_into CCO:B0011874 ! FBXW7_HUMAN-Phosphoserine26 [Term] id: CCO:B0005655 name: FKB1A_HUMAN def: "Peptidyl-prolyl cis-trans isomerase FKBP1A" [UniProtKB:P62942] synonym: "12 kDa FKBP" EXACT [UniProtKB:P62942] synonym: "EC 5.2.1.8" EXACT [UniProtKB:P62942] synonym: "FK506-binding protein 1A" EXACT [UniProtKB:P62942] synonym: "FKBP-12" EXACT [UniProtKB:P62942] synonym: "FKBP-1A" EXACT [UniProtKB:P62942] synonym: "Immunophilin FKBP12" EXACT [UniProtKB:P62942] synonym: "PPIase FKBP1A" EXACT [UniProtKB:P62942] synonym: "Rotamase" EXACT [UniProtKB:P62942] xref: EMBL:AAA35844.1 xref: EMBL:AAA58472.1 xref: EMBL:AAA58476.1 xref: EMBL:AAH01925.3 xref: EMBL:AAH05147.1 xref: EMBL:AAP35729.1 xref: EMBL:CAA36462.1 xref: EMBL:CAA39272.1 xref: EMBL:CAG28541.1 xref: EMBL:CAG46965.1 xref: EMBL:CAH72382.1 xref: EMBL:CAI22728.1 xref: UniProtKB:P20071 xref: UniProtKB:P62942 xref: UniProtKB:Q4VC47 xref: UniProtKB:Q6FGD9 xref: UniProtKB:Q6LEU3 xref: UniProtKB:Q9H103 xref: UniProtKB:Q9H566 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004647 ! FKBP1A_human relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006794 ! fkbp1a-frap1-1 direct interaction relationship: participates_in CCO:I0015858 ! fkbp1a-tgfbr1-1 direct interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0005656 name: DTL_HUMAN def: "Denticleless protein homolog" [UniProtKB:Q9NZJ0] synonym: "Ddb1- and Cul4-associated factor 2" EXACT [UniProtKB:Q9NZJ0] synonym: "Lethal(2) denticleless protein homolog" EXACT [UniProtKB:Q9NZJ0] synonym: "Retinoic acid-regulated nuclear matrix-associated protein" EXACT [UniProtKB:Q9NZJ0] xref: EMBL:AAF35182.1 xref: EMBL:AAH33297.1 xref: EMBL:AAH33540.1 xref: EMBL:AAK54706.1 xref: EMBL:ABG23317.1 xref: EMBL:BAA91355.1 xref: EMBL:BAA91552.1 xref: EMBL:BAA91586.1 xref: EMBL:BAB55267.1 xref: EMBL:CAH70697.1 xref: EMBL:CAH73803.1 xref: UniProtKB:Q5VT77 xref: UniProtKB:Q96SN0 xref: UniProtKB:Q9NW03 xref: UniProtKB:Q9NW34 xref: UniProtKB:Q9NWM5 xref: UniProtKB:Q9NZJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004516 ! DTL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006808 ! cul4b-ddb1-2 physical interaction relationship: participates_in CCO:I0006817 ! l2dtl-cul4b physical interaction relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0008525 ! l2dt1-ddb1 physical interaction relationship: participates_in CCO:I0008530 ! l2dtl-ddb1 physical interaction relationship: participates_in CCO:I0019196 ! 12dt1-wdr5 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0011594 ! DTL_HUMAN-Phosphoserine426 relationship: transforms_into CCO:B0011595 ! DTL_HUMAN-Phosphothreonine516 relationship: transforms_into CCO:B0011596 ! DTL_HUMAN-Phosphoserine599 relationship: transforms_into CCO:B0011597 ! DTL_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0064891 ! DTL_HUMAN-Phosphoserine485 relationship: transforms_into CCO:B0064892 ! DTL_HUMAN-Phosphoserine490 relationship: transforms_into CCO:B0064893 ! DTL_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0064894 ! DTL_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0064895 ! DTL_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0064896 ! DTL_HUMAN-Phosphoserine557 relationship: transforms_into CCO:B0064897 ! DTL_HUMAN-Phosphoserine676 relationship: transforms_into CCO:B0064898 ! DTL_HUMAN-Phosphoserine679 relationship: transforms_into CCO:B0064899 ! DTL_HUMAN-Phosphoserine681 relationship: transforms_into CCO:B0064900 ! DTL_HUMAN-Phosphoserine682 relationship: transforms_into CCO:B0064901 ! DTL_HUMAN-Phosphothreonine684 [Term] id: CCO:B0005657 name: TLE2_HUMAN def: "Transducin-like enhancer protein 2" [UniProtKB:Q04725] synonym: "ESG2" EXACT [UniProtKB:Q04725] xref: EMBL:AAA61193.1 xref: EMBL:AAD38075.1 xref: EMBL:AAH17364.1 xref: UniProtKB:Q04725 xref: UniProtKB:Q8WVY0 xref: UniProtKB:Q9Y6S0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005789 ! TLE2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006809 ! cul4b-tle2 physical interaction relationship: participates_in CCO:I0006818 ! tle2-ddb1-1 physical interaction relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0008522 ! tle2-ddb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014394 ! TLE2_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0014395 ! TLE2_HUMAN-Phosphoserine249 relationship: transforms_into CCO:B0014396 ! TLE2_HUMAN-Phosphothreonine253 relationship: transforms_into CCO:B0071411 ! TLE2_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0071412 ! TLE2_HUMAN-Phosphoserine281 [Term] id: CCO:B0005658 name: DDB2_HUMAN def: "DNA damage-binding protein 2" [UniProtKB:Q92466] synonym: "Damage-specific DNA-binding protein 2" EXACT [UniProtKB:Q92466] synonym: "DDB p48 subunit" EXACT [UniProtKB:Q92466] synonym: "DDBb" EXACT [UniProtKB:Q92466] synonym: "UV-damaged DNA-binding protein 2" EXACT [UniProtKB:Q92466] synonym: "UV-DDB 2" EXACT [UniProtKB:Q92466] xref: EMBL:AAB07897.1 xref: EMBL:AAH00093.1 xref: EMBL:AAO25655.1 xref: EMBL:AAP35803.1 xref: EMBL:BAD12557.1 xref: EMBL:BAD12558.1 xref: EMBL:BAD12559.1 xref: EMBL:BAD12560.1 xref: UniProtKB:Q76E54 xref: UniProtKB:Q76E55 xref: UniProtKB:Q76E56 xref: UniProtKB:Q76E57 xref: UniProtKB:Q92466 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004451 ! DDB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006810 ! ddb1-ddb2-1 physical interaction relationship: participates_in CCO:I0006811 ! cul4a-ddb2 physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0008523 ! ddb1-ddb2 physical interaction relationship: transforms_into CCO:B0011457 ! DDB2_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0011458 ! DDB2_HUMAN-Phosphoserine26 [Term] id: CCO:B0005660 name: RBBP5_HUMAN def: "Retinoblastoma-binding protein 5" [UniProtKB:Q15291] synonym: "RBBP-5" EXACT [UniProtKB:Q15291] synonym: "Retinoblastoma-binding protein RBQ-3" EXACT [UniProtKB:Q15291] xref: EMBL:AAH37284.1 xref: EMBL:AAH53856.1 xref: EMBL:AAH75059.1 xref: EMBL:AAH75060.1 xref: EMBL:BAF82826.1 xref: EMBL:CAA59446.1 xref: EMBL:CAI15286.1 xref: EMBL:CAI15287.1 xref: EMBL:EAW91537.1 xref: EMBL:EAW91538.1 xref: UniProtKB:A8K272 xref: UniProtKB:Q15291 xref: UniProtKB:Q7Z6D8 xref: UniProtKB:Q8NDZ7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005439 ! RBBP5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006305 ! mll-hcfc2-2 physical interaction relationship: participates_in CCO:I0006816 ! cul4a-cul4b-3 physical interaction relationship: participates_in CCO:I0006819 ! rbbp5-cul4a physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0008524 ! rbbp5-wdr5-1 physical interaction relationship: participates_in CCO:I0008569 ! mll-hcfc2-1 physical interaction relationship: participates_in CCO:I0016336 ! mll2-rbq3-1 physical interaction relationship: participates_in CCO:I0017944 ! mll2-ash2l physical interaction relationship: participates_in CCO:I0017945 ! mll2-rbq3-3 physical interaction relationship: participates_in CCO:I0017946 ! mll2-ash2l-1 physical interaction relationship: participates_in CCO:I0018244 ! mll2-rbq3 physical interaction relationship: transforms_into CCO:B0013720 ! RBBP5_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0013721 ! RBBP5_HUMAN-Phosphothreonine193 relationship: transforms_into CCO:B0013722 ! RBBP5_HUMAN-Phosphothreonine252 relationship: transforms_into CCO:B0013723 ! RBBP5_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0013724 ! RBBP5_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0013725 ! RBBP5_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0013726 ! RBBP5_HUMAN-Phosphoserine497 [Term] id: CCO:B0005661 name: IPO7_HUMAN def: "Importin-7" [UniProtKB:O95373] synonym: "Imp7" EXACT [UniProtKB:O95373] synonym: "Ran-binding protein 7" EXACT [UniProtKB:O95373] synonym: "RanBP7" EXACT [UniProtKB:O95373] xref: EMBL:AAC68903.1 xref: EMBL:AAI14930.1 xref: EMBL:CAB70698.1 xref: EMBL:CAC17609.1 xref: EMBL:EAW68593.1 xref: UniProtKB:A6NNM5 xref: UniProtKB:O95373 xref: UniProtKB:Q1RMF7 xref: UniProtKB:Q9H177 xref: UniProtKB:Q9NTE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004901 ! IPO7_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001985 ! Ran GTPase binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0006829 ! ran-xpot-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016545 ! ikbkg-ipo7 physical interaction relationship: participates_in CCO:I0017049 ! tnfrsf1b-ipo7 physical interaction relationship: participates_in CCO:I0017078 ! tradd-ipo7 physical interaction relationship: participates_in CCO:I0017150 ! traf6-ipo7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012427 ! IPO7_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0012428 ! IPO7_HUMAN-Phosphotyrosine311 [Term] id: CCO:B0005662 name: XPO2_HUMAN def: "Exportin-2" [UniProtKB:P55060] synonym: "Cellular apoptosis susceptibility protein" EXACT [UniProtKB:P55060] synonym: "Chromosome segregation 1-like protein" EXACT [UniProtKB:P55060] synonym: "Exp2" EXACT [UniProtKB:P55060] synonym: "Importin-alpha re-exporter" EXACT [UniProtKB:P55060] xref: EMBL:AAC35007.1 xref: EMBL:AAC35008.1 xref: EMBL:AAC35009.1 xref: EMBL:AAC35297.1 xref: EMBL:AAC50367.1 xref: EMBL:AAI08310.1 xref: EMBL:AAI09314.1 xref: EMBL:AAI09315.1 xref: EMBL:CAI19615.1 xref: EMBL:CAI42818.1 xref: UniProtKB:O75432 xref: UniProtKB:P55060 xref: UniProtKB:Q32M40 xref: UniProtKB:Q9H5B7 xref: UniProtKB:Q9NTS0 xref: UniProtKB:Q9UP98 xref: UniProtKB:Q9UP99 xref: UniProtKB:Q9UPA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005941 ! CSE1L_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001803 ! importin-alpha export receptor activity relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0006829 ! ran-xpot-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0008297 ! ppp5c-cse1l physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016562 ! ikbkg-cse1l physical interaction relationship: participates_in CCO:I0017054 ! tnfrsf1b-cse1l physical interaction relationship: participates_in CCO:I0017976 ! eif4e-importinalpha- physical interaction relationship: participates_in CCO:I0020151 ! rpl22-cse1l physical interaction relationship: participates_in CCO:I0020278 ! cse1l-hnrpl physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0014715 ! XPO2_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005663 name: TNPO1_HUMAN def: "Transportin-1" [UniProtKB:Q92973] synonym: "Importin beta-2" EXACT [UniProtKB:Q92973] synonym: "Karyopherin beta-2" EXACT [UniProtKB:Q92973] synonym: "M9 region interaction protein" EXACT [UniProtKB:Q92973] synonym: "MIP" EXACT [UniProtKB:Q92973] xref: EMBL:AAB58254.1 xref: EMBL:AAB68948.1 xref: EMBL:AAC50723.1 xref: EMBL:AAH40340.1 xref: UniProtKB:Q92957 xref: UniProtKB:Q92973 xref: UniProtKB:Q92975 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005801 ! TNPO1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001742 ! nuclear localization sequence binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006829 ! ran-xpot-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007310 ! ran-tnpo1-1 direct interaction [Term] id: CCO:B0005664 name: XPOT_HUMAN def: "Exportin-T" [UniProtKB:O43592] synonym: "Exportin(tRNA)" EXACT [UniProtKB:O43592] synonym: "tRNA exportin" EXACT [UniProtKB:O43592] xref: EMBL:AAC39793.1 xref: EMBL:AAH00950.1 xref: EMBL:AAH20569.1 xref: EMBL:CAA76202.1 xref: UniProtKB:A6NLH1 xref: UniProtKB:O43592 xref: UniProtKB:O43784 xref: UniProtKB:Q8WUG2 xref: UniProtKB:Q9BVS7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005943 ! XPOT_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006829 ! ran-xpot-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0016716 ! map3k3-xpot physical interaction relationship: participates_in CCO:I0017014 ! tnfrsf1a-xpot physical interaction [Term] id: CCO:B0005665 name: XPO7_HUMAN def: "Exportin-7" [UniProtKB:Q9UIA9] synonym: "Exp7" EXACT [UniProtKB:Q9UIA9] synonym: "Ran-binding protein 16" EXACT [UniProtKB:Q9UIA9] xref: EMBL:AAF21771.1 xref: EMBL:AAH14219.1 xref: EMBL:AAH30785.1 xref: EMBL:BAA34465.1 xref: UniProtKB:O94846 xref: UniProtKB:Q6PJK9 xref: UniProtKB:Q8NEK7 xref: UniProtKB:Q9UIA9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005942 ! XPO7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006829 ! ran-xpot-1 physical interaction relationship: participates_in CCO:I0016559 ! ikbkg-xpo7 physical interaction relationship: participates_in CCO:I0020364 ! mapk9-xpo7 physical interaction relationship: transforms_into CCO:B0014716 ! XPO7_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0071891 ! XPO7_HUMAN-Phosphotyrosine58 [Term] id: CCO:B0005666 name: SOS2_HUMAN def: "Son of sevenless homolog 2" [UniProtKB:Q07890] synonym: "SOS-2" EXACT [UniProtKB:Q07890] xref: EMBL:AAA35914.1 xref: EMBL:AAA91852.1 xref: UniProtKB:Q07890 xref: UniProtKB:Q15503 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005650 ! SOS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0006844 ! sos2-cd2ap-1 physical interaction relationship: participates_in CCO:I0017837 ! sos2-grb2-1 physical interaction relationship: participates_in CCO:I0017838 ! sos2-pacsin3-1 physical interaction relationship: participates_in CCO:I0017839 ! sos2-snx9-1 physical interaction relationship: participates_in CCO:I0017840 ! sos2-snag1-1 physical interaction relationship: participates_in CCO:I0019216 ! sos2-grb2-2 physical interaction relationship: participates_in CCO:I0019217 ! sos2-pacsin3-2 physical interaction relationship: participates_in CCO:I0019218 ! sos2-snx9-2 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0005667 name: ELOC_HUMAN def: "Transcription elongation factor B polypeptide 1" [UniProtKB:Q15369] synonym: "EloC" EXACT [UniProtKB:Q15369] synonym: "Elongin 15 kDa subunit" EXACT [UniProtKB:Q15369] synonym: "Elongin-C" EXACT [UniProtKB:Q15369] synonym: "RNA polymerase II transcription factor SIII subunit C" EXACT [UniProtKB:Q15369] synonym: "SIII p15" EXACT [UniProtKB:Q15369] xref: EMBL:AAA67650.1 xref: EMBL:AAH13809.1 xref: EMBL:AAH93065.1 xref: EMBL:AAI00029.1 xref: EMBL:AAI00284.1 xref: UniProtKB:Q15369 xref: UniProtKB:Q567Q6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004562 ! TCEB1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006845 ! tceb1-tceb2-vh1 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0015846 ! tceb1-tceb2 physical interaction relationship: participates_in CCO:I0016227 ! tceb1-tceb2-1 physical interaction relationship: participates_in CCO:I0016228 ! tceb1-tceb2-2 physical interaction relationship: participates_in CCO:I0018596 ! tceb1-med8-1 physical interaction relationship: participates_in CCO:I0019485 ! tceb1-tceb2-4 physical interaction relationship: participates_in CCO:I0019486 ! tceb1-tceb2-5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005668 name: ELOB_HUMAN def: "Transcription elongation factor B polypeptide 2" [UniProtKB:Q15370] synonym: "EloB" EXACT [UniProtKB:Q15370] synonym: "Elongin 18 kDa subunit" EXACT [UniProtKB:Q15370] synonym: "Elongin B" EXACT [UniProtKB:Q15370] synonym: "RNA polymerase II transcription factor SIII subunit B" EXACT [UniProtKB:Q15370] synonym: "SIII p18" EXACT [UniProtKB:Q15370] xref: EMBL:AAA75522.1 xref: EMBL:AAC08452.1 xref: EMBL:AAH13306.1 xref: EMBL:AAH65000.1 xref: UniProtKB:Q15370 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004561 ! TCEB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006845 ! tceb1-tceb2-vh1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0015846 ! tceb1-tceb2 physical interaction relationship: participates_in CCO:I0016227 ! tceb1-tceb2-1 physical interaction relationship: participates_in CCO:I0016228 ! tceb1-tceb2-2 physical interaction relationship: participates_in CCO:I0018595 ! tceb2-med8-1 physical interaction relationship: participates_in CCO:I0018597 ! tceb2-med8-2 physical interaction relationship: participates_in CCO:I0019485 ! tceb1-tceb2-4 physical interaction relationship: participates_in CCO:I0019486 ! tceb1-tceb2-5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011679 ! ELOB_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005669 name: ELMO1_HUMAN def: "Engulfment and cell motility protein 1" [UniProtKB:Q92556] synonym: "CED-12 homolog" EXACT [UniProtKB:Q92556] xref: EMBL:AAH03051.1 xref: EMBL:AAH64635.1 xref: EMBL:AAH77074.1 xref: EMBL:AAI14342.1 xref: EMBL:AAL14466.1 xref: EMBL:BAA13397.2 xref: EMBL:CAB66721.1 xref: UniProtKB:Q29R79 xref: UniProtKB:Q92556 xref: UniProtKB:Q96PB0 xref: UniProtKB:Q9H0I1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004560 ! ELMO1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006852 ! rhog-elmo1-1 physical interaction relationship: participates_in CCO:I0007074 ! rhog-elmo1-3 physical interaction relationship: participates_in CCO:I0007238 ! rhog-elmo1-2 physical interaction relationship: participates_in CCO:I0016218 ! hck-elmo1-1 physical interaction relationship: participates_in CCO:I0017843 ! hck-elmo1-3 physical interaction relationship: participates_in CCO:I0017851 ! elmo1-dock1-1 physical interaction relationship: participates_in CCO:I0017854 ! elmo1-dock1-2 physical interaction relationship: participates_in CCO:I0017855 ! elmo1-dock1-3 physical interaction relationship: participates_in CCO:I0017856 ! elmo1-dock1-4 physical interaction relationship: participates_in CCO:I0017860 ! elmo1-dock1-5 physical interaction relationship: participates_in CCO:I0018280 ! hck-elmo1-2 physical interaction relationship: participates_in CCO:I0018296 ! rac1-elmo1-1 physical interaction relationship: participates_in CCO:I0018297 ! rac1-dock-1 physical interaction relationship: participates_in CCO:I0018436 ! hck-elmo1-4 physical interaction relationship: participates_in CCO:P0001131 ! Rac protein signal transduction [Term] id: CCO:B0005670 name: GGA1_HUMAN def: "ADP-ribosylation factor-binding protein GGA1" [UniProtKB:Q9UJY5] synonym: "Gamma-adaptin-related protein 1" EXACT [UniProtKB:Q9UJY5] synonym: "Golgi-localized, gamma ear-containing, ARF-binding protein 1" EXACT [UniProtKB:Q9UJY5] xref: EMBL:AAF05707.1 xref: EMBL:AAF35393.1 xref: EMBL:AAF42847.1 xref: EMBL:AAH00538.2 xref: EMBL:BAC11501.1 xref: EMBL:CAB53679.1 xref: EMBL:CAI20369.1 xref: EMBL:CAI20951.1 xref: UniProtKB:Q5TG07 xref: UniProtKB:Q9BW94 xref: UniProtKB:Q9UG00 xref: UniProtKB:Q9UGW0 xref: UniProtKB:Q9UGW1 xref: UniProtKB:Q9UJY5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004696 ! GGA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017852 ! gga1-arf1-1 physical interaction relationship: participates_in CCO:I0017853 ! gga1-tsg101-1 physical interaction relationship: transforms_into CCO:B0011930 ! GGA1_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 [Term] id: CCO:B0005671 name: BIRC2_HUMAN def: "Baculoviral IAP repeat-containing protein 2" [UniProtKB:Q13490] synonym: "C-IAP1" EXACT [UniProtKB:Q13490] synonym: "HIAP-2" EXACT [UniProtKB:Q13490] synonym: "HIAP2" EXACT [UniProtKB:Q13490] synonym: "IAP homolog B" EXACT [UniProtKB:Q13490] synonym: "Inhibitor of apoptosis protein 2" EXACT [UniProtKB:Q13490] synonym: "RING finger protein 48" EXACT [UniProtKB:Q13490] synonym: "TNFR2-TRAF-signaling complex protein 2" EXACT [UniProtKB:Q13490] xref: EMBL:AAC41942.1 xref: EMBL:AAC50372.1 xref: EMBL:AAC50508.1 xref: EMBL:AAH16174.1 xref: EMBL:AAH28578.1 xref: EMBL:AAY46158.1 xref: UniProtKB:Q13490 xref: UniProtKB:Q16516 xref: UniProtKB:Q4TTG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004165 ! BIRC2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006858 ! tnf-tnfrsf1a-2 physical interaction relationship: participates_in CCO:I0014986 ! birc2-magea11 physical interaction relationship: participates_in CCO:I0015637 ! birc2-traf2 physical interaction relationship: participates_in CCO:I0015983 ! birc2-traf2-5 physical interaction relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0016259 ! birc2-casp7-1 physical interaction relationship: participates_in CCO:I0018314 ! tnf_r1-tradd-1 physical interaction relationship: participates_in CCO:I0018376 ! birc2-traf2-1 physical interaction relationship: participates_in CCO:I0018377 ! birc2-diablo-1 physical interaction relationship: participates_in CCO:I0018379 ! birc2-traf2-4 physical interaction relationship: participates_in CCO:I0018380 ! birc2-diablo-2 physical interaction relationship: participates_in CCO:I0018552 ! birc2-traf2-2 physical interaction relationship: participates_in CCO:I0018619 ! mihb-diablo physical interaction relationship: participates_in CCO:I0018788 ! birc2-casp7-2 physical interaction relationship: participates_in CCO:I0018789 ! birc2-casp3-3 physical interaction relationship: participates_in CCO:I0018797 ! tnf_r1-tradd physical interaction relationship: participates_in CCO:I0019248 ! birc2-casp9-1 physical interaction relationship: participates_in CCO:I0019301 ! birc2-traf2-3 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0005672 name: TRADD_HUMAN def: "Tumor necrosis factor receptor type 1-associated DEATH domain protein" [UniProtKB:Q15628] synonym: "TNFR1-associated DEATH domain protein" EXACT [UniProtKB:Q15628] synonym: "TNFRSF1A-associated via death domain" EXACT [UniProtKB:Q15628] xref: EMBL:AAA98482.1 xref: EMBL:AAH04491.1 xref: EMBL:AAP35580.1 xref: EMBL:AAS68637.1 xref: EMBL:AAX89407.1 xref: EMBL:CAC38018.2 xref: UniProtKB:Q15628 xref: UniProtKB:Q52NZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005821 ! TRADD_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004137 ! intermediate filament binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0006858 ! tnf-tnfrsf1a-2 physical interaction relationship: participates_in CCO:I0006859 ! tnf-tnfrsf1a-3 physical interaction relationship: participates_in CCO:I0006860 ! tnf-tnfrsf1a-4 physical interaction relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0016253 ! tradd-traf2-2 physical interaction relationship: participates_in CCO:I0017057 ! tradd-pdcd8 physical interaction relationship: participates_in CCO:I0017058 ! tradd-kpnb1 physical interaction relationship: participates_in CCO:I0017059 ! tradd-hspa1l physical interaction relationship: participates_in CCO:I0017060 ! tradd-hspa8 physical interaction relationship: participates_in CCO:I0017061 ! tradd-atp1a1 physical interaction relationship: participates_in CCO:I0017062 ! tradd-slc25a5 physical interaction relationship: participates_in CCO:I0017063 ! tradd-ipo8 physical interaction relationship: participates_in CCO:I0017064 ! tradd-rps3 physical interaction relationship: participates_in CCO:I0017065 ! tradd-dnaja1 physical interaction relationship: participates_in CCO:I0017066 ! tradd-c1qbp physical interaction relationship: participates_in CCO:I0017067 ! tradd-eef1a2 physical interaction relationship: participates_in CCO:I0017068 ! tradd-tradd physical interaction relationship: participates_in CCO:I0017069 ! tradd-cad physical interaction relationship: participates_in CCO:I0017070 ! tradd-actg1 physical interaction relationship: participates_in CCO:I0017071 ! tradd-slc25a3 physical interaction relationship: participates_in CCO:I0017072 ! tradd-lgals3bp physical interaction relationship: participates_in CCO:I0017073 ! tradd-nap1l1 physical interaction relationship: participates_in CCO:I0017074 ! tradd-cltc physical interaction relationship: participates_in CCO:I0017075 ! tradd-rcn2 physical interaction relationship: participates_in CCO:I0017076 ! tradd-hsp70_1 physical interaction relationship: participates_in CCO:I0017077 ! tradd-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0017078 ! tradd-ipo7 physical interaction relationship: participates_in CCO:I0017079 ! tradd-vim physical interaction relationship: participates_in CCO:I0017080 ! tradd-slc25a6 physical interaction relationship: participates_in CCO:I0017081 ! tradd-hspca physical interaction relationship: participates_in CCO:I0017082 ! tradd-prkdc physical interaction relationship: participates_in CCO:I0017083 ! tradd-tuba2 physical interaction relationship: participates_in CCO:I0017084 ! tradd-atp2a2 physical interaction relationship: participates_in CCO:I0017085 ! tradd-rps16 physical interaction relationship: participates_in CCO:I0017086 ! tradd-rps27 physical interaction relationship: participates_in CCO:I0017263 ! tradd-traf2 physical interaction relationship: participates_in CCO:I0017785 ! tradd-traf2-3 direct interaction relationship: participates_in CCO:I0018015 ! tnfrsf1a-tradd-1 physical interaction relationship: participates_in CCO:I0018314 ! tnf_r1-tradd-1 physical interaction relationship: participates_in CCO:I0018489 ! tnfrsf1a-tradd-6 physical interaction relationship: participates_in CCO:I0018490 ! tradd-tradd-2 physical interaction relationship: participates_in CCO:I0018612 ! tnfrsf1a-tradd-2 physical interaction relationship: participates_in CCO:I0018614 ! tradd-tradd-1 physical interaction relationship: participates_in CCO:I0018797 ! tnf_r1-tradd physical interaction relationship: participates_in CCO:I0019245 ! tnfrsf1a-tradd-7 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0005673 name: RIPK1_HUMAN def: "Receptor-interacting serine/threonine-protein kinase 1" [UniProtKB:Q13546] synonym: "Cell death protein RIP" EXACT [UniProtKB:Q13546] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13546] synonym: "Receptor-interacting protein" EXACT [UniProtKB:Q13546] synonym: "Serine/threonine-protein kinase RIP" EXACT [UniProtKB:Q13546] xref: EMBL:AAC32232.1 xref: EMBL:AAC50137.1 xref: EMBL:AAI26255.1 xref: EMBL:AAI26257.1 xref: EMBL:AAT74626.1 xref: EMBL:CAD70625.1 xref: UniProtKB:A0AV89 xref: UniProtKB:Q13180 xref: UniProtKB:Q13546 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005492 ! RIPK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006858 ! tnf-tnfrsf1a-2 physical interaction relationship: participates_in CCO:I0006859 ! tnf-tnfrsf1a-3 physical interaction relationship: participates_in CCO:I0006860 ! tnf-tnfrsf1a-4 physical interaction relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0016253 ! tradd-traf2-2 physical interaction relationship: participates_in CCO:I0016892 ! ripk1-hspa1l physical interaction relationship: participates_in CCO:I0016893 ! ripk1-hspa5 physical interaction relationship: participates_in CCO:I0016894 ! ripk1-hspa8 physical interaction relationship: participates_in CCO:I0016895 ! ripk1-slc25a5 physical interaction relationship: participates_in CCO:I0016896 ! ripk1-hspa9b physical interaction relationship: participates_in CCO:I0016897 ! ripk1-rpl23 physical interaction relationship: participates_in CCO:I0016898 ! ripk1-dnaja1 physical interaction relationship: participates_in CCO:I0016899 ! ripk1-ripk1 physical interaction relationship: participates_in CCO:I0016900 ! ripk1-cad physical interaction relationship: participates_in CCO:I0016901 ! ripk1-actg1 physical interaction relationship: participates_in CCO:I0016902 ! ripk1-rcn2 physical interaction relationship: participates_in CCO:I0016903 ! ripk1-hsp70_1 physical interaction relationship: participates_in CCO:I0016904 ! ripk1-hspca physical interaction relationship: participates_in CCO:I0016905 ! ripk1-tuba2 physical interaction relationship: participates_in CCO:I0018019 ! tnsfrsf6-ripk1-1 physical interaction relationship: participates_in CCO:I0018613 ! casp8-ripk1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0013875 ! RIPK1_HUMAN-Phosphotyrosine384 relationship: transforms_into CCO:B0013876 ! RIPK1_HUMAN-Phosphotyrosine387 relationship: transforms_into CCO:B0013877 ! RIPK1_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0070058 ! RIPK1_HUMAN-Phosphoserine320 [Term] id: CCO:B0005674 name: E2AK1_HUMAN def: "Eukaryotic translation initiation factor 2-alpha kinase 1" [UniProtKB:Q9BQI3] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9BQI3] synonym: "HCR" EXACT [UniProtKB:Q9BQI3] synonym: "Heme-controlled repressor" EXACT [UniProtKB:Q9BQI3] synonym: "Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase" EXACT [UniProtKB:Q9BQI3] synonym: "Heme-regulated inhibitor" EXACT [UniProtKB:Q9BQI3] synonym: "Hemin-sensitive initiation factor 2-alpha kinase" EXACT [UniProtKB:Q9BQI3] xref: EMBL:AAF18391.1 xref: EMBL:AAF66736.1 xref: EMBL:AAF70289.1 xref: EMBL:AAF71057.1 xref: EMBL:AAG09683.1 xref: EMBL:AAH06524.1 xref: EMBL:BAA92607.1 xref: EMBL:BAC11461.1 xref: EMBL:CAB66498.1 xref: EMBL:CAD39152.1 xref: UniProtKB:Q8NBW3 xref: UniProtKB:Q9BQI3 xref: UniProtKB:Q9HC02 xref: UniProtKB:Q9NYE0 xref: UniProtKB:Q9P0V6 xref: UniProtKB:Q9P1J5 xref: UniProtKB:Q9P2H8 xref: UniProtKB:Q9UHG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004530 ! EIF2AK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006872 ! eif2ak1-cdc37-8 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002664 ! negative regulation of translational initiation by iron relationship: participates_in CCO:P0002753 ! negative regulation of hemoglobin biosynthetic process relationship: transforms_into CCO:B0011606 ! E2AK1_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0011607 ! E2AK1_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0011608 ! E2AK1_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0011609 ! E2AK1_HUMAN-Phosphoserine278 relationship: transforms_into CCO:B0011610 ! E2AK1_HUMAN-Phosphothreonine488 [Term] id: CCO:B0005675 name: HIPK1_HUMAN def: "Homeodomain-interacting protein kinase 1" [UniProtKB:Q86Z02] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q86Z02] xref: EMBL:AAH28408.1 xref: EMBL:AAH33012.1 xref: EMBL:AAH36057.1 xref: EMBL:BAA31605.1 xref: EMBL:BAC57075.1 xref: EMBL:CAD38689.1 xref: EMBL:EAW56590.1 xref: UniProtKB:A6NJ34 xref: UniProtKB:O75125 xref: UniProtKB:Q86Z02 xref: UniProtKB:Q8IYD7 xref: UniProtKB:Q8NDN5 xref: UniProtKB:Q8NEB6 xref: UniProtKB:Q8TBZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004808 ! HIPK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006873 ! tp53-hipk1-2 physical interaction relationship: participates_in CCO:I0007434 ! tp53-hipk1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012196 ! HIPK1_HUMAN-Phosphotyrosine352 [Term] id: CCO:B0005676 name: BAP31_HUMAN def: "B-cell receptor-associated protein 31" [UniProtKB:P51572] synonym: "6C6-AG tumor-associated antigen" EXACT [UniProtKB:P51572] synonym: "BCR-associated protein Bap31" EXACT [UniProtKB:P51572] synonym: "p28 Bap31" EXACT [UniProtKB:P51572] synonym: "Protein CDM" EXACT [UniProtKB:P51572] xref: EMBL:AAA79508.1 xref: EMBL:AAH14323.1 xref: EMBL:AAH65292.1 xref: EMBL:CAA57015.1 xref: EMBL:CAA57415.1 xref: EMBL:CAA83501.1 xref: UniProtKB:P51572 xref: UniProtKB:Q13836 xref: UniProtKB:Q96CF0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004137 ! BCAP31_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001534 ! ER-Golgi intermediate compartment membrane relationship: participates_in CCO:I0006883 ! bcl2-bcap31 physical interaction relationship: participates_in CCO:I0007132 ! bcap31-bcl2 physical interaction relationship: participates_in CCO:I0018205 ! bcl2l1-bcap31 physical interaction relationship: participates_in CCO:I0018206 ! casp8-bcap31 physical interaction [Term] id: CCO:B0005677 name: BNIP2_HUMAN def: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 2" [UniProtKB:Q12982] xref: EMBL:AAC00021.1 xref: EMBL:AAH02461.1 xref: EMBL:AAP03429.1 xref: UniProtKB:Q12982 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004177 ! BNIP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006885 ! bcl_2-nip2-1 physical interaction relationship: participates_in CCO:I0015815 ! bnip2-creb3 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0043213 ! BNIP2_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0043214 ! BNIP2_HUMAN-Phosphothreonine116 [Term] id: CCO:B0005678 name: BNIP3_HUMAN def: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3" [UniProtKB:Q12983] xref: EMBL:AAC00022.1 xref: EMBL:AAC16738.1 xref: EMBL:AAH21989.1 xref: EMBL:AAW62256.1 xref: EMBL:CAD13201.1 xref: UniProtKB:O14620 xref: UniProtKB:Q12983 xref: UniProtKB:Q96GP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004178 ! BNIP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006886 ! bcl_2-nip3-1 physical interaction relationship: participates_in CCO:I0015502 ! bnip3-tmem11 physical interaction relationship: participates_in CCO:I0015568 ! bnip3-bnip3l physical interaction relationship: participates_in CCO:I0015822 ! bnip3-bnip3 physical interaction relationship: participates_in CCO:I0018363 ! nip3-nip3-1 physical interaction relationship: participates_in CCO:I0019424 ! tmem11-bnip3 physical interaction relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000841 ! negative regulation of survival gene product expression relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0010821 ! BNIP3_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0010822 ! BNIP3_HUMAN-Phosphoserine95 [Term] id: CCO:B0005679 name: IF4A1_HUMAN def: "Eukaryotic initiation factor 4A-I" [UniProtKB:P60842] synonym: "ATP-dependent RNA helicase eIF4A-1" EXACT [UniProtKB:P60842] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P60842] synonym: "eIF-4A-I" EXACT [UniProtKB:P60842] synonym: "eIF4A-I" EXACT [UniProtKB:P60842] xref: EMBL:AAH09585.1 xref: EMBL:AAH73752.1 xref: EMBL:AAV38683.1 xref: EMBL:AAV38684.1 xref: EMBL:BAA02897.1 xref: UniProtKB:P04765 xref: UniProtKB:P60842 xref: UniProtKB:Q5U018 xref: UniProtKB:Q61516 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004862 ! EIF4A1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000071 ! RNA cap binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0006888 ! eif4g2-eif4a1-1 direct interaction relationship: participates_in CCO:I0007603 ! eif4g2-eif4a1-2 direct interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016285 ! eif4g1-eif4a1-3 physical interaction relationship: participates_in CCO:I0018568 ! eif4g1-eif4a1-2 physical interaction relationship: participates_in CCO:I0018570 ! eif4g1-eif4a1-1 physical interaction relationship: transforms_into CCO:B0067022 ! IF4A1_HUMAN-Phosphothreonine158 [Term] id: CCO:B0005680 name: AP2B_HUMAN def: "Transcription factor AP-2 beta" [UniProtKB:Q92481] synonym: "Activating enhancer-binding protein 2 beta" EXACT [UniProtKB:Q92481] synonym: "AP2-beta" EXACT [UniProtKB:Q92481] xref: EMBL:AAH37225.1 xref: EMBL:CAA64990.1 xref: EMBL:CAA71047.1 xref: EMBL:CAB41305.1 xref: EMBL:CAB89563.3 xref: EMBL:CAC01130.1 xref: EMBL:CAI20235.2 xref: UniProtKB:Q5JYX6 xref: UniProtKB:Q92481 xref: UniProtKB:Q9NQ63 xref: UniProtKB:Q9NU99 xref: UniProtKB:Q9UJI7 xref: UniProtKB:Q9Y214 xref: UniProtKB:Q9Y3K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004074 ! TFAP2B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006892 ! cited2-tfap2b-1 physical interaction relationship: participates_in CCO:I0007919 ! ap2b-ubc9-1 physical interaction relationship: participates_in CCO:I0007922 ! ubc9-ap2b-1 physical interaction relationship: participates_in CCO:I0020571 ! hist1h2ac-tfap2b physical interaction relationship: participates_in CCO:I0020685 ! vps11-tfap2b physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002565 ! positive regulation of transcription from RNA polymerase II promoter, global relationship: transforms_into CCO:B0010565 ! AP2B_HUMAN-Phosphoserine258 [Term] id: CCO:B0005681 name: CREB1_HUMAN def: "cAMP response element-binding protein" [UniProtKB:P16220] synonym: "CREB" EXACT [UniProtKB:P16220] xref: EMBL:AAA35715.1 xref: EMBL:AAA35716.1 xref: EMBL:AAA35717.1 xref: EMBL:AAB20597.1 xref: EMBL:AAD13869.1 xref: EMBL:AAH10636.1 xref: EMBL:CAA39151.1 xref: EMBL:CAA42620.1 xref: UniProtKB:P16220 xref: UniProtKB:P21934 xref: UniProtKB:Q9UMA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004395 ! CREB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006907 ! atr-creb1-1 phosphorylation relationship: participates_in CCO:I0018693 ! rps6ka1-creb1-1 phosphorylation relationship: participates_in CCO:I0018762 ! tssk4-creb1-2 physical interaction relationship: participates_in CCO:I0019212 ! tssk4-creb1-1 physical interaction relationship: participates_in CCO:I0019213 ! tssk4-creb1-3 physical interaction relationship: participates_in CCO:I0019214 ! tssk4-creb1-4 phosphorylation relationship: participates_in CCO:I0019579 ! creb1-chd3 physical interaction relationship: participates_in CCO:I0019697 ! creb1-vim physical interaction relationship: participates_in CCO:I0019959 ! creb1-c14orf1 physical interaction relationship: participates_in CCO:I0020145 ! recql5-creb1 physical interaction relationship: participates_in CCO:I0020421 ! rab1a-creb1 physical interaction relationship: participates_in CCO:I0020533 ! creb1-hps6 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0011345 ! CREB1_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0011346 ! CREB1_HUMAN-Phosphothreonine119 relationship: transforms_into CCO:B0011347 ! CREB1_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0011348 ! CREB1_HUMAN-Phosphoserine142 [Term] id: CCO:B0005682 name: CENPH_HUMAN def: "Centromere protein H" [UniProtKB:Q9H3R5] synonym: "CENP-H" EXACT [UniProtKB:Q9H3R5] synonym: "Interphase centromere complex protein 35" EXACT [UniProtKB:Q9H3R5] xref: EMBL:AAH12024.1 xref: EMBL:AAH15355.1 xref: EMBL:BAB18635.1 xref: UniProtKB:Q9H3R5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004326 ! CENPH_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005864 ! kinetochore binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0006909 ! cenph_kntc2_2 physical interaction relationship: participates_in CCO:I0006910 ! cenph_kntc2_4 physical interaction relationship: participates_in CCO:I0007456 ! cenph_kntc2_1 physical interaction [Term] id: CCO:B0005683 name: EDC4_HUMAN def: "Enhancer of mRNA-decapping protein 4" [UniProtKB:Q6P2E9] synonym: "Autoantigen Ge-1" EXACT [UniProtKB:Q6P2E9] synonym: "Autoantigen RCD-8" EXACT [UniProtKB:Q6P2E9] synonym: "Hedls" EXACT [UniProtKB:Q6P2E9] synonym: "Human enhancer of decapping large subunit" EXACT [UniProtKB:Q6P2E9] xref: EMBL:AAA21833.1 xref: EMBL:AAB51444.1 xref: EMBL:AAH43616.1 xref: EMBL:AAH53598.1 xref: EMBL:AAH64567.1 xref: EMBL:BAC87512.1 xref: UniProtKB:Q13025 xref: UniProtKB:Q13826 xref: UniProtKB:Q6P2E9 xref: UniProtKB:Q6ZR12 xref: UniProtKB:Q7Z6H7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004543 ! EDC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006911 ! dcp1a-rcd8-xrn1 colocalization relationship: participates_in CCO:I0007016 ! upf1-rcd8 physical interaction relationship: participates_in CCO:I0018111 ! zfp36-rcd8-1 physical interaction relationship: transforms_into CCO:B0011625 ! EDC4_HUMAN-Phosphothreonine693 relationship: transforms_into CCO:B0011626 ! EDC4_HUMAN-Phosphoserine729 relationship: transforms_into CCO:B0011627 ! EDC4_HUMAN-Phosphoserine741 relationship: transforms_into CCO:B0011628 ! EDC4_HUMAN-Phosphoserine844 relationship: transforms_into CCO:B0011629 ! EDC4_HUMAN-Phosphoserine875 relationship: transforms_into CCO:B0011630 ! EDC4_HUMAN-Phosphoserine879 relationship: transforms_into CCO:B0011631 ! EDC4_HUMAN-Phosphoserine887 relationship: transforms_into CCO:B0011632 ! EDC4_HUMAN-Phosphoserine1067 relationship: transforms_into CCO:B0011633 ! EDC4_HUMAN-Phosphothreonine1072 relationship: transforms_into CCO:B0048248 ! EDC4_HUMAN-Phosphoserine723 relationship: transforms_into CCO:B0048249 ! EDC4_HUMAN-Phosphoserine725 relationship: transforms_into CCO:B0048250 ! EDC4_HUMAN-Phosphothreonine727 relationship: transforms_into CCO:B0048251 ! EDC4_HUMAN-Phosphoserine734 relationship: transforms_into CCO:B0064920 ! EDC4_HUMAN-Phosphoserine809 relationship: transforms_into CCO:B0064921 ! EDC4_HUMAN-Phosphothreonine821 [Term] id: CCO:B0005684 name: PLAK_HUMAN def: "Junction plakoglobin" [UniProtKB:P14923] synonym: "Catenin gamma" EXACT [UniProtKB:P14923] synonym: "Desmoplakin III" EXACT [UniProtKB:P14923] synonym: "Desmoplakin-3" EXACT [UniProtKB:P14923] xref: EMBL:AAA64895.1 xref: EMBL:AAG16727.1 xref: EMBL:AAH00441.2 xref: EMBL:AAH11865.1 xref: EMBL:AAO85780.1 xref: EMBL:CAA92522.1 xref: EMBL:CAC04246.1 xref: EMBL:EAW60762.1 xref: UniProtKB:P14923 xref: UniProtKB:Q15093 xref: UniProtKB:Q15151 xref: UniProtKB:Q7L3S5 xref: UniProtKB:Q86W21 xref: UniProtKB:Q9BWC4 xref: UniProtKB:Q9HCX9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005331 ! JUP_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006912 ! tcf7l2-ctnnb1-2 physical interaction relationship: participates_in CCO:I0007011 ! tcf7l2-ctnnb1 physical interaction relationship: participates_in CCO:I0007700 ! ctnnb1-tcf7l2-3 physical interaction relationship: participates_in CCO:I0007701 ! ctnnb1-tcf7l2-4 physical interaction relationship: participates_in CCO:I0007702 ! ctnnb1-tcf7l2-5 physical interaction relationship: participates_in CCO:I0007703 ! ctnnb1-tcf7l2-6 physical interaction relationship: participates_in CCO:I0007705 ! tcf7l2-ctnnb1-3 physical interaction relationship: participates_in CCO:I0007706 ! jup-psen1-7 physical interaction relationship: participates_in CCO:I0007803 ! tcf7l2-ctnnb1-1 physical interaction relationship: participates_in CCO:I0007804 ! tcf7l2-ctnnb1-5 physical interaction relationship: participates_in CCO:I0007805 ! tcf7l2-ctnnb1-6 physical interaction relationship: participates_in CCO:I0007806 ! jup-tcf7l2 physical interaction relationship: participates_in CCO:I0007807 ! jup-psen1-5 physical interaction relationship: participates_in CCO:I0018096 ! jup-psen1-1 physical interaction relationship: participates_in CCO:I0019310 ! jup-psen1 physical interaction relationship: participates_in CCO:I0019311 ! jup-psen1-2 physical interaction relationship: participates_in CCO:I0019897 ! arhgdia-jup physical interaction relationship: transforms_into CCO:B0013553 ! PLAK_HUMAN-Phosphotyrosine20 relationship: transforms_into CCO:B0013554 ! PLAK_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0069381 ! PLAK_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: transforms_into CCO:B0069383 ! PLAK_HUMAN-Phosphoserine665 [Term] id: CCO:B0005685 name: ABL2_HUMAN def: "Tyrosine-protein kinase ABL2" [UniProtKB:P42684] synonym: "Abelson murine leukemia viral oncogene homolog 2" EXACT [UniProtKB:P42684] synonym: "Abelson-related gene protein" EXACT [UniProtKB:P42684] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P42684] synonym: "Tyrosine kinase ARG" EXACT [UniProtKB:P42684] xref: EMBL:AAA35553.1 xref: EMBL:AAH65912.1 xref: EMBL:CAD98092.1 xref: EMBL:CAH70921.1 xref: EMBL:CAH70925.1 xref: EMBL:CAI13566.1 xref: EMBL:CAI13570.1 xref: EMBL:CAI15584.1 xref: EMBL:CAI15585.1 xref: UniProtKB:P42684 xref: UniProtKB:Q5T0X6 xref: UniProtKB:Q5W0C5 xref: UniProtKB:Q6NZY6 xref: UniProtKB:Q7Z301 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004014 ! ABL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006924 ! abl2-rin1-5 physical interaction relationship: participates_in CCO:I0007170 ! abl2-rin1-4 physical interaction relationship: participates_in CCO:I0017959 ! abl2-rin1-2 physical interaction relationship: participates_in CCO:I0018258 ! abl2-rin1-1 physical interaction relationship: participates_in CCO:I0018259 ! abl2-rin1-3 physical interaction relationship: participates_in CCO:I0018754 ! abl2-crk-2 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010412 ! ABL2_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0010413 ! ABL2_HUMAN-Phosphotyrosine231 relationship: transforms_into CCO:B0010414 ! ABL2_HUMAN-Phosphotyrosine272 relationship: transforms_into CCO:B0010415 ! ABL2_HUMAN-Phosphotyrosine299 relationship: transforms_into CCO:B0010416 ! ABL2_HUMAN-Phosphotyrosine303 relationship: transforms_into CCO:B0010417 ! ABL2_HUMAN-Phosphotyrosine310 relationship: transforms_into CCO:B0010418 ! ABL2_HUMAN-Phosphotyrosine439 relationship: transforms_into CCO:B0010419 ! ABL2_HUMAN-Phosphothreonine440 relationship: transforms_into CCO:B0010420 ! ABL2_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0010421 ! ABL2_HUMAN-Phosphotyrosine515 relationship: transforms_into CCO:B0010422 ! ABL2_HUMAN-Phosphoserine631 relationship: transforms_into CCO:B0010423 ! ABL2_HUMAN-Phosphoserine783 relationship: transforms_into CCO:B0010424 ! ABL2_HUMAN-Phosphoserine817 relationship: transforms_into CCO:B0010425 ! ABL2_HUMAN-Phosphoserine820 relationship: transforms_into CCO:B0010426 ! ABL2_HUMAN-Phosphoserine936 relationship: transforms_into CCO:B0052274 ! ABL2_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0065278 ! ABL2_HUMAN-Phosphoserine620 relationship: transforms_into CCO:B0065279 ! ABL2_HUMAN-Phosphoserine633 relationship: transforms_into CCO:B0065280 ! ABL2_HUMAN-Phosphoserine655 relationship: transforms_into CCO:B0065281 ! ABL2_HUMAN-Phosphoserine915 [Term] id: CCO:B0005686 name: HNRPD_HUMAN def: "Heterogeneous nuclear ribonucleoprotein D0" [UniProtKB:Q14103] synonym: "AU-rich element RNA-binding protein 1" EXACT [UniProtKB:Q14103] synonym: "hnRNP D0" EXACT [UniProtKB:Q14103] xref: EMBL:AAA35781.1 xref: EMBL:AAB96683.1 xref: EMBL:AAC23474.1 xref: EMBL:AAC23475.1 xref: EMBL:AAC23476.1 xref: EMBL:AAH02401.1 xref: EMBL:AAH23977.1 xref: EMBL:AAH26015.1 xref: EMBL:AAY40913.1 xref: EMBL:BAA09522.1 xref: EMBL:BAA09523.1 xref: EMBL:BAA09524.1 xref: EMBL:BAA09525.1 xref: EMBL:CAA27544.1 xref: UniProtKB:P07029 xref: UniProtKB:Q01858 xref: UniProtKB:Q14100 xref: UniProtKB:Q14101 xref: UniProtKB:Q14102 xref: UniProtKB:Q14103 xref: UniProtKB:Q4W5A1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014352 ! HNRNPD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006928 ! hnrpd-ube2i-2 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007823 ! hnrpd-ube2i physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012222 ! HNRPD_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0012223 ! HNRPD_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0012224 ! HNRPD_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0012225 ! HNRPD_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0012226 ! HNRPD_HUMAN-Phosphothreonine91 relationship: transforms_into CCO:B0012227 ! HNRPD_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0012228 ! HNRPD_HUMAN-Phosphothreonine193 relationship: transforms_into CCO:B0012229 ! HNRPD_HUMAN-Omega-N-methylated arginine345 [Term] id: CCO:B0005687 name: GRWD1_HUMAN def: "Glutamate-rich WD repeat-containing protein 1" [UniProtKB:Q9BQ67] xref: EMBL:AAH02440.1 xref: EMBL:AAK17998.1 xref: EMBL:BAB85528.1 xref: UniProtKB:Q8TF59 xref: UniProtKB:Q9BQ67 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004733 ! GRWD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008530 ! l2dtl-ddb1 physical interaction relationship: transforms_into CCO:B0011988 ! GRWD1_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0011989 ! GRWD1_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0048272 ! GRWD1_HUMAN-Phosphothreonine10 [Term] id: CCO:B0005688 name: WDR82_HUMAN def: "WD repeat-containing protein 82" [UniProtKB:Q6UXN9] synonym: "Swd2" EXACT [UniProtKB:Q6UXN9] xref: EMBL:AAQ88631.1 xref: EMBL:BAB85039.1 xref: UniProtKB:Q6UXN9 xref: UniProtKB:Q8TEB2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005928 ! WDR82_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: transforms_into CCO:B0014688 ! WDR82_HUMAN-Phosphoserine154 [Term] id: CCO:B0005689 name: WDR26_HUMAN def: "WD repeat-containing protein 26" [UniProtKB:Q9H7D7] synonym: "CUL4- and DDB1-associated WDR protein 2" EXACT [UniProtKB:Q9H7D7] synonym: "Myocardial ischemic preconditioning up-regulated protein 2" EXACT [UniProtKB:Q9H7D7] xref: EMBL:AAG35477.1 xref: EMBL:AAH31471.2 xref: EMBL:AAH34498.1 xref: EMBL:AAH52301.2 xref: EMBL:AAH63817.1 xref: EMBL:AAO67709.1 xref: EMBL:AAQ74770.1 xref: EMBL:ABK41102.1 xref: EMBL:BAB14955.1 xref: EMBL:BAD93124.1 xref: UniProtKB:A0MNN3 xref: UniProtKB:Q4G100 xref: UniProtKB:Q59EC4 xref: UniProtKB:Q5GLZ9 xref: UniProtKB:Q86UY4 xref: UniProtKB:Q9H3C2 xref: UniProtKB:Q9H7D7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005917 ! WDR26_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0008532 ! wdr26-ddb1 physical interaction relationship: transforms_into CCO:B0014673 ! WDR26_HUMAN-Phosphoserine121 [Term] id: CCO:B0005690 name: TLE3_HUMAN def: "Transducin-like enhancer protein 3" [UniProtKB:Q04726] synonym: "ESG3" EXACT [UniProtKB:Q04726] xref: EMBL:AAA61194.1 xref: EMBL:AAH41831.1 xref: EMBL:BAB13373.1 xref: UniProtKB:Q04726 xref: UniProtKB:Q8IVV6 xref: UniProtKB:Q8WVR2 xref: UniProtKB:Q9HCM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005790 ! TLE3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0014397 ! TLE3_HUMAN-Phosphoserine201 relationship: transforms_into CCO:B0014398 ! TLE3_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0014399 ! TLE3_HUMAN-Phosphoserine207 relationship: transforms_into CCO:B0014400 ! TLE3_HUMAN-Phosphoserine217 relationship: transforms_into CCO:B0014401 ! TLE3_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0014402 ! TLE3_HUMAN-Phosphoserine245 relationship: transforms_into CCO:B0014403 ! TLE3_HUMAN-Phosphothreonine259 relationship: transforms_into CCO:B0014404 ! TLE3_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0014405 ! TLE3_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0014406 ! TLE3_HUMAN-Phosphoserine286 relationship: transforms_into CCO:B0014407 ! TLE3_HUMAN-Phosphothreonine328 relationship: transforms_into CCO:B0014408 ! TLE3_HUMAN-Phosphothreonine334 relationship: transforms_into CCO:B0036038 ! TLE3_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0036039 ! TLE3_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0048413 ! TLE3_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0071413 ! TLE3_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0071414 ! TLE3_HUMAN-Phosphothreonine312 relationship: transforms_into CCO:B0071415 ! TLE3_HUMAN-Phosphothreonine319 relationship: transforms_into CCO:B0071416 ! TLE3_HUMAN-Phosphothreonine321 relationship: transforms_into CCO:B0071417 ! TLE3_HUMAN-Phosphoserine413 [Term] id: CCO:B0005691 name: SMU1_HUMAN def: "WD40 repeat-containing protein SMU1" [UniProtKB:Q2TAY7] synonym: "Smu-1 suppressor of mec-8 and unc-52 protein homolog" EXACT [UniProtKB:Q2TAY7] xref: EMBL:AAH02876.1 xref: EMBL:AAI10655.1 xref: EMBL:BAA91822.1 xref: EMBL:BAB13956.1 xref: EMBL:CAI15554.1 xref: UniProtKB:Q2TAY7 xref: UniProtKB:Q9BU59 xref: UniProtKB:Q9HA96 xref: UniProtKB:Q9NVD1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005640 ! SMU1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006931 ! cul4b-ddb1 physical interaction relationship: transforms_into CCO:B0070675 ! SMU1_HUMAN-N-acetylserine2 [Term] id: CCO:B0005692 name: CAC1C_HUMAN def: "Voltage-dependent L-type calcium channel subunit alpha-1C" [UniProtKB:Q13936] synonym: "Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle" EXACT [UniProtKB:Q13936] synonym: "Voltage-gated calcium channel subunit alpha Cav1.2" EXACT [UniProtKB:Q13936] xref: EMBL:AAA02500.2 xref: EMBL:AAA02501.1 xref: EMBL:AAA17030.1 xref: EMBL:AAA51899.1 xref: EMBL:AAA51900.1 xref: EMBL:AAA51901.1 xref: EMBL:AAA58409.1 xref: EMBL:AAA62832.1 xref: EMBL:AAA74590.1 xref: EMBL:AAB59461.1 xref: EMBL:AAI46847.1 xref: EMBL:AAM70049.1 xref: EMBL:AAT02226.1 xref: EMBL:AAX37354.1 xref: EMBL:AAX37355.1 xref: EMBL:AAX37356.1 xref: EMBL:CAA12174.1 xref: EMBL:CAA81218.1 xref: EMBL:CAA81219.1 xref: EMBL:CAA84340.1 xref: EMBL:CAA84341.1 xref: EMBL:CAA84342.1 xref: EMBL:CAA84343.1 xref: EMBL:CAA84344.1 xref: EMBL:CAA84345.1 xref: EMBL:CAA84346.1 xref: EMBL:CAA84347.1 xref: EMBL:CAA84348.1 xref: EMBL:CAA84349.1 xref: EMBL:CAA84350.1 xref: EMBL:CAA84351.1 xref: EMBL:CAA84352.1 xref: EMBL:CAA84353.1 xref: EMBL:CAA99284.1 xref: UniProtKB:B2RUT3 xref: UniProtKB:Q13917 xref: UniProtKB:Q13918 xref: UniProtKB:Q13919 xref: UniProtKB:Q13920 xref: UniProtKB:Q13921 xref: UniProtKB:Q13922 xref: UniProtKB:Q13923 xref: UniProtKB:Q13924 xref: UniProtKB:Q13925 xref: UniProtKB:Q13926 xref: UniProtKB:Q13927 xref: UniProtKB:Q13928 xref: UniProtKB:Q13929 xref: UniProtKB:Q13930 xref: UniProtKB:Q13932 xref: UniProtKB:Q13933 xref: UniProtKB:Q13936 xref: UniProtKB:Q14743 xref: UniProtKB:Q14744 xref: UniProtKB:Q15877 xref: UniProtKB:Q4VMI7 xref: UniProtKB:Q4VMI8 xref: UniProtKB:Q4VMI9 xref: UniProtKB:Q6PKM7 xref: UniProtKB:Q8N6C0 xref: UniProtKB:Q99025 xref: UniProtKB:Q99241 xref: UniProtKB:Q99875 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004206 ! CACNA1C_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001513 ! voltage-gated calcium channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0002727 ! dihydropyridine-sensitive calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000448 ! voltage-gated calcium channel complex relationship: located_in CCO:C0000740 ! postsynaptic density relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006932 ! cacna1c-cam-1 physical interaction relationship: participates_in CCO:I0006933 ! cacna1c-cam-2 physical interaction relationship: transforms_into CCO:B0010879 ! CAC1C_HUMAN-Phosphoserine815 relationship: transforms_into CCO:B0010880 ! CAC1C_HUMAN-Phosphoserine1535 relationship: transforms_into CCO:B0010881 ! CAC1C_HUMAN-Phosphoserine1973 relationship: transforms_into CCO:B0010882 ! CAC1C_HUMAN-Phosphoserine1981 [Term] id: CCO:B0005693 name: ARI4A_HUMAN def: "AT-rich interactive domain-containing protein 4A" [UniProtKB:P29374] synonym: "ARID domain-containing protein 4A" EXACT [UniProtKB:P29374] synonym: "RBBP-1" EXACT [UniProtKB:P29374] synonym: "Retinoblastoma-binding protein 1" EXACT [UniProtKB:P29374] xref: EMBL:AAB25833.1 xref: EMBL:AAB25834.1 xref: EMBL:AAB25835.2 xref: EMBL:AAB28543.1 xref: UniProtKB:P29374 xref: UniProtKB:Q15991 xref: UniProtKB:Q15992 xref: UniProtKB:Q15993 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004093 ! ARID4A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006936 ! brms1-arid4a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010602 ! ARI4A_HUMAN-Phosphoserine1109 [Term] id: CCO:B0005694 name: SDS3_HUMAN def: "Sin3 histone deacetylase corepressor complex component SDS3" [UniProtKB:Q9H7L9] synonym: "45 kDa Sin3-associated polypeptide" EXACT [UniProtKB:Q9H7L9] synonym: "Suppressor of defective silencing 3 protein homolog" EXACT [UniProtKB:Q9H7L9] xref: EMBL:AAH30252.1 xref: EMBL:AAH98404.1 xref: EMBL:BAB14685.1 xref: EMBL:BAB15750.1 xref: UniProtKB:Q4KMQ5 xref: UniProtKB:Q8N6H0 xref: UniProtKB:Q9H7L9 xref: UniProtKB:Q9H8D2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005577 ! SUDS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006937 ! brms1-sds3 physical interaction relationship: participates_in CCO:I0007097 ! hcfc1-sds3-1 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007719 ! sds3-brms1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0013982 ! SDS3_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0013983 ! SDS3_HUMAN-Phosphothreonine49 relationship: transforms_into CCO:B0013984 ! SDS3_HUMAN-Phosphothreonine55 relationship: transforms_into CCO:B0013985 ! SDS3_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0013986 ! SDS3_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0013987 ! SDS3_HUMAN-Phosphothreonine244 relationship: transforms_into CCO:B0048389 ! SDS3_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0070368 ! SDS3_HUMAN-Phosphoserine237 [Term] id: CCO:B0005695 name: NMI_HUMAN def: "N-myc-interactor" [UniProtKB:Q13287] synonym: "N-myc and STAT interactor" EXACT [UniProtKB:Q13287] synonym: "Nmi" EXACT [UniProtKB:Q13287] xref: EMBL:AAC12949.1 xref: EMBL:AAH01268.1 xref: EMBL:AAY15066.1 xref: UniProtKB:Q13287 xref: UniProtKB:Q53TI8 xref: UniProtKB:Q9BVE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005199 ! NMI_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006940 ! brms1-nmi physical interaction relationship: participates_in CCO:I0007046 ! nmi-stat5b-1 physical interaction relationship: participates_in CCO:I0007047 ! stat5b-nmi-2 physical interaction relationship: participates_in CCO:I0007048 ! nmi-stat5b-2 physical interaction relationship: participates_in CCO:I0007049 ! nmi-stat5b-3 physical interaction relationship: participates_in CCO:I0007050 ! nmi-stat1-1 physical interaction relationship: participates_in CCO:I0007053 ! nmi-stat5a-1 physical interaction relationship: participates_in CCO:I0007184 ! stat5b-nmi-3 physical interaction relationship: participates_in CCO:I0007185 ! cbp-stat5a-1 physical interaction relationship: participates_in CCO:I0007186 ! cbp-stat5b-1 physical interaction relationship: participates_in CCO:I0007515 ! stat5b-nmi-1 physical interaction relationship: participates_in CCO:I0007718 ! stat5b-nmi-4 physical interaction relationship: participates_in CCO:I0007721 ! nmi-brms1 physical interaction relationship: participates_in CCO:I0007969 ! myc-nmi-1 physical interaction relationship: participates_in CCO:I0008681 ! nmi-psma1 physical interaction relationship: participates_in CCO:I0015290 ! hgs-nmi physical interaction relationship: participates_in CCO:I0015450 ! gcsh-nmi physical interaction relationship: participates_in CCO:I0015546 ! hddc3-nmi physical interaction relationship: participates_in CCO:I0015661 ! nmi-q96ih6 physical interaction relationship: participates_in CCO:I0015715 ! nmi-snapc5 physical interaction relationship: participates_in CCO:I0015783 ! necap2-nmi physical interaction relationship: participates_in CCO:I0015818 ! nmi-tuba2 physical interaction relationship: participates_in CCO:I0017321 ! lsm4-nmi physical interaction relationship: participates_in CCO:I0017390 ! mycn-nmi-1 physical interaction relationship: participates_in CCO:I0017398 ! mycn-nmi-6 physical interaction relationship: participates_in CCO:I0018130 ! nmi-stat3-1 physical interaction relationship: participates_in CCO:I0018131 ! nmi-stat6-1 physical interaction relationship: participates_in CCO:I0018408 ! nmi-sox10-1 physical interaction relationship: participates_in CCO:I0018409 ! sox10-nmi-2 physical interaction relationship: participates_in CCO:I0019416 ! tuba2-nmi physical interaction relationship: participates_in CCO:I0019481 ! nmi-stat4-1 physical interaction relationship: participates_in CCO:I0019513 ! mycn-nmi-2 physical interaction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:B0005696 name: DNJB6_HUMAN def: "DnaJ homolog subfamily B member 6" [UniProtKB:O75190] synonym: "Heat shock protein J2" EXACT [UniProtKB:O75190] synonym: "HHDJ1" EXACT [UniProtKB:O75190] synonym: "HSJ-2" EXACT [UniProtKB:O75190] synonym: "MRJ" EXACT [UniProtKB:O75190] synonym: "MSJ-1" EXACT [UniProtKB:O75190] xref: EMBL:AAD16010.1 xref: EMBL:AAD43194.1 xref: EMBL:AAF21257.1 xref: EMBL:AAH00177.1 xref: EMBL:AAH02446.1 xref: EMBL:AAS07392.1 xref: EMBL:AAS07393.1 xref: EMBL:BAA32209.1 xref: EMBL:BAA88769.1 xref: EMBL:BAA88770.1 xref: EMBL:BAD93096.1 xref: EMBL:BAD97321.1 xref: EMBL:CAB66642.1 xref: EMBL:CAG38529.1 xref: EMBL:EAL23923.1 xref: EMBL:EAL23924.1 xref: UniProtKB:A4D232 xref: UniProtKB:O75190 xref: UniProtKB:O95806 xref: UniProtKB:Q53EN8 xref: UniProtKB:Q59EF2 xref: UniProtKB:Q6FIC8 xref: UniProtKB:Q75MA2 xref: UniProtKB:Q9UIK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004490 ! DNAJB6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006941 ! brms1-dnajb6 physical interaction relationship: participates_in CCO:I0007720 ! dnajb6-brms1 physical interaction relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011552 ! DNJB6_HUMAN-Phosphoserine277 [Term] id: CCO:B0005697 name: IMA5_HUMAN def: "Importin subunit alpha-6" [UniProtKB:O15131] synonym: "Karyopherin subunit alpha-5" EXACT [UniProtKB:O15131] xref: EMBL:AAC51868.1 xref: EMBL:AAH47409.1 xref: EMBL:CAI20500.1 xref: UniProtKB:O15131 xref: UniProtKB:Q86X23 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004888 ! KPNA5_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006942 ! brms1-kpna5 physical interaction relationship: participates_in CCO:I0007558 ! cdn1b-kpna5-1 physical interaction relationship: participates_in CCO:I0007559 ! cdn1b-kpna5-2 physical interaction relationship: participates_in CCO:I0007560 ! cdn1b-kpna5-3 physical interaction relationship: participates_in CCO:I0007741 ! cdn1b-kpna5-4 physical interaction relationship: participates_in CCO:I0007862 ! cdn1b-kpna5-5 physical interaction relationship: participates_in CCO:I0019149 ! anp32a-kpna5 physical interaction [Term] id: CCO:B0005698 name: HS90A_HUMAN def: "Heat shock protein HSP 90-alpha" [UniProtKB:P07900] synonym: "HSP 86" EXACT [UniProtKB:P07900] synonym: "Renal carcinoma antigen NY-REN-38" EXACT [UniProtKB:P07900] xref: EMBL:AAA36023.1 xref: EMBL:AAA63194.1 xref: EMBL:AAH00987.1 xref: EMBL:AAI21063.1 xref: EMBL:ABC40730.1 xref: EMBL:BAA13430.1 xref: EMBL:BAA13431.1 xref: EMBL:CAA30255.1 xref: EMBL:CAA33259.1 xref: EMBL:CAI64495.1 xref: EMBL:CAI64496.1 xref: UniProtKB:P07900 xref: UniProtKB:Q2PP14 xref: UniProtKB:Q5CAQ6 xref: UniProtKB:Q5CAQ7 xref: UniProtKB:Q9BVQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004830 ! HSP90AA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006539 ! cdh1-ctnna1-1 physical interaction relationship: participates_in CCO:I0006943 ! brms1-hspa8 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:I0007182 ! nuak2-cdc37-1 physical interaction relationship: participates_in CCO:I0007396 ! cdc37-hsp90 physical interaction relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0016347 ! map3k8-hspca physical interaction relationship: participates_in CCO:I0016418 ! nfkbib-hspca physical interaction relationship: participates_in CCO:I0016430 ! nfkbie-hspca physical interaction relationship: participates_in CCO:I0016825 ! nfkb2-hspca-1 physical interaction relationship: participates_in CCO:I0016904 ! ripk1-hspca physical interaction relationship: participates_in CCO:I0016917 ! ripk2-hspca physical interaction relationship: participates_in CCO:I0016932 ! map3k7ip1-hspca physical interaction relationship: participates_in CCO:I0016955 ! q9nyj8-hspca physical interaction relationship: participates_in CCO:I0017081 ! tradd-hspca physical interaction relationship: participates_in CCO:I0017108 ! traf1-hspca physical interaction relationship: participates_in CCO:I0017130 ! traf2-hspca physical interaction relationship: participates_in CCO:I0017201 ! map3k14-hspca physical interaction relationship: participates_in CCO:I0017206 ! chuk-hspca physical interaction relationship: participates_in CCO:I0017209 ! ikbkb-hspca physical interaction relationship: participates_in CCO:I0017213 ! ikbke-hspca physical interaction relationship: participates_in CCO:I0017217 ! ikbkg-hspca physical interaction relationship: participates_in CCO:I0017227 ! map3k1-hspca physical interaction relationship: participates_in CCO:I0017238 ! map3k3-hspca physical interaction relationship: participates_in CCO:I0017257 ! tbk1-hspca physical interaction relationship: participates_in CCO:I0017319 ! lsm1-hspca physical interaction relationship: participates_in CCO:I0017800 ! hsp90aa1-mmp2 physical interaction relationship: participates_in CCO:I0018298 ! ahsa1-hspca-1 physical interaction relationship: participates_in CCO:I0018845 ! hspca-rps3a-1 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:I0019362 ! dicer1-eif2c2-4 physical interaction relationship: participates_in CCO:I0019547 ! rps3a-hspca physical interaction relationship: participates_in CCO:I0020036 ! hspca-hspca physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: transforms_into CCO:B0012263 ! HS90A_HUMAN-Phosphothreonine5 relationship: transforms_into CCO:B0012264 ! HS90A_HUMAN-Phosphothreonine7 relationship: transforms_into CCO:B0012265 ! HS90A_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0012266 ! HS90A_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0012267 ! HS90A_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0031331 ! HS90A_HUMAN-Phosphotyrosine313 relationship: transforms_into CCO:B0031332 ! HS90A_HUMAN-Phosphotyrosine492 [Term] id: CCO:B0005699 name: HSP7C_HUMAN def: "Heat shock cognate 71 kDa protein" [UniProtKB:P11142] synonym: "Heat shock 70 kDa protein 8" EXACT [UniProtKB:P11142] xref: EMBL:AAH16179.1 xref: EMBL:AAH16660.1 xref: EMBL:AAH19816.1 xref: EMBL:AAK17898.1 xref: EMBL:BAB18615.1 xref: EMBL:CAA68445.1 xref: UniProtKB:P11142 xref: UniProtKB:Q9H3R6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004838 ! HSPA8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006943 ! brms1-hspa8 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008158 ! rgs2-hspa8 physical interaction relationship: participates_in CCO:I0008334 ! tada3l-hspa8 physical interaction relationship: participates_in CCO:I0016350 ! rel-hspa8 physical interaction relationship: participates_in CCO:I0016371 ! nfkbia-hspa8 physical interaction relationship: participates_in CCO:I0016390 ! nfkbib-hspa8 physical interaction relationship: participates_in CCO:I0016450 ! ikbkb-hspa8 physical interaction relationship: participates_in CCO:I0016466 ! ikbke-hspa8 physical interaction relationship: participates_in CCO:I0016529 ! ikbkg-hspa8 physical interaction relationship: participates_in CCO:I0016572 ! tank-hspa8 physical interaction relationship: participates_in CCO:I0016595 ! map3k1-hspa8 physical interaction relationship: participates_in CCO:I0016723 ! map3k3-hspa8 physical interaction relationship: participates_in CCO:I0016778 ! nfkb2-hspa8-1 physical interaction relationship: participates_in CCO:I0016855 ! relb-hspa8 physical interaction relationship: participates_in CCO:I0016894 ! ripk1-hspa8 physical interaction relationship: participates_in CCO:I0016907 ! ripk2-hspa8 physical interaction relationship: participates_in CCO:I0016924 ! map3k7ip1-hspa8 physical interaction relationship: participates_in CCO:I0016938 ! q9nyj8-hspa8 physical interaction relationship: participates_in CCO:I0016960 ! tbk1-hspa8 physical interaction relationship: participates_in CCO:I0016987 ! tnfrsf1a-hspa8 physical interaction relationship: participates_in CCO:I0017060 ! tradd-hspa8 physical interaction relationship: participates_in CCO:I0017089 ! traf1-hspa8 physical interaction relationship: participates_in CCO:I0017115 ! traf2-hspa8 physical interaction relationship: participates_in CCO:I0017136 ! traf6-hspa8 physical interaction relationship: participates_in CCO:I0018233 ! gch1-hsc70-1 physical interaction relationship: participates_in CCO:I0018623 ! gch1-hsc70 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: transforms_into CCO:B0012276 ! HSP7C_HUMAN-Phosphotyrosine15 relationship: transforms_into CCO:B0012277 ! HSP7C_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0012278 ! HSP7C_HUMAN-Phosphothreonine477 relationship: transforms_into CCO:B0031334 ! HSP7C_HUMAN-Phosphotyrosine41 relationship: transforms_into CCO:B0066933 ! HSP7C_HUMAN-Phosphotyrosine107 [Term] id: CCO:B0005700 name: H4_HUMAN def: "Histone H4" [UniProtKB:P62805] xref: EMBL:AAA52652.1 xref: EMBL:AAA63188.1 xref: EMBL:AAH10926.1 xref: EMBL:AAH12587.1 xref: EMBL:AAH16336.1 xref: EMBL:AAH17361.1 xref: EMBL:AAH20884.1 xref: EMBL:AAH50615.1 xref: EMBL:AAH54014.1 xref: EMBL:AAH66248.1 xref: EMBL:AAH66249.1 xref: EMBL:AAH66250.1 xref: EMBL:AAH67495.1 xref: EMBL:AAH67496.1 xref: EMBL:AAH67497.1 xref: EMBL:AAH69288.1 xref: EMBL:AAH69392.1 xref: EMBL:AAH69467.1 xref: EMBL:AAH69654.1 xref: EMBL:AAH75806.1 xref: EMBL:AAH93763.1 xref: EMBL:AAH93765.1 xref: EMBL:AAH93969.1 xref: EMBL:AAI08261.1 xref: EMBL:AAI11094.1 xref: EMBL:AAI11435.1 xref: EMBL:AAI12194.1 xref: EMBL:AAI20940.1 xref: EMBL:AAI28105.1 xref: EMBL:AAI28106.1 xref: EMBL:AAI30559.1 xref: EMBL:AAI30561.1 xref: EMBL:AAI43046.1 xref: EMBL:AAM83108.1 xref: EMBL:AAN01438.1 xref: EMBL:AAN01439.1 xref: EMBL:AAN01440.1 xref: EMBL:AAN01441.1 xref: EMBL:AAN01442.1 xref: EMBL:AAN01443.1 xref: EMBL:AAN01444.1 xref: EMBL:AAN01446.1 xref: EMBL:AAN01447.1 xref: EMBL:AAN01448.1 xref: EMBL:AAN01449.1 xref: EMBL:AAN01450.1 xref: EMBL:AAT68253.1 xref: EMBL:BAA19208.1 xref: EMBL:CAA16946.1 xref: EMBL:CAA24918.1 xref: EMBL:CAA43011.1 xref: EMBL:CAA43012.1 xref: EMBL:CAA43013.1 xref: EMBL:CAA43014.1 xref: EMBL:CAA43016.1 xref: EMBL:CAA43017.1 xref: EMBL:CAA47464.1 xref: EMBL:CAA58538.1 xref: EMBL:CAB02549.1 xref: EMBL:CAC03414.1 xref: EMBL:CAC03418.1 xref: EMBL:CAC03426.1 xref: EMBL:CAC03427.1 xref: EMBL:CAC04128.1 xref: EMBL:CAC69642.1 xref: EMBL:CAD24074.1 xref: EMBL:CAG46966.1 xref: EMBL:CAG46969.1 xref: EMBL:CAG46977.1 xref: EMBL:CAG46984.1 xref: EMBL:CAG46986.1 xref: EMBL:CAI12560.1 xref: EMBL:CAI12567.1 xref: EMBL:EAW55509.1 xref: EMBL:EAW55510.1 xref: EMBL:EAW55538.1 xref: EMBL:EAW55549.1 xref: EMBL:EAW55555.1 xref: EMBL:EAW96325.1 xref: EMBL:EAX03086.1 xref: EMBL:EAX03111.1 xref: EMBL:EAX03112.1 xref: EMBL:EAX03121.1 xref: UniProtKB:A2VCL0 xref: UniProtKB:P02304 xref: UniProtKB:P02305 xref: UniProtKB:P62805 xref: UniProtKB:Q6DRA9 xref: UniProtKB:Q6FGB8 xref: UniProtKB:Q6NWP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004763 ! HIST1H4A_human relationship: encoded_by CCO:G0004764 ! HIST1H4B_human relationship: encoded_by CCO:G0004765 ! HIST1H4C_human relationship: encoded_by CCO:G0004766 ! HIST1H4D_human relationship: encoded_by CCO:G0004767 ! HIST1H4E_human relationship: encoded_by CCO:G0004768 ! HIST1H4F_human relationship: encoded_by CCO:G0004769 ! HIST1H4H_human relationship: encoded_by CCO:G0004770 ! HIST1H4I_human relationship: encoded_by CCO:G0004771 ! HIST1H4J_human relationship: encoded_by CCO:G0004772 ! HIST1H4K_human relationship: encoded_by CCO:G0004773 ! HIST1H4L_human relationship: encoded_by CCO:G0004774 ! HIST2H4A_human relationship: encoded_by CCO:G0004775 ! HIST4H4_human relationship: encoded_by CCO:G0013376 ! HIST2H4B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006004 ! daxx-dek-1 physical interaction relationship: participates_in CCO:I0006949 ! dek-daxx-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016641 ! map3k1-h4f2 physical interaction relationship: participates_in CCO:I0016747 ! map3k3-h4f2 physical interaction relationship: participates_in CCO:I0017027 ! tnfrsf1a-h4f2 physical interaction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0012133 ! H4_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0012134 ! H4_HUMAN-dimethylarginine4 relationship: transforms_into CCO:B0012135 ! H4_HUMAN-N6-acetyllysine6 relationship: transforms_into CCO:B0012136 ! H4_HUMAN-N6-acetyllysine9 relationship: transforms_into CCO:B0012137 ! H4_HUMAN-N6-acetyllysine13 relationship: transforms_into CCO:B0012138 ! H4_HUMAN-N6-acetyllysine17 relationship: transforms_into CCO:B0012139 ! H4_HUMAN-N6,N6-dimethyllysine21 relationship: transforms_into CCO:B0012140 ! H4_HUMAN-N6-methyllysine21 relationship: transforms_into CCO:B0012141 ! H4_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0031329 ! H4_HUMAN-Phosphotyrosine52 relationship: transforms_into CCO:B0031330 ! H4_HUMAN-Phosphotyrosine89 relationship: transforms_into CCO:B0041139 ! H4_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0041140 ! H4_HUMAN-Citrulline4 relationship: transforms_into CCO:B0041141 ! H4_HUMAN-Omega-N-methylarginine4 relationship: transforms_into CCO:B0041142 ! H4_HUMAN-N6,N6,N6-trimethyllysine21 [Term] id: CCO:B0005701 name: HDA11_HUMAN def: "Histone deacetylase 11" [UniProtKB:Q96DB2] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q96DB2] synonym: "HD11" EXACT [UniProtKB:Q96DB2] xref: EMBL:AAH09676.1 xref: EMBL:BAB15127.1 xref: EMBL:BAB15272.1 xref: EMBL:CAB70712.1 xref: UniProtKB:Q96DB2 xref: UniProtKB:Q9H6I7 xref: UniProtKB:Q9H6X3 xref: UniProtKB:Q9NTC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004785 ! HDAC11_human relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0006950 ! hdac6-hdac11-1 physical interaction relationship: participates_in CCO:I0008372 ! cdkn1a-hdac11 physical interaction relationship: participates_in CCO:I0020194 ! th1l-hdac11 physical interaction relationship: participates_in CCO:I0020401 ! phyhip-hdac11 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005702 name: STK4_HUMAN def: "Serine/threonine-protein kinase 4" [UniProtKB:Q13043] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13043] synonym: "Mammalian STE20-like protein kinase 1" EXACT [UniProtKB:Q13043] synonym: "MST-1" EXACT [UniProtKB:Q13043] synonym: "Serine/threonine-protein kinase Krs-2" EXACT [UniProtKB:Q13043] synonym: "STE20-like kinase MST1" EXACT [UniProtKB:Q13043] xref: EMBL:AAA83254.1 xref: EMBL:AAB17262.1 xref: EMBL:AAH29511.1 xref: EMBL:AAH58916.1 xref: EMBL:AAH93768.1 xref: EMBL:CAB07508.2 xref: EMBL:CAI19815.1 xref: EMBL:CAI95633.1 xref: EMBL:CAI95634.1 xref: UniProtKB:Q13043 xref: UniProtKB:Q15802 xref: UniProtKB:Q4G156 xref: UniProtKB:Q5H982 xref: UniProtKB:Q6PD60 xref: UniProtKB:Q9BR32 xref: UniProtKB:Q9NTZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005694 ! STK4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006951 ! stk4-rassf5-1 physical interaction relationship: participates_in CCO:I0015856 ! stk4-sav1-1 physical interaction relationship: participates_in CCO:I0015999 ! stk4-sav1-2 physical interaction relationship: participates_in CCO:I0016001 ! stk4-sav1-3 physical interaction relationship: participates_in CCO:I0019482 ! stk4-stk4-1 physical interaction relationship: participates_in CCO:I0019483 ! stk4-stk4-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0014254 ! STK4_HUMAN-Phosphothreonine183 relationship: transforms_into CCO:B0014255 ! STK4_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0014256 ! STK4_HUMAN-Phosphotyrosine433 relationship: transforms_into CCO:B0048401 ! STK4_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005703 name: ABI1_HUMAN def: "Abl interactor 1" [UniProtKB:Q8IZP0] synonym: "Abelson interactor 1" EXACT [UniProtKB:Q8IZP0] synonym: "Abi-1" EXACT [UniProtKB:Q8IZP0] synonym: "Abl-binding protein 4" EXACT [UniProtKB:Q8IZP0] synonym: "AblBP4" EXACT [UniProtKB:Q8IZP0] synonym: "e3B1" EXACT [UniProtKB:Q8IZP0] synonym: "Eps8 SH3 domain-binding protein" EXACT [UniProtKB:Q8IZP0] synonym: "Eps8-binding protein" EXACT [UniProtKB:Q8IZP0] synonym: "Nap1-binding protein" EXACT [UniProtKB:Q8IZP0] synonym: "Nap1BP" EXACT [UniProtKB:Q8IZP0] synonym: "Spectrin SH3 domain-binding protein 1" EXACT [UniProtKB:Q8IZP0] xref: EMBL:AAB62569.1 xref: EMBL:AAC39757.1 xref: EMBL:AAD00897.1 xref: EMBL:AAF70309.1 xref: EMBL:AAH24254.1 xref: EMBL:AAN28379.1 xref: EMBL:BAB55675.1 xref: EMBL:CAB88006.1 xref: EMBL:CAH73117.1 xref: EMBL:CAH73119.1 xref: EMBL:CAI17273.1 xref: EMBL:CAI17279.1 xref: UniProtKB:O15147 xref: UniProtKB:O76049 xref: UniProtKB:O95060 xref: UniProtKB:Q5W070 xref: UniProtKB:Q5W072 xref: UniProtKB:Q8IZP0 xref: UniProtKB:Q8TB63 xref: UniProtKB:Q96S81 xref: UniProtKB:Q9NXZ9 xref: UniProtKB:Q9NYB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004012 ! ABI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006953 ! abi1-nckap1-1 physical interaction relationship: participates_in CCO:I0007069 ! abi1-abl1-2 physical interaction relationship: participates_in CCO:I0007527 ! abi1-abl1-1 physical interaction relationship: participates_in CCO:I0015897 ! abi1-ncf1-1 physical interaction relationship: participates_in CCO:I0015918 ! abi1-ncf1-3 physical interaction relationship: participates_in CCO:I0015919 ! abi1-ncf1-4 physical interaction relationship: participates_in CCO:I0016226 ! abi1-ncf1-2 physical interaction relationship: participates_in CCO:I0018139 ! abi1-spta1-2 physical interaction relationship: participates_in CCO:I0018143 ! abi1-nckap1-3 physical interaction relationship: participates_in CCO:I0018769 ! abi1-nck1 physical interaction relationship: participates_in CCO:I0019226 ! abi1-spta1-1 physical interaction relationship: participates_in CCO:I0019227 ! abi1-ncf3-3 physical interaction relationship: participates_in CCO:I0019343 ! abi1-nckap1-2 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0010395 ! ABI1_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0010397 ! ABI1_HUMAN-Phosphotyrosine333 relationship: transforms_into CCO:B0031286 ! ABI1_HUMAN-Phosphotyrosine455 relationship: transforms_into CCO:B0041283 ! ABI1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0048152 ! ABI1_HUMAN-Phosphotyrosine213 relationship: transforms_into CCO:B0065276 ! ABI1_HUMAN-Phosphoserine216 [Term] id: CCO:B0005704 name: ZYX_HUMAN def: "Zyxin" [UniProtKB:Q15942] synonym: "Zyxin-2" EXACT [UniProtKB:Q15942] xref: EMBL:AAH08743.1 xref: EMBL:AAH09360.1 xref: EMBL:AAH10031.1 xref: EMBL:AAS07459.1 xref: EMBL:CAA64447.1 xref: EMBL:CAA65050.1 xref: EMBL:CAG33712.1 xref: UniProtKB:Q15942 xref: UniProtKB:Q6I9S4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005976 ! ZYX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006954 ! lats1-zyx-1 physical interaction relationship: participates_in CCO:I0007236 ! lats1-zyx-6 colocalization relationship: participates_in CCO:I0007728 ! lats1-zyx-4 physical interaction relationship: participates_in CCO:I0007950 ! lats1-zyx-2 physical interaction relationship: participates_in CCO:I0007951 ! lats1-zyx-3 physical interaction relationship: participates_in CCO:I0007952 ! lats1-zyx-5 physical interaction relationship: participates_in CCO:I0007953 ! lats1-zyx-7 physical interaction relationship: participates_in CCO:I0007958 ! lats1-zyx-8 physical interaction relationship: participates_in CCO:I0007959 ! lats1-zyx-9 physical interaction relationship: participates_in CCO:I0007960 ! lats1-zyx-10 physical interaction relationship: participates_in CCO:I0019071 ! atxn1-zyx physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0014769 ! ZYX_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0014770 ! ZYX_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0014771 ! ZYX_HUMAN-Phosphothreonine159 relationship: transforms_into CCO:B0014772 ! ZYX_HUMAN-Phosphothreonine179 relationship: transforms_into CCO:B0014773 ! ZYX_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0014774 ! ZYX_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0014775 ! ZYX_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0014776 ! ZYX_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0014777 ! ZYX_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0014778 ! ZYX_HUMAN-Phosphoserine344 relationship: transforms_into CCO:B0041223 ! ZYX_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0048430 ! ZYX_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0072282 ! ZYX_HUMAN-Phosphoserine169 relationship: transforms_into CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 relationship: transforms_into CCO:B0072284 ! ZYX_HUMAN-Phosphothreonine274 relationship: transforms_into CCO:B0072285 ! ZYX_HUMAN-Phosphoserine288 [Term] id: CCO:B0005705 name: MYOD1_HUMAN def: "Myoblast determination protein 1" [UniProtKB:P15172] synonym: "Myf-3" EXACT [UniProtKB:P15172] synonym: "Myogenic factor 3" EXACT [UniProtKB:P15172] xref: EMBL:AAC29001.1 xref: EMBL:AAH64493.1 xref: EMBL:AAP35821.1 xref: EMBL:CAA35640.1 xref: EMBL:CAA40000.1 xref: EMBL:EAW68427.1 xref: UniProtKB:O75321 xref: UniProtKB:P15172 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005147 ! MYOD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006958 ! sirt2-pcaf-myod1-2 physical interaction relationship: participates_in CCO:I0007536 ! sirt2-pcaf-myod1-1 physical interaction [Term] id: CCO:B0005706 name: M4K2_HUMAN def: "Mitogen-activated protein kinase kinase kinase kinase 2" [UniProtKB:Q12851] synonym: "B lymphocyte serine/threonine-protein kinase" EXACT [UniProtKB:Q12851] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q12851] synonym: "GC kinase" EXACT [UniProtKB:Q12851] synonym: "Germinal center kinase" EXACT [UniProtKB:Q12851] synonym: "MAPK/ERK kinase kinase kinase 2" EXACT [UniProtKB:Q12851] synonym: "MEK kinase kinase 2" EXACT [UniProtKB:Q12851] synonym: "MEKKK 2" EXACT [UniProtKB:Q12851] synonym: "Rab8-interacting protein" EXACT [UniProtKB:Q12851] xref: EMBL:AAA20968.1 xref: UniProtKB:Q12851 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005011 ! MAP4K2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: participates_in CCO:I0006963 ! map4k2-mlk3-1 physical interaction relationship: participates_in CCO:I0015921 ! map4k2-mekk1-2 physical interaction relationship: participates_in CCO:I0015950 ! map4k2-mekk1-1 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0067831 ! M4K2_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0067832 ! M4K2_HUMAN-Phosphoserine394 [Term] id: CCO:B0005707 name: TNR14_HUMAN def: "Tumor necrosis factor receptor superfamily member 14 precursor" [UniProtKB:Q92956] synonym: "Herpesvirus entry mediator A" EXACT [UniProtKB:Q92956] synonym: "TR2" EXACT [UniProtKB:Q92956] synonym: "Tumor necrosis factor receptor-like 2" EXACT [UniProtKB:Q92956] xref: EMBL:AAB58354.1 xref: EMBL:AAD00505.1 xref: EMBL:AAF75588.1 xref: EMBL:AAH02794.1 xref: EMBL:AAL47717.1 xref: EMBL:AAL47718.1 xref: EMBL:AAQ89238.1 xref: EMBL:AAR23264.1 xref: EMBL:CAG33190.1 xref: UniProtKB:Q6IB95 xref: UniProtKB:Q8WXR1 xref: UniProtKB:Q92956 xref: UniProtKB:Q96J31 xref: UniProtKB:Q9UM65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005802 ! TNFRSF14_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001358 ! tumor necrosis factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006964 ! hvem-lt_alpha physical interaction relationship: participates_in CCO:I0015923 ! atar-traf5-3 physical interaction relationship: participates_in CCO:I0015924 ! atar-traf5-4 physical interaction relationship: participates_in CCO:I0015925 ! atar-traf2-9 physical interaction relationship: participates_in CCO:I0016115 ! hvem-light physical interaction relationship: participates_in CCO:I0016263 ! light-hvem physical interaction relationship: participates_in CCO:I0017367 ! atar-traf5 physical interaction relationship: participates_in CCO:I0018033 ! atar-traf5-5 physical interaction relationship: participates_in CCO:I0018180 ! hvem-traf1 physical interaction relationship: participates_in CCO:I0018181 ! hvem-traf3 physical interaction relationship: participates_in CCO:I0018182 ! hvem-traf5 physical interaction relationship: participates_in CCO:I0020201 ! tnfrsf14-chd3 physical interaction relationship: participates_in CCO:I0020202 ! tnfrsf14-vim physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0005708 name: ARAF_HUMAN def: "A-Raf proto-oncogene serine/threonine-protein kinase" [UniProtKB:P10398] synonym: "A-raf-1" EXACT [UniProtKB:P10398] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P10398] synonym: "Proto-oncogene Pks" EXACT [UniProtKB:P10398] xref: EMBL:AAA65219.1 xref: EMBL:AAB03517.1 xref: EMBL:AAB08754.1 xref: EMBL:AAH02466.1 xref: EMBL:AAV38667.1 xref: EMBL:CAA28476.1 xref: EMBL:CAI42468.1 xref: UniProtKB:P07557 xref: UniProtKB:P10398 xref: UniProtKB:Q5H9B3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004087 ! ARAF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006965 ! araf-pbk physical interaction relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0007553 ! araf-hras physical interaction relationship: participates_in CCO:I0007554 ! araf-pbk-1 physical interaction relationship: participates_in CCO:I0007555 ! araf-pbk-2 physical interaction relationship: participates_in CCO:I0016207 ! map2k2-araf-1 physical interaction relationship: participates_in CCO:I0018047 ! araf-th1l-1 physical interaction relationship: participates_in CCO:I0018048 ! araf-c20orf14-1 physical interaction relationship: participates_in CCO:I0018049 ! araf-htim44 physical interaction relationship: participates_in CCO:I0018050 ! araf-cps1 physical interaction relationship: participates_in CCO:I0018051 ! araf-rras2 physical interaction relationship: participates_in CCO:I0018052 ! araf-ass physical interaction relationship: participates_in CCO:I0018053 ! araf-cops3 physical interaction relationship: participates_in CCO:I0018054 ! araf-nudt14 physical interaction relationship: participates_in CCO:I0018799 ! araf-rabggtb physical interaction relationship: participates_in CCO:I0018800 ! araf-th1l physical interaction relationship: participates_in CCO:I0018801 ! araf-c20orf14 physical interaction relationship: participates_in CCO:I0018802 ! araf-efemp1 physical interaction relationship: participates_in CCO:I0018803 ! araf-rabggtb-1 physical interaction relationship: participates_in CCO:I0018804 ! araf-c20orf14-2 physical interaction relationship: participates_in CCO:I0018805 ! araf-htim44-1 physical interaction relationship: participates_in CCO:I0018806 ! araf-ass-1 physical interaction relationship: participates_in CCO:I0018807 ! araf-th1l-2 physical interaction relationship: participates_in CCO:I0018808 ! araf-efemp1-1 physical interaction relationship: participates_in CCO:I0018809 ! araf-pkm2 physical interaction relationship: participates_in CCO:I0018810 ! araf-nudt14-1 physical interaction relationship: participates_in CCO:I0018811 ! araf-cops3-1 physical interaction relationship: participates_in CCO:I0018812 ! araf-rras2-1 physical interaction relationship: participates_in CCO:I0018813 ! araf-cps1-1 physical interaction relationship: participates_in CCO:I0018814 ! araf-rabggtb-2 physical interaction relationship: participates_in CCO:I0018815 ! araf-th1l-3 physical interaction relationship: participates_in CCO:I0018816 ! araf-c20orf14-3 physical interaction relationship: participates_in CCO:I0018817 ! araf-htim44-2 physical interaction relationship: participates_in CCO:I0018818 ! araf-ass-2 physical interaction relationship: participates_in CCO:I0018819 ! araf-nudt14-2 physical interaction relationship: participates_in CCO:I0018820 ! araf-cops3-2 physical interaction relationship: participates_in CCO:I0018821 ! araf-rras2-2 physical interaction relationship: participates_in CCO:I0018822 ! araf-efemp1-2 physical interaction relationship: participates_in CCO:I0018823 ! araf-cps1-2 physical interaction relationship: participates_in CCO:I0018824 ! araf-ass-3 physical interaction relationship: participates_in CCO:I0019188 ! map2k2-araf-2 physical interaction relationship: participates_in CCO:I0019189 ! map2k2-araf-3 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0010585 ! ARAF_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0010586 ! ARAF_HUMAN-Phosphoserine582 relationship: transforms_into CCO:B0048171 ! ARAF_HUMAN-Phosphothreonine213 relationship: transforms_into CCO:B0048172 ! ARAF_HUMAN-Phosphothreonine215 [Term] id: CCO:B0005709 name: HUWE1_HUMAN def: "E3 ubiquitin-protein ligase HUWE1" [UniProtKB:Q7Z6Z7] synonym: "ARF-binding protein 1" EXACT [UniProtKB:Q7Z6Z7] synonym: "ARF-BP1" EXACT [UniProtKB:Q7Z6Z7] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q7Z6Z7] synonym: "HECT, UBA and WWE domain-containing protein 1" EXACT [UniProtKB:Q7Z6Z7] synonym: "HectH9" EXACT [UniProtKB:Q7Z6Z7] synonym: "Homologous to E6AP carboxyl terminus homologous protein 9" EXACT [UniProtKB:Q7Z6Z7] synonym: "Large structure of UREB1" EXACT [UniProtKB:Q7Z6Z7] synonym: "LASU1" EXACT [UniProtKB:Q7Z6Z7] synonym: "Mcl-1 ubiquitin ligase E3" EXACT [UniProtKB:Q7Z6Z7] synonym: "Mule" EXACT [UniProtKB:Q7Z6Z7] synonym: "Upstream regulatory element-binding protein 1" EXACT [UniProtKB:Q7Z6Z7] synonym: "URE-B1" EXACT [UniProtKB:Q7Z6Z7] synonym: "URE-binding protein 1" EXACT [UniProtKB:Q7Z6Z7] xref: EMBL:AAC62492.1 xref: EMBL:AAF28950.1 xref: EMBL:AAH02602.2 xref: EMBL:AAH63505.1 xref: EMBL:AAV90838.1 xref: EMBL:AAX24125.1 xref: EMBL:AAY98258.1 xref: EMBL:BAA20771.2 xref: EMBL:BAB13404.1 xref: EMBL:BAC06833.1 xref: EMBL:CAB82393.1 xref: EMBL:CAG33094.1 xref: EMBL:CAI39580.1 xref: EMBL:CAI42354.1 xref: EMBL:CAI42654.1 xref: UniProtKB:O15029 xref: UniProtKB:Q4G2Z2 xref: UniProtKB:Q5H961 xref: UniProtKB:Q6P4D0 xref: UniProtKB:Q7Z6Z7 xref: UniProtKB:Q8NG67 xref: UniProtKB:Q9BUI0 xref: UniProtKB:Q9HCJ4 xref: UniProtKB:Q9NSL6 xref: UniProtKB:Q9P0A9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004844 ! HUWE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006970 ! huew1-tp53-1 physical interaction relationship: participates_in CCO:I0006971 ! tp53-huew1-2 physical interaction relationship: participates_in CCO:I0007256 ! huew1-cdkn2a-1 physical interaction relationship: participates_in CCO:I0007257 ! cdkn2a-huew1-3 physical interaction relationship: participates_in CCO:I0007426 ! cdkn2a-huew1-2 physical interaction relationship: participates_in CCO:I0007568 ! tp53-huew1-1 physical interaction relationship: participates_in CCO:I0007874 ! cdkn2a-huew1-1 physical interaction relationship: transforms_into CCO:B0012287 ! HUWE1_HUMAN-Phosphoserine1395 relationship: transforms_into CCO:B0012288 ! HUWE1_HUMAN-Phosphoserine1907 relationship: transforms_into CCO:B0012289 ! HUWE1_HUMAN-Phosphoserine2362 relationship: transforms_into CCO:B0012290 ! HUWE1_HUMAN-Phosphoserine2377 relationship: transforms_into CCO:B0012291 ! HUWE1_HUMAN-Phosphoserine2887 relationship: transforms_into CCO:B0012292 ! HUWE1_HUMAN-Phosphoserine2918 relationship: transforms_into CCO:B0012293 ! HUWE1_HUMAN-Phosphoserine3757 relationship: transforms_into CCO:B0012294 ! HUWE1_HUMAN-Phosphoserine3797 relationship: transforms_into CCO:B0012295 ! HUWE1_HUMAN-Phosphoserine3808 relationship: transforms_into CCO:B0012296 ! HUWE1_HUMAN-Phosphoserine3816 relationship: transforms_into CCO:B0012297 ! HUWE1_HUMAN-Phosphothreonine3822 relationship: transforms_into CCO:B0012298 ! HUWE1_HUMAN-Phosphoserine3919 relationship: transforms_into CCO:B0012299 ! HUWE1_HUMAN-Phosphothreonine3924 relationship: transforms_into CCO:B0012300 ! HUWE1_HUMAN-Phosphothreonine3927 relationship: transforms_into CCO:B0012301 ! HUWE1_HUMAN-Phosphotyrosine4271 relationship: transforms_into CCO:B0048282 ! HUWE1_HUMAN-Phosphoserine1084 relationship: transforms_into CCO:B0048283 ! HUWE1_HUMAN-Phosphoserine2526 relationship: transforms_into CCO:B0066959 ! HUWE1_HUMAN-Phosphoserine1368 relationship: transforms_into CCO:B0066960 ! HUWE1_HUMAN-Phosphoserine2365 relationship: transforms_into CCO:B0066961 ! HUWE1_HUMAN-Phosphoserine3662 [Term] id: CCO:B0005710 name: ZHANG_HUMAN def: "CREB/ATF bZIP transcription factor" [UniProtKB:Q9NS37] synonym: "HCF-binding transcription factor Zhangfei" EXACT [UniProtKB:Q9NS37] synonym: "Host cell factor-binding transcription factor Zhangfei" EXACT [UniProtKB:Q9NS37] xref: EMBL:AAD28325.1 xref: EMBL:AAH93796.1 xref: EMBL:AAH93798.1 xref: EMBL:AAZ42189.1 xref: UniProtKB:Q52LT3 xref: UniProtKB:Q9NS37 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005955 ! CREBZF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006973 ! hcfc1-zf-1 physical interaction relationship: participates_in CCO:I0006974 ! hcfc1-zf-3 physical interaction relationship: participates_in CCO:I0007264 ! hcfc1-creb3-3 direct interaction relationship: participates_in CCO:I0007265 ! hcfc1-zf-6 direct interaction relationship: participates_in CCO:I0007267 ! hcfc1-zf-7 direct interaction relationship: participates_in CCO:I0007754 ! hcfc1-zf-4 physical interaction relationship: participates_in CCO:I0007755 ! hcfc1-zf-5 physical interaction relationship: participates_in CCO:I0007875 ! hcfc1-zf-2 physical interaction [Term] id: CCO:B0005711 name: P3C2B_HUMAN def: "Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide" [UniProtKB:O00750] synonym: "C2-PI3K" EXACT [UniProtKB:O00750] synonym: "EC 2.7.1.154" EXACT [UniProtKB:O00750] synonym: "Phosphoinositide 3-Kinase-C2-beta" EXACT [UniProtKB:O00750] synonym: "PI3K-C2beta" EXACT [UniProtKB:O00750] synonym: "PtdIns-3-kinase C2 beta" EXACT [UniProtKB:O00750] xref: EMBL:CAA72168.1 xref: EMBL:CAA74194.1 xref: EMBL:CAI16572.1 xref: UniProtKB:O00750 xref: UniProtKB:O95666 xref: UniProtKB:Q5SW99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005244 ! PIK3C2B_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0005554 ! phosphatidylinositol-4-phosphate 3-kinase activity relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006978 ! egfr-pik3c2b-2 physical interaction relationship: participates_in CCO:I0006979 ! egfr-pik3c2b-5 physical interaction relationship: participates_in CCO:I0007428 ! egfr-pik3c2b-3 direct interaction relationship: participates_in CCO:I0007429 ! egfr-pik3c2b-6 direct interaction relationship: participates_in CCO:I0007570 ! egfr-pik3c2b-4 physical interaction relationship: participates_in CCO:I0007877 ! egfr-pik3c2a-1 physical interaction relationship: participates_in CCO:I0007878 ! egfr-pik3c2b-1 physical interaction relationship: participates_in CCO:I0015951 ! erbb2-pik3c2b-2 direct interaction relationship: participates_in CCO:I0019389 ! erbb2-pik3c2a-1 physical interaction relationship: participates_in CCO:I0019390 ! pdgfr-pik3c2b-1 physical interaction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0005712 name: ADA17_HUMAN def: "ADAM 17 precursor" [UniProtKB:P78536] synonym: "A disintegrin and metalloproteinase domain 17" EXACT [UniProtKB:P78536] synonym: "CD156b antigen" EXACT [UniProtKB:P78536] synonym: "EC 3.4.24.86" EXACT [UniProtKB:P78536] synonym: "Snake venom-like protease" EXACT [UniProtKB:P78536] synonym: "TNF-alpha convertase" EXACT [UniProtKB:P78536] synonym: "TNF-alpha-converting enzyme" EXACT [UniProtKB:P78536] xref: EMBL:AAB51514.1 xref: EMBL:AAB51586.1 xref: EMBL:AAB53014.1 xref: EMBL:AAC39721.1 xref: UniProtKB:O60226 xref: UniProtKB:P78536 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004027 ! ADAM17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006988 ! adam17-mad2l1-1 physical interaction relationship: participates_in CCO:I0006989 ! adam17-mad2l1-3 physical interaction relationship: participates_in CCO:I0007360 ! adam17-mad2l1-2 physical interaction relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: transforms_into CCO:B0010453 ! ADA17_HUMAN-Phosphotyrosine379 relationship: transforms_into CCO:B0010454 ! ADA17_HUMAN-Phosphoserine382 relationship: transforms_into CCO:B0010455 ! ADA17_HUMAN-Phosphothreonine735 relationship: transforms_into CCO:B0010456 ! ADA17_HUMAN-Phosphoserine791 relationship: transforms_into CCO:B0010457 ! ADA17_HUMAN-Phosphoserine819 [Term] id: CCO:B0005713 name: ANM1_HUMAN def: "Protein arginine N-methyltransferase 1" [UniProtKB:Q99873] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q99873] synonym: "Interferon receptor 1-bound protein 4" EXACT [UniProtKB:Q99873] xref: EMBL:AAF62893.1 xref: EMBL:AAF62894.1 xref: EMBL:AAF62895.1 xref: EMBL:BAA11029.1 xref: EMBL:CAA71763.1 xref: EMBL:CAA71764.1 xref: EMBL:CAA71765.1 xref: UniProtKB:Q15529 xref: UniProtKB:Q99872 xref: UniProtKB:Q99873 xref: UniProtKB:Q99874 xref: UniProtKB:Q9NZ04 xref: UniProtKB:Q9NZ05 xref: UniProtKB:Q9NZ06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004063 ! PRMT1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001757 ! N-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006991 ! hrmt1l2-ilf3-2 methylation relationship: participates_in CCO:I0007785 ! hrmt1l2-ilf3-3 physical interaction relationship: participates_in CCO:I0008014 ! hrmt1l2-rif1 physical interaction relationship: participates_in CCO:I0008767 ! hrmt1l2-hmga2 physical interaction relationship: participates_in CCO:I0018172 ! dhx9-hrmt1l2-1 physical interaction relationship: participates_in CCO:I0018173 ! hrmt1l2-dhx9-1 physical interaction relationship: participates_in CCO:I0019736 ! hnrpr-hrmt1l2 physical interaction relationship: participates_in CCO:I0019737 ! hrmt1l2-med31 physical interaction relationship: participates_in CCO:I0019738 ! hrmt1l2-hrmt1l2 physical interaction relationship: participates_in CCO:I0019877 ! wdr33-hrmt1l2 physical interaction relationship: participates_in CCO:I0019930 ! ylpm1-hrmt1l2 physical interaction relationship: participates_in CCO:I0020006 ! fus-hrmt1l2 physical interaction relationship: participates_in CCO:I0020030 ! hrmt1l2-igsf21 physical interaction relationship: participates_in CCO:I0020237 ! arpc3-hrmt1l2 physical interaction relationship: participates_in CCO:I0020447 ! s100a8-hrmt1l2 physical interaction relationship: participates_in CCO:I0020575 ! hrmt1l2-idh3b physical interaction relationship: participates_in CCO:I0020608 ! nol4-hrmt1l2 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0065639 ! ANM1_HUMAN-Phosphotyrosine299 [Term] id: CCO:B0005714 name: BNI3L_HUMAN def: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like" [UniProtKB:O60238] synonym: "Adenovirus E1B19K-binding protein B5" EXACT [UniProtKB:O60238] synonym: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A" EXACT [UniProtKB:O60238] synonym: "NIP3-like protein X" EXACT [UniProtKB:O60238] synonym: "NIP3L" EXACT [UniProtKB:O60238] xref: EMBL:AAC27723.1 xref: EMBL:AAD03589.1 xref: EMBL:AAF70290.1 xref: EMBL:AAH01559.1 xref: EMBL:AAH09603.1 xref: EMBL:AAL50978.1 xref: EMBL:AAN04051.1 xref: EMBL:AAV38308.1 xref: EMBL:BAA28692.1 xref: UniProtKB:O60238 xref: UniProtKB:Q8NF87 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004176 ! BNIP3L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006993 ! bnip3alpha-bcl_2-1 direct interaction relationship: participates_in CCO:I0006994 ! bnip3alpha-bcl_2-2 direct interaction relationship: participates_in CCO:I0008498 ! rint1-bnip3l physical interaction relationship: participates_in CCO:I0015116 ! bnip3l-ewsr1 physical interaction relationship: participates_in CCO:I0015568 ! bnip3-bnip3l physical interaction relationship: participates_in CCO:I0015663 ! bnip3l-tmem11 physical interaction relationship: participates_in CCO:I0018081 ! bnip3alpha-bcl_xl-1 direct interaction relationship: participates_in CCO:I0018082 ! bnip3alpha-bcl_xl-2 direct interaction relationship: transforms_into CCO:B0010816 ! BNI3L_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0010817 ! BNI3L_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0010818 ! BNI3L_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0010819 ! BNI3L_HUMAN-Phosphoserine120 [Term] id: CCO:B0005715 name: ITF2_HUMAN def: "Transcription factor 4" [UniProtKB:P15884] synonym: "Immunoglobulin transcription factor 2" EXACT [UniProtKB:P15884] synonym: "ITF-2" EXACT [UniProtKB:P15884] synonym: "SEF-2" EXACT [UniProtKB:P15884] synonym: "SL3-3 enhancer factor 2" EXACT [UniProtKB:P15884] xref: EMBL:AAA60310.1 xref: EMBL:AAA60311.1 xref: EMBL:AAA60312.1 xref: EMBL:AAC51824.1 xref: EMBL:AAI25085.1 xref: EMBL:AAI25086.1 xref: EMBL:CAA36298.1 xref: UniProtKB:P15884 xref: UniProtKB:Q08AP2 xref: UniProtKB:Q08AP3 xref: UniProtKB:Q15439 xref: UniProtKB:Q15440 xref: UniProtKB:Q15441 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004905 ! TCF4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0007000 ! cdc73-tcf4 physical interaction relationship: participates_in CCO:I0017372 ! tcf4-bcl9 physical interaction relationship: participates_in CCO:I0017708 ! hash1-e2_2-2 direct interaction relationship: participates_in CCO:I0018092 ! hash1-e2_2-1 physical interaction relationship: participates_in CCO:I0018226 ! hash1-e2_2-3 physical interaction relationship: participates_in CCO:I0018227 ! e2_2-hash1-1 physical interaction relationship: participates_in CCO:I0018230 ! e2_2-e2_2-1 physical interaction relationship: participates_in CCO:I0018548 ! hash1-e2_2-4 physical interaction relationship: participates_in CCO:I0018550 ! hash1-e2_2-5 physical interaction relationship: participates_in CCO:I0019297 ! ebox-hash1-e2_2-1 direct interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0048288 ! ITF2_HUMAN-Phosphoserine372 [Term] id: CCO:B0005716 name: PSN1_HUMAN def: "Presenilin-1" [UniProtKB:P49768] synonym: "EC 3.4.23.-" EXACT [UniProtKB:P49768] synonym: "Protein S182" EXACT [UniProtKB:P49768] synonym: "PS-1" EXACT [UniProtKB:P49768] xref: EMBL:AAB05894.1 xref: EMBL:AAB05895.1 xref: EMBL:AAB46370.1 xref: EMBL:AAB46371.1 xref: EMBL:AAB46416.1 xref: EMBL:AAC97960.1 xref: EMBL:AAF19253.1 xref: EMBL:AAF19254.1 xref: EMBL:AAH11729.1 xref: EMBL:AAL16811.1 xref: EMBL:BAA20883.1 xref: EMBL:CAA07825.1 xref: UniProtKB:O95465 xref: UniProtKB:P49768 xref: UniProtKB:Q14762 xref: UniProtKB:Q15719 xref: UniProtKB:Q15720 xref: UniProtKB:Q96P33 xref: UniProtKB:Q9UIF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005394 ! PSEN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007011 ! tcf7l2-ctnnb1 physical interaction relationship: participates_in CCO:I0007701 ! ctnnb1-tcf7l2-4 physical interaction relationship: participates_in CCO:I0007705 ! tcf7l2-ctnnb1-3 physical interaction relationship: participates_in CCO:I0007706 ! jup-psen1-7 physical interaction relationship: participates_in CCO:I0007804 ! tcf7l2-ctnnb1-5 physical interaction relationship: participates_in CCO:I0007805 ! tcf7l2-ctnnb1-6 physical interaction relationship: participates_in CCO:I0016196 ! tmed10-psen1-4 physical interaction relationship: participates_in CCO:I0017773 ! tmed10-psen1-3 physical interaction relationship: participates_in CCO:I0018095 ! ctnnb1-psen1 physical interaction relationship: participates_in CCO:I0018096 ! jup-psen1-1 physical interaction relationship: participates_in CCO:I0018565 ! tmed10-psen1-5 physical interaction relationship: participates_in CCO:I0018697 ! tmed10-psen1 physical interaction relationship: participates_in CCO:I0018884 ! tmed10-psen1-1 physical interaction relationship: participates_in CCO:I0019309 ! ctnnb1-psen1-1 physical interaction relationship: participates_in CCO:I0019310 ! jup-psen1 physical interaction relationship: participates_in CCO:I0019311 ! jup-psen1-2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000755 ! Notch receptor processing relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: transforms_into CCO:B0013636 ! PSN1_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0013637 ! PSN1_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: transforms_into CCO:B0013639 ! PSN1_HUMAN-Phosphoserine367 [Term] id: CCO:B0005717 name: EDC3_HUMAN def: "Enhancer of mRNA-decapping protein 3" [UniProtKB:Q96F86] synonym: "hYjeF_N2" EXACT [UniProtKB:Q96F86] synonym: "LSM16 homolog" EXACT [UniProtKB:Q96F86] synonym: "YjeF domain-containing protein 1" EXACT [UniProtKB:Q96F86] synonym: "YjeF N-terminal domain-containing protein 2" EXACT [UniProtKB:Q96F86] synonym: "YjeF_N2" EXACT [UniProtKB:Q96F86] xref: EMBL:AAG22486.1 xref: EMBL:AAH11534.1 xref: EMBL:AAH21271.1 xref: EMBL:BAB15001.1 xref: UniProtKB:Q96F86 xref: UniProtKB:Q9H797 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004542 ! EDC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007016 ! upf1-rcd8 physical interaction relationship: participates_in CCO:I0018110 ! zfp36-yjdc physical interaction relationship: participates_in CCO:I0018111 ! zfp36-rcd8-1 physical interaction relationship: transforms_into CCO:B0011624 ! EDC3_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0048247 ! EDC3_HUMAN-Phosphoserine161 [Term] id: CCO:B0005719 name: VGFR1_HUMAN def: "Vascular endothelial growth factor receptor 1 precursor" [UniProtKB:P17948] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P17948] synonym: "Flt-1" EXACT [UniProtKB:P17948] synonym: "Fms-like tyrosine kinase 1" EXACT [UniProtKB:P17948] synonym: "Tyrosine-protein kinase FRT" EXACT [UniProtKB:P17948] synonym: "Tyrosine-protein kinase receptor FLT" EXACT [UniProtKB:P17948] synonym: "Vascular permeability factor receptor" EXACT [UniProtKB:P17948] synonym: "VEGFR-1" EXACT [UniProtKB:P17948] xref: EMBL:AAC16449.2 xref: EMBL:AAC50060.1 xref: EMBL:AAH39007.1 xref: EMBL:BAA00080.1 xref: EMBL:CAA35946.1 xref: UniProtKB:O60722 xref: UniProtKB:P16057 xref: UniProtKB:P17948 xref: UniProtKB:Q12954 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005901 ! FLT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007020 ! flt1-vegf-1 direct interaction relationship: participates_in CCO:I0007468 ! flt1-vegf-2 direct interaction relationship: participates_in CCO:I0007470 ! flt1-pgf-1 direct interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway relationship: transforms_into CCO:B0014613 ! VGFR1_HUMAN-Phosphotyrosine1053 relationship: transforms_into CCO:B0014614 ! VGFR1_HUMAN-Phosphotyrosine1169 relationship: transforms_into CCO:B0014615 ! VGFR1_HUMAN-Phosphotyrosine1213 relationship: transforms_into CCO:B0014616 ! VGFR1_HUMAN-Phosphotyrosine1242 relationship: transforms_into CCO:B0014617 ! VGFR1_HUMAN-Phosphotyrosine1327 relationship: transforms_into CCO:B0014618 ! VGFR1_HUMAN-Phosphotyrosine1333 relationship: transforms_into CCO:B0071792 ! VGFR1_HUMAN-Phosphotyrosine1048 [Term] id: CCO:B0005720 name: MSH3_HUMAN def: "DNA mismatch repair protein Msh3" [UniProtKB:P20585] synonym: "Divergent upstream protein" EXACT [UniProtKB:P20585] synonym: "DUP" EXACT [UniProtKB:P20585] synonym: "Mismatch repair protein 1" EXACT [UniProtKB:P20585] synonym: "MRP1" EXACT [UniProtKB:P20585] xref: EMBL:AAB06045.1 xref: EMBL:AAB47281.1 xref: EMBL:AAH11817.1 xref: EMBL:AAP13535.1 xref: EMBL:BAD27111.1 xref: UniProtKB:P20585 xref: UniProtKB:Q6PJT5 xref: UniProtKB:Q86UQ6 xref: UniProtKB:Q92867 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005127 ! MSH3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007028 ! msh2-msh3 physical interaction relationship: participates_in CCO:I0007029 ! msh3-msh2-1 physical interaction relationship: participates_in CCO:I0007033 ! msh3-msh2-2 physical interaction relationship: participates_in CCO:I0007035 ! msh3-msh2-3 physical interaction relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0013015 ! MSH3_HUMAN-Phosphoserine201 relationship: transforms_into CCO:B0048331 ! MSH3_HUMAN-Phosphotyrosine1068 [Term] id: CCO:B0005721 name: WAPL_HUMAN def: "Wings apart-like protein homolog" [UniProtKB:Q7Z5K2] synonym: "Friend of EBNA2 protein" EXACT [UniProtKB:Q7Z5K2] xref: EMBL:AAO14651.1 xref: EMBL:BAA13391.1 xref: EMBL:BAC78631.1 xref: EMBL:CAH73376.1 xref: EMBL:CAI16708.1 xref: UniProtKB:Q5VSK5 xref: UniProtKB:Q7Z5K2 xref: UniProtKB:Q8IX10 xref: UniProtKB:Q92549 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005910 ! WAPAL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007036 ! wapl-cspg6 physical interaction relationship: participates_in CCO:I0007037 ! wapl-cspg6-3 physical interaction relationship: participates_in CCO:I0007039 ! wapl-cspg6-1 physical interaction relationship: participates_in CCO:I0007040 ! wapl-cspg6-2 physical interaction relationship: participates_in CCO:I0007711 ! wapl-cspg6-4 physical interaction relationship: participates_in CCO:I0007712 ! wapl-cspg6-5 physical interaction relationship: participates_in CCO:I0007713 ! wapl-cspg6-6 physical interaction relationship: participates_in CCO:I0007714 ! wapl-cspg6-7 physical interaction relationship: participates_in CCO:I0007715 ! wapl-cspg6-9 physical interaction relationship: transforms_into CCO:B0014649 ! WAPL_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0014650 ! WAPL_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0014651 ! WAPL_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0014652 ! WAPL_HUMAN-Phosphoserine459 relationship: transforms_into CCO:B0014653 ! WAPL_HUMAN-Phosphoserine461 relationship: transforms_into CCO:B0036040 ! WAPL_HUMAN-Phosphoserine223 relationship: transforms_into CCO:B0071821 ! WAPL_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0071822 ! WAPL_HUMAN-Phosphoserine904 [Term] id: CCO:B0005722 name: FBRL_HUMAN def: "rRNA 2'-O-methyltransferase fibrillarin" [UniProtKB:P22087] synonym: "34 kDa nucleolar scleroderma antigen" EXACT [UniProtKB:P22087] synonym: "EC 2.1.1.-" EXACT [UniProtKB:P22087] xref: EMBL:AAA52453.1 xref: EMBL:AAC28913.1 xref: EMBL:AAD15623.1 xref: EMBL:AAH19260.1 xref: EMBL:AAP35476.1 xref: EMBL:AAV38946.1 xref: EMBL:CAA39935.1 xref: EMBL:CAG33350.1 xref: UniProtKB:O75259 xref: UniProtKB:P22087 xref: UniProtKB:Q6IAT5 xref: UniProtKB:Q9UPI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004618 ! FBL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018637 ! baz2a-fbl colocalization relationship: participates_in CCO:I0020308 ! fbl-tbc1d17 physical interaction relationship: transforms_into CCO:B0011851 ! FBRL_HUMAN-Asymmetric dimethylarginine8 relationship: transforms_into CCO:B0011852 ! FBRL_HUMAN-Asymmetric dimethylarginine15 relationship: transforms_into CCO:B0011853 ! FBRL_HUMAN-Asymmetric dimethylarginine21 relationship: transforms_into CCO:B0011854 ! FBRL_HUMAN-Asymmetric dimethylarginine24 relationship: transforms_into CCO:B0011855 ! FBRL_HUMAN-Asymmetric dimethylarginine27 relationship: transforms_into CCO:B0011856 ! FBRL_HUMAN-Asymmetric dimethylarginine34 relationship: transforms_into CCO:B0011857 ! FBRL_HUMAN-Asymmetric dimethylarginine36 relationship: transforms_into CCO:B0011858 ! FBRL_HUMAN-Asymmetric dimethylarginine41 relationship: transforms_into CCO:B0011859 ! FBRL_HUMAN-Asymmetric dimethylarginine43 relationship: transforms_into CCO:B0011860 ! FBRL_HUMAN-Asymmetric dimethylarginine45 relationship: transforms_into CCO:B0011861 ! FBRL_HUMAN-Asymmetric dimethylarginine59 relationship: transforms_into CCO:B0011862 ! FBRL_HUMAN-Asymmetric dimethylarginine70 relationship: transforms_into CCO:B0011863 ! FBRL_HUMAN-Asymmetric dimethylarginine72 relationship: transforms_into CCO:B0011864 ! FBRL_HUMAN-Asymmetric dimethylarginine74 relationship: transforms_into CCO:B0011865 ! FBRL_HUMAN-Asymmetric dimethylarginine78 [Term] id: CCO:B0005723 name: MTR1A_HUMAN def: "Melatonin receptor type 1A" [UniProtKB:P48039] synonym: "Mel-1A-R" EXACT [UniProtKB:P48039] synonym: "Mel1a melatonin receptor" EXACT [UniProtKB:P48039] xref: EMBL:AAB17720.1 xref: EMBL:AAH74946.1 xref: EMBL:AAH74947.1 xref: EMBL:AAI26298.1 xref: EMBL:AAI26300.1 xref: EMBL:BAA85303.1 xref: UniProtKB:A0AVC5 xref: UniProtKB:P48039 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005134 ! MTNR1A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001956 ! melatonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0005724 name: MTR1B_HUMAN def: "Melatonin receptor type 1B" [UniProtKB:P49286] synonym: "Mel-1B-R" EXACT [UniProtKB:P49286] synonym: "Mel1b melatonin receptor" EXACT [UniProtKB:P49286] xref: EMBL:AAC50612.1 xref: EMBL:AAH69163.1 xref: EMBL:AAS00461.1 xref: EMBL:BAA92315.1 xref: UniProtKB:P49286 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005135 ! MTNR1B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001956 ! melatonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0005725 name: ROA2_HUMAN def: "Heterogeneous nuclear ribonucleoproteins A2/B1" [UniProtKB:P22626] synonym: "hnRNP A2 / hnRNP B1" EXACT [UniProtKB:P22626] xref: EMBL:AAA36574.1 xref: EMBL:AAA60271.1 xref: EMBL:AAB60650.1 xref: EMBL:BAA06031.1 xref: EMBL:BAA06032.1 xref: EMBL:BAF82118.1 xref: UniProtKB:A8K064 xref: UniProtKB:P22626 xref: UniProtKB:P22627 xref: UniProtKB:Q9UC98 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006369 ! HNRNPA2B1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0013923 ! ROA2_HUMAN-Phosphothreonine176 relationship: transforms_into CCO:B0013924 ! ROA2_HUMAN-Omega-N-methylarginine203 relationship: transforms_into CCO:B0013925 ! ROA2_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0013926 ! ROA2_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0013927 ! ROA2_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0013928 ! ROA2_HUMAN-Phosphoserine344 relationship: transforms_into CCO:B0013929 ! ROA2_HUMAN-Phosphotyrosine347 [Term] id: CCO:B0005726 name: RS24_HUMAN def: "40S ribosomal protein S24" [UniProtKB:P62847] xref: EMBL:AAA36588.1 xref: EMBL:AAB08006.1 xref: EMBL:AAB08007.1 xref: EMBL:AAH00523.1 xref: EMBL:AAH71926.1 xref: UniProtKB:P16632 xref: UniProtKB:P62847 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005535 ! RPS24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0016832 ! nfkb2-rps24 physical interaction relationship: transforms_into CCO:B0013940 ! RS24_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0031372 ! RS24_HUMAN-Phosphotyrosine81 [Term] id: CCO:B0005727 name: TBB5_HUMAN def: "Tubulin beta chain" [UniProtKB:P07437] synonym: "Tubulin beta-5 chain" EXACT [UniProtKB:P07437] xref: EMBL:AAB59507.1 xref: EMBL:AAC28642.1 xref: EMBL:AAC28650.1 xref: EMBL:AAC28654.1 xref: EMBL:AAD33873.1 xref: EMBL:AAH01938.1 xref: EMBL:AAH02347.1 xref: EMBL:AAH05838.1 xref: EMBL:AAH07605.1 xref: EMBL:AAH13374.1 xref: EMBL:AAH19924.1 xref: EMBL:AAH20946.1 xref: EMBL:AAH21909.1 xref: EMBL:AAH70326.1 xref: EMBL:BAB63321.1 xref: EMBL:BAB93480.1 xref: EMBL:BAC54932.1 xref: UniProtKB:P05218 xref: UniProtKB:P07437 xref: UniProtKB:Q8WUC1 xref: UniProtKB:Q9CY33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005737 ! TUBB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005975 ! zo_1-actn4 physical interaction relationship: participates_in CCO:I0007067 ! tubg-mark4-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0017473 ! disc1-tubb2 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:P0002050 ! natural killer cell mediated cytotoxicity relationship: transforms_into CCO:B0014317 ! TBB5_HUMAN-Phosphotyrosine36 relationship: transforms_into CCO:B0031380 ! TBB5_HUMAN-Phosphotyrosine340 [Term] id: CCO:B0005728 name: IF4A2_HUMAN def: "Eukaryotic initiation factor 4A-II" [UniProtKB:Q14240] synonym: "ATP-dependent RNA helicase eIF4A-2" EXACT [UniProtKB:Q14240] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q14240] synonym: "eIF-4A-II" EXACT [UniProtKB:Q14240] synonym: "eIF4A-II" EXACT [UniProtKB:Q14240] xref: EMBL:AAH12547.1 xref: EMBL:AAH13708.1 xref: EMBL:AAH15842.1 xref: EMBL:AAH48105.1 xref: EMBL:BAA06336.1 xref: UniProtKB:Q14240 xref: UniProtKB:Q96B90 xref: UniProtKB:Q96EA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004863 ! EIF4A2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007328 ! eif4gii-eif4aii physical interaction relationship: participates_in CCO:I0016286 ! eif4g1-eif4a2-3 physical interaction relationship: participates_in CCO:I0018571 ! eif4g1-eif4a2-1 physical interaction relationship: participates_in CCO:I0018673 ! eif4g1-eif4a2-2 physical interaction relationship: participates_in CCO:I0019966 ! ddx24-eif4a2 physical interaction relationship: participates_in CCO:I0020547 ! eif4a2-clns1a physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation [Term] id: CCO:B0005729 name: DDX5_HUMAN def: "Probable ATP-dependent RNA helicase DDX5" [UniProtKB:P17844] synonym: "DEAD box protein 5" EXACT [UniProtKB:P17844] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P17844] synonym: "RNA helicase p68" EXACT [UniProtKB:P17844] xref: EMBL:AAB84094.1 xref: EMBL:AAH16027.1 xref: EMBL:AAP35589.1 xref: EMBL:CAA09408.1 xref: EMBL:CAA33751.1 xref: EMBL:CAA36324.1 xref: UniProtKB:O75681 xref: UniProtKB:P17844 xref: UniProtKB:Q53Y61 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004459 ! DDX5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017096 ! traf1-ddx5 physical interaction relationship: transforms_into CCO:B0011481 ! DDX5_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0011482 ! DDX5_HUMAN-Phosphotyrosine297 relationship: transforms_into CCO:B0011483 ! DDX5_HUMAN-Omega-N-methylated arginine502 relationship: transforms_into CCO:B0011484 ! DDX5_HUMAN-Phosphothreonine507 relationship: transforms_into CCO:B0011485 ! DDX5_HUMAN-Phosphoserine520 relationship: transforms_into CCO:B0064719 ! DDX5_HUMAN-Phosphotyrosine202 [Term] id: CCO:B0005730 name: CH60_HUMAN def: "60 kDa heat shock protein, mitochondrial precursor" [UniProtKB:P10809] synonym: "60 kDa chaperonin" EXACT [UniProtKB:P10809] synonym: "Chaperonin 60" EXACT [UniProtKB:P10809] synonym: "CPN60" EXACT [UniProtKB:P10809] synonym: "Heat shock protein 60" EXACT [UniProtKB:P10809] synonym: "HSP-60" EXACT [UniProtKB:P10809] synonym: "Hsp60" EXACT [UniProtKB:P10809] synonym: "HuCHA60" EXACT [UniProtKB:P10809] synonym: "Mitochondrial matrix protein P1" EXACT [UniProtKB:P10809] synonym: "P60 lymphocyte protein" EXACT [UniProtKB:P10809] xref: EMBL:AAA36022.1 xref: EMBL:AAA60127.1 xref: EMBL:AAH02676.1 xref: EMBL:AAH03030.1 xref: EMBL:AAH67082.1 xref: EMBL:AAH73746.1 xref: EMBL:ABB01006.1 xref: EMBL:CAB75426.1 xref: UniProtKB:P10809 xref: UniProtKB:Q38L19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004343 ! HSPD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016565 ! ikbkg-hspd1 physical interaction relationship: participates_in CCO:I0017632 ! hsp-60-npm_alk physical interaction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0011197 ! CH60_HUMAN-Phosphoserine70 relationship: transforms_into CCO:B0011198 ! CH60_HUMAN-Phosphotyrosine223 relationship: transforms_into CCO:B0011199 ! CH60_HUMAN-Phosphotyrosine227 [Term] id: CCO:B0005731 name: ANXA6_HUMAN def: "Annexin A6" [UniProtKB:P08133] synonym: "67 kDa calelectrin" EXACT [UniProtKB:P08133] synonym: "Annexin VI" EXACT [UniProtKB:P08133] synonym: "Annexin-6" EXACT [UniProtKB:P08133] synonym: "Calphobindin-II" EXACT [UniProtKB:P08133] synonym: "Chromobindin-20" EXACT [UniProtKB:P08133] synonym: "CPB-II" EXACT [UniProtKB:P08133] synonym: "Lipocortin VI" EXACT [UniProtKB:P08133] synonym: "p68" EXACT [UniProtKB:P08133] synonym: "p70" EXACT [UniProtKB:P08133] synonym: "Protein III" EXACT [UniProtKB:P08133] xref: EMBL:AAA35656.1 xref: EMBL:AAH17046.1 xref: EMBL:BAA00400.1 xref: EMBL:BAC86715.1 xref: EMBL:CAA68286.1 xref: UniProtKB:P08133 xref: UniProtKB:Q6ZT79 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004071 ! ANXA6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0010562 ! ANXA6_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0031291 ! ANXA6_HUMAN-Phosphotyrosine30 relationship: transforms_into CCO:B0031292 ! ANXA6_HUMAN-Phosphotyrosine201 [Term] id: CCO:B0005732 name: HNRH1_HUMAN def: "Heterogeneous nuclear ribonucleoprotein H" [UniProtKB:P31943] synonym: "hnRNP H" EXACT [UniProtKB:P31943] xref: EMBL:AAA91346.1 xref: EMBL:AAH01348.1 xref: EMBL:CAG33059.1 xref: UniProtKB:P31943 xref: UniProtKB:Q6IBM4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014350 ! HNRNPH1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016354 ! rel-hnrph1 physical interaction relationship: participates_in CCO:I0016470 ! ikbke-hnrph1 physical interaction relationship: participates_in CCO:I0016691 ! map3k3-hnrph1 physical interaction relationship: participates_in CCO:I0016943 ! q9nyj8-hnrph1 physical interaction relationship: transforms_into CCO:B0012200 ! HNRH1_HUMAN-N-acetylmethionine2 relationship: transforms_into CCO:B0012201 ! HNRH1_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0012202 ! HNRH1_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0012203 ! HNRH1_HUMAN-Phosphothreonine100 relationship: transforms_into CCO:B0012204 ! HNRH1_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0012205 ! HNRH1_HUMAN-Asymmetric dimethylarginine217 relationship: transforms_into CCO:B0012206 ! HNRH1_HUMAN-Phosphotyrosine246 relationship: transforms_into CCO:B0012207 ! HNRH1_HUMAN-Phosphotyrosine306 relationship: transforms_into CCO:B0012208 ! HNRH1_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0048276 ! HNRH1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0066854 ! HNRH1_HUMAN-Phosphothreonine107 [Term] id: CCO:B0005733 name: NUCL_HUMAN def: "Nucleolin" [UniProtKB:P19338] synonym: "Protein C23" EXACT [UniProtKB:P19338] xref: EMBL:AAA59954.1 xref: EMBL:AAY24247.1 xref: EMBL:BAC03738.1 xref: UniProtKB:P19338 xref: UniProtKB:Q53SK1 xref: UniProtKB:Q8NB06 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005220 ! NCL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007294 ! pa2g4-ncl-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016419 ! nfkbib-ncl physical interaction relationship: participates_in CCO:I0016644 ! map3k1-ncl physical interaction relationship: participates_in CCO:I0016826 ! nfkb2-ncl physical interaction relationship: participates_in CCO:I0017272 ! nucleolin-myh9-1 physical interaction relationship: participates_in CCO:I0017825 ! nucleolin-myh9-2 physical interaction relationship: participates_in CCO:I0017965 ! nucleolin-myh9-3 colocalization relationship: transforms_into CCO:B0013269 ! NUCL_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0013270 ! NUCL_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0013271 ! NUCL_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0013272 ! NUCL_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0013273 ! NUCL_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0013274 ! NUCL_HUMAN-Phosphothreonine69 relationship: transforms_into CCO:B0013275 ! NUCL_HUMAN-Phosphothreonine76 relationship: transforms_into CCO:B0013276 ! NUCL_HUMAN-Phosphothreonine121 relationship: transforms_into CCO:B0013277 ! NUCL_HUMAN-Phosphoserine145 relationship: transforms_into CCO:B0013278 ! NUCL_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0013279 ! NUCL_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0013280 ! NUCL_HUMAN-Phosphothreonine214 relationship: transforms_into CCO:B0013281 ! NUCL_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0013282 ! NUCL_HUMAN-Phosphoserine580 relationship: transforms_into CCO:B0013283 ! NUCL_HUMAN-Phosphoserine619 relationship: transforms_into CCO:B0026383 ! NUCL_HUMAN-Phosphothreonine99 relationship: transforms_into CCO:B0026384 ! NUCL_HUMAN-Phosphothreonine105 relationship: transforms_into CCO:B0031361 ! NUCL_HUMAN-Phosphoserine206 [Term] id: CCO:B0005734 name: RS8_HUMAN def: "40S ribosomal protein S8" [UniProtKB:P62241] xref: EMBL:AAH70875.1 xref: EMBL:BAB93488.1 xref: EMBL:CAA47670.1 xref: UniProtKB:P09058 xref: UniProtKB:P62241 xref: UniProtKB:Q6IRL7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005539 ! RPS8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016642 ! map3k1-rps8 physical interaction relationship: participates_in CCO:I0016821 ! nfkb2-rps8 physical interaction relationship: participates_in CCO:I0016975 ! tbk1-rps8 physical interaction relationship: transforms_into CCO:B0013944 ! RS8_HUMAN-Phosphoserine160 relationship: transforms_into CCO:B0070222 ! RS8_HUMAN-Phosphothreonine130 [Term] id: CCO:B0005736 name: ANXA2_HUMAN def: "Annexin A2" [UniProtKB:P07355] synonym: "Annexin II" EXACT [UniProtKB:P07355] synonym: "Annexin-2" EXACT [UniProtKB:P07355] synonym: "Calpactin I heavy chain" EXACT [UniProtKB:P07355] synonym: "Chromobindin-8" EXACT [UniProtKB:P07355] synonym: "Lipocortin II" EXACT [UniProtKB:P07355] synonym: "p36" EXACT [UniProtKB:P07355] synonym: "PAP-IV" EXACT [UniProtKB:P07355] synonym: "Placental anticoagulant protein IV" EXACT [UniProtKB:P07355] synonym: "Protein I" EXACT [UniProtKB:P07355] xref: EMBL:AAH01388.1 xref: EMBL:AAH09564.1 xref: EMBL:AAH15834.1 xref: EMBL:AAH16774.1 xref: EMBL:AAH21114.1 xref: EMBL:AAH52558.1 xref: EMBL:AAH52567.1 xref: EMBL:AAH66955.2 xref: EMBL:AAH68065.1 xref: EMBL:AAH93056.1 xref: EMBL:AAP36100.1 xref: EMBL:BAA00013.1 xref: UniProtKB:P07355 xref: UniProtKB:Q567R4 xref: UniProtKB:Q96DD5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004069 ! ANXA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0010556 ! ANXA2_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0010557 ! ANXA2_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0010558 ! ANXA2_HUMAN-Phosphothreonine19 relationship: transforms_into CCO:B0010559 ! ANXA2_HUMAN-Phosphotyrosine24 relationship: transforms_into CCO:B0010560 ! ANXA2_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0010561 ! ANXA2_HUMAN-Phosphotyrosine30 relationship: transforms_into CCO:B0048161 ! ANXA2_HUMAN-Phosphotyrosine188 relationship: transforms_into CCO:B0065650 ! ANXA2_HUMAN-Phosphotyrosine199 relationship: transforms_into CCO:B0065651 ! ANXA2_HUMAN-Phosphotyrosine238 relationship: transforms_into CCO:B0065652 ! ANXA2_HUMAN-Phosphotyrosine316 relationship: transforms_into CCO:B0065653 ! ANXA2_HUMAN-Phosphotyrosine317 relationship: transforms_into CCO:B0065654 ! ANXA2_HUMAN-Phosphotyrosine318 [Term] id: CCO:B0005737 name: VIME_HUMAN def: "Vimentin" [UniProtKB:P08670] xref: EMBL:AAA61279.1 xref: EMBL:AAA61281.2 xref: EMBL:AAA61282.1 xref: EMBL:AAH00163.2 xref: EMBL:AAH30573.1 xref: EMBL:AAH66956.1 xref: EMBL:AAN09720.1 xref: EMBL:BAB71275.1 xref: EMBL:BAC05002.1 xref: EMBL:BAD96227.1 xref: EMBL:BAD96322.1 xref: EMBL:BAF83332.1 xref: EMBL:CAA34499.1 xref: EMBL:CAA39600.1 xref: EMBL:CAA79613.2 xref: EMBL:CAB87963.1 xref: EMBL:CAG28618.1 xref: EMBL:EAW86215.1 xref: UniProtKB:P08670 xref: UniProtKB:Q15867 xref: UniProtKB:Q15868 xref: UniProtKB:Q15869 xref: UniProtKB:Q548L2 xref: UniProtKB:Q6LER9 xref: UniProtKB:Q8N850 xref: UniProtKB:Q96ML2 xref: UniProtKB:Q9NTM3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005903 ! VIM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0008118 ! hmg20b-vim physical interaction relationship: participates_in CCO:I0008127 ! kif15-vim physical interaction relationship: participates_in CCO:I0008155 ! rad51-vim physical interaction relationship: participates_in CCO:I0008186 ! vim-rif1 physical interaction relationship: participates_in CCO:I0008686 ! psma1-vim physical interaction relationship: participates_in CCO:I0008800 ! psme1-vim physical interaction relationship: participates_in CCO:I0014980 ! myst2-vim physical interaction relationship: participates_in CCO:I0015018 ! nif3l1-vim physical interaction relationship: participates_in CCO:I0015190 ! drr1-vim physical interaction relationship: participates_in CCO:I0015494 ! pdlim1-vim physical interaction relationship: participates_in CCO:I0016096 ! vim-sh3gl3 physical interaction relationship: participates_in CCO:I0016102 ! vim-setdb1 physical interaction relationship: participates_in CCO:I0016103 ! vim-hbo1 physical interaction relationship: participates_in CCO:I0016104 ! vim-zhx1 physical interaction relationship: participates_in CCO:I0016105 ! vim-pias4 physical interaction relationship: participates_in CCO:I0016552 ! ikbkg-vim physical interaction relationship: participates_in CCO:I0016640 ! map3k1-vim physical interaction relationship: participates_in CCO:I0016746 ! map3k3-vim physical interaction relationship: participates_in CCO:I0016916 ! ripk2-vim physical interaction relationship: participates_in CCO:I0017079 ! tradd-vim physical interaction relationship: participates_in CCO:I0019591 ! fubp1-vim physical interaction relationship: participates_in CCO:I0019669 ! bhlhb2-vim physical interaction relationship: participates_in CCO:I0019681 ! casp8-vim physical interaction relationship: participates_in CCO:I0019697 ! creb1-vim physical interaction relationship: participates_in CCO:I0019835 ! sirt6-vim physical interaction relationship: participates_in CCO:I0019875 ! vim-myst2 physical interaction relationship: participates_in CCO:I0019993 ! fabp4-vim physical interaction relationship: participates_in CCO:I0020029 ! triobp-vim physical interaction relationship: participates_in CCO:I0020059 ! mafg-vim physical interaction relationship: participates_in CCO:I0020088 ! nfatc2-vim physical interaction relationship: participates_in CCO:I0020177 ! stx1a-vim physical interaction relationship: participates_in CCO:I0020202 ! tnfrsf14-vim physical interaction relationship: participates_in CCO:I0020209 ! trim28-vim physical interaction relationship: transforms_into CCO:B0014619 ! VIME_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0014620 ! VIME_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0014621 ! VIME_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0014622 ! VIME_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0014623 ! VIME_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0014624 ! VIME_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0014625 ! VIME_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0014626 ! VIME_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0014627 ! VIME_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0014628 ! VIME_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0014629 ! VIME_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0014630 ! VIME_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0014631 ! VIME_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0014632 ! VIME_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0014633 ! VIME_HUMAN-Phosphoserine55 relationship: transforms_into CCO:B0014634 ! VIME_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0014635 ! VIME_HUMAN-Phosphotyrosine61 relationship: transforms_into CCO:B0014636 ! VIME_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0014637 ! VIME_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0014638 ! VIME_HUMAN-Phosphoserine73 relationship: transforms_into CCO:B0014639 ! VIME_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0014640 ! VIME_HUMAN-Phosphotyrosine117 relationship: transforms_into CCO:B0014641 ! VIME_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0014642 ! VIME_HUMAN-Phosphoserine412 relationship: transforms_into CCO:B0014643 ! VIME_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0014644 ! VIME_HUMAN-Phosphoserine430 relationship: transforms_into CCO:B0014645 ! VIME_HUMAN-Phosphothreonine446 relationship: transforms_into CCO:B0014646 ! VIME_HUMAN-Phosphothreonine458 relationship: transforms_into CCO:B0014647 ! VIME_HUMAN-Phosphoserine459 relationship: transforms_into CCO:B0031384 ! VIME_HUMAN-Phosphotyrosine53 relationship: transforms_into CCO:B0071800 ! VIME_HUMAN-Phosphotyrosine38 [Term] id: CCO:B0005738 name: VDAC3_HUMAN def: "Voltage-dependent anion-selective channel protein 3" [UniProtKB:Q9Y277] synonym: "hVDAC3" EXACT [UniProtKB:Q9Y277] synonym: "Outer mitochondrial membrane protein porin 3" EXACT [UniProtKB:Q9Y277] synonym: "VDAC-3" EXACT [UniProtKB:Q9Y277] xref: EMBL:AAB93872.1 xref: EMBL:AAC39876.1 xref: EMBL:AAD49610.1 xref: EMBL:AAH56870.1 xref: UniProtKB:Q9UIS0 xref: UniProtKB:Q9Y277 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005896 ! VDAC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: transforms_into CCO:B0014605 ! VDAC3_HUMAN-N6-acetyllysine20 relationship: transforms_into CCO:B0014606 ! VDAC3_HUMAN-Phosphothreonine33 relationship: transforms_into CCO:B0014607 ! VDAC3_HUMAN-N6-acetyllysine61 relationship: transforms_into CCO:B0014608 ! VDAC3_HUMAN-Phosphotyrosine195 relationship: transforms_into CCO:B0014609 ! VDAC3_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0031383 ! VDAC3_HUMAN-Phosphotyrosine48 [Term] id: CCO:B0005739 name: GBLP_HUMAN def: "Guanine nucleotide-binding protein subunit beta-2-like 1" [UniProtKB:P63244] synonym: "Guanine nucleotide-binding protein subunit beta-like protein 12.3" EXACT [UniProtKB:P63244] synonym: "RACK1" EXACT [UniProtKB:P63244] synonym: "Receptor for activated C kinase" EXACT [UniProtKB:P63244] synonym: "Receptor of activated protein kinase C 1" EXACT [UniProtKB:P63244] xref: EMBL:AAA59626.1 xref: EMBL:AAH00214.1 xref: EMBL:AAH00366.1 xref: EMBL:AAH10119.1 xref: EMBL:AAH14256.1 xref: EMBL:AAH14788.1 xref: EMBL:AAH17287.1 xref: EMBL:AAH19093.1 xref: EMBL:AAH19362.1 xref: EMBL:AAH21993.1 xref: EMBL:AAH32006.1 xref: EMBL:CAG33259.1 xref: UniProtKB:P25388 xref: UniProtKB:P63244 xref: UniProtKB:P99049 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004688 ! GNB2L1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001709 ! cell soma relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0008013 ! gnb2l1-ptn physical interaction relationship: participates_in CCO:I0008371 ! cdkn1a-gnb2l1 physical interaction relationship: participates_in CCO:I0015787 ! gnb2l1-tsc22d4 physical interaction relationship: participates_in CCO:I0015975 ! ifnar2-gnb2l1-4 physical interaction relationship: participates_in CCO:I0016514 ! ikbkg-gnb2l1 physical interaction relationship: participates_in CCO:I0017658 ! st7-gnb2l1-2 physical interaction relationship: participates_in CCO:I0017707 ! ifnar2-gnb2l1-3 physical interaction relationship: participates_in CCO:I0017924 ! ifnar2-gnb2l1-2 physical interaction relationship: participates_in CCO:I0018373 ! ifnar2-gnb2l1-1 physical interaction relationship: participates_in CCO:I0019337 ! st7-gnb2l1-1 physical interaction relationship: transforms_into CCO:B0011923 ! GBLP_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0011924 ! GBLP_HUMAN-Phosphotyrosine228 [Term] id: CCO:B0005740 name: CD4_HUMAN def: "T-cell surface glycoprotein CD4 precursor" [UniProtKB:P01730] synonym: "CD4 antigen" EXACT [UniProtKB:P01730] synonym: "T-cell surface antigen T4/Leu-3" EXACT [UniProtKB:P01730] xref: EMBL:AAA16069.1 xref: EMBL:AAA35572.1 xref: EMBL:AAB51309.1 xref: EMBL:AAH25782.1 xref: EMBL:AAV38594.1 xref: EMBL:AAV38614.1 xref: EMBL:AAY22175.1 xref: UniProtKB:P01730 xref: UniProtKB:Q4ZGK2 xref: UniProtKB:Q5U066 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004278 ! CD4_human relationship: has_function CCO:F0000251 ! glycoprotein binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005649 ! MHC class II protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0018486 ! ccr5-cxcr4-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling relationship: participates_in CCO:P0002981 ! regulation of T cell activation relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation [Term] id: CCO:B0005741 name: RL18_HUMAN def: "60S ribosomal protein L18" [UniProtKB:Q07020] xref: EMBL:AAA16329.1 xref: EMBL:AAH00374.1 xref: EMBL:AAH09708.1 xref: EMBL:AAH21743.1 xref: EMBL:BAB79463.1 xref: UniProtKB:Q07020 xref: UniProtKB:Q8WTZ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005500 ! RPL18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016638 ! map3k1-rpl18 physical interaction relationship: participates_in CCO:I0016819 ! nfkb2-rpl18 physical interaction relationship: transforms_into CCO:B0013886 ! RL18_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0070066 ! RL18_HUMAN-Phosphothreonine158 [Term] id: CCO:B0005742 name: YBOX1_HUMAN def: "Nuclease-sensitive element-binding protein 1" [UniProtKB:P67809] synonym: "CBF-A" EXACT [UniProtKB:P67809] synonym: "CCAAT-binding transcription factor I subunit A" EXACT [UniProtKB:P67809] synonym: "DBPB" EXACT [UniProtKB:P67809] synonym: "DNA-binding protein B" EXACT [UniProtKB:P67809] synonym: "EFI-A" EXACT [UniProtKB:P67809] synonym: "Enhancer factor I subunit A" EXACT [UniProtKB:P67809] synonym: "Y-box transcription factor" EXACT [UniProtKB:P67809] synonym: "Y-box-binding protein 1" EXACT [UniProtKB:P67809] synonym: "YB-1" EXACT [UniProtKB:P67809] xref: EMBL:AAA20871.1 xref: EMBL:AAA35750.1 xref: EMBL:AAA59949.1 xref: EMBL:AAA61308.1 xref: EMBL:AAH02411.1 xref: EMBL:AAH10430.1 xref: EMBL:AAH15208.1 xref: EMBL:AAH38384.1 xref: EMBL:AAH65571.1 xref: EMBL:AAH70084.1 xref: EMBL:AAH71708.1 xref: EMBL:AAH90038.1 xref: EMBL:AAH98435.1 xref: EMBL:AAI06046.1 xref: UniProtKB:P16990 xref: UniProtKB:P16991 xref: UniProtKB:P67809 xref: UniProtKB:Q14972 xref: UniProtKB:Q15325 xref: UniProtKB:Q5FVF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005948 ! YBX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0016846 ! map3k14-nsep1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014723 ! YBOX1_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0014724 ! YBOX1_HUMAN-Phosphotyrosine162 relationship: transforms_into CCO:B0014725 ! YBOX1_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0014726 ! YBOX1_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0014727 ! YBOX1_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0014728 ! YBOX1_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0031385 ! YBOX1_HUMAN-Phosphoserine167 [Term] id: CCO:B0005743 name: MYL6_HUMAN def: "Myosin light polypeptide 6" [UniProtKB:P60660] synonym: "LC17" EXACT [UniProtKB:P60660] synonym: "MLC-3" EXACT [UniProtKB:P60660] synonym: "Myosin light chain 3" EXACT [UniProtKB:P60660] synonym: "Myosin light chain alkali 3" EXACT [UniProtKB:P60660] synonym: "Smooth muscle and nonmuscle myosin light chain alkali 6" EXACT [UniProtKB:P60660] xref: EMBL:AAA20643.1 xref: EMBL:AAA36347.1 xref: EMBL:AAA36348.1 xref: EMBL:AAA59853.1 xref: EMBL:AAA59892.1 xref: EMBL:AAA59893.1 xref: EMBL:AAH06781.2 xref: EMBL:AAH17455.1 xref: EMBL:AAH71661.1 xref: EMBL:BAB62402.1 xref: EMBL:CAG33295.1 xref: UniProtKB:P16475 xref: UniProtKB:P24572 xref: UniProtKB:P24573 xref: UniProtKB:P60660 xref: UniProtKB:Q12790 xref: UniProtKB:Q6IAZ0 xref: UniProtKB:Q6IPY5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005144 ! MYL6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015677 ! ewsr1-myl6 physical interaction relationship: participates_in CCO:I0016443 ! chuk-myl6 physical interaction relationship: participates_in CCO:I0016484 ! ikbke-myl6 physical interaction relationship: participates_in CCO:I0016558 ! ikbkg-myl6 physical interaction relationship: participates_in CCO:I0016756 ! map3k3-myl6 physical interaction relationship: participates_in CCO:I0017031 ! tnfrsf1a-myl6 physical interaction relationship: transforms_into CCO:B0013067 ! MYL6_HUMAN-N-acetylcysteine2 relationship: transforms_into CCO:B0068376 ! MYL6_HUMAN-Phosphotyrosine29 [Term] id: CCO:B0005744 name: RS19_HUMAN def: "40S ribosomal protein S19" [UniProtKB:P39019] xref: EMBL:AAA89070.1 xref: EMBL:AAD13668.1 xref: EMBL:AAH00023.1 xref: EMBL:AAH07615.1 xref: EMBL:AAH18616.1 xref: EMBL:BAA28593.1 xref: UniProtKB:P39019 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005533 ! RPS19_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0016820 ! nfkb2-rps19 physical interaction relationship: participates_in CCO:P0003073 ! positive regulation of cell motility [Term] id: CCO:B0005746 name: RL7_HUMAN def: "60S ribosomal protein L7" [UniProtKB:P18124] xref: EMBL:AAA03081.1 xref: EMBL:AAH06095.1 xref: EMBL:AAH08850.1 xref: EMBL:AAH09599.1 xref: EMBL:AAH71671.1 xref: EMBL:AAH71894.1 xref: EMBL:AAH71895.1 xref: EMBL:AAH87837.1 xref: EMBL:AAI06057.1 xref: EMBL:CAA37139.1 xref: EMBL:CAA41026.1 xref: EMBL:CAA41027.1 xref: EMBL:CAG33054.1 xref: UniProtKB:P18124 xref: UniProtKB:Q15289 xref: UniProtKB:Q3KQU0 xref: UniProtKB:Q5I0X1 xref: UniProtKB:Q6IBM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005509 ! RPL7_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000755 ! large ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016404 ! nfkbib-rpl7 physical interaction relationship: participates_in CCO:I0016627 ! map3k1-rpl7 physical interaction relationship: participates_in CCO:I0016807 ! nfkb2-rpl7 physical interaction relationship: participates_in CCO:I0016971 ! tbk1-rpl7 physical interaction relationship: transforms_into CCO:B0013892 ! RL7_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0013893 ! RL7_HUMAN-Phosphotyrosine139 relationship: transforms_into CCO:B0013894 ! RL7_HUMAN-Phosphotyrosine195 [Term] id: CCO:B0005748 name: RS13_HUMAN def: "40S ribosomal protein S13" [UniProtKB:P62277] xref: EMBL:AAA60283.1 xref: EMBL:AAC15854.1 xref: EMBL:AAH00475.1 xref: EMBL:AAH06772.1 xref: EMBL:AAH29732.1 xref: EMBL:AAH66322.1 xref: EMBL:AAI00033.1 xref: EMBL:BAA13528.1 xref: EMBL:CAA55821.1 xref: UniProtKB:P19116 xref: UniProtKB:P62277 xref: UniProtKB:Q02546 xref: UniProtKB:Q29200 xref: UniProtKB:Q498Y0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005531 ! RPS13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017200 ! nfkb2-rps13 physical interaction relationship: participates_in CCO:I0017230 ! map3k1-rps13 physical interaction relationship: transforms_into CCO:B0013935 ! RS13_HUMAN-Phosphotyrosine38 relationship: transforms_into CCO:B0013936 ! RS13_HUMAN-Phosphotyrosine128 relationship: transforms_into CCO:B0013937 ! RS13_HUMAN-Phosphotyrosine129 relationship: transforms_into CCO:B0036030 ! RS13_HUMAN-Phosphoserine30 [Term] id: CCO:B0005749 name: RS10_HUMAN def: "40S ribosomal protein S10" [UniProtKB:P46783] xref: EMBL:AAA85660.1 xref: EMBL:AAH01032.1 xref: EMBL:AAH01955.1 xref: EMBL:AAH05012.1 xref: EMBL:AAH70235.1 xref: EMBL:AAH71946.1 xref: EMBL:AAH73799.1 xref: EMBL:BAA25817.1 xref: EMBL:CAH73100.1 xref: UniProtKB:P46783 xref: UniProtKB:Q5TZC0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005529 ! RPS10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0016501 ! ikbkg-rps10 physical interaction relationship: participates_in CCO:I0016784 ! nfkb2-rps10 physical interaction relationship: participates_in CCO:I0016860 ! relb-rps10 physical interaction relationship: participates_in CCO:I0019818 ! rps10-pfn2 physical interaction relationship: participates_in CCO:I0020153 ! rps10-myst2 physical interaction relationship: transforms_into CCO:B0013932 ! RS10_HUMAN-Phosphotyrosine12 relationship: transforms_into CCO:B0013933 ! RS10_HUMAN-Phosphoserine146 [Term] id: CCO:B0005750 name: RS9_HUMAN def: "40S ribosomal protein S9" [UniProtKB:P46781] xref: EMBL:AAA85659.1 xref: EMBL:AAH00802.1 xref: EMBL:AAH07410.1 xref: EMBL:AAH07434.1 xref: EMBL:AAH07857.1 xref: EMBL:AAH68055.1 xref: EMBL:AAH71940.1 xref: EMBL:AAH96756.1 xref: EMBL:BAA25816.1 xref: EMBL:BAB79477.1 xref: UniProtKB:P46781 xref: UniProtKB:Q4QRK7 xref: UniProtKB:Q9BVZ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005540 ! RPS9_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016654 ! map3k1-rps9 physical interaction [Term] id: CCO:B0005751 name: RL22_HUMAN def: "60S ribosomal protein L22" [UniProtKB:P35268] synonym: "EAP" EXACT [UniProtKB:P35268] synonym: "EBER-associated protein" EXACT [UniProtKB:P35268] synonym: "Epstein-Barr virus small RNA-associated protein" EXACT [UniProtKB:P35268] synonym: "Heparin-binding protein HBp15" EXACT [UniProtKB:P35268] xref: EMBL:AAH35566.1 xref: EMBL:AAH58887.1 xref: EMBL:AAH66314.1 xref: EMBL:BAA04545.1 xref: EMBL:CAA42007.1 xref: EMBL:CAG33154.1 xref: EMBL:CAI19448.1 xref: EMBL:EAW71518.1 xref: UniProtKB:P35268 xref: UniProtKB:Q6IBD1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005502 ! RPL22_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0020151 ! rpl22-cse1l physical interaction [Term] id: CCO:B0005752 name: EF1B_HUMAN def: "Elongation factor 1-beta" [UniProtKB:P24534] synonym: "EF-1-beta" EXACT [UniProtKB:P24534] xref: EMBL:AAH00211.1 xref: EMBL:AAH04931.1 xref: EMBL:AAH67787.1 xref: EMBL:AAP35742.1 xref: EMBL:AAY15062.1 xref: EMBL:CAA43019.1 xref: EMBL:CAA43063.1 xref: EMBL:CAG33106.1 xref: UniProtKB:P24534 xref: UniProtKB:Q6IBH9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004546 ! EEF1B2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: participates_in CCO:I0019630 ! timp1-eef1b2 physical interaction relationship: participates_in CCO:I0020683 ! ulk2-eef1b2 physical interaction relationship: transforms_into CCO:B0011642 ! EF1B_HUMAN-Phosphothreonine93 relationship: transforms_into CCO:B0011643 ! EF1B_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0011644 ! EF1B_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0011645 ! EF1B_HUMAN-Phosphotyrosine126 relationship: transforms_into CCO:B0011646 ! EF1B_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0011647 ! EF1B_HUMAN-Phosphoserine141 [Term] id: CCO:B0005753 name: SYFB_HUMAN def: "Phenylalanyl-tRNA synthetase beta chain" [UniProtKB:Q9NSD9] synonym: "EC 6.1.1.20" EXACT [UniProtKB:Q9NSD9] synonym: "Phenylalanine--tRNA ligase beta chain" EXACT [UniProtKB:Q9NSD9] synonym: "PheRS" EXACT [UniProtKB:Q9NSD9] xref: EMBL:AAD02220.1 xref: EMBL:AAF29136.1 xref: EMBL:AAH17783.1 xref: EMBL:BAA95608.1 xref: UniProtKB:O95708 xref: UniProtKB:Q9NSD9 xref: UniProtKB:Q9NZZ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006371 ! FARSB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001184 ! phenylalanine-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: transforms_into CCO:B0048402 ! SYFB_HUMAN-Phosphotyrosine63 relationship: transforms_into CCO:B0048403 ! SYFB_HUMAN-Phosphotyrosine72 [Term] id: CCO:B0005754 name: GNAI2_HUMAN def: "Guanine nucleotide-binding protein G(i), alpha-2 subunit" [UniProtKB:P04899] synonym: "Adenylate cyclase-inhibiting G alpha protein" EXACT [UniProtKB:P04899] xref: EMBL:AAA35894.1 xref: EMBL:AAA52556.1 xref: EMBL:AAH12138.1 xref: EMBL:AAH16995.1 xref: EMBL:AAM12620.1 xref: EMBL:CAA28512.1 xref: EMBL:CAA30703.1 xref: UniProtKB:P04899 xref: UniProtKB:Q8IZ71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004710 ! GNAI2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0015967 ! rgs19-gnai2-1 physical interaction relationship: participates_in CCO:I0016711 ! map3k3-gnai2 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:I0020010 ! gnai2-tuba1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0011951 ! GNAI2_HUMAN-ADP-ribosylarginine179 relationship: transforms_into CCO:B0011952 ! GNAI2_HUMAN-ADP-ribosylcysteine352 relationship: transforms_into CCO:B0066485 ! GNAI2_HUMAN-Phosphotyrosine69 [Term] id: CCO:B0005755 name: LPPRC_HUMAN def: "Leucine-rich PPR motif-containing protein, mitochondrial precursor" [UniProtKB:P42704] synonym: "130 kDa leucine-rich protein" EXACT [UniProtKB:P42704] synonym: "GP130" EXACT [UniProtKB:P42704] synonym: "LRP 130" EXACT [UniProtKB:P42704] xref: EMBL:AAA67549.1 xref: EMBL:AAH10282.1 xref: EMBL:AAH26034.1 xref: EMBL:AAH50311.1 xref: EMBL:AAI30286.1 xref: EMBL:AAP41922.1 xref: EMBL:AAY24012.1 xref: EMBL:AAY24043.1 xref: EMBL:BAC86287.1 xref: EMBL:BAF82705.1 xref: UniProtKB:A0PJE3 xref: UniProtKB:A8K1V1 xref: UniProtKB:P42704 xref: UniProtKB:Q53PC0 xref: UniProtKB:Q53QN7 xref: UniProtKB:Q6ZUD8 xref: UniProtKB:Q7Z7A6 xref: UniProtKB:Q96D84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004987 ! LRPPRC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000254 ! nuclear inner membrane relationship: located_in CCO:C0000257 ! nuclear outer membrane relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0016488 ! ikbkg-lrpprc physical interaction relationship: participates_in CCO:I0017172 ! nfkbib-lrpprc physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005756 name: DHRS2_HUMAN def: "Dehydrogenase/reductase SDR family member 2" [UniProtKB:Q13268] synonym: "EC 1.1.-.-" EXACT [UniProtKB:Q13268] synonym: "HEP27 protein" EXACT [UniProtKB:Q13268] synonym: "Protein D" EXACT [UniProtKB:Q13268] xref: EMBL:AAA82048.1 xref: EMBL:AAG33703.1 xref: EMBL:AAH07339.2 xref: UniProtKB:Q13268 xref: UniProtKB:Q9H2R2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004468 ! DHRS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction [Term] id: CCO:B0005758 name: RS7_HUMAN def: "40S ribosomal protein S7" [UniProtKB:P62081] xref: EMBL:AAB00969.1 xref: EMBL:AAH02866.1 xref: EMBL:AAH61901.1 xref: EMBL:AAH71919.1 xref: EMBL:CAA81022.1 xref: UniProtKB:P23821 xref: UniProtKB:P24818 xref: UniProtKB:P62081 xref: UniProtKB:Q6IPH1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005538 ! RPS7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: transforms_into CCO:B0013943 ! RS7_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005760 name: NEP_HUMAN def: "Neprilysin" [UniProtKB:P08473] synonym: "Atriopeptidase" EXACT [UniProtKB:P08473] synonym: "CALLA" EXACT [UniProtKB:P08473] synonym: "CD10 antigen" EXACT [UniProtKB:P08473] synonym: "Common acute lymphocytic leukemia antigen" EXACT [UniProtKB:P08473] synonym: "EC 3.4.24.11" EXACT [UniProtKB:P08473] synonym: "Enkephalinase" EXACT [UniProtKB:P08473] synonym: "NEP" EXACT [UniProtKB:P08473] synonym: "Neutral endopeptidase" EXACT [UniProtKB:P08473] synonym: "Neutral endopeptidase 24.11" EXACT [UniProtKB:P08473] xref: EMBL:AAA51915.1 xref: EMBL:AAA52294.1 xref: EMBL:AAI01633.1 xref: EMBL:AAI01659.1 xref: EMBL:CAA30157.1 xref: EMBL:CAA68752.1 xref: UniProtKB:P08473 xref: UniProtKB:Q3MIX4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005185 ! MME_human relationship: has_function CCO:F0000691 ! neprilysin activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction [Term] id: CCO:B0005761 name: RL7A_HUMAN def: "60S ribosomal protein L7a" [UniProtKB:P62424] synonym: "PLA-X polypeptide" EXACT [UniProtKB:P62424] synonym: "Surfeit locus protein 3" EXACT [UniProtKB:P62424] xref: EMBL:AAA60282.1 xref: EMBL:AAH05128.1 xref: EMBL:AAH21979.1 xref: EMBL:AAH23594.1 xref: EMBL:AAH23624.1 xref: EMBL:AAH71900.1 xref: EMBL:AAH71901.1 xref: EMBL:AAH73802.1 xref: EMBL:CAA29889.1 xref: EMBL:CAA36383.1 xref: EMBL:CAA43925.1 xref: UniProtKB:P11518 xref: UniProtKB:P62424 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005508 ! RPL7A_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001701 ! polysomal ribosome relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0016829 ! nfkb2-rpl7a physical interaction [Term] id: CCO:B0005762 name: RLA0_HUMAN def: "60S acidic ribosomal protein P0" [UniProtKB:P05388] synonym: "L10E" EXACT [UniProtKB:P05388] xref: EMBL:AAA36470.1 xref: EMBL:AAC05176.1 xref: EMBL:AAH00087.1 xref: EMBL:AAH00345.1 xref: EMBL:AAH00752.1 xref: EMBL:AAH01127.1 xref: EMBL:AAH01834.1 xref: EMBL:AAH03655.1 xref: EMBL:AAH05863.1 xref: EMBL:AAH08092.1 xref: EMBL:AAH08594.1 xref: EMBL:AAH09867.1 xref: EMBL:AAH15173.1 xref: EMBL:AAH15690.1 xref: EMBL:BAA25845.1 xref: UniProtKB:P05388 xref: UniProtKB:Q9BVK4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005511 ! RPLP0_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0016534 ! ikbkg-rplp0 physical interaction relationship: transforms_into CCO:B0013896 ! RLA0_HUMAN-Phosphotyrosine24 relationship: transforms_into CCO:B0013897 ! RLA0_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0013898 ! RLA0_HUMAN-Phosphoserine307 [Term] id: CCO:B0005763 name: RS18_HUMAN def: "40S ribosomal protein S18" [UniProtKB:P62269] synonym: "Ke-3" EXACT [UniProtKB:P62269] synonym: "Ke3" EXACT [UniProtKB:P62269] xref: EMBL:CAA20231.1 xref: EMBL:CAB56794.1 xref: UniProtKB:P25232 xref: UniProtKB:P62269 xref: UniProtKB:Q6IPF8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005532 ! RPS18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016792 ! nfkb2-rps18 physical interaction relationship: participates_in CCO:I0016965 ! tbk1-rps18 physical interaction relationship: transforms_into CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 [Term] id: CCO:B0005765 name: VDAC1_HUMAN def: "Voltage-dependent anion-selective channel protein 1" [UniProtKB:P21796] synonym: "hVDAC1" EXACT [UniProtKB:P21796] synonym: "Outer mitochondrial membrane protein porin 1" EXACT [UniProtKB:P21796] synonym: "Plasmalemmal porin" EXACT [UniProtKB:P21796] synonym: "Porin 31HL" EXACT [UniProtKB:P21796] synonym: "Porin 31HM" EXACT [UniProtKB:P21796] synonym: "VDAC-1" EXACT [UniProtKB:P21796] xref: EMBL:AAA61272.1 xref: EMBL:AAC24723.1 xref: EMBL:AAD54939.1 xref: EMBL:AAH08482.1 xref: EMBL:AAH71168.1 xref: EMBL:AAH90042.1 xref: EMBL:CAB58127.1 xref: UniProtKB:P21796 xref: UniProtKB:Q5FVE7 xref: UniProtKB:Q9UIQ5 xref: UniProtKB:Q9UPL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005894 ! VDAC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: participates_in CCO:P0000839 ! apoptotic program relationship: transforms_into CCO:B0014592 ! VDAC1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0014594 ! VDAC1_HUMAN-N6-acetyllysine20 relationship: transforms_into CCO:B0014595 ! VDAC1_HUMAN-N6-acetyllysine28 relationship: transforms_into CCO:B0014596 ! VDAC1_HUMAN-N6-acetyllysine61 relationship: transforms_into CCO:B0014597 ! VDAC1_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0014598 ! VDAC1_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0014599 ! VDAC1_HUMAN-Phosphotyrosine195 relationship: transforms_into CCO:B0014600 ! VDAC1_HUMAN-N6-acetyllysine224 relationship: transforms_into CCO:B0031381 ! VDAC1_HUMAN-Phosphotyrosine67 [Term] id: CCO:B0005767 name: RS12_HUMAN def: "40S ribosomal protein S12" [UniProtKB:P25398] xref: EMBL:BAA25819.1 xref: EMBL:CAA37582.1 xref: UniProtKB:P25398 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005530 ! RPS12_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: transforms_into CCO:B0013934 ! RS12_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005768 name: RS3A_HUMAN def: "40S ribosomal protein S3a" [UniProtKB:P61247] xref: EMBL:AAA35682.1 xref: EMBL:AAA58487.1 xref: EMBL:AAA60290.1 xref: EMBL:AAH00204.1 xref: EMBL:AAH01708.1 xref: EMBL:AAH04981.1 xref: EMBL:AAH06298.1 xref: EMBL:AAH09219.1 xref: EMBL:AAH09404.1 xref: EMBL:AAH17123.1 xref: EMBL:AAH19072.1 xref: EMBL:AAH30161.1 xref: EMBL:AAH70211.1 xref: EMBL:AAH71916.1 xref: EMBL:BAA25814.1 xref: EMBL:CAA60827.1 xref: UniProtKB:P33443 xref: UniProtKB:P49241 xref: UniProtKB:P61247 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005536 ! RPS3A_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: participates_in CCO:I0007844 ! stau-dhx9-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016561 ! ikbkg-rps3a physical interaction relationship: participates_in CCO:I0016830 ! nfkb2-rps3a physical interaction relationship: participates_in CCO:I0016850 ! map3k14-rps3a physical interaction relationship: participates_in CCO:I0018845 ! hspca-rps3a-1 physical interaction relationship: participates_in CCO:I0019547 ! rps3a-hspca physical interaction relationship: participates_in CCO:I0020154 ! rps3a-c20orf31 physical interaction relationship: participates_in CCO:I0020155 ! rps3a-sap18 physical interaction relationship: participates_in CCO:I0020156 ! rps3a-sod2 physical interaction relationship: participates_in CCO:I0020276 ! chn1-rps3a physical interaction relationship: participates_in CCO:I0020522 ! c3orf6-rps3a physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0013941 ! RS3A_HUMAN-Phosphotyrosine256 relationship: transforms_into CCO:B0013942 ! RS3A_HUMAN-Phosphoserine263 [Term] id: CCO:B0005769 name: SSRP1_HUMAN def: "FACT complex subunit SSRP1" [UniProtKB:Q08945] synonym: "Chromatin-specific transcription elongation factor 80 kDa subunit" EXACT [UniProtKB:Q08945] synonym: "Facilitates chromatin transcription complex subunit SSRP1" EXACT [UniProtKB:Q08945] synonym: "FACT 80 kDa subunit" EXACT [UniProtKB:Q08945] synonym: "FACTp80" EXACT [UniProtKB:Q08945] synonym: "hSSRP1" EXACT [UniProtKB:Q08945] synonym: "Recombination signal sequence recognition protein 1" EXACT [UniProtKB:Q08945] synonym: "Structure-specific recognition protein 1" EXACT [UniProtKB:Q08945] synonym: "T160" EXACT [UniProtKB:Q08945] xref: EMBL:AAA58660.1 xref: EMBL:AAH05116.1 xref: EMBL:AAH91486.1 xref: UniProtKB:Q08945 xref: UniProtKB:Q5BJG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005676 ! SSRP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007093 ! srpk1-top2a-1 physical interaction relationship: participates_in CCO:I0007250 ! srpk1-top2a-2 physical interaction relationship: participates_in CCO:I0017317 ! pmscl2-ssrp1 physical interaction relationship: participates_in CCO:I0020379 ! mycbp-ssrp1 physical interaction relationship: participates_in CCO:I0020670 ! ssrp1-robo2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014219 ! SSRP1_HUMAN-Phosphotyrosine311 relationship: transforms_into CCO:B0014220 ! SSRP1_HUMAN-Phosphotyrosine441 relationship: transforms_into CCO:B0014221 ! SSRP1_HUMAN-Phosphoserine444 relationship: transforms_into CCO:B0014222 ! SSRP1_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0014223 ! SSRP1_HUMAN-Phosphotyrosine554 relationship: transforms_into CCO:B0014224 ! SSRP1_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0014225 ! SSRP1_HUMAN-Phosphoserine657 relationship: transforms_into CCO:B0014226 ! SSRP1_HUMAN-Phosphoserine667 relationship: transforms_into CCO:B0014227 ! SSRP1_HUMAN-Phosphoserine668 relationship: transforms_into CCO:B0014228 ! SSRP1_HUMAN-Phosphoserine671 relationship: transforms_into CCO:B0014229 ! SSRP1_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0014230 ! SSRP1_HUMAN-Phosphoserine673 relationship: transforms_into CCO:B0014231 ! SSRP1_HUMAN-Phosphoserine688 relationship: transforms_into CCO:B0041341 ! SSRP1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0070941 ! SSRP1_HUMAN-Phosphothreonine170 relationship: transforms_into CCO:B0070942 ! SSRP1_HUMAN-Phosphoserine437 [Term] id: CCO:B0005770 name: RLA1_HUMAN def: "60S acidic ribosomal protein P1" [UniProtKB:P05386] xref: EMBL:AAA36471.1 xref: EMBL:AAH03369.1 xref: EMBL:AAH07590.1 xref: EMBL:BAB79474.1 xref: UniProtKB:P05386 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005512 ! RPLP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0008045 ! rplp1-ptn physical interaction relationship: participates_in CCO:I0008046 ! rplp1-rif1 physical interaction relationship: participates_in CCO:I0008147 ! pfdn1-rplp1 physical interaction relationship: participates_in CCO:I0019528 ! ascc2-rplp1 physical interaction relationship: participates_in CCO:I0019612 ! rpa2-rplp1 physical interaction relationship: participates_in CCO:I0019817 ! rplp1-g22p1 physical interaction relationship: transforms_into CCO:B0013899 ! RLA1_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0013900 ! RLA1_HUMAN-Phosphotyrosine11 relationship: transforms_into CCO:B0013901 ! RLA1_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0013902 ! RLA1_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0013903 ! RLA1_HUMAN-Phosphoserine104 [Term] id: CCO:B0005771 name: H2B1C_HUMAN def: "Histone H2B type 1-C/E/F/G/I" [UniProtKB:P62807] synonym: "H2B.1 A" EXACT [UniProtKB:P62807] synonym: "H2B.a/g/h/k/l" EXACT [UniProtKB:P62807] synonym: "H2B/a" EXACT [UniProtKB:P62807] synonym: "H2B/g" EXACT [UniProtKB:P62807] synonym: "H2B/h" EXACT [UniProtKB:P62807] synonym: "H2B/k" EXACT [UniProtKB:P62807] synonym: "H2B/l" EXACT [UniProtKB:P62807] xref: EMBL:AAA63189.1 xref: EMBL:AAH82232.1 xref: EMBL:AAH96120.1 xref: EMBL:AAH96122.1 xref: EMBL:AAH96123.1 xref: EMBL:AAI01654.1 xref: EMBL:AAI01656.1 xref: EMBL:AAI01749.1 xref: EMBL:AAI01751.1 xref: EMBL:AAI06900.1 xref: EMBL:AAN06686.1 xref: EMBL:AAN06688.1 xref: EMBL:AAN06689.1 xref: EMBL:AAN06690.1 xref: EMBL:AAN06692.1 xref: EMBL:CAB02541.1 xref: EMBL:CAB02542.1 xref: EMBL:CAB02544.1 xref: EMBL:CAB02545.1 xref: EMBL:CAC03411.1 xref: EMBL:CAC03417.1 xref: EMBL:CAC03420.1 xref: EMBL:CAC04130.1 xref: UniProtKB:P02278 xref: UniProtKB:P62807 xref: UniProtKB:Q3B872 xref: UniProtKB:Q4VB69 xref: UniProtKB:Q93078 xref: UniProtKB:Q93080 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004744 ! HIST1H2BC_human relationship: encoded_by CCO:G0004745 ! HIST1H2BE_human relationship: encoded_by CCO:G0004746 ! HIST1H2BF_human relationship: encoded_by CCO:G0004747 ! HIST1H2BG_human relationship: encoded_by CCO:G0004748 ! HIST1H2BI_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0019276 ! atxn7-trrap-2 acetylation relationship: transforms_into CCO:B0012011 ! H2B1C_HUMAN-N6-acetyllysine6 relationship: transforms_into CCO:B0012012 ! H2B1C_HUMAN-N6-acetyllysine12 relationship: transforms_into CCO:B0012013 ! H2B1C_HUMAN-N6-acetyllysine13 relationship: transforms_into CCO:B0012014 ! H2B1C_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0012015 ! H2B1C_HUMAN-N6-acetyllysine16 relationship: transforms_into CCO:B0012016 ! H2B1C_HUMAN-N6-acetyllysine17 relationship: transforms_into CCO:B0012017 ! H2B1C_HUMAN-N6-acetyllysine21 relationship: transforms_into CCO:B0012018 ! H2B1C_HUMAN-N6-acetyllysine24 relationship: transforms_into CCO:B0012019 ! H2B1C_HUMAN-N6-methyllysine47 relationship: transforms_into CCO:B0012020 ! H2B1C_HUMAN-N6,N6-dimethyllysine58 relationship: transforms_into CCO:B0012021 ! H2B1C_HUMAN-N6-acetyllysine109 relationship: transforms_into CCO:B0012022 ! H2B1C_HUMAN-N6-methyllysine109 [Term] id: CCO:B0005772 name: TBA1A_HUMAN def: "Tubulin alpha-1A chain" [UniProtKB:Q71U36] synonym: "Alpha-tubulin 3" EXACT [UniProtKB:Q71U36] synonym: "Tubulin alpha-3 chain" EXACT [UniProtKB:Q71U36] synonym: "Tubulin B-alpha-1" EXACT [UniProtKB:Q71U36] xref: EMBL:AAA91575.1 xref: EMBL:AAD33871.1 xref: EMBL:AAH06468.1 xref: EMBL:AAH50637.1 xref: EMBL:CAA25855.1 xref: UniProtKB:P04687 xref: UniProtKB:P05209 xref: UniProtKB:Q71U36 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005730 ! TUBA1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007067 ! tubg-mark4-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0016386 ! nfkbia-tuba1 physical interaction relationship: participates_in CCO:I0016421 ! nfkbib-tuba1 physical interaction relationship: participates_in CCO:I0016569 ! ikbkg-tuba1 physical interaction relationship: participates_in CCO:I0016658 ! map3k1-tuba1 physical interaction relationship: participates_in CCO:I0016773 ! map3k3-tuba1 physical interaction relationship: participates_in CCO:I0016838 ! nfkb2-tuba1 physical interaction relationship: transforms_into CCO:B0014308 ! TBA1A_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0014309 ! TBA1A_HUMAN-Phosphotyrosine272 relationship: transforms_into CCO:B0014310 ! TBA1A_HUMAN-Phosphoserine439 [Term] id: CCO:B0005773 name: DDX3X_HUMAN def: "ATP-dependent RNA helicase DDX3X" [UniProtKB:O00571] synonym: "DEAD box protein 3, X-chromosomal" EXACT [UniProtKB:O00571] synonym: "DEAD box, X isoform" EXACT [UniProtKB:O00571] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O00571] synonym: "Helicase-like protein 2" EXACT [UniProtKB:O00571] synonym: "HLP2" EXACT [UniProtKB:O00571] xref: EMBL:AAB95637.1 xref: EMBL:AAC34298.1 xref: EMBL:AAC51829.1 xref: EMBL:AAC51830.1 xref: EMBL:AAH11819.1 xref: UniProtKB:O00571 xref: UniProtKB:O15536 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004458 ! DDX3X_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0017106 ! traf1-ddx3x physical interaction relationship: participates_in CCO:I0017190 ! nfkb2-ddx3x physical interaction relationship: transforms_into CCO:B0011471 ! DDX3X_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0011472 ! DDX3X_HUMAN-Phosphotyrosine69 relationship: transforms_into CCO:B0011473 ! DDX3X_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0011474 ! DDX3X_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0011475 ! DDX3X_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0011476 ! DDX3X_HUMAN-Phosphotyrosine104 relationship: transforms_into CCO:B0011477 ! DDX3X_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0011478 ! DDX3X_HUMAN-Phosphotyrosine343 relationship: transforms_into CCO:B0011479 ! DDX3X_HUMAN-Phosphoserine590 relationship: transforms_into CCO:B0011480 ! DDX3X_HUMAN-Phosphoserine594 [Term] id: CCO:B0005774 name: ROA1_HUMAN def: "Heterogeneous nuclear ribonucleoprotein A1" [UniProtKB:P09651] synonym: "Helix-destabilizing protein" EXACT [UniProtKB:P09651] synonym: "hnRNP core protein A1" EXACT [UniProtKB:P09651] synonym: "Single-strand RNA-binding protein" EXACT [UniProtKB:P09651] xref: EMBL:AAH02355.1 xref: EMBL:AAH09600.1 xref: EMBL:AAH12158.1 xref: EMBL:AAH33714.1 xref: EMBL:AAH52296.1 xref: EMBL:AAH70315.1 xref: EMBL:AAH74502.1 xref: EMBL:AAI03708.1 xref: EMBL:CAA27874.1 xref: EMBL:CAA29922.1 xref: EMBL:CAA31191.1 xref: EMBL:CAA56072.1 xref: UniProtKB:P09651 xref: UniProtKB:Q3MIB7 xref: UniProtKB:Q6PJZ7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006368 ! HNRNPA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0018317 ! ddx48-thoc4-1 direct interaction relationship: transforms_into CCO:B0013909 ! ROA1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0013910 ! ROA1_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0013911 ! ROA1_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0013912 ! ROA1_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0013913 ! ROA1_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0013914 ! ROA1_HUMAN-Phosphothreonine138 relationship: transforms_into CCO:B0013915 ! ROA1_HUMAN-Phosphotyrosine167 relationship: transforms_into CCO:B0013916 ! ROA1_HUMAN-Omega-N-methylated arginine194 relationship: transforms_into CCO:B0013917 ! ROA1_HUMAN-Omega-N-methylated arginine206 relationship: transforms_into CCO:B0013918 ! ROA1_HUMAN-Omega-N-methylated arginine225 relationship: transforms_into CCO:B0013919 ! ROA1_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0013920 ! ROA1_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0013921 ! ROA1_HUMAN-Phosphotyrosine347 relationship: transforms_into CCO:B0013922 ! ROA1_HUMAN-N6-acetyllysine350 [Term] id: CCO:B0005775 name: ACTB_HUMAN def: "Actin, cytoplasmic 1" [UniProtKB:P60709] synonym: "Beta-actin" EXACT [UniProtKB:P60709] xref: EMBL:AAA51567.1 xref: EMBL:AAH01301.1 xref: EMBL:AAH02409.1 xref: EMBL:AAH04251.1 xref: EMBL:AAH12854.1 xref: EMBL:AAH13380.1 xref: EMBL:AAH14861.1 xref: EMBL:AAH16045.1 xref: EMBL:AAP22343.1 xref: EMBL:AAS79319.1 xref: EMBL:CAA23745.1 xref: EMBL:CAA25099.1 xref: EMBL:CAA45026.1 xref: UniProtKB:P02570 xref: UniProtKB:P60709 xref: UniProtKB:P70514 xref: UniProtKB:P99021 xref: UniProtKB:Q11211 xref: UniProtKB:Q64316 xref: UniProtKB:Q75MN2 xref: UniProtKB:Q96B34 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004020 ! ACTB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006019 ! htatip-trrap-1 physical interaction relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007569 ! brg1-baf200-2 physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007876 ! brg1-baf200-1 physical interaction relationship: participates_in CCO:I0008970 ! smad3-actb physical interaction relationship: participates_in CCO:I0008971 ! smad-actb-2 physical interaction relationship: participates_in CCO:I0008974 ! smad3-actb-2 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: transforms_into CCO:B0010440 ! ACTB_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0010441 ! ACTB_HUMAN-N-acetylaspartate2 relationship: transforms_into CCO:B0010442 ! ACTB_HUMAN-Tele-methylhistidine73 relationship: transforms_into CCO:B0010443 ! ACTB_HUMAN-Phosphotyrosine166 relationship: transforms_into CCO:B0010444 ! ACTB_HUMAN-Phosphotyrosine218 relationship: transforms_into CCO:B0010445 ! ACTB_HUMAN-Phosphotyrosine294 relationship: transforms_into CCO:B0041109 ! ACTB_HUMAN-Phosphothreonine318 relationship: transforms_into CCO:B0065393 ! ACTB_HUMAN-Phosphotyrosine53 relationship: transforms_into CCO:B0065394 ! ACTB_HUMAN-Phosphotyrosine91 relationship: transforms_into CCO:B0065395 ! ACTB_HUMAN-Phosphotyrosine198 [Term] id: CCO:B0005776 name: RSSA_HUMAN def: "40S ribosomal protein SA" [UniProtKB:P08865] synonym: "34/67 kDa laminin receptor" EXACT [UniProtKB:P08865] synonym: "Colon carcinoma laminin-binding protein" EXACT [UniProtKB:P08865] synonym: "Laminin receptor 1" EXACT [UniProtKB:P08865] synonym: "LamR" EXACT [UniProtKB:P08865] synonym: "Multidrug resistance-associated protein MGr1-Ag" EXACT [UniProtKB:P08865] synonym: "NEM/1CHD4" EXACT [UniProtKB:P08865] synonym: "p40" EXACT [UniProtKB:P08865] xref: EMBL:AAA36161.1 xref: EMBL:AAA36165.1 xref: EMBL:AAB22299.1 xref: EMBL:AAC50313.1 xref: EMBL:AAC50652.1 xref: EMBL:AAH05391.1 xref: EMBL:AAH08867.1 xref: EMBL:AAH10418.1 xref: EMBL:AAH13827.1 xref: EMBL:AAH34537.1 xref: EMBL:AAH50688.1 xref: EMBL:AAH53370.1 xref: EMBL:AAH62714.1 xref: EMBL:AAH66941.1 xref: EMBL:AAH68062.1 xref: EMBL:AAH70263.1 xref: EMBL:AAH71693.1 xref: EMBL:AAH71968.1 xref: EMBL:AAH71969.1 xref: EMBL:AAH71970.1 xref: EMBL:AAH71971.1 xref: EMBL:AAH73863.1 xref: EMBL:AAI07568.1 xref: EMBL:AAM33304.1 xref: EMBL:AAP35883.1 xref: EMBL:BAA25812.1 xref: EMBL:CAA33112.1 xref: EMBL:CAA43469.1 xref: UniProtKB:P08865 xref: UniProtKB:P11085 xref: UniProtKB:P12030 xref: UniProtKB:Q16471 xref: UniProtKB:Q6IPD1 xref: UniProtKB:Q6IPD2 xref: UniProtKB:Q6NSD1 xref: UniProtKB:Q6NXQ8 xref: UniProtKB:Q86VC0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005543 ! RPSA_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: transforms_into CCO:B0013945 ! RSSA_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0013946 ! RSSA_HUMAN-Phosphotyrosine139 [Term] id: CCO:B0005777 name: VDAC2_HUMAN def: "Voltage-dependent anion-selective channel protein 2" [UniProtKB:P45880] synonym: "hVDAC2" EXACT [UniProtKB:P45880] synonym: "Outer mitochondrial membrane protein porin 2" EXACT [UniProtKB:P45880] synonym: "VDAC-2" EXACT [UniProtKB:P45880] xref: EMBL:AAA60144.1 xref: EMBL:AAA60145.1 xref: EMBL:AAB59457.1 xref: EMBL:AAD40241.1 xref: EMBL:AAH00165.2 xref: EMBL:AAH12883.2 xref: EMBL:AAH72407.1 xref: EMBL:CAG33245.1 xref: EMBL:CAH73106.1 xref: EMBL:CAH73107.1 xref: EMBL:CAH73108.1 xref: EMBL:CAI40910.1 xref: EMBL:CAI40911.1 xref: EMBL:CAI40914.1 xref: UniProtKB:P45880 xref: UniProtKB:Q5VWK1 xref: UniProtKB:Q5VWK3 xref: UniProtKB:Q6IB40 xref: UniProtKB:Q7L3J5 xref: UniProtKB:Q9BWK8 xref: UniProtKB:Q9Y5I6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005895 ! VDAC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007725 ! eef1b1-rps3a-1 physical interaction relationship: transforms_into CCO:B0014601 ! VDAC2_HUMAN-N6-acetyllysine31 relationship: transforms_into CCO:B0014602 ! VDAC2_HUMAN-N6-acetyllysine74 relationship: transforms_into CCO:B0014603 ! VDAC2_HUMAN-Phosphoserine115 relationship: transforms_into CCO:B0014604 ! VDAC2_HUMAN-Phosphotyrosine236 relationship: transforms_into CCO:B0031382 ! VDAC2_HUMAN-Phosphotyrosine206 [Term] id: CCO:B0005778 name: ATPA_HUMAN def: "ATP synthase subunit alpha, mitochondrial precursor" [UniProtKB:P25705] xref: EMBL:AAH03119.1 xref: EMBL:AAH07299.1 xref: EMBL:AAH08028.2 xref: EMBL:AAH11384.1 xref: EMBL:AAH16046.1 xref: EMBL:AAH19310.1 xref: EMBL:AAH39135.2 xref: EMBL:AAH64562.1 xref: EMBL:AAH67385.1 xref: EMBL:AAP35873.1 xref: EMBL:BAA03531.1 xref: EMBL:BAA05672.1 xref: EMBL:CAA41789.1 xref: EMBL:CAA46452.1 xref: UniProtKB:P25705 xref: UniProtKB:Q53XX6 xref: UniProtKB:Q8IXV2 xref: UniProtKB:Q96FB4 xref: UniProtKB:Q96HW2 xref: UniProtKB:Q96IR6 xref: UniProtKB:Q9BTV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004119 ! ATP5A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016699 ! map3k3-atp5a1 physical interaction relationship: participates_in CCO:I0016844 ! map3k14-atp5a1 physical interaction relationship: participates_in CCO:I0016966 ! tbk1-atp5a1 physical interaction relationship: participates_in CCO:I0017001 ! tnfrsf1a-atp5a1 physical interaction relationship: participates_in CCO:I0017042 ! tnfrsf1b-atp5a1 physical interaction relationship: participates_in CCO:I0019190 ! atp12-f1alpha-1 direct interaction relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: transforms_into CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: transforms_into CCO:B0010677 ! ATPA_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0010678 ! ATPA_HUMAN-N6-acetyllysine132 relationship: transforms_into CCO:B0010679 ! ATPA_HUMAN-N6-acetyllysine230 relationship: transforms_into CCO:B0010680 ! ATPA_HUMAN-N6-acetyllysine239 relationship: transforms_into CCO:B0010681 ! ATPA_HUMAN-N6-acetyllysine261 relationship: transforms_into CCO:B0010682 ! ATPA_HUMAN-N6-acetyllysine305 relationship: transforms_into CCO:B0010683 ! ATPA_HUMAN-N6-acetyllysine427 relationship: transforms_into CCO:B0010684 ! ATPA_HUMAN-N6-acetyllysine498 relationship: transforms_into CCO:B0010685 ! ATPA_HUMAN-N6-acetyllysine531 relationship: transforms_into CCO:B0010686 ! ATPA_HUMAN-N6-acetyllysine539 [Term] id: CCO:B0005779 name: ENOA_HUMAN def: "Alpha-enolase" [UniProtKB:P06733] synonym: "2-phospho-D-glycerate hydro-lyase" EXACT [UniProtKB:P06733] synonym: "C-myc promoter-binding protein" EXACT [UniProtKB:P06733] synonym: "EC 4.2.1.11" EXACT [UniProtKB:P06733] synonym: "Enolase 1" EXACT [UniProtKB:P06733] synonym: "MBP-1" EXACT [UniProtKB:P06733] synonym: "MPB-1" EXACT [UniProtKB:P06733] synonym: "NNE" EXACT [UniProtKB:P06733] synonym: "Non-neural enolase" EXACT [UniProtKB:P06733] synonym: "Phosphopyruvate hydratase" EXACT [UniProtKB:P06733] synonym: "Plasminogen-binding protein" EXACT [UniProtKB:P06733] xref: EMBL:AAA35698.1 xref: EMBL:AAA52387.1 xref: EMBL:AAB88178.1 xref: EMBL:AAC39935.1 xref: EMBL:AAH01810.1 xref: EMBL:AAH04458.1 xref: EMBL:AAH09912.1 xref: EMBL:AAH11130.1 xref: EMBL:AAH15641.1 xref: EMBL:AAH21166.2 xref: EMBL:AAH22545.1 xref: EMBL:AAH27725.1 xref: EMBL:AAH50642.1 xref: EMBL:AAP35827.1 xref: EMBL:AAY43128.1 xref: EMBL:CAA34360.1 xref: EMBL:CAA59331.1 xref: EMBL:CAC42425.1 xref: EMBL:CAD97642.1 xref: EMBL:CAH56247.1 xref: UniProtKB:P06733 xref: UniProtKB:P22712 xref: UniProtKB:Q16704 xref: UniProtKB:Q4TUS4 xref: UniProtKB:Q658M5 xref: UniProtKB:Q6GMP2 xref: UniProtKB:Q71V37 xref: UniProtKB:Q7Z3V6 xref: UniProtKB:Q8WU71 xref: UniProtKB:Q9UM55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004565 ! ENO1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001008 ! phosphopyruvate hydratase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001793 ! plasminogen activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000001 ! phosphopyruvate hydratase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0016915 ! ripk2-eno1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0011687 ! ENOA_HUMAN-Phosphotyrosine44 relationship: transforms_into CCO:B0011688 ! ENOA_HUMAN-Phosphotyrosine57 relationship: transforms_into CCO:B0011689 ! ENOA_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0011690 ! ENOA_HUMAN-N6-acetyllysine71 relationship: transforms_into CCO:B0011691 ! ENOA_HUMAN-Phosphothreonine72 relationship: transforms_into CCO:B0011692 ! ENOA_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0011693 ! ENOA_HUMAN-Phosphotyrosine287 [Term] id: CCO:B0005780 name: MED27_HUMAN def: "Mediator of RNA polymerase II transcription subunit 27" [UniProtKB:Q6P2C8] synonym: "Cofactor required for Sp1 transcriptional activation subunit 8" EXACT [UniProtKB:Q6P2C8] synonym: "CRSP complex subunit 8" EXACT [UniProtKB:Q6P2C8] synonym: "Mediator complex subunit 27" EXACT [UniProtKB:Q6P2C8] synonym: "P37 TRAP/SMCC/PC2 subunit" EXACT [UniProtKB:Q6P2C8] synonym: "Transcriptional coactivator CRSP34" EXACT [UniProtKB:Q6P2C8] xref: EMBL:AAD12721.1 xref: EMBL:AAF37290.1 xref: EMBL:AAH02878.1 xref: EMBL:AAH64608.1 xref: EMBL:AAZ13763.1 xref: EMBL:CAH72529.1 xref: EMBL:CAH72530.1 xref: EMBL:CAH72546.1 xref: EMBL:CAH72547.1 xref: EMBL:CAI13386.1 xref: EMBL:CAI13387.1 xref: EMBL:CAI17283.1 xref: EMBL:CAI17284.1 xref: UniProtKB:O95401 xref: UniProtKB:Q4F964 xref: UniProtKB:Q5VTA4 xref: UniProtKB:Q5VTA5 xref: UniProtKB:Q6P2C8 xref: UniProtKB:Q9BU57 xref: UniProtKB:Q9NYR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005070 ! MED27_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0019229 ! surf5-crsp8-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005781 name: MED20_HUMAN def: "Mediator of RNA polymerase II transcription subunit 20" [UniProtKB:Q9H944] synonym: "hTRFP" EXACT [UniProtKB:Q9H944] synonym: "Mediator complex subunit 20" EXACT [UniProtKB:Q9H944] synonym: "TRF-proximal protein homolog" EXACT [UniProtKB:Q9H944] xref: EMBL:AAD16169.1 xref: EMBL:AAH12618.1 xref: EMBL:AAH19866.1 xref: EMBL:AAH32552.1 xref: EMBL:AAH40950.1 xref: EMBL:BAB14399.1 xref: EMBL:CAB43314.1 xref: EMBL:CAI23487.1 xref: UniProtKB:O95821 xref: UniProtKB:Q5T8J4 xref: UniProtKB:Q9H944 xref: UniProtKB:Q9Y429 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005064 ! MED20_human relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000812 ! Srb-mediator complex relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016031 ! ixl-usp49-3 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0018479 ! ixl-usp49-1 physical interaction relationship: participates_in CCO:I0018480 ! ixl-usp49-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005782 name: MED7_HUMAN def: "Mediator of RNA polymerase II transcription subunit 7" [UniProtKB:O43513] synonym: "Activator-recruited cofactor 34 kDa component" EXACT [UniProtKB:O43513] synonym: "ARC34" EXACT [UniProtKB:O43513] synonym: "Cofactor required for Sp1 transcriptional activation subunit 9" EXACT [UniProtKB:O43513] synonym: "CRSP complex subunit 9" EXACT [UniProtKB:O43513] synonym: "hMED7" EXACT [UniProtKB:O43513] synonym: "Mediator complex subunit 7" EXACT [UniProtKB:O43513] synonym: "RNA polymerase transcriptional regulation mediator subunit 7 homolog" EXACT [UniProtKB:O43513] synonym: "Transcriptional coactivator CRSP33" EXACT [UniProtKB:O43513] xref: EMBL:AAC52115.1 xref: EMBL:AAD12720.1 xref: EMBL:AAH05250.1 xref: UniProtKB:O43513 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005077 ! MED7_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0015666 ! crsp9-hgs physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0005783 name: MED21_HUMAN def: "Mediator of RNA polymerase II transcription subunit 21" [UniProtKB:Q13503] synonym: "hSrb7" EXACT [UniProtKB:Q13503] synonym: "Mediator complex subunit 21" EXACT [UniProtKB:Q13503] synonym: "RNA polymerase II holoenzyme component SRB7" EXACT [UniProtKB:Q13503] synonym: "RNAPII complex component SRB7" EXACT [UniProtKB:Q13503] xref: EMBL:AAA98511.1 xref: EMBL:AAB06944.1 xref: EMBL:AAH08380.1 xref: EMBL:CAG33280.1 xref: UniProtKB:Q13503 xref: UniProtKB:Q6IB05 xref: UniProtKB:Q92811 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005065 ! MED21_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005784 name: MED31_HUMAN def: "Mediator of RNA polymerase II transcription subunit 31" [UniProtKB:Q9Y3C7] synonym: "hSOH1" EXACT [UniProtKB:Q9Y3C7] synonym: "Mediator complex subunit 31" EXACT [UniProtKB:Q9Y3C7] synonym: "Mediator complex subunit SOH1" EXACT [UniProtKB:Q9Y3C7] xref: EMBL:AAD34120.1 xref: EMBL:AAH12539.1 xref: UniProtKB:Q9Y3C7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005074 ! MED31_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0008056 ! supt5h-med31 physical interaction relationship: participates_in CCO:I0008077 ! cct7-med31 physical interaction relationship: participates_in CCO:I0008092 ! dleu1-med31 physical interaction relationship: participates_in CCO:I0008103 ! erh-med31 physical interaction relationship: participates_in CCO:I0008142 ! pfdn1-med31 physical interaction relationship: participates_in CCO:I0008235 ! smpd3-med31 physical interaction relationship: participates_in CCO:I0008291 ! pmf1-med31 physical interaction relationship: participates_in CCO:I0016045 ! gadd45g-soh1 physical interaction relationship: participates_in CCO:I0016066 ! hd-soh1 physical interaction relationship: participates_in CCO:I0016067 ! hd-soh1-1 physical interaction relationship: participates_in CCO:I0016068 ! hd-soh1-2 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0018153 ! soh1-hd physical interaction relationship: participates_in CCO:I0018169 ! soh1-gadd45g physical interaction relationship: participates_in CCO:I0019534 ! cpe-med31 physical interaction relationship: participates_in CCO:I0019540 ! rnpc4-med31 physical interaction relationship: participates_in CCO:I0019541 ! rpa2-med31 physical interaction relationship: participates_in CCO:I0019549 ! selenbp1-med31 physical interaction relationship: participates_in CCO:I0019564 ! ascc2-med31 physical interaction relationship: participates_in CCO:I0019587 ! eef1g-med31 physical interaction relationship: participates_in CCO:I0019598 ! lama4-med31 physical interaction relationship: participates_in CCO:I0019600 ! loc51236-med31 physical interaction relationship: participates_in CCO:I0019604 ! pafah1b3-med31 physical interaction relationship: participates_in CCO:I0019609 ! psmd11-med31 physical interaction relationship: participates_in CCO:I0019617 ! serpinb9-med31 physical interaction relationship: participates_in CCO:I0019645 ! agr2-med31 physical interaction relationship: participates_in CCO:I0019711 ! egr2-med31 physical interaction relationship: participates_in CCO:I0019713 ! epn1-med31 physical interaction relationship: participates_in CCO:I0019734 ! hmox2-med31 physical interaction relationship: participates_in CCO:I0019737 ! hrmt1l2-med31 physical interaction relationship: participates_in CCO:I0019739 ! hspb1-med31 physical interaction relationship: participates_in CCO:I0019797 ! pqbp1-med31 physical interaction relationship: participates_in CCO:I0019822 ! sat-med31 physical interaction relationship: participates_in CCO:I0019851 ! tgif-med31 physical interaction relationship: participates_in CCO:I0019872 ! ube2b-med31 physical interaction relationship: participates_in CCO:I0019887 ! znf499-med31 physical interaction relationship: participates_in CCO:I0019937 ! cacnb4-med31 physical interaction relationship: participates_in CCO:I0019974 ! dnm1-med31 physical interaction relationship: participates_in CCO:I0020017 ! gstm4-med31 physical interaction relationship: participates_in CCO:I0020056 ! lypla2-med31 physical interaction relationship: participates_in CCO:I0020057 ! mafg-med31 physical interaction relationship: participates_in CCO:I0020087 ! nfatc2-med31 physical interaction relationship: participates_in CCO:I0020124 ! prei3-med31 physical interaction relationship: participates_in CCO:I0020148 ! rfc5-med31 physical interaction relationship: participates_in CCO:I0020223 ! aes-med31 physical interaction relationship: participates_in CCO:I0020261 ! c7orf19-med31 physical interaction relationship: participates_in CCO:I0020317 ! flj21945-med31 physical interaction relationship: participates_in CCO:I0020333 ! hspb3-med31 physical interaction relationship: participates_in CCO:I0020357 ! tinagl1-med31 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0005785 name: MED17_HUMAN def: "Mediator of RNA polymerase II transcription subunit 17" [UniProtKB:Q9NVC6] synonym: "Activator-recruited cofactor 77 kDa component" EXACT [UniProtKB:Q9NVC6] synonym: "ARC77" EXACT [UniProtKB:Q9NVC6] synonym: "Cofactor required for Sp1 transcriptional activation subunit 6" EXACT [UniProtKB:Q9NVC6] synonym: "CRSP complex subunit 6" EXACT [UniProtKB:Q9NVC6] synonym: "DRIP80" EXACT [UniProtKB:Q9NVC6] synonym: "Mediator complex subunit 17" EXACT [UniProtKB:Q9NVC6] synonym: "Thyroid hormone receptor-associated protein complex 80 kDa component" EXACT [UniProtKB:Q9NVC6] synonym: "Transcriptional coactivator CRSP77" EXACT [UniProtKB:Q9NVC6] synonym: "Trap80" EXACT [UniProtKB:Q9NVC6] synonym: "Vitamin D3 receptor-interacting protein complex 80 kDa component" EXACT [UniProtKB:Q9NVC6] xref: EMBL:AAD12723.1 xref: EMBL:AAD22031.2 xref: EMBL:AAD30856.1 xref: EMBL:AAH21101.1 xref: EMBL:BAA91827.1 xref: EMBL:BAB13973.1 xref: UniProtKB:Q9HA81 xref: UniProtKB:Q9NVC6 xref: UniProtKB:Q9UNP7 xref: UniProtKB:Q9Y2W0 xref: UniProtKB:Q9Y660 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005061 ! MED17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0017849 ! tr-crsp6-1 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0018770 ! med8-nut2-1 physical interaction relationship: participates_in CCO:I0019228 ! surf5-crsp6-1 physical interaction relationship: participates_in CCO:I0019487 ! med8-q9btt4-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0012890 ! MED17_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0012891 ! MED17_HUMAN-Phosphoserine185 [Term] id: CCO:B0005786 name: MED1_HUMAN def: "Mediator of RNA polymerase II transcription subunit 1" [UniProtKB:Q15648] synonym: "Activator-recruited cofactor 205 kDa component" EXACT [UniProtKB:Q15648] synonym: "ARC205" EXACT [UniProtKB:Q15648] synonym: "Mediator complex subunit 1" EXACT [UniProtKB:Q15648] synonym: "p53 regulatory protein RB18A" EXACT [UniProtKB:Q15648] synonym: "PBP" EXACT [UniProtKB:Q15648] synonym: "Peroxisome proliferator-activated receptor-binding protein" EXACT [UniProtKB:Q15648] synonym: "PPAR-binding protein" EXACT [UniProtKB:Q15648] synonym: "Thyroid hormone receptor-associated protein complex 220 kDa component" EXACT [UniProtKB:Q15648] synonym: "Thyroid receptor-interacting protein 2" EXACT [UniProtKB:Q15648] synonym: "Trap220" EXACT [UniProtKB:Q15648] synonym: "TRIP-2" EXACT [UniProtKB:Q15648] synonym: "Vitamin D receptor-interacting protein complex component DRIP205" EXACT [UniProtKB:Q15648] xref: EMBL:AAC39854.1 xref: EMBL:AAC41736.1 xref: EMBL:AAF98352.1 xref: EMBL:AAH06517.1 xref: EMBL:AAH60758.1 xref: EMBL:AAI31784.1 xref: EMBL:CAA73867.1 xref: EMBL:EAW60575.1 xref: UniProtKB:A2RRQ6 xref: UniProtKB:O43810 xref: UniProtKB:O75447 xref: UniProtKB:Q15648 xref: UniProtKB:Q6P9H7 xref: UniProtKB:Q6PK58 xref: UniProtKB:Q9HD39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005063 ! MED1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0017926 ! pparg-pparbp-1 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0012893 ! MED1_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0012894 ! MED1_HUMAN-Phosphoserine770 relationship: transforms_into CCO:B0012895 ! MED1_HUMAN-Phosphoserine771 relationship: transforms_into CCO:B0012896 ! MED1_HUMAN-Phosphoserine772 relationship: transforms_into CCO:B0012897 ! MED1_HUMAN-Phosphoserine774 relationship: transforms_into CCO:B0012898 ! MED1_HUMAN-Phosphoserine795 relationship: transforms_into CCO:B0012899 ! MED1_HUMAN-Phosphothreonine805 relationship: transforms_into CCO:B0012900 ! MED1_HUMAN-Phosphoserine953 relationship: transforms_into CCO:B0012901 ! MED1_HUMAN-Phosphothreonine1032 relationship: transforms_into CCO:B0012902 ! MED1_HUMAN-Phosphothreonine1051 relationship: transforms_into CCO:B0012903 ! MED1_HUMAN-Phosphothreonine1057 relationship: transforms_into CCO:B0012904 ! MED1_HUMAN-Phosphoserine1134 relationship: transforms_into CCO:B0012905 ! MED1_HUMAN-Phosphothreonine1457 relationship: transforms_into CCO:B0068123 ! MED1_HUMAN-Phosphoserine664 relationship: transforms_into CCO:B0068124 ! MED1_HUMAN-Phosphoserine1207 relationship: transforms_into CCO:B0068125 ! MED1_HUMAN-Phosphothreonine1215 relationship: transforms_into CCO:B0068126 ! MED1_HUMAN-Phosphoserine1463 relationship: transforms_into CCO:B0068127 ! MED1_HUMAN-Phosphoserine1479 relationship: transforms_into CCO:B0068128 ! MED1_HUMAN-Phosphoserine1481 relationship: transforms_into CCO:B0068129 ! MED1_HUMAN-Phosphoserine1482 [Term] id: CCO:B0005787 name: MED18_HUMAN def: "Mediator of RNA polymerase II transcription subunit 18" [UniProtKB:Q9BUE0] synonym: "Mediator complex subunit 18" EXACT [UniProtKB:Q9BUE0] synonym: "p28b" EXACT [UniProtKB:Q9BUE0] xref: EMBL:AAH02694.1 xref: EMBL:BAA90910.1 xref: EMBL:BAD06869.1 xref: EMBL:CAI19132.1 xref: EMBL:EAX07699.1 xref: UniProtKB:Q9BUE0 xref: UniProtKB:Q9NXU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005062 ! MED18_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0018480 ! ixl-usp49-2 physical interaction relationship: participates_in CCO:I0018598 ! p28b-p28b-1 physical interaction relationship: participates_in CCO:I0019487 ! med8-q9btt4-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012892 ! MED18_HUMAN-Phosphoserine66 [Term] id: CCO:B0005788 name: CD2L6_HUMAN def: "Cell division cycle 2-like protein kinase 6" [UniProtKB:Q9BWU1] synonym: "CDC2-related protein kinase 6" EXACT [UniProtKB:Q9BWU1] synonym: "Cyclin-dependent kinase 11" EXACT [UniProtKB:Q9BWU1] synonym: "Death-preventing kinase" EXACT [UniProtKB:Q9BWU1] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q9BWU1] xref: EMBL:AAH24247.1 xref: EMBL:AAH37289.1 xref: EMBL:AAK27731.1 xref: EMBL:BAA82980.2 xref: EMBL:CAI20520.1 xref: EMBL:CAI40282.1 xref: EMBL:CAI40286.1 xref: EMBL:CAI41172.1 xref: EMBL:CAI41175.1 xref: UniProtKB:Q5JQZ7 xref: UniProtKB:Q5JR00 xref: UniProtKB:Q8TC78 xref: UniProtKB:Q9BWU1 xref: UniProtKB:Q9UPX2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004276 ! CDC2L6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction [Term] id: CCO:B0005789 name: MED12_HUMAN def: "Mediator of RNA polymerase II transcription subunit 12" [UniProtKB:Q93074] synonym: "Activator-recruited cofactor 240 kDa component" EXACT [UniProtKB:Q93074] synonym: "ARC240" EXACT [UniProtKB:Q93074] synonym: "CAG repeat protein 45" EXACT [UniProtKB:Q93074] synonym: "Mediator complex subunit 12" EXACT [UniProtKB:Q93074] synonym: "OPA-containing protein" EXACT [UniProtKB:Q93074] synonym: "Thyroid hormone receptor-associated protein complex 230 kDa component" EXACT [UniProtKB:Q93074] synonym: "Trap230" EXACT [UniProtKB:Q93074] synonym: "Trinucleotide repeat-containing gene 11 protein" EXACT [UniProtKB:Q93074] xref: EMBL:AAB91440.1 xref: EMBL:AAC83163.1 xref: EMBL:AAD22033.1 xref: EMBL:AAD44162.1 xref: EMBL:BAA12112.1 xref: UniProtKB:O15410 xref: UniProtKB:O75557 xref: UniProtKB:Q93074 xref: UniProtKB:Q9UHV6 xref: UniProtKB:Q9UND7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005056 ! MED12_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0006700 ! cdk8-q9btt4 physical interaction relationship: participates_in CCO:I0006701 ! crsp7-cdk8-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068117 ! MED12_HUMAN-Phosphotyrosine166 relationship: transforms_into CCO:B0068118 ! MED12_HUMAN-Phosphoserine635 [Term] id: CCO:B0005790 name: MED15_HUMAN def: "Mediator of RNA polymerase II transcription subunit 15" [UniProtKB:Q96RN5] synonym: "Activator-recruited cofactor 105 kDa component" EXACT [UniProtKB:Q96RN5] synonym: "ARC105" EXACT [UniProtKB:Q96RN5] synonym: "CTG repeat protein 7a" EXACT [UniProtKB:Q96RN5] synonym: "Mediator complex subunit 15" EXACT [UniProtKB:Q96RN5] synonym: "PC2 glutamine/Q-rich-associated protein" EXACT [UniProtKB:Q96RN5] synonym: "Positive cofactor 2 glutamine/Q-rich-associated protein" EXACT [UniProtKB:Q96RN5] synonym: "TIG-1" EXACT [UniProtKB:Q96RN5] synonym: "TPA-inducible gene 1 protein" EXACT [UniProtKB:Q96RN5] synonym: "Trinucleotide repeat-containing gene 7 protein" EXACT [UniProtKB:Q96RN5] xref: EMBL:AAB91443.1 xref: EMBL:AAC12944.1 xref: EMBL:AAH07529.1 xref: EMBL:AAH13985.1 xref: EMBL:AAK58423.1 xref: EMBL:BAB85034.1 xref: EMBL:BAC03446.1 xref: EMBL:CAG30423.1 xref: UniProtKB:O15413 xref: UniProtKB:Q6IC31 xref: UniProtKB:Q8NF16 xref: UniProtKB:Q96CT0 xref: UniProtKB:Q96IH7 xref: UniProtKB:Q96RN5 xref: UniProtKB:Q9P1T3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005059 ! MED15_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0015327 ! pcqap-plscr1 physical interaction relationship: participates_in CCO:I0017564 ! pcqap-atxn1 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0019916 ! atp5c1-pcqap physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068122 ! MED15_HUMAN-Phosphothreonine603 [Term] id: CCO:B0005791 name: MED16_HUMAN def: "Mediator of RNA polymerase II transcription subunit 16" [UniProtKB:Q9Y2X0] synonym: "Mediator complex subunit 16" EXACT [UniProtKB:Q9Y2X0] synonym: "Thyroid hormone receptor-associated protein 5" EXACT [UniProtKB:Q9Y2X0] synonym: "Thyroid hormone receptor-associated protein complex 95 kDa component" EXACT [UniProtKB:Q9Y2X0] synonym: "Trap95" EXACT [UniProtKB:Q9Y2X0] synonym: "Vitamin D3 receptor-interacting protein complex component DRIP92" EXACT [UniProtKB:Q9Y2X0] xref: EMBL:AAD30032.1 xref: EMBL:AAD31087.1 xref: EMBL:AAH04554.1 xref: EMBL:AAH07853.2 xref: EMBL:AAH11841.1 xref: EMBL:AAH17282.1 xref: UniProtKB:Q6PJT2 xref: UniProtKB:Q96AD4 xref: UniProtKB:Q96I35 xref: UniProtKB:Q9Y2X0 xref: UniProtKB:Q9Y652 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005060 ! MED16_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004420 ! thyroid hormone receptor coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway [Term] id: CCO:B0005792 name: MED6_HUMAN def: "Mediator of RNA polymerase II transcription subunit 6" [UniProtKB:O75586] synonym: "Activator-recruited cofactor 33 kDa component" EXACT [UniProtKB:O75586] synonym: "ARC33" EXACT [UniProtKB:O75586] synonym: "hMed6" EXACT [UniProtKB:O75586] synonym: "Mediator complex subunit 6" EXACT [UniProtKB:O75586] synonym: "Renal carcinoma antigen NY-REN-28" EXACT [UniProtKB:O75586] xref: EMBL:AAB84363.1 xref: EMBL:AAC26869.1 xref: EMBL:AAD42870.1 xref: EMBL:AAH04106.1 xref: EMBL:AAP35477.1 xref: EMBL:BAD96307.1 xref: EMBL:BAD97066.1 xref: EMBL:CAG46498.1 xref: UniProtKB:O15401 xref: UniProtKB:O75586 xref: UniProtKB:Q53FE3 xref: UniProtKB:Q53HJ3 xref: UniProtKB:Q6FHQ4 xref: UniProtKB:Q9BTH1 xref: UniProtKB:Q9UHL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005076 ! MED6_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0019487 ! med8-q9btt4-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005793 name: MED23_HUMAN def: "Mediator of RNA polymerase II transcription subunit 23" [UniProtKB:Q9ULK4] synonym: "Activator-recruited cofactor 130 kDa component" EXACT [UniProtKB:Q9ULK4] synonym: "ARC130" EXACT [UniProtKB:Q9ULK4] synonym: "Cofactor required for Sp1 transcriptional activation subunit 3" EXACT [UniProtKB:Q9ULK4] synonym: "CRSP complex subunit 3" EXACT [UniProtKB:Q9ULK4] synonym: "DRIP130" EXACT [UniProtKB:Q9ULK4] synonym: "hSur-2" EXACT [UniProtKB:Q9ULK4] synonym: "Mediator complex subunit 23" EXACT [UniProtKB:Q9ULK4] synonym: "Transcriptional coactivator CRSP130" EXACT [UniProtKB:Q9ULK4] synonym: "Vitamin D3 receptor-interacting protein complex 130 kDa component" EXACT [UniProtKB:Q9ULK4] xref: EMBL:AAD12724.1 xref: EMBL:AAD30202.1 xref: EMBL:AAD31729.1 xref: EMBL:AAH60759.1 xref: EMBL:BAA86530.1 xref: EMBL:CAB66710.1 xref: EMBL:CAB92072.1 xref: EMBL:CAB92073.1 xref: EMBL:CAI23319.1 xref: EMBL:CAI23320.1 xref: EMBL:EAW48052.1 xref: UniProtKB:O95403 xref: UniProtKB:Q5JWT3 xref: UniProtKB:Q5JWT4 xref: UniProtKB:Q6P9H6 xref: UniProtKB:Q9H0J2 xref: UniProtKB:Q9NTT9 xref: UniProtKB:Q9NTU0 xref: UniProtKB:Q9ULK4 xref: UniProtKB:Q9Y5P7 xref: UniProtKB:Q9Y667 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005067 ! MED23_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0017296 ! crsp3-pum2 physical interaction relationship: participates_in CCO:I0017297 ! crsp3-kiaa0593 physical interaction relationship: participates_in CCO:I0017298 ! crsp3-wdtc1 physical interaction relationship: participates_in CCO:I0017299 ! crsp3-kiaa1041 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005794 name: MED13_HUMAN def: "Mediator of RNA polymerase II transcription subunit 13" [UniProtKB:Q9UHV7] synonym: "Activator-recruited cofactor 250 kDa component" EXACT [UniProtKB:Q9UHV7] synonym: "ARC250" EXACT [UniProtKB:Q9UHV7] synonym: "DRIP 250" EXACT [UniProtKB:Q9UHV7] synonym: "Mediator complex subunit 13" EXACT [UniProtKB:Q9UHV7] synonym: "Thyroid hormone receptor-associated protein 1" EXACT [UniProtKB:Q9UHV7] synonym: "Thyroid hormone receptor-associated protein complex 240 kDa component" EXACT [UniProtKB:Q9UHV7] synonym: "Trap240" EXACT [UniProtKB:Q9UHV7] synonym: "Vitamin D3 receptor-interacting protein complex component DRIP250" EXACT [UniProtKB:Q9UHV7] xref: EMBL:AAD22032.1 xref: EMBL:BAA25519.2 xref: UniProtKB:O60334 xref: UniProtKB:Q9UHV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005057 ! MED13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017297 ! crsp3-kiaa0593 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0012886 ! MED13_HUMAN-Phosphoserine890 relationship: transforms_into CCO:B0012887 ! MED13_HUMAN-Phosphoserine1029 relationship: transforms_into CCO:B0068119 ! MED13_HUMAN-Phosphoserine504 relationship: transforms_into CCO:B0068120 ! MED13_HUMAN-Phosphothreonine519 relationship: transforms_into CCO:B0068121 ! MED13_HUMAN-Phosphoserine537 [Term] id: CCO:B0005795 name: MED22_HUMAN def: "Mediator of RNA polymerase II transcription subunit 22" [UniProtKB:Q15528] synonym: "Mediator complex subunit 22" EXACT [UniProtKB:Q15528] synonym: "Surf-5" EXACT [UniProtKB:Q15528] synonym: "Surfeit locus protein 5" EXACT [UniProtKB:Q15528] xref: EMBL:AAH24225.1 xref: EMBL:AAH40111.1 xref: EMBL:CAA11915.1 xref: EMBL:CAA11916.1 xref: EMBL:CAA12052.1 xref: EMBL:CAA12053.1 xref: EMBL:CAA59462.1 xref: EMBL:CAI12827.1 xref: EMBL:EAW88056.1 xref: UniProtKB:O76072 xref: UniProtKB:Q15528 xref: UniProtKB:Q5T8U0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005066 ! MED22_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0017669 ! surf5-q9p086-2 physical interaction relationship: participates_in CCO:I0017984 ! surf5-q9p086-3 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0019228 ! surf5-crsp6-1 physical interaction relationship: participates_in CCO:I0019229 ! surf5-crsp8-1 physical interaction relationship: participates_in CCO:I0019230 ! surf5-q9p086-1 physical interaction relationship: participates_in CCO:I0019487 ! med8-q9btt4-1 physical interaction relationship: participates_in CCO:I0020327 ! golph2-surf5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005796 name: MED11_HUMAN def: "Mediator of RNA polymerase II transcription subunit 11" [UniProtKB:Q9P086] synonym: "Mediator complex subunit 11" EXACT [UniProtKB:Q9P086] xref: EMBL:AAF28974.1 xref: EMBL:AAH70377.1 xref: EMBL:EAW90417.1 xref: UniProtKB:Q6NS89 xref: UniProtKB:Q9P086 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005055 ! MED11_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017669 ! surf5-q9p086-2 physical interaction relationship: participates_in CCO:I0017984 ! surf5-q9p086-3 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0019230 ! surf5-q9p086-1 physical interaction relationship: participates_in CCO:I0019487 ! med8-q9btt4-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005797 name: MED30_HUMAN def: "Mediator of RNA polymerase II transcription subunit 30" [UniProtKB:Q96HR3] synonym: "Mediator complex subunit 30" EXACT [UniProtKB:Q96HR3] synonym: "Thyroid hormone receptor-associated protein 6" EXACT [UniProtKB:Q96HR3] synonym: "Thyroid hormone receptor-associated protein complex 25 kDa component" EXACT [UniProtKB:Q96HR3] synonym: "TRAP/Mediator complex component TRAP25" EXACT [UniProtKB:Q96HR3] synonym: "Trap25" EXACT [UniProtKB:Q96HR3] xref: EMBL:AAH08226.1 xref: EMBL:AAL89787.1 xref: UniProtKB:Q96HR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005073 ! MED30_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway [Term] id: CCO:B0005798 name: MED8_HUMAN def: "Mediator of RNA polymerase II transcription subunit 8" [UniProtKB:Q96G25] synonym: "Activator-recruited cofactor 32 kDa component" EXACT [UniProtKB:Q96G25] synonym: "ARC32" EXACT [UniProtKB:Q96G25] synonym: "Mediator complex subunit 8" EXACT [UniProtKB:Q96G25] xref: EMBL:AAH10019.3 xref: EMBL:AAH10543.1 xref: EMBL:AAM76709.1 xref: EMBL:CAP58853.1 xref: EMBL:CAP58854.1 xref: UniProtKB:A9IZ91 xref: UniProtKB:A9IZ92 xref: UniProtKB:Q96FQ4 xref: UniProtKB:Q96G25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005078 ! MED8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0006700 ! cdk8-q9btt4 physical interaction relationship: participates_in CCO:I0006701 ! crsp7-cdk8-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0016227 ! tceb1-tceb2-1 physical interaction relationship: participates_in CCO:I0016228 ! tceb1-tceb2-2 physical interaction relationship: participates_in CCO:I0016230 ! ixl-crsp6-1 physical interaction relationship: participates_in CCO:I0016231 ! ixl-crsp6-3 physical interaction relationship: participates_in CCO:I0016232 ! ixl-crsp6-6 physical interaction relationship: participates_in CCO:I0016233 ! q9nwa0-crsp6-2 physical interaction relationship: participates_in CCO:I0016234 ! q9btt4-crsp6-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0017849 ! tr-crsp6-1 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:I0018595 ! tceb2-med8-1 physical interaction relationship: participates_in CCO:I0018596 ! tceb1-med8-1 physical interaction relationship: participates_in CCO:I0018597 ! tceb2-med8-2 physical interaction relationship: participates_in CCO:I0018770 ! med8-nut2-1 physical interaction relationship: participates_in CCO:I0019485 ! tceb1-tceb2-4 physical interaction relationship: participates_in CCO:I0019486 ! tceb1-tceb2-5 physical interaction relationship: participates_in CCO:I0019487 ! med8-q9btt4-1 physical interaction relationship: participates_in CCO:I0019899 ! arrb2-med8 physical interaction relationship: participates_in CCO:I0020110 ! phyhip-med8 physical interaction relationship: participates_in CCO:I0020334 ! hspb3-med8 physical interaction relationship: participates_in CCO:I0020397 ! pex14-med8 physical interaction relationship: participates_in CCO:I0020584 ! loc124402-med8 physical interaction relationship: participates_in CCO:I0020668 ! snta1-med8 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005799 name: MED24_HUMAN def: "Mediator of RNA polymerase II transcription subunit 24" [UniProtKB:O75448] synonym: "Activator-recruited cofactor 100 kDa component" EXACT [UniProtKB:O75448] synonym: "ARC100" EXACT [UniProtKB:O75448] synonym: "Cofactor required for Sp1 transcriptional activation subunit 4" EXACT [UniProtKB:O75448] synonym: "CRSP complex subunit 4" EXACT [UniProtKB:O75448] synonym: "hTRAP100" EXACT [UniProtKB:O75448] synonym: "Mediator complex subunit 24" EXACT [UniProtKB:O75448] synonym: "Thyroid hormone receptor-associated protein 4" EXACT [UniProtKB:O75448] synonym: "Thyroid hormone receptor-associated protein complex 100 kDa component" EXACT [UniProtKB:O75448] synonym: "Trap100" EXACT [UniProtKB:O75448] synonym: "Vitamin D3 receptor-interacting protein complex component DRIP100" EXACT [UniProtKB:O75448] xref: EMBL:AAC39855.1 xref: EMBL:AAF78764.1 xref: EMBL:AAH11375.1 xref: EMBL:BAA09479.2 xref: UniProtKB:O75448 xref: UniProtKB:Q14143 xref: UniProtKB:Q9NNY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005068 ! MED24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: transforms_into CCO:B0012906 ! MED24_HUMAN-Phosphoserine862 relationship: transforms_into CCO:B0012907 ! MED24_HUMAN-Phosphoserine873 [Term] id: CCO:B0005800 name: MED14_HUMAN def: "Mediator of RNA polymerase II transcription subunit 14" [UniProtKB:O60244] synonym: "Activator-recruited cofactor 150 kDa component" EXACT [UniProtKB:O60244] synonym: "ARC150" EXACT [UniProtKB:O60244] synonym: "Cofactor required for Sp1 transcriptional activation subunit 2" EXACT [UniProtKB:O60244] synonym: "CRSP complex subunit 2" EXACT [UniProtKB:O60244] synonym: "DRIP150" EXACT [UniProtKB:O60244] synonym: "hRGR1" EXACT [UniProtKB:O60244] synonym: "Mediator complex subunit 14" EXACT [UniProtKB:O60244] synonym: "Thyroid hormone receptor-associated protein complex 170 kDa component" EXACT [UniProtKB:O60244] synonym: "Transcriptional coactivator CRSP150" EXACT [UniProtKB:O60244] synonym: "Trap170" EXACT [UniProtKB:O60244] synonym: "Vitamin D3 receptor-interacting protein complex 150 kDa component" EXACT [UniProtKB:O60244] xref: EMBL:AAD12725.1 xref: EMBL:AAD24360.1 xref: EMBL:AAG22547.1 xref: EMBL:AAH98377.1 xref: EMBL:AAI32673.1 xref: EMBL:AAI32675.1 xref: EMBL:BAA28626.1 xref: EMBL:BAA28627.1 xref: UniProtKB:O60244 xref: UniProtKB:Q4KMR7 xref: UniProtKB:Q9UNB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005058 ! MED14_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006280 ! q9nwa0-crsp6-1 physical interaction relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:I0017494 ! ixl-crsp6-4 physical interaction relationship: participates_in CCO:I0018144 ! pparbp-crsp2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0012888 ! MED14_HUMAN-Phosphoserine986 relationship: transforms_into CCO:B0012889 ! MED14_HUMAN-Phosphoserine1128 [Term] id: CCO:B0005801 name: MD13L_HUMAN def: "Mediator of RNA polymerase II transcription subunit 13-like" [UniProtKB:Q71F56] synonym: "Mediator complex subunit 13-like" EXACT [UniProtKB:Q71F56] synonym: "Thyroid hormone receptor-associated protein 2" EXACT [UniProtKB:Q71F56] synonym: "Thyroid hormone receptor-associated protein complex 240 kDa component-like" EXACT [UniProtKB:Q71F56] xref: EMBL:AAI30423.1 xref: EMBL:AAQ08182.1 xref: EMBL:AAR08418.1 xref: EMBL:BAA82977.2 xref: EMBL:BAB14697.1 xref: EMBL:CAB61363.1 xref: EMBL:CAB70855.1 xref: EMBL:CAH18186.1 xref: UniProtKB:A1L469 xref: UniProtKB:Q68DN4 xref: UniProtKB:Q71F56 xref: UniProtKB:Q9H8C0 xref: UniProtKB:Q9NSY9 xref: UniProtKB:Q9UFD8 xref: UniProtKB:Q9UPX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005045 ! MED13L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0007071 ! thrap1-q71f56-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012843 ! MD13L_HUMAN-Phosphoserine1643 [Term] id: CCO:B0005802 name: DOCK1_HUMAN def: "Dedicator of cytokinesis protein 1" [UniProtKB:Q14185] synonym: "180 kDa protein downstream of CRK" EXACT [UniProtKB:Q14185] synonym: "DOCK180" EXACT [UniProtKB:Q14185] xref: EMBL:BAA09454.1 xref: EMBL:CAH71463.2 xref: EMBL:CAH71477.2 xref: EMBL:CAH72560.2 xref: EMBL:CAH73231.2 xref: EMBL:CAI15329.2 xref: EMBL:CAI16871.2 xref: EMBL:CAI22477.2 xref: UniProtKB:A9Z1Z5 xref: UniProtKB:Q14185 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004496 ! DOCK1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007074 ! rhog-elmo1-3 physical interaction relationship: participates_in CCO:I0017851 ! elmo1-dock1-1 physical interaction relationship: participates_in CCO:I0017854 ! elmo1-dock1-2 physical interaction relationship: participates_in CCO:I0017855 ! elmo1-dock1-3 physical interaction relationship: participates_in CCO:I0017856 ! elmo1-dock1-4 physical interaction relationship: participates_in CCO:I0017859 ! rac1-dock1-3 physical interaction relationship: participates_in CCO:I0017860 ! elmo1-dock1-5 physical interaction relationship: participates_in CCO:I0018296 ! rac1-elmo1-1 physical interaction relationship: participates_in CCO:I0018297 ! rac1-dock-1 physical interaction relationship: participates_in CCO:I0018591 ! rac1-dock1-4 physical interaction relationship: participates_in CCO:I0019234 ! rac1-dock1-1 physical interaction relationship: participates_in CCO:I0019235 ! rac1-dock1-2 physical interaction relationship: participates_in CCO:I0019238 ! rac1-dock1-5 physical interaction relationship: participates_in CCO:I0019239 ! rac1-dock1-6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0011565 ! DOCK1_HUMAN-Phosphoserine1858 relationship: transforms_into CCO:B0064819 ! DOCK1_HUMAN-Phosphoserine1751 [Term] id: CCO:B0005803 name: TOP2A_HUMAN def: "DNA topoisomerase 2-alpha" [UniProtKB:P11388] synonym: "DNA topoisomerase II, alpha isozyme" EXACT [UniProtKB:P11388] synonym: "EC 5.99.1.3" EXACT [UniProtKB:P11388] xref: EMBL:AAA61209.1 xref: EMBL:AAC16736.1 xref: EMBL:AAC23518.1 xref: EMBL:AAC77388.1 xref: EMBL:AAG13403.1 xref: EMBL:AAG13404.1 xref: EMBL:AAG13405.1 xref: EMBL:CAA09762.1 xref: UniProtKB:P11388 xref: UniProtKB:Q71UN1 xref: UniProtKB:Q71UQ5 xref: UniProtKB:Q9HB24 xref: UniProtKB:Q9HB25 xref: UniProtKB:Q9HB26 xref: UniProtKB:Q9UP44 xref: UniProtKB:Q9UQP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005811 ! TOP2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007093 ! srpk1-top2a-1 physical interaction relationship: participates_in CCO:I0007250 ! srpk1-top2a-2 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0001251 ! apoptotic chromosome condensation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0014427 ! TOP2A_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0014428 ! TOP2A_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0014429 ! TOP2A_HUMAN-Phosphoserine1106 relationship: transforms_into CCO:B0014430 ! TOP2A_HUMAN-Phosphoserine1213 relationship: transforms_into CCO:B0014431 ! TOP2A_HUMAN-Phosphoserine1247 relationship: transforms_into CCO:B0014432 ! TOP2A_HUMAN-Phosphoserine1295 relationship: transforms_into CCO:B0014433 ! TOP2A_HUMAN-Phosphoserine1297 relationship: transforms_into CCO:B0014434 ! TOP2A_HUMAN-Phosphoserine1332 relationship: transforms_into CCO:B0014435 ! TOP2A_HUMAN-Phosphoserine1337 relationship: transforms_into CCO:B0014436 ! TOP2A_HUMAN-Phosphothreonine1343 relationship: transforms_into CCO:B0014437 ! TOP2A_HUMAN-Phosphoserine1351 relationship: transforms_into CCO:B0014438 ! TOP2A_HUMAN-Phosphoserine1354 relationship: transforms_into CCO:B0014439 ! TOP2A_HUMAN-Phosphoserine1374 relationship: transforms_into CCO:B0014440 ! TOP2A_HUMAN-Phosphoserine1377 relationship: transforms_into CCO:B0014441 ! TOP2A_HUMAN-Phosphoserine1387 relationship: transforms_into CCO:B0014442 ! TOP2A_HUMAN-Phosphoserine1393 relationship: transforms_into CCO:B0014443 ! TOP2A_HUMAN-Phosphoserine1469 relationship: transforms_into CCO:B0014444 ! TOP2A_HUMAN-Phosphothreonine1470 relationship: transforms_into CCO:B0014445 ! TOP2A_HUMAN-Phosphoserine1471 relationship: transforms_into CCO:B0014446 ! TOP2A_HUMAN-Phosphoserine1474 relationship: transforms_into CCO:B0014447 ! TOP2A_HUMAN-Phosphoserine1525 relationship: transforms_into CCO:B0052857 ! TOP2A_HUMAN-Phosphoserine1476 relationship: transforms_into CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 [Term] id: CCO:B0005804 name: DHX9_HUMAN def: "ATP-dependent RNA helicase A" [UniProtKB:Q08211] synonym: "DEAH box protein 9" EXACT [UniProtKB:Q08211] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q08211] synonym: "NDH II" EXACT [UniProtKB:Q08211] synonym: "Nuclear DNA helicase II" EXACT [UniProtKB:Q08211] xref: EMBL:AAB48855.1 xref: EMBL:AAH58896.1 xref: EMBL:CAA71668.1 xref: EMBL:CAH71701.1 xref: EMBL:CAI19277.1 xref: UniProtKB:Q08211 xref: UniProtKB:Q5VY62 xref: UniProtKB:Q6PD69 xref: UniProtKB:Q99556 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004470 ! DHX9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007093 ! srpk1-top2a-1 physical interaction relationship: participates_in CCO:I0007250 ! srpk1-top2a-2 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016245 ! rela-dhx9-2 physical interaction relationship: participates_in CCO:I0016637 ! map3k1-dhx9 physical interaction relationship: participates_in CCO:I0016818 ! nfkb2-dhx9 physical interaction relationship: participates_in CCO:I0017675 ! dhx9-rela-1 physical interaction relationship: participates_in CCO:I0018172 ! dhx9-hrmt1l2-1 physical interaction relationship: participates_in CCO:I0018173 ! hrmt1l2-dhx9-1 physical interaction relationship: participates_in CCO:I0018302 ! dhx9-rela-2 physical interaction relationship: participates_in CCO:I0019242 ! rela-dhx9-1 physical interaction relationship: transforms_into CCO:B0011506 ! DHX9_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0011507 ! DHX9_HUMAN-Phosphoserine321 relationship: transforms_into CCO:B0011508 ! DHX9_HUMAN-Phosphotyrosine1234 relationship: transforms_into CCO:B0011509 ! DHX9_HUMAN-Phosphotyrosine1241 [Term] id: CCO:B0005805 name: DDX21_HUMAN def: "Nucleolar RNA helicase 2" [UniProtKB:Q9NR30] synonym: "DEAD box protein 21" EXACT [UniProtKB:Q9NR30] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9NR30] synonym: "Gu-alpha" EXACT [UniProtKB:Q9NR30] synonym: "Nucleolar RNA helicase Gu" EXACT [UniProtKB:Q9NR30] synonym: "Nucleolar RNA helicase II" EXACT [UniProtKB:Q9NR30] synonym: "RH II/Gu" EXACT [UniProtKB:Q9NR30] xref: EMBL:AAB02546.1 xref: EMBL:AAF78930.2 xref: EMBL:AAH08071.2 xref: EMBL:CAH18395.1 xref: EMBL:CAH72377.1 xref: UniProtKB:Q13436 xref: UniProtKB:Q5VX41 xref: UniProtKB:Q68D35 xref: UniProtKB:Q9NR30 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004456 ! DDX21_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007093 ! srpk1-top2a-1 physical interaction relationship: participates_in CCO:I0007250 ! srpk1-top2a-2 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0016796 ! nfkb2-ddx21 physical interaction relationship: transforms_into CCO:B0011463 ! DDX21_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0011464 ! DDX21_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0011465 ! DDX21_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0011466 ! DDX21_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0065930 ! DDX21_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0065931 ! DDX21_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0065932 ! DDX21_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0065933 ! DDX21_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0065934 ! DDX21_HUMAN-Phosphothreonine315 [Term] id: CCO:B0005806 name: OGT1_HUMAN def: "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit" [UniProtKB:O15294] synonym: "EC 2.4.1.-" EXACT [UniProtKB:O15294] synonym: "O-GlcNAc transferase subunit p110" EXACT [UniProtKB:O15294] synonym: "O-linked N-acetylglucosamine transferase 110 kDa subunit" EXACT [UniProtKB:O15294] xref: EMBL:AAB63466.1 xref: EMBL:AAH14434.1 xref: EMBL:AAH38180.1 xref: EMBL:CAB62528.1 xref: EMBL:CAC86127.1 xref: EMBL:CAC86128.1 xref: EMBL:CAC86129.1 xref: EMBL:CAD89970.1 xref: EMBL:CAD97853.1 xref: UniProtKB:O15294 xref: UniProtKB:Q7Z3K0 xref: UniProtKB:Q8WWM8 xref: UniProtKB:Q96CC1 xref: UniProtKB:Q9UG57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005230 ! OGT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007094 ! hcfc1-ogt-1 physical interaction relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0015796 ! ogt-rp13_383k5_2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0041168 ! OGT1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005807 name: SIN3B_HUMAN def: "Paired amphipathic helix protein Sin3b" [UniProtKB:O75182] synonym: "Histone deacetylase complex subunit Sin3b" EXACT [UniProtKB:O75182] synonym: "Transcriptional corepressor Sin3b" EXACT [UniProtKB:O75182] xref: EMBL:AAH05113.1 xref: EMBL:AAH25026.1 xref: EMBL:AAH63531.1 xref: EMBL:AAU01916.1 xref: EMBL:BAA31675.2 xref: UniProtKB:O75182 xref: UniProtKB:Q68GC2 xref: UniProtKB:Q6P4B8 xref: UniProtKB:Q8TB34 xref: UniProtKB:Q9BSC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005615 ! SIN3B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007096 ! hcfc1-sin3b-1 physical interaction relationship: participates_in CCO:I0018640 ! hdac2-rfx5 physical interaction relationship: participates_in CCO:I0018641 ! hdac2-rfx5-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005808 name: THIO_HUMAN def: "Thioredoxin" [UniProtKB:P10599] synonym: "ADF" EXACT [UniProtKB:P10599] synonym: "ATL-derived factor" EXACT [UniProtKB:P10599] synonym: "SASP" EXACT [UniProtKB:P10599] synonym: "Surface-associated sulphydryl protein" EXACT [UniProtKB:P10599] synonym: "Trx" EXACT [UniProtKB:P10599] xref: EMBL:AAA74596.1 xref: EMBL:AAF86466.1 xref: EMBL:AAF87085.1 xref: EMBL:AAG34699.1 xref: EMBL:AAH03377.1 xref: EMBL:AAH54866.1 xref: EMBL:AAN33187.1 xref: EMBL:BAF82197.1 xref: EMBL:CAA38410.1 xref: EMBL:CAA54687.1 xref: EMBL:CAG28593.1 xref: EMBL:CAI14066.1 xref: EMBL:EAW59059.1 xref: UniProtKB:P10599 xref: UniProtKB:Q53X69 xref: UniProtKB:Q96KI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005779 ! TXN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007101 ! trx-jab1-2 physical interaction relationship: participates_in CCO:I0007102 ! jab1-trx physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007252 ! trx-jab1-5 physical interaction relationship: participates_in CCO:I0007253 ! trx-jab1-cdn1b physical interaction relationship: participates_in CCO:I0007425 ! trx-jab1-4 physical interaction relationship: participates_in CCO:I0007563 ! trx-jab1-1 physical interaction relationship: participates_in CCO:I0007863 ! trx-jab1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0014350 ! THIO_HUMAN-N6-acetyllysine94 relationship: transforms_into CCO:B0014351 ! THIO_HUMAN-Phosphothreonine100 [Term] id: CCO:B0005809 name: RBBP7_HUMAN def: "Histone-binding protein RBBP7" [UniProtKB:Q16576] synonym: "Histone acetyltransferase type B subunit 2" EXACT [UniProtKB:Q16576] synonym: "Nucleosome-remodeling factor subunit RBAP46" EXACT [UniProtKB:Q16576] synonym: "RBBP-7" EXACT [UniProtKB:Q16576] synonym: "Retinoblastoma-binding protein 7" EXACT [UniProtKB:Q16576] synonym: "Retinoblastoma-binding protein p46" EXACT [UniProtKB:Q16576] xref: EMBL:AAC50231.1 xref: EMBL:CAA51360.1 xref: UniProtKB:Q16576 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005441 ! RBBP7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007121 ! hcfc1-many-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0019385 ! hdac1-rbbp7-1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0013744 ! RBBP7_HUMAN-N6-acetyllysine119 relationship: transforms_into CCO:B0013745 ! RBBP7_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0013746 ! RBBP7_HUMAN-Phosphothreonine416 relationship: transforms_into CCO:B0069768 ! RBBP7_HUMAN-Phosphoserine354 [Term] id: CCO:B0005810 name: ACTA_HUMAN def: "Actin, aortic smooth muscle" [UniProtKB:P62736] synonym: "Alpha-actin-2" EXACT [UniProtKB:P62736] synonym: "Cell growth-inhibiting gene 46 protein" EXACT [UniProtKB:P62736] xref: EMBL:AAA51577.1 xref: EMBL:AAA60560.1 xref: EMBL:AAH17554.1 xref: EMBL:AAH93052.1 xref: EMBL:AAW29811.1 xref: EMBL:CAA32064.1 xref: EMBL:CAG38756.1 xref: EMBL:CAI13864.1 xref: UniProtKB:P03996 xref: UniProtKB:P04108 xref: UniProtKB:P62736 xref: UniProtKB:Q6FI19 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004019 ! ACTA2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0007125 ! actn2-ttn-6 physical interaction relationship: transforms_into CCO:B0010437 ! ACTA_HUMAN-N-acetylglutamate3 relationship: transforms_into CCO:B0010438 ! ACTA_HUMAN-Tele-methylhistidine75 relationship: transforms_into CCO:B0010439 ! ACTA_HUMAN-Nitrated tyrosine296 [Term] id: CCO:B0005811 name: K2C5_HUMAN def: "Keratin, type II cytoskeletal 5" [UniProtKB:P13647] synonym: "58 kDa cytokeratin" EXACT [UniProtKB:P13647] synonym: "CK-5" EXACT [UniProtKB:P13647] synonym: "Cytokeratin-5" EXACT [UniProtKB:P13647] synonym: "K5" EXACT [UniProtKB:P13647] synonym: "Keratin-5" EXACT [UniProtKB:P13647] xref: EMBL:AAA36143.1 xref: EMBL:AAA36145.1 xref: EMBL:AAF97931.1 xref: EMBL:AAH24292.1 xref: EMBL:AAH42132.1 xref: EMBL:AAH71906.1 xref: EMBL:AAQ81588.1 xref: UniProtKB:P13647 xref: UniProtKB:Q6PI71 xref: UniProtKB:Q6UBJ0 xref: UniProtKB:Q8TA91 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004926 ! KRT5_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0001886 ! keratin filament relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: transforms_into CCO:B0012479 ! K2C5_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0067244 ! K2C5_HUMAN-Phosphotyrosine60 relationship: transforms_into CCO:B0067245 ! K2C5_HUMAN-Phosphotyrosine66 [Term] id: CCO:B0005812 name: FAK1_HUMAN def: "Focal adhesion kinase 1" [UniProtKB:Q05397] synonym: "EC 2.7.10.2" EXACT [UniProtKB:Q05397] synonym: "FADK 1" EXACT [UniProtKB:Q05397] synonym: "pp125FAK" EXACT [UniProtKB:Q05397] synonym: "Protein-tyrosine kinase 2" EXACT [UniProtKB:Q05397] xref: EMBL:AAA35819.1 xref: EMBL:AAA58469.1 xref: UniProtKB:Q05397 xref: UniProtKB:Q14291 xref: UniProtKB:Q9UD85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004606 ! PTK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0018877 ! src-fak1-1 physical interaction relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0011824 ! FAK1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0011825 ! FAK1_HUMAN-Phosphotyrosine397 relationship: transforms_into CCO:B0011826 ! FAK1_HUMAN-Phosphotyrosine407 relationship: transforms_into CCO:B0011827 ! FAK1_HUMAN-Phosphotyrosine576 relationship: transforms_into CCO:B0011828 ! FAK1_HUMAN-Phosphotyrosine577 relationship: transforms_into CCO:B0011829 ! FAK1_HUMAN-Phosphoserine722 relationship: transforms_into CCO:B0011830 ! FAK1_HUMAN-Phosphoserine840 relationship: transforms_into CCO:B0011831 ! FAK1_HUMAN-Phosphoserine843 relationship: transforms_into CCO:B0011832 ! FAK1_HUMAN-Phosphotyrosine861 relationship: transforms_into CCO:B0011833 ! FAK1_HUMAN-Phosphoserine910 relationship: transforms_into CCO:B0011834 ! FAK1_HUMAN-Phosphotyrosine925 relationship: transforms_into CCO:B0066117 ! FAK1_HUMAN-Phosphotyrosine570 [Term] id: CCO:B0005813 name: ADT2_HUMAN def: "ADP/ATP translocase 2" [UniProtKB:P05141] synonym: "Adenine nucleotide translocator 2" EXACT [UniProtKB:P05141] synonym: "ADP,ATP carrier protein 2" EXACT [UniProtKB:P05141] synonym: "ADP,ATP carrier protein, fibroblast isoform" EXACT [UniProtKB:P05141] synonym: "ANT 2" EXACT [UniProtKB:P05141] synonym: "Solute carrier family 25 member 5" EXACT [UniProtKB:P05141] xref: EMBL:AAA35579.1 xref: EMBL:AAA36749.1 xref: EMBL:AAA51737.1 xref: EMBL:AAB39266.1 xref: EMBL:AAB96347.1 xref: EMBL:AAH56160.1 xref: UniProtKB:O43350 xref: UniProtKB:P05141 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004032 ! SLC25A5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:I0016372 ! nfkbia-slc25a5 physical interaction relationship: participates_in CCO:I0016496 ! ikbkg-slc25a5 physical interaction relationship: participates_in CCO:I0016596 ! map3k1-slc25a5 physical interaction relationship: participates_in CCO:I0016676 ! map3k3-slc25a5 physical interaction relationship: participates_in CCO:I0016895 ! ripk1-slc25a5 physical interaction relationship: participates_in CCO:I0016990 ! tnfrsf1a-slc25a5 physical interaction relationship: participates_in CCO:I0017062 ! tradd-slc25a5 physical interaction relationship: participates_in CCO:I0017090 ! traf1-slc25a5 physical interaction relationship: participates_in CCO:I0017116 ! traf2-slc25a5 physical interaction relationship: transforms_into CCO:B0010460 ! ADT2_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0010461 ! ADT2_HUMAN-N6-acetyllysine23 relationship: transforms_into CCO:B0010462 ! ADT2_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0010463 ! ADT2_HUMAN-N6-acetyllysine92 relationship: transforms_into CCO:B0010464 ! ADT2_HUMAN-N6-acetyllysine163 relationship: transforms_into CCO:B0010465 ! ADT2_HUMAN-N6-acetyllysine166 relationship: transforms_into CCO:B0010466 ! ADT2_HUMAN-N6-acetyllysine199 relationship: transforms_into CCO:B0031287 ! ADT2_HUMAN-Phosphotyrosine191 relationship: transforms_into CCO:B0031288 ! ADT2_HUMAN-Phosphotyrosine195 [Term] id: CCO:B0005814 name: HNRPF_HUMAN def: "Heterogeneous nuclear ribonucleoprotein F" [UniProtKB:P52597] synonym: "hnRNP F" EXACT [UniProtKB:P52597] synonym: "Nucleolin-like protein mcs94-1" EXACT [UniProtKB:P52597] xref: EMBL:AAC37584.1 xref: EMBL:AAH01432.1 xref: EMBL:AAH04254.1 xref: EMBL:AAH15580.1 xref: EMBL:AAH16736.1 xref: EMBL:AAI06009.1 xref: EMBL:CAI17066.1 xref: UniProtKB:P52597 xref: UniProtKB:Q5T0N2 xref: UniProtKB:Q96AU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014353 ! HNRNPF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017544 ! hnrpf-a2bp1 physical interaction relationship: participates_in CCO:P0002221 ! regulation of RNA splicing relationship: transforms_into CCO:B0012230 ! HNRPF_HUMAN-N-acetylmethionine2 relationship: transforms_into CCO:B0012231 ! HNRPF_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0012232 ! HNRPF_HUMAN-Phosphotyrosine246 relationship: transforms_into CCO:B0012233 ! HNRPF_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0066864 ! HNRPF_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005815 name: EFNB1_HUMAN def: "Ephrin-B1 precursor" [UniProtKB:P98172] synonym: "ELK ligand" EXACT [UniProtKB:P98172] synonym: "ELK-L" EXACT [UniProtKB:P98172] synonym: "EPH-related receptor tyrosine kinase ligand 2" EXACT [UniProtKB:P98172] synonym: "LERK-2" EXACT [UniProtKB:P98172] xref: EMBL:AAA52369.1 xref: EMBL:AAA53093.1 xref: EMBL:AAB41127.1 xref: EMBL:AAH16649.1 xref: EMBL:AAH52979.1 xref: EMBL:CAB86409.1 xref: UniProtKB:P98172 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004549 ! EFNB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: transforms_into CCO:B0011650 ! EFNB1_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0048252 ! EFNB1_HUMAN-Phosphotyrosine317 [Term] id: CCO:B0005816 name: ATX10_HUMAN def: "Ataxin-10" [UniProtKB:Q9UBB4] synonym: "Brain protein E46 homolog" EXACT [UniProtKB:Q9UBB4] synonym: "Spinocerebellar ataxia type 10 protein" EXACT [UniProtKB:Q9UBB4] xref: EMBL:AAF17219.1 xref: EMBL:AAH07508.1 xref: EMBL:CAB43383.1 xref: EMBL:CAG30454.1 xref: EMBL:CAG33662.1 xref: EMBL:CAI20373.1 xref: EMBL:CAI20419.1 xref: EMBL:CAI41716.1 xref: UniProtKB:O14998 xref: UniProtKB:O15009 xref: UniProtKB:Q6I9X4 xref: UniProtKB:Q9UBB4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004125 ! ATXN10_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction [Term] id: CCO:B0005817 name: K1C14_HUMAN def: "Keratin, type I cytoskeletal 14" [UniProtKB:P02533] synonym: "CK-14" EXACT [UniProtKB:P02533] synonym: "Cytokeratin-14" EXACT [UniProtKB:P02533] synonym: "K14" EXACT [UniProtKB:P02533] synonym: "Keratin-14" EXACT [UniProtKB:P02533] xref: EMBL:AAB59562.1 xref: EMBL:AAF04034.1 xref: EMBL:AAF04035.1 xref: EMBL:AAF04036.1 xref: EMBL:AAF04037.1 xref: EMBL:AAF04038.1 xref: EMBL:AAF04039.1 xref: EMBL:AAH02690.1 xref: EMBL:AAH19097.1 xref: EMBL:AAH42437.1 xref: EMBL:AAH94830.1 xref: EMBL:AAP35850.1 xref: EMBL:BAA05967.1 xref: UniProtKB:P02533 xref: UniProtKB:Q14715 xref: UniProtKB:Q53XY3 xref: UniProtKB:Q9BUE3 xref: UniProtKB:Q9UBN2 xref: UniProtKB:Q9UBN3 xref: UniProtKB:Q9UCY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004920 ! KRT14_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0001886 ! keratin filament relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction [Term] id: CCO:B0005818 name: DNJA3_HUMAN def: "DnaJ homolog subfamily A member 3, mitochondrial precursor" [UniProtKB:Q96EY1] synonym: "DnaJ protein Tid-1" EXACT [UniProtKB:Q96EY1] synonym: "Hepatocellular carcinoma-associated antigen 57" EXACT [UniProtKB:Q96EY1] synonym: "hTid-1" EXACT [UniProtKB:Q96EY1] synonym: "Tumorous imaginal discs protein Tid56 homolog" EXACT [UniProtKB:Q96EY1] xref: EMBL:AAC29066.1 xref: EMBL:AAF66245.1 xref: EMBL:AAH07225.1 xref: EMBL:AAH11855.1 xref: EMBL:AAH12343.1 xref: EMBL:AAH14062.1 xref: EMBL:AAH20248.1 xref: EMBL:AAH30145.1 xref: EMBL:AAH32100.1 xref: EMBL:AAL35323.1 xref: UniProtKB:O75472 xref: UniProtKB:Q8WUJ6 xref: UniProtKB:Q8WXJ3 xref: UniProtKB:Q96D76 xref: UniProtKB:Q96EY1 xref: UniProtKB:Q96IV1 xref: UniProtKB:Q9NYH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004489 ! DNAJA3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007685 ! gfi1b-dnaja3 physical interaction relationship: participates_in CCO:I0015023 ! c1orf117-dnaja3 physical interaction relationship: participates_in CCO:I0015777 ! dnaja3-znf297 physical interaction relationship: participates_in CCO:I0016635 ! map3k1-dnaja3 physical interaction relationship: participates_in CCO:I0016737 ! map3k3-dnaja3 physical interaction relationship: participates_in CCO:I0016816 ! nfkb2-dnaja3 physical interaction relationship: participates_in CCO:I0017023 ! tnfrsf1a-dnaja3 physical interaction relationship: participates_in CCO:I0017047 ! tnfrsf1b-dnaja3 physical interaction relationship: participates_in CCO:I0017574 ! dnaja3-coil physical interaction relationship: participates_in CCO:I0019028 ! atxn1-dnaja3 physical interaction relationship: participates_in CCO:I0019175 ! usp7-dnaja3 physical interaction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0011551 ! DNJA3_HUMAN-Phosphoserine169 [Term] id: CCO:B0005819 name: CBLB_HUMAN def: "E3 ubiquitin-protein ligase CBL-B" [UniProtKB:Q13191] synonym: "Casitas B-lineage lymphoma proto-oncogene b" EXACT [UniProtKB:Q13191] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q13191] synonym: "RING finger protein 56" EXACT [UniProtKB:Q13191] synonym: "SH3-binding protein CBL-B" EXACT [UniProtKB:Q13191] synonym: "Signal transduction protein CBL-B" EXACT [UniProtKB:Q13191] xref: EMBL:AAB09291.1 xref: EMBL:AAB09292.1 xref: EMBL:AAB09293.1 xref: EMBL:AAH32851.1 xref: EMBL:BAE45748.1 xref: EMBL:CAH56175.1 xref: UniProtKB:Q13191 xref: UniProtKB:Q13192 xref: UniProtKB:Q13193 xref: UniProtKB:Q3LIC0 xref: UniProtKB:Q63Z43 xref: UniProtKB:Q8IVC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004227 ! CBLB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0010939 ! CBLB_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0010940 ! CBLB_HUMAN-Phosphoserine484 relationship: transforms_into CCO:B0010941 ! CBLB_HUMAN-Phosphotyrosine665 relationship: transforms_into CCO:B0010942 ! CBLB_HUMAN-Phosphotyrosine709 relationship: transforms_into CCO:B0010943 ! CBLB_HUMAN-Phosphotyrosine889 relationship: transforms_into CCO:B0064090 ! CBLB_HUMAN-Phosphoserine521 relationship: transforms_into CCO:B0064091 ! CBLB_HUMAN-Phosphoserine525 relationship: transforms_into CCO:B0064092 ! CBLB_HUMAN-Phosphoserine529 [Term] id: CCO:B0005820 name: PEX19_HUMAN def: "Peroxisomal biogenesis factor 19" [UniProtKB:P40855] synonym: "33 kDa housekeeping protein" EXACT [UniProtKB:P40855] synonym: "Peroxin-19" EXACT [UniProtKB:P40855] synonym: "Peroxisomal farnesylated protein" EXACT [UniProtKB:P40855] xref: EMBL:AAH00496.1 xref: EMBL:AAP35525.1 xref: EMBL:BAA76291.1 xref: EMBL:BAB93469.1 xref: EMBL:CAA53225.1 xref: EMBL:CAA70257.1 xref: UniProtKB:P40855 xref: UniProtKB:Q8NI97 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005299 ! PEX19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0015936 ! pex19-pex14-1 physical interaction relationship: participates_in CCO:I0019379 ! pex19-pex11b-1 physical interaction relationship: transforms_into CCO:B0013487 ! PEX19_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0013488 ! PEX19_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0013489 ! PEX19_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0013490 ! PEX19_HUMAN-Phosphoserine147 relationship: transforms_into CCO:B0013491 ! PEX19_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0013492 ! PEX19_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0013493 ! PEX19_HUMAN-Phosphoserine184 [Term] id: CCO:B0005821 name: K2C6A_HUMAN def: "Keratin, type II cytoskeletal 6A" [UniProtKB:P02538] synonym: "Allergen Hom s 5" EXACT [UniProtKB:P02538] synonym: "CK 6A" EXACT [UniProtKB:P02538] synonym: "CK 6D" EXACT [UniProtKB:P02538] synonym: "Cytokeratin-6A" EXACT [UniProtKB:P02538] synonym: "Cytokeratin-6D" EXACT [UniProtKB:P02538] synonym: "K6a keratin" EXACT [UniProtKB:P02538] xref: EMBL:AAB60696.1 xref: EMBL:AAC41767.1 xref: EMBL:AAH08807.1 xref: EMBL:AAH14152.1 xref: EMBL:AAH69269.1 xref: EMBL:AAI25059.1 xref: EMBL:AAP35545.1 xref: EMBL:CAA24760.1 xref: UniProtKB:P02538 xref: UniProtKB:P48667 xref: UniProtKB:Q08AR4 xref: UniProtKB:Q6NT67 xref: UniProtKB:Q96CL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004927 ! KRT6A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0015399 ! krt15-krt6a physical interaction relationship: participates_in CCO:I0015426 ! krt17-krt6a physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0012480 ! K2C6A_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0041308 ! K2C6A_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005822 name: HSP71_HUMAN def: "Heat shock 70 kDa protein 1" [UniProtKB:P08107] synonym: "HSP70-1/HSP70-2" EXACT [UniProtKB:P08107] synonym: "HSP70.1" EXACT [UniProtKB:P08107] xref: EMBL:AAA52697.1 xref: EMBL:AAA59844.1 xref: EMBL:AAA59845.1 xref: EMBL:AAA63226.1 xref: EMBL:AAA63227.1 xref: EMBL:AAD21815.1 xref: EMBL:AAD21816.1 xref: EMBL:AAH02453.1 xref: EMBL:AAH09322.1 xref: EMBL:AAH18740.1 xref: EMBL:AAH57397.1 xref: EMBL:AAH63507.1 xref: EMBL:ABD48956.1 xref: EMBL:ABD96830.1 xref: EMBL:BAB63299.1 xref: EMBL:BAB63300.1 xref: EMBL:CAA28381.1 xref: EMBL:CAA28382.1 xref: EMBL:CAI17737.1 xref: EMBL:CAI17738.1 xref: EMBL:CAI18216.1 xref: EMBL:CAI18217.1 xref: EMBL:CAI18464.1 xref: EMBL:CAI18466.1 xref: UniProtKB:P08107 xref: UniProtKB:P19790 xref: UniProtKB:Q5JQI4 xref: UniProtKB:Q5SP17 xref: UniProtKB:Q9UQL9 xref: UniProtKB:Q9UQM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004834 ! HSPA1A_human relationship: encoded_by CCO:G0004835 ! HSPA1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007131 ! terf2ip-rad50 physical interaction relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0018256 ! hspa1a-hspbp1-1 direct interaction relationship: participates_in CCO:I0019042 ! atxn1-hspa1a physical interaction relationship: participates_in CCO:I0019509 ! tssk6-hspcb-1 physical interaction relationship: participates_in CCO:I0020071 ! mgc5352-hspa1a physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0012274 ! HSP71_HUMAN-Phosphotyrosine611 relationship: transforms_into CCO:B0012275 ! HSP71_HUMAN-Phosphoserine631 relationship: transforms_into CCO:B0066924 ! HSP71_HUMAN-Phosphotyrosine41 [Term] id: CCO:B0005823 name: K2C1_HUMAN def: "Keratin, type II cytoskeletal 1" [UniProtKB:P04264] synonym: "67 kDa cytokeratin" EXACT [UniProtKB:P04264] synonym: "CK-1" EXACT [UniProtKB:P04264] synonym: "Cytokeratin-1" EXACT [UniProtKB:P04264] synonym: "Hair alpha protein" EXACT [UniProtKB:P04264] synonym: "K1" EXACT [UniProtKB:P04264] synonym: "Keratin-1" EXACT [UniProtKB:P04264] xref: EMBL:AAA36153.1 xref: EMBL:AAB47721.1 xref: EMBL:AAF60327.1 xref: EMBL:AAG41947.1 xref: EMBL:AAH63697.1 xref: UniProtKB:P04264 xref: UniProtKB:Q14720 xref: UniProtKB:Q6GSJ0 xref: UniProtKB:Q9H298 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004925 ! KRT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007447 ! apc-ctbb1 physical interaction relationship: participates_in CCO:I0016588 ! tank-krt1 physical interaction relationship: participates_in CCO:I0018579 ! mapk11-sp1-1 physical interaction relationship: transforms_into CCO:B0012475 ! K2C1_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0012476 ! K2C1_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0012477 ! K2C1_HUMAN-Phosphotyrosine295 relationship: transforms_into CCO:B0012478 ! K2C1_HUMAN-Phosphothreonine297 [Term] id: CCO:B0005824 name: CTNA1_HUMAN def: "Catenin alpha-1" [UniProtKB:P35221] synonym: "Alpha E-catenin" EXACT [UniProtKB:P35221] synonym: "Cadherin-associated protein" EXACT [UniProtKB:P35221] synonym: "NY-REN-13 antigen" EXACT [UniProtKB:P35221] xref: EMBL:AAA18949.1 xref: EMBL:AAA35502.1 xref: EMBL:AAA86430.1 xref: EMBL:AAC99459.1 xref: EMBL:AAH00385.1 xref: EMBL:AAW56940.1 xref: EMBL:BAA02979.1 xref: EMBL:BAA03530.1 xref: UniProtKB:P35221 xref: UniProtKB:Q12795 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004416 ! CTNNA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006539 ! cdh1-ctnna1-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000794 ! negative regulation of neuroblast proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002587 ! positive regulation of smoothened signaling pathway relationship: transforms_into CCO:B0011367 ! CTNA1_HUMAN-Phosphoserine641 relationship: transforms_into CCO:B0011368 ! CTNA1_HUMAN-Phosphoserine652 relationship: transforms_into CCO:B0011369 ! CTNA1_HUMAN-Phosphothreonine654 relationship: transforms_into CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: transforms_into CCO:B0011371 ! CTNA1_HUMAN-Phosphothreonine658 relationship: transforms_into CCO:B0048210 ! CTNA1_HUMAN-Phosphothreonine645 relationship: transforms_into CCO:B0064574 ! CTNA1_HUMAN-Phosphotyrosine177 relationship: transforms_into CCO:B0064575 ! CTNA1_HUMAN-Phosphotyrosine619 [Term] id: CCO:B0005825 name: S10AB_HUMAN def: "Protein S100-A11" [UniProtKB:P31949] synonym: "Calgizzarin" EXACT [UniProtKB:P31949] synonym: "MLN 70" EXACT [UniProtKB:P31949] synonym: "Protein S100C" EXACT [UniProtKB:P31949] synonym: "S100 calcium-binding protein A11" EXACT [UniProtKB:P31949] xref: EMBL:AAH01410.1 xref: EMBL:AAH14354.1 xref: EMBL:AAP88914.1 xref: EMBL:BAA07597.1 xref: EMBL:BAA08354.1 xref: EMBL:BAA23325.1 xref: EMBL:CAA56492.1 xref: EMBL:CAH72895.1 xref: UniProtKB:P31949 xref: UniProtKB:Q5VTK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005555 ! S100A11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007148 ! s100b-s100a11-s100a6 colocalization relationship: participates_in CCO:I0015972 ! s100b-s100a11-1 physical interaction relationship: participates_in CCO:I0016193 ! s100b-s100a11-3 physical interaction relationship: participates_in CCO:I0017919 ! s100a11-s100a11-1 physical interaction relationship: participates_in CCO:I0017920 ! s100b-s100a11-2 physical interaction relationship: participates_in CCO:I0017921 ! s100a11-s100b-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0013950 ! S10AB_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0070274 ! S10AB_HUMAN-Phosphothreonine10 relationship: transforms_into CCO:B0070275 ! S10AB_HUMAN-Phosphotyrosine30 relationship: transforms_into CCO:B0070276 ! S10AB_HUMAN-Phosphotyrosine32 [Term] id: CCO:B0005826 name: PKP2_HUMAN def: "Plakophilin-2" [UniProtKB:Q99959] xref: EMBL:CAA66264.1 xref: EMBL:CAA66265.1 xref: UniProtKB:Q99959 xref: UniProtKB:Q99960 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005330 ! PKP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: transforms_into CCO:B0013551 ! PKP2_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0013552 ! PKP2_HUMAN-Phosphoserine169 relationship: transforms_into CCO:B0069375 ! PKP2_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0069376 ! PKP2_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0069377 ! PKP2_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0069378 ! PKP2_HUMAN-Phosphotyrosine168 relationship: transforms_into CCO:B0069379 ! PKP2_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0069380 ! PKP2_HUMAN-Phosphoserine329 [Term] id: CCO:B0005827 name: ATPB_HUMAN def: "ATP synthase subunit beta, mitochondrial precursor" [UniProtKB:P06576] synonym: "EC 3.6.3.14" EXACT [UniProtKB:P06576] xref: EMBL:AAA51808.1 xref: EMBL:AAA51809.1 xref: EMBL:AAH16512.1 xref: EMBL:BAA00016.1 xref: EMBL:CAA27246.1 xref: EMBL:CAA29095.1 xref: UniProtKB:P06576 xref: UniProtKB:Q14283 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004120 ! ATP5B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0008808 ! psme3-atp5b physical interaction relationship: participates_in CCO:I0016550 ! ikbkg-atp5b physical interaction relationship: transforms_into CCO:B0010687 ! ATPB_HUMAN-N6-acetyllysine133 relationship: transforms_into CCO:B0010688 ! ATPB_HUMAN-N6-acetyllysine259 relationship: transforms_into CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: transforms_into CCO:B0010690 ! ATPB_HUMAN-Phosphoserine529 [Term] id: CCO:B0005828 name: GRP75_HUMAN def: "Stress-70 protein, mitochondrial precursor" [UniProtKB:P38646] synonym: "75 kDa glucose-regulated protein" EXACT [UniProtKB:P38646] synonym: "GRP 75" EXACT [UniProtKB:P38646] synonym: "Heat shock 70 kDa protein 9" EXACT [UniProtKB:P38646] synonym: "Mortalin" EXACT [UniProtKB:P38646] synonym: "MOT" EXACT [UniProtKB:P38646] synonym: "PBP74" EXACT [UniProtKB:P38646] synonym: "Peptide-binding protein 74" EXACT [UniProtKB:P38646] xref: EMBL:AAA67526.1 xref: EMBL:AAH00478.1 xref: EMBL:AAH24034.1 xref: EMBL:ABF50973.1 xref: EMBL:BAD96478.1 xref: EMBL:BAG37618.1 xref: EMBL:EAW62129.1 xref: UniProtKB:B2RCM1 xref: UniProtKB:P30036 xref: UniProtKB:P31932 xref: UniProtKB:P38646 xref: UniProtKB:Q1HB43 xref: UniProtKB:Q53H23 xref: UniProtKB:Q6GU03 xref: UniProtKB:Q9BWB7 xref: UniProtKB:Q9UC56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004731 ! HSPA9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016342 ! map3k8-hspa9b physical interaction relationship: participates_in CCO:I0016351 ! rel-hspa9b physical interaction relationship: participates_in CCO:I0016373 ! nfkbia-hspa9b physical interaction relationship: participates_in CCO:I0016392 ! nfkbib-hspa9b physical interaction relationship: participates_in CCO:I0016423 ! nfkbie-hspa9b physical interaction relationship: participates_in CCO:I0016434 ! chuk-hspa9b physical interaction relationship: participates_in CCO:I0016452 ! ikbkb-hspa9b physical interaction relationship: participates_in CCO:I0016467 ! ikbke-hspa9b physical interaction relationship: participates_in CCO:I0016498 ! ikbkg-hspa9b physical interaction relationship: participates_in CCO:I0016574 ! tank-hspa9b physical interaction relationship: participates_in CCO:I0016598 ! map3k1-hspa9b physical interaction relationship: participates_in CCO:I0016781 ! nfkb2-hspa9b-1 physical interaction relationship: participates_in CCO:I0016840 ! map3k14-hspa9b physical interaction relationship: participates_in CCO:I0016858 ! relb-hspa9b physical interaction relationship: participates_in CCO:I0016896 ! ripk1-hspa9b physical interaction relationship: participates_in CCO:I0016925 ! map3k7ip1-hspa9b physical interaction relationship: participates_in CCO:I0016939 ! q9nyj8-hspa9b physical interaction relationship: participates_in CCO:I0016961 ! tbk1-hspa9b physical interaction relationship: participates_in CCO:I0016992 ! tnfrsf1a-hspa9b physical interaction relationship: participates_in CCO:I0017039 ! tnfrsf1b-hspa9b physical interaction relationship: participates_in CCO:I0017091 ! traf1-hspa9b physical interaction relationship: participates_in CCO:I0017117 ! traf2-hspa9b physical interaction relationship: participates_in CCO:I0017137 ! traf6-hspa9b physical interaction relationship: participates_in CCO:I0017237 ! map3k3-hspa9b physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0011982 ! GRP75_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0011983 ! GRP75_HUMAN-N6-acetyllysine288 relationship: transforms_into CCO:B0011984 ! GRP75_HUMAN-N6-acetyllysine300 relationship: transforms_into CCO:B0066632 ! GRP75_HUMAN-Phosphotyrosine568 [Term] id: CCO:B0005829 name: CKAP4_HUMAN def: "Cytoskeleton-associated protein 4" [UniProtKB:Q07065] synonym: "63 kDa membrane protein" EXACT [UniProtKB:Q07065] synonym: "p63" EXACT [UniProtKB:Q07065] xref: EMBL:AAH82972.1 xref: EMBL:AAH94824.1 xref: EMBL:BAD97283.1 xref: EMBL:CAA49535.2 xref: UniProtKB:Q07065 xref: UniProtKB:Q504S5 xref: UniProtKB:Q53ES6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004362 ! CKAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0020242 ! ascc2-ckap4 physical interaction relationship: transforms_into CCO:B0011242 ! CKAP4_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0064367 ! CKAP4_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0064368 ! CKAP4_HUMAN-Phosphothreonine316 relationship: transforms_into CCO:B0064369 ! CKAP4_HUMAN-Phosphoserine330 [Term] id: CCO:B0005830 name: FHL2_HUMAN def: "Four and a half LIM domains protein 2" [UniProtKB:Q14192] synonym: "FHL-2" EXACT [UniProtKB:Q14192] synonym: "LIM domain protein DRAL" EXACT [UniProtKB:Q14192] synonym: "Skeletal muscle LIM-protein 3" EXACT [UniProtKB:Q14192] synonym: "SLIM 3" EXACT [UniProtKB:Q14192] xref: EMBL:AAA85333.1 xref: EMBL:AAC50794.1 xref: EMBL:AAC52073.1 xref: EMBL:AAH14397.1 xref: EMBL:BAA92253.1 xref: UniProtKB:Q13229 xref: UniProtKB:Q13644 xref: UniProtKB:Q14192 xref: UniProtKB:Q9P294 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004646 ! FHL2_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0019035 ! atxn1-fhl2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066186 ! FHL2_HUMAN-Phosphoserine238 [Term] id: CCO:B0005831 name: EF1A1_HUMAN def: "Elongation factor 1-alpha 1" [UniProtKB:P68104] synonym: "eEF1A-1" EXACT [UniProtKB:P68104] synonym: "EF-1-alpha-1" EXACT [UniProtKB:P68104] synonym: "EF-Tu" EXACT [UniProtKB:P68104] synonym: "Elongation factor 1 A-1" EXACT [UniProtKB:P68104] synonym: "Elongation factor Tu" EXACT [UniProtKB:P68104] synonym: "Leukocyte receptor cluster member 7" EXACT [UniProtKB:P68104] xref: EMBL:AAA52343.1 xref: EMBL:AAA52367.1 xref: EMBL:AAH08587.1 xref: EMBL:AAH09733.1 xref: EMBL:AAH09875.1 xref: EMBL:AAH10735.1 xref: EMBL:AAH12891.1 xref: EMBL:AAH14224.1 xref: EMBL:AAH18150.1 xref: EMBL:AAH18641.1 xref: EMBL:AAH19669.1 xref: EMBL:AAH21686.1 xref: EMBL:AAH28674.1 xref: EMBL:AAH38339.1 xref: EMBL:AAH57391.1 xref: EMBL:AAH66893.1 xref: EMBL:AAH72385.1 xref: EMBL:AAH82268.1 xref: EMBL:AAK95378.1 xref: EMBL:CAA27245.1 xref: EMBL:CAA27325.1 xref: EMBL:CAA34756.1 xref: UniProtKB:P04719 xref: UniProtKB:P04720 xref: UniProtKB:P68104 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004545 ! EEF1A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0007985 ! dleu1-eef1a1 physical interaction relationship: participates_in CCO:I0007998 ! axin1-eef1a1 physical interaction relationship: participates_in CCO:I0008006 ! cks2-eef1a1 physical interaction relationship: participates_in CCO:I0008130 ! mad2l1bp-eef1a1 physical interaction relationship: participates_in CCO:I0008178 ! tp53bp2-eef1a1 physical interaction relationship: participates_in CCO:I0008202 ! brms1-eef1a1 physical interaction relationship: participates_in CCO:I0008270 ! mnat1-eef1a1 physical interaction relationship: participates_in CCO:I0016038 ! gadd45g-eef1a1 physical interaction relationship: participates_in CCO:I0019530 ! ccl18-eef1a1 physical interaction relationship: participates_in CCO:I0019538 ! hspe1-eef1a1 physical interaction relationship: participates_in CCO:I0019539 ! lama4-eef1a1 physical interaction relationship: participates_in CCO:I0019543 ! rpa2-eef1a1 physical interaction relationship: participates_in CCO:I0019551 ! serpinb9-eef1a1 physical interaction relationship: participates_in CCO:I0019556 ! znf24-eef1a1 physical interaction relationship: participates_in CCO:I0019583 ! dncl1-eef1a1 physical interaction relationship: participates_in CCO:I0019585 ! eef1a1-pfn2 physical interaction relationship: participates_in CCO:I0019589 ! eif3s5-eef1a1 physical interaction relationship: participates_in CCO:I0019628 ! taf9-eef1a1 physical interaction relationship: participates_in CCO:I0019708 ! dnmt2-eef1a1 physical interaction relationship: participates_in CCO:I0019729 ! hbxip-eef1a1 physical interaction relationship: participates_in CCO:I0019751 ! itsn1-eef1a1 physical interaction relationship: participates_in CCO:I0019789 ! pole2-eef1a1 physical interaction relationship: participates_in CCO:I0019798 ! pqbp1-eef1a1 physical interaction relationship: participates_in CCO:I0019811 ! rfc5-eef1a1 physical interaction relationship: participates_in CCO:I0019842 ! ssr1-eef1a1 physical interaction relationship: participates_in CCO:I0019843 ! stmn2-eef1a1 physical interaction relationship: participates_in CCO:I0019852 ! tgif-eef1a1 physical interaction relationship: participates_in CCO:I0019863 ! tmsb4x-eef1a1 physical interaction relationship: participates_in CCO:I0019865 ! tnfrsf6-eef1a1 physical interaction relationship: participates_in CCO:I0019958 ! cradd-eef1a1 physical interaction relationship: participates_in CCO:I0020074 ! mllt3-eef1a1 physical interaction relationship: participates_in CCO:I0020111 ! plaur-eef1a1 physical interaction relationship: participates_in CCO:I0020426 ! rab27a-eef1a1 physical interaction relationship: transforms_into CCO:B0011634 ! EF1A1_HUMAN-Phosphotyrosine29 relationship: transforms_into CCO:B0011635 ! EF1A1_HUMAN-N6,N6,N6-trimethyllysine36 relationship: transforms_into CCO:B0011636 ! EF1A1_HUMAN-N6,N6-dimethyllysine55 relationship: transforms_into CCO:B0011637 ! EF1A1_HUMAN-N6,N6,N6-trimethyllysine79 relationship: transforms_into CCO:B0011638 ! EF1A1_HUMAN-Phosphotyrosine162 relationship: transforms_into CCO:B0011639 ! EF1A1_HUMAN-N6,N6-dimethyllysine165 relationship: transforms_into CCO:B0011640 ! EF1A1_HUMAN-N6,N6,N6-trimethyllysine318 relationship: transforms_into CCO:B0011641 ! EF1A1_HUMAN-N6-acetyllysine318 relationship: transforms_into CCO:B0064922 ! EF1A1_HUMAN-Phosphotyrosine86 relationship: transforms_into CCO:B0064923 ! EF1A1_HUMAN-Phosphotyrosine141 [Term] id: CCO:B0005832 name: EPHA2_HUMAN def: "Ephrin type-A receptor 2 precursor" [UniProtKB:P29317] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P29317] synonym: "Epithelial cell kinase" EXACT [UniProtKB:P29317] synonym: "Tyrosine-protein kinase receptor ECK" EXACT [UniProtKB:P29317] xref: EMBL:AAA53375.1 xref: UniProtKB:P29317 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004573 ! EPHA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0002759 ! ephrin receptor signaling pathway relationship: transforms_into CCO:B0011720 ! EPHA2_HUMAN-Phosphoserine570 relationship: transforms_into CCO:B0011721 ! EPHA2_HUMAN-Phosphotyrosine588 relationship: transforms_into CCO:B0011722 ! EPHA2_HUMAN-Phosphotyrosine594 relationship: transforms_into CCO:B0011723 ! EPHA2_HUMAN-Phosphotyrosine772 relationship: transforms_into CCO:B0011724 ! EPHA2_HUMAN-Phosphoserine897 relationship: transforms_into CCO:B0011725 ! EPHA2_HUMAN-Phosphothreonine898 relationship: transforms_into CCO:B0011726 ! EPHA2_HUMAN-Phosphoserine901 relationship: transforms_into CCO:B0011727 ! EPHA2_HUMAN-Phosphotyrosine921 relationship: transforms_into CCO:B0011728 ! EPHA2_HUMAN-Phosphotyrosine930 relationship: transforms_into CCO:B0065087 ! EPHA2_HUMAN-Phosphotyrosine575 relationship: transforms_into CCO:B0065088 ! EPHA2_HUMAN-Phosphoserine892 [Term] id: CCO:B0005833 name: EPHB4_HUMAN def: "Ephrin type-B receptor 4 precursor" [UniProtKB:P54760] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P54760] synonym: "Tyrosine-protein kinase receptor HTK" EXACT [UniProtKB:P54760] synonym: "Tyrosine-protein kinase TYRO11" EXACT [UniProtKB:P54760] xref: EMBL:AAA20598.1 xref: EMBL:AAH04264.1 xref: EMBL:AAK21010.1 xref: UniProtKB:P54760 xref: UniProtKB:Q9BTA5 xref: UniProtKB:Q9BXP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004575 ! EPHB4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011734 ! EPHB4_HUMAN-Phosphotyrosine590 relationship: transforms_into CCO:B0011735 ! EPHB4_HUMAN-Phosphotyrosine596 relationship: transforms_into CCO:B0011736 ! EPHB4_HUMAN-Phosphotyrosine774 relationship: transforms_into CCO:B0011737 ! EPHB4_HUMAN-Phosphotyrosine924 relationship: transforms_into CCO:B0065090 ! EPHB4_HUMAN-Phosphothreonine976 [Term] id: CCO:B0005834 name: EI2BG_HUMAN def: "Translation initiation factor eIF-2B subunit gamma" [UniProtKB:Q9NR50] synonym: "eIF-2B GDP-GTP exchange factor subunit gamma" EXACT [UniProtKB:Q9NR50] xref: EMBL:AAF91351.1 xref: EMBL:AAH18728.1 xref: EMBL:BAB14770.1 xref: EMBL:CAD38962.1 xref: EMBL:CAI23131.1 xref: EMBL:CAI23132.1 xref: UniProtKB:Q5QP89 xref: UniProtKB:Q5QP90 xref: UniProtKB:Q8NDB5 xref: UniProtKB:Q8WV57 xref: UniProtKB:Q9H850 xref: UniProtKB:Q9NR50 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004556 ! EIF2B3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0020300 ! eif2b3-stc2 physical interaction relationship: transforms_into CCO:B0041299 ! EI2BG_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0005835 name: DNJA1_HUMAN def: "DnaJ homolog subfamily A member 1" [UniProtKB:P31689] synonym: "DnaJ protein homolog 2" EXACT [UniProtKB:P31689] synonym: "HDJ-2" EXACT [UniProtKB:P31689] synonym: "Heat shock 40 kDa protein 4" EXACT [UniProtKB:P31689] synonym: "HSDJ" EXACT [UniProtKB:P31689] synonym: "HSJ-2" EXACT [UniProtKB:P31689] xref: EMBL:AAC37517.1 xref: EMBL:AAH08182.1 xref: EMBL:AAP35956.1 xref: EMBL:BAA02656.1 xref: UniProtKB:P31689 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004487 ! DNAJA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0008477 ! fzr1-dnaja1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016606 ! map3k1-dnaja1 physical interaction relationship: participates_in CCO:I0016689 ! map3k3-dnaja1 physical interaction relationship: participates_in CCO:I0016790 ! nfkb2-dnaja1 physical interaction relationship: participates_in CCO:I0016898 ! ripk1-dnaja1 physical interaction relationship: participates_in CCO:I0016927 ! map3k7ip1-dnaja1 physical interaction relationship: participates_in CCO:I0016942 ! q9nyj8-dnaja1 physical interaction relationship: participates_in CCO:I0016998 ! tnfrsf1a-dnaja1 physical interaction relationship: participates_in CCO:I0017065 ! tradd-dnaja1 physical interaction relationship: participates_in CCO:I0017094 ! traf1-dnaja1 physical interaction relationship: participates_in CCO:I0017120 ! traf2-dnaja1 physical interaction relationship: participates_in CCO:I0017139 ! traf6-dnaja1 physical interaction relationship: participates_in CCO:I0020192 ! th1l-dnaja1 physical interaction relationship: participates_in CCO:I0020229 ! arf4l-dnaja1 physical interaction relationship: transforms_into CCO:B0011547 ! DNJA1_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0011548 ! DNJA1_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0011549 ! DNJA1_HUMAN-Phosphotyrosine381 relationship: transforms_into CCO:B0064794 ! DNJA1_HUMAN-Phosphoserine340 [Term] id: CCO:B0005836 name: ACK1_HUMAN def: "Activated CDC42 kinase 1" [UniProtKB:Q07912] synonym: "ACK-1" EXACT [UniProtKB:Q07912] synonym: "EC 2.7.10.2" EXACT [UniProtKB:Q07912] synonym: "Tyrosine kinase non-receptor protein 2" EXACT [UniProtKB:Q07912] xref: EMBL:AAA53570.2 xref: EMBL:AAH08884.1 xref: EMBL:AAH28164.1 xref: EMBL:BAD18675.1 xref: UniProtKB:Q07912 xref: UniProtKB:Q6ZMQ0 xref: UniProtKB:Q8N6U7 xref: UniProtKB:Q96H59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004016 ! TNK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: transforms_into CCO:B0010427 ! ACK1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0010428 ! ACK1_HUMAN-Phosphotyrosine284 relationship: transforms_into CCO:B0010429 ! ACK1_HUMAN-Phosphotyrosine518 relationship: transforms_into CCO:B0010430 ! ACK1_HUMAN-Phosphotyrosine826 relationship: transforms_into CCO:B0010431 ! ACK1_HUMAN-Phosphotyrosine857 relationship: transforms_into CCO:B0010432 ! ACK1_HUMAN-Phosphotyrosine858 [Term] id: CCO:B0005837 name: PAXI_HUMAN def: "Paxillin" [UniProtKB:P49023] xref: EMBL:AAC05175.1 xref: EMBL:AAC50104.1 xref: EMBL:AAD00648.1 xref: EMBL:BAA18997.1 xref: EMBL:BAA18998.1 xref: UniProtKB:O14970 xref: UniProtKB:O14971 xref: UniProtKB:O60360 xref: UniProtKB:P49023 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005271 ! PXN_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003605 ! vinculin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0017927 ! pxn-rnf5-2 physical interaction relationship: participates_in CCO:I0017928 ! pxn-rnf5-3 physical interaction relationship: participates_in CCO:I0017929 ! rnf5-pxn-1 physical interaction relationship: participates_in CCO:I0018374 ! rnf5-pxn-2 physical interaction relationship: participates_in CCO:I0018375 ! rnf5-pxn-4 physical interaction relationship: participates_in CCO:I0019516 ! pxn-rnf5-4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: transforms_into CCO:B0013418 ! PAXI_HUMAN-Phosphotyrosine31 relationship: transforms_into CCO:B0013419 ! PAXI_HUMAN-Phosphotyrosine88 relationship: transforms_into CCO:B0013420 ! PAXI_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0013421 ! PAXI_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0013422 ! PAXI_HUMAN-Phosphotyrosine118 relationship: transforms_into CCO:B0013423 ! PAXI_HUMAN-Phosphotyrosine181 relationship: transforms_into CCO:B0013424 ! PAXI_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0069133 ! PAXI_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0069134 ! PAXI_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0069135 ! PAXI_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0069136 ! PAXI_HUMAN-Phosphoserine137 [Term] id: CCO:B0005838 name: H14_HUMAN def: "Histone H1.4" [UniProtKB:P10412] synonym: "Histone H1b" EXACT [UniProtKB:P10412] xref: EMBL:AAA63187.1 xref: EMBL:AAH96168.1 xref: EMBL:AAH96169.1 xref: EMBL:AAH99632.1 xref: EMBL:AAN06702.1 xref: EMBL:CAC04132.1 xref: UniProtKB:P10412 xref: UniProtKB:Q4VB25 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004742 ! HIST1H1E_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: transforms_into CCO:B0012001 ! H14_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0012002 ! H14_HUMAN-Phosphothreonine4 relationship: transforms_into CCO:B0012003 ! H14_HUMAN-Phosphothreonine18 relationship: transforms_into CCO:B0012004 ! H14_HUMAN-N6-methyllysine26 relationship: transforms_into CCO:B0012005 ! H14_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0012006 ! H14_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0012007 ! H14_HUMAN-Phosphoserine187 [Term] id: CCO:B0005839 name: CTND1_HUMAN def: "Catenin delta-1" [UniProtKB:O60716] synonym: "Cadherin-associated Src substrate" EXACT [UniProtKB:O60716] synonym: "CAS" EXACT [UniProtKB:O60716] synonym: "p120 catenin" EXACT [UniProtKB:O60716] synonym: "p120(cas)" EXACT [UniProtKB:O60716] synonym: "p120(ctn)" EXACT [UniProtKB:O60716] xref: EMBL:AAC39802.1 xref: EMBL:AAC39803.1 xref: EMBL:AAC39804.1 xref: EMBL:AAC39805.1 xref: EMBL:AAC39806.1 xref: EMBL:AAC39807.1 xref: EMBL:AAC39808.1 xref: EMBL:AAC39809.1 xref: EMBL:AAC39810.1 xref: EMBL:AAC39811.1 xref: EMBL:AAC39812.1 xref: EMBL:AAC39813.1 xref: EMBL:AAC39814.1 xref: EMBL:AAC39815.1 xref: EMBL:AAC39816.1 xref: EMBL:AAC39817.1 xref: EMBL:AAC39818.1 xref: EMBL:AAC39819.1 xref: EMBL:AAC39820.1 xref: EMBL:AAC39821.1 xref: EMBL:AAC39822.1 xref: EMBL:AAC39823.1 xref: EMBL:AAC39824.1 xref: EMBL:AAC39825.1 xref: EMBL:AAC39826.1 xref: EMBL:AAC39827.1 xref: EMBL:AAC39828.1 xref: EMBL:AAC39829.1 xref: EMBL:AAH75795.1 xref: EMBL:AAR84236.1 xref: EMBL:BAA20838.2 xref: EMBL:BAF85243.1 xref: UniProtKB:A8K939 xref: UniProtKB:O15088 xref: UniProtKB:O60713 xref: UniProtKB:O60714 xref: UniProtKB:O60715 xref: UniProtKB:O60716 xref: UniProtKB:O60935 xref: UniProtKB:Q6DHZ7 xref: UniProtKB:Q6RBX8 xref: UniProtKB:Q9UP71 xref: UniProtKB:Q9UP72 xref: UniProtKB:Q9UP73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004418 ! CTNND1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0011385 ! CTND1_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0011386 ! CTND1_HUMAN-Phosphotyrosine96 relationship: transforms_into CCO:B0011387 ! CTND1_HUMAN-Phosphotyrosine174 relationship: transforms_into CCO:B0011388 ! CTND1_HUMAN-Phosphotyrosine217 relationship: transforms_into CCO:B0011389 ! CTND1_HUMAN-Phosphotyrosine228 relationship: transforms_into CCO:B0011390 ! CTND1_HUMAN-Phosphotyrosine257 relationship: transforms_into CCO:B0011391 ! CTND1_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0011392 ! CTND1_HUMAN-Phosphoserine269 relationship: transforms_into CCO:B0011393 ! CTND1_HUMAN-Phosphotyrosine280 relationship: transforms_into CCO:B0011394 ! CTND1_HUMAN-Phosphoserine288 relationship: transforms_into CCO:B0011395 ! CTND1_HUMAN-Phosphotyrosine291 relationship: transforms_into CCO:B0011396 ! CTND1_HUMAN-Phosphotyrosine302 relationship: transforms_into CCO:B0011397 ! CTND1_HUMAN-Phosphothreonine310 relationship: transforms_into CCO:B0011398 ! CTND1_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0011399 ! CTND1_HUMAN-Phosphotyrosine321 relationship: transforms_into CCO:B0011400 ! CTND1_HUMAN-Phosphotyrosine334 relationship: transforms_into CCO:B0011401 ! CTND1_HUMAN-Phosphoserine349 relationship: transforms_into CCO:B0011402 ! CTND1_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0011403 ! CTND1_HUMAN-Phosphoserine859 relationship: transforms_into CCO:B0011404 ! CTND1_HUMAN-Phosphotyrosine865 relationship: transforms_into CCO:B0011405 ! CTND1_HUMAN-Phosphothreonine916 relationship: transforms_into CCO:B0031307 ! CTND1_HUMAN-Phosphotyrosine904 relationship: transforms_into CCO:B0048211 ! CTND1_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0048212 ! CTND1_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0048213 ! CTND1_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0048214 ! CTND1_HUMAN-Phosphothreonine869 [Term] id: CCO:B0005840 name: AT2A2_HUMAN def: "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2" [UniProtKB:P16615] synonym: "Calcium pump 2" EXACT [UniProtKB:P16615] synonym: "Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform" EXACT [UniProtKB:P16615] synonym: "EC 3.6.3.8" EXACT [UniProtKB:P16615] synonym: "Endoplasmic reticulum class 1/2 Ca(2+) ATPase" EXACT [UniProtKB:P16615] synonym: "SERCA2" EXACT [UniProtKB:P16615] synonym: "SR Ca(2+)-ATPase 2" EXACT [UniProtKB:P16615] xref: EMBL:AAA52757.1 xref: EMBL:AAA52758.1 xref: EMBL:AAA53193.1 xref: EMBL:AAA53194.1 xref: EMBL:AAH35588.1 xref: UniProtKB:P16614 xref: UniProtKB:P16615 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004113 ! ATP2A2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0017033 ! tnfrsf1a-atp2a2 physical interaction relationship: participates_in CCO:I0017053 ! tnfrsf1b-atp2a2 physical interaction relationship: participates_in CCO:I0017084 ! tradd-atp2a2 physical interaction relationship: participates_in CCO:I0017153 ! traf6-atp2a2 physical interaction relationship: participates_in CCO:P0000685 ! ER-nuclear signaling pathway relationship: transforms_into CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: transforms_into CCO:B0010642 ! AT2A2_HUMAN-Phosphoserine663 relationship: transforms_into CCO:B0063647 ! AT2A2_HUMAN-Nitrated tyrosine294 relationship: transforms_into CCO:B0063648 ! AT2A2_HUMAN-Nitrated tyrosine295 [Term] id: CCO:B0005841 name: BCAR1_HUMAN def: "Breast cancer anti-estrogen resistance protein 1" [UniProtKB:P56945] synonym: "Cas scaffolding protein family member 1" EXACT [UniProtKB:P56945] synonym: "CRK-associated substrate" EXACT [UniProtKB:P56945] synonym: "p130cas" EXACT [UniProtKB:P56945] xref: EMBL:AAF27527.1 xref: EMBL:BAA92711.1 xref: EMBL:BAB55230.1 xref: EMBL:CAB75875.2 xref: UniProtKB:P56945 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004146 ! BCAR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:I0008200 ! bcar1-ppp1r15a physical interaction relationship: participates_in CCO:I0008361 ! bcar1-e2f2 physical interaction relationship: participates_in CCO:I0019666 ! bcar1-hspa5 physical interaction relationship: participates_in CCO:I0019923 ! bcar1-fxyd6 physical interaction relationship: participates_in CCO:I0019924 ! bcar1-tuba1 physical interaction relationship: participates_in CCO:I0019925 ! bcar1-vps11 physical interaction relationship: participates_in CCO:I0020256 ! bcar1-efs physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0002757 ! nerve growth factor receptor signaling pathway relationship: participates_in CCO:P0002969 ! antigen receptor-mediated signaling pathway relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0010753 ! BCAR1_HUMAN-Phosphotyrosine128 relationship: transforms_into CCO:B0010754 ! BCAR1_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0010755 ! BCAR1_HUMAN-Phosphotyrosine222 relationship: transforms_into CCO:B0010756 ! BCAR1_HUMAN-Phosphotyrosine224 relationship: transforms_into CCO:B0010757 ! BCAR1_HUMAN-Phosphotyrosine234 relationship: transforms_into CCO:B0010758 ! BCAR1_HUMAN-Phosphotyrosine249 relationship: transforms_into CCO:B0010759 ! BCAR1_HUMAN-Phosphotyrosine327 relationship: transforms_into CCO:B0010760 ! BCAR1_HUMAN-Phosphotyrosine362 relationship: transforms_into CCO:B0010761 ! BCAR1_HUMAN-Phosphotyrosine387 relationship: transforms_into CCO:B0010762 ! BCAR1_HUMAN-Phosphotyrosine410 relationship: transforms_into CCO:B0010763 ! BCAR1_HUMAN-Phosphoserine639 relationship: transforms_into CCO:B0063785 ! BCAR1_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0063786 ! BCAR1_HUMAN-Phosphothreonine269 relationship: transforms_into CCO:B0063787 ! BCAR1_HUMAN-Phosphoserine292 [Term] id: CCO:B0005842 name: HSPB1_HUMAN def: "Heat shock protein beta-1" [UniProtKB:P04792] synonym: "28 kDa heat shock protein" EXACT [UniProtKB:P04792] synonym: "Estrogen-regulated 24 kDa protein" EXACT [UniProtKB:P04792] synonym: "Heat shock 27 kDa protein" EXACT [UniProtKB:P04792] synonym: "HSP 27" EXACT [UniProtKB:P04792] synonym: "HspB1" EXACT [UniProtKB:P04792] synonym: "SRP27" EXACT [UniProtKB:P04792] synonym: "Stress-responsive protein 27" EXACT [UniProtKB:P04792] xref: EMBL:AAA62175.1 xref: EMBL:AAB20722.1 xref: EMBL:AAB51056.1 xref: EMBL:AAH00510.1 xref: EMBL:AAH12292.1 xref: EMBL:AAH12768.1 xref: EMBL:AAH14920.1 xref: EMBL:AAH73768.1 xref: EMBL:AAV38691.1 xref: EMBL:ABC88475.1 xref: EMBL:BAB17232.1 xref: EMBL:CAA34498.1 xref: EMBL:CAA38016.1 xref: EMBL:CAA80636.1 xref: EMBL:CAG28542.1 xref: EMBL:CAG38728.1 xref: UniProtKB:P04792 xref: UniProtKB:Q6FI47 xref: UniProtKB:Q96C20 xref: UniProtKB:Q96EI7 xref: UniProtKB:Q9UC31 xref: UniProtKB:Q9UC34 xref: UniProtKB:Q9UC35 xref: UniProtKB:Q9UC36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004839 ! HSPB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008123 ! hspb1-rif1 physical interaction relationship: participates_in CCO:I0008124 ! hspb1-tp53 physical interaction relationship: participates_in CCO:I0018076 ! hspb7-hspb1-1 physical interaction relationship: participates_in CCO:I0018077 ! hspb7-hspb1-2 physical interaction relationship: participates_in CCO:I0019739 ! hspb1-med31 physical interaction relationship: participates_in CCO:I0019740 ! hspb1-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020031 ! hspb1-igsf21 physical interaction relationship: participates_in CCO:I0020032 ! hspb1-pp physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0012279 ! HSPB1_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0012280 ! HSPB1_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0012281 ! HSPB1_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0012282 ! HSPB1_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0012283 ! HSPB1_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0012284 ! HSPB1_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0012285 ! HSPB1_HUMAN-N6-acetyllysine123 [Term] id: CCO:B0005843 name: GRP78_HUMAN def: "78 kDa glucose-regulated protein precursor" [UniProtKB:P11021] synonym: "BiP" EXACT [UniProtKB:P11021] synonym: "Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78" EXACT [UniProtKB:P11021] synonym: "GRP 78" EXACT [UniProtKB:P11021] synonym: "Heat shock 70 kDa protein 5" EXACT [UniProtKB:P11021] synonym: "Immunoglobulin heavy chain-binding protein" EXACT [UniProtKB:P11021] xref: EMBL:AAA52614.1 xref: EMBL:AAF13605.1 xref: EMBL:AAF42836.1 xref: EMBL:AAH20235.1 xref: EMBL:ABD04090.1 xref: EMBL:CAA42595.1 xref: EMBL:CAA61201.1 xref: EMBL:CAB71335.1 xref: UniProtKB:P11021 xref: UniProtKB:Q2EF78 xref: UniProtKB:Q9NPF1 xref: UniProtKB:Q9UK02 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004732 ! HSPA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0008801 ! psme3-hspa5 physical interaction relationship: participates_in CCO:I0016349 ! rel-hspa5 physical interaction relationship: participates_in CCO:I0016370 ! nfkbia-hspa5 physical interaction relationship: participates_in CCO:I0016389 ! nfkbib-hspa5 physical interaction relationship: participates_in CCO:I0016449 ! ikbkb-hspa5 physical interaction relationship: participates_in CCO:I0016491 ! ikbkg-hspa5 physical interaction relationship: participates_in CCO:I0016571 ! tank-hspa5 physical interaction relationship: participates_in CCO:I0016594 ! map3k1-hspa5 physical interaction relationship: participates_in CCO:I0016668 ! map3k3-hspa5 physical interaction relationship: participates_in CCO:I0016776 ! nfkb2-hspa5-1 physical interaction relationship: participates_in CCO:I0016854 ! relb-hspa5 physical interaction relationship: participates_in CCO:I0016893 ! ripk1-hspa5 physical interaction relationship: participates_in CCO:I0016923 ! map3k7ip1-hspa5 physical interaction relationship: participates_in CCO:I0016937 ! q9nyj8-hspa5 physical interaction relationship: participates_in CCO:I0016959 ! tbk1-hspa5 physical interaction relationship: participates_in CCO:I0016986 ! tnfrsf1a-hspa5 physical interaction relationship: participates_in CCO:I0017114 ! traf2-hspa5 physical interaction relationship: participates_in CCO:I0017135 ! traf6-hspa5 physical interaction relationship: participates_in CCO:I0019666 ! bcar1-hspa5 physical interaction relationship: participates_in CCO:I0020545 ! dpysl5-hspa5 physical interaction relationship: transforms_into CCO:B0011985 ! GRP78_HUMAN-Phosphothreonine166 relationship: transforms_into CCO:B0011986 ! GRP78_HUMAN-Phosphotyrosine466 relationship: transforms_into CCO:B0011987 ! GRP78_HUMAN-Phosphoserine571 [Term] id: CCO:B0005844 name: K1C17_HUMAN def: "Keratin, type I cytoskeletal 17" [UniProtKB:Q04695] synonym: "39.1" EXACT [UniProtKB:Q04695] synonym: "CK-17" EXACT [UniProtKB:Q04695] synonym: "Cytokeratin-17" EXACT [UniProtKB:Q04695] synonym: "K17" EXACT [UniProtKB:Q04695] synonym: "Keratin-17" EXACT [UniProtKB:Q04695] xref: EMBL:AAB34565.1 xref: EMBL:AAH00159.2 xref: EMBL:AAH11901.1 xref: EMBL:AAH56421.1 xref: EMBL:AAH72018.1 xref: EMBL:AAH72019.1 xref: EMBL:ABQ96595.1 xref: EMBL:ABQ96596.1 xref: EMBL:ABQ96597.1 xref: EMBL:ABQ96598.1 xref: EMBL:BAC04534.1 xref: EMBL:CAA44451.1 xref: EMBL:CAA79626.1 xref: UniProtKB:A5Z1M9 xref: UniProtKB:A5Z1N0 xref: UniProtKB:A5Z1N1 xref: UniProtKB:A5Z1N2 xref: UniProtKB:A6NDV6 xref: UniProtKB:A6NKQ2 xref: UniProtKB:Q04695 xref: UniProtKB:Q6IP98 xref: UniProtKB:Q8N1P6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004922 ! KRT17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015426 ! krt17-krt6a physical interaction relationship: transforms_into CCO:B0012458 ! K1C17_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0012459 ! K1C17_HUMAN-Phosphoserine319 [Term] id: CCO:B0005845 name: LRC59_HUMAN def: "Leucine-rich repeat-containing protein 59" [UniProtKB:Q96AG4] xref: EMBL:AAF69611.1 xref: EMBL:AAH17168.1 xref: EMBL:AAH52279.1 xref: UniProtKB:Q96AG4 xref: UniProtKB:Q9P189 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004988 ! LRRC59_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0017021 ! tnfrsf1a-q96ag4 physical interaction relationship: transforms_into CCO:B0067772 ! LRC59_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0067773 ! LRC59_HUMAN-Phosphoserine25 [Term] id: CCO:B0005846 name: FAK2_HUMAN def: "Protein tyrosine kinase 2 beta" [UniProtKB:Q14289] synonym: "CADTK" EXACT [UniProtKB:Q14289] synonym: "CAK beta" EXACT [UniProtKB:Q14289] synonym: "Calcium-dependent tyrosine kinase" EXACT [UniProtKB:Q14289] synonym: "Cell adhesion kinase beta" EXACT [UniProtKB:Q14289] synonym: "EC 2.7.10.2" EXACT [UniProtKB:Q14289] synonym: "FADK 2" EXACT [UniProtKB:Q14289] synonym: "Focal adhesion kinase 2" EXACT [UniProtKB:Q14289] synonym: "Proline-rich tyrosine kinase 2" EXACT [UniProtKB:Q14289] synonym: "RAFTK" EXACT [UniProtKB:Q14289] synonym: "Related adhesion focal tyrosine kinase" EXACT [UniProtKB:Q14289] xref: EMBL:AAB35701.1 xref: EMBL:AAB47217.1 xref: EMBL:AAC05330.1 xref: EMBL:AAC50203.1 xref: EMBL:AAH42599.1 xref: EMBL:BAA08289.1 xref: UniProtKB:Q13475 xref: UniProtKB:Q14289 xref: UniProtKB:Q14290 xref: UniProtKB:Q16709 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004607 ! PTK2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007963 ! egfr-yes-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0011835 ! FAK2_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0011836 ! FAK2_HUMAN-Phosphotyrosine402 relationship: transforms_into CCO:B0011837 ! FAK2_HUMAN-Phosphotyrosine579 relationship: transforms_into CCO:B0011838 ! FAK2_HUMAN-Phosphotyrosine580 relationship: transforms_into CCO:B0011839 ! FAK2_HUMAN-Phosphotyrosine881 relationship: transforms_into CCO:B0031316 ! FAK2_HUMAN-Phosphotyrosine440 [Term] id: CCO:B0005847 name: MPCP_HUMAN def: "Phosphate carrier protein, mitochondrial precursor" [UniProtKB:Q00325] synonym: "Phosphate transport protein" EXACT [UniProtKB:Q00325] synonym: "PTP" EXACT [UniProtKB:Q00325] synonym: "Solute carrier family 25 member 3" EXACT [UniProtKB:Q00325] xref: EMBL:AAH00998.1 xref: EMBL:AAH01328.1 xref: EMBL:AAH03504.1 xref: EMBL:AAH04345.1 xref: EMBL:AAH06455.1 xref: EMBL:AAH11574.1 xref: EMBL:AAH11641.1 xref: EMBL:AAH14019.1 xref: EMBL:AAH15379.2 xref: EMBL:BAB93517.1 xref: EMBL:CAA42641.1 xref: EMBL:CAB56611.1 xref: EMBL:CAB56612.1 xref: UniProtKB:Q00325 xref: UniProtKB:Q96A03 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005115 ! SLC25A3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007126 ! egfr-yes-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017008 ! tnfrsf1a-slc25a3 physical interaction relationship: participates_in CCO:I0017071 ! tradd-slc25a3 physical interaction relationship: transforms_into CCO:B0012980 ! MPCP_HUMAN-N6-acetyllysine99 relationship: transforms_into CCO:B0012981 ! MPCP_HUMAN-N6-acetyllysine209 [Term] id: CCO:B0005848 name: BBC3_HUMAN def: "Bcl-2-binding component 3" [UniProtKB:Q9BXH1] synonym: "JFY-1" EXACT [UniProtKB:Q9BXH1] synonym: "p53 up-regulated modulator of apoptosis" EXACT [UniProtKB:Q9BXH1] xref: EMBL:AAB51243.2 xref: EMBL:AAK31316.1 xref: EMBL:AAK39542.1 xref: EMBL:AAK39543.1 xref: UniProtKB:O00171 xref: UniProtKB:Q96PG9 xref: UniProtKB:Q9BXH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004144 ! BBC3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: participates_in CCO:I0007129 ! bbc3-bcl2-5 direct interaction relationship: participates_in CCO:I0007130 ! bbc3-bcl2-6 direct interaction relationship: participates_in CCO:I0007766 ! bbc3-bcl2-4 direct interaction relationship: participates_in CCO:I0007883 ! puma_bcl2_human direct interaction relationship: participates_in CCO:I0007936 ! bcl2-bbc3 direct interaction relationship: participates_in CCO:I0019271 ! bbc3-bclw-1 direct interaction relationship: participates_in CCO:I0019467 ! bcl2l1-bbc3 direct interaction relationship: participates_in CCO:I0019470 ! bcl2l2-bbc3 direct interaction relationship: participates_in CCO:I0019473 ! mcl1-bbc3 direct interaction relationship: participates_in CCO:I0019475 ! bcl2a1-bbc3 direct interaction relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0005849 name: KI13B_HUMAN def: "Kinesin-like protein KIF13B" [UniProtKB:Q9NQT8] synonym: "Kinesin-like protein GAKIN" EXACT [UniProtKB:Q9NQT8] xref: EMBL:AAF81263.1 xref: EMBL:BAA31614.3 xref: EMBL:CAC29496.1 xref: UniProtKB:O75134 xref: UniProtKB:Q9BYJ6 xref: UniProtKB:Q9NQT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004939 ! KIF13B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007135 ! dlg1-kif13b-3 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012529 ! KI13B_HUMAN-Phosphoserine1410 relationship: transforms_into CCO:B0041155 ! KI13B_HUMAN-Phosphoserine1644 relationship: transforms_into CCO:B0067300 ! KI13B_HUMAN-Phosphoserine1379 relationship: transforms_into CCO:B0067301 ! KI13B_HUMAN-Phosphoserine1382 relationship: transforms_into CCO:B0067302 ! KI13B_HUMAN-Phosphoserine1432 relationship: transforms_into CCO:B0067303 ! KI13B_HUMAN-Phosphoserine1438 [Term] id: CCO:B0005850 name: GLI3_HUMAN def: "Zinc finger protein GLI3" [UniProtKB:P10071] xref: EMBL:AAA52564.1 xref: EMBL:AAI13617.1 xref: EMBL:AAI17169.1 xref: EMBL:AAP21869.1 xref: EMBL:AAS01998.1 xref: EMBL:AAS02015.1 xref: EMBL:CAB59315.1 xref: EMBL:EAL24002.1 xref: UniProtKB:A4D1W1 xref: UniProtKB:O75219 xref: UniProtKB:P10071 xref: UniProtKB:Q17RW4 xref: UniProtKB:Q75MT0 xref: UniProtKB:Q75MU9 xref: UniProtKB:Q9UDT5 xref: UniProtKB:Q9UJ39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004702 ! GLI3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: participates_in CCO:I0007136 ! gli3-sufu-1 direct interaction relationship: participates_in CCO:I0015965 ! stk36-gli3-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001156 ! smoothened signaling pathway involved in ventral spinal cord interneuron specification relationship: participates_in CCO:P0001157 ! smoothened signaling pathway involved in spinal cord motor neuron cell fate specification relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: transforms_into CCO:B0011941 ! GLI3_HUMAN-Phosphoserine19 [Term] id: CCO:B0005851 name: DIRA2_HUMAN def: "GTP-binding protein Di-Ras2" [UniProtKB:Q96HU8] synonym: "Distinct subgroup of the Ras family member 2" EXACT [UniProtKB:Q96HU8] xref: EMBL:AAH08065.1 xref: EMBL:BAC01116.1 xref: EMBL:CAI15748.1 xref: UniProtKB:Q96HU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004472 ! DIRAS2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007138 ! calm physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0005852 name: ERBB3_HUMAN def: "Receptor tyrosine-protein kinase erbB-3 precursor" [UniProtKB:P21860] synonym: "c-erbB3" EXACT [UniProtKB:P21860] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P21860] synonym: "Tyrosine kinase-type cell surface receptor HER3" EXACT [UniProtKB:P21860] xref: EMBL:AAA35790.1 xref: EMBL:AAA35979.1 xref: EMBL:AAB26935.1 xref: EMBL:AAH82992.1 xref: UniProtKB:P21860 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004578 ! ERBB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006444 ! erbb2-egfr physical interaction relationship: participates_in CCO:I0007143 ! erbb3-pa2g4-1 physical interaction relationship: participates_in CCO:I0007365 ! erbb1-erbb3-2 physical interaction relationship: participates_in CCO:I0007592 ! erbb1-erbb3-1 physical interaction relationship: participates_in CCO:I0016315 ! erbb3-erbb2-3 physical interaction relationship: participates_in CCO:I0016316 ! erbb3-erbb4-2 physical interaction relationship: participates_in CCO:I0016317 ! p85a-erbb3-1 physical interaction relationship: participates_in CCO:I0018529 ! erbb3-erbb2-2 physical interaction relationship: participates_in CCO:I0018530 ! p85a-erbb3-3 physical interaction relationship: participates_in CCO:I0018865 ! erbb3-erbb2-1 physical interaction relationship: participates_in CCO:I0018866 ! erbb3-erbb4-1 physical interaction relationship: participates_in CCO:I0018868 ! p85a-erbb3-2 physical interaction relationship: participates_in CCO:I0020354 ! kiaa1229-erbb3 physical interaction relationship: participates_in CCO:I0020649 ! rasa4-erbb3 physical interaction relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0001084 ! phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001087 ! positive regulation of phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: transforms_into CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 [Term] id: CCO:B0005853 name: RL28_HUMAN def: "60S ribosomal protein L28" [UniProtKB:P46779] xref: EMBL:AAA85657.1 xref: EMBL:AAH10173.1 xref: EMBL:AAH10182.1 xref: EMBL:AAH11582.1 xref: EMBL:CAG33305.1 xref: UniProtKB:P46779 xref: UniProtKB:Q6IAY0 xref: UniProtKB:Q96FX1 xref: UniProtKB:Q9BWQ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005505 ! RPL28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: transforms_into CCO:B0013889 ! RL28_HUMAN-N-acetylserine2 [Term] id: CCO:B0005854 name: PABP1_HUMAN def: "Polyadenylate-binding protein 1" [UniProtKB:P11940] synonym: "PABP 1" EXACT [UniProtKB:P11940] synonym: "Poly(A)-binding protein 1" EXACT [UniProtKB:P11940] xref: EMBL:AAD08718.1 xref: EMBL:AAH15958.1 xref: EMBL:AAH23520.1 xref: EMBL:AAH41863.1 xref: EMBL:CAA68428.1 xref: EMBL:CAA88401.1 xref: UniProtKB:P11940 xref: UniProtKB:Q15097 xref: UniProtKB:Q93004 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005253 ! PABPC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016794 ! nfkb2-pabpc1 physical interaction relationship: participates_in CCO:I0016843 ! map3k14-pabpc1 physical interaction relationship: participates_in CCO:I0017277 ! eif4g-pabp1 physical interaction relationship: participates_in CCO:I0018199 ! atx2-pabp physical interaction relationship: participates_in CCO:I0018357 ! pabp-paip1 2 physical interaction relationship: participates_in CCO:I0018358 ! paip1-pabp 2 physical interaction relationship: participates_in CCO:I0018667 ! atx2-pabp-1 physical interaction relationship: participates_in CCO:I0018861 ! pabp-paip1 3 direct interaction relationship: participates_in CCO:I0018862 ! paip1-pabp 3 direct interaction relationship: participates_in CCO:I0019264 ! atx2-pabp-2 physical interaction relationship: participates_in CCO:I0019286 ! pabp-paip1 physical interaction relationship: participates_in CCO:I0019287 ! paip1-pabp physical interaction relationship: participates_in CCO:P0002800 ! mRNA stabilization relationship: transforms_into CCO:B0013369 ! PABP1_HUMAN-Phosphotyrosine364 relationship: transforms_into CCO:B0013370 ! PABP1_HUMAN-arginine455 relationship: transforms_into CCO:B0013371 ! PABP1_HUMAN-arginine460 relationship: transforms_into CCO:B0013372 ! PABP1_HUMAN-Omega-N-methylated arginine493 relationship: transforms_into CCO:B0031362 ! PABP1_HUMAN-Phosphotyrosine116 [Term] id: CCO:B0005855 name: RL12_HUMAN def: "60S ribosomal protein L12" [UniProtKB:P30050] xref: EMBL:AAA36157.1 xref: EMBL:AAH50644.1 xref: EMBL:AAH59950.1 xref: EMBL:AAH94831.1 xref: EMBL:AAI05604.1 xref: EMBL:CAH72929.1 xref: EMBL:EAW87669.1 xref: UniProtKB:P30050 xref: UniProtKB:Q5VVV2 xref: UniProtKB:Q6PB27 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005497 ! RPL12_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0013881 ! RL12_HUMAN-Phosphotyrosine14 relationship: transforms_into CCO:B0013882 ! RL12_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0013883 ! RL12_HUMAN-Phosphoserine165 [Term] id: CCO:B0005856 name: RL24_HUMAN def: "60S ribosomal protein L24" [UniProtKB:P83731] synonym: "Ribosomal protein L30" EXACT [UniProtKB:P83731] xref: EMBL:AAC28251.1 xref: EMBL:AAH00690.1 xref: EMBL:AAH70193.1 xref: EMBL:BAA25836.1 xref: EMBL:BAB79466.1 xref: EMBL:CAG33010.1 xref: UniProtKB:P38663 xref: UniProtKB:P83731 xref: UniProtKB:Q6IBS3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005503 ! RPL24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016651 ! map3k1-rpl24 physical interaction relationship: transforms_into CCO:B0013887 ! RL24_HUMAN-Phosphothreonine83 relationship: transforms_into CCO:B0013888 ! RL24_HUMAN-Phosphoserine86 [Term] id: CCO:B0005857 name: RL15_HUMAN def: "60S ribosomal protein L15" [UniProtKB:P61313] xref: EMBL:AAA36583.1 xref: EMBL:AAG15591.1 xref: EMBL:AAG44837.1 xref: EMBL:AAH14837.1 xref: EMBL:AAH68198.1 xref: EMBL:AAH70328.1 xref: EMBL:AAH71672.1 xref: EMBL:AAQ24859.1 xref: EMBL:BAB79461.1 xref: UniProtKB:P39030 xref: UniProtKB:P41051 xref: UniProtKB:P61313 xref: UniProtKB:Q6IPX6 xref: UniProtKB:Q8WYP2 xref: UniProtKB:Q96C44 xref: UniProtKB:Q9H2E5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005498 ! RPL15_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: transforms_into CCO:B0070064 ! RL15_HUMAN-Phosphoserine97 [Term] id: CCO:B0005858 name: RL11_HUMAN def: "60S ribosomal protein L11" [UniProtKB:P62913] synonym: "CLL-associated antigen KW-12" EXACT [UniProtKB:P62913] xref: EMBL:AAC15856.1 xref: EMBL:AAD20460.3 xref: EMBL:AAH18970.1 xref: EMBL:AAL99919.1 xref: EMBL:BAA25831.1 xref: EMBL:CAA55816.1 xref: UniProtKB:P25121 xref: UniProtKB:P39026 xref: UniProtKB:P62913 xref: UniProtKB:Q8TDH2 xref: UniProtKB:Q9Y674 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005496 ! RPL11_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: transforms_into CCO:B0013880 ! RL11_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005859 name: RL27_HUMAN def: "60S ribosomal protein L27" [UniProtKB:P61353] xref: EMBL:AAA19815.1 xref: EMBL:AAC15857.1 xref: EMBL:AAH01700.1 xref: EMBL:AAH02588.1 xref: EMBL:AAH07273.1 xref: EMBL:AAH10026.1 xref: EMBL:AAH98560.1 xref: EMBL:BAB79492.1 xref: UniProtKB:P08526 xref: UniProtKB:P61353 xref: UniProtKB:Q4G0A9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005504 ! RPL27_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0005860 name: RL8_HUMAN def: "60S ribosomal protein L8" [UniProtKB:P62917] xref: EMBL:AAH00047.2 xref: EMBL:AAH00077.1 xref: EMBL:AAH12197.1 xref: EMBL:AAH13104.1 xref: EMBL:AAH93064.1 xref: EMBL:AAP36043.1 xref: EMBL:BAA25829.1 xref: EMBL:BAB79459.1 xref: EMBL:CAA82248.1 xref: EMBL:CAG33327.1 xref: UniProtKB:P25120 xref: UniProtKB:P62917 xref: UniProtKB:Q567Q7 xref: UniProtKB:Q969V7 xref: UniProtKB:Q9BWQ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005510 ! RPL8_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0008171 ! supt5h-rpl8 physical interaction relationship: participates_in CCO:I0019717 ! fgfr3-rpl8 physical interaction relationship: transforms_into CCO:B0013895 ! RL8_HUMAN-Phosphotyrosine133 [Term] id: CCO:B0005861 name: RL4_HUMAN def: "60S ribosomal protein L4" [UniProtKB:P36578] synonym: "L1" EXACT [UniProtKB:P36578] xref: EMBL:AAA60281.2 xref: EMBL:AAH01365.1 xref: EMBL:AAH05817.1 xref: EMBL:AAH07748.1 xref: EMBL:AAH07996.1 xref: EMBL:AAH09888.1 xref: EMBL:AAH10151.1 xref: EMBL:AAH14653.1 xref: EMBL:AAH66925.1 xref: EMBL:AAH95427.1 xref: EMBL:BAA04887.1 xref: EMBL:BAB79458.1 xref: UniProtKB:P36578 xref: UniProtKB:P39029 xref: UniProtKB:Q4VBR0 xref: UniProtKB:Q969Z9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005507 ! RPL4_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017229 ! map3k1-rpl4 physical interaction relationship: participates_in CCO:I0018444 ! pbx2-rpl4 physical interaction relationship: transforms_into CCO:B0013890 ! RL4_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013891 ! RL4_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0070088 ! RL4_HUMAN-Phosphoserine365 [Term] id: CCO:B0005862 name: RL21_HUMAN def: "60S ribosomal protein L21" [UniProtKB:P46778] xref: EMBL:AAA80462.1 xref: EMBL:AAA85655.1 xref: EMBL:AAA93231.1 xref: EMBL:AAH01603.1 xref: EMBL:AAH07505.1 xref: EMBL:AAH62981.1 xref: EMBL:AAH70184.1 xref: EMBL:AAH70323.1 xref: EMBL:AAH70330.1 xref: EMBL:BAA25835.1 xref: EMBL:BAB79464.1 xref: EMBL:CAA61582.1 xref: UniProtKB:P46778 xref: UniProtKB:Q16699 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005501 ! RPL21_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008501 ! rpl21-pim2 physical interaction relationship: transforms_into CCO:B0036028 ! RL21_HUMAN-Phosphothreonine47 [Term] id: CCO:B0005863 name: H11_HUMAN def: "Histone H1.1" [UniProtKB:Q02539] xref: EMBL:AAH69492.1 xref: EMBL:AAI01594.1 xref: EMBL:AAI12141.1 xref: EMBL:AAN06699.1 xref: EMBL:CAA40409.1 xref: UniProtKB:Q02539 xref: UniProtKB:Q3MJ34 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004741 ! HIST1H1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: transforms_into CCO:B0011999 ! H11_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0012000 ! H11_HUMAN-Phosphothreonine162 [Term] id: CCO:B0005864 name: RLA2_HUMAN def: "60S acidic ribosomal protein P2" [UniProtKB:P05387] synonym: "Renal carcinoma antigen NY-REN-44" EXACT [UniProtKB:P05387] xref: EMBL:AAA36472.1 xref: EMBL:AAH05354.1 xref: EMBL:AAH05920.1 xref: EMBL:AAH07573.1 xref: EMBL:AAH62314.1 xref: EMBL:BAB79475.1 xref: UniProtKB:P05387 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005513 ! RPLP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007145 ! pa2g4-ncl-top1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016502 ! ikbkg-rplp2 physical interaction relationship: participates_in CCO:I0016600 ! map3k1-rplp2 physical interaction relationship: participates_in CCO:I0016785 ! nfkb2-rplp2 physical interaction relationship: participates_in CCO:I0016861 ! relb-rplp2 physical interaction relationship: transforms_into CCO:B0013904 ! RLA2_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0013905 ! RLA2_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0013906 ! RLA2_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0036029 ! RLA2_HUMAN-Phosphoserine16 [Term] id: CCO:B0005865 name: TF65_HUMAN def: "Transcription factor p65" [UniProtKB:Q04206] synonym: "Nuclear factor NF-kappa-B p65 subunit" EXACT [UniProtKB:Q04206] xref: EMBL:AAA20946.1 xref: EMBL:AAA36408.1 xref: EMBL:AAH33522.1 xref: EMBL:AAR13863.1 xref: EMBL:CAA80524.2 xref: UniProtKB:Q04206 xref: UniProtKB:Q6GTV1 xref: UniProtKB:Q6SLK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005765 ! RELA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007150 ! cbp-atf3 physical interaction relationship: participates_in CCO:I0015962 ! rps6ka5-rela physical interaction relationship: participates_in CCO:I0016015 ! rela-pdcd11-1 physical interaction relationship: participates_in CCO:I0016143 ! hdac1-rela direct interaction relationship: participates_in CCO:I0016145 ! hdac1-rela-4 direct interaction relationship: participates_in CCO:I0016245 ! rela-dhx9-2 physical interaction relationship: participates_in CCO:I0017675 ! dhx9-rela-1 physical interaction relationship: participates_in CCO:I0017787 ! nfkb1-nfkbia-1 physical interaction relationship: participates_in CCO:I0017972 ! rela-aatf-2 physical interaction relationship: participates_in CCO:I0018126 ! rela-aatf physical interaction relationship: participates_in CCO:I0018127 ! rela-aatf-1 physical interaction relationship: participates_in CCO:I0018302 ! dhx9-rela-2 physical interaction relationship: participates_in CCO:I0018510 ! rela-rela-3 physical interaction relationship: participates_in CCO:I0018511 ! rela-chuk-1 physical interaction relationship: participates_in CCO:I0018555 ! rela-atf3 direct interaction relationship: participates_in CCO:I0018556 ! rela-atf3-1 direct interaction relationship: participates_in CCO:I0018557 ! rela-cbp direct interaction relationship: participates_in CCO:I0018558 ! rela-cbp-1 physical interaction relationship: participates_in CCO:I0018871 ! hdac1-rela-2 physical interaction relationship: participates_in CCO:I0018872 ! hdac1-rela-3 physical interaction relationship: participates_in CCO:I0019242 ! rela-dhx9-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0014345 ! TF65_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0041207 ! TF65_HUMAN-N6-acetyllysine122 relationship: transforms_into CCO:B0041208 ! TF65_HUMAN-N6-acetyllysine123 relationship: transforms_into CCO:B0041209 ! TF65_HUMAN-Phosphothreonine254 relationship: transforms_into CCO:B0041210 ! TF65_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0041211 ! TF65_HUMAN-N6-acetyllysine310 relationship: transforms_into CCO:B0041212 ! TF65_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0041213 ! TF65_HUMAN-Phosphothreonine435 relationship: transforms_into CCO:B0041214 ! TF65_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0041215 ! TF65_HUMAN-Phosphothreonine505 relationship: transforms_into CCO:B0041216 ! TF65_HUMAN-Phosphoserine529 relationship: transforms_into CCO:B0041217 ! TF65_HUMAN-Phosphoserine536 [Term] id: CCO:B0005866 name: RANB3_HUMAN def: "Ran-binding protein 3" [UniProtKB:Q9H6Z4] synonym: "RanBP3" EXACT [UniProtKB:Q9H6Z4] xref: EMBL:AAC14485.1 xref: EMBL:AAH04349.1 xref: EMBL:BAB15106.1 xref: EMBL:CAA69956.1 xref: EMBL:CAA69957.1 xref: EMBL:CAB43293.1 xref: UniProtKB:O60405 xref: UniProtKB:O75759 xref: UniProtKB:O75760 xref: UniProtKB:Q9BT47 xref: UniProtKB:Q9H6Z4 xref: UniProtKB:Q9UG74 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005423 ! RANBP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007153 ! ranbp3-ran-1 physical interaction relationship: participates_in CCO:I0007154 ! ranbp3-rcc1-1 physical interaction relationship: participates_in CCO:I0007298 ! rcc1-ranbp3-1 physical interaction relationship: transforms_into CCO:B0013692 ! RANB3_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0013693 ! RANB3_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0013694 ! RANB3_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0013695 ! RANB3_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0013696 ! RANB3_HUMAN-Phosphotyrosine115 relationship: transforms_into CCO:B0013697 ! RANB3_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0013698 ! RANB3_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0013699 ! RANB3_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0013700 ! RANB3_HUMAN-Phosphoserine359 relationship: transforms_into CCO:B0036025 ! RANB3_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0069726 ! RANB3_HUMAN-Phosphothreonine124 relationship: transforms_into CCO:B0069727 ! RANB3_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0069728 ! RANB3_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0069729 ! RANB3_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0069730 ! RANB3_HUMAN-Phosphoserine539 [Term] id: CCO:B0005867 name: XPO1_HUMAN def: "Exportin-1" [UniProtKB:O14980] synonym: "Chromosome region maintenance 1 protein homolog" EXACT [UniProtKB:O14980] synonym: "Exp1" EXACT [UniProtKB:O14980] xref: EMBL:AAH32847.1 xref: EMBL:AAY14949.1 xref: EMBL:BAA23415.1 xref: EMBL:BAF82609.1 xref: EMBL:CAA69905.2 xref: EMBL:CAH18695.1 xref: EMBL:CAH56174.1 xref: EMBL:EAW99993.1 xref: UniProtKB:A6NL14 xref: UniProtKB:A8K1K5 xref: UniProtKB:O14980 xref: UniProtKB:Q63HP8 xref: UniProtKB:Q68CP3 xref: UniProtKB:Q99433 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005940 ! XPO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007155 ! rcc1-xpo1-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007607 ! phb-tp53-3 physical interaction relationship: participates_in CCO:I0007608 ! tp53-phb- physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016504 ! ikbkg-crm1 physical interaction relationship: transforms_into CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 [Term] id: CCO:B0005868 name: FGFR1_HUMAN def: "Basic fibroblast growth factor receptor 1 precursor" [UniProtKB:P11362] synonym: "bFGF-R" EXACT [UniProtKB:P11362] synonym: "c-fgr" EXACT [UniProtKB:P11362] synonym: "CD331 antigen" EXACT [UniProtKB:P11362] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P11362] synonym: "FGFR-1" EXACT [UniProtKB:P11362] synonym: "Fms-like tyrosine kinase 2" EXACT [UniProtKB:P11362] xref: EMBL:AAA35835.1 xref: EMBL:AAA35836.1 xref: EMBL:AAA35837.1 xref: EMBL:AAA35838.1 xref: EMBL:AAA35839.1 xref: EMBL:AAA35840.1 xref: EMBL:AAA35958.1 xref: EMBL:AAA35959.1 xref: EMBL:AAA35960.1 xref: EMBL:AAA75007.1 xref: EMBL:AAH15035.1 xref: EMBL:AAH18128.1 xref: EMBL:AAS79322.1 xref: EMBL:CAA01958.1 xref: EMBL:CAA36101.1 xref: EMBL:CAA37015.1 xref: EMBL:CAA40400.1 xref: EMBL:CAA40401.1 xref: EMBL:CAA40402.1 xref: EMBL:CAA40403.1 xref: EMBL:CAA40404.1 xref: EMBL:CAA47375.1 xref: EMBL:CAA68679.1 xref: UniProtKB:P11362 xref: UniProtKB:P17049 xref: UniProtKB:Q02063 xref: UniProtKB:Q02065 xref: UniProtKB:Q14306 xref: UniProtKB:Q14307 xref: UniProtKB:Q8N685 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004642 ! FGFR1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001344 ! fibroblast growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007164 ! fgf2-fgfr1-2 direct interaction relationship: participates_in CCO:I0007497 ! fgf2-fgfr1-1 direct interaction relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: transforms_into CCO:B0011877 ! FGFR1_HUMAN-Phosphotyrosine654 relationship: transforms_into CCO:B0011878 ! FGFR1_HUMAN-Phosphotyrosine766 relationship: transforms_into CCO:B0066184 ! FGFR1_HUMAN-Phosphotyrosine653 [Term] id: CCO:B0005869 name: UBE2N_HUMAN def: "Ubiquitin-conjugating enzyme E2 N" [UniProtKB:P61088] synonym: "Bendless-like ubiquitin-conjugating enzyme" EXACT [UniProtKB:P61088] synonym: "EC 6.3.2.19" EXACT [UniProtKB:P61088] synonym: "Ubc13" EXACT [UniProtKB:P61088] synonym: "Ubiquitin carrier protein N" EXACT [UniProtKB:P61088] synonym: "Ubiquitin-protein ligase N" EXACT [UniProtKB:P61088] xref: EMBL:AAH00396.1 xref: EMBL:AAH03365.1 xref: EMBL:AAI08705.1 xref: EMBL:AAP35519.1 xref: EMBL:BAA11675.1 xref: UniProtKB:P61088 xref: UniProtKB:Q16781 xref: UniProtKB:Q53Y81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005861 ! UBE2N_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001220 ! UBC13-MMS2 complex relationship: participates_in CCO:I0007165 ! ube2n-ube2v2-1 direct interaction relationship: participates_in CCO:P0000643 ! regulation of DNA repair relationship: participates_in CCO:P0001369 ! positive regulation of histone modification relationship: participates_in CCO:P0001807 ! regulation of histone ubiquitination relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002527 ! positive regulation of DNA repair relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0005870 name: TGFA_HUMAN def: "Protransforming growth factor alpha precursor" [UniProtKB:P01135] xref: EMBL:AAA52530.1 xref: EMBL:AAA61157.1 xref: EMBL:AAA61159.1 xref: EMBL:AAF13491.1 xref: EMBL:CAA49806.1 xref: UniProtKB:P01135 xref: UniProtKB:Q15577 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005772 ! TGFA_human relationship: has_function CCO:F0000251 ! glycoprotein binding relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001457 ! epidermal growth factor receptor activating ligand activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007167 ! egfr-tgfa-1 direct interaction relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002529 ! positive regulation of epidermal growth factor receptor activity relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0005871 name: ANT3_HUMAN def: "Antithrombin-III precursor" [UniProtKB:P01008] synonym: "ATIII" EXACT [UniProtKB:P01008] xref: EMBL:AAA51793.1 xref: EMBL:AAA51794.1 xref: EMBL:AAA51796.1 xref: EMBL:AAB40025.1 xref: EMBL:AAG35525.1 xref: EMBL:AAK60337.1 xref: EMBL:CAA48690.1 xref: UniProtKB:P01008 xref: UniProtKB:P78439 xref: UniProtKB:P78447 xref: UniProtKB:Q13815 xref: UniProtKB:Q7KZ43 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004067 ! SERPINC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007168 ! f2-f2-1 physical interaction [Term] id: CCO:B0005872 name: AAPK1_HUMAN def: "5'-AMP-activated protein kinase catalytic subunit alpha-1" [UniProtKB:Q13131] synonym: "AMPK alpha-1 chain" EXACT [UniProtKB:Q13131] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13131] xref: EMBL:AAA64850.1 xref: EMBL:AAD43027.1 xref: EMBL:AAH37303.1 xref: EMBL:AAH48980.1 xref: EMBL:BAA36547.1 xref: EMBL:CAA73361.1 xref: UniProtKB:O00286 xref: UniProtKB:Q13131 xref: UniProtKB:Q5D0E1 xref: UniProtKB:Q86VS1 xref: UniProtKB:Q9UNQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004008 ! PRKAA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002387 ! positive regulation of cholesterol biosynthetic process relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis relationship: participates_in CCO:P0002684 ! negative regulation of glucosylceramide biosynthetic process relationship: transforms_into CCO:B0010388 ! AAPK1_HUMAN-Phosphothreonine174 relationship: transforms_into CCO:B0010389 ! AAPK1_HUMAN-Phosphoserine175 relationship: transforms_into CCO:B0010390 ! AAPK1_HUMAN-Phosphoserine499 relationship: transforms_into CCO:B0026336 ! AAPK1_HUMAN-Phosphoserine487 relationship: transforms_into CCO:B0048151 ! AAPK1_HUMAN-Phosphothreonine373 relationship: transforms_into CCO:B0065252 ! AAPK1_HUMAN-Phosphothreonine260 relationship: transforms_into CCO:B0065253 ! AAPK1_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0065254 ! AAPK1_HUMAN-Phosphotyrosine433 relationship: transforms_into CCO:B0065255 ! AAPK1_HUMAN-Phosphoserine477 relationship: transforms_into CCO:B0065256 ! AAPK1_HUMAN-Phosphothreonine481 [Term] id: CCO:B0005873 name: SN1L2_HUMAN def: "Serine/threonine-protein kinase SNF1-like kinase 2" [UniProtKB:Q9H0K1] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9H0K1] synonym: "Qin-induced kinase" EXACT [UniProtKB:Q9H0K1] synonym: "Salt-inducible protein kinase 2" EXACT [UniProtKB:Q9H0K1] synonym: "SIK-2" EXACT [UniProtKB:Q9H0K1] synonym: "SIK2" EXACT [UniProtKB:Q9H0K1] xref: EMBL:AAH13612.1 xref: EMBL:AAH78150.1 xref: EMBL:AAI13460.1 xref: EMBL:AAI17184.1 xref: EMBL:BAA34501.3 xref: EMBL:BAB91442.1 xref: EMBL:CAB66698.1 xref: UniProtKB:O94878 xref: UniProtKB:Q17RV0 xref: UniProtKB:Q6AZE2 xref: UniProtKB:Q76N03 xref: UniProtKB:Q8NCV7 xref: UniProtKB:Q96CZ8 xref: UniProtKB:Q9H0K1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005642 ! SNF1LK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007181 ! snf1l2-2aab-1 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0002704 ! regulation of insulin receptor signaling pathway relationship: transforms_into CCO:B0014133 ! SN1L2_HUMAN-Phosphothreonine175 relationship: transforms_into CCO:B0014134 ! SN1L2_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0014135 ! SN1L2_HUMAN-Phosphoserine587 [Term] id: CCO:B0005874 name: NUAK2_HUMAN def: "NUAK family SNF1-like kinase 2" [UniProtKB:Q9H093] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9H093] synonym: "SNARK" EXACT [UniProtKB:Q9H093] synonym: "SNF1/AMP kinase-related kinase" EXACT [UniProtKB:Q9H093] xref: EMBL:AAH17306.1 xref: EMBL:BAC11234.1 xref: EMBL:CAB66825.1 xref: UniProtKB:Q9H093 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005219 ! NUAK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007182 ! nuak2-cdc37-1 physical interaction relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0013264 ! NUAK2_HUMAN-Phosphothreonine208 relationship: transforms_into CCO:B0013265 ! NUAK2_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0013266 ! NUAK2_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0013267 ! NUAK2_HUMAN-Phosphoserine386 relationship: transforms_into CCO:B0013268 ! NUAK2_HUMAN-Phosphoserine585 [Term] id: CCO:B0005875 name: CD59_HUMAN def: "CD59 glycoprotein precursor" [UniProtKB:P13987] synonym: "1F5 antigen" EXACT [UniProtKB:P13987] synonym: "20 kDa homologous restriction factor" EXACT [UniProtKB:P13987] synonym: "CD59 antigen" EXACT [UniProtKB:P13987] synonym: "HRF-20" EXACT [UniProtKB:P13987] synonym: "HRF20" EXACT [UniProtKB:P13987] synonym: "MAC-inhibitory protein" EXACT [UniProtKB:P13987] synonym: "MAC-IP" EXACT [UniProtKB:P13987] synonym: "MACIF" EXACT [UniProtKB:P13987] synonym: "MEM43 antigen" EXACT [UniProtKB:P13987] synonym: "Membrane attack complex inhibition factor" EXACT [UniProtKB:P13987] synonym: "Membrane inhibitor of reactive lysis" EXACT [UniProtKB:P13987] synonym: "MIRL" EXACT [UniProtKB:P13987] synonym: "Protectin" EXACT [UniProtKB:P13987] xref: EMBL:AAA51952.1 xref: EMBL:AAA60543.1 xref: EMBL:AAA60957.1 xref: EMBL:AAA88793.1 xref: EMBL:AAH01506.1 xref: EMBL:AAP35768.1 xref: EMBL:CAA34467.1 xref: EMBL:CAA35059.1 xref: EMBL:CAA78486.1 xref: UniProtKB:P13987 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004279 ! CD59_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007198 ! egfr-cd59-1 direct interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0005876 name: CAB39_HUMAN def: "Calcium-binding protein 39" [UniProtKB:Q9Y376] synonym: "Protein Mo25" EXACT [UniProtKB:Q9Y376] xref: EMBL:AAD34061.1 xref: EMBL:AAF14873.1 xref: EMBL:AAH20570.1 xref: UniProtKB:Q9Y376 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004202 ! CAB39_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007201 ! stk11-mo25-1 physical interaction relationship: participates_in CCO:I0007209 ! mo25-als2cr2-1 physical interaction relationship: participates_in CCO:I0007222 ! mo25-stk11-1 physical interaction [Term] id: CCO:B0005877 name: PNMA1_HUMAN def: "Paraneoplastic antigen Ma1" [UniProtKB:Q8ND90] synonym: "37 kDa neuronal protein" EXACT [UniProtKB:Q8ND90] synonym: "Neuron- and testis-specific protein 1" EXACT [UniProtKB:Q8ND90] xref: EMBL:AAD13810.3 xref: EMBL:AAH39577.1 xref: EMBL:AAN05100.1 xref: EMBL:CAD38995.1 xref: UniProtKB:O95144 xref: UniProtKB:Q8ND90 xref: UniProtKB:Q8NG07 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005348 ! PNMA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007227 ! pard6b-pnma1-1 physical interaction relationship: participates_in CCO:I0007228 ! pnma1-pard6b-1 physical interaction relationship: participates_in CCO:I0007230 ! pard6b-pard3-2 physical interaction relationship: participates_in CCO:I0007231 ! pard3-pnma1-1 physical interaction relationship: participates_in CCO:I0007232 ! pnma1-pard3-1 physical interaction relationship: participates_in CCO:I0018283 ! pnma1-mark4-1 physical interaction relationship: participates_in CCO:I0018284 ! pnma1-prcki-1 physical interaction [Term] id: CCO:B0005878 name: GABPA_HUMAN def: "GA-binding protein alpha chain" [UniProtKB:Q06546] synonym: "GABP subunit alpha" EXACT [UniProtKB:Q06546] synonym: "Nuclear respiratory factor 2 subunit alpha" EXACT [UniProtKB:Q06546] synonym: "Transcription factor E4TF1-60" EXACT [UniProtKB:Q06546] xref: EMBL:AAA65706.1 xref: EMBL:BAA02575.1 xref: UniProtKB:Q06546 xref: UniProtKB:Q12939 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004679 ! GABPA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007262 ! hcfc1-gabpa-1 physical interaction relationship: participates_in CCO:I0007263 ! hcfc1-gabp2-4 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0005879 name: ATRX_HUMAN def: "Transcriptional regulator ATRX" [UniProtKB:P46100] synonym: "ATP-dependent helicase ATRX" EXACT [UniProtKB:P46100] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P46100] synonym: "X-linked helicase II" EXACT [UniProtKB:P46100] synonym: "X-linked nuclear protein" EXACT [UniProtKB:P46100] synonym: "XNP" EXACT [UniProtKB:P46100] synonym: "Znf-HX" EXACT [UniProtKB:P46100] xref: EMBL:AAA20872.1 xref: EMBL:AAB40698.1 xref: EMBL:AAB40699.1 xref: EMBL:AAB40700.1 xref: EMBL:AAB49969.1 xref: EMBL:AAB49970.2 xref: EMBL:AAB49971.2 xref: EMBL:AAC50069.1 xref: EMBL:AAC51655.1 xref: EMBL:AAC51657.1 xref: EMBL:BAC80270.1 xref: EMBL:BAC80271.1 xref: EMBL:BAC80272.1 xref: EMBL:BAC80273.1 xref: EMBL:BAC80274.1 xref: EMBL:BAC80275.1 xref: EMBL:BAC80276.1 xref: EMBL:BAC80277.1 xref: EMBL:BAC80278.1 xref: EMBL:BAC80279.1 xref: EMBL:BAC80280.1 xref: EMBL:BAC80281.1 xref: EMBL:BAC80282.1 xref: EMBL:BAC80283.1 xref: EMBL:BAC80284.1 xref: EMBL:BAC80285.1 xref: EMBL:BAC80286.1 xref: EMBL:BAC80287.1 xref: EMBL:BAC80288.1 xref: EMBL:BAC80289.1 xref: EMBL:BAC81110.1 xref: EMBL:BAD92165.1 xref: EMBL:BAD92782.1 xref: EMBL:CAA58711.1 xref: EMBL:CAB90351.2 xref: EMBL:CAI40710.1 xref: EMBL:CAI42674.1 xref: EMBL:CAI42675.1 xref: EMBL:CAI43115.1 xref: EMBL:CAI43116.1 xref: UniProtKB:P46100 xref: UniProtKB:P51068 xref: UniProtKB:Q15886 xref: UniProtKB:Q59FB5 xref: UniProtKB:Q59H31 xref: UniProtKB:Q5H9A2 xref: UniProtKB:Q5JWI4 xref: UniProtKB:Q7Z2J1 xref: UniProtKB:Q9H0Z1 xref: UniProtKB:Q9NTS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004123 ! ATRX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007270 ! nek1-xh2-1 physical interaction relationship: participates_in CCO:I0008196 ! atrx-ptn physical interaction relationship: participates_in CCO:I0019919 ! atrx-kiaa1377 physical interaction relationship: participates_in CCO:I0019920 ! atrx-luc7l2 physical interaction relationship: participates_in CCO:I0019921 ! atrx-ptpn4 physical interaction relationship: participates_in CCO:P0000646 ! DNA methylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010695 ! ATRX_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0010696 ! ATRX_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0010697 ! ATRX_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0010698 ! ATRX_HUMAN-Phosphothreonine87 relationship: transforms_into CCO:B0010699 ! ATRX_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0010700 ! ATRX_HUMAN-Phosphoserine634 relationship: transforms_into CCO:B0010701 ! ATRX_HUMAN-Phosphoserine729 relationship: transforms_into CCO:B0010702 ! ATRX_HUMAN-Phosphoserine731 relationship: transforms_into CCO:B0010703 ! ATRX_HUMAN-Phosphoserine849 relationship: transforms_into CCO:B0010704 ! ATRX_HUMAN-Phosphoserine850 relationship: transforms_into CCO:B0010705 ! ATRX_HUMAN-Phosphoserine871 relationship: transforms_into CCO:B0010706 ! ATRX_HUMAN-Phosphoserine1348 relationship: transforms_into CCO:B0010707 ! ATRX_HUMAN-Phosphoserine1352 relationship: transforms_into CCO:B0010708 ! ATRX_HUMAN-Phosphoserine1527 [Term] id: CCO:B0005880 name: KIF3A_HUMAN def: "Kinesin-like protein KIF3A" [UniProtKB:Q9Y496] synonym: "Microtubule plus end-directed kinesin motor 3A" EXACT [UniProtKB:Q9Y496] xref: EMBL:AAC04475.1 xref: EMBL:AAC72294.1 xref: EMBL:AAH45542.1 xref: EMBL:BAD93017.1 xref: UniProtKB:Q59EN1 xref: UniProtKB:Q86XE9 xref: UniProtKB:Q9Y496 xref: UniProtKB:Q9Y6V4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004948 ! KIF3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007273 ! nek1-kif3a physical interaction relationship: transforms_into CCO:B0012607 ! KIF3A_HUMAN-Phosphoserine690 [Term] id: CCO:B0005881 name: CTNL1_HUMAN def: "Alpha-catulin" [UniProtKB:Q9UBT7] synonym: "ACRP" EXACT [UniProtKB:Q9UBT7] synonym: "Alpha-catenin-related protein" EXACT [UniProtKB:Q9UBT7] synonym: "Catenin alpha-like protein 1" EXACT [UniProtKB:Q9UBT7] xref: EMBL:AAC26011.1 xref: EMBL:AAC27693.1 xref: EMBL:AAC69576.1 xref: EMBL:AAC83460.1 xref: EMBL:AAF07819.1 xref: EMBL:AAF07820.1 xref: EMBL:AAF07821.1 xref: EMBL:AAI17209.1 xref: EMBL:AAI17235.1 xref: EMBL:AAR92479.1 xref: EMBL:BAD96950.1 xref: EMBL:CAB43238.1 xref: EMBL:CAI39471.1 xref: EMBL:CAI39472.1 xref: UniProtKB:O76084 xref: UniProtKB:Q53FQ2 xref: UniProtKB:Q5JTQ7 xref: UniProtKB:Q5JTQ8 xref: UniProtKB:Q9UBT7 xref: UniProtKB:Q9Y401 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004419 ! CTNNAL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007276 ! nek1-ctnnal1-1 physical interaction relationship: transforms_into CCO:B0064587 ! CTNL1_HUMAN-Phosphoserine538 [Term] id: CCO:B0005882 name: DPOD4_HUMAN def: "DNA polymerase delta subunit 4" [UniProtKB:Q9HCU8] synonym: "DNA polymerase delta subunit p12" EXACT [UniProtKB:Q9HCU8] xref: EMBL:AAG08966.1 xref: EMBL:AAX09676.1 xref: UniProtKB:Q9HCU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004504 ! POLD4_human relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0007289 ! pold1-pold2-4 physical interaction relationship: participates_in CCO:I0007588 ! pold1-pold2-1 physical interaction relationship: participates_in CCO:I0007590 ! pold1-pold4-1 direct interaction relationship: participates_in CCO:I0007910 ! pold1-pold2-6 physical interaction relationship: participates_in CCO:I0007911 ! pold1-pold2-7 physical interaction relationship: participates_in CCO:I0007912 ! dpol-delta_human physical interaction relationship: participates_in CCO:I0007968 ! pold1pold2-8 physical interaction relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0005883 name: DPOD2_HUMAN def: "DNA polymerase delta subunit 2" [UniProtKB:P49005] synonym: "DNA polymerase delta subunit p50" EXACT [UniProtKB:P49005] synonym: "EC 2.7.7.7" EXACT [UniProtKB:P49005] xref: EMBL:AAC50216.1 xref: EMBL:AAG09763.1 xref: EMBL:AAH00459.1 xref: EMBL:AAM51148.1 xref: UniProtKB:P49005 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004502 ! POLD2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0007289 ! pold1-pold2-4 physical interaction relationship: participates_in CCO:I0007290 ! pold1-pold2-5 physical interaction relationship: participates_in CCO:I0007588 ! pold1-pold2-1 physical interaction relationship: participates_in CCO:I0007589 ! pold1-pold2-3 physical interaction relationship: participates_in CCO:I0007910 ! pold1-pold2-6 physical interaction relationship: participates_in CCO:I0007911 ! pold1-pold2-7 physical interaction relationship: participates_in CCO:I0007912 ! dpol-delta_human physical interaction relationship: participates_in CCO:I0017323 ! lsm6-pold2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0005884 name: DPOD3_HUMAN def: "DNA polymerase delta subunit 3" [UniProtKB:Q15054] synonym: "DNA polymerase delta subunit p66" EXACT [UniProtKB:Q15054] xref: EMBL:BAA05039.1 xref: UniProtKB:Q15054 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004503 ! POLD3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0001800 ! delta DNA polymerase complex relationship: participates_in CCO:I0007289 ! pold1-pold2-4 physical interaction relationship: participates_in CCO:I0007588 ! pold1-pold2-1 physical interaction relationship: participates_in CCO:I0007910 ! pold1-pold2-6 physical interaction relationship: participates_in CCO:I0007911 ! pold1-pold2-7 physical interaction relationship: participates_in CCO:I0007912 ! dpol-delta_human physical interaction relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0011572 ! DPOD3_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0011573 ! DPOD3_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0011574 ! DPOD3_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0011575 ! DPOD3_HUMAN-Phosphothreonine411 relationship: transforms_into CCO:B0011576 ! DPOD3_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0064854 ! DPOD3_HUMAN-Phosphoserine458 [Term] id: CCO:B0005885 name: DPOE3_HUMAN def: "DNA polymerase epsilon subunit 3" [UniProtKB:Q9NRF9] synonym: "Arsenic-transactivated protein" EXACT [UniProtKB:Q9NRF9] synonym: "AsTP" EXACT [UniProtKB:Q9NRF9] synonym: "CHRAC-17" EXACT [UniProtKB:Q9NRF9] synonym: "Chromatin accessibility complex 17" EXACT [UniProtKB:Q9NRF9] synonym: "DNA polymerase epsilon subunit p17" EXACT [UniProtKB:Q9NRF9] synonym: "DNA polymerase II subunit 3" EXACT [UniProtKB:Q9NRF9] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9NRF9] synonym: "HuCHRAC17" EXACT [UniProtKB:Q9NRF9] xref: EMBL:AAF72417.1 xref: EMBL:AAF90133.1 xref: EMBL:AAH03166.1 xref: EMBL:AAH04170.1 xref: EMBL:AAU15052.1 xref: EMBL:AAY57326.1 xref: EMBL:BAC11099.1 xref: EMBL:BAC11190.1 xref: EMBL:BAC11206.1 xref: EMBL:CAH70100.1 xref: UniProtKB:Q5W0U1 xref: UniProtKB:Q8N758 xref: UniProtKB:Q8NCE5 xref: UniProtKB:Q9NR32 xref: UniProtKB:Q9NRF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004507 ! POLE3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007291 ! pole3-pole4-6 physical interaction relationship: participates_in CCO:I0007363 ! pole3-pole4-3 physical interaction relationship: participates_in CCO:I0007364 ! pole3-pole4-4 physical interaction relationship: participates_in CCO:I0007913 ! dpol-epsilon_human physical interaction relationship: participates_in CCO:I0015149 ! drap1-pole3 physical interaction relationship: participates_in CCO:I0015581 ! dr1-pole3 physical interaction relationship: participates_in CCO:I0018364 ! pole3-pole4-1 physical interaction relationship: participates_in CCO:I0018365 ! pole3-pole4-2 physical interaction relationship: participates_in CCO:I0018528 ! pole3-pole4-5 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0011578 ! DPOE3_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0064855 ! DPOE3_HUMAN-Phosphothreonine83 [Term] id: CCO:B0005886 name: DAZ1_HUMAN def: "Deleted in azoospermia protein 1" [UniProtKB:Q9NQZ3] xref: EMBL:AAF91405.1 xref: EMBL:AAF91406.1 xref: UniProtKB:Q9NQZ3 xref: UniProtKB:Q9NQZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004438 ! DAZ1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001952 ! translation activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007300 ! daz1-boll-1 physical interaction relationship: participates_in CCO:I0017767 ! pum2-dazl1-4 physical interaction relationship: participates_in CCO:I0017768 ! dazl1-pum2-4 physical interaction relationship: participates_in CCO:I0018391 ! daz1-pum2-1 physical interaction relationship: participates_in CCO:I0018392 ! daz1-pum2-3 physical interaction relationship: participates_in CCO:I0018393 ! daz1-dzip1-1 physical interaction relationship: participates_in CCO:I0018394 ! daz1-dzip3-1 physical interaction relationship: participates_in CCO:I0018395 ! daz1-dazl-1 physical interaction relationship: participates_in CCO:I0018396 ! daz1-qk3-1 physical interaction relationship: participates_in CCO:I0018702 ! pum2-daz1-1 physical interaction relationship: participates_in CCO:P0002631 ! positive regulation of translational initiation [Term] id: CCO:B0005887 name: RFC1_HUMAN def: "Replication factor C subunit 1" [UniProtKB:P35251] synonym: "A1 140 kDa subunit" EXACT [UniProtKB:P35251] synonym: "Activator 1 140 kDa subunit" EXACT [UniProtKB:P35251] synonym: "Activator 1 large subunit" EXACT [UniProtKB:P35251] synonym: "Activator 1 subunit 1" EXACT [UniProtKB:P35251] synonym: "DNA-binding protein PO-GA" EXACT [UniProtKB:P35251] synonym: "Replication factor C large subunit" EXACT [UniProtKB:P35251] synonym: "RF-C 140 kDa subunit" EXACT [UniProtKB:P35251] xref: EMBL:AAA16121.1 xref: EMBL:AAB99788.1 xref: EMBL:AAH35297.1 xref: EMBL:AAH51751.1 xref: EMBL:AAH51786.1 xref: EMBL:AAS94325.1 xref: EMBL:CAA80355.1 xref: UniProtKB:P35251 xref: UniProtKB:Q5XKF5 xref: UniProtKB:Q6PKU0 xref: UniProtKB:Q86V41 xref: UniProtKB:Q86V46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005472 ! RFC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007307 ! smc1-rfc1-1 physical interaction relationship: participates_in CCO:I0015869 ! rfc1-rfc2-2 physical interaction relationship: participates_in CCO:I0015870 ! rfc1-rfc2-3 physical interaction relationship: participates_in CCO:I0015871 ! rfc1-rfc2-4 physical interaction relationship: participates_in CCO:I0015875 ! rfc1-rfc3-1 physical interaction relationship: participates_in CCO:I0015879 ! rfc4-rfc5-1 physical interaction relationship: participates_in CCO:I0015907 ! rfc1-rfc2-1 physical interaction relationship: participates_in CCO:I0019330 ! rfc_human physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: transforms_into CCO:B0013827 ! RFC1_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0013828 ! RFC1_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0013829 ! RFC1_HUMAN-Phosphoserine73 relationship: transforms_into CCO:B0013830 ! RFC1_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0013831 ! RFC1_HUMAN-Phosphothreonine110 relationship: transforms_into CCO:B0013832 ! RFC1_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0013833 ! RFC1_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0013834 ! RFC1_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0013835 ! RFC1_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0048378 ! RFC1_HUMAN-Phosphotyrosine670 relationship: transforms_into CCO:B0048379 ! RFC1_HUMAN-Phosphotyrosine672 relationship: transforms_into CCO:B0069895 ! RFC1_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0069896 ! RFC1_HUMAN-Phosphothreonine171 relationship: transforms_into CCO:B0069897 ! RFC1_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0069898 ! RFC1_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0069899 ! RFC1_HUMAN-Phosphoserine312 [Term] id: CCO:B0005888 name: BHLH2_HUMAN def: "Class B basic helix-loop-helix protein 2" [UniProtKB:O14503] synonym: "bHLHB2" EXACT [UniProtKB:O14503] synonym: "DEC1" EXACT [UniProtKB:O14503] synonym: "Differentially expressed in chondrocytes protein 1" EXACT [UniProtKB:O14503] synonym: "Enhancer-of-split and hairy-related protein 2" EXACT [UniProtKB:O14503] synonym: "SHARP-2" EXACT [UniProtKB:O14503] synonym: "Stimulated by retinoic acid gene 13 protein" EXACT [UniProtKB:O14503] xref: EMBL:AAH82238.1 xref: EMBL:AAK49525.1 xref: EMBL:BAA21720.1 xref: EMBL:BAB18565.1 xref: UniProtKB:O14503 xref: UniProtKB:Q96TD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004159 ! BHLHB2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007316 ! bhlbh2-ube2i physical interaction relationship: participates_in CCO:I0007476 ! bhlbh2-ube2i-2 physical interaction relationship: participates_in CCO:I0007511 ! bhlbh2-ube2i-1 physical interaction relationship: participates_in CCO:I0019568 ! bhlhb2-chd3 physical interaction relationship: participates_in CCO:I0019569 ! bhlhb2-zhx1 physical interaction relationship: participates_in CCO:I0019668 ! bhlhb2-setdb1 physical interaction relationship: participates_in CCO:I0019669 ! bhlhb2-vim physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002785 ! regulation of neuronal synaptic plasticity [Term] id: CCO:B0005889 name: TAP1_HUMAN def: "Antigen peptide transporter 1" [UniProtKB:Q03518] synonym: "APT1" EXACT [UniProtKB:Q03518] synonym: "ATP-binding cassette sub-family B member 2" EXACT [UniProtKB:Q03518] synonym: "Peptide supply factor 1" EXACT [UniProtKB:Q03518] synonym: "Peptide transporter involved in antigen processing 1" EXACT [UniProtKB:Q03518] synonym: "Peptide transporter PSF1" EXACT [UniProtKB:Q03518] synonym: "Peptide transporter TAP1" EXACT [UniProtKB:Q03518] synonym: "PSF-1" EXACT [UniProtKB:Q03518] xref: EMBL:AAC12902.1 xref: EMBL:AAC12903.1 xref: EMBL:AAC12904.1 xref: EMBL:AAC12905.1 xref: EMBL:AAC12906.1 xref: EMBL:AAD14056.1 xref: EMBL:AAH14081.1 xref: EMBL:CAA40740.1 xref: EMBL:CAA40741.1 xref: EMBL:CAA47025.1 xref: EMBL:CAA60785.1 xref: EMBL:CAI17714.1 xref: EMBL:CAI18140.1 xref: EMBL:CAI18626.1 xref: EMBL:CAQ08449.1 xref: EMBL:CAQ08495.1 xref: EMBL:CAQ08906.1 xref: EMBL:CAQ10287.1 xref: EMBL:EAX03647.1 xref: UniProtKB:Q03518 xref: UniProtKB:Q16149 xref: UniProtKB:Q96CP4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005729 ! TAP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002671 ! peptide transporter activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007317 ! tap1-calr direct interaction relationship: participates_in CCO:I0007710 ! tap1-b2m physical interaction relationship: participates_in CCO:I0015868 ! tap1-pd1a3-2 direct interaction relationship: participates_in CCO:I0018264 ! tap1-pd1a3-1 direct interaction relationship: participates_in CCO:I0018405 ! tap1-pd1a3 direct interaction [Term] id: CCO:B0005891 name: MAPK5_HUMAN def: "MAP kinase-activated protein kinase 5" [UniProtKB:Q8IW41] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8IW41] synonym: "MAPK-activated protein kinase 5" EXACT [UniProtKB:Q8IW41] synonym: "MAPKAP kinase 5" EXACT [UniProtKB:Q8IW41] synonym: "p38-regulated/activated protein kinase" EXACT [UniProtKB:Q8IW41] xref: EMBL:AAC39863.1 xref: EMBL:AAH00833.1 xref: EMBL:AAH41049.1 xref: EMBL:AAH47284.2 xref: EMBL:CAB53747.1 xref: UniProtKB:O60491 xref: UniProtKB:Q86X46 xref: UniProtKB:Q8IW41 xref: UniProtKB:Q9BVX9 xref: UniProtKB:Q9UG86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005023 ! MAPKAPK5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007322 ! mapkapk5-tp53 phosphorylation relationship: participates_in CCO:I0007324 ! mapkapk5-tp53-1 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0012762 ! MAPK5_HUMAN-Phosphothreonine182 [Term] id: CCO:B0005892 name: MK11_HUMAN def: "Mitogen-activated protein kinase 11" [UniProtKB:Q15759] synonym: "EC 2.7.11.24" EXACT [UniProtKB:Q15759] synonym: "MAP kinase p38 beta" EXACT [UniProtKB:Q15759] synonym: "Mitogen-activated protein kinase p38 beta" EXACT [UniProtKB:Q15759] synonym: "p38-2" EXACT [UniProtKB:Q15759] synonym: "p38b" EXACT [UniProtKB:Q15759] synonym: "Stress-activated protein kinase 2" EXACT [UniProtKB:Q15759] xref: EMBL:AAB05036.1 xref: EMBL:AAB66313.1 xref: EMBL:AAC12714.1 xref: EMBL:AAC51250.1 xref: EMBL:AAC51373.1 xref: EMBL:AAH27933.1 xref: EMBL:ABB72677.1 xref: EMBL:CAA74792.1 xref: EMBL:CAB51539.1 xref: EMBL:CAG30400.1 xref: UniProtKB:O00284 xref: UniProtKB:O15472 xref: UniProtKB:Q15759 xref: UniProtKB:Q2XNF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005094 ! MAPK11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001844 ! MP kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0007325 ! mapk11-tp53-1 phosphorylation relationship: participates_in CCO:I0018412 ! mapk11-atf2 phosphorylation relationship: participates_in CCO:I0018579 ! mapk11-sp1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0012954 ! MK11_HUMAN-Phosphothreonine180 relationship: transforms_into CCO:B0012955 ! MK11_HUMAN-Phosphotyrosine182 [Term] id: CCO:B0005893 name: NCOA6_HUMAN def: "Nuclear receptor coactivator 6" [UniProtKB:Q14686] synonym: "Activating signal cointegrator 2" EXACT [UniProtKB:Q14686] synonym: "Amplified in breast cancer protein 3" EXACT [UniProtKB:Q14686] synonym: "ASC-2" EXACT [UniProtKB:Q14686] synonym: "Cancer-amplified transcriptional coactivator ASC-2" EXACT [UniProtKB:Q14686] synonym: "NRC RAP250" EXACT [UniProtKB:Q14686] synonym: "Nuclear receptor coactivator RAP250" EXACT [UniProtKB:Q14686] synonym: "Nuclear receptor-activating protein, 250 kDa" EXACT [UniProtKB:Q14686] synonym: "Peroxisome proliferator-activated receptor-interacting protein" EXACT [UniProtKB:Q14686] synonym: "PPAR-interacting protein" EXACT [UniProtKB:Q14686] synonym: "PRIP" EXACT [UniProtKB:Q14686] synonym: "Thyroid hormone receptor-binding protein" EXACT [UniProtKB:Q14686] xref: EMBL:AAF13595.1 xref: EMBL:AAF16403.1 xref: EMBL:AAF37003.1 xref: EMBL:AAF71829.1 xref: EMBL:AAF78480.1 xref: EMBL:BAA11498.2 xref: EMBL:CAB92721.2 xref: EMBL:EAW76254.1 xref: UniProtKB:A6NLF1 xref: UniProtKB:Q14686 xref: UniProtKB:Q9NTZ9 xref: UniProtKB:Q9UH74 xref: UniProtKB:Q9UK86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005160 ! NCOA6_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0006286 ! retinoid X receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0007326 ! ncoa6-rara-1 physical interaction relationship: participates_in CCO:I0007327 ! ncoa6-rara-2 physical interaction relationship: participates_in CCO:I0017640 ! hrmt1l1-ncoa6-1 physical interaction relationship: participates_in CCO:I0017661 ! ncoa6-crebbp-1 physical interaction relationship: participates_in CCO:I0018413 ! ghr-ncoa6-1 physical interaction relationship: participates_in CCO:I0018414 ! ncoa6-thra-1 physical interaction relationship: participates_in CCO:I0018415 ! ncoa6-thrb-1 physical interaction relationship: participates_in CCO:I0018416 ! ncoa6-rxra-1 physical interaction relationship: participates_in CCO:I0018417 ! ncoa6-esr1-1 physical interaction relationship: participates_in CCO:I0018418 ! ncoa6-vdr-1 physical interaction relationship: participates_in CCO:I0018419 ! ncoa6-thra-2 physical interaction relationship: participates_in CCO:I0018420 ! ncoa6-thrb-2 physical interaction relationship: participates_in CCO:I0018421 ! ncoa6-rxra-2 physical interaction relationship: participates_in CCO:I0018422 ! ncoa6-esr1-2 physical interaction relationship: participates_in CCO:I0018423 ! ncoa6-ghr-2 physical interaction relationship: participates_in CCO:I0018424 ! ncoa6-vdr-2 physical interaction relationship: participates_in CCO:I0018425 ! ncoa6-ncoa6-1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0002128 ! glucocorticoid receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0013108 ! NCOA6_HUMAN-Phosphoserine884 relationship: transforms_into CCO:B0013109 ! NCOA6_HUMAN-Phosphothreonine1321 [Term] id: CCO:B0005894 name: HCK_HUMAN def: "Tyrosine-protein kinase HCK" [UniProtKB:P08631] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P08631] synonym: "Hemopoietic cell kinase" EXACT [UniProtKB:P08631] synonym: "p59-HCK/p60-HCK" EXACT [UniProtKB:P08631] xref: EMBL:AAA52643.1 xref: EMBL:AAA52644.1 xref: EMBL:AAH14435.2 xref: EMBL:AAH94847.2 xref: EMBL:AAI08931.2 xref: EMBL:AAI08932.2 xref: EMBL:AAI13855.2 xref: EMBL:AAI14464.2 xref: EMBL:BAB15482.1 xref: EMBL:CAA41565.2 xref: EMBL:CAI19694.1 xref: EMBL:CAI19695.1 xref: EMBL:CAI22966.1 xref: EMBL:CAI22967.1 xref: UniProtKB:P08631 xref: UniProtKB:Q29RX1 xref: UniProtKB:Q2VPE2 xref: UniProtKB:Q504R5 xref: UniProtKB:Q5T7K1 xref: UniProtKB:Q5T7K2 xref: UniProtKB:Q96CC0 xref: UniProtKB:Q9H5Y5 xref: UniProtKB:Q9NUA4 xref: UniProtKB:Q9UMJ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004783 ! HCK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007329 ! hck-dnm2-1 physical interaction relationship: participates_in CCO:I0007330 ! hck-p62-1 physical interaction relationship: participates_in CCO:I0007331 ! hck-cd2ap-1 physical interaction relationship: participates_in CCO:I0007964 ! hck-sam68-1 physical interaction relationship: participates_in CCO:I0016218 ! hck-elmo1-1 physical interaction relationship: participates_in CCO:I0017843 ! hck-elmo1-3 physical interaction relationship: participates_in CCO:I0018280 ! hck-elmo1-2 physical interaction relationship: participates_in CCO:I0018427 ! hck-sos1-1 physical interaction relationship: participates_in CCO:I0018428 ! hck-ddef1-1 physical interaction relationship: participates_in CCO:I0018429 ! hck-hnrpk-1 physical interaction relationship: participates_in CCO:I0018430 ! hck-evl-1 physical interaction relationship: participates_in CCO:I0018431 ! hck-sh3bp1-1 physical interaction relationship: participates_in CCO:I0018432 ! hck-tsg101-1 physical interaction relationship: participates_in CCO:I0018433 ! hck-pik3r2-1 physical interaction relationship: participates_in CCO:I0018434 ! hck-lcp2-1 physical interaction relationship: participates_in CCO:I0018435 ! hck-pik3r1-1 physical interaction relationship: participates_in CCO:I0018436 ! hck-elmo1-4 physical interaction relationship: transforms_into CCO:B0012154 ! HCK_HUMAN-Phosphotyrosine411 relationship: transforms_into CCO:B0066768 ! HCK_HUMAN-Phosphotyrosine209 [Term] id: CCO:B0005895 name: PBX2_HUMAN def: "Pre-B-cell leukemia transcription factor 2" [UniProtKB:P40425] synonym: "Homeobox protein PBX2" EXACT [UniProtKB:P40425] synonym: "Protein G17" EXACT [UniProtKB:P40425] xref: EMBL:AAB47490.1 xref: EMBL:AAH82261.1 xref: EMBL:BAA05957.1 xref: EMBL:CAA42503.1 xref: EMBL:CAA56717.1 xref: EMBL:CAI17539.1 xref: EMBL:CAI18358.1 xref: EMBL:CAI41814.1 xref: UniProtKB:P40425 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005273 ! PBX2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007332 ! pbx2-mcrs1 physical interaction relationship: participates_in CCO:I0007333 ! pbx2-p22 physical interaction relationship: participates_in CCO:I0018437 ! pbx2-ikbkap physical interaction relationship: participates_in CCO:I0018438 ! pbx2-gcn5l1 physical interaction relationship: participates_in CCO:I0018439 ! pbx2-smyd3 physical interaction relationship: participates_in CCO:I0018440 ! pbx2-zdhhc7 physical interaction relationship: participates_in CCO:I0018441 ! pbx2-kiaa0052 physical interaction relationship: participates_in CCO:I0018442 ! pbx2-nup62 physical interaction relationship: participates_in CCO:I0018443 ! pbx2-irsp53 physical interaction relationship: participates_in CCO:I0018444 ! pbx2-rpl4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013431 ! PBX2_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0048355 ! PBX2_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0069149 ! PBX2_HUMAN-Phosphoserine330 [Term] id: CCO:B0005896 name: STK19_HUMAN def: "Serine/threonine-protein kinase 19" [UniProtKB:P49842] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P49842] synonym: "Protein G11" EXACT [UniProtKB:P49842] synonym: "Protein RP1" EXACT [UniProtKB:P49842] xref: EMBL:AAA20120.1 xref: EMBL:AAA20122.1 xref: EMBL:AAA99716.1 xref: EMBL:AAB67976.1 xref: EMBL:CAA54565.1 xref: EMBL:CAA54622.1 xref: EMBL:CAA54623.1 xref: EMBL:CAB89303.1 xref: EMBL:CAB89304.1 xref: EMBL:CAI17470.2 xref: EMBL:CAM26056.1 xref: EMBL:CAM26064.1 xref: EMBL:CAQ07124.1 xref: EMBL:CAQ09283.1 xref: EMBL:CAQ10914.1 xref: EMBL:EAX03567.1 xref: UniProtKB:A6NFW8 xref: UniProtKB:B0QZR5 xref: UniProtKB:P49842 xref: UniProtKB:Q13159 xref: UniProtKB:Q31617 xref: UniProtKB:Q5ST75 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005692 ! STK19_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007334 ! stk19-pole physical interaction relationship: participates_in CCO:I0018447 ! stk19-sp3 physical interaction [Term] id: CCO:B0005897 name: CSK2B_HUMAN def: "Casein kinase II subunit beta" [UniProtKB:P67870] synonym: "CK II beta" EXACT [UniProtKB:P67870] synonym: "G5a" EXACT [UniProtKB:P67870] synonym: "Phosvitin" EXACT [UniProtKB:P67870] xref: EMBL:AAA52123.1 xref: EMBL:AAD18081.1 xref: EMBL:AAI12018.1 xref: EMBL:AAI12020.1 xref: EMBL:AAM50092.1 xref: EMBL:ABC40727.1 xref: EMBL:BAB63386.1 xref: EMBL:CAA34379.1 xref: EMBL:CAA34811.1 xref: EMBL:CAA40442.1 xref: EMBL:CAG46500.1 xref: EMBL:CAI17800.1 xref: EMBL:CAI18393.2 xref: EMBL:CAI18523.1 xref: EMBL:CAI96141.1 xref: UniProtKB:P07312 xref: UniProtKB:P13862 xref: UniProtKB:P67870 xref: UniProtKB:Q4VX47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004404 ! CSNK2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007336 ! csnk2b-csnk2a2 physical interaction relationship: participates_in CCO:I0015937 ! csnk2a1-was-1 phosphorylation relationship: participates_in CCO:I0015938 ! csnk2a1-was-2 phosphorylation relationship: participates_in CCO:I0018116 ! csnk2a1-csnk2b-1 direct interaction relationship: participates_in CCO:I0018455 ! csnk2b-lyn physical interaction relationship: participates_in CCO:I0018456 ! csnk2b-csnk2a1 physical interaction relationship: participates_in CCO:I0018457 ! csnk2b-csnk2b physical interaction relationship: participates_in CCO:I0018458 ! csnk2b-znhit1 physical interaction relationship: participates_in CCO:I0018459 ! csnk2b-mbd4 physical interaction relationship: participates_in CCO:I0018460 ! csnk2b-znf44 physical interaction relationship: participates_in CCO:I0019134 ! coil-csnk2b physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0011350 ! CSK2B_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0011351 ! CSK2B_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0011352 ! CSK2B_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0011353 ! CSK2B_HUMAN-Phosphoserine209 [Term] id: CCO:B0005898 name: BAT2_HUMAN def: "Large proline-rich protein BAT2" [UniProtKB:P48634] synonym: "HLA-B-associated transcript 2" EXACT [UniProtKB:P48634] xref: EMBL:AAA35585.1 xref: EMBL:AAA35586.1 xref: EMBL:AAD18086.1 xref: EMBL:AAH30127.1 xref: EMBL:AAH32134.1 xref: EMBL:AAH42295.1 xref: EMBL:AAH60668.1 xref: EMBL:BAB63391.1 xref: EMBL:BAE06116.1 xref: EMBL:CAA78744.1 xref: EMBL:CAH18101.1 xref: EMBL:CAI17698.2 xref: EMBL:CAI18313.1 xref: EMBL:CAI18499.1 xref: EMBL:CAI18500.1 xref: EMBL:CAI95572.1 xref: UniProtKB:O95875 xref: UniProtKB:P48634 xref: UniProtKB:Q05BK4 xref: UniProtKB:Q4LE37 xref: UniProtKB:Q5SQ29 xref: UniProtKB:Q5SQ30 xref: UniProtKB:Q5ST84 xref: UniProtKB:Q5STX6 xref: UniProtKB:Q5STX7 xref: UniProtKB:Q68DW9 xref: UniProtKB:Q6P9P7 xref: UniProtKB:Q6PIN1 xref: UniProtKB:Q8MGQ9 xref: UniProtKB:Q96QC6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004139 ! BAT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007337 ! bat2-mad2l2 physical interaction relationship: participates_in CCO:I0008772 ! bat2-psma3 physical interaction relationship: participates_in CCO:I0016179 ! atxn1-bat2 physical interaction relationship: participates_in CCO:I0018462 ! bat2-eif3s6 physical interaction relationship: participates_in CCO:I0018463 ! bat2-ddx20 physical interaction relationship: participates_in CCO:I0018464 ! bat2-fga physical interaction relationship: participates_in CCO:I0018465 ! bat2-hrmt1l1 physical interaction relationship: participates_in CCO:I0018466 ! bat2-gpr2 physical interaction relationship: participates_in CCO:I0018467 ! bat2-tg737 physical interaction relationship: participates_in CCO:I0018468 ! bat2-grb2 physical interaction relationship: participates_in CCO:I0018944 ! atxn1-bat2-1 physical interaction relationship: participates_in CCO:I0018990 ! atxn1-bat2-2 physical interaction relationship: participates_in CCO:I0019021 ! atxn1-bat2-3 physical interaction relationship: participates_in CCO:I0019162 ! rere-bat2 physical interaction relationship: transforms_into CCO:B0010729 ! BAT2_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0010730 ! BAT2_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0010731 ! BAT2_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0010732 ! BAT2_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0010733 ! BAT2_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0010734 ! BAT2_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0010735 ! BAT2_HUMAN-Phosphothreonine517 relationship: transforms_into CCO:B0010736 ! BAT2_HUMAN-Phosphothreonine610 relationship: transforms_into CCO:B0010737 ! BAT2_HUMAN-Phosphoserine759 relationship: transforms_into CCO:B0010738 ! BAT2_HUMAN-Phosphoserine761 relationship: transforms_into CCO:B0010739 ! BAT2_HUMAN-Phosphoserine764 relationship: transforms_into CCO:B0010740 ! BAT2_HUMAN-Phosphothreonine782 relationship: transforms_into CCO:B0010741 ! BAT2_HUMAN-Phosphoserine1004 relationship: transforms_into CCO:B0010742 ! BAT2_HUMAN-Phosphoserine1089 relationship: transforms_into CCO:B0010743 ! BAT2_HUMAN-Phosphoserine1092 relationship: transforms_into CCO:B0010744 ! BAT2_HUMAN-Phosphoserine1219 relationship: transforms_into CCO:B0010745 ! BAT2_HUMAN-Phosphothreonine1347 relationship: transforms_into CCO:B0010746 ! BAT2_HUMAN-Phosphothreonine1353 relationship: transforms_into CCO:B0026348 ! BAT2_HUMAN-Phosphoserine1014 relationship: transforms_into CCO:B0048176 ! BAT2_HUMAN-Phosphothreonine609 relationship: transforms_into CCO:B0063735 ! BAT2_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0063736 ! BAT2_HUMAN-Phosphoserine766 relationship: transforms_into CCO:B0063737 ! BAT2_HUMAN-Phosphothreonine997 relationship: transforms_into CCO:B0063738 ! BAT2_HUMAN-Phosphoserine1085 relationship: transforms_into CCO:B0063739 ! BAT2_HUMAN-Phosphothreonine1087 relationship: transforms_into CCO:B0063740 ! BAT2_HUMAN-Phosphotyrosine1094 relationship: transforms_into CCO:B0063741 ! BAT2_HUMAN-Phosphoserine1147 relationship: transforms_into CCO:B0063742 ! BAT2_HUMAN-Phosphoserine1306 [Term] id: CCO:B0005899 name: UAP56_HUMAN def: "Spliceosome RNA helicase BAT1" [UniProtKB:Q13838] synonym: "56 kDa U2AF65-associated protein" EXACT [UniProtKB:Q13838] synonym: "ATP-dependent RNA helicase p47" EXACT [UniProtKB:Q13838] synonym: "DEAD box protein UAP56" EXACT [UniProtKB:Q13838] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q13838] synonym: "HLA-B-associated transcript-1" EXACT [UniProtKB:Q13838] xref: EMBL:AAB94615.1 xref: EMBL:AAC63046.1 xref: EMBL:AAH00361.1 xref: EMBL:AAH13006.1 xref: EMBL:AAP88911.1 xref: EMBL:BAB63306.1 xref: EMBL:BAC54953.1 xref: EMBL:BAD96632.1 xref: EMBL:BAE78637.1 xref: EMBL:BAF31287.1 xref: EMBL:CAA85523.1 xref: EMBL:CAI17664.2 xref: EMBL:CAI17665.2 xref: EMBL:CAI18279.2 xref: EMBL:CAI18280.1 xref: EMBL:CAI18281.2 xref: EMBL:CAI18282.2 xref: EMBL:CAI18283.2 xref: EMBL:CAI18634.1 xref: EMBL:CAI41922.1 xref: EMBL:CAQ07176.1 xref: EMBL:CAQ09974.1 xref: EMBL:CAQ10634.1 xref: EMBL:EAX03404.1 xref: UniProtKB:B0S8C0 xref: UniProtKB:O43496 xref: UniProtKB:Q0EFA1 xref: UniProtKB:Q13838 xref: UniProtKB:Q2L6F9 xref: UniProtKB:Q53GL9 xref: UniProtKB:Q5RJ64 xref: UniProtKB:Q5RJ66 xref: UniProtKB:Q5ST94 xref: UniProtKB:Q5STB4 xref: UniProtKB:Q5STB5 xref: UniProtKB:Q5STB7 xref: UniProtKB:Q5STB8 xref: UniProtKB:Q5STU4 xref: UniProtKB:Q5STU5 xref: UniProtKB:Q5STU6 xref: UniProtKB:Q5STU8 xref: UniProtKB:Q71V76 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005852 ! BAT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007338 ! bat1-hipk2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008383 ! dnm2-bat1 physical interaction relationship: participates_in CCO:I0008980 ! bat1-rps15a physical interaction relationship: participates_in CCO:I0018470 ! bat1-hcc1 physical interaction relationship: participates_in CCO:I0018471 ! bat1-zhx1 physical interaction relationship: participates_in CCO:I0018472 ! bat1-piasx physical interaction relationship: participates_in CCO:I0018473 ! bat1-tdg physical interaction relationship: participates_in CCO:I0020462 ! strn4-bat1 physical interaction relationship: transforms_into CCO:B0071663 ! UAP56_HUMAN-Phosphothreonine172 [Term] id: CCO:B0005900 name: K2C8_HUMAN def: "Keratin, type II cytoskeletal 8" [UniProtKB:P05787] synonym: "CK-8" EXACT [UniProtKB:P05787] synonym: "Cytokeratin-8" EXACT [UniProtKB:P05787] synonym: "K8" EXACT [UniProtKB:P05787] synonym: "Keratin-8" EXACT [UniProtKB:P05787] xref: EMBL:AAA35748.1 xref: EMBL:AAA35763.1 xref: EMBL:AAA51542.1 xref: EMBL:AAB18966.1 xref: EMBL:AAH00654.3 xref: EMBL:AAH63513.2 xref: EMBL:AAH73760.1 xref: EMBL:AAH75839.1 xref: EMBL:BAD96661.1 xref: EMBL:CAA31376.1 xref: EMBL:CAA52882.1 xref: EMBL:CAA52916.1 xref: EMBL:CAA67203.1 xref: UniProtKB:P05787 xref: UniProtKB:Q14099 xref: UniProtKB:Q14716 xref: UniProtKB:Q14717 xref: UniProtKB:Q53GJ0 xref: UniProtKB:Q6DHW5 xref: UniProtKB:Q6GMY0 xref: UniProtKB:Q6P4C7 xref: UniProtKB:Q96J60 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004929 ! KRT8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007341 ! krt8-krt18 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0019999 ! fgfr3-krt8 physical interaction relationship: transforms_into CCO:B0012487 ! K2C8_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0012488 ! K2C8_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0012489 ! K2C8_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0012490 ! K2C8_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0012491 ! K2C8_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0012492 ! K2C8_HUMAN-Phosphothreonine26 relationship: transforms_into CCO:B0012493 ! K2C8_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0012494 ! K2C8_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0012495 ! K2C8_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0012496 ! K2C8_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0012497 ! K2C8_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0012498 ! K2C8_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0012499 ! K2C8_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0012500 ! K2C8_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0012501 ! K2C8_HUMAN-Phosphoserine417 relationship: transforms_into CCO:B0012502 ! K2C8_HUMAN-Phosphoserine424 relationship: transforms_into CCO:B0012503 ! K2C8_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0012504 ! K2C8_HUMAN-Phosphoserine451 relationship: transforms_into CCO:B0012505 ! K2C8_HUMAN-Phosphoserine475 relationship: transforms_into CCO:B0012506 ! K2C8_HUMAN-Phosphoserine478 relationship: transforms_into CCO:B0067248 ! K2C8_HUMAN-Phosphotyrosine204 relationship: transforms_into CCO:B0067249 ! K2C8_HUMAN-Phosphotyrosine267 [Term] id: CCO:B0005901 name: BCLX_HUMAN def: "Apoptosis regulator Bcl-X" [UniProtKB:Q07817] synonym: "Bcl-2-like 1 protein" EXACT [UniProtKB:Q07817] xref: EMBL:AAB17354.1 xref: EMBL:AAH19307.1 xref: EMBL:AAP35872.1 xref: EMBL:CAA80661.1 xref: EMBL:CAA80662.1 xref: EMBL:CAI12811.1 xref: EMBL:CAI23025.1 xref: UniProtKB:Q07817 xref: UniProtKB:Q5TE65 xref: UniProtKB:Q92976 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004155 ! BCL2L1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:I0007343 ! bcl_xl-bax physical interaction relationship: participates_in CCO:I0015827 ! bcl2l1-bik physical interaction relationship: participates_in CCO:I0015845 ! bak1-bcl2l1 physical interaction relationship: participates_in CCO:I0018205 ! bcl2l1-bcap31 physical interaction relationship: participates_in CCO:I0018615 ! bclxl-biml-1 physical interaction relationship: participates_in CCO:I0019465 ! bcl2l1-bik-1 direct interaction relationship: participates_in CCO:I0019466 ! bcl2l1-hrk direct interaction relationship: participates_in CCO:I0019467 ! bcl2l1-bbc3 direct interaction relationship: participates_in CCO:I0019468 ! bcl2l1-bid-1 direct interaction relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000841 ! negative regulation of survival gene product expression relationship: participates_in CCO:P0000844 ! apoptotic mitochondrial changes relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0005902 name: LEPR_HUMAN def: "Leptin receptor precursor" [UniProtKB:P48357] synonym: "CD295 antigen" EXACT [UniProtKB:P48357] synonym: "HuB219" EXACT [UniProtKB:P48357] synonym: "LEP-R" EXACT [UniProtKB:P48357] synonym: "OB receptor" EXACT [UniProtKB:P48357] synonym: "OB-R" EXACT [UniProtKB:P48357] xref: EMBL:AAA93015.1 xref: EMBL:AAB07495.1 xref: EMBL:AAB07496.1 xref: EMBL:AAB07497.1 xref: EMBL:AAB09673.1 xref: EMBL:AAC23650.1 xref: EMBL:AAC50509.1 xref: EMBL:AAC50510.1 xref: EMBL:AAC50511.1 xref: UniProtKB:P48357 xref: UniProtKB:Q13592 xref: UniProtKB:Q13593 xref: UniProtKB:Q13594 xref: UniProtKB:Q92919 xref: UniProtKB:Q92920 xref: UniProtKB:Q92921 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004976 ! LEPR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007345 ! lepr-jak2-1 physical interaction relationship: participates_in CCO:I0008259 ! lepr-pin1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0012696 ! LEPR_HUMAN-Phosphotyrosine986 relationship: transforms_into CCO:B0012697 ! LEPR_HUMAN-Phosphotyrosine1141 [Term] id: CCO:B0005903 name: CASP9_HUMAN def: "Caspase-9 precursor" [UniProtKB:P55211] synonym: "APAF-3" EXACT [UniProtKB:P55211] synonym: "Apoptotic protease Mch-6" EXACT [UniProtKB:P55211] synonym: "Apoptotic protease-activating factor 3" EXACT [UniProtKB:P55211] synonym: "CASP-9" EXACT [UniProtKB:P55211] synonym: "EC 3.4.22.62" EXACT [UniProtKB:P55211] synonym: "ICE-LAP6" EXACT [UniProtKB:P55211] synonym: "ICE-like apoptotic protease 6" EXACT [UniProtKB:P55211] xref: EMBL:AAC50640.1 xref: EMBL:AAC50776.1 xref: EMBL:AAD12248.1 xref: EMBL:AAD13615.1 xref: EMBL:AAH02452.1 xref: EMBL:AAH06463.1 xref: EMBL:AAO21133.1 xref: EMBL:BAA78780.1 xref: EMBL:BAA82697.1 xref: EMBL:BAA87905.1 xref: EMBL:CAC42423.1 xref: UniProtKB:O95348 xref: UniProtKB:P55211 xref: UniProtKB:Q92852 xref: UniProtKB:Q9BQ62 xref: UniProtKB:Q9UEQ3 xref: UniProtKB:Q9UIJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004222 ! CASP9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007348 ! birc5-casp9 physical interaction relationship: participates_in CCO:I0015839 ! birc4-casp9 physical interaction relationship: participates_in CCO:I0017696 ! apaf1-casp9-1 physical interaction relationship: participates_in CCO:I0017789 ! apaf1-casp9-5 direct interaction relationship: participates_in CCO:I0017871 ! casp9-apaf1-1 physical interaction relationship: participates_in CCO:I0017872 ! birc7-casp9-3 physical interaction relationship: participates_in CCO:I0017877 ! birc4-casp9-4 physical interaction relationship: participates_in CCO:I0017955 ! birc4-casp9-5 direct interaction relationship: participates_in CCO:I0018027 ! birc7-casp9-2 physical interaction relationship: participates_in CCO:I0018032 ! birc4-casp9-3 physical interaction relationship: participates_in CCO:I0018187 ! birc7-casp9-1 physical interaction relationship: participates_in CCO:I0018488 ! apaf1-casp9-4 physical interaction relationship: participates_in CCO:I0018491 ! birc7-casp9 physical interaction relationship: participates_in CCO:I0018616 ! apaf1-casp9-3 physical interaction relationship: participates_in CCO:I0019248 ! birc2-casp9-1 physical interaction relationship: participates_in CCO:I0019249 ! birc7-casp9-4 physical interaction relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0000842 ! caspase activation via cytochrome c relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0064080 ! CASP9_HUMAN-Phosphothreonine125 relationship: transforms_into CCO:B0064081 ! CASP9_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0064082 ! CASP9_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0064083 ! CASP9_HUMAN-Phosphoserine310 [Term] id: CCO:B0005904 name: DPOE2_HUMAN def: "DNA polymerase epsilon subunit 2" [UniProtKB:P56282] synonym: "DNA polymerase epsilon subunit B" EXACT [UniProtKB:P56282] synonym: "DNA polymerase II subunit 2" EXACT [UniProtKB:P56282] synonym: "EC 2.7.7.7" EXACT [UniProtKB:P56282] xref: EMBL:AAC39610.1 xref: EMBL:AAC51920.1 xref: EMBL:AAI26219.1 xref: EMBL:AAI26221.1 xref: EMBL:AAK72254.1 xref: EMBL:ABO43040.1 xref: UniProtKB:A0AV55 xref: UniProtKB:A4LBB7 xref: UniProtKB:A6NH58 xref: UniProtKB:O43560 xref: UniProtKB:P56282 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004506 ! POLE2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0007291 ! pole3-pole4-6 physical interaction relationship: participates_in CCO:I0007363 ! pole3-pole4-3 physical interaction relationship: participates_in CCO:I0007913 ! dpol-epsilon_human physical interaction relationship: participates_in CCO:I0018528 ! pole3-pole4-5 physical interaction relationship: participates_in CCO:I0019788 ! pole2-c14orf1 physical interaction relationship: participates_in CCO:I0019789 ! pole2-eef1a1 physical interaction relationship: participates_in CCO:I0019790 ! pole2-htatip physical interaction relationship: participates_in CCO:I0019791 ! pole2-tle1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0005905 name: DPOE4_HUMAN def: "DNA polymerase epsilon subunit 4" [UniProtKB:Q9NR33] synonym: "DNA polymerase epsilon subunit p12" EXACT [UniProtKB:Q9NR33] synonym: "DNA polymerase II subunit 4" EXACT [UniProtKB:Q9NR33] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9NR33] xref: EMBL:AAF90132.1 xref: EMBL:AAH31331.1 xref: EMBL:AAY15030.1 xref: UniProtKB:Q53TR2 xref: UniProtKB:Q9NR33 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004508 ! POLE4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007291 ! pole3-pole4-6 physical interaction relationship: participates_in CCO:I0007363 ! pole3-pole4-3 physical interaction relationship: participates_in CCO:I0007364 ! pole3-pole4-4 physical interaction relationship: participates_in CCO:I0007913 ! dpol-epsilon_human physical interaction relationship: participates_in CCO:I0018364 ! pole3-pole4-1 physical interaction relationship: participates_in CCO:I0018365 ! pole3-pole4-2 physical interaction relationship: participates_in CCO:I0018528 ! pole3-pole4-5 physical interaction relationship: transforms_into CCO:B0011579 ! DPOE4_HUMAN-Phosphoserine25 [Term] id: CCO:B0005906 name: ERBB4_HUMAN def: "Receptor tyrosine-protein kinase erbB-4 precursor" [UniProtKB:Q15303] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q15303] synonym: "p180erbB4" EXACT [UniProtKB:Q15303] synonym: "Tyrosine kinase-type cell surface receptor HER4" EXACT [UniProtKB:Q15303] xref: EMBL:AAB59446.1 xref: EMBL:AAI12200.1 xref: EMBL:BAD92934.1 xref: UniProtKB:Q15303 xref: UniProtKB:Q2M1W1 xref: UniProtKB:Q59EW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004579 ! ERBB4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: participates_in CCO:I0007366 ! erbb1-erbb4-2 physical interaction relationship: participates_in CCO:I0007593 ! erbb1-erbb4-1 physical interaction relationship: participates_in CCO:I0016316 ! erbb3-erbb4-2 physical interaction relationship: participates_in CCO:I0018249 ! erbb4-erbb2 physical interaction relationship: participates_in CCO:I0018311 ! erbb4-dlg4-5 physical interaction relationship: participates_in CCO:I0018355 ! erbb4-dlg4-3 physical interaction relationship: participates_in CCO:I0018397 ! erbb4-dlg4 physical interaction relationship: participates_in CCO:I0018398 ! erbb4-nmdar1 physical interaction relationship: participates_in CCO:I0018857 ! erbb4-dlg4-1 physical interaction relationship: participates_in CCO:I0018858 ! erbb4-sntb2-1 physical interaction relationship: participates_in CCO:I0018859 ! erbb4-dlg2-1 physical interaction relationship: participates_in CCO:I0018860 ! erbb4-dlg3-1 physical interaction relationship: participates_in CCO:I0018866 ! erbb3-erbb4-1 physical interaction relationship: participates_in CCO:I0018867 ! erbb4-erbb2-1 physical interaction relationship: participates_in CCO:I0019250 ! erbb4-dlg4-4 physical interaction relationship: participates_in CCO:I0019285 ! erbb4-dlg4-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0011741 ! ERBB4_HUMAN-Phosphotyrosine1162 relationship: transforms_into CCO:B0011742 ! ERBB4_HUMAN-Phosphotyrosine1188 relationship: transforms_into CCO:B0011743 ! ERBB4_HUMAN-Phosphotyrosine1258 relationship: transforms_into CCO:B0011744 ! ERBB4_HUMAN-Phosphotyrosine1284 relationship: transforms_into CCO:B0065104 ! ERBB4_HUMAN-Phosphotyrosine733 [Term] id: CCO:B0005907 name: P66A_HUMAN def: "Transcriptional repressor p66-alpha" [UniProtKB:Q86YP4] synonym: "GATA zinc finger domain-containing protein 2A" EXACT [UniProtKB:Q86YP4] synonym: "Hp66alpha" EXACT [UniProtKB:Q86YP4] xref: EMBL:AAH11684.1 xref: EMBL:AAH12902.2 xref: EMBL:AAO31797.1 xref: EMBL:BAA90939.1 xref: EMBL:CAB99095.1 xref: UniProtKB:Q7L3J2 xref: UniProtKB:Q86YP4 xref: UniProtKB:Q96F28 xref: UniProtKB:Q9NPU2 xref: UniProtKB:Q9NXS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005246 ! GATAD2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007368 ! pcaf-p66a physical interaction relationship: participates_in CCO:I0017738 ! mbd2-p66a physical interaction relationship: participates_in CCO:I0020616 ! pak4-p66alpha physical interaction relationship: participates_in CCO:P0000646 ! DNA methylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013351 ! P66A_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0013352 ! P66A_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0013353 ! P66A_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0013354 ! P66A_HUMAN-Phosphoserine546 relationship: transforms_into CCO:B0013355 ! P66A_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0048345 ! P66A_HUMAN-Phosphothreonine49 relationship: transforms_into CCO:B0048346 ! P66A_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0069026 ! P66A_HUMAN-Phosphoserine340 relationship: transforms_into CCO:B0069027 ! P66A_HUMAN-Phosphoserine548 [Term] id: CCO:B0005908 name: P66B_HUMAN def: "Transcriptional repressor p66-beta" [UniProtKB:Q8WXI9] synonym: "GATA zinc finger domain-containing protein 2B" EXACT [UniProtKB:Q8WXI9] synonym: "p66/p68" EXACT [UniProtKB:Q8WXI9] xref: EMBL:AAH69419.1 xref: EMBL:AAI12053.1 xref: EMBL:AAI12081.1 xref: EMBL:AAL39080.1 xref: EMBL:BAA86464.1 xref: EMBL:CAH71425.1 xref: UniProtKB:Q5VUR2 xref: UniProtKB:Q7LG68 xref: UniProtKB:Q8WXI9 xref: UniProtKB:Q9ULS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005247 ! GATAD2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007369 ! pcaf-p66b-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013356 ! P66B_HUMAN-Phosphothreonine120 relationship: transforms_into CCO:B0013357 ! P66B_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0013358 ! P66B_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0013359 ! P66B_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0013360 ! P66B_HUMAN-Phosphoserine486 relationship: transforms_into CCO:B0048347 ! P66B_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0048348 ! P66B_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0069028 ! P66B_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0069029 ! P66B_HUMAN-Phosphoserine333 [Term] id: CCO:B0005909 name: ADA15_HUMAN def: "ADAM 15 precursor" [UniProtKB:Q13444] synonym: "A disintegrin and metalloproteinase domain 15" EXACT [UniProtKB:Q13444] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q13444] synonym: "MDC-15" EXACT [UniProtKB:Q13444] synonym: "Metalloprotease RGD disintegrin protein" EXACT [UniProtKB:Q13444] synonym: "Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15" EXACT [UniProtKB:Q13444] synonym: "Metargidin" EXACT [UniProtKB:Q13444] xref: EMBL:AAC50404.1 xref: EMBL:AAC51112.1 xref: EMBL:AAH14566.1 xref: EMBL:AAM44189.1 xref: EMBL:AAP88766.1 xref: EMBL:AAS72992.1 xref: UniProtKB:Q13444 xref: UniProtKB:Q13493 xref: UniProtKB:Q53XQ0 xref: UniProtKB:Q96C78 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004026 ! ADAM15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007391 ! adam15-mad2l2-1 physical interaction relationship: participates_in CCO:I0017895 ! adam15-pacsin3-3 physical interaction relationship: participates_in CCO:I0018566 ! adam15-pacsin3-1 physical interaction relationship: participates_in CCO:I0018572 ! adam15-sh3gl2-1 physical interaction relationship: participates_in CCO:I0019438 ! adam15-sh3gl2-3 physical interaction relationship: transforms_into CCO:B0010451 ! ADA15_HUMAN-Phosphotyrosine715 relationship: transforms_into CCO:B0010452 ! ADA15_HUMAN-Phosphotyrosine735 [Term] id: CCO:B0005910 name: AKT2_HUMAN def: "RAC-beta serine/threonine-protein kinase" [UniProtKB:P31751] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P31751] synonym: "PKB beta" EXACT [UniProtKB:P31751] synonym: "Protein kinase Akt-2" EXACT [UniProtKB:P31751] synonym: "Protein kinase B, beta" EXACT [UniProtKB:P31751] synonym: "RAC-PK-beta" EXACT [UniProtKB:P31751] xref: EMBL:AAA36585.1 xref: EMBL:AAA58364.1 xref: EMBL:AAI20995.1 xref: EMBL:AAT97984.1 xref: UniProtKB:P31751 xref: UniProtKB:Q0VAN1 xref: UniProtKB:Q68GC0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004046 ! AKT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007398 ! cdc37-akt2 physical interaction relationship: participates_in CCO:I0017268 ! akt2-gsk3b-1 direct interaction relationship: participates_in CCO:I0017269 ! akt2-gsk3b-2 direct interaction relationship: transforms_into CCO:B0010493 ! AKT2_HUMAN-Phosphothreonine309 relationship: transforms_into CCO:B0010494 ! AKT2_HUMAN-Phosphoserine474 relationship: transforms_into CCO:B0065578 ! AKT2_HUMAN-Phosphoserine126 [Term] id: CCO:B0005911 name: AKT3_HUMAN def: "RAC-gamma serine/threonine-protein kinase" [UniProtKB:Q9Y243] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y243] synonym: "PKB gamma" EXACT [UniProtKB:Q9Y243] synonym: "Protein kinase Akt-3" EXACT [UniProtKB:Q9Y243] synonym: "Protein kinase B, gamma" EXACT [UniProtKB:Q9Y243] synonym: "RAC-PK-gamma" EXACT [UniProtKB:Q9Y243] synonym: "STK-2" EXACT [UniProtKB:Q9Y243] xref: EMBL:AAD24196.1 xref: EMBL:AAD29089.1 xref: EMBL:AAF91073.1 xref: EMBL:AAI21155.1 xref: EMBL:AAL40392.1 xref: EMBL:CAB53537.1 xref: EMBL:CAB55977.1 xref: EMBL:CAH71866.1 xref: EMBL:CAH71867.1 xref: EMBL:CAH72891.1 xref: EMBL:CAH72892.1 xref: EMBL:CAH73072.1 xref: EMBL:CAH73073.1 xref: EMBL:EAW77093.1 xref: EMBL:EAW77094.1 xref: UniProtKB:Q0VAA6 xref: UniProtKB:Q5VTI1 xref: UniProtKB:Q5VTI2 xref: UniProtKB:Q96QV3 xref: UniProtKB:Q9UFP5 xref: UniProtKB:Q9Y243 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004047 ! AKT3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007399 ! cdc37-akt3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010495 ! AKT3_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0010496 ! AKT3_HUMAN-Phosphoserine123 relationship: transforms_into CCO:B0010497 ! AKT3_HUMAN-Phosphothreonine305 relationship: transforms_into CCO:B0010498 ! AKT3_HUMAN-Phosphoserine472 [Term] id: CCO:B0005912 name: GNDS_HUMAN def: "Ral guanine nucleotide dissociation stimulator" [UniProtKB:Q12967] synonym: "RalGDS" EXACT [UniProtKB:Q12967] synonym: "RalGEF" EXACT [UniProtKB:Q12967] xref: EMBL:AAA52360.1 xref: EMBL:AAG02122.1 xref: EMBL:AAG10221.1 xref: EMBL:AAG10225.1 xref: EMBL:BAA92546.1 xref: UniProtKB:Q12967 xref: UniProtKB:Q9HAX7 xref: UniProtKB:Q9HAY1 xref: UniProtKB:Q9HCT1 xref: UniProtKB:Q9P2N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004711 ! RALGDS_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0018586 ! rit-af6 physical interaction relationship: participates_in CCO:I0018587 ! rit2-af6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0011953 ! GNDS_HUMAN-Phosphotyrosine586 [Term] id: CCO:B0005913 name: BRAF1_HUMAN def: "B-Raf proto-oncogene serine/threonine-protein kinase" [UniProtKB:P15056] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P15056] synonym: "p94" EXACT [UniProtKB:P15056] synonym: "v-Raf murine sarcoma viral oncogene homolog B1" EXACT [UniProtKB:P15056] xref: EMBL:AAA35609.2 xref: EMBL:AAA96495.1 xref: EMBL:AAD15551.1 xref: EMBL:AAD43193.1 xref: EMBL:AAI01758.1 xref: EMBL:AAI12080.1 xref: EMBL:CAA46301.1 xref: UniProtKB:P15056 xref: UniProtKB:Q13878 xref: UniProtKB:Q3MIN6 xref: UniProtKB:Q9UDP8 xref: UniProtKB:Q9Y6T3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004184 ! BRAF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0018500 ! braf-ywhab physical interaction relationship: participates_in CCO:I0018501 ! braf-oip5 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0010830 ! BRAF1_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0010831 ! BRAF1_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0010832 ! BRAF1_HUMAN-Phosphothreonine373 relationship: transforms_into CCO:B0010833 ! BRAF1_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0010834 ! BRAF1_HUMAN-Phosphoserine419 relationship: transforms_into CCO:B0010835 ! BRAF1_HUMAN-Phosphoserine446 relationship: transforms_into CCO:B0010836 ! BRAF1_HUMAN-Phosphoserine729 relationship: transforms_into CCO:B0010837 ! BRAF1_HUMAN-Phosphoserine750 relationship: transforms_into CCO:B0063980 ! BRAF1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0005914 name: AFAD_HUMAN def: "Afadin" [UniProtKB:P55196] synonym: "Protein AF-6" EXACT [UniProtKB:P55196] xref: EMBL:AAC50059.1 xref: EMBL:BAA32483.1 xref: EMBL:BAA32484.1 xref: EMBL:BAA32485.1 xref: EMBL:CAB82312.1 xref: EMBL:CAI20900.1 xref: EMBL:CAI40824.1 xref: EMBL:CAI42812.1 xref: UniProtKB:O75087 xref: UniProtKB:O75088 xref: UniProtKB:O75089 xref: UniProtKB:P55196 xref: UniProtKB:Q5TIG6 xref: UniProtKB:Q9NSN7 xref: UniProtKB:Q9NU92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004036 ! MLLT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007401 ! hras-ras physical interaction relationship: participates_in CCO:I0018586 ! rit-af6 physical interaction relationship: participates_in CCO:I0018587 ! rit2-af6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0010471 ! AFAD_HUMAN-Phosphoserine541 relationship: transforms_into CCO:B0010472 ! AFAD_HUMAN-Phosphoserine1090 relationship: transforms_into CCO:B0010473 ! AFAD_HUMAN-Phosphoserine1155 relationship: transforms_into CCO:B0010474 ! AFAD_HUMAN-Phosphoserine1156 relationship: transforms_into CCO:B0010475 ! AFAD_HUMAN-Phosphoserine1165 relationship: transforms_into CCO:B0010476 ! AFAD_HUMAN-Phosphoserine1184 relationship: transforms_into CCO:B0010477 ! AFAD_HUMAN-Phosphoserine1258 relationship: transforms_into CCO:B0010478 ! AFAD_HUMAN-Phosphothreonine1313 relationship: transforms_into CCO:B0010479 ! AFAD_HUMAN-Phosphothreonine1317 relationship: transforms_into CCO:B0010480 ! AFAD_HUMAN-Phosphoserine1681 relationship: transforms_into CCO:B0065465 ! AFAD_HUMAN-Phosphotyrosine94 relationship: transforms_into CCO:B0065466 ! AFAD_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0065467 ! AFAD_HUMAN-Phosphotyrosine1213 relationship: transforms_into CCO:B0065468 ! AFAD_HUMAN-Phosphothreonine1215 relationship: transforms_into CCO:B0065469 ! AFAD_HUMAN-Phosphoserine1679 relationship: transforms_into CCO:B0065470 ! AFAD_HUMAN-Phosphoserine1704 [Term] id: CCO:B0005915 name: M3K4_HUMAN def: "Mitogen-activated protein kinase kinase kinase 4" [UniProtKB:Q9Y6R4] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q9Y6R4] synonym: "MAP three kinase 1" EXACT [UniProtKB:Q9Y6R4] synonym: "MAPK/ERK kinase kinase 4" EXACT [UniProtKB:Q9Y6R4] synonym: "MEK kinase 4" EXACT [UniProtKB:Q9Y6R4] synonym: "MEKK 4" EXACT [UniProtKB:Q9Y6R4] xref: EMBL:AAB68804.1 xref: EMBL:BAA13204.2 xref: UniProtKB:Q92612 xref: UniProtKB:Q9Y6R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005008 ! MAP3K4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007408 ! map3k4-map2k61 physical interaction relationship: participates_in CCO:I0007530 ! map3k4-gadd45 physical interaction relationship: participates_in CCO:I0007531 ! map3k4-gadd45-2 physical interaction relationship: participates_in CCO:I0007532 ! map3k4-gadd45-3 physical interaction relationship: participates_in CCO:I0018599 ! map3k4-1 physical interaction relationship: participates_in CCO:P0000410 ! activation of MAPKK activity relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0012739 ! M3K4_HUMAN-Phosphoserine499 relationship: transforms_into CCO:B0012740 ! M3K4_HUMAN-Phosphothreonine1504 [Term] id: CCO:B0005916 name: EP400_HUMAN def: "E1A-binding protein p400" [UniProtKB:Q96L91] synonym: "CAG repeat protein 32" EXACT [UniProtKB:Q96L91] synonym: "Domino homolog" EXACT [UniProtKB:Q96L91] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q96L91] synonym: "hDomino" EXACT [UniProtKB:Q96L91] synonym: "p400 kDa SWI2/SNF2-related protein" EXACT [UniProtKB:Q96L91] synonym: "Trinucleotide repeat-containing gene 12 protein" EXACT [UniProtKB:Q96L91] xref: EMBL:AAB91441.1 xref: EMBL:AAH37208.1 xref: EMBL:AAH64554.1 xref: EMBL:AAK97789.1 xref: EMBL:BAA96022.1 xref: EMBL:BAB47447.1 xref: EMBL:BAC04759.1 xref: UniProtKB:O15411 xref: UniProtKB:Q6P2F5 xref: UniProtKB:Q8N8Q7 xref: UniProtKB:Q8NE05 xref: UniProtKB:Q96JK7 xref: UniProtKB:Q96L91 xref: UniProtKB:Q9P230 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004569 ! EP400_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0017346 ! c20orf20-epc1-5 physical interaction relationship: transforms_into CCO:B0011712 ! EP400_HUMAN-Phosphoserine736 relationship: transforms_into CCO:B0011713 ! EP400_HUMAN-Phosphoserine755 relationship: transforms_into CCO:B0011714 ! EP400_HUMAN-Phosphoserine1547 relationship: transforms_into CCO:B0065077 ! EP400_HUMAN-Phosphothreonine314 relationship: transforms_into CCO:B0065078 ! EP400_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0065079 ! EP400_HUMAN-Phosphothreonine320 relationship: transforms_into CCO:B0065080 ! EP400_HUMAN-Phosphoserine941 relationship: transforms_into CCO:B0065081 ! EP400_HUMAN-Phosphoserine943 relationship: transforms_into CCO:B0065082 ! EP400_HUMAN-Phosphothreonine945 relationship: transforms_into CCO:B0065083 ! EP400_HUMAN-Phosphoserine1728 relationship: transforms_into CCO:B0065084 ! EP400_HUMAN-Phosphoserine1732 relationship: transforms_into CCO:B0065085 ! EP400_HUMAN-Phosphothreonine2814 [Term] id: CCO:B0005917 name: MO4L1_HUMAN def: "Mortality factor 4-like protein 1" [UniProtKB:Q9UBU8] synonym: "MORF-related gene 15 protein" EXACT [UniProtKB:Q9UBU8] synonym: "MSL3-1 protein" EXACT [UniProtKB:Q9UBU8] synonym: "Transcription factor-like protein MRG15" EXACT [UniProtKB:Q9UBU8] xref: EMBL:AAD20058.1 xref: EMBL:AAD20970.1 xref: EMBL:AAD29872.1 xref: EMBL:AAF29033.1 xref: EMBL:AAF80854.1 xref: EMBL:AAG17253.1 xref: EMBL:AAH02936.1 xref: EMBL:AAH22845.1 xref: EMBL:AAH67826.1 xref: EMBL:AAN65338.1 xref: EMBL:AAQ13497.1 xref: EMBL:CAB70879.2 xref: UniProtKB:O95899 xref: UniProtKB:Q5QTS1 xref: UniProtKB:Q6NVX8 xref: UniProtKB:Q86YT7 xref: UniProtKB:Q9HBP6 xref: UniProtKB:Q9NSW5 xref: UniProtKB:Q9UBU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005108 ! MORF4L1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0007410 ! c20orf20-epc1-4 physical interaction relationship: participates_in CCO:I0015455 ! morf4l1-mrfap1l1 physical interaction relationship: participates_in CCO:I0017346 ! c20orf20-epc1-5 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0005918 name: TPD55_HUMAN def: "Tumor protein D55" [UniProtKB:Q96J77] synonym: "hD55" EXACT [UniProtKB:Q96J77] synonym: "Testis development protein NYD-SP25" EXACT [UniProtKB:Q96J77] synonym: "Tumor protein D52-like 3" EXACT [UniProtKB:Q96J77] xref: EMBL:AAH17589.1 xref: EMBL:AAH33792.1 xref: EMBL:AAH42113.1 xref: EMBL:AAK66820.1 xref: EMBL:BAB71505.1 xref: EMBL:CAI13289.1 xref: EMBL:CAI13290.1 xref: EMBL:CAI13291.1 xref: UniProtKB:Q5TCR3 xref: UniProtKB:Q5TCR4 xref: UniProtKB:Q5TCR5 xref: UniProtKB:Q8N4P5 xref: UniProtKB:Q8WWF7 xref: UniProtKB:Q96J77 xref: UniProtKB:Q96M09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005818 ! TPD52L3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007413 ! nyd_sp25-tpd53 physical interaction [Term] id: CCO:B0005919 name: RMI1_HUMAN def: "Protein RMI1 homolog" [UniProtKB:Q9H9A7] synonym: "75 kDa BLM-associated protein" EXACT [UniProtKB:Q9H9A7] synonym: "BLAP75" EXACT [UniProtKB:Q9H9A7] synonym: "FAAP75" EXACT [UniProtKB:Q9H9A7] xref: EMBL:AAH39999.1 xref: EMBL:AAH53549.1 xref: EMBL:AAH64937.1 xref: EMBL:BAB14325.1 xref: EMBL:CAI13575.1 xref: EMBL:CAI13576.1 xref: UniProtKB:Q5SQG8 xref: UniProtKB:Q5SQG9 xref: UniProtKB:Q6P1Q4 xref: UniProtKB:Q6PI89 xref: UniProtKB:Q7Z6L6 xref: UniProtKB:Q9H9A7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005516 ! RMI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007422 ! blm-c9orf76-2 physical interaction relationship: participates_in CCO:I0007427 ! c9orf76-blm-2 physical interaction relationship: participates_in CCO:I0007748 ! c9orf76-blm-1 physical interaction relationship: participates_in CCO:I0007749 ! blm-c9orf76-1 physical interaction relationship: participates_in CCO:I0008561 ! c9orf76-blm-4 colocalization relationship: participates_in CCO:I0008565 ! c9orf76-blm-3 physical interaction relationship: transforms_into CCO:B0013907 ! RMI1_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0070094 ! RMI1_HUMAN-Phosphoserine225 [Term] id: CCO:B0005920 name: FGFR3_HUMAN def: "Fibroblast growth factor receptor 3 precursor" [UniProtKB:P22607] synonym: "CD333 antigen" EXACT [UniProtKB:P22607] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P22607] synonym: "FGFR-3" EXACT [UniProtKB:P22607] xref: EMBL:AAA52450.1 xref: EMBL:AAA58470.1 xref: EMBL:AAA63209.1 xref: EMBL:AAA67781.1 xref: EMBL:AAB33323.1 xref: EMBL:AAF63380.1 xref: EMBL:AAU89726.1 xref: EMBL:CAA59334.1 xref: UniProtKB:P22607 xref: UniProtKB:Q14308 xref: UniProtKB:Q16294 xref: UniProtKB:Q16608 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004644 ! FGFR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007432 ! fgf-fgfr-2 direct interaction relationship: participates_in CCO:I0007433 ! fgf-fgfr-3 direct interaction relationship: participates_in CCO:I0007435 ! fgf-fgfr-1 direct interaction relationship: participates_in CCO:I0008232 ! fgfr3-centd2 physical interaction relationship: participates_in CCO:I0008387 ! fgfr3-flj22624 physical interaction relationship: participates_in CCO:I0018461 ! g18_1b-fgfr3 physical interaction relationship: participates_in CCO:I0018665 ! fgf-fgfr-4 direct interaction relationship: participates_in CCO:I0019716 ! fgfr3-kiaa1377 physical interaction relationship: participates_in CCO:I0019717 ! fgfr3-rpl8 physical interaction relationship: participates_in CCO:I0019718 ! fgfr3-slc25a6 physical interaction relationship: participates_in CCO:I0019994 ! fgfr3-atf3 physical interaction relationship: participates_in CCO:I0019995 ! fgfr3-chgb physical interaction relationship: participates_in CCO:I0019996 ! fgfr3-ctsk physical interaction relationship: participates_in CCO:I0019997 ! fgfr3-flj10324 physical interaction relationship: participates_in CCO:I0019998 ! fgfr3-gtf3c1 physical interaction relationship: participates_in CCO:I0019999 ! fgfr3-krt8 physical interaction relationship: participates_in CCO:I0020000 ! fgfr3-pola2 physical interaction relationship: participates_in CCO:I0020001 ! fgfr3-sma3 physical interaction relationship: participates_in CCO:I0020310 ! fgfr3-c1orf16 physical interaction relationship: participates_in CCO:I0020311 ! fgfr3-q96lx7 physical interaction relationship: participates_in CCO:I0020312 ! fgfr3-hbz physical interaction relationship: participates_in CCO:I0020313 ! fgfr3-hnrpl physical interaction relationship: participates_in CCO:I0020314 ! fgfr3-ndufs6 physical interaction relationship: participates_in CCO:I0020315 ! fgfr3-rnf130 physical interaction relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: transforms_into CCO:B0011880 ! FGFR3_HUMAN-Phosphotyrosine648 relationship: transforms_into CCO:B0031317 ! FGFR3_HUMAN-Phosphotyrosine647 [Term] id: CCO:B0005921 name: IGHA1_HUMAN def: "Ig alpha-1 chain C region" [UniProtKB:P01876] xref: EMBL:AAC82528.1 xref: UniProtKB:P01876 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004869 ! IGHA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007447 ! apc-ctbb1 physical interaction [Term] id: CCO:B0005922 name: K1C9_HUMAN def: "Keratin, type I cytoskeletal 9" [UniProtKB:P35527] synonym: "CK-9" EXACT [UniProtKB:P35527] synonym: "Cytokeratin-9" EXACT [UniProtKB:P35527] synonym: "K9" EXACT [UniProtKB:P35527] synonym: "Keratin-9" EXACT [UniProtKB:P35527] xref: EMBL:AAC60619.1 xref: EMBL:AAI21171.1 xref: EMBL:BAA19418.1 xref: EMBL:CAA52924.1 xref: EMBL:CAA82315.1 xref: UniProtKB:O00109 xref: UniProtKB:P35527 xref: UniProtKB:Q0IJ47 xref: UniProtKB:Q14665 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004924 ! KRT9_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: participates_in CCO:I0007447 ! apc-ctbb1 physical interaction relationship: participates_in CCO:I0016577 ! tank-krt9 physical interaction relationship: participates_in CCO:I0020355 ! krt9-sh3gl3 physical interaction [Term] id: CCO:B0005923 name: BMX_HUMAN def: "Cytoplasmic tyrosine-protein kinase BMX" [UniProtKB:P51813] synonym: "Bone marrow tyrosine kinase gene in chromosome X protein" EXACT [UniProtKB:P51813] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P51813] synonym: "Epithelial and endothelial tyrosine kinase" EXACT [UniProtKB:P51813] synonym: "ETK" EXACT [UniProtKB:P51813] synonym: "NTK38" EXACT [UniProtKB:P51813] xref: EMBL:AAA17744.1 xref: EMBL:AAC08966.1 xref: EMBL:AAH16652.1 xref: EMBL:CAA58169.1 xref: EMBL:EAW98889.1 xref: UniProtKB:A6NIH9 xref: UniProtKB:O60564 xref: UniProtKB:P51813 xref: UniProtKB:Q12871 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004175 ! BMX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007449 ! bmx-tp53-1 physical interaction relationship: participates_in CCO:I0017765 ! pim1-bmx-5 physical interaction relationship: participates_in CCO:I0018344 ! pim1-bmx-4 physical interaction relationship: participates_in CCO:I0018345 ! pim1-bmx-7 physical interaction relationship: participates_in CCO:I0018675 ! pim1-bmx-6 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0010815 ! BMX_HUMAN-Phosphotyrosine566 relationship: transforms_into CCO:B0048178 ! BMX_HUMAN-Phosphotyrosine216 relationship: transforms_into CCO:B0048179 ! BMX_HUMAN-Phosphotyrosine224 [Term] id: CCO:B0005924 name: GAB2_HUMAN def: "GRB2-associated-binding protein 2" [UniProtKB:Q9UQC2] synonym: "GRB2-associated binder 2" EXACT [UniProtKB:Q9UQC2] synonym: "Growth factor receptor bound protein 2-associated protein 2" EXACT [UniProtKB:Q9UQC2] synonym: "pp100" EXACT [UniProtKB:Q9UQC2] xref: EMBL:BAA25497.2 xref: EMBL:BAA76737.1 xref: UniProtKB:O60317 xref: UniProtKB:Q9UQC2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004677 ! GAB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007453 ! gab2-grb2-1 physical interaction relationship: transforms_into CCO:B0011917 ! GAB2_HUMAN-Phosphotyrosine266 relationship: transforms_into CCO:B0011918 ! GAB2_HUMAN-Phosphoserine405 relationship: transforms_into CCO:B0031324 ! GAB2_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0031325 ! GAB2_HUMAN-Phosphothreonine265 relationship: transforms_into CCO:B0031326 ! GAB2_HUMAN-Phosphotyrosine293 relationship: transforms_into CCO:B0066361 ! GAB2_HUMAN-Phosphoserine543 [Term] id: CCO:B0005925 name: SMCA2_HUMAN def: "Probable global transcription activator SNF2L2" [UniProtKB:P51531] synonym: "ATP-dependent helicase SMARCA2" EXACT [UniProtKB:P51531] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P51531] synonym: "hBRM" EXACT [UniProtKB:P51531] synonym: "SNF2-alpha" EXACT [UniProtKB:P51531] synonym: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2" EXACT [UniProtKB:P51531] xref: EMBL:BAA05142.1 xref: EMBL:CAA51407.1 xref: EMBL:CAI12967.1 xref: EMBL:CAI12968.1 xref: EMBL:CAI14599.1 xref: EMBL:CAI14600.1 xref: EMBL:EAW58811.1 xref: EMBL:EAW58813.1 xref: UniProtKB:B1ALG3 xref: UniProtKB:B1ALG4 xref: UniProtKB:P51531 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005630 ! SMARCA2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007477 ! smarca2-sam68 physical interaction relationship: participates_in CCO:I0007512 ! smarca2-sam68-1 physical interaction relationship: participates_in CCO:I0015881 ! brm-mecp2-4 physical interaction relationship: participates_in CCO:I0015882 ! brm-mecp2-5 physical interaction relationship: participates_in CCO:I0017487 ! act16b-smarca2-1 physical interaction relationship: participates_in CCO:I0017490 ! brm-mecp2-2 physical interaction relationship: participates_in CCO:I0017491 ! brm-mecp2-3 physical interaction relationship: participates_in CCO:I0017883 ! arid1a--smarca2-1 physical interaction relationship: participates_in CCO:I0017886 ! arid1b-smarca2-2 physical interaction relationship: participates_in CCO:I0018068 ! smarca2-arid1a-1 physical interaction relationship: participates_in CCO:I0018069 ! smarca2-arid1b-1 physical interaction relationship: participates_in CCO:I0018326 ! arid1b-smarca2-3 physical interaction relationship: participates_in CCO:I0018328 ! arid1a--smarca2-2 physical interaction relationship: participates_in CCO:I0018721 ! smarca2-c20orf14 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0014095 ! SMCA2_HUMAN-N6-acetyllysine1551 relationship: transforms_into CCO:B0014097 ! SMCA2_HUMAN-Phosphoserine1568 relationship: transforms_into CCO:B0070620 ! SMCA2_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0070621 ! SMCA2_HUMAN-Phosphoserine591 relationship: transforms_into CCO:B0070622 ! SMCA2_HUMAN-Phosphoserine956 relationship: transforms_into CCO:B0070623 ! SMCA2_HUMAN-Phosphoserine1377 relationship: transforms_into CCO:B0070624 ! SMCA2_HUMAN-Phosphoserine1410 relationship: transforms_into CCO:B0070625 ! SMCA2_HUMAN-Phosphoserine1418 relationship: transforms_into CCO:B0070626 ! SMCA2_HUMAN-Phosphoserine1419 relationship: transforms_into CCO:B0070627 ! SMCA2_HUMAN-N6-acetyllysine1553 relationship: transforms_into CCO:B0070628 ! SMCA2_HUMAN-N6-acetyllysine1555 relationship: transforms_into CCO:B0070629 ! SMCA2_HUMAN-Phosphoserine1572 [Term] id: CCO:B0005926 name: NDEL1_HUMAN def: "Nuclear distribution protein nudE-like 1" [UniProtKB:Q9GZM8] synonym: "Mitosin-associated protein 1" EXACT [UniProtKB:Q9GZM8] synonym: "Protein Nudel" EXACT [UniProtKB:Q9GZM8] xref: EMBL:AAF24516.3 xref: EMBL:AAF97497.1 xref: EMBL:AAG43425.1 xref: EMBL:AAH26101.1 xref: EMBL:CAD89957.3 xref: UniProtKB:Q86T80 xref: UniProtKB:Q8TAR7 xref: UniProtKB:Q9GZM8 xref: UniProtKB:Q9UH50 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005164 ! NDEL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007489 ! ndel1_pafah1b1_1 physical interaction relationship: participates_in CCO:I0007490 ! pafah1b1_ndel1_1 physical interaction relationship: participates_in CCO:I0017434 ! mitap1-hapip physical interaction relationship: participates_in CCO:I0017451 ! mitap1-snx6 physical interaction relationship: participates_in CCO:I0017478 ! mitap1-znf10 physical interaction relationship: participates_in CCO:I0017479 ! mitap1-znf17 physical interaction relationship: participates_in CCO:I0017481 ! mitap1-znf197 physical interaction relationship: participates_in CCO:I0017482 ! mitap1-znf211 physical interaction relationship: participates_in CCO:I0017483 ! mitap1-znf230 physical interaction relationship: participates_in CCO:I0017485 ! mitap1-znf91 physical interaction relationship: transforms_into CCO:B0013135 ! NDEL1_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0013136 ! NDEL1_HUMAN-Phosphothreonine219 relationship: transforms_into CCO:B0013137 ! NDEL1_HUMAN-Phosphoserine242 relationship: transforms_into CCO:B0013138 ! NDEL1_HUMAN-Phosphothreonine245 [Term] id: CCO:B0005927 name: H33_HUMAN def: "Histone H3.3" [UniProtKB:P84243] xref: EMBL:AAA52653.1 xref: EMBL:AAA52654.1 xref: EMBL:AAG17271.1 xref: EMBL:AAH01124.1 xref: EMBL:AAH06497.1 xref: EMBL:AAH12813.1 xref: EMBL:AAH17558.1 xref: EMBL:AAH29405.1 xref: EMBL:AAH38989.1 xref: EMBL:AAH66901.1 xref: EMBL:AAH67757.1 xref: EMBL:AAH81560.1 xref: EMBL:AAH81561.1 xref: EMBL:AAH95447.1 xref: EMBL:AAI08702.1 xref: EMBL:CAA29288.1 xref: EMBL:CAA88778.1 xref: EMBL:CAD97621.1 xref: EMBL:CAH73371.1 xref: EMBL:CAH73372.1 xref: UniProtKB:P06351 xref: UniProtKB:P33155 xref: UniProtKB:P84243 xref: UniProtKB:Q5VV55 xref: UniProtKB:Q5VV56 xref: UniProtKB:Q66I33 xref: UniProtKB:Q9V3W4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004761 ! H3F3A_human relationship: encoded_by CCO:G0004762 ! H3F3B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007514 ! h3_peptide-cul4a physical interaction relationship: transforms_into CCO:B0012096 ! H33_HUMAN-Phosphothreonine4 relationship: transforms_into CCO:B0012097 ! H33_HUMAN-N6-acetyllysine5 relationship: transforms_into CCO:B0012098 ! H33_HUMAN-N6-methyllysine5 relationship: transforms_into CCO:B0012099 ! H33_HUMAN-Citrulline9 relationship: transforms_into CCO:B0012100 ! H33_HUMAN-dimethylarginine9 relationship: transforms_into CCO:B0012101 ! H33_HUMAN-N6,N6,N6-trimethyllysine10 relationship: transforms_into CCO:B0012102 ! H33_HUMAN-N6,N6-dimethyllysine10 relationship: transforms_into CCO:B0012103 ! H33_HUMAN-N6-acetyllysine10 relationship: transforms_into CCO:B0012104 ! H33_HUMAN-N6-methyllysine10 relationship: transforms_into CCO:B0012105 ! H33_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0012106 ! H33_HUMAN-Phosphothreonine12 relationship: transforms_into CCO:B0012107 ! H33_HUMAN-N6-acetyllysine15 relationship: transforms_into CCO:B0012108 ! H33_HUMAN-dimethylarginine18 relationship: transforms_into CCO:B0012109 ! H33_HUMAN-Citrulline18 relationship: transforms_into CCO:B0012110 ! H33_HUMAN-N6-acetyllysine19 relationship: transforms_into CCO:B0012111 ! H33_HUMAN-N6-methyllysine19 relationship: transforms_into CCO:B0012112 ! H33_HUMAN-N6-acetyllysine24 relationship: transforms_into CCO:B0012113 ! H33_HUMAN-N6-methyllysine24 relationship: transforms_into CCO:B0012114 ! H33_HUMAN-N6,N6,N6-trimethyllysine28 relationship: transforms_into CCO:B0012115 ! H33_HUMAN-N6,N6-dimethyllysine28 relationship: transforms_into CCO:B0012116 ! H33_HUMAN-N6-acetyllysine28 relationship: transforms_into CCO:B0012117 ! H33_HUMAN-N6-methyllysine28 relationship: transforms_into CCO:B0012118 ! H33_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0012119 ! H33_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0012120 ! H33_HUMAN-N6,N6,N6-trimethyllysine37 relationship: transforms_into CCO:B0012121 ! H33_HUMAN-N6,N6-dimethyllysine37 relationship: transforms_into CCO:B0012122 ! H33_HUMAN-N6-acetyllysine37 relationship: transforms_into CCO:B0012123 ! H33_HUMAN-N6-methyllysine37 relationship: transforms_into CCO:B0012124 ! H33_HUMAN-N6,N6,N6-trimethyllysine57 relationship: transforms_into CCO:B0012125 ! H33_HUMAN-N6-acetyllysine57 relationship: transforms_into CCO:B0012126 ! H33_HUMAN-N6-methyllysine57 relationship: transforms_into CCO:B0012127 ! H33_HUMAN-N6-methyllysine65 relationship: transforms_into CCO:B0012128 ! H33_HUMAN-N6,N6,N6-trimethyllysine80 relationship: transforms_into CCO:B0012129 ! H33_HUMAN-N6,N6-dimethyllysine80 relationship: transforms_into CCO:B0012130 ! H33_HUMAN-N6-acetyllysine80 relationship: transforms_into CCO:B0012131 ! H33_HUMAN-N6-methyllysine80 relationship: transforms_into CCO:B0012132 ! H33_HUMAN-N6-methyllysine123 [Term] id: CCO:B0005928 name: VRK2_HUMAN def: "Serine/threonine-protein kinase VRK2" [UniProtKB:Q86Y07] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q86Y07] synonym: "Vaccinia-related kinase 2" EXACT [UniProtKB:Q86Y07] xref: EMBL:AAH27854.1 xref: EMBL:AAH36434.1 xref: EMBL:AAO73047.1 xref: EMBL:AAO73048.1 xref: EMBL:AAO73049.1 xref: EMBL:AAO73050.1 xref: EMBL:AAO73051.1 xref: EMBL:AAO73052.1 xref: EMBL:BAA19109.1 xref: EMBL:BAD97260.1 xref: EMBL:CAD54446.2 xref: UniProtKB:Q49AK9 xref: UniProtKB:Q53EU9 xref: UniProtKB:Q86Y07 xref: UniProtKB:Q86Y08 xref: UniProtKB:Q86Y09 xref: UniProtKB:Q86Y10 xref: UniProtKB:Q86Y11 xref: UniProtKB:Q86Y12 xref: UniProtKB:Q8IXI5 xref: UniProtKB:Q99987 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005907 ! VRK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007518 ! bcl2-vrk2 physical interaction [Term] id: CCO:B0005929 name: HMGB1_HUMAN def: "High mobility group protein B1" [UniProtKB:P09429] synonym: "High mobility group protein 1" EXACT [UniProtKB:P09429] synonym: "HMG-1" EXACT [UniProtKB:P09429] xref: EMBL:AAB08987.1 xref: EMBL:AAH03378.1 xref: EMBL:AAH30981.1 xref: EMBL:AAH66889.1 xref: EMBL:AAH67732.1 xref: EMBL:AAI41845.1 xref: EMBL:AAP35586.1 xref: EMBL:AAQ91389.1 xref: EMBL:AAV38961.1 xref: EMBL:ABM47301.1 xref: EMBL:ABS29271.1 xref: EMBL:BAA09924.1 xref: EMBL:BAF84183.1 xref: EMBL:BAG53745.1 xref: EMBL:CAA31110.1 xref: EMBL:CAG33144.1 xref: EMBL:CAH18408.1 xref: EMBL:CAI15600.1 xref: EMBL:EAX08457.1 xref: UniProtKB:A5D8W9 xref: UniProtKB:P09429 xref: UniProtKB:Q14321 xref: UniProtKB:Q5T7C3 xref: UniProtKB:Q6IBE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004812 ! HMGB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007526 ! hmgb1-tp73-1 physical interaction relationship: participates_in CCO:I0007949 ! tp53-hmgb1 physical interaction relationship: participates_in CCO:I0008119 ! hmgb1-rif1 physical interaction relationship: participates_in CCO:I0018142 ! hmgb1-tbp-1 physical interaction relationship: participates_in CCO:I0019733 ! hmgb1-unc119 physical interaction relationship: participates_in CCO:I0020025 ! hmgb1-c14orf1 physical interaction relationship: participates_in CCO:I0020026 ! hmgb1-crmp1 physical interaction relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001133 ! negative regulation of transcriptional preinitiation complex assembly relationship: transforms_into CCO:B0012197 ! HMGB1_HUMAN-N6-acetyllysine30 relationship: transforms_into CCO:B0012198 ! HMGB1_HUMAN-Phosphoserine35 [Term] id: CCO:B0005930 name: GGA3_HUMAN def: "ADP-ribosylation factor-binding protein GGA3" [UniProtKB:Q9NZ52] synonym: "Golgi-localized, gamma ear-containing, ARF-binding protein 3" EXACT [UniProtKB:Q9NZ52] xref: EMBL:AAF05709.1 xref: EMBL:AAF42848.1 xref: EMBL:AAF42849.1 xref: EMBL:AAH70044.1 xref: EMBL:BAA09926.1 xref: UniProtKB:Q15017 xref: UniProtKB:Q6IS16 xref: UniProtKB:Q9NZ52 xref: UniProtKB:Q9UJY3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004698 ! GGA3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004389 ! ADP-ribosylation factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: participates_in CCO:I0019488 ! gga3-tsg101-1 physical interaction [Term] id: CCO:B0005931 name: IMA3_HUMAN def: "Importin subunit alpha-3" [UniProtKB:O00505] synonym: "Importin alpha Q2" EXACT [UniProtKB:O00505] synonym: "Karyopherin subunit alpha-3" EXACT [UniProtKB:O00505] synonym: "Qip2" EXACT [UniProtKB:O00505] synonym: "SRP1-gamma" EXACT [UniProtKB:O00505] xref: EMBL:AAB87693.1 xref: EMBL:AAH17355.1 xref: EMBL:AAH24202.1 xref: EMBL:BAA20378.1 xref: EMBL:CAA73026.1 xref: UniProtKB:O00191 xref: UniProtKB:O00505 xref: UniProtKB:O43195 xref: UniProtKB:Q96AA7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004887 ! KPNA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007556 ! cdn1b-kpna3-1 physical interaction relationship: participates_in CCO:I0007557 ! cdn1b-kpna3-2 physical interaction relationship: participates_in CCO:I0007861 ! cdn1b-kpna3-3 physical interaction relationship: participates_in CCO:I0007862 ! cdn1b-kpna5-5 physical interaction relationship: transforms_into CCO:B0012378 ! IMA3_HUMAN-Phosphoserine60 [Term] id: CCO:B0005932 name: UBL5_HUMAN def: "Ubiquitin-like protein 5" [UniProtKB:Q9BZL1] xref: EMBL:AAH07053.1 xref: EMBL:AAI10840.1 xref: EMBL:AAK14178.1 xref: EMBL:AAP36019.1 xref: UniProtKB:Q2NL89 xref: UniProtKB:Q9BZL1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005867 ! UBL5_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007564 ! ubl5-sart1-1 physical interaction [Term] id: CCO:B0005933 name: BTBD2_HUMAN def: "BTB/POZ domain-containing protein 2" [UniProtKB:Q9BX70] xref: EMBL:AAC16070.1 xref: EMBL:AAC26984.1 xref: EMBL:AAG45443.1 xref: EMBL:AAH00564.2 xref: EMBL:AAH08035.2 xref: EMBL:AAH53986.1 xref: EMBL:AAH94820.1 xref: EMBL:AAK25826.1 xref: EMBL:BAA91136.1 xref: EMBL:BAB55143.1 xref: EMBL:CAB96527.1 xref: EMBL:CAG33511.1 xref: UniProtKB:O60418 xref: UniProtKB:O75248 xref: UniProtKB:Q4VBZ1 xref: UniProtKB:Q6IAC5 xref: UniProtKB:Q7Z5W0 xref: UniProtKB:Q96SX8 xref: UniProtKB:Q9BX70 xref: UniProtKB:Q9NPS1 xref: UniProtKB:Q9NX81 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004193 ! BTBD2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007577 ! tp53-btbd2-1 physical interaction relationship: participates_in CCO:I0007999 ! btbd2-tp53 physical interaction relationship: participates_in CCO:I0008204 ! btbd2-ptn physical interaction relationship: participates_in CCO:I0019570 ! btbd2-tle1 physical interaction relationship: participates_in CCO:I0019671 ! btbd2-setdb1 physical interaction relationship: participates_in CCO:I0019928 ! btbd2-gdf9 physical interaction [Term] id: CCO:B0005934 name: WNK4_HUMAN def: "Serine/threonine-protein kinase WNK4" [UniProtKB:Q96J92] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q96J92] synonym: "Protein kinase with no lysine 4" EXACT [UniProtKB:Q96J92] synonym: "Protein kinase, lysine-deficient 4" EXACT [UniProtKB:Q96J92] xref: EMBL:AAK91995.1 xref: EMBL:BAC04669.1 xref: EMBL:BAC04688.1 xref: EMBL:CAC32991.1 xref: EMBL:CAC48387.1 xref: UniProtKB:Q8N8X3 xref: UniProtKB:Q8N8Z2 xref: UniProtKB:Q96DT8 xref: UniProtKB:Q96J92 xref: UniProtKB:Q9BYS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005931 ! WNK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0007582 ! bcl6-hdac4 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002955 ! regulation of cellular process relationship: transforms_into CCO:B0014695 ! WNK4_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0014696 ! WNK4_HUMAN-Phosphoserine335 [Term] id: CCO:B0005935 name: PKCB1_HUMAN def: "Protein kinase C-binding protein 1" [UniProtKB:Q9ULU4] synonym: "CTCL tumor antigen se14-3" EXACT [UniProtKB:Q9ULU4] synonym: "Cutaneous T-cell lymphoma-associated antigen se14-3" EXACT [UniProtKB:Q9ULU4] synonym: "Rack7" EXACT [UniProtKB:Q9ULU4] synonym: "Zinc finger MYND domain-containing protein 8" EXACT [UniProtKB:Q9ULU4] xref: EMBL:AAC72244.1 xref: EMBL:AAF71262.1 xref: EMBL:AAG34905.1 xref: EMBL:AAH30721.2 xref: EMBL:AAL50790.1 xref: EMBL:AAY85630.1 xref: EMBL:AAY85631.1 xref: EMBL:BAA86439.1 xref: EMBL:CAE46008.1 xref: EMBL:CAI20089.1 xref: EMBL:CAI21842.1 xref: EMBL:CAI23169.1 xref: UniProtKB:Q13517 xref: UniProtKB:Q4JJ94 xref: UniProtKB:Q4JJ95 xref: UniProtKB:Q5TH09 xref: UniProtKB:Q6MZM1 xref: UniProtKB:Q8WXC5 xref: UniProtKB:Q9H1F3 xref: UniProtKB:Q9H1F4 xref: UniProtKB:Q9H1F5 xref: UniProtKB:Q9H1L8 xref: UniProtKB:Q9H1L9 xref: UniProtKB:Q9H2G5 xref: UniProtKB:Q9NYN3 xref: UniProtKB:Q9UIX6 xref: UniProtKB:Q9ULU4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005323 ! ZMYND8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007582 ! bcl6-hdac4 physical interaction relationship: participates_in CCO:I0007584 ! pkc-bcl6 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0019160 ! rere-prkcbp1 physical interaction relationship: transforms_into CCO:B0013534 ! PKCB1_HUMAN-Phosphoserine486 relationship: transforms_into CCO:B0013535 ! PKCB1_HUMAN-Phosphoserine490 relationship: transforms_into CCO:B0013536 ! PKCB1_HUMAN-Phosphoserine547 relationship: transforms_into CCO:B0013537 ! PKCB1_HUMAN-Phosphoserine652 relationship: transforms_into CCO:B0013538 ! PKCB1_HUMAN-Phosphoserine668 relationship: transforms_into CCO:B0013539 ! PKCB1_HUMAN-Phosphoserine1086 relationship: transforms_into CCO:B0069321 ! PKCB1_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0069322 ! PKCB1_HUMAN-Phosphoserine460 relationship: transforms_into CCO:B0069323 ! PKCB1_HUMAN-Phosphoserine462 relationship: transforms_into CCO:B0069324 ! PKCB1_HUMAN-Phosphoserine465 relationship: transforms_into CCO:B0069325 ! PKCB1_HUMAN-Phosphoserine488 relationship: transforms_into CCO:B0069326 ! PKCB1_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0069327 ! PKCB1_HUMAN-Phosphothreonine541 relationship: transforms_into CCO:B0069328 ! PKCB1_HUMAN-Phosphoserine756 [Term] id: CCO:B0005936 name: FANCF_HUMAN def: "Fanconi anemia group F protein" [UniProtKB:Q9NPI8] synonym: "Protein FACF" EXACT [UniProtKB:Q9NPI8] xref: EMBL:AAF26297.1 xref: EMBL:AAF26298.1 xref: EMBL:AAH47028.1 xref: EMBL:AAH93867.1 xref: EMBL:AAI01808.1 xref: EMBL:AAX09677.1 xref: EMBL:BAB14433.1 xref: UniProtKB:Q52LM0 xref: UniProtKB:Q9NPI8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004610 ! FANCF_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007587 ! fancg-fancf-1 physical interaction [Term] id: CCO:B0005937 name: TAF10_HUMAN def: "Transcription initiation factor TFIID subunit 10" [UniProtKB:Q12962] synonym: "STAF28" EXACT [UniProtKB:Q12962] synonym: "TAF(II)30" EXACT [UniProtKB:Q12962] synonym: "TAFII-30" EXACT [UniProtKB:Q12962] synonym: "TAFII30" EXACT [UniProtKB:Q12962] synonym: "Transcription initiation factor TFIID 30 kDa subunit" EXACT [UniProtKB:Q12962] xref: EMBL:AAA62230.1 xref: EMBL:AAB61242.1 xref: EMBL:AAH12088.1 xref: EMBL:AAM14627.1 xref: UniProtKB:O00703 xref: UniProtKB:Q12962 xref: UniProtKB:Q13175 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005724 ! TAF10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:I0015958 ! atxn7-trrap-3 physical interaction relationship: participates_in CCO:I0015959 ! atxn7-trrap-4 physical interaction relationship: participates_in CCO:I0016130 ! trrap-1-atxn7-1 physical interaction relationship: participates_in CCO:I0017762 ! atxn7-trrap-5 physical interaction relationship: participates_in CCO:I0017887 ! atxn7-trrap physical interaction relationship: participates_in CCO:I0017888 ! trrap-1-atxn7 physical interaction relationship: participates_in CCO:I0018338 ! atxn7-taf10 physical interaction relationship: participates_in CCO:I0019400 ! atxn7-trrap-1 physical interaction relationship: participates_in CCO:I0020321 ! ftl-taf10 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0032858 ! TAF10_HUMAN-N6-methyllysine189 [Term] id: CCO:B0005938 name: TAF9_HUMAN def: "Transcription initiation factor TFIID subunit 9" [UniProtKB:Q16594] synonym: "RNA polymerase II TBP-associated factor subunit G" EXACT [UniProtKB:Q16594] synonym: "STAF31/32" EXACT [UniProtKB:Q16594] synonym: "TAFII-31" EXACT [UniProtKB:Q16594] synonym: "TAFII-32" EXACT [UniProtKB:Q16594] synonym: "TAFII32" EXACT [UniProtKB:Q16594] synonym: "Transcription initiation factor TFIID 31 kDa subunit" EXACT [UniProtKB:Q16594] xref: EMBL:AAA84389.1 xref: EMBL:AAA91318.1 xref: EMBL:AAC50153.1 xref: EMBL:AAH03400.1 xref: EMBL:AAH33320.1 xref: EMBL:AAN84793.1 xref: EMBL:AAV38458.1 xref: UniProtKB:Q16594 xref: UniProtKB:Q5U0D1 xref: UniProtKB:Q9BTS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005727 ! TAF9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007596 ! brca1-trrap-7 physical interaction relationship: participates_in CCO:I0015358 ! rps14-taf9 physical interaction relationship: participates_in CCO:I0015575 ! drap1-taf9 physical interaction relationship: participates_in CCO:I0017576 ! taf9-coil physical interaction relationship: participates_in CCO:I0017587 ! rnf138-taf9 physical interaction relationship: participates_in CCO:I0017588 ! rps14-taf9-1 physical interaction relationship: participates_in CCO:I0017589 ! taf6l-taf9 physical interaction relationship: participates_in CCO:I0017590 ! ube1-taf9 physical interaction relationship: participates_in CCO:I0017623 ! taf9-drap1 physical interaction relationship: participates_in CCO:I0017624 ! taf9-kpna1 physical interaction relationship: participates_in CCO:I0017625 ! taf9-kpna6-1 physical interaction relationship: participates_in CCO:I0019628 ! taf9-eef1a1 physical interaction relationship: participates_in CCO:I0019845 ! taf9-dkfzp564o0523 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014307 ! TAF9_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0071114 ! TAF9_HUMAN-Phosphothreonine159 relationship: transforms_into CCO:B0071115 ! TAF9_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0071116 ! TAF9_HUMAN-Phosphothreonine178 relationship: transforms_into CCO:B0071117 ! TAF9_HUMAN-Phosphoserine181 [Term] id: CCO:B0005940 name: Q9UC27_HUMAN def: "94 kDa epididymal cytokeratin-like protein" [UniProtKB:Q9UC27] xref: UniProtKB:Q9UC27 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007598 ! skp2-skp1 physical interaction [Term] id: CCO:B0005941 name: FBW1B_HUMAN def: "F-box/WD repeat-containing protein 11" [UniProtKB:Q9UKB1] synonym: "F-box and WD repeats protein beta-TrCP2" EXACT [UniProtKB:Q9UKB1] synonym: "F-box/WD repeat-containing protein 1B" EXACT [UniProtKB:Q9UKB1] synonym: "Homologous to Slimb protein" EXACT [UniProtKB:Q9UKB1] synonym: "HOS" EXACT [UniProtKB:Q9UKB1] xref: EMBL:AAF04528.1 xref: EMBL:AAH26213.1 xref: EMBL:BAA31671.1 xref: EMBL:BAA92329.1 xref: EMBL:BAA92330.1 xref: EMBL:BAA92331.1 xref: UniProtKB:Q9P2S8 xref: UniProtKB:Q9P2S9 xref: UniProtKB:Q9UKB1 xref: UniProtKB:Q9Y4C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004620 ! FBXW11_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007599 ! fbxw11-skp1 physical interaction relationship: participates_in CCO:I0007602 ! fbxw11-wee1 physical interaction relationship: participates_in CCO:I0017158 ! nfkbia-fbxw1b-1 physical interaction relationship: participates_in CCO:I0017166 ! nfkbib-fbxw1b physical interaction relationship: participates_in CCO:I0017184 ! nfkbie-fbxw1b physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0005942 name: WASL_HUMAN def: "Neural Wiskott-Aldrich syndrome protein" [UniProtKB:O00401] synonym: "N-WASP" EXACT [UniProtKB:O00401] xref: EMBL:AAH52955.1 xref: EMBL:AAQ96857.1 xref: EMBL:BAA20128.1 xref: UniProtKB:O00401 xref: UniProtKB:Q7Z746 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005911 ! WASL_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:I0007605 ! wasl-lck-1 phosphorylation relationship: participates_in CCO:I0007606 ! wasl-lck-2 phosphorylation relationship: participates_in CCO:I0018879 ! wasl-ptpn2-1 dephosphorylation relationship: participates_in CCO:I0018880 ! wasl-ptpn2-2 phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014654 ! WASL_HUMAN-Phosphotyrosine256 [Term] id: CCO:B0005943 name: APTX_HUMAN def: "Aprataxin" [UniProtKB:Q7Z2E3] synonym: "EC 3.-.-.-" EXACT [UniProtKB:Q7Z2E3] synonym: "FHA-HIT" EXACT [UniProtKB:Q7Z2E3] synonym: "Forkhead-associated domain histidine triad-like protein" EXACT [UniProtKB:Q7Z2E3] xref: EMBL:AAH01628.1 xref: EMBL:AAK91768.1 xref: EMBL:AAP86319.1 xref: EMBL:AAP86320.1 xref: EMBL:AAP86321.1 xref: EMBL:AAP86322.1 xref: EMBL:AAP86323.1 xref: EMBL:AAP86324.1 xref: EMBL:AAP86325.1 xref: EMBL:AAP86326.1 xref: EMBL:AAP86327.1 xref: EMBL:AAP86328.1 xref: EMBL:AAP86329.1 xref: EMBL:AAP86330.1 xref: EMBL:AAP86331.1 xref: EMBL:AAP86332.1 xref: EMBL:BAA90985.1 xref: EMBL:CAD92454.1 xref: EMBL:CAD92455.1 xref: EMBL:CAD92456.1 xref: EMBL:CAD92457.1 xref: EMBL:CAD92458.1 xref: EMBL:CAD92459.1 xref: EMBL:CAD98041.1 xref: EMBL:CAE01427.1 xref: EMBL:CAI15734.1 xref: UniProtKB:Q5T781 xref: UniProtKB:Q7Z2E3 xref: UniProtKB:Q7Z2F3 xref: UniProtKB:Q7Z336 xref: UniProtKB:Q7Z5R5 xref: UniProtKB:Q7Z6V7 xref: UniProtKB:Q7Z6V8 xref: UniProtKB:Q9NXM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004086 ! APTX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002300 ! phosphoglycolate phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005198 ! DNA 5'-adenosine monophosphate hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0007613 ! aptx-cntrob physical interaction relationship: participates_in CCO:I0016140 ! xrcc4-aprataxin-1 physical interaction relationship: participates_in CCO:I0017598 ! aptx-trim37-1 physical interaction relationship: participates_in CCO:I0017599 ! aptx-xrcc4 physical interaction relationship: participates_in CCO:I0018909 ! aptx-cep350 physical interaction relationship: participates_in CCO:I0018910 ! aptx-hivep1 physical interaction relationship: participates_in CCO:I0018911 ! aptx-syt17 physical interaction relationship: participates_in CCO:I0018912 ! aptx-mbp physical interaction relationship: participates_in CCO:I0018913 ! aptx-trim37 physical interaction relationship: participates_in CCO:I0018914 ! aptx-xrcc1 physical interaction relationship: participates_in CCO:I0018915 ! aptx-znf639 physical interaction relationship: participates_in CCO:I0018916 ! aptx-prkcabp physical interaction relationship: participates_in CCO:I0018917 ! aptx-xrcc1-1 physical interaction relationship: participates_in CCO:I0018918 ! aptx-znf639-1 physical interaction relationship: participates_in CCO:P0001482 ! regulation of protein stability [Term] id: CCO:B0005944 name: ATN1_HUMAN def: "Atrophin-1" [UniProtKB:P54259] synonym: "Dentatorubral-pallidoluysian atrophy protein" EXACT [UniProtKB:P54259] xref: EMBL:AAB50276.1 xref: EMBL:AAB51321.1 xref: EMBL:BAA06626.1 xref: EMBL:BAA07534.1 xref: EMBL:BAA23631.1 xref: UniProtKB:P54259 xref: UniProtKB:Q99495 xref: UniProtKB:Q99621 xref: UniProtKB:Q9UEK7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004118 ! ATN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007614 ! atn1-jag2 physical interaction relationship: participates_in CCO:I0007615 ! atn1-jag2-1 physical interaction relationship: participates_in CCO:I0007616 ! atn1-siah1 physical interaction relationship: participates_in CCO:I0007617 ! atn1-siah2 physical interaction relationship: participates_in CCO:I0007618 ! atn1-spag5 physical interaction relationship: participates_in CCO:I0008764 ! atn1-psme3-2 physical interaction relationship: participates_in CCO:I0008781 ! atn1-psme3 physical interaction relationship: participates_in CCO:I0008782 ! atn1-psma3 physical interaction relationship: participates_in CCO:I0008783 ! atn1-psme3-1 physical interaction relationship: participates_in CCO:I0008784 ! atn1-psma3-1 physical interaction relationship: participates_in CCO:I0016161 ! atn1-trip6 physical interaction relationship: participates_in CCO:I0017548 ! baiap2-atn1 physical interaction relationship: participates_in CCO:I0017549 ! runx1t1-atn1 physical interaction relationship: participates_in CCO:I0017550 ! ewsr1-atn1 physical interaction relationship: participates_in CCO:I0017551 ! mdfi-atn1 physical interaction relationship: participates_in CCO:I0017552 ! nck2-atn1 physical interaction relationship: participates_in CCO:I0017600 ! atn1-mdfi physical interaction relationship: participates_in CCO:I0017601 ! atn1-trip6-1 physical interaction relationship: participates_in CCO:I0018919 ! atn1-agrn physical interaction relationship: participates_in CCO:I0018920 ! atn1-cbfa2t2 physical interaction relationship: participates_in CCO:I0018921 ! atn1-cenpj physical interaction relationship: participates_in CCO:I0018922 ! atn1-crip2 physical interaction relationship: participates_in CCO:I0018923 ! atn1-dvl2 physical interaction relationship: participates_in CCO:I0018924 ! atn1-ewsr1 physical interaction relationship: participates_in CCO:I0018925 ! atn1-grn physical interaction relationship: participates_in CCO:I0018926 ! atn1-kiaa0543 physical interaction relationship: participates_in CCO:I0018927 ! atn1-perq1 physical interaction relationship: participates_in CCO:I0018928 ! atn1-pfkl physical interaction relationship: participates_in CCO:I0018929 ! atn1-cbfa2t2-1 physical interaction relationship: participates_in CCO:I0018930 ! atn1-grn-1 physical interaction relationship: participates_in CCO:I0018931 ! atn1-lrp2 physical interaction relationship: participates_in CCO:I0018932 ! atn1-wwp1 physical interaction relationship: participates_in CCO:I0018933 ! atn1-aes physical interaction relationship: participates_in CCO:I0018934 ! atn1-arf3 physical interaction relationship: participates_in CCO:I0018935 ! atn1-dmpk physical interaction relationship: participates_in CCO:I0018936 ! atn1-ecm1 physical interaction relationship: participates_in CCO:I0018937 ! atn1-myst3 physical interaction relationship: participates_in CCO:I0018938 ! atn1-myst4 physical interaction relationship: participates_in CCO:I0018939 ! atn1-rbm9 physical interaction relationship: participates_in CCO:I0018940 ! atn1-rere physical interaction relationship: participates_in CCO:I0019157 ! rere-atn1 physical interaction relationship: participates_in CCO:I0019161 ! rere-atn1-1 physical interaction relationship: transforms_into CCO:B0010660 ! ATN1_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0010661 ! ATN1_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0010662 ! ATN1_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0010663 ! ATN1_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0010664 ! ATN1_HUMAN-Phosphoserine103 relationship: transforms_into CCO:B0010665 ! ATN1_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0010666 ! ATN1_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0010667 ! ATN1_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0010668 ! ATN1_HUMAN-Phosphoserine627 relationship: transforms_into CCO:B0010669 ! ATN1_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0010670 ! ATN1_HUMAN-Phosphothreonine648 relationship: transforms_into CCO:B0010671 ! ATN1_HUMAN-Phosphoserine656 relationship: transforms_into CCO:B0010672 ! ATN1_HUMAN-Phosphothreonine664 relationship: transforms_into CCO:B0010673 ! ATN1_HUMAN-Phosphoserine734 relationship: transforms_into CCO:B0010674 ! ATN1_HUMAN-Phosphoserine741 relationship: transforms_into CCO:B0010675 ! ATN1_HUMAN-Phosphoserine743 relationship: transforms_into CCO:B0063655 ! ATN1_HUMAN-Phosphothreonine646 relationship: transforms_into CCO:B0063656 ! ATN1_HUMAN-Phosphotyrosine729 [Term] id: CCO:B0005945 name: ATX7_HUMAN def: "Ataxin-7" [UniProtKB:O15265] synonym: "Spinocerebellar ataxia type 7 protein" EXACT [UniProtKB:O15265] xref: EMBL:AAC19162.1 xref: EMBL:AAC19163.1 xref: EMBL:AAC39765.1 xref: EMBL:CAA04154.1 xref: UniProtKB:O15265 xref: UniProtKB:O75328 xref: UniProtKB:O75329 xref: UniProtKB:Q9Y6P8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004128 ! ATXN7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007626 ! atxn7-tp53bp2 physical interaction relationship: participates_in CCO:I0015958 ! atxn7-trrap-3 physical interaction relationship: participates_in CCO:I0015959 ! atxn7-trrap-4 physical interaction relationship: participates_in CCO:I0016129 ! atxn7-trrap-6 physical interaction relationship: participates_in CCO:I0016130 ! trrap-1-atxn7-1 physical interaction relationship: participates_in CCO:I0017762 ! atxn7-trrap-5 physical interaction relationship: participates_in CCO:I0017887 ! atxn7-trrap physical interaction relationship: participates_in CCO:I0017888 ! trrap-1-atxn7 physical interaction relationship: participates_in CCO:I0018338 ! atxn7-taf10 physical interaction relationship: participates_in CCO:I0019124 ! atxn7-prkcabp physical interaction relationship: participates_in CCO:I0019125 ! atxn7-rad23a physical interaction relationship: participates_in CCO:I0019276 ! atxn7-trrap-2 acetylation relationship: participates_in CCO:I0019400 ! atxn7-trrap-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010719 ! ATX7_HUMAN-Phosphoserine840 relationship: transforms_into CCO:B0010720 ! ATX7_HUMAN-Phosphoserine849 relationship: transforms_into CCO:B0010721 ! ATX7_HUMAN-Phosphothreonine854 [Term] id: CCO:B0005946 name: Q8IY68_HUMAN def: "Ataxin-7-like protein 3." [UniProtKB:Q8IY68] xref: EMBL:AAH37418.1 xref: UniProtKB:Q8IY68 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006019 ! ATXN7L3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007627 ! atxn7l3-sertad1 physical interaction relationship: participates_in CCO:I0017617 ! atxn7l3-usp6 physical interaction relationship: participates_in CCO:I0019128 ! atxn7l3-prkcabp physical interaction [Term] id: CCO:B0005947 name: PICK1_HUMAN def: "PRKCA-binding protein" [UniProtKB:Q9NRD5] synonym: "Protein interacting with C kinase 1" EXACT [UniProtKB:Q9NRD5] synonym: "Protein kinase C-alpha-binding protein" EXACT [UniProtKB:Q9NRD5] xref: EMBL:AAF97502.1 xref: EMBL:AAH17561.1 xref: EMBL:BAA89294.1 xref: EMBL:CAB37478.1 xref: EMBL:CAB41082.1 xref: EMBL:CAG30436.1 xref: UniProtKB:O95906 xref: UniProtKB:Q9NRD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005313 ! PICK1_human relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000740 ! postsynaptic density relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0007629 ! gfi1-prkcabp physical interaction relationship: participates_in CCO:I0007671 ! gfi1b-prkcabp physical interaction relationship: participates_in CCO:I0007690 ! gfi1b-prkcabp-1 physical interaction relationship: participates_in CCO:I0016313 ! accn2-prkpcabp-2 physical interaction relationship: participates_in CCO:I0017901 ! accn2-prkcabp-1 physical interaction relationship: participates_in CCO:I0017902 ! accn2-prkcabp-3 colocalization relationship: participates_in CCO:I0018352 ! acnn1-prkcabp-1 physical interaction relationship: participates_in CCO:I0018353 ! accn1-prkcabp-1 physical interaction relationship: participates_in CCO:I0018567 ! accn1-prkcabp-2 physical interaction relationship: participates_in CCO:I0018895 ! ubqln4-prkcabp physical interaction relationship: participates_in CCO:I0018903 ! ubqln4-prkcabp-1 physical interaction relationship: participates_in CCO:I0018916 ! aptx-prkcabp physical interaction relationship: participates_in CCO:I0019123 ! atxn3-prkcabp physical interaction relationship: participates_in CCO:I0019124 ! atxn7-prkcabp physical interaction relationship: participates_in CCO:I0019128 ! atxn7l3-prkcabp physical interaction relationship: participates_in CCO:I0019131 ! cic-prkcabp physical interaction relationship: participates_in CCO:I0019137 ! coil-prkcabp physical interaction relationship: participates_in CCO:I0019141 ! coil-prkcabp-1 physical interaction relationship: participates_in CCO:I0019145 ! coil-prkcabp-2 physical interaction relationship: participates_in CCO:I0019147 ! fxn-prkcabp physical interaction relationship: participates_in CCO:I0019153 ! prkcg-prkcabp physical interaction relationship: participates_in CCO:I0019154 ! prkcg-prkcabp-1 physical interaction relationship: participates_in CCO:I0019169 ! sacs-prkcabp physical interaction relationship: participates_in CCO:I0019177 ! usp7-prkcabp physical interaction relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0002145 ! DNA methylation during embryonic development relationship: participates_in CCO:P0002146 ! DNA methylation during gametogenesis relationship: participates_in CCO:P0002160 ! receptor clustering [Term] id: CCO:B0005948 name: ACTN1_HUMAN def: "Alpha-actinin-1" [UniProtKB:P12814] synonym: "Alpha-actinin cytoskeletal isoform" EXACT [UniProtKB:P12814] synonym: "F-actin cross-linking protein" EXACT [UniProtKB:P12814] synonym: "Non-muscle alpha-actinin-1" EXACT [UniProtKB:P12814] xref: EMBL:AAA51582.1 xref: EMBL:AAH03576.1 xref: EMBL:AAH15766.1 xref: EMBL:AAP35871.1 xref: EMBL:CAA33803.1 xref: EMBL:CAA38970.1 xref: UniProtKB:P12814 xref: UniProtKB:Q9BTN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004021 ! ACTN1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003605 ! vinculin binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000934 ! Z disc relationship: located_in CCO:C0001136 ! pseudopodium relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007630 ! gfi1b-actn1 physical interaction relationship: participates_in CCO:I0007682 ! gfi1b-actn1-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015102 ! actn1-xrcc4 physical interaction relationship: participates_in CCO:I0015578 ! actn1-magea11 physical interaction relationship: participates_in CCO:I0015831 ! actn1-myoz physical interaction relationship: participates_in CCO:I0015982 ! src-actn1-1 physical interaction relationship: participates_in CCO:I0018875 ! ptpn1-actn1-1 dephosphorylation relationship: participates_in CCO:I0018876 ! src-actn1-2 physical interaction relationship: participates_in CCO:I0019111 ! atxn2-actn1 physical interaction relationship: participates_in CCO:I0019117 ! atxn2-actn1-1 physical interaction relationship: participates_in CCO:I0019132 ! coil-actn1 physical interaction relationship: participates_in CCO:I0019142 ! coil-actn1-1 physical interaction relationship: participates_in CCO:I0019146 ! fxn-actn1 physical interaction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0003072 ! negative regulation of cell motility relationship: transforms_into CCO:B0010446 ! ACTN1_HUMAN-Phosphotyrosine12 relationship: transforms_into CCO:B0010447 ! ACTN1_HUMAN-Phosphothreonine50 relationship: transforms_into CCO:B0010448 ! ACTN1_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0065398 ! ACTN1_HUMAN-Phosphotyrosine193 [Term] id: CCO:B0005949 name: AGRIN_HUMAN def: "Agrin precursor" [UniProtKB:O00468] xref: EMBL:AAB52917.1 xref: EMBL:AAC39776.1 xref: EMBL:AAH04220.2 xref: EMBL:AAH07649.1 xref: EMBL:AAH34009.1 xref: EMBL:AAH63620.1 xref: EMBL:BAD52440.1 xref: EMBL:CAI15575.2 xref: UniProtKB:O00468 xref: UniProtKB:Q5SVA2 xref: UniProtKB:Q60FE1 xref: UniProtKB:Q7KYS8 xref: UniProtKB:Q8N4J5 xref: UniProtKB:Q96IC1 xref: UniProtKB:Q9BTD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006344 ! AGRN_human relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005825 ! laminin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000228 ! basal lamina relationship: participates_in CCO:I0007631 ! gfi1b-agrn physical interaction relationship: participates_in CCO:I0018919 ! atn1-agrn physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: participates_in CCO:P0002160 ! receptor clustering [Term] id: CCO:B0005950 name: BECN1_HUMAN def: "Beclin-1" [UniProtKB:Q14457] synonym: "Coiled-coil myosin-like BCL2-interacting protein" EXACT [UniProtKB:Q14457] synonym: "Protein GT197" EXACT [UniProtKB:Q14457] xref: EMBL:AAB59573.1 xref: EMBL:AAC68653.1 xref: EMBL:AAD27650.1 xref: EMBL:AAH10276.1 xref: UniProtKB:O75595 xref: UniProtKB:Q14457 xref: UniProtKB:Q9UNA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004157 ! BECN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:I0007632 ! gfi1b-becn1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0005951 name: BRE_HUMAN def: "Protein BRE" [UniProtKB:Q9NXR7] synonym: "Brain and reproductive organ-expressed protein" EXACT [UniProtKB:Q9NXR7] synonym: "BRCA1/BRCA2-containing complex subunit 45" EXACT [UniProtKB:Q9NXR7] xref: EMBL:AAA64231.1 xref: EMBL:AAB69387.1 xref: EMBL:AAH01251.1 xref: EMBL:AAL17818.1 xref: EMBL:AAR30499.1 xref: EMBL:BAA90943.1 xref: UniProtKB:Q13880 xref: UniProtKB:Q96P06 xref: UniProtKB:Q9NXR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004190 ! BRE_human relationship: has_function CCO:F0000054 ! peroxisome targeting sequence binding relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000027 ! nuclear ubiquitin ligase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007634 ! gfi1b-bre physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis [Term] id: CCO:B0005952 name: CT012_HUMAN def: "Ankyrin repeat-containing protein C20orf12" [UniProtKB:Q9NVP4] xref: EMBL:AAZ13595.1 xref: EMBL:BAA91706.1 xref: EMBL:BAB70949.1 xref: EMBL:BAD18596.1 xref: EMBL:CAH18182.1 xref: EMBL:CAI12510.1 xref: EMBL:CAI12511.1 xref: EMBL:CAI21830.1 xref: EMBL:CAI21831.1 xref: UniProtKB:Q4F7X1 xref: UniProtKB:Q5QPD9 xref: UniProtKB:Q5QPE0 xref: UniProtKB:Q68DN8 xref: UniProtKB:Q6ZMX9 xref: UniProtKB:Q96NF0 xref: UniProtKB:Q9H1E0 xref: UniProtKB:Q9H442 xref: UniProtKB:Q9NVP4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004411 ! C20orf12_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0007635 ! gfi1b-c20orf12 physical interaction [Term] id: CCO:B0005953 name: Q8NDD3_HUMAN def: "Putative uncharacterized protein DKFZp586M1819" [UniProtKB:Q8NDD3] xref: EMBL:CAD38930.1 xref: UniProtKB:Q8NDD3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006026 ! DKFZp586M1819_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007638 ! gfi1b-dkfzp586m1819 physical interaction [Term] id: CCO:B0005954 name: DTNA_HUMAN def: "Dystrobrevin alpha" [UniProtKB:Q9Y4J8] synonym: "Dystrobrevin-alpha" EXACT [UniProtKB:Q9Y4J8] synonym: "Dystrophin-related protein 3" EXACT [UniProtKB:Q9Y4J8] xref: EMBL:AAB58541.1 xref: EMBL:AAB58542.1 xref: EMBL:AAB58543.1 xref: EMBL:AAC50424.1 xref: EMBL:AAC50425.1 xref: EMBL:AAC50426.1 xref: EMBL:AAC50429.1 xref: EMBL:AAC50430.1 xref: EMBL:AAC50431.1 xref: EMBL:CAA08769.1 xref: UniProtKB:O15332 xref: UniProtKB:O15333 xref: UniProtKB:O75697 xref: UniProtKB:Q13197 xref: UniProtKB:Q13198 xref: UniProtKB:Q13199 xref: UniProtKB:Q13498 xref: UniProtKB:Q13499 xref: UniProtKB:Q13500 xref: UniProtKB:Q9Y4J8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004517 ! DTNA_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0007639 ! gfi1b-dtna physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005955 name: FBLN3_HUMAN def: "EGF-containing fibulin-like extracellular matrix protein 1 precursor" [UniProtKB:Q12805] synonym: "Extracellular protein S1-5" EXACT [UniProtKB:Q12805] synonym: "FIBL-3" EXACT [UniProtKB:Q12805] synonym: "Fibrillin-like protein" EXACT [UniProtKB:Q12805] synonym: "Fibulin-3" EXACT [UniProtKB:Q12805] xref: EMBL:AAA65590.1 xref: EMBL:AAH14410.1 xref: EMBL:AAH98561.1 xref: EMBL:AAK11491.1 xref: UniProtKB:Q12805 xref: UniProtKB:Q541U7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004615 ! EFEMP1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:I0007640 ! gfi1b-efemp1 physical interaction relationship: participates_in CCO:I0007686 ! gfi1b-efemp1-1 physical interaction relationship: participates_in CCO:I0018802 ! araf-efemp1 physical interaction relationship: participates_in CCO:I0018808 ! araf-efemp1-1 physical interaction relationship: participates_in CCO:I0018822 ! araf-efemp1-2 physical interaction relationship: participates_in CCO:I0019165 ! rere-efemp1 physical interaction relationship: participates_in CCO:I0019370 ! raf1-efemp1 physical interaction [Term] id: CCO:B0005956 name: MEGF6_HUMAN def: "Multiple epidermal growth factor-like domains 6 precursor" [UniProtKB:O75095] synonym: "EGF-like domain-containing protein 3" EXACT [UniProtKB:O75095] synonym: "Multiple EGF-like domain protein 3" EXACT [UniProtKB:O75095] xref: EMBL:BAA32467.2 xref: EMBL:CAH70834.1 xref: EMBL:CAI14334.1 xref: UniProtKB:O75095 xref: UniProtKB:Q5VV39 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005081 ! MEGF6_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0007642 ! gfi1b-megf6 physical interaction [Term] id: CCO:B0005957 name: MEGF8_HUMAN def: "Multiple epidermal growth factor-like domains 8" [UniProtKB:Q7Z7M0] synonym: "EGF-like domain-containing protein 4" EXACT [UniProtKB:Q7Z7M0] synonym: "Multiple EGF-like domain protein 4" EXACT [UniProtKB:Q7Z7M0] xref: EMBL:AAP35084.1 xref: EMBL:BAA32469.2 xref: UniProtKB:O75097 xref: UniProtKB:Q7Z7M0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005082 ! MEGF8_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007643 ! gfi1b-megf8 physical interaction [Term] id: CCO:B0005958 name: EGFL7_HUMAN def: "EGF-like domain-containing protein 7 precursor" [UniProtKB:Q9UHF1] synonym: "Multiple EGF-like domain protein 7" EXACT [UniProtKB:Q9UHF1] synonym: "Multiple epidermal growth factor-like domain protein 7" EXACT [UniProtKB:Q9UHF1] synonym: "NOTCH4-like protein" EXACT [UniProtKB:Q9UHF1] synonym: "Vascular endothelial statin" EXACT [UniProtKB:Q9UHF1] synonym: "VE-statin" EXACT [UniProtKB:Q9UHF1] synonym: "ZNEU1" EXACT [UniProtKB:Q9UHF1] xref: EMBL:AAF01429.1 xref: EMBL:AAH12377.1 xref: EMBL:AAH88371.1 xref: EMBL:AAQ89260.1 xref: EMBL:AAQ89261.1 xref: EMBL:AAQ89262.1 xref: EMBL:BAD01469.1 xref: EMBL:CAC21666.1 xref: EMBL:CAH71721.1 xref: UniProtKB:Q5M7Y5 xref: UniProtKB:Q5VUD5 xref: UniProtKB:Q96EG0 xref: UniProtKB:Q9UHF1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004551 ! EGFL7_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0007644 ! gfi1b-egfl7 physical interaction [Term] id: CCO:B0005959 name: FBLN1_HUMAN def: "Fibulin-1 precursor" [UniProtKB:P23142] synonym: "FIBL-1" EXACT [UniProtKB:P23142] xref: EMBL:AAB17099.1 xref: EMBL:AAG17241.1 xref: EMBL:AAH22497.1 xref: EMBL:AAK37822.1 xref: EMBL:AAK82945.1 xref: EMBL:CAA37770.1 xref: EMBL:CAA37771.1 xref: EMBL:CAA37772.1 xref: EMBL:CAI18930.1 xref: EMBL:CAI19628.1 xref: EMBL:CAI41717.1 xref: UniProtKB:P23142 xref: UniProtKB:P23143 xref: UniProtKB:P23144 xref: UniProtKB:P37888 xref: UniProtKB:Q5TIC4 xref: UniProtKB:Q8TBH8 xref: UniProtKB:Q9HBQ5 xref: UniProtKB:Q9UC21 xref: UniProtKB:Q9UGR4 xref: UniProtKB:Q9UH41 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004614 ! FBLN1_human relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0007645 ! gfi1b-fbln1 physical interaction [Term] id: CCO:B0005960 name: GRIP2_HUMAN def: "Glutamate receptor-interacting protein 2" [UniProtKB:Q9C0E4] synonym: "GRIP2 protein" EXACT [UniProtKB:Q9C0E4] xref: EMBL:BAB15797.1 xref: EMBL:BAB21810.2 xref: EMBL:BAB84971.1 xref: UniProtKB:Q8TEH9 xref: UniProtKB:Q9C0E4 xref: UniProtKB:Q9H7H3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004728 ! GRIP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007646 ! gfi1b-grip2 physical interaction [Term] id: CCO:B0005961 name: GRN_HUMAN def: "Granulins precursor" [UniProtKB:P28799] synonym: "PEPI" EXACT [UniProtKB:P28799] synonym: "Proepithelin" EXACT [UniProtKB:P28799] xref: EMBL:AAA58617.1 xref: EMBL:AAC09359.1 xref: EMBL:AAH00324.1 xref: EMBL:AAH10577.1 xref: EMBL:CAA44196.1 xref: UniProtKB:P23781 xref: UniProtKB:P23782 xref: UniProtKB:P23783 xref: UniProtKB:P23784 xref: UniProtKB:P28799 xref: UniProtKB:Q9BWE7 xref: UniProtKB:Q9UCH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004730 ! GRN_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007647 ! gfi1b-grn physical interaction relationship: participates_in CCO:I0015363 ! c1orf117-grn physical interaction relationship: participates_in CCO:I0015782 ! grn-hoxa1 physical interaction relationship: participates_in CCO:I0018925 ! atn1-grn physical interaction relationship: participates_in CCO:I0018930 ! atn1-grn-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0005962 name: HECW1_HUMAN def: "E3 ubiquitin-protein ligase HECW1" [UniProtKB:Q76N89] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q76N89] synonym: "HECT, C2 and WW domain-containing protein 1" EXACT [UniProtKB:Q76N89] synonym: "hNEDL1" EXACT [UniProtKB:Q76N89] synonym: "NEDD4-like E3 ubiquitin-protein ligase 1" EXACT [UniProtKB:Q76N89] xref: EMBL:BAA20780.2 xref: EMBL:BAB13352.1 xref: UniProtKB:O15036 xref: UniProtKB:Q76N89 xref: UniProtKB:Q9HCC7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004798 ! HECW1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007648 ! gfi1b-hecw1 physical interaction [Term] id: CCO:B0005963 name: Q6P593_HUMAN def: "IFFO protein" [UniProtKB:Q6P593] xref: EMBL:AAH63004.1 xref: UniProtKB:Q6P593 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014372 ! IFFO_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007651 ! gfi1b-hom_tes_103 physical interaction [Term] id: CCO:B0005964 name: PGBM_HUMAN def: "Basement membrane-specific heparan sulfate proteoglycan core protein precursor" [UniProtKB:P98160] synonym: "HSPG" EXACT [UniProtKB:P98160] synonym: "Perlecan" EXACT [UniProtKB:P98160] synonym: "PLC" EXACT [UniProtKB:P98160] xref: EMBL:AAA52699.1 xref: EMBL:AAA52700.1 xref: EMBL:AAB21121.2 xref: EMBL:CAA44373.1 xref: EMBL:CAC18534.1 xref: UniProtKB:P98160 xref: UniProtKB:Q16287 xref: UniProtKB:Q9H3V5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005303 ! HSPG2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:I0007652 ! gfi1b-hspg2 physical interaction [Term] id: CCO:B0005965 name: ANKS3_HUMAN def: "Ankyrin repeat and SAM domain-containing protein 3" [UniProtKB:Q6ZW76] xref: EMBL:BAB85563.1 xref: EMBL:BAC85629.1 xref: UniProtKB:Q6ZW76 xref: UniProtKB:Q8TF25 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004060 ! ANKS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007655 ! gfi1b-anks3 physical interaction relationship: transforms_into CCO:B0010529 ! ANKS3_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0010530 ! ANKS3_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0010531 ! ANKS3_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0010532 ! ANKS3_HUMAN-Phosphoserine320 [Term] id: CCO:B0005966 name: KIF17_HUMAN def: "Kinesin-like protein KIF17" [UniProtKB:Q9P2E2] synonym: "KIF3-related motor protein" EXACT [UniProtKB:Q9P2E2] xref: EMBL:AAD01428.1 xref: EMBL:AAH36871.1 xref: EMBL:AAH65927.1 xref: EMBL:AAR33039.1 xref: EMBL:BAA92643.2 xref: EMBL:CAH73471.1 xref: EMBL:CAI23390.1 xref: UniProtKB:O95077 xref: UniProtKB:Q53YS6 xref: UniProtKB:Q5VWA9 xref: UniProtKB:Q6GSA8 xref: UniProtKB:Q8N411 xref: UniProtKB:Q9P2E2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004942 ! KIF17_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0007656 ! gfi1b-kif17 physical interaction [Term] id: CCO:B0005967 name: LAMB1_HUMAN def: "Laminin subunit beta-1 precursor" [UniProtKB:P07942] synonym: "Laminin B1 chain" EXACT [UniProtKB:P07942] xref: EMBL:AAA59482.1 xref: EMBL:AAA59485.1 xref: EMBL:AAA59486.1 xref: EMBL:AAA59487.1 xref: EMBL:AAI13456.1 xref: EMBL:EAL24388.1 xref: UniProtKB:P07942 xref: UniProtKB:Q14D91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004969 ! LAMB1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0000230 ! laminin-2 complex relationship: located_in CCO:C0001757 ! laminin-8 complex relationship: located_in CCO:C0001759 ! laminin-10 complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0007657 ! gfi1b-lamb1 physical interaction relationship: participates_in CCO:I0019127 ! atxn7l2-lamb1 physical interaction relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0005968 name: MATR3_HUMAN def: "Matrin-3" [UniProtKB:P43243] xref: EMBL:AAF17217.1 xref: EMBL:AAH15031.1 xref: EMBL:BAA34443.2 xref: UniProtKB:P43243 xref: UniProtKB:Q9UHW0 xref: UniProtKB:Q9UQ27 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005032 ! MATR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007659 ! gfi1b-matr3 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015194 ! hnrpk-matr3 physical interaction relationship: participates_in CCO:I0016700 ! map3k3-matr3 physical interaction relationship: participates_in CCO:I0016797 ! nfkb2-matr3 physical interaction relationship: transforms_into CCO:B0012782 ! MATR3_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0012783 ! MATR3_HUMAN-Phosphoserine195 relationship: transforms_into CCO:B0012784 ! MATR3_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0012785 ! MATR3_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0012786 ! MATR3_HUMAN-Phosphoserine596 relationship: transforms_into CCO:B0012787 ! MATR3_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0012788 ! MATR3_HUMAN-Phosphoserine604 relationship: transforms_into CCO:B0012789 ! MATR3_HUMAN-Phosphoserine654 relationship: transforms_into CCO:B0012790 ! MATR3_HUMAN-Phosphoserine671 relationship: transforms_into CCO:B0012791 ! MATR3_HUMAN-Phosphoserine673 relationship: transforms_into CCO:B0012792 ! MATR3_HUMAN-Phosphoserine674 relationship: transforms_into CCO:B0012793 ! MATR3_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0048315 ! MATR3_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0068005 ! MATR3_HUMAN-Phosphoserine533 [Term] id: CCO:B0005969 name: TRIM1_HUMAN def: "Midline-2" [UniProtKB:Q9UJV3] synonym: "Midin-2" EXACT [UniProtKB:Q9UJV3] synonym: "Midline defect 2" EXACT [UniProtKB:Q9UJV3] synonym: "RING finger protein 60" EXACT [UniProtKB:Q9UJV3] synonym: "Tripartite motif-containing protein 1" EXACT [UniProtKB:Q9UJV3] xref: EMBL:AAF07341.1 xref: EMBL:AAH17707.1 xref: EMBL:AAP35309.1 xref: EMBL:CAB56154.1 xref: EMBL:CAI42073.1 xref: EMBL:CAO72053.1 xref: UniProtKB:A6NEL8 xref: UniProtKB:A6PVI5 xref: UniProtKB:Q5JYF5 xref: UniProtKB:Q8WWK1 xref: UniProtKB:Q9UJR9 xref: UniProtKB:Q9UJV3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005834 ! MID2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0007660 ! gfi1b-mid2 physical interaction [Term] id: CCO:B0005970 name: MON1A_HUMAN def: "Vacuolar fusion protein MON1 homolog A" [UniProtKB:Q86VX9] xref: EMBL:AAH06299.1 xref: EMBL:AAH09459.1 xref: EMBL:AAH47022.1 xref: EMBL:BAC03790.1 xref: UniProtKB:Q86VX9 xref: UniProtKB:Q8NAV7 xref: UniProtKB:Q9BRF3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005111 ! MON1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007661 ! gfi1b-mon1a physical interaction relationship: transforms_into CCO:B0012969 ! MON1A_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0012970 ! MON1A_HUMAN-Phosphotyrosine57 relationship: transforms_into CCO:B0012971 ! MON1A_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0012972 ! MON1A_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0068249 ! MON1A_HUMAN-Phosphoserine31 [Term] id: CCO:B0005971 name: MYH14_HUMAN def: "Myosin-14" [UniProtKB:Q7Z406] synonym: "Myosin heavy chain 14" EXACT [UniProtKB:Q7Z406] synonym: "Myosin heavy chain, non-muscle IIc" EXACT [UniProtKB:Q7Z406] synonym: "NMHC II-C" EXACT [UniProtKB:Q7Z406] synonym: "Non-muscle myosin heavy chain IIc" EXACT [UniProtKB:Q7Z406] xref: EMBL:AAH00676.2 xref: EMBL:AAH04396.1 xref: EMBL:AAH07877.2 xref: EMBL:AAH18933.2 xref: EMBL:AAO39147.1 xref: EMBL:AAP34449.1 xref: EMBL:BAB14735.1 xref: EMBL:BAC98374.1 xref: EMBL:CAI56791.1 xref: UniProtKB:Q5CZ75 xref: UniProtKB:Q6XYE4 xref: UniProtKB:Q76B62 xref: UniProtKB:Q7Z406 xref: UniProtKB:Q8WV23 xref: UniProtKB:Q96I22 xref: UniProtKB:Q9BT27 xref: UniProtKB:Q9BW35 xref: UniProtKB:Q9H882 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005143 ! MYH14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007662 ! gfi1b-myh14 physical interaction relationship: participates_in CCO:I0016440 ! chuk-myh14 physical interaction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0013066 ! MYH14_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0068374 ! MYH14_HUMAN-Phosphotyrosine778 [Term] id: CCO:B0005972 name: NELF_HUMAN def: "Nasal embryonic luteinizing hormone-releasing hormone factor" [UniProtKB:Q6X4W1] synonym: "Nasal embryonic LHRH factor" EXACT [UniProtKB:Q6X4W1] xref: EMBL:AAH72412.1 xref: EMBL:AAP83576.1 xref: EMBL:AAP83577.1 xref: EMBL:AAP83578.1 xref: EMBL:AAP83579.1 xref: EMBL:AAP83580.1 xref: EMBL:BAB55139.1 xref: EMBL:BAC11086.1 xref: EMBL:CAB97524.1 xref: EMBL:CAB97525.1 xref: EMBL:CAB97542.1 xref: EMBL:CAI14577.1 xref: EMBL:CAI14578.1 xref: UniProtKB:Q6X4V7 xref: UniProtKB:Q6X4V8 xref: UniProtKB:Q6X4V9 xref: UniProtKB:Q6X4W1 xref: UniProtKB:Q8N2M2 xref: UniProtKB:Q96SY1 xref: UniProtKB:Q9NPM4 xref: UniProtKB:Q9NPP3 xref: UniProtKB:Q9NPS3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005180 ! NELF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007663 ! gfi1b-nelf physical interaction relationship: transforms_into CCO:B0013157 ! NELF_HUMAN-Phosphoserine288 [Term] id: CCO:B0005973 name: NELL1_HUMAN def: "Protein kinase C-binding protein NELL1 precursor" [UniProtKB:Q92832] synonym: "NEL-like protein 1" EXACT [UniProtKB:Q92832] synonym: "Nel-related protein 1" EXACT [UniProtKB:Q92832] xref: EMBL:AAB06946.1 xref: EMBL:AAH96101.1 xref: EMBL:BAA11680.1 xref: UniProtKB:Q4VB90 xref: UniProtKB:Q92832 xref: UniProtKB:Q9Y472 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005181 ! NELL1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0007664 ! gfi1b-nell1 physical interaction [Term] id: CCO:B0005974 name: NOTC1_HUMAN def: "Neurogenic locus notch homolog protein 1 precursor" [UniProtKB:P46531] synonym: "hN1" EXACT [UniProtKB:P46531] synonym: "Notch 1" EXACT [UniProtKB:P46531] synonym: "Translocation-associated notch protein TAN-1" EXACT [UniProtKB:P46531] xref: EMBL:AAA60614.1 xref: EMBL:AAG33848.1 xref: EMBL:BAD93110.1 xref: EMBL:CAI13934.1 xref: EMBL:CAI16149.1 xref: UniProtKB:P46531 xref: UniProtKB:Q59ED8 xref: UniProtKB:Q5SXM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005208 ! NOTCH1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007666 ! gfi1b-notch1 physical interaction relationship: participates_in CCO:I0016319 ! maml-notch physical interaction relationship: participates_in CCO:I0017377 ! rbpsuh-notch1 physical interaction relationship: participates_in CCO:I0017378 ! rbpsuh-skiip-3 physical interaction relationship: participates_in CCO:I0018654 ! notch1-skip-1 physical interaction relationship: participates_in CCO:I0019258 ! notch1-skiip-1 physical interaction relationship: participates_in CCO:I0019388 ! rbpsuh-notch1-1 physical interaction relationship: participates_in CCO:I0020384 ! notch1-g22p1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002476 ! negative regulation of myoblast differentiation [Term] id: CCO:B0005975 name: Q5TB27_HUMAN def: "Phosphodiesterase 4D interacting protein (Myomegalin)" [UniProtKB:Q5TB27] xref: EMBL:CAI22526.1 xref: UniProtKB:Q5TB27 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006001 ! PDE4DIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007667 ! gfi1b-pde4dip physical interaction [Term] id: CCO:B0005976 name: PDLI5_HUMAN def: "PDZ and LIM domain protein 5" [UniProtKB:Q96HC4] synonym: "Enigma homolog" EXACT [UniProtKB:Q96HC4] synonym: "Enigma-like PDZ and LIM domains protein" EXACT [UniProtKB:Q96HC4] xref: EMBL:AAC15767.1 xref: EMBL:AAH08741.1 xref: EMBL:AAP35992.1 xref: EMBL:AAT06739.1 xref: EMBL:BAF84313.1 xref: UniProtKB:A8K6F9 xref: UniProtKB:O60705 xref: UniProtKB:Q5UW38 xref: UniProtKB:Q96HC4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005292 ! PDLIM5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0007668 ! gfi1b-enh physical interaction relationship: transforms_into CCO:B0013464 ! PDLI5_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0013465 ! PDLI5_HUMAN-Phosphothreonine110 relationship: transforms_into CCO:B0013466 ! PDLI5_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0013467 ! PDLI5_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0013468 ! PDLI5_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0013469 ! PDLI5_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0013470 ! PDLI5_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0013471 ! PDLI5_HUMAN-Phosphotyrosine251 relationship: transforms_into CCO:B0013472 ! PDLI5_HUMAN-Phosphoserine309 relationship: transforms_into CCO:B0013473 ! PDLI5_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0013474 ! PDLI5_HUMAN-Phosphoserine335 [Term] id: CCO:B0005977 name: PDZD4_HUMAN def: "PDZ domain-containing protein 4" [UniProtKB:Q76G19] synonym: "PDZ domain-containing RING finger protein 4-like protein" EXACT [UniProtKB:Q76G19] xref: EMBL:AAH02606.2 xref: EMBL:AAH80584.1 xref: EMBL:BAA95968.1 xref: EMBL:BAC03666.1 xref: EMBL:BAD16631.1 xref: UniProtKB:Q76G19 xref: UniProtKB:Q8NB75 xref: UniProtKB:Q9BUH9 xref: UniProtKB:Q9P284 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005296 ! PDZD4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007669 ! gfi1b-pdzk4 physical interaction [Term] id: CCO:B0005978 name: PHC2_HUMAN def: "Polyhomeotic-like protein 2" [UniProtKB:Q8IXK0] synonym: "Early development regulatory protein 2" EXACT [UniProtKB:Q8IXK0] synonym: "hPH2" EXACT [UniProtKB:Q8IXK0] xref: EMBL:AAH15450.1 xref: EMBL:AAH28396.3 xref: EMBL:AAH29269.1 xref: EMBL:AAH68573.1 xref: EMBL:AAH92492.1 xref: EMBL:AAI10864.2 xref: EMBL:AAI30631.1 xref: EMBL:BAC87622.1 xref: EMBL:CAB44779.1 xref: EMBL:CAD11673.1 xref: EMBL:CAI13955.1 xref: EMBL:CAI13956.1 xref: EMBL:CAI13957.1 xref: UniProtKB:A1L4Q1 xref: UniProtKB:Q2TAL3 xref: UniProtKB:Q5T0C1 xref: UniProtKB:Q6NUJ6 xref: UniProtKB:Q6ZQR1 xref: UniProtKB:Q8IXK0 xref: UniProtKB:Q8N306 xref: UniProtKB:Q8TAG8 xref: UniProtKB:Q96BL4 xref: UniProtKB:Q9Y4Y7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005308 ! PHC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007670 ! gfi1b-phc2 physical interaction relationship: transforms_into CCO:B0013502 ! PHC2_HUMAN-Phosphoserine701 relationship: transforms_into CCO:B0013503 ! PHC2_HUMAN-Phosphoserine704 relationship: transforms_into CCO:B0013504 ! PHC2_HUMAN-Phosphoserine733 relationship: transforms_into CCO:B0013505 ! PHC2_HUMAN-Phosphoserine745 [Term] id: CCO:B0005979 name: RFIP4_HUMAN def: "Rab11 family-interacting protein 4" [UniProtKB:Q86YS3] synonym: "Rab11-FIP4" EXACT [UniProtKB:Q86YS3] xref: EMBL:AAH93914.1 xref: EMBL:AAI01518.1 xref: EMBL:AAO21970.1 xref: EMBL:BAB47450.1 xref: EMBL:BAC05045.1 xref: EMBL:CAC44535.1 xref: EMBL:CAD38543.1 xref: UniProtKB:Q52LI1 xref: UniProtKB:Q86YS3 xref: UniProtKB:Q8N829 xref: UniProtKB:Q8NDT7 xref: UniProtKB:Q969D8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005474 ! RAB11FIP4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002023 ! recycling endosome membrane relationship: participates_in CCO:I0007672 ! gfi1b-rab11fip4 physical interaction [Term] id: CCO:B0005980 name: ZN363_HUMAN def: "RING finger and CHY zinc finger domain-containing protein 1" [UniProtKB:Q96PM5] synonym: "Androgen receptor N-terminal-interacting protein" EXACT [UniProtKB:Q96PM5] synonym: "CH-rich-interacting match with PLAG1" EXACT [UniProtKB:Q96PM5] synonym: "hPirh2" EXACT [UniProtKB:Q96PM5] synonym: "p53-induced RING-H2 protein" EXACT [UniProtKB:Q96PM5] synonym: "RING finger protein 199" EXACT [UniProtKB:Q96PM5] synonym: "Zinc finger protein 363" EXACT [UniProtKB:Q96PM5] xref: EMBL:AAK96896.1 xref: EMBL:AAL09356.1 xref: EMBL:AAL76101.1 xref: UniProtKB:Q96PM5 xref: UniProtKB:Q96PR5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005959 ! RCHY1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007673 ! gfi1b-rchy1 physical interaction relationship: transforms_into CCO:B0041222 ! ZN363_HUMAN-Phosphoserine257 [Term] id: CCO:B0005981 name: TRI27_HUMAN def: "Zinc finger protein RFP" [UniProtKB:P14373] synonym: "Ret finger protein" EXACT [UniProtKB:P14373] synonym: "RING finger protein 76" EXACT [UniProtKB:P14373] synonym: "Tripartite motif-containing protein 27" EXACT [UniProtKB:P14373] xref: EMBL:AAA36564.1 xref: EMBL:AAG50172.1 xref: EMBL:AAG50173.1 xref: EMBL:AAH13580.1 xref: EMBL:AAH66924.1 xref: EMBL:CAB06480.2 xref: EMBL:CAI17553.1 xref: EMBL:CAI18381.1 xref: EMBL:CAI18619.1 xref: EMBL:CAI18646.1 xref: EMBL:CAI19959.1 xref: UniProtKB:P14373 xref: UniProtKB:Q5ST26 xref: UniProtKB:Q6LA73 xref: UniProtKB:Q6NXR9 xref: UniProtKB:Q9BZY6 xref: UniProtKB:Q9UJL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005828 ! TRIM27_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0007674 ! gfi1b-rfp physical interaction relationship: participates_in CCO:I0015497 ! begain-rfp physical interaction relationship: participates_in CCO:I0015649 ! magea11-rfp physical interaction relationship: participates_in CCO:I0020295 ! dnmt1-rfp physical interaction relationship: participates_in CCO:I0020323 ! fxyd6-rfp physical interaction relationship: participates_in CCO:I0020365 ! mcoln1-rfp physical interaction relationship: participates_in CCO:I0020580 ! kctd15-rfp physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002562 ! negative regulation of gene expression, epigenetic [Term] id: CCO:B0005982 name: RNF31_HUMAN def: "RING finger protein 31" [UniProtKB:Q96EP0] synonym: "Zinc in-between-RING-finger ubiquitin-associated domain protein" EXACT [UniProtKB:Q96EP0] xref: EMBL:AAH09821.3 xref: EMBL:AAH12077.1 xref: EMBL:AAH17376.3 xref: EMBL:AAP12522.1 xref: EMBL:BAA91450.1 xref: EMBL:BAB15675.1 xref: EMBL:BAB70948.1 xref: EMBL:BAB84970.1 xref: UniProtKB:Q86VI2 xref: UniProtKB:Q8TEI0 xref: UniProtKB:Q96EP0 xref: UniProtKB:Q96GB4 xref: UniProtKB:Q96NF1 xref: UniProtKB:Q9H5F1 xref: UniProtKB:Q9NWD2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005520 ! RNF31_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0007676 ! gfi1b-rnf31 physical interaction relationship: participates_in CCO:I0018959 ! atxn1-rnf31 physical interaction relationship: transforms_into CCO:B0048381 ! RNF31_HUMAN-Phosphoserine466 [Term] id: CCO:B0005984 name: TMF1_HUMAN def: "TATA element modulatory factor" [UniProtKB:P82094] synonym: "TMF" EXACT [UniProtKB:P82094] xref: EMBL:AAD54608.1 xref: UniProtKB:P82094 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005796 ! TMF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007679 ! gfi1b-tmf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014418 ! TMF1_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0014419 ! TMF1_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0071423 ! TMF1_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0071424 ! TMF1_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0071425 ! TMF1_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0071426 ! TMF1_HUMAN-Phosphoserine344 relationship: transforms_into CCO:B0071427 ! TMF1_HUMAN-Phosphotyrosine866 relationship: transforms_into CCO:B0071428 ! TMF1_HUMAN-Phosphotyrosine877 relationship: transforms_into CCO:B0071429 ! TMF1_HUMAN-Phosphoserine925 relationship: transforms_into CCO:B0071430 ! TMF1_HUMAN-Phosphothreonine929 relationship: transforms_into CCO:B0071431 ! TMF1_HUMAN-Phosphoserine933 [Term] id: CCO:B0005985 name: TRIP6_HUMAN def: "Thyroid receptor-interacting protein 6" [UniProtKB:Q15654] synonym: "OPA-interacting protein 1" EXACT [UniProtKB:Q15654] synonym: "TRIP-6" EXACT [UniProtKB:Q15654] synonym: "ZRP-1" EXACT [UniProtKB:Q15654] synonym: "Zyxin-related protein 1" EXACT [UniProtKB:Q15654] xref: EMBL:AAB62222.1 xref: EMBL:AAC41740.1 xref: EMBL:AAD03037.1 xref: EMBL:AAH02680.1 xref: EMBL:AAH04249.1 xref: EMBL:AAH04999.1 xref: EMBL:AAH21540.1 xref: EMBL:AAH28985.1 xref: EMBL:AAK21007.1 xref: EMBL:CAA05080.1 xref: UniProtKB:O15170 xref: UniProtKB:O15275 xref: UniProtKB:Q15654 xref: UniProtKB:Q9BTB2 xref: UniProtKB:Q9BUE5 xref: UniProtKB:Q9BXP3 xref: UniProtKB:Q9UNT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005835 ! TRIP6_human relationship: has_function CCO:F0001451 ! interleukin-1 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0001948 ! interleukin-1 receptor complex relationship: participates_in CCO:I0007680 ! gfi1b-trip6 physical interaction relationship: participates_in CCO:I0007693 ! gfi1b-trip6-1 physical interaction relationship: participates_in CCO:I0015036 ! hoxa9-trip6 physical interaction relationship: participates_in CCO:I0015077 ! pom121-trip6 physical interaction relationship: participates_in CCO:I0015180 ! ilf3-trip6 physical interaction relationship: participates_in CCO:I0015379 ! catsper1-trip6 physical interaction relationship: participates_in CCO:I0015388 ! nck2-trip6 physical interaction relationship: participates_in CCO:I0015690 ! ppp1r16a-trip6 physical interaction relationship: participates_in CCO:I0015717 ! aqp1-trip6 physical interaction relationship: participates_in CCO:I0015741 ! kiaa1683-trip6 physical interaction relationship: participates_in CCO:I0015765 ! q8n2x6-trip6 physical interaction relationship: participates_in CCO:I0015795 ! trip6-vcl physical interaction relationship: participates_in CCO:I0015798 ! hoxa1-trip6 physical interaction relationship: participates_in CCO:I0016161 ! atn1-trip6 physical interaction relationship: participates_in CCO:I0017601 ! atn1-trip6-1 physical interaction relationship: participates_in CCO:I0019065 ! atxn1-trip6 physical interaction relationship: participates_in CCO:I0019408 ! hoxa9-trip6-1 physical interaction relationship: participates_in CCO:P0000825 ! release of cytoplasmic sequestered NF-kappaB relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: transforms_into CCO:B0014536 ! TRIP6_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0071565 ! TRIP6_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0071566 ! TRIP6_HUMAN-Phosphoserine147 [Term] id: CCO:B0005986 name: VISL1_HUMAN def: "Visinin-like protein 1" [UniProtKB:P62760] synonym: "Hippocalcin-like protein 3" EXACT [UniProtKB:P62760] synonym: "HLP3" EXACT [UniProtKB:P62760] synonym: "VILIP" EXACT [UniProtKB:P62760] synonym: "VLP-1" EXACT [UniProtKB:P62760] xref: EMBL:AAA91295.1 xref: EMBL:AAD02174.1 xref: EMBL:AAH22012.1 xref: EMBL:BAA86891.1 xref: UniProtKB:P28677 xref: UniProtKB:P29103 xref: UniProtKB:P42323 xref: UniProtKB:P62760 xref: UniProtKB:Q9UM20 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005904 ! VSNL1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007681 ! gfi1b-vsnl1 physical interaction relationship: participates_in CCO:I0014988 ! dtx2-vsnl1 physical interaction relationship: participates_in CCO:I0019067 ! atxn1-vsnl1 physical interaction [Term] id: CCO:B0005987 name: AES_HUMAN def: "Amino-terminal enhancer of split" [UniProtKB:Q08117] synonym: "Amino enhancer of split" EXACT [UniProtKB:Q08117] synonym: "Gp130-associated protein GAM" EXACT [UniProtKB:Q08117] synonym: "GRG protein" EXACT [UniProtKB:Q08117] synonym: "Protein ESP1" EXACT [UniProtKB:Q08117] xref: EMBL:AAA16223.1 xref: EMBL:AAC35517.1 xref: EMBL:AAC72103.1 xref: EMBL:AAD00654.1 xref: EMBL:CAA51768.1 xref: UniProtKB:Q08117 xref: UniProtKB:Q12808 xref: UniProtKB:Q96TG9 xref: UniProtKB:Q9UDY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004033 ! AES_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007683 ! gfi1b-aes physical interaction relationship: participates_in CCO:I0018933 ! atn1-aes physical interaction relationship: participates_in CCO:I0020223 ! aes-med31 physical interaction relationship: participates_in CCO:I0020224 ! aes-sh3gl3 physical interaction relationship: participates_in CCO:I0020503 ! aes-ccl7 physical interaction relationship: participates_in CCO:I0020504 ! aes-gabarap physical interaction relationship: participates_in CCO:I0020505 ! aes-rpl18a physical interaction relationship: participates_in CCO:I0020666 ! sncaip-aes physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0005988 name: ATX2_HUMAN def: "Ataxin-2" [UniProtKB:Q99700] synonym: "Spinocerebellar ataxia type 2 protein" EXACT [UniProtKB:Q99700] synonym: "Trinucleotide repeat-containing gene 13 protein" EXACT [UniProtKB:Q99700] xref: EMBL:AAB19200.1 xref: EMBL:BAC87528.1 xref: EMBL:CAA69589.1 xref: UniProtKB:A6NLD4 xref: UniProtKB:Q6ZQZ7 xref: UniProtKB:Q99493 xref: UniProtKB:Q99700 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004127 ! ATXN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007684 ! gfi1b-atxn2 physical interaction relationship: participates_in CCO:I0016184 ! atxn1-atxn2 physical interaction relationship: participates_in CCO:I0016190 ! atxn1-rbpms-3 physical interaction relationship: participates_in CCO:I0017379 ! tcp1-atx2-4 physical interaction relationship: participates_in CCO:I0017380 ! lcp1-atx2-3 physical interaction relationship: participates_in CCO:I0017570 ! znrd1-atxn2 physical interaction relationship: participates_in CCO:I0017612 ! atxn2-idh3b physical interaction relationship: participates_in CCO:I0017613 ! atxn2-ncoa4 physical interaction relationship: participates_in CCO:I0017749 ! atx2-cnsa3 physical interaction relationship: participates_in CCO:I0017750 ! atx2-cnsa1-1 physical interaction relationship: participates_in CCO:I0017751 ! atx2-cnsa3-2 physical interaction relationship: participates_in CCO:I0018199 ! atx2-pabp physical interaction relationship: participates_in CCO:I0018332 ! lcp1-atx2 physical interaction relationship: participates_in CCO:I0018333 ! tcp1-atx2-1 physical interaction relationship: participates_in CCO:I0018508 ! atx2-cnsa3-1 physical interaction relationship: participates_in CCO:I0018509 ! atx2-cnsa1 physical interaction relationship: participates_in CCO:I0018521 ! cnas3-atx2 physical interaction relationship: participates_in CCO:I0018667 ! atx2-pabp-1 physical interaction relationship: participates_in CCO:I0018669 ! atx2-cnsa1-2 physical interaction relationship: participates_in CCO:I0018670 ! atx2-cnsa3-3 physical interaction relationship: participates_in CCO:I0018905 ! a2bp1-atxn2 physical interaction relationship: participates_in CCO:I0018988 ! atxn1-atxn2-1 physical interaction relationship: participates_in CCO:I0019019 ! atxn1-atxn2-2 physical interaction relationship: participates_in CCO:I0019111 ! atxn2-actn1 physical interaction relationship: participates_in CCO:I0019112 ! atxn2-actn2 physical interaction relationship: participates_in CCO:I0019113 ! atxn2-flj35171 physical interaction relationship: participates_in CCO:I0019114 ! atxn2-kiaa1279 physical interaction relationship: participates_in CCO:I0019115 ! atxn2-sh3gl3 physical interaction relationship: participates_in CCO:I0019116 ! atxn2-tdrd7 physical interaction relationship: participates_in CCO:I0019117 ! atxn2-actn1-1 physical interaction relationship: participates_in CCO:I0019118 ! atxn2-actn2-1 physical interaction relationship: participates_in CCO:I0019119 ! atxn2-bat3 physical interaction relationship: participates_in CCO:I0019120 ! atxn2-kiaa1279-1 physical interaction relationship: participates_in CCO:I0019121 ! atxn2-sh3gl2 physical interaction relationship: participates_in CCO:I0019122 ! atxn2-sh3gl3-1 physical interaction relationship: participates_in CCO:I0019264 ! atx2-pabp-2 physical interaction relationship: participates_in CCO:I0019395 ! tcp1-atx2-3 physical interaction relationship: participates_in CCO:I0019396 ! lcp1-atx2-2 physical interaction relationship: participates_in CCO:I0020449 ! atxn2-chgb physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0063663 ! ATX2_HUMAN-Phosphoserine466 relationship: transforms_into CCO:B0063664 ! ATX2_HUMAN-Phosphoserine554 relationship: transforms_into CCO:B0063665 ! ATX2_HUMAN-Phosphoserine558 relationship: transforms_into CCO:B0063666 ! ATX2_HUMAN-Phosphoserine644 relationship: transforms_into CCO:B0063667 ! ATX2_HUMAN-Phosphoserine667 relationship: transforms_into CCO:B0063668 ! ATX2_HUMAN-Phosphoserine684 relationship: transforms_into CCO:B0063669 ! ATX2_HUMAN-Phosphothreonine741 relationship: transforms_into CCO:B0063670 ! ATX2_HUMAN-Phosphoserine744 relationship: transforms_into CCO:B0063671 ! ATX2_HUMAN-Phosphothreonine771 relationship: transforms_into CCO:B0063672 ! ATX2_HUMAN-Phosphoserine772 relationship: transforms_into CCO:B0063673 ! ATX2_HUMAN-Phosphoserine776 relationship: transforms_into CCO:B0063674 ! ATX2_HUMAN-Phosphoserine784 relationship: transforms_into CCO:B0063675 ! ATX2_HUMAN-Phosphoserine828 relationship: transforms_into CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0063677 ! ATX2_HUMAN-Phosphoserine849 relationship: transforms_into CCO:B0063678 ! ATX2_HUMAN-Phosphoserine857 relationship: transforms_into CCO:B0063679 ! ATX2_HUMAN-Phosphoserine861 relationship: transforms_into CCO:B0063680 ! ATX2_HUMAN-Phosphoserine863 relationship: transforms_into CCO:B0063681 ! ATX2_HUMAN-Phosphoserine865 relationship: transforms_into CCO:B0063682 ! ATX2_HUMAN-Phosphoserine888 relationship: transforms_into CCO:B0063683 ! ATX2_HUMAN-Phosphoserine889 [Term] id: CCO:B0005989 name: FBLN5_HUMAN def: "Fibulin-5 precursor" [UniProtKB:Q9UBX5] synonym: "Dance" EXACT [UniProtKB:Q9UBX5] synonym: "Developmental arteries and neural crest EGF-like protein" EXACT [UniProtKB:Q9UBX5] synonym: "FIBL-5" EXACT [UniProtKB:Q9UBX5] synonym: "UP50" EXACT [UniProtKB:Q9UBX5] synonym: "Urine p50 protein" EXACT [UniProtKB:Q9UBX5] xref: EMBL:AAC62107.1 xref: EMBL:AAD41768.1 xref: EMBL:AAH22280.1 xref: EMBL:AAQ89257.1 xref: EMBL:CAB38568.1 xref: UniProtKB:O75966 xref: UniProtKB:Q6UWA3 xref: UniProtKB:Q9UBX5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004617 ! FBLN5_human relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0007688 ! gfi1b-fbln5 physical interaction [Term] id: CCO:B0005991 name: PSA3_HUMAN def: "Proteasome subunit alpha type-3" [UniProtKB:P25788] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P25788] synonym: "Macropain subunit C8" EXACT [UniProtKB:P25788] synonym: "Multicatalytic endopeptidase complex subunit C8" EXACT [UniProtKB:P25788] synonym: "Proteasome component C8" EXACT [UniProtKB:P25788] xref: EMBL:AAH05265.1 xref: EMBL:AAH29402.1 xref: EMBL:AAH38990.1 xref: EMBL:AAP35357.1 xref: EMBL:AAV38520.1 xref: EMBL:BAA00659.1 xref: UniProtKB:P25788 xref: UniProtKB:Q86U83 xref: UniProtKB:Q8N1D8 xref: UniProtKB:Q9BS70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005386 ! PSMA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007691 ! gfi1b-psma3 physical interaction relationship: participates_in CCO:I0008723 ! xrn2-psma3 physical interaction relationship: participates_in CCO:I0008730 ! alpha3-alpha4 physical interaction relationship: participates_in CCO:I0008731 ! alpha3-alpha2 physical interaction relationship: participates_in CCO:I0008732 ! alpha4-alpha3 physical interaction relationship: participates_in CCO:I0008753 ! beta5-alpha3 physical interaction relationship: participates_in CCO:I0008772 ! bat2-psma3 physical interaction relationship: participates_in CCO:I0008782 ! atn1-psma3 physical interaction relationship: participates_in CCO:I0008784 ! atn1-psma3-1 physical interaction relationship: participates_in CCO:I0008787 ! prnp-psma3 physical interaction relationship: participates_in CCO:I0008788 ! rere-psma3 physical interaction relationship: participates_in CCO:I0008789 ! rere-psma3-1 physical interaction relationship: participates_in CCO:I0008792 ! psma3-psma6-1 physical interaction relationship: participates_in CCO:I0008795 ! psma6-psma3 physical interaction relationship: participates_in CCO:I0008797 ! snrpf-psma3 physical interaction relationship: participates_in CCO:I0008802 ! snrpb-psma3 physical interaction relationship: participates_in CCO:I0008803 ! stx11-psma3 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0013619 ! PSA3_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0013620 ! PSA3_HUMAN-Phosphotyrosine161 relationship: transforms_into CCO:B0013621 ! PSA3_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0013622 ! PSA3_HUMAN-Phosphoserine250 [Term] id: CCO:B0005992 name: TRAF1_HUMAN def: "TNF receptor-associated factor 1" [UniProtKB:Q13077] synonym: "Epstein-Barr virus-induced protein 6" EXACT [UniProtKB:Q13077] xref: EMBL:AAA62309.1 xref: EMBL:AAH24145.1 xref: EMBL:AAV38215.1 xref: EMBL:BAC03449.1 xref: UniProtKB:Q13077 xref: UniProtKB:Q8NF13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005822 ! TRAF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007692 ! gfi1b-traf1 physical interaction relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0017087 ! traf1-bag2 physical interaction relationship: participates_in CCO:I0017088 ! traf1-hspa1l physical interaction relationship: participates_in CCO:I0017089 ! traf1-hspa8 physical interaction relationship: participates_in CCO:I0017090 ! traf1-slc25a5 physical interaction relationship: participates_in CCO:I0017091 ! traf1-hspa9b physical interaction relationship: participates_in CCO:I0017092 ! traf1-rps3 physical interaction relationship: participates_in CCO:I0017093 ! traf1-traf1 physical interaction relationship: participates_in CCO:I0017094 ! traf1-dnaja1 physical interaction relationship: participates_in CCO:I0017095 ! traf1-c1qbp physical interaction relationship: participates_in CCO:I0017096 ! traf1-ddx5 physical interaction relationship: participates_in CCO:I0017097 ! traf1-actg1 physical interaction relationship: participates_in CCO:I0017098 ! traf1-nap1l1 physical interaction relationship: participates_in CCO:I0017099 ! traf1-anp32a physical interaction relationship: participates_in CCO:I0017100 ! traf1-rcn2 physical interaction relationship: participates_in CCO:I0017101 ! traf1-hsp70_1 physical interaction relationship: participates_in CCO:I0017102 ! traf1-q96gx9 physical interaction relationship: participates_in CCO:I0017103 ! traf1-nono physical interaction relationship: participates_in CCO:I0017104 ! traf1-ppib physical interaction relationship: participates_in CCO:I0017105 ! traf1-ighg1 physical interaction relationship: participates_in CCO:I0017106 ! traf1-ddx3x physical interaction relationship: participates_in CCO:I0017107 ! traf1-sfpq physical interaction relationship: participates_in CCO:I0017108 ! traf1-hspca physical interaction relationship: participates_in CCO:I0017109 ! traf1-gapd physical interaction relationship: participates_in CCO:I0017110 ! traf1-tuba2 physical interaction relationship: participates_in CCO:I0017202 ! traf1-traf2 physical interaction relationship: participates_in CCO:I0017504 ! tnfr2-traf1 physical interaction relationship: participates_in CCO:I0017505 ! traf1-traf2-1 physical interaction relationship: participates_in CCO:I0017506 ! traf2-traf1 physical interaction relationship: participates_in CCO:I0017508 ! traf1-traf1-1 physical interaction relationship: participates_in CCO:I0018180 ! hvem-traf1 physical interaction relationship: participates_in CCO:I0019367 ! taj-traf1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0005993 name: TXD11_HUMAN def: "Thioredoxin domain-containing protein 11" [UniProtKB:Q6PKC3] synonym: "EF-hand-binding protein 1" EXACT [UniProtKB:Q6PKC3] xref: EMBL:AAD20043.1 xref: EMBL:AAH02856.1 xref: EMBL:AAH13727.1 xref: EMBL:AAH18635.1 xref: EMBL:BAB55129.1 xref: EMBL:BAB55262.1 xref: EMBL:BAC11044.1 xref: EMBL:CAG33433.1 xref: UniProtKB:O95887 xref: UniProtKB:Q6PJA6 xref: UniProtKB:Q6PKC3 xref: UniProtKB:Q8N2Q4 xref: UniProtKB:Q96K45 xref: UniProtKB:Q96K53 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005846 ! TXNDC11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007694 ! gfi1b-txndc11 physical interaction relationship: transforms_into CCO:B0041221 ! TXD11_HUMAN-Phosphoserine828 [Term] id: CCO:B0005994 name: SACS_HUMAN def: "Sacsin" [UniProtKB:Q9NZJ4] xref: EMBL:AAF31262.1 xref: EMBL:BAA34450.1 xref: EMBL:BAC03486.1 xref: EMBL:CAE45964.1 xref: EMBL:CAH18265.1 xref: EMBL:CAI13922.3 xref: EMBL:CAI13923.3 xref: UniProtKB:O94835 xref: UniProtKB:Q5T9J5 xref: UniProtKB:Q5T9J7 xref: UniProtKB:Q5T9J8 xref: UniProtKB:Q68DF5 xref: UniProtKB:Q6MZR4 xref: UniProtKB:Q8NBF9 xref: UniProtKB:Q9NZJ4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005559 ! SACS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007695 ! sacs-actn4 physical interaction relationship: participates_in CCO:I0017585 ! tsc22d4-sacs physical interaction relationship: participates_in CCO:I0017586 ! znrd1-sacs physical interaction relationship: participates_in CCO:I0019169 ! sacs-prkcabp physical interaction relationship: transforms_into CCO:B0013955 ! SACS_HUMAN-Phosphothreonine4263 relationship: transforms_into CCO:B0070289 ! SACS_HUMAN-Phosphotyrosine4333 [Term] id: CCO:B0005995 name: RASA1_HUMAN def: "Ras GTPase-activating protein 1" [UniProtKB:P20936] synonym: "GAP" EXACT [UniProtKB:P20936] synonym: "GTPase-activating protein" EXACT [UniProtKB:P20936] synonym: "p120GAP" EXACT [UniProtKB:P20936] synonym: "Ras p21 protein activator" EXACT [UniProtKB:P20936] synonym: "RasGAP" EXACT [UniProtKB:P20936] xref: EMBL:AAA35865.1 xref: EMBL:AAA52517.1 xref: EMBL:AAH33015.1 xref: UniProtKB:P20936 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005428 ! RASA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007708 ! hras-rasa1-1 direct interaction relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000508 ! negative regulation of cell-matrix adhesion relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: participates_in CCO:P0003068 ! regulation of RNA metabolic process relationship: transforms_into CCO:B0013714 ! RASA1_HUMAN-Phosphotyrosine615 [Term] id: CCO:B0005996 name: WDR57_HUMAN def: "WD repeat-containing protein 57" [UniProtKB:Q96DI7] synonym: "38 kDa-splicing factor" EXACT [UniProtKB:Q96DI7] synonym: "hPRP8BP" EXACT [UniProtKB:Q96DI7] synonym: "Prp8-binding protein" EXACT [UniProtKB:Q96DI7] synonym: "U5 snRNP-specific 40 kDa protein" EXACT [UniProtKB:Q96DI7] xref: EMBL:AAC64084.1 xref: EMBL:AAC69625.1 xref: EMBL:AAH01494.1 xref: EMBL:CAH71848.1 xref: UniProtKB:O75938 xref: UniProtKB:O95320 xref: UniProtKB:Q96DI7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005921 ! WDR57_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000284 ! snRNP U5 relationship: located_in CCO:C0000322 ! small nucleolar ribonucleoprotein complex relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0008531 ! wdr57-ddb1 physical interaction relationship: participates_in CCO:I0020284 ! ddr1-wdr57 physical interaction [Term] id: CCO:B0005997 name: WDR76_HUMAN def: "WD repeat-containing protein 76" [UniProtKB:Q9H967] xref: EMBL:AAH25247.1 xref: EMBL:AAH51855.1 xref: EMBL:ABK41114.1 xref: EMBL:BAB14369.1 xref: EMBL:BAF83622.1 xref: UniProtKB:A0MNP5 xref: UniProtKB:Q05CI4 xref: UniProtKB:Q9H967 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005927 ! WDR76_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction [Term] id: CCO:B0005998 name: WD51B_HUMAN def: "WD repeat-containing protein 51B" [UniProtKB:Q8TC44] xref: EMBL:AAH26080.1 xref: EMBL:BAC11198.1 xref: UniProtKB:Q8TC44 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005916 ! WDR51B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: transforms_into CCO:B0071834 ! WD51B_HUMAN-Phosphoserine321 [Term] id: CCO:B0005999 name: WDR61_HUMAN def: "WD repeat-containing protein 61" [UniProtKB:Q9GZS3] synonym: "Meiotic recombination REC14 protein homolog" EXACT [UniProtKB:Q9GZS3] xref: EMBL:AAG31639.1 xref: EMBL:AAH10080.1 xref: EMBL:AAP97225.1 xref: EMBL:AAP97249.1 xref: EMBL:BAB14986.1 xref: EMBL:CAG33614.1 xref: UniProtKB:Q6IA22 xref: UniProtKB:Q7Z4X4 xref: UniProtKB:Q9GZS3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005924 ! WDR61_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: transforms_into CCO:B0014676 ! WDR61_HUMAN-N-acetylthreonine2 [Term] id: CCO:B0006000 name: WDR5B_HUMAN def: "WD repeat-containing protein 5B" [UniProtKB:Q86VZ2] xref: EMBL:AAH43494.1 xref: EMBL:BAA92110.1 xref: EMBL:CAG33560.1 xref: UniProtKB:Q86VZ2 xref: UniProtKB:Q9NUL4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005922 ! WDR5B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0008533 ! wdr5b-ddb1 physical interaction relationship: participates_in CCO:I0016336 ! mll2-rbq3-1 physical interaction relationship: participates_in CCO:I0017944 ! mll2-ash2l physical interaction relationship: participates_in CCO:I0017946 ! mll2-ash2l-1 physical interaction relationship: participates_in CCO:I0018244 ! mll2-rbq3 physical interaction [Term] id: CCO:B0006001 name: RFWD2_HUMAN def: "E3 ubiquitin-protein ligase RFWD2" [UniProtKB:Q8NHY2] synonym: "Constitutive photomorphogenesis protein 1 homolog" EXACT [UniProtKB:Q8NHY2] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8NHY2] synonym: "hCOP1" EXACT [UniProtKB:Q8NHY2] synonym: "RING finger and WD repeat domain protein 2" EXACT [UniProtKB:Q8NHY2] synonym: "RING finger protein 200" EXACT [UniProtKB:Q8NHY2] xref: EMBL:AAM34692.1 xref: EMBL:AAS82851.1 xref: EMBL:BAB15239.1 xref: EMBL:DAA01050.1 xref: UniProtKB:Q6H103 xref: UniProtKB:Q8NHY2 xref: UniProtKB:Q9H6L7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005475 ! RFWD2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0007716 ! cul4b-ddb1-1 physical interaction relationship: participates_in CCO:I0008529 ! cop1-ddb1 physical interaction [Term] id: CCO:B0006002 name: TRIB1_HUMAN def: "Tribbles homolog 1" [UniProtKB:Q96RU8] synonym: "G-protein-coupled receptor-induced protein 2" EXACT [UniProtKB:Q96RU8] synonym: "GIG-2" EXACT [UniProtKB:Q96RU8] synonym: "SKIP1" EXACT [UniProtKB:Q96RU8] synonym: "TRB-1" EXACT [UniProtKB:Q96RU8] xref: EMBL:AAG35663.1 xref: EMBL:AAH63292.1 xref: EMBL:AAK58174.1 xref: EMBL:CAA04119.1 xref: EMBL:CAI46181.1 xref: UniProtKB:O15180 xref: UniProtKB:Q96RU8 xref: UniProtKB:Q9H2Y8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005832 ! TRIB1_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004668 ! mitogen-activated protein kinase kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007735 ! trib1-map2k1-1 physical interaction relationship: participates_in CCO:I0019243 ! trib1-map2k4-1 physical interaction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0001109 ! negative regulation of smooth muscle cell migration relationship: participates_in CCO:P0001486 ! negative regulation of lipopolysaccharide-mediated signaling pathway relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation [Term] id: CCO:B0006003 name: BIM_HUMAN def: "Bcl-2-like protein 11" [UniProtKB:O43521] synonym: "Bcl2-interacting mediator of cell death" EXACT [UniProtKB:O43521] xref: EMBL:AAC39593.1 xref: EMBL:AAC39594.1 xref: EMBL:AAH33694.1 xref: EMBL:AAQ62569.1 xref: EMBL:AAQ82546.1 xref: EMBL:AAQ82547.1 xref: EMBL:AAQ99148.1 xref: EMBL:AAQ99149.1 xref: EMBL:AAQ99150.1 xref: EMBL:AAR06908.1 xref: EMBL:AAY14797.1 xref: EMBL:ABI13589.1 xref: EMBL:ABI13590.1 xref: EMBL:ABI13591.1 xref: EMBL:BAB78589.1 xref: EMBL:BAB78590.1 xref: EMBL:BAB78591.1 xref: EMBL:BAB78592.1 xref: EMBL:BAB78593.1 xref: EMBL:BAB78594.1 xref: EMBL:BAF83066.1 xref: EMBL:BAF83958.1 xref: EMBL:EAW50365.1 xref: EMBL:EAW50367.1 xref: EMBL:EAW50369.1 xref: EMBL:EAW50370.1 xref: EMBL:EAW50371.1 xref: EMBL:EAW50372.1 xref: EMBL:EAW50373.1 xref: EMBL:EAW50374.1 xref: UniProtKB:A8K2W2 xref: UniProtKB:O43521 xref: UniProtKB:O43522 xref: UniProtKB:Q0MSE7 xref: UniProtKB:Q0MSE8 xref: UniProtKB:Q0MSE9 xref: UniProtKB:Q53R28 xref: UniProtKB:Q6JTU6 xref: UniProtKB:Q6T851 xref: UniProtKB:Q6TE14 xref: UniProtKB:Q6TE15 xref: UniProtKB:Q6TE16 xref: UniProtKB:Q6V402 xref: UniProtKB:Q8WYL6 xref: UniProtKB:Q8WYL7 xref: UniProtKB:Q8WYL8 xref: UniProtKB:Q8WYL9 xref: UniProtKB:Q8WYM0 xref: UniProtKB:Q8WYM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004162 ! BCL2L11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007765 ! bim-bcl2-2 direct interaction relationship: participates_in CCO:I0007884 ! bim_bcl2_human direct interaction relationship: participates_in CCO:I0015976 ! bcl2l11-ywhab-2 phosphorylation relationship: participates_in CCO:I0018495 ! bim-dncl2a-1 physical interaction relationship: participates_in CCO:I0019270 ! bim-bclw-2 direct interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: transforms_into CCO:B0063924 ! BIM_HUMAN-Phosphoserine77 [Term] id: CCO:B0006004 name: CSMD1_HUMAN def: "CUB and sushi domain-containing protein 1 precursor" [UniProtKB:Q96PZ7] synonym: "CUB and sushi multiple domains protein 1" EXACT [UniProtKB:Q96PZ7] xref: EMBL:AAG52948.1 xref: EMBL:AAK73475.2 xref: EMBL:AAQ88541.1 xref: EMBL:ABD48881.1 xref: EMBL:ABD48882.1 xref: EMBL:ABD48883.1 xref: EMBL:ABD48884.1 xref: EMBL:ABD48885.1 xref: EMBL:BAB67783.1 xref: EMBL:BAC86754.1 xref: UniProtKB:Q0H0J5 xref: UniProtKB:Q96PZ7 xref: UniProtKB:Q96QU9 xref: UniProtKB:Q96RM4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004406 ! CSMD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006005 name: LSM1_HUMAN def: "U6 snRNA-associated Sm-like protein LSm1" [UniProtKB:O15116] synonym: "Cancer-associated Sm-like" EXACT [UniProtKB:O15116] synonym: "Small nuclear ribonuclear CaSm" EXACT [UniProtKB:O15116] xref: EMBL:AAB62189.1 xref: EMBL:AAH01767.1 xref: EMBL:CAB45865.1 xref: UniProtKB:O15116 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004991 ! LSM1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0008721 ! lsm1-psmb8 physical interaction relationship: participates_in CCO:I0008722 ! lsm1-psmb5 physical interaction relationship: participates_in CCO:I0017319 ! lsm1-hspca physical interaction relationship: participates_in CCO:I0018451 ! clic1-lsm1 physical interaction [Term] id: CCO:B0006006 name: EHMT1_HUMAN def: "Histone-lysine N-methyltransferase, H3 lysine-9 specific 5" [UniProtKB:Q9H9B1] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9H9B1] synonym: "Eu-HMTase1" EXACT [UniProtKB:Q9H9B1] synonym: "Euchromatic histone-lysine N-methyltransferase 1" EXACT [UniProtKB:Q9H9B1] synonym: "G9a-like protein 1" EXACT [UniProtKB:Q9H9B1] synonym: "GLP1" EXACT [UniProtKB:Q9H9B1] synonym: "H3-K9-HMTase 5" EXACT [UniProtKB:Q9H9B1] synonym: "Histone H3-K9 methyltransferase 5" EXACT [UniProtKB:Q9H9B1] synonym: "Lysine N-methyltransferase 1D" EXACT [UniProtKB:Q9H9B1] xref: EMBL:AAH11608.2 xref: EMBL:AAM09024.1 xref: EMBL:BAB14321.1 xref: EMBL:BAB47505.2 xref: EMBL:BAB56104.1 xref: EMBL:CAD28534.1 xref: EMBL:CAH71076.1 xref: EMBL:CAH71077.1 xref: EMBL:CAI17354.1 xref: EMBL:CAI17355.1 xref: UniProtKB:B1AQ58 xref: UniProtKB:B1AQ59 xref: UniProtKB:Q8TCN7 xref: UniProtKB:Q96F53 xref: UniProtKB:Q96JF1 xref: UniProtKB:Q96KH4 xref: UniProtKB:Q9H9B1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004555 ! EHMT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: transforms_into CCO:B0011669 ! EHMT1_HUMAN-Phosphoserine466 [Term] id: CCO:B0006007 name: ARI1A_HUMAN def: "AT-rich interactive domain-containing protein 1A" [UniProtKB:O14497] synonym: "ARID domain-containing protein 1A" EXACT [UniProtKB:O14497] synonym: "B120" EXACT [UniProtKB:O14497] synonym: "BAF250" EXACT [UniProtKB:O14497] synonym: "BAF250A" EXACT [UniProtKB:O14497] synonym: "BRG1-associated factor 250" EXACT [UniProtKB:O14497] synonym: "BRG1-associated factor 250a" EXACT [UniProtKB:O14497] synonym: "hELD" EXACT [UniProtKB:O14497] synonym: "hOSA1" EXACT [UniProtKB:O14497] synonym: "Osa homolog 1" EXACT [UniProtKB:O14497] synonym: "SWI-like protein" EXACT [UniProtKB:O14497] synonym: "SWI-SNF complex protein p270" EXACT [UniProtKB:O14497] synonym: "SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1" EXACT [UniProtKB:O14497] xref: EMBL:AAF75765.1 xref: EMBL:AAG17549.2 xref: EMBL:AAG33967.1 xref: EMBL:AAK54505.1 xref: EMBL:AAN03446.1 xref: EMBL:BAA23269.1 xref: EMBL:BAA83073.1 xref: EMBL:BAD96995.1 xref: EMBL:CAI21621.1 xref: EMBL:CAI21622.1 xref: EMBL:CAI21623.1 xref: EMBL:CAI23482.1 xref: EMBL:CAI23483.1 xref: EMBL:CAI23484.1 xref: UniProtKB:O14497 xref: UniProtKB:Q53FK9 xref: UniProtKB:Q5T0W1 xref: UniProtKB:Q5T0W2 xref: UniProtKB:Q5T0W3 xref: UniProtKB:Q8NFD6 xref: UniProtKB:Q96T89 xref: UniProtKB:Q9BY33 xref: UniProtKB:Q9HBJ5 xref: UniProtKB:Q9UPZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004091 ! ARID1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007260 ! brg1-baf250a-1 physical interaction relationship: participates_in CCO:I0007756 ! brg1-baf250a-2 physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0016289 ! arid1a-smarca4- physical interaction relationship: participates_in CCO:I0017881 ! smarca4-arid1a-1 physical interaction relationship: participates_in CCO:I0017882 ! arid1a-smarca4-5 physical interaction relationship: participates_in CCO:I0017883 ! arid1a--smarca2-1 physical interaction relationship: participates_in CCO:I0018067 ! arid1a-smarca4-3 physical interaction relationship: participates_in CCO:I0018068 ! smarca2-arid1a-1 physical interaction relationship: participates_in CCO:I0018327 ! arid1a-smarca4-4 physical interaction relationship: participates_in CCO:I0018328 ! arid1a--smarca2-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002128 ! glucocorticoid receptor signaling pathway relationship: participates_in CCO:P0002770 ! chromatin-mediated maintenance of transcription relationship: transforms_into CCO:B0010596 ! ARI1A_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0010597 ! ARI1A_HUMAN-Phosphoserine604 relationship: transforms_into CCO:B0010598 ! ARI1A_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0010599 ! ARI1A_HUMAN-Phosphoserine772 relationship: transforms_into CCO:B0010600 ! ARI1A_HUMAN-Phosphoserine1755 [Term] id: CCO:B0006008 name: HNF1A_HUMAN def: "Hepatocyte nuclear factor 1-alpha" [UniProtKB:P20823] synonym: "HNF-1A" EXACT [UniProtKB:P20823] synonym: "LFB1" EXACT [UniProtKB:P20823] synonym: "Liver-specific transcription factor LF-B1" EXACT [UniProtKB:P20823] synonym: "TCF-1" EXACT [UniProtKB:P20823] synonym: "Transcription factor 1" EXACT [UniProtKB:P20823] xref: EMBL:AAA88077.1 xref: EMBL:AAC51137.1 xref: EMBL:AAI04909.1 xref: EMBL:AAI04911.1 xref: EMBL:CAB59201.1 xref: UniProtKB:P20823 xref: UniProtKB:Q2M3H2 xref: UniProtKB:Q99861 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006359 ! HNF1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0016288 ! dyrk1b-tcf1-3 phosphorylation relationship: participates_in CCO:I0018324 ! dyrk1b-dcohm-3 physical interaction relationship: participates_in CCO:I0018325 ! dyrk1b-tcf1-1 direct interaction relationship: participates_in CCO:I0018650 ! dyrk1b-tcf1-2 phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0012199 ! HNF1A_HUMAN-Phosphothreonine74 relationship: transforms_into CCO:B0066849 ! HNF1A_HUMAN-Phosphoserine247 [Term] id: CCO:B0006009 name: OSBL1_HUMAN def: "Oxysterol-binding protein-related protein 1" [UniProtKB:Q9BXW6] synonym: "ORP-1" EXACT [UniProtKB:Q9BXW6] synonym: "OSBP-related protein 1" EXACT [UniProtKB:Q9BXW6] xref: EMBL:AAG53407.2 xref: EMBL:AAK15154.1 xref: EMBL:AAL40662.1 xref: EMBL:AAL40663.1 xref: EMBL:BAA91496.1 xref: UniProtKB:Q9BXW6 xref: UniProtKB:Q9BZF5 xref: UniProtKB:Q9NW87 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005238 ! OSBPL1A_human relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: transforms_into CCO:B0013338 ! OSBL1_HUMAN-Phosphoserine499 [Term] id: CCO:B0006010 name: TNR8_HUMAN def: "Tumor necrosis factor receptor superfamily member 8 precursor" [UniProtKB:P28908] synonym: "CD30 antigen" EXACT [UniProtKB:P28908] synonym: "CD30L receptor" EXACT [UniProtKB:P28908] synonym: "KI-1 antigen" EXACT [UniProtKB:P28908] synonym: "Lymphocyte activation antigen CD30" EXACT [UniProtKB:P28908] xref: EMBL:AAA51947.1 xref: EMBL:AAD14188.1 xref: EMBL:AAR32099.1 xref: EMBL:BAA12973.1 xref: EMBL:CAC16652.1 xref: UniProtKB:P28908 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005806 ! TNFRSF8_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002099 ! positive regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002390 ! positive regulation of TRAIL biosynthetic process [Term] id: CCO:B0006011 name: TYY1_HUMAN def: "Transcriptional repressor protein YY1" [UniProtKB:P25490] synonym: "Delta transcription factor" EXACT [UniProtKB:P25490] synonym: "INO80 complex subunit S" EXACT [UniProtKB:P25490] synonym: "NF-E1" EXACT [UniProtKB:P25490] synonym: "Yin and yang 1" EXACT [UniProtKB:P25490] synonym: "YY-1" EXACT [UniProtKB:P25490] xref: EMBL:AAA59467.1 xref: EMBL:AAA59926.1 xref: EMBL:AAH37308.1 xref: EMBL:AAH65366.1 xref: EMBL:CAA78455.1 xref: UniProtKB:P25490 xref: UniProtKB:Q14935 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005851 ! YY1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0014559 ! TYY1_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0014560 ! TYY1_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0014561 ! TYY1_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0014562 ! TYY1_HUMAN-Phosphothreonine348 [Term] id: CCO:B0006012 name: 4ET_HUMAN def: "Eukaryotic translation initiation factor 4E transporter" [UniProtKB:Q9NRA8] synonym: "4E-T" EXACT [UniProtKB:Q9NRA8] synonym: "eIF4E transporter" EXACT [UniProtKB:Q9NRA8] synonym: "Eukaryotic translation initiation factor 4E nuclear import factor 1" EXACT [UniProtKB:Q9NRA8] xref: EMBL:AAF81693.1 xref: EMBL:AAH32941.1 xref: EMBL:AAH33028.1 xref: EMBL:BAB15092.1 xref: EMBL:BAC11194.1 xref: EMBL:CAG30272.1 xref: EMBL:CAI12878.1 xref: EMBL:EAW59977.1 xref: UniProtKB:B1AKL2 xref: UniProtKB:Q8NCF2 xref: UniProtKB:Q9H708 xref: UniProtKB:Q9NRA8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004004 ! EIF4ENIF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0015250 ! eif4el3-eif4enif1 physical interaction relationship: participates_in CCO:I0017976 ! eif4e-importinalpha- physical interaction relationship: participates_in CCO:I0018275 ! 4et-eif4e physical interaction relationship: participates_in CCO:I0019032 ! atxn1-eif4enif1 physical interaction relationship: participates_in CCO:I0019339 ! eif4e-4et physical interaction relationship: transforms_into CCO:B0010378 ! 4ET_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0010379 ! 4ET_HUMAN-Phosphoserine587 relationship: transforms_into CCO:B0041107 ! 4ET_HUMAN-Phosphoserine914 relationship: transforms_into CCO:B0041108 ! 4ET_HUMAN-Phosphoserine920 relationship: transforms_into CCO:B0048150 ! 4ET_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0065221 ! 4ET_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0065222 ! 4ET_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0065223 ! 4ET_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0065224 ! 4ET_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0065225 ! 4ET_HUMAN-Phosphoserine564 relationship: transforms_into CCO:B0065226 ! 4ET_HUMAN-Phosphoserine951 [Term] id: CCO:B0006013 name: DDX6_HUMAN def: "Probable ATP-dependent RNA helicase DDX6" [UniProtKB:P26196] synonym: "ATP-dependent RNA helicase p54" EXACT [UniProtKB:P26196] synonym: "DEAD box protein 6" EXACT [UniProtKB:P26196] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P26196] synonym: "Oncogene RCK" EXACT [UniProtKB:P26196] xref: EMBL:AAH65007.1 xref: EMBL:BAA04482.1 xref: UniProtKB:P26196 xref: UniProtKB:Q5D048 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004460 ! DDX6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0011486 ! DDX6_HUMAN-Phosphothreonine36 [Term] id: CCO:B0006014 name: ZN443_HUMAN def: "Zinc finger protein 443" [UniProtKB:Q9Y2A4] synonym: "Krueppel-type zinc finger protein ZK1" EXACT [UniProtKB:Q9Y2A4] xref: EMBL:AAH32753.1 xref: EMBL:BAA75543.1 xref: UniProtKB:Q9Y2A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005960 ! ZNF443_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0006015 name: E2AK3_HUMAN def: "Eukaryotic translation initiation factor 2-alpha kinase 3 precursor" [UniProtKB:Q9NZJ5] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9NZJ5] synonym: "HsPEK" EXACT [UniProtKB:Q9NZJ5] synonym: "Pancreatic eIF2-alpha kinase" EXACT [UniProtKB:Q9NZJ5] synonym: "PRKR-like endoplasmic reticulum kinase" EXACT [UniProtKB:Q9NZJ5] xref: EMBL:AAD19961.1 xref: EMBL:AAF61199.1 xref: EMBL:AAF91480.1 xref: EMBL:AAI26357.1 xref: UniProtKB:A0AVH2 xref: UniProtKB:O95846 xref: UniProtKB:Q9NZJ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004532 ! EIF2AK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0018399 ! grp94-pek-1 physical interaction [Term] id: CCO:B0006016 name: ATF7_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-7" [UniProtKB:P17544] synonym: "Activating transcription factor 7" EXACT [UniProtKB:P17544] synonym: "Transcription factor ATF-A" EXACT [UniProtKB:P17544] xref: EMBL:CAA37118.1 xref: EMBL:CAA40483.1 xref: UniProtKB:P17544 xref: UniProtKB:Q13814 xref: UniProtKB:Q9UD83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004116 ! ATF7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010643 ! ATF7_HUMAN-Phosphothreonine51 relationship: transforms_into CCO:B0010644 ! ATF7_HUMAN-Phosphothreonine53 relationship: transforms_into CCO:B0010645 ! ATF7_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0010646 ! ATF7_HUMAN-Phosphothreonine112 relationship: transforms_into CCO:B0010647 ! ATF7_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0010648 ! ATF7_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0010649 ! ATF7_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0010650 ! ATF7_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0010651 ! ATF7_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0010652 ! ATF7_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0048173 ! ATF7_HUMAN-Phosphoserine108 [Term] id: CCO:B0006017 name: SPTC2_HUMAN def: "Serine palmitoyltransferase 2" [UniProtKB:O15270] synonym: "EC 2.3.1.50" EXACT [UniProtKB:O15270] synonym: "LCB 2" EXACT [UniProtKB:O15270] synonym: "Long chain base biosynthesis protein 2" EXACT [UniProtKB:O15270] synonym: "Serine-palmitoyl-CoA transferase 2" EXACT [UniProtKB:O15270] synonym: "SPT 2" EXACT [UniProtKB:O15270] xref: EMBL:AAC50871.1 xref: EMBL:AAD09621.1 xref: EMBL:AAH05123.1 xref: EMBL:BAA25452.2 xref: EMBL:CAA69942.1 xref: UniProtKB:O15270 xref: UniProtKB:Q16685 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005668 ! SPTLC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: transforms_into CCO:B0014199 ! SPTC2_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0014200 ! SPTC2_HUMAN-Phosphotyrosine387 [Term] id: CCO:B0006018 name: SENP7_HUMAN def: "Sentrin-specific protease 7" [UniProtKB:Q9BQF6] synonym: "EC 3.4.22.-" EXACT [UniProtKB:Q9BQF6] synonym: "Sentrin/SUMO-specific protease SENP7" EXACT [UniProtKB:Q9BQF6] synonym: "SUMO-1-specific protease 2" EXACT [UniProtKB:Q9BQF6] xref: EMBL:AAG09703.1 xref: EMBL:AAL25651.1 xref: EMBL:BAB21798.1 xref: EMBL:CAB66534.1 xref: EMBL:CAD97911.1 xref: UniProtKB:Q7Z3F4 xref: UniProtKB:Q96PS5 xref: UniProtKB:Q9BQF6 xref: UniProtKB:Q9C0F6 xref: UniProtKB:Q9HBT5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005580 ! SENP7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: transforms_into CCO:B0013988 ! SENP7_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0013989 ! SENP7_HUMAN-Phosphoserine378 [Term] id: CCO:B0006019 name: LPP3_HUMAN def: "Lipid phosphate phosphohydrolase 3" [UniProtKB:O14495] synonym: "EC 3.1.3.4" EXACT [UniProtKB:O14495] synonym: "PAP-2b" EXACT [UniProtKB:O14495] synonym: "PAP2-beta" EXACT [UniProtKB:O14495] synonym: "PAP2b" EXACT [UniProtKB:O14495] synonym: "Phosphatidate phosphohydrolase type 2b" EXACT [UniProtKB:O14495] synonym: "Phosphatidic acid phosphatase 2b" EXACT [UniProtKB:O14495] synonym: "Vascular endothelial growth factor and type I collagen-inducible protein" EXACT [UniProtKB:O14495] synonym: "VCIP" EXACT [UniProtKB:O14495] xref: EMBL:AAB50222.1 xref: EMBL:AAC63433.1 xref: EMBL:AAD02271.1 xref: EMBL:AAH09196.1 xref: EMBL:AAO84481.1 xref: EMBL:BAA22594.1 xref: UniProtKB:O14495 xref: UniProtKB:Q96GW0 xref: UniProtKB:Q99782 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004986 ! PPAP2B_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001775 ! phosphatidate phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005684 ! lipid phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: transforms_into CCO:B0012705 ! LPP3_HUMAN-Phosphotyrosine110 [Term] id: CCO:B0006020 name: BC11A_HUMAN def: "B-cell lymphoma/leukemia 11A" [UniProtKB:Q9H165] synonym: "B-cell CLL/lymphoma 11A" EXACT [UniProtKB:Q9H165] synonym: "COUP-TF-interacting protein 1" EXACT [UniProtKB:Q9H165] synonym: "Ecotropic viral integration site 9 protein homolog" EXACT [UniProtKB:Q9H165] synonym: "EVI-9" EXACT [UniProtKB:Q9H165] xref: EMBL:AAG49025.1 xref: EMBL:AAH21098.1 xref: EMBL:AAO88272.1 xref: EMBL:BAA91476.1 xref: EMBL:BAB47438.1 xref: EMBL:CAC17723.1 xref: EMBL:CAC17724.1 xref: EMBL:CAC17725.1 xref: UniProtKB:Q86W14 xref: UniProtKB:Q8WU92 xref: UniProtKB:Q96JL6 xref: UniProtKB:Q9H163 xref: UniProtKB:Q9H164 xref: UniProtKB:Q9H165 xref: UniProtKB:Q9H3G9 xref: UniProtKB:Q9NWA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004145 ! BCL11A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0006021 name: IDI2_HUMAN def: "Isopentenyl-diphosphate Delta-isomerase 2" [UniProtKB:Q9BXS1] synonym: "EC 5.3.3.2" EXACT [UniProtKB:Q9BXS1] synonym: "IPP isomerase 2" EXACT [UniProtKB:Q9BXS1] synonym: "IPPI2" EXACT [UniProtKB:Q9BXS1] synonym: "Isopentenyl pyrophosphate isomerase 2" EXACT [UniProtKB:Q9BXS1] xref: EMBL:AAH17778.1 xref: EMBL:AAK29358.1 xref: EMBL:AAK49436.1 xref: EMBL:AAK49437.1 xref: EMBL:BAB71322.1 xref: UniProtKB:Q9BXS1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004850 ! IDI2_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000852 ! isopentenyl-diphosphate delta-isomerase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006022 name: PCDH9_HUMAN def: "Protocadherin-9 precursor" [UniProtKB:Q9HC56] xref: EMBL:AAF89689.2 xref: EMBL:AAI36627.1 xref: EMBL:AAI36628.1 xref: EMBL:CAD38933.1 xref: EMBL:CAD97664.1 xref: EMBL:CAH72612.1 xref: EMBL:CAH72759.1 xref: EMBL:CAI12502.1 xref: EMBL:CAM13066.1 xref: EMBL:CAM13771.1 xref: EMBL:CAM17290.1 xref: EMBL:CAM17491.1 xref: UniProtKB:A2A6U1 xref: UniProtKB:Q5VT83 xref: UniProtKB:Q7Z3U0 xref: UniProtKB:Q8N3K7 xref: UniProtKB:Q9HC56 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005276 ! PCDH9_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006023 name: T3JAM_HUMAN def: "TRAF3-interacting JNK-activating modulator" [UniProtKB:Q9Y228] synonym: "TRAF3-interacting protein 3" EXACT [UniProtKB:Q9Y228] xref: EMBL:AAI10303.1 xref: EMBL:CAB41242.1 xref: EMBL:CAI95687.1 xref: UniProtKB:Q2YDB5 xref: UniProtKB:Q4VY06 xref: UniProtKB:Q7Z706 xref: UniProtKB:Q9Y228 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005717 ! TRAF3IP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006024 name: EPHB6_HUMAN def: "Ephrin type-B receptor 6 precursor" [UniProtKB:O15197] synonym: "HEP" EXACT [UniProtKB:O15197] synonym: "Tyrosine-protein kinase-defective receptor EPH-6" EXACT [UniProtKB:O15197] xref: EMBL:AAD03058.1 xref: EMBL:AAP20939.1 xref: EMBL:BAA21560.1 xref: UniProtKB:O15197 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004576 ! EPHB6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0019823 ! sat-ephb6 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0006025 name: WDR35_HUMAN def: "WD repeat-containing protein 35" [UniProtKB:Q9P2L0] xref: EMBL:AAH36659.1 xref: EMBL:BAA92574.2 xref: UniProtKB:Q8NE11 xref: UniProtKB:Q9P2L0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005919 ! WDR35_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006026 name: RNC_HUMAN def: "Ribonuclease 3" [UniProtKB:Q9NRR4] synonym: "Drosha" EXACT [UniProtKB:Q9NRR4] synonym: "EC 3.1.26.3" EXACT [UniProtKB:Q9NRR4] synonym: "p241" EXACT [UniProtKB:Q9NRR4] synonym: "Ribonuclease III" EXACT [UniProtKB:Q9NRR4] synonym: "RNase III" EXACT [UniProtKB:Q9NRR4] xref: EMBL:AAD29637.1 xref: EMBL:AAF80558.1 xref: EMBL:AAH41162.1 xref: EMBL:AAH54003.1 xref: EMBL:BAA91511.1 xref: EMBL:CAB45133.1 xref: UniProtKB:Q7Z5V2 xref: UniProtKB:Q86YH0 xref: UniProtKB:Q9NRR4 xref: UniProtKB:Q9NW73 xref: UniProtKB:Q9Y2V9 xref: UniProtKB:Q9Y4Y0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005518 ! RNASEN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0017369 ! rnase3l-dgcr8-1 physical interaction relationship: participates_in CCO:I0018312 ! rnase3l-dgcr8-2 physical interaction relationship: participates_in CCO:I0018313 ! rnase3l-dgcr8-3 physical interaction relationship: participates_in CCO:I0018796 ! rnase3l-dgcr8-4 physical interaction relationship: participates_in CCO:P0001363 ! gene silencing by RNA relationship: transforms_into CCO:B0013908 ! RNC_HUMAN-Phosphoserine284 [Term] id: CCO:B0006027 name: ELF1_HUMAN def: "ETS-related transcription factor Elf-1" [UniProtKB:P32519] synonym: "E74-like factor 1" EXACT [UniProtKB:P32519] xref: EMBL:AAH30507.1 xref: EMBL:CAI13220.1 xref: EMBL:EAX08640.1 xref: UniProtKB:P32519 xref: UniProtKB:Q8N6F6 xref: UniProtKB:Q9UDE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004558 ! ELF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002978 ! negative regulation of T cell receptor signaling pathway relationship: transforms_into CCO:B0011670 ! ELF1_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0011671 ! ELF1_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0011672 ! ELF1_HUMAN-Phosphoserine474 relationship: transforms_into CCO:B0011673 ! ELF1_HUMAN-Phosphothreonine566 relationship: transforms_into CCO:B0064974 ! ELF1_HUMAN-Phosphoserine163 [Term] id: CCO:B0006028 name: DYH9_HUMAN def: "Dynein heavy chain 9, axonemal" [UniProtKB:Q9NYC9] synonym: "Axonemal beta dynein heavy chain 9" EXACT [UniProtKB:Q9NYC9] synonym: "Ciliary dynein heavy chain 9" EXACT [UniProtKB:Q9NYC9] xref: EMBL:AAF69004.1 xref: EMBL:BAA21573.2 xref: EMBL:CAA10561.1 xref: EMBL:CAB94756.1 xref: UniProtKB:O15064 xref: UniProtKB:O95494 xref: UniProtKB:Q9NQ28 xref: UniProtKB:Q9NYC9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004525 ! DNAH9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000422 ! axonemal dynein complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000995 ! dynein complex relationship: located_in CCO:C0001614 ! cilium axoneme relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006029 name: PANX3_HUMAN def: "Pannexin-3" [UniProtKB:Q96QZ0] xref: EMBL:AAK95655.1 xref: UniProtKB:Q96QZ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005257 ! PANX3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000473 ! gap junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006030 name: COE1_HUMAN def: "Transcription factor COE1" [UniProtKB:Q9UH73] synonym: "Early B-cell factor" EXACT [UniProtKB:Q9UH73] synonym: "O/E-1" EXACT [UniProtKB:Q9UH73] synonym: "OE-1" EXACT [UniProtKB:Q9UH73] xref: EMBL:AAF19643.1 xref: EMBL:AAH38805.1 xref: EMBL:AAH41178.1 xref: UniProtKB:Q8IW11 xref: UniProtKB:Q9UH73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004384 ! EBF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0006031 name: PRGC1_HUMAN def: "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha" [UniProtKB:Q9UBK2] synonym: "Ligand effect modulator 6" EXACT [UniProtKB:Q9UBK2] synonym: "PGC-1-alpha" EXACT [UniProtKB:Q9UBK2] synonym: "PPAR-gamma coactivator 1-alpha" EXACT [UniProtKB:Q9UBK2] synonym: "PPARGC-1-alpha" EXACT [UniProtKB:Q9UBK2] xref: EMBL:AAD51615.1 xref: EMBL:AAD56250.1 xref: EMBL:AAF18573.1 xref: EMBL:AAF19083.1 xref: UniProtKB:Q9UBK2 xref: UniProtKB:Q9UN32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005374 ! PPARGC1A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0001989 ! positive regulation of histone acetylation relationship: participates_in CCO:P0002519 ! positive regulation of gluconeogenesis relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002687 ! positive regulation of fatty acid oxidation relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0006033 name: ARNT2_HUMAN def: "Aryl hydrocarbon receptor nuclear translocator 2" [UniProtKB:Q9HBZ2] synonym: "ARNT protein 2" EXACT [UniProtKB:Q9HBZ2] xref: EMBL:AAG15310.1 xref: EMBL:AAH36099.1 xref: EMBL:BAA20766.2 xref: UniProtKB:O15024 xref: UniProtKB:Q8IYC2 xref: UniProtKB:Q9HBZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004098 ! ARNT2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001375 ! aryl hydrocarbon receptor nuclear translocator activity relationship: has_function CCO:F0003602 ! aryl hydrocarbon receptor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0019174 ! usp7-arnt2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0006034 name: JIP3_HUMAN def: "C-jun-amino-terminal kinase-interacting protein 3" [UniProtKB:Q9UPT6] synonym: "JIP-3" EXACT [UniProtKB:Q9UPT6] synonym: "JNK MAP kinase scaffold protein 3" EXACT [UniProtKB:Q9UPT6] synonym: "JNK-interacting protein 3" EXACT [UniProtKB:Q9UPT6] synonym: "Mitogen-activated protein kinase 8-interacting protein 3" EXACT [UniProtKB:Q9UPT6] xref: EMBL:AAK61290.1 xref: EMBL:BAA83018.2 xref: EMBL:BAB15727.1 xref: EMBL:CAB72318.1 xref: EMBL:CAM26364.1 xref: EMBL:CAM26394.1 xref: UniProtKB:A2A2B3 xref: UniProtKB:Q96RY4 xref: UniProtKB:Q9H4I4 xref: UniProtKB:Q9H7P1 xref: UniProtKB:Q9NUG0 xref: UniProtKB:Q9UPT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004911 ! MAPK8IP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0020230 ! arf4l-mapk8ip3 physical interaction relationship: participates_in CCO:P0002689 ! regulation of JNK cascade relationship: transforms_into CCO:B0012440 ! JIP3_HUMAN-Phosphothreonine265 relationship: transforms_into CCO:B0012441 ! JIP3_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0012442 ! JIP3_HUMAN-Phosphothreonine275 relationship: transforms_into CCO:B0012443 ! JIP3_HUMAN-Phosphothreonine286 relationship: transforms_into CCO:B0012444 ! JIP3_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0012445 ! JIP3_HUMAN-Phosphoserine585 relationship: transforms_into CCO:B0012446 ! JIP3_HUMAN-Phosphoserine676 [Term] id: CCO:B0006035 name: PR285_HUMAN def: "Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein" [UniProtKB:Q9BYK8] synonym: "ATP-dependent helicase PRIC285" EXACT [UniProtKB:Q9BYK8] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9BYK8] synonym: "PDIP1" EXACT [UniProtKB:Q9BYK8] synonym: "PPAR-alpha-interacting complex protein 285" EXACT [UniProtKB:Q9BYK8] synonym: "PPAR-gamma DBD-interacting protein 1" EXACT [UniProtKB:Q9BYK8] synonym: "PPAR-gamma DNA-binding domain-interacting protein 1" EXACT [UniProtKB:Q9BYK8] xref: EMBL:AAM74197.1 xref: EMBL:BAB21860.2 xref: EMBL:BAB70969.1 xref: EMBL:BAB84997.1 xref: EMBL:BAE46995.1 xref: EMBL:CAI95749.1 xref: UniProtKB:Q3C2G2 xref: UniProtKB:Q4VXQ1 xref: UniProtKB:Q8TEF3 xref: UniProtKB:Q96ND3 xref: UniProtKB:Q9BYK8 xref: UniProtKB:Q9C094 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005372 ! PRIC285_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0013607 ! PR285_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0048358 ! PR285_HUMAN-Phosphotyrosine1507 relationship: transforms_into CCO:B0069465 ! PR285_HUMAN-Phosphoserine1006 [Term] id: CCO:B0006036 name: ERCC5_HUMAN def: "DNA repair protein complementing XP-G cells" [UniProtKB:P28715] synonym: "DNA excision repair protein ERCC-5" EXACT [UniProtKB:P28715] synonym: "Xeroderma pigmentosum group G-complementing protein" EXACT [UniProtKB:P28715] xref: EMBL:AAC37533.1 xref: EMBL:AAF89179.1 xref: EMBL:AAH31522.1 xref: EMBL:AAN46091.1 xref: EMBL:AAP97715.1 xref: EMBL:BAA03812.1 xref: EMBL:CAA49598.1 xref: EMBL:CAA50481.1 xref: EMBL:CAI14530.1 xref: EMBL:CAI14531.1 xref: UniProtKB:A6NGT4 xref: UniProtKB:P28715 xref: UniProtKB:Q5JUS4 xref: UniProtKB:Q5JUS5 xref: UniProtKB:Q7Z2V3 xref: UniProtKB:Q8IZL6 xref: UniProtKB:Q8N1B7 xref: UniProtKB:Q9HD59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004580 ! ERCC5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0017579 ! ewsr1-ercc5 physical interaction relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0011745 ! ERCC5_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0011746 ! ERCC5_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0011747 ! ERCC5_HUMAN-Phosphothreonine338 relationship: transforms_into CCO:B0011748 ! ERCC5_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0011749 ! ERCC5_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0011750 ! ERCC5_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0011751 ! ERCC5_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0011752 ! ERCC5_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0011753 ! ERCC5_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0011754 ! ERCC5_HUMAN-Phosphoserine526 relationship: transforms_into CCO:B0011755 ! ERCC5_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0011756 ! ERCC5_HUMAN-Phosphoserine705 relationship: transforms_into CCO:B0011757 ! ERCC5_HUMAN-Phosphoserine724 [Term] id: CCO:B0006037 name: PAR12_HUMAN def: "Poly [ADP-ribose] polymerase 12" [UniProtKB:Q9H0J9] synonym: "EC 2.4.2.30" EXACT [UniProtKB:Q9H0J9] synonym: "PARP-12" EXACT [UniProtKB:Q9H0J9] synonym: "Zinc finger CCCH domain-containing protein 1" EXACT [UniProtKB:Q9H0J9] xref: EMBL:AAF66161.1 xref: EMBL:AAH81541.1 xref: EMBL:AAS00360.1 xref: EMBL:BAB15457.1 xref: EMBL:CAB66700.1 xref: EMBL:CAB70657.1 xref: UniProtKB:Q9H0J9 xref: UniProtKB:Q9H610 xref: UniProtKB:Q9NP36 xref: UniProtKB:Q9NTI3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005259 ! PARP12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: transforms_into CCO:B0069094 ! PAR12_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0069095 ! PAR12_HUMAN-Phosphoserine263 [Term] id: CCO:B0006038 name: NKRF_HUMAN def: "NF-kappa-B-repressing factor" [UniProtKB:O15226] synonym: "ITBA4 protein" EXACT [UniProtKB:O15226] synonym: "NFkB-repressing factor" EXACT [UniProtKB:O15226] synonym: "Transcription factor NRF" EXACT [UniProtKB:O15226] xref: EMBL:AAH40379.1 xref: EMBL:AAH47878.1 xref: EMBL:AAP43025.1 xref: EMBL:CAA68976.1 xref: EMBL:CAB56459.1 xref: UniProtKB:O15226 xref: UniProtKB:Q4VC41 xref: UniProtKB:Q9UJ91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005198 ! NKRF_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0006039 name: SMO_HUMAN def: "Smoothened homolog precursor" [UniProtKB:Q99835] synonym: "Gx protein" EXACT [UniProtKB:Q99835] synonym: "SMO" EXACT [UniProtKB:Q99835] xref: EMBL:AAB41788.1 xref: EMBL:AAC24863.1 xref: EMBL:AAD17202.1 xref: EMBL:AAF31757.1 xref: EMBL:AAH09989.1 xref: UniProtKB:Q99835 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005635 ! SMO_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000524 ! positive regulation of neuroblast proliferation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001210 ! smoothened signaling pathway in regulation of granule cell precursor cell proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0006040 name: OLA1_HUMAN def: "Obg-like ATPase 1" [UniProtKB:Q9NTK5] synonym: "EC 3.6.3.-" EXACT [UniProtKB:Q9NTK5] synonym: "GTP-binding protein 9" EXACT [UniProtKB:Q9NTK5] xref: EMBL:AAD44491.1 xref: EMBL:AAD44500.1 xref: EMBL:AAF71123.1 xref: EMBL:AAH12842.1 xref: EMBL:AAH13925.1 xref: EMBL:AAH29376.1 xref: EMBL:AAH91522.1 xref: EMBL:AAP97255.1 xref: EMBL:BAB55174.1 xref: EMBL:BAC11153.1 xref: EMBL:CAB66481.1 xref: UniProtKB:Q5BJD7 xref: UniProtKB:Q8NCI8 xref: UniProtKB:Q96CU1 xref: UniProtKB:Q96SV2 xref: UniProtKB:Q9NTK5 xref: UniProtKB:Q9P1D3 xref: UniProtKB:Q9UNY9 xref: UniProtKB:Q9Y6G4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005231 ! OLA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction [Term] id: CCO:B0006041 name: TBL1R_HUMAN def: "F-box-like/WD repeat-containing protein TBL1XR1" [UniProtKB:Q9BZK7] synonym: "Nuclear receptor corepressor/HDAC3 complex subunit TBLR1" EXACT [UniProtKB:Q9BZK7] synonym: "TBL1-related protein 1" EXACT [UniProtKB:Q9BZK7] synonym: "Transducin beta-like 1X-related protein 1" EXACT [UniProtKB:Q9BZK7] xref: EMBL:AAG44736.1 xref: EMBL:AAH60320.1 xref: EMBL:AAI13422.1 xref: EMBL:AAK00301.1 xref: EMBL:BAB14331.1 xref: UniProtKB:Q14DC3 xref: UniProtKB:Q9BZK7 xref: UniProtKB:Q9H2I1 xref: UniProtKB:Q9H9A1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005742 ! TBL1XR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014319 ! TBL1R_HUMAN-Phosphoserine119 [Term] id: CCO:B0006042 name: MINT_HUMAN def: "Msx2-interacting protein" [UniProtKB:Q96T58] synonym: "SMART/HDAC1-associated repressor protein" EXACT [UniProtKB:Q96T58] synonym: "SPEN homolog" EXACT [UniProtKB:Q96T58] xref: EMBL:AAK52750.1 xref: EMBL:BAA76773.1 xref: EMBL:BAA91405.1 xref: EMBL:BAB14324.1 xref: EMBL:CAB51072.1 xref: EMBL:CAH70858.1 xref: EMBL:CAI19526.1 xref: UniProtKB:Q96T58 xref: UniProtKB:Q9H9A8 xref: UniProtKB:Q9NWH5 xref: UniProtKB:Q9UQ01 xref: UniProtKB:Q9Y556 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005087 ! SPEN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0019009 ! atxn1-spen physical interaction relationship: participates_in CCO:I0019060 ! atxn1-spen-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0012917 ! MINT_HUMAN-Phosphoserine260 relationship: transforms_into CCO:B0012918 ! MINT_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0012919 ! MINT_HUMAN-Phosphothreonine266 relationship: transforms_into CCO:B0012920 ! MINT_HUMAN-Phosphoserine725 relationship: transforms_into CCO:B0012921 ! MINT_HUMAN-Phosphoserine727 relationship: transforms_into CCO:B0012922 ! MINT_HUMAN-Phosphoserine736 relationship: transforms_into CCO:B0012923 ! MINT_HUMAN-Phosphoserine740 relationship: transforms_into CCO:B0012924 ! MINT_HUMAN-Phosphoserine1261 relationship: transforms_into CCO:B0012925 ! MINT_HUMAN-Phosphoserine1268 relationship: transforms_into CCO:B0012926 ! MINT_HUMAN-Phosphoserine1278 relationship: transforms_into CCO:B0012927 ! MINT_HUMAN-Phosphoserine1283 relationship: transforms_into CCO:B0012928 ! MINT_HUMAN-Phosphoserine1380 relationship: transforms_into CCO:B0012929 ! MINT_HUMAN-Phosphoserine1382 relationship: transforms_into CCO:B0012930 ! MINT_HUMAN-Phosphothreonine1619 relationship: transforms_into CCO:B0012931 ! MINT_HUMAN-Phosphoserine1797 relationship: transforms_into CCO:B0012932 ! MINT_HUMAN-Phosphoserine1857 relationship: transforms_into CCO:B0012933 ! MINT_HUMAN-Phosphoserine2101 relationship: transforms_into CCO:B0012934 ! MINT_HUMAN-Phosphoserine2120 relationship: transforms_into CCO:B0012935 ! MINT_HUMAN-Phosphoserine2126 relationship: transforms_into CCO:B0012936 ! MINT_HUMAN-Phosphothreonine2393 relationship: transforms_into CCO:B0048320 ! MINT_HUMAN-Phosphoserine1918 relationship: transforms_into CCO:B0048321 ! MINT_HUMAN-Phosphoserine2481 relationship: transforms_into CCO:B0048322 ! MINT_HUMAN-Phosphoserine2493 relationship: transforms_into CCO:B0068188 ! MINT_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0068189 ! MINT_HUMAN-Phosphoserine1194 relationship: transforms_into CCO:B0068190 ! MINT_HUMAN-Phosphoserine1287 relationship: transforms_into CCO:B0068191 ! MINT_HUMAN-Phosphoserine1390 relationship: transforms_into CCO:B0068192 ! MINT_HUMAN-Phosphoserine1392 relationship: transforms_into CCO:B0068193 ! MINT_HUMAN-Phosphothreonine1439 relationship: transforms_into CCO:B0068194 ! MINT_HUMAN-Phosphothreonine1441 relationship: transforms_into CCO:B0068195 ! MINT_HUMAN-Phosphoserine1897 relationship: transforms_into CCO:B0068196 ! MINT_HUMAN-Phosphoserine2366 relationship: transforms_into CCO:B0068197 ! MINT_HUMAN-Phosphothreonine2938 relationship: transforms_into CCO:B0068198 ! MINT_HUMAN-Phosphothreonine2950 relationship: transforms_into CCO:B0068199 ! MINT_HUMAN-Phosphoserine3433 [Term] id: CCO:B0006044 name: CAC1A_HUMAN def: "Voltage-dependent P/Q-type calcium channel subunit alpha-1A" [UniProtKB:O00555] synonym: "BI" EXACT [UniProtKB:O00555] synonym: "Brain calcium channel I" EXACT [UniProtKB:O00555] synonym: "Calcium channel, L type, alpha-1 polypeptide isoform 4" EXACT [UniProtKB:O00555] synonym: "Voltage-gated calcium channel subunit alpha Cav2.1" EXACT [UniProtKB:O00555] xref: EMBL:AAB33068.1 xref: EMBL:AAB49674.1 xref: EMBL:AAB49675.1 xref: EMBL:AAB49676.1 xref: EMBL:AAB49677.1 xref: EMBL:AAB49678.1 xref: EMBL:AAB61612.1 xref: EMBL:AAB61613.1 xref: EMBL:AAB64179.1 xref: EMBL:AAC26839.1 xref: EMBL:CAA68172.1 xref: UniProtKB:O00555 xref: UniProtKB:P78510 xref: UniProtKB:P78511 xref: UniProtKB:Q16290 xref: UniProtKB:Q92690 xref: UniProtKB:Q99790 xref: UniProtKB:Q99791 xref: UniProtKB:Q99792 xref: UniProtKB:Q99793 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004205 ! CACNA1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: transforms_into CCO:B0010873 ! CAC1A_HUMAN-Phosphoserine750 relationship: transforms_into CCO:B0010874 ! CAC1A_HUMAN-Phosphoserine1822 relationship: transforms_into CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: transforms_into CCO:B0010876 ! CAC1A_HUMAN-Phosphotyrosine2076 relationship: transforms_into CCO:B0010877 ! CAC1A_HUMAN-Phosphoserine2269 relationship: transforms_into CCO:B0010878 ! CAC1A_HUMAN-Phosphoserine2378 [Term] id: CCO:B0006046 name: SAE1_HUMAN def: "SUMO-activating enzyme subunit 1" [UniProtKB:Q9UBE0] synonym: "Ubiquitin-like 1-activating enzyme E1A" EXACT [UniProtKB:Q9UBE0] xref: EMBL:AAD12785.2 xref: EMBL:AAD23902.2 xref: EMBL:AAD24433.1 xref: EMBL:AAF29104.1 xref: EMBL:AAH00344.1 xref: EMBL:AAH03611.1 xref: EMBL:AAH18271.1 xref: EMBL:AAP35954.1 xref: UniProtKB:O95717 xref: UniProtKB:Q9P020 xref: UniProtKB:Q9UBE0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005560 ! SAE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0017956 ! sumo1-uble1a-2 physical interaction relationship: transforms_into CCO:B0013956 ! SAE1_HUMAN-Phosphoserine185 [Term] id: CCO:B0006047 name: WNT16_HUMAN def: "Protein Wnt-16 precursor" [UniProtKB:Q9UBV4] xref: EMBL:AAD38052.1 xref: EMBL:AAD49351.1 xref: EMBL:AAI04920.1 xref: EMBL:AAI04946.1 xref: UniProtKB:Q2M3G1 xref: UniProtKB:Q9UBV4 xref: UniProtKB:Q9Y5C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005932 ! WNT16_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0006048 name: HSF4_HUMAN def: "Heat shock factor protein 4" [UniProtKB:Q9ULV5] synonym: "Heat shock transcription factor 4" EXACT [UniProtKB:Q9ULV5] synonym: "hHSF4" EXACT [UniProtKB:Q9ULV5] synonym: "HSF 4" EXACT [UniProtKB:Q9ULV5] synonym: "HSTF 4" EXACT [UniProtKB:Q9ULV5] xref: EMBL:BAA13433.1 xref: EMBL:BAA84581.1 xref: EMBL:BAA84582.1 xref: UniProtKB:Q99472 xref: UniProtKB:Q9ULV5 xref: UniProtKB:Q9ULV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004832 ! HSF4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation [Term] id: CCO:B0006049 name: PO2F3_HUMAN def: "POU domain, class 2, transcription factor 3" [UniProtKB:Q9UKI9] synonym: "Oct-11" EXACT [UniProtKB:Q9UKI9] synonym: "Octamer-binding transcription factor 11" EXACT [UniProtKB:Q9UKI9] synonym: "PLA-1 protein" EXACT [UniProtKB:Q9UKI9] synonym: "Transcription factor Skn-1" EXACT [UniProtKB:Q9UKI9] xref: EMBL:AAD55245.1 xref: EMBL:AAF00199.1 xref: EMBL:CAB45383.1 xref: UniProtKB:Q9UKI9 xref: UniProtKB:Q9UKR7 xref: UniProtKB:Q9Y504 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005352 ! POU2F3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0006050 name: UTP6_HUMAN def: "U3 small nucleolar RNA-associated protein 6 homolog" [UniProtKB:Q9NYH9] synonym: "Hepatocellular carcinoma-associated antigen 66" EXACT [UniProtKB:Q9NYH9] synonym: "Multiple hat domains protein" EXACT [UniProtKB:Q9NYH9] xref: EMBL:AAF66244.1 xref: EMBL:AAH15454.1 xref: EMBL:AAH35325.1 xref: EMBL:AAO15382.1 xref: EMBL:CAB77268.1 xref: UniProtKB:Q8IX96 xref: UniProtKB:Q96BL2 xref: UniProtKB:Q9NQ91 xref: UniProtKB:Q9NYH9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005891 ! UTP6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0015755 ! hca66-pepp2 physical interaction [Term] id: CCO:B0006051 name: JHD1A_HUMAN def: "JmjC domain-containing histone demethylation protein 1A" [UniProtKB:Q9Y2K7] synonym: "[Histone-H3]-lysine-36 demethylase 1A" EXACT [UniProtKB:Q9Y2K7] synonym: "CXXC-type zinc finger protein 8" EXACT [UniProtKB:Q9Y2K7] synonym: "EC 1.14.11.27" EXACT [UniProtKB:Q9Y2K7] synonym: "F-box and leucine-rich repeat protein 11" EXACT [UniProtKB:Q9Y2K7] synonym: "F-box protein FBL7" EXACT [UniProtKB:Q9Y2K7] synonym: "F-box protein Lilina" EXACT [UniProtKB:Q9Y2K7] synonym: "F-box/LRR-repeat protein 11" EXACT [UniProtKB:Q9Y2K7] xref: EMBL:AAD56012.1 xref: EMBL:AAH01203.1 xref: EMBL:AAH47371.1 xref: EMBL:AAH47486.1 xref: EMBL:AAH64360.1 xref: EMBL:BAA76848.2 xref: EMBL:BAB15795.1 xref: EMBL:CAH10721.1 xref: UniProtKB:Q49A21 xref: UniProtKB:Q4G0M3 xref: UniProtKB:Q69YY8 xref: UniProtKB:Q9BVH5 xref: UniProtKB:Q9H7H5 xref: UniProtKB:Q9UK66 xref: UniProtKB:Q9Y2K7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004910 ! FBXL11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0008780 ! fbox11-skp1 physical interaction relationship: participates_in CCO:I0016211 ! h3_peptide-fbxl11 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0012437 ! JHD1A_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0012438 ! JHD1A_HUMAN-Phosphothreonine534 relationship: transforms_into CCO:B0012439 ! JHD1A_HUMAN-Phosphothreonine632 relationship: transforms_into CCO:B0048291 ! JHD1A_HUMAN-Phosphothreonine550 relationship: transforms_into CCO:B0048292 ! JHD1A_HUMAN-Phosphoserine558 relationship: transforms_into CCO:B0048293 ! JHD1A_HUMAN-Phosphothreonine713 relationship: transforms_into CCO:B0048294 ! JHD1A_HUMAN-Phosphoserine718 relationship: transforms_into CCO:B0048295 ! JHD1A_HUMAN-Phosphothreonine720 relationship: transforms_into CCO:B0048296 ! JHD1A_HUMAN-Phosphoserine731 relationship: transforms_into CCO:B0048297 ! JHD1A_HUMAN-Phosphoserine739 relationship: transforms_into CCO:B0048298 ! JHD1A_HUMAN-Phosphoserine740 relationship: transforms_into CCO:B0067198 ! JHD1A_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0067199 ! JHD1A_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0067200 ! JHD1A_HUMAN-Phosphoserine692 relationship: transforms_into CCO:B0067201 ! JHD1A_HUMAN-Phosphoserine721 relationship: transforms_into CCO:B0067202 ! JHD1A_HUMAN-Phosphoserine832 relationship: transforms_into CCO:B0067203 ! JHD1A_HUMAN-Phosphothreonine844 relationship: transforms_into CCO:B0067204 ! JHD1A_HUMAN-Phosphoserine869 [Term] id: CCO:B0006052 name: MTMR6_HUMAN def: "Myotubularin-related protein 6" [UniProtKB:Q9Y217] synonym: "EC 3.1.3.-" EXACT [UniProtKB:Q9Y217] xref: EMBL:AAC78841.1 xref: EMBL:AAH40012.1 xref: EMBL:AAL01037.1 xref: EMBL:CAD89918.1 xref: EMBL:CAI39897.1 xref: UniProtKB:Q5JRG6 xref: UniProtKB:Q86TB7 xref: UniProtKB:Q86YH4 xref: UniProtKB:Q96P80 xref: UniProtKB:Q9Y217 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005133 ! MTMR6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: transforms_into CCO:B0013035 ! MTMR6_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0068319 ! MTMR6_HUMAN-Phosphoserine589 [Term] id: CCO:B0006057 name: TFE2_HUMAN def: "Transcription factor E2-alpha" [UniProtKB:P15923] synonym: "Immunoglobulin enhancer-binding factor E12/E47" EXACT [UniProtKB:P15923] synonym: "Immunoglobulin transcription factor 1" EXACT [UniProtKB:P15923] synonym: "Kappa-E2-binding factor" EXACT [UniProtKB:P15923] synonym: "TCF-3" EXACT [UniProtKB:P15923] synonym: "Transcription factor 3" EXACT [UniProtKB:P15923] synonym: "Transcription factor ITF-1" EXACT [UniProtKB:P15923] xref: EMBL:AAA36764.1 xref: EMBL:AAA52331.1 xref: EMBL:AAA56829.1 xref: EMBL:AAA56830.1 xref: EMBL:AAA61146.1 xref: EMBL:AAC27373.1 xref: EMBL:AAC41693.1 xref: EMBL:AAC99797.1 xref: EMBL:CAA36297.1 xref: UniProtKB:P15883 xref: UniProtKB:P15923 xref: UniProtKB:Q14208 xref: UniProtKB:Q14635 xref: UniProtKB:Q14636 xref: UniProtKB:Q9UPI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005771 ! TCF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005853 ! bHLH transcription factor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0018228 ! hash1-e47-1 physical interaction relationship: participates_in CCO:I0018229 ! e47-hash1-1 physical interaction relationship: participates_in CCO:I0018549 ! hash1-e47-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0006058 name: ARP8_HUMAN def: "Actin-related protein 8" [UniProtKB:Q9H981] synonym: "INO80 complex subunit N" EXACT [UniProtKB:Q9H981] xref: EMBL:BAB14352.1 xref: EMBL:BAB15402.1 xref: UniProtKB:Q9H663 xref: UniProtKB:Q9H981 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004101 ! ACTR8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007775 ! actr8-ruvbl physical interaction relationship: transforms_into CCO:B0010604 ! ARP8_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0063613 ! ARP8_HUMAN-Phosphoserine412 [Term] id: CCO:B0006060 name: DAPK3_HUMAN def: "Death-associated protein kinase 3" [UniProtKB:O43293] synonym: "DAP kinase 3" EXACT [UniProtKB:O43293] synonym: "DAP-like kinase" EXACT [UniProtKB:O43293] synonym: "Dlk" EXACT [UniProtKB:O43293] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O43293] synonym: "ZIP-kinase" EXACT [UniProtKB:O43293] xref: EMBL:AAI26431.1 xref: EMBL:AAI26433.1 xref: EMBL:BAA24955.1 xref: EMBL:BAA81746.1 xref: UniProtKB:A0AVN4 xref: UniProtKB:O43293 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004436 ! DAPK3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007783 ! dapk3-daxx-3 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0006061 name: BCL9_HUMAN def: "B-cell CLL/lymphoma 9 protein" [UniProtKB:O00512] synonym: "B-cell lymphoma 9 protein" EXACT [UniProtKB:O00512] synonym: "Bcl-9" EXACT [UniProtKB:O00512] synonym: "Protein legless homolog" EXACT [UniProtKB:O00512] xref: EMBL:CAA73942.1 xref: EMBL:CAI15198.1 xref: EMBL:EAW50932.1 xref: UniProtKB:O00512 xref: UniProtKB:Q5T489 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004154 ! BCL9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007791 ! cdc73-ctnnb1-6 physical interaction relationship: participates_in CCO:I0017372 ! tcf4-bcl9 physical interaction relationship: participates_in CCO:I0018045 ! bcl9-ctnnb1 physical interaction relationship: participates_in CCO:I0018046 ! bcl9-ctnnb1-1 physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0010774 ! BCL9_HUMAN-Phosphothreonine315 relationship: transforms_into CCO:B0010775 ! BCL9_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0010776 ! BCL9_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0010777 ! BCL9_HUMAN-Phosphoserine687 [Term] id: CCO:B0006062 name: PYGO2_HUMAN def: "Pygopus homolog 2" [UniProtKB:Q9BRQ0] xref: EMBL:AAH06132.2 xref: EMBL:AAH13725.1 xref: EMBL:AAH32099.1 xref: EMBL:AAL55782.1 xref: EMBL:AAL91371.1 xref: UniProtKB:Q8WYZ4 xref: UniProtKB:Q96CY2 xref: UniProtKB:Q9BRQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005404 ! PYGO2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007792 ! cdc73-ctnnb1-7 physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0013651 ! PYGO2_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0013652 ! PYGO2_HUMAN-Phosphothreonine302 [Term] id: CCO:B0006063 name: ST5_HUMAN def: "Suppression of tumorigenicity 5" [UniProtKB:P78524] synonym: "DENN domain-containing protein 2B" EXACT [UniProtKB:P78524] synonym: "HeLa tumor suppression 1" EXACT [UniProtKB:P78524] xref: EMBL:AAB23647.1 xref: EMBL:AAB97097.1 xref: EMBL:AAC50925.1 xref: EMBL:AAC50926.1 xref: EMBL:AAH36655.1 xref: EMBL:CAC35387.1 xref: UniProtKB:P78523 xref: UniProtKB:P78524 xref: UniProtKB:Q16492 xref: UniProtKB:Q7KYY2 xref: UniProtKB:Q7KZ12 xref: UniProtKB:Q8NE12 xref: UniProtKB:Q9BQQ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005678 ! ST5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007799 ! st5-abl1-1 physical interaction relationship: participates_in CCO:I0019298 ! st5-grb2-1 physical interaction relationship: transforms_into CCO:B0014232 ! ST5_HUMAN-Phosphoserine1011 relationship: transforms_into CCO:B0014233 ! ST5_HUMAN-Phosphoserine1013 relationship: transforms_into CCO:B0014234 ! ST5_HUMAN-Phosphoserine1015 relationship: transforms_into CCO:B0070945 ! ST5_HUMAN-Phosphoserine622 [Term] id: CCO:B0006064 name: CASC5_HUMAN def: "Protein CASC5" [UniProtKB:Q8NG31] synonym: "AF15q14" EXACT [UniProtKB:Q8NG31] synonym: "ALL1-fused gene from chromosome 15q14" EXACT [UniProtKB:Q8NG31] synonym: "Cancer susceptibility candidate gene 5 protein" EXACT [UniProtKB:Q8NG31] synonym: "Cancer/testis antigen 29" EXACT [UniProtKB:Q8NG31] synonym: "CT29" EXACT [UniProtKB:Q8NG31] synonym: "Protein D40/AF15q14" EXACT [UniProtKB:Q8NG31] xref: EMBL:AAF97513.1 xref: EMBL:AAL67803.1 xref: EMBL:AAM45143.1 xref: EMBL:BAB13396.1 xref: EMBL:BAC05691.1 xref: UniProtKB:Q8NG31 xref: UniProtKB:Q8NHE1 xref: UniProtKB:Q8WXA6 xref: UniProtKB:Q9HCK2 xref: UniProtKB:Q9NR92 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004220 ! CASC5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000177 ! acrosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007818 ! zwint_kntc2_1 physical interaction relationship: transforms_into CCO:B0010915 ! CASC5_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0010916 ! CASC5_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0010917 ! CASC5_HUMAN-Phosphoserine765 relationship: transforms_into CCO:B0010918 ! CASC5_HUMAN-Phosphoserine767 relationship: transforms_into CCO:B0010919 ! CASC5_HUMAN-Phosphoserine956 relationship: transforms_into CCO:B0010920 ! CASC5_HUMAN-Phosphoserine1039 relationship: transforms_into CCO:B0010921 ! CASC5_HUMAN-Phosphothreonine1042 relationship: transforms_into CCO:B0010922 ! CASC5_HUMAN-Phosphoserine1076 relationship: transforms_into CCO:B0010923 ! CASC5_HUMAN-Phosphoserine1773 relationship: transforms_into CCO:B0064070 ! CASC5_HUMAN-Phosphoserine1845 [Term] id: CCO:B0006066 name: CS025_HUMAN def: "UPF0449 protein C19orf25" [UniProtKB:Q9UFG5] xref: EMBL:AAH18441.1 xref: EMBL:BAC04262.1 xref: EMBL:CAB59260.2 xref: UniProtKB:Q8N9R7 xref: UniProtKB:Q8WV94 xref: UniProtKB:Q9UFG5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004400 ! C19orf25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007819 ! zw10_zwilch_1 physical interaction relationship: transforms_into CCO:B0031306 ! CS025_HUMAN-Phosphotyrosine63 [Term] id: CCO:B0006067 name: NTF2_HUMAN def: "Nuclear transport factor 2" [UniProtKB:P61970] synonym: "NTF-2" EXACT [UniProtKB:P61970] synonym: "Placental protein 15" EXACT [UniProtKB:P61970] synonym: "PP15" EXACT [UniProtKB:P61970] xref: EMBL:AAA85905.1 xref: EMBL:AAH02348.1 xref: EMBL:CAA30278.1 xref: EMBL:CAG33218.1 xref: UniProtKB:P13662 xref: UniProtKB:P61970 xref: UniProtKB:Q6IB67 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005218 ! NUTF2_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0007861 ! cdn1b-kpna3-3 physical interaction relationship: participates_in CCO:I0007862 ! cdn1b-kpna5-5 physical interaction [Term] id: CCO:B0006068 name: PKN1_HUMAN def: "Serine/threonine-protein kinase N1" [UniProtKB:Q16512] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q16512] synonym: "Protein kinase C-like 1" EXACT [UniProtKB:Q16512] synonym: "Protein kinase C-like PKN" EXACT [UniProtKB:Q16512] synonym: "Protein kinase PKN-alpha" EXACT [UniProtKB:Q16512] synonym: "Protein-kinase C-related kinase 1" EXACT [UniProtKB:Q16512] synonym: "Serine-threonine protein kinase N" EXACT [UniProtKB:Q16512] xref: EMBL:AAB33345.1 xref: EMBL:AAC50209.1 xref: EMBL:AAH40061.1 xref: EMBL:BAA05169.1 xref: UniProtKB:Q15143 xref: UniProtKB:Q16512 xref: UniProtKB:Q8IUV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005329 ! PKN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007865 ! pkn1-mapk12-1 physical interaction relationship: participates_in CCO:I0007866 ! pkn1-mapk12-2 physical interaction relationship: participates_in CCO:I0007867 ! pkn1-map2k6-2 physical interaction relationship: participates_in CCO:I0018742 ! pkn1-rhoa-1 direct interaction relationship: participates_in CCO:I0019381 ! pkn1-mapk14-1 physical interaction relationship: participates_in CCO:I0019382 ! pkn1-map2k3-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: transforms_into CCO:B0013547 ! PKN1_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0013548 ! PKN1_HUMAN-Phosphoserine562 relationship: transforms_into CCO:B0013549 ! PKN1_HUMAN-Phosphothreonine774 relationship: transforms_into CCO:B0013550 ! PKN1_HUMAN-Phosphoserine916 relationship: transforms_into CCO:B0048356 ! PKN1_HUMAN-Phosphothreonine778 relationship: transforms_into CCO:B0069363 ! PKN1_HUMAN-Phosphoserine533 relationship: transforms_into CCO:B0069364 ! PKN1_HUMAN-Phosphoserine537 relationship: transforms_into CCO:B0069365 ! PKN1_HUMAN-Phosphoserine559 [Term] id: CCO:B0006069 name: PO2F1_HUMAN def: "POU domain, class 2, transcription factor 1" [UniProtKB:P14859] synonym: "NF-A1" EXACT [UniProtKB:P14859] synonym: "Oct-1" EXACT [UniProtKB:P14859] synonym: "Octamer-binding transcription factor 1" EXACT [UniProtKB:P14859] synonym: "OTF-1" EXACT [UniProtKB:P14859] xref: EMBL:AAH01664.1 xref: EMBL:AAH03571.1 xref: EMBL:AAH07388.1 xref: EMBL:AAH52274.1 xref: EMBL:AAM77920.1 xref: EMBL:CAA31767.1 xref: EMBL:CAI15170.1 xref: EMBL:CAI15171.1 xref: UniProtKB:P14859 xref: UniProtKB:Q5TBT7 xref: UniProtKB:Q6PK46 xref: UniProtKB:Q8NEU9 xref: UniProtKB:Q9BPV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005351 ! POU2F1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007872 ! hcfc1-pou2f1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013593 ! PO2F1_HUMAN-Phosphoserine448 [Term] id: CCO:B0006070 name: EGR2_HUMAN def: "Early growth response protein 2" [UniProtKB:P11161] synonym: "AT591" EXACT [UniProtKB:P11161] synonym: "EGR-2" EXACT [UniProtKB:P11161] synonym: "Protein Krox-20" EXACT [UniProtKB:P11161] xref: EMBL:AAA52372.1 xref: EMBL:AAD24588.1 xref: EMBL:AAH35625.1 xref: EMBL:CAH18435.1 xref: EMBL:CAH73827.2 xref: UniProtKB:P11161 xref: UniProtKB:Q68CZ5 xref: UniProtKB:Q8IV26 xref: UniProtKB:Q9UNA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004554 ! EGR2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007873 ! hcfc1-egr2-1 physical interaction relationship: participates_in CCO:I0019711 ! egr2-med31 physical interaction relationship: participates_in CCO:I0020299 ! egr2-acp5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002785 ! regulation of neuronal synaptic plasticity [Term] id: CCO:B0006071 name: P3C2A_HUMAN def: "Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide" [UniProtKB:O00443] synonym: "EC 2.7.1.154" EXACT [UniProtKB:O00443] synonym: "Phosphoinositide 3-Kinase-C2-alpha" EXACT [UniProtKB:O00443] synonym: "PI3K-C2alpha" EXACT [UniProtKB:O00443] synonym: "PtdIns-3-kinase C2 alpha" EXACT [UniProtKB:O00443] xref: EMBL:AAI13659.1 xref: EMBL:CAA73797.1 xref: UniProtKB:O00443 xref: UniProtKB:Q14CQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005243 ! PIK3C2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007877 ! egfr-pik3c2a-1 physical interaction relationship: participates_in CCO:I0019389 ! erbb2-pik3c2a-1 physical interaction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 [Term] id: CCO:B0006072 name: PPIA_HUMAN def: "Peptidyl-prolyl cis-trans isomerase A" [UniProtKB:P62937] synonym: "Cyclophilin A" EXACT [UniProtKB:P62937] synonym: "Cyclosporin A-binding protein" EXACT [UniProtKB:P62937] synonym: "EC 5.2.1.8" EXACT [UniProtKB:P62937] synonym: "PPIase A" EXACT [UniProtKB:P62937] synonym: "Rotamase A" EXACT [UniProtKB:P62937] xref: EMBL:AAH00689.1 xref: EMBL:AAH03026.2 xref: EMBL:AAH05320.1 xref: EMBL:AAH05982.1 xref: EMBL:AAH07104.1 xref: EMBL:AAH13915.1 xref: EMBL:AAH73992.1 xref: EMBL:AAI06031.1 xref: EMBL:AAU13906.1 xref: EMBL:CAA37039.1 xref: EMBL:CAA68264.1 xref: EMBL:CAG32988.1 xref: UniProtKB:P05092 xref: UniProtKB:P62937 xref: UniProtKB:Q3KQW3 xref: UniProtKB:Q6IBU5 xref: UniProtKB:Q96IX3 xref: UniProtKB:Q9BRU4 xref: UniProtKB:Q9BTY9 xref: UniProtKB:Q9UC61 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005364 ! PPIA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007885 ! supt5h-ppia-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008332 ! supt5h-ppia physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: transforms_into CCO:B0013600 ! PPIA_HUMAN-N-acetylvaline2 relationship: transforms_into CCO:B0013601 ! PPIA_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0013602 ! PPIA_HUMAN-N6-acetyllysine125 relationship: transforms_into CCO:B0013603 ! PPIA_HUMAN-Phosphothreonine157 [Term] id: CCO:B0006073 name: AN32A_HUMAN def: "Acidic leucine-rich nuclear phosphoprotein 32 family member A" [UniProtKB:P39687] synonym: "Acidic nuclear phosphoprotein pp32" EXACT [UniProtKB:P39687] synonym: "Lanp" EXACT [UniProtKB:P39687] synonym: "Leucine-rich acidic nuclear protein" EXACT [UniProtKB:P39687] synonym: "Mapmodulin" EXACT [UniProtKB:P39687] synonym: "PHAPI" EXACT [UniProtKB:P39687] synonym: "Potent heat-stable protein phosphatase 2A inhibitor I1PP2A" EXACT [UniProtKB:P39687] synonym: "Putative HLA-DR-associated protein I" EXACT [UniProtKB:P39687] xref: EMBL:AAB39706.1 xref: EMBL:AAB91548.1 xref: EMBL:AAC50570.1 xref: EMBL:AAH07200.1 xref: EMBL:AAP36104.1 xref: EMBL:AAQ79832.1 xref: EMBL:BAD97000.1 xref: EMBL:CAA52981.1 xref: EMBL:EAW77824.1 xref: UniProtKB:P39687 xref: UniProtKB:Q53FK4 xref: UniProtKB:Q5J8L8 xref: UniProtKB:Q7M4N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004052 ! ANP32A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007886 ! axin1-anp32a-1 physical interaction relationship: participates_in CCO:I0008071 ! axin1-anp32a physical interaction relationship: participates_in CCO:I0017099 ! traf1-anp32a physical interaction relationship: participates_in CCO:I0019148 ! anp32a-kpna1 physical interaction relationship: participates_in CCO:I0019149 ! anp32a-kpna5 physical interaction relationship: participates_in CCO:I0019150 ! anp32a-kpna6 physical interaction relationship: participates_in CCO:I0020332 ! hspb3-anp32a physical interaction relationship: participates_in CCO:I0020610 ! nsfl1c-anp32a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0010509 ! AN32A_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0065622 ! AN32A_HUMAN-Phosphothreonine15 relationship: transforms_into CCO:B0065623 ! AN32A_HUMAN-Phosphoserine17 [Term] id: CCO:B0006074 name: DPYL1_HUMAN def: "Dihydropyrimidinase-related protein 1" [UniProtKB:Q14194] synonym: "Collapsin response mediator protein 1" EXACT [UniProtKB:Q14194] synonym: "CRMP-1" EXACT [UniProtKB:Q14194] synonym: "DRP-1" EXACT [UniProtKB:Q14194] xref: EMBL:AAA93201.1 xref: EMBL:AAH00252.1 xref: EMBL:AAH07613.1 xref: EMBL:AAK55500.1 xref: EMBL:AAP35452.1 xref: EMBL:BAA11190.1 xref: UniProtKB:Q13024 xref: UniProtKB:Q14194 xref: UniProtKB:Q96TC8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004510 ! CRMP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007887 ! axin1-crmp1 physical interaction relationship: participates_in CCO:I0007997 ! axin1-crmp1-1 physical interaction relationship: participates_in CCO:I0008237 ! smpd3-crmp1 physical interaction relationship: participates_in CCO:I0008292 ! pmf1-crmp1 physical interaction relationship: participates_in CCO:I0008370 ! cdk5rap3-crmp1 physical interaction relationship: participates_in CCO:I0016037 ! hd-crmp1 physical interaction relationship: participates_in CCO:I0018154 ! crmp1-hd physical interaction relationship: participates_in CCO:I0019542 ! rpa2-crmp1 physical interaction relationship: participates_in CCO:I0019550 ! serpinb9-crmp1 physical interaction relationship: participates_in CCO:I0019555 ! znf24-crmp1 physical interaction relationship: participates_in CCO:I0019574 ! ccl18-crmp1 physical interaction relationship: participates_in CCO:I0019576 ! cdk5rap2-crmp1 physical interaction relationship: participates_in CCO:I0019586 ! eef1d-crmp1 physical interaction relationship: participates_in CCO:I0019593 ! hspe1-crmp1 physical interaction relationship: participates_in CCO:I0019632 ! tk1-crmp1 physical interaction relationship: participates_in CCO:I0019636 ! tnfrsf6-crmp1 physical interaction relationship: participates_in CCO:I0019720 ! fth1-crmp1 physical interaction relationship: participates_in CCO:I0019723 ! fubp1-crmp1 physical interaction relationship: participates_in CCO:I0019785 ! pfn1-crmp1 physical interaction relationship: participates_in CCO:I0019848 ! tfg-crmp1 physical interaction relationship: participates_in CCO:I0020026 ! hmgb1-crmp1 physical interaction relationship: participates_in CCO:I0020408 ! ppp1r8-crmp1 physical interaction relationship: participates_in CCO:I0020444 ! rtn4-crmp1 physical interaction relationship: participates_in CCO:I0020591 ! mcm3ap-crmp1 physical interaction relationship: transforms_into CCO:B0011581 ! DPYL1_HUMAN-Phosphothreonine509 relationship: transforms_into CCO:B0031312 ! DPYL1_HUMAN-Phosphotyrosine431 relationship: transforms_into CCO:B0031313 ! DPYL1_HUMAN-Phosphotyrosine504 [Term] id: CCO:B0006076 name: CNBP1_HUMAN def: "Beta-catenin-interacting protein 1" [UniProtKB:Q9NSA3] synonym: "Inhibitor of beta-catenin and Tcf-4" EXACT [UniProtKB:Q9NSA3] xref: EMBL:AAH14300.1 xref: EMBL:BAB03458.1 xref: UniProtKB:Q9NSA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004375 ! CTNNBIP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007942 ! apc-ctnnb1-1 physical interaction relationship: participates_in CCO:I0015303 ! c1orf165-ctnnbip1 physical interaction relationship: participates_in CCO:I0015862 ! ctnnb1-ctnnbip1-6 direct interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0006077 name: EPAS1_HUMAN def: "Endothelial PAS domain-containing protein 1" [UniProtKB:Q99814] synonym: "Basic-helix-loop-helix-PAS protein MOP2" EXACT [UniProtKB:Q99814] synonym: "EPAS-1" EXACT [UniProtKB:Q99814] synonym: "HIF-1 alpha-like factor" EXACT [UniProtKB:Q99814] synonym: "HIF-2 alpha" EXACT [UniProtKB:Q99814] synonym: "HIF2 alpha" EXACT [UniProtKB:Q99814] synonym: "HLF" EXACT [UniProtKB:Q99814] synonym: "Hypoxia-inducible factor 2 alpha" EXACT [UniProtKB:Q99814] synonym: "Member of PAS protein 2" EXACT [UniProtKB:Q99814] xref: EMBL:AAB41495.1 xref: EMBL:AAC51212.1 xref: EMBL:AAH51338.1 xref: UniProtKB:Q86VA2 xref: UniProtKB:Q99630 xref: UniProtKB:Q99814 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004570 ! EPAS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007956 ! epas1-ep300-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0011715 ! EPAS1_HUMAN-4-hydroxyproline405 relationship: transforms_into CCO:B0011716 ! EPAS1_HUMAN-4-hydroxyproline531 relationship: transforms_into CCO:B0011717 ! EPAS1_HUMAN-Phosphothreonine840 relationship: transforms_into CCO:B0011718 ! EPAS1_HUMAN-3-hydroxyasparagine847 [Term] id: CCO:B0006078 name: PCNT_HUMAN def: "Pericentrin" [UniProtKB:O95613] synonym: "Kendrin" EXACT [UniProtKB:O95613] synonym: "Pericentrin B" EXACT [UniProtKB:O95613] xref: EMBL:AAD10838.1 xref: EMBL:AAP46636.1 xref: EMBL:BAA23698.3 xref: EMBL:BAC04252.1 xref: UniProtKB:O43152 xref: UniProtKB:O95613 xref: UniProtKB:Q7Z7C9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005280 ! PCNT_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:I0007970 ! disc1-tubg-1 physical interaction relationship: transforms_into CCO:B0013439 ! PCNT_HUMAN-Phosphoserine1703 [Term] id: CCO:B0006079 name: EF1G_HUMAN def: "Elongation factor 1-gamma" [UniProtKB:P26641] synonym: "eEF-1B gamma" EXACT [UniProtKB:P26641] synonym: "EF-1-gamma" EXACT [UniProtKB:P26641] xref: EMBL:AAC18414.1 xref: EMBL:AAF69604.1 xref: EMBL:AAH00384.1 xref: EMBL:AAH06509.1 xref: EMBL:AAH06520.1 xref: EMBL:AAH07949.2 xref: EMBL:AAH09865.1 xref: EMBL:AAH13918.1 xref: EMBL:AAH15813.1 xref: EMBL:AAH21974.2 xref: EMBL:AAH28179.1 xref: EMBL:AAH31012.1 xref: EMBL:AAH67738.1 xref: EMBL:CAA45089.1 xref: EMBL:CAA77630.1 xref: UniProtKB:P26641 xref: UniProtKB:Q6PJ62 xref: UniProtKB:Q6PK31 xref: UniProtKB:Q96CU2 xref: UniProtKB:Q9P196 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004547 ! EEF1G_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0007986 ! dleu1-eef1g physical interaction relationship: participates_in CCO:I0008091 ! dkc1-eef1g physical interaction relationship: participates_in CCO:I0008375 ! chfr-eef1g physical interaction relationship: participates_in CCO:I0008394 ! hdac5-eef1g physical interaction relationship: participates_in CCO:I0015443 ! eef1d-eef1g-1 physical interaction relationship: participates_in CCO:I0015491 ! eef1g-ilf2 physical interaction relationship: participates_in CCO:I0016039 ! gadd45g-eef1g physical interaction relationship: participates_in CCO:I0019524 ! eef1d-eef1g physical interaction relationship: participates_in CCO:I0019525 ! eef1g-eef1d physical interaction relationship: participates_in CCO:I0019531 ! cdc42-eef1g physical interaction relationship: participates_in CCO:I0019533 ! cdk5rap2-eef1g physical interaction relationship: participates_in CCO:I0019557 ! znf24-eef1g physical interaction relationship: participates_in CCO:I0019572 ! trib3-eef1g physical interaction relationship: participates_in CCO:I0019587 ! eef1g-med31 physical interaction relationship: participates_in CCO:I0019607 ! pdcd5-eef1g physical interaction relationship: participates_in CCO:I0019649 ! arf1-eef1g physical interaction relationship: participates_in CCO:I0019682 ! cbx8-eef1g physical interaction relationship: participates_in CCO:I0019715 ! fen1-eef1g physical interaction relationship: participates_in CCO:I0019771 ! nck2-eef1g physical interaction relationship: participates_in CCO:I0019866 ! tp53i3-eef1g physical interaction relationship: participates_in CCO:I0020274 ! centa2-eef1g physical interaction relationship: participates_in CCO:I0020559 ! flj38944-eef1g physical interaction relationship: transforms_into CCO:B0011648 ! EF1G_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0011649 ! EF1G_HUMAN-Phosphothreonine43 [Term] id: CCO:B0006081 name: CBPE_HUMAN def: "Carboxypeptidase E precursor" [UniProtKB:P16870] synonym: "Carboxypeptidase H" EXACT [UniProtKB:P16870] synonym: "CPE" EXACT [UniProtKB:P16870] synonym: "CPH" EXACT [UniProtKB:P16870] synonym: "EC 3.4.17.10" EXACT [UniProtKB:P16870] synonym: "Enkephalin convertase" EXACT [UniProtKB:P16870] synonym: "Prohormone-processing carboxypeptidase" EXACT [UniProtKB:P16870] xref: EMBL:AAH33866.1 xref: EMBL:AAH53612.1 xref: EMBL:BAA86053.1 xref: EMBL:CAA35767.1 xref: UniProtKB:P16870 xref: UniProtKB:Q9UIU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004229 ! CPE_human relationship: has_function CCO:F0000649 ! carboxypeptidase activity relationship: has_function CCO:F0000651 ! carboxypeptidase A activity relationship: has_function CCO:F0000652 ! carboxypeptidase E activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0007984 ! cpe-rif1 physical interaction relationship: participates_in CCO:I0008009 ! cpe-rpa1 physical interaction relationship: participates_in CCO:I0019534 ! cpe-med31 physical interaction relationship: participates_in CCO:I0019578 ! cpe-utp14a physical interaction relationship: participates_in CCO:I0019696 ! cpe-poldip2 physical interaction relationship: participates_in CCO:I0019954 ! cpe-chd3 physical interaction relationship: participates_in CCO:I0019955 ! cpe-gtf3c1 physical interaction relationship: participates_in CCO:I0019956 ! cpe-pola2 physical interaction relationship: participates_in CCO:I0020277 ! cpe-robo2 physical interaction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0006082 name: CHD3_HUMAN def: "Chromodomain-helicase-DNA-binding protein 3" [UniProtKB:Q12873] synonym: "ATP-dependent helicase CHD3" EXACT [UniProtKB:Q12873] synonym: "CHD-3" EXACT [UniProtKB:Q12873] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q12873] synonym: "hZFH" EXACT [UniProtKB:Q12873] synonym: "Mi-2 autoantigen 240 kDa protein" EXACT [UniProtKB:Q12873] synonym: "Mi2-alpha" EXACT [UniProtKB:Q12873] synonym: "Zinc finger helicase" EXACT [UniProtKB:Q12873] xref: EMBL:AAB87383.1 xref: EMBL:AAC39923.1 xref: EMBL:AAC50228.1 xref: UniProtKB:Q12873 xref: UniProtKB:Q9Y4I0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004344 ! CHD3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007989 ! ptn-chd3 physical interaction relationship: participates_in CCO:I0008041 ! rad51-chd3 physical interaction relationship: participates_in CCO:I0008111 ! gps2-chd3 physical interaction relationship: participates_in CCO:I0008126 ! kif15-chd3 physical interaction relationship: participates_in CCO:I0008348 ! ube1c-chd3 physical interaction relationship: participates_in CCO:I0008796 ! psme1-chd3 physical interaction relationship: participates_in CCO:I0018183 ! cgi-cdh_3 physical interaction relationship: participates_in CCO:I0018184 ! cgi-cdh_3-2 physical interaction relationship: participates_in CCO:I0018186 ! cdh_3-cgi-1 physical interaction relationship: participates_in CCO:I0018493 ! cgi-cdh_3-1 physical interaction relationship: participates_in CCO:I0019360 ! cdh_3-cgi physical interaction relationship: participates_in CCO:I0019535 ! cstf2-chd3 physical interaction relationship: participates_in CCO:I0019552 ! sumo2-chd3 physical interaction relationship: participates_in CCO:I0019568 ! bhlhb2-chd3 physical interaction relationship: participates_in CCO:I0019579 ! creb1-chd3 physical interaction relationship: participates_in CCO:I0019590 ! fubp1-chd3 physical interaction relationship: participates_in CCO:I0019623 ! sirt6-chd3 physical interaction relationship: participates_in CCO:I0019624 ! slc25a6-chd3 physical interaction relationship: participates_in CCO:I0019657 ! ars2-chd3 physical interaction relationship: participates_in CCO:I0019678 ! c2orf17-chd3 physical interaction relationship: participates_in CCO:I0019680 ! c7orf36-chd3 physical interaction relationship: participates_in CCO:I0019695 ! chd3-immt physical interaction relationship: participates_in CCO:I0019744 ! ik-chd3 physical interaction relationship: participates_in CCO:I0019758 ! luc7l2-chd3 physical interaction relationship: participates_in CCO:I0019760 ! mafg-chd3 physical interaction relationship: participates_in CCO:I0019761 ! man2a2-chd3 physical interaction relationship: participates_in CCO:I0019777 ! paics-chd3 physical interaction relationship: participates_in CCO:I0019778 ! rp11_102m16_2-chd3 physical interaction relationship: participates_in CCO:I0019816 ! rpl29-chd3 physical interaction relationship: participates_in CCO:I0019819 ! safb-chd3 physical interaction relationship: participates_in CCO:I0019868 ! trim28-chd3 physical interaction relationship: participates_in CCO:I0019869 ! ttr-chd3 physical interaction relationship: participates_in CCO:I0019939 ! casp8-chd3 physical interaction relationship: participates_in CCO:I0019954 ! cpe-chd3 physical interaction relationship: participates_in CCO:I0019968 ! c4orf17-chd3 physical interaction relationship: participates_in CCO:I0019988 ! ems1-chd3 physical interaction relationship: participates_in CCO:I0020089 ! nif3l1bp1-chd3 physical interaction relationship: participates_in CCO:I0020128 ! prg2-chd3 physical interaction relationship: participates_in CCO:I0020132 ! ptprs-chd3 physical interaction relationship: participates_in CCO:I0020162 ! sat-chd3 physical interaction relationship: participates_in CCO:I0020201 ! tnfrsf14-chd3 physical interaction relationship: participates_in CCO:I0020216 ! xrcc4-chd3 physical interaction relationship: participates_in CCO:I0020222 ! adh5-chd3 physical interaction relationship: participates_in CCO:I0020254 ! atpif1-chd3 physical interaction relationship: participates_in CCO:I0020268 ! casp6-chd3 physical interaction relationship: participates_in CCO:I0020292 ! dkfzp434d1428-chd3 physical interaction relationship: participates_in CCO:I0020309 ! fbp2-chd3 physical interaction relationship: participates_in CCO:I0020336 ! hsph1-chd3 physical interaction relationship: participates_in CCO:I0020396 ! pcmt1-chd3 physical interaction relationship: participates_in CCO:I0020451 ! serf2-chd3 physical interaction relationship: participates_in CCO:I0020481 ! tm4sf6-chd3 physical interaction relationship: participates_in CCO:I0020501 ! actr1b-chd3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0011200 ! CHD3_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0011201 ! CHD3_HUMAN-Phosphoserine713 relationship: transforms_into CCO:B0011202 ! CHD3_HUMAN-Phosphoserine1601 relationship: transforms_into CCO:B0011203 ! CHD3_HUMAN-Phosphoserine1605 relationship: transforms_into CCO:B0035992 ! CHD3_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0064303 ! CHD3_HUMAN-Phosphoserine1361 relationship: transforms_into CCO:B0064304 ! CHD3_HUMAN-Phosphoserine1364 relationship: transforms_into CCO:B0064305 ! CHD3_HUMAN-Phosphoserine1367 [Term] id: CCO:B0006083 name: SBP1_HUMAN def: "Selenium-binding protein 1" [UniProtKB:Q13228] synonym: "56 kDa selenium-binding protein" EXACT [UniProtKB:Q13228] synonym: "SP56" EXACT [UniProtKB:Q13228] xref: EMBL:AAB02395.1 xref: EMBL:AAH09084.1 xref: EMBL:CAG33133.1 xref: EMBL:CAH70328.1 xref: EMBL:EAW53443.1 xref: UniProtKB:A6NML9 xref: UniProtKB:Q13228 xref: UniProtKB:Q96GX7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005568 ! SELENBP1_human relationship: has_function CCO:F0001897 ! selenium binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007991 ! selenbp1-rif1 physical interaction relationship: participates_in CCO:I0008049 ! selenbp1-rpa1 physical interaction relationship: participates_in CCO:I0019549 ! selenbp1-med31 physical interaction relationship: transforms_into CCO:B0013965 ! SBP1_HUMAN-Phosphoserine467 [Term] id: CCO:B0006084 name: SGTA_HUMAN def: "Small glutamine-rich tetratricopeptide repeat-containing protein alpha" [UniProtKB:O43765] synonym: "Alpha-SGT" EXACT [UniProtKB:O43765] synonym: "UBP" EXACT [UniProtKB:O43765] synonym: "Vpu-binding protein" EXACT [UniProtKB:O43765] xref: EMBL:AAD13117.1 xref: EMBL:AAH00390.1 xref: EMBL:AAH02989.2 xref: EMBL:AAH05165.1 xref: EMBL:AAH08885.1 xref: EMBL:AAL01051.1 xref: EMBL:CAA11565.1 xref: EMBL:CAB39725.1 xref: EMBL:CAB43297.2 xref: UniProtKB:O43765 xref: UniProtKB:Q9BTZ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005604 ! SGTA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007992 ! sgta-ptn physical interaction relationship: participates_in CCO:I0015408 ! nme3-sgta physical interaction relationship: participates_in CCO:I0019622 ! sgta-pfn2 physical interaction relationship: transforms_into CCO:B0014045 ! SGTA_HUMAN-Phosphothreonine81 relationship: transforms_into CCO:B0014046 ! SGTA_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0014047 ! SGTA_HUMAN-Phosphothreonine303 relationship: transforms_into CCO:B0014048 ! SGTA_HUMAN-Phosphoserine305 [Term] id: CCO:B0006085 name: ZNF24_HUMAN def: "Zinc finger protein 24" [UniProtKB:P17028] synonym: "Retinoic acid suppression protein A" EXACT [UniProtKB:P17028] synonym: "RSG-A" EXACT [UniProtKB:P17028] synonym: "Zinc finger and SCAN domain-containing protein 3" EXACT [UniProtKB:P17028] synonym: "Zinc finger protein 191" EXACT [UniProtKB:P17028] synonym: "Zinc finger protein KOX17" EXACT [UniProtKB:P17028] xref: EMBL:AAB37275.1 xref: EMBL:AAB70216.1 xref: EMBL:AAD19827.1 xref: EMBL:AAH03566.1 xref: EMBL:AAH16801.1 xref: EMBL:CAA36574.1 xref: UniProtKB:O14754 xref: UniProtKB:P17028 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005968 ! ZNF24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007993 ! znf24-tp53 physical interaction relationship: participates_in CCO:I0008062 ! znf24-rif1 physical interaction relationship: participates_in CCO:I0015418 ! znf24-znf446 physical interaction relationship: participates_in CCO:I0015554 ! znf24-znf434 physical interaction relationship: participates_in CCO:I0015723 ! scand1-znf24 physical interaction relationship: participates_in CCO:I0018840 ! aplp1-znf24-1 physical interaction relationship: participates_in CCO:I0019555 ! znf24-crmp1 physical interaction relationship: participates_in CCO:I0019556 ! znf24-eef1a1 physical interaction relationship: participates_in CCO:I0019557 ! znf24-eef1g physical interaction relationship: participates_in CCO:I0019639 ! znf24-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019640 ! znf24-htatip physical interaction relationship: participates_in CCO:I0019641 ! znf24-kiaa1377 physical interaction relationship: participates_in CCO:I0019642 ! znf24-unc119 physical interaction relationship: participates_in CCO:I0019881 ! znf24-aplp1 physical interaction relationship: participates_in CCO:I0019882 ! znf24-c14orf1 physical interaction relationship: participates_in CCO:I0019883 ! znf24-cops6 physical interaction relationship: participates_in CCO:I0019884 ! znf24-hap1 physical interaction relationship: participates_in CCO:I0019885 ! znf24-utp14a physical interaction relationship: participates_in CCO:I0019886 ! znf24-setdb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0014746 ! ZNF24_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0014747 ! ZNF24_HUMAN-Phosphotyrosine279 relationship: transforms_into CCO:B0014748 ! ZNF24_HUMAN-Phosphotyrosine335 [Term] id: CCO:B0006086 name: ASCC2_HUMAN def: "Activating signal cointegrator 1 complex subunit 2" [UniProtKB:Q9H1I8] synonym: "ASC-1 complex subunit p100" EXACT [UniProtKB:Q9H1I8] synonym: "Trip4 complex subunit p100" EXACT [UniProtKB:Q9H1I8] xref: EMBL:AAG45475.1 xref: EMBL:AAH25368.1 xref: EMBL:BAB14293.1 xref: EMBL:BAB15089.1 xref: EMBL:CAI95602.1 xref: UniProtKB:Q4TT54 xref: UniProtKB:Q8TAZ0 xref: UniProtKB:Q9H1I8 xref: UniProtKB:Q9H711 xref: UniProtKB:Q9H9D6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004104 ! ASCC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007996 ! ascc2-rpa1 physical interaction relationship: participates_in CCO:I0019527 ! ascc2-eef1d physical interaction relationship: participates_in CCO:I0019528 ! ascc2-rplp1 physical interaction relationship: participates_in CCO:I0019529 ! ascc2-snw1 physical interaction relationship: participates_in CCO:I0019564 ! ascc2-med31 physical interaction relationship: participates_in CCO:I0019659 ! ascc2-aof2 physical interaction relationship: participates_in CCO:I0019660 ! ascc2-ass physical interaction relationship: participates_in CCO:I0019661 ! ascc2-fbp1 physical interaction relationship: participates_in CCO:I0019662 ! ascc2-pola2 physical interaction relationship: participates_in CCO:I0019663 ! ascc2-ptd004 physical interaction relationship: participates_in CCO:I0019902 ! ascc2-c9orf74 physical interaction relationship: participates_in CCO:I0019903 ! ascc2-flj10324 physical interaction relationship: participates_in CCO:I0019904 ! ascc2-gtf3c1 physical interaction relationship: participates_in CCO:I0019905 ! ascc2-fundc2 physical interaction relationship: participates_in CCO:I0019906 ! ascc2-immt physical interaction relationship: participates_in CCO:I0019907 ! ascc2-myh9 physical interaction relationship: participates_in CCO:I0019908 ! ascc2-pin4 physical interaction relationship: participates_in CCO:I0019909 ! ascc2-pja1 physical interaction relationship: participates_in CCO:I0019910 ! ascc2-poldip2 physical interaction relationship: participates_in CCO:I0019911 ! ascc2-snrpb physical interaction relationship: participates_in CCO:I0019912 ! ascc2-tbc1d17 physical interaction relationship: participates_in CCO:I0020241 ! ascc2-cutc physical interaction relationship: participates_in CCO:I0020242 ! ascc2-ckap4 physical interaction relationship: participates_in CCO:I0020243 ! ascc2-deaf1 physical interaction relationship: participates_in CCO:I0020244 ! ascc2-elac2 physical interaction relationship: participates_in CCO:I0020245 ! ascc2-faf1 physical interaction relationship: participates_in CCO:I0020246 ! ascc2-gfer physical interaction relationship: participates_in CCO:I0020247 ! ascc2-igsf9 physical interaction relationship: participates_in CCO:I0020248 ! ascc2-lpl physical interaction relationship: participates_in CCO:I0020249 ! ascc2-ns physical interaction relationship: participates_in CCO:I0020250 ! ascc2-pik3cd physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0010606 ! ASCC2_HUMAN-Phosphoserine713 [Term] id: CCO:B0006087 name: CCL18_HUMAN def: "C-C motif chemokine 18 precursor" [UniProtKB:P55774] synonym: "Alternative macrophage activation-associated CC chemokine 1" EXACT [UniProtKB:P55774] synonym: "AMAC-1" EXACT [UniProtKB:P55774] synonym: "CC chemokine PARC" EXACT [UniProtKB:P55774] synonym: "DC-CK1" EXACT [UniProtKB:P55774] synonym: "Dendritic cell chemokine 1" EXACT [UniProtKB:P55774] synonym: "Macrophage inflammatory protein 4" EXACT [UniProtKB:P55774] synonym: "MIP-4" EXACT [UniProtKB:P55774] synonym: "Pulmonary and activation-regulated chemokine" EXACT [UniProtKB:P55774] synonym: "Small-inducible cytokine A18" EXACT [UniProtKB:P55774] xref: EMBL:AAC32287.1 xref: EMBL:AAD30390.1 xref: EMBL:AAH69700.1 xref: EMBL:AAH96124.1 xref: EMBL:AAH96125.1 xref: EMBL:AAH96126.1 xref: EMBL:AAH96127.1 xref: EMBL:BAA21670.1 xref: EMBL:BAA34368.1 xref: EMBL:CAA74039.1 xref: EMBL:CAG28588.1 xref: UniProtKB:P55774 xref: UniProtKB:Q53X71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004241 ! CCL18_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0008000 ! ccl18-tp53 physical interaction relationship: participates_in CCO:I0019530 ! ccl18-eef1a1 physical interaction relationship: participates_in CCO:I0019574 ! ccl18-crmp1 physical interaction relationship: participates_in CCO:I0019575 ! ccl18-unc119 physical interaction relationship: participates_in CCO:I0019686 ! ccl18-tle1 physical interaction relationship: participates_in CCO:I0019942 ! ccl18-c14orf1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006088 name: CPNS1_HUMAN def: "Calpain small subunit 1" [UniProtKB:P04632] synonym: "Calcium-activated neutral proteinase small subunit" EXACT [UniProtKB:P04632] synonym: "Calcium-dependent protease small subunit" EXACT [UniProtKB:P04632] synonym: "Calcium-dependent protease small subunit 1" EXACT [UniProtKB:P04632] synonym: "Calpain regulatory subunit" EXACT [UniProtKB:P04632] synonym: "CANP small subunit" EXACT [UniProtKB:P04632] synonym: "CDPS" EXACT [UniProtKB:P04632] synonym: "CSS1" EXACT [UniProtKB:P04632] xref: EMBL:AAA35646.1 xref: EMBL:AAB51183.1 xref: EMBL:AAB81546.1 xref: EMBL:AAH00592.1 xref: EMBL:AAH07779.1 xref: EMBL:AAH11903.1 xref: EMBL:AAH17308.1 xref: EMBL:AAH18931.1 xref: EMBL:AAH21933.1 xref: EMBL:AAH23643.1 xref: EMBL:AAH64998.1 xref: EMBL:AAP88777.1 xref: EMBL:AAV40829.1 xref: EMBL:CAA27726.1 xref: UniProtKB:P04632 xref: UniProtKB:Q8WTX3 xref: UniProtKB:Q96EW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004391 ! CAPNS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0008004 ! cdk4-capns1 physical interaction relationship: participates_in CCO:I0008437 ! terf1-capns1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0018743 ! capn2-capns1-1 direct interaction relationship: participates_in CCO:I0018744 ! capn2-capns1-2 direct interaction relationship: participates_in CCO:I0019934 ! c7orf20-capns1 physical interaction relationship: participates_in CCO:I0020011 ! gnb2-capns1 physical interaction relationship: participates_in CCO:I0020238 ! arr3-capns1 physical interaction relationship: participates_in CCO:I0020252 ! atp5j2-capns1 physical interaction relationship: participates_in CCO:I0020297 ! drg1-capns1 physical interaction relationship: participates_in CCO:I0020420 ! rab1a-capns1 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0011338 ! CPNS1_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0006089 name: COX17_HUMAN def: "Cytochrome c oxidase copper chaperone" [UniProtKB:Q14061] xref: EMBL:AAA98114.1 xref: EMBL:AAF82569.1 xref: EMBL:AAH10933.1 xref: EMBL:AAI05281.1 xref: EMBL:AAI08318.1 xref: UniProtKB:Q14061 xref: UniProtKB:Q3MHD6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004386 ! COX17_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0003200 ! copper chaperone activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000341 ! mitochondrial intermembrane space relationship: participates_in CCO:I0008008 ! cox17-rif1 physical interaction relationship: participates_in CCO:I0008089 ! cox17-tp53 physical interaction relationship: participates_in CCO:I0008377 ! cox17-ppbp physical interaction [Term] id: CCO:B0006090 name: IF2B_HUMAN def: "Eukaryotic translation initiation factor 2 subunit 2" [UniProtKB:P20042] synonym: "eIF-2-beta" EXACT [UniProtKB:P20042] synonym: "Eukaryotic translation initiation factor 2 subunit beta" EXACT [UniProtKB:P20042] xref: EMBL:AAA52383.1 xref: EMBL:AAH00461.1 xref: EMBL:AAH00934.1 xref: EMBL:CAB43741.1 xref: UniProtKB:P20042 xref: UniProtKB:Q9BVU0 xref: UniProtKB:Q9UJE4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004851 ! EIF2S2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008010 ! eif2s2-tp53 physical interaction relationship: participates_in CCO:I0019588 ! eif2s2-tle1 physical interaction relationship: participates_in CCO:I0019712 ! eif2s2-aplp1 physical interaction relationship: transforms_into CCO:B0012302 ! IF2B_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0012303 ! IF2B_HUMAN-Phosphoserine67 [Term] id: CCO:B0006092 name: CH10_HUMAN def: "10 kDa heat shock protein, mitochondrial" [UniProtKB:P61604] synonym: "10 kDa chaperonin" EXACT [UniProtKB:P61604] synonym: "CPN10" EXACT [UniProtKB:P61604] synonym: "Early-pregnancy factor" EXACT [UniProtKB:P61604] synonym: "EPF" EXACT [UniProtKB:P61604] synonym: "Hsp10" EXACT [UniProtKB:P61604] xref: EMBL:AAA50953.1 xref: EMBL:AAC95387.1 xref: EMBL:AAH23518.1 xref: EMBL:CAA53455.1 xref: EMBL:CAB75425.1 xref: UniProtKB:O95421 xref: UniProtKB:P61604 xref: UniProtKB:Q04984 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004342 ! HSPE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008015 ! hspe1-rif1 physical interaction relationship: participates_in CCO:I0019537 ! hspe1-c14orf1 physical interaction relationship: participates_in CCO:I0019538 ! hspe1-eef1a1 physical interaction relationship: participates_in CCO:I0019593 ! hspe1-crmp1 physical interaction relationship: participates_in CCO:I0019594 ! hspe1-tle1 physical interaction relationship: participates_in CCO:I0019595 ! hspe1-unc119 physical interaction relationship: participates_in CCO:I0019615 ! sat-hspe1 physical interaction relationship: participates_in CCO:I0019741 ! hspe1-aplp1 physical interaction relationship: participates_in CCO:I0019742 ! hspe1-zhx1 physical interaction relationship: participates_in CCO:I0020037 ! hspe1-gbp2 physical interaction relationship: participates_in CCO:P0000673 ! caspase activation relationship: transforms_into CCO:B0011196 ! CH10_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064302 ! CH10_HUMAN-Phosphotyrosine88 [Term] id: CCO:B0006093 name: LAMA4_HUMAN def: "Laminin subunit alpha-4 precursor" [UniProtKB:Q16363] xref: EMBL:AAB34635.1 xref: EMBL:BAE06109.1 xref: EMBL:CAA50261.1 xref: EMBL:CAA54258.1 xref: EMBL:CAA62596.1 xref: EMBL:CAA74636.1 xref: EMBL:CAI12950.1 xref: EMBL:CAI42325.1 xref: UniProtKB:Q14731 xref: UniProtKB:Q14735 xref: UniProtKB:Q15335 xref: UniProtKB:Q16363 xref: UniProtKB:Q4LE44 xref: UniProtKB:Q5SZG8 xref: UniProtKB:Q9UE18 xref: UniProtKB:Q9UJN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004968 ! LAMA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008017 ! lama4-rif1 physical interaction relationship: participates_in CCO:I0008018 ! lama4-tp53 physical interaction relationship: participates_in CCO:I0008128 ! lama4-ptn physical interaction relationship: participates_in CCO:I0019539 ! lama4-eef1a1 physical interaction relationship: participates_in CCO:I0019598 ! lama4-med31 physical interaction relationship: participates_in CCO:I0019599 ! lama4-unc119 physical interaction relationship: participates_in CCO:I0019754 ! lama4-cops6 physical interaction relationship: participates_in CCO:I0019755 ! lama4-ubr1 physical interaction relationship: participates_in CCO:I0019756 ! lama4-zhx1 physical interaction relationship: participates_in CCO:I0020052 ! lama4-sumo2 physical interaction relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: transforms_into CCO:B0012658 ! LAMA4_HUMAN-Phosphotyrosine1593 [Term] id: CCO:B0006094 name: Q96BK8_HUMAN def: "C8orf30A protein" [UniProtKB:Q96BK8] xref: EMBL:AAH15471.1 xref: UniProtKB:Q96BK8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006036 ! C8orf30A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008019 ! loc51236-ptn physical interaction relationship: participates_in CCO:I0008020 ! loc51236-rpa1 physical interaction relationship: participates_in CCO:I0019600 ! loc51236-med31 physical interaction relationship: participates_in CCO:I0020053 ! loc51236-pola2 physical interaction [Term] id: CCO:B0006095 name: RT12_HUMAN def: "28S ribosomal protein S12, mitochondrial precursor" [UniProtKB:O15235] synonym: "MRP-S12" EXACT [UniProtKB:O15235] synonym: "MT-RPS12" EXACT [UniProtKB:O15235] synonym: "S12mt" EXACT [UniProtKB:O15235] xref: EMBL:AAC64704.1 xref: EMBL:AAH01617.1 xref: EMBL:AAH06424.1 xref: EMBL:AAH07499.1 xref: EMBL:CAA72377.1 xref: UniProtKB:O15235 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005545 ! MRPS12_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000344 ! mitochondrial ribosome relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008024 ! mrps12-rif1 physical interaction [Term] id: CCO:B0006096 name: NACA_HUMAN def: "Nascent polypeptide-associated complex subunit alpha" [UniProtKB:Q13765] synonym: "Allergen Hom s 2" EXACT [UniProtKB:Q13765] synonym: "Alpha-NAC" EXACT [UniProtKB:Q13765] synonym: "NAC-alpha" EXACT [UniProtKB:Q13765] xref: EMBL:AAC99403.1 xref: EMBL:AAI05121.1 xref: EMBL:AAI05123.1 xref: EMBL:AAI06042.1 xref: EMBL:AAK57544.1 xref: EMBL:AAV83778.1 xref: EMBL:AAX14393.1 xref: EMBL:BAD96805.1 xref: EMBL:CAA56869.1 xref: EMBL:CAG29291.1 xref: UniProtKB:Q13765 xref: UniProtKB:Q3KQV4 xref: UniProtKB:Q53A18 xref: UniProtKB:Q53G46 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005154 ! NACA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008025 ! naca-rif1 physical interaction relationship: participates_in CCO:I0019769 ! naca-zhx1 physical interaction relationship: participates_in CCO:I0020080 ! naca-aplp1 physical interaction relationship: transforms_into CCO:B0013085 ! NACA_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0013086 ! NACA_HUMAN-Phosphothreonine92 relationship: transforms_into CCO:B0013087 ! NACA_HUMAN-Phosphothreonine159 relationship: transforms_into CCO:B0013088 ! NACA_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0013089 ! NACA_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0013090 ! NACA_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0068435 ! NACA_HUMAN-Phosphoserine191 [Term] id: CCO:B0006097 name: PNPH_HUMAN def: "Purine nucleoside phosphorylase" [UniProtKB:P00491] synonym: "EC 2.4.2.1" EXACT [UniProtKB:P00491] synonym: "Inosine phosphorylase" EXACT [UniProtKB:P00491] synonym: "PNP" EXACT [UniProtKB:P00491] xref: EMBL:AAA36460.1 xref: EMBL:AAI04207.1 xref: EMBL:AAI04208.1 xref: EMBL:AAI06075.1 xref: EMBL:AAV68044.1 xref: EMBL:CAA25320.1 xref: EMBL:CAG28535.1 xref: UniProtKB:P00491 xref: UniProtKB:Q15160 xref: UniProtKB:Q5PZ03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005350 ! NP_human relationship: has_function CCO:F0001096 ! purine-nucleoside phosphorylase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0003338 ! transferase activity, transferring pentosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008027 ! np-rif1 physical interaction relationship: participates_in CCO:I0008138 ! np-tp53 physical interaction relationship: participates_in CCO:I0019603 ! np-aplp1 physical interaction relationship: participates_in CCO:I0019772 ! np-zhx1 physical interaction relationship: participates_in CCO:I0020093 ! np-dkfzp564o0523 physical interaction relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002713 ! positive regulation of alpha-beta T cell differentiation relationship: transforms_into CCO:B0013592 ! PNPH_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0006098 name: PA1B3_HUMAN def: "Platelet-activating factor acetylhydrolase IB subunit gamma" [UniProtKB:Q15102] synonym: "EC 3.1.1.47" EXACT [UniProtKB:Q15102] synonym: "PAF acetylhydrolase 29 kDa subunit" EXACT [UniProtKB:Q15102] synonym: "PAF-AH 29 kDa subunit" EXACT [UniProtKB:Q15102] synonym: "PAF-AH subunit gamma" EXACT [UniProtKB:Q15102] synonym: "PAFAH subunit gamma" EXACT [UniProtKB:Q15102] xref: EMBL:AAD11989.1 xref: EMBL:AAH03016.1 xref: EMBL:AAH07863.1 xref: EMBL:BAA09706.1 xref: UniProtKB:Q15102 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005251 ! PAFAH1B3_human relationship: has_function CCO:F0000366 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003360 ! hydrolase activity, acting on ester bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008028 ! pafah1b3-rif1 physical interaction relationship: participates_in CCO:I0008029 ! pafah1b3-tp53 physical interaction relationship: participates_in CCO:I0015483 ! pafah1b3-sdcbp2 physical interaction relationship: participates_in CCO:I0019604 ! pafah1b3-med31 physical interaction relationship: participates_in CCO:I0019605 ! pafah1b3-tle1 physical interaction relationship: participates_in CCO:I0019774 ! pafah1b3-g22p1 physical interaction relationship: participates_in CCO:I0019775 ! pafah1b3-setdb1 physical interaction relationship: participates_in CCO:I0019776 ! pafah1b3-zhx1 physical interaction relationship: participates_in CCO:I0020094 ! pafah1b3-gdf9 physical interaction [Term] id: CCO:B0006099 name: PCDA4_HUMAN def: "Protocadherin alpha-4 precursor" [UniProtKB:Q9UN74] synonym: "PCDH-alpha-4" EXACT [UniProtKB:Q9UN74] xref: EMBL:AAC34322.1 xref: EMBL:AAD43706.1 xref: EMBL:AAD43743.1 xref: UniProtKB:O75285 xref: UniProtKB:Q9UN74 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005275 ! PCDHA4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008030 ! pcdha4-tp53 physical interaction relationship: participates_in CCO:I0008140 ! pcdha4-rif1 physical interaction relationship: participates_in CCO:I0019606 ! pcdha4-tle1 physical interaction relationship: participates_in CCO:I0019780 ! pcdha4-aplp1 physical interaction relationship: participates_in CCO:I0019781 ! pcdha4-setdb1 physical interaction relationship: participates_in CCO:I0020096 ! pcdha4-gdf9 physical interaction [Term] id: CCO:B0006100 name: RPB3_HUMAN def: "DNA-directed RNA polymerase II subunit RPB3" [UniProtKB:P19387] synonym: "DNA-directed RNA polymerase II 33 kDa polypeptide" EXACT [UniProtKB:P19387] synonym: "DNA-directed RNA polymerase II subunit C" EXACT [UniProtKB:P19387] synonym: "RNA polymerase II subunit 3" EXACT [UniProtKB:P19387] synonym: "RNA polymerase II subunit B3" EXACT [UniProtKB:P19387] synonym: "RPB31" EXACT [UniProtKB:P19387] synonym: "RPB33" EXACT [UniProtKB:P19387] xref: EMBL:AAA36586.1 xref: EMBL:AAC14355.1 xref: EMBL:AAC24309.1 xref: EMBL:AAH00409.1 xref: EMBL:AAH03159.1 xref: EMBL:AAH28157.1 xref: EMBL:CAA11842.1 xref: EMBL:CAA11843.1 xref: UniProtKB:O15161 xref: UniProtKB:P19387 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005526 ! POLR2C_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0008031 ! polr2c-rif1 physical interaction relationship: participates_in CCO:I0019792 ! polr2c-smarcc2 physical interaction relationship: participates_in CCO:I0019793 ! polr2c-stc2 physical interaction [Term] id: CCO:B0006101 name: RPC6_HUMAN def: "DNA-directed RNA polymerase III subunit RPC6" [UniProtKB:Q9H1D9] synonym: "DNA-directed RNA polymerase III 39 kDa polypeptide" EXACT [UniProtKB:Q9H1D9] synonym: "DNA-directed RNA polymerase III subunit F" EXACT [UniProtKB:Q9H1D9] synonym: "RNA polymerase III subunit C6" EXACT [UniProtKB:Q9H1D9] synonym: "RPC39" EXACT [UniProtKB:Q9H1D9] xref: EMBL:AAB63677.1 xref: EMBL:AAH12588.1 xref: EMBL:CAC11110.1 xref: UniProtKB:O15319 xref: UniProtKB:Q9H1D9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005528 ! POLR3F_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000271 ! DNA-directed RNA polymerase III complex relationship: participates_in CCO:I0008032 ! polr3f-rif1 physical interaction relationship: participates_in CCO:I0018846 ! polr3f-prpf4b-1 physical interaction relationship: participates_in CCO:I0019608 ! polr3f-c14orf1 physical interaction relationship: participates_in CCO:I0019794 ! polr3f-htatip physical interaction relationship: participates_in CCO:I0019795 ! polr3f-stc2 physical interaction relationship: participates_in CCO:I0020405 ! polr3f-c14orf150 physical interaction relationship: participates_in CCO:I0020406 ! polr3f-prpf4b physical interaction relationship: participates_in CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter [Term] id: CCO:B0006102 name: IPYR_HUMAN def: "Inorganic pyrophosphatase" [UniProtKB:Q15181] synonym: "EC 3.6.1.1" EXACT [UniProtKB:Q15181] synonym: "PPase" EXACT [UniProtKB:Q15181] synonym: "Pyrophosphate phospho-hydrolase" EXACT [UniProtKB:Q15181] xref: EMBL:AAD24964.1 xref: EMBL:AAD34643.1 xref: EMBL:AAF17222.1 xref: EMBL:AAG36780.1 xref: EMBL:AAH01022.3 xref: EMBL:AAH61581.2 xref: EMBL:AAI05035.1 xref: EMBL:AAI05037.1 xref: EMBL:AAI07883.1 xref: EMBL:AAP97214.1 xref: EMBL:BAA84702.1 xref: EMBL:CAA88494.1 xref: EMBL:CAI13692.1 xref: UniProtKB:Q15181 xref: UniProtKB:Q2M348 xref: UniProtKB:Q5SQT7 xref: UniProtKB:Q6P7P4 xref: UniProtKB:Q9UQJ5 xref: UniProtKB:Q9Y5B1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004902 ! PPA1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000835 ! inorganic diphosphatase activity relationship: has_function CCO:F0003166 ! pyrophosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008033 ! pp-tp53 physical interaction relationship: participates_in CCO:I0019796 ! pp-setdb1 physical interaction relationship: participates_in CCO:I0020032 ! hspb1-pp physical interaction [Term] id: CCO:B0006103 name: PSD11_HUMAN def: "26S proteasome non-ATPase regulatory subunit 11" [UniProtKB:O00231] synonym: "26S proteasome regulatory subunit p44.5" EXACT [UniProtKB:O00231] synonym: "26S proteasome regulatory subunit S9" EXACT [UniProtKB:O00231] xref: EMBL:AAB58732.1 xref: EMBL:AAH00437.1 xref: EMBL:AAH04430.1 xref: EMBL:BAA19748.1 xref: UniProtKB:O00231 xref: UniProtKB:O00495 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005388 ! PSMD11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008035 ! psmd11-ptn physical interaction relationship: participates_in CCO:I0008036 ! psmd11-rif1 physical interaction relationship: participates_in CCO:I0008037 ! psmd11-tp53 physical interaction relationship: participates_in CCO:I0017148 ! traf6-psmd11 physical interaction relationship: participates_in CCO:I0019609 ! psmd11-med31 physical interaction relationship: participates_in CCO:I0019610 ! psmd11-tle1 physical interaction relationship: participates_in CCO:I0019803 ! psmd11-setdb1 physical interaction relationship: participates_in CCO:I0019804 ! psmd11-zhx1 physical interaction relationship: participates_in CCO:I0020129 ! psmd11-gdf9 physical interaction relationship: transforms_into CCO:B0013623 ! PSD11_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013624 ! PSD11_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0013625 ! PSD11_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0013626 ! PSD11_HUMAN-Phosphoserine272 [Term] id: CCO:B0006104 name: PTPRS_HUMAN def: "Receptor-type tyrosine-protein phosphatase S precursor" [UniProtKB:Q13332] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q13332] synonym: "R-PTP-S" EXACT [UniProtKB:Q13332] synonym: "R-PTP-sigma" EXACT [UniProtKB:Q13332] synonym: "Receptor-type tyrosine-protein phosphatase sigma" EXACT [UniProtKB:Q13332] xref: EMBL:AAB21146.2 xref: EMBL:AAC27825.1 xref: EMBL:AAC50299.1 xref: EMBL:AAC50567.1 xref: EMBL:AAC62832.1 xref: EMBL:AAC62834.1 xref: UniProtKB:O75255 xref: UniProtKB:O75870 xref: UniProtKB:Q13332 xref: UniProtKB:Q15718 xref: UniProtKB:Q16341 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005402 ! PTPRS_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008040 ! ptprs-ptn physical interaction relationship: participates_in CCO:I0019806 ! ptprs-htatip physical interaction relationship: participates_in CCO:I0020132 ! ptprs-chd3 physical interaction relationship: participates_in CCO:I0020133 ! ptprs-pfn2 physical interaction relationship: participates_in CCO:I0020134 ! ptprs-setdb1 physical interaction relationship: participates_in CCO:I0020644 ! rab35-ptprs physical interaction [Term] id: CCO:B0006105 name: RFC5_HUMAN def: "Replication factor C subunit 5" [UniProtKB:P40937] synonym: "A1 36 kDa subunit" EXACT [UniProtKB:P40937] synonym: "Activator 1 36 kDa subunit" EXACT [UniProtKB:P40937] synonym: "Activator 1 subunit 5" EXACT [UniProtKB:P40937] synonym: "Replication factor C 36 kDa subunit" EXACT [UniProtKB:P40937] synonym: "RF-C 36 kDa subunit" EXACT [UniProtKB:P40937] synonym: "RFC36" EXACT [UniProtKB:P40937] xref: EMBL:AAB09784.1 xref: EMBL:AAH01866.1 xref: EMBL:AAH13961.1 xref: EMBL:AAO63493.1 xref: UniProtKB:P40937 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005473 ! RFC5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000281 ! DNA clamp loader activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000268 ! DNA replication factor C complex relationship: participates_in CCO:I0008042 ! rfc5-rif1 physical interaction relationship: participates_in CCO:I0015821 ! rfc4-rfc5 physical interaction relationship: participates_in CCO:I0015869 ! rfc1-rfc2-2 physical interaction relationship: participates_in CCO:I0015870 ! rfc1-rfc2-3 physical interaction relationship: participates_in CCO:I0015871 ! rfc1-rfc2-4 physical interaction relationship: participates_in CCO:I0015872 ! rfc2-rfc3-1 physical interaction relationship: participates_in CCO:I0015873 ! rfc2-rfc4-4 physical interaction relationship: participates_in CCO:I0015874 ! rfc4-rfc3-2 physical interaction relationship: participates_in CCO:I0015878 ! rfc2-rfc4-5 physical interaction relationship: participates_in CCO:I0015879 ! rfc4-rfc5-1 physical interaction relationship: participates_in CCO:I0017805 ! rfc2-rfc3-3 physical interaction relationship: participates_in CCO:I0019330 ! rfc_human physical interaction relationship: participates_in CCO:I0019611 ! rfc5-unc119 physical interaction relationship: participates_in CCO:I0019809 ! rfc5-cops6 physical interaction relationship: participates_in CCO:I0019810 ! rfc5-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019811 ! rfc5-eef1a1 physical interaction relationship: participates_in CCO:I0020148 ! rfc5-med31 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0006106 name: Q6IA98_HUMAN def: "RNPC4 protein" [UniProtKB:Q6IA98] xref: EMBL:CAG33538.1 xref: UniProtKB:Q6IA98 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006006 ! RNPC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008044 ! rnpc4-rpa1 physical interaction relationship: participates_in CCO:I0008316 ! rnpc4-ptn physical interaction relationship: participates_in CCO:I0019540 ! rnpc4-med31 physical interaction relationship: participates_in CCO:I0020150 ! rnpc4-pola2 physical interaction [Term] id: CCO:B0006107 name: SAT1_HUMAN def: "Diamine acetyltransferase 1" [UniProtKB:P21673] synonym: "EC 2.3.1.57" EXACT [UniProtKB:P21673] synonym: "Polyamine N-acetyltransferase 1" EXACT [UniProtKB:P21673] synonym: "Putrescine acetyltransferase" EXACT [UniProtKB:P21673] synonym: "Spermidine/spermine N(1)-acetyltransferase 1" EXACT [UniProtKB:P21673] synonym: "SSAT" EXACT [UniProtKB:P21673] synonym: "SSAT-1" EXACT [UniProtKB:P21673] xref: EMBL:AAA60573.1 xref: EMBL:AAA63260.1 xref: EMBL:AAA98854.1 xref: EMBL:AAH02503.1 xref: EMBL:AAH08424.1 xref: EMBL:AAP35471.1 xref: EMBL:CAA78509.1 xref: UniProtKB:P21673 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005566 ! SAT1_human relationship: has_function CCO:F0000616 ! diamine N-acetyltransferase activity relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008047 ! sat-rif1 physical interaction relationship: participates_in CCO:I0008048 ! sat-tp53 physical interaction relationship: participates_in CCO:I0008161 ! sat-ptn physical interaction relationship: participates_in CCO:I0014999 ! hoxb6-sat physical interaction relationship: participates_in CCO:I0015167 ! fksg26-sat physical interaction relationship: participates_in CCO:I0015241 ! sat-tsc22d4 physical interaction relationship: participates_in CCO:I0015739 ! hoxb9-sat physical interaction relationship: participates_in CCO:I0019548 ! sat-tle1 physical interaction relationship: participates_in CCO:I0019615 ! sat-hspe1 physical interaction relationship: participates_in CCO:I0019616 ! sat-htatip physical interaction relationship: participates_in CCO:I0019821 ! sat-aplp1 physical interaction relationship: participates_in CCO:I0019822 ! sat-med31 physical interaction relationship: participates_in CCO:I0019823 ! sat-ephb6 physical interaction relationship: participates_in CCO:I0019824 ! sat-myst2 physical interaction relationship: participates_in CCO:I0019825 ! sat-setdb1 physical interaction relationship: participates_in CCO:I0019826 ! sat-zhx1 physical interaction relationship: participates_in CCO:I0020162 ! sat-chd3 physical interaction relationship: participates_in CCO:I0020163 ! sat-dgkz physical interaction relationship: participates_in CCO:I0020164 ! sat-gdf9 physical interaction [Term] id: CCO:B0006108 name: SPB9_HUMAN def: "Serpin B9" [UniProtKB:P50453] synonym: "CAP-3" EXACT [UniProtKB:P50453] synonym: "CAP3" EXACT [UniProtKB:P50453] synonym: "Cytoplasmic antiproteinase 3" EXACT [UniProtKB:P50453] synonym: "Proteinase inhibitor 9" EXACT [UniProtKB:P50453] xref: EMBL:AAC41940.1 xref: EMBL:AAC50793.1 xref: EMBL:AAH02538.1 xref: EMBL:AAP35319.1 xref: EMBL:BAB91078.1 xref: EMBL:CAG28555.1 xref: EMBL:CAI23290.1 xref: EMBL:EAW55093.1 xref: UniProtKB:P50453 xref: UniProtKB:Q5TD03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005653 ! SERPINB9_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008050 ! serpinb9-rif1 physical interaction relationship: participates_in CCO:I0008051 ! serpinb9-tp53 physical interaction relationship: participates_in CCO:I0019550 ! serpinb9-crmp1 physical interaction relationship: participates_in CCO:I0019551 ! serpinb9-eef1a1 physical interaction relationship: participates_in CCO:I0019617 ! serpinb9-med31 physical interaction relationship: participates_in CCO:I0019618 ! serpinb9-dkfzp564o05 physical interaction relationship: participates_in CCO:I0019619 ! serpinb9-tle1 physical interaction relationship: participates_in CCO:I0019620 ! serpinb9-ubr1 physical interaction relationship: participates_in CCO:I0019621 ! serpinb9-unc119 physical interaction relationship: participates_in CCO:I0019827 ! serpinb9-c14orf1 physical interaction relationship: participates_in CCO:I0019828 ! serpinb9-cops6 physical interaction relationship: participates_in CCO:I0019829 ! serpinb9-fnbp3 physical interaction relationship: participates_in CCO:I0019830 ! serpinb9-g22p1 physical interaction relationship: participates_in CCO:I0019831 ! serpinb9-igsf21 physical interaction relationship: participates_in CCO:I0019832 ! serpinb9-setdb1 physical interaction relationship: participates_in CCO:I0019833 ! serpinb9-zhx1 physical interaction relationship: participates_in CCO:I0020165 ! serpinb9-ech1 physical interaction relationship: participates_in CCO:I0020166 ! serpinb9-gbp2 physical interaction relationship: participates_in CCO:I0020167 ! serpinb9-gdf9 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006110 name: SMN_HUMAN def: "Survival motor neuron protein" [UniProtKB:Q16637] synonym: "Component of gems 1" EXACT [UniProtKB:Q16637] synonym: "Gemin-1" EXACT [UniProtKB:Q16637] xref: EMBL:AAA64505.1 xref: EMBL:AAA66242.1 xref: EMBL:AAC50473.1 xref: EMBL:AAC52048.1 xref: EMBL:AAC62262.1 xref: EMBL:AAC83178.1 xref: EMBL:AAH00908.1 xref: EMBL:AAH15308.1 xref: EMBL:AAH62723.1 xref: EMBL:AAH70242.1 xref: UniProtKB:Q13119 xref: UniProtKB:Q16637 xref: UniProtKB:Q549U5 xref: UniProtKB:Q96J51 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005633 ! SMN1_human relationship: encoded_by CCO:G0005634 ! SMN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0008053 ! smn1-rif1 physical interaction relationship: participates_in CCO:I0018600 ! gemin5-gemin4-1 physical interaction relationship: participates_in CCO:I0018601 ! gemin5-smn1-1 physical interaction relationship: participates_in CCO:I0020170 ! smn1-gdf9 physical interaction relationship: transforms_into CCO:B0014108 ! SMN_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0014109 ! SMN_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0014110 ! SMN_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0014111 ! SMN_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0014112 ! SMN_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0070647 ! SMN_HUMAN-Phosphothreonine25 [Term] id: CCO:B0006111 name: RSMN_HUMAN def: "Small nuclear ribonucleoprotein-associated protein N" [UniProtKB:P63162] synonym: "Sm protein N" EXACT [UniProtKB:P63162] synonym: "Sm-D" EXACT [UniProtKB:P63162] synonym: "Sm-N" EXACT [UniProtKB:P63162] synonym: "SmN" EXACT [UniProtKB:P63162] synonym: "snRNP-N" EXACT [UniProtKB:P63162] synonym: "Tissue-specific-splicing protein" EXACT [UniProtKB:P63162] xref: EMBL:AAA36617.1 xref: EMBL:AAA98969.1 xref: EMBL:AAH00611.1 xref: EMBL:AAH03180.1 xref: EMBL:AAH24777.1 xref: EMBL:AAH25178.1 xref: EMBL:AAK92481.1 xref: EMBL:CAA33901.1 xref: EMBL:CAG29346.1 xref: UniProtKB:P14648 xref: UniProtKB:P17135 xref: UniProtKB:P63162 xref: UniProtKB:Q0D2Q5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005541 ! SNRPN_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: participates_in CCO:I0008054 ! snrpn-tp53 physical interaction relationship: participates_in CCO:I0008164 ! snrpn-rif1 physical interaction relationship: participates_in CCO:I0019650 ! arf4l-snrpn physical interaction relationship: participates_in CCO:I0019841 ! snrpn-sh3gl3 physical interaction [Term] id: CCO:B0006112 name: ST1E1_HUMAN def: "Estrogen sulfotransferase" [UniProtKB:P49888] synonym: "EC 2.8.2.4" EXACT [UniProtKB:P49888] synonym: "EST-1" EXACT [UniProtKB:P49888] synonym: "Sulfotransferase, estrogen-preferring" EXACT [UniProtKB:P49888] xref: EMBL:AAA82125.1 xref: EMBL:AAB34601.1 xref: EMBL:AAB51658.1 xref: EMBL:AAC50286.1 xref: EMBL:AAH27956.1 xref: EMBL:AAQ97179.1 xref: EMBL:CAA72079.1 xref: UniProtKB:P49888 xref: UniProtKB:Q8N6X5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005677 ! SULT1E1_human relationship: has_function CCO:F0000725 ! estrone sulfotransferase activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001748 ! sulfotransferase activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0007646 ! steroid sulfotransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008055 ! sult1e1-tp53 physical interaction relationship: participates_in CCO:I0008169 ! sult1e1-rif1 physical interaction relationship: participates_in CCO:I0019844 ! sult1e1-setdb1 physical interaction [Term] id: CCO:B0006113 name: SAP18_HUMAN def: "Histone deacetylase complex subunit SAP18" [UniProtKB:O00422] synonym: "2HOR0202" EXACT [UniProtKB:O00422] synonym: "Cell growth-inhibiting protein 38" EXACT [UniProtKB:O00422] synonym: "Sin3-associated polypeptide p18" EXACT [UniProtKB:O00422] synonym: "Sin3-associated polypeptide, 18 kDa" EXACT [UniProtKB:O00422] xref: EMBL:AAC51322.1 xref: EMBL:AAD41090.1 xref: EMBL:AAF21220.1 xref: EMBL:AAH30836.1 xref: EMBL:AAT52216.1 xref: EMBL:CAG33316.1 xref: EMBL:CAH69949.1 xref: UniProtKB:O00422 xref: UniProtKB:Q2TTR4 xref: UniProtKB:Q6IAW9 xref: UniProtKB:Q8N606 xref: UniProtKB:Q9UF14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005562 ! SAP18_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: participates_in CCO:I0008057 ! tada3l-sap18 physical interaction relationship: participates_in CCO:I0016122 ! sap18-hdac1-2 physical interaction relationship: participates_in CCO:I0019498 ! sap18-hdac1-1 physical interaction relationship: participates_in CCO:I0020070 ! mgc3731-sap18 physical interaction relationship: participates_in CCO:I0020155 ! rps3a-sap18 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0006114 name: KITH_HUMAN def: "Thymidine kinase, cytosolic" [UniProtKB:P04183] synonym: "EC 2.7.1.21" EXACT [UniProtKB:P04183] xref: EMBL:AAA61187.1 xref: EMBL:AAA61189.1 xref: EMBL:AAA61191.1 xref: EMBL:AAH06484.1 xref: EMBL:AAH07872.1 xref: EMBL:AAH07986.1 xref: EMBL:AAP35587.1 xref: UniProtKB:P04183 xref: UniProtKB:Q969V0 xref: UniProtKB:Q9UMG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004953 ! TK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001155 ! thymidine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004129 ! nucleoside kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008058 ! tk1-rif1 physical interaction relationship: participates_in CCO:I0008059 ! tk1-tp53 physical interaction relationship: participates_in CCO:I0019632 ! tk1-crmp1 physical interaction relationship: participates_in CCO:I0019633 ! tk1-tle1 physical interaction relationship: participates_in CCO:I0019634 ! tk1-unc119 physical interaction relationship: participates_in CCO:I0019855 ! tk1-aplp1 physical interaction relationship: participates_in CCO:I0019856 ! tk1-c14orf1 physical interaction relationship: participates_in CCO:I0019857 ! tk1-cops6 physical interaction relationship: participates_in CCO:I0019858 ! tk1-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019859 ! tk1-drap1 physical interaction relationship: participates_in CCO:I0019860 ! tk1-setdb1 physical interaction relationship: participates_in CCO:I0020196 ! tk1-gdf9 physical interaction relationship: participates_in CCO:I0020197 ! tk1-ptprk physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0012611 ! KITH_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0012612 ! KITH_HUMAN-Phosphoserine231 [Term] id: CCO:B0006115 name: TYB4_HUMAN def: "Thymosin beta-4" [UniProtKB:P62328] synonym: "Fx" EXACT [UniProtKB:P62328] synonym: "T beta-4" EXACT [UniProtKB:P62328] xref: EMBL:AAA36745.1 xref: EMBL:AAP35753.1 xref: EMBL:CAA26323.1 xref: EMBL:CAC43317.1 xref: UniProtKB:P01253 xref: UniProtKB:P01254 xref: UniProtKB:P62328 xref: UniProtKB:Q546P5 xref: UniProtKB:Q63576 xref: UniProtKB:Q9UE55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005850 ! TMSB4X_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008060 ! tmsb4x-tp53 physical interaction relationship: participates_in CCO:I0008175 ! tmsb4x-rif1 physical interaction relationship: participates_in CCO:I0019635 ! tmsb4x-unc119 physical interaction relationship: participates_in CCO:I0019863 ! tmsb4x-eef1a1 physical interaction relationship: participates_in CCO:I0019864 ! tmsb4x-tle1 physical interaction relationship: participates_in CCO:I0020198 ! tmsb4x-aplp1 physical interaction relationship: participates_in CCO:I0020199 ! tmsb4x-igsf21 physical interaction relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0014557 ! TYB4_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0014558 ! TYB4_HUMAN-Phosphothreonine23 [Term] id: CCO:B0006116 name: TOM20_HUMAN def: "Mitochondrial import receptor subunit TOM20 homolog" [UniProtKB:Q15388] synonym: "Mitochondrial 20 kDa outer membrane protein" EXACT [UniProtKB:Q15388] synonym: "Outer mitochondrial membrane receptor Tom20" EXACT [UniProtKB:Q15388] xref: EMBL:AAF13354.1 xref: EMBL:AAH00882.1 xref: EMBL:AAH66335.1 xref: EMBL:AAH71994.1 xref: EMBL:AAI00287.1 xref: EMBL:AAI07852.1 xref: EMBL:BAA02804.1 xref: EMBL:BAF82499.1 xref: EMBL:CAG32999.1 xref: EMBL:CAI21937.1 xref: EMBL:EAW70003.1 xref: UniProtKB:A8K195 xref: UniProtKB:Q15388 xref: UniProtKB:Q498B3 xref: UniProtKB:Q6IBT4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005809 ! TOMM20_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000328 ! mitochondrial outer membrane translocase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: participates_in CCO:I0008061 ! tomm20-ptn physical interaction relationship: participates_in CCO:I0020487 ! tomm20-apoa1 physical interaction relationship: transforms_into CCO:B0014425 ! TOM20_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0014426 ! TOM20_HUMAN-Phosphoserine138 [Term] id: CCO:B0006117 name: AK1C3_HUMAN def: "Aldo-keto reductase family 1 member C3" [UniProtKB:P42330] synonym: "17-beta-HSD 5" EXACT [UniProtKB:P42330] synonym: "17-beta-hydroxysteroid dehydrogenase type 5" EXACT [UniProtKB:P42330] synonym: "3-alpha-HSD type 2" EXACT [UniProtKB:P42330] synonym: "3-alpha-HSD type II, brain" EXACT [UniProtKB:P42330] synonym: "3-alpha-hydroxysteroid dehydrogenase type 2" EXACT [UniProtKB:P42330] synonym: "Chlordecone reductase homolog HAKRb" EXACT [UniProtKB:P42330] synonym: "DD-3" EXACT [UniProtKB:P42330] synonym: "DD3" EXACT [UniProtKB:P42330] synonym: "Dihydrodiol dehydrogenase 3" EXACT [UniProtKB:P42330] synonym: "Dihydrodiol dehydrogenase type I" EXACT [UniProtKB:P42330] synonym: "EC 1.-.-.-" EXACT [UniProtKB:P42330] synonym: "EC 1.1.1.188" EXACT [UniProtKB:P42330] synonym: "EC 1.1.1.213" EXACT [UniProtKB:P42330] synonym: "EC 1.1.1.63" EXACT [UniProtKB:P42330] synonym: "EC 1.1.1.64" EXACT [UniProtKB:P42330] synonym: "EC 1.3.1.20" EXACT [UniProtKB:P42330] synonym: "HA1753" EXACT [UniProtKB:P42330] synonym: "PGFS" EXACT [UniProtKB:P42330] synonym: "Prostaglandin F synthase" EXACT [UniProtKB:P42330] synonym: "Testosterone 17-beta-dehydrogenase 5" EXACT [UniProtKB:P42330] synonym: "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase" EXACT [UniProtKB:P42330] xref: EMBL:AAB41916.1 xref: EMBL:AAD14011.1 xref: EMBL:AAF07272.2 xref: EMBL:AAH01479.1 xref: EMBL:AAH19230.1 xref: EMBL:AAP35950.1 xref: EMBL:BAA04619.2 xref: EMBL:BAA88488.1 xref: EMBL:BAA88489.1 xref: EMBL:BAA92892.1 xref: EMBL:CAI14729.1 xref: UniProtKB:P42330 xref: UniProtKB:Q5T2L1 xref: UniProtKB:Q96DJ1 xref: UniProtKB:Q96KI8 xref: UniProtKB:Q99530 xref: UniProtKB:Q9UCX1 xref: UniProtKB:Q9UII3 xref: UniProtKB:Q9UKL9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004041 ! AKR1C3_human relationship: has_function CCO:F0000511 ! aldo-keto reductase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006330 ! prostaglandin-F synthase activity relationship: has_function CCO:F0006339 ! 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity relationship: has_function CCO:F0006358 ! testosterone 17-beta-dehydrogenase (NADP+) activity relationship: has_function CCO:F0006427 ! trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity relationship: has_function CCO:F0007679 ! testosterone 17-beta-dehydrogenase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008063 ! akr1c3-rif1 physical interaction relationship: participates_in CCO:I0019890 ! akr1c3-zhx1 physical interaction relationship: participates_in CCO:I0020506 ! akr1c3-acin1 physical interaction [Term] id: CCO:B0006119 name: ANXA3_HUMAN def: "Annexin A3" [UniProtKB:P12429] synonym: "35-alpha calcimedin" EXACT [UniProtKB:P12429] synonym: "Annexin III" EXACT [UniProtKB:P12429] synonym: "Annexin-3" EXACT [UniProtKB:P12429] synonym: "Inositol 1,2-cyclic phosphate 2-phosphohydrolase" EXACT [UniProtKB:P12429] synonym: "Lipocortin III" EXACT [UniProtKB:P12429] synonym: "PAP-III" EXACT [UniProtKB:P12429] synonym: "Placental anticoagulant protein III" EXACT [UniProtKB:P12429] xref: EMBL:AAA16713.1 xref: EMBL:AAA52284.1 xref: EMBL:AAA59496.1 xref: EMBL:AAH00871.1 xref: EMBL:CAG28576.1 xref: UniProtKB:P12429 xref: UniProtKB:Q6LET2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004070 ! ANXA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008065 ! anxa3-tp53 physical interaction relationship: participates_in CCO:I0019646 ! anxa3-ubr1 physical interaction relationship: participates_in CCO:I0019647 ! anxa3-unc119 physical interaction relationship: participates_in CCO:I0019892 ! anxa3-igsf21 physical interaction relationship: participates_in CCO:I0020520 ! c2f-anxa3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0041284 ! ANXA3_HUMAN-N-acetylalanine2 [Term] id: CCO:B0006120 name: ARL3_HUMAN def: "ADP-ribosylation factor-like protein 3" [UniProtKB:P36405] xref: EMBL:AAA21654.1 xref: EMBL:AAH09841.1 xref: EMBL:AAM12603.1 xref: EMBL:CAI40862.1 xref: UniProtKB:P36405 xref: UniProtKB:Q5JSM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004095 ! ARL3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0008067 ! arl3-rif1 physical interaction relationship: participates_in CCO:I0008068 ! arl3-tp53 physical interaction relationship: participates_in CCO:I0019653 ! arl3-pde6d physical interaction relationship: participates_in CCO:I0019654 ! arl3-tle1 physical interaction relationship: participates_in CCO:I0019655 ! arl3-ubr1 physical interaction relationship: participates_in CCO:I0019656 ! arl3-unc119 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0006121 name: ATF3_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-3" [UniProtKB:P18847] synonym: "Activating transcription factor 3" EXACT [UniProtKB:P18847] xref: EMBL:AAA20506.1 xref: EMBL:AAH06322.1 xref: EMBL:AAQ93358.1 xref: UniProtKB:P18847 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004114 ! ATF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007150 ! cbp-atf3 physical interaction relationship: participates_in CCO:I0008069 ! atf3-tp53 physical interaction relationship: participates_in CCO:I0008192 ! atf3-rif1 physical interaction relationship: participates_in CCO:I0018555 ! rela-atf3 direct interaction relationship: participates_in CCO:I0018556 ! rela-atf3-1 direct interaction relationship: participates_in CCO:I0018558 ! rela-cbp-1 physical interaction relationship: participates_in CCO:I0019914 ! atf3-igsf21 physical interaction relationship: participates_in CCO:I0019994 ! fgfr3-atf3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0006122 name: ATPG_HUMAN def: "ATP synthase subunit gamma, mitochondrial precursor" [UniProtKB:P36542] synonym: "F-ATPase gamma subunit" EXACT [UniProtKB:P36542] xref: EMBL:AAH00470.1 xref: EMBL:AAH00931.1 xref: EMBL:AAH13394.1 xref: EMBL:AAH16812.1 xref: EMBL:AAH20824.1 xref: EMBL:BAA03994.1 xref: EMBL:BAA03995.1 xref: EMBL:BAA03996.1 xref: EMBL:BAA03997.1 xref: EMBL:CAH73454.1 xref: EMBL:CAI12961.1 xref: UniProtKB:P36542 xref: UniProtKB:Q5VYP3 xref: UniProtKB:Q96AS8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004121 ! ATP5C1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008070 ! atp5c1-ptn physical interaction relationship: participates_in CCO:I0008194 ! atp5c1-ccnd3 physical interaction relationship: participates_in CCO:I0008360 ! atp5c1-egfr physical interaction relationship: participates_in CCO:I0019565 ! atp5c1-mpp1 physical interaction relationship: participates_in CCO:I0019664 ! atp5c1-pola2 physical interaction relationship: participates_in CCO:I0019915 ! atp5c1-u222 physical interaction relationship: participates_in CCO:I0019916 ! atp5c1-pcqap physical interaction relationship: participates_in CCO:I0020515 ! atp5c1-pawr physical interaction relationship: participates_in CCO:I0020516 ! atp5c1-znf337 physical interaction relationship: transforms_into CCO:B0010691 ! ATPG_HUMAN-N6-acetyllysine79 relationship: transforms_into CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: transforms_into CCO:B0010693 ! ATPG_HUMAN-N6-acetyllysine115 [Term] id: CCO:B0006123 name: BCR_HUMAN def: "Breakpoint cluster region protein" [UniProtKB:P11274] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P11274] synonym: "Renal carcinoma antigen NY-REN-26" EXACT [UniProtKB:P11274] xref: EMBL:AAA35594.1 xref: EMBL:AAB60388.1 xref: EMBL:BAE06073.1 xref: EMBL:CAA26441.1 xref: EMBL:CAA32806.1 xref: EMBL:CAA37010.1 xref: EMBL:CAA37011.1 xref: EMBL:CAA68676.1 xref: UniProtKB:P11274 xref: UniProtKB:P78501 xref: UniProtKB:Q12842 xref: UniProtKB:Q4LE80 xref: UniProtKB:Q6NZI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004156 ! BCR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0008072 ! bcr-tp53 physical interaction relationship: participates_in CCO:I0019667 ! bcr-unc119 physical interaction relationship: participates_in CCO:I0019926 ! bcr-igsf21 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0010778 ! BCR_HUMAN-Phosphotyrosine177 relationship: transforms_into CCO:B0010779 ! BCR_HUMAN-Phosphothreonine310 relationship: transforms_into CCO:B0010780 ! BCR_HUMAN-Phosphoserine459 relationship: transforms_into CCO:B0010781 ! BCR_HUMAN-Phosphoserine463 relationship: transforms_into CCO:B0010782 ! BCR_HUMAN-Phosphotyrosine591 relationship: transforms_into CCO:B0010783 ! BCR_HUMAN-Phosphotyrosine644 relationship: transforms_into CCO:B0010784 ! BCR_HUMAN-Phosphoserine1264 relationship: transforms_into CCO:B0031297 ! BCR_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0031298 ! BCR_HUMAN-Phosphotyrosine246 relationship: transforms_into CCO:B0048177 ! BCR_HUMAN-Phosphoserine122 [Term] id: CCO:B0006124 name: Q5T8Z1_HUMAN def: "BMI1 polycomb ring finger oncogene" [UniProtKB:Q5T8Z1] xref: EMBL:CAI15957.1 xref: UniProtKB:Q5T8Z1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005999 ! BMI1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008073 ! bmi1-rif1 physical interaction relationship: participates_in CCO:I0008201 ! bmi1-ptn physical interaction relationship: participates_in CCO:I0019670 ! bmi1-htatip physical interaction [Term] id: CCO:B0006125 name: CAPZB_HUMAN def: "F-actin-capping protein subunit beta" [UniProtKB:P47756] synonym: "CapZ beta" EXACT [UniProtKB:P47756] xref: EMBL:AAA87395.1 xref: EMBL:AAH24601.1 xref: EMBL:AAV38277.1 xref: EMBL:AAV38278.1 xref: EMBL:CAH71392.1 xref: EMBL:CAH72124.1 xref: EMBL:CAI22231.1 xref: UniProtKB:P47756 xref: UniProtKB:Q5U0L4 xref: UniProtKB:Q8TB49 xref: UniProtKB:Q9NUC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004219 ! CAPZB_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000542 ! F-actin capping protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008074 ! capzb-ptn physical interaction relationship: participates_in CCO:I0016712 ! map3k3-capzb physical interaction relationship: participates_in CCO:I0020266 ! capzb-mrpl20 physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0010913 ! CAPZB_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0010914 ! CAPZB_HUMAN-Phosphoserine182 [Term] id: CCO:B0006126 name: CBX1_HUMAN def: "Chromobox protein homolog 1" [UniProtKB:P83916] synonym: "Heterochromatin protein 1 homolog beta" EXACT [UniProtKB:P83916] synonym: "Heterochromatin protein p25" EXACT [UniProtKB:P83916] synonym: "HP1 beta" EXACT [UniProtKB:P83916] synonym: "HP1Hsbeta" EXACT [UniProtKB:P83916] synonym: "M31" EXACT [UniProtKB:P83916] synonym: "Modifier 1 protein" EXACT [UniProtKB:P83916] synonym: "p25beta" EXACT [UniProtKB:P83916] xref: EMBL:AAB81548.1 xref: EMBL:AAH02609.1 xref: EMBL:AAH21302.1 xref: UniProtKB:P23197 xref: UniProtKB:P83916 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004231 ! CBX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008075 ! cbx1-rif1 physical interaction relationship: transforms_into CCO:B0010965 ! CBX1_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0010966 ! CBX1_HUMAN-Phosphoserine175 [Term] id: CCO:B0006127 name: BAT3_HUMAN def: "Large proline-rich protein BAT3" [UniProtKB:P46379] synonym: "HLA-B-associated transcript 3" EXACT [UniProtKB:P46379] synonym: "Protein G3" EXACT [UniProtKB:P46379] xref: EMBL:AAA35587.1 xref: EMBL:AAA35588.1 xref: EMBL:AAD18085.1 xref: EMBL:AAH03133.1 xref: EMBL:BAB63390.1 xref: EMBL:CAI17658.1 xref: EMBL:CAI17659.1 xref: EMBL:CAI17784.1 xref: EMBL:CAI17785.1 xref: EMBL:CAI17786.1 xref: EMBL:CAI18314.1 xref: EMBL:CAI18315.1 xref: EMBL:CAI18316.2 xref: EMBL:CAI18318.2 xref: EMBL:CAI18501.1 xref: EMBL:CAI18504.1 xref: EMBL:CAI18508.2 xref: EMBL:CAI18509.1 xref: EMBL:CAI46045.1 xref: EMBL:CAM25014.1 xref: EMBL:CAM45799.1 xref: EMBL:CAM45800.1 xref: EMBL:CAM45801.1 xref: EMBL:CAO72072.1 xref: UniProtKB:A2ADJ7 xref: UniProtKB:A3KQ42 xref: UniProtKB:A3KQ44 xref: UniProtKB:A6NGY6 xref: UniProtKB:A6PWF7 xref: UniProtKB:O95874 xref: UniProtKB:P46379 xref: UniProtKB:Q5HYL9 xref: UniProtKB:Q5SQ35 xref: UniProtKB:Q5SQ36 xref: UniProtKB:Q5SQ37 xref: UniProtKB:Q5SQ41 xref: UniProtKB:Q5SRP8 xref: UniProtKB:Q5SRP9 xref: UniProtKB:Q5STC1 xref: UniProtKB:Q5STX1 xref: UniProtKB:Q5STX3 xref: UniProtKB:Q96SA6 xref: UniProtKB:Q9BCN4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004140 ! BAT3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008079 ! cdk4-bat3 physical interaction relationship: participates_in CCO:I0008984 ! edn1-bat3 physical interaction relationship: participates_in CCO:I0019119 ! atxn2-bat3 physical interaction relationship: participates_in CCO:I0019563 ! arpc3-bat3 physical interaction relationship: participates_in CCO:I0019566 ! bat3-ikbkap physical interaction relationship: participates_in CCO:I0019567 ! bat3-setdb1 physical interaction relationship: participates_in CCO:I0019947 ! chn2-bat3 physical interaction relationship: participates_in CCO:I0019964 ! ctsb-bat3 physical interaction relationship: participates_in CCO:I0020130 ! pth-bat3 physical interaction relationship: participates_in CCO:I0020146 ! reg1b-bat3 physical interaction relationship: participates_in CCO:I0020159 ! s100a4-bat3 physical interaction relationship: participates_in CCO:I0020180 ! tac1-bat3 physical interaction relationship: participates_in CCO:I0020259 ! c19orf10-bat3 physical interaction relationship: participates_in CCO:I0020340 ! igfbp5-bat3 physical interaction relationship: participates_in CCO:I0020413 ! prnp-bat3 physical interaction relationship: participates_in CCO:I0020429 ! rab8a-bat3 physical interaction relationship: participates_in CCO:I0020476 ! tdgf1-bat3 physical interaction relationship: participates_in CCO:I0020561 ! glra2-bat3 physical interaction relationship: transforms_into CCO:B0010747 ! BAT3_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0010748 ! BAT3_HUMAN-Phosphoserine964 relationship: transforms_into CCO:B0010749 ! BAT3_HUMAN-Phosphoserine973 relationship: transforms_into CCO:B0010750 ! BAT3_HUMAN-Phosphoserine1039 relationship: transforms_into CCO:B0010751 ! BAT3_HUMAN-Phosphotyrosine1042 relationship: transforms_into CCO:B0010752 ! BAT3_HUMAN-Phosphoserine1117 [Term] id: CCO:B0006130 name: PDE6D_HUMAN def: "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta" [UniProtKB:O43924] synonym: "EC 3.1.4.17" EXACT [UniProtKB:O43924] synonym: "GMP-PDE delta" EXACT [UniProtKB:O43924] synonym: "p17 protein" EXACT [UniProtKB:O43924] xref: EMBL:AAB87872.1 xref: EMBL:AAC25953.1 xref: EMBL:AAC39720.1 xref: EMBL:AAH07831.1 xref: EMBL:AAP35942.1 xref: EMBL:CAA04880.1 xref: UniProtKB:O43250 xref: UniProtKB:O43924 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005286 ! PDE6D_human relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008085 ! cetn3-pde6d physical interaction relationship: participates_in CCO:I0015843 ! arl2-pde6d physical interaction relationship: participates_in CCO:I0019653 ! arl3-pde6d physical interaction relationship: participates_in CCO:I0019689 ! cdc42-pde6d physical interaction relationship: participates_in CCO:I0020418 ! rab18-pde6d physical interaction [Term] id: CCO:B0006131 name: KCRS_HUMAN def: "Creatine kinase, sarcomeric mitochondrial precursor" [UniProtKB:P17540] synonym: "Basic-type mitochondrial creatine kinase" EXACT [UniProtKB:P17540] synonym: "EC 2.7.3.2" EXACT [UniProtKB:P17540] synonym: "Mib-CK" EXACT [UniProtKB:P17540] synonym: "S-MtCK" EXACT [UniProtKB:P17540] xref: EMBL:AAA60561.1 xref: EMBL:AAH29140.1 xref: EMBL:CAG29311.1 xref: UniProtKB:P17540 xref: UniProtKB:Q6ICS8 xref: UniProtKB:Q8N1E1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004935 ! CKMT2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000583 ! creatine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008088 ! ckmt2-rif1 physical interaction [Term] id: CCO:B0006132 name: CREL1_HUMAN def: "Cysteine-rich with EGF-like domain protein 1 precursor" [UniProtKB:Q96HD1] xref: EMBL:AAH08720.1 xref: EMBL:AAM75206.1 xref: EMBL:AAQ88729.1 xref: EMBL:BAG36806.1 xref: EMBL:CAB43376.1 xref: EMBL:CAG33661.1 xref: UniProtKB:A8MX90 xref: UniProtKB:B2RAA9 xref: UniProtKB:Q6I9X5 xref: UniProtKB:Q8NFT4 xref: UniProtKB:Q96HD1 xref: UniProtKB:Q9Y409 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004397 ! CRELD1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008090 ! creld1-ptn physical interaction relationship: participates_in CCO:I0019698 ! creld1-gdf9 physical interaction relationship: participates_in CCO:I0019699 ! creld1-setdb1 physical interaction relationship: participates_in CCO:I0019960 ! creld1-htatip physical interaction relationship: participates_in CCO:I0019961 ! creld1-pola2 physical interaction relationship: participates_in CCO:I0020042 ! itgb3bp-creld1 physical interaction [Term] id: CCO:B0006133 name: CSN6_HUMAN def: "COP9 signalosome complex subunit 6" [UniProtKB:Q7L5N1] synonym: "hVIP" EXACT [UniProtKB:Q7L5N1] synonym: "JAB1-containing signalosome subunit 6" EXACT [UniProtKB:Q7L5N1] synonym: "MOV34 homolog" EXACT [UniProtKB:Q7L5N1] synonym: "SGN6" EXACT [UniProtKB:Q7L5N1] synonym: "Signalosome subunit 6" EXACT [UniProtKB:Q7L5N1] synonym: "Vpr-interacting protein" EXACT [UniProtKB:Q7L5N1] xref: EMBL:AAD03469.1 xref: EMBL:AAH02520.2 xref: UniProtKB:O15387 xref: UniProtKB:Q7L5N1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004409 ! COPS6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000530 ! signalosome relationship: participates_in CCO:I0008093 ! dleu1-cops6 physical interaction relationship: participates_in CCO:I0008149 ! pmf1-cops6 physical interaction relationship: participates_in CCO:I0008214 ! cdkn2c-cops6 physical interaction relationship: participates_in CCO:I0008227 ! ep300-cops6 physical interaction relationship: participates_in CCO:I0008236 ! smpd3-cops6 physical interaction relationship: participates_in CCO:I0008268 ! mnat1-cops6 physical interaction relationship: participates_in CCO:I0008303 ! pten-cops6 physical interaction relationship: participates_in CCO:I0008983 ! edn1-cops6 physical interaction relationship: participates_in CCO:I0019674 ! trib3-cops6 physical interaction relationship: participates_in CCO:I0019754 ! lama4-cops6 physical interaction relationship: participates_in CCO:I0019799 ! prkra-cops6 physical interaction relationship: participates_in CCO:I0019809 ! rfc5-cops6 physical interaction relationship: participates_in CCO:I0019814 ! rpa2-cops6 physical interaction relationship: participates_in CCO:I0019828 ! serpinb9-cops6 physical interaction relationship: participates_in CCO:I0019857 ! tk1-cops6 physical interaction relationship: participates_in CCO:I0019883 ! znf24-cops6 physical interaction relationship: participates_in CCO:I0019975 ! dnmt2-cops6 physical interaction relationship: participates_in CCO:I0020077 ! mycbp-cops6 physical interaction relationship: participates_in CCO:I0020104 ! pfkl-cops6 physical interaction relationship: participates_in CCO:I0020139 ! rab27a-cops6 physical interaction relationship: participates_in CCO:I0020187 ! tdgf1-cops6 physical interaction relationship: participates_in CCO:I0020217 ! zfhx1b-cops6 physical interaction relationship: participates_in CCO:I0020446 ! s100a10-cops6 physical interaction relationship: participates_in CCO:I0020452 ! serpina5-cops6 physical interaction relationship: participates_in CCO:I0020531 ! chrnb1-cops6 physical interaction [Term] id: CCO:B0006134 name: UT14A_HUMAN def: "U3 small nucleolar RNA-associated protein 14 homolog A" [UniProtKB:Q9BVJ6] synonym: "Antigen NY-CO-16" EXACT [UniProtKB:Q9BVJ6] synonym: "Serologically defined colon cancer antigen 16" EXACT [UniProtKB:Q9BVJ6] xref: EMBL:AAH01149.1 xref: EMBL:AAH09649.1 xref: EMBL:AAH14987.1 xref: EMBL:CAI42908.1 xref: EMBL:CAI42909.1 xref: UniProtKB:Q5JYF1 xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005889 ! UTP14A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008096 ! dleu1-utp14a physical interaction relationship: participates_in CCO:I0008181 ! tp53bp2-utp14a physical interaction relationship: participates_in CCO:I0008199 ! axin1-utp14a physical interaction relationship: participates_in CCO:I0008337 ! terf1-utp14a physical interaction relationship: participates_in CCO:I0008422 ! pten-utp14a physical interaction relationship: participates_in CCO:I0015522 ! ldoc1-utp14a physical interaction relationship: participates_in CCO:I0016052 ! gadd45g-utp14a-1 physical interaction relationship: participates_in CCO:I0016072 ! hd-utp14a physical interaction relationship: participates_in CCO:I0018168 ! gadd45g-utp14a physical interaction relationship: participates_in CCO:I0019545 ! rpa2-utp14a physical interaction relationship: participates_in CCO:I0019578 ! cpe-utp14a physical interaction relationship: participates_in CCO:I0019784 ! pdcd5-utp14a physical interaction relationship: participates_in CCO:I0019808 ! rabif-utp14a physical interaction relationship: participates_in CCO:I0019885 ! znf24-utp14a physical interaction relationship: participates_in CCO:I0019894 ! aplp1-utp14a physical interaction relationship: participates_in CCO:I0019977 ! dnmt2-utp14a physical interaction relationship: participates_in CCO:I0020021 ! hbxip-utp14a physical interaction relationship: participates_in CCO:I0020107 ! phf10-utp14a physical interaction relationship: participates_in CCO:I0020175 ! ssr1-utp14a physical interaction relationship: participates_in CCO:I0020436 ! rgs1-utp14a physical interaction relationship: transforms_into CCO:B0014585 ! UT14A_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0014586 ! UT14A_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0014587 ! UT14A_HUMAN-Phosphoserine434 relationship: transforms_into CCO:B0014588 ! UT14A_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0014589 ! UT14A_HUMAN-Phosphoserine445 relationship: transforms_into CCO:B0014590 ! UT14A_HUMAN-Phosphoserine451 relationship: transforms_into CCO:B0014591 ! UT14A_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0071761 ! UT14A_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0071762 ! UT14A_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0071763 ! UT14A_HUMAN-Phosphoserine405 relationship: transforms_into CCO:B0071764 ! UT14A_HUMAN-Phosphoserine407 [Term] id: CCO:B0006135 name: UBR1_HUMAN def: "E3 ubiquitin-protein ligase UBR1" [UniProtKB:Q8IWV7] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8IWV7] synonym: "N-recognin-1" EXACT [UniProtKB:Q8IWV7] synonym: "Ubiquitin-protein ligase E3-alpha-1" EXACT [UniProtKB:Q8IWV7] synonym: "Ubiquitin-protein ligase E3-alpha-I" EXACT [UniProtKB:Q8IWV7] xref: EMBL:AAC23677.1 xref: EMBL:AAC39845.1 xref: EMBL:AAI13506.1 xref: EMBL:AAI13508.1 xref: EMBL:AAL32103.1 xref: EMBL:AAO14997.1 xref: EMBL:BAB55380.1 xref: EMBL:CAH18181.1 xref: UniProtKB:O60708 xref: UniProtKB:O75492 xref: UniProtKB:Q14D45 xref: UniProtKB:Q68DN9 xref: UniProtKB:Q8IWV7 xref: UniProtKB:Q8IWY6 xref: UniProtKB:Q96JY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005874 ! UBR1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008098 ! dleu1-ubr1 physical interaction relationship: participates_in CCO:I0019561 ! arf4l-ubr1 physical interaction relationship: participates_in CCO:I0019620 ! serpinb9-ubr1 physical interaction relationship: participates_in CCO:I0019646 ! anxa3-ubr1 physical interaction relationship: participates_in CCO:I0019655 ! arl3-ubr1 physical interaction relationship: participates_in CCO:I0019690 ! cdc42-ubr1 physical interaction relationship: participates_in CCO:I0019721 ! fth1-ubr1 physical interaction relationship: participates_in CCO:I0019755 ! lama4-ubr1 physical interaction relationship: participates_in CCO:I0019867 ! tp53i3-ubr1 physical interaction relationship: participates_in CCO:I0020183 ! tac3-ubr1 physical interaction relationship: transforms_into CCO:B0014572 ! UBR1_HUMAN-Phosphothreonine21 relationship: transforms_into CCO:B0014573 ! UBR1_HUMAN-Phosphoserine1179 [Term] id: CCO:B0006136 name: DJB11_HUMAN def: "DnaJ homolog subfamily B member 11 precursor" [UniProtKB:Q9UBS4] synonym: "ABBP-2" EXACT [UniProtKB:Q9UBS4] synonym: "APOBEC1-binding protein 2" EXACT [UniProtKB:Q9UBS4] synonym: "ER-associated DNAJ" EXACT [UniProtKB:Q9UBS4] synonym: "ER-associated dnaJ protein 3" EXACT [UniProtKB:Q9UBS4] synonym: "ER-associated Hsp40 co-chaperone" EXACT [UniProtKB:Q9UBS4] synonym: "ERdj3" EXACT [UniProtKB:Q9UBS4] synonym: "ERj3p" EXACT [UniProtKB:Q9UBS4] synonym: "hDj9" EXACT [UniProtKB:Q9UBS4] synonym: "HEDJ" EXACT [UniProtKB:Q9UBS4] synonym: "PWP1-interacting protein 4" EXACT [UniProtKB:Q9UBS4] xref: EMBL:AAF61711.1 xref: EMBL:AAH01144.1 xref: EMBL:AAK69110.1 xref: EMBL:AAP35712.1 xref: EMBL:AAQ89402.1 xref: EMBL:BAA88307.1 xref: EMBL:BAC11533.1 xref: EMBL:BAC11617.1 xref: EMBL:CAB65118.1 xref: EMBL:CAG33377.1 xref: EMBL:EAW78190.1 xref: UniProtKB:Q542Y5 xref: UniProtKB:Q542Y9 xref: UniProtKB:Q6IAQ8 xref: UniProtKB:Q96JC6 xref: UniProtKB:Q9UBS4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004475 ! DNAJB11_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: participates_in CCO:I0008099 ! dnajb11-ptn physical interaction [Term] id: CCO:B0006137 name: DNJB9_HUMAN def: "DnaJ homolog subfamily B member 9" [UniProtKB:Q9UBS3] synonym: "Mdg-1" EXACT [UniProtKB:Q9UBS3] synonym: "Microvascular endothelial differentiation gene 1 protein" EXACT [UniProtKB:Q9UBS3] xref: EMBL:AAD39845.1 xref: EMBL:AAH28912.1 xref: EMBL:AAQ89404.1 xref: EMBL:BAA84703.1 xref: EMBL:CAB45701.1 xref: UniProtKB:Q9UBS3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004491 ! DNAJB9_human relationship: has_function CCO:F0004341 ! chaperone regulator activity relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:I0008100 ! dnajb9-plk1 physical interaction relationship: participates_in CCO:I0019971 ! dnajb9-dncl1 physical interaction relationship: participates_in CCO:I0019972 ! dnajb9-fscn1 physical interaction relationship: participates_in CCO:I0019973 ! dnajb9-tcea2 physical interaction [Term] id: CCO:B0006138 name: TRDMT_HUMAN def: "tRNA (cytosine-5-)-methyltransferase" [UniProtKB:O14717] synonym: "DNA (cytosine-5)-methyltransferase-like protein 2" EXACT [UniProtKB:O14717] synonym: "DNA methyltransferase homolog HsaIIP" EXACT [UniProtKB:O14717] synonym: "DNA MTase homolog HsaIIP" EXACT [UniProtKB:O14717] synonym: "Dnmt2" EXACT [UniProtKB:O14717] synonym: "EC 2.1.1.29" EXACT [UniProtKB:O14717] synonym: "M.HsaIIP" EXACT [UniProtKB:O14717] synonym: "PuMet" EXACT [UniProtKB:O14717] xref: EMBL:AAC39764.1 xref: EMBL:AAC51939.1 xref: EMBL:AAK68033.1 xref: EMBL:AAK68034.1 xref: EMBL:AAK68035.1 xref: EMBL:AAK68036.1 xref: EMBL:AAK68037.1 xref: EMBL:CAA11272.1 xref: EMBL:CAB87964.1 xref: UniProtKB:O14717 xref: UniProtKB:O43669 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005826 ! TRDMT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000405 ! DNA (cytosine-5-)-methyltransferase activity relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003150 ! tRNA (cytosine-5-)-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008101 ! dnmt2-rif1 physical interaction relationship: participates_in CCO:I0019584 ! dnmt2-unc119 physical interaction relationship: participates_in CCO:I0019708 ! dnmt2-eef1a1 physical interaction relationship: participates_in CCO:I0019709 ! dnmt2-setdb1 physical interaction relationship: participates_in CCO:I0019975 ! dnmt2-cops6 physical interaction relationship: participates_in CCO:I0019976 ! dnmt2-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019977 ! dnmt2-utp14a physical interaction relationship: participates_in CCO:I0019978 ! dnmt2-stx1a physical interaction relationship: participates_in CCO:I0020285 ! ddx24-dnmt2 physical interaction relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0006140 name: FXR1_HUMAN def: "Fragile X mental retardation syndrome-related protein 1" [UniProtKB:P51114] synonym: "hFXR1p" EXACT [UniProtKB:P51114] xref: EMBL:AAC50155.1 xref: EMBL:AAH28983.1 xref: EMBL:AAQ20045.1 xref: EMBL:BAF85322.1 xref: UniProtKB:A8K9B8 xref: UniProtKB:P51114 xref: UniProtKB:Q7Z450 xref: UniProtKB:Q8N6R8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004664 ! FXR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008107 ! fxr1-rif1 physical interaction relationship: transforms_into CCO:B0011903 ! FXR1_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0011904 ! FXR1_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0011905 ! FXR1_HUMAN-Omega-N-methylated arginine445 relationship: transforms_into CCO:B0011906 ! FXR1_HUMAN-Phosphotyrosine477 relationship: transforms_into CCO:B0031320 ! FXR1_HUMAN-Phosphotyrosine68 relationship: transforms_into CCO:B0048268 ! FXR1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0006141 name: FXYD6_HUMAN def: "FXYD domain-containing ion transport regulator 6 precursor" [UniProtKB:Q9H0Q3] xref: EMBL:AAH18652.1 xref: EMBL:AAH93040.1 xref: EMBL:AAP35363.1 xref: EMBL:AAQ89335.1 xref: EMBL:CAB66634.1 xref: EMBL:CAG38488.1 xref: EMBL:CAI46171.1 xref: UniProtKB:Q6FIG9 xref: UniProtKB:Q6UW52 xref: UniProtKB:Q9H0Q3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004665 ! FXYD6_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008108 ! fxyd6-tp53 physical interaction relationship: participates_in CCO:I0019724 ! fxyd6-tle1 physical interaction relationship: participates_in CCO:I0019923 ! bcar1-fxyd6 physical interaction relationship: participates_in CCO:I0020007 ! fxyd6-gdf9 physical interaction relationship: participates_in CCO:I0020323 ! fxyd6-rfp physical interaction [Term] id: CCO:B0006142 name: GBB5_HUMAN def: "Guanine nucleotide-binding protein subunit beta-5" [UniProtKB:O14775] synonym: "Gbeta5" EXACT [UniProtKB:O14775] synonym: "Transducin beta chain 5" EXACT [UniProtKB:O14775] xref: EMBL:AAC63826.1 xref: EMBL:AAG18444.1 xref: EMBL:AAH13997.1 xref: EMBL:AAM15921.1 xref: UniProtKB:O14775 xref: UniProtKB:Q9HAU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004686 ! GNB5_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:I0008109 ! gnb5-mcm2 physical interaction relationship: participates_in CCO:I0020324 ! gnb5-mvd physical interaction relationship: participates_in CCO:I0020565 ! gnb5-eif3s1 physical interaction relationship: participates_in CCO:I0020566 ! gnb5-nr6a1 physical interaction relationship: participates_in CCO:I0020613 ! olfm2-gnb5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006143 name: GPDA_HUMAN def: "Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic" [UniProtKB:P21695] synonym: "EC 1.1.1.8" EXACT [UniProtKB:P21695] synonym: "GPD-C" EXACT [UniProtKB:P21695] synonym: "GPDH-C" EXACT [UniProtKB:P21695] xref: EMBL:AAA35925.1 xref: EMBL:AAA92863.1 xref: EMBL:AAH32234.1 xref: UniProtKB:P21695 xref: UniProtKB:Q8N1B0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004722 ! GPD1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000786 ! glycerol-3-phosphate dehydrogenase (NAD+) activity relationship: has_function CCO:F0000787 ! glycerol-3-phosphate dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0007988 ! coenzyme binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000579 ! glycerol-3-phosphate dehydrogenase complex relationship: participates_in CCO:I0008110 ! gpd1-ptn physical interaction [Term] id: CCO:B0006144 name: GSTM4_HUMAN def: "Glutathione S-transferase Mu 4" [UniProtKB:Q03013] synonym: "EC 2.5.1.18" EXACT [UniProtKB:Q03013] synonym: "GST class-mu 4" EXACT [UniProtKB:Q03013] synonym: "GSTM4-4" EXACT [UniProtKB:Q03013] synonym: "GTS-Mu2" EXACT [UniProtKB:Q03013] xref: EMBL:AAA57346.1 xref: EMBL:AAA57347.1 xref: EMBL:AAA58623.1 xref: EMBL:AAH15513.1 xref: EMBL:AAI08730.1 xref: EMBL:CAA40167.1 xref: EMBL:CAA48637.1 xref: EMBL:CAG46667.1 xref: UniProtKB:Q03013 xref: UniProtKB:Q05465 xref: UniProtKB:Q32NC1 xref: UniProtKB:Q6FH87 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004736 ! GSTM4_human relationship: has_function CCO:F0000783 ! glutathione transferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008113 ! gstm4-rif1 physical interaction relationship: participates_in CCO:I0008114 ! gstm4-tp53 physical interaction relationship: participates_in CCO:I0019726 ! gstm4-tle1 physical interaction relationship: participates_in CCO:I0020016 ! gstm4-aplp1 physical interaction relationship: participates_in CCO:I0020017 ! gstm4-med31 physical interaction relationship: participates_in CCO:I0020193 ! th1l-gstm4 physical interaction [Term] id: CCO:B0006145 name: GSTP1_HUMAN def: "Glutathione S-transferase P" [UniProtKB:P09211] synonym: "EC 2.5.1.18" EXACT [UniProtKB:P09211] synonym: "GST class-pi" EXACT [UniProtKB:P09211] synonym: "GSTP1-1" EXACT [UniProtKB:P09211] xref: EMBL:AAA56823.1 xref: EMBL:AAA64919.1 xref: EMBL:AAC13869.1 xref: EMBL:AAC51237.1 xref: EMBL:AAC51280.1 xref: EMBL:AAH10915.1 xref: EMBL:AAP72967.1 xref: EMBL:AAV38752.1 xref: EMBL:AAV38753.1 xref: EMBL:CAA29794.1 xref: EMBL:CAA30847.1 xref: EMBL:CAA30894.1 xref: EMBL:CAA33508.1 xref: EMBL:CAG29357.1 xref: UniProtKB:O00460 xref: UniProtKB:P09211 xref: UniProtKB:Q15690 xref: UniProtKB:Q5TZY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004737 ! GSTP1_human relationship: has_function CCO:F0000783 ! glutathione transferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008115 ! gstp1-ptn physical interaction relationship: participates_in CCO:I0017414 ! gstp1-traf2-2 physical interaction relationship: participates_in CCO:I0017415 ! gstp1-traf2-4 physical interaction relationship: participates_in CCO:I0018245 ! gstp1-jnk1 physical interaction relationship: participates_in CCO:I0018246 ! gstp1-mapk13 physical interaction relationship: participates_in CCO:I0018247 ! gstp1-traf2 physical interaction relationship: participates_in CCO:I0018883 ! gstp1-traf2-3 physical interaction relationship: participates_in CCO:I0020018 ! gstp1-loc56902 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0039450 ! GSTP1_HUMAN-Phosphotyrosine109 [Term] id: CCO:B0006147 name: HA23_HUMAN def: "HLA class II histocompatibility antigen, DQ(3) alpha chain precursor" [UniProtKB:P01909] synonym: "DC-alpha" EXACT [UniProtKB:P01909] synonym: "HLA-DCA" EXACT [UniProtKB:P01909] synonym: "HLA-DQA1*05011" EXACT [UniProtKB:P01909] synonym: "HLA-DQA1*0502" EXACT [UniProtKB:P01909] xref: EMBL:AAA35772.1 xref: EMBL:AAA59774.1 xref: EMBL:AAB60341.1 xref: EMBL:AAB91990.1 xref: EMBL:AAH08585.1 xref: EMBL:CAB06491.1 xref: UniProtKB:O19630 xref: UniProtKB:P01909 xref: UniProtKB:Q30101 xref: UniProtKB:Q9UM31 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004776 ! HLA-DQA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008117 ! hla_dqa1-rif1 physical interaction relationship: participates_in CCO:I0019732 ! hla_dqa1-tle1 physical interaction relationship: participates_in CCO:I0020022 ! hla_dqa1-aplp1 physical interaction relationship: participates_in CCO:I0020023 ! hla_dqa1-sh3gl2 physical interaction [Term] id: CCO:B0006148 name: HMOX2_HUMAN def: "Heme oxygenase 2" [UniProtKB:P30519] synonym: "EC 1.14.99.3" EXACT [UniProtKB:P30519] synonym: "HO-2" EXACT [UniProtKB:P30519] xref: EMBL:AAB22110.2 xref: EMBL:AAC05297.1 xref: EMBL:AAH02396.1 xref: EMBL:AAV28730.1 xref: EMBL:AAV38591.1 xref: EMBL:BAA04789.1 xref: UniProtKB:O60605 xref: UniProtKB:P30519 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004813 ! HMOX2_human relationship: has_function CCO:F0000804 ! heme oxygenase (decyclizing) activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0008120 ! hmox2-rif1 physical interaction relationship: participates_in CCO:I0019734 ! hmox2-med31 physical interaction relationship: participates_in CCO:I0019735 ! hmox2-git1 physical interaction relationship: participates_in CCO:I0020027 ! hmox2-setdb1 physical interaction [Term] id: CCO:B0006149 name: ID2_HUMAN def: "DNA-binding protein inhibitor ID-2" [UniProtKB:Q02363] synonym: "Inhibitor of DNA binding 2" EXACT [UniProtKB:Q02363] xref: EMBL:AAA58681.1 xref: EMBL:AAH30639.1 xref: EMBL:BAA02990.1 xref: UniProtKB:Q02363 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004848 ! ID2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008125 ! id2-rif1 physical interaction relationship: participates_in CCO:I0019743 ! id2-unc119 physical interaction relationship: participates_in CCO:I0020338 ! id2-dkfzp564o0523 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002465 ! positive regulation of macrophage differentiation [Term] id: CCO:B0006150 name: LC7L2_HUMAN def: "Putative RNA-binding protein Luc7-like 2" [UniProtKB:Q9Y383] xref: EMBL:AAD34054.1 xref: EMBL:AAD34069.1 xref: EMBL:AAH17163.1 xref: EMBL:AAH42625.1 xref: EMBL:AAH50708.1 xref: EMBL:AAH56886.1 xref: EMBL:BAA91713.1 xref: EMBL:BAA91737.1 xref: EMBL:BAB14297.1 xref: UniProtKB:Q8IUP9 xref: UniProtKB:Q9NVL3 xref: UniProtKB:Q9NVN7 xref: UniProtKB:Q9UQN1 xref: UniProtKB:Q9Y383 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004973 ! LUC7L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008129 ! luc7l2-ptn physical interaction relationship: participates_in CCO:I0008279 ! nasp-luc7l2 physical interaction relationship: participates_in CCO:I0016046 ! gadd45g-luc7l2 physical interaction relationship: participates_in CCO:I0019694 ! cdk5rap2-luc7l2 physical interaction relationship: participates_in CCO:I0019758 ! luc7l2-chd3 physical interaction relationship: participates_in CCO:I0019873 ! ulk2-luc7l2 physical interaction relationship: participates_in CCO:I0019891 ! alb-luc7l2 physical interaction relationship: participates_in CCO:I0019920 ! atrx-luc7l2 physical interaction relationship: participates_in CCO:I0020359 ! luc7l2-pea15 physical interaction relationship: participates_in CCO:I0020469 ! svil-luc7l2 physical interaction relationship: transforms_into CCO:B0012683 ! LC7L2_HUMAN-Phosphothreonine17 relationship: transforms_into CCO:B0012684 ! LC7L2_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0012685 ! LC7L2_HUMAN-Phosphothreonine111 relationship: transforms_into CCO:B0012686 ! LC7L2_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0012687 ! LC7L2_HUMAN-Phosphoserine358 relationship: transforms_into CCO:B0012688 ! LC7L2_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0012689 ! LC7L2_HUMAN-Phosphoserine384 [Term] id: CCO:B0006151 name: PDIA1_HUMAN def: "Protein disulfide-isomerase precursor" [UniProtKB:P07237] synonym: "Cellular thyroid hormone-binding protein" EXACT [UniProtKB:P07237] synonym: "EC 5.3.4.1" EXACT [UniProtKB:P07237] synonym: "p55" EXACT [UniProtKB:P07237] synonym: "PDI" EXACT [UniProtKB:P07237] synonym: "Prolyl 4-hydroxylase subunit beta" EXACT [UniProtKB:P07237] xref: EMBL:AAA61169.1 xref: EMBL:AAB22262.2 xref: EMBL:AAC13652.1 xref: EMBL:AAH10859.1 xref: EMBL:AAH29617.1 xref: EMBL:AAH71892.1 xref: EMBL:CAA28775.1 xref: EMBL:CAA30112.1 xref: UniProtKB:P07237 xref: UniProtKB:P30037 xref: UniProtKB:P32079 xref: UniProtKB:Q15205 xref: UniProtKB:Q6LDE5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005290 ! P4HB_human relationship: has_function CCO:F0000320 ! protein disulfide isomerase activity relationship: has_function CCO:F0001029 ! procollagen-proline 4-dioxygenase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0008139 ! p4hb-ptn physical interaction [Term] id: CCO:B0006152 name: PDCD5_HUMAN def: "Programmed cell death protein 5" [UniProtKB:O14737] synonym: "Protein TFAR19" EXACT [UniProtKB:O14737] synonym: "TF-1 cell apoptosis-related protein 19" EXACT [UniProtKB:O14737] xref: EMBL:AAD11579.1 xref: EMBL:AAH15519.1 xref: EMBL:AAP35340.1 xref: EMBL:CAG33215.1 xref: UniProtKB:O14737 xref: UniProtKB:Q53YC9 xref: UniProtKB:Q6IB70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005285 ! PDCD5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008141 ! pdcd5-rif1 physical interaction relationship: participates_in CCO:I0019607 ! pdcd5-eef1g physical interaction relationship: participates_in CCO:I0019782 ! pdcd5-htatip physical interaction relationship: participates_in CCO:I0019783 ! pdcd5-kiaa1377 physical interaction relationship: participates_in CCO:I0019784 ! pdcd5-utp14a physical interaction relationship: participates_in CCO:I0020097 ! pdcd5-acp5 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0013454 ! PDCD5_HUMAN-Phosphoserine119 [Term] id: CCO:B0006153 name: HAP1_HUMAN def: "Huntingtin-associated protein 1" [UniProtKB:P54257] synonym: "HAP-1" EXACT [UniProtKB:P54257] synonym: "Neuroan 1" EXACT [UniProtKB:P54257] xref: EMBL:AAC39861.1 xref: EMBL:AAC50297.1 xref: EMBL:BAB13952.1 xref: EMBL:CAB82785.1 xref: EMBL:CAC09418.1 xref: UniProtKB:O75358 xref: UniProtKB:P54257 xref: UniProtKB:Q9H4G3 xref: UniProtKB:Q9HA98 xref: UniProtKB:Q9NY90 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004777 ! HAP1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:I0008144 ! pfdn1-hap1 physical interaction relationship: participates_in CCO:I0019173 ! tbp-hap1 physical interaction relationship: participates_in CCO:I0019692 ! cdk5rap2-hap1 physical interaction relationship: participates_in CCO:I0019884 ! znf24-hap1 physical interaction relationship: participates_in CCO:I0019940 ! cbx8-hap1 physical interaction relationship: participates_in CCO:I0019962 ! crip1-hap1 physical interaction relationship: participates_in CCO:I0020075 ! mpp3-hap1 physical interaction relationship: participates_in CCO:I0020099 ! pdcd7-hap1 physical interaction relationship: participates_in CCO:I0020218 ! znf20-hap1 physical interaction relationship: participates_in CCO:I0020301 ! eif3s6-hap1 physical interaction relationship: participates_in CCO:I0020498 ! znf11b-hap1 physical interaction [Term] id: CCO:B0006154 name: PROF1_HUMAN def: "Profilin-1" [UniProtKB:P07737] synonym: "Profilin I" EXACT [UniProtKB:P07737] xref: EMBL:AAA36486.1 xref: EMBL:AAH02475.1 xref: EMBL:AAH06768.1 xref: EMBL:AAH13439.1 xref: EMBL:AAH15164.1 xref: EMBL:AAH57828.1 xref: UniProtKB:P07737 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005380 ! PFN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008148 ! pfn1-rif1 physical interaction relationship: participates_in CCO:I0008289 ! pfn1-dlg5 physical interaction relationship: participates_in CCO:I0019785 ! pfn1-crmp1 physical interaction relationship: participates_in CCO:I0019786 ! pfn1-unc119 physical interaction relationship: participates_in CCO:I0020105 ! pfn1-c14orf1 physical interaction relationship: participates_in CCO:I0020106 ! pfn1-tle1 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0013613 ! PROF1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013614 ! PROF1_HUMAN-N6-acetyllysine105 relationship: transforms_into CCO:B0013615 ! PROF1_HUMAN-Phosphotyrosine129 [Term] id: CCO:B0006155 name: PROF2_HUMAN def: "Profilin-2" [UniProtKB:P35080] synonym: "Profilin II" EXACT [UniProtKB:P35080] xref: EMBL:AAA03022.1 xref: EMBL:AAG24949.1 xref: EMBL:AAH18049.1 xref: EMBL:AAH43646.1 xref: UniProtKB:P35080 xref: UniProtKB:Q8WVF9 xref: UniProtKB:Q9HBK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005381 ! PFN2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001669 ! phosphatidylinositol-4,5-bisphosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:I0008151 ! sept5-pfn2 physical interaction relationship: participates_in CCO:I0008173 ! terf1-pfn2 physical interaction relationship: participates_in CCO:I0016078 ! hd-pfn2 physical interaction relationship: participates_in CCO:I0016079 ! hd-pfn2-1 physical interaction relationship: participates_in CCO:I0016080 ! hd-pfn2-2 physical interaction relationship: participates_in CCO:I0018159 ! pfn2-hd physical interaction relationship: participates_in CCO:I0018844 ! golgb1-pfn2-1 physical interaction relationship: participates_in CCO:I0019278 ! muc7-pfn2 physical interaction relationship: participates_in CCO:I0019558 ! actg1-pfn2 physical interaction relationship: participates_in CCO:I0019585 ! eef1a1-pfn2 physical interaction relationship: participates_in CCO:I0019622 ! sgta-pfn2 physical interaction relationship: participates_in CCO:I0019818 ! rps10-pfn2 physical interaction relationship: participates_in CCO:I0019970 ! dlst-pfn2 physical interaction relationship: participates_in CCO:I0020012 ! golgb1-pfn2 physical interaction relationship: participates_in CCO:I0020035 ! dkfzp434n1418-pfn2 physical interaction relationship: participates_in CCO:I0020040 ! ik-pfn2 physical interaction relationship: participates_in CCO:I0020068 ! c16orf24-pfn2 physical interaction relationship: participates_in CCO:I0020083 ! ndufb8-pfn2 physical interaction relationship: participates_in CCO:I0020113 ! plaur-pfn2 physical interaction relationship: participates_in CCO:I0020133 ! ptprs-pfn2 physical interaction relationship: participates_in CCO:I0020213 ! wdr33-pfn2 physical interaction relationship: participates_in CCO:I0020431 ! rap1ga1-pfn2 physical interaction relationship: participates_in CCO:I0020438 ! rnf146-pfn2 physical interaction relationship: participates_in CCO:I0020560 ! flt3lg-pfn2 physical interaction relationship: participates_in CCO:P0000811 ! regulation of actin polymerization and/or depolymerization relationship: transforms_into CCO:B0013616 ! PROF2_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0031368 ! PROF2_HUMAN-Phosphotyrosine99 [Term] id: CCO:B0006157 name: PSG9_HUMAN def: "Pregnancy-specific beta-1-glycoprotein 9 precursor" [UniProtKB:Q00887] synonym: "Pregnancy-specific beta-1 glycoprotein B" EXACT [UniProtKB:Q00887] synonym: "Pregnancy-specific glycoprotein 7" EXACT [UniProtKB:Q00887] synonym: "Pregnancy-specific glycoprotein 9" EXACT [UniProtKB:Q00887] synonym: "PS-beta-B" EXACT [UniProtKB:Q00887] synonym: "PS34" EXACT [UniProtKB:Q00887] synonym: "PSBG-9" EXACT [UniProtKB:Q00887] synonym: "PSG7" EXACT [UniProtKB:Q00887] xref: EMBL:AAA52605.1 xref: EMBL:AAA60203.1 xref: EMBL:AAA63251.1 xref: EMBL:AAA63252.1 xref: EMBL:AAA74512.1 xref: EMBL:AAA78266.1 xref: EMBL:AAD21023.1 xref: EMBL:AAH20759.1 xref: EMBL:CAA35612.1 xref: UniProtKB:Q00887 xref: UniProtKB:Q15236 xref: UniProtKB:Q15237 xref: UniProtKB:Q8WW78 xref: UniProtKB:Q9UQ73 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005389 ! PSG9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0008154 ! psg9-rif1 physical interaction [Term] id: CCO:B0006158 name: DDR1_HUMAN def: "Epithelial discoidin domain-containing receptor 1 precursor" [UniProtKB:Q08345] synonym: "CD167 antigen-like family member A" EXACT [UniProtKB:Q08345] synonym: "CD167a antigen" EXACT [UniProtKB:Q08345] synonym: "Cell adhesion kinase" EXACT [UniProtKB:Q08345] synonym: "Discoidin receptor tyrosine kinase" EXACT [UniProtKB:Q08345] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q08345] synonym: "Epithelial discoidin domain receptor 1" EXACT [UniProtKB:Q08345] synonym: "HGK2" EXACT [UniProtKB:Q08345] synonym: "Protein-tyrosine kinase RTK 6" EXACT [UniProtKB:Q08345] synonym: "TRK E" EXACT [UniProtKB:Q08345] synonym: "Tyrosine kinase DDR" EXACT [UniProtKB:Q08345] synonym: "Tyrosine-protein kinase CAK" EXACT [UniProtKB:Q08345] xref: EMBL:AAA02866.1 xref: EMBL:AAA18019.1 xref: EMBL:AAB05208.1 xref: EMBL:AAC50917.1 xref: EMBL:AAH08716.1 xref: EMBL:AAH13400.1 xref: EMBL:BAB63318.1 xref: EMBL:CAA52915.1 xref: EMBL:CAA66871.1 xref: EMBL:CAA82335.1 xref: EMBL:CAI17434.1 xref: EMBL:CAI18441.1 xref: EMBL:CAI18450.1 xref: EMBL:CAI18534.1 xref: UniProtKB:Q08345 xref: UniProtKB:Q14196 xref: UniProtKB:Q16562 xref: UniProtKB:Q5ST12 xref: UniProtKB:Q9UD37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004453 ! DDR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008157 ! rgs2-ddr1 physical interaction relationship: participates_in CCO:I0019580 ! ddr1-snapap physical interaction relationship: participates_in CCO:I0019581 ! ddr1-ttr physical interaction relationship: participates_in CCO:I0019861 ! tm4sf1-ddr1 physical interaction relationship: participates_in CCO:I0020284 ! ddr1-wdr57 physical interaction relationship: participates_in CCO:I0020536 ! ddr1-c1orf165 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0011459 ! DDR1_HUMAN-Phosphotyrosine513 relationship: transforms_into CCO:B0011460 ! DDR1_HUMAN-Phosphotyrosine792 relationship: transforms_into CCO:B0011461 ! DDR1_HUMAN-Phosphotyrosine796 relationship: transforms_into CCO:B0011462 ! DDR1_HUMAN-Phosphotyrosine797 [Term] id: CCO:B0006159 name: S10A8_HUMAN def: "Protein S100-A8" [UniProtKB:P05109] synonym: "Calgranulin-A" EXACT [UniProtKB:P05109] synonym: "Calprotectin L1L subunit" EXACT [UniProtKB:P05109] synonym: "CFAG" EXACT [UniProtKB:P05109] synonym: "Cystic fibrosis antigen" EXACT [UniProtKB:P05109] synonym: "Leukocyte L1 complex light chain" EXACT [UniProtKB:P05109] synonym: "Migration inhibitory factor-related protein 8" EXACT [UniProtKB:P05109] synonym: "MRP-8" EXACT [UniProtKB:P05109] synonym: "P8" EXACT [UniProtKB:P05109] synonym: "S100 calcium-binding protein A8" EXACT [UniProtKB:P05109] synonym: "Urinary stone protein band A" EXACT [UniProtKB:P05109] xref: EMBL:AAA36327.1 xref: EMBL:AAH05928.1 xref: EMBL:AAP36042.1 xref: EMBL:CAA29580.1 xref: EMBL:CAA68390.1 xref: EMBL:CAG28602.1 xref: EMBL:CAI19497.1 xref: UniProtKB:P05109 xref: UniProtKB:Q5SY70 xref: UniProtKB:Q9UC92 xref: UniProtKB:Q9UCJ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005553 ! S100A8_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008159 ! s100a8-rif1 physical interaction relationship: participates_in CCO:I0008319 ! s100a8-tp53 physical interaction relationship: participates_in CCO:I0016391 ! nfkbib-s100a8 physical interaction relationship: participates_in CCO:I0016727 ! map3k3-s100a8 physical interaction relationship: participates_in CCO:I0020161 ! s100a8-gdf9 physical interaction relationship: participates_in CCO:I0020447 ! s100a8-hrmt1l2 physical interaction relationship: participates_in CCO:I0020662 ! s100a8-rab17 physical interaction [Term] id: CCO:B0006160 name: SAS10_HUMAN def: "Something about silencing protein 10" [UniProtKB:Q9NQZ2] synonym: "Charged amino acid-rich leucine zipper 1" EXACT [UniProtKB:Q9NQZ2] synonym: "CRL1" EXACT [UniProtKB:Q9NQZ2] synonym: "Disrupter of silencing SAS10" EXACT [UniProtKB:Q9NQZ2] synonym: "UTP3 homolog" EXACT [UniProtKB:Q9NQZ2] xref: EMBL:AAF91408.1 xref: EMBL:AAH04546.1 xref: EMBL:BAB15588.1 xref: EMBL:CAB66525.1 xref: EMBL:CAG38575.1 xref: UniProtKB:Q6FI82 xref: UniProtKB:Q9NQZ2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005563 ! UTP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008160 ! crlz1-ptn physical interaction relationship: participates_in CCO:I0019820 ! crlz1-zhx1 physical interaction relationship: transforms_into CCO:B0013957 ! SAS10_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0013958 ! SAS10_HUMAN-Phosphoserine150 relationship: transforms_into CCO:B0013959 ! SAS10_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0013960 ! SAS10_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0070319 ! SAS10_HUMAN-Phosphothreonine362 [Term] id: CCO:B0006161 name: SFPQ_HUMAN def: "Splicing factor, proline- and glutamine-rich" [UniProtKB:P23246] synonym: "100 kDa DNA-pairing protein" EXACT [UniProtKB:P23246] synonym: "DNA-binding p52/p100 complex, 100 kDa subunit" EXACT [UniProtKB:P23246] synonym: "hPOMp100" EXACT [UniProtKB:P23246] synonym: "Polypyrimidine tract-binding protein-associated-splicing factor" EXACT [UniProtKB:P23246] synonym: "PSF" EXACT [UniProtKB:P23246] synonym: "PTB-associated-splicing factor" EXACT [UniProtKB:P23246] xref: EMBL:CAA34747.1 xref: EMBL:CAA50283.1 xref: EMBL:CAI12467.1 xref: EMBL:EAX07426.1 xref: UniProtKB:P23246 xref: UniProtKB:P30808 xref: UniProtKB:Q5SZ71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005599 ! SFPQ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0008162 ! sfpq-rps27a physical interaction relationship: participates_in CCO:I0008163 ! rps27a-sfpq physical interaction relationship: participates_in CCO:I0016120 ! sfpq-ptbp1-1 physical interaction relationship: participates_in CCO:I0016121 ! snrpa-sfpq-1 physical interaction relationship: participates_in CCO:I0016415 ! nfkbib-sfpq physical interaction relationship: participates_in CCO:I0016429 ! nfkbie-sfpq physical interaction relationship: participates_in CCO:I0016823 ! nfkb2-sfpq physical interaction relationship: participates_in CCO:I0016848 ! map3k14-sfpq physical interaction relationship: participates_in CCO:I0016883 ! relb-sfpq physical interaction relationship: participates_in CCO:I0016976 ! tbk1-sfpq physical interaction relationship: participates_in CCO:I0017107 ! traf1-sfpq physical interaction relationship: participates_in CCO:I0017313 ! exosc5-sfpq physical interaction relationship: participates_in CCO:I0018056 ! sin3a-sfpq-1 physical interaction relationship: participates_in CCO:I0018503 ! snrpa-sfpq-4 physical interaction relationship: participates_in CCO:I0018827 ! snrpa-sfpq-3 physical interaction relationship: participates_in CCO:I0019252 ! sin3a-sfpq-2 physical interaction relationship: participates_in CCO:I0019497 ! snrpa-sfpq-2 physical interaction relationship: participates_in CCO:I0020168 ! sfpq-sfpq physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0014026 ! SFPQ_HUMAN-Omega-N-methylated arginine7 relationship: transforms_into CCO:B0014027 ! SFPQ_HUMAN-Omega-N-methylated arginine9 relationship: transforms_into CCO:B0014028 ! SFPQ_HUMAN-Omega-N-methylated arginine19 relationship: transforms_into CCO:B0014029 ! SFPQ_HUMAN-Omega-N-methylated arginine25 relationship: transforms_into CCO:B0014030 ! SFPQ_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0070397 ! SFPQ_HUMAN-Phosphothreonine687 [Term] id: CCO:B0006162 name: SOCS3_HUMAN def: "Suppressor of cytokine signaling 3" [UniProtKB:O14543] synonym: "CIS-3" EXACT [UniProtKB:O14543] synonym: "Cytokine-inducible SH2 protein 3" EXACT [UniProtKB:O14543] synonym: "SOCS-3" EXACT [UniProtKB:O14543] synonym: "SSI-3" EXACT [UniProtKB:O14543] synonym: "STAT-induced STAT inhibitor 3" EXACT [UniProtKB:O14543] xref: EMBL:AAD42231.1 xref: EMBL:AAH60858.1 xref: EMBL:BAA22430.1 xref: EMBL:BAA22537.1 xref: UniProtKB:O14509 xref: UniProtKB:O14543 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005648 ! SOCS3_human relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008165 ! socs3-pin1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0002705 ! negative regulation of insulin receptor signaling pathway [Term] id: CCO:B0006163 name: SSRA_HUMAN def: "Translocon-associated protein subunit alpha precursor" [UniProtKB:P43307] synonym: "Signal sequence receptor subunit alpha" EXACT [UniProtKB:P43307] synonym: "SSR-alpha" EXACT [UniProtKB:P43307] synonym: "TRAP-alpha" EXACT [UniProtKB:P43307] xref: EMBL:AAD48778.1 xref: EMBL:AAH07710.1 xref: EMBL:AAP36051.1 xref: EMBL:BAC11701.1 xref: EMBL:BAD96482.1 xref: EMBL:BAD96529.1 xref: EMBL:BAF84239.1 xref: EMBL:CAA78290.1 xref: EMBL:CAG33242.1 xref: EMBL:CAI16444.1 xref: UniProtKB:A8K685 xref: UniProtKB:P43307 xref: UniProtKB:Q53GX2 xref: UniProtKB:Q53H19 xref: UniProtKB:Q5TAM3 xref: UniProtKB:Q6IB43 xref: UniProtKB:Q8NBH9 xref: UniProtKB:Q96IA2 xref: UniProtKB:Q9TNQ8 xref: UniProtKB:Q9UN49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005675 ! SSR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008167 ! ssr1-ptn physical interaction relationship: participates_in CCO:I0008324 ! ssr1-dkc1 physical interaction relationship: participates_in CCO:I0019842 ! ssr1-eef1a1 physical interaction relationship: participates_in CCO:I0020175 ! ssr1-utp14a physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0014218 ! SSRA_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0070939 ! SSRA_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0070940 ! SSRA_HUMAN-Phosphothreonine260 [Term] id: CCO:B0006164 name: STX5_HUMAN def: "Syntaxin-5" [UniProtKB:Q13190] xref: EMBL:AAC71078.1 xref: EMBL:AAH02645.1 xref: EMBL:AAH12137.2 xref: EMBL:AAV38452.1 xref: EMBL:AAV38453.1 xref: EMBL:CAD97668.1 xref: UniProtKB:Q13190 xref: UniProtKB:Q5U0D4 xref: UniProtKB:Q7Z3T6 xref: UniProtKB:Q9BUG1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005701 ! STX5_human relationship: has_function CCO:F0001631 ! SNAP receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001141 ! SNARE complex relationship: located_in CCO:C0001534 ! ER-Golgi intermediate compartment membrane relationship: participates_in CCO:I0008168 ! stx5a-tp53 physical interaction relationship: participates_in CCO:I0008326 ! stx5a-rif1 physical interaction relationship: participates_in CCO:I0020178 ! stx5a-aplp1 physical interaction [Term] id: CCO:B0006166 name: KIF5A_HUMAN def: "Kinesin heavy chain isoform 5A" [UniProtKB:Q12840] synonym: "Kinesin heavy chain neuron-specific 1" EXACT [UniProtKB:Q12840] synonym: "Neuronal kinesin heavy chain" EXACT [UniProtKB:Q12840] synonym: "NKHC" EXACT [UniProtKB:Q12840] xref: EMBL:AAA20231.1 xref: EMBL:BAE06127.1 xref: UniProtKB:Q12840 xref: UniProtKB:Q4LE26 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004950 ! KIF5A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0001625 ! ciliary rootlet relationship: located_in CCO:C0001707 ! neuron projection relationship: participates_in CCO:I0008179 ! tp53bp2-kif5a physical interaction relationship: participates_in CCO:I0019752 ! itsn1-kif5a physical interaction [Term] id: CCO:B0006167 name: TBB4_HUMAN def: "Tubulin beta-4 chain" [UniProtKB:P04350] synonym: "Tubulin 5 beta" EXACT [UniProtKB:P04350] xref: EMBL:AAH06570.1 xref: EMBL:AAH13683.1 xref: EMBL:CAA25318.1 xref: UniProtKB:P04350 xref: UniProtKB:Q969E5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005736 ! TUBB4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0008183 ! tubb4-khdrbs1 physical interaction relationship: participates_in CCO:I0008513 ! tubb4-lig1 physical interaction relationship: participates_in CCO:I0019871 ! tubb4-tf physical interaction relationship: participates_in CCO:I0020210 ! tubb4-arhgef7 physical interaction relationship: participates_in CCO:I0020489 ! tubb4-insm1 physical interaction relationship: participates_in CCO:I0020490 ! tubb4-mrpl28 physical interaction relationship: participates_in CCO:I0020491 ! tubb4-robo1 physical interaction relationship: transforms_into CCO:B0014315 ! TBB4_HUMAN-Phosphothreonine290 relationship: transforms_into CCO:B0014316 ! TBB4_HUMAN-Phosphothreonine366 relationship: transforms_into CCO:B0031379 ! TBB4_HUMAN-Phosphotyrosine36 [Term] id: CCO:B0006168 name: IGS21_HUMAN def: "Immunoglobulin superfamily member 21 precursor" [UniProtKB:Q96ID5] xref: EMBL:AAH07618.1 xref: EMBL:BAC11542.1 xref: EMBL:CAH70256.1 xref: EMBL:CAH70900.1 xref: EMBL:CAH71695.1 xref: EMBL:CAI22205.1 xref: UniProtKB:Q8NBR8 xref: UniProtKB:Q96ID5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004870 ! IGSF21_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0008185 ! ube2v2-igsf21 physical interaction relationship: participates_in CCO:I0008261 ! mad2l1bp-igsf21 physical interaction relationship: participates_in CCO:I0019831 ! serpinb9-igsf21 physical interaction relationship: participates_in CCO:I0019892 ! anxa3-igsf21 physical interaction relationship: participates_in CCO:I0019914 ! atf3-igsf21 physical interaction relationship: participates_in CCO:I0019926 ! bcr-igsf21 physical interaction relationship: participates_in CCO:I0020030 ! hrmt1l2-igsf21 physical interaction relationship: participates_in CCO:I0020031 ! hspb1-igsf21 physical interaction relationship: participates_in CCO:I0020199 ! tmsb4x-igsf21 physical interaction relationship: participates_in CCO:I0020260 ! c5orf13-igsf21 physical interaction relationship: participates_in CCO:I0020290 ! dgkd-igsf21 physical interaction [Term] id: CCO:B0006169 name: WDR33_HUMAN def: "WD repeat-containing protein 33" [UniProtKB:Q9C0J8] synonym: "WD repeat-containing protein WDC146" EXACT [UniProtKB:Q9C0J8] xref: EMBL:AAX82033.1 xref: EMBL:BAB32435.1 xref: EMBL:EAW95342.1 xref: UniProtKB:Q587J1 xref: UniProtKB:Q9C0J8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005918 ! WDR33_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008187 ! wdr33-tp53 physical interaction relationship: participates_in CCO:I0019876 ! wdr33-git1 physical interaction relationship: participates_in CCO:I0019877 ! wdr33-hrmt1l2 physical interaction relationship: participates_in CCO:I0020212 ! wdr33-myst2 physical interaction relationship: participates_in CCO:I0020213 ! wdr33-pfn2 physical interaction relationship: participates_in CCO:I0020214 ! wdr33-sh3gl3 physical interaction relationship: participates_in CCO:I0020215 ! wdr33-zhx1 physical interaction relationship: transforms_into CCO:B0014674 ! WDR33_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0071835 ! WDR33_HUMAN-Phosphoserine1210 [Term] id: CCO:B0006170 name: Q5ZF45_HUMAN def: "KLEIP (Kelch-like ECT2 interacting protein)" [UniProtKB:Q5ZF45] xref: EMBL:CAH59617.1 xref: UniProtKB:Q5ZF45 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006004 ! KLHLX_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008188 ! klhlx-rif1 physical interaction relationship: participates_in CCO:I0008353 ! klhlx-pin1 physical interaction [Term] id: CCO:B0006171 name: Q6ICP4_HUMAN def: "ARHH protein (Ras homolog gene family, member H, isoform CRA_a) (cDNA, FLJ94345, Homo sapiens ras homolog gene family, member H (ARHH), mRNA)" [UniProtKB:Q6ICP4] xref: EMBL:BAG36484.1 xref: EMBL:CAG29345.1 xref: EMBL:EAW92960.1 xref: UniProtKB:Q6ICP4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006008 ! ARHH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008189 ! arhh-rif1 physical interaction relationship: participates_in CCO:I0020509 ! arhh-kcnh2 physical interaction [Term] id: CCO:B0006172 name: ARPC3_HUMAN def: "Actin-related protein 2/3 complex subunit 3" [UniProtKB:O15145] synonym: "Arp2/3 complex 21 kDa subunit" EXACT [UniProtKB:O15145] synonym: "p21-ARC" EXACT [UniProtKB:O15145] xref: EMBL:AAB61466.1 xref: EMBL:AAB64191.1 xref: EMBL:AAH67747.1 xref: EMBL:AAH78162.1 xref: EMBL:CAG28595.1 xref: UniProtKB:O00554 xref: UniProtKB:O15145 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004102 ! ARPC3_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000443 ! Arp2/3 protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008191 ! arpc3-cdkn2b physical interaction relationship: participates_in CCO:I0008358 ! arpc3-centd2 physical interaction relationship: participates_in CCO:I0018502 ! wasp-arp2-1 physical interaction relationship: participates_in CCO:I0019563 ! arpc3-bat3 physical interaction relationship: participates_in CCO:I0020211 ! u5_116kd-arpc3 physical interaction relationship: participates_in CCO:I0020237 ! arpc3-hrmt1l2 physical interaction relationship: participates_in CCO:I0020358 ! lgals4-arpc3 physical interaction relationship: participates_in CCO:I0020510 ! arpc3-cetp physical interaction relationship: participates_in CCO:I0020511 ! arpc3-lta4h physical interaction relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: transforms_into CCO:B0031294 ! ARPC3_HUMAN-Phosphotyrosine47 [Term] id: CCO:B0006173 name: WDR62_HUMAN def: "WD repeat-containing protein 62" [UniProtKB:O43379] xref: EMBL:AAC27979.1 xref: EMBL:AAH17261.1 xref: EMBL:BAC03488.1 xref: EMBL:CAH56191.1 xref: EMBL:CAH56390.1 xref: UniProtKB:O43379 xref: UniProtKB:Q63HP9 xref: UniProtKB:Q659D7 xref: UniProtKB:Q8NBF7 xref: UniProtKB:Q96AD9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005925 ! WDR62_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008205 ! c19orf14-rif1 physical interaction relationship: participates_in CCO:I0019931 ! c19orf14-tbp physical interaction relationship: transforms_into CCO:B0014677 ! WDR62_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0014678 ! WDR62_HUMAN-Phosphoserine987 relationship: transforms_into CCO:B0014679 ! WDR62_HUMAN-Phosphoserine992 relationship: transforms_into CCO:B0014680 ! WDR62_HUMAN-Phosphoserine995 relationship: transforms_into CCO:B0014681 ! WDR62_HUMAN-Phosphothreonine1053 relationship: transforms_into CCO:B0014682 ! WDR62_HUMAN-Phosphoserine1070 relationship: transforms_into CCO:B0014683 ! WDR62_HUMAN-Phosphoserine1093 relationship: transforms_into CCO:B0014684 ! WDR62_HUMAN-Phosphoserine1101 relationship: transforms_into CCO:B0014685 ! WDR62_HUMAN-Phosphoserine1228 relationship: transforms_into CCO:B0014686 ! WDR62_HUMAN-Phosphoserine1348 relationship: transforms_into CCO:B0014687 ! WDR62_HUMAN-Phosphoserine1405 relationship: transforms_into CCO:B0048425 ! WDR62_HUMAN-Phosphoserine1248 relationship: transforms_into CCO:B0048426 ! WDR62_HUMAN-Phosphoserine1249 [Term] id: CCO:B0006174 name: CG020_HUMAN def: "UPF0363 protein C7orf20" [UniProtKB:Q7L5D6] synonym: "Conserved edge-expressed protein" EXACT [UniProtKB:Q7L5D6] xref: EMBL:AAD27729.1 xref: EMBL:AAH03550.2 xref: EMBL:BAG51289.1 xref: EMBL:BAG53546.1 xref: EMBL:BAG54258.1 xref: EMBL:CAB61355.1 xref: EMBL:EAL23708.1 xref: UniProtKB:A4D2Q1 xref: UniProtKB:B3KNC7 xref: UniProtKB:Q7L5D6 xref: UniProtKB:Q9UFC9 xref: UniProtKB:Q9Y309 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004336 ! C7orf20_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0008207 ! c7orf20-plk1 physical interaction relationship: participates_in CCO:I0008365 ! c7orf20-cdkn1a physical interaction relationship: participates_in CCO:I0008452 ! c7orf20-ptms physical interaction relationship: participates_in CCO:I0019679 ! c7orf20-htatip physical interaction relationship: participates_in CCO:I0019934 ! c7orf20-capns1 physical interaction relationship: participates_in CCO:I0020262 ! c7orf20-prkcsh physical interaction relationship: participates_in CCO:I0020457 ! sncaip-c7orf20 physical interaction relationship: participates_in CCO:I0020523 ! c7orf20-sod2 physical interaction relationship: transforms_into CCO:B0041286 ! CG020_HUMAN-N-acetylalanine2 [Term] id: CCO:B0006175 name: CI082_HUMAN def: "Uncharacterized protein C9orf82" [UniProtKB:Q9H8G2] xref: EMBL:AAH14658.1 xref: EMBL:AAH71953.1 xref: EMBL:BAB14655.1 xref: EMBL:CAH72640.1 xref: UniProtKB:Q5VY32 xref: UniProtKB:Q6IPE6 xref: UniProtKB:Q96C59 xref: UniProtKB:Q9H8G2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004353 ! C9orf82_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008208 ! c9orf82-ptn physical interaction relationship: participates_in CCO:I0019936 ! c9orf82-myst2 physical interaction relationship: transforms_into CCO:B0011220 ! CI082_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0011221 ! CI082_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0011222 ! CI082_HUMAN-Phosphoserine312 [Term] id: CCO:B0006176 name: CACB4_HUMAN def: "Voltage-dependent L-type calcium channel subunit beta-4" [UniProtKB:O00305] synonym: "CAB4" EXACT [UniProtKB:O00305] synonym: "Calcium channel voltage-dependent subunit beta 4" EXACT [UniProtKB:O00305] xref: EMBL:AAB53333.1 xref: EMBL:AAC24206.1 xref: EMBL:AAH75049.1 xref: EMBL:AAL14351.1 xref: UniProtKB:O00305 xref: UniProtKB:O60515 xref: UniProtKB:Q6B000 xref: UniProtKB:Q96L40 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004207 ! CACNB4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008209 ! cacnb4-ptn physical interaction relationship: participates_in CCO:I0019937 ! cacnb4-med31 physical interaction relationship: participates_in CCO:I0020265 ! cacnb4-tbl3 physical interaction relationship: transforms_into CCO:B0010883 ! CACB4_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0010884 ! CACB4_HUMAN-Phosphothreonine405 relationship: transforms_into CCO:B0010885 ! CACB4_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0010886 ! CACB4_HUMAN-Phosphothreonine411 relationship: transforms_into CCO:B0010887 ! CACB4_HUMAN-Phosphoserine508 [Term] id: CCO:B0006177 name: CAD10_HUMAN def: "Cadherin-10 precursor" [UniProtKB:Q9Y6N8] synonym: "T2-cadherin" EXACT [UniProtKB:Q9Y6N8] xref: EMBL:AAD44017.1 xref: EMBL:BAA87417.1 xref: UniProtKB:Q9ULB3 xref: UniProtKB:Q9Y6N8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004208 ! CDH10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008210 ! cdh10-ptn physical interaction relationship: transforms_into CCO:B0065810 ! CAD10_HUMAN-Phosphoserine784 [Term] id: CCO:B0006178 name: CK5P2_HUMAN def: "CDK5 regulatory subunit-associated protein 2" [UniProtKB:Q96SN8] synonym: "CDK5 activator-binding protein C48" EXACT [UniProtKB:Q96SN8] synonym: "Centrosome-associated protein 215" EXACT [UniProtKB:Q96SN8] xref: EMBL:AAH04526.2 xref: EMBL:AAP41926.1 xref: EMBL:BAA91865.1 xref: EMBL:BAB13459.2 xref: EMBL:BAB15263.1 xref: EMBL:BAB55253.1 xref: EMBL:CAB61487.1 xref: EMBL:CAD97663.1 xref: EMBL:CAD97828.1 xref: UniProtKB:Q7Z3L4 xref: UniProtKB:Q7Z3U1 xref: UniProtKB:Q7Z7I6 xref: UniProtKB:Q96SN8 xref: UniProtKB:Q9BSW0 xref: UniProtKB:Q9H6J6 xref: UniProtKB:Q9HCD9 xref: UniProtKB:Q9NV90 xref: UniProtKB:Q9UIW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004359 ! CDK5RAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008211 ! cdk5rap2-ptn physical interaction relationship: participates_in CCO:I0019533 ! cdk5rap2-eef1g physical interaction relationship: participates_in CCO:I0019576 ! cdk5rap2-crmp1 physical interaction relationship: participates_in CCO:I0019577 ! cdk5rap2-dkfzp564o05 physical interaction relationship: participates_in CCO:I0019691 ! cdk5rap2-c14orf1 physical interaction relationship: participates_in CCO:I0019692 ! cdk5rap2-hap1 physical interaction relationship: participates_in CCO:I0019693 ! cdk5rap2-htatip physical interaction relationship: participates_in CCO:I0019694 ! cdk5rap2-luc7l2 physical interaction relationship: participates_in CCO:I0019944 ! cdk5rap2-mageh1 physical interaction relationship: participates_in CCO:I0019945 ! cdk5rap2-senp2 physical interaction relationship: participates_in CCO:I0019946 ! cdk5rap2-znf259 physical interaction relationship: participates_in CCO:I0020272 ! cdk5rap2-stard9 physical interaction relationship: participates_in CCO:I0020527 ! cdk5rap2-nefl physical interaction relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation relationship: transforms_into CCO:B0011227 ! CK5P2_HUMAN-Phosphotyrosine461 relationship: transforms_into CCO:B0011228 ! CK5P2_HUMAN-Phosphoserine466 relationship: transforms_into CCO:B0011229 ! CK5P2_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0011230 ! CK5P2_HUMAN-Phosphoserine815 relationship: transforms_into CCO:B0011231 ! CK5P2_HUMAN-Phosphoserine1074 relationship: transforms_into CCO:B0011232 ! CK5P2_HUMAN-Phosphoserine1238 relationship: transforms_into CCO:B0011233 ! CK5P2_HUMAN-Phosphoserine1548 relationship: transforms_into CCO:B0011234 ! CK5P2_HUMAN-Phosphoserine1556 relationship: transforms_into CCO:B0064362 ! CK5P2_HUMAN-Phosphoserine1887 relationship: transforms_into CCO:B0064363 ! CK5P2_HUMAN-Phosphoserine1893 [Term] id: CCO:B0006179 name: APLP1_HUMAN def: "Amyloid-like protein 1 precursor" [UniProtKB:P51693] synonym: "APLP" EXACT [UniProtKB:P51693] synonym: "APLP-1" EXACT [UniProtKB:P51693] xref: EMBL:AAB50173.1 xref: EMBL:AAB96331.1 xref: EMBL:AAH12889.1 xref: UniProtKB:O00113 xref: UniProtKB:P51693 xref: UniProtKB:Q96A92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004082 ! APLP1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008213 ! cdkn2c-aplp1 physical interaction relationship: participates_in CCO:I0008272 ! mphosph6-aplp1 physical interaction relationship: participates_in CCO:I0018840 ! aplp1-znf24-1 physical interaction relationship: participates_in CCO:I0019603 ! np-aplp1 physical interaction relationship: participates_in CCO:I0019712 ! eif2s2-aplp1 physical interaction relationship: participates_in CCO:I0019741 ! hspe1-aplp1 physical interaction relationship: participates_in CCO:I0019780 ! pcdha4-aplp1 physical interaction relationship: participates_in CCO:I0019821 ! sat-aplp1 physical interaction relationship: participates_in CCO:I0019855 ! tk1-aplp1 physical interaction relationship: participates_in CCO:I0019881 ! znf24-aplp1 physical interaction relationship: participates_in CCO:I0019894 ! aplp1-utp14a physical interaction relationship: participates_in CCO:I0020016 ! gstm4-aplp1 physical interaction relationship: participates_in CCO:I0020022 ! hla_dqa1-aplp1 physical interaction relationship: participates_in CCO:I0020080 ! naca-aplp1 physical interaction relationship: participates_in CCO:I0020178 ! stx5a-aplp1 physical interaction relationship: participates_in CCO:I0020198 ! tmsb4x-aplp1 physical interaction relationship: participates_in CCO:I0020400 ! phf10-aplp1 physical interaction relationship: participates_in CCO:I0020475 ! tcf21-aplp1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0006180 name: GDF9_HUMAN def: "Growth/differentiation factor 9 precursor" [UniProtKB:O60383] synonym: "GDF-9" EXACT [UniProtKB:O60383] xref: EMBL:AAC08450.1 xref: EMBL:AAH96228.1 xref: EMBL:AAH96229.1 xref: EMBL:AAH96230.1 xref: EMBL:AAH96231.1 xref: UniProtKB:O60383 xref: UniProtKB:Q4VAW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004691 ! GDF9_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0008215 ! cdkn2c-gdf9 physical interaction relationship: participates_in CCO:I0008240 ! smpd3-gdf9 physical interaction relationship: participates_in CCO:I0008251 ! ilf3-gdf9 physical interaction relationship: participates_in CCO:I0008255 ! kif22-gdf9 physical interaction relationship: participates_in CCO:I0008274 ! mphosph6-gdf9 physical interaction relationship: participates_in CCO:I0008382 ! dleu1-gdf9 physical interaction relationship: participates_in CCO:I0008419 ! pmf1-gdf9 physical interaction relationship: participates_in CCO:I0016048 ! gadd45g-gdf9 physical interaction relationship: participates_in CCO:I0019601 ! lsm3-gdf9 physical interaction relationship: participates_in CCO:I0019602 ! rsrc1-gdf9 physical interaction relationship: participates_in CCO:I0019648 ! aof2-gdf9 physical interaction relationship: participates_in CCO:I0019675 ! trib3-gdf9 physical interaction relationship: participates_in CCO:I0019698 ! creld1-gdf9 physical interaction relationship: participates_in CCO:I0019800 ! prkra-gdf9 physical interaction relationship: participates_in CCO:I0019928 ! btbd2-gdf9 physical interaction relationship: participates_in CCO:I0019932 ! c7orf19-gdf9 physical interaction relationship: participates_in CCO:I0020007 ! fxyd6-gdf9 physical interaction relationship: participates_in CCO:I0020078 ! mycbp-gdf9 physical interaction relationship: participates_in CCO:I0020094 ! pafah1b3-gdf9 physical interaction relationship: participates_in CCO:I0020096 ! pcdha4-gdf9 physical interaction relationship: participates_in CCO:I0020125 ! prei3-gdf9 physical interaction relationship: participates_in CCO:I0020129 ! psmd11-gdf9 physical interaction relationship: participates_in CCO:I0020141 ! rab27a-gdf9 physical interaction relationship: participates_in CCO:I0020161 ! s100a8-gdf9 physical interaction relationship: participates_in CCO:I0020164 ! sat-gdf9 physical interaction relationship: participates_in CCO:I0020167 ! serpinb9-gdf9 physical interaction relationship: participates_in CCO:I0020170 ! smn1-gdf9 physical interaction relationship: participates_in CCO:I0020172 ! snrpg-gdf9 physical interaction relationship: participates_in CCO:I0020188 ! tdgf1-gdf9 physical interaction relationship: participates_in CCO:I0020196 ! tk1-gdf9 physical interaction relationship: participates_in CCO:I0020382 ! ndufb9-gdf9 physical interaction relationship: participates_in CCO:I0020464 ! strn4-gdf9 physical interaction relationship: participates_in CCO:I0020502 ! adpgk-gdf9 physical interaction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0006181 name: COX6C_HUMAN def: "Cytochrome c oxidase polypeptide VIc precursor" [UniProtKB:P09669] xref: EMBL:AAC73061.1 xref: EMBL:AAH00187.1 xref: EMBL:AAP35653.1 xref: EMBL:CAA31624.1 xref: UniProtKB:P09669 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004387 ! COX6C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008216 ! cox6c-ptn physical interaction relationship: transforms_into CCO:B0011337 ! COX6C_HUMAN-N6-acetyllysine60 [Term] id: CCO:B0006182 name: CRADD_HUMAN def: "Death domain-containing protein CRADD" [UniProtKB:P78560] synonym: "Caspase and RIP adapter with death domain" EXACT [UniProtKB:P78560] synonym: "RIP-associated protein with a death domain" EXACT [UniProtKB:P78560] xref: EMBL:AAB42217.1 xref: EMBL:AAC50952.1 xref: EMBL:AAH17042.1 xref: UniProtKB:P78560 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004393 ! CRADD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0008217 ! cradd-rif1 physical interaction relationship: participates_in CCO:I0016258 ! casp2-cradd-4 physical interaction relationship: participates_in CCO:I0017776 ! casp2-raidd-pidd physical interaction relationship: participates_in CCO:I0017777 ! casp2-raidd-pidd-1 physical interaction relationship: participates_in CCO:I0017778 ! casp2-raidd-pidd-2 physical interaction relationship: participates_in CCO:I0018021 ! casp2-cradd-1 physical interaction relationship: participates_in CCO:I0018022 ! lrdd-cradd-1 physical interaction relationship: participates_in CCO:I0018023 ! casp2-cradd-3 physical interaction relationship: participates_in CCO:I0018024 ! casp2-cradd-5 physical interaction relationship: participates_in CCO:I0018106 ! raidd-pidd-4 colocalization relationship: participates_in CCO:I0018617 ! casp2-cradd-6 physical interaction relationship: participates_in CCO:I0019957 ! cradd-c14orf1 physical interaction relationship: participates_in CCO:I0019958 ! cradd-eef1a1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0006183 name: DDX24_HUMAN def: "ATP-dependent RNA helicase DDX24" [UniProtKB:Q9GZR7] synonym: "DEAD box protein 24" EXACT [UniProtKB:Q9GZR7] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9GZR7] xref: EMBL:AAG02169.1 xref: EMBL:AAH08847.1 xref: EMBL:AAH09406.1 xref: EMBL:BAB15079.1 xref: EMBL:CAB66820.1 xref: UniProtKB:Q9GZR7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004457 ! DDX24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008218 ! ddx24-pin1 physical interaction relationship: participates_in CCO:I0019704 ! ddx24-git1 physical interaction relationship: participates_in CCO:I0019705 ! ddx24-pola2 physical interaction relationship: participates_in CCO:I0019966 ! ddx24-eif4a2 physical interaction relationship: participates_in CCO:I0019967 ! ddx24-sptan1 physical interaction relationship: participates_in CCO:I0020285 ! ddx24-dnmt2 physical interaction relationship: participates_in CCO:I0020286 ! ddx24-eif3s6 physical interaction relationship: participates_in CCO:I0020287 ! ddx24-hspcb physical interaction relationship: participates_in CCO:I0020288 ! ddx24-itgb3bp physical interaction relationship: participates_in CCO:I0020539 ! ddx24-c11orf15 physical interaction relationship: participates_in CCO:I0020540 ! ddx24-fadd physical interaction relationship: transforms_into CCO:B0011467 ! DDX24_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0011468 ! DDX24_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0011469 ! DDX24_HUMAN-Phosphoserine192 relationship: transforms_into CCO:B0011470 ! DDX24_HUMAN-Phosphothreonine302 relationship: transforms_into CCO:B0064709 ! DDX24_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0064710 ! DDX24_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0064711 ! DDX24_HUMAN-Phosphoserine295 [Term] id: CCO:B0006184 name: GLYC_HUMAN def: "Serine hydroxymethyltransferase, cytosolic" [UniProtKB:P34896] synonym: "EC 2.1.2.1" EXACT [UniProtKB:P34896] synonym: "Glycine hydroxymethyltransferase" EXACT [UniProtKB:P34896] synonym: "Serine methylase" EXACT [UniProtKB:P34896] synonym: "SHMT" EXACT [UniProtKB:P34896] xref: EMBL:AAA36018.1 xref: EMBL:AAA36019.1 xref: EMBL:AAA36020.1 xref: EMBL:AAA63257.1 xref: EMBL:AAH22874.1 xref: EMBL:AAH38598.1 xref: EMBL:CAB54838.1 xref: EMBL:CAB54839.1 xref: EMBL:CAB54840.1 xref: UniProtKB:P34896 xref: UniProtKB:Q9UMD1 xref: UniProtKB:Q9UMD2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004706 ! SHMT1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000791 ! glycine hydroxymethyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008221 ! dleu1-shmt1 physical interaction relationship: participates_in CCO:I0020169 ! shmt1-pim1 physical interaction relationship: transforms_into CCO:B0011947 ! GLYC_HUMAN-Phosphotyrosine34 [Term] id: CCO:B0006185 name: ODO2_HUMAN def: "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor" [UniProtKB:P36957] synonym: "Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex" EXACT [UniProtKB:P36957] synonym: "E2" EXACT [UniProtKB:P36957] synonym: "E2K" EXACT [UniProtKB:P36957] synonym: "EC 2.3.1.61" EXACT [UniProtKB:P36957] xref: EMBL:AAB59629.1 xref: EMBL:AAD30181.1 xref: EMBL:AAH00302.1 xref: EMBL:AAH01922.1 xref: EMBL:BAA03871.1 xref: EMBL:BAA05536.1 xref: EMBL:BAF82103.1 xref: EMBL:EAW81199.1 xref: UniProtKB:P36957 xref: UniProtKB:Q7LDY7 xref: UniProtKB:Q9BQ32 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005229 ! DLST_human relationship: has_function CCO:F0000620 ! dihydrolipoyllysine-residue succinyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004659 ! lipoic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0001915 ! oxoglutarate dehydrogenase complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008223 ! dlst-dlg5 physical interaction relationship: participates_in CCO:I0019582 ! dlst-zhx1 physical interaction relationship: participates_in CCO:I0019779 ! pak4-dlst physical interaction relationship: participates_in CCO:I0019970 ! dlst-pfn2 physical interaction relationship: participates_in CCO:I0020002 ! flii-dlst physical interaction relationship: participates_in CCO:I0020081 ! nap1l1-dlst physical interaction [Term] id: CCO:B0006186 name: DUS12_HUMAN def: "Dual specificity protein phosphatase 12" [UniProtKB:Q9UNI6] synonym: "Dual specificity tyrosine phosphatase YVH1" EXACT [UniProtKB:Q9UNI6] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9UNI6] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9UNI6] xref: EMBL:AAD51134.1 xref: EMBL:AAH06286.1 xref: EMBL:AAP35279.1 xref: EMBL:CAH74153.1 xref: UniProtKB:Q5VXA8 xref: UniProtKB:Q9UNI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004519 ! DUSP12_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008224 ! dusp12-ptn physical interaction [Term] id: CCO:B0006187 name: SH3G3_HUMAN def: "Endophilin-A3" [UniProtKB:Q99963] synonym: "EEN-B2" EXACT [UniProtKB:Q99963] synonym: "Endophilin-3" EXACT [UniProtKB:Q99963] synonym: "SH3 domain protein 2C" EXACT [UniProtKB:Q99963] synonym: "SH3 domain-containing GRB2-like protein 3" EXACT [UniProtKB:Q99963] xref: EMBL:AAC04765.1 xref: EMBL:AAC04766.1 xref: EMBL:AAC04767.1 xref: EMBL:AAC04768.1 xref: EMBL:CAA67978.1 xref: UniProtKB:O43553 xref: UniProtKB:O43554 xref: UniProtKB:Q99963 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005609 ! SH3GL3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:I0008225 ! egfl6-sh3gl3 physical interaction relationship: participates_in CCO:I0008439 ! terf1-sh3gl3 physical interaction relationship: participates_in CCO:I0016059 ! hd-sh3gl3 physical interaction relationship: participates_in CCO:I0016060 ! hd-sh3gl3-1 physical interaction relationship: participates_in CCO:I0016061 ! hd-sh3gl3-2 physical interaction relationship: participates_in CCO:I0016096 ! vim-sh3gl3 physical interaction relationship: participates_in CCO:I0016097 ! ok/sw_cl_16-sh3gl3 physical interaction relationship: participates_in CCO:I0017749 ! atx2-cnsa3 physical interaction relationship: participates_in CCO:I0017751 ! atx2-cnsa3-2 physical interaction relationship: participates_in CCO:I0017753 ! cnsa1-cnsa3-1 physical interaction relationship: participates_in CCO:I0017754 ! cnsa3-cnsa2-1 physical interaction relationship: participates_in CCO:I0017755 ! cnsa3-cnsa3-1 physical interaction relationship: participates_in CCO:I0018508 ! atx2-cnsa3-1 physical interaction relationship: participates_in CCO:I0018513 ! cnsa1-cnsa3 physical interaction relationship: participates_in CCO:I0018516 ! cnsa3-cnsa3 physical interaction relationship: participates_in CCO:I0018517 ! cnsa2-cnsa3-1 physical interaction relationship: participates_in CCO:I0018519 ! cnsa3-cnsa1-1 physical interaction relationship: participates_in CCO:I0018520 ! cnsa3-cnsa2 physical interaction relationship: participates_in CCO:I0018521 ! cnas3-atx2 physical interaction relationship: participates_in CCO:I0018670 ! atx2-cnsa3-3 physical interaction relationship: participates_in CCO:I0019115 ! atxn2-sh3gl3 physical interaction relationship: participates_in CCO:I0019122 ! atxn2-sh3gl3-1 physical interaction relationship: participates_in CCO:I0019834 ! sh3gl1-sh3gl3 physical interaction relationship: participates_in CCO:I0019841 ! snrpn-sh3gl3 physical interaction relationship: participates_in CCO:I0019963 ! crip1-sh3gl3 physical interaction relationship: participates_in CCO:I0019969 ! c4orf17-sh3gl3 physical interaction relationship: participates_in CCO:I0019981 ! dppa4-sh3gl3 physical interaction relationship: participates_in CCO:I0019987 ! emd-sh3gl3 physical interaction relationship: participates_in CCO:I0020014 ! gpr51-sh3gl3 physical interaction relationship: participates_in CCO:I0020069 ! c16orf24-sh3gl3 physical interaction relationship: participates_in CCO:I0020085 ! ndufb9-sh3gl3 physical interaction relationship: participates_in CCO:I0020136 ! qtrt1-sh3gl3 physical interaction relationship: participates_in CCO:I0020147 ! rer1-sh3gl3 physical interaction relationship: participates_in CCO:I0020152 ! rpl35a-sh3gl3 physical interaction relationship: participates_in CCO:I0020214 ! wdr33-sh3gl3 physical interaction relationship: participates_in CCO:I0020224 ! aes-sh3gl3 physical interaction relationship: participates_in CCO:I0020236 ! arhgdia-sh3gl3 physical interaction relationship: participates_in CCO:I0020296 ! dpysl4-sh3gl3 physical interaction relationship: participates_in CCO:I0020342 ! igsf2-sh3gl3 physical interaction relationship: participates_in CCO:I0020355 ! krt9-sh3gl3 physical interaction relationship: participates_in CCO:I0020391 ! bles03-sh3gl3 physical interaction relationship: participates_in CCO:I0020669 ! snx24-sh3gl3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006188 name: SH3G2_HUMAN def: "Endophilin-A1" [UniProtKB:Q99962] synonym: "EEN-B1" EXACT [UniProtKB:Q99962] synonym: "Endophilin-1" EXACT [UniProtKB:Q99962] synonym: "SH3 domain protein 2A" EXACT [UniProtKB:Q99962] synonym: "SH3 domain-containing GRB2-like protein 2" EXACT [UniProtKB:Q99962] xref: EMBL:AAC04764.1 xref: EMBL:AAV38488.1 xref: EMBL:CAA67971.1 xref: EMBL:CAB92765.2 xref: EMBL:CAG46883.1 xref: EMBL:CAG46899.1 xref: EMBL:CAH70742.1 xref: UniProtKB:Q99962 xref: UniProtKB:Q9NQK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005608 ! SH3GL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008230 ! erh-sh3gl2 physical interaction relationship: participates_in CCO:I0008385 ! egfl6-sh3gl2 physical interaction relationship: participates_in CCO:I0017750 ! atx2-cnsa1-1 physical interaction relationship: participates_in CCO:I0017752 ! cnsa1-cnsa1-1 physical interaction relationship: participates_in CCO:I0017753 ! cnsa1-cnsa3-1 physical interaction relationship: participates_in CCO:I0017754 ! cnsa3-cnsa2-1 physical interaction relationship: participates_in CCO:I0017896 ! adam9-sh3gl2-3 physical interaction relationship: participates_in CCO:I0018340 ! adam9-sh3gl2-1 physical interaction relationship: participates_in CCO:I0018509 ! atx2-cnsa1 physical interaction relationship: participates_in CCO:I0018512 ! cnsa1-cnsa2 physical interaction relationship: participates_in CCO:I0018513 ! cnsa1-cnsa3 physical interaction relationship: participates_in CCO:I0018514 ! cnsa1-cnsa1 physical interaction relationship: participates_in CCO:I0018515 ! cnsa2-cnsa2 physical interaction relationship: participates_in CCO:I0018517 ! cnsa2-cnsa3-1 physical interaction relationship: participates_in CCO:I0018518 ! cnsa2-cnsa1 physical interaction relationship: participates_in CCO:I0018520 ! cnsa3-cnsa2 physical interaction relationship: participates_in CCO:I0018572 ! adam15-sh3gl2-1 physical interaction relationship: participates_in CCO:I0018669 ! atx2-cnsa1-2 physical interaction relationship: participates_in CCO:I0019121 ! atxn2-sh3gl2 physical interaction relationship: participates_in CCO:I0019404 ! emd-sh3gl2-1 physical interaction relationship: participates_in CCO:I0019438 ! adam15-sh3gl2-3 physical interaction relationship: participates_in CCO:I0019643 ! actg1-sh3gl2 physical interaction relationship: participates_in CCO:I0019986 ! emd-sh3gl2 physical interaction relationship: participates_in CCO:I0020023 ! hla_dqa1-sh3gl2 physical interaction relationship: participates_in CCO:I0020344 ! il6-sh3gl2 physical interaction relationship: participates_in CCO:I0020473 ! tcea2-sh3gl2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0014054 ! SH3G2_HUMAN-Phosphoserine75 [Term] id: CCO:B0006189 name: ETHE1_HUMAN def: "Protein ETHE1, mitochondrial precursor" [UniProtKB:O95571] synonym: "EC 3.-.-.-" EXACT [UniProtKB:O95571] synonym: "Ethylmalonic encephalopathy protein 1" EXACT [UniProtKB:O95571] synonym: "Hepatoma subtracted clone one protein" EXACT [UniProtKB:O95571] xref: EMBL:AAG09063.1 xref: EMBL:AAH08250.1 xref: EMBL:BAA34595.2 xref: UniProtKB:O95571 xref: UniProtKB:Q96HR0 xref: UniProtKB:Q9H001 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004591 ! ETHE1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0008231 ! ethe1-rif1 physical interaction [Term] id: CCO:B0006191 name: CCD99_HUMAN def: "Coiled-coil domain-containing protein 99" [UniProtKB:Q96EA4] synonym: "Arsenite-related gene 1 protein" EXACT [UniProtKB:Q96EA4] synonym: "Rrhabdomyosarcoma antigen protein MU-RMS-40.4A" EXACT [UniProtKB:Q96EA4] xref: EMBL:AAG01408.1 xref: EMBL:AAH12568.1 xref: EMBL:AAT44530.1 xref: EMBL:BAA91119.1 xref: EMBL:BAB85022.1 xref: UniProtKB:Q8TEC8 xref: UniProtKB:Q96EA4 xref: UniProtKB:Q9HD44 xref: UniProtKB:Q9NX97 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004239 ! CCDC99_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008234 ! flj20364-gps2 physical interaction relationship: transforms_into CCO:B0010983 ! CCD99_HUMAN-Phosphotyrosine279 relationship: transforms_into CCO:B0010984 ! CCD99_HUMAN-Phosphothreonine487 relationship: transforms_into CCO:B0010985 ! CCD99_HUMAN-Phosphoserine515 relationship: transforms_into CCO:B0010986 ! CCD99_HUMAN-Phosphoserine555 [Term] id: CCO:B0006192 name: FRIL_HUMAN def: "Ferritin light chain" [UniProtKB:P02792] synonym: "Ferritin L subunit" EXACT [UniProtKB:P02792] xref: EMBL:AAA35831.1 xref: EMBL:AAA52439.1 xref: EMBL:AAA52440.1 xref: EMBL:AAH02991.2 xref: EMBL:AAH04245.1 xref: EMBL:AAH08439.1 xref: EMBL:AAH16346.1 xref: EMBL:AAH16354.1 xref: EMBL:AAH18990.1 xref: EMBL:AAH58820.1 xref: EMBL:AAH62708.1 xref: EMBL:CAA27382.1 xref: EMBL:CAA27383.1 xref: EMBL:CAA27384.1 xref: EMBL:CAE11873.1 xref: UniProtKB:P02792 xref: UniProtKB:Q7Z2W1 xref: UniProtKB:Q9BTZ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004658 ! FTL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008243 ! ftl-ptn physical interaction relationship: participates_in CCO:I0008475 ! ftl-gadd45a physical interaction relationship: participates_in CCO:I0015700 ! fth1-ftl physical interaction relationship: participates_in CCO:I0020005 ! ftl-fth1 physical interaction relationship: participates_in CCO:I0020320 ! ftl-map3k12 physical interaction relationship: participates_in CCO:I0020321 ! ftl-taf10 physical interaction relationship: transforms_into CCO:B0011895 ! FRIL_HUMAN-N-acetylserine2 [Term] id: CCO:B0006193 name: VTDB_HUMAN def: "Vitamin D-binding protein precursor" [UniProtKB:P02774] synonym: "DBP" EXACT [UniProtKB:P02774] synonym: "Gc-globulin" EXACT [UniProtKB:P02774] synonym: "Group-specific component" EXACT [UniProtKB:P02774] synonym: "VDB" EXACT [UniProtKB:P02774] xref: EMBL:AAA19662.2 xref: EMBL:AAA52173.1 xref: EMBL:AAA61704.1 xref: EMBL:AAB29423.1 xref: EMBL:AAD14249.1 xref: EMBL:AAD14250.1 xref: EMBL:CAA26938.1 xref: UniProtKB:P02774 xref: UniProtKB:Q16309 xref: UniProtKB:Q16310 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005909 ! GC_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001637 ! vitamin D binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008065 ! vitamin transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0008244 ! gc-rif1 physical interaction [Term] id: CCO:B0006194 name: BL1S1_HUMAN def: "Biogenesis of lysosome-related organelles complex 1 subunit 1" [UniProtKB:P78537] synonym: "BLOC-1 subunit 1" EXACT [UniProtKB:P78537] synonym: "GCN5-like protein 1" EXACT [UniProtKB:P78537] synonym: "Protein RT14" EXACT [UniProtKB:P78537] xref: EMBL:AAB37682.1 xref: EMBL:BAA10887.1 xref: UniProtKB:P78537 xref: UniProtKB:Q6NZ45 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004167 ! BLOC1S1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008245 ! bloc1s1-ptn physical interaction relationship: participates_in CCO:I0018438 ! pbx2-gcn5l1 physical interaction relationship: transforms_into CCO:B0065798 ! BL1S1_HUMAN-Phosphothreonine107 [Term] id: CCO:B0006195 name: GLYAT_HUMAN def: "Glycine N-acyltransferase" [UniProtKB:Q6IB77] synonym: "AAc" EXACT [UniProtKB:Q6IB77] synonym: "Acyl-CoA:glycine N-acyltransferase" EXACT [UniProtKB:Q6IB77] synonym: "Aralkyl acyl-CoA N-acyltransferase" EXACT [UniProtKB:Q6IB77] synonym: "Aralkyl acyl-CoA:amino acid N-acyltransferase" EXACT [UniProtKB:Q6IB77] synonym: "EC 2.3.1.13" EXACT [UniProtKB:Q6IB77] synonym: "HRP-1(CLP)" EXACT [UniProtKB:Q6IB77] xref: EMBL:AAB81453.1 xref: EMBL:AAH09785.1 xref: EMBL:CAG33208.1 xref: UniProtKB:O14833 xref: UniProtKB:Q6IB77 xref: UniProtKB:Q96QK7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004705 ! GLYAT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008246 ! glyat-ptn physical interaction relationship: transforms_into CCO:B0011946 ! GLYAT_HUMAN-N6-acetyllysine20 [Term] id: CCO:B0006196 name: GBRAP_HUMAN def: "Gamma-aminobutyric acid receptor-associated protein" [UniProtKB:O95166] synonym: "GABA(A) receptor-associated protein" EXACT [UniProtKB:O95166] synonym: "MM46" EXACT [UniProtKB:O95166] xref: EMBL:AAD02337.1 xref: EMBL:AAD32455.1 xref: EMBL:AAD47641.1 xref: EMBL:AAG09694.1 xref: EMBL:BAB21549.1 xref: UniProtKB:O95166 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004689 ! GABARAP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_function CCO:F0008016 ! GABA receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000083 ! autophagic vacuole membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000371 ! smooth endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008248 ! hdac5-gabarap physical interaction relationship: participates_in CCO:I0017408 ! atg7-gabarap direct interaction relationship: participates_in CCO:I0020504 ! aes-gabarap physical interaction relationship: participates_in CCO:I0020542 ! dmpk-gabarap physical interaction [Term] id: CCO:B0006197 name: HSPB3_HUMAN def: "Heat shock protein beta-3" [UniProtKB:Q12988] synonym: "Heat shock 17 kDa protein" EXACT [UniProtKB:Q12988] synonym: "HspB3" EXACT [UniProtKB:Q12988] xref: EMBL:AAD05360.1 xref: EMBL:CAA76848.1 xref: UniProtKB:Q12988 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004840 ! HSPB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008249 ! hspb3-rif1 physical interaction relationship: participates_in CCO:I0020033 ! hspb3-setdb1 physical interaction relationship: participates_in CCO:I0020332 ! hspb3-anp32a physical interaction relationship: participates_in CCO:I0020333 ! hspb3-med31 physical interaction relationship: participates_in CCO:I0020334 ! hspb3-med8 physical interaction relationship: participates_in CCO:I0020335 ! hspb3-ramp3 physical interaction [Term] id: CCO:B0006198 name: CENPR_HUMAN def: "Centromere protein R" [UniProtKB:Q13352] synonym: "Beta3-endonexin" EXACT [UniProtKB:Q13352] synonym: "CENP-R" EXACT [UniProtKB:Q13352] synonym: "Integrin beta-3-binding protein" EXACT [UniProtKB:Q13352] synonym: "Nuclear receptor-interacting factor 3" EXACT [UniProtKB:Q13352] xref: EMBL:AAC50294.1 xref: EMBL:AAC50295.1 xref: EMBL:AAF00239.1 xref: EMBL:AAH09929.1 xref: EMBL:AAH14385.1 xref: EMBL:CAI15771.1 xref: EMBL:CAI15772.1 xref: EMBL:CAI18958.1 xref: EMBL:CAI18959.1 xref: UniProtKB:Q13352 xref: UniProtKB:Q13353 xref: UniProtKB:Q5RJ42 xref: UniProtKB:Q5RJ44 xref: UniProtKB:Q5RJ45 xref: UniProtKB:Q7KYX2 xref: UniProtKB:Q96CD5 xref: UniProtKB:Q9UKB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004328 ! ITGB3BP_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0008252 ! itgb3bp-rif1 physical interaction relationship: participates_in CCO:I0008794 ! itgb3bp-psme1 physical interaction relationship: participates_in CCO:I0015632 ! col4a3bp-itgb3bp physical interaction relationship: participates_in CCO:I0015761 ! arfip2-itgb3bp physical interaction relationship: participates_in CCO:I0019596 ! itgb3bp-aldh2 physical interaction relationship: participates_in CCO:I0019597 ! itgb3bp-kiaa1377 physical interaction relationship: participates_in CCO:I0019746 ! itgb3bp-actg1 physical interaction relationship: participates_in CCO:I0019747 ! itgb3bp-flj10094 physical interaction relationship: participates_in CCO:I0019748 ! itgb3bp-git1 physical interaction relationship: participates_in CCO:I0019749 ! itgb3bp-hip1 physical interaction relationship: participates_in CCO:I0019750 ! itgb3bp-pola2 physical interaction relationship: participates_in CCO:I0020041 ! itgb3bp-centb5 physical interaction relationship: participates_in CCO:I0020042 ! itgb3bp-creld1 physical interaction relationship: participates_in CCO:I0020043 ! itgb3bp-fundc2 physical interaction relationship: participates_in CCO:I0020044 ! itgb3bp-pdha1 physical interaction relationship: participates_in CCO:I0020045 ! itgb3bp-rpl6 physical interaction relationship: participates_in CCO:I0020046 ! itgb3bp-upf3b physical interaction relationship: participates_in CCO:I0020288 ! ddx24-itgb3bp physical interaction relationship: participates_in CCO:I0020345 ! itgb3bp-abcf1 physical interaction relationship: participates_in CCO:I0020346 ! itgb3bp-akt1s1 physical interaction relationship: participates_in CCO:I0020347 ! itgb3bp-flj20534 physical interaction relationship: participates_in CCO:I0020348 ! itgb3bp-mrps31 physical interaction relationship: participates_in CCO:I0020349 ! itgb3bp-ofd1 physical interaction relationship: participates_in CCO:I0020350 ! itgb3bp-usp33 physical interaction relationship: participates_in CCO:I0020351 ! itgb3bp-wfs1 physical interaction relationship: participates_in CCO:I0020433 ! recql5-itgb3bp physical interaction relationship: participates_in CCO:I0020578 ! itgb3bp-os_9 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0011177 ! CENPR_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0064287 ! CENPR_HUMAN-Phosphoserine17 [Term] id: CCO:B0006199 name: ITSN2_HUMAN def: "Intersectin-2" [UniProtKB:Q9NZM3] synonym: "SH3 domain-containing protein 1B" EXACT [UniProtKB:Q9NZM3] synonym: "SH3P18" EXACT [UniProtKB:Q9NZM3] synonym: "SH3P18-like WASP-associated protein" EXACT [UniProtKB:Q9NZM3] xref: EMBL:AAC50593.1 xref: EMBL:AAD00899.1 xref: EMBL:AAF59903.1 xref: EMBL:AAF59904.1 xref: EMBL:AAF63600.1 xref: EMBL:BAA86570.1 xref: EMBL:BAA91068.1 xref: EMBL:BAB13841.1 xref: UniProtKB:O95062 xref: UniProtKB:Q15812 xref: UniProtKB:Q9HAK4 xref: UniProtKB:Q9NXE6 xref: UniProtKB:Q9NYG0 xref: UniProtKB:Q9NZM2 xref: UniProtKB:Q9NZM3 xref: UniProtKB:Q9ULG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004906 ! ITSN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008253 ! itsn2-ptn physical interaction relationship: participates_in CCO:I0017281 ! synj2-itsn2 physical interaction relationship: participates_in CCO:I0017301 ! sema6a-itsn2 physical interaction relationship: participates_in CCO:I0017302 ! kiaa1549-itsn2 physical interaction relationship: participates_in CCO:I0017329 ! lsm8-itsn2 physical interaction relationship: participates_in CCO:I0020049 ! itsn2-tbl3 physical interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0012429 ! ITSN2_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0012430 ! ITSN2_HUMAN-Phosphotyrosine552 relationship: transforms_into CCO:B0012431 ! ITSN2_HUMAN-Phosphotyrosine858 relationship: transforms_into CCO:B0012432 ! ITSN2_HUMAN-Phosphotyrosine967 relationship: transforms_into CCO:B0067176 ! ITSN2_HUMAN-Phosphoserine883 relationship: transforms_into CCO:B0067177 ! ITSN2_HUMAN-Phosphoserine888 [Term] id: CCO:B0006200 name: WWC1_HUMAN def: "Protein WWC1" [UniProtKB:Q8IX03] synonym: "HBeAg-binding protein 3" EXACT [UniProtKB:Q8IX03] synonym: "KIBRA" EXACT [UniProtKB:Q8IX03] synonym: "Kidney and brain protein" EXACT [UniProtKB:Q8IX03] synonym: "WW domain-containing protein 1" EXACT [UniProtKB:Q8IX03] xref: EMBL:AAH04394.1 xref: EMBL:AAH17746.1 xref: EMBL:AAO15881.1 xref: EMBL:AAO73817.1 xref: EMBL:AAQ09942.1 xref: EMBL:BAA74892.1 xref: EMBL:CAE45903.1 xref: UniProtKB:O94946 xref: UniProtKB:Q6MZX4 xref: UniProtKB:Q6Y2F8 xref: UniProtKB:Q7Z4G8 xref: UniProtKB:Q8IX03 xref: UniProtKB:Q8WVM4 xref: UniProtKB:Q9BT29 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005935 ! WWC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008254 ! kibra-rif1 physical interaction relationship: participates_in CCO:I0017437 ! tnik-kibra physical interaction relationship: participates_in CCO:I0020621 ! pdcd8-kibra physical interaction relationship: transforms_into CCO:B0014699 ! WWC1_HUMAN-Phosphoserine899 relationship: transforms_into CCO:B0014700 ! WWC1_HUMAN-Phosphoserine922 relationship: transforms_into CCO:B0014701 ! WWC1_HUMAN-Phosphothreonine923 relationship: transforms_into CCO:B0014702 ! WWC1_HUMAN-Phosphoserine927 relationship: transforms_into CCO:B0071879 ! WWC1_HUMAN-Phosphothreonine912 relationship: transforms_into CCO:B0071880 ! WWC1_HUMAN-Phosphothreonine929 relationship: transforms_into CCO:B0071881 ! WWC1_HUMAN-Phosphoserine931 [Term] id: CCO:B0006201 name: IMMT_HUMAN def: "Mitochondrial inner membrane protein" [UniProtKB:Q16891] synonym: "Cell proliferation-inducing gene 4 protein" EXACT [UniProtKB:Q16891] synonym: "Mitofilin" EXACT [UniProtKB:Q16891] synonym: "p87/89" EXACT [UniProtKB:Q16891] xref: EMBL:AAA85336.1 xref: EMBL:AAF73126.1 xref: EMBL:AAH02412.1 xref: EMBL:AAH27458.1 xref: EMBL:AAP69987.1 xref: EMBL:BAA04653.1 xref: EMBL:BAA04654.1 xref: EMBL:BAA04655.1 xref: EMBL:BAA04656.1 xref: EMBL:CAD97612.1 xref: EMBL:CAG33074.1 xref: EMBL:CAH18389.1 xref: UniProtKB:Q14539 xref: UniProtKB:Q15092 xref: UniProtKB:Q16891 xref: UniProtKB:Q68D41 xref: UniProtKB:Q69HW5 xref: UniProtKB:Q6IBL0 xref: UniProtKB:Q7Z3X1 xref: UniProtKB:Q8TAJ5 xref: UniProtKB:Q9P0V2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004890 ! IMMT_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008256 ! kif22-immt physical interaction relationship: participates_in CCO:I0008287 ! pfdn1-immt physical interaction relationship: participates_in CCO:I0016054 ! immt-pias4 physical interaction relationship: participates_in CCO:I0019402 ! aof2-immt-1 physical interaction relationship: participates_in CCO:I0019695 ! chd3-immt physical interaction relationship: participates_in CCO:I0019906 ! ascc2-immt physical interaction relationship: participates_in CCO:I0020226 ! aof2-immt physical interaction relationship: participates_in CCO:I0020460 ! stmn4-immt physical interaction relationship: transforms_into CCO:B0012380 ! IMMT_HUMAN-N6-acetyllysine506 [Term] id: CCO:B0006202 name: PJA1_HUMAN def: "E3 ubiquitin-protein ligase Praja1" [UniProtKB:Q8NG27] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8NG27] synonym: "Praja-1" EXACT [UniProtKB:Q8NG27] synonym: "RING finger protein 70" EXACT [UniProtKB:Q8NG27] xref: EMBL:AAH48323.1 xref: EMBL:AAH75803.1 xref: EMBL:AAI05052.1 xref: EMBL:AAI05054.1 xref: EMBL:AAM53039.1 xref: EMBL:AAM53040.1 xref: EMBL:BAB13928.1 xref: EMBL:CAI41604.1 xref: UniProtKB:Q5JUT9 xref: UniProtKB:Q8NG27 xref: UniProtKB:Q8NG28 xref: UniProtKB:Q9HAC1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005320 ! PJA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008257 ! kif22-pja1 physical interaction relationship: participates_in CCO:I0019909 ! ascc2-pja1 physical interaction relationship: participates_in CCO:I0020626 ! pja1-znf440 physical interaction [Term] id: CCO:B0006203 name: TM1L1_HUMAN def: "TOM1-like protein 1" [UniProtKB:O75674] synonym: "Src-activating and signaling molecule protein" EXACT [UniProtKB:O75674] synonym: "Target of Myb-like protein 1" EXACT [UniProtKB:O75674] xref: EMBL:BAD96845.1 xref: EMBL:BAG37522.1 xref: EMBL:CAA08993.1 xref: EMBL:EAW94553.1 xref: UniProtKB:O75674 xref: UniProtKB:Q53G06 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005795 ! TOM1L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008258 ! kntc2-tom1l1 physical interaction relationship: participates_in CCO:I0019703 ! cugbp1-tom1l1 physical interaction relationship: participates_in CCO:I0020015 ! gsn-tom1l1 physical interaction relationship: participates_in CCO:I0020416 ! pwp2h-tom1l1 physical interaction relationship: participates_in CCO:I0020638 ! rab18-tom1l1 physical interaction relationship: transforms_into CCO:B0014415 ! TM1L1_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0014417 ! TM1L1_HUMAN-Phosphotyrosine460 [Term] id: CCO:B0006204 name: MAGD1_HUMAN def: "Melanoma-associated antigen D1" [UniProtKB:Q9Y5V3] synonym: "MAGE tumor antigen CCF" EXACT [UniProtKB:Q9Y5V3] synonym: "MAGE-D1 antigen" EXACT [UniProtKB:Q9Y5V3] synonym: "Neurotrophin receptor-interacting MAGE homolog" EXACT [UniProtKB:Q9Y5V3] xref: EMBL:AAD31421.1 xref: EMBL:AAG09704.1 xref: EMBL:AAG23757.1 xref: EMBL:AAG35551.1 xref: EMBL:AAH14070.1 xref: EMBL:AAH32473.1 xref: EMBL:AAQ14483.1 xref: EMBL:CAB63752.1 xref: EMBL:CAH71560.1 xref: EMBL:CAH71561.1 xref: UniProtKB:Q5VSH6 xref: UniProtKB:Q8IZ84 xref: UniProtKB:Q8WY92 xref: UniProtKB:Q9H352 xref: UniProtKB:Q9HBT4 xref: UniProtKB:Q9UF36 xref: UniProtKB:Q9Y5V3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005020 ! MAGED1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008263 ! maged1-plk1 physical interaction relationship: participates_in CCO:I0018907 ! a2bp1-maged1 physical interaction relationship: participates_in CCO:I0020060 ! maged1-eif3s1 physical interaction relationship: participates_in CCO:I0020061 ! maged1-gpr135 physical interaction relationship: participates_in CCO:I0020062 ! maged1-rfx1 physical interaction relationship: participates_in CCO:I0020063 ! maged1-sirt7 physical interaction relationship: participates_in CCO:I0020064 ! maged1-tuba1 physical interaction relationship: participates_in CCO:I0020362 ! maged1-brp44l physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: transforms_into CCO:B0067849 ! MAGD1_HUMAN-Phosphotyrosine92 [Term] id: CCO:B0006206 name: AF9_HUMAN def: "Protein AF-9" [UniProtKB:P42568] synonym: "ALL1 fused gene from chromosome 9 protein" EXACT [UniProtKB:P42568] synonym: "Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein" EXACT [UniProtKB:P42568] synonym: "YEATS domain-containing protein 3" EXACT [UniProtKB:P42568] xref: EMBL:AAA58361.1 xref: EMBL:CAH70705.1 xref: EMBL:CAI14771.1 xref: EMBL:EAW58631.1 xref: UniProtKB:B1AMQ2 xref: UniProtKB:P42568 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004035 ! MLLT3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008266 ! mllt3-ptn physical interaction relationship: participates_in CCO:I0008267 ! mllt3-rif1 physical interaction relationship: participates_in CCO:I0020073 ! mllt3-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020074 ! mllt3-eef1a1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065459 ! AF9_HUMAN-Phosphoserine288 relationship: transforms_into CCO:B0065460 ! AF9_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0065461 ! AF9_HUMAN-Phosphoserine412 relationship: transforms_into CCO:B0065462 ! AF9_HUMAN-Phosphoserine419 relationship: transforms_into CCO:B0065463 ! AF9_HUMAN-Phosphoserine429 relationship: transforms_into CCO:B0065464 ! AF9_HUMAN-Phosphoserine483 [Term] id: CCO:B0006207 name: MPP3_HUMAN def: "MAGUK p55 subfamily member 3" [UniProtKB:Q13368] synonym: "Discs large homolog 3" EXACT [UniProtKB:Q13368] synonym: "Protein MPP3" EXACT [UniProtKB:Q13368] xref: EMBL:AAB36964.1 xref: EMBL:AAH47017.1 xref: EMBL:AAH56865.1 xref: EMBL:CAJ18313.1 xref: EMBL:CAJ18315.1 xref: UniProtKB:Q13368 xref: UniProtKB:Q4GX05 xref: UniProtKB:Q6PGR3 xref: UniProtKB:Q86SV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005120 ! MPP3_human relationship: has_function CCO:F0000802 ! guanylate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0008275 ! mpp3-mcm2 physical interaction relationship: participates_in CCO:I0008410 ! mpp3-plk2 physical interaction relationship: participates_in CCO:I0020075 ! mpp3-hap1 physical interaction relationship: participates_in CCO:I0020370 ! mpp3-c4orf14 physical interaction relationship: participates_in CCO:I0020371 ! mpp3-gng7 physical interaction relationship: participates_in CCO:I0020372 ! mpp3-mdh1 physical interaction relationship: participates_in CCO:I0020373 ! mpp3-mgc16597 physical interaction relationship: participates_in CCO:I0020374 ! mpp3-rps2 physical interaction relationship: participates_in CCO:I0020594 ! mpp3-b3gntl1 physical interaction relationship: participates_in CCO:I0020595 ! mpp3-crabp1 physical interaction relationship: participates_in CCO:I0020596 ! mpp3-idua physical interaction relationship: participates_in CCO:I0020597 ! mpp3-insm1 physical interaction relationship: participates_in CCO:I0020598 ! mpp3-kbtbd4 physical interaction relationship: participates_in CCO:I0020599 ! mpp3-mopt physical interaction relationship: participates_in CCO:I0020600 ! mpp3-rab31 physical interaction relationship: participates_in CCO:I0020601 ! mpp3-sf3b3 physical interaction relationship: participates_in CCO:I0020602 ! mpp3-trim41 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006208 name: RT06_HUMAN def: "28S ribosomal protein S6, mitochondrial" [UniProtKB:P82932] synonym: "MRP-S6" EXACT [UniProtKB:P82932] synonym: "S6mt" EXACT [UniProtKB:P82932] xref: EMBL:AAH00547.2 xref: EMBL:AAH04976.2 xref: EMBL:AAH10076.1 xref: EMBL:AAH51302.1 xref: EMBL:AAL35739.1 xref: EMBL:BAB40995.1 xref: EMBL:BAB54937.1 xref: UniProtKB:P82932 xref: UniProtKB:Q96Q64 xref: UniProtKB:Q9BSK8 xref: UniProtKB:Q9BW89 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005544 ! MRPS6_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008276 ! mrps6-rif1 physical interaction [Term] id: CCO:B0006209 name: MYCBP_HUMAN def: "C-Myc-binding protein" [UniProtKB:Q99417] synonym: "AMY-1" EXACT [UniProtKB:Q99417] synonym: "Associate of Myc 1" EXACT [UniProtKB:Q99417] xref: EMBL:AAH08686.1 xref: EMBL:AAP35773.1 xref: EMBL:BAA09338.1 xref: EMBL:BAA22408.1 xref: EMBL:CAI23050.1 xref: UniProtKB:Q5TA64 xref: UniProtKB:Q96HE2 xref: UniProtKB:Q99417 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005141 ! MYCBP_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0008277 ! mycbp-ptn physical interaction relationship: participates_in CCO:I0020077 ! mycbp-cops6 physical interaction relationship: participates_in CCO:I0020078 ! mycbp-gdf9 physical interaction relationship: participates_in CCO:I0020377 ! mycbp-cfl1 physical interaction relationship: participates_in CCO:I0020378 ! mycbp-kiaa1337 physical interaction relationship: participates_in CCO:I0020379 ! mycbp-ssrp1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0006211 name: TF3C1_HUMAN def: "General transcription factor 3C polypeptide 1" [UniProtKB:Q12789] synonym: "TF3C-alpha" EXACT [UniProtKB:Q12789] synonym: "TFIIIC 220 kDa subunit" EXACT [UniProtKB:Q12789] synonym: "TFIIIC box B-binding subunit" EXACT [UniProtKB:Q12789] synonym: "TFIIIC220" EXACT [UniProtKB:Q12789] synonym: "Transcription factor IIIC subunit alpha" EXACT [UniProtKB:Q12789] xref: EMBL:AAA17985.1 xref: EMBL:AAA85638.1 xref: EMBL:AAB67637.1 xref: EMBL:AAC05811.1 xref: EMBL:AAH44857.1 xref: EMBL:AAI37230.1 xref: UniProtKB:B2RP21 xref: UniProtKB:Q12789 xref: UniProtKB:Q12838 xref: UniProtKB:Q6DKN9 xref: UniProtKB:Q9Y4W9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005764 ! GTF3C1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008328 ! supt5h-gtf3c1 physical interaction relationship: participates_in CCO:I0016812 ! nfkb2-a_951c1a1 physical interaction relationship: participates_in CCO:I0019763 ! mapk10-gtf3c1 physical interaction relationship: participates_in CCO:I0019904 ! ascc2-gtf3c1 physical interaction relationship: participates_in CCO:I0019951 ! klf6-gtf3c1 physical interaction relationship: participates_in CCO:I0019955 ! cpe-gtf3c1 physical interaction relationship: participates_in CCO:I0019998 ! fgfr3-gtf3c1 physical interaction relationship: participates_in CCO:I0020039 ! igfbp3-gtf3c1 physical interaction relationship: participates_in CCO:I0020184 ! tbc1d17-gtf3c1 physical interaction relationship: participates_in CCO:I0020275 ! chn1-gtf3c1 physical interaction relationship: transforms_into CCO:B0014337 ! TF3C1_HUMAN-Phosphoserine739 relationship: transforms_into CCO:B0014338 ! TF3C1_HUMAN-Phosphoserine751 relationship: transforms_into CCO:B0014339 ! TF3C1_HUMAN-Phosphoserine1062 relationship: transforms_into CCO:B0014340 ! TF3C1_HUMAN-Phosphoserine1068 relationship: transforms_into CCO:B0014341 ! TF3C1_HUMAN-Phosphoserine1653 relationship: transforms_into CCO:B0014342 ! TF3C1_HUMAN-Phosphoserine1865 relationship: transforms_into CCO:B0014343 ! TF3C1_HUMAN-Phosphoserine1868 relationship: transforms_into CCO:B0014344 ! TF3C1_HUMAN-Phosphoserine1969 relationship: transforms_into CCO:B0048409 ! TF3C1_HUMAN-Phosphoserine1856 relationship: transforms_into CCO:B0071365 ! TF3C1_HUMAN-Phosphothreonine774 relationship: transforms_into CCO:B0071366 ! TF3C1_HUMAN-Phosphothreonine1064 relationship: transforms_into CCO:B0071367 ! TF3C1_HUMAN-Phosphoserine1611 relationship: transforms_into CCO:B0071368 ! TF3C1_HUMAN-Phosphoserine1632 [Term] id: CCO:B0006212 name: PAEP_HUMAN def: "Glycodelin precursor" [UniProtKB:P09466] synonym: "GD" EXACT [UniProtKB:P09466] synonym: "PAEG" EXACT [UniProtKB:P09466] synonym: "PEG" EXACT [UniProtKB:P09466] synonym: "Placental protein 14" EXACT [UniProtKB:P09466] synonym: "PP14" EXACT [UniProtKB:P09466] synonym: "Pregnancy-associated endometrial alpha-2 globulin" EXACT [UniProtKB:P09466] synonym: "Progestagen-associated endometrial protein" EXACT [UniProtKB:P09466] synonym: "Progesterone-associated endometrial protein" EXACT [UniProtKB:P09466] xref: EMBL:AAA35801.1 xref: EMBL:AAA35802.1 xref: EMBL:AAA60147.1 xref: EMBL:AAA60148.1 xref: EMBL:AAH69451.1 xref: EMBL:AAH69562.1 xref: EMBL:AAI12305.1 xref: EMBL:AAI13729.1 xref: EMBL:CAB43305.1 xref: EMBL:CAI17197.1 xref: UniProtKB:P09466 xref: UniProtKB:Q5T6T1 xref: UniProtKB:Q9UG92 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005255 ! PAEP_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008284 ! paep-rif1 physical interaction relationship: participates_in CCO:I0008813 ! ube2e1-paep physical interaction relationship: participates_in CCO:I0008962 ! smad3-sry-3 physical interaction relationship: participates_in CCO:I0019773 ! paep-g22p1 physical interaction [Term] id: CCO:B0006214 name: HIP1_HUMAN def: "Huntingtin-interacting protein 1" [UniProtKB:O00291] synonym: "HIP-I" EXACT [UniProtKB:O00291] xref: EMBL:AAC33564.1 xref: EMBL:AAC51257.1 xref: EMBL:AAI10546.1 xref: EMBL:AAL87037.1 xref: EMBL:CAA70574.1 xref: UniProtKB:O00291 xref: UniProtKB:O00328 xref: UniProtKB:Q2TB58 xref: UniProtKB:Q8TDL4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004807 ! HIP1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008286 ! pfdn1-hip1 physical interaction relationship: participates_in CCO:I0016058 ! hd-hip1 physical interaction relationship: participates_in CCO:I0019749 ! itgb3bp-hip1 physical interaction [Term] id: CCO:B0006215 name: PSME1_HUMAN def: "Proteasome activator complex subunit 1" [UniProtKB:Q06323] synonym: "11S regulator complex subunit alpha" EXACT [UniProtKB:Q06323] synonym: "Activator of multicatalytic protease subunit 1" EXACT [UniProtKB:Q06323] synonym: "IGUP I-5111" EXACT [UniProtKB:Q06323] synonym: "Interferon gamma up-regulated I-5111 protein" EXACT [UniProtKB:Q06323] synonym: "PA28a" EXACT [UniProtKB:Q06323] synonym: "PA28alpha" EXACT [UniProtKB:Q06323] synonym: "Proteasome activator 28 subunit alpha" EXACT [UniProtKB:Q06323] synonym: "REG-alpha" EXACT [UniProtKB:Q06323] xref: EMBL:AAA16521.1 xref: EMBL:AAA53230.1 xref: EMBL:AAF02217.1 xref: EMBL:AAH00352.1 xref: EMBL:AAH07503.1 xref: EMBL:AAV38144.1 xref: EMBL:BAA28836.1 xref: UniProtKB:Q06323 xref: UniProtKB:Q9UEF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005393 ! PSME1_human relationship: has_function CCO:F0001986 ! proteasome activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000548 ! proteasome activator complex relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008288 ! pfdn1-psme1 physical interaction relationship: participates_in CCO:I0008698 ! psme1-psme2 physical interaction relationship: participates_in CCO:I0008794 ! itgb3bp-psme1 physical interaction relationship: participates_in CCO:I0008796 ! psme1-chd3 physical interaction relationship: participates_in CCO:I0008798 ! psme1-psme1 physical interaction relationship: participates_in CCO:I0008799 ! psme1-vcl physical interaction relationship: participates_in CCO:I0008800 ! psme1-vim physical interaction relationship: participates_in CCO:I0008816 ! usp22-psme1 physical interaction relationship: participates_in CCO:I0008819 ! c2f-psme1 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0006216 name: PKHA4_HUMAN def: "Pleckstrin homology domain-containing family A member 4" [UniProtKB:Q9H4M7] synonym: "PEPP-1" EXACT [UniProtKB:Q9H4M7] synonym: "Phosphoinositol 3-phosphate-binding protein 1" EXACT [UniProtKB:Q9H4M7] xref: EMBL:AAG01896.1 xref: EMBL:AAH24157.1 xref: EMBL:AAH33832.1 xref: EMBL:AAH64601.1 xref: UniProtKB:Q8N4M8 xref: UniProtKB:Q8N658 xref: UniProtKB:Q9H4M7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005325 ! PLEKHA4_human relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008290 ! plekha4-rif1 physical interaction relationship: participates_in CCO:I0020114 ! plekha4-htatip physical interaction relationship: participates_in CCO:I0020115 ! plekha4-setdb1 physical interaction [Term] id: CCO:B0006217 name: SCG1_HUMAN def: "Secretogranin-1 precursor" [UniProtKB:P05060] synonym: "CgB" EXACT [UniProtKB:P05060] synonym: "Chromogranin-B" EXACT [UniProtKB:P05060] synonym: "Secretogranin I" EXACT [UniProtKB:P05060] synonym: "SgI" EXACT [UniProtKB:P05060] xref: EMBL:AAH00375.1 xref: EMBL:BAD92949.1 xref: EMBL:BAF82075.1 xref: EMBL:CAA68271.1 xref: EMBL:CAB55272.1 xref: EMBL:CAC34360.1 xref: EMBL:CAG33007.1 xref: EMBL:EAX10410.1 xref: UniProtKB:A8K021 xref: UniProtKB:P05060 xref: UniProtKB:Q59EU9 xref: UniProtKB:Q6IBS6 xref: UniProtKB:Q9BQV6 xref: UniProtKB:Q9UC25 xref: UniProtKB:Q9UJA6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005572 ! CHGB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008295 ! pold1-chgb physical interaction relationship: participates_in CCO:I0008302 ! pten-chgb physical interaction relationship: participates_in CCO:I0019995 ! fgfr3-chgb physical interaction relationship: participates_in CCO:I0020448 ! safb2-chgb physical interaction relationship: participates_in CCO:I0020449 ! atxn2-chgb physical interaction relationship: participates_in CCO:I0020660 ! rxrg-chgb physical interaction relationship: participates_in CCO:I0020682 ! ubtf-chgb physical interaction relationship: transforms_into CCO:B0013968 ! SCG1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0013969 ! SCG1_HUMAN-N6-acetyllysine153 relationship: transforms_into CCO:B0013971 ! SCG1_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0013972 ! SCG1_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0013973 ! SCG1_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0013974 ! SCG1_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0013975 ! SCG1_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0013976 ! SCG1_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0013977 ! SCG1_HUMAN-Sulfotyrosine341 relationship: transforms_into CCO:B0013978 ! SCG1_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0013979 ! SCG1_HUMAN-Phosphoserine405 relationship: transforms_into CCO:B0013980 ! SCG1_HUMAN-Phosphoserine617 relationship: transforms_into CCO:B0013981 ! SCG1_HUMAN-Phosphoserine626 relationship: transforms_into CCO:B0041181 ! SCG1_HUMAN-Phosphothreonine79 relationship: transforms_into CCO:B0041182 ! SCG1_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0041183 ! SCG1_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0041184 ! SCG1_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0041185 ! SCG1_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0041186 ! SCG1_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0041187 ! SCG1_HUMAN-Sulfotyrosine471 relationship: transforms_into CCO:B0041188 ! SCG1_HUMAN-Sulfotyrosine474 relationship: transforms_into CCO:B0041189 ! SCG1_HUMAN-Phosphoserine533 relationship: transforms_into CCO:B0041190 ! SCG1_HUMAN-Phosphoserine534 relationship: transforms_into CCO:B0041191 ! SCG1_HUMAN-Sulfotyrosine566 relationship: transforms_into CCO:B0041192 ! SCG1_HUMAN-Sulfotyrosine568 relationship: transforms_into CCO:B0041193 ! SCG1_HUMAN-Phosphoserine631 [Term] id: CCO:B0006218 name: PQBP1_HUMAN def: "Polyglutamine-binding protein 1" [UniProtKB:O60828] synonym: "38 kDa nuclear protein containing a WW domain" EXACT [UniProtKB:O60828] synonym: "Npw38" EXACT [UniProtKB:O60828] synonym: "Polyglutamine tract-binding protein 1" EXACT [UniProtKB:O60828] synonym: "PQBP-1" EXACT [UniProtKB:O60828] xref: EMBL:AAH12358.1 xref: EMBL:BAA76400.1 xref: EMBL:BAB16702.1 xref: EMBL:BAB16703.1 xref: EMBL:BAB16704.1 xref: EMBL:BAB16705.1 xref: EMBL:BAB16706.1 xref: EMBL:BAB16707.1 xref: EMBL:BAB16708.1 xref: EMBL:BAB16709.1 xref: EMBL:CAA06750.1 xref: EMBL:CAB44309.1 xref: EMBL:CAJ00537.1 xref: EMBL:CAJ00538.1 xref: EMBL:CAJ00539.1 xref: EMBL:CAJ00540.1 xref: EMBL:CAJ00541.1 xref: EMBL:CAJ00542.1 xref: EMBL:CAJ00543.1 xref: EMBL:CAJ00544.1 xref: EMBL:CAJ00545.1 xref: EMBL:CAJ00546.1 xref: EMBL:CAJ00547.1 xref: EMBL:CAJ00548.1 xref: EMBL:CAJ00549.1 xref: EMBL:CAJ00550.1 xref: UniProtKB:O60828 xref: UniProtKB:Q4VY25 xref: UniProtKB:Q4VY26 xref: UniProtKB:Q4VY27 xref: UniProtKB:Q4VY29 xref: UniProtKB:Q4VY30 xref: UniProtKB:Q4VY34 xref: UniProtKB:Q4VY35 xref: UniProtKB:Q4VY36 xref: UniProtKB:Q4VY37 xref: UniProtKB:Q4VY38 xref: UniProtKB:Q9GZP2 xref: UniProtKB:Q9GZU4 xref: UniProtKB:Q9GZZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005371 ! PQBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008298 ! pqbp1-rif1 physical interaction relationship: participates_in CCO:I0017619 ! pqbp1-rcv1 physical interaction relationship: participates_in CCO:I0017620 ! pqbp1-wbp11 physical interaction relationship: participates_in CCO:I0019797 ! pqbp1-med31 physical interaction relationship: participates_in CCO:I0019798 ! pqbp1-eef1a1 physical interaction relationship: participates_in CCO:I0020410 ! pqbp1-c14orf1 physical interaction relationship: participates_in CCO:I0020631 ! pqbp1-cltb physical interaction relationship: participates_in CCO:I0020632 ! pqbp1-rab8a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0006219 name: PSB10_HUMAN def: "Proteasome subunit beta type-10 precursor" [UniProtKB:P40306] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P40306] synonym: "Macropain subunit MECl-1" EXACT [UniProtKB:P40306] synonym: "Multicatalytic endopeptidase complex subunit MECl-1" EXACT [UniProtKB:P40306] synonym: "Proteasome MECl-1" EXACT [UniProtKB:P40306] synonym: "Proteasome subunit beta-2i" EXACT [UniProtKB:P40306] xref: EMBL:AAH17198.1 xref: EMBL:AAH52369.1 xref: EMBL:AAV38528.1 xref: EMBL:AAV38529.1 xref: EMBL:CAA50709.1 xref: EMBL:CAA73982.1 xref: UniProtKB:P40306 xref: UniProtKB:Q5U098 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005387 ! PSMB10_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008300 ! psmb10-ptn physical interaction relationship: participates_in CCO:I0008727 ! alpha1-beta2i physical interaction relationship: participates_in CCO:I0008747 ! beta2i-beta3 physical interaction relationship: participates_in CCO:I0008748 ! beta3-beta2i physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0006220 name: ANGI_HUMAN def: "Angiogenin precursor" [UniProtKB:P03950] synonym: "EC 3.1.27.-" EXACT [UniProtKB:P03950] synonym: "Ribonuclease 5" EXACT [UniProtKB:P03950] synonym: "RNase 5" EXACT [UniProtKB:P03950] xref: EMBL:AAA51678.1 xref: EMBL:AAH54880.1 xref: EMBL:AAL67710.1 xref: EMBL:AAL67711.1 xref: EMBL:AAL67712.1 xref: EMBL:AAL67713.1 xref: EMBL:AAL67714.1 xref: UniProtKB:P03950 xref: UniProtKB:Q8WXE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004059 ! ANG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008301 ! pten-ang physical interaction relationship: participates_in CCO:I0017499 ! ang-actn2-1 physical interaction relationship: participates_in CCO:I0018189 ! ang-actn2-3 physical interaction relationship: participates_in CCO:I0018791 ! ang-actn2-2 physical interaction relationship: participates_in CCO:I0019918 ! atp6ap1-ang physical interaction relationship: participates_in CCO:I0020186 ! tdgf1-ang physical interaction relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002059 ! positive regulation of phosphorylation relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation relationship: transforms_into CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 [Term] id: CCO:B0006221 name: HBA_HUMAN def: "Hemoglobin subunit alpha" [UniProtKB:P69905] synonym: "Alpha-globin" EXACT [UniProtKB:P69905] synonym: "Hemoglobin alpha chain" EXACT [UniProtKB:P69905] xref: EMBL:AAB59407.1 xref: EMBL:AAB59408.1 xref: EMBL:AAC72839.1 xref: EMBL:AAC97373.1 xref: EMBL:AAF72612.1 xref: EMBL:AAH05931.1 xref: EMBL:AAH08572.1 xref: EMBL:AAH32122.1 xref: EMBL:AAH50661.1 xref: EMBL:AAI01847.1 xref: EMBL:AAI01849.1 xref: EMBL:AAK37554.1 xref: EMBL:AAK61215.1 xref: EMBL:AAK61216.1 xref: EMBL:AAM83102.1 xref: EMBL:AAN04486.1 xref: EMBL:ABD95910.1 xref: EMBL:ABD95911.1 xref: EMBL:ABF56144.1 xref: EMBL:CAA23748.1 xref: EMBL:CAA23750.1 xref: EMBL:CAA23752.1 xref: EMBL:CAA23774.1 xref: EMBL:CAB06554.1 xref: EMBL:CAB06555.1 xref: UniProtKB:P01922 xref: UniProtKB:P69905 xref: UniProtKB:Q3MIF5 xref: UniProtKB:Q96KF1 xref: UniProtKB:Q9NYR7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004779 ! HBA1_human relationship: encoded_by CCO:G0004780 ! HBA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008304 ! pten-hba1 physical interaction relationship: participates_in CCO:I0015857 ! hba1-hbb-9 direct interaction relationship: participates_in CCO:I0015859 ! hba1-hbb-13 direct interaction relationship: participates_in CCO:I0015860 ! hba1-hbb-14 direct interaction relationship: participates_in CCO:I0015861 ! hba1-hbb-15 direct interaction relationship: participates_in CCO:I0016198 ! hba1-hbb-16 direct interaction relationship: participates_in CCO:I0016199 ! hba1-hbb-17 direct interaction relationship: participates_in CCO:I0017790 ! hba1-hbb-12 direct interaction relationship: participates_in CCO:I0017950 ! hba1-hbb-10 direct interaction relationship: participates_in CCO:I0017951 ! hba1-hbb-11 direct interaction relationship: participates_in CCO:I0018257 ! hba1-hbb-18 direct interaction relationship: participates_in CCO:I0018710 ! hba1-hbb-8 direct interaction relationship: participates_in CCO:I0018732 ! hba1-hbb-1 direct interaction relationship: participates_in CCO:I0018733 ! hba1-hbb-2 direct interaction relationship: participates_in CCO:I0018734 ! hba1-hbb-3 direct interaction relationship: participates_in CCO:I0018735 ! hba1-hbb-4 direct interaction relationship: participates_in CCO:I0018736 ! hba1-hbb-5 direct interaction relationship: participates_in CCO:I0018737 ! hba1-hbb-6 direct interaction relationship: participates_in CCO:I0018738 ! hba1-hbb-7 direct interaction relationship: participates_in CCO:I0019184 ! ahsp-hba1-1 direct interaction relationship: participates_in CCO:I0020020 ! hba1-hbb physical interaction relationship: participates_in CCO:I0020606 ! nap1l1-hba1 physical interaction relationship: transforms_into CCO:B0066758 ! HBA_HUMAN-Phosphotyrosine25 relationship: transforms_into CCO:B0066759 ! HBA_HUMAN-Phosphotyrosine43 [Term] id: CCO:B0006222 name: RAB1A_HUMAN def: "Ras-related protein Rab-1A" [UniProtKB:P62820] synonym: "YPT1-related protein" EXACT [UniProtKB:P62820] xref: EMBL:AAA60240.1 xref: EMBL:AAH00905.1 xref: EMBL:AAM21077.1 xref: EMBL:BAB71048.1 xref: EMBL:CAB43369.1 xref: EMBL:CAE11872.1 xref: UniProtKB:P11476 xref: UniProtKB:P62820 xref: UniProtKB:Q96N61 xref: UniProtKB:Q9Y3T2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005409 ! RAB1A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:I0008305 ! rab1a-cdkn1a physical interaction relationship: participates_in CCO:I0008492 ! rab1a-mapre3 physical interaction relationship: participates_in CCO:I0008824 ! rab1a-psmd7 physical interaction relationship: participates_in CCO:I0015825 ! rab1a-rabac1 physical interaction relationship: participates_in CCO:I0020137 ! rab1a-rfk physical interaction relationship: participates_in CCO:I0020419 ! rab1a-q86tw2 physical interaction relationship: participates_in CCO:I0020420 ! rab1a-capns1 physical interaction relationship: participates_in CCO:I0020421 ! rab1a-creb1 physical interaction relationship: participates_in CCO:I0020422 ! rab1a-fscn1 physical interaction relationship: participates_in CCO:I0020423 ! rab1a-hivep1 physical interaction relationship: participates_in CCO:I0020424 ! rab1a-slc16a8 physical interaction relationship: participates_in CCO:I0020425 ! rab1a-tbc1d17 physical interaction relationship: participates_in CCO:I0020639 ! rab1a-syt5 physical interaction relationship: participates_in CCO:I0020640 ! rab1a-znf593 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0013655 ! RAB1A_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0013656 ! RAB1A_HUMAN-Phosphoserine194 [Term] id: CCO:B0006223 name: RB27A_HUMAN def: "Ras-related protein Rab-27A" [UniProtKB:P51159] synonym: "GTP-binding protein Ram" EXACT [UniProtKB:P51159] synonym: "Rab-27" EXACT [UniProtKB:P51159] xref: EMBL:AAC50271.2 xref: EMBL:AAC51195.1 xref: EMBL:AAD43049.1 xref: EMBL:AAD47629.1 xref: EMBL:AAI07681.1 xref: EMBL:AAL39097.1 xref: EMBL:AAM21101.1 xref: EMBL:CAG38735.1 xref: EMBL:CAG46494.1 xref: UniProtKB:O00195 xref: UniProtKB:P51159 xref: UniProtKB:Q6FI40 xref: UniProtKB:Q9UIR9 xref: UniProtKB:Q9Y5U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005437 ! RAB27A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008306 ! rab27a-rif1 physical interaction relationship: participates_in CCO:I0020138 ! rab27a-c14orf1 physical interaction relationship: participates_in CCO:I0020139 ! rab27a-cops6 physical interaction relationship: participates_in CCO:I0020140 ! rab27a-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020141 ! rab27a-gdf9 physical interaction relationship: participates_in CCO:I0020142 ! rab27a-kiaa1377 physical interaction relationship: participates_in CCO:I0020426 ! rab27a-eef1a1 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0013718 ! RB27A_HUMAN-Cysteine methyl ester221 [Term] id: CCO:B0006224 name: RECQ5_HUMAN def: "ATP-dependent DNA helicase Q5" [UniProtKB:O94762] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O94762] synonym: "RecQ protein-like 5" EXACT [UniProtKB:O94762] synonym: "RecQ5" EXACT [UniProtKB:O94762] xref: EMBL:AAD43061.1 xref: EMBL:AAD43062.1 xref: EMBL:AAH16911.1 xref: EMBL:BAA74454.1 xref: EMBL:BAA95952.1 xref: EMBL:BAA95953.1 xref: EMBL:BAA95954.1 xref: UniProtKB:O94762 xref: UniProtKB:Q9P1W7 xref: UniProtKB:Q9UNC8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005462 ! RECQL5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0008308 ! recql5-plk1 physical interaction relationship: participates_in CCO:I0008426 ! recql5-mtss1 physical interaction relationship: participates_in CCO:I0019854 ! timp1-recql5 physical interaction relationship: participates_in CCO:I0020145 ! recql5-creb1 physical interaction relationship: participates_in CCO:I0020280 ! cutl1-recql5 physical interaction relationship: participates_in CCO:I0020433 ! recql5-itgb3bp physical interaction relationship: participates_in CCO:I0020434 ! recql5-mapk8ip1 physical interaction relationship: participates_in CCO:I0020651 ! recql5-stambp physical interaction [Term] id: CCO:B0006225 name: ARFG1_HUMAN def: "ADP-ribosylation factor GTPase-activating protein 1" [UniProtKB:Q8N6T3] synonym: "ADP-ribosylation factor 1 GTPase-activating protein" EXACT [UniProtKB:Q8N6T3] synonym: "ARF1 GAP" EXACT [UniProtKB:Q8N6T3] synonym: "ARF1-directed GTPase-activating protein" EXACT [UniProtKB:Q8N6T3] synonym: "GAP protein" EXACT [UniProtKB:Q8N6T3] xref: EMBL:AAH00786.1 xref: EMBL:AAH06085.1 xref: EMBL:AAH11876.1 xref: EMBL:AAH28233.1 xref: EMBL:BAA88117.1 xref: EMBL:BAA91796.1 xref: EMBL:BAB55009.1 xref: EMBL:BAB55113.1 xref: EMBL:CAB70901.1 xref: UniProtKB:Q6PK71 xref: UniProtKB:Q8N6T3 xref: UniProtKB:Q96KC4 xref: UniProtKB:Q96T02 xref: UniProtKB:Q9NSU3 xref: UniProtKB:Q9NVF6 xref: UniProtKB:Q9UIL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004089 ! ARFGAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008309 ! rgs2-arfgap1 physical interaction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0010589 ! ARFG1_HUMAN-Phosphothreonine135 relationship: transforms_into CCO:B0010590 ! ARFG1_HUMAN-Phosphothreonine189 relationship: transforms_into CCO:B0010591 ! ARFG1_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0010592 ! ARFG1_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0010593 ! ARFG1_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0010594 ! ARFG1_HUMAN-Phosphoserine348 relationship: transforms_into CCO:B0010595 ! ARFG1_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0065699 ! ARFG1_HUMAN-Phosphoserine304 [Term] id: CCO:B0006226 name: DYL1_HUMAN def: "Dynein light chain 1, cytoplasmic" [UniProtKB:P63167] synonym: "8 kDa dynein light chain" EXACT [UniProtKB:P63167] synonym: "DLC8" EXACT [UniProtKB:P63167] synonym: "Dynein light chain LC8-type 1" EXACT [UniProtKB:P63167] synonym: "PIN" EXACT [UniProtKB:P63167] synonym: "Protein inhibitor of neuronal nitric oxide synthase" EXACT [UniProtKB:P63167] xref: EMBL:AAB04149.1 xref: EMBL:CAG28600.1 xref: UniProtKB:P63167 xref: UniProtKB:Q15701 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004527 ! DYNLL1_human relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000428 ! cytoplasmic dynein complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000995 ! dynein complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008310 ! rgs2-dncl1 physical interaction relationship: participates_in CCO:I0019583 ! dncl1-eef1a1 physical interaction relationship: participates_in CCO:I0019706 ! dncl1-c14orf1 physical interaction relationship: participates_in CCO:I0019707 ! dncl1-zhx1 physical interaction relationship: participates_in CCO:I0019971 ! dnajb9-dncl1 physical interaction relationship: participates_in CCO:I0020293 ! dncl1-dncl1 physical interaction relationship: participates_in CCO:I0020480 ! thap8-dncl1 physical interaction relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002058 ! negative regulation of phosphorylation [Term] id: CCO:B0006227 name: PRKN2_HUMAN def: "E3 ubiquitin-protein ligase parkin" [UniProtKB:O60260] synonym: "EC 6.3.2.-" EXACT [UniProtKB:O60260] synonym: "Parkinson disease protein 2" EXACT [UniProtKB:O60260] synonym: "Parkinson juvenile disease protein 2" EXACT [UniProtKB:O60260] xref: EMBL:AAH22014.1 xref: EMBL:AAM21457.1 xref: EMBL:AAM21458.1 xref: EMBL:AAM21461.1 xref: EMBL:AAS88422.1 xref: EMBL:BAA25751.1 xref: EMBL:CAH73681.1 xref: EMBL:CAI21385.1 xref: EMBL:CAI23601.1 xref: UniProtKB:O60260 xref: UniProtKB:Q5TFV8 xref: UniProtKB:Q6Q2I6 xref: UniProtKB:Q8NI41 xref: UniProtKB:Q8NI43 xref: UniProtKB:Q8NI44 xref: UniProtKB:Q8WW07 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005377 ! PARK2_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0008311 ! rgs2-park2 physical interaction relationship: participates_in CCO:I0008415 ! park2-rad1 physical interaction relationship: participates_in CCO:I0020395 ! park2-rac1 physical interaction [Term] id: CCO:B0006228 name: GLU2B_HUMAN def: "Glucosidase 2 subunit beta precursor" [UniProtKB:P14314] synonym: "80K-H protein" EXACT [UniProtKB:P14314] synonym: "Glucosidase II subunit beta" EXACT [UniProtKB:P14314] synonym: "PKCSH" EXACT [UniProtKB:P14314] synonym: "Protein kinase C substrate, 60.1 kDa protein, heavy chain" EXACT [UniProtKB:P14314] xref: EMBL:AAA52493.1 xref: EMBL:AAA98668.1 xref: EMBL:AAF66686.1 xref: EMBL:AAH13586.1 xref: EMBL:AAH15154.1 xref: EMBL:AAP88860.1 xref: UniProtKB:P14314 xref: UniProtKB:Q96BU9 xref: UniProtKB:Q96D06 xref: UniProtKB:Q9P0W9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004704 ! PRKCSH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008312 ! rgs2-prkcsh physical interaction relationship: participates_in CCO:I0020233 ! arf4l-prkcsh physical interaction relationship: participates_in CCO:I0020262 ! c7orf20-prkcsh physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0011942 ! GLU2B_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0011943 ! GLU2B_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0011944 ! GLU2B_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0011945 ! GLU2B_HUMAN-Phosphoserine434 [Term] id: CCO:B0006229 name: RIT1_HUMAN def: "GTP-binding protein Rit1" [UniProtKB:Q92963] synonym: "Ras-like protein expressed in many tissues" EXACT [UniProtKB:Q92963] synonym: "Ras-like without CAAX protein 1" EXACT [UniProtKB:Q92963] xref: EMBL:AAB42213.1 xref: EMBL:AAB64246.1 xref: EMBL:AAD13021.1 xref: EMBL:AAM12637.1 xref: EMBL:CAA68851.1 xref: UniProtKB:O00646 xref: UniProtKB:O00720 xref: UniProtKB:Q92963 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005495 ! RIT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008313 ! rit1-ptn physical interaction relationship: participates_in CCO:I0008314 ! rit1-rif1 physical interaction relationship: participates_in CCO:I0017305 ! hras-rgl1 physical interaction relationship: participates_in CCO:I0017306 ! rit1-rgl1 physical interaction relationship: participates_in CCO:I0017307 ! rgl1-rit1 physical interaction relationship: participates_in CCO:I0018586 ! rit-af6 physical interaction relationship: participates_in CCO:I0020652 ! rit1-ap2a1 physical interaction relationship: participates_in CCO:I0020653 ! rit1-ifrd1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0006230 name: RNF10_HUMAN def: "RING finger protein 10" [UniProtKB:Q8N5U6] xref: EMBL:AAH16622.1 xref: EMBL:AAH31596.1 xref: EMBL:AAI01710.1 xref: EMBL:AAI01716.1 xref: EMBL:AAP35620.1 xref: EMBL:BAA13392.2 xref: EMBL:BAA84708.1 xref: EMBL:CAB97533.1 xref: UniProtKB:Q8N5U6 xref: UniProtKB:Q92550 xref: UniProtKB:Q9NPP8 xref: UniProtKB:Q9ULW4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005519 ! RNF10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008315 ! rnf10-rif1 physical interaction relationship: participates_in CCO:I0019812 ! rnf10-setdb1 physical interaction relationship: participates_in CCO:I0019813 ! rnf10-tle1 physical interaction [Term] id: CCO:B0006231 name: RL37A_HUMAN def: "60S ribosomal protein L37a" [UniProtKB:P61513] xref: EMBL:AAA60280.1 xref: EMBL:AAH00555.2 xref: EMBL:AAH14262.1 xref: EMBL:AAH16748.1 xref: EMBL:AAH82239.1 xref: EMBL:CAA47244.1 xref: UniProtKB:P12751 xref: UniProtKB:P61513 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005506 ! RPL37A_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008317 ! rpl37a-rif1 physical interaction relationship: participates_in CCO:I0016639 ! map3k1-rpl37a physical interaction [Term] id: CCO:B0006232 name: RIR1_HUMAN def: "Ribonucleoside-diphosphate reductase large subunit" [UniProtKB:P23921] synonym: "EC 1.17.4.1" EXACT [UniProtKB:P23921] synonym: "Ribonucleoside-diphosphate reductase subunit M1" EXACT [UniProtKB:P23921] synonym: "Ribonucleotide reductase large subunit" EXACT [UniProtKB:P23921] xref: EMBL:AAD37491.1 xref: EMBL:AAH06498.1 xref: EMBL:CAA42118.1 xref: EMBL:CAA42180.1 xref: UniProtKB:P23921 xref: UniProtKB:Q9UNN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005494 ! RRM1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001113 ! ribonucleoside-diphosphate reductase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000518 ! ribonucleoside-diphosphate reductase complex relationship: participates_in CCO:I0008318 ! rrm1-rif1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0006233 name: PDPK1_HUMAN def: "3-phosphoinositide-dependent protein kinase 1" [UniProtKB:O15530] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O15530] synonym: "hPDK1" EXACT [UniProtKB:O15530] xref: EMBL:AAC51825.1 xref: EMBL:AAH12103.1 xref: EMBL:CAA75341.1 xref: UniProtKB:O15530 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005294 ! PDPK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008320 ! pnn-pdpk1 physical interaction relationship: participates_in CCO:I0020624 ! pdpk1-cdan1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0013476 ! PDPK1_HUMAN-Phosphotyrosine9 relationship: transforms_into CCO:B0013477 ! PDPK1_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0013478 ! PDPK1_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0013479 ! PDPK1_HUMAN-Phosphothreonine245 relationship: transforms_into CCO:B0013480 ! PDPK1_HUMAN-Phosphotyrosine373 relationship: transforms_into CCO:B0013481 ! PDPK1_HUMAN-Phosphotyrosine376 relationship: transforms_into CCO:B0013482 ! PDPK1_HUMAN-Phosphoserine393 relationship: transforms_into CCO:B0013483 ! PDPK1_HUMAN-Phosphoserine396 relationship: transforms_into CCO:B0013484 ! PDPK1_HUMAN-Phosphoserine410 [Term] id: CCO:B0006235 name: SNCAP_HUMAN def: "Synphilin-1" [UniProtKB:Q9Y6H5] synonym: "Alpha-synuclein-interacting protein" EXACT [UniProtKB:Q9Y6H5] xref: EMBL:AAD30362.1 xref: EMBL:AAG17478.1 xref: EMBL:EAW48889.1 xref: UniProtKB:Q9HC59 xref: UniProtKB:Q9Y6H5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005643 ! SNCAIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008322 ! sncaip-ptn physical interaction relationship: participates_in CCO:I0020457 ! sncaip-c7orf20 physical interaction relationship: participates_in CCO:I0020458 ! sncaip-sh2d3c physical interaction relationship: participates_in CCO:I0020666 ! sncaip-aes physical interaction relationship: participates_in CCO:I0020667 ! sncaip-agxt physical interaction relationship: participates_in CCO:P0002749 ! regulation of neurotransmitter secretion relationship: transforms_into CCO:B0070678 ! SNCAP_HUMAN-Phosphothreonine387 [Term] id: CCO:B0006236 name: SPG7_HUMAN def: "Paraplegin" [UniProtKB:Q9UQ90] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q9UQ90] synonym: "Spastic paraplegia protein 7" EXACT [UniProtKB:Q9UQ90] xref: EMBL:AAD28099.1 xref: EMBL:AAH35929.1 xref: EMBL:AAH36104.1 xref: EMBL:CAA76314.1 xref: UniProtKB:O75756 xref: UniProtKB:Q2TB70 xref: UniProtKB:Q58F00 xref: UniProtKB:Q96IB0 xref: UniProtKB:Q9UQ90 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005658 ! SPG7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008323 ! spg7-rif1 physical interaction relationship: participates_in CCO:I0015465 ! mdfi-spg7 physical interaction relationship: participates_in CCO:I0020208 ! trim28-spg7 physical interaction relationship: transforms_into CCO:B0014175 ! SPG7_HUMAN-Nitrated tyrosine505 [Term] id: CCO:B0006237 name: STC2_HUMAN def: "Stanniocalcin-2 precursor" [UniProtKB:O76061] synonym: "Stanniocalcin-related protein" EXACT [UniProtKB:O76061] synonym: "STC-2" EXACT [UniProtKB:O76061] synonym: "STC-related protein" EXACT [UniProtKB:O76061] synonym: "STCRP" EXACT [UniProtKB:O76061] xref: EMBL:AAC27036.1 xref: EMBL:AAC97948.1 xref: EMBL:AAD01922.1 xref: EMBL:AAH00658.1 xref: EMBL:AAH06352.1 xref: EMBL:AAH13958.1 xref: EMBL:AAV38398.1 xref: EMBL:BAA33489.1 xref: UniProtKB:O76061 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005689 ! STC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008325 ! stc2-ptn physical interaction relationship: participates_in CCO:I0019793 ! polr2c-stc2 physical interaction relationship: participates_in CCO:I0019795 ! polr3f-stc2 physical interaction relationship: participates_in CCO:I0019900 ! arrb2-stc2 physical interaction relationship: participates_in CCO:I0020095 ! pbp-stc2 physical interaction relationship: participates_in CCO:I0020101 ! pdcd8-stc2 physical interaction relationship: participates_in CCO:I0020123 ! ppp1r8-stc2 physical interaction relationship: participates_in CCO:I0020221 ! adam11-stc2 physical interaction relationship: participates_in CCO:I0020267 ! carhsp1-stc2 physical interaction relationship: participates_in CCO:I0020300 ! eif2b3-stc2 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0014248 ! STC2_HUMAN-Phosphothreonine28 [Term] id: CCO:B0006238 name: Q6GVN4_HUMAN def: "Hepatocellular carcinoma-associated antigen 59" [UniProtKB:Q6GVN4] xref: EMBL:AAT46619.1 xref: UniProtKB:Q6GVN4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006005 ! C9orf78_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008327 ! supt5h-c9orf78 physical interaction [Term] id: CCO:B0006239 name: RED_HUMAN def: "Protein Red" [UniProtKB:Q13123] synonym: "Cytokine IK" EXACT [UniProtKB:Q13123] synonym: "IK factor" EXACT [UniProtKB:Q13123] synonym: "Protein RER" EXACT [UniProtKB:Q13123] xref: EMBL:AAB32531.1 xref: EMBL:CAA06607.1 xref: UniProtKB:Q13123 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005463 ! IK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008329 ! supt5h-ik physical interaction relationship: participates_in CCO:I0019744 ! ik-chd3 physical interaction relationship: participates_in CCO:I0019745 ! ik-htatip physical interaction relationship: participates_in CCO:I0020040 ! ik-pfn2 physical interaction relationship: participates_in CCO:I0020390 ! nup62-ik physical interaction relationship: transforms_into CCO:B0013818 ! RED_HUMAN-Phosphothreonine485 relationship: transforms_into CCO:B0069853 ! RED_HUMAN-Phosphoserine460 [Term] id: CCO:B0006240 name: PNO1_HUMAN def: "RNA-binding protein PNO1" [UniProtKB:Q9NRX1] xref: EMBL:AAF80763.1 xref: EMBL:AAH08304.1 xref: EMBL:AAH18152.1 xref: EMBL:AAK29434.1 xref: EMBL:AAY14714.1 xref: EMBL:BAD96838.1 xref: UniProtKB:Q53G13 xref: UniProtKB:Q8WVB8 xref: UniProtKB:Q9NRX1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005349 ! PNO1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0008330 ! supt5h-loc56902 physical interaction relationship: participates_in CCO:I0019952 ! klf6-loc56902 physical interaction relationship: participates_in CCO:I0020018 ! gstp1-loc56902 physical interaction relationship: participates_in CCO:I0020576 ! igfbp5-loc56902 physical interaction relationship: participates_in CCO:I0020661 ! rxrg-loc56902 physical interaction [Term] id: CCO:B0006241 name: PHYIP_HUMAN def: "Phytanoyl-CoA hydroxylase-interacting protein" [UniProtKB:Q92561] synonym: "PAHX-AP1" EXACT [UniProtKB:Q92561] synonym: "PAHXAP1" EXACT [UniProtKB:Q92561] synonym: "Phytanoyl-CoA hydroxylase-associated protein 1" EXACT [UniProtKB:Q92561] xref: EMBL:AAH34034.1 xref: EMBL:AAH35940.1 xref: EMBL:BAA13402.2 xref: UniProtKB:Q8N4I9 xref: UniProtKB:Q92561 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005309 ! PHYHIP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008331 ! supt5h-phyhip physical interaction relationship: participates_in CCO:I0008416 ! phyhip-skb1 physical interaction relationship: participates_in CCO:I0020110 ! phyhip-med8 physical interaction relationship: participates_in CCO:I0020401 ! phyhip-hdac11 physical interaction relationship: participates_in CCO:I0020402 ! phyhip-ppie physical interaction relationship: participates_in CCO:I0020403 ! phyhip-smarcc2 physical interaction relationship: participates_in CCO:I0020625 ! phyhip-nfe2 physical interaction [Term] id: CCO:B0006242 name: TKNK_HUMAN def: "Tachykinin-3 precursor" [UniProtKB:Q9UHF0] synonym: "ZNEUROK1" EXACT [UniProtKB:Q9UHF0] xref: EMBL:AAF01430.1 xref: EMBL:AAF76980.1 xref: EMBL:AAH32145.1 xref: EMBL:AAQ10783.1 xref: EMBL:AAQ10784.1 xref: EMBL:AAQ10785.1 xref: EMBL:AAQ10786.1 xref: EMBL:AAQ10787.1 xref: EMBL:AAQ10788.1 xref: EMBL:AAQ10789.1 xref: EMBL:AAQ10790.1 xref: EMBL:AAQ10791.1 xref: EMBL:AAQ89042.1 xref: EMBL:CAG33474.1 xref: UniProtKB:Q6IAG2 xref: UniProtKB:Q71BC6 xref: UniProtKB:Q71BC9 xref: UniProtKB:Q9UHF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005787 ! TAC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008333 ! tac3-ptn physical interaction relationship: participates_in CCO:I0020181 ! tac3-fez1 physical interaction relationship: participates_in CCO:I0020182 ! tac3-ikbkap physical interaction relationship: participates_in CCO:I0020183 ! tac3-ubr1 physical interaction relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0014388 ! TKNK_HUMAN-Methionine amide90 [Term] id: CCO:B0006243 name: RFX1_HUMAN def: "MHC class II regulatory factor RFX1" [UniProtKB:P22670] synonym: "EF-C" EXACT [UniProtKB:P22670] synonym: "Enhancer factor C" EXACT [UniProtKB:P22670] synonym: "Regulatory factor X 1" EXACT [UniProtKB:P22670] synonym: "RFX" EXACT [UniProtKB:P22670] synonym: "Transcription factor RFX1" EXACT [UniProtKB:P22670] xref: EMBL:AAH49826.1 xref: EMBL:CAA41730.1 xref: UniProtKB:P22670 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005476 ! RFX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008335 ! tada3l-rfx1 physical interaction relationship: participates_in CCO:I0019446 ! hdac1-rfx1 physical interaction relationship: participates_in CCO:I0020062 ! maged1-rfx1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0013836 ! RFX1_HUMAN-Phosphoserine120 [Term] id: CCO:B0006244 name: TDGF1_HUMAN def: "Teratocarcinoma-derived growth factor 1 precursor" [UniProtKB:P13385] synonym: "CRGF" EXACT [UniProtKB:P13385] synonym: "Cripto-1 growth factor" EXACT [UniProtKB:P13385] synonym: "Epidermal growth factor-like cripto protein CR1" EXACT [UniProtKB:P13385] xref: EMBL:AAA61134.1 xref: EMBL:CAA32467.1 xref: UniProtKB:P13385 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005756 ! TDGF1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000899 ! extrinsic to plasma membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0008336 ! tdgf1-rif1 physical interaction relationship: participates_in CCO:I0020186 ! tdgf1-ang physical interaction relationship: participates_in CCO:I0020187 ! tdgf1-cops6 physical interaction relationship: participates_in CCO:I0020188 ! tdgf1-gdf9 physical interaction relationship: participates_in CCO:I0020476 ! tdgf1-bat3 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0006245 name: TINF2_HUMAN def: "TERF1-interacting nuclear factor 2" [UniProtKB:Q9BSI4] synonym: "TRF1-interacting nuclear protein 2" EXACT [UniProtKB:Q9BSI4] xref: EMBL:AAF18439.1 xref: EMBL:AAH05030.1 xref: EMBL:AAH19343.1 xref: EMBL:BAB14440.1 xref: UniProtKB:Q9BSI4 xref: UniProtKB:Q9H904 xref: UniProtKB:Q9UHC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005783 ! TINF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007131 ! terf2ip-rad50 physical interaction relationship: participates_in CCO:I0008338 ! terf1-tinf2 physical interaction relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: transforms_into CCO:B0071407 ! TINF2_HUMAN-Phosphoserine295 [Term] id: CCO:B0006246 name: TGIF1_HUMAN def: "Homeobox protein TGIF1" [UniProtKB:Q15583] synonym: "5'-TG-3'-interacting factor 1" EXACT [UniProtKB:Q15583] xref: EMBL:AAF81643.1 xref: EMBL:AAH00814.1 xref: EMBL:AAH31268.1 xref: EMBL:CAA61897.1 xref: EMBL:CAG29329.1 xref: UniProtKB:Q15583 xref: UniProtKB:Q6ICR0 xref: UniProtKB:Q8N5X9 xref: UniProtKB:Q9NRS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005777 ! TGIF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008339 ! tgif-rif1 physical interaction relationship: participates_in CCO:I0015506 ! ctbp2-tgif physical interaction relationship: participates_in CCO:I0019851 ! tgif-med31 physical interaction relationship: participates_in CCO:I0019852 ! tgif-eef1a1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0006247 name: Q6IAN9_HUMAN def: "TM4SF6 protein" [UniProtKB:Q6IAN9] synonym: "Tetraspanin 6, isoform CRA_b" EXACT [UniProtKB:Q6IAN9] xref: EMBL:CAG33396.1 xref: EMBL:EAX02811.1 xref: UniProtKB:Q6IAN9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006007 ! TM4SF6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008340 ! tm4sf6-rif1 physical interaction relationship: participates_in CCO:I0020481 ! tm4sf6-chd3 physical interaction [Term] id: CCO:B0006248 name: RM20_HUMAN def: "39S ribosomal protein L20, mitochondrial precursor" [UniProtKB:Q9BYC9] synonym: "L20mt" EXACT [UniProtKB:Q9BYC9] synonym: "MRP-L20" EXACT [UniProtKB:Q9BYC9] xref: EMBL:AAH09515.1 xref: EMBL:AAH14316.1 xref: EMBL:AAH59945.1 xref: EMBL:BAB40849.1 xref: EMBL:CAI22658.1 xref: UniProtKB:Q9BYC9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005514 ! MRPL20_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008343 ! tp53bp2-mrpl20 physical interaction relationship: participates_in CCO:I0008366 ! calm1-mrpl20 physical interaction relationship: participates_in CCO:I0019991 ! eps8-mrpl20 physical interaction relationship: participates_in CCO:I0020047 ! itsn1-mrpl20 physical interaction relationship: participates_in CCO:I0020266 ! capzb-mrpl20 physical interaction [Term] id: CCO:B0006249 name: CG036_HUMAN def: "Uncharacterized protein C7orf36" [UniProtKB:Q9NRH1] xref: EMBL:AAF86946.1 xref: EMBL:AAH22043.1 xref: EMBL:AAQ96864.1 xref: EMBL:CAG33479.1 xref: UniProtKB:Q6IAF7 xref: UniProtKB:Q8WVZ5 xref: UniProtKB:Q9NRH1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004338 ! C7orf36_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008344 ! tpd52l1-c7orf36 physical interaction relationship: participates_in CCO:I0019680 ! c7orf36-chd3 physical interaction [Term] id: CCO:B0006251 name: Q8N3Z8_HUMAN def: "TRBV21-1 protein" [UniProtKB:Q8N3Z8] xref: EMBL:AAH36926.1 xref: UniProtKB:Q8N3Z8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006022 ! TRBV21-1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008346 ! trbv21_1-rif1 physical interaction relationship: participates_in CCO:I0020207 ! trbv21_1-setdb1 physical interaction [Term] id: CCO:B0006252 name: ULK2_HUMAN def: "Serine/threonine-protein kinase ULK2" [UniProtKB:Q8IYT8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8IYT8] synonym: "Unc-51-like kinase 2" EXACT [UniProtKB:Q8IYT8] xref: EMBL:AAH34988.1 xref: EMBL:BAA31598.2 xref: UniProtKB:O75119 xref: UniProtKB:Q8IYT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005882 ! ULK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008350 ! ulk2-nasp physical interaction relationship: participates_in CCO:I0019873 ! ulk2-luc7l2 physical interaction relationship: participates_in CCO:I0019874 ! ulk2-setdb1 physical interaction relationship: participates_in CCO:I0020492 ! ulk2-pola2 physical interaction relationship: participates_in CCO:I0020683 ! ulk2-eef1b2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006253 name: ZCH10_HUMAN def: "Zinc finger CCHC domain-containing protein 10" [UniProtKB:Q8TBK6] xref: EMBL:AAH05211.1 xref: EMBL:AAH22443.1 xref: EMBL:BAA90946.1 xref: UniProtKB:Q8TBK6 xref: UniProtKB:Q9NXR4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005954 ! ZCCHC10_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008351 ! zcchc10-tp53 physical interaction relationship: participates_in CCO:I0008447 ! zcchc10-pin1 physical interaction relationship: participates_in CCO:I0008679 ! psme3-zcchc10 physical interaction [Term] id: CCO:B0006254 name: ZNF7_HUMAN def: "Zinc finger protein 7" [UniProtKB:P17097] synonym: "Zinc finger protein HF.16" EXACT [UniProtKB:P17097] synonym: "Zinc finger protein KOX4" EXACT [UniProtKB:P17097] xref: EMBL:AAA61313.1 xref: EMBL:AAH58923.1 xref: EMBL:CAA36561.1 xref: UniProtKB:P17015 xref: UniProtKB:P17097 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005969 ! ZNF7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008352 ! znf7-tada3l physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0006255 name: ABC3G_HUMAN def: "DNA dC->dU-editing enzyme APOBEC-3G" [UniProtKB:Q9HC16] synonym: "APOBEC-related cytidine deaminase" EXACT [UniProtKB:Q9HC16] synonym: "APOBEC-related protein" EXACT [UniProtKB:Q9HC16] synonym: "ARCD" EXACT [UniProtKB:Q9HC16] synonym: "ARP-9" EXACT [UniProtKB:Q9HC16] synonym: "CEM-15" EXACT [UniProtKB:Q9HC16] synonym: "CEM15" EXACT [UniProtKB:Q9HC16] synonym: "EC 3.5.4.-" EXACT [UniProtKB:Q9HC16] xref: EMBL:AAG14956.1 xref: EMBL:AAH24268.1 xref: EMBL:AAH61914.1 xref: EMBL:AAZ38722.1 xref: EMBL:BAB14251.1 xref: EMBL:CAB45274.1 xref: EMBL:CAG30358.1 xref: EMBL:CAI17900.1 xref: EMBL:CAI21556.1 xref: UniProtKB:Q45F02 xref: UniProtKB:Q5TF77 xref: UniProtKB:Q7Z2N1 xref: UniProtKB:Q7Z2N4 xref: UniProtKB:Q9H9H8 xref: UniProtKB:Q9HC16 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004010 ! APOBEC3G_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000597 ! cytidine deaminase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001073 ! apolipoprotein B mRNA editing enzyme complex relationship: participates_in CCO:I0008354 ! apobec3g-ptn physical interaction [Term] id: CCO:B0006256 name: ARL4D_HUMAN def: "ADP-ribosylation factor-like protein 4D" [UniProtKB:P49703] synonym: "ADP-ribosylation factor-like protein 4L" EXACT [UniProtKB:P49703] xref: EMBL:AAA57126.1 xref: EMBL:AAA93229.1 xref: EMBL:AAH00043.1 xref: EMBL:BAB91080.1 xref: UniProtKB:P49703 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004096 ! ARL4D_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008355 ! arf4l-eml4 physical interaction relationship: participates_in CCO:I0019559 ! arf4l-eif2b1 physical interaction relationship: participates_in CCO:I0019560 ! arf4l-tle1 physical interaction relationship: participates_in CCO:I0019561 ! arf4l-ubr1 physical interaction relationship: participates_in CCO:I0019562 ! arf4l-unc119 physical interaction relationship: participates_in CCO:I0019650 ! arf4l-snrpn physical interaction relationship: participates_in CCO:I0019896 ! arf4l-eprs physical interaction relationship: participates_in CCO:I0020229 ! arf4l-dnaja1 physical interaction relationship: participates_in CCO:I0020230 ! arf4l-mapk8ip3 physical interaction relationship: participates_in CCO:I0020231 ! arf4l-ndrg1 physical interaction relationship: participates_in CCO:I0020232 ! arf4l-pgam1 physical interaction relationship: participates_in CCO:I0020233 ! arf4l-prkcsh physical interaction relationship: participates_in CCO:I0020507 ! arf4l-mgc40499 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0006258 name: ARSE_HUMAN def: "Arylsulfatase E precursor" [UniProtKB:P51690] synonym: "ASE" EXACT [UniProtKB:P51690] synonym: "EC 3.1.6.-" EXACT [UniProtKB:P51690] xref: EMBL:BAD96903.1 xref: EMBL:BAD96919.1 xref: EMBL:CAA58556.1 xref: UniProtKB:P51690 xref: UniProtKB:Q53FT2 xref: UniProtKB:Q53FU8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004103 ! ARSE_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000540 ! arylsulfatase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001945 ! sulfuric ester hydrolase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:I0008359 ! arse-ndn physical interaction relationship: transforms_into CCO:B0010605 ! ARSE_HUMAN-3-oxoalanine (Cys)86 [Term] id: CCO:B0006259 name: BOC_HUMAN def: "Brother of CDO precursor" [UniProtKB:Q9BWV1] synonym: "Protein BOC" EXACT [UniProtKB:Q9BWV1] xref: EMBL:AAK14795.1 xref: EMBL:AAQ88694.1 xref: EMBL:BAC03436.1 xref: EMBL:BAC11057.1 xref: UniProtKB:A6NJ30 xref: UniProtKB:Q6UXJ5 xref: UniProtKB:Q8N2P7 xref: UniProtKB:Q8NF26 xref: UniProtKB:Q9BWV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004179 ! BOC_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008362 ! boc-rif1 physical interaction relationship: participates_in CCO:P0002477 ! positive regulation of myoblast differentiation [Term] id: CCO:B0006260 name: NEP1_HUMAN def: "Probable ribosome biogenesis protein NEP1" [UniProtKB:Q92979] synonym: "Nucleolar protein EMG1 homolog" EXACT [UniProtKB:Q92979] synonym: "Protein C2f" EXACT [UniProtKB:Q92979] xref: EMBL:AAB51325.1 xref: EMBL:AAC51641.1 xref: EMBL:AAH55314.1 xref: UniProtKB:O00675 xref: UniProtKB:O00726 xref: UniProtKB:Q92979 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005184 ! EMG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008364 ! c2f-khdrbs1 physical interaction relationship: participates_in CCO:I0008451 ! c2f-nat6 physical interaction relationship: participates_in CCO:I0008818 ! c2f-psmb7 physical interaction relationship: participates_in CCO:I0008819 ! c2f-psme1 physical interaction relationship: participates_in CCO:I0020520 ! c2f-anxa3 physical interaction relationship: participates_in CCO:I0020521 ! c2f-hivep1 physical interaction relationship: transforms_into CCO:B0013158 ! NEP1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0006261 name: MYO6_HUMAN def: "Myosin-VI" [UniProtKB:Q9UM54] synonym: "Unconventional myosin VI" EXACT [UniProtKB:Q9UM54] xref: EMBL:AAC51654.2 xref: EMBL:AAK00229.1 xref: EMBL:BAA20843.2 xref: EMBL:CAI19520.1 xref: EMBL:CAI19521.1 xref: EMBL:CAI19522.1 xref: EMBL:CAI42824.1 xref: EMBL:CAI42825.1 xref: EMBL:CAI42826.1 xref: UniProtKB:Q5TEM5 xref: UniProtKB:Q5TEM6 xref: UniProtKB:Q5TEM7 xref: UniProtKB:Q9BZZ7 xref: UniProtKB:Q9UEG2 xref: UniProtKB:Q9UM54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005146 ! MYO6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008367 ! calm1-myo6 physical interaction relationship: participates_in CCO:I0016479 ! ikbke-myo6 physical interaction relationship: participates_in CCO:I0016530 ! ikbkg-myo6 physical interaction relationship: participates_in CCO:I0016724 ! map3k3-myo6 physical interaction relationship: participates_in CCO:I0017019 ! tnfrsf1a-myo6 physical interaction relationship: participates_in CCO:I0017046 ! tnfrsf1b-myo6 physical interaction relationship: participates_in CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 [Term] id: CCO:B0006262 name: CD81_HUMAN def: "CD81 antigen" [UniProtKB:P60033] synonym: "26 kDa cell surface protein TAPA-1" EXACT [UniProtKB:P60033] synonym: "CD81 antigen" EXACT [UniProtKB:P60033] synonym: "Target of the antiproliferative antibody 1" EXACT [UniProtKB:P60033] synonym: "Tetraspanin-28" EXACT [UniProtKB:P60033] synonym: "Tspan-28" EXACT [UniProtKB:P60033] xref: EMBL:AAA36663.1 xref: EMBL:AAH02978.1 xref: EMBL:AAH93047.1 xref: EMBL:AAV38314.1 xref: EMBL:AAV38315.1 xref: EMBL:ABK41932.1 xref: UniProtKB:P18582 xref: UniProtKB:P60033 xref: UniProtKB:Q5U0J6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004282 ! CD81_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008368 ! cd81-dlg5 physical interaction relationship: participates_in CCO:I0020024 ! znhit4-cd81 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0006263 name: GLHA_HUMAN def: "Glycoprotein hormones alpha chain precursor" [UniProtKB:P01215] synonym: "Anterior pituitary glycoprotein hormones common subunit alpha" EXACT [UniProtKB:P01215] synonym: "CG-alpha" EXACT [UniProtKB:P01215] synonym: "Choriogonadotropin alpha chain" EXACT [UniProtKB:P01215] synonym: "Chorionic gonadotrophin alpha subunit" EXACT [UniProtKB:P01215] synonym: "Follicle-stimulating hormone alpha chain" EXACT [UniProtKB:P01215] synonym: "Follitropin alpha chain" EXACT [UniProtKB:P01215] synonym: "FSH-alpha" EXACT [UniProtKB:P01215] synonym: "LSH-alpha" EXACT [UniProtKB:P01215] synonym: "Luteinizing hormone alpha chain" EXACT [UniProtKB:P01215] synonym: "Lutropin alpha chain" EXACT [UniProtKB:P01215] synonym: "Thyroid-stimulating hormone alpha chain" EXACT [UniProtKB:P01215] synonym: "Thyrotropin alpha chain" EXACT [UniProtKB:P01215] synonym: "TSH-alpha" EXACT [UniProtKB:P01215] xref: EMBL:AAB30827.1 xref: EMBL:AAD13690.1 xref: EMBL:AAH20782.1 xref: EMBL:AAH55080.1 xref: EMBL:CAA23777.1 xref: UniProtKB:P01215 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004701 ! CGA_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0008374 ! cga-ptn physical interaction relationship: participates_in CCO:I0016197 ! cga-fshb-1 direct interaction relationship: participates_in CCO:I0018403 ! cga-fshb-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006264 name: CSN7A_HUMAN def: "COP9 signalosome complex subunit 7a" [UniProtKB:Q9UBW8] synonym: "Dermal papilla-derived protein 10" EXACT [UniProtKB:Q9UBW8] synonym: "JAB1-containing signalosome subunit 7a" EXACT [UniProtKB:Q9UBW8] synonym: "SGN7a" EXACT [UniProtKB:Q9UBW8] synonym: "Signalosome subunit 7a" EXACT [UniProtKB:Q9UBW8] xref: EMBL:AAF04307.1 xref: EMBL:AAF19205.1 xref: EMBL:AAH11789.1 xref: EMBL:BAA85390.1 xref: EMBL:BAA91620.1 xref: EMBL:BAB14052.1 xref: EMBL:BAB87805.1 xref: UniProtKB:Q9NVX3 xref: UniProtKB:Q9UBW8 xref: UniProtKB:Q9UJW4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004410 ! COPS7A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000530 ! signalosome relationship: participates_in CCO:I0008376 ! cops7a-ppbp physical interaction relationship: transforms_into CCO:B0011363 ! CSN7A_HUMAN-Phosphoserine232 [Term] id: CCO:B0006265 name: CELF1_HUMAN def: "CUG-BP- and ETR-3-like factor 1" [UniProtKB:Q92879] synonym: "50 kDa nuclear polyadenylated RNA-binding protein" EXACT [UniProtKB:Q92879] synonym: "Bruno-like protein 2" EXACT [UniProtKB:Q92879] synonym: "CELF-1" EXACT [UniProtKB:Q92879] synonym: "CUG triplet repeat RNA-binding protein 1" EXACT [UniProtKB:Q92879] synonym: "CUG-BP1" EXACT [UniProtKB:Q92879] synonym: "Deadenylation factor CUG-BP" EXACT [UniProtKB:Q92879] synonym: "EDEN-BP homolog" EXACT [UniProtKB:Q92879] synonym: "Embryo deadenylation element-binding protein homolog" EXACT [UniProtKB:Q92879] synonym: "RNA-binding protein BRUNOL-2" EXACT [UniProtKB:Q92879] xref: EMBL:AAC50895.1 xref: EMBL:AAF78955.1 xref: EMBL:AAF78956.1 xref: EMBL:AAF86230.1 xref: EMBL:AAH31079.1 xref: EMBL:BAE06101.1 xref: EMBL:CAC20566.1 xref: UniProtKB:Q4LE52 xref: UniProtKB:Q92879 xref: UniProtKB:Q9NP83 xref: UniProtKB:Q9NR06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004319 ! CUGBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008378 ! cugbp1-ppbp physical interaction relationship: participates_in CCO:I0019703 ! cugbp1-tom1l1 physical interaction relationship: participates_in CCO:I0020322 ! fubp1-cugbp1 physical interaction relationship: participates_in CCO:P0001122 ! RNA interference relationship: transforms_into CCO:B0011131 ! CELF1_HUMAN-Phosphoserine302 [Term] id: CCO:B0006267 name: DFNA5_HUMAN def: "Non-syndromic hearing impairment protein 5" [UniProtKB:O60443] synonym: "ICERE-1" EXACT [UniProtKB:O60443] synonym: "Inversely correlated with estrogen receptor expression 1" EXACT [UniProtKB:O60443] xref: EMBL:AAB83938.1 xref: EMBL:AAC39635.2 xref: EMBL:AAC69324.1 xref: EMBL:AAC69326.1 xref: EMBL:AAD20039.1 xref: EMBL:AAI25066.1 xref: UniProtKB:O14590 xref: UniProtKB:O60443 xref: UniProtKB:Q08AQ8 xref: UniProtKB:Q9UBV3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004465 ! DFNA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008380 ! dfna5-ptn physical interaction [Term] id: CCO:B0006268 name: ABCD4_HUMAN def: "ATP-binding cassette sub-family D member 4" [UniProtKB:O14678] synonym: "P70R" EXACT [UniProtKB:O14678] synonym: "Peroxisomal membrane protein 1-like" EXACT [UniProtKB:O14678] synonym: "Peroxisomal membrane protein 69" EXACT [UniProtKB:O14678] synonym: "PMP69" EXACT [UniProtKB:O14678] synonym: "PXMP1-L" EXACT [UniProtKB:O14678] xref: EMBL:AAB83967.1 xref: EMBL:AAH12815.1 xref: EMBL:AAP36080.1 xref: EMBL:CAA74699.1 xref: EMBL:CAG33385.1 xref: UniProtKB:O14678 xref: UniProtKB:Q6IAQ0 xref: UniProtKB:Q96E75 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004011 ! ABCD4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001725 ! ATP-binding cassette (ABC) transporter complex relationship: participates_in CCO:I0008381 ! dleu1-abcd4 physical interaction relationship: participates_in CCO:I0019888 ! abcd4-g22p1 physical interaction relationship: participates_in CCO:I0019889 ! abcd4-pea15 physical interaction [Term] id: CCO:B0006269 name: EFNA1_HUMAN def: "Ephrin-A1 precursor" [UniProtKB:P20827] synonym: "EPH-related receptor tyrosine kinase ligand 1" EXACT [UniProtKB:P20827] synonym: "Immediate early response protein B61" EXACT [UniProtKB:P20827] synonym: "LERK-1" EXACT [UniProtKB:P20827] synonym: "Tumor necrosis factor, alpha-induced protein 4" EXACT [UniProtKB:P20827] xref: EMBL:AAA58388.1 xref: EMBL:AAH32698.1 xref: EMBL:AAH95432.1 xref: EMBL:CAG33697.1 xref: EMBL:CAI15319.1 xref: EMBL:CAI15320.1 xref: UniProtKB:P20827 xref: UniProtKB:Q5SR60 xref: UniProtKB:Q5SR61 xref: UniProtKB:Q6I9T9 xref: UniProtKB:Q8N578 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004548 ! EFNA1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0006259 ! ephrin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0008384 ! efna1-ppbp physical interaction relationship: participates_in CCO:I0019983 ! efna1-htatip physical interaction [Term] id: CCO:B0006270 name: ENOG_HUMAN def: "Gamma-enolase" [UniProtKB:P09104] synonym: "2-phospho-D-glycerate hydro-lyase" EXACT [UniProtKB:P09104] synonym: "EC 4.2.1.11" EXACT [UniProtKB:P09104] synonym: "Enolase 2" EXACT [UniProtKB:P09104] synonym: "Neural enolase" EXACT [UniProtKB:P09104] synonym: "Neuron-specific enolase" EXACT [UniProtKB:P09104] synonym: "NSE" EXACT [UniProtKB:P09104] xref: EMBL:AAA52388.1 xref: EMBL:AAB51320.1 xref: EMBL:AAB59554.1 xref: EMBL:AAH02745.1 xref: EMBL:AAP36047.1 xref: EMBL:CAA31512.1 xref: EMBL:CAA32505.1 xref: EMBL:CAA36215.1 xref: UniProtKB:P09104 xref: UniProtKB:Q96J33 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004566 ! ENO2_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001008 ! phosphopyruvate hydratase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000001 ! phosphopyruvate hydratase complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008386 ! eno2-ube2c physical interaction relationship: participates_in CCO:I0019989 ! eno2-map4 physical interaction relationship: participates_in CCO:I0020302 ! eno2-hsf1 physical interaction relationship: participates_in CCO:I0020303 ! eno2-sigirr physical interaction relationship: transforms_into CCO:B0011694 ! ENOG_HUMAN-Phosphotyrosine44 relationship: transforms_into CCO:B0011695 ! ENOG_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0031315 ! ENOG_HUMAN-Phosphotyrosine25 [Term] id: CCO:B0006271 name: BTBDA_HUMAN def: "BTB/POZ domain-containing protein 10" [UniProtKB:Q9BSF8] xref: EMBL:AAH05071.2 xref: EMBL:AAO64360.1 xref: EMBL:CAH56329.1 xref: UniProtKB:Q86WG1 xref: UniProtKB:Q9BSF8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004194 ! BTBD10_human relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008390 ! btbd10-dlg5 physical interaction relationship: participates_in CCO:I0020563 ! btbd10-acin1 physical interaction relationship: participates_in CCO:I0020564 ! btbd10-lama5 physical interaction relationship: transforms_into CCO:B0010868 ! BTBDA_HUMAN-Phosphotyrosine377 [Term] id: CCO:B0006272 name: GOGB1_HUMAN def: "Golgin subfamily B member 1" [UniProtKB:Q14789] synonym: "372 kDa Golgi complex-associated protein" EXACT [UniProtKB:Q14789] synonym: "GCP372" EXACT [UniProtKB:Q14789] synonym: "Giantin" EXACT [UniProtKB:Q14789] synonym: "Macrogolgin" EXACT [UniProtKB:Q14789] xref: EMBL:BAA05025.1 xref: EMBL:CAA53052.1 xref: UniProtKB:Q14398 xref: UniProtKB:Q14789 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004715 ! GOLGB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008391 ! golgb1-brms1 physical interaction relationship: participates_in CCO:I0018844 ! golgb1-pfn2-1 physical interaction relationship: participates_in CCO:I0020012 ! golgb1-pfn2 physical interaction relationship: participates_in CCO:I0020567 ! golgb1-cav2 physical interaction relationship: participates_in CCO:I0020568 ! golgb1-vti1b physical interaction relationship: transforms_into CCO:B0066508 ! GOGB1_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0066509 ! GOGB1_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0066510 ! GOGB1_HUMAN-Phosphothreonine45 relationship: transforms_into CCO:B0066511 ! GOGB1_HUMAN-Phosphothreonine46 [Term] id: CCO:B0006273 name: GPAA1_HUMAN def: "Glycosylphosphatidylinositol anchor attachment 1 protein" [UniProtKB:O43292] synonym: "GAA1 protein homolog" EXACT [UniProtKB:O43292] synonym: "GPI anchor attachment protein 1" EXACT [UniProtKB:O43292] synonym: "hGAA1" EXACT [UniProtKB:O43292] xref: EMBL:AAH03171.1 xref: EMBL:AAH04129.1 xref: EMBL:AAH06383.2 xref: EMBL:BAA24035.1 xref: EMBL:BAA82587.1 xref: EMBL:BAA82588.1 xref: EMBL:BAA82590.1 xref: EMBL:CAB75660.2 xref: UniProtKB:O43292 xref: UniProtKB:Q9NSS0 xref: UniProtKB:Q9UQ31 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004721 ! GPAA1_human relationship: has_function CCO:F0000426 ! GPI-anchor transamidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_function CCO:F0005537 ! GPI anchor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001700 ! GPI-anchor transamidase complex relationship: participates_in CCO:I0008392 ! gpaa1-pin1 physical interaction relationship: participates_in CCO:I0020328 ! gpaa1-eif3s6 physical interaction [Term] id: CCO:B0006274 name: GOGA2_HUMAN def: "Golgin subfamily A member 2" [UniProtKB:Q08379] synonym: "Cis-Golgi matrix protein GM130" EXACT [UniProtKB:Q08379] synonym: "Gm130 autoantigen" EXACT [UniProtKB:Q08379] synonym: "Golgin-95" EXACT [UniProtKB:Q08379] xref: EMBL:AAA35920.1 xref: EMBL:AAF65550.1 xref: EMBL:AAH14188.2 xref: EMBL:AAH69268.1 xref: EMBL:AAP35912.1 xref: EMBL:CAI13841.1 xref: UniProtKB:Q08379 xref: UniProtKB:Q6GRM9 xref: UniProtKB:Q9BRB0 xref: UniProtKB:Q9NYF9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004714 ! GOLGA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008393 ! gps2-golga2 physical interaction relationship: participates_in CCO:I0015115 ! golga2-znf250 physical interaction relationship: participates_in CCO:I0015832 ! golga2-rab2 physical interaction relationship: participates_in CCO:I0015943 ! stk25-golga2-3 physical interaction relationship: participates_in CCO:I0015944 ! mst4-golga2-1 physical interaction relationship: participates_in CCO:I0018315 ! stk25-golga2-2 physical interaction relationship: participates_in CCO:I0018830 ! mst4-golga2-3 colocalization relationship: participates_in CCO:I0020500 ! znf594-golga2 physical interaction relationship: transforms_into CCO:B0011954 ! GOGA2_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0011955 ! GOGA2_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0011956 ! GOGA2_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0066507 ! GOGA2_HUMAN-Phosphoserine426 [Term] id: CCO:B0006275 name: HNRPL_HUMAN def: "Heterogeneous nuclear ribonucleoprotein L" [UniProtKB:P14866] synonym: "hnRNP L" EXACT [UniProtKB:P14866] xref: EMBL:BAB18649.1 xref: EMBL:CAA34261.1 xref: EMBL:EAW56828.1 xref: UniProtKB:A6ND69 xref: UniProtKB:P14866 xref: UniProtKB:Q9H3P3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006361 ! HNRNPL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0008395 ! hmg20b-hnrpl physical interaction relationship: participates_in CCO:I0020278 ! cse1l-hnrpl physical interaction relationship: participates_in CCO:I0020313 ! fgfr3-hnrpl physical interaction [Term] id: CCO:B0006276 name: TACC2_HUMAN def: "Transforming acidic coiled-coil-containing protein 2" [UniProtKB:O95359] synonym: "Anti Zuai-1" EXACT [UniProtKB:O95359] synonym: "AZU-1" EXACT [UniProtKB:O95359] xref: EMBL:AAC64968.2 xref: EMBL:AAF29537.2 xref: EMBL:AAF63433.1 xref: EMBL:AAH00999.1 xref: EMBL:AAH39311.1 xref: EMBL:AAO62629.1 xref: EMBL:AAO62630.1 xref: EMBL:CAD28509.1 xref: EMBL:CAI95127.1 xref: EMBL:CAI95128.1 xref: EMBL:CAI95131.1 xref: EMBL:CAI95134.1 xref: UniProtKB:O95359 xref: UniProtKB:Q4VXL0 xref: UniProtKB:Q4VXL3 xref: UniProtKB:Q4VXL6 xref: UniProtKB:Q4VXL7 xref: UniProtKB:Q5U5T7 xref: UniProtKB:Q86WG6 xref: UniProtKB:Q86WG7 xref: UniProtKB:Q8TCK9 xref: UniProtKB:Q9BVQ1 xref: UniProtKB:Q9NZ41 xref: UniProtKB:Q9NZR5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005722 ! TACC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008396 ! hmg20b-tacc2 physical interaction relationship: transforms_into CCO:B0014300 ! TACC2_HUMAN-Phosphoserine1946 relationship: transforms_into CCO:B0014301 ! TACC2_HUMAN-Phosphoserine1949 relationship: transforms_into CCO:B0014302 ! TACC2_HUMAN-Phosphoserine2256 relationship: transforms_into CCO:B0014303 ! TACC2_HUMAN-Phosphoserine2317 relationship: transforms_into CCO:B0014304 ! TACC2_HUMAN-Phosphoserine2512 [Term] id: CCO:B0006277 name: HNRH3_HUMAN def: "Heterogeneous nuclear ribonucleoprotein H3" [UniProtKB:P31942] synonym: "hnRNP 2H9" EXACT [UniProtKB:P31942] synonym: "hnRNP H3" EXACT [UniProtKB:P31942] xref: EMBL:AAD45179.1 xref: EMBL:AAF68843.1 xref: EMBL:AAF68844.1 xref: EMBL:AAF68845.1 xref: EMBL:AAF68846.1 xref: EMBL:AAF68847.1 xref: EMBL:AAF68848.1 xref: EMBL:AAF68849.1 xref: EMBL:AAF68850.1 xref: EMBL:AAF68851.1 xref: EMBL:AAF68852.1 xref: EMBL:AAH04511.2 xref: EMBL:AAH39824.1 xref: EMBL:CAB55897.1 xref: UniProtKB:P31942 xref: UniProtKB:Q9BSX1 xref: UniProtKB:Q9NP53 xref: UniProtKB:Q9NP96 xref: UniProtKB:Q9NPA7 xref: UniProtKB:Q9NPI4 xref: UniProtKB:Q9UFU4 xref: UniProtKB:Q9Y4J5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014351 ! HNRNPH3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008397 ! hnrph3-pim2 physical interaction relationship: participates_in CCO:I0008398 ! hnrph3-rps4x physical interaction relationship: participates_in CCO:I0019592 ! hnrph3-htatip physical interaction relationship: participates_in CCO:I0020574 ! hnrph3-ccl13 physical interaction relationship: transforms_into CCO:B0012209 ! HNRH3_HUMAN-Asymmetric dimethylarginine121 relationship: transforms_into CCO:B0012210 ! HNRH3_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0012211 ! HNRH3_HUMAN-Phosphotyrosine296 [Term] id: CCO:B0006279 name: SYK_HUMAN def: "Lysyl-tRNA synthetase" [UniProtKB:Q15046] synonym: "EC 6.1.1.6" EXACT [UniProtKB:Q15046] synonym: "Lysine--tRNA ligase" EXACT [UniProtKB:Q15046] synonym: "LysRS" EXACT [UniProtKB:Q15046] xref: EMBL:AAH04132.1 xref: EMBL:BAA06688.1 xref: EMBL:BAA22084.1 xref: UniProtKB:O14946 xref: UniProtKB:Q15046 xref: UniProtKB:Q96J25 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005714 ! KARS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008400 ! kars-pafah1b1 physical interaction relationship: participates_in CCO:I0016576 ! tank-kars physical interaction relationship: participates_in CCO:I0020579 ! kars-frs3 physical interaction relationship: transforms_into CCO:B0014274 ! SYK_HUMAN-Phosphoserine596 relationship: transforms_into CCO:B0041343 ! SYK_HUMAN-N-acetylalanine2 [Term] id: CCO:B0006280 name: K0087_HUMAN def: "Uncharacterized protein KIAA0087" [UniProtKB:Q14695] xref: EMBL:AAI28258.1 xref: EMBL:AAQ96877.1 xref: EMBL:BAA07639.2 xref: EMBL:EAL24233.1 xref: EMBL:EAW93856.1 xref: UniProtKB:A1A524 xref: UniProtKB:Q14695 xref: UniProtKB:Q75MW1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004914 ! KIAA0087_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008401 ! kiaa0087-tp53 physical interaction relationship: transforms_into CCO:B0012451 ! K0087_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0012452 ! K0087_HUMAN-Phosphoserine7 [Term] id: CCO:B0006281 name: MLP3A_HUMAN def: "Microtubule-associated proteins 1A/1B light chain 3A precursor" [UniProtKB:Q9H492] synonym: "Autophagy-related protein LC3 A" EXACT [UniProtKB:Q9H492] synonym: "Autophagy-related ubiquitin-like modifier LC3 A" EXACT [UniProtKB:Q9H492] synonym: "MAP1 light chain 3-like protein 1" EXACT [UniProtKB:Q9H492] synonym: "MAP1A/1B light chain 3 A" EXACT [UniProtKB:Q9H492] synonym: "MAP1A/MAP1B LC3 A" EXACT [UniProtKB:Q9H492] synonym: "Microtubule-associated protein 1 light chain 3 alpha" EXACT [UniProtKB:Q9H492] xref: EMBL:AAH15810.1 xref: EMBL:AAK35151.1 xref: EMBL:AAP36120.1 xref: EMBL:CAC14078.1 xref: EMBL:CAD38714.1 xref: EMBL:CAI40290.1 xref: UniProtKB:Q9BXW5 xref: UniProtKB:Q9H492 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005102 ! MAP1LC3A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001896 ! phosphatidylethanolamine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000358 ! autophagic vacuole relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001127 ! organelle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0008403 ! kif15-map1lc3a physical interaction [Term] id: CCO:B0006282 name: LYPA2_HUMAN def: "Acyl-protein thioesterase 2" [UniProtKB:O95372] synonym: "EC 3.1.2.-" EXACT [UniProtKB:O95372] synonym: "LPL-I" EXACT [UniProtKB:O95372] synonym: "Lysophospholipase II" EXACT [UniProtKB:O95372] xref: EMBL:AAC72844.1 xref: EMBL:AAH17034.1 xref: EMBL:AAH17193.1 xref: EMBL:AAP97210.1 xref: EMBL:CAB40158.1 xref: UniProtKB:O95372 xref: UniProtKB:Q7Z4Z2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004999 ! LYPLA2_human relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008404 ! lypla2-dkc1 physical interaction relationship: participates_in CCO:I0020056 ! lypla2-med31 physical interaction relationship: participates_in CCO:I0020360 ! lypla2-scmh1 physical interaction [Term] id: CCO:B0006283 name: TRP13_HUMAN def: "Thyroid receptor-interacting protein 13" [UniProtKB:Q15645] synonym: "16E1-BP" EXACT [UniProtKB:Q15645] synonym: "HPV16 E1 protein-binding protein" EXACT [UniProtKB:Q15645] synonym: "Human papillomavirus type 16 E1 protein-binding protein" EXACT [UniProtKB:Q15645] synonym: "Thyroid hormone receptor interactor 13" EXACT [UniProtKB:Q15645] synonym: "TRIP-13" EXACT [UniProtKB:Q15645] xref: EMBL:AAB64095.1 xref: EMBL:AAC41732.1 xref: EMBL:AAH00404.1 xref: EMBL:AAH19294.1 xref: EMBL:CAG33025.1 xref: UniProtKB:O15324 xref: UniProtKB:Q15645 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005836 ! TRIP13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008405 ! mad2l1bp-trip13-1 physical interaction relationship: transforms_into CCO:B0014537 ! TRP13_HUMAN-Phosphotyrosine56 [Term] id: CCO:B0006284 name: MKKS_HUMAN def: "McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin" [UniProtKB:Q9NPJ1] synonym: "Bardet-Biedl syndrome 6 protein" EXACT [UniProtKB:Q9NPJ1] xref: EMBL:AAF73872.1 xref: EMBL:AAF73873.1 xref: EMBL:CAB75652.1 xref: EMBL:CAC16847.1 xref: UniProtKB:Q9NPJ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005097 ! MKKS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0008406 ! mkks-ptn physical interaction [Term] id: CCO:B0006285 name: GRIK5_HUMAN def: "Glutamate receptor, ionotropic kainate 5 precursor" [UniProtKB:Q16478] synonym: "EAA2" EXACT [UniProtKB:Q16478] synonym: "Excitatory amino acid receptor 2" EXACT [UniProtKB:Q16478] synonym: "Glutamate receptor KA-2" EXACT [UniProtKB:Q16478] synonym: "KA2" EXACT [UniProtKB:Q16478] xref: EMBL:AAB22591.1 xref: EMBL:CAC80547.1 xref: EMBL:EAW57090.1 xref: UniProtKB:Q16478 xref: UniProtKB:Q8WWG8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004726 ! GRIK5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0002734 ! kainate selective glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0008407 ! mlf1-grik5 physical interaction [Term] id: CCO:B0006286 name: HPS6_HUMAN def: "Hermansky-Pudlak syndrome 6 protein" [UniProtKB:Q86YV9] synonym: "Ru" EXACT [UniProtKB:Q86YV9] synonym: "Ruby-eye protein homolog" EXACT [UniProtKB:Q86YV9] xref: EMBL:AAH11594.2 xref: EMBL:AAH14993.2 xref: EMBL:AAO25965.1 xref: EMBL:BAB15378.1 xref: UniProtKB:Q86YV9 xref: UniProtKB:Q9H685 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004827 ! HPS6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008408 ! mnat1-hps6 physical interaction relationship: participates_in CCO:I0020533 ! creb1-hps6 physical interaction relationship: participates_in CCO:I0020590 ! mark4-hps6 physical interaction [Term] id: CCO:B0006287 name: ERG28_HUMAN def: "Probable ergosterol biosynthetic protein 28" [UniProtKB:Q9UKR5] xref: EMBL:AAD51373.1 xref: EMBL:AAD54079.1 xref: EMBL:AAF28966.1 xref: EMBL:AAG49432.1 xref: EMBL:AAH02444.1 xref: EMBL:CAB66593.1 xref: UniProtKB:Q9P093 xref: UniProtKB:Q9UKR5 xref: UniProtKB:Q9UPI2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004583 ! C14orf1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000978 ! transport vesicle relationship: participates_in CCO:I0008409 ! mphosph6-c14orf1 physical interaction relationship: participates_in CCO:I0019537 ! hspe1-c14orf1 physical interaction relationship: participates_in CCO:I0019608 ! polr3f-c14orf1 physical interaction relationship: participates_in CCO:I0019688 ! cdc42-c14orf1 physical interaction relationship: participates_in CCO:I0019691 ! cdk5rap2-c14orf1 physical interaction relationship: participates_in CCO:I0019706 ! dncl1-c14orf1 physical interaction relationship: participates_in CCO:I0019788 ! pole2-c14orf1 physical interaction relationship: participates_in CCO:I0019827 ! serpinb9-c14orf1 physical interaction relationship: participates_in CCO:I0019856 ! tk1-c14orf1 physical interaction relationship: participates_in CCO:I0019882 ! znf24-c14orf1 physical interaction relationship: participates_in CCO:I0019942 ! ccl18-c14orf1 physical interaction relationship: participates_in CCO:I0019957 ! cradd-c14orf1 physical interaction relationship: participates_in CCO:I0019959 ! creb1-c14orf1 physical interaction relationship: participates_in CCO:I0020025 ! hmgb1-c14orf1 physical interaction relationship: participates_in CCO:I0020105 ! pfn1-c14orf1 physical interaction relationship: participates_in CCO:I0020120 ! ppp1r8-c14orf1 physical interaction relationship: participates_in CCO:I0020138 ! rab27a-c14orf1 physical interaction relationship: participates_in CCO:I0020190 ! tfg-c14orf1 physical interaction relationship: participates_in CCO:I0020255 ! baiap2-c14orf1 physical interaction relationship: participates_in CCO:I0020410 ! pqbp1-c14orf1 physical interaction relationship: participates_in CCO:I0020483 ! tnfrsf6-c14orf1 physical interaction relationship: participates_in CCO:I0020497 ! zfp64-c14orf1 physical interaction relationship: participates_in CCO:I0020552 ! fcgr2b-c14orf1 physical interaction [Term] id: CCO:B0006288 name: RT26_HUMAN def: "28S ribosomal protein S26, mitochondrial precursor" [UniProtKB:Q9BYN8] synonym: "MRP-S13" EXACT [UniProtKB:Q9BYN8] synonym: "MRP-S26" EXACT [UniProtKB:Q9BYN8] synonym: "S26mt" EXACT [UniProtKB:Q9BYN8] xref: EMBL:AAH13018.1 xref: EMBL:BAB54943.1 xref: EMBL:CAC10339.2 xref: UniProtKB:Q96Q58 xref: UniProtKB:Q9BYN8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005546 ! MRPS26_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000346 ! mitochondrial small ribosomal subunit relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008411 ! mrps26-ppp2ca physical interaction [Term] id: CCO:B0006289 name: NDUB8_HUMAN def: "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial precursor" [UniProtKB:O95169] synonym: "CI-ASHI" EXACT [UniProtKB:O95169] synonym: "Complex I-ASHI" EXACT [UniProtKB:O95169] synonym: "NADH-ubiquinone oxidoreductase ASHI subunit" EXACT [UniProtKB:O95169] xref: EMBL:AAD05422.1 xref: EMBL:AAD27761.1 xref: EMBL:AAH00466.1 xref: EMBL:AAH19276.1 xref: EMBL:AAP97239.1 xref: EMBL:CAB45691.1 xref: EMBL:CAB46274.1 xref: EMBL:CAG38521.1 xref: EMBL:CAH73563.1 xref: UniProtKB:O95169 xref: UniProtKB:Q5W144 xref: UniProtKB:Q9UG53 xref: UniProtKB:Q9UJR4 xref: UniProtKB:Q9UQF3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005170 ! NDUFB8_human relationship: has_function CCO:F0000447 ! NADH dehydrogenase activity relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008412 ! ndufb8-pim2 physical interaction relationship: participates_in CCO:I0020083 ! ndufb8-pfn2 physical interaction [Term] id: CCO:B0006291 name: PA1B2_HUMAN def: "Platelet-activating factor acetylhydrolase IB subunit beta" [UniProtKB:P68402] synonym: "EC 3.1.1.47" EXACT [UniProtKB:P68402] synonym: "PAF acetylhydrolase 30 kDa subunit" EXACT [UniProtKB:P68402] synonym: "PAF-AH 30 kDa subunit" EXACT [UniProtKB:P68402] synonym: "PAF-AH subunit beta" EXACT [UniProtKB:P68402] synonym: "PAFAH subunit beta" EXACT [UniProtKB:P68402] xref: EMBL:AAH00398.1 xref: EMBL:AAH19301.1 xref: EMBL:BAA19917.1 xref: UniProtKB:O00687 xref: UniProtKB:P68402 xref: UniProtKB:Q29459 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005250 ! PAFAH1B2_human relationship: has_function CCO:F0000366 ! 1-alkyl-2-acetylglycerophosphocholine esterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003360 ! hydrolase activity, acting on ester bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008414 ! pafah1b2-pinx1 physical interaction relationship: participates_in CCO:I0020393 ! pafah1b2-acin1 physical interaction relationship: participates_in CCO:I0020394 ! pafah1b2-zfp36l1 physical interaction [Term] id: CCO:B0006292 name: PLXB2_HUMAN def: "Plexin-B2 precursor" [UniProtKB:O15031] synonym: "MM1" EXACT [UniProtKB:O15031] xref: EMBL:AAH04542.2 xref: EMBL:AAP35533.1 xref: EMBL:BAA21571.1 xref: EMBL:CAO03498.1 xref: UniProtKB:A6QRH0 xref: UniProtKB:O15031 xref: UniProtKB:Q7KZU3 xref: UniProtKB:Q9BSU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005341 ! PLXNB2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008418 ! plxnb2-ptn physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0006293 name: Q53SQ6_HUMAN def: "Putative uncharacterized protein PTD004" [UniProtKB:Q53SQ6] xref: EMBL:AAY14876.1 xref: UniProtKB:Q53SQ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005992 ! PTD004_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008421 ! ptd004-skb1 physical interaction relationship: participates_in CCO:I0019663 ! ascc2-ptd004 physical interaction [Term] id: CCO:B0006294 name: PTOV1_HUMAN def: "Prostate tumor overexpressed gene 1 protein" [UniProtKB:Q86YD1] synonym: "Activator interaction domain-containing protein 2" EXACT [UniProtKB:Q86YD1] synonym: "PTOV-1" EXACT [UniProtKB:Q86YD1] xref: EMBL:AAF70635.1 xref: EMBL:AAG17268.1 xref: EMBL:AAH15172.1 xref: EMBL:AAH42921.1 xref: EMBL:AAQ88535.1 xref: EMBL:CAE84582.1 xref: EMBL:EAW52558.1 xref: UniProtKB:Q6UXX7 xref: UniProtKB:Q86YD1 xref: UniProtKB:Q96BU3 xref: UniProtKB:Q9HBN4 xref: UniProtKB:Q9NYL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005401 ! PTOV1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008423 ! ptov1-pin1 physical interaction relationship: participates_in CCO:I0020414 ! ptov1-epb49 physical interaction relationship: participates_in CCO:I0020415 ! ptov1-sptan1 physical interaction relationship: participates_in CCO:I0020636 ! ptov1-tmcc2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0006295 name: RAB4A_HUMAN def: "Ras-related protein Rab-4A" [UniProtKB:P20338] xref: EMBL:AAA60244.1 xref: EMBL:AAH02438.1 xref: EMBL:AAH04309.1 xref: EMBL:AAM21082.1 xref: EMBL:AAT91347.1 xref: EMBL:BAG36543.1 xref: EMBL:CAI19037.1 xref: EMBL:CAI22870.1 xref: EMBL:EAW69890.1 xref: UniProtKB:P20338 xref: UniProtKB:Q5T7P7 xref: UniProtKB:Q9BQ44 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005410 ! RAB4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008424 ! rab4a-tp53 physical interaction relationship: participates_in CCO:I0020645 ! rab4a-sod2 physical interaction relationship: transforms_into CCO:B0013657 ! RAB4A_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0013658 ! RAB4A_HUMAN-Cysteine methyl ester213 [Term] id: CCO:B0006296 name: WDR74_HUMAN def: "WD repeat-containing protein 74" [UniProtKB:Q6RFH5] synonym: "NOP seven-associated protein 1" EXACT [UniProtKB:Q6RFH5] xref: EMBL:AAH06351.1 xref: EMBL:AAS48499.1 xref: EMBL:BAA91610.1 xref: EMBL:BAB15122.1 xref: UniProtKB:Q6RFH5 xref: UniProtKB:Q9BRC9 xref: UniProtKB:Q9H6X8 xref: UniProtKB:Q9NVY2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005926 ! WDR74_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008427 ! rgs2-wdr74 physical interaction relationship: transforms_into CCO:B0071839 ! WDR74_HUMAN-Phosphoserine361 [Term] id: CCO:B0006298 name: NIPS1_HUMAN def: "Protein NipSnap homolog 1" [UniProtKB:Q9BPW8] synonym: "NipSnap1" EXACT [UniProtKB:Q9BPW8] xref: EMBL:AAH02371.1 xref: EMBL:AAH06473.1 xref: EMBL:CAA04632.1 xref: UniProtKB:O43800 xref: UniProtKB:Q9BPW8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005197 ! NIPSNAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: participates_in CCO:I0008429 ! rgs2-nipsnap1 physical interaction relationship: participates_in CCO:I0020607 ! nipsnap1-tbc1d17 physical interaction [Term] id: CCO:B0006299 name: VPS29_HUMAN def: "Vacuolar protein sorting-associated protein 29" [UniProtKB:Q9UBQ0] synonym: "EC 3.1.3.3" EXACT [UniProtKB:Q9UBQ0] synonym: "hVPS29" EXACT [UniProtKB:Q9UBQ0] synonym: "PEP11" EXACT [UniProtKB:Q9UBQ0] synonym: "Vesicle protein sorting 29" EXACT [UniProtKB:Q9UBQ0] xref: EMBL:AAF04596.1 xref: EMBL:AAF17238.1 xref: EMBL:AAF86872.1 xref: EMBL:AAF87318.1 xref: EMBL:AAF89952.1 xref: EMBL:AAH00880.1 xref: EMBL:AAH95446.1 xref: EMBL:CAB66549.1 xref: EMBL:CAG33463.1 xref: EMBL:CAG38499.1 xref: UniProtKB:Q502Y5 xref: UniProtKB:Q6FIF8 xref: UniProtKB:Q6IAH3 xref: UniProtKB:Q9H0W0 xref: UniProtKB:Q9NRP1 xref: UniProtKB:Q9NRU7 xref: UniProtKB:Q9UBQ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005905 ! VPS29_human relationship: has_function CCO:F0001020 ! phosphoserine phosphatase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008430 ! rgs2-vps29 physical interaction [Term] id: CCO:B0006300 name: RL18A_HUMAN def: "60S ribosomal protein L18a" [UniProtKB:Q02543] xref: EMBL:AAC18781.1 xref: EMBL:AAC62828.1 xref: EMBL:AAH07512.1 xref: EMBL:AAH66319.1 xref: EMBL:AAH71920.1 xref: EMBL:CAA56788.1 xref: UniProtKB:Q02543 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005499 ! RPL18A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008431 ! rpl18a-mdk physical interaction relationship: participates_in CCO:I0020505 ! aes-rpl18a physical interaction relationship: participates_in CCO:I0020588 ! map3k12-rpl18a physical interaction relationship: transforms_into CCO:B0013884 ! RL18A_HUMAN-Phosphotyrosine63 relationship: transforms_into CCO:B0013885 ! RL18A_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0070065 ! RL18A_HUMAN-Phosphoserine123 [Term] id: CCO:B0006301 name: ST65G_HUMAN def: "STAGA complex 65 subunit gamma" [UniProtKB:O94864] synonym: "Adenocarcinoma antigen ART1" EXACT [UniProtKB:O94864] synonym: "SPTF-associated factor 65 gamma" EXACT [UniProtKB:O94864] synonym: "STAF65gamma" EXACT [UniProtKB:O94864] synonym: "Suppressor of Ty 7-like" EXACT [UniProtKB:O94864] xref: EMBL:AAG28523.1 xref: EMBL:AAG47636.1 xref: EMBL:AAH74000.1 xref: EMBL:AAX93202.1 xref: EMBL:BAA34484.2 xref: EMBL:CAG33264.1 xref: UniProtKB:O94864 xref: UniProtKB:Q6IB21 xref: UniProtKB:Q9H2T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005679 ! SUPT7L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008433 ! supt7l-ptn physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0006302 name: DREB_HUMAN def: "Drebrin" [UniProtKB:Q16643] synonym: "Developmentally-regulated brain protein" EXACT [UniProtKB:Q16643] xref: EMBL:AAA16256.1 xref: EMBL:AAH00283.1 xref: EMBL:AAH07281.1 xref: EMBL:AAH07567.1 xref: EMBL:BAA04480.1 xref: EMBL:CAB53683.1 xref: UniProtKB:Q16643 xref: UniProtKB:Q9UFZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004512 ! DBN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008434 ! supt5h-dbn1 physical interaction relationship: participates_in CCO:I0008465 ! dbn1-nipbl physical interaction relationship: participates_in CCO:I0016492 ! ikbkg-dbn1 physical interaction relationship: participates_in CCO:I0016669 ! map3k3-dbn1 physical interaction relationship: participates_in CCO:P0002785 ! regulation of neuronal synaptic plasticity relationship: participates_in CCO:P0002951 ! regulation of dendrite development relationship: transforms_into CCO:B0011582 ! DREB_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0011583 ! DREB_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0011584 ! DREB_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0011585 ! DREB_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0011586 ! DREB_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0011587 ! DREB_HUMAN-Phosphoserine339 relationship: transforms_into CCO:B0011588 ! DREB_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0011589 ! DREB_HUMAN-Phosphothreonine346 relationship: transforms_into CCO:B0011590 ! DREB_HUMAN-Phosphotyrosine622 relationship: transforms_into CCO:B0048245 ! DREB_HUMAN-Phosphothreonine335 relationship: transforms_into CCO:B0064879 ! DREB_HUMAN-Phosphothreonine331 [Term] id: CCO:B0006303 name: TCEA2_HUMAN def: "Transcription elongation factor A protein 2" [UniProtKB:Q15560] synonym: "Testis-specific S-II" EXACT [UniProtKB:Q15560] synonym: "Transcription elongation factor S-II protein 2" EXACT [UniProtKB:Q15560] synonym: "Transcription elongation factor TFIIS.l" EXACT [UniProtKB:Q15560] xref: EMBL:AAC39553.1 xref: EMBL:AAH18896.1 xref: EMBL:BAA09089.1 xref: EMBL:CAD11900.1 xref: EMBL:CAD11901.1 xref: UniProtKB:Q15560 xref: UniProtKB:Q8TD37 xref: UniProtKB:Q8TD38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005748 ! TCEA2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: participates_in CCO:I0008436 ! tcea2-rpa1 physical interaction relationship: participates_in CCO:I0015684 ! magea11-tcea2 physical interaction relationship: participates_in CCO:I0015748 ! tcea2-traf2 physical interaction relationship: participates_in CCO:I0019405 ! mark3-tcea2-1 physical interaction relationship: participates_in CCO:I0019413 ! tcea2-magea11 physical interaction relationship: participates_in CCO:I0019973 ! dnajb9-tcea2 physical interaction relationship: participates_in CCO:I0020185 ! tcea2-mark3 physical interaction relationship: participates_in CCO:I0020470 ! tcea2-akt1s1 physical interaction relationship: participates_in CCO:I0020471 ! tcea2-fbf1 physical interaction relationship: participates_in CCO:I0020472 ! tcea2-wdr47 physical interaction relationship: participates_in CCO:I0020473 ! tcea2-sh3gl2 physical interaction relationship: participates_in CCO:I0020474 ! tcea2-tax1bp3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0006304 name: THAP8_HUMAN def: "THAP domain-containing protein 8" [UniProtKB:Q8NA92] xref: EMBL:AAH72416.1 xref: EMBL:BAB71493.1 xref: EMBL:BAC04034.1 xref: UniProtKB:Q8NA92 xref: UniProtKB:Q96M21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005778 ! THAP8_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008440 ! thap8-tp53 physical interaction relationship: participates_in CCO:I0020195 ! thap8-setdb1 physical interaction relationship: participates_in CCO:I0020480 ! thap8-dncl1 physical interaction [Term] id: CCO:B0006305 name: UBP4_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 4" [UniProtKB:Q13107] synonym: "Deubiquitinating enzyme 4" EXACT [UniProtKB:Q13107] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q13107] synonym: "Ubiquitin thioesterase 4" EXACT [UniProtKB:Q13107] synonym: "Ubiquitin-specific-processing protease 4" EXACT [UniProtKB:Q13107] synonym: "Ubiquitous nuclear protein homolog" EXACT [UniProtKB:Q13107] xref: EMBL:AAB72237.1 xref: EMBL:AAC27355.1 xref: EMBL:AAC27356.1 xref: EMBL:AAI25131.1 xref: UniProtKB:O43452 xref: UniProtKB:O43453 xref: UniProtKB:Q08AK8 xref: UniProtKB:Q13107 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005869 ! USP4_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:I0008442 ! tp53bp2-usp4 physical interaction [Term] id: CCO:B0006306 name: GP135_HUMAN def: "Probable G-protein coupled receptor 135" [UniProtKB:Q8IZ08] xref: EMBL:AAH32831.2 xref: EMBL:AAO85100.1 xref: EMBL:AAP72127.1 xref: EMBL:BAC05800.1 xref: UniProtKB:Q7Z604 xref: UniProtKB:Q86SM3 xref: UniProtKB:Q8IZ08 xref: UniProtKB:Q8NH39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004719 ! GPR135_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008443 ! tpd52l1-gpr135 physical interaction relationship: participates_in CCO:I0020061 ! maged1-gpr135 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0006307 name: DLGP4_HUMAN def: "Disks large-associated protein 4" [UniProtKB:Q9Y2H0] synonym: "DAP-4" EXACT [UniProtKB:Q9Y2H0] synonym: "PSD-95/SAP90-binding protein 4" EXACT [UniProtKB:Q9Y2H0] synonym: "SAP90/PSD-95-associated protein 4" EXACT [UniProtKB:Q9Y2H0] synonym: "SAPAP-4" EXACT [UniProtKB:Q9Y2H0] xref: EMBL:AAI08707.1 xref: EMBL:AAI53875.1 xref: EMBL:BAA76808.2 xref: EMBL:CAI17927.1 xref: EMBL:CAI17928.1 xref: EMBL:CAI17929.1 xref: EMBL:CAI23506.1 xref: EMBL:CAI23507.1 xref: EMBL:CAI23509.1 xref: EMBL:EAW76140.1 xref: UniProtKB:Q5QPG4 xref: UniProtKB:Q5T2Y4 xref: UniProtKB:Q5T2Y5 xref: UniProtKB:Q9H137 xref: UniProtKB:Q9H138 xref: UniProtKB:Q9H1L7 xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004481 ! DLGAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008468 ! dlgap4-plk2 physical interaction relationship: participates_in CCO:I0020407 ! ppp1r1b-dlgap4 physical interaction relationship: transforms_into CCO:B0064770 ! DLGP4_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0064771 ! DLGP4_HUMAN-Phosphotyrosine369 relationship: transforms_into CCO:B0064772 ! DLGP4_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0064773 ! DLGP4_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0064774 ! DLGP4_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0064775 ! DLGP4_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0064776 ! DLGP4_HUMAN-Phosphothreonine915 relationship: transforms_into CCO:B0064777 ! DLGP4_HUMAN-Phosphoserine973 relationship: transforms_into CCO:B0064778 ! DLGP4_HUMAN-Phosphotyrosine984 [Term] id: CCO:B0006308 name: WFDC2_HUMAN def: "WAP four-disulfide core domain protein 2 precursor" [UniProtKB:Q14508] synonym: "Epididymal secretory protein E4" EXACT [UniProtKB:Q14508] synonym: "Major epididymis-specific protein E4" EXACT [UniProtKB:Q14508] synonym: "Putative protease inhibitor WAP5" EXACT [UniProtKB:Q14508] xref: EMBL:AAH46106.1 xref: EMBL:AAL37485.1 xref: EMBL:AAL37486.1 xref: EMBL:AAL37487.1 xref: EMBL:AAL37488.1 xref: EMBL:AAO52683.1 xref: EMBL:CAA44869.1 xref: EMBL:CAB37641.1 xref: EMBL:CAG33258.1 xref: UniProtKB:Q14508 xref: UniProtKB:Q6IB27 xref: UniProtKB:Q8WXV9 xref: UniProtKB:Q8WXW0 xref: UniProtKB:Q8WXW1 xref: UniProtKB:Q8WXW2 xref: UniProtKB:Q96KJ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005930 ! WFDC2_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0004441 ! protease inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0008446 ! wfdc2-ptn physical interaction [Term] id: CCO:B0006309 name: TBL3_HUMAN def: "WD repeat-containing protein SAZD" [UniProtKB:Q12788] synonym: "Transducin beta-like 3 protein" EXACT [UniProtKB:Q12788] xref: EMBL:AAA18945.1 xref: UniProtKB:Q12788 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005743 ! TBL3_human relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008448 ! aurkb-tbl3 physical interaction relationship: participates_in CCO:I0020049 ! itsn2-tbl3 physical interaction relationship: participates_in CCO:I0020265 ! cacnb4-tbl3 physical interaction relationship: participates_in CCO:I0020524 ! c9orf74-tbl3 physical interaction relationship: participates_in CCO:I0020684 ! usp11-tbl3 physical interaction relationship: participates_in CCO:P0000737 ! G-protein signaling, coupled to cGMP nucleotide second messenger [Term] id: CCO:B0006310 name: SH3G1_HUMAN def: "Endophilin-A2" [UniProtKB:Q99961] synonym: "EEN" EXACT [UniProtKB:Q99961] synonym: "EEN fusion partner of MLL" EXACT [UniProtKB:Q99961] synonym: "Endophilin-2" EXACT [UniProtKB:Q99961] synonym: "Extra eleven-nineteen leukemia fusion gene protein" EXACT [UniProtKB:Q99961] synonym: "SH3 domain protein 2B" EXACT [UniProtKB:Q99961] synonym: "SH3 domain-containing GRB2-like protein 1" EXACT [UniProtKB:Q99961] xref: EMBL:AAB86800.1 xref: EMBL:AAF04290.1 xref: EMBL:AAH01270.1 xref: EMBL:CAA67970.1 xref: UniProtKB:Q99668 xref: UniProtKB:Q99961 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005607 ! SH3GL1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: participates_in CCO:I0008449 ! axin1-sh3gl1 physical interaction relationship: participates_in CCO:I0015207 ! sh3gl1-sh3gl1 physical interaction relationship: participates_in CCO:I0018512 ! cnsa1-cnsa2 physical interaction relationship: participates_in CCO:I0018518 ! cnsa2-cnsa1 physical interaction relationship: participates_in CCO:I0018519 ! cnsa3-cnsa1-1 physical interaction relationship: participates_in CCO:I0019407 ! sh3gl1-dppa4-1 physical interaction relationship: participates_in CCO:I0019834 ! sh3gl1-sh3gl3 physical interaction relationship: participates_in CCO:I0019979 ! dppa4-sh3gl1 physical interaction relationship: participates_in CCO:I0019980 ! sh3gl1-dppa4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0014053 ! SH3G1_HUMAN-Phosphoserine288 [Term] id: CCO:B0006311 name: BRD4_HUMAN def: "Bromodomain-containing protein 4" [UniProtKB:O60885] synonym: "HUNK1 protein" EXACT [UniProtKB:O60885] xref: EMBL:AAC27978.1 xref: EMBL:AAL26987.1 xref: EMBL:AAO22237.1 xref: EMBL:CAA72780.1 xref: UniProtKB:O60433 xref: UniProtKB:O60885 xref: UniProtKB:Q86YS8 xref: UniProtKB:Q96PD3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004188 ! BRD4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008450 ! brd4-chfr physical interaction relationship: transforms_into CCO:B0010861 ! BRD4_HUMAN-Phosphoserine470 relationship: transforms_into CCO:B0010862 ! BRD4_HUMAN-Phosphoserine601 relationship: transforms_into CCO:B0010863 ! BRD4_HUMAN-Phosphoserine1045 relationship: transforms_into CCO:B0010864 ! BRD4_HUMAN-Phosphoserine1117 [Term] id: CCO:B0006312 name: URM1_HUMAN def: "Ubiquitin-related modifier 1 homolog" [UniProtKB:Q9BTM9] xref: EMBL:AAH03581.1 xref: EMBL:CAI13493.1 xref: UniProtKB:Q9BTM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005886 ! URM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008453 ! cdc2l1-c9orf74 physical interaction relationship: participates_in CCO:I0019902 ! ascc2-c9orf74 physical interaction relationship: participates_in CCO:I0020524 ! c9orf74-tbl3 physical interaction [Term] id: CCO:B0006313 name: SRPRB_HUMAN def: "Signal recognition particle receptor subunit beta" [UniProtKB:Q9Y5M8] synonym: "Protein APMCF1" EXACT [UniProtKB:Q9Y5M8] synonym: "SR-beta" EXACT [UniProtKB:Q9Y5M8] xref: EMBL:AAD34888.3 xref: EMBL:AAH65299.1 xref: EMBL:BAB55176.1 xref: EMBL:BAC11675.1 xref: UniProtKB:Q8N2D8 xref: UniProtKB:Q9Y5M8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005672 ! SRPRB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008455 ! cdk5rap3-srprb physical interaction relationship: participates_in CCO:I0016407 ! nfkbib-srprb physical interaction [Term] id: CCO:B0006314 name: CA123_HUMAN def: "UPF0587 protein C1orf123" [UniProtKB:Q9NWV4] xref: EMBL:AAH10908.1 xref: EMBL:BAA91272.1 xref: EMBL:CAG33527.1 xref: EMBL:CAI18911.1 xref: UniProtKB:Q9NWV4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004201 ! C1orf123_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008456 ! cdkn1a-flj20580 physical interaction [Term] id: CCO:B0006315 name: NRK2_HUMAN def: "Nicotinamide riboside kinase 2" [UniProtKB:Q9NPI5] synonym: "EC 2.7.1.22" EXACT [UniProtKB:Q9NPI5] synonym: "EC 2.7.1.n4" EXACT [UniProtKB:Q9NPI5] synonym: "Integrin beta-1-binding protein 3" EXACT [UniProtKB:Q9NPI5] synonym: "MIBP" EXACT [UniProtKB:Q9NPI5] synonym: "Muscle integrin-binding protein" EXACT [UniProtKB:Q9NPI5] synonym: "Nicotinic acid riboside kinase 2" EXACT [UniProtKB:Q9NPI5] synonym: "NmR-K 2" EXACT [UniProtKB:Q9NPI5] synonym: "NRK 2" EXACT [UniProtKB:Q9NPI5] synonym: "Ribosylnicotinamide kinase 2" EXACT [UniProtKB:Q9NPI5] synonym: "Ribosylnicotinic acid kinase 2" EXACT [UniProtKB:Q9NPI5] synonym: "RNK 2" EXACT [UniProtKB:Q9NPI5] xref: EMBL:AAF26711.1 xref: EMBL:AAH93637.1 xref: EMBL:AAI01576.1 xref: EMBL:AAT11929.1 xref: EMBL:BAA91820.1 xref: EMBL:BAB14071.1 xref: EMBL:CAB96949.1 xref: UniProtKB:Q52M81 xref: UniProtKB:Q9NPI5 xref: UniProtKB:Q9NZK3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005213 ! ITGB1BP3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008457 ! cdkn1a-itgb1bp3 physical interaction [Term] id: CCO:B0006316 name: M2OM_HUMAN def: "Mitochondrial 2-oxoglutarate/malate carrier protein" [UniProtKB:Q02978] synonym: "OGCP" EXACT [UniProtKB:Q02978] synonym: "Solute carrier family 25 member 11" EXACT [UniProtKB:Q02978] xref: EMBL:AAC28637.1 xref: EMBL:AAH06508.1 xref: EMBL:AAH06519.1 xref: EMBL:AAH16294.1 xref: EMBL:AAH17170.1 xref: EMBL:CAA46905.1 xref: UniProtKB:O75537 xref: UniProtKB:Q02978 xref: UniProtKB:Q969P7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005003 ! SLC25A11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008458 ! cdkn1a-slc25a11 physical interaction relationship: transforms_into CCO:B0012714 ! M2OM_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0031338 ! M2OM_HUMAN-Phosphotyrosine102 relationship: transforms_into CCO:B0031339 ! M2OM_HUMAN-Phosphotyrosine202 [Term] id: CCO:B0006317 name: GABR1_HUMAN def: "Gamma-aminobutyric acid type B receptor subunit 1 precursor" [UniProtKB:Q9UBS5] synonym: "GABA-B receptor 1" EXACT [UniProtKB:Q9UBS5] synonym: "GABA-B-R1" EXACT [UniProtKB:Q9UBS5] synonym: "Gb1" EXACT [UniProtKB:Q9UBS5] xref: EMBL:AAC98508.1 xref: EMBL:AAH42598.1 xref: EMBL:AAH50532.2 xref: EMBL:CAA09031.1 xref: EMBL:CAA09939.1 xref: EMBL:CAA09940.1 xref: EMBL:CAA09941.1 xref: EMBL:CAA09980.1 xref: EMBL:CAA12359.1 xref: EMBL:CAA12360.1 xref: EMBL:CAA21453.1 xref: EMBL:CAA21454.1 xref: UniProtKB:O95375 xref: UniProtKB:O95468 xref: UniProtKB:O95975 xref: UniProtKB:O96022 xref: UniProtKB:Q86W60 xref: UniProtKB:Q9UBS5 xref: UniProtKB:Q9UQQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004680 ! GABBR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0008459 ! chfr-gabbr1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway relationship: transforms_into CCO:B0011919 ! GABR1_HUMAN-Phosphothreonine930 [Term] id: CCO:B0006318 name: ITAE_HUMAN def: "Integrin alpha-E precursor" [UniProtKB:P38570] synonym: "CD103 antigen" EXACT [UniProtKB:P38570] synonym: "HML-1 antigen" EXACT [UniProtKB:P38570] synonym: "Integrin alpha-IEL" EXACT [UniProtKB:P38570] synonym: "Mucosal lymphocyte 1 antigen" EXACT [UniProtKB:P38570] xref: EMBL:AAB59359.2 xref: EMBL:AAF43107.1 xref: EMBL:AAI13437.1 xref: EMBL:AAI17208.1 xref: UniProtKB:P38570 xref: UniProtKB:Q17RS6 xref: UniProtKB:Q9NZU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004904 ! ITGAE_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008460 ! chfr-itgae physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0006319 name: WDR47_HUMAN def: "WD repeat-containing protein 47" [UniProtKB:O94967] xref: EMBL:AAH34964.1 xref: EMBL:AAH39254.1 xref: EMBL:BAA74916.2 xref: EMBL:BAF82478.1 xref: EMBL:CAH71325.1 xref: EMBL:CAH71326.1 xref: EMBL:CAH71327.1 xref: EMBL:CAI14351.1 xref: EMBL:CAI14352.1 xref: EMBL:CAI14353.1 xref: EMBL:EAW56350.1 xref: EMBL:EAW56351.1 xref: UniProtKB:O94967 xref: UniProtKB:Q5TYV7 xref: UniProtKB:Q5TYV8 xref: UniProtKB:Q5TYV9 xref: UniProtKB:Q8IXT7 xref: UniProtKB:Q8IYU9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005920 ! WDR47_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008461 ! chfr-wdr47 physical interaction relationship: participates_in CCO:I0020472 ! tcea2-wdr47 physical interaction relationship: transforms_into CCO:B0048424 ! WDR47_HUMAN-Phosphothreonine542 [Term] id: CCO:B0006320 name: CHSS2_HUMAN def: "Chondroitin sulfate synthase 2" [UniProtKB:Q8IZ52] synonym: "Chondroitin glucuronyltransferase II" EXACT [UniProtKB:Q8IZ52] synonym: "Chondroitin-polymerizing factor" EXACT [UniProtKB:Q8IZ52] synonym: "EC 2.4.1.175" EXACT [UniProtKB:Q8IZ52] synonym: "EC 2.4.1.226" EXACT [UniProtKB:Q8IZ52] synonym: "Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II" EXACT [UniProtKB:Q8IZ52] synonym: "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II" EXACT [UniProtKB:Q8IZ52] synonym: "N-acetylgalactosaminyltransferase" EXACT [UniProtKB:Q8IZ52] xref: EMBL:AAH08878.2 xref: EMBL:AAH21223.2 xref: EMBL:AAH23531.1 xref: EMBL:AAQ88769.1 xref: EMBL:BAB15449.1 xref: EMBL:BAC78393.1 xref: EMBL:BAC81536.1 xref: EMBL:CAB66748.2 xref: UniProtKB:Q6UXD6 xref: UniProtKB:Q7L4G1 xref: UniProtKB:Q8IZ52 xref: UniProtKB:Q9H0F8 xref: UniProtKB:Q9H618 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013372 ! CHPF_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006549 ! glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity relationship: has_function CCO:F0007847 ! N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008462 ! css2-pin1 physical interaction relationship: transforms_into CCO:B0011218 ! CHSS2_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0011219 ! CHSS2_HUMAN-Phosphothreonine129 [Term] id: CCO:B0006321 name: MTFR1_HUMAN def: "Mitochondrial fission regulator 1" [UniProtKB:Q15390] synonym: "Chondrocyte protein with a poly-proline region" EXACT [UniProtKB:Q15390] xref: EMBL:AAH36116.1 xref: EMBL:AAH43498.1 xref: EMBL:BAA02798.1 xref: EMBL:CAG33191.1 xref: UniProtKB:Q15390 xref: UniProtKB:Q6IB94 xref: UniProtKB:Q86XH5 xref: UniProtKB:Q8IVD7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005132 ! MTFR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008463 ! mtfr1-pin1 physical interaction relationship: transforms_into CCO:B0013030 ! MTFR1_HUMAN-Phosphotyrosine30 relationship: transforms_into CCO:B0013031 ! MTFR1_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0013032 ! MTFR1_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0013033 ! MTFR1_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0013034 ! MTFR1_HUMAN-Phosphoserine290 [Term] id: CCO:B0006322 name: CYTA_HUMAN def: "Cystatin-A" [UniProtKB:P01040] synonym: "Cystatin-AS" EXACT [UniProtKB:P01040] synonym: "Stefin-A" EXACT [UniProtKB:P01040] xref: EMBL:AAH10379.1 xref: EMBL:BAA13609.1 xref: EMBL:BAA87858.1 xref: EMBL:CAA29398.1 xref: UniProtKB:P01040 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004431 ! CSTA_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000170 ! cornified envelope relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008464 ! csta-ptn physical interaction [Term] id: CCO:B0006323 name: PGAM1_HUMAN def: "Phosphoglycerate mutase 1" [UniProtKB:P18669] synonym: "BPG-dependent PGAM 1" EXACT [UniProtKB:P18669] synonym: "EC 3.1.3.13" EXACT [UniProtKB:P18669] synonym: "EC 5.4.2.1" EXACT [UniProtKB:P18669] synonym: "EC 5.4.2.4" EXACT [UniProtKB:P18669] synonym: "PGAM-B" EXACT [UniProtKB:P18669] synonym: "Phosphoglycerate mutase isozyme B" EXACT [UniProtKB:P18669] xref: EMBL:AAA60071.1 xref: EMBL:AAG01990.1 xref: EMBL:AAH10038.1 xref: EMBL:AAH11678.1 xref: EMBL:AAH53356.1 xref: EMBL:AAH66959.1 xref: EMBL:AAH73742.1 xref: UniProtKB:P18669 xref: UniProtKB:Q9BWC0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005302 ! PGAM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008466 ! dctn1-pgam1 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:I0020232 ! arf4l-pgam1 physical interaction relationship: participates_in CCO:I0020399 ! pgam1-g22p1 physical interaction relationship: transforms_into CCO:B0013494 ! PGAM1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0013495 ! PGAM1_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0013496 ! PGAM1_HUMAN-Phosphotyrosine26 relationship: transforms_into CCO:B0013497 ! PGAM1_HUMAN-Phosphoserine118 [Term] id: CCO:B0006324 name: ARL8B_HUMAN def: "ADP-ribosylation factor-like protein 8B" [UniProtKB:Q9NVJ2] synonym: "ADP-ribosylation factor-like protein 10C" EXACT [UniProtKB:Q9NVJ2] synonym: "Novel small G protein indispensable for equal chromosome segregation 1" EXACT [UniProtKB:Q9NVJ2] xref: EMBL:AAH13131.1 xref: EMBL:AAH63125.1 xref: EMBL:BAA91759.1 xref: EMBL:BAD23992.1 xref: EMBL:CAG33545.1 xref: UniProtKB:Q9NVJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004097 ! ARL8B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008467 ! dleu1-arl10c physical interaction relationship: participates_in CCO:I0020251 ! atp5j2-arl10c physical interaction relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0006326 name: PEF1_HUMAN def: "Peflin" [UniProtKB:Q9UBV8] synonym: "PEF protein with a long N-terminal hydrophobic domain" EXACT [UniProtKB:Q9UBV8] synonym: "Penta-EF hand domain-containing protein 1" EXACT [UniProtKB:Q9UBV8] xref: EMBL:AAH02773.1 xref: EMBL:AAH12561.1 xref: EMBL:AAQ89370.1 xref: EMBL:BAA84922.1 xref: EMBL:BAA85163.1 xref: EMBL:BAA91680.1 xref: EMBL:CAG46936.1 xref: UniProtKB:Q9UBV8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005297 ! PEF1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008471 ! dnm2-pef1 physical interaction relationship: participates_in CCO:I0015835 ! pdcd6-pef1 physical interaction [Term] id: CCO:B0006327 name: PPIB_HUMAN def: "Peptidyl-prolyl cis-trans isomerase B precursor" [UniProtKB:P23284] synonym: "Cyclophilin B" EXACT [UniProtKB:P23284] synonym: "CYP-S1" EXACT [UniProtKB:P23284] synonym: "EC 5.2.1.8" EXACT [UniProtKB:P23284] synonym: "PPIase" EXACT [UniProtKB:P23284] synonym: "Rotamase" EXACT [UniProtKB:P23284] synonym: "S-cyclophilin" EXACT [UniProtKB:P23284] synonym: "SCYLP" EXACT [UniProtKB:P23284] xref: EMBL:AAA35733.1 xref: EMBL:AAA36601.1 xref: EMBL:AAA52150.1 xref: EMBL:AAH01125.1 xref: EMBL:AAH08848.1 xref: EMBL:AAH20800.1 xref: EMBL:AAH32138.1 xref: EMBL:AAX44050.1 xref: EMBL:BAF83838.1 xref: EMBL:CAG33110.1 xref: EMBL:EAW77669.1 xref: UniProtKB:A8K534 xref: UniProtKB:P23284 xref: UniProtKB:Q6IBH5 xref: UniProtKB:Q9BVK5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005365 ! PPIB_human relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008472 ! dnm2-ppib physical interaction relationship: participates_in CCO:I0017104 ! traf1-ppib physical interaction [Term] id: CCO:B0006328 name: FBX18_HUMAN def: "F-box only protein 18" [UniProtKB:Q8NFZ0] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q8NFZ0] synonym: "F-box DNA helicase 1" EXACT [UniProtKB:Q8NFZ0] xref: EMBL:AAH12762.2 xref: EMBL:AAH32674.2 xref: EMBL:AAI13378.1 xref: EMBL:AAM73631.1 xref: EMBL:AAP97700.1 xref: EMBL:AAP97705.1 xref: EMBL:BAB55073.1 xref: EMBL:BAB55154.1 xref: EMBL:BAC04535.1 xref: EMBL:CAB61392.1 xref: EMBL:CAI41073.1 xref: UniProtKB:Q5JVB1 xref: UniProtKB:Q7Z4Q6 xref: UniProtKB:Q7Z4R0 xref: UniProtKB:Q8N1P5 xref: UniProtKB:Q8N586 xref: UniProtKB:Q8NFZ0 xref: UniProtKB:Q96E82 xref: UniProtKB:Q96K67 xref: UniProtKB:Q96SW7 xref: UniProtKB:Q9UFB2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004622 ! FBXO18_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008473 ! fbxo18-pim2 physical interaction [Term] id: CCO:B0006329 name: ANKZ1_HUMAN def: "Ankyrin repeat and zinc finger domain-containing protein 1" [UniProtKB:Q9H8Y5] synonym: "Zinc finger protein 744" EXACT [UniProtKB:Q9H8Y5] xref: EMBL:AAH00238.1 xref: EMBL:AAH08948.1 xref: EMBL:ABD65410.1 xref: EMBL:BAA91596.1 xref: EMBL:BAB14462.1 xref: UniProtKB:Q9H8Y5 xref: UniProtKB:Q9NVZ4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004061 ! ANKZF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008474 ! flj10415-aurkb physical interaction relationship: transforms_into CCO:B0010533 ! ANKZ1_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0010534 ! ANKZ1_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0010535 ! ANKZ1_HUMAN-Phosphoserine398 relationship: transforms_into CCO:B0010536 ! ANKZ1_HUMAN-Phosphothreonine607 relationship: transforms_into CCO:B0048157 ! ANKZ1_HUMAN-Phosphoserine675 [Term] id: CCO:B0006330 name: CG025_HUMAN def: "UPF0415 protein C7orf25" [UniProtKB:Q9BPX7] xref: EMBL:AAH00769.1 xref: EMBL:AAH01845.1 xref: EMBL:BAB15019.1 xref: UniProtKB:Q9BPX7 xref: UniProtKB:Q9H779 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004337 ! C7orf25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008476 ! fzr1-c7orf25 physical interaction relationship: transforms_into CCO:B0011193 ! CG025_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0011194 ! CG025_HUMAN-Phosphoserine210 relationship: transforms_into CCO:B0011195 ! CG025_HUMAN-Phosphoserine212 [Term] id: CCO:B0006331 name: GOLM1_HUMAN def: "Golgi membrane protein 1" [UniProtKB:Q8NBJ4] synonym: "Golgi membrane protein GP73" EXACT [UniProtKB:Q8NBJ4] synonym: "Golgi phosphoprotein 2" EXACT [UniProtKB:Q8NBJ4] xref: EMBL:AAF44663.1 xref: EMBL:AAH01740.1 xref: EMBL:AAQ88956.1 xref: EMBL:BAC11685.1 xref: EMBL:CAG33482.1 xref: UniProtKB:Q6IAF4 xref: UniProtKB:Q8NBJ4 xref: UniProtKB:Q9NRB9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004716 ! GOLM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008478 ! golph2-clk1 physical interaction relationship: participates_in CCO:I0019725 ! golph2-fth1 physical interaction relationship: participates_in CCO:I0020013 ! golph2-rpa2 physical interaction relationship: participates_in CCO:I0020326 ! golph2-eif3s1 physical interaction relationship: participates_in CCO:I0020327 ! golph2-surf5 physical interaction relationship: participates_in CCO:I0020569 ! golph2-wdr39 physical interaction [Term] id: CCO:B0006332 name: INPP_HUMAN def: "Inositol polyphosphate 1-phosphatase" [UniProtKB:P49441] synonym: "EC 3.1.3.57" EXACT [UniProtKB:P49441] synonym: "IPP" EXACT [UniProtKB:P49441] synonym: "IPPase" EXACT [UniProtKB:P49441] xref: EMBL:AAA36117.1 xref: EMBL:AAD46766.1 xref: EMBL:AAH15496.1 xref: UniProtKB:P49441 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004899 ! INPP1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0000844 ! inositol-1,4-bisphosphate 1-phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004657 ! lithium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008480 ! inpp1-lig1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0048287 ! INPP_HUMAN-Phosphoserine317 [Term] id: CCO:B0006333 name: TTLL5_HUMAN def: "Tubulin polyglutamylase TTLL5" [UniProtKB:Q6EMB2] synonym: "EC 6.-.-.-" EXACT [UniProtKB:Q6EMB2] synonym: "SRC1 and TIF2-associated modulatory protein" EXACT [UniProtKB:Q6EMB2] synonym: "Tubulin--tyrosine ligase-like protein 5" EXACT [UniProtKB:Q6EMB2] xref: EMBL:AAF23275.2 xref: EMBL:AAP75557.1 xref: EMBL:BAA76842.1 xref: UniProtKB:Q6EMB2 xref: UniProtKB:Q9P1V5 xref: UniProtKB:Q9UPZ4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005843 ! TTLL5_human relationship: has_function CCO:F0001193 ! tubulin-tyrosine ligase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0008481 ! kiaa0998-cdkn1a physical interaction relationship: transforms_into CCO:B0014555 ! TTLL5_HUMAN-Phosphothreonine515 [Term] id: CCO:B0006334 name: AMRP_HUMAN def: "Alpha-2-macroglobulin receptor-associated protein precursor" [UniProtKB:P30533] synonym: "Alpha-2-MRAP" EXACT [UniProtKB:P30533] synonym: "Low density lipoprotein receptor-related protein-associated protein 1" EXACT [UniProtKB:P30533] synonym: "RAP" EXACT [UniProtKB:P30533] xref: EMBL:AAA51553.1 xref: EMBL:AAA87889.1 xref: EMBL:AAC67373.1 xref: EMBL:AAI05075.1 xref: EMBL:AAI12068.1 xref: EMBL:BAD96224.1 xref: EMBL:BAD96247.1 xref: EMBL:CAM21451.1 xref: UniProtKB:P30533 xref: UniProtKB:Q2M310 xref: UniProtKB:Q53HQ3 xref: UniProtKB:Q53HS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004051 ! LRPAP1_human relationship: has_function CCO:F0001227 ! asialoglycoprotein receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008482 ! lrpap1-ppm1g physical interaction relationship: participates_in CCO:I0020054 ! lrpap1-pola2 physical interaction relationship: participates_in CCO:I0020055 ! lrpap1-rtn4 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0006335 name: LRSM1_HUMAN def: "E3 ubiquitin-protein ligase LRSAM1" [UniProtKB:Q6UWE0] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q6UWE0] synonym: "hTAL" EXACT [UniProtKB:Q6UWE0] synonym: "Leucine-rich repeat and sterile alpha motif-containing protein 1" EXACT [UniProtKB:Q6UWE0] synonym: "Tsg101-associated ligase" EXACT [UniProtKB:Q6UWE0] xref: EMBL:AAH09239.1 xref: EMBL:AAQ89189.1 xref: EMBL:BAB71119.1 xref: EMBL:BAB71144.1 xref: EMBL:BAC03703.1 xref: EMBL:CAH72930.1 xref: EMBL:CAH72931.1 xref: UniProtKB:Q5VVV0 xref: UniProtKB:Q6UWE0 xref: UniProtKB:Q8NB40 xref: UniProtKB:Q96GT5 xref: UniProtKB:Q96MX5 xref: UniProtKB:Q96MZ7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004989 ! LRSAM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008483 ! lrsam1-mutyh physical interaction relationship: participates_in CCO:I0015139 ! lrsam1-tsg101 physical interaction relationship: participates_in CCO:I0019097 ! atxn1-lrsam1 physical interaction relationship: participates_in CCO:I0020585 ! lrsam1-myl2 physical interaction relationship: participates_in CCO:I0020586 ! lrsam1-rxrg physical interaction relationship: transforms_into CCO:B0067784 ! LRSM1_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0067785 ! LRSM1_HUMAN-Phosphoserine604 [Term] id: CCO:B0006336 name: NOL12_HUMAN def: "Nucleolar protein 12" [UniProtKB:Q9UGY1] xref: EMBL:AAH02808.1 xref: EMBL:CAB63039.1 xref: EMBL:CAB77148.1 xref: EMBL:CAG30349.1 xref: UniProtKB:Q9UGY1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005204 ! NOL12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008484 ! mgc3731-cdk4 physical interaction relationship: participates_in CCO:I0020070 ! mgc3731-sap18 physical interaction relationship: participates_in CCO:I0020368 ! mgc3731-sod2 physical interaction relationship: transforms_into CCO:B0013204 ! NOL12_HUMAN-Phosphothreonine124 relationship: transforms_into CCO:B0013205 ! NOL12_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0013206 ! NOL12_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0013207 ! NOL12_HUMAN-Phosphothreonine141 [Term] id: CCO:B0006337 name: MYP0_HUMAN def: "Myelin P0 protein precursor" [UniProtKB:P25189] synonym: "MPP" EXACT [UniProtKB:P25189] synonym: "Myelin peripheral protein" EXACT [UniProtKB:P25189] synonym: "Myelin protein zero" EXACT [UniProtKB:P25189] xref: EMBL:AAA18981.1 xref: EMBL:AAA20656.1 xref: EMBL:AAB28708.1 xref: EMBL:AAH06491.1 xref: EMBL:AAP35411.1 xref: EMBL:BAA01395.1 xref: EMBL:BAA03540.1 xref: EMBL:BAG36330.1 xref: EMBL:CAH70270.1 xref: EMBL:EAW52606.1 xref: UniProtKB:P25189 xref: UniProtKB:Q16072 xref: UniProtKB:Q5VTH4 xref: UniProtKB:Q92677 xref: UniProtKB:Q9BR67 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005150 ! MPZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008485 ! mpz-pinx1 physical interaction relationship: transforms_into CCO:B0013070 ! MYP0_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0013071 ! MYP0_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0013072 ! MYP0_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0013073 ! MYP0_HUMAN-Phosphoserine243 [Term] id: CCO:B0006339 name: DEF1_HUMAN def: "Neutrophil defensin 1 precursor" [UniProtKB:P59665] synonym: "Defensin, alpha 1" EXACT [UniProtKB:P59665] synonym: "HNP-1" EXACT [UniProtKB:P59665] synonym: "HP-1" EXACT [UniProtKB:P59665] synonym: "HP1" EXACT [UniProtKB:P59665] xref: EMBL:AAA36382.1 xref: EMBL:AAA52302.1 xref: EMBL:AAA52303.1 xref: EMBL:AAH69423.1 xref: EMBL:CAA36280.1 xref: UniProtKB:P11479 xref: UniProtKB:P59665 xref: UniProtKB:Q14125 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004462 ! DEFA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0008488 ! pfdn1-defa1 physical interaction relationship: transforms_into CCO:B0064721 ! DEF1_HUMAN-Phosphotyrosine85 [Term] id: CCO:B0006340 name: APR_HUMAN def: "Phorbol-12-myristate-13-acetate-induced protein 1" [UniProtKB:Q13794] synonym: "Immediate-early-response protein APR" EXACT [UniProtKB:Q13794] synonym: "NOXA" EXACT [UniProtKB:Q13794] synonym: "PMA-induced protein 1" EXACT [UniProtKB:Q13794] xref: EMBL:AAH13120.1 xref: EMBL:BAA14111.1 xref: UniProtKB:Q13794 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004085 ! PMAIP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0008489 ! pmaip1-ppbp physical interaction relationship: participates_in CCO:I0017889 ! pmaip1-bclw-1 direct interaction relationship: participates_in CCO:I0019505 ! pmaip1-bclw-2 direct interaction relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000674 ! cell structure disassembly during apoptosis [Term] id: CCO:B0006341 name: PO3F3_HUMAN def: "POU domain, class 3, transcription factor 3" [UniProtKB:P20264] synonym: "Brain-1" EXACT [UniProtKB:P20264] synonym: "Brain-specific homeobox/POU domain protein 1" EXACT [UniProtKB:P20264] synonym: "Brn-1 protein" EXACT [UniProtKB:P20264] xref: EMBL:BAA19459.1 xref: UniProtKB:P20264 xref: UniProtKB:P78379 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005353 ! POU3F3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008490 ! pou3f3-ppp1r15a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0006342 name: MLP3B_HUMAN def: "Microtubule-associated proteins 1A/1B light chain 3B precursor" [UniProtKB:Q9GZQ8] synonym: "Autophagy-related protein LC3 B" EXACT [UniProtKB:Q9GZQ8] synonym: "Autophagy-related ubiquitin-like modifier LC3 B" EXACT [UniProtKB:Q9GZQ8] synonym: "MAP1 light chain 3-like protein 2" EXACT [UniProtKB:Q9GZQ8] synonym: "MAP1A/1B light chain 3 B" EXACT [UniProtKB:Q9GZQ8] synonym: "MAP1A/MAP1B LC3 B" EXACT [UniProtKB:Q9GZQ8] synonym: "Microtubule-associated protein 1 light chain 3 beta" EXACT [UniProtKB:Q9GZQ8] xref: EMBL:AAG09686.1 xref: EMBL:AAG23182.1 xref: EMBL:AAH18634.1 xref: EMBL:AAH41874.1 xref: EMBL:AAH67797.1 xref: EMBL:AAM10499.1 xref: EMBL:BAB15169.1 xref: UniProtKB:Q6NW02 xref: UniProtKB:Q9GZQ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005103 ! MAP1LC3B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000358 ! autophagic vacuole relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001127 ! organelle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0008493 ! rad1-map1lc3b physical interaction relationship: participates_in CCO:I0017407 ! atg7-map1lc3b direct interaction relationship: participates_in CCO:I0019762 ! map1lc3b-sqstm1 physical interaction [Term] id: CCO:B0006343 name: NFL_HUMAN def: "Neurofilament light polypeptide" [UniProtKB:P07196] synonym: "68 kDa neurofilament protein" EXACT [UniProtKB:P07196] synonym: "Neurofilament triplet L protein" EXACT [UniProtKB:P07196] synonym: "NF-L" EXACT [UniProtKB:P07196] xref: EMBL:AAD14057.1 xref: EMBL:AAH39237.1 xref: EMBL:AAN74826.1 xref: EMBL:CAA29097.1 xref: UniProtKB:P07196 xref: UniProtKB:Q16154 xref: UniProtKB:Q8IU72 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005188 ! NEFL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008494 ! ran-nefl physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:I0020527 ! cdk5rap2-nefl physical interaction relationship: transforms_into CCO:B0013169 ! NFL_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0013170 ! NFL_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0013171 ! NFL_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0013172 ! NFL_HUMAN-Phosphoserine472 relationship: transforms_into CCO:B0031358 ! NFL_HUMAN-Phosphotyrosine43 relationship: transforms_into CCO:B0031359 ! NFL_HUMAN-Phosphotyrosine424 relationship: transforms_into CCO:B0031360 ! NFL_HUMAN-Phosphotyrosine432 [Term] id: CCO:B0006344 name: NUD10_HUMAN def: "Diphosphoinositol polyphosphate phosphohydrolase 3-alpha" [UniProtKB:Q8NFP7] synonym: "Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha" EXACT [UniProtKB:Q8NFP7] synonym: "DIPP-3-alpha" EXACT [UniProtKB:Q8NFP7] synonym: "DIPP3-alpha" EXACT [UniProtKB:Q8NFP7] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q8NFP7] synonym: "EC 3.6.1.52" EXACT [UniProtKB:Q8NFP7] synonym: "hAps2" EXACT [UniProtKB:Q8NFP7] synonym: "hDIPP3alpha" EXACT [UniProtKB:Q8NFP7] synonym: "Nucleoside diphosphate-linked moiety X motif 10" EXACT [UniProtKB:Q8NFP7] synonym: "Nudix motif 10" EXACT [UniProtKB:Q8NFP7] xref: EMBL:AAH49383.1 xref: EMBL:AAH50700.1 xref: EMBL:AAM64113.1 xref: EMBL:CAI40295.1 xref: UniProtKB:Q86VK1 xref: UniProtKB:Q86VR0 xref: UniProtKB:Q8NFP7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005221 ! NUDT10_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001946 ! diphosphoinositol-polyphosphate diphosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008495 ! rassf1-nudt10 physical interaction [Term] id: CCO:B0006345 name: CATB_HUMAN def: "Cathepsin B precursor" [UniProtKB:P07858] synonym: "APP secretase" EXACT [UniProtKB:P07858] synonym: "APPS" EXACT [UniProtKB:P07858] synonym: "Cathepsin B1" EXACT [UniProtKB:P07858] synonym: "EC 3.4.22.1" EXACT [UniProtKB:P07858] xref: EMBL:AAA52125.1 xref: EMBL:AAA52129.1 xref: EMBL:AAC37547.1 xref: EMBL:AAH10240.1 xref: EMBL:AAH95408.1 xref: UniProtKB:P07858 xref: UniProtKB:Q503A6 xref: UniProtKB:Q96D87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004223 ! CTSB_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000668 ! cathepsin B activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004617 ! kininogen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0008496 ! rgs2-ctsb physical interaction relationship: participates_in CCO:I0019964 ! ctsb-bat3 physical interaction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0006346 name: SCN5A_HUMAN def: "Sodium channel protein type 5 subunit alpha" [UniProtKB:Q14524] synonym: "HH1" EXACT [UniProtKB:Q14524] synonym: "Sodium channel protein cardiac muscle subunit alpha" EXACT [UniProtKB:Q14524] synonym: "Sodium channel protein type V subunit alpha" EXACT [UniProtKB:Q14524] synonym: "Voltage-gated sodium channel subunit alpha Nav1.5" EXACT [UniProtKB:Q14524] xref: EMBL:AAA58644.1 xref: UniProtKB:Q14524 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005573 ! SCN5A_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001516 ! voltage-gated sodium channel activity relationship: has_function CCO:F0001527 ! sodium channel activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000167 ! voltage-gated sodium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008497 ! rgs2-scn5a physical interaction [Term] id: CCO:B0006347 name: XPP1_HUMAN def: "Xaa-Pro aminopeptidase 1" [UniProtKB:Q9NQW7] synonym: "Aminoacylproline aminopeptidase" EXACT [UniProtKB:Q9NQW7] synonym: "Cytosolic aminopeptidase P" EXACT [UniProtKB:Q9NQW7] synonym: "EC 3.4.11.9" EXACT [UniProtKB:Q9NQW7] synonym: "sAmp" EXACT [UniProtKB:Q9NQW7] synonym: "Soluble aminopeptidase P" EXACT [UniProtKB:Q9NQW7] synonym: "X-Pro aminopeptidase 1" EXACT [UniProtKB:Q9NQW7] synonym: "X-prolyl aminopeptidase 1, soluble" EXACT [UniProtKB:Q9NQW7] xref: EMBL:AAF75795.1 xref: EMBL:AAF97866.1 xref: EMBL:AAH05126.1 xref: EMBL:AAH07579.1 xref: EMBL:AAH13417.4 xref: EMBL:BAD97233.1 xref: EMBL:CAA65068.1 xref: EMBL:CAD38640.1 xref: EMBL:CAG33203.1 xref: EMBL:CAI14248.1 xref: UniProtKB:O15250 xref: UniProtKB:Q53EX6 xref: UniProtKB:Q8N3Q0 xref: UniProtKB:Q96D23 xref: UniProtKB:Q9NQW7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005944 ! XPNPEP1_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001785 ! metalloexopeptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001914 ! X-Pro aminopeptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008500 ! rint1-xpnpep1 physical interaction relationship: participates_in CCO:I0020363 ! mapk9-xpnpep1 physical interaction relationship: participates_in CCO:I0020496 ! xpnpep1-pola2 physical interaction [Term] id: CCO:B0006349 name: SCFD1_HUMAN def: "Sec1 family domain-containing protein 1" [UniProtKB:Q8WVM8] synonym: "Sly1p" EXACT [UniProtKB:Q8WVM8] synonym: "Syntaxin-binding protein 1-like 2" EXACT [UniProtKB:Q8WVM8] xref: EMBL:AAC17907.1 xref: EMBL:AAD40381.1 xref: EMBL:AAD48586.1 xref: EMBL:AAG50273.1 xref: EMBL:AAH17734.1 xref: EMBL:AAP97146.1 xref: EMBL:BAA74940.2 xref: UniProtKB:O60754 xref: UniProtKB:O94990 xref: UniProtKB:Q7Z529 xref: UniProtKB:Q8WVM8 xref: UniProtKB:Q9BZI3 xref: UniProtKB:Q9UNL3 xref: UniProtKB:Q9Y6A8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005571 ! SCFD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008503 ! scfd1-ppbp physical interaction relationship: participates_in CCO:I0008817 ! usp22-scfd1 physical interaction relationship: transforms_into CCO:B0013966 ! SCFD1_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0013967 ! SCFD1_HUMAN-Phosphoserine528 relationship: transforms_into CCO:B0070344 ! SCFD1_HUMAN-Phosphoserine303 [Term] id: CCO:B0006350 name: VAMP8_HUMAN def: "Vesicle-associated membrane protein 8" [UniProtKB:Q9BV40] synonym: "EDB" EXACT [UniProtKB:Q9BV40] synonym: "Endobrevin" EXACT [UniProtKB:Q9BV40] synonym: "VAMP-8" EXACT [UniProtKB:Q9BV40] xref: EMBL:AAC08434.1 xref: EMBL:AAH01634.1 xref: EMBL:AAP35346.1 xref: EMBL:AAY24341.1 xref: EMBL:CAG33276.1 xref: UniProtKB:O60625 xref: UniProtKB:Q53SP9 xref: UniProtKB:Q6IB09 xref: UniProtKB:Q9BV40 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005892 ! VAMP8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008504 ! pnn-vamp8 physical interaction [Term] id: CCO:B0006351 name: WBP2_HUMAN def: "WW domain-binding protein 2" [UniProtKB:Q969T9] synonym: "WBP-2" EXACT [UniProtKB:Q969T9] xref: EMBL:AAD10951.1 xref: EMBL:AAH07452.1 xref: EMBL:AAH10616.1 xref: UniProtKB:O95638 xref: UniProtKB:Q969T9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005914 ! WBP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0008505 ! sept3-wbp2 physical interaction relationship: transforms_into CCO:B0014668 ! WBP2_HUMAN-Phosphotyrosine232 [Term] id: CCO:B0006352 name: STRN4_HUMAN def: "Striatin-4" [UniProtKB:Q9NRL3] synonym: "Zinedin" EXACT [UniProtKB:Q9NRL3] xref: EMBL:AAF29527.1 xref: EMBL:AAH04910.2 xref: EMBL:AAH34604.1 xref: UniProtKB:Q8NE53 xref: UniProtKB:Q9NRL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005699 ! STRN4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008507 ! strn4-ppbp physical interaction relationship: participates_in CCO:I0008552 ! strn4-asns physical interaction relationship: participates_in CCO:I0020176 ! strn4-klhdc2 physical interaction relationship: participates_in CCO:I0020461 ! strn4-ak5 physical interaction relationship: participates_in CCO:I0020462 ! strn4-bat1 physical interaction relationship: participates_in CCO:I0020463 ! strn4-cldn12 physical interaction relationship: participates_in CCO:I0020464 ! strn4-gdf9 physical interaction relationship: participates_in CCO:I0020465 ! strn4-nbea physical interaction relationship: participates_in CCO:I0020466 ! strn4-pik4ca physical interaction relationship: participates_in CCO:I0020467 ! strn4-slc25a6 physical interaction relationship: participates_in CCO:I0020468 ! strn4-sprn physical interaction relationship: participates_in CCO:I0020671 ! strn4-dffa physical interaction relationship: participates_in CCO:I0020672 ! strn4-flj23342 physical interaction relationship: participates_in CCO:I0020673 ! strn4-cxorf26 physical interaction relationship: participates_in CCO:I0020674 ! strn4-mif physical interaction relationship: participates_in CCO:I0020675 ! strn4-wnt7a physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0014269 ! STRN4_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0070979 ! STRN4_HUMAN-Phosphoserine276 [Term] id: CCO:B0006353 name: Q9P0U0_HUMAN def: "PC326 protein" [UniProtKB:Q9P0U0] xref: EMBL:AAF67474.1 xref: UniProtKB:Q9H0M1 xref: UniProtKB:Q9P0U0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006055 ! IQWD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008509 ! supt5h-iqwd1 physical interaction [Term] id: CCO:B0006354 name: ADPGK_HUMAN def: "ADP-dependent glucokinase precursor" [UniProtKB:Q9BRR6] synonym: "ADP-GK" EXACT [UniProtKB:Q9BRR6] synonym: "ADPGK" EXACT [UniProtKB:Q9BRR6] synonym: "EC 2.7.1.147" EXACT [UniProtKB:Q9BRR6] synonym: "RbBP-35" EXACT [UniProtKB:Q9BRR6] xref: EMBL:AAH06112.1 xref: EMBL:AAH18074.1 xref: EMBL:AAL31473.1 xref: EMBL:BAB70941.1 xref: EMBL:BAC11699.1 xref: EMBL:CAB66807.1 xref: EMBL:CAG38478.1 xref: UniProtKB:Q49AU7 xref: UniProtKB:Q8NBI1 xref: UniProtKB:Q8WZ90 xref: UniProtKB:Q96NF8 xref: UniProtKB:Q9BRR6 xref: UniProtKB:Q9H0A7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004031 ! ADPGK_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0006010 ! ADP-specific glucokinase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008511 ! tada3l-adpgk physical interaction relationship: participates_in CCO:I0020502 ! adpgk-gdf9 physical interaction [Term] id: CCO:B0006355 name: Q5T9K6_HUMAN def: "Family with sequence similarity 107, member B" [UniProtKB:Q5T9K6] xref: EMBL:CAI12273.1 xref: UniProtKB:Q5T9K6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006000 ! FAM107B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008512 ! tada3l-c10orf45 physical interaction [Term] id: CCO:B0010364 name: 1433B_HUMAN-N-acetylthreonine2 def: "Protein 1433B_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P31946] comment: By similarity xref: UniProtKB:P31946 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005480 ! 1433B_HUMAN [Term] id: CCO:B0010365 name: 1433B_HUMAN-Phosphoserine186 def: "Protein 1433B_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:P31946] comment: By similarity xref: UniProtKB:P31946 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0005480 ! 1433B_HUMAN [Term] id: CCO:B0010366 name: 1433E_HUMAN-N-acetylmethionine1 def: "Protein 1433E_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P62258] xref: UniProtKB:P62258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005488 ! 1433E_HUMAN [Term] id: CCO:B0010367 name: 1433E_HUMAN-Phosphoserine210 def: "Protein 1433E_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:P62258] xref: UniProtKB:P62258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005488 ! 1433E_HUMAN [Term] id: CCO:B0010368 name: 1433F_HUMAN-N-acetylglycine2 def: "Protein 1433F_HUMAN with the residue 2 substituted with N-acetylglycine" [UniProtKB:Q04917] xref: UniProtKB:Q04917 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:B0010369 name: 1433G_HUMAN-N-acetylvaline2 def: "Protein 1433G_HUMAN with the residue 2 substituted with N-acetylvaline" [UniProtKB:P61981] comment: partial; xref: UniProtKB:P61981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005489 ! 1433G_HUMAN [Term] id: CCO:B0010370 name: 1433S_HUMAN-Phosphoserine64 def: "Protein 1433S_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:P31947] comment: By similarity xref: UniProtKB:P31947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001584 ! 1433S_HUMAN [Term] id: CCO:B0010371 name: 1433S_HUMAN-Phosphoserine216 def: "Protein 1433S_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:P31947] comment: By similarity xref: UniProtKB:P31947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001893 ! protein kinase C inhibitor activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001584 ! 1433S_HUMAN [Term] id: CCO:B0010372 name: 1433S_HUMAN-Phosphoserine248 def: "Protein 1433S_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:P31947] xref: UniProtKB:P31947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001584 ! 1433S_HUMAN [Term] id: CCO:B0010373 name: 1433Z_HUMAN-N-acetylmethionine1 def: "Protein 1433Z_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P63104] xref: UniProtKB:P63104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:B0010374 name: 1433Z_HUMAN-Phosphoserine184 def: "Protein 1433Z_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:P63104] comment: By similarity xref: UniProtKB:P63104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:B0010375 name: 1433Z_HUMAN-Phosphothreonine232 def: "Protein 1433Z_HUMAN with the residue 232 substituted with Phosphothreonine" [UniProtKB:P63104] xref: UniProtKB:P63104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:B0010376 name: 2A5D_HUMAN-Phosphoserine598 def: "Protein 2A5D_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q14738] xref: UniProtKB:Q14738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005515 ! 2A5D_HUMAN [Term] id: CCO:B0010377 name: 2AAA_HUMAN-N-acetylalanine2 def: "Protein 2AAA_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P30153] xref: UniProtKB:P30153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001571 ! 2AAA_HUMAN [Term] id: CCO:B0010378 name: 4ET_HUMAN-Phosphoserine78 def: "Protein 4ET_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:Q9NRA8] comment: By similarity xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0010379 name: 4ET_HUMAN-Phosphoserine587 def: "Protein 4ET_HUMAN with the residue 587 substituted with Phosphoserine" [UniProtKB:Q9NRA8] comment: By similarity xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0010380 name: 4F2_HUMAN-Phosphoserine2 def: "Protein 4F2_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P08195] xref: UniProtKB:P08195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005463 ! 4F2_HUMAN [Term] id: CCO:B0010381 name: 4F2_HUMAN-Phosphothreonine5 def: "Protein 4F2_HUMAN with the residue 5 substituted with Phosphothreonine" [UniProtKB:P08195] xref: UniProtKB:P08195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001612 ! calcium:sodium antiporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005808 ! cation binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005463 ! 4F2_HUMAN [Term] id: CCO:B0010382 name: A4_HUMAN-Phosphoserine198 def: "Protein A4_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:P05067] comment: by CK2; xref: UniProtKB:P05067 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005474 ! A4_HUMAN [Term] id: CCO:B0010383 name: A4_HUMAN-Phosphoserine206 def: "Protein A4_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:P05067] comment: by CK1; xref: UniProtKB:P05067 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005474 ! A4_HUMAN [Term] id: CCO:B0010384 name: A4_HUMAN-Phosphothreonine729 def: "Protein A4_HUMAN with the residue 729 substituted with Phosphothreonine" [UniProtKB:P05067] comment: By similarity xref: UniProtKB:P05067 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005474 ! A4_HUMAN [Term] id: CCO:B0010385 name: A4_HUMAN-Phosphoserine730 def: "Protein A4_HUMAN with the residue 730 substituted with Phosphoserine" [UniProtKB:P05067] comment: by APP-kinase I; By similarity xref: UniProtKB:P05067 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005061 ! acetylcholine receptor binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: transformation_of CCO:B0005474 ! A4_HUMAN [Term] id: CCO:B0010386 name: A4_HUMAN-Phosphothreonine743 def: "Protein A4_HUMAN with the residue 743 substituted with Phosphothreonine" [UniProtKB:P05067] comment: by CDK5 and MAPK10; xref: UniProtKB:P05067 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005474 ! A4_HUMAN [Term] id: CCO:B0010387 name: A4_HUMAN-Phosphotyrosine757 def: "Protein A4_HUMAN with the residue 757 substituted with Phosphotyrosine" [UniProtKB:P05067] xref: UniProtKB:P05067 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005474 ! A4_HUMAN [Term] id: CCO:B0010388 name: AAPK1_HUMAN-Phosphothreonine174 def: "Protein AAPK1_HUMAN with the residue 174 substituted with Phosphothreonine" [UniProtKB:Q13131] comment: by STK11; By similarity xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0010389 name: AAPK1_HUMAN-Phosphoserine175 def: "Protein AAPK1_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:Q13131] comment: By similarity xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0010390 name: AAPK1_HUMAN-Phosphoserine499 def: "Protein AAPK1_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:Q13131] comment: By similarity xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0010391 name: AATF_HUMAN-Phosphoserine203 def: "Protein AATF_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q9NY61] xref: UniProtKB:Q9NY61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:B0010392 name: AATF_HUMAN-Phosphoserine316 def: "Protein AATF_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q9NY61] xref: UniProtKB:Q9NY61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:B0010393 name: AATF_HUMAN-Phosphoserine320 def: "Protein AATF_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q9NY61] xref: UniProtKB:Q9NY61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:B0010394 name: AATF_HUMAN-Phosphoserine321 def: "Protein AATF_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q9NY61] xref: UniProtKB:Q9NY61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:B0010395 name: ABI1_HUMAN-Phosphoserine183 def: "Protein ABI1_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q8IZP0] xref: UniProtKB:Q8IZP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:B0010396 name: ABI1_HUMAN-Phosphoserine225 def: "Protein ABI1_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q8IZP0] xref: UniProtKB:Q8IZP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:B0010397 name: ABI1_HUMAN-Phosphotyrosine333 def: "Protein ABI1_HUMAN with the residue 333 substituted with Phosphotyrosine" [UniProtKB:Q8IZP0] xref: UniProtKB:Q8IZP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:B0010398 name: ABL1_HUMAN-Phosphotyrosine185 def: "Protein ABL1_HUMAN with the residue 185 substituted with Phosphotyrosine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010399 name: ABL1_HUMAN-Phosphotyrosine226 def: "Protein ABL1_HUMAN with the residue 226 substituted with Phosphotyrosine" [UniProtKB:P00519] comment: by autocatalysis; xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010400 name: ABL1_HUMAN-Phosphotyrosine253 def: "Protein ABL1_HUMAN with the residue 253 substituted with Phosphotyrosine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010401 name: ABL1_HUMAN-Phosphotyrosine257 def: "Protein ABL1_HUMAN with the residue 257 substituted with Phosphotyrosine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010402 name: ABL1_HUMAN-Phosphotyrosine264 def: "Protein ABL1_HUMAN with the residue 264 substituted with Phosphotyrosine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010403 name: ABL1_HUMAN-Phosphotyrosine393 def: "Protein ABL1_HUMAN with the residue 393 substituted with Phosphotyrosine" [UniProtKB:P00519] comment: by autocatalysis and SRC-type Tyr-kinases; xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010404 name: ABL1_HUMAN-Phosphothreonine394 def: "Protein ABL1_HUMAN with the residue 394 substituted with Phosphothreonine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010405 name: ABL1_HUMAN-Phosphoserine446 def: "Protein ABL1_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:P00519] comment: By similarity xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010406 name: ABL1_HUMAN-Phosphotyrosine469 def: "Protein ABL1_HUMAN with the residue 469 substituted with Phosphotyrosine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010407 name: ABL1_HUMAN-Phosphoserine569 def: "Protein ABL1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010408 name: ABL1_HUMAN-Phosphoserine683 def: "Protein ABL1_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010409 name: ABL1_HUMAN-Phosphoserine805 def: "Protein ABL1_HUMAN with the residue 805 substituted with Phosphoserine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010410 name: ABL1_HUMAN-Phosphoserine809 def: "Protein ABL1_HUMAN with the residue 809 substituted with Phosphoserine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010411 name: ABL1_HUMAN-Phosphoserine949 def: "Protein ABL1_HUMAN with the residue 949 substituted with Phosphoserine" [UniProtKB:P00519] xref: UniProtKB:P00519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001461 ! ABL1_HUMAN [Term] id: CCO:B0010412 name: ABL2_HUMAN-Phosphoserine203 def: "Protein ABL2_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010413 name: ABL2_HUMAN-Phosphotyrosine231 def: "Protein ABL2_HUMAN with the residue 231 substituted with Phosphotyrosine" [UniProtKB:P42684] comment: By similarity xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010414 name: ABL2_HUMAN-Phosphotyrosine272 def: "Protein ABL2_HUMAN with the residue 272 substituted with Phosphotyrosine" [UniProtKB:P42684] comment: by autocatalysis; By similarity xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010415 name: ABL2_HUMAN-Phosphotyrosine299 def: "Protein ABL2_HUMAN with the residue 299 substituted with Phosphotyrosine" [UniProtKB:P42684] comment: By similarity xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010416 name: ABL2_HUMAN-Phosphotyrosine303 def: "Protein ABL2_HUMAN with the residue 303 substituted with Phosphotyrosine" [UniProtKB:P42684] comment: By similarity xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010417 name: ABL2_HUMAN-Phosphotyrosine310 def: "Protein ABL2_HUMAN with the residue 310 substituted with Phosphotyrosine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010418 name: ABL2_HUMAN-Phosphotyrosine439 def: "Protein ABL2_HUMAN with the residue 439 substituted with Phosphotyrosine" [UniProtKB:P42684] comment: by autocatalysis; xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010419 name: ABL2_HUMAN-Phosphothreonine440 def: "Protein ABL2_HUMAN with the residue 440 substituted with Phosphothreonine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005556 ! phosphoinositide 3-kinase regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010420 name: ABL2_HUMAN-Phosphoserine492 def: "Protein ABL2_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:P42684] comment: By similarity xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010421 name: ABL2_HUMAN-Phosphotyrosine515 def: "Protein ABL2_HUMAN with the residue 515 substituted with Phosphotyrosine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010422 name: ABL2_HUMAN-Phosphoserine631 def: "Protein ABL2_HUMAN with the residue 631 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010423 name: ABL2_HUMAN-Phosphoserine783 def: "Protein ABL2_HUMAN with the residue 783 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010424 name: ABL2_HUMAN-Phosphoserine817 def: "Protein ABL2_HUMAN with the residue 817 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010425 name: ABL2_HUMAN-Phosphoserine820 def: "Protein ABL2_HUMAN with the residue 820 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010426 name: ABL2_HUMAN-Phosphoserine936 def: "Protein ABL2_HUMAN with the residue 936 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0010427 name: ACK1_HUMAN-Phosphoserine149 def: "Protein ACK1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q07912] xref: UniProtKB:Q07912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005836 ! ACK1_HUMAN [Term] id: CCO:B0010428 name: ACK1_HUMAN-Phosphotyrosine284 def: "Protein ACK1_HUMAN with the residue 284 substituted with Phosphotyrosine" [UniProtKB:Q07912] comment: by autocatalysis; xref: UniProtKB:Q07912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005836 ! ACK1_HUMAN [Term] id: CCO:B0010429 name: ACK1_HUMAN-Phosphotyrosine518 def: "Protein ACK1_HUMAN with the residue 518 substituted with Phosphotyrosine" [UniProtKB:Q07912] xref: UniProtKB:Q07912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005836 ! ACK1_HUMAN [Term] id: CCO:B0010430 name: ACK1_HUMAN-Phosphotyrosine826 def: "Protein ACK1_HUMAN with the residue 826 substituted with Phosphotyrosine" [UniProtKB:Q07912] xref: UniProtKB:Q07912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005836 ! ACK1_HUMAN [Term] id: CCO:B0010431 name: ACK1_HUMAN-Phosphotyrosine857 def: "Protein ACK1_HUMAN with the residue 857 substituted with Phosphotyrosine" [UniProtKB:Q07912] xref: UniProtKB:Q07912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005836 ! ACK1_HUMAN [Term] id: CCO:B0010432 name: ACK1_HUMAN-Phosphotyrosine858 def: "Protein ACK1_HUMAN with the residue 858 substituted with Phosphotyrosine" [UniProtKB:Q07912] xref: UniProtKB:Q07912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005836 ! ACK1_HUMAN [Term] id: CCO:B0010433 name: ACL6A_HUMAN-Phosphoserine233 def: "Protein ACL6A_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:O96019] xref: UniProtKB:O96019 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001626 ! NuA4 histone acetyltransferase complex relationship: transformation_of CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:B0010434 name: ACSA_HUMAN-Phosphoserine30 def: "Protein ACSA_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q9NR19] xref: UniProtKB:Q9NR19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005570 ! ACSA_HUMAN [Term] id: CCO:B0010435 name: ACSA_HUMAN-Phosphoserine263 def: "Protein ACSA_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q9NR19] comment: By similarity xref: UniProtKB:Q9NR19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005570 ! ACSA_HUMAN [Term] id: CCO:B0010436 name: ACSA_HUMAN-Phosphoserine267 def: "Protein ACSA_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q9NR19] xref: UniProtKB:Q9NR19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000472 ! acetate-CoA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003068 ! AMP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005570 ! ACSA_HUMAN [Term] id: CCO:B0010437 name: ACTA_HUMAN-N-acetylglutamate3 def: "Protein ACTA_HUMAN with the residue 3 substituted with N-acetylglutamate" [UniProtKB:P62736] comment: By similarity xref: UniProtKB:P62736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005810 ! ACTA_HUMAN [Term] id: CCO:B0010438 name: ACTA_HUMAN-Tele-methylhistidine75 def: "Protein ACTA_HUMAN with the residue 75 substituted with Tele-methylhistidine" [UniProtKB:P62736] comment: By similarity xref: UniProtKB:P62736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005810 ! ACTA_HUMAN [Term] id: CCO:B0010439 name: ACTA_HUMAN-Nitrated tyrosine296 def: "Protein ACTA_HUMAN with the residue 296 substituted with Nitrated tyrosine" [UniProtKB:P62736] xref: UniProtKB:P62736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005810 ! ACTA_HUMAN [Term] id: CCO:B0010440 name: ACTB_HUMAN-N-acetylmethionine1 def: "Protein ACTB_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P60709] comment: By similarity xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0001626 ! NuA4 histone acetyltransferase complex relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0010441 name: ACTB_HUMAN-N-acetylaspartate2 def: "Protein ACTB_HUMAN with the residue 2 substituted with N-acetylaspartate" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0010442 name: ACTB_HUMAN-Tele-methylhistidine73 def: "Protein ACTB_HUMAN with the residue 73 substituted with Tele-methylhistidine" [UniProtKB:P60709] comment: By similarity xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0010443 name: ACTB_HUMAN-Phosphotyrosine166 def: "Protein ACTB_HUMAN with the residue 166 substituted with Phosphotyrosine" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0010444 name: ACTB_HUMAN-Phosphotyrosine218 def: "Protein ACTB_HUMAN with the residue 218 substituted with Phosphotyrosine" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0010445 name: ACTB_HUMAN-Phosphotyrosine294 def: "Protein ACTB_HUMAN with the residue 294 substituted with Phosphotyrosine" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0010446 name: ACTN1_HUMAN-Phosphotyrosine12 def: "Protein ACTN1_HUMAN with the residue 12 substituted with Phosphotyrosine" [UniProtKB:P12814] comment: by FAK1; xref: UniProtKB:P12814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:B0010447 name: ACTN1_HUMAN-Phosphothreonine50 def: "Protein ACTN1_HUMAN with the residue 50 substituted with Phosphothreonine" [UniProtKB:P12814] xref: UniProtKB:P12814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:B0010448 name: ACTN1_HUMAN-Phosphoserine140 def: "Protein ACTN1_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P12814] xref: UniProtKB:P12814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:B0010449 name: ACTN4_HUMAN-Phosphotyrosine265 def: "Protein ACTN4_HUMAN with the residue 265 substituted with Phosphotyrosine" [UniProtKB:O43707] xref: UniProtKB:O43707 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001397 ! ACTN4_HUMAN [Term] id: CCO:B0010450 name: ACV1B_HUMAN-Phosphotyrosine380 def: "Protein ACV1B_HUMAN with the residue 380 substituted with Phosphotyrosine" [UniProtKB:P36896] xref: UniProtKB:P36896 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003122 ! activin receptor activity, type I relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003510 ! activin receptor activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007319 ! activin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001597 ! ACV1B_HUMAN [Term] id: CCO:B0010451 name: ADA15_HUMAN-Phosphotyrosine715 def: "Protein ADA15_HUMAN with the residue 715 substituted with Phosphotyrosine" [UniProtKB:Q13444] xref: UniProtKB:Q13444 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005909 ! ADA15_HUMAN [Term] id: CCO:B0010452 name: ADA15_HUMAN-Phosphotyrosine735 def: "Protein ADA15_HUMAN with the residue 735 substituted with Phosphotyrosine" [UniProtKB:Q13444] xref: UniProtKB:Q13444 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005909 ! ADA15_HUMAN [Term] id: CCO:B0010453 name: ADA17_HUMAN-Phosphotyrosine379 def: "Protein ADA17_HUMAN with the residue 379 substituted with Phosphotyrosine" [UniProtKB:P78536] xref: UniProtKB:P78536 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:B0010454 name: ADA17_HUMAN-Phosphoserine382 def: "Protein ADA17_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:P78536] xref: UniProtKB:P78536 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:B0010455 name: ADA17_HUMAN-Phosphothreonine735 def: "Protein ADA17_HUMAN with the residue 735 substituted with Phosphothreonine" [UniProtKB:P78536] comment: by MAPK; xref: UniProtKB:P78536 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:B0010456 name: ADA17_HUMAN-Phosphoserine791 def: "Protein ADA17_HUMAN with the residue 791 substituted with Phosphoserine" [UniProtKB:P78536] xref: UniProtKB:P78536 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:B0010457 name: ADA17_HUMAN-Phosphoserine819 def: "Protein ADA17_HUMAN with the residue 819 substituted with Phosphoserine" [UniProtKB:P78536] xref: UniProtKB:P78536 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:B0010458 name: ADAM9_HUMAN-Phosphoserine758 def: "Protein ADAM9_HUMAN with the residue 758 substituted with Phosphoserine" [UniProtKB:Q13443] xref: UniProtKB:Q13443 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005372 ! ADAM9_HUMAN [Term] id: CCO:B0010459 name: ADAM9_HUMAN-Phosphothreonine761 def: "Protein ADAM9_HUMAN with the residue 761 substituted with Phosphothreonine" [UniProtKB:Q13443] xref: UniProtKB:Q13443 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005372 ! ADAM9_HUMAN [Term] id: CCO:B0010460 name: ADT2_HUMAN-N-acetylthreonine2 def: "Protein ADT2_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P05141] xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0010461 name: ADT2_HUMAN-N6-acetyllysine23 def: "Protein ADT2_HUMAN with the residue 23 substituted with N6-acetyllysine" [UniProtKB:P05141] comment: By similarity xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0010462 name: ADT2_HUMAN-Phosphoserine42 def: "Protein ADT2_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:P05141] comment: By similarity xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002678 ! adenine transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0010463 name: ADT2_HUMAN-N6-acetyllysine92 def: "Protein ADT2_HUMAN with the residue 92 substituted with N6-acetyllysine" [UniProtKB:P05141] comment: By similarity xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0010464 name: ADT2_HUMAN-N6-acetyllysine163 def: "Protein ADT2_HUMAN with the residue 163 substituted with N6-acetyllysine" [UniProtKB:P05141] comment: By similarity xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0010465 name: ADT2_HUMAN-N6-acetyllysine166 def: "Protein ADT2_HUMAN with the residue 166 substituted with N6-acetyllysine" [UniProtKB:P05141] comment: By similarity xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0010466 name: ADT2_HUMAN-N6-acetyllysine199 def: "Protein ADT2_HUMAN with the residue 199 substituted with N6-acetyllysine" [UniProtKB:P05141] comment: By similarity xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0010467 name: AF1L2_HUMAN-Phosphothreonine345 def: "Protein AF1L2_HUMAN with the residue 345 substituted with Phosphothreonine" [UniProtKB:Q8N4X5] comment: By similarity xref: UniProtKB:Q8N4X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004383 ! protein tyrosine kinase activator activity relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001964 ! AF1L2_HUMAN [Term] id: CCO:B0010468 name: AF1L2_HUMAN-Phosphotyrosine413 def: "Protein AF1L2_HUMAN with the residue 413 substituted with Phosphotyrosine" [UniProtKB:Q8N4X5] xref: UniProtKB:Q8N4X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001964 ! AF1L2_HUMAN [Term] id: CCO:B0010469 name: AF1L2_HUMAN-Phosphotyrosine668 def: "Protein AF1L2_HUMAN with the residue 668 substituted with Phosphotyrosine" [UniProtKB:Q8N4X5] xref: UniProtKB:Q8N4X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001964 ! AF1L2_HUMAN [Term] id: CCO:B0010470 name: AF1L2_HUMAN-Phosphothreonine669 def: "Protein AF1L2_HUMAN with the residue 669 substituted with Phosphothreonine" [UniProtKB:Q8N4X5] xref: UniProtKB:Q8N4X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001964 ! AF1L2_HUMAN [Term] id: CCO:B0010471 name: AFAD_HUMAN-Phosphoserine541 def: "Protein AFAD_HUMAN with the residue 541 substituted with Phosphoserine" [UniProtKB:P55196] comment: By similarity xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010472 name: AFAD_HUMAN-Phosphoserine1090 def: "Protein AFAD_HUMAN with the residue 1090 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010473 name: AFAD_HUMAN-Phosphoserine1155 def: "Protein AFAD_HUMAN with the residue 1155 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010474 name: AFAD_HUMAN-Phosphoserine1156 def: "Protein AFAD_HUMAN with the residue 1156 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010475 name: AFAD_HUMAN-Phosphoserine1165 def: "Protein AFAD_HUMAN with the residue 1165 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010476 name: AFAD_HUMAN-Phosphoserine1184 def: "Protein AFAD_HUMAN with the residue 1184 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010477 name: AFAD_HUMAN-Phosphoserine1258 def: "Protein AFAD_HUMAN with the residue 1258 substituted with Phosphoserine" [UniProtKB:P55196] comment: By similarity xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010478 name: AFAD_HUMAN-Phosphothreonine1313 def: "Protein AFAD_HUMAN with the residue 1313 substituted with Phosphothreonine" [UniProtKB:P55196] comment: By similarity xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010479 name: AFAD_HUMAN-Phosphothreonine1317 def: "Protein AFAD_HUMAN with the residue 1317 substituted with Phosphothreonine" [UniProtKB:P55196] comment: By similarity xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010480 name: AFAD_HUMAN-Phosphoserine1681 def: "Protein AFAD_HUMAN with the residue 1681 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0010481 name: AIP_HUMAN-Phosphotyrosine248 def: "Protein AIP_HUMAN with the residue 248 substituted with Phosphotyrosine" [UniProtKB:O00170] xref: UniProtKB:O00170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005380 ! AIP_HUMAN [Term] id: CCO:B0010482 name: AKAP8_HUMAN-Phosphoserine112 def: "Protein AKAP8_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:O43823] xref: UniProtKB:O43823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001399 ! AKAP8_HUMAN [Term] id: CCO:B0010483 name: AKAP8_HUMAN-Phosphoserine323 def: "Protein AKAP8_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:O43823] xref: UniProtKB:O43823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001399 ! AKAP8_HUMAN [Term] id: CCO:B0010484 name: AKAP8_HUMAN-Phosphoserine328 def: "Protein AKAP8_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:O43823] xref: UniProtKB:O43823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001399 ! AKAP8_HUMAN [Term] id: CCO:B0010485 name: AKAP8_HUMAN-Phosphoserine339 def: "Protein AKAP8_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:O43823] xref: UniProtKB:O43823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000190 ! female pronucleus relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0001399 ! AKAP8_HUMAN [Term] id: CCO:B0010486 name: AKAP9_HUMAN-Phosphoserine3869 def: "Protein AKAP9_HUMAN with the residue 3869 substituted with Phosphoserine" [UniProtKB:Q99996] xref: UniProtKB:Q99996 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0005588 ! AKAP9_HUMAN [Term] id: CCO:B0010487 name: AKT1_HUMAN-Phosphoserine124 def: "Protein AKT1_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:P31749] xref: UniProtKB:P31749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:B0010488 name: AKT1_HUMAN-Phosphoserine126 def: "Protein AKT1_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:P31749] xref: UniProtKB:P31749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:B0010489 name: AKT1_HUMAN-Phosphoserine129 def: "Protein AKT1_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:P31749] xref: UniProtKB:P31749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:B0010490 name: AKT1_HUMAN-Phosphothreonine308 def: "Protein AKT1_HUMAN with the residue 308 substituted with Phosphothreonine" [UniProtKB:P31749] comment: by PDPK1; xref: UniProtKB:P31749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:B0010491 name: AKT1_HUMAN-Phosphoserine473 def: "Protein AKT1_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:P31749] xref: UniProtKB:P31749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:B0010492 name: AKT1_HUMAN-Phosphotyrosine474 def: "Protein AKT1_HUMAN with the residue 474 substituted with Phosphotyrosine" [UniProtKB:P31749] xref: UniProtKB:P31749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:B0010493 name: AKT2_HUMAN-Phosphothreonine309 def: "Protein AKT2_HUMAN with the residue 309 substituted with Phosphothreonine" [UniProtKB:P31751] comment: by PDPK1; xref: UniProtKB:P31751 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005910 ! AKT2_HUMAN [Term] id: CCO:B0010494 name: AKT2_HUMAN-Phosphoserine474 def: "Protein AKT2_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:P31751] xref: UniProtKB:P31751 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005910 ! AKT2_HUMAN [Term] id: CCO:B0010495 name: AKT3_HUMAN-Phosphoserine120 def: "Protein AKT3_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:Q9Y243] xref: UniProtKB:Q9Y243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005911 ! AKT3_HUMAN [Term] id: CCO:B0010496 name: AKT3_HUMAN-Phosphoserine123 def: "Protein AKT3_HUMAN with the residue 123 substituted with Phosphoserine" [UniProtKB:Q9Y243] xref: UniProtKB:Q9Y243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005911 ! AKT3_HUMAN [Term] id: CCO:B0010497 name: AKT3_HUMAN-Phosphothreonine305 def: "Protein AKT3_HUMAN with the residue 305 substituted with Phosphothreonine" [UniProtKB:Q9Y243] comment: by PDPK1; xref: UniProtKB:Q9Y243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005911 ! AKT3_HUMAN [Term] id: CCO:B0010498 name: AKT3_HUMAN-Phosphoserine472 def: "Protein AKT3_HUMAN with the residue 472 substituted with Phosphoserine" [UniProtKB:Q9Y243] comment: By similarity xref: UniProtKB:Q9Y243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005911 ! AKT3_HUMAN [Term] id: CCO:B0010499 name: ALK_HUMAN-Phosphoserine211 def: "Protein ALK_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010500 name: ALK_HUMAN-Phosphotyrosine1078 def: "Protein ALK_HUMAN with the residue 1078 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010501 name: ALK_HUMAN-Phosphotyrosine1092 def: "Protein ALK_HUMAN with the residue 1092 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010502 name: ALK_HUMAN-Phosphotyrosine1096 def: "Protein ALK_HUMAN with the residue 1096 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010503 name: ALK_HUMAN-Phosphotyrosine1131 def: "Protein ALK_HUMAN with the residue 1131 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010504 name: ALK_HUMAN-Phosphotyrosine1278 def: "Protein ALK_HUMAN with the residue 1278 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010505 name: ALK_HUMAN-Phosphotyrosine1282 def: "Protein ALK_HUMAN with the residue 1282 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] comment: by autocatalysis; xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010506 name: ALK_HUMAN-Phosphotyrosine1507 def: "Protein ALK_HUMAN with the residue 1507 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010507 name: ALK_HUMAN-Phosphotyrosine1584 def: "Protein ALK_HUMAN with the residue 1584 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010508 name: ALK_HUMAN-Phosphotyrosine1604 def: "Protein ALK_HUMAN with the residue 1604 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0010509 name: AN32A_HUMAN-Phosphoserine158 def: "Protein AN32A_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:P39687] xref: UniProtKB:P39687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0006073 ! AN32A_HUMAN [Term] id: CCO:B0010521 name: ANC2_HUMAN-Phosphoserine218 def: "Protein ANC2_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q9UJX6] xref: UniProtKB:Q9UJX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: transformation_of CCO:B0002216 ! ANC2_HUMAN [Term] id: CCO:B0010522 name: ANC2_HUMAN-Phosphoserine314 def: "Protein ANC2_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:Q9UJX6] xref: UniProtKB:Q9UJX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002216 ! ANC2_HUMAN [Term] id: CCO:B0010523 name: ANC2_HUMAN-Phosphoserine534 def: "Protein ANC2_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:Q9UJX6] xref: UniProtKB:Q9UJX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002216 ! ANC2_HUMAN [Term] id: CCO:B0010528 name: ANGI_HUMAN-Pyrrolidone carboxylic acid25 def: "Protein ANGI_HUMAN with the residue 25 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P03950] xref: UniProtKB:P03950 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000919 ! pancreatic ribonuclease activity relationship: has_function CCO:F0000934 ! ribonuclease activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_function CCO:F0005639 ! peptide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000228 ! basal lamina relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001440 ! angiogenin-PRI complex relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0006220 ! ANGI_HUMAN [Term] id: CCO:B0010529 name: ANKS3_HUMAN-Phosphoserine2 def: "Protein ANKS3_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q6ZW76] xref: UniProtKB:Q6ZW76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005965 ! ANKS3_HUMAN [Term] id: CCO:B0010530 name: ANKS3_HUMAN-Phosphoserine5 def: "Protein ANKS3_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:Q6ZW76] xref: UniProtKB:Q6ZW76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005965 ! ANKS3_HUMAN [Term] id: CCO:B0010531 name: ANKS3_HUMAN-Phosphoserine9 def: "Protein ANKS3_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:Q6ZW76] xref: UniProtKB:Q6ZW76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005965 ! ANKS3_HUMAN [Term] id: CCO:B0010532 name: ANKS3_HUMAN-Phosphoserine320 def: "Protein ANKS3_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q6ZW76] xref: UniProtKB:Q6ZW76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005965 ! ANKS3_HUMAN [Term] id: CCO:B0010533 name: ANKZ1_HUMAN-Phosphoserine258 def: "Protein ANKZ1_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q9H8Y5] xref: UniProtKB:Q9H8Y5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006329 ! ANKZ1_HUMAN [Term] id: CCO:B0010534 name: ANKZ1_HUMAN-Phosphoserine361 def: "Protein ANKZ1_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9H8Y5] xref: UniProtKB:Q9H8Y5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006329 ! ANKZ1_HUMAN [Term] id: CCO:B0010535 name: ANKZ1_HUMAN-Phosphoserine398 def: "Protein ANKZ1_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:Q9H8Y5] xref: UniProtKB:Q9H8Y5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0006329 ! ANKZ1_HUMAN [Term] id: CCO:B0010536 name: ANKZ1_HUMAN-Phosphothreonine607 def: "Protein ANKZ1_HUMAN with the residue 607 substituted with Phosphothreonine" [UniProtKB:Q9H8Y5] xref: UniProtKB:Q9H8Y5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006329 ! ANKZ1_HUMAN [Term] id: CCO:B0010537 name: ANLN_HUMAN-Phosphoserine99 def: "Protein ANLN_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010538 name: ANLN_HUMAN-Phosphoserine182 def: "Protein ANLN_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010539 name: ANLN_HUMAN-Phosphothreonine194 def: "Protein ANLN_HUMAN with the residue 194 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010540 name: ANLN_HUMAN-Phosphothreonine320 def: "Protein ANLN_HUMAN with the residue 320 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010541 name: ANLN_HUMAN-Phosphoserine323 def: "Protein ANLN_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010542 name: ANLN_HUMAN-Phosphoserine362 def: "Protein ANLN_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010543 name: ANLN_HUMAN-Phosphothreonine368 def: "Protein ANLN_HUMAN with the residue 368 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010544 name: ANLN_HUMAN-Phosphothreonine401 def: "Protein ANLN_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010545 name: ANLN_HUMAN-Phosphoserine449 def: "Protein ANLN_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010546 name: ANLN_HUMAN-Phosphoserine485 def: "Protein ANLN_HUMAN with the residue 485 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010547 name: ANLN_HUMAN-Phosphothreonine515 def: "Protein ANLN_HUMAN with the residue 515 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] comment: By similarity xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010548 name: ANLN_HUMAN-Phosphoserine637 def: "Protein ANLN_HUMAN with the residue 637 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010549 name: ANLN_HUMAN-Phosphoserine927 def: "Protein ANLN_HUMAN with the residue 927 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0010550 name: ANXA1_HUMAN-N-acetylalanine2 def: "Protein ANXA1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P04083] xref: UniProtKB:P04083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001479 ! ANXA1_HUMAN [Term] id: CCO:B0010551 name: ANXA1_HUMAN-Phosphoserine5 def: "Protein ANXA1_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:P04083] comment: by TRPM7; xref: UniProtKB:P04083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001479 ! ANXA1_HUMAN [Term] id: CCO:B0010552 name: ANXA1_HUMAN-Phosphotyrosine21 def: "Protein ANXA1_HUMAN with the residue 21 substituted with Phosphotyrosine" [UniProtKB:P04083] comment: by EGFR; xref: UniProtKB:P04083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001479 ! ANXA1_HUMAN [Term] id: CCO:B0010553 name: ANXA1_HUMAN-Phosphothreonine24 def: "Protein ANXA1_HUMAN with the residue 24 substituted with Phosphothreonine" [UniProtKB:P04083] xref: UniProtKB:P04083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001479 ! ANXA1_HUMAN [Term] id: CCO:B0010554 name: ANXA1_HUMAN-Phosphoserine27 def: "Protein ANXA1_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P04083] comment: by PKC; xref: UniProtKB:P04083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001479 ! ANXA1_HUMAN [Term] id: CCO:B0010555 name: ANXA1_HUMAN-Phosphotyrosine207 def: "Protein ANXA1_HUMAN with the residue 207 substituted with Phosphotyrosine" [UniProtKB:P04083] xref: UniProtKB:P04083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001479 ! ANXA1_HUMAN [Term] id: CCO:B0010556 name: ANXA2_HUMAN-N-acetylserine2 def: "Protein ANXA2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001215 ! phospholipase inhibitor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0010557 name: ANXA2_HUMAN-Phosphoserine18 def: "Protein ANXA2_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0010558 name: ANXA2_HUMAN-Phosphothreonine19 def: "Protein ANXA2_HUMAN with the residue 19 substituted with Phosphothreonine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0010559 name: ANXA2_HUMAN-Phosphotyrosine24 def: "Protein ANXA2_HUMAN with the residue 24 substituted with Phosphotyrosine" [UniProtKB:P07355] comment: by SRC; xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0010560 name: ANXA2_HUMAN-Phosphoserine26 def: "Protein ANXA2_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:P07355] comment: by PKC; xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0010561 name: ANXA2_HUMAN-Phosphotyrosine30 def: "Protein ANXA2_HUMAN with the residue 30 substituted with Phosphotyrosine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0010562 name: ANXA6_HUMAN-N-acetylalanine2 def: "Protein ANXA6_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P08133] xref: UniProtKB:P08133 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005731 ! ANXA6_HUMAN [Term] id: CCO:B0010563 name: AP2A_HUMAN-Phosphoserine239 def: "Protein AP2A_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:P05549] comment: by PKA; xref: UniProtKB:P05549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:B0010564 name: AP2B1_HUMAN-Phosphotyrosine737 def: "Protein AP2B1_HUMAN with the residue 737 substituted with Phosphotyrosine" [UniProtKB:P63010] xref: UniProtKB:P63010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005197 ! AP2B1_HUMAN [Term] id: CCO:B0010565 name: AP2B_HUMAN-Phosphoserine258 def: "Protein AP2B_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q92481] comment: by PKA; By similarity xref: UniProtKB:Q92481 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005680 ! AP2B_HUMAN [Term] id: CCO:B0010566 name: AP2C_HUMAN-Phosphoserine252 def: "Protein AP2C_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:Q92754] comment: by PKA; By similarity xref: UniProtKB:Q92754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005377 ! AP2C_HUMAN [Term] id: CCO:B0010567 name: APC_HUMAN-Phosphoserine1038 def: "Protein APC_HUMAN with the residue 1038 substituted with Phosphoserine" [UniProtKB:P25054] comment: By similarity xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0002008 ! protein kinase CK2 regulator activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000783 ! lateral plasma membrane relationship: located_in CCO:C0001067 ! beta-catenin destruction complex relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010568 name: APC_HUMAN-Phosphoserine1180 def: "Protein APC_HUMAN with the residue 1180 substituted with Phosphoserine" [UniProtKB:P25054] comment: By similarity xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010569 name: APC_HUMAN-Phosphoserine1371 def: "Protein APC_HUMAN with the residue 1371 substituted with Phosphoserine" [UniProtKB:P25054] comment: By similarity xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010570 name: APC_HUMAN-Phosphothreonine1697 def: "Protein APC_HUMAN with the residue 1697 substituted with Phosphothreonine" [UniProtKB:P25054] comment: By similarity xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010571 name: APC_HUMAN-Phosphoserine1861 def: "Protein APC_HUMAN with the residue 1861 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010572 name: APC_HUMAN-Phosphoserine1863 def: "Protein APC_HUMAN with the residue 1863 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010573 name: APC_HUMAN-Phosphoserine1864 def: "Protein APC_HUMAN with the residue 1864 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010574 name: APC_HUMAN-Phosphoserine2283 def: "Protein APC_HUMAN with the residue 2283 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010575 name: APC_HUMAN-Phosphoserine2398 def: "Protein APC_HUMAN with the residue 2398 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010576 name: APC_HUMAN-Phosphoserine2674 def: "Protein APC_HUMAN with the residue 2674 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010577 name: APC_HUMAN-Phosphoserine2710 def: "Protein APC_HUMAN with the residue 2710 substituted with Phosphoserine" [UniProtKB:P25054] comment: By similarity xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0010585 name: ARAF_HUMAN-Phosphoserine257 def: "Protein ARAF_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:P10398] xref: UniProtKB:P10398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:B0010586 name: ARAF_HUMAN-Phosphoserine582 def: "Protein ARAF_HUMAN with the residue 582 substituted with Phosphoserine" [UniProtKB:P10398] xref: UniProtKB:P10398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:B0010587 name: ARD1A_HUMAN-Phosphoserine182 def: "Protein ARD1A_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:P41227] xref: UniProtKB:P41227 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005243 ! ARD1A_HUMAN [Term] id: CCO:B0010588 name: ARD1A_HUMAN-Phosphoserine186 def: "Protein ARD1A_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:P41227] xref: UniProtKB:P41227 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000978 ! peptide alpha-N-acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005784 ! ribosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005243 ! ARD1A_HUMAN [Term] id: CCO:B0010589 name: ARFG1_HUMAN-Phosphothreonine135 def: "Protein ARFG1_HUMAN with the residue 135 substituted with Phosphothreonine" [UniProtKB:Q8N6T3] xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0010590 name: ARFG1_HUMAN-Phosphothreonine189 def: "Protein ARFG1_HUMAN with the residue 189 substituted with Phosphothreonine" [UniProtKB:Q8N6T3] xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0010591 name: ARFG1_HUMAN-Phosphoserine246 def: "Protein ARFG1_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q8N6T3] xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0010592 name: ARFG1_HUMAN-Phosphoserine343 def: "Protein ARFG1_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:Q8N6T3] comment: By similarity xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0010593 name: ARFG1_HUMAN-Phosphoserine345 def: "Protein ARFG1_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q8N6T3] comment: By similarity xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0010594 name: ARFG1_HUMAN-Phosphoserine348 def: "Protein ARFG1_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:Q8N6T3] comment: By similarity xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0010595 name: ARFG1_HUMAN-Phosphoserine361 def: "Protein ARFG1_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q8N6T3] comment: By similarity xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0010596 name: ARI1A_HUMAN-Phosphoserine363 def: "Protein ARI1A_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:O14497] xref: UniProtKB:O14497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:B0010597 name: ARI1A_HUMAN-Phosphoserine604 def: "Protein ARI1A_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:O14497] xref: UniProtKB:O14497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:B0010598 name: ARI1A_HUMAN-Phosphoserine696 def: "Protein ARI1A_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:O14497] xref: UniProtKB:O14497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:B0010599 name: ARI1A_HUMAN-Phosphoserine772 def: "Protein ARI1A_HUMAN with the residue 772 substituted with Phosphoserine" [UniProtKB:O14497] xref: UniProtKB:O14497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:B0010600 name: ARI1A_HUMAN-Phosphoserine1755 def: "Protein ARI1A_HUMAN with the residue 1755 substituted with Phosphoserine" [UniProtKB:O14497] xref: UniProtKB:O14497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: transformation_of CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:B0010601 name: ARI2_HUMAN-Phosphoserine353 def: "Protein ARI2_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:O95376] xref: UniProtKB:O95376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005288 ! ARI2_HUMAN [Term] id: CCO:B0010602 name: ARI4A_HUMAN-Phosphoserine1109 def: "Protein ARI4A_HUMAN with the residue 1109 substituted with Phosphoserine" [UniProtKB:P29374] xref: UniProtKB:P29374 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005693 ! ARI4A_HUMAN [Term] id: CCO:B0010603 name: ARL8B_HUMAN-N-acetylmethionine1 def: "Protein ARL8B_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q9NVJ2] xref: UniProtKB:Q9NVJ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004046 ! GDP binding relationship: has_function CCO:F0005781 ! alpha-tubulin binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001017 ! midbody relationship: located_in CCO:C0001340 ! late endosome membrane relationship: located_in CCO:C0002011 ! spindle midzone relationship: transformation_of CCO:B0006324 ! ARL8B_HUMAN [Term] id: CCO:B0010604 name: ARP8_HUMAN-Phosphoserine132 def: "Protein ARP8_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q9H981] xref: UniProtKB:Q9H981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0006058 ! ARP8_HUMAN [Term] id: CCO:B0010605 name: ARSE_HUMAN-3-oxoalanine (Cys)86 def: "Protein ARSE_HUMAN with the residue 86 substituted with 3-oxoalanine (Cys)" [UniProtKB:P51690] comment: By similarity xref: UniProtKB:P51690 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006258 ! ARSE_HUMAN [Term] id: CCO:B0010606 name: ASCC2_HUMAN-Phosphoserine713 def: "Protein ASCC2_HUMAN with the residue 713 substituted with Phosphoserine" [UniProtKB:Q9H1I8] xref: UniProtKB:Q9H1I8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:B0010607 name: ASPM_HUMAN-Phosphoserine14 def: "Protein ASPM_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010608 name: ASPM_HUMAN-Phosphoserine35 def: "Protein ASPM_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010609 name: ASPM_HUMAN-Phosphoserine222 def: "Protein ASPM_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010610 name: ASPM_HUMAN-Phosphoserine225 def: "Protein ASPM_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010611 name: ASPM_HUMAN-Phosphoserine263 def: "Protein ASPM_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010612 name: ASPM_HUMAN-Phosphoserine267 def: "Protein ASPM_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010613 name: ASPM_HUMAN-Phosphoserine270 def: "Protein ASPM_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010614 name: ASPM_HUMAN-Phosphoserine280 def: "Protein ASPM_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010615 name: ASPM_HUMAN-Phosphoserine283 def: "Protein ASPM_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010616 name: ASPM_HUMAN-Phosphoserine348 def: "Protein ASPM_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010617 name: ASPM_HUMAN-Phosphoserine367 def: "Protein ASPM_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010618 name: ASPM_HUMAN-Phosphoserine370 def: "Protein ASPM_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010619 name: ASPM_HUMAN-Phosphoserine392 def: "Protein ASPM_HUMAN with the residue 392 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010620 name: ASPM_HUMAN-Phosphoserine425 def: "Protein ASPM_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010621 name: ASPM_HUMAN-Phosphoserine463 def: "Protein ASPM_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010622 name: ASPM_HUMAN-Phosphothreonine563 def: "Protein ASPM_HUMAN with the residue 563 substituted with Phosphothreonine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010623 name: ASPM_HUMAN-Phosphoserine605 def: "Protein ASPM_HUMAN with the residue 605 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010624 name: ASPM_HUMAN-Phosphothreonine647 def: "Protein ASPM_HUMAN with the residue 647 substituted with Phosphothreonine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010625 name: ASPM_HUMAN-Phosphoserine1103 def: "Protein ASPM_HUMAN with the residue 1103 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010626 name: ASPM_HUMAN-Phosphoserine2429 def: "Protein ASPM_HUMAN with the residue 2429 substituted with Phosphoserine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010627 name: ASPM_HUMAN-Phosphothreonine3435 def: "Protein ASPM_HUMAN with the residue 3435 substituted with Phosphothreonine" [UniProtKB:Q8IZT6] xref: UniProtKB:Q8IZT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001956 ! ASPM_HUMAN [Term] id: CCO:B0010628 name: ASPP1_HUMAN-Phosphoserine332 def: "Protein ASPP1_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:Q96KQ4] comment: By similarity xref: UniProtKB:Q96KQ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002046 ! ASPP1_HUMAN [Term] id: CCO:B0010629 name: ASPP1_HUMAN-Phosphoserine335 def: "Protein ASPP1_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q96KQ4] comment: By similarity xref: UniProtKB:Q96KQ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002046 ! ASPP1_HUMAN [Term] id: CCO:B0010630 name: ASPP1_HUMAN-Phosphoserine671 def: "Protein ASPP1_HUMAN with the residue 671 substituted with Phosphoserine" [UniProtKB:Q96KQ4] comment: By similarity xref: UniProtKB:Q96KQ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002046 ! ASPP1_HUMAN [Term] id: CCO:B0010631 name: ASPP2_HUMAN-Phosphoserine480 def: "Protein ASPP2_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:Q13625] xref: UniProtKB:Q13625 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001764 ! ASPP2_HUMAN [Term] id: CCO:B0010632 name: ASPP2_HUMAN-Phosphoserine698 def: "Protein ASPP2_HUMAN with the residue 698 substituted with Phosphoserine" [UniProtKB:Q13625] xref: UniProtKB:Q13625 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001764 ! ASPP2_HUMAN [Term] id: CCO:B0010633 name: AT1A1_HUMAN-Phosphotyrosine10 def: "Protein AT1A1_HUMAN with the residue 10 substituted with Phosphotyrosine" [UniProtKB:P05023] comment: By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010634 name: AT1A1_HUMAN-Phosphoserine16 def: "Protein AT1A1_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:P05023] comment: by PKC; By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010635 name: AT1A1_HUMAN-Phosphoserine47 def: "Protein AT1A1_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:P05023] comment: By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010636 name: AT1A1_HUMAN-Phosphoserine217 def: "Protein AT1A1_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:P05023] comment: By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010637 name: AT1A1_HUMAN-Phosphothreonine219 def: "Protein AT1A1_HUMAN with the residue 219 substituted with Phosphothreonine" [UniProtKB:P05023] comment: By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001603 ! sodium:potassium-exchanging ATPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002558 ! monovalent inorganic cation transmembrane transporter activity relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000447 ! sodium:potassium-exchanging ATPase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010638 name: AT1A1_HUMAN-Phosphoserine228 def: "Protein AT1A1_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:P05023] comment: By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010639 name: AT1A1_HUMAN-Phosphoserine452 def: "Protein AT1A1_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:P05023] comment: By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010640 name: AT1A1_HUMAN-Phosphoserine943 def: "Protein AT1A1_HUMAN with the residue 943 substituted with Phosphoserine" [UniProtKB:P05023] comment: by PKA; By similarity xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0010641 name: AT2A2_HUMAN-Phosphothreonine537 def: "Protein AT2A2_HUMAN with the residue 537 substituted with Phosphothreonine" [UniProtKB:P16615] comment: By similarity xref: UniProtKB:P16615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001602 ! calcium-transporting ATPase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007316 ! S100 alpha binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000802 ! sarcoplasmic reticulum relationship: located_in CCO:C0001507 ! sarcoplasmic reticulum membrane relationship: transformation_of CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:B0010642 name: AT2A2_HUMAN-Phosphoserine663 def: "Protein AT2A2_HUMAN with the residue 663 substituted with Phosphoserine" [UniProtKB:P16615] xref: UniProtKB:P16615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:B0010643 name: ATF7_HUMAN-Phosphothreonine51 def: "Protein ATF7_HUMAN with the residue 51 substituted with Phosphothreonine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010644 name: ATF7_HUMAN-Phosphothreonine53 def: "Protein ATF7_HUMAN with the residue 53 substituted with Phosphothreonine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010645 name: ATF7_HUMAN-Phosphoserine111 def: "Protein ATF7_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010646 name: ATF7_HUMAN-Phosphothreonine112 def: "Protein ATF7_HUMAN with the residue 112 substituted with Phosphothreonine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010647 name: ATF7_HUMAN-Phosphoserine127 def: "Protein ATF7_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010648 name: ATF7_HUMAN-Phosphoserine128 def: "Protein ATF7_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010649 name: ATF7_HUMAN-Phosphoserine132 def: "Protein ATF7_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010650 name: ATF7_HUMAN-Phosphoserine135 def: "Protein ATF7_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010651 name: ATF7_HUMAN-Phosphoserine136 def: "Protein ATF7_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010652 name: ATF7_HUMAN-Phosphoserine139 def: "Protein ATF7_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0010653 name: ATM_HUMAN-Phosphothreonine72 def: "Protein ATM_HUMAN with the residue 72 substituted with Phosphothreonine" [UniProtKB:Q13315] xref: UniProtKB:Q13315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:B0010654 name: ATM_HUMAN-Phosphoserine85 def: "Protein ATM_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q13315] xref: UniProtKB:Q13315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:B0010655 name: ATM_HUMAN-Phosphothreonine86 def: "Protein ATM_HUMAN with the residue 86 substituted with Phosphothreonine" [UniProtKB:Q13315] xref: UniProtKB:Q13315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:B0010656 name: ATM_HUMAN-Phosphoserine367 def: "Protein ATM_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q13315] xref: UniProtKB:Q13315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:B0010657 name: ATM_HUMAN-Phosphothreonine373 def: "Protein ATM_HUMAN with the residue 373 substituted with Phosphothreonine" [UniProtKB:Q13315] xref: UniProtKB:Q13315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:B0010658 name: ATM_HUMAN-Phosphoserine1981 def: "Protein ATM_HUMAN with the residue 1981 substituted with Phosphoserine" [UniProtKB:Q13315] comment: by autocatalysis; xref: UniProtKB:Q13315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:B0010659 name: ATM_HUMAN-Phosphothreonine1985 def: "Protein ATM_HUMAN with the residue 1985 substituted with Phosphothreonine" [UniProtKB:Q13315] xref: UniProtKB:Q13315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:B0010660 name: ATN1_HUMAN-Phosphoserine34 def: "Protein ATN1_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010661 name: ATN1_HUMAN-Phosphoserine77 def: "Protein ATN1_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010662 name: ATN1_HUMAN-Phosphoserine79 def: "Protein ATN1_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010663 name: ATN1_HUMAN-Phosphoserine101 def: "Protein ATN1_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010664 name: ATN1_HUMAN-Phosphoserine103 def: "Protein ATN1_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010665 name: ATN1_HUMAN-Phosphoserine107 def: "Protein ATN1_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010666 name: ATN1_HUMAN-Phosphoserine112 def: "Protein ATN1_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010667 name: ATN1_HUMAN-Phosphoserine119 def: "Protein ATN1_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010668 name: ATN1_HUMAN-Phosphoserine627 def: "Protein ATN1_HUMAN with the residue 627 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010669 name: ATN1_HUMAN-Phosphoserine640 def: "Protein ATN1_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010670 name: ATN1_HUMAN-Phosphothreonine648 def: "Protein ATN1_HUMAN with the residue 648 substituted with Phosphothreonine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010671 name: ATN1_HUMAN-Phosphoserine656 def: "Protein ATN1_HUMAN with the residue 656 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010672 name: ATN1_HUMAN-Phosphothreonine664 def: "Protein ATN1_HUMAN with the residue 664 substituted with Phosphothreonine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010673 name: ATN1_HUMAN-Phosphoserine734 def: "Protein ATN1_HUMAN with the residue 734 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010674 name: ATN1_HUMAN-Phosphoserine741 def: "Protein ATN1_HUMAN with the residue 741 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010675 name: ATN1_HUMAN-Phosphoserine743 def: "Protein ATN1_HUMAN with the residue 743 substituted with Phosphoserine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0010676 name: ATPA_HUMAN-Pyrrolidone carboxylic acid44 def: "Protein ATPA_HUMAN with the residue 44 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0005648 ! MHC class I protein binding relationship: has_function CCO:F0005863 ! eukaryotic cell surface binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006277 ! hydrogen ion transporting ATP synthase activity, rotational mechanism relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000337 ! mitochondrial proton-transporting ATP synthase complex relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: located_in CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010677 name: ATPA_HUMAN-Phosphoserine76 def: "Protein ATPA_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010678 name: ATPA_HUMAN-N6-acetyllysine132 def: "Protein ATPA_HUMAN with the residue 132 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010679 name: ATPA_HUMAN-N6-acetyllysine230 def: "Protein ATPA_HUMAN with the residue 230 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010680 name: ATPA_HUMAN-N6-acetyllysine239 def: "Protein ATPA_HUMAN with the residue 239 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010681 name: ATPA_HUMAN-N6-acetyllysine261 def: "Protein ATPA_HUMAN with the residue 261 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010682 name: ATPA_HUMAN-N6-acetyllysine305 def: "Protein ATPA_HUMAN with the residue 305 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010683 name: ATPA_HUMAN-N6-acetyllysine427 def: "Protein ATPA_HUMAN with the residue 427 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010684 name: ATPA_HUMAN-N6-acetyllysine498 def: "Protein ATPA_HUMAN with the residue 498 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010685 name: ATPA_HUMAN-N6-acetyllysine531 def: "Protein ATPA_HUMAN with the residue 531 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010686 name: ATPA_HUMAN-N6-acetyllysine539 def: "Protein ATPA_HUMAN with the residue 539 substituted with N6-acetyllysine" [UniProtKB:P25705] comment: By similarity xref: UniProtKB:P25705 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:B0010687 name: ATPB_HUMAN-N6-acetyllysine133 def: "Protein ATPB_HUMAN with the residue 133 substituted with N6-acetyllysine" [UniProtKB:P06576] comment: By similarity xref: UniProtKB:P06576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005827 ! ATPB_HUMAN [Term] id: CCO:B0010688 name: ATPB_HUMAN-N6-acetyllysine259 def: "Protein ATPB_HUMAN with the residue 259 substituted with N6-acetyllysine" [UniProtKB:P06576] comment: By similarity xref: UniProtKB:P06576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005827 ! ATPB_HUMAN [Term] id: CCO:B0010689 name: ATPB_HUMAN-N6-acetyllysine522 def: "Protein ATPB_HUMAN with the residue 522 substituted with N6-acetyllysine" [UniProtKB:P06576] comment: By similarity xref: UniProtKB:P06576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001990 ! hydrogen-exporting ATPase activity, phosphorylative mechanism relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005648 ! MHC class I protein binding relationship: has_function CCO:F0005863 ! eukaryotic cell surface binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006277 ! hydrogen ion transporting ATP synthase activity, rotational mechanism relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000337 ! mitochondrial proton-transporting ATP synthase complex relationship: located_in CCO:C0000338 ! mitochondrial proton-transporting ATP synthase, catalytic core relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: located_in CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) relationship: transformation_of CCO:B0005827 ! ATPB_HUMAN [Term] id: CCO:B0010690 name: ATPB_HUMAN-Phosphoserine529 def: "Protein ATPB_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:P06576] comment: By similarity xref: UniProtKB:P06576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005827 ! ATPB_HUMAN [Term] id: CCO:B0010691 name: ATPG_HUMAN-N6-acetyllysine79 def: "Protein ATPG_HUMAN with the residue 79 substituted with N6-acetyllysine" [UniProtKB:P36542] comment: By similarity xref: UniProtKB:P36542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:B0010692 name: ATPG_HUMAN-N6-acetyllysine90 def: "Protein ATPG_HUMAN with the residue 90 substituted with N6-acetyllysine" [UniProtKB:P36542] comment: By similarity xref: UniProtKB:P36542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006277 ! hydrogen ion transporting ATP synthase activity, rotational mechanism relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000048 ! mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000337 ! mitochondrial proton-transporting ATP synthase complex relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: located_in CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) relationship: transformation_of CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:B0010693 name: ATPG_HUMAN-N6-acetyllysine115 def: "Protein ATPG_HUMAN with the residue 115 substituted with N6-acetyllysine" [UniProtKB:P36542] comment: By similarity xref: UniProtKB:P36542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:B0010694 name: ATRIP_HUMAN-Phosphoserine518 def: "Protein ATRIP_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:Q8WXE1] xref: UniProtKB:Q8WXE1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0002009 ! ATRIP_HUMAN [Term] id: CCO:B0010695 name: ATRX_HUMAN-Phosphoserine34 def: "Protein ATRX_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010696 name: ATRX_HUMAN-Phosphoserine71 def: "Protein ATRX_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010697 name: ATRX_HUMAN-Phosphoserine74 def: "Protein ATRX_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010698 name: ATRX_HUMAN-Phosphothreonine87 def: "Protein ATRX_HUMAN with the residue 87 substituted with Phosphothreonine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010699 name: ATRX_HUMAN-Phosphoserine92 def: "Protein ATRX_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:P46100] comment: By similarity xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000310 ! nuclear heterochromatin relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010700 name: ATRX_HUMAN-Phosphoserine634 def: "Protein ATRX_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010701 name: ATRX_HUMAN-Phosphoserine729 def: "Protein ATRX_HUMAN with the residue 729 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010702 name: ATRX_HUMAN-Phosphoserine731 def: "Protein ATRX_HUMAN with the residue 731 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010703 name: ATRX_HUMAN-Phosphoserine849 def: "Protein ATRX_HUMAN with the residue 849 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010704 name: ATRX_HUMAN-Phosphoserine850 def: "Protein ATRX_HUMAN with the residue 850 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010705 name: ATRX_HUMAN-Phosphoserine871 def: "Protein ATRX_HUMAN with the residue 871 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010706 name: ATRX_HUMAN-Phosphoserine1348 def: "Protein ATRX_HUMAN with the residue 1348 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010707 name: ATRX_HUMAN-Phosphoserine1352 def: "Protein ATRX_HUMAN with the residue 1352 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010708 name: ATRX_HUMAN-Phosphoserine1527 def: "Protein ATRX_HUMAN with the residue 1527 substituted with Phosphoserine" [UniProtKB:P46100] xref: UniProtKB:P46100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:B0010709 name: ATR_HUMAN-Phosphoserine919 def: "Protein ATR_HUMAN with the residue 919 substituted with Phosphoserine" [UniProtKB:Q13535] xref: UniProtKB:Q13535 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001756 ! ATR_HUMAN [Term] id: CCO:B0010719 name: ATX7_HUMAN-Phosphoserine840 def: "Protein ATX7_HUMAN with the residue 840 substituted with Phosphoserine" [UniProtKB:O15265] xref: UniProtKB:O15265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:B0010720 name: ATX7_HUMAN-Phosphoserine849 def: "Protein ATX7_HUMAN with the residue 849 substituted with Phosphoserine" [UniProtKB:O15265] xref: UniProtKB:O15265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:B0010721 name: ATX7_HUMAN-Phosphothreonine854 def: "Protein ATX7_HUMAN with the residue 854 substituted with Phosphothreonine" [UniProtKB:O15265] xref: UniProtKB:O15265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:B0010722 name: AURKB_HUMAN-Phosphoserine7 def: "Protein AURKB_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q96GD4] xref: UniProtKB:Q96GD4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:B0010723 name: AURKB_HUMAN-Phosphotyrosine12 def: "Protein AURKB_HUMAN with the residue 12 substituted with Phosphotyrosine" [UniProtKB:Q96GD4] xref: UniProtKB:Q96GD4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0001017 ! midbody relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:B0010724 name: AURKB_HUMAN-Phosphothreonine232 def: "Protein AURKB_HUMAN with the residue 232 substituted with Phosphothreonine" [UniProtKB:Q96GD4] xref: UniProtKB:Q96GD4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:B0010725 name: BAD_HUMAN-Phosphoserine75 def: "Protein BAD_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q92934] comment: by PKA and PKB; By similarity xref: UniProtKB:Q92934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:B0010726 name: BAD_HUMAN-Phosphoserine99 def: "Protein BAD_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q92934] comment: by PKA and PKB; By similarity xref: UniProtKB:Q92934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:B0010727 name: BAD_HUMAN-Phosphoserine118 def: "Protein BAD_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q92934] comment: by PKA and PKB; By similarity xref: UniProtKB:Q92934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:B0010728 name: BAD_HUMAN-Phosphoserine134 def: "Protein BAD_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q92934] comment: By similarity xref: UniProtKB:Q92934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:B0010729 name: BAT2_HUMAN-Phosphoserine114 def: "Protein BAT2_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010730 name: BAT2_HUMAN-Phosphoserine204 def: "Protein BAT2_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010731 name: BAT2_HUMAN-Phosphoserine342 def: "Protein BAT2_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010732 name: BAT2_HUMAN-Phosphoserine350 def: "Protein BAT2_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010733 name: BAT2_HUMAN-Phosphoserine380 def: "Protein BAT2_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010734 name: BAT2_HUMAN-Phosphoserine456 def: "Protein BAT2_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010735 name: BAT2_HUMAN-Phosphothreonine517 def: "Protein BAT2_HUMAN with the residue 517 substituted with Phosphothreonine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010736 name: BAT2_HUMAN-Phosphothreonine610 def: "Protein BAT2_HUMAN with the residue 610 substituted with Phosphothreonine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010737 name: BAT2_HUMAN-Phosphoserine759 def: "Protein BAT2_HUMAN with the residue 759 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010738 name: BAT2_HUMAN-Phosphoserine761 def: "Protein BAT2_HUMAN with the residue 761 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010739 name: BAT2_HUMAN-Phosphoserine764 def: "Protein BAT2_HUMAN with the residue 764 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010740 name: BAT2_HUMAN-Phosphothreonine782 def: "Protein BAT2_HUMAN with the residue 782 substituted with Phosphothreonine" [UniProtKB:P48634] comment: By similarity xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010741 name: BAT2_HUMAN-Phosphoserine1004 def: "Protein BAT2_HUMAN with the residue 1004 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010742 name: BAT2_HUMAN-Phosphoserine1089 def: "Protein BAT2_HUMAN with the residue 1089 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010743 name: BAT2_HUMAN-Phosphoserine1092 def: "Protein BAT2_HUMAN with the residue 1092 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010744 name: BAT2_HUMAN-Phosphoserine1219 def: "Protein BAT2_HUMAN with the residue 1219 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010745 name: BAT2_HUMAN-Phosphothreonine1347 def: "Protein BAT2_HUMAN with the residue 1347 substituted with Phosphothreonine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010746 name: BAT2_HUMAN-Phosphothreonine1353 def: "Protein BAT2_HUMAN with the residue 1353 substituted with Phosphothreonine" [UniProtKB:P48634] comment: By similarity xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0010747 name: BAT3_HUMAN-Phosphoserine113 def: "Protein BAT3_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:P46379] xref: UniProtKB:P46379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:B0010748 name: BAT3_HUMAN-Phosphoserine964 def: "Protein BAT3_HUMAN with the residue 964 substituted with Phosphoserine" [UniProtKB:P46379] xref: UniProtKB:P46379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:B0010749 name: BAT3_HUMAN-Phosphoserine973 def: "Protein BAT3_HUMAN with the residue 973 substituted with Phosphoserine" [UniProtKB:P46379] xref: UniProtKB:P46379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:B0010750 name: BAT3_HUMAN-Phosphoserine1039 def: "Protein BAT3_HUMAN with the residue 1039 substituted with Phosphoserine" [UniProtKB:P46379] xref: UniProtKB:P46379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:B0010751 name: BAT3_HUMAN-Phosphotyrosine1042 def: "Protein BAT3_HUMAN with the residue 1042 substituted with Phosphotyrosine" [UniProtKB:P46379] xref: UniProtKB:P46379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:B0010752 name: BAT3_HUMAN-Phosphoserine1117 def: "Protein BAT3_HUMAN with the residue 1117 substituted with Phosphoserine" [UniProtKB:P46379] xref: UniProtKB:P46379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:B0010753 name: BCAR1_HUMAN-Phosphotyrosine128 def: "Protein BCAR1_HUMAN with the residue 128 substituted with Phosphotyrosine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010754 name: BCAR1_HUMAN-Phosphoserine139 def: "Protein BCAR1_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010755 name: BCAR1_HUMAN-Phosphotyrosine222 def: "Protein BCAR1_HUMAN with the residue 222 substituted with Phosphotyrosine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010756 name: BCAR1_HUMAN-Phosphotyrosine224 def: "Protein BCAR1_HUMAN with the residue 224 substituted with Phosphotyrosine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010757 name: BCAR1_HUMAN-Phosphotyrosine234 def: "Protein BCAR1_HUMAN with the residue 234 substituted with Phosphotyrosine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010758 name: BCAR1_HUMAN-Phosphotyrosine249 def: "Protein BCAR1_HUMAN with the residue 249 substituted with Phosphotyrosine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010759 name: BCAR1_HUMAN-Phosphotyrosine327 def: "Protein BCAR1_HUMAN with the residue 327 substituted with Phosphotyrosine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010760 name: BCAR1_HUMAN-Phosphotyrosine362 def: "Protein BCAR1_HUMAN with the residue 362 substituted with Phosphotyrosine" [UniProtKB:P56945] comment: By similarity xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004212 ! protein phosphatase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010761 name: BCAR1_HUMAN-Phosphotyrosine387 def: "Protein BCAR1_HUMAN with the residue 387 substituted with Phosphotyrosine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010762 name: BCAR1_HUMAN-Phosphotyrosine410 def: "Protein BCAR1_HUMAN with the residue 410 substituted with Phosphotyrosine" [UniProtKB:P56945] comment: By similarity xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010763 name: BCAR1_HUMAN-Phosphoserine639 def: "Protein BCAR1_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0010764 name: BCAR3_HUMAN-Phosphothreonine130 def: "Protein BCAR3_HUMAN with the residue 130 substituted with Phosphothreonine" [UniProtKB:O75815] xref: UniProtKB:O75815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001437 ! BCAR3_HUMAN [Term] id: CCO:B0010765 name: BCAR3_HUMAN-Phosphoserine182 def: "Protein BCAR3_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:O75815] xref: UniProtKB:O75815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001437 ! BCAR3_HUMAN [Term] id: CCO:B0010766 name: BCAR3_HUMAN-Phosphoserine290 def: "Protein BCAR3_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:O75815] xref: UniProtKB:O75815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001437 ! BCAR3_HUMAN [Term] id: CCO:B0010767 name: BCAR3_HUMAN-Phosphoserine370 def: "Protein BCAR3_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:O75815] comment: By similarity xref: UniProtKB:O75815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0001437 ! BCAR3_HUMAN [Term] id: CCO:B0010768 name: BCAR3_HUMAN-Phosphoserine375 def: "Protein BCAR3_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:O75815] xref: UniProtKB:O75815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001437 ! BCAR3_HUMAN [Term] id: CCO:B0010769 name: BCCIP_HUMAN-Phosphoserine12 def: "Protein BCCIP_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q9P287] xref: UniProtKB:Q9P287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002187 ! BCCIP_HUMAN [Term] id: CCO:B0010770 name: BCCIP_HUMAN-Phosphoserine42 def: "Protein BCCIP_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q9P287] xref: UniProtKB:Q9P287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002187 ! BCCIP_HUMAN [Term] id: CCO:B0010771 name: BCCIP_HUMAN-Phosphoserine112 def: "Protein BCCIP_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:Q9P287] xref: UniProtKB:Q9P287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002187 ! BCCIP_HUMAN [Term] id: CCO:B0010772 name: BCCIP_HUMAN-Phosphoserine115 def: "Protein BCCIP_HUMAN with the residue 115 substituted with Phosphoserine" [UniProtKB:Q9P287] xref: UniProtKB:Q9P287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002187 ! BCCIP_HUMAN [Term] id: CCO:B0010773 name: BCL2_HUMAN-Phosphoserine70 def: "Protein BCL2_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:P10415] comment: by PKC; By similarity xref: UniProtKB:P10415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000256 ! protease binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008116 ! BH3 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0001506 ! BCL2_HUMAN [Term] id: CCO:B0010774 name: BCL9_HUMAN-Phosphothreonine315 def: "Protein BCL9_HUMAN with the residue 315 substituted with Phosphothreonine" [UniProtKB:O00512] xref: UniProtKB:O00512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:B0010775 name: BCL9_HUMAN-Phosphoserine318 def: "Protein BCL9_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:O00512] xref: UniProtKB:O00512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:B0010776 name: BCL9_HUMAN-Phosphoserine352 def: "Protein BCL9_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:O00512] comment: By similarity xref: UniProtKB:O00512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:B0010777 name: BCL9_HUMAN-Phosphoserine687 def: "Protein BCL9_HUMAN with the residue 687 substituted with Phosphoserine" [UniProtKB:O00512] xref: UniProtKB:O00512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:B0010778 name: BCR_HUMAN-Phosphotyrosine177 def: "Protein BCR_HUMAN with the residue 177 substituted with Phosphotyrosine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0010779 name: BCR_HUMAN-Phosphothreonine310 def: "Protein BCR_HUMAN with the residue 310 substituted with Phosphothreonine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0010780 name: BCR_HUMAN-Phosphoserine459 def: "Protein BCR_HUMAN with the residue 459 substituted with Phosphoserine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0010781 name: BCR_HUMAN-Phosphoserine463 def: "Protein BCR_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0010782 name: BCR_HUMAN-Phosphotyrosine591 def: "Protein BCR_HUMAN with the residue 591 substituted with Phosphotyrosine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0010783 name: BCR_HUMAN-Phosphotyrosine644 def: "Protein BCR_HUMAN with the residue 644 substituted with Phosphotyrosine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0010784 name: BCR_HUMAN-Phosphoserine1264 def: "Protein BCR_HUMAN with the residue 1264 substituted with Phosphoserine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0010785 name: BEGIN_HUMAN-Phosphoserine194 def: "Protein BEGIN_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q9BUH8] comment: By similarity xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0010786 name: BEGIN_HUMAN-Phosphoserine246 def: "Protein BEGIN_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q9BUH8] xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0010787 name: BEGIN_HUMAN-Phosphoserine265 def: "Protein BEGIN_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q9BUH8] comment: By similarity xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0010788 name: BEGIN_HUMAN-Phosphoserine465 def: "Protein BEGIN_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q9BUH8] xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0010789 name: BEGIN_HUMAN-Phosphoserine483 def: "Protein BEGIN_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:Q9BUH8] xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0010790 name: BEGIN_HUMAN-Phosphoserine502 def: "Protein BEGIN_HUMAN with the residue 502 substituted with Phosphoserine" [UniProtKB:Q9BUH8] xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0010791 name: BEGIN_HUMAN-Phosphoserine563 def: "Protein BEGIN_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:Q9BUH8] xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0010792 name: BID_HUMAN-Phosphotyrosine54 def: "Protein BID_HUMAN with the residue 54 substituted with Phosphotyrosine" [UniProtKB:P55957] xref: UniProtKB:P55957 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005422 ! BID_HUMAN [Term] id: CCO:B0010793 name: BID_HUMAN-Phosphoserine78 def: "Protein BID_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:P55957] xref: UniProtKB:P55957 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005422 ! BID_HUMAN [Term] id: CCO:B0010794 name: BIN1_HUMAN-Phosphoserine296 def: "Protein BIN1_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:O00499] xref: UniProtKB:O00499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0001349 ! BIN1_HUMAN [Term] id: CCO:B0010795 name: BIN1_HUMAN-Phosphoserine298 def: "Protein BIN1_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:O00499] xref: UniProtKB:O00499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001349 ! BIN1_HUMAN [Term] id: CCO:B0010796 name: BIN1_HUMAN-Phosphoserine303 def: "Protein BIN1_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:O00499] xref: UniProtKB:O00499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001349 ! BIN1_HUMAN [Term] id: CCO:B0010797 name: BIN1_HUMAN-Phosphothreonine307 def: "Protein BIN1_HUMAN with the residue 307 substituted with Phosphothreonine" [UniProtKB:O00499] comment: By similarity xref: UniProtKB:O00499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001349 ! BIN1_HUMAN [Term] id: CCO:B0010798 name: BIN1_HUMAN-Phosphoserine331 def: "Protein BIN1_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:O00499] xref: UniProtKB:O00499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001349 ! BIN1_HUMAN [Term] id: CCO:B0010799 name: BIRC5_HUMAN-Phosphothreonine34 def: "Protein BIRC5_HUMAN with the residue 34 substituted with Phosphothreonine" [UniProtKB:O15392] comment: by CDC2; xref: UniProtKB:O15392 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005787 ! caspase inhibitor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007309 ! cofactor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000384 ! centriole relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000436 ! spindle microtubule relationship: located_in CCO:C0000439 ! cytoplasmic microtubule relationship: located_in CCO:C0001017 ! midbody relationship: located_in CCO:C0001113 ! interphase microtubule organizing center relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001377 ! BIRC5_HUMAN [Term] id: CCO:B0010800 name: BLM_HUMAN-Phosphoserine419 def: "Protein BLM_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0010801 name: BLM_HUMAN-Phosphoserine422 def: "Protein BLM_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0010802 name: BLM_HUMAN-Phosphoserine480 def: "Protein BLM_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0010803 name: BLM_HUMAN-Phosphoserine499 def: "Protein BLM_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000087 ! bubble DNA binding relationship: has_function CCO:F0000099 ! DNA strand annealing activity relationship: has_function CCO:F0000257 ! p53 binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0002383 ! four-way junction helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0005802 ! ATP-dependent 3'-5' DNA helicase activity relationship: has_function CCO:F0008203 ! G-quadruplex DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000127 ! lateral element relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000265 ! replication fork relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0010804 name: BLM_HUMAN-Phosphothreonine508 def: "Protein BLM_HUMAN with the residue 508 substituted with Phosphothreonine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0010805 name: BLM_HUMAN-Phosphoserine1296 def: "Protein BLM_HUMAN with the residue 1296 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0010806 name: BMCC1_HUMAN-Phosphoserine217 def: "Protein BMCC1_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:Q58A63] xref: UniProtKB:Q58A63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001842 ! BMCC1_HUMAN [Term] id: CCO:B0010807 name: BMCC1_HUMAN-Phosphoserine227 def: "Protein BMCC1_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q58A63] xref: UniProtKB:Q58A63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001842 ! BMCC1_HUMAN [Term] id: CCO:B0010808 name: BMCC1_HUMAN-Phosphoserine236 def: "Protein BMCC1_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:Q58A63] xref: UniProtKB:Q58A63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001842 ! BMCC1_HUMAN [Term] id: CCO:B0010809 name: BMCC1_HUMAN-Phosphoserine238 def: "Protein BMCC1_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q58A63] xref: UniProtKB:Q58A63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001842 ! BMCC1_HUMAN [Term] id: CCO:B0010810 name: BMCC1_HUMAN-Phosphoserine340 def: "Protein BMCC1_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q58A63] xref: UniProtKB:Q58A63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001842 ! BMCC1_HUMAN [Term] id: CCO:B0010811 name: BMR1A_HUMAN-Phosphoserine215 def: "Protein BMR1A_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:P36894] xref: UniProtKB:P36894 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005437 ! BMR1A_HUMAN [Term] id: CCO:B0010812 name: BMR1A_HUMAN-Phosphoserine216 def: "Protein BMR1A_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:P36894] xref: UniProtKB:P36894 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005437 ! BMR1A_HUMAN [Term] id: CCO:B0010813 name: BMR1A_HUMAN-Phosphoserine218 def: "Protein BMR1A_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:P36894] xref: UniProtKB:P36894 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005437 ! BMR1A_HUMAN [Term] id: CCO:B0010814 name: BMR1A_HUMAN-Phosphoserine220 def: "Protein BMR1A_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:P36894] xref: UniProtKB:P36894 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005437 ! BMR1A_HUMAN [Term] id: CCO:B0010815 name: BMX_HUMAN-Phosphotyrosine566 def: "Protein BMX_HUMAN with the residue 566 substituted with Phosphotyrosine" [UniProtKB:P51813] comment: by autocatalysis; By similarity xref: UniProtKB:P51813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005923 ! BMX_HUMAN [Term] id: CCO:B0010816 name: BNI3L_HUMAN-Phosphoserine62 def: "Protein BNI3L_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:O60238] comment: By similarity xref: UniProtKB:O60238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:B0010817 name: BNI3L_HUMAN-Phosphoserine63 def: "Protein BNI3L_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:O60238] comment: By similarity xref: UniProtKB:O60238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:B0010818 name: BNI3L_HUMAN-Phosphoserine117 def: "Protein BNI3L_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:O60238] comment: By similarity xref: UniProtKB:O60238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:B0010819 name: BNI3L_HUMAN-Phosphoserine120 def: "Protein BNI3L_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:O60238] xref: UniProtKB:O60238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:B0010820 name: BNIP3_HUMAN-Phosphoserine86 def: "Protein BNIP3_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q12983] comment: By similarity xref: UniProtKB:Q12983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001194 ! integral to mitochondrial outer membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: transformation_of CCO:B0005678 ! BNIP3_HUMAN [Term] id: CCO:B0010821 name: BNIP3_HUMAN-Phosphoserine92 def: "Protein BNIP3_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q12983] comment: By similarity xref: UniProtKB:Q12983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005678 ! BNIP3_HUMAN [Term] id: CCO:B0010822 name: BNIP3_HUMAN-Phosphoserine95 def: "Protein BNIP3_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q12983] comment: By similarity xref: UniProtKB:Q12983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005678 ! BNIP3_HUMAN [Term] id: CCO:B0010823 name: BOREA_HUMAN-Phosphothreonine106 def: "Protein BOREA_HUMAN with the residue 106 substituted with Phosphothreonine" [UniProtKB:Q53HL2] xref: UniProtKB:Q53HL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001839 ! BOREA_HUMAN [Term] id: CCO:B0010824 name: BOREA_HUMAN-Phosphoserine165 def: "Protein BOREA_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q53HL2] comment: Probable xref: UniProtKB:Q53HL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001839 ! BOREA_HUMAN [Term] id: CCO:B0010825 name: BOREA_HUMAN-Phosphoserine219 def: "Protein BOREA_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q53HL2] xref: UniProtKB:Q53HL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001839 ! BOREA_HUMAN [Term] id: CCO:B0010826 name: BPAEA_HUMAN-Phosphoserine1558 def: "Protein BPAEA_HUMAN with the residue 1558 substituted with Phosphoserine" [UniProtKB:O94833] xref: UniProtKB:O94833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001443 ! BPAEA_HUMAN [Term] id: CCO:B0010827 name: BPAEA_HUMAN-Phosphoserine5111 def: "Protein BPAEA_HUMAN with the residue 5111 substituted with Phosphoserine" [UniProtKB:O94833] xref: UniProtKB:O94833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001443 ! BPAEA_HUMAN [Term] id: CCO:B0010828 name: BPAEA_HUMAN-Phosphoserine5114 def: "Protein BPAEA_HUMAN with the residue 5114 substituted with Phosphoserine" [UniProtKB:O94833] xref: UniProtKB:O94833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001443 ! BPAEA_HUMAN [Term] id: CCO:B0010829 name: BPAEA_HUMAN-Phosphoserine5163 def: "Protein BPAEA_HUMAN with the residue 5163 substituted with Phosphoserine" [UniProtKB:O94833] xref: UniProtKB:O94833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001443 ! BPAEA_HUMAN [Term] id: CCO:B0010830 name: BRAF1_HUMAN-Phosphoserine151 def: "Protein BRAF1_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010831 name: BRAF1_HUMAN-Phosphoserine365 def: "Protein BRAF1_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010832 name: BRAF1_HUMAN-Phosphothreonine373 def: "Protein BRAF1_HUMAN with the residue 373 substituted with Phosphothreonine" [UniProtKB:P15056] comment: by autocatalysis; xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010833 name: BRAF1_HUMAN-Phosphothreonine401 def: "Protein BRAF1_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010834 name: BRAF1_HUMAN-Phosphoserine419 def: "Protein BRAF1_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010835 name: BRAF1_HUMAN-Phosphoserine446 def: "Protein BRAF1_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010836 name: BRAF1_HUMAN-Phosphoserine729 def: "Protein BRAF1_HUMAN with the residue 729 substituted with Phosphoserine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010837 name: BRAF1_HUMAN-Phosphoserine750 def: "Protein BRAF1_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0010838 name: BRAP_HUMAN-Phosphoserine117 def: "Protein BRAP_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q7Z569] comment: By similarity xref: UniProtKB:Q7Z569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:B0010839 name: BRCA1_HUMAN-Phosphoserine840 def: "Protein BRCA1_HUMAN with the residue 840 substituted with Phosphoserine" [UniProtKB:P38398] comment: By similarity xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010840 name: BRCA1_HUMAN-Phosphoserine1143 def: "Protein BRCA1_HUMAN with the residue 1143 substituted with Phosphoserine" [UniProtKB:P38398] comment: by ATR; in vitro; xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010841 name: BRCA1_HUMAN-Phosphoserine1211 def: "Protein BRCA1_HUMAN with the residue 1211 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010842 name: BRCA1_HUMAN-Phosphoserine1212 def: "Protein BRCA1_HUMAN with the residue 1212 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010843 name: BRCA1_HUMAN-Phosphoserine1217 def: "Protein BRCA1_HUMAN with the residue 1217 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010844 name: BRCA1_HUMAN-Phosphoserine1218 def: "Protein BRCA1_HUMAN with the residue 1218 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010845 name: BRCA1_HUMAN-Phosphoserine1239 def: "Protein BRCA1_HUMAN with the residue 1239 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010846 name: BRCA1_HUMAN-Phosphoserine1245 def: "Protein BRCA1_HUMAN with the residue 1245 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010847 name: BRCA1_HUMAN-Phosphoserine1280 def: "Protein BRCA1_HUMAN with the residue 1280 substituted with Phosphoserine" [UniProtKB:P38398] comment: by ATR; in vitro; xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010848 name: BRCA1_HUMAN-Phosphoserine1330 def: "Protein BRCA1_HUMAN with the residue 1330 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010849 name: BRCA1_HUMAN-Phosphoserine1336 def: "Protein BRCA1_HUMAN with the residue 1336 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010850 name: BRCA1_HUMAN-Phosphoserine1342 def: "Protein BRCA1_HUMAN with the residue 1342 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010851 name: BRCA1_HUMAN-Phosphoserine1387 def: "Protein BRCA1_HUMAN with the residue 1387 substituted with Phosphoserine" [UniProtKB:P38398] comment: by ATM and ATR; xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010852 name: BRCA1_HUMAN-Phosphothreonine1394 def: "Protein BRCA1_HUMAN with the residue 1394 substituted with Phosphothreonine" [UniProtKB:P38398] comment: by ATR; in vitro; xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010853 name: BRCA1_HUMAN-Phosphoserine1423 def: "Protein BRCA1_HUMAN with the residue 1423 substituted with Phosphoserine" [UniProtKB:P38398] comment: by ATM and ATR; xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000536 ! gamma-tubulin ring complex relationship: located_in CCO:C0001247 ! BRCA1-BARD1 complex relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010854 name: BRCA1_HUMAN-Phosphoserine1457 def: "Protein BRCA1_HUMAN with the residue 1457 substituted with Phosphoserine" [UniProtKB:P38398] comment: by ATR; in vitro; xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010855 name: BRCA1_HUMAN-Phosphoserine1466 def: "Protein BRCA1_HUMAN with the residue 1466 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010856 name: BRCA1_HUMAN-Phosphoserine1524 def: "Protein BRCA1_HUMAN with the residue 1524 substituted with Phosphoserine" [UniProtKB:P38398] comment: by ATM; xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010857 name: BRCA1_HUMAN-Phosphothreonine1700 def: "Protein BRCA1_HUMAN with the residue 1700 substituted with Phosphothreonine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010858 name: BRCA1_HUMAN-Phosphothreonine1720 def: "Protein BRCA1_HUMAN with the residue 1720 substituted with Phosphothreonine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0010859 name: BRCA2_HUMAN-Phosphoserine683 def: "Protein BRCA2_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:P51587] xref: UniProtKB:P51587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001649 ! BRCA2_HUMAN [Term] id: CCO:B0010860 name: BRCA2_HUMAN-Phosphoserine755 def: "Protein BRCA2_HUMAN with the residue 755 substituted with Phosphoserine" [UniProtKB:P51587] xref: UniProtKB:P51587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001649 ! BRCA2_HUMAN [Term] id: CCO:B0010861 name: BRD4_HUMAN-Phosphoserine470 def: "Protein BRD4_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:O60885] xref: UniProtKB:O60885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006311 ! BRD4_HUMAN [Term] id: CCO:B0010862 name: BRD4_HUMAN-Phosphoserine601 def: "Protein BRD4_HUMAN with the residue 601 substituted with Phosphoserine" [UniProtKB:O60885] xref: UniProtKB:O60885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006311 ! BRD4_HUMAN [Term] id: CCO:B0010863 name: BRD4_HUMAN-Phosphoserine1045 def: "Protein BRD4_HUMAN with the residue 1045 substituted with Phosphoserine" [UniProtKB:O60885] xref: UniProtKB:O60885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006311 ! BRD4_HUMAN [Term] id: CCO:B0010864 name: BRD4_HUMAN-Phosphoserine1117 def: "Protein BRD4_HUMAN with the residue 1117 substituted with Phosphoserine" [UniProtKB:O60885] xref: UniProtKB:O60885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006311 ! BRD4_HUMAN [Term] id: CCO:B0010865 name: BRD7_HUMAN-Phosphoserine279 def: "Protein BRD7_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q9NPI1] xref: UniProtKB:Q9NPI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005400 ! BRD7_HUMAN [Term] id: CCO:B0010866 name: BRSK1_HUMAN-Phosphothreonine205 def: "Protein BRSK1_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:Q8TDC3] xref: UniProtKB:Q8TDC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001992 ! BRSK1_HUMAN [Term] id: CCO:B0010867 name: BRSK1_HUMAN-Phosphoserine209 def: "Protein BRSK1_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q8TDC3] comment: By similarity xref: UniProtKB:Q8TDC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001992 ! BRSK1_HUMAN [Term] id: CCO:B0010868 name: BTBDA_HUMAN-Phosphotyrosine377 def: "Protein BTBDA_HUMAN with the residue 377 substituted with Phosphotyrosine" [UniProtKB:Q9BSF8] xref: UniProtKB:Q9BSF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006271 ! BTBDA_HUMAN [Term] id: CCO:B0010869 name: BUB1_HUMAN-Phosphoserine314 def: "Protein BUB1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:O43683] xref: UniProtKB:O43683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001395 ! BUB1_HUMAN [Term] id: CCO:B0010870 name: BUB3_HUMAN-Phosphoserine211 def: "Protein BUB3_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:O43684] xref: UniProtKB:O43684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001396 ! BUB3_HUMAN [Term] id: CCO:B0010871 name: CABL1_HUMAN-Phosphoserine168 def: "Protein CABL1_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q8TDN4] xref: UniProtKB:Q8TDN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001994 ! CABL1_HUMAN [Term] id: CCO:B0010872 name: CABL1_HUMAN-Phosphoserine313 def: "Protein CABL1_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q8TDN4] comment: by CDK2 and CDK3; By similarity xref: UniProtKB:Q8TDN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001994 ! CABL1_HUMAN [Term] id: CCO:B0010873 name: CAC1A_HUMAN-Phosphoserine750 def: "Protein CAC1A_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:O00555] comment: By similarity xref: UniProtKB:O00555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006044 ! CAC1A_HUMAN [Term] id: CCO:B0010874 name: CAC1A_HUMAN-Phosphoserine1822 def: "Protein CAC1A_HUMAN with the residue 1822 substituted with Phosphoserine" [UniProtKB:O00555] comment: by PKA; Potential xref: UniProtKB:O00555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006044 ! CAC1A_HUMAN [Term] id: CCO:B0010875 name: CAC1A_HUMAN-Phosphoserine2030 def: "Protein CAC1A_HUMAN with the residue 2030 substituted with Phosphoserine" [UniProtKB:O00555] comment: By similarity xref: UniProtKB:O00555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001513 ! voltage-gated calcium channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000448 ! voltage-gated calcium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0006044 ! CAC1A_HUMAN [Term] id: CCO:B0010876 name: CAC1A_HUMAN-Phosphotyrosine2076 def: "Protein CAC1A_HUMAN with the residue 2076 substituted with Phosphotyrosine" [UniProtKB:O00555] comment: By similarity xref: UniProtKB:O00555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006044 ! CAC1A_HUMAN [Term] id: CCO:B0010877 name: CAC1A_HUMAN-Phosphoserine2269 def: "Protein CAC1A_HUMAN with the residue 2269 substituted with Phosphoserine" [UniProtKB:O00555] comment: By similarity xref: UniProtKB:O00555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006044 ! CAC1A_HUMAN [Term] id: CCO:B0010878 name: CAC1A_HUMAN-Phosphoserine2378 def: "Protein CAC1A_HUMAN with the residue 2378 substituted with Phosphoserine" [UniProtKB:O00555] comment: By similarity xref: UniProtKB:O00555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006044 ! CAC1A_HUMAN [Term] id: CCO:B0010879 name: CAC1C_HUMAN-Phosphoserine815 def: "Protein CAC1C_HUMAN with the residue 815 substituted with Phosphoserine" [UniProtKB:Q13936] comment: By similarity xref: UniProtKB:Q13936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005692 ! CAC1C_HUMAN [Term] id: CCO:B0010880 name: CAC1C_HUMAN-Phosphoserine1535 def: "Protein CAC1C_HUMAN with the residue 1535 substituted with Phosphoserine" [UniProtKB:Q13936] comment: by PKA; Potential xref: UniProtKB:Q13936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005692 ! CAC1C_HUMAN [Term] id: CCO:B0010881 name: CAC1C_HUMAN-Phosphoserine1973 def: "Protein CAC1C_HUMAN with the residue 1973 substituted with Phosphoserine" [UniProtKB:Q13936] comment: by PKA; Potential xref: UniProtKB:Q13936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005692 ! CAC1C_HUMAN [Term] id: CCO:B0010882 name: CAC1C_HUMAN-Phosphoserine1981 def: "Protein CAC1C_HUMAN with the residue 1981 substituted with Phosphoserine" [UniProtKB:Q13936] comment: by PKA; Potential xref: UniProtKB:Q13936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005692 ! CAC1C_HUMAN [Term] id: CCO:B0010883 name: CACB4_HUMAN-Phosphoserine39 def: "Protein CACB4_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:O00305] comment: By similarity xref: UniProtKB:O00305 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006176 ! CACB4_HUMAN [Term] id: CCO:B0010884 name: CACB4_HUMAN-Phosphothreonine405 def: "Protein CACB4_HUMAN with the residue 405 substituted with Phosphothreonine" [UniProtKB:O00305] comment: By similarity xref: UniProtKB:O00305 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006176 ! CACB4_HUMAN [Term] id: CCO:B0010885 name: CACB4_HUMAN-Phosphoserine406 def: "Protein CACB4_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:O00305] comment: By similarity xref: UniProtKB:O00305 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006176 ! CACB4_HUMAN [Term] id: CCO:B0010886 name: CACB4_HUMAN-Phosphothreonine411 def: "Protein CACB4_HUMAN with the residue 411 substituted with Phosphothreonine" [UniProtKB:O00305] comment: By similarity xref: UniProtKB:O00305 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006176 ! CACB4_HUMAN [Term] id: CCO:B0010887 name: CACB4_HUMAN-Phosphoserine508 def: "Protein CACB4_HUMAN with the residue 508 substituted with Phosphoserine" [UniProtKB:O00305] comment: By similarity xref: UniProtKB:O00305 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001513 ! voltage-gated calcium channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000448 ! voltage-gated calcium channel complex relationship: located_in CCO:C0000703 ! internal side of plasma membrane relationship: transformation_of CCO:B0006176 ! CACB4_HUMAN [Term] id: CCO:B0010888 name: CADH1_HUMAN-Phosphoserine838 def: "Protein CADH1_HUMAN with the residue 838 substituted with Phosphoserine" [UniProtKB:P12830] comment: By similarity xref: UniProtKB:P12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0008023 ! cell adhesion molecule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000465 ! cell-cell adherens junction relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000783 ! lateral plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0005581 ! CADH1_HUMAN [Term] id: CCO:B0010889 name: CADH1_HUMAN-Phosphoserine840 def: "Protein CADH1_HUMAN with the residue 840 substituted with Phosphoserine" [UniProtKB:P12830] comment: By similarity xref: UniProtKB:P12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005581 ! CADH1_HUMAN [Term] id: CCO:B0010890 name: CADH1_HUMAN-Phosphoserine846 def: "Protein CADH1_HUMAN with the residue 846 substituted with Phosphoserine" [UniProtKB:P12830] comment: By similarity xref: UniProtKB:P12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005581 ! CADH1_HUMAN [Term] id: CCO:B0010891 name: CAF1A_HUMAN-Phosphoserine47 def: "Protein CAF1A_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010892 name: CAF1A_HUMAN-Phosphoserine123 def: "Protein CAF1A_HUMAN with the residue 123 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000281 ! chromatin assembly complex relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010893 name: CAF1A_HUMAN-Phosphoserine181 def: "Protein CAF1A_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010894 name: CAF1A_HUMAN-Phosphoserine185 def: "Protein CAF1A_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010895 name: CAF1A_HUMAN-Phosphoserine188 def: "Protein CAF1A_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010896 name: CAF1A_HUMAN-Phosphoserine237 def: "Protein CAF1A_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010897 name: CAF1A_HUMAN-Phosphothreonine241 def: "Protein CAF1A_HUMAN with the residue 241 substituted with Phosphothreonine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010898 name: CAF1A_HUMAN-Phosphoserine754 def: "Protein CAF1A_HUMAN with the residue 754 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010899 name: CAF1A_HUMAN-Phosphoserine933 def: "Protein CAF1A_HUMAN with the residue 933 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0010900 name: CAF1B_HUMAN-Phosphoserine429 def: "Protein CAF1B_HUMAN with the residue 429 substituted with Phosphoserine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010901 name: CAF1B_HUMAN-Phosphoserine458 def: "Protein CAF1B_HUMAN with the residue 458 substituted with Phosphoserine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010902 name: CAF1B_HUMAN-Phosphothreonine485 def: "Protein CAF1B_HUMAN with the residue 485 substituted with Phosphothreonine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010903 name: CAF1B_HUMAN-Phosphothreonine495 def: "Protein CAF1B_HUMAN with the residue 495 substituted with Phosphothreonine" [UniProtKB:Q13112] comment: Potential xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000281 ! chromatin assembly complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010904 name: CAF1B_HUMAN-Phosphothreonine503 def: "Protein CAF1B_HUMAN with the residue 503 substituted with Phosphothreonine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010905 name: CAF1B_HUMAN-Phosphothreonine509 def: "Protein CAF1B_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q13112] comment: Potential xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010906 name: CAF1B_HUMAN-Phosphothreonine521 def: "Protein CAF1B_HUMAN with the residue 521 substituted with Phosphothreonine" [UniProtKB:Q13112] comment: Potential xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010907 name: CAF1B_HUMAN-Phosphothreonine531 def: "Protein CAF1B_HUMAN with the residue 531 substituted with Phosphothreonine" [UniProtKB:Q13112] comment: Potential xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010908 name: CAF1B_HUMAN-Phosphoserine538 def: "Protein CAF1B_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0010909 name: CALM_HUMAN-N-acetylalanine2 def: "Protein CALM_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62158] xref: UniProtKB:P62158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001690 ! CALM_HUMAN [Term] id: CCO:B0010910 name: CALM_HUMAN-Phosphothreonine45 def: "Protein CALM_HUMAN with the residue 45 substituted with Phosphothreonine" [UniProtKB:P62158] comment: by CaMK4; By similarity xref: UniProtKB:P62158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001690 ! CALM_HUMAN [Term] id: CCO:B0010911 name: CALM_HUMAN-Phosphotyrosine100 def: "Protein CALM_HUMAN with the residue 100 substituted with Phosphotyrosine" [UniProtKB:P62158] xref: UniProtKB:P62158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001690 ! CALM_HUMAN [Term] id: CCO:B0010912 name: CALM_HUMAN-N6,N6,N6-trimethyllysine116 def: "Protein CALM_HUMAN with the residue 116 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P62158] xref: UniProtKB:P62158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0004922 ! N-terminal myristoylation domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0001690 ! CALM_HUMAN [Term] id: CCO:B0010913 name: CAPZB_HUMAN-N-acetylserine2 def: "Protein CAPZB_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P47756] xref: UniProtKB:P47756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006125 ! CAPZB_HUMAN [Term] id: CCO:B0010914 name: CAPZB_HUMAN-Phosphoserine182 def: "Protein CAPZB_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:P47756] comment: By similarity xref: UniProtKB:P47756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006125 ! CAPZB_HUMAN [Term] id: CCO:B0010915 name: CASC5_HUMAN-Phosphoserine32 def: "Protein CASC5_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010916 name: CASC5_HUMAN-Phosphoserine60 def: "Protein CASC5_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010917 name: CASC5_HUMAN-Phosphoserine765 def: "Protein CASC5_HUMAN with the residue 765 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010918 name: CASC5_HUMAN-Phosphoserine767 def: "Protein CASC5_HUMAN with the residue 767 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010919 name: CASC5_HUMAN-Phosphoserine956 def: "Protein CASC5_HUMAN with the residue 956 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010920 name: CASC5_HUMAN-Phosphoserine1039 def: "Protein CASC5_HUMAN with the residue 1039 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010921 name: CASC5_HUMAN-Phosphothreonine1042 def: "Protein CASC5_HUMAN with the residue 1042 substituted with Phosphothreonine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010922 name: CASC5_HUMAN-Phosphoserine1076 def: "Protein CASC5_HUMAN with the residue 1076 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010923 name: CASC5_HUMAN-Phosphoserine1773 def: "Protein CASC5_HUMAN with the residue 1773 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0010924 name: CASL_HUMAN-Phosphotyrosine12 def: "Protein CASL_HUMAN with the residue 12 substituted with Phosphotyrosine" [UniProtKB:Q14511] xref: UniProtKB:Q14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001782 ! CASL_HUMAN [Term] id: CCO:B0010925 name: CASL_HUMAN-Phosphotyrosine92 def: "Protein CASL_HUMAN with the residue 92 substituted with Phosphotyrosine" [UniProtKB:Q14511] comment: By similarity xref: UniProtKB:Q14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001782 ! CASL_HUMAN [Term] id: CCO:B0010926 name: CASL_HUMAN-Phosphotyrosine166 def: "Protein CASL_HUMAN with the residue 166 substituted with Phosphotyrosine" [UniProtKB:Q14511] xref: UniProtKB:Q14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0001782 ! CASL_HUMAN [Term] id: CCO:B0010927 name: CASL_HUMAN-Phosphotyrosine177 def: "Protein CASL_HUMAN with the residue 177 substituted with Phosphotyrosine" [UniProtKB:Q14511] comment: By similarity xref: UniProtKB:Q14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001782 ! CASL_HUMAN [Term] id: CCO:B0010928 name: CASL_HUMAN-Phosphotyrosine189 def: "Protein CASL_HUMAN with the residue 189 substituted with Phosphotyrosine" [UniProtKB:Q14511] comment: By similarity xref: UniProtKB:Q14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001782 ! CASL_HUMAN [Term] id: CCO:B0010929 name: CAV1_HUMAN-N-acetylserine2 def: "Protein CAV1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q03135] xref: UniProtKB:Q03135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005456 ! CAV1_HUMAN [Term] id: CCO:B0010930 name: CAV1_HUMAN-Phosphotyrosine6 def: "Protein CAV1_HUMAN with the residue 6 substituted with Phosphotyrosine" [UniProtKB:Q03135] xref: UniProtKB:Q03135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0003185 ! protease activator activity relationship: has_function CCO:F0008027 ! nitric-oxide synthase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000382 ! lipid particle relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0005456 ! CAV1_HUMAN [Term] id: CCO:B0010931 name: CAV1_HUMAN-Phosphotyrosine14 def: "Protein CAV1_HUMAN with the residue 14 substituted with Phosphotyrosine" [UniProtKB:Q03135] xref: UniProtKB:Q03135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005456 ! CAV1_HUMAN [Term] id: CCO:B0010932 name: CAV1_HUMAN-Phosphotyrosine25 def: "Protein CAV1_HUMAN with the residue 25 substituted with Phosphotyrosine" [UniProtKB:Q03135] xref: UniProtKB:Q03135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005456 ! CAV1_HUMAN [Term] id: CCO:B0010933 name: CAV1_HUMAN-Phosphoserine37 def: "Protein CAV1_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q03135] xref: UniProtKB:Q03135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005456 ! CAV1_HUMAN [Term] id: CCO:B0010934 name: CAV2_HUMAN-Phosphotyrosine19 def: "Protein CAV2_HUMAN with the residue 19 substituted with Phosphotyrosine" [UniProtKB:P51636] xref: UniProtKB:P51636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005462 ! CAV2_HUMAN [Term] id: CCO:B0010935 name: CAV2_HUMAN-Phosphoserine20 def: "Protein CAV2_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P51636] xref: UniProtKB:P51636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005462 ! CAV2_HUMAN [Term] id: CCO:B0010936 name: CAV2_HUMAN-Phosphoserine23 def: "Protein CAV2_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:P51636] xref: UniProtKB:P51636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005462 ! CAV2_HUMAN [Term] id: CCO:B0010937 name: CAV2_HUMAN-Phosphotyrosine27 def: "Protein CAV2_HUMAN with the residue 27 substituted with Phosphotyrosine" [UniProtKB:P51636] xref: UniProtKB:P51636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008027 ! nitric-oxide synthase binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0000978 ! transport vesicle relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0005462 ! CAV2_HUMAN [Term] id: CCO:B0010938 name: CAV2_HUMAN-Phosphoserine36 def: "Protein CAV2_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P51636] xref: UniProtKB:P51636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005462 ! CAV2_HUMAN [Term] id: CCO:B0010939 name: CBLB_HUMAN-Phosphoserine480 def: "Protein CBLB_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0010940 name: CBLB_HUMAN-Phosphoserine484 def: "Protein CBLB_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0010941 name: CBLB_HUMAN-Phosphotyrosine665 def: "Protein CBLB_HUMAN with the residue 665 substituted with Phosphotyrosine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0010942 name: CBLB_HUMAN-Phosphotyrosine709 def: "Protein CBLB_HUMAN with the residue 709 substituted with Phosphotyrosine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0010943 name: CBLB_HUMAN-Phosphotyrosine889 def: "Protein CBLB_HUMAN with the residue 889 substituted with Phosphotyrosine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0010944 name: CBL_HUMAN-Phosphotyrosine371 def: "Protein CBL_HUMAN with the residue 371 substituted with Phosphotyrosine" [UniProtKB:P22681] comment: by INSR; xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010945 name: CBL_HUMAN-Phosphotyrosine552 def: "Protein CBL_HUMAN with the residue 552 substituted with Phosphotyrosine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010946 name: CBL_HUMAN-Phosphoserine667 def: "Protein CBL_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010947 name: CBL_HUMAN-Phosphoserine669 def: "Protein CBL_HUMAN with the residue 669 substituted with Phosphoserine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010948 name: CBL_HUMAN-Phosphotyrosine674 def: "Protein CBL_HUMAN with the residue 674 substituted with Phosphotyrosine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010949 name: CBL_HUMAN-Phosphoserine675 def: "Protein CBL_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010950 name: CBL_HUMAN-Phosphotyrosine700 def: "Protein CBL_HUMAN with the residue 700 substituted with Phosphotyrosine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010951 name: CBL_HUMAN-Phosphotyrosine774 def: "Protein CBL_HUMAN with the residue 774 substituted with Phosphotyrosine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010952 name: CBL_HUMAN-Phosphoserine900 def: "Protein CBL_HUMAN with the residue 900 substituted with Phosphoserine" [UniProtKB:P22681] xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0010953 name: CBP_HUMAN-Phosphoserine124 def: "Protein CBP_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010954 name: CBP_HUMAN-Omega-N-methylated arginine601 def: "Protein CBP_HUMAN with the residue 601 substituted with Omega-N-methylated arginine" [UniProtKB:Q92793] comment: By similarity xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010955 name: CBP_HUMAN-Omega-N-methylated arginine625 def: "Protein CBP_HUMAN with the residue 625 substituted with Omega-N-methylated arginine" [UniProtKB:Q92793] comment: By similarity xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010956 name: CBP_HUMAN-Phosphothreonine1001 def: "Protein CBP_HUMAN with the residue 1001 substituted with Phosphothreonine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010957 name: CBP_HUMAN-Phosphoserine1030 def: "Protein CBP_HUMAN with the residue 1030 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010958 name: CBP_HUMAN-Phosphoserine1072 def: "Protein CBP_HUMAN with the residue 1072 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010959 name: CBP_HUMAN-N6-acetyllysine1588 def: "Protein CBP_HUMAN with the residue 1588 substituted with N6-acetyllysine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010960 name: CBP_HUMAN-N6-acetyllysine1591 def: "Protein CBP_HUMAN with the residue 1591 substituted with N6-acetyllysine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010961 name: CBP_HUMAN-N6-acetyllysine1592 def: "Protein CBP_HUMAN with the residue 1592 substituted with N6-acetyllysine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010962 name: CBP_HUMAN-N6-acetyllysine1595 def: "Protein CBP_HUMAN with the residue 1595 substituted with N6-acetyllysine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010963 name: CBP_HUMAN-N6-acetyllysine1597 def: "Protein CBP_HUMAN with the residue 1597 substituted with N6-acetyllysine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010964 name: CBP_HUMAN-Phosphoserine1755 def: "Protein CBP_HUMAN with the residue 1755 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0010965 name: CBX1_HUMAN-Phosphoserine89 def: "Protein CBX1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:P83916] xref: UniProtKB:P83916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000310 ! nuclear heterochromatin relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0006126 ! CBX1_HUMAN [Term] id: CCO:B0010966 name: CBX1_HUMAN-Phosphoserine175 def: "Protein CBX1_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:P83916] xref: UniProtKB:P83916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006126 ! CBX1_HUMAN [Term] id: CCO:B0010967 name: CBX5_HUMAN-Phosphothreonine8 def: "Protein CBX5_HUMAN with the residue 8 substituted with Phosphothreonine" [UniProtKB:P45973] xref: UniProtKB:P45973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:B0010968 name: CBX5_HUMAN-Phosphoserine11 def: "Protein CBX5_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P45973] xref: UniProtKB:P45973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:B0010969 name: CBX5_HUMAN-Phosphoserine12 def: "Protein CBX5_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:P45973] xref: UniProtKB:P45973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:B0010970 name: CBX5_HUMAN-Phosphoserine13 def: "Protein CBX5_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P45973] xref: UniProtKB:P45973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000310 ! nuclear heterochromatin relationship: located_in CCO:C0000730 ! chromocenter relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:B0010971 name: CBX5_HUMAN-Phosphoserine14 def: "Protein CBX5_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:P45973] xref: UniProtKB:P45973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:B0010972 name: CBX5_HUMAN-Phosphoserine92 def: "Protein CBX5_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:P45973] xref: UniProtKB:P45973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:B0010973 name: CBX5_HUMAN-Phosphoserine110 def: "Protein CBX5_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:P45973] xref: UniProtKB:P45973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:B0010974 name: CCAR1_HUMAN-Phosphoserine214 def: "Protein CCAR1_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q8IX12] xref: UniProtKB:Q8IX12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001950 ! CCAR1_HUMAN [Term] id: CCO:B0010975 name: CCAR1_HUMAN-Phosphoserine329 def: "Protein CCAR1_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q8IX12] xref: UniProtKB:Q8IX12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001950 ! CCAR1_HUMAN [Term] id: CCO:B0010976 name: CCAR1_HUMAN-Phosphoserine333 def: "Protein CCAR1_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q8IX12] xref: UniProtKB:Q8IX12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001950 ! CCAR1_HUMAN [Term] id: CCO:B0010977 name: CCAR1_HUMAN-Phosphoserine339 def: "Protein CCAR1_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:Q8IX12] xref: UniProtKB:Q8IX12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001950 ! CCAR1_HUMAN [Term] id: CCO:B0010978 name: CCAR1_HUMAN-Phosphoserine343 def: "Protein CCAR1_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:Q8IX12] xref: UniProtKB:Q8IX12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001950 ! CCAR1_HUMAN [Term] id: CCO:B0010979 name: CCAR1_HUMAN-Phosphoserine1149 def: "Protein CCAR1_HUMAN with the residue 1149 substituted with Phosphoserine" [UniProtKB:Q8IX12] xref: UniProtKB:Q8IX12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001950 ! CCAR1_HUMAN [Term] id: CCO:B0010983 name: CCD99_HUMAN-Phosphotyrosine279 def: "Protein CCD99_HUMAN with the residue 279 substituted with Phosphotyrosine" [UniProtKB:Q96EA4] comment: By similarity xref: UniProtKB:Q96EA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006191 ! CCD99_HUMAN [Term] id: CCO:B0010984 name: CCD99_HUMAN-Phosphothreonine487 def: "Protein CCD99_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:Q96EA4] xref: UniProtKB:Q96EA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006191 ! CCD99_HUMAN [Term] id: CCO:B0010985 name: CCD99_HUMAN-Phosphoserine515 def: "Protein CCD99_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:Q96EA4] xref: UniProtKB:Q96EA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006191 ! CCD99_HUMAN [Term] id: CCO:B0010986 name: CCD99_HUMAN-Phosphoserine555 def: "Protein CCD99_HUMAN with the residue 555 substituted with Phosphoserine" [UniProtKB:Q96EA4] xref: UniProtKB:Q96EA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006191 ! CCD99_HUMAN [Term] id: CCO:B0010992 name: CCNE1_HUMAN-Phosphoserine59 def: "Protein CCNE1_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:P24864] xref: UniProtKB:P24864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001554 ! CCNE1_HUMAN [Term] id: CCO:B0010993 name: CCNE1_HUMAN-Phosphothreonine77 def: "Protein CCNE1_HUMAN with the residue 77 substituted with Phosphothreonine" [UniProtKB:P24864] xref: UniProtKB:P24864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001554 ! CCNE1_HUMAN [Term] id: CCO:B0010994 name: CCNE1_HUMAN-Phosphoserine387 def: "Protein CCNE1_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:P24864] xref: UniProtKB:P24864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001554 ! CCNE1_HUMAN [Term] id: CCO:B0010995 name: CCNE1_HUMAN-Phosphothreonine395 def: "Protein CCNE1_HUMAN with the residue 395 substituted with Phosphothreonine" [UniProtKB:P24864] comment: by GSK3; xref: UniProtKB:P24864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001554 ! CCNE1_HUMAN [Term] id: CCO:B0010996 name: CCNE1_HUMAN-Phosphoserine399 def: "Protein CCNE1_HUMAN with the residue 399 substituted with Phosphoserine" [UniProtKB:P24864] comment: by CDK2; xref: UniProtKB:P24864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001554 ! CCNE1_HUMAN [Term] id: CCO:B0010997 name: CCNE2_HUMAN-Phosphothreonine392 def: "Protein CCNE2_HUMAN with the residue 392 substituted with Phosphothreonine" [UniProtKB:O96020] comment: Probable xref: UniProtKB:O96020 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001460 ! CCNE2_HUMAN [Term] id: CCO:B0010998 name: CCNH_HUMAN-Phosphoserine5 def: "Protein CCNH_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:P51946] comment: by CDK8; xref: UniProtKB:P51946 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001652 ! CCNH_HUMAN [Term] id: CCO:B0010999 name: CCNH_HUMAN-Phosphoserine304 def: "Protein CCNH_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:P51946] comment: by CDK8; xref: UniProtKB:P51946 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001652 ! CCNH_HUMAN [Term] id: CCO:B0011000 name: CCNH_HUMAN-Phosphothreonine315 def: "Protein CCNH_HUMAN with the residue 315 substituted with Phosphothreonine" [UniProtKB:P51946] xref: UniProtKB:P51946 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000901 ! cyclin-dependent protein kinase activating kinase holoenzyme complex relationship: transformation_of CCO:B0001652 ! CCNH_HUMAN [Term] id: CCO:B0011001 name: CCNK_HUMAN-Phosphoserine324 def: "Protein CCNK_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:O75909] xref: UniProtKB:O75909 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001439 ! CCNK_HUMAN [Term] id: CCO:B0011002 name: CCNK_HUMAN-Phosphoserine329 def: "Protein CCNK_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:O75909] xref: UniProtKB:O75909 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001439 ! CCNK_HUMAN [Term] id: CCO:B0011003 name: CCNK_HUMAN-Phosphoserine340 def: "Protein CCNK_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:O75909] xref: UniProtKB:O75909 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001439 ! CCNK_HUMAN [Term] id: CCO:B0011004 name: CCNL1_HUMAN-Phosphoserine65 def: "Protein CCNL1_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q9UK58] xref: UniProtKB:Q9UK58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0002218 ! CCNL1_HUMAN [Term] id: CCO:B0011005 name: CCNL1_HUMAN-Phosphoserine355 def: "Protein CCNL1_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q9UK58] xref: UniProtKB:Q9UK58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002218 ! CCNL1_HUMAN [Term] id: CCO:B0011006 name: CCNT1_HUMAN-N6-acetyllysine492 def: "Protein CCNT1_HUMAN with the residue 492 substituted with N6-acetyllysine" [UniProtKB:O60563] xref: UniProtKB:O60563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001410 ! CCNT1_HUMAN [Term] id: CCO:B0011007 name: CCNT2_HUMAN-Phosphoserine480 def: "Protein CCNT2_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:O60583] xref: UniProtKB:O60583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001412 ! CCNT2_HUMAN [Term] id: CCO:B0011011 name: CCPG1_HUMAN-Phosphothreonine99 def: "Protein CCPG1_HUMAN with the residue 99 substituted with Phosphothreonine" [UniProtKB:Q9ULG6] xref: UniProtKB:Q9ULG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0002225 ! CCPG1_HUMAN [Term] id: CCO:B0011012 name: CCPG1_HUMAN-Phosphoserine101 def: "Protein CCPG1_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q9ULG6] xref: UniProtKB:Q9ULG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002225 ! CCPG1_HUMAN [Term] id: CCO:B0011013 name: CCPG1_HUMAN-Phosphoserine104 def: "Protein CCPG1_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:Q9ULG6] xref: UniProtKB:Q9ULG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002225 ! CCPG1_HUMAN [Term] id: CCO:B0011014 name: CD28_HUMAN-Phosphotyrosine191 def: "Protein CD28_HUMAN with the residue 191 substituted with Phosphotyrosine" [UniProtKB:P10747] xref: UniProtKB:P10747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001508 ! CD28_HUMAN [Term] id: CCO:B0011015 name: CD28_HUMAN-Phosphotyrosine209 def: "Protein CD28_HUMAN with the residue 209 substituted with Phosphotyrosine" [UniProtKB:P10747] xref: UniProtKB:P10747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001508 ! CD28_HUMAN [Term] id: CCO:B0011016 name: CD2AP_HUMAN-Phosphotyrosine88 def: "Protein CD2AP_HUMAN with the residue 88 substituted with Phosphotyrosine" [UniProtKB:Q9Y5K6] xref: UniProtKB:Q9Y5K6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002257 ! CD2AP_HUMAN [Term] id: CCO:B0011017 name: CD2AP_HUMAN-Phosphoserine510 def: "Protein CD2AP_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q9Y5K6] xref: UniProtKB:Q9Y5K6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002257 ! CD2AP_HUMAN [Term] id: CCO:B0011018 name: CD2L1_HUMAN-Phosphoserine283 def: "Protein CD2L1_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:P21127] xref: UniProtKB:P21127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001540 ! CD2L1_HUMAN [Term] id: CCO:B0011019 name: CD2L1_HUMAN-Phosphothreonine448 def: "Protein CD2L1_HUMAN with the residue 448 substituted with Phosphothreonine" [UniProtKB:P21127] comment: By similarity xref: UniProtKB:P21127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001540 ! CD2L1_HUMAN [Term] id: CCO:B0011020 name: CD2L1_HUMAN-Phosphotyrosine449 def: "Protein CD2L1_HUMAN with the residue 449 substituted with Phosphotyrosine" [UniProtKB:P21127] comment: By similarity xref: UniProtKB:P21127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001540 ! CD2L1_HUMAN [Term] id: CCO:B0011021 name: CD2L1_HUMAN-Phosphoserine589 def: "Protein CD2L1_HUMAN with the residue 589 substituted with Phosphoserine" [UniProtKB:P21127] xref: UniProtKB:P21127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001540 ! CD2L1_HUMAN [Term] id: CCO:B0011022 name: CD2L1_HUMAN-Phosphothreonine595 def: "Protein CD2L1_HUMAN with the residue 595 substituted with Phosphothreonine" [UniProtKB:P21127] xref: UniProtKB:P21127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001540 ! CD2L1_HUMAN [Term] id: CCO:B0011023 name: CD2L1_HUMAN-Phosphothreonine751 def: "Protein CD2L1_HUMAN with the residue 751 substituted with Phosphothreonine" [UniProtKB:P21127] comment: By similarity xref: UniProtKB:P21127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001540 ! CD2L1_HUMAN [Term] id: CCO:B0011024 name: CD2L1_HUMAN-Phosphoserine752 def: "Protein CD2L1_HUMAN with the residue 752 substituted with Phosphoserine" [UniProtKB:P21127] comment: By similarity xref: UniProtKB:P21127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001540 ! CD2L1_HUMAN [Term] id: CCO:B0011025 name: CD2L2_HUMAN-Phosphoserine222 def: "Protein CD2L2_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0011026 name: CD2L2_HUMAN-Phosphoserine271 def: "Protein CD2L2_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0011027 name: CD2L2_HUMAN-Phosphothreonine433 def: "Protein CD2L2_HUMAN with the residue 433 substituted with Phosphothreonine" [UniProtKB:Q9UQ88] comment: By similarity xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0011028 name: CD2L2_HUMAN-Phosphotyrosine434 def: "Protein CD2L2_HUMAN with the residue 434 substituted with Phosphotyrosine" [UniProtKB:Q9UQ88] comment: By similarity xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0011029 name: CD2L2_HUMAN-Phosphothreonine580 def: "Protein CD2L2_HUMAN with the residue 580 substituted with Phosphothreonine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0011030 name: CD2L2_HUMAN-Phosphothreonine736 def: "Protein CD2L2_HUMAN with the residue 736 substituted with Phosphothreonine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0011031 name: CD2L2_HUMAN-Phosphoserine737 def: "Protein CD2L2_HUMAN with the residue 737 substituted with Phosphoserine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0011032 name: CD2L5_HUMAN-Phosphoserine315 def: "Protein CD2L5_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011033 name: CD2L5_HUMAN-Phosphoserine317 def: "Protein CD2L5_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011034 name: CD2L5_HUMAN-Phosphoserine325 def: "Protein CD2L5_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011035 name: CD2L5_HUMAN-Phosphoserine340 def: "Protein CD2L5_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011036 name: CD2L5_HUMAN-Phosphoserine342 def: "Protein CD2L5_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011037 name: CD2L5_HUMAN-Phosphoserine367 def: "Protein CD2L5_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011038 name: CD2L5_HUMAN-Phosphoserine383 def: "Protein CD2L5_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011039 name: CD2L5_HUMAN-Phosphoserine395 def: "Protein CD2L5_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011040 name: CD2L5_HUMAN-Phosphoserine397 def: "Protein CD2L5_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011041 name: CD2L5_HUMAN-Phosphoserine400 def: "Protein CD2L5_HUMAN with the residue 400 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011042 name: CD2L5_HUMAN-Phosphoserine436 def: "Protein CD2L5_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q14004] comment: By similarity xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011043 name: CD2L5_HUMAN-Phosphoserine437 def: "Protein CD2L5_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011044 name: CD2L5_HUMAN-Phosphoserine439 def: "Protein CD2L5_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011045 name: CD2L5_HUMAN-Phosphoserine441 def: "Protein CD2L5_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011046 name: CD2L5_HUMAN-Phosphothreonine442 def: "Protein CD2L5_HUMAN with the residue 442 substituted with Phosphothreonine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011047 name: CD2L5_HUMAN-Phosphoserine1066 def: "Protein CD2L5_HUMAN with the residue 1066 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011048 name: CD2L5_HUMAN-Phosphothreonine1246 def: "Protein CD2L5_HUMAN with the residue 1246 substituted with Phosphothreonine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0011049 name: CD45_HUMAN-Phosphoserine995 def: "Protein CD45_HUMAN with the residue 995 substituted with Phosphoserine" [UniProtKB:P08575] xref: UniProtKB:P08575 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001499 ! CD45_HUMAN [Term] id: CCO:B0011050 name: CD45_HUMAN-Phosphoserine1003 def: "Protein CD45_HUMAN with the residue 1003 substituted with Phosphoserine" [UniProtKB:P08575] xref: UniProtKB:P08575 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001499 ! CD45_HUMAN [Term] id: CCO:B0011051 name: CD45_HUMAN-Phosphoserine1007 def: "Protein CD45_HUMAN with the residue 1007 substituted with Phosphoserine" [UniProtKB:P08575] xref: UniProtKB:P08575 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001499 ! CD45_HUMAN [Term] id: CCO:B0011052 name: CDC16_HUMAN-Phosphoserine112 def: "Protein CDC16_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:Q13042] xref: UniProtKB:Q13042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001739 ! CDC16_HUMAN [Term] id: CCO:B0011053 name: CDC16_HUMAN-Phosphoserine490 def: "Protein CDC16_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:Q13042] xref: UniProtKB:Q13042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001739 ! CDC16_HUMAN [Term] id: CCO:B0011054 name: CDC16_HUMAN-Phosphoserine560 def: "Protein CDC16_HUMAN with the residue 560 substituted with Phosphoserine" [UniProtKB:Q13042] xref: UniProtKB:Q13042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000436 ! spindle microtubule relationship: transformation_of CCO:B0001739 ! CDC16_HUMAN [Term] id: CCO:B0011055 name: CDC16_HUMAN-Phosphothreonine581 def: "Protein CDC16_HUMAN with the residue 581 substituted with Phosphothreonine" [UniProtKB:Q13042] xref: UniProtKB:Q13042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001739 ! CDC16_HUMAN [Term] id: CCO:B0011056 name: CDC16_HUMAN-Phosphoserine595 def: "Protein CDC16_HUMAN with the residue 595 substituted with Phosphoserine" [UniProtKB:Q13042] xref: UniProtKB:Q13042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001739 ! CDC16_HUMAN [Term] id: CCO:B0011057 name: CDC16_HUMAN-Phosphothreonine599 def: "Protein CDC16_HUMAN with the residue 599 substituted with Phosphothreonine" [UniProtKB:Q13042] xref: UniProtKB:Q13042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001739 ! CDC16_HUMAN [Term] id: CCO:B0011058 name: CDC20_HUMAN-Phosphothreonine70 def: "Protein CDC20_HUMAN with the residue 70 substituted with Phosphothreonine" [UniProtKB:Q12834] xref: UniProtKB:Q12834 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001733 ! CDC20_HUMAN [Term] id: CCO:B0011059 name: CDC20_HUMAN-Phosphothreonine106 def: "Protein CDC20_HUMAN with the residue 106 substituted with Phosphothreonine" [UniProtKB:Q12834] xref: UniProtKB:Q12834 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001733 ! CDC20_HUMAN [Term] id: CCO:B0011060 name: CDC23_HUMAN-Phosphotyrosine267 def: "Protein CDC23_HUMAN with the residue 267 substituted with Phosphotyrosine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0011061 name: CDC23_HUMAN-Phosphothreonine556 def: "Protein CDC23_HUMAN with the residue 556 substituted with Phosphothreonine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0011062 name: CDC23_HUMAN-Phosphothreonine559 def: "Protein CDC23_HUMAN with the residue 559 substituted with Phosphothreonine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0011063 name: CDC23_HUMAN-Phosphoserine572 def: "Protein CDC23_HUMAN with the residue 572 substituted with Phosphoserine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0011064 name: CDC23_HUMAN-Phosphoserine582 def: "Protein CDC23_HUMAN with the residue 582 substituted with Phosphoserine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0011065 name: CDC23_HUMAN-Phosphothreonine590 def: "Protein CDC23_HUMAN with the residue 590 substituted with Phosphothreonine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0011066 name: CDC26_HUMAN-Phosphoserine78 def: "Protein CDC26_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:Q8NHZ8] xref: UniProtKB:Q8NHZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001986 ! CDC26_HUMAN [Term] id: CCO:B0011067 name: CDC26_HUMAN-Phosphoserine82 def: "Protein CDC26_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q8NHZ8] xref: UniProtKB:Q8NHZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001986 ! CDC26_HUMAN [Term] id: CCO:B0011068 name: CDC27_HUMAN-Phosphothreonine205 def: "Protein CDC27_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011069 name: CDC27_HUMAN-Phosphothreonine209 def: "Protein CDC27_HUMAN with the residue 209 substituted with Phosphothreonine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000436 ! spindle microtubule relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011070 name: CDC27_HUMAN-Phosphothreonine244 def: "Protein CDC27_HUMAN with the residue 244 substituted with Phosphothreonine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011071 name: CDC27_HUMAN-Phosphoserine291 def: "Protein CDC27_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011072 name: CDC27_HUMAN-Phosphothreonine313 def: "Protein CDC27_HUMAN with the residue 313 substituted with Phosphothreonine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011073 name: CDC27_HUMAN-Phosphoserine426 def: "Protein CDC27_HUMAN with the residue 426 substituted with Phosphoserine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011074 name: CDC27_HUMAN-Phosphothreonine430 def: "Protein CDC27_HUMAN with the residue 430 substituted with Phosphothreonine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011075 name: CDC27_HUMAN-Phosphoserine435 def: "Protein CDC27_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011076 name: CDC27_HUMAN-Phosphoserine438 def: "Protein CDC27_HUMAN with the residue 438 substituted with Phosphoserine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011077 name: CDC27_HUMAN-Phosphothreonine446 def: "Protein CDC27_HUMAN with the residue 446 substituted with Phosphothreonine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0011078 name: CDC2_HUMAN-Phosphothreonine14 def: "Protein CDC2_HUMAN with the residue 14 substituted with Phosphothreonine" [UniProtKB:P06493] xref: UniProtKB:P06493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001846 ! RNA polymerase subunit kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000436 ! spindle microtubule relationship: located_in CCO:C0001017 ! midbody relationship: transformation_of CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:B0011079 name: CDC2_HUMAN-Phosphotyrosine15 def: "Protein CDC2_HUMAN with the residue 15 substituted with Phosphotyrosine" [UniProtKB:P06493] xref: UniProtKB:P06493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:B0011080 name: CDC2_HUMAN-Phosphotyrosine19 def: "Protein CDC2_HUMAN with the residue 19 substituted with Phosphotyrosine" [UniProtKB:P06493] xref: UniProtKB:P06493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:B0011081 name: CDC2_HUMAN-Phosphothreonine161 def: "Protein CDC2_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:P06493] xref: UniProtKB:P06493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:B0011082 name: CDC37_HUMAN-Phosphotyrosine298 def: "Protein CDC37_HUMAN with the residue 298 substituted with Phosphotyrosine" [UniProtKB:Q16543] xref: UniProtKB:Q16543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_function CCO:F0008202 ! Hsp90 protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001819 ! CDC37_HUMAN [Term] id: CCO:B0011083 name: CDC42_HUMAN-Cysteine methyl ester188 def: "Protein CDC42_HUMAN with the residue 188 substituted with Cysteine methyl ester" [UniProtKB:P60953] xref: UniProtKB:P60953 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:B0011084 name: CDC5L_HUMAN-Phosphoserine303 def: "Protein CDC5L_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0011085 name: CDC5L_HUMAN-Phosphothreonine385 def: "Protein CDC5L_HUMAN with the residue 385 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0011086 name: CDC5L_HUMAN-Phosphothreonine396 def: "Protein CDC5L_HUMAN with the residue 396 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0011087 name: CDC6_HUMAN-Phosphothreonine166 def: "Protein CDC6_HUMAN with the residue 166 substituted with Phosphothreonine" [UniProtKB:Q99741] xref: UniProtKB:Q99741 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:B0011088 name: CDCA2_HUMAN-Phosphoserine99 def: "Protein CDCA2_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0011089 name: CDCA2_HUMAN-Phosphoserine292 def: "Protein CDCA2_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0011090 name: CDCA2_HUMAN-Phosphoserine336 def: "Protein CDCA2_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0011091 name: CDCA2_HUMAN-Phosphoserine401 def: "Protein CDCA2_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0011092 name: CDCA3_HUMAN-Phosphoserine68 def: "Protein CDCA3_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0011093 name: CDCA3_HUMAN-Phosphothreonine159 def: "Protein CDCA3_HUMAN with the residue 159 substituted with Phosphothreonine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0011094 name: CDCA3_HUMAN-Phosphoserine165 def: "Protein CDCA3_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0011095 name: CDCA3_HUMAN-Phosphothreonine177 def: "Protein CDCA3_HUMAN with the residue 177 substituted with Phosphothreonine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0011096 name: CDCA3_HUMAN-Phosphoserine199 def: "Protein CDCA3_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0011097 name: CDCA3_HUMAN-Phosphoserine209 def: "Protein CDCA3_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0011098 name: CDCA5_HUMAN-Phosphothreonine48 def: "Protein CDCA5_HUMAN with the residue 48 substituted with Phosphothreonine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0011099 name: CDCA5_HUMAN-Phosphoserine50 def: "Protein CDCA5_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0011100 name: CDCA5_HUMAN-Phosphoserine75 def: "Protein CDCA5_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0011101 name: CDCA5_HUMAN-Phosphoserine79 def: "Protein CDCA5_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0011102 name: CDK10_HUMAN-Phosphothreonine196 def: "Protein CDK10_HUMAN with the residue 196 substituted with Phosphothreonine" [UniProtKB:Q15131] xref: UniProtKB:Q15131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001803 ! CDK10_HUMAN [Term] id: CCO:B0011103 name: CDK2_HUMAN-Phosphothreonine14 def: "Protein CDK2_HUMAN with the residue 14 substituted with Phosphothreonine" [UniProtKB:P24941] xref: UniProtKB:P24941 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:B0011104 name: CDK2_HUMAN-Phosphotyrosine15 def: "Protein CDK2_HUMAN with the residue 15 substituted with Phosphotyrosine" [UniProtKB:P24941] comment: by WEE1; xref: UniProtKB:P24941 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:B0011105 name: CDK2_HUMAN-Phosphotyrosine19 def: "Protein CDK2_HUMAN with the residue 19 substituted with Phosphotyrosine" [UniProtKB:P24941] xref: UniProtKB:P24941 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005564 ! histone kinase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:B0011106 name: CDK2_HUMAN-Phosphothreonine160 def: "Protein CDK2_HUMAN with the residue 160 substituted with Phosphothreonine" [UniProtKB:P24941] comment: by CAK and CCRK; xref: UniProtKB:P24941 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:B0011107 name: CDK3_HUMAN-Phosphothreonine14 def: "Protein CDK3_HUMAN with the residue 14 substituted with Phosphothreonine" [UniProtKB:Q00526] xref: UniProtKB:Q00526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001707 ! CDK3_HUMAN [Term] id: CCO:B0011108 name: CDK3_HUMAN-Phosphotyrosine15 def: "Protein CDK3_HUMAN with the residue 15 substituted with Phosphotyrosine" [UniProtKB:Q00526] xref: UniProtKB:Q00526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001707 ! CDK3_HUMAN [Term] id: CCO:B0011109 name: CDK3_HUMAN-Phosphotyrosine19 def: "Protein CDK3_HUMAN with the residue 19 substituted with Phosphotyrosine" [UniProtKB:Q00526] xref: UniProtKB:Q00526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001707 ! CDK3_HUMAN [Term] id: CCO:B0011110 name: CDK3_HUMAN-Phosphothreonine160 def: "Protein CDK3_HUMAN with the residue 160 substituted with Phosphothreonine" [UniProtKB:Q00526] xref: UniProtKB:Q00526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001707 ! CDK3_HUMAN [Term] id: CCO:B0011111 name: CDK3_HUMAN-Phosphoserine207 def: "Protein CDK3_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:Q00526] xref: UniProtKB:Q00526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001707 ! CDK3_HUMAN [Term] id: CCO:B0011112 name: CDK4_HUMAN-Phosphothreonine172 def: "Protein CDK4_HUMAN with the residue 172 substituted with Phosphothreonine" [UniProtKB:P11802] comment: by CAK; By similarity xref: UniProtKB:P11802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001512 ! CDK4_HUMAN [Term] id: CCO:B0011113 name: CDK5_HUMAN-Phosphothreonine14 def: "Protein CDK5_HUMAN with the residue 14 substituted with Phosphothreonine" [UniProtKB:Q00535] comment: By similarity xref: UniProtKB:Q00535 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001709 ! CDK5_HUMAN [Term] id: CCO:B0011114 name: CDK5_HUMAN-Phosphotyrosine15 def: "Protein CDK5_HUMAN with the residue 15 substituted with Phosphotyrosine" [UniProtKB:Q00535] comment: by ABL1; xref: UniProtKB:Q00535 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001709 ! CDK5_HUMAN [Term] id: CCO:B0011115 name: CDK5_HUMAN-Phosphoserine159 def: "Protein CDK5_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:Q00535] comment: By similarity xref: UniProtKB:Q00535 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001477 ! ErbB-2 class receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004461 ! acetylcholine receptor activator activity relationship: has_function CCO:F0005796 ! ErbB-3 class receptor binding relationship: has_function CCO:F0007673 ! tau-protein kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001300 ! neuromuscular junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0001709 ! CDK5_HUMAN [Term] id: CCO:B0011116 name: CDK6_HUMAN-Phosphotyrosine13 def: "Protein CDK6_HUMAN with the residue 13 substituted with Phosphotyrosine" [UniProtKB:Q00534] xref: UniProtKB:Q00534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:B0011117 name: CDK6_HUMAN-Phosphotyrosine24 def: "Protein CDK6_HUMAN with the residue 24 substituted with Phosphotyrosine" [UniProtKB:Q00534] xref: UniProtKB:Q00534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:B0011118 name: CDK7_HUMAN-Phosphoserine164 def: "Protein CDK7_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:P50613] xref: UniProtKB:P50613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001644 ! CDK7_HUMAN [Term] id: CCO:B0011119 name: CDK7_HUMAN-Phosphothreonine170 def: "Protein CDK7_HUMAN with the residue 170 substituted with Phosphothreonine" [UniProtKB:P50613] xref: UniProtKB:P50613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001846 ! RNA polymerase subunit kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001644 ! CDK7_HUMAN [Term] id: CCO:B0011120 name: CDK9_HUMAN-Phosphothreonine186 def: "Protein CDK9_HUMAN with the residue 186 substituted with Phosphothreonine" [UniProtKB:P50750] xref: UniProtKB:P50750 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001647 ! CDK9_HUMAN [Term] id: CCO:B0011121 name: CDN1A_HUMAN-N-acetylserine2 def: "Protein CDN1A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P38936] xref: UniProtKB:P38936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:B0011122 name: CDN1A_HUMAN-Phosphoserine130 def: "Protein CDN1A_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:P38936] xref: UniProtKB:P38936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:B0011123 name: CDN1A_HUMAN-Phosphothreonine145 def: "Protein CDN1A_HUMAN with the residue 145 substituted with Phosphothreonine" [UniProtKB:P38936] comment: by PKA and PKB/AKT1; xref: UniProtKB:P38936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:B0011124 name: CDN1A_HUMAN-Phosphoserine146 def: "Protein CDN1A_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:P38936] comment: by PKC; xref: UniProtKB:P38936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:B0011125 name: CDN1A_HUMAN-Phosphoserine160 def: "Protein CDN1A_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:P38936] comment: by PKC; in vitro; xref: UniProtKB:P38936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:B0011126 name: CDN1B_HUMAN-Phosphoserine10 def: "Protein CDN1B_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P46527] comment: by UHMK1; xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001382 ! transforming growth factor beta receptor, cytoplasmic mediator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0011127 name: CDN1B_HUMAN-Phosphoserine140 def: "Protein CDN1B_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P46527] xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0011128 name: CDN2D_HUMAN-N-acetylmethionine1 def: "Protein CDN2D_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P55273] xref: UniProtKB:P55273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001675 ! CDN2D_HUMAN [Term] id: CCO:B0011129 name: CDT1_HUMAN-Phosphoserine318 def: "Protein CDT1_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q9H211] xref: UniProtKB:Q9H211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000265 ! replication fork relationship: transformation_of CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:B0011130 name: CE110_HUMAN-Phosphoserine641 def: "Protein CE110_HUMAN with the residue 641 substituted with Phosphoserine" [UniProtKB:O43303] xref: UniProtKB:O43303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0001389 ! CE110_HUMAN [Term] id: CCO:B0011131 name: CELF1_HUMAN-Phosphoserine302 def: "Protein CELF1_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:Q92879] comment: By similarity xref: UniProtKB:Q92879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000118 ! translation repressor activity, nucleic acid binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0005722 ! BRE binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0006265 ! CELF1_HUMAN [Term] id: CCO:B0011132 name: CELR3_HUMAN-3-hydroxyaspartate1963 def: "Protein CELR3_HUMAN with the residue 1963 substituted with 3-hydroxyaspartate" [UniProtKB:Q9NYQ7] comment: Potential xref: UniProtKB:Q9NYQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005546 ! CELR3_HUMAN [Term] id: CCO:B0011133 name: CEND2_HUMAN-Phosphothreonine114 def: "Protein CEND2_HUMAN with the residue 114 substituted with Phosphothreonine" [UniProtKB:Q96P48] xref: UniProtKB:Q96P48 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002052 ! CEND2_HUMAN [Term] id: CCO:B0011134 name: CEND2_HUMAN-Phosphotyrosine497 def: "Protein CEND2_HUMAN with the residue 497 substituted with Phosphotyrosine" [UniProtKB:Q96P48] xref: UniProtKB:Q96P48 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002052 ! CEND2_HUMAN [Term] id: CCO:B0011135 name: CENPB_HUMAN-Phosphoserine156 def: "Protein CENPB_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:P07199] xref: UniProtKB:P07199 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005431 ! CENPB_HUMAN [Term] id: CCO:B0011136 name: CENPB_HUMAN-Phosphoserine165 def: "Protein CENPB_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:P07199] xref: UniProtKB:P07199 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005431 ! CENPB_HUMAN [Term] id: CCO:B0011137 name: CENPC_HUMAN-Phosphothreonine167 def: "Protein CENPC_HUMAN with the residue 167 substituted with Phosphothreonine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011138 name: CENPC_HUMAN-Phosphoserine170 def: "Protein CENPC_HUMAN with the residue 170 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011139 name: CENPC_HUMAN-Phosphoserine177 def: "Protein CENPC_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011140 name: CENPC_HUMAN-Phosphoserine225 def: "Protein CENPC_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011141 name: CENPC_HUMAN-Phosphoserine316 def: "Protein CENPC_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011142 name: CENPC_HUMAN-Phosphoserine333 def: "Protein CENPC_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011143 name: CENPC_HUMAN-Phosphoserine520 def: "Protein CENPC_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011144 name: CENPC_HUMAN-Phosphoserine524 def: "Protein CENPC_HUMAN with the residue 524 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011145 name: CENPC_HUMAN-Phosphoserine538 def: "Protein CENPC_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0011146 name: CENPE_HUMAN-Phosphothreonine422 def: "Protein CENPE_HUMAN with the residue 422 substituted with Phosphothreonine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011147 name: CENPE_HUMAN-Phosphoserine454 def: "Protein CENPE_HUMAN with the residue 454 substituted with Phosphoserine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011148 name: CENPE_HUMAN-Phosphothreonine544 def: "Protein CENPE_HUMAN with the residue 544 substituted with Phosphothreonine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005864 ! kinetochore binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000159 ! outer kinetochore of condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011149 name: CENPE_HUMAN-Phosphoserine611 def: "Protein CENPE_HUMAN with the residue 611 substituted with Phosphoserine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011150 name: CENPE_HUMAN-Phosphoserine1211 def: "Protein CENPE_HUMAN with the residue 1211 substituted with Phosphoserine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011151 name: CENPE_HUMAN-Phosphothreonine1268 def: "Protein CENPE_HUMAN with the residue 1268 substituted with Phosphothreonine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011152 name: CENPE_HUMAN-Phosphoserine2639 def: "Protein CENPE_HUMAN with the residue 2639 substituted with Phosphoserine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011153 name: CENPE_HUMAN-Phosphoserine2651 def: "Protein CENPE_HUMAN with the residue 2651 substituted with Phosphoserine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011154 name: CENPE_HUMAN-Phosphoserine2654 def: "Protein CENPE_HUMAN with the residue 2654 substituted with Phosphoserine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0011155 name: CENPF_HUMAN-Phosphoserine268 def: "Protein CENPF_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011156 name: CENPF_HUMAN-Phosphoserine274 def: "Protein CENPF_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011157 name: CENPF_HUMAN-Phosphoserine276 def: "Protein CENPF_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011158 name: CENPF_HUMAN-Phosphoserine821 def: "Protein CENPF_HUMAN with the residue 821 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011159 name: CENPF_HUMAN-Phosphoserine1255 def: "Protein CENPF_HUMAN with the residue 1255 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011160 name: CENPF_HUMAN-Phosphoserine1282 def: "Protein CENPF_HUMAN with the residue 1282 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011161 name: CENPF_HUMAN-Phosphotyrosine1315 def: "Protein CENPF_HUMAN with the residue 1315 substituted with Phosphotyrosine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011162 name: CENPF_HUMAN-Phosphothreonine1319 def: "Protein CENPF_HUMAN with the residue 1319 substituted with Phosphothreonine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011163 name: CENPF_HUMAN-Phosphoserine1324 def: "Protein CENPF_HUMAN with the residue 1324 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006133 ! dynein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000159 ! outer kinetochore of condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011164 name: CENPF_HUMAN-Phosphoserine1747 def: "Protein CENPF_HUMAN with the residue 1747 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011165 name: CENPF_HUMAN-Phosphoserine1750 def: "Protein CENPF_HUMAN with the residue 1750 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011166 name: CENPF_HUMAN-Phosphoserine1988 def: "Protein CENPF_HUMAN with the residue 1988 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011167 name: CENPF_HUMAN-Phosphoserine2513 def: "Protein CENPF_HUMAN with the residue 2513 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011168 name: CENPF_HUMAN-Phosphoserine2638 def: "Protein CENPF_HUMAN with the residue 2638 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011169 name: CENPF_HUMAN-Phosphoserine2996 def: "Protein CENPF_HUMAN with the residue 2996 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011170 name: CENPF_HUMAN-Phosphoserine3007 def: "Protein CENPF_HUMAN with the residue 3007 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011171 name: CENPF_HUMAN-Phosphoserine3094 def: "Protein CENPF_HUMAN with the residue 3094 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011172 name: CENPF_HUMAN-Phosphoserine3119 def: "Protein CENPF_HUMAN with the residue 3119 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011173 name: CENPF_HUMAN-Phosphoserine3150 def: "Protein CENPF_HUMAN with the residue 3150 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011174 name: CENPF_HUMAN-Phosphoserine3175 def: "Protein CENPF_HUMAN with the residue 3175 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011175 name: CENPF_HUMAN-Phosphoserine3179 def: "Protein CENPF_HUMAN with the residue 3179 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0011176 name: CENPJ_HUMAN-Phosphoserine1109 def: "Protein CENPJ_HUMAN with the residue 1109 substituted with Phosphoserine" [UniProtKB:Q9HC77] xref: UniProtKB:Q9HC77 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005426 ! CENPJ_HUMAN [Term] id: CCO:B0011177 name: CENPR_HUMAN-Phosphoserine28 def: "Protein CENPR_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q13352] comment: Probable xref: UniProtKB:Q13352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:B0011178 name: CEP55_HUMAN-Phosphoserine425 def: "Protein CEP55_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:Q53EZ4] comment: by CDC2 and MAPK1; xref: UniProtKB:Q53EZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001837 ! CEP55_HUMAN [Term] id: CCO:B0011179 name: CEP55_HUMAN-Phosphoserine428 def: "Protein CEP55_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q53EZ4] comment: by CDC2 and MAPK1; xref: UniProtKB:Q53EZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001837 ! CEP55_HUMAN [Term] id: CCO:B0011180 name: CEP55_HUMAN-Phosphoserine436 def: "Protein CEP55_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q53EZ4] comment: by PLK1; xref: UniProtKB:Q53EZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001837 ! CEP55_HUMAN [Term] id: CCO:B0011181 name: CETN2_HUMAN-Phosphoserine20 def: "Protein CETN2_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P41208] xref: UniProtKB:P41208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001604 ! CETN2_HUMAN [Term] id: CCO:B0011182 name: CETN2_HUMAN-Phosphothreonine26 def: "Protein CETN2_HUMAN with the residue 26 substituted with Phosphothreonine" [UniProtKB:P41208] xref: UniProtKB:P41208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0001604 ! CETN2_HUMAN [Term] id: CCO:B0011183 name: CFTR_HUMAN-Phosphoserine660 def: "Protein CFTR_HUMAN with the residue 660 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011184 name: CFTR_HUMAN-Phosphoserine686 def: "Protein CFTR_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKC; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011185 name: CFTR_HUMAN-Phosphoserine700 def: "Protein CFTR_HUMAN with the residue 700 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011186 name: CFTR_HUMAN-Phosphoserine712 def: "Protein CFTR_HUMAN with the residue 712 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011187 name: CFTR_HUMAN-Phosphoserine737 def: "Protein CFTR_HUMAN with the residue 737 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011188 name: CFTR_HUMAN-Phosphoserine753 def: "Protein CFTR_HUMAN with the residue 753 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011189 name: CFTR_HUMAN-Phosphoserine768 def: "Protein CFTR_HUMAN with the residue 768 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011190 name: CFTR_HUMAN-Phosphoserine790 def: "Protein CFTR_HUMAN with the residue 790 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKC; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011191 name: CFTR_HUMAN-Phosphoserine795 def: "Protein CFTR_HUMAN with the residue 795 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011192 name: CFTR_HUMAN-Phosphoserine813 def: "Protein CFTR_HUMAN with the residue 813 substituted with Phosphoserine" [UniProtKB:P13569] comment: by PKA; xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0011193 name: CG025_HUMAN-Phosphoserine208 def: "Protein CG025_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q9BPX7] xref: UniProtKB:Q9BPX7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006330 ! CG025_HUMAN [Term] id: CCO:B0011194 name: CG025_HUMAN-Phosphoserine210 def: "Protein CG025_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:Q9BPX7] xref: UniProtKB:Q9BPX7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006330 ! CG025_HUMAN [Term] id: CCO:B0011195 name: CG025_HUMAN-Phosphoserine212 def: "Protein CG025_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q9BPX7] xref: UniProtKB:Q9BPX7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006330 ! CG025_HUMAN [Term] id: CCO:B0011196 name: CH10_HUMAN-N-acetylalanine2 def: "Protein CH10_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P61604] xref: UniProtKB:P61604 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006092 ! CH10_HUMAN [Term] id: CCO:B0011197 name: CH60_HUMAN-Phosphoserine70 def: "Protein CH60_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:P10809] xref: UniProtKB:P10809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000901 ! cyclin-dependent protein kinase activating kinase holoenzyme complex relationship: transformation_of CCO:B0005730 ! CH60_HUMAN [Term] id: CCO:B0011198 name: CH60_HUMAN-Phosphotyrosine223 def: "Protein CH60_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:P10809] comment: By similarity xref: UniProtKB:P10809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005730 ! CH60_HUMAN [Term] id: CCO:B0011199 name: CH60_HUMAN-Phosphotyrosine227 def: "Protein CH60_HUMAN with the residue 227 substituted with Phosphotyrosine" [UniProtKB:P10809] xref: UniProtKB:P10809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005730 ! CH60_HUMAN [Term] id: CCO:B0011200 name: CHD3_HUMAN-Phosphoserine324 def: "Protein CHD3_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0011201 name: CHD3_HUMAN-Phosphoserine713 def: "Protein CHD3_HUMAN with the residue 713 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0011202 name: CHD3_HUMAN-Phosphoserine1601 def: "Protein CHD3_HUMAN with the residue 1601 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0011203 name: CHD3_HUMAN-Phosphoserine1605 def: "Protein CHD3_HUMAN with the residue 1605 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0011204 name: CHD8_HUMAN-Phosphothreonine258 def: "Protein CHD8_HUMAN with the residue 258 substituted with Phosphothreonine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0011205 name: CHD8_HUMAN-Phosphothreonine1119 def: "Protein CHD8_HUMAN with the residue 1119 substituted with Phosphothreonine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0011206 name: CHD8_HUMAN-Phosphoserine1141 def: "Protein CHD8_HUMAN with the residue 1141 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0011207 name: CHD8_HUMAN-Phosphoserine1145 def: "Protein CHD8_HUMAN with the residue 1145 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0011208 name: CHD8_HUMAN-Phosphoserine1790 def: "Protein CHD8_HUMAN with the residue 1790 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0011209 name: CHD8_HUMAN-Phosphoserine1792 def: "Protein CHD8_HUMAN with the residue 1792 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0011210 name: CHFR_HUMAN-Phosphothreonine130 def: "Protein CHFR_HUMAN with the residue 130 substituted with Phosphothreonine" [UniProtKB:Q96EP1] comment: By similarity xref: UniProtKB:Q96EP1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002035 ! CHFR_HUMAN [Term] id: CCO:B0011211 name: CHFR_HUMAN-Phosphothreonine386 def: "Protein CHFR_HUMAN with the residue 386 substituted with Phosphothreonine" [UniProtKB:Q96EP1] comment: By similarity xref: UniProtKB:Q96EP1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002035 ! CHFR_HUMAN [Term] id: CCO:B0011212 name: CHK1_HUMAN-Phosphoserine280 def: "Protein CHK1_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:O14757] comment: by PKB/AKT1; By similarity xref: UniProtKB:O14757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001359 ! CHK1_HUMAN [Term] id: CCO:B0011213 name: CHK1_HUMAN-Phosphoserine296 def: "Protein CHK1_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:O14757] xref: UniProtKB:O14757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000265 ! replication fork relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001359 ! CHK1_HUMAN [Term] id: CCO:B0011214 name: CHK1_HUMAN-Phosphoserine308 def: "Protein CHK1_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:O14757] xref: UniProtKB:O14757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001359 ! CHK1_HUMAN [Term] id: CCO:B0011215 name: CHK1_HUMAN-Phosphoserine317 def: "Protein CHK1_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:O14757] comment: by ATM and ATR; xref: UniProtKB:O14757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001359 ! CHK1_HUMAN [Term] id: CCO:B0011216 name: CHK1_HUMAN-Phosphoserine345 def: "Protein CHK1_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:O14757] comment: by ATM and ATR; xref: UniProtKB:O14757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001359 ! CHK1_HUMAN [Term] id: CCO:B0011217 name: CHK2_HUMAN-Phosphothreonine68 def: "Protein CHK2_HUMAN with the residue 68 substituted with Phosphothreonine" [UniProtKB:O96017] comment: by MLTK; xref: UniProtKB:O96017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001459 ! CHK2_HUMAN [Term] id: CCO:B0011218 name: CHSS2_HUMAN-Phosphoserine126 def: "Protein CHSS2_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q8IZ52] xref: UniProtKB:Q8IZ52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006320 ! CHSS2_HUMAN [Term] id: CCO:B0011219 name: CHSS2_HUMAN-Phosphothreonine129 def: "Protein CHSS2_HUMAN with the residue 129 substituted with Phosphothreonine" [UniProtKB:Q8IZ52] xref: UniProtKB:Q8IZ52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006320 ! CHSS2_HUMAN [Term] id: CCO:B0011220 name: CI082_HUMAN-Phosphoserine203 def: "Protein CI082_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q9H8G2] xref: UniProtKB:Q9H8G2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006175 ! CI082_HUMAN [Term] id: CCO:B0011221 name: CI082_HUMAN-Phosphoserine221 def: "Protein CI082_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q9H8G2] xref: UniProtKB:Q9H8G2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006175 ! CI082_HUMAN [Term] id: CCO:B0011222 name: CI082_HUMAN-Phosphoserine312 def: "Protein CI082_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q9H8G2] xref: UniProtKB:Q9H8G2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006175 ! CI082_HUMAN [Term] id: CCO:B0011225 name: CJ119_HUMAN-Phosphoserine154 def: "Protein CJ119_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q9BTE3] xref: UniProtKB:Q9BTE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005262 ! CJ119_HUMAN [Term] id: CCO:B0011226 name: CJ119_HUMAN-Phosphothreonine160 def: "Protein CJ119_HUMAN with the residue 160 substituted with Phosphothreonine" [UniProtKB:Q9BTE3] xref: UniProtKB:Q9BTE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0005262 ! CJ119_HUMAN [Term] id: CCO:B0011227 name: CK5P2_HUMAN-Phosphotyrosine461 def: "Protein CK5P2_HUMAN with the residue 461 substituted with Phosphotyrosine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0005717 ! neuronal Cdc2-like kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011228 name: CK5P2_HUMAN-Phosphoserine466 def: "Protein CK5P2_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011229 name: CK5P2_HUMAN-Phosphoserine468 def: "Protein CK5P2_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011230 name: CK5P2_HUMAN-Phosphoserine815 def: "Protein CK5P2_HUMAN with the residue 815 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011231 name: CK5P2_HUMAN-Phosphoserine1074 def: "Protein CK5P2_HUMAN with the residue 1074 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011232 name: CK5P2_HUMAN-Phosphoserine1238 def: "Protein CK5P2_HUMAN with the residue 1238 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011233 name: CK5P2_HUMAN-Phosphoserine1548 def: "Protein CK5P2_HUMAN with the residue 1548 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011234 name: CK5P2_HUMAN-Phosphoserine1556 def: "Protein CK5P2_HUMAN with the residue 1556 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0011235 name: CKAP2_HUMAN-Phosphoserine534 def: "Protein CKAP2_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0011236 name: CKAP2_HUMAN-Phosphothreonine579 def: "Protein CKAP2_HUMAN with the residue 579 substituted with Phosphothreonine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0011237 name: CKAP2_HUMAN-Phosphothreonine582 def: "Protein CKAP2_HUMAN with the residue 582 substituted with Phosphothreonine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0011238 name: CKAP2_HUMAN-Phosphothreonine597 def: "Protein CKAP2_HUMAN with the residue 597 substituted with Phosphothreonine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0011239 name: CKAP2_HUMAN-Phosphoserine602 def: "Protein CKAP2_HUMAN with the residue 602 substituted with Phosphoserine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0011240 name: CKAP2_HUMAN-Phosphoserine614 def: "Protein CKAP2_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0011241 name: CKAP2_HUMAN-Phosphothreonine623 def: "Protein CKAP2_HUMAN with the residue 623 substituted with Phosphothreonine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0011242 name: CKAP4_HUMAN-Phosphoserine17 def: "Protein CKAP4_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q07065] xref: UniProtKB:Q07065 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005829 ! CKAP4_HUMAN [Term] id: CCO:B0011243 name: CKAP5_HUMAN-Phosphoserine816 def: "Protein CKAP5_HUMAN with the residue 816 substituted with Phosphoserine" [UniProtKB:Q14008] xref: UniProtKB:Q14008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000149 ! gamma-tubulin complex relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: transformation_of CCO:B0001772 ! CKAP5_HUMAN [Term] id: CCO:B0011244 name: CLAP1_HUMAN-Phosphoserine545 def: "Protein CLAP1_HUMAN with the residue 545 substituted with Phosphoserine" [UniProtKB:Q7Z460] comment: By similarity xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011245 name: CLAP1_HUMAN-Phosphoserine559 def: "Protein CLAP1_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011246 name: CLAP1_HUMAN-Phosphoserine568 def: "Protein CLAP1_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011247 name: CLAP1_HUMAN-Phosphoserine598 def: "Protein CLAP1_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q7Z460] comment: By similarity xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011248 name: CLAP1_HUMAN-Phosphoserine600 def: "Protein CLAP1_HUMAN with the residue 600 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011249 name: CLAP1_HUMAN-Phosphoserine609 def: "Protein CLAP1_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011250 name: CLAP1_HUMAN-Phosphoserine1196 def: "Protein CLAP1_HUMAN with the residue 1196 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011251 name: CLAP1_HUMAN-Phosphoserine1223 def: "Protein CLAP1_HUMAN with the residue 1223 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0011252 name: CLAP2_HUMAN-Phosphoserine326 def: "Protein CLAP2_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:O75122] xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001713 ! galactoside 2-alpha-L-fucosyltransferase activity relationship: has_function CCO:F0008033 ! microtubule plus-end binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000396 ! kinetochore microtubule relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000439 ! cytoplasmic microtubule relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011253 name: CLAP2_HUMAN-Phosphoserine327 def: "Protein CLAP2_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:O75122] xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011254 name: CLAP2_HUMAN-Phosphoserine330 def: "Protein CLAP2_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:O75122] xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011255 name: CLAP2_HUMAN-Phosphoserine507 def: "Protein CLAP2_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:O75122] comment: By similarity xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011256 name: CLAP2_HUMAN-Phosphoserine525 def: "Protein CLAP2_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:O75122] xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011257 name: CLAP2_HUMAN-Phosphoserine529 def: "Protein CLAP2_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:O75122] xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011258 name: CLAP2_HUMAN-Phosphoserine596 def: "Protein CLAP2_HUMAN with the residue 596 substituted with Phosphoserine" [UniProtKB:O75122] comment: By similarity xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011259 name: CLAP2_HUMAN-Phosphoserine994 def: "Protein CLAP2_HUMAN with the residue 994 substituted with Phosphoserine" [UniProtKB:O75122] xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0011260 name: CLH2_HUMAN-Phosphothreonine103 def: "Protein CLH2_HUMAN with the residue 103 substituted with Phosphothreonine" [UniProtKB:P53675] xref: UniProtKB:P53675 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000975 ! clathrin coat of trans-Golgi network vesicle relationship: located_in CCO:C0000977 ! clathrin coat of coated pit relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0005460 ! CLH2_HUMAN [Term] id: CCO:B0011261 name: CLIP1_HUMAN-Phosphothreonine182 def: "Protein CLIP1_HUMAN with the residue 182 substituted with Phosphothreonine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0011262 name: CLIP1_HUMAN-Phosphoserine195 def: "Protein CLIP1_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0011263 name: CLIP1_HUMAN-Phosphoserine200 def: "Protein CLIP1_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0011264 name: CLIP1_HUMAN-Phosphoserine204 def: "Protein CLIP1_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0011265 name: CLK1_HUMAN-Phosphothreonine138 def: "Protein CLK1_HUMAN with the residue 138 substituted with Phosphothreonine" [UniProtKB:P49759] xref: UniProtKB:P49759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001632 ! CLK1_HUMAN [Term] id: CCO:B0011266 name: CLK1_HUMAN-Phosphoserine140 def: "Protein CLK1_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P49759] xref: UniProtKB:P49759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001632 ! CLK1_HUMAN [Term] id: CCO:B0011267 name: CLSPN_HUMAN-Phosphoserine65 def: "Protein CLSPN_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011268 name: CLSPN_HUMAN-Phosphoserine67 def: "Protein CLSPN_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011269 name: CLSPN_HUMAN-Phosphoserine75 def: "Protein CLSPN_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011270 name: CLSPN_HUMAN-Phosphoserine762 def: "Protein CLSPN_HUMAN with the residue 762 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011271 name: CLSPN_HUMAN-Phosphoserine764 def: "Protein CLSPN_HUMAN with the residue 764 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011272 name: CLSPN_HUMAN-Phosphoserine833 def: "Protein CLSPN_HUMAN with the residue 833 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011273 name: CLSPN_HUMAN-Phosphoserine839 def: "Protein CLSPN_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011274 name: CLSPN_HUMAN-Phosphoserine846 def: "Protein CLSPN_HUMAN with the residue 846 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011275 name: CLSPN_HUMAN-Phosphoserine950 def: "Protein CLSPN_HUMAN with the residue 950 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011276 name: CLSPN_HUMAN-Phosphothreonine1287 def: "Protein CLSPN_HUMAN with the residue 1287 substituted with Phosphothreonine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011277 name: CLSPN_HUMAN-Phosphoserine1289 def: "Protein CLSPN_HUMAN with the residue 1289 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0011280 name: CND1_HUMAN-Phosphothreonine103 def: "Protein CND1_HUMAN with the residue 103 substituted with Phosphothreonine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011281 name: CND1_HUMAN-Phosphothreonine577 def: "Protein CND1_HUMAN with the residue 577 substituted with Phosphothreonine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011282 name: CND1_HUMAN-Phosphoserine585 def: "Protein CND1_HUMAN with the residue 585 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011283 name: CND1_HUMAN-Phosphoserine1310 def: "Protein CND1_HUMAN with the residue 1310 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011284 name: CND1_HUMAN-Phosphoserine1330 def: "Protein CND1_HUMAN with the residue 1330 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011285 name: CND1_HUMAN-Phosphothreonine1331 def: "Protein CND1_HUMAN with the residue 1331 substituted with Phosphothreonine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011286 name: CND1_HUMAN-Phosphoserine1333 def: "Protein CND1_HUMAN with the residue 1333 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011287 name: CND1_HUMAN-Phosphothreonine1339 def: "Protein CND1_HUMAN with the residue 1339 substituted with Phosphothreonine" [UniProtKB:Q15021] comment: by CDC2; By similarity xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011288 name: CND1_HUMAN-Phosphoserine1366 def: "Protein CND1_HUMAN with the residue 1366 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011289 name: CND1_HUMAN-Phosphoserine1367 def: "Protein CND1_HUMAN with the residue 1367 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011290 name: CND1_HUMAN-Phosphoserine1370 def: "Protein CND1_HUMAN with the residue 1370 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011291 name: CND1_HUMAN-Phosphoserine1371 def: "Protein CND1_HUMAN with the residue 1371 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011292 name: CND1_HUMAN-Phosphoserine1376 def: "Protein CND1_HUMAN with the residue 1376 substituted with Phosphoserine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000124 ! condensin core heterodimer relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001889 ! pronucleus relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011293 name: CND1_HUMAN-Phosphothreonine1384 def: "Protein CND1_HUMAN with the residue 1384 substituted with Phosphothreonine" [UniProtKB:Q15021] comment: by CDC2; By similarity xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011294 name: CND1_HUMAN-Phosphothreonine1388 def: "Protein CND1_HUMAN with the residue 1388 substituted with Phosphothreonine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011295 name: CND1_HUMAN-Phosphothreonine1389 def: "Protein CND1_HUMAN with the residue 1389 substituted with Phosphothreonine" [UniProtKB:Q15021] comment: by CDC2; By similarity xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0011296 name: CND2_HUMAN-Phosphothreonine49 def: "Protein CND2_HUMAN with the residue 49 substituted with Phosphothreonine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011297 name: CND2_HUMAN-Phosphoserine78 def: "Protein CND2_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011298 name: CND2_HUMAN-Phosphoserine81 def: "Protein CND2_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011299 name: CND2_HUMAN-Phosphoserine92 def: "Protein CND2_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011300 name: CND2_HUMAN-Phosphoserine96 def: "Protein CND2_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011301 name: CND2_HUMAN-Phosphoserine201 def: "Protein CND2_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011302 name: CND2_HUMAN-Phosphoserine335 def: "Protein CND2_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011303 name: CND2_HUMAN-Phosphothreonine605 def: "Protein CND2_HUMAN with the residue 605 substituted with Phosphothreonine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0011304 name: CND3_HUMAN-Phosphoserine390 def: "Protein CND3_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011305 name: CND3_HUMAN-Phosphothreonine463 def: "Protein CND3_HUMAN with the residue 463 substituted with Phosphothreonine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011306 name: CND3_HUMAN-Phosphoserine467 def: "Protein CND3_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011307 name: CND3_HUMAN-Phosphoserine674 def: "Protein CND3_HUMAN with the residue 674 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011308 name: CND3_HUMAN-Phosphoserine944 def: "Protein CND3_HUMAN with the residue 944 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011309 name: CND3_HUMAN-Phosphoserine959 def: "Protein CND3_HUMAN with the residue 959 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011310 name: CND3_HUMAN-Phosphoserine973 def: "Protein CND3_HUMAN with the residue 973 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011311 name: CND3_HUMAN-Phosphoserine975 def: "Protein CND3_HUMAN with the residue 975 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011312 name: CND3_HUMAN-Phosphoserine1015 def: "Protein CND3_HUMAN with the residue 1015 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0011313 name: CNDD3_HUMAN-Phosphoserine531 def: "Protein CNDD3_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0011314 name: CNDD3_HUMAN-Phosphotyrosine972 def: "Protein CNDD3_HUMAN with the residue 972 substituted with Phosphotyrosine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0011315 name: CNDD3_HUMAN-Phosphoserine1384 def: "Protein CNDD3_HUMAN with the residue 1384 substituted with Phosphoserine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0011316 name: CNDD3_HUMAN-Phosphoserine1393 def: "Protein CNDD3_HUMAN with the residue 1393 substituted with Phosphoserine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0011317 name: CNDG2_HUMAN-Phosphothreonine805 def: "Protein CNDG2_HUMAN with the residue 805 substituted with Phosphothreonine" [UniProtKB:Q86XI2] xref: UniProtKB:Q86XI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001943 ! CNDG2_HUMAN [Term] id: CCO:B0011318 name: CNDG2_HUMAN-Phosphothreonine1119 def: "Protein CNDG2_HUMAN with the residue 1119 substituted with Phosphothreonine" [UniProtKB:Q86XI2] xref: UniProtKB:Q86XI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001943 ! CNDG2_HUMAN [Term] id: CCO:B0011319 name: CNTRB_HUMAN-Phosphoserine781 def: "Protein CNTRB_HUMAN with the residue 781 substituted with Phosphoserine" [UniProtKB:Q8N137] xref: UniProtKB:Q8N137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000384 ! centriole relationship: transformation_of CCO:B0001961 ! CNTRB_HUMAN [Term] id: CCO:B0011336 name: COR1A_HUMAN-N-acetylserine2 def: "Protein COR1A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P31146] xref: UniProtKB:P31146 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001581 ! COR1A_HUMAN [Term] id: CCO:B0011337 name: COX6C_HUMAN-N6-acetyllysine60 def: "Protein COX6C_HUMAN with the residue 60 substituted with N6-acetyllysine" [UniProtKB:P09669] comment: By similarity xref: UniProtKB:P09669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000600 ! cytochrome-c oxidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0006181 ! COX6C_HUMAN [Term] id: CCO:B0011338 name: CPNS1_HUMAN-N-acetylmethionine1 def: "Protein CPNS1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P04632] xref: UniProtKB:P04632 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000667 ! calcium-dependent cysteine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006088 ! CPNS1_HUMAN [Term] id: CCO:B0011339 name: CR025_HUMAN-Phosphoserine39 def: "Protein CR025_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q96B23] xref: UniProtKB:Q96B23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005186 ! CR025_HUMAN [Term] id: CCO:B0011340 name: CR025_HUMAN-Phosphoserine66 def: "Protein CR025_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q96B23] xref: UniProtKB:Q96B23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005186 ! CR025_HUMAN [Term] id: CCO:B0011341 name: CR025_HUMAN-Phosphoserine69 def: "Protein CR025_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:Q96B23] xref: UniProtKB:Q96B23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005186 ! CR025_HUMAN [Term] id: CCO:B0011342 name: CR025_HUMAN-Phosphoserine327 def: "Protein CR025_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:Q96B23] xref: UniProtKB:Q96B23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005186 ! CR025_HUMAN [Term] id: CCO:B0011345 name: CREB1_HUMAN-Phosphoserine111 def: "Protein CREB1_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:P16220] xref: UniProtKB:P16220 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005681 ! CREB1_HUMAN [Term] id: CCO:B0011346 name: CREB1_HUMAN-Phosphothreonine119 def: "Protein CREB1_HUMAN with the residue 119 substituted with Phosphothreonine" [UniProtKB:P16220] xref: UniProtKB:P16220 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005681 ! CREB1_HUMAN [Term] id: CCO:B0011347 name: CREB1_HUMAN-Phosphoserine133 def: "Protein CREB1_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:P16220] comment: by CaMK1, CaMK2 and CaMK4; xref: UniProtKB:P16220 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005681 ! CREB1_HUMAN [Term] id: CCO:B0011348 name: CREB1_HUMAN-Phosphoserine142 def: "Protein CREB1_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:P16220] comment: by CaMK2; By similarity xref: UniProtKB:P16220 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0005681 ! CREB1_HUMAN [Term] id: CCO:B0011349 name: CROCC_HUMAN-Phosphoserine1619 def: "Protein CROCC_HUMAN with the residue 1619 substituted with Phosphoserine" [UniProtKB:Q5TZA2] xref: UniProtKB:Q5TZA2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0004206 ! kinesin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000384 ! centriole relationship: located_in CCO:C0001625 ! ciliary rootlet relationship: transformation_of CCO:B0001895 ! CROCC_HUMAN [Term] id: CCO:B0011350 name: CSK2B_HUMAN-Phosphoserine2 def: "Protein CSK2B_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P67870] comment: by autocatalysis; xref: UniProtKB:P67870 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:B0011351 name: CSK2B_HUMAN-Phosphoserine3 def: "Protein CSK2B_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:P67870] xref: UniProtKB:P67870 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001052 ! protein kinase CK2 activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002008 ! protein kinase CK2 regulator activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000505 ! protein kinase CK2 complex relationship: transformation_of CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:B0011352 name: CSK2B_HUMAN-Phosphoserine4 def: "Protein CSK2B_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:P67870] xref: UniProtKB:P67870 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:B0011353 name: CSK2B_HUMAN-Phosphoserine209 def: "Protein CSK2B_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:P67870] xref: UniProtKB:P67870 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:B0011354 name: CSK_HUMAN-Phosphotyrosine184 def: "Protein CSK_HUMAN with the residue 184 substituted with Phosphotyrosine" [UniProtKB:P41240] xref: UniProtKB:P41240 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001606 ! CSK_HUMAN [Term] id: CCO:B0011355 name: CSK_HUMAN-Phosphotyrosine304 def: "Protein CSK_HUMAN with the residue 304 substituted with Phosphotyrosine" [UniProtKB:P41240] comment: by autocatalysis; xref: UniProtKB:P41240 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001606 ! CSK_HUMAN [Term] id: CCO:B0011356 name: CSK_HUMAN-Phosphotyrosine416 def: "Protein CSK_HUMAN with the residue 416 substituted with Phosphotyrosine" [UniProtKB:P41240] comment: by autocatalysis; By similarity xref: UniProtKB:P41240 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001606 ! CSK_HUMAN [Term] id: CCO:B0011357 name: CSN1_HUMAN-Phosphoserine448 def: "Protein CSN1_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:Q13098] xref: UniProtKB:Q13098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001740 ! CSN1_HUMAN [Term] id: CCO:B0011358 name: CSN1_HUMAN-Phosphoserine454 def: "Protein CSN1_HUMAN with the residue 454 substituted with Phosphoserine" [UniProtKB:Q13098] xref: UniProtKB:Q13098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001740 ! CSN1_HUMAN [Term] id: CCO:B0011359 name: CSN1_HUMAN-Phosphothreonine459 def: "Protein CSN1_HUMAN with the residue 459 substituted with Phosphothreonine" [UniProtKB:Q13098] xref: UniProtKB:Q13098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001740 ! CSN1_HUMAN [Term] id: CCO:B0011360 name: CSN1_HUMAN-Phosphoserine463 def: "Protein CSN1_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:Q13098] xref: UniProtKB:Q13098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000530 ! signalosome relationship: transformation_of CCO:B0001740 ! CSN1_HUMAN [Term] id: CCO:B0011361 name: CSN1_HUMAN-Phosphoserine468 def: "Protein CSN1_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:Q13098] xref: UniProtKB:Q13098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001740 ! CSN1_HUMAN [Term] id: CCO:B0011362 name: CSN5_HUMAN-N-acetylalanine2 def: "Protein CSN5_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q92905] xref: UniProtKB:Q92905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: located_in CCO:C0000530 ! signalosome relationship: transformation_of CCO:B0002025 ! CSN5_HUMAN [Term] id: CCO:B0011363 name: CSN7A_HUMAN-Phosphoserine232 def: "Protein CSN7A_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q9UBW8] xref: UniProtKB:Q9UBW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006264 ! CSN7A_HUMAN [Term] id: CCO:B0011364 name: CTCF_HUMAN-Phosphoserine609 def: "Protein CTCF_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:P49711] xref: UniProtKB:P49711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001630 ! CTCF_HUMAN [Term] id: CCO:B0011365 name: CTCF_HUMAN-Phosphoserine610 def: "Protein CTCF_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:P49711] xref: UniProtKB:P49711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001630 ! CTCF_HUMAN [Term] id: CCO:B0011366 name: CTCF_HUMAN-Phosphoserine612 def: "Protein CTCF_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:P49711] xref: UniProtKB:P49711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001630 ! CTCF_HUMAN [Term] id: CCO:B0011367 name: CTNA1_HUMAN-Phosphoserine641 def: "Protein CTNA1_HUMAN with the residue 641 substituted with Phosphoserine" [UniProtKB:P35221] xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0011368 name: CTNA1_HUMAN-Phosphoserine652 def: "Protein CTNA1_HUMAN with the residue 652 substituted with Phosphoserine" [UniProtKB:P35221] xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0011369 name: CTNA1_HUMAN-Phosphothreonine654 def: "Protein CTNA1_HUMAN with the residue 654 substituted with Phosphothreonine" [UniProtKB:P35221] comment: By similarity xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0011370 name: CTNA1_HUMAN-Phosphoserine655 def: "Protein CTNA1_HUMAN with the residue 655 substituted with Phosphoserine" [UniProtKB:P35221] xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003605 ! vinculin binding relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000464 ! adherens junction relationship: located_in CCO:C0000467 ! zonula adherens relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0011371 name: CTNA1_HUMAN-Phosphothreonine658 def: "Protein CTNA1_HUMAN with the residue 658 substituted with Phosphothreonine" [UniProtKB:P35221] xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0011372 name: CTNB1_HUMAN-Phosphoserine23 def: "Protein CTNB1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:P35222] comment: by GSK3-beta; xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011373 name: CTNB1_HUMAN-Phosphoserine29 def: "Protein CTNB1_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:P35222] comment: by GSK3-beta; xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011374 name: CTNB1_HUMAN-Phosphoserine33 def: "Protein CTNB1_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:P35222] comment: by GSK3-beta; xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011375 name: CTNB1_HUMAN-Phosphoserine37 def: "Protein CTNB1_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:P35222] comment: by GSK3-beta; xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011376 name: CTNB1_HUMAN-Phosphothreonine41 def: "Protein CTNB1_HUMAN with the residue 41 substituted with Phosphothreonine" [UniProtKB:P35222] comment: by GSK3-beta; xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011377 name: CTNB1_HUMAN-Phosphoserine45 def: "Protein CTNB1_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:P35222] xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011378 name: CTNB1_HUMAN-Phosphotyrosine86 def: "Protein CTNB1_HUMAN with the residue 86 substituted with Phosphotyrosine" [UniProtKB:P35222] comment: by CSK; xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0006102 ! alpha-catenin binding relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000468 ! fascia adherens relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000783 ! lateral plasma membrane relationship: located_in CCO:C0000934 ! Z disc relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001067 ! beta-catenin destruction complex relationship: located_in CCO:C0001292 ! microvillus membrane relationship: located_in CCO:C0001769 ! apical junction complex relationship: located_in CCO:C0001896 ! apical part of cell relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011379 name: CTNB1_HUMAN-Phosphoserine191 def: "Protein CTNB1_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:P35222] comment: By similarity xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011380 name: CTNB1_HUMAN-Phosphothreonine551 def: "Protein CTNB1_HUMAN with the residue 551 substituted with Phosphothreonine" [UniProtKB:P35222] xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011381 name: CTNB1_HUMAN-Phosphoserine552 def: "Protein CTNB1_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:P35222] xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011382 name: CTNB1_HUMAN-Phosphothreonine556 def: "Protein CTNB1_HUMAN with the residue 556 substituted with Phosphothreonine" [UniProtKB:P35222] xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011383 name: CTNB1_HUMAN-Phosphotyrosine654 def: "Protein CTNB1_HUMAN with the residue 654 substituted with Phosphotyrosine" [UniProtKB:P35222] comment: by CSK; xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011384 name: CTNB1_HUMAN-Phosphoserine675 def: "Protein CTNB1_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:P35222] xref: UniProtKB:P35222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:B0011385 name: CTND1_HUMAN-Phosphoserine47 def: "Protein CTND1_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011386 name: CTND1_HUMAN-Phosphotyrosine96 def: "Protein CTND1_HUMAN with the residue 96 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011387 name: CTND1_HUMAN-Phosphotyrosine174 def: "Protein CTND1_HUMAN with the residue 174 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011388 name: CTND1_HUMAN-Phosphotyrosine217 def: "Protein CTND1_HUMAN with the residue 217 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011389 name: CTND1_HUMAN-Phosphotyrosine228 def: "Protein CTND1_HUMAN with the residue 228 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011390 name: CTND1_HUMAN-Phosphotyrosine257 def: "Protein CTND1_HUMAN with the residue 257 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011391 name: CTND1_HUMAN-Phosphoserine268 def: "Protein CTND1_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011392 name: CTND1_HUMAN-Phosphoserine269 def: "Protein CTND1_HUMAN with the residue 269 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011393 name: CTND1_HUMAN-Phosphotyrosine280 def: "Protein CTND1_HUMAN with the residue 280 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011394 name: CTND1_HUMAN-Phosphoserine288 def: "Protein CTND1_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011395 name: CTND1_HUMAN-Phosphotyrosine291 def: "Protein CTND1_HUMAN with the residue 291 substituted with Phosphotyrosine" [UniProtKB:O60716] comment: By similarity xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011396 name: CTND1_HUMAN-Phosphotyrosine302 def: "Protein CTND1_HUMAN with the residue 302 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011397 name: CTND1_HUMAN-Phosphothreonine310 def: "Protein CTND1_HUMAN with the residue 310 substituted with Phosphothreonine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011398 name: CTND1_HUMAN-Phosphoserine320 def: "Protein CTND1_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:O60716] comment: By similarity xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011399 name: CTND1_HUMAN-Phosphotyrosine321 def: "Protein CTND1_HUMAN with the residue 321 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011400 name: CTND1_HUMAN-Phosphotyrosine334 def: "Protein CTND1_HUMAN with the residue 334 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011401 name: CTND1_HUMAN-Phosphoserine349 def: "Protein CTND1_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011402 name: CTND1_HUMAN-Phosphoserine352 def: "Protein CTND1_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011403 name: CTND1_HUMAN-Phosphoserine859 def: "Protein CTND1_HUMAN with the residue 859 substituted with Phosphoserine" [UniProtKB:O60716] comment: By similarity xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011404 name: CTND1_HUMAN-Phosphotyrosine865 def: "Protein CTND1_HUMAN with the residue 865 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011405 name: CTND1_HUMAN-Phosphothreonine916 def: "Protein CTND1_HUMAN with the residue 916 substituted with Phosphothreonine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0011406 name: CTRO_HUMAN-Phosphoserine440 def: "Protein CTRO_HUMAN with the residue 440 substituted with Phosphoserine" [UniProtKB:O14578] xref: UniProtKB:O14578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001356 ! CTRO_HUMAN [Term] id: CCO:B0011407 name: CTRO_HUMAN-Phosphoserine480 def: "Protein CTRO_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:O14578] comment: By similarity xref: UniProtKB:O14578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001356 ! CTRO_HUMAN [Term] id: CCO:B0011408 name: CTRO_HUMAN-Phosphoserine1582 def: "Protein CTRO_HUMAN with the residue 1582 substituted with Phosphoserine" [UniProtKB:O14578] comment: By similarity xref: UniProtKB:O14578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001356 ! CTRO_HUMAN [Term] id: CCO:B0011409 name: CTRO_HUMAN-Phosphoserine1971 def: "Protein CTRO_HUMAN with the residue 1971 substituted with Phosphoserine" [UniProtKB:O14578] xref: UniProtKB:O14578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001356 ! CTRO_HUMAN [Term] id: CCO:B0011410 name: CTRO_HUMAN-Phosphoserine1993 def: "Protein CTRO_HUMAN with the residue 1993 substituted with Phosphoserine" [UniProtKB:O14578] xref: UniProtKB:O14578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001356 ! CTRO_HUMAN [Term] id: CCO:B0011411 name: CUL2_HUMAN-Phosphotyrosine394 def: "Protein CUL2_HUMAN with the residue 394 substituted with Phosphotyrosine" [UniProtKB:Q13617] comment: By similarity xref: UniProtKB:Q13617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001760 ! CUL2_HUMAN [Term] id: CCO:B0011412 name: CUL3_HUMAN-Phosphotyrosine58 def: "Protein CUL3_HUMAN with the residue 58 substituted with Phosphotyrosine" [UniProtKB:Q13618] xref: UniProtKB:Q13618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001761 ! CUL3_HUMAN [Term] id: CCO:B0011413 name: CUL3_HUMAN-Phosphoserine737 def: "Protein CUL3_HUMAN with the residue 737 substituted with Phosphoserine" [UniProtKB:Q13618] xref: UniProtKB:Q13618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: transformation_of CCO:B0001761 ! CUL3_HUMAN [Term] id: CCO:B0011419 name: CYLD_HUMAN-Phosphoserine399 def: "Protein CYLD_HUMAN with the residue 399 substituted with Phosphoserine" [UniProtKB:Q9NQC7] xref: UniProtKB:Q9NQC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002153 ! CYLD_HUMAN [Term] id: CCO:B0011420 name: CYTSA_HUMAN-Phosphoserine54 def: "Protein CYTSA_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q69YQ0] comment: By similarity xref: UniProtKB:Q69YQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001906 ! CYTSA_HUMAN [Term] id: CCO:B0011421 name: CYTSA_HUMAN-Phosphoserine220 def: "Protein CYTSA_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q69YQ0] xref: UniProtKB:Q69YQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001906 ! CYTSA_HUMAN [Term] id: CCO:B0011422 name: DAB2P_HUMAN-Phosphoserine702 def: "Protein DAB2P_HUMAN with the residue 702 substituted with Phosphoserine" [UniProtKB:Q5VWQ8] xref: UniProtKB:Q5VWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001899 ! DAB2P_HUMAN [Term] id: CCO:B0011423 name: DACH1_HUMAN-Phosphothreonine578 def: "Protein DACH1_HUMAN with the residue 578 substituted with Phosphothreonine" [UniProtKB:Q9UI36] xref: UniProtKB:Q9UI36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005195 ! DACH1_HUMAN [Term] id: CCO:B0011424 name: DACH1_HUMAN-Phosphoserine581 def: "Protein DACH1_HUMAN with the residue 581 substituted with Phosphoserine" [UniProtKB:Q9UI36] xref: UniProtKB:Q9UI36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005195 ! DACH1_HUMAN [Term] id: CCO:B0011425 name: DACH1_HUMAN-Phosphothreonine582 def: "Protein DACH1_HUMAN with the residue 582 substituted with Phosphothreonine" [UniProtKB:Q9UI36] xref: UniProtKB:Q9UI36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005195 ! DACH1_HUMAN [Term] id: CCO:B0011426 name: DACH1_HUMAN-Phosphothreonine584 def: "Protein DACH1_HUMAN with the residue 584 substituted with Phosphothreonine" [UniProtKB:Q9UI36] xref: UniProtKB:Q9UI36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005195 ! DACH1_HUMAN [Term] id: CCO:B0011427 name: DAPK1_HUMAN-Phosphoserine308 def: "Protein DAPK1_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:P53355] comment: by autocatalysis; xref: UniProtKB:P53355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005482 ! DAPK1_HUMAN [Term] id: CCO:B0011428 name: DAXX_HUMAN-Phosphoserine213 def: "Protein DAXX_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011429 name: DAXX_HUMAN-Phosphothreonine459 def: "Protein DAXX_HUMAN with the residue 459 substituted with Phosphothreonine" [UniProtKB:Q9UER7] comment: By similarity xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011430 name: DAXX_HUMAN-Phosphoserine495 def: "Protein DAXX_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011431 name: DAXX_HUMAN-Phosphotyrosine648 def: "Protein DAXX_HUMAN with the residue 648 substituted with Phosphotyrosine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011432 name: DAXX_HUMAN-Phosphoserine668 def: "Protein DAXX_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011433 name: DAXX_HUMAN-Phosphoserine671 def: "Protein DAXX_HUMAN with the residue 671 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011434 name: DAXX_HUMAN-Phosphothreonine709 def: "Protein DAXX_HUMAN with the residue 709 substituted with Phosphothreonine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011435 name: DAXX_HUMAN-Phosphoserine712 def: "Protein DAXX_HUMAN with the residue 712 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011436 name: DAXX_HUMAN-Phosphoserine737 def: "Protein DAXX_HUMAN with the residue 737 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011437 name: DAXX_HUMAN-Phosphoserine739 def: "Protein DAXX_HUMAN with the residue 739 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0011441 name: DC1I1_HUMAN-Phosphoserine635 def: "Protein DC1I1_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:O14576] comment: By similarity xref: UniProtKB:O14576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000428 ! cytoplasmic dynein complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000995 ! dynein complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0005648 ! DC1I1_HUMAN [Term] id: CCO:B0011442 name: DCP1A_HUMAN-Phosphoserine353 def: "Protein DCP1A_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0011443 name: DCP1A_HUMAN-Phosphoserine523 def: "Protein DCP1A_HUMAN with the residue 523 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0011444 name: DCP1A_HUMAN-Phosphoserine525 def: "Protein DCP1A_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0011445 name: DCP2_HUMAN-Phosphoserine246 def: "Protein DCP2_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q8IU60] xref: UniProtKB:Q8IU60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:B0011446 name: DCP2_HUMAN-Phosphoserine247 def: "Protein DCP2_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:Q8IU60] xref: UniProtKB:Q8IU60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:B0011447 name: DCP2_HUMAN-Phosphoserine249 def: "Protein DCP2_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q8IU60] xref: UniProtKB:Q8IU60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:B0011448 name: DCP2_HUMAN-Phosphoserine276 def: "Protein DCP2_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q8IU60] xref: UniProtKB:Q8IU60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:B0011449 name: DCP2_HUMAN-Phosphoserine284 def: "Protein DCP2_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q8IU60] xref: UniProtKB:Q8IU60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:B0011450 name: DCP2_HUMAN-Phosphoserine347 def: "Protein DCP2_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q8IU60] xref: UniProtKB:Q8IU60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:B0011451 name: DCR1A_HUMAN-Phosphoserine590 def: "Protein DCR1A_HUMAN with the residue 590 substituted with Phosphoserine" [UniProtKB:Q6PJP8] comment: By similarity xref: UniProtKB:Q6PJP8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001916 ! DCR1A_HUMAN [Term] id: CCO:B0011452 name: DCTN1_HUMAN-Phosphoserine541 def: "Protein DCTN1_HUMAN with the residue 541 substituted with Phosphoserine" [UniProtKB:Q14203] comment: By similarity xref: UniProtKB:Q14203 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000995 ! dynein complex relationship: transformation_of CCO:B0001779 ! DCTN1_HUMAN [Term] id: CCO:B0011453 name: DCTN2_HUMAN-Phosphoserine83 def: "Protein DCTN2_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q13561] comment: By similarity xref: UniProtKB:Q13561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005177 ! DCTN2_HUMAN [Term] id: CCO:B0011454 name: DDB1_HUMAN-Phosphothreonine8 def: "Protein DDB1_HUMAN with the residue 8 substituted with Phosphothreonine" [UniProtKB:Q16531] comment: By similarity xref: UniProtKB:Q16531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:B0011455 name: DDB1_HUMAN-Phosphoserine757 def: "Protein DDB1_HUMAN with the residue 757 substituted with Phosphoserine" [UniProtKB:Q16531] comment: By similarity xref: UniProtKB:Q16531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:B0011456 name: DDB1_HUMAN-Phosphoserine766 def: "Protein DDB1_HUMAN with the residue 766 substituted with Phosphoserine" [UniProtKB:Q16531] comment: By similarity xref: UniProtKB:Q16531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:B0011457 name: DDB2_HUMAN-Phosphoserine24 def: "Protein DDB2_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q92466] xref: UniProtKB:Q92466 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0005658 ! DDB2_HUMAN [Term] id: CCO:B0011458 name: DDB2_HUMAN-Phosphoserine26 def: "Protein DDB2_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q92466] xref: UniProtKB:Q92466 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005658 ! DDB2_HUMAN [Term] id: CCO:B0011459 name: DDR1_HUMAN-Phosphotyrosine513 def: "Protein DDR1_HUMAN with the residue 513 substituted with Phosphotyrosine" [UniProtKB:Q08345] comment: by autocatalysis; By similarity xref: UniProtKB:Q08345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006158 ! DDR1_HUMAN [Term] id: CCO:B0011460 name: DDR1_HUMAN-Phosphotyrosine792 def: "Protein DDR1_HUMAN with the residue 792 substituted with Phosphotyrosine" [UniProtKB:Q08345] comment: by autocatalysis; By similarity xref: UniProtKB:Q08345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0006158 ! DDR1_HUMAN [Term] id: CCO:B0011461 name: DDR1_HUMAN-Phosphotyrosine796 def: "Protein DDR1_HUMAN with the residue 796 substituted with Phosphotyrosine" [UniProtKB:Q08345] comment: by autocatalysis; By similarity xref: UniProtKB:Q08345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006158 ! DDR1_HUMAN [Term] id: CCO:B0011462 name: DDR1_HUMAN-Phosphotyrosine797 def: "Protein DDR1_HUMAN with the residue 797 substituted with Phosphotyrosine" [UniProtKB:Q08345] comment: by autocatalysis; By similarity xref: UniProtKB:Q08345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006158 ! DDR1_HUMAN [Term] id: CCO:B0011463 name: DDX21_HUMAN-Phosphoserine71 def: "Protein DDX21_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0011464 name: DDX21_HUMAN-Phosphoserine89 def: "Protein DDX21_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0011465 name: DDX21_HUMAN-Phosphoserine121 def: "Protein DDX21_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0011466 name: DDX21_HUMAN-Phosphoserine171 def: "Protein DDX21_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0011467 name: DDX24_HUMAN-Phosphoserine82 def: "Protein DDX24_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q9GZR7] xref: UniProtKB:Q9GZR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:B0011468 name: DDX24_HUMAN-Phosphoserine166 def: "Protein DDX24_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q9GZR7] xref: UniProtKB:Q9GZR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:B0011469 name: DDX24_HUMAN-Phosphoserine192 def: "Protein DDX24_HUMAN with the residue 192 substituted with Phosphoserine" [UniProtKB:Q9GZR7] xref: UniProtKB:Q9GZR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:B0011470 name: DDX24_HUMAN-Phosphothreonine302 def: "Protein DDX24_HUMAN with the residue 302 substituted with Phosphothreonine" [UniProtKB:Q9GZR7] xref: UniProtKB:Q9GZR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:B0011471 name: DDX3X_HUMAN-N-acetylserine2 def: "Protein DDX3X_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011472 name: DDX3X_HUMAN-Phosphotyrosine69 def: "Protein DDX3X_HUMAN with the residue 69 substituted with Phosphotyrosine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011473 name: DDX3X_HUMAN-Phosphoserine74 def: "Protein DDX3X_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011474 name: DDX3X_HUMAN-Phosphoserine76 def: "Protein DDX3X_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011475 name: DDX3X_HUMAN-Phosphoserine78 def: "Protein DDX3X_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011476 name: DDX3X_HUMAN-Phosphotyrosine104 def: "Protein DDX3X_HUMAN with the residue 104 substituted with Phosphotyrosine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011477 name: DDX3X_HUMAN-Phosphoserine125 def: "Protein DDX3X_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011478 name: DDX3X_HUMAN-Phosphotyrosine343 def: "Protein DDX3X_HUMAN with the residue 343 substituted with Phosphotyrosine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011479 name: DDX3X_HUMAN-Phosphoserine590 def: "Protein DDX3X_HUMAN with the residue 590 substituted with Phosphoserine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011480 name: DDX3X_HUMAN-Phosphoserine594 def: "Protein DDX3X_HUMAN with the residue 594 substituted with Phosphoserine" [UniProtKB:O00571] xref: UniProtKB:O00571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:B0011481 name: DDX5_HUMAN-Phosphoserine30 def: "Protein DDX5_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:P17844] xref: UniProtKB:P17844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005729 ! DDX5_HUMAN [Term] id: CCO:B0011482 name: DDX5_HUMAN-Phosphotyrosine297 def: "Protein DDX5_HUMAN with the residue 297 substituted with Phosphotyrosine" [UniProtKB:P17844] xref: UniProtKB:P17844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005729 ! DDX5_HUMAN [Term] id: CCO:B0011483 name: DDX5_HUMAN-Omega-N-methylated arginine502 def: "Protein DDX5_HUMAN with the residue 502 substituted with Omega-N-methylated arginine" [UniProtKB:P17844] xref: UniProtKB:P17844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005729 ! DDX5_HUMAN [Term] id: CCO:B0011484 name: DDX5_HUMAN-Phosphothreonine507 def: "Protein DDX5_HUMAN with the residue 507 substituted with Phosphothreonine" [UniProtKB:P17844] xref: UniProtKB:P17844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005729 ! DDX5_HUMAN [Term] id: CCO:B0011485 name: DDX5_HUMAN-Phosphoserine520 def: "Protein DDX5_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:P17844] xref: UniProtKB:P17844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005729 ! DDX5_HUMAN [Term] id: CCO:B0011486 name: DDX6_HUMAN-Phosphothreonine36 def: "Protein DDX6_HUMAN with the residue 36 substituted with Phosphothreonine" [UniProtKB:P26196] xref: UniProtKB:P26196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0002047 ! stress granule relationship: transformation_of CCO:B0006013 ! DDX6_HUMAN [Term] id: CCO:B0011487 name: DEK_HUMAN-Phosphoserine32 def: "Protein DEK_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011488 name: DEK_HUMAN-Phosphoserine51 def: "Protein DEK_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011489 name: DEK_HUMAN-Phosphoserine227 def: "Protein DEK_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011490 name: DEK_HUMAN-Phosphoserine230 def: "Protein DEK_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011491 name: DEK_HUMAN-Phosphoserine231 def: "Protein DEK_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011492 name: DEK_HUMAN-Phosphoserine232 def: "Protein DEK_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011493 name: DEK_HUMAN-Phosphoserine243 def: "Protein DEK_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011494 name: DEK_HUMAN-Phosphoserine244 def: "Protein DEK_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011495 name: DEK_HUMAN-Phosphoserine251 def: "Protein DEK_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011496 name: DEK_HUMAN-Phosphoserine276 def: "Protein DEK_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011497 name: DEK_HUMAN-Phosphoserine301 def: "Protein DEK_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011498 name: DEK_HUMAN-Phosphoserine303 def: "Protein DEK_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011499 name: DEK_HUMAN-Phosphoserine306 def: "Protein DEK_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011500 name: DEK_HUMAN-Phosphoserine307 def: "Protein DEK_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:P35659] xref: UniProtKB:P35659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005342 ! DEK_HUMAN [Term] id: CCO:B0011501 name: DHC24_HUMAN-Phosphothreonine110 def: "Protein DHC24_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:Q15392] xref: UniProtKB:Q15392 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001806 ! DHC24_HUMAN [Term] id: CCO:B0011506 name: DHX9_HUMAN-Phosphoserine87 def: "Protein DHX9_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q08211] xref: UniProtKB:Q08211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:B0011507 name: DHX9_HUMAN-Phosphoserine321 def: "Protein DHX9_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q08211] xref: UniProtKB:Q08211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:B0011508 name: DHX9_HUMAN-Phosphotyrosine1234 def: "Protein DHX9_HUMAN with the residue 1234 substituted with Phosphotyrosine" [UniProtKB:Q08211] xref: UniProtKB:Q08211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:B0011509 name: DHX9_HUMAN-Phosphotyrosine1241 def: "Protein DHX9_HUMAN with the residue 1241 substituted with Phosphotyrosine" [UniProtKB:Q08211] xref: UniProtKB:Q08211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:B0011511 name: DKC1_HUMAN-N-acetylalanine2 def: "Protein DKC1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011512 name: DKC1_HUMAN-Phosphoserine21 def: "Protein DKC1_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011513 name: DKC1_HUMAN-Phosphoserine451 def: "Protein DKC1_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011514 name: DKC1_HUMAN-Phosphoserine453 def: "Protein DKC1_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011515 name: DKC1_HUMAN-Phosphoserine455 def: "Protein DKC1_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011516 name: DKC1_HUMAN-Phosphothreonine458 def: "Protein DKC1_HUMAN with the residue 458 substituted with Phosphothreonine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011517 name: DKC1_HUMAN-Phosphoserine485 def: "Protein DKC1_HUMAN with the residue 485 substituted with Phosphoserine" [UniProtKB:O60832] comment: By similarity xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011518 name: DKC1_HUMAN-Phosphoserine494 def: "Protein DKC1_HUMAN with the residue 494 substituted with Phosphoserine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011519 name: DKC1_HUMAN-Phosphoserine513 def: "Protein DKC1_HUMAN with the residue 513 substituted with Phosphoserine" [UniProtKB:O60832] xref: UniProtKB:O60832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000306 ! telomerase activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000297 ! telomerase holoenzyme complex relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0001415 ! DKC1_HUMAN [Term] id: CCO:B0011520 name: DLG1_HUMAN-Phosphoserine232 def: "Protein DLG1_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q12959] comment: By similarity xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0011521 name: DLG1_HUMAN-Phosphoserine301 def: "Protein DLG1_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:Q12959] comment: By similarity xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000802 ! guanylate kinase activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0002867 ! potassium channel regulator activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004211 ! phosphatase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0011522 name: DLG1_HUMAN-Phosphothreonine683 def: "Protein DLG1_HUMAN with the residue 683 substituted with Phosphothreonine" [UniProtKB:Q12959] comment: By similarity xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0011523 name: DLG1_HUMAN-Phosphoserine684 def: "Protein DLG1_HUMAN with the residue 684 substituted with Phosphoserine" [UniProtKB:Q12959] xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0011524 name: DLG1_HUMAN-Phosphoserine687 def: "Protein DLG1_HUMAN with the residue 687 substituted with Phosphoserine" [UniProtKB:Q12959] xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0011525 name: DLG5_HUMAN-Phosphothreonine984 def: "Protein DLG5_HUMAN with the residue 984 substituted with Phosphothreonine" [UniProtKB:Q8TDM6] xref: UniProtKB:Q8TDM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001993 ! DLG5_HUMAN [Term] id: CCO:B0011526 name: DLG5_HUMAN-Phosphoserine1000 def: "Protein DLG5_HUMAN with the residue 1000 substituted with Phosphoserine" [UniProtKB:Q8TDM6] xref: UniProtKB:Q8TDM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001993 ! DLG5_HUMAN [Term] id: CCO:B0011527 name: DLG5_HUMAN-Phosphothreonine1011 def: "Protein DLG5_HUMAN with the residue 1011 substituted with Phosphothreonine" [UniProtKB:Q8TDM6] xref: UniProtKB:Q8TDM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0001993 ! DLG5_HUMAN [Term] id: CCO:B0011543 name: DLRB1_HUMAN-N-acetylalanine2 def: "Protein DLRB1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9NP97] comment: By similarity xref: UniProtKB:Q9NP97 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005562 ! DLRB1_HUMAN [Term] id: CCO:B0011544 name: DMAP1_HUMAN-Phosphothreonine445 def: "Protein DMAP1_HUMAN with the residue 445 substituted with Phosphothreonine" [UniProtKB:Q9NPF5] xref: UniProtKB:Q9NPF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005365 ! DMAP1_HUMAN [Term] id: CCO:B0011545 name: DMAP1_HUMAN-Phosphoserine456 def: "Protein DMAP1_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:Q9NPF5] xref: UniProtKB:Q9NPF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005365 ! DMAP1_HUMAN [Term] id: CCO:B0011547 name: DNJA1_HUMAN-Phosphoserine83 def: "Protein DNJA1_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P31689] xref: UniProtKB:P31689 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:B0011548 name: DNJA1_HUMAN-Phosphoserine335 def: "Protein DNJA1_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:P31689] xref: UniProtKB:P31689 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:B0011549 name: DNJA1_HUMAN-Phosphotyrosine381 def: "Protein DNJA1_HUMAN with the residue 381 substituted with Phosphotyrosine" [UniProtKB:P31689] xref: UniProtKB:P31689 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:B0011550 name: DNJA2_HUMAN-Phosphoserine78 def: "Protein DNJA2_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:O60884] xref: UniProtKB:O60884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001418 ! DNJA2_HUMAN [Term] id: CCO:B0011551 name: DNJA3_HUMAN-Phosphoserine169 def: "Protein DNJA3_HUMAN with the residue 169 substituted with Phosphoserine" [UniProtKB:Q96EY1] xref: UniProtKB:Q96EY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:B0011552 name: DNJB6_HUMAN-Phosphoserine277 def: "Protein DNJB6_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:O75190] xref: UniProtKB:O75190 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000200 ! ATPase activator activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0005696 ! DNJB6_HUMAN [Term] id: CCO:B0011565 name: DOCK1_HUMAN-Phosphoserine1858 def: "Protein DOCK1_HUMAN with the residue 1858 substituted with Phosphoserine" [UniProtKB:Q14185] xref: UniProtKB:Q14185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:B0011566 name: DP13A_HUMAN-Phosphoserine401 def: "Protein DP13A_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:Q9UKG1] xref: UniProtKB:Q9UKG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002219 ! DP13A_HUMAN [Term] id: CCO:B0011567 name: DP13A_HUMAN-Phosphoserine691 def: "Protein DP13A_HUMAN with the residue 691 substituted with Phosphoserine" [UniProtKB:Q9UKG1] xref: UniProtKB:Q9UKG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000805 ! NuRD complex relationship: located_in CCO:C0001339 ! early endosome membrane relationship: transformation_of CCO:B0002219 ! DP13A_HUMAN [Term] id: CCO:B0011568 name: DPOA2_HUMAN-Phosphothreonine127 def: "Protein DPOA2_HUMAN with the residue 127 substituted with Phosphothreonine" [UniProtKB:Q14181] xref: UniProtKB:Q14181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:B0011569 name: DPOA2_HUMAN-Phosphothreonine130 def: "Protein DPOA2_HUMAN with the residue 130 substituted with Phosphothreonine" [UniProtKB:Q14181] xref: UniProtKB:Q14181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:B0011570 name: DPOA2_HUMAN-Phosphoserine141 def: "Protein DPOA2_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q14181] xref: UniProtKB:Q14181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:B0011571 name: DPOA2_HUMAN-Phosphoserine152 def: "Protein DPOA2_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q14181] xref: UniProtKB:Q14181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:B0011572 name: DPOD3_HUMAN-Phosphoserine307 def: "Protein DPOD3_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q15054] xref: UniProtKB:Q15054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:B0011573 name: DPOD3_HUMAN-Phosphoserine407 def: "Protein DPOD3_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q15054] xref: UniProtKB:Q15054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:B0011574 name: DPOD3_HUMAN-Phosphoserine409 def: "Protein DPOD3_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q15054] xref: UniProtKB:Q15054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:B0011575 name: DPOD3_HUMAN-Phosphothreonine411 def: "Protein DPOD3_HUMAN with the residue 411 substituted with Phosphothreonine" [UniProtKB:Q15054] xref: UniProtKB:Q15054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:B0011576 name: DPOD3_HUMAN-Phosphoserine413 def: "Protein DPOD3_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q15054] xref: UniProtKB:Q15054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:B0011577 name: DPOE1_HUMAN-Phosphoserine1940 def: "Protein DPOE1_HUMAN with the residue 1940 substituted with Phosphoserine" [UniProtKB:Q07864] xref: UniProtKB:Q07864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001724 ! DPOE1_HUMAN [Term] id: CCO:B0011578 name: DPOE3_HUMAN-Phosphoserine122 def: "Protein DPOE3_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q9NRF9] xref: UniProtKB:Q9NRF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005885 ! DPOE3_HUMAN [Term] id: CCO:B0011579 name: DPOE4_HUMAN-Phosphoserine25 def: "Protein DPOE4_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q9NR33] xref: UniProtKB:Q9NR33 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:B0011580 name: DPOLA_HUMAN-Phosphoserine186 def: "Protein DPOLA_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:P09884] comment: By similarity xref: UniProtKB:P09884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000407 ! DNA primase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000266 ! alpha DNA polymerase:primase complex relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0001503 ! DPOLA_HUMAN [Term] id: CCO:B0011581 name: DPYL1_HUMAN-Phosphothreonine509 def: "Protein DPYL1_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q14194] comment: By similarity xref: UniProtKB:Q14194 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:B0011582 name: DREB_HUMAN-N-acetylalanine2 def: "Protein DREB_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011583 name: DREB_HUMAN-Phosphoserine134 def: "Protein DREB_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q16643] comment: By similarity xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011584 name: DREB_HUMAN-Phosphoserine141 def: "Protein DREB_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011585 name: DREB_HUMAN-Phosphoserine142 def: "Protein DREB_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011586 name: DREB_HUMAN-Phosphoserine337 def: "Protein DREB_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011587 name: DREB_HUMAN-Phosphoserine339 def: "Protein DREB_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011588 name: DREB_HUMAN-Phosphoserine342 def: "Protein DREB_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:Q16643] comment: By similarity xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011589 name: DREB_HUMAN-Phosphothreonine346 def: "Protein DREB_HUMAN with the residue 346 substituted with Phosphothreonine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011590 name: DREB_HUMAN-Phosphotyrosine622 def: "Protein DREB_HUMAN with the residue 622 substituted with Phosphotyrosine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0011591 name: DSN1_HUMAN-Phosphoserine28 def: "Protein DSN1_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q9H410] xref: UniProtKB:Q9H410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002134 ! DSN1_HUMAN [Term] id: CCO:B0011592 name: DSN1_HUMAN-Phosphoserine30 def: "Protein DSN1_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q9H410] xref: UniProtKB:Q9H410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002134 ! DSN1_HUMAN [Term] id: CCO:B0011593 name: DSN1_HUMAN-Phosphoserine86 def: "Protein DSN1_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q9H410] xref: UniProtKB:Q9H410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002134 ! DSN1_HUMAN [Term] id: CCO:B0011594 name: DTL_HUMAN-Phosphoserine426 def: "Protein DTL_HUMAN with the residue 426 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0011595 name: DTL_HUMAN-Phosphothreonine516 def: "Protein DTL_HUMAN with the residue 516 substituted with Phosphothreonine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0011596 name: DTL_HUMAN-Phosphoserine599 def: "Protein DTL_HUMAN with the residue 599 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] comment: By similarity xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0011597 name: DTL_HUMAN-Phosphoserine717 def: "Protein DTL_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0011602 name: DYN2_HUMAN-Phosphoserine298 def: "Protein DYN2_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:P50570] comment: By similarity xref: UniProtKB:P50570 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001643 ! DYN2_HUMAN [Term] id: CCO:B0011603 name: DYN2_HUMAN-Phosphoserine302 def: "Protein DYN2_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:P50570] comment: By similarity xref: UniProtKB:P50570 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001643 ! DYN2_HUMAN [Term] id: CCO:B0011604 name: DYN2_HUMAN-Phosphotyrosine597 def: "Protein DYN2_HUMAN with the residue 597 substituted with Phosphotyrosine" [UniProtKB:P50570] comment: By similarity xref: UniProtKB:P50570 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0001643 ! DYN2_HUMAN [Term] id: CCO:B0011605 name: DYN2_HUMAN-Phosphothreonine766 def: "Protein DYN2_HUMAN with the residue 766 substituted with Phosphothreonine" [UniProtKB:P50570] xref: UniProtKB:P50570 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001643 ! DYN2_HUMAN [Term] id: CCO:B0011606 name: E2AK1_HUMAN-Phosphoserine275 def: "Protein E2AK1_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q9BQI3] xref: UniProtKB:Q9BQI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:B0011607 name: E2AK1_HUMAN-Phosphoserine276 def: "Protein E2AK1_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q9BQI3] xref: UniProtKB:Q9BQI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:B0011608 name: E2AK1_HUMAN-Phosphoserine277 def: "Protein E2AK1_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q9BQI3] xref: UniProtKB:Q9BQI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:B0011609 name: E2AK1_HUMAN-Phosphoserine278 def: "Protein E2AK1_HUMAN with the residue 278 substituted with Phosphoserine" [UniProtKB:Q9BQI3] xref: UniProtKB:Q9BQI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:B0011610 name: E2AK1_HUMAN-Phosphothreonine488 def: "Protein E2AK1_HUMAN with the residue 488 substituted with Phosphothreonine" [UniProtKB:Q9BQI3] comment: by autocatalysis; By similarity xref: UniProtKB:Q9BQI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001061 ! eukaryotic translation initiation factor 2alpha kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:B0011611 name: E2AK2_HUMAN-Phosphoserine83 def: "Protein E2AK2_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P19525] comment: by autocatalysis; Probable xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011612 name: E2AK2_HUMAN-Phosphothreonine88 def: "Protein E2AK2_HUMAN with the residue 88 substituted with Phosphothreonine" [UniProtKB:P19525] comment: by autocatalysis; Probable xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001061 ! eukaryotic translation initiation factor 2alpha kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011613 name: E2AK2_HUMAN-Phosphothreonine89 def: "Protein E2AK2_HUMAN with the residue 89 substituted with Phosphothreonine" [UniProtKB:P19525] comment: by autocatalysis; Probable xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011614 name: E2AK2_HUMAN-Phosphothreonine90 def: "Protein E2AK2_HUMAN with the residue 90 substituted with Phosphothreonine" [UniProtKB:P19525] comment: by autocatalysis; Probable xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011615 name: E2AK2_HUMAN-Phosphoserine242 def: "Protein E2AK2_HUMAN with the residue 242 substituted with Phosphoserine" [UniProtKB:P19525] comment: by autocatalysis; Probable xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011616 name: E2AK2_HUMAN-Phosphothreonine255 def: "Protein E2AK2_HUMAN with the residue 255 substituted with Phosphothreonine" [UniProtKB:P19525] comment: by autocatalysis; Probable xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011617 name: E2AK2_HUMAN-Phosphothreonine258 def: "Protein E2AK2_HUMAN with the residue 258 substituted with Phosphothreonine" [UniProtKB:P19525] comment: by autocatalysis; Probable xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011618 name: E2AK2_HUMAN-Phosphothreonine446 def: "Protein E2AK2_HUMAN with the residue 446 substituted with Phosphothreonine" [UniProtKB:P19525] comment: by autocatalysis; xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011619 name: E2AK2_HUMAN-Phosphothreonine451 def: "Protein E2AK2_HUMAN with the residue 451 substituted with Phosphothreonine" [UniProtKB:P19525] comment: by autocatalysis; xref: UniProtKB:P19525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001535 ! E2AK2_HUMAN [Term] id: CCO:B0011620 name: E2F1_HUMAN-Phosphoserine375 def: "Protein E2F1_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:Q01094] xref: UniProtKB:Q01094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001713 ! E2F1_HUMAN [Term] id: CCO:B0011621 name: E2F6_HUMAN-Phosphoserine67 def: "Protein E2F6_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:O75461] comment: By similarity xref: UniProtKB:O75461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001429 ! E2F6_HUMAN [Term] id: CCO:B0011622 name: EAF1_HUMAN-Phosphoserine158 def: "Protein EAF1_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:Q96JC9] xref: UniProtKB:Q96JC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0005363 ! EAF1_HUMAN [Term] id: CCO:B0011623 name: EAF1_HUMAN-Phosphoserine165 def: "Protein EAF1_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q96JC9] xref: UniProtKB:Q96JC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005363 ! EAF1_HUMAN [Term] id: CCO:B0011624 name: EDC3_HUMAN-Phosphoserine131 def: "Protein EDC3_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:Q96F86] xref: UniProtKB:Q96F86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005717 ! EDC3_HUMAN [Term] id: CCO:B0011625 name: EDC4_HUMAN-Phosphothreonine693 def: "Protein EDC4_HUMAN with the residue 693 substituted with Phosphothreonine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011626 name: EDC4_HUMAN-Phosphoserine729 def: "Protein EDC4_HUMAN with the residue 729 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011627 name: EDC4_HUMAN-Phosphoserine741 def: "Protein EDC4_HUMAN with the residue 741 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011628 name: EDC4_HUMAN-Phosphoserine844 def: "Protein EDC4_HUMAN with the residue 844 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011629 name: EDC4_HUMAN-Phosphoserine875 def: "Protein EDC4_HUMAN with the residue 875 substituted with Phosphoserine" [UniProtKB:Q6P2E9] comment: By similarity xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011630 name: EDC4_HUMAN-Phosphoserine879 def: "Protein EDC4_HUMAN with the residue 879 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011631 name: EDC4_HUMAN-Phosphoserine887 def: "Protein EDC4_HUMAN with the residue 887 substituted with Phosphoserine" [UniProtKB:Q6P2E9] comment: By similarity xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011632 name: EDC4_HUMAN-Phosphoserine1067 def: "Protein EDC4_HUMAN with the residue 1067 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011633 name: EDC4_HUMAN-Phosphothreonine1072 def: "Protein EDC4_HUMAN with the residue 1072 substituted with Phosphothreonine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0011634 name: EF1A1_HUMAN-Phosphotyrosine29 def: "Protein EF1A1_HUMAN with the residue 29 substituted with Phosphotyrosine" [UniProtKB:P68104] xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011635 name: EF1A1_HUMAN-N6,N6,N6-trimethyllysine36 def: "Protein EF1A1_HUMAN with the residue 36 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68104] comment: By similarity xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000419 ! eukaryotic translation elongation factor 1 complex relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011636 name: EF1A1_HUMAN-N6,N6-dimethyllysine55 def: "Protein EF1A1_HUMAN with the residue 55 substituted with N6,N6-dimethyllysine" [UniProtKB:P68104] comment: By similarity xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011637 name: EF1A1_HUMAN-N6,N6,N6-trimethyllysine79 def: "Protein EF1A1_HUMAN with the residue 79 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68104] comment: By similarity xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011638 name: EF1A1_HUMAN-Phosphotyrosine162 def: "Protein EF1A1_HUMAN with the residue 162 substituted with Phosphotyrosine" [UniProtKB:P68104] xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011639 name: EF1A1_HUMAN-N6,N6-dimethyllysine165 def: "Protein EF1A1_HUMAN with the residue 165 substituted with N6,N6-dimethyllysine" [UniProtKB:P68104] comment: By similarity xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011640 name: EF1A1_HUMAN-N6,N6,N6-trimethyllysine318 def: "Protein EF1A1_HUMAN with the residue 318 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68104] comment: alternate; By similarity xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011641 name: EF1A1_HUMAN-N6-acetyllysine318 def: "Protein EF1A1_HUMAN with the residue 318 substituted with N6-acetyllysine" [UniProtKB:P68104] comment: alternate; xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0011642 name: EF1B_HUMAN-Phosphothreonine93 def: "Protein EF1B_HUMAN with the residue 93 substituted with Phosphothreonine" [UniProtKB:P24534] xref: UniProtKB:P24534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005752 ! EF1B_HUMAN [Term] id: CCO:B0011643 name: EF1B_HUMAN-Phosphoserine95 def: "Protein EF1B_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:P24534] xref: UniProtKB:P24534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005752 ! EF1B_HUMAN [Term] id: CCO:B0011644 name: EF1B_HUMAN-Phosphoserine106 def: "Protein EF1B_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:P24534] xref: UniProtKB:P24534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000419 ! eukaryotic translation elongation factor 1 complex relationship: transformation_of CCO:B0005752 ! EF1B_HUMAN [Term] id: CCO:B0011645 name: EF1B_HUMAN-Phosphotyrosine126 def: "Protein EF1B_HUMAN with the residue 126 substituted with Phosphotyrosine" [UniProtKB:P24534] xref: UniProtKB:P24534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005752 ! EF1B_HUMAN [Term] id: CCO:B0011646 name: EF1B_HUMAN-Phosphoserine128 def: "Protein EF1B_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:P24534] xref: UniProtKB:P24534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005752 ! EF1B_HUMAN [Term] id: CCO:B0011647 name: EF1B_HUMAN-Phosphoserine141 def: "Protein EF1B_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:P24534] xref: UniProtKB:P24534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005752 ! EF1B_HUMAN [Term] id: CCO:B0011648 name: EF1G_HUMAN-N-acetylalanine2 def: "Protein EF1G_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P26641] xref: UniProtKB:P26641 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000419 ! eukaryotic translation elongation factor 1 complex relationship: transformation_of CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:B0011649 name: EF1G_HUMAN-Phosphothreonine43 def: "Protein EF1G_HUMAN with the residue 43 substituted with Phosphothreonine" [UniProtKB:P26641] xref: UniProtKB:P26641 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:B0011650 name: EFNB1_HUMAN-Phosphoserine287 def: "Protein EFNB1_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:P98172] xref: UniProtKB:P98172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005815 ! EFNB1_HUMAN [Term] id: CCO:B0011651 name: EGFR_HUMAN-Phosphothreonine678 def: "Protein EGFR_HUMAN with the residue 678 substituted with Phosphothreonine" [UniProtKB:P00533] comment: by PKC; xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011652 name: EGFR_HUMAN-Phosphothreonine693 def: "Protein EGFR_HUMAN with the residue 693 substituted with Phosphothreonine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011653 name: EGFR_HUMAN-Phosphoserine695 def: "Protein EGFR_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011654 name: EGFR_HUMAN-Phosphotyrosine978 def: "Protein EGFR_HUMAN with the residue 978 substituted with Phosphotyrosine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011655 name: EGFR_HUMAN-Phosphoserine991 def: "Protein EGFR_HUMAN with the residue 991 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011656 name: EGFR_HUMAN-Phosphoserine995 def: "Protein EGFR_HUMAN with the residue 995 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001076 ! MAP/ERK kinase kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001343 ! epidermal growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004355 ! nitric-oxide synthase regulator activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000967 ! AP-2 adaptor complex relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011657 name: EGFR_HUMAN-Phosphotyrosine998 def: "Protein EGFR_HUMAN with the residue 998 substituted with Phosphotyrosine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011658 name: EGFR_HUMAN-Phosphoserine1026 def: "Protein EGFR_HUMAN with the residue 1026 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011659 name: EGFR_HUMAN-Phosphoserine1064 def: "Protein EGFR_HUMAN with the residue 1064 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011660 name: EGFR_HUMAN-Phosphotyrosine1069 def: "Protein EGFR_HUMAN with the residue 1069 substituted with Phosphotyrosine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011661 name: EGFR_HUMAN-Phosphoserine1070 def: "Protein EGFR_HUMAN with the residue 1070 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011662 name: EGFR_HUMAN-Phosphoserine1071 def: "Protein EGFR_HUMAN with the residue 1071 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011663 name: EGFR_HUMAN-Phosphotyrosine1092 def: "Protein EGFR_HUMAN with the residue 1092 substituted with Phosphotyrosine" [UniProtKB:P00533] comment: by autocatalysis; xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011664 name: EGFR_HUMAN-Phosphotyrosine1110 def: "Protein EGFR_HUMAN with the residue 1110 substituted with Phosphotyrosine" [UniProtKB:P00533] comment: by autocatalysis; xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011665 name: EGFR_HUMAN-Phosphotyrosine1138 def: "Protein EGFR_HUMAN with the residue 1138 substituted with Phosphotyrosine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011666 name: EGFR_HUMAN-Phosphoserine1166 def: "Protein EGFR_HUMAN with the residue 1166 substituted with Phosphoserine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011667 name: EGFR_HUMAN-Phosphotyrosine1172 def: "Protein EGFR_HUMAN with the residue 1172 substituted with Phosphotyrosine" [UniProtKB:P00533] comment: by autocatalysis; xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011668 name: EGFR_HUMAN-Phosphotyrosine1197 def: "Protein EGFR_HUMAN with the residue 1197 substituted with Phosphotyrosine" [UniProtKB:P00533] comment: by autocatalysis; xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0011669 name: EHMT1_HUMAN-Phosphoserine466 def: "Protein EHMT1_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q9H9B1] xref: UniProtKB:Q9H9B1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006006 ! EHMT1_HUMAN [Term] id: CCO:B0011670 name: ELF1_HUMAN-Phosphoserine168 def: "Protein ELF1_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:P32519] xref: UniProtKB:P32519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006027 ! ELF1_HUMAN [Term] id: CCO:B0011671 name: ELF1_HUMAN-Phosphoserine432 def: "Protein ELF1_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:P32519] xref: UniProtKB:P32519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006027 ! ELF1_HUMAN [Term] id: CCO:B0011672 name: ELF1_HUMAN-Phosphoserine474 def: "Protein ELF1_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:P32519] xref: UniProtKB:P32519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006027 ! ELF1_HUMAN [Term] id: CCO:B0011673 name: ELF1_HUMAN-Phosphothreonine566 def: "Protein ELF1_HUMAN with the residue 566 substituted with Phosphothreonine" [UniProtKB:P32519] xref: UniProtKB:P32519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006027 ! ELF1_HUMAN [Term] id: CCO:B0011674 name: ELK1_HUMAN-Phosphoserine324 def: "Protein ELK1_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:P19419] comment: by MAPK1; xref: UniProtKB:P19419 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005637 ! ELK1_HUMAN [Term] id: CCO:B0011675 name: ELK1_HUMAN-Phosphothreonine336 def: "Protein ELK1_HUMAN with the residue 336 substituted with Phosphothreonine" [UniProtKB:P19419] comment: by MAPK1; xref: UniProtKB:P19419 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005637 ! ELK1_HUMAN [Term] id: CCO:B0011676 name: ELK1_HUMAN-Phosphoserine383 def: "Protein ELK1_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:P19419] comment: by MAPK1; xref: UniProtKB:P19419 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005637 ! ELK1_HUMAN [Term] id: CCO:B0011677 name: ELK1_HUMAN-Phosphoserine389 def: "Protein ELK1_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:P19419] comment: by MAPK1; xref: UniProtKB:P19419 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005637 ! ELK1_HUMAN [Term] id: CCO:B0011678 name: ELK1_HUMAN-Phosphoserine422 def: "Protein ELK1_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:P19419] comment: by MAPK1; xref: UniProtKB:P19419 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005637 ! ELK1_HUMAN [Term] id: CCO:B0011679 name: ELOB_HUMAN-N-acetylmethionine1 def: "Protein ELOB_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q15370] comment: By similarity xref: UniProtKB:Q15370 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005668 ! ELOB_HUMAN [Term] id: CCO:B0011680 name: EMAL4_HUMAN-Phosphoserine87 def: "Protein EMAL4_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0011681 name: EMAL4_HUMAN-Phosphoserine144 def: "Protein EMAL4_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0011682 name: EMAL4_HUMAN-Phosphoserine146 def: "Protein EMAL4_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0011683 name: EMAL4_HUMAN-Phosphotyrosine226 def: "Protein EMAL4_HUMAN with the residue 226 substituted with Phosphotyrosine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0011684 name: EMAL4_HUMAN-Phosphotyrosine499 def: "Protein EMAL4_HUMAN with the residue 499 substituted with Phosphotyrosine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0011685 name: EMAL4_HUMAN-Phosphoserine502 def: "Protein EMAL4_HUMAN with the residue 502 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0011686 name: EMAL4_HUMAN-Phosphothreonine899 def: "Protein EMAL4_HUMAN with the residue 899 substituted with Phosphothreonine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0011687 name: ENOA_HUMAN-Phosphotyrosine44 def: "Protein ENOA_HUMAN with the residue 44 substituted with Phosphotyrosine" [UniProtKB:P06733] xref: UniProtKB:P06733 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:B0011688 name: ENOA_HUMAN-Phosphotyrosine57 def: "Protein ENOA_HUMAN with the residue 57 substituted with Phosphotyrosine" [UniProtKB:P06733] xref: UniProtKB:P06733 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:B0011689 name: ENOA_HUMAN-Phosphoserine63 def: "Protein ENOA_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:P06733] xref: UniProtKB:P06733 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:B0011690 name: ENOA_HUMAN-N6-acetyllysine71 def: "Protein ENOA_HUMAN with the residue 71 substituted with N6-acetyllysine" [UniProtKB:P06733] xref: UniProtKB:P06733 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:B0011691 name: ENOA_HUMAN-Phosphothreonine72 def: "Protein ENOA_HUMAN with the residue 72 substituted with Phosphothreonine" [UniProtKB:P06733] xref: UniProtKB:P06733 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:B0011692 name: ENOA_HUMAN-Phosphoserine263 def: "Protein ENOA_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:P06733] comment: By similarity xref: UniProtKB:P06733 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:B0011693 name: ENOA_HUMAN-Phosphotyrosine287 def: "Protein ENOA_HUMAN with the residue 287 substituted with Phosphotyrosine" [UniProtKB:P06733] xref: UniProtKB:P06733 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:B0011694 name: ENOG_HUMAN-Phosphotyrosine44 def: "Protein ENOG_HUMAN with the residue 44 substituted with Phosphotyrosine" [UniProtKB:P09104] xref: UniProtKB:P09104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006270 ! ENOG_HUMAN [Term] id: CCO:B0011695 name: ENOG_HUMAN-Phosphoserine80 def: "Protein ENOG_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:P09104] comment: By similarity xref: UniProtKB:P09104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006270 ! ENOG_HUMAN [Term] id: CCO:B0011696 name: EP15_HUMAN-Phosphoserine323 def: "Protein EP15_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:P42566] xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011697 name: EP15_HUMAN-Phosphoserine324 def: "Protein EP15_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:P42566] xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011698 name: EP15_HUMAN-Phosphoserine485 def: "Protein EP15_HUMAN with the residue 485 substituted with Phosphoserine" [UniProtKB:P42566] xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011699 name: EP15_HUMAN-Phosphoserine562 def: "Protein EP15_HUMAN with the residue 562 substituted with Phosphoserine" [UniProtKB:P42566] comment: By similarity xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011700 name: EP15_HUMAN-Phosphoserine563 def: "Protein EP15_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:P42566] comment: By similarity xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011701 name: EP15_HUMAN-Phosphothreonine779 def: "Protein EP15_HUMAN with the residue 779 substituted with Phosphothreonine" [UniProtKB:P42566] comment: By similarity xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011702 name: EP15_HUMAN-Phosphoserine814 def: "Protein EP15_HUMAN with the residue 814 substituted with Phosphoserine" [UniProtKB:P42566] xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011703 name: EP15_HUMAN-Phosphotyrosine849 def: "Protein EP15_HUMAN with the residue 849 substituted with Phosphotyrosine" [UniProtKB:P42566] comment: by EGFR; By similarity xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0011704 name: EP300_HUMAN-Omega-N-methylated arginine580 def: "Protein EP300_HUMAN with the residue 580 substituted with Omega-N-methylated arginine" [UniProtKB:Q09472] xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011705 name: EP300_HUMAN-Omega-N-methylated arginine604 def: "Protein EP300_HUMAN with the residue 604 substituted with Omega-N-methylated arginine" [UniProtKB:Q09472] xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011706 name: EP300_HUMAN-N6-acetyllysine1554 def: "Protein EP300_HUMAN with the residue 1554 substituted with N6-acetyllysine" [UniProtKB:Q09472] xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011707 name: EP300_HUMAN-N6-acetyllysine1555 def: "Protein EP300_HUMAN with the residue 1555 substituted with N6-acetyllysine" [UniProtKB:Q09472] xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011708 name: EP300_HUMAN-N6-acetyllysine1558 def: "Protein EP300_HUMAN with the residue 1558 substituted with N6-acetyllysine" [UniProtKB:Q09472] xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011709 name: EP300_HUMAN-N6-acetyllysine1560 def: "Protein EP300_HUMAN with the residue 1560 substituted with N6-acetyllysine" [UniProtKB:Q09472] xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011710 name: EP300_HUMAN-dimethylarginine2142 def: "Protein EP300_HUMAN with the residue 2142 substituted with dimethylarginine" [UniProtKB:Q09472] comment: alternate; xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011711 name: EP300_HUMAN-Citrulline2142 def: "Protein EP300_HUMAN with the residue 2142 substituted with Citrulline" [UniProtKB:Q09472] comment: alternate; xref: UniProtKB:Q09472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:B0011712 name: EP400_HUMAN-Phosphoserine736 def: "Protein EP400_HUMAN with the residue 736 substituted with Phosphoserine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0011713 name: EP400_HUMAN-Phosphoserine755 def: "Protein EP400_HUMAN with the residue 755 substituted with Phosphoserine" [UniProtKB:Q96L91] comment: By similarity xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0011714 name: EP400_HUMAN-Phosphoserine1547 def: "Protein EP400_HUMAN with the residue 1547 substituted with Phosphoserine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0011715 name: EPAS1_HUMAN-4-hydroxyproline405 def: "Protein EPAS1_HUMAN with the residue 405 substituted with 4-hydroxyproline" [UniProtKB:Q99814] comment: By similarity xref: UniProtKB:Q99814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006077 ! EPAS1_HUMAN [Term] id: CCO:B0011716 name: EPAS1_HUMAN-4-hydroxyproline531 def: "Protein EPAS1_HUMAN with the residue 531 substituted with 4-hydroxyproline" [UniProtKB:Q99814] comment: By similarity xref: UniProtKB:Q99814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006077 ! EPAS1_HUMAN [Term] id: CCO:B0011717 name: EPAS1_HUMAN-Phosphothreonine840 def: "Protein EPAS1_HUMAN with the residue 840 substituted with Phosphothreonine" [UniProtKB:Q99814] comment: By similarity xref: UniProtKB:Q99814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005559 ! histone acetyltransferase binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: transformation_of CCO:B0006077 ! EPAS1_HUMAN [Term] id: CCO:B0011718 name: EPAS1_HUMAN-3-hydroxyasparagine847 def: "Protein EPAS1_HUMAN with the residue 847 substituted with 3-hydroxyasparagine" [UniProtKB:Q99814] comment: By similarity xref: UniProtKB:Q99814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006077 ! EPAS1_HUMAN [Term] id: CCO:B0011719 name: EPC1_HUMAN-Phosphoserine357 def: "Protein EPC1_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q9H2F5] xref: UniProtKB:Q9H2F5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0005369 ! EPC1_HUMAN [Term] id: CCO:B0011720 name: EPHA2_HUMAN-Phosphoserine570 def: "Protein EPHA2_HUMAN with the residue 570 substituted with Phosphoserine" [UniProtKB:P29317] xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011721 name: EPHA2_HUMAN-Phosphotyrosine588 def: "Protein EPHA2_HUMAN with the residue 588 substituted with Phosphotyrosine" [UniProtKB:P29317] comment: by autocatalysis; Potential xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011722 name: EPHA2_HUMAN-Phosphotyrosine594 def: "Protein EPHA2_HUMAN with the residue 594 substituted with Phosphotyrosine" [UniProtKB:P29317] comment: by autocatalysis; xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011723 name: EPHA2_HUMAN-Phosphotyrosine772 def: "Protein EPHA2_HUMAN with the residue 772 substituted with Phosphotyrosine" [UniProtKB:P29317] comment: by autocatalysis; xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011724 name: EPHA2_HUMAN-Phosphoserine897 def: "Protein EPHA2_HUMAN with the residue 897 substituted with Phosphoserine" [UniProtKB:P29317] xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011725 name: EPHA2_HUMAN-Phosphothreonine898 def: "Protein EPHA2_HUMAN with the residue 898 substituted with Phosphothreonine" [UniProtKB:P29317] xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011726 name: EPHA2_HUMAN-Phosphoserine901 def: "Protein EPHA2_HUMAN with the residue 901 substituted with Phosphoserine" [UniProtKB:P29317] xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011727 name: EPHA2_HUMAN-Phosphotyrosine921 def: "Protein EPHA2_HUMAN with the residue 921 substituted with Phosphotyrosine" [UniProtKB:P29317] comment: by autocatalysis; Potential xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011728 name: EPHA2_HUMAN-Phosphotyrosine930 def: "Protein EPHA2_HUMAN with the residue 930 substituted with Phosphotyrosine" [UniProtKB:P29317] xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0011729 name: EPHB2_HUMAN-Phosphotyrosine596 def: "Protein EPHB2_HUMAN with the residue 596 substituted with Phosphotyrosine" [UniProtKB:P29323] comment: by autocatalysis; Potential xref: UniProtKB:P29323 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001568 ! EPHB2_HUMAN [Term] id: CCO:B0011730 name: EPHB2_HUMAN-Phosphotyrosine602 def: "Protein EPHB2_HUMAN with the residue 602 substituted with Phosphotyrosine" [UniProtKB:P29323] comment: by autocatalysis; Potential xref: UniProtKB:P29323 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001568 ! EPHB2_HUMAN [Term] id: CCO:B0011731 name: EPHB2_HUMAN-Phosphothreonine775 def: "Protein EPHB2_HUMAN with the residue 775 substituted with Phosphothreonine" [UniProtKB:P29323] xref: UniProtKB:P29323 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001342 ! transmembrane-ephrin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001568 ! EPHB2_HUMAN [Term] id: CCO:B0011732 name: EPHB2_HUMAN-Phosphotyrosine780 def: "Protein EPHB2_HUMAN with the residue 780 substituted with Phosphotyrosine" [UniProtKB:P29323] comment: by autocatalysis; Potential xref: UniProtKB:P29323 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001568 ! EPHB2_HUMAN [Term] id: CCO:B0011733 name: EPHB2_HUMAN-Phosphotyrosine930 def: "Protein EPHB2_HUMAN with the residue 930 substituted with Phosphotyrosine" [UniProtKB:P29323] comment: by autocatalysis; By similarity xref: UniProtKB:P29323 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001568 ! EPHB2_HUMAN [Term] id: CCO:B0011734 name: EPHB4_HUMAN-Phosphotyrosine590 def: "Protein EPHB4_HUMAN with the residue 590 substituted with Phosphotyrosine" [UniProtKB:P54760] comment: by autocatalysis; By similarity xref: UniProtKB:P54760 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005833 ! EPHB4_HUMAN [Term] id: CCO:B0011735 name: EPHB4_HUMAN-Phosphotyrosine596 def: "Protein EPHB4_HUMAN with the residue 596 substituted with Phosphotyrosine" [UniProtKB:P54760] comment: by autocatalysis; By similarity xref: UniProtKB:P54760 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005833 ! EPHB4_HUMAN [Term] id: CCO:B0011736 name: EPHB4_HUMAN-Phosphotyrosine774 def: "Protein EPHB4_HUMAN with the residue 774 substituted with Phosphotyrosine" [UniProtKB:P54760] comment: by autocatalysis; Potential xref: UniProtKB:P54760 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005833 ! EPHB4_HUMAN [Term] id: CCO:B0011737 name: EPHB4_HUMAN-Phosphotyrosine924 def: "Protein EPHB4_HUMAN with the residue 924 substituted with Phosphotyrosine" [UniProtKB:P54760] comment: by autocatalysis; By similarity xref: UniProtKB:P54760 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005833 ! EPHB4_HUMAN [Term] id: CCO:B0011738 name: ERBB2_HUMAN-Phosphotyrosine1139 def: "Protein ERBB2_HUMAN with the residue 1139 substituted with Phosphotyrosine" [UniProtKB:P04626] comment: by autocatalysis; By similarity xref: UniProtKB:P04626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005540 ! ERBB2_HUMAN [Term] id: CCO:B0011739 name: ERBB2_HUMAN-Phosphotyrosine1196 def: "Protein ERBB2_HUMAN with the residue 1196 substituted with Phosphotyrosine" [UniProtKB:P04626] comment: Potential xref: UniProtKB:P04626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005540 ! ERBB2_HUMAN [Term] id: CCO:B0011740 name: ERBB2_HUMAN-Phosphotyrosine1248 def: "Protein ERBB2_HUMAN with the residue 1248 substituted with Phosphotyrosine" [UniProtKB:P04626] comment: by autocatalysis; By similarity xref: UniProtKB:P04626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005540 ! ERBB2_HUMAN [Term] id: CCO:B0011741 name: ERBB4_HUMAN-Phosphotyrosine1162 def: "Protein ERBB4_HUMAN with the residue 1162 substituted with Phosphotyrosine" [UniProtKB:Q15303] comment: by autocatalysis; By similarity xref: UniProtKB:Q15303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:B0011742 name: ERBB4_HUMAN-Phosphotyrosine1188 def: "Protein ERBB4_HUMAN with the residue 1188 substituted with Phosphotyrosine" [UniProtKB:Q15303] comment: by autocatalysis; By similarity xref: UniProtKB:Q15303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:B0011743 name: ERBB4_HUMAN-Phosphotyrosine1258 def: "Protein ERBB4_HUMAN with the residue 1258 substituted with Phosphotyrosine" [UniProtKB:Q15303] comment: by autocatalysis; By similarity xref: UniProtKB:Q15303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:B0011744 name: ERBB4_HUMAN-Phosphotyrosine1284 def: "Protein ERBB4_HUMAN with the residue 1284 substituted with Phosphotyrosine" [UniProtKB:Q15303] comment: by autocatalysis; By similarity xref: UniProtKB:Q15303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:B0011745 name: ERCC5_HUMAN-Phosphoserine156 def: "Protein ERCC5_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011746 name: ERCC5_HUMAN-Phosphoserine157 def: "Protein ERCC5_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011747 name: ERCC5_HUMAN-Phosphothreonine338 def: "Protein ERCC5_HUMAN with the residue 338 substituted with Phosphothreonine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011748 name: ERCC5_HUMAN-Phosphoserine341 def: "Protein ERCC5_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011749 name: ERCC5_HUMAN-Phosphoserine355 def: "Protein ERCC5_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011750 name: ERCC5_HUMAN-Phosphoserine356 def: "Protein ERCC5_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011751 name: ERCC5_HUMAN-Phosphoserine357 def: "Protein ERCC5_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011752 name: ERCC5_HUMAN-Phosphoserine384 def: "Protein ERCC5_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000087 ! bubble DNA binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000917 ! endodeoxyribonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000279 ! holo TFIIH complex relationship: located_in CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011753 name: ERCC5_HUMAN-Phosphoserine428 def: "Protein ERCC5_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011754 name: ERCC5_HUMAN-Phosphoserine526 def: "Protein ERCC5_HUMAN with the residue 526 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011755 name: ERCC5_HUMAN-Phosphoserine563 def: "Protein ERCC5_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011756 name: ERCC5_HUMAN-Phosphoserine705 def: "Protein ERCC5_HUMAN with the residue 705 substituted with Phosphoserine" [UniProtKB:P28715] comment: By similarity xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011757 name: ERCC5_HUMAN-Phosphoserine724 def: "Protein ERCC5_HUMAN with the residue 724 substituted with Phosphoserine" [UniProtKB:P28715] xref: UniProtKB:P28715 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:B0011758 name: ERF_HUMAN-Phosphoserine21 def: "Protein ERF_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0011759 name: ERF_HUMAN-Phosphoserine185 def: "Protein ERF_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0011760 name: ERF_HUMAN-Phosphoserine187 def: "Protein ERF_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0011761 name: ERF_HUMAN-Phosphoserine190 def: "Protein ERF_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0011762 name: ERF_HUMAN-Phosphothreonine526 def: "Protein ERF_HUMAN with the residue 526 substituted with Phosphothreonine" [UniProtKB:P50548] comment: by MAPK1; xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0011763 name: ERF_HUMAN-Phosphoserine531 def: "Protein ERF_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0011764 name: ESCO1_HUMAN-Phosphoserine31 def: "Protein ESCO1_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q5FWF5] xref: UniProtKB:Q5FWF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001848 ! ESCO1_HUMAN [Term] id: CCO:B0011765 name: ESCO2_HUMAN-Phosphoserine29 def: "Protein ESCO2_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q56NI9] xref: UniProtKB:Q56NI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001841 ! ESCO2_HUMAN [Term] id: CCO:B0011766 name: ESPL1_HUMAN-Phosphoserine1126 def: "Protein ESPL1_HUMAN with the residue 1126 substituted with Phosphoserine" [UniProtKB:Q14674] xref: UniProtKB:Q14674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001787 ! ESPL1_HUMAN [Term] id: CCO:B0011767 name: ESPL1_HUMAN-Phosphoserine1508 def: "Protein ESPL1_HUMAN with the residue 1508 substituted with Phosphoserine" [UniProtKB:Q14674] xref: UniProtKB:Q14674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0001787 ! ESPL1_HUMAN [Term] id: CCO:B0011768 name: ESR1_HUMAN-Phosphoserine104 def: "Protein ESR1_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:P03372] comment: by CDK2; xref: UniProtKB:P03372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:B0011769 name: ESR1_HUMAN-Phosphoserine106 def: "Protein ESR1_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:P03372] comment: by CDK2; xref: UniProtKB:P03372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:B0011770 name: ESR1_HUMAN-Phosphoserine118 def: "Protein ESR1_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:P03372] xref: UniProtKB:P03372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:B0011771 name: ESR1_HUMAN-Phosphoserine167 def: "Protein ESR1_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:P03372] comment: by CK2; xref: UniProtKB:P03372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:B0011772 name: ESR1_HUMAN-Phosphotyrosine537 def: "Protein ESR1_HUMAN with the residue 537 substituted with Phosphotyrosine" [UniProtKB:P03372] comment: by Tyr-kinases; xref: UniProtKB:P03372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:B0011773 name: EVI5_HUMAN-Phosphoserine477 def: "Protein EVI5_HUMAN with the residue 477 substituted with Phosphoserine" [UniProtKB:O60447] xref: UniProtKB:O60447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001408 ! EVI5_HUMAN [Term] id: CCO:B0011774 name: EVI5_HUMAN-Phosphoserine776 def: "Protein EVI5_HUMAN with the residue 776 substituted with Phosphoserine" [UniProtKB:O60447] comment: By similarity xref: UniProtKB:O60447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001408 ! EVI5_HUMAN [Term] id: CCO:B0011775 name: EVI5_HUMAN-Phosphoserine778 def: "Protein EVI5_HUMAN with the residue 778 substituted with Phosphoserine" [UniProtKB:O60447] comment: By similarity xref: UniProtKB:O60447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001408 ! EVI5_HUMAN [Term] id: CCO:B0011776 name: EWS_HUMAN-Phosphoserine266 def: "Protein EWS_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q01844] comment: by PKC; By similarity xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011777 name: EWS_HUMAN-Asymmetric dimethylarginine300 def: "Protein EWS_HUMAN with the residue 300 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011778 name: EWS_HUMAN-Asymmetric dimethylarginine302 def: "Protein EWS_HUMAN with the residue 302 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011779 name: EWS_HUMAN-Asymmetric dimethylarginine304 def: "Protein EWS_HUMAN with the residue 304 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011780 name: EWS_HUMAN-Asymmetric dimethylarginine309 def: "Protein EWS_HUMAN with the residue 309 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011781 name: EWS_HUMAN-Asymmetric dimethylarginine314 def: "Protein EWS_HUMAN with the residue 314 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011782 name: EWS_HUMAN-Asymmetric dimethylarginine317 def: "Protein EWS_HUMAN with the residue 317 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011783 name: EWS_HUMAN-Asymmetric dimethylarginine321 def: "Protein EWS_HUMAN with the residue 321 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011784 name: EWS_HUMAN-Asymmetric dimethylarginine455 def: "Protein EWS_HUMAN with the residue 455 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011785 name: EWS_HUMAN-Asymmetric dimethylarginine464 def: "Protein EWS_HUMAN with the residue 464 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011786 name: EWS_HUMAN-dimethylarginine471 def: "Protein EWS_HUMAN with the residue 471 substituted with dimethylarginine" [UniProtKB:Q01844] comment: alternate; xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011787 name: EWS_HUMAN-Omega-N-methylarginine471 def: "Protein EWS_HUMAN with the residue 471 substituted with Omega-N-methylarginine" [UniProtKB:Q01844] comment: alternate; xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011788 name: EWS_HUMAN-Asymmetric dimethylarginine490 def: "Protein EWS_HUMAN with the residue 490 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011789 name: EWS_HUMAN-Asymmetric dimethylarginine494 def: "Protein EWS_HUMAN with the residue 494 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011790 name: EWS_HUMAN-Asymmetric dimethylarginine500 def: "Protein EWS_HUMAN with the residue 500 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011791 name: EWS_HUMAN-Asymmetric dimethylarginine503 def: "Protein EWS_HUMAN with the residue 503 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011792 name: EWS_HUMAN-Asymmetric dimethylarginine506 def: "Protein EWS_HUMAN with the residue 506 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011793 name: EWS_HUMAN-Asymmetric dimethylarginine563 def: "Protein EWS_HUMAN with the residue 563 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011794 name: EWS_HUMAN-Asymmetric dimethylarginine565 def: "Protein EWS_HUMAN with the residue 565 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011795 name: EWS_HUMAN-Asymmetric dimethylarginine572 def: "Protein EWS_HUMAN with the residue 572 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011796 name: EWS_HUMAN-Asymmetric dimethylarginine575 def: "Protein EWS_HUMAN with the residue 575 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011797 name: EWS_HUMAN-Asymmetric dimethylarginine581 def: "Protein EWS_HUMAN with the residue 581 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011798 name: EWS_HUMAN-Asymmetric dimethylarginine589 def: "Protein EWS_HUMAN with the residue 589 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000709 ! cell surface relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011799 name: EWS_HUMAN-Asymmetric dimethylarginine592 def: "Protein EWS_HUMAN with the residue 592 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011800 name: EWS_HUMAN-Asymmetric dimethylarginine596 def: "Protein EWS_HUMAN with the residue 596 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011801 name: EWS_HUMAN-Asymmetric dimethylarginine600 def: "Protein EWS_HUMAN with the residue 600 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011802 name: EWS_HUMAN-Asymmetric dimethylarginine603 def: "Protein EWS_HUMAN with the residue 603 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011803 name: EWS_HUMAN-Asymmetric dimethylarginine607 def: "Protein EWS_HUMAN with the residue 607 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011804 name: EWS_HUMAN-Asymmetric dimethylarginine615 def: "Protein EWS_HUMAN with the residue 615 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011805 name: EWS_HUMAN-Asymmetric dimethylarginine633 def: "Protein EWS_HUMAN with the residue 633 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011806 name: EWS_HUMAN-Asymmetric dimethylarginine636 def: "Protein EWS_HUMAN with the residue 636 substituted with Asymmetric dimethylarginine" [UniProtKB:Q01844] xref: UniProtKB:Q01844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:B0011807 name: EXO1_HUMAN-Phosphoserine598 def: "Protein EXO1_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q9UQ84] xref: UniProtKB:Q9UQ84 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002240 ! EXO1_HUMAN [Term] id: CCO:B0011808 name: EXO1_HUMAN-Phosphoserine714 def: "Protein EXO1_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:Q9UQ84] xref: UniProtKB:Q9UQ84 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002240 ! EXO1_HUMAN [Term] id: CCO:B0011809 name: EXOC8_HUMAN-Phosphoserine19 def: "Protein EXOC8_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q8IYI6] xref: UniProtKB:Q8IYI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0005255 ! EXOC8_HUMAN [Term] id: CCO:B0011810 name: EXOS3_HUMAN-N-acetylalanine2 def: "Protein EXOS3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9NQT5] xref: UniProtKB:Q9NQT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000034 ! 3'-5'-exoribonuclease activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000032 ! nuclear exosome (RNase complex) relationship: located_in CCO:C0000033 ! cytoplasmic exosome (RNase complex) relationship: located_in CCO:C0000034 ! exosome (RNase complex) relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005557 ! EXOS3_HUMAN [Term] id: CCO:B0011811 name: EXOS4_HUMAN-N-acetylalanine2 def: "Protein EXOS4_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9NPD3] xref: UniProtKB:Q9NPD3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000034 ! 3'-5'-exoribonuclease activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000034 ! exosome (RNase complex) relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005554 ! EXOS4_HUMAN [Term] id: CCO:B0011812 name: EXOS5_HUMAN-Phosphoserine20 def: "Protein EXOS5_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q9NQT4] xref: UniProtKB:Q9NQT4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000034 ! 3'-5'-exoribonuclease activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000034 ! exosome (RNase complex) relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005555 ! EXOS5_HUMAN [Term] id: CCO:B0011813 name: EXOS5_HUMAN-Phosphoserine27 def: "Protein EXOS5_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q9NQT4] comment: By similarity xref: UniProtKB:Q9NQT4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005555 ! EXOS5_HUMAN [Term] id: CCO:B0011814 name: FACD2_HUMAN-Phosphoserine167 def: "Protein FACD2_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011815 name: FACD2_HUMAN-Phosphoserine178 def: "Protein FACD2_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011816 name: FACD2_HUMAN-Phosphoserine222 def: "Protein FACD2_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q9BXW9] comment: by ATM; xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011817 name: FACD2_HUMAN-Phosphoserine592 def: "Protein FACD2_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011818 name: FACD2_HUMAN-Phosphothreonine596 def: "Protein FACD2_HUMAN with the residue 596 substituted with Phosphothreonine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011819 name: FACD2_HUMAN-Phosphoserine717 def: "Protein FACD2_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011820 name: FACD2_HUMAN-Phosphoserine1401 def: "Protein FACD2_HUMAN with the residue 1401 substituted with Phosphoserine" [UniProtKB:Q9BXW9] comment: by ATM; Probable xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011821 name: FACD2_HUMAN-Phosphoserine1404 def: "Protein FACD2_HUMAN with the residue 1404 substituted with Phosphoserine" [UniProtKB:Q9BXW9] comment: by ATM; xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011822 name: FACD2_HUMAN-Phosphoserine1412 def: "Protein FACD2_HUMAN with the residue 1412 substituted with Phosphoserine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011823 name: FACD2_HUMAN-Phosphoserine1418 def: "Protein FACD2_HUMAN with the residue 1418 substituted with Phosphoserine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0011824 name: FAK1_HUMAN-N-acetylalanine2 def: "Protein FAK1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011825 name: FAK1_HUMAN-Phosphotyrosine397 def: "Protein FAK1_HUMAN with the residue 397 substituted with Phosphotyrosine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011826 name: FAK1_HUMAN-Phosphotyrosine407 def: "Protein FAK1_HUMAN with the residue 407 substituted with Phosphotyrosine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011827 name: FAK1_HUMAN-Phosphotyrosine576 def: "Protein FAK1_HUMAN with the residue 576 substituted with Phosphotyrosine" [UniProtKB:Q05397] comment: by autocatalysis; xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011828 name: FAK1_HUMAN-Phosphotyrosine577 def: "Protein FAK1_HUMAN with the residue 577 substituted with Phosphotyrosine" [UniProtKB:Q05397] comment: by autocatalysis; xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011829 name: FAK1_HUMAN-Phosphoserine722 def: "Protein FAK1_HUMAN with the residue 722 substituted with Phosphoserine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011830 name: FAK1_HUMAN-Phosphoserine840 def: "Protein FAK1_HUMAN with the residue 840 substituted with Phosphoserine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011831 name: FAK1_HUMAN-Phosphoserine843 def: "Protein FAK1_HUMAN with the residue 843 substituted with Phosphoserine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011832 name: FAK1_HUMAN-Phosphotyrosine861 def: "Protein FAK1_HUMAN with the residue 861 substituted with Phosphotyrosine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011833 name: FAK1_HUMAN-Phosphoserine910 def: "Protein FAK1_HUMAN with the residue 910 substituted with Phosphoserine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011834 name: FAK1_HUMAN-Phosphotyrosine925 def: "Protein FAK1_HUMAN with the residue 925 substituted with Phosphotyrosine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0011835 name: FAK2_HUMAN-Phosphoserine375 def: "Protein FAK2_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:Q14289] xref: UniProtKB:Q14289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005846 ! FAK2_HUMAN [Term] id: CCO:B0011836 name: FAK2_HUMAN-Phosphotyrosine402 def: "Protein FAK2_HUMAN with the residue 402 substituted with Phosphotyrosine" [UniProtKB:Q14289] xref: UniProtKB:Q14289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005846 ! FAK2_HUMAN [Term] id: CCO:B0011837 name: FAK2_HUMAN-Phosphotyrosine579 def: "Protein FAK2_HUMAN with the residue 579 substituted with Phosphotyrosine" [UniProtKB:Q14289] comment: by autocatalysis; xref: UniProtKB:Q14289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005846 ! FAK2_HUMAN [Term] id: CCO:B0011838 name: FAK2_HUMAN-Phosphotyrosine580 def: "Protein FAK2_HUMAN with the residue 580 substituted with Phosphotyrosine" [UniProtKB:Q14289] xref: UniProtKB:Q14289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005846 ! FAK2_HUMAN [Term] id: CCO:B0011839 name: FAK2_HUMAN-Phosphotyrosine881 def: "Protein FAK2_HUMAN with the residue 881 substituted with Phosphotyrosine" [UniProtKB:Q14289] comment: By similarity xref: UniProtKB:Q14289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005846 ! FAK2_HUMAN [Term] id: CCO:B0011840 name: FANCA_HUMAN-Phosphoserine849 def: "Protein FANCA_HUMAN with the residue 849 substituted with Phosphoserine" [UniProtKB:O15360] xref: UniProtKB:O15360 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005323 ! FANCA_HUMAN [Term] id: CCO:B0011841 name: FANCA_HUMAN-Phosphoserine850 def: "Protein FANCA_HUMAN with the residue 850 substituted with Phosphoserine" [UniProtKB:O15360] xref: UniProtKB:O15360 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005323 ! FANCA_HUMAN [Term] id: CCO:B0011842 name: FANCA_HUMAN-Phosphoserine858 def: "Protein FANCA_HUMAN with the residue 858 substituted with Phosphoserine" [UniProtKB:O15360] xref: UniProtKB:O15360 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005323 ! FANCA_HUMAN [Term] id: CCO:B0011843 name: FANCA_HUMAN-Phosphoserine1449 def: "Protein FANCA_HUMAN with the residue 1449 substituted with Phosphoserine" [UniProtKB:O15360] xref: UniProtKB:O15360 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005323 ! FANCA_HUMAN [Term] id: CCO:B0011844 name: FANCI_HUMAN-Phosphoserine407 def: "Protein FANCI_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q9NVI1] xref: UniProtKB:Q9NVI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002170 ! FANCI_HUMAN [Term] id: CCO:B0011845 name: FANCI_HUMAN-Phosphoserine556 def: "Protein FANCI_HUMAN with the residue 556 substituted with Phosphoserine" [UniProtKB:Q9NVI1] comment: By similarity xref: UniProtKB:Q9NVI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0002170 ! FANCI_HUMAN [Term] id: CCO:B0011846 name: FANCI_HUMAN-Phosphoserine730 def: "Protein FANCI_HUMAN with the residue 730 substituted with Phosphoserine" [UniProtKB:Q9NVI1] xref: UniProtKB:Q9NVI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002170 ! FANCI_HUMAN [Term] id: CCO:B0011847 name: FANCI_HUMAN-Phosphothreonine952 def: "Protein FANCI_HUMAN with the residue 952 substituted with Phosphothreonine" [UniProtKB:Q9NVI1] xref: UniProtKB:Q9NVI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002170 ! FANCI_HUMAN [Term] id: CCO:B0011848 name: FANCI_HUMAN-Phosphoserine1121 def: "Protein FANCI_HUMAN with the residue 1121 substituted with Phosphoserine" [UniProtKB:Q9NVI1] xref: UniProtKB:Q9NVI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002170 ! FANCI_HUMAN [Term] id: CCO:B0011849 name: FANCJ_HUMAN-Phosphoserine990 def: "Protein FANCJ_HUMAN with the residue 990 substituted with Phosphoserine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0011850 name: FANCJ_HUMAN-Phosphoserine1032 def: "Protein FANCJ_HUMAN with the residue 1032 substituted with Phosphoserine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0011851 name: FBRL_HUMAN-Asymmetric dimethylarginine8 def: "Protein FBRL_HUMAN with the residue 8 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011852 name: FBRL_HUMAN-Asymmetric dimethylarginine15 def: "Protein FBRL_HUMAN with the residue 15 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011853 name: FBRL_HUMAN-Asymmetric dimethylarginine21 def: "Protein FBRL_HUMAN with the residue 21 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011854 name: FBRL_HUMAN-Asymmetric dimethylarginine24 def: "Protein FBRL_HUMAN with the residue 24 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011855 name: FBRL_HUMAN-Asymmetric dimethylarginine27 def: "Protein FBRL_HUMAN with the residue 27 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011856 name: FBRL_HUMAN-Asymmetric dimethylarginine34 def: "Protein FBRL_HUMAN with the residue 34 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011857 name: FBRL_HUMAN-Asymmetric dimethylarginine36 def: "Protein FBRL_HUMAN with the residue 36 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011858 name: FBRL_HUMAN-Asymmetric dimethylarginine41 def: "Protein FBRL_HUMAN with the residue 41 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011859 name: FBRL_HUMAN-Asymmetric dimethylarginine43 def: "Protein FBRL_HUMAN with the residue 43 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011860 name: FBRL_HUMAN-Asymmetric dimethylarginine45 def: "Protein FBRL_HUMAN with the residue 45 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011861 name: FBRL_HUMAN-Asymmetric dimethylarginine59 def: "Protein FBRL_HUMAN with the residue 59 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011862 name: FBRL_HUMAN-Asymmetric dimethylarginine70 def: "Protein FBRL_HUMAN with the residue 70 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011863 name: FBRL_HUMAN-Asymmetric dimethylarginine72 def: "Protein FBRL_HUMAN with the residue 72 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011864 name: FBRL_HUMAN-Asymmetric dimethylarginine74 def: "Protein FBRL_HUMAN with the residue 74 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011865 name: FBRL_HUMAN-Asymmetric dimethylarginine78 def: "Protein FBRL_HUMAN with the residue 78 substituted with Asymmetric dimethylarginine" [UniProtKB:P22087] comment: By similarity xref: UniProtKB:P22087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:B0011866 name: FBX43_HUMAN-Phosphoserine76 def: "Protein FBX43_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q4G163] comment: Probable xref: UniProtKB:Q4G163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001835 ! FBX43_HUMAN [Term] id: CCO:B0011867 name: FBX43_HUMAN-Phosphothreonine234 def: "Protein FBX43_HUMAN with the residue 234 substituted with Phosphothreonine" [UniProtKB:Q4G163] xref: UniProtKB:Q4G163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001835 ! FBX43_HUMAN [Term] id: CCO:B0011868 name: FBX43_HUMAN-Phosphoserine334 def: "Protein FBX43_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q4G163] comment: Probable xref: UniProtKB:Q4G163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001835 ! FBX43_HUMAN [Term] id: CCO:B0011869 name: FBX43_HUMAN-Phosphotyrosine503 def: "Protein FBX43_HUMAN with the residue 503 substituted with Phosphotyrosine" [UniProtKB:Q4G163] comment: By similarity xref: UniProtKB:Q4G163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001835 ! FBX43_HUMAN [Term] id: CCO:B0011870 name: FBX4_HUMAN-Phosphoserine12 def: "Protein FBX4_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q9UKT5] xref: UniProtKB:Q9UKT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005441 ! FBX4_HUMAN [Term] id: CCO:B0011871 name: FBX4_HUMAN-Phosphoserine238 def: "Protein FBX4_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q9UKT5] xref: UniProtKB:Q9UKT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005441 ! FBX4_HUMAN [Term] id: CCO:B0011872 name: FBX4_HUMAN-Phosphothreonine239 def: "Protein FBX4_HUMAN with the residue 239 substituted with Phosphothreonine" [UniProtKB:Q9UKT5] xref: UniProtKB:Q9UKT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005441 ! FBX4_HUMAN [Term] id: CCO:B0011873 name: FBX4_HUMAN-Phosphothreonine240 def: "Protein FBX4_HUMAN with the residue 240 substituted with Phosphothreonine" [UniProtKB:Q9UKT5] xref: UniProtKB:Q9UKT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005441 ! FBX4_HUMAN [Term] id: CCO:B0011874 name: FBXW7_HUMAN-Phosphoserine26 def: "Protein FBXW7_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q969H0] xref: UniProtKB:Q969H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005654 ! FBXW7_HUMAN [Term] id: CCO:B0011875 name: FEZ1_HUMAN-Phosphoserine58 def: "Protein FEZ1_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:Q99689] comment: By similarity xref: UniProtKB:Q99689 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005393 ! FEZ1_HUMAN [Term] id: CCO:B0011876 name: FGF1_HUMAN-N-acetylalanine2 def: "Protein FGF1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P05230] xref: UniProtKB:P05230 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0001486 ! FGF1_HUMAN [Term] id: CCO:B0011877 name: FGFR1_HUMAN-Phosphotyrosine654 def: "Protein FGFR1_HUMAN with the residue 654 substituted with Phosphotyrosine" [UniProtKB:P11362] comment: by autocatalysis; By similarity xref: UniProtKB:P11362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005868 ! FGFR1_HUMAN [Term] id: CCO:B0011878 name: FGFR1_HUMAN-Phosphotyrosine766 def: "Protein FGFR1_HUMAN with the residue 766 substituted with Phosphotyrosine" [UniProtKB:P11362] comment: by autocatalysis; xref: UniProtKB:P11362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005868 ! FGFR1_HUMAN [Term] id: CCO:B0011879 name: FGFR2_HUMAN-Phosphotyrosine657 def: "Protein FGFR2_HUMAN with the residue 657 substituted with Phosphotyrosine" [UniProtKB:P21802] comment: by autocatalysis; By similarity xref: UniProtKB:P21802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001344 ! fibroblast growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005381 ! FGFR2_HUMAN [Term] id: CCO:B0011880 name: FGFR3_HUMAN-Phosphotyrosine648 def: "Protein FGFR3_HUMAN with the residue 648 substituted with Phosphotyrosine" [UniProtKB:P22607] comment: by autocatalysis; By similarity xref: UniProtKB:P22607 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:B0011881 name: FHIT_HUMAN-Phosphotyrosine114 def: "Protein FHIT_HUMAN with the residue 114 substituted with Phosphotyrosine" [UniProtKB:P49789] comment: by SRC; xref: UniProtKB:P49789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001636 ! FHIT_HUMAN [Term] id: CCO:B0011882 name: FHIT_HUMAN-Phosphotyrosine145 def: "Protein FHIT_HUMAN with the residue 145 substituted with Phosphotyrosine" [UniProtKB:P49789] xref: UniProtKB:P49789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001636 ! FHIT_HUMAN [Term] id: CCO:B0011883 name: FL2D_HUMAN-Phosphoserine244 def: "Protein FL2D_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:Q15007] xref: UniProtKB:Q15007 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001798 ! FL2D_HUMAN [Term] id: CCO:B0011884 name: FL2D_HUMAN-Phosphoserine306 def: "Protein FL2D_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q15007] xref: UniProtKB:Q15007 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0001798 ! FL2D_HUMAN [Term] id: CCO:B0011885 name: FNBP1_HUMAN-Phosphothreonine294 def: "Protein FNBP1_HUMAN with the residue 294 substituted with Phosphothreonine" [UniProtKB:Q96RU3] xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0011886 name: FNBP1_HUMAN-Phosphoserine296 def: "Protein FNBP1_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q96RU3] xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0011887 name: FNBP1_HUMAN-Phosphoserine299 def: "Protein FNBP1_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:Q96RU3] xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0011888 name: FNBP1_HUMAN-Phosphotyrosine522 def: "Protein FNBP1_HUMAN with the residue 522 substituted with Phosphotyrosine" [UniProtKB:Q96RU3] xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0011889 name: FOXN3_HUMAN-Phosphoserine85 def: "Protein FOXN3_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:O00409] comment: By similarity xref: UniProtKB:O00409 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001347 ! FOXN3_HUMAN [Term] id: CCO:B0011890 name: FOXO4_HUMAN-Phosphothreonine32 def: "Protein FOXO4_HUMAN with the residue 32 substituted with Phosphothreonine" [UniProtKB:P98177] comment: by PKB/AKT1; xref: UniProtKB:P98177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001706 ! FOXO4_HUMAN [Term] id: CCO:B0011891 name: FOXO4_HUMAN-Phosphoserine197 def: "Protein FOXO4_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:P98177] comment: by PKB/AKT1; xref: UniProtKB:P98177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001706 ! FOXO4_HUMAN [Term] id: CCO:B0011892 name: FOXO4_HUMAN-Phosphoserine262 def: "Protein FOXO4_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:P98177] comment: by PKB/AKT1; xref: UniProtKB:P98177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001706 ! FOXO4_HUMAN [Term] id: CCO:B0011893 name: FRAP_HUMAN-Phosphoserine2478 def: "Protein FRAP_HUMAN with the residue 2478 substituted with Phosphoserine" [UniProtKB:P42345] xref: UniProtKB:P42345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001611 ! FRAP_HUMAN [Term] id: CCO:B0011894 name: FRAP_HUMAN-Phosphoserine2481 def: "Protein FRAP_HUMAN with the residue 2481 substituted with Phosphoserine" [UniProtKB:P42345] xref: UniProtKB:P42345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001611 ! FRAP_HUMAN [Term] id: CCO:B0011895 name: FRIL_HUMAN-N-acetylserine2 def: "Protein FRIL_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P02792] xref: UniProtKB:P02792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001778 ! ferric iron binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000525 ! ferritin complex relationship: transformation_of CCO:B0006192 ! FRIL_HUMAN [Term] id: CCO:B0011896 name: FRK_HUMAN-Phosphotyrosine387 def: "Protein FRK_HUMAN with the residue 387 substituted with Phosphotyrosine" [UniProtKB:P42685] comment: by autocatalysis; By similarity xref: UniProtKB:P42685 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001613 ! FRK_HUMAN [Term] id: CCO:B0011897 name: FRK_HUMAN-Phosphotyrosine497 def: "Protein FRK_HUMAN with the residue 497 substituted with Phosphotyrosine" [UniProtKB:P42685] xref: UniProtKB:P42685 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001613 ! FRK_HUMAN [Term] id: CCO:B0011898 name: FRMD6_HUMAN-Phosphoserine522 def: "Protein FRMD6_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q96NE9] comment: By similarity xref: UniProtKB:Q96NE9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005267 ! FRMD6_HUMAN [Term] id: CCO:B0011899 name: FRMD6_HUMAN-Phosphoserine525 def: "Protein FRMD6_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q96NE9] comment: By similarity xref: UniProtKB:Q96NE9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005267 ! FRMD6_HUMAN [Term] id: CCO:B0011900 name: FUMH_HUMAN-N6-acetyllysine66 def: "Protein FUMH_HUMAN with the residue 66 substituted with N6-acetyllysine" [UniProtKB:P07954] comment: By similarity xref: UniProtKB:P07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001496 ! FUMH_HUMAN [Term] id: CCO:B0011901 name: FUMH_HUMAN-N6-acetyllysine115 def: "Protein FUMH_HUMAN with the residue 115 substituted with N6-acetyllysine" [UniProtKB:P07954] comment: By similarity xref: UniProtKB:P07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001496 ! FUMH_HUMAN [Term] id: CCO:B0011902 name: FUMH_HUMAN-N6-acetyllysine477 def: "Protein FUMH_HUMAN with the residue 477 substituted with N6-acetyllysine" [UniProtKB:P07954] comment: By similarity xref: UniProtKB:P07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001496 ! FUMH_HUMAN [Term] id: CCO:B0011903 name: FXR1_HUMAN-Phosphoserine406 def: "Protein FXR1_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:P51114] xref: UniProtKB:P51114 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006140 ! FXR1_HUMAN [Term] id: CCO:B0011904 name: FXR1_HUMAN-Phosphoserine409 def: "Protein FXR1_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:P51114] xref: UniProtKB:P51114 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006140 ! FXR1_HUMAN [Term] id: CCO:B0011905 name: FXR1_HUMAN-Omega-N-methylated arginine445 def: "Protein FXR1_HUMAN with the residue 445 substituted with Omega-N-methylated arginine" [UniProtKB:P51114] xref: UniProtKB:P51114 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000410 ! polysome relationship: transformation_of CCO:B0006140 ! FXR1_HUMAN [Term] id: CCO:B0011906 name: FXR1_HUMAN-Phosphotyrosine477 def: "Protein FXR1_HUMAN with the residue 477 substituted with Phosphotyrosine" [UniProtKB:P51114] xref: UniProtKB:P51114 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006140 ! FXR1_HUMAN [Term] id: CCO:B0011907 name: FYN_HUMAN-Phosphothreonine12 def: "Protein FYN_HUMAN with the residue 12 substituted with Phosphothreonine" [UniProtKB:P06241] comment: by PKC; By similarity xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0011908 name: FYN_HUMAN-Phosphoserine21 def: "Protein FYN_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P06241] xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0011909 name: FYN_HUMAN-Phosphotyrosine420 def: "Protein FYN_HUMAN with the residue 420 substituted with Phosphotyrosine" [UniProtKB:P06241] comment: by autocatalysis; xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0011910 name: FYN_HUMAN-Phosphotyrosine531 def: "Protein FYN_HUMAN with the residue 531 substituted with Phosphotyrosine" [UniProtKB:P06241] xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0011911 name: FZR_HUMAN-Phosphoserine36 def: "Protein FZR_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0011912 name: FZR_HUMAN-Phosphoserine151 def: "Protein FZR_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0011913 name: G3P_HUMAN-Phosphotyrosine42 def: "Protein G3P_HUMAN with the residue 42 substituted with Phosphotyrosine" [UniProtKB:P04406] xref: UniProtKB:P04406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000784 ! glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002279 ! glyceraldehyde-3-phosphate dehydrogenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:B0011914 name: G3P_HUMAN-Phosphoserine83 def: "Protein G3P_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P04406] xref: UniProtKB:P04406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:B0011915 name: G3P_HUMAN-Phosphothreonine211 def: "Protein G3P_HUMAN with the residue 211 substituted with Phosphothreonine" [UniProtKB:P04406] comment: By similarity xref: UniProtKB:P04406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:B0011916 name: GA2L1_HUMAN-Phosphoserine384 def: "Protein GA2L1_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0011917 name: GAB2_HUMAN-Phosphotyrosine266 def: "Protein GAB2_HUMAN with the residue 266 substituted with Phosphotyrosine" [UniProtKB:Q9UQC2] xref: UniProtKB:Q9UQC2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005924 ! GAB2_HUMAN [Term] id: CCO:B0011918 name: GAB2_HUMAN-Phosphoserine405 def: "Protein GAB2_HUMAN with the residue 405 substituted with Phosphoserine" [UniProtKB:Q9UQC2] comment: By similarity xref: UniProtKB:Q9UQC2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005924 ! GAB2_HUMAN [Term] id: CCO:B0011919 name: GABR1_HUMAN-Phosphothreonine930 def: "Protein GABR1_HUMAN with the residue 930 substituted with Phosphothreonine" [UniProtKB:Q9UBS5] comment: By similarity xref: UniProtKB:Q9UBS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006317 ! GABR1_HUMAN [Term] id: CCO:B0011920 name: GAK_HUMAN-Phosphoserine829 def: "Protein GAK_HUMAN with the residue 829 substituted with Phosphoserine" [UniProtKB:O14976] comment: By similarity xref: UniProtKB:O14976 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0001364 ! GAK_HUMAN [Term] id: CCO:B0011921 name: GBF1_HUMAN-Phosphoserine1773 def: "Protein GBF1_HUMAN with the residue 1773 substituted with Phosphoserine" [UniProtKB:Q92538] xref: UniProtKB:Q92538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0005359 ! GBF1_HUMAN [Term] id: CCO:B0011922 name: GBF1_HUMAN-Phosphoserine1784 def: "Protein GBF1_HUMAN with the residue 1784 substituted with Phosphoserine" [UniProtKB:Q92538] xref: UniProtKB:Q92538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005359 ! GBF1_HUMAN [Term] id: CCO:B0011923 name: GBLP_HUMAN-N-acetylthreonine2 def: "Protein GBLP_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P63244] xref: UniProtKB:P63244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005739 ! GBLP_HUMAN [Term] id: CCO:B0011924 name: GBLP_HUMAN-Phosphotyrosine228 def: "Protein GBLP_HUMAN with the residue 228 substituted with Phosphotyrosine" [UniProtKB:P63244] xref: UniProtKB:P63244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005739 ! GBLP_HUMAN [Term] id: CCO:B0011925 name: GCNL2_HUMAN-Phosphotyrosine734 def: "Protein GCNL2_HUMAN with the residue 734 substituted with Phosphotyrosine" [UniProtKB:Q92830] xref: UniProtKB:Q92830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005647 ! GCNL2_HUMAN [Term] id: CCO:B0011928 name: GEMI_HUMAN-Phosphoserine64 def: "Protein GEMI_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:O75496] xref: UniProtKB:O75496 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001432 ! GEMI_HUMAN [Term] id: CCO:B0011929 name: GFI1B_HUMAN-Phosphoserine261 def: "Protein GFI1B_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:Q5VTD9] xref: UniProtKB:Q5VTD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001898 ! GFI1B_HUMAN [Term] id: CCO:B0011930 name: GGA1_HUMAN-Phosphoserine236 def: "Protein GGA1_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:Q9UJY5] xref: UniProtKB:Q9UJY5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005670 ! GGA1_HUMAN [Term] id: CCO:B0011931 name: GGA1_HUMAN-Phosphoserine355 def: "Protein GGA1_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q9UJY5] comment: by CK2; Probable xref: UniProtKB:Q9UJY5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: transformation_of CCO:B0005670 ! GGA1_HUMAN [Term] id: CCO:B0011932 name: GIT1_HUMAN-Phosphoserine134 def: "Protein GIT1_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011933 name: GIT1_HUMAN-Phosphoserine361 def: "Protein GIT1_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] comment: By similarity xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011934 name: GIT1_HUMAN-Phosphoserine362 def: "Protein GIT1_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011935 name: GIT1_HUMAN-Phosphoserine385 def: "Protein GIT1_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011936 name: GIT1_HUMAN-Phosphoserine388 def: "Protein GIT1_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011937 name: GIT1_HUMAN-Phosphotyrosine545 def: "Protein GIT1_HUMAN with the residue 545 substituted with Phosphotyrosine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011938 name: GIT1_HUMAN-Phosphotyrosine554 def: "Protein GIT1_HUMAN with the residue 554 substituted with Phosphotyrosine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011939 name: GIT1_HUMAN-Phosphoserine592 def: "Protein GIT1_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011940 name: GIT1_HUMAN-Phosphotyrosine598 def: "Protein GIT1_HUMAN with the residue 598 substituted with Phosphotyrosine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0011941 name: GLI3_HUMAN-Phosphoserine19 def: "Protein GLI3_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:P10071] xref: UniProtKB:P10071 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005850 ! GLI3_HUMAN [Term] id: CCO:B0011942 name: GLU2B_HUMAN-Phosphoserine89 def: "Protein GLU2B_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:P14314] comment: by PKC; Potential xref: UniProtKB:P14314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006228 ! GLU2B_HUMAN [Term] id: CCO:B0011943 name: GLU2B_HUMAN-Phosphoserine383 def: "Protein GLU2B_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:P14314] comment: by PKC; Potential xref: UniProtKB:P14314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000943 ! alpha-glucosidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000846 ! alpha-glucosidase II complex relationship: transformation_of CCO:B0006228 ! GLU2B_HUMAN [Term] id: CCO:B0011944 name: GLU2B_HUMAN-Phosphoserine390 def: "Protein GLU2B_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:P14314] comment: by PKC; Potential xref: UniProtKB:P14314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006228 ! GLU2B_HUMAN [Term] id: CCO:B0011945 name: GLU2B_HUMAN-Phosphoserine434 def: "Protein GLU2B_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:P14314] comment: by PKC; Potential xref: UniProtKB:P14314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006228 ! GLU2B_HUMAN [Term] id: CCO:B0011946 name: GLYAT_HUMAN-N6-acetyllysine20 def: "Protein GLYAT_HUMAN with the residue 20 substituted with N6-acetyllysine" [UniProtKB:Q6IB77] comment: By similarity xref: UniProtKB:Q6IB77 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0007260 ! glycine N-acyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0006195 ! GLYAT_HUMAN [Term] id: CCO:B0011947 name: GLYC_HUMAN-Phosphotyrosine34 def: "Protein GLYC_HUMAN with the residue 34 substituted with Phosphotyrosine" [UniProtKB:P34896] comment: By similarity xref: UniProtKB:P34896 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006184 ! GLYC_HUMAN [Term] id: CCO:B0011948 name: GNA13_HUMAN-Phosphothreonine203 def: "Protein GNA13_HUMAN with the residue 203 substituted with Phosphothreonine" [UniProtKB:Q14344] comment: by PKA; xref: UniProtKB:Q14344 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005635 ! GNA13_HUMAN [Term] id: CCO:B0011949 name: GNAI1_HUMAN-ADP-ribosylarginine178 def: "Protein GNAI1_HUMAN with the residue 178 substituted with ADP-ribosylarginine" [UniProtKB:P63096] comment: by cholera toxin; By similarity xref: UniProtKB:P63096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0005493 ! GNAI1_HUMAN [Term] id: CCO:B0011950 name: GNAI1_HUMAN-ADP-ribosylcysteine351 def: "Protein GNAI1_HUMAN with the residue 351 substituted with ADP-ribosylcysteine" [UniProtKB:P63096] comment: by pertussis toxin; By similarity xref: UniProtKB:P63096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005493 ! GNAI1_HUMAN [Term] id: CCO:B0011951 name: GNAI2_HUMAN-ADP-ribosylarginine179 def: "Protein GNAI2_HUMAN with the residue 179 substituted with ADP-ribosylarginine" [UniProtKB:P04899] comment: by cholera toxin; By similarity xref: UniProtKB:P04899 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005754 ! GNAI2_HUMAN [Term] id: CCO:B0011952 name: GNAI2_HUMAN-ADP-ribosylcysteine352 def: "Protein GNAI2_HUMAN with the residue 352 substituted with ADP-ribosylcysteine" [UniProtKB:P04899] comment: by pertussis toxin; By similarity xref: UniProtKB:P04899 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005754 ! GNAI2_HUMAN [Term] id: CCO:B0011953 name: GNDS_HUMAN-Phosphotyrosine586 def: "Protein GNDS_HUMAN with the residue 586 substituted with Phosphotyrosine" [UniProtKB:Q12967] xref: UniProtKB:Q12967 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005912 ! GNDS_HUMAN [Term] id: CCO:B0011954 name: GOGA2_HUMAN-Phosphoserine8 def: "Protein GOGA2_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q08379] xref: UniProtKB:Q08379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006274 ! GOGA2_HUMAN [Term] id: CCO:B0011955 name: GOGA2_HUMAN-Phosphoserine25 def: "Protein GOGA2_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q08379] xref: UniProtKB:Q08379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006274 ! GOGA2_HUMAN [Term] id: CCO:B0011956 name: GOGA2_HUMAN-Phosphoserine111 def: "Protein GOGA2_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:Q08379] comment: By similarity xref: UniProtKB:Q08379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006274 ! GOGA2_HUMAN [Term] id: CCO:B0011957 name: GORS2_HUMAN-Omega-N-methylated arginine30 def: "Protein GORS2_HUMAN with the residue 30 substituted with Omega-N-methylated arginine" [UniProtKB:Q9H8Y8] comment: By similarity xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011958 name: GORS2_HUMAN-Omega-N-methylated arginine47 def: "Protein GORS2_HUMAN with the residue 47 substituted with Omega-N-methylated arginine" [UniProtKB:Q9H8Y8] comment: By similarity xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011959 name: GORS2_HUMAN-Phosphoserine214 def: "Protein GORS2_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011960 name: GORS2_HUMAN-Phosphothreonine222 def: "Protein GORS2_HUMAN with the residue 222 substituted with Phosphothreonine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011961 name: GORS2_HUMAN-Phosphothreonine225 def: "Protein GORS2_HUMAN with the residue 225 substituted with Phosphothreonine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000378 ! Golgi medial cisterna relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011962 name: GORS2_HUMAN-Phosphoserine409 def: "Protein GORS2_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q9H8Y8] comment: By similarity xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011963 name: GORS2_HUMAN-Phosphothreonine415 def: "Protein GORS2_HUMAN with the residue 415 substituted with Phosphothreonine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011964 name: GORS2_HUMAN-Phosphoserine451 def: "Protein GORS2_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0011965 name: GP1BA_HUMAN-Sulfotyrosine292 def: "Protein GP1BA_HUMAN with the residue 292 substituted with Sulfotyrosine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0011966 name: GP1BA_HUMAN-Sulfotyrosine294 def: "Protein GP1BA_HUMAN with the residue 294 substituted with Sulfotyrosine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0011967 name: GP1BA_HUMAN-Sulfotyrosine295 def: "Protein GP1BA_HUMAN with the residue 295 substituted with Sulfotyrosine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0011968 name: GPSM2_HUMAN-Phosphoserine125 def: "Protein GPSM2_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:P81274] comment: by PKG; Potential xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0011969 name: GPSM2_HUMAN-Phosphoserine345 def: "Protein GPSM2_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:P81274] comment: by PKG; Potential xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0011970 name: GPSM2_HUMAN-Phosphoserine401 def: "Protein GPSM2_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:P81274] comment: by PKA; Potential xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0011971 name: GPSM2_HUMAN-Phosphoserine494 def: "Protein GPSM2_HUMAN with the residue 494 substituted with Phosphoserine" [UniProtKB:P81274] comment: by PKC; Potential xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0011972 name: GPSM2_HUMAN-Phosphoserine600 def: "Protein GPSM2_HUMAN with the residue 600 substituted with Phosphoserine" [UniProtKB:P81274] comment: by PKG; Potential xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0011973 name: GRB2_HUMAN-Phosphotyrosine160 def: "Protein GRB2_HUMAN with the residue 160 substituted with Phosphotyrosine" [UniProtKB:P62993] xref: UniProtKB:P62993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001456 ! epidermal growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005875 ! insulin receptor substrate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:B0011974 name: GRB2_HUMAN-Phosphotyrosine209 def: "Protein GRB2_HUMAN with the residue 209 substituted with Phosphotyrosine" [UniProtKB:P62993] xref: UniProtKB:P62993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:B0011975 name: GRLF1_HUMAN-Phosphothreonine685 def: "Protein GRLF1_HUMAN with the residue 685 substituted with Phosphothreonine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0011976 name: GRLF1_HUMAN-Phosphoserine773 def: "Protein GRLF1_HUMAN with the residue 773 substituted with Phosphoserine" [UniProtKB:Q9NRY4] comment: By similarity xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0011977 name: GRLF1_HUMAN-Phosphoserine980 def: "Protein GRLF1_HUMAN with the residue 980 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0011978 name: GRLF1_HUMAN-Phosphotyrosine1105 def: "Protein GRLF1_HUMAN with the residue 1105 substituted with Phosphotyrosine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0011979 name: GRLF1_HUMAN-Phosphoserine1134 def: "Protein GRLF1_HUMAN with the residue 1134 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0011980 name: GRLF1_HUMAN-Phosphoserine1179 def: "Protein GRLF1_HUMAN with the residue 1179 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0011981 name: GRLF1_HUMAN-Phosphoserine1195 def: "Protein GRLF1_HUMAN with the residue 1195 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0011982 name: GRP75_HUMAN-Phosphoserine200 def: "Protein GRP75_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:P38646] xref: UniProtKB:P38646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:B0011983 name: GRP75_HUMAN-N6-acetyllysine288 def: "Protein GRP75_HUMAN with the residue 288 substituted with N6-acetyllysine" [UniProtKB:P38646] comment: By similarity xref: UniProtKB:P38646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:B0011984 name: GRP75_HUMAN-N6-acetyllysine300 def: "Protein GRP75_HUMAN with the residue 300 substituted with N6-acetyllysine" [UniProtKB:P38646] comment: By similarity xref: UniProtKB:P38646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:B0011985 name: GRP78_HUMAN-Phosphothreonine166 def: "Protein GRP78_HUMAN with the residue 166 substituted with Phosphothreonine" [UniProtKB:P11021] comment: By similarity xref: UniProtKB:P11021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:B0011986 name: GRP78_HUMAN-Phosphotyrosine466 def: "Protein GRP78_HUMAN with the residue 466 substituted with Phosphotyrosine" [UniProtKB:P11021] xref: UniProtKB:P11021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:B0011987 name: GRP78_HUMAN-Phosphoserine571 def: "Protein GRP78_HUMAN with the residue 571 substituted with Phosphoserine" [UniProtKB:P11021] comment: By similarity xref: UniProtKB:P11021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:B0011988 name: GRWD1_HUMAN-Phosphoserine119 def: "Protein GRWD1_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q9BQ67] xref: UniProtKB:Q9BQ67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005687 ! GRWD1_HUMAN [Term] id: CCO:B0011989 name: GRWD1_HUMAN-Phosphoserine122 def: "Protein GRWD1_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q9BQ67] xref: UniProtKB:Q9BQ67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005687 ! GRWD1_HUMAN [Term] id: CCO:B0011990 name: GTSE1_HUMAN-Phosphoserine168 def: "Protein GTSE1_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011991 name: GTSE1_HUMAN-Phosphoserine494 def: "Protein GTSE1_HUMAN with the residue 494 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011992 name: GTSE1_HUMAN-Phosphoserine495 def: "Protein GTSE1_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011993 name: GTSE1_HUMAN-Phosphoserine501 def: "Protein GTSE1_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011994 name: GTSE1_HUMAN-Phosphoserine504 def: "Protein GTSE1_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011995 name: GTSE1_HUMAN-Phosphoserine536 def: "Protein GTSE1_HUMAN with the residue 536 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011996 name: GTSE1_HUMAN-Phosphoserine575 def: "Protein GTSE1_HUMAN with the residue 575 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011997 name: GTSE1_HUMAN-Phosphoserine580 def: "Protein GTSE1_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011998 name: GTSE1_HUMAN-Phosphoserine592 def: "Protein GTSE1_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0011999 name: H11_HUMAN-N-acetylserine2 def: "Protein H11_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q02539] comment: By similarity xref: UniProtKB:Q02539 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005863 ! H11_HUMAN [Term] id: CCO:B0012000 name: H11_HUMAN-Phosphothreonine162 def: "Protein H11_HUMAN with the residue 162 substituted with Phosphothreonine" [UniProtKB:Q02539] xref: UniProtKB:Q02539 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005863 ! H11_HUMAN [Term] id: CCO:B0012001 name: H14_HUMAN-N-acetylserine2 def: "Protein H14_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P10412] xref: UniProtKB:P10412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005838 ! H14_HUMAN [Term] id: CCO:B0012002 name: H14_HUMAN-Phosphothreonine4 def: "Protein H14_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:P10412] comment: By similarity xref: UniProtKB:P10412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005838 ! H14_HUMAN [Term] id: CCO:B0012003 name: H14_HUMAN-Phosphothreonine18 def: "Protein H14_HUMAN with the residue 18 substituted with Phosphothreonine" [UniProtKB:P10412] xref: UniProtKB:P10412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005838 ! H14_HUMAN [Term] id: CCO:B0012004 name: H14_HUMAN-N6-methyllysine26 def: "Protein H14_HUMAN with the residue 26 substituted with N6-methyllysine" [UniProtKB:P10412] comment: partial; xref: UniProtKB:P10412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005838 ! H14_HUMAN [Term] id: CCO:B0012005 name: H14_HUMAN-Phosphoserine27 def: "Protein H14_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P10412] xref: UniProtKB:P10412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005838 ! H14_HUMAN [Term] id: CCO:B0012006 name: H14_HUMAN-Phosphoserine36 def: "Protein H14_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P10412] xref: UniProtKB:P10412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005838 ! H14_HUMAN [Term] id: CCO:B0012007 name: H14_HUMAN-Phosphoserine187 def: "Protein H14_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:P10412] xref: UniProtKB:P10412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005838 ! H14_HUMAN [Term] id: CCO:B0012008 name: H2AX_HUMAN-N-acetylserine2 def: "Protein H2AX_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P16104] comment: By similarity xref: UniProtKB:P16104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:B0012009 name: H2AX_HUMAN-Phosphoserine2 def: "Protein H2AX_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P16104] comment: By similarity xref: UniProtKB:P16104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:B0012010 name: H2AX_HUMAN-Phosphoserine140 def: "Protein H2AX_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P16104] comment: by ATM, ATR and PRKDC; xref: UniProtKB:P16104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:B0012011 name: H2B1C_HUMAN-N6-acetyllysine6 def: "Protein H2B1C_HUMAN with the residue 6 substituted with N6-acetyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012012 name: H2B1C_HUMAN-N6-acetyllysine12 def: "Protein H2B1C_HUMAN with the residue 12 substituted with N6-acetyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012013 name: H2B1C_HUMAN-N6-acetyllysine13 def: "Protein H2B1C_HUMAN with the residue 13 substituted with N6-acetyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012014 name: H2B1C_HUMAN-Phosphoserine15 def: "Protein H2B1C_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:P62807] comment: by STK4; xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012015 name: H2B1C_HUMAN-N6-acetyllysine16 def: "Protein H2B1C_HUMAN with the residue 16 substituted with N6-acetyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012016 name: H2B1C_HUMAN-N6-acetyllysine17 def: "Protein H2B1C_HUMAN with the residue 17 substituted with N6-acetyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012017 name: H2B1C_HUMAN-N6-acetyllysine21 def: "Protein H2B1C_HUMAN with the residue 21 substituted with N6-acetyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012018 name: H2B1C_HUMAN-N6-acetyllysine24 def: "Protein H2B1C_HUMAN with the residue 24 substituted with N6-acetyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012019 name: H2B1C_HUMAN-N6-methyllysine47 def: "Protein H2B1C_HUMAN with the residue 47 substituted with N6-methyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012020 name: H2B1C_HUMAN-N6,N6-dimethyllysine58 def: "Protein H2B1C_HUMAN with the residue 58 substituted with N6,N6-dimethyllysine" [UniProtKB:P62807] xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012021 name: H2B1C_HUMAN-N6-acetyllysine109 def: "Protein H2B1C_HUMAN with the residue 109 substituted with N6-acetyllysine" [UniProtKB:P62807] comment: alternate; xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012022 name: H2B1C_HUMAN-N6-methyllysine109 def: "Protein H2B1C_HUMAN with the residue 109 substituted with N6-methyllysine" [UniProtKB:P62807] comment: alternate; xref: UniProtKB:P62807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005771 ! H2B1C_HUMAN [Term] id: CCO:B0012023 name: H31_HUMAN-Phosphothreonine4 def: "Protein H31_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012024 name: H31_HUMAN-N6-acetyllysine5 def: "Protein H31_HUMAN with the residue 5 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012025 name: H31_HUMAN-N6-methyllysine5 def: "Protein H31_HUMAN with the residue 5 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012026 name: H31_HUMAN-Citrulline9 def: "Protein H31_HUMAN with the residue 9 substituted with Citrulline" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012027 name: H31_HUMAN-dimethylarginine9 def: "Protein H31_HUMAN with the residue 9 substituted with dimethylarginine" [UniProtKB:P68431] comment: by PRMT5; alternate; By similarity xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012028 name: H31_HUMAN-N6,N6,N6-trimethyllysine10 def: "Protein H31_HUMAN with the residue 10 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012029 name: H31_HUMAN-N6,N6-dimethyllysine10 def: "Protein H31_HUMAN with the residue 10 substituted with N6,N6-dimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012030 name: H31_HUMAN-N6-acetyllysine10 def: "Protein H31_HUMAN with the residue 10 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012031 name: H31_HUMAN-N6-methyllysine10 def: "Protein H31_HUMAN with the residue 10 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012032 name: H31_HUMAN-Phosphoserine11 def: "Protein H31_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012033 name: H31_HUMAN-Phosphothreonine12 def: "Protein H31_HUMAN with the residue 12 substituted with Phosphothreonine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012034 name: H31_HUMAN-N6-acetyllysine15 def: "Protein H31_HUMAN with the residue 15 substituted with N6-acetyllysine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012035 name: H31_HUMAN-dimethylarginine18 def: "Protein H31_HUMAN with the residue 18 substituted with dimethylarginine" [UniProtKB:P68431] comment: by CARM1; alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012036 name: H31_HUMAN-Citrulline18 def: "Protein H31_HUMAN with the residue 18 substituted with Citrulline" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012037 name: H31_HUMAN-N6-acetyllysine19 def: "Protein H31_HUMAN with the residue 19 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012038 name: H31_HUMAN-N6-methyllysine19 def: "Protein H31_HUMAN with the residue 19 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012039 name: H31_HUMAN-N6-acetyllysine24 def: "Protein H31_HUMAN with the residue 24 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012040 name: H31_HUMAN-N6-methyllysine24 def: "Protein H31_HUMAN with the residue 24 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012041 name: H31_HUMAN-N6,N6,N6-trimethyllysine28 def: "Protein H31_HUMAN with the residue 28 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012042 name: H31_HUMAN-N6,N6-dimethyllysine28 def: "Protein H31_HUMAN with the residue 28 substituted with N6,N6-dimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012043 name: H31_HUMAN-N6-acetyllysine28 def: "Protein H31_HUMAN with the residue 28 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012044 name: H31_HUMAN-N6-methyllysine28 def: "Protein H31_HUMAN with the residue 28 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012045 name: H31_HUMAN-Phosphoserine29 def: "Protein H31_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012046 name: H31_HUMAN-N6,N6,N6-trimethyllysine37 def: "Protein H31_HUMAN with the residue 37 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012047 name: H31_HUMAN-N6,N6-dimethyllysine37 def: "Protein H31_HUMAN with the residue 37 substituted with N6,N6-dimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012048 name: H31_HUMAN-N6-acetyllysine37 def: "Protein H31_HUMAN with the residue 37 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012049 name: H31_HUMAN-N6-methyllysine37 def: "Protein H31_HUMAN with the residue 37 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012050 name: H31_HUMAN-N6-methyllysine38 def: "Protein H31_HUMAN with the residue 38 substituted with N6-methyllysine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012051 name: H31_HUMAN-N6,N6,N6-trimethyllysine57 def: "Protein H31_HUMAN with the residue 57 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012052 name: H31_HUMAN-N6-acetyllysine57 def: "Protein H31_HUMAN with the residue 57 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012053 name: H31_HUMAN-N6-methyllysine57 def: "Protein H31_HUMAN with the residue 57 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012054 name: H31_HUMAN-N6-methyllysine65 def: "Protein H31_HUMAN with the residue 65 substituted with N6-methyllysine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012055 name: H31_HUMAN-N6,N6,N6-trimethyllysine80 def: "Protein H31_HUMAN with the residue 80 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P68431] comment: alternate; By similarity xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012056 name: H31_HUMAN-N6,N6-dimethyllysine80 def: "Protein H31_HUMAN with the residue 80 substituted with N6,N6-dimethyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012057 name: H31_HUMAN-N6-acetyllysine80 def: "Protein H31_HUMAN with the residue 80 substituted with N6-acetyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012058 name: H31_HUMAN-N6-methyllysine80 def: "Protein H31_HUMAN with the residue 80 substituted with N6-methyllysine" [UniProtKB:P68431] comment: alternate; xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012059 name: H31_HUMAN-N6-methyllysine123 def: "Protein H31_HUMAN with the residue 123 substituted with N6-methyllysine" [UniProtKB:P68431] xref: UniProtKB:P68431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005221 ! H31_HUMAN [Term] id: CCO:B0012060 name: H32_HUMAN-Phosphothreonine4 def: "Protein H32_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012061 name: H32_HUMAN-N6-acetyllysine5 def: "Protein H32_HUMAN with the residue 5 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012062 name: H32_HUMAN-N6-methyllysine5 def: "Protein H32_HUMAN with the residue 5 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012063 name: H32_HUMAN-Citrulline9 def: "Protein H32_HUMAN with the residue 9 substituted with Citrulline" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012064 name: H32_HUMAN-dimethylarginine9 def: "Protein H32_HUMAN with the residue 9 substituted with dimethylarginine" [UniProtKB:Q71DI3] comment: by PRMT5; alternate; By similarity xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012065 name: H32_HUMAN-N6,N6,N6-trimethyllysine10 def: "Protein H32_HUMAN with the residue 10 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012066 name: H32_HUMAN-N6,N6-dimethyllysine10 def: "Protein H32_HUMAN with the residue 10 substituted with N6,N6-dimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012067 name: H32_HUMAN-N6-acetyllysine10 def: "Protein H32_HUMAN with the residue 10 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012068 name: H32_HUMAN-N6-methyllysine10 def: "Protein H32_HUMAN with the residue 10 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012069 name: H32_HUMAN-Phosphoserine11 def: "Protein H32_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012070 name: H32_HUMAN-Phosphothreonine12 def: "Protein H32_HUMAN with the residue 12 substituted with Phosphothreonine" [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012071 name: H32_HUMAN-N6-acetyllysine15 def: "Protein H32_HUMAN with the residue 15 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012072 name: H32_HUMAN-dimethylarginine18 def: "Protein H32_HUMAN with the residue 18 substituted with dimethylarginine" [UniProtKB:Q71DI3] comment: by CARM1; alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012073 name: H32_HUMAN-Citrulline18 def: "Protein H32_HUMAN with the residue 18 substituted with Citrulline" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012074 name: H32_HUMAN-N6-acetyllysine19 def: "Protein H32_HUMAN with the residue 19 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012075 name: H32_HUMAN-N6-methyllysine19 def: "Protein H32_HUMAN with the residue 19 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012076 name: H32_HUMAN-N6-acetyllysine24 def: "Protein H32_HUMAN with the residue 24 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012077 name: H32_HUMAN-N6-methyllysine24 def: "Protein H32_HUMAN with the residue 24 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012078 name: H32_HUMAN-N6,N6,N6-trimethyllysine28 def: "Protein H32_HUMAN with the residue 28 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012079 name: H32_HUMAN-N6,N6-dimethyllysine28 def: "Protein H32_HUMAN with the residue 28 substituted with N6,N6-dimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012080 name: H32_HUMAN-N6-acetyllysine28 def: "Protein H32_HUMAN with the residue 28 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012081 name: H32_HUMAN-N6-methyllysine28 def: "Protein H32_HUMAN with the residue 28 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012082 name: H32_HUMAN-Phosphoserine29 def: "Protein H32_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012083 name: H32_HUMAN-N6,N6,N6-trimethyllysine37 def: "Protein H32_HUMAN with the residue 37 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012084 name: H32_HUMAN-N6,N6-dimethyllysine37 def: "Protein H32_HUMAN with the residue 37 substituted with N6,N6-dimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012085 name: H32_HUMAN-N6-acetyllysine37 def: "Protein H32_HUMAN with the residue 37 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012086 name: H32_HUMAN-N6-methyllysine37 def: "Protein H32_HUMAN with the residue 37 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012087 name: H32_HUMAN-N6,N6,N6-trimethyllysine57 def: "Protein H32_HUMAN with the residue 57 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012088 name: H32_HUMAN-N6-acetyllysine57 def: "Protein H32_HUMAN with the residue 57 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012089 name: H32_HUMAN-N6-methyllysine57 def: "Protein H32_HUMAN with the residue 57 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012090 name: H32_HUMAN-N6-methyllysine65 def: "Protein H32_HUMAN with the residue 65 substituted with N6-methyllysine" [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012091 name: H32_HUMAN-N6,N6,N6-trimethyllysine80 def: "Protein H32_HUMAN with the residue 80 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:Q71DI3] comment: alternate; By similarity xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012092 name: H32_HUMAN-N6,N6-dimethyllysine80 def: "Protein H32_HUMAN with the residue 80 substituted with N6,N6-dimethyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012093 name: H32_HUMAN-N6-acetyllysine80 def: "Protein H32_HUMAN with the residue 80 substituted with N6-acetyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012094 name: H32_HUMAN-N6-methyllysine80 def: "Protein H32_HUMAN with the residue 80 substituted with N6-methyllysine" [UniProtKB:Q71DI3] comment: alternate; xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012095 name: H32_HUMAN-N6-methyllysine123 def: "Protein H32_HUMAN with the residue 123 substituted with N6-methyllysine" [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005285 ! H32_HUMAN [Term] id: CCO:B0012096 name: H33_HUMAN-Phosphothreonine4 def: "Protein H33_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012097 name: H33_HUMAN-N6-acetyllysine5 def: "Protein H33_HUMAN with the residue 5 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012098 name: H33_HUMAN-N6-methyllysine5 def: "Protein H33_HUMAN with the residue 5 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012099 name: H33_HUMAN-Citrulline9 def: "Protein H33_HUMAN with the residue 9 substituted with Citrulline" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012100 name: H33_HUMAN-dimethylarginine9 def: "Protein H33_HUMAN with the residue 9 substituted with dimethylarginine" [UniProtKB:P84243] comment: by PRMT5; alternate; By similarity xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012101 name: H33_HUMAN-N6,N6,N6-trimethyllysine10 def: "Protein H33_HUMAN with the residue 10 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012102 name: H33_HUMAN-N6,N6-dimethyllysine10 def: "Protein H33_HUMAN with the residue 10 substituted with N6,N6-dimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012103 name: H33_HUMAN-N6-acetyllysine10 def: "Protein H33_HUMAN with the residue 10 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012104 name: H33_HUMAN-N6-methyllysine10 def: "Protein H33_HUMAN with the residue 10 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012105 name: H33_HUMAN-Phosphoserine11 def: "Protein H33_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012106 name: H33_HUMAN-Phosphothreonine12 def: "Protein H33_HUMAN with the residue 12 substituted with Phosphothreonine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012107 name: H33_HUMAN-N6-acetyllysine15 def: "Protein H33_HUMAN with the residue 15 substituted with N6-acetyllysine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012108 name: H33_HUMAN-dimethylarginine18 def: "Protein H33_HUMAN with the residue 18 substituted with dimethylarginine" [UniProtKB:P84243] comment: by CARM1; alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012109 name: H33_HUMAN-Citrulline18 def: "Protein H33_HUMAN with the residue 18 substituted with Citrulline" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012110 name: H33_HUMAN-N6-acetyllysine19 def: "Protein H33_HUMAN with the residue 19 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012111 name: H33_HUMAN-N6-methyllysine19 def: "Protein H33_HUMAN with the residue 19 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012112 name: H33_HUMAN-N6-acetyllysine24 def: "Protein H33_HUMAN with the residue 24 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012113 name: H33_HUMAN-N6-methyllysine24 def: "Protein H33_HUMAN with the residue 24 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012114 name: H33_HUMAN-N6,N6,N6-trimethyllysine28 def: "Protein H33_HUMAN with the residue 28 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012115 name: H33_HUMAN-N6,N6-dimethyllysine28 def: "Protein H33_HUMAN with the residue 28 substituted with N6,N6-dimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012116 name: H33_HUMAN-N6-acetyllysine28 def: "Protein H33_HUMAN with the residue 28 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012117 name: H33_HUMAN-N6-methyllysine28 def: "Protein H33_HUMAN with the residue 28 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000183 ! Barr body relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012118 name: H33_HUMAN-Phosphoserine29 def: "Protein H33_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012119 name: H33_HUMAN-Phosphoserine32 def: "Protein H33_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012120 name: H33_HUMAN-N6,N6,N6-trimethyllysine37 def: "Protein H33_HUMAN with the residue 37 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012121 name: H33_HUMAN-N6,N6-dimethyllysine37 def: "Protein H33_HUMAN with the residue 37 substituted with N6,N6-dimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012122 name: H33_HUMAN-N6-acetyllysine37 def: "Protein H33_HUMAN with the residue 37 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012123 name: H33_HUMAN-N6-methyllysine37 def: "Protein H33_HUMAN with the residue 37 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012124 name: H33_HUMAN-N6,N6,N6-trimethyllysine57 def: "Protein H33_HUMAN with the residue 57 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012125 name: H33_HUMAN-N6-acetyllysine57 def: "Protein H33_HUMAN with the residue 57 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012126 name: H33_HUMAN-N6-methyllysine57 def: "Protein H33_HUMAN with the residue 57 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012127 name: H33_HUMAN-N6-methyllysine65 def: "Protein H33_HUMAN with the residue 65 substituted with N6-methyllysine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012128 name: H33_HUMAN-N6,N6,N6-trimethyllysine80 def: "Protein H33_HUMAN with the residue 80 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P84243] comment: alternate; Probable xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012129 name: H33_HUMAN-N6,N6-dimethyllysine80 def: "Protein H33_HUMAN with the residue 80 substituted with N6,N6-dimethyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012130 name: H33_HUMAN-N6-acetyllysine80 def: "Protein H33_HUMAN with the residue 80 substituted with N6-acetyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012131 name: H33_HUMAN-N6-methyllysine80 def: "Protein H33_HUMAN with the residue 80 substituted with N6-methyllysine" [UniProtKB:P84243] comment: alternate; xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012132 name: H33_HUMAN-N6-methyllysine123 def: "Protein H33_HUMAN with the residue 123 substituted with N6-methyllysine" [UniProtKB:P84243] xref: UniProtKB:P84243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005927 ! H33_HUMAN [Term] id: CCO:B0012133 name: H4_HUMAN-N-acetylserine2 def: "Protein H4_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012134 name: H4_HUMAN-dimethylarginine4 def: "Protein H4_HUMAN with the residue 4 substituted with dimethylarginine" [UniProtKB:P62805] comment: by PRMT5; alternate; By similarity xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012135 name: H4_HUMAN-N6-acetyllysine6 def: "Protein H4_HUMAN with the residue 6 substituted with N6-acetyllysine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012136 name: H4_HUMAN-N6-acetyllysine9 def: "Protein H4_HUMAN with the residue 9 substituted with N6-acetyllysine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012137 name: H4_HUMAN-N6-acetyllysine13 def: "Protein H4_HUMAN with the residue 13 substituted with N6-acetyllysine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012138 name: H4_HUMAN-N6-acetyllysine17 def: "Protein H4_HUMAN with the residue 17 substituted with N6-acetyllysine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012139 name: H4_HUMAN-N6,N6-dimethyllysine21 def: "Protein H4_HUMAN with the residue 21 substituted with N6,N6-dimethyllysine" [UniProtKB:P62805] comment: alternate; xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012140 name: H4_HUMAN-N6-methyllysine21 def: "Protein H4_HUMAN with the residue 21 substituted with N6-methyllysine" [UniProtKB:P62805] comment: alternate; xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012141 name: H4_HUMAN-Phosphoserine48 def: "Protein H4_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0012142 name: HASP_HUMAN-Phosphoserine220 def: "Protein HASP_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q8TF76] xref: UniProtKB:Q8TF76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001999 ! HASP_HUMAN [Term] id: CCO:B0012143 name: HASP_HUMAN-Phosphothreonine253 def: "Protein HASP_HUMAN with the residue 253 substituted with Phosphothreonine" [UniProtKB:Q8TF76] xref: UniProtKB:Q8TF76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001999 ! HASP_HUMAN [Term] id: CCO:B0012144 name: HCFC1_HUMAN-Phosphoserine598 def: "Protein HCFC1_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012145 name: HCFC1_HUMAN-Phosphoserine666 def: "Protein HCFC1_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012146 name: HCFC1_HUMAN-Phosphothreonine733 def: "Protein HCFC1_HUMAN with the residue 733 substituted with Phosphothreonine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012147 name: HCFC1_HUMAN-Phosphothreonine737 def: "Protein HCFC1_HUMAN with the residue 737 substituted with Phosphothreonine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012148 name: HCFC1_HUMAN-Phosphothreonine738 def: "Protein HCFC1_HUMAN with the residue 738 substituted with Phosphothreonine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012149 name: HCFC1_HUMAN-Phosphothreonine1491 def: "Protein HCFC1_HUMAN with the residue 1491 substituted with Phosphothreonine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012150 name: HCFC1_HUMAN-Phosphoserine1507 def: "Protein HCFC1_HUMAN with the residue 1507 substituted with Phosphoserine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012151 name: HCFC1_HUMAN-Phosphoserine2007 def: "Protein HCFC1_HUMAN with the residue 2007 substituted with Phosphoserine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012152 name: HCFC1_HUMAN-Phosphoserine2008 def: "Protein HCFC1_HUMAN with the residue 2008 substituted with Phosphoserine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012153 name: HCFC1_HUMAN-Phosphoserine2020 def: "Protein HCFC1_HUMAN with the residue 2020 substituted with Phosphoserine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0012154 name: HCK_HUMAN-Phosphotyrosine411 def: "Protein HCK_HUMAN with the residue 411 substituted with Phosphotyrosine" [UniProtKB:P08631] comment: by autocatalysis; By similarity xref: UniProtKB:P08631 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:B0012155 name: HDAC1_HUMAN-Phosphotyrosine221 def: "Protein HDAC1_HUMAN with the residue 221 substituted with Phosphotyrosine" [UniProtKB:Q13547] xref: UniProtKB:Q13547 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:B0012156 name: HDAC1_HUMAN-Phosphoserine393 def: "Protein HDAC1_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:Q13547] xref: UniProtKB:Q13547 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:B0012157 name: HDAC1_HUMAN-Phosphoserine421 def: "Protein HDAC1_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q13547] comment: by CK2; xref: UniProtKB:Q13547 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:B0012158 name: HDAC1_HUMAN-Phosphoserine423 def: "Protein HDAC1_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:Q13547] comment: by CK2; xref: UniProtKB:Q13547 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:B0012159 name: HDAC2_HUMAN-Phosphoserine394 def: "Protein HDAC2_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q92769] xref: UniProtKB:Q92769 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000119 ! heterochromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000265 ! replication fork relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:B0012160 name: HDAC2_HUMAN-Phosphoserine407 def: "Protein HDAC2_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q92769] xref: UniProtKB:Q92769 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:B0012161 name: HDAC2_HUMAN-Phosphoserine422 def: "Protein HDAC2_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q92769] xref: UniProtKB:Q92769 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:B0012162 name: HDAC2_HUMAN-Phosphoserine424 def: "Protein HDAC2_HUMAN with the residue 424 substituted with Phosphoserine" [UniProtKB:Q92769] xref: UniProtKB:Q92769 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:B0012163 name: HDAC4_HUMAN-Phosphoserine246 def: "Protein HDAC4_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:P56524] comment: by CaMK4; xref: UniProtKB:P56524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001679 ! HDAC4_HUMAN [Term] id: CCO:B0012164 name: HDAC4_HUMAN-Phosphoserine467 def: "Protein HDAC4_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:P56524] comment: by CaMK4; xref: UniProtKB:P56524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001679 ! HDAC4_HUMAN [Term] id: CCO:B0012165 name: HDAC4_HUMAN-Phosphoserine632 def: "Protein HDAC4_HUMAN with the residue 632 substituted with Phosphoserine" [UniProtKB:P56524] comment: by CaMK4; xref: UniProtKB:P56524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001679 ! HDAC4_HUMAN [Term] id: CCO:B0012166 name: HDAC5_HUMAN-Phosphoserine259 def: "Protein HDAC5_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:Q9UQL6] comment: by CaMK; xref: UniProtKB:Q9UQL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002244 ! HDAC5_HUMAN [Term] id: CCO:B0012167 name: HDAC5_HUMAN-Phosphoserine498 def: "Protein HDAC5_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:Q9UQL6] comment: by CaMK; xref: UniProtKB:Q9UQL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002244 ! HDAC5_HUMAN [Term] id: CCO:B0012168 name: HDAC6_HUMAN-Phosphoserine22 def: "Protein HDAC6_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:Q9UBN7] xref: UniProtKB:Q9UBN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_function CCO:F0005738 ! tubulin deacetylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0002192 ! HDAC6_HUMAN [Term] id: CCO:B0012169 name: HDAC6_HUMAN-Phosphothreonine30 def: "Protein HDAC6_HUMAN with the residue 30 substituted with Phosphothreonine" [UniProtKB:Q9UBN7] xref: UniProtKB:Q9UBN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002192 ! HDAC6_HUMAN [Term] id: CCO:B0012170 name: HDAC7_HUMAN-Phosphoserine358 def: "Protein HDAC7_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:Q8WUI4] comment: By similarity xref: UniProtKB:Q8WUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002002 ! HDAC7_HUMAN [Term] id: CCO:B0012171 name: HDAC7_HUMAN-Phosphoserine487 def: "Protein HDAC7_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:Q8WUI4] xref: UniProtKB:Q8WUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002002 ! HDAC7_HUMAN [Term] id: CCO:B0012172 name: HDAC9_HUMAN-Phosphoserine220 def: "Protein HDAC9_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q9UKV0] comment: By similarity xref: UniProtKB:Q9UKV0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002222 ! HDAC9_HUMAN [Term] id: CCO:B0012173 name: HDAC9_HUMAN-Phosphoserine240 def: "Protein HDAC9_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q9UKV0] comment: By similarity xref: UniProtKB:Q9UKV0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002222 ! HDAC9_HUMAN [Term] id: CCO:B0012174 name: HDAC9_HUMAN-Phosphoserine451 def: "Protein HDAC9_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:Q9UKV0] comment: By similarity xref: UniProtKB:Q9UKV0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002222 ! HDAC9_HUMAN [Term] id: CCO:B0012175 name: HD_HUMAN-Phosphoserine421 def: "Protein HD_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:P42858] xref: UniProtKB:P42858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001514 ! calcium channel regulator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0005407 ! HD_HUMAN [Term] id: CCO:B0012176 name: HD_HUMAN-Phosphoserine1876 def: "Protein HD_HUMAN with the residue 1876 substituted with Phosphoserine" [UniProtKB:P42858] xref: UniProtKB:P42858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005407 ! HD_HUMAN [Term] id: CCO:B0012177 name: HECAM_HUMAN-Phosphoserine278 def: "Protein HECAM_HUMAN with the residue 278 substituted with Phosphoserine" [UniProtKB:Q14CZ8] comment: By similarity xref: UniProtKB:Q14CZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001796 ! HECAM_HUMAN [Term] id: CCO:B0012178 name: HECAM_HUMAN-Phosphoserine318 def: "Protein HECAM_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q14CZ8] comment: By similarity xref: UniProtKB:Q14CZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001796 ! HECAM_HUMAN [Term] id: CCO:B0012179 name: HECAM_HUMAN-Phosphoserine350 def: "Protein HECAM_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:Q14CZ8] comment: By similarity xref: UniProtKB:Q14CZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001796 ! HECAM_HUMAN [Term] id: CCO:B0012180 name: HEXI1_HUMAN-Phosphoserine97 def: "Protein HEXI1_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:O94992] xref: UniProtKB:O94992 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003544 ! snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001445 ! HEXI1_HUMAN [Term] id: CCO:B0012181 name: HEXI1_HUMAN-Phosphoserine98 def: "Protein HEXI1_HUMAN with the residue 98 substituted with Phosphoserine" [UniProtKB:O94992] xref: UniProtKB:O94992 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001445 ! HEXI1_HUMAN [Term] id: CCO:B0012182 name: HEXI2_HUMAN-Phosphoserine51 def: "Protein HEXI2_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q96MH2] xref: UniProtKB:Q96MH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002049 ! HEXI2_HUMAN [Term] id: CCO:B0012183 name: HEXI2_HUMAN-Phosphoserine53 def: "Protein HEXI2_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q96MH2] xref: UniProtKB:Q96MH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002049 ! HEXI2_HUMAN [Term] id: CCO:B0012184 name: HGF_HUMAN-Pyrrolidone carboxylic acid32 def: "Protein HGF_HUMAN with the residue 32 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P14210] xref: UniProtKB:P14210 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: transformation_of CCO:B0001518 ! HGF_HUMAN [Term] id: CCO:B0012185 name: HGS_HUMAN-Phosphotyrosine216 def: "Protein HGS_HUMAN with the residue 216 substituted with Phosphotyrosine" [UniProtKB:O14964] xref: UniProtKB:O14964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:B0012186 name: HGS_HUMAN-Phosphotyrosine308 def: "Protein HGS_HUMAN with the residue 308 substituted with Phosphotyrosine" [UniProtKB:O14964] xref: UniProtKB:O14964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: transformation_of CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:B0012187 name: HGS_HUMAN-Phosphotyrosine329 def: "Protein HGS_HUMAN with the residue 329 substituted with Phosphotyrosine" [UniProtKB:O14964] comment: By similarity xref: UniProtKB:O14964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:B0012188 name: HGS_HUMAN-Phosphotyrosine334 def: "Protein HGS_HUMAN with the residue 334 substituted with Phosphotyrosine" [UniProtKB:O14964] comment: By similarity xref: UniProtKB:O14964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:B0012189 name: HIC1_HUMAN-Phosphoserine313 def: "Protein HIC1_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q14526] comment: By similarity xref: UniProtKB:Q14526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001783 ! HIC1_HUMAN [Term] id: CCO:B0012190 name: HIC1_HUMAN-N6-acetyllysine333 def: "Protein HIC1_HUMAN with the residue 333 substituted with N6-acetyllysine" [UniProtKB:Q14526] comment: alternate; xref: UniProtKB:Q14526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001783 ! HIC1_HUMAN [Term] id: CCO:B0012191 name: HIF1A_HUMAN-4-hydroxyproline402 def: "Protein HIF1A_HUMAN with the residue 402 substituted with 4-hydroxyproline" [UniProtKB:Q16665] xref: UniProtKB:Q16665 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:B0012193 name: HIF1A_HUMAN-4-hydroxyproline564 def: "Protein HIF1A_HUMAN with the residue 564 substituted with 4-hydroxyproline" [UniProtKB:Q16665] xref: UniProtKB:Q16665 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:B0012194 name: HIF1A_HUMAN-S-nitrosocysteine800 def: "Protein HIF1A_HUMAN with the residue 800 substituted with S-nitrosocysteine" [UniProtKB:Q16665] comment: Probable xref: UniProtKB:Q16665 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:B0012195 name: HIF1A_HUMAN-3-hydroxyasparagine803 def: "Protein HIF1A_HUMAN with the residue 803 substituted with 3-hydroxyasparagine" [UniProtKB:Q16665] xref: UniProtKB:Q16665 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005559 ! histone acetyltransferase binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008202 ! Hsp90 protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:B0012196 name: HIPK1_HUMAN-Phosphotyrosine352 def: "Protein HIPK1_HUMAN with the residue 352 substituted with Phosphotyrosine" [UniProtKB:Q86Z02] xref: UniProtKB:Q86Z02 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005675 ! HIPK1_HUMAN [Term] id: CCO:B0012197 name: HMGB1_HUMAN-N6-acetyllysine30 def: "Protein HMGB1_HUMAN with the residue 30 substituted with N6-acetyllysine" [UniProtKB:P09429] xref: UniProtKB:P09429 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005929 ! HMGB1_HUMAN [Term] id: CCO:B0012198 name: HMGB1_HUMAN-Phosphoserine35 def: "Protein HMGB1_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:P09429] xref: UniProtKB:P09429 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005929 ! HMGB1_HUMAN [Term] id: CCO:B0012199 name: HNF1A_HUMAN-Phosphothreonine74 def: "Protein HNF1A_HUMAN with the residue 74 substituted with Phosphothreonine" [UniProtKB:P20823] comment: By similarity xref: UniProtKB:P20823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0006008 ! HNF1A_HUMAN [Term] id: CCO:B0012200 name: HNRH1_HUMAN-N-acetylmethionine2 def: "Protein HNRH1_HUMAN with the residue 2 substituted with N-acetylmethionine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012201 name: HNRH1_HUMAN-Phosphoserine23 def: "Protein HNRH1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012202 name: HNRH1_HUMAN-Phosphoserine63 def: "Protein HNRH1_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012203 name: HNRH1_HUMAN-Phosphothreonine100 def: "Protein HNRH1_HUMAN with the residue 100 substituted with Phosphothreonine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012204 name: HNRH1_HUMAN-Phosphoserine104 def: "Protein HNRH1_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012205 name: HNRH1_HUMAN-Asymmetric dimethylarginine217 def: "Protein HNRH1_HUMAN with the residue 217 substituted with Asymmetric dimethylarginine" [UniProtKB:P31943] comment: By similarity xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012206 name: HNRH1_HUMAN-Phosphotyrosine246 def: "Protein HNRH1_HUMAN with the residue 246 substituted with Phosphotyrosine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012207 name: HNRH1_HUMAN-Phosphotyrosine306 def: "Protein HNRH1_HUMAN with the residue 306 substituted with Phosphotyrosine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012208 name: HNRH1_HUMAN-Phosphoserine310 def: "Protein HNRH1_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0012209 name: HNRH3_HUMAN-Asymmetric dimethylarginine121 def: "Protein HNRH3_HUMAN with the residue 121 substituted with Asymmetric dimethylarginine" [UniProtKB:P31942] xref: UniProtKB:P31942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0006277 ! HNRH3_HUMAN [Term] id: CCO:B0012210 name: HNRH3_HUMAN-Phosphoserine216 def: "Protein HNRH3_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:P31942] xref: UniProtKB:P31942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006277 ! HNRH3_HUMAN [Term] id: CCO:B0012211 name: HNRH3_HUMAN-Phosphotyrosine296 def: "Protein HNRH3_HUMAN with the residue 296 substituted with Phosphotyrosine" [UniProtKB:P31942] xref: UniProtKB:P31942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006277 ! HNRH3_HUMAN [Term] id: CCO:B0012212 name: HNRPC_HUMAN-Phosphoserine138 def: "Protein HNRPC_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012213 name: HNRPC_HUMAN-Phosphoserine162 def: "Protein HNRPC_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012214 name: HNRPC_HUMAN-Phosphoserine233 def: "Protein HNRPC_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012215 name: HNRPC_HUMAN-Phosphoserine238 def: "Protein HNRPC_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012216 name: HNRPC_HUMAN-Phosphoserine239 def: "Protein HNRPC_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012217 name: HNRPC_HUMAN-Phosphoserine240 def: "Protein HNRPC_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012218 name: HNRPC_HUMAN-Phosphoserine241 def: "Protein HNRPC_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012219 name: HNRPC_HUMAN-Phosphoserine253 def: "Protein HNRPC_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012220 name: HNRPC_HUMAN-Phosphoserine260 def: "Protein HNRPC_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012221 name: HNRPC_HUMAN-Phosphoserine299 def: "Protein HNRPC_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0012222 name: HNRPD_HUMAN-Phosphoserine80 def: "Protein HNRPD_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012223 name: HNRPD_HUMAN-Phosphoserine82 def: "Protein HNRPD_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012224 name: HNRPD_HUMAN-Phosphoserine83 def: "Protein HNRPD_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012225 name: HNRPD_HUMAN-Phosphoserine87 def: "Protein HNRPD_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012226 name: HNRPD_HUMAN-Phosphothreonine91 def: "Protein HNRPD_HUMAN with the residue 91 substituted with Phosphothreonine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012227 name: HNRPD_HUMAN-Phosphoserine190 def: "Protein HNRPD_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012228 name: HNRPD_HUMAN-Phosphothreonine193 def: "Protein HNRPD_HUMAN with the residue 193 substituted with Phosphothreonine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012229 name: HNRPD_HUMAN-Omega-N-methylated arginine345 def: "Protein HNRPD_HUMAN with the residue 345 substituted with Omega-N-methylated arginine" [UniProtKB:Q14103] xref: UniProtKB:Q14103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:B0012230 name: HNRPF_HUMAN-N-acetylmethionine2 def: "Protein HNRPF_HUMAN with the residue 2 substituted with N-acetylmethionine" [UniProtKB:P52597] xref: UniProtKB:P52597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005814 ! HNRPF_HUMAN [Term] id: CCO:B0012231 name: HNRPF_HUMAN-Phosphoserine161 def: "Protein HNRPF_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:P52597] xref: UniProtKB:P52597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0005814 ! HNRPF_HUMAN [Term] id: CCO:B0012232 name: HNRPF_HUMAN-Phosphotyrosine246 def: "Protein HNRPF_HUMAN with the residue 246 substituted with Phosphotyrosine" [UniProtKB:P52597] xref: UniProtKB:P52597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005814 ! HNRPF_HUMAN [Term] id: CCO:B0012233 name: HNRPF_HUMAN-Phosphoserine310 def: "Protein HNRPF_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:P52597] xref: UniProtKB:P52597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005814 ! HNRPF_HUMAN [Term] id: CCO:B0012234 name: HNRPG_HUMAN-N-acetylmethionine1 def: "Protein HNRPG_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P38159] comment: alternate; xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012235 name: HNRPG_HUMAN-N-acetylvaline2 def: "Protein HNRPG_HUMAN with the residue 2 substituted with N-acetylvaline" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012236 name: HNRPG_HUMAN-Phosphoserine58 def: "Protein HNRPG_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012237 name: HNRPG_HUMAN-Phosphoserine88 def: "Protein HNRPG_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012238 name: HNRPG_HUMAN-Phosphoserine165 def: "Protein HNRPG_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:P38159] comment: By similarity xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012239 name: HNRPG_HUMAN-Omega-N-methylated arginine185 def: "Protein HNRPG_HUMAN with the residue 185 substituted with Omega-N-methylated arginine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012240 name: HNRPG_HUMAN-Phosphoserine208 def: "Protein HNRPG_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012241 name: HNRPG_HUMAN-Phosphoserine330 def: "Protein HNRPG_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012242 name: HNRPG_HUMAN-Phosphoserine332 def: "Protein HNRPG_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012243 name: HNRPG_HUMAN-Phosphoserine352 def: "Protein HNRPG_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0012244 name: HNRPK_HUMAN-Phosphothreonine3 def: "Protein HNRPK_HUMAN with the residue 3 substituted with Phosphothreonine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012245 name: HNRPK_HUMAN-Phosphoserine36 def: "Protein HNRPK_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012246 name: HNRPK_HUMAN-Phosphoserine116 def: "Protein HNRPK_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012247 name: HNRPK_HUMAN-Phosphoserine214 def: "Protein HNRPK_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012248 name: HNRPK_HUMAN-Phosphoserine216 def: "Protein HNRPK_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012249 name: HNRPK_HUMAN-Phosphoserine284 def: "Protein HNRPK_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012250 name: HNRPK_HUMAN-Omega-N-methylated arginine296 def: "Protein HNRPK_HUMAN with the residue 296 substituted with Omega-N-methylated arginine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012251 name: HNRPK_HUMAN-Omega-N-methylated arginine299 def: "Protein HNRPK_HUMAN with the residue 299 substituted with Omega-N-methylated arginine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012252 name: HNRPK_HUMAN-Phosphoserine379 def: "Protein HNRPK_HUMAN with the residue 379 substituted with Phosphoserine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0012253 name: HOOK1_HUMAN-Phosphoserine235 def: "Protein HOOK1_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q9UJC3] xref: UniProtKB:Q9UJC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0005594 ! HOOK1_HUMAN [Term] id: CCO:B0012254 name: HOOK1_HUMAN-Phosphothreonine699 def: "Protein HOOK1_HUMAN with the residue 699 substituted with Phosphothreonine" [UniProtKB:Q9UJC3] xref: UniProtKB:Q9UJC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005594 ! HOOK1_HUMAN [Term] id: CCO:B0012255 name: HRX_HUMAN-Phosphoserine279 def: "Protein HRX_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012256 name: HRX_HUMAN-Phosphothreonine337 def: "Protein HRX_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012257 name: HRX_HUMAN-Phosphoserine1837 def: "Protein HRX_HUMAN with the residue 1837 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012258 name: HRX_HUMAN-Phosphoserine2151 def: "Protein HRX_HUMAN with the residue 2151 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012259 name: HRX_HUMAN-Phosphoserine2866 def: "Protein HRX_HUMAN with the residue 2866 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012260 name: HRX_HUMAN-Phosphothreonine2940 def: "Protein HRX_HUMAN with the residue 2940 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012261 name: HRX_HUMAN-Phosphoserine3036 def: "Protein HRX_HUMAN with the residue 3036 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012262 name: HRX_HUMAN-Phosphoserine3511 def: "Protein HRX_HUMAN with the residue 3511 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0012263 name: HS90A_HUMAN-Phosphothreonine5 def: "Protein HS90A_HUMAN with the residue 5 substituted with Phosphothreonine" [UniProtKB:P07900] comment: by PRKDC; xref: UniProtKB:P07900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:B0012264 name: HS90A_HUMAN-Phosphothreonine7 def: "Protein HS90A_HUMAN with the residue 7 substituted with Phosphothreonine" [UniProtKB:P07900] comment: by PRKDC; xref: UniProtKB:P07900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:B0012265 name: HS90A_HUMAN-Phosphoserine231 def: "Protein HS90A_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:P07900] xref: UniProtKB:P07900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:B0012266 name: HS90A_HUMAN-Phosphoserine252 def: "Protein HS90A_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:P07900] xref: UniProtKB:P07900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:B0012267 name: HS90A_HUMAN-Phosphoserine263 def: "Protein HS90A_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:P07900] xref: UniProtKB:P07900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:B0012268 name: HS90B_HUMAN-Phosphoserine226 def: "Protein HS90B_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:P08238] xref: UniProtKB:P08238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:B0012269 name: HS90B_HUMAN-Phosphoserine255 def: "Protein HS90B_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:P08238] xref: UniProtKB:P08238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:B0012270 name: HS90B_HUMAN-Phosphoserine261 def: "Protein HS90B_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:P08238] xref: UniProtKB:P08238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:B0012271 name: HS90B_HUMAN-Phosphothreonine297 def: "Protein HS90B_HUMAN with the residue 297 substituted with Phosphothreonine" [UniProtKB:P08238] xref: UniProtKB:P08238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004355 ! nitric-oxide synthase regulator activity relationship: has_function CCO:F0004601 ! TPR domain binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:B0012272 name: HS90B_HUMAN-Phosphotyrosine484 def: "Protein HS90B_HUMAN with the residue 484 substituted with Phosphotyrosine" [UniProtKB:P08238] xref: UniProtKB:P08238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:B0012273 name: HS90B_HUMAN-N6-acetyllysine624 def: "Protein HS90B_HUMAN with the residue 624 substituted with N6-acetyllysine" [UniProtKB:P08238] xref: UniProtKB:P08238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:B0012274 name: HSP71_HUMAN-Phosphotyrosine611 def: "Protein HSP71_HUMAN with the residue 611 substituted with Phosphotyrosine" [UniProtKB:P08107] xref: UniProtKB:P08107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: transformation_of CCO:B0005822 ! HSP71_HUMAN [Term] id: CCO:B0012275 name: HSP71_HUMAN-Phosphoserine631 def: "Protein HSP71_HUMAN with the residue 631 substituted with Phosphoserine" [UniProtKB:P08107] xref: UniProtKB:P08107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005822 ! HSP71_HUMAN [Term] id: CCO:B0012276 name: HSP7C_HUMAN-Phosphotyrosine15 def: "Protein HSP7C_HUMAN with the residue 15 substituted with Phosphotyrosine" [UniProtKB:P11142] xref: UniProtKB:P11142 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:B0012277 name: HSP7C_HUMAN-Phosphoserine153 def: "Protein HSP7C_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:P11142] xref: UniProtKB:P11142 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:B0012278 name: HSP7C_HUMAN-Phosphothreonine477 def: "Protein HSP7C_HUMAN with the residue 477 substituted with Phosphothreonine" [UniProtKB:P11142] xref: UniProtKB:P11142 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:B0012279 name: HSPB1_HUMAN-Phosphoserine15 def: "Protein HSPB1_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:P04792] xref: UniProtKB:P04792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:B0012280 name: HSPB1_HUMAN-Phosphoserine26 def: "Protein HSPB1_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:P04792] comment: By similarity xref: UniProtKB:P04792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000709 ! cell surface relationship: transformation_of CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:B0012281 name: HSPB1_HUMAN-Phosphoserine65 def: "Protein HSPB1_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:P04792] xref: UniProtKB:P04792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:B0012282 name: HSPB1_HUMAN-Phosphoserine78 def: "Protein HSPB1_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:P04792] xref: UniProtKB:P04792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:B0012283 name: HSPB1_HUMAN-Phosphoserine82 def: "Protein HSPB1_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:P04792] xref: UniProtKB:P04792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:B0012284 name: HSPB1_HUMAN-Phosphoserine83 def: "Protein HSPB1_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P04792] xref: UniProtKB:P04792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:B0012285 name: HSPB1_HUMAN-N6-acetyllysine123 def: "Protein HSPB1_HUMAN with the residue 123 substituted with N6-acetyllysine" [UniProtKB:P04792] xref: UniProtKB:P04792 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:B0012286 name: HTAI2_HUMAN-Phosphoserine45 def: "Protein HTAI2_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q9BUP3] comment: By similarity xref: UniProtKB:Q9BUP3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002098 ! HTAI2_HUMAN [Term] id: CCO:B0012287 name: HUWE1_HUMAN-Phosphoserine1395 def: "Protein HUWE1_HUMAN with the residue 1395 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012288 name: HUWE1_HUMAN-Phosphoserine1907 def: "Protein HUWE1_HUMAN with the residue 1907 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012289 name: HUWE1_HUMAN-Phosphoserine2362 def: "Protein HUWE1_HUMAN with the residue 2362 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012290 name: HUWE1_HUMAN-Phosphoserine2377 def: "Protein HUWE1_HUMAN with the residue 2377 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012291 name: HUWE1_HUMAN-Phosphoserine2887 def: "Protein HUWE1_HUMAN with the residue 2887 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012292 name: HUWE1_HUMAN-Phosphoserine2918 def: "Protein HUWE1_HUMAN with the residue 2918 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012293 name: HUWE1_HUMAN-Phosphoserine3757 def: "Protein HUWE1_HUMAN with the residue 3757 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] comment: By similarity xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012294 name: HUWE1_HUMAN-Phosphoserine3797 def: "Protein HUWE1_HUMAN with the residue 3797 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012295 name: HUWE1_HUMAN-Phosphoserine3808 def: "Protein HUWE1_HUMAN with the residue 3808 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012296 name: HUWE1_HUMAN-Phosphoserine3816 def: "Protein HUWE1_HUMAN with the residue 3816 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012297 name: HUWE1_HUMAN-Phosphothreonine3822 def: "Protein HUWE1_HUMAN with the residue 3822 substituted with Phosphothreonine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012298 name: HUWE1_HUMAN-Phosphoserine3919 def: "Protein HUWE1_HUMAN with the residue 3919 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012299 name: HUWE1_HUMAN-Phosphothreonine3924 def: "Protein HUWE1_HUMAN with the residue 3924 substituted with Phosphothreonine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012300 name: HUWE1_HUMAN-Phosphothreonine3927 def: "Protein HUWE1_HUMAN with the residue 3927 substituted with Phosphothreonine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012301 name: HUWE1_HUMAN-Phosphotyrosine4271 def: "Protein HUWE1_HUMAN with the residue 4271 substituted with Phosphotyrosine" [UniProtKB:Q7Z6Z7] comment: By similarity xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0012302 name: IF2B_HUMAN-Phosphoserine2 def: "Protein IF2B_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P20042] xref: UniProtKB:P20042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000416 ! eukaryotic translation initiation factor 2 complex relationship: transformation_of CCO:B0006090 ! IF2B_HUMAN [Term] id: CCO:B0012303 name: IF2B_HUMAN-Phosphoserine67 def: "Protein IF2B_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:P20042] comment: By similarity xref: UniProtKB:P20042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006090 ! IF2B_HUMAN [Term] id: CCO:B0012333 name: IF4G2_HUMAN-N-acetylmethionine1 def: "Protein IF4G2_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P78344] xref: UniProtKB:P78344 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: transformation_of CCO:B0001699 ! IF4G2_HUMAN [Term] id: CCO:B0012334 name: IF4G2_HUMAN-Phosphoserine395 def: "Protein IF4G2_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:P78344] xref: UniProtKB:P78344 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001699 ! IF4G2_HUMAN [Term] id: CCO:B0012335 name: IF4G2_HUMAN-Phosphothreonine508 def: "Protein IF4G2_HUMAN with the residue 508 substituted with Phosphothreonine" [UniProtKB:P78344] xref: UniProtKB:P78344 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001699 ! IF4G2_HUMAN [Term] id: CCO:B0012336 name: IGF1R_HUMAN-Phosphotyrosine980 def: "Protein IGF1R_HUMAN with the residue 980 substituted with Phosphotyrosine" [UniProtKB:P08069] comment: by autocatalysis; xref: UniProtKB:P08069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001497 ! IGF1R_HUMAN [Term] id: CCO:B0012337 name: IGF1R_HUMAN-Phosphotyrosine1161 def: "Protein IGF1R_HUMAN with the residue 1161 substituted with Phosphotyrosine" [UniProtKB:P08069] comment: by autocatalysis; By similarity xref: UniProtKB:P08069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001347 ! insulin-like growth factor receptor activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004919 ! insulin-like growth factor I binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005873 ! phosphoinositide 3-kinase binding relationship: has_function CCO:F0005874 ! insulin binding relationship: has_function CCO:F0005875 ! insulin receptor substrate binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001497 ! IGF1R_HUMAN [Term] id: CCO:B0012338 name: IGF1R_HUMAN-Phosphotyrosine1165 def: "Protein IGF1R_HUMAN with the residue 1165 substituted with Phosphotyrosine" [UniProtKB:P08069] comment: by autocatalysis; By similarity xref: UniProtKB:P08069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001497 ! IGF1R_HUMAN [Term] id: CCO:B0012339 name: IGF1R_HUMAN-Phosphotyrosine1166 def: "Protein IGF1R_HUMAN with the residue 1166 substituted with Phosphotyrosine" [UniProtKB:P08069] comment: by autocatalysis; By similarity xref: UniProtKB:P08069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001497 ! IGF1R_HUMAN [Term] id: CCO:B0012340 name: IKBA_HUMAN-Phosphoserine32 def: "Protein IKBA_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:P25963] comment: by IKKA and IKKE; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0012341 name: IKBA_HUMAN-Phosphoserine36 def: "Protein IKBA_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P25963] comment: by IKKA, IKKB and IKKE; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0012342 name: IKBA_HUMAN-Phosphotyrosine42 def: "Protein IKBA_HUMAN with the residue 42 substituted with Phosphotyrosine" [UniProtKB:P25963] comment: by Tyr-kinases; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0012343 name: IKBB_HUMAN-Phosphoserine19 def: "Protein IKBB_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q15653] comment: By similarity xref: UniProtKB:Q15653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:B0012344 name: IKBB_HUMAN-Phosphoserine23 def: "Protein IKBB_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q15653] comment: By similarity xref: UniProtKB:Q15653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:B0012347 name: IKKA_HUMAN-Phosphothreonine23 def: "Protein IKKA_HUMAN with the residue 23 substituted with Phosphothreonine" [UniProtKB:O15111] comment: by PKB/AKT1; xref: UniProtKB:O15111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001856 ! IkappaB kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:B0012348 name: IKKA_HUMAN-Phosphoserine176 def: "Protein IKKA_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:O15111] comment: by MAP3K14; xref: UniProtKB:O15111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:B0012349 name: IKKB_HUMAN-Phosphothreonine23 def: "Protein IKKB_HUMAN with the residue 23 substituted with Phosphothreonine" [UniProtKB:O14920] comment: By similarity xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012350 name: IKKB_HUMAN-Phosphoserine177 def: "Protein IKKB_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:O14920] xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012351 name: IKKB_HUMAN-Phosphoserine181 def: "Protein IKKB_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:O14920] xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012352 name: IKKB_HUMAN-Phosphoserine670 def: "Protein IKKB_HUMAN with the residue 670 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012353 name: IKKB_HUMAN-Phosphoserine672 def: "Protein IKKB_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012354 name: IKKB_HUMAN-Phosphoserine675 def: "Protein IKKB_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012355 name: IKKB_HUMAN-Phosphoserine682 def: "Protein IKKB_HUMAN with the residue 682 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012356 name: IKKB_HUMAN-Phosphoserine689 def: "Protein IKKB_HUMAN with the residue 689 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012357 name: IKKB_HUMAN-Phosphoserine692 def: "Protein IKKB_HUMAN with the residue 692 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012358 name: IKKB_HUMAN-Phosphoserine695 def: "Protein IKKB_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012359 name: IKKB_HUMAN-Phosphoserine697 def: "Protein IKKB_HUMAN with the residue 697 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012360 name: IKKB_HUMAN-Phosphoserine705 def: "Protein IKKB_HUMAN with the residue 705 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012361 name: IKKB_HUMAN-Phosphoserine733 def: "Protein IKKB_HUMAN with the residue 733 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001856 ! IkappaB kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012362 name: IKKB_HUMAN-Phosphoserine740 def: "Protein IKKB_HUMAN with the residue 740 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012363 name: IKKB_HUMAN-Phosphoserine750 def: "Protein IKKB_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:O14920] comment: by autocatalysis; Probable xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0012364 name: IKKE_HUMAN-Phosphoserine172 def: "Protein IKKE_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q14164] xref: UniProtKB:Q14164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001070 ! NF-kappaB-inducing kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001856 ! IkappaB kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005523 ! IKKE_HUMAN [Term] id: CCO:B0012365 name: IL1R1_HUMAN-Phosphothreonine556 def: "Protein IL1R1_HUMAN with the residue 556 substituted with Phosphothreonine" [UniProtKB:P14778] xref: UniProtKB:P14778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005325 ! IL1R1_HUMAN [Term] id: CCO:B0012366 name: ILF3_HUMAN-Phosphoserine62 def: "Protein ILF3_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012367 name: ILF3_HUMAN-Phosphoserine190 def: "Protein ILF3_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012368 name: ILF3_HUMAN-Phosphoserine382 def: "Protein ILF3_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012369 name: ILF3_HUMAN-Phosphoserine384 def: "Protein ILF3_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012370 name: ILF3_HUMAN-Phosphoserine482 def: "Protein ILF3_HUMAN with the residue 482 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012371 name: ILF3_HUMAN-Phosphothreonine592 def: "Protein ILF3_HUMAN with the residue 592 substituted with Phosphothreonine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012372 name: ILF3_HUMAN-Omega-N-methylated arginine609 def: "Protein ILF3_HUMAN with the residue 609 substituted with Omega-N-methylated arginine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012373 name: ILF3_HUMAN-Phosphoserine812 def: "Protein ILF3_HUMAN with the residue 812 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0012374 name: ILKAP_HUMAN-Phosphoserine13 def: "Protein ILKAP_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:Q9H0C8] xref: UniProtKB:Q9H0C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002123 ! ILKAP_HUMAN [Term] id: CCO:B0012375 name: IMA2_HUMAN-Phosphoserine24 def: "Protein IMA2_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:P52292] xref: UniProtKB:P52292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001657 ! IMA2_HUMAN [Term] id: CCO:B0012376 name: IMA2_HUMAN-Phosphoserine62 def: "Protein IMA2_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:P52292] xref: UniProtKB:P52292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001657 ! IMA2_HUMAN [Term] id: CCO:B0012377 name: IMA2_HUMAN-Phosphoserine490 def: "Protein IMA2_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:P52292] xref: UniProtKB:P52292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001742 ! nuclear localization sequence binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001657 ! IMA2_HUMAN [Term] id: CCO:B0012378 name: IMA3_HUMAN-Phosphoserine60 def: "Protein IMA3_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:O00505] xref: UniProtKB:O00505 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001742 ! nuclear localization sequence binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005931 ! IMA3_HUMAN [Term] id: CCO:B0012379 name: IMB1_HUMAN-N-acetylmethionine1 def: "Protein IMB1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q14974] xref: UniProtKB:Q14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005409 ! IMB1_HUMAN [Term] id: CCO:B0012380 name: IMMT_HUMAN-N6-acetyllysine506 def: "Protein IMMT_HUMAN with the residue 506 substituted with N6-acetyllysine" [UniProtKB:Q16891] comment: By similarity xref: UniProtKB:Q16891 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:B0012381 name: INCE_HUMAN-Phosphotyrosine73 def: "Protein INCE_HUMAN with the residue 73 substituted with Phosphotyrosine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012382 name: INCE_HUMAN-Phosphoserine119 def: "Protein INCE_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012383 name: INCE_HUMAN-Phosphoserine142 def: "Protein INCE_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012384 name: INCE_HUMAN-Phosphoserine143 def: "Protein INCE_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012385 name: INCE_HUMAN-Phosphoserine148 def: "Protein INCE_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012386 name: INCE_HUMAN-Phosphoserine197 def: "Protein INCE_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012387 name: INCE_HUMAN-Phosphothreonine199 def: "Protein INCE_HUMAN with the residue 199 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012388 name: INCE_HUMAN-Phosphothreonine213 def: "Protein INCE_HUMAN with the residue 213 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012389 name: INCE_HUMAN-Phosphoserine214 def: "Protein INCE_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012390 name: INCE_HUMAN-Phosphothreonine219 def: "Protein INCE_HUMAN with the residue 219 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012391 name: INCE_HUMAN-Phosphoserine230 def: "Protein INCE_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012392 name: INCE_HUMAN-Phosphothreonine239 def: "Protein INCE_HUMAN with the residue 239 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012393 name: INCE_HUMAN-Phosphoserine263 def: "Protein INCE_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012394 name: INCE_HUMAN-Phosphoserine269 def: "Protein INCE_HUMAN with the residue 269 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012395 name: INCE_HUMAN-Phosphoserine275 def: "Protein INCE_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012396 name: INCE_HUMAN-Phosphoserine291 def: "Protein INCE_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012397 name: INCE_HUMAN-Phosphothreonine292 def: "Protein INCE_HUMAN with the residue 292 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012398 name: INCE_HUMAN-Phosphothreonine294 def: "Protein INCE_HUMAN with the residue 294 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012399 name: INCE_HUMAN-Phosphoserine296 def: "Protein INCE_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: located_in CCO:C0002171 ! centromeric heterochromatin relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012400 name: INCE_HUMAN-Phosphothreonine298 def: "Protein INCE_HUMAN with the residue 298 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012401 name: INCE_HUMAN-Phosphoserine306 def: "Protein INCE_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012402 name: INCE_HUMAN-Phosphoserine312 def: "Protein INCE_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012403 name: INCE_HUMAN-Phosphoserine314 def: "Protein INCE_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012404 name: INCE_HUMAN-Phosphoserine421 def: "Protein INCE_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012405 name: INCE_HUMAN-Phosphothreonine424 def: "Protein INCE_HUMAN with the residue 424 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012406 name: INCE_HUMAN-Phosphoserine481 def: "Protein INCE_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012412 name: INCE_HUMAN-Phosphoserine899 def: "Protein INCE_HUMAN with the residue 899 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0012414 name: ING4_HUMAN-N6-acetyllysine127 def: "Protein ING4_HUMAN with the residue 127 substituted with N6-acetyllysine" [UniProtKB:Q9UNL4] xref: UniProtKB:Q9UNL4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002234 ! ING4_HUMAN [Term] id: CCO:B0012415 name: ING4_HUMAN-N6-acetyllysine129 def: "Protein ING4_HUMAN with the residue 129 substituted with N6-acetyllysine" [UniProtKB:Q9UNL4] xref: UniProtKB:Q9UNL4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002234 ! ING4_HUMAN [Term] id: CCO:B0012416 name: ING4_HUMAN-N6-acetyllysine146 def: "Protein ING4_HUMAN with the residue 146 substituted with N6-acetyllysine" [UniProtKB:Q9UNL4] xref: UniProtKB:Q9UNL4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002234 ! ING4_HUMAN [Term] id: CCO:B0012417 name: ING4_HUMAN-N6-acetyllysine148 def: "Protein ING4_HUMAN with the residue 148 substituted with N6-acetyllysine" [UniProtKB:Q9UNL4] xref: UniProtKB:Q9UNL4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002234 ! ING4_HUMAN [Term] id: CCO:B0012418 name: ING5_HUMAN-Phosphoserine118 def: "Protein ING5_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q8WYH8] xref: UniProtKB:Q8WYH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005284 ! ING5_HUMAN [Term] id: CCO:B0012419 name: INSR_HUMAN-Phosphotyrosine992 def: "Protein INSR_HUMAN with the residue 992 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; Probable xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012420 name: INSR_HUMAN-Phosphotyrosine999 def: "Protein INSR_HUMAN with the residue 999 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001346 ! insulin receptor activity relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004919 ! insulin-like growth factor I binding relationship: has_function CCO:F0004920 ! insulin-like growth factor II binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0005873 ! phosphoinositide 3-kinase binding relationship: has_function CCO:F0005874 ! insulin binding relationship: has_function CCO:F0005875 ! insulin receptor substrate binding relationship: has_function CCO:F0008108 ! PTB domain binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012421 name: INSR_HUMAN-Phosphotyrosine1011 def: "Protein INSR_HUMAN with the residue 1011 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; Probable xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012422 name: INSR_HUMAN-Phosphotyrosine1185 def: "Protein INSR_HUMAN with the residue 1185 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012423 name: INSR_HUMAN-Phosphotyrosine1189 def: "Protein INSR_HUMAN with the residue 1189 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012424 name: INSR_HUMAN-Phosphotyrosine1190 def: "Protein INSR_HUMAN with the residue 1190 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012425 name: INSR_HUMAN-Phosphotyrosine1355 def: "Protein INSR_HUMAN with the residue 1355 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012426 name: INSR_HUMAN-Phosphotyrosine1361 def: "Protein INSR_HUMAN with the residue 1361 substituted with Phosphotyrosine" [UniProtKB:P06213] comment: by autocatalysis; xref: UniProtKB:P06213 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:B0012427 name: IPO7_HUMAN-N-acetylmethionine1 def: "Protein IPO7_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:O95373] xref: UniProtKB:O95373 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005661 ! IPO7_HUMAN [Term] id: CCO:B0012428 name: IPO7_HUMAN-Phosphotyrosine311 def: "Protein IPO7_HUMAN with the residue 311 substituted with Phosphotyrosine" [UniProtKB:O95373] xref: UniProtKB:O95373 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005661 ! IPO7_HUMAN [Term] id: CCO:B0012429 name: ITSN2_HUMAN-Phosphoserine209 def: "Protein ITSN2_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q9NZM3] comment: By similarity xref: UniProtKB:Q9NZM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:B0012430 name: ITSN2_HUMAN-Phosphotyrosine552 def: "Protein ITSN2_HUMAN with the residue 552 substituted with Phosphotyrosine" [UniProtKB:Q9NZM3] xref: UniProtKB:Q9NZM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:B0012431 name: ITSN2_HUMAN-Phosphotyrosine858 def: "Protein ITSN2_HUMAN with the residue 858 substituted with Phosphotyrosine" [UniProtKB:Q9NZM3] xref: UniProtKB:Q9NZM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:B0012432 name: ITSN2_HUMAN-Phosphotyrosine967 def: "Protein ITSN2_HUMAN with the residue 967 substituted with Phosphotyrosine" [UniProtKB:Q9NZM3] xref: UniProtKB:Q9NZM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:B0012433 name: JAK2_HUMAN-Phosphotyrosine1007 def: "Protein JAK2_HUMAN with the residue 1007 substituted with Phosphotyrosine" [UniProtKB:O60674] comment: by autocatalysis; xref: UniProtKB:O60674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001083 ! Janus kinase activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0001414 ! JAK2_HUMAN [Term] id: CCO:B0012434 name: JAK3_HUMAN-Phosphothreonine8 def: "Protein JAK3_HUMAN with the residue 8 substituted with Phosphothreonine" [UniProtKB:P52333] comment: By similarity xref: UniProtKB:P52333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001083 ! Janus kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005612 ! JAK3_HUMAN [Term] id: CCO:B0012435 name: JAK3_HUMAN-Phosphotyrosine785 def: "Protein JAK3_HUMAN with the residue 785 substituted with Phosphotyrosine" [UniProtKB:P52333] xref: UniProtKB:P52333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005612 ! JAK3_HUMAN [Term] id: CCO:B0012436 name: JAK3_HUMAN-Phosphotyrosine980 def: "Protein JAK3_HUMAN with the residue 980 substituted with Phosphotyrosine" [UniProtKB:P52333] comment: by autocatalysis; By similarity xref: UniProtKB:P52333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005612 ! JAK3_HUMAN [Term] id: CCO:B0012437 name: JHD1A_HUMAN-Phosphoserine28 def: "Protein JHD1A_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0012438 name: JHD1A_HUMAN-Phosphothreonine534 def: "Protein JHD1A_HUMAN with the residue 534 substituted with Phosphothreonine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0012439 name: JHD1A_HUMAN-Phosphothreonine632 def: "Protein JHD1A_HUMAN with the residue 632 substituted with Phosphothreonine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0012440 name: JIP3_HUMAN-Phosphothreonine265 def: "Protein JIP3_HUMAN with the residue 265 substituted with Phosphothreonine" [UniProtKB:Q9UPT6] comment: by MAPK; By similarity xref: UniProtKB:Q9UPT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006034 ! JIP3_HUMAN [Term] id: CCO:B0012441 name: JIP3_HUMAN-Phosphoserine267 def: "Protein JIP3_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q9UPT6] comment: By similarity xref: UniProtKB:Q9UPT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006034 ! JIP3_HUMAN [Term] id: CCO:B0012442 name: JIP3_HUMAN-Phosphothreonine275 def: "Protein JIP3_HUMAN with the residue 275 substituted with Phosphothreonine" [UniProtKB:Q9UPT6] comment: by MAPK; By similarity xref: UniProtKB:Q9UPT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006034 ! JIP3_HUMAN [Term] id: CCO:B0012443 name: JIP3_HUMAN-Phosphothreonine286 def: "Protein JIP3_HUMAN with the residue 286 substituted with Phosphothreonine" [UniProtKB:Q9UPT6] comment: by MAPK; By similarity xref: UniProtKB:Q9UPT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006034 ! JIP3_HUMAN [Term] id: CCO:B0012444 name: JIP3_HUMAN-Phosphoserine365 def: "Protein JIP3_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q9UPT6] comment: By similarity xref: UniProtKB:Q9UPT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001384 ! MAP-kinase scaffold activity relationship: has_function CCO:F0004206 ! kinesin binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006034 ! JIP3_HUMAN [Term] id: CCO:B0012445 name: JIP3_HUMAN-Phosphoserine585 def: "Protein JIP3_HUMAN with the residue 585 substituted with Phosphoserine" [UniProtKB:Q9UPT6] xref: UniProtKB:Q9UPT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006034 ! JIP3_HUMAN [Term] id: CCO:B0012446 name: JIP3_HUMAN-Phosphoserine676 def: "Protein JIP3_HUMAN with the residue 676 substituted with Phosphoserine" [UniProtKB:Q9UPT6] comment: By similarity xref: UniProtKB:Q9UPT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006034 ! JIP3_HUMAN [Term] id: CCO:B0012447 name: JUNB_HUMAN-Phosphothreonine255 def: "Protein JUNB_HUMAN with the residue 255 substituted with Phosphothreonine" [UniProtKB:P17275] xref: UniProtKB:P17275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001530 ! JUNB_HUMAN [Term] id: CCO:B0012448 name: JUNB_HUMAN-Phosphoserine259 def: "Protein JUNB_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:P17275] xref: UniProtKB:P17275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001530 ! JUNB_HUMAN [Term] id: CCO:B0012449 name: JUN_HUMAN-Phosphoserine63 def: "Protein JUN_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:P05412] comment: by MAPK8; xref: UniProtKB:P05412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001487 ! JUN_HUMAN [Term] id: CCO:B0012450 name: JUN_HUMAN-Phosphoserine73 def: "Protein JUN_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:P05412] comment: by MAPK8; xref: UniProtKB:P05412 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001487 ! JUN_HUMAN [Term] id: CCO:B0012451 name: K0087_HUMAN-Phosphoserine6 def: "Protein K0087_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q14695] xref: UniProtKB:Q14695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006280 ! K0087_HUMAN [Term] id: CCO:B0012452 name: K0087_HUMAN-Phosphoserine7 def: "Protein K0087_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q14695] xref: UniProtKB:Q14695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006280 ! K0087_HUMAN [Term] id: CCO:B0012453 name: K1267_HUMAN-Phosphoserine1082 def: "Protein K1267_HUMAN with the residue 1082 substituted with Phosphoserine" [UniProtKB:Q7Z3B3] xref: UniProtKB:Q7Z3B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005600 ! K1267_HUMAN [Term] id: CCO:B0012454 name: K1683_HUMAN-Phosphotyrosine302 def: "Protein K1683_HUMAN with the residue 302 substituted with Phosphotyrosine" [UniProtKB:Q9H0B3] xref: UniProtKB:Q9H0B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005254 ! K1683_HUMAN [Term] id: CCO:B0012455 name: K1683_HUMAN-Phosphothreonine307 def: "Protein K1683_HUMAN with the residue 307 substituted with Phosphothreonine" [UniProtKB:Q9H0B3] xref: UniProtKB:Q9H0B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005254 ! K1683_HUMAN [Term] id: CCO:B0012456 name: K1683_HUMAN-Phosphothreonine314 def: "Protein K1683_HUMAN with the residue 314 substituted with Phosphothreonine" [UniProtKB:Q9H0B3] xref: UniProtKB:Q9H0B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005254 ! K1683_HUMAN [Term] id: CCO:B0012457 name: K1683_HUMAN-Phosphoserine367 def: "Protein K1683_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q9H0B3] xref: UniProtKB:Q9H0B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005254 ! K1683_HUMAN [Term] id: CCO:B0012458 name: K1C17_HUMAN-Phosphoserine32 def: "Protein K1C17_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q04695] xref: UniProtKB:Q04695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005844 ! K1C17_HUMAN [Term] id: CCO:B0012459 name: K1C17_HUMAN-Phosphoserine319 def: "Protein K1C17_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q04695] comment: By similarity xref: UniProtKB:Q04695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0005844 ! K1C17_HUMAN [Term] id: CCO:B0012460 name: K1C18_HUMAN-N-acetylserine2 def: "Protein K1C18_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P05783] xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012461 name: K1C18_HUMAN-Phosphoserine7 def: "Protein K1C18_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:P05783] xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012462 name: K1C18_HUMAN-Phosphothreonine8 def: "Protein K1C18_HUMAN with the residue 8 substituted with Phosphothreonine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012463 name: K1C18_HUMAN-Phosphothreonine11 def: "Protein K1C18_HUMAN with the residue 11 substituted with Phosphothreonine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012464 name: K1C18_HUMAN-Phosphoserine15 def: "Protein K1C18_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:P05783] xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0001886 ! keratin filament relationship: located_in CCO:C0002178 ! centriolar satellite relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012465 name: K1C18_HUMAN-Phosphoserine18 def: "Protein K1C18_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:P05783] xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012466 name: K1C18_HUMAN-Phosphoserine30 def: "Protein K1C18_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012467 name: K1C18_HUMAN-Phosphoserine31 def: "Protein K1C18_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012468 name: K1C18_HUMAN-Phosphoserine34 def: "Protein K1C18_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P05783] comment: by CDC2; xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012469 name: K1C18_HUMAN-Phosphotyrosine36 def: "Protein K1C18_HUMAN with the residue 36 substituted with Phosphotyrosine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012470 name: K1C18_HUMAN-Phosphoserine42 def: "Protein K1C18_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012471 name: K1C18_HUMAN-Phosphoserine53 def: "Protein K1C18_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:P05783] comment: by CAMK, PKC/PRKCE and STK6; xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012472 name: K1C18_HUMAN-Phosphoserine60 def: "Protein K1C18_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:P05783] xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012473 name: K1C18_HUMAN-Phosphoserine401 def: "Protein K1C18_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012474 name: K1C18_HUMAN-Phosphothreonine404 def: "Protein K1C18_HUMAN with the residue 404 substituted with Phosphothreonine" [UniProtKB:P05783] comment: By similarity xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0012475 name: K2C1_HUMAN-Phosphoserine21 def: "Protein K2C1_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P04264] xref: UniProtKB:P04264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005823 ! K2C1_HUMAN [Term] id: CCO:B0012476 name: K2C1_HUMAN-Phosphoserine66 def: "Protein K2C1_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:P04264] comment: By similarity xref: UniProtKB:P04264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005823 ! K2C1_HUMAN [Term] id: CCO:B0012477 name: K2C1_HUMAN-Phosphotyrosine295 def: "Protein K2C1_HUMAN with the residue 295 substituted with Phosphotyrosine" [UniProtKB:P04264] xref: UniProtKB:P04264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005823 ! K2C1_HUMAN [Term] id: CCO:B0012478 name: K2C1_HUMAN-Phosphothreonine297 def: "Protein K2C1_HUMAN with the residue 297 substituted with Phosphothreonine" [UniProtKB:P04264] xref: UniProtKB:P04264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005823 ! K2C1_HUMAN [Term] id: CCO:B0012479 name: K2C5_HUMAN-Phosphoserine64 def: "Protein K2C5_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:P13647] comment: By similarity xref: UniProtKB:P13647 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005811 ! K2C5_HUMAN [Term] id: CCO:B0012480 name: K2C6A_HUMAN-Phosphoserine60 def: "Protein K2C6A_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:P02538] comment: By similarity xref: UniProtKB:P02538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0005821 ! K2C6A_HUMAN [Term] id: CCO:B0012481 name: K2C7_HUMAN-Phosphoserine14 def: "Protein K2C7_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:P08729] comment: By similarity xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0012482 name: K2C7_HUMAN-Omega-N-methylated arginine20 def: "Protein K2C7_HUMAN with the residue 20 substituted with Omega-N-methylated arginine" [UniProtKB:P08729] xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0012483 name: K2C7_HUMAN-Phosphoserine45 def: "Protein K2C7_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:P08729] xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0012484 name: K2C7_HUMAN-Phosphoserine254 def: "Protein K2C7_HUMAN with the residue 254 substituted with Phosphoserine" [UniProtKB:P08729] xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0012485 name: K2C7_HUMAN-Phosphotyrosine375 def: "Protein K2C7_HUMAN with the residue 375 substituted with Phosphotyrosine" [UniProtKB:P08729] xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0012486 name: K2C7_HUMAN-Phosphoserine380 def: "Protein K2C7_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:P08729] xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0012487 name: K2C8_HUMAN-Phosphoserine9 def: "Protein K2C8_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012488 name: K2C8_HUMAN-Phosphoserine13 def: "Protein K2C8_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012489 name: K2C8_HUMAN-Phosphoserine21 def: "Protein K2C8_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012490 name: K2C8_HUMAN-Phosphoserine22 def: "Protein K2C8_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012491 name: K2C8_HUMAN-Phosphoserine24 def: "Protein K2C8_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012492 name: K2C8_HUMAN-Phosphothreonine26 def: "Protein K2C8_HUMAN with the residue 26 substituted with Phosphothreonine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012493 name: K2C8_HUMAN-Phosphoserine27 def: "Protein K2C8_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000934 ! Z disc relationship: located_in CCO:C0001638 ! sarcolemma relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012494 name: K2C8_HUMAN-Phosphoserine34 def: "Protein K2C8_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012495 name: K2C8_HUMAN-Phosphoserine37 def: "Protein K2C8_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012496 name: K2C8_HUMAN-Phosphoserine43 def: "Protein K2C8_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012497 name: K2C8_HUMAN-Phosphoserine44 def: "Protein K2C8_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012498 name: K2C8_HUMAN-Phosphoserine74 def: "Protein K2C8_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:P05787] comment: by MAPK; xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012499 name: K2C8_HUMAN-Phosphoserine253 def: "Protein K2C8_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012500 name: K2C8_HUMAN-Phosphoserine330 def: "Protein K2C8_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012501 name: K2C8_HUMAN-Phosphoserine417 def: "Protein K2C8_HUMAN with the residue 417 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012502 name: K2C8_HUMAN-Phosphoserine424 def: "Protein K2C8_HUMAN with the residue 424 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012503 name: K2C8_HUMAN-Phosphoserine432 def: "Protein K2C8_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:P05787] comment: by CaMK2 and MAPK; xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012504 name: K2C8_HUMAN-Phosphoserine451 def: "Protein K2C8_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012505 name: K2C8_HUMAN-Phosphoserine475 def: "Protein K2C8_HUMAN with the residue 475 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012506 name: K2C8_HUMAN-Phosphoserine478 def: "Protein K2C8_HUMAN with the residue 478 substituted with Phosphoserine" [UniProtKB:P05787] comment: By similarity xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0012507 name: KAP0_HUMAN-N-acetylmethionine1 def: "Protein KAP0_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P10644] xref: UniProtKB:P10644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005298 ! KAP0_HUMAN [Term] id: CCO:B0012508 name: KAP0_HUMAN-Phosphoserine77 def: "Protein KAP0_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P10644] comment: By similarity xref: UniProtKB:P10644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005298 ! KAP0_HUMAN [Term] id: CCO:B0012509 name: KAP0_HUMAN-Phosphoserine83 def: "Protein KAP0_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P10644] xref: UniProtKB:P10644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005298 ! KAP0_HUMAN [Term] id: CCO:B0012510 name: KAP0_HUMAN-Phosphoserine101 def: "Protein KAP0_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:P10644] comment: By similarity xref: UniProtKB:P10644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005298 ! KAP0_HUMAN [Term] id: CCO:B0012511 name: KC1E_HUMAN-Phosphothreonine362 def: "Protein KC1E_HUMAN with the residue 362 substituted with Phosphothreonine" [UniProtKB:P49674] xref: UniProtKB:P49674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005272 ! KC1E_HUMAN [Term] id: CCO:B0012512 name: KC1E_HUMAN-Phosphoserine363 def: "Protein KC1E_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:P49674] xref: UniProtKB:P49674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001051 ! casein kinase I activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005272 ! KC1E_HUMAN [Term] id: CCO:B0012513 name: KGP2_HUMAN-Nitrated tyrosine354 def: "Protein KGP2_HUMAN with the residue 354 substituted with Nitrated tyrosine" [UniProtKB:Q13237] xref: UniProtKB:Q13237 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001059 ! cGMP-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001747 ! KGP2_HUMAN [Term] id: CCO:B0012514 name: KHDR1_HUMAN-Phosphoserine18 def: "Protein KHDR1_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q07666] xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012515 name: KHDR1_HUMAN-Phosphoserine20 def: "Protein KHDR1_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q07666] xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012516 name: KHDR1_HUMAN-Phosphothreonine33 def: "Protein KHDR1_HUMAN with the residue 33 substituted with Phosphothreonine" [UniProtKB:Q07666] xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012517 name: KHDR1_HUMAN-dimethylarginine45 def: "Protein KHDR1_HUMAN with the residue 45 substituted with dimethylarginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012518 name: KHDR1_HUMAN-dimethylarginine52 def: "Protein KHDR1_HUMAN with the residue 52 substituted with dimethylarginine" [UniProtKB:Q07666] comment: partial; by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012519 name: KHDR1_HUMAN-arginine291 def: "Protein KHDR1_HUMAN with the residue 291 substituted with arginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012520 name: KHDR1_HUMAN-dimethylarginine304 def: "Protein KHDR1_HUMAN with the residue 304 substituted with dimethylarginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012521 name: KHDR1_HUMAN-Omega-N-methylarginine310 def: "Protein KHDR1_HUMAN with the residue 310 substituted with Omega-N-methylarginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012522 name: KHDR1_HUMAN-Omega-N-methylarginine315 def: "Protein KHDR1_HUMAN with the residue 315 substituted with Omega-N-methylarginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012523 name: KHDR1_HUMAN-Omega-N-methylarginine320 def: "Protein KHDR1_HUMAN with the residue 320 substituted with Omega-N-methylarginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012524 name: KHDR1_HUMAN-Omega-N-methylarginine325 def: "Protein KHDR1_HUMAN with the residue 325 substituted with Omega-N-methylarginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012525 name: KHDR1_HUMAN-arginine331 def: "Protein KHDR1_HUMAN with the residue 331 substituted with arginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012526 name: KHDR1_HUMAN-Omega-N-methylarginine340 def: "Protein KHDR1_HUMAN with the residue 340 substituted with Omega-N-methylarginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012527 name: KHDR1_HUMAN-arginine346 def: "Protein KHDR1_HUMAN with the residue 346 substituted with arginine" [UniProtKB:Q07666] comment: by PRMT1; xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0012528 name: KHDR3_HUMAN-Phosphotyrosine5 def: "Protein KHDR3_HUMAN with the residue 5 substituted with Phosphotyrosine" [UniProtKB:O75525] xref: UniProtKB:O75525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005275 ! KHDR3_HUMAN [Term] id: CCO:B0012529 name: KI13B_HUMAN-Phosphoserine1410 def: "Protein KI13B_HUMAN with the residue 1410 substituted with Phosphoserine" [UniProtKB:Q9NQT8] xref: UniProtKB:Q9NQT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005849 ! KI13B_HUMAN [Term] id: CCO:B0012530 name: KI67_HUMAN-Phosphoserine108 def: "Protein KI67_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012531 name: KI67_HUMAN-Phosphoserine125 def: "Protein KI67_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012532 name: KI67_HUMAN-Phosphoserine128 def: "Protein KI67_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012533 name: KI67_HUMAN-Phosphoserine308 def: "Protein KI67_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012534 name: KI67_HUMAN-Phosphothreonine328 def: "Protein KI67_HUMAN with the residue 328 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012535 name: KI67_HUMAN-Phosphoserine357 def: "Protein KI67_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012536 name: KI67_HUMAN-Phosphoserine374 def: "Protein KI67_HUMAN with the residue 374 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012537 name: KI67_HUMAN-Phosphothreonine543 def: "Protein KI67_HUMAN with the residue 543 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012538 name: KI67_HUMAN-Phosphoserine579 def: "Protein KI67_HUMAN with the residue 579 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012539 name: KI67_HUMAN-Phosphoserine584 def: "Protein KI67_HUMAN with the residue 584 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012540 name: KI67_HUMAN-Phosphoserine648 def: "Protein KI67_HUMAN with the residue 648 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012541 name: KI67_HUMAN-Phosphoserine1098 def: "Protein KI67_HUMAN with the residue 1098 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012542 name: KI67_HUMAN-Phosphoserine1131 def: "Protein KI67_HUMAN with the residue 1131 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012543 name: KI67_HUMAN-Phosphothreonine1139 def: "Protein KI67_HUMAN with the residue 1139 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012544 name: KI67_HUMAN-Phosphothreonine1193 def: "Protein KI67_HUMAN with the residue 1193 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012545 name: KI67_HUMAN-Phosphoserine1207 def: "Protein KI67_HUMAN with the residue 1207 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012546 name: KI67_HUMAN-Phosphothreonine1233 def: "Protein KI67_HUMAN with the residue 1233 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012547 name: KI67_HUMAN-Phosphoserine1253 def: "Protein KI67_HUMAN with the residue 1253 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012548 name: KI67_HUMAN-Phosphothreonine1298 def: "Protein KI67_HUMAN with the residue 1298 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012549 name: KI67_HUMAN-Phosphoserine1302 def: "Protein KI67_HUMAN with the residue 1302 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012550 name: KI67_HUMAN-Phosphothreonine1327 def: "Protein KI67_HUMAN with the residue 1327 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012551 name: KI67_HUMAN-Phosphothreonine1335 def: "Protein KI67_HUMAN with the residue 1335 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012552 name: KI67_HUMAN-Phosphothreonine1355 def: "Protein KI67_HUMAN with the residue 1355 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012553 name: KI67_HUMAN-Phosphoserine1375 def: "Protein KI67_HUMAN with the residue 1375 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012554 name: KI67_HUMAN-Phosphoserine1376 def: "Protein KI67_HUMAN with the residue 1376 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012555 name: KI67_HUMAN-Phosphothreonine1557 def: "Protein KI67_HUMAN with the residue 1557 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012556 name: KI67_HUMAN-Phosphothreonine1569 def: "Protein KI67_HUMAN with the residue 1569 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012557 name: KI67_HUMAN-Phosphoserine1618 def: "Protein KI67_HUMAN with the residue 1618 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012558 name: KI67_HUMAN-Phosphoserine1629 def: "Protein KI67_HUMAN with the residue 1629 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012559 name: KI67_HUMAN-Phosphoserine1636 def: "Protein KI67_HUMAN with the residue 1636 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012560 name: KI67_HUMAN-Phosphoserine1679 def: "Protein KI67_HUMAN with the residue 1679 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012561 name: KI67_HUMAN-Phosphoserine1740 def: "Protein KI67_HUMAN with the residue 1740 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012562 name: KI67_HUMAN-Phosphothreonine1764 def: "Protein KI67_HUMAN with the residue 1764 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012563 name: KI67_HUMAN-Phosphothreonine1801 def: "Protein KI67_HUMAN with the residue 1801 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012564 name: KI67_HUMAN-Phosphoserine1815 def: "Protein KI67_HUMAN with the residue 1815 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012565 name: KI67_HUMAN-Phosphoserine1861 def: "Protein KI67_HUMAN with the residue 1861 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012566 name: KI67_HUMAN-Phosphothreonine1897 def: "Protein KI67_HUMAN with the residue 1897 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012567 name: KI67_HUMAN-Phosphothreonine1923 def: "Protein KI67_HUMAN with the residue 1923 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012568 name: KI67_HUMAN-Phosphoserine1937 def: "Protein KI67_HUMAN with the residue 1937 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012569 name: KI67_HUMAN-Phosphoserine2002 def: "Protein KI67_HUMAN with the residue 2002 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012570 name: KI67_HUMAN-Phosphothreonine2085 def: "Protein KI67_HUMAN with the residue 2085 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012571 name: KI67_HUMAN-Phosphoserine2105 def: "Protein KI67_HUMAN with the residue 2105 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012572 name: KI67_HUMAN-Phosphoserine2223 def: "Protein KI67_HUMAN with the residue 2223 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012573 name: KI67_HUMAN-Phosphothreonine2231 def: "Protein KI67_HUMAN with the residue 2231 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012574 name: KI67_HUMAN-Phosphothreonine2285 def: "Protein KI67_HUMAN with the residue 2285 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012575 name: KI67_HUMAN-Phosphothreonine2305 def: "Protein KI67_HUMAN with the residue 2305 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012576 name: KI67_HUMAN-Phosphothreonine2406 def: "Protein KI67_HUMAN with the residue 2406 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012577 name: KI67_HUMAN-Phosphoserine2505 def: "Protein KI67_HUMAN with the residue 2505 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012578 name: KI67_HUMAN-Phosphothreonine2508 def: "Protein KI67_HUMAN with the residue 2508 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012579 name: KI67_HUMAN-Phosphoserine2528 def: "Protein KI67_HUMAN with the residue 2528 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012580 name: KI67_HUMAN-Phosphoserine2708 def: "Protein KI67_HUMAN with the residue 2708 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012581 name: KI67_HUMAN-Phosphoserine2827 def: "Protein KI67_HUMAN with the residue 2827 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012582 name: KI67_HUMAN-Phosphoserine2828 def: "Protein KI67_HUMAN with the residue 2828 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0012583 name: KIF11_HUMAN-Phosphothreonine458 def: "Protein KIF11_HUMAN with the residue 458 substituted with Phosphothreonine" [UniProtKB:P52732] xref: UniProtKB:P52732 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001659 ! KIF11_HUMAN [Term] id: CCO:B0012584 name: KIF11_HUMAN-Phosphothreonine926 def: "Protein KIF11_HUMAN with the residue 926 substituted with Phosphothreonine" [UniProtKB:P52732] comment: by CDC2; xref: UniProtKB:P52732 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000436 ! spindle microtubule relationship: transformation_of CCO:B0001659 ! KIF11_HUMAN [Term] id: CCO:B0012585 name: KIF11_HUMAN-Phosphoserine931 def: "Protein KIF11_HUMAN with the residue 931 substituted with Phosphoserine" [UniProtKB:P52732] xref: UniProtKB:P52732 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001659 ! KIF11_HUMAN [Term] id: CCO:B0012586 name: KIF22_HUMAN-Phosphoserine452 def: "Protein KIF22_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:Q14807] xref: UniProtKB:Q14807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001792 ! KIF22_HUMAN [Term] id: CCO:B0012587 name: KIF22_HUMAN-Phosphoserine543 def: "Protein KIF22_HUMAN with the residue 543 substituted with Phosphoserine" [UniProtKB:Q14807] xref: UniProtKB:Q14807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001792 ! KIF22_HUMAN [Term] id: CCO:B0012588 name: KIF22_HUMAN-Phosphoserine562 def: "Protein KIF22_HUMAN with the residue 562 substituted with Phosphoserine" [UniProtKB:Q14807] xref: UniProtKB:Q14807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001792 ! KIF22_HUMAN [Term] id: CCO:B0012589 name: KIF22_HUMAN-Phosphoserine581 def: "Protein KIF22_HUMAN with the residue 581 substituted with Phosphoserine" [UniProtKB:Q14807] xref: UniProtKB:Q14807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001792 ! KIF22_HUMAN [Term] id: CCO:B0012590 name: KIF23_HUMAN-Phosphotyrosine29 def: "Protein KIF23_HUMAN with the residue 29 substituted with Phosphotyrosine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012591 name: KIF23_HUMAN-Phosphoserine155 def: "Protein KIF23_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012592 name: KIF23_HUMAN-Phosphoserine160 def: "Protein KIF23_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012593 name: KIF23_HUMAN-Phosphothreonine450 def: "Protein KIF23_HUMAN with the residue 450 substituted with Phosphothreonine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012594 name: KIF23_HUMAN-Phosphoserine682 def: "Protein KIF23_HUMAN with the residue 682 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012595 name: KIF23_HUMAN-Phosphoserine684 def: "Protein KIF23_HUMAN with the residue 684 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012596 name: KIF23_HUMAN-Phosphoserine686 def: "Protein KIF23_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012597 name: KIF23_HUMAN-Phosphothreonine738 def: "Protein KIF23_HUMAN with the residue 738 substituted with Phosphothreonine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012598 name: KIF23_HUMAN-Phosphoserine814 def: "Protein KIF23_HUMAN with the residue 814 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012599 name: KIF23_HUMAN-Phosphoserine867 def: "Protein KIF23_HUMAN with the residue 867 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012600 name: KIF23_HUMAN-Phosphoserine902 def: "Protein KIF23_HUMAN with the residue 902 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012601 name: KIF23_HUMAN-Phosphoserine911 def: "Protein KIF23_HUMAN with the residue 911 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012602 name: KIF23_HUMAN-Phosphoserine912 def: "Protein KIF23_HUMAN with the residue 912 substituted with Phosphoserine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0012603 name: KIF2C_HUMAN-Phosphoserine628 def: "Protein KIF2C_HUMAN with the residue 628 substituted with Phosphoserine" [UniProtKB:Q99661] xref: UniProtKB:Q99661 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002080 ! KIF2C_HUMAN [Term] id: CCO:B0012604 name: KIF2C_HUMAN-Phosphoserine629 def: "Protein KIF2C_HUMAN with the residue 629 substituted with Phosphoserine" [UniProtKB:Q99661] xref: UniProtKB:Q99661 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002080 ! KIF2C_HUMAN [Term] id: CCO:B0012605 name: KIF2C_HUMAN-Phosphoserine632 def: "Protein KIF2C_HUMAN with the residue 632 substituted with Phosphoserine" [UniProtKB:Q99661] xref: UniProtKB:Q99661 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002080 ! KIF2C_HUMAN [Term] id: CCO:B0012606 name: KIF2C_HUMAN-Phosphoserine633 def: "Protein KIF2C_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:Q99661] xref: UniProtKB:Q99661 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002080 ! KIF2C_HUMAN [Term] id: CCO:B0012607 name: KIF3A_HUMAN-Phosphoserine690 def: "Protein KIF3A_HUMAN with the residue 690 substituted with Phosphoserine" [UniProtKB:Q9Y496] xref: UniProtKB:Q9Y496 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0005880 ! KIF3A_HUMAN [Term] id: CCO:B0012608 name: KIF3C_HUMAN-Phosphothreonine585 def: "Protein KIF3C_HUMAN with the residue 585 substituted with Phosphothreonine" [UniProtKB:O14782] xref: UniProtKB:O14782 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0005598 ! KIF3C_HUMAN [Term] id: CCO:B0012609 name: KIFC1_HUMAN-Phosphoserine33 def: "Protein KIFC1_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:Q9BW19] xref: UniProtKB:Q9BW19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002105 ! KIFC1_HUMAN [Term] id: CCO:B0012610 name: KIFC1_HUMAN-Phosphoserine351 def: "Protein KIFC1_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q9BW19] xref: UniProtKB:Q9BW19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0002105 ! KIFC1_HUMAN [Term] id: CCO:B0012611 name: KITH_HUMAN-Phosphoserine13 def: "Protein KITH_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P04183] xref: UniProtKB:P04183 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006114 ! KITH_HUMAN [Term] id: CCO:B0012612 name: KITH_HUMAN-Phosphoserine231 def: "Protein KITH_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:P04183] xref: UniProtKB:P04183 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006114 ! KITH_HUMAN [Term] id: CCO:B0012613 name: KNTC1_HUMAN-Phosphoserine2098 def: "Protein KNTC1_HUMAN with the residue 2098 substituted with Phosphoserine" [UniProtKB:P50748] xref: UniProtKB:P50748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000396 ! kinetochore microtubule relationship: transformation_of CCO:B0001645 ! KNTC1_HUMAN [Term] id: CCO:B0012619 name: KPCA_HUMAN-Phosphoserine226 def: "Protein KPCA_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:P17252] xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012620 name: KPCA_HUMAN-Phosphoserine319 def: "Protein KPCA_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:P17252] xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012621 name: KPCA_HUMAN-Phosphothreonine494 def: "Protein KPCA_HUMAN with the residue 494 substituted with Phosphothreonine" [UniProtKB:P17252] comment: By similarity xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012622 name: KPCA_HUMAN-Phosphothreonine495 def: "Protein KPCA_HUMAN with the residue 495 substituted with Phosphothreonine" [UniProtKB:P17252] comment: By similarity xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012623 name: KPCA_HUMAN-Phosphothreonine497 def: "Protein KPCA_HUMAN with the residue 497 substituted with Phosphothreonine" [UniProtKB:P17252] xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012624 name: KPCA_HUMAN-Phosphothreonine501 def: "Protein KPCA_HUMAN with the residue 501 substituted with Phosphothreonine" [UniProtKB:P17252] xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012625 name: KPCA_HUMAN-Phosphothreonine631 def: "Protein KPCA_HUMAN with the residue 631 substituted with Phosphothreonine" [UniProtKB:P17252] comment: by autocatalysis; Potential xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012626 name: KPCA_HUMAN-Phosphothreonine638 def: "Protein KPCA_HUMAN with the residue 638 substituted with Phosphothreonine" [UniProtKB:P17252] comment: by autocatalysis; xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012627 name: KPCA_HUMAN-Phosphoserine657 def: "Protein KPCA_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:P17252] comment: By similarity xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001065 ! calcium-dependent protein kinase C activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012628 name: KPCA_HUMAN-Phosphotyrosine658 def: "Protein KPCA_HUMAN with the residue 658 substituted with Phosphotyrosine" [UniProtKB:P17252] xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0012629 name: KPCI_HUMAN-Phosphotyrosine256 def: "Protein KPCI_HUMAN with the residue 256 substituted with Phosphotyrosine" [UniProtKB:P41743] comment: by Src; xref: UniProtKB:P41743 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:B0012630 name: KPCI_HUMAN-Phosphotyrosine271 def: "Protein KPCI_HUMAN with the residue 271 substituted with Phosphotyrosine" [UniProtKB:P41743] comment: by Src; xref: UniProtKB:P41743 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:B0012631 name: KPCI_HUMAN-Phosphotyrosine325 def: "Protein KPCI_HUMAN with the residue 325 substituted with Phosphotyrosine" [UniProtKB:P41743] comment: by Src; xref: UniProtKB:P41743 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001067 ! atypical protein kinase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000017 ! polarisome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001896 ! apical part of cell relationship: transformation_of CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:B0012632 name: KPCI_HUMAN-Phosphothreonine403 def: "Protein KPCI_HUMAN with the residue 403 substituted with Phosphothreonine" [UniProtKB:P41743] xref: UniProtKB:P41743 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:B0012633 name: KPCI_HUMAN-Phosphothreonine555 def: "Protein KPCI_HUMAN with the residue 555 substituted with Phosphothreonine" [UniProtKB:P41743] xref: UniProtKB:P41743 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:B0012634 name: KPCZ_HUMAN-Phosphoserine223 def: "Protein KPCZ_HUMAN with the residue 223 substituted with Phosphoserine" [UniProtKB:Q05513] xref: UniProtKB:Q05513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:B0012635 name: KPCZ_HUMAN-Phosphothreonine410 def: "Protein KPCZ_HUMAN with the residue 410 substituted with Phosphothreonine" [UniProtKB:Q05513] comment: by PDPK1; xref: UniProtKB:Q05513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:B0012636 name: KPCZ_HUMAN-Phosphothreonine560 def: "Protein KPCZ_HUMAN with the residue 560 substituted with Phosphothreonine" [UniProtKB:Q05513] xref: UniProtKB:Q05513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001067 ! atypical protein kinase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:B0012637 name: KS6A4_HUMAN-Phosphoserine196 def: "Protein KS6A4_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:O75676] comment: By similarity xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012638 name: KS6A4_HUMAN-Phosphoserine343 def: "Protein KS6A4_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:O75676] comment: By similarity xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012639 name: KS6A4_HUMAN-Phosphoserine347 def: "Protein KS6A4_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:O75676] comment: By similarity xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012640 name: KS6A4_HUMAN-Phosphoserine360 def: "Protein KS6A4_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:O75676] comment: By similarity xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012641 name: KS6A4_HUMAN-Phosphothreonine568 def: "Protein KS6A4_HUMAN with the residue 568 substituted with Phosphothreonine" [UniProtKB:O75676] comment: By similarity xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012642 name: KS6A4_HUMAN-Phosphoserine681 def: "Protein KS6A4_HUMAN with the residue 681 substituted with Phosphoserine" [UniProtKB:O75676] xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012643 name: KS6A4_HUMAN-Phosphoserine682 def: "Protein KS6A4_HUMAN with the residue 682 substituted with Phosphoserine" [UniProtKB:O75676] xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001077 ! ribosomal protein S6 kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007329 ! mitogen-activated protein kinase p38 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012644 name: KS6A4_HUMAN-Phosphoserine737 def: "Protein KS6A4_HUMAN with the residue 737 substituted with Phosphoserine" [UniProtKB:O75676] comment: By similarity xref: UniProtKB:O75676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:B0012645 name: KS6B2_HUMAN-Phosphoserine15 def: "Protein KS6B2_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q9UBS0] xref: UniProtKB:Q9UBS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002193 ! KS6B2_HUMAN [Term] id: CCO:B0012646 name: KS6B2_HUMAN-Phosphoserine356 def: "Protein KS6B2_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:Q9UBS0] xref: UniProtKB:Q9UBS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0002193 ! KS6B2_HUMAN [Term] id: CCO:B0012647 name: KTNB1_HUMAN-Phosphothreonine395 def: "Protein KTNB1_HUMAN with the residue 395 substituted with Phosphothreonine" [UniProtKB:Q9BVA0] xref: UniProtKB:Q9BVA0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002100 ! KTNB1_HUMAN [Term] id: CCO:B0012648 name: KU70_HUMAN-N-acetylserine2 def: "Protein KU70_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P12956] comment: Potential xref: UniProtKB:P12956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:B0012649 name: KU70_HUMAN-Phosphoserine6 def: "Protein KU70_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:P12956] comment: by PRKDC; xref: UniProtKB:P12956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:B0012650 name: KU70_HUMAN-Phosphoserine27 def: "Protein KU70_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P12956] xref: UniProtKB:P12956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:B0012651 name: KU70_HUMAN-Phosphoserine51 def: "Protein KU70_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P12956] comment: by PRKDC; xref: UniProtKB:P12956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000506 ! DNA-dependent protein kinase complex relationship: transformation_of CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:B0012652 name: KU70_HUMAN-Phosphoserine222 def: "Protein KU70_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:P12956] xref: UniProtKB:P12956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:B0012653 name: KU86_HUMAN-Phosphoserine577 def: "Protein KU86_HUMAN with the residue 577 substituted with Phosphoserine" [UniProtKB:P13010] comment: by PRKDC; xref: UniProtKB:P13010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:B0012654 name: KU86_HUMAN-Phosphoserine579 def: "Protein KU86_HUMAN with the residue 579 substituted with Phosphoserine" [UniProtKB:P13010] comment: by PRKDC; Probable xref: UniProtKB:P13010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:B0012655 name: KU86_HUMAN-Phosphoserine580 def: "Protein KU86_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:P13010] comment: by PRKDC; xref: UniProtKB:P13010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:B0012656 name: KU86_HUMAN-Phosphothreonine715 def: "Protein KU86_HUMAN with the residue 715 substituted with Phosphothreonine" [UniProtKB:P13010] comment: by PRKDC; Probable xref: UniProtKB:P13010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:B0012657 name: L2GL2_HUMAN-Phosphoserine664 def: "Protein L2GL2_HUMAN with the residue 664 substituted with Phosphoserine" [UniProtKB:Q6P1M3] xref: UniProtKB:Q6P1M3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001913 ! L2GL2_HUMAN [Term] id: CCO:B0012658 name: LAMA4_HUMAN-Phosphotyrosine1593 def: "Protein LAMA4_HUMAN with the residue 1593 substituted with Phosphotyrosine" [UniProtKB:Q16363] xref: UniProtKB:Q16363 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000228 ! basal lamina relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: transformation_of CCO:B0006093 ! LAMA4_HUMAN [Term] id: CCO:B0012659 name: LAP2_HUMAN-Phosphoserine440 def: "Protein LAP2_HUMAN with the residue 440 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012660 name: LAP2_HUMAN-Phosphotyrosine483 def: "Protein LAP2_HUMAN with the residue 483 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012661 name: LAP2_HUMAN-Phosphothreonine485 def: "Protein LAP2_HUMAN with the residue 485 substituted with Phosphothreonine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012662 name: LAP2_HUMAN-Phosphotyrosine487 def: "Protein LAP2_HUMAN with the residue 487 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012663 name: LAP2_HUMAN-Phosphoserine598 def: "Protein LAP2_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012664 name: LAP2_HUMAN-Phosphoserine602 def: "Protein LAP2_HUMAN with the residue 602 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012665 name: LAP2_HUMAN-Phosphoserine603 def: "Protein LAP2_HUMAN with the residue 603 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012666 name: LAP2_HUMAN-Phosphotyrosine733 def: "Protein LAP2_HUMAN with the residue 733 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012667 name: LAP2_HUMAN-Phosphothreonine853 def: "Protein LAP2_HUMAN with the residue 853 substituted with Phosphothreonine" [UniProtKB:Q96RT1] comment: By similarity xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012668 name: LAP2_HUMAN-Phosphoserine857 def: "Protein LAP2_HUMAN with the residue 857 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012669 name: LAP2_HUMAN-Phosphothreonine917 def: "Protein LAP2_HUMAN with the residue 917 substituted with Phosphothreonine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012670 name: LAP2_HUMAN-Phosphotyrosine920 def: "Protein LAP2_HUMAN with the residue 920 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012671 name: LAP2_HUMAN-Phosphotyrosine972 def: "Protein LAP2_HUMAN with the residue 972 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012672 name: LAP2_HUMAN-Phosphotyrosine981 def: "Protein LAP2_HUMAN with the residue 981 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012673 name: LAP2_HUMAN-Phosphotyrosine1104 def: "Protein LAP2_HUMAN with the residue 1104 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012674 name: LAP2_HUMAN-Phosphotyrosine1107 def: "Protein LAP2_HUMAN with the residue 1107 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012675 name: LAP2_HUMAN-Phosphotyrosine1132 def: "Protein LAP2_HUMAN with the residue 1132 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012676 name: LAP2_HUMAN-Phosphoserine1271 def: "Protein LAP2_HUMAN with the residue 1271 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0012677 name: LATS1_HUMAN-Phosphoserine244 def: "Protein LATS1_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:O95835] xref: UniProtKB:O95835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001454 ! LATS1_HUMAN [Term] id: CCO:B0012678 name: LATS1_HUMAN-Phosphoserine464 def: "Protein LATS1_HUMAN with the residue 464 substituted with Phosphoserine" [UniProtKB:O95835] comment: By similarity xref: UniProtKB:O95835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001454 ! LATS1_HUMAN [Term] id: CCO:B0012679 name: LATS1_HUMAN-Phosphoserine674 def: "Protein LATS1_HUMAN with the residue 674 substituted with Phosphoserine" [UniProtKB:O95835] xref: UniProtKB:O95835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001454 ! LATS1_HUMAN [Term] id: CCO:B0012680 name: LATS1_HUMAN-Phosphoserine909 def: "Protein LATS1_HUMAN with the residue 909 substituted with Phosphoserine" [UniProtKB:O95835] comment: by STK3; xref: UniProtKB:O95835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0001454 ! LATS1_HUMAN [Term] id: CCO:B0012681 name: LATS1_HUMAN-Phosphothreonine1079 def: "Protein LATS1_HUMAN with the residue 1079 substituted with Phosphothreonine" [UniProtKB:O95835] comment: by STK3; xref: UniProtKB:O95835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001454 ! LATS1_HUMAN [Term] id: CCO:B0012682 name: LATS2_HUMAN-Phosphoserine83 def: "Protein LATS2_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q9NRM7] comment: by STK6; xref: UniProtKB:Q9NRM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002159 ! LATS2_HUMAN [Term] id: CCO:B0012683 name: LC7L2_HUMAN-Phosphothreonine17 def: "Protein LC7L2_HUMAN with the residue 17 substituted with Phosphothreonine" [UniProtKB:Q9Y383] xref: UniProtKB:Q9Y383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:B0012684 name: LC7L2_HUMAN-Phosphoserine18 def: "Protein LC7L2_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q9Y383] xref: UniProtKB:Q9Y383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:B0012685 name: LC7L2_HUMAN-Phosphothreonine111 def: "Protein LC7L2_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:Q9Y383] xref: UniProtKB:Q9Y383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:B0012686 name: LC7L2_HUMAN-Phosphoserine354 def: "Protein LC7L2_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q9Y383] xref: UniProtKB:Q9Y383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:B0012687 name: LC7L2_HUMAN-Phosphoserine358 def: "Protein LC7L2_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:Q9Y383] xref: UniProtKB:Q9Y383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:B0012688 name: LC7L2_HUMAN-Phosphoserine383 def: "Protein LC7L2_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q9Y383] xref: UniProtKB:Q9Y383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:B0012689 name: LC7L2_HUMAN-Phosphoserine384 def: "Protein LC7L2_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q9Y383] xref: UniProtKB:Q9Y383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:B0012690 name: LCK_HUMAN-Phosphoserine162 def: "Protein LCK_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:P06239] xref: UniProtKB:P06239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001490 ! LCK_HUMAN [Term] id: CCO:B0012691 name: LCK_HUMAN-Phosphotyrosine192 def: "Protein LCK_HUMAN with the residue 192 substituted with Phosphotyrosine" [UniProtKB:P06239] xref: UniProtKB:P06239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001490 ! LCK_HUMAN [Term] id: CCO:B0012692 name: LCK_HUMAN-Phosphoserine213 def: "Protein LCK_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:P06239] xref: UniProtKB:P06239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001490 ! LCK_HUMAN [Term] id: CCO:B0012693 name: LCK_HUMAN-Phosphotyrosine394 def: "Protein LCK_HUMAN with the residue 394 substituted with Phosphotyrosine" [UniProtKB:P06239] comment: by autocatalysis; xref: UniProtKB:P06239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001490 ! LCK_HUMAN [Term] id: CCO:B0012694 name: LCK_HUMAN-Phosphothreonine501 def: "Protein LCK_HUMAN with the residue 501 substituted with Phosphothreonine" [UniProtKB:P06239] xref: UniProtKB:P06239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001490 ! LCK_HUMAN [Term] id: CCO:B0012695 name: LCK_HUMAN-Phosphotyrosine505 def: "Protein LCK_HUMAN with the residue 505 substituted with Phosphotyrosine" [UniProtKB:P06239] xref: UniProtKB:P06239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001490 ! LCK_HUMAN [Term] id: CCO:B0012696 name: LEPR_HUMAN-Phosphotyrosine986 def: "Protein LEPR_HUMAN with the residue 986 substituted with Phosphotyrosine" [UniProtKB:P48357] comment: by JAK2; By similarity xref: UniProtKB:P48357 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005902 ! LEPR_HUMAN [Term] id: CCO:B0012697 name: LEPR_HUMAN-Phosphotyrosine1141 def: "Protein LEPR_HUMAN with the residue 1141 substituted with Phosphotyrosine" [UniProtKB:P48357] comment: by JAK2; By similarity xref: UniProtKB:P48357 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005902 ! LEPR_HUMAN [Term] id: CCO:B0012698 name: LIMK1_HUMAN-Phosphoserine298 def: "Protein LIMK1_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:P53667] xref: UniProtKB:P53667 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000477 ! focal adhesion relationship: transformation_of CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:B0012699 name: LIMK1_HUMAN-Phosphoserine310 def: "Protein LIMK1_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:P53667] xref: UniProtKB:P53667 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:B0012700 name: LIMK1_HUMAN-Phosphothreonine508 def: "Protein LIMK1_HUMAN with the residue 508 substituted with Phosphothreonine" [UniProtKB:P53667] comment: by ROCK1; xref: UniProtKB:P53667 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:B0012701 name: LIN9_HUMAN-Phosphoserine309 def: "Protein LIN9_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:Q5TKA1] xref: UniProtKB:Q5TKA1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001894 ! LIN9_HUMAN [Term] id: CCO:B0012702 name: LIPA2_HUMAN-Phosphoserine538 def: "Protein LIPA2_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:O75334] comment: By similarity xref: UniProtKB:O75334 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005602 ! LIPA2_HUMAN [Term] id: CCO:B0012703 name: LIPA2_HUMAN-Phosphoserine689 def: "Protein LIPA2_HUMAN with the residue 689 substituted with Phosphoserine" [UniProtKB:O75334] comment: By similarity xref: UniProtKB:O75334 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005602 ! LIPA2_HUMAN [Term] id: CCO:B0012704 name: LIPA2_HUMAN-Phosphoserine774 def: "Protein LIPA2_HUMAN with the residue 774 substituted with Phosphoserine" [UniProtKB:O75334] comment: By similarity xref: UniProtKB:O75334 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005602 ! LIPA2_HUMAN [Term] id: CCO:B0012705 name: LPP3_HUMAN-Phosphotyrosine110 def: "Protein LPP3_HUMAN with the residue 110 substituted with Phosphotyrosine" [UniProtKB:O14495] xref: UniProtKB:O14495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006019 ! LPP3_HUMAN [Term] id: CCO:B0012706 name: LSD1_HUMAN-Phosphoserine166 def: "Protein LSD1_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:O60341] xref: UniProtKB:O60341 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005589 ! LSD1_HUMAN [Term] id: CCO:B0012707 name: LSM3_HUMAN-N-acetylalanine2 def: "Protein LSM3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62310] xref: UniProtKB:P62310 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0005566 ! LSM3_HUMAN [Term] id: CCO:B0012708 name: LSM8_HUMAN-N-acetylthreonine2 def: "Protein LSM8_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:O95777] xref: UniProtKB:O95777 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005349 ! LSM8_HUMAN [Term] id: CCO:B0012709 name: LYN_HUMAN-Phosphoserine11 def: "Protein LYN_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P07948] xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0012710 name: LYN_HUMAN-Phosphoserine13 def: "Protein LYN_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P07948] xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0012711 name: LYN_HUMAN-Phosphotyrosine397 def: "Protein LYN_HUMAN with the residue 397 substituted with Phosphotyrosine" [UniProtKB:P07948] comment: by autocatalysis; By similarity xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0012712 name: LYN_HUMAN-Phosphotyrosine508 def: "Protein LYN_HUMAN with the residue 508 substituted with Phosphotyrosine" [UniProtKB:P07948] xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0012713 name: M1IP1_HUMAN-Phosphoserine75 def: "Protein M1IP1_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q9NPA3] comment: By similarity xref: UniProtKB:Q9NPA3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005281 ! M1IP1_HUMAN [Term] id: CCO:B0012714 name: M2OM_HUMAN-N-acetylalanine2 def: "Protein M2OM_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q02978] xref: UniProtKB:Q02978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002794 ! oxoglutarate:malate antiporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0006316 ! M2OM_HUMAN [Term] id: CCO:B0012715 name: M3K11_HUMAN-Phosphothreonine277 def: "Protein M3K11_HUMAN with the residue 277 substituted with Phosphothreonine" [UniProtKB:Q16584] comment: by autocatalysis; xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012716 name: M3K11_HUMAN-Phosphoserine281 def: "Protein M3K11_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q16584] comment: by autocatalysis and MAP4K1; xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012717 name: M3K11_HUMAN-Phosphoserine507 def: "Protein M3K11_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012718 name: M3K11_HUMAN-Phosphoserine524 def: "Protein M3K11_HUMAN with the residue 524 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012719 name: M3K11_HUMAN-Phosphoserine555 def: "Protein M3K11_HUMAN with the residue 555 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012720 name: M3K11_HUMAN-Phosphoserine556 def: "Protein M3K11_HUMAN with the residue 556 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012721 name: M3K11_HUMAN-Phosphoserine654 def: "Protein M3K11_HUMAN with the residue 654 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012722 name: M3K11_HUMAN-Phosphoserine705 def: "Protein M3K11_HUMAN with the residue 705 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012723 name: M3K11_HUMAN-Phosphoserine724 def: "Protein M3K11_HUMAN with the residue 724 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001072 ! JUN kinase kinase kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012724 name: M3K11_HUMAN-Phosphoserine727 def: "Protein M3K11_HUMAN with the residue 727 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012725 name: M3K11_HUMAN-Phosphothreonine738 def: "Protein M3K11_HUMAN with the residue 738 substituted with Phosphothreonine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012726 name: M3K11_HUMAN-Phosphoserine740 def: "Protein M3K11_HUMAN with the residue 740 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012727 name: M3K11_HUMAN-Phosphoserine746 def: "Protein M3K11_HUMAN with the residue 746 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012728 name: M3K11_HUMAN-Phosphoserine758 def: "Protein M3K11_HUMAN with the residue 758 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012729 name: M3K11_HUMAN-Phosphoserine770 def: "Protein M3K11_HUMAN with the residue 770 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012730 name: M3K11_HUMAN-Phosphoserine793 def: "Protein M3K11_HUMAN with the residue 793 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0012731 name: M3K1_HUMAN-Phosphothreonine1402 def: "Protein M3K1_HUMAN with the residue 1402 substituted with Phosphothreonine" [UniProtKB:Q13233] comment: by autocatalysis; By similarity xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0012732 name: M3K1_HUMAN-Phosphothreonine1414 def: "Protein M3K1_HUMAN with the residue 1414 substituted with Phosphothreonine" [UniProtKB:Q13233] comment: by autocatalysis; By similarity xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0012733 name: M3K3_HUMAN-Phosphotyrosine288 def: "Protein M3K3_HUMAN with the residue 288 substituted with Phosphotyrosine" [UniProtKB:Q99759] xref: UniProtKB:Q99759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:B0012734 name: M3K3_HUMAN-Phosphoserine289 def: "Protein M3K3_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q99759] xref: UniProtKB:Q99759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:B0012735 name: M3K3_HUMAN-Phosphothreonine294 def: "Protein M3K3_HUMAN with the residue 294 substituted with Phosphothreonine" [UniProtKB:Q99759] xref: UniProtKB:Q99759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:B0012736 name: M3K3_HUMAN-Phosphoserine337 def: "Protein M3K3_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q99759] comment: By similarity xref: UniProtKB:Q99759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:B0012737 name: M3K3_HUMAN-Phosphoserine340 def: "Protein M3K3_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q99759] comment: By similarity xref: UniProtKB:Q99759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:B0012738 name: M3K3_HUMAN-Phosphothreonine530 def: "Protein M3K3_HUMAN with the residue 530 substituted with Phosphothreonine" [UniProtKB:Q99759] comment: By similarity xref: UniProtKB:Q99759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:B0012739 name: M3K4_HUMAN-Phosphoserine499 def: "Protein M3K4_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:Q9Y6R4] comment: By similarity xref: UniProtKB:Q9Y6R4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005915 ! M3K4_HUMAN [Term] id: CCO:B0012740 name: M3K4_HUMAN-Phosphothreonine1504 def: "Protein M3K4_HUMAN with the residue 1504 substituted with Phosphothreonine" [UniProtKB:Q9Y6R4] comment: By similarity xref: UniProtKB:Q9Y6R4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005915 ! M3K4_HUMAN [Term] id: CCO:B0012741 name: M3K5_HUMAN-Phosphothreonine838 def: "Protein M3K5_HUMAN with the residue 838 substituted with Phosphothreonine" [UniProtKB:Q99683] xref: UniProtKB:Q99683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:B0012742 name: M3K5_HUMAN-Phosphoserine958 def: "Protein M3K5_HUMAN with the residue 958 substituted with Phosphoserine" [UniProtKB:Q99683] comment: By similarity xref: UniProtKB:Q99683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:B0012743 name: M3K5_HUMAN-Phosphoserine966 def: "Protein M3K5_HUMAN with the residue 966 substituted with Phosphoserine" [UniProtKB:Q99683] xref: UniProtKB:Q99683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:B0012744 name: M3K5_HUMAN-Phosphoserine1033 def: "Protein M3K5_HUMAN with the residue 1033 substituted with Phosphoserine" [UniProtKB:Q99683] xref: UniProtKB:Q99683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:B0012746 name: MACF1_HUMAN-Phosphoserine280 def: "Protein MACF1_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q9UPN3] comment: By similarity xref: UniProtKB:Q9UPN3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002237 ! MACF1_HUMAN [Term] id: CCO:B0012747 name: MACF1_HUMAN-Phosphoserine1860 def: "Protein MACF1_HUMAN with the residue 1860 substituted with Phosphoserine" [UniProtKB:Q9UPN3] xref: UniProtKB:Q9UPN3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0002237 ! MACF1_HUMAN [Term] id: CCO:B0012748 name: MACF1_HUMAN-Phosphoserine2454 def: "Protein MACF1_HUMAN with the residue 2454 substituted with Phosphoserine" [UniProtKB:Q9UPN3] xref: UniProtKB:Q9UPN3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002237 ! MACF1_HUMAN [Term] id: CCO:B0012749 name: MACF1_HUMAN-Phosphoserine4074 def: "Protein MACF1_HUMAN with the residue 4074 substituted with Phosphoserine" [UniProtKB:Q9UPN3] comment: By similarity xref: UniProtKB:Q9UPN3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002237 ! MACF1_HUMAN [Term] id: CCO:B0012750 name: MACF1_HUMAN-Phosphoserine5372 def: "Protein MACF1_HUMAN with the residue 5372 substituted with Phosphoserine" [UniProtKB:Q9UPN3] comment: By similarity xref: UniProtKB:Q9UPN3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002237 ! MACF1_HUMAN [Term] id: CCO:B0012751 name: MACF1_HUMAN-Phosphoserine5375 def: "Protein MACF1_HUMAN with the residue 5375 substituted with Phosphoserine" [UniProtKB:Q9UPN3] comment: By similarity xref: UniProtKB:Q9UPN3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002237 ! MACF1_HUMAN [Term] id: CCO:B0012752 name: MACF4_HUMAN-Phosphoserine2576 def: "Protein MACF4_HUMAN with the residue 2576 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0012753 name: MACF4_HUMAN-Phosphoserine2577 def: "Protein MACF4_HUMAN with the residue 2577 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0012754 name: MACF4_HUMAN-Phosphoserine2579 def: "Protein MACF4_HUMAN with the residue 2579 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0012755 name: MACF4_HUMAN-Phosphothreonine5627 def: "Protein MACF4_HUMAN with the residue 5627 substituted with Phosphothreonine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0012756 name: MACF4_HUMAN-Phosphothreonine5823 def: "Protein MACF4_HUMAN with the residue 5823 substituted with Phosphothreonine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0012757 name: MADD_HUMAN-Phosphoserine1059 def: "Protein MADD_HUMAN with the residue 1059 substituted with Phosphoserine" [UniProtKB:Q8WXG6] comment: By similarity xref: UniProtKB:Q8WXG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002010 ! MADD_HUMAN [Term] id: CCO:B0012758 name: MADD_HUMAN-Phosphothreonine1061 def: "Protein MADD_HUMAN with the residue 1061 substituted with Phosphothreonine" [UniProtKB:Q8WXG6] comment: By similarity xref: UniProtKB:Q8WXG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002010 ! MADD_HUMAN [Term] id: CCO:B0012759 name: MAF1_HUMAN-Phosphoserine75 def: "Protein MAF1_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q9H063] xref: UniProtKB:Q9H063 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005301 ! MAF1_HUMAN [Term] id: CCO:B0012760 name: MAGAB_HUMAN-Phosphoserine76 def: "Protein MAGAB_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:P43364] xref: UniProtKB:P43364 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005212 ! MAGAB_HUMAN [Term] id: CCO:B0012761 name: MAP9_HUMAN-Phosphoserine132 def: "Protein MAP9_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q49MG5] xref: UniProtKB:Q49MG5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0001834 ! MAP9_HUMAN [Term] id: CCO:B0012762 name: MAPK5_HUMAN-Phosphothreonine182 def: "Protein MAPK5_HUMAN with the residue 182 substituted with Phosphothreonine" [UniProtKB:Q8IW41] xref: UniProtKB:Q8IW41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005891 ! MAPK5_HUMAN [Term] id: CCO:B0012763 name: MARE1_HUMAN-N-acetylalanine2 def: "Protein MARE1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q15691] xref: UniProtKB:Q15691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0008033 ! microtubule plus-end binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001096 ! cortical microtubule cytoskeleton relationship: transformation_of CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:B0012764 name: MARE1_HUMAN-Phosphotyrosine124 def: "Protein MARE1_HUMAN with the residue 124 substituted with Phosphotyrosine" [UniProtKB:Q15691] xref: UniProtKB:Q15691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:B0012765 name: MARE1_HUMAN-Phosphoserine155 def: "Protein MARE1_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q15691] xref: UniProtKB:Q15691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:B0012766 name: MARE1_HUMAN-Phosphothreonine166 def: "Protein MARE1_HUMAN with the residue 166 substituted with Phosphothreonine" [UniProtKB:Q15691] xref: UniProtKB:Q15691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:B0012767 name: MARE2_HUMAN-Phosphotyrosine167 def: "Protein MARE2_HUMAN with the residue 167 substituted with Phosphotyrosine" [UniProtKB:Q15555] xref: UniProtKB:Q15555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001811 ! MARE2_HUMAN [Term] id: CCO:B0012768 name: MARE2_HUMAN-Phosphoserine200 def: "Protein MARE2_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q15555] xref: UniProtKB:Q15555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001811 ! MARE2_HUMAN [Term] id: CCO:B0012769 name: MARE2_HUMAN-Phosphoserine219 def: "Protein MARE2_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q15555] xref: UniProtKB:Q15555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001811 ! MARE2_HUMAN [Term] id: CCO:B0012770 name: MARE2_HUMAN-Phosphoserine223 def: "Protein MARE2_HUMAN with the residue 223 substituted with Phosphoserine" [UniProtKB:Q15555] xref: UniProtKB:Q15555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001811 ! MARE2_HUMAN [Term] id: CCO:B0012771 name: MARE3_HUMAN-Phosphothreonine161 def: "Protein MARE3_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:Q9UPY8] comment: By similarity xref: UniProtKB:Q9UPY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002238 ! MARE3_HUMAN [Term] id: CCO:B0012772 name: MARK3_HUMAN-Phosphothreonine234 def: "Protein MARK3_HUMAN with the residue 234 substituted with Phosphothreonine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0012773 name: MARK3_HUMAN-Phosphoserine442 def: "Protein MARK3_HUMAN with the residue 442 substituted with Phosphoserine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0012774 name: MARK3_HUMAN-Phosphoserine492 def: "Protein MARK3_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0012775 name: MARK3_HUMAN-Phosphoserine624 def: "Protein MARK3_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0012776 name: MARK4_HUMAN-Phosphoserine26 def: "Protein MARK4_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q96L34] xref: UniProtKB:Q96L34 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005782 ! gamma-tubulin binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_function CCO:F0007673 ! tau-protein kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: located_in CCO:C0001707 ! neuron projection relationship: transformation_of CCO:B0005344 ! MARK4_HUMAN [Term] id: CCO:B0012777 name: MARK4_HUMAN-Phosphothreonine214 def: "Protein MARK4_HUMAN with the residue 214 substituted with Phosphothreonine" [UniProtKB:Q96L34] xref: UniProtKB:Q96L34 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005344 ! MARK4_HUMAN [Term] id: CCO:B0012778 name: MAST3_HUMAN-Phosphoserine1223 def: "Protein MAST3_HUMAN with the residue 1223 substituted with Phosphoserine" [UniProtKB:O60307] comment: By similarity xref: UniProtKB:O60307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005499 ! MAST3_HUMAN [Term] id: CCO:B0012779 name: MAST3_HUMAN-Phosphoserine1273 def: "Protein MAST3_HUMAN with the residue 1273 substituted with Phosphoserine" [UniProtKB:O60307] comment: By similarity xref: UniProtKB:O60307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005499 ! MAST3_HUMAN [Term] id: CCO:B0012780 name: MATK_HUMAN-Phosphoserine501 def: "Protein MATK_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:P42679] xref: UniProtKB:P42679 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001612 ! MATK_HUMAN [Term] id: CCO:B0012781 name: MATK_HUMAN-Phosphoserine504 def: "Protein MATK_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:P42679] xref: UniProtKB:P42679 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001612 ! MATK_HUMAN [Term] id: CCO:B0012782 name: MATR3_HUMAN-Phosphoserine188 def: "Protein MATR3_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012783 name: MATR3_HUMAN-Phosphoserine195 def: "Protein MATR3_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012784 name: MATR3_HUMAN-Phosphoserine208 def: "Protein MATR3_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012785 name: MATR3_HUMAN-Phosphoserine397 def: "Protein MATR3_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012786 name: MATR3_HUMAN-Phosphoserine596 def: "Protein MATR3_HUMAN with the residue 596 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012787 name: MATR3_HUMAN-Phosphoserine598 def: "Protein MATR3_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012788 name: MATR3_HUMAN-Phosphoserine604 def: "Protein MATR3_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012789 name: MATR3_HUMAN-Phosphoserine654 def: "Protein MATR3_HUMAN with the residue 654 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012790 name: MATR3_HUMAN-Phosphoserine671 def: "Protein MATR3_HUMAN with the residue 671 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012791 name: MATR3_HUMAN-Phosphoserine673 def: "Protein MATR3_HUMAN with the residue 673 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012792 name: MATR3_HUMAN-Phosphoserine674 def: "Protein MATR3_HUMAN with the residue 674 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012793 name: MATR3_HUMAN-Phosphoserine696 def: "Protein MATR3_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0012794 name: MAX_HUMAN-Phosphoserine2 def: "Protein MAX_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P61244] xref: UniProtKB:P61244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:B0012795 name: MAX_HUMAN-Phosphoserine11 def: "Protein MAX_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P61244] xref: UniProtKB:P61244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:B0012796 name: MAX_HUMAN-N6-acetyllysine66 def: "Protein MAX_HUMAN with the residue 66 substituted with N6-acetyllysine" [UniProtKB:P61244] comment: Probable xref: UniProtKB:P61244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:B0012797 name: MAX_HUMAN-Phosphotyrosine123 def: "Protein MAX_HUMAN with the residue 123 substituted with Phosphotyrosine" [UniProtKB:P61244] xref: UniProtKB:P61244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:B0012798 name: MAX_HUMAN-N6-acetyllysine153 def: "Protein MAX_HUMAN with the residue 153 substituted with N6-acetyllysine" [UniProtKB:P61244] comment: alternate; xref: UniProtKB:P61244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:B0012799 name: MAX_HUMAN-N6-acetyllysine154 def: "Protein MAX_HUMAN with the residue 154 substituted with N6-acetyllysine" [UniProtKB:P61244] comment: alternate; xref: UniProtKB:P61244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:B0012800 name: MBD1_HUMAN-Phosphotyrosine52 def: "Protein MBD1_HUMAN with the residue 52 substituted with Phosphotyrosine" [UniProtKB:Q9UIS9] xref: UniProtKB:Q9UIS9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:B0012801 name: MBD1_HUMAN-Phosphoserine295 def: "Protein MBD1_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q9UIS9] xref: UniProtKB:Q9UIS9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001837 ! methyl-CpG binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:B0012802 name: MBD1_HUMAN-Phosphothreonine301 def: "Protein MBD1_HUMAN with the residue 301 substituted with Phosphothreonine" [UniProtKB:Q9UIS9] xref: UniProtKB:Q9UIS9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:B0012803 name: MCM10_HUMAN-Phosphothreonine85 def: "Protein MCM10_HUMAN with the residue 85 substituted with Phosphothreonine" [UniProtKB:Q7L590] xref: UniProtKB:Q7L590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:B0012804 name: MCM10_HUMAN-Phosphoserine93 def: "Protein MCM10_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q7L590] xref: UniProtKB:Q7L590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:B0012805 name: MCM2_HUMAN-Phosphoserine13 def: "Protein MCM2_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012806 name: MCM2_HUMAN-Phosphoserine26 def: "Protein MCM2_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012807 name: MCM2_HUMAN-Phosphoserine27 def: "Protein MCM2_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000280 ! DNA replication origin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000269 ! nuclear origin of replication recognition complex relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012808 name: MCM2_HUMAN-Phosphothreonine39 def: "Protein MCM2_HUMAN with the residue 39 substituted with Phosphothreonine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012809 name: MCM2_HUMAN-Phosphoserine40 def: "Protein MCM2_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:P49736] comment: by CDC7; xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012810 name: MCM2_HUMAN-Phosphoserine41 def: "Protein MCM2_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012811 name: MCM2_HUMAN-Phosphothreonine106 def: "Protein MCM2_HUMAN with the residue 106 substituted with Phosphothreonine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012812 name: MCM2_HUMAN-Phosphoserine108 def: "Protein MCM2_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:P49736] comment: by ATR; xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012813 name: MCM2_HUMAN-Phosphoserine139 def: "Protein MCM2_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0012814 name: MCM3_HUMAN-N-acetylalanine2 def: "Protein MCM3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000266 ! alpha DNA polymerase:primase complex relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012815 name: MCM3_HUMAN-Phosphoserine535 def: "Protein MCM3_HUMAN with the residue 535 substituted with Phosphoserine" [UniProtKB:P25205] comment: by ATM; xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012816 name: MCM3_HUMAN-Phosphoserine668 def: "Protein MCM3_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:P25205] comment: By similarity xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012817 name: MCM3_HUMAN-Phosphoserine672 def: "Protein MCM3_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012818 name: MCM3_HUMAN-Phosphothreonine674 def: "Protein MCM3_HUMAN with the residue 674 substituted with Phosphothreonine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012819 name: MCM3_HUMAN-Phosphoserine681 def: "Protein MCM3_HUMAN with the residue 681 substituted with Phosphoserine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012820 name: MCM3_HUMAN-Phosphoserine704 def: "Protein MCM3_HUMAN with the residue 704 substituted with Phosphoserine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012821 name: MCM3_HUMAN-Phosphoserine711 def: "Protein MCM3_HUMAN with the residue 711 substituted with Phosphoserine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012822 name: MCM3_HUMAN-Phosphothreonine713 def: "Protein MCM3_HUMAN with the residue 713 substituted with Phosphothreonine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012823 name: MCM3_HUMAN-Phosphothreonine722 def: "Protein MCM3_HUMAN with the residue 722 substituted with Phosphothreonine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012824 name: MCM3_HUMAN-Phosphoserine728 def: "Protein MCM3_HUMAN with the residue 728 substituted with Phosphoserine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012825 name: MCM3_HUMAN-Phosphoserine734 def: "Protein MCM3_HUMAN with the residue 734 substituted with Phosphoserine" [UniProtKB:P25205] xref: UniProtKB:P25205 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:B0012826 name: MCM4_HUMAN-Phosphothreonine19 def: "Protein MCM4_HUMAN with the residue 19 substituted with Phosphothreonine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012827 name: MCM4_HUMAN-Phosphoserine26 def: "Protein MCM4_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012828 name: MCM4_HUMAN-Phosphoserine32 def: "Protein MCM4_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012829 name: MCM4_HUMAN-Phosphoserine105 def: "Protein MCM4_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012830 name: MCM4_HUMAN-Phosphothreonine110 def: "Protein MCM4_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012831 name: MCM4_HUMAN-Phosphoserine120 def: "Protein MCM4_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012832 name: MCM4_HUMAN-Phosphoserine131 def: "Protein MCM4_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012833 name: MCM4_HUMAN-Phosphoserine142 def: "Protein MCM4_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012834 name: MCM4_HUMAN-Phosphoserine145 def: "Protein MCM4_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012835 name: MCM4_HUMAN-Phosphoserine326 def: "Protein MCM4_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0012836 name: MCM6_HUMAN-Phosphoserine271 def: "Protein MCM6_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q14566] xref: UniProtKB:Q14566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:B0012837 name: MCM6_HUMAN-Phosphoserine762 def: "Protein MCM6_HUMAN with the residue 762 substituted with Phosphoserine" [UniProtKB:Q14566] xref: UniProtKB:Q14566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:B0012838 name: MCM6_HUMAN-Phosphothreonine791 def: "Protein MCM6_HUMAN with the residue 791 substituted with Phosphothreonine" [UniProtKB:Q14566] xref: UniProtKB:Q14566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:B0012839 name: MCM7_HUMAN-Phosphoserine549 def: "Protein MCM7_HUMAN with the residue 549 substituted with Phosphoserine" [UniProtKB:P33993] xref: UniProtKB:P33993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001589 ! MCM7_HUMAN [Term] id: CCO:B0012840 name: MCRS1_HUMAN-Phosphothreonine103 def: "Protein MCRS1_HUMAN with the residue 103 substituted with Phosphothreonine" [UniProtKB:Q96EZ8] xref: UniProtKB:Q96EZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002036 ! MCRS1_HUMAN [Term] id: CCO:B0012841 name: MCRS1_HUMAN-Phosphoserine108 def: "Protein MCRS1_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q96EZ8] xref: UniProtKB:Q96EZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002036 ! MCRS1_HUMAN [Term] id: CCO:B0012842 name: MCRS1_HUMAN-Phosphoserine282 def: "Protein MCRS1_HUMAN with the residue 282 substituted with Phosphoserine" [UniProtKB:Q96EZ8] xref: UniProtKB:Q96EZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002036 ! MCRS1_HUMAN [Term] id: CCO:B0012843 name: MD13L_HUMAN-Phosphoserine1643 def: "Protein MD13L_HUMAN with the residue 1643 substituted with Phosphoserine" [UniProtKB:Q71F56] xref: UniProtKB:Q71F56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005801 ! MD13L_HUMAN [Term] id: CCO:B0012844 name: MD1L1_HUMAN-Phosphoserine214 def: "Protein MD1L1_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q9Y6D9] xref: UniProtKB:Q9Y6D9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0002264 ! MD1L1_HUMAN [Term] id: CCO:B0012845 name: MD1L1_HUMAN-Phosphoserine428 def: "Protein MD1L1_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q9Y6D9] xref: UniProtKB:Q9Y6D9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002264 ! MD1L1_HUMAN [Term] id: CCO:B0012846 name: MD2BP_HUMAN-Phosphoserine29 def: "Protein MD2BP_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q15013] xref: UniProtKB:Q15013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001799 ! MD2BP_HUMAN [Term] id: CCO:B0012847 name: MD2BP_HUMAN-Phosphothreonine39 def: "Protein MD2BP_HUMAN with the residue 39 substituted with Phosphothreonine" [UniProtKB:Q15013] xref: UniProtKB:Q15013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001799 ! MD2BP_HUMAN [Term] id: CCO:B0012848 name: MDC1_HUMAN-Phosphoserine168 def: "Protein MDC1_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012849 name: MDC1_HUMAN-Phosphoserine329 def: "Protein MDC1_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012850 name: MDC1_HUMAN-Phosphothreonine331 def: "Protein MDC1_HUMAN with the residue 331 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012851 name: MDC1_HUMAN-Phosphoserine372 def: "Protein MDC1_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012852 name: MDC1_HUMAN-Phosphoserine376 def: "Protein MDC1_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012853 name: MDC1_HUMAN-Phosphothreonine378 def: "Protein MDC1_HUMAN with the residue 378 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012854 name: MDC1_HUMAN-Phosphoserine402 def: "Protein MDC1_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012855 name: MDC1_HUMAN-Phosphothreonine404 def: "Protein MDC1_HUMAN with the residue 404 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012856 name: MDC1_HUMAN-Phosphoserine422 def: "Protein MDC1_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012857 name: MDC1_HUMAN-Phosphoserine453 def: "Protein MDC1_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012858 name: MDC1_HUMAN-Phosphothreonine455 def: "Protein MDC1_HUMAN with the residue 455 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012859 name: MDC1_HUMAN-Phosphoserine495 def: "Protein MDC1_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012860 name: MDC1_HUMAN-Phosphoserine498 def: "Protein MDC1_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012861 name: MDC1_HUMAN-Phosphoserine513 def: "Protein MDC1_HUMAN with the residue 513 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012862 name: MDC1_HUMAN-Phosphoserine516 def: "Protein MDC1_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012863 name: MDC1_HUMAN-Phosphothreonine523 def: "Protein MDC1_HUMAN with the residue 523 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000815 ! flotillin complex relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012864 name: MDC1_HUMAN-Phosphothreonine652 def: "Protein MDC1_HUMAN with the residue 652 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012865 name: MDC1_HUMAN-Phosphothreonine659 def: "Protein MDC1_HUMAN with the residue 659 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012866 name: MDC1_HUMAN-Phosphoserine763 def: "Protein MDC1_HUMAN with the residue 763 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012867 name: MDC1_HUMAN-Phosphothreonine765 def: "Protein MDC1_HUMAN with the residue 765 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012868 name: MDC1_HUMAN-Phosphoserine780 def: "Protein MDC1_HUMAN with the residue 780 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012869 name: MDC1_HUMAN-Phosphoserine882 def: "Protein MDC1_HUMAN with the residue 882 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012870 name: MDC1_HUMAN-Phosphoserine955 def: "Protein MDC1_HUMAN with the residue 955 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012871 name: MDC1_HUMAN-Phosphoserine964 def: "Protein MDC1_HUMAN with the residue 964 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012872 name: MDC1_HUMAN-Phosphoserine986 def: "Protein MDC1_HUMAN with the residue 986 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012873 name: MDC1_HUMAN-Phosphoserine988 def: "Protein MDC1_HUMAN with the residue 988 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012874 name: MDC1_HUMAN-Phosphoserine995 def: "Protein MDC1_HUMAN with the residue 995 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012875 name: MDC1_HUMAN-Phosphoserine1068 def: "Protein MDC1_HUMAN with the residue 1068 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012876 name: MDC1_HUMAN-Phosphoserine1086 def: "Protein MDC1_HUMAN with the residue 1086 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012877 name: MDC1_HUMAN-Phosphoserine1095 def: "Protein MDC1_HUMAN with the residue 1095 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012878 name: MDC1_HUMAN-Phosphothreonine1425 def: "Protein MDC1_HUMAN with the residue 1425 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012879 name: MDC1_HUMAN-Phosphoserine1430 def: "Protein MDC1_HUMAN with the residue 1430 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012880 name: MDC1_HUMAN-Phosphothreonine1461 def: "Protein MDC1_HUMAN with the residue 1461 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012881 name: MDC1_HUMAN-Phosphothreonine1623 def: "Protein MDC1_HUMAN with the residue 1623 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012882 name: MDC1_HUMAN-Phosphoserine1797 def: "Protein MDC1_HUMAN with the residue 1797 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012883 name: MDC1_HUMAN-Phosphoserine1814 def: "Protein MDC1_HUMAN with the residue 1814 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012884 name: MDC1_HUMAN-Phosphoserine1820 def: "Protein MDC1_HUMAN with the residue 1820 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0012886 name: MED13_HUMAN-Phosphoserine890 def: "Protein MED13_HUMAN with the residue 890 substituted with Phosphoserine" [UniProtKB:Q9UHV7] xref: UniProtKB:Q9UHV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005794 ! MED13_HUMAN [Term] id: CCO:B0012887 name: MED13_HUMAN-Phosphoserine1029 def: "Protein MED13_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q9UHV7] xref: UniProtKB:Q9UHV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005794 ! MED13_HUMAN [Term] id: CCO:B0012888 name: MED14_HUMAN-Phosphoserine986 def: "Protein MED14_HUMAN with the residue 986 substituted with Phosphoserine" [UniProtKB:O60244] xref: UniProtKB:O60244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005800 ! MED14_HUMAN [Term] id: CCO:B0012889 name: MED14_HUMAN-Phosphoserine1128 def: "Protein MED14_HUMAN with the residue 1128 substituted with Phosphoserine" [UniProtKB:O60244] xref: UniProtKB:O60244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005800 ! MED14_HUMAN [Term] id: CCO:B0012890 name: MED17_HUMAN-Phosphoserine37 def: "Protein MED17_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q9NVC6] xref: UniProtKB:Q9NVC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: transformation_of CCO:B0005785 ! MED17_HUMAN [Term] id: CCO:B0012891 name: MED17_HUMAN-Phosphoserine185 def: "Protein MED17_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:Q9NVC6] xref: UniProtKB:Q9NVC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005785 ! MED17_HUMAN [Term] id: CCO:B0012892 name: MED18_HUMAN-Phosphoserine66 def: "Protein MED18_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q9BUE0] xref: UniProtKB:Q9BUE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005787 ! MED18_HUMAN [Term] id: CCO:B0012893 name: MED1_HUMAN-Phosphoserine18 def: "Protein MED1_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012894 name: MED1_HUMAN-Phosphoserine770 def: "Protein MED1_HUMAN with the residue 770 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012895 name: MED1_HUMAN-Phosphoserine771 def: "Protein MED1_HUMAN with the residue 771 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012896 name: MED1_HUMAN-Phosphoserine772 def: "Protein MED1_HUMAN with the residue 772 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012897 name: MED1_HUMAN-Phosphoserine774 def: "Protein MED1_HUMAN with the residue 774 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012898 name: MED1_HUMAN-Phosphoserine795 def: "Protein MED1_HUMAN with the residue 795 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012899 name: MED1_HUMAN-Phosphothreonine805 def: "Protein MED1_HUMAN with the residue 805 substituted with Phosphothreonine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012900 name: MED1_HUMAN-Phosphoserine953 def: "Protein MED1_HUMAN with the residue 953 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012901 name: MED1_HUMAN-Phosphothreonine1032 def: "Protein MED1_HUMAN with the residue 1032 substituted with Phosphothreonine" [UniProtKB:Q15648] comment: by MAPK1 or MAPK3; xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012902 name: MED1_HUMAN-Phosphothreonine1051 def: "Protein MED1_HUMAN with the residue 1051 substituted with Phosphothreonine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012903 name: MED1_HUMAN-Phosphothreonine1057 def: "Protein MED1_HUMAN with the residue 1057 substituted with Phosphothreonine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012904 name: MED1_HUMAN-Phosphoserine1134 def: "Protein MED1_HUMAN with the residue 1134 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012905 name: MED1_HUMAN-Phosphothreonine1457 def: "Protein MED1_HUMAN with the residue 1457 substituted with Phosphothreonine" [UniProtKB:Q15648] comment: by MAPK1 or MAPK3; xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0012906 name: MED24_HUMAN-Phosphoserine862 def: "Protein MED24_HUMAN with the residue 862 substituted with Phosphoserine" [UniProtKB:O75448] xref: UniProtKB:O75448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005799 ! MED24_HUMAN [Term] id: CCO:B0012907 name: MED24_HUMAN-Phosphoserine873 def: "Protein MED24_HUMAN with the residue 873 substituted with Phosphoserine" [UniProtKB:O75448] xref: UniProtKB:O75448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005799 ! MED24_HUMAN [Term] id: CCO:B0012908 name: MED26_HUMAN-Phosphoserine337 def: "Protein MED26_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:O95402] xref: UniProtKB:O95402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005575 ! MED26_HUMAN [Term] id: CCO:B0012909 name: MED26_HUMAN-Phosphoserine447 def: "Protein MED26_HUMAN with the residue 447 substituted with Phosphoserine" [UniProtKB:O95402] xref: UniProtKB:O95402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005575 ! MED26_HUMAN [Term] id: CCO:B0012910 name: MERL_HUMAN-Phosphoserine518 def: "Protein MERL_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:P35240] xref: UniProtKB:P35240 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001592 ! MERL_HUMAN [Term] id: CCO:B0012911 name: MET_HUMAN-Phosphothreonine977 def: "Protein MET_HUMAN with the residue 977 substituted with Phosphothreonine" [UniProtKB:P08581] xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0012912 name: MET_HUMAN-Phosphoserine988 def: "Protein MET_HUMAN with the residue 988 substituted with Phosphoserine" [UniProtKB:P08581] xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0012913 name: MET_HUMAN-Phosphoserine990 def: "Protein MET_HUMAN with the residue 990 substituted with Phosphoserine" [UniProtKB:P08581] xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0012914 name: MET_HUMAN-Phosphotyrosine1003 def: "Protein MET_HUMAN with the residue 1003 substituted with Phosphotyrosine" [UniProtKB:P08581] xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0012915 name: MET_HUMAN-Phosphotyrosine1235 def: "Protein MET_HUMAN with the residue 1235 substituted with Phosphotyrosine" [UniProtKB:P08581] comment: by autocatalysis; xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0012916 name: MET_HUMAN-Phosphotyrosine1356 def: "Protein MET_HUMAN with the residue 1356 substituted with Phosphotyrosine" [UniProtKB:P08581] xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001345 ! hepatocyte growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000896 ! flagellum relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0012917 name: MINT_HUMAN-Phosphoserine260 def: "Protein MINT_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012918 name: MINT_HUMAN-Phosphoserine263 def: "Protein MINT_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012919 name: MINT_HUMAN-Phosphothreonine266 def: "Protein MINT_HUMAN with the residue 266 substituted with Phosphothreonine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012920 name: MINT_HUMAN-Phosphoserine725 def: "Protein MINT_HUMAN with the residue 725 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012921 name: MINT_HUMAN-Phosphoserine727 def: "Protein MINT_HUMAN with the residue 727 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012922 name: MINT_HUMAN-Phosphoserine736 def: "Protein MINT_HUMAN with the residue 736 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012923 name: MINT_HUMAN-Phosphoserine740 def: "Protein MINT_HUMAN with the residue 740 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012924 name: MINT_HUMAN-Phosphoserine1261 def: "Protein MINT_HUMAN with the residue 1261 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012925 name: MINT_HUMAN-Phosphoserine1268 def: "Protein MINT_HUMAN with the residue 1268 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012926 name: MINT_HUMAN-Phosphoserine1278 def: "Protein MINT_HUMAN with the residue 1278 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012927 name: MINT_HUMAN-Phosphoserine1283 def: "Protein MINT_HUMAN with the residue 1283 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012928 name: MINT_HUMAN-Phosphoserine1380 def: "Protein MINT_HUMAN with the residue 1380 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012929 name: MINT_HUMAN-Phosphoserine1382 def: "Protein MINT_HUMAN with the residue 1382 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012930 name: MINT_HUMAN-Phosphothreonine1619 def: "Protein MINT_HUMAN with the residue 1619 substituted with Phosphothreonine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012931 name: MINT_HUMAN-Phosphoserine1797 def: "Protein MINT_HUMAN with the residue 1797 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012932 name: MINT_HUMAN-Phosphoserine1857 def: "Protein MINT_HUMAN with the residue 1857 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012933 name: MINT_HUMAN-Phosphoserine2101 def: "Protein MINT_HUMAN with the residue 2101 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012934 name: MINT_HUMAN-Phosphoserine2120 def: "Protein MINT_HUMAN with the residue 2120 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012935 name: MINT_HUMAN-Phosphoserine2126 def: "Protein MINT_HUMAN with the residue 2126 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012936 name: MINT_HUMAN-Phosphothreonine2393 def: "Protein MINT_HUMAN with the residue 2393 substituted with Phosphothreonine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0012937 name: MK01_HUMAN-N-acetylalanine2 def: "Protein MK01_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P28482] xref: UniProtKB:P28482 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001565 ! MK01_HUMAN [Term] id: CCO:B0012938 name: MK01_HUMAN-Phosphothreonine185 def: "Protein MK01_HUMAN with the residue 185 substituted with Phosphothreonine" [UniProtKB:P28482] xref: UniProtKB:P28482 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001565 ! MK01_HUMAN [Term] id: CCO:B0012939 name: MK01_HUMAN-Phosphotyrosine187 def: "Protein MK01_HUMAN with the residue 187 substituted with Phosphotyrosine" [UniProtKB:P28482] xref: UniProtKB:P28482 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001565 ! MK01_HUMAN [Term] id: CCO:B0012940 name: MK01_HUMAN-Phosphothreonine190 def: "Protein MK01_HUMAN with the residue 190 substituted with Phosphothreonine" [UniProtKB:P28482] comment: By similarity xref: UniProtKB:P28482 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001565 ! MK01_HUMAN [Term] id: CCO:B0012941 name: MK03_HUMAN-N-acetylalanine2 def: "Protein MK03_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P27361] xref: UniProtKB:P27361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001560 ! MK03_HUMAN [Term] id: CCO:B0012942 name: MK03_HUMAN-Phosphothreonine202 def: "Protein MK03_HUMAN with the residue 202 substituted with Phosphothreonine" [UniProtKB:P27361] xref: UniProtKB:P27361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001560 ! MK03_HUMAN [Term] id: CCO:B0012943 name: MK03_HUMAN-Phosphotyrosine204 def: "Protein MK03_HUMAN with the residue 204 substituted with Phosphotyrosine" [UniProtKB:P27361] xref: UniProtKB:P27361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001560 ! MK03_HUMAN [Term] id: CCO:B0012944 name: MK06_HUMAN-Phosphothreonine626 def: "Protein MK06_HUMAN with the residue 626 substituted with Phosphothreonine" [UniProtKB:Q16659] comment: By similarity xref: UniProtKB:Q16659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001822 ! MK06_HUMAN [Term] id: CCO:B0012945 name: MK06_HUMAN-Phosphotyrosine628 def: "Protein MK06_HUMAN with the residue 628 substituted with Phosphotyrosine" [UniProtKB:Q16659] comment: By similarity xref: UniProtKB:Q16659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001822 ! MK06_HUMAN [Term] id: CCO:B0012946 name: MK08_HUMAN-Phosphothreonine183 def: "Protein MK08_HUMAN with the residue 183 substituted with Phosphothreonine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012947 name: MK08_HUMAN-Phosphotyrosine185 def: "Protein MK08_HUMAN with the residue 185 substituted with Phosphotyrosine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012948 name: MK08_HUMAN-Phosphothreonine255 def: "Protein MK08_HUMAN with the residue 255 substituted with Phosphothreonine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012949 name: MK08_HUMAN-Phosphothreonine258 def: "Protein MK08_HUMAN with the residue 258 substituted with Phosphothreonine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012950 name: MK08_HUMAN-Phosphotyrosine259 def: "Protein MK08_HUMAN with the residue 259 substituted with Phosphotyrosine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012951 name: MK08_HUMAN-Phosphotyrosine357 def: "Protein MK08_HUMAN with the residue 357 substituted with Phosphotyrosine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012952 name: MK08_HUMAN-Phosphothreonine367 def: "Protein MK08_HUMAN with the residue 367 substituted with Phosphothreonine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012953 name: MK08_HUMAN-Phosphoserine377 def: "Protein MK08_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:P45983] xref: UniProtKB:P45983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001071 ! JUN kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:B0012954 name: MK11_HUMAN-Phosphothreonine180 def: "Protein MK11_HUMAN with the residue 180 substituted with Phosphothreonine" [UniProtKB:Q15759] comment: Probable xref: UniProtKB:Q15759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005892 ! MK11_HUMAN [Term] id: CCO:B0012955 name: MK11_HUMAN-Phosphotyrosine182 def: "Protein MK11_HUMAN with the residue 182 substituted with Phosphotyrosine" [UniProtKB:Q15759] xref: UniProtKB:Q15759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005892 ! MK11_HUMAN [Term] id: CCO:B0012956 name: MK12_HUMAN-Phosphotyrosine27 def: "Protein MK12_HUMAN with the residue 27 substituted with Phosphotyrosine" [UniProtKB:P53778] xref: UniProtKB:P53778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0001665 ! MK12_HUMAN [Term] id: CCO:B0012957 name: MK12_HUMAN-Phosphothreonine183 def: "Protein MK12_HUMAN with the residue 183 substituted with Phosphothreonine" [UniProtKB:P53778] comment: By similarity xref: UniProtKB:P53778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001665 ! MK12_HUMAN [Term] id: CCO:B0012958 name: MK12_HUMAN-Phosphotyrosine185 def: "Protein MK12_HUMAN with the residue 185 substituted with Phosphotyrosine" [UniProtKB:P53778] xref: UniProtKB:P53778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001665 ! MK12_HUMAN [Term] id: CCO:B0012959 name: MK13_HUMAN-Phosphothreonine180 def: "Protein MK13_HUMAN with the residue 180 substituted with Phosphothreonine" [UniProtKB:O15264] xref: UniProtKB:O15264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001844 ! MP kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001369 ! MK13_HUMAN [Term] id: CCO:B0012960 name: MK13_HUMAN-Phosphotyrosine182 def: "Protein MK13_HUMAN with the residue 182 substituted with Phosphotyrosine" [UniProtKB:O15264] xref: UniProtKB:O15264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001369 ! MK13_HUMAN [Term] id: CCO:B0012964 name: MLTK_HUMAN-Phosphothreonine161 def: "Protein MLTK_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:Q9NYL2] comment: by autocatalysis; xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0012965 name: MLTK_HUMAN-Phosphoserine165 def: "Protein MLTK_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q9NYL2] comment: by autocatalysis; xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0012966 name: MLTK_HUMAN-Phosphoserine635 def: "Protein MLTK_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:Q9NYL2] comment: By similarity xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0012967 name: MLTK_HUMAN-Phosphoserine637 def: "Protein MLTK_HUMAN with the residue 637 substituted with Phosphoserine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0012968 name: MLTK_HUMAN-Phosphothreonine639 def: "Protein MLTK_HUMAN with the residue 639 substituted with Phosphothreonine" [UniProtKB:Q9NYL2] comment: By similarity xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0012969 name: MON1A_HUMAN-Phosphoserine56 def: "Protein MON1A_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:Q86VX9] comment: By similarity xref: UniProtKB:Q86VX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005970 ! MON1A_HUMAN [Term] id: CCO:B0012970 name: MON1A_HUMAN-Phosphotyrosine57 def: "Protein MON1A_HUMAN with the residue 57 substituted with Phosphotyrosine" [UniProtKB:Q86VX9] comment: By similarity xref: UniProtKB:Q86VX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005970 ! MON1A_HUMAN [Term] id: CCO:B0012971 name: MON1A_HUMAN-Phosphoserine69 def: "Protein MON1A_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:Q86VX9] comment: By similarity xref: UniProtKB:Q86VX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005970 ! MON1A_HUMAN [Term] id: CCO:B0012972 name: MON1A_HUMAN-Phosphoserine72 def: "Protein MON1A_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:Q86VX9] comment: By similarity xref: UniProtKB:Q86VX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005970 ! MON1A_HUMAN [Term] id: CCO:B0012973 name: MORN_HUMAN-Pyrrolidone carboxylic acid1 def: "Protein MORN_HUMAN with the residue 1 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P69208] xref: UniProtKB:P69208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001698 ! MORN_HUMAN [Term] id: CCO:B0012974 name: MP2K1_HUMAN-Phosphoserine218 def: "Protein MP2K1_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q02750] comment: by RAF; xref: UniProtKB:Q02750 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001718 ! MP2K1_HUMAN [Term] id: CCO:B0012975 name: MP2K1_HUMAN-Phosphoserine222 def: "Protein MP2K1_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q02750] comment: by RAF; xref: UniProtKB:Q02750 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001718 ! MP2K1_HUMAN [Term] id: CCO:B0012976 name: MP2K6_HUMAN-O-acetylserine207 def: "Protein MP2K6_HUMAN with the residue 207 substituted with O-acetylserine" [UniProtKB:P52564] comment: by Yersinia yopJ; alternate; xref: UniProtKB:P52564 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001658 ! MP2K6_HUMAN [Term] id: CCO:B0012977 name: MP2K6_HUMAN-Phosphoserine207 def: "Protein MP2K6_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:P52564] comment: alternate; xref: UniProtKB:P52564 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001658 ! MP2K6_HUMAN [Term] id: CCO:B0012978 name: MP2K6_HUMAN-O-acetylthreonine211 def: "Protein MP2K6_HUMAN with the residue 211 substituted with O-acetylthreonine" [UniProtKB:P52564] comment: by Yersinia yopJ; alternate; xref: UniProtKB:P52564 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001658 ! MP2K6_HUMAN [Term] id: CCO:B0012979 name: MP2K6_HUMAN-Phosphothreonine211 def: "Protein MP2K6_HUMAN with the residue 211 substituted with Phosphothreonine" [UniProtKB:P52564] comment: alternate; xref: UniProtKB:P52564 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001658 ! MP2K6_HUMAN [Term] id: CCO:B0012980 name: MPCP_HUMAN-N6-acetyllysine99 def: "Protein MPCP_HUMAN with the residue 99 substituted with N6-acetyllysine" [UniProtKB:Q00325] comment: By similarity xref: UniProtKB:Q00325 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002742 ! symporter activity relationship: has_function CCO:F0002765 ! phosphate carrier activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005847 ! MPCP_HUMAN [Term] id: CCO:B0012981 name: MPCP_HUMAN-N6-acetyllysine209 def: "Protein MPCP_HUMAN with the residue 209 substituted with N6-acetyllysine" [UniProtKB:Q00325] comment: By similarity xref: UniProtKB:Q00325 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005847 ! MPCP_HUMAN [Term] id: CCO:B0012982 name: MPH6_HUMAN-Phosphothreonine147 def: "Protein MPH6_HUMAN with the residue 147 substituted with Phosphothreonine" [UniProtKB:Q99547] xref: UniProtKB:Q99547 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002071 ! MPH6_HUMAN [Term] id: CCO:B0012983 name: MPIP1_HUMAN-Phosphoserine76 def: "Protein MPIP1_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:P30304] comment: by CHK1; xref: UniProtKB:P30304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001576 ! MPIP1_HUMAN [Term] id: CCO:B0012984 name: MPIP1_HUMAN-Phosphoserine124 def: "Protein MPIP1_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:P30304] comment: by CHK1 and CHK2; xref: UniProtKB:P30304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001576 ! MPIP1_HUMAN [Term] id: CCO:B0012985 name: MPIP1_HUMAN-Phosphoserine178 def: "Protein MPIP1_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:P30304] comment: by CHK1; xref: UniProtKB:P30304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001576 ! MPIP1_HUMAN [Term] id: CCO:B0012986 name: MPIP1_HUMAN-Phosphoserine279 def: "Protein MPIP1_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:P30304] comment: by CHK1 and CHK2; xref: UniProtKB:P30304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001576 ! MPIP1_HUMAN [Term] id: CCO:B0012987 name: MPIP1_HUMAN-Phosphoserine293 def: "Protein MPIP1_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:P30304] comment: by CHK1 and CHK2; xref: UniProtKB:P30304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001576 ! MPIP1_HUMAN [Term] id: CCO:B0012988 name: MPIP1_HUMAN-Phosphothreonine507 def: "Protein MPIP1_HUMAN with the residue 507 substituted with Phosphothreonine" [UniProtKB:P30304] comment: by CHK1; xref: UniProtKB:P30304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001576 ! MPIP1_HUMAN [Term] id: CCO:B0012989 name: MPIP3_HUMAN-Phosphoserine168 def: "Protein MPIP3_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:P30307] xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0012990 name: MPIP3_HUMAN-Phosphoserine216 def: "Protein MPIP3_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:P30307] comment: by CHK1, CHK2 and BRSK1; xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0012991 name: MPP8_HUMAN-Phosphoserine51 def: "Protein MPP8_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012992 name: MPP8_HUMAN-Phosphoserine136 def: "Protein MPP8_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012993 name: MPP8_HUMAN-Phosphoserine138 def: "Protein MPP8_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012994 name: MPP8_HUMAN-Phosphoserine164 def: "Protein MPP8_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012995 name: MPP8_HUMAN-Phosphoserine272 def: "Protein MPP8_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q99549] comment: Potential xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012996 name: MPP8_HUMAN-Phosphoserine319 def: "Protein MPP8_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012997 name: MPP8_HUMAN-Phosphothreonine334 def: "Protein MPP8_HUMAN with the residue 334 substituted with Phosphothreonine" [UniProtKB:Q99549] comment: Potential xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012998 name: MPP8_HUMAN-Phosphothreonine385 def: "Protein MPP8_HUMAN with the residue 385 substituted with Phosphothreonine" [UniProtKB:Q99549] comment: Potential xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0012999 name: MPP8_HUMAN-Phosphoserine392 def: "Protein MPP8_HUMAN with the residue 392 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0013000 name: MPP8_HUMAN-Phosphothreonine454 def: "Protein MPP8_HUMAN with the residue 454 substituted with Phosphothreonine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0013001 name: MPPH1_HUMAN-Phosphoserine303 def: "Protein MPPH1_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:Q96Q89] comment: By similarity xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013002 name: MPPH1_HUMAN-Phosphoserine310 def: "Protein MPPH1_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q96Q89] xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013003 name: MPPH1_HUMAN-Phosphoserine321 def: "Protein MPPH1_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q96Q89] xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013004 name: MPPH1_HUMAN-Phosphoserine323 def: "Protein MPPH1_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:Q96Q89] xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013005 name: MPPH1_HUMAN-Phosphoserine488 def: "Protein MPPH1_HUMAN with the residue 488 substituted with Phosphoserine" [UniProtKB:Q96Q89] xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013006 name: MPPH1_HUMAN-Phosphoserine999 def: "Protein MPPH1_HUMAN with the residue 999 substituted with Phosphoserine" [UniProtKB:Q96Q89] xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013007 name: MPPH1_HUMAN-Phosphoserine1071 def: "Protein MPPH1_HUMAN with the residue 1071 substituted with Phosphoserine" [UniProtKB:Q96Q89] xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013008 name: MPPH1_HUMAN-Phosphoserine1072 def: "Protein MPPH1_HUMAN with the residue 1072 substituted with Phosphoserine" [UniProtKB:Q96Q89] xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013009 name: MPPH1_HUMAN-Phosphothreonine1644 def: "Protein MPPH1_HUMAN with the residue 1644 substituted with Phosphothreonine" [UniProtKB:Q96Q89] comment: by CDC2; xref: UniProtKB:Q96Q89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002056 ! MPPH1_HUMAN [Term] id: CCO:B0013010 name: MRE11_HUMAN-Phosphothreonine74 def: "Protein MRE11_HUMAN with the residue 74 substituted with Phosphothreonine" [UniProtKB:P49959] xref: UniProtKB:P49959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:B0013011 name: MRE11_HUMAN-Phosphoserine678 def: "Protein MRE11_HUMAN with the residue 678 substituted with Phosphoserine" [UniProtKB:P49959] xref: UniProtKB:P49959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:B0013012 name: MRE11_HUMAN-Phosphoserine688 def: "Protein MRE11_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:P49959] xref: UniProtKB:P49959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:B0013013 name: MRE11_HUMAN-Phosphoserine689 def: "Protein MRE11_HUMAN with the residue 689 substituted with Phosphoserine" [UniProtKB:P49959] xref: UniProtKB:P49959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:B0013014 name: MSH2_HUMAN-Phosphoserine860 def: "Protein MSH2_HUMAN with the residue 860 substituted with Phosphoserine" [UniProtKB:P43246] xref: UniProtKB:P43246 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000082 ! four-way junction DNA binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_function CCO:F0004950 ! mispaired DNA binding relationship: has_function CCO:F0004953 ! guanine/thymine mispair binding relationship: has_function CCO:F0004955 ! dinucleotide insertion or deletion binding relationship: has_function CCO:F0004958 ! single guanine insertion binding relationship: has_function CCO:F0004959 ! single thymine insertion binding relationship: has_function CCO:F0004962 ! dinucleotide repeat insertion binding relationship: has_function CCO:F0004975 ! oxidized purine DNA binding relationship: has_function CCO:F0004985 ! MutLalpha complex binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005867 ! ADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001438 ! MutSalpha complex relationship: located_in CCO:C0001439 ! MutSbeta complex relationship: transformation_of CCO:B0001620 ! MSH2_HUMAN [Term] id: CCO:B0013015 name: MSH3_HUMAN-Phosphoserine201 def: "Protein MSH3_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:P20585] xref: UniProtKB:P20585 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005720 ! MSH3_HUMAN [Term] id: CCO:B0013016 name: MSH6_HUMAN-Phosphoserine14 def: "Protein MSH6_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013017 name: MSH6_HUMAN-Phosphoserine41 def: "Protein MSH6_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013018 name: MSH6_HUMAN-Phosphoserine43 def: "Protein MSH6_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013019 name: MSH6_HUMAN-Phosphoserine137 def: "Protein MSH6_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013020 name: MSH6_HUMAN-Phosphothreonine139 def: "Protein MSH6_HUMAN with the residue 139 substituted with Phosphothreonine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013021 name: MSH6_HUMAN-Phosphoserine219 def: "Protein MSH6_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013022 name: MSH6_HUMAN-Phosphoserine227 def: "Protein MSH6_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000082 ! four-way junction DNA binding relationship: has_function CCO:F0000094 ! purine-specific mismatch base pair DNA N-glycosylase activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_function CCO:F0004950 ! mispaired DNA binding relationship: has_function CCO:F0004953 ! guanine/thymine mispair binding relationship: has_function CCO:F0004955 ! dinucleotide insertion or deletion binding relationship: has_function CCO:F0004958 ! single guanine insertion binding relationship: has_function CCO:F0004959 ! single thymine insertion binding relationship: has_function CCO:F0004975 ! oxidized purine DNA binding relationship: has_function CCO:F0004985 ! MutLalpha complex binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005867 ! ADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001438 ! MutSalpha complex relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013023 name: MSH6_HUMAN-Phosphoserine252 def: "Protein MSH6_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013024 name: MSH6_HUMAN-Phosphoserine254 def: "Protein MSH6_HUMAN with the residue 254 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013025 name: MSH6_HUMAN-Phosphoserine256 def: "Protein MSH6_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013026 name: MSH6_HUMAN-Phosphoserine261 def: "Protein MSH6_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013027 name: MSH6_HUMAN-Phosphoserine348 def: "Protein MSH6_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013028 name: MSH6_HUMAN-Phosphoserine830 def: "Protein MSH6_HUMAN with the residue 830 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013029 name: MSH6_HUMAN-Phosphothreonine924 def: "Protein MSH6_HUMAN with the residue 924 substituted with Phosphothreonine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0013030 name: MTFR1_HUMAN-Phosphotyrosine30 def: "Protein MTFR1_HUMAN with the residue 30 substituted with Phosphotyrosine" [UniProtKB:Q15390] xref: UniProtKB:Q15390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006321 ! MTFR1_HUMAN [Term] id: CCO:B0013031 name: MTFR1_HUMAN-Phosphoserine32 def: "Protein MTFR1_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q15390] xref: UniProtKB:Q15390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006321 ! MTFR1_HUMAN [Term] id: CCO:B0013032 name: MTFR1_HUMAN-Phosphoserine33 def: "Protein MTFR1_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:Q15390] xref: UniProtKB:Q15390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0006321 ! MTFR1_HUMAN [Term] id: CCO:B0013033 name: MTFR1_HUMAN-Phosphoserine119 def: "Protein MTFR1_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q15390] xref: UniProtKB:Q15390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006321 ! MTFR1_HUMAN [Term] id: CCO:B0013034 name: MTFR1_HUMAN-Phosphoserine290 def: "Protein MTFR1_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:Q15390] xref: UniProtKB:Q15390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006321 ! MTFR1_HUMAN [Term] id: CCO:B0013035 name: MTMR6_HUMAN-Phosphoserine561 def: "Protein MTMR6_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:Q9Y217] xref: UniProtKB:Q9Y217 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006052 ! MTMR6_HUMAN [Term] id: CCO:B0013036 name: MTSS1_HUMAN-Phosphothreonine258 def: "Protein MTSS1_HUMAN with the residue 258 substituted with Phosphothreonine" [UniProtKB:O43312] xref: UniProtKB:O43312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001390 ! MTSS1_HUMAN [Term] id: CCO:B0013037 name: MTSS1_HUMAN-Phosphoserine272 def: "Protein MTSS1_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:O43312] comment: By similarity xref: UniProtKB:O43312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001390 ! MTSS1_HUMAN [Term] id: CCO:B0013038 name: MTSS1_HUMAN-Phosphoserine315 def: "Protein MTSS1_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:O43312] comment: By similarity xref: UniProtKB:O43312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001390 ! MTSS1_HUMAN [Term] id: CCO:B0013039 name: MTSS1_HUMAN-Phosphoserine316 def: "Protein MTSS1_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:O43312] comment: By similarity xref: UniProtKB:O43312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001390 ! MTSS1_HUMAN [Term] id: CCO:B0013040 name: MTSS1_HUMAN-Phosphoserine569 def: "Protein MTSS1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:O43312] comment: By similarity xref: UniProtKB:O43312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001390 ! MTSS1_HUMAN [Term] id: CCO:B0013041 name: MTUS1_HUMAN-Phosphoserine381 def: "Protein MTUS1_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9ULD2] comment: By similarity xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013042 name: MTUS1_HUMAN-Phosphoserine443 def: "Protein MTUS1_HUMAN with the residue 443 substituted with Phosphoserine" [UniProtKB:Q9ULD2] xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013043 name: MTUS1_HUMAN-Phosphoserine620 def: "Protein MTUS1_HUMAN with the residue 620 substituted with Phosphoserine" [UniProtKB:Q9ULD2] comment: By similarity xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013044 name: MTUS1_HUMAN-Phosphoserine1245 def: "Protein MTUS1_HUMAN with the residue 1245 substituted with Phosphoserine" [UniProtKB:Q9ULD2] comment: By similarity xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013045 name: MTUS1_HUMAN-Phosphoserine1255 def: "Protein MTUS1_HUMAN with the residue 1255 substituted with Phosphoserine" [UniProtKB:Q9ULD2] comment: By similarity xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013046 name: MTUS1_HUMAN-Phosphoserine1264 def: "Protein MTUS1_HUMAN with the residue 1264 substituted with Phosphoserine" [UniProtKB:Q9ULD2] xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013047 name: MTUS1_HUMAN-Phosphoserine1266 def: "Protein MTUS1_HUMAN with the residue 1266 substituted with Phosphoserine" [UniProtKB:Q9ULD2] comment: By similarity xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013048 name: MTUS1_HUMAN-Phosphoserine1268 def: "Protein MTUS1_HUMAN with the residue 1268 substituted with Phosphoserine" [UniProtKB:Q9ULD2] xref: UniProtKB:Q9ULD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002224 ! MTUS1_HUMAN [Term] id: CCO:B0013049 name: MYBB_HUMAN-Phosphothreonine266 def: "Protein MYBB_HUMAN with the residue 266 substituted with Phosphothreonine" [UniProtKB:P10244] xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013050 name: MYBB_HUMAN-Phosphoserine393 def: "Protein MYBB_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:P10244] xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013051 name: MYBB_HUMAN-Phosphothreonine440 def: "Protein MYBB_HUMAN with the residue 440 substituted with Phosphothreonine" [UniProtKB:P10244] comment: by CDK2; xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013052 name: MYBB_HUMAN-Phosphothreonine444 def: "Protein MYBB_HUMAN with the residue 444 substituted with Phosphothreonine" [UniProtKB:P10244] comment: by CDK2; xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013053 name: MYBB_HUMAN-Phosphothreonine487 def: "Protein MYBB_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:P10244] comment: by CDK2; xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013054 name: MYBB_HUMAN-Phosphothreonine494 def: "Protein MYBB_HUMAN with the residue 494 substituted with Phosphothreonine" [UniProtKB:P10244] comment: by CDK2; xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013055 name: MYBB_HUMAN-Phosphothreonine520 def: "Protein MYBB_HUMAN with the residue 520 substituted with Phosphothreonine" [UniProtKB:P10244] comment: by CDK2; xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013056 name: MYBB_HUMAN-Phosphoserine577 def: "Protein MYBB_HUMAN with the residue 577 substituted with Phosphoserine" [UniProtKB:P10244] comment: by CDK2; xref: UniProtKB:P10244 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001505 ! MYBB_HUMAN [Term] id: CCO:B0013057 name: MYC_HUMAN-Phosphothreonine8 def: "Protein MYC_HUMAN with the residue 8 substituted with Phosphothreonine" [UniProtKB:P01106] comment: by RAF; in vitro; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013058 name: MYC_HUMAN-Phosphothreonine58 def: "Protein MYC_HUMAN with the residue 58 substituted with Phosphothreonine" [UniProtKB:P01106] comment: alternate; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013059 name: MYC_HUMAN-Phosphoserine62 def: "Protein MYC_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:P01106] xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013060 name: MYC_HUMAN-N6-acetyllysine143 def: "Protein MYC_HUMAN with the residue 143 substituted with N6-acetyllysine" [UniProtKB:P01106] comment: by PCAF; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013061 name: MYC_HUMAN-N6-acetyllysine157 def: "Protein MYC_HUMAN with the residue 157 substituted with N6-acetyllysine" [UniProtKB:P01106] comment: by PCAF; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013062 name: MYC_HUMAN-N6-acetyllysine275 def: "Protein MYC_HUMAN with the residue 275 substituted with N6-acetyllysine" [UniProtKB:P01106] comment: by PCAF; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013063 name: MYC_HUMAN-N6-acetyllysine317 def: "Protein MYC_HUMAN with the residue 317 substituted with N6-acetyllysine" [UniProtKB:P01106] comment: by PCAF; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013064 name: MYC_HUMAN-N6-acetyllysine323 def: "Protein MYC_HUMAN with the residue 323 substituted with N6-acetyllysine" [UniProtKB:P01106] comment: by PCAF; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013065 name: MYC_HUMAN-N6-acetyllysine371 def: "Protein MYC_HUMAN with the residue 371 substituted with N6-acetyllysine" [UniProtKB:P01106] comment: by PCAF; xref: UniProtKB:P01106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001465 ! MYC_HUMAN [Term] id: CCO:B0013066 name: MYH14_HUMAN-N-acetylalanine2 def: "Protein MYH14_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q7Z406] xref: UniProtKB:Q7Z406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000788 ! myosin complex relationship: transformation_of CCO:B0005971 ! MYH14_HUMAN [Term] id: CCO:B0013067 name: MYL6_HUMAN-N-acetylcysteine2 def: "Protein MYL6_HUMAN with the residue 2 substituted with N-acetylcysteine" [UniProtKB:P60660] xref: UniProtKB:P60660 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:B0013068 name: MYO6_HUMAN-Phosphothreonine405 def: "Protein MYO6_HUMAN with the residue 405 substituted with Phosphothreonine" [UniProtKB:Q9UM54] comment: By similarity xref: UniProtKB:Q9UM54 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005867 ! ADP binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_function CCO:F0008237 ! minus-end directed microfilament motor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0000790 ! unconventional myosin complex relationship: located_in CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001356 ! filamentous actin relationship: located_in CCO:C0001358 ! nuclear membrane relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001949 ! clathrin-coated endocytic vesicle relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: transformation_of CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:B0013069 name: MYOZ2_HUMAN-Phosphothreonine111 def: "Protein MYOZ2_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:Q9NPC6] comment: By similarity xref: UniProtKB:Q9NPC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005250 ! MYOZ2_HUMAN [Term] id: CCO:B0013070 name: MYP0_HUMAN-Phosphoserine226 def: "Protein MYP0_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:P25189] comment: By similarity xref: UniProtKB:P25189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006337 ! MYP0_HUMAN [Term] id: CCO:B0013071 name: MYP0_HUMAN-Phosphoserine228 def: "Protein MYP0_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:P25189] comment: By similarity xref: UniProtKB:P25189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006337 ! MYP0_HUMAN [Term] id: CCO:B0013072 name: MYP0_HUMAN-Phosphoserine233 def: "Protein MYP0_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:P25189] comment: By similarity xref: UniProtKB:P25189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006337 ! MYP0_HUMAN [Term] id: CCO:B0013073 name: MYP0_HUMAN-Phosphoserine243 def: "Protein MYP0_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:P25189] comment: By similarity xref: UniProtKB:P25189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006337 ! MYP0_HUMAN [Term] id: CCO:B0013074 name: MYST2_HUMAN-Phosphoserine50 def: "Protein MYST2_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013075 name: MYST2_HUMAN-Phosphoserine52 def: "Protein MYST2_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013076 name: MYST2_HUMAN-Phosphoserine53 def: "Protein MYST2_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013077 name: MYST2_HUMAN-Phosphoserine56 def: "Protein MYST2_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013078 name: MYST2_HUMAN-Phosphoserine57 def: "Protein MYST2_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013079 name: MYST2_HUMAN-Phosphothreonine88 def: "Protein MYST2_HUMAN with the residue 88 substituted with Phosphothreonine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0000815 ! H3/H4 histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013080 name: MYST2_HUMAN-Phosphoserine99 def: "Protein MYST2_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013081 name: MYST2_HUMAN-Phosphoserine100 def: "Protein MYST2_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013082 name: MYST2_HUMAN-Phosphoserine102 def: "Protein MYST2_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013083 name: MYST2_HUMAN-Phosphoserine124 def: "Protein MYST2_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013084 name: MYST2_HUMAN-Phosphothreonine128 def: "Protein MYST2_HUMAN with the residue 128 substituted with Phosphothreonine" [UniProtKB:O95251] xref: UniProtKB:O95251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:B0013085 name: NACA_HUMAN-Phosphoserine43 def: "Protein NACA_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q13765] comment: by ILK1; By similarity xref: UniProtKB:Q13765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:B0013086 name: NACA_HUMAN-Phosphothreonine92 def: "Protein NACA_HUMAN with the residue 92 substituted with Phosphothreonine" [UniProtKB:Q13765] xref: UniProtKB:Q13765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:B0013087 name: NACA_HUMAN-Phosphothreonine159 def: "Protein NACA_HUMAN with the residue 159 substituted with Phosphothreonine" [UniProtKB:Q13765] comment: by GSK3-beta; By similarity xref: UniProtKB:Q13765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:B0013088 name: NACA_HUMAN-Phosphothreonine161 def: "Protein NACA_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:Q13765] xref: UniProtKB:Q13765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000420 ! nascent polypeptide-associated complex relationship: transformation_of CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:B0013089 name: NACA_HUMAN-Phosphoserine166 def: "Protein NACA_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q13765] xref: UniProtKB:Q13765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:B0013090 name: NACA_HUMAN-Phosphoserine186 def: "Protein NACA_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:Q13765] xref: UniProtKB:Q13765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:B0013091 name: NASP_HUMAN-Phosphoserine189 def: "Protein NASP_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013092 name: NASP_HUMAN-Phosphothreonine228 def: "Protein NASP_HUMAN with the residue 228 substituted with Phosphothreonine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013093 name: NASP_HUMAN-Phosphoserine244 def: "Protein NASP_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013094 name: NASP_HUMAN-Phosphothreonine390 def: "Protein NASP_HUMAN with the residue 390 substituted with Phosphothreonine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013095 name: NASP_HUMAN-Phosphoserine421 def: "Protein NASP_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013096 name: NASP_HUMAN-Phosphoserine451 def: "Protein NASP_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013097 name: NASP_HUMAN-Phosphothreonine464 def: "Protein NASP_HUMAN with the residue 464 substituted with Phosphothreonine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013098 name: NASP_HUMAN-Phosphothreonine477 def: "Protein NASP_HUMAN with the residue 477 substituted with Phosphothreonine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013099 name: NASP_HUMAN-Phosphoserine480 def: "Protein NASP_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013100 name: NASP_HUMAN-Phosphoserine497 def: "Protein NASP_HUMAN with the residue 497 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013101 name: NASP_HUMAN-Phosphoserine503 def: "Protein NASP_HUMAN with the residue 503 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013102 name: NASP_HUMAN-Phosphoserine726 def: "Protein NASP_HUMAN with the residue 726 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008202 ! Hsp90 protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0013103 name: NBN_HUMAN-Phosphoserine278 def: "Protein NBN_HUMAN with the residue 278 substituted with Phosphoserine" [UniProtKB:O60934] comment: by ATM; xref: UniProtKB:O60934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001421 ! NBN_HUMAN [Term] id: CCO:B0013104 name: NBN_HUMAN-Phosphoserine343 def: "Protein NBN_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:O60934] comment: by ATM; xref: UniProtKB:O60934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001421 ! NBN_HUMAN [Term] id: CCO:B0013105 name: NBN_HUMAN-Phosphoserine397 def: "Protein NBN_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:O60934] xref: UniProtKB:O60934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001421 ! NBN_HUMAN [Term] id: CCO:B0013106 name: NBN_HUMAN-Phosphoserine432 def: "Protein NBN_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:O60934] xref: UniProtKB:O60934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0001060 ! Mre11 complex relationship: located_in CCO:C0001640 ! nuclear inclusion body relationship: transformation_of CCO:B0001421 ! NBN_HUMAN [Term] id: CCO:B0013107 name: NBN_HUMAN-Phosphoserine615 def: "Protein NBN_HUMAN with the residue 615 substituted with Phosphoserine" [UniProtKB:O60934] xref: UniProtKB:O60934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001421 ! NBN_HUMAN [Term] id: CCO:B0013108 name: NCOA6_HUMAN-Phosphoserine884 def: "Protein NCOA6_HUMAN with the residue 884 substituted with Phosphoserine" [UniProtKB:Q14686] comment: by MAPK; in vitro; xref: UniProtKB:Q14686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:B0013109 name: NCOA6_HUMAN-Phosphothreonine1321 def: "Protein NCOA6_HUMAN with the residue 1321 substituted with Phosphothreonine" [UniProtKB:Q14686] xref: UniProtKB:Q14686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:B0013110 name: NCOR2_HUMAN-Phosphoserine149 def: "Protein NCOR2_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013111 name: NCOR2_HUMAN-Phosphoserine152 def: "Protein NCOR2_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013112 name: NCOR2_HUMAN-Phosphoserine215 def: "Protein NCOR2_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013113 name: NCOR2_HUMAN-Phosphothreonine553 def: "Protein NCOR2_HUMAN with the residue 553 substituted with Phosphothreonine" [UniProtKB:Q9Y618] comment: By similarity xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013114 name: NCOR2_HUMAN-Phosphoserine554 def: "Protein NCOR2_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:Q9Y618] comment: By similarity xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013115 name: NCOR2_HUMAN-Phosphoserine939 def: "Protein NCOR2_HUMAN with the residue 939 substituted with Phosphoserine" [UniProtKB:Q9Y618] comment: By similarity xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013116 name: NCOR2_HUMAN-Phosphoserine1253 def: "Protein NCOR2_HUMAN with the residue 1253 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013117 name: NCOR2_HUMAN-Phosphothreonine1383 def: "Protein NCOR2_HUMAN with the residue 1383 substituted with Phosphothreonine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013118 name: NCOR2_HUMAN-Phosphoserine1576 def: "Protein NCOR2_HUMAN with the residue 1576 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013119 name: NCOR2_HUMAN-Phosphoserine1974 def: "Protein NCOR2_HUMAN with the residue 1974 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013120 name: NCOR2_HUMAN-Phosphoserine2008 def: "Protein NCOR2_HUMAN with the residue 2008 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013121 name: NCOR2_HUMAN-Phosphoserine2049 def: "Protein NCOR2_HUMAN with the residue 2049 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013122 name: NCOR2_HUMAN-Phosphoserine2057 def: "Protein NCOR2_HUMAN with the residue 2057 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013123 name: NCOR2_HUMAN-Phosphoserine2061 def: "Protein NCOR2_HUMAN with the residue 2061 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013124 name: NCOR2_HUMAN-Phosphoserine2197 def: "Protein NCOR2_HUMAN with the residue 2197 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013125 name: NCOR2_HUMAN-Phosphoserine2200 def: "Protein NCOR2_HUMAN with the residue 2200 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013126 name: NCOR2_HUMAN-Phosphoserine2261 def: "Protein NCOR2_HUMAN with the residue 2261 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013127 name: NCOR2_HUMAN-Phosphoserine2455 def: "Protein NCOR2_HUMAN with the residue 2455 substituted with Phosphoserine" [UniProtKB:Q9Y618] comment: By similarity xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013128 name: NCOR2_HUMAN-Phosphoserine2514 def: "Protein NCOR2_HUMAN with the residue 2514 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013129 name: NCOR2_HUMAN-Phosphoserine2516 def: "Protein NCOR2_HUMAN with the residue 2516 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0013130 name: NDE1_HUMAN-Phosphothreonine246 def: "Protein NDE1_HUMAN with the residue 246 substituted with Phosphothreonine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0013131 name: NDE1_HUMAN-Phosphotyrosine279 def: "Protein NDE1_HUMAN with the residue 279 substituted with Phosphotyrosine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0013132 name: NDE1_HUMAN-Phosphoserine282 def: "Protein NDE1_HUMAN with the residue 282 substituted with Phosphoserine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0013133 name: NDE1_HUMAN-Phosphoserine306 def: "Protein NDE1_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001322 ! spindle pole centrosome relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0013134 name: NDE1_HUMAN-Phosphoserine307 def: "Protein NDE1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0013135 name: NDEL1_HUMAN-Phosphoserine215 def: "Protein NDEL1_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:Q9GZM8] comment: By similarity xref: UniProtKB:Q9GZM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005926 ! NDEL1_HUMAN [Term] id: CCO:B0013136 name: NDEL1_HUMAN-Phosphothreonine219 def: "Protein NDEL1_HUMAN with the residue 219 substituted with Phosphothreonine" [UniProtKB:Q9GZM8] comment: by CDC2 and MAPK1; xref: UniProtKB:Q9GZM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005926 ! NDEL1_HUMAN [Term] id: CCO:B0013137 name: NDEL1_HUMAN-Phosphoserine242 def: "Protein NDEL1_HUMAN with the residue 242 substituted with Phosphoserine" [UniProtKB:Q9GZM8] comment: by CDC2; xref: UniProtKB:Q9GZM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005926 ! NDEL1_HUMAN [Term] id: CCO:B0013138 name: NDEL1_HUMAN-Phosphothreonine245 def: "Protein NDEL1_HUMAN with the residue 245 substituted with Phosphothreonine" [UniProtKB:Q9GZM8] comment: by CDC2 and MAPK1; xref: UniProtKB:Q9GZM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0005926 ! NDEL1_HUMAN [Term] id: CCO:B0013139 name: NEB2_HUMAN-Phosphoserine15 def: "Protein NEB2_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q96SB3] comment: By similarity xref: UniProtKB:Q96SB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:B0013140 name: NEB2_HUMAN-Phosphoserine17 def: "Protein NEB2_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q96SB3] comment: By similarity xref: UniProtKB:Q96SB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:B0013141 name: NEB2_HUMAN-Phosphoserine94 def: "Protein NEB2_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q96SB3] comment: By similarity xref: UniProtKB:Q96SB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:B0013142 name: NEB2_HUMAN-Phosphoserine100 def: "Protein NEB2_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q96SB3] comment: By similarity xref: UniProtKB:Q96SB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:B0013143 name: NEB2_HUMAN-Phosphoserine116 def: "Protein NEB2_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q96SB3] comment: By similarity xref: UniProtKB:Q96SB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:B0013144 name: NEB2_HUMAN-Phosphoserine203 def: "Protein NEB2_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q96SB3] xref: UniProtKB:Q96SB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:B0013145 name: NEK1_HUMAN-Phosphothreonine162 def: "Protein NEK1_HUMAN with the residue 162 substituted with Phosphothreonine" [UniProtKB:Q96PY6] comment: by autocatalysis; By similarity xref: UniProtKB:Q96PY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002055 ! NEK1_HUMAN [Term] id: CCO:B0013146 name: NEK1_HUMAN-Phosphoserine664 def: "Protein NEK1_HUMAN with the residue 664 substituted with Phosphoserine" [UniProtKB:Q96PY6] comment: By similarity xref: UniProtKB:Q96PY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002055 ! NEK1_HUMAN [Term] id: CCO:B0013147 name: NEK1_HUMAN-Phosphoserine1126 def: "Protein NEK1_HUMAN with the residue 1126 substituted with Phosphoserine" [UniProtKB:Q96PY6] comment: By similarity xref: UniProtKB:Q96PY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002055 ! NEK1_HUMAN [Term] id: CCO:B0013148 name: NEK2_HUMAN-Phosphothreonine175 def: "Protein NEK2_HUMAN with the residue 175 substituted with Phosphothreonine" [UniProtKB:P51955] comment: by autocatalysis; xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0013149 name: NEK4_HUMAN-Phosphothreonine165 def: "Protein NEK4_HUMAN with the residue 165 substituted with Phosphothreonine" [UniProtKB:P51957] comment: by autocatalysis; By similarity xref: UniProtKB:P51957 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001655 ! NEK4_HUMAN [Term] id: CCO:B0013150 name: NEK4_HUMAN-Phosphoserine563 def: "Protein NEK4_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:P51957] xref: UniProtKB:P51957 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001655 ! NEK4_HUMAN [Term] id: CCO:B0013151 name: NEK9_HUMAN-Phosphothreonine210 def: "Protein NEK9_HUMAN with the residue 210 substituted with Phosphothreonine" [UniProtKB:Q8TD19] comment: by autocatalysis; Probable xref: UniProtKB:Q8TD19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001991 ! NEK9_HUMAN [Term] id: CCO:B0013152 name: NEK9_HUMAN-Phosphoserine332 def: "Protein NEK9_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:Q8TD19] xref: UniProtKB:Q8TD19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001991 ! NEK9_HUMAN [Term] id: CCO:B0013153 name: NEK9_HUMAN-Phosphothreonine333 def: "Protein NEK9_HUMAN with the residue 333 substituted with Phosphothreonine" [UniProtKB:Q8TD19] xref: UniProtKB:Q8TD19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001991 ! NEK9_HUMAN [Term] id: CCO:B0013154 name: NEK9_HUMAN-Phosphothreonine358 def: "Protein NEK9_HUMAN with the residue 358 substituted with Phosphothreonine" [UniProtKB:Q8TD19] xref: UniProtKB:Q8TD19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001991 ! NEK9_HUMAN [Term] id: CCO:B0013155 name: NEK9_HUMAN-Phosphoserine868 def: "Protein NEK9_HUMAN with the residue 868 substituted with Phosphoserine" [UniProtKB:Q8TD19] xref: UniProtKB:Q8TD19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001991 ! NEK9_HUMAN [Term] id: CCO:B0013156 name: NEK9_HUMAN-Phosphoserine869 def: "Protein NEK9_HUMAN with the residue 869 substituted with Phosphoserine" [UniProtKB:Q8TD19] xref: UniProtKB:Q8TD19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001991 ! NEK9_HUMAN [Term] id: CCO:B0013157 name: NELF_HUMAN-Phosphoserine288 def: "Protein NELF_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q6X4W1] xref: UniProtKB:Q6X4W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005972 ! NELF_HUMAN [Term] id: CCO:B0013158 name: NEP1_HUMAN-N-acetylalanine2 def: "Protein NEP1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q92979] xref: UniProtKB:Q92979 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000322 ! small nucleolar ribonucleoprotein complex relationship: transformation_of CCO:B0006260 ! NEP1_HUMAN [Term] id: CCO:B0013159 name: NF1_HUMAN-N-acetylalanine2 def: "Protein NF1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P21359] comment: By similarity xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0013160 name: NF1_HUMAN-Phosphoserine864 def: "Protein NF1_HUMAN with the residue 864 substituted with Phosphoserine" [UniProtKB:P21359] xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0013161 name: NF1_HUMAN-Phosphoserine2188 def: "Protein NF1_HUMAN with the residue 2188 substituted with Phosphoserine" [UniProtKB:P21359] xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0013162 name: NF1_HUMAN-Phosphothreonine2514 def: "Protein NF1_HUMAN with the residue 2514 substituted with Phosphothreonine" [UniProtKB:P21359] comment: By similarity xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0013163 name: NF1_HUMAN-Phosphoserine2515 def: "Protein NF1_HUMAN with the residue 2515 substituted with Phosphoserine" [UniProtKB:P21359] xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0013164 name: NFKB2_HUMAN-Phosphoserine713 def: "Protein NFKB2_HUMAN with the residue 713 substituted with Phosphoserine" [UniProtKB:Q00653] xref: UniProtKB:Q00653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001560 ! Bcl3/NF-kappaB2 complex relationship: transformation_of CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:B0013165 name: NFKB2_HUMAN-Phosphoserine715 def: "Protein NFKB2_HUMAN with the residue 715 substituted with Phosphoserine" [UniProtKB:Q00653] xref: UniProtKB:Q00653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:B0013166 name: NFKB2_HUMAN-Phosphoserine717 def: "Protein NFKB2_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:Q00653] xref: UniProtKB:Q00653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:B0013167 name: NFKB2_HUMAN-Phosphoserine866 def: "Protein NFKB2_HUMAN with the residue 866 substituted with Phosphoserine" [UniProtKB:Q00653] comment: by MAP3K14; xref: UniProtKB:Q00653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:B0013168 name: NFKB2_HUMAN-Phosphoserine870 def: "Protein NFKB2_HUMAN with the residue 870 substituted with Phosphoserine" [UniProtKB:Q00653] comment: by MAP3K14; xref: UniProtKB:Q00653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:B0013169 name: NFL_HUMAN-N-acetylserine2 def: "Protein NFL_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P07196] comment: By similarity xref: UniProtKB:P07196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:B0013170 name: NFL_HUMAN-Phosphoserine56 def: "Protein NFL_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:P07196] comment: By similarity xref: UniProtKB:P07196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:B0013171 name: NFL_HUMAN-Phosphoserine67 def: "Protein NFL_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:P07196] comment: By similarity xref: UniProtKB:P07196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:B0013172 name: NFL_HUMAN-Phosphoserine472 def: "Protein NFL_HUMAN with the residue 472 substituted with Phosphoserine" [UniProtKB:P07196] xref: UniProtKB:P07196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000441 ! neurofilament relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001584 ! TSC1-TSC2 complex relationship: transformation_of CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:B0013173 name: NH2L1_HUMAN-N-acetylthreonine2 def: "Protein NH2L1_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P55769] xref: UniProtKB:P55769 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001676 ! NH2L1_HUMAN [Term] id: CCO:B0013174 name: NIPA_HUMAN-Phosphoserine24 def: "Protein NIPA_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0013175 name: NIPA_HUMAN-Phosphothreonine28 def: "Protein NIPA_HUMAN with the residue 28 substituted with Phosphothreonine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0013176 name: NIPA_HUMAN-Phosphoserine62 def: "Protein NIPA_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q86WB0] comment: By similarity xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0013177 name: NIPA_HUMAN-Phosphoserine321 def: "Protein NIPA_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0013178 name: NIPA_HUMAN-Phosphoserine354 def: "Protein NIPA_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0013179 name: NIPA_HUMAN-Phosphoserine370 def: "Protein NIPA_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0013180 name: NIPBL_HUMAN-Phosphoserine280 def: "Protein NIPBL_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q6KC79] comment: By similarity xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013181 name: NIPBL_HUMAN-Phosphoserine318 def: "Protein NIPBL_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013182 name: NIPBL_HUMAN-Phosphoserine553 def: "Protein NIPBL_HUMAN with the residue 553 substituted with Phosphoserine" [UniProtKB:Q6KC79] comment: By similarity xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013183 name: NIPBL_HUMAN-Phosphothreonine558 def: "Protein NIPBL_HUMAN with the residue 558 substituted with Phosphothreonine" [UniProtKB:Q6KC79] comment: By similarity xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013184 name: NIPBL_HUMAN-Phosphothreonine646 def: "Protein NIPBL_HUMAN with the residue 646 substituted with Phosphothreonine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013185 name: NIPBL_HUMAN-Phosphothreonine746 def: "Protein NIPBL_HUMAN with the residue 746 substituted with Phosphothreonine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013186 name: NIPBL_HUMAN-Phosphoserine849 def: "Protein NIPBL_HUMAN with the residue 849 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013187 name: NIPBL_HUMAN-Phosphoserine850 def: "Protein NIPBL_HUMAN with the residue 850 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013188 name: NIPBL_HUMAN-Phosphoserine912 def: "Protein NIPBL_HUMAN with the residue 912 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013189 name: NIPBL_HUMAN-Phosphothreonine914 def: "Protein NIPBL_HUMAN with the residue 914 substituted with Phosphothreonine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013190 name: NIPBL_HUMAN-Phosphoserine1089 def: "Protein NIPBL_HUMAN with the residue 1089 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013191 name: NIPBL_HUMAN-Phosphoserine1090 def: "Protein NIPBL_HUMAN with the residue 1090 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013192 name: NIPBL_HUMAN-Phosphoserine1096 def: "Protein NIPBL_HUMAN with the residue 1096 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013193 name: NIPBL_HUMAN-Phosphoserine1150 def: "Protein NIPBL_HUMAN with the residue 1150 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013194 name: NIPBL_HUMAN-Phosphoserine1152 def: "Protein NIPBL_HUMAN with the residue 1152 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013195 name: NIPBL_HUMAN-Phosphoserine1154 def: "Protein NIPBL_HUMAN with the residue 1154 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013196 name: NIPBL_HUMAN-Phosphotyrosine1159 def: "Protein NIPBL_HUMAN with the residue 1159 substituted with Phosphotyrosine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013197 name: NIPBL_HUMAN-Phosphoserine2658 def: "Protein NIPBL_HUMAN with the residue 2658 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013198 name: NIPBL_HUMAN-Phosphothreonine2667 def: "Protein NIPBL_HUMAN with the residue 2667 substituted with Phosphothreonine" [UniProtKB:Q6KC79] comment: By similarity xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013199 name: NIPBL_HUMAN-Phosphoserine2672 def: "Protein NIPBL_HUMAN with the residue 2672 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0013200 name: NOG1_HUMAN-N-acetylalanine2 def: "Protein NOG1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9BZE4] xref: UniProtKB:Q9BZE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0002116 ! NOG1_HUMAN [Term] id: CCO:B0013201 name: NOG1_HUMAN-Phosphoserine468 def: "Protein NOG1_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:Q9BZE4] xref: UniProtKB:Q9BZE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002116 ! NOG1_HUMAN [Term] id: CCO:B0013202 name: NOG1_HUMAN-Phosphoserine470 def: "Protein NOG1_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:Q9BZE4] xref: UniProtKB:Q9BZE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002116 ! NOG1_HUMAN [Term] id: CCO:B0013203 name: NOG1_HUMAN-Phosphoserine472 def: "Protein NOG1_HUMAN with the residue 472 substituted with Phosphoserine" [UniProtKB:Q9BZE4] xref: UniProtKB:Q9BZE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002116 ! NOG1_HUMAN [Term] id: CCO:B0013204 name: NOL12_HUMAN-Phosphothreonine124 def: "Protein NOL12_HUMAN with the residue 124 substituted with Phosphothreonine" [UniProtKB:Q9UGY1] xref: UniProtKB:Q9UGY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006336 ! NOL12_HUMAN [Term] id: CCO:B0013205 name: NOL12_HUMAN-Phosphoserine139 def: "Protein NOL12_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q9UGY1] xref: UniProtKB:Q9UGY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006336 ! NOL12_HUMAN [Term] id: CCO:B0013206 name: NOL12_HUMAN-Phosphoserine140 def: "Protein NOL12_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q9UGY1] xref: UniProtKB:Q9UGY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0006336 ! NOL12_HUMAN [Term] id: CCO:B0013207 name: NOL12_HUMAN-Phosphothreonine141 def: "Protein NOL12_HUMAN with the residue 141 substituted with Phosphothreonine" [UniProtKB:Q9UGY1] xref: UniProtKB:Q9UGY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006336 ! NOL12_HUMAN [Term] id: CCO:B0013208 name: NOL1_HUMAN-Phosphoserine58 def: "Protein NOL1_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013209 name: NOL1_HUMAN-Phosphoserine67 def: "Protein NOL1_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013210 name: NOL1_HUMAN-Phosphoserine111 def: "Protein NOL1_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013211 name: NOL1_HUMAN-Phosphoserine120 def: "Protein NOL1_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013212 name: NOL1_HUMAN-Phosphoserine134 def: "Protein NOL1_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013213 name: NOL1_HUMAN-Phosphothreonine140 def: "Protein NOL1_HUMAN with the residue 140 substituted with Phosphothreonine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013214 name: NOL1_HUMAN-Phosphoserine150 def: "Protein NOL1_HUMAN with the residue 150 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013215 name: NOL1_HUMAN-Phosphoserine181 def: "Protein NOL1_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013216 name: NOL1_HUMAN-Phosphothreonine185 def: "Protein NOL1_HUMAN with the residue 185 substituted with Phosphothreonine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013217 name: NOL1_HUMAN-Phosphothreonine195 def: "Protein NOL1_HUMAN with the residue 195 substituted with Phosphothreonine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013218 name: NOL1_HUMAN-Phosphothreonine603 def: "Protein NOL1_HUMAN with the residue 603 substituted with Phosphothreonine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013219 name: NOL1_HUMAN-Phosphoserine732 def: "Protein NOL1_HUMAN with the residue 732 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013220 name: NOL1_HUMAN-Phosphoserine734 def: "Protein NOL1_HUMAN with the residue 734 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0013221 name: NOLC1_HUMAN-Phosphoserine83 def: "Protein NOLC1_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013222 name: NOLC1_HUMAN-Phosphoserine84 def: "Protein NOLC1_HUMAN with the residue 84 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013223 name: NOLC1_HUMAN-Phosphoserine85 def: "Protein NOLC1_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013224 name: NOLC1_HUMAN-Phosphoserine87 def: "Protein NOLC1_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013225 name: NOLC1_HUMAN-Phosphoserine90 def: "Protein NOLC1_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013226 name: NOLC1_HUMAN-Phosphoserine91 def: "Protein NOLC1_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013227 name: NOLC1_HUMAN-Phosphoserine397 def: "Protein NOLC1_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013228 name: NOLC1_HUMAN-Phosphoserine508 def: "Protein NOLC1_HUMAN with the residue 508 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013229 name: NOLC1_HUMAN-Phosphoserine538 def: "Protein NOLC1_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013230 name: NOLC1_HUMAN-Phosphoserine563 def: "Protein NOLC1_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013231 name: NOLC1_HUMAN-Phosphothreonine607 def: "Protein NOLC1_HUMAN with the residue 607 substituted with Phosphothreonine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013232 name: NOLC1_HUMAN-Phosphothreonine610 def: "Protein NOLC1_HUMAN with the residue 610 substituted with Phosphothreonine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013233 name: NOLC1_HUMAN-Phosphoserine623 def: "Protein NOLC1_HUMAN with the residue 623 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013234 name: NOLC1_HUMAN-Phosphoserine643 def: "Protein NOLC1_HUMAN with the residue 643 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013235 name: NOLC1_HUMAN-Phosphoserine698 def: "Protein NOLC1_HUMAN with the residue 698 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0013236 name: NONO_HUMAN-Phosphothreonine428 def: "Protein NONO_HUMAN with the residue 428 substituted with Phosphothreonine" [UniProtKB:Q15233] xref: UniProtKB:Q15233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005234 ! NONO_HUMAN [Term] id: CCO:B0013237 name: NONO_HUMAN-Phosphothreonine450 def: "Protein NONO_HUMAN with the residue 450 substituted with Phosphothreonine" [UniProtKB:Q15233] xref: UniProtKB:Q15233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005234 ! NONO_HUMAN [Term] id: CCO:B0013238 name: NOTC2_HUMAN-Phosphothreonine1808 def: "Protein NOTC2_HUMAN with the residue 1808 substituted with Phosphothreonine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0013239 name: NOTC2_HUMAN-Phosphoserine1841 def: "Protein NOTC2_HUMAN with the residue 1841 substituted with Phosphoserine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0013240 name: NOTC2_HUMAN-Phosphoserine1842 def: "Protein NOTC2_HUMAN with the residue 1842 substituted with Phosphoserine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0013241 name: NOTC2_HUMAN-Phosphoserine1845 def: "Protein NOTC2_HUMAN with the residue 1845 substituted with Phosphoserine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0013242 name: NOTC2_HUMAN-Phosphoserine2070 def: "Protein NOTC2_HUMAN with the residue 2070 substituted with Phosphoserine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0013243 name: NOTC2_HUMAN-Phosphoserine2078 def: "Protein NOTC2_HUMAN with the residue 2078 substituted with Phosphoserine" [UniProtKB:Q04721] comment: By similarity xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0013244 name: NP1L1_HUMAN-Phosphoserine10 def: "Protein NP1L1_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P55209] xref: UniProtKB:P55209 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000281 ! chromatin assembly complex relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:B0013245 name: NP1L1_HUMAN-Phosphothreonine62 def: "Protein NP1L1_HUMAN with the residue 62 substituted with Phosphothreonine" [UniProtKB:P55209] xref: UniProtKB:P55209 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:B0013246 name: NPM_HUMAN-Phosphoserine4 def: "Protein NPM_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013247 name: NPM_HUMAN-Phosphoserine10 def: "Protein NPM_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013248 name: NPM_HUMAN-Phosphoserine70 def: "Protein NPM_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013249 name: NPM_HUMAN-Phosphothreonine75 def: "Protein NPM_HUMAN with the residue 75 substituted with Phosphothreonine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013250 name: NPM_HUMAN-Phosphothreonine95 def: "Protein NPM_HUMAN with the residue 95 substituted with Phosphothreonine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013251 name: NPM_HUMAN-Phosphoserine106 def: "Protein NPM_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:P06748] comment: By similarity xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013252 name: NPM_HUMAN-Phosphoserine125 def: "Protein NPM_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013253 name: NPM_HUMAN-Phosphoserine137 def: "Protein NPM_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013254 name: NPM_HUMAN-N6-acetyllysine150 def: "Protein NPM_HUMAN with the residue 150 substituted with N6-acetyllysine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013255 name: NPM_HUMAN-N6-acetyllysine154 def: "Protein NPM_HUMAN with the residue 154 substituted with N6-acetyllysine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013256 name: NPM_HUMAN-Phosphothreonine199 def: "Protein NPM_HUMAN with the residue 199 substituted with Phosphothreonine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013257 name: NPM_HUMAN-N6-acetyllysine212 def: "Protein NPM_HUMAN with the residue 212 substituted with N6-acetyllysine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013258 name: NPM_HUMAN-Phosphothreonine234 def: "Protein NPM_HUMAN with the residue 234 substituted with Phosphothreonine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013259 name: NPM_HUMAN-Phosphothreonine237 def: "Protein NPM_HUMAN with the residue 237 substituted with Phosphothreonine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013260 name: NPM_HUMAN-Phosphoserine254 def: "Protein NPM_HUMAN with the residue 254 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013261 name: NPM_HUMAN-Phosphoserine260 def: "Protein NPM_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0013262 name: NSL1_HUMAN-Phosphoserine24 def: "Protein NSL1_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q96IY1] xref: UniProtKB:Q96IY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002043 ! NSL1_HUMAN [Term] id: CCO:B0013263 name: NSL1_HUMAN-Phosphothreonine242 def: "Protein NSL1_HUMAN with the residue 242 substituted with Phosphothreonine" [UniProtKB:Q96IY1] xref: UniProtKB:Q96IY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000092 ! MIS12/MIND type complex relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002043 ! NSL1_HUMAN [Term] id: CCO:B0013264 name: NUAK2_HUMAN-Phosphothreonine208 def: "Protein NUAK2_HUMAN with the residue 208 substituted with Phosphothreonine" [UniProtKB:Q9H093] xref: UniProtKB:Q9H093 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005874 ! NUAK2_HUMAN [Term] id: CCO:B0013265 name: NUAK2_HUMAN-Phosphoserine212 def: "Protein NUAK2_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q9H093] comment: By similarity xref: UniProtKB:Q9H093 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005874 ! NUAK2_HUMAN [Term] id: CCO:B0013266 name: NUAK2_HUMAN-Phosphoserine377 def: "Protein NUAK2_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q9H093] comment: By similarity xref: UniProtKB:Q9H093 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0005874 ! NUAK2_HUMAN [Term] id: CCO:B0013267 name: NUAK2_HUMAN-Phosphoserine386 def: "Protein NUAK2_HUMAN with the residue 386 substituted with Phosphoserine" [UniProtKB:Q9H093] comment: By similarity xref: UniProtKB:Q9H093 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005874 ! NUAK2_HUMAN [Term] id: CCO:B0013268 name: NUAK2_HUMAN-Phosphoserine585 def: "Protein NUAK2_HUMAN with the residue 585 substituted with Phosphoserine" [UniProtKB:Q9H093] comment: By similarity xref: UniProtKB:Q9H093 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005874 ! NUAK2_HUMAN [Term] id: CCO:B0013269 name: NUCL_HUMAN-Phosphoserine28 def: "Protein NUCL_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013270 name: NUCL_HUMAN-Phosphoserine34 def: "Protein NUCL_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000489 ! cell cortex relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013271 name: NUCL_HUMAN-Phosphoserine41 def: "Protein NUCL_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013272 name: NUCL_HUMAN-Phosphoserine42 def: "Protein NUCL_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013273 name: NUCL_HUMAN-Phosphoserine67 def: "Protein NUCL_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013274 name: NUCL_HUMAN-Phosphothreonine69 def: "Protein NUCL_HUMAN with the residue 69 substituted with Phosphothreonine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013275 name: NUCL_HUMAN-Phosphothreonine76 def: "Protein NUCL_HUMAN with the residue 76 substituted with Phosphothreonine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013276 name: NUCL_HUMAN-Phosphothreonine121 def: "Protein NUCL_HUMAN with the residue 121 substituted with Phosphothreonine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013277 name: NUCL_HUMAN-Phosphoserine145 def: "Protein NUCL_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013278 name: NUCL_HUMAN-Phosphoserine153 def: "Protein NUCL_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013279 name: NUCL_HUMAN-Phosphoserine184 def: "Protein NUCL_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013280 name: NUCL_HUMAN-Phosphothreonine214 def: "Protein NUCL_HUMAN with the residue 214 substituted with Phosphothreonine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013281 name: NUCL_HUMAN-Phosphoserine563 def: "Protein NUCL_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013282 name: NUCL_HUMAN-Phosphoserine580 def: "Protein NUCL_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013283 name: NUCL_HUMAN-Phosphoserine619 def: "Protein NUCL_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0013284 name: NUDC3_HUMAN-Phosphoserine146 def: "Protein NUDC3_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q8IVD9] xref: UniProtKB:Q8IVD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005198 ! NUDC3_HUMAN [Term] id: CCO:B0013285 name: NUDC3_HUMAN-Phosphoserine340 def: "Protein NUDC3_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q8IVD9] xref: UniProtKB:Q8IVD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005198 ! NUDC3_HUMAN [Term] id: CCO:B0013286 name: NUDC_HUMAN-Phosphoserine139 def: "Protein NUDC_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q9Y266] xref: UniProtKB:Q9Y266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002250 ! NUDC_HUMAN [Term] id: CCO:B0013287 name: NUDC_HUMAN-Phosphothreonine145 def: "Protein NUDC_HUMAN with the residue 145 substituted with Phosphothreonine" [UniProtKB:Q9Y266] xref: UniProtKB:Q9Y266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002250 ! NUDC_HUMAN [Term] id: CCO:B0013288 name: NUDC_HUMAN-Phosphoserine274 def: "Protein NUDC_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q9Y266] comment: by PLK1; xref: UniProtKB:Q9Y266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0002250 ! NUDC_HUMAN [Term] id: CCO:B0013289 name: NUDC_HUMAN-Phosphoserine285 def: "Protein NUDC_HUMAN with the residue 285 substituted with Phosphoserine" [UniProtKB:Q9Y266] xref: UniProtKB:Q9Y266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002250 ! NUDC_HUMAN [Term] id: CCO:B0013290 name: NUDC_HUMAN-Phosphoserine326 def: "Protein NUDC_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:Q9Y266] comment: by PLK1; xref: UniProtKB:Q9Y266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002250 ! NUDC_HUMAN [Term] id: CCO:B0013291 name: NUF2_HUMAN-Phosphoserine247 def: "Protein NUF2_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:Q9BZD4] xref: UniProtKB:Q9BZD4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002115 ! NUF2_HUMAN [Term] id: CCO:B0013292 name: NUF2_HUMAN-Phosphothreonine261 def: "Protein NUF2_HUMAN with the residue 261 substituted with Phosphothreonine" [UniProtKB:Q9BZD4] xref: UniProtKB:Q9BZD4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002115 ! NUF2_HUMAN [Term] id: CCO:B0013293 name: NUMA1_HUMAN-Phosphoserine169 def: "Protein NUMA1_HUMAN with the residue 169 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013294 name: NUMA1_HUMAN-Phosphoserine172 def: "Protein NUMA1_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013295 name: NUMA1_HUMAN-Phosphoserine200 def: "Protein NUMA1_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013296 name: NUMA1_HUMAN-Phosphoserine203 def: "Protein NUMA1_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013297 name: NUMA1_HUMAN-Phosphothreonine211 def: "Protein NUMA1_HUMAN with the residue 211 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013298 name: NUMA1_HUMAN-Phosphoserine388 def: "Protein NUMA1_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013299 name: NUMA1_HUMAN-Phosphoserine395 def: "Protein NUMA1_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013300 name: NUMA1_HUMAN-Phosphoserine820 def: "Protein NUMA1_HUMAN with the residue 820 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013301 name: NUMA1_HUMAN-Phosphothreonine963 def: "Protein NUMA1_HUMAN with the residue 963 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013302 name: NUMA1_HUMAN-Phosphoserine1262 def: "Protein NUMA1_HUMAN with the residue 1262 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013303 name: NUMA1_HUMAN-Phosphoserine1601 def: "Protein NUMA1_HUMAN with the residue 1601 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013304 name: NUMA1_HUMAN-Phosphoserine1721 def: "Protein NUMA1_HUMAN with the residue 1721 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013305 name: NUMA1_HUMAN-Phosphoserine1724 def: "Protein NUMA1_HUMAN with the residue 1724 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013306 name: NUMA1_HUMAN-Phosphoserine1728 def: "Protein NUMA1_HUMAN with the residue 1728 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013307 name: NUMA1_HUMAN-Phosphothreonine1733 def: "Protein NUMA1_HUMAN with the residue 1733 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013308 name: NUMA1_HUMAN-Phosphoserine1757 def: "Protein NUMA1_HUMAN with the residue 1757 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013309 name: NUMA1_HUMAN-Phosphoserine1760 def: "Protein NUMA1_HUMAN with the residue 1760 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013310 name: NUMA1_HUMAN-Phosphoserine1769 def: "Protein NUMA1_HUMAN with the residue 1769 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013311 name: NUMA1_HUMAN-Phosphoserine1772 def: "Protein NUMA1_HUMAN with the residue 1772 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013312 name: NUMA1_HUMAN-Phosphotyrosine1774 def: "Protein NUMA1_HUMAN with the residue 1774 substituted with Phosphotyrosine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013313 name: NUMA1_HUMAN-Phosphothreonine1776 def: "Protein NUMA1_HUMAN with the residue 1776 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013314 name: NUMA1_HUMAN-Phosphoserine1830 def: "Protein NUMA1_HUMAN with the residue 1830 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013315 name: NUMA1_HUMAN-Phosphoserine1833 def: "Protein NUMA1_HUMAN with the residue 1833 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013316 name: NUMA1_HUMAN-Phosphoserine1834 def: "Protein NUMA1_HUMAN with the residue 1834 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013317 name: NUMA1_HUMAN-Phosphoserine1840 def: "Protein NUMA1_HUMAN with the residue 1840 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013318 name: NUMA1_HUMAN-Phosphoserine1847 def: "Protein NUMA1_HUMAN with the residue 1847 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013319 name: NUMA1_HUMAN-Phosphoserine1853 def: "Protein NUMA1_HUMAN with the residue 1853 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013320 name: NUMA1_HUMAN-Phosphoserine1862 def: "Protein NUMA1_HUMAN with the residue 1862 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013321 name: NUMA1_HUMAN-Phosphoserine1872 def: "Protein NUMA1_HUMAN with the residue 1872 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013322 name: NUMA1_HUMAN-Phosphoserine1945 def: "Protein NUMA1_HUMAN with the residue 1945 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013323 name: NUMA1_HUMAN-Phosphothreonine2000 def: "Protein NUMA1_HUMAN with the residue 2000 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013324 name: NUMA1_HUMAN-Phosphothreonine2055 def: "Protein NUMA1_HUMAN with the residue 2055 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013325 name: NUMA1_HUMAN-Phosphoserine2077 def: "Protein NUMA1_HUMAN with the residue 2077 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000436 ! spindle microtubule relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013326 name: NUMA1_HUMAN-Phosphothreonine2106 def: "Protein NUMA1_HUMAN with the residue 2106 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0013327 name: NUSAP_HUMAN-Phosphoserine124 def: "Protein NUSAP_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0013328 name: NUSAP_HUMAN-Phosphoserine135 def: "Protein NUSAP_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0013329 name: NUSAP_HUMAN-Phosphothreonine314 def: "Protein NUSAP_HUMAN with the residue 314 substituted with Phosphothreonine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0013330 name: ORC1_HUMAN-Phosphoserine417 def: "Protein ORC1_HUMAN with the residue 417 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0013331 name: ORC1_HUMAN-Phosphoserine419 def: "Protein ORC1_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0013332 name: ORC1_HUMAN-Phosphoserine420 def: "Protein ORC1_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0013333 name: ORC1_HUMAN-Phosphoserine421 def: "Protein ORC1_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0013334 name: ORC3_HUMAN-Phosphoserine208 def: "Protein ORC3_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q9UBD5] xref: UniProtKB:Q9UBD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000280 ! DNA replication origin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000269 ! nuclear origin of replication recognition complex relationship: transformation_of CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:B0013335 name: ORC3_HUMAN-Phosphoserine516 def: "Protein ORC3_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q9UBD5] xref: UniProtKB:Q9UBD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:B0013336 name: ORC6_HUMAN-Phosphothreonine195 def: "Protein ORC6_HUMAN with the residue 195 substituted with Phosphothreonine" [UniProtKB:Q9Y5N6] xref: UniProtKB:Q9Y5N6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000269 ! nuclear origin of replication recognition complex relationship: transformation_of CCO:B0005388 ! ORC6_HUMAN [Term] id: CCO:B0013337 name: ORC6_HUMAN-Phosphothreonine229 def: "Protein ORC6_HUMAN with the residue 229 substituted with Phosphothreonine" [UniProtKB:Q9Y5N6] xref: UniProtKB:Q9Y5N6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005388 ! ORC6_HUMAN [Term] id: CCO:B0013338 name: OSBL1_HUMAN-Phosphoserine499 def: "Protein OSBL1_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:Q9BXW6] xref: UniProtKB:Q9BXW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006009 ! OSBL1_HUMAN [Term] id: CCO:B0013339 name: P3C2A_HUMAN-Phosphoserine259 def: "Protein P3C2A_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:O00443] xref: UniProtKB:O00443 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0005554 ! phosphatidylinositol-4-phosphate 3-kinase activity relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0006071 ! P3C2A_HUMAN [Term] id: CCO:B0013340 name: P53_HUMAN-Phosphoserine15 def: "Protein P53_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:P04637] comment: by PRPK; xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013341 name: P53_HUMAN-Phosphothreonine18 def: "Protein P53_HUMAN with the residue 18 substituted with Phosphothreonine" [UniProtKB:P04637] comment: by VRK1; xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013342 name: P53_HUMAN-Phosphoserine46 def: "Protein P53_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:P04637] comment: by HIPK2; xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013343 name: P53_HUMAN-Phosphothreonine55 def: "Protein P53_HUMAN with the residue 55 substituted with Phosphothreonine" [UniProtKB:P04637] comment: by TAF1; xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013344 name: P53_HUMAN-Phosphoserine99 def: "Protein P53_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:P04637] xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013345 name: P53_HUMAN-N6-acetyllysine305 def: "Protein P53_HUMAN with the residue 305 substituted with N6-acetyllysine" [UniProtKB:P04637] xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013346 name: P53_HUMAN-Phosphoserine315 def: "Protein P53_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:P04637] comment: by CDC2; xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013347 name: P53_HUMAN-N6-acetyllysine373 def: "Protein P53_HUMAN with the residue 373 substituted with N6-acetyllysine" [UniProtKB:P04637] xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013348 name: P53_HUMAN-N6-acetyllysine382 def: "Protein P53_HUMAN with the residue 382 substituted with N6-acetyllysine" [UniProtKB:P04637] xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013349 name: P53_HUMAN-O-(5'-phospho-RNA)-serine392 def: "Protein P53_HUMAN with the residue 392 substituted with O-(5'-phospho-RNA)-serine" [UniProtKB:P04637] xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013350 name: P53_HUMAN-Phosphoserine392 def: "Protein P53_HUMAN with the residue 392 substituted with Phosphoserine" [UniProtKB:P04637] comment: by CK2; xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0013351 name: P66A_HUMAN-Phosphoserine100 def: "Protein P66A_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0013352 name: P66A_HUMAN-Phosphoserine107 def: "Protein P66A_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0013353 name: P66A_HUMAN-Phosphoserine114 def: "Protein P66A_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000805 ! NuRD complex relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0013354 name: P66A_HUMAN-Phosphoserine546 def: "Protein P66A_HUMAN with the residue 546 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0013355 name: P66A_HUMAN-Phosphoserine598 def: "Protein P66A_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0013356 name: P66B_HUMAN-Phosphothreonine120 def: "Protein P66B_HUMAN with the residue 120 substituted with Phosphothreonine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0013357 name: P66B_HUMAN-Phosphoserine122 def: "Protein P66B_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0013358 name: P66B_HUMAN-Phosphoserine129 def: "Protein P66B_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0013359 name: P66B_HUMAN-Phosphoserine135 def: "Protein P66B_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0013360 name: P66B_HUMAN-Phosphoserine486 def: "Protein P66B_HUMAN with the residue 486 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0013361 name: P73_HUMAN-Phosphotyrosine99 def: "Protein P73_HUMAN with the residue 99 substituted with Phosphotyrosine" [UniProtKB:O15350] comment: by ABL; in isoform Beta; xref: UniProtKB:O15350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001374 ! P73_HUMAN [Term] id: CCO:B0013362 name: P80C_HUMAN-Phosphothreonine122 def: "Protein P80C_HUMAN with the residue 122 substituted with Phosphothreonine" [UniProtKB:P38432] xref: UniProtKB:P38432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:B0013363 name: P80C_HUMAN-Phosphothreonine303 def: "Protein P80C_HUMAN with the residue 303 substituted with Phosphothreonine" [UniProtKB:P38432] xref: UniProtKB:P38432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:B0013364 name: P80C_HUMAN-Phosphoserine489 def: "Protein P80C_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:P38432] xref: UniProtKB:P38432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:B0013365 name: PA2G4_HUMAN-N-acetylserine2 def: "Protein PA2G4_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9UQ80] xref: UniProtKB:Q9UQ80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:B0013366 name: PA2G4_HUMAN-Phosphoserine2 def: "Protein PA2G4_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q9UQ80] xref: UniProtKB:Q9UQ80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000687 ! methionyl aminopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001785 ! metalloexopeptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:B0013367 name: PA2G4_HUMAN-Phosphothreonine366 def: "Protein PA2G4_HUMAN with the residue 366 substituted with Phosphothreonine" [UniProtKB:Q9UQ80] comment: Probable xref: UniProtKB:Q9UQ80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:B0013368 name: PA2G4_HUMAN-Phosphothreonine386 def: "Protein PA2G4_HUMAN with the residue 386 substituted with Phosphothreonine" [UniProtKB:Q9UQ80] xref: UniProtKB:Q9UQ80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:B0013369 name: PABP1_HUMAN-Phosphotyrosine364 def: "Protein PABP1_HUMAN with the residue 364 substituted with Phosphotyrosine" [UniProtKB:P11940] xref: UniProtKB:P11940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005854 ! PABP1_HUMAN [Term] id: CCO:B0013370 name: PABP1_HUMAN-arginine455 def: "Protein PABP1_HUMAN with the residue 455 substituted with arginine" [UniProtKB:P11940] comment: by CARM1; partial; Probable xref: UniProtKB:P11940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005854 ! PABP1_HUMAN [Term] id: CCO:B0013371 name: PABP1_HUMAN-arginine460 def: "Protein PABP1_HUMAN with the residue 460 substituted with arginine" [UniProtKB:P11940] comment: by CARM1; partial; Probable xref: UniProtKB:P11940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005854 ! PABP1_HUMAN [Term] id: CCO:B0013372 name: PABP1_HUMAN-Omega-N-methylated arginine493 def: "Protein PABP1_HUMAN with the residue 493 substituted with Omega-N-methylated arginine" [UniProtKB:P11940] xref: UniProtKB:P11940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001745 ! poly(A) binding relationship: has_function CCO:F0001952 ! translation activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005854 ! PABP1_HUMAN [Term] id: CCO:B0013373 name: PACA_HUMAN-Leucine amide158 def: "Protein PACA_HUMAN with the residue 158 substituted with Leucine amide" [UniProtKB:P18509] xref: UniProtKB:P18509 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001532 ! PACA_HUMAN [Term] id: CCO:B0013374 name: PACA_HUMAN-Lysine amide169 def: "Protein PACA_HUMAN with the residue 169 substituted with Lysine amide" [UniProtKB:P18509] xref: UniProtKB:P18509 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0001532 ! PACA_HUMAN [Term] id: CCO:B0013375 name: PAK1_HUMAN-Phosphoserine21 def: "Protein PAK1_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q13153] comment: by autocatalysis; By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013376 name: PAK1_HUMAN-Phosphoserine57 def: "Protein PAK1_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:Q13153] comment: by autocatalysis; By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013377 name: PAK1_HUMAN-Phosphothreonine84 def: "Protein PAK1_HUMAN with the residue 84 substituted with Phosphothreonine" [UniProtKB:Q13153] comment: by OXSR1; By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013378 name: PAK1_HUMAN-Phosphoserine144 def: "Protein PAK1_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q13153] comment: by autocatalysis; By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013379 name: PAK1_HUMAN-Phosphoserine149 def: "Protein PAK1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q13153] comment: by autocatalysis; By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013380 name: PAK1_HUMAN-Phosphoserine199 def: "Protein PAK1_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q13153] comment: by autocatalysis; By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013381 name: PAK1_HUMAN-Phosphoserine204 def: "Protein PAK1_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:Q13153] comment: by autocatalysis; By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013382 name: PAK1_HUMAN-Phosphothreonine212 def: "Protein PAK1_HUMAN with the residue 212 substituted with Phosphothreonine" [UniProtKB:Q13153] xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013383 name: PAK1_HUMAN-Phosphoserine220 def: "Protein PAK1_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q13153] comment: By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013384 name: PAK1_HUMAN-Phosphoserine223 def: "Protein PAK1_HUMAN with the residue 223 substituted with Phosphoserine" [UniProtKB:Q13153] comment: By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013385 name: PAK1_HUMAN-Phosphothreonine225 def: "Protein PAK1_HUMAN with the residue 225 substituted with Phosphothreonine" [UniProtKB:Q13153] comment: By similarity xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013386 name: PAK1_HUMAN-Phosphothreonine423 def: "Protein PAK1_HUMAN with the residue 423 substituted with Phosphothreonine" [UniProtKB:Q13153] comment: by autocatalysis; Probable xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0013387 name: PAR3L_HUMAN-Phosphoserine368 def: "Protein PAR3L_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q8TEW8] comment: By similarity xref: UniProtKB:Q8TEW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001997 ! PAR3L_HUMAN [Term] id: CCO:B0013388 name: PAR3L_HUMAN-Phosphoserine730 def: "Protein PAR3L_HUMAN with the residue 730 substituted with Phosphoserine" [UniProtKB:Q8TEW8] comment: By similarity xref: UniProtKB:Q8TEW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0001997 ! PAR3L_HUMAN [Term] id: CCO:B0013389 name: PAR3L_HUMAN-Phosphoserine746 def: "Protein PAR3L_HUMAN with the residue 746 substituted with Phosphoserine" [UniProtKB:Q8TEW8] comment: By similarity xref: UniProtKB:Q8TEW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001997 ! PAR3L_HUMAN [Term] id: CCO:B0013390 name: PAR3L_HUMAN-Phosphoserine749 def: "Protein PAR3L_HUMAN with the residue 749 substituted with Phosphoserine" [UniProtKB:Q8TEW8] comment: By similarity xref: UniProtKB:Q8TEW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001997 ! PAR3L_HUMAN [Term] id: CCO:B0013391 name: PARD3_HUMAN-Phosphoserine144 def: "Protein PARD3_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0013392 name: PARD3_HUMAN-Phosphoserine383 def: "Protein PARD3_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0013393 name: PARD3_HUMAN-Phosphoserine717 def: "Protein PARD3_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0013394 name: PARD3_HUMAN-Phosphoserine827 def: "Protein PARD3_HUMAN with the residue 827 substituted with Phosphoserine" [UniProtKB:Q8TEW0] comment: By similarity xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0013395 name: PARD3_HUMAN-Phosphotyrosine1127 def: "Protein PARD3_HUMAN with the residue 1127 substituted with Phosphotyrosine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0013396 name: PARK7_HUMAN-Phosphotyrosine67 def: "Protein PARK7_HUMAN with the residue 67 substituted with Phosphotyrosine" [UniProtKB:Q99497] xref: UniProtKB:Q99497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005443 ! PARK7_HUMAN [Term] id: CCO:B0013397 name: PARK7_HUMAN-Cysteine sulfinic acid (-SO2H)106 def: "Protein PARK7_HUMAN with the residue 106 substituted with Cysteine sulfinic acid (-SO2H)" [UniProtKB:Q99497] xref: UniProtKB:Q99497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005443 ! PARK7_HUMAN [Term] id: CCO:B0013398 name: PARN_HUMAN-Phosphoserine163 def: "Protein PARN_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:O95453] xref: UniProtKB:O95453 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005347 ! PARN_HUMAN [Term] id: CCO:B0013399 name: PARN_HUMAN-Phosphoserine557 def: "Protein PARN_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:O95453] xref: UniProtKB:O95453 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000314 ! mRNA 3'-UTR binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0000931 ! poly(A)-specific ribonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005347 ! PARN_HUMAN [Term] id: CCO:B0013400 name: PARN_HUMAN-Phosphoserine587 def: "Protein PARN_HUMAN with the residue 587 substituted with Phosphoserine" [UniProtKB:O95453] comment: By similarity xref: UniProtKB:O95453 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005347 ! PARN_HUMAN [Term] id: CCO:B0013401 name: PARN_HUMAN-Phosphoserine619 def: "Protein PARN_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:O95453] xref: UniProtKB:O95453 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005347 ! PARN_HUMAN [Term] id: CCO:B0013402 name: PARP1_HUMAN-Phosphoserine179 def: "Protein PARP1_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:P09874] xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013403 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid407 def: "Protein PARP1_HUMAN with the residue 407 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013404 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid413 def: "Protein PARP1_HUMAN with the residue 413 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013405 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid435 def: "Protein PARP1_HUMAN with the residue 435 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013406 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid437 def: "Protein PARP1_HUMAN with the residue 437 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013407 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid444 def: "Protein PARP1_HUMAN with the residue 444 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013408 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid445 def: "Protein PARP1_HUMAN with the residue 445 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013409 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid448 def: "Protein PARP1_HUMAN with the residue 448 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013410 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid456 def: "Protein PARP1_HUMAN with the residue 456 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013411 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid471 def: "Protein PARP1_HUMAN with the residue 471 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013412 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid484 def: "Protein PARP1_HUMAN with the residue 484 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013413 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid488 def: "Protein PARP1_HUMAN with the residue 488 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013414 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid491 def: "Protein PARP1_HUMAN with the residue 491 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013415 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid513 def: "Protein PARP1_HUMAN with the residue 513 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013416 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid514 def: "Protein PARP1_HUMAN with the residue 514 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013417 name: PARP1_HUMAN-PolyADP-ribosyl glutamic acid520 def: "Protein PARP1_HUMAN with the residue 520 substituted with PolyADP-ribosyl glutamic acid" [UniProtKB:P09874] comment: Potential xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0013418 name: PAXI_HUMAN-Phosphotyrosine31 def: "Protein PAXI_HUMAN with the residue 31 substituted with Phosphotyrosine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0013419 name: PAXI_HUMAN-Phosphotyrosine88 def: "Protein PAXI_HUMAN with the residue 88 substituted with Phosphotyrosine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0013420 name: PAXI_HUMAN-Phosphoserine106 def: "Protein PAXI_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0013421 name: PAXI_HUMAN-Phosphoserine109 def: "Protein PAXI_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:P49023] comment: By similarity xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0013422 name: PAXI_HUMAN-Phosphotyrosine118 def: "Protein PAXI_HUMAN with the residue 118 substituted with Phosphotyrosine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0013423 name: PAXI_HUMAN-Phosphotyrosine181 def: "Protein PAXI_HUMAN with the residue 181 substituted with Phosphotyrosine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0013424 name: PAXI_HUMAN-Phosphoserine303 def: "Protein PAXI_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0013425 name: PB1_HUMAN-Phosphoserine39 def: "Protein PB1_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0013426 name: PB1_HUMAN-Phosphotyrosine54 def: "Protein PB1_HUMAN with the residue 54 substituted with Phosphotyrosine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0013427 name: PB1_HUMAN-Phosphothreonine301 def: "Protein PB1_HUMAN with the residue 301 substituted with Phosphothreonine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0013428 name: PB1_HUMAN-Phosphoserine636 def: "Protein PB1_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0013429 name: PB1_HUMAN-Phosphoserine948 def: "Protein PB1_HUMAN with the residue 948 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0013430 name: PB1_HUMAN-Phosphoserine1453 def: "Protein PB1_HUMAN with the residue 1453 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0013431 name: PBX2_HUMAN-Phosphoserine105 def: "Protein PBX2_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:P40425] xref: UniProtKB:P40425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:B0013432 name: PCGF6_HUMAN-Phosphoserine30 def: "Protein PCGF6_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q9BYE7] xref: UniProtKB:Q9BYE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002111 ! PCGF6_HUMAN [Term] id: CCO:B0013433 name: PCNP_HUMAN-Phosphothreonine66 def: "Protein PCNP_HUMAN with the residue 66 substituted with Phosphothreonine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0013434 name: PCNP_HUMAN-Phosphoserine69 def: "Protein PCNP_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0013435 name: PCNP_HUMAN-Phosphoserine77 def: "Protein PCNP_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0013436 name: PCNP_HUMAN-Phosphothreonine139 def: "Protein PCNP_HUMAN with the residue 139 substituted with Phosphothreonine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0013437 name: PCNP_HUMAN-Phosphoserine142 def: "Protein PCNP_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0013438 name: PCNP_HUMAN-Phosphoserine147 def: "Protein PCNP_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0013439 name: PCNT_HUMAN-Phosphoserine1703 def: "Protein PCNT_HUMAN with the residue 1703 substituted with Phosphoserine" [UniProtKB:O95613] xref: UniProtKB:O95613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006078 ! PCNT_HUMAN [Term] id: CCO:B0013446 name: PCTK3_HUMAN-Phosphoserine12 def: "Protein PCTK3_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q07002] xref: UniProtKB:Q07002 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005295 ! PCTK3_HUMAN [Term] id: CCO:B0013447 name: PCTK3_HUMAN-Phosphoserine87 def: "Protein PCTK3_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q07002] xref: UniProtKB:Q07002 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005295 ! PCTK3_HUMAN [Term] id: CCO:B0013448 name: PCTK3_HUMAN-Phosphoserine130 def: "Protein PCTK3_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q07002] xref: UniProtKB:Q07002 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005295 ! PCTK3_HUMAN [Term] id: CCO:B0013449 name: PCTK3_HUMAN-Phosphoserine132 def: "Protein PCTK3_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q07002] comment: By similarity xref: UniProtKB:Q07002 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005295 ! PCTK3_HUMAN [Term] id: CCO:B0013450 name: PDCD4_HUMAN-Phosphoserine76 def: "Protein PDCD4_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q53EL6] xref: UniProtKB:Q53EL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001836 ! PDCD4_HUMAN [Term] id: CCO:B0013451 name: PDCD4_HUMAN-Phosphothreonine93 def: "Protein PDCD4_HUMAN with the residue 93 substituted with Phosphothreonine" [UniProtKB:Q53EL6] xref: UniProtKB:Q53EL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001836 ! PDCD4_HUMAN [Term] id: CCO:B0013452 name: PDCD4_HUMAN-Phosphotyrosine152 def: "Protein PDCD4_HUMAN with the residue 152 substituted with Phosphotyrosine" [UniProtKB:Q53EL6] xref: UniProtKB:Q53EL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001836 ! PDCD4_HUMAN [Term] id: CCO:B0013453 name: PDCD4_HUMAN-Phosphoserine457 def: "Protein PDCD4_HUMAN with the residue 457 substituted with Phosphoserine" [UniProtKB:Q53EL6] xref: UniProtKB:Q53EL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001836 ! PDCD4_HUMAN [Term] id: CCO:B0013454 name: PDCD5_HUMAN-Phosphoserine119 def: "Protein PDCD5_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:O14737] xref: UniProtKB:O14737 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006152 ! PDCD5_HUMAN [Term] id: CCO:B0013455 name: PDLI1_HUMAN-N-acetylthreonine2 def: "Protein PDLI1_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013456 name: PDLI1_HUMAN-Phosphoserine90 def: "Protein PDLI1_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013457 name: PDLI1_HUMAN-Phosphoserine130 def: "Protein PDLI1_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013458 name: PDLI1_HUMAN-Phosphotyrosine144 def: "Protein PDLI1_HUMAN with the residue 144 substituted with Phosphotyrosine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013459 name: PDLI1_HUMAN-Phosphotyrosine151 def: "Protein PDLI1_HUMAN with the residue 151 substituted with Phosphotyrosine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013460 name: PDLI1_HUMAN-Phosphoserine186 def: "Protein PDLI1_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013461 name: PDLI1_HUMAN-Phosphoserine187 def: "Protein PDLI1_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013462 name: PDLI1_HUMAN-Phosphoserine239 def: "Protein PDLI1_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013463 name: PDLI1_HUMAN-Phosphotyrosine321 def: "Protein PDLI1_HUMAN with the residue 321 substituted with Phosphotyrosine" [UniProtKB:O00151] xref: UniProtKB:O00151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:B0013464 name: PDLI5_HUMAN-N-acetylserine2 def: "Protein PDLI5_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013465 name: PDLI5_HUMAN-Phosphothreonine110 def: "Protein PDLI5_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013466 name: PDLI5_HUMAN-Phosphoserine111 def: "Protein PDLI5_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013467 name: PDLI5_HUMAN-Phosphoserine134 def: "Protein PDLI5_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013468 name: PDLI5_HUMAN-Phosphoserine136 def: "Protein PDLI5_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005715 ! actinin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013469 name: PDLI5_HUMAN-Phosphoserine137 def: "Protein PDLI5_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013470 name: PDLI5_HUMAN-Phosphoserine228 def: "Protein PDLI5_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q96HC4] comment: By similarity xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013471 name: PDLI5_HUMAN-Phosphotyrosine251 def: "Protein PDLI5_HUMAN with the residue 251 substituted with Phosphotyrosine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013472 name: PDLI5_HUMAN-Phosphoserine309 def: "Protein PDLI5_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013473 name: PDLI5_HUMAN-Phosphoserine313 def: "Protein PDLI5_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q96HC4] xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013474 name: PDLI5_HUMAN-Phosphoserine335 def: "Protein PDLI5_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q96HC4] comment: By similarity xref: UniProtKB:Q96HC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:B0013475 name: PDLI7_HUMAN-Phosphothreonine251 def: "Protein PDLI7_HUMAN with the residue 251 substituted with Phosphothreonine" [UniProtKB:Q9NR12] xref: UniProtKB:Q9NR12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005224 ! PDLI7_HUMAN [Term] id: CCO:B0013476 name: PDPK1_HUMAN-Phosphotyrosine9 def: "Protein PDPK1_HUMAN with the residue 9 substituted with Phosphotyrosine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013477 name: PDPK1_HUMAN-Phosphoserine25 def: "Protein PDPK1_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013478 name: PDPK1_HUMAN-Phosphoserine241 def: "Protein PDPK1_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:O15530] comment: by autocatalysis; xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001047 ! 3-phosphoinositide-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013479 name: PDPK1_HUMAN-Phosphothreonine245 def: "Protein PDPK1_HUMAN with the residue 245 substituted with Phosphothreonine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013480 name: PDPK1_HUMAN-Phosphotyrosine373 def: "Protein PDPK1_HUMAN with the residue 373 substituted with Phosphotyrosine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013481 name: PDPK1_HUMAN-Phosphotyrosine376 def: "Protein PDPK1_HUMAN with the residue 376 substituted with Phosphotyrosine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013482 name: PDPK1_HUMAN-Phosphoserine393 def: "Protein PDPK1_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013483 name: PDPK1_HUMAN-Phosphoserine396 def: "Protein PDPK1_HUMAN with the residue 396 substituted with Phosphoserine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013484 name: PDPK1_HUMAN-Phosphoserine410 def: "Protein PDPK1_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:O15530] xref: UniProtKB:O15530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:B0013485 name: PDS5A_HUMAN-Phosphothreonine1208 def: "Protein PDS5A_HUMAN with the residue 1208 substituted with Phosphothreonine" [UniProtKB:Q29RF7] xref: UniProtKB:Q29RF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001829 ! PDS5A_HUMAN [Term] id: CCO:B0013486 name: PDS5A_HUMAN-Phosphoserine1305 def: "Protein PDS5A_HUMAN with the residue 1305 substituted with Phosphoserine" [UniProtKB:Q29RF7] xref: UniProtKB:Q29RF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001829 ! PDS5A_HUMAN [Term] id: CCO:B0013487 name: PEX19_HUMAN-Phosphoserine35 def: "Protein PEX19_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:P40855] xref: UniProtKB:P40855 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005820 ! PEX19_HUMAN [Term] id: CCO:B0013488 name: PEX19_HUMAN-Phosphoserine54 def: "Protein PEX19_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:P40855] xref: UniProtKB:P40855 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005820 ! PEX19_HUMAN [Term] id: CCO:B0013489 name: PEX19_HUMAN-Phosphoserine146 def: "Protein PEX19_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:P40855] xref: UniProtKB:P40855 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005820 ! PEX19_HUMAN [Term] id: CCO:B0013490 name: PEX19_HUMAN-Phosphoserine147 def: "Protein PEX19_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:P40855] xref: UniProtKB:P40855 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005820 ! PEX19_HUMAN [Term] id: CCO:B0013491 name: PEX19_HUMAN-Phosphoserine149 def: "Protein PEX19_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:P40855] xref: UniProtKB:P40855 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005820 ! PEX19_HUMAN [Term] id: CCO:B0013492 name: PEX19_HUMAN-Phosphoserine177 def: "Protein PEX19_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:P40855] xref: UniProtKB:P40855 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005820 ! PEX19_HUMAN [Term] id: CCO:B0013493 name: PEX19_HUMAN-Phosphoserine184 def: "Protein PEX19_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:P40855] xref: UniProtKB:P40855 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005820 ! PEX19_HUMAN [Term] id: CCO:B0013494 name: PGAM1_HUMAN-N-acetylalanine2 def: "Protein PGAM1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P18669] xref: UniProtKB:P18669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006323 ! PGAM1_HUMAN [Term] id: CCO:B0013495 name: PGAM1_HUMAN-Phosphoserine14 def: "Protein PGAM1_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:P18669] comment: By similarity xref: UniProtKB:P18669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006323 ! PGAM1_HUMAN [Term] id: CCO:B0013496 name: PGAM1_HUMAN-Phosphotyrosine26 def: "Protein PGAM1_HUMAN with the residue 26 substituted with Phosphotyrosine" [UniProtKB:P18669] xref: UniProtKB:P18669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000557 ! bisphosphoglycerate mutase activity relationship: has_function CCO:F0000998 ! phosphoglycerate mutase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0003429 ! intramolecular transferase activity, phosphotransferases relationship: has_function CCO:F0008373 ! bisphosphoglycerate 2-phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0006323 ! PGAM1_HUMAN [Term] id: CCO:B0013497 name: PGAM1_HUMAN-Phosphoserine118 def: "Protein PGAM1_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:P18669] comment: By similarity xref: UniProtKB:P18669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006323 ! PGAM1_HUMAN [Term] id: CCO:B0013498 name: PGH2_HUMAN-Phosphoserine437 def: "Protein PGH2_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:P35354] comment: By similarity xref: UniProtKB:P35354 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001039 ! prostaglandin-endoperoxide synthase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0001593 ! PGH2_HUMAN [Term] id: CCO:B0013499 name: PGH2_HUMAN-Phosphotyrosine446 def: "Protein PGH2_HUMAN with the residue 446 substituted with Phosphotyrosine" [UniProtKB:P35354] comment: By similarity xref: UniProtKB:P35354 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001593 ! PGH2_HUMAN [Term] id: CCO:B0013500 name: PHB_HUMAN-Phosphoserine252 def: "Protein PHB_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:P35232] xref: UniProtKB:P35232 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001591 ! PHB_HUMAN [Term] id: CCO:B0013501 name: PHB_HUMAN-Phosphoserine254 def: "Protein PHB_HUMAN with the residue 254 substituted with Phosphoserine" [UniProtKB:P35232] xref: UniProtKB:P35232 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001591 ! PHB_HUMAN [Term] id: CCO:B0013502 name: PHC2_HUMAN-Phosphoserine701 def: "Protein PHC2_HUMAN with the residue 701 substituted with Phosphoserine" [UniProtKB:Q8IXK0] xref: UniProtKB:Q8IXK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005978 ! PHC2_HUMAN [Term] id: CCO:B0013503 name: PHC2_HUMAN-Phosphoserine704 def: "Protein PHC2_HUMAN with the residue 704 substituted with Phosphoserine" [UniProtKB:Q8IXK0] xref: UniProtKB:Q8IXK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005978 ! PHC2_HUMAN [Term] id: CCO:B0013504 name: PHC2_HUMAN-Phosphoserine733 def: "Protein PHC2_HUMAN with the residue 733 substituted with Phosphoserine" [UniProtKB:Q8IXK0] xref: UniProtKB:Q8IXK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005978 ! PHC2_HUMAN [Term] id: CCO:B0013505 name: PHC2_HUMAN-Phosphoserine745 def: "Protein PHC2_HUMAN with the residue 745 substituted with Phosphoserine" [UniProtKB:Q8IXK0] xref: UniProtKB:Q8IXK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005978 ! PHC2_HUMAN [Term] id: CCO:B0013506 name: PIAS1_HUMAN-Phosphoserine466 def: "Protein PIAS1_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:O75925] xref: UniProtKB:O75925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:B0013507 name: PIAS1_HUMAN-Phosphoserine467 def: "Protein PIAS1_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:O75925] xref: UniProtKB:O75925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:B0013508 name: PIAS1_HUMAN-Phosphoserine468 def: "Protein PIAS1_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:O75925] xref: UniProtKB:O75925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:B0013509 name: PIAS1_HUMAN-Phosphoserine483 def: "Protein PIAS1_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:O75925] comment: By similarity xref: UniProtKB:O75925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:B0013510 name: PIAS1_HUMAN-Phosphoserine485 def: "Protein PIAS1_HUMAN with the residue 485 substituted with Phosphoserine" [UniProtKB:O75925] comment: By similarity xref: UniProtKB:O75925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:B0013511 name: PIAS1_HUMAN-Phosphothreonine487 def: "Protein PIAS1_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:O75925] comment: By similarity xref: UniProtKB:O75925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:B0013512 name: PIM2_HUMAN-Phosphothreonine195 def: "Protein PIM2_HUMAN with the residue 195 substituted with Phosphothreonine" [UniProtKB:Q9P1W9] xref: UniProtKB:Q9P1W9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002185 ! PIM2_HUMAN [Term] id: CCO:B0013513 name: PIM2_HUMAN-Phosphoserine204 def: "Protein PIM2_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:Q9P1W9] xref: UniProtKB:Q9P1W9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002185 ! PIM2_HUMAN [Term] id: CCO:B0013514 name: PIN1_HUMAN-Phosphoserine108 def: "Protein PIN1_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q13526] xref: UniProtKB:Q13526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001755 ! PIN1_HUMAN [Term] id: CCO:B0013515 name: PININ_HUMAN-N-acetylalanine2 def: "Protein PININ_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013516 name: PININ_HUMAN-Phosphoserine66 def: "Protein PININ_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013517 name: PININ_HUMAN-Phosphoserine96 def: "Protein PININ_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000820 ! nuclear speck relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013518 name: PININ_HUMAN-Phosphoserine100 def: "Protein PININ_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013519 name: PININ_HUMAN-Phosphoserine114 def: "Protein PININ_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013520 name: PININ_HUMAN-Phosphoserine347 def: "Protein PININ_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013521 name: PININ_HUMAN-Phosphoserine381 def: "Protein PININ_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013522 name: PININ_HUMAN-Phosphoserine441 def: "Protein PININ_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:Q9H307] comment: By similarity xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013523 name: PININ_HUMAN-Phosphoserine443 def: "Protein PININ_HUMAN with the residue 443 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013524 name: PININ_HUMAN-Phosphoserine649 def: "Protein PININ_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013525 name: PININ_HUMAN-Phosphoserine658 def: "Protein PININ_HUMAN with the residue 658 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013526 name: PININ_HUMAN-Phosphoserine663 def: "Protein PININ_HUMAN with the residue 663 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013527 name: PININ_HUMAN-Phosphoserine666 def: "Protein PININ_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013528 name: PININ_HUMAN-Phosphoserine667 def: "Protein PININ_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013529 name: PININ_HUMAN-Phosphoserine671 def: "Protein PININ_HUMAN with the residue 671 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013530 name: PININ_HUMAN-Phosphoserine672 def: "Protein PININ_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013531 name: PININ_HUMAN-Phosphoserine690 def: "Protein PININ_HUMAN with the residue 690 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013532 name: PININ_HUMAN-Phosphoserine692 def: "Protein PININ_HUMAN with the residue 692 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013533 name: PININ_HUMAN-Phosphoserine695 def: "Protein PININ_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0013534 name: PKCB1_HUMAN-Phosphoserine486 def: "Protein PKCB1_HUMAN with the residue 486 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0013535 name: PKCB1_HUMAN-Phosphoserine490 def: "Protein PKCB1_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0013536 name: PKCB1_HUMAN-Phosphoserine547 def: "Protein PKCB1_HUMAN with the residue 547 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0013537 name: PKCB1_HUMAN-Phosphoserine652 def: "Protein PKCB1_HUMAN with the residue 652 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0013538 name: PKCB1_HUMAN-Phosphoserine668 def: "Protein PKCB1_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0013539 name: PKCB1_HUMAN-Phosphoserine1086 def: "Protein PKCB1_HUMAN with the residue 1086 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0013540 name: PKD2_HUMAN-Phosphoserine166 def: "Protein PKD2_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q13563] xref: UniProtKB:Q13563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001757 ! PKD2_HUMAN [Term] id: CCO:B0013541 name: PKD2_HUMAN-Phosphoserine254 def: "Protein PKD2_HUMAN with the residue 254 substituted with Phosphoserine" [UniProtKB:Q13563] xref: UniProtKB:Q13563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001515 ! voltage-gated chloride channel activity relationship: has_function CCO:F0001516 ! voltage-gated sodium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000484 ! basal body relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001757 ! PKD2_HUMAN [Term] id: CCO:B0013542 name: PKD2_HUMAN-Phosphothreonine260 def: "Protein PKD2_HUMAN with the residue 260 substituted with Phosphothreonine" [UniProtKB:Q13563] xref: UniProtKB:Q13563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001757 ! PKD2_HUMAN [Term] id: CCO:B0013543 name: PKD2_HUMAN-Phosphoserine263 def: "Protein PKD2_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q13563] xref: UniProtKB:Q13563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001757 ! PKD2_HUMAN [Term] id: CCO:B0013544 name: PKD2_HUMAN-Phosphoserine852 def: "Protein PKD2_HUMAN with the residue 852 substituted with Phosphoserine" [UniProtKB:Q13563] xref: UniProtKB:Q13563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001757 ! PKD2_HUMAN [Term] id: CCO:B0013545 name: PKD2_HUMAN-Phosphoserine858 def: "Protein PKD2_HUMAN with the residue 858 substituted with Phosphoserine" [UniProtKB:Q13563] xref: UniProtKB:Q13563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001757 ! PKD2_HUMAN [Term] id: CCO:B0013546 name: PKHF2_HUMAN-Phosphoserine239 def: "Protein PKHF2_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q9H8W4] xref: UniProtKB:Q9H8W4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005194 ! PKHF2_HUMAN [Term] id: CCO:B0013547 name: PKN1_HUMAN-Phosphoserine376 def: "Protein PKN1_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q16512] xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0013548 name: PKN1_HUMAN-Phosphoserine562 def: "Protein PKN1_HUMAN with the residue 562 substituted with Phosphoserine" [UniProtKB:Q16512] xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0013549 name: PKN1_HUMAN-Phosphothreonine774 def: "Protein PKN1_HUMAN with the residue 774 substituted with Phosphothreonine" [UniProtKB:Q16512] comment: Probable xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0013550 name: PKN1_HUMAN-Phosphoserine916 def: "Protein PKN1_HUMAN with the residue 916 substituted with Phosphoserine" [UniProtKB:Q16512] xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0013551 name: PKP2_HUMAN-Phosphoserine132 def: "Protein PKP2_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0013552 name: PKP2_HUMAN-Phosphoserine169 def: "Protein PKP2_HUMAN with the residue 169 substituted with Phosphoserine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0013553 name: PLAK_HUMAN-Phosphotyrosine20 def: "Protein PLAK_HUMAN with the residue 20 substituted with Phosphotyrosine" [UniProtKB:P14923] xref: UniProtKB:P14923 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:B0013554 name: PLAK_HUMAN-Phosphoserine182 def: "Protein PLAK_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:P14923] xref: UniProtKB:P14923 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:B0013556 name: PLCB1_HUMAN-Phosphothreonine333 def: "Protein PLCB1_HUMAN with the residue 333 substituted with Phosphothreonine" [UniProtKB:Q9NQ66] comment: By similarity xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013557 name: PLCB1_HUMAN-Phosphotyrosine334 def: "Protein PLCB1_HUMAN with the residue 334 substituted with Phosphotyrosine" [UniProtKB:Q9NQ66] comment: By similarity xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013558 name: PLCB1_HUMAN-Phosphothreonine336 def: "Protein PLCB1_HUMAN with the residue 336 substituted with Phosphothreonine" [UniProtKB:Q9NQ66] comment: By similarity xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013559 name: PLCB1_HUMAN-Phosphoserine569 def: "Protein PLCB1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q9NQ66] xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013560 name: PLCB1_HUMAN-Phosphothreonine573 def: "Protein PLCB1_HUMAN with the residue 573 substituted with Phosphothreonine" [UniProtKB:Q9NQ66] xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013561 name: PLCB1_HUMAN-Phosphoserine887 def: "Protein PLCB1_HUMAN with the residue 887 substituted with Phosphoserine" [UniProtKB:Q9NQ66] comment: by PKC; By similarity xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013562 name: PLCB1_HUMAN-N6-acetyllysine972 def: "Protein PLCB1_HUMAN with the residue 972 substituted with N6-acetyllysine" [UniProtKB:Q9NQ66] xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013563 name: PLCB1_HUMAN-N6-acetyllysine976 def: "Protein PLCB1_HUMAN with the residue 976 substituted with N6-acetyllysine" [UniProtKB:Q9NQ66] xref: UniProtKB:Q9NQ66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0002151 ! PLCB1_HUMAN [Term] id: CCO:B0013564 name: PLCG1_HUMAN-Phosphotyrosine771 def: "Protein PLCG1_HUMAN with the residue 771 substituted with Phosphotyrosine" [UniProtKB:P19174] xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0013565 name: PLCG1_HUMAN-Phosphotyrosine775 def: "Protein PLCG1_HUMAN with the residue 775 substituted with Phosphotyrosine" [UniProtKB:P19174] xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0013566 name: PLCG1_HUMAN-Phosphotyrosine783 def: "Protein PLCG1_HUMAN with the residue 783 substituted with Phosphotyrosine" [UniProtKB:P19174] xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0013567 name: PLCG1_HUMAN-Phosphotyrosine1253 def: "Protein PLCG1_HUMAN with the residue 1253 substituted with Phosphotyrosine" [UniProtKB:P19174] xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0013568 name: PLK1_HUMAN-Phosphoserine137 def: "Protein PLK1_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:P53350] comment: Probable xref: UniProtKB:P53350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:B0013569 name: PLK1_HUMAN-Phosphothreonine210 def: "Protein PLK1_HUMAN with the residue 210 substituted with Phosphothreonine" [UniProtKB:P53350] xref: UniProtKB:P53350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:B0013570 name: PLK1_HUMAN-Phosphoserine269 def: "Protein PLK1_HUMAN with the residue 269 substituted with Phosphoserine" [UniProtKB:P53350] comment: by autocatalysis; By similarity xref: UniProtKB:P53350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:B0013571 name: PLK1_HUMAN-Phosphoserine335 def: "Protein PLK1_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:P53350] xref: UniProtKB:P53350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:B0013572 name: PML_HUMAN-Phosphoserine8 def: "Protein PML_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013573 name: PML_HUMAN-Phosphoserine403 def: "Protein PML_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013574 name: PML_HUMAN-Phosphoserine504 def: "Protein PML_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:P29590] comment: By similarity xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013575 name: PML_HUMAN-Phosphoserine505 def: "Protein PML_HUMAN with the residue 505 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013576 name: PML_HUMAN-Phosphoserine512 def: "Protein PML_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013577 name: PML_HUMAN-Phosphoserine518 def: "Protein PML_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013578 name: PML_HUMAN-Phosphoserine527 def: "Protein PML_HUMAN with the residue 527 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013579 name: PML_HUMAN-Phosphoserine530 def: "Protein PML_HUMAN with the residue 530 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013580 name: PML_HUMAN-Phosphoserine535 def: "Protein PML_HUMAN with the residue 535 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013581 name: PML_HUMAN-Phosphoserine560 def: "Protein PML_HUMAN with the residue 560 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013582 name: PML_HUMAN-Phosphoserine561 def: "Protein PML_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013583 name: PML_HUMAN-Phosphoserine562 def: "Protein PML_HUMAN with the residue 562 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013584 name: PML_HUMAN-Phosphoserine565 def: "Protein PML_HUMAN with the residue 565 substituted with Phosphoserine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0013585 name: PMS2_HUMAN-Phosphotyrosine181 def: "Protein PMS2_HUMAN with the residue 181 substituted with Phosphotyrosine" [UniProtKB:P54278] comment: By similarity xref: UniProtKB:P54278 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001669 ! PMS2_HUMAN [Term] id: CCO:B0013586 name: PMS2_HUMAN-Phosphoserine403 def: "Protein PMS2_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:P54278] xref: UniProtKB:P54278 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001669 ! PMS2_HUMAN [Term] id: CCO:B0013587 name: PMS2_HUMAN-Phosphothreonine573 def: "Protein PMS2_HUMAN with the residue 573 substituted with Phosphothreonine" [UniProtKB:P54278] xref: UniProtKB:P54278 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_function CCO:F0004954 ! single base insertion or deletion binding relationship: has_function CCO:F0004987 ! MutSalpha complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001669 ! PMS2_HUMAN [Term] id: CCO:B0013588 name: PMYT1_HUMAN-Phosphoserine94 def: "Protein PMYT1_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q99640] xref: UniProtKB:Q99640 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:B0013589 name: PMYT1_HUMAN-Phosphoserine143 def: "Protein PMYT1_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q99640] xref: UniProtKB:Q99640 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:B0013590 name: PMYT1_HUMAN-Phosphoserine426 def: "Protein PMYT1_HUMAN with the residue 426 substituted with Phosphoserine" [UniProtKB:Q99640] comment: by PLK1; xref: UniProtKB:Q99640 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:B0013591 name: PMYT1_HUMAN-Phosphothreonine495 def: "Protein PMYT1_HUMAN with the residue 495 substituted with Phosphothreonine" [UniProtKB:Q99640] comment: by PLK1; xref: UniProtKB:Q99640 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:B0013592 name: PNPH_HUMAN-N-acetylmethionine1 def: "Protein PNPH_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P00491] xref: UniProtKB:P00491 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006097 ! PNPH_HUMAN [Term] id: CCO:B0013593 name: PO2F1_HUMAN-Phosphoserine448 def: "Protein PO2F1_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:P14859] xref: UniProtKB:P14859 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006069 ! PO2F1_HUMAN [Term] id: CCO:B0013594 name: PP1B_HUMAN-N-acetylalanine2 def: "Protein PP1B_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62140] xref: UniProtKB:P62140 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001689 ! PP1B_HUMAN [Term] id: CCO:B0013595 name: PP1B_HUMAN-Phosphoserine41 def: "Protein PP1B_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:P62140] xref: UniProtKB:P62140 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001689 ! PP1B_HUMAN [Term] id: CCO:B0013596 name: PP1B_HUMAN-Phosphoserine47 def: "Protein PP1B_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:P62140] xref: UniProtKB:P62140 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001689 ! PP1B_HUMAN [Term] id: CCO:B0013597 name: PP2AA_HUMAN-Phosphotyrosine307 def: "Protein PP2AA_HUMAN with the residue 307 substituted with Phosphotyrosine" [UniProtKB:P67775] xref: UniProtKB:P67775 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001697 ! PP2AA_HUMAN [Term] id: CCO:B0013598 name: PP2AA_HUMAN-Leucine methyl ester309 def: "Protein PP2AA_HUMAN with the residue 309 substituted with Leucine methyl ester" [UniProtKB:P67775] xref: UniProtKB:P67775 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001697 ! PP2AA_HUMAN [Term] id: CCO:B0013599 name: PPARG_HUMAN-Phosphoserine112 def: "Protein PPARG_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:P37231] comment: by MAPK; By similarity xref: UniProtKB:P37231 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005616 ! PPARG_HUMAN [Term] id: CCO:B0013600 name: PPIA_HUMAN-N-acetylvaline2 def: "Protein PPIA_HUMAN with the residue 2 substituted with N-acetylvaline" [UniProtKB:P62937] comment: partial; xref: UniProtKB:P62937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006072 ! PPIA_HUMAN [Term] id: CCO:B0013601 name: PPIA_HUMAN-Phosphoserine21 def: "Protein PPIA_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P62937] comment: By similarity xref: UniProtKB:P62937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0005639 ! peptide binding relationship: has_function CCO:F0006246 ! virion binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0006072 ! PPIA_HUMAN [Term] id: CCO:B0013602 name: PPIA_HUMAN-N6-acetyllysine125 def: "Protein PPIA_HUMAN with the residue 125 substituted with N6-acetyllysine" [UniProtKB:P62937] xref: UniProtKB:P62937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006072 ! PPIA_HUMAN [Term] id: CCO:B0013603 name: PPIA_HUMAN-Phosphothreonine157 def: "Protein PPIA_HUMAN with the residue 157 substituted with Phosphothreonine" [UniProtKB:P62937] xref: UniProtKB:P62937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006072 ! PPIA_HUMAN [Term] id: CCO:B0013604 name: PPM1A_HUMAN-Phosphoserine377 def: "Protein PPM1A_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:P35813] comment: By similarity xref: UniProtKB:P35813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000541 ! protein serine/threonine phosphatase complex relationship: transformation_of CCO:B0005649 ! PPM1A_HUMAN [Term] id: CCO:B0013605 name: PPM1G_HUMAN-Phosphoserine183 def: "Protein PPM1G_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:O15355] xref: UniProtKB:O15355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001375 ! PPM1G_HUMAN [Term] id: CCO:B0013606 name: PPM1G_HUMAN-Phosphoserine527 def: "Protein PPM1G_HUMAN with the residue 527 substituted with Phosphoserine" [UniProtKB:O15355] xref: UniProtKB:O15355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000541 ! protein serine/threonine phosphatase complex relationship: transformation_of CCO:B0001375 ! PPM1G_HUMAN [Term] id: CCO:B0013607 name: PR285_HUMAN-Phosphoserine338 def: "Protein PR285_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:Q9BYK8] xref: UniProtKB:Q9BYK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006035 ! PR285_HUMAN [Term] id: CCO:B0013608 name: PRC1_HUMAN-Phosphoserine195 def: "Protein PRC1_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:O43663] xref: UniProtKB:O43663 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001394 ! PRC1_HUMAN [Term] id: CCO:B0013609 name: PRC1_HUMAN-Phosphothreonine470 def: "Protein PRC1_HUMAN with the residue 470 substituted with Phosphothreonine" [UniProtKB:O43663] comment: by CDK2; in vitro; xref: UniProtKB:O43663 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001394 ! PRC1_HUMAN [Term] id: CCO:B0013610 name: PRC1_HUMAN-Phosphothreonine481 def: "Protein PRC1_HUMAN with the residue 481 substituted with Phosphothreonine" [UniProtKB:O43663] xref: UniProtKB:O43663 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000436 ! spindle microtubule relationship: transformation_of CCO:B0001394 ! PRC1_HUMAN [Term] id: CCO:B0013611 name: PRC1_HUMAN-Phosphoserine592 def: "Protein PRC1_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:O43663] xref: UniProtKB:O43663 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001394 ! PRC1_HUMAN [Term] id: CCO:B0013612 name: PRI2_HUMAN-Phosphotyrosine381 def: "Protein PRI2_HUMAN with the residue 381 substituted with Phosphotyrosine" [UniProtKB:P49643] xref: UniProtKB:P49643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000407 ! DNA primase activity relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008141 ! 4 iron, 4 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000266 ! alpha DNA polymerase:primase complex relationship: transformation_of CCO:B0005508 ! PRI2_HUMAN [Term] id: CCO:B0013613 name: PROF1_HUMAN-N-acetylalanine2 def: "Protein PROF1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P07737] xref: UniProtKB:P07737 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0006154 ! PROF1_HUMAN [Term] id: CCO:B0013614 name: PROF1_HUMAN-N6-acetyllysine105 def: "Protein PROF1_HUMAN with the residue 105 substituted with N6-acetyllysine" [UniProtKB:P07737] xref: UniProtKB:P07737 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006154 ! PROF1_HUMAN [Term] id: CCO:B0013615 name: PROF1_HUMAN-Phosphotyrosine129 def: "Protein PROF1_HUMAN with the residue 129 substituted with Phosphotyrosine" [UniProtKB:P07737] xref: UniProtKB:P07737 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006154 ! PROF1_HUMAN [Term] id: CCO:B0013616 name: PROF2_HUMAN-N-acetylalanine2 def: "Protein PROF2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P35080] comment: By similarity xref: UniProtKB:P35080 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:B0013617 name: PRS4_HUMAN-Phosphotyrosine439 def: "Protein PRS4_HUMAN with the residue 439 substituted with Phosphotyrosine" [UniProtKB:P62191] xref: UniProtKB:P62191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: transformation_of CCO:B0005314 ! PRS4_HUMAN [Term] id: CCO:B0013618 name: PSA1_HUMAN-N-acetylmethionine1 def: "Protein PSA1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P25786] xref: UniProtKB:P25786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005233 ! PSA1_HUMAN [Term] id: CCO:B0013619 name: PSA3_HUMAN-N-acetylserine2 def: "Protein PSA3_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P25788] xref: UniProtKB:P25788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:B0013620 name: PSA3_HUMAN-Phosphotyrosine161 def: "Protein PSA3_HUMAN with the residue 161 substituted with Phosphotyrosine" [UniProtKB:P25788] xref: UniProtKB:P25788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: transformation_of CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:B0013621 name: PSA3_HUMAN-Phosphoserine243 def: "Protein PSA3_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:P25788] xref: UniProtKB:P25788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:B0013622 name: PSA3_HUMAN-Phosphoserine250 def: "Protein PSA3_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:P25788] xref: UniProtKB:P25788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:B0013623 name: PSD11_HUMAN-N-acetylalanine2 def: "Protein PSD11_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O00231] xref: UniProtKB:O00231 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:B0013624 name: PSD11_HUMAN-Phosphoserine14 def: "Protein PSD11_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:O00231] xref: UniProtKB:O00231 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:B0013625 name: PSD11_HUMAN-Phosphoserine79 def: "Protein PSD11_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:O00231] xref: UniProtKB:O00231 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:B0013626 name: PSD11_HUMAN-Phosphoserine272 def: "Protein PSD11_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:O00231] xref: UniProtKB:O00231 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:B0013627 name: PSMD1_HUMAN-N-acetylmethionine1 def: "Protein PSMD1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q99460] comment: partial; xref: UniProtKB:Q99460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002066 ! PSMD1_HUMAN [Term] id: CCO:B0013628 name: PSMD1_HUMAN-Phosphotyrosine49 def: "Protein PSMD1_HUMAN with the residue 49 substituted with Phosphotyrosine" [UniProtKB:Q99460] xref: UniProtKB:Q99460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002066 ! PSMD1_HUMAN [Term] id: CCO:B0013629 name: PSMD1_HUMAN-Phosphothreonine273 def: "Protein PSMD1_HUMAN with the residue 273 substituted with Phosphothreonine" [UniProtKB:Q99460] xref: UniProtKB:Q99460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002066 ! PSMD1_HUMAN [Term] id: CCO:B0013630 name: PSMD1_HUMAN-Phosphothreonine311 def: "Protein PSMD1_HUMAN with the residue 311 substituted with Phosphothreonine" [UniProtKB:Q99460] xref: UniProtKB:Q99460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002066 ! PSMD1_HUMAN [Term] id: CCO:B0013631 name: PSMD1_HUMAN-Phosphoserine315 def: "Protein PSMD1_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q99460] xref: UniProtKB:Q99460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002066 ! PSMD1_HUMAN [Term] id: CCO:B0013632 name: PSMD2_HUMAN-N-acetylmethionine1 def: "Protein PSMD2_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q13200] xref: UniProtKB:Q13200 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001745 ! PSMD2_HUMAN [Term] id: CCO:B0013633 name: PSMD2_HUMAN-Phosphoserine16 def: "Protein PSMD2_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q13200] xref: UniProtKB:Q13200 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001745 ! PSMD2_HUMAN [Term] id: CCO:B0013634 name: PSMD2_HUMAN-Phosphothreonine90 def: "Protein PSMD2_HUMAN with the residue 90 substituted with Phosphothreonine" [UniProtKB:Q13200] xref: UniProtKB:Q13200 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001745 ! PSMD2_HUMAN [Term] id: CCO:B0013635 name: PSMD2_HUMAN-Phosphoserine361 def: "Protein PSMD2_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q13200] xref: UniProtKB:Q13200 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001745 ! PSMD2_HUMAN [Term] id: CCO:B0013636 name: PSN1_HUMAN-Phosphoserine43 def: "Protein PSN1_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:P49768] xref: UniProtKB:P49768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:B0013637 name: PSN1_HUMAN-Phosphoserine310 def: "Protein PSN1_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:P49768] comment: by PKA; xref: UniProtKB:P49768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:B0013638 name: PSN1_HUMAN-Phosphoserine346 def: "Protein PSN1_HUMAN with the residue 346 substituted with Phosphoserine" [UniProtKB:P49768] comment: by PKC; xref: UniProtKB:P49768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000256 ! integral to nuclear inner membrane relationship: located_in CCO:C0000257 ! nuclear outer membrane relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:B0013639 name: PSN1_HUMAN-Phosphoserine367 def: "Protein PSN1_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:P49768] comment: By similarity xref: UniProtKB:P49768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:B0013640 name: PTEN_HUMAN-Phosphothreonine366 def: "Protein PTEN_HUMAN with the residue 366 substituted with Phosphothreonine" [UniProtKB:P60484] xref: UniProtKB:P60484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001685 ! PTEN_HUMAN [Term] id: CCO:B0013641 name: PTEN_HUMAN-Phosphoserine370 def: "Protein PTEN_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:P60484] comment: by CK2; xref: UniProtKB:P60484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000842 ! phosphatidylinositol-3-phosphatase activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003120 ! phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_function CCO:F0008158 ! inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity relationship: has_function CCO:F0008197 ! phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001685 ! PTEN_HUMAN [Term] id: CCO:B0013642 name: PTEN_HUMAN-Phosphoserine385 def: "Protein PTEN_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:P60484] comment: by CK2; xref: UniProtKB:P60484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001685 ! PTEN_HUMAN [Term] id: CCO:B0013643 name: PTEN_HUMAN-Phosphothreonine401 def: "Protein PTEN_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:P60484] xref: UniProtKB:P60484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001685 ! PTEN_HUMAN [Term] id: CCO:B0013649 name: PTMS_HUMAN-N-acetylserine2 def: "Protein PTMS_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P20962] comment: By similarity xref: UniProtKB:P20962 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001539 ! PTMS_HUMAN [Term] id: CCO:B0013650 name: PTTG1_HUMAN-Phosphoserine165 def: "Protein PTTG1_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:O95997] comment: by CDC2; xref: UniProtKB:O95997 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001457 ! PTTG1_HUMAN [Term] id: CCO:B0013651 name: PYGO2_HUMAN-Phosphoserine97 def: "Protein PYGO2_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q9BRQ0] xref: UniProtKB:Q9BRQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006062 ! PYGO2_HUMAN [Term] id: CCO:B0013652 name: PYGO2_HUMAN-Phosphothreonine302 def: "Protein PYGO2_HUMAN with the residue 302 substituted with Phosphothreonine" [UniProtKB:Q9BRQ0] xref: UniProtKB:Q9BRQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006062 ! PYGO2_HUMAN [Term] id: CCO:B0013653 name: QN1_HUMAN-Phosphoserine770 def: "Protein QN1_HUMAN with the residue 770 substituted with Phosphoserine" [UniProtKB:Q5TB80] xref: UniProtKB:Q5TB80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001883 ! QN1_HUMAN [Term] id: CCO:B0013654 name: QN1_HUMAN-Phosphoserine776 def: "Protein QN1_HUMAN with the residue 776 substituted with Phosphoserine" [UniProtKB:Q5TB80] xref: UniProtKB:Q5TB80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: transformation_of CCO:B0001883 ! QN1_HUMAN [Term] id: CCO:B0013655 name: RAB1A_HUMAN-N-acetylserine2 def: "Protein RAB1A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62820] xref: UniProtKB:P62820 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006222 ! RAB1A_HUMAN [Term] id: CCO:B0013656 name: RAB1A_HUMAN-Phosphoserine194 def: "Protein RAB1A_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:P62820] comment: by CDC2; Probable xref: UniProtKB:P62820 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006222 ! RAB1A_HUMAN [Term] id: CCO:B0013657 name: RAB4A_HUMAN-Phosphoserine199 def: "Protein RAB4A_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:P20338] comment: by CDC2; xref: UniProtKB:P20338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006295 ! RAB4A_HUMAN [Term] id: CCO:B0013658 name: RAB4A_HUMAN-Cysteine methyl ester213 def: "Protein RAB4A_HUMAN with the residue 213 substituted with Cysteine methyl ester" [UniProtKB:P20338] comment: By similarity xref: UniProtKB:P20338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006295 ! RAB4A_HUMAN [Term] id: CCO:B0013659 name: RAC1_HUMAN-ADP-ribosylasparagine39 def: "Protein RAC1_HUMAN with the residue 39 substituted with ADP-ribosylasparagine" [UniProtKB:P63000] comment: by botulinum toxin; By similarity xref: UniProtKB:P63000 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:B0013660 name: RAC1_HUMAN-Cysteine methyl ester189 def: "Protein RAC1_HUMAN with the residue 189 substituted with Cysteine methyl ester" [UniProtKB:P63000] xref: UniProtKB:P63000 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:B0013661 name: RAD17_HUMAN-Phosphothreonine55 def: "Protein RAD17_HUMAN with the residue 55 substituted with Phosphothreonine" [UniProtKB:O75943] comment: By similarity xref: UniProtKB:O75943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001441 ! RAD17_HUMAN [Term] id: CCO:B0013662 name: RAD17_HUMAN-Phosphothreonine304 def: "Protein RAD17_HUMAN with the residue 304 substituted with Phosphothreonine" [UniProtKB:O75943] xref: UniProtKB:O75943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001441 ! RAD17_HUMAN [Term] id: CCO:B0013663 name: RAD17_HUMAN-Phosphoserine646 def: "Protein RAD17_HUMAN with the residue 646 substituted with Phosphoserine" [UniProtKB:O75943] comment: by ATR and ATM; xref: UniProtKB:O75943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001441 ! RAD17_HUMAN [Term] id: CCO:B0013664 name: RAD17_HUMAN-Phosphoserine656 def: "Protein RAD17_HUMAN with the residue 656 substituted with Phosphoserine" [UniProtKB:O75943] comment: by ATR and ATM; xref: UniProtKB:O75943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001441 ! RAD17_HUMAN [Term] id: CCO:B0013665 name: RAD50_HUMAN-Phosphoserine237 def: "Protein RAD50_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q92878] comment: By similarity xref: UniProtKB:Q92878 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002021 ! RAD50_HUMAN [Term] id: CCO:B0013666 name: RAD50_HUMAN-Phosphoserine635 def: "Protein RAD50_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:Q92878] xref: UniProtKB:Q92878 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002021 ! RAD50_HUMAN [Term] id: CCO:B0013667 name: RAD50_HUMAN-Phosphoserine640 def: "Protein RAD50_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q92878] xref: UniProtKB:Q92878 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002021 ! RAD50_HUMAN [Term] id: CCO:B0013668 name: RAD50_HUMAN-Phosphothreonine690 def: "Protein RAD50_HUMAN with the residue 690 substituted with Phosphothreonine" [UniProtKB:Q92878] xref: UniProtKB:Q92878 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002021 ! RAD50_HUMAN [Term] id: CCO:B0013669 name: RAD51_HUMAN-Phosphothreonine309 def: "Protein RAD51_HUMAN with the residue 309 substituted with Phosphothreonine" [UniProtKB:Q06609] comment: by CHK1; xref: UniProtKB:Q06609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:B0013670 name: RAD52_HUMAN-Phosphothreonine318 def: "Protein RAD52_HUMAN with the residue 318 substituted with Phosphothreonine" [UniProtKB:P43351] xref: UniProtKB:P43351 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001621 ! RAD52_HUMAN [Term] id: CCO:B0013671 name: RAD9A_HUMAN-Phosphotyrosine28 def: "Protein RAD9A_HUMAN with the residue 28 substituted with Phosphotyrosine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013672 name: RAD9A_HUMAN-Phosphoserine272 def: "Protein RAD9A_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013673 name: RAD9A_HUMAN-Phosphoserine277 def: "Protein RAD9A_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013674 name: RAD9A_HUMAN-Phosphoserine328 def: "Protein RAD9A_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0002192 ! exodeoxyribonuclease III activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013675 name: RAD9A_HUMAN-Phosphoserine341 def: "Protein RAD9A_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013676 name: RAD9A_HUMAN-Phosphoserine375 def: "Protein RAD9A_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013677 name: RAD9A_HUMAN-Phosphoserine380 def: "Protein RAD9A_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013678 name: RAD9A_HUMAN-Phosphoserine387 def: "Protein RAD9A_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q99638] xref: UniProtKB:Q99638 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002077 ! RAD9A_HUMAN [Term] id: CCO:B0013679 name: RAF1_HUMAN-Phosphoserine43 def: "Protein RAF1_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:P04049] xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013680 name: RAF1_HUMAN-Phosphoserine252 def: "Protein RAF1_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:P04049] xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013681 name: RAF1_HUMAN-Phosphoserine259 def: "Protein RAF1_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:P04049] comment: by PKC; xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013682 name: RAF1_HUMAN-Phosphothreonine268 def: "Protein RAF1_HUMAN with the residue 268 substituted with Phosphothreonine" [UniProtKB:P04049] comment: by autocatalysis; xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013683 name: RAF1_HUMAN-Phosphoserine294 def: "Protein RAF1_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:P04049] xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013684 name: RAF1_HUMAN-Phosphoserine301 def: "Protein RAF1_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:P04049] xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013685 name: RAF1_HUMAN-Phosphoserine338 def: "Protein RAF1_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:P04049] comment: by PAK2 and PAK3; xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013686 name: RAF1_HUMAN-Phosphoserine499 def: "Protein RAF1_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:P04049] comment: by PKC; xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013687 name: RAF1_HUMAN-Phosphoserine621 def: "Protein RAF1_HUMAN with the residue 621 substituted with Phosphoserine" [UniProtKB:P04049] xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0013688 name: RAI1_HUMAN-Phosphoserine568 def: "Protein RAI1_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0013689 name: RAI1_HUMAN-Phosphoserine571 def: "Protein RAI1_HUMAN with the residue 571 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0013690 name: RAI1_HUMAN-Phosphoserine574 def: "Protein RAI1_HUMAN with the residue 574 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0013691 name: RAI1_HUMAN-Phosphothreonine1476 def: "Protein RAI1_HUMAN with the residue 1476 substituted with Phosphothreonine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0013692 name: RANB3_HUMAN-Phosphoserine96 def: "Protein RANB3_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013693 name: RANB3_HUMAN-Phosphoserine100 def: "Protein RANB3_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013694 name: RANB3_HUMAN-Phosphoserine101 def: "Protein RANB3_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013695 name: RANB3_HUMAN-Phosphoserine108 def: "Protein RANB3_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013696 name: RANB3_HUMAN-Phosphotyrosine115 def: "Protein RANB3_HUMAN with the residue 115 substituted with Phosphotyrosine" [UniProtKB:Q9H6Z4] comment: By similarity xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013697 name: RANB3_HUMAN-Phosphoserine126 def: "Protein RANB3_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013698 name: RANB3_HUMAN-Phosphoserine133 def: "Protein RANB3_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013699 name: RANB3_HUMAN-Phosphoserine221 def: "Protein RANB3_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] comment: By similarity xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013700 name: RANB3_HUMAN-Phosphoserine359 def: "Protein RANB3_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0013701 name: RANG_HUMAN-Phosphothreonine13 def: "Protein RANG_HUMAN with the residue 13 substituted with Phosphothreonine" [UniProtKB:P43487] xref: UniProtKB:P43487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:B0013702 name: RANG_HUMAN-Phosphoserine14 def: "Protein RANG_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:P43487] xref: UniProtKB:P43487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:B0013703 name: RANG_HUMAN-Phosphothreonine15 def: "Protein RANG_HUMAN with the residue 15 substituted with Phosphothreonine" [UniProtKB:P43487] xref: UniProtKB:P43487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:B0013704 name: RANG_HUMAN-Phosphothreonine18 def: "Protein RANG_HUMAN with the residue 18 substituted with Phosphothreonine" [UniProtKB:P43487] xref: UniProtKB:P43487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:B0013705 name: RANG_HUMAN-Phosphoserine21 def: "Protein RANG_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P43487] xref: UniProtKB:P43487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:B0013706 name: RANG_HUMAN-Phosphoserine60 def: "Protein RANG_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:P43487] comment: By similarity xref: UniProtKB:P43487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:B0013707 name: RAN_HUMAN-N-acetylalanine2 def: "Protein RAN_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62826] xref: UniProtKB:P62826 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0001693 ! RAN_HUMAN [Term] id: CCO:B0013708 name: RAN_HUMAN-Phosphotyrosine147 def: "Protein RAN_HUMAN with the residue 147 substituted with Phosphotyrosine" [UniProtKB:P62826] xref: UniProtKB:P62826 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001693 ! RAN_HUMAN [Term] id: CCO:B0013709 name: RAP1A_HUMAN-Cysteine methyl ester181 def: "Protein RAP1A_HUMAN with the residue 181 substituted with Cysteine methyl ester" [UniProtKB:P62834] xref: UniProtKB:P62834 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001694 ! RAP1A_HUMAN [Term] id: CCO:B0013710 name: RARA_HUMAN-Phosphoserine77 def: "Protein RARA_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P10276] comment: by CDK7; By similarity xref: UniProtKB:P10276 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024853 ! RARA_HUMAN [Term] id: CCO:B0013711 name: RARA_HUMAN-Phosphoserine449 def: "Protein RARA_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:P10276] comment: By similarity xref: UniProtKB:P10276 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0024853 ! RARA_HUMAN [Term] id: CCO:B0013712 name: RARA_HUMAN-Phosphoserine456 def: "Protein RARA_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:P10276] comment: By similarity xref: UniProtKB:P10276 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024853 ! RARA_HUMAN [Term] id: CCO:B0013713 name: RARA_HUMAN-Phosphoserine461 def: "Protein RARA_HUMAN with the residue 461 substituted with Phosphoserine" [UniProtKB:P10276] comment: By similarity xref: UniProtKB:P10276 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024853 ! RARA_HUMAN [Term] id: CCO:B0013714 name: RASA1_HUMAN-Phosphotyrosine615 def: "Protein RASA1_HUMAN with the residue 615 substituted with Phosphotyrosine" [UniProtKB:P20936] xref: UniProtKB:P20936 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004200 ! potassium channel inhibitor activity relationship: has_function CCO:F0008038 ! GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005995 ! RASA1_HUMAN [Term] id: CCO:B0013715 name: RASH_HUMAN-Cysteine methyl ester186 def: "Protein RASH_HUMAN with the residue 186 substituted with Cysteine methyl ester" [UniProtKB:P01112] xref: UniProtKB:P01112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001467 ! RASH_HUMAN [Term] id: CCO:B0013716 name: RASK_HUMAN-ester186 def: "Protein RASK_HUMAN with the residue 186 substituted with ester" [UniProtKB:P01116] comment: in isoform 2A; xref: UniProtKB:P01116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001468 ! RASK_HUMAN [Term] id: CCO:B0013717 name: RASN_HUMAN-Cysteine methyl ester186 def: "Protein RASN_HUMAN with the residue 186 substituted with Cysteine methyl ester" [UniProtKB:P01111] comment: By similarity xref: UniProtKB:P01111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001466 ! RASN_HUMAN [Term] id: CCO:B0013718 name: RB27A_HUMAN-Cysteine methyl ester221 def: "Protein RB27A_HUMAN with the residue 221 substituted with Cysteine methyl ester" [UniProtKB:P51159] comment: By similarity xref: UniProtKB:P51159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0006223 ! RB27A_HUMAN [Term] id: CCO:B0013719 name: RBBP4_HUMAN-N-acetylalanine2 def: "Protein RBBP4_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q09028] xref: UniProtKB:Q09028 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001727 ! RBBP4_HUMAN [Term] id: CCO:B0013720 name: RBBP5_HUMAN-Phosphoserine182 def: "Protein RBBP5_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q15291] xref: UniProtKB:Q15291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:B0013721 name: RBBP5_HUMAN-Phosphothreonine193 def: "Protein RBBP5_HUMAN with the residue 193 substituted with Phosphothreonine" [UniProtKB:Q15291] xref: UniProtKB:Q15291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:B0013722 name: RBBP5_HUMAN-Phosphothreonine252 def: "Protein RBBP5_HUMAN with the residue 252 substituted with Phosphothreonine" [UniProtKB:Q15291] comment: by CDC2; xref: UniProtKB:Q15291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001616 ! histone methyltransferase complex relationship: transformation_of CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:B0013723 name: RBBP5_HUMAN-Phosphoserine350 def: "Protein RBBP5_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:Q15291] xref: UniProtKB:Q15291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:B0013724 name: RBBP5_HUMAN-Phosphoserine388 def: "Protein RBBP5_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q15291] xref: UniProtKB:Q15291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:B0013725 name: RBBP5_HUMAN-Phosphoserine389 def: "Protein RBBP5_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:Q15291] xref: UniProtKB:Q15291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:B0013726 name: RBBP5_HUMAN-Phosphoserine497 def: "Protein RBBP5_HUMAN with the residue 497 substituted with Phosphoserine" [UniProtKB:Q15291] comment: by CDC2; xref: UniProtKB:Q15291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:B0013744 name: RBBP7_HUMAN-N6-acetyllysine119 def: "Protein RBBP7_HUMAN with the residue 119 substituted with N6-acetyllysine" [UniProtKB:Q16576] xref: UniProtKB:Q16576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005809 ! RBBP7_HUMAN [Term] id: CCO:B0013745 name: RBBP7_HUMAN-Phosphoserine413 def: "Protein RBBP7_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q16576] xref: UniProtKB:Q16576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005809 ! RBBP7_HUMAN [Term] id: CCO:B0013746 name: RBBP7_HUMAN-Phosphothreonine416 def: "Protein RBBP7_HUMAN with the residue 416 substituted with Phosphothreonine" [UniProtKB:Q16576] xref: UniProtKB:Q16576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005809 ! RBBP7_HUMAN [Term] id: CCO:B0013747 name: RBBP8_HUMAN-Phosphoserine327 def: "Protein RBBP8_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:Q99708] xref: UniProtKB:Q99708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002084 ! RBBP8_HUMAN [Term] id: CCO:B0013748 name: RBBP8_HUMAN-Phosphoserine664 def: "Protein RBBP8_HUMAN with the residue 664 substituted with Phosphoserine" [UniProtKB:Q99708] comment: by ATM; xref: UniProtKB:Q99708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002084 ! RBBP8_HUMAN [Term] id: CCO:B0013749 name: RBBP8_HUMAN-Phosphoserine679 def: "Protein RBBP8_HUMAN with the residue 679 substituted with Phosphoserine" [UniProtKB:Q99708] xref: UniProtKB:Q99708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002084 ! RBBP8_HUMAN [Term] id: CCO:B0013750 name: RBBP8_HUMAN-Phosphoserine745 def: "Protein RBBP8_HUMAN with the residue 745 substituted with Phosphoserine" [UniProtKB:Q99708] comment: by ATM; xref: UniProtKB:Q99708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002084 ! RBBP8_HUMAN [Term] id: CCO:B0013751 name: RBCC1_HUMAN-Phosphoserine237 def: "Protein RBCC1_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q8TDY2] xref: UniProtKB:Q8TDY2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001995 ! RBCC1_HUMAN [Term] id: CCO:B0013752 name: RBCC1_HUMAN-Phosphoserine537 def: "Protein RBCC1_HUMAN with the residue 537 substituted with Phosphoserine" [UniProtKB:Q8TDY2] xref: UniProtKB:Q8TDY2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001995 ! RBCC1_HUMAN [Term] id: CCO:B0013753 name: RBCC1_HUMAN-Phosphothreonine666 def: "Protein RBCC1_HUMAN with the residue 666 substituted with Phosphothreonine" [UniProtKB:Q8TDY2] comment: By similarity xref: UniProtKB:Q8TDY2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001995 ! RBCC1_HUMAN [Term] id: CCO:B0013754 name: RBL1_HUMAN-Phosphothreonine332 def: "Protein RBL1_HUMAN with the residue 332 substituted with Phosphothreonine" [UniProtKB:P28749] comment: by CDK2; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013755 name: RBL1_HUMAN-Phosphothreonine369 def: "Protein RBL1_HUMAN with the residue 369 substituted with Phosphothreonine" [UniProtKB:P28749] comment: by CDK4; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013756 name: RBL1_HUMAN-Phosphothreonine385 def: "Protein RBL1_HUMAN with the residue 385 substituted with Phosphothreonine" [UniProtKB:P28749] comment: by CDK2; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013757 name: RBL1_HUMAN-Phosphoserine640 def: "Protein RBL1_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:P28749] comment: by CDK2 and CDK4; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013758 name: RBL1_HUMAN-Phosphoserine650 def: "Protein RBL1_HUMAN with the residue 650 substituted with Phosphoserine" [UniProtKB:P28749] xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013759 name: RBL1_HUMAN-Phosphoserine762 def: "Protein RBL1_HUMAN with the residue 762 substituted with Phosphoserine" [UniProtKB:P28749] comment: by CDK2; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013760 name: RBL1_HUMAN-Phosphoserine964 def: "Protein RBL1_HUMAN with the residue 964 substituted with Phosphoserine" [UniProtKB:P28749] comment: by CDK2 and CDK4; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013761 name: RBL1_HUMAN-Phosphoserine975 def: "Protein RBL1_HUMAN with the residue 975 substituted with Phosphoserine" [UniProtKB:P28749] comment: by CDK2 and CDK4; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013762 name: RBL1_HUMAN-Phosphoserine988 def: "Protein RBL1_HUMAN with the residue 988 substituted with Phosphoserine" [UniProtKB:P28749] comment: by CDK2; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013763 name: RBL1_HUMAN-Phosphothreonine997 def: "Protein RBL1_HUMAN with the residue 997 substituted with Phosphothreonine" [UniProtKB:P28749] comment: by CDK2; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013764 name: RBL1_HUMAN-Phosphoserine1009 def: "Protein RBL1_HUMAN with the residue 1009 substituted with Phosphoserine" [UniProtKB:P28749] comment: by CDK2; xref: UniProtKB:P28749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001567 ! RBL1_HUMAN [Term] id: CCO:B0013765 name: RBL2_HUMAN-Phosphoserine413 def: "Protein RBL2_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q08999] comment: By similarity xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013766 name: RBL2_HUMAN-Phosphothreonine417 def: "Protein RBL2_HUMAN with the residue 417 substituted with Phosphothreonine" [UniProtKB:Q08999] comment: By similarity xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013767 name: RBL2_HUMAN-Phosphoserine639 def: "Protein RBL2_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:Q08999] xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013768 name: RBL2_HUMAN-Phosphothreonine642 def: "Protein RBL2_HUMAN with the residue 642 substituted with Phosphothreonine" [UniProtKB:Q08999] comment: By similarity xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013769 name: RBL2_HUMAN-Phosphoserine672 def: "Protein RBL2_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:Q08999] xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013770 name: RBL2_HUMAN-Phosphoserine948 def: "Protein RBL2_HUMAN with the residue 948 substituted with Phosphoserine" [UniProtKB:Q08999] comment: By similarity xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013771 name: RBL2_HUMAN-Phosphoserine952 def: "Protein RBL2_HUMAN with the residue 952 substituted with Phosphoserine" [UniProtKB:Q08999] xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013772 name: RBL2_HUMAN-Phosphoserine966 def: "Protein RBL2_HUMAN with the residue 966 substituted with Phosphoserine" [UniProtKB:Q08999] xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013773 name: RBL2_HUMAN-Phosphoserine971 def: "Protein RBL2_HUMAN with the residue 971 substituted with Phosphoserine" [UniProtKB:Q08999] comment: Probable xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013774 name: RBL2_HUMAN-Phosphoserine972 def: "Protein RBL2_HUMAN with the residue 972 substituted with Phosphoserine" [UniProtKB:Q08999] comment: Probable xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013775 name: RBL2_HUMAN-Phosphoserine973 def: "Protein RBL2_HUMAN with the residue 973 substituted with Phosphoserine" [UniProtKB:Q08999] comment: Probable xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013776 name: RBL2_HUMAN-Phosphothreonine974 def: "Protein RBL2_HUMAN with the residue 974 substituted with Phosphothreonine" [UniProtKB:Q08999] comment: Probable xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013777 name: RBL2_HUMAN-Phosphoserine981 def: "Protein RBL2_HUMAN with the residue 981 substituted with Phosphoserine" [UniProtKB:Q08999] comment: Probable xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013778 name: RBL2_HUMAN-Phosphoserine982 def: "Protein RBL2_HUMAN with the residue 982 substituted with Phosphoserine" [UniProtKB:Q08999] comment: Probable xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013779 name: RBL2_HUMAN-Phosphothreonine986 def: "Protein RBL2_HUMAN with the residue 986 substituted with Phosphothreonine" [UniProtKB:Q08999] xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0013789 name: RBM5_HUMAN-Phosphoserine59 def: "Protein RBM5_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:P52756] xref: UniProtKB:P52756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001660 ! RBM5_HUMAN [Term] id: CCO:B0013790 name: RBM5_HUMAN-Phosphoserine69 def: "Protein RBM5_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:P52756] comment: By similarity xref: UniProtKB:P52756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001660 ! RBM5_HUMAN [Term] id: CCO:B0013791 name: RBM5_HUMAN-Phosphoserine621 def: "Protein RBM5_HUMAN with the residue 621 substituted with Phosphoserine" [UniProtKB:P52756] xref: UniProtKB:P52756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001660 ! RBM5_HUMAN [Term] id: CCO:B0013792 name: RBM5_HUMAN-Phosphoserine624 def: "Protein RBM5_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:P52756] xref: UniProtKB:P52756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001660 ! RBM5_HUMAN [Term] id: CCO:B0013793 name: RBM7_HUMAN-Phosphoserine136 def: "Protein RBM7_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q9Y580] xref: UniProtKB:Q9Y580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002255 ! RBM7_HUMAN [Term] id: CCO:B0013794 name: RBM7_HUMAN-Phosphoserine137 def: "Protein RBM7_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q9Y580] xref: UniProtKB:Q9Y580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002255 ! RBM7_HUMAN [Term] id: CCO:B0013795 name: RBM8A_HUMAN-Phosphoserine42 def: "Protein RBM8A_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q9Y5S9] xref: UniProtKB:Q9Y5S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005223 ! RBM8A_HUMAN [Term] id: CCO:B0013796 name: RBM8A_HUMAN-Phosphoserine46 def: "Protein RBM8A_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:Q9Y5S9] xref: UniProtKB:Q9Y5S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005223 ! RBM8A_HUMAN [Term] id: CCO:B0013797 name: RBM8A_HUMAN-Phosphoserine166 def: "Protein RBM8A_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q9Y5S9] xref: UniProtKB:Q9Y5S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005223 ! RBM8A_HUMAN [Term] id: CCO:B0013798 name: RBM8A_HUMAN-Phosphoserine168 def: "Protein RBM8A_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q9Y5S9] xref: UniProtKB:Q9Y5S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005223 ! RBM8A_HUMAN [Term] id: CCO:B0013799 name: RB_HUMAN-Phosphoserine249 def: "Protein RB_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:P06400] comment: by CDC2; xref: UniProtKB:P06400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001491 ! RB_HUMAN [Term] id: CCO:B0013800 name: RB_HUMAN-Phosphothreonine252 def: "Protein RB_HUMAN with the residue 252 substituted with Phosphothreonine" [UniProtKB:P06400] comment: by CDC2; xref: UniProtKB:P06400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001491 ! RB_HUMAN [Term] id: CCO:B0013801 name: RB_HUMAN-Phosphothreonine373 def: "Protein RB_HUMAN with the residue 373 substituted with Phosphothreonine" [UniProtKB:P06400] comment: by CDC2; xref: UniProtKB:P06400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001491 ! RB_HUMAN [Term] id: CCO:B0013802 name: RB_HUMAN-Phosphoserine807 def: "Protein RB_HUMAN with the residue 807 substituted with Phosphoserine" [UniProtKB:P06400] comment: by CDC2; xref: UniProtKB:P06400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001491 ! RB_HUMAN [Term] id: CCO:B0013803 name: RB_HUMAN-Phosphoserine811 def: "Protein RB_HUMAN with the residue 811 substituted with Phosphoserine" [UniProtKB:P06400] comment: by CDC2; xref: UniProtKB:P06400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001491 ! RB_HUMAN [Term] id: CCO:B0013804 name: RB_HUMAN-Phosphothreonine826 def: "Protein RB_HUMAN with the residue 826 substituted with Phosphothreonine" [UniProtKB:P06400] comment: By similarity xref: UniProtKB:P06400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0001491 ! RB_HUMAN [Term] id: CCO:B0013805 name: RCC1_HUMAN-Phosphoserine11 def: "Protein RCC1_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P18754] xref: UniProtKB:P18754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001533 ! RCC1_HUMAN [Term] id: CCO:B0013806 name: RCC1_HUMAN-Phosphoserine403 def: "Protein RCC1_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:P18754] xref: UniProtKB:P18754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001533 ! RCC1_HUMAN [Term] id: CCO:B0013807 name: RCC1_HUMAN-Phosphoserine405 def: "Protein RCC1_HUMAN with the residue 405 substituted with Phosphoserine" [UniProtKB:P18754] xref: UniProtKB:P18754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001533 ! RCC1_HUMAN [Term] id: CCO:B0013808 name: RCC1_HUMAN-Phosphoserine406 def: "Protein RCC1_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:P18754] xref: UniProtKB:P18754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001533 ! RCC1_HUMAN [Term] id: CCO:B0013809 name: RCC1_HUMAN-Phosphothreonine411 def: "Protein RCC1_HUMAN with the residue 411 substituted with Phosphothreonine" [UniProtKB:P18754] xref: UniProtKB:P18754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001392 ! Ran guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000117 ! nuclear chromatin relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001533 ! RCC1_HUMAN [Term] id: CCO:B0013810 name: RCC2_HUMAN-Phosphothreonine20 def: "Protein RCC2_HUMAN with the residue 20 substituted with Phosphothreonine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013811 name: RCC2_HUMAN-Phosphoserine43 def: "Protein RCC2_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013812 name: RCC2_HUMAN-Phosphoserine44 def: "Protein RCC2_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013813 name: RCC2_HUMAN-Phosphoserine45 def: "Protein RCC2_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013814 name: RCC2_HUMAN-Phosphoserine46 def: "Protein RCC2_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013815 name: RCC2_HUMAN-Phosphoserine50 def: "Protein RCC2_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013816 name: RCC2_HUMAN-Phosphoserine51 def: "Protein RCC2_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013817 name: RCC2_HUMAN-Phosphoserine347 def: "Protein RCC2_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q9P258] xref: UniProtKB:Q9P258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002186 ! RCC2_HUMAN [Term] id: CCO:B0013818 name: RED_HUMAN-Phosphothreonine485 def: "Protein RED_HUMAN with the residue 485 substituted with Phosphothreonine" [UniProtKB:Q13123] xref: UniProtKB:Q13123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006239 ! RED_HUMAN [Term] id: CCO:B0013819 name: RENT1_HUMAN-Phosphoserine1089 def: "Protein RENT1_HUMAN with the residue 1089 substituted with Phosphoserine" [UniProtKB:Q92900] comment: Probable xref: UniProtKB:Q92900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002024 ! RENT1_HUMAN [Term] id: CCO:B0013820 name: RENT1_HUMAN-Phosphoserine1107 def: "Protein RENT1_HUMAN with the residue 1107 substituted with Phosphoserine" [UniProtKB:Q92900] xref: UniProtKB:Q92900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002024 ! RENT1_HUMAN [Term] id: CCO:B0013821 name: RENT1_HUMAN-Phosphoserine1127 def: "Protein RENT1_HUMAN with the residue 1127 substituted with Phosphoserine" [UniProtKB:Q92900] xref: UniProtKB:Q92900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002024 ! RENT1_HUMAN [Term] id: CCO:B0013822 name: RFA1_HUMAN-Phosphothreonine180 def: "Protein RFA1_HUMAN with the residue 180 substituted with Phosphothreonine" [UniProtKB:P27694] xref: UniProtKB:P27694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001562 ! RFA1_HUMAN [Term] id: CCO:B0013823 name: RFA2_HUMAN-N-acetylmethionine1 def: "Protein RFA2_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P15927] xref: UniProtKB:P15927 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000267 ! DNA replication factor A complex relationship: transformation_of CCO:B0005500 ! RFA2_HUMAN [Term] id: CCO:B0013824 name: RFA2_HUMAN-Phosphothreonine21 def: "Protein RFA2_HUMAN with the residue 21 substituted with Phosphothreonine" [UniProtKB:P15927] comment: by PRKDC; in vitro; xref: UniProtKB:P15927 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005500 ! RFA2_HUMAN [Term] id: CCO:B0013825 name: RFA2_HUMAN-Phosphoserine29 def: "Protein RFA2_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:P15927] comment: by CDC2; in vitro; xref: UniProtKB:P15927 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005500 ! RFA2_HUMAN [Term] id: CCO:B0013826 name: RFA2_HUMAN-Phosphoserine33 def: "Protein RFA2_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:P15927] comment: by PRKDC; in vitro; xref: UniProtKB:P15927 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005500 ! RFA2_HUMAN [Term] id: CCO:B0013827 name: RFC1_HUMAN-Phosphoserine69 def: "Protein RFC1_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013828 name: RFC1_HUMAN-Phosphoserine71 def: "Protein RFC1_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013829 name: RFC1_HUMAN-Phosphoserine73 def: "Protein RFC1_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013830 name: RFC1_HUMAN-Phosphoserine108 def: "Protein RFC1_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013831 name: RFC1_HUMAN-Phosphothreonine110 def: "Protein RFC1_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000281 ! DNA clamp loader activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000268 ! DNA replication factor C complex relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013832 name: RFC1_HUMAN-Phosphoserine156 def: "Protein RFC1_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013833 name: RFC1_HUMAN-Phosphothreonine161 def: "Protein RFC1_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013834 name: RFC1_HUMAN-Phosphoserine173 def: "Protein RFC1_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013835 name: RFC1_HUMAN-Phosphoserine190 def: "Protein RFC1_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0013836 name: RFX1_HUMAN-Phosphoserine120 def: "Protein RFX1_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P22670] xref: UniProtKB:P22670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006243 ! RFX1_HUMAN [Term] id: CCO:B0013837 name: RGAP1_HUMAN-Phosphothreonine161 def: "Protein RGAP1_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013838 name: RGAP1_HUMAN-Phosphoserine164 def: "Protein RGAP1_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013839 name: RGAP1_HUMAN-Phosphoserine170 def: "Protein RGAP1_HUMAN with the residue 170 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013840 name: RGAP1_HUMAN-Phosphoserine185 def: "Protein RGAP1_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013841 name: RGAP1_HUMAN-Phosphoserine187 def: "Protein RGAP1_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013842 name: RGAP1_HUMAN-Phosphoserine203 def: "Protein RGAP1_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013843 name: RGAP1_HUMAN-Phosphoserine206 def: "Protein RGAP1_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013844 name: RGAP1_HUMAN-Phosphoserine214 def: "Protein RGAP1_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013845 name: RGAP1_HUMAN-Phosphothreonine342 def: "Protein RGAP1_HUMAN with the residue 342 substituted with Phosphothreonine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013846 name: RGAP1_HUMAN-Phosphoserine387 def: "Protein RGAP1_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013847 name: RGAP1_HUMAN-Phosphothreonine580 def: "Protein RGAP1_HUMAN with the residue 580 substituted with Phosphothreonine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013848 name: RGAP1_HUMAN-Phosphothreonine588 def: "Protein RGAP1_HUMAN with the residue 588 substituted with Phosphothreonine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013849 name: RGAP1_HUMAN-Phosphoserine590 def: "Protein RGAP1_HUMAN with the residue 590 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013850 name: RGAP1_HUMAN-Phosphothreonine606 def: "Protein RGAP1_HUMAN with the residue 606 substituted with Phosphothreonine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013851 name: RGAP1_HUMAN-Phosphoserine628 def: "Protein RGAP1_HUMAN with the residue 628 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0013852 name: RGC32_HUMAN-Phosphoserine9 def: "Protein RGC32_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:Q9H4X1] xref: UniProtKB:Q9H4X1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002137 ! RGC32_HUMAN [Term] id: CCO:B0013853 name: RGC32_HUMAN-Phosphoserine29 def: "Protein RGC32_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q9H4X1] xref: UniProtKB:Q9H4X1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002137 ! RGC32_HUMAN [Term] id: CCO:B0013854 name: RGC32_HUMAN-Phosphoserine44 def: "Protein RGC32_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q9H4X1] xref: UniProtKB:Q9H4X1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002137 ! RGC32_HUMAN [Term] id: CCO:B0013855 name: RGC32_HUMAN-Phosphothreonine111 def: "Protein RGC32_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:Q9H4X1] comment: by CDC2; xref: UniProtKB:Q9H4X1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0002137 ! RGC32_HUMAN [Term] id: CCO:B0013856 name: RHOB_HUMAN-ADP-ribosylasparagine41 def: "Protein RHOB_HUMAN with the residue 41 substituted with ADP-ribosylasparagine" [UniProtKB:P62745] comment: by botulinum toxin; By similarity xref: UniProtKB:P62745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001692 ! RHOB_HUMAN [Term] id: CCO:B0013857 name: RHOB_HUMAN-Cysteine methyl ester193 def: "Protein RHOB_HUMAN with the residue 193 substituted with Cysteine methyl ester" [UniProtKB:P62745] xref: UniProtKB:P62745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001692 ! RHOB_HUMAN [Term] id: CCO:B0013858 name: RHOG_HUMAN-ADP-ribosylasparagine39 def: "Protein RHOG_HUMAN with the residue 39 substituted with ADP-ribosylasparagine" [UniProtKB:P84095] comment: by botulinum toxin; By similarity xref: UniProtKB:P84095 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001704 ! RHOG_HUMAN [Term] id: CCO:B0013859 name: RHOG_HUMAN-Cysteine methyl ester188 def: "Protein RHOG_HUMAN with the residue 188 substituted with Cysteine methyl ester" [UniProtKB:P84095] comment: By similarity xref: UniProtKB:P84095 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001704 ! RHOG_HUMAN [Term] id: CCO:B0013860 name: RIF1_HUMAN-Phosphoserine782 def: "Protein RIF1_HUMAN with the residue 782 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013861 name: RIF1_HUMAN-Phosphoserine1454 def: "Protein RIF1_HUMAN with the residue 1454 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013862 name: RIF1_HUMAN-Phosphoserine1513 def: "Protein RIF1_HUMAN with the residue 1513 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013863 name: RIF1_HUMAN-Phosphothreonine1518 def: "Protein RIF1_HUMAN with the residue 1518 substituted with Phosphothreonine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013864 name: RIF1_HUMAN-Phosphoserine1542 def: "Protein RIF1_HUMAN with the residue 1542 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013865 name: RIF1_HUMAN-Phosphoserine1579 def: "Protein RIF1_HUMAN with the residue 1579 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013866 name: RIF1_HUMAN-Phosphoserine1688 def: "Protein RIF1_HUMAN with the residue 1688 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013867 name: RIF1_HUMAN-Phosphoserine1851 def: "Protein RIF1_HUMAN with the residue 1851 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013868 name: RIF1_HUMAN-Phosphoserine2161 def: "Protein RIF1_HUMAN with the residue 2161 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013869 name: RIF1_HUMAN-Phosphoserine2243 def: "Protein RIF1_HUMAN with the residue 2243 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0013870 name: RIN1_HUMAN-Phosphotyrosine36 def: "Protein RIN1_HUMAN with the residue 36 substituted with Phosphotyrosine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0013871 name: RIN1_HUMAN-Phosphoserine333 def: "Protein RIN1_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0013872 name: RIN1_HUMAN-Phosphoserine337 def: "Protein RIN1_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0013873 name: RIN1_HUMAN-Phosphoserine351 def: "Protein RIN1_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q13671] comment: by PKD; xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0013874 name: RIN1_HUMAN-Phosphoserine601 def: "Protein RIN1_HUMAN with the residue 601 substituted with Phosphoserine" [UniProtKB:Q13671] comment: By similarity xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0013875 name: RIPK1_HUMAN-Phosphotyrosine384 def: "Protein RIPK1_HUMAN with the residue 384 substituted with Phosphotyrosine" [UniProtKB:Q13546] xref: UniProtKB:Q13546 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:B0013876 name: RIPK1_HUMAN-Phosphotyrosine387 def: "Protein RIPK1_HUMAN with the residue 387 substituted with Phosphotyrosine" [UniProtKB:Q13546] xref: UniProtKB:Q13546 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:B0013877 name: RIPK1_HUMAN-Phosphoserine389 def: "Protein RIPK1_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:Q13546] xref: UniProtKB:Q13546 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:B0013878 name: RIPK2_HUMAN-Phosphoserine176 def: "Protein RIPK2_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:O43353] xref: UniProtKB:O43353 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005216 ! RIPK2_HUMAN [Term] id: CCO:B0013879 name: RIPK2_HUMAN-Phosphoserine531 def: "Protein RIPK2_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:O43353] xref: UniProtKB:O43353 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005216 ! RIPK2_HUMAN [Term] id: CCO:B0013880 name: RL11_HUMAN-N-acetylalanine2 def: "Protein RL11_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62913] xref: UniProtKB:P62913 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005858 ! RL11_HUMAN [Term] id: CCO:B0013881 name: RL12_HUMAN-Phosphotyrosine14 def: "Protein RL12_HUMAN with the residue 14 substituted with Phosphotyrosine" [UniProtKB:P30050] xref: UniProtKB:P30050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005855 ! RL12_HUMAN [Term] id: CCO:B0013882 name: RL12_HUMAN-Phosphoserine38 def: "Protein RL12_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:P30050] xref: UniProtKB:P30050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0005855 ! RL12_HUMAN [Term] id: CCO:B0013883 name: RL12_HUMAN-Phosphoserine165 def: "Protein RL12_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:P30050] xref: UniProtKB:P30050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005855 ! RL12_HUMAN [Term] id: CCO:B0013884 name: RL18A_HUMAN-Phosphotyrosine63 def: "Protein RL18A_HUMAN with the residue 63 substituted with Phosphotyrosine" [UniProtKB:Q02543] xref: UniProtKB:Q02543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0006300 ! RL18A_HUMAN [Term] id: CCO:B0013885 name: RL18A_HUMAN-Phosphoserine71 def: "Protein RL18A_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q02543] xref: UniProtKB:Q02543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006300 ! RL18A_HUMAN [Term] id: CCO:B0013886 name: RL18_HUMAN-Phosphoserine130 def: "Protein RL18_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q07020] xref: UniProtKB:Q07020 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0005741 ! RL18_HUMAN [Term] id: CCO:B0013887 name: RL24_HUMAN-Phosphothreonine83 def: "Protein RL24_HUMAN with the residue 83 substituted with Phosphothreonine" [UniProtKB:P83731] xref: UniProtKB:P83731 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005856 ! RL24_HUMAN [Term] id: CCO:B0013888 name: RL24_HUMAN-Phosphoserine86 def: "Protein RL24_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:P83731] xref: UniProtKB:P83731 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0005856 ! RL24_HUMAN [Term] id: CCO:B0013889 name: RL28_HUMAN-N-acetylserine2 def: "Protein RL28_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P46779] xref: UniProtKB:P46779 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0005853 ! RL28_HUMAN [Term] id: CCO:B0013890 name: RL4_HUMAN-N-acetylalanine2 def: "Protein RL4_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P36578] xref: UniProtKB:P36578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005861 ! RL4_HUMAN [Term] id: CCO:B0013891 name: RL4_HUMAN-Phosphoserine295 def: "Protein RL4_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:P36578] xref: UniProtKB:P36578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005861 ! RL4_HUMAN [Term] id: CCO:B0013892 name: RL7_HUMAN-N-acetylmethionine1 def: "Protein RL7_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P18124] xref: UniProtKB:P18124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005746 ! RL7_HUMAN [Term] id: CCO:B0013893 name: RL7_HUMAN-Phosphotyrosine139 def: "Protein RL7_HUMAN with the residue 139 substituted with Phosphotyrosine" [UniProtKB:P18124] xref: UniProtKB:P18124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005746 ! RL7_HUMAN [Term] id: CCO:B0013894 name: RL7_HUMAN-Phosphotyrosine195 def: "Protein RL7_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:P18124] xref: UniProtKB:P18124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005746 ! RL7_HUMAN [Term] id: CCO:B0013895 name: RL8_HUMAN-Phosphotyrosine133 def: "Protein RL8_HUMAN with the residue 133 substituted with Phosphotyrosine" [UniProtKB:P62917] xref: UniProtKB:P62917 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005860 ! RL8_HUMAN [Term] id: CCO:B0013896 name: RLA0_HUMAN-Phosphotyrosine24 def: "Protein RLA0_HUMAN with the residue 24 substituted with Phosphotyrosine" [UniProtKB:P05388] xref: UniProtKB:P05388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0005762 ! RLA0_HUMAN [Term] id: CCO:B0013897 name: RLA0_HUMAN-Phosphoserine304 def: "Protein RLA0_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:P05388] xref: UniProtKB:P05388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005762 ! RLA0_HUMAN [Term] id: CCO:B0013898 name: RLA0_HUMAN-Phosphoserine307 def: "Protein RLA0_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:P05388] xref: UniProtKB:P05388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005762 ! RLA0_HUMAN [Term] id: CCO:B0013899 name: RLA1_HUMAN-Phosphoserine5 def: "Protein RLA1_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:P05386] xref: UniProtKB:P05386 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:B0013900 name: RLA1_HUMAN-Phosphotyrosine11 def: "Protein RLA1_HUMAN with the residue 11 substituted with Phosphotyrosine" [UniProtKB:P05386] xref: UniProtKB:P05386 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:B0013901 name: RLA1_HUMAN-Phosphoserine12 def: "Protein RLA1_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:P05386] xref: UniProtKB:P05386 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:B0013902 name: RLA1_HUMAN-Phosphoserine101 def: "Protein RLA1_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:P05386] xref: UniProtKB:P05386 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:B0013903 name: RLA1_HUMAN-Phosphoserine104 def: "Protein RLA1_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:P05386] xref: UniProtKB:P05386 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:B0013904 name: RLA2_HUMAN-Phosphoserine17 def: "Protein RLA2_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:P05387] xref: UniProtKB:P05387 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:B0013905 name: RLA2_HUMAN-Phosphoserine102 def: "Protein RLA2_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:P05387] xref: UniProtKB:P05387 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:B0013906 name: RLA2_HUMAN-Phosphoserine105 def: "Protein RLA2_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:P05387] xref: UniProtKB:P05387 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:B0013907 name: RMI1_HUMAN-Phosphoserine292 def: "Protein RMI1_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q9H9A7] xref: UniProtKB:Q9H9A7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:B0013908 name: RNC_HUMAN-Phosphoserine284 def: "Protein RNC_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q9NRR4] xref: UniProtKB:Q9NRR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000921 ! ribonuclease III activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006026 ! RNC_HUMAN [Term] id: CCO:B0013909 name: ROA1_HUMAN-N-acetylserine2 def: "Protein ROA1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013910 name: ROA1_HUMAN-Phosphoserine4 def: "Protein ROA1_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013911 name: ROA1_HUMAN-Phosphoserine6 def: "Protein ROA1_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013912 name: ROA1_HUMAN-Phosphoserine91 def: "Protein ROA1_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013913 name: ROA1_HUMAN-Phosphoserine95 def: "Protein ROA1_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013914 name: ROA1_HUMAN-Phosphothreonine138 def: "Protein ROA1_HUMAN with the residue 138 substituted with Phosphothreonine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013915 name: ROA1_HUMAN-Phosphotyrosine167 def: "Protein ROA1_HUMAN with the residue 167 substituted with Phosphotyrosine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013916 name: ROA1_HUMAN-Omega-N-methylated arginine194 def: "Protein ROA1_HUMAN with the residue 194 substituted with Omega-N-methylated arginine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013917 name: ROA1_HUMAN-Omega-N-methylated arginine206 def: "Protein ROA1_HUMAN with the residue 206 substituted with Omega-N-methylated arginine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013918 name: ROA1_HUMAN-Omega-N-methylated arginine225 def: "Protein ROA1_HUMAN with the residue 225 substituted with Omega-N-methylated arginine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013919 name: ROA1_HUMAN-Phosphoserine311 def: "Protein ROA1_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:P09651] comment: By similarity xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013920 name: ROA1_HUMAN-Phosphoserine338 def: "Protein ROA1_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013921 name: ROA1_HUMAN-Phosphotyrosine347 def: "Protein ROA1_HUMAN with the residue 347 substituted with Phosphotyrosine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013922 name: ROA1_HUMAN-N6-acetyllysine350 def: "Protein ROA1_HUMAN with the residue 350 substituted with N6-acetyllysine" [UniProtKB:P09651] xref: UniProtKB:P09651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005774 ! ROA1_HUMAN [Term] id: CCO:B0013923 name: ROA2_HUMAN-Phosphothreonine176 def: "Protein ROA2_HUMAN with the residue 176 substituted with Phosphothreonine" [UniProtKB:P22626] xref: UniProtKB:P22626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005725 ! ROA2_HUMAN [Term] id: CCO:B0013924 name: ROA2_HUMAN-Omega-N-methylarginine203 def: "Protein ROA2_HUMAN with the residue 203 substituted with Omega-N-methylarginine" [UniProtKB:P22626] xref: UniProtKB:P22626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005725 ! ROA2_HUMAN [Term] id: CCO:B0013925 name: ROA2_HUMAN-Phosphoserine212 def: "Protein ROA2_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:P22626] xref: UniProtKB:P22626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005725 ! ROA2_HUMAN [Term] id: CCO:B0013926 name: ROA2_HUMAN-Phosphoserine259 def: "Protein ROA2_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:P22626] xref: UniProtKB:P22626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005790 ! single-stranded telomeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0005725 ! ROA2_HUMAN [Term] id: CCO:B0013927 name: ROA2_HUMAN-Phosphoserine341 def: "Protein ROA2_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:P22626] xref: UniProtKB:P22626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005725 ! ROA2_HUMAN [Term] id: CCO:B0013928 name: ROA2_HUMAN-Phosphoserine344 def: "Protein ROA2_HUMAN with the residue 344 substituted with Phosphoserine" [UniProtKB:P22626] xref: UniProtKB:P22626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005725 ! ROA2_HUMAN [Term] id: CCO:B0013929 name: ROA2_HUMAN-Phosphotyrosine347 def: "Protein ROA2_HUMAN with the residue 347 substituted with Phosphotyrosine" [UniProtKB:P22626] xref: UniProtKB:P22626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005725 ! ROA2_HUMAN [Term] id: CCO:B0013930 name: RPAC1_HUMAN-Phosphotyrosine33 def: "Protein RPAC1_HUMAN with the residue 33 substituted with Phosphotyrosine" [UniProtKB:O15160] xref: UniProtKB:O15160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000323 ! DNA-directed RNA polymerase I complex relationship: transformation_of CCO:B0005246 ! RPAC1_HUMAN [Term] id: CCO:B0013932 name: RS10_HUMAN-Phosphotyrosine12 def: "Protein RS10_HUMAN with the residue 12 substituted with Phosphotyrosine" [UniProtKB:P46783] xref: UniProtKB:P46783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0005749 ! RS10_HUMAN [Term] id: CCO:B0013933 name: RS10_HUMAN-Phosphoserine146 def: "Protein RS10_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:P46783] xref: UniProtKB:P46783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005749 ! RS10_HUMAN [Term] id: CCO:B0013934 name: RS12_HUMAN-N-acetylalanine2 def: "Protein RS12_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P25398] xref: UniProtKB:P25398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005767 ! RS12_HUMAN [Term] id: CCO:B0013935 name: RS13_HUMAN-Phosphotyrosine38 def: "Protein RS13_HUMAN with the residue 38 substituted with Phosphotyrosine" [UniProtKB:P62277] xref: UniProtKB:P62277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005748 ! RS13_HUMAN [Term] id: CCO:B0013936 name: RS13_HUMAN-Phosphotyrosine128 def: "Protein RS13_HUMAN with the residue 128 substituted with Phosphotyrosine" [UniProtKB:P62277] xref: UniProtKB:P62277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0005748 ! RS13_HUMAN [Term] id: CCO:B0013937 name: RS13_HUMAN-Phosphotyrosine129 def: "Protein RS13_HUMAN with the residue 129 substituted with Phosphotyrosine" [UniProtKB:P62277] xref: UniProtKB:P62277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005748 ! RS13_HUMAN [Term] id: CCO:B0013938 name: RS18_HUMAN-N-acetylserine2 def: "Protein RS18_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62269] xref: UniProtKB:P62269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0005763 ! RS18_HUMAN [Term] id: CCO:B0013939 name: RS20_HUMAN-Phosphothreonine9 def: "Protein RS20_HUMAN with the residue 9 substituted with Phosphothreonine" [UniProtKB:P60866] xref: UniProtKB:P60866 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0005563 ! RS20_HUMAN [Term] id: CCO:B0013940 name: RS24_HUMAN-N-acetylmethionine1 def: "Protein RS24_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P62847] xref: UniProtKB:P62847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0005726 ! RS24_HUMAN [Term] id: CCO:B0013941 name: RS3A_HUMAN-Phosphotyrosine256 def: "Protein RS3A_HUMAN with the residue 256 substituted with Phosphotyrosine" [UniProtKB:P61247] xref: UniProtKB:P61247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005768 ! RS3A_HUMAN [Term] id: CCO:B0013942 name: RS3A_HUMAN-Phosphoserine263 def: "Protein RS3A_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:P61247] xref: UniProtKB:P61247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005768 ! RS3A_HUMAN [Term] id: CCO:B0013943 name: RS7_HUMAN-N-acetylmethionine1 def: "Protein RS7_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P62081] comment: By similarity xref: UniProtKB:P62081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0005758 ! RS7_HUMAN [Term] id: CCO:B0013944 name: RS8_HUMAN-Phosphoserine160 def: "Protein RS8_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:P62241] comment: By similarity xref: UniProtKB:P62241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005734 ! RS8_HUMAN [Term] id: CCO:B0013945 name: RSSA_HUMAN-N-acetylserine2 def: "Protein RSSA_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P08865] xref: UniProtKB:P08865 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005776 ! RSSA_HUMAN [Term] id: CCO:B0013946 name: RSSA_HUMAN-Phosphotyrosine139 def: "Protein RSSA_HUMAN with the residue 139 substituted with Phosphotyrosine" [UniProtKB:P08865] xref: UniProtKB:P08865 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005776 ! RSSA_HUMAN [Term] id: CCO:B0013947 name: RUVB2_HUMAN-Phosphoserine220 def: "Protein RUVB2_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q9Y230] xref: UniProtKB:Q9Y230 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005364 ! RUVB2_HUMAN [Term] id: CCO:B0013948 name: S100B_HUMAN-Blocked amino end (Ser)2 def: "Protein S100B_HUMAN with the residue 2 substituted with Blocked amino end (Ser)" [UniProtKB:P04271] xref: UniProtKB:P04271 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007315 ! S100 beta binding relationship: has_function CCO:F0007317 ! tau protein binding relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:B0013949 name: S10A9_HUMAN-Phosphothreonine113 def: "Protein S10A9_HUMAN with the residue 113 substituted with Phosphothreonine" [UniProtKB:P06702] xref: UniProtKB:P06702 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005461 ! S10A9_HUMAN [Term] id: CCO:B0013950 name: S10AB_HUMAN-Phosphoserine6 def: "Protein S10AB_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:P31949] xref: UniProtKB:P31949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:B0013954 name: SAC31_HUMAN-Phosphoserine401 def: "Protein SAC31_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:A6NKF1] xref: UniProtKB:A6NKF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: transformation_of CCO:B0001334 ! SAC31_HUMAN [Term] id: CCO:B0013955 name: SACS_HUMAN-Phosphothreonine4263 def: "Protein SACS_HUMAN with the residue 4263 substituted with Phosphothreonine" [UniProtKB:Q9NZJ4] comment: By similarity xref: UniProtKB:Q9NZJ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0005994 ! SACS_HUMAN [Term] id: CCO:B0013956 name: SAE1_HUMAN-Phosphoserine185 def: "Protein SAE1_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:Q9UBE0] xref: UniProtKB:Q9UBE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001197 ! ubiquitin activating enzyme activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0002013 ! small protein activating enzyme activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005780 ! ATP-dependent protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006046 ! SAE1_HUMAN [Term] id: CCO:B0013957 name: SAS10_HUMAN-Phosphoserine37 def: "Protein SAS10_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q9NQZ2] xref: UniProtKB:Q9NQZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006160 ! SAS10_HUMAN [Term] id: CCO:B0013958 name: SAS10_HUMAN-Phosphoserine150 def: "Protein SAS10_HUMAN with the residue 150 substituted with Phosphoserine" [UniProtKB:Q9NQZ2] xref: UniProtKB:Q9NQZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006160 ! SAS10_HUMAN [Term] id: CCO:B0013959 name: SAS10_HUMAN-Phosphoserine365 def: "Protein SAS10_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q9NQZ2] xref: UniProtKB:Q9NQZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006160 ! SAS10_HUMAN [Term] id: CCO:B0013960 name: SAS10_HUMAN-Phosphoserine368 def: "Protein SAS10_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q9NQZ2] xref: UniProtKB:Q9NQZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0002175 ! small-subunit processome relationship: transformation_of CCO:B0006160 ! SAS10_HUMAN [Term] id: CCO:B0013961 name: SASH1_HUMAN-Phosphoserine90 def: "Protein SASH1_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:O94885] xref: UniProtKB:O94885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001444 ! SASH1_HUMAN [Term] id: CCO:B0013962 name: SASH1_HUMAN-Phosphoserine731 def: "Protein SASH1_HUMAN with the residue 731 substituted with Phosphoserine" [UniProtKB:O94885] comment: By similarity xref: UniProtKB:O94885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001444 ! SASH1_HUMAN [Term] id: CCO:B0013963 name: SASH1_HUMAN-Phosphoserine821 def: "Protein SASH1_HUMAN with the residue 821 substituted with Phosphoserine" [UniProtKB:O94885] comment: By similarity xref: UniProtKB:O94885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001444 ! SASH1_HUMAN [Term] id: CCO:B0013964 name: SASH1_HUMAN-Phosphoserine839 def: "Protein SASH1_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:O94885] comment: By similarity xref: UniProtKB:O94885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001444 ! SASH1_HUMAN [Term] id: CCO:B0013965 name: SBP1_HUMAN-Phosphoserine467 def: "Protein SBP1_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:Q13228] comment: By similarity xref: UniProtKB:Q13228 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006083 ! SBP1_HUMAN [Term] id: CCO:B0013966 name: SCFD1_HUMAN-Phosphoserine57 def: "Protein SCFD1_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:Q8WVM8] xref: UniProtKB:Q8WVM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006349 ! SCFD1_HUMAN [Term] id: CCO:B0013967 name: SCFD1_HUMAN-Phosphoserine528 def: "Protein SCFD1_HUMAN with the residue 528 substituted with Phosphoserine" [UniProtKB:Q8WVM8] xref: UniProtKB:Q8WVM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006349 ! SCFD1_HUMAN [Term] id: CCO:B0013968 name: SCG1_HUMAN-Phosphoserine149 def: "Protein SCG1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013969 name: SCG1_HUMAN-N6-acetyllysine153 def: "Protein SCG1_HUMAN with the residue 153 substituted with N6-acetyllysine" [UniProtKB:P05060] comment: By similarity xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013971 name: SCG1_HUMAN-Phosphoserine182 def: "Protein SCG1_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013972 name: SCG1_HUMAN-Phosphoserine183 def: "Protein SCG1_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013973 name: SCG1_HUMAN-Phosphoserine259 def: "Protein SCG1_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013974 name: SCG1_HUMAN-Phosphoserine263 def: "Protein SCG1_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013975 name: SCG1_HUMAN-Phosphoserine311 def: "Protein SCG1_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013976 name: SCG1_HUMAN-Phosphoserine335 def: "Protein SCG1_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013977 name: SCG1_HUMAN-Sulfotyrosine341 def: "Protein SCG1_HUMAN with the residue 341 substituted with Sulfotyrosine" [UniProtKB:P05060] comment: By similarity xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013978 name: SCG1_HUMAN-Phosphoserine377 def: "Protein SCG1_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013979 name: SCG1_HUMAN-Phosphoserine405 def: "Protein SCG1_HUMAN with the residue 405 substituted with Phosphoserine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013980 name: SCG1_HUMAN-Phosphoserine617 def: "Protein SCG1_HUMAN with the residue 617 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013981 name: SCG1_HUMAN-Phosphoserine626 def: "Protein SCG1_HUMAN with the residue 626 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0013982 name: SDS3_HUMAN-Phosphoserine45 def: "Protein SDS3_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0013983 name: SDS3_HUMAN-Phosphothreonine49 def: "Protein SDS3_HUMAN with the residue 49 substituted with Phosphothreonine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0013984 name: SDS3_HUMAN-Phosphothreonine55 def: "Protein SDS3_HUMAN with the residue 55 substituted with Phosphothreonine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000804 ! Sin3 complex relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0013985 name: SDS3_HUMAN-Phosphoserine234 def: "Protein SDS3_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0013986 name: SDS3_HUMAN-Phosphoserine236 def: "Protein SDS3_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0013987 name: SDS3_HUMAN-Phosphothreonine244 def: "Protein SDS3_HUMAN with the residue 244 substituted with Phosphothreonine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0013988 name: SENP7_HUMAN-Phosphoserine377 def: "Protein SENP7_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q9BQF6] xref: UniProtKB:Q9BQF6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006018 ! SENP7_HUMAN [Term] id: CCO:B0013989 name: SENP7_HUMAN-Phosphoserine378 def: "Protein SENP7_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:Q9BQF6] xref: UniProtKB:Q9BQF6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006018 ! SENP7_HUMAN [Term] id: CCO:B0013990 name: SEP11_HUMAN-N-acetylalanine2 def: "Protein SEP11_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9NVA2] xref: UniProtKB:Q9NVA2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0001135 ! septin complex relationship: transformation_of CCO:B0002169 ! SEP11_HUMAN [Term] id: CCO:B0013991 name: SEPT2_HUMAN-Phosphotyrosine17 def: "Protein SEPT2_HUMAN with the residue 17 substituted with Phosphotyrosine" [UniProtKB:Q15019] xref: UniProtKB:Q15019 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001135 ! septin complex relationship: transformation_of CCO:B0001800 ! SEPT2_HUMAN [Term] id: CCO:B0013992 name: SEPT2_HUMAN-Phosphoserine218 def: "Protein SEPT2_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q15019] xref: UniProtKB:Q15019 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001800 ! SEPT2_HUMAN [Term] id: CCO:B0013993 name: SEPT2_HUMAN-Phosphothreonine228 def: "Protein SEPT2_HUMAN with the residue 228 substituted with Phosphothreonine" [UniProtKB:Q15019] comment: By similarity xref: UniProtKB:Q15019 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001800 ! SEPT2_HUMAN [Term] id: CCO:B0013994 name: SEPT3_HUMAN-Phosphoserine91 def: "Protein SEPT3_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q9UH03] comment: By similarity xref: UniProtKB:Q9UH03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002198 ! SEPT3_HUMAN [Term] id: CCO:B0013995 name: SEPT4_HUMAN-Phosphoserine325 def: "Protein SEPT4_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:O43236] xref: UniProtKB:O43236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001382 ! SEPT4_HUMAN [Term] id: CCO:B0013996 name: SEPT5_HUMAN-Phosphoserine327 def: "Protein SEPT5_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:Q99719] comment: By similarity xref: UniProtKB:Q99719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002085 ! SEPT5_HUMAN [Term] id: CCO:B0013997 name: SEPT5_HUMAN-Phosphothreonine336 def: "Protein SEPT5_HUMAN with the residue 336 substituted with Phosphothreonine" [UniProtKB:Q99719] comment: By similarity xref: UniProtKB:Q99719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002085 ! SEPT5_HUMAN [Term] id: CCO:B0013998 name: SEPT6_HUMAN-N-acetylalanine2 def: "Protein SEPT6_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q14141] xref: UniProtKB:Q14141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001775 ! SEPT6_HUMAN [Term] id: CCO:B0013999 name: SEPT6_HUMAN-Phosphoserine408 def: "Protein SEPT6_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:Q14141] xref: UniProtKB:Q14141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001775 ! SEPT6_HUMAN [Term] id: CCO:B0014000 name: SEPT6_HUMAN-Phosphoserine411 def: "Protein SEPT6_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q14141] xref: UniProtKB:Q14141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0001135 ! septin complex relationship: transformation_of CCO:B0001775 ! SEPT6_HUMAN [Term] id: CCO:B0014001 name: SEPT6_HUMAN-Phosphoserine416 def: "Protein SEPT6_HUMAN with the residue 416 substituted with Phosphoserine" [UniProtKB:Q14141] xref: UniProtKB:Q14141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001775 ! SEPT6_HUMAN [Term] id: CCO:B0014002 name: SEPT6_HUMAN-Phosphothreonine418 def: "Protein SEPT6_HUMAN with the residue 418 substituted with Phosphothreonine" [UniProtKB:Q14141] xref: UniProtKB:Q14141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001775 ! SEPT6_HUMAN [Term] id: CCO:B0014003 name: SEPT7_HUMAN-Phosphothreonine228 def: "Protein SEPT7_HUMAN with the residue 228 substituted with Phosphothreonine" [UniProtKB:Q16181] comment: By similarity xref: UniProtKB:Q16181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001816 ! SEPT7_HUMAN [Term] id: CCO:B0014004 name: SEPT7_HUMAN-Phosphotyrosine319 def: "Protein SEPT7_HUMAN with the residue 319 substituted with Phosphotyrosine" [UniProtKB:Q16181] xref: UniProtKB:Q16181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001816 ! SEPT7_HUMAN [Term] id: CCO:B0014005 name: SEPT7_HUMAN-Phosphoserine334 def: "Protein SEPT7_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q16181] xref: UniProtKB:Q16181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001816 ! SEPT7_HUMAN [Term] id: CCO:B0014006 name: SEPT7_HUMAN-Phosphoserine423 def: "Protein SEPT7_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:Q16181] xref: UniProtKB:Q16181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001135 ! septin complex relationship: transformation_of CCO:B0001816 ! SEPT7_HUMAN [Term] id: CCO:B0014007 name: SEPT7_HUMAN-Phosphothreonine426 def: "Protein SEPT7_HUMAN with the residue 426 substituted with Phosphothreonine" [UniProtKB:Q16181] xref: UniProtKB:Q16181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001816 ! SEPT7_HUMAN [Term] id: CCO:B0014008 name: SEPT8_HUMAN-N-acetylalanine2 def: "Protein SEPT8_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q92599] comment: By similarity xref: UniProtKB:Q92599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002015 ! SEPT8_HUMAN [Term] id: CCO:B0014009 name: SEPT8_HUMAN-Phosphoserine10 def: "Protein SEPT8_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:Q92599] comment: By similarity xref: UniProtKB:Q92599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: transformation_of CCO:B0002015 ! SEPT8_HUMAN [Term] id: CCO:B0014010 name: SEPT9_HUMAN-Phosphoserine30 def: "Protein SEPT9_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0014011 name: SEPT9_HUMAN-Phosphothreonine42 def: "Protein SEPT9_HUMAN with the residue 42 substituted with Phosphothreonine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0014012 name: SEPT9_HUMAN-Phosphothreonine49 def: "Protein SEPT9_HUMAN with the residue 49 substituted with Phosphothreonine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0014013 name: SEPT9_HUMAN-Phosphoserine82 def: "Protein SEPT9_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0014014 name: SEPT9_HUMAN-Phosphoserine85 def: "Protein SEPT9_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0014015 name: SEPT9_HUMAN-Phosphoserine89 def: "Protein SEPT9_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0014016 name: SEPT9_HUMAN-Phosphothreonine142 def: "Protein SEPT9_HUMAN with the residue 142 substituted with Phosphothreonine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0014017 name: SESN1_HUMAN-Phosphoserine293 def: "Protein SESN1_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:Q9Y6P5] xref: UniProtKB:Q9Y6P5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002266 ! SESN1_HUMAN [Term] id: CCO:B0014018 name: SET1A_HUMAN-Phosphoserine468 def: "Protein SET1A_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:O15047] xref: UniProtKB:O15047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005613 ! SET1A_HUMAN [Term] id: CCO:B0014019 name: SET1A_HUMAN-Phosphoserine470 def: "Protein SET1A_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:O15047] xref: UniProtKB:O15047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005613 ! SET1A_HUMAN [Term] id: CCO:B0014020 name: SETB1_HUMAN-Phosphothreonine838 def: "Protein SETB1_HUMAN with the residue 838 substituted with Phosphothreonine" [UniProtKB:Q15047] xref: UniProtKB:Q15047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:B0014021 name: SETB1_HUMAN-Phosphoserine1179 def: "Protein SETB1_HUMAN with the residue 1179 substituted with Phosphoserine" [UniProtKB:Q15047] xref: UniProtKB:Q15047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:B0014022 name: SETB1_HUMAN-Phosphothreonine1180 def: "Protein SETB1_HUMAN with the residue 1180 substituted with Phosphothreonine" [UniProtKB:Q15047] xref: UniProtKB:Q15047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:B0014023 name: SETB1_HUMAN-Phosphoserine1190 def: "Protein SETB1_HUMAN with the residue 1190 substituted with Phosphoserine" [UniProtKB:Q15047] xref: UniProtKB:Q15047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:B0014024 name: SET_HUMAN-Phosphoserine7 def: "Protein SET_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q01105] xref: UniProtKB:Q01105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005519 ! SET_HUMAN [Term] id: CCO:B0014025 name: SET_HUMAN-Phosphoserine30 def: "Protein SET_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q01105] comment: By similarity xref: UniProtKB:Q01105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005519 ! SET_HUMAN [Term] id: CCO:B0014026 name: SFPQ_HUMAN-Omega-N-methylated arginine7 def: "Protein SFPQ_HUMAN with the residue 7 substituted with Omega-N-methylated arginine" [UniProtKB:P23246] xref: UniProtKB:P23246 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:B0014027 name: SFPQ_HUMAN-Omega-N-methylated arginine9 def: "Protein SFPQ_HUMAN with the residue 9 substituted with Omega-N-methylated arginine" [UniProtKB:P23246] xref: UniProtKB:P23246 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:B0014028 name: SFPQ_HUMAN-Omega-N-methylated arginine19 def: "Protein SFPQ_HUMAN with the residue 19 substituted with Omega-N-methylated arginine" [UniProtKB:P23246] xref: UniProtKB:P23246 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:B0014029 name: SFPQ_HUMAN-Omega-N-methylated arginine25 def: "Protein SFPQ_HUMAN with the residue 25 substituted with Omega-N-methylated arginine" [UniProtKB:P23246] xref: UniProtKB:P23246 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:B0014030 name: SFPQ_HUMAN-Phosphoserine33 def: "Protein SFPQ_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:P23246] xref: UniProtKB:P23246 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:B0014031 name: SFRS1_HUMAN-N-acetylserine2 def: "Protein SFRS1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q07955] comment: Potential xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014032 name: SFRS1_HUMAN-Phosphoserine2 def: "Protein SFRS1_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014033 name: SFRS1_HUMAN-Omega-N-methylarginine93 def: "Protein SFRS1_HUMAN with the residue 93 substituted with Omega-N-methylarginine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014034 name: SFRS1_HUMAN-Omega-N-methylated arginine97 def: "Protein SFRS1_HUMAN with the residue 97 substituted with Omega-N-methylated arginine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014035 name: SFRS1_HUMAN-Omega-N-methylarginine109 def: "Protein SFRS1_HUMAN with the residue 109 substituted with Omega-N-methylarginine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014036 name: SFRS1_HUMAN-Phosphotyrosine189 def: "Protein SFRS1_HUMAN with the residue 189 substituted with Phosphotyrosine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014037 name: SFRS1_HUMAN-Phosphoserine199 def: "Protein SFRS1_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014038 name: SFRS1_HUMAN-Phosphoserine201 def: "Protein SFRS1_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014039 name: SFRS1_HUMAN-Phosphoserine205 def: "Protein SFRS1_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014040 name: SFRS1_HUMAN-Phosphoserine231 def: "Protein SFRS1_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014041 name: SFRS1_HUMAN-Phosphoserine238 def: "Protein SFRS1_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0014042 name: SGOL2_HUMAN-Phosphoserine266 def: "Protein SGOL2_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q562F6] xref: UniProtKB:Q562F6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001840 ! SGOL2_HUMAN [Term] id: CCO:B0014043 name: SGOL2_HUMAN-Phosphoserine507 def: "Protein SGOL2_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:Q562F6] xref: UniProtKB:Q562F6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001840 ! SGOL2_HUMAN [Term] id: CCO:B0014044 name: SGOL2_HUMAN-Phosphothreonine845 def: "Protein SGOL2_HUMAN with the residue 845 substituted with Phosphothreonine" [UniProtKB:Q562F6] xref: UniProtKB:Q562F6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001070 ! mitotic cohesin complex relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001840 ! SGOL2_HUMAN [Term] id: CCO:B0014045 name: SGTA_HUMAN-Phosphothreonine81 def: "Protein SGTA_HUMAN with the residue 81 substituted with Phosphothreonine" [UniProtKB:O43765] comment: By similarity xref: UniProtKB:O43765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006084 ! SGTA_HUMAN [Term] id: CCO:B0014046 name: SGTA_HUMAN-Phosphoserine301 def: "Protein SGTA_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:O43765] xref: UniProtKB:O43765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006084 ! SGTA_HUMAN [Term] id: CCO:B0014047 name: SGTA_HUMAN-Phosphothreonine303 def: "Protein SGTA_HUMAN with the residue 303 substituted with Phosphothreonine" [UniProtKB:O43765] xref: UniProtKB:O43765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006084 ! SGTA_HUMAN [Term] id: CCO:B0014048 name: SGTA_HUMAN-Phosphoserine305 def: "Protein SGTA_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:O43765] xref: UniProtKB:O43765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006084 ! SGTA_HUMAN [Term] id: CCO:B0014049 name: SH22A_HUMAN-Phosphotyrosine39 def: "Protein SH22A_HUMAN with the residue 39 substituted with Phosphotyrosine" [UniProtKB:Q9NP31] xref: UniProtKB:Q9NP31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005476 ! SH22A_HUMAN [Term] id: CCO:B0014050 name: SH22A_HUMAN-Phosphotyrosine216 def: "Protein SH22A_HUMAN with the residue 216 substituted with Phosphotyrosine" [UniProtKB:Q9NP31] xref: UniProtKB:Q9NP31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005476 ! SH22A_HUMAN [Term] id: CCO:B0014051 name: SH22A_HUMAN-Phosphotyrosine305 def: "Protein SH22A_HUMAN with the residue 305 substituted with Phosphotyrosine" [UniProtKB:Q9NP31] xref: UniProtKB:Q9NP31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005476 ! SH22A_HUMAN [Term] id: CCO:B0014052 name: SH3B4_HUMAN-Phosphoserine637 def: "Protein SH3B4_HUMAN with the residue 637 substituted with Phosphoserine" [UniProtKB:Q9P0V3] xref: UniProtKB:Q9P0V3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0002182 ! SH3B4_HUMAN [Term] id: CCO:B0014053 name: SH3G1_HUMAN-Phosphoserine288 def: "Protein SH3G1_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q99961] xref: UniProtKB:Q99961 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006310 ! SH3G1_HUMAN [Term] id: CCO:B0014054 name: SH3G2_HUMAN-Phosphoserine75 def: "Protein SH3G2_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q99962] xref: UniProtKB:Q99962 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:B0014055 name: SHC1_HUMAN-Phosphoserine36 def: "Protein SHC1_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P29353] comment: By similarity xref: UniProtKB:P29353 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001569 ! SHC1_HUMAN [Term] id: CCO:B0014056 name: SHC1_HUMAN-Phosphoserine139 def: "Protein SHC1_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:P29353] xref: UniProtKB:P29353 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001569 ! SHC1_HUMAN [Term] id: CCO:B0014057 name: SHC1_HUMAN-Phosphotyrosine349 def: "Protein SHC1_HUMAN with the residue 349 substituted with Phosphotyrosine" [UniProtKB:P29353] xref: UniProtKB:P29353 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001569 ! SHC1_HUMAN [Term] id: CCO:B0014058 name: SHC1_HUMAN-Phosphotyrosine350 def: "Protein SHC1_HUMAN with the residue 350 substituted with Phosphotyrosine" [UniProtKB:P29353] xref: UniProtKB:P29353 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001569 ! SHC1_HUMAN [Term] id: CCO:B0014059 name: SHC1_HUMAN-Phosphotyrosine427 def: "Protein SHC1_HUMAN with the residue 427 substituted with Phosphotyrosine" [UniProtKB:P29353] xref: UniProtKB:P29353 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001569 ! SHC1_HUMAN [Term] id: CCO:B0014060 name: SIN3A_HUMAN-Phosphoserine832 def: "Protein SIN3A_HUMAN with the residue 832 substituted with Phosphoserine" [UniProtKB:Q96ST3] xref: UniProtKB:Q96ST3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:B0014061 name: SIN3A_HUMAN-Phosphoserine860 def: "Protein SIN3A_HUMAN with the residue 860 substituted with Phosphoserine" [UniProtKB:Q96ST3] xref: UniProtKB:Q96ST3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:B0014062 name: SIN3A_HUMAN-Phosphoserine1112 def: "Protein SIN3A_HUMAN with the residue 1112 substituted with Phosphoserine" [UniProtKB:Q96ST3] xref: UniProtKB:Q96ST3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:B0014063 name: SIPA1_HUMAN-Phosphoserine74 def: "Protein SIPA1_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q96FS4] xref: UniProtKB:Q96FS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002039 ! SIPA1_HUMAN [Term] id: CCO:B0014064 name: SKIV2_HUMAN-Phosphoserine245 def: "Protein SKIV2_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:Q15477] xref: UniProtKB:Q15477 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005565 ! SKIV2_HUMAN [Term] id: CCO:B0014065 name: SKIV2_HUMAN-Phosphoserine256 def: "Protein SKIV2_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q15477] xref: UniProtKB:Q15477 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005565 ! SKIV2_HUMAN [Term] id: CCO:B0014066 name: SKIV2_HUMAN-Phosphoserine366 def: "Protein SKIV2_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q15477] xref: UniProtKB:Q15477 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005565 ! SKIV2_HUMAN [Term] id: CCO:B0014067 name: SKP2_HUMAN-Phosphoserine64 def: "Protein SKP2_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q13309] xref: UniProtKB:Q13309 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:B0014068 name: SMC1A_HUMAN-Phosphoserine358 def: "Protein SMC1A_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:Q14683] xref: UniProtKB:Q14683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:B0014069 name: SMC1A_HUMAN-Phosphoserine360 def: "Protein SMC1A_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q14683] xref: UniProtKB:Q14683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:B0014070 name: SMC1A_HUMAN-Phosphoserine951 def: "Protein SMC1A_HUMAN with the residue 951 substituted with Phosphoserine" [UniProtKB:Q14683] xref: UniProtKB:Q14683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000539 ! cohesin core heterodimer relationship: transformation_of CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:B0014071 name: SMC1A_HUMAN-Phosphoserine957 def: "Protein SMC1A_HUMAN with the residue 957 substituted with Phosphoserine" [UniProtKB:Q14683] comment: by ATM; xref: UniProtKB:Q14683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:B0014072 name: SMC1A_HUMAN-Phosphoserine962 def: "Protein SMC1A_HUMAN with the residue 962 substituted with Phosphoserine" [UniProtKB:Q14683] xref: UniProtKB:Q14683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:B0014073 name: SMC1A_HUMAN-Phosphoserine966 def: "Protein SMC1A_HUMAN with the residue 966 substituted with Phosphoserine" [UniProtKB:Q14683] comment: by ATM and ATR; xref: UniProtKB:Q14683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:B0014074 name: SMC1B_HUMAN-Phosphoserine882 def: "Protein SMC1B_HUMAN with the residue 882 substituted with Phosphoserine" [UniProtKB:Q8NDV3] xref: UniProtKB:Q8NDV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000127 ! lateral element relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001977 ! SMC1B_HUMAN [Term] id: CCO:B0014075 name: SMC1B_HUMAN-Phosphoserine883 def: "Protein SMC1B_HUMAN with the residue 883 substituted with Phosphoserine" [UniProtKB:Q8NDV3] xref: UniProtKB:Q8NDV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001977 ! SMC1B_HUMAN [Term] id: CCO:B0014076 name: SMC3_HUMAN-Phosphoserine787 def: "Protein SMC3_HUMAN with the residue 787 substituted with Phosphoserine" [UniProtKB:Q9UQE7] xref: UniProtKB:Q9UQE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0006133 ! dynein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000127 ! lateral element relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000538 ! cohesin complex relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0002243 ! SMC3_HUMAN [Term] id: CCO:B0014077 name: SMC3_HUMAN-Phosphoserine1013 def: "Protein SMC3_HUMAN with the residue 1013 substituted with Phosphoserine" [UniProtKB:Q9UQE7] comment: By similarity xref: UniProtKB:Q9UQE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002243 ! SMC3_HUMAN [Term] id: CCO:B0014078 name: SMC3_HUMAN-Phosphoserine1065 def: "Protein SMC3_HUMAN with the residue 1065 substituted with Phosphoserine" [UniProtKB:Q9UQE7] xref: UniProtKB:Q9UQE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002243 ! SMC3_HUMAN [Term] id: CCO:B0014079 name: SMC3_HUMAN-Phosphoserine1067 def: "Protein SMC3_HUMAN with the residue 1067 substituted with Phosphoserine" [UniProtKB:Q9UQE7] xref: UniProtKB:Q9UQE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002243 ! SMC3_HUMAN [Term] id: CCO:B0014080 name: SMC3_HUMAN-Phosphoserine1074 def: "Protein SMC3_HUMAN with the residue 1074 substituted with Phosphoserine" [UniProtKB:Q9UQE7] xref: UniProtKB:Q9UQE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002243 ! SMC3_HUMAN [Term] id: CCO:B0014081 name: SMC3_HUMAN-Phosphoserine1083 def: "Protein SMC3_HUMAN with the residue 1083 substituted with Phosphoserine" [UniProtKB:Q9UQE7] xref: UniProtKB:Q9UQE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002243 ! SMC3_HUMAN [Term] id: CCO:B0014082 name: SMC4_HUMAN-Phosphoserine22 def: "Protein SMC4_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:Q9NTJ3] xref: UniProtKB:Q9NTJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002168 ! SMC4_HUMAN [Term] id: CCO:B0014083 name: SMC4_HUMAN-Phosphoserine28 def: "Protein SMC4_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q9NTJ3] xref: UniProtKB:Q9NTJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002168 ! SMC4_HUMAN [Term] id: CCO:B0014084 name: SMC4_HUMAN-Phosphoserine41 def: "Protein SMC4_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q9NTJ3] xref: UniProtKB:Q9NTJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002168 ! SMC4_HUMAN [Term] id: CCO:B0014085 name: SMC4_HUMAN-Phosphoserine1056 def: "Protein SMC4_HUMAN with the residue 1056 substituted with Phosphoserine" [UniProtKB:Q9NTJ3] xref: UniProtKB:Q9NTJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000123 ! condensin complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002168 ! SMC4_HUMAN [Term] id: CCO:B0014095 name: SMCA2_HUMAN-N6-acetyllysine1551 def: "Protein SMCA2_HUMAN with the residue 1551 substituted with N6-acetyllysine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0014097 name: SMCA2_HUMAN-Phosphoserine1568 def: "Protein SMCA2_HUMAN with the residue 1568 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0014098 name: SMCA4_HUMAN-Phosphothreonine11 def: "Protein SMCA4_HUMAN with the residue 11 substituted with Phosphothreonine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014099 name: SMCA4_HUMAN-Phosphoserine610 def: "Protein SMCA4_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014100 name: SMCA4_HUMAN-Phosphoserine655 def: "Protein SMCA4_HUMAN with the residue 655 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014101 name: SMCA4_HUMAN-Phosphoserine657 def: "Protein SMCA4_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014102 name: SMCA4_HUMAN-Phosphoserine660 def: "Protein SMCA4_HUMAN with the residue 660 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014103 name: SMCA4_HUMAN-Phosphoserine662 def: "Protein SMCA4_HUMAN with the residue 662 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014104 name: SMCA4_HUMAN-Phosphoserine695 def: "Protein SMCA4_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014105 name: SMCA4_HUMAN-Phosphoserine721 def: "Protein SMCA4_HUMAN with the residue 721 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014106 name: SMCA4_HUMAN-Phosphoserine1382 def: "Protein SMCA4_HUMAN with the residue 1382 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014107 name: SMCA4_HUMAN-Phosphoserine1452 def: "Protein SMCA4_HUMAN with the residue 1452 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0014108 name: SMN_HUMAN-Phosphoserine4 def: "Protein SMN_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:Q16637] xref: UniProtKB:Q16637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006110 ! SMN_HUMAN [Term] id: CCO:B0014109 name: SMN_HUMAN-Phosphoserine5 def: "Protein SMN_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:Q16637] xref: UniProtKB:Q16637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006110 ! SMN_HUMAN [Term] id: CCO:B0014110 name: SMN_HUMAN-Phosphoserine8 def: "Protein SMN_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q16637] xref: UniProtKB:Q16637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006110 ! SMN_HUMAN [Term] id: CCO:B0014111 name: SMN_HUMAN-Phosphoserine28 def: "Protein SMN_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q16637] xref: UniProtKB:Q16637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006110 ! SMN_HUMAN [Term] id: CCO:B0014112 name: SMN_HUMAN-Phosphoserine31 def: "Protein SMN_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q16637] xref: UniProtKB:Q16637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006110 ! SMN_HUMAN [Term] id: CCO:B0014113 name: SMRC1_HUMAN-Phosphoserine310 def: "Protein SMRC1_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0014114 name: SMRC1_HUMAN-Phosphoserine319 def: "Protein SMRC1_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0014115 name: SMRC1_HUMAN-Phosphoserine328 def: "Protein SMRC1_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0014116 name: SMRC1_HUMAN-Phosphoserine330 def: "Protein SMRC1_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0014117 name: SMRC1_HUMAN-Phosphothreonine335 def: "Protein SMRC1_HUMAN with the residue 335 substituted with Phosphothreonine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0014118 name: SMRC1_HUMAN-Phosphothreonine337 def: "Protein SMRC1_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0014119 name: SMRC1_HUMAN-Phosphoserine357 def: "Protein SMRC1_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0014120 name: SMRC2_HUMAN-Phosphoserine283 def: "Protein SMRC2_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0014121 name: SMRC2_HUMAN-Phosphotyrosine296 def: "Protein SMRC2_HUMAN with the residue 296 substituted with Phosphotyrosine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0014122 name: SMRC2_HUMAN-Phosphoserine302 def: "Protein SMRC2_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0014123 name: SMRC2_HUMAN-Phosphoserine304 def: "Protein SMRC2_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0014124 name: SMRC2_HUMAN-Phosphothreonine322 def: "Protein SMRC2_HUMAN with the residue 322 substituted with Phosphothreonine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0014125 name: SMRC2_HUMAN-Phosphoserine347 def: "Protein SMRC2_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0014126 name: SMRD2_HUMAN-Phosphothreonine142 def: "Protein SMRD2_HUMAN with the residue 142 substituted with Phosphothreonine" [UniProtKB:Q92925] xref: UniProtKB:Q92925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005419 ! SMRD2_HUMAN [Term] id: CCO:B0014127 name: SMRD2_HUMAN-Phosphothreonine408 def: "Protein SMRD2_HUMAN with the residue 408 substituted with Phosphothreonine" [UniProtKB:Q92925] xref: UniProtKB:Q92925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005419 ! SMRD2_HUMAN [Term] id: CCO:B0014128 name: SN1L1_HUMAN-Phosphothreonine182 def: "Protein SN1L1_HUMAN with the residue 182 substituted with Phosphothreonine" [UniProtKB:P57059] xref: UniProtKB:P57059 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001680 ! SN1L1_HUMAN [Term] id: CCO:B0014129 name: SN1L1_HUMAN-Phosphoserine186 def: "Protein SN1L1_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:P57059] comment: By similarity xref: UniProtKB:P57059 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001680 ! SN1L1_HUMAN [Term] id: CCO:B0014130 name: SN1L1_HUMAN-Phosphothreonine460 def: "Protein SN1L1_HUMAN with the residue 460 substituted with Phosphothreonine" [UniProtKB:P57059] xref: UniProtKB:P57059 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001680 ! SN1L1_HUMAN [Term] id: CCO:B0014131 name: SN1L1_HUMAN-Phosphothreonine479 def: "Protein SN1L1_HUMAN with the residue 479 substituted with Phosphothreonine" [UniProtKB:P57059] xref: UniProtKB:P57059 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001680 ! SN1L1_HUMAN [Term] id: CCO:B0014132 name: SN1L1_HUMAN-Phosphoserine578 def: "Protein SN1L1_HUMAN with the residue 578 substituted with Phosphoserine" [UniProtKB:P57059] comment: By similarity xref: UniProtKB:P57059 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001680 ! SN1L1_HUMAN [Term] id: CCO:B0014133 name: SN1L2_HUMAN-Phosphothreonine175 def: "Protein SN1L2_HUMAN with the residue 175 substituted with Phosphothreonine" [UniProtKB:Q9H0K1] xref: UniProtKB:Q9H0K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005873 ! SN1L2_HUMAN [Term] id: CCO:B0014134 name: SN1L2_HUMAN-Phosphoserine179 def: "Protein SN1L2_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q9H0K1] comment: By similarity xref: UniProtKB:Q9H0K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005873 ! SN1L2_HUMAN [Term] id: CCO:B0014135 name: SN1L2_HUMAN-Phosphoserine587 def: "Protein SN1L2_HUMAN with the residue 587 substituted with Phosphoserine" [UniProtKB:Q9H0K1] xref: UniProtKB:Q9H0K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005873 ! SN1L2_HUMAN [Term] id: CCO:B0014136 name: SNF5_HUMAN-Phosphoserine129 def: "Protein SNF5_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q12824] xref: UniProtKB:Q12824 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001732 ! SNF5_HUMAN [Term] id: CCO:B0014137 name: SNIP1_HUMAN-Phosphoserine35 def: "Protein SNIP1_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0014138 name: SNIP1_HUMAN-Phosphoserine89 def: "Protein SNIP1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0014139 name: SNIP1_HUMAN-Phosphoserine91 def: "Protein SNIP1_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0014140 name: SNIP1_HUMAN-Phosphoserine153 def: "Protein SNIP1_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0014141 name: SNIP1_HUMAN-Phosphothreonine169 def: "Protein SNIP1_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0014142 name: SNIP1_HUMAN-Phosphoserine202 def: "Protein SNIP1_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0014143 name: SNIP1_HUMAN-Phosphoserine394 def: "Protein SNIP1_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q8TAD8] comment: By similarity xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0014144 name: SNUT1_HUMAN-Phosphothreonine392 def: "Protein SNUT1_HUMAN with the residue 392 substituted with Phosphothreonine" [UniProtKB:O43290] xref: UniProtKB:O43290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:B0014145 name: SNUT1_HUMAN-Phosphothreonine430 def: "Protein SNUT1_HUMAN with the residue 430 substituted with Phosphothreonine" [UniProtKB:O43290] xref: UniProtKB:O43290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:B0014146 name: SNUT1_HUMAN-Phosphoserine448 def: "Protein SNUT1_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:O43290] xref: UniProtKB:O43290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:B0014147 name: SNUT1_HUMAN-Phosphoserine591 def: "Protein SNUT1_HUMAN with the residue 591 substituted with Phosphoserine" [UniProtKB:O43290] xref: UniProtKB:O43290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:B0014148 name: SNUT1_HUMAN-Phosphoserine596 def: "Protein SNUT1_HUMAN with the residue 596 substituted with Phosphoserine" [UniProtKB:O43290] xref: UniProtKB:O43290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:B0014149 name: SNUT1_HUMAN-Phosphoserine598 def: "Protein SNUT1_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:O43290] xref: UniProtKB:O43290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:B0014150 name: SNUT1_HUMAN-Phosphothreonine695 def: "Protein SNUT1_HUMAN with the residue 695 substituted with Phosphothreonine" [UniProtKB:O43290] xref: UniProtKB:O43290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:B0014151 name: SNX9_HUMAN-Phosphoserine176 def: "Protein SNX9_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q9Y5X1] comment: By similarity xref: UniProtKB:Q9Y5X1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005559 ! SNX9_HUMAN [Term] id: CCO:B0014152 name: SOS1_HUMAN-Phosphoserine1043 def: "Protein SOS1_HUMAN with the residue 1043 substituted with Phosphoserine" [UniProtKB:Q07889] xref: UniProtKB:Q07889 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:B0014153 name: SOS1_HUMAN-Phosphoserine1078 def: "Protein SOS1_HUMAN with the residue 1078 substituted with Phosphoserine" [UniProtKB:Q07889] comment: By similarity xref: UniProtKB:Q07889 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:B0014154 name: SOS1_HUMAN-Phosphoserine1082 def: "Protein SOS1_HUMAN with the residue 1082 substituted with Phosphoserine" [UniProtKB:Q07889] xref: UniProtKB:Q07889 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:B0014155 name: SOS1_HUMAN-Phosphoserine1210 def: "Protein SOS1_HUMAN with the residue 1210 substituted with Phosphoserine" [UniProtKB:Q07889] xref: UniProtKB:Q07889 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:B0014156 name: SP1_HUMAN-Phosphoserine7 def: "Protein SP1_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:P08047] comment: By similarity xref: UniProtKB:P08047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005485 ! SP1_HUMAN [Term] id: CCO:B0014157 name: SP1_HUMAN-Phosphoserine59 def: "Protein SP1_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:P08047] xref: UniProtKB:P08047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005485 ! SP1_HUMAN [Term] id: CCO:B0014158 name: SPAG5_HUMAN-Phosphoserine12 def: "Protein SPAG5_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q96R06] comment: By similarity xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014159 name: SPAG5_HUMAN-Phosphoserine14 def: "Protein SPAG5_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q96R06] comment: By similarity xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014160 name: SPAG5_HUMAN-Phosphoserine62 def: "Protein SPAG5_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014161 name: SPAG5_HUMAN-Phosphoserine66 def: "Protein SPAG5_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014162 name: SPAG5_HUMAN-Phosphothreonine111 def: "Protein SPAG5_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014163 name: SPAG5_HUMAN-Phosphoserine135 def: "Protein SPAG5_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014164 name: SPAG5_HUMAN-Phosphoserine249 def: "Protein SPAG5_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000436 ! spindle microtubule relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014165 name: SPAG5_HUMAN-Phosphoserine334 def: "Protein SPAG5_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014166 name: SPAG5_HUMAN-Phosphoserine341 def: "Protein SPAG5_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014167 name: SPAG5_HUMAN-Phosphoserine353 def: "Protein SPAG5_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014168 name: SPAG5_HUMAN-Phosphoserine362 def: "Protein SPAG5_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014169 name: SPAG5_HUMAN-Phosphoserine364 def: "Protein SPAG5_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014170 name: SPAG5_HUMAN-Phosphothreonine377 def: "Protein SPAG5_HUMAN with the residue 377 substituted with Phosphothreonine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014171 name: SPAG5_HUMAN-Phosphothreonine389 def: "Protein SPAG5_HUMAN with the residue 389 substituted with Phosphothreonine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014172 name: SPAG5_HUMAN-Phosphoserine401 def: "Protein SPAG5_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014173 name: SPAG5_HUMAN-Phosphothreonine937 def: "Protein SPAG5_HUMAN with the residue 937 substituted with Phosphothreonine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0014174 name: SPC24_HUMAN-Phosphothreonine130 def: "Protein SPC24_HUMAN with the residue 130 substituted with Phosphothreonine" [UniProtKB:Q8NBT2] xref: UniProtKB:Q8NBT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001973 ! SPC24_HUMAN [Term] id: CCO:B0014175 name: SPG7_HUMAN-Nitrated tyrosine505 def: "Protein SPG7_HUMAN with the residue 505 substituted with Nitrated tyrosine" [UniProtKB:Q9UQ90] comment: By similarity xref: UniProtKB:Q9UQ90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: transformation_of CCO:B0006236 ! SPG7_HUMAN [Term] id: CCO:B0014176 name: SPIN1_HUMAN-Phosphoserine38 def: "Protein SPIN1_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:Q9Y657] xref: UniProtKB:Q9Y657 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002262 ! SPIN1_HUMAN [Term] id: CCO:B0014177 name: SPIN1_HUMAN-Phosphoserine39 def: "Protein SPIN1_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q9Y657] xref: UniProtKB:Q9Y657 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002262 ! SPIN1_HUMAN [Term] id: CCO:B0014178 name: SPT5H_HUMAN-Phosphoserine666 def: "Protein SPT5H_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:O00267] xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014179 name: SPT5H_HUMAN-dimethylarginine681 def: "Protein SPT5H_HUMAN with the residue 681 substituted with dimethylarginine" [UniProtKB:O00267] comment: by PRMT1; alternate; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014180 name: SPT5H_HUMAN-Omega-N-methylarginine681 def: "Protein SPT5H_HUMAN with the residue 681 substituted with Omega-N-methylarginine" [UniProtKB:O00267] comment: by PRMT1; alternate; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014181 name: SPT5H_HUMAN-dimethylarginine696 def: "Protein SPT5H_HUMAN with the residue 696 substituted with dimethylarginine" [UniProtKB:O00267] comment: by PRMT1; alternate; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014182 name: SPT5H_HUMAN-Omega-N-methylarginine696 def: "Protein SPT5H_HUMAN with the residue 696 substituted with Omega-N-methylarginine" [UniProtKB:O00267] comment: by PRMT1; alternate; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014183 name: SPT5H_HUMAN-dimethylarginine698 def: "Protein SPT5H_HUMAN with the residue 698 substituted with dimethylarginine" [UniProtKB:O00267] comment: by PRMT5; alternate; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014184 name: SPT5H_HUMAN-Omega-N-methylarginine698 def: "Protein SPT5H_HUMAN with the residue 698 substituted with Omega-N-methylarginine" [UniProtKB:O00267] comment: by PRMT1 and PRMT5; alternate; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014185 name: SPT5H_HUMAN-Phosphothreonine709 def: "Protein SPT5H_HUMAN with the residue 709 substituted with Phosphothreonine" [UniProtKB:O00267] xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014186 name: SPT5H_HUMAN-Phosphotyrosine717 def: "Protein SPT5H_HUMAN with the residue 717 substituted with Phosphotyrosine" [UniProtKB:O00267] xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014187 name: SPT5H_HUMAN-Phosphothreonine775 def: "Protein SPT5H_HUMAN with the residue 775 substituted with Phosphothreonine" [UniProtKB:O00267] comment: by CDK9; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001750 ! negative transcription elongation factor activity relationship: has_function CCO:F0001753 ! positive transcription elongation factor activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014188 name: SPT5H_HUMAN-Phosphothreonine784 def: "Protein SPT5H_HUMAN with the residue 784 substituted with Phosphothreonine" [UniProtKB:O00267] comment: by CDK9; xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014189 name: SPT5H_HUMAN-Phosphothreonine1034 def: "Protein SPT5H_HUMAN with the residue 1034 substituted with Phosphothreonine" [UniProtKB:O00267] xref: UniProtKB:O00267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001345 ! SPT5H_HUMAN [Term] id: CCO:B0014190 name: SPTB2_HUMAN-Phosphothreonine999 def: "Protein SPTB2_HUMAN with the residue 999 substituted with Phosphothreonine" [UniProtKB:Q01082] comment: By similarity xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014191 name: SPTB2_HUMAN-Phosphoserine1918 def: "Protein SPTB2_HUMAN with the residue 1918 substituted with Phosphoserine" [UniProtKB:Q01082] comment: By similarity xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014192 name: SPTB2_HUMAN-Phosphoserine2102 def: "Protein SPTB2_HUMAN with the residue 2102 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014193 name: SPTB2_HUMAN-Phosphoserine2115 def: "Protein SPTB2_HUMAN with the residue 2115 substituted with Phosphoserine" [UniProtKB:Q01082] comment: By similarity xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014194 name: SPTB2_HUMAN-Phosphoserine2128 def: "Protein SPTB2_HUMAN with the residue 2128 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014195 name: SPTB2_HUMAN-Phosphoserine2138 def: "Protein SPTB2_HUMAN with the residue 2138 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014196 name: SPTB2_HUMAN-Phosphoserine2165 def: "Protein SPTB2_HUMAN with the residue 2165 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014197 name: SPTB2_HUMAN-Phosphoserine2169 def: "Protein SPTB2_HUMAN with the residue 2169 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014198 name: SPTB2_HUMAN-Phosphothreonine2195 def: "Protein SPTB2_HUMAN with the residue 2195 substituted with Phosphothreonine" [UniProtKB:Q01082] comment: By similarity xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000529 ! spectrin relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0014199 name: SPTC2_HUMAN-Phosphoserine384 def: "Protein SPTC2_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:O15270] xref: UniProtKB:O15270 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006017 ! SPTC2_HUMAN [Term] id: CCO:B0014200 name: SPTC2_HUMAN-Phosphotyrosine387 def: "Protein SPTC2_HUMAN with the residue 387 substituted with Phosphotyrosine" [UniProtKB:O15270] xref: UniProtKB:O15270 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001122 ! serine C-palmitoyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003342 ! transferase activity, transferring nitrogenous groups relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0006017 ! SPTC2_HUMAN [Term] id: CCO:B0014201 name: SRBS1_HUMAN-Phosphoserine89 def: "Protein SRBS1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0014202 name: SRBS1_HUMAN-Phosphotyrosine134 def: "Protein SRBS1_HUMAN with the residue 134 substituted with Phosphotyrosine" [UniProtKB:Q9BX66] comment: By similarity xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0014203 name: SRBS1_HUMAN-Phosphothreonine349 def: "Protein SRBS1_HUMAN with the residue 349 substituted with Phosphothreonine" [UniProtKB:Q9BX66] comment: By similarity xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0014204 name: SRBS1_HUMAN-Phosphoserine481 def: "Protein SRBS1_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:Q9BX66] comment: By similarity xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0014205 name: SRBS1_HUMAN-Phosphothreonine497 def: "Protein SRBS1_HUMAN with the residue 497 substituted with Phosphothreonine" [UniProtKB:Q9BX66] comment: By similarity xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0014206 name: SRBS1_HUMAN-Phosphoserine556 def: "Protein SRBS1_HUMAN with the residue 556 substituted with Phosphoserine" [UniProtKB:Q9BX66] comment: By similarity xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0014207 name: SRBS1_HUMAN-Phosphoserine640 def: "Protein SRBS1_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q9BX66] comment: By similarity xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0014208 name: SRC_HUMAN-Phosphoserine17 def: "Protein SRC_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:P12931] xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0014209 name: SRC_HUMAN-Phosphoserine69 def: "Protein SRC_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:P12931] xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0014210 name: SRC_HUMAN-Phosphoserine75 def: "Protein SRC_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:P12931] xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0014211 name: SRC_HUMAN-Phosphotyrosine419 def: "Protein SRC_HUMAN with the residue 419 substituted with Phosphotyrosine" [UniProtKB:P12931] comment: by autocatalysis; xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0014212 name: SRC_HUMAN-Phosphotyrosine530 def: "Protein SRC_HUMAN with the residue 530 substituted with Phosphotyrosine" [UniProtKB:P12931] comment: by CSK; xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0014217 name: SSA27_HUMAN-Phosphoserine94 def: "Protein SSA27_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:O60232] xref: UniProtKB:O60232 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001405 ! SSA27_HUMAN [Term] id: CCO:B0014218 name: SSRA_HUMAN-Phosphoserine268 def: "Protein SSRA_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:P43307] xref: UniProtKB:P43307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001368 ! signal sequence binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0006163 ! SSRA_HUMAN [Term] id: CCO:B0014219 name: SSRP1_HUMAN-Phosphotyrosine311 def: "Protein SSRP1_HUMAN with the residue 311 substituted with Phosphotyrosine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014220 name: SSRP1_HUMAN-Phosphotyrosine441 def: "Protein SSRP1_HUMAN with the residue 441 substituted with Phosphotyrosine" [UniProtKB:Q08945] comment: By similarity xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014221 name: SSRP1_HUMAN-Phosphoserine444 def: "Protein SSRP1_HUMAN with the residue 444 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014222 name: SSRP1_HUMAN-Phosphoserine510 def: "Protein SSRP1_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q08945] comment: by CK2; Probable xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014223 name: SSRP1_HUMAN-Phosphotyrosine554 def: "Protein SSRP1_HUMAN with the residue 554 substituted with Phosphotyrosine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014224 name: SSRP1_HUMAN-Phosphoserine561 def: "Protein SSRP1_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014225 name: SSRP1_HUMAN-Phosphoserine657 def: "Protein SSRP1_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014226 name: SSRP1_HUMAN-Phosphoserine667 def: "Protein SSRP1_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014227 name: SSRP1_HUMAN-Phosphoserine668 def: "Protein SSRP1_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014228 name: SSRP1_HUMAN-Phosphoserine671 def: "Protein SSRP1_HUMAN with the residue 671 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014229 name: SSRP1_HUMAN-Phosphoserine672 def: "Protein SSRP1_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014230 name: SSRP1_HUMAN-Phosphoserine673 def: "Protein SSRP1_HUMAN with the residue 673 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014231 name: SSRP1_HUMAN-Phosphoserine688 def: "Protein SSRP1_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:Q08945] comment: by CK2; Probable xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0014232 name: ST5_HUMAN-Phosphoserine1011 def: "Protein ST5_HUMAN with the residue 1011 substituted with Phosphoserine" [UniProtKB:P78524] xref: UniProtKB:P78524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006063 ! ST5_HUMAN [Term] id: CCO:B0014233 name: ST5_HUMAN-Phosphoserine1013 def: "Protein ST5_HUMAN with the residue 1013 substituted with Phosphoserine" [UniProtKB:P78524] xref: UniProtKB:P78524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006063 ! ST5_HUMAN [Term] id: CCO:B0014234 name: ST5_HUMAN-Phosphoserine1015 def: "Protein ST5_HUMAN with the residue 1015 substituted with Phosphoserine" [UniProtKB:P78524] xref: UniProtKB:P78524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006063 ! ST5_HUMAN [Term] id: CCO:B0014235 name: STA5A_HUMAN-Phosphotyrosine694 def: "Protein STA5A_HUMAN with the residue 694 substituted with Phosphotyrosine" [UniProtKB:P42229] comment: by JAK; xref: UniProtKB:P42229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001609 ! STA5A_HUMAN [Term] id: CCO:B0014236 name: STA5A_HUMAN-Phosphoserine780 def: "Protein STA5A_HUMAN with the residue 780 substituted with Phosphoserine" [UniProtKB:P42229] comment: By similarity xref: UniProtKB:P42229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001609 ! STA5A_HUMAN [Term] id: CCO:B0014237 name: STA5B_HUMAN-Phosphoserine193 def: "Protein STA5B_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:P51692] xref: UniProtKB:P51692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001651 ! STA5B_HUMAN [Term] id: CCO:B0014238 name: STA5B_HUMAN-Phosphotyrosine699 def: "Protein STA5B_HUMAN with the residue 699 substituted with Phosphotyrosine" [UniProtKB:P51692] comment: by JAK; xref: UniProtKB:P51692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001651 ! STA5B_HUMAN [Term] id: CCO:B0014239 name: STAG1_HUMAN-Phosphoserine1069 def: "Protein STAG1_HUMAN with the residue 1069 substituted with Phosphoserine" [UniProtKB:Q8WVM7] comment: By similarity xref: UniProtKB:Q8WVM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002004 ! STAG1_HUMAN [Term] id: CCO:B0014240 name: STAG1_HUMAN-Phosphoserine1070 def: "Protein STAG1_HUMAN with the residue 1070 substituted with Phosphoserine" [UniProtKB:Q8WVM7] comment: By similarity xref: UniProtKB:Q8WVM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002004 ! STAG1_HUMAN [Term] id: CCO:B0014241 name: STAG2_HUMAN-Phosphoserine1061 def: "Protein STAG2_HUMAN with the residue 1061 substituted with Phosphoserine" [UniProtKB:Q8N3U4] xref: UniProtKB:Q8N3U4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001962 ! STAG2_HUMAN [Term] id: CCO:B0014242 name: STAG2_HUMAN-Phosphothreonine1160 def: "Protein STAG2_HUMAN with the residue 1160 substituted with Phosphothreonine" [UniProtKB:Q8N3U4] comment: By similarity xref: UniProtKB:Q8N3U4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001962 ! STAG2_HUMAN [Term] id: CCO:B0014243 name: STAT1_HUMAN-Phosphotyrosine701 def: "Protein STAT1_HUMAN with the residue 701 substituted with Phosphotyrosine" [UniProtKB:P42224] comment: by JAK; xref: UniProtKB:P42224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001608 ! STAT1_HUMAN [Term] id: CCO:B0014244 name: STAT1_HUMAN-Phosphoserine727 def: "Protein STAT1_HUMAN with the residue 727 substituted with Phosphoserine" [UniProtKB:P42224] xref: UniProtKB:P42224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001608 ! STAT1_HUMAN [Term] id: CCO:B0014245 name: STAT3_HUMAN-Phosphoserine691 def: "Protein STAT3_HUMAN with the residue 691 substituted with Phosphoserine" [UniProtKB:P40763] xref: UniProtKB:P40763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:B0014246 name: STAT3_HUMAN-Phosphotyrosine705 def: "Protein STAT3_HUMAN with the residue 705 substituted with Phosphotyrosine" [UniProtKB:P40763] xref: UniProtKB:P40763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:B0014247 name: STAT3_HUMAN-Phosphoserine727 def: "Protein STAT3_HUMAN with the residue 727 substituted with Phosphoserine" [UniProtKB:P40763] xref: UniProtKB:P40763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:B0014248 name: STC2_HUMAN-Phosphothreonine28 def: "Protein STC2_HUMAN with the residue 28 substituted with Phosphothreonine" [UniProtKB:O76061] xref: UniProtKB:O76061 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0006237 ! STC2_HUMAN [Term] id: CCO:B0014249 name: STEA3_HUMAN-Phosphoserine20 def: "Protein STEA3_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q658P3] comment: By similarity xref: UniProtKB:Q658P3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001903 ! STEA3_HUMAN [Term] id: CCO:B0014250 name: STK11_HUMAN-Phosphoserine31 def: "Protein STK11_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q15831] comment: By similarity xref: UniProtKB:Q15831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001814 ! STK11_HUMAN [Term] id: CCO:B0014251 name: STK11_HUMAN-Phosphothreonine336 def: "Protein STK11_HUMAN with the residue 336 substituted with Phosphothreonine" [UniProtKB:Q15831] comment: by autocatalysis; xref: UniProtKB:Q15831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001814 ! STK11_HUMAN [Term] id: CCO:B0014252 name: STK11_HUMAN-Phosphothreonine363 def: "Protein STK11_HUMAN with the residue 363 substituted with Phosphothreonine" [UniProtKB:Q15831] comment: by autocatalysis; xref: UniProtKB:Q15831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001814 ! STK11_HUMAN [Term] id: CCO:B0014253 name: STK11_HUMAN-Phosphoserine428 def: "Protein STK11_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q15831] comment: by PKA; Potential xref: UniProtKB:Q15831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001814 ! STK11_HUMAN [Term] id: CCO:B0014254 name: STK4_HUMAN-Phosphothreonine183 def: "Protein STK4_HUMAN with the residue 183 substituted with Phosphothreonine" [UniProtKB:Q13043] comment: by autocatalysis; xref: UniProtKB:Q13043 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005702 ! STK4_HUMAN [Term] id: CCO:B0014255 name: STK4_HUMAN-Phosphoserine320 def: "Protein STK4_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q13043] xref: UniProtKB:Q13043 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005702 ! STK4_HUMAN [Term] id: CCO:B0014256 name: STK4_HUMAN-Phosphotyrosine433 def: "Protein STK4_HUMAN with the residue 433 substituted with Phosphotyrosine" [UniProtKB:Q13043] xref: UniProtKB:Q13043 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005702 ! STK4_HUMAN [Term] id: CCO:B0014257 name: STK6_HUMAN-Phosphoserine369 def: "Protein STK6_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:O14965] xref: UniProtKB:O14965 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001363 ! STK6_HUMAN [Term] id: CCO:B0014258 name: STMN1_HUMAN-N-acetylalanine2 def: "Protein STMN1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P16949] xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014259 name: STMN1_HUMAN-Phosphoserine16 def: "Protein STMN1_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:P16949] xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014260 name: STMN1_HUMAN-Phosphoserine25 def: "Protein STMN1_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:P16949] comment: by CDC2 and MAPK; xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014261 name: STMN1_HUMAN-Phosphoserine28 def: "Protein STMN1_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:P16949] xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014262 name: STMN1_HUMAN-Phosphoserine38 def: "Protein STMN1_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:P16949] comment: by CDC2; xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014263 name: STMN1_HUMAN-Phosphoserine46 def: "Protein STMN1_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:P16949] comment: By similarity xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014264 name: STMN1_HUMAN-Phosphoserine63 def: "Protein STMN1_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:P16949] comment: by PKA; xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014265 name: STMN1_HUMAN-Phosphothreonine146 def: "Protein STMN1_HUMAN with the residue 146 substituted with Phosphothreonine" [UniProtKB:P16949] xref: UniProtKB:P16949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001528 ! STMN1_HUMAN [Term] id: CCO:B0014266 name: STRAD_HUMAN-Phosphothreonine329 def: "Protein STRAD_HUMAN with the residue 329 substituted with Phosphothreonine" [UniProtKB:Q7RTN6] comment: by STK11; xref: UniProtKB:Q7RTN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:B0014267 name: STRAD_HUMAN-Phosphothreonine419 def: "Protein STRAD_HUMAN with the residue 419 substituted with Phosphothreonine" [UniProtKB:Q7RTN6] comment: by STK11; xref: UniProtKB:Q7RTN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:B0014268 name: STRN3_HUMAN-Phosphoserine229 def: "Protein STRN3_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:Q13033] xref: UniProtKB:Q13033 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001737 ! STRN3_HUMAN [Term] id: CCO:B0014269 name: STRN4_HUMAN-Phosphoserine206 def: "Protein STRN4_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q9NRL3] comment: By similarity xref: UniProtKB:Q9NRL3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006352 ! STRN4_HUMAN [Term] id: CCO:B0014270 name: SUGT1_HUMAN-Phosphothreonine265 def: "Protein SUGT1_HUMAN with the residue 265 substituted with Phosphothreonine" [UniProtKB:Q9Y2Z0] xref: UniProtKB:Q9Y2Z0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002252 ! SUGT1_HUMAN [Term] id: CCO:B0014271 name: SUGT1_HUMAN-Phosphotyrosine317 def: "Protein SUGT1_HUMAN with the residue 317 substituted with Phosphotyrosine" [UniProtKB:Q9Y2Z0] xref: UniProtKB:Q9Y2Z0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002252 ! SUGT1_HUMAN [Term] id: CCO:B0014272 name: SUMO1_HUMAN-Phosphoserine2 def: "Protein SUMO1_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P63165] xref: UniProtKB:P63165 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000820 ! nuclear speck relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:B0014273 name: SUV91_HUMAN-Phosphoserine391 def: "Protein SUV91_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:O43463] xref: UniProtKB:O43463 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001391 ! SUV91_HUMAN [Term] id: CCO:B0014274 name: SYK_HUMAN-Phosphoserine596 def: "Protein SYK_HUMAN with the residue 596 substituted with Phosphoserine" [UniProtKB:Q15046] comment: By similarity xref: UniProtKB:Q15046 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001182 ! lysine-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006279 ! SYK_HUMAN [Term] id: CCO:B0014275 name: T2FA_HUMAN-Phosphoserine217 def: "Protein T2FA_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014276 name: T2FA_HUMAN-Phosphoserine218 def: "Protein T2FA_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014277 name: T2FA_HUMAN-Phosphoserine221 def: "Protein T2FA_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014278 name: T2FA_HUMAN-Phosphoserine224 def: "Protein T2FA_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014279 name: T2FA_HUMAN-Phosphoserine305 def: "Protein T2FA_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014280 name: T2FA_HUMAN-Phosphoserine307 def: "Protein T2FA_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000278 ! transcription factor TFIIF complex relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014281 name: T2FA_HUMAN-Phosphoserine308 def: "Protein T2FA_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014282 name: T2FA_HUMAN-Phosphoserine311 def: "Protein T2FA_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014283 name: T2FA_HUMAN-Phosphoserine342 def: "Protein T2FA_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014284 name: T2FA_HUMAN-Phosphoserine345 def: "Protein T2FA_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014285 name: T2FA_HUMAN-Phosphoserine347 def: "Protein T2FA_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014286 name: T2FA_HUMAN-Phosphoserine348 def: "Protein T2FA_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014287 name: T2FA_HUMAN-Phosphoserine351 def: "Protein T2FA_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014288 name: T2FA_HUMAN-Phosphoserine355 def: "Protein T2FA_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014289 name: T2FA_HUMAN-Phosphoserine385 def: "Protein T2FA_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014290 name: T2FA_HUMAN-Phosphothreonine389 def: "Protein T2FA_HUMAN with the residue 389 substituted with Phosphothreonine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014291 name: T2FA_HUMAN-Phosphoserine433 def: "Protein T2FA_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:P35269] xref: UniProtKB:P35269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:B0014292 name: TAB2_HUMAN-Phosphoserine450 def: "Protein TAB2_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q9NYJ8] comment: By similarity xref: UniProtKB:Q9NYJ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:B0014293 name: TACC1_HUMAN-Phosphoserine44 def: "Protein TACC1_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:O75410] xref: UniProtKB:O75410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001425 ! TACC1_HUMAN [Term] id: CCO:B0014294 name: TACC1_HUMAN-Phosphoserine50 def: "Protein TACC1_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:O75410] xref: UniProtKB:O75410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001425 ! TACC1_HUMAN [Term] id: CCO:B0014295 name: TACC1_HUMAN-Phosphoserine52 def: "Protein TACC1_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:O75410] xref: UniProtKB:O75410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001425 ! TACC1_HUMAN [Term] id: CCO:B0014296 name: TACC1_HUMAN-Phosphoserine54 def: "Protein TACC1_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:O75410] xref: UniProtKB:O75410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001425 ! TACC1_HUMAN [Term] id: CCO:B0014297 name: TACC1_HUMAN-Phosphoserine55 def: "Protein TACC1_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:O75410] xref: UniProtKB:O75410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001425 ! TACC1_HUMAN [Term] id: CCO:B0014298 name: TACC1_HUMAN-Phosphoserine57 def: "Protein TACC1_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:O75410] xref: UniProtKB:O75410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001425 ! TACC1_HUMAN [Term] id: CCO:B0014299 name: TACC1_HUMAN-Phosphotyrosine533 def: "Protein TACC1_HUMAN with the residue 533 substituted with Phosphotyrosine" [UniProtKB:O75410] xref: UniProtKB:O75410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001425 ! TACC1_HUMAN [Term] id: CCO:B0014300 name: TACC2_HUMAN-Phosphoserine1946 def: "Protein TACC2_HUMAN with the residue 1946 substituted with Phosphoserine" [UniProtKB:O95359] comment: By similarity xref: UniProtKB:O95359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006276 ! TACC2_HUMAN [Term] id: CCO:B0014301 name: TACC2_HUMAN-Phosphoserine1949 def: "Protein TACC2_HUMAN with the residue 1949 substituted with Phosphoserine" [UniProtKB:O95359] comment: By similarity xref: UniProtKB:O95359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006276 ! TACC2_HUMAN [Term] id: CCO:B0014302 name: TACC2_HUMAN-Phosphoserine2256 def: "Protein TACC2_HUMAN with the residue 2256 substituted with Phosphoserine" [UniProtKB:O95359] xref: UniProtKB:O95359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006276 ! TACC2_HUMAN [Term] id: CCO:B0014303 name: TACC2_HUMAN-Phosphoserine2317 def: "Protein TACC2_HUMAN with the residue 2317 substituted with Phosphoserine" [UniProtKB:O95359] comment: By similarity xref: UniProtKB:O95359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006276 ! TACC2_HUMAN [Term] id: CCO:B0014304 name: TACC2_HUMAN-Phosphoserine2512 def: "Protein TACC2_HUMAN with the residue 2512 substituted with Phosphoserine" [UniProtKB:O95359] xref: UniProtKB:O95359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005585 ! nuclear hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0006276 ! TACC2_HUMAN [Term] id: CCO:B0014305 name: TAF1_HUMAN-Phosphoserine137 def: "Protein TAF1_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:P21675] comment: by autocatalysis; xref: UniProtKB:P21675 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001543 ! TAF1_HUMAN [Term] id: CCO:B0014306 name: TAF1_HUMAN-Phosphoserine307 def: "Protein TAF1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:P21675] comment: by autocatalysis; xref: UniProtKB:P21675 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001543 ! TAF1_HUMAN [Term] id: CCO:B0014307 name: TAF9_HUMAN-Phosphoserine85 def: "Protein TAF9_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q16594] xref: UniProtKB:Q16594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:B0014308 name: TBA1A_HUMAN-Phosphoserine6 def: "Protein TBA1A_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q71U36] comment: By similarity xref: UniProtKB:Q71U36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:B0014309 name: TBA1A_HUMAN-Phosphotyrosine272 def: "Protein TBA1A_HUMAN with the residue 272 substituted with Phosphotyrosine" [UniProtKB:Q71U36] comment: By similarity xref: UniProtKB:Q71U36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:B0014310 name: TBA1A_HUMAN-Phosphoserine439 def: "Protein TBA1A_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:Q71U36] xref: UniProtKB:Q71U36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:B0014311 name: TBA1B_HUMAN-Phosphotyrosine272 def: "Protein TBA1B_HUMAN with the residue 272 substituted with Phosphotyrosine" [UniProtKB:P68363] xref: UniProtKB:P68363 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0024588 ! TBA1B_HUMAN [Term] id: CCO:B0014312 name: TBA4A_HUMAN-Phosphoserine6 def: "Protein TBA4A_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:P68366] comment: By similarity xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0014313 name: TBA4A_HUMAN-Phosphotyrosine161 def: "Protein TBA4A_HUMAN with the residue 161 substituted with Phosphotyrosine" [UniProtKB:P68366] xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0014314 name: TBA4A_HUMAN-Phosphotyrosine272 def: "Protein TBA4A_HUMAN with the residue 272 substituted with Phosphotyrosine" [UniProtKB:P68366] xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0014315 name: TBB4_HUMAN-Phosphothreonine290 def: "Protein TBB4_HUMAN with the residue 290 substituted with Phosphothreonine" [UniProtKB:P04350] xref: UniProtKB:P04350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006167 ! TBB4_HUMAN [Term] id: CCO:B0014316 name: TBB4_HUMAN-Phosphothreonine366 def: "Protein TBB4_HUMAN with the residue 366 substituted with Phosphothreonine" [UniProtKB:P04350] comment: By similarity xref: UniProtKB:P04350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006167 ! TBB4_HUMAN [Term] id: CCO:B0014317 name: TBB5_HUMAN-Phosphotyrosine36 def: "Protein TBB5_HUMAN with the residue 36 substituted with Phosphotyrosine" [UniProtKB:P07437] xref: UniProtKB:P07437 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0005648 ! MHC class I protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0005727 ! TBB5_HUMAN [Term] id: CCO:B0014318 name: TBK1_HUMAN-Phosphoserine172 def: "Protein TBK1_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q9UHD2] comment: by autocatalysis; xref: UniProtKB:Q9UHD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:B0014319 name: TBL1R_HUMAN-Phosphoserine119 def: "Protein TBL1R_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q9BZK7] xref: UniProtKB:Q9BZK7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006041 ! TBL1R_HUMAN [Term] id: CCO:B0014320 name: TBRG4_HUMAN-Phosphothreonine65 def: "Protein TBRG4_HUMAN with the residue 65 substituted with Phosphothreonine" [UniProtKB:Q969Z0] xref: UniProtKB:Q969Z0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002030 ! TBRG4_HUMAN [Term] id: CCO:B0014321 name: TBX3_HUMAN-Phosphoserine375 def: "Protein TBX3_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:O15119] comment: By similarity xref: UniProtKB:O15119 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001365 ! TBX3_HUMAN [Term] id: CCO:B0014322 name: TBX3_HUMAN-Phosphoserine456 def: "Protein TBX3_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:O15119] xref: UniProtKB:O15119 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001365 ! TBX3_HUMAN [Term] id: CCO:B0014323 name: TCPB_HUMAN-N-acetylalanine2 def: "Protein TCPB_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P78371] xref: UniProtKB:P78371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000400 ! chaperonin-containing T-complex relationship: transformation_of CCO:B0001700 ! TCPB_HUMAN [Term] id: CCO:B0014324 name: TCPG_HUMAN-Phosphothreonine254 def: "Protein TCPG_HUMAN with the residue 254 substituted with Phosphothreonine" [UniProtKB:P49368] xref: UniProtKB:P49368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005253 ! TCPG_HUMAN [Term] id: CCO:B0014325 name: TCPH_HUMAN-N-acetylmethionine1 def: "Protein TCPH_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q99832] xref: UniProtKB:Q99832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002089 ! TCPH_HUMAN [Term] id: CCO:B0014326 name: TCRG1_HUMAN-Phosphoserine481 def: "Protein TCRG1_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:O14776] xref: UniProtKB:O14776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005396 ! TCRG1_HUMAN [Term] id: CCO:B0014327 name: TCRG1_HUMAN-Phosphothreonine489 def: "Protein TCRG1_HUMAN with the residue 489 substituted with Phosphothreonine" [UniProtKB:O14776] xref: UniProtKB:O14776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005396 ! TCRG1_HUMAN [Term] id: CCO:B0014328 name: TE2IP_HUMAN-Phosphoserine154 def: "Protein TE2IP_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q9NYB0] xref: UniProtKB:Q9NYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_function CCO:F0005790 ! single-stranded telomeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:B0014329 name: TE2IP_HUMAN-Phosphoserine156 def: "Protein TE2IP_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q9NYB0] xref: UniProtKB:Q9NYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:B0014330 name: TE2IP_HUMAN-Phosphoserine203 def: "Protein TE2IP_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q9NYB0] xref: UniProtKB:Q9NYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:B0014331 name: TE2IP_HUMAN-Phosphoserine206 def: "Protein TE2IP_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q9NYB0] xref: UniProtKB:Q9NYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:B0014332 name: TERF1_HUMAN-Phosphoserine11 def: "Protein TERF1_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P54274] xref: UniProtKB:P54274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001667 ! TERF1_HUMAN [Term] id: CCO:B0014333 name: TERF1_HUMAN-Phosphoserine219 def: "Protein TERF1_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:P54274] comment: by ATM; xref: UniProtKB:P54274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001667 ! TERF1_HUMAN [Term] id: CCO:B0014334 name: TERF2_HUMAN-Phosphoserine323 def: "Protein TERF2_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:Q15554] xref: UniProtKB:Q15554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001810 ! TERF2_HUMAN [Term] id: CCO:B0014335 name: TERF2_HUMAN-Phosphoserine368 def: "Protein TERF2_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q15554] xref: UniProtKB:Q15554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001810 ! TERF2_HUMAN [Term] id: CCO:B0014336 name: TERF2_HUMAN-Phosphoserine380 def: "Protein TERF2_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q15554] xref: UniProtKB:Q15554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_function CCO:F0005790 ! single-stranded telomeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0001810 ! TERF2_HUMAN [Term] id: CCO:B0014337 name: TF3C1_HUMAN-Phosphoserine739 def: "Protein TF3C1_HUMAN with the residue 739 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014338 name: TF3C1_HUMAN-Phosphoserine751 def: "Protein TF3C1_HUMAN with the residue 751 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014339 name: TF3C1_HUMAN-Phosphoserine1062 def: "Protein TF3C1_HUMAN with the residue 1062 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014340 name: TF3C1_HUMAN-Phosphoserine1068 def: "Protein TF3C1_HUMAN with the residue 1068 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014341 name: TF3C1_HUMAN-Phosphoserine1653 def: "Protein TF3C1_HUMAN with the residue 1653 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014342 name: TF3C1_HUMAN-Phosphoserine1865 def: "Protein TF3C1_HUMAN with the residue 1865 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014343 name: TF3C1_HUMAN-Phosphoserine1868 def: "Protein TF3C1_HUMAN with the residue 1868 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014344 name: TF3C1_HUMAN-Phosphoserine1969 def: "Protein TF3C1_HUMAN with the residue 1969 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0014345 name: TF65_HUMAN-Phosphoserine276 def: "Protein TF65_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q04206] comment: by RPS6KA4 and RPS6KA5; xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0014346 name: TFDP1_HUMAN-Phosphoserine23 def: "Protein TFDP1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q14186] xref: UniProtKB:Q14186 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001776 ! TFDP1_HUMAN [Term] id: CCO:B0014347 name: TFDP2_HUMAN-Phosphoserine24 def: "Protein TFDP2_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q14188] comment: by CDK2; Potential xref: UniProtKB:Q14188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001777 ! TFDP2_HUMAN [Term] id: CCO:B0014348 name: TFDP2_HUMAN-Phosphoserine42 def: "Protein TFDP2_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q14188] comment: by CDK2; Potential xref: UniProtKB:Q14188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001777 ! TFDP2_HUMAN [Term] id: CCO:B0014349 name: TGFR2_HUMAN-Phosphoserine548 def: "Protein TGFR2_HUMAN with the residue 548 substituted with Phosphoserine" [UniProtKB:P37173] xref: UniProtKB:P37173 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001356 ! transforming growth factor beta receptor activity, type II relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001751 ! receptor complex relationship: transformation_of CCO:B0005542 ! TGFR2_HUMAN [Term] id: CCO:B0014350 name: THIO_HUMAN-N6-acetyllysine94 def: "Protein THIO_HUMAN with the residue 94 substituted with N6-acetyllysine" [UniProtKB:P10599] xref: UniProtKB:P10599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:B0014351 name: THIO_HUMAN-Phosphothreonine100 def: "Protein THIO_HUMAN with the residue 100 substituted with Phosphothreonine" [UniProtKB:P10599] xref: UniProtKB:P10599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:B0014352 name: THRB_HUMAN-4-carboxyglutamate49 def: "Protein THRB_HUMAN with the residue 49 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014353 name: THRB_HUMAN-4-carboxyglutamate50 def: "Protein THRB_HUMAN with the residue 50 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014354 name: THRB_HUMAN-4-carboxyglutamate57 def: "Protein THRB_HUMAN with the residue 57 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014355 name: THRB_HUMAN-4-carboxyglutamate59 def: "Protein THRB_HUMAN with the residue 59 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000334 ! thrombin activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014356 name: THRB_HUMAN-4-carboxyglutamate62 def: "Protein THRB_HUMAN with the residue 62 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014357 name: THRB_HUMAN-4-carboxyglutamate63 def: "Protein THRB_HUMAN with the residue 63 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014358 name: THRB_HUMAN-4-carboxyglutamate68 def: "Protein THRB_HUMAN with the residue 68 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014359 name: THRB_HUMAN-4-carboxyglutamate69 def: "Protein THRB_HUMAN with the residue 69 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014360 name: THRB_HUMAN-4-carboxyglutamate72 def: "Protein THRB_HUMAN with the residue 72 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014361 name: THRB_HUMAN-4-carboxyglutamate75 def: "Protein THRB_HUMAN with the residue 75 substituted with 4-carboxyglutamate" [UniProtKB:P00734] xref: UniProtKB:P00734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001464 ! THRB_HUMAN [Term] id: CCO:B0014362 name: TIF1B_HUMAN-N-acetylalanine2 def: "Protein TIF1B_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014363 name: TIF1B_HUMAN-Phosphoserine19 def: "Protein TIF1B_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014364 name: TIF1B_HUMAN-Phosphoserine50 def: "Protein TIF1B_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014365 name: TIF1B_HUMAN-Phosphoserine440 def: "Protein TIF1B_HUMAN with the residue 440 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014366 name: TIF1B_HUMAN-Phosphoserine466 def: "Protein TIF1B_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014367 name: TIF1B_HUMAN-Phosphoserine471 def: "Protein TIF1B_HUMAN with the residue 471 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014368 name: TIF1B_HUMAN-Phosphoserine473 def: "Protein TIF1B_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014369 name: TIF1B_HUMAN-Phosphoserine501 def: "Protein TIF1B_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014370 name: TIF1B_HUMAN-Phosphothreonine541 def: "Protein TIF1B_HUMAN with the residue 541 substituted with Phosphothreonine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014371 name: TIF1B_HUMAN-Phosphoserine594 def: "Protein TIF1B_HUMAN with the residue 594 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014372 name: TIF1B_HUMAN-Phosphoserine681 def: "Protein TIF1B_HUMAN with the residue 681 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014373 name: TIF1B_HUMAN-Phosphoserine683 def: "Protein TIF1B_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014374 name: TIF1B_HUMAN-Phosphoserine757 def: "Protein TIF1B_HUMAN with the residue 757 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014375 name: TIF1B_HUMAN-Phosphoserine824 def: "Protein TIF1B_HUMAN with the residue 824 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0014376 name: TIM_HUMAN-Phosphothreonine1089 def: "Protein TIM_HUMAN with the residue 1089 substituted with Phosphothreonine" [UniProtKB:Q9UNS1] xref: UniProtKB:Q9UNS1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002235 ! TIM_HUMAN [Term] id: CCO:B0014377 name: TIM_HUMAN-Phosphoserine1173 def: "Protein TIM_HUMAN with the residue 1173 substituted with Phosphoserine" [UniProtKB:Q9UNS1] xref: UniProtKB:Q9UNS1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002235 ! TIM_HUMAN [Term] id: CCO:B0014378 name: TIP60_HUMAN-Phosphoserine86 def: "Protein TIP60_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q92993] xref: UniProtKB:Q92993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001626 ! NuA4 histone acetyltransferase complex relationship: transformation_of CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:B0014379 name: TIP60_HUMAN-Phosphoserine90 def: "Protein TIP60_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:Q92993] comment: by CDC2; xref: UniProtKB:Q92993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:B0014380 name: TIPIN_HUMAN-Phosphoserine222 def: "Protein TIPIN_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q9BVW5] xref: UniProtKB:Q9BVW5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002104 ! TIPIN_HUMAN [Term] id: CCO:B0014381 name: TITIN_HUMAN-Phosphoserine33938 def: "Protein TITIN_HUMAN with the residue 33938 substituted with Phosphoserine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0014382 name: TITIN_HUMAN-Phosphoserine33942 def: "Protein TITIN_HUMAN with the residue 33942 substituted with Phosphoserine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0014383 name: TITIN_HUMAN-Phosphoserine9203 def: "Protein TITIN_HUMAN with the residue 9203 substituted with Phosphoserine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003516 ! myosin binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008092 ! alpha-actinin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000932 ! myofibril relationship: located_in CCO:C0000933 ! sarcomere relationship: located_in CCO:C0000934 ! Z disc relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0014384 name: TITIN_HUMAN-Phosphothreonine9207 def: "Protein TITIN_HUMAN with the residue 9207 substituted with Phosphothreonine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0014385 name: TITIN_HUMAN-Phosphoserine22525 def: "Protein TITIN_HUMAN with the residue 22525 substituted with Phosphoserine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0014386 name: TITIN_HUMAN-Phosphoserine22534 def: "Protein TITIN_HUMAN with the residue 22534 substituted with Phosphoserine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0014387 name: TITIN_HUMAN-Phosphotyrosine32341 def: "Protein TITIN_HUMAN with the residue 32341 substituted with Phosphotyrosine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0014388 name: TKNK_HUMAN-Methionine amide90 def: "Protein TKNK_HUMAN with the residue 90 substituted with Methionine amide" [UniProtKB:Q9UHF0] comment: By similarity xref: UniProtKB:Q9UHF0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0006242 ! TKNK_HUMAN [Term] id: CCO:B0014389 name: TLE1_HUMAN-Phosphoserine239 def: "Protein TLE1_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q04724] comment: by CK2; Potential xref: UniProtKB:Q04724 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:B0014390 name: TLE1_HUMAN-Phosphoserine259 def: "Protein TLE1_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:Q04724] comment: by CDC2; Potential xref: UniProtKB:Q04724 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:B0014391 name: TLE1_HUMAN-Phosphoserine263 def: "Protein TLE1_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q04724] comment: by CDC2; Potential xref: UniProtKB:Q04724 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:B0014392 name: TLE1_HUMAN-Phosphoserine267 def: "Protein TLE1_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q04724] comment: by CDC2; Potential xref: UniProtKB:Q04724 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:B0014393 name: TLE1_HUMAN-Phosphoserine284 def: "Protein TLE1_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q04724] comment: By similarity xref: UniProtKB:Q04724 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:B0014394 name: TLE2_HUMAN-Phosphoserine228 def: "Protein TLE2_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q04725] comment: by CK2; Potential xref: UniProtKB:Q04725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:B0014395 name: TLE2_HUMAN-Phosphoserine249 def: "Protein TLE2_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q04725] comment: by CDC2; Potential xref: UniProtKB:Q04725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:B0014396 name: TLE2_HUMAN-Phosphothreonine253 def: "Protein TLE2_HUMAN with the residue 253 substituted with Phosphothreonine" [UniProtKB:Q04725] comment: by CDC2; Potential xref: UniProtKB:Q04725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:B0014397 name: TLE3_HUMAN-Phosphoserine201 def: "Protein TLE3_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014398 name: TLE3_HUMAN-Phosphoserine203 def: "Protein TLE3_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014399 name: TLE3_HUMAN-Phosphoserine207 def: "Protein TLE3_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014400 name: TLE3_HUMAN-Phosphoserine217 def: "Protein TLE3_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014401 name: TLE3_HUMAN-Phosphoserine240 def: "Protein TLE3_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014402 name: TLE3_HUMAN-Phosphoserine245 def: "Protein TLE3_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014403 name: TLE3_HUMAN-Phosphothreonine259 def: "Protein TLE3_HUMAN with the residue 259 substituted with Phosphothreonine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014404 name: TLE3_HUMAN-Phosphoserine263 def: "Protein TLE3_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014405 name: TLE3_HUMAN-Phosphoserine267 def: "Protein TLE3_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014406 name: TLE3_HUMAN-Phosphoserine286 def: "Protein TLE3_HUMAN with the residue 286 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014407 name: TLE3_HUMAN-Phosphothreonine328 def: "Protein TLE3_HUMAN with the residue 328 substituted with Phosphothreonine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014408 name: TLE3_HUMAN-Phosphothreonine334 def: "Protein TLE3_HUMAN with the residue 334 substituted with Phosphothreonine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0014409 name: TLK1_HUMAN-Phosphoserine159 def: "Protein TLK1_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:Q9UKI8] xref: UniProtKB:Q9UKI8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002220 ! TLK1_HUMAN [Term] id: CCO:B0014410 name: TLK1_HUMAN-Phosphothreonine179 def: "Protein TLK1_HUMAN with the residue 179 substituted with Phosphothreonine" [UniProtKB:Q9UKI8] xref: UniProtKB:Q9UKI8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002220 ! TLK1_HUMAN [Term] id: CCO:B0014411 name: TLK1_HUMAN-Phosphoserine190 def: "Protein TLK1_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q9UKI8] xref: UniProtKB:Q9UKI8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002220 ! TLK1_HUMAN [Term] id: CCO:B0014412 name: TLK1_HUMAN-Phosphoserine743 def: "Protein TLK1_HUMAN with the residue 743 substituted with Phosphoserine" [UniProtKB:Q9UKI8] xref: UniProtKB:Q9UKI8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002220 ! TLK1_HUMAN [Term] id: CCO:B0014413 name: TLK2_HUMAN-Phosphoserine99 def: "Protein TLK2_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q86UE8] xref: UniProtKB:Q86UE8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001939 ! TLK2_HUMAN [Term] id: CCO:B0014414 name: TLK2_HUMAN-Phosphoserine750 def: "Protein TLK2_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:Q86UE8] comment: By similarity xref: UniProtKB:Q86UE8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001939 ! TLK2_HUMAN [Term] id: CCO:B0014415 name: TM1L1_HUMAN-Phosphoserine314 def: "Protein TM1L1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:O75674] xref: UniProtKB:O75674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006203 ! TM1L1_HUMAN [Term] id: CCO:B0014416 name: TM1L1_HUMAN-Phosphoserine323 def: "Protein TM1L1_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:O75674] xref: UniProtKB:O75674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006203 ! TM1L1_HUMAN [Term] id: CCO:B0014417 name: TM1L1_HUMAN-Phosphotyrosine460 def: "Protein TM1L1_HUMAN with the residue 460 substituted with Phosphotyrosine" [UniProtKB:O75674] comment: By similarity xref: UniProtKB:O75674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006203 ! TM1L1_HUMAN [Term] id: CCO:B0014418 name: TMF1_HUMAN-Phosphoserine72 def: "Protein TMF1_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0014419 name: TMF1_HUMAN-Phosphoserine77 def: "Protein TMF1_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0014420 name: TNFA_HUMAN-Phosphoserine2 def: "Protein TNFA_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P01375] comment: by CK1; xref: UniProtKB:P01375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001474 ! TNFA_HUMAN [Term] id: CCO:B0014421 name: TNIK_HUMAN-Phosphoserine680 def: "Protein TNIK_HUMAN with the residue 680 substituted with Phosphoserine" [UniProtKB:Q9UKE5] xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0014422 name: TNIK_HUMAN-Phosphoserine764 def: "Protein TNIK_HUMAN with the residue 764 substituted with Phosphoserine" [UniProtKB:Q9UKE5] xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0014423 name: TNIK_HUMAN-Phosphoserine769 def: "Protein TNIK_HUMAN with the residue 769 substituted with Phosphoserine" [UniProtKB:Q9UKE5] xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0014424 name: TNIK_HUMAN-Phosphothreonine987 def: "Protein TNIK_HUMAN with the residue 987 substituted with Phosphothreonine" [UniProtKB:Q9UKE5] comment: By similarity xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0014425 name: TOM20_HUMAN-Phosphoserine135 def: "Protein TOM20_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q15388] comment: By similarity xref: UniProtKB:Q15388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006116 ! TOM20_HUMAN [Term] id: CCO:B0014426 name: TOM20_HUMAN-Phosphoserine138 def: "Protein TOM20_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q15388] xref: UniProtKB:Q15388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006116 ! TOM20_HUMAN [Term] id: CCO:B0014427 name: TOP2A_HUMAN-Phosphoserine4 def: "Protein TOP2A_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014428 name: TOP2A_HUMAN-Phosphoserine29 def: "Protein TOP2A_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014429 name: TOP2A_HUMAN-Phosphoserine1106 def: "Protein TOP2A_HUMAN with the residue 1106 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014430 name: TOP2A_HUMAN-Phosphoserine1213 def: "Protein TOP2A_HUMAN with the residue 1213 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014431 name: TOP2A_HUMAN-Phosphoserine1247 def: "Protein TOP2A_HUMAN with the residue 1247 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014432 name: TOP2A_HUMAN-Phosphoserine1295 def: "Protein TOP2A_HUMAN with the residue 1295 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014433 name: TOP2A_HUMAN-Phosphoserine1297 def: "Protein TOP2A_HUMAN with the residue 1297 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014434 name: TOP2A_HUMAN-Phosphoserine1332 def: "Protein TOP2A_HUMAN with the residue 1332 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014435 name: TOP2A_HUMAN-Phosphoserine1337 def: "Protein TOP2A_HUMAN with the residue 1337 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014436 name: TOP2A_HUMAN-Phosphothreonine1343 def: "Protein TOP2A_HUMAN with the residue 1343 substituted with Phosphothreonine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014437 name: TOP2A_HUMAN-Phosphoserine1351 def: "Protein TOP2A_HUMAN with the residue 1351 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014438 name: TOP2A_HUMAN-Phosphoserine1354 def: "Protein TOP2A_HUMAN with the residue 1354 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014439 name: TOP2A_HUMAN-Phosphoserine1374 def: "Protein TOP2A_HUMAN with the residue 1374 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014440 name: TOP2A_HUMAN-Phosphoserine1377 def: "Protein TOP2A_HUMAN with the residue 1377 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014441 name: TOP2A_HUMAN-Phosphoserine1387 def: "Protein TOP2A_HUMAN with the residue 1387 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014442 name: TOP2A_HUMAN-Phosphoserine1393 def: "Protein TOP2A_HUMAN with the residue 1393 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014443 name: TOP2A_HUMAN-Phosphoserine1469 def: "Protein TOP2A_HUMAN with the residue 1469 substituted with Phosphoserine" [UniProtKB:P11388] comment: by CK2; xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014444 name: TOP2A_HUMAN-Phosphothreonine1470 def: "Protein TOP2A_HUMAN with the residue 1470 substituted with Phosphothreonine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014445 name: TOP2A_HUMAN-Phosphoserine1471 def: "Protein TOP2A_HUMAN with the residue 1471 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014446 name: TOP2A_HUMAN-Phosphoserine1474 def: "Protein TOP2A_HUMAN with the residue 1474 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014447 name: TOP2A_HUMAN-Phosphoserine1525 def: "Protein TOP2A_HUMAN with the residue 1525 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0014448 name: TOPK_HUMAN-Phosphoserine59 def: "Protein TOPK_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:Q96KB5] xref: UniProtKB:Q96KB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002045 ! TOPK_HUMAN [Term] id: CCO:B0014449 name: TOPK_HUMAN-Phosphothreonine200 def: "Protein TOPK_HUMAN with the residue 200 substituted with Phosphothreonine" [UniProtKB:Q96KB5] comment: By similarity xref: UniProtKB:Q96KB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0002045 ! TOPK_HUMAN [Term] id: CCO:B0014450 name: TP53B_HUMAN-Phosphoserine105 def: "Protein TP53B_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014451 name: TP53B_HUMAN-Phosphoserine294 def: "Protein TP53B_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014452 name: TP53B_HUMAN-Phosphothreonine302 def: "Protein TP53B_HUMAN with the residue 302 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014453 name: TP53B_HUMAN-Phosphoserine316 def: "Protein TP53B_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014454 name: TP53B_HUMAN-Phosphoserine380 def: "Protein TP53B_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014455 name: TP53B_HUMAN-Phosphoserine500 def: "Protein TP53B_HUMAN with the residue 500 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014456 name: TP53B_HUMAN-Phosphoserine523 def: "Protein TP53B_HUMAN with the residue 523 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014457 name: TP53B_HUMAN-Phosphoserine525 def: "Protein TP53B_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014458 name: TP53B_HUMAN-Phosphothreonine543 def: "Protein TP53B_HUMAN with the residue 543 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014459 name: TP53B_HUMAN-Phosphothreonine548 def: "Protein TP53B_HUMAN with the residue 548 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014460 name: TP53B_HUMAN-Phosphoserine552 def: "Protein TP53B_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014461 name: TP53B_HUMAN-Phosphoserine566 def: "Protein TP53B_HUMAN with the residue 566 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014462 name: TP53B_HUMAN-Phosphoserine580 def: "Protein TP53B_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014463 name: TP53B_HUMAN-Phosphoserine625 def: "Protein TP53B_HUMAN with the residue 625 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014464 name: TP53B_HUMAN-Phosphoserine635 def: "Protein TP53B_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014465 name: TP53B_HUMAN-Phosphoserine639 def: "Protein TP53B_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014466 name: TP53B_HUMAN-Phosphoserine640 def: "Protein TP53B_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014467 name: TP53B_HUMAN-Phosphoserine659 def: "Protein TP53B_HUMAN with the residue 659 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014468 name: TP53B_HUMAN-Phosphoserine660 def: "Protein TP53B_HUMAN with the residue 660 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014469 name: TP53B_HUMAN-Phosphoserine662 def: "Protein TP53B_HUMAN with the residue 662 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014470 name: TP53B_HUMAN-Phosphothreonine750 def: "Protein TP53B_HUMAN with the residue 750 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014471 name: TP53B_HUMAN-Phosphoserine751 def: "Protein TP53B_HUMAN with the residue 751 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014472 name: TP53B_HUMAN-Phosphoserine754 def: "Protein TP53B_HUMAN with the residue 754 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014473 name: TP53B_HUMAN-Phosphoserine755 def: "Protein TP53B_HUMAN with the residue 755 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014474 name: TP53B_HUMAN-Phosphoserine771 def: "Protein TP53B_HUMAN with the residue 771 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014475 name: TP53B_HUMAN-Phosphoserine782 def: "Protein TP53B_HUMAN with the residue 782 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014476 name: TP53B_HUMAN-Phosphoserine784 def: "Protein TP53B_HUMAN with the residue 784 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014477 name: TP53B_HUMAN-Phosphoserine831 def: "Protein TP53B_HUMAN with the residue 831 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014478 name: TP53B_HUMAN-Phosphothreonine855 def: "Protein TP53B_HUMAN with the residue 855 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014479 name: TP53B_HUMAN-Phosphoserine892 def: "Protein TP53B_HUMAN with the residue 892 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014480 name: TP53B_HUMAN-Phosphoserine993 def: "Protein TP53B_HUMAN with the residue 993 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014481 name: TP53B_HUMAN-Phosphothreonine996 def: "Protein TP53B_HUMAN with the residue 996 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014482 name: TP53B_HUMAN-Phosphoserine999 def: "Protein TP53B_HUMAN with the residue 999 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014483 name: TP53B_HUMAN-Phosphoserine1002 def: "Protein TP53B_HUMAN with the residue 1002 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014484 name: TP53B_HUMAN-Phosphoserine1028 def: "Protein TP53B_HUMAN with the residue 1028 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014485 name: TP53B_HUMAN-Phosphothreonine1056 def: "Protein TP53B_HUMAN with the residue 1056 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014486 name: TP53B_HUMAN-Phosphoserine1068 def: "Protein TP53B_HUMAN with the residue 1068 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014487 name: TP53B_HUMAN-Phosphoserine1094 def: "Protein TP53B_HUMAN with the residue 1094 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014488 name: TP53B_HUMAN-Phosphoserine1104 def: "Protein TP53B_HUMAN with the residue 1104 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014489 name: TP53B_HUMAN-Phosphoserine1114 def: "Protein TP53B_HUMAN with the residue 1114 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014490 name: TP53B_HUMAN-Phosphothreonine1171 def: "Protein TP53B_HUMAN with the residue 1171 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014491 name: TP53B_HUMAN-Phosphothreonine1214 def: "Protein TP53B_HUMAN with the residue 1214 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014492 name: TP53B_HUMAN-Phosphoserine1216 def: "Protein TP53B_HUMAN with the residue 1216 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014493 name: TP53B_HUMAN-Phosphoserine1219 def: "Protein TP53B_HUMAN with the residue 1219 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014494 name: TP53B_HUMAN-Phosphoserine1290 def: "Protein TP53B_HUMAN with the residue 1290 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014495 name: TP53B_HUMAN-Phosphoserine1316 def: "Protein TP53B_HUMAN with the residue 1316 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014496 name: TP53B_HUMAN-Phosphoserine1317 def: "Protein TP53B_HUMAN with the residue 1317 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014497 name: TP53B_HUMAN-Phosphoserine1320 def: "Protein TP53B_HUMAN with the residue 1320 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014498 name: TP53B_HUMAN-Phosphoserine1362 def: "Protein TP53B_HUMAN with the residue 1362 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014499 name: TP53B_HUMAN-Phosphoserine1426 def: "Protein TP53B_HUMAN with the residue 1426 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014500 name: TP53B_HUMAN-Phosphoserine1430 def: "Protein TP53B_HUMAN with the residue 1430 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014501 name: TP53B_HUMAN-Phosphoserine1631 def: "Protein TP53B_HUMAN with the residue 1631 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014502 name: TP53B_HUMAN-Phosphoserine1634 def: "Protein TP53B_HUMAN with the residue 1634 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014503 name: TP53B_HUMAN-Phosphoserine1635 def: "Protein TP53B_HUMAN with the residue 1635 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014504 name: TP53B_HUMAN-Phosphothreonine1638 def: "Protein TP53B_HUMAN with the residue 1638 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014505 name: TP53B_HUMAN-Phosphothreonine1647 def: "Protein TP53B_HUMAN with the residue 1647 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000265 ! replication fork relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014506 name: TP53B_HUMAN-Phosphoserine1673 def: "Protein TP53B_HUMAN with the residue 1673 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014507 name: TP53B_HUMAN-Phosphoserine1678 def: "Protein TP53B_HUMAN with the residue 1678 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014508 name: TP53B_HUMAN-Phosphoserine1701 def: "Protein TP53B_HUMAN with the residue 1701 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014509 name: TP53B_HUMAN-Phosphoserine1705 def: "Protein TP53B_HUMAN with the residue 1705 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0014513 name: TPX2_HUMAN-Phosphothreonine51 def: "Protein TPX2_HUMAN with the residue 51 substituted with Phosphothreonine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014514 name: TPX2_HUMAN-Phosphothreonine72 def: "Protein TPX2_HUMAN with the residue 72 substituted with Phosphothreonine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014515 name: TPX2_HUMAN-Phosphoserine121 def: "Protein TPX2_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014516 name: TPX2_HUMAN-Phosphoserine125 def: "Protein TPX2_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014517 name: TPX2_HUMAN-Phosphothreonine147 def: "Protein TPX2_HUMAN with the residue 147 substituted with Phosphothreonine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014518 name: TPX2_HUMAN-Phosphoserine186 def: "Protein TPX2_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014519 name: TPX2_HUMAN-Phosphoserine293 def: "Protein TPX2_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014520 name: TPX2_HUMAN-Phosphothreonine338 def: "Protein TPX2_HUMAN with the residue 338 substituted with Phosphothreonine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014521 name: TPX2_HUMAN-Phosphoserine359 def: "Protein TPX2_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014522 name: TPX2_HUMAN-Phosphothreonine369 def: "Protein TPX2_HUMAN with the residue 369 substituted with Phosphothreonine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014523 name: TPX2_HUMAN-Phosphothreonine374 def: "Protein TPX2_HUMAN with the residue 374 substituted with Phosphothreonine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014524 name: TPX2_HUMAN-Phosphoserine486 def: "Protein TPX2_HUMAN with the residue 486 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014525 name: TPX2_HUMAN-Phosphoserine542 def: "Protein TPX2_HUMAN with the residue 542 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014526 name: TPX2_HUMAN-Phosphoserine634 def: "Protein TPX2_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014527 name: TPX2_HUMAN-Phosphoserine652 def: "Protein TPX2_HUMAN with the residue 652 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014528 name: TPX2_HUMAN-Phosphoserine654 def: "Protein TPX2_HUMAN with the residue 654 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014529 name: TPX2_HUMAN-Phosphoserine738 def: "Protein TPX2_HUMAN with the residue 738 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0014530 name: TRBM_HUMAN-3-hydroxyasparagine342 def: "Protein TRBM_HUMAN with the residue 342 substituted with 3-hydroxyasparagine" [UniProtKB:P07204] xref: UniProtKB:P07204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005618 ! TRBM_HUMAN [Term] id: CCO:B0014531 name: TRI29_HUMAN-Phosphoserine58 def: "Protein TRI29_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:Q14134] xref: UniProtKB:Q14134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:B0014532 name: TRI29_HUMAN-Phosphoserine104 def: "Protein TRI29_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:Q14134] xref: UniProtKB:Q14134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:B0014533 name: TRI29_HUMAN-Phosphoserine489 def: "Protein TRI29_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q14134] xref: UniProtKB:Q14134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:B0014534 name: TRI37_HUMAN-Phosphoserine771 def: "Protein TRI37_HUMAN with the residue 771 substituted with Phosphoserine" [UniProtKB:O94972] xref: UniProtKB:O94972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000359 ! peroxisome relationship: transformation_of CCO:B0005249 ! TRI37_HUMAN [Term] id: CCO:B0014535 name: TRI37_HUMAN-Phosphoserine773 def: "Protein TRI37_HUMAN with the residue 773 substituted with Phosphoserine" [UniProtKB:O94972] xref: UniProtKB:O94972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005249 ! TRI37_HUMAN [Term] id: CCO:B0014536 name: TRIP6_HUMAN-Phosphoserine92 def: "Protein TRIP6_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q15654] xref: UniProtKB:Q15654 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:B0014537 name: TRP13_HUMAN-Phosphotyrosine56 def: "Protein TRP13_HUMAN with the residue 56 substituted with Phosphotyrosine" [UniProtKB:Q15645] xref: UniProtKB:Q15645 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006283 ! TRP13_HUMAN [Term] id: CCO:B0014538 name: TRRAP_HUMAN-Phosphoserine2051 def: "Protein TRRAP_HUMAN with the residue 2051 substituted with Phosphoserine" [UniProtKB:Q9Y4A5] xref: UniProtKB:Q9Y4A5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:B0014539 name: TRRAP_HUMAN-Phosphoserine2077 def: "Protein TRRAP_HUMAN with the residue 2077 substituted with Phosphoserine" [UniProtKB:Q9Y4A5] xref: UniProtKB:Q9Y4A5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:B0014540 name: TSC1_HUMAN-Phosphoserine505 def: "Protein TSC1_HUMAN with the residue 505 substituted with Phosphoserine" [UniProtKB:Q92574] xref: UniProtKB:Q92574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001584 ! TSC1-TSC2 complex relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0002014 ! TSC1_HUMAN [Term] id: CCO:B0014541 name: TSC1_HUMAN-Phosphoserine1102 def: "Protein TSC1_HUMAN with the residue 1102 substituted with Phosphoserine" [UniProtKB:Q92574] xref: UniProtKB:Q92574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002014 ! TSC1_HUMAN [Term] id: CCO:B0014542 name: TSC2_HUMAN-Phosphoserine981 def: "Protein TSC2_HUMAN with the residue 981 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0014543 name: TSC2_HUMAN-Phosphoserine1364 def: "Protein TSC2_HUMAN with the residue 1364 substituted with Phosphoserine" [UniProtKB:P49815] comment: By similarity xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0014544 name: TSC2_HUMAN-Phosphoserine1387 def: "Protein TSC2_HUMAN with the residue 1387 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0014545 name: TSC2_HUMAN-Phosphoserine1411 def: "Protein TSC2_HUMAN with the residue 1411 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0014546 name: TSC2_HUMAN-Phosphoserine1418 def: "Protein TSC2_HUMAN with the residue 1418 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0014547 name: TSC2_HUMAN-Phosphoserine1420 def: "Protein TSC2_HUMAN with the residue 1420 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0014548 name: TSC2_HUMAN-Phosphoserine1798 def: "Protein TSC2_HUMAN with the residue 1798 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0014549 name: TSYL2_HUMAN-Phosphoserine16 def: "Protein TSYL2_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q9H2G4] xref: UniProtKB:Q9H2G4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000036 ! rDNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002128 ! TSYL2_HUMAN [Term] id: CCO:B0014550 name: TSYL2_HUMAN-Phosphoserine17 def: "Protein TSYL2_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q9H2G4] xref: UniProtKB:Q9H2G4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002128 ! TSYL2_HUMAN [Term] id: CCO:B0014551 name: TSYL2_HUMAN-Phosphoserine20 def: "Protein TSYL2_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q9H2G4] xref: UniProtKB:Q9H2G4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002128 ! TSYL2_HUMAN [Term] id: CCO:B0014552 name: TSYL2_HUMAN-Phosphothreonine340 def: "Protein TSYL2_HUMAN with the residue 340 substituted with Phosphothreonine" [UniProtKB:Q9H2G4] comment: Probable xref: UniProtKB:Q9H2G4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002128 ! TSYL2_HUMAN [Term] id: CCO:B0014553 name: TTK_HUMAN-Phosphoserine821 def: "Protein TTK_HUMAN with the residue 821 substituted with Phosphoserine" [UniProtKB:P33981] xref: UniProtKB:P33981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001587 ! TTK_HUMAN [Term] id: CCO:B0014554 name: TTK_HUMAN-Phosphoserine824 def: "Protein TTK_HUMAN with the residue 824 substituted with Phosphoserine" [UniProtKB:P33981] xref: UniProtKB:P33981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000388 ! spindle relationship: transformation_of CCO:B0001587 ! TTK_HUMAN [Term] id: CCO:B0014555 name: TTLL5_HUMAN-Phosphothreonine515 def: "Protein TTLL5_HUMAN with the residue 515 substituted with Phosphothreonine" [UniProtKB:Q6EMB2] xref: UniProtKB:Q6EMB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006333 ! TTLL5_HUMAN [Term] id: CCO:B0014556 name: TUSC2_HUMAN-Phosphoserine50 def: "Protein TUSC2_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:O75896] comment: By similarity xref: UniProtKB:O75896 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001438 ! TUSC2_HUMAN [Term] id: CCO:B0014557 name: TYB4_HUMAN-N-acetylserine2 def: "Protein TYB4_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62328] xref: UniProtKB:P62328 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006115 ! TYB4_HUMAN [Term] id: CCO:B0014558 name: TYB4_HUMAN-Phosphothreonine23 def: "Protein TYB4_HUMAN with the residue 23 substituted with Phosphothreonine" [UniProtKB:P62328] comment: By similarity xref: UniProtKB:P62328 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0006115 ! TYB4_HUMAN [Term] id: CCO:B0014559 name: TYY1_HUMAN-Phosphoserine118 def: "Protein TYY1_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:P25490] xref: UniProtKB:P25490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006011 ! TYY1_HUMAN [Term] id: CCO:B0014560 name: TYY1_HUMAN-Phosphoserine184 def: "Protein TYY1_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:P25490] xref: UniProtKB:P25490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0001285 ! PcG protein complex relationship: transformation_of CCO:B0006011 ! TYY1_HUMAN [Term] id: CCO:B0014561 name: TYY1_HUMAN-Phosphoserine247 def: "Protein TYY1_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:P25490] xref: UniProtKB:P25490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006011 ! TYY1_HUMAN [Term] id: CCO:B0014562 name: TYY1_HUMAN-Phosphothreonine348 def: "Protein TYY1_HUMAN with the residue 348 substituted with Phosphothreonine" [UniProtKB:P25490] xref: UniProtKB:P25490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006011 ! TYY1_HUMAN [Term] id: CCO:B0014563 name: UB2R1_HUMAN-Phosphoserine231 def: "Protein UB2R1_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:P49427] comment: by CK2; Probable xref: UniProtKB:P49427 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001628 ! UB2R1_HUMAN [Term] id: CCO:B0014564 name: UBE3A_HUMAN-Phosphoserine218 def: "Protein UBE3A_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q05086] xref: UniProtKB:Q05086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0005334 ! UBE3A_HUMAN [Term] id: CCO:B0014565 name: UBIQ_HUMAN-Phosphoserine57 def: "Protein UBIQ_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:P62988] comment: By similarity xref: UniProtKB:P62988 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001695 ! UBIQ_HUMAN [Term] id: CCO:B0014566 name: UBIQ_HUMAN-Phosphoserine65 def: "Protein UBIQ_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:P62988] xref: UniProtKB:P62988 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001695 ! UBIQ_HUMAN [Term] id: CCO:B0014567 name: UBP16_HUMAN-Phosphoserine552 def: "Protein UBP16_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:Q9Y5T5] xref: UniProtKB:Q9Y5T5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002259 ! UBP16_HUMAN [Term] id: CCO:B0014568 name: UBP5_HUMAN-Phosphothreonine623 def: "Protein UBP5_HUMAN with the residue 623 substituted with Phosphothreonine" [UniProtKB:P45974] xref: UniProtKB:P45974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005310 ! UBP5_HUMAN [Term] id: CCO:B0014569 name: UBP5_HUMAN-Phosphoserine783 def: "Protein UBP5_HUMAN with the residue 783 substituted with Phosphoserine" [UniProtKB:P45974] xref: UniProtKB:P45974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002003 ! ubiquitin-specific protease 5 activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: transformation_of CCO:B0005310 ! UBP5_HUMAN [Term] id: CCO:B0014570 name: UBP7_HUMAN-Phosphoserine18 def: "Protein UBP7_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q93009] xref: UniProtKB:Q93009 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:B0014571 name: UBQL4_HUMAN-Phosphoserine318 def: "Protein UBQL4_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q9NRR5] xref: UniProtKB:Q9NRR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:B0014572 name: UBR1_HUMAN-Phosphothreonine21 def: "Protein UBR1_HUMAN with the residue 21 substituted with Phosphothreonine" [UniProtKB:Q8IWV7] xref: UniProtKB:Q8IWV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:B0014573 name: UBR1_HUMAN-Phosphoserine1179 def: "Protein UBR1_HUMAN with the residue 1179 substituted with Phosphoserine" [UniProtKB:Q8IWV7] xref: UniProtKB:Q8IWV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:B0014576 name: UFO_HUMAN-Phosphotyrosine696 def: "Protein UFO_HUMAN with the residue 696 substituted with Phosphotyrosine" [UniProtKB:P30530] comment: by autocatalysis; By similarity xref: UniProtKB:P30530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0001579 ! UFO_HUMAN [Term] id: CCO:B0014577 name: UHRF1_HUMAN-Phosphoserine287 def: "Protein UHRF1_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q96T88] xref: UniProtKB:Q96T88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002063 ! UHRF1_HUMAN [Term] id: CCO:B0014578 name: UHRF1_HUMAN-Phosphoserine298 def: "Protein UHRF1_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:Q96T88] comment: by PKA; in vitro; xref: UniProtKB:Q96T88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002063 ! UHRF1_HUMAN [Term] id: CCO:B0014579 name: UHRF1_HUMAN-Phosphoserine639 def: "Protein UHRF1_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:Q96T88] xref: UniProtKB:Q96T88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002063 ! UHRF1_HUMAN [Term] id: CCO:B0014581 name: UN84B_HUMAN-Phosphoserine12 def: "Protein UN84B_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q9UH99] xref: UniProtKB:Q9UH99 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002199 ! UN84B_HUMAN [Term] id: CCO:B0014582 name: UN84B_HUMAN-Phosphoserine38 def: "Protein UN84B_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:Q9UH99] comment: By similarity xref: UniProtKB:Q9UH99 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000111 ! nuclear chromosome, telomeric region relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0002199 ! UN84B_HUMAN [Term] id: CCO:B0014583 name: UN84B_HUMAN-Phosphoserine54 def: "Protein UN84B_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q9UH99] xref: UniProtKB:Q9UH99 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002199 ! UN84B_HUMAN [Term] id: CCO:B0014584 name: UN84B_HUMAN-Phosphoserine116 def: "Protein UN84B_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q9UH99] xref: UniProtKB:Q9UH99 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002199 ! UN84B_HUMAN [Term] id: CCO:B0014585 name: UT14A_HUMAN-Phosphoserine29 def: "Protein UT14A_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0014586 name: UT14A_HUMAN-Phosphoserine31 def: "Protein UT14A_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0014587 name: UT14A_HUMAN-Phosphoserine434 def: "Protein UT14A_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0014588 name: UT14A_HUMAN-Phosphoserine437 def: "Protein UT14A_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0014589 name: UT14A_HUMAN-Phosphoserine445 def: "Protein UT14A_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002175 ! small-subunit processome relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0014590 name: UT14A_HUMAN-Phosphoserine451 def: "Protein UT14A_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0014591 name: UT14A_HUMAN-Phosphoserine453 def: "Protein UT14A_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0014592 name: VDAC1_HUMAN-N-acetylalanine2 def: "Protein VDAC1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P21796] xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014593 name: VDAC1_HUMAN-Phosphoserine13 def: "Protein VDAC1_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P21796] comment: By similarity xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001822 ! voltage-gated anion channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: located_in CCO:C0001978 ! pore complex relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014594 name: VDAC1_HUMAN-N6-acetyllysine20 def: "Protein VDAC1_HUMAN with the residue 20 substituted with N6-acetyllysine" [UniProtKB:P21796] comment: By similarity xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014595 name: VDAC1_HUMAN-N6-acetyllysine28 def: "Protein VDAC1_HUMAN with the residue 28 substituted with N6-acetyllysine" [UniProtKB:P21796] comment: By similarity xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014596 name: VDAC1_HUMAN-N6-acetyllysine61 def: "Protein VDAC1_HUMAN with the residue 61 substituted with N6-acetyllysine" [UniProtKB:P21796] comment: By similarity xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014597 name: VDAC1_HUMAN-Phosphoserine104 def: "Protein VDAC1_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:P21796] xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014598 name: VDAC1_HUMAN-Phosphoserine137 def: "Protein VDAC1_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:P21796] comment: By similarity xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014599 name: VDAC1_HUMAN-Phosphotyrosine195 def: "Protein VDAC1_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:P21796] xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014600 name: VDAC1_HUMAN-N6-acetyllysine224 def: "Protein VDAC1_HUMAN with the residue 224 substituted with N6-acetyllysine" [UniProtKB:P21796] comment: By similarity xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0014601 name: VDAC2_HUMAN-N6-acetyllysine31 def: "Protein VDAC2_HUMAN with the residue 31 substituted with N6-acetyllysine" [UniProtKB:P45880] comment: By similarity xref: UniProtKB:P45880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005777 ! VDAC2_HUMAN [Term] id: CCO:B0014602 name: VDAC2_HUMAN-N6-acetyllysine74 def: "Protein VDAC2_HUMAN with the residue 74 substituted with N6-acetyllysine" [UniProtKB:P45880] comment: By similarity xref: UniProtKB:P45880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005777 ! VDAC2_HUMAN [Term] id: CCO:B0014603 name: VDAC2_HUMAN-Phosphoserine115 def: "Protein VDAC2_HUMAN with the residue 115 substituted with Phosphoserine" [UniProtKB:P45880] xref: UniProtKB:P45880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001822 ! voltage-gated anion channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: transformation_of CCO:B0005777 ! VDAC2_HUMAN [Term] id: CCO:B0014604 name: VDAC2_HUMAN-Phosphotyrosine236 def: "Protein VDAC2_HUMAN with the residue 236 substituted with Phosphotyrosine" [UniProtKB:P45880] comment: By similarity xref: UniProtKB:P45880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005777 ! VDAC2_HUMAN [Term] id: CCO:B0014605 name: VDAC3_HUMAN-N6-acetyllysine20 def: "Protein VDAC3_HUMAN with the residue 20 substituted with N6-acetyllysine" [UniProtKB:Q9Y277] comment: By similarity xref: UniProtKB:Q9Y277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005738 ! VDAC3_HUMAN [Term] id: CCO:B0014606 name: VDAC3_HUMAN-Phosphothreonine33 def: "Protein VDAC3_HUMAN with the residue 33 substituted with Phosphothreonine" [UniProtKB:Q9Y277] comment: By similarity xref: UniProtKB:Q9Y277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005738 ! VDAC3_HUMAN [Term] id: CCO:B0014607 name: VDAC3_HUMAN-N6-acetyllysine61 def: "Protein VDAC3_HUMAN with the residue 61 substituted with N6-acetyllysine" [UniProtKB:Q9Y277] comment: By similarity xref: UniProtKB:Q9Y277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001822 ! voltage-gated anion channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: transformation_of CCO:B0005738 ! VDAC3_HUMAN [Term] id: CCO:B0014608 name: VDAC3_HUMAN-Phosphotyrosine195 def: "Protein VDAC3_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:Q9Y277] xref: UniProtKB:Q9Y277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005738 ! VDAC3_HUMAN [Term] id: CCO:B0014609 name: VDAC3_HUMAN-Phosphoserine241 def: "Protein VDAC3_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:Q9Y277] comment: By similarity xref: UniProtKB:Q9Y277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005738 ! VDAC3_HUMAN [Term] id: CCO:B0014610 name: VEGFA_HUMAN-N6-acetyllysine147 def: "Protein VEGFA_HUMAN with the residue 147 substituted with N6-acetyllysine" [UniProtKB:P15692] xref: UniProtKB:P15692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001525 ! VEGFA_HUMAN [Term] id: CCO:B0014611 name: VEGFA_HUMAN-N6-acetyllysine149 def: "Protein VEGFA_HUMAN with the residue 149 substituted with N6-acetyllysine" [UniProtKB:P15692] xref: UniProtKB:P15692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001525 ! VEGFA_HUMAN [Term] id: CCO:B0014612 name: VEGFA_HUMAN-N6-acetyllysine152 def: "Protein VEGFA_HUMAN with the residue 152 substituted with N6-acetyllysine" [UniProtKB:P15692] xref: UniProtKB:P15692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001473 ! vascular endothelial growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005862 ! cell surface binding relationship: has_function CCO:F0008024 ! extracellular matrix binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: transformation_of CCO:B0001525 ! VEGFA_HUMAN [Term] id: CCO:B0014613 name: VGFR1_HUMAN-Phosphotyrosine1053 def: "Protein VGFR1_HUMAN with the residue 1053 substituted with Phosphotyrosine" [UniProtKB:P17948] comment: by autocatalysis; By similarity xref: UniProtKB:P17948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:B0014614 name: VGFR1_HUMAN-Phosphotyrosine1169 def: "Protein VGFR1_HUMAN with the residue 1169 substituted with Phosphotyrosine" [UniProtKB:P17948] comment: by autocatalysis; By similarity xref: UniProtKB:P17948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:B0014615 name: VGFR1_HUMAN-Phosphotyrosine1213 def: "Protein VGFR1_HUMAN with the residue 1213 substituted with Phosphotyrosine" [UniProtKB:P17948] comment: by autocatalysis; xref: UniProtKB:P17948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:B0014616 name: VGFR1_HUMAN-Phosphotyrosine1242 def: "Protein VGFR1_HUMAN with the residue 1242 substituted with Phosphotyrosine" [UniProtKB:P17948] comment: by autocatalysis; xref: UniProtKB:P17948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:B0014617 name: VGFR1_HUMAN-Phosphotyrosine1327 def: "Protein VGFR1_HUMAN with the residue 1327 substituted with Phosphotyrosine" [UniProtKB:P17948] comment: by autocatalysis; xref: UniProtKB:P17948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:B0014618 name: VGFR1_HUMAN-Phosphotyrosine1333 def: "Protein VGFR1_HUMAN with the residue 1333 substituted with Phosphotyrosine" [UniProtKB:P17948] comment: by autocatalysis; xref: UniProtKB:P17948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:B0014619 name: VIME_HUMAN-N-acetylserine2 def: "Protein VIME_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014620 name: VIME_HUMAN-Phosphoserine5 def: "Protein VIME_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014621 name: VIME_HUMAN-Phosphoserine7 def: "Protein VIME_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKA and PKC; xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014622 name: VIME_HUMAN-Phosphoserine8 def: "Protein VIME_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014623 name: VIME_HUMAN-Phosphoserine9 def: "Protein VIME_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKC; xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014624 name: VIME_HUMAN-Phosphoserine10 def: "Protein VIME_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKC; xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014625 name: VIME_HUMAN-Phosphoserine25 def: "Protein VIME_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKA and PKC; By similarity xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014626 name: VIME_HUMAN-Phosphoserine26 def: "Protein VIME_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKC; By similarity xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014627 name: VIME_HUMAN-Phosphoserine27 def: "Protein VIME_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014628 name: VIME_HUMAN-Phosphoserine34 def: "Protein VIME_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKC; By similarity xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014629 name: VIME_HUMAN-Phosphoserine39 def: "Protein VIME_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:P08670] comment: by CaMK2, PKA and PKC; xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014630 name: VIME_HUMAN-Phosphoserine42 def: "Protein VIME_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKC; xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014631 name: VIME_HUMAN-Phosphoserine47 def: "Protein VIME_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014632 name: VIME_HUMAN-Phosphoserine51 def: "Protein VIME_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKA and PKC; By similarity xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014633 name: VIME_HUMAN-Phosphoserine55 def: "Protein VIME_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014634 name: VIME_HUMAN-Phosphoserine56 def: "Protein VIME_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014635 name: VIME_HUMAN-Phosphotyrosine61 def: "Protein VIME_HUMAN with the residue 61 substituted with Phosphotyrosine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014636 name: VIME_HUMAN-Phosphoserine66 def: "Protein VIME_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:P08670] comment: by PKA and PKC; By similarity xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014637 name: VIME_HUMAN-Phosphoserine72 def: "Protein VIME_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014638 name: VIME_HUMAN-Phosphoserine73 def: "Protein VIME_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014639 name: VIME_HUMAN-Phosphoserine83 def: "Protein VIME_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P08670] comment: by CaMK2; By similarity xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014640 name: VIME_HUMAN-Phosphotyrosine117 def: "Protein VIME_HUMAN with the residue 117 substituted with Phosphotyrosine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014641 name: VIME_HUMAN-Phosphoserine214 def: "Protein VIME_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014642 name: VIME_HUMAN-Phosphoserine412 def: "Protein VIME_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014643 name: VIME_HUMAN-Phosphoserine420 def: "Protein VIME_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014644 name: VIME_HUMAN-Phosphoserine430 def: "Protein VIME_HUMAN with the residue 430 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014645 name: VIME_HUMAN-Phosphothreonine446 def: "Protein VIME_HUMAN with the residue 446 substituted with Phosphothreonine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014646 name: VIME_HUMAN-Phosphothreonine458 def: "Protein VIME_HUMAN with the residue 458 substituted with Phosphothreonine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014647 name: VIME_HUMAN-Phosphoserine459 def: "Protein VIME_HUMAN with the residue 459 substituted with Phosphoserine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0014648 name: VPS72_HUMAN-Phosphothreonine168 def: "Protein VPS72_HUMAN with the residue 168 substituted with Phosphothreonine" [UniProtKB:Q15906] xref: UniProtKB:Q15906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005361 ! VPS72_HUMAN [Term] id: CCO:B0014649 name: WAPL_HUMAN-Phosphoserine77 def: "Protein WAPL_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0014650 name: WAPL_HUMAN-Phosphoserine221 def: "Protein WAPL_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0014651 name: WAPL_HUMAN-Phosphoserine226 def: "Protein WAPL_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0014652 name: WAPL_HUMAN-Phosphoserine459 def: "Protein WAPL_HUMAN with the residue 459 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0014653 name: WAPL_HUMAN-Phosphoserine461 def: "Protein WAPL_HUMAN with the residue 461 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0014654 name: WASL_HUMAN-Phosphotyrosine256 def: "Protein WASL_HUMAN with the residue 256 substituted with Phosphotyrosine" [UniProtKB:O00401] xref: UniProtKB:O00401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005942 ! WASL_HUMAN [Term] id: CCO:B0014655 name: WBP11_HUMAN-Phosphoserine237 def: "Protein WBP11_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014656 name: WBP11_HUMAN-Phosphoserine251 def: "Protein WBP11_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014657 name: WBP11_HUMAN-Phosphothreonine252 def: "Protein WBP11_HUMAN with the residue 252 substituted with Phosphothreonine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014658 name: WBP11_HUMAN-Phosphoserine253 def: "Protein WBP11_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014659 name: WBP11_HUMAN-Phosphoserine270 def: "Protein WBP11_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014660 name: WBP11_HUMAN-Phosphothreonine271 def: "Protein WBP11_HUMAN with the residue 271 substituted with Phosphothreonine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014661 name: WBP11_HUMAN-Phosphoserine274 def: "Protein WBP11_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014662 name: WBP11_HUMAN-Phosphothreonine276 def: "Protein WBP11_HUMAN with the residue 276 substituted with Phosphothreonine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014663 name: WBP11_HUMAN-Phosphoserine279 def: "Protein WBP11_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014664 name: WBP11_HUMAN-Phosphoserine283 def: "Protein WBP11_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014665 name: WBP11_HUMAN-Phosphoserine353 def: "Protein WBP11_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014666 name: WBP11_HUMAN-Phosphoserine361 def: "Protein WBP11_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014667 name: WBP11_HUMAN-Phosphoserine364 def: "Protein WBP11_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0014668 name: WBP2_HUMAN-Phosphotyrosine232 def: "Protein WBP2_HUMAN with the residue 232 substituted with Phosphotyrosine" [UniProtKB:Q969T9] xref: UniProtKB:Q969T9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006351 ! WBP2_HUMAN [Term] id: CCO:B0014673 name: WDR26_HUMAN-Phosphoserine121 def: "Protein WDR26_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q9H7D7] xref: UniProtKB:Q9H7D7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005689 ! WDR26_HUMAN [Term] id: CCO:B0014674 name: WDR33_HUMAN-Phosphoserine7 def: "Protein WDR33_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q9C0J8] xref: UniProtKB:Q9C0J8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:B0014675 name: WDR5_HUMAN-Phosphoserine267 def: "Protein WDR5_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:P61964] xref: UniProtKB:P61964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005615 ! WDR5_HUMAN [Term] id: CCO:B0014676 name: WDR61_HUMAN-N-acetylthreonine2 def: "Protein WDR61_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:Q9GZS3] comment: By similarity xref: UniProtKB:Q9GZS3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005999 ! WDR61_HUMAN [Term] id: CCO:B0014677 name: WDR62_HUMAN-Phosphoserine33 def: "Protein WDR62_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014678 name: WDR62_HUMAN-Phosphoserine987 def: "Protein WDR62_HUMAN with the residue 987 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014679 name: WDR62_HUMAN-Phosphoserine992 def: "Protein WDR62_HUMAN with the residue 992 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014680 name: WDR62_HUMAN-Phosphoserine995 def: "Protein WDR62_HUMAN with the residue 995 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014681 name: WDR62_HUMAN-Phosphothreonine1053 def: "Protein WDR62_HUMAN with the residue 1053 substituted with Phosphothreonine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014682 name: WDR62_HUMAN-Phosphoserine1070 def: "Protein WDR62_HUMAN with the residue 1070 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014683 name: WDR62_HUMAN-Phosphoserine1093 def: "Protein WDR62_HUMAN with the residue 1093 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014684 name: WDR62_HUMAN-Phosphoserine1101 def: "Protein WDR62_HUMAN with the residue 1101 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014685 name: WDR62_HUMAN-Phosphoserine1228 def: "Protein WDR62_HUMAN with the residue 1228 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014686 name: WDR62_HUMAN-Phosphoserine1348 def: "Protein WDR62_HUMAN with the residue 1348 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014687 name: WDR62_HUMAN-Phosphoserine1405 def: "Protein WDR62_HUMAN with the residue 1405 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0014688 name: WDR82_HUMAN-Phosphoserine154 def: "Protein WDR82_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q6UXN9] comment: By similarity xref: UniProtKB:Q6UXN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005688 ! WDR82_HUMAN [Term] id: CCO:B0014689 name: WEE1_HUMAN-Phosphoserine123 def: "Protein WEE1_HUMAN with the residue 123 substituted with Phosphoserine" [UniProtKB:P30291] comment: by CDC2; Potential xref: UniProtKB:P30291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001575 ! WEE1_HUMAN [Term] id: CCO:B0014690 name: WEE1_HUMAN-Phosphoserine127 def: "Protein WEE1_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:P30291] xref: UniProtKB:P30291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001575 ! WEE1_HUMAN [Term] id: CCO:B0014691 name: WEE1_HUMAN-Phosphoserine139 def: "Protein WEE1_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:P30291] xref: UniProtKB:P30291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001575 ! WEE1_HUMAN [Term] id: CCO:B0014692 name: WEE1_HUMAN-Phosphoserine165 def: "Protein WEE1_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:P30291] xref: UniProtKB:P30291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001575 ! WEE1_HUMAN [Term] id: CCO:B0014693 name: WEE1_HUMAN-Phosphothreonine173 def: "Protein WEE1_HUMAN with the residue 173 substituted with Phosphothreonine" [UniProtKB:P30291] xref: UniProtKB:P30291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001575 ! WEE1_HUMAN [Term] id: CCO:B0014694 name: WEE1_HUMAN-Phosphoserine642 def: "Protein WEE1_HUMAN with the residue 642 substituted with Phosphoserine" [UniProtKB:P30291] comment: by BRSK1; in vitro; xref: UniProtKB:P30291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001575 ! WEE1_HUMAN [Term] id: CCO:B0014695 name: WNK4_HUMAN-Phosphoserine331 def: "Protein WNK4_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q96J92] comment: by autocatalysis; xref: UniProtKB:Q96J92 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005934 ! WNK4_HUMAN [Term] id: CCO:B0014696 name: WNK4_HUMAN-Phosphoserine335 def: "Protein WNK4_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q96J92] comment: by autocatalysis; xref: UniProtKB:Q96J92 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005934 ! WNK4_HUMAN [Term] id: CCO:B0014697 name: WRN_HUMAN-Phosphoserine1058 def: "Protein WRN_HUMAN with the residue 1058 substituted with Phosphoserine" [UniProtKB:Q14191] xref: UniProtKB:Q14191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:B0014698 name: WRN_HUMAN-Phosphoserine1141 def: "Protein WRN_HUMAN with the residue 1141 substituted with Phosphoserine" [UniProtKB:Q14191] xref: UniProtKB:Q14191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000085 ! Y-form DNA binding relationship: has_function CCO:F0000087 ! bubble DNA binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0002383 ! four-way junction helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005800 ! 3'-5' DNA helicase activity relationship: has_function CCO:F0008203 ! G-quadruplex DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0001441 ! MutLalpha complex relationship: transformation_of CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:B0014699 name: WWC1_HUMAN-Phosphoserine899 def: "Protein WWC1_HUMAN with the residue 899 substituted with Phosphoserine" [UniProtKB:Q8IX03] comment: By similarity xref: UniProtKB:Q8IX03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:B0014700 name: WWC1_HUMAN-Phosphoserine922 def: "Protein WWC1_HUMAN with the residue 922 substituted with Phosphoserine" [UniProtKB:Q8IX03] xref: UniProtKB:Q8IX03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:B0014701 name: WWC1_HUMAN-Phosphothreonine923 def: "Protein WWC1_HUMAN with the residue 923 substituted with Phosphothreonine" [UniProtKB:Q8IX03] xref: UniProtKB:Q8IX03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:B0014702 name: WWC1_HUMAN-Phosphoserine927 def: "Protein WWC1_HUMAN with the residue 927 substituted with Phosphoserine" [UniProtKB:Q8IX03] xref: UniProtKB:Q8IX03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:B0014703 name: WWOX_HUMAN-Phosphoserine14 def: "Protein WWOX_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q9NZC7] comment: By similarity xref: UniProtKB:Q9NZC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002181 ! WWOX_HUMAN [Term] id: CCO:B0014704 name: WWOX_HUMAN-Phosphotyrosine33 def: "Protein WWOX_HUMAN with the residue 33 substituted with Phosphotyrosine" [UniProtKB:Q9NZC7] xref: UniProtKB:Q9NZC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002181 ! WWOX_HUMAN [Term] id: CCO:B0014707 name: XPA_HUMAN-Phosphoserine196 def: "Protein XPA_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:P23025] xref: UniProtKB:P23025 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005345 ! XPA_HUMAN [Term] id: CCO:B0014708 name: XPC_HUMAN-Phosphoserine94 def: "Protein XPC_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0014709 name: XPC_HUMAN-Phosphoserine347 def: "Protein XPC_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0014710 name: XPC_HUMAN-Phosphoserine351 def: "Protein XPC_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0014711 name: XPC_HUMAN-Phosphoserine883 def: "Protein XPC_HUMAN with the residue 883 substituted with Phosphoserine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0014712 name: XPC_HUMAN-Phosphoserine884 def: "Protein XPC_HUMAN with the residue 884 substituted with Phosphoserine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0014713 name: XPC_HUMAN-Phosphoserine892 def: "Protein XPC_HUMAN with the residue 892 substituted with Phosphoserine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0014714 name: XPO1_HUMAN-Phosphoserine397 def: "Protein XPO1_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:O14980] xref: UniProtKB:O14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000259 ! annulate lamellae relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005867 ! XPO1_HUMAN [Term] id: CCO:B0014715 name: XPO2_HUMAN-N-acetylmethionine1 def: "Protein XPO2_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P55060] xref: UniProtKB:P55060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005662 ! XPO2_HUMAN [Term] id: CCO:B0014716 name: XPO7_HUMAN-N-acetylalanine2 def: "Protein XPO7_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9UIA9] xref: UniProtKB:Q9UIA9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005665 ! XPO7_HUMAN [Term] id: CCO:B0014717 name: XRCC2_HUMAN-Phosphoserine247 def: "Protein XRCC2_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:O43543] xref: UniProtKB:O43543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001392 ! XRCC2_HUMAN [Term] id: CCO:B0014718 name: XRCC2_HUMAN-Phosphoserine249 def: "Protein XRCC2_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:O43543] xref: UniProtKB:O43543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001392 ! XRCC2_HUMAN [Term] id: CCO:B0014719 name: XRCC4_HUMAN-Phosphoserine260 def: "Protein XRCC4_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:Q13426] comment: by PRKDC; xref: UniProtKB:Q13426 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005651 ! XRCC4_HUMAN [Term] id: CCO:B0014720 name: XRCC4_HUMAN-Phosphoserine320 def: "Protein XRCC4_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q13426] comment: by PRKDC; xref: UniProtKB:Q13426 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005651 ! XRCC4_HUMAN [Term] id: CCO:B0014721 name: XRN1_HUMAN-Phosphoserine1173 def: "Protein XRN1_HUMAN with the residue 1173 substituted with Phosphoserine" [UniProtKB:Q8IZH2] xref: UniProtKB:Q8IZH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001954 ! XRN1_HUMAN [Term] id: CCO:B0014722 name: XRN1_HUMAN-Phosphoserine1176 def: "Protein XRN1_HUMAN with the residue 1176 substituted with Phosphoserine" [UniProtKB:Q8IZH2] xref: UniProtKB:Q8IZH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001954 ! XRN1_HUMAN [Term] id: CCO:B0014723 name: YBOX1_HUMAN-Phosphoserine102 def: "Protein YBOX1_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:P67809] comment: by PKB/AKT1; xref: UniProtKB:P67809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:B0014724 name: YBOX1_HUMAN-Phosphotyrosine162 def: "Protein YBOX1_HUMAN with the residue 162 substituted with Phosphotyrosine" [UniProtKB:P67809] xref: UniProtKB:P67809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:B0014725 name: YBOX1_HUMAN-Phosphoserine165 def: "Protein YBOX1_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:P67809] xref: UniProtKB:P67809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:B0014726 name: YBOX1_HUMAN-Phosphoserine174 def: "Protein YBOX1_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:P67809] xref: UniProtKB:P67809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:B0014727 name: YBOX1_HUMAN-Phosphoserine176 def: "Protein YBOX1_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:P67809] xref: UniProtKB:P67809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:B0014728 name: YBOX1_HUMAN-Phosphoserine314 def: "Protein YBOX1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:P67809] xref: UniProtKB:P67809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:B0014729 name: YES_HUMAN-Phosphotyrosine426 def: "Protein YES_HUMAN with the residue 426 substituted with Phosphotyrosine" [UniProtKB:P07947] comment: by autocatalysis; xref: UniProtKB:P07947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005465 ! YES_HUMAN [Term] id: CCO:B0014730 name: YES_HUMAN-Phosphotyrosine537 def: "Protein YES_HUMAN with the residue 537 substituted with Phosphotyrosine" [UniProtKB:P07947] xref: UniProtKB:P07947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005465 ! YES_HUMAN [Term] id: CCO:B0014731 name: ZC11A_HUMAN-Phosphoserine108 def: "Protein ZC11A_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014732 name: ZC11A_HUMAN-Phosphoserine116 def: "Protein ZC11A_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014733 name: ZC11A_HUMAN-Phosphoserine132 def: "Protein ZC11A_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014734 name: ZC11A_HUMAN-Phosphoserine290 def: "Protein ZC11A_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014735 name: ZC11A_HUMAN-Phosphoserine495 def: "Protein ZC11A_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014736 name: ZC11A_HUMAN-Phosphoserine758 def: "Protein ZC11A_HUMAN with the residue 758 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014737 name: ZC11A_HUMAN-Phosphoserine759 def: "Protein ZC11A_HUMAN with the residue 759 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014738 name: ZC11A_HUMAN-Phosphoserine761 def: "Protein ZC11A_HUMAN with the residue 761 substituted with Phosphoserine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014739 name: ZC11A_HUMAN-Phosphothreonine762 def: "Protein ZC11A_HUMAN with the residue 762 substituted with Phosphothreonine" [UniProtKB:O75152] xref: UniProtKB:O75152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:B0014740 name: ZHX1_HUMAN-Phosphothreonine36 def: "Protein ZHX1_HUMAN with the residue 36 substituted with Phosphothreonine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0014741 name: ZHX1_HUMAN-Phosphoserine45 def: "Protein ZHX1_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0014742 name: ZHX1_HUMAN-Phosphoserine47 def: "Protein ZHX1_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0014743 name: ZHX1_HUMAN-Phosphoserine48 def: "Protein ZHX1_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0014744 name: ZHX1_HUMAN-Phosphoserine648 def: "Protein ZHX1_HUMAN with the residue 648 substituted with Phosphoserine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0014745 name: ZHX1_HUMAN-Phosphothreonine682 def: "Protein ZHX1_HUMAN with the residue 682 substituted with Phosphothreonine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0014746 name: ZNF24_HUMAN-Phosphoserine261 def: "Protein ZNF24_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:P17028] xref: UniProtKB:P17028 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:B0014747 name: ZNF24_HUMAN-Phosphotyrosine279 def: "Protein ZNF24_HUMAN with the residue 279 substituted with Phosphotyrosine" [UniProtKB:P17028] xref: UniProtKB:P17028 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:B0014748 name: ZNF24_HUMAN-Phosphotyrosine335 def: "Protein ZNF24_HUMAN with the residue 335 substituted with Phosphotyrosine" [UniProtKB:P17028] xref: UniProtKB:P17028 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:B0014749 name: ZNHI1_HUMAN-Phosphothreonine103 def: "Protein ZNHI1_HUMAN with the residue 103 substituted with Phosphothreonine" [UniProtKB:O43257] comment: by MAPK11 and MAPK14; xref: UniProtKB:O43257 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005362 ! ZNHI1_HUMAN [Term] id: CCO:B0014750 name: ZO1_HUMAN-Phosphoserine166 def: "Protein ZO1_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014751 name: ZO1_HUMAN-Phosphoserine168 def: "Protein ZO1_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014752 name: ZO1_HUMAN-Phosphoserine175 def: "Protein ZO1_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:Q07157] comment: By similarity xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014753 name: ZO1_HUMAN-Phosphoserine275 def: "Protein ZO1_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014754 name: ZO1_HUMAN-Phosphoserine277 def: "Protein ZO1_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014755 name: ZO1_HUMAN-Phosphoserine280 def: "Protein ZO1_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014756 name: ZO1_HUMAN-Phosphoserine284 def: "Protein ZO1_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q07157] comment: By similarity xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014757 name: ZO1_HUMAN-Phosphoserine297 def: "Protein ZO1_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:Q07157] comment: By similarity xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014758 name: ZO1_HUMAN-Phosphoserine300 def: "Protein ZO1_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q07157] comment: By similarity xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014759 name: ZO1_HUMAN-Phosphoserine337 def: "Protein ZO1_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000465 ! cell-cell adherens junction relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001769 ! apical junction complex relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014760 name: ZO1_HUMAN-Phosphoserine402 def: "Protein ZO1_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014761 name: ZO1_HUMAN-Phosphoserine617 def: "Protein ZO1_HUMAN with the residue 617 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014762 name: ZO1_HUMAN-Phosphothreonine868 def: "Protein ZO1_HUMAN with the residue 868 substituted with Phosphothreonine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014763 name: ZO1_HUMAN-Phosphoserine1366 def: "Protein ZO1_HUMAN with the residue 1366 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0014764 name: ZW10_HUMAN-Phosphothreonine438 def: "Protein ZW10_HUMAN with the residue 438 substituted with Phosphothreonine" [UniProtKB:O43264] xref: UniProtKB:O43264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004138 ! centromeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000396 ! kinetochore microtubule relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001387 ! ZW10_HUMAN [Term] id: CCO:B0014769 name: ZYX_HUMAN-Phosphoserine142 def: "Protein ZYX_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014770 name: ZYX_HUMAN-Phosphoserine143 def: "Protein ZYX_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014771 name: ZYX_HUMAN-Phosphothreonine159 def: "Protein ZYX_HUMAN with the residue 159 substituted with Phosphothreonine" [UniProtKB:Q15942] comment: By similarity xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014772 name: ZYX_HUMAN-Phosphothreonine179 def: "Protein ZYX_HUMAN with the residue 179 substituted with Phosphothreonine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014773 name: ZYX_HUMAN-Phosphoserine259 def: "Protein ZYX_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014774 name: ZYX_HUMAN-Phosphoserine267 def: "Protein ZYX_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014775 name: ZYX_HUMAN-Phosphoserine281 def: "Protein ZYX_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014776 name: ZYX_HUMAN-Phosphoserine290 def: "Protein ZYX_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014777 name: ZYX_HUMAN-Phosphoserine308 def: "Protein ZYX_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014778 name: ZYX_HUMAN-Phosphoserine344 def: "Protein ZYX_HUMAN with the residue 344 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0014779 name: ZZEF1_HUMAN-Phosphoserine1464 def: "Protein ZZEF1_HUMAN with the residue 1464 substituted with Phosphoserine" [UniProtKB:O43149] comment: By similarity xref: UniProtKB:O43149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001380 ! ZZEF1_HUMAN [Term] id: CCO:B0014780 name: ZZEF1_HUMAN-Phosphoserine2444 def: "Protein ZZEF1_HUMAN with the residue 2444 substituted with Phosphoserine" [UniProtKB:O43149] comment: By similarity xref: UniProtKB:O43149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001380 ! ZZEF1_HUMAN [Term] id: CCO:B0014816 name: KGP1A_HUMAN def: "cGMP-dependent protein kinase 1, alpha isozyme" [UniProtKB:Q13976] synonym: "CGK 1 alpha" EXACT [UniProtKB:Q13976] synonym: "cGKI-alpha" EXACT [UniProtKB:Q13976] synonym: "EC 2.7.11.12" EXACT [UniProtKB:Q13976] xref: EMBL:BAA08297.1 xref: EMBL:CAB07436.1 xref: UniProtKB:Q13976 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018401 ! PRKG1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001059 ! cGMP-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067296 ! KGP1A_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0067297 ! KGP1A_HUMAN-Phosphothreonine59 [Term] id: CCO:B0014822 name: KGP1B_HUMAN def: "cGMP-dependent protein kinase 1, beta isozyme" [UniProtKB:P14619] synonym: "cGK 1 beta" EXACT [UniProtKB:P14619] synonym: "cGKI-beta" EXACT [UniProtKB:P14619] synonym: "EC 2.7.11.12" EXACT [UniProtKB:P14619] xref: EMBL:AAI27091.1 xref: EMBL:CAA68810.1 xref: EMBL:CAB07437.1 xref: EMBL:CAI17115.1 xref: EMBL:CAI39626.1 xref: EMBL:CAI40743.1 xref: EMBL:CAI41305.1 xref: UniProtKB:P14619 xref: UniProtKB:Q5JSJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018401 ! PRKG1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001059 ! cGMP-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0014838 name: SPT6H_HUMAN def: "Transcription elongation factor SPT6" [UniProtKB:Q7KZ85] synonym: "hSPT6" EXACT [UniProtKB:Q7KZ85] synonym: "Tat-cotransactivator 2 protein" EXACT [UniProtKB:Q7KZ85] synonym: "Tat-CT2 protein" EXACT [UniProtKB:Q7KZ85] xref: EMBL:AAB18949.1 xref: EMBL:AAC28631.1 xref: EMBL:AAC50821.1 xref: EMBL:AAC99996.1 xref: EMBL:AAH03692.1 xref: EMBL:AAH03696.1 xref: EMBL:AAH17105.1 xref: EMBL:AAH33074.1 xref: EMBL:AAH73963.1 xref: EMBL:BAA11479.2 xref: UniProtKB:Q15737 xref: UniProtKB:Q6GMQ4 xref: UniProtKB:Q7KYW9 xref: UniProtKB:Q7KZ85 xref: UniProtKB:Q7LDK4 xref: UniProtKB:Q8N526 xref: UniProtKB:Q92775 xref: UniProtKB:Q96AH3 xref: UniProtKB:Q9BTH9 xref: UniProtKB:Q9BTI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020022 ! SUPT6H_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070804 ! SPT6H_HUMAN-Phosphoserine73 relationship: transforms_into CCO:B0070805 ! SPT6H_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0070806 ! SPT6H_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0070807 ! SPT6H_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0070808 ! SPT6H_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0070809 ! SPT6H_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0070810 ! SPT6H_HUMAN-Phosphothreonine1523 relationship: transforms_into CCO:B0070811 ! SPT6H_HUMAN-Phosphoserine1526 relationship: transforms_into CCO:B0070812 ! SPT6H_HUMAN-Phosphothreonine1532 relationship: transforms_into CCO:B0070813 ! SPT6H_HUMAN-Phosphoserine1535 relationship: transforms_into CCO:B0070814 ! SPT6H_HUMAN-Phosphothreonine1539 relationship: transforms_into CCO:B0070815 ! SPT6H_HUMAN-Phosphoserine1701 relationship: transforms_into CCO:B0070816 ! SPT6H_HUMAN-Phosphoserine1703 relationship: transforms_into CCO:B0070817 ! SPT6H_HUMAN-Phosphothreonine1718 [Term] id: CCO:B0014847 name: SETD2_HUMAN def: "Histone-lysine N-methyltransferase SETD2" [UniProtKB:Q9BYW2] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9BYW2] synonym: "HIF-1" EXACT [UniProtKB:Q9BYW2] synonym: "hSET2" EXACT [UniProtKB:Q9BYW2] synonym: "Huntingtin yeast partner B" EXACT [UniProtKB:Q9BYW2] synonym: "Huntingtin-interacting protein 1" EXACT [UniProtKB:Q9BYW2] synonym: "Huntingtin-interacting protein B" EXACT [UniProtKB:Q9BYW2] synonym: "Lysine N-methyltransferase 3A" EXACT [UniProtKB:Q9BYW2] synonym: "p231HBP" EXACT [UniProtKB:Q9BYW2] synonym: "SET domain-containing protein 2" EXACT [UniProtKB:Q9BYW2] xref: EMBL:AAC26194.1 xref: EMBL:AAC26846.1 xref: EMBL:AAF29041.1 xref: EMBL:AAH72440.1 xref: EMBL:AAH90954.1 xref: EMBL:AAI17163.1 xref: EMBL:AAI17165.1 xref: EMBL:AAT77612.1 xref: EMBL:AAT77613.1 xref: EMBL:BAB15367.1 xref: EMBL:BAB21823.2 xref: EMBL:BAC87131.1 xref: EMBL:BAD18522.1 xref: EMBL:CAC28349.1 xref: EMBL:CAD28492.1 xref: EMBL:CAD38601.2 xref: EMBL:CAH10589.1 xref: UniProtKB:O75397 xref: UniProtKB:O75405 xref: UniProtKB:Q17RW8 xref: UniProtKB:Q5BKS9 xref: UniProtKB:Q5QGN2 xref: UniProtKB:Q69YI5 xref: UniProtKB:Q6IN64 xref: UniProtKB:Q6ZN53 xref: UniProtKB:Q6ZS25 xref: UniProtKB:Q8N3R0 xref: UniProtKB:Q8TCN0 xref: UniProtKB:Q9BYW2 xref: UniProtKB:Q9C0D1 xref: UniProtKB:Q9H696 xref: UniProtKB:Q9NZW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015003 ! SETD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052728 ! SETD2_HUMAN-Phosphoserine321 relationship: transforms_into CCO:B0052729 ! SETD2_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0052730 ! SETD2_HUMAN-Phosphoserine532 relationship: transforms_into CCO:B0052731 ! SETD2_HUMAN-Phosphoserine1228 relationship: transforms_into CCO:B0052732 ! SETD2_HUMAN-Phosphoserine1413 relationship: transforms_into CCO:B0070378 ! SETD2_HUMAN-Phosphoserine624 relationship: transforms_into CCO:B0070379 ! SETD2_HUMAN-Phosphoserine742 relationship: transforms_into CCO:B0070380 ! SETD2_HUMAN-Phosphoserine754 relationship: transforms_into CCO:B0070381 ! SETD2_HUMAN-Phosphoserine1415 relationship: transforms_into CCO:B0070382 ! SETD2_HUMAN-Phosphoserine1417 relationship: transforms_into CCO:B0070383 ! SETD2_HUMAN-Phosphothreonine1872 relationship: transforms_into CCO:B0070384 ! SETD2_HUMAN-Phosphoserine2080 relationship: transforms_into CCO:B0070385 ! SETD2_HUMAN-Phosphoserine2082 [Term] id: CCO:B0014899 name: IPSP_HUMAN def: "Plasma serine protease inhibitor precursor" [UniProtKB:P05154] synonym: "Acrosomal serine protease inhibitor" EXACT [UniProtKB:P05154] synonym: "PAI-3" EXACT [UniProtKB:P05154] synonym: "PAI3" EXACT [UniProtKB:P05154] synonym: "PCI" EXACT [UniProtKB:P05154] synonym: "Plasminogen activator inhibitor 3" EXACT [UniProtKB:P05154] synonym: "Protein C inhibitor" EXACT [UniProtKB:P05154] synonym: "Serpin A5" EXACT [UniProtKB:P05154] xref: EMBL:AAA02811.1 xref: EMBL:AAA35688.1 xref: EMBL:AAB26244.2 xref: EMBL:AAB30461.1 xref: EMBL:AAB60386.1 xref: EMBL:AAH08915.1 xref: EMBL:AAK27240.1 xref: EMBL:CAB45766.1 xref: UniProtKB:P05154 xref: UniProtKB:Q07616 xref: UniProtKB:Q9UG30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007677 ! SERPINA5_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001663 ! glycosaminoglycan binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0004966 ! acrosin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0020452 ! serpina5-cops6 physical interaction relationship: participates_in CCO:P0002578 ! negative regulation of proteolysis [Term] id: CCO:B0014914 name: POLH_HUMAN def: "DNA polymerase eta" [UniProtKB:Q9Y253] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9Y253] synonym: "RAD30 homolog A" EXACT [UniProtKB:Q9Y253] synonym: "Xeroderma pigmentosum variant type protein" EXACT [UniProtKB:Q9Y253] xref: EMBL:AAD43810.1 xref: EMBL:AAH15742.1 xref: EMBL:AAQ81300.1 xref: EMBL:BAA81666.1 xref: EMBL:BAB18601.1 xref: EMBL:CAI12786.1 xref: EMBL:CAI12787.1 xref: EMBL:CAI42641.1 xref: EMBL:CAI42642.1 xref: UniProtKB:Q7L8E3 xref: UniProtKB:Q96BC4 xref: UniProtKB:Q9BX13 xref: UniProtKB:Q9Y253 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007991 ! POLH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000643 ! regulation of DNA repair relationship: transforms_into CCO:B0035405 ! POLH_HUMAN-Phosphoserine379 relationship: transforms_into CCO:B0035406 ! POLH_HUMAN-Phosphoserine380 [Term] id: CCO:B0014928 name: TAF9B_HUMAN def: "Transcription initiation factor TFIID subunit 9B" [UniProtKB:Q9HBM6] synonym: "DN-7" EXACT [UniProtKB:Q9HBM6] synonym: "Neuronal cell death-related protein 7" EXACT [UniProtKB:Q9HBM6] synonym: "Transcription initiation factor TFIID subunit 9-like" EXACT [UniProtKB:Q9HBM6] synonym: "Transcription-associated factor TAFII31L" EXACT [UniProtKB:Q9HBM6] xref: EMBL:AAD27786.1 xref: EMBL:AAG09711.1 xref: EMBL:AAH09566.1 xref: EMBL:AAH10350.1 xref: EMBL:AAH71649.1 xref: EMBL:CAI42952.1 xref: UniProtKB:Q9HBM6 xref: UniProtKB:Q9Y2S3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008262 ! TAF9B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:I0015749 ! drap1-taf9l physical interaction relationship: participates_in CCO:I0015813 ! runx1t1-taf9l physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035723 ! TAF9B_HUMAN-Phosphothreonine156 [Term] id: CCO:B0014938 name: AIFM1_HUMAN def: "Apoptosis-inducing factor 1, mitochondrial precursor" [UniProtKB:O95831] synonym: "EC 1.-.-.-" EXACT [UniProtKB:O95831] synonym: "Programmed cell death protein 8" EXACT [UniProtKB:O95831] xref: EMBL:AAD16436.1 xref: EMBL:AAD20036.1 xref: EMBL:AAI11066.1 xref: EMBL:CAB41267.1 xref: EMBL:CAB41268.1 xref: EMBL:CAG33660.1 xref: EMBL:CAI42778.1 xref: EMBL:CAI42780.1 xref: UniProtKB:O95831 xref: UniProtKB:Q5JUZ7 xref: UniProtKB:Q6I9X6 xref: UniProtKB:Q9Y3I3 xref: UniProtKB:Q9Y3I4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007226 ! AIFM1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000341 ! mitochondrial intermembrane space relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0016160 ! pdcd8-tsc22d4 physical interaction relationship: participates_in CCO:I0016590 ! map3k1-pdcd8 physical interaction relationship: participates_in CCO:I0016660 ! map3k3-pdcd8 physical interaction relationship: participates_in CCO:I0016774 ! nfkb2-pdcd8 physical interaction relationship: participates_in CCO:I0017037 ! tnfrsf1b-pdcd8 physical interaction relationship: participates_in CCO:I0017057 ! tradd-pdcd8 physical interaction relationship: participates_in CCO:I0017547 ! tsc22d4-pdcd8 physical interaction relationship: participates_in CCO:I0020100 ! pdcd8-setdb1 physical interaction relationship: participates_in CCO:I0020101 ! pdcd8-stc2 physical interaction relationship: participates_in CCO:I0020620 ! pdcd8-c4orf14 physical interaction relationship: participates_in CCO:I0020621 ! pdcd8-kibra physical interaction relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: transforms_into CCO:B0034528 ! AIFM1_HUMAN-N6-acetyllysine593 [Term] id: CCO:B0014941 name: EPHA6_HUMAN def: "Ephrin type-A receptor 6 precursor" [UniProtKB:Q9UF33] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q9UF33] synonym: "EPH homology kinase 2" EXACT [UniProtKB:Q9UF33] synonym: "Tyrosine-protein kinase receptor EHK-2" EXACT [UniProtKB:Q9UF33] xref: EMBL:CAB63775.1 xref: UniProtKB:Q9UF33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007495 ! EPHA6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034746 ! EPHA6_HUMAN-Phosphotyrosine605 relationship: transforms_into CCO:B0034747 ! EPHA6_HUMAN-Phosphotyrosine611 relationship: transforms_into CCO:B0034748 ! EPHA6_HUMAN-Phosphotyrosine830 relationship: transforms_into CCO:B0034749 ! EPHA6_HUMAN-Phosphotyrosine977 [Term] id: CCO:B0014942 name: EPHA4_HUMAN def: "Ephrin type-A receptor 4 precursor" [UniProtKB:P54764] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P54764] synonym: "Receptor protein-tyrosine kinase HEK8" EXACT [UniProtKB:P54764] synonym: "Tyrosine-protein kinase receptor SEK" EXACT [UniProtKB:P54764] synonym: "Tyrosine-protein kinase TYRO1" EXACT [UniProtKB:P54764] xref: EMBL:AAA74246.1 xref: EMBL:AAI05001.1 xref: EMBL:AAI05003.1 xref: UniProtKB:P54764 xref: UniProtKB:Q2M380 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007493 ! EPHA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034738 ! EPHA4_HUMAN-Phosphotyrosine596 relationship: transforms_into CCO:B0034739 ! EPHA4_HUMAN-Phosphotyrosine602 relationship: transforms_into CCO:B0034740 ! EPHA4_HUMAN-Phosphotyrosine779 relationship: transforms_into CCO:B0034741 ! EPHA4_HUMAN-Phosphotyrosine928 [Term] id: CCO:B0014944 name: EPHA5_HUMAN def: "Ephrin type-A receptor 5 precursor" [UniProtKB:P54756] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P54756] synonym: "EPH homology kinase 1" EXACT [UniProtKB:P54756] synonym: "Receptor protein-tyrosine kinase HEK7" EXACT [UniProtKB:P54756] synonym: "Tyrosine-protein kinase receptor EHK-1" EXACT [UniProtKB:P54756] xref: EMBL:AAA74245.1 xref: EMBL:CAA64700.1 xref: UniProtKB:P54756 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007494 ! EPHA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034742 ! EPHA5_HUMAN-Phosphotyrosine650 relationship: transforms_into CCO:B0034743 ! EPHA5_HUMAN-Phosphotyrosine656 relationship: transforms_into CCO:B0034744 ! EPHA5_HUMAN-Phosphotyrosine833 relationship: transforms_into CCO:B0034745 ! EPHA5_HUMAN-Phosphotyrosine982 [Term] id: CCO:B0014946 name: EPHAA_HUMAN def: "Ephrin type-A receptor 10 precursor" [UniProtKB:Q5JZY3] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q5JZY3] xref: EMBL:AAH67734.1 xref: EMBL:CAG77605.1 xref: EMBL:CAI43321.1 xref: UniProtKB:Q5JZY3 xref: UniProtKB:Q6NW42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007498 ! EPHA10_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0014947 name: Q6UWM0_HUMAN def: "EPA6" [UniProtKB:Q6UWM0] xref: EMBL:AAQ89098.1 xref: UniProtKB:Q6UWM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008803 ! UNQ6114_human relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0014952 name: Q6P4R6_HUMAN def: "Ephrin receptor" [UniProtKB:Q6P4R6] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q6P4R6] xref: EMBL:AAH63282.1 xref: UniProtKB:Q6P4R6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007492 ! EPHA3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0014956 name: Q96L35_HUMAN def: "Ephrin receptor" [UniProtKB:Q96L35] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q96L35] xref: EMBL:AAL14195.1 xref: EMBL:EAW76469.1 xref: UniProtKB:Q96L35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004575 ! EPHB4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0014957 name: EPHA8_HUMAN def: "Ephrin type-A receptor 8 precursor" [UniProtKB:P29322] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P29322] synonym: "EPH- and ELK-related kinase" EXACT [UniProtKB:P29322] synonym: "HEK3" EXACT [UniProtKB:P29322] synonym: "Tyrosine-protein kinase receptor EEK" EXACT [UniProtKB:P29322] xref: EMBL:BAA95983.1 xref: EMBL:CAA41980.1 xref: EMBL:CAB81612.1 xref: UniProtKB:P29322 xref: UniProtKB:Q9NUA9 xref: UniProtKB:Q9P269 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007497 ! EPHA8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034754 ! EPHA8_HUMAN-Phosphotyrosine616 relationship: transforms_into CCO:B0034755 ! EPHA8_HUMAN-Phosphotyrosine839 [Term] id: CCO:B0014960 name: Q8N3Z2_HUMAN def: "Ephrin receptor" [UniProtKB:Q8N3Z2] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q8N3Z2] xref: EMBL:AAH37166.1 xref: EMBL:CAH71943.1 xref: EMBL:EAW51769.1 xref: UniProtKB:Q8N3Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004573 ! EPHA2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0014961 name: EPHA7_HUMAN def: "Ephrin type-A receptor 7 precursor" [UniProtKB:Q15375] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q15375] synonym: "EPH homology kinase 3" EXACT [UniProtKB:Q15375] synonym: "Receptor protein-tyrosine kinase HEK11" EXACT [UniProtKB:Q15375] synonym: "Tyrosine-protein kinase receptor EHK-3" EXACT [UniProtKB:Q15375] xref: EMBL:AAA74243.1 xref: EMBL:AAH27940.1 xref: EMBL:AAI26126.1 xref: EMBL:AAI26152.1 xref: EMBL:BAD92506.1 xref: EMBL:CAC19520.2 xref: EMBL:CAH72780.1 xref: EMBL:CAH73650.1 xref: EMBL:CAI19722.1 xref: UniProtKB:A0AUX7 xref: UniProtKB:Q15375 xref: UniProtKB:Q59G40 xref: UniProtKB:Q5VTU0 xref: UniProtKB:Q8N368 xref: UniProtKB:Q9H124 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007496 ! EPHA7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034750 ! EPHA7_HUMAN-Phosphotyrosine608 relationship: transforms_into CCO:B0034751 ! EPHA7_HUMAN-Phosphotyrosine614 relationship: transforms_into CCO:B0034752 ! EPHA7_HUMAN-Phosphotyrosine791 relationship: transforms_into CCO:B0034753 ! EPHA7_HUMAN-Phosphotyrosine940 [Term] id: CCO:B0014962 name: A8CDT5_HUMAN def: "EphB6 variant protein" [UniProtKB:A8CDT5] xref: EMBL:ABV55388.1 xref: UniProtKB:A8CDT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0014963 name: Q8IUX6_HUMAN def: "EPH receptor A8" [UniProtKB:Q8IUX6] xref: EMBL:AAH38796.1 xref: EMBL:AAH72417.2 xref: EMBL:CAI22039.1 xref: UniProtKB:Q6IN80 xref: UniProtKB:Q8IUX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007497 ! EPHA8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0014967 name: EPHA3_HUMAN def: "Ephrin type-A receptor 3 precursor" [UniProtKB:P29320] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P29320] synonym: "HEK" EXACT [UniProtKB:P29320] synonym: "HEK4" EXACT [UniProtKB:P29320] synonym: "Tyrosine-protein kinase receptor ETK1" EXACT [UniProtKB:P29320] synonym: "Tyrosine-protein kinase TYRO4" EXACT [UniProtKB:P29320] xref: EMBL:AAA58633.1 xref: EMBL:AAG43576.1 xref: EMBL:AAG43577.1 xref: UniProtKB:P29320 xref: UniProtKB:Q9H2V3 xref: UniProtKB:Q9H2V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007492 ! EPHA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034734 ! EPHA3_HUMAN-Phosphotyrosine596 relationship: transforms_into CCO:B0034735 ! EPHA3_HUMAN-Phosphotyrosine602 relationship: transforms_into CCO:B0034736 ! EPHA3_HUMAN-Phosphotyrosine779 relationship: transforms_into CCO:B0034737 ! EPHA3_HUMAN-Phosphotyrosine937 [Term] id: CCO:B0014968 name: EPHB3_HUMAN def: "Ephrin type-B receptor 3 precursor" [UniProtKB:P54753] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P54753] synonym: "Tyrosine-protein kinase receptor HEK-2" EXACT [UniProtKB:P54753] synonym: "Tyrosine-protein kinase TYRO6" EXACT [UniProtKB:P54753] xref: EMBL:AAH52968.1 xref: EMBL:CAA53021.1 xref: UniProtKB:P54753 xref: UniProtKB:Q7Z740 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007500 ! EPHB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0017638 ! ephb3-npm_alk physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034760 ! EPHB3_HUMAN-Phosphotyrosine608 relationship: transforms_into CCO:B0034761 ! EPHB3_HUMAN-Phosphotyrosine614 relationship: transforms_into CCO:B0034762 ! EPHB3_HUMAN-Phosphotyrosine792 relationship: transforms_into CCO:B0034763 ! EPHB3_HUMAN-Phosphotyrosine942 relationship: transforms_into CCO:B0065089 ! EPHB3_HUMAN-Phosphotyrosine600 [Term] id: CCO:B0014969 name: EPHB1_HUMAN def: "Ephrin type-B receptor 1 precursor" [UniProtKB:P54762] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P54762] synonym: "ELK" EXACT [UniProtKB:P54762] synonym: "HEK6" EXACT [UniProtKB:P54762] synonym: "NET" EXACT [UniProtKB:P54762] synonym: "Tyrosine-protein kinase receptor EPH-2" EXACT [UniProtKB:P54762] xref: EMBL:AAB08520.1 xref: EMBL:AAB94627.1 xref: EMBL:AAB94628.1 xref: EMBL:AAD02030.1 xref: EMBL:AAD02031.1 xref: UniProtKB:O43569 xref: UniProtKB:O95142 xref: UniProtKB:O95143 xref: UniProtKB:P54762 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007499 ! EPHB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017907 ! ephb1-grb10-3 physical interaction relationship: participates_in CCO:I0018209 ! ephb1-grb10-2 physical interaction relationship: participates_in CCO:I0018210 ! ephb1-grb2-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034756 ! EPHB1_HUMAN-Phosphotyrosine594 relationship: transforms_into CCO:B0034757 ! EPHB1_HUMAN-Phosphotyrosine600 relationship: transforms_into CCO:B0034758 ! EPHB1_HUMAN-Phosphotyrosine778 relationship: transforms_into CCO:B0034759 ! EPHB1_HUMAN-Phosphotyrosine928 relationship: transforms_into CCO:B0039414 ! EPHB1_HUMAN-Phosphoserine968 [Term] id: CCO:B0014973 name: EPHA1_HUMAN def: "Ephrin type-A receptor 1 precursor" [UniProtKB:P21709] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P21709] synonym: "Tyrosine-protein kinase receptor EPH" EXACT [UniProtKB:P21709] xref: EMBL:AAA36747.1 xref: EMBL:AAD43440.1 xref: EMBL:AAS07458.1 xref: EMBL:CAA81796.1 xref: UniProtKB:P21709 xref: UniProtKB:Q15405 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007491 ! EPHA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0017631 ! npm_alk-pkc physical interaction relationship: participates_in CCO:I0017637 ! epha1-npm_alk physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034727 ! EPHA1_HUMAN-Phosphothreonine33 relationship: transforms_into CCO:B0034728 ! EPHA1_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0034729 ! EPHA1_HUMAN-Phosphotyrosine599 relationship: transforms_into CCO:B0034730 ! EPHA1_HUMAN-Phosphotyrosine605 relationship: transforms_into CCO:B0034731 ! EPHA1_HUMAN-Phosphotyrosine781 relationship: transforms_into CCO:B0034732 ! EPHA1_HUMAN-Phosphoserine910 relationship: transforms_into CCO:B0034733 ! EPHA1_HUMAN-Phosphotyrosine930 [Term] id: CCO:B0014982 name: TB182_HUMAN def: "182 kDa tankyrase 1-binding protein" [UniProtKB:Q9C0C2] xref: EMBL:AAH23622.1 xref: EMBL:AAM15531.1 xref: EMBL:BAB21832.2 xref: EMBL:BAB84939.1 xref: EMBL:BAC85989.1 xref: UniProtKB:Q6PJ35 xref: UniProtKB:Q6ZV74 xref: UniProtKB:Q9C0C2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008265 ! TNKS1BP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: transforms_into CCO:B0035724 ! TB182_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0035725 ! TB182_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0035726 ! TB182_HUMAN-Phosphoserine601 relationship: transforms_into CCO:B0035727 ! TB182_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0035728 ! TB182_HUMAN-Phosphoserine691 relationship: transforms_into CCO:B0035729 ! TB182_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0035730 ! TB182_HUMAN-Phosphoserine806 relationship: transforms_into CCO:B0035731 ! TB182_HUMAN-Phosphothreonine833 relationship: transforms_into CCO:B0035732 ! TB182_HUMAN-Phosphoserine836 relationship: transforms_into CCO:B0035733 ! TB182_HUMAN-Phosphoserine872 relationship: transforms_into CCO:B0035734 ! TB182_HUMAN-Phosphoserine893 relationship: transforms_into CCO:B0035735 ! TB182_HUMAN-Phosphoserine920 relationship: transforms_into CCO:B0035736 ! TB182_HUMAN-Phosphoserine936 relationship: transforms_into CCO:B0035737 ! TB182_HUMAN-Phosphoserine1093 relationship: transforms_into CCO:B0035738 ! TB182_HUMAN-Phosphoserine1103 relationship: transforms_into CCO:B0035739 ! TB182_HUMAN-Phosphoserine1138 relationship: transforms_into CCO:B0035740 ! TB182_HUMAN-Phosphoserine1248 relationship: transforms_into CCO:B0035741 ! TB182_HUMAN-Phosphoserine1331 relationship: transforms_into CCO:B0035742 ! TB182_HUMAN-Phosphoserine1383 relationship: transforms_into CCO:B0035743 ! TB182_HUMAN-Phosphoserine1385 relationship: transforms_into CCO:B0035744 ! TB182_HUMAN-Phosphoserine1452 relationship: transforms_into CCO:B0035745 ! TB182_HUMAN-Phosphoserine1554 relationship: transforms_into CCO:B0035746 ! TB182_HUMAN-Phosphoserine1620 relationship: transforms_into CCO:B0035747 ! TB182_HUMAN-Phosphoserine1621 relationship: transforms_into CCO:B0035748 ! TB182_HUMAN-Phosphoserine1654 relationship: transforms_into CCO:B0035749 ! TB182_HUMAN-Phosphoserine1666 relationship: transforms_into CCO:B0052814 ! TB182_HUMAN-Phosphoserine1024 relationship: transforms_into CCO:B0052815 ! TB182_HUMAN-Phosphoserine1029 relationship: transforms_into CCO:B0071174 ! TB182_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0071175 ! TB182_HUMAN-Phosphothreonine239 relationship: transforms_into CCO:B0071176 ! TB182_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0071177 ! TB182_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0071178 ! TB182_HUMAN-Phosphoserine429 relationship: transforms_into CCO:B0071179 ! TB182_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0071180 ! TB182_HUMAN-Phosphoserine494 relationship: transforms_into CCO:B0071181 ! TB182_HUMAN-Phosphoserine498 relationship: transforms_into CCO:B0071182 ! TB182_HUMAN-Phosphoserine712 relationship: transforms_into CCO:B0071183 ! TB182_HUMAN-Phosphoserine744 relationship: transforms_into CCO:B0071184 ! TB182_HUMAN-Phosphoserine762 relationship: transforms_into CCO:B0071185 ! TB182_HUMAN-Phosphoserine976 relationship: transforms_into CCO:B0071186 ! TB182_HUMAN-Phosphothreonine979 relationship: transforms_into CCO:B0071187 ! TB182_HUMAN-Phosphoserine983 relationship: transforms_into CCO:B0071188 ! TB182_HUMAN-Phosphoserine987 relationship: transforms_into CCO:B0071189 ! TB182_HUMAN-Phosphoserine1008 relationship: transforms_into CCO:B0071190 ! TB182_HUMAN-Phosphoserine1133 relationship: transforms_into CCO:B0071191 ! TB182_HUMAN-Phosphoserine1178 relationship: transforms_into CCO:B0071192 ! TB182_HUMAN-Phosphoserine1181 relationship: transforms_into CCO:B0071193 ! TB182_HUMAN-Phosphothreonine1282 relationship: transforms_into CCO:B0071194 ! TB182_HUMAN-Phosphoserine1297 relationship: transforms_into CCO:B0071195 ! TB182_HUMAN-Phosphoserine1328 relationship: transforms_into CCO:B0071196 ! TB182_HUMAN-Phosphoserine1405 relationship: transforms_into CCO:B0071197 ! TB182_HUMAN-Phosphoserine1439 relationship: transforms_into CCO:B0071198 ! TB182_HUMAN-Phosphoserine1473 relationship: transforms_into CCO:B0071199 ! TB182_HUMAN-Phosphoserine1476 relationship: transforms_into CCO:B0071200 ! TB182_HUMAN-Phosphoserine1533 relationship: transforms_into CCO:B0071201 ! TB182_HUMAN-Phosphoserine1545 relationship: transforms_into CCO:B0071202 ! TB182_HUMAN-Phosphoserine1552 relationship: transforms_into CCO:B0071203 ! TB182_HUMAN-Phosphoserine1558 relationship: transforms_into CCO:B0071204 ! TB182_HUMAN-Phosphothreonine1563 relationship: transforms_into CCO:B0071205 ! TB182_HUMAN-Phosphoserine1652 [Term] id: CCO:B0015018 name: PPIP1_HUMAN def: "Proline-serine-threonine phosphatase-interacting protein 1" [UniProtKB:O43586] synonym: "CD2-binding protein 1" EXACT [UniProtKB:O43586] synonym: "H-PIP" EXACT [UniProtKB:O43586] synonym: "PEST phosphatase-interacting protein 1" EXACT [UniProtKB:O43586] xref: EMBL:AAD00762.1 xref: EMBL:AAD11958.1 xref: EMBL:AAD11959.1 xref: EMBL:AAH08602.1 xref: UniProtKB:O43585 xref: UniProtKB:O43586 xref: UniProtKB:O95657 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008005 ! PSTPIP1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0015065 name: CRTAM_HUMAN def: "Cytotoxic and regulatory T-cell molecule precursor" [UniProtKB:O95727] synonym: "Class-I MHC-restricted T-cell-associated molecule" EXACT [UniProtKB:O95727] xref: EMBL:AAC80267.1 xref: EMBL:AAH70266.1 xref: EMBL:BAD93067.1 xref: UniProtKB:O95727 xref: UniProtKB:Q59EI1 xref: UniProtKB:Q6IRX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007427 ! CRTAM_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000605 ! positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target relationship: participates_in CCO:P0002637 ! positive regulation of natural killer cell mediated cytotoxicity [Term] id: CCO:B0015066 name: FOXN2_HUMAN def: "Forkhead box protein N2" [UniProtKB:P32314] synonym: "Human T-cell leukemia virus enhancer factor" EXACT [UniProtKB:P32314] xref: EMBL:AAB03504.1 xref: EMBL:AAH63305.1 xref: EMBL:AAY14813.1 xref: UniProtKB:P32314 xref: UniProtKB:Q15769 xref: UniProtKB:Q6P4Q2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007550 ! FOXN2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015067 name: Q6P4Q2_HUMAN xref: UniProtKB:Q6P4Q2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015073 name: RBMS1_HUMAN def: "RNA-binding motif, single-stranded-interacting protein 1" [UniProtKB:P29558] synonym: "Single-stranded DNA-binding protein MSSP-1" EXACT [UniProtKB:P29558] synonym: "Suppressor of CDC2 with RNA-binding motif 2" EXACT [UniProtKB:P29558] xref: EMBL:AAH12992.1 xref: EMBL:AAH12993.1 xref: EMBL:AAH18951.1 xref: EMBL:BAA05841.1 xref: EMBL:CAA45923.1 xref: UniProtKB:P29558 xref: UniProtKB:Q15433 xref: UniProtKB:Q8WV20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008065 ! RBMS1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0069824 ! RBMS1_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0069825 ! RBMS1_HUMAN-Phosphothreonine208 [Term] id: CCO:B0015090 name: Q5QPR4_HUMAN def: "Cell division cycle 2-like 2 (PITSLRE proteins)" [UniProtKB:Q5QPR4] xref: EMBL:CAI20030.1 xref: UniProtKB:Q5QPR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004274 ! CDC2L2_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0015092 name: Q5QPR3_HUMAN def: "Cell division cycle 2-like 2 (PITSLRE proteins)" [UniProtKB:Q5QPR3] xref: EMBL:CAI20031.1 xref: UniProtKB:Q5QPR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004274 ! CDC2L2_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0015122 name: GLR_HUMAN def: "Glucagon receptor precursor" [UniProtKB:P47871] synonym: "GL-R" EXACT [UniProtKB:P47871] xref: EMBL:AAA35897.1 xref: EMBL:AAA53628.1 xref: EMBL:AAC52063.1 xref: EMBL:AAI04855.1 xref: EMBL:AAI12042.1 xref: UniProtKB:P47871 xref: UniProtKB:Q2M3M5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017934 ! GCGR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001308 ! glucagon receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0015123 name: GLP1R_HUMAN def: "Glucagon-like peptide 1 receptor precursor" [UniProtKB:P43220] synonym: "GLP-1 receptor" EXACT [UniProtKB:P43220] synonym: "GLP-1-R" EXACT [UniProtKB:P43220] synonym: "GLP-1R" EXACT [UniProtKB:P43220] xref: EMBL:AAA03614.1 xref: EMBL:AAA17021.1 xref: EMBL:AAA62471.1 xref: EMBL:AAA63787.1 xref: EMBL:AAB64013.1 xref: EMBL:AAC50050.1 xref: EMBL:AAI12127.1 xref: EMBL:AAI13494.1 xref: EMBL:AAR05444.1 xref: EMBL:BAC05908.1 xref: EMBL:CAB71177.1 xref: UniProtKB:P43220 xref: UniProtKB:Q2M229 xref: UniProtKB:Q99669 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017930 ! GLP1R_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001308 ! glucagon receptor activity relationship: has_function CCO:F0001980 ! peptide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001149 ! cAMP-mediated signaling [Term] id: CCO:B0015124 name: GIPR_HUMAN def: "Gastric inhibitory polypeptide receptor precursor" [UniProtKB:P48546] synonym: "GIP-R" EXACT [UniProtKB:P48546] synonym: "Glucose-dependent insulinotropic polypeptide receptor" EXACT [UniProtKB:P48546] xref: EMBL:AAA84418.1 xref: EMBL:AAB35419.2 xref: EMBL:AAC97984.1 xref: EMBL:AAD22674.1 xref: EMBL:AAH93723.1 xref: EMBL:AAI01674.1 xref: EMBL:BAA08503.1 xref: EMBL:CAA57426.1 xref: UniProtKB:P48546 xref: UniProtKB:Q14401 xref: UniProtKB:Q16400 xref: UniProtKB:Q52M04 xref: UniProtKB:Q9UPI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017923 ! GIPR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003194 ! gastric inhibitory peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0015126 name: Q8NHB4_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHB4] xref: EMBL:BAC05721.1 xref: UniProtKB:Q8NHB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001329 ! parathyroid hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0015129 name: Q6ZN22_HUMAN def: "cDNA FLJ16511 fis, clone HEART2009680, highly similar to Vasoactive intestinal polypeptide receptor 2" [UniProtKB:Q6ZN22] xref: EMBL:BAD18553.1 xref: UniProtKB:Q6ZN22 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0015134 name: GLP2R_HUMAN def: "Glucagon-like peptide 2 receptor precursor" [UniProtKB:O95838] synonym: "GLP-2 receptor" EXACT [UniProtKB:O95838] synonym: "GLP-2-R" EXACT [UniProtKB:O95838] synonym: "GLP-2R" EXACT [UniProtKB:O95838] xref: EMBL:AAD16895.1 xref: EMBL:AAH96262.1 xref: UniProtKB:O95838 xref: UniProtKB:Q4VAT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017932 ! GLP2R_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0015136 name: SCTR_HUMAN def: "Secretin receptor precursor" [UniProtKB:P47872] synonym: "SCT-R" EXACT [UniProtKB:P47872] xref: EMBL:AAA64949.1 xref: EMBL:AAA87556.1 xref: EMBL:AAC50106.1 xref: EMBL:AAR25625.1 xref: EMBL:BAC05886.1 xref: UniProtKB:P47872 xref: UniProtKB:Q12961 xref: UniProtKB:Q13213 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019854 ! SCTR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_function CCO:F0002548 ! secretin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0015164 name: HHIP_HUMAN def: "Hedgehog-interacting protein precursor" [UniProtKB:Q96QV1] synonym: "HHIP" EXACT [UniProtKB:Q96QV1] synonym: "HIP" EXACT [UniProtKB:Q96QV1] xref: EMBL:AAG34731.1 xref: EMBL:AAG35411.1 xref: EMBL:AAH09298.1 xref: EMBL:AAH25311.1 xref: EMBL:AAK18182.1 xref: EMBL:AAQ89107.1 xref: EMBL:BAB14945.1 xref: EMBL:BAC11154.1 xref: UniProtKB:Q6PK09 xref: UniProtKB:Q8NCI7 xref: UniProtKB:Q96QV1 xref: UniProtKB:Q9BXK3 xref: UniProtKB:Q9H1J4 xref: UniProtKB:Q9H7E7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018130 ! HHIP_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0002026 ! regulation of fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0002586 ! negative regulation of smoothened signaling pathway [Term] id: CCO:B0015232 name: Q9NSP8_HUMAN xref: UniProtKB:Q9NSP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0015235 name: Q8IVV0_HUMAN xref: UniProtKB:Q8IVV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0015238 name: FOXK2_HUMAN def: "Forkhead box protein K2" [UniProtKB:Q01167] synonym: "Cellular transcription factor ILF-1" EXACT [UniProtKB:Q01167] synonym: "FOXK1" EXACT [UniProtKB:Q01167] synonym: "Interleukin enhancer-binding factor 1" EXACT [UniProtKB:Q01167] xref: EMBL:AAB02820.1 xref: EMBL:AAB02821.1 xref: EMBL:AAB02822.1 xref: EMBL:CAA43200.1 xref: UniProtKB:A6NEP5 xref: UniProtKB:Q01167 xref: UniProtKB:Q13622 xref: UniProtKB:Q13623 xref: UniProtKB:Q13624 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011394 ! FOXK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0039434 ! FOXK2_HUMAN-Phosphoserine61 relationship: transforms_into CCO:B0039435 ! FOXK2_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0039436 ! FOXK2_HUMAN-Phosphoserine398 relationship: transforms_into CCO:B0052388 ! FOXK2_HUMAN-Phosphoserine428 [Term] id: CCO:B0015239 name: FOXK1_HUMAN def: "Forkhead box protein K1" [UniProtKB:P85037] synonym: "MNF" EXACT [UniProtKB:P85037] synonym: "Myocyte nuclear factor" EXACT [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011393 ! FOXK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039425 ! FOXK1_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0039426 ! FOXK1_HUMAN-Phosphoserine223 relationship: transforms_into CCO:B0039427 ! FOXK1_HUMAN-Phosphoserine416 relationship: transforms_into CCO:B0039428 ! FOXK1_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0039429 ! FOXK1_HUMAN-Phosphothreonine422 relationship: transforms_into CCO:B0039430 ! FOXK1_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0039431 ! FOXK1_HUMAN-Phosphothreonine436 relationship: transforms_into CCO:B0039432 ! FOXK1_HUMAN-Phosphoserine441 relationship: transforms_into CCO:B0039433 ! FOXK1_HUMAN-Phosphoserine445 relationship: transforms_into CCO:B0052386 ! FOXK1_HUMAN-Phosphothreonine245 relationship: transforms_into CCO:B0052387 ! FOXK1_HUMAN-Phosphothreonine247 relationship: transforms_into CCO:B0066260 ! FOXK1_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0066261 ! FOXK1_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0066262 ! FOXK1_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0066263 ! FOXK1_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0066264 ! FOXK1_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0066265 ! FOXK1_HUMAN-Phosphoserine455 [Term] id: CCO:B0015243 name: TCEA3_HUMAN def: "Transcription elongation factor A protein 3" [UniProtKB:O75764] synonym: "Transcription elongation factor S-II protein 3" EXACT [UniProtKB:O75764] synonym: "Transcription elongation factor TFIIS.h" EXACT [UniProtKB:O75764] xref: EMBL:AAH41613.1 xref: EMBL:CAA11393.1 xref: UniProtKB:O75764 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020211 ! TCEA3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0015270 name: DFFB_HUMAN def: "DNA fragmentation factor subunit beta" [UniProtKB:O76075] synonym: "CAD" EXACT [UniProtKB:O76075] synonym: "Caspase-activated deoxyribonuclease" EXACT [UniProtKB:O76075] synonym: "Caspase-activated DNase" EXACT [UniProtKB:O76075] synonym: "Caspase-activated nuclease" EXACT [UniProtKB:O76075] synonym: "CPAN" EXACT [UniProtKB:O76075] synonym: "DFF-40" EXACT [UniProtKB:O76075] synonym: "DNA fragmentation factor 40 kDa subunit" EXACT [UniProtKB:O76075] synonym: "EC 3.-.-.-" EXACT [UniProtKB:O76075] xref: EMBL:AAC39709.1 xref: EMBL:AAC39920.1 xref: EMBL:AAH48797.1 xref: EMBL:BAA32250.1 xref: EMBL:BAB40447.1 xref: EMBL:BAB40448.1 xref: EMBL:BAB40449.1 xref: UniProtKB:O60521 xref: UniProtKB:O76075 xref: UniProtKB:Q9BYI4 xref: UniProtKB:Q9BYI5 xref: UniProtKB:Q9BYI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007456 ! DFFB_human relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000933 ! caspase-activated deoxyribonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001251 ! apoptotic chromosome condensation [Term] id: CCO:B0015284 name: ARF3_HUMAN def: "ADP-ribosylation factor 3" [UniProtKB:P61204] xref: EMBL:AAA58359.1 xref: EMBL:AAA83931.1 xref: EMBL:AAB59425.1 xref: EMBL:AAH07647.1 xref: EMBL:AAH07762.1 xref: EMBL:AAH17565.1 xref: EMBL:AAH28402.1 xref: EMBL:AAM12596.1 xref: EMBL:AAP35316.1 xref: UniProtKB:P16587 xref: UniProtKB:P61204 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017004 ! ARF3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:I0018664 ! arf3-arfip2-1 physical interaction relationship: participates_in CCO:I0018934 ! atn1-arf3 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0015288 name: ARF1_HUMAN def: "ADP-ribosylation factor 1" [UniProtKB:P84077] xref: EMBL:AAA35511.1 xref: EMBL:AAA35512.1 xref: EMBL:AAA35552.1 xref: EMBL:AAC09356.1 xref: EMBL:AAC28623.1 xref: EMBL:AAH09247.1 xref: EMBL:AAH10429.1 xref: EMBL:AAH11358.1 xref: EMBL:AAM12595.1 xref: EMBL:AAP36057.1 xref: EMBL:CAI23120.1 xref: UniProtKB:P10947 xref: UniProtKB:P32889 xref: UniProtKB:P84077 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017003 ! ARF1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000933 ! sarcomere relationship: participates_in CCO:I0015899 ! arf1-pscd2-1 physical interaction relationship: participates_in CCO:I0015900 ! arf1-pscd2-2 physical interaction relationship: participates_in CCO:I0017852 ! gga1-arf1-1 physical interaction relationship: participates_in CCO:I0018148 ! arf1-pscd2-3 direct interaction relationship: participates_in CCO:I0018149 ! arf1-pscd2-4 direct interaction relationship: participates_in CCO:I0019649 ! arf1-eef1g physical interaction relationship: participates_in CCO:I0019895 ! arf1-wbp11 physical interaction relationship: participates_in CCO:I0020228 ! arf1-c4orf14 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0065698 ! ARF1_HUMAN-Phosphoserine147 [Term] id: CCO:B0015391 name: RL31_HUMAN def: "60S ribosomal protein L31" [UniProtKB:P62899] xref: EMBL:AAH17343.1 xref: EMBL:AAH70373.1 xref: EMBL:AAY14823.1 xref: EMBL:BAB79468.1 xref: EMBL:CAA34066.1 xref: EMBL:CAA48925.1 xref: UniProtKB:P12947 xref: UniProtKB:P62899 xref: UniProtKB:Q53SQ5 xref: UniProtKB:Q6LBJ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022576 ! RPL31_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015325 ! ewsr1-rpl31 physical interaction relationship: transforms_into CCO:B0070082 ! RL31_HUMAN-Phosphoserine98 relationship: transforms_into CCO:B0070083 ! RL31_HUMAN-Phosphotyrosine103 relationship: transforms_into CCO:B0070084 ! RL31_HUMAN-Phosphotyrosine108 [Term] id: CCO:B0015397 name: Q9H7H9_HUMAN def: "FLJ00110 protein" [UniProtKB:Q9H7H9] xref: EMBL:BAB15791.1 xref: UniProtKB:Q9H7H9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021264 ! FLJ00110_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0015398 name: MXI1_HUMAN def: "MAX-interacting protein 1" [UniProtKB:P50539] synonym: "Protein MXI1" EXACT [UniProtKB:P50539] xref: EMBL:AAA75508.1 xref: EMBL:AAC50446.1 xref: EMBL:AAD14282.1 xref: EMBL:BAA09972.1 xref: EMBL:CAG38813.1 xref: EMBL:CAI15476.1 xref: EMBL:CAI15479.1 xref: UniProtKB:P50539 xref: UniProtKB:Q15887 xref: UniProtKB:Q6FHW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018686 ! MXI1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0015399 name: MAD4_HUMAN def: "Max-interacting transcriptional repressor MAD4" [UniProtKB:Q14582] synonym: "MAX dimerization protein 4" EXACT [UniProtKB:Q14582] synonym: "Max-associated protein 4" EXACT [UniProtKB:Q14582] xref: EMBL:AAB97009.1 xref: EMBL:AAF98553.1 xref: EMBL:AAH68060.1 xref: EMBL:AAV38772.1 xref: EMBL:AAV38773.1 xref: EMBL:CAA89217.1 xref: EMBL:CAM20460.1 xref: UniProtKB:A2A335 xref: UniProtKB:Q14582 xref: UniProtKB:Q5TZX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018556 ! MXD4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0015400 name: MAD1_HUMAN def: "MAD protein" [UniProtKB:Q05195] synonym: "MAX dimerization protein 1" EXACT [UniProtKB:Q05195] synonym: "MAX dimerizer" EXACT [UniProtKB:Q05195] xref: EMBL:AAA36194.1 xref: EMBL:AAH69377.1 xref: EMBL:AAH69433.1 xref: EMBL:AAH98396.1 xref: EMBL:AAI13532.1 xref: EMBL:AAI17261.1 xref: EMBL:AAY14867.1 xref: EMBL:CAG38734.1 xref: EMBL:CAG46493.1 xref: UniProtKB:Q05195 xref: UniProtKB:Q6FI41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018554 ! MXD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0015493 name: SUV42_HUMAN def: "Histone-lysine N-methyltransferase SUV420H2" [UniProtKB:Q86Y97] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q86Y97] synonym: "Lysine N-methyltransferase 5C" EXACT [UniProtKB:Q86Y97] synonym: "Su(var)4-20 homolog 2" EXACT [UniProtKB:Q86Y97] synonym: "Suppressor of variegation 4-20 homolog 2" EXACT [UniProtKB:Q86Y97] synonym: "Suv4-20h2" EXACT [UniProtKB:Q86Y97] xref: EMBL:AAH05842.1 xref: EMBL:AAH19313.1 xref: EMBL:AAH44889.1 xref: EMBL:AAL55766.1 xref: UniProtKB:Q86Y97 xref: UniProtKB:Q8WZ10 xref: UniProtKB:Q9BRZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008254 ! SUV420H2_human relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015494 name: SUV41_HUMAN def: "Histone-lysine N-methyltransferase SUV420H1" [UniProtKB:Q4FZB7] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q4FZB7] synonym: "Lysine N-methyltransferase 5B" EXACT [UniProtKB:Q4FZB7] synonym: "Su(var)4-20 homolog 1" EXACT [UniProtKB:Q4FZB7] synonym: "Suppressor of variegation 4-20 homolog 1" EXACT [UniProtKB:Q4FZB7] synonym: "Suv4-20h1" EXACT [UniProtKB:Q4FZB7] xref: EMBL:AAD34080.1 xref: EMBL:AAG36937.1 xref: EMBL:AAH02522.2 xref: EMBL:AAH12933.1 xref: EMBL:AAH65287.1 xref: EMBL:AAH87834.1 xref: EMBL:AAH98121.1 xref: EMBL:AAH99714.1 xref: EMBL:AAI03499.1 xref: EMBL:AAI04484.1 xref: EMBL:BAA90905.1 xref: EMBL:CAC21680.1 xref: UniProtKB:Q3SX56 xref: UniProtKB:Q4FZB7 xref: UniProtKB:Q4V775 xref: UniProtKB:Q6P150 xref: UniProtKB:Q96E44 xref: UniProtKB:Q9BUL0 xref: UniProtKB:Q9H022 xref: UniProtKB:Q9H2K3 xref: UniProtKB:Q9NXV3 xref: UniProtKB:Q9Y393 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008253 ! SUV420H1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015543 name: SMAP1_HUMAN def: "Stromal membrane-associated protein 1" [UniProtKB:Q8IYB5] xref: EMBL:AAH08672.1 xref: EMBL:AAH28074.1 xref: EMBL:AAH36123.1 xref: EMBL:AAL14714.1 xref: EMBL:AAL14715.1 xref: EMBL:AAL14716.1 xref: EMBL:AAL14717.1 xref: EMBL:AAP97320.1 xref: EMBL:BAB14473.1 xref: EMBL:BAD96431.1 xref: EMBL:CAD38762.1 xref: EMBL:CAI12310.1 xref: EMBL:CAI12311.1 xref: EMBL:CAI12312.1 xref: EMBL:CAI14240.1 xref: EMBL:CAI14241.1 xref: EMBL:CAI14242.1 xref: EMBL:CAI42146.1 xref: EMBL:CAI42147.1 xref: EMBL:CAI42148.1 xref: UniProtKB:Q53H70 xref: UniProtKB:Q5SYQ2 xref: UniProtKB:Q6PK24 xref: UniProtKB:Q8IYB5 xref: UniProtKB:Q8NDH4 xref: UniProtKB:Q96L38 xref: UniProtKB:Q96L39 xref: UniProtKB:Q9H8X4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008187 ! SMAP1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0015556 name: Q86UH8_HUMAN def: "Pol protein" [UniProtKB:Q86UH8] xref: EMBL:AAP29639.1 xref: UniProtKB:Q86UH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000659 ! aspartic-type endopeptidase activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0015573 name: ST38L_HUMAN def: "Serine/threonine-protein kinase 38-like" [UniProtKB:Q9Y2H1] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y2H1] synonym: "NDR2 protein kinase" EXACT [UniProtKB:Q9Y2H1] synonym: "Nuclear Dbf2-related kinase 2" EXACT [UniProtKB:Q9Y2H1] xref: EMBL:AAH28603.1 xref: EMBL:BAA76809.2 xref: EMBL:BAF83744.1 xref: EMBL:EAW96549.1 xref: UniProtKB:A8K4U0 xref: UniProtKB:Q8TBX7 xref: UniProtKB:Q9Y2H1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008238 ! STK38L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018097 ! stk38l-mobk1b-1 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: transforms_into CCO:B0035695 ! ST38L_HUMAN-Phosphothreonine75 relationship: transforms_into CCO:B0035696 ! ST38L_HUMAN-Phosphoserine282 relationship: transforms_into CCO:B0035697 ! ST38L_HUMAN-Phosphothreonine442 relationship: transforms_into CCO:B0035698 ! ST38L_HUMAN-Phosphothreonine450 relationship: transforms_into CCO:B0043381 ! ST38L_HUMAN-N-acetylalanine2 [Term] id: CCO:B0015584 name: STK38_HUMAN def: "Serine/threonine-protein kinase 38" [UniProtKB:Q15208] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q15208] synonym: "NDR1 protein kinase" EXACT [UniProtKB:Q15208] synonym: "Nuclear Dbf2-related kinase 1" EXACT [UniProtKB:Q15208] xref: EMBL:AAH12085.1 xref: EMBL:AAH95413.1 xref: EMBL:CAA84485.1 xref: EMBL:CAB39180.1 xref: UniProtKB:Q15208 xref: UniProtKB:Q503A1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008246 ! STK38_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017935 ! stk38-mobk1b-1 physical interaction relationship: participates_in CCO:I0017936 ! mobk1b-stk38-1 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0035709 ! STK38_HUMAN-Phosphothreonine74 relationship: transforms_into CCO:B0035710 ! STK38_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0035711 ! STK38_HUMAN-Phosphothreonine444 relationship: transforms_into CCO:B0039660 ! STK38_HUMAN-Phosphothreonine26 relationship: transforms_into CCO:B0043383 ! STK38_HUMAN-N-acetylalanine2 [Term] id: CCO:B0015628 name: ACTG_HUMAN def: "Actin, cytoplasmic 2" [UniProtKB:P63261] synonym: "Gamma-actin" EXACT [UniProtKB:P63261] xref: EMBL:AAA51579.1 xref: EMBL:AAA51580.1 xref: EMBL:AAH00292.1 xref: EMBL:AAH01920.1 xref: EMBL:AAH07442.1 xref: EMBL:AAH09848.1 xref: EMBL:AAH10999.1 xref: EMBL:AAH12050.1 xref: EMBL:AAH15005.1 xref: EMBL:AAH15695.1 xref: EMBL:AAH15779.1 xref: EMBL:AAH18774.1 xref: EMBL:AAH53572.1 xref: EMBL:AAV38659.1 xref: EMBL:CAA27723.1 xref: UniProtKB:P02571 xref: UniProtKB:P14104 xref: UniProtKB:P63261 xref: UniProtKB:P99022 xref: UniProtKB:Q5U032 xref: UniProtKB:Q96E67 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007206 ! ACTG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015123 ! actg1-cfl1 physical interaction relationship: participates_in CCO:I0015597 ! actg1-dstn physical interaction relationship: participates_in CCO:I0016359 ! rel-actg1 physical interaction relationship: participates_in CCO:I0016378 ! nfkbia-actg1 physical interaction relationship: participates_in CCO:I0016399 ! nfkbib-actg1 physical interaction relationship: participates_in CCO:I0016437 ! chuk-actg1 physical interaction relationship: participates_in CCO:I0016458 ! ikbkb-actg1 physical interaction relationship: participates_in CCO:I0016472 ! ikbke-actg1 physical interaction relationship: participates_in CCO:I0016521 ! ikbkg-actg1 physical interaction relationship: participates_in CCO:I0016614 ! map3k1-actg1 physical interaction relationship: participates_in CCO:I0016704 ! map3k3-actg1 physical interaction relationship: participates_in CCO:I0016870 ! relb-actg1 physical interaction relationship: participates_in CCO:I0016901 ! ripk1-actg1 physical interaction relationship: participates_in CCO:I0016909 ! ripk2-actg1 physical interaction relationship: participates_in CCO:I0016948 ! q9nyj8-actg1 physical interaction relationship: participates_in CCO:I0017007 ! tnfrsf1a-actg1 physical interaction relationship: participates_in CCO:I0017070 ! tradd-actg1 physical interaction relationship: participates_in CCO:I0017097 ! traf1-actg1 physical interaction relationship: participates_in CCO:I0017123 ! traf2-actg1 physical interaction relationship: participates_in CCO:I0017141 ! traf6-actg1 physical interaction relationship: participates_in CCO:I0019558 ! actg1-pfn2 physical interaction relationship: participates_in CCO:I0019643 ! actg1-sh3gl2 physical interaction relationship: participates_in CCO:I0019746 ! itgb3bp-actg1 physical interaction relationship: transforms_into CCO:B0034502 ! ACTG_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0034503 ! ACTG_HUMAN-N-acetylglutamate2 relationship: transforms_into CCO:B0034504 ! ACTG_HUMAN-Tele-methylhistidine73 relationship: transforms_into CCO:B0034505 ! ACTG_HUMAN-Phosphotyrosine169 relationship: transforms_into CCO:B0043186 ! ACTG_HUMAN-Phosphothreonine318 relationship: transforms_into CCO:B0065396 ! ACTG_HUMAN-Phosphotyrosine198 relationship: transforms_into CCO:B0065397 ! ACTG_HUMAN-Phosphotyrosine294 [Term] id: CCO:B0015638 name: ACTC_HUMAN def: "Actin, alpha cardiac muscle 1" [UniProtKB:P68032] synonym: "Alpha-cardiac actin" EXACT [UniProtKB:P68032] xref: EMBL:AAB59619.1 xref: EMBL:AAH09978.1 xref: EMBL:CAG46594.1 xref: UniProtKB:P04270 xref: UniProtKB:P68032 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007205 ! ACTC1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003516 ! myosin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000933 ! sarcomere relationship: located_in CCO:C0001328 ! I band relationship: located_in CCO:C0001676 ! actomyosin, actin part relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0034500 ! ACTC_HUMAN-N-acetylaspartate3 relationship: transforms_into CCO:B0034501 ! ACTC_HUMAN-Tele-methylhistidine75 [Term] id: CCO:B0015644 name: ACTH_HUMAN def: "Actin, gamma-enteric smooth muscle" [UniProtKB:P63267] synonym: "Alpha-actin-3" EXACT [UniProtKB:P63267] synonym: "Gamma-2-actin" EXACT [UniProtKB:P63267] synonym: "Smooth muscle gamma-actin" EXACT [UniProtKB:P63267] xref: EMBL:AAH12617.1 xref: EMBL:AAH94877.1 xref: EMBL:AAX88909.1 xref: EMBL:BAA00546.1 xref: EMBL:CAA34814.1 xref: EMBL:CAG38753.1 xref: EMBL:CAG46593.1 xref: UniProtKB:P12718 xref: UniProtKB:P63267 xref: UniProtKB:Q504R1 xref: UniProtKB:Q6FI22 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007207 ! ACTG2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0034506 ! ACTH_HUMAN-N-acetylglutamate3 [Term] id: CCO:B0015646 name: ERCC1_HUMAN def: "DNA excision repair protein ERCC-1" [UniProtKB:P07992] xref: EMBL:AAA35810.1 xref: EMBL:AAA52394.1 xref: EMBL:AAA52395.1 xref: EMBL:AAC16253.1 xref: EMBL:AAH08930.1 xref: EMBL:AAM34796.1 xref: EMBL:AAV38609.1 xref: UniProtKB:P07992 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007501 ! ERCC1_human relationship: has_function CCO:F0000005 ! single-stranded DNA specific endodeoxyribonuclease activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0005878 ! structure-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000003 ! nucleotide-excision repair complex relationship: located_in CCO:C0000111 ! nuclear chromosome, telomeric region relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0015671 ! ercc1-sb132 physical interaction relationship: participates_in CCO:P0001547 ! negative regulation of telomere maintenance [Term] id: CCO:B0015655 name: HIPK3_HUMAN def: "Homeodomain-interacting protein kinase 3" [UniProtKB:Q9H422] synonym: "Androgen receptor-interacting nuclear protein kinase" EXACT [UniProtKB:Q9H422] synonym: "ANPK" EXACT [UniProtKB:Q9H422] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9H422] synonym: "Fas-interacting serine/threonine-protein kinase" EXACT [UniProtKB:Q9H422] synonym: "FIST" EXACT [UniProtKB:Q9H422] synonym: "Homolog of protein kinase YAK1" EXACT [UniProtKB:Q9H422] xref: EMBL:AAC64294.1 xref: EMBL:AAG25990.1 xref: EMBL:CAA70489.1 xref: EMBL:CAC13164.1 xref: EMBL:CAJ55828.1 xref: UniProtKB:O14632 xref: UniProtKB:Q2PBG4 xref: UniProtKB:Q2PBG5 xref: UniProtKB:Q92632 xref: UniProtKB:Q9H422 xref: UniProtKB:Q9HAS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018133 ! HIPK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0066805 ! HIPK3_HUMAN-Phosphotyrosine359 [Term] id: CCO:B0015672 name: NRCAM_HUMAN def: "Neuronal cell adhesion molecule precursor" [UniProtKB:Q92823] synonym: "hBravo" EXACT [UniProtKB:Q92823] synonym: "Ng-CAM-related" EXACT [UniProtKB:Q92823] synonym: "NgCAM-related cell adhesion molecule" EXACT [UniProtKB:Q92823] synonym: "Nr-CAM" EXACT [UniProtKB:Q92823] xref: EMBL:AAC50765.1 xref: EMBL:AAF22282.1 xref: EMBL:AAF22283.1 xref: EMBL:BAA20801.2 xref: EMBL:CAA04504.1 xref: EMBL:CAA04507.1 xref: EMBL:CAD97960.1 xref: EMBL:EAL24386.1 xref: EMBL:EAW83429.1 xref: UniProtKB:A4D0S3 xref: UniProtKB:O15051 xref: UniProtKB:O15179 xref: UniProtKB:Q92823 xref: UniProtKB:Q9UHI3 xref: UniProtKB:Q9UHI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007898 ! NRCAM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017278 ! nrcam-hspa12a-1 physical interaction relationship: participates_in CCO:I0017280 ! nrcam-hspa12a physical interaction relationship: participates_in CCO:P0001276 ! regulation of axon extension relationship: participates_in CCO:P0002480 ! positive regulation of neuron differentiation relationship: transforms_into CCO:B0035307 ! NRCAM_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0035308 ! NRCAM_HUMAN-Phosphoserine1295 [Term] id: CCO:B0015673 name: CHL1_HUMAN def: "Neural cell adhesion molecule L1-like protein precursor" [UniProtKB:O00533] synonym: "Close homolog of L1" EXACT [UniProtKB:O00533] xref: EMBL:AAB60937.1 xref: EMBL:AAI04919.1 xref: EMBL:BAD92566.1 xref: UniProtKB:O00533 xref: UniProtKB:Q2M3G2 xref: UniProtKB:Q59FY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007390 ! CHL1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0015682 name: EI2BA_HUMAN def: "Translation initiation factor eIF-2B subunit alpha" [UniProtKB:Q14232] synonym: "eIF-2B GDP-GTP exchange factor subunit alpha" EXACT [UniProtKB:Q14232] xref: EMBL:AAI03764.1 xref: EMBL:AAI04189.1 xref: EMBL:AAI04190.1 xref: EMBL:CAA64950.1 xref: EMBL:CAG33112.1 xref: EMBL:EAW98424.1 xref: UniProtKB:A6NLY9 xref: UniProtKB:Q14232 xref: UniProtKB:Q3SXP4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022214 ! EIF2B1_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000417 ! eukaryotic translation initiation factor 2B complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0018487 ! eif2b1-adrb2-3 colocalization relationship: participates_in CCO:I0019489 ! eif2b1-adrb2-2 physical interaction relationship: participates_in CCO:I0019559 ! arf4l-eif2b1 physical interaction [Term] id: CCO:B0015701 name: Q8N6B5_HUMAN def: "Forkhead/winged helix transcription factor" [UniProtKB:Q8N6B5] synonym: "Forkhead box P2, isoform CRA_d" EXACT [UniProtKB:Q8N6B5] xref: EMBL:AAM60769.1 xref: EMBL:EAW83482.1 xref: UniProtKB:Q8N6B5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011396 ! FOXP2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015705 name: Q8NAN6_HUMAN def: "cDNA FLJ35064 fis, clone PEBLM1000147, moderately similar to Glutamine (Q)-rich factor 1, QRF-1" [UniProtKB:Q8NAN6] xref: EMBL:BAC03875.1 xref: UniProtKB:Q8NAN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015706 name: Q0PRL4_HUMAN def: "Forkhead box P2 variant 3" [UniProtKB:Q0PRL4] xref: EMBL:ABG77460.1 xref: UniProtKB:Q0PRL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015709 name: Q8N2P0_HUMAN def: "cDNA FLJ90088 fis, clone HEMBA1005246" [UniProtKB:Q8N2P0] xref: EMBL:BAC11065.1 xref: UniProtKB:Q8N2P0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015710 name: Q7Z7F8_HUMAN def: "Forkhead box P4" [UniProtKB:Q7Z7F8] synonym: "Forkhead box P4, isoform CRA_c" EXACT [UniProtKB:Q7Z7F8] xref: EMBL:AAH52803.1 xref: EMBL:CAH72542.1 xref: EMBL:EAX04049.1 xref: UniProtKB:Q7Z7F8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011397 ! FOXP4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015712 name: FOXP1_HUMAN def: "Forkhead box protein P1" [UniProtKB:Q9H334] xref: EMBL:AAF36135.1 xref: EMBL:AAG47632.1 xref: EMBL:AAG47633.1 xref: EMBL:AAG47634.1 xref: EMBL:AAK69408.1 xref: EMBL:ABI33105.1 xref: EMBL:BAB55005.1 xref: UniProtKB:A3QVP8 xref: UniProtKB:Q9H332 xref: UniProtKB:Q9H333 xref: UniProtKB:Q9H334 xref: UniProtKB:Q9P0R1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011395 ! FOXP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015988 ! foxp1-nfatc2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066274 ! FOXP1_HUMAN-Phosphoserine440 [Term] id: CCO:B0015713 name: FOXP4_HUMAN def: "Forkhead box protein P4" [UniProtKB:Q8IVH2] synonym: "Fork head-related protein-like A" EXACT [UniProtKB:Q8IVH2] xref: EMBL:AAH13030.2 xref: EMBL:BAC53809.1 xref: UniProtKB:Q8IVH2 xref: UniProtKB:Q96E19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011397 ! FOXP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039437 ! FOXP4_HUMAN-Phosphoserine360 [Term] id: CCO:B0015715 name: Q96AP5_HUMAN def: "FOXP4 protein" [UniProtKB:Q96AP5] xref: EMBL:AAH16874.1 xref: UniProtKB:Q96AP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011397 ! FOXP4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015717 name: FOXP2_HUMAN def: "Forkhead box protein P2" [UniProtKB:O15409] synonym: "CAG repeat protein 44" EXACT [UniProtKB:O15409] synonym: "Trinucleotide repeat-containing gene 10 protein" EXACT [UniProtKB:O15409] xref: EMBL:AAB91439.1 xref: EMBL:AAL10762.1 xref: EMBL:AAM13672.1 xref: EMBL:AAM60762.1 xref: EMBL:AAM60763.1 xref: EMBL:AAM60764.1 xref: EMBL:AAM60765.1 xref: EMBL:AAM60766.1 xref: EMBL:AAM60767.1 xref: EMBL:AAN03389.1 xref: EMBL:AAN03390.1 xref: EMBL:AAN03391.1 xref: EMBL:AAN03392.1 xref: EMBL:AAN03393.1 xref: EMBL:AAN03394.1 xref: EMBL:AAN03395.1 xref: EMBL:AAN03396.1 xref: EMBL:AAN03397.1 xref: EMBL:AAN03398.1 xref: EMBL:AAN03399.1 xref: EMBL:AAN03400.1 xref: EMBL:AAN03401.1 xref: EMBL:AAN03402.1 xref: EMBL:AAN03403.1 xref: EMBL:AAN03404.1 xref: EMBL:AAN03405.1 xref: EMBL:AAN03406.1 xref: EMBL:AAN03407.1 xref: EMBL:AAN03408.1 xref: EMBL:AAN60016.1 xref: EMBL:AAS07399.1 xref: EMBL:AAS07502.1 xref: EMBL:BAD18444.1 xref: UniProtKB:O15409 xref: UniProtKB:Q6ZND1 xref: UniProtKB:Q75MJ3 xref: UniProtKB:Q8IZE0 xref: UniProtKB:Q8N0W2 xref: UniProtKB:Q8N6B7 xref: UniProtKB:Q8N6B8 xref: UniProtKB:Q8NFQ1 xref: UniProtKB:Q8NFQ2 xref: UniProtKB:Q8NFQ3 xref: UniProtKB:Q8NFQ4 xref: UniProtKB:Q8TD74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011396 ! FOXP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015987 ! foxp2-nfatc2-1 physical interaction relationship: participates_in CCO:I0018384 ! foxp2-nfatc2 direct interaction relationship: participates_in CCO:I0018878 ! foxp2-nfatc2-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015718 name: Q68DX8_HUMAN def: "Putative uncharacterized protein DKFZp686H1726" [UniProtKB:Q68DX8] xref: EMBL:CAH18092.1 xref: UniProtKB:Q68DX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011940 ! DKFZp686H1726_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015719 name: Q8IW55_HUMAN def: "Forkhead box P4" [UniProtKB:Q8IW55] synonym: "Forkhead box P4, isoform CRA_a" EXACT [UniProtKB:Q8IW55] xref: EMBL:AAH40962.1 xref: EMBL:CAH72541.1 xref: EMBL:EAX04047.1 xref: UniProtKB:Q8IW55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011397 ! FOXP4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015721 name: A3KMG1_HUMAN def: "FOXP1 protein" [UniProtKB:A3KMG1] xref: EMBL:AAI31721.1 xref: UniProtKB:A3KMG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011395 ! FOXP1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015778 name: PILRB_HUMAN def: "Paired immunoglobulin-like type 2 receptor beta precursor" [UniProtKB:Q9UKJ0] synonym: "Activating receptor PILR-beta" EXACT [UniProtKB:Q9UKJ0] synonym: "Cell surface receptor FDFACT" EXACT [UniProtKB:Q9UKJ0] xref: EMBL:AAD52965.1 xref: EMBL:AAG17224.1 xref: EMBL:AAH50547.1 xref: EMBL:CAC19193.1 xref: EMBL:CAC19194.1 xref: EMBL:CAH10711.1 xref: EMBL:CAH10714.1 xref: UniProtKB:Q69YF9 xref: UniProtKB:Q9HBS0 xref: UniProtKB:Q9UKJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007975 ! PILRB_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018453 ! bat5-q9ukj0 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000713 ! activation of transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:B0015779 name: PILRA_HUMAN def: "Paired immunoglobulin-like type 2 receptor alpha precursor" [UniProtKB:Q9UKJ1] synonym: "Cell surface receptor FDF03" EXACT [UniProtKB:Q9UKJ1] synonym: "Inhibitory receptor PILR-alpha" EXACT [UniProtKB:Q9UKJ1] xref: EMBL:AAD52964.1 xref: EMBL:AAH17812.1 xref: EMBL:CAC01613.1 xref: EMBL:CAC01614.1 xref: EMBL:CAC01615.1 xref: UniProtKB:Q8NHI1 xref: UniProtKB:Q9UKJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007974 ! PILRA_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015978 ! ptpn6-pilra-1 physical interaction relationship: participates_in CCO:I0017930 ! ptpn6-pilra-2 physical interaction relationship: participates_in CCO:I0017931 ! ptpn6-pilra-3 physical interaction relationship: participates_in CCO:I0017932 ! ptpn6-pilra-4b physical interaction relationship: participates_in CCO:I0018551 ! pilra-ptpn6-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0015783 name: Q5T188_HUMAN def: "SHC (Src homology 2 domain containing) transforming protein 1" [UniProtKB:Q5T188] xref: EMBL:CAI13246.1 xref: UniProtKB:Q5T188 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005610 ! SHC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0015787 name: Q5T182_HUMAN def: "SHC (Src homology 2 domain containing) transforming protein 1" [UniProtKB:Q5T182] xref: EMBL:CAI13252.1 xref: UniProtKB:Q5T182 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005610 ! SHC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0015789 name: Q5T187_HUMAN def: "SHC (Src homology 2 domain containing) transforming protein 1" [UniProtKB:Q5T187] xref: EMBL:CAI13247.1 xref: UniProtKB:Q5T187 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005610 ! SHC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0015792 name: Q5T181_HUMAN def: "SHC (Src homology 2 domain containing) transforming protein 1" [UniProtKB:Q5T181] xref: EMBL:CAI13253.1 xref: UniProtKB:Q5T181 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005610 ! SHC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0015822 name: ANXA5_HUMAN def: "Annexin A5" [UniProtKB:P08758] synonym: "Anchorin CII" EXACT [UniProtKB:P08758] synonym: "Annexin V" EXACT [UniProtKB:P08758] synonym: "Annexin-5" EXACT [UniProtKB:P08758] synonym: "Calphobindin I" EXACT [UniProtKB:P08758] synonym: "CBP-I" EXACT [UniProtKB:P08758] synonym: "Endonexin II" EXACT [UniProtKB:P08758] synonym: "Lipocortin V" EXACT [UniProtKB:P08758] synonym: "PAP-I" EXACT [UniProtKB:P08758] synonym: "Placental anticoagulant protein 4" EXACT [UniProtKB:P08758] synonym: "Placental anticoagulant protein I" EXACT [UniProtKB:P08758] synonym: "PP4" EXACT [UniProtKB:P08758] synonym: "Thromboplastin inhibitor" EXACT [UniProtKB:P08758] synonym: "VAC-alpha" EXACT [UniProtKB:P08758] synonym: "Vascular anticoagulant-alpha" EXACT [UniProtKB:P08758] xref: EMBL:AAA35570.1 xref: EMBL:AAA36166.1 xref: EMBL:AAA52386.1 xref: EMBL:AAB40047.1 xref: EMBL:AAB59545.1 xref: EMBL:AAB60648.1 xref: EMBL:AAH01429.1 xref: EMBL:AAH04993.1 xref: EMBL:AAH12804.1 xref: EMBL:AAH12822.1 xref: EMBL:AAH18671.1 xref: EMBL:BAA00122.1 xref: EMBL:CAA30985.1 xref: EMBL:CAG38759.1 xref: UniProtKB:P08758 xref: UniProtKB:Q6FI16 xref: UniProtKB:Q8WV69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007258 ! ANXA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020225 ! anxa5-fdft1 physical interaction relationship: participates_in CCO:I0020549 ! eif4g1-anxa5 physical interaction relationship: participates_in CCO:I0020676 ! supt4h1-anxa5 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0034555 ! ANXA5_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0034556 ! ANXA5_HUMAN-N6-acetyllysine101 relationship: transforms_into CCO:B0065655 ! ANXA5_HUMAN-Phosphotyrosine94 [Term] id: CCO:B0015830 name: ANXA9_HUMAN def: "Annexin A9" [UniProtKB:O76027] synonym: "Annexin XXXI" EXACT [UniProtKB:O76027] synonym: "Annexin-31" EXACT [UniProtKB:O76027] synonym: "Annexin-9" EXACT [UniProtKB:O76027] synonym: "Pemphaxin" EXACT [UniProtKB:O76027] xref: EMBL:AAG16780.1 xref: EMBL:AAH05830.2 xref: EMBL:CAA08933.1 xref: EMBL:CAG38720.1 xref: EMBL:CAI13335.1 xref: UniProtKB:O76027 xref: UniProtKB:Q5SZF1 xref: UniProtKB:Q6FI55 xref: UniProtKB:Q9BS00 xref: UniProtKB:Q9HBJ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007261 ! ANXA9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020554 ! kiaa1626-anxa9 physical interaction relationship: transforms_into CCO:B0034557 ! ANXA9_HUMAN-Phosphoserine2 [Term] id: CCO:B0015859 name: ANXA4_HUMAN def: "Annexin A4" [UniProtKB:P09525] synonym: "35-beta calcimedin" EXACT [UniProtKB:P09525] synonym: "Annexin IV" EXACT [UniProtKB:P09525] synonym: "Annexin-4" EXACT [UniProtKB:P09525] synonym: "Carbohydrate-binding protein p33/p41" EXACT [UniProtKB:P09525] synonym: "Chromobindin-4" EXACT [UniProtKB:P09525] synonym: "Endonexin I" EXACT [UniProtKB:P09525] synonym: "Lipocortin IV" EXACT [UniProtKB:P09525] synonym: "P32.5" EXACT [UniProtKB:P09525] synonym: "PAP-II" EXACT [UniProtKB:P09525] synonym: "Placental anticoagulant protein II" EXACT [UniProtKB:P09525] synonym: "PP4-X" EXACT [UniProtKB:P09525] synonym: "Protein II" EXACT [UniProtKB:P09525] xref: EMBL:AAA51740.1 xref: EMBL:AAC41689.1 xref: EMBL:AAH00182.1 xref: EMBL:AAH11659.1 xref: EMBL:BAA11227.1 xref: UniProtKB:P09525 xref: UniProtKB:Q96F33 xref: UniProtKB:Q9BWK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007257 ! ANXA4_human relationship: has_function CCO:F0001215 ! phospholipase inhibitor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0015866 name: TPIS_HUMAN def: "Triosephosphate isomerase" [UniProtKB:P60174] synonym: "EC 5.3.1.1" EXACT [UniProtKB:P60174] synonym: "TIM" EXACT [UniProtKB:P60174] synonym: "Triose-phosphate isomerase" EXACT [UniProtKB:P60174] xref: EMBL:AAB51316.1 xref: EMBL:AAB59511.1 xref: EMBL:AAH07086.1 xref: EMBL:AAH07812.1 xref: EMBL:AAH09329.1 xref: EMBL:AAH11611.1 xref: EMBL:AAH15100.1 xref: EMBL:AAH17165.1 xref: EMBL:AAH17917.1 xref: EMBL:AAH70129.1 xref: EMBL:AAN86636.1 xref: EMBL:CAA49379.1 xref: UniProtKB:P00938 xref: UniProtKB:P60174 xref: UniProtKB:Q6IS07 xref: UniProtKB:Q8WWD0 xref: UniProtKB:Q96AG5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008320 ! TPI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020206 ! tpi1-setdb1 physical interaction relationship: participates_in CCO:I0020680 ! tpi1-ccl11 physical interaction relationship: transforms_into CCO:B0035812 ! TPIS_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0035813 ! TPIS_HUMAN-N6-acetyllysine188 [Term] id: CCO:B0015901 name: RS6_HUMAN def: "40S ribosomal protein S6" [UniProtKB:P62753] synonym: "Phosphoprotein NP33" EXACT [UniProtKB:P62753] xref: EMBL:AAA60287.1 xref: EMBL:AAA60288.1 xref: EMBL:AAA60289.1 xref: EMBL:AAH00524.1 xref: EMBL:AAH09427.2 xref: EMBL:AAH27620.1 xref: EMBL:AAH71907.1 xref: EMBL:AAH71908.1 xref: EMBL:AAH94826.1 xref: EMBL:BAB93455.1 xref: EMBL:CAA47719.1 xref: UniProtKB:P08227 xref: UniProtKB:P10660 xref: UniProtKB:P62753 xref: UniProtKB:Q4VBY7 xref: UniProtKB:Q8N6Z7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022616 ! RPS6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0016615 ! map3k1-rps6 physical interaction relationship: transforms_into CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0070215 ! RS6_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0070216 ! RS6_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0070217 ! RS6_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0070218 ! RS6_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0070219 ! RS6_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0070220 ! RS6_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0070221 ! RS6_HUMAN-Phosphoserine247 [Term] id: CCO:B0015956 name: IFNK_HUMAN def: "Interferon kappa precursor" [UniProtKB:Q9P0W0] synonym: "IFN-kappa" EXACT [UniProtKB:Q9P0W0] xref: EMBL:AAF67468.1 xref: EMBL:AAK01623.1 xref: EMBL:AAK63835.1 xref: EMBL:AAQ89214.1 xref: EMBL:CAI13042.1 xref: UniProtKB:Q5T166 xref: UniProtKB:Q9P0W0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007663 ! IFNK_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001434 ! interferon-alpha/beta receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0015966 name: IFNB_HUMAN def: "Interferon beta precursor" [UniProtKB:P01574] synonym: "Fibroblast interferon" EXACT [UniProtKB:P01574] synonym: "IFN-beta" EXACT [UniProtKB:P01574] xref: EMBL:AAA36040.1 xref: EMBL:AAH69314.1 xref: EMBL:CAA23795.1 xref: EMBL:CAA23796.1 xref: EMBL:CAA23807.1 xref: EMBL:CAA23808.1 xref: UniProtKB:P01574 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011485 ! IFNB1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001434 ! interferon-alpha/beta receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002040 ! B cell proliferation relationship: transforms_into CCO:B0039469 ! IFNB_HUMAN-Phosphoserine140 [Term] id: CCO:B0015973 name: IFNA2_HUMAN def: "Interferon alpha-2 precursor" [UniProtKB:P01563] synonym: "Interferon alpha-A" EXACT [UniProtKB:P01563] synonym: "LeIF A" EXACT [UniProtKB:P01563] xref: EMBL:AAA52715.1 xref: EMBL:AAA59181.1 xref: EMBL:AAB59402.1 xref: EMBL:CAA00410.1 xref: EMBL:CAA23805.1 xref: EMBL:CAA23809.1 xref: EMBL:CAA23810.1 xref: EMBL:CAA72532.1 xref: UniProtKB:P01563 xref: UniProtKB:P01564 xref: UniProtKB:Q14606 xref: UniProtKB:Q96KI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007655 ! IFNA2_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001434 ! interferon-alpha/beta receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0015979 name: MNDA_HUMAN def: "Myeloid cell nuclear differentiation antigen" [UniProtKB:P41218] xref: EMBL:AAA69696.1 xref: EMBL:AAH32319.1 xref: UniProtKB:P41218 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018642 ! MNDA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0015997 name: KCRB_HUMAN def: "Creatine kinase B-type" [UniProtKB:P12277] synonym: "B-CK" EXACT [UniProtKB:P12277] synonym: "Creatine kinase B chain" EXACT [UniProtKB:P12277] synonym: "EC 2.7.3.2" EXACT [UniProtKB:P12277] xref: EMBL:AAA52024.1 xref: EMBL:AAA76850.1 xref: EMBL:AAA76851.1 xref: EMBL:AAA76852.1 xref: EMBL:AAC31758.1 xref: EMBL:AAH01190.1 xref: EMBL:AAH04914.1 xref: EMBL:AAH08323.1 xref: EMBL:AAH10002.1 xref: EMBL:AAH19259.1 xref: EMBL:AAH19281.1 xref: EMBL:ABC67465.1 xref: EMBL:CAA33389.1 xref: UniProtKB:P12277 xref: UniProtKB:Q2LE07 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007740 ! CKB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015280 ! asb9-ckb physical interaction relationship: transforms_into CCO:B0035012 ! KCRB_HUMAN-Phosphotyrosine39 relationship: transforms_into CCO:B0035013 ! KCRB_HUMAN-Phosphotyrosine125 relationship: transforms_into CCO:B0035014 ! KCRB_HUMAN-Phosphoserine164 [Term] id: CCO:B0016000 name: MTERF_HUMAN def: "Transcription termination factor, mitochondrial precursor" [UniProtKB:Q99551] synonym: "Mitochondrial transcription termination factor 1" EXACT [UniProtKB:Q99551] synonym: "mTERF" EXACT [UniProtKB:Q99551] xref: EMBL:AAB83941.1 xref: EMBL:AAH00965.1 xref: EMBL:AAI08649.1 xref: EMBL:AAI30390.1 xref: EMBL:AAI30392.1 xref: EMBL:CAA70830.1 xref: UniProtKB:Q32NF8 xref: UniProtKB:Q99551 xref: UniProtKB:Q9BVR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018675 ! MTERF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000302 ! transcription termination factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016003 name: MTER3_HUMAN def: "mTERF domain-containing protein 3, mitochondrial precursor" [UniProtKB:Q49AM1] synonym: "Mitochondrial transcription termination factor-like protein" EXACT [UniProtKB:Q49AM1] synonym: "mTERFL" EXACT [UniProtKB:Q49AM1] xref: EMBL:AAG22860.1 xref: EMBL:AAH25984.1 xref: EMBL:AAH36066.1 xref: EMBL:BAB14834.1 xref: EMBL:BAD96278.1 xref: EMBL:CAI46173.1 xref: UniProtKB:Q49AM1 xref: UniProtKB:Q53HM2 xref: UniProtKB:Q9H4L6 xref: UniProtKB:Q9H7Y9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018674 ! MTERFD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016028 name: HIRA_HUMAN def: "Protein HIRA" [UniProtKB:P54198] synonym: "TUP1-like enhancer of split protein 1" EXACT [UniProtKB:P54198] xref: EMBL:AAH32721.1 xref: EMBL:AAH39835.1 xref: EMBL:CAA53044.1 xref: EMBL:CAA54721.1 xref: EMBL:CAA57436.1 xref: EMBL:CAA61979.1 xref: EMBL:CAA62800.1 xref: EMBL:CAG30389.1 xref: UniProtKB:P54198 xref: UniProtKB:Q05BU9 xref: UniProtKB:Q8IXN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007624 ! HIRA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0034856 ! HIRA_HUMAN-Phosphothreonine555 relationship: transforms_into CCO:B0034857 ! HIRA_HUMAN-Phosphoserine687 relationship: transforms_into CCO:B0066806 ! HIRA_HUMAN-Phosphothreonine576 relationship: transforms_into CCO:B0066807 ! HIRA_HUMAN-Phosphoserine584 relationship: transforms_into CCO:B0066808 ! HIRA_HUMAN-Phosphothreonine586 relationship: transforms_into CCO:B0066809 ! HIRA_HUMAN-Phosphoserine610 relationship: transforms_into CCO:B0066810 ! HIRA_HUMAN-Phosphoserine611 relationship: transforms_into CCO:B0066811 ! HIRA_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0066812 ! HIRA_HUMAN-Phosphoserine614 [Term] id: CCO:B0016049 name: I2C2_HUMAN def: "Eukaryotic translation initiation factor 2C 2" [UniProtKB:Q9UKV8] synonym: "Argonaute-2" EXACT [UniProtKB:Q9UKV8] synonym: "eIF-2C 2" EXACT [UniProtKB:Q9UKV8] synonym: "eIF2C 2" EXACT [UniProtKB:Q9UKV8] synonym: "PAZ Piwi domain protein" EXACT [UniProtKB:Q9UKV8] synonym: "PPD" EXACT [UniProtKB:Q9UKV8] synonym: "Slicer protein" EXACT [UniProtKB:Q9UKV8] xref: EMBL:AAF13034.2 xref: EMBL:AAH07633.1 xref: EMBL:AAH18727.2 xref: EMBL:AAL76093.1 xref: EMBL:AAP35893.1 xref: UniProtKB:Q8TCZ5 xref: UniProtKB:Q8WV58 xref: UniProtKB:Q96ID1 xref: UniProtKB:Q9UKV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007642 ! EIF2C2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017368 ! eif2c2-dicer1-2 physical interaction relationship: participates_in CCO:I0017370 ! eif2c2-dicer1-3 physical interaction relationship: participates_in CCO:I0018042 ! dicer1-eif2c2-3 physical interaction relationship: participates_in CCO:I0018496 ! dicer1-eif2c2-2 physical interaction relationship: participates_in CCO:I0018499 ! eif2c2-dicer1-1 physical interaction relationship: participates_in CCO:I0019362 ! dicer1-eif2c2-4 physical interaction relationship: participates_in CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:B0016054 name: I2C3_HUMAN def: "Eukaryotic translation initiation factor 2C 3" [UniProtKB:Q9H9G7] synonym: "Argonaute-3" EXACT [UniProtKB:Q9H9G7] synonym: "eIF-2C 3" EXACT [UniProtKB:Q9H9G7] synonym: "eIF2C 3" EXACT [UniProtKB:Q9H9G7] xref: EMBL:BAB14262.1 xref: EMBL:CAI22268.1 xref: EMBL:CAI22802.1 xref: UniProtKB:Q5TA55 xref: UniProtKB:Q9H1U6 xref: UniProtKB:Q9H9G7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007643 ! EIF2C3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:B0016055 name: I2C4_HUMAN def: "Eukaryotic translation initiation factor 2C 4" [UniProtKB:Q9HCK5] synonym: "Argonaute-4" EXACT [UniProtKB:Q9HCK5] synonym: "eIF-2C 4" EXACT [UniProtKB:Q9HCK5] synonym: "eIF2C 4" EXACT [UniProtKB:Q9HCK5] xref: EMBL:BAB13393.1 xref: UniProtKB:Q9HCK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007644 ! EIF2C4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001363 ! gene silencing by RNA relationship: transforms_into CCO:B0034865 ! I2C4_HUMAN-Phosphoserine798 [Term] id: CCO:B0016057 name: I2C1_HUMAN def: "Eukaryotic translation initiation factor 2C 1" [UniProtKB:Q9UL18] synonym: "Argonaute-1" EXACT [UniProtKB:Q9UL18] synonym: "eIF-2C 1" EXACT [UniProtKB:Q9UL18] synonym: "eIF2C 1" EXACT [UniProtKB:Q9UL18] synonym: "Putative RNA-binding protein Q99" EXACT [UniProtKB:Q9UL18] xref: EMBL:AAF00068.1 xref: EMBL:AAH63275.1 xref: EMBL:CAI22804.1 xref: UniProtKB:Q5TA57 xref: UniProtKB:Q6P4S0 xref: UniProtKB:Q9UL18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007641 ! EIF2C1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000416 ! eukaryotic translation initiation factor 2 complex relationship: participates_in CCO:I0017701 ! dicer1-eif2c1-2 physical interaction relationship: participates_in CCO:I0018795 ! eif2c1-dicer1-1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: participates_in CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:B0016067 name: Q4G0Q6_HUMAN def: "MGC72080 protein" [UniProtKB:Q4G0Q6] xref: EMBL:AAH42035.1 xref: UniProtKB:Q4G0Q6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021120 ! MGC72080_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0016073 name: Q6P5R4_HUMAN def: "MGC72080 protein" [UniProtKB:Q6P5R4] xref: EMBL:AAH29615.1 xref: EMBL:AAH62733.1 xref: UniProtKB:Q6P5R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021120 ! MGC72080_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0016149 name: PRP19_HUMAN def: "Pre-mRNA-processing factor 19" [UniProtKB:Q9UMS4] synonym: "hPso4" EXACT [UniProtKB:Q9UMS4] synonym: "Nuclear matrix protein 200" EXACT [UniProtKB:Q9UMS4] synonym: "PRP19/PSO4 homolog" EXACT [UniProtKB:Q9UMS4] synonym: "Senescence evasion factor" EXACT [UniProtKB:Q9UMS4] xref: EMBL:AAH08719.1 xref: EMBL:AAH18665.1 xref: EMBL:AAH18698.1 xref: EMBL:CAB51857.1 xref: UniProtKB:Q9UMS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019519 ! PRPF19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0015819 ! exoc7-prp19 physical interaction relationship: participates_in CCO:P0000477 ! inner cell mass cell proliferation relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation relationship: participates_in CCO:P0002883 ! positive regulation of astrocyte differentiation relationship: transforms_into CCO:B0069543 ! PRP19_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0069544 ! PRP19_HUMAN-Phosphothreonine310 relationship: transforms_into CCO:B0069545 ! PRP19_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0069546 ! PRP19_HUMAN-Phosphotyrosine329 relationship: transforms_into CCO:B0069547 ! PRP19_HUMAN-Phosphothreonine342 [Term] id: CCO:B0016186 name: IF4E_HUMAN def: "Eukaryotic translation initiation factor 4E" [UniProtKB:P06730] synonym: "eIF-4E" EXACT [UniProtKB:P06730] synonym: "eIF-4F 25 kDa subunit" EXACT [UniProtKB:P06730] synonym: "eIF4E" EXACT [UniProtKB:P06730] synonym: "mRNA cap-binding protein" EXACT [UniProtKB:P06730] xref: EMBL:AAC13647.1 xref: EMBL:AAH12611.1 xref: EMBL:AAH35166.1 xref: EMBL:AAH43226.1 xref: UniProtKB:P06730 xref: UniProtKB:Q96E95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011482 ! EIF4E_human relationship: has_function CCO:F0000071 ! RNA cap binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: participates_in CCO:I0015830 ! eif4e-eif4ebp1 physical interaction relationship: participates_in CCO:I0015968 ! gemin5-eif4e-1 colocalization relationship: participates_in CCO:I0016131 ! eif4e-mnk1 physical interaction relationship: participates_in CCO:I0016132 ! mnk1-eif4e physical interaction relationship: participates_in CCO:I0016153 ! eif4e-4ebp1-1 direct interaction relationship: participates_in CCO:I0016155 ! eif4e-4ebp2-1 direct interaction relationship: participates_in CCO:I0016156 ! eif4e-4ebp3-1 direct interaction relationship: participates_in CCO:I0016318 ! gemin5-eif4e direct interaction relationship: participates_in CCO:I0017347 ! eif4e-emx2-1 physical interaction relationship: participates_in CCO:I0017348 ! emx2-eif4e-1 physical interaction relationship: participates_in CCO:I0017349 ! eif4e-emx2-2 physical interaction relationship: participates_in CCO:I0017647 ! eif4e-4ebp1 physical interaction relationship: participates_in CCO:I0017976 ! eif4e-importinalpha- physical interaction relationship: participates_in CCO:I0018275 ! 4et-eif4e physical interaction relationship: participates_in CCO:I0018482 ! ncbp2-eif4gi physical interaction relationship: participates_in CCO:I0019215 ! 4ebp1-eif4e physical interaction relationship: participates_in CCO:I0019339 ! eif4e-4et physical interaction relationship: participates_in CCO:I0019344 ! emx2-eif4e-2 physical interaction relationship: participates_in CCO:I0019445 ! eif4e-gemin5 direct interaction relationship: participates_in CCO:I0019448 ! eif4e-eif4g1-1 direct interaction relationship: participates_in CCO:I0019454 ! eif4e-4ebp3-2 direct interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0039462 ! IF4E_HUMAN-Phosphoserine209 [Term] id: CCO:B0016191 name: I4E1B_HUMAN def: "Eukaryotic translation initiation factor 4E type 1B" [UniProtKB:A6NMX2] xref: UniProtKB:A6NMX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022326 ! EIF4E1B_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0016195 name: KHDR2_HUMAN def: "KH domain-containing, RNA-binding, signal transduction-associated protein 2" [UniProtKB:Q5VWX1] synonym: "hSLM-1" EXACT [UniProtKB:Q5VWX1] synonym: "Sam68-like mammalian protein 1" EXACT [UniProtKB:Q5VWX1] synonym: "SLM-1" EXACT [UniProtKB:Q5VWX1] xref: EMBL:AAH34043.1 xref: EMBL:AAL77219.1 xref: EMBL:CAH70882.1 xref: EMBL:CAI14907.1 xref: EMBL:CAI15262.1 xref: EMBL:CAI19748.1 xref: EMBL:CAI19918.1 xref: EMBL:CAI21649.1 xref: EMBL:EAW88490.1 xref: UniProtKB:Q5VWX1 xref: UniProtKB:Q8N4I4 xref: UniProtKB:Q8TCZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007745 ! KHDRBS2_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016220 name: DNJB1_HUMAN def: "DnaJ homolog subfamily B member 1" [UniProtKB:P25685] synonym: "DnaJ protein homolog 1" EXACT [UniProtKB:P25685] synonym: "HDJ-1" EXACT [UniProtKB:P25685] synonym: "Heat shock 40 kDa protein 1" EXACT [UniProtKB:P25685] synonym: "Heat shock protein 40" EXACT [UniProtKB:P25685] synonym: "HSP40" EXACT [UniProtKB:P25685] xref: EMBL:AAH02352.1 xref: EMBL:AAH19827.1 xref: EMBL:BAA08495.1 xref: EMBL:BAA12819.1 xref: EMBL:CAA44287.1 xref: UniProtKB:P25685 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007464 ! DNAJB1_human relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016698 ! map3k3-dnajb1 physical interaction [Term] id: CCO:B0016224 name: DNJB4_HUMAN def: "DnaJ homolog subfamily B member 4" [UniProtKB:Q9UDY4] synonym: "Heat shock 40 kDa protein 1 homolog" EXACT [UniProtKB:Q9UDY4] synonym: "Heat shock protein 40 homolog" EXACT [UniProtKB:Q9UDY4] synonym: "HSP40 homolog" EXACT [UniProtKB:Q9UDY4] synonym: "Human liver DnaJ-like protein" EXACT [UniProtKB:Q9UDY4] xref: EMBL:AAB07346.1 xref: EMBL:AAC14483.2 xref: EMBL:AAH34721.1 xref: UniProtKB:Q13431 xref: UniProtKB:Q9UDY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007465 ! DNAJB4_human relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016670 ! map3k3-dnajb4 physical interaction relationship: transforms_into CCO:B0034710 ! DNJB4_HUMAN-Phosphotyrosine172 relationship: transforms_into CCO:B0065954 ! DNJB4_HUMAN-Phosphoserine122 [Term] id: CCO:B0016257 name: Q9BR65_HUMAN def: "V-Ha-ras Harvey rat sarcoma viral oncogene homolog" [UniProtKB:Q9BR65] synonym: "p19 H-RasIDX protein" EXACT [UniProtKB:Q9BR65] synonym: "V-Ha-ras Harvey rat sarcoma viral oncogene homolog, isoform CRA_b" EXACT [UniProtKB:Q9BR65] xref: EMBL:AAH06499.1 xref: EMBL:ABI97389.1 xref: EMBL:CAD24594.1 xref: EMBL:EAX02338.1 xref: UniProtKB:Q9BR65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005433 ! HRAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0016299 name: PP2BC_HUMAN def: "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform" [UniProtKB:P48454] synonym: "Calcineurin, testis-specific catalytic subunit" EXACT [UniProtKB:P48454] synonym: "Calmodulin-dependent calcineurin A subunit gamma isoform" EXACT [UniProtKB:P48454] synonym: "CAM-PRP catalytic subunit" EXACT [UniProtKB:P48454] synonym: "EC 3.1.3.16" EXACT [UniProtKB:P48454] xref: EMBL:AAB23769.1 xref: EMBL:AAG02563.1 xref: EMBL:EAW63679.1 xref: UniProtKB:P48454 xref: UniProtKB:Q9H4M5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019477 ! PPP3CC_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products [Term] id: CCO:B0016306 name: PP2BA_HUMAN def: "Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform" [UniProtKB:Q08209] synonym: "Calmodulin-dependent calcineurin A subunit alpha isoform" EXACT [UniProtKB:Q08209] synonym: "CAM-PRP catalytic subunit" EXACT [UniProtKB:Q08209] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q08209] xref: EMBL:AAA02631.1 xref: EMBL:AAH25714.1 xref: EMBL:CAB89253.1 xref: UniProtKB:Q08209 xref: UniProtKB:Q8TAW9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022522 ! PPP3CA_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000504 ! calcineurin complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0069456 ! PP2BA_HUMAN-Phosphoserine469 [Term] id: CCO:B0016326 name: AAKG2_HUMAN def: "5'-AMP-activated protein kinase subunit gamma-2" [UniProtKB:Q9UGJ0] synonym: "AMPK gamma-2 chain" EXACT [UniProtKB:Q9UGJ0] synonym: "AMPK gamma2" EXACT [UniProtKB:Q9UGJ0] synonym: "H91620p" EXACT [UniProtKB:Q9UGJ0] xref: EMBL:AAF03528.2 xref: EMBL:AAH20540.2 xref: EMBL:AAH68598.1 xref: EMBL:AAK00413.1 xref: EMBL:AAP35791.1 xref: EMBL:AAS02032.1 xref: EMBL:BAA84695.1 xref: EMBL:BAA91962.1 xref: EMBL:CAB65116.1 xref: UniProtKB:Q53Y07 xref: UniProtKB:Q6NUI0 xref: UniProtKB:Q75MP4 xref: UniProtKB:Q9NUZ9 xref: UniProtKB:Q9UDN8 xref: UniProtKB:Q9UGJ0 xref: UniProtKB:Q9ULX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016868 ! PRKAG2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation relationship: transforms_into CCO:B0065242 ! AAKG2_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0065243 ! AAKG2_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0065244 ! AAKG2_HUMAN-Phosphoserine73 relationship: transforms_into CCO:B0065245 ! AAKG2_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0065246 ! AAKG2_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0065247 ! AAKG2_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0065248 ! AAKG2_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0065249 ! AAKG2_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0065250 ! AAKG2_HUMAN-Phosphothreonine167 relationship: transforms_into CCO:B0065251 ! AAKG2_HUMAN-Phosphoserine196 [Term] id: CCO:B0016329 name: AAKG1_HUMAN def: "5'-AMP-activated protein kinase subunit gamma-1" [UniProtKB:P54619] synonym: "AMPK gamma-1 chain" EXACT [UniProtKB:P54619] synonym: "AMPKg" EXACT [UniProtKB:P54619] xref: EMBL:AAC50495.1 xref: EMBL:AAH00358.1 xref: EMBL:AAP36009.1 xref: UniProtKB:P54619 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016867 ! PRKAG1_human relationship: has_function CCO:F0001058 ! cAMP-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016331 name: AAKG3_HUMAN def: "5'-AMP-activated protein kinase subunit gamma-3" [UniProtKB:Q9UGI9] synonym: "AMPK gamma-3 chain" EXACT [UniProtKB:Q9UGI9] synonym: "AMPK gamma3" EXACT [UniProtKB:Q9UGI9] xref: EMBL:AAF73987.1 xref: EMBL:AAH98102.1 xref: EMBL:AAH98255.1 xref: EMBL:AAH98277.1 xref: EMBL:AAH98306.1 xref: EMBL:CAB65117.1 xref: UniProtKB:Q4QQG8 xref: UniProtKB:Q4V779 xref: UniProtKB:Q9NRL1 xref: UniProtKB:Q9UGI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016869 ! PRKAG3_human relationship: has_function CCO:F0001049 ! AMP-activated protein kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0016344 name: IF4G3_HUMAN def: "Eukaryotic translation initiation factor 4 gamma 3" [UniProtKB:O43432] synonym: "eIF-4-gamma 3" EXACT [UniProtKB:O43432] synonym: "eIF-4-gamma II" EXACT [UniProtKB:O43432] synonym: "eIF-4G 3" EXACT [UniProtKB:O43432] synonym: "eIF4G 3" EXACT [UniProtKB:O43432] synonym: "eIF4GII" EXACT [UniProtKB:O43432] xref: EMBL:AAC02903.2 xref: EMBL:AAH30578.1 xref: EMBL:CAA84397.1 xref: EMBL:CAI12155.1 xref: EMBL:CAI12534.1 xref: EMBL:CAI14553.1 xref: EMBL:EAW94956.1 xref: UniProtKB:O43432 xref: UniProtKB:Q15597 xref: UniProtKB:Q5SWC3 xref: UniProtKB:Q8NEN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018230 ! EIF4G3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018483 ! eif4g3-ncbp1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0067040 ! IF4G3_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0067041 ! IF4G3_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0067042 ! IF4G3_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0067043 ! IF4G3_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0067044 ! IF4G3_HUMAN-Phosphoserine1156 [Term] id: CCO:B0016356 name: Q6KH11_HUMAN def: "Ral guanine nucleotide dissociation stimulator A" [UniProtKB:Q6KH11] synonym: "Ral guanine nucleotide dissociation stimulator" EXACT [UniProtKB:Q6KH11] synonym: "Ral guanine nucleotide dissociation stimulator, isoform CRA_d" EXACT [UniProtKB:Q6KH11] xref: EMBL:AAQ13414.1 xref: EMBL:CAI13417.1 xref: EMBL:EAW88040.1 xref: UniProtKB:Q6KH11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004711 ! RALGDS_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0016357 name: Q6PCE1_HUMAN def: "RALGDS protein" [UniProtKB:Q6PCE1] synonym: "Ral guanine nucleotide dissociation stimulator" EXACT [UniProtKB:Q6PCE1] xref: EMBL:AAH59362.1 xref: EMBL:CAI13416.1 xref: UniProtKB:Q6PCE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004711 ! RALGDS_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0016358 name: Q495L7_HUMAN def: "RGL4 protein" [UniProtKB:Q495L7] xref: EMBL:AAI01110.1 xref: UniProtKB:Q495L7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019690 ! RGL4_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0016364 name: Q5T7U6_HUMAN def: "Ral guanine nucleotide dissociation stimulator" [UniProtKB:Q5T7U6] xref: EMBL:CAI13414.1 xref: UniProtKB:Q5T7U6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004711 ! RALGDS_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0016366 name: Q9P2N8_HUMAN xref: UniProtKB:Q9P2N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0016367 name: RGL3_HUMAN def: "Ral guanine nucleotide dissociation stimulator-like 3" [UniProtKB:Q3MIN7] synonym: "RalGDS-like 3" EXACT [UniProtKB:Q3MIN7] xref: EMBL:AAH14426.1 xref: EMBL:AAI01757.1 xref: EMBL:AAI11959.1 xref: UniProtKB:Q0P6G0 xref: UniProtKB:Q3MIN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019695 ! RGL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0069912 ! RGL3_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0069913 ! RGL3_HUMAN-Phosphoserine508 relationship: transforms_into CCO:B0069914 ! RGL3_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0069915 ! RGL3_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0069916 ! RGL3_HUMAN-Phosphoserine573 [Term] id: CCO:B0016368 name: Q8TEP0_HUMAN def: "FLJ00153 protein" [UniProtKB:Q8TEP0] xref: EMBL:BAB84908.1 xref: UniProtKB:Q8TEP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021245 ! FLJ00153_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0016369 name: Q6ZSD5_HUMAN def: "cDNA FLJ45617 fis, clone BRTHA3026916, highly similar to Ral guanine nucleotide dissociation stimulator" [UniProtKB:Q6ZSD5] xref: EMBL:BAC87018.1 xref: UniProtKB:Q6ZSD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0016370 name: Q8TEK8_HUMAN def: "FLJ00186 protein" [UniProtKB:Q8TEK8] xref: EMBL:BAB84941.1 xref: UniProtKB:Q8TEK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008894 ! FLJ00186_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016435 name: IF1AY_HUMAN def: "Eukaryotic translation initiation factor 1A, Y-chromosomal" [UniProtKB:O14602] synonym: "eIF-1A Y isoform" EXACT [UniProtKB:O14602] synonym: "eIF-4C" EXACT [UniProtKB:O14602] xref: EMBL:AAC51834.1 xref: EMBL:AAH05248.1 xref: EMBL:AAP35865.1 xref: UniProtKB:O14602 xref: UniProtKB:Q9BS77 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022333 ! EIF1AY_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017975 ! eif1a-eif5b-2 direct interaction relationship: participates_in CCO:I0018055 ! eif1a-eif5b-1 direct interaction relationship: participates_in CCO:I0019031 ! atxn1-eif1ay physical interaction [Term] id: CCO:B0016462 name: Q9NYG7_HUMAN def: "Bax-sigma" [UniProtKB:Q9NYG7] synonym: "BCL2-associated X protein, isoform CRA_c" EXACT [UniProtKB:Q9NYG7] xref: EMBL:AAF71267.1 xref: EMBL:EAW52417.1 xref: UniProtKB:Q9NYG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004143 ! BAX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0016489 name: PA24B_HUMAN def: "Cytosolic phospholipase A2 beta" [UniProtKB:P0C869] synonym: "cPLA2-beta" EXACT [UniProtKB:P0C869] synonym: "EC 3.1.1.4" EXACT [UniProtKB:P0C869] synonym: "Phospholipase A2 group IVB" EXACT [UniProtKB:P0C869] xref: EMBL:AAC78836.1 xref: EMBL:AAD32135.1 xref: EMBL:BAD92387.1 xref: UniProtKB:O95712 xref: UniProtKB:P0C869 xref: UniProtKB:Q59GF9 xref: UniProtKB:Q8TB10 xref: UniProtKB:Q9UKV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019283 ! PLA2G4B_human relationship: has_function CCO:F0000999 ! phospholipase activity relationship: has_function CCO:F0001001 ! lysophospholipase activity relationship: has_function CCO:F0001002 ! phospholipase A2 activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006802 ! calcium-dependent phospholipase A2 activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0016505 name: KCC2D_HUMAN def: "Calcium/calmodulin-dependent protein kinase type II delta chain" [UniProtKB:Q13557] synonym: "CaM kinase II subunit delta" EXACT [UniProtKB:Q13557] synonym: "CaM-kinase II delta chain" EXACT [UniProtKB:Q13557] synonym: "CaMK-II subunit delta" EXACT [UniProtKB:Q13557] synonym: "EC 2.7.11.17" EXACT [UniProtKB:Q13557] xref: EMBL:AAB16866.1 xref: EMBL:AAD20442.1 xref: EMBL:AAH32784.1 xref: EMBL:AAX88806.1 xref: EMBL:BAD92525.1 xref: EMBL:CAB65123.1 xref: UniProtKB:Q13557 xref: UniProtKB:Q52PK4 xref: UniProtKB:Q59G21 xref: UniProtKB:Q8N553 xref: UniProtKB:Q9UGH6 xref: UniProtKB:Q9UQE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018384 ! CAMK2D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0067273 ! KCC2D_HUMAN-Phosphotyrosine231 relationship: transforms_into CCO:B0067274 ! KCC2D_HUMAN-Phosphothreonine287 relationship: transforms_into CCO:B0067275 ! KCC2D_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0067276 ! KCC2D_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0067277 ! KCC2D_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0067278 ! KCC2D_HUMAN-Phosphothreonine331 relationship: transforms_into CCO:B0067279 ! KCC2D_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0067280 ! KCC2D_HUMAN-Phosphothreonine337 [Term] id: CCO:B0016540 name: KCC4_HUMAN def: "Calcium/calmodulin-dependent protein kinase type IV" [UniProtKB:Q16566] synonym: "CAM kinase-GR" EXACT [UniProtKB:Q16566] synonym: "CaMK IV" EXACT [UniProtKB:Q16566] synonym: "EC 2.7.11.17" EXACT [UniProtKB:Q16566] xref: EMBL:AAA18251.1 xref: EMBL:AAA35639.1 xref: EMBL:AAH16695.2 xref: EMBL:AAH25687.1 xref: EMBL:BAA06403.1 xref: UniProtKB:Q16566 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007730 ! CAMK4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0034996 ! KCC4_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0034997 ! KCC4_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0034998 ! KCC4_HUMAN-Phosphothreonine200 relationship: transforms_into CCO:B0034999 ! KCC4_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0035000 ! KCC4_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0035001 ! KCC4_HUMAN-Phosphoserine360 [Term] id: CCO:B0016545 name: KCC2B_HUMAN def: "Calcium/calmodulin-dependent protein kinase type II beta chain" [UniProtKB:Q13554] synonym: "CaM kinase II subunit beta" EXACT [UniProtKB:Q13554] synonym: "CaM-kinase II beta chain" EXACT [UniProtKB:Q13554] synonym: "CaMK-II subunit beta" EXACT [UniProtKB:Q13554] synonym: "EC 2.7.11.17" EXACT [UniProtKB:Q13554] xref: EMBL:AAB16863.1 xref: EMBL:AAC99802.1 xref: EMBL:AAD03743.1 xref: EMBL:AAD03744.1 xref: EMBL:AAD42035.1 xref: EMBL:AAD42036.1 xref: EMBL:AAD42037.1 xref: EMBL:AAD42038.1 xref: EMBL:AAD42070.1 xref: EMBL:AAH19070.1 xref: EMBL:CAB65120.1 xref: EMBL:CAB65121.1 xref: EMBL:CAB65122.1 xref: UniProtKB:O95437 xref: UniProtKB:O95438 xref: UniProtKB:O95599 xref: UniProtKB:Q13554 xref: UniProtKB:Q9UGH7 xref: UniProtKB:Q9UGH8 xref: UniProtKB:Q9UGH9 xref: UniProtKB:Q9UNX0 xref: UniProtKB:Q9UNX7 xref: UniProtKB:Q9UP00 xref: UniProtKB:Q9Y5N4 xref: UniProtKB:Q9Y6F4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018383 ! CAMK2B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067268 ! KCC2B_HUMAN-Phosphotyrosine17 relationship: transforms_into CCO:B0067269 ! KCC2B_HUMAN-Phosphothreonine287 relationship: transforms_into CCO:B0067270 ! KCC2B_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0067271 ! KCC2B_HUMAN-Phosphoserine367 relationship: transforms_into CCO:B0067272 ! KCC2B_HUMAN-Phosphoserine397 [Term] id: CCO:B0016556 name: KCC1A_HUMAN def: "Calcium/calmodulin-dependent protein kinase type 1" [UniProtKB:Q14012] synonym: "CaM kinase I" EXACT [UniProtKB:Q14012] synonym: "CaM kinase I alpha" EXACT [UniProtKB:Q14012] synonym: "CaM-KI" EXACT [UniProtKB:Q14012] synonym: "CaMKI-alpha" EXACT [UniProtKB:Q14012] synonym: "EC 2.7.11.17" EXACT [UniProtKB:Q14012] xref: EMBL:AAA99458.1 xref: EMBL:AAI06755.1 xref: EMBL:AAI06756.1 xref: UniProtKB:Q14012 xref: UniProtKB:Q3KPF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007725 ! CAMK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0034986 ! KCC1A_HUMAN-Phosphothreonine177 [Term] id: CCO:B0016569 name: KCC2A_HUMAN def: "Calcium/calmodulin-dependent protein kinase type II alpha chain" [UniProtKB:Q9UQM7] synonym: "CaM kinase II subunit alpha" EXACT [UniProtKB:Q9UQM7] synonym: "CaM-kinase II alpha chain" EXACT [UniProtKB:Q9UQM7] synonym: "CaMK-II subunit alpha" EXACT [UniProtKB:Q9UQM7] synonym: "EC 2.7.11.17" EXACT [UniProtKB:Q9UQM7] xref: EMBL:AAD30558.1 xref: EMBL:AAD30559.1 xref: EMBL:BAA76812.1 xref: UniProtKB:Q9UL21 xref: UniProtKB:Q9UQM7 xref: UniProtKB:Q9Y2H4 xref: UniProtKB:Q9Y352 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007729 ! CAMK2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0034989 ! KCC2A_HUMAN-Phosphotyrosine13 relationship: transforms_into CCO:B0034990 ! KCC2A_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0034991 ! KCC2A_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0034992 ! KCC2A_HUMAN-Phosphothreonine286 relationship: transforms_into CCO:B0034993 ! KCC2A_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0034994 ! KCC2A_HUMAN-Phosphothreonine334 relationship: transforms_into CCO:B0034995 ! KCC2A_HUMAN-Phosphothreonine337 [Term] id: CCO:B0016638 name: Q0VAF8_HUMAN def: "LOC729862 protein" [UniProtKB:Q0VAF8] xref: EMBL:AAI21075.1 xref: UniProtKB:Q0VAF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008508 ! LOC729862_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016650 name: FCERB_HUMAN def: "High affinity immunoglobulin epsilon receptor subunit beta" [UniProtKB:Q01362] synonym: "Fc epsilon receptor I beta-chain" EXACT [UniProtKB:Q01362] synonym: "FcERI" EXACT [UniProtKB:Q01362] synonym: "IgE Fc receptor subunit beta" EXACT [UniProtKB:Q01362] synonym: "Membrane-spanning 4-domains subfamily A member 2" EXACT [UniProtKB:Q01362] xref: EMBL:AAA60269.1 xref: EMBL:AAH74800.1 xref: EMBL:AAH74843.1 xref: EMBL:BAA01440.1 xref: UniProtKB:Q01362 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007528 ! MS4A2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0034785 ! FCERB_HUMAN-Phosphotyrosine219 relationship: transforms_into CCO:B0034786 ! FCERB_HUMAN-Phosphotyrosine225 relationship: transforms_into CCO:B0034787 ! FCERB_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0034788 ! FCERB_HUMAN-Phosphotyrosine229 [Term] id: CCO:B0016653 name: Q5PU80_HUMAN def: "Nucleostemin" [UniProtKB:Q5PU80] xref: EMBL:AAV74413.1 xref: UniProtKB:Q5PU80 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022834 ! NS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020249 ! ascc2-ns physical interaction [Term] id: CCO:B0016679 name: A6NJF2_HUMAN def: "Putative uncharacterized protein NPR2 (Natriuretic peptide receptor B/guanylate cyclase B (Atrionatriuretic peptide receptor B) variant 3)" [UniProtKB:A6NJF2] xref: EMBL:ACA05922.1 xref: UniProtKB:A6NJF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007250 ! NPR2_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0016680 name: ANPRA_HUMAN def: "Atrial natriuretic peptide receptor A precursor" [UniProtKB:P16066] synonym: "ANP-A" EXACT [UniProtKB:P16066] synonym: "ANPRA" EXACT [UniProtKB:P16066] synonym: "Atrial natriuretic peptide A-type receptor" EXACT [UniProtKB:P16066] synonym: "EC 4.6.1.2" EXACT [UniProtKB:P16066] synonym: "GC-A" EXACT [UniProtKB:P16066] synonym: "Guanylate cyclase" EXACT [UniProtKB:P16066] synonym: "NPR-A" EXACT [UniProtKB:P16066] xref: EMBL:AAD14112.1 xref: EMBL:AAF01340.1 xref: EMBL:AAH63304.1 xref: EMBL:BAA31199.1 xref: EMBL:CAA33417.1 xref: EMBL:CAI13613.1 xref: UniProtKB:P16066 xref: UniProtKB:Q5SR08 xref: UniProtKB:Q6P4Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007249 ! NPR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: transforms_into CCO:B0034544 ! ANPRA_HUMAN-Phosphoserine529 relationship: transforms_into CCO:B0034545 ! ANPRA_HUMAN-Phosphothreonine532 relationship: transforms_into CCO:B0034546 ! ANPRA_HUMAN-Phosphoserine534 relationship: transforms_into CCO:B0034547 ! ANPRA_HUMAN-Phosphoserine538 relationship: transforms_into CCO:B0034548 ! ANPRA_HUMAN-Phosphoserine542 relationship: transforms_into CCO:B0034549 ! ANPRA_HUMAN-Phosphothreonine545 [Term] id: CCO:B0016681 name: ANPRB_HUMAN def: "Atrial natriuretic peptide receptor B precursor" [UniProtKB:P20594] synonym: "ANP-B" EXACT [UniProtKB:P20594] synonym: "ANPRB" EXACT [UniProtKB:P20594] synonym: "Atrial natriuretic peptide B-type receptor" EXACT [UniProtKB:P20594] synonym: "EC 4.6.1.2" EXACT [UniProtKB:P20594] synonym: "GC-B" EXACT [UniProtKB:P20594] synonym: "Guanylate cyclase B" EXACT [UniProtKB:P20594] synonym: "NPR-B" EXACT [UniProtKB:P20594] xref: EMBL:AAH23017.1 xref: EMBL:BAA81737.1 xref: EMBL:CAA06466.1 xref: EMBL:CAI10987.1 xref: UniProtKB:O60871 xref: UniProtKB:P20594 xref: UniProtKB:Q4VAK7 xref: UniProtKB:Q5TCV2 xref: UniProtKB:Q8TA93 xref: UniProtKB:Q9UQ50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007250 ! NPR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0034550 ! ANPRB_HUMAN-Phosphoserine513 relationship: transforms_into CCO:B0034551 ! ANPRB_HUMAN-Phosphothreonine516 relationship: transforms_into CCO:B0034552 ! ANPRB_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0034553 ! ANPRB_HUMAN-Phosphoserine523 relationship: transforms_into CCO:B0034554 ! ANPRB_HUMAN-Phosphoserine526 [Term] id: CCO:B0016682 name: GUC2D_HUMAN def: "Retinal guanylyl cyclase 1 precursor" [UniProtKB:Q02846] synonym: "EC 4.6.1.2" EXACT [UniProtKB:Q02846] synonym: "Guanylate cyclase 2D, retinal" EXACT [UniProtKB:Q02846] synonym: "RETGC-1" EXACT [UniProtKB:Q02846] synonym: "Rod outer segment membrane guanylate cyclase" EXACT [UniProtKB:Q02846] synonym: "ROS-GC" EXACT [UniProtKB:Q02846] xref: EMBL:AAA60366.1 xref: EMBL:AAA60547.1 xref: EMBL:CAA10914.1 xref: UniProtKB:Q02846 xref: UniProtKB:Q6LEA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007612 ! GUCY2D_human relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000257 ! nuclear outer membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000711 ! receptor guanylyl cyclase signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0016684 name: GUC2F_HUMAN def: "Retinal guanylyl cyclase 2 precursor" [UniProtKB:P51841] synonym: "EC 4.6.1.2" EXACT [UniProtKB:P51841] synonym: "GC-F" EXACT [UniProtKB:P51841] synonym: "Guanylate cyclase 2F, retinal" EXACT [UniProtKB:P51841] synonym: "Guanylate cyclase F" EXACT [UniProtKB:P51841] synonym: "RETGC-2" EXACT [UniProtKB:P51841] synonym: "Rod outer segment membrane guanylate cyclase 2" EXACT [UniProtKB:P51841] synonym: "ROS-GC2" EXACT [UniProtKB:P51841] xref: EMBL:AAA74451.1 xref: EMBL:CAB41303.1 xref: UniProtKB:P51841 xref: UniProtKB:Q9UJF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007613 ! GUCY2F_human relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000257 ! nuclear outer membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000711 ! receptor guanylyl cyclase signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0016685 name: GUC2C_HUMAN def: "Heat-stable enterotoxin receptor precursor" [UniProtKB:P25092] synonym: "EC 4.6.1.2" EXACT [UniProtKB:P25092] synonym: "GC-C" EXACT [UniProtKB:P25092] synonym: "hSTAR" EXACT [UniProtKB:P25092] synonym: "Intestinal guanylate cyclase" EXACT [UniProtKB:P25092] synonym: "STA receptor" EXACT [UniProtKB:P25092] xref: EMBL:AAA36655.1 xref: EMBL:AAB19934.2 xref: EMBL:AAC50381.1 xref: UniProtKB:P25092 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007611 ! GUCY2C_human relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000711 ! receptor guanylyl cyclase signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0016694 name: FOXI1_HUMAN def: "Forkhead box protein I1" [UniProtKB:Q12951] synonym: "Forkhead-related protein FKHL10" EXACT [UniProtKB:Q12951] synonym: "Forkhead-related transcription factor 6" EXACT [UniProtKB:Q12951] synonym: "FREAC-6" EXACT [UniProtKB:Q12951] synonym: "Hepatocyte nuclear factor 3 forkhead homolog 3" EXACT [UniProtKB:Q12951] synonym: "HFH-3" EXACT [UniProtKB:Q12951] synonym: "HNF-3/fork-head homolog 3" EXACT [UniProtKB:Q12951] xref: EMBL:AAA92041.1 xref: EMBL:AAB50574.1 xref: EMBL:AAH29778.2 xref: EMBL:AAU12169.1 xref: UniProtKB:Q12951 xref: UniProtKB:Q14518 xref: UniProtKB:Q66SR7 xref: UniProtKB:Q8N6L8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007547 ! FOXI1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0016695 name: FOXE1_HUMAN def: "Forkhead box protein E1" [UniProtKB:O00358] synonym: "Forkhead box protein E2" EXACT [UniProtKB:O00358] synonym: "Forkhead-related protein FKHL15" EXACT [UniProtKB:O00358] synonym: "HFKH4" EXACT [UniProtKB:O00358] synonym: "HFKL5" EXACT [UniProtKB:O00358] synonym: "HNF-3/fork head-like protein 5" EXACT [UniProtKB:O00358] synonym: "Thyroid transcription factor 2" EXACT [UniProtKB:O00358] synonym: "TTF-2" EXACT [UniProtKB:O00358] xref: EMBL:AAC51294.1 xref: EMBL:CAA64246.1 xref: EMBL:CAA73816.1 xref: EMBL:CAI12803.1 xref: EMBL:EAW58856.1 xref: UniProtKB:O00358 xref: UniProtKB:O75765 xref: UniProtKB:Q5T109 xref: UniProtKB:Q99526 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007542 ! FOXE1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0016696 name: FOXD2_HUMAN def: "Forkhead box protein D2" [UniProtKB:O60548] synonym: "Forkhead-related protein FKHL17" EXACT [UniProtKB:O60548] synonym: "Forkhead-related transcription factor 9" EXACT [UniProtKB:O60548] synonym: "FREAC-9" EXACT [UniProtKB:O60548] xref: EMBL:AAC15421.1 xref: EMBL:CAI14974.1 xref: UniProtKB:O60548 xref: UniProtKB:Q5SVZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007539 ! FOXD2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016698 name: FX4L4_HUMAN def: "Forkhead box protein D4-like 4" [UniProtKB:Q8WXT5] synonym: "Forkhead box protein D4B" EXACT [UniProtKB:Q8WXT5] synonym: "FOXD4-like 4" EXACT [UniProtKB:Q8WXT5] synonym: "Myeloid factor-gamma" EXACT [UniProtKB:Q8WXT5] xref: EMBL:AAL73342.1 xref: EMBL:CAI14283.1 xref: UniProtKB:Q5RIB4 xref: UniProtKB:Q8WXT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007563 ! FOXD4L4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016699 name: FOXF1_HUMAN def: "Forkhead box protein F1" [UniProtKB:Q12946] synonym: "Forkhead-related activator 1" EXACT [UniProtKB:Q12946] synonym: "Forkhead-related protein FKHL5" EXACT [UniProtKB:Q12946] synonym: "Forkhead-related transcription factor 1" EXACT [UniProtKB:Q12946] synonym: "FREAC-1" EXACT [UniProtKB:Q12946] xref: EMBL:AAC50399.1 xref: EMBL:AAC61576.1 xref: EMBL:AAH89442.1 xref: UniProtKB:Q12946 xref: UniProtKB:Q5FWE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007544 ! FOXF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0016702 name: Q4JHB7_HUMAN def: "Transcription factor FOXL2 mutant 1" [UniProtKB:Q4JHB7] xref: EMBL:AAY89234.1 xref: UniProtKB:Q4JHB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007549 ! FOXL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016703 name: Q6VB86_HUMAN def: "FOXD4" [UniProtKB:Q6VB86] xref: EMBL:AAQ76878.1 xref: UniProtKB:Q6VB86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007541 ! FOXD4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016706 name: FOXD1_HUMAN def: "Forkhead box protein D1" [UniProtKB:Q16676] synonym: "Forkhead-related protein FKHL8" EXACT [UniProtKB:Q16676] synonym: "Forkhead-related transcription factor 4" EXACT [UniProtKB:Q16676] synonym: "FREAC-4" EXACT [UniProtKB:Q16676] xref: EMBL:AAA92039.1 xref: EMBL:AAC50660.1 xref: EMBL:AAC50661.1 xref: UniProtKB:Q12949 xref: UniProtKB:Q16676 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007538 ! FOXD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016708 name: FX4L1_HUMAN def: "Forkhead box protein D4-like 1" [UniProtKB:Q9NU39] synonym: "FOXD4-like 1" EXACT [UniProtKB:Q9NU39] xref: EMBL:AAN64908.1 xref: EMBL:AAQ76877.1 xref: EMBL:CAB81641.1 xref: UniProtKB:Q9NU39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007560 ! FOXD4L1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016714 name: FOXB2_HUMAN def: "Forkhead box protein B2" [UniProtKB:Q5VYV0] xref: EMBL:CAH70683.1 xref: UniProtKB:Q5VYV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007536 ! FOXB2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016715 name: FOXQ1_HUMAN def: "Forkhead box protein Q1" [UniProtKB:Q9C009] synonym: "Hepatocyte nuclear factor 3 forkhead homolog 1" EXACT [UniProtKB:Q9C009] synonym: "HFH-1" EXACT [UniProtKB:Q9C009] synonym: "HNF-3/forkhead-like protein 1" EXACT [UniProtKB:Q9C009] xref: EMBL:AAF75586.1 xref: EMBL:AAH53850.1 xref: EMBL:AAK00639.1 xref: UniProtKB:Q9C009 xref: UniProtKB:Q9NS06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007553 ! FOXQ1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016719 name: FOXF2_HUMAN def: "Forkhead box protein F2" [UniProtKB:Q12947] synonym: "Forkhead-related activator 2" EXACT [UniProtKB:Q12947] synonym: "Forkhead-related protein FKHL6" EXACT [UniProtKB:Q12947] synonym: "Forkhead-related transcription factor 2" EXACT [UniProtKB:Q12947] synonym: "FREAC-2" EXACT [UniProtKB:Q12947] xref: EMBL:AAC32226.1 xref: EMBL:AAD19875.1 xref: UniProtKB:Q12947 xref: UniProtKB:Q9UQ85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007545 ! FOXF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0016720 name: FX4L5_HUMAN def: "Forkhead box protein D4-like 5" [UniProtKB:Q5VV16] synonym: "FOXD4-like 5" EXACT [UniProtKB:Q5VV16] xref: EMBL:CAH70699.1 xref: UniProtKB:Q5VV16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007564 ! FOXD4L5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016722 name: FOXL1_HUMAN def: "Forkhead box protein L1" [UniProtKB:Q12952] synonym: "Forkhead-related protein FKHL11" EXACT [UniProtKB:Q12952] synonym: "Forkhead-related transcription factor 7" EXACT [UniProtKB:Q12952] synonym: "FREAC-7" EXACT [UniProtKB:Q12952] xref: EMBL:AAA92042.1 xref: EMBL:AAG40312.1 xref: EMBL:AAI17227.1 xref: UniProtKB:Q12952 xref: UniProtKB:Q17RR1 xref: UniProtKB:Q9H242 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007548 ! FOXL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016723 name: Q8WXT4_HUMAN def: "Winged helix transcription factor delta" [UniProtKB:Q8WXT4] xref: EMBL:AAL73344.1 xref: UniProtKB:Q8WXT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016724 name: FX4L6_HUMAN def: "Forkhead box protein D4-like 6" [UniProtKB:Q3SYB3] synonym: "FOXD4-like 6" EXACT [UniProtKB:Q3SYB3] xref: EMBL:AAI03888.1 xref: EMBL:CAI94919.1 xref: UniProtKB:Q3SYB3 xref: UniProtKB:Q4V336 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007565 ! FOXD4L6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016726 name: Q14CL2_HUMAN xref: UniProtKB:Q14CL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016727 name: FOXE3_HUMAN def: "Forkhead box protein E3" [UniProtKB:Q13461] synonym: "Forkhead-related protein FKHL12" EXACT [UniProtKB:Q13461] synonym: "Forkhead-related transcription factor 8" EXACT [UniProtKB:Q13461] synonym: "FREAC-8" EXACT [UniProtKB:Q13461] xref: EMBL:AAB48856.1 xref: EMBL:AAF82793.1 xref: EMBL:CAI14973.1 xref: UniProtKB:Q13461 xref: UniProtKB:Q5SVY9 xref: UniProtKB:Q9NQV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007543 ! FOXE3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0016732 name: FOXC2_HUMAN def: "Forkhead box protein C2" [UniProtKB:Q99958] synonym: "Forkhead-related protein FKHL14" EXACT [UniProtKB:Q99958] synonym: "Mesenchyme fork head protein 1" EXACT [UniProtKB:Q99958] synonym: "MFH-1 protein" EXACT [UniProtKB:Q99958] synonym: "Transcription factor FKH-14" EXACT [UniProtKB:Q99958] xref: EMBL:AAI13438.1 xref: EMBL:AAI13440.1 xref: EMBL:CAA69400.1 xref: UniProtKB:Q14DA6 xref: UniProtKB:Q99958 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007537 ! FOXC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0003231 ! cardiac muscle cell proliferation relationship: transforms_into CCO:B0034794 ! FOXC2_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0034795 ! FOXC2_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0034796 ! FOXC2_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0052384 ! FOXC2_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0052385 ! FOXC2_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0066254 ! FOXC2_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0066255 ! FOXC2_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0066256 ! FOXC2_HUMAN-Phosphoserine288 [Term] id: CCO:B0016733 name: FOXD3_HUMAN def: "Forkhead box protein D3" [UniProtKB:Q9UJU5] synonym: "HNF3/FH transcription factor genesis" EXACT [UniProtKB:Q9UJU5] xref: EMBL:AAF05844.1 xref: EMBL:AAK13574.1 xref: EMBL:CAC19431.1 xref: UniProtKB:Q9BYM2 xref: UniProtKB:Q9UDD1 xref: UniProtKB:Q9UJU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007540 ! FOXD3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016240 ! foxd3-pou5f1-1 physical interaction relationship: participates_in CCO:I0016241 ! foxd3-pou5f1-2 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0016737 name: FX4L3_HUMAN def: "Forkhead box protein D4-like 3" [UniProtKB:Q6VB84] synonym: "FOXD4-like 3" EXACT [UniProtKB:Q6VB84] xref: EMBL:AAQ76880.1 xref: UniProtKB:Q6VB84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007562 ! FOXD4L3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016740 name: FOXG1_HUMAN def: "Forkhead box protein G1" [UniProtKB:P55316] synonym: "BF1" EXACT [UniProtKB:P55316] synonym: "BF2" EXACT [UniProtKB:P55316] synonym: "Brain factor 1" EXACT [UniProtKB:P55316] synonym: "Brain factor 2" EXACT [UniProtKB:P55316] synonym: "Forkhead box protein G1A" EXACT [UniProtKB:P55316] synonym: "Forkhead box protein G1B" EXACT [UniProtKB:P55316] synonym: "Forkhead box protein G1C" EXACT [UniProtKB:P55316] synonym: "Forkhead-related protein FKHL1" EXACT [UniProtKB:P55316] synonym: "Forkhead-related protein FKHL2" EXACT [UniProtKB:P55316] synonym: "Forkhead-related protein FKHL3" EXACT [UniProtKB:P55316] synonym: "hBF-2" EXACT [UniProtKB:P55316] synonym: "HFK1" EXACT [UniProtKB:P55316] synonym: "HFK2" EXACT [UniProtKB:P55316] synonym: "HFK3" EXACT [UniProtKB:P55316] synonym: "Transcription factor BF-1" EXACT [UniProtKB:P55316] synonym: "Transcription factor BF-2" EXACT [UniProtKB:P55316] xref: EMBL:AAH50072.1 xref: EMBL:CAA52239.1 xref: EMBL:CAA52240.1 xref: EMBL:CAA52241.1 xref: EMBL:CAA55038.1 xref: EMBL:EAW65978.1 xref: UniProtKB:A6NFY2 xref: UniProtKB:P55315 xref: UniProtKB:P55316 xref: UniProtKB:Q14488 xref: UniProtKB:Q86XT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007546 ! FOXG1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016741 name: Q5T109_HUMAN xref: UniProtKB:Q5T109 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016782 name: ACL6B_HUMAN def: "Actin-like protein 6B" [UniProtKB:O94805] synonym: "53 kDa BRG1-associated factor B" EXACT [UniProtKB:O94805] synonym: "Actin-related protein Baf53b" EXACT [UniProtKB:O94805] synonym: "ArpNalpha" EXACT [UniProtKB:O94805] xref: EMBL:AAC78795.1 xref: EMBL:AAD54678.1 xref: EMBL:AAH20944.1 xref: EMBL:AAP21874.1 xref: EMBL:BAA74576.1 xref: UniProtKB:O75421 xref: UniProtKB:O94805 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007204 ! ACTL6B_human relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: participates_in CCO:I0017487 ! act16b-smarca2-1 physical interaction [Term] id: CCO:B0016783 name: Q6FI97_HUMAN def: "BAF53A protein" [UniProtKB:Q6FI97] xref: EMBL:CAG38560.1 xref: UniProtKB:Q6FI97 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008745 ! BAF53A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020234 ! arhgdia-baf53a physical interaction [Term] id: CCO:B0016789 name: Q7Z5R8_HUMAN def: "Deleted in liver cancer 1" [UniProtKB:Q7Z5R8] xref: EMBL:AAH54511.1 xref: UniProtKB:Q7Z5R8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008101 ! DLC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016790 name: RHG07_HUMAN def: "Rho GTPase-activating protein 7" [UniProtKB:Q96QB1] synonym: "Deleted in liver cancer 1 protein" EXACT [UniProtKB:Q96QB1] synonym: "Dlc-1" EXACT [UniProtKB:Q96QB1] synonym: "HP protein" EXACT [UniProtKB:Q96QB1] synonym: "Rho-type GTPase-activating protein 7" EXACT [UniProtKB:Q96QB1] synonym: "StAR-related lipid transfer protein 12" EXACT [UniProtKB:Q96QB1] synonym: "StARD12" EXACT [UniProtKB:Q96QB1] synonym: "START domain-containing protein 12" EXACT [UniProtKB:Q96QB1] xref: EMBL:AAB81637.1 xref: EMBL:AAB87700.1 xref: EMBL:AAK97501.1 xref: EMBL:BAB21814.1 xref: UniProtKB:O14868 xref: UniProtKB:O43199 xref: UniProtKB:Q96QB1 xref: UniProtKB:Q9C0E0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008101 ! DLC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis relationship: participates_in CCO:P0001986 ! negative regulation of Rho protein signal transduction relationship: participates_in CCO:P0002020 ! positive regulation of protein amino acid dephosphorylation relationship: participates_in CCO:P0003109 ! negative regulation of stress fiber formation relationship: transforms_into CCO:B0035568 ! RHG07_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0035569 ! RHG07_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0035570 ! RHG07_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0035571 ! RHG07_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0035572 ! RHG07_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0035573 ! RHG07_HUMAN-Phosphothreonine312 relationship: transforms_into CCO:B0035574 ! RHG07_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0035575 ! RHG07_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0035576 ! RHG07_HUMAN-Phosphothreonine318 [Term] id: CCO:B0016794 name: PLAG1_HUMAN def: "Zinc finger protein PLAG1" [UniProtKB:Q6DJT9] synonym: "Pleiomorphic adenoma gene 1 protein" EXACT [UniProtKB:Q6DJT9] xref: EMBL:AAC50995.1 xref: EMBL:AAH75047.1 xref: EMBL:AAH75048.1 xref: EMBL:BAD92368.1 xref: UniProtKB:Q59GH8 xref: UniProtKB:Q6DJT9 xref: UniProtKB:Q9Y4L2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014927 ! PLAG1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0016798 name: PLAL2_HUMAN def: "Zinc finger protein PLAGL2" [UniProtKB:Q9UPG8] synonym: "Pleiomorphic adenoma-like protein 2" EXACT [UniProtKB:Q9UPG8] xref: EMBL:AAC34252.1 xref: EMBL:AAH23655.1 xref: EMBL:BAA12113.1 xref: EMBL:CAC16423.1 xref: UniProtKB:Q92584 xref: UniProtKB:Q9UPG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014928 ! PLAGL2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0016804 name: Q308M4_HUMAN def: "Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1" [UniProtKB:Q308M4] xref: EMBL:ABB29979.1 xref: UniProtKB:Q308M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001044 ! protein histidine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016805 name: PDK4_HUMAN def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor" [UniProtKB:Q16654] synonym: "EC 2.7.11.2" EXACT [UniProtKB:Q16654] synonym: "Pyruvate dehydrogenase kinase isoform 4" EXACT [UniProtKB:Q16654] xref: EMBL:AAB67048.1 xref: EMBL:AAC50669.1 xref: EMBL:AAC50670.1 xref: EMBL:AAH40239.1 xref: UniProtKB:Q16654 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007961 ! PDK4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035356 ! PDK4_HUMAN-Phosphohistidine127 [Term] id: CCO:B0016807 name: PDK1_HUMAN def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor" [UniProtKB:Q15118] synonym: "EC 2.7.11.2" EXACT [UniProtKB:Q15118] synonym: "Pyruvate dehydrogenase kinase isoform 1" EXACT [UniProtKB:Q15118] xref: EMBL:AAC42009.1 xref: EMBL:AAH39158.1 xref: UniProtKB:Q15118 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007958 ! PDK1_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001044 ! protein histidine kinase activity relationship: has_function CCO:F0001105 ! pyruvate dehydrogenase (acetyl-transferring) kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0016810 name: PDK3_HUMAN def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor" [UniProtKB:Q15120] synonym: "EC 2.7.11.2" EXACT [UniProtKB:Q15120] synonym: "Pyruvate dehydrogenase kinase isoform 3" EXACT [UniProtKB:Q15120] xref: EMBL:AAC42011.1 xref: EMBL:AAH15948.1 xref: UniProtKB:Q15120 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007960 ! PDK3_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001044 ! protein histidine kinase activity relationship: has_function CCO:F0001105 ! pyruvate dehydrogenase (acetyl-transferring) kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016811 name: PDK2_HUMAN def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor" [UniProtKB:Q15119] synonym: "EC 2.7.11.2" EXACT [UniProtKB:Q15119] synonym: "Pyruvate dehydrogenase kinase isoform 2" EXACT [UniProtKB:Q15119] xref: EMBL:AAC42010.1 xref: EMBL:AAH05811.1 xref: EMBL:AAH40478.1 xref: UniProtKB:Q15119 xref: UniProtKB:Q9BS05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007959 ! PDK2_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001044 ! protein histidine kinase activity relationship: has_function CCO:F0001105 ! pyruvate dehydrogenase (acetyl-transferring) kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0020622 ! pdk2-hd physical interaction relationship: participates_in CCO:I0020623 ! pdk2-hic2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016816 name: APBA3_HUMAN def: "Amyloid beta A4 precursor protein-binding family A member 3" [UniProtKB:O96018] synonym: "Adapter protein X11gamma" EXACT [UniProtKB:O96018] synonym: "Mint-3" EXACT [UniProtKB:O96018] synonym: "Neuron-specific X11L2 protein" EXACT [UniProtKB:O96018] synonym: "Neuronal Munc18-1-interacting protein 3" EXACT [UniProtKB:O96018] xref: EMBL:AAC17979.1 xref: EMBL:AAC72275.1 xref: EMBL:AAH86306.1 xref: EMBL:BAA74430.1 xref: UniProtKB:O60483 xref: UniProtKB:O96018 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016984 ! APBA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0065681 ! APBA3_HUMAN-Phosphoserine372 [Term] id: CCO:B0016826 name: GSK3B_HUMAN def: "Glycogen synthase kinase-3 beta" [UniProtKB:P49841] synonym: "EC 2.7.11.26" EXACT [UniProtKB:P49841] synonym: "GSK-3 beta" EXACT [UniProtKB:P49841] xref: EMBL:AAA66475.1 xref: EMBL:AAC69340.1 xref: EMBL:AAD48517.1 xref: EMBL:AAH00251.1 xref: EMBL:AAH12760.1 xref: UniProtKB:P49841 xref: UniProtKB:Q9BWH3 xref: UniProtKB:Q9UL47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007608 ! GSK3B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015865 ! gsk3b-nin-1 physical interaction relationship: participates_in CCO:I0017268 ! akt2-gsk3b-1 direct interaction relationship: participates_in CCO:I0017269 ! akt2-gsk3b-2 direct interaction relationship: participates_in CCO:I0018690 ! gsk3b-akt1-1 phosphorylation relationship: participates_in CCO:I0018694 ! gsk3b-gys-1 phosphorylation relationship: participates_in CCO:I0018720 ! gsk3b-nin-2 phosphorylation relationship: participates_in CCO:P0000684 ! ER overload response relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0003241 ! Wnt receptor signaling pathway through beta-catenin relationship: transforms_into CCO:B0034843 ! GSK3B_HUMAN-Phosphothreonine7 relationship: transforms_into CCO:B0034844 ! GSK3B_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0034845 ! GSK3B_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0034846 ! GSK3B_HUMAN-Phosphotyrosine216 relationship: transforms_into CCO:B0034847 ! GSK3B_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0034848 ! GSK3B_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0034849 ! GSK3B_HUMAN-Phosphothreonine390 relationship: transforms_into CCO:B0034850 ! GSK3B_HUMAN-Phosphothreonine395 [Term] id: CCO:B0016855 name: Q6TE15_HUMAN xref: UniProtKB:Q6TE15 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0016857 name: Q0MSE7_HUMAN xref: UniProtKB:Q0MSE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0016858 name: Q6JTU6_HUMAN xref: UniProtKB:Q6JTU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0016862 name: Q6V402_HUMAN xref: UniProtKB:Q6V402 is_a: CCO:B0000000 ! core cell cycle protein relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0016863 name: Q8WYM0_HUMAN xref: UniProtKB:Q8WYM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0016865 name: Q6TE14_HUMAN xref: UniProtKB:Q6TE14 is_a: CCO:B0000000 ! core cell cycle protein relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0016881 name: FOXO1_HUMAN def: "Forkhead box protein O1" [UniProtKB:Q12778] synonym: "Forkhead box protein O1A" EXACT [UniProtKB:Q12778] synonym: "Forkhead in rhabdomyosarcoma" EXACT [UniProtKB:Q12778] xref: EMBL:AAA03629.1 xref: EMBL:AAC39591.1 xref: EMBL:AAH21981.1 xref: EMBL:AAH70065.3 xref: EMBL:AAP36123.1 xref: EMBL:CAH70978.1 xref: EMBL:CAI16970.1 xref: UniProtKB:O43523 xref: UniProtKB:Q12778 xref: UniProtKB:Q5VYC7 xref: UniProtKB:Q6NSK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007551 ! FOXO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016204 ! esr1-foxo1a physical interaction relationship: participates_in CCO:I0018718 ! esr1-foxo1a-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0034797 ! FOXO1_HUMAN-Phosphothreonine24 relationship: transforms_into CCO:B0034798 ! FOXO1_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0034799 ! FOXO1_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0034800 ! FOXO1_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0034801 ! FOXO1_HUMAN-Phosphothreonine467 relationship: transforms_into CCO:B0034802 ! FOXO1_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0034803 ! FOXO1_HUMAN-Phosphoserine505 relationship: transforms_into CCO:B0034804 ! FOXO1_HUMAN-Phosphoserine509 relationship: transforms_into CCO:B0066271 ! FOXO1_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0066272 ! FOXO1_HUMAN-Phosphoserine322 relationship: transforms_into CCO:B0066273 ! FOXO1_HUMAN-Phosphoserine325 [Term] id: CCO:B0016909 name: A6NFH2_HUMAN def: "Putative uncharacterized protein TLE1" [UniProtKB:A6NFH2] xref: UniProtKB:A6NFH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005788 ! TLE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0016914 name: Q9Y6S1_HUMAN def: "R26610_1" [UniProtKB:Q9Y6S1] xref: EMBL:AAD38076.1 xref: UniProtKB:Q9Y6S1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0016921 name: A6NFJ3_HUMAN def: "Putative uncharacterized protein TLE2" [UniProtKB:A6NFJ3] xref: UniProtKB:A6NFJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005789 ! TLE2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0016924 name: TLE4_HUMAN def: "Transducin-like enhancer protein 4" [UniProtKB:Q04727] xref: EMBL:AAA61195.1 xref: EMBL:AAH45650.1 xref: EMBL:AAH59405.2 xref: EMBL:BAA86575.1 xref: EMBL:CAB82397.1 xref: EMBL:CAC22598.1 xref: EMBL:CAC22599.1 xref: EMBL:CAI13644.1 xref: EMBL:CAI13734.1 xref: EMBL:CAI41315.1 xref: UniProtKB:Q04727 xref: UniProtKB:Q3ZCS1 xref: UniProtKB:Q5T1Y2 xref: UniProtKB:Q6PCB3 xref: UniProtKB:Q9BZ07 xref: UniProtKB:Q9BZ08 xref: UniProtKB:Q9BZ09 xref: UniProtKB:Q9NSL3 xref: UniProtKB:Q9ULF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012946 ! TLE4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0039937 ! TLE4_HUMAN-Phosphoserine250 relationship: transforms_into CCO:B0039938 ! TLE4_HUMAN-Phosphoserine265 [Term] id: CCO:B0016926 name: A6NIY7_HUMAN def: "Putative uncharacterized protein TLE4" [UniProtKB:A6NIY7] xref: UniProtKB:A6NIY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012946 ! TLE4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0016937 name: BTAF1_HUMAN def: "TATA-binding protein-associated factor 172" [UniProtKB:O14981] synonym: "ATP-dependent helicase BTAF1" EXACT [UniProtKB:O14981] synonym: "B-TFIID transcription factor-associated 170 kDa subunit" EXACT [UniProtKB:O14981] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O14981] synonym: "TAF(II)170" EXACT [UniProtKB:O14981] synonym: "TAF-172" EXACT [UniProtKB:O14981] synonym: "TBP-associated factor 172" EXACT [UniProtKB:O14981] xref: EMBL:AAC04573.1 xref: EMBL:AAF37803.1 xref: EMBL:CAA04475.1 xref: UniProtKB:O14981 xref: UniProtKB:O43578 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007319 ! BTAF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0034607 ! BTAF1_HUMAN-Phosphoserine237 relationship: transforms_into CCO:B0064009 ! BTAF1_HUMAN-Phosphotyrosine1359 [Term] id: CCO:B0016974 name: PK2L1_HUMAN def: "Polycystic kidney disease 2-like 1 protein" [UniProtKB:Q9P0L9] synonym: "Polycystin-2 homolog" EXACT [UniProtKB:Q9P0L9] synonym: "Polycystin-2L1" EXACT [UniProtKB:Q9P0L9] synonym: "Polycystin-L" EXACT [UniProtKB:Q9P0L9] synonym: "Polycystin-L1" EXACT [UniProtKB:Q9P0L9] xref: EMBL:AAD08695.1 xref: EMBL:AAD41638.1 xref: EMBL:AAD51859.1 xref: EMBL:AAF28108.1 xref: EMBL:AAH25665.1 xref: UniProtKB:O75972 xref: UniProtKB:Q9P0L9 xref: UniProtKB:Q9UP35 xref: UniProtKB:Q9UPA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007976 ! PKD2L1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001502 ! calcium activated cation channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0016983 name: Q8NH25_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH25] xref: EMBL:BAC05816.1 xref: UniProtKB:Q8NH25 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0016986 name: P2RY8_HUMAN def: "P2Y purinoceptor 8" [UniProtKB:Q86VZ1] synonym: "P2Y8" EXACT [UniProtKB:Q86VZ1] xref: EMBL:AAH43610.1 xref: EMBL:CAI39849.1 xref: UniProtKB:Q86VZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014905 ! P2RY8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0017050 name: Q6LES9_HUMAN def: "RFC5 protein" [UniProtKB:Q6LES9] xref: EMBL:CAG28579.1 xref: UniProtKB:Q6LES9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005473 ! RFC5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000281 ! DNA clamp loader activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000268 ! DNA replication factor C complex relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0017087 name: Q9Y5S5_HUMAN def: "DNA polymerase" [UniProtKB:Q9Y5S5] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9Y5S5] xref: EMBL:AAD44690.1 xref: UniProtKB:Q9Y5S5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008999 ! POLE1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0017093 name: Q59EA9_HUMAN def: "DNA polymerase" [UniProtKB:Q59EA9] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q59EA9] xref: EMBL:BAD93139.1 xref: UniProtKB:Q59EA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0017097 name: Z816A_HUMAN def: "Zinc finger protein 816A" [UniProtKB:Q0VGE8] xref: EMBL:AAI05740.1 xref: EMBL:AAI05741.1 xref: EMBL:AAI05931.1 xref: EMBL:CAH56373.1 xref: UniProtKB:Q0VGE8 xref: UniProtKB:Q3KR39 xref: UniProtKB:Q659B3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020540 ! ZNF816A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017101 name: ZN528_HUMAN def: "Zinc finger protein 528" [UniProtKB:Q3MIS6] xref: EMBL:AAI01713.1 xref: EMBL:AAI11951.1 xref: EMBL:BAB47456.1 xref: EMBL:CAD89949.1 xref: UniProtKB:Q3MIS6 xref: UniProtKB:Q86T88 xref: UniProtKB:Q96JK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020799 ! ZNF528_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017103 name: ZNF83_HUMAN def: "Zinc finger protein 83" [UniProtKB:P51522] synonym: "Zinc finger protein 816B" EXACT [UniProtKB:P51522] synonym: "Zinc finger protein HPF1" EXACT [UniProtKB:P51522] xref: EMBL:AAG41760.1 xref: UniProtKB:P51522 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020989 ! ZNF83_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017106 name: PDLI4_HUMAN def: "PDZ and LIM domain protein 4" [UniProtKB:P50479] synonym: "LIM protein RIL" EXACT [UniProtKB:P50479] synonym: "Reversion-induced LIM protein" EXACT [UniProtKB:P50479] xref: EMBL:AAC52072.1 xref: EMBL:AAD34646.1 xref: EMBL:AAD38070.1 xref: EMBL:AAH03096.1 xref: EMBL:AAH16765.1 xref: EMBL:CAA63767.1 xref: UniProtKB:P50479 xref: UniProtKB:Q96AT8 xref: UniProtKB:Q9BTW8 xref: UniProtKB:Q9Y292 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014911 ! PDLIM4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017338 ! znf408-pdlim4 physical interaction relationship: transforms_into CCO:B0052616 ! PDLI4_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0052617 ! PDLI4_HUMAN-Phosphoserine120 [Term] id: CCO:B0017118 name: ING2_HUMAN def: "Inhibitor of growth protein 2" [UniProtKB:Q9H160] synonym: "ING1Lp" EXACT [UniProtKB:Q9H160] synonym: "Inhibitor of growth 1-like protein" EXACT [UniProtKB:Q9H160] synonym: "p32" EXACT [UniProtKB:Q9H160] synonym: "p33ING2" EXACT [UniProtKB:Q9H160] xref: EMBL:AAG11395.1 xref: EMBL:AAG11396.1 xref: EMBL:AAH30128.1 xref: EMBL:BAA36419.1 xref: EMBL:CAC20567.1 xref: UniProtKB:O95698 xref: UniProtKB:Q9H160 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007674 ! ING2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000816 ! CCAAT-binding factor complex relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0017123 name: PROK2_HUMAN def: "Prokineticin-2 precursor" [UniProtKB:Q9HC23] synonym: "PK2" EXACT [UniProtKB:Q9HC23] synonym: "Protein Bv8 homolog" EXACT [UniProtKB:Q9HC23] xref: EMBL:AAG16893.2 xref: EMBL:AAH98162.1 xref: EMBL:AAK49919.1 xref: EMBL:AAR06657.1 xref: UniProtKB:Q53Z79 xref: UniProtKB:Q9HC23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019516 ! PROK2_human relationship: has_function CCO:F0000196 ! G-protein-coupled receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0017140 name: NEU2_HUMAN def: "Vasopressin-neurophysin 2-copeptin precursor" [UniProtKB:P01185] synonym: "AVP-NPII" EXACT [UniProtKB:P01185] xref: EMBL:AAA61291.1 xref: EMBL:AAA98772.1 xref: EMBL:AAB86629.1 xref: EMBL:AAI26197.1 xref: EMBL:AAI26225.1 xref: EMBL:CAA26935.1 xref: EMBL:CAA44681.1 xref: EMBL:CAA44682.1 xref: EMBL:CAC10205.1 xref: UniProtKB:A0AV35 xref: UniProtKB:O14935 xref: UniProtKB:P01185 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018756 ! AVP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001312 ! positive regulation of cAMP biosynthetic process relationship: transforms_into CCO:B0068577 ! NEU2_HUMAN-Glycine amide28 [Term] id: CCO:B0017141 name: NEU1_HUMAN def: "Oxytocin-neurophysin 1 precursor" [UniProtKB:P01178] synonym: "OT-NPI" EXACT [UniProtKB:P01178] xref: EMBL:AAA59977.1 xref: EMBL:AAA59979.1 xref: EMBL:AAA98806.1 xref: EMBL:AAH69144.1 xref: EMBL:AAI01842.1 xref: EMBL:AAI01844.1 xref: EMBL:AAL92860.1 xref: EMBL:CAA26936.1 xref: EMBL:CAC10204.1 xref: UniProtKB:P01178 xref: UniProtKB:Q3MIG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018755 ! OXT_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001482 ! neurohypophyseal hormone activity relationship: has_function CCO:F0004866 ! oxytocin receptor binding relationship: has_function CCO:F0004902 ! V1A vasopressin receptor binding relationship: has_function CCO:F0004903 ! V1B vasopressin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068576 ! NEU1_HUMAN-Glycine amide28 [Term] id: CCO:B0017165 name: DPOG1_HUMAN def: "DNA polymerase subunit gamma-1" [UniProtKB:P54098] synonym: "EC 2.7.7.7" EXACT [UniProtKB:P54098] synonym: "Mitochondrial DNA polymerase catalytic subunit" EXACT [UniProtKB:P54098] synonym: "PolG-alpha" EXACT [UniProtKB:P54098] xref: EMBL:AAC50712.1 xref: EMBL:AAH42571.1 xref: EMBL:AAH50559.1 xref: EMBL:AAM77583.1 xref: EMBL:BAA12223.1 xref: EMBL:CAA66719.1 xref: UniProtKB:P54098 xref: UniProtKB:Q8NFM2 xref: UniProtKB:Q92515 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014231 ! POLG_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000343 ! gamma DNA polymerase complex relationship: participates_in CCO:I0018214 ! polg-polg2-3 physical interaction relationship: participates_in CCO:I0018215 ! polg-polg2-4 physical interaction relationship: participates_in CCO:I0018864 ! polg-polg2-1 direct interaction relationship: participates_in CCO:I0019289 ! polg-polg2-2 physical interaction relationship: participates_in CCO:I0019442 ! polg-polg2-5 physical interaction relationship: participates_in CCO:I0019443 ! polg-polg2-6 physical interaction relationship: participates_in CCO:I0019444 ! dpol-gamma_human physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: participates_in CCO:P0000630 ! mitochondrial DNA replication [Term] id: CCO:B0017183 name: Q6IPW0_HUMAN def: "FLJ10404 protein" [UniProtKB:Q6IPW0] xref: EMBL:AAH71696.1 xref: UniProtKB:Q6IPW0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022839 ! FLJ10404_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019092 ! atxn1-flj10404 physical interaction [Term] id: CCO:B0017343 name: Q15300_HUMAN def: "RET tyrosine kinase/cAMP protein kinase A subunit RI" [UniProtKB:Q15300] xref: EMBL:AAA60266.2 xref: UniProtKB:Q15300 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021098 ! RET/PTC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001058 ! cAMP-dependent protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0017344 name: RET_HUMAN def: "Proto-oncogene tyrosine-protein kinase receptor ret precursor" [UniProtKB:P07949] synonym: "C-ret" EXACT [UniProtKB:P07949] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P07949] xref: EMBL:AAA36524.1 xref: EMBL:AAA36786.1 xref: EMBL:CAA31408.1 xref: EMBL:CAA33333.1 xref: EMBL:CAA33787.1 xref: EMBL:CAC14882.1 xref: UniProtKB:P07949 xref: UniProtKB:Q15250 xref: UniProtKB:Q9H4A2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019679 ! RET_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069885 ! RET_HUMAN-Phosphotyrosine806 relationship: transforms_into CCO:B0069886 ! RET_HUMAN-Phosphotyrosine809 relationship: transforms_into CCO:B0069887 ! RET_HUMAN-Phosphotyrosine900 relationship: transforms_into CCO:B0069888 ! RET_HUMAN-Phosphotyrosine905 relationship: transforms_into CCO:B0069889 ! RET_HUMAN-Phosphotyrosine981 relationship: transforms_into CCO:B0069890 ! RET_HUMAN-Phosphotyrosine1015 relationship: transforms_into CCO:B0069891 ! RET_HUMAN-Phosphotyrosine1062 relationship: transforms_into CCO:B0069892 ! RET_HUMAN-Phosphotyrosine1090 relationship: transforms_into CCO:B0069893 ! RET_HUMAN-Phosphotyrosine1096 [Term] id: CCO:B0017386 name: Q7Z651_HUMAN def: "CDC16 protein" [UniProtKB:Q7Z651] synonym: "CDC16 cell division cycle 16 homolog (S. cerevisiae), isoform CRA_h" EXACT [UniProtKB:Q7Z651] synonym: "Cell division cycle 16 homolog (S. cerevisiae)" EXACT [UniProtKB:Q7Z651] xref: EMBL:AAH10875.1 xref: EMBL:CAI15811.1 xref: EMBL:EAX09245.1 xref: UniProtKB:Q7Z651 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004283 ! CDC16_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0017403 name: THOC4_HUMAN def: "THO complex subunit 4" [UniProtKB:Q86V81] synonym: "Ally of AML-1 and LEF-1" EXACT [UniProtKB:Q86V81] synonym: "bZIP-enhancing factor BEF" EXACT [UniProtKB:Q86V81] synonym: "Tho4" EXACT [UniProtKB:Q86V81] synonym: "Transcriptional coactivator Aly/REF" EXACT [UniProtKB:Q86V81] xref: EMBL:AAD09608.1 xref: EMBL:AAH52302.1 xref: UniProtKB:O43672 xref: UniProtKB:Q86V81 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008289 ! THOC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018317 ! ddx48-thoc4-1 direct interaction relationship: transforms_into CCO:B0035779 ! THOC4_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035780 ! THOC4_HUMAN-Omega-N-methylated arginine50 relationship: transforms_into CCO:B0035781 ! THOC4_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0035782 ! THOC4_HUMAN-Omega-N-methylated arginine204 relationship: transforms_into CCO:B0071385 ! THOC4_HUMAN-Phosphoserine8 [Term] id: CCO:B0017421 name: MP2K2_HUMAN def: "Dual specificity mitogen-activated protein kinase kinase 2" [UniProtKB:P36507] synonym: "EC 2.7.12.2" EXACT [UniProtKB:P36507] synonym: "ERK activator kinase 2" EXACT [UniProtKB:P36507] synonym: "MAP kinase kinase 2" EXACT [UniProtKB:P36507] synonym: "MAPK/ERK kinase 2" EXACT [UniProtKB:P36507] synonym: "MAPKK 2" EXACT [UniProtKB:P36507] synonym: "MEK2" EXACT [UniProtKB:P36507] xref: EMBL:AAH00471.1 xref: EMBL:AAH18645.1 xref: UniProtKB:P36507 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007832 ! MAP2K2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016207 ! map2k2-araf-1 physical interaction relationship: participates_in CCO:I0016208 ! map2k2-raf1-1 physical interaction relationship: participates_in CCO:I0016209 ! map2k2-mapk2-1 physical interaction relationship: participates_in CCO:I0016210 ! map2k2-ksr-1 physical interaction relationship: participates_in CCO:I0019188 ! map2k2-araf-2 physical interaction relationship: participates_in CCO:I0019189 ! map2k2-araf-3 direct interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0035209 ! MP2K2_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0035210 ! MP2K2_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0035211 ! MP2K2_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0035212 ! MP2K2_HUMAN-Phosphothreonine394 relationship: transforms_into CCO:B0035213 ! MP2K2_HUMAN-Phosphothreonine396 [Term] id: CCO:B0017433 name: BPA1_HUMAN def: "Bullous pemphigoid antigen 1, isoforms 1/2/3/4/5/8" [UniProtKB:Q03001] synonym: "230 kDa bullous pemphigoid antigen" EXACT [UniProtKB:Q03001] synonym: "BPA" EXACT [UniProtKB:Q03001] synonym: "Dystonia musculorum protein" EXACT [UniProtKB:Q03001] synonym: "Dystonin" EXACT [UniProtKB:Q03001] synonym: "Hemidesmosomal plaque protein" EXACT [UniProtKB:Q03001] xref: EMBL:AAA35538.1 xref: EMBL:AAA35606.1 xref: EMBL:AAA52288.1 xref: EMBL:AAA57184.1 xref: EMBL:AAA57185.1 xref: EMBL:AAC50243.1 xref: EMBL:AAC50244.1 xref: EMBL:AAK63130.1 xref: EMBL:AAK63131.1 xref: EMBL:CAA41528.1 xref: EMBL:CAI22047.1 xref: UniProtKB:Q03001 xref: UniProtKB:Q12825 xref: UniProtKB:Q13266 xref: UniProtKB:Q13267 xref: UniProtKB:Q13775 xref: UniProtKB:Q5TF23 xref: UniProtKB:Q96J76 xref: UniProtKB:Q96QT5 xref: UniProtKB:Q9UGD7 xref: UniProtKB:Q9UGD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004183 ! DST_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0034589 ! BPA1_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0034590 ! BPA1_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0034591 ! BPA1_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0034592 ! BPA1_HUMAN-Phosphothreonine224 relationship: transforms_into CCO:B0034593 ! BPA1_HUMAN-Phosphothreonine226 [Term] id: CCO:B0017481 name: KC1D_HUMAN def: "Casein kinase I isoform delta" [UniProtKB:P48730] synonym: "CKI-delta" EXACT [UniProtKB:P48730] synonym: "CKId" EXACT [UniProtKB:P48730] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P48730] xref: EMBL:AAC50807.1 xref: EMBL:AAC50808.1 xref: EMBL:AAH03558.1 xref: EMBL:AAH15775.1 xref: EMBL:BAC10903.1 xref: UniProtKB:P48730 xref: UniProtKB:Q96KZ6 xref: UniProtKB:Q9BTN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007724 ! CSNK1D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0034983 ! KC1D_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0034984 ! KC1D_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0034985 ! KC1D_HUMAN-Phosphoserine382 relationship: transforms_into CCO:B0052505 ! KC1D_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0067261 ! KC1D_HUMAN-Phosphothreonine347 relationship: transforms_into CCO:B0067262 ! KC1D_HUMAN-Phosphothreonine349 relationship: transforms_into CCO:B0067263 ! KC1D_HUMAN-Phosphoserine384 [Term] id: CCO:B0017505 name: PSF2_HUMAN def: "DNA replication complex GINS protein PSF2" [UniProtKB:Q9Y248] synonym: "GINS complex subunit 2" EXACT [UniProtKB:Q9Y248] xref: EMBL:AAD34117.1 xref: EMBL:AAD39915.1 xref: EMBL:AAF86875.1 xref: EMBL:AAH03186.1 xref: EMBL:AAH10164.1 xref: EMBL:AAH62444.1 xref: EMBL:BAA91595.1 xref: EMBL:CAG33467.1 xref: UniProtKB:Q6IAG9 xref: UniProtKB:Q9Y248 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008029 ! GINS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015342 ! psf2-sld5 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0035486 ! PSF2_HUMAN-Phosphothreonine180 relationship: transforms_into CCO:B0035487 ! PSF2_HUMAN-Phosphoserine182 [Term] id: CCO:B0017509 name: FGF20_HUMAN def: "Fibroblast growth factor 20" [UniProtKB:Q9NP95] synonym: "FGF-20" EXACT [UniProtKB:Q9NP95] xref: EMBL:AAT85804.1 xref: EMBL:BAB03530.1 xref: EMBL:BAB03633.1 xref: UniProtKB:Q9NP95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017797 ! FGF20_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0017511 name: FGF22_HUMAN def: "Fibroblast growth factor 22 precursor" [UniProtKB:Q9HCT0] synonym: "FGF-22" EXACT [UniProtKB:Q9HCT0] xref: EMBL:AAQ89955.1 xref: EMBL:AAQ93357.1 xref: EMBL:BAB13479.1 xref: UniProtKB:Q9HCT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017799 ! FGF22_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0017601 name: ZNFX1_HUMAN def: "NFX1-type zinc finger-containing protein 1" [UniProtKB:Q9P2E3] xref: EMBL:BAA91264.1 xref: EMBL:BAA92102.1 xref: EMBL:BAA92642.1 xref: EMBL:BAB14149.1 xref: EMBL:BAB14696.1 xref: EMBL:CAC33877.1 xref: UniProtKB:Q9BQM7 xref: UniProtKB:Q9BQM8 xref: UniProtKB:Q9H8C1 xref: UniProtKB:Q9H9S2 xref: UniProtKB:Q9NUM1 xref: UniProtKB:Q9NWW1 xref: UniProtKB:Q9P2E3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008372 ! ZNFX1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001186 ! serine-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017622 name: 3BP5_HUMAN def: "SH3 domain-binding protein 5" [UniProtKB:O60239] synonym: "SH3 domain-binding protein that preferentially associates with BTK" EXACT [UniProtKB:O60239] xref: EMBL:AAH10123.2 xref: EMBL:BAA25922.1 xref: EMBL:CAI46220.1 xref: UniProtKB:O60239 xref: UniProtKB:Q5JWV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016846 ! SH3BP5_human relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0017445 ! disc1-sh3bp5 physical interaction relationship: participates_in CCO:I0017446 ! disc1-sh3bp5-1 physical interaction relationship: participates_in CCO:I0017447 ! exoc1-sh3bp5 physical interaction relationship: participates_in CCO:I0017452 ! sh3bp5-sos1 physical interaction relationship: participates_in CCO:I0017467 ! sh3bp5-tnks physical interaction relationship: participates_in CCO:I0018195 ! btk-sh3bp5-4 physical interaction relationship: participates_in CCO:I0018318 ! btk-sh3bp5-2 physical interaction relationship: participates_in CCO:I0018319 ! btk-sh3bp5-3 physical interaction relationship: participates_in CCO:I0019256 ! btk-sh3bp5-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0065198 ! 3BP5_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0065199 ! 3BP5_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0065200 ! 3BP5_HUMAN-Phosphoserine421 [Term] id: CCO:B0017668 name: FGF12_HUMAN def: "Fibroblast growth factor 12" [UniProtKB:P61328] synonym: "FGF-12" EXACT [UniProtKB:P61328] synonym: "FHF-1" EXACT [UniProtKB:P61328] synonym: "Fibroblast growth factor homologous factor 1" EXACT [UniProtKB:P61328] synonym: "Myocyte-activating factor" EXACT [UniProtKB:P61328] xref: EMBL:AAB18786.3 xref: EMBL:AAB18913.1 xref: EMBL:AAH22524.1 xref: UniProtKB:O35339 xref: UniProtKB:P61328 xref: UniProtKB:P70376 xref: UniProtKB:Q8TBG5 xref: UniProtKB:Q92912 xref: UniProtKB:Q93001 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017791 ! FGF12_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0017671 name: FGF16_HUMAN def: "Fibroblast growth factor 16" [UniProtKB:O43320] synonym: "FGF-16" EXACT [UniProtKB:O43320] xref: EMBL:BAA24956.1 xref: UniProtKB:O43320 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017794 ! FGF16_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0017676 name: FGF13_HUMAN def: "Fibroblast growth factor 13" [UniProtKB:Q92913] synonym: "FGF-13" EXACT [UniProtKB:Q92913] synonym: "FHF-2" EXACT [UniProtKB:Q92913] synonym: "Fibroblast growth factor homologous factor 2" EXACT [UniProtKB:Q92913] xref: EMBL:AAB18914.1 xref: EMBL:AAD16400.1 xref: EMBL:AAD16401.1 xref: EMBL:AAH12347.1 xref: EMBL:AAH34340.1 xref: EMBL:AAT70720.1 xref: UniProtKB:O95830 xref: UniProtKB:Q92913 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017792 ! FGF13_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0004382 ! protein kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0017677 name: FGF14_HUMAN def: "Fibroblast growth factor 14" [UniProtKB:Q92915] synonym: "FGF-14" EXACT [UniProtKB:Q92915] synonym: "FHF-4" EXACT [UniProtKB:Q92915] synonym: "Fibroblast growth factor homologous factor 4" EXACT [UniProtKB:Q92915] xref: EMBL:AAB18916.1 xref: EMBL:AAI00921.1 xref: EMBL:AAI00922.1 xref: EMBL:AAI00923.1 xref: EMBL:AAN16025.1 xref: EMBL:AAO31806.1 xref: EMBL:CAC42528.2 xref: EMBL:CAH73403.1 xref: EMBL:CAI15768.1 xref: EMBL:CAI15769.1 xref: EMBL:CAI15872.1 xref: EMBL:CAI15873.1 xref: EMBL:CAI16837.1 xref: UniProtKB:Q86YN7 xref: UniProtKB:Q92915 xref: UniProtKB:Q96QX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017793 ! FGF14_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0017679 name: FGF11_HUMAN def: "Fibroblast growth factor 11" [UniProtKB:Q92914] synonym: "FGF-11" EXACT [UniProtKB:Q92914] synonym: "FHF-3" EXACT [UniProtKB:Q92914] synonym: "Fibroblast growth factor homologous factor 3" EXACT [UniProtKB:Q92914] xref: EMBL:AAB18915.1 xref: EMBL:AAH32502.1 xref: EMBL:AAI08266.1 xref: EMBL:AAL15439.1 xref: EMBL:AAM11871.1 xref: UniProtKB:Q2YDX8 xref: UniProtKB:Q92914 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017790 ! FGF11_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0017727 name: A6NMM6_HUMAN def: "Putative uncharacterized protein MSH3" [UniProtKB:A6NMM6] xref: UniProtKB:A6NMM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005127 ! MSH3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0017773 name: T2R40_HUMAN def: "Taste receptor type 2 member 40" [UniProtKB:P59535] synonym: "G-protein coupled receptor 60" EXACT [UniProtKB:P59535] synonym: "T2R40" EXACT [UniProtKB:P59535] synonym: "T2R58" EXACT [UniProtKB:P59535] xref: EMBL:AAI01796.1 xref: EMBL:AAI01798.1 xref: EMBL:AAM19320.1 xref: EMBL:AAU21153.1 xref: UniProtKB:P59535 xref: UniProtKB:Q645W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008258 ! TAS2R40_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0017820 name: NOTC3_HUMAN def: "Neurogenic locus notch homolog protein 3 precursor" [UniProtKB:Q9UM47] synonym: "Notch 3" EXACT [UniProtKB:Q9UM47] xref: EMBL:AAB91371.1 xref: EMBL:AAC04897.1 xref: EMBL:AAC14346.1 xref: EMBL:AAC15789.1 xref: UniProtKB:Q9UEB3 xref: UniProtKB:Q9UM47 xref: UniProtKB:Q9UPL3 xref: UniProtKB:Q9Y6L8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007891 ! NOTCH3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation [Term] id: CCO:B0017844 name: TGFI1_HUMAN def: "Transforming growth factor beta-1-induced transcript 1 protein" [UniProtKB:O43294] synonym: "Androgen receptor-associated protein of 55 kDa" EXACT [UniProtKB:O43294] synonym: "Hic-5" EXACT [UniProtKB:O43294] synonym: "Hydrogen peroxide-inducible clone 5 protein" EXACT [UniProtKB:O43294] xref: EMBL:AAD22552.1 xref: EMBL:AAH01507.2 xref: EMBL:AAH01830.1 xref: EMBL:AAH17288.1 xref: EMBL:AAH32545.1 xref: EMBL:ABB96286.1 xref: EMBL:BAA24799.1 xref: UniProtKB:O43294 xref: UniProtKB:Q9BPW3 xref: UniProtKB:Q9Y2V5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008285 ! TGFB1I1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018898 ! ubqln4-tgfb1i1 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0035773 ! TGFI1_HUMAN-Phosphotyrosine38 relationship: transforms_into CCO:B0035774 ! TGFI1_HUMAN-Phosphotyrosine60 relationship: transforms_into CCO:B0035775 ! TGFI1_HUMAN-Phosphoserine68 relationship: transforms_into CCO:B0035776 ! TGFI1_HUMAN-Phosphoserine122 [Term] id: CCO:B0017845 name: LPXN_HUMAN def: "Leupaxin" [UniProtKB:O60711] xref: EMBL:AAC16014.1 xref: EMBL:AAH19035.1 xref: UniProtKB:O60711 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007791 ! LPXN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015108 ! lpxn-znf426 physical interaction relationship: participates_in CCO:I0015163 ! lpxn-phf21a physical interaction relationship: participates_in CCO:I0015341 ! imp3-lpxn physical interaction relationship: participates_in CCO:I0015349 ! lims1-lpxn physical interaction relationship: participates_in CCO:I0015662 ! hoxa1-lpxn physical interaction relationship: participates_in CCO:I0015789 ! lpxn-pom121 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035118 ! LPXN_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0035119 ! LPXN_HUMAN-Phosphotyrosine22 relationship: transforms_into CCO:B0035120 ! LPXN_HUMAN-Phosphotyrosine62 relationship: transforms_into CCO:B0035121 ! LPXN_HUMAN-Phosphotyrosine72 [Term] id: CCO:B0017875 name: ZFP62_HUMAN def: "Zinc finger protein 62 homolog" [UniProtKB:Q8NB50] synonym: "Zfp-62" EXACT [UniProtKB:Q8NB50] xref: EMBL:BAC03691.1 xref: EMBL:CAI46133.1 xref: UniProtKB:Q8NB50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020593 ! ZFP62_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072017 ! ZFP62_HUMAN-Phosphothreonine266 [Term] id: CCO:B0017876 name: Q6ZN27_HUMAN def: "cDNA FLJ16495 fis, clone CTONG3004726, moderately similar to Zinc finger protein 91" [UniProtKB:Q6ZN27] xref: EMBL:BAD18548.1 xref: UniProtKB:Q6ZN27 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017883 name: ZN616_HUMAN def: "Zinc finger protein 616" [UniProtKB:Q08AN1] xref: EMBL:AAH33199.1 xref: EMBL:AAI25100.1 xref: EMBL:CAH56353.1 xref: UniProtKB:Q08AN1 xref: UniProtKB:Q0P658 xref: UniProtKB:Q658V7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020857 ! ZNF616_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017884 name: ZN546_HUMAN def: "Zinc finger protein 546" [UniProtKB:Q86UE3] xref: EMBL:AAH45649.1 xref: UniProtKB:Q86UE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020808 ! ZNF546_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017892 name: A4D2A2_HUMAN def: "cDNA FLJ30817 fis, clone FEBRA2001581, highly similar to DNA REPLICATION LICENSING FACTOR MCM7" [UniProtKB:A4D2A2] synonym: "MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)" EXACT [UniProtKB:A4D2A2] synonym: "MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), isoform CRA_a" EXACT [UniProtKB:A4D2A2] xref: EMBL:BAG51508.1 xref: EMBL:EAL23856.1 xref: EMBL:EAW76598.1 xref: UniProtKB:A4D2A2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005042 ! MCM7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000634 ! DNA replication initiation [Term] id: CCO:B0017902 name: RBM38_HUMAN def: "RNA-binding protein 38" [UniProtKB:Q9H0Z9] synonym: "CLL-associated antigen KW-5" EXACT [UniProtKB:Q9H0Z9] synonym: "HSRNASEB" EXACT [UniProtKB:Q9H0Z9] synonym: "RNA-binding motif protein 38" EXACT [UniProtKB:Q9H0Z9] synonym: "RNA-binding region-containing protein 1" EXACT [UniProtKB:Q9H0Z9] synonym: "ssDNA-binding protein SEB4" EXACT [UniProtKB:Q9H0Z9] xref: EMBL:AAH18711.1 xref: EMBL:AAL99924.1 xref: EMBL:CAA53063.1 xref: EMBL:CAA53064.1 xref: EMBL:EAW75522.1 xref: UniProtKB:A6NDK1 xref: UniProtKB:A6NMU6 xref: UniProtKB:Q15350 xref: UniProtKB:Q15351 xref: UniProtKB:Q9BYK3 xref: UniProtKB:Q9BYK4 xref: UniProtKB:Q9H0Z9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010896 ! RBM38_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0000314 ! mRNA 3'-UTR binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000065 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest relationship: participates_in CCO:P0000683 ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0017927 name: MYST3_HUMAN def: "Histone acetyltransferase MYST3" [UniProtKB:Q92794] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q92794] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q92794] synonym: "Monocytic leukemia zinc finger protein" EXACT [UniProtKB:Q92794] synonym: "MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3" EXACT [UniProtKB:Q92794] synonym: "MYST protein 3" EXACT [UniProtKB:Q92794] synonym: "Runt-related transcription factor-binding protein 2" EXACT [UniProtKB:Q92794] synonym: "Zinc finger protein 220" EXACT [UniProtKB:Q92794] xref: EMBL:AAC50662.1 xref: EMBL:BAD00088.1 xref: UniProtKB:Q76L81 xref: UniProtKB:Q92794 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007858 ! MYST3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018937 ! atn1-myst3 physical interaction relationship: participates_in CCO:I0019050 ! atxn1-myst3 physical interaction relationship: participates_in CCO:I0019167 ! rere-myst3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0035239 ! MYST3_HUMAN-Phosphoserine473 relationship: transforms_into CCO:B0035240 ! MYST3_HUMAN-N6-acetyllysine815 relationship: transforms_into CCO:B0035241 ! MYST3_HUMAN-Phosphothreonine909 relationship: transforms_into CCO:B0035242 ! MYST3_HUMAN-Phosphoserine1113 relationship: transforms_into CCO:B0052607 ! MYST3_HUMAN-Phosphoserine941 relationship: transforms_into CCO:B0068425 ! MYST3_HUMAN-Phosphothreonine418 relationship: transforms_into CCO:B0068426 ! MYST3_HUMAN-Phosphoserine420 [Term] id: CCO:B0017931 name: MYST4_HUMAN def: "Histone acetyltransferase MYST4" [UniProtKB:Q8WYB5] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q8WYB5] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q8WYB5] synonym: "Histone acetyltransferase MORF" EXACT [UniProtKB:Q8WYB5] synonym: "Histone acetyltransferase MOZ2" EXACT [UniProtKB:Q8WYB5] synonym: "Monocytic leukemia zinc finger protein-related factor" EXACT [UniProtKB:Q8WYB5] synonym: "MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4" EXACT [UniProtKB:Q8WYB5] synonym: "MYST protein 4" EXACT [UniProtKB:Q8WYB5] xref: EMBL:AAF00095.1 xref: EMBL:AAF00099.1 xref: EMBL:AAF00100.1 xref: EMBL:AAH14143.1 xref: EMBL:AAH21128.1 xref: EMBL:AAH48199.1 xref: EMBL:AAL56647.1 xref: EMBL:BAA20837.2 xref: UniProtKB:O15087 xref: UniProtKB:Q86Y05 xref: UniProtKB:Q8WU81 xref: UniProtKB:Q8WYB5 xref: UniProtKB:Q9UKW2 xref: UniProtKB:Q9UKW3 xref: UniProtKB:Q9UKX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007859 ! MYST4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018938 ! atn1-myst4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0035243 ! MYST4_HUMAN-Phosphoserine1027 relationship: transforms_into CCO:B0035244 ! MYST4_HUMAN-Phosphothreonine1915 relationship: transforms_into CCO:B0052608 ! MYST4_HUMAN-Phosphoserine1048 [Term] id: CCO:B0017935 name: A7VJH3_HUMAN def: "Silent information regulator 2" [UniProtKB:A7VJH3] xref: EMBL:BAF76655.1 xref: UniProtKB:A7VJH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008453 ! SIR2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0017945 name: PURB_HUMAN def: "Transcriptional activator protein Pur-beta" [UniProtKB:Q96QR8] synonym: "Purine-rich element-binding protein B" EXACT [UniProtKB:Q96QR8] xref: EMBL:AAI01736.1 xref: EMBL:AAI01738.1 xref: EMBL:AAK72462.1 xref: EMBL:AAS00366.1 xref: UniProtKB:Q96QR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008040 ! PURB_human relationship: has_function CCO:F0000118 ! translation repressor activity, nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0004989 ! purine-rich negative regulatory element binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000267 ! DNA replication factor A complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002451 ! regulation of myeloid cell differentiation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035491 ! PURB_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035492 ! PURB_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0035493 ! PURB_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0035494 ! PURB_HUMAN-Phosphothreonine31 relationship: transforms_into CCO:B0035495 ! PURB_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0035496 ! PURB_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0052668 ! PURB_HUMAN-Phosphoserine101 [Term] id: CCO:B0017947 name: PHF5A_HUMAN def: "PHD finger-like domain-containing protein 5A" [UniProtKB:Q7RTV0] synonym: "PHD finger-like domain protein 5A" EXACT [UniProtKB:Q7RTV0] synonym: "SF3b14b" EXACT [UniProtKB:Q7RTV0] synonym: "Splicing factor 3B-associated 14 kDa protein" EXACT [UniProtKB:Q7RTV0] xref: EMBL:AAH07321.1 xref: EMBL:AAH75808.1 xref: EMBL:CAB62939.1 xref: EMBL:CAG30284.1 xref: EMBL:DAA00074.1 xref: UniProtKB:Q7RTV0 xref: UniProtKB:Q9UH06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007972 ! PHF5A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000288 ! snRNP U2 relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0017957 name: RFC4_HUMAN def: "Replication factor C subunit 4" [UniProtKB:P35249] synonym: "A1 37 kDa subunit" EXACT [UniProtKB:P35249] synonym: "Activator 1 37 kDa subunit" EXACT [UniProtKB:P35249] synonym: "Activator 1 subunit 4" EXACT [UniProtKB:P35249] synonym: "Replication factor C 37 kDa subunit" EXACT [UniProtKB:P35249] synonym: "RF-C 37 kDa subunit" EXACT [UniProtKB:P35249] synonym: "RFC37" EXACT [UniProtKB:P35249] xref: EMBL:AAB09785.1 xref: EMBL:AAH17452.1 xref: EMBL:AAH24022.1 xref: EMBL:AAM97933.1 xref: EMBL:AAP35633.1 xref: EMBL:CAG38798.1 xref: UniProtKB:P35249 xref: UniProtKB:Q6FHX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011652 ! RFC4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000281 ! DNA clamp loader activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000268 ! DNA replication factor C complex relationship: participates_in CCO:I0015821 ! rfc4-rfc5 physical interaction relationship: participates_in CCO:I0015869 ! rfc1-rfc2-2 physical interaction relationship: participates_in CCO:I0015870 ! rfc1-rfc2-3 physical interaction relationship: participates_in CCO:I0015871 ! rfc1-rfc2-4 physical interaction relationship: participates_in CCO:I0015872 ! rfc2-rfc3-1 physical interaction relationship: participates_in CCO:I0015873 ! rfc2-rfc4-4 physical interaction relationship: participates_in CCO:I0015874 ! rfc4-rfc3-2 physical interaction relationship: participates_in CCO:I0015875 ! rfc1-rfc3-1 physical interaction relationship: participates_in CCO:I0015876 ! rfc4-rfc3-3 physical interaction relationship: participates_in CCO:I0015877 ! rfc3-rfc4-1 physical interaction relationship: participates_in CCO:I0015878 ! rfc2-rfc4-5 physical interaction relationship: participates_in CCO:I0015879 ! rfc4-rfc5-1 physical interaction relationship: participates_in CCO:I0015908 ! rfc2-rfc4-1 physical interaction relationship: participates_in CCO:I0017805 ! rfc2-rfc3-3 physical interaction relationship: participates_in CCO:I0018606 ! rfc2-rfc4-2 physical interaction relationship: participates_in CCO:I0018607 ! rfc2-rfc4-3 physical interaction relationship: participates_in CCO:I0019330 ! rfc_human physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000635 ! DNA strand elongation during DNA replication relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0018007 name: RRAS_HUMAN def: "Ras-related protein R-Ras precursor" [UniProtKB:P10301] synonym: "p23" EXACT [UniProtKB:P10301] xref: EMBL:AAA60256.1 xref: EMBL:AAH16286.1 xref: EMBL:AAH16318.1 xref: EMBL:AAM12634.1 xref: EMBL:AAP35451.1 xref: UniProtKB:P10301 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008127 ! RRAS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: transforms_into CCO:B0035600 ! RRAS_HUMAN-Cysteine methyl ester215 [Term] id: CCO:B0018011 name: RRAS2_HUMAN def: "Ras-related protein R-Ras2 precursor" [UniProtKB:P62070] synonym: "Ras-like protein TC21" EXACT [UniProtKB:P62070] synonym: "Teratocarcinoma oncogene" EXACT [UniProtKB:P62070] xref: EMBL:AAA36545.1 xref: EMBL:AAH13106.1 xref: EMBL:AAM12638.1 xref: UniProtKB:P17082 xref: UniProtKB:P62070 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008126 ! RRAS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018051 ! araf-rras2 physical interaction relationship: participates_in CCO:I0018812 ! araf-rras2-1 physical interaction relationship: participates_in CCO:I0018821 ! araf-rras2-2 physical interaction relationship: participates_in CCO:I0019374 ! raf1-rras2 physical interaction relationship: participates_in CCO:I0020157 ! rras2-g22p1 physical interaction relationship: participates_in CCO:I0020443 ! rras2-lgals4 physical interaction relationship: participates_in CCO:I0020659 ! rras2-pawr physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000887 ! cellular process relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: transforms_into CCO:B0035598 ! RRAS2_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0035599 ! RRAS2_HUMAN-Cysteine methyl ester201 [Term] id: CCO:B0018024 name: ZPR1_HUMAN def: "Zinc finger protein ZPR1" [UniProtKB:O75312] synonym: "Zinc finger protein 259" EXACT [UniProtKB:O75312] xref: EMBL:AAC33514.1 xref: EMBL:AAH04256.1 xref: EMBL:AAH12162.1 xref: EMBL:AAH17349.1 xref: EMBL:AAH17380.1 xref: EMBL:AAI11029.1 xref: EMBL:AAP35288.1 xref: UniProtKB:O75312 xref: UniProtKB:Q2TAA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008374 ! ZNF259_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019946 ! cdk5rap2-znf259 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0018046 name: NXF1_HUMAN def: "Nuclear RNA export factor 1" [UniProtKB:Q9UBU9] synonym: "mRNA export factor TAP" EXACT [UniProtKB:Q9UBU9] synonym: "Tip-associated protein" EXACT [UniProtKB:Q9UBU9] synonym: "Tip-associating protein" EXACT [UniProtKB:Q9UBU9] xref: EMBL:AAB81111.1 xref: EMBL:AAD20016.1 xref: EMBL:AAD39102.1 xref: EMBL:AAH04904.1 xref: EMBL:AAH28041.1 xref: EMBL:CAA10753.1 xref: UniProtKB:Q99799 xref: UniProtKB:Q9UBU9 xref: UniProtKB:Q9UQL2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022466 ! NXF1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0001632 ! nucleocytoplasmic transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001640 ! nuclear inclusion body relationship: participates_in CCO:I0018317 ! ddx48-thoc4-1 direct interaction [Term] id: CCO:B0018116 name: Q6JSD6_HUMAN def: "Cell division cycle 7-like protein 1" [UniProtKB:Q6JSD6] xref: EMBL:AAR16187.1 xref: UniProtKB:Q6JSD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004294 ! CDC7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0018142 name: EVI5L_HUMAN def: "EVI5-like protein" [UniProtKB:Q96CN4] synonym: "Ecotropic viral integration site 5-like protein" EXACT [UniProtKB:Q96CN4] xref: EMBL:AAH14111.1 xref: UniProtKB:Q96CN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007508 ! EVI5L_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0018148 name: Q5JU07_HUMAN def: "CDC14 cell division cycle 14 homolog B (S. cerevisiae)" [UniProtKB:Q5JU07] xref: EMBL:CAI40540.1 xref: UniProtKB:Q5JU07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011275 ! CDC14B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0018153 name: Q5JU06_HUMAN def: "CDC14 cell division cycle 14 homolog B (S. cerevisiae)" [UniProtKB:Q5JU06] xref: EMBL:CAI40541.1 xref: UniProtKB:Q5JU06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011275 ! CDC14B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0018160 name: CC14B_HUMAN def: "Dual specificity protein phosphatase CDC14B" [UniProtKB:O60729] synonym: "CDC14 cell division cycle 14 homolog B" EXACT [UniProtKB:O60729] synonym: "EC 3.1.3.16" EXACT [UniProtKB:O60729] synonym: "EC 3.1.3.48" EXACT [UniProtKB:O60729] xref: EMBL:AAB88293.1 xref: EMBL:AAC16661.1 xref: EMBL:AAC16662.2 xref: EMBL:AAT70726.1 xref: EMBL:ABR12627.1 xref: EMBL:CAI39619.1 xref: EMBL:CAI40539.1 xref: UniProtKB:A6N5X8 xref: UniProtKB:O43183 xref: UniProtKB:O60729 xref: UniProtKB:O60730 xref: UniProtKB:Q5JU08 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011275 ! CDC14B_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction [Term] id: CCO:B0018166 name: ICK_HUMAN def: "Serine/threonine-protein kinase ICK" [UniProtKB:Q9UPZ9] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q9UPZ9] synonym: "hICK" EXACT [UniProtKB:Q9UPZ9] synonym: "Intestinal cell kinase" EXACT [UniProtKB:Q9UPZ9] synonym: "Laryngeal cancer kinase 2" EXACT [UniProtKB:Q9UPZ9] synonym: "LCK2" EXACT [UniProtKB:Q9UPZ9] synonym: "MAK-related kinase" EXACT [UniProtKB:Q9UPZ9] synonym: "MRK" EXACT [UniProtKB:Q9UPZ9] xref: EMBL:AAF37278.1 xref: EMBL:AAG43364.1 xref: EMBL:AAH35807.1 xref: EMBL:BAA76780.2 xref: EMBL:CAI19518.1 xref: EMBL:CAI20261.1 xref: UniProtKB:O75985 xref: UniProtKB:Q5THL2 xref: UniProtKB:Q8IYH8 xref: UniProtKB:Q9BX17 xref: UniProtKB:Q9NYX3 xref: UniProtKB:Q9UPZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007646 ! ICK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0034866 ! ICK_HUMAN-Phosphothreonine14 relationship: transforms_into CCO:B0034867 ! ICK_HUMAN-Phosphotyrosine15 relationship: transforms_into CCO:B0034868 ! ICK_HUMAN-Phosphothreonine157 relationship: transforms_into CCO:B0034869 ! ICK_HUMAN-Phosphotyrosine159 relationship: transforms_into CCO:B0067000 ! ICK_HUMAN-Phosphotyrosine156 [Term] id: CCO:B0018187 name: Q5JWU1_HUMAN def: "CDC91 cell division cycle 91-like 1 (S. cerevisiae)" [UniProtKB:Q5JWU1] xref: EMBL:CAI40292.2 xref: UniProtKB:Q5JWU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005314 ! CDC91L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0018189 name: PYDC1_HUMAN def: "Pyrin domain-containing protein 1" [UniProtKB:Q8WXC3] synonym: "PAAD-only protein 1" EXACT [UniProtKB:Q8WXC3] synonym: "Pyrin-only protein 1" EXACT [UniProtKB:Q8WXC3] xref: EMBL:AAI05034.1 xref: EMBL:AAI05036.1 xref: EMBL:AAL58439.1 xref: EMBL:AAN03745.1 xref: EMBL:AAO23114.1 xref: UniProtKB:Q8NFP8 xref: UniProtKB:Q8WXC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008041 ! PYDC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000547 ! IkappaB kinase complex relationship: participates_in CCO:P0001541 ! negative regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0001810 ! tumor necrosis factor-mediated signaling pathway [Term] id: CCO:B0018212 name: EZRI_HUMAN def: "Ezrin" [UniProtKB:P15311] synonym: "Cytovillin" EXACT [UniProtKB:P15311] synonym: "p81" EXACT [UniProtKB:P15311] synonym: "Villin-2" EXACT [UniProtKB:P15311] xref: EMBL:AAA61278.1 xref: EMBL:AAH13903.1 xref: EMBL:CAA35893.1 xref: EMBL:CAB82418.1 xref: EMBL:CAI95307.1 xref: UniProtKB:P15311 xref: UniProtKB:P23714 xref: UniProtKB:Q4VX75 xref: UniProtKB:Q96CU8 xref: UniProtKB:Q9NSJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008790 ! EZR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0034770 ! EZRI_HUMAN-Phosphotyrosine146 relationship: transforms_into CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 [Term] id: CCO:B0018220 name: MOES_HUMAN def: "Moesin" [UniProtKB:P26038] synonym: "Membrane-organizing extension spike protein" EXACT [UniProtKB:P26038] xref: EMBL:AAA36322.1 xref: EMBL:AAH17293.1 xref: EMBL:CAB46379.1 xref: UniProtKB:P26038 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007829 ! MSN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018190 ! msn-nherf-2 physical interaction relationship: participates_in CCO:I0018191 ! msn-nherf-3 physical interaction relationship: participates_in CCO:I0019366 ! msn-nherf-1 direct interaction relationship: transforms_into CCO:B0035200 ! MOES_HUMAN-N6-acetyllysine64 relationship: transforms_into CCO:B0035201 ! MOES_HUMAN-Phosphotyrosine116 relationship: transforms_into CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: transforms_into CCO:B0035203 ! MOES_HUMAN-Phosphoserine576 [Term] id: CCO:B0018239 name: SYUA_HUMAN def: "Alpha-synuclein" [UniProtKB:P37840] synonym: "NACP" EXACT [UniProtKB:P37840] synonym: "Non-A beta component of AD amyloid" EXACT [UniProtKB:P37840] synonym: "Non-A4 component of amyloid precursor" EXACT [UniProtKB:P37840] xref: EMBL:AAA16117.1 xref: EMBL:AAA98487.1 xref: EMBL:AAA98493.1 xref: EMBL:AAC02114.1 xref: EMBL:AAG30302.1 xref: EMBL:AAG30303.1 xref: EMBL:AAH13293.1 xref: EMBL:AAI08276.1 xref: EMBL:AAL15443.1 xref: EMBL:AAY88735.1 xref: EMBL:BAA06625.1 xref: EMBL:CAG33339.1 xref: UniProtKB:P37840 xref: UniProtKB:Q13701 xref: UniProtKB:Q4JHI3 xref: UniProtKB:Q6IAU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011701 ! SNCA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000510 ! positive regulation of neurotransmitter secretion relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002786 ! regulation of long-term neuronal synaptic plasticity relationship: transforms_into CCO:B0039664 ! SYUA_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0039665 ! SYUA_HUMAN-Phosphotyrosine125 relationship: transforms_into CCO:B0039666 ! SYUA_HUMAN-Phosphoserine129 [Term] id: CCO:B0018244 name: SMD2_HUMAN def: "Small nuclear ribonucleoprotein Sm D2" [UniProtKB:P62316] synonym: "Sm-D2" EXACT [UniProtKB:P62316] synonym: "snRNP core protein D2" EXACT [UniProtKB:P62316] xref: EMBL:AAC13776.1 xref: EMBL:AAD22673.1 xref: EMBL:AAH00486.1 xref: EMBL:AAH01930.1 xref: UniProtKB:P43330 xref: UniProtKB:P62316 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008191 ! SNRPD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0020171 ! snrpd2-htatip physical interaction relationship: participates_in CCO:I0020550 ! epb49-snrpd2 physical interaction relationship: transforms_into CCO:B0070644 ! SMD2_HUMAN-N-acetylserine2 [Term] id: CCO:B0018285 name: TF2H2_HUMAN def: "General transcription factor IIH subunit 2" [UniProtKB:Q13888] synonym: "Basic transcription factor 2 44 kDa subunit" EXACT [UniProtKB:Q13888] synonym: "BTF2-p44" EXACT [UniProtKB:Q13888] synonym: "General transcription factor IIH polypeptide 2" EXACT [UniProtKB:Q13888] synonym: "TFIIH basal transcription factor complex p44 subunit" EXACT [UniProtKB:Q13888] xref: EMBL:AAA64502.1 xref: EMBL:AAA64503.1 xref: EMBL:AAC52046.1 xref: EMBL:AAD44479.1 xref: EMBL:AAH05345.1 xref: EMBL:CAA82910.1 xref: UniProtKB:Q13888 xref: UniProtKB:Q15570 xref: UniProtKB:Q15571 xref: UniProtKB:Q9BS41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008282 ! GTF2H2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018345 name: O00334_HUMAN def: "Phosphatidylinositol 3-kinase delta catalytic subunit" [UniProtKB:O00334] xref: EMBL:AAB53966.1 xref: UniProtKB:O00334 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0006278 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0018350 name: PK3CA_HUMAN def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform" [UniProtKB:P42336] synonym: "EC 2.7.1.153" EXACT [UniProtKB:P42336] synonym: "PI3-kinase p110 subunit alpha" EXACT [UniProtKB:P42336] synonym: "PI3K" EXACT [UniProtKB:P42336] synonym: "PtdIns-3-kinase p110" EXACT [UniProtKB:P42336] xref: EMBL:AAB39753.1 xref: EMBL:AAI13602.1 xref: EMBL:AAI13604.1 xref: EMBL:CAA82333.1 xref: UniProtKB:P42336 xref: UniProtKB:Q14CW1 xref: UniProtKB:Q99762 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013616 ! PIK3CA_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0006278 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0018352 name: PK3CD_HUMAN def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform" [UniProtKB:O00329] synonym: "EC 2.7.1.153" EXACT [UniProtKB:O00329] synonym: "p110delta" EXACT [UniProtKB:O00329] synonym: "PI3-kinase p110 subunit delta" EXACT [UniProtKB:O00329] synonym: "PI3K" EXACT [UniProtKB:O00329] synonym: "PtdIns-3-kinase p110" EXACT [UniProtKB:O00329] xref: EMBL:AAC25677.1 xref: EMBL:AAI32920.1 xref: EMBL:AAI32922.1 xref: EMBL:ABB83814.1 xref: EMBL:CAA71149.2 xref: EMBL:CAI15703.1 xref: UniProtKB:A6NCG0 xref: UniProtKB:O00329 xref: UniProtKB:O15445 xref: UniProtKB:Q5SR49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013617 ! PIK3CD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020250 ! ascc2-pik3cd physical interaction relationship: participates_in CCO:I0020646 ! raly-pik3cd physical interaction relationship: participates_in CCO:I0020679 ! tnpo2-pik3cd physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0043340 ! PK3CD_HUMAN-Phosphoserine1039 relationship: transforms_into CCO:B0069320 ! PK3CD_HUMAN-Phosphotyrosine524 [Term] id: CCO:B0018367 name: ATF2_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-2" [UniProtKB:P15336] synonym: "Activating transcription factor 2" EXACT [UniProtKB:P15336] synonym: "cAMP response element-binding protein CRE-BP1" EXACT [UniProtKB:P15336] synonym: "HB16" EXACT [UniProtKB:P15336] xref: EMBL:AAA35951.1 xref: EMBL:AAB64017.1 xref: EMBL:AAX88876.1 xref: EMBL:AAY15004.1 xref: EMBL:CAA33886.1 xref: UniProtKB:P15336 xref: UniProtKB:Q13000 xref: UniProtKB:Q4ZFU9 xref: UniProtKB:Q53RY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007276 ! ATF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018412 ! mapk11-atf2 phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063651 ! ATF2_HUMAN-Phosphothreonine69 relationship: transforms_into CCO:B0063652 ! ATF2_HUMAN-Phosphothreonine71 relationship: transforms_into CCO:B0063653 ! ATF2_HUMAN-Phosphoserine112 relationship: transforms_into CCO:B0063654 ! ATF2_HUMAN-Phosphoserine328 [Term] id: CCO:B0018381 name: A1L3Z2_HUMAN def: "Activating transcription factor 2" [UniProtKB:A1L3Z2] synonym: "Activating transcription factor 2, isoform CRA_c" EXACT [UniProtKB:A1L3Z2] xref: EMBL:AAI30336.1 xref: EMBL:AAI30338.1 xref: EMBL:EAX11111.1 xref: UniProtKB:A1L3Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007276 ! ATF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0018382 name: CREB5_HUMAN def: "cAMP-responsive element-binding protein 5" [UniProtKB:Q02930] synonym: "CRE-BPa" EXACT [UniProtKB:Q02930] xref: EMBL:AAA52072.1 xref: EMBL:AAC37525.1 xref: EMBL:AAC37526.1 xref: EMBL:AAC37527.1 xref: EMBL:AAH59400.2 xref: EMBL:AAP22329.1 xref: UniProtKB:Q02930 xref: UniProtKB:Q05886 xref: UniProtKB:Q06246 xref: UniProtKB:Q86UJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017451 ! CREB5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0018386 name: IQGA1_HUMAN def: "Ras GTPase-activating-like protein IQGAP1" [UniProtKB:P46940] synonym: "p195" EXACT [UniProtKB:P46940] xref: EMBL:AAA59187.1 xref: EMBL:BAA06123.2 xref: UniProtKB:P46940 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007678 ! IQGAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015901 ! cdc42-iqgap1-2 physical interaction relationship: participates_in CCO:I0016394 ! nfkbib-iqgap1 physical interaction relationship: participates_in CCO:I0016453 ! ikbkb-iqgap1 physical interaction relationship: participates_in CCO:I0016681 ! map3k3-iqgap1 physical interaction relationship: participates_in CCO:I0016786 ! nfkb2-iqgap1 physical interaction relationship: participates_in CCO:I0019347 ! cdc42-iqgap1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0034879 ! IQGA1_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0034880 ! IQGA1_HUMAN-Phosphotyrosine172 relationship: transforms_into CCO:B0034881 ! IQGA1_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0034882 ! IQGA1_HUMAN-Phosphoserine1441 relationship: transforms_into CCO:B0034883 ! IQGA1_HUMAN-Phosphoserine1443 relationship: transforms_into CCO:B0067148 ! IQGA1_HUMAN-Phosphotyrosine654 relationship: transforms_into CCO:B0067149 ! IQGA1_HUMAN-Phosphotyrosine1510 [Term] id: CCO:B0018391 name: IQGA2_HUMAN def: "Ras GTPase-activating-like protein IQGAP2" [UniProtKB:Q13576] xref: EMBL:AAB37765.1 xref: EMBL:AAQ81291.1 xref: UniProtKB:Q13576 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007679 ! IQGAP2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:I0016768 ! map3k3-iqgap2 physical interaction relationship: participates_in CCO:I0017171 ! nfkbib-iqgap2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0052452 ! IQGA2_HUMAN-Phosphoserine16 [Term] id: CCO:B0018395 name: IQGA3_HUMAN def: "Ras GTPase-activating-like protein IQGAP3" [UniProtKB:Q86VI3] xref: EMBL:AAP06954.1 xref: EMBL:BAC78211.1 xref: EMBL:BAC85501.1 xref: UniProtKB:Q86VI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007680 ! IQGAP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0067150 ! IQGA3_HUMAN-Phosphoserine1424 relationship: transforms_into CCO:B0067151 ! IQGA3_HUMAN-Phosphotyrosine1537 [Term] id: CCO:B0018438 name: CCRL1_HUMAN def: "C-C chemokine receptor type 11" [UniProtKB:Q9NPB9] synonym: "C-C CKR-11" EXACT [UniProtKB:Q9NPB9] synonym: "CC chemokine receptor-like 1" EXACT [UniProtKB:Q9NPB9] synonym: "CC-CKR-11" EXACT [UniProtKB:Q9NPB9] synonym: "CCR-11" EXACT [UniProtKB:Q9NPB9] synonym: "CCRL1" EXACT [UniProtKB:Q9NPB9] synonym: "CCX CKR" EXACT [UniProtKB:Q9NPB9] xref: EMBL:AAF44751.1 xref: EMBL:AAF59827.1 xref: EMBL:AAF61299.1 xref: EMBL:AAH69438.1 xref: EMBL:AAO65972.1 xref: UniProtKB:Q9NPB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007360 ! CCRL1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0018440 name: CCR10_HUMAN def: "C-C chemokine receptor type 10" [UniProtKB:P46092] synonym: "C-C CKR-10" EXACT [UniProtKB:P46092] synonym: "CC-CKR-10" EXACT [UniProtKB:P46092] synonym: "CCR-10" EXACT [UniProtKB:P46092] synonym: "G-protein coupled receptor 2" EXACT [UniProtKB:P46092] xref: EMBL:AAA64593.1 xref: EMBL:AAF63709.1 xref: EMBL:AAF72871.1 xref: EMBL:AAH98132.1 xref: EMBL:AAH98157.1 xref: EMBL:AAH98304.1 xref: EMBL:AAH99840.1 xref: EMBL:AAR07898.1 xref: UniProtKB:P46092 xref: UniProtKB:Q4V749 xref: UniProtKB:Q6T7X2 xref: UniProtKB:Q9NZG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007359 ! CCR10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018466 ! bat2-gpr2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0064121 ! CCR10_HUMAN-Phosphothreonine295 relationship: transforms_into CCO:B0064122 ! CCR10_HUMAN-Phosphoserine296 [Term] id: CCO:B0018461 name: PIAS3_HUMAN def: "E3 SUMO-protein ligase PIAS3" [UniProtKB:Q9Y6X2] synonym: "Protein inhibitor of activated STAT protein 3" EXACT [UniProtKB:Q9Y6X2] xref: EMBL:AAH01154.1 xref: EMBL:AAH30556.1 xref: EMBL:BAA78533.1 xref: UniProtKB:Q9UFI3 xref: UniProtKB:Q9Y6X2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019397 ! PIAS3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0018465 name: ZN326_HUMAN def: "Zinc finger protein 326" [UniProtKB:Q5BKZ1] xref: EMBL:AAH52645.1 xref: EMBL:AAH53888.1 xref: EMBL:AAH70341.1 xref: EMBL:AAH90866.1 xref: EMBL:CAH72228.1 xref: EMBL:CAH72229.1 xref: EMBL:CAH72230.1 xref: EMBL:CAI23073.1 xref: EMBL:CAI23074.1 xref: UniProtKB:Q5BKZ1 xref: UniProtKB:Q5VW93 xref: UniProtKB:Q5VW94 xref: UniProtKB:Q5VW96 xref: UniProtKB:Q5VW97 xref: UniProtKB:Q6NSA2 xref: UniProtKB:Q7Z638 xref: UniProtKB:Q7Z6C2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020705 ! ZNF326_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072107 ! ZN326_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0072108 ! ZN326_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0072109 ! ZN326_HUMAN-Phosphothreonine274 [Term] id: CCO:B0018469 name: AKP8L_HUMAN def: "A-kinase anchor protein 8-like" [UniProtKB:Q9ULX6] synonym: "AKAP8-like protein" EXACT [UniProtKB:Q9ULX6] synonym: "HA95" EXACT [UniProtKB:Q9ULX6] synonym: "HAP95" EXACT [UniProtKB:Q9ULX6] synonym: "Helicase A-binding protein 95" EXACT [UniProtKB:Q9ULX6] synonym: "Homologous to AKAP95 protein" EXACT [UniProtKB:Q9ULX6] synonym: "Neighbor of A-kinase-anchoring protein 95" EXACT [UniProtKB:Q9ULX6] synonym: "Neighbor of AKAP95" EXACT [UniProtKB:Q9ULX6] xref: EMBL:AAF86048.1 xref: EMBL:AAH00713.1 xref: EMBL:BAA34791.1 xref: EMBL:BAA85003.1 xref: EMBL:CAB65092.1 xref: UniProtKB:O94792 xref: UniProtKB:Q96J58 xref: UniProtKB:Q9NRQ0 xref: UniProtKB:Q9UGM0 xref: UniProtKB:Q9ULX6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007227 ! AKAP8L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016762 ! map3k3-nakap95 physical interaction relationship: transforms_into CCO:B0034529 ! AKP8L_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0065572 ! AKP8L_HUMAN-Phosphothreonine292 relationship: transforms_into CCO:B0065573 ! AKP8L_HUMAN-Phosphothreonine294 relationship: transforms_into CCO:B0065574 ! AKP8L_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0065575 ! AKP8L_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0065576 ! AKP8L_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0065577 ! AKP8L_HUMAN-Phosphothreonine308 [Term] id: CCO:B0018485 name: CLTR2_HUMAN def: "Cysteinyl leukotriene receptor 2" [UniProtKB:Q9NS75] synonym: "CysLTR2" EXACT [UniProtKB:Q9NS75] synonym: "HG57" EXACT [UniProtKB:Q9NS75] synonym: "hGPCR21" EXACT [UniProtKB:Q9NS75] synonym: "HPN321" EXACT [UniProtKB:Q9NS75] xref: EMBL:AAG17281.1 xref: EMBL:AAH69160.1 xref: EMBL:AAK69485.1 xref: EMBL:AAQ91330.1 xref: EMBL:BAB03601.1 xref: EMBL:BAB16379.1 xref: EMBL:BAB89316.1 xref: EMBL:CAC29102.1 xref: UniProtKB:Q9HCQ2 xref: UniProtKB:Q9NS75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017392 ! CYSLTR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000181 ! cysteinyl leukotriene receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001314 ! leukotriene receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0018486 name: CLTR1_HUMAN def: "Cysteinyl leukotriene receptor 1" [UniProtKB:Q9Y271] synonym: "CysLTR1" EXACT [UniProtKB:Q9Y271] synonym: "Cysteinyl leukotriene D4 receptor" EXACT [UniProtKB:Q9Y271] synonym: "HG55" EXACT [UniProtKB:Q9Y271] synonym: "HMTMF81" EXACT [UniProtKB:Q9Y271] synonym: "LTD4 receptor" EXACT [UniProtKB:Q9Y271] xref: EMBL:AAD42285.1 xref: EMBL:AAD42778.1 xref: EMBL:AAH35750.1 xref: EMBL:AAO92297.1 xref: EMBL:CAI40462.1 xref: UniProtKB:Q5JS94 xref: UniProtKB:Q8IV19 xref: UniProtKB:Q9Y271 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017391 ! CYSLTR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001314 ! leukotriene receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0018492 name: Q9Y6S7_HUMAN def: "Putative uncharacterized protein unknown" [UniProtKB:Q9Y6S7] xref: EMBL:AAD30184.1 xref: UniProtKB:Q9Y6S7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0009009 ! unknown_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0018508 name: HXK4_HUMAN def: "Glucokinase" [UniProtKB:P35557] synonym: "EC 2.7.1.2" EXACT [UniProtKB:P35557] synonym: "Hexokinase type IV" EXACT [UniProtKB:P35557] synonym: "Hexokinase-4" EXACT [UniProtKB:P35557] synonym: "Hexokinase-D" EXACT [UniProtKB:P35557] synonym: "HK IV" EXACT [UniProtKB:P35557] synonym: "HK4" EXACT [UniProtKB:P35557] xref: EMBL:AAA51824.1 xref: EMBL:AAA52562.1 xref: EMBL:AAA67541.1 xref: EMBL:AAA67542.1 xref: EMBL:AAB59563.1 xref: EMBL:AAB97680.1 xref: EMBL:AAB97681.1 xref: EMBL:AAB97682.1 xref: EMBL:AAH01890.1 xref: UniProtKB:P35557 xref: UniProtKB:Q05810 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018195 ! GCK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000759 ! glucokinase activity relationship: has_function CCO:F0000807 ! hexokinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001661 ! glucose binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0017890 ! gck-pfkfb1-1 direct interaction relationship: participates_in CCO:I0017891 ! gck-gckr-3 direct interaction relationship: participates_in CCO:I0018074 ! gck-gckr-2 direct interaction relationship: participates_in CCO:I0018075 ! gck-pfkfb1-2 direct interaction relationship: participates_in CCO:P0001532 ! positive regulation of insulin secretion relationship: participates_in CCO:P0002518 ! negative regulation of gluconeogenesis relationship: participates_in CCO:P0002522 ! positive regulation of glycogen biosynthetic process [Term] id: CCO:B0018524 name: HXK1_HUMAN def: "Hexokinase-1" [UniProtKB:P19367] synonym: "Brain form hexokinase" EXACT [UniProtKB:P19367] synonym: "EC 2.7.1.1" EXACT [UniProtKB:P19367] synonym: "Hexokinase type I" EXACT [UniProtKB:P19367] synonym: "HK I" EXACT [UniProtKB:P19367] xref: EMBL:AAA52646.1 xref: EMBL:AAC00172.1 xref: EMBL:AAC15862.1 xref: EMBL:AAC15863.1 xref: EMBL:AAC25424.1 xref: EMBL:AAF82319.1 xref: EMBL:AAF82320.1 xref: EMBL:AAH08730.1 xref: EMBL:CAA47379.1 xref: EMBL:CAH71506.1 xref: UniProtKB:O43443 xref: UniProtKB:O43444 xref: UniProtKB:O75574 xref: UniProtKB:P19367 xref: UniProtKB:Q5VTC3 xref: UniProtKB:Q96HC8 xref: UniProtKB:Q9NNZ4 xref: UniProtKB:Q9NNZ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022324 ! HK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020572 ! hk1-scmh1 physical interaction relationship: transforms_into CCO:B0066966 ! HXK1_HUMAN-Phosphotyrosine27 [Term] id: CCO:B0018532 name: KAPCG_HUMAN def: "cAMP-dependent protein kinase catalytic subunit gamma" [UniProtKB:P22612] synonym: "EC 2.7.11.11" EXACT [UniProtKB:P22612] synonym: "PKA C-gamma" EXACT [UniProtKB:P22612] xref: EMBL:AAC41690.1 xref: EMBL:AAH39888.1 xref: EMBL:ABG25920.1 xref: EMBL:CAA04863.1 xref: EMBL:CAH71828.1 xref: UniProtKB:O60850 xref: UniProtKB:P22612 xref: UniProtKB:Q5VZ02 xref: UniProtKB:Q86YI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007722 ! PRKACG_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001058 ! cAMP-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0034981 ! KAPCG_HUMAN-Phosphothreonine198 relationship: transforms_into CCO:B0034982 ! KAPCG_HUMAN-Phosphoserine339 [Term] id: CCO:B0018534 name: KAPCB_HUMAN def: "cAMP-dependent protein kinase catalytic subunit beta" [UniProtKB:P22694] synonym: "EC 2.7.11.11" EXACT [UniProtKB:P22694] synonym: "PKA C-beta" EXACT [UniProtKB:P22694] xref: EMBL:AAA60170.1 xref: EMBL:AAH35058.1 xref: EMBL:AAN16454.1 xref: EMBL:AAX19487.1 xref: EMBL:AAX19488.1 xref: EMBL:AAX19489.1 xref: EMBL:AAX19490.1 xref: EMBL:AAX19491.1 xref: EMBL:ABG25919.1 xref: EMBL:BAD92426.1 xref: EMBL:CAD97818.1 xref: EMBL:CAE46017.1 xref: EMBL:CAI14541.1 xref: EMBL:CAI16845.1 xref: EMBL:CAI16846.1 xref: EMBL:CAI56774.1 xref: EMBL:EAW73248.1 xref: UniProtKB:P22694 xref: UniProtKB:Q14VH1 xref: UniProtKB:Q59GC0 xref: UniProtKB:Q5BNE9 xref: UniProtKB:Q5BNF0 xref: UniProtKB:Q5BNF1 xref: UniProtKB:Q5BNF2 xref: UniProtKB:Q5BNF3 xref: UniProtKB:Q5CZ92 xref: UniProtKB:Q5T1K3 xref: UniProtKB:Q7Z3M1 xref: UniProtKB:Q8IYR5 xref: UniProtKB:Q8IZQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007721 ! PRKACB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0034977 ! KAPCB_HUMAN-Deamidated asparagine3 relationship: transforms_into CCO:B0034978 ! KAPCB_HUMAN-Phosphotyrosine69 relationship: transforms_into CCO:B0034979 ! KAPCB_HUMAN-Phosphothreonine198 relationship: transforms_into CCO:B0034980 ! KAPCB_HUMAN-Phosphoserine339 [Term] id: CCO:B0018543 name: KAPCA_HUMAN def: "cAMP-dependent protein kinase catalytic subunit alpha" [UniProtKB:P17612] synonym: "EC 2.7.11.11" EXACT [UniProtKB:P17612] synonym: "PKA C-alpha" EXACT [UniProtKB:P17612] xref: EMBL:AAF75622.1 xref: EMBL:AAF76426.1 xref: EMBL:AAG35720.1 xref: EMBL:AAH39846.1 xref: EMBL:AAI08260.1 xref: EMBL:ABG25918.1 xref: EMBL:BAF82836.1 xref: EMBL:CAA30597.1 xref: EMBL:EAW84399.1 xref: UniProtKB:P17612 xref: UniProtKB:Q32P54 xref: UniProtKB:Q9H2Y0 xref: UniProtKB:Q9NRB4 xref: UniProtKB:Q9NRH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007720 ! PRKACA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015903 ! prkaca-prkar1a-1 physical interaction relationship: participates_in CCO:I0017699 ! bca3-prkaca-3 physical interaction relationship: participates_in CCO:I0017700 ! bca3-prkaca-4 physical interaction relationship: participates_in CCO:I0017868 ! bca3-prkaca-1 physical interaction relationship: participates_in CCO:I0018013 ! bca3-prkaca-2 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0034970 ! KAPCA_HUMAN-Deamidated asparagine3 relationship: transforms_into CCO:B0034971 ! KAPCA_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0034972 ! KAPCA_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0034973 ! KAPCA_HUMAN-Phosphothreonine196 relationship: transforms_into CCO:B0034974 ! KAPCA_HUMAN-Phosphothreonine198 relationship: transforms_into CCO:B0034975 ! KAPCA_HUMAN-Phosphothreonine202 relationship: transforms_into CCO:B0034976 ! KAPCA_HUMAN-Phosphoserine339 [Term] id: CCO:B0018552 name: Q4VXV6_HUMAN def: "Wilms tumor 1" [UniProtKB:Q4VXV6] xref: EMBL:CAI95758.2 xref: UniProtKB:Q4VXV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005934 ! WT1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0018555 name: Q4VXV5_HUMAN def: "Wilms tumor 1" [UniProtKB:Q4VXV5] xref: EMBL:CAI95759.2 xref: UniProtKB:Q4VXV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005934 ! WT1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0018582 name: TAF12_HUMAN def: "Transcription initiation factor TFIID subunit 12" [UniProtKB:Q16514] synonym: "TAFII-20/TAFII-15" EXACT [UniProtKB:Q16514] synonym: "TAFII20/TAFII15" EXACT [UniProtKB:Q16514] synonym: "Transcription initiation factor TFIID 20/15 kDa subunits" EXACT [UniProtKB:Q16514] xref: EMBL:AAC50600.1 xref: EMBL:AAC50601.1 xref: EMBL:AAH11986.1 xref: EMBL:AAO13491.1 xref: EMBL:AAP35678.1 xref: EMBL:BAA09112.1 xref: EMBL:CAA58826.1 xref: EMBL:CAI22291.1 xref: UniProtKB:Q15775 xref: UniProtKB:Q16514 xref: UniProtKB:Q5T077 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008260 ! TAF12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017793 ! taf12-taf4-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071085 ! TAF12_HUMAN-Phosphothreonine43 relationship: transforms_into CCO:B0071086 ! TAF12_HUMAN-Phosphoserine51 [Term] id: CCO:B0018655 name: RYK_HUMAN def: "Tyrosine-protein kinase RYK precursor" [UniProtKB:P34925] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P34925] xref: EMBL:AAB26341.1 xref: EMBL:CAA49591.1 xref: EMBL:CAA65406.1 xref: UniProtKB:P34925 xref: UniProtKB:Q04696 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019817 ! RYK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003594 ! Wnt-protein binding relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070271 ! RYK_HUMAN-Phosphotyrosine492 [Term] id: CCO:B0018657 name: MERTK_HUMAN def: "Proto-oncogene tyrosine-protein kinase MER precursor" [UniProtKB:Q12866] synonym: "C-mer" EXACT [UniProtKB:Q12866] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q12866] synonym: "Receptor tyrosine kinase MerTK" EXACT [UniProtKB:Q12866] xref: EMBL:AAB60430.1 xref: EMBL:AAG33129.1 xref: UniProtKB:Q12866 xref: UniProtKB:Q9HBB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018604 ! MERTK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0068148 ! MERTK_HUMAN-Phosphotyrosine754 [Term] id: CCO:B0018660 name: Q15516_HUMAN def: "Tyrosine kinase" [UniProtKB:Q15516] xref: EMBL:AAC41766.1 xref: UniProtKB:Q15516 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0018662 name: Q8IW86_HUMAN def: "TBX18 protein" [UniProtKB:Q8IW86] xref: EMBL:AAH40697.2 xref: UniProtKB:Q8IW86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008278 ! TBX18_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018664 name: TBX22_HUMAN def: "T-box transcription factor TBX22" [UniProtKB:Q9Y458] synonym: "T-box protein 22" EXACT [UniProtKB:Q9Y458] xref: EMBL:AAG23749.1 xref: EMBL:AAH14194.2 xref: EMBL:AAK63189.1 xref: EMBL:CAI43070.1 xref: UniProtKB:Q96LC0 xref: UniProtKB:Q9HBF1 xref: UniProtKB:Q9Y458 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008279 ! TBX22_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018665 name: Q9HA44_HUMAN def: "cDNA FLJ12268 fis, clone MAMMA1001627, highly similar to Homo sapiens transcription factor TBX6" [UniProtKB:Q9HA44] synonym: "T-box 6, isoform CRA_b" EXACT [UniProtKB:Q9HA44] xref: EMBL:BAB14014.1 xref: EMBL:EAW79927.1 xref: UniProtKB:Q9HA44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020199 ! TBX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018667 name: Q5JT54_HUMAN def: "T-box 15" [UniProtKB:Q5JT54] synonym: "cDNA FLJ45629 fis, clone CHONS2000797, highly similar to T-box transcription factor TBX15" EXACT [UniProtKB:Q5JT54] xref: EMBL:AAI22554.2 xref: EMBL:BAG54518.1 xref: EMBL:CAI43068.1 xref: UniProtKB:Q08E76 xref: UniProtKB:Q5JT54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008277 ! TBX15_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018668 name: TBX1_HUMAN def: "T-box transcription factor TBX1" [UniProtKB:O43435] synonym: "T-box protein 1" EXACT [UniProtKB:O43435] synonym: "Testis-specific T-box protein" EXACT [UniProtKB:O43435] xref: EMBL:AAB94018.1 xref: EMBL:AAB94019.1 xref: EMBL:AAK58955.1 xref: UniProtKB:O43435 xref: UniProtKB:O43436 xref: UniProtKB:Q96RJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020194 ! TBX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018669 name: TBX15_HUMAN def: "T-box transcription factor TBX15" [UniProtKB:Q96SF7] synonym: "T-box protein 15" EXACT [UniProtKB:Q96SF7] xref: EMBL:CAI22503.1 xref: EMBL:CAI43066.1 xref: UniProtKB:Q5T9S7 xref: UniProtKB:Q96SF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008277 ! TBX15_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018670 name: TBX6_HUMAN def: "T-box transcription factor TBX6" [UniProtKB:O95947] synonym: "T-box protein 6" EXACT [UniProtKB:O95947] xref: EMBL:AAH26031.1 xref: EMBL:CAA07812.1 xref: EMBL:CAB37938.1 xref: UniProtKB:O95947 xref: UniProtKB:Q8TAS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020199 ! TBX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018671 name: Q5JZ06_HUMAN def: "T-box 22 (T-box 22, isoform CRA_a)" [UniProtKB:Q5JZ06] xref: EMBL:CAI43069.1 xref: EMBL:EAW98588.1 xref: UniProtKB:Q5JZ06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008279 ! TBX22_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018672 name: Q000T4_HUMAN def: "T-box transcription factor TBX20 isoform A" [UniProtKB:Q000T4] xref: EMBL:ABJ15760.1 xref: UniProtKB:Q000T4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020195 ! TBX20_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018676 name: TBX10_HUMAN def: "T-box transcription factor TBX10" [UniProtKB:O75333] synonym: "T-box protein 10" EXACT [UniProtKB:O75333] xref: EMBL:AAC23481.1 xref: EMBL:AAI13486.1 xref: EMBL:AAI13488.1 xref: EMBL:AAO73483.1 xref: UniProtKB:O75333 xref: UniProtKB:Q14D64 xref: UniProtKB:Q86XS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020192 ! TBX10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018677 name: TBX18_HUMAN def: "T-box transcription factor TBX18" [UniProtKB:O95935] synonym: "T-box protein 18" EXACT [UniProtKB:O95935] xref: EMBL:CAB37937.1 xref: EMBL:CAD92511.1 xref: UniProtKB:O95935 xref: UniProtKB:Q7Z6U4 xref: UniProtKB:Q9UJI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008278 ! TBX18_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000525 ! positive regulation of mesenchymal cell proliferation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0018678 name: TBX20_HUMAN def: "T-box transcription factor TBX20" [UniProtKB:Q9UMR3] synonym: "T-box protein 20" EXACT [UniProtKB:Q9UMR3] xref: EMBL:AAD21787.1 xref: EMBL:AAI20946.1 xref: EMBL:AAI20947.1 xref: EMBL:CAB51916.1 xref: UniProtKB:Q0IJ70 xref: UniProtKB:Q0VAS1 xref: UniProtKB:Q9UMR3 xref: UniProtKB:Q9Y2N5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020195 ! TBX20_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0018692 name: Q5W0G9_HUMAN xref: UniProtKB:Q5W0G9 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0018695 name: EDNRA_HUMAN def: "Endothelin-1 receptor precursor" [UniProtKB:P25101] synonym: "Endothelin A receptor" EXACT [UniProtKB:P25101] synonym: "ET-A" EXACT [UniProtKB:P25101] synonym: "ETA-R" EXACT [UniProtKB:P25101] synonym: "hET-AR" EXACT [UniProtKB:P25101] xref: EMBL:AAA58447.1 xref: EMBL:AAB20278.1 xref: EMBL:AAB20407.1 xref: EMBL:AAB23644.1 xref: EMBL:AAB25212.1 xref: EMBL:AAB25530.2 xref: EMBL:AAB36325.1 xref: EMBL:AAB36326.1 xref: EMBL:AAB36327.1 xref: EMBL:AAB94859.1 xref: EMBL:AAH22511.1 xref: EMBL:AAP32294.1 xref: EMBL:AAQ87880.1 xref: EMBL:BAA01920.1 xref: EMBL:BAA14359.1 xref: EMBL:CAA43953.1 xref: UniProtKB:O43441 xref: UniProtKB:P25101 xref: UniProtKB:Q16432 xref: UniProtKB:Q16433 xref: UniProtKB:Q8TBH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007478 ! EDNRA_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000154 ! endothelin-A receptor activity relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001303 ! endothelin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0018697 name: EDNRB_HUMAN def: "Endothelin B receptor precursor" [UniProtKB:P24530] synonym: "Endothelin receptor non-selective type" EXACT [UniProtKB:P24530] synonym: "ET-B" EXACT [UniProtKB:P24530] xref: EMBL:AAA52342.1 xref: EMBL:AAA58465.1 xref: EMBL:AAB19411.1 xref: EMBL:AAB25531.1 xref: EMBL:AAD24541.1 xref: EMBL:AAH14472.1 xref: EMBL:AAP32295.1 xref: EMBL:AAS38516.1 xref: EMBL:BAA02445.1 xref: EMBL:BAA14398.1 xref: EMBL:BAF83388.1 xref: EMBL:CAA67623.1 xref: EMBL:CAD30645.1 xref: EMBL:CAD30646.1 xref: EMBL:CAD30647.1 xref: EMBL:CAD30648.1 xref: EMBL:CAH72430.1 xref: EMBL:CAM16893.1 xref: EMBL:EAW80573.1 xref: EMBL:EAW80575.1 xref: UniProtKB:A2A2Z8 xref: UniProtKB:A8K3T4 xref: UniProtKB:O15343 xref: UniProtKB:P24530 xref: UniProtKB:Q5W0G9 xref: UniProtKB:Q8NHM6 xref: UniProtKB:Q8NHM7 xref: UniProtKB:Q8NHM8 xref: UniProtKB:Q8NHM9 xref: UniProtKB:Q9UQK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007479 ! EDNRB_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000155 ! endothelin-B receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001303 ! endothelin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0018701 name: Q9BUD7_HUMAN def: "ERBB3 protein" [UniProtKB:Q9BUD7] synonym: "V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian)" EXACT [UniProtKB:Q9BUD7] xref: EMBL:AAH02706.1 xref: EMBL:AAP35890.1 xref: UniProtKB:Q9BUD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004578 ! ERBB3_human relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0018717 name: Q9UK79_HUMAN def: "Herstatin" [UniProtKB:Q9UK79] synonym: "V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (Avian), isoform CRA_a" EXACT [UniProtKB:Q9UK79] xref: EMBL:AAD56009.2 xref: EMBL:EAW60595.1 xref: UniProtKB:Q9UK79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008996 ! HER-2_human relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0018759 name: M3KL4_HUMAN def: "Mitogen-activated protein kinase kinase kinase" [UniProtKB:Q5TCX8] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q5TCX8] synonym: "Mixed lineage kinase 4" EXACT [UniProtKB:Q5TCX8] xref: EMBL:BAB47433.1 xref: EMBL:CAC84639.1 xref: EMBL:CAC84640.1 xref: EMBL:CAI23045.1 xref: EMBL:CAI23046.1 xref: EMBL:CAI23047.1 xref: UniProtKB:Q5TCX7 xref: UniProtKB:Q5TCX8 xref: UniProtKB:Q5TCX9 xref: UniProtKB:Q8WWN1 xref: UniProtKB:Q8WWN2 xref: UniProtKB:Q96JM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007809 ! MLK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: transforms_into CCO:B0035156 ! M3KL4_HUMAN-Phosphothreonine299 relationship: transforms_into CCO:B0035157 ! M3KL4_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0035158 ! M3KL4_HUMAN-Phosphoserine547 relationship: transforms_into CCO:B0035159 ! M3KL4_HUMAN-Phosphoserine732 relationship: transforms_into CCO:B0035160 ! M3KL4_HUMAN-Phosphoserine806 relationship: transforms_into CCO:B0067821 ! M3KL4_HUMAN-Phosphoserine614 [Term] id: CCO:B0018761 name: M3K13_HUMAN def: "Mitogen-activated protein kinase kinase kinase 13" [UniProtKB:O43283] synonym: "EC 2.7.11.25" EXACT [UniProtKB:O43283] synonym: "Leucine zipper-bearing kinase" EXACT [UniProtKB:O43283] synonym: "Mixed lineage kinase" EXACT [UniProtKB:O43283] synonym: "MLK" EXACT [UniProtKB:O43283] xref: EMBL:AAH31677.1 xref: EMBL:AAI11727.1 xref: EMBL:BAA24817.1 xref: EMBL:CAA80915.1 xref: UniProtKB:O43283 xref: UniProtKB:Q05BY6 xref: UniProtKB:Q15450 xref: UniProtKB:Q2NKN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007808 ! MAP3K13_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000547 ! IkappaB kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0018123 ! map3k13-mapk13-1 physical interaction relationship: participates_in CCO:I0018124 ! map3k13-mapk13-2 physical interaction relationship: participates_in CCO:P0000410 ! activation of MAPKK activity relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0018770 name: M3K10_HUMAN def: "Mitogen-activated protein kinase kinase kinase 10" [UniProtKB:Q02779] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q02779] synonym: "Mixed lineage kinase 2" EXACT [UniProtKB:Q02779] synonym: "Protein kinase MST" EXACT [UniProtKB:Q02779] xref: EMBL:CAA62351.1 xref: EMBL:CAA88531.1 xref: UniProtKB:Q02779 xref: UniProtKB:Q12761 xref: UniProtKB:Q14871 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007806 ! MAP3K10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: transforms_into CCO:B0035153 ! M3K10_HUMAN-Phosphothreonine258 relationship: transforms_into CCO:B0035154 ! M3K10_HUMAN-Phosphoserine262 relationship: transforms_into CCO:B0035155 ! M3K10_HUMAN-Phosphoserine506 [Term] id: CCO:B0018778 name: M3K12_HUMAN def: "Mitogen-activated protein kinase kinase kinase 12" [UniProtKB:Q12852] synonym: "DLK" EXACT [UniProtKB:Q12852] synonym: "Dual leucine zipper bearing kinase" EXACT [UniProtKB:Q12852] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q12852] synonym: "Leucine-zipper protein kinase" EXACT [UniProtKB:Q12852] synonym: "MAPK-upstream kinase" EXACT [UniProtKB:Q12852] synonym: "Mixed lineage kinase" EXACT [UniProtKB:Q12852] synonym: "MUK" EXACT [UniProtKB:Q12852] synonym: "ZPK" EXACT [UniProtKB:Q12852] xref: EMBL:AAA67343.1 xref: EMBL:AAH50050.1 xref: EMBL:AAL67158.1 xref: UniProtKB:Q12852 xref: UniProtKB:Q86VQ5 xref: UniProtKB:Q8WY25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007807 ! MAP3K12_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0019403 ! c10orf4-map3k12-1 physical interaction relationship: participates_in CCO:I0020320 ! ftl-map3k12 physical interaction relationship: participates_in CCO:I0020435 ! rgs1-map3k12 physical interaction relationship: participates_in CCO:I0020517 ! fra10ac1-map3k12 physical interaction relationship: participates_in CCO:I0020588 ! map3k12-rpl18a physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000772 ! JNK cascade [Term] id: CCO:B0018804 name: Q5T3Y5_HUMAN def: "Doublecortin domain containing 2" [UniProtKB:Q5T3Y5] xref: EMBL:CAI17105.1 xref: UniProtKB:Q5T3Y5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007447 ! DCDC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0018806 name: DCDC2_HUMAN def: "Doublecortin domain-containing protein 2" [UniProtKB:Q9UHG0] synonym: "Protein RU2S" EXACT [UniProtKB:Q9UHG0] xref: EMBL:AAF23610.1 xref: EMBL:AAF23612.1 xref: EMBL:AAH50704.1 xref: EMBL:BAA86468.2 xref: EMBL:CAB61371.1 xref: EMBL:CAH71788.1 xref: EMBL:CAH71789.1 xref: EMBL:CAH73546.1 xref: EMBL:CAI17104.1 xref: UniProtKB:Q5VTR8 xref: UniProtKB:Q5VTR9 xref: UniProtKB:Q86W35 xref: UniProtKB:Q9UFD1 xref: UniProtKB:Q9UHG0 xref: UniProtKB:Q9UHG1 xref: UniProtKB:Q9ULR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007447 ! DCDC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0018807 name: DCD2B_HUMAN def: "Doublecortin domain-containing protein 2B" [UniProtKB:A2VCK2] xref: EMBL:AAI28074.1 xref: UniProtKB:A2VCK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007446 ! DCDC2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0018931 name: Q9P235_HUMAN def: "KIAA1493 protein" [UniProtKB:Q9P235] xref: EMBL:BAA96017.1 xref: UniProtKB:Q9P235 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021273 ! KIAA1493_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0018951 name: ATF6A_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-6 alpha" [UniProtKB:P18850] synonym: "Activating transcription factor 6 alpha" EXACT [UniProtKB:P18850] synonym: "ATF6-alpha" EXACT [UniProtKB:P18850] xref: EMBL:AAB64434.1 xref: EMBL:AAH14969.1 xref: EMBL:AAH71997.1 xref: EMBL:BAA34722.1 xref: EMBL:CAH71144.1 xref: EMBL:CAH73985.1 xref: EMBL:CAH74152.1 xref: UniProtKB:O15139 xref: UniProtKB:P18850 xref: UniProtKB:Q5VW62 xref: UniProtKB:Q6IPB5 xref: UniProtKB:Q9UEC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017094 ! ATF6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018084 ! atf6-hyst1481 physical interaction relationship: participates_in CCO:I0018085 ! atf6-hyst1481-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000688 ! positive regulation of gene-specific transcription involved in unfolded protein response relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0018956 name: RASF3_HUMAN def: "Ras association domain-containing protein 3" [UniProtKB:Q86WH2] xref: EMBL:AAI00950.1 xref: EMBL:AAI00952.1 xref: EMBL:AAO61687.1 xref: EMBL:AAO61688.1 xref: UniProtKB:Q86WH1 xref: UniProtKB:Q86WH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008059 ! RASSF3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0018982 name: SNF8_HUMAN def: "Vacuolar-sorting protein SNF8" [UniProtKB:Q96H20] synonym: "ELL-associated protein of 30 kDa" EXACT [UniProtKB:Q96H20] xref: EMBL:AAD46560.1 xref: EMBL:AAH08976.1 xref: EMBL:AAH38830.1 xref: UniProtKB:Q8IXY3 xref: UniProtKB:Q96H20 xref: UniProtKB:Q9UN50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008192 ! SNF8_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015357 ! snf8-vps25 physical interaction relationship: participates_in CCO:I0015439 ! dvl2-snf8 physical interaction relationship: participates_in CCO:I0015652 ! nif3l1-snf8 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0019045 name: EM55_HUMAN def: "55 kDa erythrocyte membrane protein" [UniProtKB:Q00013] synonym: "Membrane protein, palmitoylated 1" EXACT [UniProtKB:Q00013] synonym: "p55" EXACT [UniProtKB:Q00013] xref: EMBL:AAA60059.1 xref: EMBL:AAA60060.1 xref: EMBL:AAD14835.1 xref: EMBL:AAH02392.1 xref: UniProtKB:Q00013 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017700 ! MPP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015278 ! amotl2-mpp1 physical interaction relationship: participates_in CCO:I0019565 ! atp5c1-mpp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065046 ! EM55_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0065047 ! EM55_HUMAN-Phosphothreonine49 relationship: transforms_into CCO:B0065048 ! EM55_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0065049 ! EM55_HUMAN-Phosphoserine243 [Term] id: CCO:B0019050 name: A6NKB1_HUMAN def: "Putative uncharacterized protein TTN" [UniProtKB:A6NKB1] xref: UniProtKB:A6NKB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005786 ! TTN_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0019065 name: Q495X4_HUMAN def: "RAR-related orphan receptor A" [UniProtKB:Q495X4] synonym: "RAR-related orphan receptor A, isoform CRA_b" EXACT [UniProtKB:Q495X4] xref: EMBL:AAI00988.1 xref: EMBL:AAI00989.1 xref: EMBL:AAI00990.1 xref: EMBL:AAI00991.1 xref: EMBL:EAW77594.1 xref: UniProtKB:Q495X4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008119 ! RORA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0019067 name: RORA_HUMAN def: "Nuclear receptor ROR-alpha" [UniProtKB:P35398] synonym: "Nuclear receptor RZR-alpha" EXACT [UniProtKB:P35398] synonym: "Nuclear receptor subfamily 1 group F member 1" EXACT [UniProtKB:P35398] synonym: "Retinoid-related orphan receptor-alpha" EXACT [UniProtKB:P35398] xref: EMBL:AAA02963.1 xref: EMBL:AAA62658.1 xref: EMBL:AAA62659.1 xref: EMBL:AAA62660.1 xref: EMBL:AAH08831.1 xref: UniProtKB:P35397 xref: UniProtKB:P35398 xref: UniProtKB:P35399 xref: UniProtKB:P45445 xref: UniProtKB:Q96H83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008119 ! RORA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008685 ! psmc5-rora physical interaction relationship: participates_in CCO:I0008763 ! psmc5-rora-1 physical interaction relationship: participates_in CCO:I0016176 ! nr0b1-rora physical interaction relationship: participates_in CCO:I0017583 ! lmo3-rora physical interaction relationship: participates_in CCO:I0017584 ! nr0b1-rora-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0019068 name: RORB_HUMAN def: "Nuclear receptor ROR-beta" [UniProtKB:Q92753] synonym: "Nuclear receptor RZR-beta" EXACT [UniProtKB:Q92753] synonym: "Nuclear receptor subfamily 1 group F member 2" EXACT [UniProtKB:Q92753] synonym: "Retinoid-related orphan receptor-beta" EXACT [UniProtKB:Q92753] xref: EMBL:CAA69929.1 xref: EMBL:CAD13276.2 xref: UniProtKB:Q8WX73 xref: UniProtKB:Q92753 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008120 ! RORB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription [Term] id: CCO:B0019074 name: CNOT6_HUMAN def: "CCR4-NOT transcription complex subunit 6" [UniProtKB:Q9ULM6] synonym: "Carbon catabolite repressor protein 4 homolog" EXACT [UniProtKB:Q9ULM6] synonym: "CCR4 carbon catabolite repression 4-like" EXACT [UniProtKB:Q9ULM6] synonym: "Cytoplasmic deadenylase" EXACT [UniProtKB:Q9ULM6] synonym: "EC 3.1.-.-" EXACT [UniProtKB:Q9ULM6] xref: EMBL:BAA86508.1 xref: UniProtKB:Q9ULM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007404 ! CNOT6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052345 ! CNOT6_HUMAN-Phosphothreonine146 [Term] id: CCO:B0019119 name: CCDC7_HUMAN def: "Coiled-coil domain-containing protein 7" [UniProtKB:Q96M83] xref: EMBL:AAH22020.2 xref: EMBL:AAH42672.1 xref: EMBL:BAB71426.1 xref: UniProtKB:Q8IVQ0 xref: UniProtKB:Q8NEQ0 xref: UniProtKB:Q96M83 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007357 ! CCDC7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015049 ! ccdc7-wdr39 physical interaction relationship: participates_in CCO:I0015555 ! ccdc7-ewsr1 physical interaction [Term] id: CCO:B0019132 name: RHG17_HUMAN def: "Rho GTPase-activating protein 17" [UniProtKB:Q68EM7] synonym: "Rho-type GTPase-activating protein 17" EXACT [UniProtKB:Q68EM7] synonym: "RhoGAP interacting with CIP4 homologs protein 1" EXACT [UniProtKB:Q68EM7] synonym: "RICH-1" EXACT [UniProtKB:Q68EM7] xref: EMBL:AAH01241.1 xref: EMBL:AAH80195.1 xref: EMBL:AAQ13586.1 xref: EMBL:AAQ13632.1 xref: EMBL:BAA91532.1 xref: EMBL:BAB14506.1 xref: EMBL:BAB55203.1 xref: EMBL:BAC86144.1 xref: EMBL:CAC37948.1 xref: EMBL:CAC37949.1 xref: EMBL:CAD38819.1 xref: UniProtKB:Q68EM7 xref: UniProtKB:Q6ZUS4 xref: UniProtKB:Q7Z2F2 xref: UniProtKB:Q8NDG2 xref: UniProtKB:Q96KS2 xref: UniProtKB:Q96KS3 xref: UniProtKB:Q96SS8 xref: UniProtKB:Q9BVF6 xref: UniProtKB:Q9H8U5 xref: UniProtKB:Q9NW54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019719 ! ARHGAP17_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069953 ! RHG17_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0069954 ! RHG17_HUMAN-Phosphoserine575 [Term] id: CCO:B0019134 name: A6NCP5_HUMAN def: "Uncharacterized protein ENSP00000342566 (cDNA FLJ58097, moderately similar to Homo sapiens Rho GTPase activating protein 17 (ARHGAP17), transcript variant 1, mRNA)" [UniProtKB:A6NCP5] xref: EMBL:BAG57745.1 xref: UniProtKB:A6NCP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0019135 name: RICH2_HUMAN def: "Rho GTPase-activating protein RICH2" [UniProtKB:Q17R89] synonym: "NPC-A-10" EXACT [UniProtKB:Q17R89] synonym: "Rho-type GTPase-activating protein RICH2" EXACT [UniProtKB:Q17R89] synonym: "RhoGAP interacting with CIP4 homologs protein 2" EXACT [UniProtKB:Q17R89] synonym: "RICH-2" EXACT [UniProtKB:Q17R89] xref: EMBL:AAI17413.1 xref: EMBL:AAI17417.1 xref: EMBL:AAP73805.1 xref: EMBL:BAA31647.2 xref: UniProtKB:O75160 xref: UniProtKB:Q17R89 xref: UniProtKB:Q7Z5Z7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019742 ! RICH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070017 ! RICH2_HUMAN-Phosphoserine514 [Term] id: CCO:B0019141 name: ASGR1_HUMAN def: "Asialoglycoprotein receptor 1" [UniProtKB:P07306] synonym: "ASGP-R 1" EXACT [UniProtKB:P07306] synonym: "ASGPR 1" EXACT [UniProtKB:P07306] synonym: "Hepatic lectin H1" EXACT [UniProtKB:P07306] xref: EMBL:AAA51785.1 xref: EMBL:AAH32130.1 xref: EMBL:BAB83508.1 xref: UniProtKB:P07306 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022052 ! ASGR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001227 ! asialoglycoprotein receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019193 ! lass2-asgr1 physical interaction relationship: participates_in CCO:I0019332 ! asgr1-lass2 direct interaction [Term] id: CCO:B0019143 name: ASGR2_HUMAN def: "Asialoglycoprotein receptor 2" [UniProtKB:P07307] synonym: "ASGP-R 2" EXACT [UniProtKB:P07307] synonym: "ASGPR 2" EXACT [UniProtKB:P07307] synonym: "Hepatic lectin H2" EXACT [UniProtKB:P07307] xref: EMBL:AAB58308.1 xref: EMBL:AAB59519.1 xref: EMBL:AAH17251.1 xref: EMBL:CAA38997.1 xref: UniProtKB:O00448 xref: UniProtKB:P07307 xref: UniProtKB:Q03969 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017081 ! ASGR2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001227 ! asialoglycoprotein receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019194 ! lass2-asgr2 physical interaction relationship: participates_in CCO:I0019333 ! asgr2-lass2 direct interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0063627 ! ASGR2_HUMAN-Phosphoserine13 [Term] id: CCO:B0019193 name: MYH9_HUMAN def: "Myosin-9" [UniProtKB:P35579] synonym: "Cellular myosin heavy chain, type A" EXACT [UniProtKB:P35579] synonym: "Myosin heavy chain 9" EXACT [UniProtKB:P35579] synonym: "Myosin heavy chain, non-muscle IIa" EXACT [UniProtKB:P35579] synonym: "NMMHC II-a" EXACT [UniProtKB:P35579] synonym: "NMMHC-A" EXACT [UniProtKB:P35579] synonym: "NMMHC-IIA" EXACT [UniProtKB:P35579] synonym: "Non-muscle myosin heavy chain IIa" EXACT [UniProtKB:P35579] synonym: "Non-muscle myosin heavy chain-A" EXACT [UniProtKB:P35579] xref: EMBL:AAA36349.1 xref: EMBL:AAA59888.1 xref: EMBL:AAA61765.1 xref: EMBL:CAB05105.1 xref: EMBL:CAD89954.1 xref: EMBL:CAG30412.1 xref: UniProtKB:O60805 xref: UniProtKB:P35579 xref: UniProtKB:Q86T83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007855 ! MYH9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000788 ! myosin complex relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008564 ! menin-myh9-1 physical interaction relationship: participates_in CCO:I0008567 ! menin-myh9-6 physical interaction relationship: participates_in CCO:I0008576 ! menin-myh9-4 direct interaction relationship: participates_in CCO:I0008577 ! myh9-menin-1 direct interaction relationship: participates_in CCO:I0008579 ! menin-myh9-3 physical interaction relationship: participates_in CCO:I0008581 ! menin-myh9-2 physical interaction relationship: participates_in CCO:I0008582 ! menin-myh9-5 colocalization relationship: participates_in CCO:I0016006 ! myh9-s100p direct interaction relationship: participates_in CCO:I0016205 ! cxcr4-myh9-2 physical interaction relationship: participates_in CCO:I0016206 ! cxcr4-myh9-4 physical interaction relationship: participates_in CCO:I0016441 ! chuk-myh9 physical interaction relationship: participates_in CCO:I0016480 ! ikbke-myh9 physical interaction relationship: participates_in CCO:I0016548 ! ikbkg-myh9 physical interaction relationship: participates_in CCO:I0016742 ! map3k3-myh9 physical interaction relationship: participates_in CCO:I0016914 ! ripk2-myh9 physical interaction relationship: participates_in CCO:I0017025 ! tnfrsf1a-myh9 physical interaction relationship: participates_in CCO:I0017052 ! tnfrsf1b-myh9 physical interaction relationship: participates_in CCO:I0017272 ! nucleolin-myh9-1 physical interaction relationship: participates_in CCO:I0017795 ! cxcr4-myh9-1 physical interaction relationship: participates_in CCO:I0017796 ! ccr5-myh9-1 physical interaction relationship: participates_in CCO:I0017825 ! nucleolin-myh9-2 physical interaction relationship: participates_in CCO:I0017962 ! cxcr4-myh9-3 physical interaction relationship: participates_in CCO:I0017963 ! cxcr4-myh9-5 colocalization relationship: participates_in CCO:I0017965 ! nucleolin-myh9-3 colocalization relationship: participates_in CCO:I0019907 ! ascc2-myh9 physical interaction relationship: participates_in CCO:I0020079 ! myh9-myl9 physical interaction relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0035233 ! MYH9_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: transforms_into CCO:B0035235 ! MYH9_HUMAN-Phosphothreonine638 relationship: transforms_into CCO:B0035236 ! MYH9_HUMAN-Phosphotyrosine754 relationship: transforms_into CCO:B0035237 ! MYH9_HUMAN-Phosphoserine1943 relationship: transforms_into CCO:B0041162 ! MYH9_HUMAN-Phosphoserine1714 relationship: transforms_into CCO:B0068375 ! MYH9_HUMAN-Phosphotyrosine1408 [Term] id: CCO:B0019194 name: MYH10_HUMAN def: "Myosin-10" [UniProtKB:P35580] synonym: "Cellular myosin heavy chain, type B" EXACT [UniProtKB:P35580] synonym: "Myosin heavy chain 10" EXACT [UniProtKB:P35580] synonym: "Myosin heavy chain, non-muscle IIb" EXACT [UniProtKB:P35580] synonym: "NMMHC II-b" EXACT [UniProtKB:P35580] synonym: "NMMHC-B" EXACT [UniProtKB:P35580] synonym: "NMMHC-IIB" EXACT [UniProtKB:P35580] synonym: "Non-muscle myosin heavy chain IIb" EXACT [UniProtKB:P35580] synonym: "Non-muscle myosin heavy chain-B" EXACT [UniProtKB:P35580] xref: EMBL:AAA87712.1 xref: EMBL:AAA99177.1 xref: EMBL:AAB28952.1 xref: EMBL:AAI17692.1 xref: EMBL:EAW90049.1 xref: UniProtKB:P35580 xref: UniProtKB:Q12989 xref: UniProtKB:Q149N3 xref: UniProtKB:Q16087 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006426 ! MYH10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008542 ! chuk-myh10 physical interaction relationship: participates_in CCO:I0008543 ! ikbkb-myh10 physical interaction relationship: participates_in CCO:I0008544 ! ikbke-myh10 physical interaction relationship: participates_in CCO:I0008545 ! ikbkg-myh10 physical interaction relationship: participates_in CCO:I0008546 ! map3k1-myh10 physical interaction relationship: participates_in CCO:I0008547 ! map3k3-myh10 physical interaction relationship: participates_in CCO:I0008548 ! ripk2-myh10 physical interaction relationship: participates_in CCO:I0008550 ! tnfrsf1a-myh10 physical interaction relationship: participates_in CCO:I0008551 ! tnfrsf1b-myh10 physical interaction relationship: participates_in CCO:P0000040 ! cytokinesis after mitosis relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0032851 ! MYH10_HUMAN-Phosphoserine1013 relationship: transforms_into CCO:B0032852 ! MYH10_HUMAN-Phosphoserine1938 relationship: transforms_into CCO:B0032853 ! MYH10_HUMAN-Phosphoserine1952 relationship: transforms_into CCO:B0032854 ! MYH10_HUMAN-Phosphoserine1956 relationship: transforms_into CCO:B0032855 ! MYH10_HUMAN-Phosphothreonine1960 relationship: transforms_into CCO:B0036017 ! MYH10_HUMAN-Phosphothreonine1376 relationship: transforms_into CCO:B0068372 ! MYH10_HUMAN-Phosphotyrosine1415 relationship: transforms_into CCO:B0068373 ! MYH10_HUMAN-Phosphoserine1939 [Term] id: CCO:B0019239 name: Q5FBX3_HUMAN def: "Interferon regulatory factor 1 nirs variant 1" [UniProtKB:Q5FBX3] xref: EMBL:BAD89424.1 xref: UniProtKB:Q5FBX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004903 ! IRF1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0019310 name: S10A4_HUMAN def: "Protein S100-A4" [UniProtKB:P26447] synonym: "Calvasculin" EXACT [UniProtKB:P26447] synonym: "Metastasin" EXACT [UniProtKB:P26447] synonym: "Placental calcium-binding protein" EXACT [UniProtKB:P26447] synonym: "Protein Mts1" EXACT [UniProtKB:P26447] synonym: "S100 calcium-binding protein A4" EXACT [UniProtKB:P26447] xref: EMBL:AAA51920.1 xref: EMBL:AAH00838.1 xref: EMBL:AAH16300.1 xref: EMBL:CAA79474.1 xref: EMBL:CAA83880.1 xref: EMBL:CAG29341.1 xref: EMBL:CAI14754.1 xref: UniProtKB:P26447 xref: UniProtKB:Q6ICP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008146 ! S100A4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015852 ! s100a1-s100a4 physical interaction relationship: participates_in CCO:I0020159 ! s100a4-bat3 physical interaction relationship: participates_in CCO:I0020160 ! s100a4-unc119 physical interaction relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: transforms_into CCO:B0043790 ! S10A4_HUMAN-N-acetylalanine2 [Term] id: CCO:B0019335 name: CATA_HUMAN def: "Catalase" [UniProtKB:P04040] synonym: "EC 1.11.1.6" EXACT [UniProtKB:P04040] xref: EMBL:AAA16651.1 xref: EMBL:AAB59522.1 xref: EMBL:AAI10399.1 xref: EMBL:AAI12218.1 xref: EMBL:AAI12220.1 xref: EMBL:AAK29181.1 xref: EMBL:AAS37679.1 xref: EMBL:BAF84274.1 xref: EMBL:BAG37746.1 xref: EMBL:CAA27717.1 xref: EMBL:CAA27721.1 xref: EMBL:CAB45236.1 xref: EMBL:EAW68170.1 xref: UniProtKB:A8K6C0 xref: UniProtKB:B2RCZ9 xref: UniProtKB:P04040 xref: UniProtKB:Q2M1U4 xref: UniProtKB:Q4VXX5 xref: UniProtKB:Q9BWT9 xref: UniProtKB:Q9UC85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017243 ! CAT_human relationship: has_function CCO:F0000569 ! catalase activity relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003274 ! oxidoreductase activity, acting on peroxide as acceptor relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007987 ! NADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0064085 ! CATA_HUMAN-Phosphotyrosine231 relationship: transforms_into CCO:B0064086 ! CATA_HUMAN-Phosphotyrosine308 relationship: transforms_into CCO:B0064087 ! CATA_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0064088 ! CATA_HUMAN-Phosphoserine517 [Term] id: CCO:B0019340 name: SYGP1_HUMAN def: "Ras GTPase-activating protein SynGAP" [UniProtKB:Q96PV0] synonym: "Neuronal RasGAP" EXACT [UniProtKB:Q96PV0] synonym: "Synaptic Ras GTPase-activating protein 1" EXACT [UniProtKB:Q96PV0] synonym: "Synaptic Ras-GAP 1" EXACT [UniProtKB:Q96PV0] xref: EMBL:BAB67831.2 xref: EMBL:CAA16161.1 xref: EMBL:CAD28452.1 xref: EMBL:CAI18276.2 xref: EMBL:CAM25572.1 xref: EMBL:CAM26304.1 xref: EMBL:CAM26305.1 xref: EMBL:CAM26306.1 xref: UniProtKB:A2AB17 xref: UniProtKB:A2BEL6 xref: UniProtKB:A2BEL7 xref: UniProtKB:A8MQC4 xref: UniProtKB:Q8TCS2 xref: UniProtKB:Q96PV0 xref: UniProtKB:Q9UGE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008256 ! SYNGAP1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0019348 name: A2AB18_HUMAN def: "Synaptic Ras GTPase activating protein 1 homolog (Rat)" [UniProtKB:A2AB18] xref: EMBL:CAM25573.1 xref: EMBL:CAM26307.1 xref: UniProtKB:A2AB18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008256 ! SYNGAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0019350 name: NGAP_HUMAN def: "Ras GTPase-activating protein nGAP" [UniProtKB:Q9UJF2] synonym: "RAS protein activator-like 1" EXACT [UniProtKB:Q9UJF2] xref: EMBL:AAD04814.1 xref: EMBL:CAI21912.1 xref: EMBL:CAI22693.1 xref: UniProtKB:O95174 xref: UniProtKB:Q5TFU9 xref: UniProtKB:Q9UJF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007878 ! RASAL2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0017175 ! nfkbib-rasal2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0035266 ! NGAP_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0068700 ! NGAP_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0068701 ! NGAP_HUMAN-Phosphoserine663 [Term] id: CCO:B0019358 name: RASF6_HUMAN def: "Ras association domain-containing protein 6" [UniProtKB:Q6ZTQ3] xref: EMBL:AAH58835.1 xref: EMBL:AAO61689.1 xref: EMBL:AAO61690.1 xref: EMBL:BAC86530.1 xref: EMBL:CAH18138.1 xref: UniProtKB:Q68DT2 xref: UniProtKB:Q6PDA6 xref: UniProtKB:Q6ZTQ3 xref: UniProtKB:Q86WG9 xref: UniProtKB:Q86WH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008060 ! RASSF6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0019359 name: Q8IZA5_HUMAN def: "RASSF2 protein" [UniProtKB:Q8IZA5] synonym: "Ras association (RalGDS/AF-6) domain family 2 protein isoform 2B" EXACT [UniProtKB:Q8IZA5] xref: EMBL:AAI10386.1 xref: EMBL:AAN59976.1 xref: UniProtKB:Q8IZA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005430 ! RASSF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0019360 name: Q59FL4_HUMAN def: "Ras association domain family 4 isoform a variant" [UniProtKB:Q59FL4] xref: EMBL:BAD92683.1 xref: UniProtKB:Q59FL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0019363 name: TAF5L_HUMAN def: "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L" [UniProtKB:O75529] synonym: "PAF65-beta" EXACT [UniProtKB:O75529] synonym: "PCAF-associated factor 65 beta" EXACT [UniProtKB:O75529] xref: EMBL:AAC39906.1 xref: EMBL:AAH41094.1 xref: EMBL:CAA08816.1 xref: EMBL:CAI22015.1 xref: EMBL:EAW69902.1 xref: UniProtKB:O75529 xref: UniProtKB:Q5TDI6 xref: UniProtKB:Q8IW31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020137 ! TAF5L_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0019365 name: TAF5_HUMAN def: "Transcription initiation factor TFIID subunit 5" [UniProtKB:Q15542] synonym: "TAF(II)100" EXACT [UniProtKB:Q15542] synonym: "TAFII-100" EXACT [UniProtKB:Q15542] synonym: "TAFII100" EXACT [UniProtKB:Q15542] synonym: "Transcription initiation factor TFIID 100 kDa subunit" EXACT [UniProtKB:Q15542] xref: EMBL:AAC50902.1 xref: EMBL:AAC51215.1 xref: EMBL:AAH52268.2 xref: EMBL:BAD97335.1 xref: EMBL:CAA64777.1 xref: EMBL:CAI16747.1 xref: UniProtKB:Q15542 xref: UniProtKB:Q53EM4 xref: UniProtKB:Q5SYD5 xref: UniProtKB:Q86UZ7 xref: UniProtKB:Q9Y4K5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008261 ! TAF5_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0019368 name: PIWL4_HUMAN def: "Piwi-like protein 4" [UniProtKB:Q7Z3Z4] xref: EMBL:AAH31060.1 xref: EMBL:BAC04179.1 xref: EMBL:BAC04873.1 xref: EMBL:BAC81341.1 xref: EMBL:CAH18436.1 xref: UniProtKB:Q68CZ4 xref: UniProtKB:Q7Z3Z4 xref: UniProtKB:Q8N8G9 xref: UniProtKB:Q8N9V8 xref: UniProtKB:Q8NEH2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011613 ! PIWIL4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019362 ! dicer1-eif2c2-4 physical interaction [Term] id: CCO:B0019369 name: PIWL1_HUMAN def: "Piwi-like protein 1" [UniProtKB:Q96J94] xref: EMBL:AAC97371.2 xref: EMBL:AAH28581.1 xref: EMBL:AAK69348.1 xref: EMBL:AAK92281.1 xref: EMBL:BAC04068.1 xref: UniProtKB:O95404 xref: UniProtKB:Q8NA60 xref: UniProtKB:Q8TBY5 xref: UniProtKB:Q96J94 xref: UniProtKB:Q96JD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011611 ! PIWIL1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:B0019383 name: RHG05_HUMAN def: "Rho GTPase-activating protein 5" [UniProtKB:Q13017] synonym: "p190-B" EXACT [UniProtKB:Q13017] synonym: "Rho-type GTPase-activating protein 5" EXACT [UniProtKB:Q13017] xref: EMBL:AAA95963.1 xref: EMBL:AAH32723.1 xref: EMBL:AAH50059.1 xref: EMBL:AAH75799.1 xref: EMBL:AAI29929.1 xref: EMBL:AAI29930.1 xref: EMBL:BAD92988.1 xref: EMBL:BAF85655.1 xref: UniProtKB:A1L375 xref: UniProtKB:A1L376 xref: UniProtKB:A8KAA1 xref: UniProtKB:Q05BE8 xref: UniProtKB:Q05BU8 xref: UniProtKB:Q13017 xref: UniProtKB:Q59ER0 xref: UniProtKB:Q6DHZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011654 ! ARHGAP5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0039619 ! RHG05_HUMAN-Nitrated tyrosine550 relationship: transforms_into CCO:B0069931 ! RHG05_HUMAN-Phosphoserine968 relationship: transforms_into CCO:B0069932 ! RHG05_HUMAN-Phosphoserine1115 relationship: transforms_into CCO:B0069933 ! RHG05_HUMAN-Phosphoserine1124 relationship: transforms_into CCO:B0069934 ! RHG05_HUMAN-Phosphothreonine1129 relationship: transforms_into CCO:B0069935 ! RHG05_HUMAN-Phosphoserine1138 relationship: transforms_into CCO:B0069936 ! RHG05_HUMAN-Phosphoserine1173 relationship: transforms_into CCO:B0069937 ! RHG05_HUMAN-Phosphoserine1176 relationship: transforms_into CCO:B0069938 ! RHG05_HUMAN-Phosphoserine1195 relationship: transforms_into CCO:B0069939 ! RHG05_HUMAN-Phosphoserine1202 relationship: transforms_into CCO:B0069940 ! RHG05_HUMAN-Phosphoserine1218 [Term] id: CCO:B0019407 name: Q6W9G7_HUMAN def: "Histone deacetylase" [UniProtKB:Q6W9G7] synonym: "cDNA FLJ56143, highly similar to Histone deacetylase 7a" EXACT [UniProtKB:Q6W9G7] xref: EMBL:AAQ18232.1 xref: EMBL:BAG61307.1 xref: UniProtKB:Q6W9G7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008805 ! HDAC7_human relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0019411 name: Q6P1W9_HUMAN def: "HDAC7 protein" [UniProtKB:Q6P1W9] synonym: "Histone deacetylase 7A, isoform CRA_f" EXACT [UniProtKB:Q6P1W9] xref: EMBL:AAH64840.1 xref: EMBL:EAW57957.1 xref: UniProtKB:Q6P1W9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008805 ! HDAC7_human relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0019420 name: Q53FN2_HUMAN def: "Cell division cycle protein 23 variant" [UniProtKB:Q53FN2] xref: EMBL:BAD96970.1 xref: UniProtKB:Q53FN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: participates_in CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0019428 name: CPIN1_HUMAN def: "Anamorsin" [UniProtKB:Q6FI81] synonym: "Cytokine-induced apoptosis inhibitor 1" EXACT [UniProtKB:Q6FI81] xref: EMBL:AAC24311.1 xref: EMBL:AAC24312.1 xref: EMBL:AAF71034.1 xref: EMBL:AAG44562.1 xref: EMBL:AAH02568.1 xref: EMBL:AAH24196.1 xref: EMBL:AAH67303.1 xref: EMBL:AAH71740.1 xref: EMBL:CAB66548.1 xref: EMBL:CAG38576.1 xref: UniProtKB:O75206 xref: UniProtKB:O75207 xref: UniProtKB:Q6FI81 xref: UniProtKB:Q9H0W1 xref: UniProtKB:Q9P1L7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011314 ! CIAPIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015605 ! ciapin1-txnl2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0039370 ! CPIN1_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0039371 ! CPIN1_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0039372 ! CPIN1_HUMAN-Phosphoserine185 relationship: transforms_into CCO:B0039373 ! CPIN1_HUMAN-Phosphoserine307 [Term] id: CCO:B0019459 name: UB2D4_HUMAN def: "Ubiquitin-conjugating enzyme E2 D4" [UniProtKB:Q9Y2X8] synonym: "EC 6.3.2.19" EXACT [UniProtKB:Q9Y2X8] synonym: "HBUCE1" EXACT [UniProtKB:Q9Y2X8] synonym: "Ubiquitin carrier protein D4" EXACT [UniProtKB:Q9Y2X8] synonym: "Ubiquitin-protein ligase D4" EXACT [UniProtKB:Q9Y2X8] xref: EMBL:AAD31180.1 xref: EMBL:AAH04104.1 xref: EMBL:BAA91697.1 xref: UniProtKB:Q9Y2X8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008333 ! UBE2D4_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015460 ! dtx2-ube2d4 physical interaction relationship: participates_in CCO:I0019420 ! ube2d4-dtx2 physical interaction [Term] id: CCO:B0019461 name: UB2D3_HUMAN def: "Ubiquitin-conjugating enzyme E2 D3" [UniProtKB:P61077] synonym: "E2(17)KB 3" EXACT [UniProtKB:P61077] synonym: "EC 6.3.2.19" EXACT [UniProtKB:P61077] synonym: "Ubiquitin carrier protein D3" EXACT [UniProtKB:P61077] synonym: "Ubiquitin-conjugating enzyme E2-17 kDa 3" EXACT [UniProtKB:P61077] synonym: "Ubiquitin-protein ligase D3" EXACT [UniProtKB:P61077] xref: EMBL:AAA91461.1 xref: EMBL:AAF35234.1 xref: EMBL:AAH03395.1 xref: EMBL:AAH37894.1 xref: EMBL:AAH66917.1 xref: EMBL:CAG33197.1 xref: EMBL:EAX06138.1 xref: UniProtKB:A6NM99 xref: UniProtKB:P47986 xref: UniProtKB:P61077 xref: UniProtKB:Q6IB88 xref: UniProtKB:Q6NXS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008332 ! UBE2D3_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015648 ! trim39-ube2d3 physical interaction relationship: participates_in CCO:I0015738 ! rnf126-ube2d3 physical interaction relationship: participates_in CCO:I0018446 ! hsrma1-ube2d3 physical interaction relationship: participates_in CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:B0019462 name: UB2D1_HUMAN def: "Ubiquitin-conjugating enzyme E2 D1" [UniProtKB:P51668] synonym: "E2(17)KB 1" EXACT [UniProtKB:P51668] synonym: "EC 6.3.2.19" EXACT [UniProtKB:P51668] synonym: "SFT" EXACT [UniProtKB:P51668] synonym: "Stimulator of Fe transport" EXACT [UniProtKB:P51668] synonym: "UBC4/5 homolog" EXACT [UniProtKB:P51668] synonym: "UbcH5" EXACT [UniProtKB:P51668] synonym: "Ubiquitin carrier protein D1" EXACT [UniProtKB:P51668] synonym: "Ubiquitin-conjugating enzyme E2-17 kDa 1" EXACT [UniProtKB:P51668] synonym: "Ubiquitin-protein ligase D1" EXACT [UniProtKB:P51668] xref: EMBL:AAH05980.1 xref: EMBL:AAH15997.1 xref: EMBL:AAM81086.1 xref: EMBL:AAP35690.1 xref: EMBL:CAA55019.1 xref: EMBL:CAC82097.1 xref: EMBL:CAC82177.1 xref: UniProtKB:P51668 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008330 ! UBE2D1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008676 ! trim39-ube2d1 physical interaction relationship: participates_in CCO:I0008682 ! rnf126-ube2d1 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001432 ! positive regulation of protein ubiquitination [Term] id: CCO:B0019498 name: SCND1_HUMAN def: "SCAN domain-containing protein 1" [UniProtKB:P57086] xref: EMBL:AAF59839.1 xref: EMBL:AAH00785.1 xref: EMBL:AAH36709.1 xref: EMBL:AAH41022.1 xref: EMBL:CAC09390.1 xref: UniProtKB:P57086 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008166 ! SCAND1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015209 ! q96fa9-scand1 physical interaction relationship: participates_in CCO:I0015448 ! scand1-znf434 physical interaction relationship: participates_in CCO:I0015544 ! scand1-znf167 physical interaction relationship: participates_in CCO:I0015547 ! scand1-znf263 physical interaction relationship: participates_in CCO:I0015638 ! scand1-znf165 physical interaction relationship: participates_in CCO:I0015723 ! scand1-znf24 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0019510 name: TAOK3_HUMAN def: "Serine/threonine-protein kinase TAO3" [UniProtKB:Q9H2K8] synonym: "CTCL tumor antigen HD-CL-09" EXACT [UniProtKB:Q9H2K8] synonym: "Cutaneous T-cell lymphoma tumor antigen HD-CL-09" EXACT [UniProtKB:Q9H2K8] synonym: "Dendritic cell-derived protein kinase" EXACT [UniProtKB:Q9H2K8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9H2K8] synonym: "hKFC-A" EXACT [UniProtKB:Q9H2K8] synonym: "JNK/SAPK-inhibitory kinase" EXACT [UniProtKB:Q9H2K8] synonym: "Jun kinase-inhibitory kinase" EXACT [UniProtKB:Q9H2K8] synonym: "Kinase from chicken homolog A" EXACT [UniProtKB:Q9H2K8] synonym: "Thousand and one amino acid protein 3" EXACT [UniProtKB:Q9H2K8] xref: EMBL:AAF14559.1 xref: EMBL:AAF25817.1 xref: EMBL:AAG09131.1 xref: EMBL:AAG38501.1 xref: EMBL:AAH02756.1 xref: EMBL:AAN09723.1 xref: EMBL:AAP35849.1 xref: EMBL:CAH56239.1 xref: UniProtKB:Q658N1 xref: UniProtKB:Q8IUM4 xref: UniProtKB:Q9H2K8 xref: UniProtKB:Q9HC79 xref: UniProtKB:Q9NZM9 xref: UniProtKB:Q9UHG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020147 ! TAOK3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0002690 ! negative regulation of JNK cascade relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: transforms_into CCO:B0071124 ! TAOK3_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0071125 ! TAOK3_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0071126 ! TAOK3_HUMAN-Phosphoserine346 relationship: transforms_into CCO:B0071127 ! TAOK3_HUMAN-Phosphoserine349 relationship: transforms_into CCO:B0071128 ! TAOK3_HUMAN-Phosphoserine442 [Term] id: CCO:B0019513 name: TAOK2_HUMAN def: "Serine/threonine-protein kinase TAO2" [UniProtKB:Q9UL54] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UL54] synonym: "hKFC-C" EXACT [UniProtKB:Q9UL54] synonym: "Kinase from chicken homolog C" EXACT [UniProtKB:Q9UL54] synonym: "Prostate-derived STE20-like kinase 1" EXACT [UniProtKB:Q9UL54] synonym: "PSK-1" EXACT [UniProtKB:Q9UL54] synonym: "Thousand and one amino acid protein 2" EXACT [UniProtKB:Q9UL54] xref: EMBL:AAD45616.1 xref: EMBL:AAG38503.1 xref: EMBL:AAQ89301.1 xref: EMBL:BAA74904.2 xref: EMBL:CAB70882.1 xref: UniProtKB:O94957 xref: UniProtKB:Q6UW73 xref: UniProtKB:Q7LC09 xref: UniProtKB:Q9NSW2 xref: UniProtKB:Q9UL54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020146 ! TAOK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000410 ! activation of MAPKK activity relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: transforms_into CCO:B0071122 ! TAOK2_HUMAN-Phosphotyrosine43 relationship: transforms_into CCO:B0071123 ! TAOK2_HUMAN-Phosphoserine181 [Term] id: CCO:B0019541 name: TMPS6_HUMAN def: "Transmembrane protease, serine 6" [UniProtKB:Q8IU80] synonym: "EC 3.4.21.-" EXACT [UniProtKB:Q8IU80] synonym: "Matriptase-2" EXACT [UniProtKB:Q8IU80] xref: EMBL:AAH39082.1 xref: EMBL:AAL16413.1 xref: EMBL:AAL16414.1 xref: EMBL:AAQ88764.1 xref: EMBL:CAC85953.1 xref: EMBL:CAG30332.1 xref: EMBL:CAQ07360.1 xref: EMBL:CAQ07361.1 xref: EMBL:CAQ07363.1 xref: EMBL:CAQ07364.1 xref: UniProtKB:B0QYB4 xref: UniProtKB:B0QYB7 xref: UniProtKB:B0QYB8 xref: UniProtKB:Q5TI06 xref: UniProtKB:Q6ICC2 xref: UniProtKB:Q6UXD8 xref: UniProtKB:Q8IU80 xref: UniProtKB:Q8IUE2 xref: UniProtKB:Q8IXV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008312 ! TMPRSS6_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0019585 name: PLST_HUMAN def: "Plastin-3" [UniProtKB:P13797] synonym: "T-plastin" EXACT [UniProtKB:P13797] xref: EMBL:AAA36759.1 xref: EMBL:AAA61214.1 xref: EMBL:AAB02844.1 xref: EMBL:AAH39049.1 xref: EMBL:AAH56898.1 xref: EMBL:CAI39884.1 xref: UniProtKB:B1AQ09 xref: UniProtKB:P13797 xref: UniProtKB:Q86YI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007989 ! PLS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017379 ! tcp1-atx2-4 physical interaction relationship: participates_in CCO:I0018333 ! tcp1-atx2-1 physical interaction relationship: participates_in CCO:I0019395 ! tcp1-atx2-3 physical interaction relationship: transforms_into CCO:B0035401 ! PLST_HUMAN-Phosphothreonine114 relationship: transforms_into CCO:B0039592 ! PLST_HUMAN-Phosphoserine474 relationship: transforms_into CCO:B0039593 ! PLST_HUMAN-Phosphothreonine489 [Term] id: CCO:B0019594 name: PLSL_HUMAN def: "Plastin-2" [UniProtKB:P13796] synonym: "L-plastin" EXACT [UniProtKB:P13796] synonym: "LC64P" EXACT [UniProtKB:P13796] synonym: "LCP-1" EXACT [UniProtKB:P13796] synonym: "Lymphocyte cytosolic protein 1" EXACT [UniProtKB:P13796] xref: EMBL:AAA36184.1 xref: EMBL:AAA59529.1 xref: EMBL:AAA63236.1 xref: EMBL:AAB02845.1 xref: EMBL:AAH07673.1 xref: EMBL:AAH10271.1 xref: UniProtKB:P13796 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007988 ! LCP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017380 ! lcp1-atx2-3 physical interaction relationship: participates_in CCO:I0018332 ! lcp1-atx2 physical interaction relationship: participates_in CCO:I0019396 ! lcp1-atx2-2 physical interaction relationship: transforms_into CCO:B0035397 ! PLSL_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035398 ! PLSL_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0035399 ! PLSL_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0035400 ! PLSL_HUMAN-Phosphotyrosine124 relationship: transforms_into CCO:B0069419 ! PLSL_HUMAN-Phosphotyrosine28 relationship: transforms_into CCO:B0069420 ! PLSL_HUMAN-Phosphotyrosine276 [Term] id: CCO:B0019601 name: CK016_HUMAN def: "Uncharacterized protein C11orf16" [UniProtKB:Q9NQ32] xref: EMBL:AAH27865.1 xref: EMBL:CAB92289.1 xref: UniProtKB:Q8N6Y9 xref: UniProtKB:Q9NQ32 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022128 ! C11orf16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015230 ! c11orf16-ewsr1 physical interaction [Term] id: CCO:B0019606 name: BUD31_HUMAN def: "Protein BUD31 homolog" [UniProtKB:P41223] synonym: "EDG-2" EXACT [UniProtKB:P41223] synonym: "Protein G10 homolog" EXACT [UniProtKB:P41223] xref: EMBL:AAA20008.1 xref: EMBL:AAB33291.1 xref: EMBL:AAH22821.1 xref: EMBL:AAI04671.1 xref: EMBL:CAG33232.1 xref: UniProtKB:P41223 xref: UniProtKB:Q6IB53 xref: UniProtKB:Q9UDV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007322 ! BUD31_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0019651 name: ATS8_HUMAN def: "A disintegrin and metalloproteinase with thrombospondin motifs 8 precursor" [UniProtKB:Q9UP79] synonym: "ADAM-TS 8" EXACT [UniProtKB:Q9UP79] synonym: "ADAM-TS8" EXACT [UniProtKB:Q9UP79] synonym: "ADAMTS-8" EXACT [UniProtKB:Q9UP79] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q9UP79] synonym: "METH-2" EXACT [UniProtKB:Q9UP79] synonym: "METH-8" EXACT [UniProtKB:Q9UP79] xref: EMBL:AAD48081.1 xref: EMBL:AAF25806.1 xref: UniProtKB:Q9NZS0 xref: UniProtKB:Q9UP79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007294 ! ADAMTS8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0034581 ! ATS8_HUMAN-Phosphotyrosine255 relationship: transforms_into CCO:B0034582 ! ATS8_HUMAN-Phosphoserine259 [Term] id: CCO:B0019657 name: ATL4_HUMAN def: "ADAMTS-like protein 4 precursor" [UniProtKB:Q6UY14] synonym: "ADAMTSL-4" EXACT [UniProtKB:Q6UY14] synonym: "Thrombospondin repeat-containing protein 1" EXACT [UniProtKB:Q6UY14] xref: EMBL:AAG17217.1 xref: EMBL:AAH27478.1 xref: EMBL:AAH71852.1 xref: EMBL:AAH94811.1 xref: EMBL:AAQ88489.1 xref: EMBL:CAI15499.1 xref: EMBL:CAI15500.2 xref: UniProtKB:Q5T5F7 xref: UniProtKB:Q6IPM6 xref: UniProtKB:Q6UY14 xref: UniProtKB:Q8N643 xref: UniProtKB:Q9HBS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017098 ! ADAMTSL4_human relationship: has_function CCO:F0000256 ! protease binding relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0019660 name: Q59FG3_HUMAN def: "A disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein variant" [UniProtKB:Q59FG3] xref: EMBL:BAD92734.1 xref: UniProtKB:Q59FG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0019689 name: ATS1_HUMAN def: "A disintegrin and metalloproteinase with thrombospondin motifs 1 precursor" [UniProtKB:Q9UHI8] synonym: "ADAM-TS 1" EXACT [UniProtKB:Q9UHI8] synonym: "ADAM-TS1" EXACT [UniProtKB:Q9UHI8] synonym: "ADAMTS-1" EXACT [UniProtKB:Q9UHI8] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q9UHI8] synonym: "METH-1" EXACT [UniProtKB:Q9UHI8] xref: EMBL:AAD48080.1 xref: EMBL:AAF15317.1 xref: EMBL:AAF23772.1 xref: EMBL:BAA92584.1 xref: EMBL:BAA95502.1 xref: EMBL:CAB82413.1 xref: UniProtKB:Q9NSJ8 xref: UniProtKB:Q9P2K0 xref: UniProtKB:Q9UH83 xref: UniProtKB:Q9UHI8 xref: UniProtKB:Q9UP80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007286 ! ADAMTS1_human relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0019703 name: Q59FE5_HUMAN def: "A disintegrin-like and metalloprotease (Reprolysin type) with thrombospondin type 1 motif, 10 preproprotein variant" [UniProtKB:Q59FE5] xref: EMBL:BAD92752.1 xref: UniProtKB:Q59FE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0019767 name: WDHD1_HUMAN def: "WD repeat and HMG-box DNA-binding protein 1" [UniProtKB:O75717] synonym: "Acidic nucleoplasmic DNA-binding protein 1" EXACT [UniProtKB:O75717] synonym: "And-1" EXACT [UniProtKB:O75717] xref: EMBL:AAH00622.1 xref: EMBL:AAH43349.1 xref: EMBL:AAH63041.1 xref: EMBL:CAA06932.1 xref: UniProtKB:O75717 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008352 ! WDHD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035829 ! WDHD1_HUMAN-Phosphoserine374 relationship: transforms_into CCO:B0035830 ! WDHD1_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0035831 ! WDHD1_HUMAN-Phosphothreonine826 relationship: transforms_into CCO:B0035832 ! WDHD1_HUMAN-Phosphoserine868 relationship: transforms_into CCO:B0035833 ! WDHD1_HUMAN-Phosphoserine1041 [Term] id: CCO:B0019772 name: EPS8_HUMAN def: "Epidermal growth factor receptor kinase substrate 8" [UniProtKB:Q12929] xref: EMBL:AAA62280.1 xref: EMBL:AAH30010.1 xref: EMBL:EAW96354.1 xref: UniProtKB:A6NMC3 xref: UniProtKB:Q12929 xref: UniProtKB:Q8N6J0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017723 ! EPS8_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015017 ! eps8-pldn physical interaction relationship: participates_in CCO:I0015709 ! eps8-hook2 physical interaction relationship: participates_in CCO:I0015802 ! cxorf2-eps8 physical interaction relationship: participates_in CCO:I0015834 ! baiap2-eps8 physical interaction relationship: participates_in CCO:I0015838 ! eps8-eps8 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:I0019991 ! eps8-mrpl20 physical interaction relationship: participates_in CCO:I0019992 ! eps8-myo15a physical interaction relationship: participates_in CCO:I0020305 ! eps8-dnali1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0065099 ! EPS8_HUMAN-Phosphotyrosine525 relationship: transforms_into CCO:B0065100 ! EPS8_HUMAN-Phosphotyrosine774 relationship: transforms_into CCO:B0065101 ! EPS8_HUMAN-Phosphoserine811 relationship: transforms_into CCO:B0065102 ! EPS8_HUMAN-Phosphoserine815 [Term] id: CCO:B0019813 name: A6NMQ1_HUMAN def: "DNA polymerase" [UniProtKB:A6NMQ1] synonym: "EC 2.7.7.7" EXACT [UniProtKB:A6NMQ1] xref: UniProtKB:A6NMQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004509 ! POLA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0019877 name: Q7KZS6_HUMAN def: "Tubulin, beta, 4" [UniProtKB:Q7KZS6] synonym: "HCG2042771" EXACT [UniProtKB:Q7KZS6] xref: EMBL:AAP35617.1 xref: EMBL:EAW66675.1 xref: UniProtKB:Q7KZS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008823 ! hCG_2042771_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_function CCO:F0001318 ! melanocyte stimulating hormone receptor activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0019878 name: TBB2C_HUMAN def: "Tubulin beta-2C chain" [UniProtKB:P68371] synonym: "Tubulin beta-2 chain" EXACT [UniProtKB:P68371] xref: EMBL:AAH01911.1 xref: EMBL:AAH02783.1 xref: EMBL:AAH02885.1 xref: EMBL:AAH04188.1 xref: EMBL:AAH07889.1 xref: EMBL:AAH12835.1 xref: EMBL:AAH19359.1 xref: EMBL:AAH19829.1 xref: EMBL:AAH39175.1 xref: EMBL:AAH71889.1 xref: EMBL:CAA26203.1 xref: UniProtKB:P05217 xref: UniProtKB:P68371 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008271 ! TUBB2C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0002050 ! natural killer cell mediated cytotoxicity relationship: transforms_into CCO:B0035757 ! TBB2C_HUMAN-Phosphotyrosine51 relationship: transforms_into CCO:B0035758 ! TBB2C_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0071208 ! TBB2C_HUMAN-Phosphoserine322 [Term] id: CCO:B0019883 name: TBB6_HUMAN def: "Tubulin beta-6 chain" [UniProtKB:Q9BUF5] xref: EMBL:AAH02654.1 xref: EMBL:BAB14016.1 xref: UniProtKB:Q9BUF5 xref: UniProtKB:Q9HA42 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008273 ! TUBB6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016630 ! map3k1-q9buf5 physical interaction relationship: participates_in CCO:I0016722 ! map3k3-q9buf5 physical interaction relationship: participates_in CCO:I0016810 ! nfkb2-q9buf5 physical interaction relationship: participates_in CCO:I0017018 ! tnfrsf1a-q9buf5 physical interaction relationship: participates_in CCO:I0017146 ! traf6-q9buf5 physical interaction relationship: transforms_into CCO:B0035759 ! TBB6_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0035760 ! TBB6_HUMAN-Phosphotyrosine106 [Term] id: CCO:B0019928 name: EIF1_HUMAN def: "Eukaryotic translation initiation factor 1" [UniProtKB:P41567] synonym: "A121" EXACT [UniProtKB:P41567] synonym: "eIF1" EXACT [UniProtKB:P41567] synonym: "Protein translation factor SUI1 homolog" EXACT [UniProtKB:P41567] synonym: "Sui1iso1" EXACT [UniProtKB:P41567] xref: EMBL:AAA60602.1 xref: EMBL:AAD19900.1 xref: EMBL:AAD52028.1 xref: EMBL:AAH05118.1 xref: EMBL:AAH08710.1 xref: UniProtKB:P41567 xref: UniProtKB:Q9UNQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017676 ! EIF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020615 ! olfm2-sui1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0064947 ! EIF1_HUMAN-Phosphotyrosine30 [Term] id: CCO:B0019930 name: EIF1B_HUMAN def: "Eukaryotic translation initiation factor 1b" [UniProtKB:O60739] synonym: "eIF1b" EXACT [UniProtKB:O60739] synonym: "Protein translation factor SUI1 homolog GC20" EXACT [UniProtKB:O60739] xref: EMBL:AAC17112.1 xref: EMBL:AAD27785.1 xref: EMBL:AAF79182.1 xref: EMBL:AAH06996.1 xref: UniProtKB:O60739 xref: UniProtKB:Q9UQF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017675 ! EIF1B_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000661 ! regulation of translational initiation [Term] id: CCO:B0019963 name: TISD_HUMAN def: "Butyrate response factor 2" [UniProtKB:P47974] synonym: "EGF-response factor 2" EXACT [UniProtKB:P47974] synonym: "ERF-2" EXACT [UniProtKB:P47974] synonym: "Protein TIS11D" EXACT [UniProtKB:P47974] xref: EMBL:AAA91778.1 xref: EMBL:AAH05010.1 xref: EMBL:CAA55592.1 xref: UniProtKB:P47974 xref: UniProtKB:Q9BSJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020277 ! ZFP36L2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0019991 name: A2ABL4_HUMAN def: "Discoidin domain receptor family, member 1" [UniProtKB:A2ABL4] xref: EMBL:CAM24839.1 xref: EMBL:CAM25688.1 xref: EMBL:CAQ06759.1 xref: EMBL:CAQ09770.1 xref: UniProtKB:A2ABL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004453 ! DDR1_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0019996 name: Q9H836_HUMAN def: "cDNA FLJ13963 fis, clone Y79AA1001299, highly similar to Homo sapiens integrase interactor 1b protein (INI1B)" [UniProtKB:Q9H836] xref: EMBL:BAB14784.1 xref: UniProtKB:Q9H836 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: participates_in CCO:I0017253 ! relb-q9h836 physical interaction [Term] id: CCO:B0020040 name: A3RLL6_HUMAN def: "Cellular apoptosis susceptibility protein variant 2" [UniProtKB:A3RLL6] xref: EMBL:ABO15009.1 xref: UniProtKB:A3RLL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008407 ! CSE1L-2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001803 ! importin-alpha export receptor activity relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0020052 name: CHIC2_HUMAN def: "Cysteine-rich hydrophobic domain 2 protein" [UniProtKB:Q9UKJ5] synonym: "BrX-like translocated in leukemia" EXACT [UniProtKB:Q9UKJ5] xref: EMBL:AAD55981.1 xref: EMBL:AAH34691.1 xref: UniProtKB:Q9UKJ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007389 ! CHIC2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000379 ! Golgi-associated vesicle relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0015006 ! chic2-top3b physical interaction relationship: participates_in CCO:I0015079 ! chic2-mdfi physical interaction relationship: participates_in CCO:I0015269 ! chic2-hoxa1 physical interaction relationship: participates_in CCO:I0015751 ! chic2-otx1 physical interaction [Term] id: CCO:B0020068 name: PDIA2_HUMAN def: "Protein disulfide-isomerase A2 precursor" [UniProtKB:Q13087] synonym: "EC 5.3.4.1" EXACT [UniProtKB:Q13087] synonym: "PDIp" EXACT [UniProtKB:Q13087] xref: EMBL:AAC50401.1 xref: EMBL:AAH00537.2 xref: EMBL:AAK61223.1 xref: UniProtKB:Q13087 xref: UniProtKB:Q96KJ6 xref: UniProtKB:Q9BW95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019349 ! PDIA2_human relationship: has_function CCO:F0000320 ! protein disulfide isomerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: participates_in CCO:P0000839 ! apoptotic program [Term] id: CCO:B0020080 name: ACTN3_HUMAN def: "Alpha-actinin-3" [UniProtKB:Q08043] synonym: "Alpha-actinin skeletal muscle isoform 3" EXACT [UniProtKB:Q08043] synonym: "F-actin cross-linking protein" EXACT [UniProtKB:Q08043] xref: EMBL:AAA51585.1 xref: EMBL:AAH99647.1 xref: EMBL:AAH99649.1 xref: UniProtKB:A6NP77 xref: UniProtKB:Q08043 xref: UniProtKB:Q4KKV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007209 ! ACTN3_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0001136 ! pseudopodium relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0020112 name: FCN2_HUMAN def: "Ficolin-2 precursor" [UniProtKB:Q15485] synonym: "37 kDa elastin-binding protein" EXACT [UniProtKB:Q15485] synonym: "Collagen/fibrinogen domain-containing protein 2" EXACT [UniProtKB:Q15485] synonym: "EBP-37" EXACT [UniProtKB:Q15485] synonym: "Ficolin-B" EXACT [UniProtKB:Q15485] synonym: "Ficolin-beta" EXACT [UniProtKB:Q15485] synonym: "Hucolin" EXACT [UniProtKB:Q15485] synonym: "L-ficolin" EXACT [UniProtKB:Q15485] synonym: "Serum lectin p35" EXACT [UniProtKB:Q15485] xref: EMBL:AAH69572.1 xref: EMBL:AAH69825.1 xref: EMBL:ABB01005.1 xref: EMBL:BAA08352.1 xref: EMBL:BAA09636.1 xref: EMBL:CAI39861.1 xref: EMBL:EAW88133.1 xref: EMBL:EAW88135.1 xref: UniProtKB:A6NFG7 xref: UniProtKB:Q15485 xref: UniProtKB:Q6IS69 xref: UniProtKB:Q7M4P4 xref: UniProtKB:Q9UC57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017771 ! FCN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066153 ! FCN2_HUMAN-Hydroxyproline77 relationship: transforms_into CCO:B0066154 ! FCN2_HUMAN-Hydroxyproline80 relationship: transforms_into CCO:B0066155 ! FCN2_HUMAN-Hydroxyproline86 [Term] id: CCO:B0020113 name: FBCD1_HUMAN def: "Fibrinogen C domain-containing protein 1" [UniProtKB:Q8N539] xref: EMBL:AAH32953.1 xref: EMBL:AAQ88678.1 xref: EMBL:BAB55319.1 xref: EMBL:CAM45760.1 xref: EMBL:CAM45761.1 xref: UniProtKB:A3KFK0 xref: UniProtKB:Q6UXK6 xref: UniProtKB:Q8N539 xref: UniProtKB:Q96SJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017766 ! FIBCD1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020115 name: ANGL5_HUMAN def: "Angiopoietin-related protein 5 precursor" [UniProtKB:Q86XS5] synonym: "Angiopoietin-like 5" EXACT [UniProtKB:Q86XS5] xref: EMBL:AAH49170.1 xref: EMBL:AAO38749.1 xref: EMBL:AAQ89186.1 xref: UniProtKB:Q86VR9 xref: UniProtKB:Q86XS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016969 ! ANGPTL5_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020117 name: Q92531_HUMAN def: "P35-related protein" [UniProtKB:Q92531] xref: EMBL:BAA09707.1 xref: UniProtKB:Q92531 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017770 ! FCN1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020119 name: Q68DD1_HUMAN def: "Putative uncharacterized protein DKFZp781B1032" [UniProtKB:Q68DD1] xref: EMBL:CAH18289.1 xref: UniProtKB:Q68DD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021159 ! DKFZp781B1032_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020121 name: A3KFJ8_HUMAN def: "Fibrinogen C domain containing 1" [UniProtKB:A3KFJ8] xref: EMBL:CAM45759.1 xref: UniProtKB:A3KFJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017766 ! FIBCD1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020122 name: FCN1_HUMAN def: "Ficolin-1 precursor" [UniProtKB:O00602] synonym: "Collagen/fibrinogen domain-containing protein 1" EXACT [UniProtKB:O00602] synonym: "Ficolin-A" EXACT [UniProtKB:O00602] synonym: "Ficolin-alpha" EXACT [UniProtKB:O00602] synonym: "M-ficolin" EXACT [UniProtKB:O00602] xref: EMBL:AAB50706.1 xref: EMBL:AAH20635.1 xref: EMBL:BAA12120.1 xref: UniProtKB:O00602 xref: UniProtKB:Q92596 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017770 ! FCN1_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020123 name: MFAP4_HUMAN def: "Microfibril-associated glycoprotein 4 precursor" [UniProtKB:P55083] xref: EMBL:AAB00968.1 xref: EMBL:AAH62415.1 xref: UniProtKB:P55083 xref: UniProtKB:Q6P680 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018609 ! MFAP4_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000169 ! microfibril relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020161 name: TALDO_HUMAN def: "Transaldolase" [UniProtKB:P37837] synonym: "EC 2.2.1.2" EXACT [UniProtKB:P37837] xref: EMBL:AAB53943.1 xref: EMBL:AAC52068.1 xref: EMBL:AAF40478.1 xref: EMBL:AAH10103.1 xref: EMBL:AAH18847.2 xref: UniProtKB:O00751 xref: UniProtKB:P37837 xref: UniProtKB:Q8WV32 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011705 ! TALDO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016101 ! taldo1-zhx1 physical interaction relationship: transforms_into CCO:B0039669 ! TALDO_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0039670 ! TALDO_HUMAN-Phosphoserine237 [Term] id: CCO:B0020193 name: SL9A2_HUMAN def: "Sodium/hydrogen exchanger 2" [UniProtKB:Q9UBY0] synonym: "Na(+)/H(+) exchanger 2" EXACT [UniProtKB:Q9UBY0] synonym: "NHE-2" EXACT [UniProtKB:Q9UBY0] synonym: "Solute carrier family 9 member 2" EXACT [UniProtKB:Q9UBY0] xref: EMBL:AAD41635.1 xref: EMBL:AAF19248.1 xref: UniProtKB:Q9UBY0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013634 ! SLC9A2_human relationship: has_function CCO:F0002746 ! antiporter activity relationship: has_function CCO:F0002748 ! solute:hydrogen antiporter activity relationship: has_function CCO:F0002809 ! sodium:hydrogen antiporter activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017822 ! cftr-nhe2-1 physical interaction relationship: participates_in CCO:I0018717 ! cftr-nhe2 physical interaction [Term] id: CCO:B0020207 name: KCIP1_HUMAN def: "Kv channel-interacting protein 1" [UniProtKB:Q9NZI2] synonym: "A-type potassium channel modulatory protein 1" EXACT [UniProtKB:Q9NZI2] synonym: "KChIP1" EXACT [UniProtKB:Q9NZI2] synonym: "Potassium channel-interacting protein 1" EXACT [UniProtKB:Q9NZI2] synonym: "Vesicle APC-binding protein" EXACT [UniProtKB:Q9NZI2] xref: EMBL:AAF33682.1 xref: EMBL:AAH50375.1 xref: EMBL:AAN77491.1 xref: EMBL:AAV51968.1 xref: UniProtKB:Q5U822 xref: UniProtKB:Q9NZI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018386 ! KCNIP1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020218 name: CSEN_HUMAN def: "Calsenilin" [UniProtKB:Q9Y2W7] synonym: "A-type potassium channel modulatory protein 3" EXACT [UniProtKB:Q9Y2W7] synonym: "DRE-antagonist modulator" EXACT [UniProtKB:Q9Y2W7] synonym: "DREAM" EXACT [UniProtKB:Q9Y2W7] synonym: "KChIP3" EXACT [UniProtKB:Q9Y2W7] synonym: "Kv channel-interacting protein 3" EXACT [UniProtKB:Q9Y2W7] xref: EMBL:AAD20350.1 xref: EMBL:AAF33684.1 xref: EMBL:AAH12850.1 xref: EMBL:AAK53711.1 xref: EMBL:AAV38878.1 xref: EMBL:AAY14752.1 xref: EMBL:CAB56835.1 xref: EMBL:CAB56836.1 xref: UniProtKB:Q53TJ5 xref: UniProtKB:Q96T40 xref: UniProtKB:Q9UJ84 xref: UniProtKB:Q9UJ85 xref: UniProtKB:Q9Y2W7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017472 ! KCNIP3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015734 ! csen-prv1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064549 ! CSEN_HUMAN-Phosphoserine63 [Term] id: CCO:B0020223 name: KCIP2_HUMAN def: "Kv channel-interacting protein 2" [UniProtKB:Q9NS61] synonym: "A-type potassium channel modulatory protein 2" EXACT [UniProtKB:Q9NS61] synonym: "Cardiac voltage-gated potassium channel modulatory subunit" EXACT [UniProtKB:Q9NS61] synonym: "KChIP2" EXACT [UniProtKB:Q9NS61] synonym: "Potassium channel-interacting protein 2" EXACT [UniProtKB:Q9NS61] xref: EMBL:AAF33683.1 xref: EMBL:AAG02120.1 xref: EMBL:AAG02121.1 xref: EMBL:AAH34685.1 xref: EMBL:AAK07674.1 xref: EMBL:AAK21972.1 xref: EMBL:AAK53707.1 xref: EMBL:AAK53708.1 xref: EMBL:AAK53709.1 xref: EMBL:AAK53710.1 xref: EMBL:AAK70356.1 xref: EMBL:AAP57633.1 xref: EMBL:BAA96740.1 xref: EMBL:BAA96741.1 xref: EMBL:BAB55052.1 xref: EMBL:CAB66656.1 xref: EMBL:CAB77054.1 xref: UniProtKB:Q7Z6F1 xref: UniProtKB:Q96K86 xref: UniProtKB:Q96T41 xref: UniProtKB:Q96T42 xref: UniProtKB:Q96T43 xref: UniProtKB:Q96T44 xref: UniProtKB:Q9H0N4 xref: UniProtKB:Q9HD10 xref: UniProtKB:Q9HD11 xref: UniProtKB:Q9NS60 xref: UniProtKB:Q9NS61 xref: UniProtKB:Q9NY10 xref: UniProtKB:Q9NZI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018387 ! KCNIP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067284 ! KCIP2_HUMAN-Phosphothreonine103 relationship: transforms_into CCO:B0067285 ! KCIP2_HUMAN-Phosphotyrosine111 [Term] id: CCO:B0020253 name: SOX12_HUMAN def: "SOX-12 protein" [UniProtKB:O15370] synonym: "SOX-22 protein" EXACT [UniProtKB:O15370] xref: EMBL:AAB69627.1 xref: EMBL:AAH67361.1 xref: EMBL:CAB81632.1 xref: UniProtKB:O15370 xref: UniProtKB:Q5D038 xref: UniProtKB:Q9NUD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008200 ! SOX12_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0020254 name: SOX11_HUMAN def: "Transcription factor SOX-11" [UniProtKB:P35716] xref: EMBL:AAB08518.1 xref: EMBL:BAA88122.1 xref: EMBL:CAA51519.1 xref: UniProtKB:P35716 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008199 ! SOX11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035673 ! SOX11_HUMAN-Phosphoserine278 relationship: transforms_into CCO:B0070748 ! SOX11_HUMAN-Phosphoserine206 [Term] id: CCO:B0020256 name: SOX1_HUMAN def: "SOX-1 protein" [UniProtKB:O00570] xref: EMBL:CAA73847.1 xref: EMBL:CAH72340.1 xref: EMBL:EAX09158.1 xref: UniProtKB:O00570 xref: UniProtKB:Q5W0Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008204 ! SOX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020258 name: O95131_HUMAN def: "SOX-27 protein" [UniProtKB:O95131] xref: EMBL:AAC94972.1 xref: UniProtKB:O95131 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008494 ! SOX27_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020259 name: SOX18_HUMAN def: "Transcription factor SOX-18" [UniProtKB:P35713] xref: EMBL:AAG48577.1 xref: EMBL:AAH38590.1 xref: EMBL:AAH73971.1 xref: EMBL:AAI11391.1 xref: EMBL:BAA94874.1 xref: EMBL:CAA46615.1 xref: EMBL:CAB95835.1 xref: EMBL:CAC16611.1 xref: UniProtKB:P35713 xref: UniProtKB:Q0VGA9 xref: UniProtKB:Q9NPH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008203 ! SOX18_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0020263 name: SOX21_HUMAN def: "Transcription factor SOX-21" [UniProtKB:Q9Y651] synonym: "SOX-A" EXACT [UniProtKB:Q9Y651] xref: EMBL:AAC95381.1 xref: EMBL:CAA46617.1 xref: EMBL:CAA50466.1 xref: UniProtKB:P35715 xref: UniProtKB:Q15504 xref: UniProtKB:Q9Y651 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008205 ! SOX21_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0020265 name: Q5W0Q1_HUMAN xref: UniProtKB:Q5W0Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020266 name: SOX30_HUMAN def: "Transcription factor SOX-30" [UniProtKB:O94993] xref: EMBL:AAH33492.2 xref: EMBL:BAA37146.1 xref: EMBL:BAA37149.1 xref: UniProtKB:O94993 xref: UniProtKB:O94995 xref: UniProtKB:Q8IYX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008207 ! SOX30_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015053 ! bambi-sox30 physical interaction relationship: participates_in CCO:I0015159 ! sox30-traf2 physical interaction relationship: participates_in CCO:I0015776 ! nudt3-sox30 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020267 name: SOX14_HUMAN def: "Transcription factor SOX-14" [UniProtKB:O95416] xref: EMBL:AAC94971.1 xref: EMBL:AAC95380.1 xref: EMBL:AAF76294.1 xref: EMBL:AAI06730.1 xref: EMBL:AAI06731.1 xref: EMBL:CAB43111.1 xref: UniProtKB:O95416 xref: UniProtKB:Q3KPH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008201 ! SOX14_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020275 name: SOX3_HUMAN def: "Transcription factor SOX-3" [UniProtKB:P41225] xref: EMBL:AAF73059.1 xref: EMBL:AAH93863.1 xref: EMBL:AAH93865.1 xref: EMBL:CAA46616.1 xref: EMBL:CAA50465.1 xref: EMBL:CAB87584.1 xref: UniProtKB:P35714 xref: UniProtKB:P41225 xref: UniProtKB:Q5JWI3 xref: UniProtKB:Q9NP49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008208 ! SOX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020282 name: SRY_HUMAN def: "Sex-determining region Y protein" [UniProtKB:Q05066] synonym: "Testis-determining factor" EXACT [UniProtKB:Q05066] xref: EMBL:AAA16878.1 xref: EMBL:AAA60590.1 xref: EMBL:AAA60591.1 xref: EMBL:AAB25008.1 xref: EMBL:AAB25716.1 xref: EMBL:AAH74923.1 xref: EMBL:AAH74924.1 xref: EMBL:CAA37790.1 xref: EMBL:CAA65281.1 xref: UniProtKB:Q05066 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008226 ! SRY_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0008962 ! smad3-sry-3 physical interaction relationship: participates_in CCO:I0008968 ! smad3-sry physical interaction relationship: participates_in CCO:I0008969 ! smad3-sry-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035694 ! SRY_HUMAN-N6-acetyllysine136 [Term] id: CCO:B0020283 name: SOX15_HUMAN def: "SOX-15 protein" [UniProtKB:O60248] synonym: "SOX-12 protein" EXACT [UniProtKB:O60248] synonym: "SOX-20 protein" EXACT [UniProtKB:O60248] xref: EMBL:AAH00985.1 xref: EMBL:AAH72003.1 xref: EMBL:BAA25663.1 xref: EMBL:BAA78784.1 xref: EMBL:CAA06920.1 xref: EMBL:CAA51520.1 xref: UniProtKB:O60248 xref: UniProtKB:P35717 xref: UniProtKB:Q9Y6W7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008202 ! SOX15_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0020286 name: O95130_HUMAN def: "SOX-26 protein" [UniProtKB:O95130] xref: EMBL:AAC94970.1 xref: UniProtKB:O95130 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008493 ! SOX26_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020290 name: Q7Z5C6_HUMAN def: "SRY" [UniProtKB:Q7Z5C6] xref: EMBL:AAP88268.1 xref: UniProtKB:Q7Z5C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008226 ! SRY_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020291 name: O95132_HUMAN def: "SOX-28 protein" [UniProtKB:O95132] xref: EMBL:AAC94973.1 xref: UniProtKB:O95132 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008495 ! SOX28_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020292 name: SOX4_HUMAN def: "Transcription factor SOX-4" [UniProtKB:Q06945] xref: EMBL:AAH72668.1 xref: EMBL:CAA46612.1 xref: EMBL:CAA50018.1 xref: EMBL:CAC03595.1 xref: UniProtKB:Q06945 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008209 ! SOX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035674 ! SOX4_HUMAN-Phosphoserine276 [Term] id: CCO:B0020295 name: SOX2_HUMAN def: "Transcription factor SOX-2" [UniProtKB:P48431] xref: EMBL:AAA35997.1 xref: EMBL:AAH13923.1 xref: EMBL:CAA83435.1 xref: UniProtKB:P48431 xref: UniProtKB:Q14537 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008206 ! SOX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0020296 name: Q52MY2_HUMAN def: "Mutant SRY protein" [UniProtKB:Q52MY2] xref: EMBL:AAY15121.1 xref: UniProtKB:Q52MY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008226 ! SRY_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020321 name: MIER1_HUMAN def: "Mesoderm induction early response protein 1" [UniProtKB:Q8N108] synonym: "Early response 1" EXACT [UniProtKB:Q8N108] synonym: "Er1" EXACT [UniProtKB:Q8N108] synonym: "hmi-er1" EXACT [UniProtKB:Q8N108] synonym: "Mi-er1" EXACT [UniProtKB:Q8N108] xref: EMBL:AAH17423.1 xref: EMBL:AAM76040.1 xref: EMBL:AAM76041.1 xref: EMBL:AAM76042.1 xref: EMBL:AAM97499.1 xref: EMBL:AAM97500.1 xref: EMBL:AAM97501.1 xref: EMBL:AAM97502.1 xref: EMBL:AAM97503.1 xref: EMBL:AAM97504.1 xref: EMBL:AAM97505.1 xref: EMBL:AAM97506.1 xref: EMBL:AAM97507.1 xref: EMBL:BAB13436.1 xref: EMBL:BAC11339.1 xref: EMBL:CAD89921.1 xref: EMBL:CAH10526.1 xref: EMBL:CAI18875.1 xref: EMBL:CAI18878.1 xref: EMBL:CAI18879.1 xref: EMBL:CAI23429.1 xref: EMBL:CAI23431.1 xref: EMBL:CAI23432.1 xref: UniProtKB:Q5T104 xref: UniProtKB:Q6AHY8 xref: UniProtKB:Q86TB4 xref: UniProtKB:Q8N108 xref: UniProtKB:Q8N156 xref: UniProtKB:Q8N161 xref: UniProtKB:Q8NC37 xref: UniProtKB:Q8NES4 xref: UniProtKB:Q8NES5 xref: UniProtKB:Q8NES6 xref: UniProtKB:Q8WWG2 xref: UniProtKB:Q9HCG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018620 ! MIER1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0068174 ! MIER1_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0068175 ! MIER1_HUMAN-Phosphotyrosine179 relationship: transforms_into CCO:B0068176 ! MIER1_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0068177 ! MIER1_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0068178 ! MIER1_HUMAN-Phosphoserine401 relationship: transforms_into CCO:B0068179 ! MIER1_HUMAN-Phosphothreonine405 relationship: transforms_into CCO:B0068180 ! MIER1_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0068181 ! MIER1_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0068182 ! MIER1_HUMAN-Phosphoserine512 [Term] id: CCO:B0020366 name: ACVL1_HUMAN def: "Serine/threonine-protein kinase receptor R3 precursor" [UniProtKB:P37023] synonym: "Activin receptor-like kinase 1" EXACT [UniProtKB:P37023] synonym: "ALK-1" EXACT [UniProtKB:P37023] synonym: "EC 2.7.11.30" EXACT [UniProtKB:P37023] synonym: "SKR3" EXACT [UniProtKB:P37023] synonym: "TGF-B superfamily receptor type I" EXACT [UniProtKB:P37023] synonym: "TSR-I" EXACT [UniProtKB:P37023] xref: EMBL:AAA16160.1 xref: EMBL:AAB61900.1 xref: EMBL:AAH42637.1 xref: EMBL:CAA80255.1 xref: EMBL:EAW58213.1 xref: UniProtKB:A6NGA8 xref: UniProtKB:P37023 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011223 ! ACVRL1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001355 ! transforming growth factor beta receptor activity, type I relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003122 ! activin receptor activity, type I relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007319 ! activin binding relationship: has_function CCO:F0007780 ! transforming growth factor beta binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001003 ! negative regulation of endothelial cell migration relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001274 ! positive regulation of BMP signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0003156 ! negative regulation of focal adhesion formation [Term] id: CCO:B0020367 name: Q6IR47_HUMAN def: "TGFBR1 protein" [UniProtKB:Q6IR47] xref: EMBL:AAH71181.1 xref: UniProtKB:Q6IR47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011707 ! TGFBR1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway [Term] id: CCO:B0020368 name: ACV1C_HUMAN def: "Activin receptor type-1C precursor" [UniProtKB:Q8NER5] synonym: "Activin receptor-like kinase 7" EXACT [UniProtKB:Q8NER5] synonym: "ACTR-IC" EXACT [UniProtKB:Q8NER5] synonym: "ALK-7" EXACT [UniProtKB:Q8NER5] synonym: "EC 2.7.11.30" EXACT [UniProtKB:Q8NER5] xref: EMBL:AAH22530.1 xref: EMBL:AAM93495.1 xref: EMBL:AAP21993.1 xref: EMBL:AAP21994.1 xref: EMBL:AAP21995.1 xref: EMBL:AAX88951.1 xref: UniProtKB:Q4ZFZ8 xref: UniProtKB:Q86UL1 xref: UniProtKB:Q86UL2 xref: UniProtKB:Q8NER5 xref: UniProtKB:Q8TBG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011222 ! ACVR1C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003122 ! activin receptor activity, type I relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001980 ! activin receptor complex relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0020370 name: TGFR1_HUMAN def: "TGF-beta receptor type-1 precursor" [UniProtKB:P36897] synonym: "Activin receptor-like kinase 5" EXACT [UniProtKB:P36897] synonym: "ALK-5" EXACT [UniProtKB:P36897] synonym: "EC 2.7.11.30" EXACT [UniProtKB:P36897] synonym: "Serine/threonine-protein kinase receptor R4" EXACT [UniProtKB:P36897] synonym: "SKR4" EXACT [UniProtKB:P36897] synonym: "TbetaR-I" EXACT [UniProtKB:P36897] synonym: "TGF-beta receptor type I" EXACT [UniProtKB:P36897] synonym: "TGF-beta type I receptor" EXACT [UniProtKB:P36897] synonym: "TGFR-1" EXACT [UniProtKB:P36897] synonym: "Transforming growth factor-beta receptor type I" EXACT [UniProtKB:P36897] xref: EMBL:AAA16073.1 xref: EMBL:AAC08998.1 xref: EMBL:AAD02042.1 xref: EMBL:AAR32097.1 xref: UniProtKB:P36897 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011707 ! TGFBR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015858 ! fkbp1a-tgfbr1-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0000721 ! transforming growth factor beta receptor complex assembly relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0039673 ! TGFR1_HUMAN-Phosphothreonine185 relationship: transforms_into CCO:B0039674 ! TGFR1_HUMAN-Phosphothreonine186 relationship: transforms_into CCO:B0039675 ! TGFR1_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0039676 ! TGFR1_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0039677 ! TGFR1_HUMAN-Phosphoserine191 [Term] id: CCO:B0020371 name: BMR1B_HUMAN def: "Bone morphogenetic protein receptor type-1B precursor" [UniProtKB:O00238] synonym: "CDw293 antigen" EXACT [UniProtKB:O00238] synonym: "EC 2.7.11.30" EXACT [UniProtKB:O00238] xref: EMBL:AAC28131.1 xref: EMBL:AAH47773.1 xref: EMBL:AAH69796.1 xref: EMBL:AAH69803.1 xref: EMBL:BAA19765.1 xref: UniProtKB:O00238 xref: UniProtKB:P78366 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011262 ! BMPR1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001355 ! transforming growth factor beta receptor activity, type I relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001751 ! receptor complex relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation [Term] id: CCO:B0020414 name: KC1G3_HUMAN def: "Casein kinase I isoform gamma-3" [UniProtKB:Q9Y6M4] synonym: "CKI-gamma 3" EXACT [UniProtKB:Q9Y6M4] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y6M4] xref: EMBL:AAD26525.1 xref: EMBL:AAD26526.1 xref: EMBL:AAH47567.1 xref: UniProtKB:Q86WZ7 xref: UniProtKB:Q9Y6M3 xref: UniProtKB:Q9Y6M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018382 ! CSNK1G3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0020417 name: KC1G1_HUMAN def: "Casein kinase I isoform gamma-1" [UniProtKB:Q9HCP0] synonym: "CKI-gamma 1" EXACT [UniProtKB:Q9HCP0] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9HCP0] xref: EMBL:AAH17236.2 xref: EMBL:BAB17838.1 xref: EMBL:BAB17839.1 xref: UniProtKB:Q96AE9 xref: UniProtKB:Q9HCP0 xref: UniProtKB:Q9HCP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018380 ! CSNK1G1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0020420 name: KC1G2_HUMAN def: "Casein kinase I isoform gamma-2" [UniProtKB:P78368] synonym: "CKI-gamma 2" EXACT [UniProtKB:P78368] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P78368] xref: EMBL:AAB88627.1 xref: EMBL:AAC00212.1 xref: EMBL:AAC26983.1 xref: EMBL:AAH18693.1 xref: EMBL:AAH18699.1 xref: EMBL:AAH20972.1 xref: EMBL:AAP88924.1 xref: UniProtKB:O00704 xref: UniProtKB:P78368 xref: UniProtKB:Q8WUB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018381 ! CSNK1G2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001051 ! casein kinase I activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015422 ! col4a3bp-csnk1g2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0020438 name: A6NNS1_HUMAN def: "Putative uncharacterized protein PES1" [UniProtKB:A6NNS1] xref: UniProtKB:A6NNS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005298 ! PES1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0020445 name: Q5XG96_HUMAN def: "PMS1 protein" [UniProtKB:Q5XG96] xref: EMBL:AAH84548.1 xref: UniProtKB:Q5XG96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005345 ! PMS1_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0020446 name: Q5FBZ4_HUMAN def: "PMS1 nirs variant 6" [UniProtKB:Q5FBZ4] xref: EMBL:BAD89403.1 xref: UniProtKB:Q5FBZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005345 ! PMS1_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0020448 name: Q96HL0_HUMAN def: "PMS1 postmeiotic segregation increased 1 (S. cerevisiae)" [UniProtKB:Q96HL0] synonym: "PMS1 protein" EXACT [UniProtKB:Q96HL0] xref: EMBL:AAH08410.1 xref: EMBL:AAP35593.1 xref: UniProtKB:Q96HL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0020453 name: Q3BDU4_HUMAN def: "Rhabdomyosarcoma antigen MU-RMS-40.10B" [UniProtKB:Q3BDU4] xref: EMBL:ABB04019.1 xref: UniProtKB:Q3BDU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005345 ! PMS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0020481 name: RET1G_HUMAN def: "Retinoic acid early transcript 1G protein precursor" [UniProtKB:Q6H3X3] xref: EMBL:AAO22238.1 xref: EMBL:AAO22239.1 xref: UniProtKB:Q6H3X2 xref: UniProtKB:Q6H3X3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008076 ! RAET1G_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001669 ! MHC class I protein complex relationship: participates_in CCO:I0015902 ! raet1g-klrk1-1 physical interaction [Term] id: CCO:B0020491 name: N2DL3_HUMAN def: "NKG2D ligand 3 precursor" [UniProtKB:Q9BZM4] synonym: "ALCAN-gamma" EXACT [UniProtKB:Q9BZM4] synonym: "N2DL-3" EXACT [UniProtKB:Q9BZM4] synonym: "NKG2DL3" EXACT [UniProtKB:Q9BZM4] synonym: "Retinoic acid early transcript 1N" EXACT [UniProtKB:Q9BZM4] xref: EMBL:AAK13049.1 xref: EMBL:AAK13083.1 xref: EMBL:AAN40839.1 xref: EMBL:BAB61050.1 xref: UniProtKB:Q8IZX5 xref: UniProtKB:Q8TE75 xref: UniProtKB:Q9BZM4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007862 ! ULBP3_human relationship: has_function CCO:F0004977 ! MHC class I receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001669 ! MHC class I protein complex relationship: participates_in CCO:I0018706 ! klrk1-ulbp3-1 direct interaction [Term] id: CCO:B0020493 name: RD23B_HUMAN def: "UV excision repair protein RAD23 homolog B" [UniProtKB:P54727] synonym: "hHR23B" EXACT [UniProtKB:P54727] synonym: "p58" EXACT [UniProtKB:P54727] synonym: "XP-C repair-complementing complex 58 kDa protein" EXACT [UniProtKB:P54727] xref: EMBL:AAH20973.1 xref: EMBL:AAN47194.1 xref: EMBL:BAA04652.1 xref: EMBL:CAD13275.1 xref: UniProtKB:P54727 xref: UniProtKB:Q8WUB0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008073 ! RAD23B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017615 ! atxn3-rad23b physical interaction relationship: transforms_into CCO:B0035538 ! RD23B_HUMAN-Phosphothreonine155 relationship: transforms_into CCO:B0035539 ! RD23B_HUMAN-Phosphoserine160 [Term] id: CCO:B0020505 name: PGFRA_HUMAN def: "Alpha-type platelet-derived growth factor receptor precursor" [UniProtKB:P16234] synonym: "CD140 antigen-like family member A" EXACT [UniProtKB:P16234] synonym: "CD140a antigen" EXACT [UniProtKB:P16234] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P16234] synonym: "PDGF-R-alpha" EXACT [UniProtKB:P16234] xref: EMBL:AAA60048.1 xref: EMBL:AAA96715.1 xref: EMBL:AAH15186.1 xref: EMBL:AAP69563.1 xref: EMBL:BAA08742.1 xref: UniProtKB:P16234 xref: UniProtKB:Q96KZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007970 ! PDGFRA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: transforms_into CCO:B0035366 ! PGFRA_HUMAN-Phosphotyrosine849 relationship: transforms_into CCO:B0039581 ! PGFRA_HUMAN-Phosphotyrosine720 relationship: transforms_into CCO:B0069241 ! PGFRA_HUMAN-Phosphotyrosine762 relationship: transforms_into CCO:B0069242 ! PGFRA_HUMAN-Phosphotyrosine768 relationship: transforms_into CCO:B0069243 ! PGFRA_HUMAN-Phosphotyrosine1018 [Term] id: CCO:B0020508 name: PGFRB_HUMAN def: "Beta-type platelet-derived growth factor receptor precursor" [UniProtKB:P09619] synonym: "CD140 antigen-like family member B" EXACT [UniProtKB:P09619] synonym: "CD140b antigen" EXACT [UniProtKB:P09619] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P09619] synonym: "PDGF-R-beta" EXACT [UniProtKB:P09619] xref: EMBL:AAA36427.1 xref: EMBL:AAA60049.1 xref: EMBL:AAC51675.1 xref: EMBL:AAH32224.1 xref: UniProtKB:P09619 xref: UniProtKB:Q8N5L4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007971 ! PDGFRB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015710 ! krtap4_12-pdgfrb physical interaction relationship: participates_in CCO:I0019390 ! pdgfr-pik3c2b-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation relationship: transforms_into CCO:B0035367 ! PGFRB_HUMAN-Phosphotyrosine751 relationship: transforms_into CCO:B0035368 ! PGFRB_HUMAN-Phosphotyrosine857 [Term] id: CCO:B0020529 name: IMA7_HUMAN def: "Importin subunit alpha-7" [UniProtKB:O60684] synonym: "Karyopherin subunit alpha-6" EXACT [UniProtKB:O60684] xref: EMBL:AAC15233.1 xref: EMBL:AAH20520.1 xref: EMBL:AAP88845.1 xref: EMBL:CAH71948.1 xref: EMBL:CAI22056.1 xref: EMBL:EAX07567.1 xref: UniProtKB:O60684 xref: UniProtKB:Q5VVU3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011489 ! KPNA6_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017247 ! relb-kpna6 physical interaction relationship: participates_in CCO:I0017625 ! taf9-kpna6-1 physical interaction relationship: participates_in CCO:I0019150 ! anp32a-kpna6 physical interaction relationship: transforms_into CCO:B0039473 ! IMA7_HUMAN-Phosphoserine6 [Term] id: CCO:B0020532 name: IMA1_HUMAN def: "Importin subunit alpha-1" [UniProtKB:P52294] synonym: "Karyopherin subunit alpha-1" EXACT [UniProtKB:P52294] synonym: "NPI-1" EXACT [UniProtKB:P52294] synonym: "Nucleoprotein interactor 1" EXACT [UniProtKB:P52294] synonym: "RAG cohort protein 2" EXACT [UniProtKB:P52294] synonym: "SRP1-beta" EXACT [UniProtKB:P52294] xref: EMBL:AAC60648.1 xref: EMBL:AAH02374.1 xref: EMBL:AAH03009.1 xref: EMBL:AAP35605.1 xref: UniProtKB:P52294 xref: UniProtKB:Q9BQ56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011488 ! KPNA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016852 ! relb-kpna1 physical interaction relationship: participates_in CCO:I0017624 ! taf9-kpna1 physical interaction relationship: participates_in CCO:I0019148 ! anp32a-kpna1 physical interaction relationship: participates_in CCO:P0000398 ! regulation of DNA recombination relationship: transforms_into CCO:B0039472 ! IMA1_HUMAN-Phosphothreonine3 [Term] id: CCO:B0020552 name: RING2_HUMAN def: "E3 ubiquitin-protein ligase RING2" [UniProtKB:Q99496] synonym: "DinG protein" EXACT [UniProtKB:Q99496] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q99496] synonym: "HIP2-interacting protein 3" EXACT [UniProtKB:Q99496] synonym: "Huntingtin-interacting protein 2-interacting protein 3" EXACT [UniProtKB:Q99496] synonym: "RING finger protein 1B" EXACT [UniProtKB:Q99496] synonym: "RING finger protein 2" EXACT [UniProtKB:Q99496] synonym: "RING finger protein BAP-1" EXACT [UniProtKB:Q99496] synonym: "RING1b" EXACT [UniProtKB:Q99496] xref: EMBL:AAD29717.1 xref: EMBL:AAH12583.1 xref: EMBL:CAA71596.1 xref: EMBL:CAC00611.1 xref: EMBL:CAI17849.1 xref: EMBL:CAI17850.1 xref: UniProtKB:Q5TEN1 xref: UniProtKB:Q5TEN2 xref: UniProtKB:Q99496 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008104 ! RNF2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0016009 ! abcb1-rnf2 physical interaction relationship: participates_in CCO:I0017492 ! abcb1-rnf2-1 physical interaction relationship: participates_in CCO:I0020439 ! rnf2-cbx4 physical interaction relationship: participates_in CCO:I0020654 ! rnf2-sumo2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035580 ! RING2_HUMAN-Phosphoserine168 [Term] id: CCO:B0020553 name: RING1_HUMAN def: "E3 ubiquitin-protein ligase RING1" [UniProtKB:Q06587] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q06587] synonym: "Polycomb complex protein RING1" EXACT [UniProtKB:Q06587] synonym: "RING finger protein 1" EXACT [UniProtKB:Q06587] xref: EMBL:AAH02922.2 xref: EMBL:AAH51866.1 xref: EMBL:AAP36016.1 xref: EMBL:CAA20235.1 xref: EMBL:CAA78389.1 xref: EMBL:CAI17650.1 xref: EMBL:CAI18069.1 xref: EMBL:CAI41841.1 xref: EMBL:CAI95620.1 xref: UniProtKB:Q06587 xref: UniProtKB:Q5JP96 xref: UniProtKB:Q5SQW2 xref: UniProtKB:Q86V19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008103 ! RING1_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001238 ! retinoid-X receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004420 ! thyroid hormone receptor coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0005774 ! retinoic acid receptor binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000182 ! sex chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000817 ! nuclear body relationship: located_in CCO:C0000820 ! nuclear speck relationship: located_in CCO:C0001285 ! PcG protein complex relationship: participates_in CCO:I0015833 ! ring1-rybp physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052689 ! RING1_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0070055 ! RING1_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0070056 ! RING1_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0070057 ! RING1_HUMAN-Phosphoserine190 [Term] id: CCO:B0020556 name: PLD1_HUMAN def: "Phospholipase D1" [UniProtKB:Q13393] synonym: "Choline phosphatase 1" EXACT [UniProtKB:Q13393] synonym: "EC 3.1.4.4" EXACT [UniProtKB:Q13393] synonym: "hPLD1" EXACT [UniProtKB:Q13393] synonym: "Phosphatidylcholine-hydrolyzing phospholipase D1" EXACT [UniProtKB:Q13393] synonym: "PLD 1" EXACT [UniProtKB:Q13393] xref: EMBL:AAB49031.1 xref: EMBL:AAH68976.1 xref: EMBL:CAB76564.1 xref: UniProtKB:Q13393 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007983 ! PLD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 [Term] id: CCO:B0020561 name: PLD2_HUMAN def: "Phospholipase D2" [UniProtKB:O14939] synonym: "Choline phosphatase 2" EXACT [UniProtKB:O14939] synonym: "EC 3.1.4.4" EXACT [UniProtKB:O14939] synonym: "hPLD2" EXACT [UniProtKB:O14939] synonym: "Phosphatidylcholine-hydrolyzing phospholipase D2" EXACT [UniProtKB:O14939] synonym: "PLD 2" EXACT [UniProtKB:O14939] synonym: "PLD1C" EXACT [UniProtKB:O14939] xref: EMBL:AAB96655.1 xref: EMBL:AAB96656.1 xref: EMBL:AAC24498.1 xref: EMBL:AAD04197.1 xref: EMBL:AAH15033.1 xref: UniProtKB:O14939 xref: UniProtKB:O43540 xref: UniProtKB:O43579 xref: UniProtKB:O43580 xref: UniProtKB:Q96BY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007984 ! PLD2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001004 ! phospholipase D activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001290 ! brush border membrane relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000520 ! G-protein coupled receptor internalization relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0020567 name: Q9NXX9_HUMAN def: "FLJ00006 protein" [UniProtKB:Q9NXX9] xref: EMBL:BAA92231.1 xref: UniProtKB:Q9NXX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008976 ! FLJ00006_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0020591 name: RHOA_HUMAN def: "Transforming protein RhoA precursor" [UniProtKB:P61586] synonym: "H12" EXACT [UniProtKB:P61586] xref: EMBL:AAA50612.1 xref: EMBL:AAA67539.1 xref: EMBL:AAC33178.1 xref: EMBL:AAH01360.1 xref: EMBL:AAH05976.1 xref: EMBL:AAM21117.1 xref: EMBL:AAV38673.1 xref: EMBL:CAA28690.1 xref: EMBL:CAE46190.1 xref: UniProtKB:P06749 xref: UniProtKB:P61586 xref: UniProtKB:Q5U024 xref: UniProtKB:Q9UEJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011655 ! RHOA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015844 ! arhgap1-rhoa physical interaction relationship: participates_in CCO:I0017267 ! arhgap1-rhoa-1 direct interaction relationship: participates_in CCO:I0017952 ! arhgdia-rhoa-1 direct interaction relationship: participates_in CCO:I0018704 ! arhgef12-rhoa-1 direct interaction relationship: participates_in CCO:I0018709 ! arhgef11-rhoa-1 direct interaction relationship: participates_in CCO:I0018742 ! pkn1-rhoa-1 direct interaction relationship: participates_in CCO:I0018826 ! rhoa-arhgef5-3 physical interaction relationship: participates_in CCO:I0019324 ! rhoa-rock1-1 direct interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0039620 ! RHOA_HUMAN-ADP-ribosylasparagine41 relationship: transforms_into CCO:B0039621 ! RHOA_HUMAN-Cysteine methyl ester190 [Term] id: CCO:B0020594 name: RHOC_HUMAN def: "Rho-related GTP-binding protein RhoC precursor" [UniProtKB:P08134] synonym: "H9" EXACT [UniProtKB:P08134] xref: EMBL:AAC33179.1 xref: EMBL:AAH07245.1 xref: EMBL:AAH09177.1 xref: EMBL:AAH52808.1 xref: EMBL:AAM21119.1 xref: EMBL:AAV38255.1 xref: EMBL:CAA29969.1 xref: EMBL:CAG29356.1 xref: EMBL:CAI14058.1 xref: UniProtKB:P08134 xref: UniProtKB:Q6ICN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011656 ! RHOC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015353 ! arhgap1-rhoc physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0039622 ! RHOC_HUMAN-Phosphothreonine19 relationship: transforms_into CCO:B0039623 ! RHOC_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0039624 ! RHOC_HUMAN-ADP-ribosylasparagine41 relationship: transforms_into CCO:B0039625 ! RHOC_HUMAN-Cysteine methyl ester190 [Term] id: CCO:B0020597 name: Q5JR08_HUMAN def: "Ras homolog gene family, member C" [UniProtKB:Q5JR08] xref: EMBL:CAI14059.1 xref: UniProtKB:Q5JR08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011656 ! RHOC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0020601 name: GRIA2_HUMAN def: "Glutamate receptor 2 precursor" [UniProtKB:P42262] synonym: "AMPA-selective glutamate receptor 2" EXACT [UniProtKB:P42262] synonym: "GluR-2" EXACT [UniProtKB:P42262] synonym: "GluR-B" EXACT [UniProtKB:P42262] synonym: "GluR-K2" EXACT [UniProtKB:P42262] synonym: "Glutamate receptor ionotropic, AMPA 2" EXACT [UniProtKB:P42262] xref: EMBL:AAA58631.1 xref: EMBL:AAH10574.1 xref: UniProtKB:P42262 xref: UniProtKB:Q96FP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018061 ! GRIA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066602 ! GRIA2_HUMAN-Phosphoserine683 relationship: transforms_into CCO:B0066603 ! GRIA2_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0066604 ! GRIA2_HUMAN-Phosphotyrosine869 relationship: transforms_into CCO:B0066605 ! GRIA2_HUMAN-Phosphotyrosine876 relationship: transforms_into CCO:B0066606 ! GRIA2_HUMAN-Phosphoserine880 [Term] id: CCO:B0020605 name: GRIK3_HUMAN def: "Glutamate receptor, ionotropic kainate 3 precursor" [UniProtKB:Q13003] synonym: "EAA5" EXACT [UniProtKB:Q13003] synonym: "Excitatory amino acid receptor 5" EXACT [UniProtKB:Q13003] synonym: "GluR-7" EXACT [UniProtKB:Q13003] synonym: "GluR7" EXACT [UniProtKB:Q13003] synonym: "Glutamate receptor 7" EXACT [UniProtKB:Q13003] xref: EMBL:AAB30157.1 xref: EMBL:AAB60407.1 xref: EMBL:AAC50421.1 xref: EMBL:CAI19119.1 xref: EMBL:EAX07351.1 xref: UniProtKB:B1AMS6 xref: UniProtKB:Q13003 xref: UniProtKB:Q13004 xref: UniProtKB:Q16136 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018067 ! GRIK3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001695 ! glutamate receptor activity relationship: has_function CCO:F0002734 ! kainate selective glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000750 ! glutamate signaling pathway relationship: transforms_into CCO:B0066611 ! GRIK3_HUMAN-Phosphotyrosine544 [Term] id: CCO:B0020611 name: GRIK2_HUMAN def: "Glutamate receptor, ionotropic kainate 2 precursor" [UniProtKB:Q13002] synonym: "EAA4" EXACT [UniProtKB:Q13002] synonym: "Excitatory amino acid receptor 4" EXACT [UniProtKB:Q13002] synonym: "GluR-6" EXACT [UniProtKB:Q13002] synonym: "GluR6" EXACT [UniProtKB:Q13002] synonym: "Glutamate receptor 6" EXACT [UniProtKB:Q13002] xref: EMBL:AAC50420.1 xref: EMBL:CAC67485.1 xref: EMBL:CAC67486.1 xref: EMBL:CAC67487.1 xref: EMBL:CAC81020.1 xref: UniProtKB:Q13002 xref: UniProtKB:Q8WWS1 xref: UniProtKB:Q96KS6 xref: UniProtKB:Q96KS7 xref: UniProtKB:Q96KS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018066 ! GRIK2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0002734 ! kainate selective glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000750 ! glutamate signaling pathway relationship: participates_in CCO:P0001465 ! induction of programmed cell death in response to chemical stimulus relationship: participates_in CCO:P0002789 ! regulation of short-term neuronal synaptic plasticity relationship: participates_in CCO:P0002958 ! regulation of synaptic transmission relationship: participates_in CCO:P0002960 ! positive regulation of synaptic transmission [Term] id: CCO:B0020614 name: GRIK1_HUMAN def: "Glutamate receptor, ionotropic kainate 1 precursor" [UniProtKB:P39086] synonym: "EAA3" EXACT [UniProtKB:P39086] synonym: "Excitatory amino acid receptor 3" EXACT [UniProtKB:P39086] synonym: "GluR-5" EXACT [UniProtKB:P39086] synonym: "GluR5" EXACT [UniProtKB:P39086] synonym: "Glutamate receptor 5" EXACT [UniProtKB:P39086] xref: EMBL:AAA52568.1 xref: EMBL:AAA95961.1 xref: EMBL:CAC80546.1 xref: UniProtKB:P39086 xref: UniProtKB:Q13001 xref: UniProtKB:Q86SU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018065 ! GRIK1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001524 ! cation channel activity relationship: has_function CCO:F0002734 ! kainate selective glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000750 ! glutamate signaling pathway relationship: participates_in CCO:P0003169 ! regulation of synaptic transmission, glutamatergic relationship: transforms_into CCO:B0066609 ! GRIK1_HUMAN-Phosphoserine725 relationship: transforms_into CCO:B0066610 ! GRIK1_HUMAN-Phosphothreonine761 [Term] id: CCO:B0020617 name: GRIK4_HUMAN def: "Glutamate receptor, ionotropic kainate 4 precursor" [UniProtKB:Q16099] synonym: "EAA1" EXACT [UniProtKB:Q16099] synonym: "Excitatory amino acid receptor 1" EXACT [UniProtKB:Q16099] synonym: "Glutamate receptor KA-1" EXACT [UniProtKB:Q16099] synonym: "KA1" EXACT [UniProtKB:Q16099] xref: EMBL:AAB29311.1 xref: EMBL:BAF85415.1 xref: EMBL:EAW67512.1 xref: UniProtKB:A8K9L1 xref: UniProtKB:Q16099 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018068 ! GRIK4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0002734 ! kainate selective glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000750 ! glutamate signaling pathway [Term] id: CCO:B0020622 name: GRIA3_HUMAN def: "Glutamate receptor 3 precursor" [UniProtKB:P42263] synonym: "AMPA-selective glutamate receptor 3" EXACT [UniProtKB:P42263] synonym: "GluR-3" EXACT [UniProtKB:P42263] synonym: "GluR-C" EXACT [UniProtKB:P42263] synonym: "GluR-K3" EXACT [UniProtKB:P42263] synonym: "Glutamate receptor ionotropic, AMPA 3" EXACT [UniProtKB:P42263] xref: EMBL:AAA67922.1 xref: EMBL:AAA67923.1 xref: EMBL:AAF97857.1 xref: EMBL:AAF97858.1 xref: EMBL:AAF97859.1 xref: EMBL:CAA57567.1 xref: EMBL:CAI95164.1 xref: EMBL:CAI95165.1 xref: EMBL:CAI95643.1 xref: EMBL:CAI95644.1 xref: EMBL:CAI95664.1 xref: EMBL:CAI95665.1 xref: EMBL:CAI95683.1 xref: EMBL:CAI95684.1 xref: EMBL:CAI95709.1 xref: EMBL:CAI95710.1 xref: UniProtKB:P42263 xref: UniProtKB:Q4VXD5 xref: UniProtKB:Q4VXD6 xref: UniProtKB:Q9HDA0 xref: UniProtKB:Q9HDA1 xref: UniProtKB:Q9HDA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018062 ! GRIA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000750 ! glutamate signaling pathway relationship: transforms_into CCO:B0066607 ! GRIA3_HUMAN-Phosphotyrosine877 relationship: transforms_into CCO:B0066608 ! GRIA3_HUMAN-Phosphotyrosine887 [Term] id: CCO:B0020623 name: GRIA4_HUMAN def: "Glutamate receptor 4 precursor" [UniProtKB:P48058] synonym: "AMPA-selective glutamate receptor 4" EXACT [UniProtKB:P48058] synonym: "GluR-4" EXACT [UniProtKB:P48058] synonym: "GluR-D" EXACT [UniProtKB:P48058] synonym: "GluR4" EXACT [UniProtKB:P48058] synonym: "Glutamate receptor ionotropic, AMPA 4" EXACT [UniProtKB:P48058] xref: EMBL:AAA95962.1 xref: UniProtKB:P48058 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018063 ! GRIA4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000750 ! glutamate signaling pathway [Term] id: CCO:B0020627 name: GRIA1_HUMAN def: "Glutamate receptor 1 precursor" [UniProtKB:P42261] synonym: "AMPA-selective glutamate receptor 1" EXACT [UniProtKB:P42261] synonym: "GluR-1" EXACT [UniProtKB:P42261] synonym: "GluR-A" EXACT [UniProtKB:P42261] synonym: "GluR-K1" EXACT [UniProtKB:P42261] synonym: "Glutamate receptor ionotropic, AMPA 1" EXACT [UniProtKB:P42261] xref: EMBL:AAA58395.1 xref: EMBL:AAA58613.1 xref: EMBL:AAI11735.1 xref: EMBL:CAA41491.1 xref: UniProtKB:P42261 xref: UniProtKB:Q2NKM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018060 ! GRIA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066598 ! GRIA1_HUMAN-Phosphoserine645 relationship: transforms_into CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: transforms_into CCO:B0066600 ! GRIA1_HUMAN-Phosphoserine849 relationship: transforms_into CCO:B0066601 ! GRIA1_HUMAN-Phosphoserine863 [Term] id: CCO:B0020639 name: XRCC1_HUMAN def: "DNA repair protein XRCC1" [UniProtKB:P18887] synonym: "X-ray repair cross-complementing protein 1" EXACT [UniProtKB:P18887] xref: EMBL:AAA63270.1 xref: EMBL:AAG09061.1 xref: EMBL:AAM34791.1 xref: UniProtKB:P18887 xref: UniProtKB:Q9HCB1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008357 ! XRCC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018914 ! aptx-xrcc1 physical interaction relationship: participates_in CCO:I0018917 ! aptx-xrcc1-1 physical interaction relationship: transforms_into CCO:B0035836 ! XRCC1_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0035837 ! XRCC1_HUMAN-Phosphoserine371 relationship: transforms_into CCO:B0035838 ! XRCC1_HUMAN-Phosphoserine408 relationship: transforms_into CCO:B0035839 ! XRCC1_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0035840 ! XRCC1_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0035841 ! XRCC1_HUMAN-Phosphoserine416 relationship: transforms_into CCO:B0035842 ! XRCC1_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0035843 ! XRCC1_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0035844 ! XRCC1_HUMAN-Phosphoserine447 relationship: transforms_into CCO:B0035845 ! XRCC1_HUMAN-Phosphothreonine453 [Term] id: CCO:B0020731 name: TAGAP_HUMAN def: "T-cell activation Rho GTPase-activating protein" [UniProtKB:Q8N103] synonym: "T-cell activation GTPase-activating protein" EXACT [UniProtKB:Q8N103] xref: EMBL:AAH15859.1 xref: EMBL:AAI11732.1 xref: EMBL:AAL16675.1 xref: EMBL:AAM43830.1 xref: EMBL:AAM43831.1 xref: EMBL:BAC04947.1 xref: EMBL:CAI19231.1 xref: EMBL:CAI19232.1 xref: EMBL:CAI19233.1 xref: UniProtKB:Q2NKM8 xref: UniProtKB:Q8N103 xref: UniProtKB:Q8NI40 xref: UniProtKB:Q96KZ2 xref: UniProtKB:Q96QA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020142 ! TAGAP_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0020752 name: PRP8_HUMAN def: "Pre-mRNA-processing-splicing factor 8" [UniProtKB:Q6P2Q9] synonym: "220 kDa U5 snRNP-specific protein" EXACT [UniProtKB:Q6P2Q9] synonym: "p220" EXACT [UniProtKB:Q6P2Q9] synonym: "PRP8 homolog" EXACT [UniProtKB:Q6P2Q9] synonym: "Splicing factor Prp8" EXACT [UniProtKB:Q6P2Q9] xref: EMBL:AAC61776.1 xref: EMBL:AAH64370.1 xref: EMBL:BAA22563.1 xref: UniProtKB:O14547 xref: UniProtKB:O75965 xref: UniProtKB:Q6P2Q9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008014 ! PRPF8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: transforms_into CCO:B0035471 ! PRP8_HUMAN-Phosphothreonine1318 relationship: transforms_into CCO:B0035472 ! PRP8_HUMAN-Phosphothreonine2042 relationship: transforms_into CCO:B0035473 ! PRP8_HUMAN-Phosphothreonine2064 relationship: transforms_into CCO:B0069554 ! PRP8_HUMAN-Phosphoserine1539 relationship: transforms_into CCO:B0069555 ! PRP8_HUMAN-Phosphoserine2079 [Term] id: CCO:B0020756 name: Q96GK1_HUMAN def: "Sphingosine kinase 1" [UniProtKB:Q96GK1] synonym: "Sphingosine kinase 1, isoform CRA_c" EXACT [UniProtKB:Q96GK1] xref: EMBL:AAH09419.1 xref: EMBL:EAW89393.1 xref: UniProtKB:Q96GK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005660 ! SPHK1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003533 ! D-erythro-sphingosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0020760 name: Q8N632_HUMAN xref: UniProtKB:Q8N632 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003533 ! D-erythro-sphingosine kinase activity relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0020764 name: RGS20_HUMAN def: "Regulator of G-protein signaling 20" [UniProtKB:O76081] synonym: "G(z)GAP" EXACT [UniProtKB:O76081] synonym: "Gz-selective GTPase-activating protein" EXACT [UniProtKB:O76081] synonym: "Regulator of Gz-selective protein signaling 1" EXACT [UniProtKB:O76081] synonym: "RGS20" EXACT [UniProtKB:O76081] xref: EMBL:AAC62009.2 xref: EMBL:AAC62013.1 xref: EMBL:AAH15614.2 xref: EMBL:AAH63490.1 xref: EMBL:AAK54122.1 xref: EMBL:AAK54123.1 xref: EMBL:AAK54124.1 xref: EMBL:AAK54125.1 xref: EMBL:AAL03971.1 xref: EMBL:AAM12654.1 xref: UniProtKB:O76081 xref: UniProtKB:Q96BG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008095 ! RGS20_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0020765 name: RGS21_HUMAN def: "Regulator of G-protein signaling 21" [UniProtKB:Q2M5E4] synonym: "RGS21" EXACT [UniProtKB:Q2M5E4] xref: EMBL:AAT64913.1 xref: UniProtKB:Q2M5E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008096 ! RGS21_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0020766 name: RGS5_HUMAN def: "Regulator of G-protein signaling 5" [UniProtKB:O15539] synonym: "RGS5" EXACT [UniProtKB:O15539] xref: EMBL:AAB84001.1 xref: EMBL:AAD40957.1 xref: EMBL:AAH30059.1 xref: EMBL:AAM12643.1 xref: EMBL:BAA22889.1 xref: EMBL:CAI15095.1 xref: UniProtKB:O15539 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008099 ! RGS5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0020768 name: RGS16_HUMAN def: "Regulator of G-protein signaling 16" [UniProtKB:O15492] synonym: "A28-RGS14P" EXACT [UniProtKB:O15492] synonym: "Retinally abundant regulator of G-protein signaling" EXACT [UniProtKB:O15492] synonym: "RGS-R" EXACT [UniProtKB:O15492] synonym: "RGS16" EXACT [UniProtKB:O15492] xref: EMBL:AAC16912.1 xref: EMBL:AAC39642.1 xref: EMBL:AAC52040.1 xref: EMBL:AAH06243.1 xref: EMBL:AAM12651.1 xref: EMBL:AAP35284.1 xref: EMBL:CAH72419.1 xref: UniProtKB:O15492 xref: UniProtKB:Q5VYN9 xref: UniProtKB:Q99701 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008090 ! RGS16_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0035554 ! RGS16_HUMAN-Phosphotyrosine168 relationship: transforms_into CCO:B0035555 ! RGS16_HUMAN-Phosphotyrosine177 [Term] id: CCO:B0020771 name: RGS3_HUMAN def: "Regulator of G-protein signaling 3" [UniProtKB:P49796] synonym: "RGP3" EXACT [UniProtKB:P49796] synonym: "RGS3" EXACT [UniProtKB:P49796] xref: EMBL:AAC50394.1 xref: EMBL:AAH42555.1 xref: EMBL:AAL68829.1 xref: EMBL:AAM12641.1 xref: EMBL:AAM12655.1 xref: EMBL:AAM33254.1 xref: EMBL:AAM33255.1 xref: EMBL:AAT79495.1 xref: EMBL:BAC11328.1 xref: EMBL:BAC87285.1 xref: EMBL:CAC78977.1 xref: EMBL:CAH70102.1 xref: EMBL:CAH70841.1 xref: EMBL:CAH70843.1 xref: EMBL:CAH73877.1 xref: EMBL:CAH73879.1 xref: UniProtKB:P49796 xref: UniProtKB:Q5VXC1 xref: UniProtKB:Q5VZ05 xref: UniProtKB:Q6ZRM5 xref: UniProtKB:Q8IUQ1 xref: UniProtKB:Q8NC47 xref: UniProtKB:Q8NFN4 xref: UniProtKB:Q8NFN5 xref: UniProtKB:Q8TD59 xref: UniProtKB:Q8TD68 xref: UniProtKB:Q8WXA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008097 ! RGS3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0035566 ! RGS3_HUMAN-Phosphoserine943 relationship: transforms_into CCO:B0035567 ! RGS3_HUMAN-Phosphoserine946 [Term] id: CCO:B0020776 name: RGS19_HUMAN def: "Regulator of G-protein signaling 19" [UniProtKB:P49795] synonym: "G-alpha-interacting protein" EXACT [UniProtKB:P49795] synonym: "GAIP" EXACT [UniProtKB:P49795] synonym: "RGS19" EXACT [UniProtKB:P49795] xref: EMBL:AAH01318.1 xref: EMBL:AAH54337.1 xref: EMBL:AAH63010.1 xref: EMBL:AAM12653.1 xref: EMBL:AAP88806.1 xref: EMBL:AAS94232.1 xref: EMBL:CAA62919.1 xref: EMBL:CAD11902.1 xref: UniProtKB:P49795 xref: UniProtKB:Q53XN0 xref: UniProtKB:Q8TD60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008093 ! RGS19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015967 ! rgs19-gnai2-1 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0035557 ! RGS19_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0035558 ! RGS19_HUMAN-Phosphoserine151 [Term] id: CCO:B0020777 name: RGS13_HUMAN def: "Regulator of G-protein signaling 13" [UniProtKB:O14921] synonym: "RGS13" EXACT [UniProtKB:O14921] xref: EMBL:AAB84000.1 xref: EMBL:AAH16667.1 xref: EMBL:AAH56866.2 xref: EMBL:AAM12649.1 xref: EMBL:AAP35575.1 xref: EMBL:AAS66360.1 xref: EMBL:CAG38769.1 xref: EMBL:CAH71773.1 xref: EMBL:CAI17062.1 xref: UniProtKB:O14921 xref: UniProtKB:Q6PGR2 xref: UniProtKB:Q8TD63 xref: UniProtKB:Q9BX45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008088 ! RGS13_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003112 ! regulator of G-protein signaling activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0002532 ! negative regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0020780 name: RGS1_HUMAN def: "Regulator of G-protein signaling 1" [UniProtKB:Q08116] synonym: "B-cell activation protein BL34" EXACT [UniProtKB:Q08116] synonym: "Early response protein 1R20" EXACT [UniProtKB:Q08116] synonym: "RGS1" EXACT [UniProtKB:Q08116] xref: EMBL:AAB26289.1 xref: EMBL:AAH15510.1 xref: EMBL:AAM12639.1 xref: EMBL:AAP35314.1 xref: EMBL:CAA51826.1 xref: EMBL:CAC19805.1 xref: UniProtKB:Q07918 xref: UniProtKB:Q08116 xref: UniProtKB:Q9H1W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008094 ! RGS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020149 ! rgs1-fundc2 physical interaction relationship: participates_in CCO:I0020435 ! rgs1-map3k12 physical interaction relationship: participates_in CCO:I0020436 ! rgs1-utp14a physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0035559 ! RGS1_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0035560 ! RGS1_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0035561 ! RGS1_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0035562 ! RGS1_HUMAN-Phosphothreonine146 relationship: transforms_into CCO:B0035563 ! RGS1_HUMAN-Phosphothreonine156 relationship: transforms_into CCO:B0035564 ! RGS1_HUMAN-Phosphothreonine167 relationship: transforms_into CCO:B0035565 ! RGS1_HUMAN-Phosphoserine194 [Term] id: CCO:B0020787 name: RGS18_HUMAN def: "Regulator of G-protein signaling 18" [UniProtKB:Q9NS28] synonym: "RGS18" EXACT [UniProtKB:Q9NS28] xref: EMBL:AAF80227.1 xref: EMBL:AAH20632.1 xref: EMBL:AAK58589.1 xref: EMBL:CAH70529.1 xref: EMBL:CAH71160.1 xref: UniProtKB:Q9NS28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008092 ! RGS18_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0003112 ! regulator of G-protein signaling activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0020790 name: RGS8_HUMAN def: "Regulator of G-protein signaling 8" [UniProtKB:P57771] synonym: "RGS8" EXACT [UniProtKB:P57771] xref: EMBL:AAG18443.1 xref: EMBL:AAG45337.1 xref: EMBL:AAH69677.1 xref: EMBL:AAH69718.1 xref: EMBL:AAI03866.1 xref: EMBL:AAI03867.1 xref: EMBL:AAI03868.1 xref: EMBL:CAH72421.1 xref: UniProtKB:P57771 xref: UniProtKB:Q3SYD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008100 ! RGS8_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0020850 name: Q9P1K2_HUMAN def: "PRO1181" [UniProtKB:Q9P1K2] xref: EMBL:AAF71050.1 xref: UniProtKB:Q9P1K2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0020855 name: GTPB1_HUMAN def: "GTP-binding protein 1" [UniProtKB:O00178] synonym: "G-protein 1" EXACT [UniProtKB:O00178] synonym: "GP-1" EXACT [UniProtKB:O00178] synonym: "GP1" EXACT [UniProtKB:O00178] xref: EMBL:AAB51273.1 xref: EMBL:AAH14075.2 xref: EMBL:CAG30387.1 xref: EMBL:CAI21603.2 xref: UniProtKB:O00178 xref: UniProtKB:Q6IC67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007609 ! GTPBP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0034851 ! GTPB1_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0034852 ! GTPB1_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0034853 ! GTPB1_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0034854 ! GTPB1_HUMAN-Phosphoserine47 [Term] id: CCO:B0020873 name: Q6ZTM6_HUMAN def: "cDNA FLJ44504 fis, clone UTERU3001240, highly similar to Adenylate cyclase, type IV (EC 4.6.1.1)" [UniProtKB:Q6ZTM6] synonym: "Adenylate cyclase 4, isoform CRA_d" EXACT [UniProtKB:Q6ZTM6] xref: EMBL:BAC86560.1 xref: EMBL:EAW66028.1 xref: UniProtKB:Q6ZTM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007217 ! ADCY4_human relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0020874 name: ADCY2_HUMAN def: "Adenylate cyclase type 2" [UniProtKB:Q08462] synonym: "Adenylate cyclase type II" EXACT [UniProtKB:Q08462] synonym: "Adenylyl cyclase 2" EXACT [UniProtKB:Q08462] synonym: "ATP pyrophosphate-lyase 2" EXACT [UniProtKB:Q08462] synonym: "EC 4.6.1.1" EXACT [UniProtKB:Q08462] xref: EMBL:AAA64923.1 xref: EMBL:AAI11744.1 xref: EMBL:AAP97285.1 xref: EMBL:BAA83012.1 xref: EMBL:CAA52282.1 xref: UniProtKB:Q08462 xref: UniProtKB:Q2NKL8 xref: UniProtKB:Q9UPU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007216 ! ADCY2_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0020879 name: ADCY7_HUMAN def: "Adenylate cyclase type 7" [UniProtKB:P51828] synonym: "Adenylate cyclase type VII" EXACT [UniProtKB:P51828] synonym: "Adenylyl cyclase 7" EXACT [UniProtKB:P51828] synonym: "ATP pyrophosphate-lyase 7" EXACT [UniProtKB:P51828] synonym: "EC 4.6.1.1" EXACT [UniProtKB:P51828] xref: EMBL:AAI26272.1 xref: EMBL:BAA05021.2 xref: UniProtKB:A0AVA6 xref: UniProtKB:P51828 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007218 ! ADCY7_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0020880 name: ADCY4_HUMAN def: "Adenylate cyclase type 4" [UniProtKB:Q8NFM4] synonym: "Adenylate cyclase type IV" EXACT [UniProtKB:Q8NFM4] synonym: "Adenylyl cyclase 4" EXACT [UniProtKB:Q8NFM4] synonym: "ATP pyrophosphate-lyase 4" EXACT [UniProtKB:Q8NFM4] synonym: "EC 4.6.1.1" EXACT [UniProtKB:Q8NFM4] xref: EMBL:AAI17474.1 xref: EMBL:AAI17476.1 xref: EMBL:AAM94373.1 xref: EMBL:BAB71270.1 xref: UniProtKB:Q17R40 xref: UniProtKB:Q8NFM4 xref: UniProtKB:Q96ML7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007217 ! ADCY4_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0020930 name: GLIS2_HUMAN def: "Zinc finger protein GLIS2" [UniProtKB:Q9BZE0] synonym: "GLI-similar 2" EXACT [UniProtKB:Q9BZE0] synonym: "Neuronal Krueppel-like protein" EXACT [UniProtKB:Q9BZE0] xref: EMBL:AAK00954.1 xref: UniProtKB:Q9BZE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013548 ! GLIS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0043283 ! GLIS2_HUMAN-Phosphoserine245 [Term] id: CCO:B0020932 name: GLIS1_HUMAN def: "Zinc finger protein GLIS1" [UniProtKB:Q8NBF1] synonym: "GLI-similar 1" EXACT [UniProtKB:Q8NBF1] xref: EMBL:AAI01800.1 xref: EMBL:AAI04912.1 xref: EMBL:BAC03494.1 xref: EMBL:BAC04178.1 xref: EMBL:CAH72026.1 xref: EMBL:EAX06734.1 xref: UniProtKB:Q2M3G9 xref: UniProtKB:Q8N9V9 xref: UniProtKB:Q8NBF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007597 ! GLIS1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0020948 name: MP2K3_HUMAN def: "Dual specificity mitogen-activated protein kinase kinase 3" [UniProtKB:P46734] synonym: "EC 2.7.12.2" EXACT [UniProtKB:P46734] synonym: "MAP kinase kinase 3" EXACT [UniProtKB:P46734] synonym: "MAPK/ERK kinase 3" EXACT [UniProtKB:P46734] synonym: "MAPKK 3" EXACT [UniProtKB:P46734] xref: EMBL:AAB40652.1 xref: EMBL:AAB40653.1 xref: EMBL:AAC41718.1 xref: EMBL:AAH32478.1 xref: EMBL:BAA13248.1 xref: UniProtKB:P46734 xref: UniProtKB:Q99441 xref: UniProtKB:Q9UE71 xref: UniProtKB:Q9UE72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011541 ! MAP2K3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015947 ! dyrk1b-map2k3-1 physical interaction relationship: participates_in CCO:I0018649 ! dyrk1b-map2k3-2 phosphorylation relationship: participates_in CCO:I0019382 ! pkn1-map2k3-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039525 ! MP2K3_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0039526 ! MP2K3_HUMAN-Phosphothreonine222 [Term] id: CCO:B0020951 name: MP2K7_HUMAN def: "Dual specificity mitogen-activated protein kinase kinase 7" [UniProtKB:O14733] synonym: "c-Jun N-terminal kinase kinase 2" EXACT [UniProtKB:O14733] synonym: "EC 2.7.12.2" EXACT [UniProtKB:O14733] synonym: "JNK kinase 2" EXACT [UniProtKB:O14733] synonym: "JNK-activating kinase 2" EXACT [UniProtKB:O14733] synonym: "JNKK 2" EXACT [UniProtKB:O14733] synonym: "MAP kinase kinase 7" EXACT [UniProtKB:O14733] synonym: "MAPK/ERK kinase 7" EXACT [UniProtKB:O14733] synonym: "MAPKK 7" EXACT [UniProtKB:O14733] xref: EMBL:AAB63374.1 xref: EMBL:AAB88048.1 xref: EMBL:AAB97813.1 xref: EMBL:AAC16272.1 xref: EMBL:AAC16273.1 xref: EMBL:AAC26142.1 xref: EMBL:AAH38295.1 xref: EMBL:ABE03013.1 xref: UniProtKB:O14648 xref: UniProtKB:O14733 xref: UniProtKB:O14816 xref: UniProtKB:O60452 xref: UniProtKB:O60453 xref: UniProtKB:Q1PG43 xref: UniProtKB:Q8IY10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011543 ! MAP2K7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0019244 ! trib3-map2k7-1 physical interaction relationship: participates_in CCO:I0020513 ! arr3-map2k7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003090 ! stress-activated MAPK cascade [Term] id: CCO:B0020975 name: T2FB_HUMAN def: "General transcription factor IIF subunit 2" [UniProtKB:P13984] synonym: "ATP-dependent helicase GTF2F2" EXACT [UniProtKB:P13984] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P13984] synonym: "TFIIF-beta" EXACT [UniProtKB:P13984] synonym: "Transcription initiation factor IIF subunit beta" EXACT [UniProtKB:P13984] synonym: "Transcription initiation factor RAP30" EXACT [UniProtKB:P13984] xref: EMBL:AAH01771.1 xref: EMBL:AAV38332.1 xref: EMBL:BAF84234.1 xref: EMBL:CAA34775.1 xref: EMBL:CAA42419.1 xref: EMBL:CAH72032.1 xref: EMBL:CAH72459.1 xref: EMBL:EAX08728.1 xref: UniProtKB:A6NNS5 xref: UniProtKB:P13984 xref: UniProtKB:Q5W0H3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020092 ! GTF2F2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018703 ! gtf2f1-gtf2f2-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071071 ! T2FB_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0071072 ! T2FB_HUMAN-Phosphoserine248 [Term] id: CCO:B0020984 name: U520_HUMAN def: "U5 small nuclear ribonucleoprotein 200 kDa helicase" [UniProtKB:O75643] synonym: "Activating signal cointegrator 1 complex subunit 3-like 1" EXACT [UniProtKB:O75643] synonym: "BRR2 homolog" EXACT [UniProtKB:O75643] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O75643] synonym: "U5 snRNP-specific 200 kDa protein" EXACT [UniProtKB:O75643] synonym: "U5-200KD" EXACT [UniProtKB:O75643] xref: EMBL:AAH07577.1 xref: EMBL:AAH65924.1 xref: EMBL:AAS78571.1 xref: EMBL:BAA34508.2 xref: EMBL:BAB14906.1 xref: EMBL:BAC03499.1 xref: EMBL:CAA94089.1 xref: UniProtKB:O75643 xref: UniProtKB:O94884 xref: UniProtKB:Q6NZY0 xref: UniProtKB:Q6PX59 xref: UniProtKB:Q8NBE6 xref: UniProtKB:Q96IF2 xref: UniProtKB:Q9H7S0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008329 ! ASCC3L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: transforms_into CCO:B0035818 ! U520_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0035819 ! U520_HUMAN-Phosphoserine756 relationship: transforms_into CCO:B0035820 ! U520_HUMAN-Phosphoserine1056 relationship: transforms_into CCO:B0071656 ! U520_HUMAN-Phosphotyrosine922 relationship: transforms_into CCO:B0071657 ! U520_HUMAN-Phosphotyrosine924 relationship: transforms_into CCO:B0071658 ! U520_HUMAN-Phosphotyrosine926 [Term] id: CCO:B0020998 name: HELC1_HUMAN def: "Activating signal cointegrator 1 complex subunit 3" [UniProtKB:Q8N3C0] synonym: "ASC-1 complex subunit p200" EXACT [UniProtKB:Q8N3C0] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q8N3C0] synonym: "Helicase, ATP binding 1" EXACT [UniProtKB:Q8N3C0] synonym: "Trip4 complex subunit p200" EXACT [UniProtKB:Q8N3C0] xref: EMBL:AAG45474.1 xref: EMBL:CAA11679.1 xref: EMBL:CAD39122.1 xref: EMBL:CAH73862.1 xref: EMBL:CAI16190.1 xref: EMBL:CAI19454.1 xref: EMBL:CAI19627.1 xref: EMBL:CAI21439.1 xref: UniProtKB:O43738 xref: UniProtKB:Q5VTN2 xref: UniProtKB:Q8N3C0 xref: UniProtKB:Q9H1I9 xref: UniProtKB:Q9NTR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007616 ! ASCC3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021009 name: Q9UHS4_HUMAN def: "PRO2042" [UniProtKB:Q9UHS4] xref: EMBL:AAF22033.1 xref: UniProtKB:Q9UHS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0021015 name: Q5TBX5_HUMAN def: "Protein kinase N2" [UniProtKB:Q5TBX5] xref: EMBL:CAI23273.1 xref: UniProtKB:Q5TBX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007981 ! PKN2_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0021018 name: PKN3_HUMAN def: "Serine/threonine-protein kinase N3" [UniProtKB:Q6P5Z2] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q6P5Z2] synonym: "Protein kinase PKN-beta" EXACT [UniProtKB:Q6P5Z2] synonym: "Protein-kinase C-related kinase 3" EXACT [UniProtKB:Q6P5Z2] xref: EMBL:AAH62558.1 xref: EMBL:BAA85625.1 xref: EMBL:CAI15401.1 xref: UniProtKB:Q6P5Z2 xref: UniProtKB:Q9UM03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007982 ! PKN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035392 ! PKN3_HUMAN-Phosphoserine544 relationship: transforms_into CCO:B0035393 ! PKN3_HUMAN-Phosphothreonine550 relationship: transforms_into CCO:B0035394 ! PKN3_HUMAN-Phosphothreonine718 relationship: transforms_into CCO:B0035395 ! PKN3_HUMAN-Phosphothreonine860 relationship: transforms_into CCO:B0069372 ! PKN3_HUMAN-Phosphoserine548 [Term] id: CCO:B0021020 name: PKN2_HUMAN def: "Serine/threonine-protein kinase N2" [UniProtKB:Q16513] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q16513] synonym: "Protein kinase C-like 2" EXACT [UniProtKB:Q16513] synonym: "Protein-kinase C-related kinase 2" EXACT [UniProtKB:Q16513] xref: EMBL:AAB33346.1 xref: EMBL:AAC50208.1 xref: EMBL:CAI23271.1 xref: UniProtKB:Q16513 xref: UniProtKB:Q9H1W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007981 ! PKN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035380 ! PKN2_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0035381 ! PKN2_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0035382 ! PKN2_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0035383 ! PKN2_HUMAN-Phosphoserine360 relationship: transforms_into CCO:B0035384 ! PKN2_HUMAN-Phosphoserine531 relationship: transforms_into CCO:B0035385 ! PKN2_HUMAN-Phosphoserine535 relationship: transforms_into CCO:B0035386 ! PKN2_HUMAN-Phosphoserine559 relationship: transforms_into CCO:B0035387 ! PKN2_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0035388 ! PKN2_HUMAN-Phosphoserine582 relationship: transforms_into CCO:B0035389 ! PKN2_HUMAN-Phosphoserine583 relationship: transforms_into CCO:B0035390 ! PKN2_HUMAN-Phosphothreonine816 relationship: transforms_into CCO:B0035391 ! PKN2_HUMAN-Phosphothreonine958 relationship: transforms_into CCO:B0069366 ! PKN2_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0069367 ! PKN2_HUMAN-Phosphothreonine121 relationship: transforms_into CCO:B0069368 ! PKN2_HUMAN-Phosphothreonine124 relationship: transforms_into CCO:B0069369 ! PKN2_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0069370 ! PKN2_HUMAN-Phosphothreonine628 relationship: transforms_into CCO:B0069371 ! PKN2_HUMAN-Phosphoserine631 [Term] id: CCO:B0021030 name: CHD1_HUMAN def: "Chromodomain-helicase-DNA-binding protein 1" [UniProtKB:O14646] synonym: "ATP-dependent helicase CHD1" EXACT [UniProtKB:O14646] synonym: "CHD-1" EXACT [UniProtKB:O14646] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O14646] xref: EMBL:AAB87381.1 xref: UniProtKB:O14646 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007386 ! CHD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0034654 ! CHD1_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0034655 ! CHD1_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0034656 ! CHD1_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0034657 ! CHD1_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0034658 ! CHD1_HUMAN-Phosphotyrosine1068 relationship: transforms_into CCO:B0034659 ! CHD1_HUMAN-Phosphoserine1353 relationship: transforms_into CCO:B0034660 ! CHD1_HUMAN-Phosphoserine1355 relationship: transforms_into CCO:B0034661 ! CHD1_HUMAN-Phosphoserine1356 relationship: transforms_into CCO:B0034662 ! CHD1_HUMAN-Phosphoserine1360 [Term] id: CCO:B0021032 name: CHD2_HUMAN def: "Chromodomain-helicase-DNA-binding protein 2" [UniProtKB:O14647] synonym: "ATP-dependent helicase CHD2" EXACT [UniProtKB:O14647] synonym: "CHD-2" EXACT [UniProtKB:O14647] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O14647] xref: EMBL:AAB87382.1 xref: UniProtKB:O14647 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007387 ! CHD2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0021069 name: EF1D_HUMAN def: "Elongation factor 1-delta" [UniProtKB:P29692] synonym: "Antigen NY-CO-4" EXACT [UniProtKB:P29692] synonym: "EF-1-delta" EXACT [UniProtKB:P29692] xref: EMBL:AAH09907.1 xref: EMBL:AAH12819.1 xref: EMBL:AAH62535.1 xref: EMBL:CAA79716.1 xref: UniProtKB:P29692 xref: UniProtKB:Q969J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017661 ! EEF1D_human relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000419 ! eukaryotic translation elongation factor 1 complex relationship: participates_in CCO:I0019524 ! eef1d-eef1g physical interaction relationship: participates_in CCO:I0019525 ! eef1g-eef1d physical interaction relationship: participates_in CCO:I0019527 ! ascc2-eef1d physical interaction relationship: participates_in CCO:I0019586 ! eef1d-crmp1 physical interaction relationship: participates_in CCO:I0019710 ! eef1d-eef1d physical interaction relationship: participates_in CCO:I0019929 ! fra10ac1-eef1d physical interaction relationship: participates_in CCO:I0020298 ! eef1d-cd48 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0064924 ! EF1D_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064925 ! EF1D_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0064926 ! EF1D_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0064927 ! EF1D_HUMAN-Phosphothreonine129 relationship: transforms_into CCO:B0064928 ! EF1D_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0064929 ! EF1D_HUMAN-Phosphothreonine147 relationship: transforms_into CCO:B0064930 ! EF1D_HUMAN-Phosphoserine162 [Term] id: CCO:B0021083 name: Q96I38_HUMAN def: "EEF1D protein" [UniProtKB:Q96I38] synonym: "Eukaryotic translation elongation factor 1 delta (Guanine nucleotide exchange protein)" EXACT [UniProtKB:Q96I38] synonym: "Eukaryotic translation elongation factor 1 delta (Guanine nucleotide exchange protein), isoform CRA_b" EXACT [UniProtKB:Q96I38] xref: EMBL:AAH07847.1 xref: EMBL:AAP35906.1 xref: EMBL:EAW82228.1 xref: UniProtKB:Q96I38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017661 ! EEF1D_human relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000419 ! eukaryotic translation elongation factor 1 complex relationship: participates_in CCO:I0015443 ! eef1d-eef1g-1 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0021108 name: MK14_HUMAN def: "Mitogen-activated protein kinase 14" [UniProtKB:Q16539] synonym: "CSAID-binding protein" EXACT [UniProtKB:Q16539] synonym: "CSBP" EXACT [UniProtKB:Q16539] synonym: "Cytokine suppressive anti-inflammatory drug-binding protein" EXACT [UniProtKB:Q16539] synonym: "EC 2.7.11.24" EXACT [UniProtKB:Q16539] synonym: "MAP kinase MXI2" EXACT [UniProtKB:Q16539] synonym: "MAP kinase p38 alpha" EXACT [UniProtKB:Q16539] synonym: "MAX-interacting protein 2" EXACT [UniProtKB:Q16539] synonym: "Mitogen-activated protein kinase p38 alpha" EXACT [UniProtKB:Q16539] synonym: "SAPK2A" EXACT [UniProtKB:Q16539] xref: EMBL:AAA57455.1 xref: EMBL:AAA57456.1 xref: EMBL:AAA74301.1 xref: EMBL:AAC50329.1 xref: EMBL:AAF36770.1 xref: EMBL:AAH00092.1 xref: EMBL:AAH31574.1 xref: EMBL:AAP35579.1 xref: EMBL:ABY87549.1 xref: EMBL:BAB85654.1 xref: EMBL:BAF84398.1 xref: EMBL:CAG38743.1 xref: EMBL:EAX03869.1 xref: UniProtKB:A6ZJ92 xref: UniProtKB:A8K6P4 xref: UniProtKB:B0LPH0 xref: UniProtKB:O60776 xref: UniProtKB:Q13083 xref: UniProtKB:Q14084 xref: UniProtKB:Q16539 xref: UniProtKB:Q8TDX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007825 ! MAPK14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015169 ! mapk14-zfp36l1 physical interaction relationship: participates_in CCO:I0017383 ! mapk14-rps6ka4 physical interaction relationship: participates_in CCO:I0017404 ! fam48a-mapk14 physical interaction relationship: participates_in CCO:I0017646 ! rps6ka4-mapk14 physical interaction relationship: participates_in CCO:I0018246 ! gstp1-mapk13 physical interaction relationship: participates_in CCO:I0019299 ! fam48a-mapk14-1 physical interaction relationship: participates_in CCO:I0019300 ! fam48a-mapk14-2 physical interaction relationship: participates_in CCO:I0019381 ! pkn1-mapk14-1 physical interaction relationship: participates_in CCO:I0019427 ! mapk14-zfp36l1-1 physical interaction relationship: participates_in CCO:I0020553 ! fkbp8-mapk14 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0035197 ! MK14_HUMAN-Phosphothreonine180 relationship: transforms_into CCO:B0035198 ! MK14_HUMAN-Phosphotyrosine182 relationship: transforms_into CCO:B0035199 ! MK14_HUMAN-Phosphothreonine263 [Term] id: CCO:B0021138 name: PDXK_HUMAN def: "Pyridoxal kinase" [UniProtKB:O00764] synonym: "EC 2.7.1.35" EXACT [UniProtKB:O00764] synonym: "Pyridoxine kinase" EXACT [UniProtKB:O00764] xref: EMBL:AAC51233.1 xref: EMBL:AAH00123.1 xref: EMBL:AAH05825.1 xref: EMBL:AAP73047.1 xref: EMBL:BAA95540.1 xref: UniProtKB:O00764 xref: UniProtKB:Q7Z2Y0 xref: UniProtKB:Q9BS02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007962 ! PDXK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0035357 ! PDXK_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0021154 name: Q6PIQ2_HUMAN def: "ZNF197 protein" [UniProtKB:Q6PIQ2] xref: EMBL:AAH31209.1 xref: UniProtKB:Q6PIQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020650 ! ZNF197_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021155 name: Q86VG0_HUMAN def: "PVHL-associated KRAB domain-containing protein" [UniProtKB:Q86VG0] xref: EMBL:AAL79677.1 xref: UniProtKB:Q86VG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021226 ! VHLAK_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021156 name: SCND2_HUMAN def: "SCAN domain-containing protein 2" [UniProtKB:Q9GZW5] xref: EMBL:AAG33966.1 xref: EMBL:AAG34567.1 xref: EMBL:AAH11547.1 xref: EMBL:AAH12929.1 xref: EMBL:AAH63836.1 xref: EMBL:BAB14268.1 xref: UniProtKB:Q9GZW5 xref: UniProtKB:Q9H9G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008167 ! SCAND2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035624 ! SCND2_HUMAN-Phosphoserine260 [Term] id: CCO:B0021159 name: Q86V93_HUMAN def: "LOC100128510 protein" [UniProtKB:Q86V93] synonym: "Zinc finger protein 75a, isoform CRA_d" EXACT [UniProtKB:Q86V93] xref: EMBL:AAH51366.1 xref: EMBL:EAW85377.1 xref: UniProtKB:Q86V93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021225 ! LOC100128510_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021160 name: Q07644_HUMAN def: "Polypeptide" [UniProtKB:Q07644] xref: EMBL:CAA79814.1 xref: UniProtKB:Q07644 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021184 name: TERA_HUMAN def: "Transitional endoplasmic reticulum ATPase" [UniProtKB:P55072] synonym: "15S Mg(2+)-ATPase p97 subunit" EXACT [UniProtKB:P55072] synonym: "TER ATPase" EXACT [UniProtKB:P55072] synonym: "Valosin-containing protein" EXACT [UniProtKB:P55072] synonym: "VCP" EXACT [UniProtKB:P55072] xref: EMBL:AAC07984.1 xref: EMBL:AAD43016.1 xref: EMBL:CAA94809.1 xref: UniProtKB:P55072 xref: UniProtKB:Q969G7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008281 ! VCP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007181 ! snf1l2-2aab-1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016379 ! nfkbia-vcp physical interaction relationship: participates_in CCO:I0016400 ! nfkbib-vcp physical interaction relationship: participates_in CCO:I0016426 ! nfkbie-vcp physical interaction relationship: participates_in CCO:I0016706 ! map3k3-vcp physical interaction relationship: participates_in CCO:I0017142 ! traf6-vcp physical interaction relationship: participates_in CCO:I0018561 ! rma1-cftr-3 physical interaction relationship: participates_in CCO:I0018839 ! wrn-vcp-1 physical interaction relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0035769 ! TERA_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035770 ! TERA_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0035771 ! TERA_HUMAN-Phosphoserine784 relationship: transforms_into CCO:B0035772 ! TERA_HUMAN-Phosphotyrosine805 relationship: transforms_into CCO:B0040661 ! TERA_HUMAN-Phosphoserine702 relationship: transforms_into CCO:B0040662 ! TERA_HUMAN-Phosphoserine705 [Term] id: CCO:B0021202 name: A2A3C6_HUMAN def: "Brain-specific angiogenesis inhibitor 2" [UniProtKB:A2A3C6] xref: EMBL:CAM12879.1 xref: UniProtKB:A2A3C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017120 ! BAI2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003198 ! brain-specific angiogenesis inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0021203 name: A2A3C1_HUMAN def: "Brain-specific angiogenesis inhibitor 2" [UniProtKB:A2A3C1] xref: EMBL:CAM12874.1 xref: UniProtKB:A2A3C1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017120 ! BAI2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0021206 name: A2A3C4_HUMAN def: "Brain-specific angiogenesis inhibitor 2" [UniProtKB:A2A3C4] xref: EMBL:CAM12877.1 xref: UniProtKB:A2A3C4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017120 ! BAI2_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003198 ! brain-specific angiogenesis inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0021208 name: A2A3C2_HUMAN def: "Brain-specific angiogenesis inhibitor 2" [UniProtKB:A2A3C2] xref: EMBL:CAM12875.1 xref: UniProtKB:A2A3C2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017120 ! BAI2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003198 ! brain-specific angiogenesis inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0021209 name: A2A3C3_HUMAN def: "Brain-specific angiogenesis inhibitor 2" [UniProtKB:A2A3C3] xref: EMBL:CAM12876.1 xref: UniProtKB:A2A3C3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017120 ! BAI2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0021210 name: BAI2_HUMAN def: "Brain-specific angiogenesis inhibitor 2 precursor" [UniProtKB:O60241] xref: EMBL:BAA25362.1 xref: EMBL:BAC05874.1 xref: EMBL:CAI16890.1 xref: UniProtKB:O60241 xref: UniProtKB:Q5T6K0 xref: UniProtKB:Q8NGW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017120 ! BAI2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003198 ! brain-specific angiogenesis inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0063707 ! BAI2_HUMAN-Phosphotyrosine1339 [Term] id: CCO:B0021241 name: TF2LX_HUMAN def: "Homeobox protein TGIF2LX" [UniProtKB:Q8IUE1] synonym: "TGF(beta)induced transcription factor 2-like protein" EXACT [UniProtKB:Q8IUE1] synonym: "TGFB-induced factor 2-like protein, X-linked" EXACT [UniProtKB:Q8IUE1] synonym: "TGIF-like on the X" EXACT [UniProtKB:Q8IUE1] xref: EMBL:AAI17399.1 xref: EMBL:AAI17401.1 xref: EMBL:AAM18073.1 xref: EMBL:CAD20750.1 xref: EMBL:CAI41575.1 xref: UniProtKB:Q5JRM9 xref: UniProtKB:Q8IUE1 xref: UniProtKB:Q8TD48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020241 ! TGIF2LX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0021248 name: Q3ZCM9_HUMAN def: "TGIF2LX protein" [UniProtKB:Q3ZCM9] xref: EMBL:AAI01145.1 xref: EMBL:AAI01146.1 xref: UniProtKB:Q3ZCM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020241 ! TGIF2LX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0021260 name: TF2LY_HUMAN def: "Homeobox protein TGIF2LY" [UniProtKB:Q8IUE0] synonym: "TGF(beta)induced transcription factor 2-like protein" EXACT [UniProtKB:Q8IUE0] synonym: "TGFB-induced factor 2-like protein, Y-linked" EXACT [UniProtKB:Q8IUE0] synonym: "TGIF-like on the Y" EXACT [UniProtKB:Q8IUE0] xref: EMBL:AAK13475.1 xref: EMBL:CAD20751.1 xref: UniProtKB:Q8IUE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020242 ! TGIF2LY_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0021266 name: TGIF2_HUMAN def: "Homeobox protein TGIF2" [UniProtKB:Q9GZN2] synonym: "5'-TG-3'-interacting factor 2" EXACT [UniProtKB:Q9GZN2] synonym: "TGF(beta)-induced transcription factor 2" EXACT [UniProtKB:Q9GZN2] synonym: "TGFB-induced factor 2" EXACT [UniProtKB:Q9GZN2] xref: EMBL:AAH06549.1 xref: EMBL:AAH12816.1 xref: EMBL:BAB16424.1 xref: EMBL:BAC11216.1 xref: EMBL:CAB75368.1 xref: UniProtKB:Q9GZN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008286 ! TGIF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0035777 ! TGIF2_HUMAN-Phosphothreonine182 relationship: transforms_into CCO:B0035778 ! TGIF2_HUMAN-Phosphothreonine186 [Term] id: CCO:B0021291 name: RALY_HUMAN def: "RNA-binding protein Raly" [UniProtKB:Q9UKM9] synonym: "Autoantigen p542" EXACT [UniProtKB:Q9UKM9] synonym: "Heterogeneous nuclear ribonucleoprotein C-like 2" EXACT [UniProtKB:Q9UKM9] synonym: "hnRNP associated with lethal yellow homolog" EXACT [UniProtKB:Q9UKM9] synonym: "hnRNP core protein C-like 2" EXACT [UniProtKB:Q9UKM9] xref: EMBL:AAC28898.1 xref: EMBL:AAF04487.1 xref: EMBL:AAI05019.1 xref: EMBL:CAB43742.1 xref: EMBL:CAI22150.1 xref: UniProtKB:Q14621 xref: UniProtKB:Q2M365 xref: UniProtKB:Q5QPL8 xref: UniProtKB:Q9BQX6 xref: UniProtKB:Q9UJE3 xref: UniProtKB:Q9UKM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008052 ! RALY_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020646 ! raly-pik3cd physical interaction relationship: transforms_into CCO:B0035500 ! RALY_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0035501 ! RALY_HUMAN-Phosphothreonine262 relationship: transforms_into CCO:B0035502 ! RALY_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0035503 ! RALY_HUMAN-Phosphothreonine286 relationship: transforms_into CCO:B0035504 ! RALY_HUMAN-Phosphoserine288 relationship: transforms_into CCO:B0035505 ! RALY_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0035506 ! RALY_HUMAN-Phosphothreonine298 [Term] id: CCO:B0021303 name: ZFAN6_HUMAN def: "AN1-type zinc finger protein 6" [UniProtKB:Q6FIF0] synonym: "Associated with PRK1 protein" EXACT [UniProtKB:Q6FIF0] synonym: "Zinc finger A20 domain-containing protein 3" EXACT [UniProtKB:Q6FIF0] xref: EMBL:AAD17528.1 xref: EMBL:AAG44674.1 xref: EMBL:AAH05283.1 xref: EMBL:CAB66533.1 xref: EMBL:CAC14876.1 xref: EMBL:CAG38507.1 xref: UniProtKB:O95792 xref: UniProtKB:Q6FIF0 xref: UniProtKB:Q9BQF7 xref: UniProtKB:Q9GZY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008365 ! ZFAND6_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0021316 name: Q9C054_HUMAN def: "Tumor protein D52-like 2" [UniProtKB:Q9C054] synonym: "cDNA FLJ78407, highly similar to Homo sapiens tumor protein D52-like 1 (TPD52L1), transcript variant 4, mRNA" EXACT [UniProtKB:Q9C054] synonym: "Tumor protein D52-like 1" EXACT [UniProtKB:Q9C054] xref: EMBL:AAG49634.1 xref: EMBL:BAF84555.1 xref: EMBL:CAI19648.1 xref: EMBL:CAI23003.1 xref: UniProtKB:Q9C054 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008948 ! TPD52L2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade [Term] id: CCO:B0021337 name: KAP1_HUMAN def: "cAMP-dependent protein kinase type I-beta regulatory subunit" [UniProtKB:P31321] xref: EMBL:AAC37564.1 xref: UniProtKB:P31321 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007717 ! PRKAR1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0034960 ! KAP1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0034961 ! KAP1_HUMAN-Nitrated tyrosine21 relationship: transforms_into CCO:B0067258 ! KAP1_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0067259 ! KAP1_HUMAN-Phosphoserine83 [Term] id: CCO:B0021338 name: Q8N422_HUMAN def: "PRKAR1B protein" [UniProtKB:Q8N422] synonym: "Protein kinase, cAMP-dependent, regulatory, type I, beta" EXACT [UniProtKB:Q8N422] xref: EMBL:AAH26734.1 xref: EMBL:AAH36828.2 xref: UniProtKB:Q8N422 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007717 ! PRKAR1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0021340 name: CHSP1_HUMAN def: "Calcium-regulated heat stable protein 1" [UniProtKB:Q9Y2V2] synonym: "Calcium-regulated heat-stable protein of 24 kDa" EXACT [UniProtKB:Q9Y2V2] synonym: "CRHSP-24" EXACT [UniProtKB:Q9Y2V2] xref: EMBL:AAD25021.1 xref: EMBL:AAH03366.1 xref: EMBL:AAI08284.1 xref: UniProtKB:Q2YDX5 xref: UniProtKB:Q9BQ53 xref: UniProtKB:Q9Y2V2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011294 ! CARHSP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020267 ! carhsp1-stc2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0039355 ! CHSP1_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0039356 ! CHSP1_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0039357 ! CHSP1_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0039358 ! CHSP1_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0052328 ! CHSP1_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0052329 ! CHSP1_HUMAN-Phosphoserine147 [Term] id: CCO:B0021341 name: CSDC2_HUMAN def: "Cold shock domain-containing protein C2" [UniProtKB:Q9Y534] synonym: "RNA-binding protein PIPPin" EXACT [UniProtKB:Q9Y534] xref: EMBL:AAH67113.1 xref: EMBL:BAA84704.1 xref: EMBL:CAB46024.1 xref: EMBL:CAD39079.2 xref: EMBL:CAG30343.1 xref: UniProtKB:Q8ND37 xref: UniProtKB:Q9Y534 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011329 ! CSDC2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021348 name: Q15959_HUMAN def: "PML protein" [UniProtKB:Q15959] xref: EMBL:AAB19601.2 xref: UniProtKB:Q15959 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005344 ! PML_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016136 ! plzf-pml-3 direct interaction relationship: participates_in CCO:I0016137 ! plzf-pml-4 direct interaction relationship: participates_in CCO:I0017892 ! plzf-pml-5 physical interaction relationship: participates_in CCO:I0017893 ! plzf-pml-7 physical interaction relationship: participates_in CCO:I0018078 ! pml-plzf-1 colocalization relationship: participates_in CCO:I0018341 ! plzf-pml-1 physical interaction relationship: participates_in CCO:I0018346 ! pml-plzf-2 colocalization relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0021417 name: CALRL_HUMAN def: "Calcitonin gene-related peptide type 1 receptor precursor" [UniProtKB:Q16602] synonym: "Calcitonin receptor-like receptor" EXACT [UniProtKB:Q16602] synonym: "CGRP type 1 receptor" EXACT [UniProtKB:Q16602] xref: EMBL:AAA62158.1 xref: EMBL:AAC41994.1 xref: EMBL:AAQ91332.1 xref: UniProtKB:Q16602 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017219 ! CALCRL_human relationship: has_function CCO:F0000185 ! calcitonin gene-related polypeptide receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001290 ! calcitonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018093 ! calcrl-ramp1-1 colocalization relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation [Term] id: CCO:B0021419 name: A4D1G6_HUMAN def: "Calcitonin receptor (Calcitonin receptor, isoform CRA_b) (cDNA, FLJ94649, Homo sapiens calcitonin receptor (CALCR), mRNA)" [UniProtKB:A4D1G6] xref: EMBL:BAG36708.1 xref: EMBL:EAL24142.1 xref: EMBL:EAW76814.1 xref: UniProtKB:A4D1G6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017217 ! CALCR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001290 ! calcitonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0021425 name: PUR2_HUMAN def: "Trifunctional purine biosynthetic protein adenosine-3" [UniProtKB:P22102] xref: EMBL:AAA60077.1 xref: EMBL:AAB70812.1 xref: EMBL:AAH38958.1 xref: EMBL:CAA38119.1 xref: UniProtKB:O14659 xref: UniProtKB:P22102 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013119 ! GART_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016556 ! ikbkg-gart physical interaction relationship: transforms_into CCO:B0040650 ! PUR2_HUMAN-Phosphotyrosine348 [Term] id: CCO:B0021435 name: ATF4_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-4" [UniProtKB:P18848] synonym: "Activating transcription factor 4" EXACT [UniProtKB:P18848] synonym: "CREB2" EXACT [UniProtKB:P18848] synonym: "Cyclic AMP response element-binding protein 2" EXACT [UniProtKB:P18848] synonym: "DNA-binding protein TAXREB67" EXACT [UniProtKB:P18848] xref: EMBL:AAA52071.1 xref: EMBL:AAH08090.1 xref: EMBL:AAH11994.1 xref: EMBL:AAH24775.1 xref: EMBL:AAH73990.1 xref: EMBL:BAA14234.1 xref: EMBL:CAB45284.1 xref: UniProtKB:P18848 xref: UniProtKB:Q9UH31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006035 ! ATF4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_function CCO:F0008016 ! GABA receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0016248 ! trib3-atf4-3 physical interaction relationship: participates_in CCO:I0018007 ! trib3-atf4-4 physical interaction relationship: participates_in CCO:I0018366 ! disc1-atf4-1 physical interaction relationship: participates_in CCO:I0018544 ! disc1-atf4 physical interaction relationship: participates_in CCO:I0019295 ! disc1-atf4-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0021450 name: ADR2_HUMAN def: "Adiponectin receptor protein 2" [UniProtKB:Q86V24] synonym: "Progestin and adipoQ receptor family member II" EXACT [UniProtKB:Q86V24] xref: EMBL:AAH51858.1 xref: EMBL:BAB15062.1 xref: EMBL:BAC86881.1 xref: EMBL:BAC87473.1 xref: UniProtKB:Q86V24 xref: UniProtKB:Q9H737 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016922 ! ADIPOR2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0005682 ! hormone binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0021461 name: ADR1_HUMAN def: "Adiponectin receptor protein 1" [UniProtKB:Q96A54] synonym: "Progestin and adipoQ receptor family member I" EXACT [UniProtKB:Q96A54] xref: EMBL:AAD34040.1 xref: EMBL:AAH01594.1 xref: EMBL:AAH10743.1 xref: UniProtKB:Q96A54 xref: UniProtKB:Q9Y360 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016921 ! ADIPOR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0005682 ! hormone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0021495 name: Q96BT2_HUMAN def: "ARP3 actin-related protein 3 homolog B (Yeast)" [UniProtKB:Q96BT2] xref: EMBL:AAH15207.1 xref: UniProtKB:Q96BT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008904 ! ACTR3B_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0021497 name: Q59GD5_HUMAN def: "Actin-related protein 3-beta variant" [UniProtKB:Q59GD5] xref: EMBL:BAD92411.1 xref: UniProtKB:Q59GD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0021502 name: ARP3_HUMAN def: "Actin-related protein 3" [UniProtKB:P61158] synonym: "Actin-like protein 3" EXACT [UniProtKB:P61158] xref: EMBL:AAB64188.1 xref: EMBL:AAD51904.1 xref: EMBL:AAH44590.1 xref: UniProtKB:P32391 xref: UniProtKB:P61158 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007266 ! ACTR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0018502 ! wasp-arp2-1 physical interaction relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: transforms_into CCO:B0034567 ! ARP3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0034568 ! ARP3_HUMAN-Phosphotyrosine231 relationship: transforms_into CCO:B0034569 ! ARP3_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0063610 ! ARP3_HUMAN-Phosphotyrosine16 relationship: transforms_into CCO:B0063611 ! ARP3_HUMAN-Phosphotyrosine202 [Term] id: CCO:B0021504 name: Q7Z526_HUMAN xref: UniProtKB:Q7Z526 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0021560 name: PSMD3_HUMAN def: "26S proteasome non-ATPase regulatory subunit 3" [UniProtKB:O43242] synonym: "26S proteasome regulatory subunit S3" EXACT [UniProtKB:O43242] synonym: "Proteasome subunit p58" EXACT [UniProtKB:O43242] xref: EMBL:AAH00074.1 xref: EMBL:AAH04859.1 xref: EMBL:AAH12302.1 xref: EMBL:AAH20518.1 xref: EMBL:AAH25686.1 xref: EMBL:AAP35881.1 xref: EMBL:BAA23651.1 xref: UniProtKB:O43242 xref: UniProtKB:Q96EI2 xref: UniProtKB:Q9BQA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008033 ! PSMD3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008718 ! traf6-psmd3 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0021588 name: PRUN2_HUMAN def: "Protein prune homolog 2" [UniProtKB:Q8WUY3] xref: EMBL:AAH19095.1 xref: EMBL:CAI16084.1 xref: EMBL:CAI16085.1 xref: UniProtKB:Q5T304 xref: UniProtKB:Q8WUY3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008016 ! PRUNE2_human relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015081 ! c9orf65-ewsr1 physical interaction [Term] id: CCO:B0021644 name: K2C4_HUMAN def: "Keratin, type II cytoskeletal 4" [UniProtKB:P19013] synonym: "CK-4" EXACT [UniProtKB:P19013] synonym: "Cytokeratin-4" EXACT [UniProtKB:P19013] synonym: "K4" EXACT [UniProtKB:P19013] synonym: "Keratin-4" EXACT [UniProtKB:P19013] xref: EMBL:AAH03630.2 xref: EMBL:AAH42174.1 xref: EMBL:AAL14196.1 xref: EMBL:CAA30534.1 xref: EMBL:CAA43362.1 xref: EMBL:CAA47914.1 xref: UniProtKB:P19013 xref: UniProtKB:Q6GTR8 xref: UniProtKB:Q96LA7 xref: UniProtKB:Q9BTL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007698 ! KRT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: transforms_into CCO:B0034948 ! K2C4_HUMAN-Phosphoserine51 [Term] id: CCO:B0021657 name: K22E_HUMAN def: "Keratin, type II cytoskeletal 2 epidermal" [UniProtKB:P35908] synonym: "CK 2e" EXACT [UniProtKB:P35908] synonym: "Cytokeratin-2e" EXACT [UniProtKB:P35908] synonym: "K2e" EXACT [UniProtKB:P35908] synonym: "keratin-2" EXACT [UniProtKB:P35908] xref: EMBL:AAB81946.1 xref: EMBL:AAC83410.1 xref: EMBL:AAH96294.1 xref: EMBL:AAH99643.1 xref: EMBL:AAH99644.1 xref: UniProtKB:P35908 xref: UniProtKB:Q4VAQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007694 ! KRT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002248 ! keratinocyte proliferation relationship: transforms_into CCO:B0034943 ! K22E_HUMAN-Phosphoserine62 [Term] id: CCO:B0021658 name: NDUS6_HUMAN def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial precursor" [UniProtKB:O75380] synonym: "CI-13kD-A" EXACT [UniProtKB:O75380] synonym: "Complex I-13kD-A" EXACT [UniProtKB:O75380] synonym: "NADH-ubiquinone oxidoreductase 13 kDa-A subunit" EXACT [UniProtKB:O75380] xref: EMBL:AAC27799.1 xref: EMBL:AAH38664.1 xref: EMBL:AAH46155.1 xref: UniProtKB:O75380 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022439 ! NDUFS6_human relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020314 ! fgfr3-ndufs6 physical interaction relationship: participates_in CCO:I0020353 ! kcnh2-ndufs6 physical interaction [Term] id: CCO:B0021669 name: DUS2_HUMAN def: "Dual specificity protein phosphatase 2" [UniProtKB:Q05923] synonym: "Dual specificity protein phosphatase PAC-1" EXACT [UniProtKB:Q05923] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q05923] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q05923] xref: EMBL:AAA50779.1 xref: EMBL:AAA86112.1 xref: EMBL:AAH07771.1 xref: UniProtKB:Q05923 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007474 ! DUSP2_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0001839 ! protein tyrosine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008037 ! mitogen-activated protein kinase binding relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity [Term] id: CCO:B0021671 name: HBEGF_HUMAN def: "Proheparin-binding EGF-like growth factor precursor" [UniProtKB:Q99075] xref: EMBL:AAA35956.1 xref: EMBL:AAC15470.1 xref: EMBL:AAH33097.1 xref: EMBL:AAN46738.1 xref: UniProtKB:Q99075 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007615 ! HBEGF_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001456 ! epidermal growth factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0003130 ! positive regulation of keratinocyte migration [Term] id: CCO:B0021690 name: RPB1_HUMAN def: "DNA-directed RNA polymerase II subunit RPB1" [UniProtKB:P24928] synonym: "DNA-directed RNA polymerase II subunit A" EXACT [UniProtKB:P24928] synonym: "DNA-directed RNA polymerase III largest subunit" EXACT [UniProtKB:P24928] synonym: "EC 2.7.7.6" EXACT [UniProtKB:P24928] synonym: "RNA polymerase II subunit B1" EXACT [UniProtKB:P24928] xref: EMBL:CAA45125.1 xref: EMBL:CAA52862.1 xref: UniProtKB:P24928 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011662 ! POLR2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0006700 ! cdk8-q9btt4 physical interaction relationship: participates_in CCO:I0006701 ! crsp7-cdk8-1 physical interaction relationship: participates_in CCO:I0015884 ! xab2-polr2a-1 physical interaction relationship: participates_in CCO:I0015885 ! polr2a-xab2-1 physical interaction relationship: participates_in CCO:I0018426 ! polr2a-ercc6-1 physical interaction relationship: participates_in CCO:I0018765 ! xab2-ercc6-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039631 ! RPB1_HUMAN-Phosphotyrosine145 relationship: transforms_into CCO:B0039632 ! RPB1_HUMAN-Phosphoserine772 relationship: transforms_into CCO:B0039633 ! RPB1_HUMAN-Phosphoserine777 relationship: transforms_into CCO:B0039634 ! RPB1_HUMAN-Phosphoserine1878 relationship: transforms_into CCO:B0039635 ! RPB1_HUMAN-Phosphoserine1896 relationship: transforms_into CCO:B0039636 ! RPB1_HUMAN-Phosphotyrosine1923 relationship: transforms_into CCO:B0039637 ! RPB1_HUMAN-Phosphoserine1927 relationship: transforms_into CCO:B0039638 ! RPB1_HUMAN-Phosphothreonine1933 relationship: transforms_into CCO:B0039639 ! RPB1_HUMAN-Phosphoserine1934 [Term] id: CCO:B0021692 name: WISP1_HUMAN def: "WNT1-inducible-signaling pathway protein 1 precursor" [UniProtKB:O95388] synonym: "WISP-1" EXACT [UniProtKB:O95388] synonym: "Wnt-1-induced secreted protein" EXACT [UniProtKB:O95388] xref: EMBL:AAC96321.1 xref: EMBL:AAH74840.1 xref: EMBL:AAH74841.1 xref: EMBL:BAB17849.1 xref: UniProtKB:O95388 xref: UniProtKB:Q9HCS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013647 ! WISP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0021695 name: Q6PEG3_HUMAN def: "WISP2 protein" [UniProtKB:Q6PEG3] synonym: "WNT1 inducible signaling pathway protein 2" EXACT [UniProtKB:Q6PEG3] xref: EMBL:AAH58074.1 xref: EMBL:CAH73886.1 xref: UniProtKB:Q6PEG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015083 ! WISP2_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0021696 name: CTGF_HUMAN def: "Connective tissue growth factor precursor" [UniProtKB:P29279] synonym: "Hypertrophic chondrocyte-specific protein 24" EXACT [UniProtKB:P29279] xref: EMBL:AAA75378.1 xref: EMBL:AAA91279.1 xref: EMBL:AAK60505.1 xref: EMBL:AAK60506.1 xref: EMBL:AAK60507.1 xref: EMBL:AAQ95223.1 xref: EMBL:AAS55639.1 xref: EMBL:AAV38597.1 xref: EMBL:AAV38598.1 xref: EMBL:CAA55544.1 xref: EMBL:CAA63267.1 xref: EMBL:CAC44023.1 xref: EMBL:CAG46559.1 xref: UniProtKB:P29279 xref: UniProtKB:Q6LCY0 xref: UniProtKB:Q96A79 xref: UniProtKB:Q96QX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014689 ! CTGF_human relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0021697 name: NOV_HUMAN def: "Protein NOV homolog precursor" [UniProtKB:P48745] synonym: "Nephroblastoma overexpressed gene protein homolog" EXACT [UniProtKB:P48745] synonym: "NovH" EXACT [UniProtKB:P48745] xref: EMBL:AAH15028.1 xref: EMBL:AAL92490.1 xref: EMBL:CAA55146.1 xref: EMBL:CAA65403.1 xref: UniProtKB:P48745 xref: UniProtKB:Q96BY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014855 ! NOV_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0021699 name: WISP2_HUMAN def: "WNT1-inducible-signaling pathway protein 2 precursor" [UniProtKB:O76076] synonym: "Connective tissue growth factor-like protein" EXACT [UniProtKB:O76076] synonym: "Connective tissue growth factor-related protein 58" EXACT [UniProtKB:O76076] synonym: "CTGF-L" EXACT [UniProtKB:O76076] synonym: "WISP-2" EXACT [UniProtKB:O76076] xref: EMBL:AAC26794.1 xref: EMBL:AAC70350.1 xref: EMBL:AAC96322.1 xref: EMBL:AAH17782.1 xref: EMBL:AAH64379.1 xref: EMBL:AAQ89274.1 xref: EMBL:CAB94788.1 xref: UniProtKB:O76076 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015083 ! WISP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0021706 name: CITE1_HUMAN def: "Cbp/p300-interacting transactivator 1" [UniProtKB:Q99966] synonym: "Melanocyte-specific protein 1" EXACT [UniProtKB:Q99966] xref: EMBL:AAC51113.1 xref: EMBL:AAH04240.1 xref: UniProtKB:Q99966 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007393 ! CITED1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0021707 name: CITE4_HUMAN def: "Cbp/p300-interacting transactivator 4" [UniProtKB:Q96RK1] synonym: "MRG-2" EXACT [UniProtKB:Q96RK1] synonym: "MSG1-related protein 2" EXACT [UniProtKB:Q96RK1] xref: EMBL:AAH35496.1 xref: EMBL:AAH52559.1 xref: EMBL:AAK64235.1 xref: EMBL:AAL73989.1 xref: UniProtKB:Q96RK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007394 ! CITED4_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0021709 name: RPAC2_HUMAN def: "DNA-directed RNA polymerases I and III subunit RPAC2" [UniProtKB:Q9Y2S0] synonym: "AC19" EXACT [UniProtKB:Q9Y2S0] synonym: "DNA-directed RNA polymerase I 16 kDa polypeptide" EXACT [UniProtKB:Q9Y2S0] synonym: "DNA-directed RNA polymerase I subunit D" EXACT [UniProtKB:Q9Y2S0] synonym: "hRPA19" EXACT [UniProtKB:Q9Y2S0] synonym: "RNA polymerases I and III subunit AC2" EXACT [UniProtKB:Q9Y2S0] synonym: "RPA16" EXACT [UniProtKB:Q9Y2S0] synonym: "RPC16" EXACT [UniProtKB:Q9Y2S0] xref: EMBL:AAD27777.1 xref: EMBL:AAH00889.1 xref: EMBL:AAH15319.1 xref: EMBL:AAH18528.1 xref: EMBL:BAG34775.1 xref: EMBL:CAI16933.1 xref: EMBL:CAI16934.1 xref: EMBL:EAX08416.1 xref: UniProtKB:Q5TBX2 xref: UniProtKB:Q96BR3 xref: UniProtKB:Q9Y2S0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008121 ! POLR1D_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0017180 ! nfkbib-polr1d physical interaction [Term] id: CCO:B0021714 name: N62CL_HUMAN def: "Nucleoporin-62 C-terminal-like protein" [UniProtKB:Q9H1M0] xref: EMBL:AAH16327.1 xref: EMBL:AAH17799.1 xref: EMBL:BAA90968.1 xref: EMBL:CAC19637.1 xref: UniProtKB:Q8WVL6 xref: UniProtKB:Q9H1M0 xref: UniProtKB:Q9NXP2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007863 ! NUP62CL_human relationship: has_function CCO:F0003535 ! structural constituent of nuclear pore relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000260 ! nuclear pore relationship: participates_in CCO:I0015796 ! ogt-rp13_383k5_2 physical interaction [Term] id: CCO:B0021718 name: NUP62_HUMAN def: "Nuclear pore glycoprotein p62" [UniProtKB:P37198] synonym: "62 kDa nucleoporin" EXACT [UniProtKB:P37198] xref: EMBL:AAH03663.1 xref: EMBL:AAH14842.1 xref: EMBL:AAH50717.1 xref: EMBL:AAH95410.1 xref: EMBL:AAI01105.1 xref: EMBL:AAI01106.1 xref: EMBL:AAI01107.1 xref: EMBL:AAI01108.1 xref: EMBL:CAA41411.1 xref: EMBL:CAB82399.1 xref: EMBL:CAG46522.1 xref: EMBL:EAW52576.1 xref: UniProtKB:P37198 xref: UniProtKB:Q503A4 xref: UniProtKB:Q6GTM2 xref: UniProtKB:Q96C43 xref: UniProtKB:Q9NSL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007907 ! NUP62_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001632 ! nucleocytoplasmic transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003535 ! structural constituent of nuclear pore relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_function CCO:F0008108 ! PTB domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001119 ! nucleocytoplasmic shuttling complex relationship: located_in CCO:C0001978 ! pore complex relationship: participates_in CCO:I0014994 ! nup54-nup62 physical interaction relationship: participates_in CCO:I0015022 ! dtnb-nup62 physical interaction relationship: participates_in CCO:I0015655 ! nup62-thap1 physical interaction relationship: participates_in CCO:I0015745 ! gorasp2-nup62 physical interaction relationship: participates_in CCO:I0018442 ! pbx2-nup62 physical interaction relationship: participates_in CCO:I0020390 ! nup62-ik physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: participates_in CCO:P0002034 ! negative regulation of epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002154 ! negative regulation of non-apoptotic programmed cell death relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002530 ! positive regulation of epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002698 ! regulation of Ras protein signal transduction relationship: participates_in CCO:P0002700 ! negative regulation of Ras protein signal transduction [Term] id: CCO:B0021721 name: CTBP1_HUMAN def: "C-terminal-binding protein 1" [UniProtKB:Q13363] synonym: "CtBP1" EXACT [UniProtKB:Q13363] synonym: "EC 1.1.1.-" EXACT [UniProtKB:Q13363] xref: EMBL:AAC62822.1 xref: EMBL:AAD14597.1 xref: EMBL:AAH11655.1 xref: UniProtKB:Q13363 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017487 ! CTBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0064567 ! CTBP1_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0064568 ! CTBP1_HUMAN-Phosphoserine422 [Term] id: CCO:B0021723 name: CTBP2_HUMAN def: "C-terminal-binding protein 2" [UniProtKB:P56545] synonym: "CtBP2" EXACT [UniProtKB:P56545] xref: EMBL:AAC39603.1 xref: EMBL:AAG45951.1 xref: EMBL:AAH02486.1 xref: EMBL:AAH47018.1 xref: EMBL:AAH52276.1 xref: EMBL:AAH72020.1 xref: EMBL:AAP35658.1 xref: EMBL:CAH10590.1 xref: EMBL:CAH72472.1 xref: EMBL:CAI16100.1 xref: EMBL:CAI16102.1 xref: EMBL:EAW49247.1 xref: EMBL:EAW49250.1 xref: UniProtKB:O43449 xref: UniProtKB:P56545 xref: UniProtKB:Q5SQP7 xref: UniProtKB:Q69YI3 xref: UniProtKB:Q86SV0 xref: UniProtKB:Q9H2T8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017488 ! CTBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015007 ! baz2b-ctbp2 physical interaction relationship: participates_in CCO:I0015235 ! ctbp2-rai2 physical interaction relationship: participates_in CCO:I0015276 ! ctbp2-tead3 physical interaction relationship: participates_in CCO:I0015354 ! ctbp2-nol4 physical interaction relationship: participates_in CCO:I0015376 ! ctbp2-fts physical interaction relationship: participates_in CCO:I0015506 ! ctbp2-tgif physical interaction relationship: participates_in CCO:I0015610 ! ctbp2-nrip1 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0064569 ! CTBP2_HUMAN-Phosphoserine428 [Term] id: CCO:B0021755 name: A0N2G3_HUMAN def: "C-myc protein" [UniProtKB:A0N2G3] xref: EMBL:AAA59884.1 xref: UniProtKB:A0N2G3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005142 ! MYC_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021778 name: RNH2A_HUMAN def: "Ribonuclease H2 subunit A" [UniProtKB:O75792] synonym: "AGS4" EXACT [UniProtKB:O75792] synonym: "Aicardi-Goutieres syndrome 4 protein" EXACT [UniProtKB:O75792] synonym: "EC 3.1.26.4" EXACT [UniProtKB:O75792] synonym: "Ribonuclease HI large subunit" EXACT [UniProtKB:O75792] synonym: "Ribonuclease HI subunit A" EXACT [UniProtKB:O75792] synonym: "RNase H(35)" EXACT [UniProtKB:O75792] synonym: "RNase H2 subunit A" EXACT [UniProtKB:O75792] synonym: "RNase HI large subunit" EXACT [UniProtKB:O75792] xref: EMBL:AAH11748.1 xref: EMBL:CAB09725.1 xref: UniProtKB:O75792 xref: UniProtKB:Q96F11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019760 ! RNASEH2A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0000934 ! ribonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0021811 name: SYWC_HUMAN def: "Tryptophanyl-tRNA synthetase, cytoplasmic" [UniProtKB:P23381] synonym: "EC 6.1.1.2" EXACT [UniProtKB:P23381] synonym: "hWRS" EXACT [UniProtKB:P23381] synonym: "IFP53" EXACT [UniProtKB:P23381] synonym: "Interferon-induced protein 53" EXACT [UniProtKB:P23381] synonym: "TrpRS" EXACT [UniProtKB:P23381] synonym: "Tryptophan--tRNA ligase" EXACT [UniProtKB:P23381] xref: EMBL:AAA61298.1 xref: EMBL:AAA67324.1 xref: EMBL:AAB39381.1 xref: EMBL:AAH17489.1 xref: EMBL:CAA42545.1 xref: EMBL:CAA44450.1 xref: EMBL:CAB94198.1 xref: EMBL:CAB94199.1 xref: UniProtKB:P23381 xref: UniProtKB:P78535 xref: UniProtKB:Q9UDL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008257 ! WARS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001188 ! tryptophan-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020366 ! mdh2-wars physical interaction relationship: participates_in CCO:I0020544 ! doc_1r-wars physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0035722 ! SYWC_HUMAN-Phosphoserine467 [Term] id: CCO:B0021834 name: MOAP1_HUMAN def: "Modulator of apoptosis 1" [UniProtKB:Q96BY2] synonym: "MAP-1" EXACT [UniProtKB:Q96BY2] synonym: "MAP1" EXACT [UniProtKB:Q96BY2] synonym: "Paraneoplastic antigen Ma4" EXACT [UniProtKB:Q96BY2] xref: EMBL:AAG31786.1 xref: EMBL:AAH15044.1 xref: EMBL:BAB14788.1 xref: UniProtKB:Q96BY2 xref: UniProtKB:Q9H833 xref: UniProtKB:Q9HAS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013104 ! MOAP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0014953 ! mageh1-moap1 physical interaction relationship: participates_in CCO:I0018892 ! ubqln4-moap1 physical interaction relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000674 ! cell structure disassembly during apoptosis relationship: participates_in CCO:P0001250 ! apoptotic nuclear changes [Term] id: CCO:B0021842 name: VATE1_HUMAN def: "V-type proton ATPase subunit E 1" [UniProtKB:P36543] synonym: "P31" EXACT [UniProtKB:P36543] synonym: "V-ATPase 31 kDa subunit" EXACT [UniProtKB:P36543] synonym: "V-ATPase subunit E 1" EXACT [UniProtKB:P36543] synonym: "Vacuolar proton pump subunit E 1" EXACT [UniProtKB:P36543] xref: EMBL:AAH04443.1 xref: EMBL:CAA50592.1 xref: EMBL:CAA53814.1 xref: EMBL:CAG30271.1 xref: UniProtKB:P36543 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022774 ! ATP6V1E1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: participates_in CCO:I0019665 ! atp6v1e1-g22p1 physical interaction relationship: transforms_into CCO:B0071786 ! VATE1_HUMAN-Phosphotyrosine56 [Term] id: CCO:B0021859 name: IKZF2_HUMAN def: "Zinc finger protein Helios" [UniProtKB:Q9UKS7] synonym: "Ikaros family zinc finger protein 2" EXACT [UniProtKB:Q9UKS7] xref: EMBL:AAF09441.1 xref: EMBL:AAH28936.1 xref: UniProtKB:Q8N6S1 xref: UniProtKB:Q9UKS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011486 ! IKZF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039470 ! IKZF2_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0039471 ! IKZF2_HUMAN-Phosphotyrosine175 [Term] id: CCO:B0021866 name: IKZF4_HUMAN def: "Zinc finger protein Eos" [UniProtKB:Q9H2S9] synonym: "Ikaros family zinc finger protein 4" EXACT [UniProtKB:Q9H2S9] xref: EMBL:AAG39221.1 xref: EMBL:BAB47411.1 xref: UniProtKB:Q96JP3 xref: UniProtKB:Q9H2S9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011487 ! IKZF4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0021887 name: I17RB_HUMAN def: "Interleukin-17 receptor B precursor" [UniProtKB:Q9NRM6] synonym: "Cytokine receptor CRL4" EXACT [UniProtKB:Q9NRM6] synonym: "IL-17 receptor B" EXACT [UniProtKB:Q9NRM6] synonym: "IL-17 receptor homolog 1" EXACT [UniProtKB:Q9NRM6] synonym: "IL-17B receptor" EXACT [UniProtKB:Q9NRM6] synonym: "IL-17RB" EXACT [UniProtKB:Q9NRM6] synonym: "IL-17Rh1" EXACT [UniProtKB:Q9NRM6] synonym: "IL17Rh1" EXACT [UniProtKB:Q9NRM6] synonym: "Interleukin-17B receptor" EXACT [UniProtKB:Q9NRM6] xref: EMBL:AAF78776.1 xref: EMBL:AAF86051.1 xref: EMBL:AAF86052.1 xref: EMBL:AAH00980.1 xref: EMBL:AAK37428.1 xref: EMBL:AAQ89956.1 xref: EMBL:AAR89910.1 xref: UniProtKB:Q9BPZ0 xref: UniProtKB:Q9NRL4 xref: UniProtKB:Q9NRM5 xref: UniProtKB:Q9NRM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007639 ! IL17RB_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001254 ! interleukin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0021914 name: H2A2A_HUMAN def: "Histone H2A type 2-A" [UniProtKB:Q6FI13] synonym: "H2A.2" EXACT [UniProtKB:Q6FI13] synonym: "H2A/o" EXACT [UniProtKB:Q6FI13] xref: EMBL:AAC24465.1 xref: EMBL:AAH01629.1 xref: EMBL:AAH19308.1 xref: EMBL:AAH96705.1 xref: EMBL:AAH96739.1 xref: EMBL:AAH98171.1 xref: EMBL:AAN59957.1 xref: EMBL:CAG38762.1 xref: EMBL:CAG46670.1 xref: EMBL:CAI12562.1 xref: EMBL:CAI12565.1 xref: UniProtKB:P20670 xref: UniProtKB:Q6FI13 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022295 ! HIST2H2AA3_human relationship: encoded_by CCO:G0022296 ! HIST2H2AA4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0066688 ! H2A2A_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066689 ! H2A2A_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0066690 ! H2A2A_HUMAN-Citrulline4 relationship: transforms_into CCO:B0066691 ! H2A2A_HUMAN-dimethylarginine4 relationship: transforms_into CCO:B0066692 ! H2A2A_HUMAN-N6-acetyllysine6 relationship: transforms_into CCO:B0066693 ! H2A2A_HUMAN-Phosphothreonine121 [Term] id: CCO:B0021917 name: H2A1C_HUMAN def: "Histone H2A type 1-C" [UniProtKB:Q93077] synonym: "H2A/l" EXACT [UniProtKB:Q93077] xref: EMBL:AAB53429.1 xref: EMBL:AAB82086.1 xref: EMBL:AAH17379.1 xref: EMBL:AAH50602.1 xref: EMBL:AAH85010.1 xref: EMBL:AAN59965.1 xref: EMBL:CAB02540.1 xref: UniProtKB:O00775 xref: UniProtKB:O00776 xref: UniProtKB:O00777 xref: UniProtKB:O00778 xref: UniProtKB:Q540R1 xref: UniProtKB:Q93077 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022294 ! HIST1H2AC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020571 ! hist1h2ac-tfap2b physical interaction relationship: transforms_into CCO:B0066682 ! H2A1C_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066683 ! H2A1C_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0066684 ! H2A1C_HUMAN-Citrulline4 relationship: transforms_into CCO:B0066685 ! H2A1C_HUMAN-dimethylarginine4 relationship: transforms_into CCO:B0066686 ! H2A1C_HUMAN-N6-acetyllysine6 relationship: transforms_into CCO:B0066687 ! H2A1C_HUMAN-Phosphothreonine121 [Term] id: CCO:B0022038 name: ZHX2_HUMAN def: "Zinc fingers and homeoboxes protein 2" [UniProtKB:Q9Y6X8] synonym: "AFP regulator 1" EXACT [UniProtKB:Q9Y6X8] synonym: "Alpha-fetoprotein regulator 1" EXACT [UniProtKB:Q9Y6X8] synonym: "Regulator of AFP" EXACT [UniProtKB:Q9Y6X8] synonym: "Zinc finger and homeodomain protein 2" EXACT [UniProtKB:Q9Y6X8] xref: EMBL:AAH42145.1 xref: EMBL:BAA74877.2 xref: EMBL:BAC76615.1 xref: UniProtKB:Q9Y6X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020602 ! ZHX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019015 ! atxn1-zhx2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072034 ! ZHX2_HUMAN-Phosphoserine16 [Term] id: CCO:B0022040 name: ZHX3_HUMAN def: "Zinc fingers and homeoboxes protein 3" [UniProtKB:Q9H4I2] synonym: "Triple homeobox protein 1" EXACT [UniProtKB:Q9H4I2] synonym: "Zinc finger and homeodomain protein 3" EXACT [UniProtKB:Q9H4I2] xref: EMBL:BAA23691.3 xref: EMBL:BAC65211.1 xref: EMBL:CAA18538.1 xref: UniProtKB:O43145 xref: UniProtKB:Q9H4I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020603 ! ZHX3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019016 ! atxn1-zhx3 physical interaction relationship: participates_in CCO:I0019070 ! atxn1-zhx3-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072035 ! ZHX3_HUMAN-Phosphoserine680 relationship: transforms_into CCO:B0072036 ! ZHX3_HUMAN-Phosphoserine723 relationship: transforms_into CCO:B0072037 ! ZHX3_HUMAN-Phosphoserine946 [Term] id: CCO:B0022042 name: Q6NUJ7_HUMAN def: "ZHX3 protein" [UniProtKB:Q6NUJ7] xref: EMBL:AAH68569.1 xref: UniProtKB:Q6NUJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020603 ! ZHX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0022045 name: Q5JZ70_HUMAN def: "Zinc fingers and homeoboxes 3" [UniProtKB:Q5JZ70] xref: EMBL:CAI42887.1 xref: UniProtKB:Q5JZ70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020603 ! ZHX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0022046 name: Q5JZ69_HUMAN def: "Zinc fingers and homeoboxes 3" [UniProtKB:Q5JZ69] xref: EMBL:CAI42888.1 xref: UniProtKB:Q5JZ69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020603 ! ZHX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0022069 name: Q5VZI8_HUMAN xref: UniProtKB:Q5VZI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022071 name: TLR4_HUMAN def: "Toll-like receptor 4 precursor" [UniProtKB:O00206] synonym: "CD284 antigen" EXACT [UniProtKB:O00206] synonym: "hToll" EXACT [UniProtKB:O00206] xref: EMBL:AAC34135.1 xref: EMBL:AAC80227.1 xref: EMBL:AAF05316.1 xref: EMBL:AAF07823.1 xref: EMBL:AAF89753.1 xref: EMBL:AAI17423.1 xref: EMBL:ABU41662.1 xref: EMBL:ABU41663.1 xref: EMBL:ABU41664.1 xref: EMBL:BAF82742.1 xref: EMBL:BAF85757.1 xref: EMBL:BAG55035.1 xref: EMBL:BAG64706.1 xref: EMBL:CAH72618.1 xref: EMBL:CAH72619.1 xref: EMBL:EAW87448.1 xref: EMBL:EAW87451.1 xref: UniProtKB:A8K1Y8 xref: UniProtKB:A9XLP9 xref: UniProtKB:A9XLQ0 xref: UniProtKB:A9XLQ1 xref: UniProtKB:B4E194 xref: UniProtKB:O00206 xref: UniProtKB:Q5VZI8 xref: UniProtKB:Q5VZI9 xref: UniProtKB:Q9UK78 xref: UniProtKB:Q9UM57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020280 ! TLR4_human relationship: has_function CCO:F0000132 ! lipopolysaccharide binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: located_in CCO:C0001962 ! lipopolysaccharide receptor complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0016269 ! tirap-tlr4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002099 ! positive regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002276 ! positive regulation of interleukin-12 biosynthetic process relationship: participates_in CCO:P0002357 ! positive regulation of interleukin-8 biosynthetic process relationship: participates_in CCO:P0002485 ! negative regulation of osteoclast differentiation [Term] id: CCO:B0022073 name: SMC6_HUMAN def: "Structural maintenance of chromosomes protein 6" [UniProtKB:Q96SB8] synonym: "hSMC6" EXACT [UniProtKB:Q96SB8] xref: EMBL:AAH32675.1 xref: EMBL:AAH39828.1 xref: EMBL:AAX88851.1 xref: EMBL:BAB15236.1 xref: EMBL:CAB66479.1 xref: EMBL:CAC39248.1 xref: EMBL:CAH56327.1 xref: UniProtKB:Q05BV4 xref: UniProtKB:Q96SB8 xref: UniProtKB:Q9H0X3 xref: UniProtKB:Q9H6M0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011682 ! SMC6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction [Term] id: CCO:B0022139 name: DYN1_HUMAN def: "Dynamin-1" [UniProtKB:Q05193] synonym: "EC 3.6.5.5" EXACT [UniProtKB:Q05193] xref: EMBL:AAA02803.1 xref: EMBL:AAA02804.1 xref: EMBL:AAA02805.1 xref: EMBL:AAA02806.1 xref: EMBL:AAH50279.2 xref: EMBL:AAH63850.1 xref: EMBL:CAI13837.1 xref: EMBL:CAI13839.2 xref: UniProtKB:A6NLM6 xref: UniProtKB:Q05193 xref: UniProtKB:Q5SYX0 xref: UniProtKB:Q5SYX2 xref: UniProtKB:Q6P3T6 xref: UniProtKB:Q86VD2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007475 ! DNM1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0017396 ! nck-dnm1-2 physical interaction relationship: participates_in CCO:I0017397 ! grb2-dnm1-4 physical interaction relationship: participates_in CCO:I0017911 ! nck-dnm1-3 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:I0019974 ! dnm1-med31 physical interaction relationship: participates_in CCO:I0020294 ! dnm1-asb13 physical interaction relationship: transforms_into CCO:B0034720 ! DYN1_HUMAN-Phosphotyrosine80 relationship: transforms_into CCO:B0034721 ! DYN1_HUMAN-Phosphotyrosine125 relationship: transforms_into CCO:B0034722 ! DYN1_HUMAN-Phosphotyrosine354 relationship: transforms_into CCO:B0043253 ! DYN1_HUMAN-Nitrated tyrosine125 relationship: transforms_into CCO:B0043254 ! DYN1_HUMAN-Phosphoserine774 relationship: transforms_into CCO:B0043255 ! DYN1_HUMAN-Phosphothreonine776 relationship: transforms_into CCO:B0043256 ! DYN1_HUMAN-Phosphoserine778 [Term] id: CCO:B0022152 name: Q4LE71_HUMAN def: "SLC9A3R2 variant protein" [UniProtKB:Q4LE71] xref: EMBL:BAE06082.1 xref: UniProtKB:Q4LE71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008576 ! SLC9A3R2 variant protein_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0022200 name: CSN4_HUMAN def: "COP9 signalosome complex subunit 4" [UniProtKB:Q9BT78] synonym: "JAB1-containing signalosome subunit 4" EXACT [UniProtKB:Q9BT78] synonym: "SGN4" EXACT [UniProtKB:Q9BT78] synonym: "Signalosome subunit 4" EXACT [UniProtKB:Q9BT78] xref: EMBL:AAD43021.1 xref: EMBL:AAH04302.1 xref: EMBL:AAH09292.1 xref: EMBL:AAH93007.1 xref: EMBL:BAA91555.1 xref: UniProtKB:Q561W7 xref: UniProtKB:Q9BT78 xref: UniProtKB:Q9NW31 xref: UniProtKB:Q9Y677 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022156 ! COPS4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000530 ! signalosome relationship: participates_in CCO:I0015591 ! cops4-mbip physical interaction [Term] id: CCO:B0022204 name: PSA5_HUMAN def: "Proteasome subunit alpha type-5" [UniProtKB:P28066] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P28066] synonym: "Macropain zeta chain" EXACT [UniProtKB:P28066] synonym: "Multicatalytic endopeptidase complex zeta chain" EXACT [UniProtKB:P28066] synonym: "Proteasome zeta chain" EXACT [UniProtKB:P28066] xref: EMBL:AAI02019.1 xref: EMBL:AAI02020.1 xref: EMBL:AAI02021.1 xref: EMBL:AAI03752.1 xref: EMBL:CAA43962.1 xref: EMBL:CAG33128.1 xref: EMBL:CAH70887.1 xref: EMBL:CAI13171.1 xref: UniProtKB:P28066 xref: UniProtKB:Q3T1C1 xref: UniProtKB:Q6IBF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008017 ! PSMA5_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008703 ! nfkbie-psma5 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035474 ! PSA5_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0035475 ! PSA5_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0035476 ! PSA5_HUMAN-Phosphoserine56 [Term] id: CCO:B0022223 name: ID1_HUMAN def: "DNA-binding protein inhibitor ID-1" [UniProtKB:P41134] synonym: "Inhibitor of DNA binding 1" EXACT [UniProtKB:P41134] xref: EMBL:AAB35037.1 xref: EMBL:AAB35038.1 xref: EMBL:AAC13882.1 xref: EMBL:AAC13883.1 xref: EMBL:AAH00613.1 xref: EMBL:AAH12420.1 xref: EMBL:AAP36111.1 xref: EMBL:BAA02988.1 xref: EMBL:BAA02989.1 xref: EMBL:CAA54920.1 xref: EMBL:CAC14950.2 xref: EMBL:CAI20171.1 xref: EMBL:CAI23029.1 xref: EMBL:CAI23030.1 xref: UniProtKB:O00651 xref: UniProtKB:O00652 xref: UniProtKB:P41134 xref: UniProtKB:Q16371 xref: UniProtKB:Q16377 xref: UniProtKB:Q5TE66 xref: UniProtKB:Q5TE67 xref: UniProtKB:Q969Z7 xref: UniProtKB:Q9H0Z5 xref: UniProtKB:Q9H109 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018216 ! ID1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0022226 name: ID4_HUMAN def: "DNA-binding protein inhibitor ID-4" [UniProtKB:P47928] synonym: "Inhibitor of DNA binding 4" EXACT [UniProtKB:P47928] xref: EMBL:AAA73923.1 xref: EMBL:AAA82882.1 xref: EMBL:AAH14941.1 xref: EMBL:CAA18779.1 xref: EMBL:CAA69255.1 xref: UniProtKB:P47928 xref: UniProtKB:Q13005 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018217 ! ID4_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation relationship: participates_in CCO:P0002884 ! negative regulation of astrocyte differentiation [Term] id: CCO:B0022232 name: PPID_HUMAN def: "40 kDa peptidyl-prolyl cis-trans isomerase" [UniProtKB:Q08752] synonym: "Cyclophilin-40" EXACT [UniProtKB:Q08752] synonym: "Cyclophilin-related protein" EXACT [UniProtKB:Q08752] synonym: "CYP-40" EXACT [UniProtKB:Q08752] synonym: "EC 5.2.1.8" EXACT [UniProtKB:Q08752] synonym: "PPIase" EXACT [UniProtKB:Q08752] synonym: "Rotamase" EXACT [UniProtKB:Q08752] xref: EMBL:AAA35731.1 xref: EMBL:AAH30707.1 xref: EMBL:AAT97986.1 xref: EMBL:BAA09923.1 xref: UniProtKB:Q08752 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008003 ! PPID_human relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003031 ! cyclosporin A binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0005639 ! peptide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:I0020118 ! ppid-myst2 physical interaction [Term] id: CCO:B0022236 name: PPAC_HUMAN def: "Low molecular weight phosphotyrosine protein phosphatase" [UniProtKB:P24666] synonym: "Adipocyte acid phosphatase" EXACT [UniProtKB:P24666] synonym: "EC 3.1.3.2" EXACT [UniProtKB:P24666] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P24666] synonym: "LMW-PTP" EXACT [UniProtKB:P24666] synonym: "LMW-PTPase" EXACT [UniProtKB:P24666] synonym: "Low molecular weight cytosolic acid phosphatase" EXACT [UniProtKB:P24666] synonym: "Red cell acid phosphatase 1" EXACT [UniProtKB:P24666] xref: EMBL:AAB27085.1 xref: EMBL:AAB27086.1 xref: EMBL:AAB59354.1 xref: EMBL:AAB59355.1 xref: EMBL:AAB59628.1 xref: EMBL:AAC52067.1 xref: EMBL:AAH07422.1 xref: EMBL:AAP35800.1 xref: EMBL:AAY14958.1 xref: EMBL:BAF84550.1 xref: EMBL:EAX01112.1 xref: UniProtKB:P24666 xref: UniProtKB:P24667 xref: UniProtKB:Q16035 xref: UniProtKB:Q16036 xref: UniProtKB:Q16725 xref: UniProtKB:Q53RU0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007996 ! ACP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015778 ! acp1-sfmbt1 physical interaction relationship: transforms_into CCO:B0035416 ! PPAC_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035417 ! PPAC_HUMAN-Phosphotyrosine132 relationship: transforms_into CCO:B0035418 ! PPAC_HUMAN-Phosphotyrosine133 [Term] id: CCO:B0022296 name: Q3LRW1_HUMAN def: "Cellular tumor antigen p53" [UniProtKB:Q3LRW1] xref: EMBL:ABA29757.1 xref: UniProtKB:Q3LRW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005245 ! TP53_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0022298 name: Q3LRW4_HUMAN def: "Cellular tumor antigen p53" [UniProtKB:Q3LRW4] xref: EMBL:ABA29754.1 xref: UniProtKB:Q3LRW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005245 ! TP53_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0022300 name: P63_HUMAN def: "Tumor protein 63" [UniProtKB:Q9H3D4] synonym: "Chronic ulcerative stomatitis protein" EXACT [UniProtKB:Q9H3D4] synonym: "CUSP" EXACT [UniProtKB:Q9H3D4] synonym: "Keratinocyte transcription factor KET" EXACT [UniProtKB:Q9H3D4] synonym: "p40" EXACT [UniProtKB:Q9H3D4] synonym: "p51" EXACT [UniProtKB:Q9H3D4] synonym: "p63" EXACT [UniProtKB:Q9H3D4] synonym: "p73L" EXACT [UniProtKB:Q9H3D4] synonym: "TP63" EXACT [UniProtKB:Q9H3D4] synonym: "Transformation-related protein 63" EXACT [UniProtKB:Q9H3D4] synonym: "Tumor protein p73-like" EXACT [UniProtKB:Q9H3D4] xref: EMBL:AAC24830.1 xref: EMBL:AAC43038.1 xref: EMBL:AAC62633.1 xref: EMBL:AAC62634.1 xref: EMBL:AAC62635.1 xref: EMBL:AAC62636.1 xref: EMBL:AAC62637.1 xref: EMBL:AAC62638.1 xref: EMBL:AAF43486.1 xref: EMBL:AAF43487.1 xref: EMBL:AAF43488.1 xref: EMBL:AAF43489.1 xref: EMBL:AAF43490.1 xref: EMBL:AAF43491.1 xref: EMBL:AAF43492.1 xref: EMBL:AAF43493.1 xref: EMBL:AAF61624.1 xref: EMBL:AAG45607.1 xref: EMBL:AAG45608.1 xref: EMBL:AAG45609.1 xref: EMBL:AAG45610.1 xref: EMBL:AAG45611.1 xref: EMBL:AAG45612.1 xref: EMBL:AAH39815.1 xref: EMBL:AAQ63448.1 xref: EMBL:AAQ63449.1 xref: EMBL:AAQ63450.1 xref: EMBL:AAQ63451.1 xref: EMBL:AAQ63452.1 xref: EMBL:AAQ63453.1 xref: EMBL:AAQ63454.1 xref: EMBL:BAA32433.1 xref: EMBL:BAA32592.1 xref: EMBL:BAA32593.1 xref: EMBL:BAB20591.1 xref: EMBL:CAA76562.1 xref: EMBL:CAC48053.1 xref: UniProtKB:O75080 xref: UniProtKB:O75195 xref: UniProtKB:O75922 xref: UniProtKB:O76078 xref: UniProtKB:Q6VEG2 xref: UniProtKB:Q6VEG3 xref: UniProtKB:Q6VEG4 xref: UniProtKB:Q6VFJ1 xref: UniProtKB:Q6VFJ2 xref: UniProtKB:Q6VFJ3 xref: UniProtKB:Q6VH20 xref: UniProtKB:Q7LDI3 xref: UniProtKB:Q7LDI4 xref: UniProtKB:Q7LDI5 xref: UniProtKB:Q96KR0 xref: UniProtKB:Q9H3D2 xref: UniProtKB:Q9H3D3 xref: UniProtKB:Q9H3D4 xref: UniProtKB:Q9H3P8 xref: UniProtKB:Q9NPH7 xref: UniProtKB:Q9P1B4 xref: UniProtKB:Q9P1B5 xref: UniProtKB:Q9P1B6 xref: UniProtKB:Q9P1B7 xref: UniProtKB:Q9UBV9 xref: UniProtKB:Q9UE10 xref: UniProtKB:Q9UP26 xref: UniProtKB:Q9UP27 xref: UniProtKB:Q9UP28 xref: UniProtKB:Q9UP74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007945 ! TP63_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002535 ! positive regulation of Notch signaling pathway relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0022308 name: Q1MSW9_HUMAN def: "Cellular tumor antigen p53" [UniProtKB:Q1MSW9] xref: EMBL:ABL09848.1 xref: EMBL:CAJ28924.1 xref: UniProtKB:Q1MSW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005245 ! TP53_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0022312 name: Q3LRW3_HUMAN def: "Cellular tumor antigen p53" [UniProtKB:Q3LRW3] xref: EMBL:ABA29755.1 xref: UniProtKB:Q3LRW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005245 ! TP53_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0022381 name: ZN667_HUMAN def: "Zinc finger protein 667" [UniProtKB:Q5HYK9] xref: EMBL:AAH74898.2 xref: EMBL:AAH74899.2 xref: EMBL:BAB14816.1 xref: EMBL:CAI46040.1 xref: UniProtKB:Q5HYK9 xref: UniProtKB:Q6B093 xref: UniProtKB:Q9H807 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008371 ! ZNF667_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0022382 name: Q9ULA1_HUMAN def: "R31155_1 (Zinc finger protein 667, isoform CRA_a)" [UniProtKB:Q9ULA1] xref: EMBL:AAF06067.1 xref: EMBL:EAW72453.1 xref: UniProtKB:Q9ULA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008371 ! ZNF667_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0022431 name: OSGI1_HUMAN def: "Oxidative stress-induced growth inhibitor 1" [UniProtKB:Q9UJX0] synonym: "huOKL38" EXACT [UniProtKB:Q9UJX0] synonym: "Ovary, kidney and liver protein 38" EXACT [UniProtKB:Q9UJX0] synonym: "Pregnancy-induced growth inhibitor OKL38" EXACT [UniProtKB:Q9UJX0] xref: EMBL:AAF06662.1 xref: EMBL:AAH32476.1 xref: EMBL:AAK01722.2 xref: EMBL:AAK67637.1 xref: EMBL:AAP14662.1 xref: EMBL:AAP14663.1 xref: EMBL:AAP14664.1 xref: UniProtKB:Q86UQ1 xref: UniProtKB:Q96S88 xref: UniProtKB:Q9BZ70 xref: UniProtKB:Q9UJX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007937 ! OSGIN1_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0022444 name: TF2B_HUMAN def: "Transcription initiation factor IIB" [UniProtKB:Q00403] synonym: "General transcription factor TFIIB" EXACT [UniProtKB:Q00403] synonym: "S300-II" EXACT [UniProtKB:Q00403] xref: EMBL:AAA61149.1 xref: EMBL:AAB23144.1 xref: EMBL:AAH20597.1 xref: EMBL:AAH21000.1 xref: EMBL:CAA41958.1 xref: EMBL:CAI41341.1 xref: UniProtKB:Q00403 xref: UniProtKB:Q5JS30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020238 ! GTF2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018141 ! gtf2b-tbp-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071361 ! TF2B_HUMAN-Phosphoserine76 [Term] id: CCO:B0022449 name: A2I2N5_HUMAN def: "Period 3" [UniProtKB:A2I2N5] xref: EMBL:ABM64204.1 xref: UniProtKB:A2I2N5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019368 ! PER3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022450 name: Q5H8X5_HUMAN def: "Period homolog 3 (Drosophila)" [UniProtKB:Q5H8X5] xref: EMBL:CAI21435.1 xref: UniProtKB:Q5H8X5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019368 ! PER3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022451 name: Q8TAR6_HUMAN def: "PER3 protein" [UniProtKB:Q8TAR6] synonym: "Period homolog 3 (Drosophila)" EXACT [UniProtKB:Q8TAR6] xref: EMBL:AAH26102.1 xref: EMBL:CAI21434.1 xref: UniProtKB:Q8TAR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019368 ! PER3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022452 name: PER3_HUMAN def: "Period circadian protein homolog 3" [UniProtKB:P56645] synonym: "Cell growth-inhibiting gene 13 protein" EXACT [UniProtKB:P56645] synonym: "Circadian clock protein PERIOD 3" EXACT [UniProtKB:P56645] synonym: "hPER3" EXACT [UniProtKB:P56645] xref: EMBL:AAS72879.1 xref: EMBL:BAB32925.2 xref: EMBL:BAB63250.1 xref: EMBL:BAB63251.1 xref: EMBL:BAB63252.1 xref: EMBL:BAB63253.1 xref: EMBL:BAB63254.1 xref: EMBL:BAB63255.1 xref: EMBL:CAB76084.1 xref: EMBL:CAI21436.1 xref: UniProtKB:P56645 xref: UniProtKB:Q5H8X4 xref: UniProtKB:Q969K6 xref: UniProtKB:Q96S77 xref: UniProtKB:Q96S78 xref: UniProtKB:Q9C0J3 xref: UniProtKB:Q9NSP9 xref: UniProtKB:Q9UGU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019368 ! PER3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022454 name: KAP3_HUMAN def: "cAMP-dependent protein kinase type II-beta regulatory subunit" [UniProtKB:P31323] xref: EMBL:AAA60099.1 xref: EMBL:BAF84130.1 xref: EMBL:EAL24395.1 xref: EMBL:EAW83390.1 xref: UniProtKB:A4D0R9 xref: UniProtKB:P31323 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007719 ! PRKAR2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0034968 ! KAP3_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0034969 ! KAP3_HUMAN-Phosphoserine114 [Term] id: CCO:B0022455 name: KAP2_HUMAN def: "cAMP-dependent protein kinase type II-alpha regulatory subunit" [UniProtKB:P13861] xref: EMBL:CAA33094.1 xref: EMBL:CAA67817.1 xref: UniProtKB:P13861 xref: UniProtKB:Q16823 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007718 ! PRKAR2A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0004464 ! cAMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0034962 ! KAP2_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0034963 ! KAP2_HUMAN-Phosphothreonine54 relationship: transforms_into CCO:B0034964 ! KAP2_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0034965 ! KAP2_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0034966 ! KAP2_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0034967 ! KAP2_HUMAN-Phosphoserine99 [Term] id: CCO:B0022458 name: Q9BUB1_HUMAN def: "PRKAR2A protein" [UniProtKB:Q9BUB1] synonym: "Protein kinase, cAMP-dependent, regulatory, type II, alpha" EXACT [UniProtKB:Q9BUB1] synonym: "Protein kinase, cAMP-dependent, regulatory, type II, alpha, isoform CRA_b" EXACT [UniProtKB:Q9BUB1] xref: EMBL:AAH02763.1 xref: EMBL:AAP35889.1 xref: EMBL:EAW64926.1 xref: UniProtKB:Q9BUB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007718 ! PRKAR2A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022490 name: MAGG1_HUMAN def: "Melanoma-associated antigen G1" [UniProtKB:Q96MG7] synonym: "Hepatocellular carcinoma-associated protein 4" EXACT [UniProtKB:Q96MG7] synonym: "MAGE-G1 antigen" EXACT [UniProtKB:Q96MG7] synonym: "Necdin-like protein 2" EXACT [UniProtKB:Q96MG7] xref: EMBL:AAG38607.1 xref: EMBL:AAH41166.2 xref: EMBL:AAH53999.1 xref: EMBL:AAM08357.1 xref: EMBL:BAB71325.1 xref: EMBL:BAB84964.1 xref: UniProtKB:Q8IW16 xref: UniProtKB:Q8TEI6 xref: UniProtKB:Q96MG7 xref: UniProtKB:Q9H214 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018558 ! NDNL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067850 ! MAGG1_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0067851 ! MAGG1_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0067852 ! MAGG1_HUMAN-Phosphoserine64 [Term] id: CCO:B0022509 name: MAGC1_HUMAN def: "Melanoma-associated antigen C1" [UniProtKB:O60732] synonym: "Cancer/testis antigen 7.1" EXACT [UniProtKB:O60732] synonym: "CT7.1" EXACT [UniProtKB:O60732] synonym: "MAGE-C1 antigen" EXACT [UniProtKB:O60732] xref: EMBL:AAC18837.1 xref: EMBL:AAC24227.1 xref: EMBL:CAD27434.1 xref: UniProtKB:O60732 xref: UniProtKB:O75451 xref: UniProtKB:Q8TCV4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022386 ! MAGEC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018132 ! magec1-gtf2f1 physical interaction [Term] id: CCO:B0022559 name: SLAP2_HUMAN def: "Src-like-adapter 2" [UniProtKB:Q9H6Q3] synonym: "MARS" EXACT [UniProtKB:Q9H6Q3] synonym: "Modulator of antigen receptor signaling" EXACT [UniProtKB:Q9H6Q3] synonym: "SLAP-2" EXACT [UniProtKB:Q9H6Q3] synonym: "Src-like adapter protein 2" EXACT [UniProtKB:Q9H6Q3] xref: EMBL:AAH42041.1 xref: EMBL:AAL29204.1 xref: EMBL:AAL38197.1 xref: EMBL:AAL38198.1 xref: EMBL:BAB15201.1 xref: EMBL:CAI21397.1 xref: EMBL:CAI21398.1 xref: EMBL:CAI23504.1 xref: EMBL:CAI23505.1 xref: UniProtKB:Q5TH27 xref: UniProtKB:Q5TH28 xref: UniProtKB:Q8WY18 xref: UniProtKB:Q96QI4 xref: UniProtKB:Q9H135 xref: UniProtKB:Q9H6Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008186 ! SLA2_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001281 ! intracellular receptor-mediated signaling pathway relationship: participates_in CCO:P0002967 ! negative regulation of calcium-mediated signaling relationship: participates_in CCO:P0002969 ! antigen receptor-mediated signaling pathway relationship: participates_in CCO:P0002987 ! negative regulation of B cell activation [Term] id: CCO:B0022617 name: A6ZIS4_HUMAN def: "Extraembryonic spermatogenesis homeobox 1-like protein" [UniProtKB:A6ZIS4] xref: EMBL:ABS01454.1 xref: UniProtKB:A6ZIS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017732 ! ESX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0022629 name: A6ZIT3_HUMAN def: "Extraembryonic spermatogenesis homeobox 1-like protein" [UniProtKB:A6ZIT3] xref: EMBL:ABS01463.1 xref: UniProtKB:A6ZIT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017732 ! ESX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0022719 name: Q6IF88_HUMAN def: "Olfactory receptor OR3-11 (Olfactory receptor, family 5, subfamily H, member 6)" [UniProtKB:Q6IF88] xref: EMBL:AAI37524.1 xref: EMBL:AAI37525.1 xref: EMBL:DAA04772.1 xref: UniProtKB:Q6IF88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007923 ! OR5H6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022721 name: OR5K3_HUMAN def: "Olfactory receptor 5K3" [UniProtKB:A6NET4] xref: UniProtKB:A6NET4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007928 ! OR5K3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022723 name: OR5K1_HUMAN def: "Olfactory receptor 5K1" [UniProtKB:Q8NHB7] synonym: "HTPCRX10" EXACT [UniProtKB:Q8NHB7] synonym: "Olfactory receptor OR3-8" EXACT [UniProtKB:Q8NHB7] xref: EMBL:BAC05718.1 xref: EMBL:DAA04814.1 xref: UniProtKB:Q6IF46 xref: UniProtKB:Q8NHB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007926 ! OR5K1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022725 name: Q8NHB6_HUMAN def: "Olfactory receptor 5H14." [UniProtKB:Q8NHB6] xref: EMBL:BAC05719.1 xref: UniProtKB:Q8NHB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007911 ! OR5H14_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022726 name: O5AC2_HUMAN def: "Olfactory receptor 5AC2" [UniProtKB:Q9NZP5] synonym: "HSA1" EXACT [UniProtKB:Q9NZP5] xref: EMBL:AAF40348.1 xref: UniProtKB:Q9NZP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007909 ! OR5AC2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022728 name: OR5H1_HUMAN def: "Olfactory receptor 5H1" [UniProtKB:A6NKK0] synonym: "HTPCRX14" EXACT [UniProtKB:A6NKK0] xref: UniProtKB:A6NKK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007921 ! OR5H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022729 name: O5H15_HUMAN def: "Olfactory receptor 5H15" [UniProtKB:A6NDH6] xref: UniProtKB:A6NDH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007912 ! OR5H15_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022730 name: Q6IF87_HUMAN xref: UniProtKB:Q6IF87 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022731 name: OR5K2_HUMAN def: "Olfactory receptor 5K2" [UniProtKB:Q8NHB8] synonym: "Olfactory receptor OR3-9" EXACT [UniProtKB:Q8NHB8] xref: EMBL:BAC05717.1 xref: EMBL:DAA04813.1 xref: UniProtKB:Q6IF47 xref: UniProtKB:Q8NHB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007927 ! OR5K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022743 name: STK24_HUMAN def: "Serine/threonine-protein kinase 24" [UniProtKB:Q9Y6E0] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y6E0] synonym: "Mammalian STE20-like protein kinase 3" EXACT [UniProtKB:Q9Y6E0] synonym: "MST-3" EXACT [UniProtKB:Q9Y6E0] synonym: "STE20-like kinase MST3" EXACT [UniProtKB:Q9Y6E0] xref: EMBL:AAB82560.1 xref: EMBL:AAD42039.1 xref: EMBL:AAH35578.1 xref: UniProtKB:O14840 xref: UniProtKB:Q9Y6E0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008244 ! STK24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014960 ! pdcd10-stk24 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035700 ! STK24_HUMAN-Phosphothreonine18 relationship: transforms_into CCO:B0035701 ! STK24_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0035702 ! STK24_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0035703 ! STK24_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0035704 ! STK24_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0035705 ! STK24_HUMAN-Phosphoserine320 [Term] id: CCO:B0022748 name: STK25_HUMAN def: "Serine/threonine-protein kinase 25" [UniProtKB:O00506] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O00506] synonym: "SOK-1" EXACT [UniProtKB:O00506] synonym: "Ste20-like kinase" EXACT [UniProtKB:O00506] synonym: "Ste20/oxidant stress response kinase 1" EXACT [UniProtKB:O00506] synonym: "Sterile 20/oxidant stress-response kinase 1" EXACT [UniProtKB:O00506] xref: EMBL:AAH07852.1 xref: EMBL:AAH91505.1 xref: EMBL:AAV38764.1 xref: EMBL:AAY14683.1 xref: EMBL:AAY88740.1 xref: EMBL:BAA20420.1 xref: EMBL:CAA67700.1 xref: UniProtKB:O00506 xref: UniProtKB:Q15522 xref: UniProtKB:Q5BJF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008245 ! STK25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015528 ! pdcd10-stk25 physical interaction relationship: participates_in CCO:I0015943 ! stk25-golga2-3 physical interaction relationship: participates_in CCO:I0018315 ! stk25-golga2-2 physical interaction relationship: participates_in CCO:I0018643 ! stk25-ywhaz -2 phosphorylation relationship: participates_in CCO:I0019384 ! stk25-ywhaz -1 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035706 ! STK25_HUMAN-Phosphothreonine168 relationship: transforms_into CCO:B0035707 ! STK25_HUMAN-Phosphothreonine174 relationship: transforms_into CCO:B0035708 ! STK25_HUMAN-Phosphoserine342 [Term] id: CCO:B0022753 name: MST4_HUMAN def: "Serine/threonine-protein kinase MST4" [UniProtKB:Q9P289] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9P289] synonym: "Mammalian STE20-like protein kinase 4" EXACT [UniProtKB:Q9P289] synonym: "MST-4" EXACT [UniProtKB:Q9P289] synonym: "Mst3 and SOK1-related kinase" EXACT [UniProtKB:Q9P289] synonym: "Serine/threonine-protein kinase MASK" EXACT [UniProtKB:Q9P289] synonym: "STE20-like kinase MST4" EXACT [UniProtKB:Q9P289] xref: EMBL:AAH98315.1 xref: EMBL:AAI03504.1 xref: EMBL:AAK29620.1 xref: EMBL:AAK38484.1 xref: EMBL:AAV38902.1 xref: EMBL:BAA92785.2 xref: EMBL:CAI42079.1 xref: UniProtKB:Q3ZB77 xref: UniProtKB:Q9BXC4 xref: UniProtKB:Q9P289 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007839 ! MST4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:I0015944 ! mst4-golga2-1 physical interaction relationship: participates_in CCO:I0017740 ! mst4-mst4-1 physical interaction relationship: participates_in CCO:I0018646 ! mst4-mst4-4 phosphorylation relationship: participates_in CCO:I0018828 ! mst4-mst4-2 physical interaction relationship: participates_in CCO:I0018829 ! mst4-mst4-3 physical interaction relationship: participates_in CCO:I0018830 ! mst4-golga2-3 colocalization relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0035214 ! MST4_HUMAN-Phosphothreonine178 relationship: transforms_into CCO:B0068299 ! MST4_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0068300 ! MST4_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0068301 ! MST4_HUMAN-Phosphoserine306 [Term] id: CCO:B0022762 name: CASS4_HUMAN def: "Cas scaffolding protein family member 4" [UniProtKB:Q9NQ75] synonym: "HEF-like protein" EXACT [UniProtKB:Q9NQ75] synonym: "HEF1-EFS-p130Cas-like protein" EXACT [UniProtKB:Q9NQ75] synonym: "HEPL" EXACT [UniProtKB:Q9NQ75] xref: EMBL:AAH27951.1 xref: EMBL:BAB55351.1 xref: EMBL:CAC00655.1 xref: EMBL:CAC12719.2 xref: UniProtKB:Q96K09 xref: UniProtKB:Q9BYL5 xref: UniProtKB:Q9NQ75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022089 ! CASS4_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065822 ! CASS4_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0065823 ! CASS4_HUMAN-Phosphoserine249 relationship: transforms_into CCO:B0065824 ! CASS4_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0065825 ! CASS4_HUMAN-Phosphotyrosine329 relationship: transforms_into CCO:B0065826 ! CASS4_HUMAN-Phosphotyrosine350 relationship: transforms_into CCO:B0065827 ! CASS4_HUMAN-Phosphoserine390 [Term] id: CCO:B0022781 name: PIM1_HUMAN def: "Proto-oncogene serine/threonine-protein kinase Pim-1" [UniProtKB:P11309] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P11309] xref: EMBL:AAA36447.1 xref: EMBL:AAA60089.1 xref: EMBL:AAA60090.1 xref: EMBL:AAA81553.1 xref: EMBL:AAH20224.1 xref: EMBL:AAK70871.1 xref: EMBL:AAY87461.1 xref: UniProtKB:P11309 xref: UniProtKB:Q38RT9 xref: UniProtKB:Q96RG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011609 ! PIM1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0017765 ! pim1-bmx-5 physical interaction relationship: participates_in CCO:I0018344 ! pim1-bmx-4 physical interaction relationship: participates_in CCO:I0018345 ! pim1-bmx-7 physical interaction relationship: participates_in CCO:I0018675 ! pim1-bmx-6 physical interaction relationship: participates_in CCO:I0020169 ! shmt1-pim1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0022813 name: SRPK2_HUMAN def: "Serine/threonine-protein kinase SRPK2" [UniProtKB:P78362] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P78362] synonym: "Serine/arginine-rich protein-specific kinase 2" EXACT [UniProtKB:P78362] synonym: "SFRS protein kinase 2" EXACT [UniProtKB:P78362] synonym: "SR-protein-specific kinase 2" EXACT [UniProtKB:P78362] xref: EMBL:AAC05299.1 xref: EMBL:AAC29140.1 xref: EMBL:AAC29141.1 xref: EMBL:AAH35214.1 xref: EMBL:AAH68547.1 xref: EMBL:AAQ63886.1 xref: UniProtKB:O75220 xref: UniProtKB:O75221 xref: UniProtKB:P78362 xref: UniProtKB:Q6NUL0 xref: UniProtKB:Q6V1X2 xref: UniProtKB:Q8IYQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008224 ! SRPK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0035691 ! SRPK2_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0035692 ! SRPK2_HUMAN-Phosphotyrosine319 relationship: transforms_into CCO:B0035693 ! SRPK2_HUMAN-Phosphoserine588 relationship: transforms_into CCO:B0070929 ! SRPK2_HUMAN-Phosphoserine494 relationship: transforms_into CCO:B0070930 ! SRPK2_HUMAN-Phosphoserine497 [Term] id: CCO:B0022832 name: BCL6B_HUMAN def: "B-cell CLL/lymphoma 6 member B protein" [UniProtKB:Q8N143] synonym: "Bcl6-associated zinc finger protein" EXACT [UniProtKB:Q8N143] synonym: "Zinc finger protein 62" EXACT [UniProtKB:Q8N143] xref: EMBL:AAH59404.1 xref: EMBL:BAC00962.1 xref: EMBL:BAC00963.1 xref: UniProtKB:Q6PCB4 xref: UniProtKB:Q8N143 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011260 ! BCL6B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0022838 name: Q8NEI9_HUMAN def: "OR7E91P protein" [UniProtKB:Q8NEI9] xref: EMBL:AAH30991.1 xref: UniProtKB:Q8NEI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008434 ! OR7E91P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022839 name: Q8NHC0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHC0] xref: EMBL:BAC05715.1 xref: UniProtKB:Q8NHC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022840 name: Q8NH98_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH98] xref: EMBL:BAC05738.1 xref: UniProtKB:Q8NH98 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022842 name: Q8NH65_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH65] xref: EMBL:BAC05772.1 xref: UniProtKB:Q8NH65 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022843 name: Q9UPJ0_HUMAN def: "BC319430_7" [UniProtKB:Q9UPJ0] xref: EMBL:AAD03354.1 xref: UniProtKB:Q9UPJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022844 name: Q8WZ85_HUMAN def: "Olfactory-like receptor PJCG2" [UniProtKB:Q8WZ85] xref: EMBL:AAL32996.1 xref: UniProtKB:Q8WZ85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008899 ! PJCG2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022845 name: Q8NHB5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHB5] xref: EMBL:BAC05720.1 xref: UniProtKB:Q8NHB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022846 name: Q8NH97_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH97] xref: EMBL:BAC05740.1 xref: UniProtKB:Q8NH97 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022847 name: Q8NH99_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH99] xref: EMBL:BAC05737.1 xref: UniProtKB:Q8NH99 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022848 name: Q9P1R1_HUMAN def: "Putative taste receptor HTR2" [UniProtKB:Q9P1R1] xref: EMBL:AAF72204.1 xref: UniProtKB:Q9P1R1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008979 ! OR7E35P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022849 name: Q8NH46_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH46] xref: EMBL:BAC05793.1 xref: UniProtKB:Q8NH46 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022852 name: Q8NGT4_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGT4] xref: EMBL:BAC05921.1 xref: UniProtKB:Q8NGT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022854 name: Q8NHC1_HUMAN def: "Seven transmembrane helix receptor (HCG2002310)" [UniProtKB:Q8NHC1] xref: EMBL:BAC05712.1 xref: EMBL:EAW76456.1 xref: UniProtKB:Q8NHC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008886 ! hCG_2002310_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022856 name: Q8NGP1_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGP1] xref: EMBL:BAC05969.1 xref: UniProtKB:Q8NGP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022857 name: Q8NHB9_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHB9] xref: EMBL:BAC05716.1 xref: UniProtKB:Q8NHB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008885 ! OR7E85P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022858 name: Q8NH45_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH45] xref: EMBL:BAC05794.1 xref: UniProtKB:Q8NH45 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022861 name: O7E24_HUMAN def: "Olfactory receptor 7E24" [UniProtKB:Q6IFN5] synonym: "Olfactory receptor OR19-14" EXACT [UniProtKB:Q6IFN5] xref: EMBL:AAD03353.1 xref: EMBL:DAA04625.1 xref: UniProtKB:Q6IFN5 xref: UniProtKB:Q9UPJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007913 ! OR7E24_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022862 name: Q9UDD8_HUMAN def: "G protein-coupled receptor homolog clone G3" [UniProtKB:Q9UDD8] xref: UniProtKB:Q9UDD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022863 name: Q15618_HUMAN def: "Putative olfactory receptor" [UniProtKB:Q15618] xref: EMBL:CAA61820.1 xref: UniProtKB:Q15618 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008530 ! OR7E18P_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022865 name: Q8NHA1_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHA1] xref: EMBL:BAC05735.1 xref: UniProtKB:Q8NHA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022866 name: Q8NG89_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NG89] xref: EMBL:BAC06156.1 xref: UniProtKB:Q8NG89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008884 ! OR7E86P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022870 name: Q96N54_HUMAN xref: UniProtKB:Q96N54 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022873 name: Q8NGD7_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGD7] xref: EMBL:BAC06096.1 xref: UniProtKB:Q8NGD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0022898 name: GBRA4_HUMAN def: "Gamma-aminobutyric acid receptor subunit alpha-4 precursor" [UniProtKB:P48169] synonym: "GABA(A) receptor subunit alpha-4" EXACT [UniProtKB:P48169] xref: EMBL:AAA74743.1 xref: EMBL:AAB52519.1 xref: EMBL:AAH35055.1 xref: EMBL:BAG52228.1 xref: EMBL:EAW93029.1 xref: UniProtKB:P48169 xref: UniProtKB:Q8IYR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011419 ! GABRA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway relationship: transforms_into CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0043282 ! GBRA4_HUMAN-Phosphoserine142 [Term] id: CCO:B0022899 name: GBRR2_HUMAN def: "Gamma-aminobutyric acid receptor subunit rho-2 precursor" [UniProtKB:P28476] synonym: "GABA(A) receptor subunit rho-2" EXACT [UniProtKB:P28476] xref: EMBL:AAA52510.1 xref: EMBL:AAI30353.1 xref: EMBL:AAI30355.1 xref: EMBL:CAC07339.2 xref: UniProtKB:A2BDE4 xref: UniProtKB:P28476 xref: UniProtKB:Q9H153 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011432 ! GABRR2_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022900 name: GBRG3_HUMAN def: "Gamma-aminobutyric acid receptor subunit gamma-3 precursor" [UniProtKB:Q99928] synonym: "GABA(A) receptor subunit gamma-3" EXACT [UniProtKB:Q99928] xref: EMBL:AAB39369.1 xref: EMBL:AAF63215.1 xref: EMBL:AAF99698.1 xref: UniProtKB:Q99928 xref: UniProtKB:Q9HD46 xref: UniProtKB:Q9NYT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011429 ! GABRG3_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022901 name: GBRE_HUMAN def: "Gamma-aminobutyric acid receptor subunit epsilon precursor" [UniProtKB:P78334] synonym: "GABA(A) receptor subunit epsilon" EXACT [UniProtKB:P78334] xref: EMBL:AAB49284.1 xref: EMBL:AAB94645.1 xref: EMBL:CAA68914.1 xref: EMBL:CAA70903.1 xref: EMBL:CAA70904.1 xref: UniProtKB:O15345 xref: UniProtKB:O15346 xref: UniProtKB:P78334 xref: UniProtKB:Q99520 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011426 ! GABRE_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022902 name: Q8IYR7_HUMAN xref: UniProtKB:Q8IYR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022903 name: GBRT_HUMAN def: "Gamma-aminobutyric acid receptor subunit theta precursor" [UniProtKB:Q9UN88] synonym: "GABA(A) receptor subunit theta" EXACT [UniProtKB:Q9UN88] xref: EMBL:AAD51172.1 xref: EMBL:AAF70380.1 xref: EMBL:AAI09211.1 xref: EMBL:AAI09212.1 xref: UniProtKB:Q32MB4 xref: UniProtKB:Q9NZK8 xref: UniProtKB:Q9UN88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011433 ! GABRQ_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001559 ! neurotransmitter transporter activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022906 name: GBRG1_HUMAN def: "Gamma-aminobutyric acid receptor subunit gamma-1 precursor" [UniProtKB:Q8N1C3] synonym: "GABA(A) receptor subunit gamma-1" EXACT [UniProtKB:Q8N1C3] xref: EMBL:AAH31087.1 xref: EMBL:BAG53758.1 xref: EMBL:CAI45936.1 xref: EMBL:EAW93021.1 xref: UniProtKB:Q5H9T8 xref: UniProtKB:Q8N1C3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011427 ! GABRG1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022907 name: GBRA6_HUMAN def: "Gamma-aminobutyric acid receptor subunit alpha-6 precursor" [UniProtKB:Q16445] synonym: "GABA(A) receptor subunit alpha-6" EXACT [UniProtKB:Q16445] xref: EMBL:AAB36480.1 xref: EMBL:AAH96241.1 xref: EMBL:AAH96242.1 xref: EMBL:AAH99640.1 xref: EMBL:AAH99641.1 xref: UniProtKB:Q16445 xref: UniProtKB:Q4VAV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011421 ! GABRA6_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001957 ! benzodiazepine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022908 name: Q5H9T8_HUMAN xref: UniProtKB:Q5H9T8 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022909 name: GBRG2_HUMAN def: "Gamma-aminobutyric acid receptor subunit gamma-2 precursor" [UniProtKB:P18507] synonym: "GABA(A) receptor subunit gamma-2" EXACT [UniProtKB:P18507] xref: EMBL:AAD50273.1 xref: EMBL:AAH69348.1 xref: EMBL:AAH74795.1 xref: EMBL:CAA33437.1 xref: UniProtKB:P18507 xref: UniProtKB:Q6GRL6 xref: UniProtKB:Q9UN15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011428 ! GABRG2_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001957 ! benzodiazepine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022911 name: GLRB_HUMAN def: "Glycine receptor subunit beta precursor" [UniProtKB:P48167] synonym: "Glycine receptor 58 kDa subunit" EXACT [UniProtKB:P48167] xref: EMBL:AAB37750.1 xref: EMBL:AAC71033.1 xref: EMBL:AAC71034.1 xref: EMBL:AAH32635.1 xref: UniProtKB:P48167 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011440 ! GLRB_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003209 ! glycine binding relationship: has_function CCO:F0003475 ! extracellular-glycine-gated ion channel activity relationship: has_function CCO:F0003476 ! extracellular-glycine-gated chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0022913 name: GLRA1_HUMAN def: "Glycine receptor subunit alpha-1 precursor" [UniProtKB:P23415] synonym: "Glycine receptor 48 kDa subunit" EXACT [UniProtKB:P23415] synonym: "Glycine receptor strychnine-binding subunit" EXACT [UniProtKB:P23415] xref: EMBL:AAH74980.1 xref: EMBL:AAI14948.1 xref: EMBL:CAA36258.1 xref: UniProtKB:P23415 xref: UniProtKB:Q14C77 xref: UniProtKB:Q6DJV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011437 ! GLRA1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003209 ! glycine binding relationship: has_function CCO:F0003476 ! extracellular-glycine-gated chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004615 ! taurine binding relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: located_in CCO:C0002129 ! intracellular membrane-bounded organelle relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0003173 ! negative regulation of transmission of nerve impulse [Term] id: CCO:B0022914 name: GBRA1_HUMAN def: "Gamma-aminobutyric acid receptor subunit alpha-1 precursor" [UniProtKB:P14867] synonym: "GABA(A) receptor subunit alpha-1" EXACT [UniProtKB:P14867] xref: EMBL:AAH30696.1 xref: EMBL:CAA31925.1 xref: EMBL:CAA32874.1 xref: UniProtKB:P14867 xref: UniProtKB:Q8N629 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011416 ! GABRA1_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway relationship: transforms_into CCO:B0039440 ! GBRA1_HUMAN-Phosphotyrosine368 relationship: transforms_into CCO:B0039441 ! GBRA1_HUMAN-Phosphotyrosine375 [Term] id: CCO:B0022915 name: GBRA5_HUMAN def: "Gamma-aminobutyric acid receptor subunit alpha-5 precursor" [UniProtKB:P31644] synonym: "GABA(A) receptor subunit alpha-5" EXACT [UniProtKB:P31644] xref: EMBL:AAA58490.1 xref: EMBL:AAC31809.1 xref: EMBL:AAF62508.1 xref: EMBL:AAF62509.1 xref: EMBL:AAF62510.1 xref: EMBL:AAI11980.1 xref: EMBL:AAI13423.1 xref: EMBL:AAP88832.1 xref: UniProtKB:P31644 xref: UniProtKB:Q14DC2 xref: UniProtKB:Q53XL6 xref: UniProtKB:Q9NYT3 xref: UniProtKB:Q9NYT4 xref: UniProtKB:Q9NYT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011420 ! GABRA5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022917 name: GLRA2_HUMAN def: "Glycine receptor subunit alpha-2 precursor" [UniProtKB:P23416] xref: EMBL:AAB38272.1 xref: EMBL:AAB38273.1 xref: EMBL:AAC35290.1 xref: EMBL:AAH32864.1 xref: EMBL:AAR87842.1 xref: EMBL:AAR87843.1 xref: EMBL:CAA36257.1 xref: EMBL:CAG29339.1 xref: UniProtKB:P23416 xref: UniProtKB:Q53YX7 xref: UniProtKB:Q6ICQ0 xref: UniProtKB:Q99862 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011438 ! GLRA2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001243 ! glycine-inhibited chloride channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0003209 ! glycine binding relationship: has_function CCO:F0003476 ! extracellular-glycine-gated chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0020561 ! glra2-bat3 physical interaction relationship: participates_in CCO:I0020562 ! glra2-gpr108 physical interaction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0022924 name: GBRA2_HUMAN def: "Gamma-aminobutyric acid receptor subunit alpha-2 precursor" [UniProtKB:P47869] synonym: "GABA(A) receptor subunit alpha-2" EXACT [UniProtKB:P47869] xref: EMBL:AAB27278.1 xref: EMBL:BAD92532.1 xref: UniProtKB:P47869 xref: UniProtKB:Q59G14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011417 ! GABRA2_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001957 ! benzodiazepine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000994 ! integral to synaptic vesicle membrane relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022926 name: GBRR1_HUMAN def: "Gamma-aminobutyric acid receptor subunit rho-1 precursor" [UniProtKB:P24046] synonym: "GABA(A) receptor subunit rho-1" EXACT [UniProtKB:P24046] xref: EMBL:AAA52509.1 xref: EMBL:CAC36328.2 xref: EMBL:CAI16246.1 xref: UniProtKB:P24046 xref: UniProtKB:Q9BX06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011431 ! GABRR1_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022931 name: GBRD_HUMAN def: "Gamma-aminobutyric acid receptor subunit delta precursor" [UniProtKB:O14764] synonym: "GABA(A) receptor subunit delta" EXACT [UniProtKB:O14764] xref: EMBL:AAB70007.1 xref: EMBL:AAH33801.1 xref: EMBL:CAI15436.1 xref: UniProtKB:O14764 xref: UniProtKB:Q8N4N9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011425 ! GABRD_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0015117 ! gabrd-ubqln1 physical interaction relationship: participates_in CCO:I0017531 ! gabrd-ubqln4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0022933 name: GBRA3_HUMAN def: "Gamma-aminobutyric acid receptor subunit alpha-3 precursor" [UniProtKB:P34903] synonym: "GABA(A) receptor subunit alpha-3" EXACT [UniProtKB:P34903] xref: EMBL:AAB27279.1 xref: EMBL:AAG12455.1 xref: EMBL:AAH28629.1 xref: UniProtKB:P34903 xref: UniProtKB:Q8TAF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011418 ! GABRA3_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001957 ! benzodiazepine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway relationship: transforms_into CCO:B0039442 ! GBRA3_HUMAN-Phosphoserine433 [Term] id: CCO:B0022935 name: Q6PCC3_HUMAN def: "Gamma-aminobutyric acid (GABA) A receptor, gamma 2" [UniProtKB:Q6PCC3] xref: EMBL:AAH59389.1 xref: UniProtKB:Q6PCC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011428 ! GABRG2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0022936 name: Q5TEW3_HUMAN def: "Breast cancer anti-estrogen resistance 3 (Breast cancer anti-estrogen resistance 3, isoform CRA_c)" [UniProtKB:Q5TEW3] xref: EMBL:CAI18951.1 xref: EMBL:EAW73068.1 xref: UniProtKB:Q5TEW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004147 ! BCAR3_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0022985 name: FGF17_HUMAN def: "Fibroblast growth factor 17 precursor" [UniProtKB:O60258] synonym: "FGF-17" EXACT [UniProtKB:O60258] xref: EMBL:AAH69475.1 xref: EMBL:AAI05132.1 xref: EMBL:AAI13490.1 xref: EMBL:AAM09570.1 xref: EMBL:AAQ89228.1 xref: EMBL:BAA25429.1 xref: UniProtKB:O60258 xref: UniProtKB:Q2M2W1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017795 ! FGF17_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0022986 name: FGF18_HUMAN def: "Fibroblast growth factor 18 precursor" [UniProtKB:O76093] synonym: "FGF-18" EXACT [UniProtKB:O76093] synonym: "zFGF5" EXACT [UniProtKB:O76093] xref: EMBL:AAC62240.1 xref: EMBL:AAF22977.1 xref: EMBL:AAH06245.1 xref: EMBL:AAQ89954.1 xref: EMBL:AAV38377.1 xref: EMBL:AAV38378.1 xref: EMBL:BAA31986.1 xref: UniProtKB:O76093 xref: UniProtKB:Q6UWF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017796 ! FGF18_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0001356 ! positive regulation of vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:B0022999 name: PTPRK_HUMAN def: "Receptor-type tyrosine-protein phosphatase kappa precursor" [UniProtKB:Q15262] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q15262] synonym: "Protein-tyrosine phosphatase kappa" EXACT [UniProtKB:Q15262] synonym: "R-PTP-kappa" EXACT [UniProtKB:Q15262] xref: EMBL:AAC37599.1 xref: EMBL:CAA94519.1 xref: EMBL:CAI21517.1 xref: EMBL:CAI23055.1 xref: EMBL:CAI39440.1 xref: EMBL:CAI40501.1 xref: EMBL:CAI41224.1 xref: EMBL:CAI42412.1 xref: EMBL:CAI43013.1 xref: UniProtKB:Q14763 xref: UniProtKB:Q15262 xref: UniProtKB:Q5TG10 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022543 ! PTPRK_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0016094 ! gadd45g-ptprk physical interaction relationship: participates_in CCO:I0020197 ! tk1-ptprk physical interaction [Term] id: CCO:B0023006 name: PTPRT_HUMAN def: "Receptor-type tyrosine-protein phosphatase T precursor" [UniProtKB:O14522] synonym: "EC 3.1.3.48" EXACT [UniProtKB:O14522] synonym: "R-PTP-T" EXACT [UniProtKB:O14522] synonym: "RPTP-rho" EXACT [UniProtKB:O14522] xref: EMBL:AAD09421.2 xref: EMBL:BAA22952.2 xref: EMBL:CAH72553.1 xref: EMBL:CAH72555.1 xref: EMBL:CAI19251.1 xref: EMBL:CAI19253.1 xref: EMBL:CAI19865.1 xref: EMBL:CAI19867.1 xref: EMBL:CAI19877.1 xref: EMBL:CAI19879.1 xref: EMBL:CAI19981.1 xref: EMBL:CAI19983.1 xref: EMBL:CAI20437.1 xref: EMBL:CAI20439.1 xref: EMBL:CAI22489.1 xref: EMBL:CAI22491.1 xref: EMBL:CAI22909.1 xref: EMBL:CAI22911.1 xref: EMBL:CAI23310.1 xref: EMBL:CAI23312.1 xref: UniProtKB:O14522 xref: UniProtKB:O43655 xref: UniProtKB:O75664 xref: UniProtKB:Q5W0X9 xref: UniProtKB:Q5W0Y1 xref: UniProtKB:Q9BR24 xref: UniProtKB:Q9BR28 xref: UniProtKB:Q9H0Y8 xref: UniProtKB:Q9NTL1 xref: UniProtKB:Q9NU72 xref: UniProtKB:Q9UBD2 xref: UniProtKB:Q9UJL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019553 ! PTPRT_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015961 ! ptprn-ptprt-2 physical interaction relationship: participates_in CCO:I0016312 ! ptprn-ptprt-3 physical interaction relationship: participates_in CCO:I0017763 ! ptprn-ptprt-1 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0023019 name: PTPRU_HUMAN def: "Receptor-type tyrosine-protein phosphatase U precursor" [UniProtKB:Q92729] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q92729] synonym: "Pancreatic carcinoma phosphatase 2" EXACT [UniProtKB:Q92729] synonym: "PCP-2" EXACT [UniProtKB:Q92729] synonym: "Protein-tyrosine phosphatase J" EXACT [UniProtKB:Q92729] synonym: "PTP-J" EXACT [UniProtKB:Q92729] synonym: "R-PTP-U" EXACT [UniProtKB:Q92729] xref: EMBL:CAA65832.1 xref: UniProtKB:Q92729 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019554 ! PTPRU_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000725 ! transmembrane receptor protein tyrosine phosphatase signaling pathway [Term] id: CCO:B0023033 name: A2A2D2_HUMAN def: "Stathmin" [UniProtKB:A2A2D2] xref: EMBL:CAM12865.1 xref: UniProtKB:A2A2D2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005696 ! STMN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0023034 name: STMN2_HUMAN def: "Stathmin-2" [UniProtKB:Q93045] synonym: "Protein SCG10" EXACT [UniProtKB:Q93045] synonym: "Superior cervical ganglion-10 protein" EXACT [UniProtKB:Q93045] xref: EMBL:AAB36428.1 xref: EMBL:AAH06302.1 xref: EMBL:AAV38837.1 xref: EMBL:BAA23326.1 xref: EMBL:CAG33114.1 xref: UniProtKB:O14952 xref: UniProtKB:Q6PK68 xref: UniProtKB:Q93045 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008247 ! STMN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015406 ! stmn2-tex11 physical interaction relationship: participates_in CCO:I0019422 ! stmn2-tex11-1 physical interaction relationship: participates_in CCO:I0019843 ! stmn2-eef1a1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0035712 ! STMN2_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0035713 ! STMN2_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0035714 ! STMN2_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0035715 ! STMN2_HUMAN-Phosphoserine73 relationship: transforms_into CCO:B0035716 ! STMN2_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0035717 ! STMN2_HUMAN-Phosphoserine97 [Term] id: CCO:B0023035 name: A2A2D0_HUMAN def: "Stathmin" [UniProtKB:A2A2D0] xref: EMBL:CAM12864.1 xref: UniProtKB:A2A2D0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005696 ! STMN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0023036 name: Q59G27_HUMAN def: "Stathmin" [UniProtKB:Q59G27] xref: EMBL:BAD92519.1 xref: UniProtKB:Q59G27 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0023038 name: STMN4_HUMAN def: "Stathmin-4" [UniProtKB:Q9H169] synonym: "RB3" EXACT [UniProtKB:Q9H169] synonym: "Stathmin-like protein B3" EXACT [UniProtKB:Q9H169] xref: EMBL:AAH11520.1 xref: EMBL:AAI11002.1 xref: EMBL:CAB66503.1 xref: EMBL:CAC22254.1 xref: UniProtKB:Q2TAB9 xref: UniProtKB:Q9H169 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008249 ! STMN4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020460 ! stmn4-immt physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0023039 name: STMN3_HUMAN def: "Stathmin-3" [UniProtKB:Q9NZ72] synonym: "SCG10-like protein" EXACT [UniProtKB:Q9NZ72] xref: EMBL:AAD12730.1 xref: EMBL:AAF35245.1 xref: EMBL:AAH09381.1 xref: EMBL:AAH25234.1 xref: EMBL:CAC16222.1 xref: UniProtKB:O75527 xref: UniProtKB:Q969Y4 xref: UniProtKB:Q9NZ72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008248 ! STMN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001585 ! regulation of Rac GTPase activity relationship: participates_in CCO:P0001983 ! negative regulation of Rac protein signal transduction relationship: participates_in CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis relationship: transforms_into CCO:B0035718 ! STMN3_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0035719 ! STMN3_HUMAN-Phosphoserine68 relationship: transforms_into CCO:B0035720 ! STMN3_HUMAN-Phosphoserine73 [Term] id: CCO:B0023063 name: IF2M_HUMAN def: "Translation initiation factor IF-2, mitochondrial precursor" [UniProtKB:P46199] synonym: "IF-2(Mt)" EXACT [UniProtKB:P46199] synonym: "IF-2Mt" EXACT [UniProtKB:P46199] synonym: "IF2(mt)" EXACT [UniProtKB:P46199] xref: EMBL:AAA67038.1 xref: EMBL:AAM14617.1 xref: EMBL:AAM70196.1 xref: UniProtKB:P46199 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018223 ! MTIF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0017173 ! nfkbib-mtif2 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0067010 ! IF2M_HUMAN-Phosphothreonine688 [Term] id: CCO:B0023090 name: TMLH_HUMAN def: "Trimethyllysine dioxygenase, mitochondrial precursor" [UniProtKB:Q9NVH6] synonym: "EC 1.14.11.8" EXACT [UniProtKB:Q9NVH6] synonym: "Epsilon-trimethyllysine 2-oxoglutarate dioxygenase" EXACT [UniProtKB:Q9NVH6] synonym: "TML dioxygenase" EXACT [UniProtKB:Q9NVH6] synonym: "TML hydroxylase" EXACT [UniProtKB:Q9NVH6] synonym: "TML-alpha-ketoglutarate dioxygenase" EXACT [UniProtKB:Q9NVH6] synonym: "TMLD" EXACT [UniProtKB:Q9NVH6] xref: EMBL:AAH25269.1 xref: EMBL:AAL01871.1 xref: EMBL:BAA91775.1 xref: EMBL:CAG33546.1 xref: EMBL:CAH71441.1 xref: EMBL:CAH71442.1 xref: EMBL:CAL38074.1 xref: UniProtKB:Q5TZB5 xref: UniProtKB:Q6IA90 xref: UniProtKB:Q8TBT0 xref: UniProtKB:Q9NVH6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022720 ! TMLHE_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0007705 ! trimethyllysine dioxygenase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction [Term] id: CCO:B0023169 name: A6NMR0_HUMAN def: "Putative uncharacterized protein PAM" [UniProtKB:A6NMR0] xref: UniProtKB:A6NMR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007231 ! PAM_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0000901 ! peptidylglycine monooxygenase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000887 ! cellular process [Term] id: CCO:B0023175 name: AMD_HUMAN def: "Peptidyl-glycine alpha-amidating monooxygenase precursor" [UniProtKB:P19021] synonym: "PAM" EXACT [UniProtKB:P19021] xref: EMBL:AAA36414.1 xref: EMBL:AAB32775.1 xref: EMBL:AAB32776.1 xref: EMBL:AAD01439.1 xref: EMBL:AAH18127.1 xref: EMBL:AAP36087.1 xref: UniProtKB:O95080 xref: UniProtKB:P19021 xref: UniProtKB:Q16252 xref: UniProtKB:Q16253 xref: UniProtKB:Q86U53 xref: UniProtKB:Q8WVC7 xref: UniProtKB:Q9UCG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007231 ! PAM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000887 ! cellular process relationship: transforms_into CCO:B0034531 ! AMD_HUMAN-Phosphoserine918 relationship: transforms_into CCO:B0034532 ! AMD_HUMAN-Phosphoserine955 relationship: transforms_into CCO:B0034533 ! AMD_HUMAN-Phosphoserine957 relationship: transforms_into CCO:B0034534 ! AMD_HUMAN-Sulfotyrosine961 [Term] id: CCO:B0023179 name: NPTN_HUMAN def: "Neuroplastin precursor" [UniProtKB:Q9Y639] synonym: "SDR-1" EXACT [UniProtKB:Q9Y639] synonym: "Stromal cell-derived receptor 1" EXACT [UniProtKB:Q9Y639] xref: EMBL:AAD43217.1 xref: EMBL:AAD43218.1 xref: EMBL:AAI05980.1 xref: EMBL:AAI17463.1 xref: EMBL:BAD93049.1 xref: UniProtKB:Q17R52 xref: UniProtKB:Q59EJ9 xref: UniProtKB:Q6NVX7 xref: UniProtKB:Q9Y639 xref: UniProtKB:Q9Y640 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018840 ! NPTN_human relationship: has_function CCO:F0008023 ! cell adhesion molecule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: participates_in CCO:P0002787 ! positive regulation of long-term neuronal synaptic plasticity [Term] id: CCO:B0023192 name: SMD1_HUMAN def: "Small nuclear ribonucleoprotein Sm D1" [UniProtKB:P62314] synonym: "Sm-D autoantigen" EXACT [UniProtKB:P62314] synonym: "Sm-D1" EXACT [UniProtKB:P62314] synonym: "snRNP core protein D1" EXACT [UniProtKB:P62314] xref: EMBL:AAA36620.1 xref: EMBL:AAA85339.1 xref: EMBL:AAH01721.1 xref: EMBL:AAH72427.1 xref: EMBL:CAG47035.1 xref: UniProtKB:P13641 xref: UniProtKB:P62314 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008190 ! SNRPD1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction [Term] id: CCO:B0023202 name: Q53FK0_HUMAN def: "MutS homolog 2 variant" [UniProtKB:Q53FK0] xref: EMBL:BAD97004.1 xref: UniProtKB:Q53FK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001438 ! MutSalpha complex relationship: located_in CCO:C0001439 ! MutSbeta complex relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0023207 name: Q5JQZ9_HUMAN def: "Cell division cycle 2-like 6 (CDK8-like)" [UniProtKB:Q5JQZ9] xref: EMBL:CAI40283.1 xref: EMBL:CAI41173.1 xref: UniProtKB:Q5JQZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004276 ! CDC2L6_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0023306 name: DLG3_HUMAN def: "Disks large homolog 3" [UniProtKB:Q92796] synonym: "Neuroendocrine-DLG" EXACT [UniProtKB:Q92796] synonym: "SAP102" EXACT [UniProtKB:Q92796] synonym: "Synapse-associated protein 102" EXACT [UniProtKB:Q92796] synonym: "XLMR" EXACT [UniProtKB:Q92796] xref: EMBL:AAB61453.1 xref: EMBL:BAA86546.1 xref: UniProtKB:Q92796 xref: UniProtKB:Q9ULI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007461 ! DLG3_human relationship: has_function CCO:F0000802 ! guanylate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0018350 ! abca1-dgl3 physical interaction relationship: participates_in CCO:I0018860 ! erbb4-dlg3-1 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0034699 ! DLG3_HUMAN-Phosphotyrosine673 relationship: transforms_into CCO:B0064769 ! DLG3_HUMAN-Phosphotyrosine808 [Term] id: CCO:B0023311 name: DLG4_HUMAN def: "Disks large homolog 4" [UniProtKB:P78352] synonym: "Postsynaptic density protein 95" EXACT [UniProtKB:P78352] synonym: "PSD-95" EXACT [UniProtKB:P78352] synonym: "SAP90" EXACT [UniProtKB:P78352] synonym: "Synapse-associated protein 90" EXACT [UniProtKB:P78352] xref: EMBL:AAB07736.1 xref: EMBL:AAC52113.1 xref: EMBL:AAD56173.1 xref: UniProtKB:P78352 xref: UniProtKB:Q92941 xref: UniProtKB:Q9UKK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007462 ! DLG4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018311 ! erbb4-dlg4-5 physical interaction relationship: participates_in CCO:I0018355 ! erbb4-dlg4-3 physical interaction relationship: participates_in CCO:I0018397 ! erbb4-dlg4 physical interaction relationship: participates_in CCO:I0018857 ! erbb4-dlg4-1 physical interaction relationship: participates_in CCO:I0019250 ! erbb4-dlg4-4 physical interaction relationship: participates_in CCO:I0019285 ! erbb4-dlg4-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0034700 ! DLG4_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0034701 ! DLG4_HUMAN-Phosphotyrosine240 relationship: transforms_into CCO:B0034702 ! DLG4_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0034703 ! DLG4_HUMAN-Phosphotyrosine397 relationship: transforms_into CCO:B0034704 ! DLG4_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0034705 ! DLG4_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0034706 ! DLG4_HUMAN-Phosphotyrosine432 relationship: transforms_into CCO:B0034707 ! DLG4_HUMAN-Phosphotyrosine580 relationship: transforms_into CCO:B0034708 ! DLG4_HUMAN-Phosphotyrosine604 relationship: transforms_into CCO:B0034709 ! DLG4_HUMAN-Phosphotyrosine715 relationship: transforms_into CCO:B0052358 ! DLG4_HUMAN-Phosphotyrosine701 [Term] id: CCO:B0023320 name: DLG2_HUMAN def: "Disks large homolog 2" [UniProtKB:Q15700] synonym: "Channel-associated protein of synapse-110" EXACT [UniProtKB:Q15700] synonym: "Chapsyn-110" EXACT [UniProtKB:Q15700] synonym: "Postsynaptic density protein PSD-93" EXACT [UniProtKB:Q15700] xref: EMBL:AAB04949.1 xref: EMBL:BAC86685.1 xref: EMBL:BAD92489.1 xref: EMBL:CAH18680.1 xref: UniProtKB:Q15700 xref: UniProtKB:Q59G57 xref: UniProtKB:Q68CQ8 xref: UniProtKB:Q6ZTA8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008470 ! DLG2_human relationship: has_function CCO:F0000802 ! guanylate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0018361 ! abca1-dig2 physical interaction relationship: participates_in CCO:I0018859 ! erbb4-dlg2-1 physical interaction relationship: transforms_into CCO:B0039391 ! DLG2_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0039392 ! DLG2_HUMAN-Phosphotyrosine58 relationship: transforms_into CCO:B0039393 ! DLG2_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0039394 ! DLG2_HUMAN-Phosphoserine175 relationship: transforms_into CCO:B0039395 ! DLG2_HUMAN-Phosphotyrosine340 relationship: transforms_into CCO:B0039396 ! DLG2_HUMAN-Phosphotyrosine348 relationship: transforms_into CCO:B0039397 ! DLG2_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0039398 ! DLG2_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0039399 ! DLG2_HUMAN-Phosphoserine414 relationship: transforms_into CCO:B0039400 ! DLG2_HUMAN-Phosphotyrosine500 relationship: transforms_into CCO:B0039401 ! DLG2_HUMAN-Phosphotyrosine505 relationship: transforms_into CCO:B0039402 ! DLG2_HUMAN-Phosphotyrosine750 relationship: transforms_into CCO:B0039403 ! DLG2_HUMAN-Phosphotyrosine755 [Term] id: CCO:B0023340 name: Q59H84_HUMAN def: "Septin" [UniProtKB:Q59H84] xref: EMBL:BAD92112.1 xref: UniProtKB:Q59H84 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0023347 name: Q9H9P7_HUMAN def: "Septin" [UniProtKB:Q9H9P7] xref: EMBL:BAB14176.1 xref: UniProtKB:Q9H9P7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0023348 name: Q8NFH9_HUMAN def: "Septin" [UniProtKB:Q8NFH9] xref: EMBL:AAM82548.1 xref: UniProtKB:Q8NFH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0023351 name: Q6B514_HUMAN def: "Septin" [UniProtKB:Q6B514] xref: EMBL:AAT80339.1 xref: UniProtKB:Q6B514 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0023365 name: PPRC1_HUMAN def: "Peroxisome proliferator-activated receptor gamma coactivator-related protein 1" [UniProtKB:Q5VV67] synonym: "PGC-1-related coactivator" EXACT [UniProtKB:Q5VV67] synonym: "PRC" EXACT [UniProtKB:Q5VV67] xref: EMBL:AAH02561.2 xref: EMBL:AAH63806.1 xref: EMBL:AAH63829.1 xref: EMBL:AAK11573.1 xref: EMBL:BAA25521.2 xref: EMBL:CAH72218.1 xref: EMBL:CAH72219.1 xref: UniProtKB:Q5VV66 xref: UniProtKB:Q5VV67 xref: UniProtKB:Q6P3U5 xref: UniProtKB:Q6P3W1 xref: UniProtKB:Q76N31 xref: UniProtKB:Q9BUJ3 xref: UniProtKB:Q9BZE5 xref: UniProtKB:Q9Y4E0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008008 ! PPRC1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0023371 name: HIC2_HUMAN def: "Hypermethylated in cancer 2 protein" [UniProtKB:Q96JB3] synonym: "Hic-2" EXACT [UniProtKB:Q96JB3] synonym: "Hic-3" EXACT [UniProtKB:Q96JB3] synonym: "HIC1-related gene on chromosome 22" EXACT [UniProtKB:Q96JB3] synonym: "Zinc finger and BTB domain-containing protein 30" EXACT [UniProtKB:Q96JB3] xref: EMBL:AAH94787.1 xref: EMBL:AAK72951.1 xref: EMBL:BAA82972.2 xref: EMBL:CAB82344.1 xref: EMBL:CAC70715.1 xref: EMBL:CAG30263.1 xref: UniProtKB:Q504T6 xref: UniProtKB:Q96JB3 xref: UniProtKB:Q96KR3 xref: UniProtKB:Q9NSM9 xref: UniProtKB:Q9UPX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007620 ! HIC2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020623 ! pdk2-hic2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0023418 name: STAT4_HUMAN def: "Signal transducer and activator of transcription 4" [UniProtKB:Q14765] xref: EMBL:AAB05605.1 xref: EMBL:AAH31212.1 xref: EMBL:AAL12164.1 xref: UniProtKB:Q14765 xref: UniProtKB:Q96NZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020066 ! STAT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019481 ! nmi-stat4-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070967 ! STAT4_HUMAN-Phosphotyrosine693 relationship: transforms_into CCO:B0070968 ! STAT4_HUMAN-Phosphoserine721 [Term] id: CCO:B0023422 name: STAT2_HUMAN def: "Signal transducer and activator of transcription 2" [UniProtKB:P52630] synonym: "p113" EXACT [UniProtKB:P52630] xref: EMBL:AAA98760.1 xref: EMBL:AAB36226.1 xref: EMBL:AAB36227.1 xref: EMBL:AAH51284.1 xref: EMBL:AAS00091.1 xref: UniProtKB:P52630 xref: UniProtKB:Q16430 xref: UniProtKB:Q16431 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020065 ! STAT2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001376 ! hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070965 ! STAT2_HUMAN-Phosphotyrosine690 [Term] id: CCO:B0023430 name: Q67C41_HUMAN def: "Signal transducer and activator of transcription 1 variant a" [UniProtKB:Q67C41] xref: EMBL:AAR13284.1 xref: UniProtKB:Q67C41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005686 ! STAT1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0023489 name: SI1L2_HUMAN def: "Signal-induced proliferation-associated 1-like protein 2" [UniProtKB:Q9P2F8] synonym: "SIPA1-like protein 2" EXACT [UniProtKB:Q9P2F8] xref: EMBL:AAH13119.1 xref: EMBL:AAH82251.1 xref: EMBL:BAA92627.1 xref: EMBL:BAB14273.1 xref: EMBL:BAC04090.1 xref: EMBL:CAH73408.1 xref: EMBL:CAH73409.1 xref: EMBL:CAI22919.1 xref: EMBL:CAI22920.1 xref: UniProtKB:Q5VXR7 xref: UniProtKB:Q5VXR8 xref: UniProtKB:Q641Q4 xref: UniProtKB:Q8NA38 xref: UniProtKB:Q96DZ3 xref: UniProtKB:Q9H9F6 xref: UniProtKB:Q9P2F8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008184 ! SIPA1L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0035657 ! SI1L2_HUMAN-Phosphoserine1406 relationship: transforms_into CCO:B0052777 ! SI1L2_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0052778 ! SI1L2_HUMAN-Phosphoserine1478 relationship: transforms_into CCO:B0070528 ! SI1L2_HUMAN-Phosphoserine1029 relationship: transforms_into CCO:B0070529 ! SI1L2_HUMAN-Phosphoserine1488 [Term] id: CCO:B0023496 name: A4D2B3_HUMAN def: "TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa" [UniProtKB:A4D2B3] xref: EMBL:EAL23852.1 xref: UniProtKB:A4D2B3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008417 ! TAF6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0003021 ! regulation of transcription factor activity [Term] id: CCO:B0023501 name: TAF6L_HUMAN def: "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L" [UniProtKB:Q9Y6J9] synonym: "PAF65-alpha" EXACT [UniProtKB:Q9Y6J9] synonym: "PCAF-associated factor 65 alpha" EXACT [UniProtKB:Q9Y6J9] xref: EMBL:AAC39905.1 xref: UniProtKB:Q96HA6 xref: UniProtKB:Q9Y6J9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020138 ! TAF6L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015086 ! stx11-taf6l physical interaction relationship: participates_in CCO:I0017589 ! taf6l-taf9 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003021 ! regulation of transcription factor activity relationship: transforms_into CCO:B0071100 ! TAF6L_HUMAN-Phosphoserine85 [Term] id: CCO:B0023521 name: CD2_HUMAN def: "T-cell surface antigen CD2 precursor" [UniProtKB:P06729] synonym: "CD2 antigen" EXACT [UniProtKB:P06729] synonym: "Erythrocyte receptor" EXACT [UniProtKB:P06729] synonym: "LFA-2" EXACT [UniProtKB:P06729] synonym: "LFA-3 receptor" EXACT [UniProtKB:P06729] synonym: "Rosette receptor" EXACT [UniProtKB:P06729] synonym: "T-cell surface antigen T11/Leu-5" EXACT [UniProtKB:P06729] xref: EMBL:AAA35571.1 xref: EMBL:AAA51738.1 xref: EMBL:AAA51946.1 xref: EMBL:AAA53095.1 xref: EMBL:AAH33583.1 xref: EMBL:CAA30721.1 xref: EMBL:CAC14840.1 xref: UniProtKB:P06729 xref: UniProtKB:Q96TE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017295 ! CD2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001350 ! positive regulation of myeloid dendritic cell activation relationship: participates_in CCO:P0002394 ! regulation of T cell differentiation [Term] id: CCO:B0023550 name: RAB5C_HUMAN def: "Ras-related protein Rab-5C" [UniProtKB:P51148] synonym: "L1880" EXACT [UniProtKB:P51148] synonym: "RAB5L" EXACT [UniProtKB:P51148] xref: EMBL:AAA74081.1 xref: EMBL:AAB08927.1 xref: EMBL:AAF66594.1 xref: EMBL:AAI06040.1 xref: EMBL:AAI14440.1 xref: EMBL:AAM21086.1 xref: EMBL:AAV38291.1 xref: EMBL:CAG46699.1 xref: EMBL:EAW60805.1 xref: UniProtKB:P51148 xref: UniProtKB:Q6FH55 xref: UniProtKB:Q9P0Y5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008046 ! RAB5C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: located_in CCO:C0001339 ! early endosome membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:B0023551 name: RAB5A_HUMAN def: "Ras-related protein Rab-5A" [UniProtKB:P20339] xref: EMBL:AAA60245.1 xref: EMBL:AAH01267.1 xref: EMBL:AAH18288.1 xref: EMBL:AAM21084.1 xref: UniProtKB:P20339 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008044 ! RAB5A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: located_in CCO:C0001339 ! early endosome membrane relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:I0016229 ! rab5-eea1-1 physical interaction relationship: participates_in CCO:I0017986 ! eea1-rab5a-1 physical interaction relationship: participates_in CCO:I0018705 ! rab5a-rabep1-1 direct interaction relationship: participates_in CCO:I0018772 ! eea1-rab5a-2 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0023553 name: RAB5B_HUMAN def: "Ras-related protein Rab-5B" [UniProtKB:P61020] xref: EMBL:AAH32740.1 xref: EMBL:AAH40143.1 xref: EMBL:AAH50558.2 xref: EMBL:AAH56422.2 xref: EMBL:AAH65298.2 xref: EMBL:AAM21085.1 xref: EMBL:CAA38653.1 xref: EMBL:CAD97650.1 xref: UniProtKB:P35239 xref: UniProtKB:P35277 xref: UniProtKB:P61020 xref: UniProtKB:Q6PIK9 xref: UniProtKB:Q86TH0 xref: UniProtKB:Q8IXL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008045 ! RAB5B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: located_in CCO:C0001339 ! early endosome membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0017985 ! eea1-rab5b-1 physical interaction relationship: participates_in CCO:I0018593 ! eea1-rab5b-2 physical interaction relationship: participates_in CCO:I0018594 ! eea1-rab5b-3 colocalization relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:B0023606 name: PSDE_HUMAN def: "26S proteasome non-ATPase regulatory subunit 14" [UniProtKB:O00487] synonym: "26S proteasome regulatory subunit rpn11" EXACT [UniProtKB:O00487] synonym: "26S proteasome-associated PAD1 homolog 1" EXACT [UniProtKB:O00487] xref: EMBL:AAC51866.1 xref: EMBL:AAH66336.1 xref: UniProtKB:O00176 xref: UniProtKB:O00487 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008028 ! PSMD14_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008807 ! psmd14-plekhb2 physical interaction relationship: participates_in CCO:I0008822 ! psmd14-flj10324 physical interaction relationship: participates_in CCO:I0008823 ! psmd14-rbm15b physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035484 ! PSDE_HUMAN-Phosphotyrosine32 relationship: transforms_into CCO:B0035485 ! PSDE_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0041329 ! PSDE_HUMAN-Phosphoserine150 [Term] id: CCO:B0023650 name: Q53QU3_HUMAN def: "Septin" [UniProtKB:Q53QU3] xref: EMBL:AAY14718.1 xref: UniProtKB:Q53QU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006375 ! NEDD5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0023704 name: K1C16_HUMAN def: "Keratin, type I cytoskeletal 16" [UniProtKB:P08779] synonym: "CK-16" EXACT [UniProtKB:P08779] synonym: "Cytokeratin-16" EXACT [UniProtKB:P08779] synonym: "K16" EXACT [UniProtKB:P08779] synonym: "Keratin-16" EXACT [UniProtKB:P08779] xref: EMBL:AAA59460.1 xref: EMBL:AAB34564.1 xref: EMBL:AAB35421.1 xref: EMBL:AAC99326.1 xref: EMBL:AAD15829.1 xref: EMBL:AAH39169.1 xref: UniProtKB:P08779 xref: UniProtKB:P30654 xref: UniProtKB:Q16402 xref: UniProtKB:Q9UBG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012911 ! KRT16_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: participates_in CCO:I0016584 ! tank-krt16 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0023715 name: K1C10_HUMAN def: "Keratin, type I cytoskeletal 10" [UniProtKB:P13645] synonym: "CK-10" EXACT [UniProtKB:P13645] synonym: "Cytokeratin-10" EXACT [UniProtKB:P13645] synonym: "K10" EXACT [UniProtKB:P13645] synonym: "Keratin-10" EXACT [UniProtKB:P13645] xref: EMBL:AAA59199.1 xref: EMBL:AAA59468.1 xref: EMBL:AAA60544.1 xref: EMBL:AAB59438.1 xref: EMBL:AAB59439.1 xref: EMBL:AAH34697.1 xref: EMBL:CAA32649.1 xref: UniProtKB:P13645 xref: UniProtKB:Q14664 xref: UniProtKB:Q8N175 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0012908 ! KRT10_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004373 ! structural constituent of epidermis relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: participates_in CCO:I0008962 ! smad3-sry-3 physical interaction [Term] id: CCO:B0023749 name: K1C20_HUMAN def: "Keratin, type I cytoskeletal 20" [UniProtKB:P35900] synonym: "CK-20" EXACT [UniProtKB:P35900] synonym: "Cytokeratin-20" EXACT [UniProtKB:P35900] synonym: "K20" EXACT [UniProtKB:P35900] synonym: "Keratin-20" EXACT [UniProtKB:P35900] synonym: "Protein IT" EXACT [UniProtKB:P35900] xref: EMBL:AAH31559.1 xref: EMBL:CAA51913.1 xref: EMBL:CAA51914.1 xref: UniProtKB:P35900 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0012913 ! KRT20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015412 ! eif4el3-krt20 physical interaction relationship: transforms_into CCO:B0039927 ! K1C20_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0039928 ! K1C20_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0039929 ! K1C20_HUMAN-Phosphoserine34 [Term] id: CCO:B0023760 name: RBM11_HUMAN def: "Putative RNA-binding protein 11" [UniProtKB:P57052] synonym: "RNA-binding motif protein 11" EXACT [UniProtKB:P57052] xref: EMBL:AAH30196.2 xref: EMBL:AAL82535.1 xref: EMBL:AAM75350.1 xref: EMBL:BAA95545.1 xref: EMBL:BAC03638.1 xref: UniProtKB:P57052 xref: UniProtKB:Q6YNC2 xref: UniProtKB:Q8NBA1 xref: UniProtKB:Q8NFF6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008063 ! RBM11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015000 ! pepp2-rbm11 physical interaction [Term] id: CCO:B0023770 name: NOSTN_HUMAN def: "Nostrin" [UniProtKB:Q8IVI9] synonym: "BM247 homolog" EXACT [UniProtKB:Q8IVI9] synonym: "eNOS trafficking inducer" EXACT [UniProtKB:Q8IVI9] synonym: "Nitric oxide synthase traffic inducer" EXACT [UniProtKB:Q8IVI9] synonym: "Nitric oxide synthase trafficker" EXACT [UniProtKB:Q8IVI9] xref: EMBL:AAH14189.1 xref: EMBL:AAH93072.1 xref: EMBL:AAY24097.1 xref: EMBL:ABD62889.1 xref: EMBL:BAE46614.1 xref: EMBL:CAD58724.1 xref: UniProtKB:Q27HG3 xref: UniProtKB:Q53S62 xref: UniProtKB:Q8IVI9 xref: UniProtKB:Q96CJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018820 ! NOSTRIN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068796 ! NOSTN_HUMAN-Phosphothreonine174 relationship: transforms_into CCO:B0068797 ! NOSTN_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0068798 ! NOSTN_HUMAN-Phosphothreonine177 [Term] id: CCO:B0023793 name: FURIN_HUMAN def: "Furin precursor" [UniProtKB:P09958] synonym: "Dibasic-processing enzyme" EXACT [UniProtKB:P09958] synonym: "EC 3.4.21.75" EXACT [UniProtKB:P09958] synonym: "PACE" EXACT [UniProtKB:P09958] synonym: "Paired basic amino acid residue cleaving enzyme" EXACT [UniProtKB:P09958] xref: EMBL:AAH12181.1 xref: EMBL:CAA27860.1 xref: EMBL:CAA33745.1 xref: EMBL:CAA34948.1 xref: UniProtKB:P09958 xref: UniProtKB:Q14336 xref: UniProtKB:Q6LBS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017847 ! FURIN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001652 ! negative regulation of low-density lipoprotein receptor catabolic process relationship: participates_in CCO:P0001710 ! nerve growth factor production relationship: transforms_into CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: transforms_into CCO:B0066304 ! FURIN_HUMAN-Phosphoserine775 [Term] id: CCO:B0023795 name: PCSK6_HUMAN def: "Proprotein convertase subtilisin/kexin type 6 precursor" [UniProtKB:P29122] synonym: "EC 3.4.21.-" EXACT [UniProtKB:P29122] synonym: "Paired basic amino acid cleaving enzyme 4" EXACT [UniProtKB:P29122] synonym: "SPC4" EXACT [UniProtKB:P29122] synonym: "Subtilisin-like proprotein convertase 4" EXACT [UniProtKB:P29122] synonym: "Subtilisin/kexin-like protease PACE4" EXACT [UniProtKB:P29122] xref: EMBL:AAA59998.1 xref: EMBL:BAA05871.1 xref: EMBL:BAA05872.1 xref: EMBL:BAA21620.1 xref: EMBL:BAA21621.1 xref: EMBL:BAA21622.1 xref: EMBL:BAA21623.1 xref: EMBL:BAA21624.1 xref: EMBL:BAA21625.1 xref: EMBL:BAA21626.1 xref: EMBL:BAA21627.1 xref: EMBL:BAA21791.1 xref: EMBL:BAA21792.1 xref: EMBL:BAA21793.1 xref: UniProtKB:P29122 xref: UniProtKB:Q15099 xref: UniProtKB:Q15100 xref: UniProtKB:Q9UEG7 xref: UniProtKB:Q9UEJ1 xref: UniProtKB:Q9UEJ2 xref: UniProtKB:Q9UEJ7 xref: UniProtKB:Q9UEJ8 xref: UniProtKB:Q9UEJ9 xref: UniProtKB:Q9Y4G9 xref: UniProtKB:Q9Y4H0 xref: UniProtKB:Q9Y4H1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019324 ! PCSK6_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000715 ! subtilase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003378 ! proprotein convertase activity relationship: has_function CCO:F0005863 ! eukaryotic cell surface binding relationship: has_function CCO:F0007336 ! nerve growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000377 ! Golgi lumen relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001271 ! regulation of BMP signaling pathway relationship: participates_in CCO:P0001710 ! nerve growth factor production [Term] id: CCO:B0023825 name: HS71L_HUMAN def: "Heat shock 70 kDa protein 1L" [UniProtKB:P34931] synonym: "Heat shock 70 kDa protein 1-Hom" EXACT [UniProtKB:P34931] synonym: "Heat shock 70 kDa protein 1-like" EXACT [UniProtKB:P34931] synonym: "HSP70-Hom" EXACT [UniProtKB:P34931] xref: EMBL:AAA63228.1 xref: EMBL:AAD21817.1 xref: EMBL:AAH34483.1 xref: EMBL:ABC88476.1 xref: EMBL:BAA32521.1 xref: EMBL:BAB63301.1 xref: EMBL:CAI17736.1 xref: EMBL:CAI18215.1 xref: EMBL:CAI18463.1 xref: UniProtKB:A6NNB0 xref: UniProtKB:O75634 xref: UniProtKB:P34931 xref: UniProtKB:Q2HXR3 xref: UniProtKB:Q8NE72 xref: UniProtKB:Q96QC9 xref: UniProtKB:Q9UQM1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007631 ! HSPA1L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016348 ! rel-hspa1l physical interaction relationship: participates_in CCO:I0016369 ! nfkbia-hspa1l physical interaction relationship: participates_in CCO:I0016388 ! nfkbib-hspa1l physical interaction relationship: participates_in CCO:I0016448 ! ikbkb-hspa1l physical interaction relationship: participates_in CCO:I0016490 ! ikbkg-hspa1l physical interaction relationship: participates_in CCO:I0016570 ! tank-hspa1l physical interaction relationship: participates_in CCO:I0016592 ! map3k1-hspa1l physical interaction relationship: participates_in CCO:I0016664 ! map3k3-hspa1l physical interaction relationship: participates_in CCO:I0016775 ! nfkb2-hspa1l-1 physical interaction relationship: participates_in CCO:I0016853 ! relb-hspa1l physical interaction relationship: participates_in CCO:I0016892 ! ripk1-hspa1l physical interaction relationship: participates_in CCO:I0016906 ! ripk2-hspa1l physical interaction relationship: participates_in CCO:I0016921 ! map3k7ip1-hspa1l physical interaction relationship: participates_in CCO:I0016985 ! tnfrsf1a-hspa1l physical interaction relationship: participates_in CCO:I0017059 ! tradd-hspa1l physical interaction relationship: participates_in CCO:I0017088 ! traf1-hspa1l physical interaction relationship: participates_in CCO:I0017112 ! traf2-hspa1l physical interaction relationship: participates_in CCO:I0017134 ! traf6-hspa1l physical interaction [Term] id: CCO:B0023839 name: HSP76_HUMAN def: "Heat shock 70 kDa protein 6" [UniProtKB:P17066] synonym: "Heat shock 70 kDa protein B'" EXACT [UniProtKB:P17066] xref: EMBL:AAH04279.1 xref: EMBL:AAH35665.1 xref: EMBL:CAA36061.1 xref: EMBL:CAA36062.1 xref: UniProtKB:P17066 xref: UniProtKB:Q8IYK7 xref: UniProtKB:Q9BT95 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007634 ! HSPA6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016353 ! rel-hspa6 physical interaction relationship: participates_in CCO:I0016510 ! ikbkg-hspa6 physical interaction relationship: participates_in CCO:I0016605 ! map3k1-hspa6 physical interaction relationship: participates_in CCO:I0016688 ! map3k3-hspa6 physical interaction relationship: participates_in CCO:I0016863 ! relb-hspa6 physical interaction relationship: participates_in CCO:I0016908 ! ripk2-hspa6 physical interaction relationship: participates_in CCO:I0016926 ! map3k7ip1-hspa6 physical interaction relationship: participates_in CCO:I0016997 ! tnfrsf1a-hspa6 physical interaction [Term] id: CCO:B0023915 name: CAP1_HUMAN def: "Adenylyl cyclase-associated protein 1" [UniProtKB:Q01518] synonym: "CAP 1" EXACT [UniProtKB:Q01518] xref: EMBL:AAA35507.1 xref: EMBL:AAA35648.1 xref: EMBL:AAH13963.1 xref: EMBL:AAH95440.1 xref: EMBL:AAP35816.1 xref: EMBL:BAD96233.1 xref: EMBL:CAG33690.1 xref: EMBL:CAI11022.1 xref: UniProtKB:Q01518 xref: UniProtKB:Q53HR7 xref: UniProtKB:Q5T0S1 xref: UniProtKB:Q6I9U6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011268 ! CAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039334 ! CAP1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0039335 ! CAP1_HUMAN-Phosphotyrosine164 relationship: transforms_into CCO:B0039336 ! CAP1_HUMAN-Phosphothreonine307 relationship: transforms_into CCO:B0039337 ! CAP1_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0064059 ! CAP1_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0064060 ! CAP1_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0064061 ! CAP1_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0064062 ! CAP1_HUMAN-Phosphoserine308 [Term] id: CCO:B0023918 name: CAP2_HUMAN def: "Adenylyl cyclase-associated protein 2" [UniProtKB:P40123] synonym: "CAP 2" EXACT [UniProtKB:P40123] xref: EMBL:AAA20587.1 xref: EMBL:AAH08481.1 xref: EMBL:CAG33303.1 xref: UniProtKB:P40123 xref: UniProtKB:Q6IAY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011269 ! CAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039338 ! CAP2_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0039339 ! CAP2_HUMAN-Phosphoserine301 [Term] id: CCO:B0023930 name: BRM1L_HUMAN def: "Breast cancer metastasis-suppressor 1-like protein" [UniProtKB:Q5PSV4] synonym: "BRMS1-homolog protein p40" EXACT [UniProtKB:Q5PSV4] synonym: "BRMS1-like protein p40" EXACT [UniProtKB:Q5PSV4] xref: EMBL:AAH06250.2 xref: EMBL:AAV83797.1 xref: UniProtKB:A6NFW5 xref: UniProtKB:A6NH45 xref: UniProtKB:Q5PSV4 xref: UniProtKB:Q9BRI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007311 ! BRMS1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0023936 name: Q9BZ74_HUMAN def: "FKSG42" [UniProtKB:Q9BZ74] xref: EMBL:AAG50293.1 xref: UniProtKB:Q9BZ74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008947 ! FKSG42_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0023937 name: Q9H9L9_HUMAN def: "cDNA FLJ12664 fis, clone NT2RM4002226, weakly similar to GTPASE ACTIVATING PROTEIN ROTUND" [UniProtKB:Q9H9L9] xref: EMBL:BAB14206.1 xref: UniProtKB:Q9H9L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0023940 name: CCNL2_HUMAN def: "Cyclin-L2" [UniProtKB:Q96S94] synonym: "Paneth cell-enhanced expression protein" EXACT [UniProtKB:Q96S94] xref: EMBL:AAH16333.1 xref: EMBL:AAH71622.1 xref: EMBL:AAK67631.1 xref: EMBL:AAM76789.1 xref: EMBL:AAP97201.1 xref: EMBL:BAB84938.1 xref: EMBL:CAD39092.1 xref: EMBL:CAD39101.1 xref: EMBL:CAI22659.1 xref: EMBL:CAI22660.2 xref: UniProtKB:Q5T2N5 xref: UniProtKB:Q5T2N6 xref: UniProtKB:Q6IQ12 xref: UniProtKB:Q7Z4Z8 xref: UniProtKB:Q8N3C9 xref: UniProtKB:Q8N3D5 xref: UniProtKB:Q8NHE3 xref: UniProtKB:Q8TEL0 xref: UniProtKB:Q96B00 xref: UniProtKB:Q96S94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007358 ! CCNL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0034613 ! CCNL2_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0034614 ! CCNL2_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0034615 ! CCNL2_HUMAN-Phosphoserine369 [Term] id: CCO:B0023961 name: Q8NIA3_HUMAN def: "Alternate SOS1" [UniProtKB:Q8NIA3] xref: EMBL:AAM22406.1 xref: UniProtKB:Q8NIA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005649 ! SOS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0023973 name: TF2H3_HUMAN def: "General transcription factor IIH subunit 3" [UniProtKB:Q13889] synonym: "Basic transcription factor 2 34 kDa subunit" EXACT [UniProtKB:Q13889] synonym: "BTF2-p34" EXACT [UniProtKB:Q13889] synonym: "General transcription factor IIH polypeptide 3" EXACT [UniProtKB:Q13889] synonym: "TFIIH basal transcription factor complex p34 subunit" EXACT [UniProtKB:Q13889] xref: EMBL:AAH39726.1 xref: EMBL:AAH47868.2 xref: EMBL:AAH65250.1 xref: EMBL:AAN40702.1 xref: EMBL:CAA82909.1 xref: UniProtKB:Q13889 xref: UniProtKB:Q7L0G0 xref: UniProtKB:Q96AT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008283 ! GTF2H3_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000087 ! core TFIIH complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000279 ! holo TFIIH complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024005 name: UBP22_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 22" [UniProtKB:Q9UPT9] synonym: "Deubiquitinating enzyme 22" EXACT [UniProtKB:Q9UPT9] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q9UPT9] synonym: "Ubiquitin thioesterase 22" EXACT [UniProtKB:Q9UPT9] synonym: "Ubiquitin-specific-processing protease 22" EXACT [UniProtKB:Q9UPT9] xref: EMBL:BAA83015.1 xref: UniProtKB:Q9UPT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013411 ! USP22_human relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002509 ! H4 histone acetyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000012 ! SAGA complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008814 ! usp22-hexa physical interaction relationship: participates_in CCO:I0008815 ! usp22-mrpl10 physical interaction relationship: participates_in CCO:I0008816 ! usp22-psme1 physical interaction relationship: participates_in CCO:I0008817 ! usp22-scfd1 physical interaction relationship: participates_in CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0024022 name: PAK2_HUMAN def: "Serine/threonine-protein kinase PAK 2" [UniProtKB:Q13177] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13177] synonym: "Gamma-PAK" EXACT [UniProtKB:Q13177] synonym: "p21-activated kinase 2" EXACT [UniProtKB:Q13177] synonym: "p58" EXACT [UniProtKB:Q13177] synonym: "PAK-2" EXACT [UniProtKB:Q13177] synonym: "PAK65" EXACT [UniProtKB:Q13177] synonym: "S6/H4 kinase" EXACT [UniProtKB:Q13177] xref: EMBL:AAA65442.1 xref: EMBL:AAA75468.1 xref: EMBL:AAH69613.1 xref: UniProtKB:Q13154 xref: UniProtKB:Q13177 xref: UniProtKB:Q6ISC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007947 ! PAK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017274 ! pak2-pak2-3 phosphorylation relationship: participates_in CCO:I0017275 ! pak2-limk1-2 phosphorylation relationship: participates_in CCO:I0017276 ! pak2-raf1-2 phosphorylation relationship: participates_in CCO:I0018128 ! pak2-limk1-1 direct interaction relationship: participates_in CCO:I0018129 ! pak2-raf1-1 direct interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035335 ! PAK2_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0035336 ! PAK2_HUMAN-Phosphotyrosine139 relationship: transforms_into CCO:B0035337 ! PAK2_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0035338 ! PAK2_HUMAN-Phosphothreonine143 relationship: transforms_into CCO:B0035339 ! PAK2_HUMAN-Phosphothreonine402 relationship: transforms_into CCO:B0043337 ! PAK2_HUMAN-Phosphothreonine60 relationship: transforms_into CCO:B0069065 ! PAK2_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0069066 ! PAK2_HUMAN-Phosphothreonine169 [Term] id: CCO:B0024051 name: ADEC1_HUMAN def: "ADAM DEC1 precursor" [UniProtKB:O15204] synonym: "A disintegrin and metalloproteinase domain-like protein decysin 1" EXACT [UniProtKB:O15204] synonym: "ADAM-like protein decysin 1" EXACT [UniProtKB:O15204] synonym: "EC 3.4.24.-" EXACT [UniProtKB:O15204] xref: EMBL:AAH69582.1 xref: EMBL:AAH74877.1 xref: EMBL:AAH74878.1 xref: EMBL:CAA73764.2 xref: UniProtKB:O15204 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007219 ! ADAMDEC1_human relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0024096 name: Q9BXV5_HUMAN def: "PNAS-139" [UniProtKB:Q9BXV5] xref: EMBL:AAK07550.1 xref: UniProtKB:Q9BXV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0024099 name: ARPC2_HUMAN def: "Actin-related protein 2/3 complex subunit 2" [UniProtKB:O15144] synonym: "Arp2/3 complex 34 kDa subunit" EXACT [UniProtKB:O15144] synonym: "p34-ARC" EXACT [UniProtKB:O15144] xref: EMBL:AAB64190.1 xref: EMBL:AAC50874.1 xref: EMBL:AAF71122.1 xref: EMBL:AAH00590.1 xref: EMBL:AAP35544.1 xref: UniProtKB:O15144 xref: UniProtKB:Q92801 xref: UniProtKB:Q9P1D4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014634 ! ARPC2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000443 ! Arp2/3 protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0024107 name: HSPB8_HUMAN def: "Heat shock protein beta-8" [UniProtKB:Q9UJY1] synonym: "Alpha-crystallin C chain" EXACT [UniProtKB:Q9UJY1] synonym: "E2-induced gene 1 protein" EXACT [UniProtKB:Q9UJY1] synonym: "HspB8" EXACT [UniProtKB:Q9UJY1] synonym: "Protein kinase H11" EXACT [UniProtKB:Q9UJY1] synonym: "Small stress protein-like protein HSP22" EXACT [UniProtKB:Q9UJY1] xref: EMBL:AAD55359.1 xref: EMBL:AAF09481.1 xref: EMBL:AAF65562.1 xref: EMBL:AAG17230.1 xref: EMBL:AAH02673.1 xref: EMBL:AAP35522.1 xref: EMBL:CAB66870.1 xref: EMBL:CAG38484.1 xref: UniProtKB:Q6FIH3 xref: UniProtKB:Q9UJY1 xref: UniProtKB:Q9UKS3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007635 ! HSPB8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015656 ! bag3-hspb8-1 physical interaction relationship: participates_in CCO:I0018076 ! hspb7-hspb1-1 physical interaction relationship: participates_in CCO:I0018077 ! hspb7-hspb1-2 physical interaction relationship: participates_in CCO:I0018847 ! hspb8-cryab-1 physical interaction relationship: transforms_into CCO:B0034863 ! HSPB8_HUMAN-Phosphothreonine63 relationship: transforms_into CCO:B0066934 ! HSPB8_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0066935 ! HSPB8_HUMAN-Phosphotyrosine118 [Term] id: CCO:B0024129 name: LKHA4_HUMAN def: "Leukotriene A-4 hydrolase" [UniProtKB:P09960] synonym: "EC 3.3.2.6" EXACT [UniProtKB:P09960] synonym: "Leukotriene A(4) hydrolase" EXACT [UniProtKB:P09960] synonym: "LTA-4 hydrolase" EXACT [UniProtKB:P09960] xref: EMBL:AAA36176.1 xref: EMBL:AAA36177.1 xref: EMBL:AAA89077.1 xref: EMBL:AAH32528.1 xref: UniProtKB:P09960 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007783 ! LTA4H_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000648 ! membrane alanyl aminopeptidase activity relationship: has_function CCO:F0000723 ! epoxide hydrolase activity relationship: has_function CCO:F0000863 ! leukotriene-A4 hydrolase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020511 ! arpc3-lta4h physical interaction [Term] id: CCO:B0024182 name: RPIA_HUMAN def: "Ribose-5-phosphate isomerase" [UniProtKB:P49247] synonym: "EC 5.3.1.6" EXACT [UniProtKB:P49247] synonym: "Phosphoriboisomerase" EXACT [UniProtKB:P49247] xref: EMBL:AAH15529.2 xref: EMBL:AAK95569.1 xref: UniProtKB:P49247 xref: UniProtKB:Q541P9 xref: UniProtKB:Q96BJ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011664 ! RPIA_human relationship: has_function CCO:F0001116 ! ribose-5-phosphate isomerase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015313 ! nif3l1-rpia physical interaction [Term] id: CCO:B0024266 name: POGZ_HUMAN def: "Pogo transposable element with ZNF domain" [UniProtKB:Q7Z3K3] xref: EMBL:AAH57773.1 xref: EMBL:BAA32306.1 xref: EMBL:BAB87117.1 xref: EMBL:BAE45744.1 xref: EMBL:CAB45136.1 xref: EMBL:CAD97850.1 xref: EMBL:CAI16807.1 xref: EMBL:CAI16808.2 xref: EMBL:CAI16809.1 xref: EMBL:CAI16810.1 xref: EMBL:EAW53440.1 xref: UniProtKB:O75049 xref: UniProtKB:Q3LIC4 xref: UniProtKB:Q5SZS1 xref: UniProtKB:Q5SZS2 xref: UniProtKB:Q5SZS3 xref: UniProtKB:Q5SZS4 xref: UniProtKB:Q7Z3K3 xref: UniProtKB:Q8TDZ7 xref: UniProtKB:Q9Y4X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019467 ! POGZ_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069435 ! POGZ_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0069436 ! POGZ_HUMAN-Phosphoserine419 relationship: transforms_into CCO:B0069437 ! POGZ_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0069438 ! POGZ_HUMAN-Phosphoserine1338 relationship: transforms_into CCO:B0069439 ! POGZ_HUMAN-Phosphoserine1364 [Term] id: CCO:B0024299 name: IPO11_HUMAN def: "Importin-11" [UniProtKB:Q9UI26] synonym: "Imp11" EXACT [UniProtKB:Q9UI26] synonym: "Ran-binding protein 11" EXACT [UniProtKB:Q9UI26] synonym: "RanBP11" EXACT [UniProtKB:Q9UI26] xref: EMBL:AAF21936.1 xref: EMBL:AAH31694.1 xref: EMBL:AAH33776.1 xref: EMBL:BAA91843.1 xref: EMBL:CAB82416.1 xref: EMBL:EAW51379.1 xref: UniProtKB:A6NGJ5 xref: UniProtKB:Q8N5R2 xref: UniProtKB:Q9NSJ6 xref: UniProtKB:Q9NVB1 xref: UniProtKB:Q9UI26 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007676 ! IPO11_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015440 ! ipo11-traf2 physical interaction relationship: participates_in CCO:I0015621 ! ipo11-plcd4 physical interaction [Term] id: CCO:B0024303 name: Q4VBB4_HUMAN def: "Orphan GPCR 68" [UniProtKB:Q4VBB4] synonym: "G protein-coupled receptor 68" EXACT [UniProtKB:Q4VBB4] synonym: "G protein-coupled receptor 68, isoform CRA_a" EXACT [UniProtKB:Q4VBB4] xref: EMBL:AAH96071.1 xref: EMBL:AAH96072.1 xref: EMBL:AAH96073.1 xref: EMBL:AAH96074.1 xref: EMBL:AAH98567.1 xref: EMBL:ACG60649.1 xref: EMBL:EAW81447.1 xref: UniProtKB:Q4VBB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021121 ! GPR68_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0024306 name: PSYR_HUMAN def: "Psychosine receptor" [UniProtKB:Q8IYL9] synonym: "G-protein coupled receptor 65" EXACT [UniProtKB:Q8IYL9] synonym: "T-cell death-associated protein 8" EXACT [UniProtKB:Q8IYL9] xref: EMBL:AAC31794.1 xref: EMBL:AAH35633.1 xref: EMBL:AAH71715.1 xref: UniProtKB:O75819 xref: UniProtKB:Q8IYL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019535 ! GPR65_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0069586 ! PSYR_HUMAN-Phosphotyrosine113 [Term] id: CCO:B0024308 name: GPR4_HUMAN def: "Probable G-protein coupled receptor 4" [UniProtKB:P46093] synonym: "G-protein coupled receptor 19" EXACT [UniProtKB:P46093] xref: EMBL:AAA63180.1 xref: EMBL:AAA79061.1 xref: EMBL:AAA98457.1 xref: EMBL:AAH67536.1 xref: UniProtKB:P46093 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018023 ! GPR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0024312 name: DLL3_HUMAN def: "Delta-like protein 3 precursor" [UniProtKB:Q9NYJ7] synonym: "Delta3" EXACT [UniProtKB:Q9NYJ7] synonym: "Drosophila Delta homolog 3" EXACT [UniProtKB:Q9NYJ7] xref: EMBL:AAF62542.1 xref: EMBL:AAH00218.1 xref: UniProtKB:Q9NYJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017583 ! DLL3_human relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0024344 name: Q9UG28_HUMAN def: "Putative uncharacterized protein DKFZp434G222" [UniProtKB:Q9UG28] xref: EMBL:CAB45775.2 xref: UniProtKB:Q9UG28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006377 ! DKFZp434G222_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024369 name: IL7_HUMAN def: "Interleukin-7 precursor" [UniProtKB:P13232] synonym: "IL-7" EXACT [UniProtKB:P13232] xref: EMBL:AAA59156.1 xref: EMBL:AAC63047.1 xref: EMBL:AAH47698.1 xref: UniProtKB:P13232 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007672 ! IL7_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001441 ! interleukin-7 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0016221 ! il7-il7r-3 physical interaction relationship: participates_in CCO:I0017309 ! il7-il2rg-1 physical interaction relationship: participates_in CCO:I0017385 ! il7-il7r-2 physical interaction relationship: participates_in CCO:I0017518 ! il7-il7r-1 physical interaction relationship: participates_in CCO:I0017519 ! il7-il2rg-2 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002396 ! positive regulation of T cell differentiation [Term] id: CCO:B0024383 name: PUM2_HUMAN def: "Pumilio homolog 2" [UniProtKB:Q8TB72] synonym: "Pumilio-2" EXACT [UniProtKB:Q8TB72] xref: EMBL:AAG31806.1 xref: EMBL:AAH24218.2 xref: EMBL:AAI12047.1 xref: EMBL:AAI12049.1 xref: EMBL:AAL36981.1 xref: EMBL:AAY15026.1 xref: EMBL:BAA19665.3 xref: UniProtKB:O00234 xref: UniProtKB:Q53TV7 xref: UniProtKB:Q8TB72 xref: UniProtKB:Q8WY43 xref: UniProtKB:Q9HAN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019559 ! PUM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017296 ! crsp3-pum2 physical interaction relationship: participates_in CCO:I0017767 ! pum2-dazl1-4 physical interaction relationship: participates_in CCO:I0017768 ! dazl1-pum2-4 physical interaction relationship: participates_in CCO:I0018391 ! daz1-pum2-1 physical interaction relationship: participates_in CCO:I0018392 ! daz1-pum2-3 physical interaction relationship: participates_in CCO:I0018702 ! pum2-daz1-1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0069628 ! PUM2_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0069629 ! PUM2_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0069630 ! PUM2_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0069631 ! PUM2_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0069632 ! PUM2_HUMAN-Phosphothreonine184 relationship: transforms_into CCO:B0069633 ! PUM2_HUMAN-Phosphoserine587 [Term] id: CCO:B0024392 name: PUM1_HUMAN def: "Pumilio homolog 1" [UniProtKB:Q14671] synonym: "HsPUM" EXACT [UniProtKB:Q14671] synonym: "Pumilio-1" EXACT [UniProtKB:Q14671] xref: EMBL:AAG31807.1 xref: EMBL:AAH13398.1 xref: EMBL:BAA07895.3 xref: EMBL:CAH71203.1 xref: EMBL:CAI22246.1 xref: UniProtKB:Q14671 xref: UniProtKB:Q5VXY7 xref: UniProtKB:Q9HAN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019558 ! PUM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019004 ! atxn1-pum1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0069623 ! PUM1_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0069624 ! PUM1_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0069625 ! PUM1_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0069626 ! PUM1_HUMAN-Phosphoserine709 relationship: transforms_into CCO:B0069627 ! PUM1_HUMAN-Phosphoserine714 [Term] id: CCO:B0024398 name: RAP2B_HUMAN def: "Ras-related protein Rap-2b precursor" [UniProtKB:P61225] xref: EMBL:AAH12362.1 xref: EMBL:AAM12629.1 xref: EMBL:CAA37178.1 xref: UniProtKB:P17964 xref: UniProtKB:P61225 xref: UniProtKB:Q96EG5 xref: UniProtKB:Q9CXG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008055 ! RAP2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035511 ! RAP2B_HUMAN-Cysteine methyl ester180 [Term] id: CCO:B0024399 name: Q5U0C3_HUMAN def: "RAP1A, member of RAS oncogene family" [UniProtKB:Q5U0C3] xref: EMBL:AAV38472.1 xref: UniProtKB:Q5U0C3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0024403 name: A6NNR4_HUMAN def: "Uncharacterized protein ENSP00000344361" [UniProtKB:A6NNR4] xref: UniProtKB:A6NNR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0024404 name: RAP2A_HUMAN def: "Ras-related protein Rap-2a precursor" [UniProtKB:P10114] synonym: "RbBP-30" EXACT [UniProtKB:P10114] xref: EMBL:AAH41333.1 xref: EMBL:AAH70031.1 xref: EMBL:AAM12628.1 xref: EMBL:AAN71845.1 xref: EMBL:CAA31052.1 xref: EMBL:CAI39499.1 xref: UniProtKB:P10114 xref: UniProtKB:Q5JSC1 xref: UniProtKB:Q5JSC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008054 ! RAP2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019380 ! pfta-rap2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035510 ! RAP2A_HUMAN-Cysteine methyl ester180 [Term] id: CCO:B0024407 name: RAP2C_HUMAN def: "Ras-related protein Rap-2c precursor" [UniProtKB:Q9Y3L5] xref: EMBL:AAH03403.1 xref: EMBL:AAP55684.1 xref: EMBL:CAB41256.1 xref: EMBL:CAI42719.1 xref: UniProtKB:Q5H9H9 xref: UniProtKB:Q9BTS0 xref: UniProtKB:Q9Y3L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008056 ! RAP2C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035512 ! RAP2C_HUMAN-Cysteine methyl ester180 [Term] id: CCO:B0024408 name: Q9BXV4_HUMAN def: "PNAS-140" [UniProtKB:Q9BXV4] xref: EMBL:AAK07551.1 xref: UniProtKB:Q9BXV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0024410 name: RAP1B_HUMAN def: "Ras-related protein Rap-1b precursor" [UniProtKB:P61224] synonym: "GTP-binding protein smg p21B" EXACT [UniProtKB:P61224] xref: EMBL:AAH00176.1 xref: EMBL:AAH78173.1 xref: EMBL:AAH95467.1 xref: EMBL:AAM12627.1 xref: EMBL:AAV38896.1 xref: EMBL:ABQ52130.1 xref: EMBL:BAB93460.1 xref: EMBL:CAB45777.1 xref: EMBL:CAB46488.1 xref: EMBL:CAG28617.1 xref: EMBL:EAW97189.1 xref: UniProtKB:P09526 xref: UniProtKB:P61224 xref: UniProtKB:Q502X3 xref: UniProtKB:Q5TZR4 xref: UniProtKB:Q6DCA1 xref: UniProtKB:Q6LES0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008053 ! RAP1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016847 ! map3k14-rap1b physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035507 ! RAP1B_HUMAN-ADP-ribosylserine39 relationship: transforms_into CCO:B0035508 ! RAP1B_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0035509 ! RAP1B_HUMAN-Cysteine methyl ester181 [Term] id: CCO:B0024423 name: Q59EG3_HUMAN def: "MutL protein homolog 1 variant" [UniProtKB:Q59EG3] xref: EMBL:BAD93085.1 xref: UniProtKB:Q59EG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024426 name: Q53GX1_HUMAN def: "MutL protein homolog 1 variant" [UniProtKB:Q53GX1] xref: EMBL:BAD96530.1 xref: UniProtKB:Q53GX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024428 name: Q0ZAJ5_HUMAN def: "MLH1-Ex(9-10) isoform" [UniProtKB:Q0ZAJ5] xref: EMBL:ABG49486.1 xref: UniProtKB:Q0ZAJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005100 ! MLH1_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024472 name: BNC1_HUMAN def: "Zinc finger protein basonuclin-1" [UniProtKB:Q01954] xref: EMBL:AAA35584.1 xref: EMBL:AAB53028.1 xref: UniProtKB:Q01954 xref: UniProtKB:Q15840 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017169 ! BNC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0063945 ! BNC1_HUMAN-Phosphoserine537 relationship: transforms_into CCO:B0063946 ! BNC1_HUMAN-Phosphoserine541 [Term] id: CCO:B0024477 name: BNC2_HUMAN def: "Zinc finger protein basonuclin-2" [UniProtKB:Q6ZN30] xref: EMBL:AAR99389.1 xref: EMBL:BAA90908.1 xref: EMBL:BAB15269.1 xref: EMBL:BAC03837.1 xref: EMBL:BAD18545.1 xref: EMBL:CAM21221.1 xref: UniProtKB:B1APG9 xref: UniProtKB:Q6T3A3 xref: UniProtKB:Q6ZN30 xref: UniProtKB:Q8NAR2 xref: UniProtKB:Q9H6J0 xref: UniProtKB:Q9NXV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017170 ! BNC2_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024481 name: Q6ZNQ9_HUMAN def: "cDNA FLJ27321 fis, clone TMS07849, highly similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11)" [UniProtKB:Q6ZNQ9] xref: EMBL:BAC85441.1 xref: UniProtKB:Q6ZNQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0024484 name: PLCB3_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3" [UniProtKB:Q01970] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q01970] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:Q01970] synonym: "Phospholipase C-beta-3" EXACT [UniProtKB:Q01970] synonym: "PLC-beta-3" EXACT [UniProtKB:Q01970] xref: EMBL:AAA77683.1 xref: EMBL:CAA78903.1 xref: EMBL:CAA85776.1 xref: UniProtKB:Q01970 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019428 ! PLCB3_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069384 ! PLCB3_HUMAN-Phosphoserine537 relationship: transforms_into CCO:B0069385 ! PLCB3_HUMAN-Phosphoserine926 relationship: transforms_into CCO:B0069386 ! PLCB3_HUMAN-Phosphoserine931 relationship: transforms_into CCO:B0069387 ! PLCB3_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0069388 ! PLCB3_HUMAN-Phosphothreonine1122 [Term] id: CCO:B0024486 name: Q8N1A4_HUMAN def: "Similar to phospholipase C, beta 3 (Phosphatidylinositol-specific)" [UniProtKB:Q8N1A4] xref: EMBL:AAH32659.1 xref: UniProtKB:Q8N1A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0024487 name: PLCB2_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2" [UniProtKB:Q00722] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q00722] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:Q00722] synonym: "Phospholipase C-beta-2" EXACT [UniProtKB:Q00722] synonym: "PLC-beta-2" EXACT [UniProtKB:Q00722] xref: EMBL:AAA36453.1 xref: EMBL:BAF84346.1 xref: UniProtKB:A8K6J2 xref: UniProtKB:Q00722 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022518 ! PLCB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction [Term] id: CCO:B0024549 name: Q4LE28_HUMAN def: "CREBBP variant protein" [UniProtKB:Q4LE28] xref: EMBL:BAE06125.1 xref: UniProtKB:Q4LE28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014259 ! CREBBP variant protein_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000011 ! histone acetyltransferase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0024552 name: O60424_HUMAN def: "CBP" [UniProtKB:O60424] xref: EMBL:AAC17736.1 xref: UniProtKB:O60424 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021069 ! CBP_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000011 ! histone acetyltransferase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0024568 name: MOL1B_HUMAN def: "Mps one binder kinase activator-like 1B" [UniProtKB:Q9H8S9] synonym: "Mob1 alpha" EXACT [UniProtKB:Q9H8S9] synonym: "Mob1 homolog 1B" EXACT [UniProtKB:Q9H8S9] synonym: "Mob1A" EXACT [UniProtKB:Q9H8S9] synonym: "Protein Mob4B" EXACT [UniProtKB:Q9H8S9] xref: EMBL:AAH03398.1 xref: EMBL:AAX93060.1 xref: EMBL:BAA91810.1 xref: EMBL:BAB13868.1 xref: EMBL:BAB14525.1 xref: EMBL:BAB19058.1 xref: EMBL:CAE12093.1 xref: UniProtKB:Q53S34 xref: UniProtKB:Q9H3T5 xref: UniProtKB:Q9H8S9 xref: UniProtKB:Q9HAI0 xref: UniProtKB:Q9NVE2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007831 ! MOBKL1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017935 ! stk38-mobk1b-1 physical interaction relationship: participates_in CCO:I0017936 ! mobk1b-stk38-1 physical interaction relationship: participates_in CCO:I0018097 ! stk38l-mobk1b-1 physical interaction relationship: transforms_into CCO:B0035205 ! MOL1B_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0035206 ! MOL1B_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0035207 ! MOL1B_HUMAN-Phosphothreonine35 relationship: transforms_into CCO:B0035208 ! MOL1B_HUMAN-Phosphoserine38 [Term] id: CCO:B0024576 name: TBA3C_HUMAN def: "Tubulin alpha-3C/D chain" [UniProtKB:Q13748] synonym: "Alpha-tubulin 2" EXACT [UniProtKB:Q13748] synonym: "Alpha-tubulin 3C/D" EXACT [UniProtKB:Q13748] synonym: "Tubulin alpha-2 chain" EXACT [UniProtKB:Q13748] xref: EMBL:AAA35521.1 xref: EMBL:AAC39578.1 xref: EMBL:AAH11721.1 xref: EMBL:AAH57810.1 xref: EMBL:CAH73534.1 xref: EMBL:EAX08210.1 xref: UniProtKB:A6NJQ0 xref: UniProtKB:Q13748 xref: UniProtKB:Q5W099 xref: UniProtKB:Q6PEY3 xref: UniProtKB:Q96F18 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008267 ! TUBA3C_human relationship: encoded_by CCO:G0008268 ! TUBA3D_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0015818 ! nmi-tuba2 physical interaction relationship: participates_in CCO:I0016368 ! rel-tuba2 physical interaction relationship: participates_in CCO:I0016384 ! nfkbia-tuba2 physical interaction relationship: participates_in CCO:I0016420 ! nfkbib-tuba2 physical interaction relationship: participates_in CCO:I0016444 ! chuk-tuba2 physical interaction relationship: participates_in CCO:I0016465 ! ikbkb-tuba2 physical interaction relationship: participates_in CCO:I0016485 ! ikbke-tuba2 physical interaction relationship: participates_in CCO:I0016560 ! ikbkg-tuba2 physical interaction relationship: participates_in CCO:I0016585 ! tank-tuba2 physical interaction relationship: participates_in CCO:I0016648 ! map3k1-tuba2 physical interaction relationship: participates_in CCO:I0016753 ! map3k3-tuba2 physical interaction relationship: participates_in CCO:I0016828 ! nfkb2-tuba2-1 physical interaction relationship: participates_in CCO:I0016886 ! relb-tuba2 physical interaction relationship: participates_in CCO:I0016905 ! ripk1-tuba2 physical interaction relationship: participates_in CCO:I0016919 ! ripk2-tuba2 physical interaction relationship: participates_in CCO:I0016933 ! map3k7ip1-tuba2 physical interaction relationship: participates_in CCO:I0016956 ! q9nyj8-tuba2 physical interaction relationship: participates_in CCO:I0016979 ! tbk1-tuba2 physical interaction relationship: participates_in CCO:I0017032 ! tnfrsf1a-tuba2 physical interaction relationship: participates_in CCO:I0017083 ! tradd-tuba2 physical interaction relationship: participates_in CCO:I0017110 ! traf1-tuba2 physical interaction relationship: participates_in CCO:I0017131 ! traf2-tuba2 physical interaction relationship: participates_in CCO:I0017152 ! traf6-tuba2 physical interaction relationship: participates_in CCO:I0019416 ! tuba2-nmi physical interaction relationship: transforms_into CCO:B0035753 ! TBA3C_HUMAN-Phosphoserine48 [Term] id: CCO:B0024578 name: TBA8_HUMAN def: "Tubulin alpha-8 chain" [UniProtKB:Q9NY65] synonym: "Alpha-tubulin 8" EXACT [UniProtKB:Q9NY65] synonym: "Tubulin alpha chain-like 2" EXACT [UniProtKB:Q9NY65] xref: EMBL:AAH74827.1 xref: EMBL:AAI04846.1 xref: EMBL:CAB88036.1 xref: EMBL:CAG30486.1 xref: UniProtKB:Q2M3N4 xref: UniProtKB:Q9NY65 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008270 ! TUBA8_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0016551 ! ikbkg-tuba8 physical interaction relationship: transforms_into CCO:B0035755 ! TBA8_HUMAN-Phosphotyrosine103 relationship: transforms_into CCO:B0035756 ! TBA8_HUMAN-Phosphotyrosine357 [Term] id: CCO:B0024588 name: TBA1B_HUMAN def: "Tubulin alpha-1B chain" [UniProtKB:P68363] synonym: "Alpha-tubulin ubiquitous" EXACT [UniProtKB:P68363] synonym: "Tubulin alpha-ubiquitous chain" EXACT [UniProtKB:P68363] synonym: "Tubulin K-alpha-1" EXACT [UniProtKB:P68363] xref: EMBL:AAA91576.1 xref: EMBL:AAC31959.1 xref: EMBL:AAH00696.1 xref: EMBL:AAH01128.1 xref: EMBL:AAH06379.1 xref: EMBL:AAH06481.1 xref: EMBL:AAH08659.1 xref: EMBL:AAH09314.1 xref: EMBL:AAH09509.1 xref: EMBL:AAH09512.1 xref: EMBL:AAH09513.1 xref: EMBL:AAH10494.1 xref: EMBL:AAH11572.1 xref: EMBL:AAH15883.1 xref: EMBL:AAH17004.1 xref: EMBL:AAH30820.1 xref: EMBL:AAH71904.1 xref: EMBL:ABD60581.1 xref: UniProtKB:P04687 xref: UniProtKB:P05209 xref: UniProtKB:P68363 xref: UniProtKB:Q27I68 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005731 ! TUBA1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0014311 ! TBA1B_HUMAN-Phosphotyrosine272 [Term] id: CCO:B0024595 name: Q2M2Z8_HUMAN def: "CENTD1 protein" [UniProtKB:Q2M2Z8] xref: EMBL:AAI05090.1 xref: EMBL:AAI05092.1 xref: UniProtKB:Q2M2Z8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007382 ! CENTD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0024597 name: CEND3_HUMAN def: "Centaurin-delta-3" [UniProtKB:Q8WWN8] synonym: "Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3" EXACT [UniProtKB:Q8WWN8] synonym: "Cnt-d3" EXACT [UniProtKB:Q8WWN8] xref: EMBL:CAC83946.1 xref: UniProtKB:Q8WWN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017330 ! CENTD3_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001670 ! phosphatidylinositol-3,4,5-triphosphate binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004517 ! Rac GTPase activator activity relationship: has_function CCO:F0005836 ! phosphatidylinositol-3,4-bisphosphate binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: participates_in CCO:P0001983 ! negative regulation of Rac protein signal transduction relationship: participates_in CCO:P0001986 ! negative regulation of Rho protein signal transduction relationship: transforms_into CCO:B0064261 ! CEND3_HUMAN-Phosphotyrosine1403 relationship: transforms_into CCO:B0064262 ! CEND3_HUMAN-Phosphotyrosine1408 relationship: transforms_into CCO:B0064263 ! CEND3_HUMAN-Phosphoserine1444 [Term] id: CCO:B0024599 name: Q6ZMJ9_HUMAN def: "FLJ00357 protein" [UniProtKB:Q6ZMJ9] xref: EMBL:BAD18726.1 xref: UniProtKB:Q6ZMJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008808 ! FLJ00357_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0024600 name: CEND1_HUMAN def: "Centaurin-delta-1" [UniProtKB:Q8WZ64] synonym: "Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2" EXACT [UniProtKB:Q8WZ64] synonym: "Cnt-d1" EXACT [UniProtKB:Q8WZ64] synonym: "PARX protein" EXACT [UniProtKB:Q8WZ64] xref: EMBL:AAL04166.1 xref: EMBL:AAL12170.1 xref: EMBL:AAL32459.1 xref: EMBL:AAY40927.1 xref: EMBL:BAA25506.2 xref: UniProtKB:Q4W5D2 xref: UniProtKB:Q7Z2L5 xref: UniProtKB:Q8WZ64 xref: UniProtKB:Q96L70 xref: UniProtKB:Q96P49 xref: UniProtKB:Q9Y4E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007382 ! CENTD1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001670 ! phosphatidylinositol-3,4,5-triphosphate binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0034650 ! CEND1_HUMAN-Phosphotyrosine77 relationship: transforms_into CCO:B0034651 ! CEND1_HUMAN-Phosphotyrosine473 relationship: transforms_into CCO:B0034652 ! CEND1_HUMAN-Phosphoserine1600 [Term] id: CCO:B0024617 name: MMP2_HUMAN def: "72 kDa type IV collagenase precursor" [UniProtKB:P08253] synonym: "72 kDa gelatinase" EXACT [UniProtKB:P08253] synonym: "EC 3.4.24.24" EXACT [UniProtKB:P08253] synonym: "Gelatinase A" EXACT [UniProtKB:P08253] synonym: "Matrix metalloproteinase-2" EXACT [UniProtKB:P08253] synonym: "MMP-2" EXACT [UniProtKB:P08253] synonym: "TBE-1" EXACT [UniProtKB:P08253] xref: EMBL:AAA35701.1 xref: EMBL:AAA52027.1 xref: EMBL:AAA52028.1 xref: EMBL:AAH02576.1 xref: EMBL:AAU10089.1 xref: UniProtKB:P08253 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022401 ! MMP2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0000678 ! gelatinase A activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000933 ! sarcomere relationship: participates_in CCO:I0017800 ! hsp90aa1-mmp2 physical interaction relationship: participates_in CCO:I0019477 ! mmp2-timp2-1 direct interaction [Term] id: CCO:B0024681 name: WDR68_HUMAN def: "WD repeat-containing protein 68" [UniProtKB:P61962] synonym: "WD repeat-containing protein An11 homolog" EXACT [UniProtKB:P61962] xref: EMBL:AAC18913.1 xref: EMBL:AAH01264.1 xref: UniProtKB:O15491 xref: UniProtKB:P61962 xref: UniProtKB:Q9DAE4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022784 ! WDR68_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017226 ! map3k1-han11 physical interaction [Term] id: CCO:B0024694 name: BIG1_HUMAN def: "Brefeldin A-inhibited guanine nucleotide-exchange protein 1" [UniProtKB:Q9Y6D6] synonym: "Brefeldin A-inhibited GEP 1" EXACT [UniProtKB:Q9Y6D6] synonym: "p200 ARF guanine nucleotide exchange factor" EXACT [UniProtKB:Q9Y6D6] synonym: "p200 ARF-GEP1" EXACT [UniProtKB:Q9Y6D6] xref: EMBL:AAD38427.1 xref: EMBL:AAD43651.1 xref: EMBL:BAA91912.1 xref: EMBL:CAB55931.1 xref: UniProtKB:Q9NV46 xref: UniProtKB:Q9UFV2 xref: UniProtKB:Q9UNL0 xref: UniProtKB:Q9Y6D6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017154 ! ARFGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0003516 ! myosin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0063911 ! BIG1_HUMAN-Phosphoserine1569 [Term] id: CCO:B0024696 name: BIG2_HUMAN def: "Brefeldin A-inhibited guanine nucleotide-exchange protein 2" [UniProtKB:Q9Y6D5] synonym: "Brefeldin A-inhibited GEP 2" EXACT [UniProtKB:Q9Y6D5] xref: EMBL:AAD38428.1 xref: EMBL:CAI19320.1 xref: EMBL:CAI19614.1 xref: UniProtKB:Q5TFT9 xref: UniProtKB:Q9NTS1 xref: UniProtKB:Q9Y6D5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017155 ! ARFGEF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0063912 ! BIG2_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0063913 ! BIG2_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0063914 ! BIG2_HUMAN-Phosphoserine614 relationship: transforms_into CCO:B0063915 ! BIG2_HUMAN-Phosphothreonine616 relationship: transforms_into CCO:B0063916 ! BIG2_HUMAN-Phosphoserine690 relationship: transforms_into CCO:B0063917 ! BIG2_HUMAN-Phosphothreonine691 relationship: transforms_into CCO:B0063918 ! BIG2_HUMAN-Phosphoserine1511 relationship: transforms_into CCO:B0063919 ! BIG2_HUMAN-Phosphoserine1513 relationship: transforms_into CCO:B0063920 ! BIG2_HUMAN-Phosphoserine1514 relationship: transforms_into CCO:B0063921 ! BIG2_HUMAN-Phosphoserine1525 relationship: transforms_into CCO:B0063922 ! BIG2_HUMAN-Phosphoserine1528 [Term] id: CCO:B0024704 name: PPA6_HUMAN def: "Lysophosphatidic acid phosphatase type 6 precursor" [UniProtKB:Q9NPH0] synonym: "Acid phosphatase 6, lysophosphatidic" EXACT [UniProtKB:Q9NPH0] synonym: "Acid phosphatase-like protein 1" EXACT [UniProtKB:Q9NPH0] synonym: "EC 3.1.3.2" EXACT [UniProtKB:Q9NPH0] synonym: "PACPL1" EXACT [UniProtKB:Q9NPH0] xref: EMBL:AAH09965.1 xref: EMBL:AAH34686.1 xref: EMBL:AAQ88916.1 xref: EMBL:BAA89311.1 xref: EMBL:BAA91310.1 xref: EMBL:BAA94309.2 xref: EMBL:BAD92485.1 xref: EMBL:CAG33382.1 xref: EMBL:CAI15199.1 xref: UniProtKB:Q59G61 xref: UniProtKB:Q5T490 xref: UniProtKB:Q6IAQ3 xref: UniProtKB:Q7LG81 xref: UniProtKB:Q9NPH0 xref: UniProtKB:Q9UIG6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022524 ! ACP6_human relationship: has_function CCO:F0000478 ! acid phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0020220 ! acp6-gng7 physical interaction [Term] id: CCO:B0024762 name: POLK_HUMAN def: "DNA polymerase kappa" [UniProtKB:Q9UBT6] synonym: "DINB protein" EXACT [UniProtKB:Q9UBT6] synonym: "DINP" EXACT [UniProtKB:Q9UBT6] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9UBT6] xref: EMBL:AAF02540.1 xref: EMBL:AAF23270.1 xref: EMBL:AAH14955.1 xref: EMBL:AAH50718.1 xref: EMBL:AAN15780.1 xref: EMBL:AAN15781.1 xref: EMBL:AAP12648.1 xref: EMBL:BAA86943.1 xref: EMBL:BAB58975.1 xref: EMBL:BAB58976.1 xref: EMBL:BAC03714.1 xref: UniProtKB:Q86VJ8 xref: UniProtKB:Q8IZY0 xref: UniProtKB:Q8IZY1 xref: UniProtKB:Q8NB30 xref: UniProtKB:Q96L01 xref: UniProtKB:Q96Q86 xref: UniProtKB:Q96Q87 xref: UniProtKB:Q9UBT6 xref: UniProtKB:Q9UHC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007992 ! POLK_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0039595 ! POLK_HUMAN-Phosphothreonine372 [Term] id: CCO:B0024778 name: TNPO2_HUMAN def: "Transportin-2" [UniProtKB:O14787] synonym: "Karyopherin beta-2b" EXACT [UniProtKB:O14787] xref: EMBL:AAB71349.1 xref: EMBL:AAB83973.1 xref: UniProtKB:O14655 xref: UniProtKB:O14787 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008314 ! TNPO2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001742 ! nuclear localization sequence binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020679 ! tnpo2-pik3cd physical interaction [Term] id: CCO:B0024782 name: TOP1M_HUMAN def: "DNA topoisomerase I, mitochondrial precursor" [UniProtKB:Q969P6] synonym: "EC 5.99.1.2" EXACT [UniProtKB:Q969P6] synonym: "TOP1mt" EXACT [UniProtKB:Q969P6] xref: EMBL:AAL05624.1 xref: EMBL:AAL10791.1 xref: UniProtKB:Q969P6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008315 ! TOP1MT_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000419 ! DNA topoisomerase activity relationship: has_function CCO:F0000420 ! DNA topoisomerase type I activity relationship: has_function CCO:F0000421 ! DNA topoisomerase (ATP-hydrolyzing) activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000632 ! DNA unwinding during replication [Term] id: CCO:B0024794 name: ZIC3_HUMAN def: "Zinc finger protein ZIC 3" [UniProtKB:O60481] synonym: "Zinc finger protein of the cerebellum 3" EXACT [UniProtKB:O60481] xref: EMBL:AAC05594.1 xref: EMBL:AAI13394.1 xref: EMBL:AAI13396.1 xref: EMBL:CAB41648.1 xref: UniProtKB:O60481 xref: UniProtKB:Q14DE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020605 ! ZIC3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024799 name: ZIC1_HUMAN def: "Zinc finger protein ZIC 1" [UniProtKB:Q15915] synonym: "Zinc finger protein of the cerebellum 1" EXACT [UniProtKB:Q15915] xref: EMBL:AAI04849.1 xref: EMBL:AAI04851.1 xref: EMBL:BAA11179.1 xref: EMBL:EAW78915.1 xref: UniProtKB:Q15915 xref: UniProtKB:Q2M3N1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020604 ! ZIC1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000826 ! regulation of smoothened signaling pathway [Term] id: CCO:B0024821 name: CEBPZ_HUMAN def: "CCAAT/enhancer-binding protein zeta" [UniProtKB:Q03701] synonym: "CBF" EXACT [UniProtKB:Q03701] synonym: "CCAAT-binding factor" EXACT [UniProtKB:Q03701] synonym: "CCAAT-box-binding transcription factor" EXACT [UniProtKB:Q03701] xref: EMBL:AAA51924.1 xref: EMBL:AAH34475.1 xref: EMBL:AAY14815.1 xref: UniProtKB:Q03701 xref: UniProtKB:Q8NE75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014655 ! CEBPZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052322 ! CEBPZ_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0052323 ! CEBPZ_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0052324 ! CEBPZ_HUMAN-Phosphothreonine233 relationship: transforms_into CCO:B0052325 ! CEBPZ_HUMAN-Phosphoserine629 relationship: transforms_into CCO:B0052326 ! CEBPZ_HUMAN-Phosphoserine835 relationship: transforms_into CCO:B0064251 ! CEBPZ_HUMAN-Phosphoserine973 relationship: transforms_into CCO:B0064252 ! CEBPZ_HUMAN-Phosphoserine978 [Term] id: CCO:B0024842 name: RARB_HUMAN def: "Retinoic acid receptor beta" [UniProtKB:P10826] synonym: "HBV-activated protein" EXACT [UniProtKB:P10826] synonym: "Nuclear receptor subfamily 1 group B member 2" EXACT [UniProtKB:P10826] synonym: "RAR-beta" EXACT [UniProtKB:P10826] synonym: "RAR-epsilon" EXACT [UniProtKB:P10826] xref: EMBL:AAA58728.1 xref: EMBL:AAD45688.1 xref: EMBL:AAH60794.1 xref: EMBL:CAA27637.1 xref: EMBL:CAA30262.1 xref: EMBL:CAA54740.1 xref: EMBL:CAA68398.1 xref: UniProtKB:P10826 xref: UniProtKB:P12891 xref: UniProtKB:Q00989 xref: UniProtKB:Q15298 xref: UniProtKB:Q9UN48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008057 ! RARB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0024846 name: Q3SB16_HUMAN def: "Retinoic acid receptor beta 1'" [UniProtKB:Q3SB16] xref: EMBL:AAZ32403.1 xref: UniProtKB:Q3SB16 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024847 name: Q15156_HUMAN def: "PML-RAR protein" [UniProtKB:Q15156] xref: EMBL:AAA60126.1 xref: UniProtKB:Q15156 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008524 ! PML-RAR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024850 name: Q658K5_HUMAN def: "Putative uncharacterized protein DKFZp761C0417" [UniProtKB:Q658K5] xref: EMBL:CAH56277.1 xref: UniProtKB:Q658K5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008693 ! DKFZp761C0417_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024853 name: RARA_HUMAN def: "Retinoic acid receptor alpha" [UniProtKB:P10276] synonym: "Nuclear receptor subfamily 1 group B member 1" EXACT [UniProtKB:P10276] synonym: "RAR-alpha" EXACT [UniProtKB:P10276] xref: EMBL:AAB00112.1 xref: EMBL:AAB00113.1 xref: EMBL:AAD05222.1 xref: EMBL:AAF87249.1 xref: EMBL:AAH08727.1 xref: EMBL:AAH71733.1 xref: EMBL:BAB62809.1 xref: EMBL:CAA29787.1 xref: EMBL:CAA29829.1 xref: EMBL:CAA39533.1 xref: EMBL:CAA41532.1 xref: UniProtKB:P10276 xref: UniProtKB:P78456 xref: UniProtKB:Q13440 xref: UniProtKB:Q13441 xref: UniProtKB:Q96S41 xref: UniProtKB:Q9NQS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005427 ! RARA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015348 ! rara-rxrg physical interaction relationship: participates_in CCO:I0015433 ! rara-rxrb physical interaction relationship: participates_in CCO:I0016314 ! rar-mbd1-1 physical interaction relationship: participates_in CCO:I0017592 ! rara-ube3a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002838 ! retinoic acid receptor signaling pathway relationship: transforms_into CCO:B0013710 ! RARA_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0013711 ! RARA_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0013712 ! RARA_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0013713 ! RARA_HUMAN-Phosphoserine461 [Term] id: CCO:B0024873 name: NR6A1_HUMAN def: "Nuclear receptor subfamily 6 group A member 1" [UniProtKB:Q15406] synonym: "GCNF" EXACT [UniProtKB:Q15406] synonym: "Germ cell nuclear factor" EXACT [UniProtKB:Q15406] synonym: "hGCNF" EXACT [UniProtKB:Q15406] synonym: "hRTR" EXACT [UniProtKB:Q15406] synonym: "Retinoid receptor-related testis-specific receptor" EXACT [UniProtKB:Q15406] synonym: "RTR" EXACT [UniProtKB:Q15406] xref: EMBL:AAB06335.1 xref: EMBL:AAB50876.1 xref: EMBL:AAB96828.1 xref: EMBL:AAC52054.1 xref: EMBL:AAH30600.1 xref: EMBL:CAA68236.1 xref: EMBL:CAI10960.1 xref: EMBL:CAI13577.1 xref: EMBL:CAI39633.1 xref: UniProtKB:O00551 xref: UniProtKB:O00603 xref: UniProtKB:Q15406 xref: UniProtKB:Q5T6F4 xref: UniProtKB:Q8NHQ0 xref: UniProtKB:Q92898 xref: UniProtKB:Q99802 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007897 ! NR6A1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0020566 ! gnb5-nr6a1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0024874 name: COT1_HUMAN def: "COUP transcription factor 1" [UniProtKB:P10589] synonym: "COUP-TF I" EXACT [UniProtKB:P10589] synonym: "COUP-TF1" EXACT [UniProtKB:P10589] synonym: "Nuclear receptor subfamily 2 group F member 1" EXACT [UniProtKB:P10589] synonym: "V-ERBA-related protein EAR-3" EXACT [UniProtKB:P10589] xref: EMBL:AAH04154.1 xref: EMBL:AAH17493.1 xref: EMBL:CAA31283.1 xref: EMBL:CAA34277.1 xref: UniProtKB:P10589 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007419 ! NR2F1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0024875 name: COT2_HUMAN def: "COUP transcription factor 2" [UniProtKB:P24468] synonym: "Apolipoprotein AI regulatory protein 1" EXACT [UniProtKB:P24468] synonym: "ARP-1" EXACT [UniProtKB:P24468] synonym: "COUP-TF II" EXACT [UniProtKB:P24468] synonym: "COUP-TF2" EXACT [UniProtKB:P24468] synonym: "Nuclear receptor subfamily 2 group F member 2" EXACT [UniProtKB:P24468] xref: EMBL:AAA21479.1 xref: EMBL:AAA86429.1 xref: EMBL:AAB09475.1 xref: EMBL:AAH14664.1 xref: EMBL:AAH42897.1 xref: UniProtKB:P24468 xref: UniProtKB:Q03754 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007420 ! NR2F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0024877 name: Q7Z5U9_HUMAN def: "HNF4G protein" [UniProtKB:Q7Z5U9] xref: EMBL:AAH54009.1 xref: UniProtKB:Q7Z5U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008840 ! HNF4G_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024878 name: RXRB_HUMAN def: "Retinoic acid receptor RXR-beta" [UniProtKB:P28702] synonym: "Nuclear receptor subfamily 2 group B member 2" EXACT [UniProtKB:P28702] synonym: "Retinoid X receptor beta" EXACT [UniProtKB:P28702] xref: EMBL:AAA60293.1 xref: EMBL:AAC18599.1 xref: EMBL:AAD13794.1 xref: EMBL:AAH01167.1 xref: EMBL:CAA20239.1 xref: EMBL:CAA45087.1 xref: UniProtKB:P28702 xref: UniProtKB:P28703 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008140 ! RXRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001238 ! retinoid-X receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015433 ! rara-rxrb physical interaction relationship: participates_in CCO:I0015588 ! rxrb-spop physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024881 name: RXRG_HUMAN def: "Retinoic acid receptor RXR-gamma" [UniProtKB:P48443] synonym: "Nuclear receptor subfamily 2 group B member 3" EXACT [UniProtKB:P48443] synonym: "Retinoid X receptor gamma" EXACT [UniProtKB:P48443] xref: EMBL:AAA80681.1 xref: EMBL:AAH12063.1 xref: EMBL:CAC00596.1 xref: EMBL:CAG32986.1 xref: EMBL:EAW90745.1 xref: UniProtKB:A6NIP1 xref: UniProtKB:P48443 xref: UniProtKB:Q6IBU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008141 ! RXRG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001238 ! retinoid-X receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015348 ! rara-rxrg physical interaction relationship: participates_in CCO:I0019614 ! rxrg-ppara physical interaction relationship: participates_in CCO:I0020586 ! lrsam1-rxrg physical interaction relationship: participates_in CCO:I0020660 ! rxrg-chgb physical interaction relationship: participates_in CCO:I0020661 ! rxrg-loc56902 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024884 name: Q5STQ1_HUMAN def: "Retinoid X receptor, beta" [UniProtKB:Q5STQ1] xref: EMBL:CAI17612.2 xref: EMBL:CAI18064.2 xref: EMBL:CAI41836.2 xref: EMBL:CAQ09065.1 xref: EMBL:CAQ10299.1 xref: EMBL:CAQ11083.1 xref: UniProtKB:Q5JP92 xref: UniProtKB:Q5STQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008140 ! RXRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024886 name: RXRA_HUMAN def: "Retinoic acid receptor RXR-alpha" [UniProtKB:P19793] synonym: "Nuclear receptor subfamily 2 group B member 1" EXACT [UniProtKB:P19793] synonym: "Retinoid X receptor alpha" EXACT [UniProtKB:P19793] xref: EMBL:ABB96254.1 xref: EMBL:CAA36982.1 xref: UniProtKB:P19793 xref: UniProtKB:Q2V504 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008139 ! RXRA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001238 ! retinoid-X receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017652 ! hrmt1l1-rxra-1 physical interaction relationship: participates_in CCO:I0018416 ! ncoa6-rxra-1 physical interaction relationship: participates_in CCO:I0018421 ! ncoa6-rxra-2 physical interaction relationship: participates_in CCO:I0018849 ! edf1-rxra-1 physical interaction relationship: participates_in CCO:I0019673 ! ubqln4-rxra physical interaction relationship: participates_in CCO:I0019862 ! tmprss3-rxra physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:B0024889 name: Q3KQR7_HUMAN def: "NR2F2 protein" [UniProtKB:Q3KQR7] synonym: "cDNA FLJ50900, highly similar to COUP transcription factor 2" EXACT [UniProtKB:Q3KQR7] synonym: "Nuclear receptor subfamily 2, group F, member 2, isoform CRA_b" EXACT [UniProtKB:Q3KQR7] xref: EMBL:AAI06084.1 xref: EMBL:BAG63083.1 xref: EMBL:EAX02196.1 xref: UniProtKB:Q3KQR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007420 ! NR2F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0024893 name: NR2F6_HUMAN def: "Nuclear receptor subfamily 2 group F member 6" [UniProtKB:P10588] synonym: "Orphan nuclear receptor EAR-2" EXACT [UniProtKB:P10588] synonym: "V-erbA-related protein EAR-2" EXACT [UniProtKB:P10588] xref: EMBL:AAH02669.3 xref: EMBL:AAH63018.2 xref: EMBL:AAH84544.2 xref: EMBL:CAA31282.1 xref: UniProtKB:P10588 xref: UniProtKB:Q5XGA0 xref: UniProtKB:Q6P586 xref: UniProtKB:Q9BUE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007896 ! NR2F6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035305 ! NR2F6_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0035306 ! NR2F6_HUMAN-Phosphoserine40 [Term] id: CCO:B0024896 name: A3KGN0_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGN0] xref: EMBL:CAM45784.1 xref: UniProtKB:A3KGN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024897 name: A2ABE9_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A2ABE9] xref: EMBL:CAM24983.1 xref: EMBL:CAM25670.1 xref: EMBL:CAM45782.1 xref: EMBL:CAQ08904.1 xref: EMBL:CAQ10119.1 xref: EMBL:CAQ10623.1 xref: UniProtKB:A2ABE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024899 name: A3KGM9_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGM9] xref: EMBL:CAM45783.1 xref: UniProtKB:A3KGM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024900 name: A2BEX2_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A2BEX2] xref: EMBL:CAM26105.1 xref: EMBL:CAQ07246.1 xref: UniProtKB:A2BEX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024901 name: A3KGM6_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGM6] xref: EMBL:CAM45780.1 xref: UniProtKB:A3KGM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024902 name: Q5SSR2_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:Q5SSR2] xref: EMBL:CAI17722.1 xref: EMBL:CAI18422.1 xref: EMBL:CAM45777.1 xref: EMBL:CAQ07027.1 xref: EMBL:CAQ08903.1 xref: EMBL:CAQ10115.1 xref: UniProtKB:Q5SSR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024905 name: A2BEX3_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A2BEX3] xref: EMBL:CAM26106.1 xref: UniProtKB:A2BEX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024906 name: A2ABF0_HUMAN def: "cDNA FLJ39914 fis, clone SPLEN2018732, highly similar to MutS protein homolog 5" [UniProtKB:A2ABF0] synonym: "MutS homolog 5 (E. coli)" EXACT [UniProtKB:A2ABF0] xref: EMBL:BAG53438.1 xref: EMBL:CAM24984.1 xref: EMBL:CAM25671.1 xref: EMBL:CAM26103.1 xref: EMBL:CAQ07243.1 xref: EMBL:CAQ10120.1 xref: EMBL:CAQ10614.1 xref: UniProtKB:A2ABF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024907 name: A2BEX4_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A2BEX4] xref: EMBL:CAM26107.1 xref: EMBL:CAQ07245.1 xref: UniProtKB:A2BEX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024909 name: A3KGM5_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGM5] xref: EMBL:CAM45779.1 xref: UniProtKB:A3KGM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024910 name: Q5SSQ8_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:Q5SSQ8] xref: EMBL:CAI17726.2 xref: EMBL:CAI18426.2 xref: EMBL:CAQ08902.1 xref: EMBL:CAQ10118.1 xref: EMBL:CAQ10621.1 xref: UniProtKB:Q5SSQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024911 name: A2BEX1_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A2BEX1] xref: EMBL:CAM26104.1 xref: EMBL:CAQ07244.1 xref: UniProtKB:A2BEX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024912 name: A3KGM4_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGM4] xref: EMBL:CAM45778.1 xref: UniProtKB:A3KGM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024914 name: A3KGM7_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGM7] xref: EMBL:CAM45781.1 xref: UniProtKB:A3KGM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0024942 name: Q6NVK3_HUMAN def: "DNA ligase" [UniProtKB:Q6NVK3] synonym: "EC 6.5.1.1" EXACT [UniProtKB:Q6NVK3] xref: EMBL:AAH68005.1 xref: EMBL:EAW80199.1 xref: UniProtKB:Q6NVK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004493 ! LIG3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000414 ! DNA ligase (ATP) activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0024944 name: Q6ZUA5_HUMAN xref: UniProtKB:Q6ZUA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000414 ! DNA ligase (ATP) activity relationship: has_function CCO:F0003433 ! ligase activity relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0024964 name: Q59FA0_HUMAN def: "DNA polymerase" [UniProtKB:Q59FA0] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q59FA0] xref: EMBL:BAD92797.1 xref: UniProtKB:Q59FA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0024966 name: Q308M6_HUMAN def: "DNA polymerase" [UniProtKB:Q308M6] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q308M6] xref: EMBL:ABB29977.1 xref: UniProtKB:Q308M6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0025035 name: Q7Z324_HUMAN def: "Putative uncharacterized protein DKFZp686G05200" [UniProtKB:Q7Z324] xref: EMBL:CAD98057.1 xref: UniProtKB:Q7Z324 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008824 ! DKFZp686G05200_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000244 ! negative regulation of S phase of mitotic cell cycle relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0025042 name: IL3RB_HUMAN def: "Cytokine receptor common subunit beta precursor" [UniProtKB:P32927] synonym: "CD131 antigen" EXACT [UniProtKB:P32927] synonym: "CDw131" EXACT [UniProtKB:P32927] synonym: "GM-CSF/IL-3/IL-5 receptor common beta-chain" EXACT [UniProtKB:P32927] xref: EMBL:AAA18171.1 xref: EMBL:CAG30314.1 xref: EMBL:CAI17999.1 xref: EMBL:CAI23586.1 xref: EMBL:CAQ10438.1 xref: EMBL:CAQ10744.1 xref: EMBL:EAW60125.1 xref: EMBL:EAW60126.1 xref: UniProtKB:P32927 xref: UniProtKB:Q5JZI1 xref: UniProtKB:Q6ICE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007670 ! CSF2RB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: transforms_into CCO:B0034872 ! IL3RB_HUMAN-Phosphotyrosine766 [Term] id: CCO:B0025044 name: KPCG_HUMAN def: "Protein kinase C gamma type" [UniProtKB:P05129] synonym: "EC 2.7.11.13" EXACT [UniProtKB:P05129] synonym: "PKC-gamma" EXACT [UniProtKB:P05129] xref: EMBL:AAA60102.1 xref: EMBL:AAH47876.1 xref: EMBL:AAK13533.1 xref: EMBL:CAA78820.1 xref: UniProtKB:P05129 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007755 ! PRKCG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019153 ! prkcg-prkcabp physical interaction relationship: participates_in CCO:I0019154 ! prkcg-prkcabp-1 physical interaction relationship: participates_in CCO:I0019155 ! prkcg-exoc5 physical interaction relationship: participates_in CCO:I0019156 ! prkcg-cchcr1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001431 ! negative regulation of protein ubiquitination relationship: participates_in CCO:P0001614 ! positive regulation of mismatch repair relationship: transforms_into CCO:B0035056 ! KPCG_HUMAN-Phosphotyrosine195 relationship: transforms_into CCO:B0035057 ! KPCG_HUMAN-Phosphotyrosine312 relationship: transforms_into CCO:B0035058 ! KPCG_HUMAN-Phosphoserine322 relationship: transforms_into CCO:B0035059 ! KPCG_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0035060 ! KPCG_HUMAN-Phosphothreonine514 relationship: transforms_into CCO:B0035061 ! KPCG_HUMAN-Phosphothreonine518 relationship: transforms_into CCO:B0035062 ! KPCG_HUMAN-Phosphothreonine648 relationship: transforms_into CCO:B0035063 ! KPCG_HUMAN-Phosphothreonine655 relationship: transforms_into CCO:B0035064 ! KPCG_HUMAN-Phosphoserine687 [Term] id: CCO:B0025045 name: KPCB_HUMAN def: "Protein kinase C beta type" [UniProtKB:P05771] synonym: "EC 2.7.11.13" EXACT [UniProtKB:P05771] synonym: "PKC-B" EXACT [UniProtKB:P05771] synonym: "PKC-beta" EXACT [UniProtKB:P05771] xref: EMBL:AAA60095.1 xref: EMBL:AAA60096.1 xref: EMBL:AAA60097.1 xref: EMBL:AAB97933.1 xref: EMBL:AAB97934.1 xref: EMBL:AAD13852.1 xref: EMBL:AAH36472.1 xref: EMBL:BAA00912.1 xref: EMBL:CAA05725.1 xref: EMBL:CAA29395.1 xref: EMBL:CAA29396.1 xref: EMBL:CAA29634.1 xref: EMBL:CAA30130.1 xref: EMBL:CAA44393.1 xref: UniProtKB:O43744 xref: UniProtKB:P05127 xref: UniProtKB:P05771 xref: UniProtKB:Q15138 xref: UniProtKB:Q93060 xref: UniProtKB:Q9UE49 xref: UniProtKB:Q9UE50 xref: UniProtKB:Q9UEH8 xref: UniProtKB:Q9UJ30 xref: UniProtKB:Q9UJ33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018432 ! PRKCB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0035039 ! KPCB_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035040 ! KPCB_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0035041 ! KPCB_HUMAN-Phosphothreonine17 relationship: transforms_into CCO:B0035042 ! KPCB_HUMAN-Phosphotyrosine195 relationship: transforms_into CCO:B0035043 ! KPCB_HUMAN-Phosphothreonine314 relationship: transforms_into CCO:B0035044 ! KPCB_HUMAN-Phosphothreonine324 relationship: transforms_into CCO:B0035045 ! KPCB_HUMAN-Phosphothreonine500 relationship: transforms_into CCO:B0035046 ! KPCB_HUMAN-Phosphothreonine504 relationship: transforms_into CCO:B0035047 ! KPCB_HUMAN-Phosphothreonine635 relationship: transforms_into CCO:B0035048 ! KPCB_HUMAN-Phosphothreonine642 relationship: transforms_into CCO:B0035049 ! KPCB_HUMAN-Phosphoserine661 [Term] id: CCO:B0025046 name: KPCL_HUMAN def: "Protein kinase C eta type" [UniProtKB:P24723] synonym: "EC 2.7.11.13" EXACT [UniProtKB:P24723] synonym: "nPKC-eta" EXACT [UniProtKB:P24723] synonym: "PKC-L" EXACT [UniProtKB:P24723] xref: EMBL:AAA60100.1 xref: EMBL:AAB32724.1 xref: EMBL:AAH37268.1 xref: EMBL:BAF82872.1 xref: EMBL:EAW80801.1 xref: UniProtKB:P24723 xref: UniProtKB:Q16246 xref: UniProtKB:Q8NE03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007756 ! PRKCH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0067427 ! KPCL_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0067428 ! KPCL_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0067429 ! KPCL_HUMAN-Phosphothreonine513 relationship: transforms_into CCO:B0067430 ! KPCL_HUMAN-Phosphothreonine656 relationship: transforms_into CCO:B0067431 ! KPCL_HUMAN-Phosphoserine675 [Term] id: CCO:B0025049 name: A6PVX6_HUMAN def: "Protein kinase C, zeta" [UniProtKB:A6PVX6] xref: EMBL:CAO72063.1 xref: EMBL:CAO72114.1 xref: EMBL:CAO72142.1 xref: UniProtKB:A6PVX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004959 ! PRKCZ_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0025051 name: Q5JUN8_HUMAN def: "Protein kinase C, theta" [UniProtKB:Q5JUN8] xref: EMBL:CAI15756.1 xref: EMBL:CAI16127.1 xref: UniProtKB:Q5JUN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007757 ! PRKCQ_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0025052 name: Q7Z727_HUMAN def: "PRKCA protein" [UniProtKB:Q7Z727] xref: EMBL:AAH53321.1 xref: UniProtKB:Q7Z727 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004957 ! PRKCA_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0025053 name: KPCT_HUMAN def: "Protein kinase C theta type" [UniProtKB:Q04759] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q04759] synonym: "nPKC-theta" EXACT [UniProtKB:Q04759] xref: EMBL:AAA60101.1 xref: EMBL:AAA75571.1 xref: EMBL:AAI01466.1 xref: EMBL:AAI13360.1 xref: EMBL:AAU29340.1 xref: EMBL:CAC10200.2 xref: EMBL:CAC12904.2 xref: UniProtKB:Q04759 xref: UniProtKB:Q14DH6 xref: UniProtKB:Q3MJF1 xref: UniProtKB:Q64FY5 xref: UniProtKB:Q9H508 xref: UniProtKB:Q9H549 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007757 ! PRKCQ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016125 ! btk-prkcq-2 physical interaction relationship: participates_in CCO:I0018137 ! prkcq-txnl2-3 physical interaction relationship: participates_in CCO:I0018138 ! prkcq-txnl2-4 colocalization relationship: participates_in CCO:I0018175 ! prkcq-txnl2-5 physical interaction relationship: participates_in CCO:I0018588 ! prkcq-txnl2-2 physical interaction relationship: participates_in CCO:I0018838 ! btk-prkcq-1 physical interaction relationship: participates_in CCO:I0019225 ! prkcq-txnl2-1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0035068 ! KPCT_HUMAN-Phosphothreonine219 relationship: transforms_into CCO:B0035069 ! KPCT_HUMAN-Phosphothreonine538 relationship: transforms_into CCO:B0035070 ! KPCT_HUMAN-Phosphoserine676 relationship: transforms_into CCO:B0035071 ! KPCT_HUMAN-Phosphoserine685 relationship: transforms_into CCO:B0035072 ! KPCT_HUMAN-Phosphoserine695 [Term] id: CCO:B0025054 name: KPCE_HUMAN def: "Protein kinase C epsilon type" [UniProtKB:Q02156] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q02156] synonym: "nPKC-epsilon" EXACT [UniProtKB:Q02156] xref: EMBL:AAD08855.1 xref: EMBL:AAI09034.1 xref: EMBL:AAI09035.1 xref: EMBL:AAX93253.1 xref: EMBL:AAY14773.1 xref: EMBL:CAA46388.1 xref: UniProtKB:Q02156 xref: UniProtKB:Q32MQ3 xref: UniProtKB:Q53SL4 xref: UniProtKB:Q53SM5 xref: UniProtKB:Q9UE81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007754 ! PRKCE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0035050 ! KPCE_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0035051 ! KPCE_HUMAN-Phosphothreonine349 relationship: transforms_into CCO:B0035052 ! KPCE_HUMAN-Phosphothreonine566 relationship: transforms_into CCO:B0035053 ! KPCE_HUMAN-Phosphothreonine703 relationship: transforms_into CCO:B0035054 ! KPCE_HUMAN-Phosphothreonine710 relationship: transforms_into CCO:B0035055 ! KPCE_HUMAN-Phosphoserine729 relationship: transforms_into CCO:B0067425 ! KPCE_HUMAN-Phosphothreonine309 relationship: transforms_into CCO:B0067426 ! KPCE_HUMAN-Phosphoserine316 [Term] id: CCO:B0025068 name: PDZD1_HUMAN def: "PDZ domain-containing protein 1" [UniProtKB:Q5T2W1] synonym: "CFTR-associated protein of 70 kDa" EXACT [UniProtKB:Q5T2W1] synonym: "Na(+)/H(+) exchanger regulatory factor 3" EXACT [UniProtKB:Q5T2W1] synonym: "Na/Pi cotransporter C-terminal-associated protein" EXACT [UniProtKB:Q5T2W1] synonym: "NaPi-Cap1" EXACT [UniProtKB:Q5T2W1] synonym: "Sodium-hydrogen exchanger regulatory factor 3" EXACT [UniProtKB:Q5T2W1] xref: EMBL:AAC12264.1 xref: EMBL:AAH06496.1 xref: EMBL:AAH06518.1 xref: EMBL:CAI13715.1 xref: EMBL:CAI13716.1 xref: UniProtKB:O60450 xref: UniProtKB:Q5T2W1 xref: UniProtKB:Q5T5P6 xref: UniProtKB:Q9BQ41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019352 ! PDZK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015616 ! gfap-pdzk1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0069193 ! PDZD1_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0069194 ! PDZD1_HUMAN-Phosphoserine514 [Term] id: CCO:B0025069 name: NHRF2_HUMAN def: "Na(+)/H(+) exchange regulatory cofactor NHE-RF2" [UniProtKB:Q15599] synonym: "NHE3 kinase A regulatory protein E3KARP" EXACT [UniProtKB:Q15599] synonym: "NHERF-2" EXACT [UniProtKB:Q15599] synonym: "SIP-1" EXACT [UniProtKB:Q15599] synonym: "Sodium-hydrogen exchanger regulatory factor 2" EXACT [UniProtKB:Q15599] synonym: "Solute carrier family 9 isoform A3 regulatory factor 2" EXACT [UniProtKB:Q15599] synonym: "SRY-interacting protein 1" EXACT [UniProtKB:Q15599] synonym: "TKA-1" EXACT [UniProtKB:Q15599] synonym: "Tyrosine kinase activator protein 1" EXACT [UniProtKB:Q15599] xref: EMBL:AAB53042.1 xref: EMBL:AAC34208.1 xref: EMBL:AAC52090.1 xref: EMBL:AAC63061.1 xref: EMBL:AAH14513.2 xref: EMBL:AAI06002.1 xref: EMBL:BAA32696.1 xref: EMBL:BAA33216.1 xref: EMBL:CAA90511.1 xref: UniProtKB:O00272 xref: UniProtKB:O00556 xref: UniProtKB:Q15599 xref: UniProtKB:Q3KQY7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022444 ! SLC9A3R2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0017797 ! cftr-slc9a3r2-2 physical interaction relationship: participates_in CCO:I0017798 ! cftr-slc9a3r2-3 physical interaction relationship: participates_in CCO:I0019328 ! cftr-slc9a3r2 physical interaction relationship: participates_in CCO:I0019329 ! cftr-slc9a3r2-1 physical interaction relationship: transforms_into CCO:B0068715 ! NHRF2_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0068716 ! NHRF2_HUMAN-Phosphoserine254 relationship: transforms_into CCO:B0068717 ! NHRF2_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0068718 ! NHRF2_HUMAN-Phosphoserine275 [Term] id: CCO:B0025070 name: PDZD3_HUMAN def: "PDZ domain-containing protein 3" [UniProtKB:Q86UT5] synonym: "Intestinal and kidney-enriched PDZ protein" EXACT [UniProtKB:Q86UT5] synonym: "PDZ domain-containing protein 2" EXACT [UniProtKB:Q86UT5] xref: EMBL:AAH29042.1 xref: EMBL:AAL10686.1 xref: EMBL:BAB15474.1 xref: EMBL:BAC03780.1 xref: EMBL:BAC76050.1 xref: UniProtKB:Q86UT5 xref: UniProtKB:Q8N6R4 xref: UniProtKB:Q8NAW7 xref: UniProtKB:Q8NEX7 xref: UniProtKB:Q9H5Z3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019353 ! PDZD3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001779 ! ion channel inhibitor activity relationship: has_function CCO:F0004361 ! guanylate cyclase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001604 ! subapical complex relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:P0000711 ! receptor guanylyl cyclase signaling pathway relationship: participates_in CCO:P0001150 ! cGMP-mediated signaling relationship: participates_in CCO:P0001320 ! negative regulation of cGMP biosynthetic process [Term] id: CCO:B0025071 name: NHERF_HUMAN def: "Ezrin-radixin-moesin-binding phosphoprotein 50" [UniProtKB:O14745] synonym: "EBP50" EXACT [UniProtKB:O14745] synonym: "Na(+)/H(+) exchange regulatory cofactor NHE-RF" EXACT [UniProtKB:O14745] synonym: "NHERF-1" EXACT [UniProtKB:O14745] synonym: "Regulatory cofactor of Na(+)/H(+) exchanger" EXACT [UniProtKB:O14745] synonym: "Sodium-hydrogen exchanger regulatory factor 1" EXACT [UniProtKB:O14745] synonym: "Solute carrier family 9 isoform A3 regulatory factor 1" EXACT [UniProtKB:O14745] xref: EMBL:AAC04572.1 xref: EMBL:AAC52084.1 xref: EMBL:AAH01443.1 xref: EMBL:AAH03361.1 xref: EMBL:AAH11777.1 xref: EMBL:AAH49220.1 xref: EMBL:AAH53350.1 xref: UniProtKB:O14745 xref: UniProtKB:O43552 xref: UniProtKB:Q86WQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018787 ! SLC9A3R1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0018190 ! msn-nherf-2 physical interaction relationship: participates_in CCO:I0018191 ! msn-nherf-3 physical interaction relationship: participates_in CCO:I0018285 ! clcn3-slc9a3r1-1 physical interaction relationship: participates_in CCO:I0018287 ! cftr-slc9a3r1-1 physical interaction relationship: participates_in CCO:I0019366 ! msn-nherf-1 direct interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0068707 ! NHERF_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0068708 ! NHERF_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0068709 ! NHERF_HUMAN-Phosphoserine288 relationship: transforms_into CCO:B0068710 ! NHERF_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0068711 ! NHERF_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0068712 ! NHERF_HUMAN-Phosphothreonine293 relationship: transforms_into CCO:B0068713 ! NHERF_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0068714 ! NHERF_HUMAN-Phosphoserine302 [Term] id: CCO:B0025086 name: Q6Q9Z7_HUMAN def: "E2F6 splice variant a" [UniProtKB:Q6Q9Z7] xref: EMBL:AAT02636.1 xref: UniProtKB:Q6Q9Z7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004538 ! E2F6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025091 name: Q5SRN1_HUMAN def: "Cell division cycle 40 homolog (S. cerevisiae)" [UniProtKB:Q5SRN1] xref: EMBL:CAI13321.1 xref: EMBL:CAI22519.1 xref: UniProtKB:Q5SRN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008012 ! CDC40_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0025098 name: LETM1_HUMAN def: "LETM1 and EF-hand domain-containing protein 1, mitochondrial precursor" [UniProtKB:O95202] synonym: "Leucine zipper-EF-hand-containing transmembrane protein 1" EXACT [UniProtKB:O95202] xref: EMBL:AAD13138.1 xref: EMBL:AAH14500.1 xref: EMBL:AAH21208.1 xref: EMBL:CAB63769.2 xref: UniProtKB:O95202 xref: UniProtKB:Q9UF65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018474 ! LETM1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0025107 name: COR1B_HUMAN def: "Coronin-1B" [UniProtKB:Q9BR76] synonym: "Coronin-2" EXACT [UniProtKB:Q9BR76] xref: EMBL:AAH06449.1 xref: UniProtKB:Q9BR76 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007414 ! CORO1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0034681 ! COR1B_HUMAN-Phosphoserine2 [Term] id: CCO:B0025112 name: COR2A_HUMAN def: "Coronin-2A" [UniProtKB:Q92828] synonym: "IR10" EXACT [UniProtKB:Q92828] synonym: "WD repeat-containing protein 2" EXACT [UniProtKB:Q92828] xref: EMBL:AAB47807.1 xref: EMBL:AAB47808.1 xref: EMBL:AAH00010.1 xref: EMBL:AAH11690.1 xref: UniProtKB:Q92828 xref: UniProtKB:Q92829 xref: UniProtKB:Q9BWS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007416 ! CORO2A_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0025115 name: COR1C_HUMAN def: "Coronin-1C" [UniProtKB:Q9ULV4] synonym: "Coronin-3" EXACT [UniProtKB:Q9ULV4] synonym: "hCRNN4" EXACT [UniProtKB:Q9ULV4] xref: EMBL:AAH02342.1 xref: EMBL:BAA83077.1 xref: EMBL:CAB82406.1 xref: UniProtKB:Q9NSK5 xref: UniProtKB:Q9ULV4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007415 ! CORO1C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016679 ! map3k3-coro1c physical interaction relationship: transforms_into CCO:B0034682 ! COR1C_HUMAN-Phosphotyrosine301 [Term] id: CCO:B0025120 name: Q59FX3_HUMAN def: "Neurofibromin variant" [UniProtKB:Q59FX3] xref: EMBL:BAD92573.1 xref: UniProtKB:Q59FX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0025166 name: TRPC4_HUMAN def: "Short transient receptor potential channel 4" [UniProtKB:Q9UBN4] synonym: "hTrp-4" EXACT [UniProtKB:Q9UBN4] synonym: "hTrp4" EXACT [UniProtKB:Q9UBN4] synonym: "Trp-related protein 4" EXACT [UniProtKB:Q9UBN4] synonym: "TrpC4" EXACT [UniProtKB:Q9UBN4] xref: EMBL:AAC50630.1 xref: EMBL:AAD51736.1 xref: EMBL:AAF22927.1 xref: EMBL:AAF22928.1 xref: EMBL:AAF22929.1 xref: EMBL:AAF22930.1 xref: EMBL:AAL24549.1 xref: EMBL:AAL24550.1 xref: UniProtKB:Q15721 xref: UniProtKB:Q9UBN4 xref: UniProtKB:Q9UIB0 xref: UniProtKB:Q9UIB1 xref: UniProtKB:Q9UIB2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008323 ! TRPC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017403 ! mx1-trpc4-2 physical interaction relationship: participates_in CCO:I0019451 ! mx1-trpc4-1 physical interaction relationship: transforms_into CCO:B0035816 ! TRPC4_HUMAN-Phosphoserine193 relationship: transforms_into CCO:B0035817 ! TRPC4_HUMAN-Phosphoserine195 [Term] id: CCO:B0025167 name: TRPC5_HUMAN def: "Short transient receptor potential channel 5" [UniProtKB:Q9UL62] synonym: "Htrp-5" EXACT [UniProtKB:Q9UL62] synonym: "Htrp5" EXACT [UniProtKB:Q9UL62] synonym: "TrpC5" EXACT [UniProtKB:Q9UL62] xref: EMBL:AAC24563.1 xref: EMBL:AAF00002.1 xref: EMBL:CAI43017.1 xref: UniProtKB:O75233 xref: UniProtKB:Q5JXY8 xref: UniProtKB:Q9UL62 xref: UniProtKB:Q9Y514 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008324 ! TRPC5_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002736 ! store-operated calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019452 ! mx1-trpc5-1 physical interaction [Term] id: CCO:B0025169 name: TRPC1_HUMAN def: "Short transient receptor potential channel 1" [UniProtKB:P48995] synonym: "Transient receptor protein 1" EXACT [UniProtKB:P48995] synonym: "TRP-1" EXACT [UniProtKB:P48995] synonym: "TrpC1" EXACT [UniProtKB:P48995] xref: EMBL:AAA93251.1 xref: EMBL:AAA93252.1 xref: EMBL:CAA61447.1 xref: EMBL:CAA98108.1 xref: UniProtKB:P48995 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008322 ! TRPC1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002736 ! store-operated calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017401 ! mx1-trpc1-1 physical interaction [Term] id: CCO:B0025184 name: IL6RB_HUMAN def: "Interleukin-6 receptor subunit beta precursor" [UniProtKB:P40189] synonym: "CD130 antigen" EXACT [UniProtKB:P40189] synonym: "CDw130" EXACT [UniProtKB:P40189] synonym: "gp130" EXACT [UniProtKB:P40189] synonym: "IL-6R-beta" EXACT [UniProtKB:P40189] synonym: "Interleukin-6 signal transducer" EXACT [UniProtKB:P40189] synonym: "Membrane glycoprotein 130" EXACT [UniProtKB:P40189] synonym: "Oncostatin-M receptor alpha subunit" EXACT [UniProtKB:P40189] xref: EMBL:AAA59155.1 xref: EMBL:ABK41905.1 xref: EMBL:BAA78112.1 xref: EMBL:EAW54936.1 xref: UniProtKB:A0N0L4 xref: UniProtKB:P40189 xref: UniProtKB:Q9UQ41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007671 ! IL6ST_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001262 ! interleukin-6 receptor activity relationship: has_function CCO:F0001269 ! oncostatin-M receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017786 ! il6st-lif-1 direct interaction relationship: participates_in CCO:I0018118 ! il6-il6r-1 physical interaction relationship: participates_in CCO:I0018404 ! il6st-ptpn1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0034873 ! IL6RB_HUMAN-Phosphoserine667 relationship: transforms_into CCO:B0034874 ! IL6RB_HUMAN-Phosphoserine782 relationship: transforms_into CCO:B0034875 ! IL6RB_HUMAN-Phosphoserine820 relationship: transforms_into CCO:B0034876 ! IL6RB_HUMAN-Phosphoserine829 [Term] id: CCO:B0025212 name: SBDS_HUMAN def: "Ribosome maturation protein SBDS" [UniProtKB:Q9Y3A5] synonym: "Shwachman-Bodian-Diamond syndrome protein" EXACT [UniProtKB:Q9Y3A5] xref: EMBL:AAD34092.1 xref: EMBL:AAH65700.1 xref: EMBL:AAN77490.1 xref: EMBL:BAA91905.1 xref: UniProtKB:Q96FX0 xref: UniProtKB:Q9NV53 xref: UniProtKB:Q9Y3A5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014363 ! SBDS_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000234 ! mitotic spindle stabilization relationship: participates_in CCO:P0000477 ! inner cell mass cell proliferation relationship: transforms_into CCO:B0048384 ! SBDS_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0048385 ! SBDS_HUMAN-Phosphothreonine124 relationship: transforms_into CCO:B0048386 ! SBDS_HUMAN-Phosphotyrosine128 [Term] id: CCO:B0025227 name: EMI5_HUMAN def: "Protein EMI5 homolog, mitochondrial precursor" [UniProtKB:Q9NX18] xref: EMBL:AAH02331.1 xref: EMBL:BAA91204.1 xref: UniProtKB:Q9NX18 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007487 ! C11orf79_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0019719 ! flj20487-ikbkap physical interaction [Term] id: CCO:B0025289 name: AFG32_HUMAN def: "AFG3-like protein 2" [UniProtKB:Q9Y4W6] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q9Y4W6] synonym: "Paraplegin-like protein" EXACT [UniProtKB:Q9Y4W6] xref: EMBL:AAH65016.1 xref: EMBL:CAB48398.1 xref: UniProtKB:Q6P1L0 xref: UniProtKB:Q9Y4W6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007222 ! AFG3L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016983 ! tnfrsf1a-afg3l2 physical interaction relationship: transforms_into CCO:B0034526 ! AFG32_HUMAN-N6-acetyllysine308 relationship: transforms_into CCO:B0034527 ! AFG32_HUMAN-N6-acetyllysine543 [Term] id: CCO:B0025350 name: DIRA1_HUMAN def: "GTP-binding protein Di-Ras1" [UniProtKB:O95057] synonym: "Distinct subgroup of the Ras family member 1" EXACT [UniProtKB:O95057] synonym: "Ras-related inhibitor of cell growth" EXACT [UniProtKB:O95057] synonym: "Rig" EXACT [UniProtKB:O95057] synonym: "Small GTP-binding tumor suppressor 1" EXACT [UniProtKB:O95057] xref: EMBL:AAD13119.1 xref: EMBL:AAH30660.1 xref: EMBL:AAL17968.1 xref: EMBL:AAL23715.1 xref: EMBL:AAO22153.1 xref: EMBL:BAC01115.1 xref: UniProtKB:O95057 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007460 ! DIRAS1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0025365 name: OVOL2_HUMAN def: "Transcription factor Ovo-like 2" [UniProtKB:Q9BRP0] synonym: "hOvo2" EXACT [UniProtKB:Q9BRP0] synonym: "Zinc finger protein 339" EXACT [UniProtKB:Q9BRP0] xref: EMBL:AAH06148.1 xref: EMBL:AAP35959.1 xref: EMBL:BAB14002.1 xref: EMBL:CAB45151.1 xref: EMBL:CAI14857.1 xref: EMBL:CAI22534.1 xref: UniProtKB:Q5T8B4 xref: UniProtKB:Q9BRP0 xref: UniProtKB:Q9BX22 xref: UniProtKB:Q9HA54 xref: UniProtKB:Q9Y4M0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007941 ! OVOL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025401 name: MS4A7_HUMAN def: "Membrane-spanning 4-domains subfamily A member 7" [UniProtKB:Q9GZW8] synonym: "CD20 antigen" EXACT [UniProtKB:Q9GZW8] synonym: "CD20 antigen-like 4" EXACT [UniProtKB:Q9GZW8] synonym: "CD20/FC-epsilon-RI-beta family member 4" EXACT [UniProtKB:Q9GZW8] synonym: "Four-span transmembrane protein 2" EXACT [UniProtKB:Q9GZW8] xref: EMBL:AAF17243.1 xref: EMBL:AAG30930.1 xref: EMBL:AAH20673.1 xref: EMBL:AAK37599.1 xref: EMBL:AAL56221.1 xref: EMBL:BAB18755.1 xref: EMBL:BAC11405.1 xref: UniProtKB:Q9GZW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007838 ! MS4A7_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020375 ! ms4a7-hmgcl physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0025403 name: A6NP53_HUMAN def: "Putative uncharacterized protein" [UniProtKB:A6NP53] xref: EMBL:BAG59556.1 xref: EMBL:EAW73879.1 xref: UniProtKB:A6NP53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007838 ! MS4A7_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0025407 name: NFIX_HUMAN def: "Nuclear factor 1 X-type" [UniProtKB:Q14938] synonym: "CCAAT-box-binding transcription factor" EXACT [UniProtKB:Q14938] synonym: "CTF" EXACT [UniProtKB:Q14938] synonym: "NF-I/X" EXACT [UniProtKB:Q14938] synonym: "NF1-X" EXACT [UniProtKB:Q14938] synonym: "NFI-X" EXACT [UniProtKB:Q14938] synonym: "Nuclear factor 1/X" EXACT [UniProtKB:Q14938] synonym: "TGGCA-binding protein" EXACT [UniProtKB:Q14938] xref: EMBL:AAA53422.1 xref: EMBL:AAA93126.1 xref: EMBL:AAB52369.1 xref: EMBL:AAB52371.1 xref: EMBL:AAC15752.1 xref: EMBL:AAD38240.1 xref: EMBL:AAD38241.1 xref: UniProtKB:O60413 xref: UniProtKB:Q12859 xref: UniProtKB:Q13050 xref: UniProtKB:Q13052 xref: UniProtKB:Q14938 xref: UniProtKB:Q9UPH1 xref: UniProtKB:Q9Y6R8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018778 ! NFIX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068658 ! NFIX_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0068659 ! NFIX_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0068660 ! NFIX_HUMAN-Phosphoserine288 [Term] id: CCO:B0025409 name: Q7Z3K7_HUMAN def: "Nuclear factor 1" [UniProtKB:Q7Z3K7] xref: EMBL:CAD97845.1 xref: UniProtKB:Q7Z3K7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021217 ! DKFZp686I05275_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025410 name: Q5W0Y9_HUMAN def: "Nuclear factor I/B" [UniProtKB:Q5W0Y9] xref: EMBL:CAH73588.1 xref: UniProtKB:Q5W0Y9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018773 ! NFIB_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025412 name: NFIC_HUMAN def: "Nuclear factor 1 C-type" [UniProtKB:P08651] synonym: "CCAAT-box-binding transcription factor" EXACT [UniProtKB:P08651] synonym: "CTF" EXACT [UniProtKB:P08651] synonym: "NF-I/C" EXACT [UniProtKB:P08651] synonym: "NF1-C" EXACT [UniProtKB:P08651] synonym: "NFI-C" EXACT [UniProtKB:P08651] synonym: "Nuclear factor 1/C" EXACT [UniProtKB:P08651] synonym: "TGGCA-binding protein" EXACT [UniProtKB:P08651] xref: EMBL:AAC32593.1 xref: EMBL:AAC32594.1 xref: EMBL:AAC33190.1 xref: EMBL:AAC33191.1 xref: EMBL:AAC33192.1 xref: EMBL:AAC62842.1 xref: EMBL:AAH12120.1 xref: EMBL:CAA31012.1 xref: EMBL:CAA63440.1 xref: UniProtKB:P08651 xref: UniProtKB:P08652 xref: UniProtKB:Q14932 xref: UniProtKB:Q9UPJ3 xref: UniProtKB:Q9UPJ9 xref: UniProtKB:Q9UPK0 xref: UniProtKB:Q9UPK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018774 ! NFIC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015003 ! mgc14817-nfic physical interaction relationship: participates_in CCO:I0015076 ! nfic-zcchc14 physical interaction relationship: participates_in CCO:I0015080 ! nfic-znf167 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068646 ! NFIC_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0068647 ! NFIC_HUMAN-Phosphoserine194 relationship: transforms_into CCO:B0068648 ! NFIC_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0068649 ! NFIC_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0068650 ! NFIC_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0068651 ! NFIC_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0068652 ! NFIC_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0068653 ! NFIC_HUMAN-Phosphoserine339 relationship: transforms_into CCO:B0068654 ! NFIC_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0068655 ! NFIC_HUMAN-Phosphothreonine378 [Term] id: CCO:B0025414 name: NFIB_HUMAN def: "Nuclear factor 1 B-type" [UniProtKB:O00712] synonym: "CCAAT-box-binding transcription factor" EXACT [UniProtKB:O00712] synonym: "CTF" EXACT [UniProtKB:O00712] synonym: "NF-I/B" EXACT [UniProtKB:O00712] synonym: "NF1-B" EXACT [UniProtKB:O00712] synonym: "NFI-B" EXACT [UniProtKB:O00712] synonym: "Nuclear factor 1/B" EXACT [UniProtKB:O00712] synonym: "TGGCA-binding protein" EXACT [UniProtKB:O00712] xref: EMBL:AAA93125.1 xref: EMBL:AAB41899.1 xref: EMBL:AAB51197.1 xref: EMBL:AAH01283.1 xref: EMBL:AAP35930.1 xref: UniProtKB:O00166 xref: UniProtKB:O00712 xref: UniProtKB:Q12858 xref: UniProtKB:Q96J45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018773 ! NFIB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068642 ! NFIB_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0068643 ! NFIB_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0068644 ! NFIB_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0068645 ! NFIB_HUMAN-Phosphoserine295 [Term] id: CCO:B0025416 name: NFIA_HUMAN def: "Nuclear factor 1 A-type" [UniProtKB:Q12857] synonym: "CCAAT-box-binding transcription factor" EXACT [UniProtKB:Q12857] synonym: "CTF" EXACT [UniProtKB:Q12857] synonym: "NF-I/A" EXACT [UniProtKB:Q12857] synonym: "NF1-A" EXACT [UniProtKB:Q12857] synonym: "NFI-A" EXACT [UniProtKB:Q12857] synonym: "Nuclear factor 1/A" EXACT [UniProtKB:Q12857] synonym: "TGGCA-binding protein" EXACT [UniProtKB:Q12857] xref: EMBL:AAA93124.1 xref: EMBL:BAA92677.1 xref: EMBL:CAI13081.1 xref: EMBL:CAI23240.1 xref: UniProtKB:Q12857 xref: UniProtKB:Q9H3X9 xref: UniProtKB:Q9P2A9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018772 ! NFIA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068635 ! NFIA_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0068636 ! NFIA_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0068637 ! NFIA_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0068638 ! NFIA_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0068639 ! NFIA_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0068640 ! NFIA_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0068641 ! NFIA_HUMAN-Phosphoserine319 [Term] id: CCO:B0025417 name: Q8TA97_HUMAN def: "Nuclear factor 1" [UniProtKB:Q8TA97] xref: EMBL:AAH22264.1 xref: EMBL:CAI13080.1 xref: EMBL:CAI23241.1 xref: EMBL:EAX06601.1 xref: UniProtKB:Q8TA97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018772 ! NFIA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025419 name: Q6ZNF9_HUMAN def: "Nuclear factor 1" [UniProtKB:Q6ZNF9] xref: EMBL:BAD18416.1 xref: UniProtKB:Q6ZNF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025421 name: Q5VW27_HUMAN def: "Nuclear factor 1" [UniProtKB:Q5VW27] xref: EMBL:CAH71973.1 xref: EMBL:CAH73583.1 xref: EMBL:EAW58696.1 xref: UniProtKB:Q5VW27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018773 ! NFIB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025422 name: Q13051_HUMAN def: "Nuclear factor 1" [UniProtKB:Q13051] xref: EMBL:AAB52370.1 xref: UniProtKB:Q13051 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021085 ! NFI_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025423 name: Q5VW31_HUMAN def: "Nuclear factor I/B" [UniProtKB:Q5VW31] xref: EMBL:CAH71969.1 xref: UniProtKB:Q5VW31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018773 ! NFIB_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025428 name: Q5VW30_HUMAN def: "Nuclear factor 1" [UniProtKB:Q5VW30] xref: EMBL:CAH71970.1 xref: EMBL:CAH73584.1 xref: EMBL:EAW58695.1 xref: UniProtKB:Q5VW30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018773 ! NFIB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025429 name: Q5VW29_HUMAN def: "Nuclear factor 1" [UniProtKB:Q5VW29] xref: EMBL:CAH71971.1 xref: EMBL:CAH73585.1 xref: EMBL:EAW58699.1 xref: UniProtKB:Q5VW29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018773 ! NFIB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025430 name: Q5VW26_HUMAN def: "Nuclear factor 1" [UniProtKB:Q5VW26] xref: EMBL:CAH71974.1 xref: EMBL:CAH73587.1 xref: EMBL:EAW58698.1 xref: UniProtKB:Q5VW26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018773 ! NFIB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025434 name: Q59F49_HUMAN def: "Minichromosome maintenance deficient protein 5 variant" [UniProtKB:Q59F49] xref: EMBL:BAD92849.1 xref: UniProtKB:Q59F49 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000634 ! DNA replication initiation [Term] id: CCO:B0025452 name: Q15157_HUMAN def: "Postmeiotic segregation increased 2-like protein 5." [UniProtKB:Q15157] xref: EMBL:BAA07471.1 xref: EMBL:BAA07514.1 xref: UniProtKB:Q15157 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011846 ! PMS2L5_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025454 name: A4D2C1_HUMAN def: "Similar to PMS4 homolog mismatch repair protein-human" [UniProtKB:A4D2C1] xref: EMBL:EAL23841.1 xref: UniProtKB:A4D2C1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011795 ! LOC389527_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025455 name: PMS2L_HUMAN def: "Protein PMS2CL" [UniProtKB:Q68D20] synonym: "PMS2-C terminal-like protein" EXACT [UniProtKB:Q68D20] xref: EMBL:AAH41364.1 xref: EMBL:BAC81643.1 xref: EMBL:CAH18410.1 xref: UniProtKB:Q68D20 xref: UniProtKB:Q764P1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011623 ! PMS2CL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0039594 ! PMS2L_HUMAN-Phosphoserine92 [Term] id: CCO:B0025457 name: PMS4L_HUMAN def: "Postmeiotic segregation increased 4-like protein" [UniProtKB:A4D2C0] xref: EMBL:EAL23839.1 xref: EMBL:EAL23840.1 xref: UniProtKB:A4D2B9 xref: UniProtKB:A4D2C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011624 ! PMS4L_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025458 name: Q5FBW8_HUMAN def: "Postmeiotic segregation increased 2 nirs variant 5" [UniProtKB:Q5FBW8] xref: EMBL:BAD89429.1 xref: UniProtKB:Q5FBW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005346 ! PMS2_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025459 name: PM2L2_HUMAN def: "Postmeiotic segregation increased 2-like protein 2" [UniProtKB:O95744] synonym: "Postmeiotic segregation increased 2-like protein 14" EXACT [UniProtKB:O95744] synonym: "Postmeiotic segregation increased protein 4" EXACT [UniProtKB:O95744] xref: EMBL:BAA74754.1 xref: UniProtKB:O95744 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011619 ! PMS2L2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025462 name: Q16603_HUMAN def: "PMS5 protein" [UniProtKB:Q16603] synonym: "HPMS5 protein" EXACT [UniProtKB:Q16603] xref: EMBL:BAA07472.1 xref: EMBL:BAA07510.1 xref: UniProtKB:Q16603 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011849 ! PMS5_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025463 name: PM2L1_HUMAN def: "Postmeiotic segregation increased 2-like protein 1" [UniProtKB:A4D2B8] synonym: "hPMS3" EXACT [UniProtKB:A4D2B8] synonym: "Postmeiotic segregation increased 2-like protein 13" EXACT [UniProtKB:A4D2B8] synonym: "Postmeiotic segregation increased 2-like protein 6" EXACT [UniProtKB:A4D2B8] synonym: "Postmeiotic segregation increased protein 3" EXACT [UniProtKB:A4D2B8] synonym: "Postmeiotic segregation increased protein 8" EXACT [UniProtKB:A4D2B8] xref: EMBL:AAH67809.1 xref: EMBL:AAI10396.1 xref: EMBL:BAA07470.1 xref: EMBL:BAA07511.1 xref: EMBL:BAA74753.1 xref: EMBL:EAL23838.1 xref: EMBL:EAW76560.1 xref: UniProtKB:A4D2B8 xref: UniProtKB:Q0VGD2 xref: UniProtKB:Q16530 xref: UniProtKB:Q6NVZ2 xref: UniProtKB:Q7KZ90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011618 ! PMS2L1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025464 name: PM2L8_HUMAN def: "Postmeiotic segregation increased 2-like protein 8" [UniProtKB:Q13400] synonym: "PMS2-related protein 2" EXACT [UniProtKB:Q13400] xref: EMBL:AAA97458.1 xref: UniProtKB:Q13400 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011620 ! PMS2L8_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025465 name: Q7Z3Q2_HUMAN def: "Putative uncharacterized protein DKFZp686J1569" [UniProtKB:Q7Z3Q2] xref: EMBL:CAD97782.1 xref: UniProtKB:Q7Z3Q2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011972 ! DKFZp686J1569_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025467 name: Q6DHX9_HUMAN def: "LOC441259 protein" [UniProtKB:Q6DHX9] xref: EMBL:AAH75816.1 xref: UniProtKB:Q6DHX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011946 ! LOC441259_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0025485 name: Q2A130_HUMAN def: "Autogenous vein graft remodeling associated protein 5" [UniProtKB:Q2A130] xref: EMBL:CAJ80724.1 xref: UniProtKB:Q2A130 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021110 ! AVGR5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0025523 name: UNK_HUMAN def: "RING finger protein unkempt homolog" [UniProtKB:Q9C0B0] synonym: "Zinc finger CCCH domain-containing protein 5" EXACT [UniProtKB:Q9C0B0] xref: EMBL:AAH53362.1 xref: EMBL:BAB21844.1 xref: UniProtKB:Q9C0B0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022766 ! UNK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019109 ! atxn1-zc3h5 physical interaction relationship: transforms_into CCO:B0071736 ! UNK_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0071737 ! UNK_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0071738 ! UNK_HUMAN-Phosphotyrosine412 [Term] id: CCO:B0025531 name: A2A2V4_HUMAN def: "Vascular endothelial growth factor" [UniProtKB:A2A2V4] xref: EMBL:CAM28207.1 xref: UniProtKB:A2A2V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005897 ! VEGF_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0025635 name: PTPA_HUMAN def: "Serine/threonine-protein phosphatase 2A regulatory subunit B'" [UniProtKB:Q15257] synonym: "Phosphotyrosyl phosphatase activator" EXACT [UniProtKB:Q15257] synonym: "PP2A, subunit B', PR53 isoform" EXACT [UniProtKB:Q15257] synonym: "PTPA" EXACT [UniProtKB:Q15257] xref: EMBL:AAH02545.1 xref: EMBL:AAH11605.1 xref: EMBL:AAV38922.1 xref: EMBL:BAD96508.1 xref: EMBL:CAA51873.1 xref: EMBL:CAA60163.1 xref: EMBL:CAB77601.1 xref: EMBL:CAB77602.1 xref: EMBL:CAB77603.1 xref: EMBL:CAI12874.1 xref: UniProtKB:Q15257 xref: UniProtKB:Q15258 xref: UniProtKB:Q53GZ3 xref: UniProtKB:Q5TZQ2 xref: UniProtKB:Q9BUK1 xref: UniProtKB:Q9NNZ7 xref: UniProtKB:Q9NNZ8 xref: UniProtKB:Q9NNZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011641 ! PPP2R4_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001754 ! protein tyrosine phosphatase activator activity relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004134 ! phosphatase activator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008162 ! protein phosphatase 2A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0002020 ! positive regulation of protein amino acid dephosphorylation relationship: participates_in CCO:P0002021 ! negative regulation of protein amino acid dephosphorylation [Term] id: CCO:B0025709 name: ERG19_HUMAN def: "Diphosphomevalonate decarboxylase" [UniProtKB:P53602] synonym: "EC 4.1.1.33" EXACT [UniProtKB:P53602] synonym: "Mevalonate (diphospho)decarboxylase" EXACT [UniProtKB:P53602] synonym: "Mevalonate pyrophosphate decarboxylase" EXACT [UniProtKB:P53602] xref: EMBL:AAC50440.1 xref: EMBL:AAH00011.1 xref: EMBL:AAP35576.1 xref: EMBL:EAW66792.1 xref: UniProtKB:P53602 xref: UniProtKB:Q53Y65 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022225 ! MVD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020324 ! gnb5-mvd physical interaction relationship: participates_in CCO:I0020548 ! eif4ebp1-mvd physical interaction relationship: transforms_into CCO:B0066025 ! ERG19_HUMAN-Phosphoserine96 [Term] id: CCO:B0025768 name: LUC7L_HUMAN def: "Putative RNA-binding protein Luc7-like 1" [UniProtKB:Q9NQ29] synonym: "Putative SR protein LUC7B1" EXACT [UniProtKB:Q9NQ29] synonym: "SR+89" EXACT [UniProtKB:Q9NQ29] xref: EMBL:AAG22846.1 xref: EMBL:AAH03194.1 xref: EMBL:AAH65198.1 xref: EMBL:AAK61218.1 xref: EMBL:BAA91500.1 xref: EMBL:CAB93981.1 xref: EMBL:CAB93982.1 xref: UniProtKB:Q96S32 xref: UniProtKB:Q9NPH4 xref: UniProtKB:Q9NQ29 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013584 ! LUC7L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016034 ! tcerg1-luc7l physical interaction relationship: participates_in CCO:I0016042 ! gadd45g-luc7l physical interaction relationship: transforms_into CCO:B0043316 ! LUC7L_HUMAN-Phosphoserine363 [Term] id: CCO:B0025802 name: RAC2_HUMAN def: "Ras-related C3 botulinum toxin substrate 2 precursor" [UniProtKB:P15153] synonym: "GX" EXACT [UniProtKB:P15153] synonym: "p21-Rac2" EXACT [UniProtKB:P15153] synonym: "Small G protein" EXACT [UniProtKB:P15153] xref: EMBL:AAA35941.1 xref: EMBL:AAA36538.1 xref: EMBL:AAH01485.1 xref: EMBL:AAM21112.1 xref: EMBL:AAP35565.1 xref: EMBL:CAB45265.1 xref: EMBL:CAG30441.1 xref: UniProtKB:P15153 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019612 ! RAC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016244 ! rac2-ncf2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000922 ! regulation of hydrogen peroxide metabolic process relationship: transforms_into CCO:B0069702 ! RAC2_HUMAN-ADP-ribosylasparagine39 relationship: transforms_into CCO:B0069703 ! RAC2_HUMAN-Cysteine methyl ester189 [Term] id: CCO:B0025814 name: RAC3_HUMAN def: "Ras-related C3 botulinum toxin substrate 3 precursor" [UniProtKB:P60763] synonym: "p21-Rac3" EXACT [UniProtKB:P60763] xref: EMBL:AAC51667.1 xref: EMBL:AAH09605.1 xref: EMBL:AAH15197.1 xref: EMBL:AAM21113.1 xref: EMBL:AAV38250.1 xref: UniProtKB:O14658 xref: UniProtKB:P60763 xref: UniProtKB:Q5U0M8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019613 ! RAC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015963 ! nrbp-rac3-2 physical interaction relationship: participates_in CCO:I0019283 ! nrbp-rac3-3 physical interaction relationship: participates_in CCO:I0019506 ! nrbp-rac3-1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069704 ! RAC3_HUMAN-Phosphothreonine167 relationship: transforms_into CCO:B0069705 ! RAC3_HUMAN-Cysteine methyl ester189 [Term] id: CCO:B0025823 name: TOB1_HUMAN def: "Protein Tob1" [UniProtKB:P50616] synonym: "Transducer of erbB-2 1" EXACT [UniProtKB:P50616] xref: EMBL:AAH31406.1 xref: EMBL:AAH70493.1 xref: EMBL:AAH98415.1 xref: EMBL:AAV38187.1 xref: EMBL:AAV38188.1 xref: EMBL:BAA07423.1 xref: EMBL:CAG38726.1 xref: EMBL:CAG46487.1 xref: UniProtKB:P50616 xref: UniProtKB:Q4KMQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020323 ! TOB1_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020485 ! tob1-scmh1 physical interaction relationship: participates_in CCO:I0020486 ! tob1-setdb1 physical interaction relationship: participates_in CCO:P0000724 ! SMAD protein nuclear translocation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway relationship: participates_in CCO:P0002482 ! negative regulation of osteoblast differentiation [Term] id: CCO:B0025847 name: PTPRN_HUMAN def: "Receptor-type tyrosine-protein phosphatase-like N precursor" [UniProtKB:Q16849] synonym: "ICA 512" EXACT [UniProtKB:Q16849] synonym: "Islet cell antigen 512" EXACT [UniProtKB:Q16849] synonym: "Islet cell autoantigen 3" EXACT [UniProtKB:Q16849] synonym: "PTP IA-2" EXACT [UniProtKB:Q16849] synonym: "R-PTP-N" EXACT [UniProtKB:Q16849] xref: EMBL:AAA90974.1 xref: EMBL:CAA44688.2 xref: UniProtKB:Q08319 xref: UniProtKB:Q16849 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008038 ! PTPRN_human relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015961 ! ptprn-ptprt-2 physical interaction relationship: participates_in CCO:I0016312 ! ptprn-ptprt-3 physical interaction relationship: participates_in CCO:I0017763 ! ptprn-ptprt-1 physical interaction [Term] id: CCO:B0025860 name: ODPA_HUMAN def: "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor" [UniProtKB:P08559] synonym: "EC 1.2.4.1" EXACT [UniProtKB:P08559] synonym: "PDHE1-A type I" EXACT [UniProtKB:P08559] xref: EMBL:AAA36533.1 xref: EMBL:AAA60050.1 xref: EMBL:AAA60051.1 xref: EMBL:AAA60055.1 xref: EMBL:AAA60227.1 xref: EMBL:AAB59581.1 xref: EMBL:AAD23841.1 xref: EMBL:AAD23842.1 xref: EMBL:AAD23843.1 xref: EMBL:AAD23844.1 xref: EMBL:AAD23845.1 xref: EMBL:AAD23846.1 xref: EMBL:AAD23847.1 xref: EMBL:AAD23848.1 xref: EMBL:AAD23849.1 xref: EMBL:AAD23850.1 xref: EMBL:AAD23851.1 xref: EMBL:AAD23852.1 xref: EMBL:AAD23853.1 xref: EMBL:AAD23854.1 xref: EMBL:AAD23855.1 xref: EMBL:AAD23856.1 xref: EMBL:AAD23857.1 xref: EMBL:AAD23858.1 xref: EMBL:AAD23859.1 xref: EMBL:AAD23860.1 xref: EMBL:AAD23861.1 xref: EMBL:AAD23862.1 xref: EMBL:AAD23863.1 xref: EMBL:AAD23864.1 xref: EMBL:AAD23866.1 xref: EMBL:AAD23867.1 xref: EMBL:AAD23868.1 xref: EMBL:AAD23869.1 xref: EMBL:AAD23870.1 xref: EMBL:AAD23871.1 xref: EMBL:AAD23872.1 xref: EMBL:AAD23873.1 xref: EMBL:AAD23874.1 xref: EMBL:AAD23875.1 xref: EMBL:AAD23876.1 xref: EMBL:AAH02406.1 xref: EMBL:BAA14121.1 xref: EMBL:CAA36933.1 xref: EMBL:CAA36934.1 xref: UniProtKB:P08559 xref: UniProtKB:Q9NP12 xref: UniProtKB:Q9UBJ8 xref: UniProtKB:Q9UBU0 xref: UniProtKB:Q9UNG4 xref: UniProtKB:Q9UNG5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022474 ! PDHA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020044 ! itgb3bp-pdha1 physical interaction relationship: transforms_into CCO:B0068956 ! ODPA_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0068957 ! ODPA_HUMAN-Phosphotyrosine289 relationship: transforms_into CCO:B0068958 ! ODPA_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0068959 ! ODPA_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0068960 ! ODPA_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0068961 ! ODPA_HUMAN-Phosphotyrosine301 [Term] id: CCO:B0025951 name: LRP5_HUMAN def: "Low-density lipoprotein receptor-related protein 5 precursor" [UniProtKB:O75197] xref: EMBL:AAC36467.1 xref: EMBL:AAK52433.1 xref: EMBL:BAA33051.1 xref: UniProtKB:O75197 xref: UniProtKB:Q96TD6 xref: UniProtKB:Q9UP66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007797 ! LRP5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0025953 name: LRP1_HUMAN def: "Prolow-density lipoprotein receptor-related protein 1 precursor" [UniProtKB:Q07954] synonym: "A2MR" EXACT [UniProtKB:Q07954] synonym: "Alpha-2-macroglobulin receptor" EXACT [UniProtKB:Q07954] synonym: "APOER" EXACT [UniProtKB:Q07954] synonym: "Apolipoprotein E receptor" EXACT [UniProtKB:Q07954] synonym: "CD91 antigen" EXACT [UniProtKB:Q07954] synonym: "LRP" EXACT [UniProtKB:Q07954] xref: EMBL:AAC64265.1 xref: EMBL:ABC40732.1 xref: EMBL:CAA32112.1 xref: EMBL:CAA33464.1 xref: EMBL:CAD57169.1 xref: UniProtKB:Q07954 xref: UniProtKB:Q2PP12 xref: UniProtKB:Q8IVG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007794 ! LRP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0035122 ! LRP1_HUMAN-Phosphothreonine4460 relationship: transforms_into CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: transforms_into CCO:B0035124 ! LRP1_HUMAN-Phosphoserine4517 relationship: transforms_into CCO:B0035125 ! LRP1_HUMAN-Phosphoserine4520 relationship: transforms_into CCO:B0035126 ! LRP1_HUMAN-Phosphoserine4523 [Term] id: CCO:B0025967 name: LRP6_HUMAN def: "Low-density lipoprotein receptor-related protein 6 precursor" [UniProtKB:O75581] xref: EMBL:AAC33006.1 xref: EMBL:AAI17137.1 xref: EMBL:AAI26406.1 xref: UniProtKB:O75581 xref: UniProtKB:Q17RZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007798 ! LRP6_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001362 ! low-density lipoprotein receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016146 ! lrp6-tem8 physical interaction relationship: participates_in CCO:I0016147 ! lrp6-tem8-1 physical interaction relationship: participates_in CCO:I0016148 ! lrp6-tem8-2 physical interaction relationship: participates_in CCO:I0016149 ! lrp6-cmg2 physical interaction relationship: participates_in CCO:I0017909 ! lrp6-cmg2-1 colocalization relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0025990 name: 2A5B_HUMAN def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform" [UniProtKB:Q15173] synonym: "PP2A, B subunit, B' beta isoform" EXACT [UniProtKB:Q15173] synonym: "PP2A, B subunit, B56 beta isoform" EXACT [UniProtKB:Q15173] synonym: "PP2A, B subunit, PR61 beta isoform" EXACT [UniProtKB:Q15173] synonym: "PP2A, B subunit, R5 beta isoform" EXACT [UniProtKB:Q15173] xref: EMBL:AAC37602.1 xref: EMBL:AAH45619.1 xref: EMBL:CAA93152.1 xref: UniProtKB:Q13853 xref: UniProtKB:Q15173 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007184 ! PPP2R5B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0025993 name: Q59EK0_HUMAN def: "Epsilon isoform of regulatory subunit B56, protein phosphatase 2A variant" [UniProtKB:Q59EK0] xref: EMBL:BAD93048.1 xref: UniProtKB:Q59EK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0025995 name: Q96B13_HUMAN def: "Protein phosphatase 2, regulatory subunit B', gamma isoform" [UniProtKB:Q96B13] xref: EMBL:AAH16183.1 xref: UniProtKB:Q96B13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007185 ! PPP2R5C_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0025996 name: Q6ZN33_HUMAN def: "cDNA FLJ16473 fis, clone BRHIP3026052, highly similar to Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, gamma isoform" [UniProtKB:Q6ZN33] xref: EMBL:BAD18542.1 xref: UniProtKB:Q6ZN33 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026004 name: 2A5G_HUMAN def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform" [UniProtKB:Q13362] synonym: "PP2A, B subunit, B' gamma isoform" EXACT [UniProtKB:Q13362] synonym: "PP2A, B subunit, B56 gamma isoform" EXACT [UniProtKB:Q13362] synonym: "PP2A, B subunit, PR61 gamma isoform" EXACT [UniProtKB:Q13362] synonym: "PP2A, B subunit, R5 gamma isoform" EXACT [UniProtKB:Q13362] synonym: "Renal carcinoma antigen NY-REN-29" EXACT [UniProtKB:Q13362] xref: EMBL:AAC37603.1 xref: EMBL:AAC50387.1 xref: EMBL:BAA05465.1 xref: EMBL:CAA93154.1 xref: UniProtKB:Q13362 xref: UniProtKB:Q14391 xref: UniProtKB:Q15060 xref: UniProtKB:Q15174 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007185 ! PPP2R5C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0052260 ! 2A5G_HUMAN-Phosphotyrosine348 relationship: transforms_into CCO:B0052261 ! 2A5G_HUMAN-Phosphotyrosine349 relationship: transforms_into CCO:B0052262 ! 2A5G_HUMAN-Phosphotyrosine354 [Term] id: CCO:B0026021 name: RAB1B_HUMAN def: "Ras-related protein Rab-1B" [UniProtKB:Q9H0U4] xref: EMBL:AAH71169.1 xref: EMBL:AAP97212.1 xref: EMBL:CAB66570.1 xref: UniProtKB:Q9H0U4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019577 ! RAB1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069673 ! RAB1B_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0026033 name: SPCS_HUMAN def: "O-phosphoseryl-tRNA(Sec) selenium transferase" [UniProtKB:Q9HD40] synonym: "EC 2.9.1.n1" EXACT [UniProtKB:Q9HD40] synonym: "Liver-pancreas antigen" EXACT [UniProtKB:Q9HD40] synonym: "LP" EXACT [UniProtKB:Q9HD40] synonym: "Sec synthase" EXACT [UniProtKB:Q9HD40] synonym: "Selenocysteine synthase" EXACT [UniProtKB:Q9HD40] synonym: "Selenocysteinyl-tRNA(Sec) synthase" EXACT [UniProtKB:Q9HD40] synonym: "Sep-tRNA:Sec-tRNA synthase" EXACT [UniProtKB:Q9HD40] synonym: "SepSecS" EXACT [UniProtKB:Q9HD40] synonym: "SLA" EXACT [UniProtKB:Q9HD40] synonym: "SLA-p35" EXACT [UniProtKB:Q9HD40] synonym: "SLA/LP autoantigen" EXACT [UniProtKB:Q9HD40] synonym: "Soluble liver antigen" EXACT [UniProtKB:Q9HD40] synonym: "tRNA(Ser/Sec)-associated antigenic protein" EXACT [UniProtKB:Q9HD40] synonym: "UGA suppressor tRNA-associated protein" EXACT [UniProtKB:Q9HD40] xref: EMBL:AAD33963.2 xref: EMBL:AAG00491.1 xref: EMBL:CAB62209.1 xref: EMBL:CAB89517.1 xref: UniProtKB:Q9HD40 xref: UniProtKB:Q9NXZ5 xref: UniProtKB:Q9UGM9 xref: UniProtKB:Q9Y353 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020009 ! SEPSECS_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001897 ! selenium binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000465 ! selenocysteine incorporation [Term] id: CCO:B0026103 name: SORCN_HUMAN def: "Sorcin" [UniProtKB:P30626] synonym: "22 kDa protein" EXACT [UniProtKB:P30626] synonym: "CP-22" EXACT [UniProtKB:P30626] synonym: "V19" EXACT [UniProtKB:P30626] xref: EMBL:AAA60588.1 xref: EMBL:AAA92155.1 xref: EMBL:AAH11025.1 xref: UniProtKB:P30626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008198 ! SRI_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001514 ! calcium channel regulator activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0015596 ! ndp52-sri physical interaction relationship: participates_in CCO:I0015854 ! sri-sri physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026105 name: GRAN_HUMAN def: "Grancalcin" [UniProtKB:P28676] xref: EMBL:AAA58498.1 xref: EMBL:AAH05214.1 xref: EMBL:AAX93138.1 xref: EMBL:BAD93005.1 xref: UniProtKB:P28676 xref: UniProtKB:Q53TB5 xref: UniProtKB:Q59EP3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007606 ! GCA_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0019040 ! atxn1-gca physical interaction [Term] id: CCO:B0026108 name: CUTC_HUMAN def: "Copper homeostasis protein cutC homolog" [UniProtKB:Q9NTM9] xref: EMBL:AAD27741.1 xref: EMBL:AAH21105.1 xref: EMBL:AAH28948.1 xref: UniProtKB:Q9NTM9 xref: UniProtKB:Q9Y321 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006037 ! CUTC_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020241 ! ascc2-cutc physical interaction [Term] id: CCO:B0026109 name: Q8NEC4_HUMAN def: "PPP2R2C protein" [UniProtKB:Q8NEC4] synonym: "Protein phosphatase 2 (Formerly 2A), regulatory subunit B (PR 52), gamma isoform, isoform CRA_b" EXACT [UniProtKB:Q8NEC4] xref: EMBL:AAH32954.1 xref: EMBL:EAW82394.1 xref: UniProtKB:Q8NEC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007189 ! PPP2R2C_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026111 name: 2ABD_HUMAN def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform" [UniProtKB:Q66LE6] synonym: "PP2A, subunit B, B-delta isoform" EXACT [UniProtKB:Q66LE6] synonym: "PP2A, subunit B, B55-delta isoform" EXACT [UniProtKB:Q66LE6] synonym: "PP2A, subunit B, PR55-delta isoform" EXACT [UniProtKB:Q66LE6] synonym: "PP2A, subunit B, R2-delta isoform" EXACT [UniProtKB:Q66LE6] xref: EMBL:AAH47379.1 xref: EMBL:BAA96065.1 xref: EMBL:CAI16703.1 xref: UniProtKB:Q5SQJ2 xref: UniProtKB:Q66LE6 xref: UniProtKB:Q9P1Y7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007188 ! PPP2R2D_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026113 name: Q59GC6_HUMAN def: "Gamma isoform of regulatory subunit B55, protein phosphatase 2 isoform b variant" [UniProtKB:Q59GC6] xref: EMBL:BAD92420.1 xref: UniProtKB:Q59GC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026114 name: 2ABA_HUMAN def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform" [UniProtKB:P63151] synonym: "PP2A, subunit B, B-alpha isoform" EXACT [UniProtKB:P63151] synonym: "PP2A, subunit B, B55-alpha isoform" EXACT [UniProtKB:P63151] synonym: "PP2A, subunit B, PR55-alpha isoform" EXACT [UniProtKB:P63151] synonym: "PP2A, subunit B, R2-alpha isoform" EXACT [UniProtKB:P63151] xref: EMBL:AAA36490.1 xref: EMBL:AAH41071.1 xref: UniProtKB:P50409 xref: UniProtKB:P63151 xref: UniProtKB:Q00007 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007186 ! PPP2R2A_human relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:I0007181 ! snf1l2-2aab-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026115 name: Q56VW8_HUMAN def: "Lung cancer-related protein 9" [UniProtKB:Q56VW8] xref: EMBL:AAO85219.1 xref: UniProtKB:Q56VW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026116 name: 2ABB_HUMAN def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform" [UniProtKB:Q00005] synonym: "PP2A, subunit B, B-beta isoform" EXACT [UniProtKB:Q00005] synonym: "PP2A, subunit B, B55-beta isoform" EXACT [UniProtKB:Q00005] synonym: "PP2A, subunit B, PR55-beta isoform" EXACT [UniProtKB:Q00005] synonym: "PP2A, subunit B, R2-beta isoform" EXACT [UniProtKB:Q00005] xref: EMBL:AAA36493.1 xref: EMBL:AAH31790.1 xref: UniProtKB:Q00005 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007187 ! PPP2R2B_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026117 name: Q6ZP32_HUMAN def: "CDNA FLJ26613 fis, clone MPB05565, highly similar to Serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, alpha isoform" [UniProtKB:Q6ZP32] xref: EMBL:BAC85293.1 xref: UniProtKB:Q6ZP32 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026121 name: 2ABG_HUMAN def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform" [UniProtKB:Q9Y2T4] synonym: "IMYPNO1" EXACT [UniProtKB:Q9Y2T4] synonym: "PP2A, subunit B, B-gamma isoform" EXACT [UniProtKB:Q9Y2T4] synonym: "PP2A, subunit B, B55-gamma isoform" EXACT [UniProtKB:Q9Y2T4] synonym: "PP2A, subunit B, PR55-gamma isoform" EXACT [UniProtKB:Q9Y2T4] synonym: "PP2A, subunit B, R2-gamma isoform" EXACT [UniProtKB:Q9Y2T4] xref: EMBL:AAD20987.1 xref: EMBL:AAG39636.1 xref: UniProtKB:Q9H3G7 xref: UniProtKB:Q9Y2T4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007189 ! PPP2R2C_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026125 name: A6NEJ2_HUMAN def: "Putative uncharacterized protein PPP2R2B" [UniProtKB:A6NEJ2] xref: UniProtKB:A6NEJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007187 ! PPP2R2B_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026163 name: LANC2_HUMAN def: "LanC-like protein 2" [UniProtKB:Q9NS86] synonym: "Testis-specific adriamycin sensitivity protein" EXACT [UniProtKB:Q9NS86] xref: EMBL:AAH04887.2 xref: EMBL:AAK83286.1 xref: EMBL:AAQ93360.1 xref: EMBL:BAA96800.1 xref: EMBL:CAC21715.1 xref: EMBL:CAD28471.1 xref: UniProtKB:Q8TCQ3 xref: UniProtKB:Q9BSR1 xref: UniProtKB:Q9NS86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007772 ! LANCL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0035085 ! LANC2_HUMAN-Phosphotyrosine198 relationship: transforms_into CCO:B0035086 ! LANC2_HUMAN-Phosphotyrosine259 relationship: transforms_into CCO:B0035087 ! LANC2_HUMAN-Phosphotyrosine295 [Term] id: CCO:B0026166 name: LANC1_HUMAN def: "LanC-like protein 1" [UniProtKB:O43813] synonym: "40 kDa erythrocyte membrane protein" EXACT [UniProtKB:O43813] synonym: "p40" EXACT [UniProtKB:O43813] xref: EMBL:AAH28685.1 xref: EMBL:CAA72205.1 xref: EMBL:CAC21950.1 xref: UniProtKB:O43813 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007771 ! LANCL1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0026171 name: KI18A_HUMAN def: "Kinesin-like protein KIF18A" [UniProtKB:Q8NI77] synonym: "Marrow stromal KIF18A" EXACT [UniProtKB:Q8NI77] synonym: "MS-KIF18A" EXACT [UniProtKB:Q8NI77] xref: EMBL:AAH48347.1 xref: EMBL:AAX16185.1 xref: EMBL:BAB93508.1 xref: EMBL:CAB66753.1 xref: UniProtKB:Q4VPE3 xref: UniProtKB:Q86VS5 xref: UniProtKB:Q8NI77 xref: UniProtKB:Q9H0F3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007746 ! KIF18A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016411 ! nfkbib-ok/sw_cl_108 physical interaction relationship: transforms_into CCO:B0035018 ! KI18A_HUMAN-Phosphothreonine706 relationship: transforms_into CCO:B0039483 ! KI18A_HUMAN-Phosphoserine357 [Term] id: CCO:B0026181 name: SF3B3_HUMAN def: "Splicing factor 3B subunit 3" [UniProtKB:Q15393] synonym: "Pre-mRNA-splicing factor SF3b 130 kDa subunit" EXACT [UniProtKB:Q15393] synonym: "SAP 130" EXACT [UniProtKB:Q15393] synonym: "SF3b130" EXACT [UniProtKB:Q15393] synonym: "Spliceosome-associated protein 130" EXACT [UniProtKB:Q15393] synonym: "STAF130" EXACT [UniProtKB:Q15393] xref: EMBL:AAH00463.1 xref: EMBL:AAH03146.1 xref: EMBL:AAH09780.1 xref: EMBL:AAH68974.1 xref: EMBL:BAA02805.1 xref: EMBL:BAA32662.2 xref: EMBL:CAB53699.1 xref: EMBL:CAB56791.1 xref: UniProtKB:Q15393 xref: UniProtKB:Q6NTI8 xref: UniProtKB:Q96GC0 xref: UniProtKB:Q9BPY2 xref: UniProtKB:Q9UFX7 xref: UniProtKB:Q9UJ29 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008176 ! SF3B3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: participates_in CCO:I0020601 ! mpp3-sf3b3 physical interaction [Term] id: CCO:B0026184 name: RFC3_HUMAN def: "Replication factor C subunit 3" [UniProtKB:P40938] synonym: "A1 38 kDa subunit" EXACT [UniProtKB:P40938] synonym: "Activator 1 38 kDa subunit" EXACT [UniProtKB:P40938] synonym: "Activator 1 subunit 3" EXACT [UniProtKB:P40938] synonym: "Replication factor C 38 kDa subunit" EXACT [UniProtKB:P40938] synonym: "RF-C 38 kDa subunit" EXACT [UniProtKB:P40938] synonym: "RFC38" EXACT [UniProtKB:P40938] xref: EMBL:AAB07268.1 xref: EMBL:AAH00149.1 xref: EMBL:AAL82505.1 xref: UniProtKB:O15252 xref: UniProtKB:P40938 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008078 ! RFC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015869 ! rfc1-rfc2-2 physical interaction relationship: participates_in CCO:I0015870 ! rfc1-rfc2-3 physical interaction relationship: participates_in CCO:I0015871 ! rfc1-rfc2-4 physical interaction relationship: participates_in CCO:I0015872 ! rfc2-rfc3-1 physical interaction relationship: participates_in CCO:I0015874 ! rfc4-rfc3-2 physical interaction relationship: participates_in CCO:I0015875 ! rfc1-rfc3-1 physical interaction relationship: participates_in CCO:I0015876 ! rfc4-rfc3-3 physical interaction relationship: participates_in CCO:I0015877 ! rfc3-rfc4-1 physical interaction relationship: participates_in CCO:I0017805 ! rfc2-rfc3-3 physical interaction relationship: participates_in CCO:I0019330 ! rfc_human physical interaction relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000635 ! DNA strand elongation during DNA replication relationship: transforms_into CCO:B0035541 ! RFC3_HUMAN-Phosphoserine125 [Term] id: CCO:B0026210 name: Q59FA8_HUMAN def: "Integrin alpha-IIb variant" [UniProtKB:Q59FA8] xref: EMBL:BAD92789.1 xref: UniProtKB:Q59FA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0026213 name: ITA8_HUMAN def: "Integrin alpha-8 precursor" [UniProtKB:P53708] xref: EMBL:AAA93514.1 xref: EMBL:AAQ56848.2 xref: EMBL:CAH73424.1 xref: EMBL:CAI14955.1 xref: UniProtKB:P53708 xref: UniProtKB:Q5VX94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018338 ! ITGA8_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0001272 ! positive regulation of transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0026215 name: ITA2B_HUMAN def: "Integrin alpha-IIb precursor" [UniProtKB:P08514] synonym: "CD41 antigen" EXACT [UniProtKB:P08514] synonym: "GPalpha IIb" EXACT [UniProtKB:P08514] synonym: "GPIIb" EXACT [UniProtKB:P08514] synonym: "Platelet membrane glycoprotein IIb" EXACT [UniProtKB:P08514] xref: EMBL:AAA35926.1 xref: EMBL:AAA52587.1 xref: EMBL:AAA52588.1 xref: EMBL:AAA52597.1 xref: EMBL:AAA52599.1 xref: EMBL:AAA53150.1 xref: EMBL:AAA60114.1 xref: EMBL:AAC98507.1 xref: EMBL:CAA29987.1 xref: UniProtKB:O95366 xref: UniProtKB:P08514 xref: UniProtKB:Q14443 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018332 ! ITGA2B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001129 ! platelet alpha granule membrane relationship: participates_in CCO:I0016292 ! itga2b-itga2b-6 physical interaction relationship: participates_in CCO:I0016297 ! itga2b-itga2b-7 physical interaction relationship: participates_in CCO:I0016303 ! itga2b-itgb3-1 physical interaction relationship: participates_in CCO:I0016308 ! itgb3-itga2b-1 physical interaction relationship: participates_in CCO:I0017271 ! itga2b-itgb3-2 direct interaction relationship: participates_in CCO:I0017512 ! itga2b-itga2b-2 direct interaction relationship: participates_in CCO:I0017513 ! itga2b-itga2b-5 direct interaction relationship: participates_in CCO:I0018073 ! itga2b-itga2b-1 physical interaction relationship: participates_in CCO:I0018522 ! itga2b-itga2b-3 direct interaction relationship: participates_in CCO:I0019265 ! itga2b-itga2b-4 direct interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0067158 ! ITA2B_HUMAN-acid891 [Term] id: CCO:B0026216 name: Q17R67_HUMAN def: "Integrin, alpha 2b (Platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)" [UniProtKB:Q17R67] xref: EMBL:AAI17444.1 xref: EMBL:AAI26443.1 xref: UniProtKB:Q17R67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018332 ! ITGA2B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0026217 name: ITA5_HUMAN def: "Integrin alpha-5 precursor" [UniProtKB:P08648] synonym: "CD49 antigen-like family member E" EXACT [UniProtKB:P08648] synonym: "CD49e antigen" EXACT [UniProtKB:P08648] synonym: "Fibronectin receptor subunit alpha" EXACT [UniProtKB:P08648] synonym: "Integrin alpha-F" EXACT [UniProtKB:P08648] synonym: "VLA-5" EXACT [UniProtKB:P08648] xref: EMBL:AAA52467.1 xref: EMBL:AAH08786.1 xref: EMBL:CAA29601.1 xref: UniProtKB:P08648 xref: UniProtKB:Q96HA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018335 ! ITGA5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0026218 name: ITAV_HUMAN def: "Integrin alpha-V precursor" [UniProtKB:P06756] synonym: "CD51 antigen" EXACT [UniProtKB:P06756] synonym: "Vitronectin receptor subunit alpha" EXACT [UniProtKB:P06756] xref: EMBL:AAA36808.1 xref: EMBL:AAA61631.1 xref: EMBL:AAG03000.1 xref: EMBL:AAI26232.1 xref: EMBL:AAY24257.1 xref: EMBL:BAD93131.1 xref: UniProtKB:A0AV67 xref: UniProtKB:P06756 xref: UniProtKB:Q53SK4 xref: UniProtKB:Q59EB7 xref: UniProtKB:Q6LD15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018340 ! ITGAV_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016012 ! itgav-angptl3-1 physical interaction relationship: participates_in CCO:I0016203 ! itgav-itgb3-3 direct interaction relationship: participates_in CCO:I0017784 ! itgav-itgb3-1 direct interaction relationship: participates_in CCO:I0017792 ! itgav-itgb3-2 direct interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0026247 name: A2NWD3_HUMAN def: "Platelet-derived growth factor-BB" [UniProtKB:A2NWD3] xref: EMBL:CAA45383.1 xref: UniProtKB:A2NWD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0026248 name: ERCC2_HUMAN def: "TFIIH basal transcription factor complex helicase subunit" [UniProtKB:P18074] synonym: "CXPD" EXACT [UniProtKB:P18074] synonym: "DNA excision repair protein ERCC-2" EXACT [UniProtKB:P18074] synonym: "DNA repair protein complementing XP-D cells" EXACT [UniProtKB:P18074] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P18074] synonym: "Xeroderma pigmentosum group D-complementing protein" EXACT [UniProtKB:P18074] xref: EMBL:AAI08256.1 xref: EMBL:AAL48323.1 xref: EMBL:AAM45142.1 xref: EMBL:CAA36463.1 xref: EMBL:CAA36464.1 xref: UniProtKB:P18074 xref: UniProtKB:Q2YDY2 xref: UniProtKB:Q8N721 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006358 ! ERCC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0005801 ! 5'-3' DNA helicase activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000279 ! holo TFIIH complex relationship: located_in CCO:C0000901 ! cyclin-dependent protein kinase activating kinase holoenzyme complex relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0026249 name: ZMY11_HUMAN def: "Zinc finger MYND domain-containing protein 11" [UniProtKB:Q15326] synonym: "Adenovirus 5 E1A-binding protein" EXACT [UniProtKB:Q15326] synonym: "Protein BS69" EXACT [UniProtKB:Q15326] xref: EMBL:CAA60052.1 xref: EMBL:CAH69845.1 xref: EMBL:CAI40899.1 xref: UniProtKB:Q15326 xref: UniProtKB:Q5VUI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006374 ! ZMYND11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0026393 ! ZMY11_HUMAN-Phosphoserine381 [Term] id: CCO:B0026250 name: Q5JXL7_HUMAN def: "Putative uncharacterized protein DKFZp586I031" [UniProtKB:Q5JXL7] xref: EMBL:CAI46224.1 xref: UniProtKB:Q5JXL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006376 ! DKFZp586I031_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0026252 name: NOXIN_HUMAN def: "Nitric oxide-inducible gene protein" [UniProtKB:Q8IXT1] xref: EMBL:AAH39268.1 xref: EMBL:BAB14764.1 xref: EMBL:BAB71685.1 xref: UniProtKB:Q8IXT1 xref: UniProtKB:Q96LK6 xref: UniProtKB:Q9H856 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006364 ! NOXIN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0026253 name: SEP12_HUMAN def: "Septin-12" [UniProtKB:Q8IYM1] xref: EMBL:AAH24017.1 xref: EMBL:AAH35619.1 xref: EMBL:ABE68946.1 xref: EMBL:ABF61438.1 xref: EMBL:ABR10901.1 xref: EMBL:BAB71681.1 xref: EMBL:EAW85265.1 xref: UniProtKB:Q0P6B0 xref: UniProtKB:Q1PBH0 xref: UniProtKB:Q8IYM1 xref: UniProtKB:Q96LL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006020 ! SEPT12_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0026254 name: JUB_HUMAN def: "Protein ajuba" [UniProtKB:Q96IF1] xref: EMBL:AAH07580.1 xref: EMBL:AAH34968.1 xref: EMBL:AAO37641.1 xref: EMBL:EAW66204.1 xref: UniProtKB:Q96IF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006039 ! JUB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007689 ! gfi1b-jub physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: transforms_into CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0026381 ! JUB_HUMAN-Phosphoserine263 [Term] id: CCO:B0026255 name: KLDC3_HUMAN def: "Kelch domain-containing protein 3" [UniProtKB:Q9BQ90] synonym: "Protein Peas" EXACT [UniProtKB:Q9BQ90] synonym: "Testis intracellular mediator protein" EXACT [UniProtKB:Q9BQ90] xref: EMBL:AAH00295.1 xref: EMBL:AAH01789.1 xref: EMBL:AAH01793.1 xref: EMBL:AAH07296.1 xref: EMBL:AAH21546.1 xref: EMBL:BAB63257.1 xref: EMBL:CAI19796.1 xref: UniProtKB:Q9BQ90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006363 ! KLHDC3_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000117 ! nuclear chromatin relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000122 ! meiotic recombination [Term] id: CCO:B0026256 name: RPRM_HUMAN def: "Protein reprimo" [UniProtKB:Q9NS64] xref: EMBL:AAH02908.1 xref: EMBL:AAY14783.1 xref: EMBL:BAB01513.1 xref: EMBL:EAX11467.1 xref: UniProtKB:Q9NS64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006052 ! RPRM_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0026257 name: PDS5B_HUMAN def: "Sister chromatid cohesion protein PDS5 homolog B" [UniProtKB:Q9NTI5] synonym: "Androgen-induced proliferation inhibitor" EXACT [UniProtKB:Q9NTI5] synonym: "Androgen-induced prostate proliferative shutoff-associated protein AS3" EXACT [UniProtKB:Q9NTI5] xref: EMBL:AAD22134.2 xref: EMBL:AAH39256.1 xref: EMBL:AAH70274.1 xref: EMBL:BAA76823.2 xref: EMBL:BAB15584.1 xref: EMBL:CAB69911.1 xref: EMBL:CAH73160.2 xref: EMBL:CAI10806.2 xref: UniProtKB:Q5R3S3 xref: UniProtKB:Q5W0K8 xref: UniProtKB:Q6NSC3 xref: UniProtKB:Q8IXT6 xref: UniProtKB:Q9H5N8 xref: UniProtKB:Q9NTI5 xref: UniProtKB:Q9Y2I5 xref: UniProtKB:Q9Y451 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006365 ! PDS5B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000078 ! mitotic sister chromatid cohesion relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0026385 ! PDS5B_HUMAN-Phosphoserine1166 relationship: transforms_into CCO:B0026386 ! PDS5B_HUMAN-Phosphoserine1257 relationship: transforms_into CCO:B0026387 ! PDS5B_HUMAN-Phosphoserine1259 relationship: transforms_into CCO:B0026388 ! PDS5B_HUMAN-Phosphoserine1358 relationship: transforms_into CCO:B0026389 ! PDS5B_HUMAN-Phosphothreonine1367 relationship: transforms_into CCO:B0026390 ! PDS5B_HUMAN-Phosphothreonine1370 relationship: transforms_into CCO:B0026391 ! PDS5B_HUMAN-Phosphoserine1383 relationship: transforms_into CCO:B0036021 ! PDS5B_HUMAN-Phosphoserine1379 relationship: transforms_into CCO:B0069190 ! PDS5B_HUMAN-Phosphoserine1283 relationship: transforms_into CCO:B0069191 ! PDS5B_HUMAN-Phosphoserine1319 relationship: transforms_into CCO:B0069192 ! PDS5B_HUMAN-Phosphoserine1334 [Term] id: CCO:B0026258 name: TCF19_HUMAN def: "Transcription factor 19" [UniProtKB:Q9Y242] synonym: "Transcription factor SC1" EXACT [UniProtKB:Q9Y242] xref: EMBL:AAB19475.2 xref: EMBL:AAB60363.1 xref: EMBL:AAH02493.1 xref: EMBL:AAH33086.1 xref: EMBL:AAH44632.1 xref: EMBL:AAP35911.1 xref: EMBL:BAA82324.1 xref: EMBL:BAA82325.1 xref: EMBL:BAA82326.1 xref: EMBL:BAA82327.1 xref: EMBL:BAB63312.1 xref: EMBL:BAC54945.1 xref: EMBL:BAE78629.1 xref: EMBL:BAF31280.1 xref: EMBL:CAI17406.1 xref: EMBL:CAI18329.1 xref: EMBL:CAI18484.1 xref: EMBL:CAI18707.1 xref: EMBL:EAX03363.1 xref: UniProtKB:A6NCT8 xref: UniProtKB:Q0EFA8 xref: UniProtKB:Q13176 xref: UniProtKB:Q15967 xref: UniProtKB:Q5SQ89 xref: UniProtKB:Q5STD6 xref: UniProtKB:Q5STF5 xref: UniProtKB:Q9BUM2 xref: UniProtKB:Q9UBH7 xref: UniProtKB:Q9Y242 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006372 ! TCF19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0026392 ! TCF19_HUMAN-Phosphoserine78 [Term] id: CCO:B0026267 name: DHB14_HUMAN def: "17-beta-hydroxysteroid dehydrogenase 14" [UniProtKB:Q9BPX1] synonym: "17-beta-hydroxysteroid dehydrogenase DHRS10" EXACT [UniProtKB:Q9BPX1] synonym: "Dehydrogenase/reductase SDR family member 10" EXACT [UniProtKB:Q9BPX1] synonym: "EC 1.1.1.-" EXACT [UniProtKB:Q9BPX1] synonym: "Retinal short-chain dehydrogenase/reductase retSDR3" EXACT [UniProtKB:Q9BPX1] xref: EMBL:AAF06940.1 xref: EMBL:AAH06283.1 xref: EMBL:AAH06294.1 xref: EMBL:AAQ88796.1 xref: UniProtKB:Q9BPX1 xref: UniProtKB:Q9UKU3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006348 ! HSD17B14_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000724 ! estradiol 17-beta-dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006358 ! testosterone 17-beta-dehydrogenase (NADP+) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0005744 ! ddit3-dhrs10 physical interaction [Term] id: CCO:B0026268 name: CACO2_HUMAN def: "Calcium-binding and coiled-coil domain-containing protein 2" [UniProtKB:Q13137] synonym: "Antigen nuclear dot 52 kDa protein" EXACT [UniProtKB:Q13137] synonym: "Nuclear domain 10 protein 52" EXACT [UniProtKB:Q13137] synonym: "Nuclear domain 10 protein NDP52" EXACT [UniProtKB:Q13137] synonym: "Nuclear dot protein 52" EXACT [UniProtKB:Q13137] xref: EMBL:AAA75297.1 xref: EMBL:AAH04130.1 xref: EMBL:AAH15893.1 xref: EMBL:BAD96386.1 xref: EMBL:BAD96947.1 xref: EMBL:CAG33044.1 xref: EMBL:EAW94707.1 xref: UniProtKB:Q13137 xref: UniProtKB:Q53FQ5 xref: UniProtKB:Q53HB5 xref: UniProtKB:Q6IBN9 xref: UniProtKB:Q9BTF7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006346 ! CALCOCO2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0005792 ! ndp52-shc1 physical interaction relationship: participates_in CCO:I0008678 ! ndp52-psma1 physical interaction relationship: participates_in CCO:I0015082 ! ndp52-pias4 physical interaction relationship: participates_in CCO:I0015288 ! ndp52-tcfl1 physical interaction relationship: participates_in CCO:I0015326 ! ndp52-znf451 physical interaction relationship: participates_in CCO:I0015436 ! ndp52-poli physical interaction relationship: participates_in CCO:I0015493 ! myst2-ndp52 physical interaction relationship: participates_in CCO:I0015535 ! ndp52-pcgf1 physical interaction relationship: participates_in CCO:I0015558 ! ndp52-smarcd1 physical interaction relationship: participates_in CCO:I0015561 ! ndp52-tceb3b physical interaction relationship: participates_in CCO:I0015586 ! ndp52-znf426 physical interaction relationship: participates_in CCO:I0015596 ! ndp52-sri physical interaction relationship: participates_in CCO:I0015629 ! ndp52-traf2 physical interaction relationship: participates_in CCO:I0015678 ! ndp52-znf408 physical interaction relationship: participates_in CCO:I0015726 ! ndp52-rhpn1 physical interaction relationship: participates_in CCO:I0015805 ! drr1-ndp52 physical interaction [Term] id: CCO:B0026269 name: EIF3G_HUMAN def: "Eukaryotic translation initiation factor 3 subunit G" [UniProtKB:O75821] synonym: "eIF-3 RNA-binding subunit" EXACT [UniProtKB:O75821] synonym: "eIF-3-delta" EXACT [UniProtKB:O75821] synonym: "eIF3 p42" EXACT [UniProtKB:O75821] synonym: "eIF3 p44" EXACT [UniProtKB:O75821] synonym: "eIF3g" EXACT [UniProtKB:O75821] synonym: "Eukaryotic translation initiation factor 3 subunit 4" EXACT [UniProtKB:O75821] xref: EMBL:AAB71866.1 xref: EMBL:AAC78728.1 xref: EMBL:AAG15396.1 xref: EMBL:AAG15419.1 xref: EMBL:AAH00733.1 xref: EMBL:AAH08469.1 xref: EMBL:AAP35535.1 xref: UniProtKB:O14801 xref: UniProtKB:O75821 xref: UniProtKB:Q969U5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006354 ! EIF3G_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006485 ! mphosph6-eif3s4 physical interaction relationship: participates_in CCO:I0019340 ! q9umf9-eif3s4-1 physical interaction relationship: participates_in CCO:I0019341 ! q9umf9-eif3s2-1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0026371 ! EIF3G_HUMAN-Phosphothreonine41 relationship: transforms_into CCO:B0026372 ! EIF3G_HUMAN-Phosphoserine42 [Term] id: CCO:B0026270 name: EIF3D_HUMAN def: "Eukaryotic translation initiation factor 3 subunit D" [UniProtKB:O15371] synonym: "eIF-3-zeta" EXACT [UniProtKB:O15371] synonym: "eIF3 p66" EXACT [UniProtKB:O15371] synonym: "eIF3d" EXACT [UniProtKB:O15371] synonym: "Eukaryotic translation initiation factor 3 subunit 7" EXACT [UniProtKB:O15371] xref: EMBL:AAD03466.1 xref: EMBL:AAH00328.1 xref: EMBL:AAH00469.1 xref: EMBL:AAH14912.1 xref: EMBL:AAH80515.1 xref: EMBL:AAH93100.1 xref: EMBL:AAH93686.1 xref: EMBL:AAI01478.1 xref: EMBL:AAP36045.1 xref: EMBL:CAA18440.1 xref: EMBL:CAG30375.1 xref: UniProtKB:O15371 xref: UniProtKB:Q3MJD9 xref: UniProtKB:Q5M9Q6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006351 ! EIF3D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0018523 ! phlda1-eif3s7-2 physical interaction relationship: participates_in CCO:I0019279 ! phlda1-eif3s7-1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0026365 ! EIF3D_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0026366 ! EIF3D_HUMAN-Phosphotyrosine318 relationship: transforms_into CCO:B0026367 ! EIF3D_HUMAN-Phosphoserine528 relationship: transforms_into CCO:B0026368 ! EIF3D_HUMAN-Phosphoserine529 relationship: transforms_into CCO:B0048253 ! EIF3D_HUMAN-Phosphothreonine548 [Term] id: CCO:B0026271 name: EIF3C_HUMAN def: "Eukaryotic translation initiation factor 3 subunit C" [UniProtKB:Q99613] synonym: "eIF3 p110" EXACT [UniProtKB:Q99613] synonym: "eIF3c" EXACT [UniProtKB:Q99613] synonym: "Eukaryotic translation initiation factor 3 subunit 8" EXACT [UniProtKB:Q99613] xref: EMBL:AAC27426.1 xref: EMBL:AAC27674.1 xref: EMBL:AAD03462.1 xref: EMBL:AAH00533.1 xref: EMBL:AAH01571.1 xref: EMBL:AAH71705.1 xref: EMBL:AAP35999.1 xref: EMBL:BAA91352.1 xref: EMBL:BAF84844.1 xref: EMBL:EAW50492.1 xref: UniProtKB:A8K7Z0 xref: UniProtKB:O00215 xref: UniProtKB:Q99613 xref: UniProtKB:Q9BW98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006350 ! EIF3C_human relationship: encoded_by CCO:G0014347 ! EIF3CL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0020316 ! p34-eif3s8 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0026357 ! EIF3C_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0026358 ! EIF3C_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0026359 ! EIF3C_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0026360 ! EIF3C_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0026361 ! EIF3C_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0026362 ! EIF3C_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0026363 ! EIF3C_HUMAN-Phosphothreonine524 relationship: transforms_into CCO:B0026364 ! EIF3C_HUMAN-Phosphoserine909 relationship: transforms_into CCO:B0064959 ! EIF3C_HUMAN-Phosphothreonine6 relationship: transforms_into CCO:B0064960 ! EIF3C_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0064961 ! EIF3C_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0064962 ! EIF3C_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0064963 ! EIF3C_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0064964 ! EIF3C_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0064965 ! EIF3C_HUMAN-Phosphoserine18 [Term] id: CCO:B0026272 name: EIF3E_HUMAN def: "Eukaryotic translation initiation factor 3 subunit E" [UniProtKB:P60228] synonym: "eIF-3 p48" EXACT [UniProtKB:P60228] synonym: "eIF3e" EXACT [UniProtKB:P60228] synonym: "Eukaryotic translation initiation factor 3 subunit 6" EXACT [UniProtKB:P60228] synonym: "Viral integration site protein INT-6 homolog" EXACT [UniProtKB:P60228] xref: EMBL:AAB58251.1 xref: EMBL:AAB88873.1 xref: EMBL:AAC51760.1 xref: EMBL:AAC51917.1 xref: EMBL:AAC51919.1 xref: EMBL:AAH00734.1 xref: EMBL:AAH08419.1 xref: EMBL:AAH16706.1 xref: EMBL:AAH17887.1 xref: EMBL:AAH21679.1 xref: UniProtKB:O43902 xref: UniProtKB:P60228 xref: UniProtKB:Q64058 xref: UniProtKB:Q64059 xref: UniProtKB:Q64252 xref: UniProtKB:Q8WVK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006352 ! EIF3E_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0015265 ! dkfzp434h1428-eif3s6 physical interaction relationship: participates_in CCO:I0018462 ! bat2-eif3s6 physical interaction relationship: participates_in CCO:I0020286 ! ddx24-eif3s6 physical interaction relationship: participates_in CCO:I0020301 ! eif3s6-hap1 physical interaction relationship: participates_in CCO:I0020328 ! gpaa1-eif3s6 physical interaction relationship: participates_in CCO:I0020386 ! nsf-eif3s6 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0026369 ! EIF3E_HUMAN-Phosphothreonine439 relationship: transforms_into CCO:B0026370 ! EIF3E_HUMAN-Phosphotyrosine445 relationship: transforms_into CCO:B0041300 ! EIF3E_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064966 ! EIF3E_HUMAN-Phosphoserine399 [Term] id: CCO:B0026273 name: EIF3I_HUMAN def: "Eukaryotic translation initiation factor 3 subunit I" [UniProtKB:Q13347] synonym: "eIF-3-beta" EXACT [UniProtKB:Q13347] synonym: "eIF3 p36" EXACT [UniProtKB:Q13347] synonym: "eIF3i" EXACT [UniProtKB:Q13347] synonym: "Eukaryotic translation initiation factor 3 subunit 2" EXACT [UniProtKB:Q13347] synonym: "TGF-beta receptor-interacting protein 1" EXACT [UniProtKB:Q13347] synonym: "TRIP-1" EXACT [UniProtKB:Q13347] xref: EMBL:AAC50224.1 xref: EMBL:AAC97144.1 xref: EMBL:AAH00413.1 xref: EMBL:AAH03140.1 xref: UniProtKB:Q13347 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006355 ! EIF3I_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0019341 ! q9umf9-eif3s2-1 physical interaction relationship: participates_in CCO:I0019342 ! eif3s2-eif3s1-1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0026373 ! EIF3I_HUMAN-Phosphotyrosine308 [Term] id: CCO:B0026274 name: EIF3K_HUMAN def: "Eukaryotic translation initiation factor 3 subunit K" [UniProtKB:Q9UBQ5] synonym: "eIF-3 p25" EXACT [UniProtKB:Q9UBQ5] synonym: "eIF-3 p28" EXACT [UniProtKB:Q9UBQ5] synonym: "eIF3k" EXACT [UniProtKB:Q9UBQ5] synonym: "Eukaryotic translation initiation factor 3 subunit 12" EXACT [UniProtKB:Q9UBQ5] synonym: "Muscle-specific gene M9 protein" EXACT [UniProtKB:Q9UBQ5] synonym: "PLAC-24" EXACT [UniProtKB:Q9UBQ5] xref: EMBL:AAD27784.1 xref: EMBL:AAD40193.1 xref: EMBL:AAH01031.1 xref: EMBL:AAH07335.2 xref: EMBL:AAH07559.1 xref: EMBL:AAK01365.1 xref: EMBL:AAP22070.1 xref: EMBL:AAQ13503.1 xref: EMBL:BAA76626.1 xref: UniProtKB:Q96IQ0 xref: UniProtKB:Q9UBQ5 xref: UniProtKB:Q9Y6D1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006357 ! EIF3K_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0015150 ! eif3s12-eif3s6ip physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0026377 ! EIF3K_HUMAN-Phosphoserine217 [Term] id: CCO:B0026275 name: EIF3B_HUMAN def: "Eukaryotic translation initiation factor 3 subunit B" [UniProtKB:P55884] synonym: "eIF-3-eta" EXACT [UniProtKB:P55884] synonym: "eIF3 p110" EXACT [UniProtKB:P55884] synonym: "eIF3 p116" EXACT [UniProtKB:P55884] synonym: "eIF3b" EXACT [UniProtKB:P55884] synonym: "Eukaryotic translation initiation factor 3 subunit 9" EXACT [UniProtKB:P55884] synonym: "hPrt1" EXACT [UniProtKB:P55884] synonym: "Prt1 homolog" EXACT [UniProtKB:P55884] xref: EMBL:AAB42010.1 xref: EMBL:AAC99479.1 xref: EMBL:AAH01173.1 xref: EMBL:AAI10866.1 xref: UniProtKB:P55884 xref: UniProtKB:Q2NL77 xref: UniProtKB:Q9UMF9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006349 ! EIF3B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: transforms_into CCO:B0026349 ! EIF3B_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0026350 ! EIF3B_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0026351 ! EIF3B_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0026352 ! EIF3B_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0026353 ! EIF3B_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0026354 ! EIF3B_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0026355 ! EIF3B_HUMAN-Phosphothreonine451 relationship: transforms_into CCO:B0026356 ! EIF3B_HUMAN-Phosphotyrosine525 relationship: transforms_into CCO:B0064956 ! EIF3B_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0064957 ! EIF3B_HUMAN-Phosphoserine81 relationship: transforms_into CCO:B0064958 ! EIF3B_HUMAN-Phosphoserine239 [Term] id: CCO:B0026276 name: AKTIP_HUMAN def: "AKT-interacting protein" [UniProtKB:Q9H8T0] synonym: "Ft1" EXACT [UniProtKB:Q9H8T0] synonym: "Fused toes protein homolog" EXACT [UniProtKB:Q9H8T0] xref: EMBL:AAH01134.1 xref: EMBL:BAB14524.1 xref: EMBL:CAG33589.1 xref: UniProtKB:Q9H8T0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006345 ! AKTIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008012 ! fts-rpa1 physical interaction relationship: participates_in CCO:I0015376 ! ctbp2-fts physical interaction relationship: participates_in CCO:I0019722 ! fts-pola2 physical interaction [Term] id: CCO:B0026277 name: EIF3F_HUMAN def: "Eukaryotic translation initiation factor 3 subunit F" [UniProtKB:O00303] synonym: "eIF-3-epsilon" EXACT [UniProtKB:O00303] synonym: "eIF3 p47 subunit" EXACT [UniProtKB:O00303] synonym: "eIF3f" EXACT [UniProtKB:O00303] synonym: "Eukaryotic translation initiation factor 3 subunit 5" EXACT [UniProtKB:O00303] xref: EMBL:AAD03467.1 xref: EMBL:AAH00490.1 xref: EMBL:AAP35540.1 xref: EMBL:BAC04577.1 xref: EMBL:CAG33240.1 xref: UniProtKB:O00303 xref: UniProtKB:Q6IB45 xref: UniProtKB:Q8N978 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006353 ! EIF3F_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: participates_in CCO:I0008102 ! eif3s5-ptn physical interaction relationship: participates_in CCO:I0008226 ! eif3s5-dkc1 physical interaction relationship: participates_in CCO:I0015611 ! eif3s5-hs1bp1 physical interaction relationship: participates_in CCO:I0019589 ! eif3s5-eef1a1 physical interaction relationship: participates_in CCO:I0019984 ! eif3s5-ga17 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation [Term] id: CCO:B0026278 name: EIF3J_HUMAN def: "Eukaryotic translation initiation factor 3 subunit J" [UniProtKB:O75822] synonym: "eIF-3-alpha" EXACT [UniProtKB:O75822] synonym: "eIF3 p35" EXACT [UniProtKB:O75822] synonym: "eIF3j" EXACT [UniProtKB:O75822] synonym: "Eukaryotic translation initiation factor 3 subunit 1" EXACT [UniProtKB:O75822] xref: EMBL:AAC78729.1 xref: EMBL:AAF24039.1 xref: EMBL:AAH02719.1 xref: EMBL:BAB14555.1 xref: UniProtKB:O75822 xref: UniProtKB:Q9BUD2 xref: UniProtKB:Q9H8Q2 xref: UniProtKB:Q9UI65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006356 ! EIF3J_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008345 ! tpd52l1-eif3s1 physical interaction relationship: participates_in CCO:I0008435 ! tada3l-eif3s1 physical interaction relationship: participates_in CCO:I0019340 ! q9umf9-eif3s4-1 physical interaction relationship: participates_in CCO:I0019341 ! q9umf9-eif3s2-1 physical interaction relationship: participates_in CCO:I0019342 ! eif3s2-eif3s1-1 physical interaction relationship: participates_in CCO:I0020060 ! maged1-eif3s1 physical interaction relationship: participates_in CCO:I0020326 ! golph2-eif3s1 physical interaction relationship: participates_in CCO:I0020565 ! gnb5-eif3s1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0026374 ! EIF3J_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0026375 ! EIF3J_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0026376 ! EIF3J_HUMAN-Phosphothreonine109 relationship: transforms_into CCO:B0041301 ! EIF3J_HUMAN-N-acetylalanine2 [Term] id: CCO:B0026279 name: IF3EI_HUMAN def: "Eukaryotic translation initiation factor 3 subunit E-interacting protein" [UniProtKB:Q9Y262] synonym: "Eukaryotic translation initiation factor 3 subunit 6-interacting protein" EXACT [UniProtKB:Q9Y262] xref: EMBL:AAD27002.1 xref: EMBL:AAD39841.1 xref: EMBL:AAH01101.1 xref: EMBL:AAH07510.1 xref: EMBL:AAH29265.1 xref: EMBL:AAQ13507.1 xref: EMBL:BAD96216.1 xref: EMBL:BAD96249.1 xref: EMBL:CAG30322.1 xref: EMBL:CAI21418.1 xref: UniProtKB:Q53HQ1 xref: UniProtKB:Q53HT4 xref: UniProtKB:Q5QTR1 xref: UniProtKB:Q5TI15 xref: UniProtKB:Q6ICD2 xref: UniProtKB:Q9Y262 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006362 ! EIF3EIP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000174 ! fibrillar center relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0008470 ! dnm2-eif3s6ip physical interaction relationship: participates_in CCO:I0015150 ! eif3s12-eif3s6ip physical interaction relationship: participates_in CCO:I0017331 ! xrn2-eif3s6ip physical interaction [Term] id: CCO:B0026336 name: AAPK1_HUMAN-Phosphoserine487 def: "Protein AAPK1_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:Q13131] xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001058 ! cAMP-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0026337 name: ANDR_HUMAN-Phosphotyrosine223 def: "Protein ANDR_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026338 name: ANDR_HUMAN-Phosphotyrosine267 def: "Protein ANDR_HUMAN with the residue 267 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026339 name: ANDR_HUMAN-Phosphotyrosine307 def: "Protein ANDR_HUMAN with the residue 307 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026340 name: ANDR_HUMAN-Phosphotyrosine346 def: "Protein ANDR_HUMAN with the residue 346 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026341 name: ANDR_HUMAN-Phosphotyrosine357 def: "Protein ANDR_HUMAN with the residue 357 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026342 name: ANDR_HUMAN-Phosphotyrosine362 def: "Protein ANDR_HUMAN with the residue 362 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026343 name: ANDR_HUMAN-Phosphotyrosine363 def: "Protein ANDR_HUMAN with the residue 363 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026344 name: ANDR_HUMAN-Phosphotyrosine393 def: "Protein ANDR_HUMAN with the residue 393 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026345 name: ANDR_HUMAN-Phosphotyrosine534 def: "Protein ANDR_HUMAN with the residue 534 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026346 name: ANDR_HUMAN-Phosphotyrosine551 def: "Protein ANDR_HUMAN with the residue 551 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026347 name: ANDR_HUMAN-Phosphotyrosine915 def: "Protein ANDR_HUMAN with the residue 915 substituted with Phosphotyrosine" [UniProtKB:P10275] comment: by CSK; xref: UniProtKB:P10275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001235 ! androgen receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001635 ! androgen binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:B0026348 name: BAT2_HUMAN-Phosphoserine1014 def: "Protein BAT2_HUMAN with the residue 1014 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0026349 name: EIF3B_HUMAN-Phosphoserine83 def: "Protein EIF3B_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026350 name: EIF3B_HUMAN-Phosphoserine85 def: "Protein EIF3B_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026351 name: EIF3B_HUMAN-Phosphoserine125 def: "Protein EIF3B_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026352 name: EIF3B_HUMAN-Phosphoserine152 def: "Protein EIF3B_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026353 name: EIF3B_HUMAN-Phosphoserine154 def: "Protein EIF3B_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026354 name: EIF3B_HUMAN-Phosphoserine164 def: "Protein EIF3B_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026355 name: EIF3B_HUMAN-Phosphothreonine451 def: "Protein EIF3B_HUMAN with the residue 451 substituted with Phosphothreonine" [UniProtKB:P55884] comment: By similarity xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026356 name: EIF3B_HUMAN-Phosphotyrosine525 def: "Protein EIF3B_HUMAN with the residue 525 substituted with Phosphotyrosine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0026357 name: EIF3C_HUMAN-Phosphoserine39 def: "Protein EIF3C_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026358 name: EIF3C_HUMAN-Phosphoserine95 def: "Protein EIF3C_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026359 name: EIF3C_HUMAN-Phosphoserine166 def: "Protein EIF3C_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026360 name: EIF3C_HUMAN-Phosphoserine178 def: "Protein EIF3C_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026361 name: EIF3C_HUMAN-Phosphoserine181 def: "Protein EIF3C_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026362 name: EIF3C_HUMAN-Phosphoserine182 def: "Protein EIF3C_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026363 name: EIF3C_HUMAN-Phosphothreonine524 def: "Protein EIF3C_HUMAN with the residue 524 substituted with Phosphothreonine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026364 name: EIF3C_HUMAN-Phosphoserine909 def: "Protein EIF3C_HUMAN with the residue 909 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0026365 name: EIF3D_HUMAN-Phosphoserine67 def: "Protein EIF3D_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:O15371] xref: UniProtKB:O15371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026270 ! EIF3D_HUMAN [Term] id: CCO:B0026366 name: EIF3D_HUMAN-Phosphotyrosine318 def: "Protein EIF3D_HUMAN with the residue 318 substituted with Phosphotyrosine" [UniProtKB:O15371] xref: UniProtKB:O15371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0026270 ! EIF3D_HUMAN [Term] id: CCO:B0026367 name: EIF3D_HUMAN-Phosphoserine528 def: "Protein EIF3D_HUMAN with the residue 528 substituted with Phosphoserine" [UniProtKB:O15371] xref: UniProtKB:O15371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026270 ! EIF3D_HUMAN [Term] id: CCO:B0026368 name: EIF3D_HUMAN-Phosphoserine529 def: "Protein EIF3D_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:O15371] xref: UniProtKB:O15371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026270 ! EIF3D_HUMAN [Term] id: CCO:B0026369 name: EIF3E_HUMAN-Phosphothreonine439 def: "Protein EIF3E_HUMAN with the residue 439 substituted with Phosphothreonine" [UniProtKB:P60228] comment: By similarity xref: UniProtKB:P60228 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:B0026370 name: EIF3E_HUMAN-Phosphotyrosine445 def: "Protein EIF3E_HUMAN with the residue 445 substituted with Phosphotyrosine" [UniProtKB:P60228] xref: UniProtKB:P60228 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:B0026371 name: EIF3G_HUMAN-Phosphothreonine41 def: "Protein EIF3G_HUMAN with the residue 41 substituted with Phosphothreonine" [UniProtKB:O75821] xref: UniProtKB:O75821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026269 ! EIF3G_HUMAN [Term] id: CCO:B0026372 name: EIF3G_HUMAN-Phosphoserine42 def: "Protein EIF3G_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:O75821] xref: UniProtKB:O75821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0026269 ! EIF3G_HUMAN [Term] id: CCO:B0026373 name: EIF3I_HUMAN-Phosphotyrosine308 def: "Protein EIF3I_HUMAN with the residue 308 substituted with Phosphotyrosine" [UniProtKB:Q13347] xref: UniProtKB:Q13347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0026273 ! EIF3I_HUMAN [Term] id: CCO:B0026374 name: EIF3J_HUMAN-Phosphoserine11 def: "Protein EIF3J_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:O75822] xref: UniProtKB:O75822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:B0026375 name: EIF3J_HUMAN-Phosphoserine13 def: "Protein EIF3J_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:O75822] xref: UniProtKB:O75822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:B0026376 name: EIF3J_HUMAN-Phosphothreonine109 def: "Protein EIF3J_HUMAN with the residue 109 substituted with Phosphothreonine" [UniProtKB:O75822] xref: UniProtKB:O75822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:B0026377 name: EIF3K_HUMAN-Phosphoserine217 def: "Protein EIF3K_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:Q9UBQ5] xref: UniProtKB:Q9UBQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005784 ! ribosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0026274 ! EIF3K_HUMAN [Term] id: CCO:B0026378 name: GRLF1_HUMAN-Phosphoserine1150 def: "Protein GRLF1_HUMAN with the residue 1150 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0026379 name: H2AX_HUMAN-Phosphothreonine121 def: "Protein H2AX_HUMAN with the residue 121 substituted with Phosphothreonine" [UniProtKB:P16104] xref: UniProtKB:P16104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:B0026380 name: JUB_HUMAN-Phosphoserine119 def: "Protein JUB_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q96IF1] xref: UniProtKB:Q96IF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0026254 ! JUB_HUMAN [Term] id: CCO:B0026381 name: JUB_HUMAN-Phosphoserine263 def: "Protein JUB_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q96IF1] xref: UniProtKB:Q96IF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026254 ! JUB_HUMAN [Term] id: CCO:B0026382 name: NF1_HUMAN-Phosphoserine2829 def: "Protein NF1_HUMAN with the residue 2829 substituted with Phosphoserine" [UniProtKB:P21359] xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001005 ! dendrite relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0026383 name: NUCL_HUMAN-Phosphothreonine99 def: "Protein NUCL_HUMAN with the residue 99 substituted with Phosphothreonine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0026384 name: NUCL_HUMAN-Phosphothreonine105 def: "Protein NUCL_HUMAN with the residue 105 substituted with Phosphothreonine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0026385 name: PDS5B_HUMAN-Phosphoserine1166 def: "Protein PDS5B_HUMAN with the residue 1166 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0026386 name: PDS5B_HUMAN-Phosphoserine1257 def: "Protein PDS5B_HUMAN with the residue 1257 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0026387 name: PDS5B_HUMAN-Phosphoserine1259 def: "Protein PDS5B_HUMAN with the residue 1259 substituted with Phosphoserine" [UniProtKB:Q9NTI5] comment: By similarity xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0026388 name: PDS5B_HUMAN-Phosphoserine1358 def: "Protein PDS5B_HUMAN with the residue 1358 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0026389 name: PDS5B_HUMAN-Phosphothreonine1367 def: "Protein PDS5B_HUMAN with the residue 1367 substituted with Phosphothreonine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0026390 name: PDS5B_HUMAN-Phosphothreonine1370 def: "Protein PDS5B_HUMAN with the residue 1370 substituted with Phosphothreonine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0026391 name: PDS5B_HUMAN-Phosphoserine1383 def: "Protein PDS5B_HUMAN with the residue 1383 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0026392 name: TCF19_HUMAN-Phosphoserine78 def: "Protein TCF19_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:Q9Y242] xref: UniProtKB:Q9Y242 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0026258 ! TCF19_HUMAN [Term] id: CCO:B0026393 name: ZMY11_HUMAN-Phosphoserine381 def: "Protein ZMY11_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q15326] xref: UniProtKB:Q15326 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026249 ! ZMY11_HUMAN [Term] id: CCO:B0026418 name: NUDT4_HUMAN def: "Diphosphoinositol polyphosphate phosphohydrolase 2" [UniProtKB:Q9NZJ9] synonym: "Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2" EXACT [UniProtKB:Q9NZJ9] synonym: "DIPP-2" EXACT [UniProtKB:Q9NZJ9] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9NZJ9] synonym: "EC 3.6.1.52" EXACT [UniProtKB:Q9NZJ9] synonym: "Nucleoside diphosphate-linked moiety X motif 4" EXACT [UniProtKB:Q9NZJ9] synonym: "Nudix motif 4" EXACT [UniProtKB:Q9NZJ9] xref: EMBL:AAF68855.1 xref: EMBL:AAF68856.1 xref: EMBL:AAF68857.1 xref: EMBL:AAF68858.2 xref: EMBL:AAF68859.1 xref: EMBL:AAF75563.1 xref: EMBL:AAH12069.1 xref: EMBL:AAH51310.1 xref: EMBL:AAV38912.1 xref: EMBL:AAV38913.1 xref: EMBL:BAD97217.1 xref: EMBL:BAE16985.1 xref: EMBL:CAH18283.1 xref: UniProtKB:Q4AEJ6 xref: UniProtKB:Q53EZ2 xref: UniProtKB:Q68DD7 xref: UniProtKB:Q9NPC5 xref: UniProtKB:Q9NS30 xref: UniProtKB:Q9NZJ9 xref: UniProtKB:Q9NZK0 xref: UniProtKB:Q9NZK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007905 ! NUDT4_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001946 ! diphosphoinositol-polyphosphate diphosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0001151 ! cyclic-nucleotide-mediated signaling [Term] id: CCO:B0026419 name: NUDT3_HUMAN def: "Diphosphoinositol polyphosphate phosphohydrolase 1" [UniProtKB:O95989] synonym: "Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1" EXACT [UniProtKB:O95989] synonym: "DIPP-1" EXACT [UniProtKB:O95989] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O95989] synonym: "EC 3.6.1.52" EXACT [UniProtKB:O95989] synonym: "Nucleoside diphosphate-linked moiety X motif 3" EXACT [UniProtKB:O95989] synonym: "Nudix motif 3" EXACT [UniProtKB:O95989] xref: EMBL:AAC83224.1 xref: EMBL:AAC83225.1 xref: EMBL:AAH07727.1 xref: EMBL:AAV38787.1 xref: EMBL:AAV38788.1 xref: EMBL:CAH72222.1 xref: EMBL:CAI19715.1 xref: UniProtKB:O95989 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007904 ! NUDT3_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001946 ! diphosphoinositol-polyphosphate diphosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015776 ! nudt3-sox30 physical interaction relationship: participates_in CCO:I0020387 ! nudt3-asb13 physical interaction relationship: participates_in CCO:I0020388 ! nudt3-rab17 physical interaction [Term] id: CCO:B0026435 name: UK114_HUMAN def: "Ribonuclease UK114" [UniProtKB:P52758] synonym: "14.5 kDa translational inhibitor protein" EXACT [UniProtKB:P52758] synonym: "EC 3.1.-.-" EXACT [UniProtKB:P52758] synonym: "p14.5" EXACT [UniProtKB:P52758] synonym: "UK114 antigen homolog" EXACT [UniProtKB:P52758] xref: EMBL:AAH10280.1 xref: EMBL:AAH12592.1 xref: EMBL:AAK01939.1 xref: EMBL:CAA64670.1 xref: EMBL:CAG46453.1 xref: UniProtKB:P52758 xref: UniProtKB:Q6FHU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008341 ! HRSP12_human relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000664 ! regulation of translational termination relationship: transforms_into CCO:B0035826 ! UK114_HUMAN-Phosphotyrosine21 [Term] id: CCO:B0026448 name: AT2C1_HUMAN def: "Calcium-transporting ATPase type 2C member 1" [UniProtKB:P98194] synonym: "ATP-dependent Ca(2+) pump PMR1" EXACT [UniProtKB:P98194] synonym: "ATPase 2C1" EXACT [UniProtKB:P98194] synonym: "EC 3.6.3.8" EXACT [UniProtKB:P98194] xref: EMBL:AAF26295.1 xref: EMBL:AAF26296.1 xref: EMBL:AAF27813.2 xref: EMBL:AAF35375.1 xref: EMBL:AAH28139.1 xref: EMBL:AAP30008.1 xref: EMBL:AAP30009.1 xref: EMBL:BAA91835.1 xref: EMBL:BAA92585.1 xref: EMBL:BAC11142.1 xref: EMBL:CAA09425.1 xref: UniProtKB:O76005 xref: UniProtKB:P98194 xref: UniProtKB:Q86V72 xref: UniProtKB:Q86V73 xref: UniProtKB:Q8N6V1 xref: UniProtKB:Q8NCJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007272 ! ATP2C1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001602 ! calcium-transporting ATPase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0026467 name: HSF1_HUMAN def: "Heat shock factor protein 1" [UniProtKB:Q00613] synonym: "Heat shock transcription factor 1" EXACT [UniProtKB:Q00613] synonym: "HSF 1" EXACT [UniProtKB:Q00613] synonym: "HSTF 1" EXACT [UniProtKB:Q00613] xref: EMBL:AAA52695.1 xref: EMBL:AAH14638.1 xref: EMBL:AAP36015.1 xref: UniProtKB:Q00613 xref: UniProtKB:Q53XT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007632 ! HSF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016195 ! hsf1-mk2-2 phosphorylation relationship: participates_in CCO:I0017779 ! hsf1-mk2-1 phosphorylation relationship: participates_in CCO:I0017942 ! mk2-hsf1 physical interaction relationship: participates_in CCO:I0018563 ! hsf1-mk2 physical interaction relationship: participates_in CCO:I0019312 ! hsf1-mk2-3 physical interaction relationship: participates_in CCO:I0020302 ! eno2-hsf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0034859 ! HSF1_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0034860 ! HSF1_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0034861 ! HSF1_HUMAN-Phosphothreonine323 relationship: transforms_into CCO:B0034862 ! HSF1_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0052424 ! HSF1_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0052425 ! HSF1_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0066923 ! HSF1_HUMAN-Phosphothreonine369 [Term] id: CCO:B0026475 name: Q6ZTI4_HUMAN xref: UniProtKB:Q6ZTI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0026476 name: A8MW26_HUMAN def: "Uncharacterized protein ENSP00000383589" [UniProtKB:A8MW26] xref: UniProtKB:A8MW26 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0026489 name: HSF2_HUMAN def: "Heat shock factor protein 2" [UniProtKB:Q03933] synonym: "Heat shock transcription factor 2" EXACT [UniProtKB:Q03933] synonym: "HSF 2" EXACT [UniProtKB:Q03933] synonym: "HSTF 2" EXACT [UniProtKB:Q03933] xref: EMBL:AAA36017.1 xref: EMBL:AAI12324.1 xref: EMBL:AAI21052.1 xref: EMBL:ABF47087.1 xref: EMBL:CAC14262.2 xref: EMBL:CAI20560.1 xref: UniProtKB:Q03933 xref: UniProtKB:Q2M1K4 xref: UniProtKB:Q9H445 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007633 ! HSF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0026498 name: TISB_HUMAN def: "Butyrate response factor 1" [UniProtKB:Q07352] synonym: "EGF-response factor 1" EXACT [UniProtKB:Q07352] synonym: "ERF-1" EXACT [UniProtKB:Q07352] synonym: "Protein TIS11B" EXACT [UniProtKB:Q07352] xref: EMBL:AAH18340.1 xref: EMBL:AAV38275.1 xref: EMBL:CAA55670.1 xref: EMBL:CAA67781.1 xref: UniProtKB:Q07352 xref: UniProtKB:Q13851 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008296 ! ZFP36L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015169 ! mapk14-zfp36l1 physical interaction relationship: participates_in CCO:I0019427 ! mapk14-zfp36l1-1 physical interaction relationship: participates_in CCO:I0020394 ! pafah1b2-zfp36l1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0002223 ! regulation of mRNA stability relationship: transforms_into CCO:B0035785 ! TISB_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0035786 ! TISB_HUMAN-Phosphoserine92 [Term] id: CCO:B0026499 name: TTP_HUMAN def: "Tristetraproline" [UniProtKB:P26651] synonym: "G0/G1 switch regulatory protein 24" EXACT [UniProtKB:P26651] synonym: "Growth factor-inducible nuclear protein NUP475" EXACT [UniProtKB:P26651] synonym: "Protein TIS11A" EXACT [UniProtKB:P26651] synonym: "TIS11" EXACT [UniProtKB:P26651] synonym: "TTP" EXACT [UniProtKB:P26651] synonym: "Zfp-36" EXACT [UniProtKB:P26651] synonym: "Zinc finger protein 36 homolog" EXACT [UniProtKB:P26651] xref: EMBL:AAA58489.1 xref: EMBL:AAA61240.1 xref: EMBL:AAC37600.1 xref: EMBL:AAH09693.1 xref: EMBL:AAV28731.1 xref: UniProtKB:P26651 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008326 ! ZFP36_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015888 ! exosc8-zfp36 physical interaction relationship: participates_in CCO:I0018109 ! zfp36-dcp1a physical interaction relationship: participates_in CCO:I0018110 ! zfp36-yjdc physical interaction relationship: participates_in CCO:I0018111 ! zfp36-rcd8-1 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002452 ! negative regulation of myeloid cell differentiation relationship: participates_in CCO:P0002954 ! RNA destabilization relationship: transforms_into CCO:B0039694 ! TTP_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0039695 ! TTP_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0039696 ! TTP_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0039697 ! TTP_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0039698 ! TTP_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0039699 ! TTP_HUMAN-Phosphothreonine257 relationship: transforms_into CCO:B0039700 ! TTP_HUMAN-Phosphoserine323 [Term] id: CCO:B0026502 name: A8MVD0_HUMAN xref: UniProtKB:A8MVD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0026523 name: GDE_HUMAN def: "Glycogen debranching enzyme" [UniProtKB:P35573] synonym: "Glycogen debrancher" EXACT [UniProtKB:P35573] xref: EMBL:AAB41040.1 xref: EMBL:AAB48466.1 xref: EMBL:AAB48467.1 xref: EMBL:AAB48468.1 xref: EMBL:AAB48469.1 xref: EMBL:AAB48470.1 xref: EMBL:AAH78663.1 xref: EMBL:BAA88405.1 xref: UniProtKB:P35573 xref: UniProtKB:P78354 xref: UniProtKB:P78544 xref: UniProtKB:Q6AZ90 xref: UniProtKB:Q9UF08 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0017902 ! AGL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008962 ! smad3-sry-3 physical interaction relationship: transforms_into CCO:B0066433 ! GDE_HUMAN-Phosphotyrosine584 [Term] id: CCO:B0026530 name: NPAS2_HUMAN def: "Neuronal PAS domain-containing protein 2" [UniProtKB:Q99743] synonym: "Basic-helix-loop-helix-PAS protein MOP4" EXACT [UniProtKB:Q99743] synonym: "Member of PAS protein 4" EXACT [UniProtKB:Q99743] synonym: "Neuronal PAS2" EXACT [UniProtKB:Q99743] xref: EMBL:AAB47250.1 xref: EMBL:AAC51211.1 xref: EMBL:AAH51351.2 xref: EMBL:AAH72383.1 xref: UniProtKB:Q86V96 xref: UniProtKB:Q99629 xref: UniProtKB:Q99743 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007893 ! NPAS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0008202 ! Hsp90 protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0026531 name: CLOCK_HUMAN def: "Circadian locomoter output cycles protein kaput" [UniProtKB:O15516] synonym: "EC 2.3.1.48" EXACT [UniProtKB:O15516] synonym: "hCLOCK" EXACT [UniProtKB:O15516] xref: EMBL:AAB83969.1 xref: EMBL:AAF13733.1 xref: EMBL:AAI26158.1 xref: EMBL:AAI26160.1 xref: EMBL:BAA20792.2 xref: EMBL:BAA21774.1 xref: UniProtKB:A0AV01 xref: UniProtKB:O14516 xref: UniProtKB:O15516 xref: UniProtKB:Q9UIT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007398 ! CLOCK_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0034669 ! CLOCK_HUMAN-Phosphoserine408 [Term] id: CCO:B0026532 name: Q53EU0_HUMAN def: "Clock variant" [UniProtKB:Q53EU0] xref: EMBL:BAD97269.1 xref: UniProtKB:Q53EU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0026533 name: PASD1_HUMAN def: "PAS domain-containing protein 1" [UniProtKB:Q8IV76] synonym: "Cancer/testis antigen 63" EXACT [UniProtKB:Q8IV76] synonym: "CT63" EXACT [UniProtKB:Q8IV76] synonym: "OX-TES-1" EXACT [UniProtKB:Q8IV76] xref: EMBL:AAH40301.1 xref: EMBL:AAQ01136.1 xref: EMBL:AAT49049.1 xref: EMBL:BAC05097.1 xref: UniProtKB:Q3MNE0 xref: UniProtKB:Q69HD7 xref: UniProtKB:Q8IV76 xref: UniProtKB:Q8N7X9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007951 ! PASD1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026534 name: A6NP27_HUMAN xref: UniProtKB:A6NP27 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0026578 name: A8MU92_HUMAN def: "Putative uncharacterized protein CASP8" [UniProtKB:A8MU92] xref: UniProtKB:A8MU92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017239 ! CASP8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0026583 name: SNX6_HUMAN def: "Sorting nexin-6" [UniProtKB:Q9UNH7] synonym: "TRAF4-associated factor 2" EXACT [UniProtKB:Q9UNH7] xref: EMBL:AAD24202.1 xref: EMBL:AAD27829.1 xref: UniProtKB:Q9UNH7 xref: UniProtKB:Q9Y449 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008195 ! SNX6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017450 ! disc1-snx6-1 physical interaction relationship: participates_in CCO:I0017451 ! mitap1-snx6 physical interaction relationship: participates_in CCO:I0017820 ! disc1-snx6 physical interaction relationship: participates_in CCO:I0019138 ! coil-snx6 physical interaction relationship: participates_in CCO:P0000717 ! negative regulation of epidermal growth factor receptor activity relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001273 ! negative regulation of transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0026585 name: SNX5_HUMAN def: "Sorting nexin-5" [UniProtKB:Q9Y5X3] xref: EMBL:AAD27828.1 xref: EMBL:AAH93623.1 xref: EMBL:AAH93980.1 xref: EMBL:BAA91914.1 xref: EMBL:CAC00471.1 xref: UniProtKB:Q52LC4 xref: UniProtKB:Q9BWP0 xref: UniProtKB:Q9Y5X3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008194 ! SNX5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020048 ! itsn1-snx5 physical interaction [Term] id: CCO:B0026600 name: P55G_HUMAN def: "Phosphatidylinositol 3-kinase regulatory subunit gamma" [UniProtKB:Q92569] synonym: "p55PIK" EXACT [UniProtKB:Q92569] synonym: "PI3-kinase p85 subunit gamma" EXACT [UniProtKB:Q92569] synonym: "PtdIns-3-kinase p85-gamma" EXACT [UniProtKB:Q92569] xref: EMBL:AAC39696.1 xref: EMBL:BAA13636.1 xref: EMBL:CAI21702.1 xref: UniProtKB:O60482 xref: UniProtKB:Q5T4P2 xref: UniProtKB:Q92569 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019278 ! PIK3R3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017643 ! p55g-cd19-1 physical interaction relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0069024 ! P55G_HUMAN-Phosphotyrosine199 relationship: transforms_into CCO:B0069025 ! P55G_HUMAN-Phosphotyrosine341 [Term] id: CCO:B0026602 name: P85B_HUMAN def: "Phosphatidylinositol 3-kinase regulatory subunit beta" [UniProtKB:O00459] synonym: "PI3-kinase p85 subunit beta" EXACT [UniProtKB:O00459] synonym: "PtdIns-3-kinase p85-beta" EXACT [UniProtKB:O00459] xref: EMBL:AAD22671.1 xref: EMBL:AAH70082.1 xref: EMBL:AAH90249.1 xref: EMBL:CAA56868.1 xref: UniProtKB:O00459 xref: UniProtKB:Q5EAT5 xref: UniProtKB:Q9UPH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019281 ! PIK3R2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0018433 ! hck-pik3r2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001152 ! negative regulation of anti-apoptosis relationship: transforms_into CCO:B0069038 ! P85B_HUMAN-Phosphotyrosine365 relationship: transforms_into CCO:B0069039 ! P85B_HUMAN-Phosphotyrosine464 relationship: transforms_into CCO:B0069040 ! P85B_HUMAN-Phosphotyrosine467 [Term] id: CCO:B0026605 name: Q8N381_HUMAN def: "Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma)" [UniProtKB:Q8N381] xref: EMBL:AAH21622.1 xref: UniProtKB:Q8N381 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0019278 ! PIK3R3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015463 ! drap1-pik3r3 physical interaction [Term] id: CCO:B0026606 name: Q05BV6_HUMAN def: "PIK3R2 protein" [UniProtKB:Q05BV6] xref: EMBL:AAH32647.1 xref: UniProtKB:Q05BV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019281 ! PIK3R2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005556 ! phosphoinositide 3-kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0026608 name: P85A_HUMAN def: "Phosphatidylinositol 3-kinase regulatory subunit alpha" [UniProtKB:P27986] synonym: "PI3-kinase p85 subunit alpha" EXACT [UniProtKB:P27986] synonym: "PI3K" EXACT [UniProtKB:P27986] synonym: "PtdIns-3-kinase p85-alpha" EXACT [UniProtKB:P27986] xref: EMBL:AAB04140.1 xref: EMBL:AAH30815.1 xref: EMBL:AAH94795.1 xref: EMBL:AAO15359.1 xref: EMBL:BAD97333.1 xref: UniProtKB:P27986 xref: UniProtKB:Q15747 xref: UniProtKB:Q4VBZ7 xref: UniProtKB:Q53EM6 xref: UniProtKB:Q8IXA2 xref: UniProtKB:Q8N1C5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019280 ! PIK3R1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006444 ! erbb2-egfr physical interaction relationship: participates_in CCO:I0006445 ! erbb2-egfr-1 physical interaction relationship: participates_in CCO:I0007304 ! erbb2-egfr-2 physical interaction relationship: participates_in CCO:I0007305 ! erbb2-egfr-3 physical interaction relationship: participates_in CCO:I0007453 ! gab2-grb2-1 physical interaction relationship: participates_in CCO:I0016317 ! p85a-erbb3-1 physical interaction relationship: participates_in CCO:I0017641 ! cd22-lyn-1 physical interaction relationship: participates_in CCO:I0017693 ! gab1-pik3r1-2 physical interaction relationship: participates_in CCO:I0017706 ! gab1-pik3r1-1 physical interaction relationship: participates_in CCO:I0018435 ! hck-pik3r1-1 physical interaction relationship: participates_in CCO:I0018530 ! p85a-erbb3-3 physical interaction relationship: participates_in CCO:I0018868 ! p85a-erbb3-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0002755 ! insulin-like growth factor receptor signaling pathway relationship: transforms_into CCO:B0069033 ! P85A_HUMAN-Phosphotyrosine452 relationship: transforms_into CCO:B0069034 ! P85A_HUMAN-Phosphotyrosine467 relationship: transforms_into CCO:B0069035 ! P85A_HUMAN-Phosphotyrosine556 relationship: transforms_into CCO:B0069036 ! P85A_HUMAN-Phosphotyrosine580 relationship: transforms_into CCO:B0069037 ! P85A_HUMAN-Phosphotyrosine607 [Term] id: CCO:B0026617 name: A8K6J2_HUMAN xref: UniProtKB:A8K6J2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0026618 name: Q5JYS9_HUMAN def: "Phospholipase C, beta 4" [UniProtKB:Q5JYS9] xref: EMBL:CAI42214.1 xref: EMBL:CAI43088.1 xref: UniProtKB:Q5JYS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019429 ! PLCB4_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0026622 name: A8MTK9_HUMAN def: "Uncharacterized protein ENSP00000383572" [UniProtKB:A8MTK9] xref: UniProtKB:A8MTK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0026626 name: PECA1_HUMAN def: "Platelet endothelial cell adhesion molecule precursor" [UniProtKB:P16284] synonym: "CD31 antigen" EXACT [UniProtKB:P16284] synonym: "EndoCAM" EXACT [UniProtKB:P16284] synonym: "GPIIA'" EXACT [UniProtKB:P16284] synonym: "PECAM-1" EXACT [UniProtKB:P16284] xref: EMBL:AAA36186.1 xref: EMBL:AAA36429.1 xref: EMBL:AAA60057.1 xref: EMBL:AAB28645.1 xref: EMBL:AAF91446.1 xref: EMBL:AAF91447.1 xref: EMBL:AAF91448.1 xref: EMBL:AAF91449.1 xref: EMBL:AAF91450.1 xref: EMBL:AAF91451.1 xref: EMBL:AAF91452.1 xref: EMBL:AAF91453.1 xref: EMBL:AAF91454.1 xref: EMBL:AAF91455.1 xref: EMBL:AAF91456.1 xref: EMBL:AAF91457.1 xref: EMBL:AAF91458.1 xref: EMBL:AAF91459.1 xref: EMBL:AAF91460.1 xref: EMBL:AAH22512.1 xref: EMBL:AAH51822.1 xref: EMBL:AAK84009.1 xref: EMBL:AAK84010.1 xref: EMBL:AAK84011.1 xref: UniProtKB:P16284 xref: UniProtKB:Q6LDA9 xref: UniProtKB:Q8TBH1 xref: UniProtKB:Q96RF5 xref: UniProtKB:Q96RF6 xref: UniProtKB:Q9NP65 xref: UniProtKB:Q9NPB7 xref: UniProtKB:Q9NPG9 xref: UniProtKB:Q9NQS9 xref: UniProtKB:Q9NQT0 xref: UniProtKB:Q9NQT1 xref: UniProtKB:Q9NQT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007963 ! PECAM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020102 ! pecam1-g22p1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035358 ! PECA1_HUMAN-Phosphotyrosine713 relationship: transforms_into CCO:B0069205 ! PECA1_HUMAN-Phosphotyrosine290 [Term] id: CCO:B0026635 name: K0174_HUMAN def: "Uncharacterized protein KIAA0174" [UniProtKB:P53990] synonym: "Putative MAPK-activating protein PM28" EXACT [UniProtKB:P53990] xref: EMBL:AAH00116.1 xref: EMBL:AAH00430.1 xref: EMBL:AAH04359.1 xref: EMBL:AAI03746.1 xref: EMBL:BAA11491.2 xref: EMBL:BAC77405.1 xref: EMBL:BAF85711.1 xref: UniProtKB:P53990 xref: UniProtKB:Q3SYM4 xref: UniProtKB:Q9BQ81 xref: UniProtKB:Q9BWN2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007691 ! KIAA0174_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016166 ! atxn1-kiaa0174 physical interaction relationship: participates_in CCO:I0017562 ! kiaa0174-atxn1 physical interaction relationship: transforms_into CCO:B0034942 ! K0174_HUMAN-Phosphotyrosine43 [Term] id: CCO:B0026670 name: TICN1_HUMAN def: "Testican-1 precursor" [UniProtKB:Q08629] synonym: "Protein SPOCK" EXACT [UniProtKB:Q08629] xref: EMBL:AAC24945.1 xref: EMBL:AAF43687.1 xref: EMBL:CAA51999.1 xref: UniProtKB:Q08629 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008291 ! SPOCK1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0026671 name: TICN2_HUMAN def: "Testican-2 precursor" [UniProtKB:Q92563] synonym: "SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2" EXACT [UniProtKB:Q92563] xref: EMBL:AAH23558.1 xref: EMBL:AAQ89280.1 xref: EMBL:BAA13404.2 xref: EMBL:CAA04774.1 xref: UniProtKB:Q6UW87 xref: UniProtKB:Q92563 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008292 ! SPOCK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017292 ! kiaa1206-spock2 physical interaction relationship: participates_in CCO:P0002409 ! regulation of cell differentiation relationship: transforms_into CCO:B0035783 ! TICN2_HUMAN-Phosphothreonine86 [Term] id: CCO:B0026696 name: MTMR9_HUMAN def: "Myotubularin-related protein 9" [UniProtKB:Q96QG7] xref: EMBL:AAH22003.1 xref: EMBL:AAH34990.1 xref: EMBL:AAH93788.1 xref: EMBL:AAI01624.1 xref: EMBL:BAA91170.1 xref: EMBL:CAC51114.1 xref: EMBL:CAC51115.1 xref: UniProtKB:Q52LU3 xref: UniProtKB:Q8WW11 xref: UniProtKB:Q96QG6 xref: UniProtKB:Q96QG7 xref: UniProtKB:Q9NX50 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022411 ! MTMR9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015378 ! mtmr9-spg21 physical interaction relationship: participates_in CCO:I0015725 ! ewsr1-mtmr9 physical interaction relationship: transforms_into CCO:B0068320 ! MTMR9_HUMAN-Phosphoserine548 [Term] id: CCO:B0026710 name: RGS4_HUMAN def: "Regulator of G-protein signaling 4" [UniProtKB:P49798] synonym: "RGP4" EXACT [UniProtKB:P49798] synonym: "RGS4" EXACT [UniProtKB:P49798] xref: EMBL:AAC50395.1 xref: EMBL:AAH00737.1 xref: EMBL:AAH51869.1 xref: EMBL:AAM12642.1 xref: EMBL:AAP35671.1 xref: EMBL:CAH73767.1 xref: UniProtKB:P49798 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008098 ! RGS4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0026717 name: RGS17_HUMAN def: "Regulator of G-protein signaling 17" [UniProtKB:Q9UGC6] synonym: "RGS17" EXACT [UniProtKB:Q9UGC6] xref: EMBL:AAF08978.3 xref: EMBL:AAH13117.1 xref: EMBL:AAM12652.1 xref: EMBL:AAP35643.1 xref: EMBL:CAI18900.1 xref: UniProtKB:Q5TF49 xref: UniProtKB:Q8TD61 xref: UniProtKB:Q9UGC6 xref: UniProtKB:Q9UJS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008091 ! RGS17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0035556 ! RGS17_HUMAN-Phosphotyrosine137 [Term] id: CCO:B0026726 name: MRGRF_HUMAN def: "Mas-related G-protein coupled receptor member F" [UniProtKB:Q96AM1] synonym: "G-protein coupled receptor 140" EXACT [UniProtKB:Q96AM1] synonym: "G-protein coupled receptor 168" EXACT [UniProtKB:Q96AM1] synonym: "Mas-related gene F protein" EXACT [UniProtKB:Q96AM1] xref: EMBL:AAH16964.1 xref: EMBL:BAC11628.1 xref: UniProtKB:Q8NBK8 xref: UniProtKB:Q96AM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007836 ! MRGPRF_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0026744 name: B2L13_HUMAN def: "Bcl-2-like 13 protein" [UniProtKB:Q9BXK5] synonym: "Bcl-rambo" EXACT [UniProtKB:Q9BXK5] synonym: "Protein Mil1" EXACT [UniProtKB:Q9BXK5] xref: EMBL:AAF03602.1 xref: EMBL:AAG09680.1 xref: EMBL:AAH07658.1 xref: EMBL:AAH16037.1 xref: EMBL:AAK15150.1 xref: EMBL:AAK27358.1 xref: EMBL:CAB61361.1 xref: EMBL:CAG30407.1 xref: UniProtKB:Q96B37 xref: UniProtKB:Q96IB7 xref: UniProtKB:Q9BXK5 xref: UniProtKB:Q9BY01 xref: UniProtKB:Q9HC05 xref: UniProtKB:Q9UFE0 xref: UniProtKB:Q9UKN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007298 ! BCL2L13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015338 ! bcl2l13-gabarapl2 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0034583 ! B2L13_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0034584 ! B2L13_HUMAN-Phosphoserine426 [Term] id: CCO:B0026768 name: MK10_HUMAN def: "Mitogen-activated protein kinase 10" [UniProtKB:P53779] synonym: "c-Jun N-terminal kinase 3" EXACT [UniProtKB:P53779] synonym: "EC 2.7.11.24" EXACT [UniProtKB:P53779] synonym: "MAP kinase p49 3F12" EXACT [UniProtKB:P53779] synonym: "Stress-activated protein kinase JNK3" EXACT [UniProtKB:P53779] xref: EMBL:AAC50101.1 xref: EMBL:AAC50604.1 xref: EMBL:AAC50605.1 xref: EMBL:AAH35057.1 xref: EMBL:EAX05963.1 xref: UniProtKB:A6NFS3 xref: UniProtKB:P53779 xref: UniProtKB:Q15707 xref: UniProtKB:Q49AP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007824 ! MAPK10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019763 ! mapk10-gtf3c1 physical interaction relationship: participates_in CCO:I0019764 ! mapk10-unc119 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0035195 ! MK10_HUMAN-Phosphothreonine221 relationship: transforms_into CCO:B0035196 ! MK10_HUMAN-Phosphotyrosine223 [Term] id: CCO:B0026769 name: MK09_HUMAN def: "Mitogen-activated protein kinase 9" [UniProtKB:P45984] synonym: "c-Jun N-terminal kinase 2" EXACT [UniProtKB:P45984] synonym: "EC 2.7.11.24" EXACT [UniProtKB:P45984] synonym: "JNK-55" EXACT [UniProtKB:P45984] synonym: "Stress-activated protein kinase JNK2" EXACT [UniProtKB:P45984] xref: EMBL:AAA56831.1 xref: EMBL:AAA74740.1 xref: EMBL:AAC50606.1 xref: EMBL:AAC50608.1 xref: EMBL:AAC50609.1 xref: EMBL:AAH32539.1 xref: EMBL:AAY46156.1 xref: EMBL:CAG38817.1 xref: UniProtKB:P45984 xref: UniProtKB:Q15708 xref: UniProtKB:Q15710 xref: UniProtKB:Q15711 xref: UniProtKB:Q8N5C5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007823 ! MAPK9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001071 ! JUN kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019765 ! mapk9-kiaa1377 physical interaction relationship: participates_in CCO:I0020067 ! mapk9-acp5 physical interaction relationship: participates_in CCO:I0020363 ! mapk9-xpnpep1 physical interaction relationship: participates_in CCO:I0020364 ! mapk9-xpo7 physical interaction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0035193 ! MK09_HUMAN-Phosphothreonine183 relationship: transforms_into CCO:B0035194 ! MK09_HUMAN-Phosphotyrosine185 [Term] id: CCO:B0026813 name: CD014_HUMAN def: "Uncharacterized protein C4orf14" [UniProtKB:Q8NC60] xref: EMBL:AAH04894.1 xref: EMBL:BAC05262.1 xref: EMBL:BAC11311.1 xref: UniProtKB:Q8N7L6 xref: UniProtKB:Q8NC60 xref: UniProtKB:Q9BSQ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022104 ! C4orf14_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: participates_in CCO:I0020228 ! arf1-c4orf14 physical interaction relationship: participates_in CCO:I0020370 ! mpp3-c4orf14 physical interaction relationship: participates_in CCO:I0020620 ! pdcd8-c4orf14 physical interaction [Term] id: CCO:B0026837 name: A8MRA5_HUMAN def: "Putative uncharacterized protein WDHD1" [UniProtKB:A8MRA5] xref: UniProtKB:A8MRA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008352 ! WDHD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0026846 name: CNTFR_HUMAN def: "Ciliary neurotrophic factor receptor alpha precursor" [UniProtKB:P26992] synonym: "CNTFR alpha" EXACT [UniProtKB:P26992] xref: EMBL:AAA35707.1 xref: EMBL:AAA91337.1 xref: EMBL:AAH01492.1 xref: UniProtKB:P26992 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007405 ! CNTFR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001245 ! ciliary neurotrophic factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004221 ! cytokine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0015075 ! appbp2-cntfr physical interaction relationship: participates_in CCO:I0015775 ! cntfr-plscr1 physical interaction relationship: participates_in CCO:I0015814 ! cntfr-krtap4_12 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0026851 name: HERP1_HUMAN def: "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein" [UniProtKB:Q15011] synonym: "Methyl methanesulfonate (MMF)-inducible fragment protein 1" EXACT [UniProtKB:Q15011] xref: EMBL:AAC09355.1 xref: EMBL:AAC09357.1 xref: EMBL:AAH00086.1 xref: EMBL:AAH08320.1 xref: EMBL:AAH09739.1 xref: EMBL:AAH32673.1 xref: EMBL:BAA03521.1 xref: EMBL:BAB07891.1 xref: EMBL:BAB19010.1 xref: UniProtKB:O60644 xref: UniProtKB:Q15011 xref: UniProtKB:Q96D92 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022306 ! HERPUD1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015312 ! ewsr1-herpud1 physical interaction relationship: participates_in CCO:I0020331 ! herpud1-rpa2 physical interaction relationship: participates_in CCO:I0020570 ! herpud1-impa2 physical interaction [Term] id: CCO:B0026855 name: ARI4B_HUMAN def: "AT-rich interactive domain-containing protein 4B" [UniProtKB:Q4LE39] synonym: "180 kDa Sin3-associated polypeptide" EXACT [UniProtKB:Q4LE39] synonym: "ARID domain-containing protein 4B" EXACT [UniProtKB:Q4LE39] synonym: "Breast cancer-associated antigen BRCAA1" EXACT [UniProtKB:Q4LE39] synonym: "Histone deacetylase complex subunit SAP180" EXACT [UniProtKB:Q4LE39] synonym: "Retinoblastoma-binding protein 1-like 1" EXACT [UniProtKB:Q4LE39] synonym: "Sin3-associated polypeptide p180" EXACT [UniProtKB:Q4LE39] xref: EMBL:AAD41239.1 xref: EMBL:AAF23433.3 xref: EMBL:AAF28341.2 xref: EMBL:AAF36964.1 xref: EMBL:AAH48959.1 xref: EMBL:AAH62536.1 xref: EMBL:AAI04633.1 xref: EMBL:AAI30419.1 xref: EMBL:AAO63590.1 xref: EMBL:BAA89794.1 xref: EMBL:BAB14428.1 xref: EMBL:BAE06114.1 xref: EMBL:CAB63731.1 xref: EMBL:CAI13747.2 xref: EMBL:CAI13749.1 xref: EMBL:CAI13751.1 xref: EMBL:CAI22961.2 xref: EMBL:CAI22962.1 xref: EMBL:CAI46047.1 xref: UniProtKB:A1L465 xref: UniProtKB:Q3MHV4 xref: UniProtKB:Q4LE39 xref: UniProtKB:Q5HY99 xref: UniProtKB:Q5T2C2 xref: UniProtKB:Q5T2C3 xref: UniProtKB:Q5T2C4 xref: UniProtKB:Q5T2C5 xref: UniProtKB:Q5T2C6 xref: UniProtKB:Q6P600 xref: UniProtKB:Q86UX1 xref: UniProtKB:Q86WR4 xref: UniProtKB:Q9H915 xref: UniProtKB:Q9NYU3 xref: UniProtKB:Q9NZB6 xref: UniProtKB:Q9NZG4 xref: UniProtKB:Q9P2W4 xref: UniProtKB:Q9UF62 xref: UniProtKB:Q9Y6E1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007264 ! ARID4B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0034561 ! ARI4B_HUMAN-Phosphoserine710 relationship: transforms_into CCO:B0034562 ! ARI4B_HUMAN-Phosphoserine712 relationship: transforms_into CCO:B0034563 ! ARI4B_HUMAN-Phosphoserine713 relationship: transforms_into CCO:B0034564 ! ARI4B_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0034565 ! ARI4B_HUMAN-Phosphothreonine1022 relationship: transforms_into CCO:B0034566 ! ARI4B_HUMAN-Phosphoserine1029 relationship: transforms_into CCO:B0063578 ! ARI4B_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0063579 ! ARI4B_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0063580 ! ARI4B_HUMAN-Phosphoserine778 relationship: transforms_into CCO:B0063581 ! ARI4B_HUMAN-Phosphoserine790 relationship: transforms_into CCO:B0063582 ! ARI4B_HUMAN-Phosphothreonine793 relationship: transforms_into CCO:B0063583 ! ARI4B_HUMAN-Phosphoserine912 relationship: transforms_into CCO:B0063584 ! ARI4B_HUMAN-Phosphothreonine1150 relationship: transforms_into CCO:B0063585 ! ARI4B_HUMAN-Phosphoserine1152 relationship: transforms_into CCO:B0063586 ! ARI4B_HUMAN-Phosphoserine1153 relationship: transforms_into CCO:B0063587 ! ARI4B_HUMAN-Phosphoserine1155 relationship: transforms_into CCO:B0063588 ! ARI4B_HUMAN-Phosphoserine1159 [Term] id: CCO:B0026862 name: A8K7L7_HUMAN def: "cDNA FLJ76919, highly similar to Homo sapiens retinoic acid receptor, beta (RARB), transcript variant 1, mRNA" [UniProtKB:A8K7L7] xref: EMBL:BAF84721.1 xref: UniProtKB:A8K7L7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0026863 name: A8MUP8_HUMAN def: "Putative uncharacterized protein RARA (Retinoic acid receptor, alpha, isoform CRA_e)" [UniProtKB:A8MUP8] xref: EMBL:EAW60657.1 xref: UniProtKB:A8MUP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005427 ! RARA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0026865 name: SORC1_HUMAN def: "VPS10 domain-containing receptor SorCS1 precursor" [UniProtKB:Q8WY21] synonym: "hSorCS" EXACT [UniProtKB:Q8WY21] xref: EMBL:AAL56667.1 xref: EMBL:AAM43811.1 xref: EMBL:AAM43812.1 xref: EMBL:BAD92379.1 xref: EMBL:CAH70582.1 xref: EMBL:CAH73442.1 xref: EMBL:CAI14367.1 xref: EMBL:CAI16407.1 xref: EMBL:CAI40753.1 xref: EMBL:CAI40754.1 xref: EMBL:CAI40755.1 xref: UniProtKB:Q59GG7 xref: UniProtKB:Q5JVT7 xref: UniProtKB:Q5JVT8 xref: UniProtKB:Q5VY14 xref: UniProtKB:Q86WQ1 xref: UniProtKB:Q86WQ2 xref: UniProtKB:Q8WY21 xref: UniProtKB:Q9H1Y1 xref: UniProtKB:Q9H1Y2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019983 ! SORCS1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0026866 name: SORC3_HUMAN def: "VPS10 domain-containing receptor SorCS3 precursor" [UniProtKB:Q9UPU3] xref: EMBL:BAA83011.2 xref: EMBL:CAH70023.1 xref: EMBL:CAH70335.1 xref: EMBL:CAH70477.1 xref: EMBL:CAH70813.1 xref: EMBL:CAH72221.1 xref: EMBL:CAI64579.1 xref: UniProtKB:Q5VXF9 xref: UniProtKB:Q9NQJ2 xref: UniProtKB:Q9UPU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019985 ! SORCS3_human relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0026867 name: SORC2_HUMAN def: "VPS10 domain-containing receptor SorCS2 precursor" [UniProtKB:Q96PQ0] xref: EMBL:AAL04014.1 xref: EMBL:BAA92567.1 xref: UniProtKB:Q96PQ0 xref: UniProtKB:Q9P2L7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019984 ! SORCS2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0026912 name: PEX6_HUMAN def: "Peroxisome assembly factor 2" [UniProtKB:Q13608] synonym: "PAF-2" EXACT [UniProtKB:Q13608] synonym: "Peroxin-6" EXACT [UniProtKB:Q13608] synonym: "Peroxisomal biogenesis factor 6" EXACT [UniProtKB:Q13608] synonym: "Peroxisomal-type ATPase 1" EXACT [UniProtKB:Q13608] xref: EMBL:AAC50655.1 xref: EMBL:AAF62564.1 xref: EMBL:AAH48331.1 xref: EMBL:BAA12069.1 xref: EMBL:BAB83046.1 xref: UniProtKB:Q13608 xref: UniProtKB:Q8WYQ2 xref: UniProtKB:Q99476 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007966 ! PEX6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_function CCO:F0005696 ! ATPase activity, coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0019304 ! pex26-pex6 physical interaction relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0026978 name: DPH3_HUMAN def: "DPH3 homolog" [UniProtKB:Q96FX2] synonym: "CSL-type zinc finger-containing protein 2" EXACT [UniProtKB:Q96FX2] synonym: "DelGEF-interacting protein 1" EXACT [UniProtKB:Q96FX2] synonym: "DelGIP1" EXACT [UniProtKB:Q96FX2] xref: EMBL:AAH10181.1 xref: UniProtKB:Q96FX2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007471 ! DPH3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017352 ! zcsl2-gnefr-1 physical interaction relationship: participates_in CCO:I0017353 ! zcsl2-gnefr-3 physical interaction relationship: participates_in CCO:I0018299 ! zcsl2-gnefr-2 physical interaction [Term] id: CCO:B0027056 name: A8MWU7_HUMAN def: "Putative uncharacterized protein GABRG2" [UniProtKB:A8MWU7] xref: UniProtKB:A8MWU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011428 ! GABRG2_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0027058 name: A8MX51_HUMAN xref: UniProtKB:A8MX51 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway [Term] id: CCO:B0027079 name: GT2D1_HUMAN def: "General transcription factor II-I repeat domain-containing protein 1" [UniProtKB:Q9UHL9] synonym: "General transcription factor III" EXACT [UniProtKB:Q9UHL9] synonym: "GTF2I repeat domain-containing protein 1" EXACT [UniProtKB:Q9UHL9] synonym: "Muscle TFII-I repeat domain-containing protein 1" EXACT [UniProtKB:Q9UHL9] synonym: "MusTRD1/BEN" EXACT [UniProtKB:Q9UHL9] synonym: "Slow-muscle-fiber enhancer-binding protein" EXACT [UniProtKB:Q9UHL9] synonym: "USE B1-binding protein" EXACT [UniProtKB:Q9UHL9] synonym: "Williams-Beuren syndrome chromosomal region 11 protein" EXACT [UniProtKB:Q9UHL9] xref: EMBL:AAD14687.2 xref: EMBL:AAD27668.1 xref: EMBL:AAF17358.1 xref: EMBL:AAF19786.1 xref: EMBL:AAF21796.1 xref: EMBL:AAH18136.1 xref: EMBL:AAP21877.1 xref: EMBL:AAS00362.1 xref: UniProtKB:O95444 xref: UniProtKB:Q75MX7 xref: UniProtKB:Q86UM3 xref: UniProtKB:Q8WVC4 xref: UniProtKB:Q9UHK8 xref: UniProtKB:Q9UHL9 xref: UniProtKB:Q9UI91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018087 ! GTF2IRD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066640 ! GT2D1_HUMAN-Phosphoserine448 relationship: transforms_into CCO:B0066641 ! GT2D1_HUMAN-Phosphoserine654 [Term] id: CCO:B0027081 name: GTF2I_HUMAN def: "General transcription factor II-I" [UniProtKB:P78347] synonym: "BAP-135" EXACT [UniProtKB:P78347] synonym: "Bruton tyrosine kinase-associated protein 135" EXACT [UniProtKB:P78347] synonym: "BTK-associated protein 135" EXACT [UniProtKB:P78347] synonym: "GTFII-I" EXACT [UniProtKB:P78347] synonym: "SPIN" EXACT [UniProtKB:P78347] synonym: "SRF-Phox1-interacting protein" EXACT [UniProtKB:P78347] synonym: "TFII-I" EXACT [UniProtKB:P78347] synonym: "Williams-Beuren syndrome chromosomal region 6 protein" EXACT [UniProtKB:P78347] xref: EMBL:AAB48826.1 xref: EMBL:AAB70791.1 xref: EMBL:AAC08312.1 xref: EMBL:AAC08313.1 xref: EMBL:AAC08314.1 xref: EMBL:AAC08315.1 xref: EMBL:AAH04472.1 xref: EMBL:AAH70484.1 xref: EMBL:AAL93085.1 xref: EMBL:CAA75163.1 xref: UniProtKB:O14743 xref: UniProtKB:O15359 xref: UniProtKB:O43546 xref: UniProtKB:O43588 xref: UniProtKB:O43589 xref: UniProtKB:P78347 xref: UniProtKB:Q9BSZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018090 ! GTF2I_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015945 ! btk-gtf21-2 physical interaction relationship: participates_in CCO:I0015946 ! btk-gtf21-3 physical interaction relationship: participates_in CCO:I0017192 ! nfkb2-gtf2i physical interaction relationship: participates_in CCO:I0017327 ! lsm8-gtf2i physical interaction relationship: participates_in CCO:I0018064 ! btk-gtf21-6 physical interaction relationship: participates_in CCO:I0018196 ! btk-gtf21-5 phosphorylation relationship: participates_in CCO:I0019257 ! btk-gtf21-4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066642 ! GTF2I_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0066643 ! GTF2I_HUMAN-Phosphoserine103 relationship: transforms_into CCO:B0066644 ! GTF2I_HUMAN-Phosphoserine207 relationship: transforms_into CCO:B0066645 ! GTF2I_HUMAN-Phosphoserine210 relationship: transforms_into CCO:B0066646 ! GTF2I_HUMAN-Phosphotyrosine248 relationship: transforms_into CCO:B0066647 ! GTF2I_HUMAN-Phosphotyrosine318 relationship: transforms_into CCO:B0066648 ! GTF2I_HUMAN-Phosphotyrosine398 relationship: transforms_into CCO:B0066649 ! GTF2I_HUMAN-Phosphotyrosine503 relationship: transforms_into CCO:B0066650 ! GTF2I_HUMAN-Phosphoserine515 relationship: transforms_into CCO:B0066651 ! GTF2I_HUMAN-Phosphoserine517 relationship: transforms_into CCO:B0066652 ! GTF2I_HUMAN-Phosphothreonine558 relationship: transforms_into CCO:B0066653 ! GTF2I_HUMAN-Phosphoserine668 relationship: transforms_into CCO:B0066654 ! GTF2I_HUMAN-Phosphoserine674 relationship: transforms_into CCO:B0066655 ! GTF2I_HUMAN-Phosphoserine679 relationship: transforms_into CCO:B0066656 ! GTF2I_HUMAN-Phosphothreonine687 relationship: transforms_into CCO:B0066657 ! GTF2I_HUMAN-Phosphoserine823 [Term] id: CCO:B0027148 name: S61A2_HUMAN def: "Protein transport protein Sec61 subunit alpha isoform 2" [UniProtKB:Q9H9S3] synonym: "Sec61 alpha-2" EXACT [UniProtKB:Q9H9S3] xref: EMBL:AAK29084.1 xref: EMBL:BAB14148.1 xref: UniProtKB:Q9H9S3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008162 ! SEC61A2_human relationship: has_function CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction [Term] id: CCO:B0027154 name: S61A1_HUMAN def: "Protein transport protein Sec61 subunit alpha isoform 1" [UniProtKB:P61619] synonym: "Sec61 alpha-1" EXACT [UniProtKB:P61619] xref: EMBL:AAD27765.1 xref: EMBL:AAD39847.1 xref: EMBL:AAK29083.1 xref: EMBL:BAC11283.1 xref: EMBL:BAC11298.1 xref: EMBL:BAC11434.1 xref: EMBL:CAD38592.1 xref: EMBL:CAI46127.1 xref: UniProtKB:P38378 xref: UniProtKB:P57726 xref: UniProtKB:P61619 xref: UniProtKB:Q5JPF8 xref: UniProtKB:Q8N0Z4 xref: UniProtKB:Q8N3U3 xref: UniProtKB:Q8NC71 xref: UniProtKB:Q9BU16 xref: UniProtKB:Q9Y2R3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008161 ! SEC61A1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0017029 ! tnfrsf1a-sec61a1 physical interaction [Term] id: CCO:B0027165 name: CDKL2_HUMAN def: "Cyclin-dependent kinase-like 2" [UniProtKB:Q92772] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q92772] synonym: "Protein kinase p56 KKIAMRE" EXACT [UniProtKB:Q92772] synonym: "Serine/threonine-protein kinase KKIAMRE" EXACT [UniProtKB:Q92772] xref: EMBL:AAC50918.1 xref: EMBL:AAH93646.1 xref: EMBL:AAH93981.1 xref: UniProtKB:Q92772 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017320 ! CDKL2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0027184 name: Q6ZQQ5_HUMAN xref: UniProtKB:Q6ZQQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase [Term] id: CCO:B0027190 name: ABLM1_HUMAN def: "Actin-binding LIM protein 1" [UniProtKB:O14639] synonym: "abLIM-1" EXACT [UniProtKB:O14639] synonym: "Actin-binding double zinc finger protein" EXACT [UniProtKB:O14639] synonym: "Actin-binding LIM protein family member 1" EXACT [UniProtKB:O14639] synonym: "LIMAB1" EXACT [UniProtKB:O14639] synonym: "Limatin" EXACT [UniProtKB:O14639] xref: EMBL:AAC51676.1 xref: EMBL:AAH02448.1 xref: EMBL:BAA06681.2 xref: EMBL:CAH18679.1 xref: EMBL:CAI10908.1 xref: EMBL:CAI40136.1 xref: EMBL:CAI40140.1 xref: UniProtKB:O14639 xref: UniProtKB:Q15039 xref: UniProtKB:Q5JVV1 xref: UniProtKB:Q5T6N5 xref: UniProtKB:Q68CQ9 xref: UniProtKB:Q9BUP1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022021 ! ABLIM1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015197 ! ablim1-traf2 physical interaction relationship: participates_in CCO:I0015413 ! ablim1-ldoc1 physical interaction relationship: participates_in CCO:I0015496 ! ablim1-tsc22d4 physical interaction relationship: participates_in CCO:I0019421 ! ablim1-ldoc1-1 physical interaction relationship: transforms_into CCO:B0065282 ! ABLM1_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0065283 ! ABLM1_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0065284 ! ABLM1_HUMAN-Phosphotyrosine357 relationship: transforms_into CCO:B0065285 ! ABLM1_HUMAN-Phosphoserine367 relationship: transforms_into CCO:B0065286 ! ABLM1_HUMAN-Phosphotyrosine373 relationship: transforms_into CCO:B0065287 ! ABLM1_HUMAN-Phosphotyrosine396 relationship: transforms_into CCO:B0065288 ! ABLM1_HUMAN-Phosphotyrosine406 relationship: transforms_into CCO:B0065289 ! ABLM1_HUMAN-Phosphotyrosine410 relationship: transforms_into CCO:B0065290 ! ABLM1_HUMAN-Phosphoserine431 relationship: transforms_into CCO:B0065291 ! ABLM1_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0065292 ! ABLM1_HUMAN-Phosphotyrosine439 relationship: transforms_into CCO:B0065293 ! ABLM1_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0065294 ! ABLM1_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0065295 ! ABLM1_HUMAN-Phosphoserine458 relationship: transforms_into CCO:B0065296 ! ABLM1_HUMAN-Phosphotyrosine461 relationship: transforms_into CCO:B0065297 ! ABLM1_HUMAN-Phosphoserine473 relationship: transforms_into CCO:B0065298 ! ABLM1_HUMAN-Phosphoserine587 relationship: transforms_into CCO:B0065299 ! ABLM1_HUMAN-Phosphoserine655 relationship: transforms_into CCO:B0065300 ! ABLM1_HUMAN-Phosphoserine706 [Term] id: CCO:B0027200 name: FPR1_HUMAN def: "fMet-Leu-Phe receptor" [UniProtKB:P21462] synonym: "fMLP receptor" EXACT [UniProtKB:P21462] synonym: "FPR" EXACT [UniProtKB:P21462] synonym: "N-formyl peptide receptor" EXACT [UniProtKB:P21462] synonym: "N-formylpeptide chemoattractant receptor" EXACT [UniProtKB:P21462] xref: EMBL:AAA16863.1 xref: EMBL:AAA35846.1 xref: EMBL:AAA35847.1 xref: EMBL:AAA36362.1 xref: EMBL:AAD14906.1 xref: EMBL:AAF87842.1 xref: EMBL:AAH05315.1 xref: EMBL:AAP36097.1 xref: EMBL:AAP58403.1 xref: UniProtKB:P21462 xref: UniProtKB:Q14939 xref: UniProtKB:Q7Z6A4 xref: UniProtKB:Q86U52 xref: UniProtKB:Q9NS48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007554 ! FPR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: transforms_into CCO:B0034806 ! FPR1_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0034807 ! FPR1_HUMAN-Phosphothreonine329 relationship: transforms_into CCO:B0034808 ! FPR1_HUMAN-Phosphothreonine331 relationship: transforms_into CCO:B0034809 ! FPR1_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0034810 ! FPR1_HUMAN-Phosphothreonine334 relationship: transforms_into CCO:B0034811 ! FPR1_HUMAN-Phosphothreonine336 relationship: transforms_into CCO:B0034812 ! FPR1_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0034813 ! FPR1_HUMAN-Phosphothreonine339 [Term] id: CCO:B0027270 name: FDFT_HUMAN def: "Squalene synthetase" [UniProtKB:P37268] synonym: "EC 2.5.1.21" EXACT [UniProtKB:P37268] synonym: "Farnesyl-diphosphate farnesyltransferase" EXACT [UniProtKB:P37268] synonym: "FPP:FPP farnesyltransferase" EXACT [UniProtKB:P37268] synonym: "SQS" EXACT [UniProtKB:P37268] synonym: "SS" EXACT [UniProtKB:P37268] xref: EMBL:AAA36645.1 xref: EMBL:AAA60582.1 xref: EMBL:AAB33404.1 xref: EMBL:AAH03573.1 xref: EMBL:AAH09251.1 xref: EMBL:AAH29641.1 xref: EMBL:CAA48896.1 xref: UniProtKB:P37268 xref: UniProtKB:Q96GT0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007529 ! FDFT1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000731 ! farnesyl-diphosphate farnesyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020225 ! anxa5-fdft1 physical interaction relationship: participates_in CCO:I0020445 ! ruvbl2-fdft1 physical interaction [Term] id: CCO:B0027449 name: TINAL_HUMAN def: "Tubulointerstitial nephritis antigen-like precursor" [UniProtKB:Q9GZM7] synonym: "Glucocorticoid-inducible protein 5" EXACT [UniProtKB:Q9GZM7] synonym: "OLRG-2" EXACT [UniProtKB:Q9GZM7] synonym: "Oxidized LDL-responsive gene 2 protein" EXACT [UniProtKB:Q9GZM7] synonym: "TIN Ag-related protein" EXACT [UniProtKB:Q9GZM7] synonym: "TIN-Ag-RP" EXACT [UniProtKB:Q9GZM7] synonym: "Tubulointerstitial nephritis antigen-related protein" EXACT [UniProtKB:Q9GZM7] xref: EMBL:AAG33699.1 xref: EMBL:AAG38876.1 xref: EMBL:AAG40154.1 xref: EMBL:AAH09048.1 xref: EMBL:AAH64633.1 xref: EMBL:AAL55753.1 xref: EMBL:AAQ88787.1 xref: EMBL:BAB18636.1 xref: EMBL:BAB18727.1 xref: EMBL:BAB55403.1 xref: EMBL:BAB84950.1 xref: EMBL:BAC11596.1 xref: UniProtKB:Q8TEJ9 xref: UniProtKB:Q8WZ23 xref: UniProtKB:Q96GZ4 xref: UniProtKB:Q96JW3 xref: UniProtKB:Q9GZM7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022716 ! TINAGL1_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0015454 ! mdfi-tinagl1 physical interaction relationship: participates_in CCO:I0020357 ! tinagl1-med31 physical interaction [Term] id: CCO:B0027467 name: MCA1_HUMAN def: "Multisynthetase complex auxiliary component p43" [UniProtKB:Q12904] xref: EMBL:AAA62202.1 xref: EMBL:AAH14051.1 xref: EMBL:CAG47076.1 xref: UniProtKB:Q12904 xref: UniProtKB:Q6FG28 xref: UniProtKB:Q96CQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007817 ! SCYE1_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005862 ! cell surface binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000838 ! aminoacyl-tRNA synthetase multienzyme complex relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0027476 name: A1E5M1_HUMAN def: "Phosphodiesterase PDE7B2" [UniProtKB:A1E5M1] xref: EMBL:ABL14249.1 xref: UniProtKB:A1E5M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007957 ! PDE7B_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0027477 name: PDE7B_HUMAN def: "cAMP-specific 3',5'-cyclic phosphodiesterase 7B" [UniProtKB:Q9NP56] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q9NP56] xref: EMBL:AAH75082.1 xref: EMBL:AAH75083.1 xref: EMBL:BAA96537.1 xref: EMBL:CAB92441.1 xref: UniProtKB:Q9NP56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007957 ! PDE7B_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000587 ! 3',5'-cyclic-AMP phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069185 ! PDE7B_HUMAN-Phosphoserine45 [Term] id: CCO:B0027478 name: PDE7A_HUMAN def: "High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A" [UniProtKB:Q13946] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q13946] synonym: "HCP1" EXACT [UniProtKB:Q13946] synonym: "TM22" EXACT [UniProtKB:Q13946] xref: EMBL:AAA35644.2 xref: EMBL:AAB65772.1 xref: UniProtKB:O15380 xref: UniProtKB:Q13946 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007956 ! PDE7A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035355 ! PDE7A_HUMAN-Phosphoserine84 [Term] id: CCO:B0027481 name: Q4VXJ0_HUMAN def: "Phosphodiesterase 7B" [UniProtKB:Q4VXJ0] xref: EMBL:CAI95286.1 xref: UniProtKB:Q4VXJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007957 ! PDE7B_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0027486 name: Q96T72_HUMAN def: "cAMP-specific cyclic nucleotide phosphodiesterase PDE7A3" [UniProtKB:Q96T72] xref: EMBL:AAK57640.1 xref: UniProtKB:Q96T72 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0027493 name: TYRO3_HUMAN def: "Tyrosine-protein kinase receptor TYRO3 precursor" [UniProtKB:Q06418] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q06418] synonym: "Tyrosine-protein kinase byk" EXACT [UniProtKB:Q06418] synonym: "Tyrosine-protein kinase DTK" EXACT [UniProtKB:Q06418] synonym: "Tyrosine-protein kinase RSE" EXACT [UniProtKB:Q06418] synonym: "Tyrosine-protein kinase SKY" EXACT [UniProtKB:Q06418] xref: EMBL:AAA19236.1 xref: EMBL:AAC50070.1 xref: EMBL:AAH49368.1 xref: EMBL:AAH51756.1 xref: EMBL:BAA04467.1 xref: EMBL:BAA21781.1 xref: EMBL:CAA51396.1 xref: UniProtKB:O14953 xref: UniProtKB:Q06418 xref: UniProtKB:Q86VR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020396 ! TYRO3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071645 ! TYRO3_HUMAN-Phosphotyrosine685 relationship: transforms_into CCO:B0071646 ! TYRO3_HUMAN-Phosphotyrosine686 [Term] id: CCO:B0027514 name: PEBP1_HUMAN def: "Phosphatidylethanolamine-binding protein 1" [UniProtKB:P30086] synonym: "HCNPpp" EXACT [UniProtKB:P30086] synonym: "Neuropolypeptide h3" EXACT [UniProtKB:P30086] synonym: "PEBP-1" EXACT [UniProtKB:P30086] synonym: "Prostatic-binding protein" EXACT [UniProtKB:P30086] synonym: "Raf kinase inhibitor protein" EXACT [UniProtKB:P30086] synonym: "RKIP" EXACT [UniProtKB:P30086] xref: EMBL:AAD14234.1 xref: EMBL:AAH08714.1 xref: EMBL:AAH17396.1 xref: EMBL:AAH31102.1 xref: EMBL:BAA03684.1 xref: EMBL:CAA53031.1 xref: EMBL:CAA59404.1 xref: UniProtKB:P30086 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022500 ! PEBP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0001896 ! phosphatidylethanolamine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020095 ! pbp-stc2 physical interaction relationship: participates_in CCO:I0020593 ! mgc5309-pbp physical interaction relationship: transforms_into CCO:B0069202 ! PEBP1_HUMAN-Phosphothreonine42 relationship: transforms_into CCO:B0069203 ! PEBP1_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0069204 ! PEBP1_HUMAN-Phosphoserine54 [Term] id: CCO:B0027516 name: PRP4B_HUMAN def: "Serine/threonine-protein kinase PRP4 homolog" [UniProtKB:Q13523] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13523] synonym: "PRP4 kinase" EXACT [UniProtKB:Q13523] synonym: "PRP4 pre-mRNA-processing factor 4 homolog" EXACT [UniProtKB:Q13523] xref: EMBL:AAB03268.1 xref: EMBL:AAH09844.1 xref: EMBL:AAH34969.1 xref: EMBL:AAK38155.1 xref: EMBL:AAM19101.1 xref: EMBL:BAA25462.1 xref: EMBL:BAF83933.1 xref: EMBL:CAI20480.1 xref: EMBL:CAI42121.1 xref: EMBL:EAW55146.1 xref: UniProtKB:A8K5C9 xref: UniProtKB:Q13523 xref: UniProtKB:Q5D0F6 xref: UniProtKB:Q5TAY8 xref: UniProtKB:Q8IVC3 xref: UniProtKB:Q8TDP2 xref: UniProtKB:Q96QT7 xref: UniProtKB:Q9UEE6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008013 ! PRPF4B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018846 ! polr3f-prpf4b-1 physical interaction relationship: participates_in CCO:I0020406 ! polr3f-prpf4b physical interaction relationship: transforms_into CCO:B0035440 ! PRP4B_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0035441 ! PRP4B_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0035442 ! PRP4B_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0035443 ! PRP4B_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0035444 ! PRP4B_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0035445 ! PRP4B_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0035446 ! PRP4B_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0035447 ! PRP4B_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0035448 ! PRP4B_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0035449 ! PRP4B_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0035450 ! PRP4B_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0035451 ! PRP4B_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0035452 ! PRP4B_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0035453 ! PRP4B_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0035454 ! PRP4B_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0035455 ! PRP4B_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0035456 ! PRP4B_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0035457 ! PRP4B_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0035458 ! PRP4B_HUMAN-Phosphothreonine385 relationship: transforms_into CCO:B0035459 ! PRP4B_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0035460 ! PRP4B_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0035461 ! PRP4B_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0035462 ! PRP4B_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0035463 ! PRP4B_HUMAN-Phosphoserine431 relationship: transforms_into CCO:B0035464 ! PRP4B_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0035465 ! PRP4B_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0035466 ! PRP4B_HUMAN-Phosphothreonine576 relationship: transforms_into CCO:B0035467 ! PRP4B_HUMAN-Phosphoserine578 relationship: transforms_into CCO:B0035468 ! PRP4B_HUMAN-Phosphoserine580 relationship: transforms_into CCO:B0035469 ! PRP4B_HUMAN-Phosphotyrosine849 relationship: transforms_into CCO:B0035470 ! PRP4B_HUMAN-Phosphoserine852 relationship: transforms_into CCO:B0069548 ! PRP4B_HUMAN-Phosphotyrosine140 relationship: transforms_into CCO:B0069549 ! PRP4B_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0069550 ! PRP4B_HUMAN-Phosphoserine144 relationship: transforms_into CCO:B0069551 ! PRP4B_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0069552 ! PRP4B_HUMAN-Phosphoserine519 relationship: transforms_into CCO:B0069553 ! PRP4B_HUMAN-Phosphoserine520 [Term] id: CCO:B0027548 name: Q5JWE9_HUMAN def: "GNAS complex locus" [UniProtKB:Q5JWE9] xref: EMBL:CAI42569.1 xref: EMBL:CAI42934.1 xref: EMBL:CAI43076.1 xref: UniProtKB:Q5JWE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027550 name: GNAS2_HUMAN def: "Guanine nucleotide-binding protein G(s) subunit alpha isoforms short" [UniProtKB:P63092] synonym: "Adenylate cyclase-stimulating G alpha protein" EXACT [UniProtKB:P63092] xref: EMBL:AAA52583.1 xref: EMBL:AAA53146.1 xref: EMBL:AAA53147.1 xref: EMBL:AAA53149.1 xref: EMBL:AAB60334.2 xref: EMBL:AAH02722.1 xref: EMBL:AAH08855.1 xref: EMBL:AAH22875.1 xref: EMBL:AAH66923.1 xref: EMBL:AAI04929.1 xref: EMBL:AAM12611.1 xref: EMBL:AAM12612.1 xref: EMBL:AAP88907.1 xref: EMBL:CAA27996.1 xref: EMBL:CAA27997.1 xref: EMBL:CAA30084.1 xref: EMBL:CAI42546.1 xref: EMBL:CAI42547.1 xref: EMBL:CAI42549.1 xref: EMBL:CAI42914.1 xref: EMBL:CAI42915.1 xref: EMBL:CAI42917.1 xref: UniProtKB:P04895 xref: UniProtKB:P63092 xref: UniProtKB:Q12927 xref: UniProtKB:Q5JWD2 xref: UniProtKB:Q5JWD4 xref: UniProtKB:Q5JWD5 xref: UniProtKB:Q6NR75 xref: UniProtKB:Q6NXS0 xref: UniProtKB:Q8TBC0 xref: UniProtKB:Q96H70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066490 ! GNAS2_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0066491 ! GNAS2_HUMAN-ADP-ribosylarginine201 [Term] id: CCO:B0027551 name: GNAL_HUMAN def: "Guanine nucleotide-binding protein G(olf) subunit alpha" [UniProtKB:P38405] synonym: "Adenylate cyclase-stimulating G alpha protein, olfactory type" EXACT [UniProtKB:P38405] xref: EMBL:AAC37535.1 xref: EMBL:AAD00085.1 xref: EMBL:AAM12607.1 xref: UniProtKB:P38405 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017943 ! GNAL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000730 ! dopamine receptor, adenylate cyclase activating pathway relationship: transforms_into CCO:B0066487 ! GNAL_HUMAN-ADP-ribosylarginine188 [Term] id: CCO:B0027553 name: Q5FWY2_HUMAN def: "GNAS complex locus" [UniProtKB:Q5FWY2] xref: EMBL:AAH89157.2 xref: UniProtKB:Q5FWY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027554 name: GNAS1_HUMAN def: "Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas" [UniProtKB:Q5JWF2] synonym: "Adenylate cyclase-stimulating G alpha protein" EXACT [UniProtKB:Q5JWF2] synonym: "Extra large alphas protein" EXACT [UniProtKB:Q5JWF2] synonym: "XLalphas" EXACT [UniProtKB:Q5JWF2] xref: EMBL:AAX51890.1 xref: EMBL:CAA12164.1 xref: EMBL:CAA12165.1 xref: EMBL:CAB83215.1 xref: EMBL:CAI42566.2 xref: EMBL:CAI42567.2 xref: EMBL:CAI42932.2 xref: EMBL:CAI42933.2 xref: EMBL:CAI43073.2 xref: EMBL:CAI43074.2 xref: EMBL:CAM28315.1 xref: UniProtKB:A2A2S3 xref: UniProtKB:O75684 xref: UniProtKB:O75685 xref: UniProtKB:Q5JW67 xref: UniProtKB:Q5JWF1 xref: UniProtKB:Q5JWF2 xref: UniProtKB:Q9NY42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066488 ! GNAS1_HUMAN-Phosphoserine694 relationship: transforms_into CCO:B0066489 ! GNAS1_HUMAN-ADP-ribosylarginine844 [Term] id: CCO:B0027555 name: O60726_HUMAN def: "Mutant guanine nucleotide-binding protein G(S), alpha subunit" [UniProtKB:O60726] xref: EMBL:AAC16860.1 xref: UniProtKB:O60726 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027556 name: A6NI00_HUMAN def: "Putative uncharacterized protein GNAS" [UniProtKB:A6NI00] xref: UniProtKB:A6NI00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027557 name: Q5JW64_HUMAN def: "GNAS complex locus" [UniProtKB:Q5JW64] xref: EMBL:CAI42571.1 xref: EMBL:CAI43078.1 xref: UniProtKB:Q5JW64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027558 name: Q14455_HUMAN def: "Alpha subunit of GsGTP binding protein" [UniProtKB:Q14455] xref: EMBL:CAA39484.1 xref: UniProtKB:Q14455 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021089 ! GSA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway [Term] id: CCO:B0027559 name: Q5JWD1_HUMAN def: "GNAS complex locus" [UniProtKB:Q5JWD1] xref: EMBL:CAI42550.1 xref: UniProtKB:Q5JWD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027560 name: O75632_HUMAN def: "Guanine nucleotide-binding protein Gs alpha subunit isoform L2" [UniProtKB:O75632] xref: EMBL:AAC34896.1 xref: UniProtKB:O75632 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027561 name: O75633_HUMAN def: "Guanine nucleotide-binding protein Gs alpha subunit isoform L3" [UniProtKB:O75633] xref: EMBL:AAC34897.1 xref: UniProtKB:O75633 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027562 name: Q86XU3_HUMAN def: "Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type" [UniProtKB:Q86XU3] synonym: "Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type, isoform CRA_a" EXACT [UniProtKB:Q86XU3] xref: EMBL:AAH50021.1 xref: EMBL:EAX01573.1 xref: UniProtKB:Q86XU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017943 ! GNAL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027564 name: Q5JWE8_HUMAN def: "GNAS complex locus" [UniProtKB:Q5JWE8] xref: EMBL:CAI42570.2 xref: EMBL:CAI42935.2 xref: EMBL:CAI43077.2 xref: UniProtKB:Q5JWE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027571 name: SLIT2_HUMAN def: "Slit homolog 2 protein precursor" [UniProtKB:O94813] synonym: "Slit-2" EXACT [UniProtKB:O94813] xref: EMBL:AAD04309.1 xref: EMBL:AAD25539.1 xref: EMBL:AAI17191.1 xref: EMBL:BAA35185.1 xref: UniProtKB:O94813 xref: UniProtKB:O95710 xref: UniProtKB:Q17RU3 xref: UniProtKB:Q9Y5Q7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019935 ! SLIT2_human relationship: has_function CCO:F0001304 ! follicle-stimulating hormone receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0002950 ! positive regulation of axonogenesis [Term] id: CCO:B0027573 name: Q5T0V3_HUMAN def: "Slit homolog 1 (Drosophila)" [UniProtKB:Q5T0V3] xref: EMBL:CAI14256.1 xref: UniProtKB:Q5T0V3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021144 ! SLIT1_human relationship: has_function CCO:F0001304 ! follicle-stimulating hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027574 name: Q5T0V2_HUMAN def: "Slit homolog 1 (Drosophila)" [UniProtKB:Q5T0V2] xref: EMBL:CAI14257.1 xref: UniProtKB:Q5T0V2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021144 ! SLIT1_human relationship: has_function CCO:F0001304 ! follicle-stimulating hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0027580 name: A0JNU9_HUMAN def: "TBC1D1 protein" [UniProtKB:A0JNU9] xref: EMBL:AAI26980.1 xref: UniProtKB:A0JNU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020180 ! TBC1D1_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0027581 name: TBCD1_HUMAN def: "TBC1 domain family member 1" [UniProtKB:Q86TI0] xref: EMBL:AAH50321.3 xref: EMBL:BAA83060.1 xref: EMBL:BAB55057.1 xref: UniProtKB:Q86TI0 xref: UniProtKB:Q96K82 xref: UniProtKB:Q9UPP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020180 ! TBC1D1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071225 ! TBCD1_HUMAN-Phosphotyrosine113 [Term] id: CCO:B0027593 name: CDIPT_HUMAN def: "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" [UniProtKB:O14735] synonym: "EC 2.7.8.11" EXACT [UniProtKB:O14735] synonym: "Phosphatidylinositol synthase" EXACT [UniProtKB:O14735] synonym: "PI synthase" EXACT [UniProtKB:O14735] synonym: "PtdIns synthase" EXACT [UniProtKB:O14735] xref: EMBL:AAB94860.1 xref: EMBL:AAH01444.1 xref: EMBL:AAP35965.1 xref: EMBL:BAD18505.1 xref: EMBL:CAG46813.1 xref: UniProtKB:O14735 xref: UniProtKB:Q6FGU1 xref: UniProtKB:Q6ZN70 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007364 ! CDIPT_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000400 ! CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity relationship: has_function CCO:F0001978 ! phosphatidylinositol transporter activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017010 ! tnfrsf1a-cdipt physical interaction [Term] id: CCO:B0027730 name: SIN1_HUMAN def: "Target of rapamycin complex 2 subunit MAPKAP1" [UniProtKB:Q9BPZ7] synonym: "Mitogen-activated protein kinase 2-associated protein 1" EXACT [UniProtKB:Q9BPZ7] synonym: "SAPK-interacting protein 1" EXACT [UniProtKB:Q9BPZ7] synonym: "Stress-activated map kinase-interacting protein 1" EXACT [UniProtKB:Q9BPZ7] synonym: "TORC2 subunit MAPKAP1" EXACT [UniProtKB:Q9BPZ7] xref: EMBL:AAA36551.1 xref: EMBL:AAH02326.1 xref: EMBL:AAH03044.1 xref: EMBL:AAS90839.1 xref: EMBL:AAS90840.1 xref: EMBL:AAS90841.1 xref: EMBL:AAS90842.1 xref: EMBL:AAT46478.1 xref: EMBL:AAT46479.1 xref: EMBL:AAT46480.1 xref: EMBL:BAF82749.1 xref: EMBL:CAH56311.1 xref: EMBL:CAI39500.1 xref: EMBL:CAI39506.1 xref: EMBL:CAI39507.1 xref: EMBL:CAI39888.1 xref: EMBL:CAI39891.1 xref: EMBL:CAI39892.1 xref: EMBL:EAW87630.1 xref: EMBL:EAW87631.1 xref: EMBL:EAW87632.1 xref: UniProtKB:A8K1Z5 xref: UniProtKB:B1AMA4 xref: UniProtKB:Q00426 xref: UniProtKB:Q5JSV5 xref: UniProtKB:Q5JSV6 xref: UniProtKB:Q5JSV9 xref: UniProtKB:Q658R0 xref: UniProtKB:Q699U1 xref: UniProtKB:Q699U2 xref: UniProtKB:Q699U3 xref: UniProtKB:Q699U4 xref: UniProtKB:Q6GVJ0 xref: UniProtKB:Q6GVJ1 xref: UniProtKB:Q6GVJ2 xref: UniProtKB:Q9BPZ7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022655 ! MAPKAP1_human relationship: has_function CCO:F0003512 ! Ras GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0015540 ! cdc42ep1-mapkap1 physical interaction relationship: transforms_into CCO:B0070534 ! SIN1_HUMAN-Phosphoserine510 [Term] id: CCO:B0027842 name: MYH1_HUMAN def: "Myosin-1" [UniProtKB:P12882] synonym: "MyHC-2x" EXACT [UniProtKB:P12882] synonym: "MyHC-IIx/d" EXACT [UniProtKB:P12882] synonym: "Myosin heavy chain 1" EXACT [UniProtKB:P12882] synonym: "Myosin heavy chain 2x" EXACT [UniProtKB:P12882] synonym: "Myosin heavy chain IIx/d" EXACT [UniProtKB:P12882] synonym: "Myosin heavy chain, skeletal muscle, adult 1" EXACT [UniProtKB:P12882] xref: EMBL:AAD29951.1 xref: EMBL:AAI14546.1 xref: EMBL:CAA27380.1 xref: UniProtKB:P12882 xref: UniProtKB:Q14CA4 xref: UniProtKB:Q9Y622 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007848 ! MYH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016152 ! baz1b-myo1c physical interaction relationship: participates_in CCO:I0016321 ! smarca5-myo1c physical interaction relationship: participates_in CCO:I0017735 ! baz1b-myo1c-1 physical interaction relationship: transforms_into CCO:B0035223 ! MYH1_HUMAN-N6,N6,N6-trimethyllysine130 relationship: transforms_into CCO:B0035224 ! MYH1_HUMAN-Phosphoserine1928 relationship: transforms_into CCO:B0035225 ! MYH1_HUMAN-Phosphothreonine1933 [Term] id: CCO:B0027846 name: A8K4V1_HUMAN def: "cDNA FLJ76812, highly similar to Homo sapiens IQ motif containing GTPase activating protein 2 (IQGAP2), mRNA" [UniProtKB:A8K4V1] xref: EMBL:BAF83755.1 xref: UniProtKB:A8K4V1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001727 ! ubiquinol-cytochrome-c reductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0027932 name: Q6J1T2_HUMAN def: "Intersectin 1 isoform 7" [UniProtKB:Q6J1T2] xref: EMBL:AAT36645.1 xref: UniProtKB:Q6J1T2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013101 ! ITSN1_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0027933 name: Q6J1T1_HUMAN def: "Intersectin 1 isoform 6" [UniProtKB:Q6J1T1] xref: EMBL:AAT36646.1 xref: UniProtKB:Q6J1T1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013101 ! ITSN1_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0027936 name: Q14BD4_HUMAN def: "ITSN1 protein" [UniProtKB:Q14BD4] xref: EMBL:AAI16186.1 xref: UniProtKB:Q14BD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013101 ! ITSN1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0027945 name: ITSN1_HUMAN def: "Intersectin-1" [UniProtKB:Q15811] synonym: "SH3 domain-containing protein 1A" EXACT [UniProtKB:Q15811] synonym: "SH3P17" EXACT [UniProtKB:Q15811] xref: EMBL:AAC50592.1 xref: EMBL:AAC78610.1 xref: EMBL:AAC78611.1 xref: EMBL:AAC80437.1 xref: EMBL:AAD29952.1 xref: EMBL:AAD29953.1 xref: EMBL:AAD53183.1 xref: UniProtKB:O95216 xref: UniProtKB:Q15811 xref: UniProtKB:Q9UET5 xref: UniProtKB:Q9UK60 xref: UniProtKB:Q9UNK1 xref: UniProtKB:Q9UNK2 xref: UniProtKB:Q9UQ92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013101 ! ITSN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017914 ! disc1-itsn1-2 physical interaction relationship: participates_in CCO:I0018087 ! disc1-itsn1 physical interaction relationship: participates_in CCO:I0018369 ! disc1-itsn1-1 physical interaction relationship: participates_in CCO:I0018825 ! cdc42-itsn1-2 physical interaction relationship: participates_in CCO:I0019253 ! cdc42-itsn1-1 direct interaction relationship: participates_in CCO:I0019751 ! itsn1-eef1a1 physical interaction relationship: participates_in CCO:I0019752 ! itsn1-kif5a physical interaction relationship: participates_in CCO:I0019753 ! itsn1-unc119 physical interaction relationship: participates_in CCO:I0020047 ! itsn1-mrpl20 physical interaction relationship: participates_in CCO:I0020048 ! itsn1-snx5 physical interaction relationship: participates_in CCO:I0020352 ! itsn1-smarcc2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0040623 ! ITSN1_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0040624 ! ITSN1_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0040625 ! ITSN1_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0040626 ! ITSN1_HUMAN-Phosphoserine559 relationship: transforms_into CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: transforms_into CCO:B0040628 ! ITSN1_HUMAN-Phosphoserine904 relationship: transforms_into CCO:B0040629 ! ITSN1_HUMAN-Phosphothreonine977 relationship: transforms_into CCO:B0040630 ! ITSN1_HUMAN-Phosphoserine1137 [Term] id: CCO:B0028029 name: GO45_HUMAN def: "Golgin-45" [UniProtKB:Q9H2G9] synonym: "Basic leucine zipper nuclear factor 1" EXACT [UniProtKB:Q9H2G9] synonym: "JEM-1" EXACT [UniProtKB:Q9H2G9] synonym: "p45 basic leucine-zipper nuclear factor" EXACT [UniProtKB:Q9H2G9] xref: EMBL:AAB63110.1 xref: EMBL:AAG37821.1 xref: EMBL:AAG37822.1 xref: EMBL:AAG37835.1 xref: EMBL:AAH20716.1 xref: EMBL:CAI19242.1 xref: UniProtKB:O15298 xref: UniProtKB:Q5T531 xref: UniProtKB:Q9GZX4 xref: UniProtKB:Q9H2G9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007598 ! BLZF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0066505 ! GO45_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0066506 ! GO45_HUMAN-Phosphothreonine369 [Term] id: CCO:B0028072 name: Q5JTM4_HUMAN def: "Regulatory factor X, 3 (Influences HLA class II expression)" [UniProtKB:Q5JTM4] xref: EMBL:CAI41217.1 xref: UniProtKB:Q5JTM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019685 ! RFX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028073 name: RFX3_HUMAN def: "Transcription factor RFX3" [UniProtKB:P48380] synonym: "Regulatory factor X 3" EXACT [UniProtKB:P48380] xref: EMBL:AAH22191.1 xref: EMBL:AAH67778.1 xref: EMBL:CAA53706.1 xref: EMBL:CAI13403.1 xref: EMBL:CAI13404.1 xref: EMBL:CAI40199.1 xref: EMBL:CAI40200.1 xref: EMBL:CAI41215.1 xref: EMBL:CAI41216.1 xref: UniProtKB:P48380 xref: UniProtKB:Q5JTL7 xref: UniProtKB:Q5JTL8 xref: UniProtKB:Q6NW13 xref: UniProtKB:Q8WTU4 xref: UniProtKB:Q95HL5 xref: UniProtKB:Q95HL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019685 ! RFX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015041 ! rfx3-traf2 physical interaction relationship: participates_in CCO:I0015759 ! rfx3-rfxdc1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028074 name: RFX2_HUMAN def: "DNA-binding protein RFX2" [UniProtKB:P48378] synonym: "Regulatory factor X 2" EXACT [UniProtKB:P48378] xref: EMBL:CAA53705.1 xref: UniProtKB:P48378 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019684 ! RFX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028081 name: A8K581_HUMAN def: "cDNA FLJ77125, highly similar to Homo sapiens regulatory factor X, 2 (influences HLA class II expression) (RFX2), transcript variant 2, mRNA" [UniProtKB:A8K581] xref: EMBL:BAF83885.1 xref: UniProtKB:A8K581 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028084 name: Q8SNA2_HUMAN def: "Regulatory factor X, 2 (Influences HLA class II expression)" [UniProtKB:Q8SNA2] xref: EMBL:AAH28579.1 xref: UniProtKB:Q8SNA2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0019684 ! RFX2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015277 ! rfx2-rfxdc1 physical interaction relationship: participates_in CCO:I0015417 ! mdfi-rfx2 physical interaction [Term] id: CCO:B0028088 name: Q5JTM3_HUMAN def: "Regulatory factor X, 3 (Influences HLA class II expression)" [UniProtKB:Q5JTM3] xref: EMBL:CAI41218.1 xref: UniProtKB:Q5JTM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019685 ! RFX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028140 name: VATL_HUMAN def: "V-type proton ATPase 16 kDa proteolipid subunit" [UniProtKB:P27449] synonym: "V-ATPase 16 kDa proteolipid subunit" EXACT [UniProtKB:P27449] synonym: "Vacuolar proton pump 16 kDa proteolipid subunit" EXACT [UniProtKB:P27449] xref: EMBL:AAA60039.1 xref: EMBL:AAH04537.1 xref: EMBL:AAH07389.1 xref: EMBL:AAH07759.1 xref: EMBL:AAH09290.1 xref: EMBL:AAP35819.1 xref: UniProtKB:P27449 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008345 ! ATP6V0C_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006277 ! hydrogen ion transporting ATP synthase activity, rotational mechanism relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000355 ! vacuole relationship: located_in CCO:C0000356 ! vacuolar membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: participates_in CCO:I0019195 ! lass2-atp6v0c physical interaction relationship: participates_in CCO:I0019334 ! hoct1-lass2-1 direct interaction [Term] id: CCO:B0028166 name: A1AT_HUMAN def: "Alpha-1-antitrypsin precursor" [UniProtKB:P01009] synonym: "Alpha-1 protease inhibitor" EXACT [UniProtKB:P01009] synonym: "Alpha-1-antiproteinase" EXACT [UniProtKB:P01009] xref: EMBL:AAA51545.1 xref: EMBL:AAA51546.1 xref: EMBL:AAA51547.1 xref: EMBL:AAB59369.1 xref: EMBL:AAB59370.1 xref: EMBL:AAB59371.1 xref: EMBL:AAB59375.1 xref: EMBL:AAB59495.1 xref: EMBL:AAF29581.1 xref: EMBL:AAG35496.1 xref: EMBL:AAH11991.1 xref: EMBL:AAH15642.1 xref: EMBL:AAV38262.1 xref: EMBL:ABG73380.1 xref: EMBL:BAG38005.1 xref: EMBL:CAA23755.1 xref: EMBL:CAA25838.1 xref: EMBL:CAA26677.1 xref: EMBL:CAD61914.1 xref: EMBL:CAD62306.1 xref: EMBL:CAD62334.1 xref: EMBL:CAD62585.1 xref: EMBL:CAJ15161.1 xref: UniProtKB:A6PX14 xref: UniProtKB:B2RDQ8 xref: UniProtKB:P01009 xref: UniProtKB:Q0PVP5 xref: UniProtKB:Q13672 xref: UniProtKB:Q53XB8 xref: UniProtKB:Q5U0M1 xref: UniProtKB:Q7M4R2 xref: UniProtKB:Q86U18 xref: UniProtKB:Q86U19 xref: UniProtKB:Q96BF9 xref: UniProtKB:Q96ES1 xref: UniProtKB:Q9P1P0 xref: UniProtKB:Q9UCE6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007191 ! SERPINA1_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:I0018559 ! serpina1-ela2-1 direct interaction [Term] id: CCO:B0028183 name: A8K5Y0_HUMAN def: "cDNA FLJ77554, highly similar to Homo sapiens regulatory factor X, 4 (influences HLA class II expression) (RFX4), transcript variant 3, mRNA" [UniProtKB:A8K5Y0] synonym: "Regulatory factor X, 4 (Influences HLA class II expression), isoform CRA_a" EXACT [UniProtKB:A8K5Y0] xref: EMBL:BAF84134.1 xref: EMBL:EAW97782.1 xref: UniProtKB:A8K5Y0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019686 ! RFX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0028186 name: ARP2_HUMAN def: "Actin-related protein 2" [UniProtKB:P61160] synonym: "Actin-like protein 2" EXACT [UniProtKB:P61160] xref: EMBL:AAB64187.1 xref: EMBL:AAH14546.1 xref: UniProtKB:O15142 xref: UniProtKB:P61160 xref: UniProtKB:Q96C82 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022049 ! ACTR2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000443 ! Arp2/3 protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0028201 name: OR1D2_HUMAN def: "Olfactory receptor 1D2" [UniProtKB:P34982] synonym: "Olfactory receptor 17-4" EXACT [UniProtKB:P34982] synonym: "Olfactory receptor OR17-6" EXACT [UniProtKB:P34982] synonym: "Olfactory receptor-like protein HGMP07E" EXACT [UniProtKB:P34982] synonym: "OR17-4" EXACT [UniProtKB:P34982] xref: EMBL:AAA18343.1 xref: EMBL:AAC99554.1 xref: EMBL:AAF37310.1 xref: EMBL:AAH69552.1 xref: EMBL:AAI06736.1 xref: EMBL:AAI06737.1 xref: EMBL:AAK95020.1 xref: EMBL:CAA46687.1 xref: EMBL:DAA04642.1 xref: UniProtKB:P34982 xref: UniProtKB:Q6IFL8 xref: UniProtKB:Q96RA4 xref: UniProtKB:Q9UM78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019061 ! OR1D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0028205 name: Q6IFM2_HUMAN def: "Olfactory receptor OR17-1" [UniProtKB:Q6IFM2] xref: EMBL:DAA04638.1 xref: UniProtKB:Q6IFM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0028206 name: Q6IFL7_HUMAN def: "Olfactory receptor OR17-2" [UniProtKB:Q6IFL7] xref: EMBL:DAA04643.1 xref: UniProtKB:Q6IFL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0028238 name: ROA0_HUMAN def: "Heterogeneous nuclear ribonucleoprotein A0" [UniProtKB:Q13151] synonym: "hnRNP A0" EXACT [UniProtKB:Q13151] xref: EMBL:AAA65094.1 xref: EMBL:AAH01008.1 xref: EMBL:AAH07271.1 xref: EMBL:AAH09284.1 xref: EMBL:AAH11972.1 xref: EMBL:AAH12980.1 xref: EMBL:AAH18949.1 xref: EMBL:AAH19271.1 xref: EMBL:AAH28976.1 xref: EMBL:AAH30249.1 xref: UniProtKB:Q13151 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014982 ! HNRNPA0_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: transforms_into CCO:B0052695 ! ROA0_HUMAN-Phosphoserine84 relationship: transforms_into CCO:B0052696 ! ROA0_HUMAN-Phosphotyrosine180 relationship: transforms_into CCO:B0052697 ! ROA0_HUMAN-Omega-N-methylated arginine291 [Term] id: CCO:B0028239 name: ROA3_HUMAN def: "Heterogeneous nuclear ribonucleoprotein A3" [UniProtKB:P51991] synonym: "hnRNP A3" EXACT [UniProtKB:P51991] xref: EMBL:AAI12028.1 xref: EMBL:AAI13471.1 xref: EMBL:AAQ63629.1 xref: EMBL:AAY14709.1 xref: UniProtKB:P51991 xref: UniProtKB:Q53RW7 xref: UniProtKB:Q6URK5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014984 ! HNRNPA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: transforms_into CCO:B0052698 ! ROA3_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0052699 ! ROA3_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0052700 ! ROA3_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0052701 ! ROA3_HUMAN-Phosphoserine358 relationship: transforms_into CCO:B0052702 ! ROA3_HUMAN-Phosphotyrosine360 relationship: transforms_into CCO:B0052703 ! ROA3_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0052704 ! ROA3_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0070120 ! ROA3_HUMAN-Phosphoserine366 [Term] id: CCO:B0028281 name: ARL1_HUMAN def: "ADP-ribosylation factor-like protein 1" [UniProtKB:P40616] xref: EMBL:AAC37567.1 xref: EMBL:AAH07000.1 xref: EMBL:AAM12601.1 xref: UniProtKB:P40616 xref: UniProtKB:P80417 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007265 ! ARL1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0028285 name: SEP13_HUMAN def: "Septin-13" [UniProtKB:A8MT51] synonym: "Septin-7B" EXACT [UniProtKB:A8MT51] xref: UniProtKB:A8MT51 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014365 ! SEPT13_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0028290 name: JAG1_HUMAN def: "Protein jagged-1 precursor" [UniProtKB:P78504] synonym: "CD339 antigen" EXACT [UniProtKB:P78504] synonym: "hJ1" EXACT [UniProtKB:P78504] synonym: "Jagged1" EXACT [UniProtKB:P78504] xref: EMBL:AAB39007.1 xref: EMBL:AAB84053.1 xref: EMBL:AAC51323.1 xref: EMBL:AAC51731.1 xref: EMBL:AAC52020.1 xref: EMBL:AAI26206.1 xref: EMBL:AAI26208.1 xref: EMBL:CAC07198.1 xref: UniProtKB:A0AV43 xref: UniProtKB:O14902 xref: UniProtKB:O15122 xref: UniProtKB:P78504 xref: UniProtKB:Q15816 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011497 ! JAG1_human relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: participates_in CCO:P0002453 ! positive regulation of myeloid cell differentiation relationship: participates_in CCO:P0002535 ! positive regulation of Notch signaling pathway [Term] id: CCO:B0028291 name: DLL4_HUMAN def: "Delta-like protein 4 precursor" [UniProtKB:Q9NR61] synonym: "Delta4" EXACT [UniProtKB:Q9NR61] synonym: "Drosophila Delta homolog 4" EXACT [UniProtKB:Q9NR61] xref: EMBL:AAF76427.1 xref: EMBL:AAF81912.1 xref: EMBL:AAI06951.1 xref: EMBL:AAQ89253.1 xref: EMBL:BAB16085.1 xref: EMBL:BAB18581.1 xref: UniProtKB:Q3KP23 xref: UniProtKB:Q9NQT9 xref: UniProtKB:Q9NR61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011353 ! DLL4_human relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0028292 name: DLL1_HUMAN def: "Delta-like protein 1 precursor" [UniProtKB:O00548] synonym: "Delta1" EXACT [UniProtKB:O00548] synonym: "Drosophila Delta homolog 1" EXACT [UniProtKB:O00548] synonym: "H-Delta-1" EXACT [UniProtKB:O00548] xref: EMBL:AAB61286.1 xref: EMBL:AAF05834.1 xref: EMBL:AAG09716.1 xref: EMBL:AAQ89251.1 xref: EMBL:CAB89569.1 xref: UniProtKB:O00548 xref: UniProtKB:Q9NU41 xref: UniProtKB:Q9UJV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011352 ! DLL1_human relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: participates_in CCO:P0002422 ! negative regulation of auditory receptor cell differentiation [Term] id: CCO:B0028295 name: A8MSJ8_HUMAN def: "Putative uncharacterized protein MYC (V-myc myelocytomatosis viral oncogene homolog (Avian), isoform CRA_b)" [UniProtKB:A8MSJ8] xref: EMBL:EAW92099.1 xref: UniProtKB:A8MSJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005142 ! MYC_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0028314 name: TIG3_HUMAN def: "Retinoic acid receptor responder protein 3" [UniProtKB:Q9UL19] synonym: "RAR-responsive protein TIG3" EXACT [UniProtKB:Q9UL19] synonym: "Retinoid-inducible gene 1 protein" EXACT [UniProtKB:Q9UL19] synonym: "Tazarotene-induced gene 3 protein" EXACT [UniProtKB:Q9UL19] xref: EMBL:AAC84000.1 xref: EMBL:AAF02294.1 xref: EMBL:AAH09678.1 xref: EMBL:BAB08109.1 xref: UniProtKB:O95200 xref: UniProtKB:Q9UL19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008294 ! RARRES3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0028319 name: NEK3_HUMAN def: "Serine/threonine-protein kinase Nek3" [UniProtKB:P51956] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P51956] synonym: "HSPK 36" EXACT [UniProtKB:P51956] synonym: "NimA-related protein kinase 3" EXACT [UniProtKB:P51956] xref: EMBL:AAH19916.2 xref: EMBL:BAC15599.1 xref: EMBL:BAF82948.1 xref: EMBL:CAA80921.1 xref: EMBL:CAA82310.1 xref: EMBL:CAI12895.1 xref: EMBL:EAX08907.1 xref: UniProtKB:A8K2J4 xref: UniProtKB:P51956 xref: UniProtKB:Q5TAP2 xref: UniProtKB:Q8J023 xref: UniProtKB:Q8WUN5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007871 ! NEK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018005 ! nek3-vav2-2 physical interaction relationship: participates_in CCO:I0018778 ! nek3-prlr-1 physical interaction relationship: participates_in CCO:I0018779 ! nek3-vav2-3 physical interaction relationship: participates_in CCO:I0018781 ! nek3-vav2-1 physical interaction relationship: transforms_into CCO:B0035259 ! NEK3_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0035260 ! NEK3_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0035261 ! NEK3_HUMAN-Phosphothreonine402 relationship: transforms_into CCO:B0035262 ! NEK3_HUMAN-Phosphothreonine479 [Term] id: CCO:B0028327 name: G3BP2_HUMAN def: "Ras GTPase-activating protein-binding protein 2" [UniProtKB:Q9UN86] synonym: "G3BP-2" EXACT [UniProtKB:Q9UN86] synonym: "GAP SH3 domain-binding protein 2" EXACT [UniProtKB:Q9UN86] xref: EMBL:AAC15705.1 xref: EMBL:AAC95292.1 xref: EMBL:AAD51932.1 xref: EMBL:AAH11731.1 xref: EMBL:BAA31635.2 xref: UniProtKB:O60606 xref: UniProtKB:O75149 xref: UniProtKB:Q9UN86 xref: UniProtKB:Q9UPA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007570 ! G3BP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000771 ! cytoplasmic sequestering of NF-kappaB relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0034824 ! G3BP2_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0034825 ! G3BP2_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0034826 ! G3BP2_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0034827 ! G3BP2_HUMAN-Phosphothreonine227 relationship: transforms_into CCO:B0034828 ! G3BP2_HUMAN-Omega-N-methylated arginine457 relationship: transforms_into CCO:B0034829 ! G3BP2_HUMAN-Omega-N-methylated arginine468 relationship: transforms_into CCO:B0066340 ! G3BP2_HUMAN-Phosphoserine235 [Term] id: CCO:B0028328 name: G3BP1_HUMAN def: "Ras GTPase-activating protein-binding protein 1" [UniProtKB:Q13283] synonym: "ATP-dependent DNA helicase VIII" EXACT [UniProtKB:Q13283] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q13283] synonym: "G3BP-1" EXACT [UniProtKB:Q13283] synonym: "GAP SH3 domain-binding protein 1" EXACT [UniProtKB:Q13283] synonym: "HDH-VIII" EXACT [UniProtKB:Q13283] xref: EMBL:AAB07787.1 xref: EMBL:AAH06997.1 xref: UniProtKB:Q13283 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007569 ! G3BP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0034815 ! G3BP1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0034816 ! G3BP1_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0034817 ! G3BP1_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0034818 ! G3BP1_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0034819 ! G3BP1_HUMAN-Phosphothreonine268 relationship: transforms_into CCO:B0034820 ! G3BP1_HUMAN-Omega-N-methylated arginine435 relationship: transforms_into CCO:B0034821 ! G3BP1_HUMAN-Omega-N-methylated arginine447 relationship: transforms_into CCO:B0034822 ! G3BP1_HUMAN-Omega-N-methylated arginine460 relationship: transforms_into CCO:B0034823 ! G3BP1_HUMAN-Omega-N-methylated arginine465 relationship: transforms_into CCO:B0066338 ! G3BP1_HUMAN-Phosphothreonine143 relationship: transforms_into CCO:B0066339 ! G3BP1_HUMAN-Phosphoserine373 [Term] id: CCO:B0028341 name: Q59GI1_HUMAN def: "Serum response factor (C-fos serum response element-binding transcription factor) variant" [UniProtKB:Q59GI1] xref: EMBL:BAD92365.1 xref: UniProtKB:Q59GI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0028347 name: SRF_HUMAN def: "Serum response factor" [UniProtKB:P11831] synonym: "SRF" EXACT [UniProtKB:P11831] xref: EMBL:AAA36647.1 xref: EMBL:AAH48211.1 xref: EMBL:AAH52572.1 xref: EMBL:CAI13785.1 xref: EMBL:CAI20207.1 xref: EMBL:EAX04161.1 xref: UniProtKB:P11831 xref: UniProtKB:Q5T648 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008223 ! SRF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017672 ! mkl2-srf-1 physical interaction relationship: participates_in CCO:I0018303 ! srf-mkl2-1 physical interaction relationship: participates_in CCO:I0018304 ! srf-mkl1-1 physical interaction relationship: participates_in CCO:I0019352 ! srf-myocd-1 physical interaction relationship: participates_in CCO:I0019353 ! srf-myocd-2 physical interaction relationship: participates_in CCO:I0019354 ! srf-mlk1-1 physical interaction relationship: participates_in CCO:I0019355 ! srf-mlk2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0035681 ! SRF_HUMAN-Phosphotyrosine76 relationship: transforms_into CCO:B0035682 ! SRF_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0035683 ! SRF_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0035684 ! SRF_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0035685 ! SRF_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0035686 ! SRF_HUMAN-Phosphoserine103 relationship: transforms_into CCO:B0035687 ! SRF_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0035688 ! SRF_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0035689 ! SRF_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0035690 ! SRF_HUMAN-Phosphoserine446 [Term] id: CCO:B0028354 name: ETV6_HUMAN def: "Transcription factor ETV6" [UniProtKB:P41212] synonym: "ETS translocation variant 6" EXACT [UniProtKB:P41212] synonym: "ETS-related protein Tel1" EXACT [UniProtKB:P41212] synonym: "Tel" EXACT [UniProtKB:P41212] xref: EMBL:AAA19786.1 xref: EMBL:AAB17134.1 xref: EMBL:AAB17135.1 xref: EMBL:AAC50690.1 xref: EMBL:AAH43399.1 xref: EMBL:ABI30005.1 xref: UniProtKB:A3QVP6 xref: UniProtKB:P41212 xref: UniProtKB:Q9UMF6 xref: UniProtKB:Q9UMF7 xref: UniProtKB:Q9UMG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007507 ! ETV6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0034768 ! ETV6_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0034769 ! ETV6_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0065171 ! ETV6_HUMAN-Phosphothreonine18 [Term] id: CCO:B0028502 name: ERCC3_HUMAN def: "TFIIH basal transcription factor complex helicase XPB subunit" [UniProtKB:P19447] synonym: "Basic transcription factor 2 89 kDa subunit" EXACT [UniProtKB:P19447] synonym: "BTF2-p89" EXACT [UniProtKB:P19447] synonym: "DNA excision repair protein ERCC-3" EXACT [UniProtKB:P19447] synonym: "DNA repair protein complementing XP-B cells" EXACT [UniProtKB:P19447] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P19447] synonym: "TFIIH 89 kDa subunit" EXACT [UniProtKB:P19447] synonym: "Xeroderma pigmentosum group B-complementing protein" EXACT [UniProtKB:P19447] xref: EMBL:AAA52396.1 xref: EMBL:AAH08820.1 xref: EMBL:AAN46739.1 xref: UniProtKB:P19447 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010893 ! ERCC3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0005800 ! 3'-5' DNA helicase activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000279 ! holo TFIIH complex relationship: participates_in CCO:P0000006 ! cell cycle checkpoint relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0036002 ! ERCC3_HUMAN-Phosphoserine370 [Term] id: CCO:B0028510 name: MYBA_HUMAN def: "Myb-related protein A" [UniProtKB:P10243] synonym: "A-Myb" EXACT [UniProtKB:P10243] xref: EMBL:CAA31656.1 xref: EMBL:CAA46886.1 xref: UniProtKB:P10243 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018688 ! MYBL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028526 name: A8MXH7_HUMAN def: "Putative uncharacterized protein MYBL2" [UniProtKB:A8MXH7] xref: UniProtKB:A8MXH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005139 ! MYBL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028528 name: Q495F9_HUMAN def: "V-myb myeloblastosis viral oncogene homolog (Avian)-like 1" [UniProtKB:Q495F9] synonym: "HCG18392, isoform CRA_b" EXACT [UniProtKB:Q495F9] xref: EMBL:AAI01189.1 xref: EMBL:EAW86912.1 xref: UniProtKB:Q495F9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018688 ! MYBL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028530 name: Q5THS6_HUMAN def: "V-myb myeloblastosis viral oncogene homolog (Avian)" [UniProtKB:Q5THS6] xref: EMBL:CAI20198.1 xref: UniProtKB:Q5THS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005140 ! MYB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028532 name: Q708E2_HUMAN def: "C-myb v-myb myeloblastosis viral oncogene homologue (avian), exon 1 and joined CDS" [UniProtKB:Q708E2] xref: EMBL:CAF04484.1 xref: UniProtKB:Q708E2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0028579 name: Q9H1R6_HUMAN def: "BCL2-like 1" [UniProtKB:Q9H1R6] xref: EMBL:CAC10003.1 xref: UniProtKB:Q9H1R6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004155 ! BCL2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0028580 name: Q5QP56_HUMAN def: "BCL2-like 1" [UniProtKB:Q5QP56] xref: EMBL:CAI12813.1 xref: UniProtKB:Q5QP56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004155 ! BCL2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0028581 name: Q5QP59_HUMAN def: "BCL2-like 1" [UniProtKB:Q5QP59] xref: EMBL:CAI12815.1 xref: UniProtKB:Q5QP59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004155 ! BCL2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0028582 name: Q5TE64_HUMAN def: "BCL2-like 1" [UniProtKB:Q5TE64] xref: EMBL:CAI12812.1 xref: EMBL:CAI23026.1 xref: UniProtKB:Q5TE64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004155 ! BCL2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0028585 name: BCLW_HUMAN def: "Apoptosis regulator Bcl-W" [UniProtKB:Q92843] synonym: "Bcl-2-like 2 protein" EXACT [UniProtKB:Q92843] xref: EMBL:AAB09055.1 xref: EMBL:AAH21198.1 xref: EMBL:AAI04790.1 xref: EMBL:AAI13523.1 xref: EMBL:AAV38356.1 xref: EMBL:BAA19666.2 xref: UniProtKB:Q2M3U0 xref: UniProtKB:Q5U0H4 xref: UniProtKB:Q92843 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017141 ! BCL2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017889 ! pmaip1-bclw-1 direct interaction relationship: participates_in CCO:I0019270 ! bim-bclw-2 direct interaction relationship: participates_in CCO:I0019271 ! bbc3-bclw-1 direct interaction relationship: participates_in CCO:I0019272 ! bad-bclw-1 direct interaction relationship: participates_in CCO:I0019273 ! bik-bclw-2 direct interaction relationship: participates_in CCO:I0019274 ! hrk-bclw-1 direct interaction relationship: participates_in CCO:I0019275 ! bid-bclw-2 direct interaction relationship: participates_in CCO:I0019464 ! bcl2l2-bid direct interaction relationship: participates_in CCO:I0019469 ! bcl2l2-bik direct interaction relationship: participates_in CCO:I0019470 ! bcl2l2-bbc3 direct interaction relationship: participates_in CCO:I0019505 ! pmaip1-bclw-2 direct interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0063865 ! BCLW_HUMAN-Phosphoserine192 [Term] id: CCO:B0028600 name: APOA1_HUMAN def: "Apolipoprotein A-I precursor" [UniProtKB:P02647] synonym: "Apo-AI" EXACT [UniProtKB:P02647] synonym: "ApoA-I" EXACT [UniProtKB:P02647] xref: EMBL:AAA35545.1 xref: EMBL:AAA51747.1 xref: EMBL:AAA62829.1 xref: EMBL:AAB59514.1 xref: EMBL:AAH05380.1 xref: EMBL:AAI10287.1 xref: EMBL:AAQ91811.1 xref: EMBL:AAS68227.1 xref: EMBL:CAA01198.1 xref: EMBL:CAA25232.1 xref: EMBL:CAA25519.1 xref: EMBL:CAA26097.1 xref: EMBL:CAA30377.1 xref: UniProtKB:P02647 xref: UniProtKB:Q6LDN9 xref: UniProtKB:Q6Q785 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016991 ! APOA1_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0003584 ! cholesterol transporter activity relationship: has_function CCO:F0005528 ! apolipoprotein receptor binding relationship: has_function CCO:F0005529 ! apolipoprotein A-I receptor binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008244 ! phosphatidylcholine-sterol O-acyltransferase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0002144 ! high-density lipoprotein particle relationship: participates_in CCO:I0015960 ! app-apoa-5 physical interaction relationship: participates_in CCO:I0016124 ! app-apoa1-1 physical interaction relationship: participates_in CCO:I0016311 ! app-apoa1-3 physical interaction relationship: participates_in CCO:I0018674 ! app-apoa1-2 physical interaction relationship: participates_in CCO:I0019267 ! app-apoa-6 physical interaction relationship: participates_in CCO:I0020482 ! tnfrsf10c-apoa1 physical interaction relationship: participates_in CCO:I0020487 ! tomm20-apoa1 physical interaction relationship: participates_in CCO:I0020618 ! pcmt1-apoa1 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001634 ! Cdc42 protein signal transduction relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0028618 name: KS6A3_HUMAN def: "Ribosomal protein S6 kinase alpha-3" [UniProtKB:P51812] synonym: "90 kDa ribosomal protein S6 kinase 3" EXACT [UniProtKB:P51812] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P51812] synonym: "Insulin-stimulated protein kinase 1" EXACT [UniProtKB:P51812] synonym: "ISPK-1" EXACT [UniProtKB:P51812] synonym: "MAP kinase-activated protein kinase 1b" EXACT [UniProtKB:P51812] synonym: "MAPKAPK1B" EXACT [UniProtKB:P51812] synonym: "p90-RSK 3" EXACT [UniProtKB:P51812] synonym: "pp90RSK2" EXACT [UniProtKB:P51812] synonym: "Ribosomal S6 kinase 2" EXACT [UniProtKB:P51812] synonym: "RSK-2" EXACT [UniProtKB:P51812] synonym: "S6K-alpha 3" EXACT [UniProtKB:P51812] xref: EMBL:AAA81952.1 xref: EMBL:AAC82495.1 xref: EMBL:AAH96301.1 xref: EMBL:AAH96302.1 xref: EMBL:AAH96303.1 xref: EMBL:BAC81131.1 xref: EMBL:BAD92170.1 xref: EMBL:CAI39687.1 xref: EMBL:CAI40548.1 xref: UniProtKB:P51812 xref: UniProtKB:Q4VAP3 xref: UniProtKB:Q59H26 xref: UniProtKB:Q5JPK8 xref: UniProtKB:Q7Z3Z7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018442 ! RPS6KA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0067464 ! KS6A3_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0067465 ! KS6A3_HUMAN-Phosphothreonine231 relationship: transforms_into CCO:B0067466 ! KS6A3_HUMAN-Phosphothreonine365 relationship: transforms_into CCO:B0067467 ! KS6A3_HUMAN-Phosphoserine369 relationship: transforms_into CCO:B0067468 ! KS6A3_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0067469 ! KS6A3_HUMAN-Phosphoserine386 relationship: transforms_into CCO:B0067470 ! KS6A3_HUMAN-Phosphothreonine577 relationship: transforms_into CCO:B0067471 ! KS6A3_HUMAN-Phosphoserine715 relationship: transforms_into CCO:B0067472 ! KS6A3_HUMAN-Phosphoserine737 [Term] id: CCO:B0028620 name: KS6A6_HUMAN def: "Ribosomal protein S6 kinase alpha-6" [UniProtKB:Q9UK32] synonym: "90 kDa ribosomal protein S6 kinase 6" EXACT [UniProtKB:Q9UK32] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UK32] synonym: "p90-RSK 6" EXACT [UniProtKB:Q9UK32] synonym: "pp90RSK4" EXACT [UniProtKB:Q9UK32] synonym: "Ribosomal S6 kinase 4" EXACT [UniProtKB:Q9UK32] synonym: "RSK-4" EXACT [UniProtKB:Q9UK32] synonym: "S6K-alpha 6" EXACT [UniProtKB:Q9UK32] xref: EMBL:AAF13190.1 xref: EMBL:CAC16111.2 xref: EMBL:CAD13486.2 xref: EMBL:CAG38803.1 xref: UniProtKB:Q6FHX2 xref: UniProtKB:Q8WX28 xref: UniProtKB:Q9H4S6 xref: UniProtKB:Q9UK32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018444 ! RPS6KA6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020442 ! rps6ka6-nr4a1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0067481 ! KS6A6_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0067482 ! KS6A6_HUMAN-Phosphothreonine368 relationship: transforms_into CCO:B0067483 ! KS6A6_HUMAN-Phosphoserine372 relationship: transforms_into CCO:B0067484 ! KS6A6_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0067485 ! KS6A6_HUMAN-Phosphothreonine581 relationship: transforms_into CCO:B0067486 ! KS6A6_HUMAN-Phosphoserine742 [Term] id: CCO:B0028627 name: KS6A1_HUMAN def: "Ribosomal protein S6 kinase alpha-1" [UniProtKB:Q15418] synonym: "90 kDa ribosomal protein S6 kinase 1" EXACT [UniProtKB:Q15418] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q15418] synonym: "MAP kinase-activated protein kinase 1a" EXACT [UniProtKB:Q15418] synonym: "MAPKAPK1A" EXACT [UniProtKB:Q15418] synonym: "p90-RSK 1" EXACT [UniProtKB:Q15418] synonym: "p90S6K" EXACT [UniProtKB:Q15418] synonym: "pp90RSK1" EXACT [UniProtKB:Q15418] synonym: "Ribosomal S6 kinase 1" EXACT [UniProtKB:Q15418] synonym: "RSK-1" EXACT [UniProtKB:Q15418] synonym: "S6K-alpha 1" EXACT [UniProtKB:Q15418] xref: EMBL:AAC82497.1 xref: EMBL:AAH14966.1 xref: EMBL:CAC36348.1 xref: EMBL:CAI14647.1 xref: EMBL:CAI14648.1 xref: EMBL:CAI14649.1 xref: UniProtKB:Q15418 xref: UniProtKB:Q5SVM5 xref: UniProtKB:Q5SVM8 xref: UniProtKB:Q5SVM9 xref: UniProtKB:Q96C05 xref: UniProtKB:Q9BQK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018440 ! RPS6KA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018693 ! rps6ka1-creb1-1 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0067449 ! KS6A1_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0067450 ! KS6A1_HUMAN-Phosphothreonine225 relationship: transforms_into CCO:B0067451 ! KS6A1_HUMAN-Phosphothreonine348 relationship: transforms_into CCO:B0067452 ! KS6A1_HUMAN-Phosphothreonine359 relationship: transforms_into CCO:B0067453 ! KS6A1_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0067454 ! KS6A1_HUMAN-Phosphoserine369 relationship: transforms_into CCO:B0067455 ! KS6A1_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0067456 ! KS6A1_HUMAN-Phosphothreonine573 relationship: transforms_into CCO:B0067457 ! KS6A1_HUMAN-Phosphoserine732 [Term] id: CCO:B0028628 name: Q7Z721_HUMAN def: "RPS6KB1 protein" [UniProtKB:Q7Z721] synonym: "Ribosomal protein S6 kinase, 70kDa, polypeptide 1, isoform CRA_c" EXACT [UniProtKB:Q7Z721] xref: EMBL:AAH53365.1 xref: EMBL:EAW94384.1 xref: UniProtKB:Q7Z721 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018445 ! RPS6KB1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000407 ! ribosome relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0028633 name: KS6B1_HUMAN def: "Ribosomal protein S6 kinase beta-1" [UniProtKB:P23443] synonym: "70 kDa ribosomal protein S6 kinase 1" EXACT [UniProtKB:P23443] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P23443] synonym: "p70 S6 kinase alpha" EXACT [UniProtKB:P23443] synonym: "p70(S6K)-alpha" EXACT [UniProtKB:P23443] synonym: "p70-alpha" EXACT [UniProtKB:P23443] synonym: "p70-S6K" EXACT [UniProtKB:P23443] synonym: "P70S6K" EXACT [UniProtKB:P23443] synonym: "Ribosomal protein S6 kinase I" EXACT [UniProtKB:P23443] synonym: "S6K" EXACT [UniProtKB:P23443] synonym: "S6K1" EXACT [UniProtKB:P23443] xref: EMBL:AAA36410.1 xref: EMBL:AAA36411.1 xref: UniProtKB:P23443 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018445 ! RPS6KB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067487 ! KS6B1_HUMAN-Phosphoserine441 relationship: transforms_into CCO:B0067488 ! KS6B1_HUMAN-Phosphothreonine444 relationship: transforms_into CCO:B0067489 ! KS6B1_HUMAN-Phosphoserine447 [Term] id: CCO:B0028634 name: KS6A2_HUMAN def: "Ribosomal protein S6 kinase alpha-2" [UniProtKB:Q15349] synonym: "90 kDa ribosomal protein S6 kinase 2" EXACT [UniProtKB:Q15349] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q15349] synonym: "MAP kinase-activated protein kinase 1c" EXACT [UniProtKB:Q15349] synonym: "MAPKAPK1C" EXACT [UniProtKB:Q15349] synonym: "p90-RSK 2" EXACT [UniProtKB:Q15349] synonym: "pp90RSK3" EXACT [UniProtKB:Q15349] synonym: "Ribosomal S6 kinase 3" EXACT [UniProtKB:Q15349] synonym: "RSK-3" EXACT [UniProtKB:Q15349] synonym: "S6K-alpha 2" EXACT [UniProtKB:Q15349] xref: EMBL:AAC82496.1 xref: EMBL:AAH02363.1 xref: EMBL:BAD92353.1 xref: EMBL:CAA59427.1 xref: EMBL:CAI19651.1 xref: EMBL:CAI20579.1 xref: UniProtKB:Q15349 xref: UniProtKB:Q15419 xref: UniProtKB:Q59GJ3 xref: UniProtKB:Q5TI68 xref: UniProtKB:Q96J38 xref: UniProtKB:Q9UJN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018441 ! RPS6KA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0067458 ! KS6A2_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0067459 ! KS6A2_HUMAN-Phosphothreonine356 relationship: transforms_into CCO:B0067460 ! KS6A2_HUMAN-Phosphoserine360 relationship: transforms_into CCO:B0067461 ! KS6A2_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0067462 ! KS6A2_HUMAN-Phosphothreonine570 relationship: transforms_into CCO:B0067463 ! KS6A2_HUMAN-Phosphoserine730 [Term] id: CCO:B0028635 name: A6NGG4_HUMAN def: "Putative uncharacterized protein RPS6KA1" [UniProtKB:A6NGG4] xref: UniProtKB:A6NGG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018440 ! RPS6KA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0028677 name: PADI4_HUMAN def: "Protein-arginine deiminase type-4" [UniProtKB:Q9UM07] synonym: "EC 3.5.3.15" EXACT [UniProtKB:Q9UM07] synonym: "HL-60 PAD" EXACT [UniProtKB:Q9UM07] synonym: "Peptidylarginine deiminase IV" EXACT [UniProtKB:Q9UM07] synonym: "Protein-arginine deiminase type IV" EXACT [UniProtKB:Q9UM07] xref: EMBL:AAH25718.1 xref: EMBL:BAA84542.1 xref: EMBL:CAE47743.1 xref: EMBL:CAH73167.1 xref: UniProtKB:Q5VTZ8 xref: UniProtKB:Q70SX4 xref: UniProtKB:Q9UM07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019287 ! PADI4_human relationship: has_function CCO:F0001041 ! protein-arginine deiminase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0028704 name: A8MX32_HUMAN def: "Putative uncharacterized protein RFC3" [UniProtKB:A8MX32] xref: UniProtKB:A8MX32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008078 ! RFC3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0028736 name: CDYL1_HUMAN def: "Chromodomain Y-like protein" [UniProtKB:Q9Y232] synonym: "CDY-like" EXACT [UniProtKB:Q9Y232] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q9Y232] xref: EMBL:AAD22734.1 xref: EMBL:AAD22735.1 xref: EMBL:AAH61516.1 xref: EMBL:AAI08726.1 xref: EMBL:AAI19683.1 xref: EMBL:CAB43304.1 xref: EMBL:CAC36888.2 xref: EMBL:CAH73737.1 xref: EMBL:CAI20892.1 xref: UniProtKB:Q0VDG7 xref: UniProtKB:Q32NC5 xref: UniProtKB:Q5VX99 xref: UniProtKB:Q6P7T5 xref: UniProtKB:Q9BWZ2 xref: UniProtKB:Q9Y232 xref: UniProtKB:Q9Y424 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007370 ! CDYL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0034639 ! CDYL1_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0034640 ! CDYL1_HUMAN-Phosphoserine201 [Term] id: CCO:B0028758 name: SPTC1_HUMAN def: "Serine palmitoyltransferase 1" [UniProtKB:O15269] synonym: "EC 2.3.1.50" EXACT [UniProtKB:O15269] synonym: "LCB 1" EXACT [UniProtKB:O15269] synonym: "Long chain base biosynthesis protein 1" EXACT [UniProtKB:O15269] synonym: "Serine-palmitoyl-CoA transferase 1" EXACT [UniProtKB:O15269] synonym: "SPT 1" EXACT [UniProtKB:O15269] synonym: "SPT1" EXACT [UniProtKB:O15269] xref: EMBL:AAK29328.1 xref: EMBL:CAA69941.1 xref: EMBL:CAH69924.1 xref: EMBL:CAH70209.1 xref: UniProtKB:O15269 xref: UniProtKB:Q5VWB4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008222 ! SPTLC1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001122 ! serine C-palmitoyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003342 ! transferase activity, transferring nitrogenous groups relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction [Term] id: CCO:B0028774 name: PCBP1_HUMAN def: "Poly(rC)-binding protein 1" [UniProtKB:Q15365] synonym: "Alpha-CP1" EXACT [UniProtKB:Q15365] synonym: "hnRNP-E1" EXACT [UniProtKB:Q15365] synonym: "Nucleic acid-binding protein SUB2.3" EXACT [UniProtKB:Q15365] xref: EMBL:AAA91317.1 xref: EMBL:AAH39742.1 xref: EMBL:CAA55016.1 xref: EMBL:CAA82631.1 xref: UniProtKB:Q13157 xref: UniProtKB:Q14975 xref: UniProtKB:Q15365 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007953 ! PCBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016188 ! pcbp1-tsc22d4 physical interaction relationship: participates_in CCO:I0017580 ! ewsr1-pcbp1 physical interaction relationship: participates_in CCO:I0019151 ! pcbp1-tsc22d4-1 physical interaction relationship: participates_in CCO:I0019152 ! pcbp1-hnrpk physical interaction relationship: transforms_into CCO:B0035343 ! PCBP1_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0035344 ! PCBP1_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0035345 ! PCBP1_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0035346 ! PCBP1_HUMAN-Phosphoserine262 relationship: transforms_into CCO:B0035347 ! PCBP1_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0035348 ! PCBP1_HUMAN-Phosphoserine264 [Term] id: CCO:B0028808 name: MCLN1_HUMAN def: "Mucolipin-1" [UniProtKB:Q9GZU1] synonym: "MG-2" EXACT [UniProtKB:Q9GZU1] synonym: "Mucolipidin" EXACT [UniProtKB:Q9GZU1] xref: EMBL:AAG00797.1 xref: EMBL:AAG00798.1 xref: EMBL:AAG10422.1 xref: EMBL:AAG42242.1 xref: EMBL:AAH05149.1 xref: EMBL:AAQ13604.1 xref: EMBL:BAB15360.1 xref: EMBL:CAC07813.1 xref: EMBL:CAC08215.1 xref: UniProtKB:Q7Z4F7 xref: UniProtKB:Q9GZU1 xref: UniProtKB:Q9H292 xref: UniProtKB:Q9H4B3 xref: UniProtKB:Q9H4B5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022391 ! MCOLN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020365 ! mcoln1-rfp physical interaction relationship: transforms_into CCO:B0068059 ! MCLN1_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0068060 ! MCLN1_HUMAN-Phosphothreonine34 relationship: transforms_into CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 [Term] id: CCO:B0028895 name: RL29_HUMAN def: "60S ribosomal protein L29" [UniProtKB:P47914] synonym: "Cell surface heparin-binding protein HIP" EXACT [UniProtKB:P47914] xref: EMBL:AAC50499.1 xref: EMBL:AAC50647.1 xref: EMBL:AAH08926.1 xref: EMBL:AAH70190.1 xref: EMBL:AAH70481.1 xref: EMBL:AAH71663.1 xref: EMBL:CAA89008.1 xref: UniProtKB:P47914 xref: UniProtKB:Q6IPY3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022575 ! RPL29_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019816 ! rpl29-chd3 physical interaction relationship: transforms_into CCO:B0070080 ! RL29_HUMAN-N6-methyllysine5 relationship: transforms_into CCO:B0070081 ! RL29_HUMAN-Phosphoserine142 [Term] id: CCO:B0028910 name: Q9NWJ6_HUMAN def: "cDNA FLJ20805 fis, clone ADSE02009" [UniProtKB:Q9NWJ6] synonym: "Putative uncharacterized protein APBB1IP" EXACT [UniProtKB:Q9NWJ6] xref: EMBL:BAA91384.1 xref: UniProtKB:A6NNU4 xref: UniProtKB:Q9NWJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016871 ! APBB1IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0028914 name: AB1IP_HUMAN def: "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein" [UniProtKB:Q7Z5R6] synonym: "APBB1-interacting protein 1" EXACT [UniProtKB:Q7Z5R6] synonym: "PREL-1" EXACT [UniProtKB:Q7Z5R6] synonym: "Proline-rich EVH1 ligand 1" EXACT [UniProtKB:Q7Z5R6] synonym: "Proline-rich protein 73" EXACT [UniProtKB:Q7Z5R6] synonym: "Rap1-GTP-interacting adapter molecule" EXACT [UniProtKB:Q7Z5R6] synonym: "RARP-1" EXACT [UniProtKB:Q7Z5R6] synonym: "Retinoic acid-responsive proline-rich protein 1" EXACT [UniProtKB:Q7Z5R6] synonym: "RIAM" EXACT [UniProtKB:Q7Z5R6] xref: EMBL:AAH54516.1 xref: EMBL:AAN75525.1 xref: EMBL:BAC41256.1 xref: EMBL:CAH70339.1 xref: UniProtKB:Q7Z5R6 xref: UniProtKB:Q8IWS8 xref: UniProtKB:Q8IZZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016871 ! APBB1IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065264 ! AB1IP_HUMAN-Phosphoserine531 [Term] id: CCO:B0028938 name: EFS_HUMAN def: "Embryonal Fyn-associated substrate" [UniProtKB:O43281] synonym: "Cas scaffolding protein family member 3" EXACT [UniProtKB:O43281] synonym: "HEFS" EXACT [UniProtKB:O43281] xref: EMBL:AAH34246.1 xref: EMBL:BAA24588.1 xref: EMBL:BAA24589.1 xref: UniProtKB:O43281 xref: UniProtKB:O43282 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007480 ! EFS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015560 ! efs-scam_1 physical interaction relationship: participates_in CCO:I0020256 ! bcar1-efs physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0034724 ! EFS_HUMAN-Phosphotyrosine253 [Term] id: CCO:B0029013 name: OR9I1_HUMAN def: "Olfactory receptor 9I1" [UniProtKB:Q8NGQ6] xref: EMBL:AAK95016.1 xref: EMBL:BAC05954.1 xref: UniProtKB:Q8NGQ6 xref: UniProtKB:Q96RA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014901 ! OR9I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029014 name: Q6IF62_HUMAN xref: UniProtKB:Q6IF62 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029015 name: OR5W2_HUMAN def: "Olfactory receptor 5W2" [UniProtKB:Q8NH69] synonym: "Olfactory receptor OR11-155" EXACT [UniProtKB:Q8NH69] xref: EMBL:BAC05768.1 xref: EMBL:DAA04796.1 xref: UniProtKB:Q8NH69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014886 ! OR5W2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029017 name: OR5B3_HUMAN def: "Olfactory receptor 5B3" [UniProtKB:Q8NH48] synonym: "Olfactory receptor OR11-239" EXACT [UniProtKB:Q8NH48] xref: EMBL:BAC05790.1 xref: EMBL:DAA04904.1 xref: UniProtKB:Q6IEV6 xref: UniProtKB:Q8NH48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014879 ! OR5B3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029019 name: Q8NH91_HUMAN def: "Seven transmembrane helix receptor (HCG2040518)" [UniProtKB:Q8NH91] xref: EMBL:BAC05746.1 xref: EMBL:EAW73793.1 xref: UniProtKB:Q8NH91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015241 ! hCG_2040518_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029022 name: OR8K5_HUMAN def: "Olfactory receptor 8K5" [UniProtKB:Q8NH50] xref: EMBL:BAC05787.1 xref: UniProtKB:Q8NH50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014896 ! OR8K5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029023 name: OR5L1_HUMAN def: "Olfactory receptor 5L1" [UniProtKB:Q8NGL2] synonym: "Olfactory receptor OR11-151" EXACT [UniProtKB:Q8NGL2] synonym: "OST262" EXACT [UniProtKB:Q8NGL2] xref: EMBL:AAI09250.1 xref: EMBL:AAI09251.1 xref: EMBL:BAC06000.1 xref: EMBL:DAA04730.1 xref: UniProtKB:Q6IFD0 xref: UniProtKB:Q8NGL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014882 ! OR5L1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029024 name: OR5B2_HUMAN def: "Olfactory receptor 5B2" [UniProtKB:Q96R09] synonym: "Olfactory receptor OR11-240" EXACT [UniProtKB:Q96R09] synonym: "OST073" EXACT [UniProtKB:Q96R09] xref: EMBL:AAK95121.1 xref: EMBL:BAC06070.1 xref: EMBL:DAA04903.1 xref: UniProtKB:Q6IEV7 xref: UniProtKB:Q8NGF5 xref: UniProtKB:Q96R09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014878 ! OR5B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029025 name: OR8U1_HUMAN def: "Olfactory receptor 8U1" [UniProtKB:Q8NH10] xref: EMBL:BAC05831.1 xref: UniProtKB:Q8NH10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014897 ! OR8U1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029027 name: A8MUX1_HUMAN def: "Putative uncharacterized protein OR9G4" [UniProtKB:A8MUX1] xref: UniProtKB:A8MUX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014900 ! OR9G4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029028 name: OR5BC_HUMAN def: "Olfactory receptor 5B12" [UniProtKB:Q96R08] synonym: "Olfactory receptor OR11-241" EXACT [UniProtKB:Q96R08] xref: EMBL:AAK95122.1 xref: EMBL:BAC06069.1 xref: EMBL:DAA04905.1 xref: UniProtKB:Q6IEV5 xref: UniProtKB:Q96R08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014880 ! OR5B12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029029 name: OR5R1_HUMAN def: "Olfactory receptor 5R1" [UniProtKB:Q8NH85] synonym: "Olfactory receptor OR11-185" EXACT [UniProtKB:Q8NH85] xref: EMBL:BAC05752.1 xref: EMBL:DAA04912.1 xref: UniProtKB:Q8NH85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014885 ! OR5R1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029030 name: OR5C1_HUMAN def: "Olfactory receptor 5C1" [UniProtKB:Q8NGR4] synonym: "Olfactory receptor 9-F" EXACT [UniProtKB:Q8NGR4] synonym: "OR9-F" EXACT [UniProtKB:Q8NGR4] xref: EMBL:AAK94999.1 xref: EMBL:BAC05946.1 xref: UniProtKB:Q8NGR4 xref: UniProtKB:Q96RC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019180 ! OR5C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029031 name: OR8G5_HUMAN def: "Olfactory receptor 8G5" [UniProtKB:Q8NG78] synonym: "Olfactory receptor OR11-298" EXACT [UniProtKB:Q8NG78] xref: EMBL:BAC06171.1 xref: EMBL:DAA04914.1 xref: UniProtKB:Q6IEU6 xref: UniProtKB:Q8NG78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014892 ! OR8G5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029032 name: Q6IEU2_HUMAN xref: UniProtKB:Q6IEU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029033 name: OR5J2_HUMAN def: "Olfactory receptor 5J2" [UniProtKB:Q8NH18] synonym: "Olfactory receptor OR11-266" EXACT [UniProtKB:Q8NH18] xref: EMBL:BAC05823.1 xref: EMBL:DAA04915.1 xref: UniProtKB:Q6IEU5 xref: UniProtKB:Q8NH18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007925 ! OR5J2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029034 name: OR8D4_HUMAN def: "Olfactory receptor 8D4" [UniProtKB:Q8NGM9] xref: EMBL:BAC05981.1 xref: UniProtKB:Q8NGM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014889 ! OR8D4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029035 name: O5AR1_HUMAN def: "Olfactory receptor 5AR1" [UniProtKB:Q8NGP9] synonym: "Olfactory receptor OR11-209" EXACT [UniProtKB:Q8NGP9] xref: EMBL:BAC05961.1 xref: EMBL:DAA04799.1 xref: UniProtKB:Q6IF61 xref: UniProtKB:Q8NGP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014866 ! OR5AR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029036 name: Q6IFM9_HUMAN def: "Olfactory receptor OR9-31 (Olfactory receptor, family 5, subfamily C, member 1)" [UniProtKB:Q6IFM9] xref: EMBL:DAA04631.1 xref: EMBL:EAW87544.1 xref: UniProtKB:Q6IFM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019180 ! OR5C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029037 name: A8MXK6_HUMAN def: "Putative uncharacterized protein OR8K5" [UniProtKB:A8MXK6] xref: UniProtKB:A8MXK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014896 ! OR8K5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029038 name: O5AS1_HUMAN def: "Olfactory receptor 5AS1" [UniProtKB:Q8N127] synonym: "Olfactory receptor OR11-168" EXACT [UniProtKB:Q8N127] xref: EMBL:BAC05714.1 xref: EMBL:BAC05788.1 xref: EMBL:DAA04742.1 xref: UniProtKB:Q6IFB8 xref: UniProtKB:Q8N127 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014867 ! OR5AS1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029039 name: OR5BH_HUMAN def: "Olfactory receptor 5B17" [UniProtKB:Q8NGF7] synonym: "Olfactory receptor OR11-237" EXACT [UniProtKB:Q8NGF7] xref: EMBL:BAC06067.1 xref: EMBL:DAA04889.1 xref: UniProtKB:Q6IEX1 xref: UniProtKB:Q8NGF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014881 ! OR5B17_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029040 name: OR5L2_HUMAN def: "Olfactory receptor 5L2" [UniProtKB:Q8NGL0] synonym: "HTPCRX16" EXACT [UniProtKB:Q8NGL0] synonym: "Olfactory receptor OR11-153" EXACT [UniProtKB:Q8NGL0] xref: EMBL:AAK95011.1 xref: EMBL:BAC06002.1 xref: EMBL:DAA04794.1 xref: UniProtKB:Q6IF66 xref: UniProtKB:Q8NGL0 xref: UniProtKB:Q96RB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014883 ! OR5L2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0029042 name: ARHGF_HUMAN def: "Rho guanine nucleotide exchange factor 15" [UniProtKB:O94989] synonym: "Vsm-RhoGEF" EXACT [UniProtKB:O94989] xref: EMBL:AAH36749.1 xref: EMBL:BAA74938.2 xref: EMBL:BAB14703.1 xref: UniProtKB:O94989 xref: UniProtKB:Q8N449 xref: UniProtKB:Q9H8B4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007263 ! ARHGEF15_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0014975 ! arhgef15-prei3 physical interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0029064 name: Q17RW0_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:Q17RW0] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q17RW0] xref: EMBL:AAI17173.1 xref: UniProtKB:Q17RW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004900 ! INSR_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0029069 name: INSRR_HUMAN def: "Insulin receptor-related protein precursor" [UniProtKB:P14616] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P14616] synonym: "IR-related receptor" EXACT [UniProtKB:P14616] synonym: "IRR" EXACT [UniProtKB:P14616] xref: EMBL:AAC17167.1 xref: EMBL:AAC31759.1 xref: EMBL:CAH70009.1 xref: EMBL:EAW52903.1 xref: UniProtKB:O60724 xref: UniProtKB:P14616 xref: UniProtKB:Q5VZS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018294 ! INSRR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0067120 ! INSRR_HUMAN-Phosphotyrosine1145 [Term] id: CCO:B0029082 name: ROS_HUMAN def: "Proto-oncogene tyrosine-protein kinase ROS precursor" [UniProtKB:P08922] synonym: "c-ros-1" EXACT [UniProtKB:P08922] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P08922] xref: EMBL:AAA36580.1 xref: EMBL:AAA60277.1 xref: EMBL:AAA60278.1 xref: EMBL:CAI23378.1 xref: EMBL:CAI42374.1 xref: UniProtKB:P08922 xref: UniProtKB:Q15368 xref: UniProtKB:Q5TDB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014985 ! ROS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0052705 ! ROS_HUMAN-Phosphotyrosine2114 [Term] id: CCO:B0029119 name: Q9UL32_HUMAN def: "Bcl-2 related ovarian killer" [UniProtKB:Q9UL32] xref: EMBL:AAF09129.1 xref: UniProtKB:Q9UL32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007304 ! BOK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0029122 name: BOK_HUMAN def: "Bcl-2-related ovarian killer protein" [UniProtKB:Q9UMX3] synonym: "Hbok" EXACT [UniProtKB:Q9UMX3] xref: EMBL:AAD51719.1 xref: EMBL:AAH06203.1 xref: EMBL:AAP35936.1 xref: UniProtKB:Q9UMX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007304 ! BOK_human relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0029125 name: Q2M5E1_HUMAN def: "Citron" [UniProtKB:Q2M5E1] xref: EMBL:AAV87216.1 xref: UniProtKB:Q2M5E1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0029133 name: PFD2_HUMAN def: "Prefoldin subunit 2" [UniProtKB:Q9UHV9] xref: EMBL:AAD47084.1 xref: EMBL:AAF17218.1 xref: EMBL:AAF36151.1 xref: EMBL:AAH12464.1 xref: EMBL:AAH47042.1 xref: UniProtKB:Q9P0P7 xref: UniProtKB:Q9UHV9 xref: UniProtKB:Q9UN05 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022505 ! PFDN2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0017241 ! map3k3-pfdn2 physical interaction [Term] id: CCO:B0029136 name: A8MZB4_HUMAN def: "Putative uncharacterized protein PPP2R2D (Protein phosphatase 2, regulatory subunit B, delta isoform, isoform CRA_b)" [UniProtKB:A8MZB4] xref: EMBL:EAW49146.1 xref: UniProtKB:A8MZB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007188 ! PPP2R2D_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029137 name: A8MU22_HUMAN def: "Putative uncharacterized protein PPP2R2B (Protein phosphatase 2 (Formerly 2A), regulatory subunit B (PR 52), beta isoform, isoform CRA_d)" [UniProtKB:A8MU22] xref: EMBL:EAW61833.1 xref: UniProtKB:A8MU22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007187 ! PPP2R2B_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029138 name: A8KAK0_HUMAN def: "cDNA FLJ77397, highly similar to Homo sapiens protein phosphatase 2, regulatory subunit B, delta isoform (PPP2R2D), transcript variant 1, mRNA" [UniProtKB:A8KAK0] xref: EMBL:BAF85754.1 xref: UniProtKB:A8KAK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029139 name: A8MSY7_HUMAN def: "cDNA FLJ35796 fis, clone TESTI2005835, highly similar to Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform" [UniProtKB:A8MSY7] synonym: "Protein phosphatase 2 (Formerly 2A), regulatory subunit B (PR 52), gamma isoform, isoform CRA_c" EXACT [UniProtKB:A8MSY7] synonym: "Putative uncharacterized protein PPP2R2C" EXACT [UniProtKB:A8MSY7] xref: EMBL:BAG52658.1 xref: EMBL:EAW82395.1 xref: UniProtKB:A8MSY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007189 ! PPP2R2C_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029141 name: A8MW32_HUMAN def: "Putative uncharacterized protein PPP2R2B" [UniProtKB:A8MW32] xref: UniProtKB:A8MW32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007187 ! PPP2R2B_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029151 name: AMPM1_HUMAN def: "Methionine aminopeptidase 1" [UniProtKB:P53582] synonym: "EC 3.4.11.18" EXACT [UniProtKB:P53582] synonym: "MAP 1" EXACT [UniProtKB:P53582] synonym: "MetAP 1" EXACT [UniProtKB:P53582] synonym: "Peptidase M 1" EXACT [UniProtKB:P53582] xref: EMBL:AAH30054.1 xref: EMBL:BAA07679.1 xref: UniProtKB:P53582 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007235 ! METAP1_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0000687 ! methionyl aminopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001785 ! metalloexopeptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008025 ! cobalt ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0034535 ! AMPM1_HUMAN-Phosphotyrosine253 [Term] id: CCO:B0029172 name: TSAP1_HUMAN def: "tRNA selenocysteine-associated protein 1" [UniProtKB:Q9NX07] synonym: "SECp43" EXACT [UniProtKB:Q9NX07] xref: EMBL:AAH00680.1 xref: EMBL:AAH39879.1 xref: EMBL:BAA91217.1 xref: EMBL:CAI22288.1 xref: EMBL:EAX07689.1 xref: UniProtKB:Q86SU7 xref: UniProtKB:Q9NX07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020368 ! TRSPAP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000465 ! selenocysteine incorporation [Term] id: CCO:B0029277 name: MKLN1_HUMAN def: "Muskelin" [UniProtKB:Q9UL63] xref: EMBL:AAF06698.1 xref: EMBL:AAH02834.2 xref: EMBL:AAH67825.1 xref: EMBL:BAA92042.1 xref: EMBL:CAB82407.1 xref: EMBL:EAL24081.1 xref: EMBL:EAW83782.1 xref: UniProtKB:A4D1M8 xref: UniProtKB:A6NG43 xref: UniProtKB:Q9NSK4 xref: UniProtKB:Q9NUS8 xref: UniProtKB:Q9UL63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007826 ! MKLN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029281 name: Q96FA9_HUMAN def: "ZSCAN20 protein" [UniProtKB:Q96FA9] synonym: "Zinc finger protein 31 (KOX 29), isoform CRA_a" EXACT [UniProtKB:Q96FA9] xref: EMBL:AAH11404.1 xref: EMBL:EAX07454.1 xref: UniProtKB:Q96FA9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0021002 ! ZSCAN20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015209 ! q96fa9-scand1 physical interaction [Term] id: CCO:B0029283 name: ZSC20_HUMAN def: "Zinc finger and SCAN domain-containing protein 20" [UniProtKB:P17040] synonym: "Zinc finger protein 31" EXACT [UniProtKB:P17040] synonym: "Zinc finger protein 360" EXACT [UniProtKB:P17040] synonym: "Zinc finger protein KOX29" EXACT [UniProtKB:P17040] xref: EMBL:AAH08827.1 xref: EMBL:CAA36586.1 xref: UniProtKB:P17040 xref: UniProtKB:Q96H84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021002 ! ZSCAN20_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0029287 name: A6NJN6_HUMAN def: "Putative uncharacterized protein ZSCAN20" [UniProtKB:A6NJN6] xref: UniProtKB:A6NJN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021002 ! ZSCAN20_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0029351 name: EGLN1_HUMAN def: "Egl nine homolog 1" [UniProtKB:Q9GZT9] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q9GZT9] synonym: "HIF-PH2" EXACT [UniProtKB:Q9GZT9] synonym: "HIF-prolyl hydroxylase 2" EXACT [UniProtKB:Q9GZT9] synonym: "HPH-2" EXACT [UniProtKB:Q9GZT9] synonym: "Hypoxia-inducible factor prolyl hydroxylase 2" EXACT [UniProtKB:Q9GZT9] synonym: "PHD2" EXACT [UniProtKB:Q9GZT9] synonym: "Prolyl hydroxylase domain-containing protein 2" EXACT [UniProtKB:Q9GZT9] synonym: "SM-20" EXACT [UniProtKB:Q9GZT9] xref: EMBL:AAG33965.1 xref: EMBL:AAG34568.1 xref: EMBL:AAK07534.1 xref: EMBL:AAK07536.1 xref: EMBL:CAC42509.1 xref: EMBL:CAD38741.2 xref: EMBL:CAH72105.1 xref: EMBL:CAI23092.1 xref: UniProtKB:Q8N3M8 xref: UniProtKB:Q9BZS8 xref: UniProtKB:Q9BZT0 xref: UniProtKB:Q9GZT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007481 ! EGLN1_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0004682 ! peptidyl-proline dioxygenase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0017966 ! os9-egln1 physical interaction relationship: participates_in CCO:I0017967 ! os9-egln1-1 physical interaction relationship: participates_in CCO:I0017969 ! os9-egln1-2 physical interaction relationship: participates_in CCO:I0017970 ! os9-egln1-3 physical interaction relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity [Term] id: CCO:B0029357 name: EGLN2_HUMAN def: "Egl nine homolog 2" [UniProtKB:Q96KS0] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q96KS0] synonym: "Estrogen-induced tag 6" EXACT [UniProtKB:Q96KS0] synonym: "HIF-PH1" EXACT [UniProtKB:Q96KS0] synonym: "HIF-prolyl hydroxylase 1" EXACT [UniProtKB:Q96KS0] synonym: "HPH-3" EXACT [UniProtKB:Q96KS0] synonym: "Hypoxia-inducible factor prolyl hydroxylase 1" EXACT [UniProtKB:Q96KS0] synonym: "PHD1" EXACT [UniProtKB:Q96KS0] synonym: "Prolyl hydroxylase domain-containing protein 1" EXACT [UniProtKB:Q96KS0] xref: EMBL:AAH01723.1 xref: EMBL:AAH36051.1 xref: EMBL:AAK82943.1 xref: EMBL:CAC42510.1 xref: UniProtKB:Q8WWY4 xref: UniProtKB:Q96KS0 xref: UniProtKB:Q9BV14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007482 ! EGLN2_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001777 ! ferrous iron binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors relationship: has_function CCO:F0004184 ! oxygen sensor activity relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020633 ! prei3-egln2 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway [Term] id: CCO:B0029358 name: EGLN3_HUMAN def: "Egl nine homolog 3" [UniProtKB:Q9H6Z9] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q9H6Z9] synonym: "HIF-PH3" EXACT [UniProtKB:Q9H6Z9] synonym: "HIF-prolyl hydroxylase 3" EXACT [UniProtKB:Q9H6Z9] synonym: "HPH-1" EXACT [UniProtKB:Q9H6Z9] synonym: "Hypoxia-inducible factor prolyl hydroxylase 3" EXACT [UniProtKB:Q9H6Z9] synonym: "PHD3" EXACT [UniProtKB:Q9H6Z9] synonym: "Prolyl hydroxylase domain-containing protein 3" EXACT [UniProtKB:Q9H6Z9] xref: EMBL:AAH10992.3 xref: EMBL:AAH64924.2 xref: EMBL:AAI05940.1 xref: EMBL:AAI11058.2 xref: EMBL:BAB15101.1 xref: EMBL:CAC42511.1 xref: UniProtKB:Q2TA79 xref: UniProtKB:Q3B8N4 xref: UniProtKB:Q6P1R2 xref: UniProtKB:Q9H6Z9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007483 ! EGLN3_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018266 ! os9-egln3-1 physical interaction [Term] id: CCO:B0029424 name: BTK_HUMAN def: "Tyrosine-protein kinase BTK" [UniProtKB:Q06187] synonym: "Agammaglobulinaemia tyrosine kinase" EXACT [UniProtKB:Q06187] synonym: "ATK" EXACT [UniProtKB:Q06187] synonym: "B-cell progenitor kinase" EXACT [UniProtKB:Q06187] synonym: "BPK" EXACT [UniProtKB:Q06187] synonym: "Bruton tyrosine kinase" EXACT [UniProtKB:Q06187] synonym: "EC 2.7.10.2" EXACT [UniProtKB:Q06187] xref: EMBL:AAA61479.1 xref: EMBL:AAB60639.1 xref: EMBL:AAB64205.1 xref: EMBL:AAC51347.1 xref: EMBL:AAI09080.1 xref: EMBL:AAI09081.1 xref: EMBL:CAA41728.1 xref: EMBL:CAB55876.1 xref: UniProtKB:Q06187 xref: UniProtKB:Q32ML5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017190 ! BTK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015945 ! btk-gtf21-2 physical interaction relationship: participates_in CCO:I0015946 ! btk-gtf21-3 physical interaction relationship: participates_in CCO:I0016125 ! btk-prkcq-2 physical interaction relationship: participates_in CCO:I0018064 ! btk-gtf21-6 physical interaction relationship: participates_in CCO:I0018195 ! btk-sh3bp5-4 physical interaction relationship: participates_in CCO:I0018196 ! btk-gtf21-5 phosphorylation relationship: participates_in CCO:I0018318 ! btk-sh3bp5-2 physical interaction relationship: participates_in CCO:I0018319 ! btk-sh3bp5-3 physical interaction relationship: participates_in CCO:I0018837 ! gpiv-fcer1g-1 physical interaction relationship: participates_in CCO:I0018838 ! btk-prkcq-1 physical interaction relationship: participates_in CCO:I0019256 ! btk-sh3bp5-1 physical interaction relationship: participates_in CCO:I0019257 ! btk-gtf21-4 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: transforms_into CCO:B0064012 ! BTK_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064013 ! BTK_HUMAN-Phosphotyrosine40 relationship: transforms_into CCO:B0064014 ! BTK_HUMAN-Phosphotyrosine223 relationship: transforms_into CCO:B0064015 ! BTK_HUMAN-Phosphotyrosine344 relationship: transforms_into CCO:B0064016 ! BTK_HUMAN-Phosphotyrosine551 [Term] id: CCO:B0029425 name: Q5JY90_HUMAN def: "cDNA FLJ32543 fis, clone SMINT2000538, highly similar to Tyrosine-protein kinase BTK (EC 2.7.10.2)" [UniProtKB:Q5JY90] synonym: "Bruton agammaglobulinemia tyrosine kinase" EXACT [UniProtKB:Q5JY90] synonym: "Bruton agammaglobulinemia tyrosine kinase, isoform CRA_b" EXACT [UniProtKB:Q5JY90] xref: EMBL:BAG51864.1 xref: EMBL:CAI42359.1 xref: EMBL:EAX02857.1 xref: UniProtKB:Q5JY90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017190 ! BTK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0029451 name: Z3H7B_HUMAN def: "Zinc finger CCCH domain-containing protein 7B" [UniProtKB:Q9UGR2] synonym: "Rotavirus 'X'-associated non-structural protein" EXACT [UniProtKB:Q9UGR2] synonym: "RoXaN" EXACT [UniProtKB:Q9UGR2] xref: EMBL:AAF05541.1 xref: EMBL:AAH24313.2 xref: EMBL:BAA82983.1 xref: EMBL:BAB14701.1 xref: EMBL:CAI23515.1 xref: UniProtKB:Q5TFX9 xref: UniProtKB:Q8TBT9 xref: UniProtKB:Q9H8B6 xref: UniProtKB:Q9UGQ9 xref: UniProtKB:Q9UGR0 xref: UniProtKB:Q9UGR1 xref: UniProtKB:Q9UGR2 xref: UniProtKB:Q9UK03 xref: UniProtKB:Q9UPW9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022793 ! ZC3H7B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019081 ! atxn1-zc3h7b physical interaction relationship: transforms_into CCO:B0071940 ! Z3H7B_HUMAN-Phosphotyrosine664 [Term] id: CCO:B0029479 name: LMO4_HUMAN def: "LIM domain transcription factor LMO4" [UniProtKB:P61968] synonym: "Breast tumor autoantigen" EXACT [UniProtKB:P61968] synonym: "LIM domain only protein 4" EXACT [UniProtKB:P61968] synonym: "LMO-4" EXACT [UniProtKB:P61968] xref: EMBL:AAB51073.1 xref: EMBL:AAH03600.1 xref: EMBL:AAH17673.1 xref: EMBL:AAH65818.1 xref: UniProtKB:O00158 xref: UniProtKB:O88894 xref: UniProtKB:P61968 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018510 ! LMO4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0029480 name: Q8NHM1_HUMAN xref: UniProtKB:Q8NHM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0029482 name: LHX3_HUMAN def: "LIM/homeobox protein Lhx3" [UniProtKB:Q9UBR4] synonym: "LIM homeobox protein 3" EXACT [UniProtKB:Q9UBR4] xref: EMBL:AAF17291.1 xref: EMBL:AAF17292.1 xref: EMBL:AAF26412.1 xref: EMBL:AAF36808.1 xref: EMBL:AAF36809.1 xref: EMBL:AAL26314.1 xref: UniProtKB:Q9NZB5 xref: UniProtKB:Q9P0I8 xref: UniProtKB:Q9P0I9 xref: UniProtKB:Q9UBR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018487 ! LHX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0029488 name: Q9HBU2_HUMAN def: "Lim-homeobox transcription factor LHX3" [UniProtKB:Q9HBU2] xref: EMBL:AAG10399.1 xref: UniProtKB:Q9HBU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018487 ! LHX3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0029592 name: RL36_HUMAN def: "60S ribosomal protein L36" [UniProtKB:Q9Y3U8] xref: EMBL:AAD27776.1 xref: EMBL:AAH03052.1 xref: EMBL:AAH04971.1 xref: EMBL:AAH91508.1 xref: EMBL:BAB79471.1 xref: EMBL:CAB43374.1 xref: EMBL:CAG38496.1 xref: UniProtKB:Q6FIG1 xref: UniProtKB:Q9UQF6 xref: UniProtKB:Q9Y3U8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022579 ! RPL36_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0029646 name: OVGP1_HUMAN def: "Oviduct-specific glycoprotein precursor" [UniProtKB:Q12889] synonym: "Estrogen-dependent oviduct protein" EXACT [UniProtKB:Q12889] synonym: "Mucin-9" EXACT [UniProtKB:Q12889] synonym: "Oviductal glycoprotein" EXACT [UniProtKB:Q12889] synonym: "Oviductin" EXACT [UniProtKB:Q12889] xref: EMBL:AAA86946.1 xref: EMBL:AAB04126.1 xref: EMBL:AAI26178.1 xref: EMBL:CAC36039.1 xref: UniProtKB:A0AV19 xref: UniProtKB:Q12889 xref: UniProtKB:Q15841 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022487 ! OVGP1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds relationship: has_function CCO:F0000952 ! chitinase activity relationship: has_function CCO:F0005808 ! cation binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020650 ! rasa4-ovgp1 physical interaction [Term] id: CCO:B0029683 name: Q56TK0_HUMAN def: "STAT6B" [UniProtKB:Q56TK0] xref: EMBL:AAU04439.1 xref: UniProtKB:Q56TK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008606 ! STAT6B_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029685 name: STAT6_HUMAN def: "Signal transducer and activator of transcription 6" [UniProtKB:P42226] synonym: "IL-4 Stat" EXACT [UniProtKB:P42226] xref: EMBL:AAA57193.1 xref: EMBL:AAC67525.1 xref: EMBL:AAH75852.1 xref: EMBL:AAL06595.1 xref: EMBL:BAD89432.1 xref: UniProtKB:P42226 xref: UniProtKB:Q5FBW5 xref: UniProtKB:Q71UP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008241 ! STAT6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018131 ! nmi-stat6-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002806 ! positive regulation of isotype switching to IgE isotypes relationship: transforms_into CCO:B0035699 ! STAT6_HUMAN-Phosphotyrosine641 [Term] id: CCO:B0029695 name: CEAM6_HUMAN def: "Carcinoembryonic antigen-related cell adhesion molecule 6 precursor" [UniProtKB:P40199] synonym: "CD66c antigen" EXACT [UniProtKB:P40199] synonym: "Non-specific crossreacting antigen" EXACT [UniProtKB:P40199] synonym: "Normal cross-reacting antigen" EXACT [UniProtKB:P40199] xref: EMBL:AAA59907.1 xref: EMBL:AAA59915.1 xref: EMBL:AAH05008.1 xref: UniProtKB:P40199 xref: UniProtKB:Q14920 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007376 ! CEACAM6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0052321 ! CEAM6_HUMAN-Phosphoserine243 [Term] id: CCO:B0029706 name: Q8N4D0_HUMAN def: "Carcinoembryonic antigen-related cell adhesion molecule 5" [UniProtKB:Q8N4D0] xref: EMBL:AAH34671.1 xref: UniProtKB:Q8N4D0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007375 ! CEACAM5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015475 ! ewsr1-q8n4d0 physical interaction [Term] id: CCO:B0029727 name: CEAM1_HUMAN def: "Carcinoembryonic antigen-related cell adhesion molecule 1 precursor" [UniProtKB:P13688] synonym: "BGP-1" EXACT [UniProtKB:P13688] synonym: "Biliary glycoprotein 1" EXACT [UniProtKB:P13688] synonym: "CD66a antigen" EXACT [UniProtKB:P13688] xref: EMBL:AAA51825.1 xref: EMBL:AAA51826.1 xref: EMBL:AAA57142.1 xref: EMBL:AAA58393.1 xref: EMBL:AAA58394.1 xref: EMBL:AAC18433.1 xref: EMBL:AAC18434.1 xref: EMBL:AAC18435.1 xref: EMBL:AAC18437.1 xref: EMBL:AAC18438.1 xref: EMBL:AAC18439.1 xref: EMBL:BAA14341.1 xref: EMBL:BAA14342.1 xref: EMBL:BAA14343.1 xref: EMBL:CAA32940.1 xref: EMBL:CAA34404.1 xref: EMBL:CAA47694.1 xref: UniProtKB:O60430 xref: UniProtKB:P13688 xref: UniProtKB:Q13858 xref: UniProtKB:Q15600 xref: UniProtKB:Q9UQV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007372 ! CEACAM1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0034641 ! CEAM1_HUMAN-Pyrrolidone carboxylic acid35 [Term] id: CCO:B0029795 name: L1CAM_HUMAN def: "Neural cell adhesion molecule L1 precursor" [UniProtKB:P32004] synonym: "CD171 antigen" EXACT [UniProtKB:P32004] synonym: "N-CAM L1" EXACT [UniProtKB:P32004] xref: EMBL:AAA36353.1 xref: EMBL:AAA59476.1 xref: EMBL:AAC14352.1 xref: EMBL:AAH25843.1 xref: EMBL:AAI26230.1 xref: EMBL:CAA41576.1 xref: EMBL:CAA42508.1 xref: EMBL:CAA82564.1 xref: EMBL:CAB37831.1 xref: UniProtKB:A0AV65 xref: UniProtKB:P32004 xref: UniProtKB:Q8TA87 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007769 ! L1CAM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020356 ! l1cam-pea15 physical interaction relationship: transforms_into CCO:B0035077 ! L1CAM_HUMAN-Phosphoserine1163 relationship: transforms_into CCO:B0035078 ! L1CAM_HUMAN-Phosphoserine1190 relationship: transforms_into CCO:B0035079 ! L1CAM_HUMAN-Phosphoserine1191 relationship: transforms_into CCO:B0035080 ! L1CAM_HUMAN-Phosphoserine1194 relationship: transforms_into CCO:B0035081 ! L1CAM_HUMAN-Phosphothreonine1247 relationship: transforms_into CCO:B0035082 ! L1CAM_HUMAN-Phosphoserine1248 [Term] id: CCO:B0029859 name: Q9BUX6_HUMAN def: "RAP1, GTP-GDP dissociation stimulator 1" [UniProtKB:Q9BUX6] xref: EMBL:AAH01816.1 xref: EMBL:AAH01851.2 xref: EMBL:AAP35483.1 xref: UniProtKB:Q9BUW9 xref: UniProtKB:Q9BUX6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022858 ! RAP1GDS1_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015248 ! mbip-rap1gds1 physical interaction relationship: participates_in CCO:I0015467 ! rap1gds1-znf451 physical interaction [Term] id: CCO:B0029881 name: O15302_HUMAN def: "CaM kinase II isoform" [UniProtKB:O15302] xref: EMBL:AAB66908.1 xref: UniProtKB:O15302 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001826 ! 7S RNA binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0002002 ! signal recognition particle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0029890 name: FA21C_HUMAN def: "Protein FAM21C" [UniProtKB:Q9Y4E1] xref: EMBL:AAH06456.1 xref: EMBL:BAA25518.1 xref: EMBL:CAB43380.2 xref: EMBL:CAI15257.1 xref: EMBL:CAI15258.1 xref: EMBL:CAI16355.1 xref: EMBL:CAI16356.1 xref: UniProtKB:Q5SQU4 xref: UniProtKB:Q5SQU5 xref: UniProtKB:Q7L521 xref: UniProtKB:Q9UG79 xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022243 ! FAM21C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019091 ! atxn1-fam21c physical interaction relationship: transforms_into CCO:B0066074 ! FA21C_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0066075 ! FA21C_HUMAN-Phosphoserine160 relationship: transforms_into CCO:B0066076 ! FA21C_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0066077 ! FA21C_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0066078 ! FA21C_HUMAN-Phosphoserine250 relationship: transforms_into CCO:B0066079 ! FA21C_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0066080 ! FA21C_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0066081 ! FA21C_HUMAN-Phosphothreonine287 relationship: transforms_into CCO:B0066082 ! FA21C_HUMAN-Phosphoserine288 relationship: transforms_into CCO:B0066083 ! FA21C_HUMAN-Phosphothreonine331 relationship: transforms_into CCO:B0066084 ! FA21C_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0066085 ! FA21C_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0066086 ! FA21C_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0066087 ! FA21C_HUMAN-Phosphoserine441 relationship: transforms_into CCO:B0066088 ! FA21C_HUMAN-Phosphoserine498 relationship: transforms_into CCO:B0066089 ! FA21C_HUMAN-Phosphothreonine502 relationship: transforms_into CCO:B0066090 ! FA21C_HUMAN-Phosphoserine504 relationship: transforms_into CCO:B0066091 ! FA21C_HUMAN-Phosphoserine539 relationship: transforms_into CCO:B0066092 ! FA21C_HUMAN-Phosphoserine619 relationship: transforms_into CCO:B0066093 ! FA21C_HUMAN-Phosphoserine620 relationship: transforms_into CCO:B0066094 ! FA21C_HUMAN-Phosphoserine752 relationship: transforms_into CCO:B0066095 ! FA21C_HUMAN-Phosphothreonine797 relationship: transforms_into CCO:B0066096 ! FA21C_HUMAN-Phosphothreonine799 relationship: transforms_into CCO:B0066097 ! FA21C_HUMAN-Phosphoserine802 relationship: transforms_into CCO:B0066098 ! FA21C_HUMAN-Phosphoserine874 relationship: transforms_into CCO:B0066099 ! FA21C_HUMAN-Phosphoserine1033 relationship: transforms_into CCO:B0066100 ! FA21C_HUMAN-Phosphoserine1054 relationship: transforms_into CCO:B0066101 ! FA21C_HUMAN-Phosphoserine1158 relationship: transforms_into CCO:B0066102 ! FA21C_HUMAN-Phosphoserine1159 [Term] id: CCO:B0030003 name: MATN2_HUMAN def: "Matrilin-2 precursor" [UniProtKB:O00339] xref: EMBL:AAC51260.2 xref: EMBL:AAH10444.1 xref: EMBL:AAH16394.1 xref: EMBL:AAQ89254.1 xref: EMBL:CAB70853.2 xref: EMBL:CAD38787.1 xref: UniProtKB:O00339 xref: UniProtKB:Q6UWA5 xref: UniProtKB:Q7Z5X1 xref: UniProtKB:Q8NDE6 xref: UniProtKB:Q96FT5 xref: UniProtKB:Q9NSZ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022389 ! MATN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019098 ! atxn1-matn2 physical interaction relationship: transforms_into CCO:B0068003 ! MATN2_HUMAN-Phosphoserine894 relationship: transforms_into CCO:B0068004 ! MATN2_HUMAN-Phosphothreonine895 [Term] id: CCO:B0030075 name: A8MTR7_HUMAN xref: UniProtKB:A8MTR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0030140 name: Q5C8S5_HUMAN def: "Estrogen receptor alpha mamillary body 1 isoform" [UniProtKB:Q5C8S5] xref: EMBL:AAW69860.1 xref: UniProtKB:Q5C8S5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030141 name: Q0H8T6_HUMAN def: "Hippocampal estrogen receptor alpha isoform TADDI" [UniProtKB:Q0H8T6] xref: EMBL:ABA41493.1 xref: UniProtKB:Q0H8T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004590 ! ESR1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030142 name: Q9UE35_HUMAN def: "Estrogen receptor protein (Estrogen receptor 1)" [UniProtKB:Q9UE35] xref: EMBL:CAA44322.1 xref: EMBL:CAQ07854.1 xref: UniProtKB:Q9UE35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021275 ! estrogen receptor_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030143 name: Q6MZQ9_HUMAN def: "Putative uncharacterized protein DKFZp686N23123" [UniProtKB:Q6MZQ9] xref: EMBL:CAE45969.1 xref: UniProtKB:Q6MZQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021183 ! DKFZp686N23123_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030164 name: TLR1_HUMAN def: "Toll-like receptor 1 precursor" [UniProtKB:Q15399] synonym: "CD281 antigen" EXACT [UniProtKB:Q15399] synonym: "TIL" EXACT [UniProtKB:Q15399] synonym: "Toll/interleukin-1 receptor-like protein" EXACT [UniProtKB:Q15399] xref: EMBL:AAC34137.1 xref: EMBL:AAI09095.1 xref: EMBL:BAA02801.2 xref: EMBL:CAB43364.1 xref: UniProtKB:O15452 xref: UniProtKB:Q15399 xref: UniProtKB:Q32MK3 xref: UniProtKB:Q9UG90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008298 ! TLR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002099 ! positive regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002351 ! positive regulation of interleukin-6 biosynthetic process [Term] id: CCO:B0030165 name: TLR10_HUMAN def: "Toll-like receptor 10 precursor" [UniProtKB:Q9BXR5] synonym: "CD290 antigen" EXACT [UniProtKB:Q9BXR5] xref: EMBL:AAH89406.1 xref: EMBL:AAK26744.1 xref: EMBL:AAQ88667.1 xref: UniProtKB:Q5FWG4 xref: UniProtKB:Q6UXL3 xref: UniProtKB:Q9BXR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008297 ! TLR10_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0030167 name: Q2NKL3_HUMAN def: "TLR6 protein" [UniProtKB:Q2NKL3] xref: EMBL:AAI11756.1 xref: UniProtKB:Q2NKL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008300 ! TLR6_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0030171 name: TLR2_HUMAN def: "Toll-like receptor 2 precursor" [UniProtKB:O60603] synonym: "CD282 antigen" EXACT [UniProtKB:O60603] synonym: "Toll/interleukin-1 receptor-like protein 4" EXACT [UniProtKB:O60603] xref: EMBL:AAC34133.1 xref: EMBL:AAC34377.1 xref: EMBL:AAH33756.1 xref: EMBL:AAM23001.1 xref: UniProtKB:O15454 xref: UniProtKB:O60603 xref: UniProtKB:Q8NI00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008299 ! TLR2_human relationship: has_function CCO:F0000243 ! lipopolysaccharide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001838 ! pattern recognition receptor activity relationship: has_function CCO:F0005721 ! peptidoglycan binding relationship: has_function CCO:F0008054 ! Gram-positive bacterial binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0017933 ! tlr2-myd88 colocalization relationship: participates_in CCO:P0000568 ! cell surface pattern recognition receptor signaling pathway relationship: participates_in CCO:P0000571 ! MyD88-dependent toll-like receptor signaling pathway relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0030172 name: TLR6_HUMAN def: "Toll-like receptor 6 precursor" [UniProtKB:Q9Y2C9] synonym: "CD286 antigen" EXACT [UniProtKB:Q9Y2C9] xref: EMBL:BAA78631.1 xref: UniProtKB:Q9Y2C9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008300 ! TLR6_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002351 ! positive regulation of interleukin-6 biosynthetic process [Term] id: CCO:B0030185 name: A8MS99_HUMAN def: "Putative uncharacterized protein RXRB" [UniProtKB:A8MS99] xref: UniProtKB:A8MS99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008140 ! RXRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030221 name: Q96AW0_HUMAN def: "Dystrobrevin, beta" [UniProtKB:Q96AW0] synonym: "Dystrobrevin, beta, isoform CRA_d" EXACT [UniProtKB:Q96AW0] xref: EMBL:AAH16655.1 xref: EMBL:AAP88807.1 xref: EMBL:EAX00722.1 xref: UniProtKB:Q96AW0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022850 ! DTNB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015022 ! dtnb-nup62 physical interaction relationship: participates_in CCO:I0015245 ! dtnb-traf2 physical interaction relationship: participates_in CCO:I0015750 ! dtnb-hmg20a physical interaction [Term] id: CCO:B0030243 name: Q6NT27_HUMAN def: "Guanine nucleotide binding protein (G protein), q polypeptide" [UniProtKB:Q6NT27] synonym: "Guanine nucleotide binding protein (G protein), q polypeptide, isoform CRA_c" EXACT [UniProtKB:Q6NT27] xref: EMBL:AAH57777.1 xref: EMBL:AAH67850.1 xref: EMBL:AAH69520.1 xref: EMBL:AAH75096.1 xref: EMBL:AAH75097.1 xref: EMBL:CAI12198.1 xref: EMBL:CAI14669.1 xref: EMBL:CAI15999.1 xref: EMBL:EAW62607.1 xref: UniProtKB:Q6NT27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014749 ! GNAQ_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0030246 name: Q6LCB5_HUMAN def: "WUGSC:H_LUCA15.1 protein" [UniProtKB:Q6LCB5] xref: EMBL:AAD12230.1 xref: UniProtKB:Q6LCB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015205 ! WUGSC:H_LUCA15.1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0030249 name: GNAZ_HUMAN def: "Guanine nucleotide-binding protein G(z) subunit alpha" [UniProtKB:P19086] synonym: "G(x) alpha chain" EXACT [UniProtKB:P19086] synonym: "Gz-alpha" EXACT [UniProtKB:P19086] xref: EMBL:AAA52580.1 xref: EMBL:AAH78163.1 xref: EMBL:AAH96828.1 xref: EMBL:AAM12613.1 xref: EMBL:BAA14180.1 xref: EMBL:CAG30381.1 xref: UniProtKB:P19086 xref: UniProtKB:Q4QRJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014753 ! GNAZ_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0052418 ! GNAZ_HUMAN-ADP-ribosylarginine179 [Term] id: CCO:B0030251 name: GNA11_HUMAN def: "Guanine nucleotide-binding protein subunit alpha-11" [UniProtKB:P29992] synonym: "G alpha-11" EXACT [UniProtKB:P29992] synonym: "G-protein subunit alpha-11" EXACT [UniProtKB:P29992] synonym: "Guanine nucleotide-binding protein G(y) subunit alpha" EXACT [UniProtKB:P29992] xref: EMBL:AAA58624.1 xref: EMBL:AAA99949.1 xref: EMBL:AAB64303.1 xref: EMBL:AAC25615.1 xref: EMBL:AAH89041.1 xref: EMBL:AAH96225.1 xref: EMBL:AAH96226.1 xref: EMBL:AAH96227.1 xref: EMBL:AAM12614.1 xref: EMBL:CAG33285.1 xref: UniProtKB:O15109 xref: UniProtKB:P29992 xref: UniProtKB:Q14350 xref: UniProtKB:Q6IB00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014745 ! GNA11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0002448 ! regulation of melanocyte differentiation relationship: participates_in CCO:P0003263 ! dopamine receptor, phospholipase C activating pathway relationship: transforms_into CCO:B0052406 ! GNA11_HUMAN-ADP-ribosylarginine183 [Term] id: CCO:B0030261 name: GNA14_HUMAN def: "Guanine nucleotide-binding protein subunit alpha-14" [UniProtKB:O95837] synonym: "G alpha-14" EXACT [UniProtKB:O95837] synonym: "G-protein subunit alpha-14" EXACT [UniProtKB:O95837] xref: EMBL:AAD17944.1 xref: EMBL:AAH27886.1 xref: EMBL:AAM12617.1 xref: UniProtKB:O95837 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014746 ! GNA14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0052407 ! GNA14_HUMAN-ADP-ribosylarginine179 [Term] id: CCO:B0030262 name: GNAT2_HUMAN def: "Guanine nucleotide-binding protein G(t) subunit alpha-2" [UniProtKB:P19087] synonym: "Transducin alpha-2 chain" EXACT [UniProtKB:P19087] xref: EMBL:AAH00233.1 xref: EMBL:AAM12623.1 xref: EMBL:BAA01211.1 xref: EMBL:CAA79310.1 xref: UniProtKB:P19087 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014751 ! GNAT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0052416 ! GNAT2_HUMAN-ADP-ribosylarginine178 relationship: transforms_into CCO:B0052417 ! GNAT2_HUMAN-ADP-ribosylcysteine351 [Term] id: CCO:B0030265 name: Q6B6N3_HUMAN def: "Galphai2 protein" [UniProtKB:Q6B6N3] xref: EMBL:AAT78421.1 xref: UniProtKB:Q6B6N3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0030266 name: GNAT1_HUMAN def: "Guanine nucleotide-binding protein G(t) subunit alpha-1" [UniProtKB:P11488] synonym: "Transducin alpha-1 chain" EXACT [UniProtKB:P11488] xref: EMBL:AAB54048.1 xref: EMBL:AAH95505.1 xref: EMBL:AAM12622.1 xref: EMBL:CAA33196.1 xref: EMBL:CAB37839.2 xref: UniProtKB:P11488 xref: UniProtKB:Q4VBN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014750 ! GNAT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0052413 ! GNAT1_HUMAN-Phosphotyrosine142 relationship: transforms_into CCO:B0052414 ! GNAT1_HUMAN-ADP-ribosylarginine174 relationship: transforms_into CCO:B0052415 ! GNAT1_HUMAN-ADP-ribosylcysteine347 [Term] id: CCO:B0030269 name: GNAI3_HUMAN def: "Guanine nucleotide-binding protein G(k) subunit alpha" [UniProtKB:P08754] synonym: "G(i) alpha-3" EXACT [UniProtKB:P08754] xref: EMBL:AAA35895.1 xref: EMBL:AAA35896.1 xref: EMBL:AAA35939.1 xref: EMBL:AAA52557.1 xref: EMBL:AAA52579.1 xref: EMBL:AAH25285.1 xref: EMBL:AAM12621.1 xref: EMBL:AAV38777.1 xref: UniProtKB:P08754 xref: UniProtKB:P17539 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014747 ! GNAI3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0016767 ! map3k3-gnai3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0052408 ! GNAI3_HUMAN-ADP-ribosylarginine178 relationship: transforms_into CCO:B0052409 ! GNAI3_HUMAN-ADP-ribosylcysteine351 relationship: transforms_into CCO:B0066486 ! GNAI3_HUMAN-Phosphotyrosine69 [Term] id: CCO:B0030277 name: RND3_HUMAN def: "Rho-related GTP-binding protein RhoE precursor" [UniProtKB:P61587] synonym: "MemB protein" EXACT [UniProtKB:P61587] synonym: "Rho family GTPase 3" EXACT [UniProtKB:P61587] synonym: "Rho8" EXACT [UniProtKB:P61587] synonym: "Rnd3" EXACT [UniProtKB:P61587] xref: EMBL:AAB47133.1 xref: EMBL:AAH12513.1 xref: EMBL:AAM21116.1 xref: EMBL:AAP35415.1 xref: EMBL:CAA64603.1 xref: EMBL:CAA66352.1 xref: UniProtKB:P52199 xref: UniProtKB:P61587 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008116 ! RND3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017824 ! plxnb1-rnd3-1 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035594 ! RND3_HUMAN-Cysteine methyl ester241 [Term] id: CCO:B0030278 name: RND1_HUMAN def: "Rho-related GTP-binding protein Rho6 precursor" [UniProtKB:Q92730] synonym: "Rho family GTPase 1" EXACT [UniProtKB:Q92730] synonym: "Rnd1" EXACT [UniProtKB:Q92730] xref: EMBL:AAH26356.1 xref: EMBL:AAM21114.1 xref: EMBL:BAB17851.1 xref: EMBL:CAA69228.1 xref: UniProtKB:Q92730 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008114 ! RND1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000464 ! adherens junction relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0017823 ! plxnb1-rnd1-1 physical interaction relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035592 ! RND1_HUMAN-Cysteine methyl ester229 [Term] id: CCO:B0030280 name: RND2_HUMAN def: "Rho-related GTP-binding protein RhoN precursor" [UniProtKB:P52198] synonym: "Rho family GTPase 2" EXACT [UniProtKB:P52198] synonym: "Rho7" EXACT [UniProtKB:P52198] synonym: "Rnd2" EXACT [UniProtKB:P52198] xref: EMBL:AAC37595.1 xref: EMBL:AAH94842.1 xref: EMBL:AAI04987.1 xref: EMBL:AAI04991.1 xref: EMBL:AAM21115.1 xref: EMBL:AAV38201.1 xref: EMBL:CAA64726.1 xref: UniProtKB:O00690 xref: UniProtKB:O00734 xref: UniProtKB:P52198 xref: UniProtKB:Q5U0P6 xref: UniProtKB:Q99535 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008115 ! RND2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035593 ! RND2_HUMAN-Cysteine methyl ester224 [Term] id: CCO:B0030301 name: PRPS1_HUMAN def: "Ribose-phosphate pyrophosphokinase 1" [UniProtKB:P60891] synonym: "EC 2.7.6.1" EXACT [UniProtKB:P60891] synonym: "Phosphoribosyl pyrophosphate synthetase I" EXACT [UniProtKB:P60891] synonym: "PPRibP" EXACT [UniProtKB:P60891] synonym: "PRS-I" EXACT [UniProtKB:P60891] xref: EMBL:AAH01605.1 xref: EMBL:BAA00733.1 xref: EMBL:CAA33386.1 xref: EMBL:CAI41098.1 xref: EMBL:CAI42173.1 xref: EMBL:EAX02709.1 xref: UniProtKB:B1ALA8 xref: UniProtKB:P09329 xref: UniProtKB:P60891 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022533 ! PRPS1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001114 ! ribose phosphate diphosphokinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015474 ! prps1-spg21 physical interaction [Term] id: CCO:B0030312 name: ETV3_HUMAN def: "ETS translocation variant 3" [UniProtKB:P41162] synonym: "ETS domain transcriptional repressor PE1" EXACT [UniProtKB:P41162] synonym: "Mitogenic Ets transcriptional suppressor" EXACT [UniProtKB:P41162] synonym: "PE-1" EXACT [UniProtKB:P41162] xref: EMBL:AAA60949.1 xref: EMBL:AAH22868.1 xref: EMBL:AAK56846.1 xref: EMBL:CAC36082.1 xref: EMBL:CAH70131.1 xref: UniProtKB:P41162 xref: UniProtKB:Q8TAC8 xref: UniProtKB:Q9BX30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017739 ! ETV3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030313 name: ETS1_HUMAN def: "Protein C-ets-1" [UniProtKB:P14921] synonym: "p54" EXACT [UniProtKB:P14921] xref: EMBL:AAA52409.1 xref: EMBL:AAA52410.1 xref: EMBL:AAB28747.1 xref: EMBL:AAV38259.1 xref: EMBL:CAA32903.1 xref: EMBL:CAA32904.1 xref: UniProtKB:P14921 xref: UniProtKB:Q14278 xref: UniProtKB:Q16080 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017734 ! ETS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002462 ! positive regulation of erythrocyte differentiation relationship: transforms_into CCO:B0065166 ! ETS1_HUMAN-Phosphothreonine38 relationship: transforms_into CCO:B0065167 ! ETS1_HUMAN-Phosphotyrosine205 relationship: transforms_into CCO:B0065168 ! ETS1_HUMAN-Phosphotyrosine223 [Term] id: CCO:B0030315 name: ETV2_HUMAN def: "ETS translocation variant 2" [UniProtKB:O00321] synonym: "Ets-related protein 71" EXACT [UniProtKB:O00321] xref: EMBL:AAB57630.1 xref: EMBL:AAD00861.1 xref: UniProtKB:O00321 xref: UniProtKB:Q9UEA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017737 ! ETV2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030316 name: ETS2_HUMAN def: "Protein C-ets-2" [UniProtKB:P15036] xref: EMBL:AAA52411.1 xref: EMBL:AAA52412.1 xref: EMBL:AAB94057.1 xref: EMBL:AAH17040.1 xref: EMBL:AAH42954.1 xref: EMBL:AAP35484.1 xref: EMBL:BAA95514.1 xref: EMBL:BAG37939.1 xref: EMBL:CAA38966.1 xref: EMBL:CAB90468.1 xref: EMBL:EAX09673.1 xref: UniProtKB:A6NM68 xref: UniProtKB:P15036 xref: UniProtKB:Q53Y89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017735 ! ETS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030317 name: Q6N087_HUMAN def: "Putative uncharacterized protein DKFZp686D0662" [UniProtKB:Q6N087] xref: EMBL:CAE45783.1 xref: UniProtKB:Q6N087 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021188 ! DKFZp686D0662_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030323 name: Q3KNT2_HUMAN def: "ETV2 protein" [UniProtKB:Q3KNT2] xref: EMBL:AAI07125.1 xref: UniProtKB:Q3KNT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017737 ! ETV2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030326 name: A6NFN5_HUMAN def: "Putative uncharacterized protein ETV2" [UniProtKB:A6NFN5] xref: UniProtKB:A6NFN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017737 ! ETV2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0030377 name: DDX56_HUMAN def: "Probable ATP-dependent RNA helicase DDX56" [UniProtKB:Q9NY93] synonym: "ATP-dependent 61 kDa nucleolar RNA helicase" EXACT [UniProtKB:Q9NY93] synonym: "DEAD box protein 56" EXACT [UniProtKB:Q9NY93] synonym: "DEAD-box protein 21" EXACT [UniProtKB:Q9NY93] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9NY93] xref: EMBL:AAG36876.1 xref: EMBL:AAH01235.1 xref: EMBL:BAB14238.1 xref: EMBL:CAB66635.1 xref: EMBL:CAB87992.1 xref: EMBL:CAG33494.1 xref: UniProtKB:Q6IAE2 xref: UniProtKB:Q9H9I8 xref: UniProtKB:Q9NY93 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007451 ! DDX56_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017339 ! znf408-ddx56 physical interaction relationship: transforms_into CCO:B0034696 ! DDX56_HUMAN-Phosphoserine126 [Term] id: CCO:B0030400 name: A8K7M3_HUMAN def: "Septin" [UniProtKB:A8K7M3] xref: EMBL:BAF84727.1 xref: UniProtKB:A8K7M3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0030465 name: RS23_HUMAN def: "40S ribosomal protein S23" [UniProtKB:P62266] xref: EMBL:AAH70221.1 xref: EMBL:BAA03400.1 xref: EMBL:BAA25822.1 xref: EMBL:CAG33277.1 xref: UniProtKB:P39028 xref: UniProtKB:P62266 xref: UniProtKB:Q6IB08 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022611 ! RPS23_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016645 ! map3k1-rps23 physical interaction [Term] id: CCO:B0030504 name: Q5VVI0_HUMAN def: "Neurogenin 3 (cDNA, FLJ94597, highly similar to Homo sapiens neurogenin 3 (NEUROG3), mRNA)" [UniProtKB:Q5VVI0] xref: EMBL:AAI17489.1 xref: EMBL:AAI26469.1 xref: EMBL:BAG36669.1 xref: EMBL:CAH72729.1 xref: EMBL:EAW54328.1 xref: UniProtKB:Q5VVI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007880 ! NEUROG3_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0030506 name: NGN2_HUMAN def: "Neurogenin-2" [UniProtKB:Q9H2A3] synonym: "Protein atonal homolog 4" EXACT [UniProtKB:Q9H2A3] xref: EMBL:AAG40770.1 xref: EMBL:AAH36847.1 xref: UniProtKB:Q8N416 xref: UniProtKB:Q9H2A3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007879 ! NEUROG2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0030509 name: NGN3_HUMAN def: "Neurogenin-3" [UniProtKB:Q9Y4Z2] synonym: "Protein atonal homolog 5" EXACT [UniProtKB:Q9Y4Z2] xref: EMBL:AAK15022.1 xref: EMBL:CAB45384.1 xref: UniProtKB:Q9BY24 xref: UniProtKB:Q9Y4Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007880 ! NEUROG3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0030552 name: MC3R_HUMAN def: "Melanocortin receptor 3" [UniProtKB:P41968] synonym: "MC3-R" EXACT [UniProtKB:P41968] xref: EMBL:AAC13541.1 xref: EMBL:AAH69105.1 xref: EMBL:AAH69599.1 xref: EMBL:AAH96702.1 xref: EMBL:AAH96737.1 xref: EMBL:AAH98169.1 xref: EMBL:AAH98351.1 xref: EMBL:AAO72726.1 xref: EMBL:CAC15480.2 xref: UniProtKB:P41968 xref: UniProtKB:Q4KN27 xref: UniProtKB:Q9H517 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013591 ! MC3R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0030561 name: MSHR_HUMAN def: "Melanocyte-stimulating hormone receptor" [UniProtKB:Q01726] synonym: "MC1-R" EXACT [UniProtKB:Q01726] synonym: "Melanocortin receptor 1" EXACT [UniProtKB:Q01726] synonym: "Melanotropin receptor" EXACT [UniProtKB:Q01726] synonym: "MSH-R" EXACT [UniProtKB:Q01726] xref: EMBL:AAD41349.1 xref: EMBL:AAD41350.1 xref: EMBL:AAD41351.1 xref: EMBL:AAD41352.1 xref: EMBL:AAD41353.1 xref: EMBL:AAD41354.1 xref: EMBL:AAD41355.1 xref: EMBL:AAH07856.1 xref: EMBL:AAK01121.1 xref: EMBL:AAK58525.1 xref: EMBL:AAL05887.1 xref: EMBL:AAL05888.1 xref: EMBL:AAM44861.1 xref: EMBL:AAO67713.1 xref: EMBL:CAA46588.1 xref: EMBL:CAA47865.1 xref: UniProtKB:Q01726 xref: UniProtKB:Q8WWX6 xref: UniProtKB:Q8WWX7 xref: UniProtKB:Q96I33 xref: UniProtKB:Q96RU4 xref: UniProtKB:Q9UBF7 xref: UniProtKB:Q9UN58 xref: UniProtKB:Q9UN59 xref: UniProtKB:Q9UN60 xref: UniProtKB:Q9UN61 xref: UniProtKB:Q9UN62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013599 ! MC1R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_function CCO:F0001318 ! melanocyte stimulating hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0030569 name: MC5R_HUMAN def: "Melanocortin receptor 5" [UniProtKB:P33032] synonym: "MC-2" EXACT [UniProtKB:P33032] synonym: "MC5-R" EXACT [UniProtKB:P33032] xref: EMBL:AAA59566.1 xref: EMBL:AAB60376.1 xref: EMBL:AAH69153.1 xref: EMBL:AAH69545.1 xref: EMBL:AAP23196.1 xref: EMBL:CAA80962.1 xref: UniProtKB:P33032 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013593 ! MC5R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0030574 name: MC4R_HUMAN def: "Melanocortin receptor 4" [UniProtKB:P32245] synonym: "MC4-R" EXACT [UniProtKB:P32245] xref: EMBL:AAA35791.1 xref: EMBL:AAB33341.1 xref: EMBL:AAH69172.1 xref: EMBL:AAI01803.1 xref: EMBL:AAI11993.1 xref: EMBL:AAO92061.1 xref: UniProtKB:P32245 xref: UniProtKB:Q16317 xref: UniProtKB:Q3MIJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013592 ! MC4R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:B0030577 name: ACTHR_HUMAN def: "Adrenocorticotropic hormone receptor" [UniProtKB:Q01718] synonym: "ACTH receptor" EXACT [UniProtKB:Q01718] synonym: "ACTH-R" EXACT [UniProtKB:Q01718] synonym: "Adrenocorticotropin receptor" EXACT [UniProtKB:Q01718] synonym: "MC2-R" EXACT [UniProtKB:Q01718] synonym: "Melanocortin receptor 2" EXACT [UniProtKB:Q01718] xref: EMBL:AAH69074.1 xref: EMBL:AAH94710.1 xref: EMBL:AAI04170.1 xref: EMBL:AAI04171.1 xref: EMBL:AAO67714.1 xref: EMBL:BAC06130.1 xref: EMBL:CAA46587.1 xref: UniProtKB:Q01718 xref: UniProtKB:Q3MI45 xref: UniProtKB:Q504X6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013475 ! MC2R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_function CCO:F0001316 ! adrenocorticotropin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0030604 name: A8K7W5_HUMAN def: "cDNA FLJ77926, highly similar to Homo sapiens protein kinase N1 (PKN1), transcript variant 1, mRNA" [UniProtKB:A8K7W5] xref: EMBL:BAF84819.1 xref: UniProtKB:A8K7W5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0030607 name: Q5VZY9_HUMAN def: "Doublecortin and CaM kinase-like 1" [UniProtKB:Q5VZY9] xref: EMBL:CAH70169.1 xref: EMBL:CAH70263.1 xref: EMBL:CAH70658.1 xref: EMBL:CAI15722.1 xref: UniProtKB:Q5VZY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021149 ! DCAMKL1_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0030613 name: DCLK1_HUMAN def: "Serine/threonine-protein kinase DCLK1" [UniProtKB:O15075] synonym: "Doublecortin-like and CAM kinase-like 1" EXACT [UniProtKB:O15075] synonym: "Doublecortin-like kinase 1" EXACT [UniProtKB:O15075] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O15075] xref: EMBL:AAI52457.1 xref: EMBL:BAA20824.2 xref: EMBL:CAH70167.1 xref: EMBL:CAH70168.1 xref: EMBL:CAH70261.1 xref: EMBL:CAH70262.1 xref: EMBL:CAH70656.1 xref: EMBL:CAH70657.1 xref: EMBL:CAI15720.1 xref: EMBL:CAI15721.1 xref: EMBL:EAX08550.1 xref: EMBL:EAX08551.1 xref: UniProtKB:O15075 xref: UniProtKB:Q5VZZ0 xref: UniProtKB:Q5VZZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017532 ! DCLK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064648 ! DCLK1_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0064649 ! DCLK1_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0064650 ! DCLK1_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0064651 ! DCLK1_HUMAN-Phosphothreonine336 relationship: transforms_into CCO:B0064652 ! DCLK1_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0064653 ! DCLK1_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0064654 ! DCLK1_HUMAN-Phosphotyrosine493 relationship: transforms_into CCO:B0064655 ! DCLK1_HUMAN-Phosphotyrosine520 relationship: transforms_into CCO:B0064656 ! DCLK1_HUMAN-Phosphoserine722 relationship: transforms_into CCO:B0064657 ! DCLK1_HUMAN-Phosphoserine726 [Term] id: CCO:B0030615 name: DCX_HUMAN def: "Neuronal migration protein doublecortin" [UniProtKB:O43602] synonym: "Doublin" EXACT [UniProtKB:O43602] synonym: "Lis-X" EXACT [UniProtKB:O43602] synonym: "Lissencephalin-X" EXACT [UniProtKB:O43602] xref: EMBL:AAC31696.1 xref: EMBL:AAC31797.1 xref: EMBL:AAC52037.1 xref: EMBL:AAH27925.1 xref: EMBL:CAA05867.1 xref: EMBL:CAA06617.1 xref: EMBL:CAA19966.3 xref: EMBL:CAI39488.2 xref: EMBL:CAI39489.1 xref: EMBL:CAI43156.1 xref: EMBL:EAX02644.1 xref: EMBL:EAX02645.1 xref: UniProtKB:A6NFY6 xref: UniProtKB:A9Z1V8 xref: UniProtKB:O43602 xref: UniProtKB:O43911 xref: UniProtKB:Q5JYZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017536 ! DCX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064664 ! DCX_HUMAN-Phosphothreonine95 relationship: transforms_into CCO:B0064665 ! DCX_HUMAN-Phosphotyrosine151 relationship: transforms_into CCO:B0064666 ! DCX_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0064667 ! DCX_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0064668 ! DCX_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0064669 ! DCX_HUMAN-Phosphoserine196 relationship: transforms_into CCO:B0064670 ! DCX_HUMAN-Phosphoserine346 relationship: transforms_into CCO:B0064671 ! DCX_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0064672 ! DCX_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0064673 ! DCX_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0064674 ! DCX_HUMAN-Phosphoserine398 relationship: transforms_into CCO:B0064675 ! DCX_HUMAN-Phosphothreonine402 relationship: transforms_into CCO:B0064676 ! DCX_HUMAN-Phosphoserine408 relationship: transforms_into CCO:B0064677 ! DCX_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0064678 ! DCX_HUMAN-Phosphothreonine412 relationship: transforms_into CCO:B0064679 ! DCX_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0064680 ! DCX_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0064681 ! DCX_HUMAN-Phosphoserine430 relationship: transforms_into CCO:B0064682 ! DCX_HUMAN-Phosphoserine436 [Term] id: CCO:B0030617 name: DCLK2_HUMAN def: "Serine/threonine-protein kinase DCLK2" [UniProtKB:Q8N568] synonym: "Doublecortin-like and CAM kinase-like 2" EXACT [UniProtKB:Q8N568] synonym: "Doublecortin-like kinase 2" EXACT [UniProtKB:Q8N568] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8N568] xref: EMBL:BAD92418.1 xref: EMBL:CAD39156.1 xref: UniProtKB:Q59GC8 xref: UniProtKB:Q8N399 xref: UniProtKB:Q8N568 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017533 ! DCLK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0030618 name: Q4W5L5_HUMAN def: "Putative uncharacterized protein MGC45428" [UniProtKB:Q4W5L5] xref: EMBL:AAY40983.1 xref: UniProtKB:Q4W5L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021122 ! MGC45428_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0030651 name: AMHR2_HUMAN def: "Anti-Muellerian hormone type-2 receptor precursor" [UniProtKB:Q16671] synonym: "AMH type II receptor" EXACT [UniProtKB:Q16671] synonym: "Anti-Muellerian hormone type II receptor" EXACT [UniProtKB:Q16671] synonym: "EC 2.7.11.30" EXACT [UniProtKB:Q16671] synonym: "MIS type II receptor" EXACT [UniProtKB:Q16671] synonym: "MISRII" EXACT [UniProtKB:Q16671] synonym: "MRII" EXACT [UniProtKB:Q16671] xref: EMBL:AAC50328.1 xref: EMBL:AAD48497.1 xref: EMBL:AAI26317.1 xref: EMBL:CAA61418.1 xref: EMBL:CAA62593.1 xref: UniProtKB:A0AVE1 xref: UniProtKB:Q13762 xref: UniProtKB:Q16671 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016961 ! AMHR2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001381 ! transmembrane receptor protein serine/threonine kinase signaling protein activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005682 ! hormone binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0030652 name: Q13161_HUMAN def: "Bone morphogenic protein type II receptor" [UniProtKB:Q13161] synonym: "Bone morphogenetic protein receptor, type II (Serine/threonine kinase), isoform CRA_a" EXACT [UniProtKB:Q13161] xref: EMBL:AAA86519.1 xref: EMBL:EAW70309.1 xref: UniProtKB:Q13161 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004173 ! BMPR2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway [Term] id: CCO:B0030691 name: Q6IAV4_HUMAN def: "DOC-1R protein" [UniProtKB:Q6IAV4] synonym: "CDK2-associated protein 2" EXACT [UniProtKB:Q6IAV4] synonym: "cDNA FLJ10636 fis, clone NT2RP2005675, highly similar to Cyclin-dependent kinase 2-associated protein 2" EXACT [UniProtKB:Q6IAV4] xref: EMBL:BAG50926.1 xref: EMBL:CAG33331.1 xref: EMBL:CAG46839.1 xref: EMBL:EAW74644.1 xref: UniProtKB:Q6IAV4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008750 ! DOC-1R_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020544 ! doc_1r-wars physical interaction [Term] id: CCO:B0030700 name: MDHM_HUMAN def: "Malate dehydrogenase, mitochondrial precursor" [UniProtKB:P40926] synonym: "EC 1.1.1.37" EXACT [UniProtKB:P40926] xref: EMBL:AAC03787.1 xref: EMBL:AAH01917.1 xref: EMBL:BAF83468.1 xref: EMBL:EAW71796.1 xref: UniProtKB:A8K414 xref: UniProtKB:O43682 xref: UniProtKB:P40926 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007818 ! MDH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020366 ! mdh2-wars physical interaction relationship: transforms_into CCO:B0035188 ! MDHM_HUMAN-Phosphotyrosine56 relationship: transforms_into CCO:B0035189 ! MDHM_HUMAN-N6-acetyllysine157 relationship: transforms_into CCO:B0035190 ! MDHM_HUMAN-N6-acetyllysine239 relationship: transforms_into CCO:B0035191 ! MDHM_HUMAN-N6-acetyllysine314 [Term] id: CCO:B0030726 name: TB22B_HUMAN def: "TBC1 domain family member 22B" [UniProtKB:Q9NU19] xref: EMBL:AAH00291.2 xref: EMBL:AAH00743.2 xref: EMBL:AAH01927.1 xref: EMBL:AAH02720.2 xref: EMBL:AAI09027.1 xref: EMBL:AAI09028.1 xref: EMBL:AAQ72548.1 xref: EMBL:BAA91099.1 xref: EMBL:CAH71194.1 xref: EMBL:CAI20318.1 xref: EMBL:CAI22620.1 xref: UniProtKB:Q32MQ8 xref: UniProtKB:Q5VUK9 xref: UniProtKB:Q7Z6P7 xref: UniProtKB:Q9BPV6 xref: UniProtKB:Q9BUT5 xref: UniProtKB:Q9NU19 xref: UniProtKB:Q9NXB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020157 ! TBC1D22B_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0030729 name: TB22A_HUMAN def: "TBC1 domain family member 22A" [UniProtKB:Q8WUA7] xref: EMBL:AAD12228.1 xref: EMBL:AAH01292.2 xref: EMBL:AAH02743.2 xref: EMBL:AAH20976.2 xref: EMBL:AAH29897.1 xref: EMBL:BAC86253.1 xref: EMBL:CAB46628.1 xref: EMBL:CAG30298.1 xref: EMBL:CAI17954.1 xref: EMBL:CAI18761.1 xref: EMBL:CAI21503.1 xref: EMBL:CAI22357.1 xref: EMBL:CAI23583.1 xref: EMBL:CAI23588.1 xref: UniProtKB:Q5TE47 xref: UniProtKB:Q6ZUH2 xref: UniProtKB:Q8WUA7 xref: UniProtKB:Q92680 xref: UniProtKB:Q9BVD6 xref: UniProtKB:Q9UGG0 xref: UniProtKB:Q9UGT2 xref: UniProtKB:Q9UGU6 xref: UniProtKB:Q9UH25 xref: UniProtKB:Q9Y4W5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020156 ! TBC1D22A_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0030742 name: IDE_HUMAN def: "Insulin-degrading enzyme" [UniProtKB:P14735] synonym: "EC 3.4.24.56" EXACT [UniProtKB:P14735] synonym: "Insulin protease" EXACT [UniProtKB:P14735] synonym: "Insulinase" EXACT [UniProtKB:P14735] synonym: "Insulysin" EXACT [UniProtKB:P14735] xref: EMBL:AAA52712.1 xref: EMBL:AAH96336.1 xref: EMBL:AAH96337.1 xref: EMBL:AAH96339.1 xref: EMBL:CAI13670.1 xref: EMBL:EAW50090.1 xref: UniProtKB:P14735 xref: UniProtKB:Q5T5N2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007647 ! IDE_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0000681 ! insulysin activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000359 ! peroxisome relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0030750 name: CSN3_HUMAN def: "COP9 signalosome complex subunit 3" [UniProtKB:Q9UNS2] synonym: "JAB1-containing signalosome subunit 3" EXACT [UniProtKB:Q9UNS2] synonym: "SGN3" EXACT [UniProtKB:Q9UNS2] synonym: "Signalosome subunit 3" EXACT [UniProtKB:Q9UNS2] xref: EMBL:AAC14197.1 xref: EMBL:AAD41247.1 xref: EMBL:AAH01891.1 xref: UniProtKB:O43191 xref: UniProtKB:Q7LDR6 xref: UniProtKB:Q9UNS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006401 ! COPS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008528 ! ddb1-cops3 physical interaction relationship: participates_in CCO:I0016271 ! ikk-csn3 physical interaction relationship: participates_in CCO:I0017684 ! raf1-cops3-1 physical interaction relationship: participates_in CCO:I0018053 ! araf-cops3 physical interaction relationship: participates_in CCO:I0018798 ! ikk-csn3-1 physical interaction relationship: participates_in CCO:I0018811 ! araf-cops3-1 physical interaction relationship: participates_in CCO:I0018820 ! araf-cops3-2 physical interaction relationship: participates_in CCO:I0019373 ! raf1-cops3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0030752 ! CSN3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0030753 ! CSN3_HUMAN-Phosphoserine410 [Term] id: CCO:B0030751 name: VAMP3_HUMAN def: "Vesicle-associated membrane protein 3" [UniProtKB:Q15836] synonym: "CEB" EXACT [UniProtKB:Q15836] synonym: "Cellubrevin" EXACT [UniProtKB:Q15836] synonym: "Synaptobrevin-3" EXACT [UniProtKB:Q15836] synonym: "VAMP-3" EXACT [UniProtKB:Q15836] xref: EMBL:AAB05814.1 xref: EMBL:AAH03570.1 xref: EMBL:AAH07050.1 xref: EMBL:AAP35991.1 xref: EMBL:CAB63146.1 xref: UniProtKB:Q15836 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006402 ! VAMP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008535 ! vamp3-ddb1 physical interaction relationship: participates_in CCO:I0020432 ! rdbp-vamp3 physical interaction relationship: transforms_into CCO:B0030754 ! VAMP3_HUMAN-Phosphoserine58 [Term] id: CCO:B0030752 name: CSN3_HUMAN-N-acetylalanine2 def: "Protein CSN3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9UNS2] xref: UniProtKB:Q9UNS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000530 ! signalosome relationship: transformation_of CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:B0030753 name: CSN3_HUMAN-Phosphoserine410 def: "Protein CSN3_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q9UNS2] xref: UniProtKB:Q9UNS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:B0030754 name: VAMP3_HUMAN-Phosphoserine58 def: "Protein VAMP3_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:Q15836] xref: UniProtKB:Q15836 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0030751 ! VAMP3_HUMAN [Term] id: CCO:B0030757 name: RIR2_HUMAN def: "Ribonucleoside-diphosphate reductase subunit M2" [UniProtKB:P31350] synonym: "EC 1.17.4.1" EXACT [UniProtKB:P31350] synonym: "Ribonucleotide reductase small chain" EXACT [UniProtKB:P31350] synonym: "Ribonucleotide reductase small subunit" EXACT [UniProtKB:P31350] xref: EMBL:AAA09577.1 xref: EMBL:AAH01886.1 xref: EMBL:AAH30154.1 xref: EMBL:AAK51163.1 xref: EMBL:AAX93099.1 xref: EMBL:CAA42181.1 xref: UniProtKB:P31350 xref: UniProtKB:Q5WRU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008108 ! RRM2_human relationship: has_function CCO:F0001113 ! ribonucleoside-diphosphate reductase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0035589 ! RIR2_HUMAN-Phosphoserine20 [Term] id: CCO:B0030758 name: RIR2B_HUMAN def: "Ribonucleoside-diphosphate reductase subunit M2 B" [UniProtKB:Q7LG56] synonym: "EC 1.17.4.1" EXACT [UniProtKB:Q7LG56] synonym: "p53-inducible ribonucleotide reductase small subunit 2-like protein" EXACT [UniProtKB:Q7LG56] synonym: "p53R2" EXACT [UniProtKB:Q7LG56] synonym: "TP53-inducible ribonucleotide reductase M2 B" EXACT [UniProtKB:Q7LG56] xref: EMBL:AAH42468.1 xref: EMBL:AAI08262.1 xref: EMBL:AAI17497.1 xref: EMBL:AAI30629.1 xref: EMBL:AAY29059.1 xref: EMBL:BAA92005.1 xref: EMBL:BAA92434.1 xref: EMBL:BAA92493.1 xref: EMBL:BAD11774.1 xref: EMBL:BAD11775.1 xref: EMBL:BAD12265.1 xref: EMBL:BAD12266.1 xref: EMBL:BAD12267.1 xref: EMBL:CAB70703.2 xref: UniProtKB:Q17R22 xref: UniProtKB:Q75PQ6 xref: UniProtKB:Q75PQ7 xref: UniProtKB:Q75PY8 xref: UniProtKB:Q75PY9 xref: UniProtKB:Q7LG56 xref: UniProtKB:Q86YE3 xref: UniProtKB:Q9NPD6 xref: UniProtKB:Q9NTD8 xref: UniProtKB:Q9NUW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008107 ! RRM2B_human relationship: has_function CCO:F0001113 ! ribonucleoside-diphosphate reductase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0030768 name: PSA7_HUMAN def: "Proteasome subunit alpha type-7" [UniProtKB:O14818] synonym: "EC 3.4.25.1" EXACT [UniProtKB:O14818] synonym: "Proteasome subunit RC6-1" EXACT [UniProtKB:O14818] synonym: "Proteasome subunit XAPC7" EXACT [UniProtKB:O14818] xref: EMBL:AAB81515.1 xref: EMBL:AAC99402.1 xref: EMBL:AAH04427.1 xref: EMBL:AAP35829.1 xref: EMBL:CAC04017.1 xref: EMBL:CAC04018.1 xref: UniProtKB:O14818 xref: UniProtKB:Q9BR53 xref: UniProtKB:Q9H4K5 xref: UniProtKB:Q9UEU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008019 ! PSMA7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008725 ! alpha1-alpha7 physical interaction relationship: participates_in CCO:I0008734 ! alpha4-alpha7 physical interaction relationship: participates_in CCO:I0008736 ! alpha6-alpha7 physical interaction relationship: participates_in CCO:I0008737 ! alpha7-alpha1 physical interaction relationship: participates_in CCO:I0008738 ! alpha7-alpha4 physical interaction relationship: participates_in CCO:I0008739 ! alpha7-alpha6 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035477 ! PSA7_HUMAN-N-acetylserine2 [Term] id: CCO:B0030784 name: FUSIP_HUMAN def: "FUS-interacting serine-arginine-rich protein 1" [UniProtKB:O75494] synonym: "40 kDa SR-repressor protein" EXACT [UniProtKB:O75494] synonym: "Splicing factor SRp38" EXACT [UniProtKB:O75494] synonym: "SRrp40" EXACT [UniProtKB:O75494] synonym: "TASR" EXACT [UniProtKB:O75494] synonym: "TLS-associated protein with Ser-Arg repeats" EXACT [UniProtKB:O75494] synonym: "TLS-associated protein with SR repeats" EXACT [UniProtKB:O75494] synonym: "TLS-associated serine-arginine protein" EXACT [UniProtKB:O75494] synonym: "TLS-associated SR protein" EXACT [UniProtKB:O75494] xref: EMBL:AAC26727.1 xref: EMBL:AAC70918.1 xref: EMBL:AAH01107.1 xref: EMBL:AAH05039.1 xref: EMBL:AAH10074.1 xref: EMBL:AAL06098.1 xref: EMBL:AAL06099.1 xref: EMBL:AAL16665.1 xref: EMBL:AAL16666.1 xref: EMBL:AAL57514.1 xref: EMBL:AAN65380.1 xref: EMBL:AAN65381.1 xref: EMBL:BAA91601.1 xref: EMBL:CAI14803.1 xref: EMBL:CAI14805.1 xref: EMBL:CAI14808.1 xref: UniProtKB:A6NFM6 xref: UniProtKB:A6NI42 xref: UniProtKB:A6NIU7 xref: UniProtKB:O60572 xref: UniProtKB:O75494 xref: UniProtKB:Q5JRH9 xref: UniProtKB:Q5JRI2 xref: UniProtKB:Q5JRI4 xref: UniProtKB:Q96G09 xref: UniProtKB:Q96P17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017848 ! FUSIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002768 ! negative regulation of nuclear mRNA splicing, via spliceosome relationship: transforms_into CCO:B0066305 ! FUSIP_HUMAN-Phosphotyrosine110 relationship: transforms_into CCO:B0066306 ! FUSIP_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0066307 ! FUSIP_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0066308 ! FUSIP_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0066309 ! FUSIP_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0066310 ! FUSIP_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0066311 ! FUSIP_HUMAN-Phosphoserine160 relationship: transforms_into CCO:B0066312 ! FUSIP_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0066313 ! FUSIP_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0066314 ! FUSIP_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0066315 ! FUSIP_HUMAN-Phosphothreonine255 relationship: transforms_into CCO:B0066316 ! FUSIP_HUMAN-Phosphoserine256 [Term] id: CCO:B0030800 name: PSB2_HUMAN def: "Proteasome subunit beta type-2" [UniProtKB:P49721] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P49721] synonym: "Macropain subunit C7-I" EXACT [UniProtKB:P49721] synonym: "Multicatalytic endopeptidase complex subunit C7-I" EXACT [UniProtKB:P49721] synonym: "Proteasome component C7-I" EXACT [UniProtKB:P49721] xref: EMBL:AAI01837.1 xref: EMBL:AAI05127.1 xref: EMBL:AAI07902.1 xref: EMBL:AAP35801.1 xref: EMBL:BAA05646.1 xref: EMBL:CAC36031.2 xref: EMBL:CAG33143.1 xref: EMBL:CAI22074.1 xref: EMBL:CAI23521.1 xref: UniProtKB:P31145 xref: UniProtKB:P49721 xref: UniProtKB:Q9BWZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008021 ! PSMB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008710 ! traf6-psmb2 physical interaction relationship: participates_in CCO:I0008726 ! alpha1-beta2 physical interaction relationship: participates_in CCO:I0008740 ! beta2-beta3 physical interaction relationship: participates_in CCO:I0008749 ! beta3-beta2 physical interaction relationship: participates_in CCO:I0008751 ! beta5-beta2 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035479 ! PSB2_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0030804 name: PSB8_HUMAN def: "Proteasome subunit beta type-8 precursor" [UniProtKB:P28062] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P28062] synonym: "Macropain subunit C13" EXACT [UniProtKB:P28062] synonym: "Multicatalytic endopeptidase complex subunit C13" EXACT [UniProtKB:P28062] synonym: "Proteasome component C13" EXACT [UniProtKB:P28062] synonym: "Proteasome subunit beta-5i" EXACT [UniProtKB:P28062] xref: EMBL:AAA56777.1 xref: EMBL:AAA56778.1 xref: EMBL:AAA80234.1 xref: EMBL:AAA80235.1 xref: EMBL:AAH01114.1 xref: EMBL:CAA44482.1 xref: EMBL:CAA47026.1 xref: EMBL:CAA60786.1 xref: EMBL:CAA60787.1 xref: EMBL:CAA78705.1 xref: EMBL:CAA78706.1 xref: EMBL:CAI18139.1 xref: UniProtKB:P28062 xref: UniProtKB:Q29824 xref: UniProtKB:Q96J48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011632 ! PSMB8_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008721 ! lsm1-psmb8 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0030806 name: PSB5_HUMAN def: "Proteasome subunit beta type-5 precursor" [UniProtKB:P28074] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P28074] synonym: "Macropain epsilon chain" EXACT [UniProtKB:P28074] synonym: "Multicatalytic endopeptidase complex epsilon chain" EXACT [UniProtKB:P28074] synonym: "Proteasome chain 6" EXACT [UniProtKB:P28074] synonym: "Proteasome epsilon chain" EXACT [UniProtKB:P28074] synonym: "Proteasome subunit MB1" EXACT [UniProtKB:P28074] synonym: "Proteasome subunit X" EXACT [UniProtKB:P28074] xref: EMBL:AAB33092.1 xref: EMBL:AAH57840.1 xref: EMBL:AAI07721.1 xref: EMBL:AAP35423.1 xref: EMBL:BAA06097.1 xref: EMBL:CAA64838.1 xref: EMBL:CAD97956.1 xref: UniProtKB:P28074 xref: UniProtKB:Q16242 xref: UniProtKB:Q6PEW2 xref: UniProtKB:Q7Z3B5 xref: UniProtKB:Q9TNN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011631 ! PSMB5_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008713 ! traf6-psmb5 physical interaction relationship: participates_in CCO:I0008722 ! lsm1-psmb5 physical interaction relationship: participates_in CCO:I0008743 ! beta1-beta5 physical interaction relationship: participates_in CCO:I0008750 ! beta5-beta1 physical interaction relationship: participates_in CCO:I0008751 ! beta5-beta2 physical interaction relationship: participates_in CCO:I0008752 ! beta5-beta3 physical interaction relationship: participates_in CCO:I0008753 ! beta5-alpha3 physical interaction relationship: participates_in CCO:I0008754 ! beta5-beta7 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0030810 name: Q5JNW7_HUMAN def: "Proteasome (Prosome, macropain) subunit, beta type, 8 (Large multifunctional peptidase 7) (Large multifunctional protease 7)" [UniProtKB:Q5JNW7] xref: EMBL:CAI18624.1 xref: EMBL:CAM24978.1 xref: EMBL:CAM25484.1 xref: EMBL:CAM25946.1 xref: EMBL:CAM26260.1 xref: EMBL:CAQ07780.1 xref: EMBL:CAQ08446.1 xref: EMBL:CAQ08493.1 xref: UniProtKB:Q5JNW7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011632 ! PSMB8_human relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008744 ! beta1-beta5i physical interaction relationship: participates_in CCO:I0008746 ! beta1i-beta5i physical interaction relationship: participates_in CCO:I0008755 ! beta5i-beta7 physical interaction relationship: participates_in CCO:I0008759 ! beta7-beta5i physical interaction [Term] id: CCO:B0030838 name: OPTN_HUMAN def: "Optineurin" [UniProtKB:Q96CV9] synonym: "E3-14.7K-interacting protein" EXACT [UniProtKB:Q96CV9] synonym: "FIP-2" EXACT [UniProtKB:Q96CV9] synonym: "Huntingtin yeast partner L" EXACT [UniProtKB:Q96CV9] synonym: "Huntingtin-interacting protein L" EXACT [UniProtKB:Q96CV9] synonym: "NEMO-related protein" EXACT [UniProtKB:Q96CV9] synonym: "Optic neuropathy-inducing protein" EXACT [UniProtKB:Q96CV9] synonym: "TFIIIA-IntP" EXACT [UniProtKB:Q96CV9] synonym: "Transcription factor IIIA-interacting protein" EXACT [UniProtKB:Q96CV9] xref: EMBL:AAC16046.1 xref: EMBL:AAC16047.1 xref: EMBL:AAC26850.1 xref: EMBL:AAG00497.1 xref: EMBL:AAH13876.1 xref: EMBL:AAH32762.1 xref: EMBL:AAL76327.1 xref: EMBL:AAL76328.1 xref: EMBL:AAL76329.1 xref: EMBL:CAI16549.1 xref: EMBL:CAI16550.1 xref: EMBL:CAI16551.1 xref: EMBL:CAI16552.1 xref: UniProtKB:Q5T672 xref: UniProtKB:Q5T673 xref: UniProtKB:Q5T674 xref: UniProtKB:Q5T675 xref: UniProtKB:Q7LDL9 xref: UniProtKB:Q8N562 xref: UniProtKB:Q96CV9 xref: UniProtKB:Q9UET9 xref: UniProtKB:Q9UEV4 xref: UniProtKB:Q9Y218 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019056 ! OPTN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015792 ! optn-tbc1d17 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068976 ! OPTN_HUMAN-Phosphoserine170 relationship: transforms_into CCO:B0068977 ! OPTN_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0068978 ! OPTN_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0068979 ! OPTN_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0068980 ! OPTN_HUMAN-Phosphoserine177 [Term] id: CCO:B0030841 name: Q7Z7F1_HUMAN def: "Inhibitor of kappaB kinase gamma" [UniProtKB:Q7Z7F1] xref: EMBL:AAM44073.1 xref: UniProtKB:Q7Z7F1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005183 ! IKBKG_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0016538 ! ikbkg-ikbkg-1 physical interaction [Term] id: CCO:B0030887 name: PSD13_HUMAN def: "26S proteasome non-ATPase regulatory subunit 13" [UniProtKB:Q9UNM6] synonym: "26S proteasome regulatory subunit p40.5" EXACT [UniProtKB:Q9UNM6] synonym: "26S proteasome regulatory subunit S11" EXACT [UniProtKB:Q9UNM6] xref: EMBL:AAC64104.1 xref: EMBL:AAD43442.1 xref: EMBL:AAH01100.1 xref: EMBL:AAH01747.1 xref: EMBL:BAA33214.1 xref: UniProtKB:O75831 xref: UniProtKB:Q9UNM6 xref: UniProtKB:Q9UNV3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008026 ! PSMD13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016535 ! ikbkg-psmd13 physical interaction relationship: participates_in CCO:I0017204 ! traf6-psmd13 physical interaction relationship: transforms_into CCO:B0035482 ! PSD13_HUMAN-Phosphoserine106 [Term] id: CCO:B0030905 name: PRS10_HUMAN def: "26S protease regulatory subunit S10B" [UniProtKB:P62333] synonym: "Proteasome 26S subunit ATPase 6" EXACT [UniProtKB:P62333] synonym: "Proteasome subunit p42" EXACT [UniProtKB:P62333] xref: EMBL:AAB61616.1 xref: EMBL:AAH05390.1 xref: EMBL:AAP35489.1 xref: EMBL:BAA11338.1 xref: EMBL:CAG32990.1 xref: UniProtKB:P49719 xref: UniProtKB:P62333 xref: UniProtKB:Q6IBU3 xref: UniProtKB:Q92524 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011629 ! PSMC6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008689 ! flj38984-psmc6 physical interaction relationship: participates_in CCO:I0008691 ! psmc6-psmd9 physical interaction relationship: participates_in CCO:I0008707 ! traf6-psmc6 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0039597 ! PRS10_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0069560 ! PRS10_HUMAN-Phosphotyrosine207 [Term] id: CCO:B0030929 name: PSB3_HUMAN def: "Proteasome subunit beta type-3" [UniProtKB:P49720] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P49720] synonym: "Proteasome chain 13" EXACT [UniProtKB:P49720] synonym: "Proteasome component C10-II" EXACT [UniProtKB:P49720] synonym: "Proteasome theta chain" EXACT [UniProtKB:P49720] xref: EMBL:AAH02570.1 xref: EMBL:AAH13008.1 xref: EMBL:BAA05645.1 xref: UniProtKB:P31147 xref: UniProtKB:P49720 xref: UniProtKB:Q0P6J7 xref: UniProtKB:Q96E27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008022 ! PSMB3_human relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008740 ! beta2-beta3 physical interaction relationship: participates_in CCO:I0008741 ! beta1-beta3 physical interaction relationship: participates_in CCO:I0008747 ! beta2i-beta3 physical interaction relationship: participates_in CCO:I0008748 ! beta3-beta2i physical interaction relationship: participates_in CCO:I0008749 ! beta3-beta2 physical interaction relationship: participates_in CCO:I0008752 ! beta5-beta3 physical interaction relationship: participates_in CCO:I0008757 ! beta7-beta3 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035480 ! PSB3_HUMAN-N-acetylserine2 [Term] id: CCO:B0030933 name: DNA2L_HUMAN def: "DNA2-like helicase" [UniProtKB:P51530] synonym: "DNA replication ATP-dependent helicase-like homolog" EXACT [UniProtKB:P51530] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P51530] xref: EMBL:AAH41115.1 xref: EMBL:AAH53574.1 xref: EMBL:AAH63664.1 xref: EMBL:AAI11741.1 xref: EMBL:BAA07647.1 xref: EMBL:CAI17238.1 xref: UniProtKB:P51530 xref: UniProtKB:Q2NKM1 xref: UniProtKB:Q5TC49 xref: UniProtKB:Q6P455 xref: UniProtKB:Q6PI80 xref: UniProtKB:Q7Z6H9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007463 ! DNA2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0030954 name: RPB4_HUMAN def: "DNA-directed RNA polymerase II subunit RPB4" [UniProtKB:O15514] synonym: "DNA-directed RNA polymerase II 16 kDa polypeptide" EXACT [UniProtKB:O15514] synonym: "DNA-directed RNA polymerase II subunit D" EXACT [UniProtKB:O15514] synonym: "RNA polymerase II subunit B4" EXACT [UniProtKB:O15514] xref: EMBL:AAC52056.1 xref: EMBL:AAC80226.1 xref: EMBL:AAH17205.1 xref: EMBL:AAH93795.1 xref: EMBL:AAH93797.1 xref: UniProtKB:O15514 xref: UniProtKB:Q52LT4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008123 ! POLR2D_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction [Term] id: CCO:B0030961 name: PSB1_HUMAN def: "Proteasome subunit beta type-1 precursor" [UniProtKB:P20618] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P20618] synonym: "Macropain subunit C5" EXACT [UniProtKB:P20618] synonym: "Multicatalytic endopeptidase complex subunit C5" EXACT [UniProtKB:P20618] synonym: "Proteasome component C5" EXACT [UniProtKB:P20618] synonym: "Proteasome gamma chain" EXACT [UniProtKB:P20618] xref: EMBL:AAH00508.1 xref: EMBL:AAH20807.1 xref: EMBL:AAV38525.1 xref: EMBL:BAA00658.1 xref: EMBL:CAA20287.1 xref: UniProtKB:P20618 xref: UniProtKB:Q9BWA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008020 ! PSMB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008741 ! beta1-beta3 physical interaction relationship: participates_in CCO:I0008742 ! beta1-beta7 physical interaction relationship: participates_in CCO:I0008743 ! beta1-beta5 physical interaction relationship: participates_in CCO:I0008744 ! beta1-beta5i physical interaction relationship: participates_in CCO:I0008750 ! beta5-beta1 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035478 ! PSB1_HUMAN-Phosphotyrosine150 [Term] id: CCO:B0030969 name: RS3_HUMAN def: "40S ribosomal protein S3" [UniProtKB:P23396] xref: EMBL:AAA18095.1 xref: EMBL:AAB19349.2 xref: EMBL:AAB60336.1 xref: EMBL:AAB60337.1 xref: EMBL:AAB60338.1 xref: EMBL:AAH03137.1 xref: EMBL:AAH03577.1 xref: EMBL:AAH13196.1 xref: EMBL:AAH34149.1 xref: EMBL:AAH71917.1 xref: EMBL:AAI00285.1 xref: EMBL:AAV40835.1 xref: EMBL:BAB79476.1 xref: EMBL:BAB93471.1 xref: EMBL:CAA39248.1 xref: UniProtKB:P23396 xref: UniProtKB:Q498B5 xref: UniProtKB:Q8NI95 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008133 ! RPS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016508 ! ikbkg-rps3 physical interaction relationship: participates_in CCO:I0016788 ! nfkb2-rps3 physical interaction relationship: participates_in CCO:I0016996 ! tnfrsf1a-rps3 physical interaction relationship: participates_in CCO:I0017064 ! tradd-rps3 physical interaction relationship: participates_in CCO:I0017092 ! traf1-rps3 physical interaction relationship: transforms_into CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: transforms_into CCO:B0035605 ! RS3_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0070211 ! RS3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0070212 ! RS3_HUMAN-Phosphothreonine220 [Term] id: CCO:B0030971 name: IRK11_HUMAN def: "ATP-sensitive inward rectifier potassium channel 11" [UniProtKB:Q14654] synonym: "IKATP" EXACT [UniProtKB:Q14654] synonym: "Inward rectifier K(+) channel Kir6.2" EXACT [UniProtKB:Q14654] synonym: "Potassium channel, inwardly rectifying subfamily J member 11" EXACT [UniProtKB:Q14654] xref: EMBL:AAH64497.1 xref: EMBL:AAI12359.1 xref: EMBL:BAA09131.1 xref: UniProtKB:Q14654 xref: UniProtKB:Q2M1H7 xref: UniProtKB:Q58EX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018315 ! KCNJ11_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001510 ! inward rectifier potassium channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0002729 ! ATP-activated inward rectifier potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000540 ! ATP-sensitive potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001002 ! T-tubule relationship: located_in CCO:C0001638 ! sarcolemma relationship: participates_in CCO:P0002733 ! negative regulation of insulin secretion relationship: participates_in CCO:P0002956 ! regulation of insulin secretion [Term] id: CCO:B0030995 name: IRK2_HUMAN def: "Inward rectifier potassium channel 2" [UniProtKB:P63252] synonym: "Cardiac inward rectifier potassium channel" EXACT [UniProtKB:P63252] synonym: "Inward rectifier K(+) channel Kir2.1" EXACT [UniProtKB:P63252] synonym: "IRK1" EXACT [UniProtKB:P63252] synonym: "Potassium channel, inwardly rectifying subfamily J member 2" EXACT [UniProtKB:P63252] xref: EMBL:AAA64282.1 xref: EMBL:AAA91781.1 xref: EMBL:AAB50277.1 xref: EMBL:AAB88797.1 xref: EMBL:AAC39555.1 xref: EMBL:AAC50072.1 xref: EMBL:AAF73241.1 xref: EMBL:AAF73242.1 xref: UniProtKB:O15110 xref: UniProtKB:P48049 xref: UniProtKB:P63252 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022342 ! KCNJ2_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001510 ! inward rectifier potassium channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002729 ! ATP-activated inward rectifier potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016310 ! irk2-akap5-3 physical interaction relationship: participates_in CCO:I0019500 ! irk2-flna-3 physical interaction relationship: transforms_into CCO:B0067153 ! IRK2_HUMAN-Phosphotyrosine337 [Term] id: CCO:B0031003 name: PSD7_HUMAN def: "26S proteasome non-ATPase regulatory subunit 7" [UniProtKB:P51665] synonym: "26S proteasome regulatory subunit rpn8" EXACT [UniProtKB:P51665] synonym: "26S proteasome regulatory subunit S12" EXACT [UniProtKB:P51665] synonym: "Mov34 protein homolog" EXACT [UniProtKB:P51665] synonym: "Proteasome subunit p40" EXACT [UniProtKB:P51665] xref: EMBL:AAH00338.1 xref: EMBL:AAH12606.1 xref: EMBL:BAA08780.1 xref: UniProtKB:P51665 xref: UniProtKB:Q6PKI2 xref: UniProtKB:Q96E97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008027 ! PSMD7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008719 ! traf6-psmd7 physical interaction relationship: participates_in CCO:I0008824 ! rab1a-psmd7 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035483 ! PSD7_HUMAN-Phosphothreonine186 [Term] id: CCO:B0031007 name: PSB9_HUMAN def: "Proteasome subunit beta type-9 precursor" [UniProtKB:P28065] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P28065] synonym: "Low molecular mass protein 2" EXACT [UniProtKB:P28065] synonym: "Macropain chain 7" EXACT [UniProtKB:P28065] synonym: "Multicatalytic endopeptidase complex chain 7" EXACT [UniProtKB:P28065] synonym: "Proteasome chain 7" EXACT [UniProtKB:P28065] synonym: "Proteasome subunit beta-1i" EXACT [UniProtKB:P28065] synonym: "RING12 protein" EXACT [UniProtKB:P28065] xref: EMBL:AAC50154.1 xref: EMBL:AAC60646.1 xref: EMBL:AAH65513.1 xref: EMBL:CAA44603.1 xref: EMBL:CAA47024.1 xref: EMBL:CAA60784.1 xref: EMBL:CAA78700.1 xref: EMBL:CAI18141.1 xref: UniProtKB:P28065 xref: UniProtKB:Q16523 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008025 ! PSMB9_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008745 ! beta1i-beta7 physical interaction relationship: participates_in CCO:I0008746 ! beta1i-beta5i physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0031015 name: PSB6_HUMAN def: "Proteasome subunit beta type-6 precursor" [UniProtKB:P28072] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P28072] synonym: "Macropain delta chain" EXACT [UniProtKB:P28072] synonym: "Multicatalytic endopeptidase complex delta chain" EXACT [UniProtKB:P28072] synonym: "Proteasome delta chain" EXACT [UniProtKB:P28072] synonym: "Proteasome subunit Y" EXACT [UniProtKB:P28072] xref: EMBL:AAH00835.1 xref: EMBL:BAA06098.1 xref: EMBL:CAA43963.1 xref: UniProtKB:P28072 xref: UniProtKB:Q96J55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008023 ! PSMB6_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008705 ! traf6-psmb6 physical interaction relationship: participates_in CCO:I0008756 ! beta6-beta7 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:I0008804 ! ezh2-psmb6 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0031064 name: LIMD1_HUMAN def: "LIM domain-containing protein 1" [UniProtKB:Q9UGP4] xref: EMBL:AAI17237.1 xref: EMBL:AAI17239.1 xref: EMBL:CAB63652.1 xref: EMBL:CAB95944.1 xref: EMBL:CAC35917.1 xref: UniProtKB:Q17RQ1 xref: UniProtKB:Q9BQQ9 xref: UniProtKB:Q9NQ47 xref: UniProtKB:Q9UGP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007779 ! LIMD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035098 ! LIMD1_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0035099 ! LIMD1_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0067667 ! LIMD1_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0067668 ! LIMD1_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0067669 ! LIMD1_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0067670 ! LIMD1_HUMAN-Phosphoserine424 [Term] id: CCO:B0031065 name: FBLI1_HUMAN def: "Filamin-binding LIM protein 1" [UniProtKB:Q8WUP2] synonym: "FBLP-1" EXACT [UniProtKB:Q8WUP2] synonym: "MIG2-interacting protein" EXACT [UniProtKB:Q8WUP2] synonym: "Migfilin" EXACT [UniProtKB:Q8WUP2] synonym: "Mitogen-inducible 2-interacting protein" EXACT [UniProtKB:Q8WUP2] xref: EMBL:AAH19895.1 xref: EMBL:AAO15549.1 xref: EMBL:AAO49012.1 xref: EMBL:BAB55115.1 xref: EMBL:CAB61365.1 xref: EMBL:CAH70853.1 xref: EMBL:CAH70854.1 xref: UniProtKB:Q5VVE0 xref: UniProtKB:Q5VVE1 xref: UniProtKB:Q8IX23 xref: UniProtKB:Q8WUP2 xref: UniProtKB:Q96T00 xref: UniProtKB:Q9UFD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007526 ! FBLIM1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:P0000822 ! regulation of cell shape [Term] id: CCO:B0031066 name: MKX_HUMAN def: "Homeobox protein Mohawk" [UniProtKB:Q8IYA7] xref: EMBL:AAH36207.1 xref: UniProtKB:Q8IYA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018635 ! MKX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031067 name: IRX5_HUMAN def: "Iroquois-class homeodomain protein IRX-5" [UniProtKB:P78411] synonym: "Homeodomain protein IRXB2" EXACT [UniProtKB:P78411] synonym: "Iroquois homeobox protein 5" EXACT [UniProtKB:P78411] synonym: "IRX-2A" EXACT [UniProtKB:P78411] xref: EMBL:AAB50002.1 xref: EMBL:AAB50007.1 xref: EMBL:AAQ16550.1 xref: EMBL:AAQ16551.1 xref: UniProtKB:P78411 xref: UniProtKB:P78416 xref: UniProtKB:Q7Z2E1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018322 ! IRX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031069 name: IRX2_HUMAN def: "Iroquois-class homeodomain protein IRX-2" [UniProtKB:Q9BZI1] synonym: "Homeodomain protein IRXA2" EXACT [UniProtKB:Q9BZI1] synonym: "Iroquois homeobox protein 2" EXACT [UniProtKB:Q9BZI1] xref: EMBL:AAH65189.1 xref: EMBL:AAK01202.1 xref: EMBL:AAQ16545.1 xref: EMBL:AAQ16546.1 xref: UniProtKB:Q7Z2I7 xref: UniProtKB:Q9BZI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018319 ! IRX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031070 name: IRX3_HUMAN def: "Iroquois-class homeodomain protein IRX-3" [UniProtKB:P78415] synonym: "Homeodomain protein IRXB1" EXACT [UniProtKB:P78415] synonym: "Iroquois homeobox protein 3" EXACT [UniProtKB:P78415] xref: EMBL:AAB50006.1 xref: EMBL:AAH23667.1 xref: EMBL:AAQ16548.1 xref: EMBL:AAQ16549.1 xref: UniProtKB:P78415 xref: UniProtKB:Q7Z4A4 xref: UniProtKB:Q7Z4A5 xref: UniProtKB:Q8IVC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018320 ! IRX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031071 name: IRX1_HUMAN def: "Iroquois-class homeodomain protein IRX-1" [UniProtKB:P78414] synonym: "Homeodomain protein IRXA1" EXACT [UniProtKB:P78414] synonym: "Iroquois homeobox protein 1" EXACT [UniProtKB:P78414] xref: EMBL:AAB50005.1 xref: EMBL:AAH29160.1 xref: EMBL:AAQ16544.1 xref: EMBL:AAQ16553.1 xref: UniProtKB:P78414 xref: UniProtKB:Q7Z2F8 xref: UniProtKB:Q8N312 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018318 ! IRX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031117 name: Q4LE74_HUMAN def: "MYO9B variant protein" [UniProtKB:Q4LE74] xref: EMBL:BAE06079.1 xref: UniProtKB:Q4LE74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011869 ! MYO9B variant protein_human relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000788 ! myosin complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0031122 name: MYO9B_HUMAN def: "Myosin-IXb" [UniProtKB:Q13459] synonym: "Unconventional myosin-9b" EXACT [UniProtKB:Q13459] xref: EMBL:AAC26597.1 xref: EMBL:AAC50402.1 xref: EMBL:AAF00119.1 xref: EMBL:BAA92132.1 xref: UniProtKB:O75314 xref: UniProtKB:Q13459 xref: UniProtKB:Q9NUJ2 xref: UniProtKB:Q9UHN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011551 ! MYO9B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020376 ! muf1-myo9b physical interaction relationship: participates_in CCO:I0020635 ! prei3-myo9b physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0039545 ! MYO9B_HUMAN-Phosphoserine1267 relationship: transforms_into CCO:B0039546 ! MYO9B_HUMAN-Phosphothreonine1271 relationship: transforms_into CCO:B0039547 ! MYO9B_HUMAN-Phosphothreonine1348 relationship: transforms_into CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: transforms_into CCO:B0043334 ! MYO9B_HUMAN-Phosphoserine1290 relationship: transforms_into CCO:B0043335 ! MYO9B_HUMAN-Phosphothreonine1346 relationship: transforms_into CCO:B0068398 ! MYO9B_HUMAN-Phosphoserine716 relationship: transforms_into CCO:B0068399 ! MYO9B_HUMAN-Phosphoserine1354 [Term] id: CCO:B0031198 name: MOBL3_HUMAN def: "Mps one binder kinase activator-like 3" [UniProtKB:Q9Y3A3] synonym: "2C4D" EXACT [UniProtKB:Q9Y3A3] synonym: "Class II mMOB1" EXACT [UniProtKB:Q9Y3A3] synonym: "Mob1 homolog 3" EXACT [UniProtKB:Q9Y3A3] synonym: "Mob3" EXACT [UniProtKB:Q9Y3A3] synonym: "Preimplantation protein 3" EXACT [UniProtKB:Q9Y3A3] xref: EMBL:AAD34090.1 xref: EMBL:AAG44567.1 xref: EMBL:AAH05237.1 xref: EMBL:AAP97221.1 xref: EMBL:BAB15635.1 xref: EMBL:BAB19057.1 xref: EMBL:CAB45697.1 xref: EMBL:CAE45270.1 xref: EMBL:CAG33652.1 xref: UniProtKB:Q7Z4Y6 xref: UniProtKB:Q9H2P3 xref: UniProtKB:Q9H5J1 xref: UniProtKB:Q9Y3A3 xref: UniProtKB:Q9Y4T8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006414 ! MOBKL3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008152 ! prei3-mcm2 physical interaction relationship: participates_in CCO:I0008153 ! prei3-rif1 physical interaction relationship: participates_in CCO:I0008299 ! prei3-ube2v2 physical interaction relationship: participates_in CCO:I0008491 ! prei3-stk11 physical interaction relationship: participates_in CCO:I0014975 ! arhgef15-prei3 physical interaction relationship: participates_in CCO:I0020124 ! prei3-med31 physical interaction relationship: participates_in CCO:I0020125 ! prei3-gdf9 physical interaction relationship: participates_in CCO:I0020126 ! prei3-scmh1 physical interaction relationship: participates_in CCO:I0020127 ! prei3-setdb1 physical interaction relationship: participates_in CCO:I0020411 ! prei3-fadd physical interaction relationship: participates_in CCO:I0020412 ! prei3-mgc5309 physical interaction relationship: participates_in CCO:I0020633 ! prei3-egln2 physical interaction relationship: participates_in CCO:I0020634 ! prei3-elk1 physical interaction relationship: participates_in CCO:I0020635 ! prei3-myo9b physical interaction [Term] id: CCO:B0031284 name: 1433F_HUMAN-Phosphotyrosine117 def: "Protein 1433F_HUMAN with the residue 117 substituted with Phosphotyrosine" [UniProtKB:Q04917] comment: By similarity xref: UniProtKB:Q04917 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:B0031285 name: 1433G_HUMAN-Phosphotyrosine117 def: "Protein 1433G_HUMAN with the residue 117 substituted with Phosphotyrosine" [UniProtKB:P61981] comment: By similarity xref: UniProtKB:P61981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005489 ! 1433G_HUMAN [Term] id: CCO:B0031286 name: ABI1_HUMAN-Phosphotyrosine455 def: "Protein ABI1_HUMAN with the residue 455 substituted with Phosphotyrosine" [UniProtKB:Q8IZP0] comment: By similarity xref: UniProtKB:Q8IZP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:B0031287 name: ADT2_HUMAN-Phosphotyrosine191 def: "Protein ADT2_HUMAN with the residue 191 substituted with Phosphotyrosine" [UniProtKB:P05141] xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0031288 name: ADT2_HUMAN-Phosphotyrosine195 def: "Protein ADT2_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:P05141] xref: UniProtKB:P05141 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:B0031289 name: AF1L2_HUMAN-Phosphotyrosine56 def: "Protein AF1L2_HUMAN with the residue 56 substituted with Phosphotyrosine" [UniProtKB:Q8N4X5] comment: By similarity xref: UniProtKB:Q8N4X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001964 ! AF1L2_HUMAN [Term] id: CCO:B0031290 name: ANC2_HUMAN-Phosphotyrosine810 def: "Protein ANC2_HUMAN with the residue 810 substituted with Phosphotyrosine" [UniProtKB:Q9UJX6] comment: By similarity xref: UniProtKB:Q9UJX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002216 ! ANC2_HUMAN [Term] id: CCO:B0031291 name: ANXA6_HUMAN-Phosphotyrosine30 def: "Protein ANXA6_HUMAN with the residue 30 substituted with Phosphotyrosine" [UniProtKB:P08133] xref: UniProtKB:P08133 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005731 ! ANXA6_HUMAN [Term] id: CCO:B0031292 name: ANXA6_HUMAN-Phosphotyrosine201 def: "Protein ANXA6_HUMAN with the residue 201 substituted with Phosphotyrosine" [UniProtKB:P08133] comment: By similarity xref: UniProtKB:P08133 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005731 ! ANXA6_HUMAN [Term] id: CCO:B0031293 name: AP2B1_HUMAN-Phosphotyrosine888 def: "Protein AP2B1_HUMAN with the residue 888 substituted with Phosphotyrosine" [UniProtKB:P63010] xref: UniProtKB:P63010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005197 ! AP2B1_HUMAN [Term] id: CCO:B0031294 name: ARPC3_HUMAN-Phosphotyrosine47 def: "Protein ARPC3_HUMAN with the residue 47 substituted with Phosphotyrosine" [UniProtKB:O15145] xref: UniProtKB:O15145 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006172 ! ARPC3_HUMAN [Term] id: CCO:B0031295 name: AT1A1_HUMAN-Phosphotyrosine260 def: "Protein AT1A1_HUMAN with the residue 260 substituted with Phosphotyrosine" [UniProtKB:P05023] xref: UniProtKB:P05023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005459 ! AT1A1_HUMAN [Term] id: CCO:B0031296 name: AT1B1_HUMAN-Phosphotyrosine101 def: "Protein AT1B1_HUMAN with the residue 101 substituted with Phosphotyrosine" [UniProtKB:P05026] comment: By similarity xref: UniProtKB:P05026 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001603 ! sodium:potassium-exchanging ATPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000447 ! sodium:potassium-exchanging ATPase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: transformation_of CCO:B0005453 ! AT1B1_HUMAN [Term] id: CCO:B0031297 name: BCR_HUMAN-Phosphoserine236 def: "Protein BCR_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:P11274] comment: By similarity xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0031298 name: BCR_HUMAN-Phosphotyrosine246 def: "Protein BCR_HUMAN with the residue 246 substituted with Phosphotyrosine" [UniProtKB:P11274] comment: By similarity xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0031299 name: BEGIN_HUMAN-Phosphotyrosine137 def: "Protein BEGIN_HUMAN with the residue 137 substituted with Phosphotyrosine" [UniProtKB:Q9BUH8] comment: By similarity xref: UniProtKB:Q9BUH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:B0031300 name: CBL_HUMAN-Phosphoserine668 def: "Protein CBL_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:P22681] comment: By similarity xref: UniProtKB:P22681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:B0031301 name: CCNC_HUMAN-Phosphoserine121 def: "Protein CCNC_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:P24863] xref: UniProtKB:P24863 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001553 ! CCNC_HUMAN [Term] id: CCO:B0031302 name: CCNC_HUMAN-Phosphotyrosine122 def: "Protein CCNC_HUMAN with the residue 122 substituted with Phosphotyrosine" [UniProtKB:P24863] xref: UniProtKB:P24863 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001553 ! CCNC_HUMAN [Term] id: CCO:B0031303 name: CCNC_HUMAN-Phosphoserine275 def: "Protein CCNC_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:P24863] xref: UniProtKB:P24863 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001553 ! CCNC_HUMAN [Term] id: CCO:B0031304 name: CCNC_HUMAN-Phosphoserine279 def: "Protein CCNC_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:P24863] xref: UniProtKB:P24863 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001553 ! CCNC_HUMAN [Term] id: CCO:B0031305 name: CCNC_HUMAN-Phosphoserine281 def: "Protein CCNC_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:P24863] xref: UniProtKB:P24863 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001553 ! CCNC_HUMAN [Term] id: CCO:B0031306 name: CS025_HUMAN-Phosphotyrosine63 def: "Protein CS025_HUMAN with the residue 63 substituted with Phosphotyrosine" [UniProtKB:Q9UFG5] comment: By similarity xref: UniProtKB:Q9UFG5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006066 ! CS025_HUMAN [Term] id: CCO:B0031307 name: CTND1_HUMAN-Phosphotyrosine904 def: "Protein CTND1_HUMAN with the residue 904 substituted with Phosphotyrosine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0031308 name: CTRO_HUMAN-Phosphotyrosine1196 def: "Protein CTRO_HUMAN with the residue 1196 substituted with Phosphotyrosine" [UniProtKB:O14578] comment: By similarity xref: UniProtKB:O14578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001356 ! CTRO_HUMAN [Term] id: CCO:B0031309 name: CTRO_HUMAN-Phosphotyrosine1478 def: "Protein CTRO_HUMAN with the residue 1478 substituted with Phosphotyrosine" [UniProtKB:O14578] comment: By similarity xref: UniProtKB:O14578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001356 ! CTRO_HUMAN [Term] id: CCO:B0031310 name: DCTN2_HUMAN-Phosphotyrosine86 def: "Protein DCTN2_HUMAN with the residue 86 substituted with Phosphotyrosine" [UniProtKB:Q13561] comment: By similarity xref: UniProtKB:Q13561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005177 ! DCTN2_HUMAN [Term] id: CCO:B0031311 name: DLG1_HUMAN-Phosphotyrosine399 def: "Protein DLG1_HUMAN with the residue 399 substituted with Phosphotyrosine" [UniProtKB:Q12959] comment: By similarity xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0031312 name: DPYL1_HUMAN-Phosphotyrosine431 def: "Protein DPYL1_HUMAN with the residue 431 substituted with Phosphotyrosine" [UniProtKB:Q14194] comment: By similarity xref: UniProtKB:Q14194 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:B0031313 name: DPYL1_HUMAN-Phosphotyrosine504 def: "Protein DPYL1_HUMAN with the residue 504 substituted with Phosphotyrosine" [UniProtKB:Q14194] comment: By similarity xref: UniProtKB:Q14194 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000628 ! dihydropyrimidinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:B0031315 name: ENOG_HUMAN-Phosphotyrosine25 def: "Protein ENOG_HUMAN with the residue 25 substituted with Phosphotyrosine" [UniProtKB:P09104] comment: By similarity xref: UniProtKB:P09104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006270 ! ENOG_HUMAN [Term] id: CCO:B0031316 name: FAK2_HUMAN-Phosphotyrosine440 def: "Protein FAK2_HUMAN with the residue 440 substituted with Phosphotyrosine" [UniProtKB:Q14289] comment: By similarity xref: UniProtKB:Q14289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005846 ! FAK2_HUMAN [Term] id: CCO:B0031317 name: FGFR3_HUMAN-Phosphotyrosine647 def: "Protein FGFR3_HUMAN with the residue 647 substituted with Phosphotyrosine" [UniProtKB:P22607] comment: By similarity xref: UniProtKB:P22607 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001344 ! fibroblast growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:B0031318 name: FNBP1_HUMAN-Phosphoserine497 def: "Protein FNBP1_HUMAN with the residue 497 substituted with Phosphoserine" [UniProtKB:Q96RU3] comment: By similarity xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0031319 name: FNBP1_HUMAN-Phosphotyrosine500 def: "Protein FNBP1_HUMAN with the residue 500 substituted with Phosphotyrosine" [UniProtKB:Q96RU3] comment: By similarity xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0031320 name: FXR1_HUMAN-Phosphotyrosine68 def: "Protein FXR1_HUMAN with the residue 68 substituted with Phosphotyrosine" [UniProtKB:P51114] comment: By similarity xref: UniProtKB:P51114 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006140 ! FXR1_HUMAN [Term] id: CCO:B0031321 name: FYN_HUMAN-Phosphotyrosine185 def: "Protein FYN_HUMAN with the residue 185 substituted with Phosphotyrosine" [UniProtKB:P06241] comment: By similarity xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0031322 name: G3P_HUMAN-Phosphotyrosine314 def: "Protein G3P_HUMAN with the residue 314 substituted with Phosphotyrosine" [UniProtKB:P04406] comment: By similarity xref: UniProtKB:P04406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:B0031323 name: G3P_HUMAN-Phosphotyrosine320 def: "Protein G3P_HUMAN with the residue 320 substituted with Phosphotyrosine" [UniProtKB:P04406] comment: By similarity xref: UniProtKB:P04406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:B0031324 name: GAB2_HUMAN-Phosphoserine264 def: "Protein GAB2_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q9UQC2] comment: By similarity xref: UniProtKB:Q9UQC2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005924 ! GAB2_HUMAN [Term] id: CCO:B0031325 name: GAB2_HUMAN-Phosphothreonine265 def: "Protein GAB2_HUMAN with the residue 265 substituted with Phosphothreonine" [UniProtKB:Q9UQC2] comment: By similarity xref: UniProtKB:Q9UQC2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005924 ! GAB2_HUMAN [Term] id: CCO:B0031326 name: GAB2_HUMAN-Phosphotyrosine293 def: "Protein GAB2_HUMAN with the residue 293 substituted with Phosphotyrosine" [UniProtKB:Q9UQC2] comment: By similarity xref: UniProtKB:Q9UQC2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005924 ! GAB2_HUMAN [Term] id: CCO:B0031327 name: GIT1_HUMAN-Phosphotyrosine224 def: "Protein GIT1_HUMAN with the residue 224 substituted with Phosphotyrosine" [UniProtKB:Q9Y2X7] comment: By similarity xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0031328 name: GRLF1_HUMAN-Phosphotyrosine1087 def: "Protein GRLF1_HUMAN with the residue 1087 substituted with Phosphotyrosine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0031329 name: H4_HUMAN-Phosphotyrosine52 def: "Protein H4_HUMAN with the residue 52 substituted with Phosphotyrosine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0031330 name: H4_HUMAN-Phosphotyrosine89 def: "Protein H4_HUMAN with the residue 89 substituted with Phosphotyrosine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0031331 name: HS90A_HUMAN-Phosphotyrosine313 def: "Protein HS90A_HUMAN with the residue 313 substituted with Phosphotyrosine" [UniProtKB:P07900] comment: By similarity xref: UniProtKB:P07900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004355 ! nitric-oxide synthase regulator activity relationship: has_function CCO:F0004601 ! TPR domain binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:B0031332 name: HS90A_HUMAN-Phosphotyrosine492 def: "Protein HS90A_HUMAN with the residue 492 substituted with Phosphotyrosine" [UniProtKB:P07900] comment: By similarity xref: UniProtKB:P07900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:B0031333 name: HS90B_HUMAN-Phosphotyrosine305 def: "Protein HS90B_HUMAN with the residue 305 substituted with Phosphotyrosine" [UniProtKB:P08238] comment: By similarity xref: UniProtKB:P08238 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:B0031334 name: HSP7C_HUMAN-Phosphotyrosine41 def: "Protein HSP7C_HUMAN with the residue 41 substituted with Phosphotyrosine" [UniProtKB:P11142] xref: UniProtKB:P11142 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005696 ! ATPase activity, coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:B0031335 name: LIS1_HUMAN-Phosphotyrosine28 def: "Protein LIS1_HUMAN with the residue 28 substituted with Phosphotyrosine" [UniProtKB:P43034] comment: By similarity xref: UniProtKB:P43034 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001618 ! LIS1_HUMAN [Term] id: CCO:B0031336 name: LYN_HUMAN-Phosphotyrosine193 def: "Protein LYN_HUMAN with the residue 193 substituted with Phosphotyrosine" [UniProtKB:P07948] xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0031337 name: LYN_HUMAN-Phosphotyrosine194 def: "Protein LYN_HUMAN with the residue 194 substituted with Phosphotyrosine" [UniProtKB:P07948] xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0031338 name: M2OM_HUMAN-Phosphotyrosine102 def: "Protein M2OM_HUMAN with the residue 102 substituted with Phosphotyrosine" [UniProtKB:Q02978] comment: By similarity xref: UniProtKB:Q02978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006316 ! M2OM_HUMAN [Term] id: CCO:B0031339 name: M2OM_HUMAN-Phosphotyrosine202 def: "Protein M2OM_HUMAN with the residue 202 substituted with Phosphotyrosine" [UniProtKB:Q02978] comment: By similarity xref: UniProtKB:Q02978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006316 ! M2OM_HUMAN [Term] id: CCO:B0031341 name: MTSS1_HUMAN-Phosphotyrosine526 def: "Protein MTSS1_HUMAN with the residue 526 substituted with Phosphotyrosine" [UniProtKB:O43312] comment: By similarity xref: UniProtKB:O43312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0000324 ! actin monomer binding relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: transformation_of CCO:B0001390 ! MTSS1_HUMAN [Term] id: CCO:B0031342 name: MYO16_HUMAN-Phosphotyrosine1432 def: "Protein MYO16_HUMAN with the residue 1432 substituted with Phosphotyrosine" [UniProtKB:Q9Y6X6] comment: By similarity xref: UniProtKB:Q9Y6X6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0002267 ! MYO16_HUMAN [Term] id: CCO:B0031343 name: NDC80_HUMAN-Phosphoserine55 def: "Protein NDC80_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:O14777] xref: UniProtKB:O14777 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001360 ! NDC80_HUMAN [Term] id: CCO:B0031344 name: NDC80_HUMAN-Phosphoserine62 def: "Protein NDC80_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:O14777] xref: UniProtKB:O14777 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001360 ! NDC80_HUMAN [Term] id: CCO:B0031345 name: NDC80_HUMAN-Phosphoserine76 def: "Protein NDC80_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:O14777] xref: UniProtKB:O14777 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001360 ! NDC80_HUMAN [Term] id: CCO:B0031346 name: NDC80_HUMAN-Phosphoserine77 def: "Protein NDC80_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:O14777] xref: UniProtKB:O14777 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001360 ! NDC80_HUMAN [Term] id: CCO:B0031347 name: NDC80_HUMAN-Phosphoserine165 def: "Protein NDC80_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:O14777] comment: by NEK2; xref: UniProtKB:O14777 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0001360 ! NDC80_HUMAN [Term] id: CCO:B0031348 name: NEK2_HUMAN-Phosphothreonine170 def: "Protein NEK2_HUMAN with the residue 170 substituted with Phosphothreonine" [UniProtKB:P51955] comment: by autocatalysis; Probable xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031349 name: NEK2_HUMAN-Phosphoserine171 def: "Protein NEK2_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:P51955] comment: by autocatalysis; Probable xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031350 name: NEK2_HUMAN-Phosphothreonine179 def: "Protein NEK2_HUMAN with the residue 179 substituted with Phosphothreonine" [UniProtKB:P51955] comment: by autocatalysis; xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031351 name: NEK2_HUMAN-Phosphoserine241 def: "Protein NEK2_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:P51955] comment: by autocatalysis; xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031352 name: NEK2_HUMAN-Phosphoserine356 def: "Protein NEK2_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:P51955] xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031353 name: NEK2_HUMAN-Phosphoserine387 def: "Protein NEK2_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:P51955] xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031354 name: NEK2_HUMAN-Phosphoserine390 def: "Protein NEK2_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:P51955] xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031355 name: NEK2_HUMAN-Phosphoserine397 def: "Protein NEK2_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:P51955] xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031356 name: NEK2_HUMAN-Phosphoserine402 def: "Protein NEK2_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:P51955] xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031357 name: NEK2_HUMAN-Phosphoserine428 def: "Protein NEK2_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:P51955] xref: UniProtKB:P51955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:B0031358 name: NFL_HUMAN-Phosphotyrosine43 def: "Protein NFL_HUMAN with the residue 43 substituted with Phosphotyrosine" [UniProtKB:P07196] comment: By similarity xref: UniProtKB:P07196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:B0031359 name: NFL_HUMAN-Phosphotyrosine424 def: "Protein NFL_HUMAN with the residue 424 substituted with Phosphotyrosine" [UniProtKB:P07196] comment: By similarity xref: UniProtKB:P07196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:B0031360 name: NFL_HUMAN-Phosphotyrosine432 def: "Protein NFL_HUMAN with the residue 432 substituted with Phosphotyrosine" [UniProtKB:P07196] comment: By similarity xref: UniProtKB:P07196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:B0031361 name: NUCL_HUMAN-Phosphoserine206 def: "Protein NUCL_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:P19338] xref: UniProtKB:P19338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:B0031362 name: PABP1_HUMAN-Phosphotyrosine116 def: "Protein PABP1_HUMAN with the residue 116 substituted with Phosphotyrosine" [UniProtKB:P11940] comment: By similarity xref: UniProtKB:P11940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005854 ! PABP1_HUMAN [Term] id: CCO:B0031363 name: PHB_HUMAN-Phosphotyrosine249 def: "Protein PHB_HUMAN with the residue 249 substituted with Phosphotyrosine" [UniProtKB:P35232] comment: By similarity xref: UniProtKB:P35232 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001591 ! PHB_HUMAN [Term] id: CCO:B0031364 name: PLCG1_HUMAN-Phosphotyrosine379 def: "Protein PLCG1_HUMAN with the residue 379 substituted with Phosphotyrosine" [UniProtKB:P19174] comment: By similarity xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0031365 name: PLCG1_HUMAN-Phosphotyrosine481 def: "Protein PLCG1_HUMAN with the residue 481 substituted with Phosphotyrosine" [UniProtKB:P19174] comment: By similarity xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0031366 name: PLCG1_HUMAN-Phosphotyrosine506 def: "Protein PLCG1_HUMAN with the residue 506 substituted with Phosphotyrosine" [UniProtKB:P19174] comment: By similarity xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0031367 name: PLCG1_HUMAN-Phosphotyrosine977 def: "Protein PLCG1_HUMAN with the residue 977 substituted with Phosphotyrosine" [UniProtKB:P19174] xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0031368 name: PROF2_HUMAN-Phosphotyrosine99 def: "Protein PROF2_HUMAN with the residue 99 substituted with Phosphotyrosine" [UniProtKB:P35080] xref: UniProtKB:P35080 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:B0031369 name: PTN6_HUMAN-Phosphotyrosine377 def: "Protein PTN6_HUMAN with the residue 377 substituted with Phosphotyrosine" [UniProtKB:P29350] comment: By similarity xref: UniProtKB:P29350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000213 ! phosphotyrosine binding relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005608 ! PTN6_HUMAN [Term] id: CCO:B0031370 name: PTN6_HUMAN-Phosphotyrosine536 def: "Protein PTN6_HUMAN with the residue 536 substituted with Phosphotyrosine" [UniProtKB:P29350] xref: UniProtKB:P29350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005608 ! PTN6_HUMAN [Term] id: CCO:B0031371 name: RHOB_HUMAN-Phosphotyrosine154 def: "Protein RHOB_HUMAN with the residue 154 substituted with Phosphotyrosine" [UniProtKB:P62745] comment: By similarity xref: UniProtKB:P62745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001692 ! RHOB_HUMAN [Term] id: CCO:B0031372 name: RS24_HUMAN-Phosphotyrosine81 def: "Protein RS24_HUMAN with the residue 81 substituted with Phosphotyrosine" [UniProtKB:P62847] comment: By similarity xref: UniProtKB:P62847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005726 ! RS24_HUMAN [Term] id: CCO:B0031373 name: SEPT7_HUMAN-Phosphotyrosine30 def: "Protein SEPT7_HUMAN with the residue 30 substituted with Phosphotyrosine" [UniProtKB:Q16181] xref: UniProtKB:Q16181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001816 ! SEPT7_HUMAN [Term] id: CCO:B0031374 name: SET_HUMAN-Phosphotyrosine146 def: "Protein SET_HUMAN with the residue 146 substituted with Phosphotyrosine" [UniProtKB:Q01105] comment: By similarity xref: UniProtKB:Q01105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005519 ! SET_HUMAN [Term] id: CCO:B0031375 name: SPTB2_HUMAN-Phosphotyrosine1805 def: "Protein SPTB2_HUMAN with the residue 1805 substituted with Phosphotyrosine" [UniProtKB:Q01082] comment: By similarity xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0031376 name: SRC_HUMAN-Phosphotyrosine187 def: "Protein SRC_HUMAN with the residue 187 substituted with Phosphotyrosine" [UniProtKB:P12931] comment: By similarity xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0031377 name: TBA4A_HUMAN-Phosphotyrosine319 def: "Protein TBA4A_HUMAN with the residue 319 substituted with Phosphotyrosine" [UniProtKB:P68366] comment: By similarity xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0031378 name: TBB2B_HUMAN-Phosphotyrosine36 def: "Protein TBB2B_HUMAN with the residue 36 substituted with Phosphotyrosine" [UniProtKB:Q9BVA1] comment: By similarity xref: UniProtKB:Q9BVA1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0002101 ! TBB2B_HUMAN [Term] id: CCO:B0031379 name: TBB4_HUMAN-Phosphotyrosine36 def: "Protein TBB4_HUMAN with the residue 36 substituted with Phosphotyrosine" [UniProtKB:P04350] comment: By similarity xref: UniProtKB:P04350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006167 ! TBB4_HUMAN [Term] id: CCO:B0031380 name: TBB5_HUMAN-Phosphotyrosine340 def: "Protein TBB5_HUMAN with the residue 340 substituted with Phosphotyrosine" [UniProtKB:P07437] comment: By similarity xref: UniProtKB:P07437 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005727 ! TBB5_HUMAN [Term] id: CCO:B0031381 name: VDAC1_HUMAN-Phosphotyrosine67 def: "Protein VDAC1_HUMAN with the residue 67 substituted with Phosphotyrosine" [UniProtKB:P21796] xref: UniProtKB:P21796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005765 ! VDAC1_HUMAN [Term] id: CCO:B0031382 name: VDAC2_HUMAN-Phosphotyrosine206 def: "Protein VDAC2_HUMAN with the residue 206 substituted with Phosphotyrosine" [UniProtKB:P45880] comment: By similarity xref: UniProtKB:P45880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005777 ! VDAC2_HUMAN [Term] id: CCO:B0031383 name: VDAC3_HUMAN-Phosphotyrosine48 def: "Protein VDAC3_HUMAN with the residue 48 substituted with Phosphotyrosine" [UniProtKB:Q9Y277] comment: By similarity xref: UniProtKB:Q9Y277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005738 ! VDAC3_HUMAN [Term] id: CCO:B0031384 name: VIME_HUMAN-Phosphotyrosine53 def: "Protein VIME_HUMAN with the residue 53 substituted with Phosphotyrosine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0031385 name: YBOX1_HUMAN-Phosphoserine167 def: "Protein YBOX1_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:P67809] xref: UniProtKB:P67809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:B0031386 name: YES_HUMAN-Phosphotyrosine194 def: "Protein YES_HUMAN with the residue 194 substituted with Phosphotyrosine" [UniProtKB:P07947] comment: By similarity xref: UniProtKB:P07947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005465 ! YES_HUMAN [Term] id: CCO:B0031387 name: YES_HUMAN-Phosphotyrosine222 def: "Protein YES_HUMAN with the residue 222 substituted with Phosphotyrosine" [UniProtKB:P07947] xref: UniProtKB:P07947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005465 ! YES_HUMAN [Term] id: CCO:B0031407 name: PAIRB_HUMAN def: "Plasminogen activator inhibitor 1 RNA-binding protein" [UniProtKB:Q8NC51] synonym: "PAI-RBP1" EXACT [UniProtKB:Q8NC51] synonym: "PAI1 RNA-binding protein 1" EXACT [UniProtKB:Q8NC51] synonym: "SERPINE1 mRNA-binding protein 1" EXACT [UniProtKB:Q8NC51] xref: EMBL:AAD34050.1 xref: EMBL:AAH02488.1 xref: EMBL:AAH03049.1 xref: EMBL:AAH08045.1 xref: EMBL:AAH17449.1 xref: EMBL:AAH19273.1 xref: EMBL:AAH20555.1 xref: EMBL:AAH26916.1 xref: EMBL:AAK51130.1 xref: EMBL:BAC11324.1 xref: EMBL:CAB45718.1 xref: EMBL:CAG33664.1 xref: UniProtKB:Q8NC51 xref: UniProtKB:Q8WUH0 xref: UniProtKB:Q96SE2 xref: UniProtKB:Q9BTY3 xref: UniProtKB:Q9BUM4 xref: UniProtKB:Q9Y367 xref: UniProtKB:Q9Y4S3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007946 ! SERBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018183 ! cgi-cdh_3 physical interaction relationship: participates_in CCO:I0018184 ! cgi-cdh_3-2 physical interaction relationship: participates_in CCO:I0018186 ! cdh_3-cgi-1 physical interaction relationship: participates_in CCO:I0018493 ! cgi-cdh_3-1 physical interaction relationship: participates_in CCO:I0019360 ! cdh_3-cgi physical interaction relationship: participates_in CCO:P0002223 ! regulation of mRNA stability relationship: transforms_into CCO:B0035322 ! PAIRB_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0035323 ! PAIRB_HUMAN-Phosphothreonine61 relationship: transforms_into CCO:B0035324 ! PAIRB_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0035325 ! PAIRB_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0035326 ! PAIRB_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0035327 ! PAIRB_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0035328 ! PAIRB_HUMAN-Phosphothreonine232 relationship: transforms_into CCO:B0035329 ! PAIRB_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0035330 ! PAIRB_HUMAN-Phosphotyrosine244 relationship: transforms_into CCO:B0035331 ! PAIRB_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0035332 ! PAIRB_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0035333 ! PAIRB_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0035334 ! PAIRB_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0069062 ! PAIRB_HUMAN-Phosphothreonine255 relationship: transforms_into CCO:B0069063 ! PAIRB_HUMAN-Phosphoserine394 [Term] id: CCO:B0031499 name: GBP2_HUMAN def: "Interferon-induced guanylate-binding protein 2" [UniProtKB:P32456] synonym: "GBP-2" EXACT [UniProtKB:P32456] synonym: "GTP-binding protein 2" EXACT [UniProtKB:P32456] synonym: "Guanine nucleotide-binding protein 2" EXACT [UniProtKB:P32456] synonym: "HuGBP-2" EXACT [UniProtKB:P32456] xref: EMBL:AAA67323.1 xref: EMBL:CAD89925.1 xref: UniProtKB:P32456 xref: UniProtKB:Q86TB0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022268 ! GBP2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020037 ! hspe1-gbp2 physical interaction relationship: participates_in CCO:I0020122 ! ppp1r8-gbp2 physical interaction relationship: participates_in CCO:I0020166 ! serpinb9-gbp2 physical interaction relationship: participates_in CCO:I0020191 ! tfg-gbp2 physical interaction [Term] id: CCO:B0031540 name: APC2_HUMAN def: "Adenomatous polyposis coli protein 2" [UniProtKB:O95996] synonym: "Adenomatous polyposis coli protein-like" EXACT [UniProtKB:O95996] synonym: "APC-like" EXACT [UniProtKB:O95996] xref: EMBL:AAD28183.1 xref: EMBL:AAD29273.1 xref: EMBL:AAD29274.1 xref: EMBL:AAF01784.1 xref: EMBL:AAH32573.1 xref: EMBL:BAA34611.1 xref: EMBL:BAA75469.1 xref: EMBL:CAA10317.1 xref: EMBL:CAB61207.1 xref: EMBL:EAW69498.1 xref: UniProtKB:O95996 xref: UniProtKB:Q05BW4 xref: UniProtKB:Q9UBZ1 xref: UniProtKB:Q9UEM8 xref: UniProtKB:Q9UQJ8 xref: UniProtKB:Q9UQJ9 xref: UniProtKB:Q9Y632 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005985 ! APC2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000784 ! catenin complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0031563 name: NTKL_HUMAN def: "N-terminal kinase-like protein" [UniProtKB:Q96KG9] synonym: "SCY1-like protein 1" EXACT [UniProtKB:Q96KG9] synonym: "Telomerase regulation-associated protein" EXACT [UniProtKB:Q96KG9] synonym: "Telomerase transcriptional element-interacting factor" EXACT [UniProtKB:Q96KG9] synonym: "Teratoma-associated tyrosine kinase" EXACT [UniProtKB:Q96KG9] xref: EMBL:AAF81422.1 xref: EMBL:AAG09726.1 xref: EMBL:AAG17902.1 xref: EMBL:AAH09967.2 xref: EMBL:AAH69233.1 xref: EMBL:BAB55454.1 xref: EMBL:BAB55458.1 xref: EMBL:BAB55459.1 xref: EMBL:EAW74399.1 xref: UniProtKB:A6NJF1 xref: UniProtKB:Q96G50 xref: UniProtKB:Q96KG8 xref: UniProtKB:Q96KG9 xref: UniProtKB:Q96KH1 xref: UniProtKB:Q9HAW5 xref: UniProtKB:Q9HBL3 xref: UniProtKB:Q9NR53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007901 ! SCYL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035311 ! NTKL_HUMAN-Phosphoserine754 [Term] id: CCO:B0031593 name: ARC1B_HUMAN def: "Actin-related protein 2/3 complex subunit 1B" [UniProtKB:O15143] synonym: "Arp2/3 complex 41 kDa subunit" EXACT [UniProtKB:O15143] synonym: "p41-ARC" EXACT [UniProtKB:O15143] xref: EMBL:AAB64189.1 xref: EMBL:AAH02562.1 xref: EMBL:AAH02988.2 xref: EMBL:AAH07555.1 xref: UniProtKB:O15143 xref: UniProtKB:Q9BU00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011250 ! ARPC1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: transforms_into CCO:B0039321 ! ARC1B_HUMAN-Phosphoserine310 [Term] id: CCO:B0031598 name: ARC1A_HUMAN def: "Actin-related protein 2/3 complex subunit 1A" [UniProtKB:Q92747] synonym: "SOP2-like protein" EXACT [UniProtKB:Q92747] xref: EMBL:AAH39594.2 xref: EMBL:AAH47889.2 xref: EMBL:AAH54027.1 xref: EMBL:CAA70203.1 xref: UniProtKB:Q7Z5U8 xref: UniProtKB:Q86WU5 xref: UniProtKB:Q8IXQ0 xref: UniProtKB:Q92747 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011249 ! ARPC1A_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0031607 name: TA2R5_HUMAN def: "Taste receptor type 2 member 5" [UniProtKB:Q9NYW4] synonym: "T2R5" EXACT [UniProtKB:Q9NYW4] xref: EMBL:AAF43905.1 xref: EMBL:AAH69509.1 xref: EMBL:AAI01587.1 xref: EMBL:AAI01589.1 xref: EMBL:AAS02040.1 xref: EMBL:AAU21159.1 xref: UniProtKB:Q645W0 xref: UniProtKB:Q75MV7 xref: UniProtKB:Q9NYW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008259 ! TAS2R5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0031622 name: CDD_HUMAN def: "Cytidine deaminase" [UniProtKB:P32320] synonym: "Cytidine aminohydrolase" EXACT [UniProtKB:P32320] synonym: "EC 3.5.4.5" EXACT [UniProtKB:P32320] xref: EMBL:AAA57254.1 xref: EMBL:AAB24946.1 xref: EMBL:AAD15828.1 xref: EMBL:AAH54036.1 xref: EMBL:CAA04113.1 xref: EMBL:CAH73474.1 xref: UniProtKB:P32320 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007363 ! CDA_human relationship: has_function CCO:F0000246 ! nucleoside binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000597 ! cytidine deaminase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002656 ! negative regulation of nucleotide metabolic process [Term] id: CCO:B0031623 name: FX4L2_HUMAN def: "Forkhead box protein D4-like 2" [UniProtKB:Q6VB85] synonym: "FOXD4-like 2" EXACT [UniProtKB:Q6VB85] xref: EMBL:AAQ76879.1 xref: UniProtKB:Q6VB85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007561 ! FOXD4L2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0031624 name: FOXA1_HUMAN def: "Hepatocyte nuclear factor 3-alpha" [UniProtKB:P55317] synonym: "Forkhead box protein A1" EXACT [UniProtKB:P55317] synonym: "HNF-3-alpha" EXACT [UniProtKB:P55317] synonym: "HNF-3A" EXACT [UniProtKB:P55317] xref: EMBL:AAB06493.1 xref: EMBL:AAD51979.1 xref: EMBL:AAG40847.1 xref: EMBL:AAH33890.1 xref: UniProtKB:P55317 xref: UniProtKB:Q9H2A0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007532 ! FOXA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0034793 ! FOXA1_HUMAN-Phosphothreonine344 [Term] id: CCO:B0031625 name: FOXA3_HUMAN def: "Hepatocyte nuclear factor 3-gamma" [UniProtKB:P55318] synonym: "Fork head-related protein FKH H3" EXACT [UniProtKB:P55318] synonym: "Forkhead box protein A3" EXACT [UniProtKB:P55318] synonym: "HNF-3-gamma" EXACT [UniProtKB:P55318] synonym: "HNF-3G" EXACT [UniProtKB:P55318] xref: EMBL:AAA58477.1 xref: EMBL:AAD51980.1 xref: EMBL:AAH16024.1 xref: EMBL:AAP35366.1 xref: EMBL:ABX44664.1 xref: EMBL:BAD97193.1 xref: EMBL:EAW57394.1 xref: UniProtKB:A9LYI5 xref: UniProtKB:P55318 xref: UniProtKB:Q53F16 xref: UniProtKB:Q9UMW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007534 ! FOXA3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0031630 name: LIPA1_HUMAN def: "Liprin-alpha-1" [UniProtKB:Q13136] synonym: "LAR-interacting protein 1" EXACT [UniProtKB:Q13136] synonym: "LIP.1" EXACT [UniProtKB:Q13136] synonym: "Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1" EXACT [UniProtKB:Q13136] synonym: "PTPRF-interacting protein alpha-1" EXACT [UniProtKB:Q13136] xref: EMBL:AAC50172.1 xref: EMBL:AAC50173.1 xref: EMBL:AAH34046.1 xref: EMBL:BAA08353.1 xref: UniProtKB:A6NLE3 xref: UniProtKB:Q13135 xref: UniProtKB:Q13136 xref: UniProtKB:Q14567 xref: UniProtKB:Q8N4I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007780 ! PPFIA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015178 ! ppfia1-ppp2r5d physical interaction relationship: participates_in CCO:I0015424 ! ppfia1-tnnt1 physical interaction relationship: participates_in CCO:I0015505 ! mbip-ppfia1 physical interaction relationship: participates_in CCO:I0019429 ! ppfia1-ppp2r5d-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035100 ! LIPA1_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0035101 ! LIPA1_HUMAN-Phosphoserine242 relationship: transforms_into CCO:B0035102 ! LIPA1_HUMAN-Phosphoserine776 relationship: transforms_into CCO:B0052517 ! LIPA1_HUMAN-Phosphotyrosine684 relationship: transforms_into CCO:B0052518 ! LIPA1_HUMAN-Phosphoserine763 relationship: transforms_into CCO:B0067677 ! LIPA1_HUMAN-Phosphothreonine230 relationship: transforms_into CCO:B0067678 ! LIPA1_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0067679 ! LIPA1_HUMAN-Phosphoserine741 relationship: transforms_into CCO:B0067680 ! LIPA1_HUMAN-Phosphoserine745 [Term] id: CCO:B0031646 name: Q6S731_HUMAN def: "BSAP splice variant delta8" [UniProtKB:Q6S731] synonym: "Paired box gene 5 (B-cell lineage specific activator), isoform CRA_f" EXACT [UniProtKB:Q6S731] xref: EMBL:AAR27592.1 xref: EMBL:EAW58299.1 xref: UniProtKB:Q6S731 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005270 ! PAX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031650 name: Q6S729_HUMAN def: "BSAP splice variant delta78" [UniProtKB:Q6S729] synonym: "Paired box gene 5 (B-cell lineage specific activator), isoform CRA_d" EXACT [UniProtKB:Q6S729] xref: EMBL:AAR27594.1 xref: EMBL:EAW58297.1 xref: UniProtKB:Q6S729 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005270 ! PAX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031654 name: PAX6_HUMAN def: "Paired box protein Pax-6" [UniProtKB:P26367] synonym: "Aniridia type II protein" EXACT [UniProtKB:P26367] synonym: "Oculorhombin" EXACT [UniProtKB:P26367] xref: EMBL:AAA36416.1 xref: EMBL:AAA59962.1 xref: EMBL:AAA59963.1 xref: EMBL:AAH11953.1 xref: EMBL:AAK95849.1 xref: EMBL:CAE45868.1 xref: EMBL:CAG38087.1 xref: EMBL:CAG38363.1 xref: UniProtKB:P26367 xref: UniProtKB:Q6N006 xref: UniProtKB:Q99413 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019309 ! PAX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015328 ! ipo13-pax6 physical interaction relationship: participates_in CCO:I0019439 ! pax6-homer3-1 physical interaction relationship: participates_in CCO:I0019440 ! pax6-homer3-2 physical interaction relationship: participates_in CCO:I0019441 ! pax6-trim11-1 physical interaction relationship: participates_in CCO:I0019510 ! pax6-homer3-3 physical interaction relationship: participates_in CCO:I0019511 ! pax6-trim11-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002945 ! regulation of neurogenesis [Term] id: CCO:B0031655 name: Q6S732_HUMAN def: "BSAP splice variant delta7" [UniProtKB:Q6S732] synonym: "Paired box gene 5 (B-cell lineage specific activator), isoform CRA_b" EXACT [UniProtKB:Q6S732] xref: EMBL:AAR27591.1 xref: EMBL:EAW58295.1 xref: UniProtKB:Q6S732 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005270 ! PAX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031656 name: Q6S728_HUMAN def: "BSAP splice variant delta789" [UniProtKB:Q6S728] synonym: "Paired box gene 5 (B-cell lineage specific activator), isoform CRA_a" EXACT [UniProtKB:Q6S728] xref: EMBL:AAR27595.1 xref: EMBL:EAW58294.1 xref: UniProtKB:Q6S728 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005270 ! PAX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031660 name: Q6S730_HUMAN def: "BSAP splice variant delta9" [UniProtKB:Q6S730] synonym: "Paired box gene 5 (B-cell lineage specific activator), isoform CRA_c" EXACT [UniProtKB:Q6S730] xref: EMBL:AAR27593.1 xref: EMBL:EAW58296.1 xref: UniProtKB:Q6S730 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005270 ! PAX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031661 name: PAX2_HUMAN def: "Paired box protein Pax-2" [UniProtKB:Q02962] xref: EMBL:AAA36417.1 xref: EMBL:AAA60024.1 xref: EMBL:AAC41711.1 xref: EMBL:AAC63385.1 xref: UniProtKB:Q02962 xref: UniProtKB:Q15105 xref: UniProtKB:Q15110 xref: UniProtKB:Q15837 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019306 ! PAX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0002178 ! centriolar satellite relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031667 name: RSPO2_HUMAN def: "R-spondin-2 precursor" [UniProtKB:Q6UXX9] synonym: "hRspo2" EXACT [UniProtKB:Q6UXX9] synonym: "Roof plate-specific spondin-2" EXACT [UniProtKB:Q6UXX9] xref: EMBL:AAH27938.1 xref: EMBL:AAH36554.1 xref: EMBL:AAQ88533.1 xref: UniProtKB:Q4G0U4 xref: UniProtKB:Q6UXX9 xref: UniProtKB:Q8N6X6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019804 ! RSPO2_human relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0031669 name: RSPO1_HUMAN def: "R-spondin-1 precursor" [UniProtKB:Q2MKA7] synonym: "hRspo1" EXACT [UniProtKB:Q2MKA7] synonym: "Roof plate-specific spondin-1" EXACT [UniProtKB:Q2MKA7] xref: EMBL:AAI14967.1 xref: EMBL:ABA54597.1 xref: EMBL:ABC54570.1 xref: EMBL:BAC05263.1 xref: EMBL:CAI15785.1 xref: UniProtKB:Q14C72 xref: UniProtKB:Q2MKA7 xref: UniProtKB:Q5T0F2 xref: UniProtKB:Q8N7L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019803 ! RSPO1_human relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0031672 name: RSPO4_HUMAN def: "R-spondin-4 precursor" [UniProtKB:Q2I0M5] synonym: "hRspo4" EXACT [UniProtKB:Q2I0M5] synonym: "Roof plate-specific spondin-4" EXACT [UniProtKB:Q2I0M5] xref: EMBL:ABC75877.1 xref: EMBL:CAB65783.4 xref: UniProtKB:Q2I0M5 xref: UniProtKB:Q9UGB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019806 ! RSPO4_human relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0070250 ! RSPO4_HUMAN-Phosphotyrosine112 [Term] id: CCO:B0031673 name: RSPO3_HUMAN def: "R-spondin-3 precursor" [UniProtKB:Q9BXY4] synonym: "hPWTSR" EXACT [UniProtKB:Q9BXY4] synonym: "hRspo3" EXACT [UniProtKB:Q9BXY4] synonym: "Protein with TSP type-1 repeat" EXACT [UniProtKB:Q9BXY4] synonym: "Roof plate-specific spondin-3" EXACT [UniProtKB:Q9BXY4] synonym: "Thrombospondin type-1 domain-containing protein 2" EXACT [UniProtKB:Q9BXY4] xref: EMBL:AAH22367.1 xref: EMBL:AAK34947.1 xref: EMBL:BAB55051.1 xref: EMBL:CAH71124.1 xref: EMBL:CAH71125.1 xref: EMBL:CAI20141.1 xref: EMBL:CAI20142.1 xref: UniProtKB:Q5VTV4 xref: UniProtKB:Q96K87 xref: UniProtKB:Q9BXY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019805 ! RSPO3_human relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0031679 name: MBP_HUMAN def: "Myelin basic protein" [UniProtKB:P02686] synonym: "MBP" EXACT [UniProtKB:P02686] synonym: "Myelin A1 protein" EXACT [UniProtKB:P02686] synonym: "Myelin membrane encephalitogenic protein" EXACT [UniProtKB:P02686] xref: EMBL:AAA59559.1 xref: EMBL:AAA59560.1 xref: EMBL:AAA59561.1 xref: EMBL:AAA59562.1 xref: EMBL:AAA59563.1 xref: EMBL:AAA59564.1 xref: EMBL:AAA72008.1 xref: EMBL:AAA72009.1 xref: EMBL:AAA72010.1 xref: EMBL:AAA72011.1 xref: EMBL:AAC41944.1 xref: EMBL:AAH08749.3 xref: EMBL:AAH65248.1 xref: EMBL:AAH80654.1 xref: EMBL:AAI01772.1 xref: EMBL:AAI01774.1 xref: EMBL:BAD92223.1 xref: EMBL:CAA35179.1 xref: EMBL:CAG38771.1 xref: EMBL:CAG46717.1 xref: EMBL:CAH10359.1 xref: UniProtKB:A4FU54 xref: UniProtKB:A6NI84 xref: UniProtKB:P02686 xref: UniProtKB:Q15337 xref: UniProtKB:Q15338 xref: UniProtKB:Q15339 xref: UniProtKB:Q15340 xref: UniProtKB:Q59GX3 xref: UniProtKB:Q65ZS4 xref: UniProtKB:Q6AI64 xref: UniProtKB:Q6FH37 xref: UniProtKB:Q6FI04 xref: UniProtKB:Q6PK23 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007816 ! MBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0018912 ! aptx-mbp physical interaction relationship: participates_in CCO:I0018977 ! atxn1-mbp physical interaction relationship: transforms_into CCO:B0035166 ! MBP_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0035167 ! MBP_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0035168 ! MBP_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0035169 ! MBP_HUMAN-Citrulline159 relationship: transforms_into CCO:B0035170 ! MBP_HUMAN-Citrulline165 relationship: transforms_into CCO:B0035171 ! MBP_HUMAN-Phosphothreonine169 relationship: transforms_into CCO:B0035172 ! MBP_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0035173 ! MBP_HUMAN-Phosphotyrosine203 relationship: transforms_into CCO:B0035174 ! MBP_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0035175 ! MBP_HUMAN-Phosphothreonine229 relationship: transforms_into CCO:B0035176 ! MBP_HUMAN-Phosphothreonine232 relationship: transforms_into CCO:B0035177 ! MBP_HUMAN-Deamidated glutamine237 relationship: transforms_into CCO:B0035178 ! MBP_HUMAN-Omega-N-methylarginine241 relationship: transforms_into CCO:B0035179 ! MBP_HUMAN-dimethylarginine241 relationship: transforms_into CCO:B0035180 ! MBP_HUMAN-Phosphoserine249 relationship: transforms_into CCO:B0035181 ! MBP_HUMAN-Citrulline256 relationship: transforms_into CCO:B0035182 ! MBP_HUMAN-Citrulline264 relationship: transforms_into CCO:B0035183 ! MBP_HUMAN-Deamidated glutamine281 relationship: transforms_into CCO:B0035184 ! MBP_HUMAN-Citrulline293 relationship: transforms_into CCO:B0035185 ! MBP_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0035186 ! MBP_HUMAN-Phosphoserine299 relationship: transforms_into CCO:B0035187 ! MBP_HUMAN-Citrulline304 [Term] id: CCO:B0031707 name: CATK_HUMAN def: "Cathepsin K precursor" [UniProtKB:P43235] synonym: "Cathepsin O" EXACT [UniProtKB:P43235] synonym: "Cathepsin O2" EXACT [UniProtKB:P43235] synonym: "Cathepsin X" EXACT [UniProtKB:P43235] synonym: "EC 3.4.22.38" EXACT [UniProtKB:P43235] xref: EMBL:AAA65233.1 xref: EMBL:AAA95998.1 xref: EMBL:AAB35521.1 xref: EMBL:AAH16058.1 xref: EMBL:CAA57649.1 xref: UniProtKB:P43235 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007340 ! CTSK_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000671 ! cathepsin K activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:I0019996 ! fgfr3-ctsk physical interaction [Term] id: CCO:B0031753 name: Q5T270_HUMAN def: "TBC1D13 protein" [UniProtKB:Q5T270] synonym: "cDNA FLJ76589, highly similar to TBC1 domain family member 13" EXACT [UniProtKB:Q5T270] synonym: "TBC1 domain family, member 13" EXACT [UniProtKB:Q5T270] synonym: "TBC1 domain family, member 13, isoform CRA_a" EXACT [UniProtKB:Q5T270] xref: EMBL:AAI32818.1 xref: EMBL:BAF82466.1 xref: EMBL:CAI15411.1 xref: EMBL:EAW87832.1 xref: UniProtKB:Q5T270 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008274 ! TBC1D13_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0031754 name: TBC13_HUMAN def: "TBC1 domain family member 13" [UniProtKB:Q9NVG8] xref: EMBL:BAA91784.1 xref: EMBL:CAI15410.1 xref: EMBL:EAW87833.1 xref: UniProtKB:Q5T271 xref: UniProtKB:Q9NVG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008274 ! TBC1D13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0035761 ! TBC13_HUMAN-Phosphothreonine96 relationship: transforms_into CCO:B0035762 ! TBC13_HUMAN-Phosphoserine108 [Term] id: CCO:B0031760 name: SFRS5_HUMAN def: "Splicing factor, arginine/serine-rich 5" [UniProtKB:Q13243] synonym: "Delayed-early protein HRS" EXACT [UniProtKB:Q13243] synonym: "Pre-mRNA-splicing factor SRP40" EXACT [UniProtKB:Q13243] xref: EMBL:AAA93070.1 xref: EMBL:AAA93074.1 xref: EMBL:AAB60405.1 xref: EMBL:AAC39543.1 xref: EMBL:AAH18823.1 xref: EMBL:AAH40209.1 xref: EMBL:AAP35752.1 xref: UniProtKB:O14797 xref: UniProtKB:Q13243 xref: UniProtKB:Q16662 xref: UniProtKB:Q49AD6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022648 ! SFRS5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020341 ! igsf2-sfrs5 physical interaction relationship: transforms_into CCO:B0070429 ! SFRS5_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0070430 ! SFRS5_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0070431 ! SFRS5_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0070432 ! SFRS5_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0070433 ! SFRS5_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0070434 ! SFRS5_HUMAN-Phosphoserine250 relationship: transforms_into CCO:B0070435 ! SFRS5_HUMAN-Phosphoserine253 [Term] id: CCO:B0031787 name: NOE2_HUMAN def: "Noelin-2 precursor" [UniProtKB:O95897] synonym: "Olfactomedin-2" EXACT [UniProtKB:O95897] xref: EMBL:AAD20056.1 xref: EMBL:AAH11361.1 xref: EMBL:DAA01550.1 xref: UniProtKB:O95897 xref: UniProtKB:Q6IMJ3 xref: UniProtKB:Q96FC2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007889 ! OLFM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020613 ! olfm2-gnb5 physical interaction relationship: participates_in CCO:I0020614 ! olfm2-robo2 physical interaction relationship: participates_in CCO:I0020615 ! olfm2-sui1 physical interaction relationship: participates_in CCO:I0020637 ! rab11b-olfm2 physical interaction [Term] id: CCO:B0031800 name: OLFL3_HUMAN def: "Olfactomedin-like protein 3 precursor" [UniProtKB:Q9NRN5] synonym: "HNOEL-iso" EXACT [UniProtKB:Q9NRN5] synonym: "hOLF44" EXACT [UniProtKB:Q9NRN5] xref: EMBL:AAF86881.1 xref: EMBL:AAH09920.1 xref: EMBL:AAQ89313.1 xref: EMBL:AAR88262.1 xref: EMBL:BAC11564.1 xref: EMBL:BAC11644.1 xref: EMBL:BAC11687.1 xref: EMBL:BAD96191.1 xref: EMBL:BAD96941.1 xref: EMBL:CAI22797.1 xref: EMBL:CAI22798.1 xref: UniProtKB:Q53FR1 xref: UniProtKB:Q53HV9 xref: UniProtKB:Q5SQL6 xref: UniProtKB:Q69AX9 xref: UniProtKB:Q8NBJ2 xref: UniProtKB:Q9NRN5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007916 ! OLFML3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0020028 ! olfml3-setdb1 physical interaction [Term] id: CCO:B0031813 name: IFNG_HUMAN def: "Interferon gamma precursor" [UniProtKB:P01579] synonym: "IFN-gamma" EXACT [UniProtKB:P01579] synonym: "Immune interferon" EXACT [UniProtKB:P01579] xref: EMBL:AAB59534.1 xref: EMBL:AAH70256.1 xref: EMBL:AAK53058.1 xref: EMBL:CAA23804.1 xref: EMBL:CAA26022.1 xref: EMBL:CAA31639.1 xref: UniProtKB:P01579 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007662 ! IFNG_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001435 ! interferon-gamma receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0008966 ! ifng-ifngr1-1 direct interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: participates_in CCO:P0001480 ! negative regulation of myelination relationship: participates_in CCO:P0001971 ! positive regulation of smooth muscle cell apoptosis relationship: participates_in CCO:P0002272 ! positive regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002276 ! positive regulation of interleukin-12 biosynthetic process relationship: participates_in CCO:P0002351 ! positive regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002815 ! positive regulation of isotype switching to IgG isotypes relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation relationship: transforms_into CCO:B0034870 ! IFNG_HUMAN-Pyrrolidone carboxylic acid24 [Term] id: CCO:B0031823 name: MYO3B_HUMAN def: "Myosin-IIIB" [UniProtKB:Q8WXR4] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8WXR4] xref: EMBL:AAL57233.1 xref: EMBL:AAO13799.1 xref: EMBL:AAO13800.1 xref: EMBL:AAO13801.1 xref: EMBL:AAO13802.1 xref: EMBL:AAO13803.1 xref: EMBL:AAY24159.1 xref: EMBL:AAY24324.1 xref: EMBL:BAB71011.1 xref: UniProtKB:Q53QE1 xref: UniProtKB:Q53T08 xref: UniProtKB:Q8IX64 xref: UniProtKB:Q8IX65 xref: UniProtKB:Q8IX66 xref: UniProtKB:Q8IX67 xref: UniProtKB:Q8IX68 xref: UniProtKB:Q8WXR4 xref: UniProtKB:Q96N94 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022422 ! MYO3B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000788 ! myosin complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0031878 name: VWF_HUMAN def: "von Willebrand factor precursor" [UniProtKB:P04275] synonym: "vWF" EXACT [UniProtKB:P04275] xref: EMBL:AAA61293.1 xref: EMBL:AAA61294.1 xref: EMBL:AAA61295.1 xref: EMBL:AAA65940.1 xref: EMBL:AAB39987.1 xref: EMBL:AAB59458.1 xref: EMBL:AAB59512.1 xref: EMBL:CAA26503.1 xref: EMBL:CAA27765.1 xref: EMBL:CAA27972.1 xref: EMBL:CAA29985.1 xref: UniProtKB:P04275 xref: UniProtKB:Q99806 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015080 ! VWF_human relationship: has_function CCO:F0000251 ! glycoprotein binding relationship: has_function CCO:F0000256 ! protease binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_function CCO:F0004198 ! immunoglobulin binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001109 ! extracellular matrix relationship: located_in CCO:C0001128 ! platelet alpha granule relationship: located_in CCO:C0001515 ! Weibel-Palade body relationship: participates_in CCO:I0015985 ! adamts13-vwf-7 protein cleavage relationship: participates_in CCO:I0019180 ! adamts13-vwf-1 protein cleavage relationship: participates_in CCO:I0019305 ! adamts13-vwf protein cleavage relationship: participates_in CCO:I0019307 ! adamts13-vwf-8 protein cleavage relationship: participates_in CCO:I0019308 ! adamts13-vwf-9 protein cleavage [Term] id: CCO:B0031883 name: Q9UMI9_HUMAN def: "Mucin-like protein" [UniProtKB:Q9UMI9] xref: EMBL:AAA59861.1 xref: UniProtKB:Q9UMI9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022864 ! MLP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction [Term] id: CCO:B0031899 name: NARFL_HUMAN def: "Nuclear prelamin A recognition factor-like protein" [UniProtKB:Q9H6Q4] synonym: "IOP1" EXACT [UniProtKB:Q9H6Q4] synonym: "Iron-only hydrogenase-like protein 1" EXACT [UniProtKB:Q9H6Q4] synonym: "Protein related to Narf" EXACT [UniProtKB:Q9H6Q4] xref: EMBL:AAH30248.1 xref: EMBL:AAI29941.1 xref: EMBL:AAK61251.1 xref: EMBL:AAM98737.1 xref: EMBL:BAB15199.1 xref: EMBL:BAB15261.1 xref: EMBL:BAD96725.1 xref: EMBL:CAM26480.1 xref: UniProtKB:A1L385 xref: UniProtKB:Q53GC6 xref: UniProtKB:Q96S10 xref: UniProtKB:Q9H6J8 xref: UniProtKB:Q9H6Q4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007864 ! NARFL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0031918 name: CX020_HUMAN def: "Uncharacterized protein CXorf20" [UniProtKB:Q8NDZ0] xref: EMBL:AAH37301.1 xref: EMBL:CAI42219.1 xref: UniProtKB:Q5JXE5 xref: UniProtKB:Q8NDZ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022162 ! CXorf20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017556 ! cxorf20-atxn1 physical interaction [Term] id: CCO:B0031949 name: FINC_HUMAN def: "Fibronectin precursor" [UniProtKB:P02751] synonym: "CIG" EXACT [UniProtKB:P02751] synonym: "Cold-insoluble globulin" EXACT [UniProtKB:P02751] synonym: "FN" EXACT [UniProtKB:P02751] xref: EMBL:AAA52461.1 xref: EMBL:AAA52462.1 xref: EMBL:AAA52463.1 xref: EMBL:AAA52465.1 xref: EMBL:AAA53376.1 xref: EMBL:AAA58483.1 xref: EMBL:AAD00014.1 xref: EMBL:AAD00015.1 xref: EMBL:AAD00017.1 xref: EMBL:AAD00018.1 xref: EMBL:AAD00019.1 xref: EMBL:AAD04751.1 xref: EMBL:AAD09448.1 xref: EMBL:AAD09449.1 xref: EMBL:AAD09450.1 xref: EMBL:AAG30571.1 xref: EMBL:AAI17177.1 xref: EMBL:AAX76513.1 xref: EMBL:BAD52437.1 xref: EMBL:BAD93077.1 xref: EMBL:CAA26536.1 xref: EMBL:CAB52436.1 xref: EMBL:CAB52437.1 xref: EMBL:CAC20427.1 xref: EMBL:CAC86914.1 xref: EMBL:CAC86915.1 xref: EMBL:CAC86916.1 xref: EMBL:CAD59389.1 xref: EMBL:CAD91166.1 xref: EMBL:CAD97791.1 xref: EMBL:CAD97964.1 xref: EMBL:CAD97965.1 xref: EMBL:CAE45714.1 xref: EMBL:CAE45847.1 xref: EMBL:CAE45932.1 xref: EMBL:CAH18136.1 xref: EMBL:CAH18171.1 xref: EMBL:CAH18172.1 xref: UniProtKB:O95609 xref: UniProtKB:O95610 xref: UniProtKB:P02751 xref: UniProtKB:Q14312 xref: UniProtKB:Q14325 xref: UniProtKB:Q14326 xref: UniProtKB:Q17RV7 xref: UniProtKB:Q585T2 xref: UniProtKB:Q59EH1 xref: UniProtKB:Q60FE4 xref: UniProtKB:Q68DP8 xref: UniProtKB:Q68DP9 xref: UniProtKB:Q68DT4 xref: UniProtKB:Q6LDP6 xref: UniProtKB:Q6MZU5 xref: UniProtKB:Q6N025 xref: UniProtKB:Q6N0A6 xref: UniProtKB:Q86T27 xref: UniProtKB:Q8IVI8 xref: UniProtKB:Q96KP7 xref: UniProtKB:Q96KP8 xref: UniProtKB:Q96KP9 xref: UniProtKB:Q9H1B8 xref: UniProtKB:Q9HAP3 xref: UniProtKB:Q9UMK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007531 ! FN1_human relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0034789 ! FINC_HUMAN-Pyrrolidone carboxylic acid32 relationship: transforms_into CCO:B0034790 ! FINC_HUMAN-Sulfotyrosine876 relationship: transforms_into CCO:B0034791 ! FINC_HUMAN-Sulfotyrosine881 relationship: transforms_into CCO:B0034792 ! FINC_HUMAN-Phosphoserine2384 [Term] id: CCO:B0031984 name: RBL2A_HUMAN def: "Rab-like protein 2A" [UniProtKB:Q9UBK7] xref: EMBL:AAD51377.1 xref: EMBL:AAD51378.1 xref: EMBL:CAB81644.1 xref: EMBL:CAB81645.1 xref: UniProtKB:Q9NU37 xref: UniProtKB:Q9UBK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008061 ! RABL2A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0031985 name: Q8WUI7_HUMAN def: "RABL2B protein" [UniProtKB:Q8WUI7] xref: EMBL:AAH20495.1 xref: UniProtKB:Q8WUI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0031988 name: RBL2B_HUMAN def: "Rab-like protein 2B" [UniProtKB:Q9UNT1] xref: EMBL:AAD51379.1 xref: EMBL:AAH14879.1 xref: EMBL:AAH24281.1 xref: UniProtKB:Q96C33 xref: UniProtKB:Q9UNT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008062 ! RABL2B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0032066 name: A8W2K5_HUMAN def: "MutL-like 1 protein" [UniProtKB:A8W2K5] xref: EMBL:ABW69167.1 xref: UniProtKB:A8W2K5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005100 ! MLH1_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0032072 name: CNOT1_HUMAN def: "CCR4-NOT transcription complex subunit 1" [UniProtKB:A5YKK6] synonym: "CCR4-associated factor 1" EXACT [UniProtKB:A5YKK6] synonym: "hNOT1" EXACT [UniProtKB:A5YKK6] synonym: "Negative regulator of transcription subunit 1 homolog" EXACT [UniProtKB:A5YKK6] synonym: "NOT1H" EXACT [UniProtKB:A5YKK6] xref: EMBL:AAF14861.1 xref: EMBL:AAH00779.2 xref: EMBL:AAH24317.1 xref: EMBL:AAH40523.1 xref: EMBL:ABQ66268.1 xref: EMBL:BAA76851.2 xref: EMBL:CAB55960.1 xref: EMBL:CAD97851.1 xref: EMBL:CAH18093.1 xref: UniProtKB:A5YKK6 xref: UniProtKB:Q68DX7 xref: UniProtKB:Q7Z3K2 xref: UniProtKB:Q8IWB8 xref: UniProtKB:Q8TB53 xref: UniProtKB:Q9BVZ6 xref: UniProtKB:Q9UFR8 xref: UniProtKB:Q9UI27 xref: UniProtKB:Q9Y2L0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007403 ! CNOT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0043234 ! CNOT1_HUMAN-Phosphotyrosine1933 [Term] id: CCO:B0032137 name: PKHA6_HUMAN def: "Pleckstrin homology domain-containing family A member 6" [UniProtKB:Q9Y2H5] synonym: "PEPP-3" EXACT [UniProtKB:Q9Y2H5] synonym: "Phosphoinositol 3-phosphate-binding protein 3" EXACT [UniProtKB:Q9Y2H5] xref: EMBL:AAI52476.1 xref: EMBL:BAA76813.2 xref: EMBL:CAH71228.1 xref: UniProtKB:A7MD51 xref: UniProtKB:Q5VTI6 xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007978 ! PLEKHA6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0035369 ! PKHA6_HUMAN-Phosphoserine472 relationship: transforms_into CCO:B0035370 ! PKHA6_HUMAN-Phosphoserine476 relationship: transforms_into CCO:B0035371 ! PKHA6_HUMAN-Phosphotyrosine492 relationship: transforms_into CCO:B0035372 ! PKHA6_HUMAN-Phosphothreonine744 relationship: transforms_into CCO:B0035373 ! PKHA6_HUMAN-Phosphoserine777 relationship: transforms_into CCO:B0035374 ! PKHA6_HUMAN-Phosphoserine848 relationship: transforms_into CCO:B0035375 ! PKHA6_HUMAN-Phosphoserine854 relationship: transforms_into CCO:B0069339 ! PKHA6_HUMAN-Phosphoserine867 [Term] id: CCO:B0032261 name: TEAD3_HUMAN def: "Transcriptional enhancer factor TEF-5" [UniProtKB:Q99594] synonym: "DTEF-1" EXACT [UniProtKB:Q99594] synonym: "TEA domain family member 3" EXACT [UniProtKB:Q99594] synonym: "TEAD-3" EXACT [UniProtKB:Q99594] xref: EMBL:AAH27877.1 xref: EMBL:AAH91488.2 xref: EMBL:CAA64213.2 xref: UniProtKB:O95910 xref: UniProtKB:Q5BJG7 xref: UniProtKB:Q8N6Y4 xref: UniProtKB:Q99594 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020225 ! TEAD3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0015276 ! ctbp2-tead3 physical interaction relationship: participates_in CCO:I0015668 ! tead3-wwtr1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0032263 name: Q7Z6U9_HUMAN def: "TEA domain family member 3" [UniProtKB:Q7Z6U9] xref: EMBL:CAD92501.1 xref: UniProtKB:Q7Z6U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020225 ! TEAD3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032264 name: Q96BK2_HUMAN def: "TEA domain family member 4" [UniProtKB:Q96BK2] xref: EMBL:AAH15497.2 xref: UniProtKB:Q96BK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021251 ! TEAD4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015361 ! q96bk2-wwtr1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032266 name: Q8NEV5_HUMAN def: "Related transcription enhancer factor 1B" [UniProtKB:Q8NEV5] xref: EMBL:AAM89497.1 xref: UniProtKB:Q8NEV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032267 name: Q7Z6U7_HUMAN def: "TEA domain family member 3" [UniProtKB:Q7Z6U7] xref: EMBL:CAD92503.1 xref: UniProtKB:Q7Z6U7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020225 ! TEAD3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032268 name: TEAD2_HUMAN def: "Transcriptional enhancer factor TEF-4" [UniProtKB:Q15562] synonym: "TEA domain family member 2" EXACT [UniProtKB:Q15562] synonym: "TEAD-2" EXACT [UniProtKB:Q15562] xref: EMBL:AAH07556.1 xref: EMBL:CAA64214.1 xref: UniProtKB:Q15562 xref: UniProtKB:Q96IG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020224 ! TEAD2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0032269 name: Q6MZR9_HUMAN def: "Putative uncharacterized protein DKFZp686G19178" [UniProtKB:Q6MZR9] synonym: "TEA domain family member 4, isoform CRA_a" EXACT [UniProtKB:Q6MZR9] xref: EMBL:CAE45959.1 xref: EMBL:EAW88872.1 xref: UniProtKB:Q6MZR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021184 ! DKFZp686G19178_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032270 name: Q8NA25_HUMAN def: "TEAD2 protein" [UniProtKB:Q8NA25] synonym: "cDNA FLJ35917 fis, clone TESTI2010409, highly similar to TRANSCRIPTIONAL ENHANCER FACTOR TEF-4" EXACT [UniProtKB:Q8NA25] synonym: "cDNA FLJ77886, highly similar to Homo sapiens TEA domain family member 2, mRNA" EXACT [UniProtKB:Q8NA25] synonym: "TEA domain family member 2, isoform CRA_a" EXACT [UniProtKB:Q8NA25] xref: EMBL:AAH51301.1 xref: EMBL:BAC04104.1 xref: EMBL:BAF83425.1 xref: EMBL:EAW52469.1 xref: UniProtKB:Q8NA25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020224 ! TEAD2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032274 name: A4FUP2_HUMAN def: "TEAD1 protein" [UniProtKB:A4FUP2] xref: EMBL:AAI15399.1 xref: UniProtKB:A4FUP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020223 ! TEAD1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032276 name: Q59EF3_HUMAN def: "TEA domain family member 1 variant" [UniProtKB:Q59EF3] xref: EMBL:BAD93095.1 xref: UniProtKB:Q59EF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032277 name: TEAD1_HUMAN def: "Transcriptional enhancer factor TEF-1" [UniProtKB:P28347] synonym: "NTEF-1" EXACT [UniProtKB:P28347] synonym: "Protein GT-IIC" EXACT [UniProtKB:P28347] synonym: "TEA domain family member 1" EXACT [UniProtKB:P28347] synonym: "TEAD-1" EXACT [UniProtKB:P28347] synonym: "Transcription factor 13" EXACT [UniProtKB:P28347] xref: EMBL:AAB00791.1 xref: UniProtKB:P28347 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020223 ! TEAD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071314 ! TEAD1_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0071315 ! TEAD1_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0071316 ! TEAD1_HUMAN-Phosphoserine11 [Term] id: CCO:B0032298 name: I17RA_HUMAN def: "Interleukin-17 receptor A precursor" [UniProtKB:Q96F46] synonym: "CD217 antigen" EXACT [UniProtKB:Q96F46] synonym: "CDw217" EXACT [UniProtKB:Q96F46] synonym: "IL-17 receptor" EXACT [UniProtKB:Q96F46] xref: EMBL:AAB99730.1 xref: EMBL:AAH11624.1 xref: UniProtKB:O43844 xref: UniProtKB:Q96F46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007638 ! IL17RA_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0004413 ! interleukin-17 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0032300 name: FRDA_HUMAN def: "Frataxin, mitochondrial precursor" [UniProtKB:Q16595] synonym: "Friedreich ataxia protein" EXACT [UniProtKB:Q16595] synonym: "Fxn" EXACT [UniProtKB:Q16595] xref: EMBL:AAA98508.1 xref: EMBL:AAA98509.1 xref: EMBL:AAA98510.1 xref: EMBL:AAB84047.1 xref: EMBL:AAD00734.1 xref: EMBL:AAH23633.1 xref: EMBL:AAH48097.1 xref: EMBL:CAA74077.1 xref: EMBL:CAH71829.1 xref: UniProtKB:O15545 xref: UniProtKB:O95656 xref: UniProtKB:Q15294 xref: UniProtKB:Q16595 xref: UniProtKB:Q5VZ01 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022261 ! FXN_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001599 ! iron ion transmembrane transporter activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0019146 ! fxn-actn1 physical interaction relationship: participates_in CCO:I0019147 ! fxn-prkcabp physical interaction [Term] id: CCO:B0032323 name: BT3L3_HUMAN def: "Transcription factor BTF3 homolog 3" [UniProtKB:Q13892] synonym: "Basic transcription factor 3-like 3" EXACT [UniProtKB:Q13892] xref: EMBL:AAA58401.1 xref: UniProtKB:Q13892 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017185 ! BTF3L3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064008 ! BT3L3_HUMAN-Phosphoserine77 [Term] id: CCO:B0032333 name: BTF3_HUMAN def: "Transcription factor BTF3" [UniProtKB:P20290] synonym: "RNA polymerase B transcription factor 3" EXACT [UniProtKB:P20290] xref: EMBL:AAA58398.1 xref: EMBL:AAH08062.1 xref: EMBL:AAP35784.1 xref: EMBL:BAB93458.1 xref: EMBL:CAA37375.1 xref: EMBL:CAA37376.1 xref: EMBL:CAA52200.1 xref: UniProtKB:P20290 xref: UniProtKB:Q13893 xref: UniProtKB:Q76M56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017187 ! BTF3_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064011 ! BTF3_HUMAN-Phosphoserine30 [Term] id: CCO:B0032335 name: EID3_HUMAN def: "EP300-interacting inhibitor of differentiation 3" [UniProtKB:Q8N140] synonym: "E1A-like inhibitor of differentiation 3" EXACT [UniProtKB:Q8N140] synonym: "EID-1-like inhibitor of differentiation 3" EXACT [UniProtKB:Q8N140] synonym: "EID-3" EXACT [UniProtKB:Q8N140] xref: EMBL:AAH27612.1 xref: EMBL:BAC05385.1 xref: EMBL:EAW97747.1 xref: UniProtKB:Q8N140 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007486 ! EID3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015124 ! appbp2-eid3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032342 name: K2C74_HUMAN def: "Keratin, type II cytoskeletal 74" [UniProtKB:Q7RTS7] synonym: "Cytokeratin-74" EXACT [UniProtKB:Q7RTS7] synonym: "Keratin-5c" EXACT [UniProtKB:Q7RTS7] synonym: "Keratin-74" EXACT [UniProtKB:Q7RTS7] synonym: "Type II inner root sheath-specific keratin-K6irs4" EXACT [UniProtKB:Q7RTS7] synonym: "Type II keratin-37" EXACT [UniProtKB:Q7RTS7] xref: EMBL:CAD48514.1 xref: EMBL:DAA00404.1 xref: EMBL:EAW96637.1 xref: UniProtKB:Q7RTS7 xref: UniProtKB:Q86Y45 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007704 ! KRT74_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction [Term] id: CCO:B0032345 name: Q5Y190_HUMAN def: "Anchor protein" [UniProtKB:Q5Y190] xref: EMBL:AAU94938.1 xref: UniProtKB:Q5Y190 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008688 ! RESDA1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001811 ! secondary active sulfate transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0032349 name: CELR2_HUMAN def: "Cadherin EGF LAG seven-pass G-type receptor 2 precursor" [UniProtKB:Q9HCU4] synonym: "Epidermal growth factor-like 2" EXACT [UniProtKB:Q9HCU4] synonym: "Flamingo 1" EXACT [UniProtKB:Q9HCU4] synonym: "Multiple epidermal growth factor-like domains 3" EXACT [UniProtKB:Q9HCU4] xref: EMBL:AAG00080.1 xref: EMBL:BAA13407.2 xref: EMBL:BAC06168.1 xref: EMBL:CAI13170.1 xref: UniProtKB:Q5T2Y7 xref: UniProtKB:Q92566 xref: UniProtKB:Q9HCU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007379 ! CELSR2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020528 ! celsr2-klf6 physical interaction relationship: participates_in CCO:I0020529 ! celsr2-gars physical interaction relationship: participates_in CCO:I0020530 ! celsr2-phf10 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001237 ! regulation of cell-cell adhesion relationship: participates_in CCO:P0001644 ! regulation of gene-specific transcription relationship: transforms_into CCO:B0034642 ! CELR2_HUMAN-3-hydroxyasparagine1591 relationship: transforms_into CCO:B0034643 ! CELR2_HUMAN-3-hydroxyasparagine1810 [Term] id: CCO:B0032351 name: A6NLC3_HUMAN xref: UniProtKB:A6NLC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032352 name: Q7Z2R1_HUMAN def: "ZNF254 protein" [UniProtKB:Q7Z2R1] synonym: "HCG19985, isoform CRA_b" EXACT [UniProtKB:Q7Z2R1] xref: EMBL:AAH56243.1 xref: EMBL:EAW84961.1 xref: UniProtKB:Q7Z2R1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020680 ! ZNF254_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032357 name: Q6NVI0_HUMAN def: "ZNF85 protein" [UniProtKB:Q6NVI0] xref: EMBL:AAH68066.1 xref: UniProtKB:Q6NVI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020991 ! ZNF85_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032358 name: Q7Z7K8_HUMAN def: "ZNF718 protein" [UniProtKB:Q7Z7K8] xref: EMBL:AAH52600.1 xref: UniProtKB:Q7Z7K8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020917 ! ZNF718_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032362 name: Q6ZNF3_HUMAN def: "cDNA FLJ16156 fis, clone BRAWH2006207, moderately similar to Zinc finger protein 91" [UniProtKB:Q6ZNF3] synonym: "Zinc finger protein 680, isoform CRA_f" EXACT [UniProtKB:Q6ZNF3] xref: EMBL:BAD18422.1 xref: EMBL:EAW77971.1 xref: UniProtKB:Q6ZNF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011762 ! ZNF680_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032363 name: ZN738_HUMAN def: "Protein ZNF738" [UniProtKB:Q8NE65] xref: EMBL:AAH34499.1 xref: EMBL:BAF83691.1 xref: EMBL:BAF83882.1 xref: UniProtKB:A8K4N7 xref: UniProtKB:Q8NE65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020921 ! ZNF738_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032364 name: Q96QM1_HUMAN def: "Zinc finger protein 626" [UniProtKB:Q96QM1] synonym: "Zinc finger protein 626, isoform CRA_b" EXACT [UniProtKB:Q96QM1] xref: EMBL:AAH07116.1 xref: EMBL:AAI07804.1 xref: EMBL:EAW84879.1 xref: UniProtKB:Q96QM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011761 ! ZNF626_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032365 name: A6NEM4_HUMAN def: "Putative uncharacterized protein ZNF738" [UniProtKB:A6NEM4] xref: UniProtKB:A6NEM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020921 ! ZNF738_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032368 name: Q75LP1_HUMAN def: "Putative uncharacterized protein MGC12518" [UniProtKB:Q75LP1] xref: EMBL:AAQ93371.1 xref: UniProtKB:Q75LP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021208 ! MGC12518_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032369 name: Q6NS90_HUMAN def: "ZNF93 protein" [UniProtKB:Q6NS90] xref: EMBL:AAH70372.1 xref: EMBL:AAI07582.1 xref: UniProtKB:Q6NS90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020995 ! ZNF93_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032380 name: NF2L1_HUMAN def: "Nuclear factor erythroid 2-related factor 1" [UniProtKB:Q14494] synonym: "Locus control region-factor 1" EXACT [UniProtKB:Q14494] synonym: "NF-E2-related factor 1" EXACT [UniProtKB:Q14494] synonym: "NFE2-related factor 1" EXACT [UniProtKB:Q14494] synonym: "Nuclear factor, erythroid derived 2, like 1" EXACT [UniProtKB:Q14494] synonym: "Transcription factor 11" EXACT [UniProtKB:Q14494] synonym: "Transcription factor HBZ17" EXACT [UniProtKB:Q14494] synonym: "Transcription factor LCR-F1" EXACT [UniProtKB:Q14494] xref: EMBL:AAA20466.1 xref: EMBL:AAH10623.1 xref: EMBL:CAA54555.1 xref: UniProtKB:Q12877 xref: UniProtKB:Q14494 xref: UniProtKB:Q96FN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007875 ! NFE2L1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068601 ! NF2L1_HUMAN-Phosphotyrosine645 [Term] id: CCO:B0032381 name: Q8NF22_HUMAN def: "FLJ00380 protein" [UniProtKB:Q8NF22] xref: EMBL:BAC03440.1 xref: UniProtKB:Q8NF22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008879 ! FLJ00380_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032388 name: TCPQ_HUMAN def: "T-complex protein 1 subunit theta" [UniProtKB:P50990] synonym: "CCT-theta" EXACT [UniProtKB:P50990] synonym: "Renal carcinoma antigen NY-REN-15" EXACT [UniProtKB:P50990] synonym: "TCP-1-theta" EXACT [UniProtKB:P50990] xref: EMBL:AAH72001.1 xref: EMBL:AAH95470.1 xref: EMBL:BAA02792.2 xref: EMBL:BAA07652.1 xref: EMBL:CAA85520.1 xref: EMBL:CAB90433.1 xref: UniProtKB:A6NN54 xref: UniProtKB:P50990 xref: UniProtKB:Q4VBP8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008280 ! CCT8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016593 ! map3k1-cct8 physical interaction relationship: participates_in CCO:I0016666 ! map3k3-cct8 physical interaction relationship: participates_in CCO:I0016958 ! tbk1-cct8 physical interaction relationship: transforms_into CCO:B0035763 ! TCPQ_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035764 ! TCPQ_HUMAN-N6-acetyllysine20 relationship: transforms_into CCO:B0035765 ! TCPQ_HUMAN-Phosphothreonine227 relationship: transforms_into CCO:B0035766 ! TCPQ_HUMAN-Phosphothreonine232 relationship: transforms_into CCO:B0035767 ! TCPQ_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0035768 ! TCPQ_HUMAN-Phosphotyrosine505 relationship: transforms_into CCO:B0071291 ! TCPQ_HUMAN-Phosphoserine23 [Term] id: CCO:B0032391 name: MTND_HUMAN def: "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase" [UniProtKB:Q9BV57] synonym: "Aci-reductone dioxygenase" EXACT [UniProtKB:Q9BV57] synonym: "ARD" EXACT [UniProtKB:Q9BV57] synonym: "EC 1.13.-.-" EXACT [UniProtKB:Q9BV57] synonym: "Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1" EXACT [UniProtKB:Q9BV57] synonym: "MTCBP-1" EXACT [UniProtKB:Q9BV57] synonym: "SIPL" EXACT [UniProtKB:Q9BV57] synonym: "Submergence-induced protein 2 homolog" EXACT [UniProtKB:Q9BV57] xref: EMBL:AAH01467.1 xref: EMBL:AAL25800.1 xref: EMBL:AAP97173.1 xref: EMBL:AAX82038.1 xref: EMBL:AAY24022.1 xref: EMBL:BAA91901.1 xref: EMBL:BAC86996.1 xref: EMBL:BAD10866.1 xref: EMBL:BAD38646.1 xref: EMBL:BAD96187.1 xref: UniProtKB:Q53HW3 xref: UniProtKB:Q53QD3 xref: UniProtKB:Q57YV7 xref: UniProtKB:Q68CK2 xref: UniProtKB:Q6ZSF7 xref: UniProtKB:Q7Z512 xref: UniProtKB:Q96P85 xref: UniProtKB:Q9BV57 xref: UniProtKB:Q9NV57 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007843 ! ADI1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003042 ! nickel ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008070 ! dioxygenase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015991 ! mmp14-adi1-2 physical interaction relationship: participates_in CCO:I0018242 ! mmp14-adi1-1 physical interaction relationship: participates_in CCO:I0018389 ! mmp14-adi1-3 physical interaction relationship: participates_in CCO:I0019461 ! mmp14-adi1-4 colocalization [Term] id: CCO:B0032438 name: FBX8_HUMAN def: "F-box only protein 8" [UniProtKB:Q9NRD0] synonym: "F-box/SEC7 protein FBS" EXACT [UniProtKB:Q9NRD0] xref: EMBL:AAF04517.1 xref: EMBL:AAF67154.1 xref: EMBL:AAF86868.1 xref: EMBL:AAH14679.1 xref: EMBL:AAQ89083.1 xref: UniProtKB:Q6UWN4 xref: UniProtKB:Q9NRD0 xref: UniProtKB:Q9NRP5 xref: UniProtKB:Q9UKC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007527 ! FBXO8_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0032439 name: Q8IWE1_HUMAN def: "FBXO8 protein" [UniProtKB:Q8IWE1] xref: EMBL:AAH40456.1 xref: UniProtKB:Q8IWE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007527 ! FBXO8_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0032440 name: Q8IXA8_HUMAN def: "MSTP051" [UniProtKB:Q8IXA8] xref: EMBL:AAO06951.1 xref: UniProtKB:Q8IXA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008862 ! MST051_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0032462 name: CIRBP_HUMAN def: "Cold-inducible RNA-binding protein" [UniProtKB:Q14011] synonym: "A18 hnRNP" EXACT [UniProtKB:Q14011] synonym: "Glycine-rich RNA-binding protein CIRP" EXACT [UniProtKB:Q14011] xref: EMBL:AAC04895.1 xref: EMBL:AAC51787.1 xref: EMBL:AAH00403.1 xref: EMBL:AAH00901.1 xref: EMBL:BAA11212.1 xref: UniProtKB:Q14011 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007392 ! CIRBP_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019073 ! atxn1-cirbp physical interaction [Term] id: CCO:B0032483 name: ME3L1_HUMAN def: "Putative homeobox protein Meis3-like 1" [UniProtKB:A6NDR6] xref: UniProtKB:A6NDR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022394 ! MEIS3P1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032489 name: MEIS1_HUMAN def: "Homeobox protein Meis1" [UniProtKB:O00470] xref: EMBL:AAC51642.1 xref: EMBL:AAH43503.1 xref: UniProtKB:A8MV50 xref: UniProtKB:O00470 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007819 ! MEIS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032495 name: Q4G0U8_HUMAN def: "MEIS1 protein" [UniProtKB:Q4G0U8] synonym: "Meis1, myeloid ecotropic viral integration site 1 homolog (Mouse), isoform CRA_b" EXACT [UniProtKB:Q4G0U8] xref: EMBL:AAH36511.1 xref: EMBL:EAW99893.1 xref: UniProtKB:Q4G0U8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007819 ! MEIS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032498 name: A8MWD5_HUMAN def: "Putative uncharacterized protein MEIS2" [UniProtKB:A8MWD5] xref: UniProtKB:A8MWD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007820 ! MEIS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032499 name: MEIS2_HUMAN def: "Homeobox protein Meis2" [UniProtKB:O14770] synonym: "Meis1-related protein 1" EXACT [UniProtKB:O14770] xref: EMBL:AAB70270.1 xref: EMBL:AAF81638.1 xref: EMBL:AAF81639.1 xref: EMBL:AAF81640.1 xref: EMBL:AAF81641.1 xref: EMBL:AAF81642.1 xref: EMBL:AAH50431.1 xref: UniProtKB:O14770 xref: UniProtKB:Q96KI4 xref: UniProtKB:Q96KI5 xref: UniProtKB:Q9NRS1 xref: UniProtKB:Q9NRS2 xref: UniProtKB:Q9NRS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007820 ! MEIS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032501 name: MEIS3_HUMAN def: "Homeobox protein Meis3" [UniProtKB:Q99687] synonym: "Meis1-related protein 2" EXACT [UniProtKB:Q99687] xref: EMBL:AAB19195.1 xref: EMBL:AAH25404.1 xref: EMBL:AAH69251.1 xref: EMBL:CAB95771.1 xref: EMBL:CAH18472.1 xref: UniProtKB:Q6NT73 xref: UniProtKB:Q8TC66 xref: UniProtKB:Q99687 xref: UniProtKB:Q9NPW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007821 ! MEIS3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032504 name: ME3L2_HUMAN def: "Putative homeobox protein Meis3-like 2" [UniProtKB:A8K0S8] xref: EMBL:BAF82332.1 xref: UniProtKB:A8K0S8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022395 ! MEIS3P2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032508 name: Q96DI2_HUMAN def: "Meis homeobox 2" [UniProtKB:Q96DI2] synonym: "Meis1, myeloid ecotropic viral integration site 1 homolog 2 (Mouse), isoform CRA_j" EXACT [UniProtKB:Q96DI2] synonym: "Putative uncharacterized protein MEIS2" EXACT [UniProtKB:Q96DI2] xref: EMBL:AAH01516.1 xref: EMBL:AAH01844.3 xref: EMBL:AAH07202.1 xref: EMBL:EAW92354.1 xref: UniProtKB:A6NJI5 xref: UniProtKB:Q96DI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007820 ! MEIS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032516 name: A8MUV4_HUMAN def: "Putative uncharacterized protein FOXP2" [UniProtKB:A8MUV4] xref: UniProtKB:A8MUV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011396 ! FOXP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032520 name: LRRF1_HUMAN def: "Leucine-rich repeat flightless-interacting protein 1" [UniProtKB:Q32MZ4] synonym: "GC-binding factor 2" EXACT [UniProtKB:Q32MZ4] synonym: "LRR FLII-interacting protein 1" EXACT [UniProtKB:Q32MZ4] synonym: "TAR RNA-interacting protein" EXACT [UniProtKB:Q32MZ4] xref: EMBL:AAC32037.1 xref: EMBL:AAH01385.1 xref: EMBL:AAI08914.1 xref: EMBL:AAI08915.1 xref: EMBL:AAY14672.1 xref: EMBL:CAA11076.1 xref: UniProtKB:O75766 xref: UniProtKB:O75799 xref: UniProtKB:Q32MZ4 xref: UniProtKB:Q32MZ5 xref: UniProtKB:Q53T49 xref: UniProtKB:Q6PKG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007801 ! LRRFIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0035133 ! LRRF1_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0035134 ! LRRF1_HUMAN-Phosphothreonine123 relationship: transforms_into CCO:B0035135 ! LRRF1_HUMAN-Phosphothreonine295 relationship: transforms_into CCO:B0035136 ! LRRF1_HUMAN-Phosphoserine521 relationship: transforms_into CCO:B0035137 ! LRRF1_HUMAN-Phosphoserine714 relationship: transforms_into CCO:B0035138 ! LRRF1_HUMAN-Phosphoserine733 relationship: transforms_into CCO:B0067779 ! LRRF1_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0067780 ! LRRF1_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0067781 ! LRRF1_HUMAN-Phosphoserine581 relationship: transforms_into CCO:B0067782 ! LRRF1_HUMAN-Phosphoserine618 relationship: transforms_into CCO:B0067783 ! LRRF1_HUMAN-Phosphothreonine676 [Term] id: CCO:B0032521 name: LRRF2_HUMAN def: "Leucine-rich repeat flightless-interacting protein 2" [UniProtKB:Q9Y608] synonym: "LRR FLII-interacting protein 2" EXACT [UniProtKB:Q9Y608] xref: EMBL:AAD41257.1 xref: EMBL:AAH53668.1 xref: EMBL:BAA91035.1 xref: EMBL:CAH18481.1 xref: UniProtKB:Q68CV3 xref: UniProtKB:Q9NXH5 xref: UniProtKB:Q9Y608 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007802 ! LRRFIP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0035139 ! LRRF2_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0035140 ! LRRF2_HUMAN-Phosphothreonine331 relationship: transforms_into CCO:B0035141 ! LRRF2_HUMAN-Phosphoserine333 [Term] id: CCO:B0032527 name: NKX28_HUMAN def: "Homeobox protein Nkx-2.8" [UniProtKB:O15522] synonym: "Homeobox protein NK-2 homolog H" EXACT [UniProtKB:O15522] xref: EMBL:AAC71081.1 xref: EMBL:AAC71082.1 xref: EMBL:AAH41090.1 xref: EMBL:BAG36314.1 xref: UniProtKB:O15522 xref: UniProtKB:Q8IUT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018799 ! NKX2-8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032530 name: Q7KZF6_HUMAN def: "Thyroid transcription factor 1" [UniProtKB:Q7KZF6] synonym: "Thyroid transcription factor 1, isoform CRA_c" EXACT [UniProtKB:Q7KZF6] xref: EMBL:AAP88775.1 xref: EMBL:EAW65858.1 xref: UniProtKB:Q7KZF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021211 ! TITF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032532 name: Q5VZV8_HUMAN xref: UniProtKB:Q5VZV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0032537 name: SP16H_HUMAN def: "FACT complex subunit SPT16" [UniProtKB:Q9Y5B9] synonym: "Chromatin-specific transcription elongation factor 140 kDa subunit" EXACT [UniProtKB:Q9Y5B9] synonym: "Facilitates chromatin transcription complex subunit SPT16" EXACT [UniProtKB:Q9Y5B9] synonym: "FACT 140 kDa subunit" EXACT [UniProtKB:Q9Y5B9] synonym: "FACTp140" EXACT [UniProtKB:Q9Y5B9] synonym: "hSPT16" EXACT [UniProtKB:Q9Y5B9] xref: EMBL:AAD43978.1 xref: EMBL:AAF28231.1 xref: EMBL:AAH00565.1 xref: EMBL:AAH14046.1 xref: EMBL:AAH64561.1 xref: EMBL:AAH73849.1 xref: UniProtKB:Q6GMT8 xref: UniProtKB:Q6P2F1 xref: UniProtKB:Q6PJM1 xref: UniProtKB:Q9NRX0 xref: UniProtKB:Q9Y5B9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008210 ! SUPT16H_human relationship: has_function CCO:F0001753 ! positive transcription elongation factor activity relationship: has_function CCO:F0001785 ! metalloexopeptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035675 ! SP16H_HUMAN-Phosphoserine979 relationship: transforms_into CCO:B0035676 ! SP16H_HUMAN-Phosphoserine982 relationship: transforms_into CCO:B0035677 ! SP16H_HUMAN-Phosphoserine986 relationship: transforms_into CCO:B0043380 ! SP16H_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0070774 ! SP16H_HUMAN-Phosphoserine508 relationship: transforms_into CCO:B0070775 ! SP16H_HUMAN-Phosphoserine650 relationship: transforms_into CCO:B0070776 ! SP16H_HUMAN-Phosphoserine1015 [Term] id: CCO:B0032548 name: RAB8A_HUMAN def: "Ras-related protein Rab-8A" [UniProtKB:P61006] synonym: "Oncogene c-mel" EXACT [UniProtKB:P61006] xref: EMBL:AAB19681.1 xref: EMBL:AAH02977.1 xref: EMBL:AAM21091.1 xref: EMBL:AAP35848.1 xref: EMBL:CAA40065.1 xref: EMBL:CAG38820.1 xref: EMBL:CAG47070.1 xref: EMBL:EAW84526.1 xref: UniProtKB:P24407 xref: UniProtKB:P61006 xref: UniProtKB:Q6FHV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008047 ! RAB8A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001281 ! nonmotile primary cilium relationship: participates_in CCO:I0020429 ! rab8a-bat3 physical interaction relationship: participates_in CCO:I0020632 ! pqbp1-rab8a physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0035497 ! RAB8A_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0035498 ! RAB8A_HUMAN-Phosphoserine185 relationship: transforms_into CCO:B0069697 ! RAB8A_HUMAN-Phosphothreonine192 [Term] id: CCO:B0032549 name: RAB10_HUMAN def: "Ras-related protein Rab-10" [UniProtKB:P61026] xref: EMBL:AAD43034.1 xref: EMBL:AAG13413.1 xref: EMBL:AAH00896.1 xref: EMBL:AAM21093.1 xref: EMBL:AAP97147.1 xref: EMBL:BAB14474.1 xref: EMBL:CAB66585.1 xref: EMBL:CAG33584.1 xref: UniProtKB:O88386 xref: UniProtKB:P61026 xref: UniProtKB:Q6IA52 xref: UniProtKB:Q9D7X6 xref: UniProtKB:Q9H0T3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008042 ! RAB10_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0020605 ! sept9-rab10 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0032550 name: RAB8B_HUMAN def: "Ras-related protein Rab-8B" [UniProtKB:Q92930] xref: EMBL:AAC51199.1 xref: EMBL:AAH20654.1 xref: EMBL:BAA92249.1 xref: UniProtKB:Q92930 xref: UniProtKB:Q9P293 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008048 ! RAB8B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0032555 name: RAB13_HUMAN def: "Ras-related protein Rab-13" [UniProtKB:P51153] synonym: "Cell growth-inhibiting gene 4 protein" EXACT [UniProtKB:P51153] xref: EMBL:AAH00799.1 xref: EMBL:AAH09227.2 xref: EMBL:AAH73168.2 xref: EMBL:AAM21096.1 xref: EMBL:AAS00485.1 xref: EMBL:AAV38506.1 xref: EMBL:AAV38507.1 xref: EMBL:CAA53266.1 xref: EMBL:CAI14031.1 xref: UniProtKB:P51153 xref: UniProtKB:Q5U0A6 xref: UniProtKB:Q6GPG6 xref: UniProtKB:Q96GU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008043 ! RAB13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069665 ! RAB13_HUMAN-Phosphoserine178 [Term] id: CCO:B0032556 name: Q504R6_HUMAN def: "RAB13 protein" [UniProtKB:Q504R6] xref: EMBL:AAH94846.1 xref: UniProtKB:Q504R6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008043 ! RAB13_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0032571 name: HOP2_HUMAN def: "Homologous-pairing protein 2 homolog" [UniProtKB:Q9P2W1] synonym: "Nuclear receptor coactivator GT198" EXACT [UniProtKB:Q9P2W1] synonym: "Proteasome 26S ATPase subunit 3-interacting protein" EXACT [UniProtKB:Q9P2W1] synonym: "PSMC3-interacting protein" EXACT [UniProtKB:Q9P2W1] synonym: "Tat-binding protein 1-interacting protein" EXACT [UniProtKB:Q9P2W1] synonym: "TBP-1-interacting protein" EXACT [UniProtKB:Q9P2W1] xref: EMBL:AAC41915.1 xref: EMBL:AAH08792.1 xref: EMBL:AAL33609.1 xref: EMBL:BAA92872.1 xref: UniProtKB:Q14458 xref: UniProtKB:Q8WXG2 xref: UniProtKB:Q96HA2 xref: UniProtKB:Q9P2W1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006425 ! PSMC3IP_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000117 ! meiosis relationship: transforms_into CCO:B0032849 ! HOP2_HUMAN-Phosphoserine29 [Term] id: CCO:B0032592 name: ARP5_HUMAN def: "Actin-related protein 5" [UniProtKB:Q9H9F9] synonym: "hARP5" EXACT [UniProtKB:Q9H9F9] synonym: "Sarcoma antigen NY-SAR-16" EXACT [UniProtKB:Q9H9F9] xref: EMBL:AAH01324.1 xref: EMBL:AAH06162.1 xref: EMBL:AAH38402.1 xref: EMBL:AAO65164.1 xref: EMBL:BAB14270.1 xref: EMBL:CAD37358.1 xref: UniProtKB:Q86WF7 xref: UniProtKB:Q8IUY5 xref: UniProtKB:Q8N724 xref: UniProtKB:Q9BRN0 xref: UniProtKB:Q9BVB7 xref: UniProtKB:Q9H9F9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007267 ! ACTR5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032607 name: DNMT1_HUMAN def: "DNA (cytosine-5)-methyltransferase 1" [UniProtKB:P26358] synonym: "CXXC-type zinc finger protein 9" EXACT [UniProtKB:P26358] synonym: "DNA methyltransferase HsaI" EXACT [UniProtKB:P26358] synonym: "DNA MTase HsaI" EXACT [UniProtKB:P26358] synonym: "Dnmt1" EXACT [UniProtKB:P26358] synonym: "EC 2.1.1.37" EXACT [UniProtKB:P26358] synonym: "M.HsaI" EXACT [UniProtKB:P26358] synonym: "MCMT" EXACT [UniProtKB:P26358] xref: EMBL:AAD51619.1 xref: EMBL:AAD54507.1 xref: EMBL:AAF23609.1 xref: EMBL:CAA45219.1 xref: UniProtKB:P26358 xref: UniProtKB:Q9UHG5 xref: UniProtKB:Q9ULA2 xref: UniProtKB:Q9UMZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007467 ! DNMT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017520 ! ezh2-dnmt1 physical interaction relationship: participates_in CCO:I0017732 ! dnmt1-ezh2-2 physical interaction relationship: participates_in CCO:I0019291 ! dnmt1-ezh2 physical interaction relationship: participates_in CCO:I0019294 ! dnmt1-ezh2-1 physical interaction relationship: participates_in CCO:I0020295 ! dnmt1-rfp physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000646 ! DNA methylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001125 ! gene silencing relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0034711 ! DNMT1_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0034712 ! DNMT1_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0034713 ! DNMT1_HUMAN-Phosphoserine509 relationship: transforms_into CCO:B0034714 ! DNMT1_HUMAN-Phosphoserine714 relationship: transforms_into CCO:B0034715 ! DNMT1_HUMAN-Phosphoserine954 relationship: transforms_into CCO:B0034716 ! DNMT1_HUMAN-Phosphoserine1105 relationship: transforms_into CCO:B0034717 ! DNMT1_HUMAN-N6-acetyllysine1113 relationship: transforms_into CCO:B0034718 ! DNMT1_HUMAN-N6-acetyllysine1115 relationship: transforms_into CCO:B0034719 ! DNMT1_HUMAN-N6-acetyllysine1117 relationship: transforms_into CCO:B0064817 ! DNMT1_HUMAN-Phosphoserine732 relationship: transforms_into CCO:B0064818 ! DNMT1_HUMAN-Phosphotyrosine969 [Term] id: CCO:B0032651 name: PSMD6_HUMAN def: "26S proteasome non-ATPase regulatory subunit 6" [UniProtKB:Q15008] synonym: "26S proteasome regulatory subunit S10" EXACT [UniProtKB:Q15008] synonym: "Breast cancer-associated protein SGA-113M" EXACT [UniProtKB:Q15008] synonym: "p42A" EXACT [UniProtKB:Q15008] synonym: "Phosphonoformate immuno-associated protein 4" EXACT [UniProtKB:Q15008] synonym: "Proteasome regulatory particle subunit p44S10" EXACT [UniProtKB:Q15008] xref: EMBL:AAF65540.1 xref: EMBL:AAH00630.1 xref: EMBL:AAH00904.1 xref: EMBL:AAH12369.1 xref: EMBL:AAQ09946.1 xref: EMBL:AAS68366.1 xref: EMBL:BAA03497.1 xref: UniProtKB:Q15008 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008034 ! PSMD6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008712 ! traf6-psmd6 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0032700 name: TGS1_HUMAN def: "Trimethylguanosine synthase homolog" [UniProtKB:Q96RS0] synonym: "CLL-associated antigen KW-2" EXACT [UniProtKB:Q96RS0] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q96RS0] synonym: "Hepatocellular carcinoma-associated antigen 137" EXACT [UniProtKB:Q96RS0] synonym: "Nuclear receptor coactivator 6-interacting protein" EXACT [UniProtKB:Q96RS0] synonym: "PIMT" EXACT [UniProtKB:Q96RS0] synonym: "PIPMT" EXACT [UniProtKB:Q96RS0] synonym: "PRIP-interacting protein with methyltransferase motif" EXACT [UniProtKB:Q96RS0] xref: EMBL:AAH11999.1 xref: EMBL:AAK27730.1 xref: EMBL:AAK83025.1 xref: EMBL:AAL99922.1 xref: EMBL:AAT02709.1 xref: EMBL:BAB15516.1 xref: UniProtKB:A6NJQ5 xref: UniProtKB:Q5GH23 xref: UniProtKB:Q8TDG9 xref: UniProtKB:Q96QU3 xref: UniProtKB:Q96RS0 xref: UniProtKB:Q9H5V3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008287 ! TGS1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019135 ! coil-ncoa6ip physical interaction relationship: participates_in CCO:I0019144 ! coil-ncoa6ip-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071377 ! TGS1_HUMAN-Phosphoserine55 relationship: transforms_into CCO:B0071378 ! TGS1_HUMAN-Phosphothreonine60 relationship: transforms_into CCO:B0071379 ! TGS1_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0071380 ! TGS1_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0071381 ! TGS1_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0071382 ! TGS1_HUMAN-Phosphoserine438 [Term] id: CCO:B0032721 name: BDNF_HUMAN def: "Brain-derived neurotrophic factor precursor" [UniProtKB:P23560] synonym: "Abrineurin" EXACT [UniProtKB:P23560] synonym: "BDNF" EXACT [UniProtKB:P23560] xref: EMBL:AAA51820.1 xref: EMBL:AAA69805.2 xref: EMBL:AAA96140.1 xref: EMBL:AAG47514.1 xref: EMBL:AAH29795.1 xref: EMBL:AAK92487.1 xref: EMBL:CAA42761.1 xref: EMBL:CAA62632.1 xref: UniProtKB:P23560 xref: UniProtKB:Q9BYY7 xref: UniProtKB:Q9UC24 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007302 ! BDNF_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0017264 ! bdnf-ntf3-1 direct interaction [Term] id: CCO:B0032797 name: ACHB4_HUMAN def: "Neuronal acetylcholine receptor subunit beta-4 precursor" [UniProtKB:P30926] xref: EMBL:AAA92123.1 xref: EMBL:AAB40117.1 xref: EMBL:AAH96080.1 xref: EMBL:AAH96082.1 xref: EMBL:AAL02062.1 xref: EMBL:AAL57840.1 xref: EMBL:CAA48336.1 xref: EMBL:CAA69693.1 xref: EMBL:CAC34819.1 xref: UniProtKB:P30926 xref: UniProtKB:Q16607 xref: UniProtKB:Q4VBA5 xref: UniProtKB:Q8WXC8 xref: UniProtKB:Q9BQR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016896 ! CHRNB4_human relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002749 ! regulation of neurotransmitter secretion [Term] id: CCO:B0032798 name: ACHA6_HUMAN def: "Neuronal acetylcholine receptor subunit alpha-6 precursor" [UniProtKB:Q15825] xref: EMBL:AAB40113.1 xref: EMBL:AAH14456.1 xref: EMBL:BAC06855.1 xref: EMBL:CAA76155.1 xref: UniProtKB:Q15825 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016891 ! CHRNA6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 [Term] id: CCO:B0032799 name: ACHB3_HUMAN def: "Neuronal acetylcholine receptor subunit beta-3 precursor" [UniProtKB:Q05901] xref: EMBL:AAB40116.1 xref: EMBL:AAD33063.1 xref: EMBL:AAH69681.1 xref: EMBL:AAH69703.1 xref: EMBL:AAH69788.1 xref: EMBL:CAA47851.1 xref: EMBL:CAA69694.1 xref: UniProtKB:Q05901 xref: UniProtKB:Q15827 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016895 ! CHRNB3_human relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002725 ! channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0032804 name: ACHA3_HUMAN def: "Neuronal acetylcholine receptor subunit alpha-3 precursor" [UniProtKB:P32297] xref: EMBL:AAA59942.1 xref: EMBL:AAB40110.1 xref: EMBL:AAC84176.1 xref: EMBL:AAH00513.1 xref: EMBL:AAH01642.1 xref: EMBL:AAH02996.1 xref: EMBL:AAK68110.1 xref: EMBL:CAA07682.1 xref: EMBL:CAA37625.1 xref: EMBL:CAA69695.1 xref: UniProtKB:P32297 xref: UniProtKB:Q15823 xref: UniProtKB:Q96RH3 xref: UniProtKB:Q99553 xref: UniProtKB:Q9BQ93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016888 ! CHRNA3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0005634 ! acetylcholine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000713 ! activation of transmembrane receptor protein tyrosine kinase activity relationship: participates_in CCO:P0001075 ! regulation of acetylcholine secretion relationship: participates_in CCO:P0002900 ! regulation of dendrite morphogenesis [Term] id: CCO:B0032806 name: ACHA5_HUMAN def: "Neuronal acetylcholine receptor subunit alpha-5 precursor" [UniProtKB:P30532] xref: EMBL:AAA58357.1 xref: EMBL:AAB40112.1 xref: EMBL:AAH33639.1 xref: EMBL:CAA69696.1 xref: EMBL:CAC34820.1 xref: UniProtKB:P30532 xref: UniProtKB:Q15824 xref: UniProtKB:Q99554 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016890 ! CHRNA5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0032807 name: ACHB2_HUMAN def: "Neuronal acetylcholine receptor subunit beta-2 precursor" [UniProtKB:P17787] xref: EMBL:AAB40115.1 xref: EMBL:AAD45422.1 xref: EMBL:AAH75040.1 xref: EMBL:AAH75041.1 xref: EMBL:CAA05108.1 xref: EMBL:CAA37320.1 xref: EMBL:CAA69692.1 xref: UniProtKB:P17787 xref: UniProtKB:Q9UEH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016894 ! CHRNB2_human relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0005634 ! acetylcholine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001078 ! regulation of dopamine secretion relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0001563 ! regulation of synaptic transmission, dopaminergic relationship: participates_in CCO:P0001838 ! positive regulation of dopamine secretion relationship: participates_in CCO:P0002032 ! regulation of dopamine metabolic process relationship: participates_in CCO:P0002900 ! regulation of dendrite morphogenesis relationship: participates_in CCO:P0003166 ! regulation of synaptogenesis [Term] id: CCO:B0032809 name: ACHA2_HUMAN def: "Neuronal acetylcholine receptor subunit alpha-2 precursor" [UniProtKB:Q15822] xref: EMBL:AAB40109.1 xref: EMBL:AAI53867.1 xref: EMBL:CAA76154.1 xref: UniProtKB:A8KAX3 xref: UniProtKB:Q15822 xref: UniProtKB:Q9HAQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016887 ! CHRNA2_human relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0032819 name: ASNS_HUMAN def: "Asparagine synthetase [glutamine-hydrolyzing]" [UniProtKB:P08243] synonym: "Cell cycle control protein TS11" EXACT [UniProtKB:P08243] synonym: "EC 6.3.5.4" EXACT [UniProtKB:P08243] synonym: "Glutamine-dependent asparagine synthetase" EXACT [UniProtKB:P08243] xref: EMBL:AAA36781.1 xref: EMBL:AAA51789.1 xref: EMBL:AAA52756.1 xref: EMBL:AAA63266.1 xref: EMBL:AAH08723.1 xref: EMBL:AAH14621.1 xref: EMBL:AAP35777.1 xref: EMBL:AAQ96856.1 xref: UniProtKB:P08184 xref: UniProtKB:P08243 xref: UniProtKB:Q15666 xref: UniProtKB:Q549T9 xref: UniProtKB:Q96HD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006423 ! ASNS_human relationship: has_function CCO:F0000541 ! asparagine synthase (glutamine-hydrolyzing) activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008552 ! strn4-asns physical interaction relationship: participates_in CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0032820 name: ZN318_HUMAN def: "Zinc finger protein 318" [UniProtKB:Q5VUA4] synonym: "Endocrine regulatory protein" EXACT [UniProtKB:Q5VUA4] xref: EMBL:AAD17298.1 xref: EMBL:AAD47387.1 xref: EMBL:AAH30687.2 xref: EMBL:AAH98434.1 xref: EMBL:BAA34799.1 xref: EMBL:CAH71374.2 xref: EMBL:CAI14459.2 xref: UniProtKB:O94796 xref: UniProtKB:Q4G0E4 xref: UniProtKB:Q5VUA4 xref: UniProtKB:Q8NEM6 xref: UniProtKB:Q9UNU8 xref: UniProtKB:Q9Y2W9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006429 ! ZNF318_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0032863 ! ZN318_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0032864 ! ZN318_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0032865 ! ZN318_HUMAN-Phosphoserine464 relationship: transforms_into CCO:B0032866 ! ZN318_HUMAN-Phosphoserine550 relationship: transforms_into CCO:B0032867 ! ZN318_HUMAN-Phosphoserine1243 relationship: transforms_into CCO:B0032868 ! ZN318_HUMAN-Phosphoserine1623 relationship: transforms_into CCO:B0032869 ! ZN318_HUMAN-Phosphoserine1713 relationship: transforms_into CCO:B0032870 ! ZN318_HUMAN-Phosphoserine2101 relationship: transforms_into CCO:B0072097 ! ZN318_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0072098 ! ZN318_HUMAN-Phosphoserine81 relationship: transforms_into CCO:B0072099 ! ZN318_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0072100 ! ZN318_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0072101 ! ZN318_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0072102 ! ZN318_HUMAN-Phosphoserine1420 relationship: transforms_into CCO:B0072103 ! ZN318_HUMAN-Phosphoserine1896 relationship: transforms_into CCO:B0072104 ! ZN318_HUMAN-Phosphoserine2189 relationship: transforms_into CCO:B0072105 ! ZN318_HUMAN-Phosphoserine2192 relationship: transforms_into CCO:B0072106 ! ZN318_HUMAN-Phosphoserine2243 [Term] id: CCO:B0032821 name: ZWILC_HUMAN def: "Protein zwilch homolog" [UniProtKB:Q9H900] synonym: "hZwilch" EXACT [UniProtKB:Q9H900] xref: EMBL:AAH36900.1 xref: EMBL:AAH90041.1 xref: EMBL:BAA91414.1 xref: EMBL:BAB14446.1 xref: EMBL:BAB55133.1 xref: EMBL:CAE45821.1 xref: EMBL:EAW77779.1 xref: UniProtKB:Q6N049 xref: UniProtKB:Q8N404 xref: UniProtKB:Q96SY7 xref: UniProtKB:Q9H900 xref: UniProtKB:Q9NWG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006023 ! ZWILCH_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000104 ! mitotic cell cycle checkpoint relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0032831 name: PRDC1_HUMAN def: "Phosphoribosyltransferase domain-containing protein 1" [UniProtKB:Q9NRG1] xref: EMBL:AAF86956.1 xref: EMBL:AAH08662.1 xref: EMBL:BAB13944.1 xref: EMBL:BAD93029.1 xref: EMBL:BAD96394.1 xref: EMBL:CAH70349.1 xref: EMBL:CAH70350.1 xref: EMBL:CAH70351.1 xref: EMBL:CAH70785.1 xref: EMBL:CAH70786.1 xref: EMBL:CAH70787.1 xref: EMBL:EAW86120.1 xref: UniProtKB:Q53HA7 xref: UniProtKB:Q59EL9 xref: UniProtKB:Q5VV18 xref: UniProtKB:Q5VV20 xref: UniProtKB:Q9NRG1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006427 ! PRTFDC1_human relationship: has_function CCO:F0000831 ! hypoxanthine phosphoribosyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0005926 ! hhgp-stat5a physical interaction relationship: participates_in CCO:I0014952 ! ewsr1-hhgp physical interaction relationship: participates_in CCO:I0014996 ! hhgp-nif3l1 physical interaction relationship: participates_in CCO:I0015797 ! hhgp-hprt1 physical interaction [Term] id: CCO:B0032833 name: GDIR1_HUMAN def: "Rho GDP-dissociation inhibitor 1" [UniProtKB:P52565] synonym: "Rho GDI 1" EXACT [UniProtKB:P52565] synonym: "Rho-GDI alpha" EXACT [UniProtKB:P52565] xref: EMBL:AAA36566.1 xref: EMBL:AAH05851.1 xref: EMBL:AAH05875.1 xref: EMBL:AAH08701.1 xref: EMBL:AAH09759.1 xref: EMBL:AAH16031.1 xref: EMBL:AAH16185.1 xref: EMBL:AAH24258.1 xref: EMBL:AAH27730.1 xref: EMBL:AAH75827.1 xref: EMBL:AAM21074.1 xref: EMBL:AAP35530.1 xref: EMBL:BAA03096.1 xref: EMBL:CAA45344.1 xref: EMBL:CAA49281.1 xref: UniProtKB:P52565 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004692 ! ARHGDIA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008356 ! arhgdia-cdkn1b physical interaction relationship: participates_in CCO:I0016004 ! arhgdia-rac1-1 direct interaction relationship: participates_in CCO:I0017952 ! arhgdia-rhoa-1 direct interaction relationship: participates_in CCO:I0019651 ! arhgdia-fen1 physical interaction relationship: participates_in CCO:I0019897 ! arhgdia-jup physical interaction relationship: participates_in CCO:I0020234 ! arhgdia-baf53a physical interaction relationship: participates_in CCO:I0020235 ! arhgdia-nedd4l physical interaction relationship: participates_in CCO:I0020508 ! arhgdia-siat4c physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0032847 ! GDIR1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0032848 ! GDIR1_HUMAN-N6-acetyllysine141 [Term] id: CCO:B0032839 name: DBF4A_HUMAN-Phosphoserine381 def: "Protein DBF4A_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9UBU7] xref: UniProtKB:Q9UBU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002194 ! DBF4A_HUMAN [Term] id: CCO:B0032840 name: DBF4A_HUMAN-Phosphothreonine535 def: "Protein DBF4A_HUMAN with the residue 535 substituted with Phosphothreonine" [UniProtKB:Q9UBU7] xref: UniProtKB:Q9UBU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002194 ! DBF4A_HUMAN [Term] id: CCO:B0032841 name: DBF4A_HUMAN-Phosphoserine539 def: "Protein DBF4A_HUMAN with the residue 539 substituted with Phosphoserine" [UniProtKB:Q9UBU7] xref: UniProtKB:Q9UBU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0002194 ! DBF4A_HUMAN [Term] id: CCO:B0032842 name: DYHC1_HUMAN-Phosphoserine2410 def: "Protein DYHC1_HUMAN with the residue 2410 substituted with Phosphoserine" [UniProtKB:Q14204] xref: UniProtKB:Q14204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001780 ! DYHC1_HUMAN [Term] id: CCO:B0032843 name: DYHC1_HUMAN-Phosphotyrosine3379 def: "Protein DYHC1_HUMAN with the residue 3379 substituted with Phosphotyrosine" [UniProtKB:Q14204] comment: By similarity xref: UniProtKB:Q14204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001780 ! DYHC1_HUMAN [Term] id: CCO:B0032844 name: DYHC1_HUMAN-Phosphothreonine4218 def: "Protein DYHC1_HUMAN with the residue 4218 substituted with Phosphothreonine" [UniProtKB:Q14204] comment: By similarity xref: UniProtKB:Q14204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001780 ! DYHC1_HUMAN [Term] id: CCO:B0032845 name: DYHC1_HUMAN-Phosphothreonine4221 def: "Protein DYHC1_HUMAN with the residue 4221 substituted with Phosphothreonine" [UniProtKB:Q14204] comment: By similarity xref: UniProtKB:Q14204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001780 ! DYHC1_HUMAN [Term] id: CCO:B0032846 name: DYHC1_HUMAN-Phosphoserine4368 def: "Protein DYHC1_HUMAN with the residue 4368 substituted with Phosphoserine" [UniProtKB:Q14204] xref: UniProtKB:Q14204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001780 ! DYHC1_HUMAN [Term] id: CCO:B0032847 name: GDIR1_HUMAN-N-acetylalanine2 def: "Protein GDIR1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P52565] xref: UniProtKB:P52565 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032833 ! GDIR1_HUMAN [Term] id: CCO:B0032848 name: GDIR1_HUMAN-N6-acetyllysine141 def: "Protein GDIR1_HUMAN with the residue 141 substituted with N6-acetyllysine" [UniProtKB:P52565] xref: UniProtKB:P52565 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001399 ! Rho GDP-dissociation inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0032833 ! GDIR1_HUMAN [Term] id: CCO:B0032849 name: HOP2_HUMAN-Phosphoserine29 def: "Protein HOP2_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q9P2W1] xref: UniProtKB:Q9P2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032571 ! HOP2_HUMAN [Term] id: CCO:B0032850 name: MCM2_HUMAN-Phosphoserine53 def: "Protein MCM2_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:P49736] comment: by CDC7; xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0032851 name: MYH10_HUMAN-Phosphoserine1013 def: "Protein MYH10_HUMAN with the residue 1013 substituted with Phosphoserine" [UniProtKB:P35580] xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0032852 name: MYH10_HUMAN-Phosphoserine1938 def: "Protein MYH10_HUMAN with the residue 1938 substituted with Phosphoserine" [UniProtKB:P35580] comment: By similarity xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0032853 name: MYH10_HUMAN-Phosphoserine1952 def: "Protein MYH10_HUMAN with the residue 1952 substituted with Phosphoserine" [UniProtKB:P35580] xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0032854 name: MYH10_HUMAN-Phosphoserine1956 def: "Protein MYH10_HUMAN with the residue 1956 substituted with Phosphoserine" [UniProtKB:P35580] xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0032855 name: MYH10_HUMAN-Phosphothreonine1960 def: "Protein MYH10_HUMAN with the residue 1960 substituted with Phosphothreonine" [UniProtKB:P35580] xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000026 ! microfilament motor activity relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004599 ! actin-dependent ATPase activity relationship: has_function CCO:F0005867 ! ADP binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0001017 ! midbody relationship: located_in CCO:C0001403 ! cleavage furrow relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0032856 name: P53_HUMAN-N6-methyllysine370 def: "Protein P53_HUMAN with the residue 370 substituted with N6-methyllysine" [UniProtKB:P04637] xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0032857 name: P53_HUMAN-N6-methyllysine372 def: "Protein P53_HUMAN with the residue 372 substituted with N6-methyllysine" [UniProtKB:P04637] xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0032858 name: TAF10_HUMAN-N6-methyllysine189 def: "Protein TAF10_HUMAN with the residue 189 substituted with N6-methyllysine" [UniProtKB:Q12962] xref: UniProtKB:Q12962 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0005937 ! TAF10_HUMAN [Term] id: CCO:B0032859 name: TP53B_HUMAN-Phosphoserine166 def: "Protein TP53B_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0032860 name: TP53B_HUMAN-Phosphoserine176 def: "Protein TP53B_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q12888] comment: Probable xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0032861 name: TP53B_HUMAN-Phosphoserine178 def: "Protein TP53B_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q12888] comment: Probable xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0032862 name: TP53B_HUMAN-Phosphoserine452 def: "Protein TP53B_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0032863 name: ZN318_HUMAN-Phosphoserine305 def: "Protein ZN318_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032864 name: ZN318_HUMAN-Phosphoserine307 def: "Protein ZN318_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032865 name: ZN318_HUMAN-Phosphoserine464 def: "Protein ZN318_HUMAN with the residue 464 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032866 name: ZN318_HUMAN-Phosphoserine550 def: "Protein ZN318_HUMAN with the residue 550 substituted with Phosphoserine" [UniProtKB:Q5VUA4] comment: By similarity xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032867 name: ZN318_HUMAN-Phosphoserine1243 def: "Protein ZN318_HUMAN with the residue 1243 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032868 name: ZN318_HUMAN-Phosphoserine1623 def: "Protein ZN318_HUMAN with the residue 1623 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032869 name: ZN318_HUMAN-Phosphoserine1713 def: "Protein ZN318_HUMAN with the residue 1713 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032870 name: ZN318_HUMAN-Phosphoserine2101 def: "Protein ZN318_HUMAN with the residue 2101 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0032873 name: MND1_HUMAN def: "Meiotic nuclear division protein 1 homolog" [UniProtKB:Q9BWT6] xref: EMBL:AAH32142.1 xref: EMBL:AAK26168.1 xref: EMBL:EAX04964.1 xref: EMBL:EAX04965.1 xref: UniProtKB:Q9BWT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007828 ! MND1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0032938 name: ANGT_HUMAN def: "Angiotensinogen precursor" [UniProtKB:P01019] synonym: "Serpin A8" EXACT [UniProtKB:P01019] xref: EMBL:AAA51679.1 xref: EMBL:AAA51731.1 xref: EMBL:AAA52282.1 xref: EMBL:AAD14287.1 xref: EMBL:AAD14288.1 xref: EMBL:AAH11519.1 xref: EMBL:CAA33385.1 xref: UniProtKB:P01019 xref: UniProtKB:Q16358 xref: UniProtKB:Q16359 xref: UniProtKB:Q96F91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007246 ! AGT_human relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0004715 ! type 1 angiotensin receptor binding relationship: has_function CCO:F0004716 ! type 2 angiotensin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0015784 ! agt-ewsr1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000737 ! G-protein signaling, coupled to cGMP nucleotide second messenger relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0002520 ! positive regulation of fatty acid biosynthetic process relationship: participates_in CCO:P0002857 ! smooth muscle cell proliferation relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0003083 ! negative regulation of nerve growth factor receptor signaling pathway relationship: transforms_into CCO:B0065625 ! ANGT_HUMAN-aspartate34 [Term] id: CCO:B0032975 name: TBPL2_HUMAN def: "TATA box-binding protein-like protein 2" [UniProtKB:Q6SJ96] synonym: "TATA box-binding protein-related factor 3" EXACT [UniProtKB:Q6SJ96] synonym: "TBP-like protein 2" EXACT [UniProtKB:Q6SJ96] synonym: "TBP-related factor 3" EXACT [UniProtKB:Q6SJ96] xref: EMBL:AAI17160.1 xref: EMBL:AAI17186.1 xref: EMBL:AAR24281.1 xref: EMBL:ABD93323.1 xref: UniProtKB:Q17RU8 xref: UniProtKB:Q6SJ96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008276 ! TBPL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0032981 name: Q32MN6_HUMAN def: "TATA-box-binding protein" [UniProtKB:Q32MN6] xref: EMBL:AAI09055.1 xref: UniProtKB:Q32MN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005744 ! TBP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033001 name: RS27_HUMAN def: "40S ribosomal protein S27" [UniProtKB:P42677] synonym: "Metallopan-stimulin 1" EXACT [UniProtKB:P42677] synonym: "MPS-1" EXACT [UniProtKB:P42677] xref: EMBL:AAA59867.1 xref: EMBL:AAB02266.1 xref: EMBL:AAH02658.1 xref: EMBL:AAH70219.1 xref: EMBL:BAA25825.1 xref: EMBL:BAB79483.1 xref: UniProtKB:P42677 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008132 ! RPS27_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0016567 ! ikbkg-rps27 physical interaction relationship: participates_in CCO:I0016633 ! map3k1-rps27 physical interaction relationship: participates_in CCO:I0016770 ! map3k3-rps27 physical interaction relationship: participates_in CCO:I0016837 ! nfkb2-rps27 physical interaction relationship: participates_in CCO:I0016957 ! q9nyj8-rps27 physical interaction relationship: participates_in CCO:I0017022 ! tnfrsf1a-rps27 physical interaction relationship: participates_in CCO:I0017055 ! tnfrsf1b-rps27 physical interaction relationship: participates_in CCO:I0017086 ! tradd-rps27 physical interaction relationship: participates_in CCO:I0020658 ! rps27-masa physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0035601 ! RS27_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0035602 ! RS27_HUMAN-Phosphotyrosine31 relationship: transforms_into CCO:B0035603 ! RS27_HUMAN-Phosphoserine78 [Term] id: CCO:B0033014 name: SODC_HUMAN def: "Superoxide dismutase [Cu-Zn]" [UniProtKB:P00441] synonym: "EC 1.15.1.1" EXACT [UniProtKB:P00441] xref: EMBL:AAB05661.1 xref: EMBL:AAB05662.1 xref: EMBL:AAB59626.1 xref: EMBL:AAB59627.1 xref: EMBL:AAC41773.1 xref: EMBL:AAH01034.1 xref: EMBL:AAL15444.1 xref: EMBL:AAP35322.1 xref: EMBL:AAR21563.1 xref: EMBL:AAV80422.1 xref: EMBL:ABL96616.1 xref: EMBL:BAG35052.1 xref: EMBL:CAA25915.1 xref: EMBL:CAA25916.1 xref: EMBL:CAA25917.1 xref: EMBL:CAA25918.1 xref: EMBL:CAA25919.1 xref: EMBL:CAA26182.1 xref: EMBL:CAA64520.1 xref: EMBL:CAG29351.1 xref: EMBL:CAG46542.1 xref: EMBL:EAX09889.1 xref: UniProtKB:A6NHJ0 xref: UniProtKB:P00441 xref: UniProtKB:Q16669 xref: UniProtKB:Q16711 xref: UniProtKB:Q16838 xref: UniProtKB:Q16839 xref: UniProtKB:Q16840 xref: UniProtKB:Q6NR85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008196 ! SOD1_human relationship: has_function CCO:F0001144 ! superoxide dismutase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004400 ! protein phosphatase 2B binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001109 ! extracellular matrix relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001483 ! dendrite cytoplasm relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0001769 ! regulation of T cell differentiation in the thymus relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0002386 ! negative regulation of cholesterol biosynthetic process relationship: transforms_into CCO:B0035670 ! SODC_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0035671 ! SODC_HUMAN-N6-acetyllysine71 [Term] id: CCO:B0033027 name: FOXO6_HUMAN def: "Forkhead box protein O6" [UniProtKB:A8MYZ6] xref: UniProtKB:A8MYZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007552 ! FOXO6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0034805 ! FOXO6_HUMAN-Phosphoserine184 [Term] id: CCO:B0033110 name: Q16157_HUMAN def: "Integrin beta 3" [UniProtKB:Q16157] xref: EMBL:AAB30847.2 xref: UniProtKB:Q16157 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008533 ! integrin beta 3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033114 name: ITB4_HUMAN def: "Integrin beta-4 precursor" [UniProtKB:P16144] synonym: "CD104 antigen" EXACT [UniProtKB:P16144] synonym: "GP150" EXACT [UniProtKB:P16144] xref: EMBL:AAB65421.1 xref: EMBL:AAB65422.1 xref: EMBL:AAC51632.1 xref: EMBL:AAC51633.1 xref: EMBL:AAC51634.1 xref: EMBL:CAA36134.1 xref: EMBL:CAA36433.1 xref: EMBL:CAA37656.1 xref: EMBL:CAB61345.1 xref: UniProtKB:O14690 xref: UniProtKB:O14691 xref: UniProtKB:O15339 xref: UniProtKB:O15340 xref: UniProtKB:O15341 xref: UniProtKB:P16144 xref: UniProtKB:Q9UIQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007685 ! ITGB4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019043 ! atxn1-itgb4 physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0034894 ! ITB4_HUMAN-Phosphoserine1084 relationship: transforms_into CCO:B0034895 ! ITB4_HUMAN-Phosphotyrosine1207 relationship: transforms_into CCO:B0034896 ! ITB4_HUMAN-Phosphothreonine1530 [Term] id: CCO:B0033120 name: ITB5_HUMAN def: "Integrin beta-5 precursor" [UniProtKB:P18084] xref: EMBL:AAA52707.1 xref: EMBL:AAA59183.1 xref: EMBL:AAH06541.1 xref: EMBL:ABY87537.1 xref: EMBL:CAA37188.1 xref: UniProtKB:B0LPF8 xref: UniProtKB:P18084 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007686 ! ITGB5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033122 name: ITB2_HUMAN def: "Integrin beta-2 precursor" [UniProtKB:P05107] synonym: "CD18 antigen" EXACT [UniProtKB:P05107] synonym: "Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta" EXACT [UniProtKB:P05107] synonym: "Complement receptor C3 subunit beta" EXACT [UniProtKB:P05107] xref: EMBL:AAA59490.1 xref: EMBL:AAB21404.1 xref: EMBL:AAH05861.1 xref: EMBL:CAA45427.1 xref: EMBL:CAA68266.1 xref: EMBL:CAB90553.1 xref: UniProtKB:P05107 xref: UniProtKB:Q16418 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007683 ! ITGB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016217 ! itgb2-syk physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation relationship: transforms_into CCO:B0034885 ! ITB2_HUMAN-Pyrrolidone carboxylic acid23 relationship: transforms_into CCO:B0034886 ! ITB2_HUMAN-Phosphoserine745 relationship: transforms_into CCO:B0034887 ! ITB2_HUMAN-Phosphoserine756 relationship: transforms_into CCO:B0034888 ! ITB2_HUMAN-Phosphothreonine758 relationship: transforms_into CCO:B0034889 ! ITB2_HUMAN-Phosphothreonine759 relationship: transforms_into CCO:B0034890 ! ITB2_HUMAN-Phosphothreonine760 [Term] id: CCO:B0033125 name: ITB8_HUMAN def: "Integrin beta-8 precursor" [UniProtKB:P26012] xref: EMBL:AAA36034.1 xref: EMBL:AAQ96845.1 xref: UniProtKB:P26012 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007689 ! ITGB8_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033128 name: Q59FN1_HUMAN def: "Integrin beta" [UniProtKB:Q59FN1] xref: EMBL:BAD92666.1 xref: UniProtKB:Q59FN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033131 name: Q5T3E5_HUMAN def: "Integrin, beta 1 (Fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" [UniProtKB:Q5T3E5] xref: EMBL:CAI14428.1 xref: UniProtKB:Q5T3E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007682 ! ITGB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033132 name: Q59H50_HUMAN def: "Integrin beta" [UniProtKB:Q59H50] xref: EMBL:BAD92146.1 xref: UniProtKB:Q59H50 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033133 name: ITB6_HUMAN def: "Integrin beta-6 precursor" [UniProtKB:P18564] xref: EMBL:AAA36122.2 xref: EMBL:AAB23690.1 xref: EMBL:AAI21179.1 xref: EMBL:AAX93093.1 xref: EMBL:AAY24053.1 xref: UniProtKB:P18564 xref: UniProtKB:Q0VA95 xref: UniProtKB:Q16500 xref: UniProtKB:Q53RG5 xref: UniProtKB:Q53RR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007687 ! ITGB6_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033134 name: A8MYE6_HUMAN def: "Integrin beta" [UniProtKB:A8MYE6] xref: UniProtKB:A8MYE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007683 ! ITGB2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033136 name: Q8WUM6_HUMAN def: "Integrin beta" [UniProtKB:Q8WUM6] xref: EMBL:AAH20057.1 xref: EMBL:CAI14426.1 xref: EMBL:EAW85948.1 xref: UniProtKB:Q8WUM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007682 ! ITGB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033137 name: ITB7_HUMAN def: "Integrin beta-7 precursor" [UniProtKB:P26010] synonym: "Gut homing receptor beta subunit" EXACT [UniProtKB:P26010] xref: EMBL:AAA36118.1 xref: EMBL:AAA59184.1 xref: EMBL:AAA59185.1 xref: EMBL:AAB21332.1 xref: EMBL:AAB23688.1 xref: EMBL:AAH15916.1 xref: UniProtKB:P26010 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007688 ! ITGB7_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016290 ! itgb7-itgb7-1 physical interaction relationship: participates_in CCO:I0016301 ! itgb7-itgb7-2 physical interaction relationship: participates_in CCO:I0016305 ! itga4-itgb7-2 physical interaction relationship: participates_in CCO:I0016309 ! itgb7-itga4-1 physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0034897 ! ITB7_HUMAN-Phosphotyrosine778 [Term] id: CCO:B0033138 name: ITB1_HUMAN def: "Integrin beta-1 precursor" [UniProtKB:P05556] synonym: "CD29 antigen" EXACT [UniProtKB:P05556] synonym: "Fibronectin receptor subunit beta" EXACT [UniProtKB:P05556] synonym: "Integrin VLA-4 subunit beta" EXACT [UniProtKB:P05556] xref: EMBL:AAA59182.1 xref: EMBL:AAA74402.1 xref: EMBL:AAA74403.1 xref: EMBL:AAA79832.1 xref: EMBL:AAA79833.1 xref: EMBL:AAA79834.1 xref: EMBL:AAA79835.1 xref: EMBL:AAA81366.1 xref: EMBL:CAA30790.1 xref: UniProtKB:P05556 xref: UniProtKB:P78466 xref: UniProtKB:P78467 xref: UniProtKB:Q13089 xref: UniProtKB:Q13090 xref: UniProtKB:Q13091 xref: UniProtKB:Q13212 xref: UniProtKB:Q14622 xref: UniProtKB:Q14647 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007682 ! ITGB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016294 ! itgb1-itgb1-1 physical interaction relationship: participates_in CCO:I0016299 ! itgb1-itgb1-2 physical interaction relationship: participates_in CCO:I0016302 ! itga2-itgb1-1 physical interaction relationship: participates_in CCO:I0016304 ! itga4-itgb1-1 physical interaction relationship: participates_in CCO:I0016306 ! itgb1-itga2-1 physical interaction relationship: participates_in CCO:I0016307 ! itgb1-itga4-1 physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 [Term] id: CCO:B0033141 name: ITB3_HUMAN def: "Integrin beta-3 precursor" [UniProtKB:P05106] synonym: "CD61 antigen" EXACT [UniProtKB:P05106] synonym: "GPIIIa" EXACT [UniProtKB:P05106] synonym: "Platelet membrane glycoprotein IIIa" EXACT [UniProtKB:P05106] xref: EMBL:AAA16076.1 xref: EMBL:AAA20880.2 xref: EMBL:AAA35927.1 xref: EMBL:AAA36121.1 xref: EMBL:AAA52589.1 xref: EMBL:AAA52600.1 xref: EMBL:AAA60122.1 xref: EMBL:AAA67537.1 xref: EMBL:AAB23689.2 xref: EMBL:AAB71380.1 xref: EMBL:AAI27667.1 xref: EMBL:AAI27668.1 xref: UniProtKB:A0PJW2 xref: UniProtKB:O15495 xref: UniProtKB:P05106 xref: UniProtKB:Q12806 xref: UniProtKB:Q13413 xref: UniProtKB:Q14648 xref: UniProtKB:Q16499 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007684 ! ITGB3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001129 ! platelet alpha granule membrane relationship: participates_in CCO:I0016203 ! itgav-itgb3-3 direct interaction relationship: participates_in CCO:I0016295 ! itgb3-itgb3-3 physical interaction relationship: participates_in CCO:I0016300 ! itgb3-itgb3-4 physical interaction relationship: participates_in CCO:I0016303 ! itga2b-itgb3-1 physical interaction relationship: participates_in CCO:I0016308 ! itgb3-itga2b-1 physical interaction relationship: participates_in CCO:I0017271 ! itga2b-itgb3-2 direct interaction relationship: participates_in CCO:I0017514 ! itgb3-itgb3-2 direct interaction relationship: participates_in CCO:I0017784 ! itgav-itgb3-1 direct interaction relationship: participates_in CCO:I0017792 ! itgav-itgb3-2 direct interaction relationship: participates_in CCO:I0019266 ! itgb3-itgb3-1 direct interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: transforms_into CCO:B0034891 ! ITB3_HUMAN-Phosphotyrosine773 relationship: transforms_into CCO:B0034892 ! ITB3_HUMAN-Phosphothreonine779 relationship: transforms_into CCO:B0034893 ! ITB3_HUMAN-Phosphotyrosine785 [Term] id: CCO:B0033143 name: Q5T3E4_HUMAN def: "Integrin, beta 1 (Fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)" [UniProtKB:Q5T3E4] xref: EMBL:CAI14429.1 xref: UniProtKB:Q5T3E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007682 ! ITGB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0033164 name: AGR2_HUMAN def: "Anterior gradient protein 2 homolog precursor" [UniProtKB:O95994] synonym: "AG-2" EXACT [UniProtKB:O95994] synonym: "hAG-2" EXACT [UniProtKB:O95994] synonym: "HPC8" EXACT [UniProtKB:O95994] synonym: "Secreted cement gland protein XAG-2 homolog" EXACT [UniProtKB:O95994] xref: EMBL:AAC77358.1 xref: EMBL:AAC82614.1 xref: EMBL:AAF22484.1 xref: EMBL:AAH15503.1 xref: EMBL:AAL54870.1 xref: EMBL:AAP22354.1 xref: EMBL:AAP35697.1 xref: EMBL:AAP97179.1 xref: EMBL:AAQ89368.1 xref: UniProtKB:O95994 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007223 ! AGR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019645 ! agr2-med31 physical interaction [Term] id: CCO:B0033173 name: Q59FU8_HUMAN def: "Tumor necrosis factor receptor superfamily, member 6 isoform 1 variant" [UniProtKB:Q59FU8] xref: EMBL:BAD92598.1 xref: UniProtKB:Q59FU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0033174 name: Q5T9P3_HUMAN def: "Fas (TNF receptor superfamily, member 6)" [UniProtKB:Q5T9P3] xref: EMBL:CAI13870.1 xref: UniProtKB:Q5T9P3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005805 ! FAS_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0033210 name: SGK2_HUMAN def: "Serine/threonine-protein kinase Sgk2" [UniProtKB:Q9HBY8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9HBY8] synonym: "Serum/glucocorticoid-regulated kinase 2" EXACT [UniProtKB:Q9HBY8] xref: EMBL:AAF12757.2 xref: EMBL:AAG17012.1 xref: EMBL:AAH14037.3 xref: EMBL:AAH65511.1 xref: EMBL:AAV38901.1 xref: EMBL:AAX88805.1 xref: EMBL:CAC18509.1 xref: EMBL:CAI42312.1 xref: EMBL:CAI42315.1 xref: UniProtKB:Q52PK5 xref: UniProtKB:Q5H8Y6 xref: UniProtKB:Q5H8Z1 xref: UniProtKB:Q5TZR3 xref: UniProtKB:Q9HBY8 xref: UniProtKB:Q9UKG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008180 ! SGK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0035648 ! SGK2_HUMAN-Phosphothreonine253 relationship: transforms_into CCO:B0035649 ! SGK2_HUMAN-Phosphoserine416 [Term] id: CCO:B0033252 name: OPSX_HUMAN def: "Visual pigment-like receptor peropsin" [UniProtKB:O14718] xref: EMBL:AAC51757.1 xref: EMBL:DAA00976.1 xref: UniProtKB:O14718 xref: UniProtKB:Q7RTS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007920 ! RRH_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033253 name: A6NEB4_HUMAN def: "Putative uncharacterized protein OPN4" [UniProtKB:A6NEB4] xref: UniProtKB:A6NEB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007919 ! OPN4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033254 name: OPN4_HUMAN def: "Melanopsin" [UniProtKB:Q9UHM6] synonym: "Opsin-4" EXACT [UniProtKB:Q9UHM6] xref: EMBL:AAF24978.1 xref: EMBL:AAI13559.1 xref: EMBL:ABC40723.1 xref: EMBL:BAC05951.1 xref: UniProtKB:Q14D01 xref: UniProtKB:Q2PP22 xref: UniProtKB:Q8NGQ9 xref: UniProtKB:Q9UHM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007919 ! OPN4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001640 ! 11-cis retinal binding relationship: has_function CCO:F0001680 ! G-protein coupled photoreceptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033309 name: COF2_HUMAN def: "Cofilin-2" [UniProtKB:Q9Y281] synonym: "Cofilin, muscle isoform" EXACT [UniProtKB:Q9Y281] xref: EMBL:AAD31280.1 xref: EMBL:AAD31281.1 xref: EMBL:AAF64498.1 xref: EMBL:AAF97934.1 xref: EMBL:AAH11444.1 xref: EMBL:AAH22364.1 xref: EMBL:AAH22876.1 xref: UniProtKB:Q9Y281 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007409 ! CFL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016761 ! map3k3-cfl2 physical interaction relationship: transforms_into CCO:B0034678 ! COF2_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0034679 ! COF2_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0034680 ! COF2_HUMAN-Phosphotyrosine89 relationship: transforms_into CCO:B0043235 ! COF2_HUMAN-N-acetylalanine2 [Term] id: CCO:B0033316 name: DEST_HUMAN def: "Destrin" [UniProtKB:P60981] synonym: "Actin-depolymerizing factor" EXACT [UniProtKB:P60981] synonym: "ADF" EXACT [UniProtKB:P60981] xref: EMBL:AAB28361.1 xref: EMBL:AAH09477.1 xref: EMBL:CAC10585.1 xref: EMBL:CAG33323.1 xref: UniProtKB:P18282 xref: UniProtKB:P60981 xref: UniProtKB:Q5W166 xref: UniProtKB:Q6IAW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007455 ! DSTN_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0001056 ! cortical actin cytoskeleton relationship: participates_in CCO:I0015597 ! actg1-dstn physical interaction relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0001329 ! positive regulation of actin filament depolymerization relationship: transforms_into CCO:B0034697 ! DEST_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0034698 ! DEST_HUMAN-Phosphoserine3 [Term] id: CCO:B0033320 name: COF1_HUMAN def: "Cofilin-1" [UniProtKB:P23528] synonym: "18 kDa phosphoprotein" EXACT [UniProtKB:P23528] synonym: "Cofilin, non-muscle isoform" EXACT [UniProtKB:P23528] synonym: "p18" EXACT [UniProtKB:P23528] xref: EMBL:AAA64501.1 xref: EMBL:AAH11005.1 xref: EMBL:AAH12265.1 xref: EMBL:AAH12318.1 xref: EMBL:AAH18256.1 xref: EMBL:AAP35492.1 xref: EMBL:BAA00589.1 xref: EMBL:CAA64685.1 xref: UniProtKB:P23528 xref: UniProtKB:Q53Y87 xref: UniProtKB:Q9UCA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007408 ! CFL1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015123 ! actg1-cfl1 physical interaction relationship: participates_in CCO:I0016180 ! atxn1-cfl1 physical interaction relationship: participates_in CCO:I0017351 ! ywhaz-cof1-1 physical interaction relationship: participates_in CCO:I0017495 ! ywhaz-cof1-2 physical interaction relationship: participates_in CCO:I0018947 ! atxn1-cfl1-1 physical interaction relationship: participates_in CCO:I0018967 ! atxn1-cfl1-2 physical interaction relationship: participates_in CCO:I0019072 ! atxn1-cfl1-3 physical interaction relationship: participates_in CCO:I0019086 ! atxn1-cfl1-4 physical interaction relationship: participates_in CCO:I0020377 ! mycbp-cfl1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0034671 ! COF1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0034672 ! COF1_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0034673 ! COF1_HUMAN-Phosphothreonine25 relationship: transforms_into CCO:B0034674 ! COF1_HUMAN-Phosphotyrosine68 relationship: transforms_into CCO:B0034675 ! COF1_HUMAN-N6-acetyllysine132 relationship: transforms_into CCO:B0034676 ! COF1_HUMAN-Phosphotyrosine140 relationship: transforms_into CCO:B0034677 ! COF1_HUMAN-Phosphoserine156 [Term] id: CCO:B0033323 name: RGS12_HUMAN def: "Regulator of G-protein signaling 12" [UniProtKB:O14924] synonym: "RGS12" EXACT [UniProtKB:O14924] xref: EMBL:AAB84007.1 xref: EMBL:AAB84114.1 xref: EMBL:AAB84186.1 xref: EMBL:AAB84187.1 xref: EMBL:AAB96644.1 xref: EMBL:AAB96645.1 xref: EMBL:AAB96646.1 xref: EMBL:AAC39835.1 xref: UniProtKB:O14922 xref: UniProtKB:O14923 xref: UniProtKB:O14924 xref: UniProtKB:O43510 xref: UniProtKB:O75338 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008087 ! RGS12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0035550 ! RGS12_HUMAN-Phosphoserine874 relationship: transforms_into CCO:B0035551 ! RGS12_HUMAN-Phosphoserine889 relationship: transforms_into CCO:B0035552 ! RGS12_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0035553 ! RGS12_HUMAN-Phosphoserine940 [Term] id: CCO:B0033332 name: RGS14_HUMAN def: "Regulator of G-protein signaling 14" [UniProtKB:O43566] synonym: "RGS14" EXACT [UniProtKB:O43566] xref: EMBL:AAB92613.1 xref: EMBL:AAB92614.1 xref: EMBL:AAH14094.1 xref: EMBL:AAM12650.1 xref: EMBL:AAY26402.1 xref: EMBL:BAC85600.1 xref: UniProtKB:O43565 xref: UniProtKB:O43566 xref: UniProtKB:Q506M1 xref: UniProtKB:Q6ZWA4 xref: UniProtKB:Q8TD62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008089 ! RGS14_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015619 ! rgs14-traf2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0033333 name: RGS10_HUMAN def: "Regulator of G-protein signaling 10" [UniProtKB:O43665] synonym: "RGS10" EXACT [UniProtKB:O43665] xref: EMBL:AAC03783.1 xref: EMBL:AAH09361.1 xref: EMBL:AAK52979.1 xref: EMBL:AAM12648.1 xref: EMBL:CAG33289.1 xref: EMBL:CAI16486.1 xref: EMBL:EAW49389.1 xref: UniProtKB:O43665 xref: UniProtKB:Q6IAZ6 xref: UniProtKB:Q96GN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008086 ! RGS10_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0033334 name: Q147X0_HUMAN def: "RGS12 protein" [UniProtKB:Q147X0] xref: EMBL:AAI18595.1 xref: UniProtKB:Q147X0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008087 ! RGS12_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0033335 name: Q6IFC7_HUMAN def: "Olfactory receptor OR11-178 (Olfactory receptor, family 5, subfamily T, member 3)" [UniProtKB:Q6IFC7] xref: EMBL:DAA04733.1 xref: EMBL:EAW73705.1 xref: UniProtKB:Q6IFC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007932 ! OR5T3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033337 name: A8MTX1_HUMAN def: "Putative uncharacterized protein OR5AC2" [UniProtKB:A8MTX1] xref: UniProtKB:A8MTX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007909 ! OR5AC2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033338 name: OR5T1_HUMAN def: "Olfactory receptor 5T1" [UniProtKB:Q8NG75] synonym: "Olfactory receptor OR11-179" EXACT [UniProtKB:Q8NG75] xref: EMBL:BAC06174.1 xref: EMBL:DAA04734.1 xref: UniProtKB:Q8NG75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007930 ! OR5T1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033339 name: A8MW53_HUMAN def: "Putative uncharacterized protein OR5T3" [UniProtKB:A8MW53] xref: UniProtKB:A8MW53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007932 ! OR5T3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033340 name: O5AK3_HUMAN def: "Putative olfactory receptor 5AK3" [UniProtKB:Q8NH89] xref: EMBL:BAC05748.1 xref: UniProtKB:Q8NH89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007910 ! OR5AK3P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033341 name: OR5K4_HUMAN def: "Olfactory receptor 5K4" [UniProtKB:A6NMS3] xref: EMBL:EAW79864.1 xref: UniProtKB:A6NMS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007929 ! OR5K4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033342 name: A8MWJ9_HUMAN def: "Putative uncharacterized protein OR5H14" [UniProtKB:A8MWJ9] xref: UniProtKB:A8MWJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007911 ! OR5H14_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033343 name: Q6IFC8_HUMAN def: "Olfactory receptor OR11-177" [UniProtKB:Q6IFC8] xref: EMBL:DAA04732.1 xref: UniProtKB:Q6IFC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033344 name: OR9Q2_HUMAN def: "Olfactory receptor 9Q2" [UniProtKB:Q8NGE9] xref: EMBL:BAC06077.1 xref: UniProtKB:Q8NGE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007933 ! OR9Q2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033345 name: A8MXY9_HUMAN def: "Putative uncharacterized protein OR5H15" [UniProtKB:A8MXY9] xref: UniProtKB:A8MXY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007912 ! OR5H15_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033346 name: OR5I1_HUMAN def: "Olfactory receptor 5I1" [UniProtKB:Q13606] synonym: "Olfactory receptor OR11-159" EXACT [UniProtKB:Q13606] synonym: "Olfactory receptor-like protein OLF1" EXACT [UniProtKB:Q13606] xref: EMBL:AAB01214.1 xref: EMBL:AAH69093.1 xref: EMBL:DAA04916.1 xref: UniProtKB:Q13606 xref: UniProtKB:Q6IEU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007924 ! OR5I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033347 name: O5AC1_HUMAN def: "Olfactory receptor 5AC1" [UniProtKB:P0C628] synonym: "Olfactory receptor OR3-2" EXACT [UniProtKB:P0C628] xref: UniProtKB:P0C628 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014863 ! OR5AC1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033348 name: A8MVK2_HUMAN def: "Putative uncharacterized protein OR5H1" [UniProtKB:A8MVK2] xref: UniProtKB:A8MVK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007921 ! OR5H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033349 name: O5H14_HUMAN def: "Olfactory receptor 5H14" [UniProtKB:A6NHG9] xref: UniProtKB:A6NHG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007911 ! OR5H14_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033351 name: Q8IXE7_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8IXE7] xref: EMBL:BAC45256.1 xref: UniProtKB:Q8IXE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0033364 name: RUFY3_HUMAN def: "Protein RUFY3" [UniProtKB:Q7L099] synonym: "Rap2-interacting protein x" EXACT [UniProtKB:Q7L099] synonym: "RIPx" EXACT [UniProtKB:Q7L099] synonym: "Singar" EXACT [UniProtKB:Q7L099] synonym: "Single axon-regulated protein" EXACT [UniProtKB:Q7L099] xref: EMBL:AAF17208.1 xref: EMBL:AAH51716.1 xref: EMBL:BAA74894.2 xref: UniProtKB:O94948 xref: UniProtKB:Q7L099 xref: UniProtKB:Q9UI00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008136 ! RUFY3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0020437 ! ripx-unc119 physical interaction relationship: participates_in CCO:P0002949 ! negative regulation of axonogenesis [Term] id: CCO:B0033365 name: LASS4_HUMAN def: "LAG1 longevity assurance homolog 4" [UniProtKB:Q9HA82] xref: EMBL:AAH09828.1 xref: EMBL:BAB13972.1 xref: UniProtKB:Q9HA82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007775 ! LASS4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033366 name: LASS3_HUMAN def: "LAG1 longevity assurance homolog 3" [UniProtKB:Q8IU89] xref: EMBL:AAH28703.1 xref: EMBL:AAH34500.1 xref: EMBL:AAH34970.1 xref: UniProtKB:Q8IU89 xref: UniProtKB:Q8NE64 xref: UniProtKB:Q8NEN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007774 ! LASS3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033369 name: LASS6_HUMAN def: "LAG1 longevity assurance homolog 6" [UniProtKB:Q6ZMG9] xref: EMBL:AAH30800.2 xref: EMBL:BAD18757.1 xref: UniProtKB:Q6ZMG9 xref: UniProtKB:Q8N617 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007777 ! LASS6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033374 name: Q5SZE3_HUMAN def: "LAG1 homolog, ceramide synthase 2" [UniProtKB:Q5SZE3] xref: EMBL:CAI13332.1 xref: UniProtKB:Q5SZE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007773 ! LASS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033375 name: LASS2_HUMAN def: "LAG1 longevity assurance homolog 2" [UniProtKB:Q96G23] synonym: "SP260" EXACT [UniProtKB:Q96G23] synonym: "Tumor metastasis-suppressor gene 1 protein" EXACT [UniProtKB:Q96G23] xref: EMBL:AAF01058.4 xref: EMBL:AAG17982.2 xref: EMBL:AAH01357.2 xref: EMBL:AAH10032.1 xref: EMBL:AAM12028.1 xref: EMBL:BAA91505.1 xref: UniProtKB:Q96G23 xref: UniProtKB:Q9HD96 xref: UniProtKB:Q9NW79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007773 ! LASS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019193 ! lass2-asgr1 physical interaction relationship: participates_in CCO:I0019194 ! lass2-asgr2 physical interaction relationship: participates_in CCO:I0019195 ! lass2-atp6v0c physical interaction relationship: participates_in CCO:I0019332 ! asgr1-lass2 direct interaction relationship: participates_in CCO:I0019333 ! asgr2-lass2 direct interaction relationship: participates_in CCO:I0019334 ! hoct1-lass2-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035088 ! LASS2_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0035089 ! LASS2_HUMAN-Phosphothreonine346 relationship: transforms_into CCO:B0035090 ! LASS2_HUMAN-Phosphoserine348 relationship: transforms_into CCO:B0035091 ! LASS2_HUMAN-Phosphoserine349 [Term] id: CCO:B0033376 name: Q5SZE4_HUMAN def: "LAG1 homolog, ceramide synthase 2" [UniProtKB:Q5SZE4] xref: EMBL:CAI13331.1 xref: UniProtKB:Q5SZE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007773 ! LASS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033378 name: LASS5_HUMAN def: "LAG1 longevity assurance homolog 5" [UniProtKB:Q8N5B7] xref: EMBL:AAH32565.1 xref: UniProtKB:Q8N5B7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007776 ! LASS5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035092 ! LASS5_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0035093 ! LASS5_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0035095 ! LASS5_HUMAN-Phosphoserine356 [Term] id: CCO:B0033381 name: Q5SZE2_HUMAN def: "LAG1 homolog, ceramide synthase 2" [UniProtKB:Q5SZE2] xref: EMBL:CAI13333.1 xref: UniProtKB:Q5SZE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007773 ! LASS2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033382 name: Q32M63_HUMAN def: "LASS6 protein" [UniProtKB:Q32M63] xref: EMBL:AAI09285.1 xref: EMBL:AAI09286.1 xref: UniProtKB:Q32M63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007777 ! LASS6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033383 name: A8K4M4_HUMAN def: "cDNA FLJ75329, highly similar to Homo sapiens LAG1 longevity assurance homolog 2 (S. cerevisiae), transcript variant 2, mRNA" [UniProtKB:A8K4M4] xref: EMBL:BAF83678.1 xref: UniProtKB:A8K4M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033384 name: Q49AQ3_HUMAN def: "LASS5 protein" [UniProtKB:Q49AQ3] xref: EMBL:AAH33558.1 xref: UniProtKB:Q49AQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007776 ! LASS5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0033402 name: Q14CE0_HUMAN def: "GPR64 protein" [UniProtKB:Q14CE0] xref: EMBL:AAI13980.1 xref: UniProtKB:Q14CE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033403 name: Q6F3F5_HUMAN def: "Developmentally regulated G-protein-coupled receptor beta 2" [UniProtKB:Q6F3F5] xref: EMBL:BAD27574.1 xref: UniProtKB:Q6F3F5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008743 ! DREG_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033404 name: Q6F3F6_HUMAN def: "Developmentally regulated G-protein-coupled receptor beta 1" [UniProtKB:Q6F3F6] xref: EMBL:BAD27573.1 xref: UniProtKB:Q6F3F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007601 ! GPR126_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033405 name: GP126_HUMAN def: "Probable G-protein coupled receptor 126 precursor" [UniProtKB:Q86SQ4] xref: EMBL:AAO27356.1 xref: EMBL:AAR88427.1 xref: EMBL:BAB55406.1 xref: EMBL:BAC11393.1 xref: EMBL:CAE45930.1 xref: EMBL:CAE45986.1 xref: EMBL:CAI20053.1 xref: UniProtKB:Q5TGN7 xref: UniProtKB:Q6MZU7 xref: UniProtKB:Q86SQ4 xref: UniProtKB:Q8NC14 xref: UniProtKB:Q96JW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007601 ! GPR126_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0066525 ! GP126_HUMAN-Phosphoserine1162 relationship: transforms_into CCO:B0066526 ! GP126_HUMAN-Phosphoserine1165 [Term] id: CCO:B0033406 name: A2A2J1_HUMAN def: "G protein-coupled receptor 112" [UniProtKB:A2A2J1] xref: EMBL:CAI40998.2 xref: EMBL:CAM21579.1 xref: EMBL:CAM28220.1 xref: UniProtKB:A2A2J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007600 ! GPR112_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033407 name: A2A2J2_HUMAN def: "G protein-coupled receptor 112" [UniProtKB:A2A2J2] xref: EMBL:CAM21249.1 xref: EMBL:CAM21580.1 xref: EMBL:CAM28221.1 xref: UniProtKB:A2A2J2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007600 ! GPR112_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033410 name: A9Z1X2_HUMAN def: "Putative uncharacterized protein GPR64 (G protein-coupled receptor 64)" [UniProtKB:A9Z1X2] xref: EMBL:CAI40672.1 xref: EMBL:CAI41679.1 xref: UniProtKB:A9Z1X2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033411 name: Q6F3F8_HUMAN def: "Developmentally regulated G-protein-coupled receptor alpha 1" [UniProtKB:Q6F3F8] xref: EMBL:BAD27571.1 xref: UniProtKB:Q6F3F8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008743 ! DREG_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033412 name: GP112_HUMAN def: "Probable G-protein coupled receptor 112" [UniProtKB:Q8IZF6] xref: EMBL:AAN46668.1 xref: EMBL:AAO85093.1 xref: UniProtKB:Q86SM6 xref: UniProtKB:Q8IZF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007600 ! GPR112_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033414 name: Q499H0_HUMAN def: "G protein-coupled receptor 64" [UniProtKB:Q499H0] xref: EMBL:AAH99901.1 xref: UniProtKB:Q499H0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033415 name: Q5EGP2_HUMAN def: "G protein-coupled receptor 112" [UniProtKB:Q5EGP2] xref: EMBL:AAW78659.1 xref: UniProtKB:Q5EGP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007600 ! GPR112_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033418 name: GPR64_HUMAN def: "G-protein coupled receptor 64 precursor" [UniProtKB:Q8IZP9] synonym: "Epididymis-specific protein 6" EXACT [UniProtKB:Q8IZP9] synonym: "He6 receptor" EXACT [UniProtKB:Q8IZP9] xref: EMBL:AAN33056.1 xref: EMBL:AAN33064.1 xref: EMBL:AAN33065.1 xref: EMBL:AAN38971.1 xref: EMBL:AAN38972.1 xref: EMBL:AAN38973.1 xref: EMBL:AAN38974.1 xref: EMBL:AAN75702.1 xref: EMBL:CAA57479.1 xref: UniProtKB:O00406 xref: UniProtKB:Q8IWT2 xref: UniProtKB:Q8IZE4 xref: UniProtKB:Q8IZE5 xref: UniProtKB:Q8IZE6 xref: UniProtKB:Q8IZE7 xref: UniProtKB:Q8IZP3 xref: UniProtKB:Q8IZP4 xref: UniProtKB:Q8IZP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0034838 ! GPR64_HUMAN-Phosphoserine1010 [Term] id: CCO:B0033419 name: Q6F3F7_HUMAN def: "Developmentally regulated G-protein-coupled receptor alpha 2" [UniProtKB:Q6F3F7] xref: EMBL:BAD27572.1 xref: UniProtKB:Q6F3F7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008743 ! DREG_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0033427 name: NMDE1_HUMAN def: "Glutamate [NMDA] receptor subunit epsilon-1 precursor" [UniProtKB:Q12879] synonym: "hNR2A" EXACT [UniProtKB:Q12879] synonym: "N-methyl D-aspartate receptor subtype 2A" EXACT [UniProtKB:Q12879] synonym: "NMDAR2A" EXACT [UniProtKB:Q12879] synonym: "NR2A" EXACT [UniProtKB:Q12879] xref: EMBL:AAB49992.1 xref: EMBL:AAB60343.1 xref: UniProtKB:O00669 xref: UniProtKB:Q12879 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007881 ! GRIN2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000750 ! glutamate signaling pathway relationship: participates_in CCO:P0002784 ! regulation of synaptic plasticity relationship: transforms_into CCO:B0035267 ! NMDE1_HUMAN-Phosphothreonine888 relationship: transforms_into CCO:B0035268 ! NMDE1_HUMAN-Phosphoserine912 relationship: transforms_into CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: transforms_into CCO:B0035270 ! NMDE1_HUMAN-Phosphoserine929 relationship: transforms_into CCO:B0035271 ! NMDE1_HUMAN-Phosphotyrosine943 relationship: transforms_into CCO:B0035272 ! NMDE1_HUMAN-Phosphoserine1025 relationship: transforms_into CCO:B0035273 ! NMDE1_HUMAN-Phosphoserine1337 relationship: transforms_into CCO:B0035274 ! NMDE1_HUMAN-Phosphoserine1459 [Term] id: CCO:B0033431 name: NMDE2_HUMAN def: "Glutamate [NMDA] receptor subunit epsilon-2 precursor" [UniProtKB:Q13224] synonym: "hNR3" EXACT [UniProtKB:Q13224] synonym: "N-methyl D-aspartate receptor subtype 2B" EXACT [UniProtKB:Q13224] synonym: "N-methyl-D-aspartate receptor subunit 3" EXACT [UniProtKB:Q13224] synonym: "NMDAR2B" EXACT [UniProtKB:Q13224] synonym: "NR2B" EXACT [UniProtKB:Q13224] synonym: "NR3" EXACT [UniProtKB:Q13224] xref: EMBL:AAA69919.1 xref: EMBL:AAA69920.1 xref: EMBL:AAA74930.1 xref: EMBL:AAB49993.1 xref: EMBL:AAB60368.1 xref: EMBL:AAD00659.1 xref: EMBL:AAI13619.1 xref: EMBL:AAI13621.1 xref: UniProtKB:Q12919 xref: UniProtKB:Q13220 xref: UniProtKB:Q13224 xref: UniProtKB:Q13225 xref: UniProtKB:Q14CU4 xref: UniProtKB:Q9UM56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007882 ! GRIN2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000750 ! glutamate signaling pathway relationship: participates_in CCO:P0001070 ! positive regulation of glutamate secretion relationship: participates_in CCO:P0002209 ! regulation of MAPKKK cascade relationship: transforms_into CCO:B0035275 ! NMDE2_HUMAN-Phosphoserine917 relationship: transforms_into CCO:B0035276 ! NMDE2_HUMAN-Phosphoserine930 relationship: transforms_into CCO:B0035277 ! NMDE2_HUMAN-Phosphotyrosine932 relationship: transforms_into CCO:B0035278 ! NMDE2_HUMAN-Phosphotyrosine949 relationship: transforms_into CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: transforms_into CCO:B0035280 ! NMDE2_HUMAN-Phosphotyrosine1039 relationship: transforms_into CCO:B0035281 ! NMDE2_HUMAN-Phosphotyrosine1049 relationship: transforms_into CCO:B0035282 ! NMDE2_HUMAN-Phosphoserine1061 relationship: transforms_into CCO:B0035283 ! NMDE2_HUMAN-Phosphothreonine1065 relationship: transforms_into CCO:B0035284 ! NMDE2_HUMAN-Phosphotyrosine1070 relationship: transforms_into CCO:B0035285 ! NMDE2_HUMAN-Phosphotyrosine1109 relationship: transforms_into CCO:B0035286 ! NMDE2_HUMAN-Phosphotyrosine1155 relationship: transforms_into CCO:B0035287 ! NMDE2_HUMAN-Phosphoserine1166 relationship: transforms_into CCO:B0035288 ! NMDE2_HUMAN-Phosphotyrosine1252 relationship: transforms_into CCO:B0035289 ! NMDE2_HUMAN-Phosphoserine1303 relationship: transforms_into CCO:B0035290 ! NMDE2_HUMAN-Phosphotyrosine1304 relationship: transforms_into CCO:B0035291 ! NMDE2_HUMAN-Phosphotyrosine1474 [Term] id: CCO:B0033433 name: NMDE4_HUMAN def: "Glutamate [NMDA] receptor subunit epsilon-4 precursor" [UniProtKB:O15399] synonym: "EB11" EXACT [UniProtKB:O15399] synonym: "N-methyl D-aspartate receptor subtype 2D" EXACT [UniProtKB:O15399] synonym: "NMDAR2D" EXACT [UniProtKB:O15399] synonym: "NR2D" EXACT [UniProtKB:O15399] xref: EMBL:AAC15910.1 xref: UniProtKB:O15399 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007884 ! GRIN2D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035292 ! NMDE4_HUMAN-Phosphoserine1326 [Term] id: CCO:B0033471 name: F261_HUMAN def: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" [UniProtKB:P16118] synonym: "6PF-2-K/Fru-2,6-P2ASE liver isozyme" EXACT [UniProtKB:P16118] xref: EMBL:AAA35818.1 xref: EMBL:AAH96079.1 xref: EMBL:CAA36861.1 xref: EMBL:CAI42048.1 xref: EMBL:CAI43127.1 xref: UniProtKB:P16118 xref: UniProtKB:Q5JXS5 xref: UniProtKB:Q99951 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007513 ! PFKFB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017890 ! gck-pfkfb1-1 direct interaction relationship: participates_in CCO:I0018075 ! gck-pfkfb1-2 direct interaction relationship: participates_in CCO:I0018204 ! pfkfb1-1 direct interaction relationship: participates_in CCO:I0019401 ! pfkfb1-pfkb1_human direct interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0034772 ! F261_HUMAN-Phosphoserine33 [Term] id: CCO:B0033477 name: LRP8_HUMAN def: "Low-density lipoprotein receptor-related protein 8 precursor" [UniProtKB:Q14114] synonym: "Apolipoprotein E receptor 2" EXACT [UniProtKB:Q14114] xref: EMBL:AAH06443.1 xref: EMBL:AAH51836.2 xref: EMBL:BAA09328.1 xref: EMBL:BAA21824.1 xref: EMBL:BAA21825.1 xref: EMBL:CAA99509.1 xref: EMBL:CAI18908.1 xref: EMBL:CAI22781.1 xref: UniProtKB:B1AMT6 xref: UniProtKB:O14968 xref: UniProtKB:Q14114 xref: UniProtKB:Q86V27 xref: UniProtKB:Q99876 xref: UniProtKB:Q9BR78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007799 ! LRP8_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_function CCO:F0004350 ! apolipoprotein E receptor activity relationship: has_function CCO:F0004352 ! very-low-density lipoprotein receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0033478 name: DBF4B_HUMAN def: "Protein DBF4 homolog B" [UniProtKB:Q8NFT6] synonym: "Activator of S phase kinase-like protein 1" EXACT [UniProtKB:Q8NFT6] synonym: "ASK-like protein 1" EXACT [UniProtKB:Q8NFT6] synonym: "Chiffon homolog B" EXACT [UniProtKB:Q8NFT6] synonym: "Dbf4-related factor 1" EXACT [UniProtKB:Q8NFT6] xref: EMBL:AAH16158.1 xref: EMBL:AAL75985.1 xref: EMBL:AAM73808.1 xref: EMBL:BAB14431.1 xref: EMBL:EAW51581.1 xref: EMBL:EAW51584.1 xref: EMBL:EAW51587.1 xref: UniProtKB:Q8NFT6 xref: UniProtKB:Q8TEX0 xref: UniProtKB:Q96B19 xref: UniProtKB:Q9H912 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007444 ! DBF4B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0033512 name: RBG1L_HUMAN def: "RAB GTPase-activating protein 1-like" [UniProtKB:Q5R372] xref: EMBL:AAH12094.1 xref: EMBL:AAH18630.2 xref: EMBL:AAH41888.1 xref: EMBL:AAQ76819.1 xref: EMBL:BAA32316.2 xref: EMBL:BAA77330.1 xref: EMBL:BAA77332.1 xref: EMBL:BAA77333.2 xref: EMBL:BAA77334.1 xref: EMBL:BAC04635.1 xref: EMBL:CAB41266.1 xref: EMBL:CAB76100.1 xref: EMBL:CAH70225.1 xref: EMBL:CAI16277.1 xref: EMBL:CAI16278.1 xref: EMBL:CAI16279.1 xref: EMBL:CAI16280.1 xref: EMBL:CAI16281.1 xref: EMBL:CAI18933.1 xref: EMBL:CAI18934.1 xref: EMBL:CAI18935.1 xref: EMBL:CAI18936.1 xref: EMBL:CAI18937.1 xref: EMBL:CAI20382.1 xref: EMBL:CAI20383.1 xref: EMBL:CAI20384.1 xref: EMBL:CAI22380.1 xref: EMBL:CAI22381.1 xref: EMBL:CAI22382.1 xref: EMBL:CAI22876.1 xref: EMBL:CAI22877.1 xref: EMBL:CAI22878.1 xref: EMBL:CAI22932.1 xref: EMBL:CAI22933.1 xref: EMBL:CAI22934.1 xref: EMBL:CAI22935.1 xref: EMBL:CAI23486.1 xref: EMBL:EAW90977.1 xref: EMBL:EAW90979.1 xref: UniProtKB:O75059 xref: UniProtKB:Q3ZTR8 xref: UniProtKB:Q5R369 xref: UniProtKB:Q5R372 xref: UniProtKB:Q8IVV0 xref: UniProtKB:Q8N921 xref: UniProtKB:Q8WV78 xref: UniProtKB:Q9NSP8 xref: UniProtKB:Q9UQ19 xref: UniProtKB:Q9UQP5 xref: UniProtKB:Q9Y6Y5 xref: UniProtKB:Q9Y6Y6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008651 ! RABGAP1L_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0069772 ! RBG1L_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0069773 ! RBG1L_HUMAN-Phosphothreonine471 relationship: transforms_into CCO:B0069774 ! RBG1L_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0069775 ! RBG1L_HUMAN-Phosphoserine490 [Term] id: CCO:B0033513 name: Q5JZA9_HUMAN def: "RAB GTPase activating protein 1-like" [UniProtKB:Q5JZA9] xref: EMBL:CAI20381.1 xref: EMBL:CAI22875.1 xref: EMBL:CAI23485.1 xref: UniProtKB:Q5JZA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008651 ! RABGAP1L_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0033514 name: SMAP2_HUMAN def: "Stromal membrane-associated protein 2" [UniProtKB:Q8WU79] synonym: "Stromal membrane-associated protein 1-like" EXACT [UniProtKB:Q8WU79] xref: EMBL:AAH14512.1 xref: EMBL:AAH21133.1 xref: EMBL:CAB61580.1 xref: EMBL:CAB70912.1 xref: EMBL:CAI19853.1 xref: EMBL:CAI19854.1 xref: EMBL:CAI19855.1 xref: UniProtKB:Q5QPL2 xref: UniProtKB:Q8WU79 xref: UniProtKB:Q96C93 xref: UniProtKB:Q9NST2 xref: UniProtKB:Q9UJL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008188 ! SMAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0035665 ! SMAP2_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0035666 ! SMAP2_HUMAN-Phosphoserine240 [Term] id: CCO:B0033567 name: GHRL_HUMAN def: "Appetite-regulating hormone precursor" [UniProtKB:Q9UBU3] synonym: "Growth hormone secretagogue" EXACT [UniProtKB:Q9UBU3] synonym: "Growth hormone-releasing peptide" EXACT [UniProtKB:Q9UBU3] synonym: "M46 protein" EXACT [UniProtKB:Q9UBU3] synonym: "Motilin-related peptide" EXACT [UniProtKB:Q9UBU3] xref: EMBL:AAG10300.1 xref: EMBL:AAH25791.1 xref: EMBL:AAQ89412.1 xref: EMBL:BAA89371.1 xref: EMBL:BAB19045.1 xref: EMBL:CAB65733.1 xref: UniProtKB:Q8TAT9 xref: UniProtKB:Q9H3R3 xref: UniProtKB:Q9UBU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007591 ! GHRL_human relationship: has_function CCO:F0000196 ! G-protein-coupled receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0003214 ! growth hormone-releasing hormone activity relationship: has_function CCO:F0004383 ! protein tyrosine kinase activator activity relationship: has_function CCO:F0004781 ! ghrelin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001004 ! axon relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: participates_in CCO:P0001532 ! positive regulation of insulin secretion relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002100 ! negative regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002350 ! negative regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002733 ! negative regulation of insulin secretion relationship: participates_in CCO:P0003168 ! positive regulation of synaptogenesis relationship: transforms_into CCO:B0034837 ! GHRL_HUMAN-Leucine amide98 [Term] id: CCO:B0033592 name: PPIC_HUMAN def: "Peptidyl-prolyl cis-trans isomerase C" [UniProtKB:P45877] synonym: "Cyclophilin C" EXACT [UniProtKB:P45877] synonym: "EC 5.2.1.8" EXACT [UniProtKB:P45877] synonym: "PPIase" EXACT [UniProtKB:P45877] synonym: "Rotamase" EXACT [UniProtKB:P45877] xref: EMBL:AAB31350.1 xref: EMBL:AAH02678.1 xref: UniProtKB:P45877 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008002 ! PPIC_human relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0003031 ! cyclosporin A binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0005639 ! peptide binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017537 ! ppic-ubqln4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0033616 name: A8MV94_HUMAN xref: UniProtKB:A8MV94 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0033618 name: Q2TAM6_HUMAN def: "RUNX1 protein" [UniProtKB:Q2TAM6] xref: EMBL:AAI10829.1 xref: UniProtKB:Q2TAM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008137 ! RUNX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0033619 name: RUNX1_HUMAN def: "Runt-related transcription factor 1" [UniProtKB:Q01196] synonym: "Acute myeloid leukemia 1 protein" EXACT [UniProtKB:Q01196] synonym: "CBF-alpha-2" EXACT [UniProtKB:Q01196] synonym: "Core-binding factor subunit alpha-2" EXACT [UniProtKB:Q01196] synonym: "Oncogene AML-1" EXACT [UniProtKB:Q01196] synonym: "PEA2-alpha B" EXACT [UniProtKB:Q01196] synonym: "PEBP2-alpha B" EXACT [UniProtKB:Q01196] synonym: "Polyomavirus enhancer-binding protein 2 alpha B subunit" EXACT [UniProtKB:Q01196] synonym: "SL3-3 enhancer factor 1 alpha B subunit" EXACT [UniProtKB:Q01196] synonym: "SL3/AKV core-binding factor alpha B subunit" EXACT [UniProtKB:Q01196] xref: EMBL:AAA03086.1 xref: EMBL:AAA51720.1 xref: EMBL:AAB29907.1 xref: EMBL:AAB33729.1 xref: EMBL:AAB33730.1 xref: EMBL:AAB33731.1 xref: EMBL:AAB34819.2 xref: EMBL:AAB34820.2 xref: EMBL:AAB51691.1 xref: EMBL:AAC05246.1 xref: EMBL:AAC05247.1 xref: EMBL:BAA01426.1 xref: EMBL:BAA03089.1 xref: EMBL:BAA03559.1 xref: EMBL:BAA03560.1 xref: EMBL:BAA07902.1 xref: EMBL:BAA07903.1 xref: EMBL:BAA07904.1 xref: EMBL:BAA14020.1 xref: EMBL:BAA14021.1 xref: EMBL:BAA14022.1 xref: EMBL:CAA13070.1 xref: EMBL:CAA56092.1 xref: EMBL:CAA62464.1 xref: EMBL:CAA62466.1 xref: UniProtKB:A8MV94 xref: UniProtKB:O60472 xref: UniProtKB:O60473 xref: UniProtKB:O76047 xref: UniProtKB:O76089 xref: UniProtKB:Q01196 xref: UniProtKB:Q13081 xref: UniProtKB:Q13755 xref: UniProtKB:Q13756 xref: UniProtKB:Q13757 xref: UniProtKB:Q13758 xref: UniProtKB:Q13759 xref: UniProtKB:Q15341 xref: UniProtKB:Q15343 xref: UniProtKB:Q16122 xref: UniProtKB:Q16284 xref: UniProtKB:Q16285 xref: UniProtKB:Q16286 xref: UniProtKB:Q16346 xref: UniProtKB:Q16347 xref: UniProtKB:Q92479 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008137 ! RUNX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018090 ! nerf2-aml1-2 physical interaction relationship: participates_in CCO:I0018091 ! mef-aml1-1 physical interaction relationship: participates_in CCO:I0018372 ! nerf2-aml1-1 direct interaction relationship: participates_in CCO:I0019319 ! cbfb-runx1-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001341 ! positive regulation of granulocyte differentiation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0035609 ! RUNX1_HUMAN-Phosphothreonine14 relationship: transforms_into CCO:B0035610 ! RUNX1_HUMAN-Phosphoserine21 [Term] id: CCO:B0033620 name: Q5T802_HUMAN def: "Runt-related transcription factor 2" [UniProtKB:Q5T802] xref: EMBL:CAI13532.1 xref: EMBL:CAI19641.1 xref: EMBL:CAI19932.1 xref: UniProtKB:Q5T802 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008138 ! RUNX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0033622 name: RUNX2_HUMAN def: "Runt-related transcription factor 2" [UniProtKB:Q13950] synonym: "Acute myeloid leukemia 3 protein" EXACT [UniProtKB:Q13950] synonym: "CBF-alpha-1" EXACT [UniProtKB:Q13950] synonym: "Core-binding factor subunit alpha-1" EXACT [UniProtKB:Q13950] synonym: "Oncogene AML-3" EXACT [UniProtKB:Q13950] synonym: "OSF-2" EXACT [UniProtKB:Q13950] synonym: "Osteoblast-specific transcription factor 2" EXACT [UniProtKB:Q13950] synonym: "PEA2-alpha A" EXACT [UniProtKB:Q13950] synonym: "PEBP2-alpha A" EXACT [UniProtKB:Q13950] synonym: "Polyomavirus enhancer-binding protein 2 alpha A subunit" EXACT [UniProtKB:Q13950] synonym: "SL3-3 enhancer factor 1 alpha A subunit" EXACT [UniProtKB:Q13950] synonym: "SL3/AKV core-binding factor alpha A subunit" EXACT [UniProtKB:Q13950] xref: EMBL:AAA89072.1 xref: EMBL:AAB65158.1 xref: EMBL:AAB65159.2 xref: EMBL:AAC77441.1 xref: EMBL:AAC78624.1 xref: EMBL:CAI13528.1 xref: EMBL:CAI13531.1 xref: EMBL:CAI19638.1 xref: EMBL:CAI19639.1 xref: EMBL:CAI19925.1 xref: EMBL:CAI19931.1 xref: UniProtKB:O14614 xref: UniProtKB:O14615 xref: UniProtKB:O95181 xref: UniProtKB:Q13950 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008138 ! RUNX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018094 ! smad6-runx2-3 physical interaction relationship: participates_in CCO:I0018238 ! smad6-runx2 physical interaction relationship: participates_in CCO:I0018239 ! smurf-runx2 physical interaction relationship: participates_in CCO:I0018240 ! smad6-runx2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0033633 name: RL13_HUMAN def: "60S ribosomal protein L13" [UniProtKB:P26373] synonym: "Breast basic conserved protein 1" EXACT [UniProtKB:P26373] xref: EMBL:AAH04954.1 xref: EMBL:AAH07345.1 xref: EMBL:AAH07563.1 xref: EMBL:AAH07805.1 xref: EMBL:AAH10994.1 xref: EMBL:AAH13078.1 xref: EMBL:AAH14167.1 xref: EMBL:AAH20804.1 xref: EMBL:AAH27463.1 xref: EMBL:AAH63378.1 xref: EMBL:AAI06059.1 xref: EMBL:BAB93479.1 xref: EMBL:CAA45963.1 xref: UniProtKB:P26373 xref: UniProtKB:Q3KQT8 xref: UniProtKB:Q9BPX0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008109 ! RPL13_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002088 ! cytosolic ribosome relationship: participates_in CCO:I0016649 ! map3k1-rpl13 physical interaction relationship: participates_in CCO:I0016831 ! nfkb2-rpl13 physical interaction relationship: participates_in CCO:I0016980 ! tbk1-rpl13 physical interaction [Term] id: CCO:B0033689 name: Q8TD27_HUMAN def: "Ferritin" [UniProtKB:Q8TD27] xref: EMBL:AAK55486.1 xref: UniProtKB:Q8TD27 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001778 ! ferric iron binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0033704 name: FRIH_HUMAN def: "Ferritin heavy chain" [UniProtKB:P02794] synonym: "Cell proliferation-inducing gene 15 protein" EXACT [UniProtKB:P02794] synonym: "EC 1.16.3.1" EXACT [UniProtKB:P02794] synonym: "Ferritin H subunit" EXACT [UniProtKB:P02794] xref: EMBL:AAA35830.1 xref: EMBL:AAA35832.1 xref: EMBL:AAA35833.1 xref: EMBL:AAA52437.1 xref: EMBL:AAA52438.1 xref: EMBL:AAA52479.1 xref: EMBL:AAF89523.1 xref: EMBL:AAH00857.1 xref: EMBL:AAH01399.1 xref: EMBL:AAH11359.1 xref: EMBL:AAH13724.1 xref: EMBL:AAH15156.1 xref: EMBL:AAH16009.1 xref: EMBL:AAH16857.1 xref: EMBL:AAH63514.1 xref: EMBL:AAH66961.1 xref: EMBL:AAH73750.1 xref: EMBL:AAI04644.1 xref: EMBL:AAI05803.1 xref: EMBL:AAP82230.1 xref: EMBL:ABF47097.1 xref: EMBL:BAB93489.1 xref: EMBL:CAA25086.1 xref: EMBL:CAA27205.1 xref: UniProtKB:P02794 xref: UniProtKB:Q3KRA8 xref: UniProtKB:Q3SWW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007558 ! FTH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015700 ! fth1-ftl physical interaction relationship: participates_in CCO:I0019720 ! fth1-crmp1 physical interaction relationship: participates_in CCO:I0019721 ! fth1-ubr1 physical interaction relationship: participates_in CCO:I0019725 ! golph2-fth1 physical interaction relationship: participates_in CCO:I0019985 ! ell3-fth1 physical interaction relationship: participates_in CCO:I0020005 ! ftl-fth1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0034814 ! FRIH_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0066278 ! FRIH_HUMAN-Phosphoserine183 [Term] id: CCO:B0033733 name: MAFB_HUMAN def: "Transcription factor MafB" [UniProtKB:Q9Y5Q3] synonym: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog B" EXACT [UniProtKB:Q9Y5Q3] xref: EMBL:AAD30106.1 xref: EMBL:AAH28098.1 xref: EMBL:AAH36689.1 xref: EMBL:CAB75863.1 xref: UniProtKB:Q9H1F1 xref: UniProtKB:Q9Y5Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007811 ! MAFB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002461 ! negative regulation of erythrocyte differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0033734 name: MAF_HUMAN def: "Transcription factor Maf" [UniProtKB:O75444] synonym: "Proto-oncogene c-maf" EXACT [UniProtKB:O75444] xref: EMBL:AAC27037.1 xref: EMBL:AAC27038.1 xref: EMBL:AAC27039.1 xref: UniProtKB:O75444 xref: UniProtKB:Q9UP93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007812 ! MAF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0033778 name: SODM_HUMAN def: "Superoxide dismutase [Mn], mitochondrial precursor" [UniProtKB:P04179] synonym: "EC 1.15.1.1" EXACT [UniProtKB:P04179] xref: EMBL:AAA36622.1 xref: EMBL:AAD14248.1 xref: EMBL:AAH12423.1 xref: EMBL:AAP03428.1 xref: EMBL:AAP35613.1 xref: EMBL:CAA30687.1 xref: EMBL:CAA32502.1 xref: EMBL:CAA33228.1 xref: EMBL:CAA42066.1 xref: EMBL:CAA68533.1 xref: EMBL:CAA68791.1 xref: EMBL:CAI21845.1 xref: UniProtKB:P04179 xref: UniProtKB:P78434 xref: UniProtKB:Q16792 xref: UniProtKB:Q5TCM1 xref: UniProtKB:Q96EE6 xref: UniProtKB:Q9P2Z3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008197 ! SOD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020156 ! rps3a-sod2 physical interaction relationship: participates_in CCO:I0020368 ! mgc3731-sod2 physical interaction relationship: participates_in CCO:I0020523 ! c7orf20-sod2 physical interaction relationship: participates_in CCO:I0020645 ! rab4a-sod2 physical interaction relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0035672 ! SODM_HUMAN-N6-acetyllysine68 relationship: transforms_into CCO:B0070719 ! SODM_HUMAN-Nitrated tyrosine58 [Term] id: CCO:B0033797 name: Q548C9_HUMAN def: "Septin" [UniProtKB:Q548C9] xref: EMBL:AAN76547.1 xref: EMBL:BAF83666.1 xref: EMBL:CAI41425.1 xref: EMBL:EAW89855.1 xref: UniProtKB:Q548C9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005589 ! SEPT6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0033798 name: Q541S4_HUMAN def: "Septin" [UniProtKB:Q541S4] xref: EMBL:AAF97496.1 xref: EMBL:AAK61492.1 xref: EMBL:BAG61293.1 xref: EMBL:CAI41428.1 xref: EMBL:EAW89854.1 xref: UniProtKB:Q541S4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005589 ! SEPT6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0033823 name: BACH_HUMAN def: "Cytosolic acyl coenzyme A thioester hydrolase" [UniProtKB:O00154] synonym: "Acyl-CoA thioesterase 7" EXACT [UniProtKB:O00154] synonym: "Brain acyl-CoA hydrolase" EXACT [UniProtKB:O00154] synonym: "CTE-II" EXACT [UniProtKB:O00154] synonym: "CTE-IIa" EXACT [UniProtKB:O00154] synonym: "EC 3.1.2.2" EXACT [UniProtKB:O00154] synonym: "Long chain acyl-CoA thioester hydrolase" EXACT [UniProtKB:O00154] xref: EMBL:AAB61211.1 xref: EMBL:AAH17365.2 xref: EMBL:AAP35534.1 xref: EMBL:BAA24350.1 xref: EMBL:BAC20174.1 xref: EMBL:BAC20175.1 xref: EMBL:BAC20176.1 xref: EMBL:BAC20177.1 xref: EMBL:BAC20178.1 xref: EMBL:CAI19435.1 xref: EMBL:CAI19440.1 xref: EMBL:CAI19442.1 xref: EMBL:CAI19443.1 xref: EMBL:CAI19774.1 xref: EMBL:CAI19777.1 xref: EMBL:CAI19778.1 xref: EMBL:CAI19779.1 xref: UniProtKB:O00154 xref: UniProtKB:O43703 xref: UniProtKB:Q53Y78 xref: UniProtKB:Q5JYL2 xref: UniProtKB:Q5JYL3 xref: UniProtKB:Q5JYL4 xref: UniProtKB:Q5JYL5 xref: UniProtKB:Q5JYL6 xref: UniProtKB:Q5TGR4 xref: UniProtKB:Q9UJM9 xref: UniProtKB:Q9Y539 xref: UniProtKB:Q9Y540 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007300 ! ACOT7_human relationship: has_function CCO:F0000016 ! acyl-CoA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000566 ! carboxylesterase activity relationship: has_function CCO:F0003106 ! palmitoyl-CoA hydrolase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0019085 ! atxn1-acot7 physical interaction [Term] id: CCO:B0033870 name: GAGE5_HUMAN def: "G antigen 5" [UniProtKB:Q13069] synonym: "Cancer/testis antigen 4.5" EXACT [UniProtKB:Q13069] synonym: "CT4.5" EXACT [UniProtKB:Q13069] synonym: "GAGE-5" EXACT [UniProtKB:Q13069] xref: EMBL:AAA82748.1 xref: EMBL:AAH24914.1 xref: EMBL:CAG47032.1 xref: UniProtKB:Q13069 xref: UniProtKB:Q6FG72 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007579 ! GAGE5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015200 ! gage5-gmcl1l physical interaction [Term] id: CCO:B0033871 name: GAGE8_HUMAN def: "G antigen 8" [UniProtKB:Q9UEU5] synonym: "Cancer/testis antigen 4.8" EXACT [UniProtKB:Q9UEU5] synonym: "CT4.8" EXACT [UniProtKB:Q9UEU5] synonym: "GAGE-8" EXACT [UniProtKB:Q9UEU5] xref: EMBL:AAC33676.1 xref: EMBL:AAH18052.1 xref: EMBL:CAI95422.1 xref: UniProtKB:A6NG46 xref: UniProtKB:A6NNR8 xref: UniProtKB:Q4V325 xref: UniProtKB:Q9UEU5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007582 ! GAGE8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015757 ! gage8-gmcl1l physical interaction relationship: participates_in CCO:I0019411 ! gage8-gmcl1l-1 physical interaction [Term] id: CCO:B0033902 name: Q5TA42_HUMAN def: "Centaurin, beta 5 (Centaurin, beta 5, isoform CRA_c)" [UniProtKB:Q5TA42] xref: EMBL:CAI23171.1 xref: EMBL:CAI23244.1 xref: EMBL:EAW56248.1 xref: UniProtKB:Q5TA42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008671 ! CENTB5_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0033903 name: CENB1_HUMAN def: "Centaurin-beta-1" [UniProtKB:Q15027] synonym: "ACAP1" EXACT [UniProtKB:Q15027] synonym: "ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 1" EXACT [UniProtKB:Q15027] synonym: "Cnt-b1" EXACT [UniProtKB:Q15027] xref: EMBL:AAH18543.1 xref: EMBL:AAP88790.1 xref: EMBL:BAA06418.2 xref: UniProtKB:Q15027 xref: UniProtKB:Q53XN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007380 ! CENTB1_human relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0034644 ! CENB1_HUMAN-Nitrated tyrosine485 relationship: transforms_into CCO:B0034645 ! CENB1_HUMAN-Phosphoserine554 [Term] id: CCO:B0033904 name: CENB2_HUMAN def: "Centaurin-beta-2" [UniProtKB:Q15057] synonym: "ACAP2" EXACT [UniProtKB:Q15057] synonym: "ARFGAP with coiled-coil, ANK repeat and PH domain-containing protein 2" EXACT [UniProtKB:Q15057] synonym: "Cnt-b2" EXACT [UniProtKB:Q15057] xref: EMBL:AAH31005.1 xref: EMBL:AAH60767.1 xref: EMBL:BAA05064.2 xref: EMBL:CAB41450.1 xref: UniProtKB:Q15057 xref: UniProtKB:Q8N5Z8 xref: UniProtKB:Q9UQR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007381 ! CENTB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0034646 ! CENB2_HUMAN-Phosphoserine521 relationship: transforms_into CCO:B0034647 ! CENB2_HUMAN-Phosphotyrosine742 relationship: transforms_into CCO:B0034648 ! CENB2_HUMAN-Phosphotyrosine750 relationship: transforms_into CCO:B0034649 ! CENB2_HUMAN-Phosphoserine775 relationship: transforms_into CCO:B0064257 ! CENB2_HUMAN-Phosphoserine379 relationship: transforms_into CCO:B0064258 ! CENB2_HUMAN-Phosphoserine384 [Term] id: CCO:B0033965 name: CTLF6_HUMAN def: "Centaurin-gamma-like family member 6" [UniProtKB:Q5VTM2] xref: EMBL:CAH72201.1 xref: UniProtKB:Q5VTM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007442 ! CTGLF6_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0033967 name: CTLF5_HUMAN def: "Centaurin-gamma-like family member 5" [UniProtKB:Q5SRD3] xref: EMBL:CAI16094.1 xref: UniProtKB:Q5SRD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007441 ! CTGLF5_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0033969 name: CTLF4_HUMAN def: "Centaurin-gamma-like family member 4" [UniProtKB:Q5VUJ5] xref: EMBL:CAH70062.1 xref: UniProtKB:A6NGH4 xref: UniProtKB:Q5VUJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007440 ! CTGLF4_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0033970 name: CTLF2_HUMAN def: "Centaurin-gamma-like family member 2" [UniProtKB:A6NIR3] xref: UniProtKB:A6NIR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008435 ! CTGLF2_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0033972 name: CTLF1_HUMAN def: "Centaurin-gamma-like family member 1" [UniProtKB:Q96P64] xref: EMBL:AAL10290.1 xref: UniProtKB:Q96P64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007438 ! CTGLF1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0033973 name: CTLF3_HUMAN def: "Centaurin-gamma-like family member 3" [UniProtKB:Q5VW22] xref: EMBL:CAH72489.1 xref: UniProtKB:Q5VW22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007439 ! CTGLF3_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0033974 name: Q86XV2_HUMAN def: "CTGLF1 protein" [UniProtKB:Q86XV2] xref: EMBL:AAH48341.1 xref: UniProtKB:Q86XV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007438 ! CTGLF1_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0034007 name: PSB7_HUMAN def: "Proteasome subunit beta type-7 precursor" [UniProtKB:Q99436] synonym: "EC 3.4.25.1" EXACT [UniProtKB:Q99436] synonym: "Macropain chain Z" EXACT [UniProtKB:Q99436] synonym: "Multicatalytic endopeptidase complex chain Z" EXACT [UniProtKB:Q99436] synonym: "Proteasome subunit Z" EXACT [UniProtKB:Q99436] xref: EMBL:AAH00509.1 xref: EMBL:AAH17116.2 xref: EMBL:BAA07238.1 xref: UniProtKB:Q96AG8 xref: UniProtKB:Q99436 xref: UniProtKB:Q9BWA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008024 ! PSMB7_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008742 ! beta1-beta7 physical interaction relationship: participates_in CCO:I0008745 ! beta1i-beta7 physical interaction relationship: participates_in CCO:I0008754 ! beta5-beta7 physical interaction relationship: participates_in CCO:I0008755 ! beta5i-beta7 physical interaction relationship: participates_in CCO:I0008756 ! beta6-beta7 physical interaction relationship: participates_in CCO:I0008757 ! beta7-beta3 physical interaction relationship: participates_in CCO:I0008758 ! beta7-beta7 physical interaction relationship: participates_in CCO:I0008759 ! beta7-beta5i physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:I0008818 ! c2f-psmb7 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0035481 ! PSB7_HUMAN-Phosphotyrosine154 [Term] id: CCO:B0034023 name: S26A5_HUMAN def: "Prestin" [UniProtKB:P58743] synonym: "Solute carrier family 26 member 5" EXACT [UniProtKB:P58743] xref: EMBL:AAP31417.1 xref: EMBL:AAP31532.1 xref: EMBL:AAP31533.1 xref: EMBL:AAP31534.1 xref: UniProtKB:P58743 xref: UniProtKB:Q86UF8 xref: UniProtKB:Q86UF9 xref: UniProtKB:Q86UG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008153 ! SLC26A5_human relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001811 ! secondary active sulfate transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000822 ! regulation of cell shape [Term] id: CCO:B0034060 name: FABP7_HUMAN def: "Fatty acid-binding protein, brain" [UniProtKB:O15540] synonym: "B-FABP" EXACT [UniProtKB:O15540] synonym: "BLBP" EXACT [UniProtKB:O15540] synonym: "Brain lipid-binding protein" EXACT [UniProtKB:O15540] synonym: "Fatty acid-binding protein 7" EXACT [UniProtKB:O15540] synonym: "Mammary-derived growth inhibitor related" EXACT [UniProtKB:O15540] xref: EMBL:AAB87141.1 xref: EMBL:AAD00507.1 xref: EMBL:AAH12299.1 xref: EMBL:BAA23324.1 xref: EMBL:BAA23645.1 xref: EMBL:CAA05773.1 xref: EMBL:CAG33338.1 xref: EMBL:CAI15449.1 xref: UniProtKB:O14951 xref: UniProtKB:O15540 xref: UniProtKB:Q6IAU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007521 ! FABP7_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0034782 ! FABP7_HUMAN-N-acetylvaline2 [Term] id: CCO:B0034068 name: FABP4_HUMAN def: "Fatty acid-binding protein, adipocyte" [UniProtKB:P15090] synonym: "A-FABP" EXACT [UniProtKB:P15090] synonym: "Adipocyte lipid-binding protein" EXACT [UniProtKB:P15090] synonym: "AFABP" EXACT [UniProtKB:P15090] synonym: "ALBP" EXACT [UniProtKB:P15090] synonym: "Fatty acid-binding protein 4" EXACT [UniProtKB:P15090] xref: EMBL:AAA51689.1 xref: EMBL:AAH03672.1 xref: EMBL:AAP35455.1 xref: UniProtKB:P15090 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007519 ! FABP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019993 ! fabp4-vim physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0034779 ! FABP4_HUMAN-Phosphotyrosine20 [Term] id: CCO:B0034070 name: FABPH_HUMAN def: "Fatty acid-binding protein, heart" [UniProtKB:P05413] synonym: "H-FABP" EXACT [UniProtKB:P05413] synonym: "Heart-type fatty acid-binding protein" EXACT [UniProtKB:P05413] synonym: "M-FABP" EXACT [UniProtKB:P05413] synonym: "Mammary-derived growth inhibitor" EXACT [UniProtKB:P05413] synonym: "MDGI" EXACT [UniProtKB:P05413] synonym: "Muscle fatty acid-binding protein" EXACT [UniProtKB:P05413] xref: EMBL:AAB02555.1 xref: EMBL:AAB29294.1 xref: EMBL:AAC99800.1 xref: EMBL:AAH07021.1 xref: EMBL:AAP35373.1 xref: EMBL:CAA39889.1 xref: EMBL:CAA71305.1 xref: EMBL:CAH71850.1 xref: UniProtKB:P05413 xref: UniProtKB:Q5VV93 xref: UniProtKB:Q99957 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007523 ! FABP3_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020686 ! vps28-fabp3 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0034783 ! FABPH_HUMAN-N-acetylvaline2 relationship: transforms_into CCO:B0034784 ! FABPH_HUMAN-Phosphotyrosine20 [Term] id: CCO:B0034076 name: RABP1_HUMAN def: "Cellular retinoic acid-binding protein 1" [UniProtKB:P29762] synonym: "Cellular retinoic acid-binding protein I" EXACT [UniProtKB:P29762] synonym: "CRABP-I" EXACT [UniProtKB:P29762] xref: EMBL:AAB20773.1 xref: EMBL:AAH22069.1 xref: EMBL:CAG33298.1 xref: UniProtKB:P29762 xref: UniProtKB:Q6IAY7 xref: UniProtKB:Q8WTV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008049 ! CRABP1_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001639 ! retinoid binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003468 ! retinal binding relationship: has_function CCO:F0004190 ! retinol binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020595 ! mpp3-crabp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0034087 name: NED4L_HUMAN def: "E3 ubiquitin-protein ligase NEDD4-like protein" [UniProtKB:Q96PU5] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q96PU5] synonym: "Nedd4-2" EXACT [UniProtKB:Q96PU5] synonym: "NEDD4.2" EXACT [UniProtKB:Q96PU5] xref: EMBL:AAG43524.1 xref: EMBL:AAH00621.2 xref: EMBL:AAH19345.1 xref: EMBL:AAH32597.1 xref: EMBL:AAM46208.1 xref: EMBL:AAM76728.1 xref: EMBL:AAM76729.1 xref: EMBL:AAM76730.1 xref: EMBL:AAP75706.1 xref: EMBL:BAA23711.1 xref: EMBL:BAB69424.1 xref: EMBL:CAB70754.1 xref: UniProtKB:O43165 xref: UniProtKB:Q7Z5F1 xref: UniProtKB:Q7Z5F2 xref: UniProtKB:Q7Z5N3 xref: UniProtKB:Q8N5A7 xref: UniProtKB:Q8WUU9 xref: UniProtKB:Q96PU5 xref: UniProtKB:Q9BW58 xref: UniProtKB:Q9H2W4 xref: UniProtKB:Q9NT88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007869 ! NEDD4L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020235 ! arhgdia-nedd4l physical interaction relationship: participates_in CCO:P0002557 ! positive regulation of endocytosis relationship: transforms_into CCO:B0035249 ! NED4L_HUMAN-Phosphothreonine302 relationship: transforms_into CCO:B0035250 ! NED4L_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0035251 ! NED4L_HUMAN-Phosphothreonine367 relationship: transforms_into CCO:B0035252 ! NED4L_HUMAN-Phosphoserine446 relationship: transforms_into CCO:B0035253 ! NED4L_HUMAN-Phosphoserine448 relationship: transforms_into CCO:B0035254 ! NED4L_HUMAN-Phosphoserine479 relationship: transforms_into CCO:B0035255 ! NED4L_HUMAN-Phosphoserine483 relationship: transforms_into CCO:B0035256 ! NED4L_HUMAN-Phosphoserine487 relationship: transforms_into CCO:B0068558 ! NED4L_HUMAN-Phosphothreonine318 relationship: transforms_into CCO:B0068559 ! NED4L_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0068560 ! NED4L_HUMAN-Phosphoserine464 [Term] id: CCO:B0034094 name: RHG28_HUMAN def: "Rho GTPase-activating protein 28" [UniProtKB:Q9P2N2] synonym: "Rho-type GTPase-activating protein 28" EXACT [UniProtKB:Q9P2N2] xref: EMBL:AAH33668.1 xref: EMBL:AAH65274.1 xref: EMBL:BAA91533.1 xref: EMBL:BAA92552.1 xref: UniProtKB:Q6P160 xref: UniProtKB:Q8N4T3 xref: UniProtKB:Q9NW53 xref: UniProtKB:Q9P2N2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008102 ! ARHGAP28_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0035577 ! RHG28_HUMAN-Phosphothreonine155 relationship: transforms_into CCO:B0035578 ! RHG28_HUMAN-Phosphothreonine157 relationship: transforms_into CCO:B0035579 ! RHG28_HUMAN-Phosphothreonine159 [Term] id: CCO:B0034095 name: A8MQB7_HUMAN def: "Putative uncharacterized protein ARHGAP28" [UniProtKB:A8MQB7] xref: UniProtKB:A8MQB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008102 ! ARHGAP28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0034099 name: A8MU88_HUMAN def: "Putative uncharacterized protein ARHGAP28" [UniProtKB:A8MU88] xref: UniProtKB:A8MU88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008102 ! ARHGAP28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0034104 name: K6PL_HUMAN def: "6-phosphofructokinase, liver type" [UniProtKB:P17858] synonym: "EC 2.7.1.11" EXACT [UniProtKB:P17858] synonym: "PFK-B" EXACT [UniProtKB:P17858] synonym: "Phosphofructo-1-kinase isozyme B" EXACT [UniProtKB:P17858] synonym: "Phosphofructokinase 1" EXACT [UniProtKB:P17858] synonym: "Phosphohexokinase" EXACT [UniProtKB:P17858] xref: EMBL:AAH06422.1 xref: EMBL:AAH07536.1 xref: EMBL:AAH08964.1 xref: EMBL:AAH09919.1 xref: EMBL:BAA95561.1 xref: EMBL:CAA33597.1 xref: EMBL:CAB46744.1 xref: UniProtKB:P17858 xref: UniProtKB:Q96A64 xref: UniProtKB:Q96IH4 xref: UniProtKB:Q9BR91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007710 ! PFKL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015330 ! krtap4_12-pfkl physical interaction relationship: participates_in CCO:I0018010 ! pfkl-pfkm-4 physical interaction relationship: participates_in CCO:I0018011 ! pfkl-pfkm-5 physical interaction relationship: participates_in CCO:I0018307 ! pfkl-pfkm-1 physical interaction relationship: participates_in CCO:I0018308 ! pfkl-pfkm-2 physical interaction relationship: participates_in CCO:I0018309 ! pfkl-pfkm-3 physical interaction relationship: participates_in CCO:I0018928 ! atn1-pfkl physical interaction relationship: participates_in CCO:I0019435 ! pfkm-pfkl3_human physical interaction relationship: participates_in CCO:I0019436 ! pfkm2-pfkl2_human physical interaction relationship: participates_in CCO:I0019437 ! pfkm3-pfkl1_human physical interaction relationship: participates_in CCO:I0020104 ! pfkl-cops6 physical interaction relationship: participates_in CCO:P0000623 ! regulation of glycolysis relationship: transforms_into CCO:B0034954 ! K6PL_HUMAN-Phosphotyrosine633 relationship: transforms_into CCO:B0034955 ! K6PL_HUMAN-Phosphotyrosine640 [Term] id: CCO:B0034112 name: K6PF_HUMAN def: "6-phosphofructokinase, muscle type" [UniProtKB:P08237] synonym: "EC 2.7.1.11" EXACT [UniProtKB:P08237] synonym: "PFK-A" EXACT [UniProtKB:P08237] synonym: "Phosphofructo-1-kinase isozyme A" EXACT [UniProtKB:P08237] synonym: "Phosphofructokinase 1" EXACT [UniProtKB:P08237] synonym: "Phosphofructokinase-M" EXACT [UniProtKB:P08237] synonym: "Phosphohexokinase" EXACT [UniProtKB:P08237] xref: EMBL:AAA36436.1 xref: EMBL:AAA60068.1 xref: EMBL:AAA79220.1 xref: EMBL:AAA82938.1 xref: EMBL:AAH00534.1 xref: EMBL:AAH12799.1 xref: EMBL:AAH13298.1 xref: EMBL:AAH21203.1 xref: EMBL:CAA68692.1 xref: UniProtKB:P08237 xref: UniProtKB:Q16814 xref: UniProtKB:Q16815 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007709 ! PFKM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018010 ! pfkl-pfkm-4 physical interaction relationship: participates_in CCO:I0018011 ! pfkl-pfkm-5 physical interaction relationship: participates_in CCO:I0018307 ! pfkl-pfkm-1 physical interaction relationship: participates_in CCO:I0018308 ! pfkl-pfkm-2 physical interaction relationship: participates_in CCO:I0018309 ! pfkl-pfkm-3 physical interaction relationship: participates_in CCO:I0019435 ! pfkm-pfkl3_human physical interaction relationship: participates_in CCO:I0019436 ! pfkm2-pfkl2_human physical interaction relationship: participates_in CCO:I0019437 ! pfkm3-pfkl1_human physical interaction relationship: participates_in CCO:P0000623 ! regulation of glycolysis relationship: transforms_into CCO:B0034952 ! K6PF_HUMAN-Phosphothreonine2 relationship: transforms_into CCO:B0034953 ! K6PF_HUMAN-Phosphoserine775 [Term] id: CCO:B0034126 name: RARG_HUMAN def: "Retinoic acid receptor gamma" [UniProtKB:P13631] synonym: "Nuclear receptor subfamily 1 group B member 3" EXACT [UniProtKB:P13631] synonym: "RAR-gamma" EXACT [UniProtKB:P13631] xref: EMBL:AAA52692.1 xref: EMBL:AAA60253.1 xref: EMBL:AAA60254.1 xref: EMBL:AAA63254.1 xref: EMBL:AAG41594.2 xref: EMBL:AAG41595.1 xref: EMBL:AAH93727.1 xref: EMBL:AAH93729.1 xref: EMBL:CAA40548.1 xref: EMBL:CAB60726.1 xref: UniProtKB:P13631 xref: UniProtKB:P22932 xref: UniProtKB:Q15281 xref: UniProtKB:Q52LZ8 xref: UniProtKB:Q9BYX8 xref: UniProtKB:Q9H1I3 xref: UniProtKB:Q9UJ38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008058 ! RARG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006286 ! retinoid X receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002150 ! positive regulation of programmed cell death relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002838 ! retinoic acid receptor signaling pathway relationship: participates_in CCO:P0003241 ! Wnt receptor signaling pathway through beta-catenin [Term] id: CCO:B0034147 name: I12R2_HUMAN def: "Interleukin-12 receptor beta-2 chain precursor" [UniProtKB:Q99665] synonym: "IL-12 receptor beta-2" EXACT [UniProtKB:Q99665] synonym: "IL-12R-beta2" EXACT [UniProtKB:Q99665] xref: EMBL:AAB36675.1 xref: EMBL:AAI04773.1 xref: EMBL:AAI04775.1 xref: EMBL:AAT45456.1 xref: UniProtKB:Q2M3V3 xref: UniProtKB:Q99665 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007637 ! IL12RB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0034864 ! I12R2_HUMAN-Phosphotyrosine800 [Term] id: CCO:B0034159 name: AQP1_HUMAN def: "Aquaporin-1" [UniProtKB:P29972] synonym: "AQP-1" EXACT [UniProtKB:P29972] synonym: "Aquaporin-CHIP" EXACT [UniProtKB:P29972] synonym: "Urine water channel" EXACT [UniProtKB:P29972] synonym: "Water channel protein for red blood cells and kidney proximal tubule" EXACT [UniProtKB:P29972] xref: EMBL:AAA58425.1 xref: EMBL:AAB31193.1 xref: EMBL:AAC16481.1 xref: EMBL:AAC23788.1 xref: EMBL:AAC50648.1 xref: EMBL:AAC50649.1 xref: EMBL:AAH22486.1 xref: EMBL:AAL87136.1 xref: EMBL:AAX24129.1 xref: UniProtKB:P29972 xref: UniProtKB:Q8TBI5 xref: UniProtKB:Q8TDC1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007262 ! AQP1_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001597 ! water transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015168 ! aqp1-mdfi physical interaction relationship: participates_in CCO:I0015717 ! aqp1-trip6 physical interaction relationship: transforms_into CCO:B0034558 ! AQP1_HUMAN-Phosphothreonine246 relationship: transforms_into CCO:B0034559 ! AQP1_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0034560 ! AQP1_HUMAN-Phosphoserine262 [Term] id: CCO:B0034172 name: A9UF07_HUMAN def: "BCR/ABL fusion protein isoform Y5" [UniProtKB:A9UF07] xref: EMBL:ABX82713.1 xref: UniProtKB:A9UF07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008391 ! BCR/ABL fusion_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0034175 name: A9UF02_HUMAN def: "BCR/ABL fusion protein isoform X9" [UniProtKB:A9UF02] xref: EMBL:ABX82708.1 xref: UniProtKB:A9UF02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008391 ! BCR/ABL fusion_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0034177 name: Q14869_HUMAN def: "MSSP-2 protein" [UniProtKB:Q14869] xref: EMBL:CAA54628.1 xref: UniProtKB:Q14869 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008520 ! MSSP-2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0034185 name: Q969I2_HUMAN def: "TFG protein" [UniProtKB:Q969I2] synonym: "cDNA FLJ36137 fis, clone TESTI2024844, highly similar to Protein TFG" EXACT [UniProtKB:Q969I2] synonym: "TRK-fused" EXACT [UniProtKB:Q969I2] synonym: "TRK-fused gene" EXACT [UniProtKB:Q969I2] xref: EMBL:AAH01483.1 xref: EMBL:AAH09241.1 xref: EMBL:AAH23599.1 xref: EMBL:AAP36096.1 xref: EMBL:BAG52721.1 xref: EMBL:CAG33062.1 xref: EMBL:EAW79813.1 xref: UniProtKB:Q969I2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008284 ! TFG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016726 ! map3k3-q969i2 physical interaction [Term] id: CCO:B0034188 name: TFG_HUMAN def: "Protein TFG" [UniProtKB:Q92734] synonym: "TRK-fused gene protein" EXACT [UniProtKB:Q92734] xref: EMBL:CAA59936.1 xref: EMBL:CAA69264.1 xref: UniProtKB:Q15656 xref: UniProtKB:Q92734 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008284 ! TFG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0016702 ! map3k3-tfg physical interaction relationship: participates_in CCO:I0019848 ! tfg-crmp1 physical interaction relationship: participates_in CCO:I0019849 ! tfg-kiaa1377 physical interaction relationship: participates_in CCO:I0019850 ! tfg-tfg-2 physical interaction relationship: participates_in CCO:I0020190 ! tfg-c14orf1 physical interaction relationship: participates_in CCO:I0020191 ! tfg-gbp2 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0071372 ! TFG_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0071373 ! TFG_HUMAN-Phosphoserine197 [Term] id: CCO:B0034197 name: ABCA1_HUMAN def: "ATP-binding cassette sub-family A member 1" [UniProtKB:O95477] synonym: "ABC-1" EXACT [UniProtKB:O95477] synonym: "ATP-binding cassette 1" EXACT [UniProtKB:O95477] synonym: "ATP-binding cassette transporter 1" EXACT [UniProtKB:O95477] synonym: "Cholesterol efflux regulatory protein" EXACT [UniProtKB:O95477] xref: EMBL:AAD49849.1 xref: EMBL:AAD49851.1 xref: EMBL:AAD49852.1 xref: EMBL:AAD49853.1 xref: EMBL:AAD49854.1 xref: EMBL:AAF86276.1 xref: EMBL:AAF98175.1 xref: EMBL:AAK43526.1 xref: EMBL:BAB63210.1 xref: EMBL:CAA10005.1 xref: EMBL:CAH72444.1 xref: EMBL:CAH73579.1 xref: UniProtKB:O95477 xref: UniProtKB:Q5VX33 xref: UniProtKB:Q96S56 xref: UniProtKB:Q96T85 xref: UniProtKB:Q9NQV4 xref: UniProtKB:Q9UN06 xref: UniProtKB:Q9UN07 xref: UniProtKB:Q9UN08 xref: UniProtKB:Q9UN09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007203 ! ABCA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018347 ! abca1-utrn physical interaction relationship: participates_in CCO:I0018348 ! abca1-sntb1-1 physical interaction relationship: participates_in CCO:I0018349 ! abca1-snta1 physical interaction relationship: participates_in CCO:I0018350 ! abca1-dgl3 physical interaction relationship: participates_in CCO:I0018359 ! abca1-arhgef12 physical interaction relationship: participates_in CCO:I0018360 ! abca1-mpdz physical interaction relationship: participates_in CCO:I0018361 ! abca1-dig2 physical interaction relationship: participates_in CCO:I0018362 ! abca1-lin7b physical interaction relationship: participates_in CCO:I0018676 ! abca1-sntb1 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001312 ! positive regulation of cAMP biosynthetic process relationship: participates_in CCO:P0001634 ! Cdc42 protein signal transduction relationship: transforms_into CCO:B0034496 ! ABCA1_HUMAN-Phosphoserine1042 relationship: transforms_into CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: transforms_into CCO:B0034498 ! ABCA1_HUMAN-Phosphoserine1147 relationship: transforms_into CCO:B0034499 ! ABCA1_HUMAN-Phosphoserine2054 [Term] id: CCO:B0034258 name: GAS6_HUMAN def: "Growth arrest-specific protein 6 precursor" [UniProtKB:Q14393] synonym: "AXL receptor tyrosine kinase ligand" EXACT [UniProtKB:Q14393] synonym: "GAS-6" EXACT [UniProtKB:Q14393] xref: EMBL:AAA58494.1 xref: EMBL:AAH38984.1 xref: EMBL:AAO41859.1 xref: EMBL:AAO84057.1 xref: EMBL:ABR09277.1 xref: EMBL:BAC86580.1 xref: EMBL:BAF83492.1 xref: EMBL:CAH71174.1 xref: EMBL:DAA01155.1 xref: UniProtKB:Q14393 xref: UniProtKB:Q6IMN1 xref: UniProtKB:Q7Z7N3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007583 ! GAS6_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0034271 name: RS25_HUMAN def: "40S ribosomal protein S25" [UniProtKB:P62851] xref: EMBL:AAA16105.1 xref: EMBL:AAH03537.1 xref: EMBL:AAH04294.1 xref: EMBL:AAH04986.1 xref: EMBL:BAB79482.1 xref: UniProtKB:P25111 xref: UniProtKB:P62851 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008130 ! RPS25_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0034291 name: IGHG3_HUMAN def: "Ig gamma-3 chain C region" [UniProtKB:P01860] synonym: "HDC" EXACT [UniProtKB:P01860] synonym: "Heavy chain disease protein" EXACT [UniProtKB:P01860] xref: EMBL:AAA52805.1 xref: EMBL:CAA27268.1 xref: UniProtKB:A2NU35 xref: UniProtKB:P01860 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007666 ! IGHG3_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: participates_in CCO:I0016493 ! ikbkg-ighg3 physical interaction [Term] id: CCO:B0034304 name: Q8N4Y9_HUMAN def: "IGHG3 protein" [UniProtKB:Q8N4Y9] xref: EMBL:AAH33178.1 xref: UniProtKB:Q8N4Y9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007666 ! IGHG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016540 ! ikbkg-q8n4y9 physical interaction [Term] id: CCO:B0034311 name: Q86TT2_HUMAN def: "Full-length cDNA clone CS0DI019YF20 of Placenta of Homo sapiens (human)" [UniProtKB:Q86TT2] xref: EMBL:CAD62606.1 xref: UniProtKB:Q86TT2 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016539 ! ikbkg-q86tt2 physical interaction [Term] id: CCO:B0034317 name: IGHG1_HUMAN def: "Ig gamma-1 chain C region" [UniProtKB:P01857] xref: EMBL:AAC82527.1 xref: UniProtKB:P01857 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007664 ! IGHG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016537 ! ikbkg-ighg1 physical interaction relationship: participates_in CCO:I0017105 ! traf1-ighg1 physical interaction relationship: participates_in CCO:I0017709 ! ighg1-fcg2b-9 direct interaction relationship: participates_in CCO:I0017710 ! ighg1-fcg2b-10 direct interaction relationship: participates_in CCO:I0017711 ! ighg1-fcg2b-11 direct interaction relationship: participates_in CCO:I0017712 ! ighg1-fcg2b-12 direct interaction relationship: participates_in CCO:I0017713 ! ighg1-fcg2b-13 direct interaction relationship: participates_in CCO:I0017714 ! ighg1-fcg2b-14 direct interaction relationship: participates_in CCO:I0017715 ! ighg1-fcg2b-15 direct interaction relationship: participates_in CCO:I0017716 ! ighg1-fcg2b-16 direct interaction relationship: participates_in CCO:I0017717 ! ighg1-fcg2b-17 direct interaction relationship: participates_in CCO:I0017718 ! ighg1-fcg2b-18 direct interaction relationship: participates_in CCO:I0017720 ! ighg1-fcg2b-20 direct interaction relationship: participates_in CCO:I0017721 ! ighg1-fcg2b-21 direct interaction relationship: participates_in CCO:I0017722 ! ighg1-fcg2b-22 direct interaction relationship: participates_in CCO:I0017723 ! ighg1-fcg2b-23 direct interaction relationship: participates_in CCO:I0017724 ! ighg1-fcg2b-24 direct interaction relationship: participates_in CCO:I0017725 ! ighg1-fcg2b-25 direct interaction relationship: participates_in CCO:I0017726 ! ighg1-fcg2b-26 direct interaction relationship: participates_in CCO:I0017727 ! ighg1-fcg2b-27 direct interaction relationship: participates_in CCO:I0017728 ! ighg1-fcg2b-28 direct interaction relationship: participates_in CCO:I0017729 ! ighg1-fcg2b-29 direct interaction relationship: participates_in CCO:I0017730 ! ighg1-fcg2b-30 direct interaction relationship: participates_in CCO:I0017731 ! ighg1-fcg2b-31 direct interaction relationship: participates_in CCO:I0017736 ! ighg1-fcg2b-19 direct interaction relationship: participates_in CCO:I0017737 ! ighg1-fcg2b-8 direct interaction relationship: participates_in CCO:I0018219 ! ighg1-fcg2b-1 direct interaction relationship: participates_in CCO:I0018220 ! ighg1-fcg2b-2 direct interaction relationship: participates_in CCO:I0018221 ! ighg1-fcg2b-3 direct interaction relationship: participates_in CCO:I0018222 ! ighg1-fcg2b-4 direct interaction relationship: participates_in CCO:I0018223 ! ighg1-fcg2b-5 direct interaction relationship: participates_in CCO:I0018224 ! ighg1-fcg2b-6 direct interaction relationship: participates_in CCO:I0018225 ! ighg1-fcg2b-7 direct interaction [Term] id: CCO:B0034353 name: SET1B_HUMAN def: "Histone-lysine N-methyltransferase SETD1B" [UniProtKB:Q9UPS6] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9UPS6] synonym: "hSET1B" EXACT [UniProtKB:Q9UPS6] synonym: "Lysine N-methyltransferase 2G" EXACT [UniProtKB:Q9UPS6] synonym: "SET domain-containing protein 1B" EXACT [UniProtKB:Q9UPS6] xref: EMBL:BAA83028.1 xref: UniProtKB:Q9UPS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008174 ! SETD1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0035630 ! SET1B_HUMAN-Phosphoserine1616 relationship: transforms_into CCO:B0035631 ! SET1B_HUMAN-Phosphoserine1620 [Term] id: CCO:B0034496 name: ABCA1_HUMAN-Phosphoserine1042 def: "Protein ABCA1_HUMAN with the residue 1042 substituted with Phosphoserine" [UniProtKB:O95477] comment: by PKA; xref: UniProtKB:O95477 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034197 ! ABCA1_HUMAN [Term] id: CCO:B0034497 name: ABCA1_HUMAN-Phosphoserine1141 def: "Protein ABCA1_HUMAN with the residue 1141 substituted with Phosphoserine" [UniProtKB:O95477] comment: By similarity xref: UniProtKB:O95477 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001671 ! phospholipid transporter activity relationship: has_function CCO:F0001962 ! anion transmembrane transporter activity relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0003584 ! cholesterol transporter activity relationship: has_function CCO:F0004349 ! apolipoprotein receptor activity relationship: has_function CCO:F0004403 ! syntaxin-13 binding relationship: has_function CCO:F0004648 ! small GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: located_in CCO:C0001950 ! phagocytic vesicle relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0034197 ! ABCA1_HUMAN [Term] id: CCO:B0034498 name: ABCA1_HUMAN-Phosphoserine1147 def: "Protein ABCA1_HUMAN with the residue 1147 substituted with Phosphoserine" [UniProtKB:O95477] comment: By similarity xref: UniProtKB:O95477 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034197 ! ABCA1_HUMAN [Term] id: CCO:B0034499 name: ABCA1_HUMAN-Phosphoserine2054 def: "Protein ABCA1_HUMAN with the residue 2054 substituted with Phosphoserine" [UniProtKB:O95477] comment: by PKA; xref: UniProtKB:O95477 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034197 ! ABCA1_HUMAN [Term] id: CCO:B0034500 name: ACTC_HUMAN-N-acetylaspartate3 def: "Protein ACTC_HUMAN with the residue 3 substituted with N-acetylaspartate" [UniProtKB:P68032] comment: By similarity xref: UniProtKB:P68032 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015638 ! ACTC_HUMAN [Term] id: CCO:B0034501 name: ACTC_HUMAN-Tele-methylhistidine75 def: "Protein ACTC_HUMAN with the residue 75 substituted with Tele-methylhistidine" [UniProtKB:P68032] comment: By similarity xref: UniProtKB:P68032 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015638 ! ACTC_HUMAN [Term] id: CCO:B0034502 name: ACTG_HUMAN-N-acetylmethionine1 def: "Protein ACTG_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P63261] comment: By similarity xref: UniProtKB:P63261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:B0034503 name: ACTG_HUMAN-N-acetylglutamate2 def: "Protein ACTG_HUMAN with the residue 2 substituted with N-acetylglutamate" [UniProtKB:P63261] xref: UniProtKB:P63261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:B0034504 name: ACTG_HUMAN-Tele-methylhistidine73 def: "Protein ACTG_HUMAN with the residue 73 substituted with Tele-methylhistidine" [UniProtKB:P63261] comment: By similarity xref: UniProtKB:P63261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:B0034505 name: ACTG_HUMAN-Phosphotyrosine169 def: "Protein ACTG_HUMAN with the residue 169 substituted with Phosphotyrosine" [UniProtKB:P63261] comment: By similarity xref: UniProtKB:P63261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:B0034506 name: ACTH_HUMAN-N-acetylglutamate3 def: "Protein ACTH_HUMAN with the residue 3 substituted with N-acetylglutamate" [UniProtKB:P63267] comment: By similarity xref: UniProtKB:P63267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015644 ! ACTH_HUMAN [Term] id: CCO:B0034526 name: AFG32_HUMAN-N6-acetyllysine308 def: "Protein AFG32_HUMAN with the residue 308 substituted with N6-acetyllysine" [UniProtKB:Q9Y4W6] comment: By similarity xref: UniProtKB:Q9Y4W6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: transformation_of CCO:B0025289 ! AFG32_HUMAN [Term] id: CCO:B0034527 name: AFG32_HUMAN-N6-acetyllysine543 def: "Protein AFG32_HUMAN with the residue 543 substituted with N6-acetyllysine" [UniProtKB:Q9Y4W6] comment: By similarity xref: UniProtKB:Q9Y4W6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025289 ! AFG32_HUMAN [Term] id: CCO:B0034528 name: AIFM1_HUMAN-N6-acetyllysine593 def: "Protein AIFM1_HUMAN with the residue 593 substituted with N6-acetyllysine" [UniProtKB:O95831] comment: By similarity xref: UniProtKB:O95831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:B0034529 name: AKP8L_HUMAN-Phosphoserine283 def: "Protein AKP8L_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q9ULX6] xref: UniProtKB:Q9ULX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:B0034531 name: AMD_HUMAN-Phosphoserine918 def: "Protein AMD_HUMAN with the residue 918 substituted with Phosphoserine" [UniProtKB:P19021] comment: By similarity xref: UniProtKB:P19021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023175 ! AMD_HUMAN [Term] id: CCO:B0034532 name: AMD_HUMAN-Phosphoserine955 def: "Protein AMD_HUMAN with the residue 955 substituted with Phosphoserine" [UniProtKB:P19021] xref: UniProtKB:P19021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0000901 ! peptidylglycine monooxygenase activity relationship: has_function CCO:F0000980 ! peptidylamidoglycolate lyase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000985 ! secretory granule relationship: transformation_of CCO:B0023175 ! AMD_HUMAN [Term] id: CCO:B0034533 name: AMD_HUMAN-Phosphoserine957 def: "Protein AMD_HUMAN with the residue 957 substituted with Phosphoserine" [UniProtKB:P19021] xref: UniProtKB:P19021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023175 ! AMD_HUMAN [Term] id: CCO:B0034534 name: AMD_HUMAN-Sulfotyrosine961 def: "Protein AMD_HUMAN with the residue 961 substituted with Sulfotyrosine" [UniProtKB:P19021] xref: UniProtKB:P19021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023175 ! AMD_HUMAN [Term] id: CCO:B0034535 name: AMPM1_HUMAN-Phosphotyrosine253 def: "Protein AMPM1_HUMAN with the residue 253 substituted with Phosphotyrosine" [UniProtKB:P53582] xref: UniProtKB:P53582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029151 ! AMPM1_HUMAN [Term] id: CCO:B0034544 name: ANPRA_HUMAN-Phosphoserine529 def: "Protein ANPRA_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:P16066] comment: By similarity xref: UniProtKB:P16066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016680 ! ANPRA_HUMAN [Term] id: CCO:B0034545 name: ANPRA_HUMAN-Phosphothreonine532 def: "Protein ANPRA_HUMAN with the residue 532 substituted with Phosphothreonine" [UniProtKB:P16066] comment: By similarity xref: UniProtKB:P16066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016680 ! ANPRA_HUMAN [Term] id: CCO:B0034546 name: ANPRA_HUMAN-Phosphoserine534 def: "Protein ANPRA_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:P16066] comment: By similarity xref: UniProtKB:P16066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001980 ! peptide receptor activity, G-protein coupled relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_function CCO:F0005682 ! hormone binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0016680 ! ANPRA_HUMAN [Term] id: CCO:B0034547 name: ANPRA_HUMAN-Phosphoserine538 def: "Protein ANPRA_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:P16066] comment: By similarity xref: UniProtKB:P16066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016680 ! ANPRA_HUMAN [Term] id: CCO:B0034548 name: ANPRA_HUMAN-Phosphoserine542 def: "Protein ANPRA_HUMAN with the residue 542 substituted with Phosphoserine" [UniProtKB:P16066] comment: By similarity xref: UniProtKB:P16066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016680 ! ANPRA_HUMAN [Term] id: CCO:B0034549 name: ANPRA_HUMAN-Phosphothreonine545 def: "Protein ANPRA_HUMAN with the residue 545 substituted with Phosphothreonine" [UniProtKB:P16066] comment: By similarity xref: UniProtKB:P16066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016680 ! ANPRA_HUMAN [Term] id: CCO:B0034550 name: ANPRB_HUMAN-Phosphoserine513 def: "Protein ANPRB_HUMAN with the residue 513 substituted with Phosphoserine" [UniProtKB:P20594] comment: By similarity xref: UniProtKB:P20594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016681 ! ANPRB_HUMAN [Term] id: CCO:B0034551 name: ANPRB_HUMAN-Phosphothreonine516 def: "Protein ANPRB_HUMAN with the residue 516 substituted with Phosphothreonine" [UniProtKB:P20594] comment: By similarity xref: UniProtKB:P20594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016681 ! ANPRB_HUMAN [Term] id: CCO:B0034552 name: ANPRB_HUMAN-Phosphoserine518 def: "Protein ANPRB_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:P20594] comment: By similarity xref: UniProtKB:P20594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001980 ! peptide receptor activity, G-protein coupled relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0016681 ! ANPRB_HUMAN [Term] id: CCO:B0034553 name: ANPRB_HUMAN-Phosphoserine523 def: "Protein ANPRB_HUMAN with the residue 523 substituted with Phosphoserine" [UniProtKB:P20594] comment: By similarity xref: UniProtKB:P20594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016681 ! ANPRB_HUMAN [Term] id: CCO:B0034554 name: ANPRB_HUMAN-Phosphoserine526 def: "Protein ANPRB_HUMAN with the residue 526 substituted with Phosphoserine" [UniProtKB:P20594] comment: By similarity xref: UniProtKB:P20594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016681 ! ANPRB_HUMAN [Term] id: CCO:B0034555 name: ANXA5_HUMAN-N-acetylalanine2 def: "Protein ANXA5_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P08758] xref: UniProtKB:P08758 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015822 ! ANXA5_HUMAN [Term] id: CCO:B0034556 name: ANXA5_HUMAN-N6-acetyllysine101 def: "Protein ANXA5_HUMAN with the residue 101 substituted with N6-acetyllysine" [UniProtKB:P08758] xref: UniProtKB:P08758 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015822 ! ANXA5_HUMAN [Term] id: CCO:B0034557 name: ANXA9_HUMAN-Phosphoserine2 def: "Protein ANXA9_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:O76027] xref: UniProtKB:O76027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000215 ! phosphatidylserine binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000709 ! cell surface relationship: transformation_of CCO:B0015830 ! ANXA9_HUMAN [Term] id: CCO:B0034558 name: AQP1_HUMAN-Phosphothreonine246 def: "Protein AQP1_HUMAN with the residue 246 substituted with Phosphothreonine" [UniProtKB:P29972] comment: By similarity xref: UniProtKB:P29972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034159 ! AQP1_HUMAN [Term] id: CCO:B0034559 name: AQP1_HUMAN-Phosphoserine247 def: "Protein AQP1_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:P29972] comment: By similarity xref: UniProtKB:P29972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034159 ! AQP1_HUMAN [Term] id: CCO:B0034560 name: AQP1_HUMAN-Phosphoserine262 def: "Protein AQP1_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:P29972] comment: By similarity xref: UniProtKB:P29972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034159 ! AQP1_HUMAN [Term] id: CCO:B0034561 name: ARI4B_HUMAN-Phosphoserine710 def: "Protein ARI4B_HUMAN with the residue 710 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0034562 name: ARI4B_HUMAN-Phosphoserine712 def: "Protein ARI4B_HUMAN with the residue 712 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0034563 name: ARI4B_HUMAN-Phosphoserine713 def: "Protein ARI4B_HUMAN with the residue 713 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0034564 name: ARI4B_HUMAN-Phosphoserine717 def: "Protein ARI4B_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0034565 name: ARI4B_HUMAN-Phosphothreonine1022 def: "Protein ARI4B_HUMAN with the residue 1022 substituted with Phosphothreonine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0034566 name: ARI4B_HUMAN-Phosphoserine1029 def: "Protein ARI4B_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0034567 name: ARP3_HUMAN-N-acetylalanine2 def: "Protein ARP3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P61158] xref: UniProtKB:P61158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000443 ! Arp2/3 protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0021502 ! ARP3_HUMAN [Term] id: CCO:B0034568 name: ARP3_HUMAN-Phosphotyrosine231 def: "Protein ARP3_HUMAN with the residue 231 substituted with Phosphotyrosine" [UniProtKB:P61158] xref: UniProtKB:P61158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021502 ! ARP3_HUMAN [Term] id: CCO:B0034569 name: ARP3_HUMAN-Phosphoserine418 def: "Protein ARP3_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:P61158] comment: By similarity xref: UniProtKB:P61158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021502 ! ARP3_HUMAN [Term] id: CCO:B0034581 name: ATS8_HUMAN-Phosphotyrosine255 def: "Protein ATS8_HUMAN with the residue 255 substituted with Phosphotyrosine" [UniProtKB:Q9UP79] xref: UniProtKB:Q9UP79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002399 ! low affinity phosphate transmembrane transporter activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0001109 ! extracellular matrix relationship: transformation_of CCO:B0019651 ! ATS8_HUMAN [Term] id: CCO:B0034582 name: ATS8_HUMAN-Phosphoserine259 def: "Protein ATS8_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:Q9UP79] xref: UniProtKB:Q9UP79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019651 ! ATS8_HUMAN [Term] id: CCO:B0034583 name: B2L13_HUMAN-Phosphoserine420 def: "Protein B2L13_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:Q9BXK5] xref: UniProtKB:Q9BXK5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: transformation_of CCO:B0026744 ! B2L13_HUMAN [Term] id: CCO:B0034584 name: B2L13_HUMAN-Phosphoserine426 def: "Protein B2L13_HUMAN with the residue 426 substituted with Phosphoserine" [UniProtKB:Q9BXK5] xref: UniProtKB:Q9BXK5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026744 ! B2L13_HUMAN [Term] id: CCO:B0034589 name: BPA1_HUMAN-Phosphoserine172 def: "Protein BPA1_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q03001] xref: UniProtKB:Q03001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017433 ! BPA1_HUMAN [Term] id: CCO:B0034590 name: BPA1_HUMAN-Phosphoserine174 def: "Protein BPA1_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:Q03001] xref: UniProtKB:Q03001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017433 ! BPA1_HUMAN [Term] id: CCO:B0034591 name: BPA1_HUMAN-Phosphoserine176 def: "Protein BPA1_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q03001] xref: UniProtKB:Q03001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017433 ! BPA1_HUMAN [Term] id: CCO:B0034592 name: BPA1_HUMAN-Phosphothreonine224 def: "Protein BPA1_HUMAN with the residue 224 substituted with Phosphothreonine" [UniProtKB:Q03001] xref: UniProtKB:Q03001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000938 ! hemidesmosome relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: transformation_of CCO:B0017433 ! BPA1_HUMAN [Term] id: CCO:B0034593 name: BPA1_HUMAN-Phosphothreonine226 def: "Protein BPA1_HUMAN with the residue 226 substituted with Phosphothreonine" [UniProtKB:Q03001] xref: UniProtKB:Q03001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017433 ! BPA1_HUMAN [Term] id: CCO:B0034607 name: BTAF1_HUMAN-Phosphoserine237 def: "Protein BTAF1_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:O14981] xref: UniProtKB:O14981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0016937 ! BTAF1_HUMAN [Term] id: CCO:B0034613 name: CCNL2_HUMAN-Phosphoserine345 def: "Protein CCNL2_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q96S94] xref: UniProtKB:Q96S94 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023940 ! CCNL2_HUMAN [Term] id: CCO:B0034614 name: CCNL2_HUMAN-Phosphoserine351 def: "Protein CCNL2_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q96S94] xref: UniProtKB:Q96S94 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0023940 ! CCNL2_HUMAN [Term] id: CCO:B0034615 name: CCNL2_HUMAN-Phosphoserine369 def: "Protein CCNL2_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:Q96S94] xref: UniProtKB:Q96S94 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023940 ! CCNL2_HUMAN [Term] id: CCO:B0034639 name: CDYL1_HUMAN-Phosphoserine88 def: "Protein CDYL1_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q9Y232] xref: UniProtKB:Q9Y232 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028736 ! CDYL1_HUMAN [Term] id: CCO:B0034640 name: CDYL1_HUMAN-Phosphoserine201 def: "Protein CDYL1_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:Q9Y232] xref: UniProtKB:Q9Y232 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0028736 ! CDYL1_HUMAN [Term] id: CCO:B0034641 name: CEAM1_HUMAN-Pyrrolidone carboxylic acid35 def: "Protein CEAM1_HUMAN with the residue 35 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P13688] xref: UniProtKB:P13688 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029727 ! CEAM1_HUMAN [Term] id: CCO:B0034642 name: CELR2_HUMAN-3-hydroxyasparagine1591 def: "Protein CELR2_HUMAN with the residue 1591 substituted with 3-hydroxyasparagine" [UniProtKB:Q9HCU4] comment: Potential xref: UniProtKB:Q9HCU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032349 ! CELR2_HUMAN [Term] id: CCO:B0034643 name: CELR2_HUMAN-3-hydroxyasparagine1810 def: "Protein CELR2_HUMAN with the residue 1810 substituted with 3-hydroxyasparagine" [UniProtKB:Q9HCU4] comment: Potential xref: UniProtKB:Q9HCU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032349 ! CELR2_HUMAN [Term] id: CCO:B0034644 name: CENB1_HUMAN-Nitrated tyrosine485 def: "Protein CENB1_HUMAN with the residue 485 substituted with Nitrated tyrosine" [UniProtKB:Q15027] xref: UniProtKB:Q15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033903 ! CENB1_HUMAN [Term] id: CCO:B0034645 name: CENB1_HUMAN-Phosphoserine554 def: "Protein CENB1_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:Q15027] comment: by PKB; xref: UniProtKB:Q15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033903 ! CENB1_HUMAN [Term] id: CCO:B0034646 name: CENB2_HUMAN-Phosphoserine521 def: "Protein CENB2_HUMAN with the residue 521 substituted with Phosphoserine" [UniProtKB:Q15057] xref: UniProtKB:Q15057 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033904 ! CENB2_HUMAN [Term] id: CCO:B0034647 name: CENB2_HUMAN-Phosphotyrosine742 def: "Protein CENB2_HUMAN with the residue 742 substituted with Phosphotyrosine" [UniProtKB:Q15057] xref: UniProtKB:Q15057 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033904 ! CENB2_HUMAN [Term] id: CCO:B0034648 name: CENB2_HUMAN-Phosphotyrosine750 def: "Protein CENB2_HUMAN with the residue 750 substituted with Phosphotyrosine" [UniProtKB:Q15057] xref: UniProtKB:Q15057 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033904 ! CENB2_HUMAN [Term] id: CCO:B0034649 name: CENB2_HUMAN-Phosphoserine775 def: "Protein CENB2_HUMAN with the residue 775 substituted with Phosphoserine" [UniProtKB:Q15057] xref: UniProtKB:Q15057 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033904 ! CENB2_HUMAN [Term] id: CCO:B0034650 name: CEND1_HUMAN-Phosphotyrosine77 def: "Protein CEND1_HUMAN with the residue 77 substituted with Phosphotyrosine" [UniProtKB:Q8WZ64] comment: By similarity xref: UniProtKB:Q8WZ64 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024600 ! CEND1_HUMAN [Term] id: CCO:B0034651 name: CEND1_HUMAN-Phosphotyrosine473 def: "Protein CEND1_HUMAN with the residue 473 substituted with Phosphotyrosine" [UniProtKB:Q8WZ64] comment: By similarity xref: UniProtKB:Q8WZ64 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024600 ! CEND1_HUMAN [Term] id: CCO:B0034652 name: CEND1_HUMAN-Phosphoserine1600 def: "Protein CEND1_HUMAN with the residue 1600 substituted with Phosphoserine" [UniProtKB:Q8WZ64] xref: UniProtKB:Q8WZ64 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024600 ! CEND1_HUMAN [Term] id: CCO:B0034654 name: CHD1_HUMAN-Phosphoserine5 def: "Protein CHD1_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:O14646] comment: By similarity xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034655 name: CHD1_HUMAN-Phosphoserine89 def: "Protein CHD1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034656 name: CHD1_HUMAN-Phosphoserine215 def: "Protein CHD1_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034657 name: CHD1_HUMAN-Phosphoserine216 def: "Protein CHD1_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034658 name: CHD1_HUMAN-Phosphotyrosine1068 def: "Protein CHD1_HUMAN with the residue 1068 substituted with Phosphotyrosine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034659 name: CHD1_HUMAN-Phosphoserine1353 def: "Protein CHD1_HUMAN with the residue 1353 substituted with Phosphoserine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034660 name: CHD1_HUMAN-Phosphoserine1355 def: "Protein CHD1_HUMAN with the residue 1355 substituted with Phosphoserine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034661 name: CHD1_HUMAN-Phosphoserine1356 def: "Protein CHD1_HUMAN with the residue 1356 substituted with Phosphoserine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034662 name: CHD1_HUMAN-Phosphoserine1360 def: "Protein CHD1_HUMAN with the residue 1360 substituted with Phosphoserine" [UniProtKB:O14646] xref: UniProtKB:O14646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021030 ! CHD1_HUMAN [Term] id: CCO:B0034669 name: CLOCK_HUMAN-Phosphoserine408 def: "Protein CLOCK_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:O15516] comment: By similarity xref: UniProtKB:O15516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026531 ! CLOCK_HUMAN [Term] id: CCO:B0034671 name: COF1_HUMAN-N-acetylalanine2 def: "Protein COF1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P23528] xref: UniProtKB:P23528 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:B0034672 name: COF1_HUMAN-Phosphoserine3 def: "Protein COF1_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:P23528] comment: by NRK; xref: UniProtKB:P23528 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:B0034673 name: COF1_HUMAN-Phosphothreonine25 def: "Protein COF1_HUMAN with the residue 25 substituted with Phosphothreonine" [UniProtKB:P23528] xref: UniProtKB:P23528 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:B0034674 name: COF1_HUMAN-Phosphotyrosine68 def: "Protein COF1_HUMAN with the residue 68 substituted with Phosphotyrosine" [UniProtKB:P23528] comment: By similarity xref: UniProtKB:P23528 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:B0034675 name: COF1_HUMAN-N6-acetyllysine132 def: "Protein COF1_HUMAN with the residue 132 substituted with N6-acetyllysine" [UniProtKB:P23528] xref: UniProtKB:P23528 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:B0034676 name: COF1_HUMAN-Phosphotyrosine140 def: "Protein COF1_HUMAN with the residue 140 substituted with Phosphotyrosine" [UniProtKB:P23528] xref: UniProtKB:P23528 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:B0034677 name: COF1_HUMAN-Phosphoserine156 def: "Protein COF1_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:P23528] xref: UniProtKB:P23528 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:B0034678 name: COF2_HUMAN-Phosphoserine3 def: "Protein COF2_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:Q9Y281] xref: UniProtKB:Q9Y281 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0033309 ! COF2_HUMAN [Term] id: CCO:B0034679 name: COF2_HUMAN-Phosphoserine24 def: "Protein COF2_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q9Y281] comment: By similarity xref: UniProtKB:Q9Y281 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033309 ! COF2_HUMAN [Term] id: CCO:B0034680 name: COF2_HUMAN-Phosphotyrosine89 def: "Protein COF2_HUMAN with the residue 89 substituted with Phosphotyrosine" [UniProtKB:Q9Y281] xref: UniProtKB:Q9Y281 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033309 ! COF2_HUMAN [Term] id: CCO:B0034681 name: COR1B_HUMAN-Phosphoserine2 def: "Protein COR1B_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q9BR76] comment: by PKC; xref: UniProtKB:Q9BR76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0025107 ! COR1B_HUMAN [Term] id: CCO:B0034682 name: COR1C_HUMAN-Phosphotyrosine301 def: "Protein COR1C_HUMAN with the residue 301 substituted with Phosphotyrosine" [UniProtKB:Q9ULV4] xref: UniProtKB:Q9ULV4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025115 ! COR1C_HUMAN [Term] id: CCO:B0034696 name: DDX56_HUMAN-Phosphoserine126 def: "Protein DDX56_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q9NY93] xref: UniProtKB:Q9NY93 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0030377 ! DDX56_HUMAN [Term] id: CCO:B0034697 name: DEST_HUMAN-N-acetylalanine2 def: "Protein DEST_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P60981] xref: UniProtKB:P60981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033316 ! DEST_HUMAN [Term] id: CCO:B0034698 name: DEST_HUMAN-Phosphoserine3 def: "Protein DEST_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:P60981] xref: UniProtKB:P60981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033316 ! DEST_HUMAN [Term] id: CCO:B0034699 name: DLG3_HUMAN-Phosphotyrosine673 def: "Protein DLG3_HUMAN with the residue 673 substituted with Phosphotyrosine" [UniProtKB:Q92796] xref: UniProtKB:Q92796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023306 ! DLG3_HUMAN [Term] id: CCO:B0034700 name: DLG4_HUMAN-Phosphoserine142 def: "Protein DLG4_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034701 name: DLG4_HUMAN-Phosphotyrosine240 def: "Protein DLG4_HUMAN with the residue 240 substituted with Phosphotyrosine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034702 name: DLG4_HUMAN-Phosphoserine295 def: "Protein DLG4_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034703 name: DLG4_HUMAN-Phosphotyrosine397 def: "Protein DLG4_HUMAN with the residue 397 substituted with Phosphotyrosine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034704 name: DLG4_HUMAN-Phosphoserine415 def: "Protein DLG4_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034705 name: DLG4_HUMAN-Phosphoserine418 def: "Protein DLG4_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034706 name: DLG4_HUMAN-Phosphotyrosine432 def: "Protein DLG4_HUMAN with the residue 432 substituted with Phosphotyrosine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001055 ! cortical cytoskeleton relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034707 name: DLG4_HUMAN-Phosphotyrosine580 def: "Protein DLG4_HUMAN with the residue 580 substituted with Phosphotyrosine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034708 name: DLG4_HUMAN-Phosphotyrosine604 def: "Protein DLG4_HUMAN with the residue 604 substituted with Phosphotyrosine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034709 name: DLG4_HUMAN-Phosphotyrosine715 def: "Protein DLG4_HUMAN with the residue 715 substituted with Phosphotyrosine" [UniProtKB:P78352] comment: By similarity xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0034710 name: DNJB4_HUMAN-Phosphotyrosine172 def: "Protein DNJB4_HUMAN with the residue 172 substituted with Phosphotyrosine" [UniProtKB:Q9UDY4] xref: UniProtKB:Q9UDY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016224 ! DNJB4_HUMAN [Term] id: CCO:B0034711 name: DNMT1_HUMAN-Phosphoserine127 def: "Protein DNMT1_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000405 ! DNA (cytosine-5-)-methyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000119 ! heterochromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000265 ! replication fork relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034712 name: DNMT1_HUMAN-Phosphoserine154 def: "Protein DNMT1_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034713 name: DNMT1_HUMAN-Phosphoserine509 def: "Protein DNMT1_HUMAN with the residue 509 substituted with Phosphoserine" [UniProtKB:P26358] comment: By similarity xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034714 name: DNMT1_HUMAN-Phosphoserine714 def: "Protein DNMT1_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034715 name: DNMT1_HUMAN-Phosphoserine954 def: "Protein DNMT1_HUMAN with the residue 954 substituted with Phosphoserine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034716 name: DNMT1_HUMAN-Phosphoserine1105 def: "Protein DNMT1_HUMAN with the residue 1105 substituted with Phosphoserine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034717 name: DNMT1_HUMAN-N6-acetyllysine1113 def: "Protein DNMT1_HUMAN with the residue 1113 substituted with N6-acetyllysine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034718 name: DNMT1_HUMAN-N6-acetyllysine1115 def: "Protein DNMT1_HUMAN with the residue 1115 substituted with N6-acetyllysine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034719 name: DNMT1_HUMAN-N6-acetyllysine1117 def: "Protein DNMT1_HUMAN with the residue 1117 substituted with N6-acetyllysine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0034720 name: DYN1_HUMAN-Phosphotyrosine80 def: "Protein DYN1_HUMAN with the residue 80 substituted with Phosphotyrosine" [UniProtKB:Q05193] comment: By similarity xref: UniProtKB:Q05193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:B0034721 name: DYN1_HUMAN-Phosphotyrosine125 def: "Protein DYN1_HUMAN with the residue 125 substituted with Phosphotyrosine" [UniProtKB:Q05193] comment: By similarity xref: UniProtKB:Q05193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:B0034722 name: DYN1_HUMAN-Phosphotyrosine354 def: "Protein DYN1_HUMAN with the residue 354 substituted with Phosphotyrosine" [UniProtKB:Q05193] xref: UniProtKB:Q05193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:B0034724 name: EFS_HUMAN-Phosphotyrosine253 def: "Protein EFS_HUMAN with the residue 253 substituted with Phosphotyrosine" [UniProtKB:O43281] comment: by SRC; By similarity xref: UniProtKB:O43281 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0028938 ! EFS_HUMAN [Term] id: CCO:B0034727 name: EPHA1_HUMAN-Phosphothreonine33 def: "Protein EPHA1_HUMAN with the residue 33 substituted with Phosphothreonine" [UniProtKB:P21709] xref: UniProtKB:P21709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:B0034728 name: EPHA1_HUMAN-Phosphoserine34 def: "Protein EPHA1_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P21709] xref: UniProtKB:P21709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:B0034729 name: EPHA1_HUMAN-Phosphotyrosine599 def: "Protein EPHA1_HUMAN with the residue 599 substituted with Phosphotyrosine" [UniProtKB:P21709] comment: by autocatalysis; Potential xref: UniProtKB:P21709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:B0034730 name: EPHA1_HUMAN-Phosphotyrosine605 def: "Protein EPHA1_HUMAN with the residue 605 substituted with Phosphotyrosine" [UniProtKB:P21709] comment: by autocatalysis; Potential xref: UniProtKB:P21709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:B0034731 name: EPHA1_HUMAN-Phosphotyrosine781 def: "Protein EPHA1_HUMAN with the residue 781 substituted with Phosphotyrosine" [UniProtKB:P21709] comment: by autocatalysis; Potential xref: UniProtKB:P21709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:B0034732 name: EPHA1_HUMAN-Phosphoserine910 def: "Protein EPHA1_HUMAN with the residue 910 substituted with Phosphoserine" [UniProtKB:P21709] comment: By similarity xref: UniProtKB:P21709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:B0034733 name: EPHA1_HUMAN-Phosphotyrosine930 def: "Protein EPHA1_HUMAN with the residue 930 substituted with Phosphotyrosine" [UniProtKB:P21709] comment: by autocatalysis; Potential xref: UniProtKB:P21709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:B0034734 name: EPHA3_HUMAN-Phosphotyrosine596 def: "Protein EPHA3_HUMAN with the residue 596 substituted with Phosphotyrosine" [UniProtKB:P29320] comment: by autocatalysis; Potential xref: UniProtKB:P29320 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014967 ! EPHA3_HUMAN [Term] id: CCO:B0034735 name: EPHA3_HUMAN-Phosphotyrosine602 def: "Protein EPHA3_HUMAN with the residue 602 substituted with Phosphotyrosine" [UniProtKB:P29320] comment: by autocatalysis; Potential xref: UniProtKB:P29320 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014967 ! EPHA3_HUMAN [Term] id: CCO:B0034736 name: EPHA3_HUMAN-Phosphotyrosine779 def: "Protein EPHA3_HUMAN with the residue 779 substituted with Phosphotyrosine" [UniProtKB:P29320] comment: by autocatalysis; xref: UniProtKB:P29320 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014967 ! EPHA3_HUMAN [Term] id: CCO:B0034737 name: EPHA3_HUMAN-Phosphotyrosine937 def: "Protein EPHA3_HUMAN with the residue 937 substituted with Phosphotyrosine" [UniProtKB:P29320] comment: By similarity xref: UniProtKB:P29320 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014967 ! EPHA3_HUMAN [Term] id: CCO:B0034738 name: EPHA4_HUMAN-Phosphotyrosine596 def: "Protein EPHA4_HUMAN with the residue 596 substituted with Phosphotyrosine" [UniProtKB:P54764] comment: by autocatalysis; By similarity xref: UniProtKB:P54764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014942 ! EPHA4_HUMAN [Term] id: CCO:B0034739 name: EPHA4_HUMAN-Phosphotyrosine602 def: "Protein EPHA4_HUMAN with the residue 602 substituted with Phosphotyrosine" [UniProtKB:P54764] comment: by autocatalysis; By similarity xref: UniProtKB:P54764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014942 ! EPHA4_HUMAN [Term] id: CCO:B0034740 name: EPHA4_HUMAN-Phosphotyrosine779 def: "Protein EPHA4_HUMAN with the residue 779 substituted with Phosphotyrosine" [UniProtKB:P54764] comment: by autocatalysis; Potential xref: UniProtKB:P54764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014942 ! EPHA4_HUMAN [Term] id: CCO:B0034741 name: EPHA4_HUMAN-Phosphotyrosine928 def: "Protein EPHA4_HUMAN with the residue 928 substituted with Phosphotyrosine" [UniProtKB:P54764] comment: by autocatalysis; Potential xref: UniProtKB:P54764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014942 ! EPHA4_HUMAN [Term] id: CCO:B0034742 name: EPHA5_HUMAN-Phosphotyrosine650 def: "Protein EPHA5_HUMAN with the residue 650 substituted with Phosphotyrosine" [UniProtKB:P54756] comment: by autocatalysis; By similarity xref: UniProtKB:P54756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001342 ! transmembrane-ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014944 ! EPHA5_HUMAN [Term] id: CCO:B0034743 name: EPHA5_HUMAN-Phosphotyrosine656 def: "Protein EPHA5_HUMAN with the residue 656 substituted with Phosphotyrosine" [UniProtKB:P54756] comment: by autocatalysis; By similarity xref: UniProtKB:P54756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014944 ! EPHA5_HUMAN [Term] id: CCO:B0034744 name: EPHA5_HUMAN-Phosphotyrosine833 def: "Protein EPHA5_HUMAN with the residue 833 substituted with Phosphotyrosine" [UniProtKB:P54756] comment: by autocatalysis; Potential xref: UniProtKB:P54756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014944 ! EPHA5_HUMAN [Term] id: CCO:B0034745 name: EPHA5_HUMAN-Phosphotyrosine982 def: "Protein EPHA5_HUMAN with the residue 982 substituted with Phosphotyrosine" [UniProtKB:P54756] comment: by autocatalysis; By similarity xref: UniProtKB:P54756 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014944 ! EPHA5_HUMAN [Term] id: CCO:B0034746 name: EPHA6_HUMAN-Phosphotyrosine605 def: "Protein EPHA6_HUMAN with the residue 605 substituted with Phosphotyrosine" [UniProtKB:Q9UF33] comment: by autocatalysis; Potential xref: UniProtKB:Q9UF33 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014941 ! EPHA6_HUMAN [Term] id: CCO:B0034747 name: EPHA6_HUMAN-Phosphotyrosine611 def: "Protein EPHA6_HUMAN with the residue 611 substituted with Phosphotyrosine" [UniProtKB:Q9UF33] comment: by autocatalysis; Potential xref: UniProtKB:Q9UF33 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014941 ! EPHA6_HUMAN [Term] id: CCO:B0034748 name: EPHA6_HUMAN-Phosphotyrosine830 def: "Protein EPHA6_HUMAN with the residue 830 substituted with Phosphotyrosine" [UniProtKB:Q9UF33] comment: by autocatalysis; Potential xref: UniProtKB:Q9UF33 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014941 ! EPHA6_HUMAN [Term] id: CCO:B0034749 name: EPHA6_HUMAN-Phosphotyrosine977 def: "Protein EPHA6_HUMAN with the residue 977 substituted with Phosphotyrosine" [UniProtKB:Q9UF33] comment: by autocatalysis; Potential xref: UniProtKB:Q9UF33 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014941 ! EPHA6_HUMAN [Term] id: CCO:B0034750 name: EPHA7_HUMAN-Phosphotyrosine608 def: "Protein EPHA7_HUMAN with the residue 608 substituted with Phosphotyrosine" [UniProtKB:Q15375] comment: by autocatalysis; Potential xref: UniProtKB:Q15375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014961 ! EPHA7_HUMAN [Term] id: CCO:B0034751 name: EPHA7_HUMAN-Phosphotyrosine614 def: "Protein EPHA7_HUMAN with the residue 614 substituted with Phosphotyrosine" [UniProtKB:Q15375] comment: by autocatalysis; Potential xref: UniProtKB:Q15375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014961 ! EPHA7_HUMAN [Term] id: CCO:B0034752 name: EPHA7_HUMAN-Phosphotyrosine791 def: "Protein EPHA7_HUMAN with the residue 791 substituted with Phosphotyrosine" [UniProtKB:Q15375] comment: by autocatalysis; Potential xref: UniProtKB:Q15375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014961 ! EPHA7_HUMAN [Term] id: CCO:B0034753 name: EPHA7_HUMAN-Phosphotyrosine940 def: "Protein EPHA7_HUMAN with the residue 940 substituted with Phosphotyrosine" [UniProtKB:Q15375] comment: by autocatalysis; Potential xref: UniProtKB:Q15375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014961 ! EPHA7_HUMAN [Term] id: CCO:B0034754 name: EPHA8_HUMAN-Phosphotyrosine616 def: "Protein EPHA8_HUMAN with the residue 616 substituted with Phosphotyrosine" [UniProtKB:P29322] comment: by autocatalysis; By similarity xref: UniProtKB:P29322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014957 ! EPHA8_HUMAN [Term] id: CCO:B0034755 name: EPHA8_HUMAN-Phosphotyrosine839 def: "Protein EPHA8_HUMAN with the residue 839 substituted with Phosphotyrosine" [UniProtKB:P29322] comment: by autocatalysis; By similarity xref: UniProtKB:P29322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014957 ! EPHA8_HUMAN [Term] id: CCO:B0034756 name: EPHB1_HUMAN-Phosphotyrosine594 def: "Protein EPHB1_HUMAN with the residue 594 substituted with Phosphotyrosine" [UniProtKB:P54762] comment: by autocatalysis; xref: UniProtKB:P54762 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014969 ! EPHB1_HUMAN [Term] id: CCO:B0034757 name: EPHB1_HUMAN-Phosphotyrosine600 def: "Protein EPHB1_HUMAN with the residue 600 substituted with Phosphotyrosine" [UniProtKB:P54762] comment: by autocatalysis; Potential xref: UniProtKB:P54762 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014969 ! EPHB1_HUMAN [Term] id: CCO:B0034758 name: EPHB1_HUMAN-Phosphotyrosine778 def: "Protein EPHB1_HUMAN with the residue 778 substituted with Phosphotyrosine" [UniProtKB:P54762] comment: by autocatalysis; Potential xref: UniProtKB:P54762 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014969 ! EPHB1_HUMAN [Term] id: CCO:B0034759 name: EPHB1_HUMAN-Phosphotyrosine928 def: "Protein EPHB1_HUMAN with the residue 928 substituted with Phosphotyrosine" [UniProtKB:P54762] comment: by autocatalysis; xref: UniProtKB:P54762 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014969 ! EPHB1_HUMAN [Term] id: CCO:B0034760 name: EPHB3_HUMAN-Phosphotyrosine608 def: "Protein EPHB3_HUMAN with the residue 608 substituted with Phosphotyrosine" [UniProtKB:P54753] comment: by autocatalysis; By similarity xref: UniProtKB:P54753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014968 ! EPHB3_HUMAN [Term] id: CCO:B0034761 name: EPHB3_HUMAN-Phosphotyrosine614 def: "Protein EPHB3_HUMAN with the residue 614 substituted with Phosphotyrosine" [UniProtKB:P54753] comment: by autocatalysis; By similarity xref: UniProtKB:P54753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014968 ! EPHB3_HUMAN [Term] id: CCO:B0034762 name: EPHB3_HUMAN-Phosphotyrosine792 def: "Protein EPHB3_HUMAN with the residue 792 substituted with Phosphotyrosine" [UniProtKB:P54753] comment: by autocatalysis; Potential xref: UniProtKB:P54753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014968 ! EPHB3_HUMAN [Term] id: CCO:B0034763 name: EPHB3_HUMAN-Phosphotyrosine942 def: "Protein EPHB3_HUMAN with the residue 942 substituted with Phosphotyrosine" [UniProtKB:P54753] comment: by autocatalysis; By similarity xref: UniProtKB:P54753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014968 ! EPHB3_HUMAN [Term] id: CCO:B0034768 name: ETV6_HUMAN-Phosphoserine22 def: "Protein ETV6_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:P41212] xref: UniProtKB:P41212 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028354 ! ETV6_HUMAN [Term] id: CCO:B0034769 name: ETV6_HUMAN-Phosphoserine257 def: "Protein ETV6_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:P41212] comment: by MAPK14; xref: UniProtKB:P41212 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0028354 ! ETV6_HUMAN [Term] id: CCO:B0034770 name: EZRI_HUMAN-Phosphotyrosine146 def: "Protein EZRI_HUMAN with the residue 146 substituted with Phosphotyrosine" [UniProtKB:P15311] comment: by PDGFR; xref: UniProtKB:P15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018212 ! EZRI_HUMAN [Term] id: CCO:B0034771 name: EZRI_HUMAN-Phosphotyrosine354 def: "Protein EZRI_HUMAN with the residue 354 substituted with Phosphotyrosine" [UniProtKB:P15311] comment: by PDGFR; xref: UniProtKB:P15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0005879 ! protein self-association relationship: has_function CCO:F0008023 ! cell adhesion molecule binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001055 ! cortical cytoskeleton relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001896 ! apical part of cell relationship: transformation_of CCO:B0018212 ! EZRI_HUMAN [Term] id: CCO:B0034772 name: F261_HUMAN-Phosphoserine33 def: "Protein F261_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:P16118] comment: by PKA; By similarity xref: UniProtKB:P16118 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000392 ! 6-phosphofructo-2-kinase activity relationship: has_function CCO:F0000750 ! fructose-2,6-bisphosphate 2-phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001784 ! 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex relationship: transformation_of CCO:B0033471 ! F261_HUMAN [Term] id: CCO:B0034779 name: FABP4_HUMAN-Phosphotyrosine20 def: "Protein FABP4_HUMAN with the residue 20 substituted with Phosphotyrosine" [UniProtKB:P15090] comment: by Tyr-kinases; By similarity xref: UniProtKB:P15090 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0034068 ! FABP4_HUMAN [Term] id: CCO:B0034782 name: FABP7_HUMAN-N-acetylvaline2 def: "Protein FABP7_HUMAN with the residue 2 substituted with N-acetylvaline" [UniProtKB:O15540] comment: By similarity xref: UniProtKB:O15540 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034060 ! FABP7_HUMAN [Term] id: CCO:B0034783 name: FABPH_HUMAN-N-acetylvaline2 def: "Protein FABPH_HUMAN with the residue 2 substituted with N-acetylvaline" [UniProtKB:P05413] xref: UniProtKB:P05413 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034070 ! FABPH_HUMAN [Term] id: CCO:B0034784 name: FABPH_HUMAN-Phosphotyrosine20 def: "Protein FABPH_HUMAN with the residue 20 substituted with Phosphotyrosine" [UniProtKB:P05413] comment: by Tyr-kinases; By similarity xref: UniProtKB:P05413 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034070 ! FABPH_HUMAN [Term] id: CCO:B0034785 name: FCERB_HUMAN-Phosphotyrosine219 def: "Protein FCERB_HUMAN with the residue 219 substituted with Phosphotyrosine" [UniProtKB:Q01362] comment: By similarity xref: UniProtKB:Q01362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016650 ! FCERB_HUMAN [Term] id: CCO:B0034786 name: FCERB_HUMAN-Phosphotyrosine225 def: "Protein FCERB_HUMAN with the residue 225 substituted with Phosphotyrosine" [UniProtKB:Q01362] comment: By similarity xref: UniProtKB:Q01362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016650 ! FCERB_HUMAN [Term] id: CCO:B0034787 name: FCERB_HUMAN-Phosphoserine226 def: "Protein FCERB_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:Q01362] comment: By similarity xref: UniProtKB:Q01362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016650 ! FCERB_HUMAN [Term] id: CCO:B0034788 name: FCERB_HUMAN-Phosphotyrosine229 def: "Protein FCERB_HUMAN with the residue 229 substituted with Phosphotyrosine" [UniProtKB:Q01362] comment: By similarity xref: UniProtKB:Q01362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0004196 ! IgE binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001498 ! Fc-epsilon receptor I complex relationship: transformation_of CCO:B0016650 ! FCERB_HUMAN [Term] id: CCO:B0034789 name: FINC_HUMAN-Pyrrolidone carboxylic acid32 def: "Protein FINC_HUMAN with the residue 32 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P02751] xref: UniProtKB:P02751 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031949 ! FINC_HUMAN [Term] id: CCO:B0034790 name: FINC_HUMAN-Sulfotyrosine876 def: "Protein FINC_HUMAN with the residue 876 substituted with Sulfotyrosine" [UniProtKB:P02751] comment: Potential xref: UniProtKB:P02751 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031949 ! FINC_HUMAN [Term] id: CCO:B0034791 name: FINC_HUMAN-Sulfotyrosine881 def: "Protein FINC_HUMAN with the residue 881 substituted with Sulfotyrosine" [UniProtKB:P02751] comment: Potential xref: UniProtKB:P02751 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031949 ! FINC_HUMAN [Term] id: CCO:B0034792 name: FINC_HUMAN-Phosphoserine2384 def: "Protein FINC_HUMAN with the residue 2384 substituted with Phosphoserine" [UniProtKB:P02751] xref: UniProtKB:P02751 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031949 ! FINC_HUMAN [Term] id: CCO:B0034793 name: FOXA1_HUMAN-Phosphothreonine344 def: "Protein FOXA1_HUMAN with the residue 344 substituted with Phosphothreonine" [UniProtKB:P55317] comment: By similarity xref: UniProtKB:P55317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0031624 ! FOXA1_HUMAN [Term] id: CCO:B0034794 name: FOXC2_HUMAN-Phosphoserine219 def: "Protein FOXC2_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0034795 name: FOXC2_HUMAN-Phosphoserine232 def: "Protein FOXC2_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004674 ! chromatin DNA binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0034796 name: FOXC2_HUMAN-Phosphoserine240 def: "Protein FOXC2_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0034797 name: FOXO1_HUMAN-Phosphothreonine24 def: "Protein FOXO1_HUMAN with the residue 24 substituted with Phosphothreonine" [UniProtKB:Q12778] comment: by PKB/AKT1; xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034798 name: FOXO1_HUMAN-Phosphoserine256 def: "Protein FOXO1_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q12778] comment: by PKB/AKT1; xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034799 name: FOXO1_HUMAN-Phosphoserine319 def: "Protein FOXO1_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q12778] comment: by PKB/AKT1; xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034800 name: FOXO1_HUMAN-Phosphoserine329 def: "Protein FOXO1_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q12778] comment: by DYRK1A; xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034801 name: FOXO1_HUMAN-Phosphothreonine467 def: "Protein FOXO1_HUMAN with the residue 467 substituted with Phosphothreonine" [UniProtKB:Q12778] comment: By similarity xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034802 name: FOXO1_HUMAN-Phosphoserine468 def: "Protein FOXO1_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:Q12778] comment: By similarity xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034803 name: FOXO1_HUMAN-Phosphoserine505 def: "Protein FOXO1_HUMAN with the residue 505 substituted with Phosphoserine" [UniProtKB:Q12778] xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034804 name: FOXO1_HUMAN-Phosphoserine509 def: "Protein FOXO1_HUMAN with the residue 509 substituted with Phosphoserine" [UniProtKB:Q12778] xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0034805 name: FOXO6_HUMAN-Phosphoserine184 def: "Protein FOXO6_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:A8MYZ6] comment: By similarity xref: UniProtKB:A8MYZ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0033027 ! FOXO6_HUMAN [Term] id: CCO:B0034806 name: FPR1_HUMAN-Phosphoserine328 def: "Protein FPR1_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034807 name: FPR1_HUMAN-Phosphothreonine329 def: "Protein FPR1_HUMAN with the residue 329 substituted with Phosphothreonine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034808 name: FPR1_HUMAN-Phosphothreonine331 def: "Protein FPR1_HUMAN with the residue 331 substituted with Phosphothreonine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034809 name: FPR1_HUMAN-Phosphoserine332 def: "Protein FPR1_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034810 name: FPR1_HUMAN-Phosphothreonine334 def: "Protein FPR1_HUMAN with the residue 334 substituted with Phosphothreonine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034811 name: FPR1_HUMAN-Phosphothreonine336 def: "Protein FPR1_HUMAN with the residue 336 substituted with Phosphothreonine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034812 name: FPR1_HUMAN-Phosphoserine338 def: "Protein FPR1_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034813 name: FPR1_HUMAN-Phosphothreonine339 def: "Protein FPR1_HUMAN with the residue 339 substituted with Phosphothreonine" [UniProtKB:P21462] comment: Potential xref: UniProtKB:P21462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0027200 ! FPR1_HUMAN [Term] id: CCO:B0034814 name: FRIH_HUMAN-Phosphoserine179 def: "Protein FRIH_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:P02794] xref: UniProtKB:P02794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000743 ! ferroxidase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001778 ! ferric iron binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000525 ! ferritin complex relationship: transformation_of CCO:B0033704 ! FRIH_HUMAN [Term] id: CCO:B0034815 name: G3BP1_HUMAN-Phosphoserine149 def: "Protein G3BP1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034816 name: G3BP1_HUMAN-Phosphoserine230 def: "Protein G3BP1_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034817 name: G3BP1_HUMAN-Phosphoserine231 def: "Protein G3BP1_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034818 name: G3BP1_HUMAN-Phosphoserine232 def: "Protein G3BP1_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034819 name: G3BP1_HUMAN-Phosphothreonine268 def: "Protein G3BP1_HUMAN with the residue 268 substituted with Phosphothreonine" [UniProtKB:Q13283] comment: By similarity xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034820 name: G3BP1_HUMAN-Omega-N-methylated arginine435 def: "Protein G3BP1_HUMAN with the residue 435 substituted with Omega-N-methylated arginine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034821 name: G3BP1_HUMAN-Omega-N-methylated arginine447 def: "Protein G3BP1_HUMAN with the residue 447 substituted with Omega-N-methylated arginine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034822 name: G3BP1_HUMAN-Omega-N-methylated arginine460 def: "Protein G3BP1_HUMAN with the residue 460 substituted with Omega-N-methylated arginine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034823 name: G3BP1_HUMAN-Omega-N-methylated arginine465 def: "Protein G3BP1_HUMAN with the residue 465 substituted with Omega-N-methylated arginine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0034824 name: G3BP2_HUMAN-Phosphoserine141 def: "Protein G3BP2_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q9UN86] xref: UniProtKB:Q9UN86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028327 ! G3BP2_HUMAN [Term] id: CCO:B0034825 name: G3BP2_HUMAN-Phosphoserine149 def: "Protein G3BP2_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q9UN86] xref: UniProtKB:Q9UN86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028327 ! G3BP2_HUMAN [Term] id: CCO:B0034826 name: G3BP2_HUMAN-Phosphoserine225 def: "Protein G3BP2_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q9UN86] comment: By similarity xref: UniProtKB:Q9UN86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0028327 ! G3BP2_HUMAN [Term] id: CCO:B0034827 name: G3BP2_HUMAN-Phosphothreonine227 def: "Protein G3BP2_HUMAN with the residue 227 substituted with Phosphothreonine" [UniProtKB:Q9UN86] xref: UniProtKB:Q9UN86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028327 ! G3BP2_HUMAN [Term] id: CCO:B0034828 name: G3BP2_HUMAN-Omega-N-methylated arginine457 def: "Protein G3BP2_HUMAN with the residue 457 substituted with Omega-N-methylated arginine" [UniProtKB:Q9UN86] xref: UniProtKB:Q9UN86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028327 ! G3BP2_HUMAN [Term] id: CCO:B0034829 name: G3BP2_HUMAN-Omega-N-methylated arginine468 def: "Protein G3BP2_HUMAN with the residue 468 substituted with Omega-N-methylated arginine" [UniProtKB:Q9UN86] xref: UniProtKB:Q9UN86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028327 ! G3BP2_HUMAN [Term] id: CCO:B0034837 name: GHRL_HUMAN-Leucine amide98 def: "Protein GHRL_HUMAN with the residue 98 substituted with Leucine amide" [UniProtKB:Q9UBU3] comment: By similarity xref: UniProtKB:Q9UBU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033567 ! GHRL_HUMAN [Term] id: CCO:B0034838 name: GPR64_HUMAN-Phosphoserine1010 def: "Protein GPR64_HUMAN with the residue 1010 substituted with Phosphoserine" [UniProtKB:Q8IZP9] xref: UniProtKB:Q8IZP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033418 ! GPR64_HUMAN [Term] id: CCO:B0034843 name: GSK3B_HUMAN-Phosphothreonine7 def: "Protein GSK3B_HUMAN with the residue 7 substituted with Phosphothreonine" [UniProtKB:P49841] comment: By similarity xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034844 name: GSK3B_HUMAN-Phosphoserine9 def: "Protein GSK3B_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P49841] comment: by PKB/AKT1; xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034845 name: GSK3B_HUMAN-Phosphoserine215 def: "Protein GSK3B_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:P49841] comment: By similarity xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000257 ! p53 binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001063 ! glycogen synthase kinase 3 activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0007673 ! tau-protein kinase activity relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001067 ! beta-catenin destruction complex relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034846 name: GSK3B_HUMAN-Phosphotyrosine216 def: "Protein GSK3B_HUMAN with the residue 216 substituted with Phosphotyrosine" [UniProtKB:P49841] xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034847 name: GSK3B_HUMAN-Phosphoserine219 def: "Protein GSK3B_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:P49841] comment: By similarity xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034848 name: GSK3B_HUMAN-Phosphoserine389 def: "Protein GSK3B_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:P49841] comment: By similarity xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034849 name: GSK3B_HUMAN-Phosphothreonine390 def: "Protein GSK3B_HUMAN with the residue 390 substituted with Phosphothreonine" [UniProtKB:P49841] xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034850 name: GSK3B_HUMAN-Phosphothreonine395 def: "Protein GSK3B_HUMAN with the residue 395 substituted with Phosphothreonine" [UniProtKB:P49841] comment: By similarity xref: UniProtKB:P49841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:B0034851 name: GTPB1_HUMAN-Phosphoserine12 def: "Protein GTPB1_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:O00178] comment: By similarity xref: UniProtKB:O00178 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020855 ! GTPB1_HUMAN [Term] id: CCO:B0034852 name: GTPB1_HUMAN-Phosphoserine25 def: "Protein GTPB1_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:O00178] comment: By similarity xref: UniProtKB:O00178 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020855 ! GTPB1_HUMAN [Term] id: CCO:B0034853 name: GTPB1_HUMAN-Phosphoserine44 def: "Protein GTPB1_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:O00178] xref: UniProtKB:O00178 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020855 ! GTPB1_HUMAN [Term] id: CCO:B0034854 name: GTPB1_HUMAN-Phosphoserine47 def: "Protein GTPB1_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:O00178] xref: UniProtKB:O00178 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020855 ! GTPB1_HUMAN [Term] id: CCO:B0034856 name: HIRA_HUMAN-Phosphothreonine555 def: "Protein HIRA_HUMAN with the residue 555 substituted with Phosphothreonine" [UniProtKB:P54198] comment: by CDK2; xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0034857 name: HIRA_HUMAN-Phosphoserine687 def: "Protein HIRA_HUMAN with the residue 687 substituted with Phosphoserine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0034859 name: HSF1_HUMAN-Phosphoserine303 def: "Protein HSF1_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:Q00613] xref: UniProtKB:Q00613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:B0034860 name: HSF1_HUMAN-Phosphoserine307 def: "Protein HSF1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q00613] xref: UniProtKB:Q00613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:B0034861 name: HSF1_HUMAN-Phosphothreonine323 def: "Protein HSF1_HUMAN with the residue 323 substituted with Phosphothreonine" [UniProtKB:Q00613] xref: UniProtKB:Q00613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:B0034862 name: HSF1_HUMAN-Phosphoserine363 def: "Protein HSF1_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q00613] xref: UniProtKB:Q00613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:B0034863 name: HSPB8_HUMAN-Phosphothreonine63 def: "Protein HSPB8_HUMAN with the residue 63 substituted with Phosphothreonine" [UniProtKB:Q9UJY1] comment: by PKC; in vitro; xref: UniProtKB:Q9UJY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024107 ! HSPB8_HUMAN [Term] id: CCO:B0034864 name: I12R2_HUMAN-Phosphotyrosine800 def: "Protein I12R2_HUMAN with the residue 800 substituted with Phosphotyrosine" [UniProtKB:Q99665] xref: UniProtKB:Q99665 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001254 ! interleukin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0034147 ! I12R2_HUMAN [Term] id: CCO:B0034865 name: I2C4_HUMAN-Phosphoserine798 def: "Protein I2C4_HUMAN with the residue 798 substituted with Phosphoserine" [UniProtKB:Q9HCK5] xref: UniProtKB:Q9HCK5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016055 ! I2C4_HUMAN [Term] id: CCO:B0034866 name: ICK_HUMAN-Phosphothreonine14 def: "Protein ICK_HUMAN with the residue 14 substituted with Phosphothreonine" [UniProtKB:Q9UPZ9] comment: By similarity xref: UniProtKB:Q9UPZ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018166 ! ICK_HUMAN [Term] id: CCO:B0034867 name: ICK_HUMAN-Phosphotyrosine15 def: "Protein ICK_HUMAN with the residue 15 substituted with Phosphotyrosine" [UniProtKB:Q9UPZ9] comment: By similarity xref: UniProtKB:Q9UPZ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018166 ! ICK_HUMAN [Term] id: CCO:B0034868 name: ICK_HUMAN-Phosphothreonine157 def: "Protein ICK_HUMAN with the residue 157 substituted with Phosphothreonine" [UniProtKB:Q9UPZ9] xref: UniProtKB:Q9UPZ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0018166 ! ICK_HUMAN [Term] id: CCO:B0034869 name: ICK_HUMAN-Phosphotyrosine159 def: "Protein ICK_HUMAN with the residue 159 substituted with Phosphotyrosine" [UniProtKB:Q9UPZ9] xref: UniProtKB:Q9UPZ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018166 ! ICK_HUMAN [Term] id: CCO:B0034870 name: IFNG_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein IFNG_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P01579] xref: UniProtKB:P01579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031813 ! IFNG_HUMAN [Term] id: CCO:B0034872 name: IL3RB_HUMAN-Phosphotyrosine766 def: "Protein IL3RB_HUMAN with the residue 766 substituted with Phosphotyrosine" [UniProtKB:P32927] comment: By similarity xref: UniProtKB:P32927 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001254 ! interleukin receptor activity relationship: has_function CCO:F0001259 ! interleukin-3 receptor activity relationship: has_function CCO:F0001261 ! interleukin-5 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001018 ! granulocyte macrophage colony-stimulating factor receptor complex relationship: transformation_of CCO:B0025042 ! IL3RB_HUMAN [Term] id: CCO:B0034873 name: IL6RB_HUMAN-Phosphoserine667 def: "Protein IL6RB_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:P40189] xref: UniProtKB:P40189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025184 ! IL6RB_HUMAN [Term] id: CCO:B0034874 name: IL6RB_HUMAN-Phosphoserine782 def: "Protein IL6RB_HUMAN with the residue 782 substituted with Phosphoserine" [UniProtKB:P40189] xref: UniProtKB:P40189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025184 ! IL6RB_HUMAN [Term] id: CCO:B0034875 name: IL6RB_HUMAN-Phosphoserine820 def: "Protein IL6RB_HUMAN with the residue 820 substituted with Phosphoserine" [UniProtKB:P40189] xref: UniProtKB:P40189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025184 ! IL6RB_HUMAN [Term] id: CCO:B0034876 name: IL6RB_HUMAN-Phosphoserine829 def: "Protein IL6RB_HUMAN with the residue 829 substituted with Phosphoserine" [UniProtKB:P40189] xref: UniProtKB:P40189 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025184 ! IL6RB_HUMAN [Term] id: CCO:B0034879 name: IQGA1_HUMAN-Phosphoserine2 def: "Protein IQGA1_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P46940] xref: UniProtKB:P46940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:B0034880 name: IQGA1_HUMAN-Phosphotyrosine172 def: "Protein IQGA1_HUMAN with the residue 172 substituted with Phosphotyrosine" [UniProtKB:P46940] xref: UniProtKB:P46940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:B0034881 name: IQGA1_HUMAN-Phosphoserine330 def: "Protein IQGA1_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P46940] xref: UniProtKB:P46940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:B0034882 name: IQGA1_HUMAN-Phosphoserine1441 def: "Protein IQGA1_HUMAN with the residue 1441 substituted with Phosphoserine" [UniProtKB:P46940] comment: by PKC; Probable xref: UniProtKB:P46940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:B0034883 name: IQGA1_HUMAN-Phosphoserine1443 def: "Protein IQGA1_HUMAN with the residue 1443 substituted with Phosphoserine" [UniProtKB:P46940] comment: by PKC; xref: UniProtKB:P46940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:B0034884 name: ITB1_HUMAN-Phosphotyrosine783 def: "Protein ITB1_HUMAN with the residue 783 substituted with Phosphotyrosine" [UniProtKB:P05556] xref: UniProtKB:P05556 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001300 ! neuromuscular junction relationship: located_in CCO:C0001638 ! sarcolemma relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0033138 ! ITB1_HUMAN [Term] id: CCO:B0034885 name: ITB2_HUMAN-Pyrrolidone carboxylic acid23 def: "Protein ITB2_HUMAN with the residue 23 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P05107] xref: UniProtKB:P05107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033122 ! ITB2_HUMAN [Term] id: CCO:B0034886 name: ITB2_HUMAN-Phosphoserine745 def: "Protein ITB2_HUMAN with the residue 745 substituted with Phosphoserine" [UniProtKB:P05107] comment: by PKC; xref: UniProtKB:P05107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033122 ! ITB2_HUMAN [Term] id: CCO:B0034887 name: ITB2_HUMAN-Phosphoserine756 def: "Protein ITB2_HUMAN with the residue 756 substituted with Phosphoserine" [UniProtKB:P05107] xref: UniProtKB:P05107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033122 ! ITB2_HUMAN [Term] id: CCO:B0034888 name: ITB2_HUMAN-Phosphothreonine758 def: "Protein ITB2_HUMAN with the residue 758 substituted with Phosphothreonine" [UniProtKB:P05107] comment: by PKC; in vitro; xref: UniProtKB:P05107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033122 ! ITB2_HUMAN [Term] id: CCO:B0034889 name: ITB2_HUMAN-Phosphothreonine759 def: "Protein ITB2_HUMAN with the residue 759 substituted with Phosphothreonine" [UniProtKB:P05107] comment: Potential xref: UniProtKB:P05107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0033122 ! ITB2_HUMAN [Term] id: CCO:B0034890 name: ITB2_HUMAN-Phosphothreonine760 def: "Protein ITB2_HUMAN with the residue 760 substituted with Phosphothreonine" [UniProtKB:P05107] comment: by PKC/PRKCA; in vitro; xref: UniProtKB:P05107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033122 ! ITB2_HUMAN [Term] id: CCO:B0034891 name: ITB3_HUMAN-Phosphotyrosine773 def: "Protein ITB3_HUMAN with the residue 773 substituted with Phosphotyrosine" [UniProtKB:P05106] xref: UniProtKB:P05106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:B0034892 name: ITB3_HUMAN-Phosphothreonine779 def: "Protein ITB3_HUMAN with the residue 779 substituted with Phosphothreonine" [UniProtKB:P05106] comment: by PDPK1 and PKB/AKT1; in vitro; xref: UniProtKB:P05106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:B0034893 name: ITB3_HUMAN-Phosphotyrosine785 def: "Protein ITB3_HUMAN with the residue 785 substituted with Phosphotyrosine" [UniProtKB:P05106] xref: UniProtKB:P05106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:B0034894 name: ITB4_HUMAN-Phosphoserine1084 def: "Protein ITB4_HUMAN with the residue 1084 substituted with Phosphoserine" [UniProtKB:P16144] xref: UniProtKB:P16144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0033114 ! ITB4_HUMAN [Term] id: CCO:B0034895 name: ITB4_HUMAN-Phosphotyrosine1207 def: "Protein ITB4_HUMAN with the residue 1207 substituted with Phosphotyrosine" [UniProtKB:P16144] xref: UniProtKB:P16144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033114 ! ITB4_HUMAN [Term] id: CCO:B0034896 name: ITB4_HUMAN-Phosphothreonine1530 def: "Protein ITB4_HUMAN with the residue 1530 substituted with Phosphothreonine" [UniProtKB:P16144] xref: UniProtKB:P16144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033114 ! ITB4_HUMAN [Term] id: CCO:B0034897 name: ITB7_HUMAN-Phosphotyrosine778 def: "Protein ITB7_HUMAN with the residue 778 substituted with Phosphotyrosine" [UniProtKB:P26010] comment: by Tyr-kinases; By similarity xref: UniProtKB:P26010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033137 ! ITB7_HUMAN [Term] id: CCO:B0034942 name: K0174_HUMAN-Phosphotyrosine43 def: "Protein K0174_HUMAN with the residue 43 substituted with Phosphotyrosine" [UniProtKB:P53990] xref: UniProtKB:P53990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: transformation_of CCO:B0026635 ! K0174_HUMAN [Term] id: CCO:B0034943 name: K22E_HUMAN-Phosphoserine62 def: "Protein K22E_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:P35908] comment: By similarity xref: UniProtKB:P35908 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0021657 ! K22E_HUMAN [Term] id: CCO:B0034948 name: K2C4_HUMAN-Phosphoserine51 def: "Protein K2C4_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P19013] comment: By similarity xref: UniProtKB:P19013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0021644 ! K2C4_HUMAN [Term] id: CCO:B0034952 name: K6PF_HUMAN-Phosphothreonine2 def: "Protein K6PF_HUMAN with the residue 2 substituted with Phosphothreonine" [UniProtKB:P08237] xref: UniProtKB:P08237 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000391 ! 6-phosphofructokinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001906 ! phosphofructokinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000495 ! 6-phosphofructokinase complex relationship: transformation_of CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:B0034953 name: K6PF_HUMAN-Phosphoserine775 def: "Protein K6PF_HUMAN with the residue 775 substituted with Phosphoserine" [UniProtKB:P08237] comment: By similarity xref: UniProtKB:P08237 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:B0034954 name: K6PL_HUMAN-Phosphotyrosine633 def: "Protein K6PL_HUMAN with the residue 633 substituted with Phosphotyrosine" [UniProtKB:P17858] xref: UniProtKB:P17858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000391 ! 6-phosphofructokinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000495 ! 6-phosphofructokinase complex relationship: transformation_of CCO:B0034104 ! K6PL_HUMAN [Term] id: CCO:B0034955 name: K6PL_HUMAN-Phosphotyrosine640 def: "Protein K6PL_HUMAN with the residue 640 substituted with Phosphotyrosine" [UniProtKB:P17858] comment: By similarity xref: UniProtKB:P17858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034104 ! K6PL_HUMAN [Term] id: CCO:B0034960 name: KAP1_HUMAN-N-acetylalanine2 def: "Protein KAP1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P31321] comment: Probable xref: UniProtKB:P31321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021337 ! KAP1_HUMAN [Term] id: CCO:B0034961 name: KAP1_HUMAN-Nitrated tyrosine21 def: "Protein KAP1_HUMAN with the residue 21 substituted with Nitrated tyrosine" [UniProtKB:P31321] xref: UniProtKB:P31321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0004464 ! cAMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: transformation_of CCO:B0021337 ! KAP1_HUMAN [Term] id: CCO:B0034962 name: KAP2_HUMAN-N-acetylserine2 def: "Protein KAP2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P13861] comment: Probable xref: UniProtKB:P13861 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022455 ! KAP2_HUMAN [Term] id: CCO:B0034963 name: KAP2_HUMAN-Phosphothreonine54 def: "Protein KAP2_HUMAN with the residue 54 substituted with Phosphothreonine" [UniProtKB:P13861] xref: UniProtKB:P13861 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022455 ! KAP2_HUMAN [Term] id: CCO:B0034964 name: KAP2_HUMAN-Phosphoserine58 def: "Protein KAP2_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:P13861] xref: UniProtKB:P13861 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022455 ! KAP2_HUMAN [Term] id: CCO:B0034965 name: KAP2_HUMAN-Phosphoserine78 def: "Protein KAP2_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:P13861] xref: UniProtKB:P13861 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022455 ! KAP2_HUMAN [Term] id: CCO:B0034966 name: KAP2_HUMAN-Phosphoserine80 def: "Protein KAP2_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:P13861] xref: UniProtKB:P13861 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022455 ! KAP2_HUMAN [Term] id: CCO:B0034967 name: KAP2_HUMAN-Phosphoserine99 def: "Protein KAP2_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:P13861] comment: by PKA; xref: UniProtKB:P13861 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022455 ! KAP2_HUMAN [Term] id: CCO:B0034968 name: KAP3_HUMAN-N-acetylserine2 def: "Protein KAP3_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P31323] comment: Probable xref: UniProtKB:P31323 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022454 ! KAP3_HUMAN [Term] id: CCO:B0034969 name: KAP3_HUMAN-Phosphoserine114 def: "Protein KAP3_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:P31323] xref: UniProtKB:P31323 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0004464 ! cAMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: transformation_of CCO:B0022454 ! KAP3_HUMAN [Term] id: CCO:B0034970 name: KAPCA_HUMAN-Deamidated asparagine3 def: "Protein KAPCA_HUMAN with the residue 3 substituted with Deamidated asparagine" [UniProtKB:P17612] comment: By similarity xref: UniProtKB:P17612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:B0034971 name: KAPCA_HUMAN-Phosphoserine11 def: "Protein KAPCA_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P17612] comment: by autocatalysis; By similarity xref: UniProtKB:P17612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:B0034972 name: KAPCA_HUMAN-Phosphoserine140 def: "Protein KAPCA_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P17612] comment: By similarity xref: UniProtKB:P17612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:B0034973 name: KAPCA_HUMAN-Phosphothreonine196 def: "Protein KAPCA_HUMAN with the residue 196 substituted with Phosphothreonine" [UniProtKB:P17612] comment: By similarity xref: UniProtKB:P17612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:B0034974 name: KAPCA_HUMAN-Phosphothreonine198 def: "Protein KAPCA_HUMAN with the residue 198 substituted with Phosphothreonine" [UniProtKB:P17612] xref: UniProtKB:P17612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:B0034975 name: KAPCA_HUMAN-Phosphothreonine202 def: "Protein KAPCA_HUMAN with the residue 202 substituted with Phosphothreonine" [UniProtKB:P17612] xref: UniProtKB:P17612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001058 ! cAMP-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: transformation_of CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:B0034976 name: KAPCA_HUMAN-Phosphoserine339 def: "Protein KAPCA_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:P17612] xref: UniProtKB:P17612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:B0034977 name: KAPCB_HUMAN-Deamidated asparagine3 def: "Protein KAPCB_HUMAN with the residue 3 substituted with Deamidated asparagine" [UniProtKB:P22694] comment: By similarity xref: UniProtKB:P22694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018534 ! KAPCB_HUMAN [Term] id: CCO:B0034978 name: KAPCB_HUMAN-Phosphotyrosine69 def: "Protein KAPCB_HUMAN with the residue 69 substituted with Phosphotyrosine" [UniProtKB:P22694] comment: By similarity xref: UniProtKB:P22694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001058 ! cAMP-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: transformation_of CCO:B0018534 ! KAPCB_HUMAN [Term] id: CCO:B0034979 name: KAPCB_HUMAN-Phosphothreonine198 def: "Protein KAPCB_HUMAN with the residue 198 substituted with Phosphothreonine" [UniProtKB:P22694] comment: By similarity xref: UniProtKB:P22694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018534 ! KAPCB_HUMAN [Term] id: CCO:B0034980 name: KAPCB_HUMAN-Phosphoserine339 def: "Protein KAPCB_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:P22694] comment: By similarity xref: UniProtKB:P22694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018534 ! KAPCB_HUMAN [Term] id: CCO:B0034981 name: KAPCG_HUMAN-Phosphothreonine198 def: "Protein KAPCG_HUMAN with the residue 198 substituted with Phosphothreonine" [UniProtKB:P22612] comment: by autocatalysis; By similarity xref: UniProtKB:P22612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018532 ! KAPCG_HUMAN [Term] id: CCO:B0034982 name: KAPCG_HUMAN-Phosphoserine339 def: "Protein KAPCG_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:P22612] comment: by autocatalysis; By similarity xref: UniProtKB:P22612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018532 ! KAPCG_HUMAN [Term] id: CCO:B0034983 name: KC1D_HUMAN-Phosphoserine331 def: "Protein KC1D_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:P48730] xref: UniProtKB:P48730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017481 ! KC1D_HUMAN [Term] id: CCO:B0034984 name: KC1D_HUMAN-Phosphoserine350 def: "Protein KC1D_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:P48730] xref: UniProtKB:P48730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017481 ! KC1D_HUMAN [Term] id: CCO:B0034985 name: KC1D_HUMAN-Phosphoserine382 def: "Protein KC1D_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:P48730] xref: UniProtKB:P48730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017481 ! KC1D_HUMAN [Term] id: CCO:B0034986 name: KCC1A_HUMAN-Phosphothreonine177 def: "Protein KCC1A_HUMAN with the residue 177 substituted with Phosphothreonine" [UniProtKB:Q14012] comment: by CaMKK1 and CaMKK2; xref: UniProtKB:Q14012 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0016556 ! KCC1A_HUMAN [Term] id: CCO:B0034989 name: KCC2A_HUMAN-Phosphotyrosine13 def: "Protein KCC2A_HUMAN with the residue 13 substituted with Phosphotyrosine" [UniProtKB:Q9UQM7] comment: By similarity xref: UniProtKB:Q9UQM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016569 ! KCC2A_HUMAN [Term] id: CCO:B0034990 name: KCC2A_HUMAN-Phosphoserine25 def: "Protein KCC2A_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q9UQM7] comment: By similarity xref: UniProtKB:Q9UQM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016569 ! KCC2A_HUMAN [Term] id: CCO:B0034991 name: KCC2A_HUMAN-Phosphoserine275 def: "Protein KCC2A_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q9UQM7] comment: By similarity xref: UniProtKB:Q9UQM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016569 ! KCC2A_HUMAN [Term] id: CCO:B0034992 name: KCC2A_HUMAN-Phosphothreonine286 def: "Protein KCC2A_HUMAN with the residue 286 substituted with Phosphothreonine" [UniProtKB:Q9UQM7] comment: by autocatalysis; By similarity xref: UniProtKB:Q9UQM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0016569 ! KCC2A_HUMAN [Term] id: CCO:B0034993 name: KCC2A_HUMAN-Phosphoserine333 def: "Protein KCC2A_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q9UQM7] comment: By similarity xref: UniProtKB:Q9UQM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016569 ! KCC2A_HUMAN [Term] id: CCO:B0034994 name: KCC2A_HUMAN-Phosphothreonine334 def: "Protein KCC2A_HUMAN with the residue 334 substituted with Phosphothreonine" [UniProtKB:Q9UQM7] comment: By similarity xref: UniProtKB:Q9UQM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016569 ! KCC2A_HUMAN [Term] id: CCO:B0034995 name: KCC2A_HUMAN-Phosphothreonine337 def: "Protein KCC2A_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:Q9UQM7] comment: By similarity xref: UniProtKB:Q9UQM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016569 ! KCC2A_HUMAN [Term] id: CCO:B0034996 name: KCC4_HUMAN-Phosphoserine12 def: "Protein KCC4_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q16566] comment: by autocatalysis; xref: UniProtKB:Q16566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016540 ! KCC4_HUMAN [Term] id: CCO:B0034997 name: KCC4_HUMAN-Phosphoserine13 def: "Protein KCC4_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:Q16566] comment: by autocatalysis; xref: UniProtKB:Q16566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016540 ! KCC4_HUMAN [Term] id: CCO:B0034998 name: KCC4_HUMAN-Phosphothreonine200 def: "Protein KCC4_HUMAN with the residue 200 substituted with Phosphothreonine" [UniProtKB:Q16566] xref: UniProtKB:Q16566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016540 ! KCC4_HUMAN [Term] id: CCO:B0034999 name: KCC4_HUMAN-Phosphoserine336 def: "Protein KCC4_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:Q16566] comment: by autocatalysis; xref: UniProtKB:Q16566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0016540 ! KCC4_HUMAN [Term] id: CCO:B0035000 name: KCC4_HUMAN-Phosphoserine341 def: "Protein KCC4_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q16566] xref: UniProtKB:Q16566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016540 ! KCC4_HUMAN [Term] id: CCO:B0035001 name: KCC4_HUMAN-Phosphoserine360 def: "Protein KCC4_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q16566] xref: UniProtKB:Q16566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016540 ! KCC4_HUMAN [Term] id: CCO:B0035012 name: KCRB_HUMAN-Phosphotyrosine39 def: "Protein KCRB_HUMAN with the residue 39 substituted with Phosphotyrosine" [UniProtKB:P12277] comment: By similarity xref: UniProtKB:P12277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015997 ! KCRB_HUMAN [Term] id: CCO:B0035013 name: KCRB_HUMAN-Phosphotyrosine125 def: "Protein KCRB_HUMAN with the residue 125 substituted with Phosphotyrosine" [UniProtKB:P12277] comment: By similarity xref: UniProtKB:P12277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015997 ! KCRB_HUMAN [Term] id: CCO:B0035014 name: KCRB_HUMAN-Phosphoserine164 def: "Protein KCRB_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:P12277] comment: By similarity xref: UniProtKB:P12277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000583 ! creatine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0015997 ! KCRB_HUMAN [Term] id: CCO:B0035018 name: KI18A_HUMAN-Phosphothreonine706 def: "Protein KI18A_HUMAN with the residue 706 substituted with Phosphothreonine" [UniProtKB:Q8NI77] xref: UniProtKB:Q8NI77 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026171 ! KI18A_HUMAN [Term] id: CCO:B0035039 name: KPCB_HUMAN-N-acetylalanine2 def: "Protein KPCB_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P05771] xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035040 name: KPCB_HUMAN-Phosphoserine16 def: "Protein KPCB_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:P05771] comment: by autocatalysis; Potential xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035041 name: KPCB_HUMAN-Phosphothreonine17 def: "Protein KPCB_HUMAN with the residue 17 substituted with Phosphothreonine" [UniProtKB:P05771] comment: by autocatalysis; Potential xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035042 name: KPCB_HUMAN-Phosphotyrosine195 def: "Protein KPCB_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:P05771] comment: By similarity xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035043 name: KPCB_HUMAN-Phosphothreonine314 def: "Protein KPCB_HUMAN with the residue 314 substituted with Phosphothreonine" [UniProtKB:P05771] comment: by autocatalysis; Potential xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035044 name: KPCB_HUMAN-Phosphothreonine324 def: "Protein KPCB_HUMAN with the residue 324 substituted with Phosphothreonine" [UniProtKB:P05771] comment: by autocatalysis; Potential xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035045 name: KPCB_HUMAN-Phosphothreonine500 def: "Protein KPCB_HUMAN with the residue 500 substituted with Phosphothreonine" [UniProtKB:P05771] xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035046 name: KPCB_HUMAN-Phosphothreonine504 def: "Protein KPCB_HUMAN with the residue 504 substituted with Phosphothreonine" [UniProtKB:P05771] xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035047 name: KPCB_HUMAN-Phosphothreonine635 def: "Protein KPCB_HUMAN with the residue 635 substituted with Phosphothreonine" [UniProtKB:P05771] comment: by autocatalysis; xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035048 name: KPCB_HUMAN-Phosphothreonine642 def: "Protein KPCB_HUMAN with the residue 642 substituted with Phosphothreonine" [UniProtKB:P05771] xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035049 name: KPCB_HUMAN-Phosphoserine661 def: "Protein KPCB_HUMAN with the residue 661 substituted with Phosphoserine" [UniProtKB:P05771] comment: by autocatalysis; xref: UniProtKB:P05771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025045 ! KPCB_HUMAN [Term] id: CCO:B0035050 name: KPCE_HUMAN-Phosphoserine337 def: "Protein KPCE_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q02156] comment: By similarity xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0035051 name: KPCE_HUMAN-Phosphothreonine349 def: "Protein KPCE_HUMAN with the residue 349 substituted with Phosphothreonine" [UniProtKB:Q02156] comment: By similarity xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0035052 name: KPCE_HUMAN-Phosphothreonine566 def: "Protein KPCE_HUMAN with the residue 566 substituted with Phosphothreonine" [UniProtKB:Q02156] comment: by PDPK1; xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0035053 name: KPCE_HUMAN-Phosphothreonine703 def: "Protein KPCE_HUMAN with the residue 703 substituted with Phosphothreonine" [UniProtKB:Q02156] comment: by autocatalysis; Potential xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0035054 name: KPCE_HUMAN-Phosphothreonine710 def: "Protein KPCE_HUMAN with the residue 710 substituted with Phosphothreonine" [UniProtKB:Q02156] comment: by autocatalysis; Potential xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0035055 name: KPCE_HUMAN-Phosphoserine729 def: "Protein KPCE_HUMAN with the residue 729 substituted with Phosphoserine" [UniProtKB:Q02156] comment: by autocatalysis; xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0035056 name: KPCG_HUMAN-Phosphotyrosine195 def: "Protein KPCG_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:P05129] xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035057 name: KPCG_HUMAN-Phosphotyrosine312 def: "Protein KPCG_HUMAN with the residue 312 substituted with Phosphotyrosine" [UniProtKB:P05129] comment: By similarity xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035058 name: KPCG_HUMAN-Phosphoserine322 def: "Protein KPCG_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:P05129] comment: By similarity xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035059 name: KPCG_HUMAN-Phosphoserine330 def: "Protein KPCG_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P05129] comment: By similarity xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035060 name: KPCG_HUMAN-Phosphothreonine514 def: "Protein KPCG_HUMAN with the residue 514 substituted with Phosphothreonine" [UniProtKB:P05129] comment: By similarity xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035061 name: KPCG_HUMAN-Phosphothreonine518 def: "Protein KPCG_HUMAN with the residue 518 substituted with Phosphothreonine" [UniProtKB:P05129] comment: By similarity xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035062 name: KPCG_HUMAN-Phosphothreonine648 def: "Protein KPCG_HUMAN with the residue 648 substituted with Phosphothreonine" [UniProtKB:P05129] comment: by autocatalysis; Potential xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035063 name: KPCG_HUMAN-Phosphothreonine655 def: "Protein KPCG_HUMAN with the residue 655 substituted with Phosphothreonine" [UniProtKB:P05129] comment: by autocatalysis; Potential xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035064 name: KPCG_HUMAN-Phosphoserine687 def: "Protein KPCG_HUMAN with the residue 687 substituted with Phosphoserine" [UniProtKB:P05129] comment: By similarity xref: UniProtKB:P05129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0001005 ! dendrite relationship: transformation_of CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:B0035068 name: KPCT_HUMAN-Phosphothreonine219 def: "Protein KPCT_HUMAN with the residue 219 substituted with Phosphothreonine" [UniProtKB:Q04759] comment: by autocatalysis; xref: UniProtKB:Q04759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025053 ! KPCT_HUMAN [Term] id: CCO:B0035069 name: KPCT_HUMAN-Phosphothreonine538 def: "Protein KPCT_HUMAN with the residue 538 substituted with Phosphothreonine" [UniProtKB:Q04759] xref: UniProtKB:Q04759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025053 ! KPCT_HUMAN [Term] id: CCO:B0035070 name: KPCT_HUMAN-Phosphoserine676 def: "Protein KPCT_HUMAN with the residue 676 substituted with Phosphoserine" [UniProtKB:Q04759] xref: UniProtKB:Q04759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025053 ! KPCT_HUMAN [Term] id: CCO:B0035071 name: KPCT_HUMAN-Phosphoserine685 def: "Protein KPCT_HUMAN with the residue 685 substituted with Phosphoserine" [UniProtKB:Q04759] xref: UniProtKB:Q04759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025053 ! KPCT_HUMAN [Term] id: CCO:B0035072 name: KPCT_HUMAN-Phosphoserine695 def: "Protein KPCT_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:Q04759] xref: UniProtKB:Q04759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0025053 ! KPCT_HUMAN [Term] id: CCO:B0035077 name: L1CAM_HUMAN-Phosphoserine1163 def: "Protein L1CAM_HUMAN with the residue 1163 substituted with Phosphoserine" [UniProtKB:P32004] xref: UniProtKB:P32004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029795 ! L1CAM_HUMAN [Term] id: CCO:B0035078 name: L1CAM_HUMAN-Phosphoserine1190 def: "Protein L1CAM_HUMAN with the residue 1190 substituted with Phosphoserine" [UniProtKB:P32004] xref: UniProtKB:P32004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029795 ! L1CAM_HUMAN [Term] id: CCO:B0035079 name: L1CAM_HUMAN-Phosphoserine1191 def: "Protein L1CAM_HUMAN with the residue 1191 substituted with Phosphoserine" [UniProtKB:P32004] xref: UniProtKB:P32004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029795 ! L1CAM_HUMAN [Term] id: CCO:B0035080 name: L1CAM_HUMAN-Phosphoserine1194 def: "Protein L1CAM_HUMAN with the residue 1194 substituted with Phosphoserine" [UniProtKB:P32004] xref: UniProtKB:P32004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029795 ! L1CAM_HUMAN [Term] id: CCO:B0035081 name: L1CAM_HUMAN-Phosphothreonine1247 def: "Protein L1CAM_HUMAN with the residue 1247 substituted with Phosphothreonine" [UniProtKB:P32004] comment: By similarity xref: UniProtKB:P32004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029795 ! L1CAM_HUMAN [Term] id: CCO:B0035082 name: L1CAM_HUMAN-Phosphoserine1248 def: "Protein L1CAM_HUMAN with the residue 1248 substituted with Phosphoserine" [UniProtKB:P32004] xref: UniProtKB:P32004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0029795 ! L1CAM_HUMAN [Term] id: CCO:B0035085 name: LANC2_HUMAN-Phosphotyrosine198 def: "Protein LANC2_HUMAN with the residue 198 substituted with Phosphotyrosine" [UniProtKB:Q9NS86] comment: By similarity xref: UniProtKB:Q9NS86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026163 ! LANC2_HUMAN [Term] id: CCO:B0035086 name: LANC2_HUMAN-Phosphotyrosine259 def: "Protein LANC2_HUMAN with the residue 259 substituted with Phosphotyrosine" [UniProtKB:Q9NS86] comment: By similarity xref: UniProtKB:Q9NS86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026163 ! LANC2_HUMAN [Term] id: CCO:B0035087 name: LANC2_HUMAN-Phosphotyrosine295 def: "Protein LANC2_HUMAN with the residue 295 substituted with Phosphotyrosine" [UniProtKB:Q9NS86] comment: By similarity xref: UniProtKB:Q9NS86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0026163 ! LANC2_HUMAN [Term] id: CCO:B0035088 name: LASS2_HUMAN-Phosphoserine341 def: "Protein LASS2_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q96G23] xref: UniProtKB:Q96G23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:B0035089 name: LASS2_HUMAN-Phosphothreonine346 def: "Protein LASS2_HUMAN with the residue 346 substituted with Phosphothreonine" [UniProtKB:Q96G23] xref: UniProtKB:Q96G23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:B0035090 name: LASS2_HUMAN-Phosphoserine348 def: "Protein LASS2_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:Q96G23] xref: UniProtKB:Q96G23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:B0035091 name: LASS2_HUMAN-Phosphoserine349 def: "Protein LASS2_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q96G23] xref: UniProtKB:Q96G23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:B0035092 name: LASS5_HUMAN-Phosphoserine350 def: "Protein LASS5_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:Q8N5B7] xref: UniProtKB:Q8N5B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033378 ! LASS5_HUMAN [Term] id: CCO:B0035093 name: LASS5_HUMAN-Phosphoserine354 def: "Protein LASS5_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q8N5B7] xref: UniProtKB:Q8N5B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033378 ! LASS5_HUMAN [Term] id: CCO:B0035094 name: LASS5_HUMAN-Phosphoserine355 def: "Protein LASS5_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q8N5B7] xref: UniProtKB:Q8N5B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0007643 ! sphingosine N-acyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0033378 ! LASS5_HUMAN [Term] id: CCO:B0035095 name: LASS5_HUMAN-Phosphoserine356 def: "Protein LASS5_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:Q8N5B7] xref: UniProtKB:Q8N5B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033378 ! LASS5_HUMAN [Term] id: CCO:B0035098 name: LIMD1_HUMAN-Phosphoserine272 def: "Protein LIMD1_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q9UGP4] xref: UniProtKB:Q9UGP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031064 ! LIMD1_HUMAN [Term] id: CCO:B0035099 name: LIMD1_HUMAN-Phosphoserine277 def: "Protein LIMD1_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q9UGP4] xref: UniProtKB:Q9UGP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031064 ! LIMD1_HUMAN [Term] id: CCO:B0035100 name: LIPA1_HUMAN-Phosphoserine239 def: "Protein LIPA1_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0035101 name: LIPA1_HUMAN-Phosphoserine242 def: "Protein LIPA1_HUMAN with the residue 242 substituted with Phosphoserine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0035102 name: LIPA1_HUMAN-Phosphoserine776 def: "Protein LIPA1_HUMAN with the residue 776 substituted with Phosphoserine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0035118 name: LPXN_HUMAN-Phosphoserine19 def: "Protein LPXN_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:O60711] xref: UniProtKB:O60711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017845 ! LPXN_HUMAN [Term] id: CCO:B0035119 name: LPXN_HUMAN-Phosphotyrosine22 def: "Protein LPXN_HUMAN with the residue 22 substituted with Phosphotyrosine" [UniProtKB:O60711] xref: UniProtKB:O60711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017845 ! LPXN_HUMAN [Term] id: CCO:B0035120 name: LPXN_HUMAN-Phosphotyrosine62 def: "Protein LPXN_HUMAN with the residue 62 substituted with Phosphotyrosine" [UniProtKB:O60711] comment: By similarity xref: UniProtKB:O60711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0017845 ! LPXN_HUMAN [Term] id: CCO:B0035121 name: LPXN_HUMAN-Phosphotyrosine72 def: "Protein LPXN_HUMAN with the residue 72 substituted with Phosphotyrosine" [UniProtKB:O60711] comment: By similarity xref: UniProtKB:O60711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017845 ! LPXN_HUMAN [Term] id: CCO:B0035122 name: LRP1_HUMAN-Phosphothreonine4460 def: "Protein LRP1_HUMAN with the residue 4460 substituted with Phosphothreonine" [UniProtKB:Q07954] comment: Probable xref: UniProtKB:Q07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025953 ! LRP1_HUMAN [Term] id: CCO:B0035123 name: LRP1_HUMAN-Phosphotyrosine4507 def: "Protein LRP1_HUMAN with the residue 4507 substituted with Phosphotyrosine" [UniProtKB:Q07954] xref: UniProtKB:Q07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0025953 ! LRP1_HUMAN [Term] id: CCO:B0035124 name: LRP1_HUMAN-Phosphoserine4517 def: "Protein LRP1_HUMAN with the residue 4517 substituted with Phosphoserine" [UniProtKB:Q07954] comment: Probable xref: UniProtKB:Q07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025953 ! LRP1_HUMAN [Term] id: CCO:B0035125 name: LRP1_HUMAN-Phosphoserine4520 def: "Protein LRP1_HUMAN with the residue 4520 substituted with Phosphoserine" [UniProtKB:Q07954] comment: Probable xref: UniProtKB:Q07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025953 ! LRP1_HUMAN [Term] id: CCO:B0035126 name: LRP1_HUMAN-Phosphoserine4523 def: "Protein LRP1_HUMAN with the residue 4523 substituted with Phosphoserine" [UniProtKB:Q07954] comment: Probable xref: UniProtKB:Q07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025953 ! LRP1_HUMAN [Term] id: CCO:B0035133 name: LRRF1_HUMAN-Phosphoserine16 def: "Protein LRRF1_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0035134 name: LRRF1_HUMAN-Phosphothreonine123 def: "Protein LRRF1_HUMAN with the residue 123 substituted with Phosphothreonine" [UniProtKB:Q32MZ4] comment: By similarity xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0035135 name: LRRF1_HUMAN-Phosphothreonine295 def: "Protein LRRF1_HUMAN with the residue 295 substituted with Phosphothreonine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0035136 name: LRRF1_HUMAN-Phosphoserine521 def: "Protein LRRF1_HUMAN with the residue 521 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0035137 name: LRRF1_HUMAN-Phosphoserine714 def: "Protein LRRF1_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0035138 name: LRRF1_HUMAN-Phosphoserine733 def: "Protein LRRF1_HUMAN with the residue 733 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0035139 name: LRRF2_HUMAN-Phosphoserine328 def: "Protein LRRF2_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q9Y608] xref: UniProtKB:Q9Y608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032521 ! LRRF2_HUMAN [Term] id: CCO:B0035140 name: LRRF2_HUMAN-Phosphothreonine331 def: "Protein LRRF2_HUMAN with the residue 331 substituted with Phosphothreonine" [UniProtKB:Q9Y608] comment: By similarity xref: UniProtKB:Q9Y608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032521 ! LRRF2_HUMAN [Term] id: CCO:B0035141 name: LRRF2_HUMAN-Phosphoserine333 def: "Protein LRRF2_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q9Y608] comment: By similarity xref: UniProtKB:Q9Y608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004371 ! LRR domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0032521 ! LRRF2_HUMAN [Term] id: CCO:B0035153 name: M3K10_HUMAN-Phosphothreonine258 def: "Protein M3K10_HUMAN with the residue 258 substituted with Phosphothreonine" [UniProtKB:Q02779] comment: by autocatalysis; By similarity xref: UniProtKB:Q02779 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018770 ! M3K10_HUMAN [Term] id: CCO:B0035154 name: M3K10_HUMAN-Phosphoserine262 def: "Protein M3K10_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:Q02779] comment: by autocatalysis and MAP4K1; By similarity xref: UniProtKB:Q02779 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001072 ! JUN kinase kinase kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018770 ! M3K10_HUMAN [Term] id: CCO:B0035155 name: M3K10_HUMAN-Phosphoserine506 def: "Protein M3K10_HUMAN with the residue 506 substituted with Phosphoserine" [UniProtKB:Q02779] comment: By similarity xref: UniProtKB:Q02779 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018770 ! M3K10_HUMAN [Term] id: CCO:B0035156 name: M3KL4_HUMAN-Phosphothreonine299 def: "Protein M3KL4_HUMAN with the residue 299 substituted with Phosphothreonine" [UniProtKB:Q5TCX8] comment: by autocatalysis; By similarity xref: UniProtKB:Q5TCX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018759 ! M3KL4_HUMAN [Term] id: CCO:B0035157 name: M3KL4_HUMAN-Phosphoserine303 def: "Protein M3KL4_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:Q5TCX8] comment: by autocatalysis and MAP4K1; By similarity xref: UniProtKB:Q5TCX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018759 ! M3KL4_HUMAN [Term] id: CCO:B0035158 name: M3KL4_HUMAN-Phosphoserine547 def: "Protein M3KL4_HUMAN with the residue 547 substituted with Phosphoserine" [UniProtKB:Q5TCX8] comment: By similarity xref: UniProtKB:Q5TCX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018759 ! M3KL4_HUMAN [Term] id: CCO:B0035159 name: M3KL4_HUMAN-Phosphoserine732 def: "Protein M3KL4_HUMAN with the residue 732 substituted with Phosphoserine" [UniProtKB:Q5TCX8] comment: By similarity xref: UniProtKB:Q5TCX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018759 ! M3KL4_HUMAN [Term] id: CCO:B0035160 name: M3KL4_HUMAN-Phosphoserine806 def: "Protein M3KL4_HUMAN with the residue 806 substituted with Phosphoserine" [UniProtKB:Q5TCX8] comment: By similarity xref: UniProtKB:Q5TCX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018759 ! M3KL4_HUMAN [Term] id: CCO:B0035166 name: MBP_HUMAN-Phosphoserine96 def: "Protein MBP_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:P02686] xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035167 name: MBP_HUMAN-Phosphoserine141 def: "Protein MBP_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035168 name: MBP_HUMAN-Phosphoserine146 def: "Protein MBP_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035169 name: MBP_HUMAN-Citrulline159 def: "Protein MBP_HUMAN with the residue 159 substituted with Citrulline" [UniProtKB:P02686] comment: in form C8; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035170 name: MBP_HUMAN-Citrulline165 def: "Protein MBP_HUMAN with the residue 165 substituted with Citrulline" [UniProtKB:P02686] comment: in form C8; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035171 name: MBP_HUMAN-Phosphothreonine169 def: "Protein MBP_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035172 name: MBP_HUMAN-Phosphoserine174 def: "Protein MBP_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035173 name: MBP_HUMAN-Phosphotyrosine203 def: "Protein MBP_HUMAN with the residue 203 substituted with Phosphotyrosine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035174 name: MBP_HUMAN-Phosphoserine205 def: "Protein MBP_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0004216 ! structural constituent of myelin sheath relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001735 ! myelin sheath relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035175 name: MBP_HUMAN-Phosphothreonine229 def: "Protein MBP_HUMAN with the residue 229 substituted with Phosphothreonine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035176 name: MBP_HUMAN-Phosphothreonine232 def: "Protein MBP_HUMAN with the residue 232 substituted with Phosphothreonine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035177 name: MBP_HUMAN-Deamidated glutamine237 def: "Protein MBP_HUMAN with the residue 237 substituted with Deamidated glutamine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035178 name: MBP_HUMAN-Omega-N-methylarginine241 def: "Protein MBP_HUMAN with the residue 241 substituted with Omega-N-methylarginine" [UniProtKB:P02686] comment: alternate; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035179 name: MBP_HUMAN-dimethylarginine241 def: "Protein MBP_HUMAN with the residue 241 substituted with dimethylarginine" [UniProtKB:P02686] comment: alternate; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035180 name: MBP_HUMAN-Phosphoserine249 def: "Protein MBP_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035181 name: MBP_HUMAN-Citrulline256 def: "Protein MBP_HUMAN with the residue 256 substituted with Citrulline" [UniProtKB:P02686] comment: in form C8; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035182 name: MBP_HUMAN-Citrulline264 def: "Protein MBP_HUMAN with the residue 264 substituted with Citrulline" [UniProtKB:P02686] comment: in form C8; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035183 name: MBP_HUMAN-Deamidated glutamine281 def: "Protein MBP_HUMAN with the residue 281 substituted with Deamidated glutamine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035184 name: MBP_HUMAN-Citrulline293 def: "Protein MBP_HUMAN with the residue 293 substituted with Citrulline" [UniProtKB:P02686] comment: in form C8; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035185 name: MBP_HUMAN-Phosphoserine295 def: "Protein MBP_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035186 name: MBP_HUMAN-Phosphoserine299 def: "Protein MBP_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:P02686] comment: By similarity xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035187 name: MBP_HUMAN-Citrulline304 def: "Protein MBP_HUMAN with the residue 304 substituted with Citrulline" [UniProtKB:P02686] comment: in form C8; xref: UniProtKB:P02686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:B0035188 name: MDHM_HUMAN-Phosphotyrosine56 def: "Protein MDHM_HUMAN with the residue 56 substituted with Phosphotyrosine" [UniProtKB:P40926] xref: UniProtKB:P40926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003217 ! malate dehydrogenase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0004321 ! L-malate dehydrogenase activity relationship: has_function CCO:F0005879 ! protein self-association relationship: has_function CCO:F0006206 ! malate dehydrogenase (NADP+) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0030700 ! MDHM_HUMAN [Term] id: CCO:B0035189 name: MDHM_HUMAN-N6-acetyllysine157 def: "Protein MDHM_HUMAN with the residue 157 substituted with N6-acetyllysine" [UniProtKB:P40926] comment: By similarity xref: UniProtKB:P40926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030700 ! MDHM_HUMAN [Term] id: CCO:B0035190 name: MDHM_HUMAN-N6-acetyllysine239 def: "Protein MDHM_HUMAN with the residue 239 substituted with N6-acetyllysine" [UniProtKB:P40926] comment: By similarity xref: UniProtKB:P40926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030700 ! MDHM_HUMAN [Term] id: CCO:B0035191 name: MDHM_HUMAN-N6-acetyllysine314 def: "Protein MDHM_HUMAN with the residue 314 substituted with N6-acetyllysine" [UniProtKB:P40926] comment: By similarity xref: UniProtKB:P40926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030700 ! MDHM_HUMAN [Term] id: CCO:B0035193 name: MK09_HUMAN-Phosphothreonine183 def: "Protein MK09_HUMAN with the residue 183 substituted with Phosphothreonine" [UniProtKB:P45984] xref: UniProtKB:P45984 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026769 ! MK09_HUMAN [Term] id: CCO:B0035194 name: MK09_HUMAN-Phosphotyrosine185 def: "Protein MK09_HUMAN with the residue 185 substituted with Phosphotyrosine" [UniProtKB:P45984] xref: UniProtKB:P45984 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026769 ! MK09_HUMAN [Term] id: CCO:B0035195 name: MK10_HUMAN-Phosphothreonine221 def: "Protein MK10_HUMAN with the residue 221 substituted with Phosphothreonine" [UniProtKB:P53779] xref: UniProtKB:P53779 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026768 ! MK10_HUMAN [Term] id: CCO:B0035196 name: MK10_HUMAN-Phosphotyrosine223 def: "Protein MK10_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:P53779] xref: UniProtKB:P53779 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001071 ! JUN kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0026768 ! MK10_HUMAN [Term] id: CCO:B0035197 name: MK14_HUMAN-Phosphothreonine180 def: "Protein MK14_HUMAN with the residue 180 substituted with Phosphothreonine" [UniProtKB:Q16539] xref: UniProtKB:Q16539 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021108 ! MK14_HUMAN [Term] id: CCO:B0035198 name: MK14_HUMAN-Phosphotyrosine182 def: "Protein MK14_HUMAN with the residue 182 substituted with Phosphotyrosine" [UniProtKB:Q16539] xref: UniProtKB:Q16539 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001844 ! MP kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0021108 ! MK14_HUMAN [Term] id: CCO:B0035199 name: MK14_HUMAN-Phosphothreonine263 def: "Protein MK14_HUMAN with the residue 263 substituted with Phosphothreonine" [UniProtKB:Q16539] xref: UniProtKB:Q16539 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021108 ! MK14_HUMAN [Term] id: CCO:B0035200 name: MOES_HUMAN-N6-acetyllysine64 def: "Protein MOES_HUMAN with the residue 64 substituted with N6-acetyllysine" [UniProtKB:P26038] xref: UniProtKB:P26038 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018220 ! MOES_HUMAN [Term] id: CCO:B0035201 name: MOES_HUMAN-Phosphotyrosine116 def: "Protein MOES_HUMAN with the residue 116 substituted with Phosphotyrosine" [UniProtKB:P26038] comment: By similarity xref: UniProtKB:P26038 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018220 ! MOES_HUMAN [Term] id: CCO:B0035202 name: MOES_HUMAN-Phosphothreonine558 def: "Protein MOES_HUMAN with the residue 558 substituted with Phosphothreonine" [UniProtKB:P26038] comment: By similarity xref: UniProtKB:P26038 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0008023 ! cell adhesion molecule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001896 ! apical part of cell relationship: transformation_of CCO:B0018220 ! MOES_HUMAN [Term] id: CCO:B0035203 name: MOES_HUMAN-Phosphoserine576 def: "Protein MOES_HUMAN with the residue 576 substituted with Phosphoserine" [UniProtKB:P26038] comment: By similarity xref: UniProtKB:P26038 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018220 ! MOES_HUMAN [Term] id: CCO:B0035205 name: MOL1B_HUMAN-N-acetylserine2 def: "Protein MOL1B_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9H8S9] xref: UniProtKB:Q9H8S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024568 ! MOL1B_HUMAN [Term] id: CCO:B0035206 name: MOL1B_HUMAN-Phosphoserine23 def: "Protein MOL1B_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q9H8S9] xref: UniProtKB:Q9H8S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024568 ! MOL1B_HUMAN [Term] id: CCO:B0035207 name: MOL1B_HUMAN-Phosphothreonine35 def: "Protein MOL1B_HUMAN with the residue 35 substituted with Phosphothreonine" [UniProtKB:Q9H8S9] xref: UniProtKB:Q9H8S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024568 ! MOL1B_HUMAN [Term] id: CCO:B0035208 name: MOL1B_HUMAN-Phosphoserine38 def: "Protein MOL1B_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:Q9H8S9] comment: By similarity xref: UniProtKB:Q9H8S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024568 ! MOL1B_HUMAN [Term] id: CCO:B0035209 name: MP2K2_HUMAN-Phosphoserine23 def: "Protein MP2K2_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:P36507] xref: UniProtKB:P36507 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:B0035210 name: MP2K2_HUMAN-Phosphoserine222 def: "Protein MP2K2_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:P36507] comment: by RAF; xref: UniProtKB:P36507 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:B0035211 name: MP2K2_HUMAN-Phosphoserine226 def: "Protein MP2K2_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:P36507] xref: UniProtKB:P36507 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:B0035212 name: MP2K2_HUMAN-Phosphothreonine394 def: "Protein MP2K2_HUMAN with the residue 394 substituted with Phosphothreonine" [UniProtKB:P36507] xref: UniProtKB:P36507 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:B0035213 name: MP2K2_HUMAN-Phosphothreonine396 def: "Protein MP2K2_HUMAN with the residue 396 substituted with Phosphothreonine" [UniProtKB:P36507] xref: UniProtKB:P36507 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:B0035214 name: MST4_HUMAN-Phosphothreonine178 def: "Protein MST4_HUMAN with the residue 178 substituted with Phosphothreonine" [UniProtKB:Q9P289] comment: by autocatalysis; By similarity xref: UniProtKB:Q9P289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:B0035223 name: MYH1_HUMAN-N6,N6,N6-trimethyllysine130 def: "Protein MYH1_HUMAN with the residue 130 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P12882] comment: Potential xref: UniProtKB:P12882 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027842 ! MYH1_HUMAN [Term] id: CCO:B0035224 name: MYH1_HUMAN-Phosphoserine1928 def: "Protein MYH1_HUMAN with the residue 1928 substituted with Phosphoserine" [UniProtKB:P12882] comment: By similarity xref: UniProtKB:P12882 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027842 ! MYH1_HUMAN [Term] id: CCO:B0035225 name: MYH1_HUMAN-Phosphothreonine1933 def: "Protein MYH1_HUMAN with the residue 1933 substituted with Phosphothreonine" [UniProtKB:P12882] comment: By similarity xref: UniProtKB:P12882 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000426 ! striated muscle thick filament relationship: located_in CCO:C0000788 ! myosin complex relationship: transformation_of CCO:B0027842 ! MYH1_HUMAN [Term] id: CCO:B0035233 name: MYH9_HUMAN-N-acetylalanine2 def: "Protein MYH9_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P35579] xref: UniProtKB:P35579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:B0035234 name: MYH9_HUMAN-Phosphothreonine181 def: "Protein MYH9_HUMAN with the residue 181 substituted with Phosphothreonine" [UniProtKB:P35579] comment: By similarity xref: UniProtKB:P35579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000026 ! microfilament motor activity relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004599 ! actin-dependent ATPase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005861 ! protein anchor relationship: has_function CCO:F0005867 ! ADP binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000186 ! immunological synapse relationship: located_in CCO:C0000189 ! uropod relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000394 ! contractile ring relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0001172 ! leading edge relationship: located_in CCO:C0001403 ! cleavage furrow relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:B0035235 name: MYH9_HUMAN-Phosphothreonine638 def: "Protein MYH9_HUMAN with the residue 638 substituted with Phosphothreonine" [UniProtKB:P35579] comment: By similarity xref: UniProtKB:P35579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:B0035236 name: MYH9_HUMAN-Phosphotyrosine754 def: "Protein MYH9_HUMAN with the residue 754 substituted with Phosphotyrosine" [UniProtKB:P35579] xref: UniProtKB:P35579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:B0035237 name: MYH9_HUMAN-Phosphoserine1943 def: "Protein MYH9_HUMAN with the residue 1943 substituted with Phosphoserine" [UniProtKB:P35579] xref: UniProtKB:P35579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:B0035239 name: MYST3_HUMAN-Phosphoserine473 def: "Protein MYST3_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:Q92794] xref: UniProtKB:Q92794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:B0035240 name: MYST3_HUMAN-N6-acetyllysine815 def: "Protein MYST3_HUMAN with the residue 815 substituted with N6-acetyllysine" [UniProtKB:Q92794] xref: UniProtKB:Q92794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:B0035241 name: MYST3_HUMAN-Phosphothreonine909 def: "Protein MYST3_HUMAN with the residue 909 substituted with Phosphothreonine" [UniProtKB:Q92794] xref: UniProtKB:Q92794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:B0035242 name: MYST3_HUMAN-Phosphoserine1113 def: "Protein MYST3_HUMAN with the residue 1113 substituted with Phosphoserine" [UniProtKB:Q92794] xref: UniProtKB:Q92794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:B0035243 name: MYST4_HUMAN-Phosphoserine1027 def: "Protein MYST4_HUMAN with the residue 1027 substituted with Phosphoserine" [UniProtKB:Q8WYB5] xref: UniProtKB:Q8WYB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017931 ! MYST4_HUMAN [Term] id: CCO:B0035244 name: MYST4_HUMAN-Phosphothreonine1915 def: "Protein MYST4_HUMAN with the residue 1915 substituted with Phosphothreonine" [UniProtKB:Q8WYB5] xref: UniProtKB:Q8WYB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017931 ! MYST4_HUMAN [Term] id: CCO:B0035249 name: NED4L_HUMAN-Phosphothreonine302 def: "Protein NED4L_HUMAN with the residue 302 substituted with Phosphothreonine" [UniProtKB:Q96PU5] comment: By similarity xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035250 name: NED4L_HUMAN-Phosphoserine342 def: "Protein NED4L_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035251 name: NED4L_HUMAN-Phosphothreonine367 def: "Protein NED4L_HUMAN with the residue 367 substituted with Phosphothreonine" [UniProtKB:Q96PU5] comment: by SGK; Probable xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035252 name: NED4L_HUMAN-Phosphoserine446 def: "Protein NED4L_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035253 name: NED4L_HUMAN-Phosphoserine448 def: "Protein NED4L_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:Q96PU5] comment: by PKA and SGK; xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035254 name: NED4L_HUMAN-Phosphoserine479 def: "Protein NED4L_HUMAN with the residue 479 substituted with Phosphoserine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035255 name: NED4L_HUMAN-Phosphoserine483 def: "Protein NED4L_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035256 name: NED4L_HUMAN-Phosphoserine487 def: "Protein NED4L_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0035259 name: NEK3_HUMAN-Phosphothreonine161 def: "Protein NEK3_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:P51956] comment: by autocatalysis; By similarity xref: UniProtKB:P51956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028319 ! NEK3_HUMAN [Term] id: CCO:B0035260 name: NEK3_HUMAN-Phosphoserine394 def: "Protein NEK3_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:P51956] xref: UniProtKB:P51956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028319 ! NEK3_HUMAN [Term] id: CCO:B0035261 name: NEK3_HUMAN-Phosphothreonine402 def: "Protein NEK3_HUMAN with the residue 402 substituted with Phosphothreonine" [UniProtKB:P51956] xref: UniProtKB:P51956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028319 ! NEK3_HUMAN [Term] id: CCO:B0035262 name: NEK3_HUMAN-Phosphothreonine479 def: "Protein NEK3_HUMAN with the residue 479 substituted with Phosphothreonine" [UniProtKB:P51956] comment: By similarity xref: UniProtKB:P51956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028319 ! NEK3_HUMAN [Term] id: CCO:B0035266 name: NGAP_HUMAN-Phosphoserine11 def: "Protein NGAP_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:Q9UJF2] xref: UniProtKB:Q9UJF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019350 ! NGAP_HUMAN [Term] id: CCO:B0035267 name: NMDE1_HUMAN-Phosphothreonine888 def: "Protein NMDE1_HUMAN with the residue 888 substituted with Phosphothreonine" [UniProtKB:Q12879] comment: By similarity xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035268 name: NMDE1_HUMAN-Phosphoserine912 def: "Protein NMDE1_HUMAN with the residue 912 substituted with Phosphoserine" [UniProtKB:Q12879] xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035269 name: NMDE1_HUMAN-Phosphoserine917 def: "Protein NMDE1_HUMAN with the residue 917 substituted with Phosphoserine" [UniProtKB:Q12879] xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001313 ! N-methyl-D-aspartate selective glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001524 ! cation channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003210 ! glutamate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000845 ! N-methyl-D-aspartate selective glutamate receptor complex relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035270 name: NMDE1_HUMAN-Phosphoserine929 def: "Protein NMDE1_HUMAN with the residue 929 substituted with Phosphoserine" [UniProtKB:Q12879] comment: By similarity xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035271 name: NMDE1_HUMAN-Phosphotyrosine943 def: "Protein NMDE1_HUMAN with the residue 943 substituted with Phosphotyrosine" [UniProtKB:Q12879] comment: By similarity xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035272 name: NMDE1_HUMAN-Phosphoserine1025 def: "Protein NMDE1_HUMAN with the residue 1025 substituted with Phosphoserine" [UniProtKB:Q12879] comment: By similarity xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035273 name: NMDE1_HUMAN-Phosphoserine1337 def: "Protein NMDE1_HUMAN with the residue 1337 substituted with Phosphoserine" [UniProtKB:Q12879] xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035274 name: NMDE1_HUMAN-Phosphoserine1459 def: "Protein NMDE1_HUMAN with the residue 1459 substituted with Phosphoserine" [UniProtKB:Q12879] comment: By similarity xref: UniProtKB:Q12879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033427 ! NMDE1_HUMAN [Term] id: CCO:B0035275 name: NMDE2_HUMAN-Phosphoserine917 def: "Protein NMDE2_HUMAN with the residue 917 substituted with Phosphoserine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035276 name: NMDE2_HUMAN-Phosphoserine930 def: "Protein NMDE2_HUMAN with the residue 930 substituted with Phosphoserine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035277 name: NMDE2_HUMAN-Phosphotyrosine932 def: "Protein NMDE2_HUMAN with the residue 932 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035278 name: NMDE2_HUMAN-Phosphotyrosine949 def: "Protein NMDE2_HUMAN with the residue 949 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035279 name: NMDE2_HUMAN-Phosphotyrosine962 def: "Protein NMDE2_HUMAN with the residue 962 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001313 ! N-methyl-D-aspartate selective glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003209 ! glycine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000845 ! N-methyl-D-aspartate selective glutamate receptor complex relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035280 name: NMDE2_HUMAN-Phosphotyrosine1039 def: "Protein NMDE2_HUMAN with the residue 1039 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035281 name: NMDE2_HUMAN-Phosphotyrosine1049 def: "Protein NMDE2_HUMAN with the residue 1049 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035282 name: NMDE2_HUMAN-Phosphoserine1061 def: "Protein NMDE2_HUMAN with the residue 1061 substituted with Phosphoserine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035283 name: NMDE2_HUMAN-Phosphothreonine1065 def: "Protein NMDE2_HUMAN with the residue 1065 substituted with Phosphothreonine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035284 name: NMDE2_HUMAN-Phosphotyrosine1070 def: "Protein NMDE2_HUMAN with the residue 1070 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035285 name: NMDE2_HUMAN-Phosphotyrosine1109 def: "Protein NMDE2_HUMAN with the residue 1109 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035286 name: NMDE2_HUMAN-Phosphotyrosine1155 def: "Protein NMDE2_HUMAN with the residue 1155 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035287 name: NMDE2_HUMAN-Phosphoserine1166 def: "Protein NMDE2_HUMAN with the residue 1166 substituted with Phosphoserine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035288 name: NMDE2_HUMAN-Phosphotyrosine1252 def: "Protein NMDE2_HUMAN with the residue 1252 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035289 name: NMDE2_HUMAN-Phosphoserine1303 def: "Protein NMDE2_HUMAN with the residue 1303 substituted with Phosphoserine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035290 name: NMDE2_HUMAN-Phosphotyrosine1304 def: "Protein NMDE2_HUMAN with the residue 1304 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035291 name: NMDE2_HUMAN-Phosphotyrosine1474 def: "Protein NMDE2_HUMAN with the residue 1474 substituted with Phosphotyrosine" [UniProtKB:Q13224] comment: By similarity xref: UniProtKB:Q13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:B0035292 name: NMDE4_HUMAN-Phosphoserine1326 def: "Protein NMDE4_HUMAN with the residue 1326 substituted with Phosphoserine" [UniProtKB:O15399] comment: By similarity xref: UniProtKB:O15399 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0033433 ! NMDE4_HUMAN [Term] id: CCO:B0035305 name: NR2F6_HUMAN-Phosphoserine34 def: "Protein NR2F6_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P10588] xref: UniProtKB:P10588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024893 ! NR2F6_HUMAN [Term] id: CCO:B0035306 name: NR2F6_HUMAN-Phosphoserine40 def: "Protein NR2F6_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:P10588] comment: By similarity xref: UniProtKB:P10588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024893 ! NR2F6_HUMAN [Term] id: CCO:B0035307 name: NRCAM_HUMAN-Phosphoserine427 def: "Protein NRCAM_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q92823] comment: By similarity xref: UniProtKB:Q92823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004447 ! ankyrin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: transformation_of CCO:B0015672 ! NRCAM_HUMAN [Term] id: CCO:B0035308 name: NRCAM_HUMAN-Phosphoserine1295 def: "Protein NRCAM_HUMAN with the residue 1295 substituted with Phosphoserine" [UniProtKB:Q92823] comment: By similarity xref: UniProtKB:Q92823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015672 ! NRCAM_HUMAN [Term] id: CCO:B0035311 name: NTKL_HUMAN-Phosphoserine754 def: "Protein NTKL_HUMAN with the residue 754 substituted with Phosphoserine" [UniProtKB:Q96KG9] xref: UniProtKB:Q96KG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0031563 ! NTKL_HUMAN [Term] id: CCO:B0035322 name: PAIRB_HUMAN-Phosphoserine25 def: "Protein PAIRB_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035323 name: PAIRB_HUMAN-Phosphothreonine61 def: "Protein PAIRB_HUMAN with the residue 61 substituted with Phosphothreonine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035324 name: PAIRB_HUMAN-Phosphoserine85 def: "Protein PAIRB_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035325 name: PAIRB_HUMAN-Phosphoserine197 def: "Protein PAIRB_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035326 name: PAIRB_HUMAN-Phosphoserine203 def: "Protein PAIRB_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035327 name: PAIRB_HUMAN-Phosphoserine221 def: "Protein PAIRB_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035328 name: PAIRB_HUMAN-Phosphothreonine232 def: "Protein PAIRB_HUMAN with the residue 232 substituted with Phosphothreonine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035329 name: PAIRB_HUMAN-Phosphoserine234 def: "Protein PAIRB_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035330 name: PAIRB_HUMAN-Phosphotyrosine244 def: "Protein PAIRB_HUMAN with the residue 244 substituted with Phosphotyrosine" [UniProtKB:Q8NC51] comment: By similarity xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035331 name: PAIRB_HUMAN-Phosphoserine252 def: "Protein PAIRB_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035332 name: PAIRB_HUMAN-Phosphoserine328 def: "Protein PAIRB_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035333 name: PAIRB_HUMAN-Phosphoserine330 def: "Protein PAIRB_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035334 name: PAIRB_HUMAN-Phosphoserine391 def: "Protein PAIRB_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q8NC51] comment: By similarity xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0035335 name: PAK2_HUMAN-Phosphoserine2 def: "Protein PAK2_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q13177] xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0035336 name: PAK2_HUMAN-Phosphotyrosine139 def: "Protein PAK2_HUMAN with the residue 139 substituted with Phosphotyrosine" [UniProtKB:Q13177] comment: By similarity xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0035337 name: PAK2_HUMAN-Phosphoserine141 def: "Protein PAK2_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q13177] xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0035338 name: PAK2_HUMAN-Phosphothreonine143 def: "Protein PAK2_HUMAN with the residue 143 substituted with Phosphothreonine" [UniProtKB:Q13177] xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0035339 name: PAK2_HUMAN-Phosphothreonine402 def: "Protein PAK2_HUMAN with the residue 402 substituted with Phosphothreonine" [UniProtKB:Q13177] comment: by autocatalysis; Probable xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0035343 name: PCBP1_HUMAN-Phosphoserine173 def: "Protein PCBP1_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q15365] xref: UniProtKB:Q15365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:B0035344 name: PCBP1_HUMAN-Phosphoserine190 def: "Protein PCBP1_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q15365] xref: UniProtKB:Q15365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:B0035345 name: PCBP1_HUMAN-Phosphoserine246 def: "Protein PCBP1_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q15365] xref: UniProtKB:Q15365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:B0035346 name: PCBP1_HUMAN-Phosphoserine262 def: "Protein PCBP1_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:Q15365] xref: UniProtKB:Q15365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:B0035347 name: PCBP1_HUMAN-Phosphoserine263 def: "Protein PCBP1_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q15365] xref: UniProtKB:Q15365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:B0035348 name: PCBP1_HUMAN-Phosphoserine264 def: "Protein PCBP1_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q15365] xref: UniProtKB:Q15365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:B0035355 name: PDE7A_HUMAN-Phosphoserine84 def: "Protein PDE7A_HUMAN with the residue 84 substituted with Phosphoserine" [UniProtKB:Q13946] comment: Potential xref: UniProtKB:Q13946 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000587 ! 3',5'-cyclic-AMP phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000046 ! cell fraction relationship: transformation_of CCO:B0027478 ! PDE7A_HUMAN [Term] id: CCO:B0035356 name: PDK4_HUMAN-Phosphohistidine127 def: "Protein PDK4_HUMAN with the residue 127 substituted with Phosphohistidine" [UniProtKB:Q16654] comment: by autocatalysis; By similarity xref: UniProtKB:Q16654 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001044 ! protein histidine kinase activity relationship: has_function CCO:F0001105 ! pyruvate dehydrogenase (acetyl-transferring) kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0016805 ! PDK4_HUMAN [Term] id: CCO:B0035357 name: PDXK_HUMAN-N-acetylmethionine1 def: "Protein PDXK_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:O00764] comment: By similarity xref: UniProtKB:O00764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001939 ! pyridoxal kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_function CCO:F0004657 ! lithium ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0021138 ! PDXK_HUMAN [Term] id: CCO:B0035358 name: PECA1_HUMAN-Phosphotyrosine713 def: "Protein PECA1_HUMAN with the residue 713 substituted with Phosphotyrosine" [UniProtKB:P16284] xref: UniProtKB:P16284 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001129 ! platelet alpha granule membrane relationship: transformation_of CCO:B0026626 ! PECA1_HUMAN [Term] id: CCO:B0035366 name: PGFRA_HUMAN-Phosphotyrosine849 def: "Protein PGFRA_HUMAN with the residue 849 substituted with Phosphotyrosine" [UniProtKB:P16234] comment: by autocatalysis; By similarity xref: UniProtKB:P16234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020505 ! PGFRA_HUMAN [Term] id: CCO:B0035367 name: PGFRB_HUMAN-Phosphotyrosine751 def: "Protein PGFRB_HUMAN with the residue 751 substituted with Phosphotyrosine" [UniProtKB:P09619] comment: by autocatalysis; xref: UniProtKB:P09619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020508 ! PGFRB_HUMAN [Term] id: CCO:B0035368 name: PGFRB_HUMAN-Phosphotyrosine857 def: "Protein PGFRB_HUMAN with the residue 857 substituted with Phosphotyrosine" [UniProtKB:P09619] comment: by autocatalysis; xref: UniProtKB:P09619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001330 ! platelet activating factor receptor activity relationship: has_function CCO:F0001349 ! platelet-derived growth factor receptor activity relationship: has_function CCO:F0001351 ! platelet-derived growth factor beta-receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0007337 ! platelet-derived growth factor binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0020508 ! PGFRB_HUMAN [Term] id: CCO:B0035369 name: PKHA6_HUMAN-Phosphoserine472 def: "Protein PKHA6_HUMAN with the residue 472 substituted with Phosphoserine" [UniProtKB:Q9Y2H5] xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0035370 name: PKHA6_HUMAN-Phosphoserine476 def: "Protein PKHA6_HUMAN with the residue 476 substituted with Phosphoserine" [UniProtKB:Q9Y2H5] xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0035371 name: PKHA6_HUMAN-Phosphotyrosine492 def: "Protein PKHA6_HUMAN with the residue 492 substituted with Phosphotyrosine" [UniProtKB:Q9Y2H5] xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0035372 name: PKHA6_HUMAN-Phosphothreonine744 def: "Protein PKHA6_HUMAN with the residue 744 substituted with Phosphothreonine" [UniProtKB:Q9Y2H5] comment: By similarity xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0035373 name: PKHA6_HUMAN-Phosphoserine777 def: "Protein PKHA6_HUMAN with the residue 777 substituted with Phosphoserine" [UniProtKB:Q9Y2H5] comment: By similarity xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0035374 name: PKHA6_HUMAN-Phosphoserine848 def: "Protein PKHA6_HUMAN with the residue 848 substituted with Phosphoserine" [UniProtKB:Q9Y2H5] xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0035375 name: PKHA6_HUMAN-Phosphoserine854 def: "Protein PKHA6_HUMAN with the residue 854 substituted with Phosphoserine" [UniProtKB:Q9Y2H5] xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0035380 name: PKN2_HUMAN-Phosphoserine289 def: "Protein PKN2_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035381 name: PKN2_HUMAN-Phosphoserine302 def: "Protein PKN2_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035382 name: PKN2_HUMAN-Phosphoserine306 def: "Protein PKN2_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035383 name: PKN2_HUMAN-Phosphoserine360 def: "Protein PKN2_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035384 name: PKN2_HUMAN-Phosphoserine531 def: "Protein PKN2_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035385 name: PKN2_HUMAN-Phosphoserine535 def: "Protein PKN2_HUMAN with the residue 535 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035386 name: PKN2_HUMAN-Phosphoserine559 def: "Protein PKN2_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035387 name: PKN2_HUMAN-Phosphoserine561 def: "Protein PKN2_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035388 name: PKN2_HUMAN-Phosphoserine582 def: "Protein PKN2_HUMAN with the residue 582 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035389 name: PKN2_HUMAN-Phosphoserine583 def: "Protein PKN2_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035390 name: PKN2_HUMAN-Phosphothreonine816 def: "Protein PKN2_HUMAN with the residue 816 substituted with Phosphothreonine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035391 name: PKN2_HUMAN-Phosphothreonine958 def: "Protein PKN2_HUMAN with the residue 958 substituted with Phosphothreonine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0035392 name: PKN3_HUMAN-Phosphoserine544 def: "Protein PKN3_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:Q6P5Z2] xref: UniProtKB:Q6P5Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0021018 ! PKN3_HUMAN [Term] id: CCO:B0035393 name: PKN3_HUMAN-Phosphothreonine550 def: "Protein PKN3_HUMAN with the residue 550 substituted with Phosphothreonine" [UniProtKB:Q6P5Z2] xref: UniProtKB:Q6P5Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021018 ! PKN3_HUMAN [Term] id: CCO:B0035394 name: PKN3_HUMAN-Phosphothreonine718 def: "Protein PKN3_HUMAN with the residue 718 substituted with Phosphothreonine" [UniProtKB:Q6P5Z2] xref: UniProtKB:Q6P5Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021018 ! PKN3_HUMAN [Term] id: CCO:B0035395 name: PKN3_HUMAN-Phosphothreonine860 def: "Protein PKN3_HUMAN with the residue 860 substituted with Phosphothreonine" [UniProtKB:Q6P5Z2] comment: Probable xref: UniProtKB:Q6P5Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021018 ! PKN3_HUMAN [Term] id: CCO:B0035396 name: PLD1_HUMAN-Phosphoserine629 def: "Protein PLD1_HUMAN with the residue 629 substituted with Phosphoserine" [UniProtKB:Q13393] xref: UniProtKB:Q13393 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001004 ! phospholipase D activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: transformation_of CCO:B0020556 ! PLD1_HUMAN [Term] id: CCO:B0035397 name: PLSL_HUMAN-N-acetylalanine2 def: "Protein PLSL_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P13796] xref: UniProtKB:P13796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:B0035398 name: PLSL_HUMAN-Phosphoserine5 def: "Protein PLSL_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:P13796] comment: By similarity xref: UniProtKB:P13796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:B0035399 name: PLSL_HUMAN-Phosphoserine7 def: "Protein PLSL_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:P13796] comment: By similarity xref: UniProtKB:P13796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:B0035400 name: PLSL_HUMAN-Phosphotyrosine124 def: "Protein PLSL_HUMAN with the residue 124 substituted with Phosphotyrosine" [UniProtKB:P13796] xref: UniProtKB:P13796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:B0035401 name: PLST_HUMAN-Phosphothreonine114 def: "Protein PLST_HUMAN with the residue 114 substituted with Phosphothreonine" [UniProtKB:P13797] xref: UniProtKB:P13797 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019585 ! PLST_HUMAN [Term] id: CCO:B0035405 name: POLH_HUMAN-Phosphoserine379 def: "Protein POLH_HUMAN with the residue 379 substituted with Phosphoserine" [UniProtKB:Q9Y253] xref: UniProtKB:Q9Y253 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014914 ! POLH_HUMAN [Term] id: CCO:B0035406 name: POLH_HUMAN-Phosphoserine380 def: "Protein POLH_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q9Y253] xref: UniProtKB:Q9Y253 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0014914 ! POLH_HUMAN [Term] id: CCO:B0035416 name: PPAC_HUMAN-N-acetylalanine2 def: "Protein PPAC_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P24666] xref: UniProtKB:P24666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022236 ! PPAC_HUMAN [Term] id: CCO:B0035417 name: PPAC_HUMAN-Phosphotyrosine132 def: "Protein PPAC_HUMAN with the residue 132 substituted with Phosphotyrosine" [UniProtKB:P24666] xref: UniProtKB:P24666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022236 ! PPAC_HUMAN [Term] id: CCO:B0035418 name: PPAC_HUMAN-Phosphotyrosine133 def: "Protein PPAC_HUMAN with the residue 133 substituted with Phosphotyrosine" [UniProtKB:P24666] xref: UniProtKB:P24666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000478 ! acid phosphatase activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001091 ! non-membrane spanning protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0022236 ! PPAC_HUMAN [Term] id: CCO:B0035440 name: PRP4B_HUMAN-Phosphoserine20 def: "Protein PRP4B_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035441 name: PRP4B_HUMAN-Phosphoserine23 def: "Protein PRP4B_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035442 name: PRP4B_HUMAN-Phosphoserine32 def: "Protein PRP4B_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035443 name: PRP4B_HUMAN-Phosphoserine36 def: "Protein PRP4B_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035444 name: PRP4B_HUMAN-Phosphoserine87 def: "Protein PRP4B_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035445 name: PRP4B_HUMAN-Phosphoserine93 def: "Protein PRP4B_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035446 name: PRP4B_HUMAN-Phosphoserine239 def: "Protein PRP4B_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035447 name: PRP4B_HUMAN-Phosphoserine241 def: "Protein PRP4B_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035448 name: PRP4B_HUMAN-Phosphoserine257 def: "Protein PRP4B_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035449 name: PRP4B_HUMAN-Phosphoserine277 def: "Protein PRP4B_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035450 name: PRP4B_HUMAN-Phosphoserine292 def: "Protein PRP4B_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035451 name: PRP4B_HUMAN-Phosphoserine294 def: "Protein PRP4B_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035452 name: PRP4B_HUMAN-Phosphoserine328 def: "Protein PRP4B_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035453 name: PRP4B_HUMAN-Phosphoserine354 def: "Protein PRP4B_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035454 name: PRP4B_HUMAN-Phosphoserine356 def: "Protein PRP4B_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035455 name: PRP4B_HUMAN-Phosphoserine366 def: "Protein PRP4B_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035456 name: PRP4B_HUMAN-Phosphoserine368 def: "Protein PRP4B_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035457 name: PRP4B_HUMAN-Phosphoserine381 def: "Protein PRP4B_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035458 name: PRP4B_HUMAN-Phosphothreonine385 def: "Protein PRP4B_HUMAN with the residue 385 substituted with Phosphothreonine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035459 name: PRP4B_HUMAN-Phosphoserine387 def: "Protein PRP4B_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035460 name: PRP4B_HUMAN-Phosphoserine410 def: "Protein PRP4B_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035461 name: PRP4B_HUMAN-Phosphoserine411 def: "Protein PRP4B_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035462 name: PRP4B_HUMAN-Phosphoserine427 def: "Protein PRP4B_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035463 name: PRP4B_HUMAN-Phosphoserine431 def: "Protein PRP4B_HUMAN with the residue 431 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035464 name: PRP4B_HUMAN-Phosphoserine437 def: "Protein PRP4B_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035465 name: PRP4B_HUMAN-Phosphoserine569 def: "Protein PRP4B_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035466 name: PRP4B_HUMAN-Phosphothreonine576 def: "Protein PRP4B_HUMAN with the residue 576 substituted with Phosphothreonine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035467 name: PRP4B_HUMAN-Phosphoserine578 def: "Protein PRP4B_HUMAN with the residue 578 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035468 name: PRP4B_HUMAN-Phosphoserine580 def: "Protein PRP4B_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035469 name: PRP4B_HUMAN-Phosphotyrosine849 def: "Protein PRP4B_HUMAN with the residue 849 substituted with Phosphotyrosine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035470 name: PRP4B_HUMAN-Phosphoserine852 def: "Protein PRP4B_HUMAN with the residue 852 substituted with Phosphoserine" [UniProtKB:Q13523] comment: By similarity xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0035471 name: PRP8_HUMAN-Phosphothreonine1318 def: "Protein PRP8_HUMAN with the residue 1318 substituted with Phosphothreonine" [UniProtKB:Q6P2Q9] comment: By similarity xref: UniProtKB:Q6P2Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000284 ! snRNP U5 relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0020752 ! PRP8_HUMAN [Term] id: CCO:B0035472 name: PRP8_HUMAN-Phosphothreonine2042 def: "Protein PRP8_HUMAN with the residue 2042 substituted with Phosphothreonine" [UniProtKB:Q6P2Q9] xref: UniProtKB:Q6P2Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020752 ! PRP8_HUMAN [Term] id: CCO:B0035473 name: PRP8_HUMAN-Phosphothreonine2064 def: "Protein PRP8_HUMAN with the residue 2064 substituted with Phosphothreonine" [UniProtKB:Q6P2Q9] xref: UniProtKB:Q6P2Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020752 ! PRP8_HUMAN [Term] id: CCO:B0035474 name: PSA5_HUMAN-N-acetylmethionine1 def: "Protein PSA5_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P28066] xref: UniProtKB:P28066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022204 ! PSA5_HUMAN [Term] id: CCO:B0035475 name: PSA5_HUMAN-Phosphoserine16 def: "Protein PSA5_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:P28066] xref: UniProtKB:P28066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022204 ! PSA5_HUMAN [Term] id: CCO:B0035476 name: PSA5_HUMAN-Phosphoserine56 def: "Protein PSA5_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:P28066] xref: UniProtKB:P28066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022204 ! PSA5_HUMAN [Term] id: CCO:B0035477 name: PSA7_HUMAN-N-acetylserine2 def: "Protein PSA7_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:O14818] xref: UniProtKB:O14818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: transformation_of CCO:B0030768 ! PSA7_HUMAN [Term] id: CCO:B0035478 name: PSB1_HUMAN-Phosphotyrosine150 def: "Protein PSB1_HUMAN with the residue 150 substituted with Phosphotyrosine" [UniProtKB:P20618] comment: By similarity xref: UniProtKB:P20618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: transformation_of CCO:B0030961 ! PSB1_HUMAN [Term] id: CCO:B0035479 name: PSB2_HUMAN-N-acetylmethionine1 def: "Protein PSB2_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P49721] xref: UniProtKB:P49721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: transformation_of CCO:B0030800 ! PSB2_HUMAN [Term] id: CCO:B0035480 name: PSB3_HUMAN-N-acetylserine2 def: "Protein PSB3_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P49720] xref: UniProtKB:P49720 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030929 ! PSB3_HUMAN [Term] id: CCO:B0035481 name: PSB7_HUMAN-Phosphotyrosine154 def: "Protein PSB7_HUMAN with the residue 154 substituted with Phosphotyrosine" [UniProtKB:Q99436] xref: UniProtKB:Q99436 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:B0035482 name: PSD13_HUMAN-Phosphoserine106 def: "Protein PSD13_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q9UNM6] xref: UniProtKB:Q9UNM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030887 ! PSD13_HUMAN [Term] id: CCO:B0035483 name: PSD7_HUMAN-Phosphothreonine186 def: "Protein PSD7_HUMAN with the residue 186 substituted with Phosphothreonine" [UniProtKB:P51665] xref: UniProtKB:P51665 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002079 ! proteasome regulatory particle relationship: transformation_of CCO:B0031003 ! PSD7_HUMAN [Term] id: CCO:B0035484 name: PSDE_HUMAN-Phosphotyrosine32 def: "Protein PSDE_HUMAN with the residue 32 substituted with Phosphotyrosine" [UniProtKB:O00487] xref: UniProtKB:O00487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023606 ! PSDE_HUMAN [Term] id: CCO:B0035485 name: PSDE_HUMAN-Phosphoserine224 def: "Protein PSDE_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:O00487] xref: UniProtKB:O00487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023606 ! PSDE_HUMAN [Term] id: CCO:B0035486 name: PSF2_HUMAN-Phosphothreonine180 def: "Protein PSF2_HUMAN with the residue 180 substituted with Phosphothreonine" [UniProtKB:Q9Y248] xref: UniProtKB:Q9Y248 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0017505 ! PSF2_HUMAN [Term] id: CCO:B0035487 name: PSF2_HUMAN-Phosphoserine182 def: "Protein PSF2_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q9Y248] xref: UniProtKB:Q9Y248 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017505 ! PSF2_HUMAN [Term] id: CCO:B0035491 name: PURB_HUMAN-N-acetylalanine2 def: "Protein PURB_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q96QR8] comment: By similarity xref: UniProtKB:Q96QR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:B0035492 name: PURB_HUMAN-Phosphoserine6 def: "Protein PURB_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q96QR8] xref: UniProtKB:Q96QR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:B0035493 name: PURB_HUMAN-Phosphoserine8 def: "Protein PURB_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q96QR8] xref: UniProtKB:Q96QR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:B0035494 name: PURB_HUMAN-Phosphothreonine31 def: "Protein PURB_HUMAN with the residue 31 substituted with Phosphothreonine" [UniProtKB:Q96QR8] comment: By similarity xref: UniProtKB:Q96QR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:B0035495 name: PURB_HUMAN-Phosphoserine298 def: "Protein PURB_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:Q96QR8] xref: UniProtKB:Q96QR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:B0035496 name: PURB_HUMAN-Phosphoserine304 def: "Protein PURB_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q96QR8] xref: UniProtKB:Q96QR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:B0035497 name: RAB8A_HUMAN-Phosphoserine181 def: "Protein RAB8A_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:P61006] xref: UniProtKB:P61006 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032548 ! RAB8A_HUMAN [Term] id: CCO:B0035498 name: RAB8A_HUMAN-Phosphoserine185 def: "Protein RAB8A_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:P61006] xref: UniProtKB:P61006 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032548 ! RAB8A_HUMAN [Term] id: CCO:B0035500 name: RALY_HUMAN-Phosphoserine135 def: "Protein RALY_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q9UKM9] xref: UniProtKB:Q9UKM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:B0035501 name: RALY_HUMAN-Phosphothreonine262 def: "Protein RALY_HUMAN with the residue 262 substituted with Phosphothreonine" [UniProtKB:Q9UKM9] comment: By similarity xref: UniProtKB:Q9UKM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:B0035502 name: RALY_HUMAN-Phosphoserine264 def: "Protein RALY_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q9UKM9] comment: By similarity xref: UniProtKB:Q9UKM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:B0035503 name: RALY_HUMAN-Phosphothreonine286 def: "Protein RALY_HUMAN with the residue 286 substituted with Phosphothreonine" [UniProtKB:Q9UKM9] xref: UniProtKB:Q9UKM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:B0035504 name: RALY_HUMAN-Phosphoserine288 def: "Protein RALY_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q9UKM9] xref: UniProtKB:Q9UKM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:B0035505 name: RALY_HUMAN-Phosphoserine295 def: "Protein RALY_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q9UKM9] xref: UniProtKB:Q9UKM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:B0035506 name: RALY_HUMAN-Phosphothreonine298 def: "Protein RALY_HUMAN with the residue 298 substituted with Phosphothreonine" [UniProtKB:Q9UKM9] xref: UniProtKB:Q9UKM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:B0035507 name: RAP1B_HUMAN-ADP-ribosylserine39 def: "Protein RAP1B_HUMAN with the residue 39 substituted with ADP-ribosylserine" [UniProtKB:P61224] comment: by botulinum toxin; Probable xref: UniProtKB:P61224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0024410 ! RAP1B_HUMAN [Term] id: CCO:B0035508 name: RAP1B_HUMAN-Phosphoserine179 def: "Protein RAP1B_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:P61224] comment: by PKA; xref: UniProtKB:P61224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024410 ! RAP1B_HUMAN [Term] id: CCO:B0035509 name: RAP1B_HUMAN-Cysteine methyl ester181 def: "Protein RAP1B_HUMAN with the residue 181 substituted with Cysteine methyl ester" [UniProtKB:P61224] xref: UniProtKB:P61224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024410 ! RAP1B_HUMAN [Term] id: CCO:B0035510 name: RAP2A_HUMAN-Cysteine methyl ester180 def: "Protein RAP2A_HUMAN with the residue 180 substituted with Cysteine methyl ester" [UniProtKB:P10114] comment: Probable xref: UniProtKB:P10114 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0024404 ! RAP2A_HUMAN [Term] id: CCO:B0035511 name: RAP2B_HUMAN-Cysteine methyl ester180 def: "Protein RAP2B_HUMAN with the residue 180 substituted with Cysteine methyl ester" [UniProtKB:P61225] comment: Probable xref: UniProtKB:P61225 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0024398 ! RAP2B_HUMAN [Term] id: CCO:B0035512 name: RAP2C_HUMAN-Cysteine methyl ester180 def: "Protein RAP2C_HUMAN with the residue 180 substituted with Cysteine methyl ester" [UniProtKB:Q9Y3L5] comment: By similarity xref: UniProtKB:Q9Y3L5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024407 ! RAP2C_HUMAN [Term] id: CCO:B0035538 name: RD23B_HUMAN-Phosphothreonine155 def: "Protein RD23B_HUMAN with the residue 155 substituted with Phosphothreonine" [UniProtKB:P54727] xref: UniProtKB:P54727 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020493 ! RD23B_HUMAN [Term] id: CCO:B0035539 name: RD23B_HUMAN-Phosphoserine160 def: "Protein RD23B_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:P54727] xref: UniProtKB:P54727 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0020493 ! RD23B_HUMAN [Term] id: CCO:B0035541 name: RFC3_HUMAN-Phosphoserine125 def: "Protein RFC3_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:P40938] xref: UniProtKB:P40938 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000281 ! DNA clamp loader activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000268 ! DNA replication factor C complex relationship: transformation_of CCO:B0026184 ! RFC3_HUMAN [Term] id: CCO:B0035550 name: RGS12_HUMAN-Phosphoserine874 def: "Protein RGS12_HUMAN with the residue 874 substituted with Phosphoserine" [UniProtKB:O14924] xref: UniProtKB:O14924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0033323 ! RGS12_HUMAN [Term] id: CCO:B0035551 name: RGS12_HUMAN-Phosphoserine889 def: "Protein RGS12_HUMAN with the residue 889 substituted with Phosphoserine" [UniProtKB:O14924] xref: UniProtKB:O14924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033323 ! RGS12_HUMAN [Term] id: CCO:B0035552 name: RGS12_HUMAN-Phosphoserine934 def: "Protein RGS12_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:O14924] xref: UniProtKB:O14924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033323 ! RGS12_HUMAN [Term] id: CCO:B0035553 name: RGS12_HUMAN-Phosphoserine940 def: "Protein RGS12_HUMAN with the residue 940 substituted with Phosphoserine" [UniProtKB:O14924] xref: UniProtKB:O14924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033323 ! RGS12_HUMAN [Term] id: CCO:B0035554 name: RGS16_HUMAN-Phosphotyrosine168 def: "Protein RGS16_HUMAN with the residue 168 substituted with Phosphotyrosine" [UniProtKB:O15492] comment: by EGFR; xref: UniProtKB:O15492 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020768 ! RGS16_HUMAN [Term] id: CCO:B0035555 name: RGS16_HUMAN-Phosphotyrosine177 def: "Protein RGS16_HUMAN with the residue 177 substituted with Phosphotyrosine" [UniProtKB:O15492] xref: UniProtKB:O15492 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020768 ! RGS16_HUMAN [Term] id: CCO:B0035556 name: RGS17_HUMAN-Phosphotyrosine137 def: "Protein RGS17_HUMAN with the residue 137 substituted with Phosphotyrosine" [UniProtKB:Q9UGC6] comment: By similarity xref: UniProtKB:Q9UGC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0026717 ! RGS17_HUMAN [Term] id: CCO:B0035557 name: RGS19_HUMAN-Phosphoserine24 def: "Protein RGS19_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:P49795] comment: By similarity xref: UniProtKB:P49795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0020776 ! RGS19_HUMAN [Term] id: CCO:B0035558 name: RGS19_HUMAN-Phosphoserine151 def: "Protein RGS19_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:P49795] comment: by MAPK1 and MAPK3; xref: UniProtKB:P49795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020776 ! RGS19_HUMAN [Term] id: CCO:B0035559 name: RGS1_HUMAN-Phosphoserine19 def: "Protein RGS1_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q08116] comment: by CK2; Potential xref: UniProtKB:Q08116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:B0035560 name: RGS1_HUMAN-Phosphoserine54 def: "Protein RGS1_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q08116] comment: by PKC; Potential xref: UniProtKB:Q08116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:B0035561 name: RGS1_HUMAN-Phosphoserine62 def: "Protein RGS1_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q08116] comment: by CK2; Potential xref: UniProtKB:Q08116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:B0035562 name: RGS1_HUMAN-Phosphothreonine146 def: "Protein RGS1_HUMAN with the residue 146 substituted with Phosphothreonine" [UniProtKB:Q08116] comment: by PKC; Potential xref: UniProtKB:Q08116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:B0035563 name: RGS1_HUMAN-Phosphothreonine156 def: "Protein RGS1_HUMAN with the residue 156 substituted with Phosphothreonine" [UniProtKB:Q08116] comment: by CK2; Potential xref: UniProtKB:Q08116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:B0035564 name: RGS1_HUMAN-Phosphothreonine167 def: "Protein RGS1_HUMAN with the residue 167 substituted with Phosphothreonine" [UniProtKB:Q08116] comment: by CK2; Potential xref: UniProtKB:Q08116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:B0035565 name: RGS1_HUMAN-Phosphoserine194 def: "Protein RGS1_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q08116] comment: by PKC; Potential xref: UniProtKB:Q08116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:B0035566 name: RGS3_HUMAN-Phosphoserine943 def: "Protein RGS3_HUMAN with the residue 943 substituted with Phosphoserine" [UniProtKB:P49796] comment: By similarity xref: UniProtKB:P49796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020771 ! RGS3_HUMAN [Term] id: CCO:B0035567 name: RGS3_HUMAN-Phosphoserine946 def: "Protein RGS3_HUMAN with the residue 946 substituted with Phosphoserine" [UniProtKB:P49796] comment: By similarity xref: UniProtKB:P49796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020771 ! RGS3_HUMAN [Term] id: CCO:B0035568 name: RHG07_HUMAN-Phosphoserine86 def: "Protein RHG07_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035569 name: RHG07_HUMAN-Phosphoserine89 def: "Protein RHG07_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035570 name: RHG07_HUMAN-Phosphoserine304 def: "Protein RHG07_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035571 name: RHG07_HUMAN-Phosphoserine305 def: "Protein RHG07_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004517 ! Rac GTPase activator activity relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000477 ! focal adhesion relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035572 name: RHG07_HUMAN-Phosphoserine310 def: "Protein RHG07_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035573 name: RHG07_HUMAN-Phosphothreonine312 def: "Protein RHG07_HUMAN with the residue 312 substituted with Phosphothreonine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035574 name: RHG07_HUMAN-Phosphoserine313 def: "Protein RHG07_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035575 name: RHG07_HUMAN-Phosphoserine317 def: "Protein RHG07_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035576 name: RHG07_HUMAN-Phosphothreonine318 def: "Protein RHG07_HUMAN with the residue 318 substituted with Phosphothreonine" [UniProtKB:Q96QB1] comment: By similarity xref: UniProtKB:Q96QB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:B0035577 name: RHG28_HUMAN-Phosphothreonine155 def: "Protein RHG28_HUMAN with the residue 155 substituted with Phosphothreonine" [UniProtKB:Q9P2N2] comment: By similarity xref: UniProtKB:Q9P2N2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034094 ! RHG28_HUMAN [Term] id: CCO:B0035578 name: RHG28_HUMAN-Phosphothreonine157 def: "Protein RHG28_HUMAN with the residue 157 substituted with Phosphothreonine" [UniProtKB:Q9P2N2] comment: By similarity xref: UniProtKB:Q9P2N2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034094 ! RHG28_HUMAN [Term] id: CCO:B0035579 name: RHG28_HUMAN-Phosphothreonine159 def: "Protein RHG28_HUMAN with the residue 159 substituted with Phosphothreonine" [UniProtKB:Q9P2N2] comment: By similarity xref: UniProtKB:Q9P2N2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034094 ! RHG28_HUMAN [Term] id: CCO:B0035580 name: RING2_HUMAN-Phosphoserine168 def: "Protein RING2_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q99496] xref: UniProtKB:Q99496 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020552 ! RING2_HUMAN [Term] id: CCO:B0035589 name: RIR2_HUMAN-Phosphoserine20 def: "Protein RIR2_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P31350] xref: UniProtKB:P31350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030757 ! RIR2_HUMAN [Term] id: CCO:B0035592 name: RND1_HUMAN-Cysteine methyl ester229 def: "Protein RND1_HUMAN with the residue 229 substituted with Cysteine methyl ester" [UniProtKB:Q92730] comment: By similarity xref: UniProtKB:Q92730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030278 ! RND1_HUMAN [Term] id: CCO:B0035593 name: RND2_HUMAN-Cysteine methyl ester224 def: "Protein RND2_HUMAN with the residue 224 substituted with Cysteine methyl ester" [UniProtKB:P52198] comment: By similarity xref: UniProtKB:P52198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030280 ! RND2_HUMAN [Term] id: CCO:B0035594 name: RND3_HUMAN-Cysteine methyl ester241 def: "Protein RND3_HUMAN with the residue 241 substituted with Cysteine methyl ester" [UniProtKB:P61587] comment: By similarity xref: UniProtKB:P61587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0030277 ! RND3_HUMAN [Term] id: CCO:B0035598 name: RRAS2_HUMAN-Phosphoserine186 def: "Protein RRAS2_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:P62070] xref: UniProtKB:P62070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018011 ! RRAS2_HUMAN [Term] id: CCO:B0035599 name: RRAS2_HUMAN-Cysteine methyl ester201 def: "Protein RRAS2_HUMAN with the residue 201 substituted with Cysteine methyl ester" [UniProtKB:P62070] comment: Probable xref: UniProtKB:P62070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0018011 ! RRAS2_HUMAN [Term] id: CCO:B0035600 name: RRAS_HUMAN-Cysteine methyl ester215 def: "Protein RRAS_HUMAN with the residue 215 substituted with Cysteine methyl ester" [UniProtKB:P10301] comment: By similarity xref: UniProtKB:P10301 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0018007 ! RRAS_HUMAN [Term] id: CCO:B0035601 name: RS27_HUMAN-Phosphoserine11 def: "Protein RS27_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P42677] xref: UniProtKB:P42677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:B0035602 name: RS27_HUMAN-Phosphotyrosine31 def: "Protein RS27_HUMAN with the residue 31 substituted with Phosphotyrosine" [UniProtKB:P42677] xref: UniProtKB:P42677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:B0035603 name: RS27_HUMAN-Phosphoserine78 def: "Protein RS27_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:P42677] xref: UniProtKB:P42677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:B0035604 name: RS3_HUMAN-Phosphothreonine221 def: "Protein RS3_HUMAN with the residue 221 substituted with Phosphothreonine" [UniProtKB:P23396] xref: UniProtKB:P23396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:B0035605 name: RS3_HUMAN-Phosphoserine224 def: "Protein RS3_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:P23396] xref: UniProtKB:P23396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:B0035609 name: RUNX1_HUMAN-Phosphothreonine14 def: "Protein RUNX1_HUMAN with the residue 14 substituted with Phosphothreonine" [UniProtKB:Q01196] xref: UniProtKB:Q01196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033619 ! RUNX1_HUMAN [Term] id: CCO:B0035610 name: RUNX1_HUMAN-Phosphoserine21 def: "Protein RUNX1_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q01196] xref: UniProtKB:Q01196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0033619 ! RUNX1_HUMAN [Term] id: CCO:B0035624 name: SCND2_HUMAN-Phosphoserine260 def: "Protein SCND2_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:Q9GZW5] xref: UniProtKB:Q9GZW5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021156 ! SCND2_HUMAN [Term] id: CCO:B0035630 name: SET1B_HUMAN-Phosphoserine1616 def: "Protein SET1B_HUMAN with the residue 1616 substituted with Phosphoserine" [UniProtKB:Q9UPS6] xref: UniProtKB:Q9UPS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034353 ! SET1B_HUMAN [Term] id: CCO:B0035631 name: SET1B_HUMAN-Phosphoserine1620 def: "Protein SET1B_HUMAN with the residue 1620 substituted with Phosphoserine" [UniProtKB:Q9UPS6] xref: UniProtKB:Q9UPS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034353 ! SET1B_HUMAN [Term] id: CCO:B0035648 name: SGK2_HUMAN-Phosphothreonine253 def: "Protein SGK2_HUMAN with the residue 253 substituted with Phosphothreonine" [UniProtKB:Q9HBY8] comment: by PDPK1; xref: UniProtKB:Q9HBY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033210 ! SGK2_HUMAN [Term] id: CCO:B0035649 name: SGK2_HUMAN-Phosphoserine416 def: "Protein SGK2_HUMAN with the residue 416 substituted with Phosphoserine" [UniProtKB:Q9HBY8] comment: Potential xref: UniProtKB:Q9HBY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001052 ! protein kinase CK2 activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002867 ! potassium channel regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003551 ! sodium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0033210 ! SGK2_HUMAN [Term] id: CCO:B0035657 name: SI1L2_HUMAN-Phosphoserine1406 def: "Protein SI1L2_HUMAN with the residue 1406 substituted with Phosphoserine" [UniProtKB:Q9P2F8] comment: By similarity xref: UniProtKB:Q9P2F8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023489 ! SI1L2_HUMAN [Term] id: CCO:B0035665 name: SMAP2_HUMAN-Phosphoserine219 def: "Protein SMAP2_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q8WU79] xref: UniProtKB:Q8WU79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0033514 ! SMAP2_HUMAN [Term] id: CCO:B0035666 name: SMAP2_HUMAN-Phosphoserine240 def: "Protein SMAP2_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q8WU79] comment: By similarity xref: UniProtKB:Q8WU79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033514 ! SMAP2_HUMAN [Term] id: CCO:B0035670 name: SODC_HUMAN-N-acetylalanine2 def: "Protein SODC_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P00441] xref: UniProtKB:P00441 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033014 ! SODC_HUMAN [Term] id: CCO:B0035671 name: SODC_HUMAN-N6-acetyllysine71 def: "Protein SODC_HUMAN with the residue 71 substituted with N6-acetyllysine" [UniProtKB:P00441] comment: By similarity xref: UniProtKB:P00441 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033014 ! SODC_HUMAN [Term] id: CCO:B0035672 name: SODM_HUMAN-N6-acetyllysine68 def: "Protein SODM_HUMAN with the residue 68 substituted with N6-acetyllysine" [UniProtKB:P04179] comment: By similarity xref: UniProtKB:P04179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001144 ! superoxide dismutase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0033778 ! SODM_HUMAN [Term] id: CCO:B0035673 name: SOX11_HUMAN-Phosphoserine278 def: "Protein SOX11_HUMAN with the residue 278 substituted with Phosphoserine" [UniProtKB:P35716] comment: By similarity xref: UniProtKB:P35716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0020254 ! SOX11_HUMAN [Term] id: CCO:B0035674 name: SOX4_HUMAN-Phosphoserine276 def: "Protein SOX4_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q06945] comment: By similarity xref: UniProtKB:Q06945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020292 ! SOX4_HUMAN [Term] id: CCO:B0035675 name: SP16H_HUMAN-Phosphoserine979 def: "Protein SP16H_HUMAN with the residue 979 substituted with Phosphoserine" [UniProtKB:Q9Y5B9] xref: UniProtKB:Q9Y5B9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032537 ! SP16H_HUMAN [Term] id: CCO:B0035676 name: SP16H_HUMAN-Phosphoserine982 def: "Protein SP16H_HUMAN with the residue 982 substituted with Phosphoserine" [UniProtKB:Q9Y5B9] xref: UniProtKB:Q9Y5B9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032537 ! SP16H_HUMAN [Term] id: CCO:B0035677 name: SP16H_HUMAN-Phosphoserine986 def: "Protein SP16H_HUMAN with the residue 986 substituted with Phosphoserine" [UniProtKB:Q9Y5B9] xref: UniProtKB:Q9Y5B9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032537 ! SP16H_HUMAN [Term] id: CCO:B0035681 name: SRF_HUMAN-Phosphotyrosine76 def: "Protein SRF_HUMAN with the residue 76 substituted with Phosphotyrosine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035682 name: SRF_HUMAN-Phosphoserine77 def: "Protein SRF_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035683 name: SRF_HUMAN-Phosphoserine79 def: "Protein SRF_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035684 name: SRF_HUMAN-Phosphoserine83 def: "Protein SRF_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035685 name: SRF_HUMAN-Phosphoserine85 def: "Protein SRF_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035686 name: SRF_HUMAN-Phosphoserine103 def: "Protein SRF_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035687 name: SRF_HUMAN-Phosphoserine224 def: "Protein SRF_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035688 name: SRF_HUMAN-Phosphoserine253 def: "Protein SRF_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:P11831] xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035689 name: SRF_HUMAN-Phosphoserine435 def: "Protein SRF_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:P11831] comment: by dsDNA kinase; xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035690 name: SRF_HUMAN-Phosphoserine446 def: "Protein SRF_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:P11831] comment: by dsDNA kinase; xref: UniProtKB:P11831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028347 ! SRF_HUMAN [Term] id: CCO:B0035691 name: SRPK2_HUMAN-Phosphoserine52 def: "Protein SRPK2_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:P78362] comment: by CK2; By similarity xref: UniProtKB:P78362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022813 ! SRPK2_HUMAN [Term] id: CCO:B0035692 name: SRPK2_HUMAN-Phosphotyrosine319 def: "Protein SRPK2_HUMAN with the residue 319 substituted with Phosphotyrosine" [UniProtKB:P78362] xref: UniProtKB:P78362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0022813 ! SRPK2_HUMAN [Term] id: CCO:B0035693 name: SRPK2_HUMAN-Phosphoserine588 def: "Protein SRPK2_HUMAN with the residue 588 substituted with Phosphoserine" [UniProtKB:P78362] comment: by CK2; By similarity xref: UniProtKB:P78362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022813 ! SRPK2_HUMAN [Term] id: CCO:B0035694 name: SRY_HUMAN-N6-acetyllysine136 def: "Protein SRY_HUMAN with the residue 136 substituted with N6-acetyllysine" [UniProtKB:Q05066] xref: UniProtKB:Q05066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020282 ! SRY_HUMAN [Term] id: CCO:B0035695 name: ST38L_HUMAN-Phosphothreonine75 def: "Protein ST38L_HUMAN with the residue 75 substituted with Phosphothreonine" [UniProtKB:Q9Y2H1] xref: UniProtKB:Q9Y2H1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015573 ! ST38L_HUMAN [Term] id: CCO:B0035696 name: ST38L_HUMAN-Phosphoserine282 def: "Protein ST38L_HUMAN with the residue 282 substituted with Phosphoserine" [UniProtKB:Q9Y2H1] comment: by autocatalysis; xref: UniProtKB:Q9Y2H1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0015573 ! ST38L_HUMAN [Term] id: CCO:B0035697 name: ST38L_HUMAN-Phosphothreonine442 def: "Protein ST38L_HUMAN with the residue 442 substituted with Phosphothreonine" [UniProtKB:Q9Y2H1] xref: UniProtKB:Q9Y2H1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015573 ! ST38L_HUMAN [Term] id: CCO:B0035698 name: ST38L_HUMAN-Phosphothreonine450 def: "Protein ST38L_HUMAN with the residue 450 substituted with Phosphothreonine" [UniProtKB:Q9Y2H1] comment: By similarity xref: UniProtKB:Q9Y2H1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015573 ! ST38L_HUMAN [Term] id: CCO:B0035699 name: STAT6_HUMAN-Phosphotyrosine641 def: "Protein STAT6_HUMAN with the residue 641 substituted with Phosphotyrosine" [UniProtKB:P42226] comment: by JAK; By similarity xref: UniProtKB:P42226 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0029685 ! STAT6_HUMAN [Term] id: CCO:B0035700 name: STK24_HUMAN-Phosphothreonine18 def: "Protein STK24_HUMAN with the residue 18 substituted with Phosphothreonine" [UniProtKB:Q9Y6E0] comment: by PKA; xref: UniProtKB:Q9Y6E0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0022743 ! STK24_HUMAN [Term] id: CCO:B0035701 name: STK24_HUMAN-Phosphoserine311 def: "Protein STK24_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q9Y6E0] xref: UniProtKB:Q9Y6E0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022743 ! STK24_HUMAN [Term] id: CCO:B0035702 name: STK24_HUMAN-Phosphoserine315 def: "Protein STK24_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q9Y6E0] xref: UniProtKB:Q9Y6E0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022743 ! STK24_HUMAN [Term] id: CCO:B0035703 name: STK24_HUMAN-Phosphoserine316 def: "Protein STK24_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q9Y6E0] xref: UniProtKB:Q9Y6E0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022743 ! STK24_HUMAN [Term] id: CCO:B0035704 name: STK24_HUMAN-Phosphoserine317 def: "Protein STK24_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q9Y6E0] xref: UniProtKB:Q9Y6E0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022743 ! STK24_HUMAN [Term] id: CCO:B0035705 name: STK24_HUMAN-Phosphoserine320 def: "Protein STK24_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q9Y6E0] xref: UniProtKB:Q9Y6E0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022743 ! STK24_HUMAN [Term] id: CCO:B0035706 name: STK25_HUMAN-Phosphothreonine168 def: "Protein STK25_HUMAN with the residue 168 substituted with Phosphothreonine" [UniProtKB:O00506] xref: UniProtKB:O00506 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022748 ! STK25_HUMAN [Term] id: CCO:B0035707 name: STK25_HUMAN-Phosphothreonine174 def: "Protein STK25_HUMAN with the residue 174 substituted with Phosphothreonine" [UniProtKB:O00506] comment: by autocatalysis; xref: UniProtKB:O00506 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0022748 ! STK25_HUMAN [Term] id: CCO:B0035708 name: STK25_HUMAN-Phosphoserine342 def: "Protein STK25_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:O00506] xref: UniProtKB:O00506 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022748 ! STK25_HUMAN [Term] id: CCO:B0035709 name: STK38_HUMAN-Phosphothreonine74 def: "Protein STK38_HUMAN with the residue 74 substituted with Phosphothreonine" [UniProtKB:Q15208] xref: UniProtKB:Q15208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015584 ! STK38_HUMAN [Term] id: CCO:B0035710 name: STK38_HUMAN-Phosphoserine281 def: "Protein STK38_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q15208] comment: by autocatalysis; xref: UniProtKB:Q15208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015584 ! STK38_HUMAN [Term] id: CCO:B0035711 name: STK38_HUMAN-Phosphothreonine444 def: "Protein STK38_HUMAN with the residue 444 substituted with Phosphothreonine" [UniProtKB:Q15208] xref: UniProtKB:Q15208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015584 ! STK38_HUMAN [Term] id: CCO:B0035712 name: STMN2_HUMAN-Phosphoserine16 def: "Protein STMN2_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q93045] comment: Potential xref: UniProtKB:Q93045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:B0035713 name: STMN2_HUMAN-Phosphoserine50 def: "Protein STMN2_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q93045] comment: Potential xref: UniProtKB:Q93045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:B0035714 name: STMN2_HUMAN-Phosphoserine62 def: "Protein STMN2_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q93045] comment: Potential xref: UniProtKB:Q93045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:B0035715 name: STMN2_HUMAN-Phosphoserine73 def: "Protein STMN2_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:Q93045] comment: Potential xref: UniProtKB:Q93045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:B0035716 name: STMN2_HUMAN-Phosphoserine80 def: "Protein STMN2_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q93045] xref: UniProtKB:Q93045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:B0035717 name: STMN2_HUMAN-Phosphoserine97 def: "Protein STMN2_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q93045] comment: Potential xref: UniProtKB:Q93045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:B0035718 name: STMN3_HUMAN-Phosphoserine65 def: "Protein STMN3_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q9NZ72] comment: By similarity xref: UniProtKB:Q9NZ72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023039 ! STMN3_HUMAN [Term] id: CCO:B0035719 name: STMN3_HUMAN-Phosphoserine68 def: "Protein STMN3_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:Q9NZ72] comment: By similarity xref: UniProtKB:Q9NZ72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0023039 ! STMN3_HUMAN [Term] id: CCO:B0035720 name: STMN3_HUMAN-Phosphoserine73 def: "Protein STMN3_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:Q9NZ72] comment: By similarity xref: UniProtKB:Q9NZ72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023039 ! STMN3_HUMAN [Term] id: CCO:B0035722 name: SYWC_HUMAN-Phosphoserine467 def: "Protein SYWC_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:P23381] xref: UniProtKB:P23381 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021811 ! SYWC_HUMAN [Term] id: CCO:B0035723 name: TAF9B_HUMAN-Phosphothreonine156 def: "Protein TAF9B_HUMAN with the residue 156 substituted with Phosphothreonine" [UniProtKB:Q9HBM6] comment: By similarity xref: UniProtKB:Q9HBM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014928 ! TAF9B_HUMAN [Term] id: CCO:B0035724 name: TB182_HUMAN-Phosphoserine221 def: "Protein TB182_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035725 name: TB182_HUMAN-Phosphoserine228 def: "Protein TB182_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035726 name: TB182_HUMAN-Phosphoserine601 def: "Protein TB182_HUMAN with the residue 601 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035727 name: TB182_HUMAN-Phosphoserine672 def: "Protein TB182_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035728 name: TB182_HUMAN-Phosphoserine691 def: "Protein TB182_HUMAN with the residue 691 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035729 name: TB182_HUMAN-Phosphoserine695 def: "Protein TB182_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035730 name: TB182_HUMAN-Phosphoserine806 def: "Protein TB182_HUMAN with the residue 806 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035731 name: TB182_HUMAN-Phosphothreonine833 def: "Protein TB182_HUMAN with the residue 833 substituted with Phosphothreonine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035732 name: TB182_HUMAN-Phosphoserine836 def: "Protein TB182_HUMAN with the residue 836 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035733 name: TB182_HUMAN-Phosphoserine872 def: "Protein TB182_HUMAN with the residue 872 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035734 name: TB182_HUMAN-Phosphoserine893 def: "Protein TB182_HUMAN with the residue 893 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035735 name: TB182_HUMAN-Phosphoserine920 def: "Protein TB182_HUMAN with the residue 920 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035736 name: TB182_HUMAN-Phosphoserine936 def: "Protein TB182_HUMAN with the residue 936 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035737 name: TB182_HUMAN-Phosphoserine1093 def: "Protein TB182_HUMAN with the residue 1093 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035738 name: TB182_HUMAN-Phosphoserine1103 def: "Protein TB182_HUMAN with the residue 1103 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035739 name: TB182_HUMAN-Phosphoserine1138 def: "Protein TB182_HUMAN with the residue 1138 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035740 name: TB182_HUMAN-Phosphoserine1248 def: "Protein TB182_HUMAN with the residue 1248 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035741 name: TB182_HUMAN-Phosphoserine1331 def: "Protein TB182_HUMAN with the residue 1331 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035742 name: TB182_HUMAN-Phosphoserine1383 def: "Protein TB182_HUMAN with the residue 1383 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035743 name: TB182_HUMAN-Phosphoserine1385 def: "Protein TB182_HUMAN with the residue 1385 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035744 name: TB182_HUMAN-Phosphoserine1452 def: "Protein TB182_HUMAN with the residue 1452 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035745 name: TB182_HUMAN-Phosphoserine1554 def: "Protein TB182_HUMAN with the residue 1554 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035746 name: TB182_HUMAN-Phosphoserine1620 def: "Protein TB182_HUMAN with the residue 1620 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035747 name: TB182_HUMAN-Phosphoserine1621 def: "Protein TB182_HUMAN with the residue 1621 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004447 ! ankyrin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000314 ! nuclear telomeric heterochromatin relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035748 name: TB182_HUMAN-Phosphoserine1654 def: "Protein TB182_HUMAN with the residue 1654 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035749 name: TB182_HUMAN-Phosphoserine1666 def: "Protein TB182_HUMAN with the residue 1666 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0035753 name: TBA3C_HUMAN-Phosphoserine48 def: "Protein TBA3C_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q13748] xref: UniProtKB:Q13748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:B0035755 name: TBA8_HUMAN-Phosphotyrosine103 def: "Protein TBA8_HUMAN with the residue 103 substituted with Phosphotyrosine" [UniProtKB:Q9NY65] comment: By similarity xref: UniProtKB:Q9NY65 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024578 ! TBA8_HUMAN [Term] id: CCO:B0035756 name: TBA8_HUMAN-Phosphotyrosine357 def: "Protein TBA8_HUMAN with the residue 357 substituted with Phosphotyrosine" [UniProtKB:Q9NY65] comment: By similarity xref: UniProtKB:Q9NY65 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024578 ! TBA8_HUMAN [Term] id: CCO:B0035757 name: TBB2C_HUMAN-Phosphotyrosine51 def: "Protein TBB2C_HUMAN with the residue 51 substituted with Phosphotyrosine" [UniProtKB:P68371] comment: By similarity xref: UniProtKB:P68371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019878 ! TBB2C_HUMAN [Term] id: CCO:B0035758 name: TBB2C_HUMAN-Phosphoserine172 def: "Protein TBB2C_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:P68371] xref: UniProtKB:P68371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019878 ! TBB2C_HUMAN [Term] id: CCO:B0035759 name: TBB6_HUMAN-Phosphoserine56 def: "Protein TBB6_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:Q9BUF5] xref: UniProtKB:Q9BUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019883 ! TBB6_HUMAN [Term] id: CCO:B0035760 name: TBB6_HUMAN-Phosphotyrosine106 def: "Protein TBB6_HUMAN with the residue 106 substituted with Phosphotyrosine" [UniProtKB:Q9BUF5] comment: By similarity xref: UniProtKB:Q9BUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019883 ! TBB6_HUMAN [Term] id: CCO:B0035761 name: TBC13_HUMAN-Phosphothreonine96 def: "Protein TBC13_HUMAN with the residue 96 substituted with Phosphothreonine" [UniProtKB:Q9NVG8] xref: UniProtKB:Q9NVG8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031754 ! TBC13_HUMAN [Term] id: CCO:B0035762 name: TBC13_HUMAN-Phosphoserine108 def: "Protein TBC13_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q9NVG8] xref: UniProtKB:Q9NVG8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0031754 ! TBC13_HUMAN [Term] id: CCO:B0035763 name: TCPQ_HUMAN-N-acetylalanine2 def: "Protein TCPQ_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P50990] xref: UniProtKB:P50990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:B0035764 name: TCPQ_HUMAN-N6-acetyllysine20 def: "Protein TCPQ_HUMAN with the residue 20 substituted with N6-acetyllysine" [UniProtKB:P50990] xref: UniProtKB:P50990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:B0035765 name: TCPQ_HUMAN-Phosphothreonine227 def: "Protein TCPQ_HUMAN with the residue 227 substituted with Phosphothreonine" [UniProtKB:P50990] xref: UniProtKB:P50990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:B0035766 name: TCPQ_HUMAN-Phosphothreonine232 def: "Protein TCPQ_HUMAN with the residue 232 substituted with Phosphothreonine" [UniProtKB:P50990] xref: UniProtKB:P50990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:B0035767 name: TCPQ_HUMAN-Phosphoserine233 def: "Protein TCPQ_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:P50990] xref: UniProtKB:P50990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:B0035768 name: TCPQ_HUMAN-Phosphotyrosine505 def: "Protein TCPQ_HUMAN with the residue 505 substituted with Phosphotyrosine" [UniProtKB:P50990] xref: UniProtKB:P50990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:B0035769 name: TERA_HUMAN-N-acetylalanine2 def: "Protein TERA_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P55072] xref: UniProtKB:P55072 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:B0035770 name: TERA_HUMAN-Phosphoserine7 def: "Protein TERA_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:P55072] comment: By similarity xref: UniProtKB:P55072 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:B0035771 name: TERA_HUMAN-Phosphoserine784 def: "Protein TERA_HUMAN with the residue 784 substituted with Phosphoserine" [UniProtKB:P55072] xref: UniProtKB:P55072 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:B0035772 name: TERA_HUMAN-Phosphotyrosine805 def: "Protein TERA_HUMAN with the residue 805 substituted with Phosphotyrosine" [UniProtKB:P55072] xref: UniProtKB:P55072 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:B0035773 name: TGFI1_HUMAN-Phosphotyrosine38 def: "Protein TGFI1_HUMAN with the residue 38 substituted with Phosphotyrosine" [UniProtKB:O43294] comment: By similarity xref: UniProtKB:O43294 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0017844 ! TGFI1_HUMAN [Term] id: CCO:B0035774 name: TGFI1_HUMAN-Phosphotyrosine60 def: "Protein TGFI1_HUMAN with the residue 60 substituted with Phosphotyrosine" [UniProtKB:O43294] comment: by FAK2 and FYN; xref: UniProtKB:O43294 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017844 ! TGFI1_HUMAN [Term] id: CCO:B0035775 name: TGFI1_HUMAN-Phosphoserine68 def: "Protein TGFI1_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:O43294] xref: UniProtKB:O43294 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017844 ! TGFI1_HUMAN [Term] id: CCO:B0035776 name: TGFI1_HUMAN-Phosphoserine122 def: "Protein TGFI1_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:O43294] xref: UniProtKB:O43294 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017844 ! TGFI1_HUMAN [Term] id: CCO:B0035777 name: TGIF2_HUMAN-Phosphothreonine182 def: "Protein TGIF2_HUMAN with the residue 182 substituted with Phosphothreonine" [UniProtKB:Q9GZN2] xref: UniProtKB:Q9GZN2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021266 ! TGIF2_HUMAN [Term] id: CCO:B0035778 name: TGIF2_HUMAN-Phosphothreonine186 def: "Protein TGIF2_HUMAN with the residue 186 substituted with Phosphothreonine" [UniProtKB:Q9GZN2] xref: UniProtKB:Q9GZN2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021266 ! TGIF2_HUMAN [Term] id: CCO:B0035779 name: THOC4_HUMAN-N-acetylalanine2 def: "Protein THOC4_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q86V81] xref: UniProtKB:Q86V81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017403 ! THOC4_HUMAN [Term] id: CCO:B0035780 name: THOC4_HUMAN-Omega-N-methylated arginine50 def: "Protein THOC4_HUMAN with the residue 50 substituted with Omega-N-methylated arginine" [UniProtKB:Q86V81] xref: UniProtKB:Q86V81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017403 ! THOC4_HUMAN [Term] id: CCO:B0035781 name: THOC4_HUMAN-Phosphoserine183 def: "Protein THOC4_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q86V81] xref: UniProtKB:Q86V81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0017403 ! THOC4_HUMAN [Term] id: CCO:B0035782 name: THOC4_HUMAN-Omega-N-methylated arginine204 def: "Protein THOC4_HUMAN with the residue 204 substituted with Omega-N-methylated arginine" [UniProtKB:Q86V81] xref: UniProtKB:Q86V81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017403 ! THOC4_HUMAN [Term] id: CCO:B0035783 name: TICN2_HUMAN-Phosphothreonine86 def: "Protein TICN2_HUMAN with the residue 86 substituted with Phosphothreonine" [UniProtKB:Q92563] xref: UniProtKB:Q92563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: transformation_of CCO:B0026671 ! TICN2_HUMAN [Term] id: CCO:B0035785 name: TISB_HUMAN-Phosphoserine54 def: "Protein TISB_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q07352] comment: By similarity xref: UniProtKB:Q07352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0026498 ! TISB_HUMAN [Term] id: CCO:B0035786 name: TISB_HUMAN-Phosphoserine92 def: "Protein TISB_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q07352] comment: By similarity xref: UniProtKB:Q07352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026498 ! TISB_HUMAN [Term] id: CCO:B0035812 name: TPIS_HUMAN-Phosphoserine21 def: "Protein TPIS_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P60174] xref: UniProtKB:P60174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001165 ! triose-phosphate isomerase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0015866 ! TPIS_HUMAN [Term] id: CCO:B0035813 name: TPIS_HUMAN-N6-acetyllysine188 def: "Protein TPIS_HUMAN with the residue 188 substituted with N6-acetyllysine" [UniProtKB:P60174] xref: UniProtKB:P60174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015866 ! TPIS_HUMAN [Term] id: CCO:B0035816 name: TRPC4_HUMAN-Phosphoserine193 def: "Protein TRPC4_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:Q9UBN4] xref: UniProtKB:Q9UBN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025166 ! TRPC4_HUMAN [Term] id: CCO:B0035817 name: TRPC4_HUMAN-Phosphoserine195 def: "Protein TRPC4_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:Q9UBN4] xref: UniProtKB:Q9UBN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002736 ! store-operated calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001055 ! cortical cytoskeleton relationship: transformation_of CCO:B0025166 ! TRPC4_HUMAN [Term] id: CCO:B0035818 name: U520_HUMAN-Phosphoserine225 def: "Protein U520_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:O75643] xref: UniProtKB:O75643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020984 ! U520_HUMAN [Term] id: CCO:B0035819 name: U520_HUMAN-Phosphoserine756 def: "Protein U520_HUMAN with the residue 756 substituted with Phosphoserine" [UniProtKB:O75643] xref: UniProtKB:O75643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020984 ! U520_HUMAN [Term] id: CCO:B0035820 name: U520_HUMAN-Phosphoserine1056 def: "Protein U520_HUMAN with the residue 1056 substituted with Phosphoserine" [UniProtKB:O75643] xref: UniProtKB:O75643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000284 ! snRNP U5 relationship: transformation_of CCO:B0020984 ! U520_HUMAN [Term] id: CCO:B0035826 name: UK114_HUMAN-Phosphotyrosine21 def: "Protein UK114_HUMAN with the residue 21 substituted with Phosphotyrosine" [UniProtKB:P52758] comment: By similarity xref: UniProtKB:P52758 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026435 ! UK114_HUMAN [Term] id: CCO:B0035829 name: WDHD1_HUMAN-Phosphoserine374 def: "Protein WDHD1_HUMAN with the residue 374 substituted with Phosphoserine" [UniProtKB:O75717] xref: UniProtKB:O75717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0019767 ! WDHD1_HUMAN [Term] id: CCO:B0035830 name: WDHD1_HUMAN-Phosphoserine383 def: "Protein WDHD1_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:O75717] xref: UniProtKB:O75717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019767 ! WDHD1_HUMAN [Term] id: CCO:B0035831 name: WDHD1_HUMAN-Phosphothreonine826 def: "Protein WDHD1_HUMAN with the residue 826 substituted with Phosphothreonine" [UniProtKB:O75717] xref: UniProtKB:O75717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019767 ! WDHD1_HUMAN [Term] id: CCO:B0035832 name: WDHD1_HUMAN-Phosphoserine868 def: "Protein WDHD1_HUMAN with the residue 868 substituted with Phosphoserine" [UniProtKB:O75717] xref: UniProtKB:O75717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019767 ! WDHD1_HUMAN [Term] id: CCO:B0035833 name: WDHD1_HUMAN-Phosphoserine1041 def: "Protein WDHD1_HUMAN with the residue 1041 substituted with Phosphoserine" [UniProtKB:O75717] xref: UniProtKB:O75717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019767 ! WDHD1_HUMAN [Term] id: CCO:B0035836 name: XRCC1_HUMAN-Phosphoserine266 def: "Protein XRCC1_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035837 name: XRCC1_HUMAN-Phosphoserine371 def: "Protein XRCC1_HUMAN with the residue 371 substituted with Phosphoserine" [UniProtKB:P18887] comment: by PRKDC; xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035838 name: XRCC1_HUMAN-Phosphoserine408 def: "Protein XRCC1_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035839 name: XRCC1_HUMAN-Phosphoserine409 def: "Protein XRCC1_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035840 name: XRCC1_HUMAN-Phosphoserine410 def: "Protein XRCC1_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035841 name: XRCC1_HUMAN-Phosphoserine416 def: "Protein XRCC1_HUMAN with the residue 416 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035842 name: XRCC1_HUMAN-Phosphoserine418 def: "Protein XRCC1_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035843 name: XRCC1_HUMAN-Phosphoserine421 def: "Protein XRCC1_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035844 name: XRCC1_HUMAN-Phosphoserine447 def: "Protein XRCC1_HUMAN with the residue 447 substituted with Phosphoserine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035845 name: XRCC1_HUMAN-Phosphothreonine453 def: "Protein XRCC1_HUMAN with the residue 453 substituted with Phosphothreonine" [UniProtKB:P18887] xref: UniProtKB:P18887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:B0035935 name: MEN1_HUMAN def: "Menin" [UniProtKB:O00255] xref: EMBL:AAC51228.1 xref: EMBL:AAC51229.1 xref: EMBL:AAC51230.1 xref: EMBL:AAH02544.1 xref: UniProtKB:O00255 xref: UniProtKB:O00632 xref: UniProtKB:Q9BUK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010895 ! MEN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006305 ! mll-hcfc2-2 physical interaction relationship: participates_in CCO:I0008564 ! menin-myh9-1 physical interaction relationship: participates_in CCO:I0008567 ! menin-myh9-6 physical interaction relationship: participates_in CCO:I0008569 ! mll-hcfc2-1 physical interaction relationship: participates_in CCO:I0008576 ! menin-myh9-4 direct interaction relationship: participates_in CCO:I0008577 ! myh9-menin-1 direct interaction relationship: participates_in CCO:I0008579 ! menin-myh9-3 physical interaction relationship: participates_in CCO:I0008581 ! menin-myh9-2 physical interaction relationship: participates_in CCO:I0008582 ! menin-myh9-5 colocalization relationship: participates_in CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000501 ! negative regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001272 ! positive regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: participates_in CCO:P0002482 ! negative regulation of osteoblast differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002690 ! negative regulation of JNK cascade relationship: transforms_into CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 [Term] id: CCO:B0035936 name: RNF8_HUMAN def: "E3 ubiquitin-protein ligase RNF8" [UniProtKB:O76064] synonym: "EC 6.3.2.-" EXACT [UniProtKB:O76064] synonym: "RING finger protein 8" EXACT [UniProtKB:O76064] xref: EMBL:AAH07517.1 xref: EMBL:AAP36114.1 xref: EMBL:AAQ14887.1 xref: EMBL:BAA31621.2 xref: EMBL:BAA33557.1 xref: EMBL:BAD96485.1 xref: EMBL:CAB75689.1 xref: EMBL:EAX03944.1 xref: UniProtKB:O76064 xref: UniProtKB:Q53H16 xref: UniProtKB:Q5NKW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010897 ! RNF8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008568 ! rrp4-rnf8 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0035937 name: S26A8_HUMAN def: "Testis anion transporter 1" [UniProtKB:Q96RN1] synonym: "Anion exchange transporter" EXACT [UniProtKB:Q96RN1] synonym: "Solute carrier family 26 member 8" EXACT [UniProtKB:Q96RN1] xref: EMBL:AAH25408.1 xref: EMBL:AAK95666.1 xref: EMBL:AAL26868.1 xref: EMBL:AAO26699.1 xref: EMBL:BAB71408.1 xref: EMBL:CAI19692.1 xref: EMBL:CAI40882.1 xref: EMBL:CAI40884.1 xref: EMBL:EAX03862.1 xref: UniProtKB:Q5JVR5 xref: UniProtKB:Q812C7 xref: UniProtKB:Q8TC65 xref: UniProtKB:Q96MA0 xref: UniProtKB:Q96PK8 xref: UniProtKB:Q96RN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012899 ! SLC26A8_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002594 ! sulfate transmembrane transporter activity relationship: has_function CCO:F0002805 ! anion exchanger activity relationship: has_function CCO:F0004141 ! oxalate transmembrane transporter activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0035938 name: SETD8_HUMAN def: "Histone-lysine N-methyltransferase SETD8" [UniProtKB:Q9NQR1] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9NQR1] synonym: "H4-K20-HMTase SETD8" EXACT [UniProtKB:Q9NQR1] synonym: "Lysine N-methyltransferase 5A" EXACT [UniProtKB:Q9NQR1] synonym: "PR-Set7" EXACT [UniProtKB:Q9NQR1] synonym: "PR/SET domain-containing protein 07" EXACT [UniProtKB:Q9NQR1] synonym: "PR/SET07" EXACT [UniProtKB:Q9NQR1] synonym: "SET domain-containing protein 8" EXACT [UniProtKB:Q9NQR1] xref: EMBL:AAF97812.2 xref: EMBL:AAH50346.1 xref: EMBL:AAL40879.1 xref: EMBL:AAM47033.1 xref: UniProtKB:Q86W83 xref: UniProtKB:Q8TD09 xref: UniProtKB:Q9NQR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010898 ! SETD8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0070386 ! SETD8_HUMAN-Phosphoserine100 [Term] id: CCO:B0035939 name: C8AP2_HUMAN def: "CASP8-associated protein 2" [UniProtKB:Q9UKL3] synonym: "FLICE-associated huge protein" EXACT [UniProtKB:Q9UKL3] xref: EMBL:AAD45157.1 xref: EMBL:AAD45537.2 xref: EMBL:AAF03367.1 xref: EMBL:AAH42577.1 xref: EMBL:AAH56685.1 xref: EMBL:BAA92067.1 xref: EMBL:BAA92553.2 xref: UniProtKB:Q6PH76 xref: UniProtKB:Q7LCQ7 xref: UniProtKB:Q86YD9 xref: UniProtKB:Q9NUQ4 xref: UniProtKB:Q9NZV9 xref: UniProtKB:Q9P2N1 xref: UniProtKB:Q9UKL3 xref: UniProtKB:Q9Y563 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0010892 ! CASP8AP2_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001425 ! death receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0003186 ! apoptotic protease activator activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: transforms_into CCO:B0035988 ! C8AP2_HUMAN-Phosphoserine1278 [Term] id: CCO:B0035951 name: THOP1_HUMAN def: "Thimet oligopeptidase" [UniProtKB:P52888] synonym: "EC 3.4.24.15" EXACT [UniProtKB:P52888] synonym: "Endopeptidase 24.15" EXACT [UniProtKB:P52888] synonym: "MP78" EXACT [UniProtKB:P52888] xref: EMBL:AAA82607.1 xref: EMBL:AAD13118.1 xref: EMBL:AAH00135.1 xref: EMBL:AAH02391.1 xref: EMBL:CAA90477.1 xref: UniProtKB:P52888 xref: UniProtKB:Q9UCB3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005084 ! THOP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006487 ! mphosph6-thop1 physical interaction relationship: transforms_into CCO:B0036035 ! THOP1_HUMAN-Phosphotyrosine278 [Term] id: CCO:B0035952 name: ACACA_HUMAN def: "Acetyl-CoA carboxylase 1" [UniProtKB:Q13085] synonym: "ACC-alpha" EXACT [UniProtKB:Q13085] synonym: "EC 6.4.1.2" EXACT [UniProtKB:Q13085] xref: EMBL:AAC50139.1 xref: EMBL:AAP69841.1 xref: EMBL:AAP94114.1 xref: EMBL:AAP94115.1 xref: EMBL:AAP94116.1 xref: EMBL:AAP94118.1 xref: EMBL:AAP94120.1 xref: EMBL:AAP94122.1 xref: EMBL:CAD59556.1 xref: EMBL:CAD59557.1 xref: EMBL:CAD92089.1 xref: UniProtKB:Q13085 xref: UniProtKB:Q6KEV6 xref: UniProtKB:Q6XDA8 xref: UniProtKB:Q7Z2G8 xref: UniProtKB:Q7Z561 xref: UniProtKB:Q7Z563 xref: UniProtKB:Q7Z564 xref: UniProtKB:Q86WB2 xref: UniProtKB:Q86WB3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004383 ! ACACA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007019 ! acaca-brca1-1 physical interaction relationship: participates_in CCO:I0007801 ! acaca-brca1 physical interaction relationship: participates_in CCO:I0018942 ! atxn1-acaca physical interaction relationship: transforms_into CCO:B0035968 ! ACACA_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0035969 ! ACACA_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0035970 ! ACACA_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0035971 ! ACACA_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0035972 ! ACACA_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0035973 ! ACACA_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0035974 ! ACACA_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0035975 ! ACACA_HUMAN-Phosphothreonine58 relationship: transforms_into CCO:B0035976 ! ACACA_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0035977 ! ACACA_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0035978 ! ACACA_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0035979 ! ACACA_HUMAN-Phosphothreonine1042 relationship: transforms_into CCO:B0035980 ! ACACA_HUMAN-Phosphoserine1201 relationship: transforms_into CCO:B0035981 ! ACACA_HUMAN-Phosphoserine1263 relationship: transforms_into CCO:B0035982 ! ACACA_HUMAN-Phosphoserine1844 relationship: transforms_into CCO:B0035983 ! ACACA_HUMAN-Phosphoserine2099 relationship: transforms_into CCO:B0035984 ! ACACA_HUMAN-Phosphotyrosine2108 relationship: transforms_into CCO:B0048153 ! ACACA_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0048154 ! ACACA_HUMAN-Phosphoserine488 [Term] id: CCO:B0035955 name: CXCL7_HUMAN def: "Platelet basic protein precursor" [UniProtKB:P02775] synonym: "C-X-C motif chemokine 7" EXACT [UniProtKB:P02775] synonym: "LDGF" EXACT [UniProtKB:P02775] synonym: "Leukocyte-derived growth factor" EXACT [UniProtKB:P02775] synonym: "Macrophage-derived growth factor" EXACT [UniProtKB:P02775] synonym: "MDGF" EXACT [UniProtKB:P02775] synonym: "PBP" EXACT [UniProtKB:P02775] synonym: "Small-inducible cytokine B7" EXACT [UniProtKB:P02775] xref: EMBL:AAA62836.1 xref: EMBL:AAH28217.1 xref: EMBL:AAK29642.1 xref: EMBL:AAY41004.1 xref: EMBL:CAG33086.1 xref: UniProtKB:P02775 xref: UniProtKB:Q6IBJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005575 ! PPBP_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001581 ! glucose transmembrane transporter activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:I0008376 ! cops7a-ppbp physical interaction relationship: participates_in CCO:I0008377 ! cox17-ppbp physical interaction relationship: participates_in CCO:I0008378 ! cugbp1-ppbp physical interaction relationship: participates_in CCO:I0008384 ! efna1-ppbp physical interaction relationship: participates_in CCO:I0008469 ! dmwd-ppbp physical interaction relationship: participates_in CCO:I0008489 ! pmaip1-ppbp physical interaction relationship: participates_in CCO:I0008503 ! scfd1-ppbp physical interaction relationship: participates_in CCO:I0008507 ! strn4-ppbp physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0035967 name: 2A5D_HUMAN-Phosphothreonine553 def: "Protein 2A5D_HUMAN with the residue 553 substituted with Phosphothreonine" [UniProtKB:Q14738] xref: UniProtKB:Q14738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005515 ! 2A5D_HUMAN [Term] id: CCO:B0035968 name: ACACA_HUMAN-Phosphoserine23 def: "Protein ACACA_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035969 name: ACACA_HUMAN-Phosphoserine25 def: "Protein ACACA_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035970 name: ACACA_HUMAN-Phosphoserine29 def: "Protein ACACA_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035971 name: ACACA_HUMAN-Phosphoserine48 def: "Protein ACACA_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035972 name: ACACA_HUMAN-Phosphoserine50 def: "Protein ACACA_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035973 name: ACACA_HUMAN-Phosphoserine53 def: "Protein ACACA_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035974 name: ACACA_HUMAN-Phosphoserine56 def: "Protein ACACA_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035975 name: ACACA_HUMAN-Phosphothreonine58 def: "Protein ACACA_HUMAN with the residue 58 substituted with Phosphothreonine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000474 ! acetyl-CoA carboxylase activity relationship: has_function CCO:F0000550 ! biotin carboxylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002381 ! biotin binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035976 name: ACACA_HUMAN-Phosphoserine60 def: "Protein ACACA_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035977 name: ACACA_HUMAN-Phosphoserine78 def: "Protein ACACA_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:Q13085] comment: By similarity xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035978 name: ACACA_HUMAN-Phosphoserine80 def: "Protein ACACA_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035979 name: ACACA_HUMAN-Phosphothreonine1042 def: "Protein ACACA_HUMAN with the residue 1042 substituted with Phosphothreonine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035980 name: ACACA_HUMAN-Phosphoserine1201 def: "Protein ACACA_HUMAN with the residue 1201 substituted with Phosphoserine" [UniProtKB:Q13085] comment: By similarity xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035981 name: ACACA_HUMAN-Phosphoserine1263 def: "Protein ACACA_HUMAN with the residue 1263 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035982 name: ACACA_HUMAN-Phosphoserine1844 def: "Protein ACACA_HUMAN with the residue 1844 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035983 name: ACACA_HUMAN-Phosphoserine2099 def: "Protein ACACA_HUMAN with the residue 2099 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035984 name: ACACA_HUMAN-Phosphotyrosine2108 def: "Protein ACACA_HUMAN with the residue 2108 substituted with Phosphotyrosine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0035985 name: ACVR1_HUMAN-Phosphoserine501 def: "Protein ACVR1_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q04771] xref: UniProtKB:Q04771 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003122 ! activin receptor activity, type I relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007318 ! follistatin binding relationship: has_function CCO:F0007319 ! activin binding relationship: has_function CCO:F0007780 ! transforming growth factor beta binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001896 ! apical part of cell relationship: located_in CCO:C0001980 ! activin receptor complex relationship: transformation_of CCO:B0001720 ! ACVR1_HUMAN [Term] id: CCO:B0035986 name: BPAEA_HUMAN-Phosphothreonine4352 def: "Protein BPAEA_HUMAN with the residue 4352 substituted with Phosphothreonine" [UniProtKB:O94833] xref: UniProtKB:O94833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001443 ! BPAEA_HUMAN [Term] id: CCO:B0035987 name: BUB1B_HUMAN-Phosphothreonine54 def: "Protein BUB1B_HUMAN with the residue 54 substituted with Phosphothreonine" [UniProtKB:O60566] xref: UniProtKB:O60566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000159 ! outer kinetochore of condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0002011 ! spindle midzone relationship: transformation_of CCO:B0001411 ! BUB1B_HUMAN [Term] id: CCO:B0035988 name: C8AP2_HUMAN-Phosphoserine1278 def: "Protein C8AP2_HUMAN with the residue 1278 substituted with Phosphoserine" [UniProtKB:Q9UKL3] xref: UniProtKB:Q9UKL3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035939 ! C8AP2_HUMAN [Term] id: CCO:B0035989 name: CAND1_HUMAN-Phosphothreonine624 def: "Protein CAND1_HUMAN with the residue 624 substituted with Phosphothreonine" [UniProtKB:Q86VP6] xref: UniProtKB:Q86VP6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:B0035990 name: CCNG2_HUMAN-Phosphoserine220 def: "Protein CCNG2_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q16589] xref: UniProtKB:Q16589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001821 ! CCNG2_HUMAN [Term] id: CCO:B0035991 name: CCNG2_HUMAN-Phosphoserine234 def: "Protein CCNG2_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q16589] xref: UniProtKB:Q16589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001821 ! CCNG2_HUMAN [Term] id: CCO:B0035992 name: CHD3_HUMAN-Phosphoserine43 def: "Protein CHD3_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0035993 name: CLAP2_HUMAN-Phosphoserine523 def: "Protein CLAP2_HUMAN with the residue 523 substituted with Phosphoserine" [UniProtKB:O75122] xref: UniProtKB:O75122 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:B0035994 name: CLIP1_HUMAN-Phosphothreonine822 def: "Protein CLIP1_HUMAN with the residue 822 substituted with Phosphothreonine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0035995 name: CNDD3_HUMAN-Phosphoserine1357 def: "Protein CNDD3_HUMAN with the residue 1357 substituted with Phosphoserine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0035996 name: CUL4A_HUMAN-Phosphotyrosine227 def: "Protein CUL4A_HUMAN with the residue 227 substituted with Phosphotyrosine" [UniProtKB:Q13619] xref: UniProtKB:Q13619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001762 ! CUL4A_HUMAN [Term] id: CCO:B0035997 name: DCC_HUMAN-Phosphoserine1073 def: "Protein DCC_HUMAN with the residue 1073 substituted with Phosphoserine" [UniProtKB:P43146] xref: UniProtKB:P43146 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001619 ! DCC_HUMAN [Term] id: CCO:B0035998 name: DCC_HUMAN-Phosphothreonine1074 def: "Protein DCC_HUMAN with the residue 1074 substituted with Phosphothreonine" [UniProtKB:P43146] xref: UniProtKB:P43146 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001363 ! netrin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001004 ! axon relationship: transformation_of CCO:B0001619 ! DCC_HUMAN [Term] id: CCO:B0036000 name: EID1_HUMAN-Phosphoserine2 def: "Protein EID1_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q9Y6B2] xref: UniProtKB:Q9Y6B2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002263 ! EID1_HUMAN [Term] id: CCO:B0036001 name: EID1_HUMAN-Phosphoserine8 def: "Protein EID1_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q9Y6B2] xref: UniProtKB:Q9Y6B2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002263 ! EID1_HUMAN [Term] id: CCO:B0036002 name: ERCC3_HUMAN-Phosphoserine370 def: "Protein ERCC3_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:P19447] xref: UniProtKB:P19447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028502 ! ERCC3_HUMAN [Term] id: CCO:B0036003 name: ESR1_HUMAN-Phosphothreonine7 def: "Protein ESR1_HUMAN with the residue 7 substituted with Phosphothreonine" [UniProtKB:P03372] xref: UniProtKB:P03372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:B0036004 name: ESR1_HUMAN-Phosphoserine10 def: "Protein ESR1_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P03372] xref: UniProtKB:P03372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:B0036005 name: FOXO4_HUMAN-Phosphoserine111 def: "Protein FOXO4_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:P98177] xref: UniProtKB:P98177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001706 ! FOXO4_HUMAN [Term] id: CCO:B0036006 name: FOXO4_HUMAN-Phosphoserine200 def: "Protein FOXO4_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:P98177] xref: UniProtKB:P98177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001706 ! FOXO4_HUMAN [Term] id: CCO:B0036007 name: FZR_HUMAN-Phosphotyrosine91 def: "Protein FZR_HUMAN with the residue 91 substituted with Phosphotyrosine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0036008 name: FZR_HUMAN-Phosphoserine92 def: "Protein FZR_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0036009 name: ILKAP_HUMAN-Phosphothreonine81 def: "Protein ILKAP_HUMAN with the residue 81 substituted with Phosphothreonine" [UniProtKB:Q9H0C8] xref: UniProtKB:Q9H0C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002123 ! ILKAP_HUMAN [Term] id: CCO:B0036010 name: KI67_HUMAN-Phosphoserine352 def: "Protein KI67_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0036011 name: M3K1_HUMAN-Phosphothreonine657 def: "Protein M3K1_HUMAN with the residue 657 substituted with Phosphothreonine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0036012 name: M3K1_HUMAN-Phosphothreonine665 def: "Protein M3K1_HUMAN with the residue 665 substituted with Phosphothreonine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0036013 name: MEN1_HUMAN-Phosphoserine399 def: "Protein MEN1_HUMAN with the residue 399 substituted with Phosphoserine" [UniProtKB:O00255] xref: UniProtKB:O00255 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000082 ! four-way junction DNA binding relationship: has_function CCO:F0000085 ! Y-form DNA binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0001403 ! cleavage furrow relationship: located_in CCO:C0001616 ! histone methyltransferase complex relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:B0036014 name: MLH3_HUMAN-Phosphothreonine606 def: "Protein MLH3_HUMAN with the residue 606 substituted with Phosphothreonine" [UniProtKB:Q9UHC1] xref: UniProtKB:Q9UHC1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002200 ! MLH3_HUMAN [Term] id: CCO:B0036015 name: MLH3_HUMAN-Phosphothreonine610 def: "Protein MLH3_HUMAN with the residue 610 substituted with Phosphothreonine" [UniProtKB:Q9UHC1] xref: UniProtKB:Q9UHC1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002200 ! MLH3_HUMAN [Term] id: CCO:B0036016 name: MLTK_HUMAN-Phosphoserine633 def: "Protein MLTK_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0036017 name: MYH10_HUMAN-Phosphothreonine1376 def: "Protein MYH10_HUMAN with the residue 1376 substituted with Phosphothreonine" [UniProtKB:P35580] xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0036018 name: NCOR2_HUMAN-Phosphoserine956 def: "Protein NCOR2_HUMAN with the residue 956 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0036019 name: NIPA_HUMAN-Phosphothreonine84 def: "Protein NIPA_HUMAN with the residue 84 substituted with Phosphothreonine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0036020 name: PDCD4_HUMAN-Phosphoserine94 def: "Protein PDCD4_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q53EL6] xref: UniProtKB:Q53EL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001836 ! PDCD4_HUMAN [Term] id: CCO:B0036021 name: PDS5B_HUMAN-Phosphoserine1379 def: "Protein PDS5B_HUMAN with the residue 1379 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0036022 name: PR15A_HUMAN-Phosphotyrosine262 def: "Protein PR15A_HUMAN with the residue 262 substituted with Phosphotyrosine" [UniProtKB:O75807] xref: UniProtKB:O75807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: transformation_of CCO:B0001436 ! PR15A_HUMAN [Term] id: CCO:B0036023 name: PR15A_HUMAN-Phosphoserine264 def: "Protein PR15A_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:O75807] xref: UniProtKB:O75807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001436 ! PR15A_HUMAN [Term] id: CCO:B0036024 name: PTN6_HUMAN-Phosphotyrosine509 def: "Protein PTN6_HUMAN with the residue 509 substituted with Phosphotyrosine" [UniProtKB:P29350] xref: UniProtKB:P29350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005608 ! PTN6_HUMAN [Term] id: CCO:B0036025 name: RANB3_HUMAN-Phosphoserine333 def: "Protein RANB3_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0036026 name: RBL2_HUMAN-Phosphothreonine1019 def: "Protein RBL2_HUMAN with the residue 1019 substituted with Phosphothreonine" [UniProtKB:Q08999] xref: UniProtKB:Q08999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001725 ! RBL2_HUMAN [Term] id: CCO:B0036027 name: REN3A_HUMAN-Phosphoserine68 def: "Protein REN3A_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:Q9H1J1] xref: UniProtKB:Q9H1J1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005436 ! REN3A_HUMAN [Term] id: CCO:B0036028 name: RL21_HUMAN-Phosphothreonine47 def: "Protein RL21_HUMAN with the residue 47 substituted with Phosphothreonine" [UniProtKB:P46778] xref: UniProtKB:P46778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0005862 ! RL21_HUMAN [Term] id: CCO:B0036029 name: RLA2_HUMAN-Phosphoserine16 def: "Protein RLA2_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:P05387] xref: UniProtKB:P05387 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:B0036030 name: RS13_HUMAN-Phosphoserine30 def: "Protein RS13_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:P62277] xref: UniProtKB:P62277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005748 ! RS13_HUMAN [Term] id: CCO:B0036031 name: SMRC2_HUMAN-Phosphoserine806 def: "Protein SMRC2_HUMAN with the residue 806 substituted with Phosphoserine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0036032 name: STA5A_HUMAN-Phosphothreonine372 def: "Protein STA5A_HUMAN with the residue 372 substituted with Phosphothreonine" [UniProtKB:P42229] xref: UniProtKB:P42229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001609 ! STA5A_HUMAN [Term] id: CCO:B0036033 name: STA5A_HUMAN-Phosphoserine375 def: "Protein STA5A_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:P42229] xref: UniProtKB:P42229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001609 ! STA5A_HUMAN [Term] id: CCO:B0036034 name: TFDP1_HUMAN-Phosphoserine183 def: "Protein TFDP1_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q14186] xref: UniProtKB:Q14186 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001776 ! TFDP1_HUMAN [Term] id: CCO:B0036035 name: THOP1_HUMAN-Phosphotyrosine278 def: "Protein THOP1_HUMAN with the residue 278 substituted with Phosphotyrosine" [UniProtKB:P52888] comment: By similarity xref: UniProtKB:P52888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0035951 ! THOP1_HUMAN [Term] id: CCO:B0036036 name: TITIN_HUMAN-Phosphoserine4065 def: "Protein TITIN_HUMAN with the residue 4065 substituted with Phosphoserine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0036037 name: TITIN_HUMAN-Phosphoserine4068 def: "Protein TITIN_HUMAN with the residue 4068 substituted with Phosphoserine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0036038 name: TLE3_HUMAN-Phosphoserine205 def: "Protein TLE3_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0036039 name: TLE3_HUMAN-Phosphoserine292 def: "Protein TLE3_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0036040 name: WAPL_HUMAN-Phosphoserine223 def: "Protein WAPL_HUMAN with the residue 223 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0036047 name: PEPD_HUMAN def: "Xaa-Pro dipeptidase" [UniProtKB:P12955] synonym: "EC 3.4.13.9" EXACT [UniProtKB:P12955] synonym: "Imidodipeptidase" EXACT [UniProtKB:P12955] synonym: "Peptidase D" EXACT [UniProtKB:P12955] synonym: "Prolidase" EXACT [UniProtKB:P12955] synonym: "Proline dipeptidase" EXACT [UniProtKB:P12955] synonym: "X-Pro dipeptidase" EXACT [UniProtKB:P12955] xref: EMBL:AAA60064.1 xref: EMBL:AAH04305.1 xref: EMBL:AAH15027.1 xref: EMBL:AAH28295.1 xref: EMBL:AAP35338.1 xref: UniProtKB:P12955 xref: UniProtKB:Q8TBN9 xref: UniProtKB:Q9BT75 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011599 ! PEPD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019054 ! atxn1-pepd physical interaction relationship: transforms_into CCO:B0039578 ! PEPD_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0039579 ! PEPD_HUMAN-Phosphothreonine188 relationship: transforms_into CCO:B0039580 ! PEPD_HUMAN-Phosphothreonine487 [Term] id: CCO:B0036109 name: CO3_HUMAN def: "Complement C3 precursor" [UniProtKB:P01024] synonym: "C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1" EXACT [UniProtKB:P01024] xref: EMBL:AAA85332.1 xref: EMBL:AAR89906.1 xref: UniProtKB:P01024 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011306 ! C3_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0018217 ! z39ig-c3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis relationship: transforms_into CCO:B0039359 ! CO3_HUMAN-Phosphotyrosine489 [Term] id: CCO:B0036139 name: SENP2_HUMAN def: "Sentrin-specific protease 2" [UniProtKB:Q9HC62] synonym: "Axam2" EXACT [UniProtKB:Q9HC62] synonym: "EC 3.4.22.-" EXACT [UniProtKB:Q9HC62] synonym: "Sentrin/SUMO-specific protease SENP2" EXACT [UniProtKB:Q9HC62] synonym: "SMT3-specific isopeptidase 2" EXACT [UniProtKB:Q9HC62] synonym: "Smt3ip2" EXACT [UniProtKB:Q9HC62] xref: EMBL:AAG15309.2 xref: EMBL:AAH40609.1 xref: EMBL:BAA92569.2 xref: EMBL:BAB55222.1 xref: EMBL:CAD39043.1 xref: UniProtKB:Q8IW97 xref: UniProtKB:Q96SR2 xref: UniProtKB:Q9HC62 xref: UniProtKB:Q9P2L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011676 ! SENP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003473 ! SUMO-specific protease activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0018255 ! senp2-sumo1-1 direct interaction relationship: participates_in CCO:I0019945 ! cdk5rap2-senp2 physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: transforms_into CCO:B0039648 ! SENP2_HUMAN-Phosphotyrosine216 [Term] id: CCO:B0036172 name: GSTO1_HUMAN def: "Glutathione S-transferase omega-1" [UniProtKB:P78417] synonym: "EC 2.5.1.18" EXACT [UniProtKB:P78417] synonym: "GSTO 1-1" EXACT [UniProtKB:P78417] xref: EMBL:AAB70109.1 xref: EMBL:AAF73376.1 xref: EMBL:AAH00127.1 xref: EMBL:AAV68046.1 xref: EMBL:CAD97673.1 xref: EMBL:CAI17224.1 xref: UniProtKB:P78417 xref: UniProtKB:Q5TA03 xref: UniProtKB:Q7Z3T2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011448 ! GSTO1_human relationship: has_function CCO:F0000783 ! glutathione transferase activity relationship: has_function CCO:F0003254 ! monodehydroascorbate reductase (NADH) activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019727 ! gsto1-htatip physical interaction relationship: participates_in CCO:I0019728 ! gsto1-setdb1 physical interaction [Term] id: CCO:B0036188 name: TCTP_HUMAN def: "Translationally-controlled tumor protein" [UniProtKB:P13693] synonym: "Fortilin" EXACT [UniProtKB:P13693] synonym: "Histamine-releasing factor" EXACT [UniProtKB:P13693] synonym: "HRF" EXACT [UniProtKB:P13693] synonym: "p23" EXACT [UniProtKB:P13693] synonym: "TCTP" EXACT [UniProtKB:P13693] xref: EMBL:AAH03352.1 xref: EMBL:AAH12431.1 xref: EMBL:AAH52333.1 xref: EMBL:AAM51565.1 xref: EMBL:AAQ01550.1 xref: EMBL:CAA34200.1 xref: EMBL:CAB87812.1 xref: EMBL:CAG33317.1 xref: EMBL:CAH72034.1 xref: UniProtKB:P13693 xref: UniProtKB:Q6YLS2 xref: UniProtKB:Q7Z4J4 xref: UniProtKB:Q96EE2 xref: UniProtKB:Q9UC70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011706 ! TPT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0039671 ! TCTP_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0039672 ! TCTP_HUMAN-Phosphoserine64 [Term] id: CCO:B0036272 name: ANM6_HUMAN def: "Protein arginine N-methyltransferase 6" [UniProtKB:Q96LA8] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q96LA8] synonym: "Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6" EXACT [UniProtKB:Q96LA8] xref: EMBL:AAH02729.3 xref: EMBL:AAH73866.1 xref: EMBL:AAK85733.1 xref: EMBL:BAA91681.1 xref: EMBL:CAI19090.1 xref: EMBL:EAW51248.1 xref: UniProtKB:Q5T5Y5 xref: UniProtKB:Q6DKI4 xref: UniProtKB:Q96LA8 xref: UniProtKB:Q9NVR8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011243 ! PRMT6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008768 ! hrmt1l6-hmg2a physical interaction relationship: participates_in CCO:I0008770 ! hrmt1l6-hmga2 physical interaction [Term] id: CCO:B0036287 name: HILS1_HUMAN def: "Spermatid-specific linker histone H1-like protein" [UniProtKB:P60008] xref: EMBL:AAQ23050.1 xref: UniProtKB:P60008 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011459 ! HILS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0039454 ! HILS1_HUMAN-Phosphothreonine130 [Term] id: CCO:B0036431 name: SPHK2_HUMAN def: "Sphingosine kinase 2" [UniProtKB:Q9NRA0] synonym: "EC 2.7.1.91" EXACT [UniProtKB:Q9NRA0] synonym: "SK 2" EXACT [UniProtKB:Q9NRA0] synonym: "SPK 2" EXACT [UniProtKB:Q9NRA0] xref: EMBL:AAF74124.1 xref: EMBL:AAH06161.1 xref: EMBL:AAH10671.1 xref: EMBL:BAA91280.1 xref: EMBL:CAB66636.1 xref: UniProtKB:Q9BRN1 xref: UniProtKB:Q9H0Q2 xref: UniProtKB:Q9NRA0 xref: UniProtKB:Q9NWU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011684 ! SPHK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018695 ! sphk2-fyn-1 direct interaction relationship: participates_in CCO:I0018696 ! sphk2-lyn-1 direct interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0039654 ! SPHK2_HUMAN-Phosphoserine399 [Term] id: CCO:B0036434 name: A0T4C8_HUMAN def: "Sphingosine kinase-2 variant" [UniProtKB:A0T4C8] xref: EMBL:ABK81123.1 xref: UniProtKB:A0T4C8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011684 ! SPHK2_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0036469 name: HCFC2_HUMAN def: "Host cell factor 2" [UniProtKB:Q9Y5Z7] synonym: "C2 factor" EXACT [UniProtKB:Q9Y5Z7] synonym: "HCF-2" EXACT [UniProtKB:Q9Y5Z7] xref: EMBL:AAD27814.1 xref: EMBL:AAH33799.1 xref: UniProtKB:Q9Y5Z7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011455 ! HCFC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006305 ! mll-hcfc2-2 physical interaction relationship: participates_in CCO:I0008569 ! mll-hcfc2-1 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0048274 ! HCFC2_HUMAN-Phosphotyrosine159 [Term] id: CCO:B0036514 name: ST17A_HUMAN def: "Serine/threonine-protein kinase 17A" [UniProtKB:Q9UEE5] synonym: "DAP kinase-related apoptosis-inducing protein kinase 1" EXACT [UniProtKB:Q9UEE5] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UEE5] xref: EMBL:AAH23508.2 xref: EMBL:AAH47696.1 xref: EMBL:BAA34126.1 xref: UniProtKB:Q8IVC8 xref: UniProtKB:Q9UEE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011686 ! STK17A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0070944 ! ST17A_HUMAN-Phosphoserine28 [Term] id: CCO:B0036515 name: Q14CQ7_HUMAN xref: UniProtKB:Q14CQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0036523 name: ST17B_HUMAN def: "Serine/threonine-protein kinase 17B" [UniProtKB:O94768] synonym: "DAP kinase-related apoptosis-inducing protein kinase 2" EXACT [UniProtKB:O94768] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O94768] xref: EMBL:AAH16040.1 xref: EMBL:BAA34127.1 xref: UniProtKB:O94768 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011687 ! STK17B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0036525 name: DAPK2_HUMAN def: "Death-associated protein kinase 2" [UniProtKB:Q9UIK4] synonym: "DAP kinase 2" EXACT [UniProtKB:Q9UIK4] synonym: "DAP-kinase-related protein 1" EXACT [UniProtKB:Q9UIK4] synonym: "DRP-1" EXACT [UniProtKB:Q9UIK4] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9UIK4] xref: EMBL:AAC35001.1 xref: EMBL:AAI14507.1 xref: EMBL:BAA88063.1 xref: UniProtKB:O75892 xref: UniProtKB:Q24JS1 xref: UniProtKB:Q9UIK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011340 ! DAPK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019493 ! dapk2-dapk2-4 physical interaction relationship: participates_in CCO:I0019507 ! dapk2-dapk2-1 physical interaction relationship: participates_in CCO:I0019508 ! dapk2-dapk2-2 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0039378 ! DAPK2_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0039379 ! DAPK2_HUMAN-Phosphoserine349 [Term] id: CCO:B0036526 name: MYLK2_HUMAN def: "Myosin light chain kinase 2, skeletal/cardiac muscle" [UniProtKB:Q9H1R3] synonym: "EC 2.7.11.18" EXACT [UniProtKB:Q9H1R3] synonym: "MLCK2" EXACT [UniProtKB:Q9H1R3] xref: EMBL:AAH07753.1 xref: EMBL:AAH69627.1 xref: EMBL:AAH92413.1 xref: EMBL:AAI27623.1 xref: EMBL:AAK15494.1 xref: EMBL:CAC10006.1 xref: EMBL:CAC81354.1 xref: UniProtKB:Q569L1 xref: UniProtKB:Q96I84 xref: UniProtKB:Q9H1R3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011548 ! MYLK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001055 ! myosin light chain kinase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004926 ! myosin light chain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000933 ! sarcomere relationship: participates_in CCO:I0016656 ! map3k1-mylk2 physical interaction relationship: participates_in CCO:I0016771 ! map3k3-mylk2 physical interaction relationship: participates_in CCO:I0017056 ! tnfrsf1b-mylk2 physical interaction relationship: participates_in CCO:I0017132 ! traf2-mylk2 physical interaction relationship: participates_in CCO:P0001745 ! regulation of muscle filament sliding relationship: transforms_into CCO:B0039538 ! MYLK2_HUMAN-N-acetylalanine2 [Term] id: CCO:B0036527 name: Q5T8F1_HUMAN def: "Death-associated protein kinase 1" [UniProtKB:Q5T8F1] xref: EMBL:CAH71696.1 xref: EMBL:CAH73544.1 xref: EMBL:CAI16306.1 xref: UniProtKB:Q5T8F1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004435 ! DAPK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0036528 name: MYLK_HUMAN def: "Myosin light chain kinase, smooth muscle" [UniProtKB:Q15746] synonym: "EC 2.7.11.18" EXACT [UniProtKB:Q15746] synonym: "Kinase-related protein" EXACT [UniProtKB:Q15746] synonym: "KRP" EXACT [UniProtKB:Q15746] synonym: "MLCK" EXACT [UniProtKB:Q15746] synonym: "Telokin" EXACT [UniProtKB:Q15746] xref: EMBL:AAC18423.2 xref: EMBL:AAD15921.2 xref: EMBL:AAD15922.1 xref: EMBL:AAD15923.1 xref: EMBL:AAD15924.1 xref: EMBL:AAD51380.1 xref: EMBL:AAD51381.1 xref: EMBL:AAD54018.1 xref: EMBL:AAQ02673.1 xref: EMBL:AAR29061.1 xref: EMBL:AAR29062.1 xref: EMBL:BAB21504.1 xref: EMBL:CAA59685.1 xref: EMBL:CAA62378.1 xref: UniProtKB:O95796 xref: UniProtKB:O95797 xref: UniProtKB:O95798 xref: UniProtKB:O95799 xref: UniProtKB:Q14844 xref: UniProtKB:Q15746 xref: UniProtKB:Q16794 xref: UniProtKB:Q5MY99 xref: UniProtKB:Q5MYA0 xref: UniProtKB:Q7Z4J0 xref: UniProtKB:Q9C0L5 xref: UniProtKB:Q9UBG5 xref: UniProtKB:Q9UIT9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011550 ! MYLK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: transforms_into CCO:B0039539 ! MYLK_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0039540 ! MYLK_HUMAN-Phosphotyrosine464 relationship: transforms_into CCO:B0039541 ! MYLK_HUMAN-Phosphotyrosine471 relationship: transforms_into CCO:B0039542 ! MYLK_HUMAN-Phosphoserine814 relationship: transforms_into CCO:B0039543 ! MYLK_HUMAN-Phosphoserine1759 relationship: transforms_into CCO:B0039544 ! MYLK_HUMAN-Phosphoserine1776 relationship: transforms_into CCO:B0068382 ! MYLK_HUMAN-Phosphoserine1438 relationship: transforms_into CCO:B0068383 ! MYLK_HUMAN-Phosphoserine1760 relationship: transforms_into CCO:B0068384 ! MYLK_HUMAN-Phosphoserine1772 relationship: transforms_into CCO:B0068385 ! MYLK_HUMAN-Phosphothreonine1774 relationship: transforms_into CCO:B0068386 ! MYLK_HUMAN-Phosphothreonine1778 relationship: transforms_into CCO:B0068387 ! MYLK_HUMAN-Phosphoserine1779 [Term] id: CCO:B0036567 name: IF5A1_HUMAN def: "Eukaryotic translation initiation factor 5A-1" [UniProtKB:P63241] synonym: "eIF-4D" EXACT [UniProtKB:P63241] synonym: "eIF-5A" EXACT [UniProtKB:P63241] synonym: "eIF-5A-1" EXACT [UniProtKB:P63241] synonym: "eIF-5A1" EXACT [UniProtKB:P63241] synonym: "Eukaryotic initiation factor 5A isoform 1" EXACT [UniProtKB:P63241] synonym: "Rev-binding factor" EXACT [UniProtKB:P63241] xref: EMBL:AAA58453.1 xref: EMBL:AAA86989.1 xref: EMBL:AAD14095.1 xref: EMBL:AAH00751.1 xref: EMBL:AAH01832.1 xref: EMBL:AAH30160.1 xref: EMBL:AAH80196.1 xref: EMBL:AAH85015.1 xref: EMBL:AAI07780.1 xref: EMBL:AAN17514.1 xref: EMBL:AAN17515.1 xref: EMBL:AAN17516.1 xref: EMBL:AAN17518.1 xref: UniProtKB:P10159 xref: UniProtKB:P63241 xref: UniProtKB:Q16182 xref: UniProtKB:Q7L7L3 xref: UniProtKB:Q7Z4L1 xref: UniProtKB:Q9D0G2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011483 ! EIF5A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002631 ! positive regulation of translational initiation relationship: transforms_into CCO:B0039463 ! IF5A1_HUMAN-Blocked amino end (Ala)2 relationship: transforms_into CCO:B0039464 ! IF5A1_HUMAN-Hypusine50 relationship: transforms_into CCO:B0039465 ! IF5A1_HUMAN-N6-acetyllysine68 [Term] id: CCO:B0036577 name: IF5A2_HUMAN def: "Eukaryotic translation initiation factor 5A-2" [UniProtKB:Q9GZV4] synonym: "eIF-5A-2" EXACT [UniProtKB:Q9GZV4] synonym: "eIF-5A2" EXACT [UniProtKB:Q9GZV4] synonym: "Eukaryotic initiation factor 5A isoform 2" EXACT [UniProtKB:Q9GZV4] xref: EMBL:AAF98810.1 xref: EMBL:AAG23176.1 xref: EMBL:AAH36072.1 xref: EMBL:AAO18676.1 xref: EMBL:AAO18677.1 xref: EMBL:AAO18678.1 xref: EMBL:AAO18679.1 xref: UniProtKB:Q9GZV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011484 ! EIF5A2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015380 ! dhps-eif5a2 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0039466 ! IF5A2_HUMAN-Blocked amino end (Ala)2 relationship: transforms_into CCO:B0039467 ! IF5A2_HUMAN-Hypusine50 relationship: transforms_into CCO:B0039468 ! IF5A2_HUMAN-N6-acetyllysine68 [Term] id: CCO:B0036594 name: NKG2C_HUMAN def: "NKG2-C type II integral membrane protein" [UniProtKB:P26717] synonym: "CD159 antigen-like family member C" EXACT [UniProtKB:P26717] synonym: "CD159c antigen" EXACT [UniProtKB:P26717] synonym: "NK cell receptor C" EXACT [UniProtKB:P26717] synonym: "NKG2-C-activating NK receptor" EXACT [UniProtKB:P26717] xref: EMBL:AAF86972.1 xref: EMBL:AAH93644.1 xref: EMBL:AAI12040.1 xref: EMBL:CAA04922.1 xref: EMBL:CAA38651.1 xref: EMBL:CAA73498.1 xref: UniProtKB:O43802 xref: UniProtKB:P26717 xref: UniProtKB:Q52M74 xref: UniProtKB:Q9NR42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011562 ! KLRC2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0036600 name: NKG2A_HUMAN def: "NKG2-A/NKG2-B type II integral membrane protein" [UniProtKB:P26715] synonym: "CD159 antigen-like family member A" EXACT [UniProtKB:P26715] synonym: "CD159a antigen" EXACT [UniProtKB:P26715] synonym: "NK cell receptor A" EXACT [UniProtKB:P26715] synonym: "NKG2-A/B-activating NK receptor" EXACT [UniProtKB:P26715] xref: EMBL:AAB17133.1 xref: EMBL:AAC17488.1 xref: EMBL:AAH12550.1 xref: EMBL:AAH53840.1 xref: EMBL:AAL65234.1 xref: EMBL:CAA38649.1 xref: EMBL:CAA38650.1 xref: UniProtKB:P26715 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011561 ! KLRC1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0036609 name: MAST1_HUMAN def: "Microtubule-associated serine/threonine-protein kinase 1" [UniProtKB:Q9Y2H9] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y2H9] synonym: "Syntrophin-associated serine/threonine-protein kinase" EXACT [UniProtKB:Q9Y2H9] xref: EMBL:AAB51171.1 xref: EMBL:AAH27985.1 xref: EMBL:BAA76817.1 xref: UniProtKB:O00114 xref: UniProtKB:Q8N6X0 xref: UniProtKB:Q9Y2H9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011528 ! MAST1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0039518 ! MAST1_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0039519 ! MAST1_HUMAN-Phosphoserine163 [Term] id: CCO:B0036627 name: RFC2_HUMAN def: "Replication factor C subunit 2" [UniProtKB:P35250] synonym: "A1 40 kDa subunit" EXACT [UniProtKB:P35250] synonym: "Activator 1 40 kDa subunit" EXACT [UniProtKB:P35250] synonym: "Activator 1 subunit 2" EXACT [UniProtKB:P35250] synonym: "Replication factor C 40 kDa subunit" EXACT [UniProtKB:P35250] synonym: "RF-C 40 kDa subunit" EXACT [UniProtKB:P35250] synonym: "RFC40" EXACT [UniProtKB:P35250] xref: EMBL:AAB09786.1 xref: EMBL:AAC04860.1 xref: EMBL:AAH02813.1 xref: EMBL:AAL82503.1 xref: EMBL:AAP22334.1 xref: UniProtKB:P32846 xref: UniProtKB:P35250 xref: UniProtKB:Q9BU93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011651 ! RFC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000281 ! DNA clamp loader activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000268 ! DNA replication factor C complex relationship: participates_in CCO:I0015869 ! rfc1-rfc2-2 physical interaction relationship: participates_in CCO:I0015870 ! rfc1-rfc2-3 physical interaction relationship: participates_in CCO:I0015871 ! rfc1-rfc2-4 physical interaction relationship: participates_in CCO:I0015872 ! rfc2-rfc3-1 physical interaction relationship: participates_in CCO:I0015873 ! rfc2-rfc4-4 physical interaction relationship: participates_in CCO:I0015875 ! rfc1-rfc3-1 physical interaction relationship: participates_in CCO:I0015878 ! rfc2-rfc4-5 physical interaction relationship: participates_in CCO:I0015904 ! rfc2-prkar1a-1 physical interaction relationship: participates_in CCO:I0015905 ! rfc2-prkar1a-2 physical interaction relationship: participates_in CCO:I0015906 ! prkar1a-rfc2-1 physical interaction relationship: participates_in CCO:I0015907 ! rfc1-rfc2-1 physical interaction relationship: participates_in CCO:I0015908 ! rfc2-rfc4-1 physical interaction relationship: participates_in CCO:I0017805 ! rfc2-rfc3-3 physical interaction relationship: participates_in CCO:I0018602 ! rfc2-prkar1a-4 physical interaction relationship: participates_in CCO:I0018603 ! rfc2-prkar1a-5 physical interaction relationship: participates_in CCO:I0018604 ! rfc2-prkar1a-6 physical interaction relationship: participates_in CCO:I0018606 ! rfc2-rfc4-2 physical interaction relationship: participates_in CCO:I0018607 ! rfc2-rfc4-3 physical interaction relationship: participates_in CCO:I0019241 ! rfc2-prkar1a-3 physical interaction relationship: participates_in CCO:I0019330 ! rfc_human physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0036631 name: LRRN2_HUMAN def: "Leucine-rich repeat neuronal protein 2 precursor" [UniProtKB:O75325] synonym: "Glioma amplified on chromosome 1 protein" EXACT [UniProtKB:O75325] synonym: "Leucine-rich repeat neuronal protein 5" EXACT [UniProtKB:O75325] xref: EMBL:AAC39792.1 xref: EMBL:AAH34047.1 xref: EMBL:AAH68541.1 xref: EMBL:AAQ88657.1 xref: EMBL:CAI14096.1 xref: UniProtKB:O75325 xref: UniProtKB:Q5T0Y0 xref: UniProtKB:Q6UXM0 xref: UniProtKB:Q8N182 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011517 ! LRRN2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0036665 name: Q1M183_HUMAN def: "HMGA2e" [UniProtKB:Q1M183] synonym: "HMGA2e'" EXACT [UniProtKB:Q1M183] xref: EMBL:AAU43855.1 xref: EMBL:AAU43856.1 xref: UniProtKB:Q1M183 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011851 ! HMGA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0036788 name: GBX2_HUMAN def: "Homeobox protein GBX-2" [UniProtKB:P52951] synonym: "Gastrulation and brain-specific homeobox protein 2" EXACT [UniProtKB:P52951] xref: EMBL:AAA17406.1 xref: EMBL:AAC03241.1 xref: EMBL:AAD39907.1 xref: EMBL:AAX93240.1 xref: UniProtKB:O43833 xref: UniProtKB:P52951 xref: UniProtKB:Q53RX5 xref: UniProtKB:Q9Y5Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011435 ! GBX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036789 name: HXB8_HUMAN def: "Homeobox protein Hox-B8" [UniProtKB:P17481] synonym: "Hox-2.4" EXACT [UniProtKB:P17481] synonym: "Hox-2D" EXACT [UniProtKB:P17481] xref: EMBL:AAG42143.1 xref: EMBL:CAA34295.1 xref: UniProtKB:P17481 xref: UniProtKB:Q9H1I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011472 ! HOXB8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036790 name: HXB5_HUMAN def: "Homeobox protein Hox-B5" [UniProtKB:P09067] synonym: "HHO.C10" EXACT [UniProtKB:P09067] synonym: "Hox-2A" EXACT [UniProtKB:P09067] synonym: "HU-1" EXACT [UniProtKB:P09067] xref: EMBL:AAA52681.1 xref: EMBL:AAA52682.1 xref: EMBL:AAB59430.1 xref: EMBL:AAG31553.1 xref: EMBL:AAI17248.1 xref: EMBL:CAA27420.1 xref: UniProtKB:P09067 xref: UniProtKB:P09069 xref: UniProtKB:Q17RP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011469 ! HOXB5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036792 name: HXD4_HUMAN def: "Homeobox protein Hox-D4" [UniProtKB:P09016] synonym: "HHO.C13" EXACT [UniProtKB:P09016] synonym: "Hox-4B" EXACT [UniProtKB:P09016] synonym: "Hox-5.1" EXACT [UniProtKB:P09016] xref: EMBL:AAH16763.1 xref: EMBL:AAH74797.1 xref: EMBL:CAA28411.1 xref: EMBL:CAA35237.1 xref: UniProtKB:P09016 xref: UniProtKB:Q96AU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011478 ! HOXD4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036793 name: HXA7_HUMAN def: "Homeobox protein Hox-A7" [UniProtKB:P31268] synonym: "Hox 1.1" EXACT [UniProtKB:P31268] synonym: "Hox-1A" EXACT [UniProtKB:P31268] xref: EMBL:AAB94604.1 xref: EMBL:AAD00727.1 xref: EMBL:AAD01939.2 xref: EMBL:CAA06713.1 xref: EMBL:CAA59270.1 xref: UniProtKB:O43368 xref: UniProtKB:O43486 xref: UniProtKB:O95655 xref: UniProtKB:P31268 xref: UniProtKB:Q9NSC8 xref: UniProtKB:Q9UDM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011467 ! HOXA7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002431 ! negative regulation of keratinocyte differentiation [Term] id: CCO:B0036796 name: GBX1_HUMAN def: "Homeobox protein GBX-1" [UniProtKB:Q14549] synonym: "Gastrulation and brain-specific homeobox protein 1" EXACT [UniProtKB:Q14549] xref: EMBL:AAA36002.1 xref: UniProtKB:Q14549 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011434 ! GBX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036797 name: HXB4_HUMAN def: "Homeobox protein Hox-B4" [UniProtKB:P17483] synonym: "Hox-2.6" EXACT [UniProtKB:P17483] synonym: "Hox-2F" EXACT [UniProtKB:P17483] xref: EMBL:AAG31554.1 xref: EMBL:AAG45052.1 xref: EMBL:AAH49204.1 xref: EMBL:CAA34296.1 xref: EMBL:CAB70742.1 xref: UniProtKB:P17483 xref: UniProtKB:Q9NTA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011468 ! HOXB4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002772 ! somatic stem cell division [Term] id: CCO:B0036799 name: HXB7_HUMAN def: "Homeobox protein Hox-B7" [UniProtKB:P09629] synonym: "HHO.C1" EXACT [UniProtKB:P09629] synonym: "Hox-2C" EXACT [UniProtKB:P09629] xref: EMBL:AAA36003.1 xref: EMBL:AAA36005.1 xref: EMBL:AAB19469.2 xref: UniProtKB:P09629 xref: UniProtKB:Q15957 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011471 ! HOXB7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036801 name: HXA5_HUMAN def: "Homeobox protein Hox-A5" [UniProtKB:P20719] synonym: "Hox-1C" EXACT [UniProtKB:P20719] xref: EMBL:AAA58663.1 xref: EMBL:AAH13682.1 xref: EMBL:AAP88746.1 xref: EMBL:CAG47052.1 xref: UniProtKB:O43367 xref: UniProtKB:P20719 xref: UniProtKB:Q96CY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011465 ! HOXA5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036803 name: Q4VAU3_HUMAN def: "CDX1 protein" [UniProtKB:Q4VAU3] xref: EMBL:AAH96252.2 xref: EMBL:AAI27123.2 xref: UniProtKB:Q4VAU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011291 ! CDX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036805 name: PDX1_HUMAN def: "Pancreas/duodenum homeobox protein 1" [UniProtKB:P52945] synonym: "Glucose-sensitive factor" EXACT [UniProtKB:P52945] synonym: "GSF" EXACT [UniProtKB:P52945] synonym: "IDX-1" EXACT [UniProtKB:P52945] synonym: "Insulin promoter factor 1" EXACT [UniProtKB:P52945] synonym: "Insulin upstream factor 1" EXACT [UniProtKB:P52945] synonym: "IPF-1" EXACT [UniProtKB:P52945] synonym: "Islet/duodenum homeobox-1" EXACT [UniProtKB:P52945] synonym: "IUF-1" EXACT [UniProtKB:P52945] synonym: "PDX-1" EXACT [UniProtKB:P52945] synonym: "Somatostatin-transactivating factor 1" EXACT [UniProtKB:P52945] synonym: "STF-1" EXACT [UniProtKB:P52945] xref: EMBL:AAA74012.1 xref: EMBL:AAA88820.1 xref: EMBL:AAB47101.1 xref: EMBL:AAB88463.1 xref: EMBL:AAC05157.1 xref: EMBL:CAA68169.1 xref: UniProtKB:O60594 xref: UniProtKB:P52945 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011597 ! PDX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0036807 name: CDX1_HUMAN def: "Homeobox protein CDX-1" [UniProtKB:P47902] synonym: "Caudal-type homeobox protein 1" EXACT [UniProtKB:P47902] xref: EMBL:AAA80284.1 xref: EMBL:AAB40602.1 xref: EMBL:AAC50237.1 xref: EMBL:AAF61234.1 xref: EMBL:AAH96251.1 xref: UniProtKB:P47902 xref: UniProtKB:Q4VAU4 xref: UniProtKB:Q9NYK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011291 ! CDX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036808 name: Q86TF7_HUMAN def: "Homeobox C4" [UniProtKB:Q86TF7] xref: EMBL:AAH50442.1 xref: UniProtKB:Q86TF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011474 ! HOXC4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036810 name: GSX1_HUMAN def: "GS homeobox 1" [UniProtKB:Q9H4S2] synonym: "Homeobox protein GSH-1" EXACT [UniProtKB:Q9H4S2] xref: EMBL:BAB78692.1 xref: EMBL:BAB78693.1 xref: EMBL:CAC12721.1 xref: UniProtKB:Q9H4S2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011450 ! GSX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0036813 name: HXC5_HUMAN def: "Homeobox protein Hox-C5" [UniProtKB:Q00444] synonym: "CP11" EXACT [UniProtKB:Q00444] synonym: "Hox-3D" EXACT [UniProtKB:Q00444] xref: EMBL:CAA43894.1 xref: UniProtKB:Q00444 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011475 ! HOXC5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036814 name: HXA6_HUMAN def: "Homeobox protein Hox-A6" [UniProtKB:P31267] synonym: "Hox-1B" EXACT [UniProtKB:P31267] xref: EMBL:AAH69497.1 xref: EMBL:AAI04916.1 xref: EMBL:AAI04918.1 xref: UniProtKB:P31267 xref: UniProtKB:Q2M3G3 xref: UniProtKB:Q9UPM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011466 ! HOXA6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036816 name: HXC4_HUMAN def: "Homeobox protein Hox-C4" [UniProtKB:P09017] synonym: "CP19" EXACT [UniProtKB:P09017] synonym: "Hox-3E" EXACT [UniProtKB:P09017] xref: EMBL:AAG42145.1 xref: EMBL:CAA30376.1 xref: UniProtKB:P09017 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011474 ! HOXC4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036818 name: HXC6_HUMAN def: "Homeobox protein Hox-C6" [UniProtKB:P09630] synonym: "CP25" EXACT [UniProtKB:P09630] synonym: "HHO.C8" EXACT [UniProtKB:P09630] synonym: "Hox-3C" EXACT [UniProtKB:P09630] xref: EMBL:AAA36007.1 xref: EMBL:AAB46892.1 xref: EMBL:AAH74844.1 xref: EMBL:AAH74845.1 xref: UniProtKB:P09630 xref: UniProtKB:Q6DK09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011476 ! HOXC6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036820 name: Q9UD61_HUMAN def: "HPX homeobox protein" [UniProtKB:Q9UD61] xref: UniProtKB:Q9UD61 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036821 name: HXD8_HUMAN def: "Homeobox protein Hox-D8" [UniProtKB:P13378] synonym: "Hox-4E" EXACT [UniProtKB:P13378] synonym: "Hox-5.4" EXACT [UniProtKB:P13378] xref: EMBL:AAG42152.1 xref: EMBL:CAA33529.1 xref: UniProtKB:P13378 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011479 ! HOXD8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036822 name: O75805_HUMAN def: "HOXA-9A" [UniProtKB:O75805] xref: EMBL:AAC23704.1 xref: UniProtKB:O75805 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011838 ! HOXA-9_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036823 name: MNX1_HUMAN def: "Motor neuron and pancreas homeobox protein 1" [UniProtKB:P50219] synonym: "Homeobox protein HB9" EXACT [UniProtKB:P50219] xref: EMBL:AAB60647.1 xref: EMBL:AAD41467.1 xref: UniProtKB:P50219 xref: UniProtKB:Q9Y648 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011538 ! MNX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068246 ! MNX1_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0068247 ! MNX1_HUMAN-Phosphoserine79 [Term] id: CCO:B0036825 name: HXA4_HUMAN def: "Homeobox protein Hox-A4" [UniProtKB:Q00056] synonym: "Hox-1.4" EXACT [UniProtKB:Q00056] synonym: "Hox-1D" EXACT [UniProtKB:Q00056] xref: EMBL:AAA53290.1 xref: EMBL:AAA58664.1 xref: UniProtKB:O43366 xref: UniProtKB:Q00056 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011464 ! HOXA4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036826 name: HXB6_HUMAN def: "Homeobox protein Hox-B6" [UniProtKB:P17509] synonym: "Hox-2.2" EXACT [UniProtKB:P17509] synonym: "Hox-2B" EXACT [UniProtKB:P17509] synonym: "HU-2" EXACT [UniProtKB:P17509] xref: EMBL:AAA36004.1 xref: EMBL:AAG31552.1 xref: EMBL:AAH14651.1 xref: EMBL:CAA41335.1 xref: EMBL:CAA41336.1 xref: EMBL:CAB65909.1 xref: UniProtKB:P09068 xref: UniProtKB:P17509 xref: UniProtKB:Q9HB11 xref: UniProtKB:Q9UGH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011470 ! HOXB6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014999 ! hoxb6-sat physical interaction relationship: participates_in CCO:I0015309 ! hoxb6-plscr1 physical interaction relationship: participates_in CCO:I0015531 ! hoxb6-krt15 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0039460 ! HXB6_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0039461 ! HXB6_HUMAN-Phosphoserine214 [Term] id: CCO:B0036827 name: HXC8_HUMAN def: "Homeobox protein Hox-C8" [UniProtKB:P31273] synonym: "Hox-3A" EXACT [UniProtKB:P31273] xref: EMBL:AAG42146.1 xref: EMBL:AAH53898.1 xref: EMBL:CAA67996.1 xref: EMBL:CAA67997.1 xref: UniProtKB:O15221 xref: UniProtKB:O15362 xref: UniProtKB:P31273 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011477 ! HOXC8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036828 name: HXD9_HUMAN def: "Homeobox protein Hox-D9" [UniProtKB:P28356] synonym: "Hox-4C" EXACT [UniProtKB:P28356] synonym: "Hox-5.2" EXACT [UniProtKB:P28356] xref: EMBL:AAH44855.2 xref: EMBL:CAA33528.1 xref: EMBL:CAA42016.1 xref: UniProtKB:P28356 xref: UniProtKB:Q86ST1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011480 ! HOXD9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036829 name: CDX2_HUMAN def: "Homeobox protein CDX-2" [UniProtKB:Q99626] synonym: "Caudal-type homeobox protein 2" EXACT [UniProtKB:Q99626] synonym: "CDX-3" EXACT [UniProtKB:Q99626] xref: EMBL:AAB40603.1 xref: EMBL:AAD05200.1 xref: EMBL:AAH14461.1 xref: EMBL:CAA74038.1 xref: EMBL:CAB94779.1 xref: EMBL:CAH70633.1 xref: UniProtKB:O00503 xref: UniProtKB:Q5VTU7 xref: UniProtKB:Q969L8 xref: UniProtKB:Q99626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011292 ! CDX2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0039354 ! CDX2_HUMAN-Phosphoserine60 [Term] id: CCO:B0036830 name: A8MYQ3_HUMAN def: "Putative uncharacterized protein HOXD9" [UniProtKB:A8MYQ3] xref: UniProtKB:A8MYQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011480 ! HOXD9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036831 name: A1L0T6_HUMAN def: "HOXA4 protein" [UniProtKB:A1L0T6] xref: EMBL:AAI26995.2 xref: UniProtKB:A1L0T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011464 ! HOXA4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036832 name: GSX2_HUMAN def: "GS homeobox 2" [UniProtKB:Q9BZM3] synonym: "Homeobox protein GSH-2" EXACT [UniProtKB:Q9BZM3] xref: EMBL:AAH75089.1 xref: EMBL:AAH75090.1 xref: EMBL:AAK00880.1 xref: EMBL:AAM08285.1 xref: EMBL:BAB84822.1 xref: UniProtKB:Q9BZM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011451 ! GSX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036835 name: Q16124_HUMAN def: "HOX B6 protein" [UniProtKB:Q16124] xref: EMBL:AAD14028.1 xref: UniProtKB:Q16124 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011848 ! HOX B6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036838 name: HXB9_HUMAN def: "Homeobox protein Hox-B9" [UniProtKB:P17482] synonym: "Hox-2.5" EXACT [UniProtKB:P17482] synonym: "Hox-2E" EXACT [UniProtKB:P17482] xref: EMBL:AAG42144.1 xref: EMBL:AAH15565.1 xref: EMBL:CAA34294.1 xref: UniProtKB:P17482 xref: UniProtKB:Q9H1I1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011473 ! HOXB9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015174 ! hoxb9-krtap4_12 physical interaction relationship: participates_in CCO:I0015404 ! hoxb9-mdfi physical interaction relationship: participates_in CCO:I0015653 ! hoxb9-rbpms physical interaction relationship: participates_in CCO:I0015739 ! hoxb9-sat physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0036875 name: EXOC5_HUMAN def: "Exocyst complex component 5" [UniProtKB:O00471] synonym: "Exocyst complex component Sec10" EXACT [UniProtKB:O00471] synonym: "hSec10" EXACT [UniProtKB:O00471] xref: EMBL:AAB53388.1 xref: UniProtKB:O00471 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011382 ! EXOC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019155 ! prkcg-exoc5 physical interaction [Term] id: CCO:B0036929 name: A4D1Z4_HUMAN def: "KIAA0415 gene product" [UniProtKB:A4D1Z4] xref: EMBL:EAL23965.1 xref: UniProtKB:A4D1Z4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011499 ! KIAA0415_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0036934 name: HNF4A_HUMAN def: "Hepatocyte nuclear factor 4-alpha" [UniProtKB:P41235] synonym: "HNF-4-alpha" EXACT [UniProtKB:P41235] synonym: "Nuclear receptor subfamily 2 group A member 1" EXACT [UniProtKB:P41235] synonym: "Transcription factor 14" EXACT [UniProtKB:P41235] synonym: "Transcription factor HNF-4" EXACT [UniProtKB:P41235] xref: EMBL:AAB48082.1 xref: EMBL:AAB48083.1 xref: EMBL:AAT91237.1 xref: EMBL:AAT91238.1 xref: EMBL:AAT91239.1 xref: EMBL:CAA54248.1 xref: EMBL:CAA61133.1 xref: EMBL:CAA61134.1 xref: EMBL:CAA61135.1 xref: EMBL:CAA89989.1 xref: EMBL:CAC01303.1 xref: EMBL:CAI18856.1 xref: UniProtKB:O00659 xref: UniProtKB:O00723 xref: UniProtKB:P41235 xref: UniProtKB:Q14540 xref: UniProtKB:Q5QPB8 xref: UniProtKB:Q6B4V5 xref: UniProtKB:Q6B4V6 xref: UniProtKB:Q6B4V7 xref: UniProtKB:Q92653 xref: UniProtKB:Q92654 xref: UniProtKB:Q92655 xref: UniProtKB:Q99864 xref: UniProtKB:Q9NQH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008676 ! HNF4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0039457 ! HNF4A_HUMAN-Phosphothreonine429 relationship: transforms_into CCO:B0039458 ! HNF4A_HUMAN-Phosphothreonine432 [Term] id: CCO:B0036936 name: Q6FGL6_HUMAN def: "HNF4G protein" [UniProtKB:Q6FGL6] xref: EMBL:CAG46888.1 xref: UniProtKB:Q6FGL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008840 ! HNF4G_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0036939 name: HNF4G_HUMAN def: "Hepatocyte nuclear factor 4-gamma" [UniProtKB:Q14541] synonym: "HNF-4-gamma" EXACT [UniProtKB:Q14541] synonym: "Nuclear receptor subfamily 2 group A member 2" EXACT [UniProtKB:Q14541] xref: EMBL:AAF00110.1 xref: EMBL:CAA89990.2 xref: UniProtKB:Q14541 xref: UniProtKB:Q9UH81 xref: UniProtKB:Q9UIS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008840 ! HNF4G_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0036957 name: HPRT_HUMAN def: "Hypoxanthine-guanine phosphoribosyltransferase" [UniProtKB:P00492] synonym: "EC 2.4.2.8" EXACT [UniProtKB:P00492] synonym: "HGPRT" EXACT [UniProtKB:P00492] synonym: "HGPRTase" EXACT [UniProtKB:P00492] xref: EMBL:AAA36012.1 xref: EMBL:AAA52690.1 xref: EMBL:AAA52691.1 xref: EMBL:AAB21289.1 xref: EMBL:AAB59391.1 xref: EMBL:AAB59392.1 xref: EMBL:AAC60591.2 xref: EMBL:AAH00578.1 xref: EMBL:AAV31777.1 xref: EMBL:AAV38157.1 xref: EMBL:EAX11761.1 xref: UniProtKB:A6NHF0 xref: UniProtKB:P00492 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011462 ! HPRT1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000831 ! hypoxanthine phosphoribosyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015396 ! c8orf32-hprt1 physical interaction relationship: participates_in CCO:I0015797 ! hhgp-hprt1 physical interaction relationship: participates_in CCO:P0002643 ! positive regulation of dopamine metabolic process relationship: transforms_into CCO:B0039459 ! HPRT_HUMAN-N-acetylalanine2 [Term] id: CCO:B0037015 name: Q1ZYL3_HUMAN def: "Rho guanine nucleotide exchange factor 4 variant 1" [UniProtKB:Q1ZYL3] xref: EMBL:ABD83670.1 xref: UniProtKB:Q1ZYL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0037017 name: ARHG4_HUMAN def: "Rho guanine nucleotide exchange factor 4" [UniProtKB:Q9NR80] synonym: "APC-stimulated guanine nucleotide exchange factor" EXACT [UniProtKB:Q9NR80] synonym: "Asef" EXACT [UniProtKB:Q9NR80] xref: EMBL:AAF79955.1 xref: EMBL:BAA83064.1 xref: EMBL:BAB11941.1 xref: UniProtKB:Q9HDC6 xref: UniProtKB:Q9NR80 xref: UniProtKB:Q9UPP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011251 ! ARHGEF4_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0037018 name: PREX2_HUMAN def: "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein" [UniProtKB:Q70Z35] synonym: "DEP domain-containing protein 2" EXACT [UniProtKB:Q70Z35] synonym: "P-Rex2" EXACT [UniProtKB:Q70Z35] synonym: "PtdIns(3,4,5)-dependent Rac exchanger 2" EXACT [UniProtKB:Q70Z35] xref: EMBL:AAS82571.1 xref: EMBL:AAS82572.1 xref: EMBL:BAB14375.1 xref: EMBL:BAB14818.1 xref: EMBL:CAD26885.2 xref: EMBL:DAA05333.1 xref: EMBL:DAA05334.1 xref: UniProtKB:Q32KL0 xref: UniProtKB:Q32KL1 xref: UniProtKB:Q6R7Q3 xref: UniProtKB:Q6R7Q4 xref: UniProtKB:Q70Z35 xref: UniProtKB:Q9H805 xref: UniProtKB:Q9H961 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011890 ! PREX2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004517 ! Rac GTPase activator activity relationship: has_function CCO:F0004518 ! Rac guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0037019 name: SPT13_HUMAN def: "Spermatogenesis-associated protein 13" [UniProtKB:Q96N96] xref: EMBL:AAI09291.1 xref: EMBL:AAI09292.1 xref: EMBL:BAB71009.1 xref: EMBL:BAB84943.1 xref: EMBL:BAC04977.1 xref: EMBL:BAD18714.1 xref: EMBL:CAH72289.1 xref: UniProtKB:Q6ZML1 xref: UniProtKB:Q8N873 xref: UniProtKB:Q8TEK6 xref: UniProtKB:Q96N96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011685 ! SPATA13_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0037020 name: DEPD6_HUMAN def: "DEP domain-containing protein 6" [UniProtKB:Q8TB45] xref: EMBL:AAH12040.1 xref: EMBL:AAH24746.1 xref: EMBL:BAB14054.1 xref: EMBL:BAB14723.1 xref: EMBL:CAB66613.1 xref: UniProtKB:Q8TB45 xref: UniProtKB:Q96EQ1 xref: UniProtKB:Q9H0R7 xref: UniProtKB:Q9H894 xref: UniProtKB:Q9HA07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011343 ! DEPDC6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0039380 ! DEPD6_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0039381 ! DEPD6_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0039382 ! DEPD6_HUMAN-Phosphoserine287 [Term] id: CCO:B0037021 name: PREX1_HUMAN def: "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein" [UniProtKB:Q8TCU6] synonym: "P-Rex1" EXACT [UniProtKB:Q8TCU6] synonym: "PtdIns(3,4,5)-dependent Rac exchanger 1" EXACT [UniProtKB:Q8TCU6] xref: EMBL:AAH53616.1 xref: EMBL:BAA92653.2 xref: EMBL:CAB66514.1 xref: EMBL:CAC86401.1 xref: EMBL:CAH10614.1 xref: EMBL:CAI23274.1 xref: EMBL:CAI39886.1 xref: EMBL:CAI43186.1 xref: UniProtKB:Q5JS95 xref: UniProtKB:Q5JS96 xref: UniProtKB:Q69YL2 xref: UniProtKB:Q7Z2L9 xref: UniProtKB:Q8TCU6 xref: UniProtKB:Q9BQH0 xref: UniProtKB:Q9BX55 xref: UniProtKB:Q9H4Q6 xref: UniProtKB:Q9P2D2 xref: UniProtKB:Q9UGQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011628 ! PREX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0039596 ! PREX1_HUMAN-Phosphoserine436 [Term] id: CCO:B0037023 name: Q5VX68_HUMAN def: "Spermatogenesis associated 13 (Putative uncharacterized protein SPATA13) (cDNA FLJ41035 fis, clone HLUNG2002465, highly similar to Homo sapiens spermatogenesis associated 13 (SPATA13), mRNA)" [UniProtKB:Q5VX68] xref: EMBL:BAG53856.1 xref: EMBL:CAH72290.2 xref: UniProtKB:A6NF85 xref: UniProtKB:Q5VX68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011685 ! SPATA13_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0037024 name: ARHG9_HUMAN def: "Rho guanine nucleotide exchange factor 9" [UniProtKB:O43307] synonym: "Collybistin" EXACT [UniProtKB:O43307] synonym: "PEM-2 homolog" EXACT [UniProtKB:O43307] synonym: "Rac/Cdc42 guanine nucleotide exchange factor 9" EXACT [UniProtKB:O43307] xref: EMBL:AAI17407.1 xref: EMBL:BAA24854.2 xref: EMBL:CAI39550.1 xref: EMBL:CAI40401.1 xref: EMBL:CAI41195.1 xref: UniProtKB:O43307 xref: UniProtKB:Q5JSL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011252 ! ARHGEF9_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0037027 name: RMD5B_HUMAN def: "Protein RMD5 homolog B" [UniProtKB:Q96G75] xref: EMBL:AAH09911.1 xref: EMBL:AAQ89450.1 xref: EMBL:BAB15303.1 xref: EMBL:CAD28476.1 xref: UniProtKB:Q6UVY7 xref: UniProtKB:Q96G75 xref: UniProtKB:Q9H6F6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011660 ! RMND5B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015161 ! ewsr1-flj22318 physical interaction [Term] id: CCO:B0037049 name: TRI66_HUMAN def: "Tripartite motif-containing protein 66" [UniProtKB:O15016] xref: EMBL:BAA20758.2 xref: EMBL:CAC35389.1 xref: UniProtKB:O15016 xref: UniProtKB:Q9BQQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011720 ! TRIM66_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000299 ! polytene chromosome chromocenter relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0037050 name: TRI33_HUMAN def: "E3 ubiquitin-protein ligase TRIM33" [UniProtKB:Q9UPN9] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9UPN9] synonym: "Ectodermin homolog" EXACT [UniProtKB:Q9UPN9] synonym: "Protein Rfg7" EXACT [UniProtKB:Q9UPN9] synonym: "RET-fused gene 7 protein" EXACT [UniProtKB:Q9UPN9] synonym: "TIF1-gamma" EXACT [UniProtKB:Q9UPN9] synonym: "Transcription intermediary factor 1-gamma" EXACT [UniProtKB:Q9UPN9] synonym: "Tripartite motif-containing protein 33" EXACT [UniProtKB:Q9UPN9] xref: EMBL:AAD17259.1 xref: EMBL:AAG53509.1 xref: EMBL:AAG53510.1 xref: EMBL:BAA83065.1 xref: EMBL:CAB55313.1 xref: EMBL:CAI13548.1 xref: EMBL:CAI13550.1 xref: EMBL:CAI13551.1 xref: EMBL:CAI21895.1 xref: EMBL:CAI21896.1 xref: EMBL:CAI21897.1 xref: UniProtKB:O95855 xref: UniProtKB:Q5TG72 xref: UniProtKB:Q5TG73 xref: UniProtKB:Q5TG74 xref: UniProtKB:Q9C017 xref: UniProtKB:Q9UJ79 xref: UniProtKB:Q9UPN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011719 ! TRIM33_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0071556 ! TRI33_HUMAN-Phosphothreonine505 relationship: transforms_into CCO:B0071557 ! TRI33_HUMAN-Phosphoserine862 relationship: transforms_into CCO:B0071558 ! TRI33_HUMAN-Phosphothreonine1102 relationship: transforms_into CCO:B0071559 ! TRI33_HUMAN-Phosphoserine1105 relationship: transforms_into CCO:B0071560 ! TRI33_HUMAN-Phosphoserine1119 [Term] id: CCO:B0037051 name: TIF1A_HUMAN def: "Transcription intermediary factor 1-alpha" [UniProtKB:O15164] synonym: "RING finger protein 82" EXACT [UniProtKB:O15164] synonym: "TIF1-alpha" EXACT [UniProtKB:O15164] synonym: "Tripartite motif-containing protein 24" EXACT [UniProtKB:O15164] xref: EMBL:AAB63585.1 xref: EMBL:AAD17258.1 xref: EMBL:AAH28689.2 xref: UniProtKB:O15164 xref: UniProtKB:O95854 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011710 ! TRIM24_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039678 ! TIF1A_HUMAN-Phosphoserine768 relationship: transforms_into CCO:B0039679 ! TIF1A_HUMAN-Phosphoserine811 [Term] id: CCO:B0037083 name: RXFP2_HUMAN def: "Relaxin receptor 2" [UniProtKB:Q8WXD0] synonym: "G-protein coupled receptor 106" EXACT [UniProtKB:Q8WXD0] synonym: "G-protein coupled receptor affecting testicular descent" EXACT [UniProtKB:Q8WXD0] synonym: "Leucine-rich repeat-containing G-protein coupled receptor 8" EXACT [UniProtKB:Q8WXD0] synonym: "Relaxin family peptide receptor 2" EXACT [UniProtKB:Q8WXD0] xref: EMBL:AAL69324.2 xref: EMBL:AAL73946.1 xref: UniProtKB:Q8WXD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011668 ! RXFP2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037085 name: RXFP1_HUMAN def: "Relaxin receptor 1" [UniProtKB:Q9HBX9] synonym: "Leucine-rich repeat-containing G-protein coupled receptor 7" EXACT [UniProtKB:Q9HBX9] synonym: "Relaxin family peptide receptor 1" EXACT [UniProtKB:Q9HBX9] xref: EMBL:AAG17167.1 xref: EMBL:AAI12143.1 xref: EMBL:AAI13618.1 xref: EMBL:AAX85196.1 xref: EMBL:AAX85197.1 xref: EMBL:AAX85198.1 xref: EMBL:EAX04856.1 xref: UniProtKB:Q2M215 xref: UniProtKB:Q3KU24 xref: UniProtKB:Q3KU25 xref: UniProtKB:Q3KU26 xref: UniProtKB:Q9HBX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011667 ! RXFP1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037087 name: Q3KU23_HUMAN def: "LGR8.1" [UniProtKB:Q3KU23] xref: EMBL:AAX85199.1 xref: UniProtKB:Q3KU23 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037089 name: ZN100_HUMAN def: "Zinc finger protein 100" [UniProtKB:Q8IYN0] xref: EMBL:AAH35579.1 xref: UniProtKB:Q7M4M0 xref: UniProtKB:Q8IYN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011747 ! ZNF100_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037090 name: ZN479_HUMAN def: "Zinc finger protein 479" [UniProtKB:Q96JC4] synonym: "HKr19" EXACT [UniProtKB:Q96JC4] synonym: "Zinc finger protein Kr19" EXACT [UniProtKB:Q96JC4] xref: EMBL:AAK61307.1 xref: UniProtKB:Q96JC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011758 ! ZNF479_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037092 name: ZN682_HUMAN def: "Zinc finger protein 682" [UniProtKB:O95780] xref: EMBL:AAD14472.1 xref: EMBL:BAB55408.1 xref: UniProtKB:O95780 xref: UniProtKB:Q96JV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011763 ! ZNF682_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037093 name: ZN680_HUMAN def: "Zinc finger protein 680" [UniProtKB:Q8NEM1] xref: EMBL:AAH30700.1 xref: EMBL:BAC11286.1 xref: UniProtKB:Q8NC79 xref: UniProtKB:Q8NEM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011762 ! ZNF680_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037094 name: Q6ZMM5_HUMAN xref: UniProtKB:Q6ZMM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037096 name: ZN626_HUMAN def: "Zinc finger protein 626" [UniProtKB:Q68DY1] xref: EMBL:BAC04729.1 xref: EMBL:CAH18089.1 xref: UniProtKB:Q68DY1 xref: UniProtKB:Q8N8T4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011761 ! ZNF626_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037097 name: Q96M04_HUMAN xref: UniProtKB:Q96M04 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037098 name: ZN429_HUMAN def: "Zinc finger protein 429" [UniProtKB:Q86V71] xref: EMBL:AAP30884.1 xref: UniProtKB:Q86V71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011755 ! ZNF429_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039725 ! ZN429_HUMAN-Phosphothreonine364 [Term] id: CCO:B0037101 name: ZN431_HUMAN def: "Zinc finger protein 431" [UniProtKB:Q8TF32] xref: EMBL:AAH40506.1 xref: EMBL:BAB85555.1 xref: UniProtKB:Q8IWC4 xref: UniProtKB:Q8TF32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011757 ! ZNF431_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037103 name: A4FVA7_HUMAN def: "Zinc finger protein 253" [UniProtKB:A4FVA7] xref: EMBL:AAI25064.1 xref: UniProtKB:A4FVA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011799 ! ZNF253_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037105 name: ZN273_HUMAN def: "Zinc finger protein 273" [UniProtKB:Q14593] synonym: "HZF9" EXACT [UniProtKB:Q14593] synonym: "Zinc finger protein 9" EXACT [UniProtKB:Q14593] xref: EMBL:AAH63818.1 xref: EMBL:CAA55532.1 xref: UniProtKB:Q14593 xref: UniProtKB:Q6P3V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011752 ! ZNF273_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037109 name: O95779_HUMAN def: "BC39498_2 (Zinc finger protein 682, isoform CRA_b)" [UniProtKB:O95779] xref: EMBL:AAD14470.1 xref: EMBL:EAW84869.1 xref: UniProtKB:O95779 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011763 ! ZNF682_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037110 name: ZNF92_HUMAN def: "Zinc finger protein 92" [UniProtKB:Q03936] synonym: "Zinc finger protein HTF12" EXACT [UniProtKB:Q03936] xref: EMBL:AAA58673.1 xref: EMBL:AAH36439.1 xref: EMBL:AAH40594.1 xref: EMBL:BAC03708.1 xref: UniProtKB:A6NNF9 xref: UniProtKB:Q03936 xref: UniProtKB:Q8N492 xref: UniProtKB:Q8NB35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011769 ! ZNF92_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037112 name: ZN430_HUMAN def: "Zinc finger protein 430" [UniProtKB:Q9H8G1] xref: EMBL:AAP30885.1 xref: EMBL:BAB14656.1 xref: UniProtKB:Q86V70 xref: UniProtKB:Q9H8G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011756 ! ZNF430_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037117 name: TNIP2_HUMAN def: "TNFAIP3-interacting protein 2" [UniProtKB:Q8NFZ5] synonym: "A20-binding inhibitor of NF-kappa-B activation 2" EXACT [UniProtKB:Q8NFZ5] synonym: "ABIN-2" EXACT [UniProtKB:Q8NFZ5] synonym: "Fetal liver LKB1-interacting protein" EXACT [UniProtKB:Q8NFZ5] xref: EMBL:AAH02740.2 xref: EMBL:AAM21315.1 xref: EMBL:BAB15382.1 xref: EMBL:CAC34835.1 xref: EMBL:EAW82514.1 xref: UniProtKB:Q7L5L2 xref: UniProtKB:Q8NFZ5 xref: UniProtKB:Q9BQR6 xref: UniProtKB:Q9H682 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011718 ! TNIP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017155 ! rel-flip1 physical interaction relationship: participates_in CCO:I0017187 ! nfkb2-flip1 physical interaction [Term] id: CCO:B0037120 name: ZN295_HUMAN def: "Zinc finger protein 295" [UniProtKB:Q9ULJ3] synonym: "Zinc finger and BTB domain-containing protein 21" EXACT [UniProtKB:Q9ULJ3] xref: EMBL:AAH63290.1 xref: EMBL:BAA86541.1 xref: EMBL:BAA95529.1 xref: UniProtKB:Q6P4R0 xref: UniProtKB:Q9ULJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011753 ! ZNF295_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039716 ! ZN295_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0039717 ! ZN295_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0039718 ! ZN295_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0039719 ! ZN295_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0039720 ! ZN295_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0039721 ! ZN295_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0039722 ! ZN295_HUMAN-Phosphoserine714 relationship: transforms_into CCO:B0039723 ! ZN295_HUMAN-Phosphoserine983 relationship: transforms_into CCO:B0039724 ! ZN295_HUMAN-Phosphoserine1003 relationship: transforms_into CCO:B0072092 ! ZN295_HUMAN-Phosphothreonine431 relationship: transforms_into CCO:B0072093 ! ZN295_HUMAN-Phosphoserine434 relationship: transforms_into CCO:B0072094 ! ZN295_HUMAN-Phosphoserine438 relationship: transforms_into CCO:B0072095 ! ZN295_HUMAN-Phosphoserine605 relationship: transforms_into CCO:B0072096 ! ZN295_HUMAN-Phosphoserine759 [Term] id: CCO:B0037130 name: DJB12_HUMAN def: "DnaJ homolog subfamily B member 12" [UniProtKB:Q9NXW2] xref: EMBL:AAH11812.2 xref: EMBL:AAH64920.1 xref: EMBL:BAA90896.1 xref: EMBL:BAB15289.1 xref: UniProtKB:Q9H6H0 xref: UniProtKB:Q9NXW2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011348 ! DNAJB12_human relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017000 ! tnfrsf1a-dnajb12 physical interaction [Term] id: CCO:B0037138 name: ZF64B_HUMAN def: "Zinc finger protein 64 homolog, isoforms 3 and 4" [UniProtKB:Q9NTW7] synonym: "Zfp-64" EXACT [UniProtKB:Q9NTW7] synonym: "Zinc finger protein 338" EXACT [UniProtKB:Q9NTW7] xref: EMBL:AAH21087.1 xref: EMBL:BAB14182.1 xref: EMBL:CAB86405.2 xref: UniProtKB:Q8WU98 xref: UniProtKB:Q9H9P1 xref: UniProtKB:Q9NTW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011745 ! ZFP64_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015628 ! begain-zfp64 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037139 name: ZF64A_HUMAN def: "Zinc finger protein 64 homolog, isoforms 1 and 2" [UniProtKB:Q9NPA5] synonym: "Zfp-64" EXACT [UniProtKB:Q9NPA5] synonym: "Zinc finger protein 338" EXACT [UniProtKB:Q9NPA5] xref: EMBL:AAH12759.1 xref: EMBL:AAH41622.1 xref: EMBL:BAA91777.1 xref: EMBL:BAA91876.1 xref: EMBL:CAB90276.1 xref: EMBL:CAB90277.1 xref: UniProtKB:Q9NPA5 xref: UniProtKB:Q9NTS7 xref: UniProtKB:Q9NVH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011745 ! ZFP64_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019554 ! zfp64-tle1 physical interaction relationship: participates_in CCO:I0019879 ! zfp64-setdb1 physical interaction relationship: participates_in CCO:I0019880 ! zfp64-unc119 physical interaction relationship: participates_in CCO:I0020497 ! zfp64-c14orf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039714 ! ZF64A_HUMAN-Phosphothreonine473 relationship: transforms_into CCO:B0039715 ! ZF64A_HUMAN-Phosphoserine487 [Term] id: CCO:B0037152 name: DUS16_HUMAN def: "Dual specificity protein phosphatase 16" [UniProtKB:Q9BY84] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9BY84] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9BY84] synonym: "MAP kinase phosphatase 7" EXACT [UniProtKB:Q9BY84] synonym: "Mitogen-activated protein kinase phosphatase 7" EXACT [UniProtKB:Q9BY84] synonym: "MKP-7" EXACT [UniProtKB:Q9BY84] xref: EMBL:AAI09236.1 xref: EMBL:AAN75120.1 xref: EMBL:BAB21791.1 xref: EMBL:BAB40814.1 xref: UniProtKB:Q547C7 xref: UniProtKB:Q9BY84 xref: UniProtKB:Q9C0G3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011368 ! DUSP16_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: transforms_into CCO:B0064905 ! DUS16_HUMAN-Phosphoserine501 [Term] id: CCO:B0037159 name: DUS8_HUMAN def: "Dual specificity protein phosphatase 8" [UniProtKB:Q13202] synonym: "Dual specificity protein phosphatase hVH-5" EXACT [UniProtKB:Q13202] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q13202] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q13202] xref: EMBL:AAA83151.1 xref: UniProtKB:Q13202 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011372 ! DUSP8_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity [Term] id: CCO:B0037223 name: A8MSY3_HUMAN def: "Putative uncharacterized protein PTGER3" [UniProtKB:A8MSY3] xref: UniProtKB:A8MSY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011598 ! PTGER3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037226 name: O00325_HUMAN def: "Prostaglandin EP3 receptor subtype isoform" [UniProtKB:O00325] synonym: "Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_g" EXACT [UniProtKB:O00325] xref: EMBL:BAA19958.1 xref: EMBL:EAX06442.1 xref: UniProtKB:O00325 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011598 ! PTGER3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037228 name: Q5CZ60_HUMAN def: "EP3f protein (Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_a)" [UniProtKB:Q5CZ60] xref: EMBL:BAA19955.1 xref: EMBL:EAX06436.1 xref: UniProtKB:Q5CZ60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011894 ! EP3f_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037229 name: PE2R3_HUMAN def: "Prostaglandin E2 receptor EP3 subtype" [UniProtKB:P43115] synonym: "PGE receptor, EP3 subtype" EXACT [UniProtKB:P43115] synonym: "PGE2-R" EXACT [UniProtKB:P43115] synonym: "Prostanoid EP3 receptor" EXACT [UniProtKB:P43115] xref: EMBL:AAA21130.1 xref: EMBL:AAA21131.1 xref: EMBL:AAA21132.1 xref: EMBL:AAA21133.1 xref: EMBL:AAA21134.1 xref: EMBL:AAA60076.1 xref: EMBL:AAA68191.1 xref: EMBL:AAA68192.1 xref: EMBL:AAA68193.1 xref: EMBL:AAB29854.1 xref: EMBL:AAB30208.1 xref: EMBL:AAC13372.1 xref: EMBL:AAC13373.1 xref: EMBL:AAC13374.1 xref: EMBL:AAH24229.1 xref: EMBL:AAR07903.1 xref: EMBL:BAA07416.1 xref: EMBL:BAA07417.1 xref: EMBL:BAA07418.1 xref: EMBL:BAA07419.1 xref: EMBL:BAA07420.1 xref: EMBL:BAA19951.1 xref: EMBL:BAA19959.1 xref: EMBL:CAA58737.1 xref: EMBL:CAA58738.1 xref: EMBL:CAA58739.1 xref: EMBL:CAA58740.1 xref: EMBL:CAA58741.1 xref: EMBL:CAA58742.1 xref: EMBL:CAA58743.1 xref: EMBL:CAB52459.1 xref: EMBL:CAI20226.1 xref: EMBL:CAI20227.1 xref: EMBL:CAI20228.1 xref: EMBL:CAI23437.1 xref: UniProtKB:O00326 xref: UniProtKB:P43115 xref: UniProtKB:Q12943 xref: UniProtKB:Q12944 xref: UniProtKB:Q12945 xref: UniProtKB:Q16546 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011598 ! PTGER3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037230 name: Q5CZ59_HUMAN def: "EP3e protein" [UniProtKB:Q5CZ59] xref: EMBL:BAA19954.1 xref: UniProtKB:Q5CZ59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011893 ! EP3e_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037231 name: Q5CZ62_HUMAN def: "EP3-V protein (Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_k)" [UniProtKB:Q5CZ62] xref: EMBL:BAA19952.1 xref: EMBL:EAX06446.1 xref: UniProtKB:Q5CZ62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011896 ! EP3-V_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037235 name: A8K3L9_HUMAN def: "cDNA FLJ77072, highly similar to Homo sapiens prostaglandin E receptor 3 (subtype EP3) (PTGER3), transcript variant 9, mRNA" [UniProtKB:A8K3L9] xref: EMBL:BAF83323.1 xref: UniProtKB:A8K3L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037236 name: Q147X8_HUMAN def: "PTGER3 protein" [UniProtKB:Q147X8] xref: EMBL:AAI18579.1 xref: UniProtKB:Q147X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011598 ! PTGER3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037269 name: PTBP1_HUMAN def: "Polypyrimidine tract-binding protein 1" [UniProtKB:P26599] synonym: "57 kDa RNA-binding protein PPTB-1" EXACT [UniProtKB:P26599] synonym: "Heterogeneous nuclear ribonucleoprotein I" EXACT [UniProtKB:P26599] synonym: "hnRNP I" EXACT [UniProtKB:P26599] synonym: "PTB" EXACT [UniProtKB:P26599] xref: EMBL:AAC99798.1 xref: EMBL:AAH04383.1 xref: EMBL:CAA43056.1 xref: EMBL:CAA43973.1 xref: EMBL:CAA46443.1 xref: EMBL:CAA46444.1 xref: EMBL:CAA47386.1 xref: UniProtKB:P26599 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011635 ! PTBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0016120 ! sfpq-ptbp1-1 physical interaction relationship: transforms_into CCO:B0039599 ! PTBP1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0039600 ! PTBP1_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0039601 ! PTBP1_HUMAN-Phosphoserine433 relationship: transforms_into CCO:B0069588 ! PTBP1_HUMAN-Phosphotyrosine127 [Term] id: CCO:B0037300 name: RRBP1_HUMAN def: "Ribosome-binding protein 1" [UniProtKB:Q9P2E9] synonym: "180 kDa ribosome receptor homolog" EXACT [UniProtKB:Q9P2E9] synonym: "ES/130-related protein" EXACT [UniProtKB:Q9P2E9] synonym: "Ribosome receptor protein" EXACT [UniProtKB:Q9P2E9] xref: EMBL:AAC25977.1 xref: EMBL:AAC25978.1 xref: EMBL:AAH00099.4 xref: EMBL:BAA92636.2 xref: EMBL:CAC10587.1 xref: EMBL:CAD38684.1 xref: EMBL:CAH74034.1 xref: UniProtKB:A2A2S6 xref: UniProtKB:A6NCN6 xref: UniProtKB:O75300 xref: UniProtKB:O75301 xref: UniProtKB:Q5W165 xref: UniProtKB:Q96SB2 xref: UniProtKB:Q9BWP1 xref: UniProtKB:Q9H476 xref: UniProtKB:Q9P2E9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011665 ! RRBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039642 ! RRBP1_HUMAN-Phosphothreonine255 relationship: transforms_into CCO:B0039643 ! RRBP1_HUMAN-Phosphothreonine275 relationship: transforms_into CCO:B0039644 ! RRBP1_HUMAN-Phosphoserine533 relationship: transforms_into CCO:B0039645 ! RRBP1_HUMAN-Phosphoserine583 relationship: transforms_into CCO:B0039646 ! RRBP1_HUMAN-Phosphoserine615 relationship: transforms_into CCO:B0070178 ! RRBP1_HUMAN-Phosphoserine1276 relationship: transforms_into CCO:B0070179 ! RRBP1_HUMAN-Phosphoserine1277 [Term] id: CCO:B0037391 name: MARK2_HUMAN def: "Serine/threonine-protein kinase MARK2" [UniProtKB:Q7KZI7] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q7KZI7] synonym: "ELKL motif kinase" EXACT [UniProtKB:Q7KZI7] synonym: "EMK1" EXACT [UniProtKB:Q7KZI7] synonym: "MAP/microtubule affinity-regulating kinase 2" EXACT [UniProtKB:Q7KZI7] synonym: "PAR1 homolog" EXACT [UniProtKB:Q7KZI7] xref: EMBL:AAH08771.2 xref: EMBL:AAH84540.1 xref: EMBL:AAK82368.1 xref: EMBL:AAP36006.1 xref: EMBL:BAD37141.1 xref: EMBL:CAA66229.1 xref: EMBL:CAA80914.1 xref: UniProtKB:Q15449 xref: UniProtKB:Q15524 xref: UniProtKB:Q5XGA3 xref: UniProtKB:Q68A18 xref: UniProtKB:Q7KZI7 xref: UniProtKB:Q96HB3 xref: UniProtKB:Q96RG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011527 ! MARK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018271 ! mark2-ywhaz-2 physical interaction relationship: participates_in CCO:I0019356 ! mark2-ywhaz-1 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0039506 ! MARK2_HUMAN-Phosphoserine40 relationship: transforms_into CCO:B0039507 ! MARK2_HUMAN-Phosphothreonine208 relationship: transforms_into CCO:B0039508 ! MARK2_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0039509 ! MARK2_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0039510 ! MARK2_HUMAN-Phosphothreonine469 relationship: transforms_into CCO:B0039511 ! MARK2_HUMAN-Phosphoserine479 relationship: transforms_into CCO:B0039512 ! MARK2_HUMAN-Phosphoserine486 relationship: transforms_into CCO:B0039513 ! MARK2_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0039514 ! MARK2_HUMAN-Phosphoserine571 relationship: transforms_into CCO:B0039515 ! MARK2_HUMAN-Phosphothreonine596 relationship: transforms_into CCO:B0039516 ! MARK2_HUMAN-Phosphoserine619 relationship: transforms_into CCO:B0039517 ! MARK2_HUMAN-Phosphoserine631 relationship: transforms_into CCO:B0067991 ! MARK2_HUMAN-Phosphothreonine42 relationship: transforms_into CCO:B0067992 ! MARK2_HUMAN-Phosphoserine576 relationship: transforms_into CCO:B0067993 ! MARK2_HUMAN-Phosphoserine621 [Term] id: CCO:B0037393 name: MARK1_HUMAN def: "Serine/threonine-protein kinase MARK1" [UniProtKB:Q9P0L2] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9P0L2] synonym: "MAP/microtubule affinity-regulating kinase 1" EXACT [UniProtKB:Q9P0L2] xref: EMBL:AAF72103.1 xref: EMBL:AAI13870.1 xref: EMBL:AAI14479.1 xref: EMBL:BAA96001.1 xref: EMBL:BAB55152.1 xref: EMBL:CAH72462.1 xref: EMBL:CAH72463.1 xref: UniProtKB:Q2HIY1 xref: UniProtKB:Q5VTF9 xref: UniProtKB:Q5VTG0 xref: UniProtKB:Q96SW9 xref: UniProtKB:Q9P0L2 xref: UniProtKB:Q9P251 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011526 ! MARK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0018270 ! mark1-ywhaz-1 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0039500 ! MARK1_HUMAN-Phosphothreonine215 relationship: transforms_into CCO:B0039501 ! MARK1_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0039502 ! MARK1_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0039503 ! MARK1_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0039504 ! MARK1_HUMAN-Phosphoserine649 relationship: transforms_into CCO:B0039505 ! MARK1_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0067989 ! MARK1_HUMAN-Phosphoserine588 relationship: transforms_into CCO:B0067990 ! MARK1_HUMAN-Phosphothreonine596 [Term] id: CCO:B0037398 name: PXK_HUMAN def: "PX domain-containing protein kinase-like protein" [UniProtKB:Q7Z7A4] synonym: "Modulator of Na,K-ATPase" EXACT [UniProtKB:Q7Z7A4] synonym: "MONaKA" EXACT [UniProtKB:Q7Z7A4] xref: EMBL:AAH08943.1 xref: EMBL:AAH14479.1 xref: EMBL:AAK94455.1 xref: EMBL:AAP42076.1 xref: EMBL:AAR98521.1 xref: EMBL:AAX73352.1 xref: EMBL:AAX73353.1 xref: EMBL:AAX73354.1 xref: EMBL:AAZ38821.1 xref: EMBL:AAZ38822.1 xref: EMBL:BAA91097.1 xref: EMBL:BAD18536.1 xref: EMBL:BAD92925.1 xref: UniProtKB:Q3BCH4 xref: UniProtKB:Q3BCH5 xref: UniProtKB:Q3BCH6 xref: UniProtKB:Q3BDW1 xref: UniProtKB:Q45L83 xref: UniProtKB:Q59EX3 xref: UniProtKB:Q6PK17 xref: UniProtKB:Q6ZN39 xref: UniProtKB:Q7Z7A4 xref: UniProtKB:Q96CA3 xref: UniProtKB:Q96R07 xref: UniProtKB:Q9NXB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011642 ! PXK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002958 ! regulation of synaptic transmission [Term] id: CCO:B0037399 name: SOX17_HUMAN def: "Transcription factor SOX-17" [UniProtKB:Q9H6I2] xref: EMBL:BAB15277.1 xref: EMBL:BAB83867.1 xref: UniProtKB:Q9H6I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011683 ! SOX17_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037429 name: CNRG_HUMAN def: "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma" [UniProtKB:P18545] synonym: "EC 3.1.4.17" EXACT [UniProtKB:P18545] synonym: "GMP-PDE gamma" EXACT [UniProtKB:P18545] xref: EMBL:AAA03653.1 xref: EMBL:AAA60044.1 xref: EMBL:AAI06885.1 xref: EMBL:CAA43975.1 xref: UniProtKB:P18545 xref: UniProtKB:Q3KP63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011305 ! PDE6G_human relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0002530 ! positive regulation of epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002533 ! positive regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037430 name: CNCG_HUMAN def: "Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma" [UniProtKB:Q13956] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q13956] synonym: "GMP-PDE gamma" EXACT [UniProtKB:Q13956] xref: EMBL:AAH69774.1 xref: EMBL:AAH69800.1 xref: EMBL:AAH93738.1 xref: EMBL:AAH93740.1 xref: EMBL:BAA08241.1 xref: UniProtKB:Q13956 xref: UniProtKB:Q52LY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011300 ! PDE6H_human relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0002530 ! positive regulation of epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002533 ! positive regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0037436 name: XPO5_HUMAN def: "Exportin-5" [UniProtKB:Q9HAV4] synonym: "Exp5" EXACT [UniProtKB:Q9HAV4] synonym: "Ran-binding protein 21" EXACT [UniProtKB:Q9HAV4] xref: EMBL:AAG17907.1 xref: EMBL:AAG53603.1 xref: EMBL:AAH00129.1 xref: EMBL:AAH08347.1 xref: EMBL:AAH09969.2 xref: EMBL:AAH62635.1 xref: EMBL:BAA86605.2 xref: EMBL:BAA91547.1 xref: EMBL:BAB14200.1 xref: EMBL:CAB70753.1 xref: EMBL:CAI42640.1 xref: UniProtKB:Q5JTE6 xref: UniProtKB:Q96G48 xref: UniProtKB:Q96HN3 xref: UniProtKB:Q9BWM6 xref: UniProtKB:Q9BZV5 xref: UniProtKB:Q9H9M4 xref: UniProtKB:Q9HAV4 xref: UniProtKB:Q9NT89 xref: UniProtKB:Q9NW39 xref: UniProtKB:Q9ULC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011743 ! XPO5_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018785 ! fadd-exportin-5 physical interaction relationship: participates_in CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:B0037521 name: RAGP1_HUMAN def: "Ran GTPase-activating protein 1" [UniProtKB:P46060] synonym: "RanGAP1" EXACT [UniProtKB:P46060] xref: EMBL:AAH14044.1 xref: EMBL:AAH41396.1 xref: EMBL:BAB47464.1 xref: EMBL:CAA57714.1 xref: EMBL:CAB63073.1 xref: EMBL:CAG30443.1 xref: UniProtKB:P46060 xref: UniProtKB:Q96JJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008079 ! RANGAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0039611 ! RAGP1_HUMAN-Phosphoserine442 relationship: transforms_into CCO:B0043345 ! RAGP1_HUMAN-Phosphothreonine409 [Term] id: CCO:B0037522 name: A2RQD6_HUMAN def: "Bcr-abl1 e6a2 chimeric protein" [UniProtKB:A2RQD6] xref: EMBL:CAM33012.1 xref: UniProtKB:A2RQD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008403 ! BCR-ABL1_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0037556 name: CAZA3_HUMAN def: "F-actin-capping protein subunit alpha-3" [UniProtKB:Q96KX2] synonym: "CapZ alpha-3" EXACT [UniProtKB:Q96KX2] synonym: "CP-alpha-3" EXACT [UniProtKB:Q96KX2] synonym: "Germ cell-specific protein 3" EXACT [UniProtKB:Q96KX2] xref: EMBL:AAH16745.1 xref: EMBL:BAB61901.1 xref: EMBL:BAB71703.1 xref: UniProtKB:Q969J0 xref: UniProtKB:Q96KX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011271 ! CAPZA3_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000542 ! F-actin capping protein complex relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping [Term] id: CCO:B0037567 name: CAZA1_HUMAN def: "F-actin-capping protein subunit alpha-1" [UniProtKB:P52907] synonym: "CapZ alpha-1" EXACT [UniProtKB:P52907] xref: EMBL:AAC00533.1 xref: EMBL:AAH00144.1 xref: EMBL:AAV38171.1 xref: EMBL:BAD96946.1 xref: EMBL:CAG28585.1 xref: EMBL:CAG46618.1 xref: EMBL:CAI14054.1 xref: EMBL:CAI16528.1 xref: UniProtKB:P52907 xref: UniProtKB:Q53FQ6 xref: UniProtKB:Q6FHD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011270 ! CAPZA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016433 ! chuk-capza1 physical interaction relationship: participates_in CCO:I0016495 ! ikbkg-capza1 physical interaction relationship: participates_in CCO:I0016675 ! map3k3-capza1 physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0039340 ! CAZA1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0037573 name: CYFP1_HUMAN def: "Cytoplasmic FMR1-interacting protein 1" [UniProtKB:Q7L576] synonym: "p140sra-1" EXACT [UniProtKB:Q7L576] synonym: "Specifically Rac1-associated protein 1" EXACT [UniProtKB:Q7L576] synonym: "Sra-1" EXACT [UniProtKB:Q7L576] xref: EMBL:AAH01306.2 xref: EMBL:AAH05097.1 xref: EMBL:AAW51476.1 xref: EMBL:AAW51477.1 xref: EMBL:AAW51478.1 xref: EMBL:AAW51479.1 xref: EMBL:BAA07552.1 xref: EMBL:BAC86825.1 xref: UniProtKB:Q14467 xref: UniProtKB:Q5IED0 xref: UniProtKB:Q6ZSX1 xref: UniProtKB:Q7L576 xref: UniProtKB:Q9BSD9 xref: UniProtKB:Q9BVC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011336 ! CYFIP1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007332 ! Rac GTPase binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0064608 ! CYFP1_HUMAN-Phosphotyrosine108 relationship: transforms_into CCO:B0064609 ! CYFP1_HUMAN-Phosphothreonine1068 [Term] id: CCO:B0037580 name: PMM1_HUMAN def: "Phosphomannomutase 1" [UniProtKB:Q92871] synonym: "EC 5.4.2.8" EXACT [UniProtKB:Q92871] synonym: "PMM 1" EXACT [UniProtKB:Q92871] synonym: "PMMH-22" EXACT [UniProtKB:Q92871] xref: EMBL:AAC00023.1 xref: EMBL:AAC51117.1 xref: EMBL:AAH10855.1 xref: EMBL:AAH16818.1 xref: EMBL:BAA13460.1 xref: EMBL:CAB46025.1 xref: EMBL:CAG30430.1 xref: UniProtKB:Q92586 xref: UniProtKB:Q92871 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011621 ! PMM1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000994 ! phosphomannomutase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015282 ! pmm1-rab6a physical interaction [Term] id: CCO:B0037706 name: DNM3A_HUMAN def: "DNA (cytosine-5)-methyltransferase 3A" [UniProtKB:Q9Y6K1] synonym: "DNA methyltransferase HsaIIIA" EXACT [UniProtKB:Q9Y6K1] synonym: "DNA MTase HsaIIIA" EXACT [UniProtKB:Q9Y6K1] synonym: "Dnmt3a" EXACT [UniProtKB:Q9Y6K1] synonym: "EC 2.1.1.37" EXACT [UniProtKB:Q9Y6K1] synonym: "M.HsaIIIA" EXACT [UniProtKB:Q9Y6K1] xref: EMBL:AAD33084.2 xref: EMBL:AAH43617.1 xref: EMBL:AAL57039.1 xref: EMBL:AAN40037.1 xref: EMBL:AAY14761.1 xref: EMBL:EAX00727.1 xref: UniProtKB:Q86XF5 xref: UniProtKB:Q8IZV0 xref: UniProtKB:Q8WXU9 xref: UniProtKB:Q9Y6K1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011359 ! DNMT3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017411 ! setdb1-dnmt3a-1 physical interaction relationship: participates_in CCO:I0017412 ! setdb1-dnmt3a-3 physical interaction relationship: participates_in CCO:I0017521 ! ezh2-dnmt3a physical interaction relationship: participates_in CCO:I0017733 ! dnm3a-ezh2 physical interaction relationship: participates_in CCO:I0018101 ! dnmt3a-setdb1 direct interaction relationship: participates_in CCO:I0018102 ! dnmt3a-setdb1-1 direct interaction relationship: participates_in CCO:I0018103 ! dnmt3a-setdb1-2 direct interaction relationship: participates_in CCO:I0018104 ! dnmt3a-setdb1-3 direct interaction relationship: participates_in CCO:I0019292 ! dnmt3a-ezh2 physical interaction relationship: participates_in CCO:I0019294 ! dnmt1-ezh2-1 physical interaction relationship: participates_in CCO:I0019462 ! setdb1-dnmt3a colocalization relationship: participates_in CCO:P0000646 ! DNA methylation relationship: transforms_into CCO:B0039404 ! DNM3A_HUMAN-Phosphoserine105 [Term] id: CCO:B0037709 name: Q59HC6_HUMAN def: "DNA cytosine methyltransferase 3 alpha isoform a variant" [UniProtKB:Q59HC6] xref: EMBL:BAD92070.1 xref: UniProtKB:Q59HC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0037714 name: DNM3L_HUMAN def: "DNA (cytosine-5)-methyltransferase 3-like" [UniProtKB:Q9UJW3] xref: EMBL:AAF05812.1 xref: EMBL:AAH02560.1 xref: EMBL:BAA95556.1 xref: UniProtKB:Q9BUJ4 xref: UniProtKB:Q9UJW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011360 ! DNMT3L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000310 ! nuclear heterochromatin relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0014989 ! dnmt3l-phpt1 physical interaction relationship: participates_in CCO:I0015481 ! c15orf15-dnmt3l physical interaction relationship: participates_in CCO:I0017391 ! hdac1-dnmt3l direct interaction relationship: participates_in CCO:I0017392 ! hdac1-dnmt3l-1 direct interaction relationship: participates_in CCO:I0017908 ! dnmt3l-hdac1 physical interaction relationship: participates_in CCO:P0000646 ! DNA methylation relationship: participates_in CCO:P0000654 ! genetic imprinting [Term] id: CCO:B0037751 name: BGH3_HUMAN def: "Transforming growth factor-beta-induced protein ig-h3 precursor" [UniProtKB:Q15582] synonym: "Beta ig-h3" EXACT [UniProtKB:Q15582] synonym: "Kerato-epithelin" EXACT [UniProtKB:Q15582] synonym: "RGD-CAP" EXACT [UniProtKB:Q15582] synonym: "RGD-containing collagen-associated protein" EXACT [UniProtKB:Q15582] xref: EMBL:AAA61163.1 xref: EMBL:AAB88695.1 xref: EMBL:AAB88696.1 xref: EMBL:AAB88697.1 xref: EMBL:AAB88698.1 xref: EMBL:AAC08449.1 xref: EMBL:AAC24944.1 xref: EMBL:AAH00097.1 xref: EMBL:AAH04972.1 xref: EMBL:AAN10294.1 xref: UniProtKB:O14471 xref: UniProtKB:O14472 xref: UniProtKB:O14476 xref: UniProtKB:O43216 xref: UniProtKB:O43217 xref: UniProtKB:O43218 xref: UniProtKB:O43219 xref: UniProtKB:Q15582 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011261 ! TGFBI_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0063874 ! BGH3_HUMAN-4-carboxyglutamate108 relationship: transforms_into CCO:B0063875 ! BGH3_HUMAN-4-carboxyglutamate126 relationship: transforms_into CCO:B0063876 ! BGH3_HUMAN-4-carboxyglutamate131 relationship: transforms_into CCO:B0063877 ! BGH3_HUMAN-4-carboxyglutamate133 relationship: transforms_into CCO:B0063878 ! BGH3_HUMAN-4-carboxyglutamate146 relationship: transforms_into CCO:B0063879 ! BGH3_HUMAN-4-carboxyglutamate154 relationship: transforms_into CCO:B0063880 ! BGH3_HUMAN-4-carboxyglutamate166 relationship: transforms_into CCO:B0063881 ! BGH3_HUMAN-4-carboxyglutamate184 relationship: transforms_into CCO:B0063882 ! BGH3_HUMAN-4-carboxyglutamate248 relationship: transforms_into CCO:B0063883 ! BGH3_HUMAN-4-carboxyglutamate250 relationship: transforms_into CCO:B0063884 ! BGH3_HUMAN-4-carboxyglutamate254 relationship: transforms_into CCO:B0063885 ! BGH3_HUMAN-4-carboxyglutamate270 relationship: transforms_into CCO:B0063886 ! BGH3_HUMAN-4-carboxyglutamate283 relationship: transforms_into CCO:B0063887 ! BGH3_HUMAN-4-carboxyglutamate286 relationship: transforms_into CCO:B0063888 ! BGH3_HUMAN-4-carboxyglutamate291 relationship: transforms_into CCO:B0063889 ! BGH3_HUMAN-4-carboxyglutamate301 relationship: transforms_into CCO:B0063890 ! BGH3_HUMAN-4-carboxyglutamate319 relationship: transforms_into CCO:B0063891 ! BGH3_HUMAN-4-carboxyglutamate328 relationship: transforms_into CCO:B0063892 ! BGH3_HUMAN-4-carboxyglutamate331 relationship: transforms_into CCO:B0063893 ! BGH3_HUMAN-4-carboxyglutamate336 relationship: transforms_into CCO:B0063894 ! BGH3_HUMAN-4-carboxyglutamate529 relationship: transforms_into CCO:B0063895 ! BGH3_HUMAN-4-carboxyglutamate534 relationship: transforms_into CCO:B0063896 ! BGH3_HUMAN-4-carboxyglutamate545 relationship: transforms_into CCO:B0063897 ! BGH3_HUMAN-4-carboxyglutamate554 relationship: transforms_into CCO:B0063898 ! BGH3_HUMAN-4-carboxyglutamate564 relationship: transforms_into CCO:B0063899 ! BGH3_HUMAN-4-carboxyglutamate576 relationship: transforms_into CCO:B0063900 ! BGH3_HUMAN-4-carboxyglutamate598 relationship: transforms_into CCO:B0063901 ! BGH3_HUMAN-4-carboxyglutamate611 relationship: transforms_into CCO:B0063902 ! BGH3_HUMAN-4-carboxyglutamate615 [Term] id: CCO:B0037756 name: HABP4_HUMAN def: "Intracellular hyaluronan-binding protein 4" [UniProtKB:Q5JVS0] synonym: "IHABP4" EXACT [UniProtKB:Q5JVS0] synonym: "Ki-1/57 intracellular antigen" EXACT [UniProtKB:Q5JVS0] xref: EMBL:AAC31117.1 xref: EMBL:AAF62546.1 xref: EMBL:AAH18788.1 xref: EMBL:CAI39620.1 xref: EMBL:CAI39621.1 xref: UniProtKB:O75804 xref: UniProtKB:Q5JVS0 xref: UniProtKB:Q8WV33 xref: UniProtKB:Q9NYJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011453 ! HABP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039451 ! HABP4_HUMAN-Phosphothreonine354 relationship: transforms_into CCO:B0039452 ! HABP4_HUMAN-Phosphothreonine375 relationship: transforms_into CCO:B0066744 ! HABP4_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0066745 ! HABP4_HUMAN-Phosphoserine108 [Term] id: CCO:B0037759 name: Q5VU21_HUMAN def: "PAI-1 mRNA-binding protein variant" [UniProtKB:Q5VU21] synonym: "cDNA, FLJ92551, Homo sapiens PAI-1 mRNA-binding protein (PAI-RBP1), mRNA" EXACT [UniProtKB:Q5VU21] synonym: "SERPINE1 mRNA binding protein 1" EXACT [UniProtKB:Q5VU21] xref: EMBL:BAD96675.1 xref: EMBL:BAD96858.1 xref: EMBL:BAG35188.1 xref: EMBL:CAH73325.1 xref: UniProtKB:Q5VU21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0007946 ! SERBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019778 ! rp11_102m16_2-chd3 physical interaction [Term] id: CCO:B0037765 name: OVL2L_HUMAN def: "Putative transcription factor Ovo-like 2-like" [UniProtKB:O00110] xref: EMBL:AAB51180.1 xref: UniProtKB:O00110 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037805 name: ZBT40_HUMAN def: "Zinc finger and BTB domain-containing protein 40" [UniProtKB:Q9NUA8] xref: EMBL:BAA32323.2 xref: EMBL:BAC04518.1 xref: EMBL:CAI22040.1 xref: UniProtKB:O75066 xref: UniProtKB:Q5TFU5 xref: UniProtKB:Q8N1R1 xref: UniProtKB:Q9NUA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011744 ! ZBTB40_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039710 ! ZBT40_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0039711 ! ZBT40_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0039712 ! ZBT40_HUMAN-Phosphoserine703 relationship: transforms_into CCO:B0039713 ! ZBT40_HUMAN-Phosphoserine728 relationship: transforms_into CCO:B0071968 ! ZBT40_HUMAN-Phosphothreonine337 relationship: transforms_into CCO:B0071969 ! ZBT40_HUMAN-Phosphothreonine412 relationship: transforms_into CCO:B0071970 ! ZBT40_HUMAN-Phosphothreonine416 relationship: transforms_into CCO:B0071971 ! ZBT40_HUMAN-Phosphothreonine418 [Term] id: CCO:B0037912 name: CLCN3_HUMAN def: "Chloride channel protein 3" [UniProtKB:P51790] synonym: "ClC-3" EXACT [UniProtKB:P51790] xref: EMBL:AAB95161.1 xref: EMBL:AAD51034.1 xref: EMBL:BAC54560.1 xref: EMBL:CAA55280.1 xref: EMBL:CAA55281.1 xref: UniProtKB:O14918 xref: UniProtKB:P51790 xref: UniProtKB:Q86Z21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011295 ! CLCN3_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001515 ! voltage-gated chloride channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000734 ! vesicle membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: participates_in CCO:I0018285 ! clcn3-slc9a3r1-1 physical interaction [Term] id: CCO:B0037921 name: Q6RCM8_HUMAN def: "Interferon regulatory factor 5 variant 10" [UniProtKB:Q6RCM8] synonym: "Interferon regulatory factor 5 variant 3" EXACT [UniProtKB:Q6RCM8] synonym: "Interferon regulatory factor 5 variant 4" EXACT [UniProtKB:Q6RCM8] xref: EMBL:AAR90325.1 xref: EMBL:AAR90326.1 xref: EMBL:ABB88960.1 xref: UniProtKB:Q6RCM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011492 ! IRF5_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037922 name: A9LSF3_HUMAN def: "IRF-5 variant 12" [UniProtKB:A9LSF3] xref: EMBL:ABX54712.1 xref: UniProtKB:A9LSF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037924 name: IRF5_HUMAN def: "Interferon regulatory factor 5" [UniProtKB:Q13568] synonym: "IRF-5" EXACT [UniProtKB:Q13568] xref: EMBL:AAA96056.1 xref: EMBL:AAH04139.1 xref: EMBL:AAH04201.1 xref: UniProtKB:Q13568 xref: UniProtKB:Q9BQF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011492 ! IRF5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037928 name: IRF7_HUMAN def: "Interferon regulatory factor 7" [UniProtKB:Q92985] synonym: "IRF-7" EXACT [UniProtKB:Q92985] xref: EMBL:AAB17190.1 xref: EMBL:AAB80686.1 xref: EMBL:AAB80688.1 xref: EMBL:AAB80690.1 xref: EMBL:AAB80691.1 xref: EMBL:AAC70999.1 xref: UniProtKB:O00331 xref: UniProtKB:O00332 xref: UniProtKB:O00333 xref: UniProtKB:O75924 xref: UniProtKB:Q92985 xref: UniProtKB:Q9UE79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011494 ! IRF7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039474 ! IRF7_HUMAN-Phosphoserine471 relationship: transforms_into CCO:B0039475 ! IRF7_HUMAN-Phosphoserine472 relationship: transforms_into CCO:B0039476 ! IRF7_HUMAN-Phosphoserine483 relationship: transforms_into CCO:B0039477 ! IRF7_HUMAN-Phosphoserine484 [Term] id: CCO:B0037929 name: IRF8_HUMAN def: "Interferon regulatory factor 8" [UniProtKB:Q02556] synonym: "ICSBP" EXACT [UniProtKB:Q02556] synonym: "Interferon consensus sequence-binding protein" EXACT [UniProtKB:Q02556] synonym: "IRF-8" EXACT [UniProtKB:Q02556] xref: EMBL:AAB63813.1 xref: EMBL:AAI26248.1 xref: UniProtKB:A0AV82 xref: UniProtKB:Q02556 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011495 ! IRF8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037930 name: Q1A7B4_HUMAN def: "Interferon regulatory factor 5 variant 11" [UniProtKB:Q1A7B4] xref: EMBL:ABB88961.1 xref: UniProtKB:Q1A7B4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011492 ! IRF5_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037933 name: Q64GB2_HUMAN def: "Interferon regulatory factor 5 variant 5" [UniProtKB:Q64GB2] synonym: "Interferon regulatory factor 5" EXACT [UniProtKB:Q64GB2] synonym: "Interferon regulatory factor 5, isoform CRA_a" EXACT [UniProtKB:Q64GB2] xref: EMBL:AAU12877.1 xref: EMBL:ABK41901.1 xref: EMBL:EAW83703.1 xref: UniProtKB:Q64GB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011492 ! IRF5_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037934 name: IRF9_HUMAN def: "Interferon regulatory factor 9" [UniProtKB:Q00978] synonym: "IFN-alpha-responsive transcription factor subunit" EXACT [UniProtKB:Q00978] synonym: "Interferon-stimulated gene factor 3 gamma" EXACT [UniProtKB:Q00978] synonym: "IRF-9" EXACT [UniProtKB:Q00978] synonym: "ISGF-3 gamma" EXACT [UniProtKB:Q00978] synonym: "ISGF3 p48 subunit" EXACT [UniProtKB:Q00978] synonym: "Transcriptional regulator ISGF3 subunit gamma" EXACT [UniProtKB:Q00978] xref: EMBL:AAA58687.1 xref: EMBL:AAH35716.1 xref: UniProtKB:Q00978 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011496 ! IRF9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0037936 name: IRF6_HUMAN def: "Interferon regulatory factor 6" [UniProtKB:O14896] synonym: "IRF-6" EXACT [UniProtKB:O14896] xref: EMBL:AAB84111.1 xref: EMBL:AAH14852.1 xref: EMBL:CAA18545.1 xref: UniProtKB:O14896 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011493 ! IRF6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037937 name: A4D1J8_HUMAN def: "Interferon regulatory factor 5" [UniProtKB:A4D1J8] xref: EMBL:EAL24108.1 xref: UniProtKB:A4D1J8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011492 ! IRF5_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037954 name: 7B2_HUMAN def: "Neuroendocrine protein 7B2 precursor" [UniProtKB:P05408] synonym: "Pituitary polypeptide" EXACT [UniProtKB:P05408] synonym: "Secretogranin V" EXACT [UniProtKB:P05408] synonym: "Secretogranin-5" EXACT [UniProtKB:P05408] synonym: "Secretory granule endocrine protein I" EXACT [UniProtKB:P05408] xref: EMBL:AAH05349.1 xref: EMBL:CAA68726.1 xref: EMBL:CAB90397.1 xref: UniProtKB:P01164 xref: UniProtKB:P05408 xref: UniProtKB:Q9BS38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011213 ! SCG5_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000985 ! secretory granule relationship: participates_in CCO:I0017539 ! sgne1-ubqln4-1 physical interaction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0002744 ! regulation of hormone secretion relationship: transforms_into CCO:B0039294 ! 7B2_HUMAN-Phosphoserine205 [Term] id: CCO:B0037974 name: ZNF81_HUMAN def: "Zinc finger protein 81" [UniProtKB:P51508] synonym: "HFZ20" EXACT [UniProtKB:P51508] xref: EMBL:AAS17752.1 xref: EMBL:CAA48148.1 xref: EMBL:CAI39462.1 xref: EMBL:CAI42739.1 xref: EMBL:CAI42943.1 xref: UniProtKB:P51508 xref: UniProtKB:Q6RX22 xref: UniProtKB:Q96QH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011768 ! ZNF81_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037975 name: ZN175_HUMAN def: "Zinc finger protein 175" [UniProtKB:Q9Y473] synonym: "Zinc finger protein OTK18" EXACT [UniProtKB:Q9Y473] xref: EMBL:AAF87843.1 xref: EMBL:AAH52997.1 xref: EMBL:BAA23362.1 xref: UniProtKB:Q9Y473 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011750 ! ZNF175_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037978 name: LIPB2_HUMAN def: "Liprin-beta-2" [UniProtKB:Q8ND30] synonym: "Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2" EXACT [UniProtKB:Q8ND30] synonym: "PTPRF-interacting protein-binding protein 2" EXACT [UniProtKB:Q8ND30] xref: EMBL:AAC26104.1 xref: EMBL:AAH21714.1 xref: EMBL:CAD39087.2 xref: UniProtKB:O75337 xref: UniProtKB:Q8ND30 xref: UniProtKB:Q8WW26 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011514 ! PPFIBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015091 ! ppfibp2-tsg101 physical interaction relationship: transforms_into CCO:B0039484 ! LIPB2_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0039485 ! LIPB2_HUMAN-Phosphoserine512 [Term] id: CCO:B0037981 name: DBX1_HUMAN def: "Homeobox protein DBX1" [UniProtKB:A6NMT0] synonym: "Developing brain homeobox protein 1" EXACT [UniProtKB:A6NMT0] xref: UniProtKB:A6NMT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011341 ! DBX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0037982 name: DLX2_HUMAN def: "Homeobox protein DLX-2" [UniProtKB:Q07687] xref: EMBL:AAA19663.1 xref: EMBL:AAB40902.1 xref: EMBL:AAH32558.1 xref: UniProtKB:Q07687 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011354 ! DLX2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0064785 ! DLX2_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0064786 ! DLX2_HUMAN-Phosphoserine232 [Term] id: CCO:B0037983 name: DLX6_HUMAN def: "Homeobox protein DLX-6" [UniProtKB:P56179] xref: EMBL:AAC17832.1 xref: EMBL:AAH69363.1 xref: EMBL:AAI03689.1 xref: EMBL:AAI03690.1 xref: EMBL:AAI03691.1 xref: EMBL:AAI09382.1 xref: EMBL:EAL24122.1 xref: UniProtKB:A4D1I2 xref: UniProtKB:P56179 xref: UniProtKB:Q3ZAR6 xref: UniProtKB:Q9UPL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011358 ! DLX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0037984 name: DLX4_HUMAN def: "Homeobox protein DLX-4" [UniProtKB:Q92988] synonym: "Beta protein 1" EXACT [UniProtKB:Q92988] synonym: "DLX-7" EXACT [UniProtKB:Q92988] synonym: "DLX-8" EXACT [UniProtKB:Q92988] xref: EMBL:AAC14398.1 xref: EMBL:AAC50942.1 xref: EMBL:AAC51171.1 xref: EMBL:AAG31975.1 xref: EMBL:AAH05812.1 xref: EMBL:AAH14419.1 xref: EMBL:AAH16145.1 xref: EMBL:AAL99503.1 xref: EMBL:AAP35624.1 xref: UniProtKB:O60480 xref: UniProtKB:Q13265 xref: UniProtKB:Q6PJK0 xref: UniProtKB:Q92988 xref: UniProtKB:Q9HBE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011356 ! DLX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0037985 name: BSH_HUMAN def: "Brain-specific homeobox protein homolog" [UniProtKB:Q3C1V8] xref: EMBL:BAE46889.1 xref: UniProtKB:Q3C1V8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011267 ! BSX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0037986 name: Q59HD6_HUMAN def: "Distal-less homeo box 2 variant" [UniProtKB:Q59HD6] xref: EMBL:BAD92060.1 xref: UniProtKB:Q59HD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0037987 name: NKX63_HUMAN def: "Homeobox protein Nkx-6.3" [UniProtKB:A6NJ46] xref: EMBL:BAB71610.1 xref: EMBL:EAW63251.1 xref: EMBL:EAW63252.1 xref: UniProtKB:A6NJ46 xref: UniProtKB:Q96LR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011567 ! NKX6-3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0037988 name: NKX62_HUMAN def: "Homeobox protein Nkx-6.2" [UniProtKB:Q9C056] xref: EMBL:AAI01636.1 xref: EMBL:AAI04824.1 xref: EMBL:AAK13251.1 xref: EMBL:CAI39943.1 xref: EMBL:EAW61308.1 xref: UniProtKB:Q5JSF3 xref: UniProtKB:Q9C056 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011566 ! NKX6-2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0037989 name: DLX5_HUMAN def: "Homeobox protein DLX-5" [UniProtKB:P56178] xref: EMBL:AAC17833.1 xref: EMBL:AAH06226.1 xref: EMBL:BAB14587.1 xref: UniProtKB:P56178 xref: UniProtKB:Q9UPL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011357 ! DLX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation [Term] id: CCO:B0037990 name: DLX3_HUMAN def: "Homeobox protein DLX-3" [UniProtKB:O60479] xref: EMBL:AAC14397.1 xref: EMBL:AAH12361.1 xref: EMBL:AAH28970.1 xref: EMBL:AAL99504.1 xref: UniProtKB:O60479 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011355 ! DLX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0037991 name: NKX61_HUMAN def: "Homeobox protein Nkx-6.1" [UniProtKB:P78426] xref: EMBL:AAD11962.1 xref: UniProtKB:P78426 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011565 ! NKX6-1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002494 ! negative regulation of glial cell differentiation relationship: participates_in CCO:P0002495 ! positive regulation of glial cell differentiation [Term] id: CCO:B0037994 name: RGPS2_HUMAN def: "Ras-specific guanine nucleotide-releasing factor RalGPS2" [UniProtKB:Q86X27] synonym: "Ral GEF with PH domain and SH3-binding motif 2" EXACT [UniProtKB:Q86X27] synonym: "RalA exchange factor RalGPS2" EXACT [UniProtKB:Q86X27] xref: EMBL:AAH47391.1 xref: EMBL:BAA91506.1 xref: EMBL:CAH71096.1 xref: EMBL:CAH71097.1 xref: EMBL:CAH71098.1 xref: EMBL:CAI21918.1 xref: EMBL:CAI21919.1 xref: EMBL:CAI21920.1 xref: EMBL:CAI21925.1 xref: EMBL:EAW91028.1 xref: EMBL:EAW91029.1 xref: UniProtKB:Q5T5Z1 xref: UniProtKB:Q5VZ67 xref: UniProtKB:Q86X27 xref: UniProtKB:Q9NW78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011653 ! RALGPS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0039616 ! RGPS2_HUMAN-Phosphothreonine326 relationship: transforms_into CCO:B0039617 ! RGPS2_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0039618 ! RGPS2_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0043349 ! RGPS2_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0052686 ! RGPS2_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0069919 ! RGPS2_HUMAN-Phosphoserine311 [Term] id: CCO:B0037997 name: Q5JT61_HUMAN def: "Ral GEF with PH domain and SH3 binding motif 1" [UniProtKB:Q5JT61] xref: EMBL:CAI39722.1 xref: EMBL:CAI40642.1 xref: UniProtKB:Q5JT61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011831 ! RALGPS1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0038000 name: Q5JS12_HUMAN def: "Ral GEF with PH domain and SH3 binding motif 1" [UniProtKB:Q5JS12] xref: EMBL:CAI41454.1 xref: UniProtKB:Q5JS12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011831 ! RALGPS1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0038002 name: Q8N7G9_HUMAN def: "cDNA FLJ25604 fis, clone JTH14207" [UniProtKB:Q8N7G9] xref: EMBL:BAC05311.1 xref: UniProtKB:Q8N7G9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0038020 name: ADHX_HUMAN def: "Alcohol dehydrogenase class-3" [UniProtKB:P11766] synonym: "Alcohol dehydrogenase 5" EXACT [UniProtKB:P11766] synonym: "Alcohol dehydrogenase class chi chain" EXACT [UniProtKB:P11766] synonym: "Alcohol dehydrogenase class-III" EXACT [UniProtKB:P11766] synonym: "EC 1.1.1.-" EXACT [UniProtKB:P11766] synonym: "EC 1.1.1.1" EXACT [UniProtKB:P11766] synonym: "EC 1.1.1.284" EXACT [UniProtKB:P11766] synonym: "FALDH" EXACT [UniProtKB:P11766] synonym: "FDH" EXACT [UniProtKB:P11766] synonym: "Glutathione-dependent formaldehyde dehydrogenase" EXACT [UniProtKB:P11766] synonym: "GSH-FDH" EXACT [UniProtKB:P11766] synonym: "S-(hydroxymethyl)glutathione dehydrogenase" EXACT [UniProtKB:P11766] xref: EMBL:AAA51596.1 xref: EMBL:AAA51597.1 xref: EMBL:AAA79018.1 xref: EMBL:AAH14665.1 xref: EMBL:AAV38635.1 xref: EMBL:AAX81412.1 xref: EMBL:CAG46490.1 xref: UniProtKB:P11766 xref: UniProtKB:Q6FHR2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011237 ! ADH5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020222 ! adh5-chd3 physical interaction relationship: transforms_into CCO:B0039306 ! ADHX_HUMAN-N-acetylalanine2 [Term] id: CCO:B0038041 name: A2A2R7_HUMAN def: "Transcription factor AP-2 gamma (Activating enhancer binding protein 2 gamma)" [UniProtKB:A2A2R7] xref: EMBL:CAM28263.1 xref: UniProtKB:A2A2R7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004075 ! TFAP2C_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038042 name: Q96SH0_HUMAN def: "Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha) (Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_a)" [UniProtKB:Q96SH0] xref: EMBL:CAC38371.1 xref: EMBL:EAW55248.1 xref: UniProtKB:Q96SH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004072 ! TFAP2A_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038043 name: AP2E_HUMAN def: "Transcription factor AP-2 epsilon" [UniProtKB:Q6VUC0] synonym: "Activating enhancer-binding protein 2 epsilon" EXACT [UniProtKB:Q6VUC0] synonym: "AP2-epsilon" EXACT [UniProtKB:Q6VUC0] xref: EMBL:AAH41175.1 xref: EMBL:AAQ91614.1 xref: EMBL:CAI23520.1 xref: EMBL:EAX07409.1 xref: UniProtKB:Q6VUC0 xref: UniProtKB:Q8IW12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011247 ! TFAP2E_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039319 ! AP2E_HUMAN-Phosphoserine246 [Term] id: CCO:B0038044 name: AP2D_HUMAN def: "Transcription factor AP-2 delta" [UniProtKB:Q7Z6R9] synonym: "Activating enhancer-binding protein 2 delta" EXACT [UniProtKB:Q7Z6R9] synonym: "AP2-delta" EXACT [UniProtKB:Q7Z6R9] synonym: "Transcription factor AP-2 beta-like 1" EXACT [UniProtKB:Q7Z6R9] xref: EMBL:AAK16926.1 xref: EMBL:CAD92558.1 xref: EMBL:EAX04354.1 xref: UniProtKB:Q7Z6R9 xref: UniProtKB:Q8IWX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011246 ! TFAP2D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039318 ! AP2D_HUMAN-Phosphoserine239 [Term] id: CCO:B0038045 name: Q96SH1_HUMAN def: "Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha) (Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_c)" [UniProtKB:Q96SH1] xref: EMBL:CAC38370.1 xref: EMBL:EAW55250.1 xref: UniProtKB:Q96SH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004072 ! TFAP2A_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038046 name: Q8N1C6_HUMAN def: "Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha)" [UniProtKB:Q8N1C6] xref: EMBL:AAH17754.1 xref: EMBL:CAI20064.1 xref: UniProtKB:Q8N1C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004072 ! TFAP2A_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038047 name: Q5TAV5_HUMAN def: "Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha) (Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_b)" [UniProtKB:Q5TAV5] xref: EMBL:CAI20065.1 xref: EMBL:EAW55249.1 xref: UniProtKB:Q5TAV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004072 ! TFAP2A_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038048 name: A8K557_HUMAN def: "cDNA FLJ78195, highly similar to Homo sapiens transcription factor AP-2 beta (activating enhancer binding protein 2 beta), mRNA" [UniProtKB:A8K557] xref: EMBL:BAF83861.1 xref: UniProtKB:A8K557 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038093 name: ABI3_HUMAN def: "ABI gene family member 3" [UniProtKB:Q9P2A4] synonym: "Nesh" EXACT [UniProtKB:Q9P2A4] synonym: "New molecule including SH3" EXACT [UniProtKB:Q9P2A4] xref: EMBL:AAH07780.1 xref: EMBL:BAA90667.1 xref: EMBL:CAB66644.1 xref: UniProtKB:Q9H0P6 xref: UniProtKB:Q9P2A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011219 ! ABI3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:I0015028 ! abi3-dtnbp1 physical interaction relationship: participates_in CCO:I0015059 ! abi3-runx1t1 physical interaction relationship: participates_in CCO:I0015211 ! abi3-nifie14 physical interaction relationship: participates_in CCO:I0015283 ! abi3-homer1 physical interaction relationship: participates_in CCO:I0015286 ! abi3-snap23 physical interaction relationship: participates_in CCO:I0015369 ! abi3-krt15 physical interaction relationship: participates_in CCO:I0015377 ! abi3-eif3s3 physical interaction relationship: participates_in CCO:I0015672 ! abi3-kiaa0470l physical interaction relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0038095 name: ABI2_HUMAN def: "Abl interactor 2" [UniProtKB:Q9NYB9] synonym: "Abelson interactor 2" EXACT [UniProtKB:Q9NYB9] synonym: "Abi-2" EXACT [UniProtKB:Q9NYB9] synonym: "Abl-binding protein 3" EXACT [UniProtKB:Q9NYB9] synonym: "AblBP3" EXACT [UniProtKB:Q9NYB9] synonym: "Arg-binding protein 1" EXACT [UniProtKB:Q9NYB9] synonym: "ArgBP1" EXACT [UniProtKB:Q9NYB9] xref: EMBL:AAA75446.1 xref: EMBL:AAA92289.1 xref: EMBL:AAF70308.1 xref: EMBL:AAH01439.1 xref: EMBL:AAP88922.1 xref: EMBL:CAA64885.1 xref: UniProtKB:Q13147 xref: UniProtKB:Q13249 xref: UniProtKB:Q13801 xref: UniProtKB:Q9BV70 xref: UniProtKB:Q9NYB9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011218 ! ABI2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004209 ! kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0015068 ! abi2-vcl physical interaction relationship: participates_in CCO:I0015366 ! abi2-nck2 physical interaction relationship: transforms_into CCO:B0039295 ! ABI2_HUMAN-Phosphotyrosine462 relationship: transforms_into CCO:B0065277 ! ABI2_HUMAN-Phosphoserine227 [Term] id: CCO:B0038116 name: MP2K4_HUMAN def: "Dual specificity mitogen-activated protein kinase kinase 4" [UniProtKB:P45985] synonym: "c-Jun N-terminal kinase kinase 1" EXACT [UniProtKB:P45985] synonym: "EC 2.7.12.2" EXACT [UniProtKB:P45985] synonym: "JNK-activating kinase 1" EXACT [UniProtKB:P45985] synonym: "JNKK" EXACT [UniProtKB:P45985] synonym: "MAP kinase kinase 4" EXACT [UniProtKB:P45985] synonym: "SAPK/ERK kinase 1" EXACT [UniProtKB:P45985] synonym: "SEK1" EXACT [UniProtKB:P45985] xref: EMBL:AAC24130.1 xref: EMBL:AAC41719.1 xref: EMBL:AAC50127.1 xref: EMBL:AAV38482.1 xref: EMBL:AAY22176.1 xref: UniProtKB:P45985 xref: UniProtKB:Q5U0B8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011542 ! MAP2K4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0015898 ! map3k1-map2k4-1 physical interaction relationship: participates_in CCO:I0017631 ! npm_alk-pkc physical interaction relationship: participates_in CCO:I0018004 ! map3k1-map2k4-3 physical interaction relationship: participates_in CCO:I0018590 ! map3k1-map2k4-2 phosphorylation relationship: participates_in CCO:I0019243 ! trib1-map2k4-1 physical interaction relationship: participates_in CCO:I0019331 ! map2k4-mapk8-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0068251 ! MP2K4_HUMAN-Phosphoserine90 [Term] id: CCO:B0038128 name: TMED2_HUMAN def: "Transmembrane emp24 domain-containing protein 2 precursor" [UniProtKB:Q15363] synonym: "Membrane protein p24A" EXACT [UniProtKB:Q15363] xref: EMBL:AAH25957.1 xref: EMBL:CAA63069.1 xref: UniProtKB:Q15363 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011713 ! TMED2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001661 ! zymogen granule membrane relationship: participates_in CCO:I0016196 ! tmed10-psen1-4 physical interaction relationship: participates_in CCO:I0018565 ! tmed10-psen1-5 physical interaction [Term] id: CCO:B0038144 name: PSD12_HUMAN def: "26S proteasome non-ATPase regulatory subunit 12" [UniProtKB:O00232] synonym: "26S proteasome regulatory subunit p55" EXACT [UniProtKB:O00232] xref: EMBL:AAH19062.1 xref: EMBL:AAH65826.1 xref: EMBL:BAA19749.1 xref: EMBL:BAD96399.1 xref: UniProtKB:O00232 xref: UniProtKB:Q53HA2 xref: UniProtKB:Q6P053 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011633 ! PSMD12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008717 ! traf6-psmd12 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0039598 ! PSD12_HUMAN-N-acetylalanine2 [Term] id: CCO:B0038151 name: Q59FH9_HUMAN def: "Zinc finger protein 42 isoform 2 variant" [UniProtKB:Q59FH9] xref: EMBL:BAD92718.1 xref: UniProtKB:Q59FH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038152 name: ZN446_HUMAN def: "Zinc finger protein 446" [UniProtKB:Q9NWS9] synonym: "Zinc finger protein with KRAB and SCAN domains 20" EXACT [UniProtKB:Q9NWS9] xref: EMBL:AAQ16304.1 xref: EMBL:BAA91298.1 xref: UniProtKB:Q9NWS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006034 ! ZNF446_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038153 name: Q8NDK2_HUMAN def: "Putative uncharacterized protein DKFZp434K202" [UniProtKB:Q8NDK2] xref: EMBL:CAD38805.1 xref: UniProtKB:Q8NDK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011983 ! DKFZp434K202_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038197 name: PFD3_HUMAN def: "Prefoldin subunit 3" [UniProtKB:P61758] synonym: "HIBBJ46" EXACT [UniProtKB:P61758] synonym: "VBP-1" EXACT [UniProtKB:P61758] synonym: "VHL-binding protein 1" EXACT [UniProtKB:P61758] synonym: "Von Hippel-Lindau-binding protein 1" EXACT [UniProtKB:P61758] xref: EMBL:AAC23907.1 xref: EMBL:AAC50617.1 xref: EMBL:AAH46094.1 xref: EMBL:AAV38411.1 xref: EMBL:CAA76761.1 xref: EMBL:CAI41469.1 xref: UniProtKB:O55228 xref: UniProtKB:P61758 xref: UniProtKB:Q15765 xref: UniProtKB:Q5JT81 xref: UniProtKB:Q86X96 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011600 ! VBP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0016745 ! map3k3-vbp1 physical interaction [Term] id: CCO:B0038202 name: COPA_HUMAN def: "Coatomer subunit alpha" [UniProtKB:P53621] synonym: "Alpha-coat protein" EXACT [UniProtKB:P53621] synonym: "Alpha-COP" EXACT [UniProtKB:P53621] synonym: "HEP-COP" EXACT [UniProtKB:P53621] synonym: "HEPCOP" EXACT [UniProtKB:P53621] xref: EMBL:AAB70879.1 xref: EMBL:AAH38447.1 xref: EMBL:CAI12454.1 xref: EMBL:CAI12455.1 xref: EMBL:CAI15004.1 xref: EMBL:CAI15005.1 xref: EMBL:EAW52723.1 xref: EMBL:EAW52725.1 xref: UniProtKB:P53621 xref: UniProtKB:Q5T201 xref: UniProtKB:Q8IXZ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011309 ! COPA_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000971 ! COPI vesicle coat relationship: participates_in CCO:I0016555 ! ikbkg-copa physical interaction relationship: transforms_into CCO:B0039366 ! COPA_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: transforms_into CCO:B0039368 ! COPA_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0043236 ! COPA_HUMAN-Phosphoserine1035 [Term] id: CCO:B0038221 name: GSTM3_HUMAN def: "Glutathione S-transferase Mu 3" [UniProtKB:P21266] synonym: "EC 2.5.1.18" EXACT [UniProtKB:P21266] synonym: "GST class-mu 3" EXACT [UniProtKB:P21266] synonym: "GSTM3-3" EXACT [UniProtKB:P21266] synonym: "hGSTM3-3" EXACT [UniProtKB:P21266] xref: EMBL:AAA60964.1 xref: EMBL:AAC17866.1 xref: EMBL:AAH00088.1 xref: EMBL:AAH08790.1 xref: EMBL:AAV38748.1 xref: UniProtKB:O60550 xref: UniProtKB:P21266 xref: UniProtKB:Q96HA3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011446 ! GSTM3_human relationship: has_function CCO:F0000783 ! glutathione transferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0038241 name: GSTM1_HUMAN def: "Glutathione S-transferase Mu 1" [UniProtKB:P09488] synonym: "EC 2.5.1.18" EXACT [UniProtKB:P09488] synonym: "GST class-mu 1" EXACT [UniProtKB:P09488] synonym: "GSTM1-1" EXACT [UniProtKB:P09488] synonym: "GSTM1a-1a" EXACT [UniProtKB:P09488] synonym: "GSTM1b-1b" EXACT [UniProtKB:P09488] synonym: "GTH4" EXACT [UniProtKB:P09488] synonym: "HB subunit 4" EXACT [UniProtKB:P09488] xref: EMBL:AAA59203.1 xref: EMBL:AAR85979.1 xref: EMBL:AAT06767.1 xref: EMBL:CAA30821.1 xref: EMBL:CAA35817.1 xref: EMBL:CAA48636.1 xref: EMBL:CAG46666.1 xref: UniProtKB:P09488 xref: UniProtKB:Q5GHG0 xref: UniProtKB:Q6FH88 xref: UniProtKB:Q9UC96 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011444 ! GSTM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0039447 ! GSTM1_HUMAN-Phosphotyrosine23 relationship: transforms_into CCO:B0039448 ! GSTM1_HUMAN-Phosphotyrosine33 relationship: transforms_into CCO:B0039449 ! GSTM1_HUMAN-Phosphothreonine34 [Term] id: CCO:B0038243 name: K1967_HUMAN def: "Protein KIAA1967" [UniProtKB:Q8N163] synonym: "DBC-1" EXACT [UniProtKB:Q8N163] synonym: "DBC.1" EXACT [UniProtKB:Q8N163] synonym: "Deleted in breast cancer gene 1 protein" EXACT [UniProtKB:Q8N163] synonym: "p30 DBC" EXACT [UniProtKB:Q8N163] xref: EMBL:AAG02472.1 xref: EMBL:AAH18269.1 xref: EMBL:AAH65495.1 xref: EMBL:BAB14163.1 xref: EMBL:BAB85553.1 xref: EMBL:BAC04814.1 xref: EMBL:CAB70788.3 xref: EMBL:CAD38866.1 xref: EMBL:CAD39016.1 xref: EMBL:CAD39017.1 xref: EMBL:CAE45976.1 xref: EMBL:EAW63658.1 xref: UniProtKB:A6NL03 xref: UniProtKB:Q6P0Q9 xref: UniProtKB:Q8N163 xref: UniProtKB:Q8N3G7 xref: UniProtKB:Q8N8M1 xref: UniProtKB:Q8TF34 xref: UniProtKB:Q9H9Q9 xref: UniProtKB:Q9HD12 xref: UniProtKB:Q9NT55 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011500 ! KIAA1967_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016409 ! nfkbib-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016731 ! map3k3-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016814 ! nfkb2-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016879 ! relb-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0016953 ! q9nyj8-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0017077 ! tradd-dkfzp761m0817 physical interaction relationship: participates_in CCO:I0017211 ! ikbkb-dkfzp761m0817 physical interaction relationship: transforms_into CCO:B0039478 ! K1967_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0039479 ! K1967_HUMAN-Phosphothreonine454 relationship: transforms_into CCO:B0039480 ! K1967_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0039481 ! K1967_HUMAN-Phosphoserine678 relationship: transforms_into CCO:B0039482 ! K1967_HUMAN-Phosphoserine681 [Term] id: CCO:B0038258 name: ADA1A_HUMAN def: "Alpha-1A adrenergic receptor" [UniProtKB:P35348] synonym: "Alpha 1A-adrenoceptor" EXACT [UniProtKB:P35348] synonym: "Alpha 1A-adrenoreceptor" EXACT [UniProtKB:P35348] synonym: "Alpha-1C adrenergic receptor" EXACT [UniProtKB:P35348] synonym: "Alpha-adrenergic receptor 1c" EXACT [UniProtKB:P35348] xref: EMBL:AAA93114.1 xref: EMBL:AAB59486.1 xref: EMBL:AAB60353.1 xref: EMBL:AAC06138.1 xref: EMBL:AAQ91331.1 xref: EMBL:AAR84644.1 xref: EMBL:AAR84645.1 xref: EMBL:AAR84646.1 xref: EMBL:AAR84647.1 xref: EMBL:AAR84648.1 xref: EMBL:AAR84649.1 xref: EMBL:AAR84650.1 xref: EMBL:BAA04960.1 xref: EMBL:BAA06900.1 xref: EMBL:BAA06901.1 xref: EMBL:BAC05926.1 xref: UniProtKB:O60451 xref: UniProtKB:P35348 xref: UniProtKB:Q13675 xref: UniProtKB:Q13729 xref: UniProtKB:Q6RUJ4 xref: UniProtKB:Q6RUJ5 xref: UniProtKB:Q6RUJ7 xref: UniProtKB:Q6RUJ8 xref: UniProtKB:Q6RUJ9 xref: UniProtKB:Q9UD63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011225 ! ADRA1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015910 ! adra1a-bmp1-1 physical interaction relationship: participates_in CCO:I0015911 ! adra1a-abr-1 physical interaction relationship: participates_in CCO:I0015912 ! adra1a-fnlc-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0039298 ! ADA1A_HUMAN-Phosphoserine215 [Term] id: CCO:B0038260 name: 5HT2C_HUMAN def: "5-hydroxytryptamine receptor 2C" [UniProtKB:P28335] synonym: "5-HT-2C" EXACT [UniProtKB:P28335] synonym: "5-HT2C" EXACT [UniProtKB:P28335] synonym: "5-HTR2C" EXACT [UniProtKB:P28335] synonym: "5HT-1C" EXACT [UniProtKB:P28335] synonym: "Serotonin receptor 2C" EXACT [UniProtKB:P28335] xref: EMBL:AAA60317.1 xref: EMBL:AAB40898.1 xref: EMBL:AAC71658.1 xref: EMBL:AAF35842.1 xref: EMBL:AAH95543.1 xref: EMBL:AAM21130.1 xref: EMBL:CAB59978.1 xref: EMBL:CAH70193.1 xref: EMBL:CAI41335.1 xref: UniProtKB:P28335 xref: UniProtKB:Q5VUF8 xref: UniProtKB:Q9NP28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011212 ! HTR2C_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0038261 name: Q7Z5R9_HUMAN def: "HRH2 protein" [UniProtKB:Q7Z5R9] xref: EMBL:AAH54510.1 xref: UniProtKB:Q7Z5R9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0038262 name: HRH2_HUMAN def: "Histamine H2 receptor" [UniProtKB:P25021] synonym: "Gastric receptor I" EXACT [UniProtKB:P25021] synonym: "H2R" EXACT [UniProtKB:P25021] xref: EMBL:AAA58647.1 xref: EMBL:AAN01270.1 xref: EMBL:BAA08618.1 xref: EMBL:BAA84279.1 xref: EMBL:BAA94469.1 xref: EMBL:CAA66832.1 xref: UniProtKB:P25021 xref: UniProtKB:Q14464 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011463 ! HRH2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0038263 name: ADA1B_HUMAN def: "Alpha-1B adrenergic receptor" [UniProtKB:P35368] synonym: "Alpha 1B-adrenoceptor" EXACT [UniProtKB:P35368] synonym: "Alpha 1B-adrenoreceptor" EXACT [UniProtKB:P35368] xref: EMBL:AAB59485.1 xref: EMBL:AAB60352.1 xref: UniProtKB:P35368 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011226 ! ADRA1B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001279 ! alpha1-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000050 ! integral to membrane of membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017677 ! adra1b-fnlc-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002566 ! negative regulation of glycogen catabolic process relationship: participates_in CCO:P0002567 ! positive regulation of glycogen catabolic process relationship: transforms_into CCO:B0039299 ! ADA1B_HUMAN-Phosphothreonine264 relationship: transforms_into CCO:B0039300 ! ADA1B_HUMAN-Phosphoserine267 [Term] id: CCO:B0038265 name: ADA1D_HUMAN def: "Alpha-1D adrenergic receptor" [UniProtKB:P25100] synonym: "Alpha 1D-adrenoceptor" EXACT [UniProtKB:P25100] synonym: "Alpha 1D-adrenoreceptor" EXACT [UniProtKB:P25100] synonym: "Alpha-1A adrenergic receptor" EXACT [UniProtKB:P25100] synonym: "Alpha-adrenergic receptor 1a" EXACT [UniProtKB:P25100] xref: EMBL:AAA35496.1 xref: EMBL:AAB31163.2 xref: EMBL:AAB59487.1 xref: EMBL:AAB60351.1 xref: EMBL:BAA06222.1 xref: EMBL:CAC00601.2 xref: UniProtKB:P25100 xref: UniProtKB:Q9NPY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011227 ! ADRA1D_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001279 ! alpha1-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017758 ! adra1d-fnlc-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0038266 name: 5HT1D_HUMAN def: "5-hydroxytryptamine receptor 1D" [UniProtKB:P28221] synonym: "5-HT-1D" EXACT [UniProtKB:P28221] synonym: "5-HT-1D-alpha" EXACT [UniProtKB:P28221] synonym: "Serotonin receptor 1D" EXACT [UniProtKB:P28221] xref: EMBL:AAA35491.1 xref: EMBL:AAA60315.1 xref: EMBL:AAH07720.1 xref: EMBL:AAM21126.1 xref: EMBL:AAP35673.1 xref: EMBL:CAB81617.1 xref: UniProtKB:P28221 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011211 ! HTR1D_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0038267 name: ADA2B_HUMAN def: "Alpha-2B adrenergic receptor" [UniProtKB:P18089] synonym: "Alpha-2 adrenergic receptor subtype C2" EXACT [UniProtKB:P18089] synonym: "Alpha-2B adrenoceptor" EXACT [UniProtKB:P18089] synonym: "Alpha-2B adrenoreceptor" EXACT [UniProtKB:P18089] xref: EMBL:AAA51666.1 xref: EMBL:AAA62823.1 xref: EMBL:AAB62558.1 xref: EMBL:AAK01635.1 xref: EMBL:AAS55646.1 xref: EMBL:AAX93218.1 xref: EMBL:AAY43127.1 xref: UniProtKB:P18089 xref: UniProtKB:Q4TUH9 xref: UniProtKB:Q53RF2 xref: UniProtKB:Q9BZK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011233 ! ADRA2B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001280 ! alpha2-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0038294 name: BRPF1_HUMAN def: "Peregrin" [UniProtKB:P55201] synonym: "BR140 protein" EXACT [UniProtKB:P55201] synonym: "Bromodomain and PHD finger-containing protein 1" EXACT [UniProtKB:P55201] xref: EMBL:AAB02119.1 xref: EMBL:AAF19605.1 xref: UniProtKB:P55201 xref: UniProtKB:Q9UHI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011264 ! BRPF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039329 ! BRPF1_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0039330 ! BRPF1_HUMAN-Phosphoserine460 relationship: transforms_into CCO:B0039331 ! BRPF1_HUMAN-Phosphoserine462 relationship: transforms_into CCO:B0039332 ! BRPF1_HUMAN-Phosphoserine922 relationship: transforms_into CCO:B0063990 ! BRPF1_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0063991 ! BRPF1_HUMAN-Phosphoserine1187 [Term] id: CCO:B0038317 name: TAF13_HUMAN def: "Transcription initiation factor TFIID subunit 13" [UniProtKB:Q15543] synonym: "TAF(II)18" EXACT [UniProtKB:Q15543] synonym: "TAFII-18" EXACT [UniProtKB:Q15543] synonym: "TAFII18" EXACT [UniProtKB:Q15543] synonym: "Transcription initiation factor TFIID 18 kDa subunit" EXACT [UniProtKB:Q15543] xref: EMBL:AAI21181.1 xref: EMBL:CAA58827.1 xref: EMBL:CAH71330.1 xref: UniProtKB:Q15543 xref: UniProtKB:Q5TYV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011704 ! TAF13_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:I0018112 ! taf11-taf13-3 direct interaction relationship: participates_in CCO:I0018113 ! taf11-taf13-4 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038370 name: IKZF3_HUMAN def: "Zinc finger protein Aiolos" [UniProtKB:Q9UKT9] synonym: "Ikaros family zinc finger protein 3" EXACT [UniProtKB:Q9UKT9] xref: EMBL:AAF13493.1 xref: EMBL:AAH32707.1 xref: EMBL:CAC80427.1 xref: EMBL:CAC80428.1 xref: EMBL:CAC80429.1 xref: EMBL:CAC80430.1 xref: EMBL:CAC80431.1 xref: EMBL:EAW60606.1 xref: UniProtKB:Q8N574 xref: UniProtKB:Q8WWQ9 xref: UniProtKB:Q8WWR0 xref: UniProtKB:Q8WWR1 xref: UniProtKB:Q8WWR2 xref: UniProtKB:Q8WWR3 xref: UniProtKB:Q9UKT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006024 ! IKZF3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0052448 ! IKZF3_HUMAN-Phosphotyrosine286 relationship: transforms_into CCO:B0052449 ! IKZF3_HUMAN-Phosphotyrosine290 relationship: transforms_into CCO:B0067071 ! IKZF3_HUMAN-Phosphothreonine169 [Term] id: CCO:B0038385 name: RPGF1_HUMAN def: "Rap guanine nucleotide exchange factor 1" [UniProtKB:Q13905] synonym: "C3G protein" EXACT [UniProtKB:Q13905] synonym: "CRK SH3-binding GNRP" EXACT [UniProtKB:Q13905] synonym: "Guanine nucleotide-releasing factor 2" EXACT [UniProtKB:Q13905] xref: EMBL:BAA04770.1 xref: EMBL:CAI13382.1 xref: EMBL:CAI40646.1 xref: UniProtKB:Q13905 xref: UniProtKB:Q5JUE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0039640 ! RPGF1_HUMAN-Phosphoserine360 [Term] id: CCO:B0038386 name: Q5JUE5_HUMAN def: "Rap guanine nucleotide exchange factor (GEF) 1" [UniProtKB:Q5JUE5] xref: EMBL:CAI13381.1 xref: EMBL:CAI40645.1 xref: UniProtKB:Q5JUE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0038390 name: Q5JUE9_HUMAN def: "Rap guanine nucleotide exchange factor (GEF) 1" [UniProtKB:Q5JUE9] xref: EMBL:CAI13384.1 xref: EMBL:CAI40648.1 xref: UniProtKB:Q5JUE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0038391 name: Q8IV73_HUMAN def: "Rap guanine nucleotide exchange factor (GEF) 1" [UniProtKB:Q8IV73] xref: EMBL:AAH41710.1 xref: UniProtKB:Q8IV73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0038407 name: MD12L_HUMAN def: "Mediator of RNA polymerase II transcription subunit 12-like protein" [UniProtKB:Q86YW9] synonym: "Mediator complex subunit 12-like protein" EXACT [UniProtKB:Q86YW9] synonym: "Thyroid hormone receptor-associated-like protein" EXACT [UniProtKB:Q86YW9] synonym: "Trinucleotide repeat-containing gene 11 protein-like" EXACT [UniProtKB:Q86YW9] xref: EMBL:AAF24035.1 xref: EMBL:AAL09579.1 xref: EMBL:AAL09580.1 xref: EMBL:AAO38813.1 xref: EMBL:BAB13461.1 xref: EMBL:BAB14198.1 xref: EMBL:EAW78800.1 xref: UniProtKB:Q86YW9 xref: UniProtKB:Q96PC7 xref: UniProtKB:Q96PC8 xref: UniProtKB:Q9H9M5 xref: UniProtKB:Q9HCD7 xref: UniProtKB:Q9UI69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011531 ! MED12L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068073 ! MD12L_HUMAN-Phosphothreonine462 relationship: transforms_into CCO:B0068074 ! MD12L_HUMAN-Phosphothreonine474 relationship: transforms_into CCO:B0068075 ! MD12L_HUMAN-Phosphotyrosine484 relationship: transforms_into CCO:B0068076 ! MD12L_HUMAN-Phosphoserine1751 [Term] id: CCO:B0038425 name: FOXI2_HUMAN def: "Forkhead box protein I2" [UniProtKB:Q6ZQN5] xref: EMBL:BAC87649.1 xref: UniProtKB:Q6ZQN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011389 ! FOXI2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038434 name: RB11B_HUMAN def: "Ras-related protein Rab-11B" [UniProtKB:Q15907] synonym: "GTP-binding protein YPT3" EXACT [UniProtKB:Q15907] xref: EMBL:AAI10082.1 xref: EMBL:AAM21095.1 xref: EMBL:AAV38343.1 xref: EMBL:CAA56176.1 xref: UniProtKB:Q15907 xref: UniProtKB:Q2YDT2 xref: UniProtKB:Q8NI07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011648 ! RAB11B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020417 ! rab11b-srebf2 physical interaction relationship: participates_in CCO:I0020637 ! rab11b-olfm2 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0039613 ! RB11B_HUMAN-N-acetylglycine2 [Term] id: CCO:B0038438 name: RB11A_HUMAN def: "Ras-related protein Rab-11A" [UniProtKB:P62491] synonym: "Rab-11" EXACT [UniProtKB:P62491] synonym: "YL8" EXACT [UniProtKB:P62491] xref: EMBL:AAC32887.1 xref: EMBL:AAH13348.1 xref: EMBL:AAM21094.1 xref: EMBL:AAV38953.1 xref: EMBL:AAV38956.1 xref: EMBL:CAA37300.1 xref: EMBL:CAA40064.1 xref: EMBL:CAG28597.1 xref: EMBL:CAG38732.1 xref: UniProtKB:P24410 xref: UniProtKB:P62491 xref: UniProtKB:Q5TZN9 xref: UniProtKB:Q9JLX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011647 ! RAB11A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002023 ! recycling endosome membrane relationship: participates_in CCO:I0015164 ! rab11a-rab3il1 physical interaction relationship: participates_in CCO:I0017444 ! dtnbp1-rab11a physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0039612 ! RB11A_HUMAN-N-acetylglycine2 [Term] id: CCO:B0038468 name: CPVL_HUMAN def: "Probable serine carboxypeptidase CPVL precursor" [UniProtKB:Q9H3G5] synonym: "Carboxypeptidase, vitellogenic-like" EXACT [UniProtKB:Q9H3G5] synonym: "EC 3.4.16.-" EXACT [UniProtKB:Q9H3G5] synonym: "HVLP" EXACT [UniProtKB:Q9H3G5] synonym: "VCP-like protein" EXACT [UniProtKB:Q9H3G5] synonym: "Vitellogenic carboxypeptidase-like protein" EXACT [UniProtKB:Q9H3G5] xref: EMBL:AAG14348.1 xref: EMBL:AAG37991.2 xref: EMBL:AAH16838.1 xref: EMBL:AAQ88913.1 xref: EMBL:BAC11618.1 xref: UniProtKB:Q6UX20 xref: UniProtKB:Q8NBL7 xref: UniProtKB:Q96AR7 xref: UniProtKB:Q9H3G5 xref: UniProtKB:Q9HB41 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011324 ! CPVL_human relationship: has_function CCO:F0000649 ! carboxypeptidase activity relationship: has_function CCO:F0000654 ! serine carboxypeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016763 ! map3k3-cpvl physical interaction [Term] id: CCO:B0038544 name: M3K9_HUMAN def: "Mitogen-activated protein kinase kinase kinase 9" [UniProtKB:P80192] synonym: "EC 2.7.11.25" EXACT [UniProtKB:P80192] synonym: "Mixed lineage kinase 1" EXACT [UniProtKB:P80192] xref: EMBL:AAG44591.1 xref: EMBL:AAI11408.1 xref: EMBL:AAQ23054.1 xref: UniProtKB:P80192 xref: UniProtKB:Q0D2G7 xref: UniProtKB:Q6EH31 xref: UniProtKB:Q9H2N5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011522 ! MAP3K9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: transforms_into CCO:B0039493 ! M3K9_HUMAN-Phosphothreonine304 relationship: transforms_into CCO:B0039494 ! M3K9_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0039495 ! M3K9_HUMAN-Phosphothreonine312 relationship: transforms_into CCO:B0039496 ! M3K9_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0039497 ! M3K9_HUMAN-Phosphoserine931 relationship: transforms_into CCO:B0039498 ! M3K9_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0039499 ! M3K9_HUMAN-Phosphoserine998 [Term] id: CCO:B0038558 name: ADA22_HUMAN def: "ADAM 22 precursor" [UniProtKB:Q9P0K1] synonym: "A disintegrin and metalloproteinase domain 22" EXACT [UniProtKB:Q9P0K1] synonym: "Metalloproteinase-disintegrin ADAM22-3" EXACT [UniProtKB:Q9P0K1] synonym: "Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2" EXACT [UniProtKB:Q9P0K1] xref: EMBL:AAD55251.1 xref: EMBL:AAF22476.2 xref: EMBL:AAF73288.1 xref: EMBL:AAF73289.1 xref: EMBL:BAA32349.1 xref: EMBL:BAA32350.1 xref: UniProtKB:O75075 xref: UniProtKB:O75076 xref: UniProtKB:Q9P0K1 xref: UniProtKB:Q9P0K2 xref: UniProtKB:Q9UIA1 xref: UniProtKB:Q9UKK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011230 ! ADAM22_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: transforms_into CCO:B0039301 ! ADA22_HUMAN-Phosphoserine834 relationship: transforms_into CCO:B0039302 ! ADA22_HUMAN-Phosphoserine866 relationship: transforms_into CCO:B0039303 ! ADA22_HUMAN-Phosphoserine868 [Term] id: CCO:B0038563 name: ADA11_HUMAN def: "ADAM 11 precursor" [UniProtKB:O75078] synonym: "A disintegrin and metalloproteinase domain 11" EXACT [UniProtKB:O75078] synonym: "MDC" EXACT [UniProtKB:O75078] synonym: "Metalloproteinase-like, disintegrin-like, and cysteine-rich protein" EXACT [UniProtKB:O75078] xref: EMBL:BAA04213.1 xref: EMBL:BAA06670.1 xref: EMBL:BAA06671.1 xref: EMBL:BAA32352.1 xref: UniProtKB:O75078 xref: UniProtKB:Q14808 xref: UniProtKB:Q14809 xref: UniProtKB:Q14810 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011224 ! ADAM11_human relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020221 ! adam11-stc2 physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0038579 name: CBPZ_HUMAN def: "Carboxypeptidase Z precursor" [UniProtKB:Q66K79] synonym: "CPZ" EXACT [UniProtKB:Q66K79] synonym: "EC 3.4.17.-" EXACT [UniProtKB:Q66K79] xref: EMBL:AAB58911.1 xref: EMBL:AAH80539.1 xref: EMBL:BAB71147.1 xref: UniProtKB:O00520 xref: UniProtKB:Q66K79 xref: UniProtKB:Q96MX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011273 ! CPZ_human relationship: has_function CCO:F0000649 ! carboxypeptidase activity relationship: has_function CCO:F0000650 ! metallocarboxypeptidase activity relationship: has_function CCO:F0000651 ! carboxypeptidase A activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0038585 name: Q7L3E5_HUMAN def: "HDAC6 protein" [UniProtKB:Q7L3E5] synonym: "Histone deacetylase 6, isoform CRA_d" EXACT [UniProtKB:Q7L3E5] xref: EMBL:AAH13737.1 xref: EMBL:EAW50748.1 xref: UniProtKB:Q7L3E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004791 ! HDAC6_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038587 name: Q6ZSV8_HUMAN xref: UniProtKB:Q6ZSV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003359 ! hydrolase activity relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038590 name: Q6IFJ9_HUMAN def: "Olfactory receptor OR14-37" [UniProtKB:Q6IFJ9] xref: EMBL:DAA04661.1 xref: UniProtKB:Q6IFJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0038591 name: Q8NG79_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NG79] xref: EMBL:BAC06170.1 xref: UniProtKB:Q8NG79 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0038592 name: OR6M1_HUMAN def: "Olfactory receptor 6M1" [UniProtKB:Q8NGM8] synonym: "Olfactory receptor OR11-271" EXACT [UniProtKB:Q8NGM8] xref: EMBL:AAK95091.1 xref: EMBL:BAC05982.1 xref: EMBL:DAA04891.1 xref: UniProtKB:Q6IEW9 xref: UniProtKB:Q8NGM8 xref: UniProtKB:Q96R37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011575 ! OR6M1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0038594 name: A6NJJ1_HUMAN def: "Putative uncharacterized protein OR6W1P" [UniProtKB:A6NJJ1] xref: UniProtKB:A6NJJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011806 ! OR6W1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0038614 name: A6NJ87_HUMAN def: "Uncharacterized protein ENSP00000372797" [UniProtKB:A6NJ87] xref: UniProtKB:A6NJ87 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0038625 name: Q96M79_HUMAN def: "cDNA FLJ32768 fis, clone TESTI2001879, weakly similar to ZINC FINGER PROTEIN 157" [UniProtKB:Q96M79] xref: EMBL:BAB71430.1 xref: UniProtKB:Q96M79 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038627 name: ZNF19_HUMAN def: "Zinc finger protein 19" [UniProtKB:P17023] synonym: "Zinc finger protein KOX12" EXACT [UniProtKB:P17023] xref: EMBL:AAA36814.1 xref: EMBL:AAH47091.1 xref: EMBL:CAA36569.1 xref: UniProtKB:P17023 xref: UniProtKB:Q86Y66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011767 ! ZNF19_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038636 name: PLS1_HUMAN def: "Phospholipid scramblase 1" [UniProtKB:O15162] synonym: "Ca(2+)-dependent phospholipid scramblase 1" EXACT [UniProtKB:O15162] synonym: "Erythrocyte phospholipid scramblase" EXACT [UniProtKB:O15162] synonym: "MmTRA1b" EXACT [UniProtKB:O15162] synonym: "PL scramblase 1" EXACT [UniProtKB:O15162] xref: EMBL:AAC99413.1 xref: EMBL:AAF80593.1 xref: EMBL:AAH21100.1 xref: EMBL:AAH32718.1 xref: EMBL:BAA32568.1 xref: UniProtKB:O15162 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011614 ! PLSCR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014982 ! plscr1-rasd1 physical interaction relationship: participates_in CCO:I0014998 ! cry1-plscr1 physical interaction relationship: participates_in CCO:I0015005 ! dtx2-plscr1 physical interaction relationship: participates_in CCO:I0015020 ! hoxa1-plscr1 physical interaction relationship: participates_in CCO:I0015134 ! plscr1-sf1 physical interaction relationship: participates_in CCO:I0015309 ! hoxb6-plscr1 physical interaction relationship: participates_in CCO:I0015327 ! pcqap-plscr1 physical interaction relationship: participates_in CCO:I0015343 ! ihpk2-plscr1 physical interaction relationship: participates_in CCO:I0015566 ! cdc42ep1-plscr1 physical interaction relationship: participates_in CCO:I0015595 ! plscr1-znf581 physical interaction relationship: participates_in CCO:I0015606 ! hoxa9-plscr1 physical interaction relationship: participates_in CCO:I0015624 ! hey2-plscr1 physical interaction relationship: participates_in CCO:I0015705 ! mgc13138-plscr1 physical interaction relationship: participates_in CCO:I0015731 ! ewsr1-plscr1 physical interaction relationship: participates_in CCO:I0015775 ! cntfr-plscr1 physical interaction relationship: participates_in CCO:I0017622 ! rere-plscr1 physical interaction relationship: transforms_into CCO:B0039588 ! PLS1_HUMAN-Phosphotyrosine69 relationship: transforms_into CCO:B0039589 ! PLS1_HUMAN-Phosphotyrosine74 relationship: transforms_into CCO:B0039590 ! PLS1_HUMAN-Phosphothreonine161 [Term] id: CCO:B0038667 name: NAT10_HUMAN def: "N-acetyltransferase 10" [UniProtKB:Q9H0A0] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q9H0A0] xref: EMBL:AAH35558.1 xref: EMBL:AAO49126.1 xref: EMBL:BAA91800.1 xref: EMBL:BAB13995.1 xref: EMBL:BAB21800.1 xref: EMBL:CAB66816.1 xref: UniProtKB:Q86WK5 xref: UniProtKB:Q9C0F4 xref: UniProtKB:Q9H0A0 xref: UniProtKB:Q9HA61 xref: UniProtKB:Q9NVF2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011555 ! NAT10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: transforms_into CCO:B0068444 ! NAT10_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0068445 ! NAT10_HUMAN-Phosphoserine984 relationship: transforms_into CCO:B0068446 ! NAT10_HUMAN-Phosphoserine987 [Term] id: CCO:B0038671 name: REL1_HUMAN def: "Prorelaxin H1 precursor" [UniProtKB:P04808] xref: EMBL:AAD14429.1 xref: EMBL:AAD21967.1 xref: EMBL:AAH05956.1 xref: EMBL:CAA23838.1 xref: EMBL:CAA23839.1 xref: EMBL:CAA25461.1 xref: EMBL:CAC04179.1 xref: UniProtKB:P04808 xref: UniProtKB:Q99936 xref: UniProtKB:Q9UQJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011649 ! RLN1_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0038734 name: DPP4_HUMAN def: "Dipeptidyl peptidase 4" [UniProtKB:P27487] synonym: "ADABP" EXACT [UniProtKB:P27487] synonym: "Adenosine deaminase complexing protein 2" EXACT [UniProtKB:P27487] synonym: "CD26 antigen" EXACT [UniProtKB:P27487] synonym: "Dipeptidyl peptidase IV" EXACT [UniProtKB:P27487] synonym: "DPP IV" EXACT [UniProtKB:P27487] synonym: "EC 3.4.14.5" EXACT [UniProtKB:P27487] synonym: "T-cell activation antigen CD26" EXACT [UniProtKB:P27487] synonym: "TP103" EXACT [UniProtKB:P27487] xref: EMBL:AAA51943.1 xref: EMBL:AAA52308.1 xref: EMBL:AAB35614.1 xref: EMBL:AAB60646.1 xref: EMBL:AAH13329.2 xref: EMBL:AAH65265.1 xref: EMBL:CAA43118.1 xref: UniProtKB:P27487 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011365 ! DPP4_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000704 ! dipeptidyl-peptidase IV activity relationship: has_function CCO:F0000714 ! prolyl oligopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001955 ! intercellular canaliculus relationship: participates_in CCO:P0001848 ! regulation of cell-cell adhesion mediated by integrin [Term] id: CCO:B0038746 name: M3K7_HUMAN def: "Mitogen-activated protein kinase kinase kinase 7" [UniProtKB:O43318] synonym: "EC 2.7.11.25" EXACT [UniProtKB:O43318] synonym: "TGF-beta-activated kinase 1" EXACT [UniProtKB:O43318] synonym: "Transforming growth factor-beta-activated kinase 1" EXACT [UniProtKB:O43318] xref: EMBL:AAH17715.1 xref: EMBL:ABC40734.1 xref: EMBL:BAA25025.1 xref: EMBL:BAA25026.1 xref: EMBL:BAA25027.2 xref: EMBL:CAI19611.1 xref: EMBL:CAI19612.1 xref: EMBL:CAI23532.1 xref: EMBL:CAI23533.1 xref: UniProtKB:O43317 xref: UniProtKB:O43318 xref: UniProtKB:O43319 xref: UniProtKB:Q5TDN2 xref: UniProtKB:Q5TDN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011521 ! MAP3K7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016116 ! traf6-tab1-1 physical interaction relationship: participates_in CCO:I0016117 ! ikk-nik physical interaction relationship: participates_in CCO:I0016118 ! tak1-ikap physical interaction relationship: participates_in CCO:I0017373 ! tak1-stat3-4 physical interaction relationship: participates_in CCO:I0017858 ! peli1-irak1-2 physical interaction relationship: participates_in CCO:I0018057 ! tak1-stat3-2 physical interaction relationship: participates_in CCO:I0018058 ! tak1-stat3-3 physical interaction relationship: participates_in CCO:I0018059 ! tak1-stat3-5 physical interaction relationship: participates_in CCO:I0018060 ! tak1-stat3-6 physical interaction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation relationship: transforms_into CCO:B0039489 ! M3K7_HUMAN-Phosphothreonine184 relationship: transforms_into CCO:B0039490 ! M3K7_HUMAN-Phosphothreonine187 relationship: transforms_into CCO:B0039491 ! M3K7_HUMAN-Phosphoserine192 relationship: transforms_into CCO:B0039492 ! M3K7_HUMAN-Phosphoserine439 [Term] id: CCO:B0038779 name: SYG_HUMAN def: "Glycyl-tRNA synthetase" [UniProtKB:P41250] synonym: "EC 6.1.1.14" EXACT [UniProtKB:P41250] synonym: "Glycine--tRNA ligase" EXACT [UniProtKB:P41250] synonym: "GlyRS" EXACT [UniProtKB:P41250] xref: EMBL:AAA57001.1 xref: EMBL:AAA86443.1 xref: EMBL:AAC71652.1 xref: EMBL:AAH07722.1 xref: EMBL:AAH07755.1 xref: EMBL:BAA06338.1 xref: UniProtKB:P41250 xref: UniProtKB:Q969Y1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011697 ! GARS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020529 ! celsr2-gars physical interaction relationship: transforms_into CCO:B0039662 ! SYG_HUMAN-Phosphotyrosine453 [Term] id: CCO:B0038785 name: ADCK1_HUMAN def: "Uncharacterized aarF domain-containing protein kinase 1 precursor" [UniProtKB:Q86TW2] synonym: "EC 2.7.11.-" EXACT [UniProtKB:Q86TW2] xref: EMBL:AAH58906.1 xref: EMBL:CAD62620.1 xref: UniProtKB:Q6PD65 xref: UniProtKB:Q86TW2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011236 ! ADCK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020419 ! rab1a-q86tw2 physical interaction relationship: transforms_into CCO:B0039305 ! ADCK1_HUMAN-Phosphothreonine441 [Term] id: CCO:B0038837 name: Q569H8_HUMAN def: "ESRRA protein" [UniProtKB:Q569H8] synonym: "Estrogen-related receptor alpha" EXACT [UniProtKB:Q569H8] synonym: "HCG2016877, isoform CRA_b" EXACT [UniProtKB:Q569H8] xref: EMBL:AAH63795.2 xref: EMBL:AAH92470.1 xref: EMBL:AAH93720.1 xref: EMBL:AAH93722.1 xref: EMBL:ABF47104.1 xref: EMBL:EAW74246.1 xref: UniProtKB:Q569H8 xref: UniProtKB:Q6P3W9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011378 ! ESRRA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038838 name: ERR1_HUMAN def: "Steroid hormone receptor ERR1" [UniProtKB:P11474] synonym: "ERR-alpha" EXACT [UniProtKB:P11474] synonym: "Estrogen receptor-like 1" EXACT [UniProtKB:P11474] synonym: "Estrogen-related receptor, alpha" EXACT [UniProtKB:P11474] synonym: "Nuclear receptor subfamily 3 group B member 1" EXACT [UniProtKB:P11474] xref: EMBL:AAB17015.1 xref: EMBL:CAA35778.1 xref: UniProtKB:P11474 xref: UniProtKB:Q14514 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011378 ! ESRRA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018531 ! trrap-err1 direct interaction relationship: participates_in CCO:I0018691 ! err1-trrap-1 physical interaction relationship: participates_in CCO:I0018692 ! err1-trrap-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065135 ! ERR1_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0065136 ! ERR1_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0065137 ! ERR1_HUMAN-Phosphoserine27 [Term] id: CCO:B0038840 name: Q9HCB2_HUMAN def: "HERRB2" [UniProtKB:Q9HCB2] xref: EMBL:AAG29619.1 xref: UniProtKB:Q9HCB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038843 name: ERR2_HUMAN def: "Steroid hormone receptor ERR2" [UniProtKB:O95718] synonym: "ERR beta-2" EXACT [UniProtKB:O95718] synonym: "ERR-beta" EXACT [UniProtKB:O95718] synonym: "Estrogen receptor-like 2" EXACT [UniProtKB:O95718] synonym: "Estrogen-related receptor, beta" EXACT [UniProtKB:O95718] synonym: "Nuclear receptor subfamily 3 group B member 2" EXACT [UniProtKB:O95718] xref: EMBL:AAC99409.1 xref: EMBL:AAG17472.1 xref: UniProtKB:O95718 xref: UniProtKB:Q9HCB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011379 ! ESRRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038845 name: Q5F0P7_HUMAN def: "Estrogen receptor-related receptor beta2-delta-10" [UniProtKB:Q5F0P7] xref: EMBL:AAS15572.1 xref: UniProtKB:Q5F0P7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011379 ! ESRRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0038846 name: ERR3_HUMAN def: "Estrogen-related receptor gamma" [UniProtKB:P62508] synonym: "ERR gamma-2" EXACT [UniProtKB:P62508] synonym: "Estrogen receptor-related protein 3" EXACT [UniProtKB:P62508] synonym: "Nuclear receptor subfamily 3 group B member 3" EXACT [UniProtKB:P62508] xref: EMBL:AAC39899.1 xref: EMBL:AAC99410.1 xref: EMBL:AAD48370.1 xref: EMBL:AAH08218.1 xref: EMBL:AAH64700.1 xref: EMBL:AAQ93376.1 xref: EMBL:AAQ93377.1 xref: EMBL:AAQ93378.1 xref: EMBL:AAQ93379.1 xref: EMBL:AAQ93380.1 xref: EMBL:AAQ93381.1 xref: EMBL:AAS00098.1 xref: EMBL:BAA74855.2 xref: EMBL:CAH18320.1 xref: EMBL:CAH70618.1 xref: EMBL:CAH70619.1 xref: EMBL:CAH71594.1 xref: EMBL:CAH71595.1 xref: UniProtKB:O75454 xref: UniProtKB:O96021 xref: UniProtKB:P62508 xref: UniProtKB:Q68DA0 xref: UniProtKB:Q6P274 xref: UniProtKB:Q6PK28 xref: UniProtKB:Q6TS38 xref: UniProtKB:Q9R1F3 xref: UniProtKB:Q9UNJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011380 ! ESRRG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007991 ! AF-2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0038850 name: NSF_HUMAN def: "Vesicle-fusing ATPase" [UniProtKB:P46459] synonym: "EC 3.6.4.6" EXACT [UniProtKB:P46459] synonym: "N-ethylmaleimide-sensitive fusion protein" EXACT [UniProtKB:P46459] synonym: "NEM-sensitive fusion protein" EXACT [UniProtKB:P46459] synonym: "Vesicular-fusion protein NSF" EXACT [UniProtKB:P46459] xref: EMBL:AAA17411.1 xref: EMBL:AAF04745.2 xref: EMBL:AAF70545.1 xref: EMBL:AAH30613.1 xref: UniProtKB:P46459 xref: UniProtKB:Q8N6D7 xref: UniProtKB:Q9UKZ2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011573 ! NSF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:I0020386 ! nsf-eif3s6 physical interaction relationship: transforms_into CCO:B0039573 ! NSF_HUMAN-Phosphotyrosine259 [Term] id: CCO:B0038854 name: FZD5_HUMAN def: "Frizzled-5 precursor" [UniProtKB:Q13467] synonym: "Fz-5" EXACT [UniProtKB:Q13467] synonym: "FzE5" EXACT [UniProtKB:Q13467] synonym: "hFz5" EXACT [UniProtKB:Q13467] xref: EMBL:AAC50385.1 xref: EMBL:AAY24058.1 xref: EMBL:BAB60959.1 xref: UniProtKB:Q13467 xref: UniProtKB:Q53R22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011409 ! FZD5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0038855 name: FZD1_HUMAN def: "Frizzled-1 precursor" [UniProtKB:Q9UP38] synonym: "Fz-1" EXACT [UniProtKB:Q9UP38] synonym: "FzE1" EXACT [UniProtKB:Q9UP38] synonym: "hFz1" EXACT [UniProtKB:Q9UP38] xref: EMBL:AAD41636.1 xref: EMBL:AAH51271.1 xref: EMBL:AAS02008.1 xref: EMBL:BAA34666.1 xref: UniProtKB:O94815 xref: UniProtKB:Q549T8 xref: UniProtKB:Q9UP38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011407 ! FZD1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0038856 name: FZD7_HUMAN def: "Frizzled-7 precursor" [UniProtKB:O75084] synonym: "Fz-7" EXACT [UniProtKB:O75084] synonym: "FzE3" EXACT [UniProtKB:O75084] synonym: "hFz7" EXACT [UniProtKB:O75084] xref: EMBL:AAH15915.1 xref: EMBL:BAA32424.1 xref: EMBL:BAA34668.1 xref: UniProtKB:O75084 xref: UniProtKB:O94816 xref: UniProtKB:Q96B74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011410 ! FZD7_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015291 ! fzd7-ubqln1 physical interaction relationship: participates_in CCO:I0017530 ! fzd7-ubqln4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0038857 name: FZD2_HUMAN def: "Frizzled-2 precursor" [UniProtKB:Q14332] synonym: "Fz-2" EXACT [UniProtKB:Q14332] synonym: "FzE2" EXACT [UniProtKB:Q14332] synonym: "hFz2" EXACT [UniProtKB:Q14332] xref: EMBL:AAB46397.1 xref: EMBL:AAI13403.1 xref: EMBL:AAI13405.1 xref: EMBL:BAA34667.1 xref: UniProtKB:Q0VG82 xref: UniProtKB:Q14332 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011408 ! FZD2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0038861 name: FZD9_HUMAN def: "Frizzled-9 precursor" [UniProtKB:O00144] synonym: "CD349 antigen" EXACT [UniProtKB:O00144] synonym: "Fz-9" EXACT [UniProtKB:O00144] synonym: "FzE6" EXACT [UniProtKB:O00144] synonym: "hFz9" EXACT [UniProtKB:O00144] xref: EMBL:AAC51174.1 xref: EMBL:AAQ93359.1 xref: UniProtKB:O00144 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011412 ! FZD9_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0038863 name: FZD8_HUMAN def: "Frizzled-8 precursor" [UniProtKB:Q9H461] synonym: "Fz-8" EXACT [UniProtKB:Q9H461] synonym: "hFz8" EXACT [UniProtKB:Q9H461] xref: EMBL:BAB41064.1 xref: EMBL:CAC10185.1 xref: UniProtKB:Q9H461 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011411 ! FZD8_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003594 ! Wnt-protein binding relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0038865 name: FZD10_HUMAN def: "Frizzled-10 precursor" [UniProtKB:Q9ULW2] synonym: "CD350 antigen" EXACT [UniProtKB:Q9ULW2] synonym: "Fz-10" EXACT [UniProtKB:Q9ULW2] synonym: "FzE7" EXACT [UniProtKB:Q9ULW2] synonym: "hFz10" EXACT [UniProtKB:Q9ULW2] xref: EMBL:AAH74997.1 xref: EMBL:AAH74998.1 xref: EMBL:BAA84093.1 xref: UniProtKB:Q9ULW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011406 ! FZD10_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0038866 name: Q8TAN2_HUMAN def: "Frizzled homolog 9 (Drosophila)" [UniProtKB:Q8TAN2] xref: EMBL:AAH26333.1 xref: UniProtKB:Q8TAN2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011412 ! FZD9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014991 ! fzd9-mdfi physical interaction [Term] id: CCO:B0038878 name: CSF1_HUMAN def: "Macrophage colony-stimulating factor 1 precursor" [UniProtKB:P09603] synonym: "CSF-1" EXACT [UniProtKB:P09603] synonym: "Lanimostim" EXACT [UniProtKB:P09603] synonym: "M-CSF" EXACT [UniProtKB:P09603] synonym: "MCSF" EXACT [UniProtKB:P09603] xref: EMBL:AAA52117.1 xref: EMBL:AAA52120.2 xref: EMBL:AAA59572.1 xref: EMBL:AAA59573.1 xref: EMBL:AAA64849.1 xref: EMBL:AAB59527.1 xref: EMBL:AAH21117.1 xref: EMBL:CAA29265.1 xref: EMBL:CAA29479.1 xref: UniProtKB:P09603 xref: UniProtKB:Q13130 xref: UniProtKB:Q14086 xref: UniProtKB:Q14806 xref: UniProtKB:Q9UQR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011330 ! CSF1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001459 ! macrophage colony stimulating factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0038926 name: TRPV4_HUMAN def: "Transient receptor potential cation channel subfamily V member 4" [UniProtKB:Q9HBA0] synonym: "Osm-9-like TRP channel 4" EXACT [UniProtKB:Q9HBA0] synonym: "OTRPC4" EXACT [UniProtKB:Q9HBA0] synonym: "Transient receptor potential protein 12" EXACT [UniProtKB:Q9HBA0] synonym: "TRP12" EXACT [UniProtKB:Q9HBA0] synonym: "TrpV4" EXACT [UniProtKB:Q9HBA0] synonym: "Vanilloid receptor-like channel 2" EXACT [UniProtKB:Q9HBA0] synonym: "Vanilloid receptor-like protein 2" EXACT [UniProtKB:Q9HBA0] synonym: "Vanilloid receptor-related osmotically-activated channel" EXACT [UniProtKB:Q9HBA0] synonym: "VR-OAC" EXACT [UniProtKB:Q9HBA0] synonym: "VRL-2" EXACT [UniProtKB:Q9HBA0] xref: EMBL:AAG16127.1 xref: EMBL:AAG28029.1 xref: EMBL:AAI17427.1 xref: EMBL:AAK69487.1 xref: EMBL:AAZ04918.1 xref: EMBL:AAZ04919.1 xref: EMBL:AAZ04920.1 xref: EMBL:BAB69040.1 xref: EMBL:BAC06573.1 xref: EMBL:BAC55864.1 xref: EMBL:CAC82937.1 xref: UniProtKB:Q17R79 xref: UniProtKB:Q2Y122 xref: UniProtKB:Q2Y123 xref: UniProtKB:Q2Y124 xref: UniProtKB:Q86YZ6 xref: UniProtKB:Q8NDY7 xref: UniProtKB:Q8NG64 xref: UniProtKB:Q96Q92 xref: UniProtKB:Q96RS7 xref: UniProtKB:Q9HBA0 xref: UniProtKB:Q9HBC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011724 ! TRPV4_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001524 ! cation channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000763 ! osmosensory signaling pathway relationship: transforms_into CCO:B0039693 ! TRPV4_HUMAN-Phosphotyrosine253 [Term] id: CCO:B0038932 name: TRPV1_HUMAN def: "Transient receptor potential cation channel subfamily V member 1" [UniProtKB:Q8NER1] synonym: "Capsaicin receptor" EXACT [UniProtKB:Q8NER1] synonym: "Osm-9-like TRP channel 1" EXACT [UniProtKB:Q8NER1] synonym: "OTRPC1" EXACT [UniProtKB:Q8NER1] synonym: "TrpV1" EXACT [UniProtKB:Q8NER1] synonym: "Vanilloid receptor 1" EXACT [UniProtKB:Q8NER1] xref: EMBL:AAG43466.1 xref: EMBL:AAG43467.1 xref: EMBL:AAM89472.1 xref: EMBL:CAB66735.1 xref: EMBL:CAB89866.2 xref: EMBL:CAB95729.1 xref: UniProtKB:Q8NER1 xref: UniProtKB:Q9H0G9 xref: UniProtKB:Q9H303 xref: UniProtKB:Q9H304 xref: UniProtKB:Q9NQ74 xref: UniProtKB:Q9NY22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011721 ! TRPV1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0039682 ! TRPV1_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0039683 ! TRPV1_HUMAN-Phosphothreonine145 relationship: transforms_into CCO:B0039684 ! TRPV1_HUMAN-Phosphothreonine371 relationship: transforms_into CCO:B0039685 ! TRPV1_HUMAN-Phosphoserine502 relationship: transforms_into CCO:B0039686 ! TRPV1_HUMAN-Phosphothreonine705 relationship: transforms_into CCO:B0039687 ! TRPV1_HUMAN-Phosphoserine775 relationship: transforms_into CCO:B0039688 ! TRPV1_HUMAN-Phosphoserine801 relationship: transforms_into CCO:B0039689 ! TRPV1_HUMAN-Phosphoserine821 [Term] id: CCO:B0038937 name: FA96B_HUMAN def: "UPF0195 protein FAM96B" [UniProtKB:Q9Y3D0] xref: EMBL:AAD34123.1 xref: EMBL:AAF29082.1 xref: EMBL:AAH01733.1 xref: EMBL:AAH05023.1 xref: UniProtKB:Q9Y3D0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011385 ! FAM96B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015089 ! cgi_128-wdr39 physical interaction [Term] id: CCO:B0038963 name: CCL7_HUMAN def: "C-C motif chemokine 7 precursor" [UniProtKB:P80098] synonym: "MCP-3" EXACT [UniProtKB:P80098] synonym: "Monocyte chemoattractant protein 3" EXACT [UniProtKB:P80098] synonym: "Monocyte chemotactic protein 3" EXACT [UniProtKB:P80098] synonym: "NC28" EXACT [UniProtKB:P80098] synonym: "Small-inducible cytokine A7" EXACT [UniProtKB:P80098] xref: EMBL:AAC03538.1 xref: EMBL:AAH92436.1 xref: EMBL:AAI12259.1 xref: EMBL:AAI12261.1 xref: EMBL:CAA50405.1 xref: EMBL:CAA50406.1 xref: EMBL:CAA50407.1 xref: EMBL:CAA51055.1 xref: UniProtKB:P80098 xref: UniProtKB:Q569J6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011284 ! CCL7_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0020269 ! ccl7-fez1 physical interaction relationship: participates_in CCO:I0020503 ! aes-ccl7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039350 ! CCL7_HUMAN-Pyrrolidone carboxylic acid24 [Term] id: CCO:B0038965 name: CCL2_HUMAN def: "C-C motif chemokine 2 precursor" [UniProtKB:P13500] synonym: "HC11" EXACT [UniProtKB:P13500] synonym: "MCAF" EXACT [UniProtKB:P13500] synonym: "MCP-1" EXACT [UniProtKB:P13500] synonym: "Monocyte chemoattractant protein 1" EXACT [UniProtKB:P13500] synonym: "Monocyte chemotactic and activating factor" EXACT [UniProtKB:P13500] synonym: "Monocyte chemotactic protein 1" EXACT [UniProtKB:P13500] synonym: "Monocyte secretory protein JE" EXACT [UniProtKB:P13500] synonym: "Small-inducible cytokine A2" EXACT [UniProtKB:P13500] xref: EMBL:AAA18102.1 xref: EMBL:AAA18164.1 xref: EMBL:AAA36330.1 xref: EMBL:AAA60308.1 xref: EMBL:AAA60309.1 xref: EMBL:AAB20651.1 xref: EMBL:AAB29926.1 xref: EMBL:AAH09716.1 xref: EMBL:AAM54046.1 xref: EMBL:AAP35993.1 xref: EMBL:CAA01352.1 xref: EMBL:CAA32876.1 xref: EMBL:CAC14049.1 xref: UniProtKB:P13500 xref: UniProtKB:Q9UDF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011283 ! CCL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: transforms_into CCO:B0039349 ! CCL2_HUMAN-Pyrrolidone carboxylic acid24 [Term] id: CCO:B0038966 name: CCL13_HUMAN def: "C-C motif chemokine 13 precursor" [UniProtKB:Q99616] synonym: "CK-beta-10" EXACT [UniProtKB:Q99616] synonym: "MCP-4" EXACT [UniProtKB:Q99616] synonym: "Monocyte chemoattractant protein 4" EXACT [UniProtKB:Q99616] synonym: "Monocyte chemotactic protein 4" EXACT [UniProtKB:Q99616] synonym: "NCC-1" EXACT [UniProtKB:Q99616] synonym: "Small-inducible cytokine A13" EXACT [UniProtKB:Q99616] xref: EMBL:AAB38703.1 xref: EMBL:AAB67307.1 xref: EMBL:AAD09362.1 xref: EMBL:AAH08621.1 xref: EMBL:AAP36049.1 xref: EMBL:CAA04888.1 xref: EMBL:CAA66950.1 xref: EMBL:CAB01111.1 xref: UniProtKB:O95689 xref: UniProtKB:Q99616 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011281 ! CCL13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020574 ! hnrph3-ccl13 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039348 ! CCL13_HUMAN-acid24 [Term] id: CCO:B0038969 name: CCL11_HUMAN def: "Eotaxin precursor" [UniProtKB:P51671] synonym: "C-C motif chemokine 11" EXACT [UniProtKB:P51671] synonym: "Eosinophil chemotactic protein" EXACT [UniProtKB:P51671] synonym: "Small-inducible cytokine A11" EXACT [UniProtKB:P51671] xref: EMBL:AAA98957.1 xref: EMBL:AAC50369.1 xref: EMBL:AAC51297.1 xref: EMBL:AAH17850.1 xref: EMBL:BAA08370.1 xref: EMBL:CAA93258.1 xref: EMBL:CAA99997.1 xref: EMBL:CAA99998.1 xref: EMBL:CAB07027.1 xref: UniProtKB:P50877 xref: UniProtKB:P51671 xref: UniProtKB:Q92490 xref: UniProtKB:Q92491 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011280 ! CCL11_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0020680 ! tpi1-ccl11 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0038971 name: CCL8_HUMAN def: "C-C motif chemokine 8 precursor" [UniProtKB:P80075] synonym: "HC14" EXACT [UniProtKB:P80075] synonym: "MCP-2" EXACT [UniProtKB:P80075] synonym: "Monocyte chemoattractant protein 2" EXACT [UniProtKB:P80075] synonym: "Monocyte chemotactic protein 2" EXACT [UniProtKB:P80075] synonym: "Small-inducible cytokine A8" EXACT [UniProtKB:P80075] xref: EMBL:AAI26243.1 xref: EMBL:CAA68168.1 xref: EMBL:CAA71760.1 xref: EMBL:CAA76341.1 xref: UniProtKB:A0AV77 xref: UniProtKB:P78388 xref: UniProtKB:P80075 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011285 ! CCL8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039351 ! CCL8_HUMAN-Pyrrolidone carboxylic acid24 [Term] id: CCO:B0038991 name: CSTN1_HUMAN def: "Calsyntenin-1 precursor" [UniProtKB:O94985] synonym: "Alc-alpha" EXACT [UniProtKB:O94985] synonym: "Alcadein-alpha" EXACT [UniProtKB:O94985] synonym: "Alzheimer-related cadherin-like protein" EXACT [UniProtKB:O94985] synonym: "Non-classical cadherin XB31alpha" EXACT [UniProtKB:O94985] xref: EMBL:AAH33902.1 xref: EMBL:AAQ04552.1 xref: EMBL:AAV30551.1 xref: EMBL:BAA74934.2 xref: EMBL:BAF82487.1 xref: EMBL:CAI15699.1 xref: EMBL:CAI15700.1 xref: EMBL:CAI16884.1 xref: EMBL:CAI16885.1 xref: UniProtKB:A8K183 xref: UniProtKB:O94985 xref: UniProtKB:Q5SR52 xref: UniProtKB:Q5UE58 xref: UniProtKB:Q71MN0 xref: UniProtKB:Q8N4K9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011331 ! CLSTN1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0017288 ! kiaa0911-setdb1 physical interaction relationship: participates_in CCO:I0017289 ! kiaa0911-mcm3ap physical interaction [Term] id: CCO:B0039070 name: PHF12_HUMAN def: "PHD finger protein 12" [UniProtKB:Q96QT6] synonym: "Pf1" EXACT [UniProtKB:Q96QT6] synonym: "PHD factor 1" EXACT [UniProtKB:Q96QT6] xref: EMBL:AAH01657.1 xref: EMBL:AAK38349.1 xref: EMBL:BAA96047.1 xref: EMBL:BAB14875.1 xref: EMBL:BAD18713.1 xref: UniProtKB:Q6ZML2 xref: UniProtKB:Q96QT6 xref: UniProtKB:Q9BV34 xref: UniProtKB:Q9H7U9 xref: UniProtKB:Q9P205 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011603 ! PHF12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039586 ! PHF12_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0039587 ! PHF12_HUMAN-Phosphothreonine880 relationship: transforms_into CCO:B0069251 ! PHF12_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0069252 ! PHF12_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0069253 ! PHF12_HUMAN-Phosphothreonine671 [Term] id: CCO:B0039075 name: INHBB_HUMAN def: "Inhibin beta B chain precursor" [UniProtKB:P09529] synonym: "Activin beta-B chain" EXACT [UniProtKB:P09529] xref: EMBL:AAA59169.1 xref: EMBL:AAA59170.1 xref: EMBL:AAA59451.1 xref: EMBL:AAH30029.1 xref: UniProtKB:P09529 xref: UniProtKB:Q8N1D3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011490 ! INHBB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006245 ! host cell surface receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0002742 ! positive regulation of follicle-stimulating hormone secretion relationship: participates_in CCO:P0002743 ! negative regulation of follicle-stimulating hormone secretion relationship: participates_in CCO:P0002794 ! negative regulation of hepatocyte growth factor biosynthetic process [Term] id: CCO:B0039094 name: ZN776_HUMAN def: "Zinc finger protein 776" [UniProtKB:Q68DI1] xref: EMBL:BAC04588.1 xref: EMBL:BAC87119.1 xref: EMBL:CAH18239.1 xref: UniProtKB:Q68DI1 xref: UniProtKB:Q6ZS36 xref: UniProtKB:Q8N968 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011766 ! ZNF776_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039095 name: ZN773_HUMAN def: "Zinc finger protein 773" [UniProtKB:Q6PK81] synonym: "Zinc finger protein 419B" EXACT [UniProtKB:Q6PK81] xref: EMBL:AAH05167.1 xref: EMBL:BAB71382.1 xref: UniProtKB:Q6PK81 xref: UniProtKB:Q96DL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011765 ! ZNF773_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039097 name: A6NLI9_HUMAN def: "Putative uncharacterized protein ZIK1" [UniProtKB:A6NLI9] xref: UniProtKB:A6NLI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011746 ! ZIK1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039099 name: A6NJK9_HUMAN def: "Putative uncharacterized protein ZNF772" [UniProtKB:A6NJK9] xref: UniProtKB:A6NJK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011764 ! ZNF772_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039101 name: ZN548_HUMAN def: "Zinc finger protein 548" [UniProtKB:Q8NEK5] xref: EMBL:AAH30788.1 xref: EMBL:BAB71509.1 xref: UniProtKB:Q8NEK5 xref: UniProtKB:Q96M05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011759 ! ZNF548_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039102 name: ZN419_HUMAN def: "Zinc finger protein 419" [UniProtKB:Q96HQ0] xref: EMBL:AAH08297.1 xref: EMBL:AAH24259.1 xref: EMBL:BAB15582.1 xref: UniProtKB:Q96HQ0 xref: UniProtKB:Q9H5P0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011754 ! ZNF419_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039103 name: A6NKR6_HUMAN def: "Putative uncharacterized protein ZNF772" [UniProtKB:A6NKR6] xref: UniProtKB:A6NKR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011764 ! ZNF772_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039104 name: ZN134_HUMAN def: "Zinc finger protein 134" [UniProtKB:P52741] xref: EMBL:AAC24610.1 xref: EMBL:AAC50253.1 xref: EMBL:AAI12295.1 xref: EMBL:AAI13411.1 xref: EMBL:BAF84452.1 xref: EMBL:EAW72518.1 xref: UniProtKB:P52741 xref: UniProtKB:Q9Y4B2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011748 ! ZNF134_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039105 name: ZN772_HUMAN def: "Zinc finger protein 772" [UniProtKB:Q68DY9] xref: EMBL:CAH18081.1 xref: UniProtKB:Q68DY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011764 ! ZNF772_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039107 name: A6NNZ3_HUMAN def: "Putative uncharacterized protein ZNF419" [UniProtKB:A6NNZ3] xref: UniProtKB:A6NNZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011754 ! ZNF419_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039108 name: ZN211_HUMAN def: "Zinc finger protein 211" [UniProtKB:Q13398] synonym: "Zinc finger protein C2H2-25" EXACT [UniProtKB:Q13398] xref: EMBL:AAA93261.1 xref: EMBL:AAH34351.1 xref: EMBL:AAH89440.1 xref: EMBL:AAI10857.1 xref: EMBL:BAD92510.1 xref: EMBL:BAD93084.1 xref: EMBL:BAG57971.1 xref: EMBL:BAG59491.1 xref: EMBL:BAG59573.1 xref: EMBL:BAG65441.1 xref: UniProtKB:B4DH10 xref: UniProtKB:B4DLC9 xref: UniProtKB:B4E3C9 xref: UniProtKB:Q05BQ7 xref: UniProtKB:Q13398 xref: UniProtKB:Q2TAL7 xref: UniProtKB:Q59EG4 xref: UniProtKB:Q59G36 xref: UniProtKB:Q5EBL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011751 ! ZNF211_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017482 ! mitap1-znf211 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039109 name: ZIK1_HUMAN def: "Zinc finger protein interacting with ribonucleoprotein K" [UniProtKB:Q3SY52] synonym: "Zinc finger protein 762" EXACT [UniProtKB:Q3SY52] xref: EMBL:AAC24608.1 xref: EMBL:AAI03958.1 xref: EMBL:AAI03959.1 xref: EMBL:AAI03960.1 xref: UniProtKB:O43339 xref: UniProtKB:Q3SY51 xref: UniProtKB:Q3SY52 xref: UniProtKB:Q3SY53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011746 ! ZIK1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039112 name: A6NL30_HUMAN def: "Putative uncharacterized protein ZNF419" [UniProtKB:A6NL30] xref: UniProtKB:A6NL30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011754 ! ZNF419_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039113 name: Q59EG4_HUMAN xref: UniProtKB:Q59EG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039114 name: ZN154_HUMAN def: "Zinc finger protein 154" [UniProtKB:Q13106] xref: EMBL:AAC50257.1 xref: EMBL:BAC03839.1 xref: EMBL:BAC23100.1 xref: UniProtKB:Q13106 xref: UniProtKB:Q8IVG7 xref: UniProtKB:Q8NAR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011749 ! ZNF154_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039117 name: A6NGN8_HUMAN def: "Putative uncharacterized protein ZNF551" [UniProtKB:A6NGN8] xref: UniProtKB:A6NGN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011801 ! ZNF551_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039118 name: Q2TAL7_HUMAN xref: UniProtKB:Q2TAL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039119 name: Q59FT8_HUMAN def: "Zinc finger protein 419 variant" [UniProtKB:Q59FT8] xref: EMBL:BAD92608.1 xref: UniProtKB:Q59FT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039136 name: TIGD3_HUMAN def: "Tigger transposable element-derived protein 3" [UniProtKB:Q6B0B8] xref: EMBL:AAH74862.1 xref: UniProtKB:Q6B0B8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011711 ! TIGD3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0039140 name: FOXJ2_HUMAN def: "Forkhead box protein J2" [UniProtKB:Q9P0K8] synonym: "Fork head homologous X" EXACT [UniProtKB:Q9P0K8] xref: EMBL:AAF65927.1 xref: EMBL:AAI26397.1 xref: EMBL:AAK49016.1 xref: EMBL:CAB82315.1 xref: UniProtKB:A0AVK4 xref: UniProtKB:Q96PS9 xref: UniProtKB:Q9NSN5 xref: UniProtKB:Q9P0K8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011391 ! FOXJ2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039424 ! FOXJ2_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0066257 ! FOXJ2_HUMAN-Phosphotyrosine259 relationship: transforms_into CCO:B0066258 ! FOXJ2_HUMAN-Phosphoserine261 [Term] id: CCO:B0039141 name: FOXJ3_HUMAN def: "Forkhead box protein J3" [UniProtKB:Q9UPW0] xref: EMBL:AAH14182.1 xref: EMBL:AAI51829.1 xref: EMBL:AAI52442.1 xref: EMBL:BAA82993.2 xref: EMBL:CAB75651.2 xref: UniProtKB:A7MBL7 xref: UniProtKB:A7MD18 xref: UniProtKB:Q9NSS7 xref: UniProtKB:Q9UPW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011392 ! FOXJ3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017299 ! crsp3-kiaa1041 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066259 ! FOXJ3_HUMAN-Phosphoserine223 [Term] id: CCO:B0039142 name: FOXJ1_HUMAN def: "Forkhead box protein J1" [UniProtKB:Q92949] synonym: "Forkhead-related protein FKHL13" EXACT [UniProtKB:Q92949] synonym: "Hepatocyte nuclear factor 3 forkhead homolog 4" EXACT [UniProtKB:Q92949] synonym: "HFH-4" EXACT [UniProtKB:Q92949] xref: EMBL:AAB09039.1 xref: EMBL:AAH46460.1 xref: EMBL:CAA67729.1 xref: EMBL:CAA67730.1 xref: EMBL:CAB76562.1 xref: UniProtKB:O00630 xref: UniProtKB:Q92949 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011390 ! FOXJ1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000981 ! negative regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001541 ! negative regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0001689 ! activation of Rho GTPase activity relationship: participates_in CCO:P0001773 ! negative regulation of T cell differentiation in the thymus relationship: participates_in CCO:P0002350 ! negative regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002987 ! negative regulation of B cell activation [Term] id: CCO:B0039174 name: MTSSL_HUMAN def: "MTSS1-like protein" [UniProtKB:Q765P7] synonym: "ABBA-1" EXACT [UniProtKB:Q765P7] synonym: "Actin-bundling with BAIAP2 homology protein 1" EXACT [UniProtKB:Q765P7] xref: EMBL:AAH02770.1 xref: EMBL:BAC98378.1 xref: UniProtKB:A6NJI7 xref: UniProtKB:Q765P7 xref: UniProtKB:Q9BUA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011547 ! MTSS1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039535 ! MTSSL_HUMAN-Phosphothreonine260 relationship: transforms_into CCO:B0039536 ! MTSSL_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0039537 ! MTSSL_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0052598 ! MTSSL_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0052599 ! MTSSL_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0052600 ! MTSSL_HUMAN-Phosphoserine601 relationship: transforms_into CCO:B0052601 ! MTSSL_HUMAN-Phosphoserine639 relationship: transforms_into CCO:B0052602 ! MTSSL_HUMAN-Phosphothreonine643 relationship: transforms_into CCO:B0052603 ! MTSSL_HUMAN-Phosphoserine647 relationship: transforms_into CCO:B0068322 ! MTSSL_HUMAN-Phosphoserine441 relationship: transforms_into CCO:B0068323 ! MTSSL_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0068324 ! MTSSL_HUMAN-Phosphoserine579 relationship: transforms_into CCO:B0068325 ! MTSSL_HUMAN-Phosphoserine624 relationship: transforms_into CCO:B0068326 ! MTSSL_HUMAN-Phosphoserine634 [Term] id: CCO:B0039233 name: GBRB2_HUMAN def: "Gamma-aminobutyric acid receptor subunit beta-2 precursor" [UniProtKB:P47870] synonym: "GABA(A) receptor subunit beta-2" EXACT [UniProtKB:P47870] xref: EMBL:AAB29370.1 xref: EMBL:AAB33982.1 xref: EMBL:AAB33983.1 xref: EMBL:AAH99705.1 xref: EMBL:AAH99719.1 xref: EMBL:AAI05640.1 xref: UniProtKB:P47870 xref: UniProtKB:Q16323 xref: UniProtKB:Q4FZB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011423 ! GABRB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway relationship: transforms_into CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: transforms_into CCO:B0039445 ! GBRB2_HUMAN-Phosphotyrosine403 [Term] id: CCO:B0039239 name: GBRB1_HUMAN def: "Gamma-aminobutyric acid receptor subunit beta-1 precursor" [UniProtKB:P18505] synonym: "GABA(A) receptor subunit beta-1" EXACT [UniProtKB:P18505] xref: EMBL:AAA35862.1 xref: EMBL:AAB30712.1 xref: EMBL:AAH22449.1 xref: EMBL:CAA32875.1 xref: UniProtKB:P18505 xref: UniProtKB:Q16166 xref: UniProtKB:Q8TBK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011422 ! GABRB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 [Term] id: CCO:B0039240 name: GBRB3_HUMAN def: "Gamma-aminobutyric acid receptor subunit beta-3 precursor" [UniProtKB:P28472] synonym: "GABA(A) receptor subunit beta-3" EXACT [UniProtKB:P28472] xref: EMBL:AAA52507.1 xref: EMBL:AAA52508.1 xref: EMBL:AAA52511.1 xref: EMBL:AAH10641.1 xref: UniProtKB:P28472 xref: UniProtKB:Q14352 xref: UniProtKB:Q96FM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011424 ! GABRB3_human relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001727 ! terminal button relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0039294 name: 7B2_HUMAN-Phosphoserine205 def: "Protein 7B2_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:P05408] comment: By similarity xref: UniProtKB:P05408 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037954 ! 7B2_HUMAN [Term] id: CCO:B0039295 name: ABI2_HUMAN-Phosphotyrosine462 def: "Protein ABI2_HUMAN with the residue 462 substituted with Phosphotyrosine" [UniProtKB:Q9NYB9] comment: By similarity xref: UniProtKB:Q9NYB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038095 ! ABI2_HUMAN [Term] id: CCO:B0039298 name: ADA1A_HUMAN-Phosphoserine215 def: "Protein ADA1A_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:P35348] comment: by PKA; Potential xref: UniProtKB:P35348 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001279 ! alpha1-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0038258 ! ADA1A_HUMAN [Term] id: CCO:B0039299 name: ADA1B_HUMAN-Phosphothreonine264 def: "Protein ADA1B_HUMAN with the residue 264 substituted with Phosphothreonine" [UniProtKB:P35368] comment: By similarity xref: UniProtKB:P35368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038263 ! ADA1B_HUMAN [Term] id: CCO:B0039300 name: ADA1B_HUMAN-Phosphoserine267 def: "Protein ADA1B_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:P35368] comment: By similarity xref: UniProtKB:P35368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038263 ! ADA1B_HUMAN [Term] id: CCO:B0039301 name: ADA22_HUMAN-Phosphoserine834 def: "Protein ADA22_HUMAN with the residue 834 substituted with Phosphoserine" [UniProtKB:Q9P0K1] comment: By similarity xref: UniProtKB:Q9P0K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0038558 ! ADA22_HUMAN [Term] id: CCO:B0039302 name: ADA22_HUMAN-Phosphoserine866 def: "Protein ADA22_HUMAN with the residue 866 substituted with Phosphoserine" [UniProtKB:Q9P0K1] comment: By similarity xref: UniProtKB:Q9P0K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038558 ! ADA22_HUMAN [Term] id: CCO:B0039303 name: ADA22_HUMAN-Phosphoserine868 def: "Protein ADA22_HUMAN with the residue 868 substituted with Phosphoserine" [UniProtKB:Q9P0K1] comment: By similarity xref: UniProtKB:Q9P0K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038558 ! ADA22_HUMAN [Term] id: CCO:B0039305 name: ADCK1_HUMAN-Phosphothreonine441 def: "Protein ADCK1_HUMAN with the residue 441 substituted with Phosphothreonine" [UniProtKB:Q86TW2] xref: UniProtKB:Q86TW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0038785 ! ADCK1_HUMAN [Term] id: CCO:B0039306 name: ADHX_HUMAN-N-acetylalanine2 def: "Protein ADHX_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P11766] xref: UniProtKB:P11766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000500 ! alcohol dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008204 ! S-(hydroxymethyl)glutathione dehydrogenase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0038020 ! ADHX_HUMAN [Term] id: CCO:B0039318 name: AP2D_HUMAN-Phosphoserine239 def: "Protein AP2D_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q7Z6R9] comment: by PKA; By similarity xref: UniProtKB:Q7Z6R9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0038044 ! AP2D_HUMAN [Term] id: CCO:B0039319 name: AP2E_HUMAN-Phosphoserine246 def: "Protein AP2E_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q6VUC0] comment: by PKA; By similarity xref: UniProtKB:Q6VUC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038043 ! AP2E_HUMAN [Term] id: CCO:B0039321 name: ARC1B_HUMAN-Phosphoserine310 def: "Protein ARC1B_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:O15143] xref: UniProtKB:O15143 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000443 ! Arp2/3 protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0031593 ! ARC1B_HUMAN [Term] id: CCO:B0039329 name: BRPF1_HUMAN-Phosphoserine238 def: "Protein BRPF1_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:P55201] xref: UniProtKB:P55201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038294 ! BRPF1_HUMAN [Term] id: CCO:B0039330 name: BRPF1_HUMAN-Phosphoserine460 def: "Protein BRPF1_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:P55201] xref: UniProtKB:P55201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038294 ! BRPF1_HUMAN [Term] id: CCO:B0039331 name: BRPF1_HUMAN-Phosphoserine462 def: "Protein BRPF1_HUMAN with the residue 462 substituted with Phosphoserine" [UniProtKB:P55201] xref: UniProtKB:P55201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038294 ! BRPF1_HUMAN [Term] id: CCO:B0039332 name: BRPF1_HUMAN-Phosphoserine922 def: "Protein BRPF1_HUMAN with the residue 922 substituted with Phosphoserine" [UniProtKB:P55201] xref: UniProtKB:P55201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0038294 ! BRPF1_HUMAN [Term] id: CCO:B0039334 name: CAP1_HUMAN-N-acetylalanine2 def: "Protein CAP1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0039335 name: CAP1_HUMAN-Phosphotyrosine164 def: "Protein CAP1_HUMAN with the residue 164 substituted with Phosphotyrosine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0039336 name: CAP1_HUMAN-Phosphothreonine307 def: "Protein CAP1_HUMAN with the residue 307 substituted with Phosphothreonine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0039337 name: CAP1_HUMAN-Phosphoserine310 def: "Protein CAP1_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0039338 name: CAP2_HUMAN-Phosphoserine261 def: "Protein CAP2_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:P40123] comment: By similarity xref: UniProtKB:P40123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023918 ! CAP2_HUMAN [Term] id: CCO:B0039339 name: CAP2_HUMAN-Phosphoserine301 def: "Protein CAP2_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:P40123] xref: UniProtKB:P40123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0023918 ! CAP2_HUMAN [Term] id: CCO:B0039340 name: CAZA1_HUMAN-N-acetylalanine2 def: "Protein CAZA1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P52907] xref: UniProtKB:P52907 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000542 ! F-actin capping protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0037567 ! CAZA1_HUMAN [Term] id: CCO:B0039348 name: CCL13_HUMAN-acid24 def: "Protein CCL13_HUMAN with the residue 24 substituted with acid" [UniProtKB:Q99616] comment: in short chain; xref: UniProtKB:Q99616 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0038966 ! CCL13_HUMAN [Term] id: CCO:B0039349 name: CCL2_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein CCL2_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P13500] xref: UniProtKB:P13500 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0038965 ! CCL2_HUMAN [Term] id: CCO:B0039350 name: CCL7_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein CCL7_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P80098] xref: UniProtKB:P80098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038963 ! CCL7_HUMAN [Term] id: CCO:B0039351 name: CCL8_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein CCL8_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P80075] xref: UniProtKB:P80075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0038971 ! CCL8_HUMAN [Term] id: CCO:B0039354 name: CDX2_HUMAN-Phosphoserine60 def: "Protein CDX2_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q99626] comment: By similarity xref: UniProtKB:Q99626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000121 ! condensed nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0036829 ! CDX2_HUMAN [Term] id: CCO:B0039355 name: CHSP1_HUMAN-Phosphoserine30 def: "Protein CHSP1_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q9Y2V2] xref: UniProtKB:Q9Y2V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021340 ! CHSP1_HUMAN [Term] id: CCO:B0039356 name: CHSP1_HUMAN-Phosphoserine32 def: "Protein CHSP1_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q9Y2V2] xref: UniProtKB:Q9Y2V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021340 ! CHSP1_HUMAN [Term] id: CCO:B0039357 name: CHSP1_HUMAN-Phosphoserine41 def: "Protein CHSP1_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q9Y2V2] xref: UniProtKB:Q9Y2V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021340 ! CHSP1_HUMAN [Term] id: CCO:B0039358 name: CHSP1_HUMAN-Phosphoserine52 def: "Protein CHSP1_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q9Y2V2] xref: UniProtKB:Q9Y2V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021340 ! CHSP1_HUMAN [Term] id: CCO:B0039359 name: CO3_HUMAN-Phosphotyrosine489 def: "Protein CO3_HUMAN with the residue 489 substituted with Phosphotyrosine" [UniProtKB:P01024] comment: By similarity xref: UniProtKB:P01024 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036109 ! CO3_HUMAN [Term] id: CCO:B0039366 name: COPA_HUMAN-Phosphoserine173 def: "Protein COPA_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:P53621] xref: UniProtKB:P53621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038202 ! COPA_HUMAN [Term] id: CCO:B0039367 name: COPA_HUMAN-Phosphotyrosine249 def: "Protein COPA_HUMAN with the residue 249 substituted with Phosphotyrosine" [UniProtKB:P53621] xref: UniProtKB:P53621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000971 ! COPI vesicle coat relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0038202 ! COPA_HUMAN [Term] id: CCO:B0039368 name: COPA_HUMAN-Phosphoserine402 def: "Protein COPA_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:P53621] xref: UniProtKB:P53621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038202 ! COPA_HUMAN [Term] id: CCO:B0039370 name: CPIN1_HUMAN-Phosphoserine182 def: "Protein CPIN1_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q6FI81] xref: UniProtKB:Q6FI81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019428 ! CPIN1_HUMAN [Term] id: CCO:B0039371 name: CPIN1_HUMAN-Phosphoserine183 def: "Protein CPIN1_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q6FI81] xref: UniProtKB:Q6FI81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019428 ! CPIN1_HUMAN [Term] id: CCO:B0039372 name: CPIN1_HUMAN-Phosphoserine185 def: "Protein CPIN1_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:Q6FI81] xref: UniProtKB:Q6FI81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0019428 ! CPIN1_HUMAN [Term] id: CCO:B0039373 name: CPIN1_HUMAN-Phosphoserine307 def: "Protein CPIN1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q6FI81] xref: UniProtKB:Q6FI81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019428 ! CPIN1_HUMAN [Term] id: CCO:B0039378 name: DAPK2_HUMAN-Phosphoserine318 def: "Protein DAPK2_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q9UIK4] comment: by autocatalysis; xref: UniProtKB:Q9UIK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0036525 ! DAPK2_HUMAN [Term] id: CCO:B0039379 name: DAPK2_HUMAN-Phosphoserine349 def: "Protein DAPK2_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q9UIK4] xref: UniProtKB:Q9UIK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036525 ! DAPK2_HUMAN [Term] id: CCO:B0039380 name: DEPD6_HUMAN-Phosphoserine235 def: "Protein DEPD6_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q8TB45] comment: By similarity xref: UniProtKB:Q8TB45 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037020 ! DEPD6_HUMAN [Term] id: CCO:B0039381 name: DEPD6_HUMAN-Phosphoserine238 def: "Protein DEPD6_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q8TB45] comment: By similarity xref: UniProtKB:Q8TB45 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037020 ! DEPD6_HUMAN [Term] id: CCO:B0039382 name: DEPD6_HUMAN-Phosphoserine287 def: "Protein DEPD6_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q8TB45] comment: By similarity xref: UniProtKB:Q8TB45 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037020 ! DEPD6_HUMAN [Term] id: CCO:B0039391 name: DLG2_HUMAN-Phosphoserine28 def: "Protein DLG2_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039392 name: DLG2_HUMAN-Phosphotyrosine58 def: "Protein DLG2_HUMAN with the residue 58 substituted with Phosphotyrosine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039393 name: DLG2_HUMAN-Phosphoserine62 def: "Protein DLG2_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039394 name: DLG2_HUMAN-Phosphoserine175 def: "Protein DLG2_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039395 name: DLG2_HUMAN-Phosphotyrosine340 def: "Protein DLG2_HUMAN with the residue 340 substituted with Phosphotyrosine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039396 name: DLG2_HUMAN-Phosphotyrosine348 def: "Protein DLG2_HUMAN with the residue 348 substituted with Phosphotyrosine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039397 name: DLG2_HUMAN-Phosphoserine365 def: "Protein DLG2_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q15700] xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039398 name: DLG2_HUMAN-Phosphoserine406 def: "Protein DLG2_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039399 name: DLG2_HUMAN-Phosphoserine414 def: "Protein DLG2_HUMAN with the residue 414 substituted with Phosphoserine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039400 name: DLG2_HUMAN-Phosphotyrosine500 def: "Protein DLG2_HUMAN with the residue 500 substituted with Phosphotyrosine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039401 name: DLG2_HUMAN-Phosphotyrosine505 def: "Protein DLG2_HUMAN with the residue 505 substituted with Phosphotyrosine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039402 name: DLG2_HUMAN-Phosphotyrosine750 def: "Protein DLG2_HUMAN with the residue 750 substituted with Phosphotyrosine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039403 name: DLG2_HUMAN-Phosphotyrosine755 def: "Protein DLG2_HUMAN with the residue 755 substituted with Phosphotyrosine" [UniProtKB:Q15700] comment: By similarity xref: UniProtKB:Q15700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:B0039404 name: DNM3A_HUMAN-Phosphoserine105 def: "Protein DNM3A_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q9Y6K1] xref: UniProtKB:Q9Y6K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000405 ! DNA (cytosine-5-)-methyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000118 ! euchromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:B0039414 name: EPHB1_HUMAN-Phosphoserine968 def: "Protein EPHB1_HUMAN with the residue 968 substituted with Phosphoserine" [UniProtKB:P54762] xref: UniProtKB:P54762 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014969 ! EPHB1_HUMAN [Term] id: CCO:B0039424 name: FOXJ2_HUMAN-Phosphoserine161 def: "Protein FOXJ2_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q9P0K8] xref: UniProtKB:Q9P0K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0039140 ! FOXJ2_HUMAN [Term] id: CCO:B0039425 name: FOXK1_HUMAN-Phosphoserine213 def: "Protein FOXK1_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039426 name: FOXK1_HUMAN-Phosphoserine223 def: "Protein FOXK1_HUMAN with the residue 223 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039427 name: FOXK1_HUMAN-Phosphoserine416 def: "Protein FOXK1_HUMAN with the residue 416 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039428 name: FOXK1_HUMAN-Phosphoserine420 def: "Protein FOXK1_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039429 name: FOXK1_HUMAN-Phosphothreonine422 def: "Protein FOXK1_HUMAN with the residue 422 substituted with Phosphothreonine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039430 name: FOXK1_HUMAN-Phosphoserine428 def: "Protein FOXK1_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039431 name: FOXK1_HUMAN-Phosphothreonine436 def: "Protein FOXK1_HUMAN with the residue 436 substituted with Phosphothreonine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039432 name: FOXK1_HUMAN-Phosphoserine441 def: "Protein FOXK1_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039433 name: FOXK1_HUMAN-Phosphoserine445 def: "Protein FOXK1_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0039434 name: FOXK2_HUMAN-Phosphoserine61 def: "Protein FOXK2_HUMAN with the residue 61 substituted with Phosphoserine" [UniProtKB:Q01167] xref: UniProtKB:Q01167 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015238 ! FOXK2_HUMAN [Term] id: CCO:B0039435 name: FOXK2_HUMAN-Phosphoserine239 def: "Protein FOXK2_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q01167] xref: UniProtKB:Q01167 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015238 ! FOXK2_HUMAN [Term] id: CCO:B0039436 name: FOXK2_HUMAN-Phosphoserine398 def: "Protein FOXK2_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:Q01167] xref: UniProtKB:Q01167 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015238 ! FOXK2_HUMAN [Term] id: CCO:B0039437 name: FOXP4_HUMAN-Phosphoserine360 def: "Protein FOXP4_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q8IVH2] xref: UniProtKB:Q8IVH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0015713 ! FOXP4_HUMAN [Term] id: CCO:B0039438 name: FRAP_HUMAN-Phosphothreonine1162 def: "Protein FRAP_HUMAN with the residue 1162 substituted with Phosphothreonine" [UniProtKB:P42345] xref: UniProtKB:P42345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001611 ! FRAP_HUMAN [Term] id: CCO:B0039440 name: GBRA1_HUMAN-Phosphotyrosine368 def: "Protein GBRA1_HUMAN with the residue 368 substituted with Phosphotyrosine" [UniProtKB:P14867] comment: By similarity xref: UniProtKB:P14867 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022914 ! GBRA1_HUMAN [Term] id: CCO:B0039441 name: GBRA1_HUMAN-Phosphotyrosine375 def: "Protein GBRA1_HUMAN with the residue 375 substituted with Phosphotyrosine" [UniProtKB:P14867] comment: By similarity xref: UniProtKB:P14867 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022914 ! GBRA1_HUMAN [Term] id: CCO:B0039442 name: GBRA3_HUMAN-Phosphoserine433 def: "Protein GBRA3_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:P34903] comment: By similarity xref: UniProtKB:P34903 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022933 ! GBRA3_HUMAN [Term] id: CCO:B0039443 name: GBRB1_HUMAN-Phosphoserine448 def: "Protein GBRB1_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:P18505] xref: UniProtKB:P18505 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0039239 ! GBRB1_HUMAN [Term] id: CCO:B0039444 name: GBRB2_HUMAN-Phosphotyrosine396 def: "Protein GBRB2_HUMAN with the residue 396 substituted with Phosphotyrosine" [UniProtKB:P47870] comment: By similarity xref: UniProtKB:P47870 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0039233 ! GBRB2_HUMAN [Term] id: CCO:B0039445 name: GBRB2_HUMAN-Phosphotyrosine403 def: "Protein GBRB2_HUMAN with the residue 403 substituted with Phosphotyrosine" [UniProtKB:P47870] comment: By similarity xref: UniProtKB:P47870 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039233 ! GBRB2_HUMAN [Term] id: CCO:B0039447 name: GSTM1_HUMAN-Phosphotyrosine23 def: "Protein GSTM1_HUMAN with the residue 23 substituted with Phosphotyrosine" [UniProtKB:P09488] comment: By similarity xref: UniProtKB:P09488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000783 ! glutathione transferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0038241 ! GSTM1_HUMAN [Term] id: CCO:B0039448 name: GSTM1_HUMAN-Phosphotyrosine33 def: "Protein GSTM1_HUMAN with the residue 33 substituted with Phosphotyrosine" [UniProtKB:P09488] comment: By similarity xref: UniProtKB:P09488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038241 ! GSTM1_HUMAN [Term] id: CCO:B0039449 name: GSTM1_HUMAN-Phosphothreonine34 def: "Protein GSTM1_HUMAN with the residue 34 substituted with Phosphothreonine" [UniProtKB:P09488] comment: By similarity xref: UniProtKB:P09488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038241 ! GSTM1_HUMAN [Term] id: CCO:B0039450 name: GSTP1_HUMAN-Phosphotyrosine109 def: "Protein GSTP1_HUMAN with the residue 109 substituted with Phosphotyrosine" [UniProtKB:P09211] comment: By similarity xref: UniProtKB:P09211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006145 ! GSTP1_HUMAN [Term] id: CCO:B0039451 name: HABP4_HUMAN-Phosphothreonine354 def: "Protein HABP4_HUMAN with the residue 354 substituted with Phosphothreonine" [UniProtKB:Q5JVS0] comment: by PKC; Probable xref: UniProtKB:Q5JVS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037756 ! HABP4_HUMAN [Term] id: CCO:B0039452 name: HABP4_HUMAN-Phosphothreonine375 def: "Protein HABP4_HUMAN with the residue 375 substituted with Phosphothreonine" [UniProtKB:Q5JVS0] comment: by PKC; Probable xref: UniProtKB:Q5JVS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037756 ! HABP4_HUMAN [Term] id: CCO:B0039454 name: HILS1_HUMAN-Phosphothreonine130 def: "Protein HILS1_HUMAN with the residue 130 substituted with Phosphothreonine" [UniProtKB:P60008] comment: Potential xref: UniProtKB:P60008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000178 ! male germ cell nucleus relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0036287 ! HILS1_HUMAN [Term] id: CCO:B0039457 name: HNF4A_HUMAN-Phosphothreonine429 def: "Protein HNF4A_HUMAN with the residue 429 substituted with Phosphothreonine" [UniProtKB:P41235] comment: By similarity xref: UniProtKB:P41235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0036934 ! HNF4A_HUMAN [Term] id: CCO:B0039458 name: HNF4A_HUMAN-Phosphothreonine432 def: "Protein HNF4A_HUMAN with the residue 432 substituted with Phosphothreonine" [UniProtKB:P41235] comment: By similarity xref: UniProtKB:P41235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036934 ! HNF4A_HUMAN [Term] id: CCO:B0039459 name: HPRT_HUMAN-N-acetylalanine2 def: "Protein HPRT_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P00492] xref: UniProtKB:P00492 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036957 ! HPRT_HUMAN [Term] id: CCO:B0039460 name: HXB6_HUMAN-Phosphoserine211 def: "Protein HXB6_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:P17509] xref: UniProtKB:P17509 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036826 ! HXB6_HUMAN [Term] id: CCO:B0039461 name: HXB6_HUMAN-Phosphoserine214 def: "Protein HXB6_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:P17509] xref: UniProtKB:P17509 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0036826 ! HXB6_HUMAN [Term] id: CCO:B0039462 name: IF4E_HUMAN-Phosphoserine209 def: "Protein IF4E_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:P06730] comment: by PKC; xref: UniProtKB:P06730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016186 ! IF4E_HUMAN [Term] id: CCO:B0039463 name: IF5A1_HUMAN-Blocked amino end (Ala)2 def: "Protein IF5A1_HUMAN with the residue 2 substituted with Blocked amino end (Ala)" [UniProtKB:P63241] comment: Probable xref: UniProtKB:P63241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003545 ! U6 snRNA binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000259 ! annulate lamellae relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0036567 ! IF5A1_HUMAN [Term] id: CCO:B0039464 name: IF5A1_HUMAN-Hypusine50 def: "Protein IF5A1_HUMAN with the residue 50 substituted with Hypusine" [UniProtKB:P63241] xref: UniProtKB:P63241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036567 ! IF5A1_HUMAN [Term] id: CCO:B0039465 name: IF5A1_HUMAN-N6-acetyllysine68 def: "Protein IF5A1_HUMAN with the residue 68 substituted with N6-acetyllysine" [UniProtKB:P63241] xref: UniProtKB:P63241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036567 ! IF5A1_HUMAN [Term] id: CCO:B0039466 name: IF5A2_HUMAN-Blocked amino end (Ala)2 def: "Protein IF5A2_HUMAN with the residue 2 substituted with Blocked amino end (Ala)" [UniProtKB:Q9GZV4] comment: By similarity xref: UniProtKB:Q9GZV4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036577 ! IF5A2_HUMAN [Term] id: CCO:B0039467 name: IF5A2_HUMAN-Hypusine50 def: "Protein IF5A2_HUMAN with the residue 50 substituted with Hypusine" [UniProtKB:Q9GZV4] xref: UniProtKB:Q9GZV4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0036577 ! IF5A2_HUMAN [Term] id: CCO:B0039468 name: IF5A2_HUMAN-N6-acetyllysine68 def: "Protein IF5A2_HUMAN with the residue 68 substituted with N6-acetyllysine" [UniProtKB:Q9GZV4] xref: UniProtKB:Q9GZV4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036577 ! IF5A2_HUMAN [Term] id: CCO:B0039469 name: IFNB_HUMAN-Phosphoserine140 def: "Protein IFNB_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P01574] xref: UniProtKB:P01574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015966 ! IFNB_HUMAN [Term] id: CCO:B0039470 name: IKZF2_HUMAN-Phosphoserine174 def: "Protein IKZF2_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:Q9UKS7] xref: UniProtKB:Q9UKS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0021859 ! IKZF2_HUMAN [Term] id: CCO:B0039471 name: IKZF2_HUMAN-Phosphotyrosine175 def: "Protein IKZF2_HUMAN with the residue 175 substituted with Phosphotyrosine" [UniProtKB:Q9UKS7] xref: UniProtKB:Q9UKS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021859 ! IKZF2_HUMAN [Term] id: CCO:B0039472 name: IMA1_HUMAN-Phosphothreonine3 def: "Protein IMA1_HUMAN with the residue 3 substituted with Phosphothreonine" [UniProtKB:P52294] comment: By similarity xref: UniProtKB:P52294 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001742 ! nuclear localization sequence binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0020532 ! IMA1_HUMAN [Term] id: CCO:B0039473 name: IMA7_HUMAN-Phosphoserine6 def: "Protein IMA7_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:O60684] comment: By similarity xref: UniProtKB:O60684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020529 ! IMA7_HUMAN [Term] id: CCO:B0039474 name: IRF7_HUMAN-Phosphoserine471 def: "Protein IRF7_HUMAN with the residue 471 substituted with Phosphoserine" [UniProtKB:Q92985] comment: By similarity xref: UniProtKB:Q92985 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037928 ! IRF7_HUMAN [Term] id: CCO:B0039475 name: IRF7_HUMAN-Phosphoserine472 def: "Protein IRF7_HUMAN with the residue 472 substituted with Phosphoserine" [UniProtKB:Q92985] comment: By similarity xref: UniProtKB:Q92985 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037928 ! IRF7_HUMAN [Term] id: CCO:B0039476 name: IRF7_HUMAN-Phosphoserine483 def: "Protein IRF7_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:Q92985] comment: By similarity xref: UniProtKB:Q92985 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037928 ! IRF7_HUMAN [Term] id: CCO:B0039477 name: IRF7_HUMAN-Phosphoserine484 def: "Protein IRF7_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:Q92985] comment: By similarity xref: UniProtKB:Q92985 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0037928 ! IRF7_HUMAN [Term] id: CCO:B0039478 name: K1967_HUMAN-Phosphoserine124 def: "Protein K1967_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q8N163] xref: UniProtKB:Q8N163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:B0039479 name: K1967_HUMAN-Phosphothreonine454 def: "Protein K1967_HUMAN with the residue 454 substituted with Phosphothreonine" [UniProtKB:Q8N163] xref: UniProtKB:Q8N163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:B0039480 name: K1967_HUMAN-Phosphoserine675 def: "Protein K1967_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:Q8N163] xref: UniProtKB:Q8N163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:B0039481 name: K1967_HUMAN-Phosphoserine678 def: "Protein K1967_HUMAN with the residue 678 substituted with Phosphoserine" [UniProtKB:Q8N163] xref: UniProtKB:Q8N163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:B0039482 name: K1967_HUMAN-Phosphoserine681 def: "Protein K1967_HUMAN with the residue 681 substituted with Phosphoserine" [UniProtKB:Q8N163] xref: UniProtKB:Q8N163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:B0039483 name: KI18A_HUMAN-Phosphoserine357 def: "Protein KI18A_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q8NI77] xref: UniProtKB:Q8NI77 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0026171 ! KI18A_HUMAN [Term] id: CCO:B0039484 name: LIPB2_HUMAN-Phosphoserine385 def: "Protein LIPB2_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:Q8ND30] comment: By similarity xref: UniProtKB:Q8ND30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0037978 ! LIPB2_HUMAN [Term] id: CCO:B0039485 name: LIPB2_HUMAN-Phosphoserine512 def: "Protein LIPB2_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q8ND30] comment: By similarity xref: UniProtKB:Q8ND30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037978 ! LIPB2_HUMAN [Term] id: CCO:B0039489 name: M3K7_HUMAN-Phosphothreonine184 def: "Protein M3K7_HUMAN with the residue 184 substituted with Phosphothreonine" [UniProtKB:O43318] comment: by autocatalysis; Probable xref: UniProtKB:O43318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:B0039490 name: M3K7_HUMAN-Phosphothreonine187 def: "Protein M3K7_HUMAN with the residue 187 substituted with Phosphothreonine" [UniProtKB:O43318] comment: by autocatalysis; Probable xref: UniProtKB:O43318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:B0039491 name: M3K7_HUMAN-Phosphoserine192 def: "Protein M3K7_HUMAN with the residue 192 substituted with Phosphoserine" [UniProtKB:O43318] comment: by autocatalysis; Probable xref: UniProtKB:O43318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:B0039492 name: M3K7_HUMAN-Phosphoserine439 def: "Protein M3K7_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:O43318] xref: UniProtKB:O43318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:B0039493 name: M3K9_HUMAN-Phosphothreonine304 def: "Protein M3K9_HUMAN with the residue 304 substituted with Phosphothreonine" [UniProtKB:P80192] comment: by autocatalysis; xref: UniProtKB:P80192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038544 ! M3K9_HUMAN [Term] id: CCO:B0039494 name: M3K9_HUMAN-Phosphoserine308 def: "Protein M3K9_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:P80192] comment: by autocatalysis; xref: UniProtKB:P80192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038544 ! M3K9_HUMAN [Term] id: CCO:B0039495 name: M3K9_HUMAN-Phosphothreonine312 def: "Protein M3K9_HUMAN with the residue 312 substituted with Phosphothreonine" [UniProtKB:P80192] comment: by autocatalysis; xref: UniProtKB:P80192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038544 ! M3K9_HUMAN [Term] id: CCO:B0039496 name: M3K9_HUMAN-Phosphoserine552 def: "Protein M3K9_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:P80192] comment: By similarity xref: UniProtKB:P80192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038544 ! M3K9_HUMAN [Term] id: CCO:B0039497 name: M3K9_HUMAN-Phosphoserine931 def: "Protein M3K9_HUMAN with the residue 931 substituted with Phosphoserine" [UniProtKB:P80192] comment: By similarity xref: UniProtKB:P80192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038544 ! M3K9_HUMAN [Term] id: CCO:B0039498 name: M3K9_HUMAN-Phosphoserine934 def: "Protein M3K9_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:P80192] comment: By similarity xref: UniProtKB:P80192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001072 ! JUN kinase kinase kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0038544 ! M3K9_HUMAN [Term] id: CCO:B0039499 name: M3K9_HUMAN-Phosphoserine998 def: "Protein M3K9_HUMAN with the residue 998 substituted with Phosphoserine" [UniProtKB:P80192] comment: By similarity xref: UniProtKB:P80192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038544 ! M3K9_HUMAN [Term] id: CCO:B0039500 name: MARK1_HUMAN-Phosphothreonine215 def: "Protein MARK1_HUMAN with the residue 215 substituted with Phosphothreonine" [UniProtKB:Q9P0L2] xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0039501 name: MARK1_HUMAN-Phosphoserine219 def: "Protein MARK1_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q9P0L2] comment: By similarity xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0039502 name: MARK1_HUMAN-Phosphoserine394 def: "Protein MARK1_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q9P0L2] comment: By similarity xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0039503 name: MARK1_HUMAN-Phosphoserine403 def: "Protein MARK1_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:Q9P0L2] comment: By similarity xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0039504 name: MARK1_HUMAN-Phosphoserine649 def: "Protein MARK1_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:Q9P0L2] xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0039505 name: MARK1_HUMAN-Phosphoserine666 def: "Protein MARK1_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:Q9P0L2] comment: By similarity xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0039506 name: MARK2_HUMAN-Phosphoserine40 def: "Protein MARK2_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039507 name: MARK2_HUMAN-Phosphothreonine208 def: "Protein MARK2_HUMAN with the residue 208 substituted with Phosphothreonine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039508 name: MARK2_HUMAN-Phosphoserine212 def: "Protein MARK2_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q7KZI7] comment: By similarity xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039509 name: MARK2_HUMAN-Phosphoserine456 def: "Protein MARK2_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039510 name: MARK2_HUMAN-Phosphothreonine469 def: "Protein MARK2_HUMAN with the residue 469 substituted with Phosphothreonine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039511 name: MARK2_HUMAN-Phosphoserine479 def: "Protein MARK2_HUMAN with the residue 479 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039512 name: MARK2_HUMAN-Phosphoserine486 def: "Protein MARK2_HUMAN with the residue 486 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039513 name: MARK2_HUMAN-Phosphoserine569 def: "Protein MARK2_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039514 name: MARK2_HUMAN-Phosphoserine571 def: "Protein MARK2_HUMAN with the residue 571 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039515 name: MARK2_HUMAN-Phosphothreonine596 def: "Protein MARK2_HUMAN with the residue 596 substituted with Phosphothreonine" [UniProtKB:Q7KZI7] comment: by PKC/PRKCZ; xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039516 name: MARK2_HUMAN-Phosphoserine619 def: "Protein MARK2_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039517 name: MARK2_HUMAN-Phosphoserine631 def: "Protein MARK2_HUMAN with the residue 631 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0039518 name: MAST1_HUMAN-Phosphoserine161 def: "Protein MAST1_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q9Y2H9] xref: UniProtKB:Q9Y2H9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0036609 ! MAST1_HUMAN [Term] id: CCO:B0039519 name: MAST1_HUMAN-Phosphoserine163 def: "Protein MAST1_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:Q9Y2H9] xref: UniProtKB:Q9Y2H9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036609 ! MAST1_HUMAN [Term] id: CCO:B0039525 name: MP2K3_HUMAN-Phosphoserine218 def: "Protein MP2K3_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:P46734] xref: UniProtKB:P46734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020948 ! MP2K3_HUMAN [Term] id: CCO:B0039526 name: MP2K3_HUMAN-Phosphothreonine222 def: "Protein MP2K3_HUMAN with the residue 222 substituted with Phosphothreonine" [UniProtKB:P46734] xref: UniProtKB:P46734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020948 ! MP2K3_HUMAN [Term] id: CCO:B0039535 name: MTSSL_HUMAN-Phosphothreonine260 def: "Protein MTSSL_HUMAN with the residue 260 substituted with Phosphothreonine" [UniProtKB:Q765P7] comment: By similarity xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0039536 name: MTSSL_HUMAN-Phosphoserine264 def: "Protein MTSSL_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q765P7] comment: By similarity xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0039537 name: MTSSL_HUMAN-Phosphoserine612 def: "Protein MTSSL_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0039538 name: MYLK2_HUMAN-N-acetylalanine2 def: "Protein MYLK2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9H1R3] comment: By similarity xref: UniProtKB:Q9H1R3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036526 ! MYLK2_HUMAN [Term] id: CCO:B0039539 name: MYLK_HUMAN-Phosphoserine343 def: "Protein MYLK_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:Q15746] comment: By similarity xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0039540 name: MYLK_HUMAN-Phosphotyrosine464 def: "Protein MYLK_HUMAN with the residue 464 substituted with Phosphotyrosine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0039541 name: MYLK_HUMAN-Phosphotyrosine471 def: "Protein MYLK_HUMAN with the residue 471 substituted with Phosphotyrosine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0039542 name: MYLK_HUMAN-Phosphoserine814 def: "Protein MYLK_HUMAN with the residue 814 substituted with Phosphoserine" [UniProtKB:Q15746] comment: By similarity xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0039543 name: MYLK_HUMAN-Phosphoserine1759 def: "Protein MYLK_HUMAN with the residue 1759 substituted with Phosphoserine" [UniProtKB:Q15746] comment: By similarity xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0039544 name: MYLK_HUMAN-Phosphoserine1776 def: "Protein MYLK_HUMAN with the residue 1776 substituted with Phosphoserine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0039545 name: MYO9B_HUMAN-Phosphoserine1267 def: "Protein MYO9B_HUMAN with the residue 1267 substituted with Phosphoserine" [UniProtKB:Q13459] xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0039546 name: MYO9B_HUMAN-Phosphothreonine1271 def: "Protein MYO9B_HUMAN with the residue 1271 substituted with Phosphothreonine" [UniProtKB:Q13459] xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0039547 name: MYO9B_HUMAN-Phosphothreonine1348 def: "Protein MYO9B_HUMAN with the residue 1348 substituted with Phosphothreonine" [UniProtKB:Q13459] comment: By similarity xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0039548 name: MYO9B_HUMAN-Phosphoserine1993 def: "Protein MYO9B_HUMAN with the residue 1993 substituted with Phosphoserine" [UniProtKB:Q13459] xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000026 ! microfilament motor activity relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005867 ! ADP binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0001356 ! filamentous actin relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0039573 name: NSF_HUMAN-Phosphotyrosine259 def: "Protein NSF_HUMAN with the residue 259 substituted with Phosphotyrosine" [UniProtKB:P46459] comment: By similarity xref: UniProtKB:P46459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0038850 ! NSF_HUMAN [Term] id: CCO:B0039578 name: PEPD_HUMAN-N-acetylalanine2 def: "Protein PEPD_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P12955] comment: Potential xref: UniProtKB:P12955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000697 ! X-Pro dipeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001785 ! metalloexopeptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001914 ! X-Pro aminopeptidase activity relationship: has_function CCO:F0001933 ! metallocarboxypeptidase D activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003375 ! dipeptidase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036047 ! PEPD_HUMAN [Term] id: CCO:B0039579 name: PEPD_HUMAN-Phosphothreonine188 def: "Protein PEPD_HUMAN with the residue 188 substituted with Phosphothreonine" [UniProtKB:P12955] xref: UniProtKB:P12955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036047 ! PEPD_HUMAN [Term] id: CCO:B0039580 name: PEPD_HUMAN-Phosphothreonine487 def: "Protein PEPD_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:P12955] xref: UniProtKB:P12955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036047 ! PEPD_HUMAN [Term] id: CCO:B0039581 name: PGFRA_HUMAN-Phosphotyrosine720 def: "Protein PGFRA_HUMAN with the residue 720 substituted with Phosphotyrosine" [UniProtKB:P16234] comment: Probable xref: UniProtKB:P16234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001350 ! platelet-derived growth factor alpha-receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007337 ! platelet-derived growth factor binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0020505 ! PGFRA_HUMAN [Term] id: CCO:B0039586 name: PHF12_HUMAN-Phosphoserine131 def: "Protein PHF12_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:Q96QT6] xref: UniProtKB:Q96QT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039070 ! PHF12_HUMAN [Term] id: CCO:B0039587 name: PHF12_HUMAN-Phosphothreonine880 def: "Protein PHF12_HUMAN with the residue 880 substituted with Phosphothreonine" [UniProtKB:Q96QT6] xref: UniProtKB:Q96QT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039070 ! PHF12_HUMAN [Term] id: CCO:B0039588 name: PLS1_HUMAN-Phosphotyrosine69 def: "Protein PLS1_HUMAN with the residue 69 substituted with Phosphotyrosine" [UniProtKB:O15162] comment: by ABL; xref: UniProtKB:O15162 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003585 ! phospholipid scramblase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:B0039589 name: PLS1_HUMAN-Phosphotyrosine74 def: "Protein PLS1_HUMAN with the residue 74 substituted with Phosphotyrosine" [UniProtKB:O15162] comment: by ABL; xref: UniProtKB:O15162 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:B0039590 name: PLS1_HUMAN-Phosphothreonine161 def: "Protein PLS1_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:O15162] comment: by PKC; xref: UniProtKB:O15162 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:B0039592 name: PLST_HUMAN-Phosphoserine474 def: "Protein PLST_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:P13797] xref: UniProtKB:P13797 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0019585 ! PLST_HUMAN [Term] id: CCO:B0039593 name: PLST_HUMAN-Phosphothreonine489 def: "Protein PLST_HUMAN with the residue 489 substituted with Phosphothreonine" [UniProtKB:P13797] xref: UniProtKB:P13797 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019585 ! PLST_HUMAN [Term] id: CCO:B0039594 name: PMS2L_HUMAN-Phosphoserine92 def: "Protein PMS2L_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q68D20] xref: UniProtKB:Q68D20 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025455 ! PMS2L_HUMAN [Term] id: CCO:B0039595 name: POLK_HUMAN-Phosphothreonine372 def: "Protein POLK_HUMAN with the residue 372 substituted with Phosphothreonine" [UniProtKB:Q9UBT6] xref: UniProtKB:Q9UBT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024762 ! POLK_HUMAN [Term] id: CCO:B0039596 name: PREX1_HUMAN-Phosphoserine436 def: "Protein PREX1_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q8TCU6] xref: UniProtKB:Q8TCU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0037021 ! PREX1_HUMAN [Term] id: CCO:B0039597 name: PRS10_HUMAN-N-acetylalanine2 def: "Protein PRS10_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62333] xref: UniProtKB:P62333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: transformation_of CCO:B0030905 ! PRS10_HUMAN [Term] id: CCO:B0039598 name: PSD12_HUMAN-N-acetylalanine2 def: "Protein PSD12_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O00232] xref: UniProtKB:O00232 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002079 ! proteasome regulatory particle relationship: transformation_of CCO:B0038144 ! PSD12_HUMAN [Term] id: CCO:B0039599 name: PTBP1_HUMAN-N-acetylmethionine1 def: "Protein PTBP1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P26599] xref: UniProtKB:P26599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037269 ! PTBP1_HUMAN [Term] id: CCO:B0039600 name: PTBP1_HUMAN-Phosphoserine141 def: "Protein PTBP1_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:P26599] xref: UniProtKB:P26599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001768 ! poly-pyrimidine tract binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0037269 ! PTBP1_HUMAN [Term] id: CCO:B0039601 name: PTBP1_HUMAN-Phosphoserine433 def: "Protein PTBP1_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:P26599] xref: UniProtKB:P26599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037269 ! PTBP1_HUMAN [Term] id: CCO:B0039610 name: RAGP1_HUMAN-Phosphoserine428 def: "Protein RAGP1_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:P46060] xref: UniProtKB:P46060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001403 ! Ran GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0037521 ! RAGP1_HUMAN [Term] id: CCO:B0039611 name: RAGP1_HUMAN-Phosphoserine442 def: "Protein RAGP1_HUMAN with the residue 442 substituted with Phosphoserine" [UniProtKB:P46060] xref: UniProtKB:P46060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037521 ! RAGP1_HUMAN [Term] id: CCO:B0039612 name: RB11A_HUMAN-N-acetylglycine2 def: "Protein RB11A_HUMAN with the residue 2 substituted with N-acetylglycine" [UniProtKB:P62491] xref: UniProtKB:P62491 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038438 ! RB11A_HUMAN [Term] id: CCO:B0039613 name: RB11B_HUMAN-N-acetylglycine2 def: "Protein RB11B_HUMAN with the residue 2 substituted with N-acetylglycine" [UniProtKB:Q15907] xref: UniProtKB:Q15907 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: transformation_of CCO:B0038434 ! RB11B_HUMAN [Term] id: CCO:B0039616 name: RGPS2_HUMAN-Phosphothreonine326 def: "Protein RGPS2_HUMAN with the residue 326 substituted with Phosphothreonine" [UniProtKB:Q86X27] xref: UniProtKB:Q86X27 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037994 ! RGPS2_HUMAN [Term] id: CCO:B0039617 name: RGPS2_HUMAN-Phosphoserine329 def: "Protein RGPS2_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q86X27] xref: UniProtKB:Q86X27 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037994 ! RGPS2_HUMAN [Term] id: CCO:B0039618 name: RGPS2_HUMAN-Phosphoserine343 def: "Protein RGPS2_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:Q86X27] xref: UniProtKB:Q86X27 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0037994 ! RGPS2_HUMAN [Term] id: CCO:B0039619 name: RHG05_HUMAN-Nitrated tyrosine550 def: "Protein RHG05_HUMAN with the residue 550 substituted with Nitrated tyrosine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0039620 name: RHOA_HUMAN-ADP-ribosylasparagine41 def: "Protein RHOA_HUMAN with the residue 41 substituted with ADP-ribosylasparagine" [UniProtKB:P61586] comment: by botulinum toxin; Probable xref: UniProtKB:P61586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020591 ! RHOA_HUMAN [Term] id: CCO:B0039621 name: RHOA_HUMAN-Cysteine methyl ester190 def: "Protein RHOA_HUMAN with the residue 190 substituted with Cysteine methyl ester" [UniProtKB:P61586] xref: UniProtKB:P61586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020591 ! RHOA_HUMAN [Term] id: CCO:B0039622 name: RHOC_HUMAN-Phosphothreonine19 def: "Protein RHOC_HUMAN with the residue 19 substituted with Phosphothreonine" [UniProtKB:P08134] comment: By similarity xref: UniProtKB:P08134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020594 ! RHOC_HUMAN [Term] id: CCO:B0039623 name: RHOC_HUMAN-Phosphoserine26 def: "Protein RHOC_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:P08134] comment: By similarity xref: UniProtKB:P08134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020594 ! RHOC_HUMAN [Term] id: CCO:B0039624 name: RHOC_HUMAN-ADP-ribosylasparagine41 def: "Protein RHOC_HUMAN with the residue 41 substituted with ADP-ribosylasparagine" [UniProtKB:P08134] comment: by botulinum toxin; By similarity xref: UniProtKB:P08134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020594 ! RHOC_HUMAN [Term] id: CCO:B0039625 name: RHOC_HUMAN-Cysteine methyl ester190 def: "Protein RHOC_HUMAN with the residue 190 substituted with Cysteine methyl ester" [UniProtKB:P08134] comment: By similarity xref: UniProtKB:P08134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020594 ! RHOC_HUMAN [Term] id: CCO:B0039631 name: RPB1_HUMAN-Phosphotyrosine145 def: "Protein RPB1_HUMAN with the residue 145 substituted with Phosphotyrosine" [UniProtKB:P24928] xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039632 name: RPB1_HUMAN-Phosphoserine772 def: "Protein RPB1_HUMAN with the residue 772 substituted with Phosphoserine" [UniProtKB:P24928] xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039633 name: RPB1_HUMAN-Phosphoserine777 def: "Protein RPB1_HUMAN with the residue 777 substituted with Phosphoserine" [UniProtKB:P24928] xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039634 name: RPB1_HUMAN-Phosphoserine1878 def: "Protein RPB1_HUMAN with the residue 1878 substituted with Phosphoserine" [UniProtKB:P24928] comment: By similarity xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039635 name: RPB1_HUMAN-Phosphoserine1896 def: "Protein RPB1_HUMAN with the residue 1896 substituted with Phosphoserine" [UniProtKB:P24928] xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039636 name: RPB1_HUMAN-Phosphotyrosine1923 def: "Protein RPB1_HUMAN with the residue 1923 substituted with Phosphotyrosine" [UniProtKB:P24928] comment: By similarity xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039637 name: RPB1_HUMAN-Phosphoserine1927 def: "Protein RPB1_HUMAN with the residue 1927 substituted with Phosphoserine" [UniProtKB:P24928] comment: By similarity xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039638 name: RPB1_HUMAN-Phosphothreonine1933 def: "Protein RPB1_HUMAN with the residue 1933 substituted with Phosphothreonine" [UniProtKB:P24928] comment: By similarity xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039639 name: RPB1_HUMAN-Phosphoserine1934 def: "Protein RPB1_HUMAN with the residue 1934 substituted with Phosphoserine" [UniProtKB:P24928] xref: UniProtKB:P24928 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:B0039640 name: RPGF1_HUMAN-Phosphoserine360 def: "Protein RPGF1_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q13905] xref: UniProtKB:Q13905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0038385 ! RPGF1_HUMAN [Term] id: CCO:B0039642 name: RRBP1_HUMAN-Phosphothreonine255 def: "Protein RRBP1_HUMAN with the residue 255 substituted with Phosphothreonine" [UniProtKB:Q9P2E9] xref: UniProtKB:Q9P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: transformation_of CCO:B0037300 ! RRBP1_HUMAN [Term] id: CCO:B0039643 name: RRBP1_HUMAN-Phosphothreonine275 def: "Protein RRBP1_HUMAN with the residue 275 substituted with Phosphothreonine" [UniProtKB:Q9P2E9] xref: UniProtKB:Q9P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037300 ! RRBP1_HUMAN [Term] id: CCO:B0039644 name: RRBP1_HUMAN-Phosphoserine533 def: "Protein RRBP1_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:Q9P2E9] xref: UniProtKB:Q9P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037300 ! RRBP1_HUMAN [Term] id: CCO:B0039645 name: RRBP1_HUMAN-Phosphoserine583 def: "Protein RRBP1_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:Q9P2E9] xref: UniProtKB:Q9P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037300 ! RRBP1_HUMAN [Term] id: CCO:B0039646 name: RRBP1_HUMAN-Phosphoserine615 def: "Protein RRBP1_HUMAN with the residue 615 substituted with Phosphoserine" [UniProtKB:Q9P2E9] xref: UniProtKB:Q9P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037300 ! RRBP1_HUMAN [Term] id: CCO:B0039648 name: SENP2_HUMAN-Phosphotyrosine216 def: "Protein SENP2_HUMAN with the residue 216 substituted with Phosphotyrosine" [UniProtKB:Q9HC62] xref: UniProtKB:Q9HC62 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036139 ! SENP2_HUMAN [Term] id: CCO:B0039654 name: SPHK2_HUMAN-Phosphoserine399 def: "Protein SPHK2_HUMAN with the residue 399 substituted with Phosphoserine" [UniProtKB:Q9NRA0] comment: By similarity xref: UniProtKB:Q9NRA0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001942 ! sphinganine kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003512 ! Ras GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0036431 ! SPHK2_HUMAN [Term] id: CCO:B0039660 name: STK38_HUMAN-Phosphothreonine26 def: "Protein STK38_HUMAN with the residue 26 substituted with Phosphothreonine" [UniProtKB:Q15208] xref: UniProtKB:Q15208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0015584 ! STK38_HUMAN [Term] id: CCO:B0039662 name: SYG_HUMAN-Phosphotyrosine453 def: "Protein SYG_HUMAN with the residue 453 substituted with Phosphotyrosine" [UniProtKB:P41250] comment: By similarity xref: UniProtKB:P41250 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001178 ! glycine-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000985 ! secretory granule relationship: transformation_of CCO:B0038779 ! SYG_HUMAN [Term] id: CCO:B0039664 name: SYUA_HUMAN-Phosphoserine87 def: "Protein SYUA_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:P37840] comment: by CK2; xref: UniProtKB:P37840 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: transformation_of CCO:B0018239 ! SYUA_HUMAN [Term] id: CCO:B0039665 name: SYUA_HUMAN-Phosphotyrosine125 def: "Protein SYUA_HUMAN with the residue 125 substituted with Phosphotyrosine" [UniProtKB:P37840] xref: UniProtKB:P37840 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018239 ! SYUA_HUMAN [Term] id: CCO:B0039666 name: SYUA_HUMAN-Phosphoserine129 def: "Protein SYUA_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:P37840] comment: by BARK1, CK2 and GRK5; xref: UniProtKB:P37840 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018239 ! SYUA_HUMAN [Term] id: CCO:B0039669 name: TALDO_HUMAN-Phosphoserine4 def: "Protein TALDO_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:P37837] xref: UniProtKB:P37837 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020161 ! TALDO_HUMAN [Term] id: CCO:B0039670 name: TALDO_HUMAN-Phosphoserine237 def: "Protein TALDO_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:P37837] comment: By similarity xref: UniProtKB:P37837 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001159 ! transaldolase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0020161 ! TALDO_HUMAN [Term] id: CCO:B0039671 name: TCTP_HUMAN-Phosphoserine46 def: "Protein TCTP_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:P13693] comment: by PLK1; xref: UniProtKB:P13693 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000354 ! multivesicular body relationship: located_in CCO:C0001946 ! tubulin complex relationship: transformation_of CCO:B0036188 ! TCTP_HUMAN [Term] id: CCO:B0039672 name: TCTP_HUMAN-Phosphoserine64 def: "Protein TCTP_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:P13693] comment: by PLK1; xref: UniProtKB:P13693 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036188 ! TCTP_HUMAN [Term] id: CCO:B0039673 name: TGFR1_HUMAN-Phosphothreonine185 def: "Protein TGFR1_HUMAN with the residue 185 substituted with Phosphothreonine" [UniProtKB:P36897] xref: UniProtKB:P36897 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020370 ! TGFR1_HUMAN [Term] id: CCO:B0039674 name: TGFR1_HUMAN-Phosphothreonine186 def: "Protein TGFR1_HUMAN with the residue 186 substituted with Phosphothreonine" [UniProtKB:P36897] xref: UniProtKB:P36897 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020370 ! TGFR1_HUMAN [Term] id: CCO:B0039675 name: TGFR1_HUMAN-Phosphoserine187 def: "Protein TGFR1_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:P36897] xref: UniProtKB:P36897 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020370 ! TGFR1_HUMAN [Term] id: CCO:B0039676 name: TGFR1_HUMAN-Phosphoserine189 def: "Protein TGFR1_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:P36897] xref: UniProtKB:P36897 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020370 ! TGFR1_HUMAN [Term] id: CCO:B0039677 name: TGFR1_HUMAN-Phosphoserine191 def: "Protein TGFR1_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:P36897] xref: UniProtKB:P36897 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001355 ! transforming growth factor beta receptor activity, type I relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007780 ! transforming growth factor beta binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001751 ! receptor complex relationship: transformation_of CCO:B0020370 ! TGFR1_HUMAN [Term] id: CCO:B0039678 name: TIF1A_HUMAN-Phosphoserine768 def: "Protein TIF1A_HUMAN with the residue 768 substituted with Phosphoserine" [UniProtKB:O15164] xref: UniProtKB:O15164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037051 ! TIF1A_HUMAN [Term] id: CCO:B0039679 name: TIF1A_HUMAN-Phosphoserine811 def: "Protein TIF1A_HUMAN with the residue 811 substituted with Phosphoserine" [UniProtKB:O15164] xref: UniProtKB:O15164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037051 ! TIF1A_HUMAN [Term] id: CCO:B0039682 name: TRPV1_HUMAN-Phosphoserine117 def: "Protein TRPV1_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039683 name: TRPV1_HUMAN-Phosphothreonine145 def: "Protein TRPV1_HUMAN with the residue 145 substituted with Phosphothreonine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039684 name: TRPV1_HUMAN-Phosphothreonine371 def: "Protein TRPV1_HUMAN with the residue 371 substituted with Phosphothreonine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039685 name: TRPV1_HUMAN-Phosphoserine502 def: "Protein TRPV1_HUMAN with the residue 502 substituted with Phosphoserine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039686 name: TRPV1_HUMAN-Phosphothreonine705 def: "Protein TRPV1_HUMAN with the residue 705 substituted with Phosphothreonine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039687 name: TRPV1_HUMAN-Phosphoserine775 def: "Protein TRPV1_HUMAN with the residue 775 substituted with Phosphoserine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039688 name: TRPV1_HUMAN-Phosphoserine801 def: "Protein TRPV1_HUMAN with the residue 801 substituted with Phosphoserine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039689 name: TRPV1_HUMAN-Phosphoserine821 def: "Protein TRPV1_HUMAN with the residue 821 substituted with Phosphoserine" [UniProtKB:Q8NER1] comment: By similarity xref: UniProtKB:Q8NER1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038932 ! TRPV1_HUMAN [Term] id: CCO:B0039693 name: TRPV4_HUMAN-Phosphotyrosine253 def: "Protein TRPV4_HUMAN with the residue 253 substituted with Phosphotyrosine" [UniProtKB:Q9HBA0] comment: By similarity xref: UniProtKB:Q9HBA0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038926 ! TRPV4_HUMAN [Term] id: CCO:B0039694 name: TTP_HUMAN-Phosphoserine60 def: "Protein TTP_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:P26651] comment: By similarity xref: UniProtKB:P26651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:B0039695 name: TTP_HUMAN-Phosphoserine88 def: "Protein TTP_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:P26651] comment: By similarity xref: UniProtKB:P26651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:B0039696 name: TTP_HUMAN-Phosphoserine90 def: "Protein TTP_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:P26651] comment: By similarity xref: UniProtKB:P26651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:B0039697 name: TTP_HUMAN-Phosphoserine93 def: "Protein TTP_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:P26651] comment: By similarity xref: UniProtKB:P26651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:B0039698 name: TTP_HUMAN-Phosphoserine186 def: "Protein TTP_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:P26651] comment: By similarity xref: UniProtKB:P26651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:B0039699 name: TTP_HUMAN-Phosphothreonine257 def: "Protein TTP_HUMAN with the residue 257 substituted with Phosphothreonine" [UniProtKB:P26651] comment: By similarity xref: UniProtKB:P26651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:B0039700 name: TTP_HUMAN-Phosphoserine323 def: "Protein TTP_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:P26651] comment: By similarity xref: UniProtKB:P26651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003558 ! AU-rich element binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:B0039710 name: ZBT40_HUMAN-Phosphoserine183 def: "Protein ZBT40_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0039711 name: ZBT40_HUMAN-Phosphoserine190 def: "Protein ZBT40_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0039712 name: ZBT40_HUMAN-Phosphoserine703 def: "Protein ZBT40_HUMAN with the residue 703 substituted with Phosphoserine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0039713 name: ZBT40_HUMAN-Phosphoserine728 def: "Protein ZBT40_HUMAN with the residue 728 substituted with Phosphoserine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0039714 name: ZF64A_HUMAN-Phosphothreonine473 def: "Protein ZF64A_HUMAN with the residue 473 substituted with Phosphothreonine" [UniProtKB:Q9NPA5] xref: UniProtKB:Q9NPA5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037139 ! ZF64A_HUMAN [Term] id: CCO:B0039715 name: ZF64A_HUMAN-Phosphoserine487 def: "Protein ZF64A_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:Q9NPA5] xref: UniProtKB:Q9NPA5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037139 ! ZF64A_HUMAN [Term] id: CCO:B0039716 name: ZN295_HUMAN-Phosphoserine361 def: "Protein ZN295_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039717 name: ZN295_HUMAN-Phosphoserine381 def: "Protein ZN295_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039718 name: ZN295_HUMAN-Phosphoserine411 def: "Protein ZN295_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039719 name: ZN295_HUMAN-Phosphoserine413 def: "Protein ZN295_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039720 name: ZN295_HUMAN-Phosphoserine422 def: "Protein ZN295_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039721 name: ZN295_HUMAN-Phosphoserine435 def: "Protein ZN295_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039722 name: ZN295_HUMAN-Phosphoserine714 def: "Protein ZN295_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039723 name: ZN295_HUMAN-Phosphoserine983 def: "Protein ZN295_HUMAN with the residue 983 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039724 name: ZN295_HUMAN-Phosphoserine1003 def: "Protein ZN295_HUMAN with the residue 1003 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0039725 name: ZN429_HUMAN-Phosphothreonine364 def: "Protein ZN429_HUMAN with the residue 364 substituted with Phosphothreonine" [UniProtKB:Q86V71] xref: UniProtKB:Q86V71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0037098 ! ZN429_HUMAN [Term] id: CCO:B0039756 name: FEN1_HUMAN def: "Flap endonuclease 1" [UniProtKB:P39748] synonym: "DNase IV" EXACT [UniProtKB:P39748] synonym: "EC 3.1.-.-" EXACT [UniProtKB:P39748] synonym: "FEN-1" EXACT [UniProtKB:P39748] synonym: "Flap structure-specific endonuclease 1" EXACT [UniProtKB:P39748] synonym: "hFEN-1" EXACT [UniProtKB:P39748] synonym: "Maturation factor 1" EXACT [UniProtKB:P39748] synonym: "MF1" EXACT [UniProtKB:P39748] xref: EMBL:AAA91331.1 xref: EMBL:AAC23394.1 xref: EMBL:AAH00323.1 xref: EMBL:AAM74238.1 xref: EMBL:CAA54166.1 xref: UniProtKB:P39748 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012898 ! FEN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008562 ! blm-fen1-2 physical interaction relationship: participates_in CCO:I0008563 ! blm-fen1-4 physical interaction relationship: participates_in CCO:I0008580 ! blm-fen1-1 direct interaction relationship: participates_in CCO:I0008583 ! blm-fen1-3 direct interaction relationship: participates_in CCO:I0015956 ! wrn-fen1-1 physical interaction relationship: participates_in CCO:I0015957 ! wrn-fen1-4 physical interaction relationship: participates_in CCO:I0017759 ! wrn-fen1-2 direct interaction relationship: participates_in CCO:I0017761 ! wrn-fen1-9 physical interaction relationship: participates_in CCO:I0018337 ! wrn-fen1-3 direct interaction relationship: participates_in CCO:I0018842 ! wrn-fen1-8 physical interaction relationship: participates_in CCO:I0018843 ! wrn-fen1-10 physical interaction relationship: participates_in CCO:I0019398 ! wrn-fen1-5 direct interaction relationship: participates_in CCO:I0019399 ! wrn-fen1-7 colocalization relationship: participates_in CCO:I0019651 ! arhgdia-fen1 physical interaction relationship: participates_in CCO:I0019715 ! fen1-eef1g physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0039763 ! FEN1_HUMAN-N6-acetyllysine354 relationship: transforms_into CCO:B0039764 ! FEN1_HUMAN-N6-acetyllysine375 relationship: transforms_into CCO:B0039765 ! FEN1_HUMAN-N6-acetyllysine377 relationship: transforms_into CCO:B0039766 ! FEN1_HUMAN-N6-acetyllysine380 [Term] id: CCO:B0039757 name: EXOS2_HUMAN def: "Exosome complex exonuclease RRP4" [UniProtKB:Q13868] synonym: "EC 3.1.13.-" EXACT [UniProtKB:Q13868] synonym: "Exosome component 2" EXACT [UniProtKB:Q13868] synonym: "Ribosomal RNA-processing protein 4" EXACT [UniProtKB:Q13868] xref: EMBL:AAB60392.1 xref: EMBL:AAH00747.1 xref: EMBL:BAA91977.1 xref: EMBL:BAB14043.1 xref: UniProtKB:Q13868 xref: UniProtKB:Q9NUY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0012897 ! EXOSC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008568 ! rrp4-rnf8 physical interaction relationship: participates_in CCO:I0015889 ! rrp4-znf408-1 physical interaction relationship: participates_in CCO:I0015896 ! znf408-rrp4 physical interaction relationship: participates_in CCO:I0017316 ! rrp4-znf408 physical interaction relationship: transforms_into CCO:B0039759 ! EXOS2_HUMAN-Phosphothreonine32 relationship: transforms_into CCO:B0039760 ! EXOS2_HUMAN-Phosphothreonine37 relationship: transforms_into CCO:B0039761 ! EXOS2_HUMAN-Phosphothreonine45 relationship: transforms_into CCO:B0039762 ! EXOS2_HUMAN-Phosphotyrosine46 relationship: transforms_into CCO:B0065184 ! EXOS2_HUMAN-Phosphoserine124 [Term] id: CCO:B0039758 name: UTP18_HUMAN def: "U3 small nucleolar RNA-associated protein 18 homolog" [UniProtKB:Q9Y5J1] synonym: "WD repeat-containing protein 50" EXACT [UniProtKB:Q9Y5J1] xref: EMBL:AAD34043.1 xref: EMBL:AAG01999.1 xref: EMBL:AAH25276.2 xref: UniProtKB:Q9H4N6 xref: UniProtKB:Q9Y5J1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0012900 ! UTP18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006305 ! mll-hcfc2-2 physical interaction relationship: participates_in CCO:I0008569 ! mll-hcfc2-1 physical interaction relationship: transforms_into CCO:B0039767 ! UTP18_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0039768 ! UTP18_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0039769 ! UTP18_HUMAN-Phosphoserine210 relationship: transforms_into CCO:B0048420 ! UTP18_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0048421 ! UTP18_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0071766 ! UTP18_HUMAN-Phosphothreonine204 [Term] id: CCO:B0039759 name: EXOS2_HUMAN-Phosphothreonine32 def: "Protein EXOS2_HUMAN with the residue 32 substituted with Phosphothreonine" [UniProtKB:Q13868] xref: UniProtKB:Q13868 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039757 ! EXOS2_HUMAN [Term] id: CCO:B0039760 name: EXOS2_HUMAN-Phosphothreonine37 def: "Protein EXOS2_HUMAN with the residue 37 substituted with Phosphothreonine" [UniProtKB:Q13868] xref: UniProtKB:Q13868 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039757 ! EXOS2_HUMAN [Term] id: CCO:B0039761 name: EXOS2_HUMAN-Phosphothreonine45 def: "Protein EXOS2_HUMAN with the residue 45 substituted with Phosphothreonine" [UniProtKB:Q13868] xref: UniProtKB:Q13868 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039757 ! EXOS2_HUMAN [Term] id: CCO:B0039762 name: EXOS2_HUMAN-Phosphotyrosine46 def: "Protein EXOS2_HUMAN with the residue 46 substituted with Phosphotyrosine" [UniProtKB:Q13868] xref: UniProtKB:Q13868 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000034 ! 3'-5'-exoribonuclease activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001826 ! 7S RNA binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000034 ! exosome (RNase complex) relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0039757 ! EXOS2_HUMAN [Term] id: CCO:B0039763 name: FEN1_HUMAN-N6-acetyllysine354 def: "Protein FEN1_HUMAN with the residue 354 substituted with N6-acetyllysine" [UniProtKB:P39748] xref: UniProtKB:P39748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:B0039764 name: FEN1_HUMAN-N6-acetyllysine375 def: "Protein FEN1_HUMAN with the residue 375 substituted with N6-acetyllysine" [UniProtKB:P39748] xref: UniProtKB:P39748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:B0039765 name: FEN1_HUMAN-N6-acetyllysine377 def: "Protein FEN1_HUMAN with the residue 377 substituted with N6-acetyllysine" [UniProtKB:P39748] xref: UniProtKB:P39748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001823 ! double-stranded DNA specific exodeoxyribonuclease activity relationship: has_function CCO:F0001876 ! 5'-3' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003572 ! 5'-flap endonuclease activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0007325 ! flap endonuclease activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:B0039766 name: FEN1_HUMAN-N6-acetyllysine380 def: "Protein FEN1_HUMAN with the residue 380 substituted with N6-acetyllysine" [UniProtKB:P39748] xref: UniProtKB:P39748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:B0039767 name: UTP18_HUMAN-Phosphoserine121 def: "Protein UTP18_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q9Y5J1] xref: UniProtKB:Q9Y5J1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:B0039768 name: UTP18_HUMAN-Phosphoserine124 def: "Protein UTP18_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q9Y5J1] xref: UniProtKB:Q9Y5J1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:B0039769 name: UTP18_HUMAN-Phosphoserine210 def: "Protein UTP18_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:Q9Y5J1] xref: UniProtKB:Q9Y5J1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000322 ! small nucleolar ribonucleoprotein complex relationship: transformation_of CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:B0039811 name: BIRC6_HUMAN def: "Baculoviral IAP repeat-containing protein 6" [UniProtKB:Q9NR09] synonym: "Ubiquitin-conjugating BIR domain enzyme apollon" EXACT [UniProtKB:Q9NR09] xref: EMBL:AAF75772.1 xref: EMBL:BAA86603.2 xref: UniProtKB:Q9NR09 xref: UniProtKB:Q9ULD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012905 ! BIRC6_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0063927 ! BIRC6_HUMAN-Phosphoserine452 [Term] id: CCO:B0039858 name: KLK8_HUMAN def: "Kallikrein-8 precursor" [UniProtKB:O60259] synonym: "EC 3.4.21.118" EXACT [UniProtKB:O60259] synonym: "hK8" EXACT [UniProtKB:O60259] synonym: "Neuropsin" EXACT [UniProtKB:O60259] synonym: "NP" EXACT [UniProtKB:O60259] synonym: "Ovasin" EXACT [UniProtKB:O60259] synonym: "Serine protease 19" EXACT [UniProtKB:O60259] synonym: "Serine protease TADG-14" EXACT [UniProtKB:O60259] synonym: "Tumor-associated differentially expressed gene 14 protein" EXACT [UniProtKB:O60259] xref: EMBL:AAD25979.1 xref: EMBL:AAD29574.1 xref: EMBL:AAD56050.1 xref: EMBL:AAF79144.1 xref: EMBL:AAF79145.1 xref: EMBL:AAG23254.1 xref: EMBL:AAG33361.1 xref: EMBL:AAH40887.1 xref: EMBL:AAQ89395.1 xref: EMBL:AAT76913.1 xref: EMBL:AAT76914.1 xref: EMBL:AAT76915.1 xref: EMBL:AAT76916.1 xref: EMBL:AAT76917.1 xref: EMBL:AAT76918.1 xref: EMBL:AAT76919.1 xref: EMBL:AAT76920.1 xref: EMBL:AAT76921.1 xref: EMBL:AAT76922.1 xref: EMBL:AAT76923.1 xref: EMBL:AAT76924.1 xref: EMBL:AAT76925.1 xref: EMBL:AAT76926.1 xref: EMBL:AAT76927.1 xref: EMBL:AAT76928.1 xref: EMBL:AAT76929.1 xref: EMBL:AAT76930.1 xref: EMBL:AAT76931.1 xref: EMBL:AAT76932.1 xref: EMBL:AAT76933.1 xref: EMBL:AAT76934.1 xref: EMBL:AAT76935.1 xref: EMBL:AAT76936.1 xref: EMBL:AAT76937.1 xref: EMBL:AAT76938.1 xref: EMBL:ABB83339.1 xref: EMBL:BAA28673.1 xref: EMBL:BAA28676.1 xref: EMBL:BAA82665.1 xref: EMBL:BAA82666.1 xref: EMBL:BAA88684.1 xref: EMBL:EAW71962.1 xref: UniProtKB:O60259 xref: UniProtKB:Q5V9X1 xref: UniProtKB:Q5V9X2 xref: UniProtKB:Q8IW69 xref: UniProtKB:Q9HCB3 xref: UniProtKB:Q9NR68 xref: UniProtKB:Q9NR69 xref: UniProtKB:Q9UIL9 xref: UniProtKB:Q9UQ47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012931 ! KLK8_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001480 ! negative regulation of myelination relationship: participates_in CCO:P0002248 ! keratinocyte proliferation relationship: participates_in CCO:P0002866 ! negative regulation of axon regeneration relationship: participates_in CCO:P0002961 ! regulation of synapse organization and biogenesis [Term] id: CCO:B0039862 name: KLK6_HUMAN def: "Kallikrein-6 precursor" [UniProtKB:Q92876] synonym: "EC 3.4.21.-" EXACT [UniProtKB:Q92876] synonym: "Neurosin" EXACT [UniProtKB:Q92876] synonym: "Protease M" EXACT [UniProtKB:Q92876] synonym: "Serine protease 18" EXACT [UniProtKB:Q92876] synonym: "Serine protease 9" EXACT [UniProtKB:Q92876] synonym: "SP59" EXACT [UniProtKB:Q92876] synonym: "Zyme" EXACT [UniProtKB:Q92876] xref: EMBL:AAB07113.1 xref: EMBL:AAB66483.1 xref: EMBL:AAD51475.1 xref: EMBL:AAG33359.1 xref: EMBL:AAH15525.1 xref: EMBL:AAP35498.1 xref: EMBL:AAP82446.1 xref: EMBL:AAP82448.1 xref: EMBL:ABB04464.1 xref: EMBL:BAA11306.1 xref: EMBL:BAG37411.1 xref: EMBL:EAW71953.1 xref: EMBL:EAW71954.1 xref: UniProtKB:A6NJA1 xref: UniProtKB:A8MW09 xref: UniProtKB:Q6H301 xref: UniProtKB:Q92876 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012929 ! KLK6_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000718 ! tissue kallikrein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000373 ! microsome relationship: participates_in CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:B0039886 name: RHEB_HUMAN def: "GTP-binding protein Rheb precursor" [UniProtKB:Q15382] synonym: "Ras homolog enriched in brain" EXACT [UniProtKB:Q15382] xref: EMBL:AAD15548.1 xref: EMBL:AAF73125.1 xref: EMBL:AAH16155.1 xref: EMBL:AAI07706.1 xref: EMBL:AAM12635.1 xref: EMBL:AAP35604.1 xref: EMBL:BAA11211.1 xref: EMBL:CAA82774.1 xref: UniProtKB:Q15382 xref: UniProtKB:Q53Y56 xref: UniProtKB:Q99444 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012944 ! RHEB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0039936 ! RHEB_HUMAN-Cysteine methyl ester181 [Term] id: CCO:B0039905 name: TLE6_HUMAN def: "Transducin-like enhancer protein 6" [UniProtKB:Q9H808] xref: EMBL:AAH07215.1 xref: EMBL:AAH20206.1 xref: EMBL:BAB14815.1 xref: UniProtKB:Q9H808 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012947 ! TLE6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0039910 name: A8MSP9_HUMAN def: "Putative uncharacterized protein TLE4" [UniProtKB:A8MSP9] xref: UniProtKB:A8MSP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012946 ! TLE4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0039914 name: TR13B_HUMAN def: "Tumor necrosis factor receptor superfamily member 13B" [UniProtKB:O14836] synonym: "CD267 antigen" EXACT [UniProtKB:O14836] synonym: "Transmembrane activator and CAML interactor" EXACT [UniProtKB:O14836] xref: EMBL:AAC51790.1 xref: EMBL:AAP57629.1 xref: UniProtKB:O14836 xref: UniProtKB:Q7Z6F5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012948 ! TNFRSF13B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017363 ! tac1-blys-3 physical interaction relationship: participates_in CCO:I0017364 ! tac1-april physical interaction relationship: participates_in CCO:I0017365 ! tac1-ztnf4 physical interaction relationship: participates_in CCO:I0017502 ! tac1-tall_1 physical interaction relationship: participates_in CCO:I0017503 ! tac1-tall_1-1 physical interaction relationship: participates_in CCO:I0017869 ! tac1-blys-2 physical interaction relationship: participates_in CCO:I0018020 ! tac1-blys-4 direct interaction relationship: participates_in CCO:I0018492 ! tac1-blys physical interaction relationship: participates_in CCO:I0019359 ! tac1-blys-1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001352 ! negative regulation of B cell proliferation [Term] id: CCO:B0039927 name: K1C20_HUMAN-Phosphoserine13 def: "Protein K1C20_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P35900] comment: by PKC; xref: UniProtKB:P35900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0023749 ! K1C20_HUMAN [Term] id: CCO:B0039928 name: K1C20_HUMAN-Phosphoserine14 def: "Protein K1C20_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:P35900] comment: By similarity xref: UniProtKB:P35900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023749 ! K1C20_HUMAN [Term] id: CCO:B0039929 name: K1C20_HUMAN-Phosphoserine34 def: "Protein K1C20_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P35900] xref: UniProtKB:P35900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023749 ! K1C20_HUMAN [Term] id: CCO:B0039936 name: RHEB_HUMAN-Cysteine methyl ester181 def: "Protein RHEB_HUMAN with the residue 181 substituted with Cysteine methyl ester" [UniProtKB:Q15382] comment: Probable xref: UniProtKB:Q15382 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0039886 ! RHEB_HUMAN [Term] id: CCO:B0039937 name: TLE4_HUMAN-Phosphoserine250 def: "Protein TLE4_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:Q04727] comment: by CK2; Potential xref: UniProtKB:Q04727 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016924 ! TLE4_HUMAN [Term] id: CCO:B0039938 name: TLE4_HUMAN-Phosphoserine265 def: "Protein TLE4_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q04727] comment: by CDC2; Potential xref: UniProtKB:Q04727 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0016924 ! TLE4_HUMAN [Term] id: CCO:B0039945 name: CRBL2_HUMAN def: "cAMP-responsive element-binding protein-like 2" [UniProtKB:O60519] xref: EMBL:AAC32314.1 xref: EMBL:AAI04874.1 xref: EMBL:AAI06053.1 xref: EMBL:AAI12158.1 xref: EMBL:CAG47046.1 xref: EMBL:EAW96269.1 xref: UniProtKB:O60519 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012992 ! CREBL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0039946 name: NPAT_HUMAN def: "Protein NPAT" [UniProtKB:Q14207] synonym: "Nuclear protein of the ataxia telangiectasia mutated locus" EXACT [UniProtKB:Q14207] synonym: "Nuclear protein of the ATM locus" EXACT [UniProtKB:Q14207] synonym: "p220" EXACT [UniProtKB:Q14207] xref: EMBL:AAB02735.1 xref: EMBL:AAH40356.1 xref: EMBL:AAH50561.1 xref: EMBL:BAA11861.1 xref: EMBL:BAA21367.1 xref: EMBL:BAF82709.1 xref: EMBL:BAF84376.1 xref: EMBL:CAA65824.1 xref: UniProtKB:A8K1V5 xref: UniProtKB:A8K6M2 xref: UniProtKB:Q13632 xref: UniProtKB:Q14207 xref: UniProtKB:Q14967 xref: UniProtKB:Q16580 xref: UniProtKB:Q86W55 xref: UniProtKB:Q8IWE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012995 ! NPAT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0039951 ! NPAT_HUMAN-Phosphoserine535 relationship: transforms_into CCO:B0039952 ! NPAT_HUMAN-Phosphoserine775 relationship: transforms_into CCO:B0039953 ! NPAT_HUMAN-Phosphoserine779 relationship: transforms_into CCO:B0039954 ! NPAT_HUMAN-Phosphoserine1100 relationship: transforms_into CCO:B0039955 ! NPAT_HUMAN-Phosphothreonine1270 relationship: transforms_into CCO:B0039956 ! NPAT_HUMAN-Phosphothreonine1350 [Term] id: CCO:B0039947 name: STRA8_HUMAN def: "Stimulated by retinoic acid gene 8 protein homolog" [UniProtKB:Q7Z7C7] xref: EMBL:AAP47163.1 xref: EMBL:EAL24061.1 xref: EMBL:EAW83846.1 xref: UniProtKB:Q7Z7C7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012996 ! STRA8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0039948 name: ZFP42_HUMAN def: "Zinc finger protein 42 homolog" [UniProtKB:Q96MM3] synonym: "hREX-1" EXACT [UniProtKB:Q96MM3] synonym: "Reduced expression protein 1" EXACT [UniProtKB:Q96MM3] synonym: "REX-1" EXACT [UniProtKB:Q96MM3] synonym: "Zfp-42" EXACT [UniProtKB:Q96MM3] synonym: "Zinc finger protein 754" EXACT [UniProtKB:Q96MM3] xref: EMBL:AAL47167.1 xref: EMBL:AAR07993.1 xref: EMBL:BAB71264.1 xref: UniProtKB:Q8WXE2 xref: UniProtKB:Q96MM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012997 ! ZFP42_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000117 ! meiosis relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0039949 name: FSD1_HUMAN def: "Fibronectin type III and SPRY domain-containing protein 1" [UniProtKB:Q9BTV5] synonym: "Microtubule-associated protein GLFND" EXACT [UniProtKB:Q9BTV5] synonym: "MID1-related protein 1" EXACT [UniProtKB:Q9BTV5] xref: EMBL:AAH03124.1 xref: EMBL:AAK26747.1 xref: EMBL:AAK51145.1 xref: EMBL:BAB13885.1 xref: UniProtKB:Q9BTV5 xref: UniProtKB:Q9BXN0 xref: UniProtKB:Q9HAG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012994 ! FSD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0008654 ! ppp1r16a-fsd1 physical interaction relationship: participates_in CCO:I0008655 ! nap1l1-fsd1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0039950 name: DCC1_HUMAN def: "Sister chromatid cohesion protein DCC1" [UniProtKB:Q9BVC3] synonym: "Defective in sister chromatid cohesion protein 1 homolog" EXACT [UniProtKB:Q9BVC3] xref: EMBL:AAH01316.1 xref: EMBL:AAH01531.1 xref: EMBL:AAQ89225.1 xref: EMBL:BAB70767.1 xref: UniProtKB:Q969N5 xref: UniProtKB:Q9BVC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013374 ! DSCC1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0039951 name: NPAT_HUMAN-Phosphoserine535 def: "Protein NPAT_HUMAN with the residue 535 substituted with Phosphoserine" [UniProtKB:Q14207] xref: UniProtKB:Q14207 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039946 ! NPAT_HUMAN [Term] id: CCO:B0039952 name: NPAT_HUMAN-Phosphoserine775 def: "Protein NPAT_HUMAN with the residue 775 substituted with Phosphoserine" [UniProtKB:Q14207] comment: by CDK2; xref: UniProtKB:Q14207 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039946 ! NPAT_HUMAN [Term] id: CCO:B0039953 name: NPAT_HUMAN-Phosphoserine779 def: "Protein NPAT_HUMAN with the residue 779 substituted with Phosphoserine" [UniProtKB:Q14207] comment: by CDK2; xref: UniProtKB:Q14207 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039946 ! NPAT_HUMAN [Term] id: CCO:B0039954 name: NPAT_HUMAN-Phosphoserine1100 def: "Protein NPAT_HUMAN with the residue 1100 substituted with Phosphoserine" [UniProtKB:Q14207] comment: by CDK2; xref: UniProtKB:Q14207 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039946 ! NPAT_HUMAN [Term] id: CCO:B0039955 name: NPAT_HUMAN-Phosphothreonine1270 def: "Protein NPAT_HUMAN with the residue 1270 substituted with Phosphothreonine" [UniProtKB:Q14207] comment: by CDK2; xref: UniProtKB:Q14207 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0039946 ! NPAT_HUMAN [Term] id: CCO:B0039956 name: NPAT_HUMAN-Phosphothreonine1350 def: "Protein NPAT_HUMAN with the residue 1350 substituted with Phosphothreonine" [UniProtKB:Q14207] comment: by CDK2; xref: UniProtKB:Q14207 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039946 ! NPAT_HUMAN [Term] id: CCO:B0039979 name: PP16A_HUMAN def: "Protein phosphatase 1 regulatory subunit 16A" [UniProtKB:Q96I34] synonym: "Myosin phosphatase-targeting subunit 3" EXACT [UniProtKB:Q96I34] xref: EMBL:AAH07854.1 xref: EMBL:AAH49841.1 xref: EMBL:AAH53506.1 xref: EMBL:AAP35491.1 xref: EMBL:BAC03452.1 xref: UniProtKB:Q96I34 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013022 ! PPP1R16A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008654 ! ppp1r16a-fsd1 physical interaction relationship: participates_in CCO:I0015690 ! ppp1r16a-trip6 physical interaction relationship: participates_in CCO:I0020119 ! ppp1r16a-txnrd1 physical interaction relationship: transforms_into CCO:B0039988 ! PP16A_HUMAN-Phosphotyrosine434 [Term] id: CCO:B0039988 name: PP16A_HUMAN-Phosphotyrosine434 def: "Protein PP16A_HUMAN with the residue 434 substituted with Phosphotyrosine" [UniProtKB:Q96I34] comment: By similarity xref: UniProtKB:Q96I34 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0039979 ! PP16A_HUMAN [Term] id: CCO:B0040018 name: GNPAT_HUMAN def: "Dihydroxyacetone phosphate acyltransferase" [UniProtKB:O15228] synonym: "Acyl-CoA:dihydroxyacetonephosphateacyltransferase" EXACT [UniProtKB:O15228] synonym: "DAP-AT" EXACT [UniProtKB:O15228] synonym: "DHAP-AT" EXACT [UniProtKB:O15228] synonym: "EC 2.3.1.42" EXACT [UniProtKB:O15228] synonym: "Glycerone-phosphate O-acyltransferase" EXACT [UniProtKB:O15228] xref: EMBL:AAC24505.1 xref: EMBL:AAG17547.1 xref: EMBL:AAH00450.1 xref: EMBL:CAA05242.1 xref: EMBL:CAI21988.1 xref: EMBL:CAI23094.1 xref: UniProtKB:O15228 xref: UniProtKB:Q5TBH7 xref: UniProtKB:Q9BWC2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013027 ! GNPAT_human relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003104 ! glycerone-phosphate O-acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020642 ! rab35-gnpat physical interaction [Term] id: CCO:B0040022 name: JMY_HUMAN def: "Junction-mediating and -regulatory protein" [UniProtKB:Q8N9B5] xref: EMBL:AAI30625.1 xref: EMBL:BAC04495.1 xref: EMBL:EAW95834.1 xref: UniProtKB:A1L4P5 xref: UniProtKB:Q8N9B5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006025 ! JMY_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007362 ! p53-jmy-1 physical interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0003022 ! positive regulation of transcription factor activity relationship: transforms_into CCO:B0048299 ! JMY_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0067221 ! JMY_HUMAN-Phosphoserine974 [Term] id: CCO:B0040082 name: UBP8_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 8" [UniProtKB:P40818] synonym: "Deubiquitinating enzyme 8" EXACT [UniProtKB:P40818] synonym: "EC 3.1.2.15" EXACT [UniProtKB:P40818] synonym: "hUBPy" EXACT [UniProtKB:P40818] synonym: "Ubiquitin thioesterase 8" EXACT [UniProtKB:P40818] synonym: "Ubiquitin-specific-processing protease 8" EXACT [UniProtKB:P40818] xref: EMBL:AAH38801.1 xref: EMBL:AAH51345.1 xref: EMBL:AAI10591.1 xref: EMBL:BAA06225.2 xref: EMBL:CAD97662.1 xref: UniProtKB:P40818 xref: UniProtKB:Q2TB31 xref: UniProtKB:Q7Z3U2 xref: UniProtKB:Q86VA0 xref: UniProtKB:Q8IWI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013134 ! USP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0040663 ! UBP8_HUMAN-Phosphoserine434 relationship: transforms_into CCO:B0071700 ! UBP8_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0071701 ! UBP8_HUMAN-Phosphoserine718 relationship: transforms_into CCO:B0071702 ! UBP8_HUMAN-Phosphoserine719 [Term] id: CCO:B0040086 name: SYT17_HUMAN def: "Synaptotagmin-17" [UniProtKB:Q9BSW7] synonym: "Protein B/K" EXACT [UniProtKB:Q9BSW7] synonym: "Synaptotagmin XVII" EXACT [UniProtKB:Q9BSW7] synonym: "SytXVII" EXACT [UniProtKB:Q9BSW7] xref: EMBL:AAC05436.1 xref: EMBL:AAF37825.1 xref: EMBL:AAH04518.1 xref: EMBL:EAW50274.1 xref: UniProtKB:O43330 xref: UniProtKB:Q9BSW7 xref: UniProtKB:Q9NZ18 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013125 ! SYT17_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015657 ! syt17-tsc22d4 physical interaction relationship: participates_in CCO:I0018911 ! aptx-syt17 physical interaction [Term] id: CCO:B0040093 name: SYT5_HUMAN def: "Synaptotagmin-5" [UniProtKB:O00445] synonym: "Synaptotagmin V" EXACT [UniProtKB:O00445] synonym: "SytV" EXACT [UniProtKB:O00445] xref: EMBL:AAH46157.1 xref: EMBL:CAA65579.1 xref: UniProtKB:O00445 xref: UniProtKB:Q86X72 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013129 ! SYT5_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002023 ! recycling endosome membrane relationship: participates_in CCO:I0020639 ! rab1a-syt5 physical interaction relationship: transforms_into CCO:B0040658 ! SYT5_HUMAN-Phosphotyrosine278 [Term] id: CCO:B0040103 name: SYT1_HUMAN def: "Synaptotagmin-1" [UniProtKB:P21579] synonym: "p65" EXACT [UniProtKB:P21579] synonym: "Synaptotagmin I" EXACT [UniProtKB:P21579] synonym: "SytI" EXACT [UniProtKB:P21579] xref: EMBL:AAA60609.1 xref: EMBL:AAH58917.1 xref: UniProtKB:P21579 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013126 ! SYT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016276 ! stn2-syt1-1 colocalization relationship: participates_in CCO:I0017974 ! cacnb3-syt1-1 physical interaction relationship: participates_in CCO:I0018037 ! hip14-syt1-1 palmitoylation relationship: transforms_into CCO:B0040654 ! SYT1_HUMAN-Phosphothreonine129 relationship: transforms_into CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: transforms_into CCO:B0040656 ! SYT1_HUMAN-Phosphotyrosine365 relationship: transforms_into CCO:B0040657 ! SYT1_HUMAN-Phosphotyrosine381 [Term] id: CCO:B0040141 name: B0I1T6_HUMAN def: "MYO9B variant protein" [UniProtKB:B0I1T6] xref: EMBL:BAG06734.1 xref: UniProtKB:B0I1T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000788 ! myosin complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0040243 name: PGK1_HUMAN def: "Phosphoglycerate kinase 1" [UniProtKB:P00558] synonym: "Cell migration-inducing gene 10 protein" EXACT [UniProtKB:P00558] synonym: "EC 2.7.2.3" EXACT [UniProtKB:P00558] synonym: "Primer recognition protein 2" EXACT [UniProtKB:P00558] synonym: "PRP 2" EXACT [UniProtKB:P00558] xref: EMBL:AAA60078.1 xref: EMBL:AAA60079.1 xref: EMBL:AAA60103.1 xref: EMBL:AAH23234.1 xref: EMBL:AAI03753.1 xref: EMBL:AAI04838.1 xref: EMBL:AAI13569.1 xref: EMBL:AAS00488.1 xref: EMBL:BAB93495.1 xref: EMBL:CAA23835.1 xref: EMBL:CAG32997.1 xref: EMBL:CAI42951.1 xref: UniProtKB:P00558 xref: UniProtKB:Q5J7W1 xref: UniProtKB:Q6IBT6 xref: UniProtKB:Q8NI87 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013113 ! PGK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: transforms_into CCO:B0040641 ! PGK1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0040642 ! PGK1_HUMAN-Phosphotyrosine76 relationship: transforms_into CCO:B0040643 ! PGK1_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0040644 ! PGK1_HUMAN-Phosphotyrosine196 relationship: transforms_into CCO:B0040645 ! PGK1_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0040646 ! PGK1_HUMAN-Phosphothreonine243 relationship: transforms_into CCO:B0040647 ! PGK1_HUMAN-Phosphoserine390 [Term] id: CCO:B0040253 name: IMA4_HUMAN def: "Importin subunit alpha-4" [UniProtKB:O00629] synonym: "Importin alpha Q1" EXACT [UniProtKB:O00629] synonym: "Karyopherin subunit alpha-4" EXACT [UniProtKB:O00629] synonym: "Qip1" EXACT [UniProtKB:O00629] xref: EMBL:AAC25605.1 xref: EMBL:AAH28691.1 xref: EMBL:AAH34493.1 xref: EMBL:BAA19546.1 xref: EMBL:CAA73025.1 xref: UniProtKB:O00190 xref: UniProtKB:O00629 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013100 ! KPNA4_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: transforms_into CCO:B0040622 ! IMA4_HUMAN-Phosphoserine60 [Term] id: CCO:B0040310 name: RF1M_HUMAN def: "Peptide chain release factor 1, mitochondrial precursor" [UniProtKB:O75570] synonym: "MRF-1" EXACT [UniProtKB:O75570] xref: EMBL:AAD12759.1 xref: EMBL:AAH42196.1 xref: EMBL:CAI16615.1 xref: EMBL:CAI16617.1 xref: UniProtKB:O75570 xref: UniProtKB:Q5T6Y5 xref: UniProtKB:Q8IUQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013120 ! MTRF1_human relationship: has_function CCO:F0000318 ! translation release factor activity relationship: has_function CCO:F0003040 ! translation release factor activity, codon specific relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000664 ! regulation of translational termination [Term] id: CCO:B0040367 name: MYO1F_HUMAN def: "Myosin-If" [UniProtKB:O00160] synonym: "Myosin-Ie" EXACT [UniProtKB:O00160] xref: EMBL:AAH28071.1 xref: EMBL:BAC03995.1 xref: EMBL:CAA67058.1 xref: EMBL:CAC83948.1 xref: UniProtKB:O00160 xref: UniProtKB:Q8WWN7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013108 ! MYO1F_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0000790 ! unconventional myosin complex relationship: participates_in CCO:I0015014 ! ewsr1-myo1f physical interaction relationship: transforms_into CCO:B0040636 ! MYO1F_HUMAN-Phosphoserine734 [Term] id: CCO:B0040425 name: MDN1_HUMAN def: "Midasin" [UniProtKB:Q9NU22] synonym: "MIDAS-containing protein" EXACT [UniProtKB:Q9NU22] xref: EMBL:AAM77722.1 xref: EMBL:BAA20761.2 xref: EMBL:CAI42279.1 xref: UniProtKB:O15019 xref: UniProtKB:Q9NU22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013103 ! MDN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002176 ! regulation of protein complex assembly relationship: transforms_into CCO:B0040631 ! MDN1_HUMAN-Phosphoserine4538 relationship: transforms_into CCO:B0040632 ! MDN1_HUMAN-Phosphoserine4752 relationship: transforms_into CCO:B0040633 ! MDN1_HUMAN-Phosphoserine4754 relationship: transforms_into CCO:B0040634 ! MDN1_HUMAN-Phosphothreonine4898 relationship: transforms_into CCO:B0040635 ! MDN1_HUMAN-Phosphoserine5015 [Term] id: CCO:B0040467 name: CASP1_HUMAN def: "Caspase-1 precursor" [UniProtKB:P29466] synonym: "CASP-1" EXACT [UniProtKB:P29466] synonym: "EC 3.4.22.36" EXACT [UniProtKB:P29466] synonym: "ICE" EXACT [UniProtKB:P29466] synonym: "IL-1 beta-converting enzyme" EXACT [UniProtKB:P29466] synonym: "IL-1BC" EXACT [UniProtKB:P29466] synonym: "Interleukin-1 beta convertase" EXACT [UniProtKB:P29466] synonym: "Interleukin-1 beta-converting enzyme" EXACT [UniProtKB:P29466] synonym: "p45" EXACT [UniProtKB:P29466] xref: EMBL:AAA66942.1 xref: EMBL:AAC50107.1 xref: EMBL:AAC50108.1 xref: EMBL:AAC50109.1 xref: EMBL:AAC50110.1 xref: EMBL:AAH41689.1 xref: EMBL:AAH62327.1 xref: EMBL:AAT72297.1 xref: EMBL:BAD97223.1 xref: EMBL:CAA46153.1 xref: UniProtKB:P29466 xref: UniProtKB:Q53EY6 xref: UniProtKB:Q6DMQ1 xref: UniProtKB:Q6GSS3 xref: UniProtKB:Q6PI75 xref: UniProtKB:Q9UCN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013082 ! CASP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0040469 name: Q5FBZ0_HUMAN def: "CASP1 nirs variant 1" [UniProtKB:Q5FBZ0] xref: EMBL:BAD89407.1 xref: UniProtKB:Q5FBZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013082 ! CASP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040471 name: CASP4_HUMAN def: "Caspase-4 precursor" [UniProtKB:P49662] synonym: "CASP-4" EXACT [UniProtKB:P49662] synonym: "EC 3.4.22.57" EXACT [UniProtKB:P49662] synonym: "ICE(rel)-II" EXACT [UniProtKB:P49662] synonym: "ICH-2 protease" EXACT [UniProtKB:P49662] synonym: "TX protease" EXACT [UniProtKB:P49662] xref: EMBL:AAA75171.1 xref: EMBL:AAA86890.1 xref: EMBL:AAH17839.1 xref: EMBL:CAA88750.1 xref: UniProtKB:P49662 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013083 ! CASP4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0064075 ! CASP4_HUMAN-Phosphoserine83 [Term] id: CCO:B0040472 name: INCA_HUMAN def: "Caspase-1 inhibitor INCA" [UniProtKB:Q5XLA6] synonym: "Inhibitory caspase recruitment domain protein" EXACT [UniProtKB:Q5XLA6] xref: EMBL:AAV28630.1 xref: UniProtKB:Q5XLA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013157 ! INCA_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040474 name: ICBR_HUMAN def: "Caspase-1 inhibitor Iceberg" [UniProtKB:P57730] xref: EMBL:AAG23528.1 xref: EMBL:AAQ88598.1 xref: UniProtKB:P57730 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013099 ! ICEBERG_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040476 name: O95601_HUMAN def: "Mih1/Tx protein" [UniProtKB:O95601] xref: EMBL:AAC99853.1 xref: UniProtKB:O95601 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013139 ! mih1/Tx_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040477 name: Q0QVY8_HUMAN def: "Caspase-5/e" [UniProtKB:Q0QVY8] xref: EMBL:ABB58702.1 xref: UniProtKB:Q0QVY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040479 name: Q0QVY7_HUMAN def: "Caspase-5/f" [UniProtKB:Q0QVY7] xref: EMBL:ABB58703.1 xref: UniProtKB:Q0QVY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040484 name: CASP5_HUMAN def: "Caspase-5 precursor" [UniProtKB:P51878] synonym: "CASP-5" EXACT [UniProtKB:P51878] synonym: "EC 3.4.22.58" EXACT [UniProtKB:P51878] synonym: "ICE(rel)-III" EXACT [UniProtKB:P51878] synonym: "ICH-3 protease" EXACT [UniProtKB:P51878] synonym: "TY protease" EXACT [UniProtKB:P51878] xref: EMBL:AAA75172.1 xref: EMBL:CAA64450.1 xref: UniProtKB:P51878 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013084 ! CASP5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040485 name: CASPC_HUMAN def: "Inactive caspase-12" [UniProtKB:Q6UXS9] synonym: "CASP-12" EXACT [UniProtKB:Q6UXS9] xref: EMBL:AAQ88589.1 xref: UniProtKB:Q6UXS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013085 ! CASP12_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040488 name: Q96RJ9_HUMAN xref: UniProtKB:Q96RJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040491 name: COP_HUMAN def: "Caspase-1 inhibitor COP" [UniProtKB:Q5EG05] synonym: "CARD only domain-containing protein 1" EXACT [UniProtKB:Q5EG05] synonym: "Pseudo interleukin-1 beta converting enzyme" EXACT [UniProtKB:Q5EG05] synonym: "Pseudo-ICE" EXACT [UniProtKB:Q5EG05] xref: EMBL:AAI17479.1 xref: EMBL:AAI17481.1 xref: EMBL:AAK71682.1 xref: EMBL:AAW78563.1 xref: EMBL:BAG34843.1 xref: EMBL:EAW67062.1 xref: UniProtKB:Q5EG05 xref: UniProtKB:Q96RJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013152 ! COP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0040516 name: RS14_HUMAN def: "40S ribosomal protein S14" [UniProtKB:P62263] xref: EMBL:AAB59505.1 xref: EMBL:AAF71130.1 xref: EMBL:AAH01126.1 xref: EMBL:AAH03401.1 xref: EMBL:AAH06784.1 xref: EMBL:AAH20515.1 xref: EMBL:AAH91474.1 xref: UniProtKB:P06366 xref: UniProtKB:P62263 xref: UniProtKB:Q5BJI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013121 ! RPS14_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015358 ! rps14-taf9 physical interaction relationship: participates_in CCO:I0016525 ! ikbkg-rps14 physical interaction relationship: participates_in CCO:I0016620 ! map3k1-rps14 physical interaction relationship: participates_in CCO:I0016804 ! nfkb2-rps14 physical interaction relationship: participates_in CCO:I0016873 ! relb-rps14 physical interaction relationship: participates_in CCO:I0017045 ! tnfrsf1b-rps14 physical interaction relationship: participates_in CCO:I0017588 ! rps14-taf9-1 physical interaction relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0040651 ! RS14_HUMAN-Phosphothreonine140 relationship: transforms_into CCO:B0043360 ! RS14_HUMAN-Phosphothreonine105 relationship: transforms_into CCO:B0043361 ! RS14_HUMAN-Phosphothreonine107 [Term] id: CCO:B0040520 name: A9UJN9_HUMAN def: "Platelet-derived growth factor beta polypeptide (Simian sarcoma viral (V-sis) oncogene homolog)" [UniProtKB:A9UJN9] xref: EMBL:CAP58850.1 xref: UniProtKB:A9UJN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005288 ! PDGFB_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0040622 name: IMA4_HUMAN-Phosphoserine60 def: "Protein IMA4_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:O00629] xref: UniProtKB:O00629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040253 ! IMA4_HUMAN [Term] id: CCO:B0040623 name: ITSN1_HUMAN-Phosphoserine313 def: "Protein ITSN1_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q15811] comment: By similarity xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040624 name: ITSN1_HUMAN-Phosphoserine315 def: "Protein ITSN1_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q15811] comment: By similarity xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040625 name: ITSN1_HUMAN-Phosphoserine318 def: "Protein ITSN1_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q15811] comment: By similarity xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040626 name: ITSN1_HUMAN-Phosphoserine559 def: "Protein ITSN1_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:Q15811] xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040627 name: ITSN1_HUMAN-Phosphoserine902 def: "Protein ITSN1_HUMAN with the residue 902 substituted with Phosphoserine" [UniProtKB:Q15811] xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040628 name: ITSN1_HUMAN-Phosphoserine904 def: "Protein ITSN1_HUMAN with the residue 904 substituted with Phosphoserine" [UniProtKB:Q15811] xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040629 name: ITSN1_HUMAN-Phosphothreonine977 def: "Protein ITSN1_HUMAN with the residue 977 substituted with Phosphothreonine" [UniProtKB:Q15811] comment: By similarity xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040630 name: ITSN1_HUMAN-Phosphoserine1137 def: "Protein ITSN1_HUMAN with the residue 1137 substituted with Phosphoserine" [UniProtKB:Q15811] comment: By similarity xref: UniProtKB:Q15811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:B0040631 name: MDN1_HUMAN-Phosphoserine4538 def: "Protein MDN1_HUMAN with the residue 4538 substituted with Phosphoserine" [UniProtKB:Q9NU22] xref: UniProtKB:Q9NU22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0040425 ! MDN1_HUMAN [Term] id: CCO:B0040632 name: MDN1_HUMAN-Phosphoserine4752 def: "Protein MDN1_HUMAN with the residue 4752 substituted with Phosphoserine" [UniProtKB:Q9NU22] xref: UniProtKB:Q9NU22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040425 ! MDN1_HUMAN [Term] id: CCO:B0040633 name: MDN1_HUMAN-Phosphoserine4754 def: "Protein MDN1_HUMAN with the residue 4754 substituted with Phosphoserine" [UniProtKB:Q9NU22] xref: UniProtKB:Q9NU22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040425 ! MDN1_HUMAN [Term] id: CCO:B0040634 name: MDN1_HUMAN-Phosphothreonine4898 def: "Protein MDN1_HUMAN with the residue 4898 substituted with Phosphothreonine" [UniProtKB:Q9NU22] xref: UniProtKB:Q9NU22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040425 ! MDN1_HUMAN [Term] id: CCO:B0040635 name: MDN1_HUMAN-Phosphoserine5015 def: "Protein MDN1_HUMAN with the residue 5015 substituted with Phosphoserine" [UniProtKB:Q9NU22] xref: UniProtKB:Q9NU22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040425 ! MDN1_HUMAN [Term] id: CCO:B0040636 name: MYO1F_HUMAN-Phosphoserine734 def: "Protein MYO1F_HUMAN with the residue 734 substituted with Phosphoserine" [UniProtKB:O00160] xref: UniProtKB:O00160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040367 ! MYO1F_HUMAN [Term] id: CCO:B0040641 name: PGK1_HUMAN-N-acetylserine2 def: "Protein PGK1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P00558] xref: UniProtKB:P00558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040243 ! PGK1_HUMAN [Term] id: CCO:B0040642 name: PGK1_HUMAN-Phosphotyrosine76 def: "Protein PGK1_HUMAN with the residue 76 substituted with Phosphotyrosine" [UniProtKB:P00558] comment: By similarity xref: UniProtKB:P00558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040243 ! PGK1_HUMAN [Term] id: CCO:B0040643 name: PGK1_HUMAN-Phosphoserine136 def: "Protein PGK1_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:P00558] xref: UniProtKB:P00558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040243 ! PGK1_HUMAN [Term] id: CCO:B0040644 name: PGK1_HUMAN-Phosphotyrosine196 def: "Protein PGK1_HUMAN with the residue 196 substituted with Phosphotyrosine" [UniProtKB:P00558] xref: UniProtKB:P00558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040243 ! PGK1_HUMAN [Term] id: CCO:B0040645 name: PGK1_HUMAN-Phosphoserine203 def: "Protein PGK1_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:P00558] xref: UniProtKB:P00558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040243 ! PGK1_HUMAN [Term] id: CCO:B0040646 name: PGK1_HUMAN-Phosphothreonine243 def: "Protein PGK1_HUMAN with the residue 243 substituted with Phosphothreonine" [UniProtKB:P00558] xref: UniProtKB:P00558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000997 ! phosphoglycerate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0040243 ! PGK1_HUMAN [Term] id: CCO:B0040647 name: PGK1_HUMAN-Phosphoserine390 def: "Protein PGK1_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:P00558] comment: By similarity xref: UniProtKB:P00558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040243 ! PGK1_HUMAN [Term] id: CCO:B0040650 name: PUR2_HUMAN-Phosphotyrosine348 def: "Protein PUR2_HUMAN with the residue 348 substituted with Phosphotyrosine" [UniProtKB:P22102] xref: UniProtKB:P22102 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001011 ! phosphoribosylamine-glycine ligase activity relationship: has_function CCO:F0001015 ! phosphoribosylformylglycinamidine cyclo-ligase activity relationship: has_function CCO:F0001018 ! phosphoribosylglycinamide formyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0021425 ! PUR2_HUMAN [Term] id: CCO:B0040651 name: RS14_HUMAN-Phosphothreonine140 def: "Protein RS14_HUMAN with the residue 140 substituted with Phosphothreonine" [UniProtKB:P62263] xref: UniProtKB:P62263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:B0040654 name: SYT1_HUMAN-Phosphothreonine129 def: "Protein SYT1_HUMAN with the residue 129 substituted with Phosphothreonine" [UniProtKB:P21579] comment: By similarity xref: UniProtKB:P21579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040103 ! SYT1_HUMAN [Term] id: CCO:B0040655 name: SYT1_HUMAN-Phosphotyrosine230 def: "Protein SYT1_HUMAN with the residue 230 substituted with Phosphotyrosine" [UniProtKB:P21579] comment: By similarity xref: UniProtKB:P21579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_function CCO:F0003547 ! syntaxin-1 binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000985 ! secretory granule relationship: located_in CCO:C0001030 ! endocytic vesicle membrane relationship: located_in CCO:C0001036 ! synaptic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0040103 ! SYT1_HUMAN [Term] id: CCO:B0040656 name: SYT1_HUMAN-Phosphotyrosine365 def: "Protein SYT1_HUMAN with the residue 365 substituted with Phosphotyrosine" [UniProtKB:P21579] comment: By similarity xref: UniProtKB:P21579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040103 ! SYT1_HUMAN [Term] id: CCO:B0040657 name: SYT1_HUMAN-Phosphotyrosine381 def: "Protein SYT1_HUMAN with the residue 381 substituted with Phosphotyrosine" [UniProtKB:P21579] comment: By similarity xref: UniProtKB:P21579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040103 ! SYT1_HUMAN [Term] id: CCO:B0040658 name: SYT5_HUMAN-Phosphotyrosine278 def: "Protein SYT5_HUMAN with the residue 278 substituted with Phosphotyrosine" [UniProtKB:O00445] comment: By similarity xref: UniProtKB:O00445 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040093 ! SYT5_HUMAN [Term] id: CCO:B0040661 name: TERA_HUMAN-Phosphoserine702 def: "Protein TERA_HUMAN with the residue 702 substituted with Phosphoserine" [UniProtKB:P55072] xref: UniProtKB:P55072 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:B0040662 name: TERA_HUMAN-Phosphoserine705 def: "Protein TERA_HUMAN with the residue 705 substituted with Phosphoserine" [UniProtKB:P55072] xref: UniProtKB:P55072 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:B0040663 name: UBP8_HUMAN-Phosphoserine434 def: "Protein UBP8_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:P40818] xref: UniProtKB:P40818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040082 ! UBP8_HUMAN [Term] id: CCO:B0040683 name: GABP1_HUMAN def: "GA-binding protein subunit beta-1" [UniProtKB:Q06547] synonym: "GABP subunit beta-1" EXACT [UniProtKB:Q06547] synonym: "GABP subunit beta-2" EXACT [UniProtKB:Q06547] synonym: "GABPB-1" EXACT [UniProtKB:Q06547] synonym: "GABPB-2" EXACT [UniProtKB:Q06547] synonym: "Nuclear respiratory factor 2" EXACT [UniProtKB:Q06547] synonym: "Transcription factor E4TF1-47" EXACT [UniProtKB:Q06547] synonym: "Transcription factor E4TF1-53" EXACT [UniProtKB:Q06547] xref: EMBL:AAA65707.1 xref: EMBL:AAA65708.1 xref: EMBL:AAA65709.1 xref: EMBL:AAA65710.1 xref: EMBL:AAH16910.1 xref: EMBL:AAH36080.1 xref: EMBL:AAH50702.1 xref: EMBL:AAP35298.1 xref: EMBL:BAA02573.1 xref: EMBL:BAA02574.1 xref: UniProtKB:Q06545 xref: UniProtKB:Q06547 xref: UniProtKB:Q12940 xref: UniProtKB:Q12941 xref: UniProtKB:Q12942 xref: UniProtKB:Q8IYD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013375 ! GABPB1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005768 ! fancg-gabpb2 physical interaction relationship: participates_in CCO:I0006868 ! hcfc1-gabp2b1-2 physical interaction relationship: participates_in CCO:I0007261 ! hcfc1-gabp2-3 physical interaction relationship: participates_in CCO:I0007263 ! hcfc1-gabp2-4 direct interaction relationship: participates_in CCO:I0015304 ! gabpb2-lmo3 physical interaction relationship: participates_in CCO:I0015579 ! gabpb2-mageb18 physical interaction relationship: participates_in CCO:I0015685 ! gabpb2-tdrd7 physical interaction relationship: participates_in CCO:I0017618 ! cic-gabpb2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0040684 name: REBL1_HUMAN def: "GTPase RhebL1 precursor" [UniProtKB:Q8TAI7] synonym: "Ras homolog enriched in brain like-1 c" EXACT [UniProtKB:Q8TAI7] synonym: "Ras homolog enriched in brain-like protein 1" EXACT [UniProtKB:Q8TAI7] synonym: "Rheb-like protein 1" EXACT [UniProtKB:Q8TAI7] synonym: "Rheb2" EXACT [UniProtKB:Q8TAI7] synonym: "RhebL1c" EXACT [UniProtKB:Q8TAI7] xref: EMBL:AAH27482.1 xref: EMBL:AAP92804.1 xref: EMBL:AAS80166.1 xref: EMBL:BAC05370.1 xref: EMBL:EAW58038.1 xref: UniProtKB:Q56VH8 xref: UniProtKB:Q8TAI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006028 ! RHEBL1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0005791 ! rhebl1-txnl4a physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0041177 ! REBL1_HUMAN-Cysteine methyl ester180 [Term] id: CCO:B0040685 name: ANR24_HUMAN def: "Ankyrin repeat domain-containing protein 24" [UniProtKB:Q8TF21] xref: EMBL:AAC33490.1 xref: EMBL:AAD15479.1 xref: EMBL:BAB85567.1 xref: UniProtKB:O75268 xref: UniProtKB:O95781 xref: UniProtKB:Q8TF21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006032 ! ANKRD24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008064 ! ankrd24-rif1 physical interaction [Term] id: CCO:B0040686 name: NC2A_HUMAN def: "Dr1-associated corepressor" [UniProtKB:Q14919] synonym: "Dr1-associated protein 1" EXACT [UniProtKB:Q14919] synonym: "NC2-alpha" EXACT [UniProtKB:Q14919] synonym: "Negative co-factor 2-alpha" EXACT [UniProtKB:Q14919] xref: EMBL:AAB02192.1 xref: EMBL:AAH10025.1 xref: EMBL:CAA65358.1 xref: UniProtKB:Q13448 xref: UniProtKB:Q14919 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004511 ! DRAP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008083 ! cdkn2c-drap1 physical interaction relationship: participates_in CCO:I0015019 ! drap1-nfyb physical interaction relationship: participates_in CCO:I0015149 ! drap1-pole3 physical interaction relationship: participates_in CCO:I0015463 ! drap1-pik3r3 physical interaction relationship: participates_in CCO:I0015575 ! drap1-taf9 physical interaction relationship: participates_in CCO:I0015749 ! drap1-taf9l physical interaction relationship: participates_in CCO:I0017623 ! taf9-drap1 physical interaction relationship: participates_in CCO:I0019859 ! tk1-drap1 physical interaction relationship: participates_in CCO:I0020555 ! kiaa1626-drap1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0040687 name: CUX1_HUMAN def: "Homeobox protein cut-like 1" [UniProtKB:P39880] synonym: "CCAAT displacement protein" EXACT [UniProtKB:P39880] synonym: "CDP" EXACT [UniProtKB:P39880] xref: EMBL:AAC78778.1 xref: EMBL:AAH66592.1 xref: UniProtKB:P39880 xref: UniProtKB:Q6NYH4 xref: UniProtKB:Q9UEV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013373 ! CUX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008379 ! cutl1-bin1 physical interaction relationship: participates_in CCO:I0020279 ! cutl1-elac2 physical interaction relationship: participates_in CCO:I0020280 ! cutl1-recql5 physical interaction relationship: participates_in CCO:I0020534 ! cutl1-ca12 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0041130 ! CUX1_HUMAN-Phosphoserine322 relationship: transforms_into CCO:B0041131 ! CUX1_HUMAN-Phosphoserine1218 relationship: transforms_into CCO:B0041132 ! CUX1_HUMAN-Phosphotyrosine1232 relationship: transforms_into CCO:B0041133 ! CUX1_HUMAN-Phosphoserine1233 relationship: transforms_into CCO:B0041134 ! CUX1_HUMAN-Phosphoserine1312 relationship: transforms_into CCO:B0064596 ! CUX1_HUMAN-Phosphoserine1496 [Term] id: CCO:B0040688 name: RPN1_HUMAN def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor" [UniProtKB:P04843] synonym: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit" EXACT [UniProtKB:P04843] synonym: "EC 2.4.1.119" EXACT [UniProtKB:P04843] synonym: "Ribophorin I" EXACT [UniProtKB:P04843] synonym: "Ribophorin-1" EXACT [UniProtKB:P04843] synonym: "RPN-I" EXACT [UniProtKB:P04843] xref: EMBL:AAH10839.1 xref: EMBL:CAA68392.1 xref: EMBL:CAH18139.1 xref: UniProtKB:P04843 xref: UniProtKB:Q68DT1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005487 ! RPN1_human relationship: has_function CCO:F0000962 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000535 ! oligosaccharyl transferase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001057 ! rough endoplasmic reticulum membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0008502 ! rpn1-rbbp4 physical interaction relationship: participates_in CCO:I0016524 ! ikbkg-rpn1 physical interaction relationship: participates_in CCO:I0020655 ! rpn1-dpf1 physical interaction relationship: participates_in CCO:I0020656 ! rpn1-sigirr physical interaction relationship: participates_in CCO:I0020657 ! rpn1-wsb2 physical interaction [Term] id: CCO:B0041106 name: 1433T_HUMAN-N-acetylmethionine1 def: "Protein 1433T_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P27348] xref: UniProtKB:P27348 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001559 ! 1433T_HUMAN [Term] id: CCO:B0041107 name: 4ET_HUMAN-Phosphoserine914 def: "Protein 4ET_HUMAN with the residue 914 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0041108 name: 4ET_HUMAN-Phosphoserine920 def: "Protein 4ET_HUMAN with the residue 920 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0041109 name: ACTB_HUMAN-Phosphothreonine318 def: "Protein ACTB_HUMAN with the residue 318 substituted with Phosphothreonine" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0041110 name: ANM5_HUMAN-N-acetylalanine2 def: "Protein ANM5_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O14744] xref: UniProtKB:O14744 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001357 ! ANM5_HUMAN [Term] id: CCO:B0041111 name: APC1_HUMAN-Phosphoserine202 def: "Protein APC1_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041112 name: APC1_HUMAN-Phosphoserine286 def: "Protein APC1_HUMAN with the residue 286 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041113 name: APC1_HUMAN-Phosphothreonine291 def: "Protein APC1_HUMAN with the residue 291 substituted with Phosphothreonine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041114 name: APC1_HUMAN-Phosphoserine355 def: "Protein APC1_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041115 name: APC1_HUMAN-Phosphoserine373 def: "Protein APC1_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041116 name: APC1_HUMAN-Phosphoserine377 def: "Protein APC1_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041117 name: APC1_HUMAN-Phosphothreonine537 def: "Protein APC1_HUMAN with the residue 537 substituted with Phosphothreonine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041118 name: APC1_HUMAN-Phosphotyrosine571 def: "Protein APC1_HUMAN with the residue 571 substituted with Phosphotyrosine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041119 name: APC1_HUMAN-Phosphoserine686 def: "Protein APC1_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041120 name: APC1_HUMAN-Phosphoserine688 def: "Protein APC1_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041121 name: APC1_HUMAN-Phosphoserine731 def: "Protein APC1_HUMAN with the residue 731 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0041122 name: APC4_HUMAN-Phosphotyrosine469 def: "Protein APC4_HUMAN with the residue 469 substituted with Phosphotyrosine" [UniProtKB:Q9UJX5] xref: UniProtKB:Q9UJX5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002215 ! APC4_HUMAN [Term] id: CCO:B0041123 name: APC4_HUMAN-Phosphoserine779 def: "Protein APC4_HUMAN with the residue 779 substituted with Phosphoserine" [UniProtKB:Q9UJX5] xref: UniProtKB:Q9UJX5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002215 ! APC4_HUMAN [Term] id: CCO:B0041124 name: APC5_HUMAN-Phosphoserine195 def: "Protein APC5_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:Q9UJX4] xref: UniProtKB:Q9UJX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002214 ! APC5_HUMAN [Term] id: CCO:B0041125 name: APC5_HUMAN-Phosphoserine217 def: "Protein APC5_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:Q9UJX4] xref: UniProtKB:Q9UJX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0002214 ! APC5_HUMAN [Term] id: CCO:B0041126 name: BCL3_HUMAN-Phosphoserine394 def: "Protein BCL3_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:P20749] comment: by GSK3; xref: UniProtKB:P20749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001496 ! Bcl3-Bcl10 complex relationship: located_in CCO:C0001560 ! Bcl3/NF-kappaB2 complex relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0005513 ! BCL3_HUMAN [Term] id: CCO:B0041127 name: BCL3_HUMAN-Phosphoserine398 def: "Protein BCL3_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:P20749] comment: by GSK3; xref: UniProtKB:P20749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005513 ! BCL3_HUMAN [Term] id: CCO:B0041128 name: CD2AP_HUMAN-Phosphoserine458 def: "Protein CD2AP_HUMAN with the residue 458 substituted with Phosphoserine" [UniProtKB:Q9Y5K6] xref: UniProtKB:Q9Y5K6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002257 ! CD2AP_HUMAN [Term] id: CCO:B0041129 name: CND3_HUMAN-Phosphothreonine686 def: "Protein CND3_HUMAN with the residue 686 substituted with Phosphothreonine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0041130 name: CUX1_HUMAN-Phosphoserine322 def: "Protein CUX1_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:P39880] xref: UniProtKB:P39880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:B0041131 name: CUX1_HUMAN-Phosphoserine1218 def: "Protein CUX1_HUMAN with the residue 1218 substituted with Phosphoserine" [UniProtKB:P39880] xref: UniProtKB:P39880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:B0041132 name: CUX1_HUMAN-Phosphotyrosine1232 def: "Protein CUX1_HUMAN with the residue 1232 substituted with Phosphotyrosine" [UniProtKB:P39880] xref: UniProtKB:P39880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:B0041133 name: CUX1_HUMAN-Phosphoserine1233 def: "Protein CUX1_HUMAN with the residue 1233 substituted with Phosphoserine" [UniProtKB:P39880] xref: UniProtKB:P39880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:B0041134 name: CUX1_HUMAN-Phosphoserine1312 def: "Protein CUX1_HUMAN with the residue 1312 substituted with Phosphoserine" [UniProtKB:P39880] xref: UniProtKB:P39880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:B0041135 name: EP15_HUMAN-Phosphothreonine777 def: "Protein EP15_HUMAN with the residue 777 substituted with Phosphothreonine" [UniProtKB:P42566] xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0041136 name: EP15_HUMAN-Phosphoserine796 def: "Protein EP15_HUMAN with the residue 796 substituted with Phosphoserine" [UniProtKB:P42566] xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0041137 name: GA2L1_HUMAN-Phosphoserine306 def: "Protein GA2L1_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0041138 name: GA2L1_HUMAN-Phosphoserine352 def: "Protein GA2L1_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0041139 name: H4_HUMAN-Phosphoserine2 def: "Protein H4_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P62805] xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0041140 name: H4_HUMAN-Citrulline4 def: "Protein H4_HUMAN with the residue 4 substituted with Citrulline" [UniProtKB:P62805] comment: alternate; xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0041141 name: H4_HUMAN-Omega-N-methylarginine4 def: "Protein H4_HUMAN with the residue 4 substituted with Omega-N-methylarginine" [UniProtKB:P62805] comment: by PRMT1; alternate; xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0041142 name: H4_HUMAN-N6,N6,N6-trimethyllysine21 def: "Protein H4_HUMAN with the residue 21 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P62805] comment: alternate; xref: UniProtKB:P62805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005700 ! H4_HUMAN [Term] id: CCO:B0041143 name: HD_HUMAN-Phosphoserine434 def: "Protein HD_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:P42858] xref: UniProtKB:P42858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005407 ! HD_HUMAN [Term] id: CCO:B0041144 name: HNRPC_HUMAN-N-acetylalanine2 def: "Protein HNRPC_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0041145 name: IKBA_HUMAN-Phosphoserine283 def: "Protein IKBA_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:P25963] comment: by CK2; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001742 ! nuclear localization sequence binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0041146 name: IKBA_HUMAN-Phosphoserine288 def: "Protein IKBA_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:P25963] comment: by CK2; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0041147 name: IKBA_HUMAN-Phosphothreonine291 def: "Protein IKBA_HUMAN with the residue 291 substituted with Phosphothreonine" [UniProtKB:P25963] comment: by CK2; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0041148 name: IKBA_HUMAN-Phosphoserine293 def: "Protein IKBA_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:P25963] comment: by CK2; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0041149 name: IKBA_HUMAN-Phosphothreonine299 def: "Protein IKBA_HUMAN with the residue 299 substituted with Phosphothreonine" [UniProtKB:P25963] comment: by CK2; xref: UniProtKB:P25963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:B0041150 name: IKBB_HUMAN-Phosphoserine313 def: "Protein IKBB_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q15653] comment: by CK2; xref: UniProtKB:Q15653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:B0041151 name: IKBB_HUMAN-Phosphoserine315 def: "Protein IKBB_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q15653] comment: by CK2; xref: UniProtKB:Q15653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:B0041152 name: IKKB_HUMAN-S-nitrosocysteine179 def: "Protein IKKB_HUMAN with the residue 179 substituted with S-nitrosocysteine" [UniProtKB:O14920] xref: UniProtKB:O14920 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:B0041154 name: KHDR1_HUMAN-Phosphoserine113 def: "Protein KHDR1_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q07666] comment: By similarity xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0041155 name: KI13B_HUMAN-Phosphoserine1644 def: "Protein KI13B_HUMAN with the residue 1644 substituted with Phosphoserine" [UniProtKB:Q9NQT8] xref: UniProtKB:Q9NQT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0005849 ! KI13B_HUMAN [Term] id: CCO:B0041156 name: LIS1_HUMAN-Phosphotyrosine225 def: "Protein LIS1_HUMAN with the residue 225 substituted with Phosphotyrosine" [UniProtKB:P43034] xref: UniProtKB:P43034 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001618 ! LIS1_HUMAN [Term] id: CCO:B0041157 name: M3K5_HUMAN-Phosphoserine1029 def: "Protein M3K5_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q99683] xref: UniProtKB:Q99683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:B0041159 name: MD2L1_HUMAN-N-acetylalanine2 def: "Protein MD2L1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q13257] xref: UniProtKB:Q13257 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001748 ! MD2L1_HUMAN [Term] id: CCO:B0041160 name: MK13_HUMAN-Phosphoserine47 def: "Protein MK13_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:O15264] xref: UniProtKB:O15264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001369 ! MK13_HUMAN [Term] id: CCO:B0041161 name: MTSS1_HUMAN-Phosphoserine261 def: "Protein MTSS1_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:O43312] xref: UniProtKB:O43312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001390 ! MTSS1_HUMAN [Term] id: CCO:B0041162 name: MYH9_HUMAN-Phosphoserine1714 def: "Protein MYH9_HUMAN with the residue 1714 substituted with Phosphoserine" [UniProtKB:P35579] xref: UniProtKB:P35579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:B0041163 name: NEMO_HUMAN-Phosphoserine31 def: "Protein NEMO_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q9Y6K9] comment: by IKKB; xref: UniProtKB:Q9Y6K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:B0041164 name: NEMO_HUMAN-Phosphoserine43 def: "Protein NEMO_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q9Y6K9] comment: by IKKB; xref: UniProtKB:Q9Y6K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000547 ! IkappaB kinase complex relationship: located_in CCO:C0001863 ! cytoplasmic part relationship: transformation_of CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:B0041165 name: NEMO_HUMAN-Phosphoserine68 def: "Protein NEMO_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:Q9Y6K9] xref: UniProtKB:Q9Y6K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:B0041166 name: NEMO_HUMAN-Phosphoserine85 def: "Protein NEMO_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q9Y6K9] comment: by ATM; xref: UniProtKB:Q9Y6K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:B0041167 name: NEMO_HUMAN-Phosphoserine376 def: "Protein NEMO_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q9Y6K9] comment: by IKKB; xref: UniProtKB:Q9Y6K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:B0041168 name: OGT1_HUMAN-N-acetylalanine2 def: "Protein OGT1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O15294] xref: UniProtKB:O15294 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001851 ! acetylglucosaminyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005806 ! OGT1_HUMAN [Term] id: CCO:B0041169 name: P53_HUMAN-Phosphoserine9 def: "Protein P53_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P04637] comment: by HIPK4; xref: UniProtKB:P04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000099 ! DNA strand annealing activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0001483 ! P53_HUMAN [Term] id: CCO:B0041170 name: PARD3_HUMAN-Phosphoserine852 def: "Protein PARD3_HUMAN with the residue 852 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0041171 name: PCAF_HUMAN-Phosphoserine40 def: "Protein PCAF_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q92831] comment: By similarity xref: UniProtKB:Q92831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002019 ! PCAF_HUMAN [Term] id: CCO:B0041172 name: PP1A_HUMAN-Phosphothreonine320 def: "Protein PP1A_HUMAN with the residue 320 substituted with Phosphothreonine" [UniProtKB:P62136] xref: UniProtKB:P62136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001688 ! PP1A_HUMAN [Term] id: CCO:B0041173 name: RASH_HUMAN-N-acetylmethionine1 def: "Protein RASH_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P01112] comment: alternate; xref: UniProtKB:P01112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0001467 ! RASH_HUMAN [Term] id: CCO:B0041174 name: RASH_HUMAN-N-acetylthreonine2 def: "Protein RASH_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P01112] xref: UniProtKB:P01112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001467 ! RASH_HUMAN [Term] id: CCO:B0041175 name: RASK_HUMAN-N-acetylmethionine1 def: "Protein RASK_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P01116] comment: alternate; xref: UniProtKB:P01116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001468 ! RASK_HUMAN [Term] id: CCO:B0041176 name: RASK_HUMAN-N-acetylthreonine2 def: "Protein RASK_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P01116] xref: UniProtKB:P01116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001468 ! RASK_HUMAN [Term] id: CCO:B0041177 name: REBL1_HUMAN-Cysteine methyl ester180 def: "Protein REBL1_HUMAN with the residue 180 substituted with Cysteine methyl ester" [UniProtKB:Q8TAI7] comment: By similarity xref: UniProtKB:Q8TAI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040684 ! REBL1_HUMAN [Term] id: CCO:B0041178 name: RELB_HUMAN-Phosphothreonine103 def: "Protein RELB_HUMAN with the residue 103 substituted with Phosphothreonine" [UniProtKB:Q01201] comment: By similarity xref: UniProtKB:Q01201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:B0041179 name: RELB_HUMAN-Phosphoserine573 def: "Protein RELB_HUMAN with the residue 573 substituted with Phosphoserine" [UniProtKB:Q01201] xref: UniProtKB:Q01201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:B0041180 name: S10A9_HUMAN-Blocked amino end (Thr)2 def: "Protein S10A9_HUMAN with the residue 2 substituted with Blocked amino end (Thr)" [UniProtKB:P06702] xref: UniProtKB:P06702 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005461 ! S10A9_HUMAN [Term] id: CCO:B0041181 name: SCG1_HUMAN-Phosphothreonine79 def: "Protein SCG1_HUMAN with the residue 79 substituted with Phosphothreonine" [UniProtKB:P05060] comment: Probable xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041182 name: SCG1_HUMAN-Phosphoserine99 def: "Protein SCG1_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041183 name: SCG1_HUMAN-Phosphoserine100 def: "Protein SCG1_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041184 name: SCG1_HUMAN-Phosphoserine293 def: "Protein SCG1_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041185 name: SCG1_HUMAN-Phosphoserine294 def: "Protein SCG1_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041186 name: SCG1_HUMAN-Phosphoserine380 def: "Protein SCG1_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:P05060] xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041187 name: SCG1_HUMAN-Sulfotyrosine471 def: "Protein SCG1_HUMAN with the residue 471 substituted with Sulfotyrosine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041188 name: SCG1_HUMAN-Sulfotyrosine474 def: "Protein SCG1_HUMAN with the residue 474 substituted with Sulfotyrosine" [UniProtKB:P05060] comment: Probable xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041189 name: SCG1_HUMAN-Phosphoserine533 def: "Protein SCG1_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041190 name: SCG1_HUMAN-Phosphoserine534 def: "Protein SCG1_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041191 name: SCG1_HUMAN-Sulfotyrosine566 def: "Protein SCG1_HUMAN with the residue 566 substituted with Sulfotyrosine" [UniProtKB:P05060] comment: Probable xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041192 name: SCG1_HUMAN-Sulfotyrosine568 def: "Protein SCG1_HUMAN with the residue 568 substituted with Sulfotyrosine" [UniProtKB:P05060] comment: Potential xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041193 name: SCG1_HUMAN-Phosphoserine631 def: "Protein SCG1_HUMAN with the residue 631 substituted with Phosphoserine" [UniProtKB:P05060] comment: By similarity xref: UniProtKB:P05060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:B0041194 name: SEPT5_HUMAN-Phosphoserine225 def: "Protein SEPT5_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q99719] xref: UniProtKB:Q99719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002085 ! SEPT5_HUMAN [Term] id: CCO:B0041195 name: SIRT2_HUMAN-Phosphoserine25 def: "Protein SIRT2_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q8IXJ6] xref: UniProtKB:Q8IXJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0005559 ! histone acetyltransferase binding relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_function CCO:F0005738 ! tubulin deacetylase activity relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0001951 ! SIRT2_HUMAN [Term] id: CCO:B0041196 name: SIRT2_HUMAN-Phosphoserine27 def: "Protein SIRT2_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q8IXJ6] xref: UniProtKB:Q8IXJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001951 ! SIRT2_HUMAN [Term] id: CCO:B0041197 name: SPTB2_HUMAN-Phosphoserine2164 def: "Protein SPTB2_HUMAN with the residue 2164 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0041198 name: SRC_HUMAN-Phosphothreonine74 def: "Protein SRC_HUMAN with the residue 74 substituted with Phosphothreonine" [UniProtKB:P12931] xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0041199 name: STK6_HUMAN-Phosphothreonine287 def: "Protein STK6_HUMAN with the residue 287 substituted with Phosphothreonine" [UniProtKB:O14965] xref: UniProtKB:O14965 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: transformation_of CCO:B0001363 ! STK6_HUMAN [Term] id: CCO:B0041200 name: STK6_HUMAN-Phosphothreonine288 def: "Protein STK6_HUMAN with the residue 288 substituted with Phosphothreonine" [UniProtKB:O14965] xref: UniProtKB:O14965 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001363 ! STK6_HUMAN [Term] id: CCO:B0041201 name: T22D4_HUMAN-Phosphoserine62 def: "Protein T22D4_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0041202 name: T22D4_HUMAN-Phosphoserine165 def: "Protein T22D4_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0041203 name: T22D4_HUMAN-Phosphothreonine211 def: "Protein T22D4_HUMAN with the residue 211 substituted with Phosphothreonine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0041204 name: T22D4_HUMAN-Phosphoserine279 def: "Protein T22D4_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0041205 name: TBA4A_HUMAN-Phosphoserine439 def: "Protein TBA4A_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:P68366] xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0041206 name: TBA4A_HUMAN-Phosphotyrosine440 def: "Protein TBA4A_HUMAN with the residue 440 substituted with Phosphotyrosine" [UniProtKB:P68366] xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0041207 name: TF65_HUMAN-N6-acetyllysine122 def: "Protein TF65_HUMAN with the residue 122 substituted with N6-acetyllysine" [UniProtKB:Q04206] comment: by PCAF and EP300; xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005656 ! phosphate binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041208 name: TF65_HUMAN-N6-acetyllysine123 def: "Protein TF65_HUMAN with the residue 123 substituted with N6-acetyllysine" [UniProtKB:Q04206] comment: by PCAF and EP300; xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041209 name: TF65_HUMAN-Phosphothreonine254 def: "Protein TF65_HUMAN with the residue 254 substituted with Phosphothreonine" [UniProtKB:Q04206] xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041210 name: TF65_HUMAN-Phosphoserine281 def: "Protein TF65_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q04206] comment: Probable xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041211 name: TF65_HUMAN-N6-acetyllysine310 def: "Protein TF65_HUMAN with the residue 310 substituted with N6-acetyllysine" [UniProtKB:Q04206] xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041212 name: TF65_HUMAN-Phosphoserine311 def: "Protein TF65_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q04206] comment: by PKC/PRKCZ; By similarity xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041213 name: TF65_HUMAN-Phosphothreonine435 def: "Protein TF65_HUMAN with the residue 435 substituted with Phosphothreonine" [UniProtKB:Q04206] xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041214 name: TF65_HUMAN-Phosphoserine468 def: "Protein TF65_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:Q04206] comment: by IKKB and IKKE; xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041215 name: TF65_HUMAN-Phosphothreonine505 def: "Protein TF65_HUMAN with the residue 505 substituted with Phosphothreonine" [UniProtKB:Q04206] comment: by CHK1; xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041216 name: TF65_HUMAN-Phosphoserine529 def: "Protein TF65_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:Q04206] comment: by CK2; xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041217 name: TF65_HUMAN-Phosphoserine536 def: "Protein TF65_HUMAN with the residue 536 substituted with Phosphoserine" [UniProtKB:Q04206] comment: by IKKB; xref: UniProtKB:Q04206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:B0041218 name: TNIK_HUMAN-Phosphothreonine581 def: "Protein TNIK_HUMAN with the residue 581 substituted with Phosphothreonine" [UniProtKB:Q9UKE5] xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0041219 name: TNIK_HUMAN-Phosphoserine640 def: "Protein TNIK_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q9UKE5] xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0041220 name: TNIK_HUMAN-Phosphothreonine677 def: "Protein TNIK_HUMAN with the residue 677 substituted with Phosphothreonine" [UniProtKB:Q9UKE5] xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0041221 name: TXD11_HUMAN-Phosphoserine828 def: "Protein TXD11_HUMAN with the residue 828 substituted with Phosphoserine" [UniProtKB:Q6PKC3] xref: UniProtKB:Q6PKC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005993 ! TXD11_HUMAN [Term] id: CCO:B0041222 name: ZN363_HUMAN-Phosphoserine257 def: "Protein ZN363_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:Q96PM5] xref: UniProtKB:Q96PM5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005980 ! ZN363_HUMAN [Term] id: CCO:B0041223 name: ZYX_HUMAN-N-acetylalanine2 def: "Protein ZYX_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0041227 name: B1AHR1_HUMAN def: "Septin" [UniProtKB:B1AHR1] xref: EMBL:CAQ07553.1 xref: UniProtKB:B1AHR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005586 ! SEPT3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0041228 name: B1AK43_HUMAN def: "MAD2 mitotic arrest deficient-like 2 (Yeast)" [UniProtKB:B1AK43] xref: EMBL:CAI20216.1 xref: UniProtKB:B1AK43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005049 ! MAD2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0041229 name: B1AK44_HUMAN def: "MAD2 mitotic arrest deficient-like 2 (Yeast)" [UniProtKB:B1AK44] xref: EMBL:CAI20217.1 xref: UniProtKB:B1AK44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005049 ! MAD2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0041230 name: B1AK45_HUMAN def: "MAD2 mitotic arrest deficient-like 2 (Yeast)" [UniProtKB:B1AK45] xref: EMBL:CAI20219.1 xref: UniProtKB:B1AK45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005049 ! MAD2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0041231 name: B1AK46_HUMAN def: "MAD2 mitotic arrest deficient-like 2 (Yeast)" [UniProtKB:B1AK46] xref: EMBL:CAI20220.1 xref: UniProtKB:B1AK46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005049 ! MAD2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0041232 name: B1AK47_HUMAN def: "MAD2 mitotic arrest deficient-like 2 (Yeast)" [UniProtKB:B1AK47] xref: EMBL:CAI20221.1 xref: UniProtKB:B1AK47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005049 ! MAD2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0041233 name: B1ALC7_HUMAN def: "Microtubule-actin crosslinking factor 1" [UniProtKB:B1ALC7] xref: EMBL:CAI21818.1 xref: UniProtKB:B1ALC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005012 ! MACF1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0041234 name: B1AMS2_HUMAN def: "Septin" [UniProtKB:B1AMS2] xref: EMBL:CAI41427.1 xref: EMBL:EAW89852.1 xref: UniProtKB:B1AMS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005589 ! SEPT6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001135 ! septin complex relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0041235 name: B1ANQ7_HUMAN def: "Microtubule-actin crosslinking factor 1" [UniProtKB:B1ANQ7] xref: EMBL:CAI16411.1 xref: UniProtKB:B1ANQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005012 ! MACF1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0041236 name: B1ANR2_HUMAN def: "Microtubule-actin crosslinking factor 1" [UniProtKB:B1ANR2] xref: EMBL:CAI16416.1 xref: UniProtKB:B1ANR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005012 ! MACF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0041237 name: B1AQT3_HUMAN def: "NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)" [UniProtKB:B1AQT3] xref: EMBL:CAI16704.1 xref: UniProtKB:B1AQT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005224 ! NUF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0041238 name: B1AQT4_HUMAN def: "NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)" [UniProtKB:B1AQT4] xref: EMBL:CAI16705.1 xref: UniProtKB:B1AQT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005224 ! NUF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0000081 ! mitosis [Term] id: CCO:B0041239 name: PSMD9_HUMAN def: "26S proteasome non-ATPase regulatory subunit 9" [UniProtKB:O00233] synonym: "26S proteasome regulatory subunit p27" EXACT [UniProtKB:O00233] xref: EMBL:AAH02383.1 xref: EMBL:AAH04184.1 xref: EMBL:AAH04213.1 xref: EMBL:BAA19790.1 xref: UniProtKB:O00233 xref: UniProtKB:Q9BQ42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013405 ! PSMD9_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005853 ! bHLH transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002079 ! proteasome regulatory particle relationship: participates_in CCO:I0008691 ! psmc6-psmd9 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0001532 ! positive regulation of insulin secretion relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002733 ! negative regulation of insulin secretion relationship: transforms_into CCO:B0041336 ! PSMD9_HUMAN-Phosphoserine129 [Term] id: CCO:B0041240 name: PSD10_HUMAN def: "26S proteasome non-ATPase regulatory subunit 10" [UniProtKB:O75832] synonym: "26S proteasome regulatory subunit p28" EXACT [UniProtKB:O75832] synonym: "Gankyrin" EXACT [UniProtKB:O75832] xref: EMBL:AAH11960.1 xref: EMBL:BAA33215.1 xref: EMBL:BAA34594.1 xref: EMBL:CAA20117.1 xref: UniProtKB:O75832 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013402 ! PSMD10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008699 ! psmc4-psmd10 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041328 ! PSD10_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0041241 name: CCDB1_HUMAN def: "Cyclin-D1-binding protein 1" [UniProtKB:O95273] synonym: "Grap2 and cyclin-D-interacting protein" EXACT [UniProtKB:O95273] synonym: "Human homolog of Maid" EXACT [UniProtKB:O95273] xref: EMBL:AAD11777.1 xref: EMBL:AAF14872.1 xref: EMBL:AAF67182.1 xref: EMBL:AAF77613.1 xref: EMBL:AAH09689.1 xref: EMBL:AAP97163.1 xref: EMBL:BAC11433.1 xref: EMBL:BAC11530.1 xref: EMBL:BAC87645.1 xref: EMBL:BAF83354.1 xref: EMBL:BAF83396.1 xref: EMBL:CAG29327.1 xref: EMBL:EAW92588.1 xref: EMBL:EAW92590.1 xref: UniProtKB:A8K3Q0 xref: UniProtKB:A8K3U2 xref: UniProtKB:O95273 xref: UniProtKB:Q6ZQN9 xref: UniProtKB:Q7Z519 xref: UniProtKB:Q8NBS7 xref: UniProtKB:Q8NBY2 xref: UniProtKB:Q9NS19 xref: UniProtKB:Q9NYH3 xref: UniProtKB:Q9UHX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013383 ! CCNDBP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008821 ! mrps9-ccndbp1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0041242 name: PRS6A_HUMAN def: "26S protease regulatory subunit 6A" [UniProtKB:P17980] synonym: "Proteasome 26S subunit ATPase 3" EXACT [UniProtKB:P17980] synonym: "Proteasome subunit P50" EXACT [UniProtKB:P17980] synonym: "TAT-binding protein 1" EXACT [UniProtKB:P17980] synonym: "TBP-1" EXACT [UniProtKB:P17980] xref: EMBL:AAA36666.1 xref: EMBL:AAH08713.4 xref: EMBL:AAH73165.3 xref: EMBL:AAI06921.1 xref: EMBL:AAI07805.1 xref: EMBL:BAD96205.1 xref: EMBL:CAG33012.1 xref: UniProtKB:P17980 xref: UniProtKB:Q3B757 xref: UniProtKB:Q3B865 xref: UniProtKB:Q53HU5 xref: UniProtKB:Q6GPG8 xref: UniProtKB:Q6IBS1 xref: UniProtKB:Q96HD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013394 ! PSMC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008716 ! traf6-psmc3 physical interaction relationship: participates_in CCO:I0008785 ! atxn1-psmc3 physical interaction relationship: participates_in CCO:I0008811 ! stx11-psmc3 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041314 ! PRS6A_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0041315 ! PRS6A_HUMAN-Phosphoserine9 [Term] id: CCO:B0041243 name: PSA2_HUMAN def: "Proteasome subunit alpha type-2" [UniProtKB:P25787] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P25787] synonym: "Macropain subunit C3" EXACT [UniProtKB:P25787] synonym: "Multicatalytic endopeptidase complex subunit C3" EXACT [UniProtKB:P25787] synonym: "Proteasome component C3" EXACT [UniProtKB:P25787] xref: EMBL:AAH02900.2 xref: EMBL:AAH47697.1 xref: EMBL:BAA00657.1 xref: UniProtKB:P25787 xref: UniProtKB:Q9BU45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013398 ! PSMA2_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008724 ! alpha1-alpha2 physical interaction relationship: participates_in CCO:I0008728 ! alpha2-alpha1 physical interaction relationship: participates_in CCO:I0008729 ! alpha2-alpha4 physical interaction relationship: participates_in CCO:I0008731 ! alpha3-alpha2 physical interaction relationship: participates_in CCO:I0008733 ! alpha4-alpha2 physical interaction relationship: participates_in CCO:I0008735 ! alpha6-alpha2 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041318 ! PSA2_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0041319 ! PSA2_HUMAN-Phosphotyrosine24 relationship: transforms_into CCO:B0041320 ! PSA2_HUMAN-Phosphotyrosine76 relationship: transforms_into CCO:B0041321 ! PSA2_HUMAN-Phosphotyrosine98 relationship: transforms_into CCO:B0041322 ! PSA2_HUMAN-Phosphotyrosine121 relationship: transforms_into CCO:B0041323 ! PSA2_HUMAN-Nitrated tyrosine229 relationship: transforms_into CCO:B0069562 ! PSA2_HUMAN-Phosphotyrosine57 [Term] id: CCO:B0041244 name: PSA4_HUMAN def: "Proteasome subunit alpha type-4" [UniProtKB:P25789] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P25789] synonym: "Macropain subunit C9" EXACT [UniProtKB:P25789] synonym: "Multicatalytic endopeptidase complex subunit C9" EXACT [UniProtKB:P25789] synonym: "Proteasome component C9" EXACT [UniProtKB:P25789] synonym: "Proteasome subunit L" EXACT [UniProtKB:P25789] xref: EMBL:AAH05361.1 xref: EMBL:AAH22445.1 xref: EMBL:AAH22817.2 xref: EMBL:AAH47667.1 xref: EMBL:BAA00660.1 xref: UniProtKB:P25789 xref: UniProtKB:Q8TBD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013399 ! PSMA4_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008706 ! traf6-psma4 physical interaction relationship: participates_in CCO:I0008729 ! alpha2-alpha4 physical interaction relationship: participates_in CCO:I0008730 ! alpha3-alpha4 physical interaction relationship: participates_in CCO:I0008732 ! alpha4-alpha3 physical interaction relationship: participates_in CCO:I0008733 ! alpha4-alpha2 physical interaction relationship: participates_in CCO:I0008734 ! alpha4-alpha7 physical interaction relationship: participates_in CCO:I0008738 ! alpha7-alpha4 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041324 ! PSA4_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0041325 ! PSA4_HUMAN-Phosphoserine75 [Term] id: CCO:B0041245 name: PSB4_HUMAN def: "Proteasome subunit beta type-4 precursor" [UniProtKB:P28070] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P28070] synonym: "HsBPROS26" EXACT [UniProtKB:P28070] synonym: "HSN3" EXACT [UniProtKB:P28070] synonym: "Macropain beta chain" EXACT [UniProtKB:P28070] synonym: "Multicatalytic endopeptidase complex beta chain" EXACT [UniProtKB:P28070] synonym: "Proteasome beta chain" EXACT [UniProtKB:P28070] synonym: "Proteasome chain 3" EXACT [UniProtKB:P28070] xref: EMBL:AAB31085.1 xref: EMBL:AAH00331.1 xref: EMBL:AAH08314.1 xref: EMBL:AAH10088.1 xref: EMBL:AAH10098.1 xref: EMBL:AAH11768.1 xref: EMBL:AAH12168.1 xref: EMBL:AAH17307.1 xref: EMBL:AAH17451.1 xref: EMBL:AAH17486.1 xref: EMBL:AAP35563.1 xref: EMBL:BAA05647.1 xref: EMBL:CAI16806.1 xref: UniProtKB:P28070 xref: UniProtKB:P31148 xref: UniProtKB:Q5SZS5 xref: UniProtKB:Q969L6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013401 ! PSMB4_human relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041327 ! PSB4_HUMAN-Phosphotyrosine102 [Term] id: CCO:B0041246 name: PRS7_HUMAN def: "26S protease regulatory subunit 7" [UniProtKB:P35998] synonym: "Proteasome 26S subunit ATPase 2" EXACT [UniProtKB:P35998] synonym: "Protein MSS1" EXACT [UniProtKB:P35998] xref: EMBL:AAH02589.1 xref: EMBL:BAA01868.1 xref: UniProtKB:P35998 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013396 ! PSMC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008697 ! psmc2-psmd5 physical interaction relationship: participates_in CCO:I0008715 ! traf6-psmc2 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0041247 name: PRS6B_HUMAN def: "26S protease regulatory subunit 6B" [UniProtKB:P43686] synonym: "MB67-interacting protein" EXACT [UniProtKB:P43686] synonym: "MIP224" EXACT [UniProtKB:P43686] synonym: "Proteasome 26S subunit ATPase 4" EXACT [UniProtKB:P43686] synonym: "TAT-binding protein 7" EXACT [UniProtKB:P43686] synonym: "TBP-7" EXACT [UniProtKB:P43686] xref: EMBL:AAC26843.1 xref: EMBL:AAC32612.1 xref: EMBL:AAC99817.1 xref: EMBL:AAD39267.1 xref: EMBL:AAH00343.1 xref: EMBL:AAH10396.1 xref: EMBL:AAH14488.1 xref: EMBL:AAP35896.1 xref: UniProtKB:P43686 xref: UniProtKB:Q96FV5 xref: UniProtKB:Q9UBM3 xref: UniProtKB:Q9UEX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013395 ! PSMC4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008677 ! psmc4-psmc5 physical interaction relationship: participates_in CCO:I0008699 ! psmc4-psmd10 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041316 ! PRS6B_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0069561 ! PRS6B_HUMAN-Phosphoserine28 [Term] id: CCO:B0041248 name: UB2E1_HUMAN def: "Ubiquitin-conjugating enzyme E2 E1" [UniProtKB:P51965] synonym: "EC 6.3.2.19" EXACT [UniProtKB:P51965] synonym: "UbcH6" EXACT [UniProtKB:P51965] synonym: "Ubiquitin carrier protein E1" EXACT [UniProtKB:P51965] synonym: "Ubiquitin-protein ligase E1" EXACT [UniProtKB:P51965] xref: EMBL:AAH09139.1 xref: EMBL:CAA63539.1 xref: UniProtKB:P51965 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013410 ! UBE2E1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_function CCO:F0008371 ! ISG15 ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008771 ! hsrma1-ube2e1 physical interaction relationship: participates_in CCO:I0008812 ! ube2e1-cbwd3 physical interaction relationship: participates_in CCO:I0008813 ! ube2e1-paep physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle [Term] id: CCO:B0041249 name: HMGA2_HUMAN def: "High mobility group protein HMGI-C" [UniProtKB:P52926] synonym: "High mobility group AT-hook protein 2" EXACT [UniProtKB:P52926] xref: EMBL:AAA68613.1 xref: EMBL:AAA68614.1 xref: EMBL:AAA96484.1 xref: EMBL:CAA63295.1 xref: EMBL:CAA83472.1 xref: UniProtKB:P52926 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011851 ! HMGA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000276 ! AT DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0008767 ! hrmt1l2-hmga2 physical interaction relationship: participates_in CCO:I0008768 ! hrmt1l6-hmg2a physical interaction relationship: participates_in CCO:I0008770 ! hrmt1l6-hmga2 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041306 ! HMGA2_HUMAN-Phosphoserine105 [Term] id: CCO:B0041250 name: PSMD4_HUMAN def: "26S proteasome non-ATPase regulatory subunit 4" [UniProtKB:P55036] synonym: "26S proteasome regulatory subunit S5A" EXACT [UniProtKB:P55036] synonym: "AF" EXACT [UniProtKB:P55036] synonym: "Antisecretory factor 1" EXACT [UniProtKB:P55036] synonym: "ASF" EXACT [UniProtKB:P55036] synonym: "Multiubiquitin chain-binding protein" EXACT [UniProtKB:P55036] synonym: "Rpn10" EXACT [UniProtKB:P55036] xref: EMBL:AAB54057.1 xref: EMBL:AAB68598.1 xref: EMBL:AAC50433.1 xref: EMBL:AAH02365.1 xref: EMBL:AAH72008.1 xref: EMBL:BAA97581.1 xref: EMBL:CAH70329.1 xref: EMBL:CAI16390.1 xref: UniProtKB:P55036 xref: UniProtKB:Q5VWC5 xref: UniProtKB:Q9NS92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013403 ! PSMD4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008690 ! c12orf2-psmd4 physical interaction relationship: participates_in CCO:I0008708 ! traf6-psmd4 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041330 ! PSMD4_HUMAN-Phosphothreonine250 relationship: transforms_into CCO:B0041331 ! PSMD4_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0041332 ! PSMD4_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0041333 ! PSMD4_HUMAN-Phosphoserine358 relationship: transforms_into CCO:B0041334 ! PSMD4_HUMAN-Phosphoserine361 [Term] id: CCO:B0041251 name: PSA6_HUMAN def: "Proteasome subunit alpha type-6" [UniProtKB:P60900] synonym: "27 kDa prosomal protein" EXACT [UniProtKB:P60900] synonym: "EC 3.4.25.1" EXACT [UniProtKB:P60900] synonym: "Macropain iota chain" EXACT [UniProtKB:P60900] synonym: "Multicatalytic endopeptidase complex iota chain" EXACT [UniProtKB:P60900] synonym: "p27K" EXACT [UniProtKB:P60900] synonym: "PROS-27" EXACT [UniProtKB:P60900] synonym: "Proteasome iota chain" EXACT [UniProtKB:P60900] xref: EMBL:AAH02979.1 xref: EMBL:AAH17882.1 xref: EMBL:AAH22354.1 xref: EMBL:AAH23659.1 xref: EMBL:AAH70137.1 xref: EMBL:CAA42052.1 xref: EMBL:CAA43964.1 xref: EMBL:CAG33225.1 xref: UniProtKB:P34062 xref: UniProtKB:P60900 xref: UniProtKB:Q6IB60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013400 ! PSMA6_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000721 ! threonine endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: participates_in CCO:I0008735 ! alpha6-alpha2 physical interaction relationship: participates_in CCO:I0008736 ! alpha6-alpha7 physical interaction relationship: participates_in CCO:I0008739 ! alpha7-alpha6 physical interaction relationship: participates_in CCO:I0008773 ! 20s proteasome-1 physical interaction relationship: participates_in CCO:I0008792 ! psma3-psma6-1 physical interaction relationship: participates_in CCO:I0008793 ! 20s proteasome physical interaction relationship: participates_in CCO:I0008795 ! psma6-psma3 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041326 ! PSA6_HUMAN-Phosphotyrosine159 relationship: transforms_into CCO:B0069563 ! PSA6_HUMAN-Phosphotyrosine160 [Term] id: CCO:B0041252 name: PSME3_HUMAN def: "Proteasome activator complex subunit 3" [UniProtKB:P61289] synonym: "11S regulator complex subunit gamma" EXACT [UniProtKB:P61289] synonym: "Activator of multicatalytic protease subunit 3" EXACT [UniProtKB:P61289] synonym: "Ki nuclear autoantigen" EXACT [UniProtKB:P61289] synonym: "PA28g" EXACT [UniProtKB:P61289] synonym: "PA28gamma" EXACT [UniProtKB:P61289] synonym: "Proteasome activator 28 subunit gamma" EXACT [UniProtKB:P61289] synonym: "REG-gamma" EXACT [UniProtKB:P61289] xref: EMBL:AAA93227.1 xref: EMBL:AAB60335.1 xref: EMBL:AAH01423.1 xref: EMBL:AAH02684.1 xref: EMBL:AAH08020.1 xref: EMBL:AAV38193.1 xref: UniProtKB:O35563 xref: UniProtKB:P61289 xref: UniProtKB:P97373 xref: UniProtKB:Q12920 xref: UniProtKB:Q13172 xref: UniProtKB:Q9BQD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013406 ! PSME3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001986 ! proteasome activator activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000548 ! proteasome activator complex relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008679 ! psme3-zcchc10 physical interaction relationship: participates_in CCO:I0008683 ! bbs2-psme3 physical interaction relationship: participates_in CCO:I0008684 ! psme3-serf2 physical interaction relationship: participates_in CCO:I0008688 ! psme3-psme3-1 physical interaction relationship: participates_in CCO:I0008693 ! itpkb-psme3 physical interaction relationship: participates_in CCO:I0008700 ! ncoa3-psme3-2 physical interaction relationship: participates_in CCO:I0008702 ! ncoa3-psme3 physical interaction relationship: participates_in CCO:I0008704 ! nfkbie-psme3 physical interaction relationship: participates_in CCO:I0008760 ! dtnbp1-psme3 physical interaction relationship: participates_in CCO:I0008762 ! psme3-coil physical interaction relationship: participates_in CCO:I0008764 ! atn1-psme3-2 physical interaction relationship: participates_in CCO:I0008765 ! coil-psme3-1 physical interaction relationship: participates_in CCO:I0008769 ! ncoa3-psme3-1 physical interaction relationship: participates_in CCO:I0008781 ! atn1-psme3 physical interaction relationship: participates_in CCO:I0008783 ! atn1-psme3-1 physical interaction relationship: participates_in CCO:I0008786 ! coil-psme3 physical interaction relationship: participates_in CCO:I0008790 ! ncoa3-psme3-3 direct interaction relationship: participates_in CCO:I0008791 ! ncoa3-psme3-4 direct interaction relationship: participates_in CCO:I0008801 ! psme3-hspa5 physical interaction relationship: participates_in CCO:I0008808 ! psme3-atp5b physical interaction relationship: participates_in CCO:I0008809 ! psme3-centa1 physical interaction relationship: participates_in CCO:I0008810 ! psme3-psme3 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041337 ! PSME3_HUMAN-Phosphothreonine205 relationship: transforms_into CCO:B0041338 ! PSME3_HUMAN-Phosphothreonine207 [Term] id: CCO:B0041253 name: PRS8_HUMAN def: "26S protease regulatory subunit 8" [UniProtKB:P62195] synonym: "p45/SUG" EXACT [UniProtKB:P62195] synonym: "Proteasome 26S subunit ATPase 5" EXACT [UniProtKB:P62195] synonym: "Proteasome subunit p45" EXACT [UniProtKB:P62195] synonym: "Thyroid hormone receptor-interacting protein 1" EXACT [UniProtKB:P62195] synonym: "TRIP1" EXACT [UniProtKB:P62195] xref: EMBL:AAB88187.1 xref: EMBL:AAC41735.1 xref: EMBL:AAH01932.1 xref: EMBL:AAH02367.3 xref: EMBL:BAA07919.1 xref: UniProtKB:O35051 xref: UniProtKB:O43208 xref: UniProtKB:P47210 xref: UniProtKB:P52915 xref: UniProtKB:P52916 xref: UniProtKB:P62195 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013397 ! PSMC5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0004681 ! thyrotropin-releasing hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008677 ! psmc4-psmc5 physical interaction relationship: participates_in CCO:I0008685 ! psmc5-rora physical interaction relationship: participates_in CCO:I0008687 ! psmc5-tnnt1 physical interaction relationship: participates_in CCO:I0008696 ! krt15-psmc5 physical interaction relationship: participates_in CCO:I0008709 ! traf6-psmc5 physical interaction relationship: participates_in CCO:I0008763 ! psmc5-rora-1 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0002151 ! negative regulation of programmed cell death relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: transforms_into CCO:B0041317 ! PRS8_HUMAN-N-acetylalanine2 [Term] id: CCO:B0041254 name: PTOR1_HUMAN def: "Protor-1" [UniProtKB:P85299] synonym: "Proline-rich protein 5" EXACT [UniProtKB:P85299] synonym: "Protein observed with Rictor-1" EXACT [UniProtKB:P85299] xref: EMBL:AAG17975.1 xref: EMBL:AAH16921.1 xref: EMBL:BAA90999.1 xref: EMBL:DAA05654.1 xref: EMBL:DAA05655.1 xref: EMBL:DAA05656.1 xref: EMBL:DAA05657.1 xref: EMBL:DAA05658.1 xref: UniProtKB:O75983 xref: UniProtKB:O95695 xref: UniProtKB:P85299 xref: UniProtKB:Q5BIW2 xref: UniProtKB:Q5EAJ8 xref: UniProtKB:Q5EAJ9 xref: UniProtKB:Q5XKJ6 xref: UniProtKB:Q96RW1 xref: UniProtKB:Q96RW2 xref: UniProtKB:Q9HA49 xref: UniProtKB:Q9HC46 xref: UniProtKB:Q9NSG0 xref: UniProtKB:Q9NVX8 xref: UniProtKB:Q9NXL1 xref: UniProtKB:Q9UH20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013408 ! PROTOR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0041255 name: PSMD5_HUMAN def: "26S proteasome non-ATPase regulatory subunit 5" [UniProtKB:Q16401] synonym: "26S protease subunit S5 basic" EXACT [UniProtKB:Q16401] synonym: "26S proteasome subunit S5B" EXACT [UniProtKB:Q16401] xref: EMBL:AAB35397.1 xref: EMBL:AAH14478.1 xref: EMBL:BAA06687.1 xref: EMBL:CAI95118.1 xref: EMBL:EAW87471.1 xref: UniProtKB:Q15045 xref: UniProtKB:Q16401 xref: UniProtKB:Q4VXG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013404 ! PSMD5_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: participates_in CCO:I0008697 ! psmc2-psmd5 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0041335 ! PSMD5_HUMAN-N-acetylalanine2 [Term] id: CCO:B0041256 name: ERC6L_HUMAN def: "DNA excision repair protein ERCC-6-like" [UniProtKB:Q2NKX8] synonym: "ATP-dependent helicase ERCC6-like" EXACT [UniProtKB:Q2NKX8] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q2NKX8] synonym: "PLK1-interacting checkpoint helicase" EXACT [UniProtKB:Q2NKX8] synonym: "Tumor antigen BJ-HCC-15" EXACT [UniProtKB:Q2NKX8] xref: EMBL:AAH08808.1 xref: EMBL:AAI11487.1 xref: EMBL:AAM82750.1 xref: EMBL:ABU25227.1 xref: EMBL:BAA90952.1 xref: EMBL:BAC11160.1 xref: UniProtKB:Q2NKX8 xref: UniProtKB:Q8NCI1 xref: UniProtKB:Q96H93 xref: UniProtKB:Q9NXQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013389 ! ERCC6L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041302 ! ERC6L_HUMAN-Phosphoserine1021 relationship: transforms_into CCO:B0041303 ! ERC6L_HUMAN-Phosphothreonine1063 relationship: transforms_into CCO:B0065105 ! ERC6L_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0065106 ! ERC6L_HUMAN-Phosphoserine774 relationship: transforms_into CCO:B0065107 ! ERC6L_HUMAN-Phosphoserine807 relationship: transforms_into CCO:B0065108 ! ERC6L_HUMAN-Phosphoserine810 relationship: transforms_into CCO:B0065109 ! ERC6L_HUMAN-Phosphothreonine813 relationship: transforms_into CCO:B0065110 ! ERC6L_HUMAN-Phosphoserine820 relationship: transforms_into CCO:B0065111 ! ERC6L_HUMAN-Phosphoserine1028 relationship: transforms_into CCO:B0065112 ! ERC6L_HUMAN-Phosphoserine1069 [Term] id: CCO:B0041257 name: E4F1_HUMAN def: "Transcription factor E4F1" [UniProtKB:Q66K89] synonym: "E4F transcription factor 1" EXACT [UniProtKB:Q66K89] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q66K89] synonym: "p120E4F" EXACT [UniProtKB:Q66K89] synonym: "p50E4F" EXACT [UniProtKB:Q66K89] synonym: "Putative E3 ubiquitin-protein ligase E4F1" EXACT [UniProtKB:Q66K89] synonym: "Transcription factor E4F" EXACT [UniProtKB:Q66K89] xref: EMBL:AAD09139.1 xref: EMBL:AAH80524.1 xref: EMBL:BAF83018.1 xref: EMBL:EAW85532.1 xref: UniProtKB:A8K2R4 xref: UniProtKB:O00146 xref: UniProtKB:Q66K89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013388 ! E4F1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000081 ! mitosis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0041258 name: XAF1_HUMAN def: "XIAP-associated factor 1" [UniProtKB:Q6GPH4] synonym: "BIRC4-binding protein" EXACT [UniProtKB:Q6GPH4] xref: EMBL:AAH32776.1 xref: EMBL:AAH73156.1 xref: EMBL:ABM74556.1 xref: EMBL:ABM74557.1 xref: EMBL:BAF82965.1 xref: EMBL:BAF85399.1 xref: EMBL:BAF85537.1 xref: EMBL:CAA68030.1 xref: EMBL:CAE46206.1 xref: EMBL:EAW90288.1 xref: UniProtKB:A2T931 xref: UniProtKB:A2T932 xref: UniProtKB:A8K2L1 xref: UniProtKB:A8K9Y3 xref: UniProtKB:Q6GPH4 xref: UniProtKB:Q6MZE8 xref: UniProtKB:Q8N557 xref: UniProtKB:Q99982 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013412 ! XAF1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0041259 name: CNDH2_HUMAN def: "Condensin-2 complex subunit H2" [UniProtKB:Q6IBW4] synonym: "Chromosome-associated protein H2" EXACT [UniProtKB:Q6IBW4] synonym: "hCAP-H2" EXACT [UniProtKB:Q6IBW4] synonym: "Kleisin-beta" EXACT [UniProtKB:Q6IBW4] synonym: "Non-SMC condensin II complex subunit H2" EXACT [UniProtKB:Q6IBW4] xref: EMBL:AAB03345.1 xref: EMBL:AAH00473.1 xref: EMBL:AAH01298.1 xref: EMBL:AAH01509.1 xref: EMBL:AAH01833.1 xref: EMBL:AAH01937.1 xref: EMBL:AAH09441.1 xref: EMBL:AAH14939.2 xref: EMBL:CAA16670.1 xref: EMBL:CAG30490.1 xref: EMBL:EAW73552.1 xref: EMBL:EAW73556.1 xref: UniProtKB:O43788 xref: UniProtKB:Q13391 xref: UniProtKB:Q6IBW4 xref: UniProtKB:Q96C14 xref: UniProtKB:Q96GJ0 xref: UniProtKB:Q9BQ71 xref: UniProtKB:Q9BUT3 xref: UniProtKB:Q9BVD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013385 ! NCAPH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation relationship: transforms_into CCO:B0041287 ! CNDH2_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0041288 ! CNDH2_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0041289 ! CNDH2_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0041290 ! CNDH2_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0041291 ! CNDH2_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0041292 ! CNDH2_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0041293 ! CNDH2_HUMAN-Phosphoserine466 relationship: transforms_into CCO:B0041294 ! CNDH2_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0064415 ! CNDH2_HUMAN-Phosphoserine282 [Term] id: CCO:B0041260 name: CP110_HUMAN def: "Centriolin" [UniProtKB:Q7Z7A1] synonym: "110 kDa centrosomal protein" EXACT [UniProtKB:Q7Z7A1] synonym: "Centrosomal protein 1" EXACT [UniProtKB:Q7Z7A1] xref: EMBL:AAC32373.1 xref: EMBL:AAH02932.1 xref: EMBL:AAH89415.1 xref: EMBL:AAP43846.1 xref: EMBL:AAX35689.1 xref: EMBL:BAB84905.1 xref: EMBL:CAE45965.1 xref: EMBL:CAI12358.1 xref: EMBL:CAM13285.1 xref: UniProtKB:A2A2Y1 xref: UniProtKB:Q3MN79 xref: UniProtKB:Q5FWF8 xref: UniProtKB:Q5JVD0 xref: UniProtKB:Q6MZR3 xref: UniProtKB:Q6PKC1 xref: UniProtKB:Q7Z7A1 xref: UniProtKB:Q8TEP3 xref: UniProtKB:Q9Y489 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004316 ! CEP110_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0003077 ! cell division relationship: transforms_into CCO:B0041295 ! CP110_HUMAN-Phosphotyrosine117 relationship: transforms_into CCO:B0041296 ! CP110_HUMAN-Phosphothreonine286 relationship: transforms_into CCO:B0041297 ! CP110_HUMAN-Phosphothreonine1668 relationship: transforms_into CCO:B0041298 ! CP110_HUMAN-Phosphothreonine1671 [Term] id: CCO:B0041261 name: ERF3B_HUMAN def: "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B" [UniProtKB:Q8IYD1] synonym: "eRF3b" EXACT [UniProtKB:Q8IYD1] synonym: "Eukaryotic peptide chain release factor subunit 3b" EXACT [UniProtKB:Q8IYD1] synonym: "G1 to S phase transition protein 2 homolog" EXACT [UniProtKB:Q8IYD1] xref: EMBL:AAH36077.1 xref: EMBL:BAA91612.1 xref: EMBL:BAB14435.1 xref: EMBL:CAB91089.1 xref: EMBL:CAH71524.1 xref: EMBL:EAW62898.1 xref: UniProtKB:Q8IYD1 xref: UniProtKB:Q9H909 xref: UniProtKB:Q9NVY0 xref: UniProtKB:Q9NY44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008865 ! GSPT2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000318 ! translation release factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0041262 name: CTF8_HUMAN def: "Chromosome transmission fidelity protein 8 homolog" [UniProtKB:Q8WV66] synonym: "hCTF8" EXACT [UniProtKB:Q8WV66] xref: EMBL:AAH18700.4 xref: UniProtKB:A8MYX8 xref: UniProtKB:Q8WV66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014343 ! CHTF8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0041263 name: PSMF1_HUMAN def: "Proteasome inhibitor PI31 subunit" [UniProtKB:Q92530] synonym: "hPI31" EXACT [UniProtKB:Q92530] xref: EMBL:AAI26463.1 xref: EMBL:BAA13603.1 xref: EMBL:CAC10383.1 xref: UniProtKB:A0AVQ9 xref: UniProtKB:Q92530 xref: UniProtKB:Q9H4I1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013407 ! PSMF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008701 ! a2bp1-psmf1 physical interaction relationship: participates_in CCO:I0008766 ! psmf1-a2bp1 physical interaction relationship: participates_in CCO:P0000333 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: participates_in CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: transforms_into CCO:B0069579 ! PSMF1_HUMAN-Phosphoserine252 [Term] id: CCO:B0041264 name: PRDBP_HUMAN def: "Protein kinase C delta-binding protein" [UniProtKB:Q969G5] synonym: "hSRBC" EXACT [UniProtKB:Q969G5] synonym: "Serum deprivation response factor-related gene product that binds to C-kinase" EXACT [UniProtKB:Q969G5] xref: EMBL:AAH11585.1 xref: EMBL:AAK97528.1 xref: EMBL:AAK97572.1 xref: EMBL:EAW68733.1 xref: UniProtKB:Q969G5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013393 ! PRKCDBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0041311 ! PRDBP_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0041312 ! PRDBP_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0041313 ! PRDBP_HUMAN-Phosphoserine166 [Term] id: CCO:B0041265 name: MTBP_HUMAN def: "Mdm2-binding protein" [UniProtKB:Q96DY7] synonym: "hMTBP" EXACT [UniProtKB:Q96DY7] xref: EMBL:AAH13136.1 xref: EMBL:BAB13965.1 xref: EMBL:EAW92006.1 xref: EMBL:EAW92007.1 xref: UniProtKB:Q96DY7 xref: UniProtKB:Q9HA89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013392 ! MTBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0068315 ! MTBP_HUMAN-Phosphoserine639 [Term] id: CCO:B0041266 name: CINP_HUMAN def: "Cyclin-dependent kinase 2-interacting protein" [UniProtKB:Q9BW66] xref: EMBL:AAF44747.1 xref: EMBL:AAF44748.1 xref: EMBL:AAH00600.1 xref: EMBL:BAB71095.1 xref: EMBL:CAG33459.1 xref: EMBL:EAW81785.1 xref: UniProtKB:Q9BW66 xref: UniProtKB:Q9NPF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013384 ! CINP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008675 ! cinp-cluap1 physical interaction relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0041267 name: DMTF1_HUMAN def: "Cyclin-D-binding Myb-like transcription factor 1" [UniProtKB:Q9Y222] synonym: "Cyclin-D-interacting Myb-like protein 1" EXACT [UniProtKB:Q9Y222] synonym: "hDMP1" EXACT [UniProtKB:Q9Y222] synonym: "hDMTF1" EXACT [UniProtKB:Q9Y222] xref: EMBL:AAC33480.1 xref: EMBL:AAD43181.1 xref: EMBL:AAG35613.1 xref: EMBL:AAG35614.1 xref: EMBL:AAH07418.2 xref: EMBL:AAH07447.2 xref: EMBL:AAH29370.1 xref: EMBL:AAH70064.1 xref: EMBL:BAD92467.1 xref: EMBL:EAW76963.1 xref: UniProtKB:Q05C48 xref: UniProtKB:Q59G79 xref: UniProtKB:Q6IS13 xref: UniProtKB:Q969T2 xref: UniProtKB:Q9H2Z2 xref: UniProtKB:Q9H2Z3 xref: UniProtKB:Q9Y222 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013387 ! DMTF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0041276 name: MISSL_HUMAN def: "MAPK-interacting and spindle-stabilizing protein-like" [UniProtKB:Q8NDC0] synonym: "Mitogen-activated protein kinase 1-interacting protein 1-like" EXACT [UniProtKB:Q8NDC0] xref: EMBL:AAH15621.1 xref: EMBL:CAD38959.2 xref: UniProtKB:Q8NDC0 xref: UniProtKB:Q96BG5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013391 ! MAPK1IP1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005736 ! c14orf32-ube2i physical interaction relationship: participates_in CCO:I0015430 ! c14orf32-pdcd6 physical interaction relationship: participates_in CCO:I0015712 ! c14orf32-ewsr1 physical interaction relationship: transforms_into CCO:B0041309 ! MISSL_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0041310 ! MISSL_HUMAN-Phosphoserine15 [Term] id: CCO:B0041277 name: GUSP1_HUMAN def: "Putative beta-glucuronidase-like protein SMA3" [UniProtKB:Q15486] xref: EMBL:AAH50737.1 xref: EMBL:AAP35406.1 xref: EMBL:BAF82521.1 xref: EMBL:BAF98740.1 xref: EMBL:CAA58278.1 xref: EMBL:CAC69829.1 xref: EMBL:CAC69830.1 xref: UniProtKB:A6NLY8 xref: UniProtKB:A8K1B7 xref: UniProtKB:Q15486 xref: UniProtKB:Q969T8 xref: UniProtKB:Q9BUH2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013390 ! GUSBP1_human relationship: has_function CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008052 ! sma3-tp53 physical interaction relationship: participates_in CCO:I0019836 ! sma3-setdb1 physical interaction relationship: participates_in CCO:I0020001 ! fgfr3-sma3 physical interaction [Term] id: CCO:B0041278 name: HBXIP_HUMAN def: "Hepatitis B virus X-interacting protein" [UniProtKB:O43504] synonym: "HBV X-interacting protein" EXACT [UniProtKB:O43504] synonym: "HBX-interacting protein" EXACT [UniProtKB:O43504] xref: EMBL:AAC52032.1 xref: EMBL:AAH62619.2 xref: EMBL:AAV30683.1 xref: EMBL:CAG33147.1 xref: EMBL:CAG46927.1 xref: EMBL:CAH71488.1 xref: UniProtKB:O43504 xref: UniProtKB:Q6IBD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005937 ! HBXIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008116 ! hbxip-rif1 physical interaction relationship: participates_in CCO:I0019729 ! hbxip-eef1a1 physical interaction relationship: participates_in CCO:I0019730 ! hbxip-git1 physical interaction relationship: participates_in CCO:I0019731 ! hbxip-kiaa1377 physical interaction relationship: participates_in CCO:I0020021 ! hbxip-utp14a physical interaction relationship: participates_in CCO:I0020330 ! hbxip-maf1 physical interaction relationship: participates_in CCO:I0020430 ! rabif-hbxip physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: transforms_into CCO:B0041304 ! HBXIP_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0041305 ! HBXIP_HUMAN-Phosphoserine26 [Term] id: CCO:B0041279 name: TM90B_HUMAN def: "Transmembrane protein 90B" [UniProtKB:Q9H7V2] xref: EMBL:AAH30637.1 xref: EMBL:BAB14872.1 xref: EMBL:CAG33606.1 xref: EMBL:CAI15132.1 xref: EMBL:CAI23040.1 xref: UniProtKB:Q6IA30 xref: UniProtKB:Q9H514 xref: UniProtKB:Q9H7V2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013409 ! TMEM90B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008487 ! pfdn1-c20orf39 physical interaction [Term] id: CCO:B0041283 name: ABI1_HUMAN-N-acetylalanine2 def: "Protein ABI1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q8IZP0] xref: UniProtKB:Q8IZP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:B0041284 name: ANXA3_HUMAN-N-acetylalanine2 def: "Protein ANXA3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P12429] xref: UniProtKB:P12429 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001215 ! phospholipase inhibitor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_function CCO:F0004187 ! phospholipase A2 inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006119 ! ANXA3_HUMAN [Term] id: CCO:B0041285 name: CAZA2_HUMAN-N-acetylalanine2 def: "Protein CAZA2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P47755] xref: UniProtKB:P47755 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000542 ! F-actin capping protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0005582 ! CAZA2_HUMAN [Term] id: CCO:B0041286 name: CG020_HUMAN-N-acetylalanine2 def: "Protein CG020_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q7L5D6] xref: UniProtKB:Q7L5D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006174 ! CG020_HUMAN [Term] id: CCO:B0041287 name: CNDH2_HUMAN-Phosphoserine95 def: "Protein CNDH2_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041288 name: CNDH2_HUMAN-Phosphoserine120 def: "Protein CNDH2_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041289 name: CNDH2_HUMAN-Phosphoserine200 def: "Protein CNDH2_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041290 name: CNDH2_HUMAN-Phosphoserine228 def: "Protein CNDH2_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041291 name: CNDH2_HUMAN-Phosphoserine284 def: "Protein CNDH2_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041292 name: CNDH2_HUMAN-Phosphoserine319 def: "Protein CNDH2_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041293 name: CNDH2_HUMAN-Phosphoserine466 def: "Protein CNDH2_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041294 name: CNDH2_HUMAN-Phosphoserine492 def: "Protein CNDH2_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0041295 name: CP110_HUMAN-Phosphotyrosine117 def: "Protein CP110_HUMAN with the residue 117 substituted with Phosphotyrosine" [UniProtKB:Q7Z7A1] xref: UniProtKB:Q7Z7A1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041260 ! CP110_HUMAN [Term] id: CCO:B0041296 name: CP110_HUMAN-Phosphothreonine286 def: "Protein CP110_HUMAN with the residue 286 substituted with Phosphothreonine" [UniProtKB:Q7Z7A1] xref: UniProtKB:Q7Z7A1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041260 ! CP110_HUMAN [Term] id: CCO:B0041297 name: CP110_HUMAN-Phosphothreonine1668 def: "Protein CP110_HUMAN with the residue 1668 substituted with Phosphothreonine" [UniProtKB:Q7Z7A1] xref: UniProtKB:Q7Z7A1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0041260 ! CP110_HUMAN [Term] id: CCO:B0041298 name: CP110_HUMAN-Phosphothreonine1671 def: "Protein CP110_HUMAN with the residue 1671 substituted with Phosphothreonine" [UniProtKB:Q7Z7A1] xref: UniProtKB:Q7Z7A1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041260 ! CP110_HUMAN [Term] id: CCO:B0041299 name: EI2BG_HUMAN-N-acetylmethionine1 def: "Protein EI2BG_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q9NR50] xref: UniProtKB:Q9NR50 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000417 ! eukaryotic translation initiation factor 2B complex relationship: transformation_of CCO:B0005834 ! EI2BG_HUMAN [Term] id: CCO:B0041300 name: EIF3E_HUMAN-N-acetylalanine2 def: "Protein EIF3E_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P60228] xref: UniProtKB:P60228 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:B0041301 name: EIF3J_HUMAN-N-acetylalanine2 def: "Protein EIF3J_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O75822] xref: UniProtKB:O75822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:B0041302 name: ERC6L_HUMAN-Phosphoserine1021 def: "Protein ERC6L_HUMAN with the residue 1021 substituted with Phosphoserine" [UniProtKB:Q2NKX8] comment: By similarity xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0041303 name: ERC6L_HUMAN-Phosphothreonine1063 def: "Protein ERC6L_HUMAN with the residue 1063 substituted with Phosphothreonine" [UniProtKB:Q2NKX8] comment: by PLK1; xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0041304 name: HBXIP_HUMAN-N-acetylmethionine1 def: "Protein HBXIP_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:O43504] xref: UniProtKB:O43504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:B0041305 name: HBXIP_HUMAN-Phosphoserine26 def: "Protein HBXIP_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:O43504] xref: UniProtKB:O43504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:B0041306 name: HMGA2_HUMAN-Phosphoserine105 def: "Protein HMGA2_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:P52926] comment: By similarity xref: UniProtKB:P52926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041249 ! HMGA2_HUMAN [Term] id: CCO:B0041307 name: HNRPK_HUMAN-N-acetylmethionine1 def: "Protein HNRPK_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P61978] xref: UniProtKB:P61978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:B0041308 name: K2C6A_HUMAN-N-acetylalanine2 def: "Protein K2C6A_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P02538] xref: UniProtKB:P02538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005821 ! K2C6A_HUMAN [Term] id: CCO:B0041309 name: MISSL_HUMAN-N-acetylserine2 def: "Protein MISSL_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q8NDC0] xref: UniProtKB:Q8NDC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041276 ! MISSL_HUMAN [Term] id: CCO:B0041310 name: MISSL_HUMAN-Phosphoserine15 def: "Protein MISSL_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q8NDC0] xref: UniProtKB:Q8NDC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041276 ! MISSL_HUMAN [Term] id: CCO:B0041311 name: PRDBP_HUMAN-Phosphoserine4 def: "Protein PRDBP_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:Q969G5] xref: UniProtKB:Q969G5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041264 ! PRDBP_HUMAN [Term] id: CCO:B0041312 name: PRDBP_HUMAN-Phosphoserine165 def: "Protein PRDBP_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q969G5] xref: UniProtKB:Q969G5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041264 ! PRDBP_HUMAN [Term] id: CCO:B0041313 name: PRDBP_HUMAN-Phosphoserine166 def: "Protein PRDBP_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q969G5] xref: UniProtKB:Q969G5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041264 ! PRDBP_HUMAN [Term] id: CCO:B0041314 name: PRS6A_HUMAN-N-acetylmethionine1 def: "Protein PRS6A_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P17980] xref: UniProtKB:P17980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041242 ! PRS6A_HUMAN [Term] id: CCO:B0041315 name: PRS6A_HUMAN-Phosphoserine9 def: "Protein PRS6A_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P17980] xref: UniProtKB:P17980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: transformation_of CCO:B0041242 ! PRS6A_HUMAN [Term] id: CCO:B0041316 name: PRS6B_HUMAN-N-acetylmethionine1 def: "Protein PRS6B_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P43686] xref: UniProtKB:P43686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041247 ! PRS6B_HUMAN [Term] id: CCO:B0041317 name: PRS8_HUMAN-N-acetylalanine2 def: "Protein PRS8_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62195] xref: UniProtKB:P62195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041253 ! PRS8_HUMAN [Term] id: CCO:B0041318 name: PSA2_HUMAN-N-acetylalanine2 def: "Protein PSA2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P25787] comment: By similarity xref: UniProtKB:P25787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:B0041319 name: PSA2_HUMAN-Phosphotyrosine24 def: "Protein PSA2_HUMAN with the residue 24 substituted with Phosphotyrosine" [UniProtKB:P25787] xref: UniProtKB:P25787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:B0041320 name: PSA2_HUMAN-Phosphotyrosine76 def: "Protein PSA2_HUMAN with the residue 76 substituted with Phosphotyrosine" [UniProtKB:P25787] xref: UniProtKB:P25787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:B0041321 name: PSA2_HUMAN-Phosphotyrosine98 def: "Protein PSA2_HUMAN with the residue 98 substituted with Phosphotyrosine" [UniProtKB:P25787] xref: UniProtKB:P25787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:B0041322 name: PSA2_HUMAN-Phosphotyrosine121 def: "Protein PSA2_HUMAN with the residue 121 substituted with Phosphotyrosine" [UniProtKB:P25787] comment: By similarity xref: UniProtKB:P25787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:B0041323 name: PSA2_HUMAN-Nitrated tyrosine229 def: "Protein PSA2_HUMAN with the residue 229 substituted with Nitrated tyrosine" [UniProtKB:P25787] xref: UniProtKB:P25787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:B0041324 name: PSA4_HUMAN-Phosphoserine13 def: "Protein PSA4_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P25789] xref: UniProtKB:P25789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:B0041325 name: PSA4_HUMAN-Phosphoserine75 def: "Protein PSA4_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:P25789] xref: UniProtKB:P25789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:B0041326 name: PSA6_HUMAN-Phosphotyrosine159 def: "Protein PSA6_HUMAN with the residue 159 substituted with Phosphotyrosine" [UniProtKB:P60900] comment: By similarity xref: UniProtKB:P60900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:B0041327 name: PSB4_HUMAN-Phosphotyrosine102 def: "Protein PSB4_HUMAN with the residue 102 substituted with Phosphotyrosine" [UniProtKB:P28070] xref: UniProtKB:P28070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041245 ! PSB4_HUMAN [Term] id: CCO:B0041328 name: PSD10_HUMAN-N-acetylmethionine1 def: "Protein PSD10_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:O75832] xref: UniProtKB:O75832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: located_in CCO:C0002079 ! proteasome regulatory particle relationship: transformation_of CCO:B0041240 ! PSD10_HUMAN [Term] id: CCO:B0041329 name: PSDE_HUMAN-Phosphoserine150 def: "Protein PSDE_HUMAN with the residue 150 substituted with Phosphoserine" [UniProtKB:O00487] xref: UniProtKB:O00487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023606 ! PSDE_HUMAN [Term] id: CCO:B0041330 name: PSMD4_HUMAN-Phosphothreonine250 def: "Protein PSMD4_HUMAN with the residue 250 substituted with Phosphothreonine" [UniProtKB:P55036] comment: By similarity xref: UniProtKB:P55036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041250 ! PSMD4_HUMAN [Term] id: CCO:B0041331 name: PSMD4_HUMAN-Phosphoserine256 def: "Protein PSMD4_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:P55036] comment: By similarity xref: UniProtKB:P55036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041250 ! PSMD4_HUMAN [Term] id: CCO:B0041332 name: PSMD4_HUMAN-Phosphoserine266 def: "Protein PSMD4_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:P55036] xref: UniProtKB:P55036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041250 ! PSMD4_HUMAN [Term] id: CCO:B0041333 name: PSMD4_HUMAN-Phosphoserine358 def: "Protein PSMD4_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:P55036] xref: UniProtKB:P55036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002078 ! proteasome complex relationship: transformation_of CCO:B0041250 ! PSMD4_HUMAN [Term] id: CCO:B0041334 name: PSMD4_HUMAN-Phosphoserine361 def: "Protein PSMD4_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:P55036] xref: UniProtKB:P55036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041250 ! PSMD4_HUMAN [Term] id: CCO:B0041335 name: PSMD5_HUMAN-N-acetylalanine2 def: "Protein PSMD5_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q16401] xref: UniProtKB:Q16401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041255 ! PSMD5_HUMAN [Term] id: CCO:B0041336 name: PSMD9_HUMAN-Phosphoserine129 def: "Protein PSMD9_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:O00233] comment: By similarity xref: UniProtKB:O00233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041239 ! PSMD9_HUMAN [Term] id: CCO:B0041337 name: PSME3_HUMAN-Phosphothreonine205 def: "Protein PSME3_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:P61289] comment: By similarity xref: UniProtKB:P61289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:B0041338 name: PSME3_HUMAN-Phosphothreonine207 def: "Protein PSME3_HUMAN with the residue 207 substituted with Phosphothreonine" [UniProtKB:P61289] comment: By similarity xref: UniProtKB:P61289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:B0041339 name: RBX1_HUMAN-N-acetylalanine2 def: "Protein RBX1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62877] xref: UniProtKB:P62877 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:B0041340 name: RUVB2_HUMAN-N-acetylalanine2 def: "Protein RUVB2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y230] xref: UniProtKB:Q9Y230 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005364 ! RUVB2_HUMAN [Term] id: CCO:B0041341 name: SSRP1_HUMAN-N-acetylalanine2 def: "Protein SSRP1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0041342 name: SUGT1_HUMAN-N-acetylalanine2 def: "Protein SUGT1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y2Z0] xref: UniProtKB:Q9Y2Z0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002252 ! SUGT1_HUMAN [Term] id: CCO:B0041343 name: SYK_HUMAN-N-acetylalanine2 def: "Protein SYK_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q15046] xref: UniProtKB:Q15046 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006279 ! SYK_HUMAN [Term] id: CCO:B0041344 name: TCPE_HUMAN-N-acetylalanine2 def: "Protein TCPE_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P48643] xref: UniProtKB:P48643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000400 ! chaperonin-containing T-complex relationship: transformation_of CCO:B0005291 ! TCPE_HUMAN [Term] id: CCO:B0041345 name: ZW10_HUMAN-N-acetylalanine2 def: "Protein ZW10_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O43264] xref: UniProtKB:O43264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001387 ! ZW10_HUMAN [Term] id: CCO:B0041368 name: RHG27_HUMAN def: "Rho GTPase-activating protein 27" [UniProtKB:Q6ZUM4] synonym: "CIN85-associated multi-domain-containing Rho GTPase-activating protein 1" EXACT [UniProtKB:Q6ZUM4] synonym: "Rho-type GTPase-activating protein 27" EXACT [UniProtKB:Q6ZUM4] xref: EMBL:AAG23796.1 xref: EMBL:AAH67345.1 xref: EMBL:AAI01389.1 xref: EMBL:AAI01390.1 xref: EMBL:AAI01391.1 xref: EMBL:AAI01392.3 xref: EMBL:BAC86196.1 xref: EMBL:BAF83339.1 xref: UniProtKB:A4FU35 xref: UniProtKB:A8K3N5 xref: UniProtKB:Q494U0 xref: UniProtKB:Q6NWZ8 xref: UniProtKB:Q6ZUM4 xref: UniProtKB:Q8WY58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013627 ! ARHGAP27_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002157 ! positive regulation of Cdc42 GTPase activity relationship: transforms_into CCO:B0043357 ! RHG27_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0043358 ! RHG27_HUMAN-Phosphotyrosine228 relationship: transforms_into CCO:B0043359 ! RHG27_HUMAN-Phosphoserine638 [Term] id: CCO:B0041371 name: RHG15_HUMAN def: "Rho GTPase-activating protein 15" [UniProtKB:Q53QZ3] synonym: "ArhGAP15" EXACT [UniProtKB:Q53QZ3] synonym: "Rho-type GTPase-activating protein 15" EXACT [UniProtKB:Q53QZ3] xref: EMBL:AAF67618.1 xref: EMBL:AAF67633.1 xref: EMBL:AAF87324.1 xref: EMBL:AAH16701.1 xref: EMBL:AAH38976.2 xref: EMBL:AAO34684.1 xref: EMBL:AAX82009.1 xref: EMBL:AAX93158.1 xref: EMBL:AAX93160.1 xref: EMBL:AAX93245.1 xref: EMBL:AAY14811.1 xref: EMBL:AAY24215.1 xref: EMBL:EAX11590.1 xref: UniProtKB:Q53QZ3 xref: UniProtKB:Q53R36 xref: UniProtKB:Q53RD7 xref: UniProtKB:Q53RT6 xref: UniProtKB:Q53SX9 xref: UniProtKB:Q584N9 xref: UniProtKB:Q6PJE6 xref: UniProtKB:Q86WP1 xref: UniProtKB:Q8IXX1 xref: UniProtKB:Q9NRL8 xref: UniProtKB:Q9NZ77 xref: UniProtKB:Q9NZ91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013626 ! ARHGAP15_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041373 name: Q1RLN5_HUMAN def: "ARHGAP12 protein" [UniProtKB:Q1RLN5] xref: EMBL:AAI15363.1 xref: EMBL:AAI15364.1 xref: UniProtKB:Q1RLN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013625 ! ARHGAP12_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041376 name: RHG12_HUMAN def: "Rho GTPase-activating protein 12" [UniProtKB:Q8IWW6] synonym: "Rho-type GTPase-activating protein 12" EXACT [UniProtKB:Q8IWW6] xref: EMBL:AAH51811.1 xref: EMBL:AAK52311.1 xref: EMBL:AAK52312.1 xref: EMBL:CAB70766.1 xref: EMBL:CAD38926.2 xref: UniProtKB:Q86UB3 xref: UniProtKB:Q8IWW6 xref: UniProtKB:Q8IWW7 xref: UniProtKB:Q8N3L1 xref: UniProtKB:Q9NT76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013625 ! ARHGAP12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043350 ! RHG12_HUMAN-Phosphoserine201 relationship: transforms_into CCO:B0043351 ! RHG12_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0043352 ! RHG12_HUMAN-Phosphothreonine231 relationship: transforms_into CCO:B0043353 ! RHG12_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0043354 ! RHG12_HUMAN-Phosphotyrosine243 relationship: transforms_into CCO:B0043355 ! RHG12_HUMAN-Phosphothreonine521 relationship: transforms_into CCO:B0043356 ! RHG12_HUMAN-Phosphoserine592 relationship: transforms_into CCO:B0069950 ! RHG12_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0069951 ! RHG12_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0069952 ! RHG12_HUMAN-Phosphothreonine230 [Term] id: CCO:B0041399 name: FLNC_HUMAN def: "Filamin-C" [UniProtKB:Q14315] synonym: "ABP-280-like protein" EXACT [UniProtKB:Q14315] synonym: "ABP-L" EXACT [UniProtKB:Q14315] synonym: "Actin-binding-like protein" EXACT [UniProtKB:Q14315] synonym: "Filamin-2" EXACT [UniProtKB:Q14315] synonym: "Gamma-filamin" EXACT [UniProtKB:Q14315] synonym: "Protein FLNc" EXACT [UniProtKB:Q14315] xref: EMBL:AAD12245.1 xref: EMBL:AAF67190.1 xref: EMBL:AAF68195.1 xref: EMBL:AAF80245.1 xref: EMBL:CAA49688.1 xref: EMBL:CAA49689.1 xref: EMBL:CAB46442.1 xref: EMBL:CAB51535.1 xref: UniProtKB:O95303 xref: UniProtKB:Q07985 xref: UniProtKB:Q14315 xref: UniProtKB:Q9NS12 xref: UniProtKB:Q9NYE5 xref: UniProtKB:Q9UMR8 xref: UniProtKB:Q9Y503 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013540 ! FLNC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015912 ! adra1a-fnlc-1 physical interaction relationship: participates_in CCO:I0017677 ! adra1b-fnlc-1 physical interaction relationship: participates_in CCO:I0017758 ! adra1d-fnlc-1 physical interaction relationship: transforms_into CCO:B0043279 ! FLNC_HUMAN-Phosphoserine1161 relationship: transforms_into CCO:B0066213 ! FLNC_HUMAN-Phosphotyrosine2683 [Term] id: CCO:B0041401 name: FLNA_HUMAN def: "Filamin-A" [UniProtKB:P21333] synonym: "ABP-280" EXACT [UniProtKB:P21333] synonym: "Actin-binding protein 280" EXACT [UniProtKB:P21333] synonym: "Alpha-filamin" EXACT [UniProtKB:P21333] synonym: "Endothelial actin-binding protein" EXACT [UniProtKB:P21333] synonym: "Filamin-1" EXACT [UniProtKB:P21333] synonym: "Non-muscle filamin" EXACT [UniProtKB:P21333] xref: EMBL:AAA92644.1 xref: EMBL:BAC03408.1 xref: EMBL:CAA37495.1 xref: EMBL:CAA49687.1 xref: EMBL:CAA49690.1 xref: UniProtKB:P21333 xref: UniProtKB:Q8NF52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013538 ! FLNA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015855 ! arhgap24-flna-6 physical interaction relationship: participates_in CCO:I0015990 ! arhgap24-flna-2 physical interaction relationship: participates_in CCO:I0016323 ! arhgap24-flna-3 physical interaction relationship: participates_in CCO:I0016324 ! arhgap24-flna-4 physical interaction relationship: participates_in CCO:I0016462 ! ikbkb-flna physical interaction relationship: participates_in CCO:I0016544 ! ikbkg-flna physical interaction relationship: participates_in CCO:I0016636 ! map3k1-flna physical interaction relationship: participates_in CCO:I0016739 ! map3k3-flna physical interaction relationship: participates_in CCO:I0016954 ! q9nyj8-flna physical interaction relationship: participates_in CCO:I0017048 ! tnfrsf1b-flna physical interaction relationship: participates_in CCO:I0017769 ! arhgap24-flna-1 physical interaction relationship: participates_in CCO:I0018083 ! flna-flnb-6 colocalization relationship: participates_in CCO:I0018388 ! arhgap24-flna-5 colocalization relationship: participates_in CCO:I0018677 ! flna-flnb-1 physical interaction relationship: participates_in CCO:I0018678 ! flna-flnb-2 physical interaction relationship: participates_in CCO:I0018681 ! flna-flnb-3 physical interaction relationship: participates_in CCO:I0018682 ! flna-flnb-4 physical interaction relationship: participates_in CCO:I0019288 ! flna-flnb-5 physical interaction relationship: participates_in CCO:I0019500 ! irk2-flna-3 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: transforms_into CCO:B0043264 ! FLNA_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0043265 ! FLNA_HUMAN-Phosphotyrosine1047 relationship: transforms_into CCO:B0043266 ! FLNA_HUMAN-Phosphoserine1084 relationship: transforms_into CCO:B0043267 ! FLNA_HUMAN-Phosphothreonine1089 relationship: transforms_into CCO:B0043268 ! FLNA_HUMAN-Phosphothreonine1286 relationship: transforms_into CCO:B0043269 ! FLNA_HUMAN-Phosphoserine1459 relationship: transforms_into CCO:B0043270 ! FLNA_HUMAN-Phosphoserine1533 relationship: transforms_into CCO:B0043271 ! FLNA_HUMAN-Phosphoserine2152 relationship: transforms_into CCO:B0043272 ! FLNA_HUMAN-Phosphoserine2158 relationship: transforms_into CCO:B0043273 ! FLNA_HUMAN-Phosphoserine2284 relationship: transforms_into CCO:B0043274 ! FLNA_HUMAN-Phosphoserine2327 relationship: transforms_into CCO:B0066210 ! FLNA_HUMAN-Phosphotyrosine373 relationship: transforms_into CCO:B0066211 ! FLNA_HUMAN-Phosphotyrosine1604 relationship: transforms_into CCO:B0066212 ! FLNA_HUMAN-Phosphotyrosine2388 [Term] id: CCO:B0041405 name: Q60FE5_HUMAN def: "Filamin A" [UniProtKB:Q60FE5] xref: EMBL:BAD52436.1 xref: EMBL:BAG48303.1 xref: EMBL:BAG48305.1 xref: UniProtKB:Q60FE5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013538 ! FLNA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction [Term] id: CCO:B0041417 name: FLNB_HUMAN def: "Filamin-B" [UniProtKB:O75369] synonym: "ABP-278" EXACT [UniProtKB:O75369] synonym: "ABP-280 homolog" EXACT [UniProtKB:O75369] synonym: "Actin-binding-like protein" EXACT [UniProtKB:O75369] synonym: "Beta-filamin" EXACT [UniProtKB:O75369] synonym: "Fh1" EXACT [UniProtKB:O75369] synonym: "Filamin 3" EXACT [UniProtKB:O75369] synonym: "Filamin homolog 1" EXACT [UniProtKB:O75369] synonym: "FLN-B" EXACT [UniProtKB:O75369] synonym: "Thyroid autoantigen" EXACT [UniProtKB:O75369] synonym: "Truncated ABP" EXACT [UniProtKB:O75369] synonym: "Truncated actin-binding protein" EXACT [UniProtKB:O75369] xref: EMBL:AAA35505.1 xref: EMBL:AAC33845.1 xref: EMBL:AAC39842.1 xref: EMBL:AAF72339.1 xref: EMBL:AAF97046.1 xref: EMBL:AAL68440.1 xref: EMBL:AAL68441.1 xref: EMBL:AAL68442.1 xref: EMBL:AAL68443.1 xref: EMBL:BAD93126.1 xref: EMBL:CAB70818.1 xref: EMBL:CAE46040.1 xref: UniProtKB:O75369 xref: UniProtKB:Q13706 xref: UniProtKB:Q59EC2 xref: UniProtKB:Q6MZJ1 xref: UniProtKB:Q8WXS9 xref: UniProtKB:Q8WXT0 xref: UniProtKB:Q8WXT1 xref: UniProtKB:Q8WXT2 xref: UniProtKB:Q9NRB5 xref: UniProtKB:Q9NT26 xref: UniProtKB:Q9UEV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013539 ! FLNB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0018083 ! flna-flnb-6 colocalization relationship: participates_in CCO:I0018677 ! flna-flnb-1 physical interaction relationship: participates_in CCO:I0018678 ! flna-flnb-2 physical interaction relationship: participates_in CCO:I0018679 ! flnb-flnb-1 physical interaction relationship: participates_in CCO:I0018680 ! flnb-flnb-2 physical interaction relationship: participates_in CCO:I0018681 ! flna-flnb-3 physical interaction relationship: participates_in CCO:I0018682 ! flna-flnb-4 physical interaction relationship: participates_in CCO:I0018683 ! flnb-flnb-4 physical interaction relationship: participates_in CCO:I0018684 ! flnb-flnb-3 physical interaction relationship: participates_in CCO:I0019288 ! flna-flnb-5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043275 ! FLNB_HUMAN-Phosphoserine658 relationship: transforms_into CCO:B0043276 ! FLNB_HUMAN-Phosphoserine983 relationship: transforms_into CCO:B0043277 ! FLNB_HUMAN-Phosphoserine2369 relationship: transforms_into CCO:B0043278 ! FLNB_HUMAN-Phosphotyrosine2502 [Term] id: CCO:B0041421 name: STAR8_HUMAN def: "StAR-related lipid transfer protein 8" [UniProtKB:Q92502] synonym: "Deleted in liver cancer 3" EXACT [UniProtKB:Q92502] synonym: "DLC-3" EXACT [UniProtKB:Q92502] synonym: "StARD8" EXACT [UniProtKB:Q92502] synonym: "START domain-containing protein 8" EXACT [UniProtKB:Q92502] synonym: "START-GAP3" EXACT [UniProtKB:Q92502] xref: EMBL:AAH35587.1 xref: EMBL:BAA11506.2 xref: EMBL:BAF84436.1 xref: EMBL:CAH18253.1 xref: EMBL:CAI41586.1 xref: EMBL:EAX05374.1 xref: UniProtKB:A8K6T2 xref: UniProtKB:Q5JST0 xref: UniProtKB:Q68DG7 xref: UniProtKB:Q92502 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013638 ! STARD8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043382 ! STAR8_HUMAN-Phosphoserine238 [Term] id: CCO:B0041436 name: IF2A_HUMAN def: "Eukaryotic translation initiation factor 2 subunit 1" [UniProtKB:P05198] synonym: "eIF-2-alpha" EXACT [UniProtKB:P05198] synonym: "EIF-2A" EXACT [UniProtKB:P05198] synonym: "EIF-2alpha" EXACT [UniProtKB:P05198] synonym: "Eukaryotic translation initiation factor 2 subunit alpha" EXACT [UniProtKB:P05198] xref: EMBL:AAA52373.1 xref: EMBL:AAH02513.1 xref: UniProtKB:P05198 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013564 ! EIF2S1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0002243 ! regulation of translational initiation in response to stress relationship: transforms_into CCO:B0043290 ! IF2A_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0043291 ! IF2A_HUMAN-Phosphoserine52 [Term] id: CCO:B0041474 name: B1AHC4_HUMAN def: "Rho GTPase activating protein 8" [UniProtKB:B1AHC4] xref: EMBL:CAQ06716.1 xref: EMBL:CAQ07748.1 xref: EMBL:CAQ09259.1 xref: UniProtKB:B1AHC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005481 ! ARHGAP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041516 name: ANK2_HUMAN def: "Ankyrin-2" [UniProtKB:Q01484] synonym: "Ankyrin-B" EXACT [UniProtKB:Q01484] synonym: "Brain ankyrin" EXACT [UniProtKB:Q01484] synonym: "Non-erythroid ankyrin" EXACT [UniProtKB:Q01484] xref: EMBL:AAA62828.1 xref: EMBL:CAA40278.1 xref: EMBL:CAA40279.2 xref: EMBL:CAB42644.1 xref: UniProtKB:Q01484 xref: UniProtKB:Q01485 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013480 ! ANK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017423 ! tnik-ank2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043194 ! ANK2_HUMAN-Phosphoserine911 relationship: transforms_into CCO:B0043195 ! ANK2_HUMAN-Phosphoserine1475 relationship: transforms_into CCO:B0043196 ! ANK2_HUMAN-Phosphothreonine1490 relationship: transforms_into CCO:B0043197 ! ANK2_HUMAN-Phosphothreonine2550 [Term] id: CCO:B0041521 name: Q7Z3L5_HUMAN def: "Putative uncharacterized protein DKFZp686H0688" [UniProtKB:Q7Z3L5] xref: EMBL:CAD97827.1 xref: UniProtKB:Q7Z3L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013721 ! DKFZp686H0688_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041523 name: ANK1_HUMAN def: "Ankyrin-1" [UniProtKB:P16157] synonym: "Ankyrin-R" EXACT [UniProtKB:P16157] synonym: "Erythrocyte ankyrin" EXACT [UniProtKB:P16157] xref: EMBL:AAA51732.1 xref: EMBL:AAB47805.1 xref: EMBL:AAC01950.1 xref: EMBL:AAH30957.1 xref: EMBL:BAD92655.1 xref: EMBL:CAA34610.1 xref: EMBL:CAA34611.1 xref: UniProtKB:A6NJ23 xref: UniProtKB:O43400 xref: UniProtKB:P16157 xref: UniProtKB:Q13768 xref: UniProtKB:Q59FP2 xref: UniProtKB:Q8N604 xref: UniProtKB:Q99407 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013479 ! ANK1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004448 ! spectrin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000802 ! sarcoplasmic reticulum relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043190 ! ANK1_HUMAN-Phosphoserine856 relationship: transforms_into CCO:B0043191 ! ANK1_HUMAN-Phosphotyrosine1073 relationship: transforms_into CCO:B0043192 ! ANK1_HUMAN-Phosphothreonine1684 relationship: transforms_into CCO:B0043193 ! ANK1_HUMAN-Phosphoserine1686 [Term] id: CCO:B0041526 name: ANK3_HUMAN def: "Ankyrin-3" [UniProtKB:Q12955] synonym: "ANK-3" EXACT [UniProtKB:Q12955] synonym: "Ankyrin-G" EXACT [UniProtKB:Q12955] xref: EMBL:AAA64834.1 xref: UniProtKB:Q12955 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013481 ! ANK3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043198 ! ANK3_HUMAN-Phosphoserine4298 relationship: transforms_into CCO:B0065626 ! ANK3_HUMAN-Phosphotyrosine533 relationship: transforms_into CCO:B0065627 ! ANK3_HUMAN-Phosphoserine1459 [Term] id: CCO:B0041528 name: Q7Z3G4_HUMAN def: "Putative uncharacterized protein DKFZp686P17114" [UniProtKB:Q7Z3G4] xref: EMBL:CAD97900.2 xref: UniProtKB:Q7Z3G4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013720 ! DKFZp686P17114_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041531 name: Q5CZH9_HUMAN def: "Putative uncharacterized protein DKFZp686I225" [UniProtKB:Q5CZH9] xref: EMBL:CAI56716.1 xref: UniProtKB:Q5CZH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013699 ! DKFZp686I225_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041532 name: B1AQT2_HUMAN def: "Ankyrin 3, node of Ranvier (Ankyrin G)" [UniProtKB:B1AQT2] xref: EMBL:CAI40521.1 xref: UniProtKB:B1AQT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013481 ! ANK3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041548 name: SYF1_HUMAN def: "Pre-mRNA-splicing factor SYF1" [UniProtKB:Q9HCS7] synonym: "Protein HCNP" EXACT [UniProtKB:Q9HCS7] synonym: "XPA-binding protein 2" EXACT [UniProtKB:Q9HCS7] xref: EMBL:AAF86951.1 xref: EMBL:AAG23770.1 xref: EMBL:AAH07208.1 xref: EMBL:AAH08778.1 xref: EMBL:AAN17847.1 xref: EMBL:BAA86491.1 xref: EMBL:BAB15807.1 xref: EMBL:BAB84861.1 xref: UniProtKB:Q8TET6 xref: UniProtKB:Q96HB0 xref: UniProtKB:Q96IW0 xref: UniProtKB:Q9HCS7 xref: UniProtKB:Q9NRG6 xref: UniProtKB:Q9ULP3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008356 ! XAB2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0015630 ! ppie-xab2 physical interaction relationship: participates_in CCO:I0015884 ! xab2-polr2a-1 physical interaction relationship: participates_in CCO:I0015885 ! polr2a-xab2-1 physical interaction relationship: participates_in CCO:I0018426 ! polr2a-ercc6-1 physical interaction relationship: participates_in CCO:I0018580 ! xab2-ckn1-1 physical interaction relationship: participates_in CCO:I0018581 ! ckn1-xab2-1 physical interaction relationship: participates_in CCO:I0018764 ! xab2-ckn1-2 physical interaction relationship: participates_in CCO:I0018765 ! xab2-ercc6-1 physical interaction relationship: transforms_into CCO:B0071039 ! SYF1_HUMAN-Phosphoserine851 [Term] id: CCO:B0041576 name: WTIP_HUMAN def: "Wilms tumor protein 1-interacting protein" [UniProtKB:A6NIX2] synonym: "WT1-interacting protein" EXACT [UniProtKB:A6NIX2] xref: UniProtKB:A6NIX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008436 ! WTIP_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0041586 name: B0ZTD4_HUMAN def: "Forkhead box A2 (Forkhead box A2, isoform CRA_b)" [UniProtKB:B0ZTD4] xref: EMBL:ACA06111.1 xref: EMBL:EAX10175.1 xref: UniProtKB:B0ZTD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007533 ! FOXA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0041593 name: NCOA4_HUMAN def: "Nuclear receptor coactivator 4" [UniProtKB:Q13772] synonym: "70 kDa androgen receptor coactivator" EXACT [UniProtKB:Q13772] synonym: "70 kDa AR-activator" EXACT [UniProtKB:Q13772] synonym: "NCoA-4" EXACT [UniProtKB:Q13772] synonym: "Ret-activating protein ELE1" EXACT [UniProtKB:Q13772] xref: EMBL:AAC37591.1 xref: EMBL:AAH01562.1 xref: EMBL:CAA50536.1 xref: EMBL:CAA54673.1 xref: EMBL:CAB82390.1 xref: UniProtKB:Q13772 xref: UniProtKB:Q14239 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013602 ! NCOA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017613 ! atxn2-ncoa4 physical interaction relationship: participates_in CCO:I0018751 ! ar-ncoa4-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0043336 ! NCOA4_HUMAN-Phosphoserine456 [Term] id: CCO:B0041601 name: A1L382_HUMAN xref: UniProtKB:A1L382 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0041605 name: A1L381_HUMAN xref: UniProtKB:A1L381 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0041664 name: PLF4_HUMAN def: "Platelet factor 4 precursor" [UniProtKB:P02776] synonym: "C-X-C motif chemokine 4" EXACT [UniProtKB:P02776] synonym: "Iroplact" EXACT [UniProtKB:P02776] synonym: "Oncostatin-A" EXACT [UniProtKB:P02776] synonym: "PF-4" EXACT [UniProtKB:P02776] xref: EMBL:AAA60066.1 xref: EMBL:AAH93965.1 xref: EMBL:AAI12094.1 xref: EMBL:AAK29643.1 xref: EMBL:AAY41003.1 xref: EMBL:CAG28605.1 xref: UniProtKB:P02776 xref: UniProtKB:Q53X61 xref: UniProtKB:Q9UC64 xref: UniProtKB:Q9UC65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013619 ! PF4_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002467 ! negative regulation of megakaryocyte differentiation [Term] id: CCO:B0041666 name: CXCL5_HUMAN def: "C-X-C motif chemokine 5 precursor" [UniProtKB:P42830] synonym: "ENA-78(1-78)" EXACT [UniProtKB:P42830] synonym: "Epithelial-derived neutrophil-activating protein 78" EXACT [UniProtKB:P42830] synonym: "Neutrophil-activating peptide ENA-78" EXACT [UniProtKB:P42830] synonym: "Small-inducible cytokine B5" EXACT [UniProtKB:P42830] xref: EMBL:AAA62475.1 xref: EMBL:AAA86426.1 xref: EMBL:AAH08376.1 xref: EMBL:AAK29641.1 xref: EMBL:CAA55355.1 xref: EMBL:CAC42884.1 xref: UniProtKB:P42830 xref: UniProtKB:Q96QE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013519 ! CXCL5_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0041668 name: GROA_HUMAN def: "Growth-regulated alpha protein precursor" [UniProtKB:P09341] synonym: "C-X-C motif chemokine 1" EXACT [UniProtKB:P09341] synonym: "GRO-alpha(1-73)" EXACT [UniProtKB:P09341] synonym: "Melanoma growth stimulatory activity" EXACT [UniProtKB:P09341] synonym: "MGSA" EXACT [UniProtKB:P09341] synonym: "NAP-3" EXACT [UniProtKB:P09341] synonym: "Neutrophil-activating protein 3" EXACT [UniProtKB:P09341] xref: EMBL:AAA35933.1 xref: EMBL:AAH11976.1 xref: EMBL:AAP35526.1 xref: EMBL:CAA31027.1 xref: EMBL:CAA38361.1 xref: UniProtKB:P09341 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013559 ! CXCL1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0041670 name: CXCL6_HUMAN def: "C-X-C motif chemokine 6 precursor" [UniProtKB:P80162] synonym: "Chemokine alpha 3" EXACT [UniProtKB:P80162] synonym: "CKA-3" EXACT [UniProtKB:P80162] synonym: "GCP-2" EXACT [UniProtKB:P80162] synonym: "Granulocyte chemotactic protein 2" EXACT [UniProtKB:P80162] synonym: "Small-inducible cytokine B6" EXACT [UniProtKB:P80162] xref: EMBL:AAC51338.1 xref: EMBL:AAD00506.1 xref: EMBL:AAH13744.1 xref: EMBL:AAY40939.1 xref: EMBL:CAA70023.1 xref: UniProtKB:P80162 xref: UniProtKB:Q4W5D4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013520 ! CXCL6_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041672 name: BNIPL_HUMAN def: "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein" [UniProtKB:Q7Z465] xref: EMBL:AAG22484.1 xref: EMBL:AAH27868.2 xref: EMBL:AAH74779.3 xref: EMBL:AAH74780.3 xref: EMBL:AAK54348.1 xref: EMBL:AAL85483.1 xref: EMBL:AAL85484.1 xref: EMBL:CAI13344.1 xref: EMBL:CAI13347.1 xref: UniProtKB:Q6DK43 xref: UniProtKB:Q7Z465 xref: UniProtKB:Q8TCY7 xref: UniProtKB:Q8WYG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013502 ! BNIPL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0041710 name: B1AHR2_HUMAN def: "Septin" [UniProtKB:B1AHR2] xref: EMBL:CAQ07554.1 xref: UniProtKB:B1AHR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005586 ! SEPT3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0041721 name: B0QY80_HUMAN def: "Small G protein signaling modulator 3" [UniProtKB:B0QY80] xref: EMBL:CAQ08934.1 xref: UniProtKB:B0QY80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005603 ! SGSM3_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0041728 name: RTN3_HUMAN def: "Reticulon-3" [UniProtKB:O95197] synonym: "Neuroendocrine-specific protein-like 2" EXACT [UniProtKB:O95197] synonym: "NSP-like protein II" EXACT [UniProtKB:O95197] synonym: "NSPLII" EXACT [UniProtKB:O95197] xref: EMBL:AAC99319.1 xref: EMBL:AAD20951.1 xref: EMBL:AAD26810.1 xref: EMBL:AAH00634.1 xref: EMBL:AAH10556.1 xref: EMBL:AAH11394.1 xref: EMBL:AAH22993.1 xref: EMBL:AAI00823.1 xref: EMBL:AAI00824.1 xref: EMBL:AAI05982.1 xref: EMBL:AAI05983.1 xref: EMBL:AAI18551.1 xref: EMBL:AAI18629.1 xref: EMBL:AAR02474.1 xref: EMBL:AAU81930.1 xref: EMBL:BAD93008.1 xref: EMBL:BAD96618.1 xref: EMBL:DAA01931.1 xref: EMBL:DAA01941.1 xref: EMBL:DAA01943.1 xref: UniProtKB:O95197 xref: UniProtKB:Q147U9 xref: UniProtKB:Q496K2 xref: UniProtKB:Q53GN3 xref: UniProtKB:Q59EP0 xref: UniProtKB:Q5UEP2 xref: UniProtKB:Q6T930 xref: UniProtKB:Q7RTM7 xref: UniProtKB:Q7RTM8 xref: UniProtKB:Q7RTN3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013630 ! RTN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015367 ! rtn3-rtn4 physical interaction relationship: participates_in CCO:I0015559 ! rab33a-rtn3 physical interaction relationship: transforms_into CCO:B0043362 ! RTN3_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0043363 ! RTN3_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 [Term] id: CCO:B0041735 name: RTN4_HUMAN def: "Reticulon-4" [UniProtKB:Q9NQC3] synonym: "Foocen" EXACT [UniProtKB:Q9NQC3] synonym: "Neurite outgrowth inhibitor" EXACT [UniProtKB:Q9NQC3] synonym: "Neuroendocrine-specific protein" EXACT [UniProtKB:Q9NQC3] synonym: "Neuroendocrine-specific protein C homolog" EXACT [UniProtKB:Q9NQC3] synonym: "Nogo protein" EXACT [UniProtKB:Q9NQC3] synonym: "NSP" EXACT [UniProtKB:Q9NQC3] synonym: "Reticulon-5" EXACT [UniProtKB:Q9NQC3] synonym: "RTN-x" EXACT [UniProtKB:Q9NQC3] xref: EMBL:AAD27783.1 xref: EMBL:AAD31021.1 xref: EMBL:AAD31022.1 xref: EMBL:AAD39920.1 xref: EMBL:AAG12176.1 xref: EMBL:AAG12177.1 xref: EMBL:AAG12205.1 xref: EMBL:AAG17976.1 xref: EMBL:AAG40878.1 xref: EMBL:AAG43160.1 xref: EMBL:AAH01035.1 xref: EMBL:AAH07109.1 xref: EMBL:AAH10737.1 xref: EMBL:AAH12619.1 xref: EMBL:AAH14366.1 xref: EMBL:AAH26788.1 xref: EMBL:AAH68991.1 xref: EMBL:AAI50183.1 xref: EMBL:AAI52426.1 xref: EMBL:AAI52556.1 xref: EMBL:AAK20831.1 xref: EMBL:AAM64243.1 xref: EMBL:AAM64248.1 xref: EMBL:BAA74909.2 xref: EMBL:BAA83712.1 xref: EMBL:BAB18927.1 xref: EMBL:BAB18928.1 xref: EMBL:CAB99248.1 xref: EMBL:CAB99249.1 xref: EMBL:CAB99250.1 xref: EMBL:EAX00116.1 xref: UniProtKB:O94962 xref: UniProtKB:Q7L7Q8 xref: UniProtKB:Q9BXG5 xref: UniProtKB:Q9H212 xref: UniProtKB:Q9H3I3 xref: UniProtKB:Q9NQC3 xref: UniProtKB:Q9UQ42 xref: UniProtKB:Q9Y293 xref: UniProtKB:Q9Y2Y7 xref: UniProtKB:Q9Y5U6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013631 ! RTN4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015104 ! lrch4-rtn4 physical interaction relationship: participates_in CCO:I0015198 ! plekhf2-rtn4 physical interaction relationship: participates_in CCO:I0015367 ! rtn3-rtn4 physical interaction relationship: participates_in CCO:I0015514 ! napa-rtn4 physical interaction relationship: participates_in CCO:I0015602 ! rtn4-spg21 physical interaction relationship: participates_in CCO:I0015768 ! rab33a-rtn4 physical interaction relationship: participates_in CCO:I0015809 ! col4a3bp-rtn4 physical interaction relationship: participates_in CCO:I0020055 ! lrpap1-rtn4 physical interaction relationship: participates_in CCO:I0020444 ! rtn4-crmp1 physical interaction relationship: participates_in CCO:P0001152 ! negative regulation of anti-apoptosis relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0001277 ! negative regulation of axon extension relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0043365 ! RTN4_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0043366 ! RTN4_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0043367 ! RTN4_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0043368 ! RTN4_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0043369 ! RTN4_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0043370 ! RTN4_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0043371 ! RTN4_HUMAN-Phosphothreonine188 relationship: transforms_into CCO:B0043372 ! RTN4_HUMAN-Phosphoserine446 relationship: transforms_into CCO:B0043373 ! RTN4_HUMAN-Phosphoserine860 relationship: transforms_into CCO:B0043374 ! RTN4_HUMAN-Phosphoserine863 relationship: transforms_into CCO:B0043375 ! RTN4_HUMAN-Phosphoserine881 relationship: transforms_into CCO:B0043376 ! RTN4_HUMAN-Phosphotyrosine889 relationship: transforms_into CCO:B0070261 ! RTN4_HUMAN-Phosphoserine181 [Term] id: CCO:B0041769 name: APOL3_HUMAN def: "Apolipoprotein L3" [UniProtKB:O95236] synonym: "ApoL-III" EXACT [UniProtKB:O95236] synonym: "Apolipoprotein L-III" EXACT [UniProtKB:O95236] synonym: "CG12_1" EXACT [UniProtKB:O95236] synonym: "TNF-inducible protein CG12-1" EXACT [UniProtKB:O95236] xref: EMBL:AAC83233.1 xref: EMBL:AAG50344.1 xref: EMBL:AAG50345.1 xref: EMBL:AAG50346.1 xref: EMBL:AAG50347.1 xref: EMBL:AAG50348.1 xref: EMBL:AAG50349.1 xref: EMBL:AAK20213.1 xref: EMBL:AAK26527.1 xref: EMBL:AAK26528.1 xref: EMBL:AAK26529.1 xref: EMBL:CAG30265.1 xref: EMBL:CAQ08519.1 xref: UniProtKB:B1AHI5 xref: UniProtKB:O95236 xref: UniProtKB:Q9BQ82 xref: UniProtKB:Q9BQA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013486 ! APOL3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0041800 name: CAN1_HUMAN def: "Calpain-1 catalytic subunit" [UniProtKB:P07384] synonym: "Calcium-activated neutral proteinase 1" EXACT [UniProtKB:P07384] synonym: "Calpain mu-type" EXACT [UniProtKB:P07384] synonym: "Calpain-1 large subunit" EXACT [UniProtKB:P07384] synonym: "CANP 1" EXACT [UniProtKB:P07384] synonym: "EC 3.4.22.52" EXACT [UniProtKB:P07384] synonym: "Micromolar-calpain" EXACT [UniProtKB:P07384] synonym: "muCANP" EXACT [UniProtKB:P07384] xref: EMBL:AAH08751.1 xref: EMBL:AAH17200.1 xref: EMBL:AAV41878.1 xref: EMBL:CAA27881.1 xref: UniProtKB:P07384 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013509 ! CAPN1_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000667 ! calcium-dependent cysteine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0041821 name: CAN2_HUMAN def: "Calpain-2 catalytic subunit precursor" [UniProtKB:P17655] synonym: "Calcium-activated neutral proteinase 2" EXACT [UniProtKB:P17655] synonym: "Calpain large polypeptide L2" EXACT [UniProtKB:P17655] synonym: "Calpain M-type" EXACT [UniProtKB:P17655] synonym: "Calpain-2 large subunit" EXACT [UniProtKB:P17655] synonym: "CANP 2" EXACT [UniProtKB:P17655] synonym: "EC 3.4.22.53" EXACT [UniProtKB:P17655] synonym: "M-calpain" EXACT [UniProtKB:P17655] synonym: "Millimolar-calpain" EXACT [UniProtKB:P17655] xref: EMBL:AAA35645.1 xref: EMBL:AAA52760.1 xref: EMBL:AAF99682.1 xref: EMBL:AAH07686.1 xref: EMBL:AAH11828.1 xref: EMBL:AAH21303.1 xref: EMBL:AAV80421.1 xref: UniProtKB:P17655 xref: UniProtKB:Q16738 xref: UniProtKB:Q6PJT3 xref: UniProtKB:Q8WU26 xref: UniProtKB:Q9HBB1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013510 ! CAPN2_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000667 ! calcium-dependent cysteine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0018743 ! capn2-capns1-1 direct interaction relationship: participates_in CCO:I0018744 ! capn2-capns1-2 direct interaction [Term] id: CCO:B0041822 name: CAN5_HUMAN def: "Calpain-5" [UniProtKB:O15484] synonym: "EC 3.4.22.-" EXACT [UniProtKB:O15484] synonym: "htra-3" EXACT [UniProtKB:O15484] synonym: "nCL-3" EXACT [UniProtKB:O15484] synonym: "New calpain 3" EXACT [UniProtKB:O15484] xref: EMBL:AAC51869.1 xref: EMBL:AAH18123.1 xref: EMBL:CAA71584.1 xref: UniProtKB:O00263 xref: UniProtKB:O15484 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013511 ! CAPN5_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000667 ! calcium-dependent cysteine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0041843 name: TYY2_HUMAN def: "Transcription factor YY2" [UniProtKB:O15391] synonym: "Yin and yang 2" EXACT [UniProtKB:O15391] synonym: "YY-2" EXACT [UniProtKB:O15391] synonym: "Zinc finger protein 631" EXACT [UniProtKB:O15391] xref: EMBL:AAD08633.1 xref: EMBL:AAS68634.1 xref: EMBL:EAW98983.1 xref: UniProtKB:O15391 xref: UniProtKB:Q6Q1S4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013031 ! YY2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0041921 name: B0UXY8_HUMAN def: "Gamma-aminobutyric acid (GABA) B receptor, 1" [UniProtKB:B0UXY8] xref: EMBL:CAQ09396.1 xref: UniProtKB:B0UXY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004680 ! GABBR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0041922 name: GABR2_HUMAN def: "Gamma-aminobutyric acid type B receptor subunit 2 precursor" [UniProtKB:O75899] synonym: "G-protein coupled receptor 51" EXACT [UniProtKB:O75899] synonym: "GABA-B receptor 2" EXACT [UniProtKB:O75899] synonym: "GABA-B-R2" EXACT [UniProtKB:O75899] synonym: "GABABR2" EXACT [UniProtKB:O75899] synonym: "Gb2" EXACT [UniProtKB:O75899] synonym: "HG20" EXACT [UniProtKB:O75899] xref: EMBL:AAC63228.1 xref: EMBL:AAC99345.1 xref: EMBL:AAD03336.1 xref: EMBL:AAD30389.1 xref: EMBL:AAD45867.1 xref: EMBL:AAH35071.2 xref: EMBL:CAA09942.1 xref: EMBL:CAD13322.2 xref: EMBL:CAH71298.1 xref: EMBL:CAH72233.1 xref: EMBL:CAI12581.1 xref: UniProtKB:O75899 xref: UniProtKB:O75974 xref: UniProtKB:O75975 xref: UniProtKB:Q5VXZ2 xref: UniProtKB:Q8WX04 xref: UniProtKB:Q9P1R2 xref: UniProtKB:Q9UNR1 xref: UniProtKB:Q9UNS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013542 ! GABBR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020014 ! gpr51-sh3gl3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000749 ! gamma-aminobutyric acid signaling pathway relationship: transforms_into CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 [Term] id: CCO:B0041924 name: Q8NHA5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHA5] xref: EMBL:BAC05730.1 xref: UniProtKB:Q8NHA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0041925 name: B0UXY7_HUMAN def: "Gamma-aminobutyric acid (GABA) B receptor, 1" [UniProtKB:B0UXY7] xref: EMBL:CAQ09395.1 xref: UniProtKB:B0UXY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004680 ! GABBR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0041927 name: A6NNW8_HUMAN def: "Putative uncharacterized protein GABBR1" [UniProtKB:A6NNW8] xref: UniProtKB:A6NNW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004680 ! GABBR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0041934 name: B1AMW7_HUMAN def: "Cell division cycle 7 homolog (S. cerevisiae)" [UniProtKB:B1AMW7] xref: EMBL:CAI14445.1 xref: UniProtKB:B1AMW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004294 ! CDC7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0041947 name: MINK1_HUMAN def: "Misshapen-like kinase 1" [UniProtKB:Q8N4C8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8N4C8] synonym: "GCK family kinase MiNK" EXACT [UniProtKB:Q8N4C8] synonym: "MAPK/ERK kinase kinase kinase 6" EXACT [UniProtKB:Q8N4C8] synonym: "MEK kinase kinase 6" EXACT [UniProtKB:Q8N4C8] synonym: "MEKKK 6" EXACT [UniProtKB:Q8N4C8] synonym: "Misshapen/NIK-related kinase" EXACT [UniProtKB:Q8N4C8] synonym: "Mitogen-activated protein kinase kinase kinase kinase 6" EXACT [UniProtKB:Q8N4C8] xref: EMBL:AAH34673.1 xref: EMBL:BAA90753.1 xref: EMBL:BAA94838.1 xref: UniProtKB:Q8N4C8 xref: UniProtKB:Q9P1X1 xref: UniProtKB:Q9P2R8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013595 ! MINK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0043329 ! MINK1_HUMAN-Phosphoserine763 relationship: transforms_into CCO:B0043330 ! MINK1_HUMAN-Phosphoserine778 relationship: transforms_into CCO:B0043331 ! MINK1_HUMAN-Phosphoserine782 relationship: transforms_into CCO:B0043332 ! MINK1_HUMAN-Phosphoserine916 relationship: transforms_into CCO:B0068187 ! MINK1_HUMAN-Phosphoserine777 [Term] id: CCO:B0041948 name: NRK_HUMAN def: "Nik-related protein kinase" [UniProtKB:Q7Z2Y5] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q7Z2Y5] xref: EMBL:AAI08703.1 xref: EMBL:BAD18683.1 xref: EMBL:CAD98108.1 xref: UniProtKB:Q32ND6 xref: UniProtKB:Q5H9K2 xref: UniProtKB:Q6ZMP2 xref: UniProtKB:Q7Z2Y5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013604 ! NRK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0041953 name: M4K4_HUMAN def: "Mitogen-activated protein kinase kinase kinase kinase 4" [UniProtKB:O95819] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O95819] synonym: "HPK/GCK-like kinase HGK" EXACT [UniProtKB:O95819] synonym: "MAPK/ERK kinase kinase kinase 4" EXACT [UniProtKB:O95819] synonym: "MEK kinase kinase 4" EXACT [UniProtKB:O95819] synonym: "MEKKK 4" EXACT [UniProtKB:O95819] synonym: "Nck-interacting kinase" EXACT [UniProtKB:O95819] xref: EMBL:AAD16137.1 xref: EMBL:AAO32626.1 xref: EMBL:BAA31662.1 xref: EMBL:BAA33714.1 xref: EMBL:CAB70907.2 xref: UniProtKB:O75172 xref: UniProtKB:O95819 xref: UniProtKB:Q9NST7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013585 ! MAP4K4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0043317 ! M4K4_HUMAN-Phosphothreonine181 relationship: transforms_into CCO:B0043318 ! M4K4_HUMAN-Phosphoserine602 relationship: transforms_into CCO:B0043319 ! M4K4_HUMAN-Phosphoserine629 relationship: transforms_into CCO:B0043320 ! M4K4_HUMAN-Phosphoserine631 relationship: transforms_into CCO:B0043321 ! M4K4_HUMAN-Phosphoserine639 relationship: transforms_into CCO:B0043322 ! M4K4_HUMAN-Phosphoserine692 relationship: transforms_into CCO:B0043323 ! M4K4_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0043324 ! M4K4_HUMAN-Phosphoserine801 relationship: transforms_into CCO:B0043325 ! M4K4_HUMAN-Phosphoserine805 relationship: transforms_into CCO:B0043326 ! M4K4_HUMAN-Phosphoserine900 [Term] id: CCO:B0041960 name: A2ABB0_HUMAN def: "Retinoid X receptor, beta" [UniProtKB:A2ABB0] xref: EMBL:CAM24943.1 xref: EMBL:CAM25785.1 xref: EMBL:CAQ09063.1 xref: EMBL:CAQ10297.1 xref: EMBL:CAQ11081.1 xref: UniProtKB:A2ABB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008140 ! RXRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0042007 name: ALR_HUMAN def: "FAD-linked sulfhydryl oxidase ALR" [UniProtKB:P55789] synonym: "Augmenter of liver regeneration" EXACT [UniProtKB:P55789] synonym: "EC 1.8.3.2" EXACT [UniProtKB:P55789] synonym: "hERV1" EXACT [UniProtKB:P55789] xref: EMBL:AAA96390.2 xref: EMBL:AAD36986.1 xref: EMBL:AAH02429.1 xref: EMBL:AAH28348.2 xref: UniProtKB:P55789 xref: UniProtKB:Q8TAH6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013478 ! GFER_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020246 ! ascc2-gfer physical interaction [Term] id: CCO:B0042018 name: APIP_HUMAN def: "APAF1-interacting protein" [UniProtKB:Q96GX9] xref: EMBL:AAD27738.1 xref: EMBL:AAH08440.1 xref: EMBL:AAH09077.1 xref: EMBL:AAH10133.1 xref: EMBL:AAH17594.1 xref: UniProtKB:Q6PJX6 xref: UniProtKB:Q8WVU2 xref: UniProtKB:Q96GX9 xref: UniProtKB:Q96HK2 xref: UniProtKB:Q9Y318 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013483 ! APIP_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015431 ! mmrp19-vps25 physical interaction relationship: participates_in CCO:I0017102 ! traf1-q96gx9 physical interaction relationship: participates_in CCO:I0017128 ! traf2-q96gx9 physical interaction [Term] id: CCO:B0042028 name: ENOPH_HUMAN def: "Enolase-phosphatase E1" [UniProtKB:Q9UHY7] synonym: "2,3-diketo-5-methylthio-1-phosphopentane phosphatase" EXACT [UniProtKB:Q9UHY7] synonym: "EC 3.1.3.77" EXACT [UniProtKB:Q9UHY7] synonym: "MASA homolog" EXACT [UniProtKB:Q9UHY7] xref: EMBL:AAF14866.1 xref: EMBL:AAH01317.1 xref: EMBL:AAH65815.1 xref: EMBL:AAQ13671.1 xref: EMBL:BAB14160.1 xref: EMBL:CAG33422.1 xref: UniProtKB:Q7Z4C5 xref: UniProtKB:Q9BVC2 xref: UniProtKB:Q9UHY7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013526 ! ENOPH1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0002300 ! phosphoglycolate phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006036 ! acireductone synthase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0020658 ! rps27-masa physical interaction [Term] id: CCO:B0042031 name: PDIA3_HUMAN def: "Protein disulfide-isomerase A3 precursor" [UniProtKB:P30101] synonym: "58 kDa glucose-regulated protein" EXACT [UniProtKB:P30101] synonym: "58 kDa microsomal protein" EXACT [UniProtKB:P30101] synonym: "Disulfide isomerase ER-60" EXACT [UniProtKB:P30101] synonym: "EC 5.3.4.1" EXACT [UniProtKB:P30101] synonym: "ERp57" EXACT [UniProtKB:P30101] synonym: "ERp60" EXACT [UniProtKB:P30101] synonym: "p58" EXACT [UniProtKB:P30101] xref: EMBL:AAC50331.1 xref: EMBL:AAC51518.1 xref: EMBL:AAH14433.1 xref: EMBL:AAH36000.4 xref: EMBL:AAH71878.1 xref: EMBL:BAA03759.1 xref: EMBL:BAA11928.1 xref: EMBL:CAA89996.1 xref: UniProtKB:P30101 xref: UniProtKB:Q13453 xref: UniProtKB:Q14255 xref: UniProtKB:Q8IYF8 xref: UniProtKB:Q9UMU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013608 ! PDIA3_human relationship: has_function CCO:F0000320 ! protein disulfide isomerase activity relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0007710 ! tap1-b2m physical interaction relationship: participates_in CCO:I0015868 ! tap1-pd1a3-2 direct interaction relationship: participates_in CCO:I0018264 ! tap1-pd1a3-1 direct interaction relationship: participates_in CCO:I0018405 ! tap1-pd1a3 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0042116 name: GDF5_HUMAN def: "Growth/differentiation factor 5 precursor" [UniProtKB:P43026] synonym: "Cartilage-derived morphogenetic protein 1" EXACT [UniProtKB:P43026] synonym: "CDMP-1" EXACT [UniProtKB:P43026] synonym: "GDF-5" EXACT [UniProtKB:P43026] synonym: "Radotermin" EXACT [UniProtKB:P43026] xref: EMBL:AAA57007.1 xref: EMBL:AAH32495.1 xref: EMBL:CAA56874.1 xref: EMBL:CAB89416.1 xref: UniProtKB:P43026 xref: UniProtKB:Q96SB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013546 ! GDF5_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0042120 name: NODAL_HUMAN def: "Nodal homolog precursor" [UniProtKB:Q96S42] xref: EMBL:AAH33585.1 xref: EMBL:AAI04977.1 xref: EMBL:AAI12026.1 xref: EMBL:BAB62524.1 xref: UniProtKB:Q2M3A5 xref: UniProtKB:Q8N4V3 xref: UniProtKB:Q96S42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013603 ! NODAL_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000527 ! repression of premature neural plate formation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001147 ! stem cell maintenance [Term] id: CCO:B0042127 name: BMP10_HUMAN def: "Bone morphogenetic protein 10 precursor" [UniProtKB:O95393] synonym: "BMP-10" EXACT [UniProtKB:O95393] xref: EMBL:AAC77462.1 xref: EMBL:AAH69080.1 xref: EMBL:AAI01735.1 xref: EMBL:AAI05064.1 xref: EMBL:AAY15075.1 xref: UniProtKB:O95393 xref: UniProtKB:Q53R17 xref: UniProtKB:Q6NTE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013496 ! BMP10_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005186 ! receptor serine/threonine kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000934 ! Z disc relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0001003 ! negative regulation of endothelial cell migration relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001714 ! activin receptor signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0003231 ! cardiac muscle cell proliferation relationship: participates_in CCO:P0003234 ! positive regulation of cardiac muscle cell proliferation [Term] id: CCO:B0042130 name: BMP6_HUMAN def: "Bone morphogenetic protein 6 precursor" [UniProtKB:P22004] synonym: "BMP-6" EXACT [UniProtKB:P22004] xref: EMBL:AAA36737.1 xref: EMBL:CAI19426.1 xref: EMBL:CAI19472.1 xref: UniProtKB:P22004 xref: UniProtKB:Q5TCP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013499 ! BMP6_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001607 ! positive regulation of aldosterone biosynthetic process relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0042178 name: MAFG_HUMAN def: "Transcription factor MafG" [UniProtKB:O15525] synonym: "hMAF" EXACT [UniProtKB:O15525] synonym: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog G" EXACT [UniProtKB:O15525] xref: EMBL:AAC14427.1 xref: EMBL:AAC51737.1 xref: EMBL:AAH12327.1 xref: EMBL:CAA72284.1 xref: UniProtKB:O15525 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013589 ! MAFG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019760 ! mafg-chd3 physical interaction relationship: participates_in CCO:I0020057 ! mafg-med31 physical interaction relationship: participates_in CCO:I0020058 ! mafg-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020059 ! mafg-vim physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002418 ! regulation of epidermal cell differentiation [Term] id: CCO:B0042180 name: MAFF_HUMAN def: "Transcription factor MafF" [UniProtKB:Q9ULX9] synonym: "U-Maf" EXACT [UniProtKB:Q9ULX9] synonym: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog F" EXACT [UniProtKB:Q9ULX9] xref: EMBL:AAH15037.1 xref: EMBL:AAH67751.1 xref: EMBL:BAA86871.1 xref: EMBL:BAA92029.1 xref: EMBL:CAB45266.1 xref: EMBL:CAB52435.1 xref: UniProtKB:Q9ULX9 xref: UniProtKB:Q9Y525 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013588 ! MAFF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020361 ! maff-psap physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002418 ! regulation of epidermal cell differentiation [Term] id: CCO:B0042181 name: B0QY71_HUMAN def: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog F (Avian)" [UniProtKB:B0QY71] xref: EMBL:CAQ08283.1 xref: UniProtKB:B0QY71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013588 ! MAFF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0042182 name: B0QY70_HUMAN def: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog F (Avian)" [UniProtKB:B0QY70] xref: EMBL:CAQ08282.1 xref: UniProtKB:B0QY70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013588 ! MAFF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0042184 name: A8WFP5_HUMAN def: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian)" [UniProtKB:A8WFP5] xref: EMBL:AAI52388.1 xref: UniProtKB:A8WFP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013590 ! MAFK_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0042185 name: MAFA_HUMAN def: "Transcription factor MafA" [UniProtKB:Q8NHW3] synonym: "Pancreatic beta-cell-specific transcriptional activator" EXACT [UniProtKB:Q8NHW3] synonym: "Transcription factor RIPE3b1" EXACT [UniProtKB:Q8NHW3] synonym: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog A" EXACT [UniProtKB:Q8NHW3] xref: EMBL:AAL89527.1 xref: EMBL:BAC20389.1 xref: UniProtKB:Q8NHW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013587 ! MAFA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0043327 ! MAFA_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0043328 ! MAFA_HUMAN-Phosphoserine65 [Term] id: CCO:B0042221 name: A8MT20_HUMAN def: "Putative uncharacterized protein GRM5" [UniProtKB:A8MT20] xref: UniProtKB:A8MT20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013555 ! GRM5_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042222 name: GRM3_HUMAN def: "Metabotropic glutamate receptor 3 precursor" [UniProtKB:Q14832] synonym: "mGluR3" EXACT [UniProtKB:Q14832] xref: EMBL:AAC60379.2 xref: EMBL:AAD15616.1 xref: EMBL:AAH22496.2 xref: EMBL:AAH41407.1 xref: EMBL:CAA54796.1 xref: UniProtKB:Q14832 xref: UniProtKB:Q75MV4 xref: UniProtKB:Q75N17 xref: UniProtKB:Q86YG6 xref: UniProtKB:Q8TBH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013553 ! GRM3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042225 name: GRM4_HUMAN def: "Metabotropic glutamate receptor 4 precursor" [UniProtKB:Q14833] synonym: "mGluR4" EXACT [UniProtKB:Q14833] xref: EMBL:AAB51762.1 xref: EMBL:CAA56784.1 xref: EMBL:CAI17348.1 xref: UniProtKB:Q14833 xref: UniProtKB:Q5SZ84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013554 ! GRM4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000734 ! metabotropic glutamate receptor, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002235 ! neuroprotection [Term] id: CCO:B0042226 name: Q8N0Z0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8N0Z0] xref: EMBL:BAC05713.1 xref: EMBL:BAC05739.1 xref: EMBL:BAC05802.1 xref: UniProtKB:Q8N0Z0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042227 name: GRM7_HUMAN def: "Metabotropic glutamate receptor 7 precursor" [UniProtKB:Q14831] synonym: "mGluR7" EXACT [UniProtKB:Q14831] xref: EMBL:AAB51763.1 xref: EMBL:AAM47557.1 xref: EMBL:AAM47558.1 xref: EMBL:AAM47559.1 xref: EMBL:CAA64245.1 xref: UniProtKB:Q14831 xref: UniProtKB:Q8NFS2 xref: UniProtKB:Q8NFS3 xref: UniProtKB:Q8NFS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013557 ! GRM7_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: located_in CCO:C0002008 ! presynaptic active zone membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0043287 ! GRM7_HUMAN-Phosphoserine900 [Term] id: CCO:B0042228 name: A4D0Y3_HUMAN def: "Glutamate receptor, metabotropic 8" [UniProtKB:A4D0Y3] xref: EMBL:EAL24322.1 xref: UniProtKB:A4D0Y3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013558 ! GRM8_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042229 name: Q8NHA9_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHA9] xref: EMBL:BAC05726.1 xref: UniProtKB:Q8NHA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042230 name: GRM5_HUMAN def: "Metabotropic glutamate receptor 5 precursor" [UniProtKB:P41594] synonym: "mGluR5" EXACT [UniProtKB:P41594] xref: EMBL:AAD13954.1 xref: EMBL:BAA05891.1 xref: EMBL:BAA05892.1 xref: UniProtKB:P41594 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013555 ! GRM5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000741 ! metabotropic glutamate receptor, phospholipase C activating pathway [Term] id: CCO:B0042232 name: Q59GK5_HUMAN def: "Glutamate receptor, metabotropic 4 variant" [UniProtKB:Q59GK5] xref: EMBL:BAD92341.1 xref: UniProtKB:Q59GK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042233 name: Q99997_HUMAN def: "Putative Metabotropic Glutamate Receptor 8" [UniProtKB:Q99997] xref: EMBL:AAB46348.1 xref: UniProtKB:Q99997 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042237 name: Q86YG3_HUMAN def: "Similar to glutamate receptor, metabotropic 2" [UniProtKB:Q86YG3] xref: EMBL:AAH41447.1 xref: UniProtKB:Q86YG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042238 name: Q6J164_HUMAN def: "Metabotropic glutamate receptor 5 splice variant d" [UniProtKB:Q6J164] xref: EMBL:AAT37960.1 xref: UniProtKB:Q6J164 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013555 ! GRM5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042239 name: GRM2_HUMAN def: "Metabotropic glutamate receptor 2 precursor" [UniProtKB:Q14416] synonym: "mGluR2" EXACT [UniProtKB:Q14416] xref: EMBL:AAA76855.1 xref: EMBL:AAI13616.1 xref: EMBL:AAI13620.1 xref: EMBL:AAY14640.1 xref: EMBL:BAB19817.1 xref: UniProtKB:Q14416 xref: UniProtKB:Q14CU5 xref: UniProtKB:Q52MC6 xref: UniProtKB:Q9H3N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013552 ! GRM2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042241 name: GRM8_HUMAN def: "Metabotropic glutamate receptor 8 precursor" [UniProtKB:O00222] synonym: "mGluR8" EXACT [UniProtKB:O00222] xref: EMBL:AAB51764.1 xref: EMBL:AAB72040.1 xref: EMBL:AAH93725.1 xref: EMBL:AAI01676.1 xref: EMBL:AAT37959.1 xref: EMBL:CAB36968.1 xref: EMBL:CAB36969.1 xref: UniProtKB:O00222 xref: UniProtKB:O15493 xref: UniProtKB:O95945 xref: UniProtKB:O95946 xref: UniProtKB:Q3MIV9 xref: UniProtKB:Q52M02 xref: UniProtKB:Q6J165 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013558 ! GRM8_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001311 ! negative regulation of cAMP biosynthetic process [Term] id: CCO:B0042244 name: GRM6_HUMAN def: "Metabotropic glutamate receptor 6 precursor" [UniProtKB:O15303] synonym: "mGluR6" EXACT [UniProtKB:O15303] xref: EMBL:AAB82068.1 xref: UniProtKB:O15303 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013556 ! GRM6_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000751 ! metabotropic glutamate receptor signaling pathway [Term] id: CCO:B0042245 name: GRM1_HUMAN def: "Metabotropic glutamate receptor 1 precursor" [UniProtKB:Q13255] synonym: "mGluR1" EXACT [UniProtKB:Q13255] xref: EMBL:AAA87843.1 xref: EMBL:AAA87844.1 xref: EMBL:AAB05337.1 xref: EMBL:AAB05338.1 xref: EMBL:CAH71181.1 xref: EMBL:CAH71182.1 xref: EMBL:CAI20335.1 xref: EMBL:CAI20336.1 xref: EMBL:CAI22468.1 xref: EMBL:CAI22469.1 xref: UniProtKB:Q13255 xref: UniProtKB:Q13256 xref: UniProtKB:Q14757 xref: UniProtKB:Q14758 xref: UniProtKB:Q5VTF7 xref: UniProtKB:Q5VTF8 xref: UniProtKB:Q9NU10 xref: UniProtKB:Q9UGS9 xref: UniProtKB:Q9UGT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013551 ! GRM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0043286 ! GRM1_HUMAN-Phosphotyrosine672 relationship: transforms_into CCO:B0066627 ! GRM1_HUMAN-Phosphotyrosine1109 relationship: transforms_into CCO:B0066628 ! GRM1_HUMAN-Phosphotyrosine1111 [Term] id: CCO:B0042246 name: A8K1R9_HUMAN def: "cDNA FLJ78161, highly similar to Homo sapiens glutamate receptor, metabotropic 2 (GRM2), mRNA" [UniProtKB:A8K1R9] xref: EMBL:BAF82673.1 xref: UniProtKB:A8K1R9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042247 name: Q2PNZ6_HUMAN def: "Metabotropic glutamate receptor 3 splice variant" [UniProtKB:Q2PNZ6] xref: EMBL:ABC47402.1 xref: UniProtKB:Q2PNZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013553 ! GRM3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042251 name: Q6ZMQ2_HUMAN def: "cDNA FLJ16766 fis, clone BRAWH3013197, highly similar to Metabotropic glutamate receptor 4" [UniProtKB:Q6ZMQ2] xref: EMBL:BAD18673.1 xref: UniProtKB:Q6ZMQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042255 name: Q59HC2_HUMAN def: "Glutamate receptor, metabotropic 1 variant" [UniProtKB:Q59HC2] xref: EMBL:BAD92074.1 xref: UniProtKB:Q59HC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0042283 name: IMPA2_HUMAN def: "Inositol monophosphatase 2" [UniProtKB:O14732] synonym: "EC 3.1.3.25" EXACT [UniProtKB:O14732] synonym: "IMP 2" EXACT [UniProtKB:O14732] synonym: "IMPase 2" EXACT [UniProtKB:O14732] synonym: "Inositol-1(or 4)-monophosphatase 2" EXACT [UniProtKB:O14732] synonym: "Myo-inositol monophosphatase A2" EXACT [UniProtKB:O14732] xref: EMBL:AAB70915.1 xref: EMBL:AAD40683.1 xref: EMBL:AAF07824.1 xref: EMBL:AAH17176.1 xref: EMBL:AAP35710.1 xref: UniProtKB:O14732 xref: UniProtKB:Q9UJT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013567 ! IMPA2_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0002270 ! inositol-1(or 4)-monophosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020570 ! herpud1-impa2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0042291 name: IMPA1_HUMAN def: "Inositol monophosphatase" [UniProtKB:P29218] synonym: "EC 3.1.3.25" EXACT [UniProtKB:P29218] synonym: "IMP" EXACT [UniProtKB:P29218] synonym: "IMPase" EXACT [UniProtKB:P29218] synonym: "Inositol-1(or 4)-monophosphatase" EXACT [UniProtKB:P29218] synonym: "Lithium-sensitive myo-inositol monophosphatase A1" EXACT [UniProtKB:P29218] xref: EMBL:AAB97468.1 xref: EMBL:AAD52997.1 xref: EMBL:AAH08381.1 xref: EMBL:AAH09565.1 xref: EMBL:CAA47359.1 xref: EMBL:CAA72195.1 xref: UniProtKB:P29218 xref: UniProtKB:Q9UK71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013566 ! IMPA1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0002270 ! inositol-1(or 4)-monophosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004657 ! lithium ion binding relationship: has_function CCO:F0005685 ! phosphoric ester hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015849 ! impa1-impa1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0042293 name: ACHG_HUMAN def: "Acetylcholine receptor subunit gamma precursor" [UniProtKB:P07510] xref: EMBL:AAY24103.1 xref: EMBL:CAA25861.1 xref: UniProtKB:P07510 xref: UniProtKB:Q53RG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013474 ! CHRNG_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002725 ! channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043185 ! ACHG_HUMAN-Phosphothreonine285 [Term] id: CCO:B0042294 name: ACHE_HUMAN def: "Acetylcholine receptor subunit epsilon precursor" [UniProtKB:Q04844] xref: EMBL:AAD24503.1 xref: EMBL:CAA47030.1 xref: UniProtKB:Q04844 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013473 ! CHRNE_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001835 ! cation transmembrane transporter activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0042401 name: B0V0L9_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:B0V0L9] xref: EMBL:CAQ07247.1 xref: UniProtKB:B0V0L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0042404 name: B0UXD5_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:B0UXD5] xref: EMBL:CAQ07028.1 xref: UniProtKB:B0UXD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0042408 name: HIF3A_HUMAN def: "Hypoxia-inducible factor 3 alpha" [UniProtKB:Q9Y2N7] synonym: "Basic-helix-loop-helix-PAS protein MOP7" EXACT [UniProtKB:Q9Y2N7] synonym: "HIF-3 alpha" EXACT [UniProtKB:Q9Y2N7] synonym: "HIF3 alpha 1" EXACT [UniProtKB:Q9Y2N7] synonym: "Inhibitory PAS domain protein" EXACT [UniProtKB:Q9Y2N7] synonym: "IPAS" EXACT [UniProtKB:Q9Y2N7] synonym: "Member of PAS protein 7" EXACT [UniProtKB:Q9Y2N7] xref: EMBL:AAD22668.1 xref: EMBL:AAH80551.1 xref: EMBL:AAL69947.1 xref: EMBL:BAB13865.1 xref: EMBL:BAB14824.1 xref: EMBL:BAB55324.1 xref: EMBL:BAB69689.1 xref: EMBL:BAD93355.1 xref: UniProtKB:Q58A43 xref: UniProtKB:Q66K72 xref: UniProtKB:Q8WXA1 xref: UniProtKB:Q96K34 xref: UniProtKB:Q9H7Z9 xref: UniProtKB:Q9HAI2 xref: UniProtKB:Q9Y2N7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013563 ! HIF3A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0043289 ! HIF3A_HUMAN-4-hydroxyproline492 [Term] id: CCO:B0042415 name: A8MYV6_HUMAN def: "Putative uncharacterized protein HIF1A (Hypoxia-inducible factor 1, alpha subunit (Basic helix-loop-helix transcription factor), isoform CRA_a)" [UniProtKB:A8MYV6] xref: EMBL:EAW80806.1 xref: UniProtKB:A8MYV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004806 ! HIF1A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0042416 name: A8MPQ1_HUMAN def: "Putative uncharacterized protein HIF3A" [UniProtKB:A8MPQ1] xref: UniProtKB:A8MPQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013563 ! HIF3A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0042506 name: DESP_HUMAN def: "Desmoplakin" [UniProtKB:P15924] synonym: "250/210 kDa paraneoplastic pemphigus antigen" EXACT [UniProtKB:P15924] synonym: "DP" EXACT [UniProtKB:P15924] xref: EMBL:AAA35766.1 xref: EMBL:AAA85135.1 xref: EMBL:AAF19785.1 xref: EMBL:CAA19927.1 xref: UniProtKB:O75993 xref: UniProtKB:P15924 xref: UniProtKB:Q14189 xref: UniProtKB:Q9UHN4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013521 ! DSP_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000170 ! cornified envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0016416 ! nfkbib-dsp physical interaction relationship: participates_in CCO:I0016482 ! ikbke-dsp physical interaction relationship: participates_in CCO:I0016884 ! relb-dsp physical interaction relationship: transforms_into CCO:B0043241 ! DESP_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0043242 ! DESP_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0043243 ! DESP_HUMAN-Phosphothreonine1220 relationship: transforms_into CCO:B0043244 ! DESP_HUMAN-Phosphoserine1225 relationship: transforms_into CCO:B0043245 ! DESP_HUMAN-Phosphoserine2024 relationship: transforms_into CCO:B0043246 ! DESP_HUMAN-Phosphoserine2209 relationship: transforms_into CCO:B0043247 ! DESP_HUMAN-Phosphoserine2815 relationship: transforms_into CCO:B0043248 ! DESP_HUMAN-Phosphoserine2820 relationship: transforms_into CCO:B0043249 ! DESP_HUMAN-Phosphoserine2821 relationship: transforms_into CCO:B0043250 ! DESP_HUMAN-Phosphoserine2825 relationship: transforms_into CCO:B0043251 ! DESP_HUMAN-Phosphoserine2849 relationship: transforms_into CCO:B0065943 ! DESP_HUMAN-Phosphotyrosine28 relationship: transforms_into CCO:B0065944 ! DESP_HUMAN-Phosphotyrosine56 relationship: transforms_into CCO:B0065945 ! DESP_HUMAN-Phosphotyrosine2275 [Term] id: CCO:B0042518 name: BRCC3_HUMAN def: "BRCA1/BRCA2-containing complex subunit 3" [UniProtKB:P46736] xref: EMBL:AAB29005.2 xref: EMBL:AAH02999.1 xref: EMBL:AAH06540.1 xref: EMBL:CAA45917.1 xref: UniProtKB:P46736 xref: UniProtKB:Q16107 xref: UniProtKB:Q9BTZ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013504 ! BRCC3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000027 ! nuclear ubiquitin ligase complex relationship: participates_in CCO:I0015587 ! c6_1a-snapc5 physical interaction [Term] id: CCO:B0042545 name: B1AL79_HUMAN def: "Protein kinase N2 (Protein kinase N2, isoform CRA_b)" [UniProtKB:B1AL79] xref: EMBL:CAI23272.1 xref: EMBL:EAW73162.1 xref: UniProtKB:B1AL79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007981 ! PKN2_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0042581 name: B1AMV0_HUMAN def: "Ral GEF with PH domain and SH3 binding motif 2" [UniProtKB:B1AMV0] xref: EMBL:CAI21922.1 xref: UniProtKB:B1AMV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011653 ! RALGPS2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0042582 name: B1AMV1_HUMAN def: "Ral GEF with PH domain and SH3 binding motif 2" [UniProtKB:B1AMV1] xref: EMBL:CAI21923.1 xref: UniProtKB:B1AMV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011653 ! RALGPS2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0042583 name: B1AMV2_HUMAN def: "Ral GEF with PH domain and SH3 binding motif 2" [UniProtKB:B1AMV2] xref: EMBL:CAI21924.1 xref: UniProtKB:B1AMV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011653 ! RALGPS2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0042773 name: B0ZBF1_HUMAN def: "Natriuretic peptide receptor A/guanylate cyclase A (Atrionatriuretic peptide receptor A) variant 2 (Natriuretic peptide receptor A/guanylate cyclase A) (Atrionatriuretic peptide receptor A)" [UniProtKB:B0ZBF1] xref: EMBL:ACA05919.1 xref: EMBL:CAI13614.1 xref: UniProtKB:B0ZBF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007249 ! NPR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0042813 name: IL2RB_HUMAN def: "Interleukin-2 receptor subunit beta precursor" [UniProtKB:P14784] synonym: "CD122 antigen" EXACT [UniProtKB:P14784] synonym: "High affinity IL-2 receptor subunit beta" EXACT [UniProtKB:P14784] synonym: "IL-2 receptor" EXACT [UniProtKB:P14784] synonym: "P70-75" EXACT [UniProtKB:P14784] synonym: "p75" EXACT [UniProtKB:P14784] xref: EMBL:AAA59143.1 xref: EMBL:AAH25691.1 xref: EMBL:AAM54040.1 xref: EMBL:CAA18444.1 xref: EMBL:CAG30392.1 xref: UniProtKB:P14784 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013565 ! IL2RB_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001258 ! interleukin-2 receptor activity relationship: has_function CCO:F0004240 ! interleukin-2 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression [Term] id: CCO:B0042816 name: T2H2L_HUMAN def: "General transcription factor IIH subunit 2-like protein" [UniProtKB:Q6P1K8] synonym: "General transcription factor IIH polypeptide 2-like protein" EXACT [UniProtKB:Q6P1K8] xref: EMBL:AAH64557.1 xref: EMBL:AAH65021.1 xref: EMBL:AAI05981.1 xref: EMBL:BAF85050.1 xref: UniProtKB:A6NED9 xref: UniProtKB:A8K8J6 xref: UniProtKB:Q6P1K8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0042824 name: FCGR1_HUMAN def: "High affinity immunoglobulin gamma Fc receptor I precursor" [UniProtKB:P12314] synonym: "CD64 antigen" EXACT [UniProtKB:P12314] synonym: "Fc-gamma RI" EXACT [UniProtKB:P12314] synonym: "FcRI" EXACT [UniProtKB:P12314] synonym: "IgG Fc receptor I" EXACT [UniProtKB:P12314] xref: EMBL:AAA36049.1 xref: EMBL:AAA58414.1 xref: EMBL:CAA32536.1 xref: EMBL:CAA32537.1 xref: UniProtKB:P12314 xref: UniProtKB:P12315 xref: UniProtKB:Q92495 xref: UniProtKB:Q92663 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013535 ! FCGR1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066151 ! FCGR1_HUMAN-Phosphotyrosine133 relationship: transforms_into CCO:B0066152 ! FCGR1_HUMAN-Phosphotyrosine138 [Term] id: CCO:B0042830 name: FCERA_HUMAN def: "High affinity immunoglobulin epsilon receptor subunit alpha precursor" [UniProtKB:P12319] synonym: "Fc-epsilon RI-alpha" EXACT [UniProtKB:P12319] synonym: "FcERI" EXACT [UniProtKB:P12319] synonym: "IgE Fc receptor subunit alpha" EXACT [UniProtKB:P12319] xref: EMBL:AAA36204.1 xref: EMBL:AAH05912.1 xref: EMBL:CAA01564.1 xref: EMBL:CAA30025.1 xref: UniProtKB:P12319 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013532 ! FCER1A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0004152 ! IgE receptor activity relationship: has_function CCO:F0004196 ! IgE binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0002182 ! positive regulation of mast cell degranulation relationship: participates_in CCO:P0002342 ! positive regulation of interleukin-3 biosynthetic process relationship: participates_in CCO:P0002366 ! positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling [Term] id: CCO:B0042847 name: AF17_HUMAN def: "Protein AF-17" [UniProtKB:P55198] xref: EMBL:AAA21145.1 xref: EMBL:AAH07237.1 xref: EMBL:BAB15670.1 xref: EMBL:BAD92870.1 xref: EMBL:CAB63772.2 xref: UniProtKB:P55198 xref: UniProtKB:Q59F28 xref: UniProtKB:Q96IU3 xref: UniProtKB:Q9H5F6 xref: UniProtKB:Q9UF49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013477 ! MLLT6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016157 ! mllt6-ubqln4 physical interaction relationship: participates_in CCO:I0017534 ! mllt6-ubqln4-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0043188 ! AF17_HUMAN-Phosphoserine378 [Term] id: CCO:B0042870 name: EF1A2_HUMAN def: "Elongation factor 1-alpha 2" [UniProtKB:Q05639] synonym: "eEF1A-2" EXACT [UniProtKB:Q05639] synonym: "EF-1-alpha-2" EXACT [UniProtKB:Q05639] synonym: "Elongation factor 1 A-2" EXACT [UniProtKB:Q05639] synonym: "Statin S1" EXACT [UniProtKB:Q05639] xref: EMBL:AAA91835.1 xref: EMBL:AAF80488.1 xref: EMBL:AAH00432.1 xref: EMBL:AAI10410.1 xref: EMBL:CAA50280.1 xref: EMBL:CAC15522.1 xref: UniProtKB:P54266 xref: UniProtKB:Q05639 xref: UniProtKB:Q0VGC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013525 ! EEF1A2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016343 ! map3k8-eef1a2 physical interaction relationship: participates_in CCO:I0016435 ! chuk-eef1a2 physical interaction relationship: participates_in CCO:I0016515 ! ikbkg-eef1a2 physical interaction relationship: participates_in CCO:I0016607 ! map3k1-eef1a2 physical interaction relationship: participates_in CCO:I0016694 ! map3k3-eef1a2 physical interaction relationship: participates_in CCO:I0016795 ! nfkb2-eef1a2-1 physical interaction relationship: participates_in CCO:I0016945 ! q9nyj8-eef1a2 physical interaction relationship: participates_in CCO:I0017041 ! tnfrsf1b-eef1a2 physical interaction relationship: participates_in CCO:I0017067 ! tradd-eef1a2 physical interaction relationship: participates_in CCO:I0017121 ! traf2-eef1a2 physical interaction relationship: participates_in CCO:I0017140 ! traf6-eef1a2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0043257 ! EF1A2_HUMAN-Phosphotyrosine29 relationship: transforms_into CCO:B0043258 ! EF1A2_HUMAN-N6,N6,N6-trimethyllysine55 relationship: transforms_into CCO:B0043259 ! EF1A2_HUMAN-Phosphotyrosine141 relationship: transforms_into CCO:B0043260 ! EF1A2_HUMAN-N6,N6,N6-trimethyllysine165 [Term] id: CCO:B0043185 name: ACHG_HUMAN-Phosphothreonine285 def: "Protein ACHG_HUMAN with the residue 285 substituted with Phosphothreonine" [UniProtKB:P07510] xref: UniProtKB:P07510 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042293 ! ACHG_HUMAN [Term] id: CCO:B0043186 name: ACTG_HUMAN-Phosphothreonine318 def: "Protein ACTG_HUMAN with the residue 318 substituted with Phosphothreonine" [UniProtKB:P63261] xref: UniProtKB:P63261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:B0043188 name: AF17_HUMAN-Phosphoserine378 def: "Protein AF17_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:P55198] xref: UniProtKB:P55198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0042847 ! AF17_HUMAN [Term] id: CCO:B0043190 name: ANK1_HUMAN-Phosphoserine856 def: "Protein ANK1_HUMAN with the residue 856 substituted with Phosphoserine" [UniProtKB:P16157] comment: By similarity xref: UniProtKB:P16157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041523 ! ANK1_HUMAN [Term] id: CCO:B0043191 name: ANK1_HUMAN-Phosphotyrosine1073 def: "Protein ANK1_HUMAN with the residue 1073 substituted with Phosphotyrosine" [UniProtKB:P16157] comment: By similarity xref: UniProtKB:P16157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041523 ! ANK1_HUMAN [Term] id: CCO:B0043192 name: ANK1_HUMAN-Phosphothreonine1684 def: "Protein ANK1_HUMAN with the residue 1684 substituted with Phosphothreonine" [UniProtKB:P16157] xref: UniProtKB:P16157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041523 ! ANK1_HUMAN [Term] id: CCO:B0043193 name: ANK1_HUMAN-Phosphoserine1686 def: "Protein ANK1_HUMAN with the residue 1686 substituted with Phosphoserine" [UniProtKB:P16157] xref: UniProtKB:P16157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041523 ! ANK1_HUMAN [Term] id: CCO:B0043194 name: ANK2_HUMAN-Phosphoserine911 def: "Protein ANK2_HUMAN with the residue 911 substituted with Phosphoserine" [UniProtKB:Q01484] xref: UniProtKB:Q01484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041516 ! ANK2_HUMAN [Term] id: CCO:B0043195 name: ANK2_HUMAN-Phosphoserine1475 def: "Protein ANK2_HUMAN with the residue 1475 substituted with Phosphoserine" [UniProtKB:Q01484] xref: UniProtKB:Q01484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0041516 ! ANK2_HUMAN [Term] id: CCO:B0043196 name: ANK2_HUMAN-Phosphothreonine1490 def: "Protein ANK2_HUMAN with the residue 1490 substituted with Phosphothreonine" [UniProtKB:Q01484] xref: UniProtKB:Q01484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041516 ! ANK2_HUMAN [Term] id: CCO:B0043197 name: ANK2_HUMAN-Phosphothreonine2550 def: "Protein ANK2_HUMAN with the residue 2550 substituted with Phosphothreonine" [UniProtKB:Q01484] xref: UniProtKB:Q01484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041516 ! ANK2_HUMAN [Term] id: CCO:B0043198 name: ANK3_HUMAN-Phosphoserine4298 def: "Protein ANK3_HUMAN with the residue 4298 substituted with Phosphoserine" [UniProtKB:Q12955] xref: UniProtKB:Q12955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041526 ! ANK3_HUMAN [Term] id: CCO:B0043213 name: BNIP2_HUMAN-Phosphoserine114 def: "Protein BNIP2_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q12982] xref: UniProtKB:Q12982 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0002129 ! intracellular membrane-bounded organelle relationship: transformation_of CCO:B0005677 ! BNIP2_HUMAN [Term] id: CCO:B0043214 name: BNIP2_HUMAN-Phosphothreonine116 def: "Protein BNIP2_HUMAN with the residue 116 substituted with Phosphothreonine" [UniProtKB:Q12982] xref: UniProtKB:Q12982 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005677 ! BNIP2_HUMAN [Term] id: CCO:B0043225 name: CCNL1_HUMAN-Phosphoserine352 def: "Protein CCNL1_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q9UK58] xref: UniProtKB:Q9UK58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002218 ! CCNL1_HUMAN [Term] id: CCO:B0043234 name: CNOT1_HUMAN-Phosphotyrosine1933 def: "Protein CNOT1_HUMAN with the residue 1933 substituted with Phosphotyrosine" [UniProtKB:A5YKK6] xref: UniProtKB:A5YKK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032072 ! CNOT1_HUMAN [Term] id: CCO:B0043235 name: COF2_HUMAN-N-acetylalanine2 def: "Protein COF2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y281] xref: UniProtKB:Q9Y281 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033309 ! COF2_HUMAN [Term] id: CCO:B0043236 name: COPA_HUMAN-Phosphoserine1035 def: "Protein COPA_HUMAN with the residue 1035 substituted with Phosphoserine" [UniProtKB:P53621] comment: By similarity xref: UniProtKB:P53621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038202 ! COPA_HUMAN [Term] id: CCO:B0043241 name: DESP_HUMAN-Phosphoserine22 def: "Protein DESP_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043242 name: DESP_HUMAN-Phosphoserine176 def: "Protein DESP_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043243 name: DESP_HUMAN-Phosphothreonine1220 def: "Protein DESP_HUMAN with the residue 1220 substituted with Phosphothreonine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043244 name: DESP_HUMAN-Phosphoserine1225 def: "Protein DESP_HUMAN with the residue 1225 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043245 name: DESP_HUMAN-Phosphoserine2024 def: "Protein DESP_HUMAN with the residue 2024 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043246 name: DESP_HUMAN-Phosphoserine2209 def: "Protein DESP_HUMAN with the residue 2209 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043247 name: DESP_HUMAN-Phosphoserine2815 def: "Protein DESP_HUMAN with the residue 2815 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043248 name: DESP_HUMAN-Phosphoserine2820 def: "Protein DESP_HUMAN with the residue 2820 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043249 name: DESP_HUMAN-Phosphoserine2821 def: "Protein DESP_HUMAN with the residue 2821 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043250 name: DESP_HUMAN-Phosphoserine2825 def: "Protein DESP_HUMAN with the residue 2825 substituted with Phosphoserine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043251 name: DESP_HUMAN-Phosphoserine2849 def: "Protein DESP_HUMAN with the residue 2849 substituted with Phosphoserine" [UniProtKB:P15924] comment: by PKA; Potential xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0043253 name: DYN1_HUMAN-Nitrated tyrosine125 def: "Protein DYN1_HUMAN with the residue 125 substituted with Nitrated tyrosine" [UniProtKB:Q05193] comment: By similarity xref: UniProtKB:Q05193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:B0043254 name: DYN1_HUMAN-Phosphoserine774 def: "Protein DYN1_HUMAN with the residue 774 substituted with Phosphoserine" [UniProtKB:Q05193] xref: UniProtKB:Q05193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:B0043255 name: DYN1_HUMAN-Phosphothreonine776 def: "Protein DYN1_HUMAN with the residue 776 substituted with Phosphothreonine" [UniProtKB:Q05193] xref: UniProtKB:Q05193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:B0043256 name: DYN1_HUMAN-Phosphoserine778 def: "Protein DYN1_HUMAN with the residue 778 substituted with Phosphoserine" [UniProtKB:Q05193] xref: UniProtKB:Q05193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:B0043257 name: EF1A2_HUMAN-Phosphotyrosine29 def: "Protein EF1A2_HUMAN with the residue 29 substituted with Phosphotyrosine" [UniProtKB:Q05639] xref: UniProtKB:Q05639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:B0043258 name: EF1A2_HUMAN-N6,N6,N6-trimethyllysine55 def: "Protein EF1A2_HUMAN with the residue 55 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:Q05639] comment: By similarity xref: UniProtKB:Q05639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:B0043259 name: EF1A2_HUMAN-Phosphotyrosine141 def: "Protein EF1A2_HUMAN with the residue 141 substituted with Phosphotyrosine" [UniProtKB:Q05639] xref: UniProtKB:Q05639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:B0043260 name: EF1A2_HUMAN-N6,N6,N6-trimethyllysine165 def: "Protein EF1A2_HUMAN with the residue 165 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:Q05639] comment: By similarity xref: UniProtKB:Q05639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000419 ! eukaryotic translation elongation factor 1 complex relationship: transformation_of CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:B0043264 name: FLNA_HUMAN-N-acetylserine2 def: "Protein FLNA_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043265 name: FLNA_HUMAN-Phosphotyrosine1047 def: "Protein FLNA_HUMAN with the residue 1047 substituted with Phosphotyrosine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043266 name: FLNA_HUMAN-Phosphoserine1084 def: "Protein FLNA_HUMAN with the residue 1084 substituted with Phosphoserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043267 name: FLNA_HUMAN-Phosphothreonine1089 def: "Protein FLNA_HUMAN with the residue 1089 substituted with Phosphothreonine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043268 name: FLNA_HUMAN-Phosphothreonine1286 def: "Protein FLNA_HUMAN with the residue 1286 substituted with Phosphothreonine" [UniProtKB:P21333] comment: By similarity xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043269 name: FLNA_HUMAN-Phosphoserine1459 def: "Protein FLNA_HUMAN with the residue 1459 substituted with Phosphoserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043270 name: FLNA_HUMAN-Phosphoserine1533 def: "Protein FLNA_HUMAN with the residue 1533 substituted with Phosphoserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043271 name: FLNA_HUMAN-Phosphoserine2152 def: "Protein FLNA_HUMAN with the residue 2152 substituted with Phosphoserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043272 name: FLNA_HUMAN-Phosphoserine2158 def: "Protein FLNA_HUMAN with the residue 2158 substituted with Phosphoserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043273 name: FLNA_HUMAN-Phosphoserine2284 def: "Protein FLNA_HUMAN with the residue 2284 substituted with Phosphoserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043274 name: FLNA_HUMAN-Phosphoserine2327 def: "Protein FLNA_HUMAN with the residue 2327 substituted with Phosphoserine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0043275 name: FLNB_HUMAN-Phosphoserine658 def: "Protein FLNB_HUMAN with the residue 658 substituted with Phosphoserine" [UniProtKB:O75369] xref: UniProtKB:O75369 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:B0043276 name: FLNB_HUMAN-Phosphoserine983 def: "Protein FLNB_HUMAN with the residue 983 substituted with Phosphoserine" [UniProtKB:O75369] xref: UniProtKB:O75369 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:B0043277 name: FLNB_HUMAN-Phosphoserine2369 def: "Protein FLNB_HUMAN with the residue 2369 substituted with Phosphoserine" [UniProtKB:O75369] xref: UniProtKB:O75369 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:B0043278 name: FLNB_HUMAN-Phosphotyrosine2502 def: "Protein FLNB_HUMAN with the residue 2502 substituted with Phosphotyrosine" [UniProtKB:O75369] xref: UniProtKB:O75369 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:B0043279 name: FLNC_HUMAN-Phosphoserine1161 def: "Protein FLNC_HUMAN with the residue 1161 substituted with Phosphoserine" [UniProtKB:Q14315] xref: UniProtKB:Q14315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041399 ! FLNC_HUMAN [Term] id: CCO:B0043280 name: GABR2_HUMAN-Phosphoserine884 def: "Protein GABR2_HUMAN with the residue 884 substituted with Phosphoserine" [UniProtKB:O75899] xref: UniProtKB:O75899 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0041922 ! GABR2_HUMAN [Term] id: CCO:B0043281 name: GBRA4_HUMAN-Phosphoserine140 def: "Protein GBRA4_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P48169] xref: UniProtKB:P48169 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001242 ! GABA-A receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001957 ! benzodiazepine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0022898 ! GBRA4_HUMAN [Term] id: CCO:B0043282 name: GBRA4_HUMAN-Phosphoserine142 def: "Protein GBRA4_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:P48169] xref: UniProtKB:P48169 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022898 ! GBRA4_HUMAN [Term] id: CCO:B0043283 name: GLIS2_HUMAN-Phosphoserine245 def: "Protein GLIS2_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:Q9BZE0] xref: UniProtKB:Q9BZE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0020930 ! GLIS2_HUMAN [Term] id: CCO:B0043286 name: GRM1_HUMAN-Phosphotyrosine672 def: "Protein GRM1_HUMAN with the residue 672 substituted with Phosphotyrosine" [UniProtKB:Q13255] xref: UniProtKB:Q13255 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042245 ! GRM1_HUMAN [Term] id: CCO:B0043287 name: GRM7_HUMAN-Phosphoserine900 def: "Protein GRM7_HUMAN with the residue 900 substituted with Phosphoserine" [UniProtKB:Q14831] comment: By similarity xref: UniProtKB:Q14831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042227 ! GRM7_HUMAN [Term] id: CCO:B0043289 name: HIF3A_HUMAN-4-hydroxyproline492 def: "Protein HIF3A_HUMAN with the residue 492 substituted with 4-hydroxyproline" [UniProtKB:Q9Y2N7] xref: UniProtKB:Q9Y2N7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042408 ! HIF3A_HUMAN [Term] id: CCO:B0043290 name: IF2A_HUMAN-Phosphoserine49 def: "Protein IF2A_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:P05198] comment: by HRI; By similarity xref: UniProtKB:P05198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000410 ! polysome relationship: located_in CCO:C0000416 ! eukaryotic translation initiation factor 2 complex relationship: located_in CCO:C0000417 ! eukaryotic translation initiation factor 2B complex relationship: transformation_of CCO:B0041436 ! IF2A_HUMAN [Term] id: CCO:B0043291 name: IF2A_HUMAN-Phosphoserine52 def: "Protein IF2A_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:P05198] comment: by EIF2AK3, GCN2, HRI and PKR; By similarity xref: UniProtKB:P05198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041436 ! IF2A_HUMAN [Term] id: CCO:B0043316 name: LUC7L_HUMAN-Phosphoserine363 def: "Protein LUC7L_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q9NQ29] xref: UniProtKB:Q9NQ29 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025768 ! LUC7L_HUMAN [Term] id: CCO:B0043317 name: M4K4_HUMAN-Phosphothreonine181 def: "Protein M4K4_HUMAN with the residue 181 substituted with Phosphothreonine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043318 name: M4K4_HUMAN-Phosphoserine602 def: "Protein M4K4_HUMAN with the residue 602 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043319 name: M4K4_HUMAN-Phosphoserine629 def: "Protein M4K4_HUMAN with the residue 629 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043320 name: M4K4_HUMAN-Phosphoserine631 def: "Protein M4K4_HUMAN with the residue 631 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043321 name: M4K4_HUMAN-Phosphoserine639 def: "Protein M4K4_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043322 name: M4K4_HUMAN-Phosphoserine692 def: "Protein M4K4_HUMAN with the residue 692 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043323 name: M4K4_HUMAN-Phosphoserine696 def: "Protein M4K4_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043324 name: M4K4_HUMAN-Phosphoserine801 def: "Protein M4K4_HUMAN with the residue 801 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043325 name: M4K4_HUMAN-Phosphoserine805 def: "Protein M4K4_HUMAN with the residue 805 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043326 name: M4K4_HUMAN-Phosphoserine900 def: "Protein M4K4_HUMAN with the residue 900 substituted with Phosphoserine" [UniProtKB:O95819] xref: UniProtKB:O95819 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041953 ! M4K4_HUMAN [Term] id: CCO:B0043327 name: MAFA_HUMAN-Phosphoserine14 def: "Protein MAFA_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q8NHW3] xref: UniProtKB:Q8NHW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0042185 ! MAFA_HUMAN [Term] id: CCO:B0043328 name: MAFA_HUMAN-Phosphoserine65 def: "Protein MAFA_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q8NHW3] xref: UniProtKB:Q8NHW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042185 ! MAFA_HUMAN [Term] id: CCO:B0043329 name: MINK1_HUMAN-Phosphoserine763 def: "Protein MINK1_HUMAN with the residue 763 substituted with Phosphoserine" [UniProtKB:Q8N4C8] xref: UniProtKB:Q8N4C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041947 ! MINK1_HUMAN [Term] id: CCO:B0043330 name: MINK1_HUMAN-Phosphoserine778 def: "Protein MINK1_HUMAN with the residue 778 substituted with Phosphoserine" [UniProtKB:Q8N4C8] xref: UniProtKB:Q8N4C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041947 ! MINK1_HUMAN [Term] id: CCO:B0043331 name: MINK1_HUMAN-Phosphoserine782 def: "Protein MINK1_HUMAN with the residue 782 substituted with Phosphoserine" [UniProtKB:Q8N4C8] xref: UniProtKB:Q8N4C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041947 ! MINK1_HUMAN [Term] id: CCO:B0043332 name: MINK1_HUMAN-Phosphoserine916 def: "Protein MINK1_HUMAN with the residue 916 substituted with Phosphoserine" [UniProtKB:Q8N4C8] comment: By similarity xref: UniProtKB:Q8N4C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041947 ! MINK1_HUMAN [Term] id: CCO:B0043334 name: MYO9B_HUMAN-Phosphoserine1290 def: "Protein MYO9B_HUMAN with the residue 1290 substituted with Phosphoserine" [UniProtKB:Q13459] xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0043335 name: MYO9B_HUMAN-Phosphothreonine1346 def: "Protein MYO9B_HUMAN with the residue 1346 substituted with Phosphothreonine" [UniProtKB:Q13459] xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0043336 name: NCOA4_HUMAN-Phosphoserine456 def: "Protein NCOA4_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:Q13772] xref: UniProtKB:Q13772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0041593 ! NCOA4_HUMAN [Term] id: CCO:B0043337 name: PAK2_HUMAN-Phosphothreonine60 def: "Protein PAK2_HUMAN with the residue 60 substituted with Phosphothreonine" [UniProtKB:Q13177] xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0043340 name: PK3CD_HUMAN-Phosphoserine1039 def: "Protein PK3CD_HUMAN with the residue 1039 substituted with Phosphoserine" [UniProtKB:O00329] comment: by autocatalysis; xref: UniProtKB:O00329 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0006278 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: transformation_of CCO:B0018352 ! PK3CD_HUMAN [Term] id: CCO:B0043345 name: RAGP1_HUMAN-Phosphothreonine409 def: "Protein RAGP1_HUMAN with the residue 409 substituted with Phosphothreonine" [UniProtKB:P46060] comment: by CDK2; xref: UniProtKB:P46060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037521 ! RAGP1_HUMAN [Term] id: CCO:B0043349 name: RGPS2_HUMAN-Phosphoserine308 def: "Protein RGPS2_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:Q86X27] xref: UniProtKB:Q86X27 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037994 ! RGPS2_HUMAN [Term] id: CCO:B0043350 name: RHG12_HUMAN-Phosphoserine201 def: "Protein RHG12_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0043351 name: RHG12_HUMAN-Phosphoserine206 def: "Protein RHG12_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q8IWW6] comment: By similarity xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0043352 name: RHG12_HUMAN-Phosphothreonine231 def: "Protein RHG12_HUMAN with the residue 231 substituted with Phosphothreonine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0043353 name: RHG12_HUMAN-Phosphoserine240 def: "Protein RHG12_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0043354 name: RHG12_HUMAN-Phosphotyrosine243 def: "Protein RHG12_HUMAN with the residue 243 substituted with Phosphotyrosine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0043355 name: RHG12_HUMAN-Phosphothreonine521 def: "Protein RHG12_HUMAN with the residue 521 substituted with Phosphothreonine" [UniProtKB:Q8IWW6] comment: By similarity xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0043356 name: RHG12_HUMAN-Phosphoserine592 def: "Protein RHG12_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0043357 name: RHG27_HUMAN-Phosphoserine216 def: "Protein RHG27_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q6ZUM4] comment: By similarity xref: UniProtKB:Q6ZUM4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041368 ! RHG27_HUMAN [Term] id: CCO:B0043358 name: RHG27_HUMAN-Phosphotyrosine228 def: "Protein RHG27_HUMAN with the residue 228 substituted with Phosphotyrosine" [UniProtKB:Q6ZUM4] comment: By similarity xref: UniProtKB:Q6ZUM4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004517 ! Rac GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0041368 ! RHG27_HUMAN [Term] id: CCO:B0043359 name: RHG27_HUMAN-Phosphoserine638 def: "Protein RHG27_HUMAN with the residue 638 substituted with Phosphoserine" [UniProtKB:Q6ZUM4] comment: By similarity xref: UniProtKB:Q6ZUM4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041368 ! RHG27_HUMAN [Term] id: CCO:B0043360 name: RS14_HUMAN-Phosphothreonine105 def: "Protein RS14_HUMAN with the residue 105 substituted with Phosphothreonine" [UniProtKB:P62263] xref: UniProtKB:P62263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:B0043361 name: RS14_HUMAN-Phosphothreonine107 def: "Protein RS14_HUMAN with the residue 107 substituted with Phosphothreonine" [UniProtKB:P62263] xref: UniProtKB:P62263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:B0043362 name: RTN3_HUMAN-Phosphoserine30 def: "Protein RTN3_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:O95197] xref: UniProtKB:O95197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041728 ! RTN3_HUMAN [Term] id: CCO:B0043363 name: RTN3_HUMAN-Phosphoserine243 def: "Protein RTN3_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:O95197] comment: By similarity xref: UniProtKB:O95197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041728 ! RTN3_HUMAN [Term] id: CCO:B0043364 name: RTN3_HUMAN-Phosphoserine735 def: "Protein RTN3_HUMAN with the residue 735 substituted with Phosphoserine" [UniProtKB:O95197] comment: By similarity xref: UniProtKB:O95197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0041728 ! RTN3_HUMAN [Term] id: CCO:B0043365 name: RTN4_HUMAN-Phosphoserine7 def: "Protein RTN4_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q9NQC3] xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043366 name: RTN4_HUMAN-Phosphoserine15 def: "Protein RTN4_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q9NQC3] xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043367 name: RTN4_HUMAN-Phosphoserine107 def: "Protein RTN4_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:Q9NQC3] xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043368 name: RTN4_HUMAN-Phosphoserine152 def: "Protein RTN4_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q9NQC3] comment: By similarity xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043369 name: RTN4_HUMAN-Phosphoserine182 def: "Protein RTN4_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q9NQC3] xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043370 name: RTN4_HUMAN-Phosphoserine184 def: "Protein RTN4_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:Q9NQC3] xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043371 name: RTN4_HUMAN-Phosphothreonine188 def: "Protein RTN4_HUMAN with the residue 188 substituted with Phosphothreonine" [UniProtKB:Q9NQC3] xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043372 name: RTN4_HUMAN-Phosphoserine446 def: "Protein RTN4_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:Q9NQC3] comment: By similarity xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043373 name: RTN4_HUMAN-Phosphoserine860 def: "Protein RTN4_HUMAN with the residue 860 substituted with Phosphoserine" [UniProtKB:Q9NQC3] comment: By similarity xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043374 name: RTN4_HUMAN-Phosphoserine863 def: "Protein RTN4_HUMAN with the residue 863 substituted with Phosphoserine" [UniProtKB:Q9NQC3] comment: By similarity xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043375 name: RTN4_HUMAN-Phosphoserine881 def: "Protein RTN4_HUMAN with the residue 881 substituted with Phosphoserine" [UniProtKB:Q9NQC3] comment: By similarity xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043376 name: RTN4_HUMAN-Phosphotyrosine889 def: "Protein RTN4_HUMAN with the residue 889 substituted with Phosphotyrosine" [UniProtKB:Q9NQC3] comment: By similarity xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0043380 name: SP16H_HUMAN-N-acetylalanine2 def: "Protein SP16H_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y5B9] xref: UniProtKB:Q9Y5B9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032537 ! SP16H_HUMAN [Term] id: CCO:B0043381 name: ST38L_HUMAN-N-acetylalanine2 def: "Protein ST38L_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y2H1] xref: UniProtKB:Q9Y2H1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015573 ! ST38L_HUMAN [Term] id: CCO:B0043382 name: STAR8_HUMAN-Phosphoserine238 def: "Protein STAR8_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q92502] comment: By similarity xref: UniProtKB:Q92502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0041421 ! STAR8_HUMAN [Term] id: CCO:B0043383 name: STK38_HUMAN-N-acetylalanine2 def: "Protein STK38_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q15208] xref: UniProtKB:Q15208 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015584 ! STK38_HUMAN [Term] id: CCO:B0043416 name: CLUA1_HUMAN def: "Clusterin-associated protein 1" [UniProtKB:Q96AJ1] xref: EMBL:AAH17070.3 xref: EMBL:BAA31618.1 xref: EMBL:BAB14523.1 xref: EMBL:BAB14542.1 xref: EMBL:BAD44779.1 xref: UniProtKB:O75138 xref: UniProtKB:Q65ZA3 xref: UniProtKB:Q96AJ1 xref: UniProtKB:Q9H8R4 xref: UniProtKB:Q9H8T1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014153 ! CLUAP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008675 ! cinp-cluap1 physical interaction [Term] id: CCO:B0043417 name: TRI39_HUMAN def: "Tripartite motif-containing protein 39" [UniProtKB:Q9HCM9] synonym: "RING finger protein 23" EXACT [UniProtKB:Q9HCM9] synonym: "Testis-abundant finger protein" EXACT [UniProtKB:Q9HCM9] xref: EMBL:AAH07661.1 xref: EMBL:AAH34985.1 xref: EMBL:AAP36034.1 xref: EMBL:BAB16374.1 xref: EMBL:BAD13703.1 xref: UniProtKB:Q76BL3 xref: UniProtKB:Q8IYT9 xref: UniProtKB:Q96IB6 xref: UniProtKB:Q9HCM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014179 ! TRIM39_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008676 ! trim39-ube2d1 physical interaction relationship: participates_in CCO:I0015445 ! plcd4-trim39 physical interaction relationship: participates_in CCO:I0015648 ! trim39-ube2d3 physical interaction relationship: transforms_into CCO:B0043495 ! TRI39_HUMAN-Phosphotyrosine439 [Term] id: CCO:B0043418 name: RN126_HUMAN def: "RING finger protein 126" [UniProtKB:Q9BV68] xref: EMBL:AAH01442.1 xref: EMBL:AAH25374.1 xref: EMBL:BAA91254.1 xref: UniProtKB:Q9BV68 xref: UniProtKB:Q9NWX1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014172 ! RNF126_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008682 ! rnf126-ube2d1 physical interaction relationship: participates_in CCO:I0015738 ! rnf126-ube2d3 physical interaction relationship: participates_in CCO:I0016729 ! map3k3-q9bv68 physical interaction relationship: participates_in CCO:I0017149 ! traf6-q9bv68 physical interaction [Term] id: CCO:B0043419 name: BBS2_HUMAN def: "Bardet-Biedl syndrome 2 protein" [UniProtKB:Q9BXC9] xref: EMBL:AAH14140.1 xref: EMBL:AAK28552.1 xref: EMBL:BAB55252.1 xref: UniProtKB:Q96CM0 xref: UniProtKB:Q96SN9 xref: UniProtKB:Q9BXC9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014149 ! BBS2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000484 ! basal body relationship: located_in CCO:C0001282 ! motile secondary cilium relationship: located_in CCO:C0002182 ! BBSome relationship: participates_in CCO:I0008683 ! bbs2-psme3 physical interaction [Term] id: CCO:B0043420 name: SERF2_HUMAN def: "Small EDRK-rich factor 2" [UniProtKB:P84101] synonym: "4F5rel" EXACT [UniProtKB:P84101] synonym: "Gastric cancer-related protein VRG107" EXACT [UniProtKB:P84101] synonym: "h4F5rel" EXACT [UniProtKB:P84101] xref: EMBL:AAC63516.1 xref: EMBL:AAH15491.2 xref: EMBL:AAK07636.1 xref: UniProtKB:O75918 xref: UniProtKB:O88891 xref: UniProtKB:P84101 xref: UniProtKB:Q9BZH7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014177 ! SERF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008684 ! psme3-serf2 physical interaction relationship: participates_in CCO:I0015216 ! pepp2-serf2 physical interaction relationship: participates_in CCO:I0015249 ! mdfi-serf2 physical interaction relationship: participates_in CCO:I0020451 ! serf2-chd3 physical interaction relationship: participates_in CCO:I0020479 ! th1l-serf2 physical interaction [Term] id: CCO:B0043421 name: TNNT1_HUMAN def: "Troponin T, slow skeletal muscle" [UniProtKB:P13805] synonym: "Slow skeletal muscle troponin T" EXACT [UniProtKB:P13805] synonym: "sTnT" EXACT [UniProtKB:P13805] synonym: "TnTs" EXACT [UniProtKB:P13805] xref: EMBL:AAA61204.1 xref: EMBL:AAA61205.1 xref: EMBL:AAB30272.1 xref: EMBL:AAB30273.1 xref: EMBL:AAD13978.1 xref: EMBL:AAH10963.1 xref: EMBL:AAH22086.2 xref: EMBL:AAH34143.1 xref: EMBL:CAA09750.1 xref: EMBL:CAA09751.1 xref: EMBL:CAA09752.1 xref: UniProtKB:O95472 xref: UniProtKB:P13805 xref: UniProtKB:Q16061 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014178 ! TNNT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008687 ! psmc5-tnnt1 physical interaction relationship: participates_in CCO:I0015424 ! ppfia1-tnnt1 physical interaction relationship: transforms_into CCO:B0043493 ! TNNT1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0043494 ! TNNT1_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0048414 ! TNNT1_HUMAN-Phosphotyrosine164 [Term] id: CCO:B0043422 name: CA216_HUMAN def: "UPF0500 protein C1orf216" [UniProtKB:Q8TAB5] xref: EMBL:AAH26909.1 xref: EMBL:BAC04755.1 xref: EMBL:BAC04799.1 xref: EMBL:EAX07403.1 xref: UniProtKB:Q8N8N6 xref: UniProtKB:Q8TAB5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014150 ! C1orf216_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008689 ! flj38984-psmc6 physical interaction [Term] id: CCO:B0043423 name: RASF8_HUMAN def: "Ras association domain-containing protein 8" [UniProtKB:Q8NHQ8] synonym: "Carcinoma-associated protein HOJ-1" EXACT [UniProtKB:Q8NHQ8] xref: EMBL:AAC95425.1 xref: EMBL:AAH30021.1 xref: EMBL:AAV54603.1 xref: EMBL:BAC98838.1 xref: UniProtKB:O95647 xref: UniProtKB:Q5SCI2 xref: UniProtKB:Q76KB6 xref: UniProtKB:Q8NHQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014168 ! RASSF8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008690 ! c12orf2-psmd4 physical interaction relationship: participates_in CCO:I0015012 ! c12orf2-frmd6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0048368 ! RASF8_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0048369 ! RASF8_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0069754 ! RASF8_HUMAN-Phosphoserine105 [Term] id: CCO:B0043424 name: KCD17_HUMAN def: "BTB/POZ domain-containing protein KCTD17" [UniProtKB:Q8N5Z5] xref: EMBL:AAH25403.1 xref: EMBL:AAH31038.1 xref: EMBL:BAB14007.1 xref: EMBL:CAQ07355.1 xref: EMBL:CAQ07356.1 xref: EMBL:EAW60139.1 xref: UniProtKB:B0QYA9 xref: UniProtKB:B0QYB0 xref: UniProtKB:O95517 xref: UniProtKB:Q8N5Z5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014164 ! KCTD17_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008692 ! kctd17-psma1 physical interaction relationship: participates_in CCO:I0015320 ! kctd17-nif3l1 physical interaction [Term] id: CCO:B0043425 name: IP3KB_HUMAN def: "Inositol-trisphosphate 3-kinase B" [UniProtKB:P27987] synonym: "EC 2.7.1.127" EXACT [UniProtKB:P27987] synonym: "Inositol 1,4,5-trisphosphate 3-kinase B" EXACT [UniProtKB:P27987] synonym: "IP3 3-kinase B" EXACT [UniProtKB:P27987] synonym: "IP3K B" EXACT [UniProtKB:P27987] synonym: "IP3K-B" EXACT [UniProtKB:P27987] xref: EMBL:AAH15009.1 xref: EMBL:CAA40491.1 xref: EMBL:CAB65055.3 xref: EMBL:CAC40650.1 xref: EMBL:CAH70187.1 xref: EMBL:CAH70188.1 xref: UniProtKB:P27987 xref: UniProtKB:Q5VWL9 xref: UniProtKB:Q5VWM0 xref: UniProtKB:Q96BZ2 xref: UniProtKB:Q96JS1 xref: UniProtKB:Q9UH47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014163 ! ITPKB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001903 ! inositol trisphosphate 3-kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008693 ! itpkb-psme3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0043470 ! IP3KB_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0043471 ! IP3KB_HUMAN-Phosphoserine49 [Term] id: CCO:B0043426 name: TRIM9_HUMAN def: "Tripartite motif-containing protein 9" [UniProtKB:Q9C026] synonym: "RING finger protein 91" EXACT [UniProtKB:Q9C026] xref: EMBL:AAG53490.1 xref: EMBL:AAG53491.1 xref: EMBL:AAG53492.1 xref: EMBL:AAH13414.1 xref: EMBL:AAH63872.1 xref: EMBL:BAA13398.2 xref: EMBL:BAB70913.1 xref: UniProtKB:Q92557 xref: UniProtKB:Q96D24 xref: UniProtKB:Q96NI4 xref: UniProtKB:Q9C025 xref: UniProtKB:Q9C026 xref: UniProtKB:Q9C027 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014180 ! TRIM9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0008695 ! btrc-trim9 physical interaction relationship: transforms_into CCO:B0048416 ! TRIM9_HUMAN-Phosphoserine46 [Term] id: CCO:B0043427 name: PSME2_HUMAN def: "Proteasome activator complex subunit 2" [UniProtKB:Q9UL46] synonym: "11S regulator complex subunit beta" EXACT [UniProtKB:Q9UL46] synonym: "Activator of multicatalytic protease subunit 2" EXACT [UniProtKB:Q9UL46] synonym: "PA28b" EXACT [UniProtKB:Q9UL46] synonym: "PA28beta" EXACT [UniProtKB:Q9UL46] synonym: "Proteasome activator 28 subunit beta" EXACT [UniProtKB:Q9UL46] synonym: "REG-beta" EXACT [UniProtKB:Q9UL46] xref: EMBL:AAF02218.1 xref: EMBL:AAH04368.1 xref: EMBL:AAH19885.1 xref: EMBL:AAH72025.1 xref: EMBL:BAA08205.1 xref: UniProtKB:Q15129 xref: UniProtKB:Q9UL46 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014167 ! PSME2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0008698 ! psme1-psme2 physical interaction relationship: transforms_into CCO:B0043477 ! PSME2_HUMAN-N-acetylalanine2 [Term] id: CCO:B0043428 name: NCOA3_HUMAN def: "Nuclear receptor coactivator 3" [UniProtKB:Q9Y6Q9] synonym: "ACTR" EXACT [UniProtKB:Q9Y6Q9] synonym: "AIB-1" EXACT [UniProtKB:Q9Y6Q9] synonym: "Amplified in breast cancer-1 protein" EXACT [UniProtKB:Q9Y6Q9] synonym: "CBP-interacting protein" EXACT [UniProtKB:Q9Y6Q9] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q9Y6Q9] synonym: "NCoA-3" EXACT [UniProtKB:Q9Y6Q9] synonym: "pCIP" EXACT [UniProtKB:Q9Y6Q9] synonym: "RAC-3" EXACT [UniProtKB:Q9Y6Q9] synonym: "Receptor-associated coactivator 3" EXACT [UniProtKB:Q9Y6Q9] synonym: "SRC-3" EXACT [UniProtKB:Q9Y6Q9] synonym: "Steroid receptor coactivator protein 3" EXACT [UniProtKB:Q9Y6Q9] synonym: "Thyroid hormone receptor activator molecule 1" EXACT [UniProtKB:Q9Y6Q9] synonym: "TRAM-1" EXACT [UniProtKB:Q9Y6Q9] xref: EMBL:AAB92368.1 xref: EMBL:AAC51663.1 xref: EMBL:AAC51677.1 xref: EMBL:AAC51849.1 xref: EMBL:CAB40662.1 xref: EMBL:CAC17693.1 xref: EMBL:CAI42141.1 xref: UniProtKB:Q5JYD9 xref: UniProtKB:Q5JYE0 xref: UniProtKB:Q9BR49 xref: UniProtKB:Q9UPC9 xref: UniProtKB:Q9UPG4 xref: UniProtKB:Q9UPG7 xref: UniProtKB:Q9Y6Q9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014165 ! NCOA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008700 ! ncoa3-psme3-2 physical interaction relationship: participates_in CCO:I0008702 ! ncoa3-psme3 physical interaction relationship: participates_in CCO:I0008769 ! ncoa3-psme3-1 physical interaction relationship: participates_in CCO:I0008790 ! ncoa3-psme3-3 direct interaction relationship: participates_in CCO:I0008791 ! ncoa3-psme3-4 direct interaction relationship: participates_in CCO:I0017310 ! ikbkb-ncoa3-2 physical interaction relationship: participates_in CCO:I0018211 ! ncoa3-crebbp-ncoa2-1 physical interaction relationship: participates_in CCO:I0018212 ! ncoa3-ikbkb physical interaction relationship: participates_in CCO:I0018294 ! ncoa3-ikbkb-1 physical interaction relationship: participates_in CCO:I0018356 ! ncoa3-ikbkg-1 physical interaction relationship: participates_in CCO:I0018527 ! ncoa3-chuk physical interaction relationship: participates_in CCO:I0018719 ! esr1-foxo1a-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0043472 ! NCOA3_HUMAN-N6-acetyllysine616 relationship: transforms_into CCO:B0043473 ! NCOA3_HUMAN-N6-acetyllysine619 relationship: transforms_into CCO:B0043474 ! NCOA3_HUMAN-N6-acetyllysine620 relationship: transforms_into CCO:B0043475 ! NCOA3_HUMAN-Phosphoserine857 relationship: transforms_into CCO:B0043476 ! NCOA3_HUMAN-Phosphoserine867 relationship: transforms_into CCO:B0068478 ! NCOA3_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0068479 ! NCOA3_HUMAN-Phosphoserine551 relationship: transforms_into CCO:B0068480 ! NCOA3_HUMAN-Phosphoserine728 [Term] id: CCO:B0043429 name: XRN2_HUMAN def: "5'-3' exoribonuclease 2" [UniProtKB:Q9H0D6] synonym: "DHM1-like protein" EXACT [UniProtKB:Q9H0D6] synonym: "DHP protein" EXACT [UniProtKB:Q9H0D6] synonym: "EC 3.1.13.-" EXACT [UniProtKB:Q9H0D6] xref: EMBL:AAD55138.1 xref: EMBL:AAH06417.2 xref: EMBL:AAQ13577.1 xref: EMBL:AAR24369.1 xref: EMBL:BAA90934.1 xref: EMBL:CAB66775.1 xref: EMBL:CAH71495.1 xref: EMBL:CAI19756.1 xref: UniProtKB:Q3L8N4 xref: UniProtKB:Q6KGZ9 xref: UniProtKB:Q9BQL1 xref: UniProtKB:Q9H0D6 xref: UniProtKB:Q9NTW0 xref: UniProtKB:Q9NXS6 xref: UniProtKB:Q9UL53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014182 ! XRN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008723 ! xrn2-psma3 physical interaction relationship: participates_in CCO:I0015891 ! lsm3-xrn2 physical interaction relationship: participates_in CCO:I0015892 ! xrn2-pmscl2 physical interaction relationship: participates_in CCO:I0015893 ! xrn2-exosc8 physical interaction relationship: participates_in CCO:I0017330 ! xrn2-itgb4bp physical interaction relationship: participates_in CCO:I0017331 ! xrn2-eif3s6ip physical interaction relationship: participates_in CCO:I0017332 ! xrn2-dkfzp686n0351 physical interaction relationship: participates_in CCO:I0017333 ! xrn2-comt physical interaction relationship: participates_in CCO:I0017334 ! xrn2-mocs3 physical interaction relationship: participates_in CCO:I0017335 ! xrn2-tollip physical interaction relationship: participates_in CCO:I0017336 ! xrn2-tardbp physical interaction relationship: participates_in CCO:I0017474 ! disc1-xrn2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0043504 ! XRN2_HUMAN-Phosphoserine448 relationship: transforms_into CCO:B0043505 ! XRN2_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0043506 ! XRN2_HUMAN-Phosphoserine499 relationship: transforms_into CCO:B0043507 ! XRN2_HUMAN-Phosphoserine501 relationship: transforms_into CCO:B0071897 ! XRN2_HUMAN-Phosphothreonine439 [Term] id: CCO:B0043430 name: RNF5_HUMAN def: "E3 ubiquitin-protein ligase RNF5" [UniProtKB:Q99942] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q99942] synonym: "HsRma1" EXACT [UniProtKB:Q99942] synonym: "Protein G16" EXACT [UniProtKB:Q99942] synonym: "RING finger protein 5" EXACT [UniProtKB:Q99942] xref: EMBL:AAB47492.1 xref: EMBL:AAH04155.1 xref: EMBL:AAI11393.1 xref: EMBL:AAI19742.1 xref: EMBL:AAI19743.1 xref: EMBL:AAI27652.1 xref: EMBL:AAI27653.1 xref: EMBL:AAI48256.1 xref: EMBL:AAP35769.1 xref: EMBL:BAB39359.1 xref: EMBL:CAB51286.1 xref: EMBL:CAI17532.1 xref: EMBL:CAI18351.1 xref: EMBL:CAI41808.1 xref: EMBL:CAM26222.1 xref: EMBL:CAQ06594.1 xref: EMBL:CAQ09623.1 xref: EMBL:CAQ10698.1 xref: UniProtKB:A2BFI6 xref: UniProtKB:Q0VDB7 xref: UniProtKB:Q99942 xref: UniProtKB:Q9UMQ2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014173 ! RNF5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008771 ! hsrma1-ube2e1 physical interaction relationship: participates_in CCO:I0017927 ! pxn-rnf5-2 physical interaction relationship: participates_in CCO:I0017928 ! pxn-rnf5-3 physical interaction relationship: participates_in CCO:I0017929 ! rnf5-pxn-1 physical interaction relationship: participates_in CCO:I0017934 ! rma1-cftr colocalization relationship: participates_in CCO:I0018374 ! rnf5-pxn-2 physical interaction relationship: participates_in CCO:I0018375 ! rnf5-pxn-4 physical interaction relationship: participates_in CCO:I0018445 ! hsrma1-ubch9 physical interaction relationship: participates_in CCO:I0018446 ! hsrma1-ube2d3 physical interaction relationship: participates_in CCO:I0018562 ! rma1-cftr-4 physical interaction relationship: participates_in CCO:I0019460 ! rma1-cftr-1 physical interaction relationship: participates_in CCO:I0019516 ! pxn-rnf5-4 physical interaction [Term] id: CCO:B0043431 name: FBXL7_HUMAN def: "F-box/LRR-repeat protein 7" [UniProtKB:Q9UJT9] synonym: "F-box and leucine-rich repeat protein 7" EXACT [UniProtKB:Q9UJT9] synonym: "F-box protein FBL6/FBL7" EXACT [UniProtKB:Q9UJT9] xref: EMBL:AAF04514.1 xref: EMBL:AAF09248.1 xref: EMBL:AAH75061.1 xref: EMBL:BAA74863.2 xref: UniProtKB:O94926 xref: UniProtKB:Q9UJT9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014158 ! FBXL7_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: participates_in CCO:I0008774 ! fbxl7-skp1 physical interaction [Term] id: CCO:B0043432 name: FBXW2_HUMAN def: "F-box/WD repeat-containing protein 2" [UniProtKB:Q9UKT8] synonym: "F-box and WD-40 domain-containing protein 2" EXACT [UniProtKB:Q9UKT8] synonym: "Protein MD6" EXACT [UniProtKB:Q9UKT8] xref: EMBL:AAF04465.1 xref: EMBL:AAF13226.1 xref: EMBL:AAH18738.1 xref: EMBL:AAI10335.1 xref: EMBL:AAP97276.1 xref: EMBL:AAP97280.1 xref: EMBL:BAB14051.1 xref: EMBL:CAI95113.1 xref: UniProtKB:Q4VXH2 xref: UniProtKB:Q7Z4V6 xref: UniProtKB:Q8WV51 xref: UniProtKB:Q9HA09 xref: UniProtKB:Q9UKA3 xref: UniProtKB:Q9UKT8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014159 ! FBXW2_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008775 ! fbxl2-skp1 physical interaction [Term] id: CCO:B0043433 name: FBXW5_HUMAN def: "F-box/WD repeat-containing protein 5" [UniProtKB:Q969U6] synonym: "F-box and WD-40 domain-containing protein 5" EXACT [UniProtKB:Q969U6] xref: EMBL:AAG17240.1 xref: EMBL:AAG23772.1 xref: EMBL:AAH00850.1 xref: EMBL:AAH04541.2 xref: EMBL:AAH09429.1 xref: EMBL:AAH14130.1 xref: EMBL:AAH14297.1 xref: EMBL:BAB15354.1 xref: EMBL:CAB70851.1 xref: EMBL:CAI12741.1 xref: EMBL:CAI12743.1 xref: EMBL:CAI12746.1 xref: UniProtKB:Q5SPZ8 xref: UniProtKB:Q5SPZ9 xref: UniProtKB:Q5SQ02 xref: UniProtKB:Q5SQ03 xref: UniProtKB:Q5SQ04 xref: UniProtKB:Q8WY79 xref: UniProtKB:Q969U6 xref: UniProtKB:Q96GJ6 xref: UniProtKB:Q9BSU8 xref: UniProtKB:Q9H6A8 xref: UniProtKB:Q9HBQ6 xref: UniProtKB:Q9NSZ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014160 ! FBXW5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008776 ! fbw5-skp1 physical interaction relationship: participates_in CCO:I0015415 ! fbxw5-mdfi physical interaction [Term] id: CCO:B0043434 name: FBXW8_HUMAN def: "F-box/WD repeat-containing protein 8" [UniProtKB:Q8N3Y1] synonym: "F-box and WD-40 domain-containing protein 8" EXACT [UniProtKB:Q8N3Y1] synonym: "F-box only protein 29" EXACT [UniProtKB:Q8N3Y1] xref: EMBL:AAF03129.1 xref: EMBL:AAH37296.1 xref: UniProtKB:Q8N3Y1 xref: UniProtKB:Q9UK95 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014161 ! FBXW8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008777 ! fbw6-skp1 physical interaction relationship: transforms_into CCO:B0043469 ! FBXW8_HUMAN-Phosphoserine85 [Term] id: CCO:B0043435 name: FBX41_HUMAN def: "F-box only protein 41" [UniProtKB:Q8TF61] xref: EMBL:BAB85526.1 xref: UniProtKB:Q8TF61 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014157 ! FBXO41_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0008779 ! fbxo41-skp1 physical interaction relationship: transforms_into CCO:B0043463 ! FBX41_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0043464 ! FBX41_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0043465 ! FBX41_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0043466 ! FBX41_HUMAN-Phosphoserine478 relationship: transforms_into CCO:B0043467 ! FBX41_HUMAN-Phosphothreonine479 relationship: transforms_into CCO:B0043468 ! FBX41_HUMAN-Phosphoserine547 [Term] id: CCO:B0043436 name: PRIO_HUMAN def: "Major prion protein precursor" [UniProtKB:P04156] synonym: "ASCR" EXACT [UniProtKB:P04156] synonym: "CD230 antigen" EXACT [UniProtKB:P04156] synonym: "PrP" EXACT [UniProtKB:P04156] synonym: "PrP27-30" EXACT [UniProtKB:P04156] synonym: "PrP33-35C" EXACT [UniProtKB:P04156] xref: EMBL:AAA19664.1 xref: EMBL:AAA60182.1 xref: EMBL:AAB20521.1 xref: EMBL:AAB20522.1 xref: EMBL:AAB20523.1 xref: EMBL:AAB50648.2 xref: EMBL:AAB50649.2 xref: EMBL:AAB59442.1 xref: EMBL:AAB59443.1 xref: EMBL:AAC05365.1 xref: EMBL:AAC78725.1 xref: EMBL:AAD46098.1 xref: EMBL:AAG21693.1 xref: EMBL:AAH12844.1 xref: EMBL:AAH22532.1 xref: EMBL:ABD63004.1 xref: EMBL:BAA00011.1 xref: EMBL:CAA58442.1 xref: EMBL:CAB75503.1 xref: UniProtKB:O60489 xref: UniProtKB:P04156 xref: UniProtKB:P78446 xref: UniProtKB:Q15216 xref: UniProtKB:Q15221 xref: UniProtKB:Q27H91 xref: UniProtKB:Q8TBG0 xref: UniProtKB:Q96E70 xref: UniProtKB:Q9UP19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014166 ! PRNP_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:I0008787 ! prnp-psma3 physical interaction relationship: participates_in CCO:I0017581 ! tsc22d4-prnp physical interaction relationship: participates_in CCO:I0020413 ! prnp-bat3 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0043437 name: RERE_HUMAN def: "Arginine-glutamic acid dipeptide repeats protein" [UniProtKB:Q9P2R6] synonym: "Atrophin-1-like protein" EXACT [UniProtKB:Q9P2R6] synonym: "Atrophin-1-related protein" EXACT [UniProtKB:Q9P2R6] xref: EMBL:AAC28264.1 xref: EMBL:AAC31120.1 xref: EMBL:AAD27584.1 xref: EMBL:BAA32303.3 xref: EMBL:BAA95898.1 xref: EMBL:CAH70516.1 xref: EMBL:CAH73433.1 xref: EMBL:CAI19208.1 xref: UniProtKB:O43393 xref: UniProtKB:O75046 xref: UniProtKB:O75359 xref: UniProtKB:Q5VXL9 xref: UniProtKB:Q6P6B9 xref: UniProtKB:Q9P2R6 xref: UniProtKB:Q9Y2W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014170 ! RERE_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008788 ! rere-psma3 physical interaction relationship: participates_in CCO:I0008789 ! rere-psma3-1 physical interaction relationship: participates_in CCO:I0017582 ! trim22-rere physical interaction relationship: participates_in CCO:I0017621 ! rere-krtap4_12 physical interaction relationship: participates_in CCO:I0017622 ! rere-plscr1 physical interaction relationship: participates_in CCO:I0018940 ! atn1-rere physical interaction relationship: participates_in CCO:I0019157 ! rere-atn1 physical interaction relationship: participates_in CCO:I0019158 ! rere-cbfa2t2 physical interaction relationship: participates_in CCO:I0019159 ! rere-efemp2 physical interaction relationship: participates_in CCO:I0019160 ! rere-prkcbp1 physical interaction relationship: participates_in CCO:I0019161 ! rere-atn1-1 physical interaction relationship: participates_in CCO:I0019162 ! rere-bat2 physical interaction relationship: participates_in CCO:I0019163 ! rere-cxorf45 physical interaction relationship: participates_in CCO:I0019164 ! rere-ecm1 physical interaction relationship: participates_in CCO:I0019165 ! rere-efemp1 physical interaction relationship: participates_in CCO:I0019166 ! rere-efemp2-1 physical interaction relationship: participates_in CCO:I0019167 ! rere-myst3 physical interaction relationship: participates_in CCO:I0019168 ! rere-rbm9 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0043484 ! RERE_HUMAN-Phosphoserine594 relationship: transforms_into CCO:B0043485 ! RERE_HUMAN-Phosphothreonine599 relationship: transforms_into CCO:B0043486 ! RERE_HUMAN-Phosphoserine600 relationship: transforms_into CCO:B0043487 ! RERE_HUMAN-Phosphoserine613 relationship: transforms_into CCO:B0043488 ! RERE_HUMAN-Phosphoserine656 relationship: transforms_into CCO:B0043489 ! RERE_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0043490 ! RERE_HUMAN-Phosphoserine679 relationship: transforms_into CCO:B0048374 ! RERE_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0048375 ! RERE_HUMAN-Phosphoserine1106 relationship: transforms_into CCO:B0048376 ! RERE_HUMAN-Phosphoserine1113 relationship: transforms_into CCO:B0048377 ! RERE_HUMAN-Phosphoserine1115 relationship: transforms_into CCO:B0069880 ! RERE_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0069881 ! RERE_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0069882 ! RERE_HUMAN-Phosphoserine642 [Term] id: CCO:B0043438 name: RUXF_HUMAN def: "Small nuclear ribonucleoprotein F" [UniProtKB:P62306] synonym: "Sm protein F" EXACT [UniProtKB:P62306] synonym: "Sm-F" EXACT [UniProtKB:P62306] synonym: "SmF" EXACT [UniProtKB:P62306] synonym: "snRNP-F" EXACT [UniProtKB:P62306] xref: EMBL:AAH02505.3 xref: EMBL:AAH63397.2 xref: EMBL:AAI28453.1 xref: EMBL:AAI28454.1 xref: EMBL:CAA59688.1 xref: EMBL:CAG33032.1 xref: UniProtKB:A2VCR2 xref: UniProtKB:P62306 xref: UniProtKB:Q15356 xref: UniProtKB:Q6IBQ1 xref: UniProtKB:Q6P4I0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014176 ! SNRPF_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: participates_in CCO:I0008797 ! snrpf-psma3 physical interaction relationship: participates_in CCO:I0016652 ! map3k1-snrpf physical interaction [Term] id: CCO:B0043439 name: VINC_HUMAN def: "Vinculin" [UniProtKB:P18206] synonym: "Metavinculin" EXACT [UniProtKB:P18206] xref: EMBL:AAA61271.1 xref: EMBL:AAA61283.1 xref: EMBL:AAB21656.1 xref: EMBL:AAB21657.1 xref: EMBL:AAH39174.1 xref: EMBL:CAD97952.1 xref: EMBL:CAI13972.1 xref: EMBL:CAI39673.1 xref: UniProtKB:P18206 xref: UniProtKB:Q16450 xref: UniProtKB:Q5SWX2 xref: UniProtKB:Q7Z3B8 xref: UniProtKB:Q8IXU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014181 ! VCL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008799 ! psme1-vcl physical interaction relationship: participates_in CCO:I0015068 ! abi2-vcl physical interaction relationship: participates_in CCO:I0015795 ! trip6-vcl physical interaction relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: transforms_into CCO:B0043496 ! VINC_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: transforms_into CCO:B0043498 ! VINC_HUMAN-Phosphothreonine508 relationship: transforms_into CCO:B0043499 ! VINC_HUMAN-Phosphotyrosine537 relationship: transforms_into CCO:B0043500 ! VINC_HUMAN-Phosphothreonine604 relationship: transforms_into CCO:B0043501 ! VINC_HUMAN-Phosphoserine721 relationship: transforms_into CCO:B0043502 ! VINC_HUMAN-Phosphoserine774 relationship: transforms_into CCO:B0043503 ! VINC_HUMAN-Phosphotyrosine822 relationship: transforms_into CCO:B0048422 ! VINC_HUMAN-Phosphotyrosine100 relationship: transforms_into CCO:B0048423 ! VINC_HUMAN-Phosphotyrosine1133 relationship: transforms_into CCO:B0071801 ! VINC_HUMAN-Phosphotyrosine692 [Term] id: CCO:B0043440 name: RSMB_HUMAN def: "Small nuclear ribonucleoprotein-associated proteins B and B'" [UniProtKB:P14678] synonym: "Sm protein B/B'" EXACT [UniProtKB:P14678] synonym: "Sm-B/Sm-B'" EXACT [UniProtKB:P14678] synonym: "SmB/SmB'" EXACT [UniProtKB:P14678] synonym: "snRNP-B" EXACT [UniProtKB:P14678] xref: EMBL:AAA36578.1 xref: EMBL:AAA36579.1 xref: EMBL:AAD54488.1 xref: EMBL:CAA33902.1 xref: EMBL:CAA37170.1 xref: EMBL:CAA37171.1 xref: EMBL:CAB46714.1 xref: EMBL:CAB46715.1 xref: EMBL:CAB57867.1 xref: EMBL:CAB57868.1 xref: UniProtKB:P14678 xref: UniProtKB:Q15490 xref: UniProtKB:Q9UIS5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014174 ! SNRPB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008802 ! snrpb-psma3 physical interaction relationship: participates_in CCO:I0019911 ! ascc2-snrpb physical interaction relationship: transforms_into CCO:B0043491 ! RSMB_HUMAN-Omega-N-methylated arginine108 relationship: transforms_into CCO:B0043492 ! RSMB_HUMAN-Omega-N-methylated arginine112 [Term] id: CCO:B0043441 name: EZH2_HUMAN def: "Polycomb protein EZH2" [UniProtKB:Q15910] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q15910] synonym: "Enhancer of zeste homolog 2" EXACT [UniProtKB:Q15910] synonym: "ENX-1" EXACT [UniProtKB:Q15910] synonym: "Lysine N-methyltransferase 6" EXACT [UniProtKB:Q15910] xref: EMBL:AAC50591.1 xref: EMBL:AAC51520.1 xref: EMBL:CAA64955.1 xref: UniProtKB:Q15755 xref: UniProtKB:Q15910 xref: UniProtKB:Q92857 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014155 ! EZH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008804 ! ezh2-psmb6 physical interaction relationship: participates_in CCO:I0017520 ! ezh2-dnmt1 physical interaction relationship: participates_in CCO:I0017521 ! ezh2-dnmt3a physical interaction relationship: participates_in CCO:I0017522 ! ezh2-dnmt3b physical interaction relationship: participates_in CCO:I0017732 ! dnmt1-ezh2-2 physical interaction relationship: participates_in CCO:I0017733 ! dnm3a-ezh2 physical interaction relationship: participates_in CCO:I0017734 ! dnm3b-ezh2 physical interaction relationship: participates_in CCO:I0019291 ! dnmt1-ezh2 physical interaction relationship: participates_in CCO:I0019292 ! dnmt3a-ezh2 physical interaction relationship: participates_in CCO:I0019293 ! dnmt3b-ezh2 physical interaction relationship: participates_in CCO:I0019294 ! dnmt1-ezh2-1 physical interaction relationship: participates_in CCO:I0019714 ! ezh2-pola2 physical interaction relationship: participates_in CCO:I0020306 ! ezh2-wsb2 physical interaction relationship: transforms_into CCO:B0043461 ! EZH2_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0043462 ! EZH2_HUMAN-Phosphothreonine487 relationship: transforms_into CCO:B0048257 ! EZH2_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0065187 ! EZH2_HUMAN-Phosphothreonine339 relationship: transforms_into CCO:B0065188 ! EZH2_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0065189 ! EZH2_HUMAN-Phosphothreonine367 [Term] id: CCO:B0043442 name: FBX34_HUMAN def: "F-box only protein 34" [UniProtKB:Q9NWN3] xref: EMBL:AAI09121.1 xref: EMBL:AAI09122.1 xref: EMBL:BAA91346.1 xref: EMBL:CAD62596.1 xref: EMBL:CAG33530.1 xref: UniProtKB:Q2VPB5 xref: UniProtKB:Q86TY4 xref: UniProtKB:Q9NWN3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014156 ! FBXO34_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008805 ! fbxo34-skp1a physical interaction relationship: participates_in CCO:I0008806 ! skp1a-fbxo34 physical interaction [Term] id: CCO:B0043443 name: CENA1_HUMAN def: "Centaurin-alpha-1" [UniProtKB:O75689] synonym: "Putative MAPK-activating protein PM25" EXACT [UniProtKB:O75689] xref: EMBL:AAD11414.1 xref: EMBL:AAH33747.1 xref: EMBL:BAC77402.1 xref: EMBL:CAA07024.1 xref: EMBL:EAL23709.1 xref: EMBL:EAW87183.1 xref: UniProtKB:A4D2Q2 xref: UniProtKB:O75689 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014152 ! CENTA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008809 ! psme3-centa1 physical interaction relationship: participates_in CCO:I0019922 ! q6zuh1-centa1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0043459 ! CENA1_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0043460 ! CENA1_HUMAN-Phosphothreonine276 [Term] id: CCO:B0043444 name: CBWD3_HUMAN def: "COBW domain-containing protein 3" [UniProtKB:Q5JTY5] synonym: "Cobalamin synthetase W domain-containing protein 3" EXACT [UniProtKB:Q5JTY5] xref: EMBL:CAI41162.1 xref: UniProtKB:Q5JTY5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014151 ! CBWD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008812 ! ube2e1-cbwd3 physical interaction [Term] id: CCO:B0043445 name: HEXA_HUMAN def: "Beta-hexosaminidase subunit alpha precursor" [UniProtKB:P06865] synonym: "Beta-N-acetylhexosaminidase subunit alpha" EXACT [UniProtKB:P06865] synonym: "EC 3.2.1.52" EXACT [UniProtKB:P06865] synonym: "Hexosaminidase subunit A" EXACT [UniProtKB:P06865] synonym: "N-acetyl-beta-glucosaminidase subunit alpha" EXACT [UniProtKB:P06865] xref: EMBL:AAA51827.1 xref: EMBL:AAB00965.1 xref: EMBL:AAD13932.1 xref: EMBL:AAH18927.1 xref: EMBL:AAH84537.1 xref: UniProtKB:P06865 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014162 ! HEXA_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000947 ! beta-N-acetylhexosaminidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0005808 ! cation binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0008814 ! usp22-hexa physical interaction [Term] id: CCO:B0043446 name: RM10_HUMAN def: "39S ribosomal protein L10, mitochondrial precursor" [UniProtKB:Q7Z7H8] synonym: "L10mt" EXACT [UniProtKB:Q7Z7H8] synonym: "MRP-L10" EXACT [UniProtKB:Q7Z7H8] synonym: "MRP-L8" EXACT [UniProtKB:Q7Z7H8] xref: EMBL:AAH15904.1 xref: EMBL:AAH52601.1 xref: EMBL:BAB54946.1 xref: UniProtKB:Q7Z7H8 xref: UniProtKB:Q96B80 xref: UniProtKB:Q96Q55 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014171 ! MRPL10_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000345 ! mitochondrial large ribosomal subunit relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0008815 ! usp22-mrpl10 physical interaction [Term] id: CCO:B0043447 name: DD19B_HUMAN def: "ATP-dependent RNA helicase DDX19B" [UniProtKB:Q9UMR2] synonym: "DEAD box protein 19B" EXACT [UniProtKB:Q9UMR2] synonym: "DEAD box RNA helicase DEAD5" EXACT [UniProtKB:Q9UMR2] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9UMR2] xref: EMBL:AAH03626.1 xref: EMBL:CAB52189.1 xref: EMBL:CAB66574.1 xref: EMBL:CAG33496.1 xref: EMBL:CAG38540.1 xref: EMBL:EAW51834.1 xref: UniProtKB:Q6FIB7 xref: UniProtKB:Q6IAE0 xref: UniProtKB:Q9H0U0 xref: UniProtKB:Q9UMR2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014154 ! DDX19B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008820 ! ddx19b-skp1a physical interaction relationship: transforms_into CCO:B0064683 ! DD19B_HUMAN-Phosphoserine86 [Term] id: CCO:B0043448 name: RT09_HUMAN def: "28S ribosomal protein S9, mitochondrial precursor" [UniProtKB:P82933] synonym: "MRP-S9" EXACT [UniProtKB:P82933] synonym: "S9mt" EXACT [UniProtKB:P82933] xref: UniProtKB:P82933 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014175 ! MRPS9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008821 ! mrps9-ccndbp1 physical interaction relationship: transforms_into CCO:B0070251 ! RT09_HUMAN-Phosphotyrosine262 [Term] id: CCO:B0043449 name: Q75LH2_HUMAN def: "Putative uncharacterized protein FLJ10324" [UniProtKB:Q75LH2] xref: EMBL:AAS07560.1 xref: UniProtKB:Q75LH2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014183 ! FLJ10324_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008822 ! psmd14-flj10324 physical interaction relationship: participates_in CCO:I0019903 ! ascc2-flj10324 physical interaction relationship: participates_in CCO:I0019997 ! fgfr3-flj10324 physical interaction relationship: participates_in CCO:I0020583 ! litaf-flj10324 physical interaction [Term] id: CCO:B0043450 name: RB15B_HUMAN def: "Putative RNA-binding protein 15B" [UniProtKB:Q8NDT2] synonym: "RNA-binding motif protein 15B" EXACT [UniProtKB:Q8NDT2] xref: EMBL:AAH01367.2 xref: EMBL:AAS50153.1 xref: EMBL:CAD38547.2 xref: UniProtKB:Q6QE19 xref: UniProtKB:Q8NDT2 xref: UniProtKB:Q9BV96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014169 ! RBM15B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008823 ! psmd14-rbm15b physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0043478 ! RB15B_HUMAN-Phosphothreonine205 relationship: transforms_into CCO:B0043479 ! RB15B_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0043480 ! RB15B_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0043481 ! RB15B_HUMAN-Phosphoserine273 relationship: transforms_into CCO:B0043482 ! RB15B_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0043483 ! RB15B_HUMAN-Phosphoserine282 relationship: transforms_into CCO:B0048371 ! RB15B_HUMAN-Phosphoserine235 [Term] id: CCO:B0043459 name: CENA1_HUMAN-Phosphoserine87 def: "Protein CENA1_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:O75689] comment: by PKC; xref: UniProtKB:O75689 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043443 ! CENA1_HUMAN [Term] id: CCO:B0043460 name: CENA1_HUMAN-Phosphothreonine276 def: "Protein CENA1_HUMAN with the residue 276 substituted with Phosphothreonine" [UniProtKB:O75689] comment: by PKC; xref: UniProtKB:O75689 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005869 ! inositol 1,3,4,5 tetrakisphosphate binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0043443 ! CENA1_HUMAN [Term] id: CCO:B0043461 name: EZH2_HUMAN-Phosphoserine380 def: "Protein EZH2_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q15910] xref: UniProtKB:Q15910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:B0043462 name: EZH2_HUMAN-Phosphothreonine487 def: "Protein EZH2_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:Q15910] xref: UniProtKB:Q15910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:B0043463 name: FBX41_HUMAN-N-acetylalanine2 def: "Protein FBX41_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q8TF61] comment: By similarity xref: UniProtKB:Q8TF61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043435 ! FBX41_HUMAN [Term] id: CCO:B0043464 name: FBX41_HUMAN-Phosphoserine3 def: "Protein FBX41_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:Q8TF61] comment: By similarity xref: UniProtKB:Q8TF61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043435 ! FBX41_HUMAN [Term] id: CCO:B0043465 name: FBX41_HUMAN-Phosphoserine21 def: "Protein FBX41_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q8TF61] comment: By similarity xref: UniProtKB:Q8TF61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043435 ! FBX41_HUMAN [Term] id: CCO:B0043466 name: FBX41_HUMAN-Phosphoserine478 def: "Protein FBX41_HUMAN with the residue 478 substituted with Phosphoserine" [UniProtKB:Q8TF61] comment: By similarity xref: UniProtKB:Q8TF61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043435 ! FBX41_HUMAN [Term] id: CCO:B0043467 name: FBX41_HUMAN-Phosphothreonine479 def: "Protein FBX41_HUMAN with the residue 479 substituted with Phosphothreonine" [UniProtKB:Q8TF61] comment: By similarity xref: UniProtKB:Q8TF61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043435 ! FBX41_HUMAN [Term] id: CCO:B0043468 name: FBX41_HUMAN-Phosphoserine547 def: "Protein FBX41_HUMAN with the residue 547 substituted with Phosphoserine" [UniProtKB:Q8TF61] comment: By similarity xref: UniProtKB:Q8TF61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043435 ! FBX41_HUMAN [Term] id: CCO:B0043469 name: FBXW8_HUMAN-Phosphoserine85 def: "Protein FBXW8_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q8N3Y1] comment: By similarity xref: UniProtKB:Q8N3Y1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043434 ! FBXW8_HUMAN [Term] id: CCO:B0043470 name: IP3KB_HUMAN-Phosphoserine43 def: "Protein IP3KB_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:P27987] xref: UniProtKB:P27987 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043425 ! IP3KB_HUMAN [Term] id: CCO:B0043471 name: IP3KB_HUMAN-Phosphoserine49 def: "Protein IP3KB_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:P27987] xref: UniProtKB:P27987 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043425 ! IP3KB_HUMAN [Term] id: CCO:B0043472 name: NCOA3_HUMAN-N6-acetyllysine616 def: "Protein NCOA3_HUMAN with the residue 616 substituted with N6-acetyllysine" [UniProtKB:Q9Y6Q9] comment: by CREBBP; xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0043473 name: NCOA3_HUMAN-N6-acetyllysine619 def: "Protein NCOA3_HUMAN with the residue 619 substituted with N6-acetyllysine" [UniProtKB:Q9Y6Q9] comment: by CREBBP; xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0043474 name: NCOA3_HUMAN-N6-acetyllysine620 def: "Protein NCOA3_HUMAN with the residue 620 substituted with N6-acetyllysine" [UniProtKB:Q9Y6Q9] comment: by CREBBP; xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0043475 name: NCOA3_HUMAN-Phosphoserine857 def: "Protein NCOA3_HUMAN with the residue 857 substituted with Phosphoserine" [UniProtKB:Q9Y6Q9] xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005585 ! nuclear hormone receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0043476 name: NCOA3_HUMAN-Phosphoserine867 def: "Protein NCOA3_HUMAN with the residue 867 substituted with Phosphoserine" [UniProtKB:Q9Y6Q9] xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0043477 name: PSME2_HUMAN-N-acetylalanine2 def: "Protein PSME2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9UL46] xref: UniProtKB:Q9UL46 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043427 ! PSME2_HUMAN [Term] id: CCO:B0043478 name: RB15B_HUMAN-Phosphothreonine205 def: "Protein RB15B_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:Q8NDT2] xref: UniProtKB:Q8NDT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:B0043479 name: RB15B_HUMAN-Phosphoserine225 def: "Protein RB15B_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q8NDT2] xref: UniProtKB:Q8NDT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:B0043480 name: RB15B_HUMAN-Phosphoserine271 def: "Protein RB15B_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q8NDT2] xref: UniProtKB:Q8NDT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:B0043481 name: RB15B_HUMAN-Phosphoserine273 def: "Protein RB15B_HUMAN with the residue 273 substituted with Phosphoserine" [UniProtKB:Q8NDT2] xref: UniProtKB:Q8NDT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:B0043482 name: RB15B_HUMAN-Phosphoserine274 def: "Protein RB15B_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q8NDT2] xref: UniProtKB:Q8NDT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:B0043483 name: RB15B_HUMAN-Phosphoserine282 def: "Protein RB15B_HUMAN with the residue 282 substituted with Phosphoserine" [UniProtKB:Q8NDT2] xref: UniProtKB:Q8NDT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:B0043484 name: RERE_HUMAN-Phosphoserine594 def: "Protein RERE_HUMAN with the residue 594 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0043485 name: RERE_HUMAN-Phosphothreonine599 def: "Protein RERE_HUMAN with the residue 599 substituted with Phosphothreonine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0043486 name: RERE_HUMAN-Phosphoserine600 def: "Protein RERE_HUMAN with the residue 600 substituted with Phosphoserine" [UniProtKB:Q9P2R6] comment: By similarity xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0043487 name: RERE_HUMAN-Phosphoserine613 def: "Protein RERE_HUMAN with the residue 613 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0043488 name: RERE_HUMAN-Phosphoserine656 def: "Protein RERE_HUMAN with the residue 656 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0043489 name: RERE_HUMAN-Phosphoserine675 def: "Protein RERE_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:Q9P2R6] comment: By similarity xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0043490 name: RERE_HUMAN-Phosphoserine679 def: "Protein RERE_HUMAN with the residue 679 substituted with Phosphoserine" [UniProtKB:Q9P2R6] comment: By similarity xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0043491 name: RSMB_HUMAN-Omega-N-methylated arginine108 def: "Protein RSMB_HUMAN with the residue 108 substituted with Omega-N-methylated arginine" [UniProtKB:P14678] xref: UniProtKB:P14678 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043440 ! RSMB_HUMAN [Term] id: CCO:B0043492 name: RSMB_HUMAN-Omega-N-methylated arginine112 def: "Protein RSMB_HUMAN with the residue 112 substituted with Omega-N-methylated arginine" [UniProtKB:P14678] xref: UniProtKB:P14678 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0043440 ! RSMB_HUMAN [Term] id: CCO:B0043493 name: TNNT1_HUMAN-N-acetylserine2 def: "Protein TNNT1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P13805] comment: By similarity xref: UniProtKB:P13805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043421 ! TNNT1_HUMAN [Term] id: CCO:B0043494 name: TNNT1_HUMAN-Phosphoserine2 def: "Protein TNNT1_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P13805] comment: by CK2; By similarity xref: UniProtKB:P13805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001654 ! tropomyosin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000424 ! troponin complex relationship: transformation_of CCO:B0043421 ! TNNT1_HUMAN [Term] id: CCO:B0043495 name: TRI39_HUMAN-Phosphotyrosine439 def: "Protein TRI39_HUMAN with the residue 439 substituted with Phosphotyrosine" [UniProtKB:Q9HCM9] xref: UniProtKB:Q9HCM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0043417 ! TRI39_HUMAN [Term] id: CCO:B0043496 name: VINC_HUMAN-Phosphoserine290 def: "Protein VINC_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:P18206] xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043497 name: VINC_HUMAN-Phosphothreonine324 def: "Protein VINC_HUMAN with the residue 324 substituted with Phosphothreonine" [UniProtKB:P18206] comment: By similarity xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006102 ! alpha-catenin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000464 ! adherens junction relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001711 ! costamere relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002136 ! cell-substrate junction relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043498 name: VINC_HUMAN-Phosphothreonine508 def: "Protein VINC_HUMAN with the residue 508 substituted with Phosphothreonine" [UniProtKB:P18206] xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043499 name: VINC_HUMAN-Phosphotyrosine537 def: "Protein VINC_HUMAN with the residue 537 substituted with Phosphotyrosine" [UniProtKB:P18206] comment: Potential xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043500 name: VINC_HUMAN-Phosphothreonine604 def: "Protein VINC_HUMAN with the residue 604 substituted with Phosphothreonine" [UniProtKB:P18206] xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043501 name: VINC_HUMAN-Phosphoserine721 def: "Protein VINC_HUMAN with the residue 721 substituted with Phosphoserine" [UniProtKB:P18206] xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043502 name: VINC_HUMAN-Phosphoserine774 def: "Protein VINC_HUMAN with the residue 774 substituted with Phosphoserine" [UniProtKB:P18206] comment: By similarity xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043503 name: VINC_HUMAN-Phosphotyrosine822 def: "Protein VINC_HUMAN with the residue 822 substituted with Phosphotyrosine" [UniProtKB:P18206] xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0043504 name: XRN2_HUMAN-Phosphoserine448 def: "Protein XRN2_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:Q9H0D6] xref: UniProtKB:Q9H0D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:B0043505 name: XRN2_HUMAN-Phosphoserine455 def: "Protein XRN2_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q9H0D6] xref: UniProtKB:Q9H0D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:B0043506 name: XRN2_HUMAN-Phosphoserine499 def: "Protein XRN2_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:Q9H0D6] xref: UniProtKB:Q9H0D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:B0043507 name: XRN2_HUMAN-Phosphoserine501 def: "Protein XRN2_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q9H0D6] xref: UniProtKB:Q9H0D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0000930 ! 5'-3' exoribonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001876 ! 5'-3' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:B0043520 name: CXA1_HUMAN def: "Gap junction alpha-1 protein" [UniProtKB:P17302] synonym: "Connexin-43" EXACT [UniProtKB:P17302] synonym: "Cx43" EXACT [UniProtKB:P17302] synonym: "Gap junction 43 kDa heart protein" EXACT [UniProtKB:P17302] xref: EMBL:AAA52131.1 xref: EMBL:AAD37802.2 xref: EMBL:AAH26329.1 xref: EMBL:CAA37122.1 xref: EMBL:CAG46461.1 xref: EMBL:CAI20002.1 xref: EMBL:EAW48178.1 xref: UniProtKB:P17302 xref: UniProtKB:Q6FHU1 xref: UniProtKB:Q9Y5I8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014220 ! GJA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018755 ! zo_1-cx43 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0043772 ! CXA1_HUMAN-Phosphotyrosine247 relationship: transforms_into CCO:B0043773 ! CXA1_HUMAN-Phosphoserine262 relationship: transforms_into CCO:B0043774 ! CXA1_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0043775 ! CXA1_HUMAN-Phosphotyrosine313 relationship: transforms_into CCO:B0043776 ! CXA1_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: transforms_into CCO:B0043778 ! CXA1_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0043779 ! CXA1_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0052349 ! CXA1_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0052350 ! CXA1_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0052351 ! CXA1_HUMAN-Phosphoserine369 relationship: transforms_into CCO:B0052352 ! CXA1_HUMAN-Phosphoserine373 [Term] id: CCO:B0043529 name: SPSB3_HUMAN def: "SPRY domain-containing SOCS box protein 3" [UniProtKB:Q6PJ21] synonym: "SSB-3" EXACT [UniProtKB:Q6PJ21] xref: EMBL:AAH07588.2 xref: EMBL:AAH24244.1 xref: EMBL:AAH41897.1 xref: EMBL:AAH47441.2 xref: EMBL:AAK61293.1 xref: EMBL:AAL57347.1 xref: UniProtKB:Q49A96 xref: UniProtKB:Q6PJ21 xref: UniProtKB:Q86X18 xref: UniProtKB:Q8WXK5 xref: UniProtKB:Q96IE6 xref: UniProtKB:Q96RY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014246 ! SPSB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0043530 name: Q96LS6_HUMAN def: "CDNA FLJ25121 fis, clone CBR06051 (SplA/ryanodine receptor domain and SOCS box containing 3, isoform CRA_c)" [UniProtKB:Q96LS6] xref: EMBL:BAB71594.1 xref: EMBL:EAW85621.1 xref: UniProtKB:Q96LS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014246 ! SPSB3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0043535 name: UB2E3_HUMAN def: "Ubiquitin-conjugating enzyme E2 E3" [UniProtKB:Q969T4] synonym: "EC 6.3.2.19" EXACT [UniProtKB:Q969T4] synonym: "UbcH9" EXACT [UniProtKB:Q969T4] synonym: "UbcM2" EXACT [UniProtKB:Q969T4] synonym: "Ubiquitin carrier protein E3" EXACT [UniProtKB:Q969T4] synonym: "Ubiquitin-conjugating enzyme E2-23 kDa" EXACT [UniProtKB:Q969T4] synonym: "Ubiquitin-protein ligase E3" EXACT [UniProtKB:Q969T4] xref: EMBL:AAD40197.1 xref: EMBL:AAH03554.1 xref: EMBL:AAH92407.1 xref: EMBL:AAP97266.1 xref: EMBL:AAV38152.1 xref: EMBL:AAY14882.1 xref: EMBL:BAA76544.1 xref: UniProtKB:Q5U0R7 xref: UniProtKB:Q7Z4W4 xref: UniProtKB:Q969T4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014250 ! UBE2E3_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018445 ! hsrma1-ubch9 physical interaction relationship: participates_in CCO:I0019011 ! atxn1-ube2e3 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0043795 ! UB2E3_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0043796 ! UB2E3_HUMAN-Phosphotyrosine91 [Term] id: CCO:B0043543 name: JHD1B_HUMAN def: "JmjC domain-containing histone demethylation protein 1B" [UniProtKB:Q8NHM5] synonym: "[Histone-H3]-lysine-36 demethylase 1B" EXACT [UniProtKB:Q8NHM5] synonym: "CXXC-type zinc finger protein 2" EXACT [UniProtKB:Q8NHM5] synonym: "EC 1.14.11.27" EXACT [UniProtKB:Q8NHM5] synonym: "F-box and leucine-rich repeat protein 10" EXACT [UniProtKB:Q8NHM5] synonym: "F-box protein FBL10" EXACT [UniProtKB:Q8NHM5] synonym: "F-box/LRR-repeat protein 10" EXACT [UniProtKB:Q8NHM5] synonym: "Jumonji domain-containing EMSY-interactor methyltransferase motif protein" EXACT [UniProtKB:Q8NHM5] synonym: "Protein JEMMA" EXACT [UniProtKB:Q8NHM5] synonym: "Protein-containing CXXC domain 2" EXACT [UniProtKB:Q8NHM5] xref: EMBL:AAH08735.2 xref: EMBL:BAA97672.1 xref: EMBL:BAB55112.1 xref: EMBL:BAB55301.1 xref: EMBL:BAC11159.1 xref: EMBL:CAB63721.2 xref: EMBL:CAD30700.1 xref: UniProtKB:Q8NCI2 xref: UniProtKB:Q8NHM5 xref: UniProtKB:Q96HC7 xref: UniProtKB:Q96SL0 xref: UniProtKB:Q96T03 xref: UniProtKB:Q9NS96 xref: UniProtKB:Q9UF75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014237 ! FBXL10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0043783 ! JHD1B_HUMAN-Phosphotyrosine223 relationship: transforms_into CCO:B0043784 ! JHD1B_HUMAN-Phosphoserine474 relationship: transforms_into CCO:B0043785 ! JHD1B_HUMAN-Phosphoserine497 [Term] id: CCO:B0043552 name: PI51A_HUMAN def: "Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha" [UniProtKB:Q99755] synonym: "68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha" EXACT [UniProtKB:Q99755] synonym: "EC 2.7.1.68" EXACT [UniProtKB:Q99755] synonym: "Phosphatidylinositol-4-phosphate 5-kinase type I alpha" EXACT [UniProtKB:Q99755] synonym: "PIP5KIalpha" EXACT [UniProtKB:Q99755] synonym: "PtdIns(4)P-5-kinase alpha" EXACT [UniProtKB:Q99755] xref: EMBL:AAC50910.1 xref: EMBL:AAC50911.1 xref: EMBL:AAC50912.1 xref: EMBL:AAH07833.1 xref: EMBL:CAI16386.1 xref: EMBL:CAI16387.1 xref: EMBL:CAI16388.1 xref: UniProtKB:Q99754 xref: UniProtKB:Q99755 xref: UniProtKB:Q99756 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014239 ! PIP5K1A_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003116 ! phosphatidylinositol phosphate kinase activity relationship: has_function CCO:F0003117 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0043592 name: RL23_HUMAN def: "60S ribosomal protein L23" [UniProtKB:P62829] synonym: "Ribosomal protein L17" EXACT [UniProtKB:P62829] xref: EMBL:AAH10114.1 xref: EMBL:AAH62716.1 xref: EMBL:AAI04652.1 xref: EMBL:AAI06062.1 xref: EMBL:BAB79465.1 xref: EMBL:CAA37023.1 xref: EMBL:CAA39417.1 xref: UniProtKB:P23131 xref: UniProtKB:P24048 xref: UniProtKB:P62829 xref: UniProtKB:Q29246 xref: UniProtKB:Q3SWV7 xref: UniProtKB:Q6P5S1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014242 ! RPL23_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016374 ! nfkbia-rpl23 physical interaction relationship: participates_in CCO:I0016505 ! ikbkg-rpl23 physical interaction relationship: participates_in CCO:I0016682 ! map3k3-rpl23 physical interaction relationship: participates_in CCO:I0016897 ! ripk1-rpl23 physical interaction relationship: participates_in CCO:I0016941 ! q9nyj8-rpl23 physical interaction relationship: participates_in CCO:I0016993 ! tnfrsf1a-rpl23 physical interaction relationship: participates_in CCO:I0017119 ! traf2-rpl23 physical interaction relationship: transforms_into CCO:B0043789 ! RL23_HUMAN-Phosphotyrosine38 [Term] id: CCO:B0043602 name: LRC41_HUMAN def: "Leucine-rich repeat-containing protein 41" [UniProtKB:Q15345] synonym: "Protein Muf1" EXACT [UniProtKB:Q15345] xref: EMBL:AAH04953.2 xref: EMBL:AAI01523.1 xref: EMBL:AAI01525.1 xref: EMBL:AAQ15266.1 xref: EMBL:BAC86308.1 xref: EMBL:CAA60013.1 xref: EMBL:CAD97609.1 xref: EMBL:CAI21964.1 xref: EMBL:CAI22118.1 xref: UniProtKB:Q15345 xref: UniProtKB:Q3MJ96 xref: UniProtKB:Q5TDF5 xref: UniProtKB:Q71RA8 xref: UniProtKB:Q9BSM0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014238 ! LRRC41_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020376 ! muf1-myo9b physical interaction relationship: transforms_into CCO:B0043786 ! LRC41_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0043787 ! LRC41_HUMAN-Phosphothreonine327 relationship: transforms_into CCO:B0067771 ! LRC41_HUMAN-Phosphoserine357 [Term] id: CCO:B0043604 name: DEDD_HUMAN def: "Death effector domain-containing protein" [UniProtKB:O75618] synonym: "Death effector domain-containing testicular molecule" EXACT [UniProtKB:O75618] synonym: "DEDPro1" EXACT [UniProtKB:O75618] synonym: "FLDED-1" EXACT [UniProtKB:O75618] xref: EMBL:AAC17110.3 xref: EMBL:AAC33105.1 xref: EMBL:AAC80280.1 xref: EMBL:AAD16414.1 xref: EMBL:AAH13910.1 xref: EMBL:AAH16724.1 xref: EMBL:CAA09445.1 xref: EMBL:CAG38793.1 xref: EMBL:CAI15381.1 xref: UniProtKB:O60737 xref: UniProtKB:O75618 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014230 ! DEDD_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0043605 name: DEDD2_HUMAN def: "DNA-binding death effector domain-containing protein 2" [UniProtKB:Q8WXF8] synonym: "DED-containing protein FLAME-3" EXACT [UniProtKB:Q8WXF8] synonym: "FADD-like anti-apoptotic molecule 3" EXACT [UniProtKB:Q8WXF8] xref: EMBL:AAH13372.2 xref: EMBL:AAH27930.1 xref: EMBL:AAL48220.1 xref: EMBL:AAM10835.1 xref: EMBL:AAM95240.1 xref: EMBL:BAC11551.1 xref: UniProtKB:Q8NBR2 xref: UniProtKB:Q8NES1 xref: UniProtKB:Q8TAA8 xref: UniProtKB:Q8WXF8 xref: UniProtKB:Q96D35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014229 ! DEDD2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001250 ! apoptotic nuclear changes relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0043606 name: B1AQP5_HUMAN def: "Death effector domain containing (Death effector domain containing, isoform CRA_b)" [UniProtKB:B1AQP5] xref: EMBL:CAI15382.1 xref: EMBL:EAW52649.1 xref: UniProtKB:B1AQP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014230 ! DEDD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0043610 name: F16P1_HUMAN def: "Fructose-1,6-bisphosphatase 1" [UniProtKB:P09467] synonym: "D-fructose-1,6-bisphosphate 1-phosphohydrolase 1" EXACT [UniProtKB:P09467] synonym: "EC 3.1.3.11" EXACT [UniProtKB:P09467] synonym: "FBPase 1" EXACT [UniProtKB:P09467] xref: EMBL:AAA35517.1 xref: EMBL:AAA35817.1 xref: EMBL:AAA89097.1 xref: EMBL:AAA89098.1 xref: EMBL:AAC25774.1 xref: EMBL:AAC50207.1 xref: EMBL:AAH12927.1 xref: EMBL:AAW34363.1 xref: EMBL:BAA05051.1 xref: EMBL:BAA05052.1 xref: EMBL:BAA05053.1 xref: EMBL:BAD97115.1 xref: EMBL:CAH72692.1 xref: UniProtKB:O75571 xref: UniProtKB:P09467 xref: UniProtKB:Q53F94 xref: UniProtKB:Q96E46 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014234 ! FBP1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000750 ! fructose-2,6-bisphosphate 2-phosphatase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005685 ! phosphoric ester hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008485 ! fructose 1,6-bisphosphate 1-phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0019661 ! ascc2-fbp1 physical interaction [Term] id: CCO:B0043612 name: F16P2_HUMAN def: "Fructose-1,6-bisphosphatase isozyme 2" [UniProtKB:O00757] synonym: "D-fructose-1,6-bisphosphate 1-phosphohydrolase 2" EXACT [UniProtKB:O00757] synonym: "EC 3.1.3.11" EXACT [UniProtKB:O00757] synonym: "FBPase 2" EXACT [UniProtKB:O00757] xref: EMBL:AAI13633.1 xref: EMBL:AAI17478.1 xref: EMBL:CAA71772.1 xref: EMBL:CAG38722.1 xref: EMBL:CAH72694.1 xref: UniProtKB:O00757 xref: UniProtKB:Q17R39 xref: UniProtKB:Q6FI53 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014235 ! FBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020309 ! fbp2-chd3 physical interaction relationship: transforms_into CCO:B0066061 ! F16P2_HUMAN-Phosphotyrosine216 [Term] id: CCO:B0043706 name: SPSB4_HUMAN def: "SPRY domain-containing SOCS box protein 4" [UniProtKB:Q96A44] synonym: "SSB-4" EXACT [UniProtKB:Q96A44] xref: EMBL:AAH08324.1 xref: EMBL:AAL57348.1 xref: EMBL:BAB71165.1 xref: UniProtKB:Q96A44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014247 ! SPSB4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0043707 name: SPSB2_HUMAN def: "SPRY domain-containing SOCS box protein 2" [UniProtKB:Q99619] synonym: "Gene-rich cluster protein C9" EXACT [UniProtKB:Q99619] synonym: "SSB-2" EXACT [UniProtKB:Q99619] xref: EMBL:AAB51328.1 xref: EMBL:AAH02983.1 xref: EMBL:AAH71933.1 xref: EMBL:AAL57346.1 xref: UniProtKB:Q99619 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014245 ! SPSB2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0043708 name: SPSB1_HUMAN def: "SPRY domain-containing SOCS box protein 1" [UniProtKB:Q96BD6] synonym: "SSB-1" EXACT [UniProtKB:Q96BD6] xref: EMBL:AAH05852.2 xref: EMBL:AAH15711.1 xref: EMBL:AAL57345.1 xref: EMBL:BAB15335.1 xref: EMBL:BAD92796.1 xref: EMBL:CAI14376.2 xref: EMBL:CAM12843.1 xref: EMBL:EAW71617.1 xref: UniProtKB:A2A275 xref: UniProtKB:Q59FA1 xref: UniProtKB:Q5TIH9 xref: UniProtKB:Q96BD6 xref: UniProtKB:Q9BRY9 xref: UniProtKB:Q9H6C5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014244 ! SPSB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0043791 ! SPSB1_HUMAN-Phosphotyrosine31 [Term] id: CCO:B0043733 name: TTF1_HUMAN def: "Transcription termination factor 1" [UniProtKB:Q15361] synonym: "RNA polymerase I termination factor" EXACT [UniProtKB:Q15361] synonym: "TTF-1" EXACT [UniProtKB:Q15361] synonym: "TTF-I" EXACT [UniProtKB:Q15361] xref: EMBL:AAH50734.1 xref: EMBL:AAH62692.1 xref: EMBL:AAI04640.1 xref: EMBL:AAI27670.1 xref: EMBL:AAI27671.1 xref: EMBL:AAI43049.1 xref: EMBL:AAI43050.1 xref: EMBL:CAA58807.1 xref: EMBL:CAI94997.2 xref: UniProtKB:A1L160 xref: UniProtKB:Q15361 xref: UniProtKB:Q4VXF3 xref: UniProtKB:Q58EY2 xref: UniProtKB:Q6P5T5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014248 ! TTF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0043792 ! TTF1_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0043793 ! TTF1_HUMAN-Phosphoserine487 relationship: transforms_into CCO:B0043794 ! TTF1_HUMAN-Phosphoserine872 relationship: transforms_into CCO:B0071619 ! TTF1_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0071620 ! TTF1_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0071621 ! TTF1_HUMAN-Phosphoserine478 relationship: transforms_into CCO:B0071622 ! TTF1_HUMAN-Phosphoserine481 [Term] id: CCO:B0043772 name: CXA1_HUMAN-Phosphotyrosine247 def: "Protein CXA1_HUMAN with the residue 247 substituted with Phosphotyrosine" [UniProtKB:P17302] xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043773 name: CXA1_HUMAN-Phosphoserine262 def: "Protein CXA1_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:P17302] xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043774 name: CXA1_HUMAN-Phosphoserine306 def: "Protein CXA1_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043775 name: CXA1_HUMAN-Phosphotyrosine313 def: "Protein CXA1_HUMAN with the residue 313 substituted with Phosphotyrosine" [UniProtKB:P17302] xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043776 name: CXA1_HUMAN-Phosphoserine314 def: "Protein CXA1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043777 name: CXA1_HUMAN-Phosphothreonine326 def: "Protein CXA1_HUMAN with the residue 326 substituted with Phosphothreonine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001511 ! gap junction channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002557 ! ion transmembrane transporter activity relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000354 ! multivesicular body relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000468 ! fascia adherens relationship: located_in CCO:C0000473 ! gap junction relationship: located_in CCO:C0000474 ! connexon complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001025 ! Golgi-associated vesicle membrane relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043778 name: CXA1_HUMAN-Phosphoserine328 def: "Protein CXA1_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043779 name: CXA1_HUMAN-Phosphoserine330 def: "Protein CXA1_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0043783 name: JHD1B_HUMAN-Phosphotyrosine223 def: "Protein JHD1B_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:Q8NHM5] xref: UniProtKB:Q8NHM5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043543 ! JHD1B_HUMAN [Term] id: CCO:B0043784 name: JHD1B_HUMAN-Phosphoserine474 def: "Protein JHD1B_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:Q8NHM5] xref: UniProtKB:Q8NHM5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043543 ! JHD1B_HUMAN [Term] id: CCO:B0043785 name: JHD1B_HUMAN-Phosphoserine497 def: "Protein JHD1B_HUMAN with the residue 497 substituted with Phosphoserine" [UniProtKB:Q8NHM5] xref: UniProtKB:Q8NHM5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008199 ! histone demethylase activity (H3-K36 specific) relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0043543 ! JHD1B_HUMAN [Term] id: CCO:B0043786 name: LRC41_HUMAN-Phosphoserine276 def: "Protein LRC41_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q15345] xref: UniProtKB:Q15345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043602 ! LRC41_HUMAN [Term] id: CCO:B0043787 name: LRC41_HUMAN-Phosphothreonine327 def: "Protein LRC41_HUMAN with the residue 327 substituted with Phosphothreonine" [UniProtKB:Q15345] xref: UniProtKB:Q15345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043602 ! LRC41_HUMAN [Term] id: CCO:B0043789 name: RL23_HUMAN-Phosphotyrosine38 def: "Protein RL23_HUMAN with the residue 38 substituted with Phosphotyrosine" [UniProtKB:P62829] xref: UniProtKB:P62829 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:B0043790 name: S10A4_HUMAN-N-acetylalanine2 def: "Protein S10A4_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P26447] comment: By similarity xref: UniProtKB:P26447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019310 ! S10A4_HUMAN [Term] id: CCO:B0043791 name: SPSB1_HUMAN-Phosphotyrosine31 def: "Protein SPSB1_HUMAN with the residue 31 substituted with Phosphotyrosine" [UniProtKB:Q96BD6] comment: by MET; xref: UniProtKB:Q96BD6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043708 ! SPSB1_HUMAN [Term] id: CCO:B0043792 name: TTF1_HUMAN-Phosphoserine240 def: "Protein TTF1_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q15361] xref: UniProtKB:Q15361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000302 ! transcription termination factor activity relationship: has_function CCO:F0000303 ! RNA polymerase I transcription termination factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0043733 ! TTF1_HUMAN [Term] id: CCO:B0043793 name: TTF1_HUMAN-Phosphoserine487 def: "Protein TTF1_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:Q15361] xref: UniProtKB:Q15361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043733 ! TTF1_HUMAN [Term] id: CCO:B0043794 name: TTF1_HUMAN-Phosphoserine872 def: "Protein TTF1_HUMAN with the residue 872 substituted with Phosphoserine" [UniProtKB:Q15361] xref: UniProtKB:Q15361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043733 ! TTF1_HUMAN [Term] id: CCO:B0043795 name: UB2E3_HUMAN-Phosphoserine12 def: "Protein UB2E3_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q969T4] xref: UniProtKB:Q969T4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043535 ! UB2E3_HUMAN [Term] id: CCO:B0043796 name: UB2E3_HUMAN-Phosphotyrosine91 def: "Protein UB2E3_HUMAN with the residue 91 substituted with Phosphotyrosine" [UniProtKB:Q969T4] comment: By similarity xref: UniProtKB:Q969T4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043535 ! UB2E3_HUMAN [Term] id: CCO:B0043816 name: ZBT7C_HUMAN def: "Zinc finger and BTB domain-containing protein 7C" [UniProtKB:A1YPR0] synonym: "Affected by papillomavirus DNA integration in ME180 cells protein 1" EXACT [UniProtKB:A1YPR0] synonym: "APM-1" EXACT [UniProtKB:A1YPR0] synonym: "Zinc finger and BTB domain-containing protein 36" EXACT [UniProtKB:A1YPR0] xref: EMBL:ABL98073.1 xref: EMBL:CAA74933.1 xref: UniProtKB:A1YPR0 xref: UniProtKB:O73453 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014370 ! ZBTB7C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle relationship: transforms_into CCO:B0071980 ! ZBT7C_HUMAN-Phosphotyrosine331 [Term] id: CCO:B0043817 name: NGX6_HUMAN def: "Protein NGX6" [UniProtKB:A6NDV4] synonym: "Nasopharyngeal carcinoma-associated gene 6 protein" EXACT [UniProtKB:A6NDV4] synonym: "Protein NAG-5" EXACT [UniProtKB:A6NDV4] xref: EMBL:AAC28644.1 xref: EMBL:AAF34820.1 xref: EMBL:AAG29055.1 xref: EMBL:AAH41377.1 xref: EMBL:AAH98265.1 xref: EMBL:AAH98296.1 xref: EMBL:AAH99733.1 xref: EMBL:CAI10995.1 xref: EMBL:CAI10996.2 xref: EMBL:EAW58325.1 xref: UniProtKB:A6NDV4 xref: UniProtKB:O75539 xref: UniProtKB:Q49AB1 xref: UniProtKB:Q4KMX5 xref: UniProtKB:Q5TCW5 xref: UniProtKB:Q9HBY2 xref: UniProtKB:Q9P0U7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014360 ! C9orf127_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000138 ! regulation of mitotic cell cycle relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0043818 name: MERP_HUMAN def: "Meiosis-related protein" [UniProtKB:A8MT33] xref: UniProtKB:A6NF23 xref: UniProtKB:A8MT33 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0043819 name: B2D1N3_HUMAN def: "Cyclin-dependent kinase inhibitor 1C transcript variant 3" [UniProtKB:B2D1N3] xref: EMBL:ACB69757.1 xref: UniProtKB:B2D1N3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004311 ! CDKN1C_human relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0006166 ! nutrient reservoir activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000067 ! cell cycle arrest [Term] id: CCO:B0043820 name: AIM2_HUMAN def: "Interferon-inducible protein AIM2" [UniProtKB:O14862] synonym: "Absent in melanoma 2" EXACT [UniProtKB:O14862] xref: EMBL:AAB81613.1 xref: EMBL:AAH10940.1 xref: EMBL:BAF84731.1 xref: EMBL:CAI15088.1 xref: UniProtKB:A8K7M7 xref: UniProtKB:O14862 xref: UniProtKB:Q5T3V9 xref: UniProtKB:Q96FG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014341 ! AIM2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0043821 name: IGF1B_HUMAN def: "Insulin-like growth factor IB precursor" [UniProtKB:P05019] synonym: "IGF-IB" EXACT [UniProtKB:P05019] synonym: "Mechano growth factor" EXACT [UniProtKB:P05019] synonym: "MGF" EXACT [UniProtKB:P05019] synonym: "Somatomedin-C" EXACT [UniProtKB:P05019] xref: EMBL:AAA52537.1 xref: EMBL:AAA52539.1 xref: EMBL:CAA27152.1 xref: EMBL:CAA27153.1 xref: EMBL:CAA27154.1 xref: EMBL:CAA27250.1 xref: EMBL:CAA40093.1 xref: UniProtKB:P05019 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014356 ! IGF1_human relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000829 ! insulin-like growth factor binding protein complex relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001084 ! phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001093 ! satellite cell maintenance involved in skeletal muscle regeneration relationship: participates_in CCO:P0001108 ! positive regulation of smooth muscle cell migration relationship: participates_in CCO:P0001970 ! negative regulation of smooth muscle cell apoptosis relationship: participates_in CCO:P0002088 ! positive regulation of tyrosine phosphorylation of Stat5 protein relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002246 ! positive regulation of insulin-like growth factor receptor signaling pathway relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002569 ! positive regulation of glycolysis relationship: participates_in CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: participates_in CCO:P0003091 ! myoblast proliferation [Term] id: CCO:B0043822 name: EDN1_HUMAN def: "Endothelin-1 precursor" [UniProtKB:P05305] synonym: "PPET1" EXACT [UniProtKB:P05305] synonym: "Preproendothelin-1" EXACT [UniProtKB:P05305] xref: EMBL:AAA52338.1 xref: EMBL:AAA52339.1 xref: EMBL:AAA52407.1 xref: EMBL:AAB25760.1 xref: EMBL:AAH09720.1 xref: EMBL:AAQ96600.1 xref: EMBL:CAA68718.1 xref: EMBL:CAB10846.1 xref: UniProtKB:P05305 xref: UniProtKB:Q96DA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014345 ! EDN1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0004720 ! endothelin A receptor binding relationship: has_function CCO:F0004721 ! endothelin B receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0008967 ! edn1-ubqln4 physical interaction relationship: participates_in CCO:I0008983 ! edn1-cops6 physical interaction relationship: participates_in CCO:I0008984 ! edn1-bat3 physical interaction relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001084 ! phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0001311 ! negative regulation of cAMP biosynthetic process relationship: participates_in CCO:P0001469 ! G-protein signaling, phospholipase D activating pathway relationship: participates_in CCO:P0002056 ! protein kinase C deactivation relationship: participates_in CCO:P0002170 ! rhythmic excitation relationship: participates_in CCO:P0002747 ! positive regulation of hormone secretion relationship: participates_in CCO:P0002748 ! negative regulation of hormone secretion relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0003100 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0043823 name: EDN3_HUMAN def: "Endothelin-3 precursor" [UniProtKB:P14138] synonym: "ET-3" EXACT [UniProtKB:P14138] synonym: "PPET3" EXACT [UniProtKB:P14138] synonym: "Preproendothelin-3" EXACT [UniProtKB:P14138] xref: EMBL:AAA52405.1 xref: EMBL:AAH08876.1 xref: EMBL:AAP35748.1 xref: EMBL:AAR16083.1 xref: EMBL:CAA36252.1 xref: EMBL:CAB65996.1 xref: EMBL:CAB65998.1 xref: UniProtKB:P14138 xref: UniProtKB:Q03229 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014346 ! EDN3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000251 ! positive regulation of mitosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002747 ! positive regulation of hormone secretion [Term] id: CCO:B0043824 name: IL12B_HUMAN def: "Interleukin-12 subunit beta precursor" [UniProtKB:P29460] synonym: "CLMF p40" EXACT [UniProtKB:P29460] synonym: "Cytotoxic lymphocyte maturation factor 40 kDa subunit" EXACT [UniProtKB:P29460] synonym: "IL-12 subunit p40" EXACT [UniProtKB:P29460] synonym: "IL-12B" EXACT [UniProtKB:P29460] synonym: "NK cell stimulatory factor chain 2" EXACT [UniProtKB:P29460] synonym: "NKSF2" EXACT [UniProtKB:P29460] xref: EMBL:AAA35695.1 xref: EMBL:AAA59938.1 xref: EMBL:AAD56386.1 xref: EMBL:AAG32620.1 xref: EMBL:AAH67498.1 xref: EMBL:AAH67499.1 xref: EMBL:AAH67500.1 xref: EMBL:AAH67501.1 xref: EMBL:AAH67502.1 xref: EMBL:AAH74723.1 xref: EMBL:AAM34792.1 xref: UniProtKB:P29460 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014357 ! IL12B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001445 ! interleukin-12 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005632 ! interleukin-12 alpha subunit binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001780 ! interleukin-12 complex relationship: participates_in CCO:I0008981 ! il12a-il12b-1 direct interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000605 ! positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001658 ! positive regulation of natural killer cell activation relationship: participates_in CCO:P0001971 ! positive regulation of smooth muscle cell apoptosis relationship: participates_in CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: participates_in CCO:P0002043 ! positive regulation of activated T cell proliferation relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0002915 ! positive regulation of lymphocyte proliferation [Term] id: CCO:B0043825 name: RS15A_HUMAN def: "40S ribosomal protein S15a" [UniProtKB:P62244] xref: EMBL:AAH01697.1 xref: EMBL:AAH30569.1 xref: EMBL:AAH46113.1 xref: EMBL:AAI05274.1 xref: EMBL:AAI05293.1 xref: EMBL:AAO48936.1 xref: EMBL:BAA28592.1 xref: EMBL:BAB93487.1 xref: EMBL:CAA44568.1 xref: EMBL:CAA59127.1 xref: UniProtKB:P39027 xref: UniProtKB:P39031 xref: UniProtKB:P62244 xref: UniProtKB:Q3MHD9 xref: UniProtKB:Q8C023 xref: UniProtKB:Q9BV24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014362 ! RPS15A_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0008959 ! ewsr1-rps15a physical interaction relationship: participates_in CCO:I0008960 ! elf5-rps15a physical interaction relationship: participates_in CCO:I0008963 ! ikbkg-rps15a physical interaction relationship: participates_in CCO:I0008964 ! nfkb2-rps15a physical interaction relationship: participates_in CCO:I0008965 ! map3k14-rps15a physical interaction relationship: participates_in CCO:I0008980 ! bat1-rps15a physical interaction relationship: participates_in CCO:P0000247 ! positive regulation of cell cycle relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0043826 name: SMAD3_HUMAN def: "Mothers against decapentaplegic homolog 3" [UniProtKB:P84022] synonym: "hMAD-3" EXACT [UniProtKB:P84022] synonym: "hSMAD3" EXACT [UniProtKB:P84022] synonym: "JV15-2" EXACT [UniProtKB:P84022] synonym: "Mad3" EXACT [UniProtKB:P84022] synonym: "Mothers against DPP homolog 3" EXACT [UniProtKB:P84022] synonym: "SMAD 3" EXACT [UniProtKB:P84022] xref: EMBL:AAB18967.1 xref: EMBL:AAB80960.1 xref: EMBL:AAH50743.1 xref: EMBL:AAL68976.1 xref: EMBL:BAA22032.1 xref: UniProtKB:O09064 xref: UniProtKB:O09144 xref: UniProtKB:O14510 xref: UniProtKB:O35273 xref: UniProtKB:P84022 xref: UniProtKB:Q92940 xref: UniProtKB:Q93002 xref: UniProtKB:Q9GKR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014366 ! SMAD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008961 ! smad3-zfyve9-1 direct interaction relationship: participates_in CCO:I0008962 ! smad3-sry-3 physical interaction relationship: participates_in CCO:I0008968 ! smad3-sry physical interaction relationship: participates_in CCO:I0008969 ! smad3-sry-2 physical interaction relationship: participates_in CCO:I0008970 ! smad3-actb physical interaction relationship: participates_in CCO:I0008971 ! smad-actb-2 physical interaction relationship: participates_in CCO:I0008972 ! smad3-prtn3 physical interaction relationship: participates_in CCO:I0008973 ! smad3-prtn3-2 physical interaction relationship: participates_in CCO:I0008974 ! smad3-actb-2 physical interaction relationship: participates_in CCO:I0008975 ! smad3-srebf2 physical interaction relationship: participates_in CCO:I0008976 ! smad3-srebf2-1 physical interaction relationship: participates_in CCO:I0008977 ! smad3-srebf2-2 physical interaction relationship: participates_in CCO:I0008978 ! ski-madh3-1 physical interaction relationship: participates_in CCO:I0008979 ! dach- madh3-1 physical interaction relationship: participates_in CCO:I0008982 ! smad3-smad4-1 direct interaction relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: participates_in CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000723 ! SMAD protein complex assembly relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0048394 ! SMAD3_HUMAN-Phosphoserine423 relationship: transforms_into CCO:B0048395 ! SMAD3_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 [Term] id: CCO:B0043827 name: HHEX_HUMAN def: "Hematopoietically-expressed homeobox protein HHEX" [UniProtKB:Q03014] synonym: "Homeobox protein HEX" EXACT [UniProtKB:Q03014] synonym: "Homeobox protein PRH" EXACT [UniProtKB:Q03014] xref: EMBL:AAA02988.1 xref: EMBL:AAH14336.1 xref: EMBL:AAH15110.1 xref: EMBL:AAH50638.1 xref: EMBL:CAA47661.1 xref: EMBL:CAA79730.1 xref: UniProtKB:Q03014 xref: UniProtKB:Q96CE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014349 ! HHEX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001770 ! eukaryotic initiation factor 4E binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000981 ! negative regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001248 ! positive regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0001355 ! negative regulation of vascular endothelial growth factor receptor signaling pathway relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0043828 name: IFIX_HUMAN def: "Pyrin and HIN domain-containing protein 1" [UniProtKB:Q6K0P9] synonym: "Interferon-inducible protein X" EXACT [UniProtKB:Q6K0P9] xref: EMBL:AAH20822.1 xref: EMBL:AAH90944.1 xref: EMBL:AAI39742.1 xref: EMBL:AAO67506.1 xref: EMBL:AAO67507.1 xref: EMBL:AAO67508.1 xref: EMBL:AAO67509.1 xref: EMBL:CAI15075.1 xref: EMBL:CAI15076.1 xref: EMBL:CAI15077.1 xref: EMBL:CAI15078.1 xref: EMBL:CAI15079.1 xref: EMBL:CAI15080.1 xref: EMBL:EAW52805.1 xref: UniProtKB:Q5T3W6 xref: UniProtKB:Q6K0P6 xref: UniProtKB:Q6K0P7 xref: UniProtKB:Q6K0P8 xref: UniProtKB:Q6K0P9 xref: UniProtKB:Q8WW65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014355 ! PYHIN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0043829 name: PSRC1_HUMAN def: "Proline/serine-rich coiled-coil protein 1" [UniProtKB:Q6PGN9] xref: EMBL:AAH56909.1 xref: EMBL:AAN73431.1 xref: EMBL:AAN73434.1 xref: EMBL:AAQ04649.1 xref: EMBL:BAC86599.1 xref: EMBL:CAI13172.1 xref: EMBL:CAI13173.1 xref: UniProtKB:Q6PGN9 xref: UniProtKB:Q6ZTI8 xref: UniProtKB:Q71MG3 xref: UniProtKB:Q9BV77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014361 ! PSRC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: transforms_into CCO:B0048359 ! PSRC1_HUMAN-Phosphoserine70 relationship: transforms_into CCO:B0048360 ! PSRC1_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0048361 ! PSRC1_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0048362 ! PSRC1_HUMAN-Phosphothreonine245 relationship: transforms_into CCO:B0069581 ! PSRC1_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0069582 ! PSRC1_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0069583 ! PSRC1_HUMAN-Phosphothreonine145 relationship: transforms_into CCO:B0069584 ! PSRC1_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0069585 ! PSRC1_HUMAN-Phosphoserine190 [Term] id: CCO:B0043830 name: H1FNT_HUMAN def: "Testis-specific H1 histone" [UniProtKB:Q75WM6] synonym: "Haploid germ cell-specific nuclear protein 1" EXACT [UniProtKB:Q75WM6] synonym: "Histone H1t2" EXACT [UniProtKB:Q75WM6] xref: EMBL:AAI18636.1 xref: EMBL:AAI19788.1 xref: EMBL:AAP60022.1 xref: EMBL:AAS49492.1 xref: EMBL:BAD13382.2 xref: UniProtKB:Q147U8 xref: UniProtKB:Q5GKZ5 xref: UniProtKB:Q75WM6 xref: UniProtKB:Q7Z694 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018096 ! H1FNT_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000117 ! nuclear chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000090 ! mitotic chromosome condensation [Term] id: CCO:B0043831 name: H1FOO_HUMAN def: "Histone H1oo" [UniProtKB:Q8IZA3] synonym: "Oocyte-specific histone H1" EXACT [UniProtKB:Q8IZA3] synonym: "Oocyte-specific linker histone H1" EXACT [UniProtKB:Q8IZA3] synonym: "osH1" EXACT [UniProtKB:Q8IZA3] xref: EMBL:AAH47943.1 xref: EMBL:AAN46899.1 xref: EMBL:EAW79242.1 xref: EMBL:EAW79243.1 xref: UniProtKB:Q86WT7 xref: UniProtKB:Q8IZA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018097 ! H1FOO_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000117 ! meiosis [Term] id: CCO:B0043832 name: MLL5_HUMAN def: "Histone-lysine N-methyltransferase MLL5" [UniProtKB:Q8IZD2] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q8IZD2] synonym: "Lysine N-methyltransferase 2E" EXACT [UniProtKB:Q8IZD2] synonym: "Myeloid/lymphoid or mixed-lineage leukemia protein 5" EXACT [UniProtKB:Q8IZD2] xref: EMBL:AAH01296.1 xref: EMBL:AAH40004.1 xref: EMBL:AAH53906.1 xref: EMBL:AAH62583.1 xref: EMBL:AAI42988.1 xref: EMBL:AAM74947.1 xref: EMBL:AAN17675.1 xref: EMBL:AAN76325.1 xref: EMBL:AAO47009.1 xref: EMBL:AAO47010.1 xref: EMBL:AAO64395.1 xref: EMBL:AAO89072.1 xref: EMBL:AAR13893.1 xref: EMBL:BAA91435.1 xref: EMBL:EAW83356.1 xref: UniProtKB:Q6P5Y2 xref: UniProtKB:Q6PKG4 xref: UniProtKB:Q6T316 xref: UniProtKB:Q86TI3 xref: UniProtKB:Q86W12 xref: UniProtKB:Q86WG0 xref: UniProtKB:Q86WL2 xref: UniProtKB:Q8IV78 xref: UniProtKB:Q8IWR5 xref: UniProtKB:Q8IZD2 xref: UniProtKB:Q8NFF8 xref: UniProtKB:Q9NWE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008491 ! MLL5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000067 ! cell cycle arrest relationship: transforms_into CCO:B0048327 ! MLL5_HUMAN-Phosphoserine1405 [Term] id: CCO:B0043833 name: SC5A8_HUMAN def: "Sodium-coupled monocarboxylate transporter 1" [UniProtKB:Q8N695] synonym: "Apical iodide transporter" EXACT [UniProtKB:Q8N695] synonym: "Electrogenic sodium monocarboxylate cotransporter" EXACT [UniProtKB:Q8N695] synonym: "Sodium iodide-related cotransporter" EXACT [UniProtKB:Q8N695] synonym: "Solute carrier family 5 member 8" EXACT [UniProtKB:Q8N695] xref: EMBL:AAI10493.1 xref: EMBL:AAL88746.1 xref: EMBL:AAP46193.1 xref: EMBL:AAP46194.1 xref: EMBL:EAW97649.1 xref: UniProtKB:Q2TB99 xref: UniProtKB:Q7Z2H9 xref: UniProtKB:Q8N695 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014364 ! SLC5A8_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0002742 ! symporter activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0043834 name: URG4_HUMAN def: "Protein URG4" [UniProtKB:Q8TCY9] synonym: "HBV X protein up-regulated gene 4 protein" EXACT [UniProtKB:Q8TCY9] synonym: "HBxAg up-regulated gene 4 protein" EXACT [UniProtKB:Q8TCY9] xref: EMBL:AAH18426.2 xref: EMBL:AAL83710.1 xref: EMBL:BAA91312.1 xref: EMBL:BAA96031.1 xref: EMBL:CAE45880.1 xref: EMBL:CAH18244.1 xref: EMBL:CAH56246.1 xref: UniProtKB:Q658M4 xref: UniProtKB:Q68DH6 xref: UniProtKB:Q6MZZ5 xref: UniProtKB:Q8TCY9 xref: UniProtKB:Q8WV98 xref: UniProtKB:Q9NWR7 xref: UniProtKB:Q9P221 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014369 ! URG4_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000066 ! cell cycle [Term] id: CCO:B0043835 name: CTF18_HUMAN def: "Chromosome transmission fidelity protein 18 homolog" [UniProtKB:Q8WVB6] synonym: "hCTF18" EXACT [UniProtKB:Q8WVB6] xref: EMBL:AAH06278.2 xref: EMBL:AAH06437.1 xref: EMBL:AAH18184.1 xref: EMBL:BAB15766.1 xref: EMBL:CAB53056.1 xref: EMBL:EAW85706.1 xref: UniProtKB:Q7Z6Y6 xref: UniProtKB:Q8WVB6 xref: UniProtKB:Q9BR83 xref: UniProtKB:Q9BRG5 xref: UniProtKB:Q9H7K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008897 ! CHTF18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0048208 ! CTF18_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0048209 ! CTF18_HUMAN-Phosphoserine871 relationship: transforms_into CCO:B0064572 ! CTF18_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0064573 ! CTF18_HUMAN-Phosphoserine865 [Term] id: CCO:B0043836 name: BBS4_HUMAN def: "Bardet-Biedl syndrome 4 protein" [UniProtKB:Q96RK4] xref: EMBL:AAH08923.2 xref: EMBL:AAH27624.1 xref: EMBL:AAK58868.1 xref: EMBL:AAS13441.1 xref: EMBL:BAC11547.1 xref: UniProtKB:Q53DZ5 xref: UniProtKB:Q8NHU9 xref: UniProtKB:Q96H45 xref: UniProtKB:Q96RK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014342 ! BBS4_human relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005781 ! alpha-tubulin binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_function CCO:F0008391 ! dynactin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000043 ! pericentriolar material relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000384 ! centriole relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000484 ! basal body relationship: located_in CCO:C0001281 ! nonmotile primary cilium relationship: located_in CCO:C0001282 ! motile secondary cilium relationship: located_in CCO:C0002044 ! cilium membrane relationship: located_in CCO:C0002178 ! centriolar satellite relationship: located_in CCO:C0002182 ! BBSome relationship: participates_in CCO:P0000212 ! cytokinesis during cell cycle relationship: participates_in CCO:P0001625 ! regulation of cytokinesis [Term] id: CCO:B0043837 name: ST20_HUMAN def: "Suppressor of tumorigenicity protein 20" [UniProtKB:Q9HBF5] synonym: "Cervical cancer suppressor 1" EXACT [UniProtKB:Q9HBF5] synonym: "HCCS-1" EXACT [UniProtKB:Q9HBF5] xref: EMBL:AAG17280.1 xref: UniProtKB:Q9HBF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014368 ! ST20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000066 ! cell cycle relationship: participates_in CCO:P0000246 ! negative regulation of cell cycle [Term] id: CCO:B0043838 name: FMN2_HUMAN def: "Formin-2" [UniProtKB:Q9NZ56] xref: EMBL:AAF72884.1 xref: EMBL:AAF72885.1 xref: EMBL:BAD92390.1 xref: EMBL:CAQ08405.1 xref: EMBL:CAQ10135.1 xref: EMBL:CAQ10526.1 xref: EMBL:CAQ10976.1 xref: UniProtKB:B0QZA7 xref: UniProtKB:Q59GF6 xref: UniProtKB:Q5VU37 xref: UniProtKB:Q9NZ55 xref: UniProtKB:Q9NZ56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014348 ! FMN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000123 ! meiotic metaphase I relationship: participates_in CCO:P0000155 ! meiotic chromosome movement towards spindle pole relationship: participates_in CCO:P0000227 ! polar body extrusion after meiotic divisions relationship: participates_in CCO:P0000298 ! establishment of meiotic spindle localization relationship: transforms_into CCO:B0048262 ! FMN2_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0048263 ! FMN2_HUMAN-Phosphoserine396 relationship: transforms_into CCO:B0048264 ! FMN2_HUMAN-Phosphoserine400 relationship: transforms_into CCO:B0048265 ! FMN2_HUMAN-Phosphoserine404 relationship: transforms_into CCO:B0048266 ! FMN2_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0048267 ! FMN2_HUMAN-Phosphothreonine746 [Term] id: CCO:B0043861 name: K1549_HUMAN def: "UPF0606 protein KIAA1549" [UniProtKB:Q9HCM3] xref: EMBL:AAH38232.1 xref: EMBL:AAH91523.1 xref: EMBL:BAB13375.2 xref: EMBL:CAB66670.2 xref: UniProtKB:Q5BJD6 xref: UniProtKB:Q8IY15 xref: UniProtKB:Q9H0M3 xref: UniProtKB:Q9HCM3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006049 ! KIAA1549_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006476 ! kiaa1549-bpag1 physical interaction relationship: participates_in CCO:I0017302 ! kiaa1549-itsn2 physical interaction relationship: transforms_into CCO:B0048304 ! K1549_HUMAN-Phosphoserine1319 relationship: transforms_into CCO:B0048305 ! K1549_HUMAN-Phosphoserine1508 [Term] id: CCO:B0043862 name: CC85B_HUMAN def: "Coiled-coil domain-containing protein 85B" [UniProtKB:Q15834] synonym: "Delta-interacting protein A" EXACT [UniProtKB:Q15834] synonym: "Hepatitis delta antigen-interacting protein A" EXACT [UniProtKB:Q15834] xref: EMBL:AAB05928.1 xref: EMBL:AAH08796.1 xref: UniProtKB:Q15834 xref: UniProtKB:Q96HA0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004471 ! CCDC85B_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006659 ! gfi1b-ccdc85b physical interaction [Term] id: CCO:B0043863 name: KBP_HUMAN def: "KIF1-binding protein" [UniProtKB:Q96EK5] xref: EMBL:AAH12180.1 xref: EMBL:BAA86593.1 xref: EMBL:BAF84032.1 xref: EMBL:CAB43311.1 xref: EMBL:CAH72378.1 xref: UniProtKB:A8K5M8 xref: UniProtKB:Q96EK5 xref: UniProtKB:Q9BR89 xref: UniProtKB:Q9ULE1 xref: UniProtKB:Q9Y428 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004917 ! KIAA1279_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004206 ! kinesin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0006662 ! hbp1-kiaa1279 physical interaction relationship: participates_in CCO:I0015173 ! kiaa1279-znf670 physical interaction relationship: participates_in CCO:I0015208 ! kiaa1279-rgr physical interaction relationship: participates_in CCO:I0019114 ! atxn2-kiaa1279 physical interaction relationship: participates_in CCO:I0019120 ! atxn2-kiaa1279-1 physical interaction relationship: participates_in CCO:I0019410 ! rgr-kiaa1279 physical interaction [Term] id: CCO:B0043864 name: EED_HUMAN def: "Polycomb protein EED" [UniProtKB:O75530] synonym: "hEED" EXACT [UniProtKB:O75530] synonym: "WAIT-1" EXACT [UniProtKB:O75530] synonym: "WD protein associating with integrin cytoplasmic tails 1" EXACT [UniProtKB:O75530] xref: EMBL:AAC23685.1 xref: EMBL:AAC68675.1 xref: EMBL:AAC95144.1 xref: EMBL:AAD08714.1 xref: EMBL:AAD08815.1 xref: EMBL:AAH47672.1 xref: EMBL:AAH68995.1 xref: EMBL:BAF84809.1 xref: EMBL:EAW75129.1 xref: EMBL:EAW75130.1 xref: UniProtKB:A8K7V5 xref: UniProtKB:O00149 xref: UniProtKB:O75530 xref: UniProtKB:Q6NTH2 xref: UniProtKB:Q7LDA5 xref: UniProtKB:Q7LDG8 xref: UniProtKB:Q86VV2 xref: UniProtKB:Q9UNY7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005983 ! EED_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005616 ! histone methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001617 ! ESC/E(Z) complex relationship: participates_in CCO:I0006813 ! cul4a-eed physical interaction relationship: participates_in CCO:I0008526 ! eed-ddb1 physical interaction relationship: participates_in CCO:I0018729 ! eed-hdac1 physical interaction [Term] id: CCO:B0043865 name: MLL4_HUMAN def: "Histone-lysine N-methyltransferase MLL4" [UniProtKB:Q9UMN6] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9UMN6] synonym: "Lysine N-methyltransferase 2D" EXACT [UniProtKB:Q9UMN6] synonym: "Myeloid/lymphoid or mixed-lineage leukemia protein 4" EXACT [UniProtKB:Q9UMN6] synonym: "Trithorax homolog 2" EXACT [UniProtKB:Q9UMN6] synonym: "WBP-7" EXACT [UniProtKB:Q9UMN6] synonym: "WW domain-binding protein 7" EXACT [UniProtKB:Q9UMN6] xref: EMBL:AAD17932.1 xref: EMBL:AAD26112.1 xref: EMBL:AAD26113.1 xref: EMBL:AAD56420.1 xref: EMBL:AAH07353.2 xref: EMBL:AAH09337.2 xref: EMBL:BAA20763.3 xref: EMBL:CAB45385.1 xref: UniProtKB:O15022 xref: UniProtKB:O95836 xref: UniProtKB:Q96GP2 xref: UniProtKB:Q96IP3 xref: UniProtKB:Q9UK25 xref: UniProtKB:Q9UMN6 xref: UniProtKB:Q9Y668 xref: UniProtKB:Q9Y669 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005915 ! WBP7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0019049 ! atxn1-mll4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002770 ! chromatin-mediated maintenance of transcription relationship: transforms_into CCO:B0048323 ! MLL4_HUMAN-Phosphothreonine159 relationship: transforms_into CCO:B0048324 ! MLL4_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0048325 ! MLL4_HUMAN-Phosphoserine861 relationship: transforms_into CCO:B0048326 ! MLL4_HUMAN-Phosphoserine1164 relationship: transforms_into CCO:B0068227 ! MLL4_HUMAN-Phosphothreonine172 relationship: transforms_into CCO:B0068228 ! MLL4_HUMAN-Phosphothreonine176 relationship: transforms_into CCO:B0068229 ! MLL4_HUMAN-Phosphoserine821 relationship: transforms_into CCO:B0068230 ! MLL4_HUMAN-Phosphoserine844 relationship: transforms_into CCO:B0068231 ! MLL4_HUMAN-Phosphoserine1032 relationship: transforms_into CCO:B0068232 ! MLL4_HUMAN-Phosphoserine1035 relationship: transforms_into CCO:B0068233 ! MLL4_HUMAN-Phosphoserine1930 relationship: transforms_into CCO:B0068234 ! MLL4_HUMAN-Phosphothreonine1935 [Term] id: CCO:B0043866 name: LPAR2_HUMAN def: "Lysophosphatidic acid receptor 2" [UniProtKB:Q9HBW0] synonym: "LPA receptor 2" EXACT [UniProtKB:Q9HBW0] synonym: "LPA-2" EXACT [UniProtKB:Q9HBW0] synonym: "Lysophosphatidic acid receptor Edg-4" EXACT [UniProtKB:Q9HBW0] xref: EMBL:AAB61528.1 xref: EMBL:AAC27728.1 xref: EMBL:AAF43409.1 xref: EMBL:AAG28521.1 xref: EMBL:AAH25695.1 xref: EMBL:AAP84361.1 xref: UniProtKB:O00543 xref: UniProtKB:O43431 xref: UniProtKB:Q9HBW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014358 ! LPAR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0004370 ! LIM domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:I0017486 ! cftr-edg4 physical interaction relationship: participates_in CCO:I0017797 ! cftr-slc9a3r2-2 physical interaction relationship: participates_in CCO:I0017798 ! cftr-slc9a3r2-3 physical interaction relationship: participates_in CCO:I0017822 ! cftr-nhe2-1 physical interaction relationship: participates_in CCO:I0018717 ! cftr-nhe2 physical interaction relationship: participates_in CCO:I0019329 ! cftr-slc9a3r2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity [Term] id: CCO:B0043867 name: LPAR4_HUMAN def: "Lysophosphatidic acid receptor 4" [UniProtKB:Q99677] synonym: "G-protein coupled receptor 23" EXACT [UniProtKB:Q99677] synonym: "LPA receptor 4" EXACT [UniProtKB:Q99677] synonym: "LPA-4" EXACT [UniProtKB:Q99677] synonym: "P2Y purinoceptor 9" EXACT [UniProtKB:Q99677] synonym: "P2Y5-like receptor" EXACT [UniProtKB:Q99677] synonym: "P2Y9" EXACT [UniProtKB:Q99677] synonym: "Purinergic receptor 9" EXACT [UniProtKB:Q99677] xref: EMBL:AAB62087.1 xref: EMBL:AAB62088.1 xref: EMBL:AAB66322.1 xref: EMBL:AAC51301.1 xref: EMBL:AAH69996.1 xref: EMBL:AAH74722.1 xref: EMBL:AAH95538.1 xref: EMBL:AAP58404.1 xref: EMBL:CAD18851.1 xref: UniProtKB:O15132 xref: UniProtKB:Q502U9 xref: UniProtKB:Q6NSP5 xref: UniProtKB:Q99677 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014359 ! LPAR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007769 ! bcl6-hdac5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0043869 name: U119A_HUMAN def: "Protein unc-119 homolog A" [UniProtKB:Q13432] synonym: "hRG4" EXACT [UniProtKB:Q13432] synonym: "Retinal protein 4" EXACT [UniProtKB:Q13432] xref: EMBL:AAC50360.1 xref: EMBL:AAD01875.1 xref: EMBL:AAD01876.1 xref: EMBL:AAD31422.1 xref: EMBL:AAH27176.1 xref: UniProtKB:O95126 xref: UniProtKB:Q13432 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005883 ! UNC119_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0007983 ! cdkn2c-unc119 physical interaction relationship: participates_in CCO:I0008007 ! cks2-unc119 physical interaction relationship: participates_in CCO:I0008039 ! psmd2-unc119 physical interaction relationship: participates_in CCO:I0008087 ! cetn3-unc119 physical interaction relationship: participates_in CCO:I0008135 ! mphosph6-unc119 physical interaction relationship: participates_in CCO:I0008182 ! tp53bp2-unc119 physical interaction relationship: participates_in CCO:I0008184 ! ube2i-unc119 physical interaction relationship: participates_in CCO:I0019532 ! cdc42-unc119 physical interaction relationship: participates_in CCO:I0019553 ! tp53i3-unc119 physical interaction relationship: participates_in CCO:I0019562 ! arf4l-unc119 physical interaction relationship: participates_in CCO:I0019575 ! ccl18-unc119 physical interaction relationship: participates_in CCO:I0019584 ! dnmt2-unc119 physical interaction relationship: participates_in CCO:I0019595 ! hspe1-unc119 physical interaction relationship: participates_in CCO:I0019599 ! lama4-unc119 physical interaction relationship: participates_in CCO:I0019611 ! rfc5-unc119 physical interaction relationship: participates_in CCO:I0019613 ! rpa2-unc119 physical interaction relationship: participates_in CCO:I0019621 ! serpinb9-unc119 physical interaction relationship: participates_in CCO:I0019634 ! tk1-unc119 physical interaction relationship: participates_in CCO:I0019635 ! tmsb4x-unc119 physical interaction relationship: participates_in CCO:I0019642 ! znf24-unc119 physical interaction relationship: participates_in CCO:I0019647 ! anxa3-unc119 physical interaction relationship: participates_in CCO:I0019656 ! arl3-unc119 physical interaction relationship: participates_in CCO:I0019667 ! bcr-unc119 physical interaction relationship: participates_in CCO:I0019685 ! cbx8-unc119 physical interaction relationship: participates_in CCO:I0019733 ! hmgb1-unc119 physical interaction relationship: participates_in CCO:I0019743 ! id2-unc119 physical interaction relationship: participates_in CCO:I0019753 ! itsn1-unc119 physical interaction relationship: participates_in CCO:I0019764 ! mapk10-unc119 physical interaction relationship: participates_in CCO:I0019786 ! pfn1-unc119 physical interaction relationship: participates_in CCO:I0019880 ! zfp64-unc119 physical interaction relationship: participates_in CCO:I0019913 ! ash2l-unc119 physical interaction relationship: participates_in CCO:I0020109 ! phf10-unc119 physical interaction relationship: participates_in CCO:I0020160 ! s100a4-unc119 physical interaction relationship: participates_in CCO:I0020227 ! aof2-unc119 physical interaction relationship: participates_in CCO:I0020437 ! ripx-unc119 physical interaction relationship: transforms_into CCO:B0048419 ! U119A_HUMAN-Phosphoserine37 [Term] id: CCO:B0043870 name: SNAPN_HUMAN def: "SNARE-associated protein Snapin" [UniProtKB:O95295] synonym: "SNAP-associated protein" EXACT [UniProtKB:O95295] synonym: "Synaptosomal-associated protein 25-binding protein" EXACT [UniProtKB:O95295] xref: EMBL:AAD11417.1 xref: EMBL:AAH00761.1 xref: EMBL:AAH04494.1 xref: EMBL:AAP35399.1 xref: EMBL:BAB14927.1 xref: UniProtKB:O95295 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014367 ! SNAPIN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008321 ! snapap-spag5 physical interaction relationship: participates_in CCO:I0018577 ! st7-snap25bp-1 physical interaction relationship: participates_in CCO:I0019580 ! ddr1-snapap physical interaction relationship: participates_in CCO:I0019627 ! snapap-ikbkap physical interaction relationship: participates_in CCO:I0019838 ! snapap-htatip physical interaction relationship: participates_in CCO:I0019839 ! snapap-myst2 physical interaction relationship: participates_in CCO:I0020456 ! snapap-lamc1 physical interaction relationship: transforms_into CCO:B0048397 ! SNAPN_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 [Term] id: CCO:B0048149 name: 1433G_HUMAN-Phosphothreonine145 def: "Protein 1433G_HUMAN with the residue 145 substituted with Phosphothreonine" [UniProtKB:P61981] xref: UniProtKB:P61981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001893 ! protein kinase C inhibitor activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005489 ! 1433G_HUMAN [Term] id: CCO:B0048150 name: 4ET_HUMAN-Phosphoserine74 def: "Protein 4ET_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0048151 name: AAPK1_HUMAN-Phosphothreonine373 def: "Protein AAPK1_HUMAN with the residue 373 substituted with Phosphothreonine" [UniProtKB:Q13131] xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0048152 name: ABI1_HUMAN-Phosphotyrosine213 def: "Protein ABI1_HUMAN with the residue 213 substituted with Phosphotyrosine" [UniProtKB:Q8IZP0] xref: UniProtKB:Q8IZP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:B0048153 name: ACACA_HUMAN-N-acetylmethionine1 def: "Protein ACACA_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0048154 name: ACACA_HUMAN-Phosphoserine488 def: "Protein ACACA_HUMAN with the residue 488 substituted with Phosphoserine" [UniProtKB:Q13085] xref: UniProtKB:Q13085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:B0048155 name: ACD_HUMAN-Phosphothreonine422 def: "Protein ACD_HUMAN with the residue 422 substituted with Phosphothreonine" [UniProtKB:Q96AP0] xref: UniProtKB:Q96AP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005504 ! ACD_HUMAN [Term] id: CCO:B0048156 name: ACD_HUMAN-Phosphoserine425 def: "Protein ACD_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:Q96AP0] xref: UniProtKB:Q96AP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005504 ! ACD_HUMAN [Term] id: CCO:B0048157 name: ANKZ1_HUMAN-Phosphoserine675 def: "Protein ANKZ1_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:Q9H8Y5] xref: UniProtKB:Q9H8Y5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006329 ! ANKZ1_HUMAN [Term] id: CCO:B0048158 name: ANLN_HUMAN-Phosphoserine97 def: "Protein ANLN_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0048159 name: ANLN_HUMAN-Phosphoserine102 def: "Protein ANLN_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0048160 name: ANLN_HUMAN-Phosphoserine661 def: "Protein ANLN_HUMAN with the residue 661 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0048161 name: ANXA2_HUMAN-Phosphotyrosine188 def: "Protein ANXA2_HUMAN with the residue 188 substituted with Phosphotyrosine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0048162 name: APC1_HUMAN-Phosphoserine362 def: "Protein APC1_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0048163 name: APC1_HUMAN-Phosphoserine569 def: "Protein APC1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0048164 name: APC_HUMAN-Phosphoserine2125 def: "Protein APC_HUMAN with the residue 2125 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0048165 name: APC_HUMAN-Phosphoserine2671 def: "Protein APC_HUMAN with the residue 2671 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0048166 name: APC_HUMAN-Phosphothreonine2676 def: "Protein APC_HUMAN with the residue 2676 substituted with Phosphothreonine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0048167 name: APC_HUMAN-Phosphoserine2789 def: "Protein APC_HUMAN with the residue 2789 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0048168 name: APC_HUMAN-Phosphoserine2835 def: "Protein APC_HUMAN with the residue 2835 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0048169 name: APC_HUMAN-Phosphoserine2837 def: "Protein APC_HUMAN with the residue 2837 substituted with Phosphoserine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0048170 name: APC_HUMAN-Phosphotyrosine2838 def: "Protein APC_HUMAN with the residue 2838 substituted with Phosphotyrosine" [UniProtKB:P25054] xref: UniProtKB:P25054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001556 ! APC_HUMAN [Term] id: CCO:B0048171 name: ARAF_HUMAN-Phosphothreonine213 def: "Protein ARAF_HUMAN with the residue 213 substituted with Phosphothreonine" [UniProtKB:P10398] xref: UniProtKB:P10398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:B0048172 name: ARAF_HUMAN-Phosphothreonine215 def: "Protein ARAF_HUMAN with the residue 215 substituted with Phosphothreonine" [UniProtKB:P10398] xref: UniProtKB:P10398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:B0048173 name: ATF7_HUMAN-Phosphoserine108 def: "Protein ATF7_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:P17544] xref: UniProtKB:P17544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006016 ! ATF7_HUMAN [Term] id: CCO:B0048176 name: BAT2_HUMAN-Phosphothreonine609 def: "Protein BAT2_HUMAN with the residue 609 substituted with Phosphothreonine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0048177 name: BCR_HUMAN-Phosphoserine122 def: "Protein BCR_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:P11274] xref: UniProtKB:P11274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:B0048178 name: BMX_HUMAN-Phosphotyrosine216 def: "Protein BMX_HUMAN with the residue 216 substituted with Phosphotyrosine" [UniProtKB:P51813] comment: by autocatalysis; xref: UniProtKB:P51813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005923 ! BMX_HUMAN [Term] id: CCO:B0048179 name: BMX_HUMAN-Phosphotyrosine224 def: "Protein BMX_HUMAN with the residue 224 substituted with Phosphotyrosine" [UniProtKB:P51813] comment: by autocatalysis; xref: UniProtKB:P51813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005923 ! BMX_HUMAN [Term] id: CCO:B0048180 name: BRCA1_HUMAN-Phosphoserine1542 def: "Protein BRCA1_HUMAN with the residue 1542 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0048181 name: CABL1_HUMAN-Phosphothreonine415 def: "Protein CABL1_HUMAN with the residue 415 substituted with Phosphothreonine" [UniProtKB:Q8TDN4] xref: UniProtKB:Q8TDN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001994 ! CABL1_HUMAN [Term] id: CCO:B0048182 name: CCND1_HUMAN-Phosphotyrosine226 def: "Protein CCND1_HUMAN with the residue 226 substituted with Phosphotyrosine" [UniProtKB:P24385] xref: UniProtKB:P24385 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003204 ! cyclin-dependent protein kinase regulator activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:B0048183 name: CD2L5_HUMAN-Phosphoserine1054 def: "Protein CD2L5_HUMAN with the residue 1054 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0048184 name: CDC2_HUMAN-Phosphotyrosine160 def: "Protein CDC2_HUMAN with the residue 160 substituted with Phosphotyrosine" [UniProtKB:P06493] xref: UniProtKB:P06493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:B0048185 name: CDC5L_HUMAN-Phosphothreonine430 def: "Protein CDC5L_HUMAN with the residue 430 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0048186 name: CDC5L_HUMAN-Phosphoserine437 def: "Protein CDC5L_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0048187 name: CDC5L_HUMAN-Phosphothreonine438 def: "Protein CDC5L_HUMAN with the residue 438 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0048188 name: CDC5L_HUMAN-Phosphothreonine442 def: "Protein CDC5L_HUMAN with the residue 442 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0048189 name: CDCA3_HUMAN-Phosphothreonine70 def: "Protein CDCA3_HUMAN with the residue 70 substituted with Phosphothreonine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0048190 name: CDCA3_HUMAN-Phosphothreonine202 def: "Protein CDCA3_HUMAN with the residue 202 substituted with Phosphothreonine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0048191 name: CDCA5_HUMAN-Phosphothreonine159 def: "Protein CDCA5_HUMAN with the residue 159 substituted with Phosphothreonine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0048192 name: CDK3_HUMAN-Phosphotyrosine159 def: "Protein CDK3_HUMAN with the residue 159 substituted with Phosphotyrosine" [UniProtKB:Q00526] xref: UniProtKB:Q00526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001707 ! CDK3_HUMAN [Term] id: CCO:B0048193 name: CEND2_HUMAN-Phosphoserine188 def: "Protein CEND2_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:Q96P48] xref: UniProtKB:Q96P48 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002052 ! CEND2_HUMAN [Term] id: CCO:B0048194 name: CFTR_HUMAN-Phosphotyrosine515 def: "Protein CFTR_HUMAN with the residue 515 substituted with Phosphotyrosine" [UniProtKB:P13569] xref: UniProtKB:P13569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005605 ! CFTR_HUMAN [Term] id: CCO:B0048195 name: CHD8_HUMAN-Phosphoserine1903 def: "Protein CHD8_HUMAN with the residue 1903 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0048196 name: CHD8_HUMAN-Phosphoserine1921 def: "Protein CHD8_HUMAN with the residue 1921 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0048197 name: CHD8_HUMAN-Phosphoserine1923 def: "Protein CHD8_HUMAN with the residue 1923 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0048198 name: CHD8_HUMAN-Phosphoserine1932 def: "Protein CHD8_HUMAN with the residue 1932 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0048199 name: CHD8_HUMAN-Phosphoserine2239 def: "Protein CHD8_HUMAN with the residue 2239 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0048200 name: CHD8_HUMAN-Phosphoserine2240 def: "Protein CHD8_HUMAN with the residue 2240 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0048201 name: CLAP1_HUMAN-Phosphoserine646 def: "Protein CLAP1_HUMAN with the residue 646 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0048202 name: CLAP1_HUMAN-Phosphoserine1091 def: "Protein CLAP1_HUMAN with the residue 1091 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0048203 name: CLAP1_HUMAN-Phosphothreonine1099 def: "Protein CLAP1_HUMAN with the residue 1099 substituted with Phosphothreonine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0048204 name: CND1_HUMAN-Phosphothreonine586 def: "Protein CND1_HUMAN with the residue 586 substituted with Phosphothreonine" [UniProtKB:Q15021] xref: UniProtKB:Q15021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001801 ! CND1_HUMAN [Term] id: CCO:B0048205 name: CNDD3_HUMAN-Phosphoserine1329 def: "Protein CNDD3_HUMAN with the residue 1329 substituted with Phosphoserine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0048206 name: CNDD3_HUMAN-Phosphothreonine1331 def: "Protein CNDD3_HUMAN with the residue 1331 substituted with Phosphothreonine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0048207 name: CSN1_HUMAN-Phosphotyrosine357 def: "Protein CSN1_HUMAN with the residue 357 substituted with Phosphotyrosine" [UniProtKB:Q13098] xref: UniProtKB:Q13098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001740 ! CSN1_HUMAN [Term] id: CCO:B0048208 name: CTF18_HUMAN-Phosphoserine74 def: "Protein CTF18_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q8WVB6] xref: UniProtKB:Q8WVB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0043835 ! CTF18_HUMAN [Term] id: CCO:B0048209 name: CTF18_HUMAN-Phosphoserine871 def: "Protein CTF18_HUMAN with the residue 871 substituted with Phosphoserine" [UniProtKB:Q8WVB6] xref: UniProtKB:Q8WVB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043835 ! CTF18_HUMAN [Term] id: CCO:B0048210 name: CTNA1_HUMAN-Phosphothreonine645 def: "Protein CTNA1_HUMAN with the residue 645 substituted with Phosphothreonine" [UniProtKB:P35221] xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0048211 name: CTND1_HUMAN-Phosphoserine230 def: "Protein CTND1_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0048212 name: CTND1_HUMAN-Phosphoserine232 def: "Protein CTND1_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0048213 name: CTND1_HUMAN-Phosphoserine244 def: "Protein CTND1_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0048214 name: CTND1_HUMAN-Phosphothreonine869 def: "Protein CTND1_HUMAN with the residue 869 substituted with Phosphothreonine" [UniProtKB:O60716] xref: UniProtKB:O60716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005839 ! CTND1_HUMAN [Term] id: CCO:B0048215 name: CUL3_HUMAN-Phosphoserine450 def: "Protein CUL3_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q13618] comment: By similarity xref: UniProtKB:Q13618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001761 ! CUL3_HUMAN [Term] id: CCO:B0048216 name: CYTSA_HUMAN-Phosphoserine881 def: "Protein CYTSA_HUMAN with the residue 881 substituted with Phosphoserine" [UniProtKB:Q69YQ0] xref: UniProtKB:Q69YQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001906 ! CYTSA_HUMAN [Term] id: CCO:B0048217 name: DAXX_HUMAN-Phosphoserine178 def: "Protein DAXX_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000119 ! heterochromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0048218 name: DAXX_HUMAN-Phosphoserine688 def: "Protein DAXX_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0048219 name: DAXX_HUMAN-Phosphoserine690 def: "Protein DAXX_HUMAN with the residue 690 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0048220 name: DAXX_HUMAN-Phosphoserine702 def: "Protein DAXX_HUMAN with the residue 702 substituted with Phosphoserine" [UniProtKB:Q9UER7] xref: UniProtKB:Q9UER7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:B0048221 name: DCP1A_HUMAN-Phosphoserine315 def: "Protein DCP1A_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0048222 name: DCP1A_HUMAN-Phosphoserine319 def: "Protein DCP1A_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0048223 name: DCP1A_HUMAN-Phosphoserine334 def: "Protein DCP1A_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0048224 name: DCP1A_HUMAN-Phosphothreonine531 def: "Protein DCP1A_HUMAN with the residue 531 substituted with Phosphothreonine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0048225 name: DLG1_HUMAN-Phosphoserine619 def: "Protein DLG1_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:Q12959] xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0048226 name: DLG1_HUMAN-Phosphotyrosine760 def: "Protein DLG1_HUMAN with the residue 760 substituted with Phosphotyrosine" [UniProtKB:Q12959] xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0048227 name: DLGP5_HUMAN-Phosphoserine67 def: "Protein DLGP5_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048228 name: DLGP5_HUMAN-Phosphothreonine219 def: "Protein DLGP5_HUMAN with the residue 219 substituted with Phosphothreonine" [UniProtKB:Q15398] comment: By similarity xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048229 name: DLGP5_HUMAN-Phosphothreonine224 def: "Protein DLGP5_HUMAN with the residue 224 substituted with Phosphothreonine" [UniProtKB:Q15398] comment: By similarity xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048230 name: DLGP5_HUMAN-Phosphothreonine329 def: "Protein DLGP5_HUMAN with the residue 329 substituted with Phosphothreonine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048231 name: DLGP5_HUMAN-Phosphothreonine401 def: "Protein DLGP5_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001322 ! spindle pole centrosome relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048232 name: DLGP5_HUMAN-Phosphothreonine402 def: "Protein DLGP5_HUMAN with the residue 402 substituted with Phosphothreonine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048233 name: DLGP5_HUMAN-Phosphoserine618 def: "Protein DLGP5_HUMAN with the residue 618 substituted with Phosphoserine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048234 name: DLGP5_HUMAN-Phosphothreonine639 def: "Protein DLGP5_HUMAN with the residue 639 substituted with Phosphothreonine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048235 name: DLGP5_HUMAN-Phosphoserine642 def: "Protein DLGP5_HUMAN with the residue 642 substituted with Phosphoserine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048236 name: DLGP5_HUMAN-Phosphoserine662 def: "Protein DLGP5_HUMAN with the residue 662 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048237 name: DLGP5_HUMAN-Phosphoserine689 def: "Protein DLGP5_HUMAN with the residue 689 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048238 name: DLGP5_HUMAN-Phosphothreonine759 def: "Protein DLGP5_HUMAN with the residue 759 substituted with Phosphothreonine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048239 name: DLGP5_HUMAN-Phosphoserine774 def: "Protein DLGP5_HUMAN with the residue 774 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048240 name: DLGP5_HUMAN-Phosphoserine777 def: "Protein DLGP5_HUMAN with the residue 777 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048241 name: DLGP5_HUMAN-Phosphoserine806 def: "Protein DLGP5_HUMAN with the residue 806 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048242 name: DLGP5_HUMAN-Phosphoserine812 def: "Protein DLGP5_HUMAN with the residue 812 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048243 name: DLGP5_HUMAN-Phosphoserine830 def: "Protein DLGP5_HUMAN with the residue 830 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048244 name: DLGP5_HUMAN-Phosphoserine839 def: "Protein DLGP5_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:Q15398] comment: by CDC2; xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0048245 name: DREB_HUMAN-Phosphothreonine335 def: "Protein DREB_HUMAN with the residue 335 substituted with Phosphothreonine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0048246 name: E2F8_HUMAN-Phosphoserine357 def: "Protein E2F8_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:A0AVK6] xref: UniProtKB:A0AVK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001317 ! E2F8_HUMAN [Term] id: CCO:B0048247 name: EDC3_HUMAN-Phosphoserine161 def: "Protein EDC3_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q96F86] xref: UniProtKB:Q96F86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005717 ! EDC3_HUMAN [Term] id: CCO:B0048248 name: EDC4_HUMAN-Phosphoserine723 def: "Protein EDC4_HUMAN with the residue 723 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0048249 name: EDC4_HUMAN-Phosphoserine725 def: "Protein EDC4_HUMAN with the residue 725 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0048250 name: EDC4_HUMAN-Phosphothreonine727 def: "Protein EDC4_HUMAN with the residue 727 substituted with Phosphothreonine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0048251 name: EDC4_HUMAN-Phosphoserine734 def: "Protein EDC4_HUMAN with the residue 734 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0048252 name: EFNB1_HUMAN-Phosphotyrosine317 def: "Protein EFNB1_HUMAN with the residue 317 substituted with Phosphotyrosine" [UniProtKB:P98172] comment: By similarity xref: UniProtKB:P98172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006259 ! ephrin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0005815 ! EFNB1_HUMAN [Term] id: CCO:B0048253 name: EIF3D_HUMAN-Phosphothreonine548 def: "Protein EIF3D_HUMAN with the residue 548 substituted with Phosphothreonine" [UniProtKB:O15371] comment: By similarity xref: UniProtKB:O15371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026270 ! EIF3D_HUMAN [Term] id: CCO:B0048254 name: ERBB3_HUMAN-Phosphotyrosine1328 def: "Protein ERBB3_HUMAN with the residue 1328 substituted with Phosphotyrosine" [UniProtKB:P21860] comment: By similarity xref: UniProtKB:P21860 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004383 ! protein tyrosine kinase activator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0001751 ! receptor complex relationship: transformation_of CCO:B0005852 ! ERBB3_HUMAN [Term] id: CCO:B0048255 name: ERH_HUMAN-N-acetylserine2 def: "Protein ERH_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P84090] xref: UniProtKB:P84090 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001703 ! ERH_HUMAN [Term] id: CCO:B0048256 name: ESCO2_HUMAN-Phosphoserine512 def: "Protein ESCO2_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q56NI9] xref: UniProtKB:Q56NI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001841 ! ESCO2_HUMAN [Term] id: CCO:B0048257 name: EZH2_HUMAN-Phosphoserine21 def: "Protein EZH2_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q15910] comment: by PKB/AKT1; xref: UniProtKB:Q15910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:B0048258 name: FACD2_HUMAN-Phosphotyrosine684 def: "Protein FACD2_HUMAN with the residue 684 substituted with Phosphotyrosine" [UniProtKB:Q9BXW9] xref: UniProtKB:Q9BXW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:B0048259 name: FANCI_HUMAN-Phosphotyrosine215 def: "Protein FANCI_HUMAN with the residue 215 substituted with Phosphotyrosine" [UniProtKB:Q9NVI1] xref: UniProtKB:Q9NVI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002170 ! FANCI_HUMAN [Term] id: CCO:B0048260 name: FANCJ_HUMAN-Phosphoserine112 def: "Protein FANCJ_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0048261 name: FANCJ_HUMAN-Phosphothreonine113 def: "Protein FANCJ_HUMAN with the residue 113 substituted with Phosphothreonine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0048262 name: FMN2_HUMAN-Phosphoserine361 def: "Protein FMN2_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9NZ56] comment: By similarity xref: UniProtKB:Q9NZ56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043838 ! FMN2_HUMAN [Term] id: CCO:B0048263 name: FMN2_HUMAN-Phosphoserine396 def: "Protein FMN2_HUMAN with the residue 396 substituted with Phosphoserine" [UniProtKB:Q9NZ56] xref: UniProtKB:Q9NZ56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043838 ! FMN2_HUMAN [Term] id: CCO:B0048264 name: FMN2_HUMAN-Phosphoserine400 def: "Protein FMN2_HUMAN with the residue 400 substituted with Phosphoserine" [UniProtKB:Q9NZ56] xref: UniProtKB:Q9NZ56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0043838 ! FMN2_HUMAN [Term] id: CCO:B0048265 name: FMN2_HUMAN-Phosphoserine404 def: "Protein FMN2_HUMAN with the residue 404 substituted with Phosphoserine" [UniProtKB:Q9NZ56] xref: UniProtKB:Q9NZ56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043838 ! FMN2_HUMAN [Term] id: CCO:B0048266 name: FMN2_HUMAN-Phosphoserine516 def: "Protein FMN2_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q9NZ56] comment: By similarity xref: UniProtKB:Q9NZ56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043838 ! FMN2_HUMAN [Term] id: CCO:B0048267 name: FMN2_HUMAN-Phosphothreonine746 def: "Protein FMN2_HUMAN with the residue 746 substituted with Phosphothreonine" [UniProtKB:Q9NZ56] comment: By similarity xref: UniProtKB:Q9NZ56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043838 ! FMN2_HUMAN [Term] id: CCO:B0048268 name: FXR1_HUMAN-N-acetylalanine2 def: "Protein FXR1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P51114] xref: UniProtKB:P51114 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006140 ! FXR1_HUMAN [Term] id: CCO:B0048269 name: G3P_HUMAN-ADP-ribosylcysteine152 def: "Protein G3P_HUMAN with the residue 152 substituted with ADP-ribosylcysteine" [UniProtKB:P04406] comment: by autocatalysis; in irreversibly inhibited form; By similarity xref: UniProtKB:P04406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:B0048270 name: G3P_HUMAN-S-nitrosocysteine152 def: "Protein G3P_HUMAN with the residue 152 substituted with S-nitrosocysteine" [UniProtKB:P04406] comment: in reversibly inhibited form; By similarity xref: UniProtKB:P04406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:B0048271 name: GRLF1_HUMAN-Phosphoserine970 def: "Protein GRLF1_HUMAN with the residue 970 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0048272 name: GRWD1_HUMAN-Phosphothreonine10 def: "Protein GRWD1_HUMAN with the residue 10 substituted with Phosphothreonine" [UniProtKB:Q9BQ67] xref: UniProtKB:Q9BQ67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005687 ! GRWD1_HUMAN [Term] id: CCO:B0048273 name: GTSE1_HUMAN-Phosphoserine152 def: "Protein GTSE1_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0048274 name: HCFC2_HUMAN-Phosphotyrosine159 def: "Protein HCFC2_HUMAN with the residue 159 substituted with Phosphotyrosine" [UniProtKB:Q9Y5Z7] xref: UniProtKB:Q9Y5Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0036469 ! HCFC2_HUMAN [Term] id: CCO:B0048275 name: HEXI2_HUMAN-Phosphothreonine46 def: "Protein HEXI2_HUMAN with the residue 46 substituted with Phosphothreonine" [UniProtKB:Q96MH2] xref: UniProtKB:Q96MH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002049 ! HEXI2_HUMAN [Term] id: CCO:B0048276 name: HNRH1_HUMAN-N-acetylmethionine1 def: "Protein HNRH1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P31943] comment: alternate; xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0048277 name: HNRPC_HUMAN-Phosphoserine306 def: "Protein HNRPC_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0048278 name: HNRPG_HUMAN-Phosphoserine277 def: "Protein HNRPG_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0048279 name: HNRPG_HUMAN-Phosphoserine280 def: "Protein HNRPG_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0048280 name: HRX_HUMAN-Phosphoserine518 def: "Protein HRX_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0048281 name: HRX_HUMAN-Phosphothreonine1845 def: "Protein HRX_HUMAN with the residue 1845 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0048282 name: HUWE1_HUMAN-Phosphoserine1084 def: "Protein HUWE1_HUMAN with the residue 1084 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0048283 name: HUWE1_HUMAN-Phosphoserine2526 def: "Protein HUWE1_HUMAN with the residue 2526 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0048284 name: ILF3_HUMAN-Phosphothreonine486 def: "Protein ILF3_HUMAN with the residue 486 substituted with Phosphothreonine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0048285 name: IMA2_HUMAN-N-acetylserine2 def: "Protein IMA2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P52292] xref: UniProtKB:P52292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001657 ! IMA2_HUMAN [Term] id: CCO:B0048286 name: INCE_HUMAN-Phosphoserine72 def: "Protein INCE_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0048287 name: INPP_HUMAN-Phosphoserine317 def: "Protein INPP_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:P49441] xref: UniProtKB:P49441 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006332 ! INPP_HUMAN [Term] id: CCO:B0048288 name: ITF2_HUMAN-Phosphoserine372 def: "Protein ITF2_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:P15884] xref: UniProtKB:P15884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005715 ! ITF2_HUMAN [Term] id: CCO:B0048289 name: JAK3_HUMAN-Phosphoserine1027 def: "Protein JAK3_HUMAN with the residue 1027 substituted with Phosphoserine" [UniProtKB:P52333] comment: By similarity xref: UniProtKB:P52333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005612 ! JAK3_HUMAN [Term] id: CCO:B0048290 name: JAK3_HUMAN-Phosphoserine1031 def: "Protein JAK3_HUMAN with the residue 1031 substituted with Phosphoserine" [UniProtKB:P52333] comment: By similarity xref: UniProtKB:P52333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005612 ! JAK3_HUMAN [Term] id: CCO:B0048291 name: JHD1A_HUMAN-Phosphothreonine550 def: "Protein JHD1A_HUMAN with the residue 550 substituted with Phosphothreonine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048292 name: JHD1A_HUMAN-Phosphoserine558 def: "Protein JHD1A_HUMAN with the residue 558 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048293 name: JHD1A_HUMAN-Phosphothreonine713 def: "Protein JHD1A_HUMAN with the residue 713 substituted with Phosphothreonine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008199 ! histone demethylase activity (H3-K36 specific) relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048294 name: JHD1A_HUMAN-Phosphoserine718 def: "Protein JHD1A_HUMAN with the residue 718 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048295 name: JHD1A_HUMAN-Phosphothreonine720 def: "Protein JHD1A_HUMAN with the residue 720 substituted with Phosphothreonine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048296 name: JHD1A_HUMAN-Phosphoserine731 def: "Protein JHD1A_HUMAN with the residue 731 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048297 name: JHD1A_HUMAN-Phosphoserine739 def: "Protein JHD1A_HUMAN with the residue 739 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048298 name: JHD1A_HUMAN-Phosphoserine740 def: "Protein JHD1A_HUMAN with the residue 740 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0048299 name: JMY_HUMAN-Phosphoserine83 def: "Protein JMY_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q8N9B5] comment: By similarity xref: UniProtKB:Q8N9B5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040022 ! JMY_HUMAN [Term] id: CCO:B0048300 name: K1267_HUMAN-Phosphoserine268 def: "Protein K1267_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:Q7Z3B3] xref: UniProtKB:Q7Z3B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005600 ! K1267_HUMAN [Term] id: CCO:B0048301 name: K1267_HUMAN-Phosphoserine991 def: "Protein K1267_HUMAN with the residue 991 substituted with Phosphoserine" [UniProtKB:Q7Z3B3] xref: UniProtKB:Q7Z3B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005600 ! K1267_HUMAN [Term] id: CCO:B0048302 name: K1267_HUMAN-Phosphothreonine1003 def: "Protein K1267_HUMAN with the residue 1003 substituted with Phosphothreonine" [UniProtKB:Q7Z3B3] xref: UniProtKB:Q7Z3B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005600 ! K1267_HUMAN [Term] id: CCO:B0048303 name: K1267_HUMAN-Phosphoserine1045 def: "Protein K1267_HUMAN with the residue 1045 substituted with Phosphoserine" [UniProtKB:Q7Z3B3] xref: UniProtKB:Q7Z3B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005600 ! K1267_HUMAN [Term] id: CCO:B0048304 name: K1549_HUMAN-Phosphoserine1319 def: "Protein K1549_HUMAN with the residue 1319 substituted with Phosphoserine" [UniProtKB:Q9HCM3] xref: UniProtKB:Q9HCM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0043861 ! K1549_HUMAN [Term] id: CCO:B0048305 name: K1549_HUMAN-Phosphoserine1508 def: "Protein K1549_HUMAN with the residue 1508 substituted with Phosphoserine" [UniProtKB:Q9HCM3] comment: By similarity xref: UniProtKB:Q9HCM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043861 ! K1549_HUMAN [Term] id: CCO:B0048306 name: KC1E_HUMAN-Phosphoserine343 def: "Protein KC1E_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:P49674] xref: UniProtKB:P49674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005272 ! KC1E_HUMAN [Term] id: CCO:B0048307 name: KC1E_HUMAN-Phosphoserine389 def: "Protein KC1E_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:P49674] xref: UniProtKB:P49674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005272 ! KC1E_HUMAN [Term] id: CCO:B0048308 name: KIF23_HUMAN-Phosphothreonine913 def: "Protein KIF23_HUMAN with the residue 913 substituted with Phosphothreonine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0048309 name: LAP2_HUMAN-Phosphotyrosine1293 def: "Protein LAP2_HUMAN with the residue 1293 substituted with Phosphotyrosine" [UniProtKB:Q96RT1] comment: By similarity xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0048310 name: LATS1_HUMAN-Phosphotyrosine277 def: "Protein LATS1_HUMAN with the residue 277 substituted with Phosphotyrosine" [UniProtKB:O95835] xref: UniProtKB:O95835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001454 ! LATS1_HUMAN [Term] id: CCO:B0048311 name: LIN9_HUMAN-Phosphoserine321 def: "Protein LIN9_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q5TKA1] xref: UniProtKB:Q5TKA1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001894 ! LIN9_HUMAN [Term] id: CCO:B0048312 name: M3K1_HUMAN-Phosphoserine292 def: "Protein M3K1_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0048313 name: M3K3_HUMAN-Phosphoserine166 def: "Protein M3K3_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q99759] xref: UniProtKB:Q99759 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:B0048314 name: MACF4_HUMAN-Phosphotyrosine1554 def: "Protein MACF4_HUMAN with the residue 1554 substituted with Phosphotyrosine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0048315 name: MATR3_HUMAN-Phosphoserine206 def: "Protein MATR3_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000254 ! nuclear inner membrane relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0048316 name: MCM2_HUMAN-Phosphothreonine25 def: "Protein MCM2_HUMAN with the residue 25 substituted with Phosphothreonine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0048317 name: MCM4_HUMAN-Phosphoserine54 def: "Protein MCM4_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0048318 name: MDC1_HUMAN-Phosphoserine1399 def: "Protein MDC1_HUMAN with the residue 1399 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0048319 name: MDC1_HUMAN-Phosphothreonine1403 def: "Protein MDC1_HUMAN with the residue 1403 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0048320 name: MINT_HUMAN-Phosphoserine1918 def: "Protein MINT_HUMAN with the residue 1918 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0048321 name: MINT_HUMAN-Phosphoserine2481 def: "Protein MINT_HUMAN with the residue 2481 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0048322 name: MINT_HUMAN-Phosphoserine2493 def: "Protein MINT_HUMAN with the residue 2493 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0048323 name: MLL4_HUMAN-Phosphothreonine159 def: "Protein MLL4_HUMAN with the residue 159 substituted with Phosphothreonine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0048324 name: MLL4_HUMAN-Phosphoserine320 def: "Protein MLL4_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q9UMN6] comment: By similarity xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0048325 name: MLL4_HUMAN-Phosphoserine861 def: "Protein MLL4_HUMAN with the residue 861 substituted with Phosphoserine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0048326 name: MLL4_HUMAN-Phosphoserine1164 def: "Protein MLL4_HUMAN with the residue 1164 substituted with Phosphoserine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0048327 name: MLL5_HUMAN-Phosphoserine1405 def: "Protein MLL5_HUMAN with the residue 1405 substituted with Phosphoserine" [UniProtKB:Q8IZD2] xref: UniProtKB:Q8IZD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0043832 ! MLL5_HUMAN [Term] id: CCO:B0048328 name: MLTK_HUMAN-Phosphoserine591 def: "Protein MLTK_HUMAN with the residue 591 substituted with Phosphoserine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0048329 name: MLTK_HUMAN-Phosphoserine593 def: "Protein MLTK_HUMAN with the residue 593 substituted with Phosphoserine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0048330 name: MLTK_HUMAN-Phosphoserine599 def: "Protein MLTK_HUMAN with the residue 599 substituted with Phosphoserine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0048331 name: MSH3_HUMAN-Phosphotyrosine1068 def: "Protein MSH3_HUMAN with the residue 1068 substituted with Phosphotyrosine" [UniProtKB:P20585] xref: UniProtKB:P20585 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000094 ! purine-specific mismatch base pair DNA N-glycosylase activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004138 ! centromeric DNA binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_function CCO:F0004953 ! guanine/thymine mispair binding relationship: has_function CCO:F0004955 ! dinucleotide insertion or deletion binding relationship: has_function CCO:F0004958 ! single guanine insertion binding relationship: has_function CCO:F0004962 ! dinucleotide repeat insertion binding relationship: has_function CCO:F0004975 ! oxidized purine DNA binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001439 ! MutSbeta complex relationship: transformation_of CCO:B0005720 ! MSH3_HUMAN [Term] id: CCO:B0048332 name: NCOR2_HUMAN-Phosphoserine54 def: "Protein NCOR2_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0048333 name: NDE1_HUMAN-Phosphoserine211 def: "Protein NDE1_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0048334 name: NDE1_HUMAN-Phosphothreonine215 def: "Protein NDE1_HUMAN with the residue 215 substituted with Phosphothreonine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0048335 name: NDE1_HUMAN-Phosphothreonine228 def: "Protein NDE1_HUMAN with the residue 228 substituted with Phosphothreonine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0048336 name: NF1_HUMAN-Phosphotyrosine2577 def: "Protein NF1_HUMAN with the residue 2577 substituted with Phosphotyrosine" [UniProtKB:P21359] comment: By similarity xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0048337 name: NIPA_HUMAN-Phosphoserine395 def: "Protein NIPA_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0048338 name: NONO_HUMAN-Phosphoserine147 def: "Protein NONO_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:Q15233] xref: UniProtKB:Q15233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005234 ! NONO_HUMAN [Term] id: CCO:B0048339 name: NPM_HUMAN-Phosphoserine88 def: "Protein NPM_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0048340 name: NPM_HUMAN-Phosphothreonine279 def: "Protein NPM_HUMAN with the residue 279 substituted with Phosphothreonine" [UniProtKB:P06748] xref: UniProtKB:P06748 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004610 ! Tat protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:B0048341 name: NUMA1_HUMAN-Phosphoserine1969 def: "Protein NUMA1_HUMAN with the residue 1969 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0048342 name: NUSAP_HUMAN-Phosphoserine240 def: "Protein NUSAP_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0048343 name: NUSAP_HUMAN-Phosphothreonine244 def: "Protein NUSAP_HUMAN with the residue 244 substituted with Phosphothreonine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0048344 name: NUSAP_HUMAN-Phosphoserine247 def: "Protein NUSAP_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0048345 name: P66A_HUMAN-Phosphothreonine49 def: "Protein P66A_HUMAN with the residue 49 substituted with Phosphothreonine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0048346 name: P66A_HUMAN-Phosphoserine113 def: "Protein P66A_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0048347 name: P66B_HUMAN-Phosphoserine334 def: "Protein P66B_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0048348 name: P66B_HUMAN-Phosphoserine338 def: "Protein P66B_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0048349 name: PARD3_HUMAN-Phosphoserine143 def: "Protein PARD3_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0048350 name: PARD3_HUMAN-Phosphoserine695 def: "Protein PARD3_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0048351 name: PARD3_HUMAN-Phosphoserine715 def: "Protein PARD3_HUMAN with the residue 715 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0048352 name: PARD3_HUMAN-Phosphoserine728 def: "Protein PARD3_HUMAN with the residue 728 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0048353 name: PARD3_HUMAN-Phosphotyrosine1080 def: "Protein PARD3_HUMAN with the residue 1080 substituted with Phosphotyrosine" [UniProtKB:Q8TEW0] comment: By similarity xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0048354 name: PB1_HUMAN-Phosphoserine10 def: "Protein PB1_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0048355 name: PBX2_HUMAN-Phosphoserine151 def: "Protein PBX2_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:P40425] xref: UniProtKB:P40425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:B0048356 name: PKN1_HUMAN-Phosphothreonine778 def: "Protein PKN1_HUMAN with the residue 778 substituted with Phosphothreonine" [UniProtKB:Q16512] xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0048357 name: PLCG1_HUMAN-Phosphoserine1263 def: "Protein PLCG1_HUMAN with the residue 1263 substituted with Phosphoserine" [UniProtKB:P19174] xref: UniProtKB:P19174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:B0048358 name: PR285_HUMAN-Phosphotyrosine1507 def: "Protein PR285_HUMAN with the residue 1507 substituted with Phosphotyrosine" [UniProtKB:Q9BYK8] xref: UniProtKB:Q9BYK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0000934 ! ribonuclease activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006035 ! PR285_HUMAN [Term] id: CCO:B0048359 name: PSRC1_HUMAN-Phosphoserine70 def: "Protein PSRC1_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0048360 name: PSRC1_HUMAN-Phosphoserine122 def: "Protein PSRC1_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0048361 name: PSRC1_HUMAN-Phosphoserine212 def: "Protein PSRC1_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0048362 name: PSRC1_HUMAN-Phosphothreonine245 def: "Protein PSRC1_HUMAN with the residue 245 substituted with Phosphothreonine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: located_in CCO:C0001017 ! midbody relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0048363 name: PTTG1_HUMAN-Phosphoserine102 def: "Protein PTTG1_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:O95997] comment: By similarity xref: UniProtKB:O95997 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001457 ! PTTG1_HUMAN [Term] id: CCO:B0048364 name: RAF1_HUMAN-Phosphoserine257 def: "Protein RAF1_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:P04049] xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0048365 name: RAF1_HUMAN-Phosphothreonine258 def: "Protein RAF1_HUMAN with the residue 258 substituted with Phosphothreonine" [UniProtKB:P04049] xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0048366 name: RAF1_HUMAN-Phosphothreonine269 def: "Protein RAF1_HUMAN with the residue 269 substituted with Phosphothreonine" [UniProtKB:P04049] comment: by PKA; xref: UniProtKB:P04049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:B0048367 name: RAI1_HUMAN-Phosphoserine345 def: "Protein RAI1_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0048368 name: RASF8_HUMAN-Phosphoserine83 def: "Protein RASF8_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q8NHQ8] comment: By similarity xref: UniProtKB:Q8NHQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043423 ! RASF8_HUMAN [Term] id: CCO:B0048369 name: RASF8_HUMAN-Phosphoserine85 def: "Protein RASF8_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q8NHQ8] comment: By similarity xref: UniProtKB:Q8NHQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043423 ! RASF8_HUMAN [Term] id: CCO:B0048370 name: RASH_HUMAN-S-nitrosocysteine118 def: "Protein RASH_HUMAN with the residue 118 substituted with S-nitrosocysteine" [UniProtKB:P01112] xref: UniProtKB:P01112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001467 ! RASH_HUMAN [Term] id: CCO:B0048371 name: RB15B_HUMAN-Phosphoserine235 def: "Protein RB15B_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q8NDT2] xref: UniProtKB:Q8NDT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:B0048372 name: RB_HUMAN-Phosphothreonine356 def: "Protein RB_HUMAN with the residue 356 substituted with Phosphothreonine" [UniProtKB:P06400] xref: UniProtKB:P06400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001491 ! RB_HUMAN [Term] id: CCO:B0048373 name: RENT1_HUMAN-Phosphotyrosine1129 def: "Protein RENT1_HUMAN with the residue 1129 substituted with Phosphotyrosine" [UniProtKB:Q92900] xref: UniProtKB:Q92900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002024 ! RENT1_HUMAN [Term] id: CCO:B0048374 name: RERE_HUMAN-Phosphoserine304 def: "Protein RERE_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0048375 name: RERE_HUMAN-Phosphoserine1106 def: "Protein RERE_HUMAN with the residue 1106 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0048376 name: RERE_HUMAN-Phosphoserine1113 def: "Protein RERE_HUMAN with the residue 1113 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0048377 name: RERE_HUMAN-Phosphoserine1115 def: "Protein RERE_HUMAN with the residue 1115 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0048378 name: RFC1_HUMAN-Phosphotyrosine670 def: "Protein RFC1_HUMAN with the residue 670 substituted with Phosphotyrosine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0048379 name: RFC1_HUMAN-Phosphotyrosine672 def: "Protein RFC1_HUMAN with the residue 672 substituted with Phosphotyrosine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0048380 name: RIN1_HUMAN-Phosphotyrosine632 def: "Protein RIN1_HUMAN with the residue 632 substituted with Phosphotyrosine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0048381 name: RNF31_HUMAN-Phosphoserine466 def: "Protein RNF31_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q96EP0] xref: UniProtKB:Q96EP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005982 ! RNF31_HUMAN [Term] id: CCO:B0048382 name: RS20_HUMAN-N-acetylalanine2 def: "Protein RS20_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P60866] xref: UniProtKB:P60866 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005563 ! RS20_HUMAN [Term] id: CCO:B0048383 name: RUNX3_HUMAN-Phosphoserine243 def: "Protein RUNX3_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:Q13761] xref: UniProtKB:Q13761 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001766 ! RUNX3_HUMAN [Term] id: CCO:B0048384 name: SBDS_HUMAN-N-acetylserine2 def: "Protein SBDS_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9Y3A5] xref: UniProtKB:Q9Y3A5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025212 ! SBDS_HUMAN [Term] id: CCO:B0048385 name: SBDS_HUMAN-Phosphothreonine124 def: "Protein SBDS_HUMAN with the residue 124 substituted with Phosphothreonine" [UniProtKB:Q9Y3A5] xref: UniProtKB:Q9Y3A5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025212 ! SBDS_HUMAN [Term] id: CCO:B0048386 name: SBDS_HUMAN-Phosphotyrosine128 def: "Protein SBDS_HUMAN with the residue 128 substituted with Phosphotyrosine" [UniProtKB:Q9Y3A5] xref: UniProtKB:Q9Y3A5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025212 ! SBDS_HUMAN [Term] id: CCO:B0048387 name: SC65_HUMAN-Phosphotyrosine234 def: "Protein SC65_HUMAN with the residue 234 substituted with Phosphotyrosine" [UniProtKB:Q92791] xref: UniProtKB:Q92791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002018 ! SC65_HUMAN [Term] id: CCO:B0048388 name: SCNM1_HUMAN-Phosphoserine183 def: "Protein SCNM1_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q9BWG6] xref: UniProtKB:Q9BWG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005251 ! SCNM1_HUMAN [Term] id: CCO:B0048389 name: SDS3_HUMAN-Phosphoserine53 def: "Protein SDS3_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0048390 name: SETB1_HUMAN-Phosphoserine1066 def: "Protein SETB1_HUMAN with the residue 1066 substituted with Phosphoserine" [UniProtKB:Q15047] xref: UniProtKB:Q15047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:B0048391 name: SGOL1_HUMAN-Phosphoserine436 def: "Protein SGOL1_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q5FBB7] xref: UniProtKB:Q5FBB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001847 ! SGOL1_HUMAN [Term] id: CCO:B0048392 name: SIPA1_HUMAN-Phosphoserine839 def: "Protein SIPA1_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:Q96FS4] xref: UniProtKB:Q96FS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002039 ! SIPA1_HUMAN [Term] id: CCO:B0048393 name: SKP2_HUMAN-Phosphoserine179 def: "Protein SKP2_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q13309] xref: UniProtKB:Q13309 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:B0048394 name: SMAD3_HUMAN-Phosphoserine423 def: "Protein SMAD3_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:P84022] comment: By similarity xref: UniProtKB:P84022 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:B0048395 name: SMAD3_HUMAN-Phosphoserine425 def: "Protein SMAD3_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:P84022] comment: By similarity xref: UniProtKB:P84022 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:B0048396 name: SMRC1_HUMAN-N-acetylalanine2 def: "Protein SMRC1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0048397 name: SNAPN_HUMAN-Phosphoserine50 def: "Protein SNAPN_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:O95295] comment: by PKA; By similarity xref: UniProtKB:O95295 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043870 ! SNAPN_HUMAN [Term] id: CCO:B0048398 name: SNAPN_HUMAN-Phosphoserine133 def: "Protein SNAPN_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:O95295] xref: UniProtKB:O95295 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000027 ! SNARE binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0043870 ! SNAPN_HUMAN [Term] id: CCO:B0048399 name: SPIN1_HUMAN-Phosphotyrosine91 def: "Protein SPIN1_HUMAN with the residue 91 substituted with Phosphotyrosine" [UniProtKB:Q9Y657] xref: UniProtKB:Q9Y657 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002262 ! SPIN1_HUMAN [Term] id: CCO:B0048400 name: SPIN1_HUMAN-Phosphotyrosine98 def: "Protein SPIN1_HUMAN with the residue 98 substituted with Phosphotyrosine" [UniProtKB:Q9Y657] xref: UniProtKB:Q9Y657 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000388 ! spindle relationship: transformation_of CCO:B0002262 ! SPIN1_HUMAN [Term] id: CCO:B0048401 name: STK4_HUMAN-N-acetylmethionine1 def: "Protein STK4_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q13043] xref: UniProtKB:Q13043 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005702 ! STK4_HUMAN [Term] id: CCO:B0048402 name: SYFB_HUMAN-Phosphotyrosine63 def: "Protein SYFB_HUMAN with the residue 63 substituted with Phosphotyrosine" [UniProtKB:Q9NSD9] xref: UniProtKB:Q9NSD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005753 ! SYFB_HUMAN [Term] id: CCO:B0048403 name: SYFB_HUMAN-Phosphotyrosine72 def: "Protein SYFB_HUMAN with the residue 72 substituted with Phosphotyrosine" [UniProtKB:Q9NSD9] xref: UniProtKB:Q9NSD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005753 ! SYFB_HUMAN [Term] id: CCO:B0048404 name: TAB1_HUMAN-Phosphoserine7 def: "Protein TAB1_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q15750] xref: UniProtKB:Q15750 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0004132 ! kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005531 ! TAB1_HUMAN [Term] id: CCO:B0048405 name: TBX3_HUMAN-Phosphoserine432 def: "Protein TBX3_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:O15119] xref: UniProtKB:O15119 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003207 ! general transcriptional repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001365 ! TBX3_HUMAN [Term] id: CCO:B0048406 name: TBX3_HUMAN-Phosphoserine438 def: "Protein TBX3_HUMAN with the residue 438 substituted with Phosphoserine" [UniProtKB:O15119] xref: UniProtKB:O15119 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001365 ! TBX3_HUMAN [Term] id: CCO:B0048407 name: TBX3_HUMAN-Phosphothreonine441 def: "Protein TBX3_HUMAN with the residue 441 substituted with Phosphothreonine" [UniProtKB:O15119] xref: UniProtKB:O15119 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001365 ! TBX3_HUMAN [Term] id: CCO:B0048408 name: TCPG_HUMAN-N-acetylmethionine1 def: "Protein TCPG_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P49368] xref: UniProtKB:P49368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005253 ! TCPG_HUMAN [Term] id: CCO:B0048409 name: TF3C1_HUMAN-Phosphoserine1856 def: "Protein TF3C1_HUMAN with the residue 1856 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0048410 name: TIF1B_HUMAN-Phosphoserine45 def: "Protein TIF1B_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0048411 name: TIF1B_HUMAN-Phosphoserine49 def: "Protein TIF1B_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0048412 name: TITIN_HUMAN-Phosphotyrosine8490 def: "Protein TITIN_HUMAN with the residue 8490 substituted with Phosphotyrosine" [UniProtKB:Q8WZ42] xref: UniProtKB:Q8WZ42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:B0048413 name: TLE3_HUMAN-Phosphoserine317 def: "Protein TLE3_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0048414 name: TNNT1_HUMAN-Phosphotyrosine164 def: "Protein TNNT1_HUMAN with the residue 164 substituted with Phosphotyrosine" [UniProtKB:P13805] xref: UniProtKB:P13805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043421 ! TNNT1_HUMAN [Term] id: CCO:B0048415 name: TP53B_HUMAN-Phosphoserine1462 def: "Protein TP53B_HUMAN with the residue 1462 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0048416 name: TRIM9_HUMAN-Phosphoserine46 def: "Protein TRIM9_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:Q9C026] xref: UniProtKB:Q9C026 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043426 ! TRIM9_HUMAN [Term] id: CCO:B0048417 name: TSC2_HUMAN-Phosphoserine1097 def: "Protein TSC2_HUMAN with the residue 1097 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0048418 name: TSC2_HUMAN-Phosphoserine1155 def: "Protein TSC2_HUMAN with the residue 1155 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0048419 name: U119A_HUMAN-Phosphoserine37 def: "Protein U119A_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q13432] comment: By similarity xref: UniProtKB:Q13432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:B0048420 name: UTP18_HUMAN-Phosphoserine205 def: "Protein UTP18_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:Q9Y5J1] xref: UniProtKB:Q9Y5J1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:B0048421 name: UTP18_HUMAN-Phosphoserine206 def: "Protein UTP18_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q9Y5J1] xref: UniProtKB:Q9Y5J1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:B0048422 name: VINC_HUMAN-Phosphotyrosine100 def: "Protein VINC_HUMAN with the residue 100 substituted with Phosphotyrosine" [UniProtKB:P18206] comment: By similarity xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0048423 name: VINC_HUMAN-Phosphotyrosine1133 def: "Protein VINC_HUMAN with the residue 1133 substituted with Phosphotyrosine" [UniProtKB:P18206] comment: by SRC-type Tyr-kinases; xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0048424 name: WDR47_HUMAN-Phosphothreonine542 def: "Protein WDR47_HUMAN with the residue 542 substituted with Phosphothreonine" [UniProtKB:O94967] xref: UniProtKB:O94967 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006319 ! WDR47_HUMAN [Term] id: CCO:B0048425 name: WDR62_HUMAN-Phosphoserine1248 def: "Protein WDR62_HUMAN with the residue 1248 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0048426 name: WDR62_HUMAN-Phosphoserine1249 def: "Protein WDR62_HUMAN with the residue 1249 substituted with Phosphoserine" [UniProtKB:O43379] xref: UniProtKB:O43379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:B0048427 name: ZN830_HUMAN-Phosphoserine89 def: "Protein ZN830_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q96NB3] xref: UniProtKB:Q96NB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002051 ! ZN830_HUMAN [Term] id: CCO:B0048428 name: ZN830_HUMAN-Phosphoserine351 def: "Protein ZN830_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q96NB3] xref: UniProtKB:Q96NB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002051 ! ZN830_HUMAN [Term] id: CCO:B0048429 name: ZN830_HUMAN-Phosphoserine362 def: "Protein ZN830_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q96NB3] xref: UniProtKB:Q96NB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002051 ! ZN830_HUMAN [Term] id: CCO:B0048430 name: ZYX_HUMAN-Phosphoserine313 def: "Protein ZYX_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0048431 name: ZZEF1_HUMAN-Phosphotyrosine976 def: "Protein ZZEF1_HUMAN with the residue 976 substituted with Phosphotyrosine" [UniProtKB:O43149] xref: UniProtKB:O43149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001380 ! ZZEF1_HUMAN [Term] id: CCO:B0048483 name: T2AG_HUMAN def: "Transcription initiation factor IIA subunit 2" [UniProtKB:P52657] synonym: "General transcription factor IIA subunit 2" EXACT [UniProtKB:P52657] synonym: "TFIIA p12 subunit" EXACT [UniProtKB:P52657] synonym: "TFIIA-12" EXACT [UniProtKB:P52657] synonym: "TFIIA-gamma" EXACT [UniProtKB:P52657] synonym: "TFIIAS" EXACT [UniProtKB:P52657] synonym: "Transcription initiation factor IIA gamma chain" EXACT [UniProtKB:P52657] xref: EMBL:AAA64951.1 xref: EMBL:AAB58247.1 xref: EMBL:AAH00287.1 xref: EMBL:AAH01919.1 xref: EMBL:AAP36026.1 xref: EMBL:CAA57357.1 xref: EMBL:CAG46989.1 xref: EMBL:EAW77573.1 xref: UniProtKB:P52657 xref: UniProtKB:Q6FGB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015029 ! GTF2A2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000276 ! transcription factor TFIIA complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0048570 name: Q6I9S2_HUMAN def: "SNW1 protein" [UniProtKB:Q6I9S2] xref: EMBL:CAG33714.1 xref: UniProtKB:Q6I9S2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015012 ! SNW1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019529 ! ascc2-snw1 physical interaction [Term] id: CCO:B0048571 name: SNW1_HUMAN def: "SNW domain-containing protein 1" [UniProtKB:Q13573] synonym: "Nuclear protein SkiP" EXACT [UniProtKB:Q13573] synonym: "Nuclear receptor coactivator NCoA-62" EXACT [UniProtKB:Q13573] synonym: "Ski-interacting protein" EXACT [UniProtKB:Q13573] xref: EMBL:AAB48857.1 xref: EMBL:AAC15912.1 xref: EMBL:AAC31697.1 xref: EMBL:AAF23325.1 xref: EMBL:AAH40112.1 xref: EMBL:AAH46105.2 xref: EMBL:AAI08904.1 xref: EMBL:AAV38863.1 xref: EMBL:AAV38864.1 xref: UniProtKB:Q13483 xref: UniProtKB:Q13573 xref: UniProtKB:Q32N03 xref: UniProtKB:Q5D0D6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015012 ! SNW1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0015948 ! skiip-ncor2-1 physical interaction relationship: participates_in CCO:I0015949 ! skiip-ncor2-2 physical interaction relationship: participates_in CCO:I0017378 ! rbpsuh-skiip-3 physical interaction relationship: participates_in CCO:I0017880 ! rbpsuh-skiip-2 physical interaction relationship: participates_in CCO:I0018654 ! notch1-skip-1 physical interaction relationship: participates_in CCO:I0018834 ! rbpsuh-skiip-1 physical interaction relationship: participates_in CCO:I0019258 ! notch1-skiip-1 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0052782 ! SNW1_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0052783 ! SNW1_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0052784 ! SNW1_HUMAN-Phosphoserine234 [Term] id: CCO:B0048576 name: B1AHB1_HUMAN def: "Minichromosome maintenance complex component 5 (MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae), isoform CRA_c)" [UniProtKB:B1AHB1] xref: EMBL:CAQ08829.1 xref: EMBL:EAW60062.1 xref: UniProtKB:B1AHB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005040 ! MCM5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0048582 name: ELP2_HUMAN def: "Elongator complex protein 2" [UniProtKB:Q6IA86] synonym: "ELP2" EXACT [UniProtKB:Q6IA86] synonym: "SHINC-2" EXACT [UniProtKB:Q6IA86] synonym: "STAT3-interacting protein" EXACT [UniProtKB:Q6IA86] synonym: "StIP1" EXACT [UniProtKB:Q6IA86] xref: EMBL:AAH09211.2 xref: EMBL:AAH32553.1 xref: EMBL:AAK97355.1 xref: EMBL:AAQ03093.1 xref: EMBL:BAA91874.1 xref: EMBL:BAB14193.1 xref: EMBL:BAD96511.1 xref: EMBL:CAG33550.1 xref: UniProtKB:Q53GZ0 xref: UniProtKB:Q687Y8 xref: UniProtKB:Q6IA86 xref: UniProtKB:Q8N5C2 xref: UniProtKB:Q96GV4 xref: UniProtKB:Q96PI7 xref: UniProtKB:Q9H9N0 xref: UniProtKB:Q9NV81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014710 ! ELP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003481 ! RNA polymerase II transcription elongation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: located_in CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0048588 name: ZN675_HUMAN def: "Zinc finger protein 675" [UniProtKB:Q8TD23] synonym: "TRAF6-binding zinc finger protein" EXACT [UniProtKB:Q8TD23] synonym: "TRAF6-inhibitory zinc finger protein" EXACT [UniProtKB:Q8TD23] xref: EMBL:AAK95822.1 xref: EMBL:BAC04216.1 xref: UniProtKB:Q8N211 xref: UniProtKB:Q8TD23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015094 ! ZNF675_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017371 ! traf6-tiz-3 physical interaction relationship: participates_in CCO:I0017698 ! traf6-tiz physical interaction relationship: participates_in CCO:I0018618 ! traf6-tiz-2 colocalization relationship: participates_in CCO:I0019494 ! traf6-tiz-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002485 ! negative regulation of osteoclast differentiation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002690 ! negative regulation of JNK cascade [Term] id: CCO:B0048590 name: ZNF98_HUMAN def: "Zinc finger protein 98" [UniProtKB:A6NK75] synonym: "Zinc finger protein F7175" EXACT [UniProtKB:A6NK75] xref: EMBL:AAI10577.1 xref: EMBL:AAI29811.1 xref: UniProtKB:A6NK75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015098 ! ZNF98_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0048591 name: Q4G131_HUMAN def: "ZNF100 protein" [UniProtKB:Q4G131] xref: EMBL:AAH31248.1 xref: UniProtKB:Q4G131 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011747 ! ZNF100_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0048593 name: ZN714_HUMAN def: "Zinc finger protein 714" [UniProtKB:Q96N38] xref: EMBL:AAH37782.1 xref: EMBL:AAH50468.2 xref: EMBL:BAB71072.1 xref: EMBL:CAD39077.1 xref: UniProtKB:Q49AI1 xref: UniProtKB:Q86W65 xref: UniProtKB:Q8ND40 xref: UniProtKB:Q96N38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011867 ! ZNF714_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0048595 name: ZN737_HUMAN def: "Zinc finger protein 737" [UniProtKB:O75373] synonym: "Zinc finger protein 102" EXACT [UniProtKB:O75373] xref: EMBL:AAC25694.1 xref: UniProtKB:O75373 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015095 ! ZNF737_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0048650 name: PO4F1_HUMAN def: "POU domain, class 4, transcription factor 1" [UniProtKB:Q01851] synonym: "Brain-specific homeobox/POU domain protein 3A" EXACT [UniProtKB:Q01851] synonym: "Brn-3A" EXACT [UniProtKB:Q01851] synonym: "Homeobox/POU domain protein RDC-1" EXACT [UniProtKB:Q01851] synonym: "Oct-T1" EXACT [UniProtKB:Q01851] xref: EMBL:AAA57161.1 xref: EMBL:AAA65605.1 xref: EMBL:CAA45907.1 xref: EMBL:CAI15184.1 xref: EMBL:EAW80585.1 xref: UniProtKB:Q01851 xref: UniProtKB:Q14986 xref: UniProtKB:Q15318 xref: UniProtKB:Q5T227 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014933 ! POU4F1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048651 name: PO4F3_HUMAN def: "POU domain, class 4, transcription factor 3" [UniProtKB:Q15319] synonym: "Brain-specific homeobox/POU domain protein 3C" EXACT [UniProtKB:Q15319] synonym: "Brn-3C" EXACT [UniProtKB:Q15319] xref: EMBL:AAA57160.1 xref: EMBL:AAC06203.1 xref: EMBL:AAI04924.1 xref: EMBL:AAI12208.1 xref: UniProtKB:O60557 xref: UniProtKB:Q15319 xref: UniProtKB:Q2M3F8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014934 ! POU4F3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048652 name: PIT1_HUMAN def: "Pituitary-specific positive transcription factor 1" [UniProtKB:P28069] synonym: "GHF-1" EXACT [UniProtKB:P28069] synonym: "Growth hormone factor 1" EXACT [UniProtKB:P28069] synonym: "Pit-1" EXACT [UniProtKB:P28069] xref: EMBL:AAA60093.1 xref: EMBL:BAA01068.1 xref: EMBL:BAA02291.1 xref: EMBL:BAA34536.1 xref: EMBL:CAA44295.1 xref: EMBL:CAA51017.1 xref: EMBL:CAA54440.1 xref: EMBL:CAA54441.1 xref: UniProtKB:O75757 xref: UniProtKB:P28069 xref: UniProtKB:Q15132 xref: UniProtKB:Q15133 xref: UniProtKB:Q9UEL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014925 ! POU1F1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0048653 name: PO5L1_HUMAN def: "Putative POU domain, class 5, transcription factor 1-like protein 1" [UniProtKB:Q06416] synonym: "Octamer-binding protein 3-like" EXACT [UniProtKB:Q06416] xref: EMBL:AAG53083.1 xref: EMBL:AAG53085.1 xref: EMBL:CAA77953.1 xref: UniProtKB:Q06416 xref: UniProtKB:Q9BZV7 xref: UniProtKB:Q9BZV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014937 ! POU5F1P1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048655 name: PO3F2_HUMAN def: "POU domain, class 3, transcription factor 2" [UniProtKB:P20265] synonym: "Brain-2" EXACT [UniProtKB:P20265] synonym: "Brain-specific homeobox/POU domain protein 2" EXACT [UniProtKB:P20265] synonym: "Nervous system-specific octamer-binding transcription factor N-Oct-3" EXACT [UniProtKB:P20265] synonym: "Protein Brn-2" EXACT [UniProtKB:P20265] xref: EMBL:AAB59611.1 xref: EMBL:AAH51699.2 xref: EMBL:CAA77990.1 xref: EMBL:CAB37982.1 xref: UniProtKB:P20265 xref: UniProtKB:Q14960 xref: UniProtKB:Q86V54 xref: UniProtKB:Q9UJL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014931 ! POU3F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002409 ! regulation of cell differentiation relationship: participates_in CCO:P0002948 ! regulation of axonogenesis [Term] id: CCO:B0048656 name: PO5F1_HUMAN def: "POU domain, class 5, transcription factor 1" [UniProtKB:Q01860] synonym: "Oct-3" EXACT [UniProtKB:Q01860] synonym: "Oct-4" EXACT [UniProtKB:Q01860] synonym: "Octamer-binding transcription factor 3" EXACT [UniProtKB:Q01860] xref: EMBL:AAB35990.1 xref: EMBL:AAI17436.1 xref: EMBL:AAI17438.1 xref: EMBL:BAB63311.1 xref: EMBL:BAC54946.1 xref: EMBL:BAE78630.1 xref: EMBL:BAF31281.1 xref: EMBL:CAA77951.1 xref: EMBL:CAA77952.1 xref: EMBL:CAA79974.1 xref: EMBL:CAA79975.1 xref: EMBL:CAI17407.1 xref: EMBL:CAI17408.1 xref: EMBL:CAI18331.1 xref: EMBL:CAI18485.1 xref: EMBL:CAI18486.1 xref: EMBL:CAI18708.1 xref: EMBL:CAI18709.1 xref: EMBL:CAQ07092.1 xref: EMBL:CAQ07093.1 xref: EMBL:CAQ09226.1 xref: EMBL:CAQ09227.1 xref: EMBL:CAQ10780.1 xref: EMBL:CAQ10781.1 xref: EMBL:EAX03367.1 xref: EMBL:EAX03368.1 xref: UniProtKB:A6NCS1 xref: UniProtKB:A6NLL8 xref: UniProtKB:P31359 xref: UniProtKB:Q01860 xref: UniProtKB:Q15167 xref: UniProtKB:Q15168 xref: UniProtKB:Q16422 xref: UniProtKB:Q5STF3 xref: UniProtKB:Q5STF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014935 ! POU5F1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016240 ! foxd3-pou5f1-1 physical interaction relationship: participates_in CCO:I0016241 ! foxd3-pou5f1-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048659 name: Q5TAG2_HUMAN def: "POU class 3 homeobox 1 (POU domain, class 3, transcription factor 1)" [UniProtKB:Q5TAG2] xref: EMBL:CAI23136.1 xref: EMBL:EAX07298.1 xref: UniProtKB:Q5TAG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014930 ! POU3F1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048661 name: PO3F4_HUMAN def: "POU domain, class 3, transcription factor 4" [UniProtKB:P49335] synonym: "Brain-4" EXACT [UniProtKB:P49335] synonym: "Brain-specific homeobox/POU domain protein 4" EXACT [UniProtKB:P49335] synonym: "Brn-4" EXACT [UniProtKB:P49335] xref: EMBL:CAA57767.1 xref: EMBL:CAI42602.1 xref: UniProtKB:P49335 xref: UniProtKB:Q5H9G9 xref: UniProtKB:Q99410 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014932 ! POU3F4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048662 name: PO5F2_HUMAN def: "POU domain, class 5, transcription factor 2" [UniProtKB:Q8N7G0] synonym: "Sperm 1 POU domain transcription factor" EXACT [UniProtKB:Q8N7G0] synonym: "SPRM-1" EXACT [UniProtKB:Q8N7G0] xref: EMBL:AAH29532.2 xref: EMBL:BAC05328.1 xref: EMBL:CAA79976.1 xref: EMBL:CAE46012.1 xref: UniProtKB:Q15169 xref: UniProtKB:Q6MZL7 xref: UniProtKB:Q8N748 xref: UniProtKB:Q8N7G0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014936 ! POU5F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048672 name: Q2VIK6_HUMAN def: "POU domain transcription factor Oct-4" [UniProtKB:Q2VIK6] synonym: "RcPOU5F1" EXACT [UniProtKB:Q2VIK6] xref: EMBL:ABB92462.1 xref: EMBL:ABF29403.1 xref: UniProtKB:Q2VIK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014935 ! POU5F1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048676 name: TCP4_HUMAN def: "Activated RNA polymerase II transcriptional coactivator p15" [UniProtKB:P53999] synonym: "p14" EXACT [UniProtKB:P53999] synonym: "PC4" EXACT [UniProtKB:P53999] synonym: "Positive cofactor 4" EXACT [UniProtKB:P53999] synonym: "SUB1 homolog" EXACT [UniProtKB:P53999] xref: EMBL:AAA20980.1 xref: EMBL:AAH09610.1 xref: EMBL:AAH10537.1 xref: EMBL:AAH18189.1 xref: EMBL:AAH22339.1 xref: EMBL:CAA56200.1 xref: UniProtKB:P53999 xref: UniProtKB:Q96L29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015031 ! SUB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019314 ! sub1-cstf2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0052816 ! TCP4_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0052817 ! TCP4_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0052818 ! TCP4_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0052819 ! TCP4_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0052820 ! TCP4_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0052821 ! TCP4_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0052822 ! TCP4_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0052823 ! TCP4_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0052824 ! TCP4_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0052825 ! TCP4_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0052826 ! TCP4_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0052827 ! TCP4_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0071287 ! TCP4_HUMAN-Phosphoserine118 [Term] id: CCO:B0048735 name: PM2L5_HUMAN def: "Postmeiotic segregation increased 2-like protein 5" [UniProtKB:A8MQ11] xref: UniProtKB:A8MQ11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011846 ! PMS2L5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0048868 name: CRIP2_HUMAN def: "Cysteine-rich protein 2" [UniProtKB:P52943] synonym: "CRP2" EXACT [UniProtKB:P52943] synonym: "Protein ESP1" EXACT [UniProtKB:P52943] xref: EMBL:AAB03194.1 xref: EMBL:AAH00434.1 xref: EMBL:AAH01931.1 xref: EMBL:AAH34151.1 xref: EMBL:AAV38714.1 xref: EMBL:BAA07703.1 xref: UniProtKB:P52943 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014687 ! CRIP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018922 ! atn1-crip2 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0064468 ! CRIP2_HUMAN-Phosphotyrosine77 [Term] id: CCO:B0048870 name: CRIP1_HUMAN def: "Cysteine-rich protein 1" [UniProtKB:P50238] synonym: "CRIP" EXACT [UniProtKB:P50238] synonym: "Cysteine-rich heart protein" EXACT [UniProtKB:P50238] synonym: "Cysteine-rich intestinal protein" EXACT [UniProtKB:P50238] synonym: "hCRHP" EXACT [UniProtKB:P50238] xref: EMBL:AAA64537.1 xref: EMBL:AAB61158.1 xref: EMBL:AAH02738.1 xref: UniProtKB:P50238 xref: UniProtKB:Q13628 xref: UniProtKB:Q96J34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014686 ! CRIP1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019962 ! crip1-hap1 physical interaction relationship: participates_in CCO:I0019963 ! crip1-sh3gl3 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0048872 name: ALS_HUMAN def: "Insulin-like growth factor-binding protein complex acid labile chain precursor" [UniProtKB:P35858] synonym: "ALS" EXACT [UniProtKB:P35858] xref: EMBL:AAA36047.1 xref: EMBL:AAF06774.1 xref: EMBL:CAC36078.1 xref: UniProtKB:P35858 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014623 ! IGFALS_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0001648 ! insulin-like growth factor ternary complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0048883 name: TAD2A_HUMAN def: "Transcriptional adapter 2-alpha" [UniProtKB:O75478] synonym: "ADA2-like protein" EXACT [UniProtKB:O75478] synonym: "Transcriptional adapter 2-like" EXACT [UniProtKB:O75478] xref: EMBL:AAC26659.1 xref: EMBL:AAC39902.1 xref: EMBL:AAH11753.1 xref: UniProtKB:A8MVD0 xref: UniProtKB:O75478 xref: UniProtKB:Q9UCW2 xref: UniProtKB:Q9UP49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004028 ! TADA2L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0048898 name: RGPS1_HUMAN def: "Ras-specific guanine nucleotide-releasing factor RalGPS1" [UniProtKB:Q5JS13] synonym: "Ral GEF with PH domain and SH3-binding motif 1" EXACT [UniProtKB:Q5JS13] synonym: "RalA exchange factor RalGPS1" EXACT [UniProtKB:Q5JS13] xref: EMBL:AAF65253.1 xref: EMBL:AAH19329.1 xref: EMBL:AAH32372.1 xref: EMBL:AAH33708.1 xref: EMBL:BAA20808.2 xref: EMBL:CAH72699.1 xref: EMBL:CAH72700.1 xref: EMBL:CAH72701.1 xref: EMBL:CAH72702.1 xref: EMBL:CAI39718.1 xref: EMBL:CAI39719.1 xref: EMBL:CAI39720.1 xref: EMBL:CAI39721.1 xref: EMBL:CAI39723.1 xref: EMBL:CAI40638.1 xref: EMBL:CAI40639.1 xref: EMBL:CAI40640.1 xref: EMBL:CAI40641.1 xref: EMBL:CAI40643.1 xref: EMBL:CAI40644.1 xref: EMBL:CAI41460.1 xref: EMBL:CAI41461.1 xref: EMBL:EAW87645.1 xref: EMBL:EAW87646.1 xref: EMBL:EAW87648.1 xref: UniProtKB:O15059 xref: UniProtKB:Q5JS13 xref: UniProtKB:Q5JT60 xref: UniProtKB:Q5JT65 xref: UniProtKB:Q5JUG5 xref: UniProtKB:Q8N4S6 xref: UniProtKB:Q8N5H4 xref: UniProtKB:Q8WUV7 xref: UniProtKB:Q9NZ16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011831 ! RALGPS1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0048923 name: B1AKC9_HUMAN def: "Ephrin receptor" [UniProtKB:B1AKC9] synonym: "EC 2.7.10.1" EXACT [UniProtKB:B1AKC9] xref: EMBL:CAI16427.1 xref: EMBL:CAI22644.1 xref: UniProtKB:B1AKC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004574 ! EPHB2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0048930 name: RICTR_HUMAN def: "Rapamycin-insensitive companion of mTOR" [UniProtKB:Q6R327] xref: EMBL:AAH51729.1 xref: EMBL:AAS79796.1 xref: EMBL:BAC02708.1 xref: EMBL:CAD39155.1 xref: EMBL:CAH18135.1 xref: EMBL:EAW55980.1 xref: UniProtKB:Q68DT5 xref: UniProtKB:Q6R327 xref: UniProtKB:Q86UB7 xref: UniProtKB:Q8N3A0 xref: UniProtKB:Q8NCM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014976 ! RICTOR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003157 ! regulation of protein kinase B signaling cascade relationship: transforms_into CCO:B0052687 ! RICTR_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0052688 ! RICTR_HUMAN-Phosphothreonine1295 relationship: transforms_into CCO:B0070021 ! RICTR_HUMAN-Phosphoserine1282 relationship: transforms_into CCO:B0070022 ! RICTR_HUMAN-Phosphotyrosine1386 relationship: transforms_into CCO:B0070023 ! RICTR_HUMAN-Phosphoserine1388 relationship: transforms_into CCO:B0070024 ! RICTR_HUMAN-Phosphoserine1396 [Term] id: CCO:B0048954 name: IL31R_HUMAN def: "Interleukin-31 receptor A precursor" [UniProtKB:Q8NI17] synonym: "Cytokine receptor-like 3" EXACT [UniProtKB:Q8NI17] synonym: "GLM-R" EXACT [UniProtKB:Q8NI17] synonym: "Gp130-like monocyte receptor" EXACT [UniProtKB:Q8NI17] synonym: "Gp130-like receptor" EXACT [UniProtKB:Q8NI17] synonym: "HGLM-R" EXACT [UniProtKB:Q8NI17] synonym: "IL-31RA" EXACT [UniProtKB:Q8NI17] xref: EMBL:AAI10491.1 xref: EMBL:AAL36452.1 xref: EMBL:AAM27958.1 xref: EMBL:AAQ88484.1 xref: EMBL:AAQ89100.1 xref: EMBL:AAS86444.1 xref: EMBL:AAS86445.1 xref: EMBL:AAS86446.1 xref: EMBL:AAS86447.1 xref: UniProtKB:A6NIF8 xref: UniProtKB:Q2TBA1 xref: UniProtKB:Q6EBC3 xref: UniProtKB:Q6EBC4 xref: UniProtKB:Q6EBC5 xref: UniProtKB:Q6EBC6 xref: UniProtKB:Q6UWL8 xref: UniProtKB:Q8NI17 xref: UniProtKB:Q8WYJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014776 ! IL31RA_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004221 ! cytokine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002082 ! positive regulation of tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002088 ! positive regulation of tyrosine phosphorylation of Stat5 protein relationship: participates_in CCO:P0002143 ! negative regulation of macrophage activation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0048975 name: TGM2_HUMAN def: "Protein-glutamine gamma-glutamyltransferase 2" [UniProtKB:P21980] synonym: "EC 2.3.2.13" EXACT [UniProtKB:P21980] synonym: "TG(C)" EXACT [UniProtKB:P21980] synonym: "TGase C" EXACT [UniProtKB:P21980] synonym: "TGase-H" EXACT [UniProtKB:P21980] synonym: "TGC" EXACT [UniProtKB:P21980] synonym: "Tissue transglutaminase" EXACT [UniProtKB:P21980] synonym: "Transglutaminase-2" EXACT [UniProtKB:P21980] xref: EMBL:AAA36739.1 xref: EMBL:AAA63261.1 xref: EMBL:AAB36379.1 xref: EMBL:AAH03551.1 xref: EMBL:CAB66115.1 xref: UniProtKB:P21980 xref: UniProtKB:Q16436 xref: UniProtKB:Q9BTN7 xref: UniProtKB:Q9UH35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015039 ! TGM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007446 ! cdh1-ctnna1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0003100 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: transforms_into CCO:B0052833 ! TGM2_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0052834 ! TGM2_HUMAN-Phosphotyrosine369 relationship: transforms_into CCO:B0052835 ! TGM2_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0071376 ! TGM2_HUMAN-Phosphotyrosine219 [Term] id: CCO:B0049000 name: Q59EX1_HUMAN def: "ADAM 32 (A disintegrin and metalloprotease domain 32) variant" [UniProtKB:Q59EX1] xref: EMBL:BAD92927.1 xref: UniProtKB:Q59EX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0049019 name: IGHM_HUMAN def: "Ig mu chain C region" [UniProtKB:P01871] xref: EMBL:AAB59422.1 xref: EMBL:CAA33065.1 xref: EMBL:CAA33069.1 xref: EMBL:CAA33070.1 xref: EMBL:CAA33071.1 xref: EMBL:CAA34971.1 xref: EMBL:CAB37838.1 xref: EMBL:CAE82013.1 xref: EMBL:CAE82014.1 xref: UniProtKB:P01871 xref: UniProtKB:P20769 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008799 ! IGHM_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000889 ! B cell receptor complex relationship: located_in CCO:C0001650 ! immunoglobulin complex, circulating relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0017533 ! ighm-ubqln4 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0002557 ! positive regulation of endocytosis relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway [Term] id: CCO:B0049025 name: O95973_HUMAN def: "VH4 heavy chain variable region precursor" [UniProtKB:O95973] xref: EMBL:AAC79084.1 xref: UniProtKB:O95973 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015148 ! IGM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018217 ! z39ig-c3 physical interaction [Term] id: CCO:B0049067 name: HNF6_HUMAN def: "Hepatocyte nuclear factor 6" [UniProtKB:Q9UBC0] synonym: "HNF-6" EXACT [UniProtKB:Q9UBC0] synonym: "One cut domain family member 1" EXACT [UniProtKB:Q9UBC0] xref: EMBL:AAB61705.1 xref: EMBL:AAD00826.1 xref: EMBL:AAD02033.1 xref: EMBL:CAB50769.1 xref: UniProtKB:Q99744 xref: UniProtKB:Q9UBC0 xref: UniProtKB:Q9UMR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014769 ! ONECUT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049069 name: ONEC3_HUMAN def: "One cut domain family member 3" [UniProtKB:O60422] synonym: "OC-3" EXACT [UniProtKB:O60422] synonym: "One cut homeobox 3" EXACT [UniProtKB:O60422] synonym: "Transcription factor ONECUT-3" EXACT [UniProtKB:O60422] xref: EMBL:AAC17602.1 xref: UniProtKB:O60422 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014872 ! ONECUT3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049070 name: ONEC2_HUMAN def: "One cut domain family member 2" [UniProtKB:O95948] synonym: "Hepatocyte nuclear factor 6-beta" EXACT [UniProtKB:O95948] synonym: "HNF-6-beta" EXACT [UniProtKB:O95948] synonym: "OC-2" EXACT [UniProtKB:O95948] synonym: "Transcription factor ONECUT-2" EXACT [UniProtKB:O95948] xref: EMBL:CAB38253.1 xref: UniProtKB:O95948 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014871 ! ONECUT2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049072 name: FOXS1_HUMAN def: "Forkhead box protein S1" [UniProtKB:O43638] synonym: "Forkhead-like 18 protein" EXACT [UniProtKB:O43638] synonym: "Forkhead-related transcription factor 10" EXACT [UniProtKB:O43638] synonym: "FREAC-10" EXACT [UniProtKB:O43638] xref: EMBL:AAC15420.1 xref: EMBL:AAH13408.1 xref: EMBL:AAP88770.1 xref: EMBL:CAI12817.1 xref: UniProtKB:O43638 xref: UniProtKB:Q96D28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014733 ! FOXS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015001 ! fkhl18-rbpms physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049076 name: YB040_HUMAN def: "Putative forkhead box protein ENSP00000381211" [UniProtKB:A8MTJ6] xref: UniProtKB:A8MTJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049157 name: PAR4_HUMAN def: "Proteinase-activated receptor 4 precursor" [UniProtKB:Q96RI0] synonym: "Coagulation factor II receptor-like 3" EXACT [UniProtKB:Q96RI0] synonym: "PAR-4" EXACT [UniProtKB:Q96RI0] synonym: "Thrombin receptor-like 3" EXACT [UniProtKB:Q96RI0] xref: EMBL:AAC25699.1 xref: EMBL:AAC28860.1 xref: EMBL:AAH74782.2 xref: EMBL:AAK61908.1 xref: EMBL:AAR08487.1 xref: UniProtKB:O76067 xref: UniProtKB:Q6DK42 xref: UniProtKB:Q96RI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014910 ! F2RL3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002550 ! thrombin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0049159 name: Q7Z3W3_HUMAN def: "Putative uncharacterized protein DKFZp686N1782" [UniProtKB:Q7Z3W3] xref: EMBL:CAD97628.1 xref: UniProtKB:Q7Z3W3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015222 ! DKFZp686N1782_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0002550 ! thrombin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049161 name: PAR2_HUMAN def: "Proteinase-activated receptor 2 precursor" [UniProtKB:P55085] synonym: "Coagulation factor II receptor-like 1" EXACT [UniProtKB:P55085] synonym: "G-protein coupled receptor 11" EXACT [UniProtKB:P55085] synonym: "PAR-2" EXACT [UniProtKB:P55085] synonym: "Thrombin receptor-like 1" EXACT [UniProtKB:P55085] xref: EMBL:AAA90957.1 xref: EMBL:AAB47871.1 xref: EMBL:AAH12453.1 xref: EMBL:AAH18130.1 xref: EMBL:AAK77914.1 xref: EMBL:CAA90290.1 xref: UniProtKB:P55085 xref: UniProtKB:Q13317 xref: UniProtKB:Q13346 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014908 ! F2RL1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0002550 ! thrombin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049166 name: Q5T4B6_HUMAN def: "Thymosin-like 4 (HCG1780554)" [UniProtKB:Q5T4B6] xref: EMBL:CAI13489.1 xref: EMBL:EAW87781.1 xref: UniProtKB:Q5T4B6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015181 ! TMSL4_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002135 ! sequestering of actin monomers [Term] id: CCO:B0049167 name: TMSL2_HUMAN def: "Thymosin beta-4-like protein 2" [UniProtKB:Q2KHM7] xref: EMBL:AAI04197.1 xref: EMBL:AAI04198.1 xref: EMBL:AAI13077.1 xref: UniProtKB:Q2KHM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015052 ! TMSL2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0052854 ! TMSL2_HUMAN-N-acetylserine2 [Term] id: CCO:B0049174 name: TMSL1_HUMAN def: "Thymosin beta-4-like protein 1" [UniProtKB:Q08EQ4] xref: EMBL:AAI01200.1 xref: EMBL:AAI01201.1 xref: UniProtKB:Q08EQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015051 ! TMSL1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0052853 ! TMSL1_HUMAN-N-acetylserine2 [Term] id: CCO:B0049175 name: TMSL3_HUMAN def: "Thymosin beta-4-like protein 3" [UniProtKB:A8MW06] xref: UniProtKB:A8MW06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015053 ! TMSL3_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0052855 ! TMSL3_HUMAN-N-acetylserine2 [Term] id: CCO:B0049176 name: TYB4Y_HUMAN def: "Thymosin beta-4, Y-chromosomal" [UniProtKB:O14604] xref: EMBL:AAC51836.1 xref: EMBL:AAD54509.1 xref: EMBL:AAI19764.1 xref: EMBL:AAI19765.1 xref: UniProtKB:O14604 xref: UniProtKB:Q0VDA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015070 ! TMSB4Y_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0015692 ! ewsr1-tmsb4y physical interaction relationship: participates_in CCO:P0000811 ! regulation of actin polymerization and/or depolymerization relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0052885 ! TYB4Y_HUMAN-N-acetylserine2 [Term] id: CCO:B0049178 name: TYB10_HUMAN def: "Thymosin beta-10" [UniProtKB:P63313] xref: EMBL:AAA36744.1 xref: EMBL:AAA36746.1 xref: EMBL:AAB25225.1 xref: EMBL:AAC41691.1 xref: EMBL:AAH16025.1 xref: EMBL:AAH16731.1 xref: UniProtKB:P13472 xref: UniProtKB:P63313 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015069 ! TMSB10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0052883 ! TYB10_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0052884 ! TYB10_HUMAN-N6-acetyllysine4 relationship: transforms_into CCO:B0071641 ! TYB10_HUMAN-Phosphothreonine23 [Term] id: CCO:B0049179 name: TMSL6_HUMAN def: "Thymosin beta-4-like protein 6" [UniProtKB:A9Z1Y9] synonym: "Thymosin beta-4-like" EXACT [UniProtKB:A9Z1Y9] xref: EMBL:AAI12283.1 xref: UniProtKB:A9Z1Y9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015054 ! TMSL6_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0052856 ! TMSL6_HUMAN-N-acetylserine2 [Term] id: CCO:B0049259 name: B0QYS6_HUMAN def: "Transcription factor EB" [UniProtKB:B0QYS6] xref: EMBL:CAQ07961.1 xref: UniProtKB:B0QYS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015037 ! TFEB_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049260 name: TFEB_HUMAN def: "Transcription factor EB" [UniProtKB:P19484] xref: EMBL:AAA36730.1 xref: EMBL:AAH06225.2 xref: EMBL:AAH32448.1 xref: EMBL:CAD92604.1 xref: EMBL:CAE77681.1 xref: UniProtKB:P19484 xref: UniProtKB:Q709B3 xref: UniProtKB:Q7Z6P9 xref: UniProtKB:Q9BRJ5 xref: UniProtKB:Q9UJD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015037 ! TFEB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0052832 ! TFEB_HUMAN-Phosphoserine467 [Term] id: CCO:B0049261 name: B0QYS7_HUMAN def: "Transcription factor EB" [UniProtKB:B0QYS7] xref: EMBL:CAQ07962.1 xref: UniProtKB:B0QYS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015037 ! TFEB_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049262 name: TFE3_HUMAN def: "Transcription factor E3" [UniProtKB:P19532] xref: EMBL:CAA35714.1 xref: EMBL:CAA65478.1 xref: EMBL:CAA65800.1 xref: EMBL:CAA68061.1 xref: UniProtKB:A8MZL6 xref: UniProtKB:P19532 xref: UniProtKB:Q92757 xref: UniProtKB:Q92758 xref: UniProtKB:Q99964 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015036 ! TFE3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0052831 ! TFE3_HUMAN-Phosphoserine568 [Term] id: CCO:B0049263 name: B1AKB4_HUMAN def: "cDNA FLJ37742 fis, clone BRHIP2022054, highly similar to Transcription factor EB" [UniProtKB:B1AKB4] synonym: "Transcription factor EB" EXACT [UniProtKB:B1AKB4] xref: EMBL:BAG52979.1 xref: EMBL:CAI22454.1 xref: EMBL:CAO72131.1 xref: UniProtKB:B1AKB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015037 ! TFEB_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049264 name: B1AKB5_HUMAN def: "Transcription factor EB" [UniProtKB:B1AKB5] xref: EMBL:CAI22455.1 xref: UniProtKB:B1AKB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015037 ! TFEB_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049269 name: TF2H4_HUMAN def: "General transcription factor IIH subunit 4" [UniProtKB:Q92759] synonym: "Basic transcription factor 2 52 kDa subunit" EXACT [UniProtKB:Q92759] synonym: "BTF2-p52" EXACT [UniProtKB:Q92759] synonym: "General transcription factor IIH polypeptide 4" EXACT [UniProtKB:Q92759] synonym: "TFIIH basal transcription factor complex p52 subunit" EXACT [UniProtKB:Q92759] xref: EMBL:AAH04935.1 xref: EMBL:AAH16302.1 xref: EMBL:AAM64222.1 xref: EMBL:AAP35985.1 xref: EMBL:BAB63317.1 xref: EMBL:CAA68870.1 xref: UniProtKB:Q92759 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015033 ! GTF2H4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000279 ! holo TFIIH complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049297 name: PYRG2_HUMAN def: "CTP synthase 2" [UniProtKB:Q9NRF8] synonym: "CTP synthetase 2" EXACT [UniProtKB:Q9NRF8] synonym: "EC 6.3.4.2" EXACT [UniProtKB:Q9NRF8] synonym: "UTP--ammonia ligase 2" EXACT [UniProtKB:Q9NRF8] xref: EMBL:AAF91241.1 xref: EMBL:AAH06256.2 xref: EMBL:AAH34986.1 xref: EMBL:BAB14607.1 xref: EMBL:BAB14814.1 xref: EMBL:CAI40086.1 xref: UniProtKB:Q9BRI0 xref: UniProtKB:Q9H809 xref: UniProtKB:Q9H8K9 xref: UniProtKB:Q9NRF8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014970 ! CTPS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015243 ! ctps2-spg21 physical interaction relationship: transforms_into CCO:B0052677 ! PYRG2_HUMAN-Phosphoserine568 relationship: transforms_into CCO:B0052678 ! PYRG2_HUMAN-Phosphoserine571 relationship: transforms_into CCO:B0052679 ! PYRG2_HUMAN-Phosphoserine574 [Term] id: CCO:B0049305 name: TVA3_HUMAN def: "T-cell receptor alpha chain V region PY14 precursor" [UniProtKB:P01737] xref: UniProtKB:P01737 is_a: CCO:U0000007 ! cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0005647 ! MHC protein binding relationship: has_function CCO:F0005688 ! peptide antigen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0019183 ! ha-hla_dra-1 physical interaction [Term] id: CCO:B0049379 name: GNAT3_HUMAN def: "Guanine nucleotide-binding protein G(t) subunit alpha-3" [UniProtKB:A8MTJ3] synonym: "Gustducin alpha-3 chain" EXACT [UniProtKB:A8MTJ3] xref: EMBL:EAL24192.1 xref: EMBL:EAL24193.1 xref: UniProtKB:A4D1B2 xref: UniProtKB:A4D1B3 xref: UniProtKB:A8MTJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014752 ! GNAT3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049381 name: GNAO_HUMAN def: "Guanine nucleotide-binding protein G(o) subunit alpha" [UniProtKB:P09471] xref: EMBL:AAA52584.1 xref: EMBL:AAA52585.1 xref: EMBL:AAA52586.1 xref: EMBL:AAM12608.1 xref: EMBL:AAM12609.1 xref: EMBL:CAB46639.1 xref: UniProtKB:P09471 xref: UniProtKB:P29777 xref: UniProtKB:Q8TD72 xref: UniProtKB:Q9UMV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014748 ! GNAO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019965 ! dctn2-gnao1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0052410 ! GNAO_HUMAN-ADP-ribosylarginine179 relationship: transforms_into CCO:B0052411 ! GNAO_HUMAN-ADP-ribosylcysteine351 [Term] id: CCO:B0049421 name: KCNQ1_HUMAN def: "Potassium voltage-gated channel subfamily KQT member 1" [UniProtKB:P51787] synonym: "IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1" EXACT [UniProtKB:P51787] synonym: "KQT-like 1" EXACT [UniProtKB:P51787] synonym: "Voltage-gated potassium channel subunit Kv7.1" EXACT [UniProtKB:P51787] xref: EMBL:AAB53974.1 xref: EMBL:AAC05705.1 xref: EMBL:AAC51776.1 xref: EMBL:AAC51781.1 xref: EMBL:AAM94040.1 xref: EMBL:BAA34738.1 xref: EMBL:BAA34739.1 xref: EMBL:CAB44649.1 xref: EMBL:CAB44650.1 xref: UniProtKB:O00347 xref: UniProtKB:O60607 xref: UniProtKB:O94787 xref: UniProtKB:P51787 xref: UniProtKB:Q7Z6G9 xref: UniProtKB:Q92960 xref: UniProtKB:Q9UMN8 xref: UniProtKB:Q9UMN9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014795 ! KCNQ1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001519 ! delayed rectifier potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017203 ! traf6-kcnq1 physical interaction [Term] id: CCO:B0049425 name: CNTF_HUMAN def: "Ciliary neurotrophic factor" [UniProtKB:P26441] synonym: "CNTF" EXACT [UniProtKB:P26441] xref: EMBL:AAH68030.1 xref: EMBL:AAH74963.1 xref: EMBL:AAH74964.1 xref: EMBL:CAA39374.1 xref: EMBL:CAA43009.1 xref: EMBL:CAA43032.1 xref: UniProtKB:P26441 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014681 ! CNTF_human relationship: has_function CCO:F0001429 ! ciliary neurotrophic factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0049439 name: RYR2_HUMAN def: "Ryanodine receptor 2" [UniProtKB:Q92736] synonym: "Cardiac muscle ryanodine receptor-calcium release channel" EXACT [UniProtKB:Q92736] synonym: "Cardiac muscle-type ryanodine receptor" EXACT [UniProtKB:Q92736] synonym: "hRYR-2" EXACT [UniProtKB:Q92736] synonym: "RYR-2" EXACT [UniProtKB:Q92736] synonym: "RyR2" EXACT [UniProtKB:Q92736] xref: EMBL:CAA05502.1 xref: EMBL:CAA62975.1 xref: EMBL:CAA66975.1 xref: EMBL:CAA69395.1 xref: EMBL:CAC18855.1 xref: EMBL:CAH71369.1 xref: EMBL:CAH71393.1 xref: EMBL:CAH73918.1 xref: EMBL:CAI14440.1 xref: EMBL:CAI15350.1 xref: EMBL:CAI15936.1 xref: EMBL:CAI22065.1 xref: UniProtKB:Q15411 xref: UniProtKB:Q546N8 xref: UniProtKB:Q5T3P2 xref: UniProtKB:Q92736 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014989 ! RYR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000834 ! induction of apoptosis by ionic changes relationship: transforms_into CCO:B0070272 ! RYR2_HUMAN-Phosphoserine2806 [Term] id: CCO:B0049445 name: A6NEW7_HUMAN def: "Putative uncharacterized protein TACR2" [UniProtKB:A6NEW7] xref: UniProtKB:A6NEW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014850 ! TACR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001333 ! tachykinin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049448 name: Q53TQ2_HUMAN def: "Putative uncharacterized protein TACR1" [UniProtKB:Q53TQ2] xref: EMBL:AAY14950.1 xref: UniProtKB:Q53TQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014849 ! TACR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001333 ! tachykinin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049452 name: NK2R_HUMAN def: "Substance-K receptor" [UniProtKB:P21452] synonym: "Neurokinin A receptor" EXACT [UniProtKB:P21452] synonym: "NK-2 receptor" EXACT [UniProtKB:P21452] synonym: "NK-2R" EXACT [UniProtKB:P21452] synonym: "SKR" EXACT [UniProtKB:P21452] synonym: "Tachykinin receptor 2" EXACT [UniProtKB:P21452] xref: EMBL:AAA60347.1 xref: EMBL:AAB05897.1 xref: EMBL:AAC31760.1 xref: EMBL:AAP84358.1 xref: UniProtKB:P21452 xref: UniProtKB:Q9UDE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014850 ! TACR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001333 ! tachykinin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway [Term] id: CCO:B0049455 name: NK3R_HUMAN def: "Neuromedin-K receptor" [UniProtKB:P29371] synonym: "Neurokinin B receptor" EXACT [UniProtKB:P29371] synonym: "NK-3 receptor" EXACT [UniProtKB:P29371] synonym: "NK-3R" EXACT [UniProtKB:P29371] synonym: "NKR" EXACT [UniProtKB:P29371] synonym: "Tachykinin receptor 3" EXACT [UniProtKB:P29371] xref: EMBL:AAA36366.1 xref: EMBL:AAB21706.1 xref: EMBL:AAI21807.1 xref: EMBL:AAR23926.1 xref: EMBL:CAA46291.1 xref: UniProtKB:P29371 xref: UniProtKB:Q0P510 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014851 ! TACR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001333 ! tachykinin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway [Term] id: CCO:B0049457 name: NK1R_HUMAN def: "Substance-P receptor" [UniProtKB:P25103] synonym: "NK-1 receptor" EXACT [UniProtKB:P25103] synonym: "NK-1R" EXACT [UniProtKB:P25103] synonym: "SPR" EXACT [UniProtKB:P25103] synonym: "Tachykinin receptor 1" EXACT [UniProtKB:P25103] xref: EMBL:AAA36641.1 xref: EMBL:AAA36644.1 xref: EMBL:AAA59933.1 xref: EMBL:AAA59936.1 xref: EMBL:AAA60601.1 xref: EMBL:AAB20168.2 xref: EMBL:AAH74911.1 xref: EMBL:AAH74912.1 xref: EMBL:AAR23925.1 xref: EMBL:CAA46292.1 xref: UniProtKB:P25103 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014849 ! TACR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001333 ! tachykinin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway [Term] id: CCO:B0049472 name: Q9BSR4_HUMAN def: "DNA-directed RNA polymerase" [UniProtKB:Q9BSR4] synonym: "EC 2.7.7.6" EXACT [UniProtKB:Q9BSR4] xref: EMBL:AAH04882.4 xref: UniProtKB:Q9BSR4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014986 ! POLR1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017179 ! nfkbib-polr1b-1 physical interaction [Term] id: CCO:B0049473 name: RPA2_HUMAN def: "DNA-directed RNA polymerase I subunit RPA2" [UniProtKB:Q9H9Y6] synonym: "DNA-directed RNA polymerase I 135 kDa polypeptide" EXACT [UniProtKB:Q9H9Y6] synonym: "EC 2.7.7.6" EXACT [UniProtKB:Q9H9Y6] synonym: "RNA polymerase I subunit 2" EXACT [UniProtKB:Q9H9Y6] synonym: "RPA135" EXACT [UniProtKB:Q9H9Y6] xref: EMBL:AAX81999.1 xref: EMBL:BAB14082.1 xref: EMBL:BAB14296.1 xref: EMBL:BAC87247.1 xref: UniProtKB:Q585T5 xref: UniProtKB:Q6ZRR2 xref: UniProtKB:Q9H9D3 xref: UniProtKB:Q9H9Y6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014986 ! POLR1B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0016413 ! nfkbib-polr1b physical interaction relationship: participates_in CCO:I0018638 ! baz1b-polr1a colocalization relationship: participates_in CCO:I0018639 ! smarca5-polr1a colocalization [Term] id: CCO:B0049552 name: A9YLN5_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:A9YLN5] synonym: "EC 2.7.10.1" EXACT [UniProtKB:A9YLN5] xref: EMBL:ABX59672.1 xref: UniProtKB:A9YLN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015126 ! SLC34A2/ROS fusion_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0049553 name: A9YLN4_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:A9YLN4] synonym: "EC 2.7.10.1" EXACT [UniProtKB:A9YLN4] xref: EMBL:ABX59671.1 xref: UniProtKB:A9YLN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015125 ! CD74/ROS fusion_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005649 ! MHC class II protein binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0049556 name: Q5H8Y1_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:Q5H8Y1] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q5H8Y1] xref: EMBL:CAI23379.1 xref: EMBL:CAI42375.1 xref: UniProtKB:Q5H8Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014985 ! ROS1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0049557 name: A9YLN6_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:A9YLN6] synonym: "EC 2.7.10.1" EXACT [UniProtKB:A9YLN6] xref: EMBL:ABX59673.1 xref: UniProtKB:A9YLN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015127 ! SLC34A2/ROS1 fusion_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0049558 name: HG2A_HUMAN def: "HLA class II histocompatibility antigen gamma chain" [UniProtKB:P04233] synonym: "CD74 antigen" EXACT [UniProtKB:P04233] synonym: "HLA-DR antigens-associated invariant chain" EXACT [UniProtKB:P04233] synonym: "Ia antigen-associated invariant chain" EXACT [UniProtKB:P04233] synonym: "Ii" EXACT [UniProtKB:P04233] synonym: "p33" EXACT [UniProtKB:P04233] xref: EMBL:AAA36033.1 xref: EMBL:AAA36304.1 xref: EMBL:AAH18726.1 xref: EMBL:AAV38312.1 xref: EMBL:CAA25192.1 xref: EMBL:CAA25193.1 xref: EMBL:CAA27046.1 xref: EMBL:CAA27047.1 xref: UniProtKB:P04233 xref: UniProtKB:Q14597 xref: UniProtKB:Q29832 xref: UniProtKB:Q5U0J8 xref: UniProtKB:Q8WLP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014763 ! CD74_human relationship: has_function CCO:F0004221 ! cytokine binding relationship: has_function CCO:F0005649 ! MHC class II protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002142 ! regulation of macrophage activation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0049576 name: NRG1_HUMAN def: "Pro-neuregulin-1, membrane-bound isoform precursor" [UniProtKB:Q02297] synonym: "Pro-NRG1" EXACT [UniProtKB:Q02297] xref: EMBL:AAA19950.1 xref: EMBL:AAA19951.1 xref: EMBL:AAA19952.1 xref: EMBL:AAA19953.1 xref: EMBL:AAA19954.1 xref: EMBL:AAA19955.1 xref: EMBL:AAA58638.1 xref: EMBL:AAA58639.1 xref: EMBL:AAA58640.1 xref: EMBL:AAA58641.1 xref: EMBL:AAB59358.1 xref: EMBL:AAB59622.1 xref: EMBL:AAC51756.1 xref: EMBL:AAD01795.1 xref: EMBL:AAH73871.1 xref: EMBL:AAM71137.1 xref: EMBL:AAM71139.1 xref: EMBL:AAM71140.1 xref: EMBL:DAA00044.1 xref: EMBL:DAA00045.1 xref: EMBL:DAA00046.1 xref: EMBL:DAA00047.1 xref: UniProtKB:O14667 xref: UniProtKB:P98202 xref: UniProtKB:Q02297 xref: UniProtKB:Q02298 xref: UniProtKB:Q02299 xref: UniProtKB:Q07110 xref: UniProtKB:Q07111 xref: UniProtKB:Q12779 xref: UniProtKB:Q12780 xref: UniProtKB:Q12781 xref: UniProtKB:Q12782 xref: UniProtKB:Q12783 xref: UniProtKB:Q12784 xref: UniProtKB:Q7RTV9 xref: UniProtKB:Q7RTW0 xref: UniProtKB:Q7RTW1 xref: UniProtKB:Q7RTW2 xref: UniProtKB:Q8NFN1 xref: UniProtKB:Q8NFN2 xref: UniProtKB:Q8NFN3 xref: UniProtKB:Q9UPE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014858 ! NRG1_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0004384 ! transmembrane receptor protein tyrosine kinase activator activity relationship: has_function CCO:F0004611 ! receptor tyrosine kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0003052 ! positive regulation of striated muscle cell differentiation [Term] id: CCO:B0049611 name: ARP3B_HUMAN def: "Actin-related protein 3B" [UniProtKB:Q9P1U1] synonym: "Actin-like protein 3B" EXACT [UniProtKB:Q9P1U1] synonym: "Actin-related protein ARP4" EXACT [UniProtKB:Q9P1U1] synonym: "ARP3-beta" EXACT [UniProtKB:Q9P1U1] xref: EMBL:AAC98904.1 xref: EMBL:AAH08682.1 xref: EMBL:AAP97150.1 xref: EMBL:BAG37914.1 xref: UniProtKB:Q7Z526 xref: UniProtKB:Q9P1U1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008904 ! ACTR3B_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: transforms_into CCO:B0052287 ! ARP3B_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0052288 ! ARP3B_HUMAN-Phosphotyrosine231 relationship: transforms_into CCO:B0052289 ! ARP3B_HUMAN-Phosphoserine418 [Term] id: CCO:B0049672 name: TPO_HUMAN def: "Thrombopoietin precursor" [UniProtKB:P40225] synonym: "C-mpl ligand" EXACT [UniProtKB:P40225] synonym: "Megakaryocyte colony-stimulating factor" EXACT [UniProtKB:P40225] synonym: "Megakaryocyte growth and development factor" EXACT [UniProtKB:P40225] synonym: "MGDF" EXACT [UniProtKB:P40225] synonym: "ML" EXACT [UniProtKB:P40225] synonym: "Myeloproliferative leukemia virus oncogene ligand" EXACT [UniProtKB:P40225] xref: EMBL:AAA50553.1 xref: EMBL:AAA59857.1 xref: EMBL:AAA74083.1 xref: EMBL:AAB03392.1 xref: EMBL:AAB03393.1 xref: EMBL:AAB03394.1 xref: EMBL:AAB33390.1 xref: EMBL:AAC37566.1 xref: EMBL:AAC37568.1 xref: EMBL:BAA06807.1 xref: EMBL:BAA21930.1 xref: UniProtKB:P40225 xref: UniProtKB:Q13020 xref: UniProtKB:Q15790 xref: UniProtKB:Q15791 xref: UniProtKB:Q15792 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015057 ! THPO_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0049674 name: Q5FBX8_HUMAN def: "Thrombopoietin nirs variant 1" [UniProtKB:Q5FBX8] xref: EMBL:BAD89419.1 xref: UniProtKB:Q5FBX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015057 ! THPO_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0049686 name: ATX3L_HUMAN def: "Putative ataxin-3-like protein" [UniProtKB:Q9H3M9] synonym: "EC 3.4.22.-" EXACT [UniProtKB:Q9H3M9] synonym: "Machado-Joseph disease protein 1-like" EXACT [UniProtKB:Q9H3M9] xref: EMBL:BAB18799.1 xref: UniProtKB:Q9H3M9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014638 ! ATXN3L_human relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049689 name: ATX3_HUMAN def: "Ataxin-3" [UniProtKB:P54252] synonym: "EC 3.4.22.-" EXACT [UniProtKB:P54252] synonym: "Machado-Joseph disease protein 1" EXACT [UniProtKB:P54252] synonym: "Spinocerebellar ataxia type 3 protein" EXACT [UniProtKB:P54252] xref: EMBL:AAB33571.1 xref: EMBL:AAB63352.1 xref: EMBL:AAB63353.1 xref: EMBL:AAB63354.1 xref: EMBL:AAH33711.1 xref: EMBL:ABS29269.1 xref: EMBL:BAB18798.1 xref: EMBL:BAB55645.1 xref: EMBL:BAB55646.1 xref: EMBL:EAW81472.1 xref: UniProtKB:A7LFZ5 xref: UniProtKB:O15284 xref: UniProtKB:O15285 xref: UniProtKB:O15286 xref: UniProtKB:P54252 xref: UniProtKB:Q8N189 xref: UniProtKB:Q96TC3 xref: UniProtKB:Q96TC4 xref: UniProtKB:Q9H3N0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014639 ! ATXN3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:I0017571 ! ewsr1-atxn3 physical interaction relationship: participates_in CCO:I0017614 ! atxn3-rad23a physical interaction relationship: participates_in CCO:I0017615 ! atxn3-rad23b physical interaction relationship: participates_in CCO:I0019123 ! atxn3-prkcabp physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052301 ! ATX3_HUMAN-Phosphoserine219 [Term] id: CCO:B0049698 name: CLD7_HUMAN def: "Claudin-7" [UniProtKB:O95471] synonym: "CLDN-7" EXACT [UniProtKB:O95471] xref: EMBL:AAH01055.1 xref: EMBL:AAH71844.1 xref: EMBL:AAP35475.1 xref: EMBL:AAP97219.1 xref: EMBL:CAA09626.1 xref: UniProtKB:O95471 xref: UniProtKB:Q6IPN3 xref: UniProtKB:Q7Z4Y7 xref: UniProtKB:Q9BVN0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014672 ! CLDN7_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0014978 ! cldn7-pepp2 physical interaction [Term] id: CCO:B0049757 name: CNOT2_HUMAN def: "CCR4-NOT transcription complex subunit 2" [UniProtKB:Q9NZN8] synonym: "CCR4-associated factor 2" EXACT [UniProtKB:Q9NZN8] xref: EMBL:AAF29095.1 xref: EMBL:AAF29827.1 xref: EMBL:AAG39297.1 xref: EMBL:AAH02597.1 xref: EMBL:AAH11826.1 xref: EMBL:AAQ13426.1 xref: EMBL:BAA91313.1 xref: EMBL:CAB70869.1 xref: EMBL:CAE46054.1 xref: UniProtKB:Q9H3E0 xref: UniProtKB:Q9NSX5 xref: UniProtKB:Q9NWR6 xref: UniProtKB:Q9NZN8 xref: UniProtKB:Q9P028 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014676 ! CNOT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015054 ! cnot2-cnot3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000658 ! regulation of transcription from RNA polymerase II promoter, global relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0052344 ! CNOT2_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0064426 ! CNOT2_HUMAN-Phosphothreonine93 relationship: transforms_into CCO:B0064427 ! CNOT2_HUMAN-Phosphoserine165 [Term] id: CCO:B0049761 name: CA149_HUMAN def: "Uncharacterized protein C1orf149" [UniProtKB:Q9HAF1] synonym: "Sarcoma antigen NY-SAR-91" EXACT [UniProtKB:Q9HAF1] xref: EMBL:AAH16328.1 xref: EMBL:AAH56406.1 xref: EMBL:AAO65179.1 xref: EMBL:AAZ13760.1 xref: EMBL:BAB13898.1 xref: EMBL:CAD98071.1 xref: EMBL:CAE45838.1 xref: EMBL:CAI20549.1 xref: EMBL:CAI20550.1 xref: UniProtKB:Q4F967 xref: UniProtKB:Q7Z311 xref: UniProtKB:Q86WE3 xref: UniProtKB:Q9HAF1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014648 ! C1orf149_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: participates_in CCO:I0014956 ! c1orf149-l3mbtl2 physical interaction relationship: transforms_into CCO:B0052307 ! CA149_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0065807 ! CA149_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0065808 ! CA149_HUMAN-Phosphothreonine120 relationship: transforms_into CCO:B0065809 ! CA149_HUMAN-Phosphoserine122 [Term] id: CCO:B0049794 name: PPT1_HUMAN def: "Palmitoyl-protein thioesterase 1 precursor" [UniProtKB:P50897] synonym: "EC 3.1.2.22" EXACT [UniProtKB:P50897] synonym: "Palmitoyl-protein hydrolase 1" EXACT [UniProtKB:P50897] synonym: "PPT-1" EXACT [UniProtKB:P50897] xref: EMBL:AAA85337.1 xref: EMBL:AAB06236.1 xref: EMBL:AAB72224.1 xref: EMBL:AAH08426.1 xref: UniProtKB:P50897 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014938 ! PPT1_human relationship: has_function CCO:F0001935 ! palmitoyl-(protein) hydrolase activity relationship: has_function CCO:F0003106 ! palmitoyl-CoA hydrolase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0002802 ! positive regulation of receptor-mediated endocytosis relationship: participates_in CCO:P0002855 ! positive regulation of pinocytosis [Term] id: CCO:B0049806 name: OR8H1_HUMAN def: "Olfactory receptor 8H1" [UniProtKB:Q8NGG4] synonym: "Olfactory receptor OR11-180" EXACT [UniProtKB:Q8NGG4] xref: EMBL:BAC06055.1 xref: EMBL:DAA04735.1 xref: UniProtKB:Q6IFC5 xref: UniProtKB:Q8NGG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014893 ! OR8H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049809 name: A8MYY4_HUMAN def: "Putative uncharacterized protein OR8H3" [UniProtKB:A8MYY4] xref: UniProtKB:A8MYY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014895 ! OR8H3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049812 name: A8MYM5_HUMAN def: "Putative uncharacterized protein OR8H1" [UniProtKB:A8MYM5] xref: UniProtKB:A8MYM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014893 ! OR8H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049813 name: OR8B4_HUMAN def: "Olfactory receptor 8B4" [UniProtKB:Q96RC9] xref: EMBL:AAK94994.1 xref: EMBL:BAC06050.1 xref: UniProtKB:Q96RC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014887 ! OR8B4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049814 name: OR8H3_HUMAN def: "Olfactory receptor 8H3" [UniProtKB:Q8N146] synonym: "Olfactory receptor OR11-172" EXACT [UniProtKB:Q8N146] xref: EMBL:BAC05884.1 xref: EMBL:BAC06059.1 xref: EMBL:DAA04743.1 xref: UniProtKB:Q6IFB7 xref: UniProtKB:Q8N146 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014895 ! OR8H3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049816 name: OR8H2_HUMAN def: "Olfactory receptor 8H2" [UniProtKB:Q8N162] synonym: "Olfactory receptor OR11-171" EXACT [UniProtKB:Q8N162] xref: EMBL:BAC05883.1 xref: EMBL:BAC06063.1 xref: EMBL:DAA04739.1 xref: UniProtKB:Q6IFC1 xref: UniProtKB:Q8N162 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014894 ! OR8H2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049817 name: OR5MB_HUMAN def: "Olfactory receptor 5M11" [UniProtKB:Q96RB7] xref: EMBL:AAK95006.1 xref: UniProtKB:Q96RB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014884 ! OR5M11_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049841 name: SCND3_HUMAN def: "SCAN domain-containing protein 3" [UniProtKB:Q6R2W3] synonym: "Protein ZNF452" EXACT [UniProtKB:Q6R2W3] xref: EMBL:AAI10835.1 xref: EMBL:AAI11742.1 xref: EMBL:AAI11743.1 xref: EMBL:AAS01734.1 xref: EMBL:BAB67818.1 xref: EMBL:BAB71166.1 xref: EMBL:CAD28490.2 xref: EMBL:CAI17641.2 xref: UniProtKB:Q2NKL9 xref: UniProtKB:Q5SRJ3 xref: UniProtKB:Q6R2W3 xref: UniProtKB:Q8TCN2 xref: UniProtKB:Q96MV9 xref: UniProtKB:Q96PW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014999 ! SCAND3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049842 name: ZSC16_HUMAN def: "Zinc finger and SCAN domain-containing protein 16" [UniProtKB:Q9H4T2] synonym: "Zinc finger protein 392" EXACT [UniProtKB:Q9H4T2] synonym: "Zinc finger protein 435" EXACT [UniProtKB:Q9H4T2] xref: EMBL:AAH04255.1 xref: EMBL:BAB15257.1 xref: EMBL:CAC15900.2 xref: UniProtKB:Q9H4T2 xref: UniProtKB:Q9H6K2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015099 ! ZSCAN16_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014962 ! znf435-znf446 physical interaction relationship: participates_in CCO:I0020499 ! znf435-flj20551 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049848 name: RNF4_HUMAN def: "RING finger protein 4" [UniProtKB:P78317] xref: EMBL:AAC52022.1 xref: EMBL:AAH31935.1 xref: EMBL:BAA19122.1 xref: UniProtKB:P78317 xref: UniProtKB:Q49AR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014981 ! RNF4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052693 ! RNF4_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0052694 ! RNF4_HUMAN-Phosphoserine95 [Term] id: CCO:B0049885 name: Q59EB5_HUMAN def: "CSDA protein variant" [UniProtKB:Q59EB5] xref: EMBL:BAD93133.1 xref: UniProtKB:Q59EB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049887 name: Q2VIK8_HUMAN def: "RcNSEP1" [UniProtKB:Q2VIK8] xref: EMBL:ABB92460.1 xref: UniProtKB:Q2VIK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049888 name: Q59HE1_HUMAN def: "Germ cell specific Y-box binding protein variant" [UniProtKB:Q59HE1] xref: EMBL:BAD92055.1 xref: UniProtKB:Q59HE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049889 name: Q7KZ24_HUMAN def: "Nuclease sensitive element binding protein-1" [UniProtKB:Q7KZ24] xref: EMBL:AAA36569.1 xref: UniProtKB:Q7KZ24 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0049892 name: DBPA_HUMAN def: "DNA-binding protein A" [UniProtKB:P16989] synonym: "Cold shock domain-containing protein A" EXACT [UniProtKB:P16989] synonym: "Single-strand DNA-binding protein NF-GMB" EXACT [UniProtKB:P16989] xref: EMBL:AAA35749.1 xref: EMBL:AAA79243.1 xref: EMBL:AAH08801.1 xref: EMBL:AAH15564.1 xref: EMBL:AAH21926.1 xref: EMBL:CAA51261.1 xref: EMBL:CAA64631.1 xref: UniProtKB:P16989 xref: UniProtKB:Q14121 xref: UniProtKB:Q969N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014697 ! CSDA_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016849 ! map3k14-csda physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052353 ! DBPA_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0052354 ! DBPA_HUMAN-Phosphoserine134 [Term] id: CCO:B0049899 name: YBOX2_HUMAN def: "Y-box-binding protein 2" [UniProtKB:Q9Y2T7] synonym: "Contrin" EXACT [UniProtKB:Q9Y2T7] synonym: "Dbpc" EXACT [UniProtKB:Q9Y2T7] synonym: "DNA-binding protein C" EXACT [UniProtKB:Q9Y2T7] synonym: "Germ cell-specific Y-box-binding protein" EXACT [UniProtKB:Q9Y2T7] synonym: "MSY2 homolog" EXACT [UniProtKB:Q9Y2T7] xref: EMBL:AAD30662.1 xref: EMBL:AAH33800.1 xref: EMBL:AAH47760.1 xref: UniProtKB:Q8N4P0 xref: UniProtKB:Q9Y2T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015085 ! YBX2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000850 ! translational attenuation [Term] id: CCO:B0049905 name: Q24JP0_HUMAN def: "FAM13A1_v2 protein" [UniProtKB:Q24JP0] xref: EMBL:CAE18110.1 xref: UniProtKB:Q24JP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014728 ! FAM13A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0049915 name: RAMP3_HUMAN def: "Receptor activity-modifying protein 3 precursor" [UniProtKB:O60896] synonym: "Calcitonin-receptor-like receptor activity-modifying protein 3" EXACT [UniProtKB:O60896] synonym: "CRLR activity-modifying protein 3" EXACT [UniProtKB:O60896] xref: EMBL:AAH22304.1 xref: EMBL:AAP23300.1 xref: EMBL:CAA04474.1 xref: UniProtKB:O60896 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014972 ! RAMP3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0002530 ! coreceptor, soluble ligand activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020335 ! hspb3-ramp3 physical interaction relationship: participates_in CCO:I0020619 ! pdcd6ip-ramp3 physical interaction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0049929 name: SRBP1_HUMAN def: "Sterol regulatory element-binding protein 1" [UniProtKB:P36956] synonym: "SREBP-1" EXACT [UniProtKB:P36956] synonym: "Sterol regulatory element-binding transcription factor 1" EXACT [UniProtKB:P36956] xref: EMBL:AAB28522.2 xref: EMBL:AAB28523.1 xref: EMBL:AAC50051.2 xref: EMBL:AAH23621.1 xref: EMBL:AAH26962.1 xref: EMBL:AAH57388.1 xref: EMBL:AAH63281.1 xref: EMBL:BAD92846.1 xref: EMBL:EAW55689.1 xref: UniProtKB:P36956 xref: UniProtKB:Q16062 xref: UniProtKB:Q59F52 xref: UniProtKB:Q6P4R7 xref: UniProtKB:Q6PFW7 xref: UniProtKB:Q6PJ36 xref: UniProtKB:Q8TAK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015017 ! SREBF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005040 ! sterol response element binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0018982 ! atxn1-srebf1 physical interaction relationship: participates_in CCO:I0019061 ! atxn1-srebf1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0052786 ! SRBP1_HUMAN-Phosphotyrosine110 relationship: transforms_into CCO:B0052787 ! SRBP1_HUMAN-Phosphoserine1019 relationship: transforms_into CCO:B0052788 ! SRBP1_HUMAN-Phosphoserine1020 relationship: transforms_into CCO:B0070863 ! SRBP1_HUMAN-Phosphoserine117 [Term] id: CCO:B0049933 name: Q05BD5_HUMAN def: "SREBF2 protein" [UniProtKB:Q05BD5] xref: EMBL:AAH51385.1 xref: UniProtKB:Q05BD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015018 ! SREBF2_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0049934 name: SRBP2_HUMAN def: "Sterol regulatory element-binding protein 2" [UniProtKB:Q12772] synonym: "SREBP-2" EXACT [UniProtKB:Q12772] synonym: "Sterol regulatory element-binding transcription factor 2" EXACT [UniProtKB:Q12772] xref: EMBL:AAA50746.1 xref: EMBL:AAH51799.1 xref: EMBL:AAH56158.1 xref: EMBL:CAI22917.1 xref: EMBL:CAI41688.1 xref: EMBL:CAJ86452.1 xref: UniProtKB:Q12772 xref: UniProtKB:Q6GTH7 xref: UniProtKB:Q86V36 xref: UniProtKB:Q9UH04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015018 ! SREBF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008975 ! smad3-srebf2 physical interaction relationship: participates_in CCO:I0008976 ! smad3-srebf2-1 physical interaction relationship: participates_in CCO:I0008977 ! smad3-srebf2-2 physical interaction relationship: participates_in CCO:I0020417 ! rab11b-srebf2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: transforms_into CCO:B0052790 ! SRBP2_HUMAN-Phosphoserine1121 [Term] id: CCO:B0049991 name: SF3B1_HUMAN def: "Splicing factor 3B subunit 1" [UniProtKB:O75533] synonym: "Pre-mRNA-splicing factor SF3b 155 kDa subunit" EXACT [UniProtKB:O75533] synonym: "SAP 155" EXACT [UniProtKB:O75533] synonym: "SF3b155" EXACT [UniProtKB:O75533] synonym: "Spliceosome-associated protein 155" EXACT [UniProtKB:O75533] xref: EMBL:AAC28633.1 xref: EMBL:AAC97189.1 xref: UniProtKB:O75533 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015005 ! SF3B1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: transforms_into CCO:B0052733 ! SF3B1_HUMAN-Phosphothreonine142 relationship: transforms_into CCO:B0052734 ! SF3B1_HUMAN-Phosphothreonine207 relationship: transforms_into CCO:B0052735 ! SF3B1_HUMAN-Phosphothreonine211 relationship: transforms_into CCO:B0052736 ! SF3B1_HUMAN-Phosphothreonine223 relationship: transforms_into CCO:B0052737 ! SF3B1_HUMAN-Phosphothreonine227 relationship: transforms_into CCO:B0052738 ! SF3B1_HUMAN-Phosphothreonine235 relationship: transforms_into CCO:B0052739 ! SF3B1_HUMAN-Phosphothreonine244 relationship: transforms_into CCO:B0052740 ! SF3B1_HUMAN-Phosphothreonine248 relationship: transforms_into CCO:B0052741 ! SF3B1_HUMAN-Phosphothreonine257 relationship: transforms_into CCO:B0052742 ! SF3B1_HUMAN-Phosphothreonine261 relationship: transforms_into CCO:B0052743 ! SF3B1_HUMAN-Phosphothreonine267 relationship: transforms_into CCO:B0052744 ! SF3B1_HUMAN-Phosphothreonine296 relationship: transforms_into CCO:B0052745 ! SF3B1_HUMAN-Phosphothreonine299 relationship: transforms_into CCO:B0052746 ! SF3B1_HUMAN-Phosphothreonine313 relationship: transforms_into CCO:B0052747 ! SF3B1_HUMAN-Phosphothreonine316 relationship: transforms_into CCO:B0052748 ! SF3B1_HUMAN-Phosphothreonine326 relationship: transforms_into CCO:B0052749 ! SF3B1_HUMAN-Phosphothreonine328 relationship: transforms_into CCO:B0052750 ! SF3B1_HUMAN-Phosphoserine344 relationship: transforms_into CCO:B0052751 ! SF3B1_HUMAN-Phosphothreonine350 relationship: transforms_into CCO:B0052752 ! SF3B1_HUMAN-Phosphothreonine354 relationship: transforms_into CCO:B0052753 ! SF3B1_HUMAN-Phosphothreonine432 [Term] id: CCO:B0050004 name: PANK4_HUMAN def: "Pantothenate kinase 4" [UniProtKB:Q9NVE7] synonym: "EC 2.7.1.33" EXACT [UniProtKB:Q9NVE7] synonym: "hPanK4" EXACT [UniProtKB:Q9NVE7] synonym: "Pantothenic acid kinase 4" EXACT [UniProtKB:Q9NVE7] xref: EMBL:AAH43496.1 xref: EMBL:BAA91805.1 xref: EMBL:BAD97266.1 xref: EMBL:CAC09438.1 xref: EMBL:CAI20410.1 xref: EMBL:DAA00006.1 xref: UniProtKB:Q53EU3 xref: UniProtKB:Q5TA84 xref: UniProtKB:Q7RTX3 xref: UniProtKB:Q9H3X5 xref: UniProtKB:Q9NVE7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014907 ! PANK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000976 ! pantothenate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020617 ! pank4-pea15 physical interaction [Term] id: CCO:B0050006 name: CD72_HUMAN def: "B-cell differentiation antigen CD72" [UniProtKB:P21854] synonym: "CD72 antigen" EXACT [UniProtKB:P21854] synonym: "Lyb-2" EXACT [UniProtKB:P21854] xref: EMBL:AAA36189.1 xref: EMBL:AAH30227.1 xref: UniProtKB:P21854 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014654 ! CD72_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017842 ! cd5-cd72-1 physical interaction [Term] id: CCO:B0050075 name: CCHCR_HUMAN def: "Coiled-coil alpha-helical rod protein 1" [UniProtKB:Q8TD31] synonym: "Alpha-helical coiled-coil rod protein" EXACT [UniProtKB:Q8TD31] synonym: "Pg8" EXACT [UniProtKB:Q8TD31] synonym: "Putative gene 8 protein" EXACT [UniProtKB:Q8TD31] xref: EMBL:AAF74221.1 xref: EMBL:AAK55759.1 xref: EMBL:BAA81890.1 xref: EMBL:BAA82158.1 xref: EMBL:BAA91007.1 xref: EMBL:BAA91016.1 xref: EMBL:BAA91236.1 xref: EMBL:BAB63313.1 xref: EMBL:BAC54937.1 xref: UniProtKB:Q8TD31 xref: UniProtKB:Q9NRK8 xref: UniProtKB:Q9NWY9 xref: UniProtKB:Q9NXJ4 xref: UniProtKB:Q9NXK3 xref: UniProtKB:Q9Y6W1 xref: UniProtKB:Q9Y6W2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014652 ! CCHCR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019156 ! prkcg-cchcr1 physical interaction relationship: transforms_into CCO:B0052319 ! CCHCR_HUMAN-Phosphoserine88 [Term] id: CCO:B0050112 name: ZN566_HUMAN def: "Zinc finger protein 566" [UniProtKB:Q969W8] xref: EMBL:AAH07064.1 xref: EMBL:AAI04887.1 xref: EMBL:AAI04889.1 xref: EMBL:BAB55296.1 xref: UniProtKB:Q2M3J1 xref: UniProtKB:Q969W8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015092 ! ZNF566_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050113 name: ZN582_HUMAN def: "Zinc finger protein 582" [UniProtKB:Q96NG8] xref: EMBL:AAH11796.1 xref: EMBL:AAI01009.1 xref: EMBL:AAI01010.1 xref: EMBL:AAI01011.1 xref: EMBL:AAI01012.1 xref: EMBL:BAB70931.1 xref: UniProtKB:Q6PJT6 xref: UniProtKB:Q96NG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015093 ! ZNF582_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050166 name: IPO5_HUMAN def: "Importin-5" [UniProtKB:O00410] synonym: "Imp5" EXACT [UniProtKB:O00410] synonym: "Importin subunit beta-3" EXACT [UniProtKB:O00410] synonym: "Karyopherin beta-3" EXACT [UniProtKB:O00410] synonym: "Ran-binding protein 5" EXACT [UniProtKB:O00410] synonym: "RanBP5" EXACT [UniProtKB:O00410] xref: EMBL:AAC51317.1 xref: EMBL:AAH01497.1 xref: EMBL:AAH19309.1 xref: EMBL:CAA70103.1 xref: UniProtKB:O00410 xref: UniProtKB:O15257 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014777 ! IPO5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016586 ! tank-kpnb3 physical interaction relationship: transforms_into CCO:B0052450 ! IPO5_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0052451 ! IPO5_HUMAN-Phosphoserine827 [Term] id: CCO:B0050171 name: UBE2K_HUMAN def: "Ubiquitin-conjugating enzyme E2 K" [UniProtKB:P61086] synonym: "E2(25K)" EXACT [UniProtKB:P61086] synonym: "EC 6.3.2.19" EXACT [UniProtKB:P61086] synonym: "HIP-2" EXACT [UniProtKB:P61086] synonym: "Huntingtin-interacting protein 2" EXACT [UniProtKB:P61086] synonym: "Ubiquitin carrier protein" EXACT [UniProtKB:P61086] synonym: "Ubiquitin-conjugating enzyme E2-25 kDa" EXACT [UniProtKB:P61086] synonym: "Ubiquitin-protein ligase" EXACT [UniProtKB:P61086] xref: EMBL:AAC50633.1 xref: EMBL:AAH22804.1 xref: EMBL:AAH50600.1 xref: EMBL:BAA78555.1 xref: EMBL:BAA78556.1 xref: UniProtKB:A6NJC1 xref: UniProtKB:O54806 xref: UniProtKB:P27924 xref: UniProtKB:P61086 xref: UniProtKB:Q16721 xref: UniProtKB:Q9CVV9 xref: UniProtKB:Q9Y2D3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015075 ! UBE2K_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016053 ! hip2-pias4 physical interaction [Term] id: CCO:B0050187 name: Q8N882_HUMAN def: "cDNA FLJ39841 fis, clone SPLEN2014210, moderately similar to Rattus norvegicus alpha D integrin mRNA" [UniProtKB:Q8N882] xref: EMBL:BAC04967.1 xref: UniProtKB:Q8N882 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050188 name: Q4VAK1_HUMAN def: "Integrin, alpha M (Complement component 3 receptor 3 subunit)" [UniProtKB:Q4VAK1] xref: EMBL:AAH96347.1 xref: UniProtKB:Q4VAK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014788 ! ITGAM_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050189 name: ITAM_HUMAN def: "Integrin alpha-M precursor" [UniProtKB:P11215] synonym: "CD11 antigen-like family member B" EXACT [UniProtKB:P11215] synonym: "CD11b antigen" EXACT [UniProtKB:P11215] synonym: "Cell surface glycoprotein MAC-1 subunit alpha" EXACT [UniProtKB:P11215] synonym: "CR-3 alpha chain" EXACT [UniProtKB:P11215] synonym: "Leukocyte adhesion receptor MO1" EXACT [UniProtKB:P11215] synonym: "Neutrophil adherence receptor" EXACT [UniProtKB:P11215] xref: EMBL:AAA51960.1 xref: EMBL:AAA58410.1 xref: EMBL:AAA59491.1 xref: EMBL:AAA59544.1 xref: EMBL:AAA59903.1 xref: EMBL:AAB24821.1 xref: EMBL:AAH96348.1 xref: EMBL:AAH99660.1 xref: UniProtKB:P11215 xref: UniProtKB:Q4VAK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014788 ! ITGAM_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000251 ! glycoprotein binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050190 name: ITAD_HUMAN def: "Integrin alpha-D precursor" [UniProtKB:Q13349] synonym: "ADB2" EXACT [UniProtKB:Q13349] synonym: "CD11 antigen-like family member D" EXACT [UniProtKB:Q13349] synonym: "CD11d antigen" EXACT [UniProtKB:Q13349] synonym: "Leukointegrin alpha D" EXACT [UniProtKB:Q13349] xref: EMBL:AAB38547.1 xref: EMBL:AAB60634.1 xref: EMBL:AAB60635.1 xref: EMBL:AAB60636.1 xref: EMBL:AAB60637.1 xref: EMBL:AAB60638.1 xref: EMBL:AAF62875.1 xref: UniProtKB:Q13349 xref: UniProtKB:Q15575 xref: UniProtKB:Q15576 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014786 ! ITGAD_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050191 name: ITA11_HUMAN def: "Integrin alpha-11 precursor" [UniProtKB:Q9UKX5] xref: EMBL:AAD51919.2 xref: EMBL:AAF01258.1 xref: EMBL:AAL39001.1 xref: EMBL:CAB94392.1 xref: UniProtKB:Q8WYI8 xref: UniProtKB:Q9UKQ1 xref: UniProtKB:Q9UKX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014784 ! ITGA11_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050192 name: ITAX_HUMAN def: "Integrin alpha-X precursor" [UniProtKB:P20702] synonym: "CD11 antigen-like family member C" EXACT [UniProtKB:P20702] synonym: "CD11c antigen" EXACT [UniProtKB:P20702] synonym: "Leu M5" EXACT [UniProtKB:P20702] synonym: "Leukocyte adhesion glycoprotein p150,95 alpha chain" EXACT [UniProtKB:P20702] synonym: "Leukocyte adhesion receptor p150,95" EXACT [UniProtKB:P20702] xref: EMBL:AAA51620.1 xref: EMBL:AAA59180.1 xref: EMBL:AAH38237.1 xref: UniProtKB:P20702 xref: UniProtKB:Q8IVA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014789 ! ITGAX_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050193 name: Q59H14_HUMAN def: "PREDICTED: integrin, alpha D variant" [UniProtKB:Q59H14] xref: EMBL:BAD92182.1 xref: UniProtKB:Q59H14 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050195 name: Q8TES5_HUMAN def: "FLJ00114 protein" [UniProtKB:Q8TES5] synonym: "Putative uncharacterized protein ITGAX" EXACT [UniProtKB:Q8TES5] xref: EMBL:BAB84873.1 xref: UniProtKB:A8MZ95 xref: UniProtKB:Q8TES5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015244 ! FLJ00114_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050196 name: ITA2_HUMAN def: "Integrin alpha-2 precursor" [UniProtKB:P17301] synonym: "CD49 antigen-like family member B" EXACT [UniProtKB:P17301] synonym: "CD49b antigen" EXACT [UniProtKB:P17301] synonym: "Collagen receptor" EXACT [UniProtKB:P17301] synonym: "GPIa" EXACT [UniProtKB:P17301] synonym: "Platelet membrane glycoprotein Ia" EXACT [UniProtKB:P17301] synonym: "VLA-2 alpha chain" EXACT [UniProtKB:P17301] xref: EMBL:AAA16619.2 xref: EMBL:AAM34795.1 xref: EMBL:CAA34894.1 xref: UniProtKB:P17301 xref: UniProtKB:Q14595 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014785 ! ITGA2_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016291 ! itga2-itga2-1 physical interaction relationship: participates_in CCO:I0016296 ! itga2-itga2-2 physical interaction relationship: participates_in CCO:I0016302 ! itga2-itgb1-1 physical interaction relationship: participates_in CCO:I0016306 ! itgb1-itga2-1 physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0052502 ! ITA2_HUMAN-Phosphothreonine1177 [Term] id: CCO:B0050197 name: A8MPT3_HUMAN xref: UniProtKB:A8MPT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050198 name: A8MTX2_HUMAN def: "Putative uncharacterized protein ITGAE" [UniProtKB:A8MTX2] xref: UniProtKB:A8MTX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004904 ! ITGAE_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050199 name: Q96HB1_HUMAN def: "ITGAL protein" [UniProtKB:Q96HB1] synonym: "Integrin, alpha L (Antigen CD11A (P180), lymphocyte function-associated antigen 1; alpha polypeptide), isoform CRA_a" EXACT [UniProtKB:Q96HB1] xref: EMBL:AAH08777.1 xref: EMBL:EAW52243.1 xref: UniProtKB:Q96HB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014787 ! ITGAL_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050200 name: A8MZ95_HUMAN xref: UniProtKB:A8MZ95 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050202 name: ITAL_HUMAN def: "Integrin alpha-L precursor" [UniProtKB:P20701] synonym: "CD11 antigen-like family member A" EXACT [UniProtKB:P20701] synonym: "CD11a antigen" EXACT [UniProtKB:P20701] synonym: "Leukocyte adhesion glycoprotein LFA-1 alpha chain" EXACT [UniProtKB:P20701] synonym: "Leukocyte function-associated molecule 1 alpha chain" EXACT [UniProtKB:P20701] synonym: "LFA-1A" EXACT [UniProtKB:P20701] xref: EMBL:AAA16474.2 xref: EMBL:AAC31672.1 xref: EMBL:AAZ38713.1 xref: EMBL:CAA68747.1 xref: EMBL:CAA80461.1 xref: UniProtKB:O43746 xref: UniProtKB:P20701 xref: UniProtKB:Q45H73 xref: UniProtKB:Q9UBC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014787 ! ITGAL_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017816 ! icam3-itgal-1 direct interaction relationship: participates_in CCO:I0017954 ! icam1-itgal-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0050216 name: A7MBN2_HUMAN def: "TNC protein" [UniProtKB:A7MBN2] xref: EMBL:AAI51844.1 xref: UniProtKB:A7MBN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015032 ! TNC_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0050218 name: TENA_HUMAN def: "Tenascin precursor" [UniProtKB:P24821] synonym: "Cytotactin" EXACT [UniProtKB:P24821] synonym: "Glioma-associated-extracellular matrix antigen" EXACT [UniProtKB:P24821] synonym: "GMEM" EXACT [UniProtKB:P24821] synonym: "GP 150-225" EXACT [UniProtKB:P24821] synonym: "Hexabrachion" EXACT [UniProtKB:P24821] synonym: "JI" EXACT [UniProtKB:P24821] synonym: "Myotendinous antigen" EXACT [UniProtKB:P24821] synonym: "Neuronectin" EXACT [UniProtKB:P24821] synonym: "Tenascin-C" EXACT [UniProtKB:P24821] synonym: "TN" EXACT [UniProtKB:P24821] synonym: "TN-C" EXACT [UniProtKB:P24821] xref: EMBL:AAA52703.1 xref: EMBL:AAA88083.1 xref: EMBL:CAA39628.1 xref: EMBL:CAA55309.1 xref: UniProtKB:P24821 xref: UniProtKB:Q14583 xref: UniProtKB:Q15567 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015032 ! TNC_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0052828 ! TENA_HUMAN-Phosphoserine72 [Term] id: CCO:B0050221 name: ZN75A_HUMAN def: "Zinc finger protein 75A" [UniProtKB:Q96N20] xref: EMBL:AAI19653.1 xref: EMBL:AAI19654.1 xref: EMBL:BAB71092.1 xref: EMBL:CAA62935.1 xref: UniProtKB:Q0VDI8 xref: UniProtKB:Q92669 xref: UniProtKB:Q96N20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015096 ! ZNF75A_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050222 name: Q5JPG0_HUMAN xref: UniProtKB:Q5JPG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050223 name: A6NK62_HUMAN def: "Putative uncharacterized protein ZNF75D (Zinc finger protein 75) (D8C6)" [UniProtKB:A6NK62] xref: EMBL:CAQ08422.1 xref: UniProtKB:A6NK62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021037 ! ZNF75D_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050226 name: AAMP_HUMAN def: "Angio-associated migratory cell protein" [UniProtKB:Q13685] xref: EMBL:AAA68889.1 xref: EMBL:AAH08809.2 xref: EMBL:AAH20244.1 xref: EMBL:AAH39866.2 xref: EMBL:CAG33036.1 xref: UniProtKB:Q13685 xref: UniProtKB:Q8WUJ9 xref: UniProtKB:Q96H92 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014613 ! AAMP_human relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020677 ! th1l-aamp physical interaction [Term] id: CCO:B0050234 name: A7E2Y4_HUMAN def: "Cut-like homeobox 2" [UniProtKB:A7E2Y4] xref: EMBL:AAI51246.1 xref: UniProtKB:A7E2Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014694 ! CUX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0050242 name: MP2K5_HUMAN def: "Dual specificity mitogen-activated protein kinase kinase 5" [UniProtKB:Q13163] synonym: "EC 2.7.12.2" EXACT [UniProtKB:Q13163] synonym: "MAP kinase kinase 5" EXACT [UniProtKB:Q13163] synonym: "MAPK/ERK kinase 5" EXACT [UniProtKB:Q13163] synonym: "MAPKK 5" EXACT [UniProtKB:Q13163] xref: EMBL:AAA96146.1 xref: EMBL:AAB16851.1 xref: EMBL:AAB16852.2 xref: EMBL:AAH08838.1 xref: EMBL:AAP35426.1 xref: EMBL:CAG47025.1 xref: UniProtKB:Q13163 xref: UniProtKB:Q92961 xref: UniProtKB:Q92962 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014840 ! MAP2K5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017240 ! map3k3-map2k5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0052596 ! MP2K5_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0052597 ! MP2K5_HUMAN-Phosphothreonine315 [Term] id: CCO:B0050254 name: SFRS3_HUMAN def: "Splicing factor, arginine/serine-rich 3" [UniProtKB:P84103] synonym: "Pre-mRNA-splicing factor SRP20" EXACT [UniProtKB:P84103] xref: EMBL:AAA36648.1 xref: EMBL:AAD44523.1 xref: EMBL:AAH00914.1 xref: EMBL:AAH69018.1 xref: EMBL:AAP35663.1 xref: EMBL:CAI19115.1 xref: UniProtKB:O08831 xref: UniProtKB:P23152 xref: UniProtKB:P84103 xref: UniProtKB:Q5R3K0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015006 ! SFRS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: transforms_into CCO:B0052754 ! SFRS3_HUMAN-Phosphoserine81 relationship: transforms_into CCO:B0052755 ! SFRS3_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0052756 ! SFRS3_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0052757 ! SFRS3_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0052758 ! SFRS3_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0052759 ! SFRS3_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0052760 ! SFRS3_HUMAN-Phosphoserine150 relationship: transforms_into CCO:B0052761 ! SFRS3_HUMAN-Phosphoserine152 [Term] id: CCO:B0050270 name: Q75MM1_HUMAN def: "WUGSC:H_NH0244E06.1 protein" [UniProtKB:Q75MM1] xref: EMBL:AAF19244.1 xref: UniProtKB:Q75MM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015215 ! WUGSC:H_NH0244E06.1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050272 name: Q7Z684_HUMAN def: "Putative uncharacterized protein DKFZp779G118" [UniProtKB:Q7Z684] xref: EMBL:CAD97768.1 xref: UniProtKB:Q7Z684 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015227 ! DKFZp779G118_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050274 name: Q5T7C4_HUMAN def: "High-mobility group box 1" [UniProtKB:Q5T7C4] xref: EMBL:CAI15603.1 xref: UniProtKB:Q5T7C4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004812 ! HMGB1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050275 name: HMG4L_HUMAN def: "High mobility group protein B3-like" [UniProtKB:Q3SYE8] synonym: "High-mobility group protein 4-like" EXACT [UniProtKB:Q3SYE8] xref: EMBL:AAI03850.1 xref: EMBL:AAI03851.1 xref: EMBL:AAI03852.1 xref: UniProtKB:Q3SYE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014765 ! HMG4L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050276 name: HMGLX_HUMAN def: "High mobility group protein 1-like 10" [UniProtKB:Q9UGV6] synonym: "HMG-1L10" EXACT [UniProtKB:Q9UGV6] xref: UniProtKB:Q9UGV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014764 ! HMG1L10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001133 ! negative regulation of transcriptional preinitiation complex assembly [Term] id: CCO:B0050277 name: HMGB4_HUMAN def: "High mobility group protein B4" [UniProtKB:Q8WW32] xref: EMBL:AAH21180.1 xref: UniProtKB:Q8WW32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014768 ! HMGB4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050279 name: HMGB3_HUMAN def: "High mobility group protein B3" [UniProtKB:O15347] synonym: "High mobility group protein 2a" EXACT [UniProtKB:O15347] synonym: "High mobility group protein 4" EXACT [UniProtKB:O15347] synonym: "HMG-2a" EXACT [UniProtKB:O15347] synonym: "HMG-4" EXACT [UniProtKB:O15347] xref: EMBL:AAH70482.1 xref: EMBL:CAA71143.1 xref: UniProtKB:O15347 xref: UniProtKB:O95556 xref: UniProtKB:Q6NS40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014767 ! HMGB3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002392 ! negative regulation of B cell differentiation relationship: participates_in CCO:P0002452 ! negative regulation of myeloid cell differentiation [Term] id: CCO:B0050283 name: Q16466_HUMAN def: "Non-histone chromosomal protein" [UniProtKB:Q16466] xref: EMBL:AAC15850.1 xref: UniProtKB:Q16466 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050286 name: HG3BL_HUMAN def: "Putative high mobility group protein B3-like protein" [UniProtKB:P0C6E5] xref: UniProtKB:P0C6E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050288 name: Q6NSH1_HUMAN def: "High-mobility group box 4" [UniProtKB:Q6NSH1] xref: EMBL:AAH70148.1 xref: UniProtKB:Q6NSH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014768 ! HMGB4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050289 name: Q5T7C6_HUMAN def: "High-mobility group box 1" [UniProtKB:Q5T7C6] xref: EMBL:CAI15601.1 xref: UniProtKB:Q5T7C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004812 ! HMGB1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050294 name: HMGB2_HUMAN def: "High mobility group protein B2" [UniProtKB:P26583] synonym: "High mobility group protein 2" EXACT [UniProtKB:P26583] synonym: "HMG-2" EXACT [UniProtKB:P26583] xref: EMBL:AAA58659.1 xref: EMBL:AAH01063.1 xref: EMBL:AAI00020.1 xref: EMBL:AAV38585.1 xref: EMBL:CAA44395.1 xref: EMBL:CAA78938.1 xref: UniProtKB:P26583 xref: UniProtKB:Q5U072 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014766 ! HMGB2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0052421 ! HMGB2_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0052422 ! HMGB2_HUMAN-Phosphotyrosine155 relationship: transforms_into CCO:B0052423 ! HMGB2_HUMAN-Phosphotyrosine162 [Term] id: CCO:B0050299 name: Q5T7C0_HUMAN def: "High-mobility group box 1" [UniProtKB:Q5T7C0] xref: EMBL:CAI15606.1 xref: UniProtKB:Q5T7C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004812 ! HMGB1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050340 name: CD40L_HUMAN def: "CD40 ligand" [UniProtKB:P29965] synonym: "CD154 antigen" EXACT [UniProtKB:P29965] synonym: "CD40-L" EXACT [UniProtKB:P29965] synonym: "T-cell antigen Gp39" EXACT [UniProtKB:P29965] synonym: "TNF-related activation protein" EXACT [UniProtKB:P29965] synonym: "TRAP" EXACT [UniProtKB:P29965] synonym: "Tumor necrosis factor ligand superfamily member 5" EXACT [UniProtKB:P29965] xref: EMBL:AAA35662.1 xref: EMBL:AAH71754.1 xref: EMBL:AAH74950.1 xref: EMBL:BAA06599.1 xref: EMBL:CAA48077.1 xref: EMBL:CAA48554.1 xref: EMBL:CAA78737.1 xref: UniProtKB:P29965 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014653 ! CD40LG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002040 ! B cell proliferation relationship: transforms_into CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 [Term] id: CCO:B0050345 name: FOXO3_HUMAN def: "Forkhead box protein O3" [UniProtKB:O43524] synonym: "AF6q21 protein" EXACT [UniProtKB:O43524] synonym: "Forkhead in rhabdomyosarcoma-like 1" EXACT [UniProtKB:O43524] xref: EMBL:AAC39592.1 xref: EMBL:AAH20227.1 xref: EMBL:AAH21224.1 xref: EMBL:AAH68552.1 xref: EMBL:CAA04860.1 xref: EMBL:CAA04861.1 xref: EMBL:CAI16295.1 xref: EMBL:CAI16405.1 xref: UniProtKB:O15171 xref: UniProtKB:O43524 xref: UniProtKB:Q5T2I7 xref: UniProtKB:Q9BZ04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014732 ! FOXO3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002462 ! positive regulation of erythrocyte differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0052389 ! FOXO3_HUMAN-Phosphothreonine32 relationship: transforms_into CCO:B0052390 ! FOXO3_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0052391 ! FOXO3_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0052392 ! FOXO3_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0052393 ! FOXO3_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0052394 ! FOXO3_HUMAN-Phosphothreonine427 [Term] id: CCO:B0050346 name: Q9UPC2_HUMAN def: "Fork head-like protein" [UniProtKB:Q9UPC2] xref: EMBL:AAD02923.1 xref: UniProtKB:Q9UPC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015264 ! FKHRL1P2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050348 name: AHRR_HUMAN def: "Aryl hydrocarbon receptor repressor" [UniProtKB:A9YTQ3] synonym: "AhR repressor" EXACT [UniProtKB:A9YTQ3] synonym: "AhRR" EXACT [UniProtKB:A9YTQ3] xref: EMBL:AAG33381.1 xref: EMBL:AAI51853.1 xref: EMBL:AAI52407.1 xref: EMBL:ABX89616.1 xref: EMBL:BAA86548.1 xref: EMBL:EAW50992.1 xref: UniProtKB:A7MBN5 xref: UniProtKB:A9YTQ3 xref: UniProtKB:Q9HAZ3 xref: UniProtKB:Q9ULI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014622 ! AHRR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0050358 name: MLL3_HUMAN def: "Histone-lysine N-methyltransferase MLL3" [UniProtKB:Q8NEZ4] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q8NEZ4] synonym: "Homologous to ALR protein" EXACT [UniProtKB:Q8NEZ4] synonym: "Lysine N-methyltransferase 2C" EXACT [UniProtKB:Q8NEZ4] synonym: "Myeloid/lymphoid or mixed-lineage leukemia protein 3" EXACT [UniProtKB:Q8NEZ4] xref: EMBL:AAD45822.1 xref: EMBL:AAF74766.2 xref: EMBL:AAK00583.1 xref: EMBL:BAA96030.2 xref: EMBL:BAB14179.1 xref: EMBL:BAC11409.1 xref: EMBL:CAD38780.1 xref: UniProtKB:Q8NC02 xref: UniProtKB:Q8NDF6 xref: UniProtKB:Q8NEZ4 xref: UniProtKB:Q9H9P4 xref: UniProtKB:Q9NR13 xref: UniProtKB:Q9P222 xref: UniProtKB:Q9UDR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014832 ! MLL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0052582 ! MLL3_HUMAN-N6-acetyllysine2809 relationship: transforms_into CCO:B0052583 ! MLL3_HUMAN-Phosphotyrosine4018 relationship: transforms_into CCO:B0052584 ! MLL3_HUMAN-Phosphoserine4022 relationship: transforms_into CCO:B0052585 ! MLL3_HUMAN-Phosphoserine4034 relationship: transforms_into CCO:B0052586 ! MLL3_HUMAN-Phosphoserine4050 [Term] id: CCO:B0050359 name: MLL2_HUMAN def: "Histone-lysine N-methyltransferase MLL2" [UniProtKB:O14686] synonym: "ALL1-related protein" EXACT [UniProtKB:O14686] synonym: "EC 2.1.1.43" EXACT [UniProtKB:O14686] synonym: "Lysine N-methyltransferase 2B" EXACT [UniProtKB:O14686] synonym: "Myeloid/lymphoid or mixed-lineage leukemia protein 2" EXACT [UniProtKB:O14686] xref: EMBL:AAC51734.1 xref: EMBL:AAC51735.1 xref: UniProtKB:O14686 xref: UniProtKB:O14687 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014831 ! MLL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001616 ! histone methyltransferase complex relationship: participates_in CCO:I0016336 ! mll2-rbq3-1 physical interaction relationship: participates_in CCO:I0017944 ! mll2-ash2l physical interaction relationship: participates_in CCO:I0017945 ! mll2-rbq3-3 physical interaction relationship: participates_in CCO:I0017946 ! mll2-ash2l-1 physical interaction relationship: participates_in CCO:I0018107 ! esr1-mll2 direct interaction relationship: participates_in CCO:I0018244 ! mll2-rbq3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052579 ! MLL2_HUMAN-Phosphoserine1545 relationship: transforms_into CCO:B0052580 ! MLL2_HUMAN-Phosphoserine2855 relationship: transforms_into CCO:B0052581 ! MLL2_HUMAN-Phosphoserine4463 [Term] id: CCO:B0050490 name: NLE1_HUMAN def: "Notchless protein homolog 1" [UniProtKB:Q9NVX2] xref: EMBL:AAH02884.2 xref: EMBL:AAH12075.1 xref: EMBL:BAA91621.1 xref: EMBL:CAA06444.1 xref: UniProtKB:O60868 xref: UniProtKB:Q9BU54 xref: UniProtKB:Q9NVX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014852 ! NLE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015078 ! ewsr1-nle1 physical interaction relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: transforms_into CCO:B0052610 ! NLE1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0052611 ! NLE1_HUMAN-Phosphoserine79 [Term] id: CCO:B0050497 name: PLEC1_HUMAN def: "Plectin-1" [UniProtKB:Q15149] synonym: "HD1" EXACT [UniProtKB:Q15149] synonym: "Hemidesmosomal protein 1" EXACT [UniProtKB:Q15149] synonym: "PCN" EXACT [UniProtKB:Q15149] synonym: "Plectin-11" EXACT [UniProtKB:Q15149] synonym: "Plectin-6" EXACT [UniProtKB:Q15149] synonym: "PLTN" EXACT [UniProtKB:Q15149] xref: EMBL:AAB05427.1 xref: EMBL:AAB05428.1 xref: EMBL:AAR95680.1 xref: EMBL:AAR95684.1 xref: EMBL:CAA65765.1 xref: EMBL:CAA91196.1 xref: UniProtKB:Q15148 xref: UniProtKB:Q15149 xref: UniProtKB:Q16640 xref: UniProtKB:Q6S376 xref: UniProtKB:Q6S380 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014929 ! PLEC1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0052634 ! PLEC1_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0052635 ! PLEC1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0052636 ! PLEC1_HUMAN-Phosphoserine720 relationship: transforms_into CCO:B0052637 ! PLEC1_HUMAN-Phosphoserine782 relationship: transforms_into CCO:B0052638 ! PLEC1_HUMAN-Phosphoserine1435 relationship: transforms_into CCO:B0052639 ! PLEC1_HUMAN-Phosphoserine1644 relationship: transforms_into CCO:B0052640 ! PLEC1_HUMAN-Phosphoserine1721 relationship: transforms_into CCO:B0052641 ! PLEC1_HUMAN-Phosphoserine2755 relationship: transforms_into CCO:B0052642 ! PLEC1_HUMAN-Phosphothreonine2814 relationship: transforms_into CCO:B0052643 ! PLEC1_HUMAN-Phosphotyrosine3033 relationship: transforms_into CCO:B0052644 ! PLEC1_HUMAN-Phosphotyrosine3362 relationship: transforms_into CCO:B0052645 ! PLEC1_HUMAN-Phosphothreonine4030 relationship: transforms_into CCO:B0052646 ! PLEC1_HUMAN-Phosphoserine4382 relationship: transforms_into CCO:B0052647 ! PLEC1_HUMAN-Phosphoserine4384 relationship: transforms_into CCO:B0052648 ! PLEC1_HUMAN-Phosphoserine4385 relationship: transforms_into CCO:B0052649 ! PLEC1_HUMAN-Phosphoserine4386 relationship: transforms_into CCO:B0052650 ! PLEC1_HUMAN-Phosphoserine4389 relationship: transforms_into CCO:B0052651 ! PLEC1_HUMAN-Phosphoserine4390 relationship: transforms_into CCO:B0052652 ! PLEC1_HUMAN-Phosphoserine4391 relationship: transforms_into CCO:B0052653 ! PLEC1_HUMAN-Phosphoserine4396 relationship: transforms_into CCO:B0052654 ! PLEC1_HUMAN-Phosphothreonine4402 relationship: transforms_into CCO:B0052655 ! PLEC1_HUMAN-Phosphothreonine4411 relationship: transforms_into CCO:B0052656 ! PLEC1_HUMAN-Phosphothreonine4539 relationship: transforms_into CCO:B0052657 ! PLEC1_HUMAN-Phosphotyrosine4611 relationship: transforms_into CCO:B0052658 ! PLEC1_HUMAN-Phosphoserine4613 relationship: transforms_into CCO:B0052659 ! PLEC1_HUMAN-Phosphotyrosine4615 relationship: transforms_into CCO:B0052660 ! PLEC1_HUMAN-Phosphoserine4620 relationship: transforms_into CCO:B0052661 ! PLEC1_HUMAN-Phosphoserine4622 relationship: transforms_into CCO:B0052662 ! PLEC1_HUMAN-Phosphothreonine4623 relationship: transforms_into CCO:B0052663 ! PLEC1_HUMAN-Phosphoserine4626 relationship: transforms_into CCO:B0069405 ! PLEC1_HUMAN-Phosphoserine1732 relationship: transforms_into CCO:B0069406 ! PLEC1_HUMAN-Phosphotyrosine4155 relationship: transforms_into CCO:B0069407 ! PLEC1_HUMAN-Phosphoserine4392 relationship: transforms_into CCO:B0069408 ! PLEC1_HUMAN-Phosphotyrosine4393 relationship: transforms_into CCO:B0069409 ! PLEC1_HUMAN-Phosphothreonine4628 relationship: transforms_into CCO:B0069410 ! PLEC1_HUMAN-Phosphoserine4642 relationship: transforms_into CCO:B0069411 ! PLEC1_HUMAN-Phosphoserine4658 [Term] id: CCO:B0050501 name: EPIPL_HUMAN def: "Epiplakin" [UniProtKB:P58107] synonym: "450 kDa epidermal antigen" EXACT [UniProtKB:P58107] xref: EMBL:BAB40803.1 xref: EMBL:BAC92750.1 xref: UniProtKB:P58107 xref: UniProtKB:Q76E58 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014716 ! EPPK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016507 ! ikbkg-eppk1 physical interaction relationship: participates_in CCO:I0016603 ! map3k1-eppk1 physical interaction relationship: participates_in CCO:I0016686 ! map3k3-eppk1 physical interaction relationship: participates_in CCO:I0016995 ! tnfrsf1a-eppk1 physical interaction relationship: transforms_into CCO:B0052375 ! EPIPL_HUMAN-Phosphoserine2691 relationship: transforms_into CCO:B0052376 ! EPIPL_HUMAN-Phosphoserine4619 relationship: transforms_into CCO:B0052377 ! EPIPL_HUMAN-Phosphoserine4827 relationship: transforms_into CCO:B0052378 ! EPIPL_HUMAN-Phosphoserine4829 relationship: transforms_into CCO:B0052379 ! EPIPL_HUMAN-Phosphothreonine4833 [Term] id: CCO:B0050510 name: IF4B_HUMAN def: "Eukaryotic translation initiation factor 4B" [UniProtKB:P23588] synonym: "eIF-4B" EXACT [UniProtKB:P23588] xref: EMBL:AAH73139.1 xref: EMBL:AAH73154.1 xref: EMBL:AAH98437.1 xref: EMBL:BAB82380.1 xref: EMBL:BAD96248.1 xref: EMBL:CAA39265.1 xref: EMBL:CAG33239.1 xref: EMBL:EAW96657.1 xref: UniProtKB:P23588 xref: UniProtKB:Q4G0E3 xref: UniProtKB:Q53HQ2 xref: UniProtKB:Q6GPH5 xref: UniProtKB:Q6IB46 xref: UniProtKB:Q8WYK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014773 ! EIF4B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0017636 ! eif4b-npm_alk physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0052431 ! IF4B_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0052432 ! IF4B_HUMAN-Phosphoserine192 relationship: transforms_into CCO:B0052433 ! IF4B_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0052434 ! IF4B_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0052435 ! IF4B_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0052436 ! IF4B_HUMAN-Phosphoserine445 relationship: transforms_into CCO:B0052437 ! IF4B_HUMAN-Phosphoserine459 relationship: transforms_into CCO:B0052438 ! IF4B_HUMAN-Phosphothreonine461 relationship: transforms_into CCO:B0052439 ! IF4B_HUMAN-Phosphoserine495 relationship: transforms_into CCO:B0052440 ! IF4B_HUMAN-Phosphoserine498 relationship: transforms_into CCO:B0052441 ! IF4B_HUMAN-Phosphoserine504 relationship: transforms_into CCO:B0052442 ! IF4B_HUMAN-Phosphoserine597 relationship: transforms_into CCO:B0067025 ! IF4B_HUMAN-Phosphoserine497 [Term] id: CCO:B0050528 name: CNOT7_HUMAN def: "CCR4-NOT transcription complex subunit 7" [UniProtKB:Q9UIV1] synonym: "BTG1-binding factor 1" EXACT [UniProtKB:Q9UIV1] synonym: "CAF-1" EXACT [UniProtKB:Q9UIV1] synonym: "CCR4-associated factor 1" EXACT [UniProtKB:Q9UIV1] xref: EMBL:AAF01500.1 xref: EMBL:AAH60852.1 xref: EMBL:AAH70187.1 xref: EMBL:AAP97145.1 xref: EMBL:EAW63820.1 xref: UniProtKB:A8MZM5 xref: UniProtKB:Q7Z530 xref: UniProtKB:Q9UIV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014677 ! CNOT7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000930 ! CCR4-NOT complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0050534 name: CNOT8_HUMAN def: "CCR4-NOT transcription complex subunit 8" [UniProtKB:Q9UFF9] synonym: "CAF1-like protein" EXACT [UniProtKB:Q9UFF9] synonym: "CAF2" EXACT [UniProtKB:Q9UFF9] synonym: "CALIFp" EXACT [UniProtKB:Q9UFF9] synonym: "CCR4-associated factor 8" EXACT [UniProtKB:Q9UFF9] xref: EMBL:AAD02685.1 xref: EMBL:AAF29830.1 xref: EMBL:AAH17366.1 xref: EMBL:AAP35503.1 xref: EMBL:AAP97157.1 xref: EMBL:BAB15119.1 xref: EMBL:CAB59181.1 xref: UniProtKB:O95709 xref: UniProtKB:Q7Z521 xref: UniProtKB:Q9H6Y1 xref: UniProtKB:Q9UFF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014678 ! CNOT8_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015035 ! btg1-cnot8 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0050546 name: TF3B_HUMAN def: "Transcription factor IIIB 90 kDa subunit" [UniProtKB:Q92994] synonym: "B-related factor 1" EXACT [UniProtKB:Q92994] synonym: "BRF-1" EXACT [UniProtKB:Q92994] synonym: "hBRF" EXACT [UniProtKB:Q92994] synonym: "hTFIIIB90" EXACT [UniProtKB:Q92994] synonym: "TAF3B2" EXACT [UniProtKB:Q92994] synonym: "TATA box-binding protein-associated factor, RNA polymerase III, subunit 2" EXACT [UniProtKB:Q92994] synonym: "TFIIIB90" EXACT [UniProtKB:Q92994] xref: EMBL:AAB38876.1 xref: EMBL:AAC50170.1 xref: EMBL:AAH71637.1 xref: EMBL:AAH86856.1 xref: EMBL:CAC04512.1 xref: EMBL:CAC04513.1 xref: EMBL:CAC04514.1 xref: UniProtKB:Q13223 xref: UniProtKB:Q5PR24 xref: UniProtKB:Q6IQ02 xref: UniProtKB:Q92994 xref: UniProtKB:Q9HCW6 xref: UniProtKB:Q9HCW7 xref: UniProtKB:Q9HCW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015034 ! BRF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017424 ! dtnbp1-brf1 physical interaction relationship: participates_in CCO:I0019170 ! tbp-brf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0052829 ! TF3B_HUMAN-Phosphoserine433 relationship: transforms_into CCO:B0052830 ! TF3B_HUMAN-Phosphoserine553 relationship: transforms_into CCO:B0071363 ! TF3B_HUMAN-Phosphothreonine365 relationship: transforms_into CCO:B0071364 ! TF3B_HUMAN-Phosphoserine450 [Term] id: CCO:B0050549 name: Q96KX3_HUMAN def: "BRF1 protein" [UniProtKB:Q96KX3] synonym: "BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), isoform CRA_c" EXACT [UniProtKB:Q96KX3] xref: EMBL:AAH16743.1 xref: EMBL:EAW81908.1 xref: UniProtKB:Q96KX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015034 ! BRF1_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0050581 name: IPO8_HUMAN def: "Importin-8" [UniProtKB:O15397] synonym: "Imp8" EXACT [UniProtKB:O15397] synonym: "Ran-binding protein 8" EXACT [UniProtKB:O15397] synonym: "RanBP8" EXACT [UniProtKB:O15397] xref: EMBL:AAB67052.1 xref: UniProtKB:O15397 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014778 ! IPO8_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001985 ! Ran GTPase binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016991 ! tnfrsf1a-ipo8 physical interaction relationship: participates_in CCO:I0017038 ! tnfrsf1b-ipo8 physical interaction relationship: participates_in CCO:I0017063 ! tradd-ipo8 physical interaction relationship: participates_in CCO:I0018975 ! atxn1-ipo8 physical interaction relationship: participates_in CCO:I0019078 ! atxn1-ipo8-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0050587 name: ARS2_HUMAN def: "Arsenite-resistance protein 2" [UniProtKB:Q9BXP5] xref: EMBL:AAD17774.1 xref: EMBL:AAH00082.2 xref: EMBL:AAI09118.1 xref: EMBL:AAK21005.1 xref: EMBL:AAK21006.1 xref: EMBL:CAB46374.2 xref: EMBL:EAL23815.1 xref: EMBL:EAW76467.1 xref: UniProtKB:A4D2E5 xref: UniProtKB:A6NK22 xref: UniProtKB:O95808 xref: UniProtKB:Q32MI4 xref: UniProtKB:Q9BWP6 xref: UniProtKB:Q9BXP4 xref: UniProtKB:Q9BXP5 xref: UniProtKB:Q9Y4S4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014635 ! ARS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019657 ! ars2-chd3 physical interaction relationship: participates_in CCO:I0019658 ! ars2-git1 physical interaction relationship: transforms_into CCO:B0052290 ! ARS2_HUMAN-Phosphotyrosine8 relationship: transforms_into CCO:B0052291 ! ARS2_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0052292 ! ARS2_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0052293 ! ARS2_HUMAN-Phosphoserine493 relationship: transforms_into CCO:B0052294 ! ARS2_HUMAN-Phosphoserine540 relationship: transforms_into CCO:B0052295 ! ARS2_HUMAN-Phosphothreonine544 relationship: transforms_into CCO:B0052296 ! ARS2_HUMAN-Phosphotyrosine624 relationship: transforms_into CCO:B0052297 ! ARS2_HUMAN-Phosphotyrosine625 relationship: transforms_into CCO:B0065753 ! ARS2_HUMAN-Phosphoserine136 [Term] id: CCO:B0050612 name: NCKP1_HUMAN def: "Nck-associated protein 1" [UniProtKB:Q9Y2A7] synonym: "Membrane-associated protein HEM-2" EXACT [UniProtKB:Q9Y2A7] synonym: "NAP 1" EXACT [UniProtKB:Q9Y2A7] synonym: "p125Nap1" EXACT [UniProtKB:Q9Y2A7] xref: EMBL:AAH15025.1 xref: EMBL:BAA25513.2 xref: EMBL:BAA77295.1 xref: UniProtKB:O60329 xref: UniProtKB:Q9Y2A7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014845 ! NCKAP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0018143 ! abi1-nckap1-3 physical interaction relationship: participates_in CCO:I0019343 ! abi1-nckap1-2 physical interaction [Term] id: CCO:B0050621 name: WDR1_HUMAN def: "WD repeat-containing protein 1" [UniProtKB:O75083] synonym: "Actin-interacting protein 1" EXACT [UniProtKB:O75083] synonym: "AIP1" EXACT [UniProtKB:O75083] synonym: "NORI-1" EXACT [UniProtKB:O75083] xref: EMBL:AAD05044.1 xref: EMBL:AAD05045.1 xref: EMBL:AAH00201.1 xref: EMBL:AAH02489.1 xref: EMBL:AAH30541.1 xref: EMBL:BAA31855.2 xref: EMBL:CAB43276.1 xref: EMBL:CAB53674.2 xref: UniProtKB:O75083 xref: UniProtKB:O75313 xref: UniProtKB:Q8N6E5 xref: UniProtKB:Q9UG05 xref: UniProtKB:Q9UG78 xref: UniProtKB:Q9UQE0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015081 ! WDR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0052892 ! WDR1_HUMAN-Phosphotyrosine238 [Term] id: CCO:B0050679 name: ARI5B_HUMAN def: "AT-rich interactive domain-containing protein 5B" [UniProtKB:Q14865] synonym: "ARID domain-containing protein 5B" EXACT [UniProtKB:Q14865] synonym: "Modulator recognition factor 2" EXACT [UniProtKB:Q14865] synonym: "MRF-2" EXACT [UniProtKB:Q14865] synonym: "Mrf1-like" EXACT [UniProtKB:Q14865] xref: EMBL:AAA59870.1 xref: EMBL:AAH36831.1 xref: EMBL:BAB15012.1 xref: EMBL:CAD97814.1 xref: EMBL:CAE46013.1 xref: EMBL:CAH72685.1 xref: EMBL:CAH72686.1 xref: UniProtKB:Q14865 xref: UniProtKB:Q5VST4 xref: UniProtKB:Q7Z3M4 xref: UniProtKB:Q8N421 xref: UniProtKB:Q9H786 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014633 ! ARID5B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052286 ! ARI5B_HUMAN-Phosphoserine1002 [Term] id: CCO:B0050696 name: IDHC_HUMAN def: "Isocitrate dehydrogenase [NADP] cytoplasmic" [UniProtKB:O75874] synonym: "Cytosolic NADP-isocitrate dehydrogenase" EXACT [UniProtKB:O75874] synonym: "EC 1.1.1.42" EXACT [UniProtKB:O75874] synonym: "IDH" EXACT [UniProtKB:O75874] synonym: "IDP" EXACT [UniProtKB:O75874] synonym: "NADP(+)-specific ICDH" EXACT [UniProtKB:O75874] synonym: "Oxalosuccinate decarboxylase" EXACT [UniProtKB:O75874] xref: EMBL:AAB17375.1 xref: EMBL:AAD02918.1 xref: EMBL:AAD29284.1 xref: EMBL:AAH12846.1 xref: EMBL:CAB66637.1 xref: UniProtKB:O75874 xref: UniProtKB:Q93090 xref: UniProtKB:Q9NTJ9 xref: UniProtKB:Q9UKW8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014771 ! IDH1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000850 ! isocitrate dehydrogenase (NADP+) activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0020038 ! idh1-zhx1 physical interaction [Term] id: CCO:B0050722 name: GCH1_HUMAN def: "GTP cyclohydrolase 1" [UniProtKB:P30793] synonym: "EC 3.5.4.16" EXACT [UniProtKB:P30793] synonym: "GTP cyclohydrolase I" EXACT [UniProtKB:P30793] synonym: "GTP-CH-I" EXACT [UniProtKB:P30793] xref: EMBL:AAB16861.1 xref: EMBL:AAB23164.1 xref: EMBL:AAB23165.1 xref: EMBL:AAB23166.1 xref: EMBL:AAB42186.1 xref: EMBL:AAB60633.1 xref: EMBL:AAD38866.1 xref: EMBL:AAD38868.1 xref: EMBL:AAH25415.1 xref: EMBL:CAA78908.1 xref: EMBL:CAA83213.1 xref: EMBL:CAB77391.1 xref: EMBL:CAB77392.1 xref: UniProtKB:P30793 xref: UniProtKB:Q9Y4I8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014741 ! GCH1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000429 ! GTP cyclohydrolase I activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016191 ! gch1-aha1-2 physical interaction relationship: participates_in CCO:I0018231 ! gch1-aha1-1 physical interaction relationship: participates_in CCO:I0018232 ! gch1-cb1_1p1-1 physical interaction relationship: participates_in CCO:I0018233 ! gch1-hsc70-1 physical interaction relationship: participates_in CCO:I0018234 ! gch1-rab26-1 physical interaction relationship: participates_in CCO:I0018235 ! gch1-rlf-1 physical interaction relationship: participates_in CCO:I0018236 ! gch1-gch1 physical interaction relationship: participates_in CCO:I0018237 ! gch1-grfp physical interaction relationship: participates_in CCO:I0018623 ! gch1-hsc70 physical interaction relationship: participates_in CCO:I0018624 ! gch1-rab26 physical interaction relationship: participates_in CCO:I0018625 ! gch1-cb1_1p1 physical interaction relationship: participates_in CCO:I0018626 ! gch1-rlf physical interaction relationship: participates_in CCO:I0018627 ! gch1-aha1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0050753 name: OPRD_HUMAN def: "Delta-type opioid receptor" [UniProtKB:P41143] synonym: "DOR-1" EXACT [UniProtKB:P41143] xref: EMBL:AAA18789.2 xref: EMBL:AAA83426.1 xref: EMBL:CAA15671.1 xref: UniProtKB:P41143 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014874 ! OPRD1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001324 ! delta-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0050755 name: SSR2_HUMAN def: "Somatostatin receptor type 2" [UniProtKB:P30874] synonym: "SRIF-1" EXACT [UniProtKB:P30874] synonym: "SS2R" EXACT [UniProtKB:P30874] xref: EMBL:AAA58248.1 xref: EMBL:AAF42809.1 xref: EMBL:AAF42810.1 xref: EMBL:AAH00256.1 xref: EMBL:AAH09522.1 xref: EMBL:AAH19610.1 xref: EMBL:AAH95495.1 xref: EMBL:AAO92064.1 xref: EMBL:AAV38729.1 xref: EMBL:BAC06126.1 xref: UniProtKB:P30874 xref: UniProtKB:Q4VBP0 xref: UniProtKB:Q96GE0 xref: UniProtKB:Q96TF2 xref: UniProtKB:Q9BWH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015021 ! SSTR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001332 ! somatostatin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0050756 name: Q9H573_HUMAN def: "Opioid receptor, mu 1 (Opioid receptor, mu 1, isoform CRA_a)" [UniProtKB:Q9H573] xref: EMBL:CAC15482.1 xref: EMBL:EAW47704.1 xref: UniProtKB:Q9H573 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014876 ! OPRM1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001326 ! mu-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050758 name: OPRK_HUMAN def: "Kappa-type opioid receptor" [UniProtKB:P41145] synonym: "KOR-1" EXACT [UniProtKB:P41145] xref: EMBL:AAA20985.1 xref: EMBL:AAA56758.1 xref: EMBL:AAA63646.1 xref: EMBL:AAA63906.1 xref: EMBL:AAC50158.1 xref: EMBL:AAH99912.1 xref: EMBL:AAM21070.1 xref: UniProtKB:P41145 xref: UniProtKB:Q499G4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014875 ! OPRK1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001325 ! kappa-opioid receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway [Term] id: CCO:B0050760 name: A6NL10_HUMAN def: "Putative uncharacterized protein OPRL1" [UniProtKB:A6NL10] xref: UniProtKB:A6NL10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014877 ! OPRL1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0002545 ! X-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050761 name: Q8IXB0_HUMAN def: "KOR-3A splice variant" [UniProtKB:Q8IXB0] xref: EMBL:AAO13224.1 xref: UniProtKB:Q8IXB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0002545 ! X-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050764 name: NPBW2_HUMAN def: "Neuropeptides B/W receptor type 2" [UniProtKB:P48146] synonym: "G-protein coupled receptor 8" EXACT [UniProtKB:P48146] xref: EMBL:AAC50198.1 xref: EMBL:CAC17004.1 xref: UniProtKB:P48146 xref: UniProtKB:Q9H4K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014857 ! NPBWR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050772 name: Q8IWW3_HUMAN def: "Mu opioid receptor variant MOR-1C" [UniProtKB:Q8IWW3] xref: EMBL:AAK74190.1 xref: UniProtKB:Q8IWW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015166 ! OPRM_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001326 ! mu-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050781 name: OPRX_HUMAN def: "Nociceptin receptor" [UniProtKB:P41146] synonym: "Kappa-type 3 opioid receptor" EXACT [UniProtKB:P41146] synonym: "KOR-3" EXACT [UniProtKB:P41146] synonym: "Orphanin FQ receptor" EXACT [UniProtKB:P41146] xref: EMBL:AAA84913.1 xref: EMBL:AAA96251.1 xref: EMBL:AAH38433.1 xref: EMBL:AAK11714.1 xref: EMBL:AAL54890.1 xref: EMBL:AAP23195.1 xref: EMBL:CAA54386.1 xref: EMBL:CAC17003.2 xref: UniProtKB:P41146 xref: UniProtKB:Q8WYH9 xref: UniProtKB:Q9H4K4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014877 ! OPRL1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0002545 ! X-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway [Term] id: CCO:B0050782 name: NPBW1_HUMAN def: "Neuropeptides B/W receptor type 1" [UniProtKB:P48145] synonym: "G-protein coupled receptor 7" EXACT [UniProtKB:P48145] xref: EMBL:AAC50197.1 xref: EMBL:AAH69117.1 xref: EMBL:AAI07102.1 xref: EMBL:EAW86722.1 xref: UniProtKB:P48145 xref: UniProtKB:Q6NTC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014856 ! NPBWR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050784 name: Q8IWP3_HUMAN def: "DRG kappa 1 splice variant KOR 1A" [UniProtKB:Q8IWP3] xref: EMBL:AAN87342.1 xref: UniProtKB:Q8IWP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001325 ! kappa-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050785 name: SSR5_HUMAN def: "Somatostatin receptor type 5" [UniProtKB:P35346] synonym: "SS5R" EXACT [UniProtKB:P35346] xref: EMBL:AAA20828.1 xref: EMBL:AAK61266.1 xref: EMBL:BAA04107.1 xref: UniProtKB:P34988 xref: UniProtKB:P35346 xref: UniProtKB:Q9UJI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015024 ! SSTR5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002956 ! regulation of insulin secretion relationship: transforms_into CCO:B0052794 ! SSR5_HUMAN-Phosphoserine325 [Term] id: CCO:B0050788 name: SSR1_HUMAN def: "Somatostatin receptor type 1" [UniProtKB:P30872] synonym: "SRIF-2" EXACT [UniProtKB:P30872] synonym: "SS1R" EXACT [UniProtKB:P30872] xref: EMBL:AAA58247.1 xref: EMBL:AAH35618.1 xref: EMBL:AAP84349.1 xref: UniProtKB:P30872 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015020 ! SSTR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001332 ! somatostatin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000750 ! glutamate signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0050791 name: Q5TBX0_HUMAN def: "Opioid receptor, mu 1 (Opioid receptor, mu 1, isoform CRA_b)" [UniProtKB:Q5TBX0] xref: EMBL:CAI20337.1 xref: EMBL:CAI20458.1 xref: EMBL:EAW47705.1 xref: UniProtKB:Q5TBX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014876 ! OPRM1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001326 ! mu-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050792 name: Q8IWW4_HUMAN def: "Mu opioid receptor variant MOR-1R" [UniProtKB:Q8IWW4] xref: EMBL:AAK74189.1 xref: UniProtKB:Q8IWW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015166 ! OPRM_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_function CCO:F0001326 ! mu-opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0050793 name: SSR4_HUMAN def: "Somatostatin receptor type 4" [UniProtKB:P31391] synonym: "SS4R" EXACT [UniProtKB:P31391] xref: EMBL:AAA36623.1 xref: EMBL:AAA60565.1 xref: EMBL:AAH69063.1 xref: EMBL:AAI17271.1 xref: EMBL:AAI17273.1 xref: EMBL:AAS55648.1 xref: EMBL:BAA04106.1 xref: EMBL:CAB51953.1 xref: EMBL:EAX10170.1 xref: UniProtKB:P31391 xref: UniProtKB:Q17RM1 xref: UniProtKB:Q17RM3 xref: UniProtKB:Q9UIY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015023 ! SSTR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001332 ! somatostatin receptor activity relationship: has_function CCO:F0004369 ! melanin-concentrating hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0050794 name: SSR3_HUMAN def: "Somatostatin receptor type 3" [UniProtKB:P32745] synonym: "SS3R" EXACT [UniProtKB:P32745] synonym: "SSR-28" EXACT [UniProtKB:P32745] xref: EMBL:AAA60592.1 xref: EMBL:AAH96829.1 xref: EMBL:AAP32288.1 xref: EMBL:AAP84354.1 xref: EMBL:CAB45263.1 xref: EMBL:CAG30471.1 xref: UniProtKB:P32745 xref: UniProtKB:Q53ZR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015022 ! SSTR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001332 ! somatostatin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001281 ! nonmotile primary cilium relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000835 ! induction of apoptosis by hormones relationship: transforms_into CCO:B0052791 ! SSR3_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0052792 ! SSR3_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0052793 ! SSR3_HUMAN-Phosphothreonine348 [Term] id: CCO:B0050818 name: WIT1_HUMAN def: "Wilms tumor-associated protein" [UniProtKB:Q06250] synonym: "Wilms tumor upstream neighbor 1 gene protein" EXACT [UniProtKB:Q06250] synonym: "WIT-1" EXACT [UniProtKB:Q06250] xref: EMBL:AAA63269.1 xref: EMBL:CAA49572.1 xref: EMBL:CAC39219.1 xref: UniProtKB:Q06250 xref: UniProtKB:Q96A27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015084 ! WIT1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0050820 name: NT2NL_HUMAN def: "Notch homolog 2 N-terminal-like protein" [UniProtKB:Q7Z3S9] xref: EMBL:AAH10154.3 xref: EMBL:AAH19835.1 xref: EMBL:AAH65219.2 xref: EMBL:AAH84572.1 xref: EMBL:AAH90943.1 xref: EMBL:BAC11381.1 xref: EMBL:CAD97676.1 xref: EMBL:CAH73993.1 xref: EMBL:CAH73994.1 xref: UniProtKB:Q5BKT8 xref: UniProtKB:Q5VTG9 xref: UniProtKB:Q5XG84 xref: UniProtKB:Q6P192 xref: UniProtKB:Q7Z3S9 xref: UniProtKB:Q8NC23 xref: UniProtKB:Q8WUQ9 xref: UniProtKB:Q96FY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014859 ! NOTCH2NL_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0050859 name: C1TC_HUMAN def: "C-1-tetrahydrofolate synthase, cytoplasmic" [UniProtKB:P11586] synonym: "C1-THF synthase" EXACT [UniProtKB:P11586] xref: EMBL:AAA59574.1 xref: EMBL:AAH01014.2 xref: EMBL:AAH09806.1 xref: EMBL:AAH50420.1 xref: UniProtKB:P11586 xref: UniProtKB:Q86VC9 xref: UniProtKB:Q9BVP5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014645 ! MTHFD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: transforms_into CCO:B0052306 ! C1TC_HUMAN-Phosphothreonine786 [Term] id: CCO:B0050867 name: ZN487_HUMAN def: "Zinc finger protein 487" [UniProtKB:B1APH4] xref: EMBL:CAI15018.3 xref: EMBL:CAO03512.1 xref: UniProtKB:B1APH4 xref: UniProtKB:B1APH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015091 ! ZNF487_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0050955 name: MAP2_HUMAN def: "Microtubule-associated protein 2" [UniProtKB:P11137] synonym: "MAP-2" EXACT [UniProtKB:P11137] xref: EMBL:AAA03354.1 xref: EMBL:AAA59552.1 xref: EMBL:AAB48097.1 xref: EMBL:AAB48098.1 xref: UniProtKB:P11137 xref: UniProtKB:Q99975 xref: UniProtKB:Q99976 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014816 ! MAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: transforms_into CCO:B0052533 ! MAP2_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0052534 ! MAP2_HUMAN-Phosphoserine610 relationship: transforms_into CCO:B0052535 ! MAP2_HUMAN-Phosphoserine629 relationship: transforms_into CCO:B0052536 ! MAP2_HUMAN-Phosphoserine654 relationship: transforms_into CCO:B0052537 ! MAP2_HUMAN-Phosphoserine729 relationship: transforms_into CCO:B0052538 ! MAP2_HUMAN-Phosphoserine736 relationship: transforms_into CCO:B0052539 ! MAP2_HUMAN-Phosphotyrosine745 relationship: transforms_into CCO:B0052540 ! MAP2_HUMAN-Phosphoserine821 relationship: transforms_into CCO:B0052541 ! MAP2_HUMAN-Phosphoserine833 relationship: transforms_into CCO:B0052542 ! MAP2_HUMAN-Phosphoserine1155 relationship: transforms_into CCO:B0052543 ! MAP2_HUMAN-Phosphoserine1347 relationship: transforms_into CCO:B0052544 ! MAP2_HUMAN-Phosphoserine1353 relationship: transforms_into CCO:B0052545 ! MAP2_HUMAN-Phosphoserine1421 relationship: transforms_into CCO:B0052546 ! MAP2_HUMAN-Phosphothreonine1440 relationship: transforms_into CCO:B0052547 ! MAP2_HUMAN-Phosphoserine1480 relationship: transforms_into CCO:B0052548 ! MAP2_HUMAN-Phosphoserine1534 relationship: transforms_into CCO:B0052549 ! MAP2_HUMAN-Phosphoserine1591 relationship: transforms_into CCO:B0052550 ! MAP2_HUMAN-Phosphothreonine1594 relationship: transforms_into CCO:B0052551 ! MAP2_HUMAN-Phosphothreonine1595 relationship: transforms_into CCO:B0052552 ! MAP2_HUMAN-Phosphothreonine1602 relationship: transforms_into CCO:B0052553 ! MAP2_HUMAN-Phosphothreonine1605 relationship: transforms_into CCO:B0052554 ! MAP2_HUMAN-Phosphoserine1608 relationship: transforms_into CCO:B0052555 ! MAP2_HUMAN-Phosphoserine1611 relationship: transforms_into CCO:B0052556 ! MAP2_HUMAN-Phosphothreonine1613 relationship: transforms_into CCO:B0052557 ! MAP2_HUMAN-Phosphothreonine1616 relationship: transforms_into CCO:B0052558 ! MAP2_HUMAN-Phosphothreonine1649 relationship: transforms_into CCO:B0052559 ! MAP2_HUMAN-Phosphoserine1782 relationship: transforms_into CCO:B0052560 ! MAP2_HUMAN-Phosphoserine1790 relationship: transforms_into CCO:B0052561 ! MAP2_HUMAN-Phosphoserine1798 relationship: transforms_into CCO:B0052562 ! MAP2_HUMAN-Phosphoserine1799 relationship: transforms_into CCO:B0052563 ! MAP2_HUMAN-Phosphoserine1800 relationship: transforms_into CCO:B0052564 ! MAP2_HUMAN-Phosphoserine1802 [Term] id: CCO:B0050997 name: MFN2_HUMAN def: "Mitofusin-2" [UniProtKB:O95140] synonym: "EC 3.6.5.-" EXACT [UniProtKB:O95140] synonym: "Transmembrane GTPase MFN2" EXACT [UniProtKB:O95140] xref: EMBL:AAD02058.2 xref: EMBL:AAH17061.1 xref: EMBL:AAK18728.1 xref: EMBL:BAA34389.2 xref: EMBL:CAB70866.2 xref: EMBL:CAI19087.2 xref: EMBL:CAI19088.2 xref: UniProtKB:O95140 xref: UniProtKB:O95572 xref: UniProtKB:Q5JXC3 xref: UniProtKB:Q5JXC4 xref: UniProtKB:Q9H131 xref: UniProtKB:Q9NSX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014825 ! MFN2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: located_in CCO:C0001193 ! intrinsic to mitochondrial outer membrane relationship: participates_in CCO:P0002700 ! negative regulation of Ras protein signal transduction relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation [Term] id: CCO:B0051010 name: SPT4H_HUMAN def: "Transcription elongation factor SPT4" [UniProtKB:P63272] synonym: "DRB sensitivity-inducing factor small subunit" EXACT [UniProtKB:P63272] synonym: "DSIF p14" EXACT [UniProtKB:P63272] synonym: "DSIF small subunit" EXACT [UniProtKB:P63272] synonym: "hSPT4" EXACT [UniProtKB:P63272] xref: EMBL:AAB07814.1 xref: EMBL:AAB18674.1 xref: EMBL:AAB18675.1 xref: EMBL:AAH02802.1 xref: EMBL:BAC85230.1 xref: EMBL:CAG28591.1 xref: UniProtKB:P63272 xref: UniProtKB:Q16550 xref: UniProtKB:Q62387 xref: UniProtKB:Q6ZP89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015013 ! SUPT4H1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001750 ! negative transcription elongation factor activity relationship: has_function CCO:F0001753 ! positive transcription elongation factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0020676 ! supt4h1-anxa5 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0051023 name: PGRC1_HUMAN def: "Membrane-associated progesterone receptor component 1" [UniProtKB:O00264] synonym: "mPR" EXACT [UniProtKB:O00264] xref: EMBL:AAH34238.1 xref: EMBL:CAA73248.1 xref: EMBL:CAB65109.1 xref: UniProtKB:O00264 xref: UniProtKB:Q9UGJ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014915 ! PGRMC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: transforms_into CCO:B0052621 ! PGRC1_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0052622 ! PGRC1_HUMAN-Phosphothreonine178 relationship: transforms_into CCO:B0052623 ! PGRC1_HUMAN-Phosphotyrosine180 relationship: transforms_into CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 [Term] id: CCO:B0051188 name: SYNJ2_HUMAN def: "Synaptojanin-2" [UniProtKB:O15056] synonym: "EC 3.1.3.36" EXACT [UniProtKB:O15056] synonym: "Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2" EXACT [UniProtKB:O15056] xref: EMBL:AAD02178.1 xref: EMBL:AAG46036.1 xref: EMBL:AAH43277.1 xref: EMBL:AAN73051.1 xref: EMBL:BAA20805.2 xref: EMBL:CAI12978.1 xref: EMBL:CAI12983.1 xref: EMBL:CAI12984.1 xref: UniProtKB:O15056 xref: UniProtKB:Q5TA13 xref: UniProtKB:Q5TA16 xref: UniProtKB:Q5TA19 xref: UniProtKB:Q86XK0 xref: UniProtKB:Q8IZA8 xref: UniProtKB:Q9H226 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015028 ! SYNJ2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017281 ! synj2-itsn2 physical interaction relationship: transforms_into CCO:B0071062 ! SYNJ2_HUMAN-Phosphotyrosine130 [Term] id: CCO:B0051192 name: CNPY4_HUMAN def: "Protein canopy homolog 4 precursor" [UniProtKB:Q8N129] xref: EMBL:AAH19903.2 xref: EMBL:AAH32339.1 xref: EMBL:AAQ89458.1 xref: EMBL:BAC11680.1 xref: EMBL:EAL23850.1 xref: UniProtKB:Q8N129 xref: UniProtKB:Q8WUN9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014680 ! CNPY4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0020507 ! arf4l-mgc40499 physical interaction [Term] id: CCO:B0051199 name: RP1BL_HUMAN def: "Ras-related protein Rap-1b-like protein precursor" [UniProtKB:A6NIZ1] xref: EMBL:EAW95773.1 xref: UniProtKB:A6NIZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0052706 ! RP1BL_HUMAN-ADP-ribosylserine39 relationship: transforms_into CCO:B0052707 ! RP1BL_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0052708 ! RP1BL_HUMAN-Cysteine methyl ester181 [Term] id: CCO:B0051232 name: CLPT1_HUMAN def: "Cleft lip and palate transmembrane protein 1" [UniProtKB:O96005] xref: EMBL:AAC97420.1 xref: EMBL:AAC98151.1 xref: EMBL:AAH04865.1 xref: EMBL:AAH12359.1 xref: EMBL:AAP35926.1 xref: EMBL:BAD97273.1 xref: UniProtKB:O96005 xref: UniProtKB:Q53ET6 xref: UniProtKB:Q9BSS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014675 ! CLPTM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001769 ! regulation of T cell differentiation in the thymus relationship: transforms_into CCO:B0052342 ! CLPT1_HUMAN-Phosphothreonine213 relationship: transforms_into CCO:B0052343 ! CLPT1_HUMAN-Phosphothreonine216 [Term] id: CCO:B0051349 name: GBRL2_HUMAN def: "Gamma-aminobutyric acid receptor-associated protein-like 2" [UniProtKB:P60520] synonym: "GABA(A) receptor-associated protein-like 2" EXACT [UniProtKB:P60520] synonym: "Ganglioside expression factor 2" EXACT [UniProtKB:P60520] synonym: "GATE-16" EXACT [UniProtKB:P60520] synonym: "GEF-2" EXACT [UniProtKB:P60520] synonym: "General protein transport factor p16" EXACT [UniProtKB:P60520] synonym: "Golgi-associated ATPase enhancer of 16 kDa" EXACT [UniProtKB:P60520] synonym: "MAP1 light chain 3-related protein" EXACT [UniProtKB:P60520] xref: EMBL:AAD27779.1 xref: EMBL:AAH05985.1 xref: EMBL:AAH14594.1 xref: EMBL:AAH29601.1 xref: EMBL:AAK20400.1 xref: EMBL:BAB21548.1 xref: EMBL:CAA09249.1 xref: UniProtKB:O08765 xref: UniProtKB:P60520 xref: UniProtKB:Q9DCP8 xref: UniProtKB:Q9UQF7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014739 ! GABARAPL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014995 ! gabarapl2-mlx physical interaction relationship: participates_in CCO:I0015037 ! gabarapl2-tbc1d5 physical interaction relationship: participates_in CCO:I0015042 ! gabarapl2-sqstm1 physical interaction relationship: participates_in CCO:I0015338 ! bcl2l13-gabarapl2 physical interaction relationship: participates_in CCO:I0017409 ! atg7-gabarapl2 direct interaction relationship: transforms_into CCO:B0052399 ! GBRL2_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0052400 ! GBRL2_HUMAN-Phosphoserine39 [Term] id: CCO:B0051353 name: GBRL1_HUMAN def: "Gamma-aminobutyric acid receptor-associated protein-like 1" [UniProtKB:Q9H0R8] synonym: "Early estrogen-regulated protein" EXACT [UniProtKB:Q9H0R8] synonym: "GABA(A) receptor-associated protein-like 1" EXACT [UniProtKB:Q9H0R8] synonym: "GEC-1" EXACT [UniProtKB:Q9H0R8] synonym: "Glandular epithelial cell protein 1" EXACT [UniProtKB:Q9H0R8] xref: EMBL:AAH09309.1 xref: EMBL:AAH28315.1 xref: EMBL:AAK20399.1 xref: EMBL:AAK55962.1 xref: EMBL:CAB66611.1 xref: EMBL:CAG38511.1 xref: EMBL:EAW96164.1 xref: UniProtKB:Q6FIE6 xref: UniProtKB:Q9H0R8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014738 ! GABARAPL1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_function CCO:F0008016 ! GABA receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000358 ! autophagic vacuole relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015297 ! gabarapl1-sqstm1 physical interaction [Term] id: CCO:B0051370 name: FIBP_HUMAN def: "Acidic fibroblast growth factor intracellular-binding protein" [UniProtKB:O43427] synonym: "aFGF intracellular-binding protein" EXACT [UniProtKB:O43427] synonym: "FGF-1 intracellular-binding protein" EXACT [UniProtKB:O43427] xref: EMBL:AAC97140.2 xref: EMBL:AAD51694.1 xref: EMBL:AAD51695.1 xref: EMBL:AAD51696.1 xref: EMBL:AAG01396.1 xref: EMBL:AAG01397.1 xref: EMBL:AAH14388.1 xref: EMBL:AAH17448.1 xref: EMBL:CAG33030.1 xref: UniProtKB:O43427 xref: UniProtKB:Q6IBQ3 xref: UniProtKB:Q9HD65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014731 ! FIBP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003590 ! fibroblast growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0051378 name: Q29675_HUMAN def: "MHC class II transactivator CIITA" [UniProtKB:Q29675] xref: EMBL:AAA88862.1 xref: UniProtKB:Q29675 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0051380 name: C2TA_HUMAN def: "MHC class II transactivator" [UniProtKB:P33076] synonym: "CIITA" EXACT [UniProtKB:P33076] xref: EMBL:AAA88861.1 xref: EMBL:CAA52354.1 xref: UniProtKB:P33076 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014647 ! CIITA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0051381 name: A0N0N9_HUMAN def: "Class II, major histocompatibility complex, transactivator" [UniProtKB:A0N0N9] xref: EMBL:ABK41930.1 xref: UniProtKB:A0N0N9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014647 ! CIITA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0051382 name: Q8SNB7_HUMAN def: "MHC class II transactivator CIITAlo" [UniProtKB:Q8SNB7] xref: EMBL:AAM15724.1 xref: UniProtKB:Q8SNB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0051384 name: Q8SNB8_HUMAN def: "MHC class II transactivator CIITAmed" [UniProtKB:Q8SNB8] synonym: "Class II, major histocompatibility complex, transactivator, isoform CRA_e" EXACT [UniProtKB:Q8SNB8] xref: EMBL:AAM15723.1 xref: EMBL:EAW85173.1 xref: UniProtKB:Q8SNB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014647 ! CIITA_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0051400 name: YS018_HUMAN def: "Probable Ras GTPase-activating protein FLJ21438" [UniProtKB:Q86YV0] xref: EMBL:AAH30281.1 xref: EMBL:BAB15064.1 xref: EMBL:BAC56928.1 xref: UniProtKB:Q86YV0 xref: UniProtKB:Q8N2T9 xref: UniProtKB:Q9H735 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0051401 name: B1AKC7_HUMAN def: "RAS protein activator like 2" [UniProtKB:B1AKC7] xref: EMBL:CAH71462.1 xref: EMBL:CAH72349.1 xref: EMBL:CAI21910.1 xref: EMBL:CAI22692.1 xref: UniProtKB:B1AKC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007878 ! RASAL2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0051475 name: MOT3_HUMAN def: "Monocarboxylate transporter 3" [UniProtKB:O95907] synonym: "MCT 3" EXACT [UniProtKB:O95907] synonym: "Solute carrier family 16 member 8" EXACT [UniProtKB:O95907] xref: EMBL:AAF03489.1 xref: EMBL:AAF03565.1 xref: EMBL:CAB37479.1 xref: UniProtKB:O95907 xref: UniProtKB:Q9UBE2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014836 ! SLC16A8_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0002606 ! lactate transmembrane transporter activity relationship: has_function CCO:F0002742 ! symporter activity relationship: has_function CCO:F0002788 ! secondary active monocarboxylate transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020424 ! rab1a-slc16a8 physical interaction [Term] id: CCO:B0051549 name: IF5_HUMAN def: "Eukaryotic translation initiation factor 5" [UniProtKB:P55010] synonym: "eIF-5" EXACT [UniProtKB:P55010] xref: EMBL:AAC50572.1 xref: EMBL:AAH07728.1 xref: EMBL:AAH32866.1 xref: EMBL:BAB15593.1 xref: EMBL:CAB45711.1 xref: UniProtKB:P55010 xref: UniProtKB:Q9H5N2 xref: UniProtKB:Q9UG48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014774 ! EIF5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0052443 ! IF5_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0052444 ! IF5_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0052445 ! IF5_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0052446 ! IF5_HUMAN-Phosphotyrosine405 relationship: transforms_into CCO:B0052447 ! IF5_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0067050 ! IF5_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0067051 ! IF5_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0067052 ! IF5_HUMAN-Phosphoserine419 [Term] id: CCO:B0051561 name: Q659G3_HUMAN def: "Putative uncharacterized protein DKFZp564M2223" [UniProtKB:Q659G3] synonym: "SRP9 protein" EXACT [UniProtKB:Q659G3] xref: EMBL:AAI06006.1 xref: EMBL:CAH56414.1 xref: UniProtKB:Q659G3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015187 ! DKFZp564M2223_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001826 ! 7S RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0002002 ! signal recognition particle relationship: participates_in CCO:P0002601 ! negative regulation of translational elongation [Term] id: CCO:B0051562 name: SRP09_HUMAN def: "Signal recognition particle 9 kDa protein" [UniProtKB:P49458] synonym: "SRP9" EXACT [UniProtKB:P49458] xref: EMBL:AAA70170.1 xref: EMBL:AAH08443.1 xref: EMBL:AAH15094.1 xref: EMBL:AAH22415.1 xref: EMBL:AAH66957.1 xref: UniProtKB:P49458 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015019 ! SRP9_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001367 ! signal recognition particle binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001826 ! 7S RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000366 ! signal recognition particle receptor complex relationship: located_in CCO:C0000367 ! signal recognition particle, endoplasmic reticulum targeting relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002002 ! signal recognition particle relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0002601 ! negative regulation of translational elongation [Term] id: CCO:B0051564 name: Q6NVX0_HUMAN def: "SRP9 protein" [UniProtKB:Q6NVX0] synonym: "Signal recognition particle 9 kDa isoform" EXACT [UniProtKB:Q6NVX0] synonym: "Signal recognition particle 9kDa, isoform CRA_b" EXACT [UniProtKB:Q6NVX0] xref: EMBL:AAH67845.1 xref: EMBL:ABP02070.1 xref: EMBL:EAW69751.1 xref: UniProtKB:Q6NVX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015019 ! SRP9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001826 ! 7S RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0002002 ! signal recognition particle relationship: participates_in CCO:P0002601 ! negative regulation of translational elongation [Term] id: CCO:B0051565 name: RTF1_HUMAN def: "RNA polymerase-associated protein RTF1 homolog" [UniProtKB:Q92541] xref: EMBL:AAH15052.1 xref: EMBL:BAA13382.2 xref: UniProtKB:Q92541 xref: UniProtKB:Q96BX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014987 ! RTF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0052711 ! RTF1_HUMAN-Phosphoserine657 [Term] id: CCO:B0051572 name: RIOK3_HUMAN def: "Serine/threonine-protein kinase RIO3" [UniProtKB:O14730] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O14730] synonym: "RIO kinase 3" EXACT [UniProtKB:O14730] synonym: "sudD homolog" EXACT [UniProtKB:O14730] xref: EMBL:AAC26080.1 xref: EMBL:AAH39729.1 xref: UniProtKB:O14730 xref: UniProtKB:Q8IXN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014977 ! RIOK3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000695 ! chromosome segregation [Term] id: CCO:B0051606 name: VILL_HUMAN def: "Villin-like protein" [UniProtKB:O15195] xref: EMBL:AAH00243.1 xref: EMBL:AAH04300.1 xref: EMBL:BAA21668.1 xref: EMBL:EAW64506.1 xref: UniProtKB:A8MZP1 xref: UniProtKB:O15195 xref: UniProtKB:Q9BT80 xref: UniProtKB:Q9BWH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015078 ! VILL_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping [Term] id: CCO:B0051611 name: GELS_HUMAN def: "Gelsolin precursor" [UniProtKB:P06396] synonym: "Actin-depolymerizing factor" EXACT [UniProtKB:P06396] synonym: "ADF" EXACT [UniProtKB:P06396] synonym: "AGEL" EXACT [UniProtKB:P06396] synonym: "Brevin" EXACT [UniProtKB:P06396] xref: EMBL:AAH17491.1 xref: EMBL:AAH26033.1 xref: EMBL:CAA28000.1 xref: UniProtKB:P06396 xref: UniProtKB:Q8WVV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014742 ! GSN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0020015 ! gsn-tom1l1 physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0052401 ! GELS_HUMAN-Phosphotyrosine86 relationship: transforms_into CCO:B0052402 ! GELS_HUMAN-Phosphotyrosine409 relationship: transforms_into CCO:B0052403 ! GELS_HUMAN-Phosphotyrosine465 relationship: transforms_into CCO:B0052404 ! GELS_HUMAN-Phosphotyrosine603 relationship: transforms_into CCO:B0052405 ! GELS_HUMAN-Phosphotyrosine651 [Term] id: CCO:B0051612 name: AVIL_HUMAN def: "Advillin" [UniProtKB:O75366] synonym: "p92" EXACT [UniProtKB:O75366] xref: EMBL:AAC25051.1 xref: UniProtKB:O75366 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014640 ! AVIL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0052302 ! AVIL_HUMAN-Phosphotyrosine85 relationship: transforms_into CCO:B0052303 ! AVIL_HUMAN-Phosphotyrosine758 [Term] id: CCO:B0051613 name: VILI_HUMAN def: "Villin-1" [UniProtKB:P09327] xref: EMBL:CAA28355.1 xref: EMBL:CAA31386.1 xref: UniProtKB:P09327 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015077 ! VIL1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping [Term] id: CCO:B0051620 name: ADSV_HUMAN def: "Adseverin" [UniProtKB:Q9Y6U3] synonym: "Scinderin" EXACT [UniProtKB:Q9Y6U3] xref: EMBL:AAD15423.1 xref: EMBL:AAH21090.1 xref: EMBL:AAK60494.1 xref: EMBL:BAB55361.1 xref: EMBL:BAB67798.1 xref: EMBL:BAC11416.1 xref: UniProtKB:Q8NBZ6 xref: UniProtKB:Q8WU97 xref: UniProtKB:Q96JC7 xref: UniProtKB:Q96PY2 xref: UniProtKB:Q9Y6U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014620 ! SCIN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016663 ! map3k3-scin physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002468 ! positive regulation of megakaryocyte differentiation relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0052276 ! ADSV_HUMAN-Phosphotyrosine102 relationship: transforms_into CCO:B0052277 ! ADSV_HUMAN-Phosphotyrosine599 [Term] id: CCO:B0051700 name: S10A7_HUMAN def: "Protein S100-A7" [UniProtKB:P31151] synonym: "Psoriasin" EXACT [UniProtKB:P31151] synonym: "S100 calcium-binding protein A7" EXACT [UniProtKB:P31151] xref: EMBL:AAA60210.1 xref: EMBL:AAH34687.1 xref: EMBL:CAC20409.1 xref: EMBL:CAG46961.1 xref: EMBL:CAI19502.1 xref: EMBL:FAA00017.1 xref: UniProtKB:P31151 xref: UniProtKB:Q5SY67 xref: UniProtKB:Q6FGE3 xref: UniProtKB:Q9H1E2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014991 ! S100A7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0016760 ! map3k3-s100a7 physical interaction relationship: transforms_into CCO:B0052719 ! S10A7_HUMAN-N-acetylserine2 [Term] id: CCO:B0051710 name: TMCC2_HUMAN def: "Transmembrane and coiled-coil domains protein 2" [UniProtKB:O75069] synonym: "Cerebral protein 11" EXACT [UniProtKB:O75069] xref: EMBL:BAA32326.3 xref: EMBL:BAB46924.1 xref: EMBL:BAD18566.1 xref: UniProtKB:O75069 xref: UniProtKB:Q6ZN09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015048 ! TMCC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020636 ! ptov1-tmcc2 physical interaction relationship: transforms_into CCO:B0052848 ! TMCC2_HUMAN-Phosphoserine464 relationship: transforms_into CCO:B0052849 ! TMCC2_HUMAN-Phosphothreonine466 relationship: transforms_into CCO:B0052850 ! TMCC2_HUMAN-Phosphoserine470 relationship: transforms_into CCO:B0052851 ! TMCC2_HUMAN-Phosphoserine481 [Term] id: CCO:B0051775 name: ZN277_HUMAN def: "Zinc finger protein 277" [UniProtKB:Q9NRM2] xref: EMBL:AAF85941.1 xref: UniProtKB:Q9NRM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015090 ! ZNF277_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019140 ! coil-znf277 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0051810 name: IRS1_HUMAN def: "Insulin receptor substrate 1" [UniProtKB:P35568] synonym: "IRS-1" EXACT [UniProtKB:P35568] xref: EMBL:AAB21608.1 xref: EMBL:AAB27175.1 xref: EMBL:AAH53895.1 xref: UniProtKB:P35568 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014779 ! IRS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017635 ! irs1-npm_alk physical interaction relationship: participates_in CCO:I0018176 ! insr-irs1-1 physical interaction relationship: participates_in CCO:I0018177 ! insr-irs1-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0002225 ! protein kinase B signaling cascade relationship: participates_in CCO:P0002755 ! insulin-like growth factor receptor signaling pathway relationship: transforms_into CCO:B0052453 ! IRS1_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0052454 ! IRS1_HUMAN-Phosphotyrosine46 relationship: transforms_into CCO:B0052455 ! IRS1_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0052456 ! IRS1_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0052457 ! IRS1_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0052458 ! IRS1_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0052459 ! IRS1_HUMAN-Phosphotyrosine465 relationship: transforms_into CCO:B0052460 ! IRS1_HUMAN-Phosphoserine531 relationship: transforms_into CCO:B0052461 ! IRS1_HUMAN-Phosphotyrosine612 relationship: transforms_into CCO:B0052462 ! IRS1_HUMAN-Phosphoserine629 relationship: transforms_into CCO:B0052463 ! IRS1_HUMAN-Phosphotyrosine632 relationship: transforms_into CCO:B0052464 ! IRS1_HUMAN-Phosphoserine636 relationship: transforms_into CCO:B0052465 ! IRS1_HUMAN-Phosphotyrosine662 relationship: transforms_into CCO:B0052466 ! IRS1_HUMAN-Phosphoserine794 relationship: transforms_into CCO:B0052467 ! IRS1_HUMAN-Phosphotyrosine896 relationship: transforms_into CCO:B0052468 ! IRS1_HUMAN-Phosphotyrosine941 relationship: transforms_into CCO:B0052469 ! IRS1_HUMAN-Phosphotyrosine989 relationship: transforms_into CCO:B0052470 ! IRS1_HUMAN-Phosphoserine1101 relationship: transforms_into CCO:B0052471 ! IRS1_HUMAN-Phosphoserine1145 relationship: transforms_into CCO:B0052472 ! IRS1_HUMAN-Phosphotyrosine1179 relationship: transforms_into CCO:B0052473 ! IRS1_HUMAN-Phosphoserine1223 relationship: transforms_into CCO:B0052474 ! IRS1_HUMAN-Phosphotyrosine1229 [Term] id: CCO:B0051815 name: IRS4_HUMAN def: "Insulin receptor substrate 4" [UniProtKB:O14654] synonym: "160 kDa phosphotyrosine protein" EXACT [UniProtKB:O14654] synonym: "IRS-4" EXACT [UniProtKB:O14654] synonym: "PY160" EXACT [UniProtKB:O14654] xref: EMBL:AAC51738.1 xref: EMBL:CAB90290.1 xref: EMBL:EAX02682.1 xref: UniProtKB:O14654 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014781 ! IRS4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0016613 ! map3k1-da24a23_2 physical interaction relationship: participates_in CCO:I0017043 ! tnfrsf1b-da24a23_2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0052500 ! IRS4_HUMAN-Phosphotyrosine921 relationship: transforms_into CCO:B0067154 ! IRS4_HUMAN-Phosphotyrosine1038 [Term] id: CCO:B0051832 name: Q8WU57_HUMAN def: "SELI protein" [UniProtKB:Q8WU57] synonym: "Putative uncharacterized protein tmp_locus_24" EXACT [UniProtKB:Q8WU57] synonym: "Selenoprotein I" EXACT [UniProtKB:Q8WU57] xref: EMBL:AAH21229.1 xref: EMBL:AAY14646.1 xref: EMBL:EAX00693.1 xref: UniProtKB:Q8WU57 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0015002 ! SELI_human relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015673 ! ewsr1-seli physical interaction [Term] id: CCO:B0051877 name: OR8D2_HUMAN def: "Olfactory receptor 8D2" [UniProtKB:Q9GZM6] synonym: "Olfactory receptor-like protein JCG2" EXACT [UniProtKB:Q9GZM6] xref: EMBL:AAG43386.1 xref: EMBL:AAG43387.1 xref: UniProtKB:Q9GZM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014888 ! OR8D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0051880 name: OR8G1_HUMAN def: "Olfactory receptor 8G1" [UniProtKB:Q15617] synonym: "Olfactory receptor OR11-281" EXACT [UniProtKB:Q15617] synonym: "Olfactory receptor TPCR25" EXACT [UniProtKB:Q15617] xref: EMBL:AAK94992.1 xref: EMBL:BAC06159.1 xref: EMBL:CAA61819.1 xref: EMBL:DAA04821.1 xref: UniProtKB:Q15617 xref: UniProtKB:Q8NG88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014890 ! OR8G1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0051882 name: OR8G2_HUMAN def: "Olfactory receptor 8G2" [UniProtKB:Q15614] synonym: "Olfactory receptor OR11-297" EXACT [UniProtKB:Q15614] synonym: "Olfactory receptor TPCR120" EXACT [UniProtKB:Q15614] xref: EMBL:CAA61816.1 xref: EMBL:DAA04822.1 xref: UniProtKB:Q15614 xref: UniProtKB:Q6IF38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014891 ! OR8G2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0051883 name: OR8U9_HUMAN def: "Olfactory receptor 8U9" [UniProtKB:P0C7N5] xref: EMBL:EAW73667.1 xref: UniProtKB:P0C7N5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014899 ! OR8U9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0051887 name: O5AK2_HUMAN def: "Olfactory receptor 5AK2" [UniProtKB:Q8NH90] xref: EMBL:BAC05747.1 xref: UniProtKB:Q8NH90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014864 ! OR5AK2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0051892 name: OR8U8_HUMAN def: "Olfactory receptor 8U8" [UniProtKB:P0C7N1] xref: EMBL:EAW73711.1 xref: UniProtKB:P0C7N1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014898 ! OR8U8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0051893 name: O5AP2_HUMAN def: "Olfactory receptor 5AP2" [UniProtKB:Q8NGF4] xref: EMBL:BAC06072.1 xref: UniProtKB:Q8NGF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014865 ! OR5AP2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0051938 name: EHMT2_HUMAN def: "Histone-lysine N-methyltransferase, H3 lysine-9 specific 3" [UniProtKB:Q96KQ7] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q96KQ7] synonym: "Euchromatic histone-lysine N-methyltransferase 2" EXACT [UniProtKB:Q96KQ7] synonym: "H3-K9-HMTase 3" EXACT [UniProtKB:Q96KQ7] synonym: "Histone H3-K9 methyltransferase 3" EXACT [UniProtKB:Q96KQ7] synonym: "HLA-B-associated transcript 8" EXACT [UniProtKB:Q96KQ7] synonym: "Lysine N-methyltransferase 1C" EXACT [UniProtKB:Q96KQ7] synonym: "Protein G9a" EXACT [UniProtKB:Q96KQ7] xref: EMBL:AAD21811.1 xref: EMBL:AAD21812.1 xref: EMBL:AAH02686.2 xref: EMBL:AAH09351.1 xref: EMBL:AAH18718.1 xref: EMBL:AAH20970.2 xref: EMBL:BAB63294.1 xref: EMBL:BAB63295.1 xref: EMBL:BAB71314.1 xref: EMBL:CAA49491.1 xref: EMBL:CAC86666.1 xref: UniProtKB:Q14349 xref: UniProtKB:Q6PK06 xref: UniProtKB:Q96KQ7 xref: UniProtKB:Q96MH5 xref: UniProtKB:Q96QD0 xref: UniProtKB:Q9UQL8 xref: UniProtKB:Q9Y331 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0014709 ! EHMT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015155 ! ehmt2-hgs physical interaction relationship: participates_in CCO:I0015401 ! ehmt2-klf6 physical interaction relationship: participates_in CCO:I0015604 ! ehmt2-thap7 physical interaction relationship: participates_in CCO:I0015642 ! ehmt2-klf12 physical interaction relationship: transforms_into CCO:B0052366 ! EHMT2_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0052367 ! EHMT2_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0052368 ! EHMT2_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0052369 ! EHMT2_HUMAN-Phosphothreonine555 relationship: transforms_into CCO:B0052370 ! EHMT2_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0065987 ! EHMT2_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0065988 ! EHMT2_HUMAN-Phosphothreonine1210 [Term] id: CCO:B0052260 name: 2A5G_HUMAN-Phosphotyrosine348 def: "Protein 2A5G_HUMAN with the residue 348 substituted with Phosphotyrosine" [UniProtKB:Q13362] xref: UniProtKB:Q13362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0026004 ! 2A5G_HUMAN [Term] id: CCO:B0052261 name: 2A5G_HUMAN-Phosphotyrosine349 def: "Protein 2A5G_HUMAN with the residue 349 substituted with Phosphotyrosine" [UniProtKB:Q13362] xref: UniProtKB:Q13362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026004 ! 2A5G_HUMAN [Term] id: CCO:B0052262 name: 2A5G_HUMAN-Phosphotyrosine354 def: "Protein 2A5G_HUMAN with the residue 354 substituted with Phosphotyrosine" [UniProtKB:Q13362] xref: UniProtKB:Q13362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026004 ! 2A5G_HUMAN [Term] id: CCO:B0052274 name: ABL2_HUMAN-Phosphoserine71 def: "Protein ABL2_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0052276 name: ADSV_HUMAN-Phosphotyrosine102 def: "Protein ADSV_HUMAN with the residue 102 substituted with Phosphotyrosine" [UniProtKB:Q9Y6U3] comment: By similarity xref: UniProtKB:Q9Y6U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051620 ! ADSV_HUMAN [Term] id: CCO:B0052277 name: ADSV_HUMAN-Phosphotyrosine599 def: "Protein ADSV_HUMAN with the residue 599 substituted with Phosphotyrosine" [UniProtKB:Q9Y6U3] comment: By similarity xref: UniProtKB:Q9Y6U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000215 ! phosphatidylserine binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_function CCO:F0001669 ! phosphatidylinositol-4,5-bisphosphate binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000489 ! cell cortex relationship: transformation_of CCO:B0051620 ! ADSV_HUMAN [Term] id: CCO:B0052286 name: ARI5B_HUMAN-Phosphoserine1002 def: "Protein ARI5B_HUMAN with the residue 1002 substituted with Phosphoserine" [UniProtKB:Q14865] xref: UniProtKB:Q14865 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0050679 ! ARI5B_HUMAN [Term] id: CCO:B0052287 name: ARP3B_HUMAN-N-acetylalanine2 def: "Protein ARP3B_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9P1U1] comment: By similarity xref: UniProtKB:Q9P1U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049611 ! ARP3B_HUMAN [Term] id: CCO:B0052288 name: ARP3B_HUMAN-Phosphotyrosine231 def: "Protein ARP3B_HUMAN with the residue 231 substituted with Phosphotyrosine" [UniProtKB:Q9P1U1] comment: By similarity xref: UniProtKB:Q9P1U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049611 ! ARP3B_HUMAN [Term] id: CCO:B0052289 name: ARP3B_HUMAN-Phosphoserine418 def: "Protein ARP3B_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:Q9P1U1] comment: By similarity xref: UniProtKB:Q9P1U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049611 ! ARP3B_HUMAN [Term] id: CCO:B0052290 name: ARS2_HUMAN-Phosphotyrosine8 def: "Protein ARS2_HUMAN with the residue 8 substituted with Phosphotyrosine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052291 name: ARS2_HUMAN-Phosphoserine67 def: "Protein ARS2_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052292 name: ARS2_HUMAN-Phosphoserine74 def: "Protein ARS2_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052293 name: ARS2_HUMAN-Phosphoserine493 def: "Protein ARS2_HUMAN with the residue 493 substituted with Phosphoserine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052294 name: ARS2_HUMAN-Phosphoserine540 def: "Protein ARS2_HUMAN with the residue 540 substituted with Phosphoserine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052295 name: ARS2_HUMAN-Phosphothreonine544 def: "Protein ARS2_HUMAN with the residue 544 substituted with Phosphothreonine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052296 name: ARS2_HUMAN-Phosphotyrosine624 def: "Protein ARS2_HUMAN with the residue 624 substituted with Phosphotyrosine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052297 name: ARS2_HUMAN-Phosphotyrosine625 def: "Protein ARS2_HUMAN with the residue 625 substituted with Phosphotyrosine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0052301 name: ATX3_HUMAN-Phosphoserine219 def: "Protein ATX3_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:P54252] comment: By similarity xref: UniProtKB:P54252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049689 ! ATX3_HUMAN [Term] id: CCO:B0052302 name: AVIL_HUMAN-Phosphotyrosine85 def: "Protein AVIL_HUMAN with the residue 85 substituted with Phosphotyrosine" [UniProtKB:O75366] comment: By similarity xref: UniProtKB:O75366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051612 ! AVIL_HUMAN [Term] id: CCO:B0052303 name: AVIL_HUMAN-Phosphotyrosine758 def: "Protein AVIL_HUMAN with the residue 758 substituted with Phosphotyrosine" [UniProtKB:O75366] comment: By similarity xref: UniProtKB:O75366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0051612 ! AVIL_HUMAN [Term] id: CCO:B0052306 name: C1TC_HUMAN-Phosphothreonine786 def: "Protein C1TC_HUMAN with the residue 786 substituted with Phosphothreonine" [UniProtKB:P11586] comment: By similarity xref: UniProtKB:P11586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000749 ! formate-tetrahydrofolate ligase activity relationship: has_function CCO:F0000875 ! methenyltetrahydrofolate cyclohydrolase activity relationship: has_function CCO:F0000883 ! methylenetetrahydrofolate dehydrogenase activity relationship: has_function CCO:F0000885 ! methylenetetrahydrofolate dehydrogenase (NADP+) activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003046 ! formyltetrahydrofolate dehydrogenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0050859 ! C1TC_HUMAN [Term] id: CCO:B0052307 name: CA149_HUMAN-Phosphoserine136 def: "Protein CA149_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q9HAF1] xref: UniProtKB:Q9HAF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049761 ! CA149_HUMAN [Term] id: CCO:B0052319 name: CCHCR_HUMAN-Phosphoserine88 def: "Protein CCHCR_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q8TD31] xref: UniProtKB:Q8TD31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0050075 ! CCHCR_HUMAN [Term] id: CCO:B0052320 name: CD40L_HUMAN-Phosphothreonine4 def: "Protein CD40L_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:P29965] comment: By similarity xref: UniProtKB:P29965 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001475 ! CD40 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0050340 ! CD40L_HUMAN [Term] id: CCO:B0052321 name: CEAM6_HUMAN-Phosphoserine243 def: "Protein CEAM6_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:P40199] xref: UniProtKB:P40199 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: transformation_of CCO:B0029695 ! CEAM6_HUMAN [Term] id: CCO:B0052322 name: CEBPZ_HUMAN-Phosphoserine231 def: "Protein CEBPZ_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q03701] xref: UniProtKB:Q03701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0024821 ! CEBPZ_HUMAN [Term] id: CCO:B0052323 name: CEBPZ_HUMAN-Phosphoserine232 def: "Protein CEBPZ_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q03701] xref: UniProtKB:Q03701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024821 ! CEBPZ_HUMAN [Term] id: CCO:B0052324 name: CEBPZ_HUMAN-Phosphothreonine233 def: "Protein CEBPZ_HUMAN with the residue 233 substituted with Phosphothreonine" [UniProtKB:Q03701] xref: UniProtKB:Q03701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024821 ! CEBPZ_HUMAN [Term] id: CCO:B0052325 name: CEBPZ_HUMAN-Phosphoserine629 def: "Protein CEBPZ_HUMAN with the residue 629 substituted with Phosphoserine" [UniProtKB:Q03701] xref: UniProtKB:Q03701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024821 ! CEBPZ_HUMAN [Term] id: CCO:B0052326 name: CEBPZ_HUMAN-Phosphoserine835 def: "Protein CEBPZ_HUMAN with the residue 835 substituted with Phosphoserine" [UniProtKB:Q03701] xref: UniProtKB:Q03701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024821 ! CEBPZ_HUMAN [Term] id: CCO:B0052328 name: CHSP1_HUMAN-Phosphoserine146 def: "Protein CHSP1_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q9Y2V2] xref: UniProtKB:Q9Y2V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021340 ! CHSP1_HUMAN [Term] id: CCO:B0052329 name: CHSP1_HUMAN-Phosphoserine147 def: "Protein CHSP1_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:Q9Y2V2] xref: UniProtKB:Q9Y2V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004211 ! phosphatase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0021340 ! CHSP1_HUMAN [Term] id: CCO:B0052342 name: CLPT1_HUMAN-Phosphothreonine213 def: "Protein CLPT1_HUMAN with the residue 213 substituted with Phosphothreonine" [UniProtKB:O96005] xref: UniProtKB:O96005 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051232 ! CLPT1_HUMAN [Term] id: CCO:B0052343 name: CLPT1_HUMAN-Phosphothreonine216 def: "Protein CLPT1_HUMAN with the residue 216 substituted with Phosphothreonine" [UniProtKB:O96005] xref: UniProtKB:O96005 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051232 ! CLPT1_HUMAN [Term] id: CCO:B0052344 name: CNOT2_HUMAN-Phosphoserine101 def: "Protein CNOT2_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q9NZN8] xref: UniProtKB:Q9NZN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0049757 ! CNOT2_HUMAN [Term] id: CCO:B0052345 name: CNOT6_HUMAN-Phosphothreonine146 def: "Protein CNOT6_HUMAN with the residue 146 substituted with Phosphothreonine" [UniProtKB:Q9ULM6] comment: By similarity xref: UniProtKB:Q9ULM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0019074 ! CNOT6_HUMAN [Term] id: CCO:B0052349 name: CXA1_HUMAN-Phosphoserine365 def: "Protein CXA1_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0052350 name: CXA1_HUMAN-Phosphoserine368 def: "Protein CXA1_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0052351 name: CXA1_HUMAN-Phosphoserine369 def: "Protein CXA1_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0052352 name: CXA1_HUMAN-Phosphoserine373 def: "Protein CXA1_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:P17302] comment: By similarity xref: UniProtKB:P17302 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:B0052353 name: DBPA_HUMAN-Phosphoserine34 def: "Protein DBPA_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P16989] xref: UniProtKB:P16989 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049892 ! DBPA_HUMAN [Term] id: CCO:B0052354 name: DBPA_HUMAN-Phosphoserine134 def: "Protein DBPA_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:P16989] xref: UniProtKB:P16989 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049892 ! DBPA_HUMAN [Term] id: CCO:B0052358 name: DLG4_HUMAN-Phosphotyrosine701 def: "Protein DLG4_HUMAN with the residue 701 substituted with Phosphotyrosine" [UniProtKB:P78352] xref: UniProtKB:P78352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:B0052366 name: EHMT2_HUMAN-Phosphoserine140 def: "Protein EHMT2_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q96KQ7] xref: UniProtKB:Q96KQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:B0052367 name: EHMT2_HUMAN-Phosphoserine232 def: "Protein EHMT2_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q96KQ7] xref: UniProtKB:Q96KQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:B0052368 name: EHMT2_HUMAN-Phosphoserine246 def: "Protein EHMT2_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q96KQ7] xref: UniProtKB:Q96KQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:B0052369 name: EHMT2_HUMAN-Phosphothreonine555 def: "Protein EHMT2_HUMAN with the residue 555 substituted with Phosphothreonine" [UniProtKB:Q96KQ7] comment: By similarity xref: UniProtKB:Q96KQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:B0052370 name: EHMT2_HUMAN-Phosphoserine569 def: "Protein EHMT2_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q96KQ7] xref: UniProtKB:Q96KQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:B0052375 name: EPIPL_HUMAN-Phosphoserine2691 def: "Protein EPIPL_HUMAN with the residue 2691 substituted with Phosphoserine" [UniProtKB:P58107] xref: UniProtKB:P58107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:B0052376 name: EPIPL_HUMAN-Phosphoserine4619 def: "Protein EPIPL_HUMAN with the residue 4619 substituted with Phosphoserine" [UniProtKB:P58107] xref: UniProtKB:P58107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:B0052377 name: EPIPL_HUMAN-Phosphoserine4827 def: "Protein EPIPL_HUMAN with the residue 4827 substituted with Phosphoserine" [UniProtKB:P58107] xref: UniProtKB:P58107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:B0052378 name: EPIPL_HUMAN-Phosphoserine4829 def: "Protein EPIPL_HUMAN with the residue 4829 substituted with Phosphoserine" [UniProtKB:P58107] xref: UniProtKB:P58107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:B0052379 name: EPIPL_HUMAN-Phosphothreonine4833 def: "Protein EPIPL_HUMAN with the residue 4833 substituted with Phosphothreonine" [UniProtKB:P58107] xref: UniProtKB:P58107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:B0052384 name: FOXC2_HUMAN-Phosphoserine235 def: "Protein FOXC2_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0052385 name: FOXC2_HUMAN-Phosphoserine281 def: "Protein FOXC2_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0052386 name: FOXK1_HUMAN-Phosphothreonine245 def: "Protein FOXK1_HUMAN with the residue 245 substituted with Phosphothreonine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0052387 name: FOXK1_HUMAN-Phosphothreonine247 def: "Protein FOXK1_HUMAN with the residue 247 substituted with Phosphothreonine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0052388 name: FOXK2_HUMAN-Phosphoserine428 def: "Protein FOXK2_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q01167] xref: UniProtKB:Q01167 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0015238 ! FOXK2_HUMAN [Term] id: CCO:B0052389 name: FOXO3_HUMAN-Phosphothreonine32 def: "Protein FOXO3_HUMAN with the residue 32 substituted with Phosphothreonine" [UniProtKB:O43524] comment: by PKB/AKT1; xref: UniProtKB:O43524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050345 ! FOXO3_HUMAN [Term] id: CCO:B0052390 name: FOXO3_HUMAN-Phosphoserine209 def: "Protein FOXO3_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:O43524] comment: by STK4; xref: UniProtKB:O43524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050345 ! FOXO3_HUMAN [Term] id: CCO:B0052391 name: FOXO3_HUMAN-Phosphoserine253 def: "Protein FOXO3_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:O43524] comment: by PKB/AKT1; xref: UniProtKB:O43524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050345 ! FOXO3_HUMAN [Term] id: CCO:B0052392 name: FOXO3_HUMAN-Phosphoserine315 def: "Protein FOXO3_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:O43524] comment: by SGK; xref: UniProtKB:O43524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050345 ! FOXO3_HUMAN [Term] id: CCO:B0052393 name: FOXO3_HUMAN-Phosphoserine421 def: "Protein FOXO3_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:O43524] xref: UniProtKB:O43524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050345 ! FOXO3_HUMAN [Term] id: CCO:B0052394 name: FOXO3_HUMAN-Phosphothreonine427 def: "Protein FOXO3_HUMAN with the residue 427 substituted with Phosphothreonine" [UniProtKB:O43524] xref: UniProtKB:O43524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0050345 ! FOXO3_HUMAN [Term] id: CCO:B0052399 name: GBRL2_HUMAN-Phosphoserine10 def: "Protein GBRL2_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P60520] xref: UniProtKB:P60520 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000027 ! SNARE binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_function CCO:F0008016 ! GABA receptor binding relationship: has_function CCO:F0008060 ! ATPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000083 ! autophagic vacuole membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0051349 ! GBRL2_HUMAN [Term] id: CCO:B0052400 name: GBRL2_HUMAN-Phosphoserine39 def: "Protein GBRL2_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:P60520] xref: UniProtKB:P60520 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051349 ! GBRL2_HUMAN [Term] id: CCO:B0052401 name: GELS_HUMAN-Phosphotyrosine86 def: "Protein GELS_HUMAN with the residue 86 substituted with Phosphotyrosine" [UniProtKB:P06396] comment: by SRC; in vitro; xref: UniProtKB:P06396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051611 ! GELS_HUMAN [Term] id: CCO:B0052402 name: GELS_HUMAN-Phosphotyrosine409 def: "Protein GELS_HUMAN with the residue 409 substituted with Phosphotyrosine" [UniProtKB:P06396] comment: by SRC; in vitro; xref: UniProtKB:P06396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051611 ! GELS_HUMAN [Term] id: CCO:B0052403 name: GELS_HUMAN-Phosphotyrosine465 def: "Protein GELS_HUMAN with the residue 465 substituted with Phosphotyrosine" [UniProtKB:P06396] comment: by SRC; xref: UniProtKB:P06396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051611 ! GELS_HUMAN [Term] id: CCO:B0052404 name: GELS_HUMAN-Phosphotyrosine603 def: "Protein GELS_HUMAN with the residue 603 substituted with Phosphotyrosine" [UniProtKB:P06396] comment: by SRC; in vitro; xref: UniProtKB:P06396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0051611 ! GELS_HUMAN [Term] id: CCO:B0052405 name: GELS_HUMAN-Phosphotyrosine651 def: "Protein GELS_HUMAN with the residue 651 substituted with Phosphotyrosine" [UniProtKB:P06396] comment: by SRC; in vitro; xref: UniProtKB:P06396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051611 ! GELS_HUMAN [Term] id: CCO:B0052406 name: GNA11_HUMAN-ADP-ribosylarginine183 def: "Protein GNA11_HUMAN with the residue 183 substituted with ADP-ribosylarginine" [UniProtKB:P29992] comment: by cholera toxin; By similarity xref: UniProtKB:P29992 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030251 ! GNA11_HUMAN [Term] id: CCO:B0052407 name: GNA14_HUMAN-ADP-ribosylarginine179 def: "Protein GNA14_HUMAN with the residue 179 substituted with ADP-ribosylarginine" [UniProtKB:O95837] comment: by cholera toxin; By similarity xref: UniProtKB:O95837 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0030261 ! GNA14_HUMAN [Term] id: CCO:B0052408 name: GNAI3_HUMAN-ADP-ribosylarginine178 def: "Protein GNAI3_HUMAN with the residue 178 substituted with ADP-ribosylarginine" [UniProtKB:P08754] comment: by cholera toxin; By similarity xref: UniProtKB:P08754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030269 ! GNAI3_HUMAN [Term] id: CCO:B0052409 name: GNAI3_HUMAN-ADP-ribosylcysteine351 def: "Protein GNAI3_HUMAN with the residue 351 substituted with ADP-ribosylcysteine" [UniProtKB:P08754] comment: by pertussis toxin; By similarity xref: UniProtKB:P08754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030269 ! GNAI3_HUMAN [Term] id: CCO:B0052410 name: GNAO_HUMAN-ADP-ribosylarginine179 def: "Protein GNAO_HUMAN with the residue 179 substituted with ADP-ribosylarginine" [UniProtKB:P09471] comment: by cholera toxin; By similarity xref: UniProtKB:P09471 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049381 ! GNAO_HUMAN [Term] id: CCO:B0052411 name: GNAO_HUMAN-ADP-ribosylcysteine351 def: "Protein GNAO_HUMAN with the residue 351 substituted with ADP-ribosylcysteine" [UniProtKB:P09471] comment: by pertussis toxin; By similarity xref: UniProtKB:P09471 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049381 ! GNAO_HUMAN [Term] id: CCO:B0052413 name: GNAT1_HUMAN-Phosphotyrosine142 def: "Protein GNAT1_HUMAN with the residue 142 substituted with Phosphotyrosine" [UniProtKB:P11488] comment: by SRC; xref: UniProtKB:P11488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030266 ! GNAT1_HUMAN [Term] id: CCO:B0052414 name: GNAT1_HUMAN-ADP-ribosylarginine174 def: "Protein GNAT1_HUMAN with the residue 174 substituted with ADP-ribosylarginine" [UniProtKB:P11488] comment: by cholera toxin; By similarity xref: UniProtKB:P11488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030266 ! GNAT1_HUMAN [Term] id: CCO:B0052415 name: GNAT1_HUMAN-ADP-ribosylcysteine347 def: "Protein GNAT1_HUMAN with the residue 347 substituted with ADP-ribosylcysteine" [UniProtKB:P11488] comment: by pertussis toxin; By similarity xref: UniProtKB:P11488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030266 ! GNAT1_HUMAN [Term] id: CCO:B0052416 name: GNAT2_HUMAN-ADP-ribosylarginine178 def: "Protein GNAT2_HUMAN with the residue 178 substituted with ADP-ribosylarginine" [UniProtKB:P19087] comment: by cholera toxin; By similarity xref: UniProtKB:P19087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030262 ! GNAT2_HUMAN [Term] id: CCO:B0052417 name: GNAT2_HUMAN-ADP-ribosylcysteine351 def: "Protein GNAT2_HUMAN with the residue 351 substituted with ADP-ribosylcysteine" [UniProtKB:P19087] comment: by pertussis toxin; By similarity xref: UniProtKB:P19087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001680 ! G-protein coupled photoreceptor activity relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: transformation_of CCO:B0030262 ! GNAT2_HUMAN [Term] id: CCO:B0052418 name: GNAZ_HUMAN-ADP-ribosylarginine179 def: "Protein GNAZ_HUMAN with the residue 179 substituted with ADP-ribosylarginine" [UniProtKB:P19086] comment: by cholera toxin; By similarity xref: UniProtKB:P19086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030249 ! GNAZ_HUMAN [Term] id: CCO:B0052420 name: HDAC7_HUMAN-Phosphotyrosine114 def: "Protein HDAC7_HUMAN with the residue 114 substituted with Phosphotyrosine" [UniProtKB:Q8WUI4] xref: UniProtKB:Q8WUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002002 ! HDAC7_HUMAN [Term] id: CCO:B0052421 name: HMGB2_HUMAN-Phosphoserine35 def: "Protein HMGB2_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:P26583] xref: UniProtKB:P26583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050294 ! HMGB2_HUMAN [Term] id: CCO:B0052422 name: HMGB2_HUMAN-Phosphotyrosine155 def: "Protein HMGB2_HUMAN with the residue 155 substituted with Phosphotyrosine" [UniProtKB:P26583] xref: UniProtKB:P26583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050294 ! HMGB2_HUMAN [Term] id: CCO:B0052423 name: HMGB2_HUMAN-Phosphotyrosine162 def: "Protein HMGB2_HUMAN with the residue 162 substituted with Phosphotyrosine" [UniProtKB:P26583] xref: UniProtKB:P26583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050294 ! HMGB2_HUMAN [Term] id: CCO:B0052424 name: HSF1_HUMAN-Phosphoserine314 def: "Protein HSF1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:Q00613] xref: UniProtKB:Q00613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:B0052425 name: HSF1_HUMAN-Phosphoserine326 def: "Protein HSF1_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:Q00613] xref: UniProtKB:Q00613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:B0052431 name: IF4B_HUMAN-Phosphoserine93 def: "Protein IF4B_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052432 name: IF4B_HUMAN-Phosphoserine192 def: "Protein IF4B_HUMAN with the residue 192 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052433 name: IF4B_HUMAN-Phosphoserine406 def: "Protein IF4B_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052434 name: IF4B_HUMAN-Phosphoserine422 def: "Protein IF4B_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052435 name: IF4B_HUMAN-Phosphoserine425 def: "Protein IF4B_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052436 name: IF4B_HUMAN-Phosphoserine445 def: "Protein IF4B_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052437 name: IF4B_HUMAN-Phosphoserine459 def: "Protein IF4B_HUMAN with the residue 459 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052438 name: IF4B_HUMAN-Phosphothreonine461 def: "Protein IF4B_HUMAN with the residue 461 substituted with Phosphothreonine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052439 name: IF4B_HUMAN-Phosphoserine495 def: "Protein IF4B_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052440 name: IF4B_HUMAN-Phosphoserine498 def: "Protein IF4B_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052441 name: IF4B_HUMAN-Phosphoserine504 def: "Protein IF4B_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:P23588] xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052442 name: IF4B_HUMAN-Phosphoserine597 def: "Protein IF4B_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:P23588] comment: By similarity xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0052443 name: IF5_HUMAN-Phosphoserine149 def: "Protein IF5_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0052444 name: IF5_HUMAN-Phosphoserine389 def: "Protein IF5_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0052445 name: IF5_HUMAN-Phosphoserine390 def: "Protein IF5_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0052446 name: IF5_HUMAN-Phosphotyrosine405 def: "Protein IF5_HUMAN with the residue 405 substituted with Phosphotyrosine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0052447 name: IF5_HUMAN-Phosphoserine410 def: "Protein IF5_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0052448 name: IKZF3_HUMAN-Phosphotyrosine286 def: "Protein IKZF3_HUMAN with the residue 286 substituted with Phosphotyrosine" [UniProtKB:Q9UKT9] xref: UniProtKB:Q9UKT9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038370 ! IKZF3_HUMAN [Term] id: CCO:B0052449 name: IKZF3_HUMAN-Phosphotyrosine290 def: "Protein IKZF3_HUMAN with the residue 290 substituted with Phosphotyrosine" [UniProtKB:Q9UKT9] xref: UniProtKB:Q9UKT9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038370 ! IKZF3_HUMAN [Term] id: CCO:B0052450 name: IPO5_HUMAN-N-acetylalanine2 def: "Protein IPO5_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O00410] xref: UniProtKB:O00410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050166 ! IPO5_HUMAN [Term] id: CCO:B0052451 name: IPO5_HUMAN-Phosphoserine827 def: "Protein IPO5_HUMAN with the residue 827 substituted with Phosphoserine" [UniProtKB:O00410] xref: UniProtKB:O00410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050166 ! IPO5_HUMAN [Term] id: CCO:B0052452 name: IQGA2_HUMAN-Phosphoserine16 def: "Protein IQGA2_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q13576] xref: UniProtKB:Q13576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018391 ! IQGA2_HUMAN [Term] id: CCO:B0052453 name: IRS1_HUMAN-Phosphoserine3 def: "Protein IRS1_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:P35568] comment: By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052454 name: IRS1_HUMAN-Phosphotyrosine46 def: "Protein IRS1_HUMAN with the residue 46 substituted with Phosphotyrosine" [UniProtKB:P35568] xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052455 name: IRS1_HUMAN-Phosphoserine99 def: "Protein IRS1_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:P35568] comment: by CK2; By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052456 name: IRS1_HUMAN-Phosphoserine312 def: "Protein IRS1_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:P35568] comment: By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052457 name: IRS1_HUMAN-Phosphoserine329 def: "Protein IRS1_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:P35568] comment: By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052458 name: IRS1_HUMAN-Phosphoserine345 def: "Protein IRS1_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:P35568] comment: By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052459 name: IRS1_HUMAN-Phosphotyrosine465 def: "Protein IRS1_HUMAN with the residue 465 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052460 name: IRS1_HUMAN-Phosphoserine531 def: "Protein IRS1_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:P35568] xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052461 name: IRS1_HUMAN-Phosphotyrosine612 def: "Protein IRS1_HUMAN with the residue 612 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052462 name: IRS1_HUMAN-Phosphoserine629 def: "Protein IRS1_HUMAN with the residue 629 substituted with Phosphoserine" [UniProtKB:P35568] xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052463 name: IRS1_HUMAN-Phosphotyrosine632 def: "Protein IRS1_HUMAN with the residue 632 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001379 ! transmembrane receptor protein tyrosine kinase docking protein activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0005873 ! phosphoinositide 3-kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052464 name: IRS1_HUMAN-Phosphoserine636 def: "Protein IRS1_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:P35568] xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052465 name: IRS1_HUMAN-Phosphotyrosine662 def: "Protein IRS1_HUMAN with the residue 662 substituted with Phosphotyrosine" [UniProtKB:P35568] xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052466 name: IRS1_HUMAN-Phosphoserine794 def: "Protein IRS1_HUMAN with the residue 794 substituted with Phosphoserine" [UniProtKB:P35568] comment: by SNF1LK2; xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052467 name: IRS1_HUMAN-Phosphotyrosine896 def: "Protein IRS1_HUMAN with the residue 896 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052468 name: IRS1_HUMAN-Phosphotyrosine941 def: "Protein IRS1_HUMAN with the residue 941 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052469 name: IRS1_HUMAN-Phosphotyrosine989 def: "Protein IRS1_HUMAN with the residue 989 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052470 name: IRS1_HUMAN-Phosphoserine1101 def: "Protein IRS1_HUMAN with the residue 1101 substituted with Phosphoserine" [UniProtKB:P35568] xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052471 name: IRS1_HUMAN-Phosphoserine1145 def: "Protein IRS1_HUMAN with the residue 1145 substituted with Phosphoserine" [UniProtKB:P35568] comment: By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052472 name: IRS1_HUMAN-Phosphotyrosine1179 def: "Protein IRS1_HUMAN with the residue 1179 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052473 name: IRS1_HUMAN-Phosphoserine1223 def: "Protein IRS1_HUMAN with the residue 1223 substituted with Phosphoserine" [UniProtKB:P35568] comment: By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052474 name: IRS1_HUMAN-Phosphotyrosine1229 def: "Protein IRS1_HUMAN with the residue 1229 substituted with Phosphotyrosine" [UniProtKB:P35568] comment: by INSR; By similarity xref: UniProtKB:P35568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:B0052500 name: IRS4_HUMAN-Phosphotyrosine921 def: "Protein IRS4_HUMAN with the residue 921 substituted with Phosphotyrosine" [UniProtKB:O14654] xref: UniProtKB:O14654 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0051815 ! IRS4_HUMAN [Term] id: CCO:B0052502 name: ITA2_HUMAN-Phosphothreonine1177 def: "Protein ITA2_HUMAN with the residue 1177 substituted with Phosphothreonine" [UniProtKB:P17301] xref: UniProtKB:P17301 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050196 ! ITA2_HUMAN [Term] id: CCO:B0052505 name: KC1D_HUMAN-Phosphoserine383 def: "Protein KC1D_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:P48730] xref: UniProtKB:P48730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017481 ! KC1D_HUMAN [Term] id: CCO:B0052517 name: LIPA1_HUMAN-Phosphotyrosine684 def: "Protein LIPA1_HUMAN with the residue 684 substituted with Phosphotyrosine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0052518 name: LIPA1_HUMAN-Phosphoserine763 def: "Protein LIPA1_HUMAN with the residue 763 substituted with Phosphoserine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0052533 name: MAP2_HUMAN-Phosphoserine63 def: "Protein MAP2_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:P11137] xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052534 name: MAP2_HUMAN-Phosphoserine610 def: "Protein MAP2_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052535 name: MAP2_HUMAN-Phosphoserine629 def: "Protein MAP2_HUMAN with the residue 629 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052536 name: MAP2_HUMAN-Phosphoserine654 def: "Protein MAP2_HUMAN with the residue 654 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052537 name: MAP2_HUMAN-Phosphoserine729 def: "Protein MAP2_HUMAN with the residue 729 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052538 name: MAP2_HUMAN-Phosphoserine736 def: "Protein MAP2_HUMAN with the residue 736 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052539 name: MAP2_HUMAN-Phosphotyrosine745 def: "Protein MAP2_HUMAN with the residue 745 substituted with Phosphotyrosine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052540 name: MAP2_HUMAN-Phosphoserine821 def: "Protein MAP2_HUMAN with the residue 821 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052541 name: MAP2_HUMAN-Phosphoserine833 def: "Protein MAP2_HUMAN with the residue 833 substituted with Phosphoserine" [UniProtKB:P11137] xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052542 name: MAP2_HUMAN-Phosphoserine1155 def: "Protein MAP2_HUMAN with the residue 1155 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052543 name: MAP2_HUMAN-Phosphoserine1347 def: "Protein MAP2_HUMAN with the residue 1347 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052544 name: MAP2_HUMAN-Phosphoserine1353 def: "Protein MAP2_HUMAN with the residue 1353 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052545 name: MAP2_HUMAN-Phosphoserine1421 def: "Protein MAP2_HUMAN with the residue 1421 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052546 name: MAP2_HUMAN-Phosphothreonine1440 def: "Protein MAP2_HUMAN with the residue 1440 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052547 name: MAP2_HUMAN-Phosphoserine1480 def: "Protein MAP2_HUMAN with the residue 1480 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052548 name: MAP2_HUMAN-Phosphoserine1534 def: "Protein MAP2_HUMAN with the residue 1534 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052549 name: MAP2_HUMAN-Phosphoserine1591 def: "Protein MAP2_HUMAN with the residue 1591 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052550 name: MAP2_HUMAN-Phosphothreonine1594 def: "Protein MAP2_HUMAN with the residue 1594 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052551 name: MAP2_HUMAN-Phosphothreonine1595 def: "Protein MAP2_HUMAN with the residue 1595 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052552 name: MAP2_HUMAN-Phosphothreonine1602 def: "Protein MAP2_HUMAN with the residue 1602 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052553 name: MAP2_HUMAN-Phosphothreonine1605 def: "Protein MAP2_HUMAN with the residue 1605 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052554 name: MAP2_HUMAN-Phosphoserine1608 def: "Protein MAP2_HUMAN with the residue 1608 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052555 name: MAP2_HUMAN-Phosphoserine1611 def: "Protein MAP2_HUMAN with the residue 1611 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052556 name: MAP2_HUMAN-Phosphothreonine1613 def: "Protein MAP2_HUMAN with the residue 1613 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052557 name: MAP2_HUMAN-Phosphothreonine1616 def: "Protein MAP2_HUMAN with the residue 1616 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052558 name: MAP2_HUMAN-Phosphothreonine1649 def: "Protein MAP2_HUMAN with the residue 1649 substituted with Phosphothreonine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052559 name: MAP2_HUMAN-Phosphoserine1782 def: "Protein MAP2_HUMAN with the residue 1782 substituted with Phosphoserine" [UniProtKB:P11137] xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052560 name: MAP2_HUMAN-Phosphoserine1790 def: "Protein MAP2_HUMAN with the residue 1790 substituted with Phosphoserine" [UniProtKB:P11137] comment: By similarity xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052561 name: MAP2_HUMAN-Phosphoserine1798 def: "Protein MAP2_HUMAN with the residue 1798 substituted with Phosphoserine" [UniProtKB:P11137] xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052562 name: MAP2_HUMAN-Phosphoserine1799 def: "Protein MAP2_HUMAN with the residue 1799 substituted with Phosphoserine" [UniProtKB:P11137] xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052563 name: MAP2_HUMAN-Phosphoserine1800 def: "Protein MAP2_HUMAN with the residue 1800 substituted with Phosphoserine" [UniProtKB:P11137] xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052564 name: MAP2_HUMAN-Phosphoserine1802 def: "Protein MAP2_HUMAN with the residue 1802 substituted with Phosphoserine" [UniProtKB:P11137] xref: UniProtKB:P11137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050955 ! MAP2_HUMAN [Term] id: CCO:B0052579 name: MLL2_HUMAN-Phosphoserine1545 def: "Protein MLL2_HUMAN with the residue 1545 substituted with Phosphoserine" [UniProtKB:O14686] xref: UniProtKB:O14686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:B0052580 name: MLL2_HUMAN-Phosphoserine2855 def: "Protein MLL2_HUMAN with the residue 2855 substituted with Phosphoserine" [UniProtKB:O14686] xref: UniProtKB:O14686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:B0052581 name: MLL2_HUMAN-Phosphoserine4463 def: "Protein MLL2_HUMAN with the residue 4463 substituted with Phosphoserine" [UniProtKB:O14686] xref: UniProtKB:O14686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:B0052582 name: MLL3_HUMAN-N6-acetyllysine2809 def: "Protein MLL3_HUMAN with the residue 2809 substituted with N6-acetyllysine" [UniProtKB:Q8NEZ4] xref: UniProtKB:Q8NEZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050358 ! MLL3_HUMAN [Term] id: CCO:B0052583 name: MLL3_HUMAN-Phosphotyrosine4018 def: "Protein MLL3_HUMAN with the residue 4018 substituted with Phosphotyrosine" [UniProtKB:Q8NEZ4] xref: UniProtKB:Q8NEZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050358 ! MLL3_HUMAN [Term] id: CCO:B0052584 name: MLL3_HUMAN-Phosphoserine4022 def: "Protein MLL3_HUMAN with the residue 4022 substituted with Phosphoserine" [UniProtKB:Q8NEZ4] xref: UniProtKB:Q8NEZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050358 ! MLL3_HUMAN [Term] id: CCO:B0052585 name: MLL3_HUMAN-Phosphoserine4034 def: "Protein MLL3_HUMAN with the residue 4034 substituted with Phosphoserine" [UniProtKB:Q8NEZ4] xref: UniProtKB:Q8NEZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0050358 ! MLL3_HUMAN [Term] id: CCO:B0052586 name: MLL3_HUMAN-Phosphoserine4050 def: "Protein MLL3_HUMAN with the residue 4050 substituted with Phosphoserine" [UniProtKB:Q8NEZ4] xref: UniProtKB:Q8NEZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050358 ! MLL3_HUMAN [Term] id: CCO:B0052596 name: MP2K5_HUMAN-Phosphoserine311 def: "Protein MP2K5_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q13163] xref: UniProtKB:Q13163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050242 ! MP2K5_HUMAN [Term] id: CCO:B0052597 name: MP2K5_HUMAN-Phosphothreonine315 def: "Protein MP2K5_HUMAN with the residue 315 substituted with Phosphothreonine" [UniProtKB:Q13163] xref: UniProtKB:Q13163 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050242 ! MP2K5_HUMAN [Term] id: CCO:B0052598 name: MTSSL_HUMAN-Phosphoserine300 def: "Protein MTSSL_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0052599 name: MTSSL_HUMAN-Phosphoserine388 def: "Protein MTSSL_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0052600 name: MTSSL_HUMAN-Phosphoserine601 def: "Protein MTSSL_HUMAN with the residue 601 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0052601 name: MTSSL_HUMAN-Phosphoserine639 def: "Protein MTSSL_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0052602 name: MTSSL_HUMAN-Phosphothreonine643 def: "Protein MTSSL_HUMAN with the residue 643 substituted with Phosphothreonine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0052603 name: MTSSL_HUMAN-Phosphoserine647 def: "Protein MTSSL_HUMAN with the residue 647 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0052607 name: MYST3_HUMAN-Phosphoserine941 def: "Protein MYST3_HUMAN with the residue 941 substituted with Phosphoserine" [UniProtKB:Q92794] xref: UniProtKB:Q92794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:B0052608 name: MYST4_HUMAN-Phosphoserine1048 def: "Protein MYST4_HUMAN with the residue 1048 substituted with Phosphoserine" [UniProtKB:Q8WYB5] xref: UniProtKB:Q8WYB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017931 ! MYST4_HUMAN [Term] id: CCO:B0052610 name: NLE1_HUMAN-N-acetylalanine2 def: "Protein NLE1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9NVX2] xref: UniProtKB:Q9NVX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0050490 ! NLE1_HUMAN [Term] id: CCO:B0052611 name: NLE1_HUMAN-Phosphoserine79 def: "Protein NLE1_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q9NVX2] xref: UniProtKB:Q9NVX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050490 ! NLE1_HUMAN [Term] id: CCO:B0052616 name: PDLI4_HUMAN-Phosphoserine112 def: "Protein PDLI4_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:P50479] comment: By similarity xref: UniProtKB:P50479 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017106 ! PDLI4_HUMAN [Term] id: CCO:B0052617 name: PDLI4_HUMAN-Phosphoserine120 def: "Protein PDLI4_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P50479] comment: By similarity xref: UniProtKB:P50479 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017106 ! PDLI4_HUMAN [Term] id: CCO:B0052621 name: PGRC1_HUMAN-Phosphoserine57 def: "Protein PGRC1_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:O00264] xref: UniProtKB:O00264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051023 ! PGRC1_HUMAN [Term] id: CCO:B0052622 name: PGRC1_HUMAN-Phosphothreonine178 def: "Protein PGRC1_HUMAN with the residue 178 substituted with Phosphothreonine" [UniProtKB:O00264] comment: By similarity xref: UniProtKB:O00264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051023 ! PGRC1_HUMAN [Term] id: CCO:B0052623 name: PGRC1_HUMAN-Phosphotyrosine180 def: "Protein PGRC1_HUMAN with the residue 180 substituted with Phosphotyrosine" [UniProtKB:O00264] xref: UniProtKB:O00264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051023 ! PGRC1_HUMAN [Term] id: CCO:B0052624 name: PGRC1_HUMAN-Phosphoserine181 def: "Protein PGRC1_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:O00264] xref: UniProtKB:O00264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0051023 ! PGRC1_HUMAN [Term] id: CCO:B0052634 name: PLEC1_HUMAN-Phosphoserine125 def: "Protein PLEC1_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052635 name: PLEC1_HUMAN-Phosphoserine149 def: "Protein PLEC1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052636 name: PLEC1_HUMAN-Phosphoserine720 def: "Protein PLEC1_HUMAN with the residue 720 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052637 name: PLEC1_HUMAN-Phosphoserine782 def: "Protein PLEC1_HUMAN with the residue 782 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052638 name: PLEC1_HUMAN-Phosphoserine1435 def: "Protein PLEC1_HUMAN with the residue 1435 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052639 name: PLEC1_HUMAN-Phosphoserine1644 def: "Protein PLEC1_HUMAN with the residue 1644 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052640 name: PLEC1_HUMAN-Phosphoserine1721 def: "Protein PLEC1_HUMAN with the residue 1721 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052641 name: PLEC1_HUMAN-Phosphoserine2755 def: "Protein PLEC1_HUMAN with the residue 2755 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052642 name: PLEC1_HUMAN-Phosphothreonine2814 def: "Protein PLEC1_HUMAN with the residue 2814 substituted with Phosphothreonine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052643 name: PLEC1_HUMAN-Phosphotyrosine3033 def: "Protein PLEC1_HUMAN with the residue 3033 substituted with Phosphotyrosine" [UniProtKB:Q15149] comment: By similarity xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052644 name: PLEC1_HUMAN-Phosphotyrosine3362 def: "Protein PLEC1_HUMAN with the residue 3362 substituted with Phosphotyrosine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052645 name: PLEC1_HUMAN-Phosphothreonine4030 def: "Protein PLEC1_HUMAN with the residue 4030 substituted with Phosphothreonine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052646 name: PLEC1_HUMAN-Phosphoserine4382 def: "Protein PLEC1_HUMAN with the residue 4382 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052647 name: PLEC1_HUMAN-Phosphoserine4384 def: "Protein PLEC1_HUMAN with the residue 4384 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052648 name: PLEC1_HUMAN-Phosphoserine4385 def: "Protein PLEC1_HUMAN with the residue 4385 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052649 name: PLEC1_HUMAN-Phosphoserine4386 def: "Protein PLEC1_HUMAN with the residue 4386 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052650 name: PLEC1_HUMAN-Phosphoserine4389 def: "Protein PLEC1_HUMAN with the residue 4389 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052651 name: PLEC1_HUMAN-Phosphoserine4390 def: "Protein PLEC1_HUMAN with the residue 4390 substituted with Phosphoserine" [UniProtKB:Q15149] comment: By similarity xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052652 name: PLEC1_HUMAN-Phosphoserine4391 def: "Protein PLEC1_HUMAN with the residue 4391 substituted with Phosphoserine" [UniProtKB:Q15149] comment: By similarity xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052653 name: PLEC1_HUMAN-Phosphoserine4396 def: "Protein PLEC1_HUMAN with the residue 4396 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052654 name: PLEC1_HUMAN-Phosphothreonine4402 def: "Protein PLEC1_HUMAN with the residue 4402 substituted with Phosphothreonine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052655 name: PLEC1_HUMAN-Phosphothreonine4411 def: "Protein PLEC1_HUMAN with the residue 4411 substituted with Phosphothreonine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052656 name: PLEC1_HUMAN-Phosphothreonine4539 def: "Protein PLEC1_HUMAN with the residue 4539 substituted with Phosphothreonine" [UniProtKB:Q15149] comment: by CDC2; By similarity xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052657 name: PLEC1_HUMAN-Phosphotyrosine4611 def: "Protein PLEC1_HUMAN with the residue 4611 substituted with Phosphotyrosine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052658 name: PLEC1_HUMAN-Phosphoserine4613 def: "Protein PLEC1_HUMAN with the residue 4613 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052659 name: PLEC1_HUMAN-Phosphotyrosine4615 def: "Protein PLEC1_HUMAN with the residue 4615 substituted with Phosphotyrosine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052660 name: PLEC1_HUMAN-Phosphoserine4620 def: "Protein PLEC1_HUMAN with the residue 4620 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052661 name: PLEC1_HUMAN-Phosphoserine4622 def: "Protein PLEC1_HUMAN with the residue 4622 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052662 name: PLEC1_HUMAN-Phosphothreonine4623 def: "Protein PLEC1_HUMAN with the residue 4623 substituted with Phosphothreonine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052663 name: PLEC1_HUMAN-Phosphoserine4626 def: "Protein PLEC1_HUMAN with the residue 4626 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0052668 name: PURB_HUMAN-Phosphoserine101 def: "Protein PURB_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q96QR8] xref: UniProtKB:Q96QR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:B0052677 name: PYRG2_HUMAN-Phosphoserine568 def: "Protein PYRG2_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:Q9NRF8] xref: UniProtKB:Q9NRF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049297 ! PYRG2_HUMAN [Term] id: CCO:B0052678 name: PYRG2_HUMAN-Phosphoserine571 def: "Protein PYRG2_HUMAN with the residue 571 substituted with Phosphoserine" [UniProtKB:Q9NRF8] xref: UniProtKB:Q9NRF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049297 ! PYRG2_HUMAN [Term] id: CCO:B0052679 name: PYRG2_HUMAN-Phosphoserine574 def: "Protein PYRG2_HUMAN with the residue 574 substituted with Phosphoserine" [UniProtKB:Q9NRF8] xref: UniProtKB:Q9NRF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000402 ! CTP synthase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049297 ! PYRG2_HUMAN [Term] id: CCO:B0052686 name: RGPS2_HUMAN-Phosphoserine422 def: "Protein RGPS2_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q86X27] xref: UniProtKB:Q86X27 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037994 ! RGPS2_HUMAN [Term] id: CCO:B0052687 name: RICTR_HUMAN-Phosphoserine21 def: "Protein RICTR_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q6R327] xref: UniProtKB:Q6R327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048930 ! RICTR_HUMAN [Term] id: CCO:B0052688 name: RICTR_HUMAN-Phosphothreonine1295 def: "Protein RICTR_HUMAN with the residue 1295 substituted with Phosphothreonine" [UniProtKB:Q6R327] xref: UniProtKB:Q6R327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048930 ! RICTR_HUMAN [Term] id: CCO:B0052689 name: RING1_HUMAN-Phosphoserine38 def: "Protein RING1_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:Q06587] xref: UniProtKB:Q06587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020553 ! RING1_HUMAN [Term] id: CCO:B0052693 name: RNF4_HUMAN-Phosphoserine94 def: "Protein RNF4_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:P78317] xref: UniProtKB:P78317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049848 ! RNF4_HUMAN [Term] id: CCO:B0052694 name: RNF4_HUMAN-Phosphoserine95 def: "Protein RNF4_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:P78317] xref: UniProtKB:P78317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049848 ! RNF4_HUMAN [Term] id: CCO:B0052695 name: ROA0_HUMAN-Phosphoserine84 def: "Protein ROA0_HUMAN with the residue 84 substituted with Phosphoserine" [UniProtKB:Q13151] xref: UniProtKB:Q13151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0028238 ! ROA0_HUMAN [Term] id: CCO:B0052696 name: ROA0_HUMAN-Phosphotyrosine180 def: "Protein ROA0_HUMAN with the residue 180 substituted with Phosphotyrosine" [UniProtKB:Q13151] xref: UniProtKB:Q13151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028238 ! ROA0_HUMAN [Term] id: CCO:B0052697 name: ROA0_HUMAN-Omega-N-methylated arginine291 def: "Protein ROA0_HUMAN with the residue 291 substituted with Omega-N-methylated arginine" [UniProtKB:Q13151] xref: UniProtKB:Q13151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028238 ! ROA0_HUMAN [Term] id: CCO:B0052698 name: ROA3_HUMAN-Phosphoserine116 def: "Protein ROA3_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:P51991] xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0052699 name: ROA3_HUMAN-Phosphoserine355 def: "Protein ROA3_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:P51991] xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0052700 name: ROA3_HUMAN-Phosphoserine356 def: "Protein ROA3_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:P51991] xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0052701 name: ROA3_HUMAN-Phosphoserine358 def: "Protein ROA3_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:P51991] xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0052702 name: ROA3_HUMAN-Phosphotyrosine360 def: "Protein ROA3_HUMAN with the residue 360 substituted with Phosphotyrosine" [UniProtKB:P51991] xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0052703 name: ROA3_HUMAN-Phosphoserine370 def: "Protein ROA3_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:P51991] comment: By similarity xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0052704 name: ROA3_HUMAN-Phosphoserine375 def: "Protein ROA3_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:P51991] comment: By similarity xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0052705 name: ROS_HUMAN-Phosphotyrosine2114 def: "Protein ROS_HUMAN with the residue 2114 substituted with Phosphotyrosine" [UniProtKB:P08922] comment: by autocatalysis; By similarity xref: UniProtKB:P08922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000447 ! sodium:potassium-exchanging ATPase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0029082 ! ROS_HUMAN [Term] id: CCO:B0052706 name: RP1BL_HUMAN-ADP-ribosylserine39 def: "Protein RP1BL_HUMAN with the residue 39 substituted with ADP-ribosylserine" [UniProtKB:A6NIZ1] comment: by botulinum toxin; By similarity xref: UniProtKB:A6NIZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051199 ! RP1BL_HUMAN [Term] id: CCO:B0052707 name: RP1BL_HUMAN-Phosphoserine179 def: "Protein RP1BL_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:A6NIZ1] comment: by PKA; By similarity xref: UniProtKB:A6NIZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051199 ! RP1BL_HUMAN [Term] id: CCO:B0052708 name: RP1BL_HUMAN-Cysteine methyl ester181 def: "Protein RP1BL_HUMAN with the residue 181 substituted with Cysteine methyl ester" [UniProtKB:A6NIZ1] comment: By similarity xref: UniProtKB:A6NIZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051199 ! RP1BL_HUMAN [Term] id: CCO:B0052711 name: RTF1_HUMAN-Phosphoserine657 def: "Protein RTF1_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:Q92541] xref: UniProtKB:Q92541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0051565 ! RTF1_HUMAN [Term] id: CCO:B0052719 name: S10A7_HUMAN-N-acetylserine2 def: "Protein S10A7_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P31151] xref: UniProtKB:P31151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000477 ! focal adhesion relationship: transformation_of CCO:B0051700 ! S10A7_HUMAN [Term] id: CCO:B0052728 name: SETD2_HUMAN-Phosphoserine321 def: "Protein SETD2_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0052729 name: SETD2_HUMAN-Phosphoserine323 def: "Protein SETD2_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0052730 name: SETD2_HUMAN-Phosphoserine532 def: "Protein SETD2_HUMAN with the residue 532 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0052731 name: SETD2_HUMAN-Phosphoserine1228 def: "Protein SETD2_HUMAN with the residue 1228 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0052732 name: SETD2_HUMAN-Phosphoserine1413 def: "Protein SETD2_HUMAN with the residue 1413 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0052733 name: SF3B1_HUMAN-Phosphothreonine142 def: "Protein SF3B1_HUMAN with the residue 142 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052734 name: SF3B1_HUMAN-Phosphothreonine207 def: "Protein SF3B1_HUMAN with the residue 207 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052735 name: SF3B1_HUMAN-Phosphothreonine211 def: "Protein SF3B1_HUMAN with the residue 211 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052736 name: SF3B1_HUMAN-Phosphothreonine223 def: "Protein SF3B1_HUMAN with the residue 223 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052737 name: SF3B1_HUMAN-Phosphothreonine227 def: "Protein SF3B1_HUMAN with the residue 227 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052738 name: SF3B1_HUMAN-Phosphothreonine235 def: "Protein SF3B1_HUMAN with the residue 235 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052739 name: SF3B1_HUMAN-Phosphothreonine244 def: "Protein SF3B1_HUMAN with the residue 244 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052740 name: SF3B1_HUMAN-Phosphothreonine248 def: "Protein SF3B1_HUMAN with the residue 248 substituted with Phosphothreonine" [UniProtKB:O75533] comment: Probable xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052741 name: SF3B1_HUMAN-Phosphothreonine257 def: "Protein SF3B1_HUMAN with the residue 257 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052742 name: SF3B1_HUMAN-Phosphothreonine261 def: "Protein SF3B1_HUMAN with the residue 261 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052743 name: SF3B1_HUMAN-Phosphothreonine267 def: "Protein SF3B1_HUMAN with the residue 267 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052744 name: SF3B1_HUMAN-Phosphothreonine296 def: "Protein SF3B1_HUMAN with the residue 296 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052745 name: SF3B1_HUMAN-Phosphothreonine299 def: "Protein SF3B1_HUMAN with the residue 299 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052746 name: SF3B1_HUMAN-Phosphothreonine313 def: "Protein SF3B1_HUMAN with the residue 313 substituted with Phosphothreonine" [UniProtKB:O75533] comment: Probable xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052747 name: SF3B1_HUMAN-Phosphothreonine316 def: "Protein SF3B1_HUMAN with the residue 316 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052748 name: SF3B1_HUMAN-Phosphothreonine326 def: "Protein SF3B1_HUMAN with the residue 326 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052749 name: SF3B1_HUMAN-Phosphothreonine328 def: "Protein SF3B1_HUMAN with the residue 328 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052750 name: SF3B1_HUMAN-Phosphoserine344 def: "Protein SF3B1_HUMAN with the residue 344 substituted with Phosphoserine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052751 name: SF3B1_HUMAN-Phosphothreonine350 def: "Protein SF3B1_HUMAN with the residue 350 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052752 name: SF3B1_HUMAN-Phosphothreonine354 def: "Protein SF3B1_HUMAN with the residue 354 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052753 name: SF3B1_HUMAN-Phosphothreonine432 def: "Protein SF3B1_HUMAN with the residue 432 substituted with Phosphothreonine" [UniProtKB:O75533] xref: UniProtKB:O75533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049991 ! SF3B1_HUMAN [Term] id: CCO:B0052754 name: SFRS3_HUMAN-Phosphoserine81 def: "Protein SFRS3_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052755 name: SFRS3_HUMAN-Phosphoserine95 def: "Protein SFRS3_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052756 name: SFRS3_HUMAN-Phosphoserine108 def: "Protein SFRS3_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052757 name: SFRS3_HUMAN-Phosphoserine138 def: "Protein SFRS3_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052758 name: SFRS3_HUMAN-Phosphoserine140 def: "Protein SFRS3_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052759 name: SFRS3_HUMAN-Phosphoserine148 def: "Protein SFRS3_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052760 name: SFRS3_HUMAN-Phosphoserine150 def: "Protein SFRS3_HUMAN with the residue 150 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052761 name: SFRS3_HUMAN-Phosphoserine152 def: "Protein SFRS3_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:P84103] xref: UniProtKB:P84103 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0050254 ! SFRS3_HUMAN [Term] id: CCO:B0052777 name: SI1L2_HUMAN-Phosphoserine148 def: "Protein SI1L2_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q9P2F8] xref: UniProtKB:Q9P2F8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023489 ! SI1L2_HUMAN [Term] id: CCO:B0052778 name: SI1L2_HUMAN-Phosphoserine1478 def: "Protein SI1L2_HUMAN with the residue 1478 substituted with Phosphoserine" [UniProtKB:Q9P2F8] xref: UniProtKB:Q9P2F8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023489 ! SI1L2_HUMAN [Term] id: CCO:B0052782 name: SNW1_HUMAN-Phosphoserine224 def: "Protein SNW1_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:Q13573] xref: UniProtKB:Q13573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:B0052783 name: SNW1_HUMAN-Phosphoserine232 def: "Protein SNW1_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q13573] xref: UniProtKB:Q13573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:B0052784 name: SNW1_HUMAN-Phosphoserine234 def: "Protein SNW1_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q13573] xref: UniProtKB:Q13573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:B0052786 name: SRBP1_HUMAN-Phosphotyrosine110 def: "Protein SRBP1_HUMAN with the residue 110 substituted with Phosphotyrosine" [UniProtKB:P36956] comment: By similarity xref: UniProtKB:P36956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049929 ! SRBP1_HUMAN [Term] id: CCO:B0052787 name: SRBP1_HUMAN-Phosphoserine1019 def: "Protein SRBP1_HUMAN with the residue 1019 substituted with Phosphoserine" [UniProtKB:P36956] xref: UniProtKB:P36956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049929 ! SRBP1_HUMAN [Term] id: CCO:B0052788 name: SRBP1_HUMAN-Phosphoserine1020 def: "Protein SRBP1_HUMAN with the residue 1020 substituted with Phosphoserine" [UniProtKB:P36956] xref: UniProtKB:P36956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049929 ! SRBP1_HUMAN [Term] id: CCO:B0052789 name: SRBP2_HUMAN-Phosphotyrosine840 def: "Protein SRBP2_HUMAN with the residue 840 substituted with Phosphotyrosine" [UniProtKB:Q12772] xref: UniProtKB:Q12772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0049934 ! SRBP2_HUMAN [Term] id: CCO:B0052790 name: SRBP2_HUMAN-Phosphoserine1121 def: "Protein SRBP2_HUMAN with the residue 1121 substituted with Phosphoserine" [UniProtKB:Q12772] comment: By similarity xref: UniProtKB:Q12772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049934 ! SRBP2_HUMAN [Term] id: CCO:B0052791 name: SSR3_HUMAN-Phosphoserine332 def: "Protein SSR3_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:P32745] comment: By similarity xref: UniProtKB:P32745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050794 ! SSR3_HUMAN [Term] id: CCO:B0052792 name: SSR3_HUMAN-Phosphoserine337 def: "Protein SSR3_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:P32745] comment: By similarity xref: UniProtKB:P32745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050794 ! SSR3_HUMAN [Term] id: CCO:B0052793 name: SSR3_HUMAN-Phosphothreonine348 def: "Protein SSR3_HUMAN with the residue 348 substituted with Phosphothreonine" [UniProtKB:P32745] comment: By similarity xref: UniProtKB:P32745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050794 ! SSR3_HUMAN [Term] id: CCO:B0052794 name: SSR5_HUMAN-Phosphoserine325 def: "Protein SSR5_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:P35346] comment: by PKA; Potential xref: UniProtKB:P35346 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001332 ! somatostatin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0050785 ! SSR5_HUMAN [Term] id: CCO:B0052814 name: TB182_HUMAN-Phosphoserine1024 def: "Protein TB182_HUMAN with the residue 1024 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0052815 name: TB182_HUMAN-Phosphoserine1029 def: "Protein TB182_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0052816 name: TCP4_HUMAN-Phosphoserine9 def: "Protein TCP4_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052817 name: TCP4_HUMAN-Phosphoserine10 def: "Protein TCP4_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052818 name: TCP4_HUMAN-Phosphoserine11 def: "Protein TCP4_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052819 name: TCP4_HUMAN-Phosphoserine12 def: "Protein TCP4_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052820 name: TCP4_HUMAN-Phosphoserine13 def: "Protein TCP4_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052821 name: TCP4_HUMAN-Phosphoserine15 def: "Protein TCP4_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052822 name: TCP4_HUMAN-Phosphoserine17 def: "Protein TCP4_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052823 name: TCP4_HUMAN-Phosphoserine19 def: "Protein TCP4_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052824 name: TCP4_HUMAN-Phosphoserine50 def: "Protein TCP4_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052825 name: TCP4_HUMAN-Phosphoserine52 def: "Protein TCP4_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052826 name: TCP4_HUMAN-Phosphoserine56 def: "Protein TCP4_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052827 name: TCP4_HUMAN-Phosphoserine58 def: "Protein TCP4_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0052828 name: TENA_HUMAN-Phosphoserine72 def: "Protein TENA_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:P24821] comment: By similarity xref: UniProtKB:P24821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050218 ! TENA_HUMAN [Term] id: CCO:B0052829 name: TF3B_HUMAN-Phosphoserine433 def: "Protein TF3B_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:Q92994] xref: UniProtKB:Q92994 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000297 ! RNA polymerase III transcription factor activity relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000014 ! transcription factor TFIIIB complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: transformation_of CCO:B0050546 ! TF3B_HUMAN [Term] id: CCO:B0052830 name: TF3B_HUMAN-Phosphoserine553 def: "Protein TF3B_HUMAN with the residue 553 substituted with Phosphoserine" [UniProtKB:Q92994] xref: UniProtKB:Q92994 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050546 ! TF3B_HUMAN [Term] id: CCO:B0052831 name: TFE3_HUMAN-Phosphoserine568 def: "Protein TFE3_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:P19532] comment: By similarity xref: UniProtKB:P19532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049262 ! TFE3_HUMAN [Term] id: CCO:B0052832 name: TFEB_HUMAN-Phosphoserine467 def: "Protein TFEB_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:P19484] comment: By similarity xref: UniProtKB:P19484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049260 ! TFEB_HUMAN [Term] id: CCO:B0052833 name: TGM2_HUMAN-N-acetylalanine2 def: "Protein TGM2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P21980] comment: By similarity xref: UniProtKB:P21980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000335 ! protein-glutamine gamma-glutamyltransferase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0048975 ! TGM2_HUMAN [Term] id: CCO:B0052834 name: TGM2_HUMAN-Phosphotyrosine369 def: "Protein TGM2_HUMAN with the residue 369 substituted with Phosphotyrosine" [UniProtKB:P21980] xref: UniProtKB:P21980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048975 ! TGM2_HUMAN [Term] id: CCO:B0052835 name: TGM2_HUMAN-Phosphoserine427 def: "Protein TGM2_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:P21980] xref: UniProtKB:P21980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048975 ! TGM2_HUMAN [Term] id: CCO:B0052848 name: TMCC2_HUMAN-Phosphoserine464 def: "Protein TMCC2_HUMAN with the residue 464 substituted with Phosphoserine" [UniProtKB:O75069] comment: By similarity xref: UniProtKB:O75069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051710 ! TMCC2_HUMAN [Term] id: CCO:B0052849 name: TMCC2_HUMAN-Phosphothreonine466 def: "Protein TMCC2_HUMAN with the residue 466 substituted with Phosphothreonine" [UniProtKB:O75069] comment: By similarity xref: UniProtKB:O75069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051710 ! TMCC2_HUMAN [Term] id: CCO:B0052850 name: TMCC2_HUMAN-Phosphoserine470 def: "Protein TMCC2_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:O75069] comment: By similarity xref: UniProtKB:O75069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051710 ! TMCC2_HUMAN [Term] id: CCO:B0052851 name: TMCC2_HUMAN-Phosphoserine481 def: "Protein TMCC2_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:O75069] comment: By similarity xref: UniProtKB:O75069 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0051710 ! TMCC2_HUMAN [Term] id: CCO:B0052853 name: TMSL1_HUMAN-N-acetylserine2 def: "Protein TMSL1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q08EQ4] comment: By similarity xref: UniProtKB:Q08EQ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049174 ! TMSL1_HUMAN [Term] id: CCO:B0052854 name: TMSL2_HUMAN-N-acetylserine2 def: "Protein TMSL2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q2KHM7] comment: By similarity xref: UniProtKB:Q2KHM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049167 ! TMSL2_HUMAN [Term] id: CCO:B0052855 name: TMSL3_HUMAN-N-acetylserine2 def: "Protein TMSL3_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:A8MW06] comment: By similarity xref: UniProtKB:A8MW06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049175 ! TMSL3_HUMAN [Term] id: CCO:B0052856 name: TMSL6_HUMAN-N-acetylserine2 def: "Protein TMSL6_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:A9Z1Y9] comment: By similarity xref: UniProtKB:A9Z1Y9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049179 ! TMSL6_HUMAN [Term] id: CCO:B0052857 name: TOP2A_HUMAN-Phosphoserine1476 def: "Protein TOP2A_HUMAN with the residue 1476 substituted with Phosphoserine" [UniProtKB:P11388] comment: By similarity xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0052858 name: TOP2A_HUMAN-Phosphoserine1504 def: "Protein TOP2A_HUMAN with the residue 1504 substituted with Phosphoserine" [UniProtKB:P11388] xref: UniProtKB:P11388 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000419 ! DNA topoisomerase activity relationship: has_function CCO:F0000421 ! DNA topoisomerase (ATP-hydrolyzing) activity relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000384 ! centriole relationship: located_in CCO:C0000578 ! DNA topoisomerase complex (ATP-hydrolyzing) relationship: located_in CCO:C0000873 ! viral integration complex relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0005803 ! TOP2A_HUMAN [Term] id: CCO:B0052883 name: TYB10_HUMAN-N-acetylalanine2 def: "Protein TYB10_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P63313] comment: By similarity xref: UniProtKB:P63313 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049178 ! TYB10_HUMAN [Term] id: CCO:B0052884 name: TYB10_HUMAN-N6-acetyllysine4 def: "Protein TYB10_HUMAN with the residue 4 substituted with N6-acetyllysine" [UniProtKB:P63313] xref: UniProtKB:P63313 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0049178 ! TYB10_HUMAN [Term] id: CCO:B0052885 name: TYB4Y_HUMAN-N-acetylserine2 def: "Protein TYB4Y_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:O14604] comment: By similarity xref: UniProtKB:O14604 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049176 ! TYB4Y_HUMAN [Term] id: CCO:B0052892 name: WDR1_HUMAN-Phosphotyrosine238 def: "Protein WDR1_HUMAN with the residue 238 substituted with Phosphotyrosine" [UniProtKB:O75083] xref: UniProtKB:O75083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0050621 ! WDR1_HUMAN [Term] id: CCO:B0053696 name: A0A502_HUMAN def: "CC-chemokine receptor" [UniProtKB:A0A502] xref: EMBL:AAC23944.1 xref: UniProtKB:A0A502 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021014 ! CCR-5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053697 name: A0AUX1_HUMAN def: "ZNF33A protein" [UniProtKB:A0AUX1] xref: EMBL:AAI26120.1 xref: UniProtKB:A0AUX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020712 ! ZNF33A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053698 name: A0AVG4_HUMAN def: "Interleukin 1 receptor accessory protein-like 1" [UniProtKB:A0AVG4] xref: EMBL:AAI26346.1 xref: EMBL:AAI26348.1 xref: EMBL:CAI42035.1 xref: EMBL:CAI42992.1 xref: EMBL:EAW99046.1 xref: UniProtKB:A0AVG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018316 ! IL1RAPL1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053699 name: A0AVJ9_HUMAN def: "Zinc finger protein 37 homolog (Mouse)" [UniProtKB:A0AVJ9] xref: EMBL:AAI26391.1 xref: UniProtKB:A0AVJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021015 ! ZFP37_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053700 name: A0JLP1_HUMAN def: "WSB1 protein" [UniProtKB:A0JLP1] xref: EMBL:AAH05226.1 xref: UniProtKB:A0JLP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020500 ! WSB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053701 name: A0JLR9_HUMAN def: "FGB protein" [UniProtKB:A0JLR9] xref: EMBL:AAH07030.1 xref: UniProtKB:A0JLR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017806 ! FGB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053702 name: MED19_HUMAN def: "Mediator of RNA polymerase II transcription subunit 19" [UniProtKB:A0JLT2] synonym: "Lung cancer metastasis-related protein 1" EXACT [UniProtKB:A0JLT2] synonym: "Mediator complex subunit 19" EXACT [UniProtKB:A0JLT2] xref: EMBL:AAH09723.1 xref: EMBL:AAH37223.1 xref: EMBL:AAN16075.1 xref: EMBL:EAW73775.1 xref: UniProtKB:A0JLT2 xref: UniProtKB:Q8IV02 xref: UniProtKB:Q8IZD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018597 ! MED19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053703 name: A0PJU7_HUMAN def: "TSHR protein" [UniProtKB:A0PJU7] xref: EMBL:AAI27629.1 xref: UniProtKB:A0PJU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020373 ! TSHR_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053704 name: FEZF1_HUMAN def: "Fez family zinc finger protein 1" [UniProtKB:A0PJY2] synonym: "Zinc finger protein 312B" EXACT [UniProtKB:A0PJY2] xref: EMBL:AAI27715.1 xref: EMBL:AAI27716.1 xref: EMBL:EAL24342.1 xref: UniProtKB:A0PJY2 xref: UniProtKB:A0PJY3 xref: UniProtKB:A4D0W3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017779 ! FEZF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053705 name: RHG10_HUMAN def: "Rho GTPase-activating protein 10" [UniProtKB:A1A4S6] synonym: "Graf-related protein 2" EXACT [UniProtKB:A1A4S6] synonym: "GTPase regulator associated with focal adhesion kinase 2" EXACT [UniProtKB:A1A4S6] synonym: "Rho-type GTPase-activating protein 10" EXACT [UniProtKB:A1A4S6] xref: EMBL:AAH11920.2 xref: EMBL:AAI09030.1 xref: EMBL:AAI09031.1 xref: EMBL:AAI26900.1 xref: EMBL:AAI28056.1 xref: EMBL:BAB61771.1 xref: UniProtKB:A1A4S6 xref: UniProtKB:A1L0S5 xref: UniProtKB:Q2VPC4 xref: UniProtKB:Q2VPC5 xref: UniProtKB:Q96EV3 xref: UniProtKB:Q96S75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019718 ! ARHGAP10_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069948 ! RHG10_HUMAN-Phosphothreonine109 relationship: transforms_into CCO:B0069949 ! RHG10_HUMAN-Phosphothreonine111 [Term] id: CCO:B0053706 name: A1A4T0_HUMAN def: "RIN2 protein" [UniProtKB:A1A4T0] xref: EMBL:AAI28066.1 xref: UniProtKB:A1A4T0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019743 ! RIN2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053707 name: A1A4T9_HUMAN def: "ZNF662 protein" [UniProtKB:A1A4T9] xref: EMBL:AAI28086.1 xref: UniProtKB:A1A4T9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020880 ! ZNF662_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053708 name: A1ECB1_HUMAN def: "NK2 transcription factor related locus 5" [UniProtKB:A1ECB1] xref: EMBL:ABL63553.1 xref: UniProtKB:A1ECB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018797 ! NKX2-5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053709 name: A1ECB2_HUMAN def: "NK2 transcription factor related locus 5" [UniProtKB:A1ECB2] xref: EMBL:ABL63554.1 xref: EMBL:ABL63555.1 xref: EMBL:ABL63556.1 xref: EMBL:ABL63557.1 xref: EMBL:ABL63563.1 xref: EMBL:ABL63564.1 xref: EMBL:ABL63576.1 xref: EMBL:ABL63582.1 xref: EMBL:ABL63588.1 xref: EMBL:ABL63593.1 xref: UniProtKB:A1ECB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018797 ! NKX2-5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053710 name: YE018_HUMAN def: "Probable guanine nucleotide exchange factor FLJ41603" [UniProtKB:A1IGU5] xref: EMBL:BAC85655.1 xref: EMBL:BAF43710.1 xref: UniProtKB:A1IGU5 xref: UniProtKB:Q6ZW51 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0053711 name: A1L156_HUMAN def: "LTB4R2 protein" [UniProtKB:A1L156] xref: EMBL:AAI19675.1 xref: EMBL:AAI27644.1 xref: UniProtKB:A1L156 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018529 ! LTB4R2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001314 ! leukotriene receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053712 name: PKHG3_HUMAN def: "Pleckstrin homology domain-containing family G member 3" [UniProtKB:A1L390] xref: EMBL:AAH04298.1 xref: EMBL:AAH11891.2 xref: EMBL:AAH63554.1 xref: EMBL:AAH73907.1 xref: EMBL:AAI29953.1 xref: EMBL:AAI29954.1 xref: EMBL:BAA25525.1 xref: EMBL:BAB84995.1 xref: EMBL:CAD66586.1 xref: UniProtKB:A1L389 xref: UniProtKB:A1L390 xref: UniProtKB:O60339 xref: UniProtKB:Q6GMS3 xref: UniProtKB:Q6P4B1 xref: UniProtKB:Q7L3S3 xref: UniProtKB:Q86SW7 xref: UniProtKB:Q8TEF5 xref: UniProtKB:Q96EW6 xref: UniProtKB:Q9BT82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019415 ! PLEKHG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0069347 ! PKHG3_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0069348 ! PKHG3_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0069349 ! PKHG3_HUMAN-Phosphoserine643 relationship: transforms_into CCO:B0069350 ! PKHG3_HUMAN-Phosphoserine647 relationship: transforms_into CCO:B0069351 ! PKHG3_HUMAN-Phosphoserine1023 relationship: transforms_into CCO:B0069352 ! PKHG3_HUMAN-Phosphoserine1037 relationship: transforms_into CCO:B0069353 ! PKHG3_HUMAN-Phosphothreonine1042 [Term] id: CCO:B0053713 name: A1L4L9_HUMAN def: "POM121C protein" [UniProtKB:A1L4L9] xref: EMBL:AAI30588.1 xref: EMBL:AAI30590.1 xref: UniProtKB:A1L4L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021016 ! POM121C_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053714 name: A2A284_HUMAN def: "Phospholipase C, gamma 1 (Phospholipase C, gamma 1, isoform CRA_b)" [UniProtKB:A2A284] xref: EMBL:CAM28260.1 xref: EMBL:EAW75990.1 xref: UniProtKB:A2A284 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005334 ! PLCG1_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053715 name: A2A2C9_HUMAN def: "V-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (Avian)" [UniProtKB:A2A2C9] xref: EMBL:CAB75682.1 xref: UniProtKB:A2A2C9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018691 ! MYCL1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053716 name: A2A2E9_HUMAN def: "OTTHUMP00000030968" [UniProtKB:A2A2E9] xref: EMBL:CAI23368.2 xref: EMBL:CAM27456.1 xref: UniProtKB:A2A2E9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021017 ! RP5-1100H13.1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053717 name: A2A3I7_HUMAN def: "Nuclear receptor subfamily 4, group A, member 3 (Nuclear receptor subfamily 4, group A, member 3, isoform CRA_a)" [UniProtKB:A2A3I7] xref: EMBL:CAM16648.1 xref: EMBL:CAM22558.1 xref: EMBL:EAW58915.1 xref: UniProtKB:A2A3I7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018862 ! NR4A3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053718 name: A2A3Q3_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A2A3Q3] xref: EMBL:CAM13080.1 xref: UniProtKB:A2A3Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053719 name: A2A3Q4_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A2A3Q4] xref: EMBL:CAM13081.1 xref: UniProtKB:A2A3Q4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053720 name: A2A3Q5_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A2A3Q5] xref: EMBL:CAM13082.2 xref: UniProtKB:A2A3Q5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053721 name: A2ABF1_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A2ABF1] xref: EMBL:CAM24985.1 xref: EMBL:CAM25672.1 xref: EMBL:CAM26108.1 xref: EMBL:CAQ07248.1 xref: EMBL:CAQ10121.1 xref: EMBL:CAQ10615.1 xref: UniProtKB:A2ABF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0053722 name: A2ABL5_HUMAN def: "General transcription factor IIH, polypeptide 4, 52kDa" [UniProtKB:A2ABL5] xref: EMBL:CAM24840.1 xref: EMBL:CAM25402.1 xref: EMBL:CAQ06760.1 xref: EMBL:CAQ09771.1 xref: EMBL:CAQ10922.1 xref: UniProtKB:A2ABL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015033 ! GTF2H4_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053723 name: A2AGP5_HUMAN def: "Zinc finger protein 169 (Zinc finger protein 169, isoform CRA_b)" [UniProtKB:A2AGP5] xref: EMBL:CAM16531.1 xref: EMBL:EAW62879.1 xref: UniProtKB:A2AGP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020638 ! ZNF169_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053724 name: A2BDZ0_HUMAN def: "Olfactory receptor family 5 subfamily V member 1" [UniProtKB:A2BDZ0] xref: EMBL:CAM25847.1 xref: UniProtKB:A2BDZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019194 ! OR5V1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053725 name: A2BDZ2_HUMAN def: "Olfactory receptor family 12 subfamily D member 2" [UniProtKB:A2BDZ2] xref: EMBL:CAM25849.1 xref: UniProtKB:A2BDZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018938 ! OR12D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053726 name: A2BEC2_HUMAN def: "Olfactory receptor family 5 subfamily U member 1" [UniProtKB:A2BEC2] xref: EMBL:CAM26129.1 xref: EMBL:CAQ07321.1 xref: EMBL:CAQ08487.1 xref: EMBL:CAQ08987.1 xref: UniProtKB:A2BEC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021018 ! OR5U1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053727 name: A2BF33_HUMAN def: "Olfactory receptor family 11 subfamily A member 1" [UniProtKB:A2BF33] xref: EMBL:CAM25998.1 xref: UniProtKB:A2BF33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018932 ! OR11A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053728 name: A2BF34_HUMAN def: "Olfactory receptor family 10 subfamily C member 1" [UniProtKB:A2BF34] xref: EMBL:CAM25999.1 xref: UniProtKB:A2BF34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018905 ! OR10C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053729 name: A2BFK5_HUMAN def: "Zinc finger protein 311" [UniProtKB:A2BFK5] xref: EMBL:CAM25873.1 xref: UniProtKB:A2BFK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020699 ! ZNF311_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053730 name: A2I2N6_HUMAN def: "cDNA FLJ38430 fis, clone FEBRA2013699, highly similar to Aryl hydrocarbon receptor nucleartranslocator-like protein 1" [UniProtKB:A2I2N6] synonym: "Aryl hydrocarbon receptor nuclear translocator-like" EXACT [UniProtKB:A2I2N6] synonym: "Aryl hydrocarbon receptor nuclear translocator-like, isoform CRA_c" EXACT [UniProtKB:A2I2N6] xref: EMBL:ABM64205.1 xref: EMBL:BAG53120.1 xref: EMBL:EAW68505.1 xref: UniProtKB:A2I2N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017165 ! ARNTL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053731 name: A2IDC6_HUMAN def: "Mitochondrial ribosomal protein L28" [UniProtKB:A2IDC6] xref: EMBL:CAM26403.1 xref: UniProtKB:A2IDC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019754 ! MRPL28_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000407 ! ribosome relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053732 name: A2IDC7_HUMAN def: "Mitochondrial ribosomal protein L28" [UniProtKB:A2IDC7] xref: EMBL:CAM26404.1 xref: UniProtKB:A2IDC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019754 ! MRPL28_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000407 ! ribosome relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053733 name: A2IDD7_HUMAN xref: UniProtKB:A2IDD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053734 name: A2RQR4_HUMAN def: "Reverse transcriptase-like protein" [UniProtKB:A2RQR4] xref: EMBL:AAW63045.1 xref: UniProtKB:A2RQR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0053735 name: A2RRB4_HUMAN def: "NFAT5 protein" [UniProtKB:A2RRB4] xref: EMBL:AAI31510.1 xref: UniProtKB:A2RRB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018770 ! NFAT5_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053736 name: ZN320_HUMAN def: "Zinc finger protein 320" [UniProtKB:A2RRD8] xref: EMBL:AAI31556.1 xref: EMBL:CAD38570.1 xref: UniProtKB:A2RRD8 xref: UniProtKB:Q8NDR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020702 ! ZNF320_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053737 name: A2RRM7_HUMAN def: "BBX protein" [UniProtKB:A2RRM7] xref: EMBL:AAI31719.1 xref: UniProtKB:A2RRM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017135 ! BBX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053738 name: A2RTX9_HUMAN xref: UniProtKB:A2RTX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053739 name: A2RU51_HUMAN def: "PRR5-ARHGAP8 fusion" [UniProtKB:A2RU51] synonym: "Rho GTPase activating protein 8" EXACT [UniProtKB:A2RU51] xref: EMBL:AAI32756.1 xref: EMBL:AAI32758.1 xref: EMBL:CAO03396.2 xref: EMBL:CAO03546.2 xref: UniProtKB:A2RU51 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021019 ! LOC553158_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053740 name: HMX2_HUMAN def: "Homeobox protein HMX2" [UniProtKB:A2RU54] synonym: "Homeobox protein H6 family member 2" EXACT [UniProtKB:A2RU54] xref: EMBL:AAI32759.1 xref: UniProtKB:A2RU54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018147 ! HMX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053741 name: A2VBQ3_HUMAN def: "Autogenous vein graft remodeling associated protein 8" [UniProtKB:A2VBQ3] xref: EMBL:CAM34545.1 xref: UniProtKB:A2VBQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021020 ! AVGR8_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053742 name: OR2M5_HUMAN def: "Olfactory receptor 2M5" [UniProtKB:A3KFT3] xref: EMBL:CAM45729.1 xref: UniProtKB:A3KFT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019112 ! OR2M5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053743 name: A3KGN1_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGN1] xref: EMBL:CAM45785.1 xref: UniProtKB:A3KGN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0053744 name: A3KGN2_HUMAN def: "MutS homolog 5 (E. coli)" [UniProtKB:A3KGN2] xref: EMBL:CAM45786.1 xref: UniProtKB:A3KGN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005129 ! MSH5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0053745 name: A3KMP8_HUMAN def: "Cas-Br-M (Murine) ecotropic retroviral transforming sequence" [UniProtKB:A3KMP8] xref: EMBL:AAI32734.1 xref: UniProtKB:A3KMP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004228 ! CBL_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0053746 name: A3KN61_HUMAN def: "BRF1 protein" [UniProtKB:A3KN61] xref: EMBL:AAI33656.1 xref: UniProtKB:A3KN61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015034 ! BRF1_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053747 name: A3KN82_HUMAN def: "RAPGEF6 protein" [UniProtKB:A3KN82] xref: EMBL:AAI33704.1 xref: UniProtKB:A3KN82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019789 ! RAPGEF6_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053748 name: A3R6R8_HUMAN def: "Type II cAMP-dependent regulatory protein kinase beta" [UniProtKB:A3R6R8] xref: EMBL:ABO15447.1 xref: UniProtKB:A3R6R8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007719 ! PRKAR2B_human relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation [Term] id: CCO:B0053749 name: A4D0Z1_HUMAN def: "Paired box gene 4 (Paired box gene 4, isoform CRA_b)" [UniProtKB:A4D0Z1] xref: EMBL:EAL24318.1 xref: EMBL:EAW83634.1 xref: UniProtKB:A4D0Z1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019308 ! PAX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053750 name: A4D182_HUMAN def: "Homeo box A3 (cDNA FLJ36881 fis, clone BGGI12001247, highly similar to HOMEOBOX PROTEIN HOX-A3)" [UniProtKB:A4D182] xref: EMBL:BAG52842.1 xref: EMBL:EAL24226.1 xref: UniProtKB:A4D182 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018180 ! HOXA3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053751 name: YG015_HUMAN def: "Leucine-rich repeat and death domain-containing protein LOC401387" [UniProtKB:A4D1F6] xref: EMBL:AAH26112.1 xref: EMBL:EAL24153.1 xref: UniProtKB:A4D1F6 xref: UniProtKB:Q49AT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053752 name: RAB19_HUMAN def: "Ras-related protein Rab-19" [UniProtKB:A4D1S5] xref: EMBL:AAF00046.1 xref: EMBL:EAL24028.1 xref: UniProtKB:A4D1S5 xref: UniProtKB:Q9UL27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019576 ! RAB19_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069672 ! RAB19_HUMAN-Cysteine methyl ester217 [Term] id: CCO:B0053753 name: A4D1S6_HUMAN def: "Similar to dGTPase-mouse" [UniProtKB:A4D1S6] synonym: "EC 3.1.5.1" EXACT [UniProtKB:A4D1S6] xref: EMBL:EAL24029.1 xref: UniProtKB:A4D1S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021021 ! LOC393004_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0002175 ! dGTPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053754 name: A4D225_HUMAN def: "Similar to vasoactive intestinal peptide receptor 2" [UniProtKB:A4D225] xref: EMBL:EAL23937.1 xref: UniProtKB:A4D225 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021022 ! LOC389604_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053755 name: A4D258_HUMAN def: "Growth factor receptor-bound protein 10 (Growth factor receptor-bound protein 10, isoform CRA_b)" [UniProtKB:A4D258] xref: EMBL:EAL23897.1 xref: EMBL:EAW60965.1 xref: UniProtKB:A4D258 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018052 ! GRB10_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053756 name: A4D299_HUMAN def: "TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa" [UniProtKB:A4D299] xref: EMBL:EAL23853.1 xref: UniProtKB:A4D299 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008417 ! TAF6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0003021 ! regulation of transcription factor activity [Term] id: CCO:B0053757 name: A4D2A4_HUMAN def: "Zinc finger protein 3 (A8-51)" [UniProtKB:A4D2A4] xref: EMBL:EAL23858.1 xref: UniProtKB:A4D2A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020973 ! ZNF3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053758 name: A4D2G2_HUMAN def: "Olfactory receptor, family 6, subfamily B, member 1" [UniProtKB:A4D2G2] xref: EMBL:EAL23796.1 xref: UniProtKB:A4D2G2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021023 ! OR6B1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053759 name: O2A25_HUMAN def: "Olfactory receptor 2A25" [UniProtKB:A4D2G3] xref: EMBL:EAL23797.1 xref: UniProtKB:A4D2G3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018956 ! OR2A25_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053760 name: A4D2L0_HUMAN def: "Similar to ELK1" [UniProtKB:A4D2L0] xref: EMBL:EAL23742.1 xref: UniProtKB:A4D2L0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021024 ! LOC402257_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053761 name: A4D2P2_HUMAN def: "Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1) (Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_b)" [UniProtKB:A4D2P2] xref: EMBL:EAL23720.1 xref: EMBL:EAW55040.1 xref: UniProtKB:A4D2P2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005411 ! RAC1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053762 name: A4FU15_HUMAN def: "DEPDC4 protein" [UniProtKB:A4FU15] xref: EMBL:AAI00931.1 xref: UniProtKB:A4FU15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017555 ! DEPDC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053763 name: A4FU53_HUMAN def: "Zinc finger protein 112 homolog (Mouse)" [UniProtKB:A4FU53] synonym: "Zinc finger protein 228, isoform CRA_b" EXACT [UniProtKB:A4FU53] xref: EMBL:AAI01754.1 xref: EMBL:EAW57269.1 xref: UniProtKB:A4FU53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021025 ! ZFP112_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053764 name: A4FU63_HUMAN def: "IL1RL2 protein" [UniProtKB:A4FU63] xref: EMBL:AAI07065.1 xref: UniProtKB:A4FU63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018276 ! IL1RL2_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053765 name: A4FVB3_HUMAN def: "SPRY4 protein" [UniProtKB:A4FVB3] xref: EMBL:AAI25097.1 xref: UniProtKB:A4FVB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020030 ! SPRY4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0053766 name: A4GU14_HUMAN def: "Regulator of calcineurin 3 isoform 2,4,5" [UniProtKB:A4GU14] xref: EMBL:ABO27184.1 xref: EMBL:ABP88933.1 xref: UniProtKB:A4GU14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021026 ! DSCR1L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0053767 name: A4LA69_HUMAN def: "Regulator of calcineurin 3 isoform 2,3,5" [UniProtKB:A4LA69] xref: EMBL:ABO46010.1 xref: UniProtKB:A4LA69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021026 ! DSCR1L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0053768 name: A4PBF7_HUMAN def: "TATA box binding protein (TBP)-associated factor 4B" [UniProtKB:A4PBF7] xref: EMBL:BAF51561.1 xref: UniProtKB:A4PBF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021027 ! taf4b_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053769 name: A4Q9G8_HUMAN def: "PRDM7 long isoform, variant 1" [UniProtKB:A4Q9G8] xref: EMBL:CAM84449.1 xref: UniProtKB:A4Q9G8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021028 ! PRDM7_V1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053770 name: A4Q9G9_HUMAN def: "PRDM7 long isoform, variant 2" [UniProtKB:A4Q9G9] xref: EMBL:CAM84450.1 xref: UniProtKB:A4Q9G9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021029 ! PRDM7_V2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053771 name: A4QMS5_HUMAN def: "LOC442421 protein" [UniProtKB:A4QMS5] xref: EMBL:AAI04193.1 xref: EMBL:AAI04194.1 xref: EMBL:AAI12987.1 xref: EMBL:AAI12988.1 xref: UniProtKB:A4QMS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021030 ! LOC442421_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053772 name: A4QPC0_HUMAN xref: UniProtKB:A4QPC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053773 name: PI4P2_HUMAN def: "Putative phosphatidylinositol 4-kinase alpha-like protein P2" [UniProtKB:A4QPH2] xref: EMBL:AAH20225.2 xref: EMBL:AAI39842.2 xref: EMBL:BAC86726.1 xref: EMBL:CAG30264.1 xref: UniProtKB:A4QPH2 xref: UniProtKB:Q6ICJ0 xref: UniProtKB:Q6ZT68 xref: UniProtKB:Q8WUK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019396 ! PI4KAP2_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0053774 name: A5PKU7_HUMAN def: "TBX4 protein" [UniProtKB:A5PKU7] xref: EMBL:AAI42621.1 xref: UniProtKB:A5PKU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021031 ! TBX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053775 name: PSD1_HUMAN def: "PH and SEC7 domain-containing protein 1" [UniProtKB:A5PKW4] synonym: "Exchange factor for ARF6" EXACT [UniProtKB:A5PKW4] synonym: "Pleckstrin homology and SEC7 domain-containing protein 1" EXACT [UniProtKB:A5PKW4] xref: EMBL:AAI42644.1 xref: EMBL:AAI42690.1 xref: EMBL:BAC23107.1 xref: EMBL:CAA68002.1 xref: EMBL:CAI12516.1 xref: EMBL:EAW49693.1 xref: UniProtKB:A5PKW4 xref: UniProtKB:B1AKX7 xref: UniProtKB:Q15673 xref: UniProtKB:Q8IVG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019524 ! PSD_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0069564 ! PSD1_HUMAN-Phosphoserine720 [Term] id: CCO:B0053776 name: A5PLP1_HUMAN def: "ZNF30 protein" [UniProtKB:A5PLP1] xref: EMBL:AAI42997.1 xref: UniProtKB:A5PLP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020969 ! ZNF30_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053777 name: A5XEI4_HUMAN def: "Guanine nucleotide-releasing factor 2" [UniProtKB:A5XEI4] xref: EMBL:ABL59904.1 xref: UniProtKB:A5XEI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053778 name: A5XEI5_HUMAN def: "Guanine nucleotide-releasing factor 2" [UniProtKB:A5XEI5] xref: EMBL:ABL59905.1 xref: UniProtKB:A5XEI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053779 name: A5XEI9_HUMAN def: "Guanine nucleotide-releasing factor 2" [UniProtKB:A5XEI9] xref: EMBL:ABL59909.1 xref: UniProtKB:A5XEI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053780 name: BDP1_HUMAN def: "Transcription factor TFIIIB component B'' homolog" [UniProtKB:A6H8Y1] synonym: "TFIIIB150" EXACT [UniProtKB:A6H8Y1] synonym: "Transcription factor IIIB 150" EXACT [UniProtKB:A6H8Y1] synonym: "Transcription factor-like nuclear regulator" EXACT [UniProtKB:A6H8Y1] xref: EMBL:AAG09268.1 xref: EMBL:AAG30220.1 xref: EMBL:AAG30221.1 xref: EMBL:AAH32146.1 xref: EMBL:AAI46793.1 xref: EMBL:BAA86555.1 xref: EMBL:BAB21780.3 xref: EMBL:BAB71602.1 xref: EMBL:CAC04245.1 xref: EMBL:CAC17771.1 xref: EMBL:CAC21448.1 xref: EMBL:CAE46010.1 xref: EMBL:CAH18085.1 xref: EMBL:CAH18144.1 xref: UniProtKB:A6H8Y1 xref: UniProtKB:Q68DS6 xref: UniProtKB:Q68DY5 xref: UniProtKB:Q6MZL9 xref: UniProtKB:Q6PIM7 xref: UniProtKB:Q86W98 xref: UniProtKB:Q96LR8 xref: UniProtKB:Q9C0H4 xref: UniProtKB:Q9H197 xref: UniProtKB:Q9H1A1 xref: UniProtKB:Q9HAW1 xref: UniProtKB:Q9HAW2 xref: UniProtKB:Q9HCY0 xref: UniProtKB:Q9ULH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017143 ! BDP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063872 ! BDP1_HUMAN-Phosphoserine2196 [Term] id: CCO:B0053781 name: A6MW40_HUMAN def: "PKDREJ" [UniProtKB:A6MW40] xref: EMBL:ABR22603.1 xref: UniProtKB:A6MW40 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0053782 name: A6NC00_HUMAN def: "Uncharacterized protein ENSP00000332379" [UniProtKB:A6NC00] xref: UniProtKB:A6NC00 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053783 name: A6NC31_HUMAN def: "Putative uncharacterized protein OR51I1" [UniProtKB:A6NC31] xref: UniProtKB:A6NC31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018994 ! OR51I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053784 name: A6NC89_HUMAN def: "Putative uncharacterized protein CNTNAP3" [UniProtKB:A6NC89] xref: UniProtKB:A6NC89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017419 ! CNTNAP3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053785 name: NKX26_HUMAN def: "Homeobox protein Nkx-2.6" [UniProtKB:A6NCS4] synonym: "Homeobox protein NK-2 homolog F" EXACT [UniProtKB:A6NCS4] xref: UniProtKB:A6NCS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018798 ! NKX2-6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053786 name: O6C74_HUMAN def: "Olfactory receptor 6C74" [UniProtKB:A6NCV1] xref: EMBL:EAW96805.1 xref: UniProtKB:A6NCV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019034 ! OR6C74_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053787 name: YB041_HUMAN def: "HMG box-containing protein LOC129870" [UniProtKB:A6ND21] xref: UniProtKB:A6ND21 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053788 name: O14I1_HUMAN def: "Olfactory receptor 14I1" [UniProtKB:A6ND48] synonym: "Olfactory receptor 5BU1" EXACT [UniProtKB:A6ND48] xref: UniProtKB:A6ND48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018951 ! OR14I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053789 name: A6ND77_HUMAN def: "Putative uncharacterized protein TBX5 (T-box 5, isoform CRA_b)" [UniProtKB:A6ND77] xref: EMBL:EAW98066.1 xref: UniProtKB:A6ND77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020198 ! TBX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053790 name: A6NDI7_HUMAN def: "Putative uncharacterized protein ARHGAP22" [UniProtKB:A6NDI7] xref: UniProtKB:A6NDI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019722 ! ARHGAP22_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053791 name: RB43L_HUMAN def: "Putative Rab-43-like protein ENSP00000330714" [UniProtKB:A6NDJ8] xref: UniProtKB:A6NDJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069762 ! RB43L_HUMAN-Cysteine methyl ester181 [Term] id: CCO:B0053792 name: A6NDL0_HUMAN def: "Putative uncharacterized protein TBC1D3E (Putative uncharacterized protein TBC1D3D) (Putative uncharacterized protein TBC1D3)" [UniProtKB:A6NDL0] xref: UniProtKB:A6NDL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021032 ! TBC1D3E_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053793 name: O6C68_HUMAN def: "Olfactory receptor 6C68" [UniProtKB:A6NDL8] xref: EMBL:EAW96814.1 xref: UniProtKB:A6NDL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019032 ! OR6C68_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053794 name: A6NDQ6_HUMAN def: "Uncharacterized protein ENSP00000242475" [UniProtKB:A6NDQ6] xref: UniProtKB:A6NDQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053795 name: A6NDS3_HUMAN def: "Uncharacterized protein ENSP00000331047" [UniProtKB:A6NDS3] xref: UniProtKB:A6NDS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053796 name: TBC3B_HUMAN def: "TBC1 domain family member 3B/I" [UniProtKB:A6NDS4] xref: EMBL:BAF84946.1 xref: UniProtKB:A6NDS4 xref: UniProtKB:A8K892 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020173 ! TBC1D3B_human relationship: encoded_by CCO:G0020174 ! TBC1D3I_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053797 name: A6NDW2_HUMAN def: "Putative uncharacterized protein GNRHR2" [UniProtKB:A6NDW2] xref: UniProtKB:A6NDW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017948 ! GNRHR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001309 ! gonadotropin-releasing hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053798 name: YT007_HUMAN def: "Putative zinc finger protein ENSP00000330248" [UniProtKB:A6NDX5] xref: UniProtKB:A6NDX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053799 name: A6NDX7_HUMAN def: "Putative uncharacterized protein ZKSCAN4" [UniProtKB:A6NDX7] xref: UniProtKB:A6NDX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020611 ! ZKSCAN4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053800 name: A6NE11_HUMAN def: "Putative uncharacterized protein LPHN2" [UniProtKB:A6NE11] xref: UniProtKB:A6NE11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0053801 name: A6NE42_HUMAN def: "cDNA FLJ76181, highly similar to Homo sapiens TGFB-induced factor (TALE family homeobox) (TGIF), transcript variant 2, mRNA" [UniProtKB:A6NE42] synonym: "Putative uncharacterized protein TGIF1" EXACT [UniProtKB:A6NE42] xref: EMBL:BAF83801.1 xref: UniProtKB:A6NE42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005777 ! TGIF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053802 name: A6NE50_HUMAN def: "Putative uncharacterized protein TBC1D3F" [UniProtKB:A6NE50] xref: UniProtKB:A6NE50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021033 ! TBC1D3F_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053803 name: A6NE61_HUMAN def: "Protein Wnt" [UniProtKB:A6NE61] xref: UniProtKB:A6NE61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020479 ! WNT10B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0053804 name: A6NE74_HUMAN def: "Putative uncharacterized protein ATPIF1" [UniProtKB:A6NE74] xref: UniProtKB:A6NE74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021034 ! ATPIF1_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0002656 ! negative regulation of nucleotide metabolic process [Term] id: CCO:B0053805 name: A6NE96_HUMAN def: "Putative uncharacterized protein OR10J1" [UniProtKB:A6NE96] xref: UniProtKB:A6NE96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018919 ! OR10J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053806 name: A6NEC7_HUMAN def: "Putative uncharacterized protein AKAP12" [UniProtKB:A6NEC7] xref: UniProtKB:A6NEC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016941 ! AKAP12_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053807 name: A6NEF2_HUMAN xref: UniProtKB:A6NEF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053808 name: SSX10_HUMAN def: "Protein SSX10" [UniProtKB:A6NEJ1] xref: UniProtKB:A6NEJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020045 ! SSX10_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053809 name: TBC3E_HUMAN def: "TBC1 domain family member 3E/3F" [UniProtKB:A6NER0] xref: UniProtKB:A6NER0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021032 ! TBC1D3E_human relationship: encoded_by CCO:G0021033 ! TBC1D3F_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053810 name: A6NEV2_HUMAN def: "Putative uncharacterized protein WNT1" [UniProtKB:A6NEV2] xref: UniProtKB:A6NEV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020484 ! WNT1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway [Term] id: CCO:B0053811 name: A6NF00_HUMAN def: "Putative uncharacterized protein LAMA2" [UniProtKB:A6NF00] xref: UniProtKB:A6NF00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021035 ! LAMA2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0053812 name: A6NF07_HUMAN def: "Putative uncharacterized protein ZNF671 (Zinc finger protein 671, isoform CRA_b)" [UniProtKB:A6NF07] xref: EMBL:EAW72529.1 xref: UniProtKB:A6NF07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020887 ! ZNF671_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053813 name: A6NF12_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:A6NF12] synonym: "EC 2.7.10.1" EXACT [UniProtKB:A6NF12] xref: UniProtKB:A6NF12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018885 ! NTRK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0053814 name: YS053_HUMAN def: "Putative zinc finger LOC730051" [UniProtKB:A6NF35] xref: UniProtKB:A6NF35 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053815 name: ZN734_HUMAN def: "Zinc finger protein 734" [UniProtKB:A6NF79] xref: UniProtKB:A6NF79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022815 ! ZNF734_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053816 name: OR6C6_HUMAN def: "Olfactory receptor 6C6" [UniProtKB:A6NF89] xref: UniProtKB:A6NF89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019202 ! OR6C6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053817 name: OR2W5_HUMAN def: "Putative olfactory receptor 2W5" [UniProtKB:A6NFC9] xref: EMBL:AAI37205.1 xref: UniProtKB:A6NFC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022480 ! OR2W5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053818 name: A6NFD6_HUMAN def: "Uncharacterized protein ENSP00000373892" [UniProtKB:A6NFD6] xref: UniProtKB:A6NFD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053819 name: HELT_HUMAN def: "Hairy and enhancer of split-related protein HELT" [UniProtKB:A6NFD8] synonym: "HES/HEY-like transcription factor" EXACT [UniProtKB:A6NFD8] xref: EMBL:AAI40796.1 xref: EMBL:EAX04657.1 xref: UniProtKB:A6NFD8 xref: UniProtKB:B2RTS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022305 ! HELT_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053820 name: A6NFE1_HUMAN def: "Putative uncharacterized protein ZNF397OS" [UniProtKB:A6NFE1] xref: UniProtKB:A6NFE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020527 ! ZNF397OS_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053821 name: ZN316_HUMAN def: "Zinc finger protein 316" [UniProtKB:A6NFI3] xref: UniProtKB:A6NFI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022806 ! ZNF316_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053822 name: A6NFK4_HUMAN def: "Putative uncharacterized protein ARHGEF11" [UniProtKB:A6NFK4] xref: UniProtKB:A6NFK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017020 ! ARHGEF11_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0053823 name: DPRX_HUMAN def: "Divergent paired-related homeobox" [UniProtKB:A6NFQ7] xref: UniProtKB:A6NFQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017613 ! DPRX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053824 name: A6NFR0_HUMAN def: "Putative uncharacterized protein OR4Q2" [UniProtKB:A6NFR0] xref: UniProtKB:A6NFR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019171 ! OR4Q2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053825 name: A6NFW9_HUMAN xref: UniProtKB:A6NFW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053826 name: A6NG20_HUMAN def: "Putative uncharacterized protein FOSL2 (FOS-like antigen 2, isoform CRA_c)" [UniProtKB:A6NG20] xref: EMBL:EAX00540.1 xref: UniProtKB:A6NG20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017820 ! FOSL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053827 name: A6NG39_HUMAN def: "Putative uncharacterized protein GPR110" [UniProtKB:A6NG39] xref: UniProtKB:A6NG39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017954 ! GPR110_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0053828 name: A6NG70_HUMAN def: "Putative uncharacterized protein PMS2L3" [UniProtKB:A6NG70] xref: UniProtKB:A6NG70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019453 ! PMS2L3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053829 name: A6NG83_HUMAN def: "Putative uncharacterized protein ZSCAN2" [UniProtKB:A6NG83] xref: UniProtKB:A6NG83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021008 ! ZSCAN2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053830 name: A6NG99_HUMAN def: "Putative uncharacterized protein TBC1D3C" [UniProtKB:A6NG99] xref: UniProtKB:A6NG99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020175 ! TBC1D3C_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053831 name: ZSA5C_HUMAN def: "Zinc finger and SCAN domain-containing protein 5C" [UniProtKB:A6NGD5] xref: UniProtKB:A6NGD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022831 ! ZSCAN5C_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053832 name: YR003_HUMAN def: "Putative zinc finger protein ENSP00000328166" [UniProtKB:A6NGH9] xref: UniProtKB:A6NGH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053833 name: A6NGS5_HUMAN def: "Putative uncharacterized protein LAMA2" [UniProtKB:A6NGS5] xref: UniProtKB:A6NGS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021035 ! LAMA2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0053834 name: A6NGT9_HUMAN def: "Putative uncharacterized protein OR51B6" [UniProtKB:A6NGT9] xref: UniProtKB:A6NGT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018986 ! OR51B6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053835 name: O51F1_HUMAN def: "Olfactory receptor 51F1" [UniProtKB:A6NGY5] xref: UniProtKB:A6NGY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018990 ! OR51F1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053836 name: OR2T8_HUMAN def: "Olfactory receptor 2T8" [UniProtKB:A6NH00] xref: UniProtKB:A6NH00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019121 ! OR2T8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053837 name: ZB12L_HUMAN def: "Putative zinc finger and BTB domain-containing protein 12-like protein" [UniProtKB:A6NH08] xref: UniProtKB:A6NH08 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053838 name: TBC3L_HUMAN def: "TBC1 domain family member 3-like protein LOC729837" [UniProtKB:A6NH17] xref: UniProtKB:A6NH17 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053839 name: A6NH54_HUMAN def: "Putative uncharacterized protein OR4C12" [UniProtKB:A6NH54] xref: UniProtKB:A6NH54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019139 ! OR4C12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053840 name: ARL5C_HUMAN def: "Putative ADP-ribosylation factor-like protein 5C" [UniProtKB:A6NH57] synonym: "ADP-ribosylation factor-like protein 12" EXACT [UniProtKB:A6NH57] xref: UniProtKB:A6NH57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017039 ! ARL5C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053841 name: A6NH61_HUMAN def: "Putative uncharacterized protein ZNF789" [UniProtKB:A6NH61] xref: UniProtKB:A6NH61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020942 ! ZNF789_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053842 name: A6NH69_HUMAN xref: UniProtKB:A6NH69 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053843 name: A6NH73_HUMAN def: "Putative uncharacterized protein MAX" [UniProtKB:A6NH73] xref: UniProtKB:A6NH73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005033 ! MAX_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053844 name: A6NH88_HUMAN def: "Putative uncharacterized protein TWIST1" [UniProtKB:A6NH88] xref: UniProtKB:A6NH88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020385 ! TWIST1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053845 name: O4C46_HUMAN def: "Olfactory receptor 4C46" [UniProtKB:A6NHA9] xref: UniProtKB:A6NHA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018976 ! OR4C46_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053846 name: A6NHE2_HUMAN def: "Putative uncharacterized protein RASGRP2" [UniProtKB:A6NHE2] xref: UniProtKB:A6NHE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018076 ! RASGRP2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053847 name: A6NHG8_HUMAN def: "Putative uncharacterized protein TRAF3" [UniProtKB:A6NHG8] xref: UniProtKB:A6NHG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020340 ! TRAF3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0053848 name: ZN860_HUMAN def: "Zinc finger protein 860" [UniProtKB:A6NHJ4] xref: EMBL:BAG57365.1 xref: UniProtKB:A6NHJ4 xref: UniProtKB:B4DFA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022824 ! ZNF860_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053849 name: A6NHK6_HUMAN def: "Uncharacterized protein ENSP00000357135" [UniProtKB:A6NHK6] xref: UniProtKB:A6NHK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053850 name: MOXD2_HUMAN def: "Putative DBH-like monooxygenase protein 2 precursor" [UniProtKB:A6NHM9] synonym: "EC 1.14.17.-" EXACT [UniProtKB:A6NHM9] xref: UniProtKB:A6NHM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018647 ! MOXD2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0000897 ! dopamine beta-monooxygenase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000887 ! cellular process [Term] id: CCO:B0053851 name: HMX3_HUMAN def: "Homeobox protein HMX3" [UniProtKB:A6NHT5] synonym: "Homeobox protein H6 family member 3" EXACT [UniProtKB:A6NHT5] synonym: "Homeobox protein Nkx-5.1" EXACT [UniProtKB:A6NHT5] xref: EMBL:EAW49289.1 xref: UniProtKB:A6NHT5 xref: UniProtKB:A8MU06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018148 ! HMX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053852 name: A6NHV0_HUMAN xref: UniProtKB:A6NHV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053853 name: A6NHY0_HUMAN def: "Putative uncharacterized protein ZNF568" [UniProtKB:A6NHY0] xref: UniProtKB:A6NHY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020825 ! ZNF568_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053854 name: YE015_HUMAN def: "Ankyrin repeat and death domain-containing protein ENSP00000345065" [UniProtKB:A6NHY2] xref: UniProtKB:A6NHY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053855 name: MSGN1_HUMAN def: "Mesogenin-1" [UniProtKB:A6NI15] xref: UniProtKB:A6NI15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018664 ! MSGN1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053856 name: A6NI23_HUMAN def: "Putative uncharacterized protein ZNF416" [UniProtKB:A6NI23] xref: UniProtKB:A6NI23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020739 ! ZNF416_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053857 name: RH10L_HUMAN def: "Rho GTPase-activating protein 10-like" [UniProtKB:A6NI28] xref: UniProtKB:A6NI28 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069924 ! RH10L_HUMAN-Phosphotyrosine378 [Term] id: CCO:B0053858 name: TB3L2_HUMAN def: "TBC1 domain family member 3C-like protein ENSP00000341742" [UniProtKB:A6NI40] xref: UniProtKB:A6NI40 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053859 name: A6NIB0_HUMAN def: "Putative uncharacterized protein RASGEF1A" [UniProtKB:A6NIB0] xref: UniProtKB:A6NIB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019691 ! RASGEF1A_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053860 name: A6NIF2_HUMAN def: "Putative uncharacterized protein IQSEC3" [UniProtKB:A6NIF2] xref: UniProtKB:A6NIF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018307 ! IQSEC3_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0053861 name: A6NIH4_HUMAN def: "Putative uncharacterized protein OR51I1" [UniProtKB:A6NIH4] xref: UniProtKB:A6NIH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018994 ! OR51I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053862 name: O6C70_HUMAN def: "Olfactory receptor 6C70" [UniProtKB:A6NIJ9] xref: EMBL:EAW96813.1 xref: UniProtKB:A6NIJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019033 ! OR6C70_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053863 name: A6NIQ0_HUMAN def: "Uncharacterized protein ENSP00000349693" [UniProtKB:A6NIQ0] xref: UniProtKB:A6NIQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053864 name: A6NIS4_HUMAN def: "Putative uncharacterized protein HOXD11" [UniProtKB:A6NIS4] xref: UniProtKB:A6NIS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018190 ! HOXD11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053865 name: A6NIT7_HUMAN xref: UniProtKB:A6NIT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0053866 name: A6NJ05_HUMAN def: "Putative uncharacterized protein OR10C1" [UniProtKB:A6NJ05] xref: UniProtKB:A6NJ05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018905 ! OR10C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053867 name: A6NJ28_HUMAN def: "Putative uncharacterized protein RASGRP2" [UniProtKB:A6NJ28] xref: UniProtKB:A6NJ28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018076 ! RASGRP2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053868 name: A6NJ38_HUMAN def: "Putative uncharacterized protein ARHGAP22" [UniProtKB:A6NJ38] xref: UniProtKB:A6NJ38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019722 ! ARHGAP22_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053869 name: A6NJ96_HUMAN def: "Putative uncharacterized protein CNIH4" [UniProtKB:A6NJ96] xref: UniProtKB:A6NJ96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017403 ! CNIH4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053870 name: ARGFX_HUMAN def: "Arginine-fifty homeobox" [UniProtKB:A6NJG6] xref: UniProtKB:A6NJG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017012 ! ARGFX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053871 name: A6NJH0_HUMAN def: "Uncharacterized protein ENSP00000340787" [UniProtKB:A6NJH0] xref: UniProtKB:A6NJH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053872 name: A6NJJ3_HUMAN xref: UniProtKB:A6NJJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053873 name: ZSA5B_HUMAN def: "Zinc finger and SCAN domain-containing protein 5B" [UniProtKB:A6NJL1] xref: UniProtKB:A6NJL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022830 ! ZSCAN5B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053874 name: UNC4_HUMAN def: "Homeobox protein unc-4 homolog" [UniProtKB:A6NJT0] synonym: "Homeobox protein Uncx4.1" EXACT [UniProtKB:A6NJT0] xref: EMBL:EAL23940.1 xref: UniProtKB:A4D221 xref: UniProtKB:A6NJT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020411 ! UNCX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053875 name: O6C65_HUMAN def: "Olfactory receptor 6C65" [UniProtKB:A6NJZ3] xref: UniProtKB:A6NJZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019031 ! OR6C65_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053876 name: YI017_HUMAN def: "Putative zinc finger protein ENSP00000351689" [UniProtKB:A6NK21] xref: UniProtKB:A6NK21 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053877 name: YM010_HUMAN def: "Putative zinc finger protein ENSP00000344568" [UniProtKB:A6NK31] xref: UniProtKB:A6NK31 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053878 name: ZN233_HUMAN def: "Zinc finger protein 233" [UniProtKB:A6NK53] xref: EMBL:AAO45841.1 xref: UniProtKB:A6NK53 xref: UniProtKB:Q86WL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020671 ! ZNF233_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053879 name: A6NK59_HUMAN def: "Putative uncharacterized protein ASB14" [UniProtKB:A6NK59] xref: UniProtKB:A6NK59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021036 ! ASB14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053880 name: RASFA_HUMAN def: "Ras association domain-containing protein 10" [UniProtKB:A6NK89] xref: UniProtKB:A6NK89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019628 ! RASSF10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053881 name: A6NKB0_HUMAN xref: UniProtKB:A6NKB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053882 name: A6NKC6_HUMAN def: "Putative uncharacterized protein RP1L1" [UniProtKB:A6NKC6] xref: UniProtKB:A6NKC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019774 ! RP1L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053883 name: ARI3C_HUMAN def: "AT-rich interactive domain-containing protein 3C" [UniProtKB:A6NKF2] synonym: "ARID domain-containing protein 3C" EXACT [UniProtKB:A6NKF2] xref: UniProtKB:A6NKF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017030 ! ARID3C_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053884 name: A6NKG8_HUMAN def: "Putative uncharacterized protein DVL1 (Dishevelled, dsh homolog 1 (Drosophila), isoform CRA_c) (Uncharacterized protein ENSP00000383624)" [UniProtKB:A6NKG8] xref: EMBL:EAW56226.1 xref: UniProtKB:A6NKG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017645 ! DVL1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053885 name: A6NKJ3_HUMAN def: "Putative uncharacterized protein VAV2" [UniProtKB:A6NKJ3] xref: UniProtKB:A6NKJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020434 ! VAV2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0053886 name: A6NKK7_HUMAN def: "Putative uncharacterized protein RGR" [UniProtKB:A6NKK7] xref: UniProtKB:A6NKK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019701 ! RGR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053887 name: A6NKM1_HUMAN def: "Putative uncharacterized protein ENSP00000373044" [UniProtKB:A6NKM1] xref: UniProtKB:A6NKM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053888 name: A6NKV9_HUMAN xref: UniProtKB:A6NKV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0053889 name: ZN733_HUMAN def: "Zinc finger protein 733" [UniProtKB:A6NKZ1] xref: UniProtKB:A6NKZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022814 ! ZNF733_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053890 name: O6C75_HUMAN def: "Olfactory receptor 6C75" [UniProtKB:A6NL08] xref: EMBL:EAW96808.1 xref: UniProtKB:A6NL08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019035 ! OR6C75_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053891 name: A6NL09_HUMAN def: "Putative uncharacterized protein REV3L" [UniProtKB:A6NL09] xref: UniProtKB:A6NL09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017612 ! REV3L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0053892 name: OR5BL_HUMAN def: "Olfactory receptor 5B21" [UniProtKB:A6NL26] xref: UniProtKB:A6NL26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019179 ! OR5B21_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053893 name: A6NL96_HUMAN def: "Uncharacterized protein ENSP00000368991" [UniProtKB:A6NL96] xref: UniProtKB:A6NL96 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053894 name: YE016_HUMAN def: "Putative TAF11-like protein ENSP00000332601" [UniProtKB:A6NLC8] xref: EMBL:EAX08007.1 xref: UniProtKB:A6NLC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053895 name: EA3L2_HUMAN def: "RNA polymerase II transcription factor SIII subunit A3-like-2" [UniProtKB:A6NLF2] synonym: "EloA3-like-2" EXACT [UniProtKB:A6NLF2] synonym: "Elongin-A3-like-2" EXACT [UniProtKB:A6NLF2] synonym: "Transcription elongation factor B polypeptide 3C-like-2" EXACT [UniProtKB:A6NLF2] xref: UniProtKB:A6NLF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022206 ! TCEB3CL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053896 name: A6NLG4_HUMAN def: "cDNA FLJ38019 fis, clone CTONG2012758, highly similar to Short stature homeobox protein 2" [UniProtKB:A6NLG4] synonym: "HCG1786841, isoform CRA_b" EXACT [UniProtKB:A6NLG4] synonym: "Putative uncharacterized protein SHOX2" EXACT [UniProtKB:A6NLG4] xref: EMBL:BAG53030.1 xref: EMBL:EAW78696.1 xref: UniProtKB:A6NLG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019899 ! SHOX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053897 name: A6NLH6_HUMAN def: "Putative uncharacterized protein CNIH4" [UniProtKB:A6NLH6] xref: UniProtKB:A6NLH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017403 ! CNIH4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053898 name: A6NLR4_HUMAN def: "Putative uncharacterized protein PMS2L5" [UniProtKB:A6NLR4] xref: UniProtKB:A6NLR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011846 ! PMS2L5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0053899 name: A6NLU7_HUMAN def: "Putative uncharacterized protein TGIF1 (TGFB-induced factor (TALE family homeobox), isoform CRA_c)" [UniProtKB:A6NLU7] xref: EMBL:EAX01672.1 xref: UniProtKB:A6NLU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005777 ! TGIF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053900 name: A6NLV7_HUMAN def: "Putative uncharacterized protein ZNF429" [UniProtKB:A6NLV7] xref: UniProtKB:A6NLV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011755 ! ZNF429_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053901 name: DUXA_HUMAN def: "Double homeobox protein A" [UniProtKB:A6NLW8] xref: UniProtKB:A6NLW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017643 ! DUXA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053902 name: O2AG2_HUMAN def: "Olfactory receptor 2AG2" [UniProtKB:A6NM03] xref: UniProtKB:A6NM03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018959 ! OR2AG2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053903 name: ZFP92_HUMAN def: "Zinc finger protein 92 homolog" [UniProtKB:A6NM28] synonym: "Zfp-92" EXACT [UniProtKB:A6NM28] xref: UniProtKB:A6NM28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020596 ! ZFP92_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053904 name: O6C76_HUMAN def: "Olfactory receptor 6C76" [UniProtKB:A6NM76] xref: UniProtKB:A6NM76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019036 ! OR6C76_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053905 name: A6NM80_HUMAN def: "Uncharacterized protein ENSP00000364380" [UniProtKB:A6NM80] xref: UniProtKB:A6NM80 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053906 name: A6NMI4_HUMAN def: "Putative GTP-binding protein RAY-like variant" [UniProtKB:A6NMI4] synonym: "Putative uncharacterized protein RABL4" EXACT [UniProtKB:A6NMI4] xref: EMBL:BAD92661.1 xref: UniProtKB:A6NMI4 xref: UniProtKB:Q59FN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019634 ! RABL4_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053907 name: A6NMM4_HUMAN def: "Putative uncharacterized protein CHD5" [UniProtKB:A6NMM4] xref: UniProtKB:A6NMM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017350 ! CHD5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053908 name: O52A4_HUMAN def: "Putative olfactory receptor 52A4" [UniProtKB:A6NMU1] xref: UniProtKB:A6NMU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019003 ! OR52A4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053909 name: A6NMV7_HUMAN def: "Putative uncharacterized protein HCRTR1" [UniProtKB:A6NMV7] xref: UniProtKB:A6NMV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019250 ! HCRTR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003180 ! orexin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053910 name: O4C45_HUMAN def: "Olfactory receptor 4C45" [UniProtKB:A6NMZ5] xref: UniProtKB:A6NMZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018975 ! OR4C45_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053911 name: A6NN09_HUMAN def: "Uncharacterized protein ENSP00000344387" [UniProtKB:A6NN09] xref: UniProtKB:A6NN09 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053912 name: YS032_HUMAN def: "Zinc finger protein ENSP00000350085" [UniProtKB:A6NN14] xref: UniProtKB:A6NN14 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053913 name: DRGX_HUMAN def: "Dorsal root ganglia homeobox protein" [UniProtKB:A6NNA5] synonym: "Paired-related homeobox protein-like 1" EXACT [UniProtKB:A6NNA5] xref: EMBL:EAW93100.1 xref: UniProtKB:A6NNA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017623 ! DRGX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053914 name: O2AT4_HUMAN def: "Olfactory receptor 2AT4" [UniProtKB:A6NND4] synonym: "Olfactory receptor OR11-265" EXACT [UniProtKB:A6NND4] xref: UniProtKB:A6NND4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018963 ! OR2AT4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053915 name: YS047_HUMAN def: "Zinc finger protein LOC730087" [UniProtKB:A6NNF4] xref: EMBL:AAH46415.2 xref: UniProtKB:A6NNF4 xref: UniProtKB:Q86Y87 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053916 name: A6NNH7_HUMAN def: "Putative uncharacterized protein OCRL" [UniProtKB:A6NNH7] xref: UniProtKB:A6NNH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019038 ! OCRL_human relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053917 name: A6NNL3_HUMAN def: "Uncharacterized protein ENSP00000347817" [UniProtKB:A6NNL3] xref: UniProtKB:A6NNL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053918 name: A6NNU8_HUMAN def: "Putative uncharacterized protein NR0B1" [UniProtKB:A6NNU8] xref: UniProtKB:A6NNU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018847 ! NR0B1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053919 name: SSX11_HUMAN def: "Protein SSX11" [UniProtKB:A6NNU9] xref: UniProtKB:A6NNU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020046 ! SSX11_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053920 name: YA036_HUMAN def: "RIIa domain-containing protein ENSP00000357824" [UniProtKB:A6NNX1] xref: EMBL:EAW53418.1 xref: UniProtKB:A6NNX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053921 name: A6NNY4_HUMAN def: "Putative uncharacterized protein RGR" [UniProtKB:A6NNY4] xref: UniProtKB:A6NNY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019701 ! RGR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053922 name: A6NNY6_HUMAN def: "Putative uncharacterized protein C1orf89" [UniProtKB:A6NNY6] xref: UniProtKB:A6NNY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017201 ! C1orf89_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053923 name: ZN716_HUMAN def: "Zinc finger protein 716" [UniProtKB:A6NP11] xref: UniProtKB:A6NP11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022811 ! ZNF716_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053924 name: A6PVD2_HUMAN def: "SRY (Sex determining region Y)-box 10" [UniProtKB:A6PVD2] xref: EMBL:CAO72040.1 xref: UniProtKB:A6PVD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019989 ! SOX10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053925 name: A6PVD3_HUMAN def: "SRY (Sex determining region Y)-box 10" [UniProtKB:A6PVD3] xref: EMBL:CAO72041.1 xref: UniProtKB:A6PVD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019989 ! SOX10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053926 name: A6PVQ1_HUMAN def: "LIM homeobox 6" [UniProtKB:A6PVQ1] xref: EMBL:CAO03566.1 xref: UniProtKB:A6PVQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018489 ! LHX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053927 name: A6PVQ2_HUMAN def: "LIM homeobox 6" [UniProtKB:A6PVQ2] xref: EMBL:CAO03565.1 xref: UniProtKB:A6PVQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018489 ! LHX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053928 name: A6PVV8_HUMAN def: "Phosphatidylinositol 4-kinase, catalytic, beta polypeptide" [UniProtKB:A6PVV8] xref: EMBL:CAO72153.1 xref: UniProtKB:A6PVV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021038 ! PIK4CB_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0053929 name: A6PVW1_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A6PVW1] xref: EMBL:CAO72156.1 xref: UniProtKB:A6PVW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053930 name: A6PVW2_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A6PVW2] xref: EMBL:CAO72157.1 xref: UniProtKB:A6PVW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053931 name: A6PVW3_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A6PVW3] xref: EMBL:CAO72158.1 xref: UniProtKB:A6PVW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053932 name: A6PVW4_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A6PVW4] xref: EMBL:CAO72159.1 xref: UniProtKB:A6PVW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053933 name: A6PVW5_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A6PVW5] xref: EMBL:CAO72160.1 xref: UniProtKB:A6PVW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053934 name: A6PVW7_HUMAN def: "Regulatory factor X, 5 (Influences HLA class II expression)" [UniProtKB:A6PVW7] xref: EMBL:CAO72162.1 xref: UniProtKB:A6PVW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053935 name: A6PVX5_HUMAN def: "Sorting nexin family member 27" [UniProtKB:A6PVX5] xref: EMBL:CAO03623.1 xref: UniProtKB:A6PVX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019971 ! SNX27_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053936 name: A6PVY9_HUMAN def: "Nescient helix loop helix 2" [UniProtKB:A6PVY9] xref: EMBL:CAO03390.1 xref: UniProtKB:A6PVY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018116 ! NHLH2_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053937 name: A6PW55_HUMAN def: "Vacuolar protein sorting 72 homolog (S. cerevisiae)" [UniProtKB:A6PW55] xref: EMBL:CAO72042.1 xref: UniProtKB:A6PW55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005906 ! VPS72_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053938 name: A6QRG9_HUMAN def: "Plexin B2" [UniProtKB:A6QRG9] xref: EMBL:CAO03497.1 xref: UniProtKB:A6QRG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005341 ! PLXNB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053939 name: A6QRH2_HUMAN def: "Plexin B2" [UniProtKB:A6QRH2] xref: EMBL:CAO03500.1 xref: UniProtKB:A6QRH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005341 ! PLXNB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053940 name: A6XAE6_HUMAN def: "E74-like factor 5 short form" [UniProtKB:A6XAE6] xref: EMBL:AAZ98848.1 xref: UniProtKB:A6XAE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017685 ! ELF5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053941 name: A6YCE1_HUMAN def: "Protein kinase A regulatory subunit type I/alpha-retinoic acid receptor alpha fusion protein isoform a" [UniProtKB:A6YCE1] xref: EMBL:ABR57508.1 xref: UniProtKB:A6YCE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021039 ! PRKAR1A/RARA fusion_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053942 name: A6YCE2_HUMAN def: "Protein kinase A regulatory subunit type I/alpha-retinoic acid receptor alpha fusion protein isoform b" [UniProtKB:A6YCE2] xref: EMBL:ABR57509.1 xref: UniProtKB:A6YCE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021039 ! PRKAR1A/RARA fusion_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053943 name: A6ZJ79_HUMAN def: "Rho GTPase activating protein 8" [UniProtKB:A6ZJ79] xref: EMBL:CAO03394.1 xref: EMBL:CAO03544.1 xref: UniProtKB:A6ZJ79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005481 ! ARHGAP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053944 name: A7E244_HUMAN def: "TBC1 domain family, member 10A" [UniProtKB:A7E244] xref: EMBL:AAI50188.1 xref: UniProtKB:A7E244 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020153 ! TBC1D10A_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053945 name: A7E2C7_HUMAN def: "MYT1L protein" [UniProtKB:A7E2C7] xref: EMBL:AAI50282.1 xref: UniProtKB:A7E2C7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005152 ! MYT1L_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053946 name: A7E2X8_HUMAN def: "TBC1D4 protein" [UniProtKB:A7E2X8] xref: EMBL:AAI51240.1 xref: UniProtKB:A7E2X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021040 ! TBC1D4_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053947 name: RICS_HUMAN def: "Rho/Cdc42/Rac GTPase-activating protein RICS" [UniProtKB:A7KAX9] synonym: "Brain-specific Rho GTPase-activating protein" EXACT [UniProtKB:A7KAX9] synonym: "GAB-associated Cdc42/Rac GTPase-activating protein" EXACT [UniProtKB:A7KAX9] synonym: "GC-GAP" EXACT [UniProtKB:A7KAX9] synonym: "GTPase regulator interacting with TrkA" EXACT [UniProtKB:A7KAX9] synonym: "p200RhoGAP" EXACT [UniProtKB:A7KAX9] synonym: "p250GAP" EXACT [UniProtKB:A7KAX9] synonym: "RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling" EXACT [UniProtKB:A7KAX9] xref: EMBL:AAH00277.2 xref: EMBL:AAI04899.1 xref: EMBL:AAI13430.1 xref: EMBL:AAO43677.1 xref: EMBL:ABO33171.1 xref: EMBL:BAA34432.2 xref: EMBL:BAC24802.1 xref: EMBL:EAW67740.1 xref: UniProtKB:A7KAX9 xref: UniProtKB:O94820 xref: UniProtKB:Q86YL6 xref: UniProtKB:Q8IUG4 xref: UniProtKB:Q9BWG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022567 ! RICS_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070018 ! RICS_HUMAN-Phosphoserine856 relationship: transforms_into CCO:B0070019 ! RICS_HUMAN-Phosphoserine892 relationship: transforms_into CCO:B0070020 ! RICS_HUMAN-Phosphoserine952 [Term] id: CCO:B0053948 name: A7L9S6_HUMAN def: "Receptor activity modifying protein 2" [UniProtKB:A7L9S6] xref: EMBL:ABS28868.1 xref: UniProtKB:A7L9S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021041 ! RAMP2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053949 name: A7LQ08_HUMAN def: "Truncated progesterone receptor" [UniProtKB:A7LQ08] xref: EMBL:AAO61671.1 xref: UniProtKB:A7LQ08 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053950 name: A7XAK3_HUMAN def: "Capicua-like protein/double homeodomain 4 fusion protein" [UniProtKB:A7XAK3] xref: EMBL:ABD61704.1 xref: UniProtKB:A7XAK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021042 ! CIC/DUX4 fusion_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053951 name: A8K007_HUMAN def: "cDNA FLJ77836, highly similar to Homo sapiens TBC1 domain family, member 3 (TBC1D3), mRNA" [UniProtKB:A8K007] xref: EMBL:BAF82061.1 xref: UniProtKB:A8K007 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053952 name: A8K014_HUMAN def: "cDNA FLJ76503, highly similar to Homo sapiens cAMP responsive element modulator (CREM), transcript variant 8, mRNA" [UniProtKB:A8K014] xref: EMBL:BAF82068.1 xref: UniProtKB:A8K014 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053953 name: A8K0G1_HUMAN def: "Protein Wnt" [UniProtKB:A8K0G1] xref: EMBL:BAF82215.1 xref: UniProtKB:A8K0G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0053954 name: A8K1J1_HUMAN def: "cDNA FLJ77528" [UniProtKB:A8K1J1] xref: EMBL:BAF82595.1 xref: UniProtKB:A8K1J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053955 name: A8K1S9_HUMAN def: "cDNA FLJ78363" [UniProtKB:A8K1S9] xref: EMBL:BAF82683.1 xref: UniProtKB:A8K1S9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053956 name: A8K234_HUMAN xref: UniProtKB:A8K234 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053957 name: A8K2J1_HUMAN def: "cDNA FLJ77971" [UniProtKB:A8K2J1] xref: EMBL:BAF82945.1 xref: UniProtKB:A8K2J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053958 name: A8K2Y1_HUMAN def: "cDNA FLJ78435, highly similar to Homo sapiens Rho GTPase activating protein 25 (ARHGAP25), transcript variant 1, mRNA" [UniProtKB:A8K2Y1] xref: EMBL:BAF83085.1 xref: UniProtKB:A8K2Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053959 name: A8K2Y6_HUMAN def: "cDNA FLJ75356, highly similar to Homo sapiens egf-like module containing, mucin-like, hormone receptor-like 1 (EMR1), mRNA" [UniProtKB:A8K2Y6] xref: EMBL:BAF83090.1 xref: UniProtKB:A8K2Y6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0053960 name: A8K305_HUMAN def: "cDNA FLJ75637, highly similar to Homo sapiens succinate receptor 1 (SUCNR1), mRNA (Succinate receptor 1, isoform CRA_a) (Succinate receptor 1)" [UniProtKB:A8K305] xref: EMBL:ABY87909.1 xref: EMBL:BAF83109.1 xref: EMBL:EAW78789.1 xref: UniProtKB:A8K305 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021043 ! SUCNR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0053961 name: A8K3A2_HUMAN def: "cDNA FLJ77789" [UniProtKB:A8K3A2] xref: EMBL:BAF83206.1 xref: UniProtKB:A8K3A2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0053962 name: A8K3C0_HUMAN def: "cDNA FLJ75371, highly similar to Homo sapiens regulator of G-protein signaling 9L mRNA" [UniProtKB:A8K3C0] synonym: "Regulator of G-protein signalling 9, isoform CRA_b" EXACT [UniProtKB:A8K3C0] xref: EMBL:BAF83224.1 xref: EMBL:EAW88998.1 xref: UniProtKB:A8K3C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019706 ! RGS9_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053963 name: A8K3J7_HUMAN def: "cDNA FLJ76546, highly similar to Homo sapiens cAMP responsive element modulator (CREM), transcript variant 7, mRNA" [UniProtKB:A8K3J7] xref: EMBL:BAF83301.1 xref: UniProtKB:A8K3J7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053964 name: A8K3M1_HUMAN def: "cDNA FLJ75656, highly similar to Homo sapiens msh homeo box homolog 1 (Drosophila) (MSX1), mRNA" [UniProtKB:A8K3M1] xref: EMBL:BAF83325.1 xref: UniProtKB:A8K3M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053965 name: A8K3P5_HUMAN def: "cDNA FLJ75189, highly similar to Homo sapiens zinc finger protein 585A, mRNA" [UniProtKB:A8K3P5] xref: EMBL:BAF83349.1 xref: UniProtKB:A8K3P5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053966 name: A8K4E4_HUMAN def: "cDNA FLJ75360, highly similar to Homo sapiens egf-like module containing, mucin-like, hormone receptor-like 3 (EMR3), transcript variant 1, mRNA" [UniProtKB:A8K4E4] xref: EMBL:BAF83598.1 xref: UniProtKB:A8K4E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0053967 name: A8K4X3_HUMAN def: "cDNA FLJ78443, highly similar to Homo sapiens tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A), mRNA" [UniProtKB:A8K4X3] xref: EMBL:BAF83777.1 xref: UniProtKB:A8K4X3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053968 name: A8K5A9_HUMAN def: "cDNA FLJ77532, highly similar to Homo sapiens zinc finger and SCAN domain containing 2 (ZSCAN2), transcript variant 1, mRNA" [UniProtKB:A8K5A9] xref: EMBL:BAF83913.1 xref: UniProtKB:A8K5A9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053969 name: A8K5K4_HUMAN def: "cDNA FLJ77543, highly similar to Homo sapiens nuclear receptor subfamily 2, group C, member 1 (NR2C1), transcript variant 1, mRNA" [UniProtKB:A8K5K4] xref: EMBL:BAF84008.1 xref: UniProtKB:A8K5K4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053970 name: A8K5N8_HUMAN def: "cDNA FLJ77257, highly similar to Homo sapiens zinc finger protein 43 (HTF6) (ZNF43), mRNA" [UniProtKB:A8K5N8] xref: EMBL:BAF84042.1 xref: UniProtKB:A8K5N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053971 name: A8K6A1_HUMAN def: "cDNA FLJ76412, highly similar to Homo sapiens cAMP responsive element modulator (CREM), transcript variant 10, mRNA" [UniProtKB:A8K6A1] xref: EMBL:BAF84255.1 xref: UniProtKB:A8K6A1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053972 name: A8K6J1_HUMAN def: "cDNA FLJ76491, highly similar to Homo sapiens zinc finger protein 544 (ZNF544), mRNA" [UniProtKB:A8K6J1] synonym: "Zinc finger protein 544, isoform CRA_a" EXACT [UniProtKB:A8K6J1] xref: EMBL:BAF84345.1 xref: EMBL:EAW72568.1 xref: UniProtKB:A8K6J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020807 ! ZNF544_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053973 name: A8K6W1_HUMAN def: "cDNA FLJ77470, highly similar to Homo sapiens egf-like module containing, mucin-like, hormone receptor-like 2 (EMR2), transcript variant 1, mRNA" [UniProtKB:A8K6W1] xref: EMBL:BAF84465.1 xref: UniProtKB:A8K6W1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0053974 name: A8K6Z7_HUMAN def: "cDNA FLJ78406" [UniProtKB:A8K6Z7] xref: EMBL:BAF84501.1 xref: UniProtKB:A8K6Z7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053975 name: A8K6Z9_HUMAN def: "cDNA FLJ77573" [UniProtKB:A8K6Z9] xref: EMBL:BAF84503.1 xref: UniProtKB:A8K6Z9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053976 name: A8K7H5_HUMAN def: "cDNA FLJ76721" [UniProtKB:A8K7H5] synonym: "Putative uncharacterized protein LOC125893" EXACT [UniProtKB:A8K7H5] xref: EMBL:BAF84679.1 xref: EMBL:EAW72106.1 xref: UniProtKB:A8K7H5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021044 ! LOC125893_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053977 name: A8K7K1_HUMAN def: "cDNA FLJ76675, highly similar to Homo sapiens RAS p21 protein activator 2 (RASA2), mRNA" [UniProtKB:A8K7K1] xref: EMBL:BAF84705.1 xref: UniProtKB:A8K7K1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053978 name: A8K8D4_HUMAN def: "cDNA FLJ77434, highly similar to Homo sapiens presenilin 2 (Alzheimer disease 4) (PSEN2), transcript variant 2, mRNA" [UniProtKB:A8K8D4] synonym: "Presenilin 2 (Alzheimer disease 4), isoform CRA_e" EXACT [UniProtKB:A8K8D4] xref: EMBL:BAF84988.1 xref: EMBL:EAW69800.1 xref: UniProtKB:A8K8D4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019531 ! PSEN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0053979 name: A8K8E1_HUMAN def: "cDNA FLJ77374" [UniProtKB:A8K8E1] synonym: "TBC1 domain family, member 15, isoform CRA_d" EXACT [UniProtKB:A8K8E1] xref: EMBL:BAF84995.1 xref: EMBL:EAW97276.1 xref: UniProtKB:A8K8E1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020160 ! TBC1D15_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0053980 name: A8K8M5_HUMAN def: "cDNA FLJ76938, highly similar to Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant 1, mRNA" [UniProtKB:A8K8M5] xref: EMBL:BAF85079.1 xref: UniProtKB:A8K8M5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053981 name: Z705D_HUMAN def: "Zinc finger protein 705D" [UniProtKB:A8K971] xref: EMBL:BAF85275.1 xref: UniProtKB:A8K971 xref: UniProtKB:A8MY01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020536 ! ZNF705D_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053982 name: A8K9D9_HUMAN def: "cDNA FLJ75135, highly similar to Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100), mRNA" [UniProtKB:A8K9D9] synonym: "Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (P49/p100), isoform CRA_a" EXACT [UniProtKB:A8K9D9] xref: EMBL:BAF85343.1 xref: EMBL:EAW49700.1 xref: UniProtKB:A8K9D9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005187 ! NFKB2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0053983 name: A8K9Z8_HUMAN def: "cDNA FLJ76193, highly similar to Homo sapiens Rho-related BTB domain containing 2 (RHOBTB2), mRNA" [UniProtKB:A8K9Z8] xref: EMBL:BAF85552.1 xref: UniProtKB:A8K9Z8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0053984 name: A8KAD2_HUMAN def: "cDNA FLJ77477, highly similar to Homo sapiens zinc finger protein 484 (ZNF484), transcript variant 2, mRNA" [UniProtKB:A8KAD2] xref: EMBL:BAF85686.1 xref: UniProtKB:A8KAD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053985 name: A8MPQ0_HUMAN def: "Putative uncharacterized protein ZNF320" [UniProtKB:A8MPQ0] xref: UniProtKB:A8MPQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020702 ! ZNF320_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053986 name: A8MPQ2_HUMAN def: "Putative uncharacterized protein CREM" [UniProtKB:A8MPQ2] xref: UniProtKB:A8MPQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017453 ! CREM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053987 name: A8MPQ3_HUMAN def: "Putative uncharacterized protein CNTNAP4" [UniProtKB:A8MPQ3] xref: UniProtKB:A8MPQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021045 ! CNTNAP4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053988 name: A8MPS8_HUMAN def: "Putative uncharacterized protein RAP1GAP" [UniProtKB:A8MPS8] xref: UniProtKB:A8MPS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053989 name: A8MPT8_HUMAN xref: UniProtKB:A8MPT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053990 name: A8MPU2_HUMAN def: "Putative uncharacterized protein ITGB1BP1 (Integrin beta 1 binding protein 1, isoform CRA_g)" [UniProtKB:A8MPU2] xref: EMBL:EAX00999.1 xref: UniProtKB:A8MPU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018341 ! ITGB1BP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0053991 name: A8MPW5_HUMAN xref: UniProtKB:A8MPW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0053992 name: A8MPY0_HUMAN def: "Uncharacterized protein ENSP00000347696" [UniProtKB:A8MPY0] xref: UniProtKB:A8MPY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053993 name: A8MQ07_HUMAN def: "Putative uncharacterized protein RAPGEF5" [UniProtKB:A8MQ07] xref: UniProtKB:A8MQ07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019788 ! RAPGEF5_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0053994 name: A8MQ12_HUMAN xref: UniProtKB:A8MQ12 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0053995 name: YS029_HUMAN def: "Putative zinc finger protein ENSP00000330994" [UniProtKB:A8MQ14] xref: UniProtKB:A8MQ14 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053996 name: A8MQ25_HUMAN def: "Uncharacterized protein ENSP00000331589" [UniProtKB:A8MQ25] xref: UniProtKB:A8MQ25 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053997 name: A8MQ74_HUMAN def: "Uncharacterized protein ENSP00000352990" [UniProtKB:A8MQ74] xref: UniProtKB:A8MQ74 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0053998 name: A8MQB2_HUMAN def: "Putative uncharacterized protein ENSP00000368994" [UniProtKB:A8MQB2] xref: UniProtKB:A8MQB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0053999 name: A8MQT8_HUMAN def: "Uncharacterized protein ENSP00000371678" [UniProtKB:A8MQT8] xref: UniProtKB:A8MQT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054000 name: A8MQU9_HUMAN def: "Putative uncharacterized protein PRKD1" [UniProtKB:A8MQU9] xref: UniProtKB:A8MQU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021046 ! PRKD1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054001 name: A8MQV3_HUMAN def: "Putative uncharacterized protein GPR114" [UniProtKB:A8MQV3] xref: UniProtKB:A8MQV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017957 ! GPR114_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054002 name: A8MRB2_HUMAN def: "Putative uncharacterized protein TFAM" [UniProtKB:A8MRB2] xref: UniProtKB:A8MRB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020244 ! TFAM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054003 name: A8MRT1_HUMAN def: "Putative uncharacterized protein SOX6" [UniProtKB:A8MRT1] xref: UniProtKB:A8MRT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019992 ! SOX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054004 name: A8MS86_HUMAN def: "Putative uncharacterized protein FNBP1" [UniProtKB:A8MS86] xref: UniProtKB:A8MS86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004651 ! FNBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054005 name: A8MS93_HUMAN def: "Putative uncharacterized protein ARHGEF10 (Rho guanine nucleotide exchange factor (GEF) 10, isoform CRA_e)" [UniProtKB:A8MS93] xref: EMBL:EAW51484.1 xref: UniProtKB:A8MS93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017019 ! ARHGEF10_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054006 name: A8MSI4_HUMAN xref: UniProtKB:A8MSI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054007 name: A8MSJ7_HUMAN def: "Putative uncharacterized protein RASA3" [UniProtKB:A8MSJ7] xref: UniProtKB:A8MSJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019623 ! RASA3_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054008 name: A8MSL1_HUMAN def: "Putative uncharacterized protein IRAK1" [UniProtKB:A8MSL1] xref: UniProtKB:A8MSL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018308 ! IRAK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054009 name: A8MSM5_HUMAN def: "Putative uncharacterized protein C20orf74" [UniProtKB:A8MSM5] xref: UniProtKB:A8MSM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017055 ! C20orf74_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054010 name: A8MSP2_HUMAN def: "Putative uncharacterized protein" [UniProtKB:A8MSP2] xref: EMBL:BAG54434.1 xref: EMBL:EAW89182.1 xref: UniProtKB:A8MSP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054011 name: ZN725_HUMAN def: "Putative zinc finger protein 725" [UniProtKB:A8MSQ6] xref: UniProtKB:A8MSQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020920 ! ZNF725_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054012 name: A8MST8_HUMAN def: "Putative uncharacterized protein NKIRAS2" [UniProtKB:A8MST8] xref: UniProtKB:A8MST8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018377 ! NKIRAS2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054013 name: A8MSV0_HUMAN def: "Putative uncharacterized protein RAB3C" [UniProtKB:A8MSV0] xref: UniProtKB:A8MSV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019595 ! RAB3C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054014 name: A8MSV4_HUMAN def: "Putative uncharacterized protein RAB24" [UniProtKB:A8MSV4] xref: UniProtKB:A8MSV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019581 ! RAB24_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054015 name: A8MSW6_HUMAN def: "Putative uncharacterized protein MLLT4 (Uncharacterized protein ENSP00000383625)" [UniProtKB:A8MSW6] xref: UniProtKB:A8MSW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004036 ! MLLT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054016 name: A8MSX5_HUMAN def: "Putative uncharacterized protein L3MBTL4" [UniProtKB:A8MSX5] xref: UniProtKB:A8MSX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018507 ! L3MBTL4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054017 name: A8MSY8_HUMAN def: "Putative uncharacterized protein ZNF658B" [UniProtKB:A8MSY8] xref: UniProtKB:A8MSY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020533 ! ZNF658B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054018 name: A8MSZ9_HUMAN xref: UniProtKB:A8MSZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054019 name: A8MT35_HUMAN def: "Putative uncharacterized protein HMOX2 (Heme oxygenase (Decycling) 2, isoform CRA_a)" [UniProtKB:A8MT35] xref: EMBL:EAW85299.1 xref: UniProtKB:A8MT35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004813 ! HMOX2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054020 name: A8MT47_HUMAN def: "Putative uncharacterized protein FCN2" [UniProtKB:A8MT47] xref: UniProtKB:A8MT47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017771 ! FCN2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054021 name: YL018_HUMAN def: "Putative zinc finger LOC440122" [UniProtKB:A8MT65] xref: UniProtKB:A8MT65 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054022 name: A8MT74_HUMAN def: "Putative uncharacterized protein LGR6" [UniProtKB:A8MT74] xref: UniProtKB:A8MT74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018483 ! LGR6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054023 name: A8MTC6_HUMAN def: "Putative uncharacterized protein RAB37 (RAB37, member RAS oncogene family, isoform CRA_a)" [UniProtKB:A8MTC6] xref: EMBL:EAW89177.1 xref: UniProtKB:A8MTC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054024 name: A8MTE1_HUMAN def: "Putative uncharacterized protein OR10W1" [UniProtKB:A8MTE1] xref: UniProtKB:A8MTE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018929 ! OR10W1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054025 name: A8MTE7_HUMAN def: "Putative uncharacterized protein ZNF605" [UniProtKB:A8MTE7] xref: UniProtKB:A8MTE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020850 ! ZNF605_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054026 name: A8MTG1_HUMAN def: "Putative uncharacterized protein ACTR3B (cDNA FLJ58769, highly similar to Homo sapiens ARP3 actin-related protein 3 homolog B (yeast) (ACTR3B), mRNA)" [UniProtKB:A8MTG1] xref: EMBL:BAG57575.1 xref: UniProtKB:A8MTG1 xref: UniProtKB:B4DFW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008904 ! ACTR3B_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0054027 name: A8MTI0_HUMAN def: "Putative uncharacterized protein ENSP00000381675" [UniProtKB:A8MTI0] xref: UniProtKB:A8MTI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054028 name: A8MTI5_HUMAN def: "Uncharacterized protein ENSP00000381777" [UniProtKB:A8MTI5] xref: UniProtKB:A8MTI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054029 name: A8MTK7_HUMAN def: "Putative uncharacterized protein ZNF614" [UniProtKB:A8MTK7] xref: UniProtKB:A8MTK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020855 ! ZNF614_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054030 name: A8MTL8_HUMAN def: "Putative uncharacterized protein L3MBTL4 (L(3)mbt-like 4 (Drosophila), isoform CRA_b)" [UniProtKB:A8MTL8] xref: EMBL:EAX01640.1 xref: UniProtKB:A8MTL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018507 ! L3MBTL4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054031 name: A8MTM7_HUMAN def: "Putative uncharacterized protein TBC1D3D" [UniProtKB:A8MTM7] xref: UniProtKB:A8MTM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020176 ! TBC1D3D_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054032 name: A8MTP8_HUMAN def: "Putative uncharacterized protein MS4A3" [UniProtKB:A8MTP8] xref: UniProtKB:A8MTP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018662 ! MS4A3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054033 name: NOTO_HUMAN def: "Homeobox protein notochord" [UniProtKB:A8MTQ0] xref: UniProtKB:A8MTQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022450 ! NOTO_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054034 name: A8MTT8_HUMAN def: "Putative uncharacterized protein ZNF286A" [UniProtKB:A8MTT8] xref: UniProtKB:A8MTT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020518 ! ZNF286A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054035 name: YS033_HUMAN def: "Zinc finger protein ENSP00000380285" [UniProtKB:A8MTY0] xref: UniProtKB:A8MTY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054036 name: A8MU01_HUMAN def: "Putative uncharacterized protein DNMBP" [UniProtKB:A8MU01] xref: UniProtKB:A8MU01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017598 ! DNMBP_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054037 name: A8MU07_HUMAN def: "Putative uncharacterized protein OR10G4" [UniProtKB:A8MU07] xref: UniProtKB:A8MU07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018909 ! OR10G4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054038 name: A8MU91_HUMAN def: "Uncharacterized protein ENSP00000383220" [UniProtKB:A8MU91] xref: UniProtKB:A8MU91 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054039 name: A8MUF8_HUMAN xref: UniProtKB:A8MUF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054040 name: A8MUG1_HUMAN def: "Putative uncharacterized protein ZNF420" [UniProtKB:A8MUG1] xref: UniProtKB:A8MUG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020742 ! ZNF420_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054041 name: A8MUH3_HUMAN def: "Putative uncharacterized protein CD3G" [UniProtKB:A8MUH3] xref: UniProtKB:A8MUH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017301 ! CD3G_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054042 name: A8MUM9_HUMAN def: "Putative uncharacterized protein OR52R1" [UniProtKB:A8MUM9] xref: UniProtKB:A8MUM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021047 ! OR52R1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054043 name: A8MUR1_HUMAN def: "Putative uncharacterized protein TMBIM6" [UniProtKB:A8MUR1] xref: UniProtKB:A8MUR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021048 ! TMBIM6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0054044 name: BCRL2_HUMAN def: "Putative BCR-like protein 2" [UniProtKB:A8MUR4] xref: UniProtKB:A8MUR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054045 name: A8MUS4_HUMAN def: "Putative uncharacterized protein OR52N5" [UniProtKB:A8MUS4] xref: UniProtKB:A8MUS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019021 ! OR52N5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054046 name: A8MUT4_HUMAN def: "Putative uncharacterized protein SGSM1" [UniProtKB:A8MUT4] xref: UniProtKB:A8MUT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019882 ! SGSM1_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054047 name: A8MUU7_HUMAN def: "cDNA FLJ30284 fis, clone BRACE2002812, highly similar to Homo sapiens RAB37, member RAS oncogene family (RAB37), transcript variant 3, mRNA" [UniProtKB:A8MUU7] synonym: "Putative uncharacterized protein RAB37" EXACT [UniProtKB:A8MUU7] synonym: "RAB37, member RAS oncogene family, isoform CRA_b" EXACT [UniProtKB:A8MUU7] xref: EMBL:BAG51433.1 xref: EMBL:EAW89178.1 xref: UniProtKB:A8MUU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054048 name: ZN735_HUMAN def: "Putative zinc finger protein 735" [UniProtKB:A8MUV8] xref: UniProtKB:A8MUV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022816 ! ZNF735_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054049 name: A8MUW4_HUMAN def: "Putative uncharacterized protein CELSR1" [UniProtKB:A8MUW4] xref: UniProtKB:A8MUW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017328 ! CELSR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054050 name: A8MUY8_HUMAN def: "Putative uncharacterized protein OR52K2" [UniProtKB:A8MUY8] xref: UniProtKB:A8MUY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019016 ! OR52K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054051 name: Z705G_HUMAN def: "Putative zinc finger protein 705G" [UniProtKB:A8MUZ8] xref: UniProtKB:A8MUZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022794 ! ZNF705G_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054052 name: A8MV06_HUMAN def: "Putative uncharacterized protein OR51A7" [UniProtKB:A8MV06] xref: UniProtKB:A8MV06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018982 ! OR51A7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054053 name: A8MV28_HUMAN def: "Putative uncharacterized protein TBC1D3G" [UniProtKB:A8MV28] xref: UniProtKB:A8MV28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020177 ! TBC1D3G_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054054 name: A8MV38_HUMAN def: "Putative uncharacterized protein ZNF230" [UniProtKB:A8MV38] xref: UniProtKB:A8MV38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020669 ! ZNF230_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054055 name: A8MV43_HUMAN def: "Putative uncharacterized protein ZNF425" [UniProtKB:A8MV43] xref: UniProtKB:A8MV43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020744 ! ZNF425_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054056 name: VGLL3_HUMAN def: "Transcription cofactor vestigial-like protein 3" [UniProtKB:A8MV65] synonym: "Vgl-3" EXACT [UniProtKB:A8MV65] xref: EMBL:AAH94780.1 xref: EMBL:EAW68870.1 xref: UniProtKB:A8MV65 xref: UniProtKB:Q504T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020447 ! VGLL3_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054057 name: A8MVA1_HUMAN def: "Putative uncharacterized protein ZNF701" [UniProtKB:A8MVA1] xref: UniProtKB:A8MVA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020907 ! ZNF701_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054058 name: A8MVF0_HUMAN def: "Uncharacterized protein ENSP00000382273" [UniProtKB:A8MVF0] xref: UniProtKB:A8MVF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054059 name: A8MVM0_HUMAN def: "Putative uncharacterized protein ZNF235" [UniProtKB:A8MVM0] xref: UniProtKB:A8MVM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020673 ! ZNF235_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054060 name: A8MVM2_HUMAN def: "Putative uncharacterized protein MFAP4 (Microfibrillar-associated protein 4, isoform CRA_a)" [UniProtKB:A8MVM2] xref: EMBL:EAW50888.1 xref: UniProtKB:A8MVM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018609 ! MFAP4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054061 name: A8MVM5_HUMAN def: "Putative uncharacterized protein OR4C3" [UniProtKB:A8MVM5] xref: UniProtKB:A8MVM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019135 ! OR4C3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054062 name: A8MVN0_HUMAN def: "Putative uncharacterized protein AKAP13" [UniProtKB:A8MVN0] xref: UniProtKB:A8MVN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016948 ! AKAP13_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054063 name: YA035_HUMAN def: "Putative zinc finger protein ENSP00000383733" [UniProtKB:A8MVP4] xref: UniProtKB:A8MVP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054064 name: A8MVP6_HUMAN def: "Putative uncharacterized protein CD3D" [UniProtKB:A8MVP6] xref: UniProtKB:A8MVP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017299 ! CD3D_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054065 name: Z705F_HUMAN def: "Zinc finger protein 705F" [UniProtKB:A8MVS1] xref: UniProtKB:A8MVS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020537 ! ZNF705F_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054066 name: A8MVV5_HUMAN def: "Putative uncharacterized protein OPN5" [UniProtKB:A8MVV5] xref: UniProtKB:A8MVV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019050 ! OPN5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054067 name: A8MVW4_HUMAN def: "Putative uncharacterized protein CNIH" [UniProtKB:A8MVW4] xref: UniProtKB:A8MVW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017404 ! CNIH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054068 name: YB045_HUMAN def: "DH and coiled-coil domain-containing protein ENSP00000381780" [UniProtKB:A8MVX0] xref: UniProtKB:A8MVX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054069 name: A8MVX5_HUMAN xref: UniProtKB:A8MVX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054070 name: A8MVZ3_HUMAN def: "Putative uncharacterized protein ENSP00000379699" [UniProtKB:A8MVZ3] xref: UniProtKB:A8MVZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054071 name: A8MW10_HUMAN def: "Putative uncharacterized protein ZNF713" [UniProtKB:A8MW10] xref: UniProtKB:A8MW10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020915 ! ZNF713_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054072 name: A8MW16_HUMAN def: "Putative uncharacterized protein PRDM2" [UniProtKB:A8MW16] xref: UniProtKB:A8MW16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019494 ! PRDM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054073 name: A8MW54_HUMAN def: "Putative uncharacterized protein TAAR5" [UniProtKB:A8MW54] xref: UniProtKB:A8MW54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020123 ! TAAR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054074 name: A8MW67_HUMAN def: "Putative uncharacterized protein ZNF320" [UniProtKB:A8MW67] xref: UniProtKB:A8MW67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020702 ! ZNF320_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054075 name: A8MW73_HUMAN def: "Putative uncharacterized protein ZFP14" [UniProtKB:A8MW73] xref: UniProtKB:A8MW73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020585 ! ZFP14_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054076 name: A8MW98_HUMAN def: "Putative uncharacterized protein ZNF382" [UniProtKB:A8MW98] xref: UniProtKB:A8MW98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020723 ! ZNF382_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054077 name: Z705H_HUMAN def: "Putative zinc finger protein 705H" [UniProtKB:A8MWA4] xref: UniProtKB:A8MWA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022795 ! ZNF705H_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054078 name: A8MWF9_HUMAN def: "Putative uncharacterized protein MEOX1" [UniProtKB:A8MWF9] xref: UniProtKB:A8MWF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018603 ! MEOX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054079 name: A8MWG5_HUMAN def: "Putative uncharacterized protein OR1N2" [UniProtKB:A8MWG5] xref: UniProtKB:A8MWG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021049 ! OR1N2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054080 name: A8MWI1_HUMAN def: "Putative uncharacterized protein GPR179" [UniProtKB:A8MWI1] xref: UniProtKB:A8MWI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021050 ! GPR179_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054081 name: A8MWR6_HUMAN def: "Putative uncharacterized protein TSC22D4 (HCG1770615, isoform CRA_b) (cDNA FLJ57331, highly similar to TSC22 domain family protein 4)" [UniProtKB:A8MWR6] xref: EMBL:BAG60060.1 xref: EMBL:EAW76529.1 xref: UniProtKB:A8MWR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005715 ! TSC22D4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054082 name: A8MWS2_HUMAN def: "Putative uncharacterized protein SPRED1" [UniProtKB:A8MWS2] xref: UniProtKB:A8MWS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020019 ! SPRED1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0054083 name: A8MWV7_HUMAN def: "Putative uncharacterized protein ZNF2" [UniProtKB:A8MWV7] xref: UniProtKB:A8MWV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020968 ! ZNF2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054084 name: A8MWY4_HUMAN def: "Putative uncharacterized protein PRDM2" [UniProtKB:A8MWY4] xref: UniProtKB:A8MWY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019494 ! PRDM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054085 name: A8MWY6_HUMAN def: "Putative uncharacterized protein ENSP00000377008" [UniProtKB:A8MWY6] xref: UniProtKB:A8MWY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054086 name: A8MX01_HUMAN def: "Putative uncharacterized protein OR6X1" [UniProtKB:A8MX01] xref: UniProtKB:A8MX01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019211 ! OR6X1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054087 name: A8MX14_HUMAN def: "Putative uncharacterized protein NRL" [UniProtKB:A8MX14] xref: UniProtKB:A8MX14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018870 ! NRL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054088 name: A8MX22_HUMAN def: "Putative uncharacterized protein PEG3" [UniProtKB:A8MX22] xref: UniProtKB:A8MX22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019361 ! PEG3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054089 name: A8MX31_HUMAN def: "Putative uncharacterized protein ZNF701" [UniProtKB:A8MX31] xref: UniProtKB:A8MX31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020907 ! ZNF701_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054090 name: A8MX39_HUMAN def: "Putative uncharacterized protein ERG" [UniProtKB:A8MX39] xref: UniProtKB:A8MX39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017727 ! ERG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054091 name: A8MX59_HUMAN def: "Putative uncharacterized protein CNTNAP4" [UniProtKB:A8MX59] xref: UniProtKB:A8MX59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021045 ! CNTNAP4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054092 name: A8MX67_HUMAN def: "Putative uncharacterized protein ZNF599" [UniProtKB:A8MX67] xref: UniProtKB:A8MX67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020848 ! ZNF599_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054093 name: A8MX88_HUMAN def: "Putative uncharacterized protein OR10G8" [UniProtKB:A8MX88] xref: UniProtKB:A8MX88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018912 ! OR10G8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054094 name: A8MXA6_HUMAN def: "Putative uncharacterized protein OR4A47" [UniProtKB:A8MXA6] xref: UniProtKB:A8MXA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018974 ! OR4A47_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054095 name: A8MXE9_HUMAN def: "Putative uncharacterized protein OR5V1" [UniProtKB:A8MXE9] xref: UniProtKB:A8MXE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019194 ! OR5V1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054096 name: A8MXF5_HUMAN def: "Putative uncharacterized protein RAB37" [UniProtKB:A8MXF5] xref: UniProtKB:A8MXF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054097 name: A8MXI2_HUMAN def: "Uncharacterized protein ENSP00000383678" [UniProtKB:A8MXI2] xref: UniProtKB:A8MXI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054098 name: A8MXI6_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:A8MXI6] synonym: "EC 2.7.10.1" EXACT [UniProtKB:A8MXI6] xref: UniProtKB:A8MXI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018885 ! NTRK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0054099 name: A8MXL3_HUMAN def: "Putative uncharacterized protein ARFGAP2" [UniProtKB:A8MXL3] xref: UniProtKB:A8MXL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017008 ! ARFGAP2_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0054100 name: A8MXL5_HUMAN def: "Putative uncharacterized protein OR51I2" [UniProtKB:A8MXL5] xref: UniProtKB:A8MXL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018995 ! OR51I2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054101 name: A8MXQ6_HUMAN def: "Putative uncharacterized protein TBC1D3E (Putative uncharacterized protein TBC1D3)" [UniProtKB:A8MXQ6] xref: UniProtKB:A8MXQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021032 ! TBC1D3E_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054102 name: A8MXS9_HUMAN xref: UniProtKB:A8MXS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054103 name: A8MXU2_HUMAN xref: UniProtKB:A8MXU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054104 name: A8MXU4_HUMAN def: "Putative uncharacterized protein OR51A7" [UniProtKB:A8MXU4] xref: UniProtKB:A8MXU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018982 ! OR51A7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054105 name: A8MXV8_HUMAN def: "Uncharacterized protein ENSP00000381951" [UniProtKB:A8MXV8] xref: UniProtKB:A8MXV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054107 name: A8MXY6_HUMAN def: "Putative uncharacterized protein ZNF791" [UniProtKB:A8MXY6] xref: UniProtKB:A8MXY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020944 ! ZNF791_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054108 name: A8MXZ2_HUMAN xref: UniProtKB:A8MXZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054109 name: A8MXZ4_HUMAN def: "Putative uncharacterized protein GPRC5C" [UniProtKB:A8MXZ4] xref: UniProtKB:A8MXZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017997 ! GPRC5C_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054110 name: A8MY01_HUMAN xref: UniProtKB:A8MY01 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054111 name: A8MY27_HUMAN def: "Putative uncharacterized protein OR8A1" [UniProtKB:A8MY27] xref: UniProtKB:A8MY27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021051 ! OR8A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054112 name: A8MY44_HUMAN xref: UniProtKB:A8MY44 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054113 name: A8MY63_HUMAN xref: UniProtKB:A8MY63 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054114 name: A8MY69_HUMAN def: "Putative uncharacterized protein ULK2" [UniProtKB:A8MY69] xref: UniProtKB:A8MY69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005882 ! ULK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054115 name: A8MY82_HUMAN def: "Putative uncharacterized protein ZNF57" [UniProtKB:A8MY82] xref: UniProtKB:A8MY82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020978 ! ZNF57_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054116 name: A8MY83_HUMAN def: "Putative uncharacterized protein OR52H1" [UniProtKB:A8MY83] xref: UniProtKB:A8MY83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021052 ! OR52H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054117 name: A8MY84_HUMAN def: "Putative uncharacterized protein ANGPTL4" [UniProtKB:A8MY84] xref: UniProtKB:A8MY84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016968 ! ANGPTL4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054118 name: A8MY87_HUMAN def: "Putative uncharacterized protein KSR1" [UniProtKB:A8MY87] xref: UniProtKB:A8MY87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018447 ! KSR1_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054119 name: A8MY91_HUMAN def: "Putative uncharacterized protein ZNF300 (Zinc finger protein 300, isoform CRA_e)" [UniProtKB:A8MY91] xref: EMBL:EAW61702.1 xref: UniProtKB:A8MY91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021053 ! ZNF300_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054120 name: A8MYD4_HUMAN def: "Putative uncharacterized protein SSX4B" [UniProtKB:A8MYD4] xref: UniProtKB:A8MYD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020052 ! SSX4B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054121 name: YA039_HUMAN def: "Putative zinc finger protein ENSP00000383832" [UniProtKB:A8MYF4] xref: UniProtKB:A8MYF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054122 name: A8MYG0_HUMAN def: "Putative uncharacterized protein ZNF765" [UniProtKB:A8MYG0] xref: UniProtKB:A8MYG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021054 ! ZNF765_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054123 name: A8MYJ4_HUMAN def: "Putative uncharacterized protein ZNF91" [UniProtKB:A8MYJ4] xref: UniProtKB:A8MYJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020994 ! ZNF91_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054124 name: A8MYJ5_HUMAN xref: UniProtKB:A8MYJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054125 name: A8MYM2_HUMAN def: "Uncharacterized protein ENSP00000381183" [UniProtKB:A8MYM2] xref: UniProtKB:A8MYM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054126 name: A8MYQ9_HUMAN def: "Putative uncharacterized protein RAB34" [UniProtKB:A8MYQ9] xref: UniProtKB:A8MYQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019589 ! RAB34_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054127 name: A8MYR5_HUMAN def: "Putative uncharacterized protein PRKD1" [UniProtKB:A8MYR5] xref: UniProtKB:A8MYR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021046 ! PRKD1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054128 name: A8MYS6_HUMAN def: "Uncharacterized protein ENSP00000379688" [UniProtKB:A8MYS6] xref: UniProtKB:A8MYS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054129 name: A8MYT0_HUMAN def: "Putative uncharacterized protein RAB37" [UniProtKB:A8MYT0] xref: UniProtKB:A8MYT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054130 name: A8MYT4_HUMAN def: "Putative uncharacterized protein PIK3C3" [UniProtKB:A8MYT4] xref: UniProtKB:A8MYT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019408 ! PIK3C3_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0054131 name: A8MYT8_HUMAN def: "Putative uncharacterized protein ZNF132" [UniProtKB:A8MYT8] xref: UniProtKB:A8MYT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020622 ! ZNF132_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054132 name: DCDCX_HUMAN def: "Putative doublecortin domain-containing protein ENSP00000382097" [UniProtKB:A8MYV0] xref: UniProtKB:A8MYV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054133 name: A8MYY5_HUMAN def: "Putative uncharacterized protein PTK2" [UniProtKB:A8MYY5] xref: UniProtKB:A8MYY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004606 ! PTK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: participates_in CCO:P0000714 ! signal complex assembly [Term] id: CCO:B0054134 name: A8MYY8_HUMAN def: "Putative uncharacterized protein ARPC3" [UniProtKB:A8MYY8] xref: UniProtKB:A8MYY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004102 ! ARPC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0054135 name: A8MZ16_HUMAN def: "Putative uncharacterized protein OR10G9" [UniProtKB:A8MZ16] xref: UniProtKB:A8MZ16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018913 ! OR10G9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054136 name: A8MZ46_HUMAN def: "Putative uncharacterized protein CD97" [UniProtKB:A8MZ46] xref: UniProtKB:A8MZ46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017316 ! CD97_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054137 name: LEUTX_HUMAN def: "Putative leucine-twenty homeobox" [UniProtKB:A8MZ59] xref: UniProtKB:A8MZ59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022369 ! LEUTX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054138 name: A8MZD7_HUMAN xref: UniProtKB:A8MZD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054139 name: A8MZF2_HUMAN def: "Uncharacterized protein ENSP00000381292" [UniProtKB:A8MZF2] xref: UniProtKB:A8MZF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054140 name: A8MZF4_HUMAN def: "Putative uncharacterized protein ZNF764" [UniProtKB:A8MZF4] xref: UniProtKB:A8MZF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005967 ! ZNF764_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054141 name: A8MZG4_HUMAN xref: UniProtKB:A8MZG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054142 name: A8MZG7_HUMAN def: "Putative uncharacterized protein OR6C4" [UniProtKB:A8MZG7] xref: UniProtKB:A8MZG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019201 ! OR6C4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054143 name: A8MZI4_HUMAN def: "Putative uncharacterized protein RAB37" [UniProtKB:A8MZI4] xref: UniProtKB:A8MZI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054144 name: A8MZL3_HUMAN def: "Putative uncharacterized protein MRGPRE (HCG2039161)" [UniProtKB:A8MZL3] xref: EMBL:EAX02547.1 xref: UniProtKB:A8MZL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021055 ! MRGPRE_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054145 name: A8VJE6_HUMAN def: "FBJ murine osteosarcoma viral oncogene-like B variant 2" [UniProtKB:A8VJE6] xref: EMBL:ABW34731.1 xref: UniProtKB:A8VJE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004652 ! FOSB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054146 name: A8VJG1_HUMAN def: "FBJ murine osteosarcoma viral oncogene-like B variant 6" [UniProtKB:A8VJG1] xref: EMBL:ABW34735.1 xref: UniProtKB:A8VJG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004652 ! FOSB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054147 name: A8W2L5_HUMAN def: "MutL-like 1 protein" [UniProtKB:A8W2L5] xref: EMBL:ABW69170.1 xref: UniProtKB:A8W2L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005100 ! MLH1_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0054148 name: A8WFQ8_HUMAN def: "Zinc finger protein 12" [UniProtKB:A8WFQ8] xref: EMBL:AAI54415.1 xref: UniProtKB:A8WFQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020958 ! ZNF12_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054149 name: A9C4B1_HUMAN def: "CCR4-NOT transcription complex, subunit 3" [UniProtKB:A9C4B1] xref: EMBL:CAP19115.1 xref: EMBL:CAQ09586.1 xref: UniProtKB:A9C4B1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017408 ! CNOT3_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054150 name: A9CQZ6_HUMAN def: "RAC/CDC42/Rho exchange factor" [UniProtKB:A9CQZ6] xref: EMBL:BAF94999.1 xref: UniProtKB:A9CQZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017914 ! GEFT_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054151 name: A9J6M5_HUMAN xref: UniProtKB:A9J6M5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0054152 name: A9UF01_HUMAN def: "BCR/ABL fusion protein isoform X8" [UniProtKB:A9UF01] xref: EMBL:ABX82707.1 xref: UniProtKB:A9UF01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008391 ! BCR/ABL fusion_human relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054153 name: A9UF05_HUMAN def: "BCR/ABL fusion protein isoform Y3" [UniProtKB:A9UF05] xref: EMBL:ABX82711.1 xref: UniProtKB:A9UF05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008391 ! BCR/ABL fusion_human relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054154 name: MI4GD_HUMAN def: "MIF4G domain-containing protein" [UniProtKB:A9UHW6] synonym: "hSLIP1" EXACT [UniProtKB:A9UHW6] synonym: "SLBP-interacting protein 1" EXACT [UniProtKB:A9UHW6] xref: EMBL:AAH33759.1 xref: EMBL:ABX83907.1 xref: EMBL:EAW89263.1 xref: UniProtKB:A9UHW6 xref: UniProtKB:Q8N4Q5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018614 ! MIF4GD_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0054155 name: A9UJY7_HUMAN def: "MS4A15" [UniProtKB:A9UJY7] xref: EMBL:AAV91958.1 xref: UniProtKB:A9UJY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018544 ! MS4A15_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054156 name: A9UL17_HUMAN def: "Ets-1 transcript variant ets-1 delta(III-VI)" [UniProtKB:A9UL17] xref: EMBL:AAY19514.1 xref: UniProtKB:A9UL17 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054157 name: A9YD18_HUMAN def: "BCR/ABL e8a2 fusion protein" [UniProtKB:A9YD18] xref: EMBL:ABX79391.1 xref: UniProtKB:A9YD18 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054158 name: A9Z1W3_HUMAN xref: UniProtKB:A9Z1W3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054159 name: A9Z1Z2_HUMAN def: "Regulatory factor X, 3 (Influences HLA class II expression)" [UniProtKB:A9Z1Z2] xref: EMBL:CAI13402.1 xref: EMBL:CAI41214.1 xref: UniProtKB:A9Z1Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019685 ! RFX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054160 name: B0AZN8_HUMAN def: "cDNA, FLJ79478, highly similar to Homo sapiens zinc finger protein 2 (ZNF2), transcript variant 1, mRNA (Zinc finger protein 2, isoform CRA_a)" [UniProtKB:B0AZN8] xref: EMBL:BAF98720.1 xref: EMBL:EAX10715.1 xref: UniProtKB:B0AZN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020968 ! ZNF2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054161 name: B0AZS9_HUMAN def: "cDNA, FLJ79519, highly similar to BCL2/adenovirus E1B 19 kDaprotein-interacting protein 3" [UniProtKB:B0AZS9] xref: EMBL:BAF98761.1 xref: UniProtKB:B0AZS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0054162 name: B0AZW0_HUMAN def: "cDNA, FLJ79550, moderately similar to Membrane-spanning 4-domains subfamily Amember 8B" [UniProtKB:B0AZW0] xref: EMBL:BAF98792.1 xref: UniProtKB:B0AZW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054163 name: B0KZ81_HUMAN def: "Protein kinase C delta VIII" [UniProtKB:B0KZ81] xref: EMBL:ABF68960.1 xref: UniProtKB:B0KZ81 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054164 name: B0LPH5_HUMAN def: "Protein kinase C, alpha" [UniProtKB:B0LPH5] xref: EMBL:ABY87554.1 xref: UniProtKB:B0LPH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004957 ! PRKCA_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054165 name: B0QYI1_HUMAN def: "TBC1 domain family, member 22A" [UniProtKB:B0QYI1] xref: EMBL:CAQ07921.1 xref: EMBL:CAQ09325.1 xref: EMBL:CAQ09486.1 xref: EMBL:CAQ09530.1 xref: EMBL:CAQ10968.1 xref: EMBL:CAQ11023.1 xref: UniProtKB:B0QYI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020156 ! TBC1D22A_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054166 name: B0QYI3_HUMAN def: "TBC1 domain family, member 22A (TBC1 domain family, member 22A, isoform CRA_c) (cDNA FLJ45751 fis, clone LYMPB2002344, highly similar to TBC1 domain family member 22A)" [UniProtKB:B0QYI3] xref: EMBL:BAG54543.1 xref: EMBL:CAQ07923.1 xref: EMBL:CAQ09327.1 xref: EMBL:CAQ09488.1 xref: EMBL:CAQ09532.1 xref: EMBL:CAQ10970.1 xref: EMBL:CAQ11025.1 xref: EMBL:EAW73445.1 xref: UniProtKB:B0QYI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020156 ! TBC1D22A_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054167 name: B0QYL8_HUMAN def: "Polymerase (RNA) II (DNA directed) polypeptide F" [UniProtKB:B0QYL8] xref: EMBL:CAQ06635.1 xref: UniProtKB:B0QYL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019777 ! POLR2F_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001068 ! RNA polymerase complex relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054168 name: B0QYL9_HUMAN def: "Polymerase (RNA) II (DNA directed) polypeptide F" [UniProtKB:B0QYL9] xref: EMBL:CAQ06636.1 xref: UniProtKB:B0QYL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019777 ! POLR2F_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001068 ! RNA polymerase complex relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054169 name: B0QYS8_HUMAN def: "Thyrotrophic embryonic factor (Thyrotrophic embryonic factor, isoform CRA_a) (cDNA FLJ34597 fis, clone KIDNE2009367, highly similar to THYROTROPH EMBRYONIC FACTOR)" [UniProtKB:B0QYS8] xref: EMBL:BAG52441.1 xref: EMBL:CAQ08872.1 xref: EMBL:EAW60430.1 xref: UniProtKB:B0QYS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020228 ! TEF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054170 name: B0QYT0_HUMAN def: "L(3)mbt-like 2 (Drosophila)" [UniProtKB:B0QYT0] xref: EMBL:CAQ09437.1 xref: UniProtKB:B0QYT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018505 ! L3MBTL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054171 name: B0QYU3_HUMAN def: "ESX homeobox 1 (Extraembryonic, spermatogenesis, homeobox 1 homolog) (Mouse)" [UniProtKB:B0QYU3] xref: EMBL:CAQ08095.1 xref: EMBL:EAX02755.1 xref: UniProtKB:B0QYU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017732 ! ESX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054172 name: B0QYV8_HUMAN def: "ADP-ribosylation factor GTPase activating protein 3" [UniProtKB:B0QYV8] xref: EMBL:CAQ08845.1 xref: UniProtKB:B0QYV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017009 ! ARFGAP3_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0054173 name: B0QYV9_HUMAN def: "ADP-ribosylation factor GTPase activating protein 3" [UniProtKB:B0QYV9] xref: EMBL:CAQ08846.1 xref: UniProtKB:B0QYV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017009 ! ARFGAP3_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0054174 name: B0QYW0_HUMAN xref: UniProtKB:B0QYW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054175 name: B0QYW7_HUMAN def: "Estrogen receptor 1" [UniProtKB:B0QYW7] xref: EMBL:CAQ09843.1 xref: EMBL:CAQ10019.1 xref: EMBL:CAQ10454.1 xref: UniProtKB:B0QYW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004590 ! ESR1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054176 name: B0QYX1_HUMAN def: "Peroxisome proliferator-activated receptor alpha" [UniProtKB:B0QYX1] xref: EMBL:CAQ09265.1 xref: UniProtKB:B0QYX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019479 ! PPARA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054177 name: B0QYX2_HUMAN def: "Peroxisome proliferator-activated receptor alpha" [UniProtKB:B0QYX2] xref: EMBL:CAQ09266.1 xref: UniProtKB:B0QYX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019479 ! PPARA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054178 name: B0QZ35_HUMAN def: "cDNA FLJ90324 fis, clone NT2RP2001817, highly similar to NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-)" [UniProtKB:B0QZ35] synonym: "Sirtuin (Silent mating type information regulation 2 homolog) 1 (S. cerevisiae)" EXACT [UniProtKB:B0QZ35] xref: EMBL:BAG52006.1 xref: EMBL:CAQ07293.1 xref: UniProtKB:B0QZ35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019912 ! SIRT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054179 name: B0QZ65_HUMAN def: "GTPase activating protein and VPS9 domains 1" [UniProtKB:B0QZ65] xref: EMBL:CAQ08738.1 xref: UniProtKB:B0QZ65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017864 ! GAPVD1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054180 name: B0QZ66_HUMAN def: "GTPase activating protein and VPS9 domains 1" [UniProtKB:B0QZ66] xref: EMBL:CAQ08739.1 xref: UniProtKB:B0QZ66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017864 ! GAPVD1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054181 name: B0QZ67_HUMAN def: "GTPase activating protein and VPS9 domains 1" [UniProtKB:B0QZ67] xref: EMBL:CAQ08740.1 xref: UniProtKB:B0QZ67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017864 ! GAPVD1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054182 name: B0QZD1_HUMAN def: "G-protein signaling modulator 2 (AGS3-like, C. elegans)" [UniProtKB:B0QZD1] xref: EMBL:CAQ09804.1 xref: UniProtKB:B0QZD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004724 ! GPSM2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054183 name: B0QZD3_HUMAN def: "Rho guanine exchange factor (GEF) 16" [UniProtKB:B0QZD3] xref: EMBL:CAQ07782.1 xref: UniProtKB:B0QZD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017022 ! ARHGEF16_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054184 name: B0QZD4_HUMAN def: "Rho guanine exchange factor (GEF) 16" [UniProtKB:B0QZD4] xref: EMBL:CAQ07783.1 xref: UniProtKB:B0QZD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017022 ! ARHGEF16_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054185 name: B0S882_HUMAN def: "Notch homolog 4 (Drosophila)" [UniProtKB:B0S882] xref: EMBL:CAQ06602.1 xref: UniProtKB:B0S882 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008797 ! NOTCH4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0054186 name: B0UY34_HUMAN def: "Olfactory receptor, family 12, subfamily D, member 2" [UniProtKB:B0UY34] xref: EMBL:CAQ10820.1 xref: UniProtKB:B0UY34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018938 ! OR12D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054187 name: B0UYX3_HUMAN def: "Tenascin XB" [UniProtKB:B0UYX3] xref: EMBL:CAQ09549.1 xref: EMBL:CAQ10916.1 xref: UniProtKB:B0UYX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020233 ! TNXB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054188 name: B0V046_HUMAN def: "Tenascin XB" [UniProtKB:B0V046] xref: EMBL:CAQ07654.1 xref: EMBL:CAQ08164.1 xref: EMBL:CAQ10260.1 xref: EMBL:CAQ11027.1 xref: UniProtKB:B0V046 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020233 ! TNXB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054189 name: B0V1T2_HUMAN def: "Olfactory receptor, family 2, subfamily J, member 1" [UniProtKB:B0V1T2] xref: EMBL:CAQ08043.1 xref: UniProtKB:B0V1T2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019100 ! OR2J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054190 name: B0V1T3_HUMAN def: "Olfactory receptor, family 2, subfamily J, member 3" [UniProtKB:B0V1T3] xref: EMBL:CAQ08044.1 xref: UniProtKB:B0V1T3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019102 ! OR2J3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054191 name: B0V1X5_HUMAN def: "Notch homolog 4 (Drosophila)" [UniProtKB:B0V1X5] xref: EMBL:CAQ09631.1 xref: UniProtKB:B0V1X5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008797 ! NOTCH4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0054192 name: B0V386_HUMAN def: "Novel protein" [UniProtKB:B0V386] xref: EMBL:CAQ09012.1 xref: EMBL:CAQ09347.1 xref: EMBL:CAQ09967.1 xref: UniProtKB:B0V386 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021056 ! XXbac-BCX360G3.2-001_human relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054193 name: B0V3I0_HUMAN def: "CCR4-NOT transcription complex, subunit 3" [UniProtKB:B0V3I0] xref: EMBL:CAQ06860.1 xref: EMBL:CAQ09585.1 xref: UniProtKB:B0V3I0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017408 ! CNOT3_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054194 name: B0YJ06_HUMAN def: "tRNA aspartic acid methyltransferase 1 variant 5" [UniProtKB:B0YJ06] xref: EMBL:ACA05982.1 xref: UniProtKB:B0YJ06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005826 ! TRDMT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0054195 name: B0YJ32_HUMAN def: "Laminin alpha-3 chain variant 1" [UniProtKB:B0YJ32] xref: EMBL:ACA06010.1 xref: UniProtKB:B0YJ32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021057 ! LAMA3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0054196 name: B0YJ33_HUMAN def: "Laminin alpha-3 chain variant 2" [UniProtKB:B0YJ33] xref: EMBL:ACA06011.1 xref: UniProtKB:B0YJ33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021057 ! LAMA3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0054197 name: B0YJ91_HUMAN def: "Rho-associated protein kinase 1" [UniProtKB:B0YJ91] xref: EMBL:ACA06069.1 xref: UniProtKB:B0YJ91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019765 ! ROCK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054198 name: B0ZBD2_HUMAN def: "Adrenergic, alpha-1A-, receptor variant 2" [UniProtKB:B0ZBD2] xref: EMBL:ACA05900.1 xref: UniProtKB:B0ZBD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011225 ! ADRA1A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001279 ! alpha1-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054199 name: B0ZBD3_HUMAN def: "Adrenergic, alpha-1A-, receptor variant 3" [UniProtKB:B0ZBD3] xref: EMBL:ACA05901.1 xref: UniProtKB:B0ZBD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011225 ! ADRA1A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001279 ! alpha1-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054200 name: B0ZBD8_HUMAN def: "Adrenergic, alpha-1A-, receptor variant 4" [UniProtKB:B0ZBD8] xref: EMBL:ACA05902.1 xref: UniProtKB:B0ZBD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011225 ! ADRA1A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001279 ! alpha1-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054201 name: B0ZBF7_HUMAN def: "Nuclear receptor subfamily 3, group C, member 2 variant 3" [UniProtKB:B0ZBF7] xref: EMBL:ACA05925.1 xref: UniProtKB:B0ZBF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018592 ! NR3C2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054202 name: B0ZBF8_HUMAN def: "Nuclear receptor subfamily 3, group C, member 2 variant 4" [UniProtKB:B0ZBF8] xref: EMBL:ACA05926.1 xref: UniProtKB:B0ZBF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018592 ! NR3C2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054203 name: B1AH57_HUMAN def: "RAB, member of RAS oncogene family-like 4" [UniProtKB:B1AH57] xref: EMBL:CAQ07603.1 xref: UniProtKB:B1AH57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019634 ! RABL4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054204 name: B1AH58_HUMAN def: "RAB, member of RAS oncogene family-like 4" [UniProtKB:B1AH58] xref: EMBL:CAQ07604.1 xref: UniProtKB:B1AH58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019634 ! RABL4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054205 name: B1AH77_HUMAN def: "Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2)" [UniProtKB:B1AH77] xref: EMBL:CAQ09480.1 xref: UniProtKB:B1AH77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019612 ! RAC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054206 name: B1AH78_HUMAN def: "Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2)" [UniProtKB:B1AH78] xref: EMBL:CAQ09481.1 xref: UniProtKB:B1AH78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019612 ! RAC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054207 name: B1AH80_HUMAN def: "Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2) (Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2), isoform CRA_c)" [UniProtKB:B1AH80] xref: EMBL:CAQ09483.1 xref: EMBL:EAW60151.1 xref: UniProtKB:B1AH80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019612 ! RAC2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054208 name: B1AH81_HUMAN def: "DEP domain containing 5" [UniProtKB:B1AH81] xref: EMBL:CAQ07958.1 xref: UniProtKB:B1AH81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017556 ! DEPDC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054209 name: B1AHA9_HUMAN def: "Minichromosome maintenance complex component 5" [UniProtKB:B1AHA9] xref: EMBL:CAQ08827.1 xref: UniProtKB:B1AHA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005040 ! MCM5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000634 ! DNA replication initiation [Term] id: CCO:B0054210 name: B1AHB8_HUMAN def: "Rho GTPase activating protein 8" [UniProtKB:B1AHB8] xref: EMBL:CAQ07742.1 xref: UniProtKB:B1AHB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005481 ! ARHGAP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054211 name: B1AHC3_HUMAN def: "Rho GTPase activating protein 8" [UniProtKB:B1AHC3] xref: EMBL:CAQ06715.1 xref: EMBL:CAQ07747.1 xref: EMBL:CAQ09258.1 xref: UniProtKB:B1AHC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005481 ! ARHGAP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054212 name: B1AHH1_HUMAN def: "X-box binding protein 1" [UniProtKB:B1AHH1] xref: EMBL:CAQ10751.1 xref: UniProtKB:B1AHH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020505 ! XBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054213 name: B1AHH2_HUMAN def: "X-box binding protein 1" [UniProtKB:B1AHH2] xref: EMBL:CAQ10752.1 xref: UniProtKB:B1AHH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020505 ! XBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054214 name: B1AHH4_HUMAN def: "Pleckstrin homology, Sec7 and coiled-coil domains 4" [UniProtKB:B1AHH4] xref: EMBL:CAQ07894.1 xref: UniProtKB:B1AHH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021058 ! PSCD4_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054215 name: B1AHH5_HUMAN def: "Pleckstrin homology, Sec7 and coiled-coil domains 4" [UniProtKB:B1AHH5] xref: EMBL:CAQ07895.1 xref: UniProtKB:B1AHH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021058 ! PSCD4_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054216 name: B1AHH6_HUMAN def: "Pleckstrin homology, Sec7 and coiled-coil domains 4" [UniProtKB:B1AHH6] xref: EMBL:CAQ07896.1 xref: UniProtKB:B1AHH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021058 ! PSCD4_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054217 name: B1AHH7_HUMAN def: "Pleckstrin homology, Sec7 and coiled-coil domains 4" [UniProtKB:B1AHH7] xref: EMBL:CAQ07897.1 xref: UniProtKB:B1AHH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021058 ! PSCD4_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054218 name: B1AHH8_HUMAN def: "Pleckstrin homology, Sec7 and coiled-coil domains 4" [UniProtKB:B1AHH8] xref: EMBL:CAQ07898.1 xref: UniProtKB:B1AHH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021058 ! PSCD4_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054219 name: B1AHI0_HUMAN def: "Pleckstrin homology, Sec7 and coiled-coil domains 4" [UniProtKB:B1AHI0] xref: EMBL:CAQ07900.1 xref: UniProtKB:B1AHI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021058 ! PSCD4_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054220 name: B1AJU4_HUMAN def: "Interferon regulatory factor 6" [UniProtKB:B1AJU4] xref: EMBL:CAI95692.1 xref: UniProtKB:B1AJU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011493 ! IRF6_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054221 name: B1AJV1_HUMAN def: "Zinc finger protein 81" [UniProtKB:B1AJV1] xref: EMBL:CAI39460.1 xref: EMBL:CAI42737.1 xref: UniProtKB:B1AJV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011768 ! ZNF81_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054222 name: B1AJV2_HUMAN def: "Zinc finger protein 81" [UniProtKB:B1AJV2] xref: EMBL:CAI39461.1 xref: EMBL:CAI42738.1 xref: EMBL:CAI42942.1 xref: UniProtKB:B1AJV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011768 ! ZNF81_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054223 name: B1AJZ6_HUMAN def: "Protein Wnt" [UniProtKB:B1AJZ6] xref: EMBL:CAI19850.1 xref: UniProtKB:B1AJZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020489 ! WNT4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054224 name: B1AK19_HUMAN def: "Prostaglandin E receptor 3 (Subtype EP3)" [UniProtKB:B1AK19] xref: EMBL:CAI20225.1 xref: UniProtKB:B1AK19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011598 ! PTGER3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054225 name: B1AK49_HUMAN def: "CD247 molecule (CD247 antigen, isoform CRA_c) (cDNA, FLJ94588, Homo sapiens CD3Z antigen, zeta polypeptide (TiT3 complex) (CD3Z), mRNA)" [UniProtKB:B1AK49] xref: EMBL:BAG36664.1 xref: EMBL:CAH69974.1 xref: EMBL:CAI21380.1 xref: EMBL:EAW90792.1 xref: UniProtKB:B1AK49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017302 ! CD247_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054226 name: B1AKD7_HUMAN def: "Androgen receptor (Dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)" [UniProtKB:B1AKD7] xref: EMBL:CAI40496.1 xref: EMBL:CAI40853.1 xref: EMBL:CAI43080.1 xref: EMBL:EAX05380.1 xref: UniProtKB:B1AKD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004058 ! AR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001235 ! androgen receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054227 name: B1AKN3_HUMAN def: "Arginine-glutamic acid dipeptide (RE) repeats (Arginine-glutamic acid dipeptide (RE) repeats, isoform CRA_b)" [UniProtKB:B1AKN3] xref: EMBL:CAH70517.1 xref: EMBL:CAI19209.1 xref: EMBL:EAW71599.1 xref: UniProtKB:B1AKN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014170 ! RERE_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054228 name: B1AKN5_HUMAN def: "Nuclear factor 1" [UniProtKB:B1AKN5] xref: EMBL:CAI13082.1 xref: EMBL:CAI23237.1 xref: UniProtKB:B1AKN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018772 ! NFIA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054229 name: B1AKN6_HUMAN def: "Nuclear factor 1" [UniProtKB:B1AKN6] xref: EMBL:CAI23238.1 xref: UniProtKB:B1AKN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018772 ! NFIA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054230 name: B1AKN7_HUMAN def: "Nuclear factor 1" [UniProtKB:B1AKN7] xref: EMBL:CAI13079.1 xref: EMBL:CAI23239.1 xref: UniProtKB:B1AKN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018772 ! NFIA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054231 name: B1AKN8_HUMAN def: "Nuclear factor 1" [UniProtKB:B1AKN8] xref: EMBL:CAI13083.1 xref: EMBL:CAI23242.1 xref: UniProtKB:B1AKN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018772 ! NFIA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054232 name: B1AKX7_HUMAN xref: UniProtKB:B1AKX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054233 name: B1AKZ3_HUMAN def: "cDNA FLJ38560 fis, clone HCHON2003642, highly similar to Astrocytic phosphoprotein PEA-15" [UniProtKB:B1AKZ3] synonym: "Phosphoprotein enriched in astrocytes 15" EXACT [UniProtKB:B1AKZ3] synonym: "Phosphoprotein enriched in astrocytes 15, isoform CRA_b" EXACT [UniProtKB:B1AKZ3] xref: EMBL:BAG53155.1 xref: EMBL:CAI15277.1 xref: EMBL:EAW52735.1 xref: UniProtKB:B1AKZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019358 ! PEA15_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0054234 name: B1AKZ5_HUMAN def: "Phosphoprotein enriched in astrocytes 15" [UniProtKB:B1AKZ5] xref: EMBL:CAI15278.1 xref: UniProtKB:B1AKZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019358 ! PEA15_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0054235 name: B1AL37_HUMAN def: "Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6, isoform CRA_b)" [UniProtKB:B1AL37] xref: EMBL:CAI42903.1 xref: EMBL:EAW88461.1 xref: UniProtKB:B1AL37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017016 ! ARHGEF6_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054236 name: B1AL40_HUMAN def: "Zinc finger protein 248" [UniProtKB:B1AL40] xref: EMBL:CAI12321.1 xref: UniProtKB:B1AL40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020677 ! ZNF248_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054237 name: B1AL89_HUMAN def: "cDNA FLJ33884 fis, clone CTONG2007293, highly similar to Zinc finger protein 484" [UniProtKB:B1AL89] synonym: "Zinc finger protein 484" EXACT [UniProtKB:B1AL89] synonym: "Zinc finger protein 484, isoform CRA_b" EXACT [UniProtKB:B1AL89] xref: EMBL:BAG52305.1 xref: EMBL:CAI41017.1 xref: EMBL:EAW62837.1 xref: UniProtKB:B1AL89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020770 ! ZNF484_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054238 name: B1ALC0_HUMAN def: "Actin-related protein 2/3 complex subunit 5" [UniProtKB:B1ALC0] xref: EMBL:CAI19481.1 xref: UniProtKB:B1ALC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017048 ! ARPC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0054239 name: B1ALK7_HUMAN def: "Rho guanine nucleotide exchange factor (GEF) 7" [UniProtKB:B1ALK7] xref: EMBL:CAI12463.1 xref: EMBL:CAI14672.1 xref: UniProtKB:B1ALK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017017 ! ARHGEF7_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054240 name: B1ALS0_HUMAN def: "Protein kinase, cGMP-dependent, type I" [UniProtKB:B1ALS0] xref: EMBL:CAI39627.1 xref: EMBL:CAI41306.1 xref: UniProtKB:B1ALS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018401 ! PRKG1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001059 ! cGMP-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation [Term] id: CCO:B0054241 name: B1ALU1_HUMAN def: "Latrophilin 2" [UniProtKB:B1ALU1] xref: EMBL:CAH71344.1 xref: EMBL:CAI22400.1 xref: UniProtKB:B1ALU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054242 name: B1ALU2_HUMAN def: "Latrophilin 2 (Latrophilin 2, isoform CRA_g)" [UniProtKB:B1ALU2] xref: EMBL:CAH71345.1 xref: EMBL:CAI22403.1 xref: EMBL:EAX06327.1 xref: UniProtKB:B1ALU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054243 name: B1ALU3_HUMAN def: "Latrophilin 2 (Latrophilin 2, isoform CRA_k)" [UniProtKB:B1ALU3] xref: EMBL:CAH71348.1 xref: EMBL:CAI22404.1 xref: EMBL:EAX06331.1 xref: UniProtKB:B1ALU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054244 name: B1ALU4_HUMAN def: "Latrophilin 2 (Latrophilin 2, isoform CRA_o)" [UniProtKB:B1ALU4] xref: EMBL:CAH71343.1 xref: EMBL:CAI22405.1 xref: EMBL:EAX06335.1 xref: UniProtKB:B1ALU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054245 name: B1ALU5_HUMAN def: "Latrophilin 2 (Latrophilin 2, isoform CRA_s)" [UniProtKB:B1ALU5] xref: EMBL:CAH71346.1 xref: EMBL:CAI22402.1 xref: EMBL:EAX06339.1 xref: UniProtKB:B1ALU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054246 name: B1ALU6_HUMAN def: "Latrophilin 2" [UniProtKB:B1ALU6] xref: EMBL:CAI22406.1 xref: UniProtKB:B1ALU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054247 name: B1ALX0_HUMAN def: "Tumor necrosis factor receptor superfamily, member 25" [UniProtKB:B1ALX0] xref: EMBL:CAI22152.1 xref: UniProtKB:B1ALX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020317 ! TNFRSF25_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054248 name: B1ALY0_HUMAN def: "A kinase (PRKA) anchor protein 2" [UniProtKB:B1ALY0] xref: EMBL:CAI10813.1 xref: EMBL:CAI12436.1 xref: EMBL:CAI13898.1 xref: EMBL:CAI39561.1 xref: UniProtKB:B1ALY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021059 ! AKAP2_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000822 ! regulation of cell shape [Term] id: CCO:B0054249 name: B1AM21_HUMAN def: "Guanine nucleotide binding protein (G protein), q polypeptide" [UniProtKB:B1AM21] xref: EMBL:CAI12197.1 xref: EMBL:CAI15998.1 xref: UniProtKB:B1AM21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014749 ! GNAQ_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054250 name: B1AM27_HUMAN def: "Unc-13 homolog B (C. elegans)" [UniProtKB:B1AM27] xref: EMBL:CAH71003.1 xref: EMBL:CAH71207.1 xref: EMBL:CAH73362.1 xref: UniProtKB:B1AM27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020408 ! UNC13B_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054251 name: B1AMA2_HUMAN def: "Contactin associated protein-like 3" [UniProtKB:B1AMA2] xref: EMBL:CAH70490.1 xref: EMBL:CAH72042.1 xref: UniProtKB:B1AMA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017419 ! CNTNAP3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054252 name: B1AMF5_HUMAN def: "Centaurin, beta 5" [UniProtKB:B1AMF5] xref: EMBL:CAI23264.1 xref: UniProtKB:B1AMF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008671 ! CENTB5_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0054253 name: B1AMR1_HUMAN def: "Teashirt family zinc finger 2" [UniProtKB:B1AMR1] xref: EMBL:CAM28286.1 xref: EMBL:CAM28321.1 xref: UniProtKB:B1AMR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008447 ! TSHZ2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054254 name: B1AMR3_HUMAN def: "Cdc42 guanine nucleotide exchange factor (GEF) 9 (cDNA FLJ59516, highly similar to Homo sapiens Cdc42 guanine nucleotide exchange factor (GEF) 9 (ARHGEF9), mRNA)" [UniProtKB:B1AMR3] xref: EMBL:BAG58186.1 xref: EMBL:CAI40402.1 xref: EMBL:CAI41196.1 xref: UniProtKB:B1AMR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011252 ! ARHGEF9_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054255 name: B1AMR4_HUMAN def: "Cdc42 guanine nucleotide exchange factor (GEF) 9" [UniProtKB:B1AMR4] xref: EMBL:CAI39552.1 xref: EMBL:CAI40403.1 xref: EMBL:CAI41197.1 xref: UniProtKB:B1AMR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011252 ! ARHGEF9_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054256 name: B1AMW4_HUMAN def: "5-hydroxytryptamine (Serotonin) receptor 2C (cDNA FLJ60572, highly similar to 5-hydroxytryptamine 2C receptor)" [UniProtKB:B1AMW4] xref: EMBL:BAG58583.1 xref: EMBL:CAH70192.1 xref: EMBL:CAI41334.1 xref: UniProtKB:B1AMW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011212 ! HTR2C_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054257 name: B1AMX3_HUMAN def: "Chromosome 9 open reading frame 86" [UniProtKB:B1AMX3] xref: EMBL:CAI12689.1 xref: UniProtKB:B1AMX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021060 ! C9orf86_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054258 name: B1AMX9_HUMAN def: "TNF receptor-associated factor 2" [UniProtKB:B1AMX9] xref: EMBL:CAI12704.1 xref: EMBL:CAI15105.1 xref: UniProtKB:B1AMX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005823 ! TRAF2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0054259 name: B1AN12_HUMAN def: "Cholinergic receptor, muscarinic 3" [UniProtKB:B1AN12] xref: EMBL:CAH72986.1 xref: UniProtKB:B1AN12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016900 ! CHRM3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001319 ! muscarinic acetylcholine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054260 name: B1ANN6_HUMAN def: "MAX interactor 1" [UniProtKB:B1ANN6] xref: EMBL:CAI15474.1 xref: UniProtKB:B1ANN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018686 ! MXI1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054261 name: B1ANN7_HUMAN def: "MAX interactor 1 (MAX interactor 1, isoform CRA_d)" [UniProtKB:B1ANN7] xref: EMBL:CAI15475.1 xref: EMBL:EAW49568.1 xref: UniProtKB:B1ANN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018686 ! MXI1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054262 name: B1ANN8_HUMAN def: "MAX interactor 1 (cDNA FLJ61042, highly similar to MAX-interacting protein 1)" [UniProtKB:B1ANN8] xref: EMBL:BAG64876.1 xref: EMBL:CAI15477.1 xref: UniProtKB:B1ANN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018686 ! MXI1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054263 name: B1ANN9_HUMAN def: "MAX interactor 1" [UniProtKB:B1ANN9] xref: EMBL:CAI15478.1 xref: UniProtKB:B1ANN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018686 ! MXI1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054264 name: B1ANP5_HUMAN def: "Regulatory factor X, 3 (Influences HLA class II expression)" [UniProtKB:B1ANP5] xref: EMBL:CAI13399.1 xref: UniProtKB:B1ANP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019685 ! RFX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054265 name: B1ANP6_HUMAN def: "Regulatory factor X, 3 (Influences HLA class II expression)" [UniProtKB:B1ANP6] xref: EMBL:CAI13400.1 xref: UniProtKB:B1ANP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019685 ! RFX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054266 name: B1ANP7_HUMAN def: "Regulatory factor X, 3 (Influences HLA class II expression)" [UniProtKB:B1ANP7] xref: EMBL:CAI13401.1 xref: UniProtKB:B1ANP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019685 ! RFX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054267 name: B1AP22_HUMAN def: "Presenilin 2 (Alzheimer disease 4) (Presenilin 2 (Alzheimer disease 4), isoform CRA_b)" [UniProtKB:B1AP22] xref: EMBL:CAH73111.1 xref: EMBL:EAW69797.1 xref: UniProtKB:B1AP22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019531 ! PSEN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054268 name: B1AP63_HUMAN def: "Lysophosphatidic acid receptor 1" [UniProtKB:B1AP63] xref: EMBL:CAI13009.1 xref: UniProtKB:B1AP63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021061 ! LPAR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054269 name: B1APE1_HUMAN def: "General transcription factor IIB" [UniProtKB:B1APE1] xref: EMBL:CAI41342.1 xref: UniProtKB:B1APE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020238 ! GTF2B_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054270 name: B1APE2_HUMAN def: "General transcription factor IIB" [UniProtKB:B1APE2] xref: EMBL:CAI41343.1 xref: UniProtKB:B1APE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020238 ! GTF2B_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054272 name: B1APH5_HUMAN xref: UniProtKB:B1APH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054273 name: B1APK8_HUMAN def: "Zinc finger protein 678" [UniProtKB:B1APK8] xref: EMBL:CAH71932.1 xref: EMBL:CAI21827.1 xref: UniProtKB:B1APK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020893 ! ZNF678_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054274 name: B1APT5_HUMAN def: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 3" [UniProtKB:B1APT5] xref: EMBL:CAH70706.1 xref: UniProtKB:B1APT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004035 ! MLLT3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054275 name: B1APT6_HUMAN def: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 3 (Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 3, isoform CRA_a)" [UniProtKB:B1APT6] xref: EMBL:CAH70707.1 xref: EMBL:EAW58630.1 xref: UniProtKB:B1APT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004035 ! MLLT3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054276 name: B1AQ29_HUMAN def: "Zinc finger protein 41" [UniProtKB:B1AQ29] xref: EMBL:CAI41592.1 xref: EMBL:CAI41628.1 xref: UniProtKB:B1AQ29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020974 ! ZNF41_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054277 name: B1AQP1_HUMAN def: "Upstream transcription factor 1 (Upstream transcription factor 1, isoform CRA_b)" [UniProtKB:B1AQP1] xref: EMBL:CAI15371.1 xref: EMBL:EAW52676.1 xref: UniProtKB:B1AQP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020421 ! USF1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054278 name: B1AWB3_HUMAN def: "G protein-coupled receptor 64" [UniProtKB:B1AWB3] xref: EMBL:CAI40668.1 xref: EMBL:CAI41675.1 xref: UniProtKB:B1AWB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054279 name: B1AWB4_HUMAN def: "G protein-coupled receptor 64" [UniProtKB:B1AWB4] xref: EMBL:CAI40670.1 xref: EMBL:CAI41677.1 xref: UniProtKB:B1AWB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054280 name: B1AWB6_HUMAN def: "G protein-coupled receptor 64" [UniProtKB:B1AWB6] xref: EMBL:CAI40669.1 xref: EMBL:CAI41676.1 xref: UniProtKB:B1AWB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054281 name: B1AWB7_HUMAN def: "G protein-coupled receptor 64" [UniProtKB:B1AWB7] xref: EMBL:CAI40671.1 xref: EMBL:CAI41678.1 xref: UniProtKB:B1AWB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007602 ! GPR64_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054282 name: B1B0A5_HUMAN def: "G protein-coupled receptor 173" [UniProtKB:B1B0A5] xref: EMBL:CAI42530.1 xref: EMBL:EAW93142.1 xref: UniProtKB:B1B0A5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017986 ! GPR173_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054283 name: B1B1F0_HUMAN def: "Opsin 1 (Cone pigments), long-wave-sensitive" [UniProtKB:B1B1F0] xref: EMBL:CAM28377.1 xref: UniProtKB:B1B1F0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019055 ! OPN1LW_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054284 name: B1B1I8_HUMAN def: "Paired box gene 6 (Aniridia, keratitis)" [UniProtKB:B1B1I8] xref: EMBL:CAG38083.1 xref: EMBL:CAG38359.1 xref: UniProtKB:B1B1I8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019309 ! PAX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054285 name: B1B1I9_HUMAN def: "Paired box gene 6 (Aniridia, keratitis)" [UniProtKB:B1B1I9] xref: EMBL:CAG38084.1 xref: EMBL:CAG38360.1 xref: UniProtKB:B1B1I9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019309 ! PAX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054286 name: B1B1J0_HUMAN def: "Paired box gene 6 (Aniridia, keratitis)" [UniProtKB:B1B1J0] xref: EMBL:CAG38085.1 xref: EMBL:CAG38361.1 xref: UniProtKB:B1B1J0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019309 ! PAX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054287 name: B1NLD0_HUMAN def: "Interleukin-1 receptor accessory protein transcript variant 3" [UniProtKB:B1NLD0] xref: EMBL:ABU90811.1 xref: UniProtKB:B1NLD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018255 ! IL1RAP_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054288 name: B1PRL2_HUMAN def: "EWS/FLI fusion protein" [UniProtKB:B1PRL2] xref: EMBL:ACA62796.1 xref: UniProtKB:B1PRL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054289 name: B1Q2X3_HUMAN def: "TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform" [UniProtKB:B1Q2X3] xref: EMBL:BAG15901.1 xref: UniProtKB:B1Q2X3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021062 ! N-TAF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054290 name: KITM_HUMAN def: "Thymidine kinase 2, mitochondrial precursor" [UniProtKB:O00142] synonym: "EC 2.7.1.21" EXACT [UniProtKB:O00142] synonym: "Mt-TK" EXACT [UniProtKB:O00142] xref: EMBL:AAC51167.1 xref: EMBL:CAA71523.3 xref: UniProtKB:O00142 xref: UniProtKB:O15238 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018405 ! TK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001155 ! thymidine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0054291 name: GPR25_HUMAN def: "Probable G-protein coupled receptor 25" [UniProtKB:O00155] xref: EMBL:AAB50155.2 xref: EMBL:AAI26387.1 xref: EMBL:AAI26389.1 xref: UniProtKB:A0AVJ5 xref: UniProtKB:O00155 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018011 ! GPR25_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054292 name: O00164_HUMAN def: "Ribosomal RNA upstream binding transcription factor" [UniProtKB:O00164] xref: EMBL:AAC51239.1 xref: UniProtKB:O00164 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020398 ! UBTF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054293 name: EYA2_HUMAN def: "Eyes absent homolog 2" [UniProtKB:O00167] synonym: "EC 3.1.3.48" EXACT [UniProtKB:O00167] xref: EMBL:AAB42065.1 xref: EMBL:AAB51120.1 xref: EMBL:AAH00289.2 xref: EMBL:AAH08803.1 xref: EMBL:AAH13882.2 xref: EMBL:CAA07815.1 xref: EMBL:CAA71310.1 xref: EMBL:CAI23166.1 xref: EMBL:CAI40099.1 xref: EMBL:CAI42150.1 xref: EMBL:CAI42536.1 xref: UniProtKB:O00167 xref: UniProtKB:Q5JSW8 xref: UniProtKB:Q96CV6 xref: UniProtKB:Q96H97 xref: UniProtKB:Q99503 xref: UniProtKB:Q99812 xref: UniProtKB:Q9BWF6 xref: UniProtKB:Q9H4S3 xref: UniProtKB:Q9H4S9 xref: UniProtKB:Q9NPZ4 xref: UniProtKB:Q9UIX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017747 ! EYA2_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015574 ! eya2-rbpms physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054294 name: O00172_HUMAN def: "Line-1 reverse transcriptase" [UniProtKB:O00172] xref: EMBL:AAC51337.1 xref: UniProtKB:O00172 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054295 name: CCL24_HUMAN def: "C-C motif chemokine 24 precursor" [UniProtKB:O00175] synonym: "CK-beta-6" EXACT [UniProtKB:O00175] synonym: "Eosinophil chemotactic protein 2" EXACT [UniProtKB:O00175] synonym: "Eotaxin-2" EXACT [UniProtKB:O00175] synonym: "MPIF-2" EXACT [UniProtKB:O00175] synonym: "Myeloid progenitor inhibitory factor 2" EXACT [UniProtKB:O00175] synonym: "Small-inducible cytokine A24" EXACT [UniProtKB:O00175] xref: EMBL:AAB51135.1 xref: EMBL:AAD15410.1 xref: EMBL:AAH69072.1 xref: EMBL:AAH69391.1 xref: EMBL:CAA11383.1 xref: UniProtKB:O00175 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017269 ! CCL24_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054296 name: LEG9_HUMAN def: "Galectin-9" [UniProtKB:O00182] synonym: "Ecalectin" EXACT [UniProtKB:O00182] synonym: "HOM-HD-21" EXACT [UniProtKB:O00182] xref: EMBL:BAA22166.1 xref: EMBL:BAA31542.1 xref: EMBL:BAB83624.1 xref: EMBL:BAB83625.1 xref: EMBL:CAA88922.1 xref: EMBL:CAB93851.1 xref: UniProtKB:O00182 xref: UniProtKB:O14532 xref: UniProtKB:O75028 xref: UniProtKB:Q9NQ58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018471 ! LGALS9_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001660 ! galactose binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054297 name: RB27B_HUMAN def: "Ras-related protein Rab-27B" [UniProtKB:O00194] synonym: "C25KG" EXACT [UniProtKB:O00194] xref: EMBL:AAC51194.2 xref: EMBL:AAH27474.1 xref: EMBL:AAK11243.1 xref: EMBL:AAM21102.1 xref: UniProtKB:O00194 xref: UniProtKB:Q9BZB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019635 ! RAB27B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069756 ! RB27B_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0069757 ! RB27B_HUMAN-Cysteine methyl ester218 [Term] id: CCO:B0054298 name: HRK_HUMAN def: "Activator of apoptosis harakiri" [UniProtKB:O00198] synonym: "BH3-interacting domain-containing protein 3" EXACT [UniProtKB:O00198] synonym: "Neuronal death protein DP5" EXACT [UniProtKB:O00198] xref: EMBL:AAC34931.1 xref: UniProtKB:O00198 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018162 ! HRK_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019274 ! hrk-bclw-1 direct interaction relationship: participates_in CCO:I0019466 ! bcl2l1-hrk direct interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000841 ! negative regulation of survival gene product expression relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0054299 name: AP3B1_HUMAN def: "AP-3 complex subunit beta-1" [UniProtKB:O00203] synonym: "Adapter-related protein complex 3 subunit beta-1" EXACT [UniProtKB:O00203] synonym: "Adaptor protein complex AP-3 beta-1 subunit" EXACT [UniProtKB:O00203] synonym: "Beta3A-adaptin" EXACT [UniProtKB:O00203] synonym: "Clathrin assembly protein complex 3 beta-1 large chain" EXACT [UniProtKB:O00203] xref: EMBL:AAB61638.1 xref: EMBL:AAD03778.1 xref: EMBL:AAG01739.1 xref: EMBL:AAH38444.1 xref: EMBL:CAD97982.1 xref: UniProtKB:O00203 xref: UniProtKB:O00580 xref: UniProtKB:Q7Z393 xref: UniProtKB:Q9HD66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016979 ! AP3B1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003040 ! positive regulation of NK T cell differentiation relationship: transforms_into CCO:B0065666 ! AP3B1_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0065667 ! AP3B1_HUMAN-Phosphoserine609 [Term] id: CCO:B0054300 name: RHOD_HUMAN def: "Rho-related GTP-binding protein RhoD precursor" [UniProtKB:O00212] synonym: "Rho-related protein HP1" EXACT [UniProtKB:O00212] synonym: "RhoHP1" EXACT [UniProtKB:O00212] xref: EMBL:AAH01338.1 xref: EMBL:AAM21120.1 xref: EMBL:BAA19652.1 xref: UniProtKB:O00212 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019731 ! RHOD_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0070010 ! RHOD_HUMAN-Cysteine methyl ester207 [Term] id: CCO:B0054301 name: TR10A_HUMAN def: "Tumor necrosis factor receptor superfamily member 10A precursor" [UniProtKB:O00220] synonym: "CD261 antigen" EXACT [UniProtKB:O00220] synonym: "Death receptor 4" EXACT [UniProtKB:O00220] synonym: "TNF-related apoptosis-inducing ligand receptor 1" EXACT [UniProtKB:O00220] synonym: "TRAIL receptor 1" EXACT [UniProtKB:O00220] synonym: "TRAIL-R1" EXACT [UniProtKB:O00220] xref: EMBL:AAC51226.1 xref: EMBL:AAH12866.1 xref: UniProtKB:O00220 xref: UniProtKB:Q96E62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020335 ! TNFRSF10A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017360 ! tnfsf10-tnfrs10a-1 physical interaction relationship: participates_in CCO:I0017361 ! tnfsf10-tnfrs10a-3 physical interaction relationship: participates_in CCO:I0017362 ! tnfsf10-tnfrs10b-4 physical interaction relationship: participates_in CCO:I0017498 ! tnfsf10-tnfrs10a-2 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: transforms_into CCO:B0071490 ! TR10A_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0071491 ! TR10A_HUMAN-Phosphoserine463 relationship: transforms_into CCO:B0071492 ! TR10A_HUMAN-Phosphoserine466 [Term] id: CCO:B0054302 name: SIRB1_HUMAN def: "Signal-regulatory protein beta-1 precursor" [UniProtKB:O00241] synonym: "CD172 antigen-like family member B" EXACT [UniProtKB:O00241] synonym: "CD172b antigen" EXACT [UniProtKB:O00241] synonym: "SIRP-beta-1" EXACT [UniProtKB:O00241] xref: EMBL:AAH25286.1 xref: EMBL:AAH75835.1 xref: EMBL:BAG36297.1 xref: EMBL:CAA71404.1 xref: EMBL:CAI16688.1 xref: EMBL:CAI21864.1 xref: UniProtKB:A6NLM2 xref: UniProtKB:B2R8V0 xref: UniProtKB:O00241 xref: UniProtKB:Q5TFR0 xref: UniProtKB:Q8TB12 xref: UniProtKB:Q9H1U5 xref: UniProtKB:Q9Y4V0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019910 ! SIRPB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054303 name: AGRP_HUMAN def: "Agouti-related protein precursor" [UniProtKB:O00253] xref: EMBL:AAB52240.1 xref: EMBL:AAB68621.1 xref: EMBL:AAI10444.1 xref: EMBL:AAK96256.1 xref: EMBL:AAL09457.1 xref: EMBL:ABC88473.1 xref: UniProtKB:O00253 xref: UniProtKB:O15459 xref: UniProtKB:Q2TBD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016932 ! AGRP_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0054304 name: CBX4_HUMAN def: "E3 SUMO-protein ligase CBX4" [UniProtKB:O00257] synonym: "Chromobox protein homolog 4" EXACT [UniProtKB:O00257] synonym: "hPc2" EXACT [UniProtKB:O00257] synonym: "Pc2" EXACT [UniProtKB:O00257] synonym: "Polycomb 2 homolog" EXACT [UniProtKB:O00257] xref: EMBL:AAB62734.1 xref: EMBL:AAB80718.1 xref: EMBL:AAH14967.1 xref: UniProtKB:O00257 xref: UniProtKB:Q96C04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017250 ! CBX4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020439 ! rnf2-cbx4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0064101 ! CBX4_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0064102 ! CBX4_HUMAN-Phosphothreonine495 [Term] id: CCO:B0054305 name: TAF4_HUMAN def: "Transcription initiation factor TFIID subunit 4" [UniProtKB:O00268] synonym: "RNA polymerase II TBP-associated factor subunit C" EXACT [UniProtKB:O00268] synonym: "TAF(II)135" EXACT [UniProtKB:O00268] synonym: "TAFII-130" EXACT [UniProtKB:O00268] synonym: "TAFII-135" EXACT [UniProtKB:O00268] synonym: "TAFII130" EXACT [UniProtKB:O00268] synonym: "TAFII135" EXACT [UniProtKB:O00268] synonym: "TBP-associated factor 4" EXACT [UniProtKB:O00268] synonym: "Transcription initiation factor TFIID 135 kDa subunit" EXACT [UniProtKB:O00268] xref: EMBL:AAC50901.1 xref: EMBL:AAT38111.1 xref: EMBL:CAA72189.1 xref: EMBL:CAI11045.1 xref: EMBL:CAI19182.1 xref: EMBL:EAW75407.1 xref: UniProtKB:A6NGD9 xref: UniProtKB:O00268 xref: UniProtKB:Q5TBP6 xref: UniProtKB:Q99721 xref: UniProtKB:Q9BR40 xref: UniProtKB:Q9BX42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020136 ! TAF4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:I0017793 ! taf12-taf4-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054306 name: GPR31_HUMAN def: "Probable G-protein coupled receptor 31" [UniProtKB:O00270] xref: EMBL:AAC51375.1 xref: EMBL:CAB99329.1 xref: UniProtKB:O00270 xref: UniProtKB:Q9NQ20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018014 ! GPR31_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054307 name: DFFA_HUMAN def: "DNA fragmentation factor subunit alpha" [UniProtKB:O00273] synonym: "DFF-45" EXACT [UniProtKB:O00273] synonym: "DNA fragmentation factor 45 kDa subunit" EXACT [UniProtKB:O00273] synonym: "ICAD" EXACT [UniProtKB:O00273] synonym: "Inhibitor of CAD" EXACT [UniProtKB:O00273] xref: EMBL:AAC51249.1 xref: EMBL:AAD32953.1 xref: EMBL:AAF02419.1 xref: EMBL:AAH00037.1 xref: EMBL:AAH07112.1 xref: EMBL:AAH07721.1 xref: EMBL:AAP35626.1 xref: UniProtKB:O00273 xref: UniProtKB:Q96I97 xref: UniProtKB:Q9Y6C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017562 ! DFFA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015189 ! dffa-ewsr1 physical interaction relationship: participates_in CCO:I0020671 ! strn4-dffa physical interaction relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0064742 ! DFFA_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0064743 ! DFFA_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0064744 ! DFFA_HUMAN-Phosphoserine315 [Term] id: CCO:B0054308 name: LFTY2_HUMAN def: "Left-right determination factor 2 precursor" [UniProtKB:O00292] synonym: "Endometrial bleeding-associated factor" EXACT [UniProtKB:O00292] synonym: "Left-right determination factor A" EXACT [UniProtKB:O00292] synonym: "Protein lefty-2" EXACT [UniProtKB:O00292] synonym: "Protein lefty-A" EXACT [UniProtKB:O00292] synonym: "TGF-beta-4" EXACT [UniProtKB:O00292] synonym: "Transforming growth factor beta-4" EXACT [UniProtKB:O00292] xref: EMBL:AAB53269.1 xref: EMBL:AAC32600.1 xref: EMBL:AAD48145.1 xref: EMBL:AAH35718.1 xref: EMBL:BAC11556.1 xref: EMBL:CAI21804.1 xref: UniProtKB:O00292 xref: UniProtKB:O75611 xref: UniProtKB:Q5TE89 xref: UniProtKB:Q8NBQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018478 ! LEFTY2_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001462 ! transforming growth factor beta receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0054309 name: CLIC1_HUMAN def: "Chloride intracellular channel protein 1" [UniProtKB:O00299] synonym: "Chloride channel ABP" EXACT [UniProtKB:O00299] synonym: "hRNCC" EXACT [UniProtKB:O00299] synonym: "NCC27" EXACT [UniProtKB:O00299] synonym: "Nuclear chloride ion channel 27" EXACT [UniProtKB:O00299] synonym: "Regulatory nuclear chloride ion channel protein" EXACT [UniProtKB:O00299] xref: EMBL:AAC25675.1 xref: EMBL:AAD18073.1 xref: EMBL:AAD20437.1 xref: EMBL:AAD26137.1 xref: EMBL:AAH64527.1 xref: EMBL:AAH95469.1 xref: EMBL:BAB63376.1 xref: EMBL:CAA61020.1 xref: EMBL:CAB46078.1 xref: EMBL:CAG46868.1 xref: EMBL:CAI18417.1 xref: UniProtKB:O00299 xref: UniProtKB:Q15089 xref: UniProtKB:Q502X1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017384 ! CLIC1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001515 ! voltage-gated chloride channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000460 ! brush border relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0018451 ! clic1-lsm1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064380 ! CLIC1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064381 ! CLIC1_HUMAN-Phosphotyrosine233 [Term] id: CCO:B0054310 name: TR11B_HUMAN def: "Tumor necrosis factor receptor superfamily member 11B precursor" [UniProtKB:O00300] synonym: "Osteoclastogenesis inhibitory factor" EXACT [UniProtKB:O00300] synonym: "Osteoprotegerin" EXACT [UniProtKB:O00300] xref: EMBL:AAB53709.1 xref: EMBL:AAF20168.1 xref: EMBL:AAH30155.1 xref: EMBL:AAR23265.1 xref: EMBL:BAA25910.1 xref: EMBL:BAA32076.1 xref: EMBL:BAD96875.1 xref: UniProtKB:O00300 xref: UniProtKB:O60236 xref: UniProtKB:Q53FX6 xref: UniProtKB:Q9UHP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020338 ! TNFRSF11B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054311 name: BMAL1_HUMAN def: "Aryl hydrocarbon receptor nuclear translocator-like protein 1" [UniProtKB:O00327] synonym: "Basic-helix-loop-helix-PAS protein MOP3" EXACT [UniProtKB:O00327] synonym: "bHLH-PAS protein JAP3" EXACT [UniProtKB:O00327] synonym: "Brain and muscle ARNT-like 1" EXACT [UniProtKB:O00327] synonym: "Member of PAS protein 3" EXACT [UniProtKB:O00327] xref: EMBL:AAB37248.1 xref: EMBL:AAC24353.1 xref: EMBL:AAC51213.1 xref: EMBL:AAH41129.2 xref: EMBL:BAA19935.1 xref: EMBL:BAA19936.1 xref: EMBL:BAA19937.1 xref: EMBL:BAA19938.1 xref: EMBL:BAA19939.1 xref: EMBL:BAA19968.1 xref: EMBL:EAW68513.1 xref: UniProtKB:O00313 xref: UniProtKB:O00314 xref: UniProtKB:O00315 xref: UniProtKB:O00316 xref: UniProtKB:O00317 xref: UniProtKB:O00327 xref: UniProtKB:Q8IUT4 xref: UniProtKB:Q99631 xref: UniProtKB:Q99649 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017165 ! ARNTL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0003602 ! aryl hydrocarbon receptor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0008202 ! Hsp90 protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0063941 ! BMAL1_HUMAN-N6-acetyllysine538 [Term] id: CCO:B0054312 name: O00360_HUMAN def: "Putative p150" [UniProtKB:O00360] xref: EMBL:AAC51261.1 xref: UniProtKB:O00360 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054313 name: O00362_HUMAN def: "Putative p150" [UniProtKB:O00362] xref: EMBL:AAC51263.1 xref: UniProtKB:O00362 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054314 name: O00363_HUMAN def: "Putative p150" [UniProtKB:O00363] xref: EMBL:AAC51264.1 xref: UniProtKB:O00363 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054315 name: O00366_HUMAN def: "Putative p150" [UniProtKB:O00366] xref: EMBL:AAC51267.1 xref: UniProtKB:O00366 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000099 ! DNA strand annealing activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication relationship: participates_in CCO:P0000842 ! caspase activation via cytochrome c relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0054316 name: P2Y10_HUMAN def: "Putative P2Y purinoceptor 10" [UniProtKB:O00398] synonym: "P2Y-like receptor" EXACT [UniProtKB:O00398] synonym: "P2Y10" EXACT [UniProtKB:O00398] xref: EMBL:AAB57836.1 xref: EMBL:AAH51875.2 xref: EMBL:AAH95498.1 xref: EMBL:AAP32293.1 xref: EMBL:CAB36889.1 xref: UniProtKB:O00398 xref: UniProtKB:Q4VBN7 xref: UniProtKB:Q86V16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019270 ! P2RY10_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054317 name: PDE2A_HUMAN def: "cGMP-dependent 3',5'-cyclic phosphodiesterase" [UniProtKB:O00408] synonym: "CGS-PDE" EXACT [UniProtKB:O00408] synonym: "cGSPDE" EXACT [UniProtKB:O00408] synonym: "Cyclic GMP-stimulated phosphodiesterase" EXACT [UniProtKB:O00408] synonym: "EC 3.1.4.17" EXACT [UniProtKB:O00408] xref: EMBL:AAC51320.1 xref: UniProtKB:O00408 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019335 ! PDE2A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000589 ! cGMP-stimulated cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054318 name: CCRL2_HUMAN def: "C-C chemokine receptor-like 2" [UniProtKB:O00421] synonym: "Chemokine receptor CCR11" EXACT [UniProtKB:O00421] synonym: "Chemokine receptor X" EXACT [UniProtKB:O00421] synonym: "Putative MCP-1 chemokine receptor" EXACT [UniProtKB:O00421] xref: EMBL:AAB57794.1 xref: EMBL:AAB82106.1 xref: EMBL:AAC34601.1 xref: EMBL:AAC34602.1 xref: EMBL:AAC39595.1 xref: EMBL:AAH25717.1 xref: EMBL:AAH71682.1 xref: EMBL:AAH96075.1 xref: EMBL:AAH96076.1 xref: EMBL:AAH99623.1 xref: EMBL:AAQ76789.1 xref: EMBL:CAC82985.1 xref: UniProtKB:O00421 xref: UniProtKB:O75307 xref: UniProtKB:Q4VBB0 xref: UniProtKB:Q6IPX0 xref: UniProtKB:Q96KP5 xref: UniProtKB:Q9UPG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017285 ! CCRL2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054319 name: IF2B3_HUMAN def: "Insulin-like growth factor 2 mRNA-binding protein 3" [UniProtKB:O00425] synonym: "hKOC" EXACT [UniProtKB:O00425] synonym: "IGF-II mRNA-binding protein 3" EXACT [UniProtKB:O00425] synonym: "IGF2 mRNA-binding protein 3" EXACT [UniProtKB:O00425] synonym: "IMP-3" EXACT [UniProtKB:O00425] synonym: "KH domain-containing protein overexpressed in cancer" EXACT [UniProtKB:O00425] synonym: "VICKZ family member 3" EXACT [UniProtKB:O00425] xref: EMBL:AAC35208.1 xref: EMBL:AAD09223.1 xref: EMBL:AAH51296.1 xref: EMBL:AAH65269.1 xref: EMBL:CAE45883.1 xref: EMBL:CAH56186.1 xref: UniProtKB:A0A4Z5 xref: UniProtKB:O00425 xref: UniProtKB:Q63HM0 xref: UniProtKB:Q6MZZ2 xref: UniProtKB:Q86VB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018222 ! IGF2BP3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0006094 ! translation regulator activity relationship: has_function CCO:F0007303 ! mRNA 5'-UTR binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:B0054320 name: DNM1L_HUMAN def: "Dynamin-1-like protein" [UniProtKB:O00429] synonym: "Dnm1p/Vps1p-like protein" EXACT [UniProtKB:O00429] synonym: "DVLP" EXACT [UniProtKB:O00429] synonym: "Dymple" EXACT [UniProtKB:O00429] synonym: "Dynamin family member proline-rich carboxyl-terminal domain less" EXACT [UniProtKB:O00429] synonym: "Dynamin-like protein" EXACT [UniProtKB:O00429] synonym: "Dynamin-like protein 4" EXACT [UniProtKB:O00429] synonym: "Dynamin-like protein IV" EXACT [UniProtKB:O00429] synonym: "Dynamin-related protein 1" EXACT [UniProtKB:O00429] synonym: "EC 3.6.5.5" EXACT [UniProtKB:O00429] synonym: "HdynIV" EXACT [UniProtKB:O00429] xref: EMBL:AAC23724.1 xref: EMBL:AAC35283.1 xref: EMBL:AAD39541.1 xref: EMBL:AAH00136.1 xref: EMBL:AAH24590.1 xref: EMBL:BAA22193.1 xref: UniProtKB:O00429 xref: UniProtKB:O14541 xref: UniProtKB:O60709 xref: UniProtKB:Q7L6B3 xref: UniProtKB:Q8TBT7 xref: UniProtKB:Q9BWM1 xref: UniProtKB:Q9Y5J2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017597 ! DNM1L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000380 ! cis-Golgi network relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020543 ! dnm1l-sirt3 physical interaction relationship: participates_in CCO:P0002253 ! mitochondrial fragmentation during apoptosis relationship: transforms_into CCO:B0064816 ! DNM1L_HUMAN-Phosphoserine616 [Term] id: CCO:B0054321 name: GFRA2_HUMAN def: "GDNF family receptor alpha-2 precursor" [UniProtKB:O00451] synonym: "GDNF receptor beta" EXACT [UniProtKB:O00451] synonym: "GDNFR-beta" EXACT [UniProtKB:O00451] synonym: "GFR-alpha-2" EXACT [UniProtKB:O00451] synonym: "Neurturin receptor alpha" EXACT [UniProtKB:O00451] synonym: "NRTNR-alpha" EXACT [UniProtKB:O00451] synonym: "NTNR-alpha" EXACT [UniProtKB:O00451] synonym: "RET ligand 2" EXACT [UniProtKB:O00451] synonym: "TGF-beta-related neurotrophic factor receptor 2" EXACT [UniProtKB:O00451] xref: EMBL:AAB61922.1 xref: EMBL:AAC51647.1 xref: EMBL:AAC52036.1 xref: EMBL:AAH41688.1 xref: EMBL:AAP88378.1 xref: UniProtKB:O00451 xref: UniProtKB:O15316 xref: UniProtKB:O15328 xref: UniProtKB:Q6GTR9 xref: UniProtKB:Q7Z5C2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017917 ! GFRA2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003058 ! glial cell line-derived neurotrophic factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0054322 name: LST1_HUMAN def: "Leukocyte-specific transcript 1 protein" [UniProtKB:O00453] synonym: "Protein B144" EXACT [UniProtKB:O00453] xref: EMBL:AAB57724.1 xref: EMBL:AAB86998.1 xref: EMBL:AAB86999.1 xref: EMBL:AAB87000.1 xref: EMBL:AAD18090.1 xref: EMBL:BAB63394.1 xref: EMBL:CAB59903.1 xref: EMBL:CAB59904.1 xref: EMBL:CAB59905.1 xref: EMBL:CAB59906.1 xref: EMBL:CAB60038.1 xref: EMBL:CAI17681.1 xref: EMBL:CAI17682.1 xref: EMBL:CAI17684.1 xref: EMBL:CAI17687.1 xref: EMBL:CAI18295.1 xref: EMBL:CAI18296.1 xref: EMBL:CAI18299.1 xref: EMBL:CAI18300.1 xref: EMBL:CAI18653.1 xref: EMBL:CAI18654.1 xref: EMBL:CAI18655.1 xref: EMBL:CAI18658.1 xref: EMBL:CAI41945.1 xref: EMBL:CAI41946.1 xref: EMBL:CAI41950.1 xref: EMBL:CAI41952.1 xref: EMBL:CAQ06947.1 xref: EMBL:CAQ07239.1 xref: EMBL:CAQ07723.1 xref: EMBL:CAQ10005.1 xref: EMBL:EAX03427.1 xref: UniProtKB:O00452 xref: UniProtKB:O00453 xref: UniProtKB:O00454 xref: UniProtKB:Q13669 xref: UniProtKB:Q5STA7 xref: UniProtKB:Q9UJR5 xref: UniProtKB:Q9UJR6 xref: UniProtKB:Q9UJR7 xref: UniProtKB:Q9UJR8 xref: UniProtKB:Q9UJS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018527 ! LST1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018469 ! lst1-q8wuq7 physical interaction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0002916 ! negative regulation of lymphocyte proliferation relationship: transforms_into CCO:B0067793 ! LST1_HUMAN-Phosphotyrosine88 [Term] id: CCO:B0054323 name: TRAF5_HUMAN def: "TNF receptor-associated factor 5" [UniProtKB:O00463] synonym: "RING finger protein 84" EXACT [UniProtKB:O00463] xref: EMBL:AAC51329.1 xref: EMBL:AAH29600.1 xref: EMBL:BAA25262.1 xref: UniProtKB:O00463 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020342 ! TRAF5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015923 ! atar-traf5-3 physical interaction relationship: participates_in CCO:I0015924 ! atar-traf5-4 physical interaction relationship: participates_in CCO:I0015928 ! rank-traf5 physical interaction relationship: participates_in CCO:I0017367 ! atar-traf5 physical interaction relationship: participates_in CCO:I0018033 ! atar-traf5-5 physical interaction relationship: participates_in CCO:I0018182 ! hvem-traf5 physical interaction relationship: participates_in CCO:I0019369 ! traf5-taj physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054324 name: ELL2_HUMAN def: "RNA polymerase II elongation factor ELL2" [UniProtKB:O00472] xref: EMBL:AAC51232.1 xref: EMBL:AAH28412.1 xref: UniProtKB:O00472 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017688 ! ELL2_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054325 name: NR5A2_HUMAN def: "Nuclear receptor subfamily 5 group A member 2" [UniProtKB:O00482] synonym: "Alpha-1-fetoprotein transcription factor" EXACT [UniProtKB:O00482] synonym: "B1-binding factor" EXACT [UniProtKB:O00482] synonym: "CYP7A promoter-binding factor" EXACT [UniProtKB:O00482] synonym: "hB1F" EXACT [UniProtKB:O00482] synonym: "Hepatocytic transcription factor" EXACT [UniProtKB:O00482] synonym: "Liver receptor homolog 1" EXACT [UniProtKB:O00482] synonym: "LRH-1" EXACT [UniProtKB:O00482] xref: EMBL:AAC78727.1 xref: EMBL:AAD03155.1 xref: EMBL:AAD26565.1 xref: EMBL:AAD37378.1 xref: EMBL:AAG17124.1 xref: EMBL:AAG17125.1 xref: UniProtKB:O00482 xref: UniProtKB:O95642 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018863 ! NR5A2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018848 ! edf1-nr5a2-1 physical interaction relationship: participates_in CCO:I0018850 ! edf1-nr5a2-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054326 name: O00485_HUMAN def: "Putative collagen homolog protein-a" [UniProtKB:O00485] xref: EMBL:AAB80687.1 xref: UniProtKB:O00485 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0054327 name: O00486_HUMAN def: "Putative collagen homolog protein-b" [UniProtKB:O00486] xref: EMBL:AAB80689.1 xref: UniProtKB:O00486 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0054328 name: ZN593_HUMAN def: "Zinc finger protein 593" [UniProtKB:O00488] synonym: "Zinc finger protein T86" EXACT [UniProtKB:O00488] xref: EMBL:AAH02580.1 xref: EMBL:AAH19267.1 xref: EMBL:BAA20369.1 xref: UniProtKB:O00488 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020843 ! ZNF593_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020640 ! rab1a-znf593 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054329 name: O00497_HUMAN def: "DNA mismatch repair protein" [UniProtKB:O00497] xref: EMBL:AAB58936.1 xref: UniProtKB:O00497 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021063 ! hMLH1_human relationship: has_function CCO:F0004953 ! guanine/thymine mispair binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0054330 name: KRIT1_HUMAN def: "Krev interaction trapped protein 1" [UniProtKB:O00522] synonym: "Cerebral cavernous malformations 1 protein" EXACT [UniProtKB:O00522] synonym: "Krev interaction trapped 1" EXACT [UniProtKB:O00522] xref: EMBL:AAB58582.1 xref: EMBL:AAC01535.1 xref: EMBL:AAG10220.2 xref: EMBL:AAG47774.1 xref: EMBL:AAH94684.1 xref: EMBL:AAH98442.1 xref: EMBL:AAM19465.1 xref: EMBL:AAQ94072.1 xref: EMBL:AAS07420.1 xref: EMBL:AAY25568.1 xref: EMBL:CAC17608.1 xref: UniProtKB:O00522 xref: UniProtKB:O43894 xref: UniProtKB:Q506L6 xref: UniProtKB:Q6U276 xref: UniProtKB:Q75N19 xref: UniProtKB:Q9H180 xref: UniProtKB:Q9H264 xref: UniProtKB:Q9HAX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018439 ! KRIT1_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054331 name: RCAS1_HUMAN def: "Receptor-binding cancer antigen expressed on SiSo cells" [UniProtKB:O00559] synonym: "Cancer-associated surface antigen RCAS1" EXACT [UniProtKB:O00559] synonym: "Estrogen receptor-binding fragment-associated gene 9 protein" EXACT [UniProtKB:O00559] xref: EMBL:AAB61617.1 xref: EMBL:AAH05249.1 xref: EMBL:AAH17729.1 xref: EMBL:AAH22506.1 xref: EMBL:BAA22572.1 xref: EMBL:CAG33265.1 xref: UniProtKB:O00559 xref: UniProtKB:Q6IB20 xref: UniProtKB:Q9BS76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019656 ! EBAG9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0069838 ! RCAS1_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0069839 ! RCAS1_HUMAN-Phosphothreonine41 relationship: transforms_into CCO:B0069840 ! RCAS1_HUMAN-Phosphotyrosine48 relationship: transforms_into CCO:B0069841 ! RCAS1_HUMAN-Phosphotyrosine94 [Term] id: CCO:B0054332 name: SDCB1_HUMAN def: "Syntenin-1" [UniProtKB:O00560] synonym: "MDA-9" EXACT [UniProtKB:O00560] synonym: "Melanoma differentiation-associated protein 9" EXACT [UniProtKB:O00560] synonym: "Pro-TGF-alpha cytoplasmic domain-interacting protein 18" EXACT [UniProtKB:O00560] synonym: "Scaffold protein Pbp1" EXACT [UniProtKB:O00560] synonym: "Syndecan-binding protein 1" EXACT [UniProtKB:O00560] synonym: "TACIP18" EXACT [UniProtKB:O00560] xref: EMBL:AAB51246.1 xref: EMBL:AAB97144.1 xref: EMBL:AAC52050.1 xref: EMBL:AAI13675.1 xref: EMBL:AAI13677.1 xref: UniProtKB:O00173 xref: UniProtKB:O00560 xref: UniProtKB:O43391 xref: UniProtKB:Q14CP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019857 ! SDCBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0070366 ! SDCB1_HUMAN-Phosphotyrosine46 relationship: transforms_into CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 [Term] id: CCO:B0054333 name: CXCR6_HUMAN def: "C-X-C chemokine receptor type 6" [UniProtKB:O00574] synonym: "CD186 antigen" EXACT [UniProtKB:O00574] synonym: "CDw186" EXACT [UniProtKB:O00574] synonym: "CXC-R6" EXACT [UniProtKB:O00574] synonym: "CXCR-6" EXACT [UniProtKB:O00574] synonym: "G-protein coupled receptor bonzo" EXACT [UniProtKB:O00574] synonym: "G-protein coupled receptor STRL33" EXACT [UniProtKB:O00574] xref: EMBL:AAB61456.1 xref: EMBL:AAB61457.1 xref: EMBL:AAB64221.1 xref: EMBL:AAG21918.1 xref: EMBL:AAH33584.1 xref: EMBL:AAP84356.1 xref: EMBL:CAA73698.1 xref: UniProtKB:O00574 xref: UniProtKB:O00575 xref: UniProtKB:Q9HCA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017502 ! CXCR6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054334 name: CCL21_HUMAN def: "C-C motif chemokine 21 precursor" [UniProtKB:O00585] synonym: "6Ckine" EXACT [UniProtKB:O00585] synonym: "Beta chemokine exodus-2" EXACT [UniProtKB:O00585] synonym: "Secondary lymphoid-tissue chemokine" EXACT [UniProtKB:O00585] synonym: "SLC" EXACT [UniProtKB:O00585] synonym: "Small-inducible cytokine A21" EXACT [UniProtKB:O00585] xref: EMBL:AAB86594.1 xref: EMBL:AAB91454.1 xref: EMBL:AAH27918.1 xref: EMBL:AAQ89246.1 xref: EMBL:BAA21817.1 xref: EMBL:CAA06653.1 xref: UniProtKB:O00585 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017266 ! CCL21_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0017526 ! ccl21-ubqln4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054335 name: CCBP2_HUMAN def: "Chemokine-binding protein 2" [UniProtKB:O00590] synonym: "C-C chemokine receptor D6" EXACT [UniProtKB:O00590] synonym: "Chemokine receptor CCR-10" EXACT [UniProtKB:O00590] synonym: "Chemokine receptor CCR-9" EXACT [UniProtKB:O00590] synonym: "Chemokine-binding protein D6" EXACT [UniProtKB:O00590] xref: EMBL:AAB97728.1 xref: EMBL:AAH08816.1 xref: EMBL:AAH11631.1 xref: EMBL:AAH20558.1 xref: EMBL:AAI01630.1 xref: EMBL:AAI12046.1 xref: EMBL:AAP20651.1 xref: EMBL:AAP35446.1 xref: EMBL:CAA73346.1 xref: UniProtKB:O00537 xref: UniProtKB:O00590 xref: UniProtKB:Q53YA1 xref: UniProtKB:Q86UN9 xref: UniProtKB:Q96A02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017256 ! CCBP2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054336 name: PODXL_HUMAN def: "Podocalyxin-like protein 1 precursor" [UniProtKB:O00592] xref: EMBL:AAB61574.1 xref: UniProtKB:O00592 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019465 ! PODXL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion [Term] id: CCO:B0054337 name: CYR61_HUMAN def: "Protein CYR61 precursor" [UniProtKB:O00622] synonym: "Cysteine-rich angiogenic inducer 61" EXACT [UniProtKB:O00622] synonym: "Insulin-like growth factor-binding protein 10" EXACT [UniProtKB:O00622] synonym: "Protein GIG1" EXACT [UniProtKB:O00622] xref: EMBL:AAB58319.1 xref: EMBL:AAB61240.1 xref: EMBL:AAB84227.1 xref: EMBL:AAG59863.1 xref: EMBL:AAH01271.1 xref: EMBL:AAH09199.1 xref: EMBL:AAH16952.1 xref: EMBL:AAR05446.1 xref: EMBL:CAA72167.1 xref: EMBL:CAA72802.1 xref: EMBL:CAB10848.1 xref: UniProtKB:O00622 xref: UniProtKB:O14934 xref: UniProtKB:O43775 xref: UniProtKB:Q9BZL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017513 ! CYR61_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054338 name: CCL22_HUMAN def: "C-C motif chemokine 22 precursor" [UniProtKB:O00626] synonym: "CC chemokine STCP-1" EXACT [UniProtKB:O00626] synonym: "Macrophage-derived chemokine" EXACT [UniProtKB:O00626] synonym: "MDC(1-69)" EXACT [UniProtKB:O00626] synonym: "Small-inducible cytokine A22" EXACT [UniProtKB:O00626] synonym: "Stimulated T-cell chemotactic protein 1" EXACT [UniProtKB:O00626] xref: EMBL:AAB53372.1 xref: EMBL:AAB58360.1 xref: EMBL:AAC24306.1 xref: EMBL:AAH27952.1 xref: UniProtKB:O00626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017267 ! CCL22_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054339 name: TRI38_HUMAN def: "Tripartite motif-containing protein 38" [UniProtKB:O00635] synonym: "RING finger protein 15" EXACT [UniProtKB:O00635] synonym: "Zinc finger protein RoRet" EXACT [UniProtKB:O00635] xref: EMBL:AAB53425.1 xref: EMBL:AAB82084.1 xref: EMBL:AAH26930.1 xref: UniProtKB:O00635 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020356 ! TRIM38_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054340 name: WN10B_HUMAN def: "Protein Wnt-10b precursor" [UniProtKB:O00744] synonym: "Wnt-12" EXACT [UniProtKB:O00744] xref: EMBL:AAB51685.1 xref: EMBL:AAC39549.1 xref: EMBL:AAH96353.1 xref: EMBL:AAH96354.1 xref: EMBL:AAH96356.1 xref: EMBL:BAB72181.1 xref: EMBL:CAA65769.1 xref: UniProtKB:O00744 xref: UniProtKB:O00747 xref: UniProtKB:Q4VAJ5 xref: UniProtKB:Q8WZ97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020479 ! WNT10B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054341 name: WNT7A_HUMAN def: "Protein Wnt-7a precursor" [UniProtKB:O00755] xref: EMBL:AAC51319.1 xref: EMBL:BAA82509.1 xref: UniProtKB:O00755 xref: UniProtKB:Q9Y560 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020493 ! WNT7A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:I0020675 ! strn4-wnt7a physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001388 ! regulation of axon diameter relationship: participates_in CCO:P0002945 ! regulation of neurogenesis relationship: participates_in CCO:P0003168 ! positive regulation of synaptogenesis [Term] id: CCO:B0054342 name: ACACB_HUMAN def: "Acetyl-CoA carboxylase 2" [UniProtKB:O00763] synonym: "ACC-beta" EXACT [UniProtKB:O00763] synonym: "EC 6.4.1.2" EXACT [UniProtKB:O00763] xref: EMBL:AAB58382.1 xref: EMBL:AAC50571.1 xref: EMBL:AAR37018.1 xref: EMBL:ABF48723.1 xref: EMBL:CAE01470.2 xref: EMBL:CAE01471.3 xref: UniProtKB:A6NK36 xref: UniProtKB:O00763 xref: UniProtKB:Q16852 xref: UniProtKB:Q1HEC1 xref: UniProtKB:Q6KE87 xref: UniProtKB:Q6KE89 xref: UniProtKB:Q6TY48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016879 ! ACACB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000474 ! acetyl-CoA carboxylase activity relationship: has_function CCO:F0000550 ! biotin carboxylase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002381 ! biotin binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation relationship: transforms_into CCO:B0065310 ! ACACB_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0065311 ! ACACB_HUMAN-Phosphoserine222 [Term] id: CCO:B0054343 name: SH2B2_HUMAN def: "SH2B adapter protein 2" [UniProtKB:O14492] synonym: "Adapter protein with pleckstrin homology and Src homology 2 domains" EXACT [UniProtKB:O14492] synonym: "SH2 and PH domain-containing adapter protein APS" EXACT [UniProtKB:O14492] xref: EMBL:BAA22514.1 xref: UniProtKB:A6ND74 xref: UniProtKB:O14492 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019887 ! SH2B2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002969 ! antigen receptor-mediated signaling pathway relationship: transforms_into CCO:B0070469 ! SH2B2_HUMAN-Phosphotyrosine629 [Term] id: CCO:B0054344 name: LPP1_HUMAN def: "Lipid phosphate phosphohydrolase 1" [UniProtKB:O14494] synonym: "EC 3.1.3.4" EXACT [UniProtKB:O14494] synonym: "PAP-2a" EXACT [UniProtKB:O14494] synonym: "PAP2-alpha" EXACT [UniProtKB:O14494] synonym: "PAP2a" EXACT [UniProtKB:O14494] synonym: "Phosphatidate phosphohydrolase type 2a" EXACT [UniProtKB:O14494] synonym: "Phosphatidic acid phosphatase 2a" EXACT [UniProtKB:O14494] xref: EMBL:AAC16032.1 xref: EMBL:AAC16033.1 xref: EMBL:AAC32041.1 xref: EMBL:AAH39847.1 xref: EMBL:AAI17134.1 xref: EMBL:BAA22593.1 xref: EMBL:CAC14588.1 xref: UniProtKB:O14494 xref: UniProtKB:O60457 xref: UniProtKB:O60463 xref: UniProtKB:Q17RZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018519 ! PPAP2A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001775 ! phosphatidate phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway [Term] id: CCO:B0054345 name: SOCS2_HUMAN def: "Suppressor of cytokine signaling 2" [UniProtKB:O14508] synonym: "CIS-2" EXACT [UniProtKB:O14508] synonym: "Cytokine-inducible SH2 protein 2" EXACT [UniProtKB:O14508] synonym: "SOCS-2" EXACT [UniProtKB:O14508] synonym: "SSI-2" EXACT [UniProtKB:O14508] synonym: "STAT-induced STAT inhibitor 2" EXACT [UniProtKB:O14508] xref: EMBL:AAC34745.1 xref: EMBL:AAC98896.1 xref: EMBL:AAD27710.1 xref: EMBL:AAH10399.1 xref: EMBL:BAA22429.1 xref: EMBL:BAA22536.1 xref: UniProtKB:O14508 xref: UniProtKB:O14542 xref: UniProtKB:O95102 xref: UniProtKB:Q9UKS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019973 ! SOCS2_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001433 ! growth hormone receptor binding relationship: has_function CCO:F0001450 ! prolactin receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001809 ! JAK pathway signal transduction adaptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015942 ! epor-socs2-4 physical interaction relationship: participates_in CCO:I0017745 ! epor-socs2-3 physical interaction relationship: participates_in CCO:I0018504 ! epor-socs2-5 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0054346 name: NRG2_HUMAN def: "Pro-neuregulin-2, membrane-bound isoform precursor" [UniProtKB:O14511] synonym: "Pro-NRG2" EXACT [UniProtKB:O14511] xref: EMBL:AAF28848.1 xref: EMBL:AAF28849.1 xref: EMBL:AAF28850.1 xref: EMBL:AAF28851.1 xref: EMBL:AAF28852.1 xref: EMBL:AAF28853.1 xref: EMBL:BAA23417.1 xref: UniProtKB:O14511 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018867 ! NRG2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068834 ! NRG2_HUMAN-Phosphoserine809 [Term] id: CCO:B0054347 name: SOCS7_HUMAN def: "Suppressor of cytokine signaling 7" [UniProtKB:O14512] synonym: "NAP-4" EXACT [UniProtKB:O14512] synonym: "Nck, Ash and phospholipase C gamma-binding protein" EXACT [UniProtKB:O14512] synonym: "Nck-associated protein 4" EXACT [UniProtKB:O14512] synonym: "SOCS-7" EXACT [UniProtKB:O14512] xref: EMBL:AAI28608.1 xref: EMBL:BAA22432.1 xref: UniProtKB:A2VCU2 xref: UniProtKB:O14512 xref: UniProtKB:Q0IJ63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019977 ! SOCS7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0054348 name: BAI1_HUMAN def: "Brain-specific angiogenesis inhibitor 1 precursor" [UniProtKB:O14514] xref: EMBL:BAA23647.1 xref: UniProtKB:O14514 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017119 ! BAI1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003198 ! brain-specific angiogenesis inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0063705 ! BAI1_HUMAN-Phosphoserine1278 relationship: transforms_into CCO:B0063706 ! BAI1_HUMAN-Phosphoserine1469 [Term] id: CCO:B0054349 name: SOCS6_HUMAN def: "Suppressor of cytokine signaling 6" [UniProtKB:O14544] synonym: "CIS-4" EXACT [UniProtKB:O14544] synonym: "Cytokine-inducible SH2 protein 4" EXACT [UniProtKB:O14544] synonym: "SOCS-4" EXACT [UniProtKB:O14544] synonym: "SOCS-6" EXACT [UniProtKB:O14544] synonym: "Suppressor of cytokine signaling 4" EXACT [UniProtKB:O14544] xref: EMBL:AAH20082.1 xref: EMBL:BAA22538.1 xref: EMBL:EAW66522.1 xref: UniProtKB:O14544 xref: UniProtKB:Q8WUM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019976 ! SOCS6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0070718 ! SOCS6_HUMAN-Phosphoserine419 [Term] id: CCO:B0054350 name: O14549_HUMAN def: "Osteoblast specific cysteine-rich protein" [UniProtKB:O14549] xref: EMBL:BAA22994.1 xref: UniProtKB:O14549 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0054351 name: G3PT_HUMAN def: "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific" [UniProtKB:O14556] synonym: "EC 1.2.1.12" EXACT [UniProtKB:O14556] synonym: "GAPDH-2" EXACT [UniProtKB:O14556] synonym: "Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2" EXACT [UniProtKB:O14556] synonym: "Spermatogenic glyceraldehyde-3-phosphate dehydrogenase" EXACT [UniProtKB:O14556] xref: EMBL:AAB64181.1 xref: EMBL:AAF87970.1 xref: EMBL:AAH36373.1 xref: EMBL:AAQ75383.1 xref: EMBL:CAA06501.1 xref: UniProtKB:O14556 xref: UniProtKB:O60823 xref: UniProtKB:Q6JTT9 xref: UniProtKB:Q9HCU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017857 ! GAPDHS_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000784 ! glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002279 ! glyceraldehyde-3-phosphate dehydrogenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000629 ! microtubule-based flagellum relationship: participates_in CCO:P0002569 ! positive regulation of glycolysis relationship: transforms_into CCO:B0066341 ! G3PT_HUMAN-Phosphothreonine318 [Term] id: CCO:B0054352 name: TCGAP_HUMAN def: "TC10/CDC42 GTPase-activating protein" [UniProtKB:O14559] synonym: "Sorting nexin-26" EXACT [UniProtKB:O14559] xref: EMBL:AAB81197.1 xref: EMBL:AAB81198.1 xref: EMBL:AAH14084.2 xref: EMBL:AAK97795.1 xref: EMBL:BAC86902.1 xref: EMBL:CAB70821.1 xref: UniProtKB:O14552 xref: UniProtKB:O14559 xref: UniProtKB:O14560 xref: UniProtKB:Q6ZSP6 xref: UniProtKB:Q96CP3 xref: UniProtKB:Q9NT23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020219 ! SNX26_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071285 ! TCGAP_HUMAN-Phosphoserine570 relationship: transforms_into CCO:B0071286 ! TCGAP_HUMAN-Phosphotyrosine1169 [Term] id: CCO:B0054353 name: OR7AH_HUMAN def: "Olfactory receptor 7A17" [UniProtKB:O14581] xref: EMBL:AAB82060.1 xref: EMBL:AAI01588.1 xref: EMBL:AAI17358.1 xref: EMBL:AAK95026.1 xref: EMBL:DAA04604.1 xref: UniProtKB:O14581 xref: UniProtKB:Q6IFQ6 xref: UniProtKB:Q96R98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019216 ! OR7A17_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054354 name: TPPC2_HUMAN def: "Trafficking protein particle complex subunit 2" [UniProtKB:O14582] synonym: "MBP-1-interacting protein 2A" EXACT [UniProtKB:O14582] synonym: "MIP-2A" EXACT [UniProtKB:O14582] synonym: "Sedlin" EXACT [UniProtKB:O14582] xref: EMBL:AAB80684.1 xref: EMBL:AAC14421.1 xref: EMBL:AAD49845.1 xref: EMBL:AAG02469.1 xref: EMBL:AAH08889.1 xref: EMBL:AAH16915.1 xref: EMBL:AAH32809.1 xref: EMBL:AAH52618.1 xref: UniProtKB:A6NEG0 xref: UniProtKB:O14582 xref: UniProtKB:Q9HD16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020330 ! TRAPPC2_human relationship: encoded_by CCO:G0020331 ! TRAPPC2P_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:I0015133 ! trappc2-zbed1x physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054355 name: RFXK_HUMAN def: "DNA-binding protein RFXANK" [UniProtKB:O14593] synonym: "Ankyrin repeat family A protein 1" EXACT [UniProtKB:O14593] synonym: "Regulatory factor X subunit B" EXACT [UniProtKB:O14593] synonym: "Regulatory factor X-associated ankyrin-containing protein" EXACT [UniProtKB:O14593] synonym: "RFX-B" EXACT [UniProtKB:O14593] xref: EMBL:AAB86654.1 xref: EMBL:AAC69883.1 xref: EMBL:AAD17972.1 xref: EMBL:AAD17973.1 xref: EMBL:AAD26991.1 xref: EMBL:AAI14564.1 xref: EMBL:CAG46996.1 xref: EMBL:EAW84795.1 xref: UniProtKB:O14593 xref: UniProtKB:O95839 xref: UniProtKB:Q6FGA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019689 ! RFXANK_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054356 name: GBGT2_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 precursor" [UniProtKB:O14610] synonym: "G gamma-C" EXACT [UniProtKB:O14610] synonym: "G-gamma-8" EXACT [UniProtKB:O14610] synonym: "G-gamma-9" EXACT [UniProtKB:O14610] xref: EMBL:AAB70039.1 xref: EMBL:AAH08663.1 xref: EMBL:AAK53384.1 xref: EMBL:AAM12590.1 xref: UniProtKB:O14610 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017891 ! GNGT2_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054357 name: BORG1_HUMAN def: "Cdc42 effector protein 2" [UniProtKB:O14613] synonym: "Binder of Rho GTPases 1" EXACT [UniProtKB:O14613] xref: EMBL:AAB81206.1 xref: EMBL:AAD16185.1 xref: EMBL:AAD48784.1 xref: EMBL:AAH22337.1 xref: EMBL:AAH75834.1 xref: EMBL:AAN39381.1 xref: EMBL:AAV38807.1 xref: UniProtKB:O14613 xref: UniProtKB:Q9UNS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017171 ! CDC42EP2_human relationship: has_function CCO:F0000130 ! opioid peptide activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003532 ! GTP-Rho binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001331 ! positive regulation of actin filament polymerization relationship: participates_in CCO:P0001391 ! positive regulation of pseudopodium formation relationship: participates_in CCO:P0001414 ! positive regulation of protein complex assembly [Term] id: CCO:B0054358 name: AP3D1_HUMAN def: "AP-3 complex subunit delta-1" [UniProtKB:O14617] synonym: "Adapter-related protein complex 3 subunit delta-1" EXACT [UniProtKB:O14617] synonym: "AP-3 complex subunit delta" EXACT [UniProtKB:O14617] synonym: "Delta-adaptin" EXACT [UniProtKB:O14617] xref: EMBL:AAC34212.1 xref: EMBL:AAC34214.1 xref: EMBL:AAC51761.1 xref: EMBL:AAD03777.1 xref: EMBL:AAG35473.1 xref: EMBL:AAH10065.1 xref: EMBL:BAD92041.1 xref: UniProtKB:O00202 xref: UniProtKB:O14617 xref: UniProtKB:O75262 xref: UniProtKB:Q59HF5 xref: UniProtKB:Q96G11 xref: UniProtKB:Q9H3C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016980 ! AP3D1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003040 ! positive regulation of NK T cell differentiation relationship: transforms_into CCO:B0065668 ! AP3D1_HUMAN-Phosphoserine632 relationship: transforms_into CCO:B0065669 ! AP3D1_HUMAN-Phosphoserine634 relationship: transforms_into CCO:B0065670 ! AP3D1_HUMAN-Phosphoserine636 relationship: transforms_into CCO:B0065671 ! AP3D1_HUMAN-Phosphoserine658 relationship: transforms_into CCO:B0065672 ! AP3D1_HUMAN-Phosphoserine759 relationship: transforms_into CCO:B0065673 ! AP3D1_HUMAN-Phosphothreonine762 relationship: transforms_into CCO:B0065674 ! AP3D1_HUMAN-Phosphoserine764 relationship: transforms_into CCO:B0065675 ! AP3D1_HUMAN-Phosphoserine788 relationship: transforms_into CCO:B0065676 ! AP3D1_HUMAN-Phosphoserine829 [Term] id: CCO:B0054359 name: CXL11_HUMAN def: "C-X-C motif chemokine 11 precursor" [UniProtKB:O14625] synonym: "Beta-R1" EXACT [UniProtKB:O14625] synonym: "H174" EXACT [UniProtKB:O14625] synonym: "I-TAC" EXACT [UniProtKB:O14625] synonym: "Interferon-gamma-inducible protein 9" EXACT [UniProtKB:O14625] synonym: "Interferon-inducible T-cell alpha chemoattractant" EXACT [UniProtKB:O14625] synonym: "IP-9" EXACT [UniProtKB:O14625] synonym: "Small-inducible cytokine B11" EXACT [UniProtKB:O14625] xref: EMBL:AAB17374.1 xref: EMBL:AAC39775.1 xref: EMBL:AAC51845.1 xref: EMBL:AAD10206.1 xref: EMBL:AAD38327.1 xref: EMBL:AAD38867.1 xref: EMBL:AAH05292.1 xref: EMBL:AAH12532.1 xref: EMBL:AAI10987.1 xref: EMBL:AAP35433.1 xref: EMBL:CAA75510.1 xref: EMBL:CAB51859.1 xref: UniProtKB:O14625 xref: UniProtKB:Q53YA3 xref: UniProtKB:Q92840 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017505 ! CXCL11_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054360 name: GP171_HUMAN def: "Probable G-protein coupled receptor 171" [UniProtKB:O14626] synonym: "G-protein coupled receptor H963" EXACT [UniProtKB:O14626] xref: EMBL:AAC51846.1 xref: EMBL:AAL47763.1 xref: UniProtKB:O14626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017985 ! GPR171_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054361 name: CDX4_HUMAN def: "Homeobox protein CDX-4" [UniProtKB:O14627] synonym: "Caudal-type homeobox protein 4" EXACT [UniProtKB:O14627] xref: EMBL:AAB66319.1 xref: EMBL:AAD01894.1 xref: EMBL:CAI40795.1 xref: UniProtKB:O14627 xref: UniProtKB:Q5JS20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017323 ! CDX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054362 name: ZN195_HUMAN def: "Zinc finger protein 195" [UniProtKB:O14628] xref: EMBL:AAB86596.1 xref: EMBL:BAF82788.1 xref: EMBL:EAX02548.1 xref: UniProtKB:A8K234 xref: UniProtKB:O14628 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020649 ! ZNF195_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054363 name: DVL1_HUMAN def: "Segment polarity protein dishevelled homolog DVL-1" [UniProtKB:O14640] synonym: "Dishevelled-1" EXACT [UniProtKB:O14640] synonym: "DSH homolog 1" EXACT [UniProtKB:O14640] xref: EMBL:AAB65242.1 xref: EMBL:CAI23185.1 xref: EMBL:CAI23187.1 xref: UniProtKB:O14640 xref: UniProtKB:Q5TA33 xref: UniProtKB:Q5TA35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017645 ! DVL1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020495 ! usp13-dvl1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054364 name: ADA10_HUMAN def: "ADAM 10 precursor" [UniProtKB:O14672] synonym: "A disintegrin and metalloproteinase domain 10" EXACT [UniProtKB:O14672] synonym: "CD156c antigen" EXACT [UniProtKB:O14672] synonym: "CDw156" EXACT [UniProtKB:O14672] synonym: "EC 3.4.24.81" EXACT [UniProtKB:O14672] synonym: "Kuzbanian protein homolog" EXACT [UniProtKB:O14672] synonym: "Mammalian disintegrin-metalloprotease" EXACT [UniProtKB:O14672] xref: EMBL:AAC51766.1 xref: EMBL:CAA88463.1 xref: UniProtKB:O14672 xref: UniProtKB:Q10742 xref: UniProtKB:Q92650 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016906 ! ADAM10_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000379 ! Golgi-associated vesicle relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0054365 name: EI24_HUMAN def: "Etoposide-induced protein 2.4 homolog" [UniProtKB:O14681] synonym: "p53-induced gene 8 protein" EXACT [UniProtKB:O14681] xref: EMBL:AAC39531.2 xref: EMBL:AAH02390.1 xref: EMBL:BAF84640.1 xref: EMBL:BAF98732.1 xref: EMBL:EAW67641.1 xref: UniProtKB:A8K7D6 xref: UniProtKB:O14681 xref: UniProtKB:Q9BUQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017669 ! EI24_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0064933 ! EI24_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0064934 ! EI24_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0064935 ! EI24_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0064936 ! EI24_HUMAN-Phosphoserine349 [Term] id: CCO:B0054366 name: P5I11_HUMAN def: "Tumor protein p53-inducible protein 11" [UniProtKB:O14683] synonym: "p53-induced gene 11 protein" EXACT [UniProtKB:O14683] xref: EMBL:AAC39533.1 xref: UniProtKB:O14683 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019279 ! TP53I11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0054367 name: PTGES_HUMAN def: "Prostaglandin E synthase" [UniProtKB:O14684] synonym: "EC 5.3.99.3" EXACT [UniProtKB:O14684] synonym: "MGST1-L1" EXACT [UniProtKB:O14684] synonym: "Microsomal glutathione S-transferase 1-like 1" EXACT [UniProtKB:O14684] synonym: "p53-induced gene 12 protein" EXACT [UniProtKB:O14684] xref: EMBL:AAB82299.1 xref: EMBL:AAC39534.1 xref: EMBL:AAH08280.1 xref: EMBL:CAB72099.1 xref: UniProtKB:O14684 xref: UniProtKB:O14900 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019540 ! PTGES_human relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0007573 ! prostaglandin-E synthase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054368 name: O14694_HUMAN def: "CCR5 receptor" [UniProtKB:O14694] xref: EMBL:AAB65704.1 xref: UniProtKB:O14694 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017280 ! CCR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054369 name: ZN197_HUMAN def: "Zinc finger protein 197" [UniProtKB:O14709] synonym: "Zinc finger protein with KRAB and SCAN domains 9" EXACT [UniProtKB:O14709] synonym: "ZnF20" EXACT [UniProtKB:O14709] xref: EMBL:AAB84385.1 xref: UniProtKB:O14709 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020650 ! ZNF197_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017480 ! disc1-znf197 physical interaction relationship: participates_in CCO:I0017481 ! mitap1-znf197 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054370 name: ITBP1_HUMAN def: "Integrin beta-1-binding protein 1" [UniProtKB:O14713] synonym: "ICAP-1" EXACT [UniProtKB:O14713] synonym: "Integrin cytoplasmic domain-associated protein 1" EXACT [UniProtKB:O14713] xref: EMBL:AAB88671.1 xref: EMBL:AAB88672.1 xref: EMBL:AAH12264.1 xref: UniProtKB:O14713 xref: UniProtKB:O14714 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018341 ! ITGB1BP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0054371 name: APAF_HUMAN def: "Apoptotic protease-activating factor 1" [UniProtKB:O14727] synonym: "Apaf-1" EXACT [UniProtKB:O14727] xref: EMBL:AAC51678.1 xref: EMBL:AAD34016.1 xref: EMBL:AAD38344.1 xref: EMBL:AAK28401.1 xref: EMBL:BAA24843.2 xref: EMBL:BAC77343.1 xref: EMBL:CAB55579.1 xref: EMBL:CAB55580.1 xref: EMBL:CAB55581.1 xref: EMBL:CAB55582.1 xref: EMBL:CAB55583.1 xref: EMBL:CAB55584.1 xref: EMBL:CAB55585.1 xref: EMBL:CAB55586.1 xref: EMBL:CAB55587.1 xref: EMBL:CAB55588.1 xref: EMBL:CAB56462.1 xref: EMBL:CAB65085.1 xref: EMBL:CAB65086.1 xref: EMBL:CAB65087.1 xref: UniProtKB:O14727 xref: UniProtKB:O43297 xref: UniProtKB:Q7Z438 xref: UniProtKB:Q9BXZ6 xref: UniProtKB:Q9UBZ5 xref: UniProtKB:Q9UGN8 xref: UniProtKB:Q9UGN9 xref: UniProtKB:Q9UGP0 xref: UniProtKB:Q9UJ58 xref: UniProtKB:Q9UJ59 xref: UniProtKB:Q9UJ60 xref: UniProtKB:Q9UJ61 xref: UniProtKB:Q9UJ62 xref: UniProtKB:Q9UJ63 xref: UniProtKB:Q9UJ64 xref: UniProtKB:Q9UJ65 xref: UniProtKB:Q9UJ66 xref: UniProtKB:Q9UJ67 xref: UniProtKB:Q9UNC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016983 ! APAF1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0017696 ! apaf1-casp9-1 physical interaction relationship: participates_in CCO:I0017697 ! apaf1-casp9-2 physical interaction relationship: participates_in CCO:I0017789 ! apaf1-casp9-5 direct interaction relationship: participates_in CCO:I0017871 ! casp9-apaf1-1 physical interaction relationship: participates_in CCO:I0017987 ! cycs-apaf1-1 physical interaction relationship: participates_in CCO:I0017988 ! cycs-apaf1-2 physical interaction relationship: participates_in CCO:I0018488 ! apaf1-casp9-4 physical interaction relationship: participates_in CCO:I0018616 ! apaf1-casp9-3 physical interaction relationship: participates_in CCO:P0000842 ! caspase activation via cytochrome c relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0065678 ! APAF_HUMAN-Phosphothreonine204 relationship: transforms_into CCO:B0065679 ! APAF_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0065680 ! APAF_HUMAN-Phosphoserine248 [Term] id: CCO:B0054372 name: TERT_HUMAN def: "Telomerase reverse transcriptase" [UniProtKB:O14746] synonym: "EC 2.7.7.49" EXACT [UniProtKB:O14746] synonym: "HEST2" EXACT [UniProtKB:O14746] synonym: "Telomerase catalytic subunit" EXACT [UniProtKB:O14746] synonym: "Telomerase-associated protein 2" EXACT [UniProtKB:O14746] synonym: "TP2" EXACT [UniProtKB:O14746] xref: EMBL:AAC51672.1 xref: EMBL:AAC51724.1 xref: EMBL:AAD30037.1 xref: EMBL:AAG23289.1 xref: EMBL:ABB72674.1 xref: EMBL:BAC11010.1 xref: EMBL:BAC11014.1 xref: UniProtKB:O14746 xref: UniProtKB:O14783 xref: UniProtKB:Q2XS35 xref: UniProtKB:Q8N6C3 xref: UniProtKB:Q8NG46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020234 ! TERT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication relationship: transforms_into CCO:B0071342 ! TERT_HUMAN-Phosphothreonine1113 relationship: transforms_into CCO:B0071343 ! TERT_HUMAN-Phosphoserine1125 [Term] id: CCO:B0054373 name: TR10B_HUMAN def: "Tumor necrosis factor receptor superfamily member 10B precursor" [UniProtKB:O14763] synonym: "CD262 antigen" EXACT [UniProtKB:O14763] synonym: "Death receptor 5" EXACT [UniProtKB:O14763] synonym: "TNF-related apoptosis-inducing ligand receptor 2" EXACT [UniProtKB:O14763] synonym: "TRAIL receptor 2" EXACT [UniProtKB:O14763] synonym: "TRAIL-R2" EXACT [UniProtKB:O14763] xref: EMBL:AAB67103.1 xref: EMBL:AAB67109.1 xref: EMBL:AAB70577.1 xref: EMBL:AAB70578.1 xref: EMBL:AAB71412.1 xref: EMBL:AAB71949.1 xref: EMBL:AAB81180.1 xref: EMBL:AAC01565.1 xref: EMBL:AAC51778.1 xref: EMBL:AAF07175.1 xref: EMBL:AAF75587.1 xref: EMBL:AAH01281.1 xref: EMBL:AAQ88644.1 xref: EMBL:BAA33723.1 xref: UniProtKB:O14720 xref: UniProtKB:O14763 xref: UniProtKB:O15508 xref: UniProtKB:O15517 xref: UniProtKB:O15531 xref: UniProtKB:Q6UXM8 xref: UniProtKB:Q9BVE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020336 ! TNFRSF10B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0006164 ! TRAIL binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015922 ! tnfsf10-tnfrs10b-1 physical interaction relationship: participates_in CCO:I0017360 ! tnfsf10-tnfrs10a-1 physical interaction relationship: participates_in CCO:I0017498 ! tnfsf10-tnfrs10a-2 physical interaction relationship: participates_in CCO:I0017813 ! tnfrsf10b-tnfsf10-1 direct interaction relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054374 name: ZN213_HUMAN def: "Zinc finger protein 213" [UniProtKB:O14771] synonym: "Putative transcription factor CR53" EXACT [UniProtKB:O14771] synonym: "Zinc finger protein with KRAB and SCAN domains 21" EXACT [UniProtKB:O14771] xref: EMBL:AAB70531.1 xref: EMBL:AAH07287.1 xref: UniProtKB:O14771 xref: UniProtKB:Q96IS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020656 ! ZNF213_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054375 name: TNF11_HUMAN def: "Tumor necrosis factor ligand superfamily member 11" [UniProtKB:O14788] synonym: "CD254 antigen" EXACT [UniProtKB:O14788] synonym: "ODF" EXACT [UniProtKB:O14788] synonym: "OPGL" EXACT [UniProtKB:O14788] synonym: "Osteoclast differentiation factor" EXACT [UniProtKB:O14788] synonym: "Osteoprotegerin ligand" EXACT [UniProtKB:O14788] synonym: "RANKL" EXACT [UniProtKB:O14788] synonym: "Receptor activator of nuclear factor kappa B ligand" EXACT [UniProtKB:O14788] synonym: "TNF-related activation-induced cytokine" EXACT [UniProtKB:O14788] synonym: "TRANCE" EXACT [UniProtKB:O14788] xref: EMBL:AAB86811.1 xref: EMBL:AAC39731.1 xref: EMBL:AAC51762.1 xref: EMBL:AAH74823.1 xref: EMBL:AAH74890.1 xref: EMBL:BAA90488.1 xref: EMBL:BAB71768.1 xref: EMBL:BAB79694.1 xref: EMBL:BAB79695.1 xref: UniProtKB:O14723 xref: UniProtKB:O14788 xref: UniProtKB:Q96Q17 xref: UniProtKB:Q9P2Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020298 ! TNFSF11_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002486 ! positive regulation of osteoclast differentiation [Term] id: CCO:B0054376 name: GDF8_HUMAN def: "Growth/differentiation factor 8 precursor" [UniProtKB:O14793] synonym: "GDF-8" EXACT [UniProtKB:O14793] synonym: "Myostatin" EXACT [UniProtKB:O14793] xref: EMBL:AAB86694.1 xref: EMBL:AAC96327.1 xref: EMBL:AAH74757.2 xref: UniProtKB:O14793 xref: UniProtKB:Q6B0H2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017907 ! MSTN_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0054377 name: UN13B_HUMAN def: "Protein unc-13 homolog B" [UniProtKB:O14795] synonym: "munc13" EXACT [UniProtKB:O14795] synonym: "Munc13-2" EXACT [UniProtKB:O14795] xref: EMBL:AAC19406.1 xref: EMBL:CAH71004.1 xref: EMBL:CAH71208.1 xref: EMBL:CAH73361.1 xref: EMBL:EAW58383.1 xref: UniProtKB:O14795 xref: UniProtKB:Q5VYM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020408 ! UNC13B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0071733 ! UN13B_HUMAN-Phosphothreonine605 [Term] id: CCO:B0054378 name: TAAR5_HUMAN def: "Trace amine-associated receptor 5" [UniProtKB:O14804] synonym: "Putative neurotransmitter receptor" EXACT [UniProtKB:O14804] xref: EMBL:AAC39581.1 xref: EMBL:AAH69171.1 xref: EMBL:AAH95541.1 xref: EMBL:AAI12210.1 xref: EMBL:AAI12212.1 xref: EMBL:AAV70123.1 xref: EMBL:CAH72100.1 xref: UniProtKB:O14804 xref: UniProtKB:Q2M1V1 xref: UniProtKB:Q4VBL1 xref: UniProtKB:Q5VUQ3 xref: UniProtKB:Q6NTA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020123 ! TAAR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054379 name: RASM_HUMAN def: "Ras-related protein M-Ras precursor" [UniProtKB:O14807] synonym: "Ras-related protein R-Ras3" EXACT [UniProtKB:O14807] xref: EMBL:AAC52085.1 xref: EMBL:AAD02287.1 xref: EMBL:AAM12632.1 xref: EMBL:AAV38860.1 xref: UniProtKB:O14807 xref: UniProtKB:Q86WX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019632 ! MRAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0069755 ! RASM_HUMAN-Cysteine methyl ester205 [Term] id: CCO:B0054380 name: PHX2A_HUMAN def: "Paired mesoderm homeobox protein 2A" [UniProtKB:O14813] synonym: "Aristaless homeobox protein homolog" EXACT [UniProtKB:O14813] synonym: "ARIX1 homeodomain protein" EXACT [UniProtKB:O14813] synonym: "Paired-like homeobox 2A" EXACT [UniProtKB:O14813] xref: EMBL:AAB82744.1 xref: EMBL:AAH41564.1 xref: UniProtKB:O14813 xref: UniProtKB:Q8IVZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019389 ! PHOX2A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054381 name: RGRF2_HUMAN def: "Ras-specific guanine nucleotide-releasing factor 2" [UniProtKB:O14827] synonym: "Guanine nucleotide-releasing factor 2" EXACT [UniProtKB:O14827] synonym: "Ras guanine nucleotide exchange factor 2" EXACT [UniProtKB:O14827] synonym: "Ras-GRF2" EXACT [UniProtKB:O14827] xref: EMBL:AAB80953.1 xref: EMBL:AAD55268.1 xref: EMBL:AAI26113.1 xref: EMBL:EAW95863.1 xref: UniProtKB:O14827 xref: UniProtKB:Q9UK56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019700 ! RASGRF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0069921 ! RGRF2_HUMAN-Phosphoserine737 [Term] id: CCO:B0054382 name: FFAR1_HUMAN def: "Free fatty acid receptor 1" [UniProtKB:O14842] synonym: "G-protein coupled receptor 40" EXACT [UniProtKB:O14842] xref: EMBL:AAB86710.1 xref: EMBL:AAH95536.1 xref: EMBL:AAI20945.1 xref: UniProtKB:O14842 xref: UniProtKB:Q0VAS2 xref: UniProtKB:Q4VBL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017781 ! FFAR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066173 ! FFAR1_HUMAN-Phosphotyrosine44 [Term] id: CCO:B0054383 name: FFAR3_HUMAN def: "Free fatty acid receptor 3" [UniProtKB:O14843] synonym: "G-protein coupled receptor 41" EXACT [UniProtKB:O14843] xref: EMBL:AAB86711.1 xref: EMBL:AAH35657.1 xref: EMBL:AAI13696.1 xref: UniProtKB:O14843 xref: UniProtKB:Q14CM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017783 ! FFAR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054384 name: BACH1_HUMAN def: "Transcription regulator protein BACH1" [UniProtKB:O14867] synonym: "BTB and CNC homolog 1" EXACT [UniProtKB:O14867] synonym: "HA2303" EXACT [UniProtKB:O14867] xref: EMBL:AAB84100.1 xref: EMBL:AAB84101.1 xref: EMBL:AAD14689.1 xref: EMBL:AAH63307.1 xref: EMBL:BAA24932.1 xref: EMBL:BAA95505.1 xref: EMBL:CAB90435.1 xref: UniProtKB:O14867 xref: UniProtKB:O43285 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017114 ! BACH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0063690 ! BACH1_HUMAN-Phosphoserine196 relationship: transforms_into CCO:B0063691 ! BACH1_HUMAN-Phosphoserine445 [Term] id: CCO:B0054385 name: BCKD_HUMAN def: "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor" [UniProtKB:O14874] synonym: "BCKD-kinase" EXACT [UniProtKB:O14874] synonym: "BCKDHKIN" EXACT [UniProtKB:O14874] synonym: "Branched-chain alpha-ketoacid dehydrogenase kinase" EXACT [UniProtKB:O14874] synonym: "EC 2.7.11.4" EXACT [UniProtKB:O14874] xref: EMBL:AAB82714.1 xref: EMBL:AAH07363.1 xref: UniProtKB:O14874 xref: UniProtKB:Q96IN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017137 ! BCKDK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0063788 ! BCKD_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0063789 ! BCKD_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0063790 ! BCKD_HUMAN-Phosphothreonine35 relationship: transforms_into CCO:B0063791 ! BCKD_HUMAN-Phosphoserine52 [Term] id: CCO:B0054386 name: MGST3_HUMAN def: "Microsomal glutathione S-transferase 3" [UniProtKB:O14880] synonym: "EC 2.5.1.18" EXACT [UniProtKB:O14880] synonym: "Microsomal GST-3" EXACT [UniProtKB:O14880] synonym: "Microsomal GST-III" EXACT [UniProtKB:O14880] xref: EMBL:AAB82609.1 xref: EMBL:AAH00505.1 xref: EMBL:AAH03034.1 xref: EMBL:AAH05964.1 xref: EMBL:AAQ81301.1 xref: EMBL:CAG29355.1 xref: EMBL:CAH74057.1 xref: UniProtKB:O14880 xref: UniProtKB:Q6ICN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018613 ! MGST3_human relationship: has_function CCO:F0000783 ! glutathione transferase activity relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020551 ! f10-mgst3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054387 name: KLF11_HUMAN def: "Krueppel-like factor 11" [UniProtKB:O14901] synonym: "TGFB-inducible early growth response protein 2" EXACT [UniProtKB:O14901] synonym: "TIEG-2" EXACT [UniProtKB:O14901] synonym: "Transforming growth factor-beta-inducible early growth response protein 2" EXACT [UniProtKB:O14901] xref: EMBL:AAC61880.1 xref: EMBL:AAF75793.1 xref: EMBL:AAH63286.1 xref: EMBL:AAH69383.1 xref: EMBL:AAH74922.1 xref: UniProtKB:O14901 xref: UniProtKB:Q9EPF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018409 ! KLF11_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018955 ! atxn1-klf11 physical interaction relationship: participates_in CCO:I0019000 ! atxn1-klf11-1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0054388 name: WNT9A_HUMAN def: "Protein Wnt-9a precursor" [UniProtKB:O14904] synonym: "Wnt-14" EXACT [UniProtKB:O14904] xref: EMBL:AAC39550.1 xref: EMBL:AAI11961.1 xref: EMBL:AAI13432.1 xref: EMBL:BAB61051.1 xref: EMBL:CAH71122.1 xref: EMBL:EAW69821.1 xref: UniProtKB:A6NLW2 xref: UniProtKB:O14904 xref: UniProtKB:Q2M2J3 xref: UniProtKB:Q5VWU0 xref: UniProtKB:Q96S50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020497 ! WNT9A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054389 name: WNT9B_HUMAN def: "Protein Wnt-9b precursor" [UniProtKB:O14905] synonym: "Wnt-14b" EXACT [UniProtKB:O14905] synonym: "Wnt-15" EXACT [UniProtKB:O14905] xref: EMBL:AAC39551.1 xref: EMBL:AAQ88584.1 xref: EMBL:BAB70499.1 xref: UniProtKB:O14905 xref: UniProtKB:Q6UXT4 xref: UniProtKB:Q96Q09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020498 ! WNT9B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054390 name: TX1B3_HUMAN def: "Tax1-binding protein 3" [UniProtKB:O14907] synonym: "Glutaminase-interacting protein 3" EXACT [UniProtKB:O14907] synonym: "Tax interaction protein 1" EXACT [UniProtKB:O14907] synonym: "TIP-1" EXACT [UniProtKB:O14907] xref: EMBL:AAB84248.2 xref: EMBL:AAF43104.1 xref: EMBL:AAG44368.1 xref: EMBL:AAH23980.1 xref: EMBL:AAK69111.1 xref: UniProtKB:O14907 xref: UniProtKB:Q7LCQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020387 ! TAX1BP3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020474 ! tcea2-tax1bp3 physical interaction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0054391 name: GIPC1_HUMAN def: "PDZ domain-containing protein GIPC1" [UniProtKB:O14908] synonym: "GAIP C-terminus-interacting protein" EXACT [UniProtKB:O14908] synonym: "RGS-GAIP-interacting protein" EXACT [UniProtKB:O14908] synonym: "RGS19-interacting protein 1" EXACT [UniProtKB:O14908] synonym: "Tax interaction protein 2" EXACT [UniProtKB:O14908] synonym: "TIP-2" EXACT [UniProtKB:O14908] xref: EMBL:AAB84249.1 xref: EMBL:AAC67548.1 xref: EMBL:AAH00410.1 xref: EMBL:AAH04226.2 xref: EMBL:AAH12810.1 xref: EMBL:AAH16169.1 xref: UniProtKB:O14908 xref: UniProtKB:Q9BTC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017922 ! GIPC1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:I0017337 ! znf408-rgs19ip1 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054392 name: O14913_HUMAN def: "Kruppel-associated box protein" [UniProtKB:O14913] xref: EMBL:AAB86475.1 xref: UniProtKB:O14913 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054393 name: TFEC_HUMAN def: "Transcription factor EC" [UniProtKB:O14948] synonym: "hTFEC-L" EXACT [UniProtKB:O14948] synonym: "Protein TFE-C" EXACT [UniProtKB:O14948] synonym: "Transcription factor EC-like" EXACT [UniProtKB:O14948] xref: EMBL:AAH29891.1 xref: EMBL:BAA21908.1 xref: EMBL:CAE77680.1 xref: EMBL:CAI45926.1 xref: EMBL:EAL24366.1 xref: EMBL:EAW83491.1 xref: EMBL:EAW83492.1 xref: UniProtKB:O14948 xref: UniProtKB:Q5H9U8 xref: UniProtKB:Q709A4 xref: UniProtKB:Q8N6J9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020249 ! TFEC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054394 name: RAB7L_HUMAN def: "Ras-related protein Rab-7L1" [UniProtKB:O14966] synonym: "Rab-7-like protein 1" EXACT [UniProtKB:O14966] xref: EMBL:AAH02585.1 xref: EMBL:BAA22160.1 xref: UniProtKB:O14966 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019607 ! RAB7L1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0017324 ! lsm7-rab7l1 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054395 name: HNRDL_HUMAN def: "Heterogeneous nuclear ribonucleoprotein D-like" [UniProtKB:O14979] synonym: "AU-rich element RNA-binding factor" EXACT [UniProtKB:O14979] synonym: "hnHNRP-DL" EXACT [UniProtKB:O14979] synonym: "hnRPD-like protein" EXACT [UniProtKB:O14979] synonym: "JKT41-binding protein" EXACT [UniProtKB:O14979] synonym: "Protein laAUF1" EXACT [UniProtKB:O14979] xref: EMBL:AAH07392.2 xref: EMBL:AAH11714.1 xref: EMBL:AAH71944.1 xref: EMBL:AAR17782.1 xref: EMBL:AAY40914.1 xref: EMBL:BAA22860.1 xref: EMBL:BAA24361.1 xref: EMBL:BAA75239.1 xref: EMBL:BAA75240.1 xref: EMBL:BAA75241.1 xref: EMBL:BAB62188.1 xref: EMBL:CAG28551.1 xref: UniProtKB:O14979 xref: UniProtKB:Q6SPF2 xref: UniProtKB:Q7KZ74 xref: UniProtKB:Q7KZ75 xref: UniProtKB:Q96IM0 xref: UniProtKB:Q96S43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018150 ! HNRPDL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001745 ! poly(A) binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066852 ! HNRDL_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0066853 ! HNRDL_HUMAN-Omega-N-methylated arginine408 [Term] id: CCO:B0054396 name: IPP4_HUMAN def: "Putative type-1 protein phosphatase inhibitor 4" [UniProtKB:O14990] synonym: "I-4" EXACT [UniProtKB:O14990] synonym: "Protein phosphatase 1, regulatory subunit 2 pseudogene 9" EXACT [UniProtKB:O14990] xref: EMBL:AAH56673.1 xref: EMBL:BAB18974.1 xref: EMBL:CAB08112.1 xref: UniProtKB:O14990 xref: UniProtKB:Q5H958 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018303 ! PPP1R2P9_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0054397 name: ARHGA_HUMAN def: "Rho guanine nucleotide exchange factor 10" [UniProtKB:O15013] xref: EMBL:AAB71662.1 xref: EMBL:AAH36809.1 xref: EMBL:AAH40474.1 xref: EMBL:BAA20754.2 xref: EMBL:CAH18365.1 xref: UniProtKB:O14665 xref: UniProtKB:O15013 xref: UniProtKB:Q68D55 xref: UniProtKB:Q8IWD9 xref: UniProtKB:Q8IY77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017019 ! ARHGEF10_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0054398 name: ZN646_HUMAN def: "Zinc finger protein 646" [UniProtKB:O15015] xref: EMBL:BAA20756.2 xref: UniProtKB:O15015 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006018 ! ZNF646_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054399 name: SPTN2_HUMAN def: "Spectrin beta chain, brain 2" [UniProtKB:O15020] synonym: "Beta-III spectrin" EXACT [UniProtKB:O15020] synonym: "Spectrin, non-erythroid beta chain 2" EXACT [UniProtKB:O15020] xref: EMBL:AAC79502.1 xref: EMBL:AAC79503.1 xref: EMBL:AAC79504.1 xref: EMBL:AAC80006.1 xref: EMBL:BAA32700.1 xref: UniProtKB:O14872 xref: UniProtKB:O14873 xref: UniProtKB:O15020 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020025 ! SPTBN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0070836 ! SPTN2_HUMAN-Phosphoserine2171 relationship: transforms_into CCO:B0070837 ! SPTN2_HUMAN-Phosphoserine2199 relationship: transforms_into CCO:B0070838 ! SPTN2_HUMAN-Phosphothreonine2354 [Term] id: CCO:B0054400 name: PER2_HUMAN def: "Period circadian protein homolog 2" [UniProtKB:O15055] synonym: "Circadian clock protein PERIOD 2" EXACT [UniProtKB:O15055] synonym: "hPER2" EXACT [UniProtKB:O15055] xref: EMBL:AAX88976.1 xref: EMBL:BAA20804.2 xref: EMBL:BAA83709.1 xref: UniProtKB:O15055 xref: UniProtKB:Q4ZG49 xref: UniProtKB:Q9UQ45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019367 ! PER2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016214 ! csnk1e-per2 phosphorylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069220 ! PER2_HUMAN-Phosphoserine527 relationship: transforms_into CCO:B0069221 ! PER2_HUMAN-Phosphoserine530 relationship: transforms_into CCO:B0069222 ! PER2_HUMAN-Phosphoserine533 relationship: transforms_into CCO:B0069223 ! PER2_HUMAN-Phosphoserine540 relationship: transforms_into CCO:B0069224 ! PER2_HUMAN-Phosphoserine662 relationship: transforms_into CCO:B0069225 ! PER2_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0069226 ! PER2_HUMAN-Phosphoserine700 relationship: transforms_into CCO:B0069227 ! PER2_HUMAN-Phosphoserine714 relationship: transforms_into CCO:B0069228 ! PER2_HUMAN-Phosphoserine766 relationship: transforms_into CCO:B0069229 ! PER2_HUMAN-Phosphoserine771 relationship: transforms_into CCO:B0069230 ! PER2_HUMAN-Phosphothreonine864 relationship: transforms_into CCO:B0069231 ! PER2_HUMAN-Phosphoserine945 relationship: transforms_into CCO:B0069232 ! PER2_HUMAN-Phosphoserine977 relationship: transforms_into CCO:B0069233 ! PER2_HUMAN-Phosphoserine1124 [Term] id: CCO:B0054401 name: ZBT39_HUMAN def: "Zinc finger and BTB domain-containing protein 39" [UniProtKB:O15060] xref: EMBL:BAA20809.2 xref: UniProtKB:O15060 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020556 ! ZBTB39_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054402 name: ZBTB5_HUMAN def: "Zinc finger and BTB domain-containing protein 5" [UniProtKB:O15062] xref: EMBL:AAH10007.1 xref: EMBL:BAA20811.2 xref: UniProtKB:O15062 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020569 ! ZBTB5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054403 name: MCF2L_HUMAN def: "Guanine nucleotide exchange factor DBS" [UniProtKB:O15068] synonym: "DBL's big sister" EXACT [UniProtKB:O15068] synonym: "MCF2-transforming sequence-like protein" EXACT [UniProtKB:O15068] xref: EMBL:AAH11853.1 xref: EMBL:AAH20208.1 xref: EMBL:BAA20817.1 xref: EMBL:BAC85569.1 xref: EMBL:BAD08351.1 xref: EMBL:BAD08352.1 xref: EMBL:CAH70243.1 xref: EMBL:CAH70244.2 xref: EMBL:CAH70245.1 xref: EMBL:CAI39523.1 xref: EMBL:CAI39524.2 xref: EMBL:CAI39525.1 xref: EMBL:CAI39869.1 xref: EMBL:CAI39870.2 xref: EMBL:CAI39871.1 xref: EMBL:CAI41383.1 xref: EMBL:CAI41390.2 xref: EMBL:CAI41392.1 xref: EMBL:CAI94923.1 xref: EMBL:CAI94928.1 xref: EMBL:CAI95103.1 xref: EMBL:CAI95400.1 xref: EMBL:CAM13074.1 xref: EMBL:CAM13075.1 xref: EMBL:CAM13089.1 xref: EMBL:CAM24069.2 xref: EMBL:CAM24070.1 xref: UniProtKB:A2A2X1 xref: UniProtKB:A2A2X2 xref: UniProtKB:A2A3G6 xref: UniProtKB:A2A3G8 xref: UniProtKB:O15068 xref: UniProtKB:Q5JU56 xref: UniProtKB:Q5VXT1 xref: UniProtKB:Q6ZWD4 xref: UniProtKB:Q765G8 xref: UniProtKB:Q765G9 xref: UniProtKB:Q8N679 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018585 ! MCF2L_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0068054 ! MCF2L_HUMAN-Phosphoserine975 [Term] id: CCO:B0054404 name: ARHGB_HUMAN def: "Rho guanine nucleotide exchange factor 11" [UniProtKB:O15085] synonym: "PDZ-RhoGEF" EXACT [UniProtKB:O15085] xref: EMBL:BAA20834.2 xref: EMBL:CAH70127.1 xref: EMBL:CAH72940.1 xref: UniProtKB:O15085 xref: UniProtKB:Q5VY40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017020 ! ARHGEF11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017293 ! kiaa1206-arhgef11 physical interaction relationship: participates_in CCO:I0018709 ! arhgef11-rhoa-1 direct interaction relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063545 ! ARHGB_HUMAN-Phosphoserine663 relationship: transforms_into CCO:B0063546 ! ARHGB_HUMAN-Phosphothreonine668 relationship: transforms_into CCO:B0063547 ! ARHGB_HUMAN-Phosphothreonine672 relationship: transforms_into CCO:B0063548 ! ARHGB_HUMAN-Phosphoserine1155 [Term] id: CCO:B0054405 name: ZN536_HUMAN def: "Zinc finger protein 536" [UniProtKB:O15090] xref: EMBL:BAA20844.2 xref: UniProtKB:O15090 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020803 ! ZNF536_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054406 name: SMAD7_HUMAN def: "Mothers against decapentaplegic homolog 7" [UniProtKB:O15105] synonym: "hSMAD7" EXACT [UniProtKB:O15105] synonym: "Mothers against DPP homolog 7" EXACT [UniProtKB:O15105] synonym: "SMAD 7" EXACT [UniProtKB:O15105] synonym: "Smad7" EXACT [UniProtKB:O15105] xref: EMBL:AAB81246.1 xref: EMBL:AAB81354.1 xref: EMBL:AAH74818.2 xref: EMBL:AAH74819.2 xref: EMBL:AAL68977.1 xref: UniProtKB:O14740 xref: UniProtKB:O15105 xref: UniProtKB:Q6DK23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019942 ! SMAD7_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004503 ! transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: transforms_into CCO:B0070607 ! SMAD7_HUMAN-N6-acetyllysine64 relationship: transforms_into CCO:B0070608 ! SMAD7_HUMAN-N6-acetyllysine70 relationship: transforms_into CCO:B0070609 ! SMAD7_HUMAN-Phosphoserine249 [Term] id: CCO:B0054407 name: FYB_HUMAN def: "FYN-binding protein" [UniProtKB:O15117] synonym: "ADAP" EXACT [UniProtKB:O15117] synonym: "Adhesion and degranulation promoting adaptor protein" EXACT [UniProtKB:O15117] synonym: "FYB-120/130" EXACT [UniProtKB:O15117] synonym: "FYN-T-binding protein" EXACT [UniProtKB:O15117] synonym: "p120/p130" EXACT [UniProtKB:O15117] synonym: "SLAP-130" EXACT [UniProtKB:O15117] synonym: "SLP-76-associated phosphoprotein" EXACT [UniProtKB:O15117] xref: EMBL:AAB62226.1 xref: EMBL:AAC51300.1 xref: UniProtKB:O00359 xref: UniProtKB:O15117 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017850 ! FYB_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0066319 ! FYB_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0066320 ! FYB_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0066321 ! FYB_HUMAN-Phosphothreonine158 relationship: transforms_into CCO:B0066322 ! FYB_HUMAN-Phosphotyrosine571 relationship: transforms_into CCO:B0066323 ! FYB_HUMAN-Phosphoserine573 [Term] id: CCO:B0054408 name: ANGP2_HUMAN def: "Angiopoietin-2 precursor" [UniProtKB:O15123] synonym: "ANG-2" EXACT [UniProtKB:O15123] xref: EMBL:AAB63190.1 xref: EMBL:AAF76526.1 xref: EMBL:AAI26201.1 xref: EMBL:AAI26203.1 xref: EMBL:BAA95590.1 xref: UniProtKB:A0AV38 xref: UniProtKB:O15123 xref: UniProtKB:Q9NRR7 xref: UniProtKB:Q9P2Y7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016973 ! ANGPT2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054409 name: NPFF_HUMAN def: "FMRFamide-related peptides precursor" [UniProtKB:O15130] xref: EMBL:AAB64288.1 xref: UniProtKB:O15130 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018834 ! NPFF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0068813 ! NPFF_HUMAN-Phenylalanine amide76 relationship: transforms_into CCO:B0068814 ! NPFF_HUMAN-Phenylalanine amide110 [Term] id: CCO:B0054410 name: MYT2_HUMAN def: "Replication initiation-like protein" [UniProtKB:O15150] synonym: "Cerebrin-50" EXACT [UniProtKB:O15150] synonym: "Myelin transcription factor 2" EXACT [UniProtKB:O15150] synonym: "MyT2" EXACT [UniProtKB:O15150] xref: EMBL:AAB34231.1 xref: EMBL:AAB62700.1 xref: UniProtKB:O15150 xref: UniProtKB:Q16301 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018705 ! MYT2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000419 ! DNA topoisomerase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054411 name: ZBT7B_HUMAN def: "Zinc finger and BTB domain-containing protein 7B" [UniProtKB:O15156] synonym: "hcKrox" EXACT [UniProtKB:O15156] synonym: "Krueppel-related zinc finger protein cKrox" EXACT [UniProtKB:O15156] synonym: "T-helper-inducing POZ/Krueppel-like factor" EXACT [UniProtKB:O15156] synonym: "Zfp-67" EXACT [UniProtKB:O15156] synonym: "Zinc finger and BTB domain-containing protein 15" EXACT [UniProtKB:O15156] synonym: "Zinc finger protein 67 homolog" EXACT [UniProtKB:O15156] synonym: "Zinc finger protein Th-POK" EXACT [UniProtKB:O15156] xref: EMBL:AAC51847.1 xref: EMBL:AAH12070.1 xref: EMBL:CAH18158.1 xref: EMBL:CAI13266.1 xref: UniProtKB:O15156 xref: UniProtKB:Q68DR2 xref: UniProtKB:Q96EP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020565 ! ZBTB7B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014968 ! grap2-zbtb7b physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054412 name: PSPHL_HUMAN def: "Putative phosphoserine phosphatase-like protein" [UniProtKB:O15172] synonym: "L-3-phosphoserine-phosphatase homolog" EXACT [UniProtKB:O15172] xref: EMBL:AAP35307.1 xref: EMBL:CAA04865.1 xref: UniProtKB:O15172 xref: UniProtKB:Q86U85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019533 ! PSPHL_human relationship: has_function CCO:F0001020 ! phosphoserine phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054413 name: BRAC_HUMAN def: "Brachyury protein" [UniProtKB:O15178] synonym: "T protein" EXACT [UniProtKB:O15178] xref: EMBL:CAA04938.1 xref: EMBL:CAI14269.1 xref: UniProtKB:O15178 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017177 ! T_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054414 name: SMAD9_HUMAN def: "Mothers against decapentaplegic homolog 9" [UniProtKB:O15198] synonym: "Madh6" EXACT [UniProtKB:O15198] synonym: "Mothers against DPP homolog 9" EXACT [UniProtKB:O15198] synonym: "SMAD 9" EXACT [UniProtKB:O15198] synonym: "Smad9" EXACT [UniProtKB:O15198] xref: EMBL:AAH11559.1 xref: EMBL:BAA21128.1 xref: EMBL:BAA21129.1 xref: UniProtKB:O14989 xref: UniProtKB:O15198 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019943 ! SMAD9_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015442 ! smad4-smad9 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: transforms_into CCO:B0070610 ! SMAD9_HUMAN-Phosphoserine465 relationship: transforms_into CCO:B0070611 ! SMAD9_HUMAN-Phosphoserine467 [Term] id: CCO:B0054415 name: ZBT22_HUMAN def: "Zinc finger and BTB domain-containing protein 22" [UniProtKB:O15209] synonym: "Protein BING1" EXACT [UniProtKB:O15209] synonym: "Zinc finger and BTB domain-containing protein 22A" EXACT [UniProtKB:O15209] synonym: "Zinc finger protein 297" EXACT [UniProtKB:O15209] xref: EMBL:AAH18541.1 xref: EMBL:BAG38101.1 xref: EMBL:CAB09990.1 xref: EMBL:CAI17526.1 xref: EMBL:CAI18123.1 xref: EMBL:CAI41787.2 xref: EMBL:CAQ08033.1 xref: UniProtKB:O15209 xref: UniProtKB:Q5HYV4 xref: UniProtKB:Q5STL0 xref: UniProtKB:Q5STR7 xref: UniProtKB:Q8WV82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020548 ! ZBTB22_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001238 ! retinoid-X receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004420 ! thyroid hormone receptor coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0005774 ! retinoic acid receptor binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015777 ! dnaja3-znf297 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054416 name: RGL2_HUMAN def: "Ral guanine nucleotide dissociation stimulator-like 2" [UniProtKB:O15211] synonym: "RalGDS-like factor" EXACT [UniProtKB:O15211] synonym: "RAS-associated protein RAB2L" EXACT [UniProtKB:O15211] xref: EMBL:AAH32681.1 xref: EMBL:BAA75926.1 xref: EMBL:CAB09992.1 xref: EMBL:CAB43361.1 xref: UniProtKB:O15211 xref: UniProtKB:Q9Y3F3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019694 ! RGL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0069910 ! RGL2_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0069911 ! RGL2_HUMAN-Phosphoserine617 [Term] id: CCO:B0054417 name: GP182_HUMAN def: "G-protein coupled receptor 182" [UniProtKB:O15218] xref: EMBL:AAH34761.1 xref: EMBL:AAP23201.1 xref: EMBL:CAA73910.1 xref: UniProtKB:O15218 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017990 ! GPR182_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054418 name: LAMA5_HUMAN def: "Laminin subunit alpha-5 precursor" [UniProtKB:O15230] xref: EMBL:BAA25459.1 xref: EMBL:BAB67800.1 xref: EMBL:CAB09137.1 xref: EMBL:CAC22310.1 xref: UniProtKB:O15230 xref: UniProtKB:Q8WZA7 xref: UniProtKB:Q9H1P1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018453 ! LAMA5_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:I0019277 ! muc7-lama5 physical interaction relationship: participates_in CCO:I0020564 ! btbd10-lama5 physical interaction relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0054419 name: CLIC2_HUMAN def: "Chloride intracellular channel protein 2" [UniProtKB:O15247] synonym: "XAP121" EXACT [UniProtKB:O15247] xref: EMBL:AAH22305.1 xref: EMBL:CAA03948.1 xref: EMBL:CAA73228.1 xref: EMBL:CAI41464.1 xref: UniProtKB:O15174 xref: UniProtKB:O15247 xref: UniProtKB:Q5JT80 xref: UniProtKB:Q8TCE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017385 ! CLIC2_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001515 ! voltage-gated chloride channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054420 name: NPHP1_HUMAN def: "Nephrocystin-1" [UniProtKB:O15259] synonym: "Juvenile nephronophthisis 1 protein" EXACT [UniProtKB:O15259] xref: EMBL:AAC51771.1 xref: EMBL:AAH09789.1 xref: EMBL:AAH62574.1 xref: EMBL:CAA05030.1 xref: UniProtKB:O14837 xref: UniProtKB:O15259 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018835 ! NPHP1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0017536 ! nphp1-ubqln4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054421 name: DEFB2_HUMAN def: "Beta-defensin 2 precursor" [UniProtKB:O15263] synonym: "BD-2" EXACT [UniProtKB:O15263] synonym: "Defensin, beta 2" EXACT [UniProtKB:O15263] synonym: "hBD-2" EXACT [UniProtKB:O15263] synonym: "SAP1" EXACT [UniProtKB:O15263] synonym: "Skin-antimicrobial peptide 1" EXACT [UniProtKB:O15263] xref: EMBL:AAC33549.1 xref: EMBL:AAC69554.1 xref: EMBL:AAH69285.1 xref: EMBL:AAH93983.1 xref: EMBL:AAH93985.1 xref: EMBL:CAA95992.1 xref: EMBL:CAB65126.1 xref: UniProtKB:O15263 xref: UniProtKB:Q52LC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022182 ! DEFB4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054422 name: SHOX_HUMAN def: "Short stature homeobox protein" [UniProtKB:O15266] synonym: "Pseudoautosomal homeobox-containing osteogenic protein" EXACT [UniProtKB:O15266] synonym: "Short stature homeobox-containing protein" EXACT [UniProtKB:O15266] xref: EMBL:AAC18820.1 xref: EMBL:CAA72298.1 xref: EMBL:CAA72299.1 xref: UniProtKB:O00412 xref: UniProtKB:O00413 xref: UniProtKB:O15266 xref: UniProtKB:O15267 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019900 ! SHOX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054423 name: SIVA_HUMAN def: "Apoptosis regulatory protein Siva" [UniProtKB:O15304] synonym: "CD27-binding protein" EXACT [UniProtKB:O15304] synonym: "CD27BP" EXACT [UniProtKB:O15304] xref: EMBL:AAC51372.1 xref: EMBL:AAD50057.1 xref: EMBL:AAH34562.1 xref: EMBL:AAL02171.1 xref: EMBL:DAA01049.1 xref: UniProtKB:O15304 xref: UniProtKB:Q96P98 xref: UniProtKB:Q9UPD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019919 ! SIVA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018025 ! cd27-siva physical interaction relationship: participates_in CCO:I0018026 ! cd27-siva-1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0070563 ! SIVA_HUMAN-Phosphotyrosine34 [Term] id: CCO:B0054424 name: O15309_HUMAN xref: UniProtKB:O15309 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054425 name: O15310_HUMAN def: "Polymerase" [UniProtKB:O15310] xref: EMBL:AAB63113.1 xref: UniProtKB:O15310 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054426 name: O15311_HUMAN def: "Polymerase" [UniProtKB:O15311] xref: EMBL:AAB63114.1 xref: UniProtKB:O15311 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054427 name: O15313_HUMAN def: "Polymerase" [UniProtKB:O15313] xref: EMBL:AAB63116.1 xref: UniProtKB:O15313 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054428 name: RPC7_HUMAN def: "DNA-directed RNA polymerase III subunit RPC7" [UniProtKB:O15318] synonym: "DNA-directed RNA polymerase III 32 kDa polypeptide" EXACT [UniProtKB:O15318] synonym: "DNA-directed RNA polymerase III subunit G" EXACT [UniProtKB:O15318] synonym: "RNA polymerase III subunit C7" EXACT [UniProtKB:O15318] synonym: "RPC32" EXACT [UniProtKB:O15318] xref: EMBL:AAB63676.1 xref: UniProtKB:O15318 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019783 ! POLR3G_human relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000271 ! DNA-directed RNA polymerase III complex relationship: participates_in CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter relationship: transforms_into CCO:B0070160 ! RPC7_HUMAN-Phosphoserine157 [Term] id: CCO:B0054429 name: INP4B_HUMAN def: "Type II inositol-3,4-bisphosphate 4-phosphatase" [UniProtKB:O15327] synonym: "EC 3.1.3.66" EXACT [UniProtKB:O15327] synonym: "Inositol polyphosphate 4-phosphatase type II" EXACT [UniProtKB:O15327] xref: EMBL:AAB72153.1 xref: EMBL:AAH17924.1 xref: EMBL:AAH72447.1 xref: UniProtKB:O15327 xref: UniProtKB:Q6IN59 xref: UniProtKB:Q6PJB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018289 ! INPP4B_human relationship: has_function CCO:F0003121 ! phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054430 name: CHAD_HUMAN def: "Chondroadherin precursor" [UniProtKB:O15335] synonym: "Cartilage leucine-rich protein" EXACT [UniProtKB:O15335] xref: EMBL:AAC13410.1 xref: EMBL:AAH36360.1 xref: EMBL:AAH73974.1 xref: EMBL:AAK51556.1 xref: UniProtKB:O15335 xref: UniProtKB:Q6GTU0 xref: UniProtKB:Q96RJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017348 ! CHAD_human relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0054431 name: FOXN1_HUMAN def: "Forkhead box protein N1" [UniProtKB:O15353] synonym: "Winged-helix transcription factor nude" EXACT [UniProtKB:O15353] xref: EMBL:CAA72416.1 xref: EMBL:CAA72417.1 xref: UniProtKB:O15352 xref: UniProtKB:O15353 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017824 ! FOXN1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002917 ! epithelial cell proliferation [Term] id: CCO:B0054432 name: GPR37_HUMAN def: "Probable G-protein coupled receptor 37 precursor" [UniProtKB:O15354] synonym: "Endothelin B receptor-like protein 1" EXACT [UniProtKB:O15354] synonym: "ETBR-LP-1" EXACT [UniProtKB:O15354] synonym: "PAELR" EXACT [UniProtKB:O15354] synonym: "Parkin-associated endothelin receptor-like receptor" EXACT [UniProtKB:O15354] xref: EMBL:AAB70008.1 xref: EMBL:AAC51281.1 xref: EMBL:AAD08853.1 xref: EMBL:AAH40007.1 xref: EMBL:AAM18625.2 xref: EMBL:CAA73080.1 xref: UniProtKB:O00348 xref: UniProtKB:O14768 xref: UniProtKB:O15354 xref: UniProtKB:Q8TD39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018018 ! GPR37_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054433 name: EIF3H_HUMAN def: "Eukaryotic translation initiation factor 3 subunit H" [UniProtKB:O15372] synonym: "eIF-3 gamma" EXACT [UniProtKB:O15372] synonym: "eIF3 p40 subunit" EXACT [UniProtKB:O15372] synonym: "eIF3h" EXACT [UniProtKB:O15372] synonym: "Eukaryotic translation initiation factor 3 subunit 3" EXACT [UniProtKB:O15372] xref: EMBL:AAC84044.1 xref: EMBL:AAD03465.1 xref: EMBL:AAH00386.1 xref: UniProtKB:O15372 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017679 ! EIF3H_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0015377 ! abi3-eif3s3 physical interaction relationship: participates_in CCO:I0017429 ! disc1-eif3s3-6 physical interaction relationship: participates_in CCO:I0017430 ! disc1-eif3s3-7 physical interaction relationship: participates_in CCO:I0017817 ! disc1-eif3s3-5 physical interaction relationship: participates_in CCO:I0018086 ! disc1-eif3s3 physical interaction relationship: participates_in CCO:I0018088 ! disc1-eif3s3-4 physical interaction relationship: participates_in CCO:I0018367 ! disc1-eif3s3-2 physical interaction relationship: participates_in CCO:I0018543 ! disc1-eif3s3-1 physical interaction relationship: participates_in CCO:I0018642 ! disc1-eif3s3-3 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0064967 ! EIF3H_HUMAN-Phosphothreonine8 relationship: transforms_into CCO:B0064968 ! EIF3H_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0064969 ! EIF3H_HUMAN-Phosphothreonine11 relationship: transforms_into CCO:B0064970 ! EIF3H_HUMAN-Phosphoserine183 [Term] id: CCO:B0054434 name: O15376_HUMAN def: "CDC42 GAP-related protein" [UniProtKB:O15376] xref: EMBL:AAB66594.1 xref: UniProtKB:O15376 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054435 name: TOX3_HUMAN def: "TOX high mobility group box family member 3" [UniProtKB:O15405] synonym: "CAG trinucleotide repeat-containing gene F9 protein" EXACT [UniProtKB:O15405] synonym: "Trinucleotide repeat-containing gene 9 protein" EXACT [UniProtKB:O15405] xref: EMBL:AAB91435.1 xref: UniProtKB:O15405 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020326 ! TOX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054436 name: CCL25_HUMAN def: "C-C motif chemokine 25 precursor" [UniProtKB:O15444] synonym: "Chemokine TECK" EXACT [UniProtKB:O15444] synonym: "Small-inducible cytokine A25" EXACT [UniProtKB:O15444] synonym: "Thymus-expressed chemokine" EXACT [UniProtKB:O15444] xref: EMBL:AAB69981.1 xref: EMBL:AAI30562.1 xref: EMBL:BAB62257.1 xref: EMBL:EAW68952.1 xref: UniProtKB:A1L4J4 xref: UniProtKB:O15444 xref: UniProtKB:Q96KJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017270 ! CCL25_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054437 name: RPA34_HUMAN def: "DNA-directed RNA polymerase I subunit RPA34" [UniProtKB:O15446] synonym: "A34.5" EXACT [UniProtKB:O15446] synonym: "Anti-sense to ERCC-1 protein" EXACT [UniProtKB:O15446] synonym: "ASE-1" EXACT [UniProtKB:O15446] synonym: "CAST" EXACT [UniProtKB:O15446] synonym: "CD3-epsilon-associated protein" EXACT [UniProtKB:O15446] synonym: "CD3E-associated protein" EXACT [UniProtKB:O15446] synonym: "RNA polymerase I-associated factor PAF49" EXACT [UniProtKB:O15446] xref: EMBL:AAB68608.1 xref: EMBL:AAD41158.1 xref: EMBL:AAH38992.1 xref: EMBL:AAH54044.1 xref: EMBL:AAI08890.1 xref: UniProtKB:O15446 xref: UniProtKB:Q32N11 xref: UniProtKB:Q7Z5U2 xref: UniProtKB:Q9UPF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019776 ! CD3EAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017165 ! nfkbib-ase_1 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0070146 ! RPA34_HUMAN-Phosphotyrosine80 relationship: transforms_into CCO:B0070147 ! RPA34_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0070148 ! RPA34_HUMAN-Phosphoserine309 [Term] id: CCO:B0054438 name: TLR3_HUMAN def: "Toll-like receptor 3 precursor" [UniProtKB:O15455] synonym: "CD283 antigen" EXACT [UniProtKB:O15455] xref: EMBL:AAC34134.1 xref: UniProtKB:O15455 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020279 ! TLR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002272 ! positive regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002297 ! positive regulation of interferon-alpha biosynthetic process relationship: participates_in CCO:P0002300 ! positive regulation of interferon-beta biosynthetic process relationship: participates_in CCO:P0002485 ! negative regulation of osteoclast differentiation relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0071418 ! TLR3_HUMAN-Phosphotyrosine759 relationship: transforms_into CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 [Term] id: CCO:B0054439 name: GSC2_HUMAN def: "Homeobox protein goosecoid-2" [UniProtKB:O15499] synonym: "GSC-2" EXACT [UniProtKB:O15499] synonym: "Homeobox protein goosecoid-like" EXACT [UniProtKB:O15499] xref: EMBL:AAC39544.1 xref: UniProtKB:O15499 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018082 ! GSC2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054440 name: INSI1_HUMAN def: "Insulin-induced gene 1 protein" [UniProtKB:O15503] synonym: "INSIG-1" EXACT [UniProtKB:O15503] xref: EMBL:AAB69121.1 xref: EMBL:AAH01880.1 xref: EMBL:AAM44086.1 xref: EMBL:AAP35891.1 xref: EMBL:EAL23729.1 xref: UniProtKB:O15503 xref: UniProtKB:Q53XW8 xref: UniProtKB:Q9BUV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018290 ! INSIG1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054441 name: ARPC5_HUMAN def: "Actin-related protein 2/3 complex subunit 5" [UniProtKB:O15511] synonym: "Arp2/3 complex 16 kDa subunit" EXACT [UniProtKB:O15511] synonym: "p16-ARC" EXACT [UniProtKB:O15511] xref: EMBL:AAB64193.1 xref: EMBL:AAB70561.1 xref: EMBL:AAH57237.1 xref: EMBL:CAC19687.1 xref: EMBL:CAI19482.1 xref: EMBL:EAW91163.1 xref: UniProtKB:A6NEC4 xref: UniProtKB:O15511 xref: UniProtKB:Q6PG42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017048 ! ARPC5_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000443 ! Arp2/3 protein complex relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0054442 name: CFLAR_HUMAN def: "CASP8 and FADD-like apoptosis regulator precursor" [UniProtKB:O15519] synonym: "c-FLIP" EXACT [UniProtKB:O15519] synonym: "CASH" EXACT [UniProtKB:O15519] synonym: "Caspase homolog" EXACT [UniProtKB:O15519] synonym: "Caspase-eight-related protein" EXACT [UniProtKB:O15519] synonym: "Caspase-like apoptosis regulatory protein" EXACT [UniProtKB:O15519] synonym: "Casper" EXACT [UniProtKB:O15519] synonym: "Cellular FLICE-like inhibitory protein" EXACT [UniProtKB:O15519] synonym: "CLARP" EXACT [UniProtKB:O15519] synonym: "FADD-like antiapoptotic molecule 1" EXACT [UniProtKB:O15519] synonym: "FLAME-1" EXACT [UniProtKB:O15519] synonym: "I-FLICE" EXACT [UniProtKB:O15519] synonym: "Inhibitor of FLICE" EXACT [UniProtKB:O15519] synonym: "MACH-related inducer of toxicity" EXACT [UniProtKB:O15519] synonym: "MRIT" EXACT [UniProtKB:O15519] synonym: "Usurpin" EXACT [UniProtKB:O15519] xref: EMBL:AAB64110.1 xref: EMBL:AAB70909.1 xref: EMBL:AAB70910.1 xref: EMBL:AAB70911.1 xref: EMBL:AAB70912.1 xref: EMBL:AAB82648.1 xref: EMBL:AAB99790.1 xref: EMBL:AAB99791.1 xref: EMBL:AAB99792.1 xref: EMBL:AAB99793.1 xref: EMBL:AAB99794.1 xref: EMBL:AAC15825.1 xref: EMBL:AAC15826.1 xref: EMBL:AAC16439.1 xref: EMBL:AAC16440.1 xref: EMBL:AAC16441.1 xref: EMBL:AAC51622.1 xref: EMBL:AAC51623.1 xref: EMBL:AAH01602.1 xref: EMBL:AAP35397.1 xref: EMBL:BAB32552.1 xref: EMBL:CAA74366.1 xref: EMBL:CAA74367.1 xref: UniProtKB:O14673 xref: UniProtKB:O14674 xref: UniProtKB:O14675 xref: UniProtKB:O15137 xref: UniProtKB:O15138 xref: UniProtKB:O15356 xref: UniProtKB:O15510 xref: UniProtKB:O15519 xref: UniProtKB:O43618 xref: UniProtKB:O43619 xref: UniProtKB:O43620 xref: UniProtKB:O60458 xref: UniProtKB:O60459 xref: UniProtKB:Q96TE4 xref: UniProtKB:Q9UEW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017340 ! CFLAR_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0016253 ! tradd-traf2-2 physical interaction relationship: participates_in CCO:I0016254 ! tnfsf6-tnfrsf6-2 physical interaction relationship: participates_in CCO:I0018012 ! casp8-casp10-1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054443 name: SOCS1_HUMAN def: "Suppressor of cytokine signaling 1" [UniProtKB:O15524] synonym: "JAB" EXACT [UniProtKB:O15524] synonym: "JAK-binding protein" EXACT [UniProtKB:O15524] synonym: "SOCS-1" EXACT [UniProtKB:O15524] synonym: "SSI-1" EXACT [UniProtKB:O15524] synonym: "STAT-induced STAT inhibitor 1" EXACT [UniProtKB:O15524] synonym: "Tec-interacting protein 3" EXACT [UniProtKB:O15524] synonym: "TIP-3" EXACT [UniProtKB:O15524] xref: EMBL:AAB62401.1 xref: EMBL:AAD27709.1 xref: EMBL:BAA21537.1 xref: EMBL:BAA22431.1 xref: EMBL:BAA23521.1 xref: EMBL:CAB92528.1 xref: UniProtKB:O15097 xref: UniProtKB:O15524 xref: UniProtKB:Q9NSA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019972 ! SOCS1_human relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004133 ! kinase inhibitor activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002083 ! negative regulation of tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002693 ! negative regulation of JAK-STAT cascade relationship: participates_in CCO:P0002705 ! negative regulation of insulin receptor signaling pathway [Term] id: CCO:B0054444 name: GPR42_HUMAN def: "Putative G-protein coupled receptor 42" [UniProtKB:O15529] xref: EMBL:AAB67885.1 xref: EMBL:AAB86712.1 xref: UniProtKB:O15529 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018021 ! GPR42P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054445 name: PER1_HUMAN def: "Period circadian protein homolog 1" [UniProtKB:O15534] synonym: "Circadian clock protein PERIOD 1" EXACT [UniProtKB:O15534] synonym: "Circadian pacemaker protein Rigui" EXACT [UniProtKB:O15534] synonym: "hPER1" EXACT [UniProtKB:O15534] xref: EMBL:AAC51765.1 xref: EMBL:AAF15544.1 xref: EMBL:BAA22633.1 xref: EMBL:BAA94085.1 xref: EMBL:BAC06326.2 xref: UniProtKB:O15534 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019366 ! PER1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0069213 ! PER1_HUMAN-Phosphoserine979 relationship: transforms_into CCO:B0069214 ! PER1_HUMAN-Phosphoserine980 relationship: transforms_into CCO:B0069215 ! PER1_HUMAN-Phosphoserine1100 relationship: transforms_into CCO:B0069216 ! PER1_HUMAN-Phosphoserine1103 relationship: transforms_into CCO:B0069217 ! PER1_HUMAN-Phosphoserine1104 relationship: transforms_into CCO:B0069218 ! PER1_HUMAN-Phosphoserine1262 relationship: transforms_into CCO:B0069219 ! PER1_HUMAN-Phosphoserine1263 [Term] id: CCO:B0054446 name: ZN193_HUMAN def: "Zinc finger protein 193" [UniProtKB:O15535] synonym: "PRD51" EXACT [UniProtKB:O15535] synonym: "Zinc finger and SCAN domain-containing protein 9" EXACT [UniProtKB:O15535] xref: EMBL:AAC51659.1 xref: EMBL:AAC51661.1 xref: EMBL:AAH10374.1 xref: EMBL:CAA18533.1 xref: UniProtKB:O15535 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020648 ! ZNF193_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015735 ! znf193-znf446 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054447 name: P2RX6_HUMAN def: "P2X purinoceptor 6" [UniProtKB:O15547] synonym: "ATP receptor" EXACT [UniProtKB:O15547] synonym: "P2X6" EXACT [UniProtKB:O15547] synonym: "P2XM" EXACT [UniProtKB:O15547] synonym: "Purinergic receptor" EXACT [UniProtKB:O15547] synonym: "Purinergic receptor P2X-like 1" EXACT [UniProtKB:O15547] xref: EMBL:AAF13303.1 xref: EMBL:AAH33488.1 xref: EMBL:BAA22046.1 xref: EMBL:BAA22047.1 xref: EMBL:CAG30421.1 xref: UniProtKB:O15547 xref: UniProtKB:Q58F04 xref: UniProtKB:Q6IC33 xref: UniProtKB:Q9UL50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019263 ! P2RX6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069015 ! P2RX6_HUMAN-Phosphotyrosine54 [Term] id: CCO:B0054448 name: FFAR2_HUMAN def: "Free fatty acid receptor 2" [UniProtKB:O15552] synonym: "G-protein coupled receptor 43" EXACT [UniProtKB:O15552] xref: EMBL:AAB67886.1 xref: EMBL:AAB86713.1 xref: EMBL:AAH95535.1 xref: EMBL:AAH96198.1 xref: EMBL:AAH96199.1 xref: EMBL:AAH96200.1 xref: EMBL:AAH96201.1 xref: UniProtKB:O15552 xref: UniProtKB:Q4VAZ3 xref: UniProtKB:Q4VAZ5 xref: UniProtKB:Q4VBL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017782 ! FFAR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054449 name: SGSM2_HUMAN def: "Small G protein signaling modulator 2" [UniProtKB:O43147] synonym: "RUN and TBC1 domain-containing protein 1" EXACT [UniProtKB:O43147] xref: EMBL:AAH39204.1 xref: EMBL:AAH40590.1 xref: EMBL:BAA23693.3 xref: EMBL:BAC86084.1 xref: EMBL:BAF63512.1 xref: UniProtKB:A5LGW2 xref: UniProtKB:O43147 xref: UniProtKB:Q49AC2 xref: UniProtKB:Q6ZUY2 xref: UniProtKB:Q8IXU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019883 ! SGSM2_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054450 name: DDEF2_HUMAN def: "Development and differentiation-enhancing factor 2" [UniProtKB:O43150] synonym: "PAG3" EXACT [UniProtKB:O43150] synonym: "PAP" EXACT [UniProtKB:O43150] synonym: "Paxillin-associated protein with ARFGAP activity 3" EXACT [UniProtKB:O43150] synonym: "Pyk2 C-terminus-associated protein" EXACT [UniProtKB:O43150] xref: EMBL:AAH63308.1 xref: EMBL:BAA23696.2 xref: UniProtKB:O43150 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017540 ! DDEF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017290 ! kiaa0960-ddef2 physical interaction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0064689 ! DDEF2_HUMAN-Phosphoserine701 [Term] id: CCO:B0054451 name: PLXB1_HUMAN def: "Plexin-B1 precursor" [UniProtKB:O43157] synonym: "Semaphorin receptor SEP" EXACT [UniProtKB:O43157] xref: EMBL:BAA23703.2 xref: EMBL:CAB56221.1 xref: EMBL:CAB56222.1 xref: EMBL:CAB57277.1 xref: UniProtKB:O43157 xref: UniProtKB:Q6NY20 xref: UniProtKB:Q9UIV7 xref: UniProtKB:Q9UJ92 xref: UniProtKB:Q9UJ93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019450 ! PLXNB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003598 ! semaphorin receptor activity relationship: has_function CCO:F0004348 ! semaphorin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017823 ! plxnb1-rnd1-1 physical interaction relationship: participates_in CCO:I0017824 ! plxnb1-rnd3-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002950 ! positive regulation of axonogenesis [Term] id: CCO:B0054452 name: SI1L1_HUMAN def: "Signal-induced proliferation-associated 1-like protein 1" [UniProtKB:O43166] synonym: "E6-targeted protein 1" EXACT [UniProtKB:O43166] synonym: "High-risk human papilloma viruses E6 oncoproteins targeted protein 1" EXACT [UniProtKB:O43166] synonym: "SIPA1-like protein 1" EXACT [UniProtKB:O43166] xref: EMBL:AAC83179.1 xref: EMBL:AAD12543.1 xref: EMBL:AAD12544.1 xref: EMBL:BAA23712.2 xref: UniProtKB:O43166 xref: UniProtKB:O95321 xref: UniProtKB:Q9UDU4 xref: UniProtKB:Q9UNU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019903 ! SIPA1L1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0017286 ! kiaa0578-kiaa0440 physical interaction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0070520 ! SI1L1_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0070521 ! SI1L1_HUMAN-Phosphoserine1257 relationship: transforms_into CCO:B0070522 ! SI1L1_HUMAN-Phosphoserine1270 relationship: transforms_into CCO:B0070523 ! SI1L1_HUMAN-Phosphoserine1433 relationship: transforms_into CCO:B0070524 ! SI1L1_HUMAN-Phosphoserine1528 relationship: transforms_into CCO:B0070525 ! SI1L1_HUMAN-Phosphoserine1549 relationship: transforms_into CCO:B0070526 ! SI1L1_HUMAN-Phosphoserine1568 relationship: transforms_into CCO:B0070527 ! SI1L1_HUMAN-Phosphoserine1585 [Term] id: CCO:B0054453 name: ZBT24_HUMAN def: "Zinc finger and BTB domain-containing protein 24" [UniProtKB:O43167] synonym: "Zinc finger protein 450" EXACT [UniProtKB:O43167] xref: EMBL:AAH36731.1 xref: EMBL:AAI17375.1 xref: EMBL:AAI17377.1 xref: EMBL:BAA23713.2 xref: EMBL:CAI23346.1 xref: UniProtKB:O43167 xref: UniProtKB:Q17RC6 xref: UniProtKB:Q5TED5 xref: UniProtKB:Q8N455 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020549 ! ZBTB24_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054454 name: NDUS4_HUMAN def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial precursor" [UniProtKB:O43181] synonym: "CI-18 kDa" EXACT [UniProtKB:O43181] synonym: "CI-AQDQ" EXACT [UniProtKB:O43181] synonym: "Complex I-18 kDa" EXACT [UniProtKB:O43181] synonym: "Complex I-AQDQ" EXACT [UniProtKB:O43181] synonym: "NADH-ubiquinone oxidoreductase 18 kDa subunit" EXACT [UniProtKB:O43181] xref: EMBL:AAB87865.1 xref: EMBL:AAH05270.1 xref: UniProtKB:O43181 xref: UniProtKB:Q9BS69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018745 ! NDUFS4_human relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_function CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0001149 ! cAMP-mediated signaling relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: transforms_into CCO:B0068552 ! NDUS4_HUMAN-Phosphothreonine32 relationship: transforms_into CCO:B0068553 ! NDUS4_HUMAN-Phosphoserine34 [Term] id: CCO:B0054455 name: RHG06_HUMAN def: "Rho GTPase-activating protein 6" [UniProtKB:O43182] synonym: "Rho-type GTPase-activating protein 6" EXACT [UniProtKB:O43182] synonym: "Rho-type GTPase-activating protein RhoGAPX-1" EXACT [UniProtKB:O43182] xref: EMBL:AAC98539.2 xref: EMBL:AAC98540.2 xref: EMBL:AAD53166.1 xref: EMBL:AAD55087.1 xref: EMBL:AAF43261.1 xref: UniProtKB:O43182 xref: UniProtKB:O43437 xref: UniProtKB:Q9P1B3 xref: UniProtKB:Q9UK81 xref: UniProtKB:Q9UK82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019716 ! ARHGAP6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0069941 ! RHG06_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0069942 ! RHG06_HUMAN-Phosphoserine663 relationship: transforms_into CCO:B0069943 ! RHG06_HUMAN-Phosphoserine673 relationship: transforms_into CCO:B0069944 ! RHG06_HUMAN-Phosphoserine754 relationship: transforms_into CCO:B0069945 ! RHG06_HUMAN-Phosphoserine777 relationship: transforms_into CCO:B0069946 ! RHG06_HUMAN-Phosphoserine928 relationship: transforms_into CCO:B0069947 ! RHG06_HUMAN-Phosphoserine939 [Term] id: CCO:B0054456 name: CRX_HUMAN def: "Cone-rod homeobox protein" [UniProtKB:O43186] xref: EMBL:AAB88418.1 xref: EMBL:AAH16664.1 xref: EMBL:AAH53672.1 xref: EMBL:AAP36028.1 xref: UniProtKB:O43186 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017465 ! CRX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0015390 ! crx-loc130951 physical interaction relationship: participates_in CCO:I0015770 ! crx-mdfi physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002697 ! positive regulation of photoreceptor cell differentiation [Term] id: CCO:B0054457 name: IRAK2_HUMAN def: "Interleukin-1 receptor-associated kinase-like 2" [UniProtKB:O43187] synonym: "IRAK-2" EXACT [UniProtKB:O43187] xref: EMBL:AAB87669.1 xref: EMBL:AAI25185.1 xref: EMBL:CAD43180.3 xref: UniProtKB:O43187 xref: UniProtKB:Q08AG6 xref: UniProtKB:Q5K546 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018309 ! IRAK2_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001070 ! NF-kappaB-inducing kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0016268 ! tirap-irak2 physical interaction relationship: participates_in CCO:I0017991 ! irak2-myd88-ex1 physical interaction relationship: participates_in CCO:I0017994 ! irak2-traf6-ex1 physical interaction relationship: participates_in CCO:I0017996 ! irak2-irak2-ex1 physical interaction relationship: participates_in CCO:I0017998 ! irak1-irak2-ex1 physical interaction relationship: participates_in CCO:I0018000 ! irak2-irak1-ex1 physical interaction relationship: participates_in CCO:I0018001 ! irak2-irak3-ex1 physical interaction relationship: participates_in CCO:I0018003 ! irak3-irak2-ex1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054458 name: O43192_HUMAN def: "Vasopressin receptor type 2" [UniProtKB:O43192] synonym: "Arginine vasopressin receptor 2 (Nephrogenic diabetes insipidus), isoform CRA_b" EXACT [UniProtKB:O43192] xref: EMBL:AAB87678.1 xref: EMBL:EAW72784.1 xref: UniProtKB:O43192 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020430 ! AVPR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001338 ! vasopressin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054459 name: MTLR_HUMAN def: "Motilin receptor" [UniProtKB:O43193] synonym: "G-protein coupled receptor 38" EXACT [UniProtKB:O43193] xref: EMBL:AAC26081.1 xref: EMBL:AAT35806.1 xref: EMBL:CAC19107.1 xref: UniProtKB:O43193 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018680 ! MLNR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003195 ! growth hormone-releasing hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054460 name: GPR39_HUMAN def: "Probable G-protein coupled receptor 39" [UniProtKB:O43194] xref: EMBL:AAC26082.1 xref: EMBL:AAI25047.1 xref: EMBL:AAY24154.1 xref: UniProtKB:O43194 xref: UniProtKB:Q08AS2 xref: UniProtKB:Q53R01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018019 ! GPR39_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066545 ! GPR39_HUMAN-Phosphoserine380 [Term] id: CCO:B0054461 name: O43245_HUMAN def: "Protein p65" [UniProtKB:O43245] xref: EMBL:CAA05410.2 xref: UniProtKB:O43245 xref: UniProtKB:Q99899 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021064 ! p65_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054462 name: HXC11_HUMAN def: "Homeobox protein Hox-C11" [UniProtKB:O43248] xref: EMBL:AAH01543.1 xref: EMBL:CAA03876.1 xref: UniProtKB:O43248 xref: UniProtKB:Q96DH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018185 ! HOXC11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054463 name: RBM9_HUMAN def: "RNA-binding protein 9" [UniProtKB:O43251] synonym: "Fox-1 homolog B" EXACT [UniProtKB:O43251] synonym: "Hexaribonucleotide-binding protein 2" EXACT [UniProtKB:O43251] synonym: "Repressor of tamoxifen transcriptional activity" EXACT [UniProtKB:O43251] synonym: "RNA-binding motif protein 9" EXACT [UniProtKB:O43251] xref: EMBL:AAH13115.1 xref: EMBL:AAH25281.1 xref: EMBL:AAL67150.1 xref: EMBL:AAL71905.1 xref: EMBL:AAX84843.1 xref: EMBL:ABG77459.1 xref: EMBL:BAB70875.1 xref: EMBL:BAF84149.1 xref: EMBL:CAA15842.1 xref: EMBL:CAG30445.1 xref: EMBL:CAI19059.1 xref: EMBL:CAI20525.1 xref: EMBL:CAL91352.1 xref: UniProtKB:A4F5G8 xref: UniProtKB:A8K5Z5 xref: UniProtKB:O43251 xref: UniProtKB:Q0PRL5 xref: UniProtKB:Q0VH35 xref: UniProtKB:Q5TF71 xref: UniProtKB:Q6IC09 xref: UniProtKB:Q8TD00 xref: UniProtKB:Q8WYB1 xref: UniProtKB:Q96DZ6 xref: UniProtKB:Q96NL7 xref: UniProtKB:Q9UGW4 xref: UniProtKB:Q9UH33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019648 ! RBM9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015225 ! pepp2-rbm9 physical interaction relationship: participates_in CCO:I0015420 ! dazap2-rbm9 physical interaction relationship: participates_in CCO:I0015641 ! rbm9-rbpms physical interaction relationship: participates_in CCO:I0016170 ! atxn1-rbm9 physical interaction relationship: participates_in CCO:I0016178 ! a2bp1-rbm9 physical interaction relationship: participates_in CCO:I0017606 ! atxn1-rbm9-5 physical interaction relationship: participates_in CCO:I0018908 ! a2bp1-rbm9-1 physical interaction relationship: participates_in CCO:I0018939 ! atn1-rbm9 physical interaction relationship: participates_in CCO:I0018957 ! atxn1-rbm9-1 physical interaction relationship: participates_in CCO:I0018979 ! atxn1-rbm9-2 physical interaction relationship: participates_in CCO:I0019006 ! atxn1-rbm9-3 physical interaction relationship: participates_in CCO:I0019057 ! atxn1-rbm9-4 physical interaction relationship: participates_in CCO:I0019168 ! rere-rbm9 physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0054464 name: O43266_HUMAN def: "Extracellular matrix protein 1" [UniProtKB:O43266] xref: EMBL:AAB88082.1 xref: UniProtKB:O43266 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054465 name: PROD_HUMAN def: "Proline oxidase, mitochondrial precursor" [UniProtKB:O43272] synonym: "EC 1.5.99.8" EXACT [UniProtKB:O43272] synonym: "p53-induced gene 6 protein" EXACT [UniProtKB:O43272] synonym: "Proline dehydrogenase" EXACT [UniProtKB:O43272] synonym: "Proline oxidase 2" EXACT [UniProtKB:O43272] xref: EMBL:AAB88789.1 xref: EMBL:AAC39529.1 xref: EMBL:AAD24775.1 xref: EMBL:AAF21464.1 xref: EMBL:AAH68260.1 xref: EMBL:AAH94736.1 xref: EMBL:AAI18598.1 xref: EMBL:AAI21810.1 xref: EMBL:BAD92709.1 xref: UniProtKB:A6NF53 xref: UniProtKB:O14680 xref: UniProtKB:O43272 xref: UniProtKB:Q0P507 xref: UniProtKB:Q147W8 xref: UniProtKB:Q504W1 xref: UniProtKB:Q59FI8 xref: UniProtKB:Q6NV86 xref: UniProtKB:Q9UF13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019515 ! PRODH_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001030 ! proline dehydrogenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:P0000838 ! induction of apoptosis by oxidative stress [Term] id: CCO:B0054466 name: SRGP2_HUMAN def: "SLIT-ROBO Rho GTPase-activating protein 3" [UniProtKB:O43295] synonym: "Mental disorder-associated GAP" EXACT [UniProtKB:O43295] synonym: "Rho GTPase-activating protein 14" EXACT [UniProtKB:O43295] synonym: "srGAP2" EXACT [UniProtKB:O43295] synonym: "srGAP3" EXACT [UniProtKB:O43295] synonym: "WAVE-associated Rac GTPase-activating protein" EXACT [UniProtKB:O43295] synonym: "WRP" EXACT [UniProtKB:O43295] xref: EMBL:AAN07095.1 xref: EMBL:AAN57784.1 xref: EMBL:BAA24841.2 xref: UniProtKB:O43295 xref: UniProtKB:Q8IX13 xref: UniProtKB:Q8IZV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020038 ! SRGAP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017463 ! tnik-srgap3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070923 ! SRGP2_HUMAN-Phosphoserine602 relationship: transforms_into CCO:B0070924 ! SRGP2_HUMAN-Phosphoserine1070 [Term] id: CCO:B0054467 name: ZN264_HUMAN def: "Zinc finger protein 264" [UniProtKB:O43296] xref: EMBL:AAF42766.1 xref: EMBL:BAA24842.2 xref: UniProtKB:O43296 xref: UniProtKB:Q9P1V0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020683 ! ZNF264_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072076 ! ZN264_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0072077 ! ZN264_HUMAN-Phosphotyrosine343 relationship: transforms_into CCO:B0072078 ! ZN264_HUMAN-Phosphotyrosine483 relationship: transforms_into CCO:B0072079 ! ZN264_HUMAN-Phosphotyrosine511 [Term] id: CCO:B0054468 name: ZBT43_HUMAN def: "Zinc finger and BTB domain-containing protein 43" [UniProtKB:O43298] synonym: "Zinc finger and BTB domain-containing protein 22B" EXACT [UniProtKB:O43298] synonym: "Zinc finger protein 297B" EXACT [UniProtKB:O43298] synonym: "ZnF-x" EXACT [UniProtKB:O43298] xref: EMBL:AAC05500.1 xref: EMBL:AAH08828.1 xref: EMBL:BAA24844.2 xref: UniProtKB:O43298 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020558 ! ZBTB43_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014976 ! znf297b-znf417 physical interaction relationship: participates_in CCO:I0015057 ! arrb1-znf297b physical interaction relationship: participates_in CCO:I0015214 ! tceb3b-znf297b physical interaction relationship: participates_in CCO:I0015255 ! lmo3-znf297b physical interaction relationship: participates_in CCO:I0015322 ! traf2-znf297b physical interaction relationship: participates_in CCO:I0015539 ! lnx-znf297b physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054469 name: ADCY6_HUMAN def: "Adenylate cyclase type 6" [UniProtKB:O43306] synonym: "Adenylate cyclase type VI" EXACT [UniProtKB:O43306] synonym: "Adenylyl cyclase 6" EXACT [UniProtKB:O43306] synonym: "ATP pyrophosphate-lyase 6" EXACT [UniProtKB:O43306] synonym: "Ca(2+)-inhibitable adenylyl cyclase" EXACT [UniProtKB:O43306] synonym: "EC 4.6.1.1" EXACT [UniProtKB:O43306] xref: EMBL:AAF82478.1 xref: EMBL:AAH64923.1 xref: EMBL:BAA24852.2 xref: UniProtKB:O43306 xref: UniProtKB:Q9NR75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016912 ! ADCY6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019084 ! atxn1-adcy6 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0065405 ! ADCY6_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0065406 ! ADCY6_HUMAN-Phosphoserine576 [Term] id: CCO:B0054470 name: ZSC12_HUMAN def: "Zinc finger and SCAN domain-containing protein 12" [UniProtKB:O43309] synonym: "Zinc finger protein 305" EXACT [UniProtKB:O43309] synonym: "Zinc finger protein 96" EXACT [UniProtKB:O43309] xref: EMBL:AAH41661.1 xref: EMBL:BAA24856.2 xref: EMBL:CAB11428.2 xref: UniProtKB:O43309 xref: UniProtKB:O43724 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021000 ! ZSCAN12_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054471 name: PAX4_HUMAN def: "Paired box protein Pax-4" [UniProtKB:O43316] xref: EMBL:AAD02289.1 xref: EMBL:AAH74761.1 xref: EMBL:BAA24506.1 xref: UniProtKB:O43316 xref: UniProtKB:O95161 xref: UniProtKB:Q6B0H0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019308 ! PAX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054472 name: MCA3_HUMAN def: "Eukaryotic translation elongation factor 1 epsilon-1" [UniProtKB:O43324] synonym: "Elongation factor p18" EXACT [UniProtKB:O43324] synonym: "Multisynthetase complex auxiliary component p18" EXACT [UniProtKB:O43324] xref: EMBL:AAC39916.1 xref: EMBL:AAH05291.1 xref: EMBL:AAP35970.1 xref: EMBL:BAA24926.1 xref: EMBL:CAH72539.1 xref: EMBL:CAI14747.1 xref: EMBL:CAI21644.1 xref: UniProtKB:O43324 xref: UniProtKB:Q5THS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018581 ! EEF1E1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002227 ! positive regulation of DNA damage response, signal transduction by p53 class mediator relationship: transforms_into CCO:B0068044 ! MCA3_HUMAN-N-acetylalanine2 [Term] id: CCO:B0054473 name: ZN208_HUMAN def: "Zinc finger protein 208" [UniProtKB:O43345] xref: EMBL:AAB94784.1 xref: UniProtKB:O43345 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020654 ! ZNF208_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054474 name: ZN749_HUMAN def: "Zinc finger protein 749" [UniProtKB:O43361] xref: EMBL:AAB97932.1 xref: UniProtKB:O43361 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020924 ! ZNF749_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054475 name: HXA2_HUMAN def: "Homeobox protein Hox-A2" [UniProtKB:O43364] xref: EMBL:AAI30572.1 xref: EMBL:AAS00375.1 xref: EMBL:EAL24227.1 xref: EMBL:EAW93864.1 xref: UniProtKB:A1L4K3 xref: UniProtKB:O43364 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018179 ! HOXA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054476 name: HXA3_HUMAN def: "Homeobox protein Hox-A3" [UniProtKB:O43365] synonym: "Hox-1E" EXACT [UniProtKB:O43365] xref: EMBL:AAH15180.1 xref: EMBL:AAS00376.1 xref: UniProtKB:O43365 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018180 ! HOXA3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054477 name: O43372_HUMAN def: "WUGSC:H_DJ0320J15.1 protein (HCG1645130)" [UniProtKB:O43372] xref: EMBL:AAB97938.1 xref: EMBL:EAX02715.1 xref: UniProtKB:O43372 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021065 ! WUGSC:H_DJ0320J15.1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054478 name: RASL2_HUMAN def: "Ras GTPase-activating protein 4" [UniProtKB:O43374] synonym: "Calcium-promoted Ras inactivator" EXACT [UniProtKB:O43374] synonym: "Ras p21 protein activator 4" EXACT [UniProtKB:O43374] synonym: "RasGAP-activating-like protein 2" EXACT [UniProtKB:O43374] xref: EMBL:AAB97935.2 xref: EMBL:AAI13664.1 xref: EMBL:AAK31582.1 xref: EMBL:AAP22345.1 xref: EMBL:BAA25464.2 xref: UniProtKB:O43374 xref: UniProtKB:O60286 xref: UniProtKB:Q14CQ4 xref: UniProtKB:Q86UW3 xref: UniProtKB:Q96QU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019630 ! RASA4_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020647 ! rasa4-c16orf34 physical interaction relationship: participates_in CCO:I0020648 ! rasa4-apmap physical interaction relationship: participates_in CCO:I0020649 ! rasa4-erbb3 physical interaction relationship: participates_in CCO:I0020650 ! rasa4-ovgp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054479 name: O43392_HUMAN def: "Aryl hydrocarbon receptor nuclear translocator" [UniProtKB:O43392] xref: EMBL:AAC03365.1 xref: UniProtKB:O43392 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004099 ! ARNT_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054480 name: P52K_HUMAN def: "52 kDa repressor of the inhibitor of the protein kinase" [UniProtKB:O43422] synonym: "58 kDa interferon-induced protein kinase-interacting protein" EXACT [UniProtKB:O43422] synonym: "Death-associated protein 4" EXACT [UniProtKB:O43422] synonym: "P52rIPK" EXACT [UniProtKB:O43422] synonym: "p58IPK-interacting protein" EXACT [UniProtKB:O43422] synonym: "THAP domain-containing protein 0" EXACT [UniProtKB:O43422] xref: EMBL:AAC39564.1 xref: EMBL:AAG01570.1 xref: EMBL:AAH21992.1 xref: EMBL:AAI17139.1 xref: EMBL:AAI17141.1 xref: EMBL:CAB43226.1 xref: UniProtKB:O43422 xref: UniProtKB:Q17RY9 xref: UniProtKB:Q8WTW1 xref: UniProtKB:Q9Y3Z4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019277 ! PRKRIR_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0054481 name: GRID2_HUMAN def: "Glutamate receptor delta-2 subunit precursor" [UniProtKB:O43424] synonym: "GluR delta-2" EXACT [UniProtKB:O43424] xref: EMBL:AAC39579.1 xref: UniProtKB:O43424 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018064 ! GRID2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001695 ! glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000750 ! glutamate signaling pathway [Term] id: CCO:B0054482 name: MTG8R_HUMAN def: "Protein CBFA2T2" [UniProtKB:O43439] synonym: "ETO homologous on chromosome 20" EXACT [UniProtKB:O43439] synonym: "MTG8-like protein" EXACT [UniProtKB:O43439] synonym: "MTG8-related protein 1" EXACT [UniProtKB:O43439] synonym: "Myeloid translocation-related protein 1" EXACT [UniProtKB:O43439] synonym: "p85" EXACT [UniProtKB:O43439] xref: EMBL:AAC17499.1 xref: EMBL:AAC19378.1 xref: EMBL:AAC39841.1 xref: EMBL:AAC64699.1 xref: EMBL:AAD02825.1 xref: EMBL:AAD41221.1 xref: EMBL:AAH15066.1 xref: EMBL:AAH16298.2 xref: EMBL:AAH40344.1 xref: EMBL:CAI22125.1 xref: UniProtKB:O43439 xref: UniProtKB:Q5TGE4 xref: UniProtKB:Q5TGE7 xref: UniProtKB:Q8IWF3 xref: UniProtKB:Q96B06 xref: UniProtKB:Q96L00 xref: UniProtKB:Q9H436 xref: UniProtKB:Q9UJP8 xref: UniProtKB:Q9UJP9 xref: UniProtKB:Q9UP24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018678 ! CBFA2T2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015435 ! c8orf32-cbfa2t2 physical interaction relationship: participates_in CCO:I0015696 ! cbfa2t2-mdfi physical interaction relationship: participates_in CCO:I0017804 ! cbfa2t2-znf652-3 physical interaction relationship: participates_in CCO:I0018920 ! atn1-cbfa2t2 physical interaction relationship: participates_in CCO:I0018929 ! atn1-cbfa2t2-1 physical interaction relationship: participates_in CCO:I0019158 ! rere-cbfa2t2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068317 ! MTG8R_HUMAN-Phosphoserine33 [Term] id: CCO:B0054483 name: KLF4_HUMAN def: "Krueppel-like factor 4" [UniProtKB:O43474] synonym: "Epithelial zinc finger protein EZF" EXACT [UniProtKB:O43474] synonym: "Gut-enriched krueppel-like factor" EXACT [UniProtKB:O43474] xref: EMBL:AAB48399.1 xref: EMBL:AAC03462.1 xref: EMBL:AAD42165.1 xref: EMBL:AAH29923.1 xref: EMBL:ABG25917.1 xref: EMBL:CAI12253.1 xref: EMBL:CAI12254.1 xref: EMBL:EAW59020.1 xref: EMBL:EAW59021.1 xref: UniProtKB:O43474 xref: UniProtKB:P78338 xref: UniProtKB:Q5T3J8 xref: UniProtKB:Q5T3J9 xref: UniProtKB:Q9UNP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018419 ! KLF4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0054484 name: TNF12_HUMAN def: "Tumor necrosis factor ligand superfamily member 12" [UniProtKB:O43508] synonym: "APO3 ligand" EXACT [UniProtKB:O43508] synonym: "TNF-related weak inducer of apoptosis" EXACT [UniProtKB:O43508] synonym: "TWEAK" EXACT [UniProtKB:O43508] xref: EMBL:AAC39724.1 xref: EMBL:AAC51923.1 xref: EMBL:AAH19047.1 xref: EMBL:AAQ89229.1 xref: UniProtKB:O43508 xref: UniProtKB:Q8WUZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020299 ! TNFSF12_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054485 name: AT8B1_HUMAN def: "Probable phospholipid-transporting ATPase IC" [UniProtKB:O43520] synonym: "ATPase class I type 8B member 1" EXACT [UniProtKB:O43520] synonym: "EC 3.6.3.1" EXACT [UniProtKB:O43520] synonym: "Familial intrahepatic cholestasis type 1" EXACT [UniProtKB:O43520] xref: EMBL:AAC04328.1 xref: EMBL:AAC63461.1 xref: EMBL:AAH03534.1 xref: UniProtKB:O43520 xref: UniProtKB:Q9BTP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017092 ! ATP8B1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000490 ! phospholipid-translocating ATPase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0054486 name: O43532_HUMAN def: "RIG-like 7-1" [UniProtKB:O43532] xref: EMBL:AAB92664.1 xref: UniProtKB:O43532 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0054487 name: O43535_HUMAN def: "Cell matrix adhesion regulator variant" [UniProtKB:O43535] xref: EMBL:AAC02429.1 xref: UniProtKB:O43535 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021066 ! CMAR_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001245 ! regulation of cell adhesion [Term] id: CCO:B0054488 name: SMAD6_HUMAN def: "Mothers against decapentaplegic homolog 6" [UniProtKB:O43541] synonym: "hSMAD6" EXACT [UniProtKB:O43541] synonym: "Mothers against DPP homolog 6" EXACT [UniProtKB:O43541] synonym: "SMAD 6" EXACT [UniProtKB:O43541] synonym: "Smad6" EXACT [UniProtKB:O43541] xref: EMBL:AAB94137.1 xref: EMBL:AAC00497.1 xref: EMBL:AAC50792.1 xref: EMBL:AAC82331.1 xref: EMBL:AAF06841.1 xref: EMBL:AAF14343.1 xref: EMBL:AAH12986.1 xref: EMBL:AAH52569.1 xref: EMBL:CAP20377.1 xref: UniProtKB:A9J6M5 xref: UniProtKB:O43541 xref: UniProtKB:O43654 xref: UniProtKB:Q15799 xref: UniProtKB:Q7Z7L4 xref: UniProtKB:Q96E31 xref: UniProtKB:Q9UKZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019941 ! SMAD6_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004503 ! transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0018094 ! smad6-runx2-3 physical interaction relationship: participates_in CCO:I0018238 ! smad6-runx2 physical interaction relationship: participates_in CCO:I0018240 ! smad6-runx2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: transforms_into CCO:B0070606 ! SMAD6_HUMAN-Phosphoserine435 [Term] id: CCO:B0054489 name: GON2_HUMAN def: "Progonadoliberin-2 precursor" [UniProtKB:O43555] synonym: "Progonadoliberin II" EXACT [UniProtKB:O43555] xref: EMBL:AAC02980.1 xref: EMBL:AAC02981.1 xref: EMBL:AAH69362.1 xref: EMBL:AAI15401.1 xref: EMBL:CAC10338.1 xref: EMBL:CAC29100.1 xref: EMBL:CAC29101.1 xref: UniProtKB:O43555 xref: UniProtKB:Q14C68 xref: UniProtKB:Q9BYN9 xref: UniProtKB:Q9BYP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017950 ! GNRH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066514 ! GON2_HUMAN-Pyrrolidone carboxylic acid24 relationship: transforms_into CCO:B0066515 ! GON2_HUMAN-Glycine amide33 [Term] id: CCO:B0054490 name: TNF14_HUMAN def: "Tumor necrosis factor ligand superfamily member 14" [UniProtKB:O43557] synonym: "CD258 antigen" EXACT [UniProtKB:O43557] synonym: "Herpesvirus entry mediator-ligand" EXACT [UniProtKB:O43557] synonym: "HVEM-L" EXACT [UniProtKB:O43557] xref: EMBL:AAC25169.1 xref: EMBL:AAC39563.1 xref: EMBL:AAK26160.1 xref: EMBL:AAQ89171.1 xref: UniProtKB:O43557 xref: UniProtKB:O75476 xref: UniProtKB:Q8WVF8 xref: UniProtKB:Q96LD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020301 ! TNFSF14_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005787 ! caspase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016115 ! hvem-light physical interaction relationship: participates_in CCO:I0016260 ! tr6-light physical interaction relationship: participates_in CCO:I0016261 ! light-tr6 physical interaction relationship: participates_in CCO:I0016262 ! light-lt_beta-r physical interaction relationship: participates_in CCO:I0016263 ! light-hvem physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000825 ! release of cytoplasmic sequestered NF-kappaB relationship: participates_in CCO:P0001401 ! T cell costimulation relationship: participates_in CCO:P0002039 ! T cell proliferation [Term] id: CCO:B0054491 name: FRS3_HUMAN def: "Fibroblast growth factor receptor substrate 3" [UniProtKB:O43559] synonym: "FGFR substrate 3" EXACT [UniProtKB:O43559] synonym: "FGFR-signaling adaptor SNT2" EXACT [UniProtKB:O43559] synonym: "SNT-2" EXACT [UniProtKB:O43559] synonym: "Suc1-associated neurotrophic factor target 2" EXACT [UniProtKB:O43559] xref: EMBL:AAB92555.1 xref: EMBL:AAH10611.1 xref: EMBL:CAG33307.1 xref: EMBL:CAI13183.1 xref: EMBL:CAI13184.1 xref: UniProtKB:O43559 xref: UniProtKB:Q5T3D5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017835 ! FRS3_human relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020579 ! kars-frs3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0054492 name: LAT_HUMAN def: "Linker for activation of T-cells family member 1" [UniProtKB:O43561] synonym: "36 kDa phospho-tyrosine adapter protein" EXACT [UniProtKB:O43561] synonym: "p36-38" EXACT [UniProtKB:O43561] synonym: "pp36" EXACT [UniProtKB:O43561] xref: EMBL:AAC39636.1 xref: EMBL:AAC39637.1 xref: EMBL:AAH11563.1 xref: EMBL:CAA11218.1 xref: UniProtKB:O43561 xref: UniProtKB:O43919 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018457 ! LAT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002981 ! regulation of T cell activation relationship: transforms_into CCO:B0067580 ! LAT_HUMAN-Phosphothreonine39 relationship: transforms_into CCO:B0067581 ! LAT_HUMAN-Phosphoserine84 relationship: transforms_into CCO:B0067582 ! LAT_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0067583 ! LAT_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0067584 ! LAT_HUMAN-Phosphotyrosine110 relationship: transforms_into CCO:B0067585 ! LAT_HUMAN-Phosphotyrosine156 relationship: transforms_into CCO:B0067586 ! LAT_HUMAN-Phosphotyrosine161 relationship: transforms_into CCO:B0067587 ! LAT_HUMAN-Phosphotyrosine200 relationship: transforms_into CCO:B0067588 ! LAT_HUMAN-Phosphotyrosine220 relationship: transforms_into CCO:B0067589 ! LAT_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0067590 ! LAT_HUMAN-Phosphotyrosine255 [Term] id: CCO:B0054493 name: AKA10_HUMAN def: "A kinase anchor protein 10, mitochondrial precursor" [UniProtKB:O43572] synonym: "D-AKAP-2" EXACT [UniProtKB:O43572] synonym: "Dual specificity A kinase-anchoring protein 2" EXACT [UniProtKB:O43572] synonym: "PRKA10" EXACT [UniProtKB:O43572] synonym: "Protein kinase A-anchoring protein 10" EXACT [UniProtKB:O43572] xref: EMBL:AAB92260.1 xref: EMBL:AAH17055.1 xref: UniProtKB:O43572 xref: UniProtKB:Q96AJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016939 ! AKAP10_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015823 ! akap10-prkar1a physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054494 name: O43582_HUMAN def: "Best's macular dystrophy related protein" [UniProtKB:O43582] xref: EMBL:AAB92668.1 xref: UniProtKB:O43582 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054495 name: HAIR_HUMAN def: "Protein hairless" [UniProtKB:O43593] xref: EMBL:AAC32258.3 xref: EMBL:AAH67128.1 xref: EMBL:CAB86602.1 xref: EMBL:CAB87577.2 xref: UniProtKB:O43593 xref: UniProtKB:Q6GS30 xref: UniProtKB:Q96H33 xref: UniProtKB:Q9NPE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018101 ! HR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054496 name: O43594_HUMAN def: "Ku86 autoantigen related protein 1" [UniProtKB:O43594] xref: EMBL:AAC52087.1 xref: UniProtKB:O43594 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021067 ! KARP-1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000643 ! regulation of DNA repair [Term] id: CCO:B0054497 name: RCL_HUMAN def: "c-Myc-responsive protein Rcl" [UniProtKB:O43598] xref: EMBL:AAB96766.1 xref: EMBL:AAH11683.1 xref: EMBL:CAI20205.1 xref: UniProtKB:O43598 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019658 ! RCL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015437 ! rcl-rcl physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0069842 ! RCL_HUMAN-Phosphoserine169 [Term] id: CCO:B0054498 name: GALR2_HUMAN def: "Galanin receptor type 2" [UniProtKB:O43603] synonym: "GAL2-R" EXACT [UniProtKB:O43603] synonym: "GALR2" EXACT [UniProtKB:O43603] xref: EMBL:AAC18118.1 xref: EMBL:AAC36587.1 xref: EMBL:AAC39634.1 xref: EMBL:AAD08671.1 xref: EMBL:AAH69130.1 xref: EMBL:AAH74914.1 xref: EMBL:AAH74915.1 xref: EMBL:AAI09052.1 xref: EMBL:AAI09053.1 xref: UniProtKB:O43603 xref: UniProtKB:Q32MN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017862 ! GALR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001307 ! galanin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: transforms_into CCO:B0066363 ! GALR2_HUMAN-Phosphotyrosine213 [Term] id: CCO:B0054499 name: SPY1_HUMAN def: "Protein sprouty homolog 1" [UniProtKB:O43609] synonym: "Spry-1" EXACT [UniProtKB:O43609] xref: EMBL:AAC39566.1 xref: EMBL:AAH63856.1 xref: EMBL:AAP20102.1 xref: EMBL:AAT06102.1 xref: UniProtKB:O43609 xref: UniProtKB:Q6PNE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020028 ! SPRY1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0070842 ! SPY1_HUMAN-Phosphotyrosine53 [Term] id: CCO:B0054500 name: SPY3_HUMAN def: "Protein sprouty homolog 3" [UniProtKB:O43610] synonym: "Spry-3" EXACT [UniProtKB:O43610] xref: EMBL:AAC39567.1 xref: EMBL:AAH69609.1 xref: EMBL:AAH74972.1 xref: EMBL:AAH74973.1 xref: EMBL:CAB96768.1 xref: UniProtKB:O43610 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020029 ! SPRY3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0054501 name: OREX_HUMAN def: "Orexin precursor" [UniProtKB:O43612] synonym: "Hcrt" EXACT [UniProtKB:O43612] synonym: "Hypocretin" EXACT [UniProtKB:O43612] xref: EMBL:AAC39600.1 xref: EMBL:AAD24459.1 xref: UniProtKB:O43612 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019240 ! HCRT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017957 ! hcrt-hla_dqa1-1 physical interaction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0068992 ! OREX_HUMAN-Pyrrolidone carboxylic acid34 relationship: transforms_into CCO:B0068993 ! OREX_HUMAN-Leucine amide66 relationship: transforms_into CCO:B0068994 ! OREX_HUMAN-Methionine amide97 [Term] id: CCO:B0054502 name: OX1R_HUMAN def: "Orexin receptor type 1" [UniProtKB:O43613] synonym: "Hypocretin receptor type 1" EXACT [UniProtKB:O43613] synonym: "Ox1r" EXACT [UniProtKB:O43613] xref: EMBL:AAC39601.1 xref: EMBL:AAG28020.1 xref: EMBL:AAH74796.1 xref: EMBL:AAL47214.1 xref: EMBL:AAL50221.1 xref: EMBL:EAX07602.1 xref: UniProtKB:O43613 xref: UniProtKB:Q9HBV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019250 ! HCRTR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0069007 ! OX1R_HUMAN-Phosphotyrosine27 [Term] id: CCO:B0054503 name: OX2R_HUMAN def: "Orexin receptor type 2" [UniProtKB:O43614] synonym: "Hypocretin receptor type 2" EXACT [UniProtKB:O43614] synonym: "Ox2r" EXACT [UniProtKB:O43614] xref: EMBL:AAC39602.1 xref: EMBL:AAL47215.1 xref: EMBL:CAH73407.1 xref: EMBL:CAI19665.1 xref: EMBL:EAX04440.1 xref: UniProtKB:O43614 xref: UniProtKB:Q5VTM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019252 ! HCRTR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_function CCO:F0003180 ! orexin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054504 name: SNAI2_HUMAN def: "Zinc finger protein SNAI2" [UniProtKB:O43623] synonym: "Neural crest transcription factor Slug" EXACT [UniProtKB:O43623] synonym: "Protein snail homolog 2" EXACT [UniProtKB:O43623] xref: EMBL:AAC34288.1 xref: EMBL:AAD55240.1 xref: EMBL:AAH14890.1 xref: EMBL:AAH15895.1 xref: UniProtKB:O43623 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019960 ! SNAI2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054505 name: O43627_HUMAN def: "Olfactory receptor-like protein" [UniProtKB:O43627] xref: EMBL:AAB97432.1 xref: UniProtKB:O43627 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021068 ! OR2H5P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054506 name: NCK2_HUMAN def: "Cytoplasmic protein NCK2" [UniProtKB:O43639] synonym: "NCK adaptor protein 2" EXACT [UniProtKB:O43639] synonym: "Nck-2" EXACT [UniProtKB:O43639] synonym: "SH2/SH3 adaptor protein NCK-beta" EXACT [UniProtKB:O43639] xref: EMBL:AAC04831.1 xref: EMBL:AAC80284.1 xref: EMBL:AAH00103.1 xref: EMBL:AAH07195.1 xref: UniProtKB:O43639 xref: UniProtKB:Q9BWN9 xref: UniProtKB:Q9UIC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018726 ! NCK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015366 ! abi2-nck2 physical interaction relationship: participates_in CCO:I0015388 ! nck2-trip6 physical interaction relationship: participates_in CCO:I0015504 ! nck2-nckipsd physical interaction relationship: participates_in CCO:I0015612 ! nck2-sf3b4 physical interaction relationship: participates_in CCO:I0015693 ! nck2-wbp11 physical interaction relationship: participates_in CCO:I0015816 ! flj12529-nck2 physical interaction relationship: participates_in CCO:I0015836 ! hnrpk-nck2 physical interaction relationship: participates_in CCO:I0015995 ! nphs1-nck2 physical interaction relationship: participates_in CCO:I0015996 ! nphs1-nck2-1 colocalization relationship: participates_in CCO:I0017552 ! nck2-atn1 physical interaction relationship: participates_in CCO:I0019771 ! nck2-eef1g physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000718 ! regulation of epidermal growth factor receptor activity relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001331 ! positive regulation of actin filament polymerization relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: transforms_into CCO:B0068465 ! NCK2_HUMAN-Phosphothreonine92 relationship: transforms_into CCO:B0068466 ! NCK2_HUMAN-Phosphotyrosine110 [Term] id: CCO:B0054507 name: O43649_HUMAN def: "Lymphocyte-specific protein 1" [UniProtKB:O43649] xref: EMBL:AAC00494.1 xref: UniProtKB:O43649 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018526 ! LSP1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054508 name: TSN6_HUMAN def: "Tetraspanin-6" [UniProtKB:O43657] synonym: "A15 homolog" EXACT [UniProtKB:O43657] synonym: "T245 protein" EXACT [UniProtKB:O43657] synonym: "Tetraspanin TM4-D" EXACT [UniProtKB:O43657] synonym: "Transmembrane 4 superfamily member 6" EXACT [UniProtKB:O43657] synonym: "Tspan-6" EXACT [UniProtKB:O43657] xref: EMBL:AAC64257.1 xref: EMBL:AAC69710.1 xref: EMBL:AAD00560.1 xref: EMBL:AAF08365.1 xref: EMBL:AAH12389.1 xref: EMBL:AAP35623.1 xref: EMBL:AAQ89184.1 xref: EMBL:CAB55681.1 xref: UniProtKB:O43657 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020375 ! TSPAN6_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054509 name: ZN207_HUMAN def: "Zinc finger protein 207" [UniProtKB:O43670] xref: EMBL:AAC78561.1 xref: EMBL:AAH02372.1 xref: EMBL:AAH08023.1 xref: UniProtKB:O43670 xref: UniProtKB:Q96HW5 xref: UniProtKB:Q9BUQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020653 ! ZNF207_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054510 name: TCF21_HUMAN def: "Transcription factor 21" [UniProtKB:O43680] synonym: "Capsulin" EXACT [UniProtKB:O43680] synonym: "Epicardin" EXACT [UniProtKB:O43680] synonym: "Pod-1" EXACT [UniProtKB:O43680] synonym: "Podocyte-expressed 1" EXACT [UniProtKB:O43680] xref: EMBL:AAC62514.1 xref: EMBL:AAC62532.1 xref: EMBL:AAH25697.1 xref: EMBL:AAV38466.1 xref: EMBL:CAC26822.1 xref: UniProtKB:O43545 xref: UniProtKB:O43680 xref: UniProtKB:Q9BZ14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020214 ! TCF21_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020475 ! tcf21-aplp1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054511 name: AKA7A_HUMAN def: "A-kinase anchor protein 7 isoforms alpha and beta" [UniProtKB:O43687] synonym: "A-kinase anchor protein 18" EXACT [UniProtKB:O43687] synonym: "Protein kinase A-anchoring protein 7 isoforms alpha/beta" EXACT [UniProtKB:O43687] xref: EMBL:AAC39715.1 xref: EMBL:AAF26676.1 xref: EMBL:AAH16927.1 xref: EMBL:AAH73847.1 xref: EMBL:AAH94732.1 xref: EMBL:CAI19001.1 xref: EMBL:CAI19002.1 xref: EMBL:CAI21507.1 xref: EMBL:CAI21508.1 xref: UniProtKB:O43687 xref: UniProtKB:Q5TBR9 xref: UniProtKB:Q5TBS0 xref: UniProtKB:Q9HCZ8 xref: UniProtKB:Q9P0G4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016942 ! AKAP7_human relationship: has_function CCO:F0008036 ! protein kinase A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000783 ! lateral plasma membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054512 name: TLX3_HUMAN def: "T-cell leukemia homeobox protein 3" [UniProtKB:O43711] synonym: "Homeobox protein Hox-11L2" EXACT [UniProtKB:O43711] xref: EMBL:AAH17291.1 xref: EMBL:CAA11550.1 xref: UniProtKB:O43711 xref: UniProtKB:Q96AD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020287 ! TLX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation [Term] id: CCO:B0054513 name: GATCL_HUMAN def: "GatC-like protein" [UniProtKB:O43716] synonym: "Protein 15E1.2" EXACT [UniProtKB:O43716] xref: EMBL:AAI07146.1 xref: EMBL:AAI07147.1 xref: EMBL:CAA16496.1 xref: UniProtKB:O43716 xref: UniProtKB:Q3B824 xref: UniProtKB:Q3KNR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017874 ! GATC_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000665 ! regulation of translational fidelity [Term] id: CCO:B0054514 name: HTSF1_HUMAN def: "HIV Tat-specific factor 1" [UniProtKB:O43719] synonym: "Tat-SF1" EXACT [UniProtKB:O43719] xref: EMBL:AAB18823.1 xref: EMBL:AAH09896.1 xref: EMBL:AAP35532.1 xref: EMBL:BAD92540.1 xref: EMBL:CAB10730.1 xref: UniProtKB:O43719 xref: UniProtKB:Q59G06 xref: UniProtKB:Q99730 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018172 ! HTATSF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020337 ! htatsf1-fez1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0066941 ! HTSF1_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0066942 ! HTSF1_HUMAN-Phosphoserine481 relationship: transforms_into CCO:B0066943 ! HTSF1_HUMAN-Phosphoserine494 relationship: transforms_into CCO:B0066944 ! HTSF1_HUMAN-Phosphoserine498 relationship: transforms_into CCO:B0066945 ! HTSF1_HUMAN-Phosphoserine557 relationship: transforms_into CCO:B0066946 ! HTSF1_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0066947 ! HTSF1_HUMAN-Phosphoserine579 relationship: transforms_into CCO:B0066948 ! HTSF1_HUMAN-Phosphoserine597 relationship: transforms_into CCO:B0066949 ! HTSF1_HUMAN-Phosphoserine600 relationship: transforms_into CCO:B0066950 ! HTSF1_HUMAN-Phosphoserine607 relationship: transforms_into CCO:B0066951 ! HTSF1_HUMAN-Phosphoserine616 relationship: transforms_into CCO:B0066952 ! HTSF1_HUMAN-Phosphoserine624 relationship: transforms_into CCO:B0066953 ! HTSF1_HUMAN-Phosphoserine642 relationship: transforms_into CCO:B0066954 ! HTSF1_HUMAN-Phosphoserine676 relationship: transforms_into CCO:B0066955 ! HTSF1_HUMAN-Phosphoserine702 relationship: transforms_into CCO:B0066956 ! HTSF1_HUMAN-Phosphoserine713 relationship: transforms_into CCO:B0066957 ! HTSF1_HUMAN-Phosphoserine714 relationship: transforms_into CCO:B0066958 ! HTSF1_HUMAN-Phosphoserine721 [Term] id: CCO:B0054515 name: CIKS_HUMAN def: "Adapter protein CIKS" [UniProtKB:O43734] synonym: "ACT1" EXACT [UniProtKB:O43734] synonym: "Connection to IKK and SAPK/JNK" EXACT [UniProtKB:O43734] synonym: "Nuclear factor NF-kappa-B activator 1" EXACT [UniProtKB:O43734] synonym: "TRAF3-interacting protein 2" EXACT [UniProtKB:O43734] xref: EMBL:AAF67445.1 xref: EMBL:AAF67446.1 xref: EMBL:AAF67447.1 xref: EMBL:AAG15367.1 xref: EMBL:AAG15407.1 xref: EMBL:AAH02823.1 xref: EMBL:BAB15117.1 xref: EMBL:BAB15507.1 xref: EMBL:CAA15506.1 xref: EMBL:CAA15507.1 xref: EMBL:CAB43390.1 xref: EMBL:CAD92596.1 xref: EMBL:CAI22298.1 xref: UniProtKB:O43734 xref: UniProtKB:Q5R3A3 xref: UniProtKB:Q7Z6Q3 xref: UniProtKB:Q9H5W2 xref: UniProtKB:Q9H6Y3 xref: UniProtKB:Q9NS14 xref: UniProtKB:Q9UG72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017365 ! TRAF3IP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0015141 ! c6orf4-traf2 physical interaction relationship: participates_in CCO:I0015335 ! c6orf4-mdfi physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054516 name: CYH3_HUMAN def: "Cytohesin-3" [UniProtKB:O43739] synonym: "ARF nucleotide-binding site opener 3" EXACT [UniProtKB:O43739] synonym: "General receptor of phosphoinositides 1" EXACT [UniProtKB:O43739] synonym: "Grp1" EXACT [UniProtKB:O43739] synonym: "PH, SEC7 and coiled-coil domain-containing protein 3" EXACT [UniProtKB:O43739] synonym: "Protein ARNO3" EXACT [UniProtKB:O43739] xref: EMBL:AAH28717.1 xref: EMBL:CAA06434.1 xref: EMBL:CAA11686.1 xref: UniProtKB:O43739 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017511 ! CYTH3_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_function CCO:F0001708 ! inositol-1,4,5-triphosphate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0015010 ! cnksr1-pscd3 physical interaction relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0054517 name: AAKB2_HUMAN def: "5'-AMP-activated protein kinase subunit beta-2" [UniProtKB:O43741] synonym: "AMPK beta-2 chain" EXACT [UniProtKB:O43741] xref: EMBL:AAH53610.1 xref: EMBL:AAM74153.1 xref: EMBL:CAA12030.1 xref: EMBL:CAH72644.1 xref: UniProtKB:O43741 xref: UniProtKB:Q5VXY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016866 ! PRKAB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation relationship: transforms_into CCO:B0065240 ! AAKB2_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0065241 ! AAKB2_HUMAN-Phosphoserine183 [Term] id: CCO:B0054518 name: OR1F1_HUMAN def: "Olfactory receptor 1F1" [UniProtKB:O43749] synonym: "Olfactory receptor 16-35" EXACT [UniProtKB:O43749] synonym: "Olfactory receptor OR16-4" EXACT [UniProtKB:O43749] synonym: "OR16-35" EXACT [UniProtKB:O43749] xref: EMBL:AAC39614.1 xref: EMBL:AAH69335.1 xref: EMBL:AAK95044.1 xref: EMBL:BAC06122.1 xref: EMBL:CAA05903.1 xref: EMBL:CAA74794.1 xref: EMBL:DAA04645.1 xref: UniProtKB:O15246 xref: UniProtKB:O43749 xref: UniProtKB:Q6IFL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019064 ! OR1F1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054519 name: TLX2_HUMAN def: "T-cell leukemia homeobox protein 2" [UniProtKB:O43763] synonym: "Homeobox protein Hox-11L1" EXACT [UniProtKB:O43763] synonym: "Neural crest homeobox protein" EXACT [UniProtKB:O43763] xref: EMBL:AAH06356.1 xref: EMBL:BAA83463.1 xref: EMBL:CAA05636.1 xref: UniProtKB:O43763 xref: UniProtKB:Q9UQ48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020286 ! TLX2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002952 ! negative regulation of dendrite morphogenesis [Term] id: CCO:B0054520 name: MCAT_HUMAN def: "Mitochondrial carnitine/acylcarnitine carrier protein" [UniProtKB:O43772] synonym: "CAC" EXACT [UniProtKB:O43772] synonym: "Carnitine/acylcarnitine translocase" EXACT [UniProtKB:O43772] synonym: "Solute carrier family 25 member 20" EXACT [UniProtKB:O43772] xref: EMBL:AAH01689.1 xref: EMBL:CAA71367.1 xref: EMBL:CAB55356.1 xref: UniProtKB:O43772 xref: UniProtKB:Q9UIQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018584 ! SLC25A20_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002697 ! acyl carnitine transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020665 ! slc25a20-c16orf34 physical interaction relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation relationship: transforms_into CCO:B0068052 ! MCAT_HUMAN-N6-acetyllysine148 relationship: transforms_into CCO:B0068053 ! MCAT_HUMAN-N6-acetyllysine244 [Term] id: CCO:B0054521 name: DUX1_HUMAN def: "Double homeobox protein 1" [UniProtKB:O43812] xref: EMBL:CAA04776.1 xref: UniProtKB:O43812 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017638 ! DUX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054522 name: ANGL7_HUMAN def: "Angiopoietin-related protein 7 precursor" [UniProtKB:O43827] synonym: "Angiopoietin-like 7" EXACT [UniProtKB:O43827] synonym: "Angiopoietin-like factor" EXACT [UniProtKB:O43827] synonym: "Cornea-derived transcript 6 protein" EXACT [UniProtKB:O43827] xref: EMBL:AAH01881.1 xref: EMBL:AAP88804.1 xref: EMBL:AAQ88668.1 xref: EMBL:AAY22173.1 xref: EMBL:CAA76078.1 xref: EMBL:CAB44734.1 xref: EMBL:CAC15571.1 xref: EMBL:CAI17229.1 xref: UniProtKB:O43827 xref: UniProtKB:Q4ZGK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016971 ! ANGPTL7_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054523 name: ZF161_HUMAN def: "Zinc finger protein 161 homolog" [UniProtKB:O43829] synonym: "HZF5" EXACT [UniProtKB:O43829] synonym: "Zfp-161" EXACT [UniProtKB:O43829] synonym: "Zinc finger and BTB domain-containing protein 14" EXACT [UniProtKB:O43829] synonym: "Zinc finger protein 5" EXACT [UniProtKB:O43829] xref: EMBL:AAI10520.1 xref: EMBL:BAA20131.1 xref: EMBL:CAA73258.1 xref: UniProtKB:O00403 xref: UniProtKB:O43829 xref: UniProtKB:Q2TB80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020581 ! ZFP161_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054524 name: ZNF73_HUMAN def: "Zinc finger protein 73" [UniProtKB:O43830] synonym: "hZNF2" EXACT [UniProtKB:O43830] synonym: "Zinc finger protein 186" EXACT [UniProtKB:O43830] xref: EMBL:CAA71860.1 xref: EMBL:CAC16146.1 xref: UniProtKB:O43830 xref: UniProtKB:Q9UC08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020983 ! ZNF73_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054525 name: O43831_HUMAN def: "NFX.1" [UniProtKB:O43831] xref: EMBL:AAB94787.1 xref: UniProtKB:O43831 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054526 name: NRDC_HUMAN def: "Nardilysin precursor" [UniProtKB:O43847] synonym: "EC 3.4.24.61" EXACT [UniProtKB:O43847] synonym: "N-arginine dibasic convertase" EXACT [UniProtKB:O43847] synonym: "NRD convertase" EXACT [UniProtKB:O43847] synonym: "NRD-C" EXACT [UniProtKB:O43847] xref: EMBL:AAC39597.1 xref: EMBL:AAH08775.1 xref: EMBL:CAA04025.1 xref: EMBL:CAA63694.1 xref: EMBL:CAA63698.1 xref: EMBL:CAH74100.1 xref: EMBL:CAI22216.1 xref: UniProtKB:O15241 xref: UniProtKB:O15242 xref: UniProtKB:O43847 xref: UniProtKB:Q5VUL0 xref: UniProtKB:Q96HB2 xref: UniProtKB:Q9NU57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018865 ! NRD1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003469 ! nardilysin activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007338 ! epidermal growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054527 name: O43851_HUMAN def: "PDE4C-delta109" [UniProtKB:O43851] xref: EMBL:AAB96878.1 xref: UniProtKB:O43851 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019340 ! PDE4C_human relationship: has_function CCO:F0000584 ! cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054528 name: OR2T1_HUMAN def: "Olfactory receptor 2T1" [UniProtKB:O43869] synonym: "Olfactory receptor 1-25" EXACT [UniProtKB:O43869] synonym: "Olfactory receptor OR1-61" EXACT [UniProtKB:O43869] synonym: "OR1-25" EXACT [UniProtKB:O43869] xref: EMBL:AAC39611.1 xref: EMBL:AAK95098.1 xref: EMBL:DAA04861.1 xref: UniProtKB:O43869 xref: UniProtKB:Q6IEZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019115 ! OR2T1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054529 name: O43898_HUMAN def: "High-affinity lysophosphatidic acid receptor homolog" [UniProtKB:O43898] xref: EMBL:AAB93884.1 xref: UniProtKB:O43898 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054530 name: TYOBP_HUMAN def: "TYRO protein tyrosine kinase-binding protein precursor" [UniProtKB:O43914] synonym: "DNAX-activation protein 12" EXACT [UniProtKB:O43914] synonym: "KAR-associated protein" EXACT [UniProtKB:O43914] synonym: "Killer-activating receptor-associated protein" EXACT [UniProtKB:O43914] xref: EMBL:AAD09436.1 xref: EMBL:AAD09437.1 xref: EMBL:AAH11175.1 xref: EMBL:AAL74017.1 xref: EMBL:AAP88853.1 xref: EMBL:CAB52288.1 xref: EMBL:CAG29338.1 xref: UniProtKB:O43914 xref: UniProtKB:Q9UMT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020394 ! TYROBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0071643 ! TYOBP_HUMAN-Phosphotyrosine91 relationship: transforms_into CCO:B0071644 ! TYOBP_HUMAN-Phosphotyrosine102 [Term] id: CCO:B0054531 name: AIRE_HUMAN def: "Autoimmune regulator" [UniProtKB:O43918] synonym: "APECED protein" EXACT [UniProtKB:O43918] synonym: "Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein" EXACT [UniProtKB:O43918] xref: EMBL:BAA23988.1 xref: EMBL:BAA23989.1 xref: EMBL:BAA23990.1 xref: EMBL:BAA23991.1 xref: EMBL:BAA23992.1 xref: EMBL:BAA23993.1 xref: EMBL:BAA95560.1 xref: EMBL:CAA08759.1 xref: EMBL:CAB10790.1 xref: UniProtKB:O43918 xref: UniProtKB:O43922 xref: UniProtKB:O43932 xref: UniProtKB:O75745 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016938 ! AIRE_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006094 ! translation regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054532 name: SSX4_HUMAN def: "Protein SSX4" [UniProtKB:O60224] synonym: "Cancer/testis antigen 5.4" EXACT [UniProtKB:O60224] synonym: "CT5.4" EXACT [UniProtKB:O60224] xref: EMBL:AAC05820.1 xref: EMBL:AAH05325.1 xref: EMBL:CAI40260.1 xref: EMBL:CAI40273.1 xref: UniProtKB:O60224 xref: UniProtKB:Q5JQZ0 xref: UniProtKB:Q9UJU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020051 ! SSX4_human relationship: encoded_by CCO:G0020052 ! SSX4B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015185 ! hif1a-ssx4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054533 name: SSX5_HUMAN def: "Protein SSX5" [UniProtKB:O60225] xref: EMBL:AAC05821.1 xref: EMBL:AAH16640.1 xref: EMBL:CAI40524.1 xref: EMBL:CAI41134.1 xref: UniProtKB:O60225 xref: UniProtKB:Q5JQ59 xref: UniProtKB:Q96AW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020053 ! SSX5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054534 name: KALRN_HUMAN def: "Kalirin" [UniProtKB:O60229] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O60229] synonym: "Huntingtin-associated protein-interacting protein" EXACT [UniProtKB:O60229] synonym: "Protein Duo" EXACT [UniProtKB:O60229] synonym: "Serine/threonine kinase with Dbl- and pleckstrin homology domain" EXACT [UniProtKB:O60229] xref: EMBL:AAC15791.1 xref: EMBL:AAH26865.1 xref: EMBL:AAH58015.1 xref: EMBL:BAA76314.1 xref: EMBL:BAC86373.1 xref: EMBL:BAD18530.1 xref: EMBL:CAB70850.1 xref: UniProtKB:A8MSI4 xref: UniProtKB:O60229 xref: UniProtKB:Q6ZN45 xref: UniProtKB:Q8TBQ5 xref: UniProtKB:Q9NSZ4 xref: UniProtKB:Q9Y2A5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018374 ! KALRN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017433 ! disc1-hapip physical interaction relationship: participates_in CCO:I0017434 ! mitap1-hapip physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0067251 ! KALRN_HUMAN-Phosphoserine1750 relationship: transforms_into CCO:B0067252 ! KALRN_HUMAN-Phosphoserine1753 relationship: transforms_into CCO:B0067253 ! KALRN_HUMAN-Phosphoserine1756 relationship: transforms_into CCO:B0067254 ! KALRN_HUMAN-Phosphoserine1773 relationship: transforms_into CCO:B0067255 ! KALRN_HUMAN-Phosphoserine1799 relationship: transforms_into CCO:B0067256 ! KALRN_HUMAN-Phosphoserine1817 relationship: transforms_into CCO:B0067257 ! KALRN_HUMAN-Phosphoserine2261 [Term] id: CCO:B0054535 name: MYPT2_HUMAN def: "Protein phosphatase 1 regulatory subunit 12B" [UniProtKB:O60237] synonym: "Myosin phosphatase target subunit 2" EXACT [UniProtKB:O60237] synonym: "Myosin phosphatase-targeting subunit 2" EXACT [UniProtKB:O60237] xref: EMBL:AAH34430.1 xref: EMBL:AAK00336.1 xref: EMBL:AAK00337.1 xref: EMBL:BAA28376.1 xref: EMBL:BAB17610.1 xref: EMBL:BAB17611.1 xref: EMBL:CAH73375.1 xref: EMBL:CAI15935.1 xref: UniProtKB:O60237 xref: UniProtKB:Q5VUK2 xref: UniProtKB:Q8N179 xref: UniProtKB:Q9HCB7 xref: UniProtKB:Q9HCB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018702 ! PPP1R12B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068418 ! MYPT2_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0068419 ! MYPT2_HUMAN-Phosphoserine947 [Term] id: CCO:B0054536 name: BAI3_HUMAN def: "Brain-specific angiogenesis inhibitor 3 precursor" [UniProtKB:O60242] xref: EMBL:AAI11721.1 xref: EMBL:BAA25363.1 xref: EMBL:BAA25476.2 xref: EMBL:CAC34969.2 xref: EMBL:CAH71522.1 xref: EMBL:CAH71772.1 xref: EMBL:CAH73864.1 xref: EMBL:CAI19625.1 xref: EMBL:CAI21673.1 xref: EMBL:EAW48837.1 xref: UniProtKB:O60242 xref: UniProtKB:O60297 xref: UniProtKB:Q2NKN6 xref: UniProtKB:Q5VY37 xref: UniProtKB:Q9BX54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017121 ! BAI3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0063708 ! BAI3_HUMAN-Phosphoserine1220 relationship: transforms_into CCO:B0063709 ! BAI3_HUMAN-Phosphoserine1411 [Term] id: CCO:B0054537 name: GBG7_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 precursor" [UniProtKB:O60262] xref: EMBL:AAC32595.1 xref: EMBL:AAH14466.1 xref: EMBL:AAH53630.1 xref: EMBL:AAM12588.1 xref: EMBL:BAA28348.1 xref: UniProtKB:O60262 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017889 ! GNG7_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020220 ! acp6-gng7 physical interaction relationship: participates_in CCO:I0020371 ! mpp3-gng7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000711 ! receptor guanylyl cyclase signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0054538 name: SMCA5_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5" [UniProtKB:O60264] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O60264] synonym: "hSNF2H" EXACT [UniProtKB:O60264] synonym: "Sucrose nonfermenting protein 2 homolog" EXACT [UniProtKB:O60264] synonym: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5" EXACT [UniProtKB:O60264] xref: EMBL:AAH23144.1 xref: EMBL:BAA25173.1 xref: UniProtKB:O60264 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019949 ! SMARCA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015970 ! hbxap-smarca5-3 direct interaction relationship: participates_in CCO:I0016152 ! baz1b-myo1c physical interaction relationship: participates_in CCO:I0016154 ! baz1b-smrca5 physical interaction relationship: participates_in CCO:I0016321 ! smarca5-myo1c physical interaction relationship: participates_in CCO:I0016322 ! smarca5-baz2a physical interaction relationship: participates_in CCO:I0017399 ! hbxap-smarca5-4 physical interaction relationship: participates_in CCO:I0017735 ! baz1b-myo1c-1 physical interaction relationship: participates_in CCO:I0017912 ! hbxap-smarca5 physical interaction relationship: participates_in CCO:I0017913 ! hbxap-smarca5-1 physical interaction relationship: participates_in CCO:I0018218 ! hbxap-smarca5-2 colocalization relationship: participates_in CCO:I0018639 ! smarca5-polr1a colocalization relationship: participates_in CCO:I0019447 ! baz1b-smarca5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070639 ! SMCA5_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0070640 ! SMCA5_HUMAN-Phosphothreonine113 relationship: transforms_into CCO:B0070641 ! SMCA5_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0070642 ! SMCA5_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0070643 ! SMCA5_HUMAN-Phosphoserine755 [Term] id: CCO:B0054539 name: ZN292_HUMAN def: "Zinc finger protein 292" [UniProtKB:O60281] xref: EMBL:BAA25456.1 xref: EMBL:BAB14622.1 xref: EMBL:BAB14654.1 xref: UniProtKB:O60281 xref: UniProtKB:Q9H8G3 xref: UniProtKB:Q9H8J4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020696 ! ZNF292_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072091 ! ZN292_HUMAN-Phosphoserine66 [Term] id: CCO:B0054540 name: ST18_HUMAN def: "Suppression of tumorigenicity protein 18" [UniProtKB:O60284] synonym: "Zinc finger protein 387" EXACT [UniProtKB:O60284] xref: EMBL:AAI17148.1 xref: EMBL:AAI17150.1 xref: EMBL:BAA25461.1 xref: UniProtKB:O60284 xref: UniProtKB:Q17RY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020058 ! ST18_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054541 name: ZN862_HUMAN def: "Zinc finger protein 862" [UniProtKB:O60290] xref: EMBL:AAI13088.1 xref: EMBL:BAA25469.1 xref: UniProtKB:A0AUL8 xref: UniProtKB:O60290 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022825 ! ZNF862_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017284 ! kiaa0543-kiaa1043 physical interaction relationship: participates_in CCO:I0017285 ! kiaa0543-kiaa1218 physical interaction relationship: participates_in CCO:I0018926 ! atn1-kiaa0543 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054542 name: SI1L3_HUMAN def: "Signal-induced proliferation-associated 1-like protein 3" [UniProtKB:O60292] synonym: "SPA-1-like protein 3" EXACT [UniProtKB:O60292] xref: EMBL:AAO12531.1 xref: EMBL:BAA25471.2 xref: UniProtKB:O60292 xref: UniProtKB:Q2TV87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019904 ! SIPA1L3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0070530 ! SI1L3_HUMAN-Phosphoserine1135 relationship: transforms_into CCO:B0070531 ! SI1L3_HUMAN-Phosphotyrosine1265 relationship: transforms_into CCO:B0070532 ! SI1L3_HUMAN-Phosphoserine1364 [Term] id: CCO:B0054543 name: ZN500_HUMAN def: "Zinc finger protein 500" [UniProtKB:O60304] synonym: "Zinc finger protein with KRAB and SCAN domains 18" EXACT [UniProtKB:O60304] xref: EMBL:AAH04125.2 xref: EMBL:AAI21014.1 xref: EMBL:BAA25483.1 xref: UniProtKB:O60304 xref: UniProtKB:Q0VAL2 xref: UniProtKB:Q96CQ8 xref: UniProtKB:Q9BTG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020781 ! ZNF500_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054544 name: AT10A_HUMAN def: "Probable phospholipid-transporting ATPase VA" [UniProtKB:O60312] synonym: "Aminophospholipid translocase VA" EXACT [UniProtKB:O60312] synonym: "ATPVA" EXACT [UniProtKB:O60312] synonym: "EC 3.6.3.1" EXACT [UniProtKB:O60312] xref: EMBL:AAH52251.1 xref: EMBL:AAK33100.1 xref: EMBL:BAA25492.1 xref: EMBL:BAB47392.1 xref: UniProtKB:O60312 xref: UniProtKB:Q969I4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017089 ! ATP10A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0063640 ! AT10A_HUMAN-Phosphoserine646 [Term] id: CCO:B0054545 name: OPA1_HUMAN def: "Dynamin-like 120 kDa protein, mitochondrial precursor" [UniProtKB:O60313] synonym: "Optic atrophy protein 1" EXACT [UniProtKB:O60313] xref: EMBL:AAH75805.1 xref: EMBL:BAA25493.1 xref: UniProtKB:O60313 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019047 ! OPA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000341 ! mitochondrial intermembrane space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000940 ! mitochondrial crista relationship: located_in CCO:C0001005 ! dendrite relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis relationship: transforms_into CCO:B0068969 ! OPA1_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0068970 ! OPA1_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0068971 ! OPA1_HUMAN-Phosphothreonine652 [Term] id: CCO:B0054546 name: ZEB2_HUMAN def: "Zinc finger E-box-binding homeobox 2" [UniProtKB:O60315] synonym: "Smad-interacting protein 1" EXACT [UniProtKB:O60315] synonym: "SMADIP1" EXACT [UniProtKB:O60315] synonym: "Zinc finger homeobox protein 1b" EXACT [UniProtKB:O60315] xref: EMBL:AAI27103.1 xref: EMBL:AAK52081.1 xref: EMBL:BAA25495.2 xref: EMBL:BAA34798.1 xref: EMBL:BAB40819.1 xref: UniProtKB:A0JP09 xref: UniProtKB:O60315 xref: UniProtKB:Q9UED1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020577 ! ZEB2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004131 ! phosphatase regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020217 ! zfhx1b-cops6 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0054547 name: MCM3A_HUMAN def: "80 kDa MCM3-associated protein" [UniProtKB:O60318] synonym: "Protein GANP" EXACT [UniProtKB:O60318] xref: EMBL:AAI04959.1 xref: EMBL:AAI04961.1 xref: EMBL:AAS89300.1 xref: EMBL:BAA25170.1 xref: EMBL:BAA25498.1 xref: EMBL:CAB52687.1 xref: UniProtKB:O60318 xref: UniProtKB:Q2M3C1 xref: UniProtKB:Q9UMT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018591 ! MCM3AP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017289 ! kiaa0911-mcm3ap physical interaction relationship: participates_in CCO:I0020283 ! dc6-mcm3ap physical interaction relationship: participates_in CCO:I0020367 ! mgc:13379-mcm3ap physical interaction relationship: participates_in CCO:I0020389 ! nudt5-mcm3ap physical interaction relationship: participates_in CCO:I0020591 ! mcm3ap-crmp1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0068063 ! MCM3A_HUMAN-Phosphoserine557 [Term] id: CCO:B0054548 name: TBC12_HUMAN def: "TBC1 domain family member 12" [UniProtKB:O60347] xref: EMBL:BAA25534.1 xref: EMBL:CAB43225.2 xref: EMBL:CAH70223.2 xref: EMBL:CAH70583.2 xref: UniProtKB:O60347 xref: UniProtKB:Q5VYA6 xref: UniProtKB:Q8WX26 xref: UniProtKB:Q8WX59 xref: UniProtKB:Q9UG83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020158 ! TBC1D12_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054549 name: FZD6_HUMAN def: "Frizzled-6 precursor" [UniProtKB:O60353] synonym: "Fz-6" EXACT [UniProtKB:O60353] synonym: "hFz6" EXACT [UniProtKB:O60353] xref: EMBL:AAD41637.1 xref: EMBL:AAH60836.2 xref: EMBL:AAL50384.1 xref: EMBL:BAA25686.1 xref: EMBL:BAC05925.1 xref: EMBL:EAW91867.1 xref: UniProtKB:O60353 xref: UniProtKB:Q6P9C3 xref: UniProtKB:Q8WXR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017854 ! FZD6_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000782 ! apicolateral plasma membrane relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054550 name: NUPR1_HUMAN def: "Nuclear protein 1" [UniProtKB:O60356] synonym: "Candidate of metastasis 1" EXACT [UniProtKB:O60356] synonym: "Protein p8" EXACT [UniProtKB:O60356] xref: EMBL:AAC05335.1 xref: EMBL:AAC05336.1 xref: EMBL:AAC19384.1 xref: EMBL:AAC19385.1 xref: EMBL:AAD49221.1 xref: EMBL:AAH02434.1 xref: EMBL:AAP35542.1 xref: UniProtKB:O60356 xref: UniProtKB:O60357 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018892 ! NUPR1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0054551 name: NOBOX_HUMAN def: "Homeobox protein NOBOX" [UniProtKB:O60393] xref: EMBL:AAC12957.1 xref: UniProtKB:A6NCD3 xref: UniProtKB:A8MZN5 xref: UniProtKB:O60393 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018814 ! NOBOX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054552 name: O10H2_HUMAN def: "Olfactory receptor 10H2" [UniProtKB:O60403] synonym: "Olfactory receptor OR19-23" EXACT [UniProtKB:O60403] xref: EMBL:AAC14388.1 xref: EMBL:AAH69085.1 xref: EMBL:AAH69457.1 xref: EMBL:AAI12179.1 xref: EMBL:AAI13648.1 xref: EMBL:AAK95070.1 xref: EMBL:DAA04609.1 xref: UniProtKB:O60403 xref: UniProtKB:Q6IFQ1 xref: UniProtKB:Q96R58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018915 ! OR10H2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054553 name: O10H3_HUMAN def: "Olfactory receptor 10H3" [UniProtKB:O60404] xref: EMBL:AAC14389.1 xref: EMBL:AAI06708.1 xref: EMBL:AAI13845.1 xref: UniProtKB:O60404 xref: UniProtKB:Q2HIZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018916 ! OR10H3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054554 name: O60411_HUMAN def: "BC62940_1" [UniProtKB:O60411] xref: EMBL:AAC15753.1 xref: UniProtKB:O60411 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054555 name: OR7C2_HUMAN def: "Olfactory receptor 7C2" [UniProtKB:O60412] synonym: "Olfactory receptor 19-18" EXACT [UniProtKB:O60412] synonym: "OR19-18" EXACT [UniProtKB:O60412] xref: EMBL:AAC15755.1 xref: EMBL:AAC39626.1 xref: EMBL:AAK95030.1 xref: UniProtKB:O43881 xref: UniProtKB:O60412 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019218 ! OR7C2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054556 name: FADS1_HUMAN def: "Fatty acid desaturase 1" [UniProtKB:O60427] synonym: "D5D" EXACT [UniProtKB:O60427] synonym: "Delta(5) desaturase" EXACT [UniProtKB:O60427] synonym: "Delta(5) fatty acid desaturase" EXACT [UniProtKB:O60427] synonym: "EC 1.14.19.-" EXACT [UniProtKB:O60427] xref: EMBL:AAC23397.1 xref: EMBL:AAF29378.1 xref: EMBL:AAF70457.1 xref: EMBL:AAG23120.1 xref: EMBL:AAH07846.1 xref: EMBL:BAB55103.1 xref: EMBL:BAB55173.1 xref: EMBL:BAC11182.1 xref: EMBL:BAC11229.1 xref: EMBL:BAD96626.1 xref: EMBL:CAC21679.1 xref: EMBL:CAD39138.1 xref: UniProtKB:O60427 xref: UniProtKB:Q53GM5 xref: UniProtKB:Q8N3A6 xref: UniProtKB:Q8NCC7 xref: UniProtKB:Q8NCG0 xref: UniProtKB:Q96I39 xref: UniProtKB:Q96SV3 xref: UniProtKB:Q96T10 xref: UniProtKB:Q9NRP8 xref: UniProtKB:Q9NYX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017756 ! FADS1_human relationship: has_function CCO:F0000047 ! C-5 sterol desaturase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003300 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:B0054557 name: O60428_HUMAN def: "BC269730_4" [UniProtKB:O60428] xref: EMBL:AAC23395.1 xref: UniProtKB:O60428 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054558 name: OR1I1_HUMAN def: "Olfactory receptor 1I1" [UniProtKB:O60431] synonym: "Olfactory receptor 19-20" EXACT [UniProtKB:O60431] synonym: "OR19-20" EXACT [UniProtKB:O60431] xref: EMBL:AAC18915.1 xref: EMBL:AAK95033.1 xref: UniProtKB:O60431 xref: UniProtKB:Q96R92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019068 ! OR1I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054559 name: O60432_HUMAN def: "F02569_2" [UniProtKB:O60432] xref: EMBL:AAC18917.1 xref: UniProtKB:O60432 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054560 name: O60466_HUMAN xref: UniProtKB:O60466 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001462 ! transforming growth factor beta receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054561 name: PLXC1_HUMAN def: "Plexin-C1 precursor" [UniProtKB:O60486] synonym: "CD232 antigen" EXACT [UniProtKB:O60486] synonym: "Virus-encoded semaphorin protein receptor" EXACT [UniProtKB:O60486] xref: EMBL:AAC18823.1 xref: EMBL:BAD92171.1 xref: UniProtKB:O60486 xref: UniProtKB:Q59H25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019451 ! PLXNC1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069427 ! PLXC1_HUMAN-Phosphothreonine1466 [Term] id: CCO:B0054562 name: DOK2_HUMAN def: "Docking protein 2" [UniProtKB:O60496] synonym: "Downstream of tyrosine kinase 2" EXACT [UniProtKB:O60496] synonym: "p56(dok-2)" EXACT [UniProtKB:O60496] xref: EMBL:AAC13265.1 xref: EMBL:AAH32623.1 xref: UniProtKB:O60496 xref: UniProtKB:Q8N5A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017602 ! DOK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0064845 ! DOK2_HUMAN-Phosphotyrosine271 relationship: transforms_into CCO:B0064846 ! DOK2_HUMAN-Phosphotyrosine299 relationship: transforms_into CCO:B0064847 ! DOK2_HUMAN-Phosphotyrosine345 [Term] id: CCO:B0054563 name: ADCY9_HUMAN def: "Adenylate cyclase type 9" [UniProtKB:O60503] synonym: "Adenylate cyclase type IX" EXACT [UniProtKB:O60503] synonym: "Adenylyl cyclase 9" EXACT [UniProtKB:O60503] synonym: "ATP pyrophosphate-lyase 9" EXACT [UniProtKB:O60503] synonym: "EC 4.6.1.1" EXACT [UniProtKB:O60503] xref: EMBL:AAC24201.1 xref: EMBL:AAK29464.1 xref: EMBL:AAY21237.1 xref: EMBL:AAY27880.1 xref: EMBL:BAA25446.3 xref: EMBL:CAB65084.1 xref: UniProtKB:O60273 xref: UniProtKB:O60503 xref: UniProtKB:Q4ZHT9 xref: UniProtKB:Q4ZIR5 xref: UniProtKB:Q9BWT4 xref: UniProtKB:Q9UGP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016914 ! ADCY9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0065407 ! ADCY9_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0065408 ! ADCY9_HUMAN-Phosphothreonine608 relationship: transforms_into CCO:B0065409 ! ADCY9_HUMAN-Phosphoserine610 [Term] id: CCO:B0054564 name: VINEX_HUMAN def: "Vinexin" [UniProtKB:O60504] synonym: "SCAM-1" EXACT [UniProtKB:O60504] synonym: "SH3-containing adapter molecule 1" EXACT [UniProtKB:O60504] synonym: "Sorbin and SH3 domain-containing protein 3" EXACT [UniProtKB:O60504] xref: EMBL:AAC09244.1 xref: EMBL:AAD32304.1 xref: EMBL:AAH91514.1 xref: UniProtKB:O60504 xref: UniProtKB:Q5BJE4 xref: UniProtKB:Q9UQE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020449 ! SORBS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis relationship: participates_in CCO:P0003108 ! positive regulation of stress fiber formation relationship: transforms_into CCO:B0071802 ! VINEX_HUMAN-Phosphoserine348 relationship: transforms_into CCO:B0071803 ! VINEX_HUMAN-Phosphothreonine529 relationship: transforms_into CCO:B0071804 ! VINEX_HUMAN-Phosphoserine530 relationship: transforms_into CCO:B0071805 ! VINEX_HUMAN-Phosphoserine545 relationship: transforms_into CCO:B0071806 ! VINEX_HUMAN-Phosphoserine551 relationship: transforms_into CCO:B0071807 ! VINEX_HUMAN-Phosphoserine563 [Term] id: CCO:B0054565 name: 4EBP3_HUMAN def: "Eukaryotic translation initiation factor 4E-binding protein 3" [UniProtKB:O60516] synonym: "4E-BP3" EXACT [UniProtKB:O60516] synonym: "eIF4E-binding protein 3" EXACT [UniProtKB:O60516] xref: EMBL:AAC39761.1 xref: EMBL:AAH10881.1 xref: EMBL:AAH69293.1 xref: EMBL:AAH73751.1 xref: UniProtKB:O60516 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016849 ! EIF4EBP3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001770 ! eukaryotic initiation factor 4E binding relationship: has_function CCO:F0004416 ! translation repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: participates_in CCO:I0015295 ! eif4ebp3-eif4el3 physical interaction relationship: participates_in CCO:I0016156 ! eif4e-4ebp3-1 direct interaction relationship: participates_in CCO:I0019454 ! eif4e-4ebp3-2 direct interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002630 ! negative regulation of translational initiation [Term] id: CCO:B0054566 name: CIDEA_HUMAN def: "Cell death activator CIDE-A" [UniProtKB:O60543] synonym: "Cell death-inducing DFFA-like effector A" EXACT [UniProtKB:O60543] xref: EMBL:AAC34987.1 xref: UniProtKB:O60543 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017362 ! CIDEA_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0001273 ! negative regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0054567 name: IF4E2_HUMAN def: "Eukaryotic translation initiation factor 4E type 2" [UniProtKB:O60573] synonym: "eIF-4E type 2" EXACT [UniProtKB:O60573] synonym: "eIF4E type 2" EXACT [UniProtKB:O60573] synonym: "eIF4E-like protein 4E-LP" EXACT [UniProtKB:O60573] synonym: "Eukaryotic translation initiation factor 4E homologous protein" EXACT [UniProtKB:O60573] synonym: "Eukaryotic translation initiation factor 4E-like 3" EXACT [UniProtKB:O60573] synonym: "mRNA cap-binding protein 4EHP" EXACT [UniProtKB:O60573] synonym: "mRNA cap-binding protein type 3" EXACT [UniProtKB:O60573] xref: EMBL:AAC18565.1 xref: EMBL:AAC19374.1 xref: EMBL:AAC39871.1 xref: EMBL:AAH05392.1 xref: EMBL:AAH05874.1 xref: EMBL:AAH21226.1 xref: EMBL:AAH21690.1 xref: UniProtKB:O60573 xref: UniProtKB:O75349 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018227 ! EIF4E2_human relationship: has_function CCO:F0000071 ! RNA cap binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015250 ! eif4el3-eif4enif1 physical interaction relationship: participates_in CCO:I0015295 ! eif4ebp3-eif4el3 physical interaction relationship: participates_in CCO:I0015412 ! eif4el3-krt20 physical interaction relationship: participates_in CCO:I0015567 ! eif4el3-krtap4_12 physical interaction relationship: participates_in CCO:I0017668 ! eif4el3-eif4ebp1-1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0054568 name: O60587_HUMAN def: "Alpha1-fetoprotein transcription factor short variant" [UniProtKB:O60587] xref: EMBL:AAD03248.1 xref: UniProtKB:O60587 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021070 ! FTF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054569 name: TLR5_HUMAN def: "Toll-like receptor 5 precursor" [UniProtKB:O60602] synonym: "Toll/interleukin-1 receptor-like protein 3" EXACT [UniProtKB:O60602] xref: EMBL:AAC34136.1 xref: EMBL:AAC34376.1 xref: EMBL:AAI09119.1 xref: EMBL:BAB43955.1 xref: EMBL:CAM28378.1 xref: UniProtKB:B1AZ05 xref: UniProtKB:O15456 xref: UniProtKB:O60602 xref: UniProtKB:Q32MI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020281 ! TLR5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054570 name: GFRA3_HUMAN def: "GDNF family receptor alpha-3 precursor" [UniProtKB:O60609] synonym: "GFR-alpha-3" EXACT [UniProtKB:O60609] xref: EMBL:AAC24355.1 xref: EMBL:AAH37951.1 xref: EMBL:AAQ89356.1 xref: EMBL:AAQ89396.1 xref: UniProtKB:O60609 xref: UniProtKB:Q6UW20 xref: UniProtKB:Q8IUZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017918 ! GFRA3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054571 name: PDE8A_HUMAN def: "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A" [UniProtKB:O60658] synonym: "EC 3.1.4.17" EXACT [UniProtKB:O60658] xref: EMBL:AAC39763.1 xref: EMBL:AAH75822.1 xref: EMBL:AAL18610.1 xref: EMBL:AAL18611.1 xref: EMBL:AAL18612.1 xref: EMBL:AAL18613.1 xref: EMBL:AAL18614.1 xref: EMBL:CAB52020.1 xref: EMBL:CAB52432.1 xref: UniProtKB:O60658 xref: UniProtKB:Q969I1 xref: UniProtKB:Q96PC9 xref: UniProtKB:Q96PD0 xref: UniProtKB:Q96PD1 xref: UniProtKB:Q9UMB7 xref: UniProtKB:Q9UMC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019346 ! PDE8A_human relationship: has_function CCO:F0000030 ! two-component response regulator activity relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054572 name: LMX1B_HUMAN def: "LIM homeobox transcription factor 1-beta" [UniProtKB:O60663] synonym: "LIM/homeobox protein 1.2" EXACT [UniProtKB:O60663] synonym: "LIM/homeobox protein LMX1B" EXACT [UniProtKB:O60663] synonym: "LMX-1.2" EXACT [UniProtKB:O60663] xref: EMBL:AAC27294.1 xref: EMBL:AAC39738.1 xref: EMBL:AAH69601.1 xref: EMBL:AAI12121.1 xref: EMBL:AAI13492.1 xref: EMBL:CAH70294.1 xref: EMBL:CAH70295.1 xref: EMBL:CAI40917.1 xref: EMBL:CAI40918.1 xref: EMBL:EAW87642.1 xref: UniProtKB:O60663 xref: UniProtKB:O75463 xref: UniProtKB:Q5JU95 xref: UniProtKB:Q6ISC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018512 ! LMX1B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054573 name: FAIM3_HUMAN def: "Fas apoptotic inhibitory molecule 3 precursor" [UniProtKB:O60667] synonym: "Regulator of Fas-induced apoptosis Toso" EXACT [UniProtKB:O60667] xref: EMBL:AAC18830.1 xref: EMBL:AAH06401.1 xref: EMBL:AAP35443.1 xref: UniProtKB:O60667 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017760 ! FAIM3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054574 name: DPOLZ_HUMAN def: "DNA polymerase zeta catalytic subunit" [UniProtKB:O60673] synonym: "EC 2.7.7.7" EXACT [UniProtKB:O60673] synonym: "hREV3" EXACT [UniProtKB:O60673] xref: EMBL:AAB88486.1 xref: EMBL:AAC24009.1 xref: EMBL:AAC24357.1 xref: EMBL:AAC28460.1 xref: EMBL:AAD40184.1 xref: EMBL:AAG09402.1 xref: EMBL:AAG09403.1 xref: EMBL:AAT74627.1 xref: EMBL:CAI19192.1 xref: EMBL:CAI20509.1 xref: EMBL:CAI20998.1 xref: UniProtKB:O43214 xref: UniProtKB:O60673 xref: UniProtKB:Q5TC33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017612 ! REV3L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: transforms_into CCO:B0064858 ! DPOLZ_HUMAN-Phosphothreonine582 relationship: transforms_into CCO:B0064859 ! DPOLZ_HUMAN-Phosphoserine583 relationship: transforms_into CCO:B0064860 ! DPOLZ_HUMAN-Phosphothreonine2298 relationship: transforms_into CCO:B0064861 ! DPOLZ_HUMAN-Phosphoserine2522 [Term] id: CCO:B0054575 name: MUSC_HUMAN def: "Musculin" [UniProtKB:O60682] synonym: "ABF-1" EXACT [UniProtKB:O60682] synonym: "Activated B-cell factor 1" EXACT [UniProtKB:O60682] xref: EMBL:AAC15071.1 xref: EMBL:AAC69870.1 xref: EMBL:AAH06313.1 xref: EMBL:AAH67827.1 xref: UniProtKB:O60682 xref: UniProtKB:O75946 xref: UniProtKB:Q9BRE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018684 ! MSC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014966 ! ewsr1-msc physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054576 name: GALR3_HUMAN def: "Galanin receptor type 3" [UniProtKB:O60755] synonym: "GAL3-R" EXACT [UniProtKB:O60755] synonym: "GALR3" EXACT [UniProtKB:O60755] xref: EMBL:AAC18860.1 xref: EMBL:AAC35944.1 xref: EMBL:AAD47348.2 xref: EMBL:BAC06149.1 xref: EMBL:CAB42831.1 xref: UniProtKB:O60755 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017863 ! GALR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001307 ! galanin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054577 name: CYTIP_HUMAN def: "Cytohesin-interacting protein" [UniProtKB:O60759] synonym: "CASP" EXACT [UniProtKB:O60759] synonym: "CYBR" EXACT [UniProtKB:O60759] synonym: "Cytohesin binder and regulator" EXACT [UniProtKB:O60759] synonym: "Cytohesin-associated scaffolding protein" EXACT [UniProtKB:O60759] synonym: "Cytohesin-binding protein HE" EXACT [UniProtKB:O60759] synonym: "Pleckstrin homology Sec7 and coiled-coil domains-binding protein" EXACT [UniProtKB:O60759] xref: EMBL:AAA16575.1 xref: EMBL:AAC19129.1 xref: EMBL:AAH36449.1 xref: EMBL:AAY14898.1 xref: UniProtKB:O60759 xref: UniProtKB:Q15630 xref: UniProtKB:Q8NE32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022169 ! CYTIP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000489 ! cell cortex relationship: participates_in CCO:I0015997 ! pscdbp-pscd1-1 physical interaction relationship: participates_in CCO:I0015998 ! pscd1-pscdbp-1 physical interaction relationship: participates_in CCO:P0001245 ! regulation of cell adhesion [Term] id: CCO:B0054578 name: PTGD2_HUMAN def: "Glutathione-requiring prostaglandin D synthase" [UniProtKB:O60760] synonym: "EC 5.3.99.2" EXACT [UniProtKB:O60760] synonym: "Glutathione-dependent PGD synthetase" EXACT [UniProtKB:O60760] synonym: "H-PGDS" EXACT [UniProtKB:O60760] synonym: "Hematopoietic prostaglandin D synthase" EXACT [UniProtKB:O60760] synonym: "Prostaglandin-H2 D-isomerase" EXACT [UniProtKB:O60760] xref: EMBL:AAH20734.1 xref: EMBL:BAA25545.1 xref: EMBL:BAA96854.1 xref: UniProtKB:O60760 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019539 ! PTGDS2_human relationship: has_function CCO:F0001040 ! prostaglandin-D synthase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054579 name: Z354A_HUMAN def: "Zinc finger protein 354A" [UniProtKB:O60765] synonym: "Transcription factor 17" EXACT [UniProtKB:O60765] synonym: "Zinc finger protein eZNF" EXACT [UniProtKB:O60765] xref: EMBL:AAD05335.1 xref: EMBL:BAA25182.1 xref: UniProtKB:O60765 xref: UniProtKB:Q9UNJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020523 ! ZNF354A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054580 name: TBX19_HUMAN def: "T-box transcription factor TBX19" [UniProtKB:O60806] synonym: "T-box factor, pituitary" EXACT [UniProtKB:O60806] synonym: "T-box protein 19" EXACT [UniProtKB:O60806] xref: EMBL:AAH93664.1 xref: EMBL:AAH93666.1 xref: EMBL:CAB37936.1 xref: EMBL:CAI22640.1 xref: UniProtKB:O60806 xref: UniProtKB:Q52M53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020193 ! TBX19_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054581 name: IF2P_HUMAN def: "Eukaryotic translation initiation factor 5B" [UniProtKB:O60841] synonym: "eIF-5B" EXACT [UniProtKB:O60841] synonym: "Translation initiation factor IF-2" EXACT [UniProtKB:O60841] xref: EMBL:AAD16006.1 xref: EMBL:BAA34461.2 xref: EMBL:CAA07018.1 xref: EMBL:CAB44357.1 xref: EMBL:CAB63717.1 xref: UniProtKB:O60841 xref: UniProtKB:O95805 xref: UniProtKB:Q9UF81 xref: UniProtKB:Q9UMN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018224 ! EIF5B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017975 ! eif1a-eif5b-2 direct interaction relationship: participates_in CCO:I0018055 ! eif1a-eif5b-1 direct interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0067011 ! IF2P_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0067012 ! IF2P_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0067013 ! IF2P_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0067014 ! IF2P_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0067015 ! IF2P_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0067016 ! IF2P_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0067017 ! IF2P_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0067018 ! IF2P_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0067019 ! IF2P_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0067020 ! IF2P_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0067021 ! IF2P_HUMAN-Phosphoserine1168 [Term] id: CCO:B0054582 name: EDF1_HUMAN def: "Endothelial differentiation-related factor 1" [UniProtKB:O60869] synonym: "EDF-1" EXACT [UniProtKB:O60869] synonym: "MBF1" EXACT [UniProtKB:O60869] synonym: "Multiprotein-bridging factor 1" EXACT [UniProtKB:O60869] xref: EMBL:AAH15500.1 xref: EMBL:AAP88865.1 xref: EMBL:BAA88073.1 xref: EMBL:BAA88074.1 xref: EMBL:CAA06446.1 xref: EMBL:CAG46712.1 xref: EMBL:CAI12697.1 xref: EMBL:CAI12698.1 xref: EMBL:CAI12699.1 xref: UniProtKB:O60869 xref: UniProtKB:Q5T5T2 xref: UniProtKB:Q9UIM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017658 ! EDF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015966 ! edf1-nr5a1-8 colocalization relationship: participates_in CCO:I0017384 ! edf1-pparg-4 physical interaction relationship: participates_in CCO:I0017516 ! edf1-pparg-1 physical interaction relationship: participates_in CCO:I0017517 ! edf1-nr1h3-4 physical interaction relationship: participates_in CCO:I0018207 ! edf1-pparg-3 physical interaction relationship: participates_in CCO:I0018342 ! edf1-nr1h3-3 physical interaction relationship: participates_in CCO:I0018343 ! tbp-edf1-1 physical interaction relationship: participates_in CCO:I0018848 ! edf1-nr5a2-1 physical interaction relationship: participates_in CCO:I0018849 ! edf1-rxra-1 physical interaction relationship: participates_in CCO:I0018850 ! edf1-nr5a2-2 physical interaction relationship: participates_in CCO:I0018851 ! edf1-nr1h3-2 physical interaction relationship: participates_in CCO:I0018852 ! edf1-pparg-2 physical interaction relationship: participates_in CCO:I0019284 ! edf1-nr1h3-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054583 name: KIN17_HUMAN def: "DNA/RNA-binding protein KIN17" [UniProtKB:O60870] synonym: "Binding to curved DNA" EXACT [UniProtKB:O60870] synonym: "KIN, antigenic determinant of recA protein homolog" EXACT [UniProtKB:O60870] xref: EMBL:AAH17309.1 xref: EMBL:CAA06462.1 xref: EMBL:CAI12959.1 xref: UniProtKB:O60870 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022353 ! KIN_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0054584 name: DIAP2_HUMAN def: "Protein diaphanous homolog 2" [UniProtKB:O60879] synonym: "Diaphanous-related formin-2" EXACT [UniProtKB:O60879] synonym: "DRF2" EXACT [UniProtKB:O60879] xref: EMBL:CAA75869.1 xref: EMBL:CAA75870.1 xref: EMBL:CAB39108.2 xref: EMBL:CAD13477.2 xref: EMBL:CAH71113.1 xref: EMBL:CAH71114.1 xref: EMBL:CAH71361.1 xref: EMBL:CAI39841.1 xref: EMBL:CAI39842.1 xref: EMBL:CAI39928.1 xref: EMBL:CAI40544.1 xref: EMBL:CAI40545.1 xref: EMBL:CAI40915.1 xref: EMBL:CAI40916.1 xref: EMBL:CAI42257.1 xref: EMBL:CAI42258.1 xref: EMBL:CAI42515.1 xref: UniProtKB:A6NG19 xref: UniProtKB:O60878 xref: UniProtKB:O60879 xref: UniProtKB:Q8WX06 xref: UniProtKB:Q8WX48 xref: UniProtKB:Q9UJL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017577 ! DIAPH2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0003531 ! Rho GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: participates_in CCO:P0000453 ! cytokinesis relationship: transforms_into CCO:B0064764 ! DIAP2_HUMAN-Phosphotyrosine632 [Term] id: CCO:B0054585 name: ETBR2_HUMAN def: "Endothelin B receptor-like protein 2 precursor" [UniProtKB:O60883] synonym: "ETBR-LP-2" EXACT [UniProtKB:O60883] synonym: "G-protein coupled receptor 37-like 1" EXACT [UniProtKB:O60883] xref: EMBL:AAH50334.1 xref: EMBL:BAD96359.1 xref: EMBL:CAA76153.1 xref: EMBL:CAI13106.1 xref: UniProtKB:O60883 xref: UniProtKB:Q5SXP7 xref: UniProtKB:Q86VP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017733 ! GPR37L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0065165 ! ETBR2_HUMAN-Phosphoserine471 [Term] id: CCO:B0054586 name: OPHN1_HUMAN def: "Oligophrenin-1" [UniProtKB:O60890] xref: EMBL:BAC81125.1 xref: EMBL:CAA04579.1 xref: EMBL:CAB96181.1 xref: EMBL:CAD18899.2 xref: EMBL:CAI40982.1 xref: EMBL:CAI41508.1 xref: EMBL:CAI42695.1 xref: UniProtKB:O60890 xref: UniProtKB:Q5JQ81 xref: UniProtKB:Q8WX47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019048 ! OPHN1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054587 name: RAMP1_HUMAN def: "Receptor activity-modifying protein 1 precursor" [UniProtKB:O60894] synonym: "Calcitonin-receptor-like receptor activity-modifying protein 1" EXACT [UniProtKB:O60894] synonym: "CRLR activity-modifying protein 1" EXACT [UniProtKB:O60894] xref: EMBL:AAH00548.1 xref: EMBL:AAP23298.1 xref: EMBL:CAA04472.1 xref: UniProtKB:O60894 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019620 ! RAMP1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018093 ! calcrl-ramp1-1 colocalization relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054588 name: SHOX2_HUMAN def: "Short stature homeobox protein 2" [UniProtKB:O60902] synonym: "Homeobox protein Og12X" EXACT [UniProtKB:O60902] synonym: "Paired-related homeobox protein SHOT" EXACT [UniProtKB:O60902] xref: EMBL:AAC39662.1 xref: EMBL:AAC39663.1 xref: EMBL:AAH08829.1 xref: EMBL:CAA05341.1 xref: EMBL:CAA05342.1 xref: UniProtKB:O60465 xref: UniProtKB:O60467 xref: UniProtKB:O60902 xref: UniProtKB:O60903 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019899 ! SHOX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054589 name: NSMA_HUMAN def: "Sphingomyelin phosphodiesterase 2" [UniProtKB:O60906] synonym: "EC 3.1.4.12" EXACT [UniProtKB:O60906] synonym: "Lyso-PAF-PLC" EXACT [UniProtKB:O60906] synonym: "Lyso-platelet-activating factor-phospholipase C" EXACT [UniProtKB:O60906] synonym: "N-SMase" EXACT [UniProtKB:O60906] synonym: "Neutral sphingomyelinase" EXACT [UniProtKB:O60906] synonym: "nSMase" EXACT [UniProtKB:O60906] xref: EMBL:AAH00038.1 xref: EMBL:CAA10995.1 xref: UniProtKB:O60906 xref: UniProtKB:Q9BWR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018878 ! SMPD2_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001127 ! sphingomyelin phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0054590 name: TBL1X_HUMAN def: "F-box-like/WD repeat-containing protein TBL1X" [UniProtKB:O60907] synonym: "SMAP55" EXACT [UniProtKB:O60907] synonym: "Transducin beta-like 1X protein" EXACT [UniProtKB:O60907] synonym: "Transducin-beta-like 1, X-linked" EXACT [UniProtKB:O60907] xref: EMBL:AAH32708.1 xref: EMBL:AAH52304.1 xref: EMBL:CAA73319.1 xref: UniProtKB:O60907 xref: UniProtKB:Q86UY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020188 ! TBL1X_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054591 name: NOL3_HUMAN def: "Nucleolar protein 3" [UniProtKB:O60936] synonym: "Apoptosis repressor with CARD" EXACT [UniProtKB:O60936] synonym: "Muscle-enriched cytoplasmic protein" EXACT [UniProtKB:O60936] synonym: "Myp" EXACT [UniProtKB:O60936] synonym: "Nop30" EXACT [UniProtKB:O60936] synonym: "Nucleolar protein of 30 kDa" EXACT [UniProtKB:O60936] xref: EMBL:AAC18590.1 xref: EMBL:AAC18591.1 xref: EMBL:AAC18593.1 xref: EMBL:AAC18594.1 xref: EMBL:AAC34993.1 xref: EMBL:AAH12798.1 xref: UniProtKB:O60936 xref: UniProtKB:O60937 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018817 ! NOL3_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0014990 ! nol3-nol3 physical interaction relationship: participates_in CCO:I0015166 ! nol3-ptpns1 physical interaction relationship: participates_in CCO:I0015395 ! nol3-vasp physical interaction relationship: participates_in CCO:I0015471 ! nif3l1-nol3 physical interaction relationship: participates_in CCO:I0015793 ! etnk2-nol3 physical interaction relationship: participates_in CCO:I0019432 ! nol3-nol3-1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0054592 name: LIRA1_HUMAN def: "Leukocyte immunoglobulin-like receptor subfamily A member 1 precursor" [UniProtKB:O75019] synonym: "CD85 antigen-like family member I" EXACT [UniProtKB:O75019] synonym: "CD85i antigen" EXACT [UniProtKB:O75019] synonym: "Leukocyte immunoglobulin-like receptor 6" EXACT [UniProtKB:O75019] synonym: "LIR-6" EXACT [UniProtKB:O75019] xref: EMBL:AAB87663.1 xref: EMBL:AAB87664.1 xref: EMBL:AAI01515.1 xref: UniProtKB:O75018 xref: UniProtKB:O75019 xref: UniProtKB:Q3MJA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018495 ! LILRA1_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054593 name: LIRB3_HUMAN def: "Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor" [UniProtKB:O75022] synonym: "CD85 antigen-like family member A" EXACT [UniProtKB:O75022] synonym: "CD85a antigen" EXACT [UniProtKB:O75022] synonym: "ILT-5" EXACT [UniProtKB:O75022] synonym: "Immunoglobulin-like transcript 5" EXACT [UniProtKB:O75022] synonym: "Leukocyte immunoglobulin-like receptor 3" EXACT [UniProtKB:O75022] synonym: "LIR-3" EXACT [UniProtKB:O75022] synonym: "Monocyte inhibitory receptor HL9" EXACT [UniProtKB:O75022] xref: EMBL:AAB68668.1 xref: EMBL:AAB87667.1 xref: EMBL:AAP30716.1 xref: UniProtKB:O15471 xref: UniProtKB:O75022 xref: UniProtKB:Q86U49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018499 ! LILRB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0067681 ! LIRB3_HUMAN-Phosphothreonine480 [Term] id: CCO:B0054594 name: LIRB5_HUMAN def: "Leukocyte immunoglobulin-like receptor subfamily B member 5 precursor" [UniProtKB:O75023] synonym: "CD85 antigen-like family member C" EXACT [UniProtKB:O75023] synonym: "CD85c antigen" EXACT [UniProtKB:O75023] synonym: "Leukocyte immunoglobulin-like receptor 8" EXACT [UniProtKB:O75023] synonym: "LIR-8" EXACT [UniProtKB:O75023] xref: EMBL:AAB87668.1 xref: EMBL:AAH25704.1 xref: EMBL:BAB71361.1 xref: UniProtKB:O75023 xref: UniProtKB:Q8N760 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018501 ! LILRB5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054595 name: MITF_HUMAN def: "Microphthalmia-associated transcription factor" [UniProtKB:O75030] xref: EMBL:AAC39639.1 xref: EMBL:AAH26961.1 xref: EMBL:AAH65243.1 xref: EMBL:BAA32288.1 xref: EMBL:BAA95206.1 xref: EMBL:BAA95207.1 xref: EMBL:BAA95208.1 xref: EMBL:BAA95209.1 xref: EMBL:CAA82775.1 xref: EMBL:CAB53672.1 xref: UniProtKB:O75030 xref: UniProtKB:Q14841 xref: UniProtKB:Q9P2V0 xref: UniProtKB:Q9P2V1 xref: UniProtKB:Q9P2V2 xref: UniProtKB:Q9P2Y8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018627 ! MITF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068202 ! MITF_HUMAN-Phosphothreonine54 relationship: transforms_into CCO:B0068203 ! MITF_HUMAN-Phosphoserine405 relationship: transforms_into CCO:B0068204 ! MITF_HUMAN-Phosphoserine414 [Term] id: CCO:B0054596 name: PLCH2_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2" [UniProtKB:O75038] synonym: "EC 3.1.4.11" EXACT [UniProtKB:O75038] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:O75038] synonym: "Phosphoinositide phospholipase C-like 4" EXACT [UniProtKB:O75038] synonym: "Phospholipase C-eta-2" EXACT [UniProtKB:O75038] synonym: "Phospholipase C-like protein 4" EXACT [UniProtKB:O75038] synonym: "PLC-eta2" EXACT [UniProtKB:O75038] synonym: "PLC-L4" EXACT [UniProtKB:O75038] xref: EMBL:AAH19679.1 xref: EMBL:AAH43358.1 xref: EMBL:AAH50037.1 xref: EMBL:AAI28208.1 xref: EMBL:ABA12209.1 xref: EMBL:BAA32295.3 xref: EMBL:BAB84975.1 xref: EMBL:BAC56932.1 xref: UniProtKB:A2VCM3 xref: UniProtKB:O75038 xref: UniProtKB:Q3LUA8 xref: UniProtKB:Q86XJ2 xref: UniProtKB:Q86XU1 xref: UniProtKB:Q86YU7 xref: UniProtKB:Q8TEH5 xref: UniProtKB:Q8WUS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019436 ! PLCH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069398 ! PLCH2_HUMAN-Phosphoserine595 relationship: transforms_into CCO:B0069399 ! PLCH2_HUMAN-Phosphoserine605 [Term] id: CCO:B0054597 name: O75039_HUMAN xref: UniProtKB:O75039 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054598 name: FNBP2_HUMAN def: "SLIT-ROBO Rho GTPase-activating protein 2" [UniProtKB:O75044] synonym: "Formin-binding protein 2" EXACT [UniProtKB:O75044] synonym: "srGAP2" EXACT [UniProtKB:O75044] xref: EMBL:BAA32301.1 xref: UniProtKB:O75044 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017816 ! SRGAP2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0017462 ! disc1-srgap2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066233 ! FNBP2_HUMAN-Phosphoserine799 [Term] id: CCO:B0054599 name: PLXA2_HUMAN def: "Plexin-A2 precursor" [UniProtKB:O75051] synonym: "Semaphorin receptor OCT" EXACT [UniProtKB:O75051] xref: EMBL:AAH06193.2 xref: EMBL:AAH09343.2 xref: EMBL:AAI32677.2 xref: EMBL:AAI36531.1 xref: EMBL:AAQ88860.1 xref: EMBL:BAA32308.1 xref: EMBL:CAB57275.1 xref: EMBL:CAI39808.1 xref: EMBL:CAI40198.1 xref: UniProtKB:A2RTX9 xref: UniProtKB:B2RMX7 xref: UniProtKB:O75051 xref: UniProtKB:Q6UX61 xref: UniProtKB:Q96GN9 xref: UniProtKB:Q9BRL1 xref: UniProtKB:Q9UIW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019447 ! PLXNA2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017282 ! kiaa0463-kiaa1199 physical interaction relationship: participates_in CCO:I0017283 ! kiaa0463-pdcd6ip physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069422 ! PLXA2_HUMAN-Phosphoserine1645 relationship: transforms_into CCO:B0069423 ! PLXA2_HUMAN-Phosphoserine1648 [Term] id: CCO:B0054600 name: O75062_HUMAN xref: UniProtKB:O75062 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054601 name: MTG16_HUMAN def: "Protein CBFA2T3" [UniProtKB:O75081] synonym: "hMTG16" EXACT [UniProtKB:O75081] synonym: "MTG8-related protein 2" EXACT [UniProtKB:O75081] synonym: "Myeloid translocation gene on chromosome 16 protein" EXACT [UniProtKB:O75081] synonym: "Zinc finger MYND domain-containing protein 4" EXACT [UniProtKB:O75081] xref: EMBL:AAC64698.1 xref: EMBL:AAC64701.1 xref: EMBL:AAC64702.1 xref: EMBL:AAH47019.1 xref: EMBL:AAH62624.1 xref: EMBL:BAA29061.1 xref: EMBL:BAA29062.1 xref: EMBL:BAA31276.1 xref: EMBL:BAA31277.1 xref: UniProtKB:O60615 xref: UniProtKB:O60616 xref: UniProtKB:O60617 xref: UniProtKB:O75081 xref: UniProtKB:O75082 xref: UniProtKB:O75107 xref: UniProtKB:O75108 xref: UniProtKB:Q0P5Z6 xref: UniProtKB:Q6P5W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018677 ! CBFA2T3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054602 name: ROCK2_HUMAN def: "Rho-associated protein kinase 2" [UniProtKB:O75116] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O75116] synonym: "p164 ROCK-2" EXACT [UniProtKB:O75116] synonym: "Rho kinase 2" EXACT [UniProtKB:O75116] synonym: "Rho-associated, coiled-coil-containing protein kinase 2" EXACT [UniProtKB:O75116] xref: EMBL:BAA31594.2 xref: EMBL:BAA75636.1 xref: UniProtKB:O75116 xref: UniProtKB:Q9UQN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019766 ! ROCK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0070133 ! ROCK2_HUMAN-Phosphothreonine1078 relationship: transforms_into CCO:B0070134 ! ROCK2_HUMAN-Phosphoserine1134 relationship: transforms_into CCO:B0070135 ! ROCK2_HUMAN-Phosphoserine1137 relationship: transforms_into CCO:B0070136 ! ROCK2_HUMAN-Phosphoserine1362 relationship: transforms_into CCO:B0070137 ! ROCK2_HUMAN-Phosphoserine1374 [Term] id: CCO:B0054603 name: ZN623_HUMAN def: "Zinc finger protein 623" [UniProtKB:O75123] xref: EMBL:AAH67516.1 xref: EMBL:AAH67517.1 xref: EMBL:AAH67518.1 xref: EMBL:AAH75056.1 xref: EMBL:AAH75057.1 xref: EMBL:BAA31603.2 xref: UniProtKB:O75123 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020862 ! ZNF623_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054604 name: DEPD5_HUMAN def: "DEP domain-containing protein 5" [UniProtKB:O75140] xref: EMBL:AAD08635.1 xref: EMBL:AAH57797.1 xref: EMBL:BAA31620.2 xref: EMBL:CAE45904.1 xref: EMBL:CAG27889.1 xref: EMBL:CAG27890.1 xref: EMBL:CAG28924.1 xref: EMBL:CAH18159.1 xref: EMBL:CAI17972.1 xref: EMBL:CAI17973.1 xref: EMBL:CAI17974.1 xref: EMBL:CAI17975.1 xref: EMBL:CAI17976.1 xref: EMBL:CAI18776.1 xref: EMBL:CAI18777.1 xref: EMBL:CAI18778.1 xref: EMBL:CAI18779.1 xref: EMBL:CAI19696.1 xref: EMBL:CAI19697.1 xref: EMBL:CAI19698.1 xref: EMBL:CAI19699.1 xref: UniProtKB:O75140 xref: UniProtKB:Q5K3V5 xref: UniProtKB:Q5THY9 xref: UniProtKB:Q5THZ0 xref: UniProtKB:Q5THZ1 xref: UniProtKB:Q5THZ3 xref: UniProtKB:Q68DR1 xref: UniProtKB:Q6MZX3 xref: UniProtKB:Q6PEZ1 xref: UniProtKB:Q9UGV8 xref: UniProtKB:Q9UH13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017556 ! DEPDC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054605 name: ICOSL_HUMAN def: "ICOS ligand precursor" [UniProtKB:O75144] synonym: "B7 homolog 2" EXACT [UniProtKB:O75144] synonym: "B7-H2" EXACT [UniProtKB:O75144] synonym: "B7-like protein Gl50" EXACT [UniProtKB:O75144] synonym: "B7-related protein 1" EXACT [UniProtKB:O75144] synonym: "B7RP-1" EXACT [UniProtKB:O75144] synonym: "CD275 antigen" EXACT [UniProtKB:O75144] xref: EMBL:AAF34739.1 xref: EMBL:AAG01176.1 xref: EMBL:AAH64637.1 xref: EMBL:AAK16241.1 xref: EMBL:BAA31628.1 xref: EMBL:CAC36465.1 xref: UniProtKB:O75144 xref: UniProtKB:Q9HD18 xref: UniProtKB:Q9NRQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018215 ! ICOSLG_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002043 ! positive regulation of activated T cell proliferation [Term] id: CCO:B0054606 name: CAND2_HUMAN def: "Cullin-associated NEDD8-dissociated protein 2" [UniProtKB:O75155] synonym: "Cullin-associated and neddylation-dissociated protein 2" EXACT [UniProtKB:O75155] synonym: "p120 CAND2" EXACT [UniProtKB:O75155] xref: EMBL:BAA31642.1 xref: UniProtKB:O75155 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017222 ! CAND2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003518 ! TATA-binding protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054607 name: T22D2_HUMAN def: "TSC22 domain family protein 2" [UniProtKB:O75157] synonym: "TSC22-related-inducible leucine zipper protein 4" EXACT [UniProtKB:O75157] xref: EMBL:AAG41223.1 xref: EMBL:AAG41224.1 xref: EMBL:AAG41225.1 xref: EMBL:AAH44643.1 xref: EMBL:BAA31644.2 xref: UniProtKB:O75157 xref: UniProtKB:Q6PI50 xref: UniProtKB:Q9H2Z6 xref: UniProtKB:Q9H2Z7 xref: UniProtKB:Q9H2Z8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020088 ! TSC22D2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054608 name: SOCS5_HUMAN def: "Suppressor of cytokine signaling 5" [UniProtKB:O75159] synonym: "CIS-6" EXACT [UniProtKB:O75159] synonym: "Cytokine-inducible SH2 protein 6" EXACT [UniProtKB:O75159] synonym: "Cytokine-inducible SH2-containing protein 5" EXACT [UniProtKB:O75159] synonym: "SOCS-5" EXACT [UniProtKB:O75159] xref: EMBL:AAD40484.1 xref: EMBL:AAH32862.1 xref: EMBL:BAA31646.2 xref: EMBL:CAB66830.1 xref: UniProtKB:O75159 xref: UniProtKB:Q8IYZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019975 ! SOCS5_human relationship: has_function CCO:F0001456 ! epidermal growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002441 ! positive regulation of T-helper 1 cell differentiation relationship: participates_in CCO:P0002443 ! negative regulation of T-helper 2 cell differentiation [Term] id: CCO:B0054609 name: NPHP4_HUMAN def: "Nephrocystin-4" [UniProtKB:O75161] synonym: "Nephroretinin" EXACT [UniProtKB:O75161] xref: EMBL:AAM78558.1 xref: EMBL:AAN06814.1 xref: EMBL:BAA31648.1 xref: UniProtKB:O75161 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018837 ! NPHP4_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054610 name: JHD3A_HUMAN def: "JmjC domain-containing histone demethylation protein 3A" [UniProtKB:O75164] synonym: "EC 1.14.11.-" EXACT [UniProtKB:O75164] synonym: "Jumonji domain-containing protein 2A" EXACT [UniProtKB:O75164] xref: EMBL:AAH02558.1 xref: EMBL:BAA31652.2 xref: EMBL:CAH71021.1 xref: UniProtKB:O75164 xref: UniProtKB:Q5VVB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018362 ! JMJD2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019455 ! h3_1-jmjd2a colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067215 ! JHD3A_HUMAN-Phosphotyrosine547 [Term] id: CCO:B0054611 name: CNOT3_HUMAN def: "CCR4-NOT transcription complex subunit 3" [UniProtKB:O75175] synonym: "CCR4-associated factor 3" EXACT [UniProtKB:O75175] synonym: "Leukocyte receptor cluster member 2" EXACT [UniProtKB:O75175] xref: EMBL:AAF29828.1 xref: EMBL:AAH16474.1 xref: EMBL:BAA31666.2 xref: EMBL:CAB63766.1 xref: UniProtKB:O75175 xref: UniProtKB:Q9NZN7 xref: UniProtKB:Q9UF76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017408 ! CNOT3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015054 ! cnot2-cnot3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0064428 ! CNOT3_HUMAN-Phosphoserine299 [Term] id: CCO:B0054612 name: ANR17_HUMAN def: "Ankyrin repeat domain-containing protein 17" [UniProtKB:O75179] synonym: "Gene trap ankyrin repeat protein" EXACT [UniProtKB:O75179] synonym: "Serologically defined breast cancer antigen NY-BR-16" EXACT [UniProtKB:O75179] xref: EMBL:AAG48253.1 xref: EMBL:AAH04173.1 xref: EMBL:AAH04891.1 xref: EMBL:AAH07747.2 xref: EMBL:AAH19963.1 xref: EMBL:AAH43394.1 xref: EMBL:BAA31672.2 xref: EMBL:BAB15260.1 xref: EMBL:CAD38571.2 xref: UniProtKB:O75179 xref: UniProtKB:Q6PJ85 xref: UniProtKB:Q6PK85 xref: UniProtKB:Q6PKA2 xref: UniProtKB:Q86XI3 xref: UniProtKB:Q8NDR5 xref: UniProtKB:Q96I86 xref: UniProtKB:Q9H288 xref: UniProtKB:Q9H6J9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016977 ! ANKRD17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0065641 ! ANR17_HUMAN-Phosphotyrosine1333 relationship: transforms_into CCO:B0065642 ! ANR17_HUMAN-Phosphoserine2042 relationship: transforms_into CCO:B0065643 ! ANR17_HUMAN-Phosphoserine2045 relationship: transforms_into CCO:B0065644 ! ANR17_HUMAN-Phosphoserine2047 relationship: transforms_into CCO:B0065645 ! ANR17_HUMAN-Phosphoserine2059 relationship: transforms_into CCO:B0065646 ! ANR17_HUMAN-Phosphoserine2067 [Term] id: CCO:B0054613 name: PX11A_HUMAN def: "Peroxisomal membrane protein 11A" [UniProtKB:O75192] synonym: "28 kDa peroxisomal integral membrane protein" EXACT [UniProtKB:O75192] synonym: "HsPEX11p" EXACT [UniProtKB:O75192] synonym: "Peroxin-11A" EXACT [UniProtKB:O75192] synonym: "Peroxisomal biogenesis factor 11A" EXACT [UniProtKB:O75192] synonym: "PEX11alpha" EXACT [UniProtKB:O75192] synonym: "Pex11palpha" EXACT [UniProtKB:O75192] synonym: "PMP28" EXACT [UniProtKB:O75192] xref: EMBL:AAC78658.1 xref: EMBL:AAH09697.1 xref: EMBL:BAA32533.1 xref: EMBL:CAG46843.1 xref: EMBL:CAG46872.1 xref: UniProtKB:O75192 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019562 ! PEX11A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000361 ! integral to peroxisomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054614 name: Z780A_HUMAN def: "Zinc finger protein 780A" [UniProtKB:O75290] xref: EMBL:AAC34327.1 xref: UniProtKB:O75290 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020538 ! ZNF780A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054615 name: RTN2_HUMAN def: "Reticulon-2" [UniProtKB:O75298] synonym: "Neuroendocrine-specific protein-like 1" EXACT [UniProtKB:O75298] synonym: "NSP-like protein 1" EXACT [UniProtKB:O75298] synonym: "NSPLI" EXACT [UniProtKB:O75298] xref: EMBL:AAC14910.1 xref: EMBL:AAC32542.1 xref: EMBL:AAC32543.1 xref: EMBL:AAC32544.1 xref: EMBL:DAA01932.1 xref: EMBL:DAA01933.1 xref: EMBL:DAA01944.1 xref: UniProtKB:O60509 xref: UniProtKB:O75298 xref: UniProtKB:Q7RTM6 xref: UniProtKB:Q7RTN1 xref: UniProtKB:Q7RTN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019812 ! RTN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070260 ! RTN2_HUMAN-Phosphoserine44 [Term] id: CCO:B0054616 name: O75321_HUMAN xref: UniProtKB:O75321 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054617 name: CILP1_HUMAN def: "Cartilage intermediate layer protein 1 precursor" [UniProtKB:O75339] synonym: "Cartilage intermediate-layer protein" EXACT [UniProtKB:O75339] synonym: "CILP-1" EXACT [UniProtKB:O75339] xref: EMBL:AAC33838.1 xref: EMBL:AAF14689.1 xref: EMBL:AAH35776.1 xref: EMBL:AAQ89263.1 xref: EMBL:BAA76692.1 xref: UniProtKB:O75339 xref: UniProtKB:Q6UW99 xref: UniProtKB:Q8IYI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017366 ! CILP_human relationship: has_function CCO:F0000513 ! alkaline phosphatase activity relationship: has_function CCO:F0000937 ! nucleotide diphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001839 ! extracellular matrix part relationship: participates_in CCO:P0002247 ! negative regulation of insulin-like growth factor receptor signaling pathway [Term] id: CCO:B0054618 name: PDCD6_HUMAN def: "Programmed cell death protein 6" [UniProtKB:O75340] synonym: "Apoptosis-linked gene 2 protein" EXACT [UniProtKB:O75340] synonym: "Probable calcium-binding protein ALG-2" EXACT [UniProtKB:O75340] xref: EMBL:AAC27697.1 xref: EMBL:AAF14336.1 xref: EMBL:AAH12384.1 xref: EMBL:AAI06707.1 xref: EMBL:AAV38875.1 xref: UniProtKB:O75340 xref: UniProtKB:Q5TZS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019328 ! PDCD6_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015009 ! hebp2-pdcd6 physical interaction relationship: participates_in CCO:I0015430 ! c14orf32-pdcd6 physical interaction relationship: participates_in CCO:I0015640 ! pdcd6-pdcd6 physical interaction relationship: participates_in CCO:I0015835 ! pdcd6-pef1 physical interaction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals [Term] id: CCO:B0054619 name: GCYB2_HUMAN def: "Guanylate cyclase soluble subunit beta-2" [UniProtKB:O75343] synonym: "EC 4.6.1.2" EXACT [UniProtKB:O75343] synonym: "GCS-beta-2" EXACT [UniProtKB:O75343] xref: EMBL:AAD09440.2 xref: EMBL:AAF66105.1 xref: UniProtKB:O75343 xref: UniProtKB:Q9NZ64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017901 ! GUCY1B2_human relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054620 name: ZN253_HUMAN def: "Zinc finger protein 253" [UniProtKB:O75346] synonym: "BMZF-1" EXACT [UniProtKB:O75346] synonym: "Bone marrow zinc finger 1" EXACT [UniProtKB:O75346] synonym: "Zinc finger protein 411" EXACT [UniProtKB:O75346] xref: EMBL:AAC26844.1 xref: UniProtKB:O75346 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011799 ! ZNF253_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054621 name: O75353_HUMAN def: "Anti-death protein" [UniProtKB:O75353] synonym: "Apoptosis inhibitor" EXACT [UniProtKB:O75353] xref: EMBL:AAC32558.1 xref: EMBL:AAC72344.1 xref: UniProtKB:O75353 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021071 ! IEX-1L_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054622 name: PROP1_HUMAN def: "Homeobox protein prophet of Pit-1" [UniProtKB:O75360] synonym: "Pituitary-specific homeodomain factor" EXACT [UniProtKB:O75360] synonym: "PROP-1" EXACT [UniProtKB:O75360] xref: EMBL:AAC27900.1 xref: EMBL:AAC77453.1 xref: EMBL:AAC77454.1 xref: EMBL:AAH69076.1 xref: UniProtKB:O75360 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019517 ! PROP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003241 ! Wnt receptor signaling pathway through beta-catenin [Term] id: CCO:B0054623 name: ZN217_HUMAN def: "Zinc finger protein 217" [UniProtKB:O75362] xref: EMBL:AAC39895.1 xref: EMBL:AAI13428.1 xref: EMBL:CAC08433.1 xref: UniProtKB:O75362 xref: UniProtKB:Q14DB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020659 ! ZNF217_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072064 ! ZN217_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0072065 ! ZN217_HUMAN-Phosphoserine570 relationship: transforms_into CCO:B0072066 ! ZN217_HUMAN-Phosphoserine795 relationship: transforms_into CCO:B0072067 ! ZN217_HUMAN-Phosphoserine848 [Term] id: CCO:B0054624 name: PITX3_HUMAN def: "Pituitary homeobox 3" [UniProtKB:O75364] synonym: "Homeobox protein PITX3" EXACT [UniProtKB:O75364] xref: EMBL:AAC24502.1 xref: EMBL:AAH11642.1 xref: EMBL:CAH71624.1 xref: UniProtKB:O75364 xref: UniProtKB:Q5VZL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019404 ! PITX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054625 name: H2AY_HUMAN def: "Core histone macro-H2A.1" [UniProtKB:O75367] synonym: "H2A.y" EXACT [UniProtKB:O75367] synonym: "H2A/y" EXACT [UniProtKB:O75367] synonym: "Histone macroH2A1" EXACT [UniProtKB:O75367] synonym: "Medulloblastoma antigen MU-MB-50.205" EXACT [UniProtKB:O75367] synonym: "mH2A1" EXACT [UniProtKB:O75367] xref: EMBL:AAC33433.1 xref: EMBL:AAC33434.1 xref: EMBL:AAC39908.1 xref: EMBL:AAH13331.1 xref: EMBL:AAH95406.1 xref: EMBL:AAN08620.1 xref: EMBL:BAB14565.1 xref: UniProtKB:O75367 xref: UniProtKB:O75377 xref: UniProtKB:Q503A8 xref: UniProtKB:Q7Z5E3 xref: UniProtKB:Q96D41 xref: UniProtKB:Q9H8P3 xref: UniProtKB:Q9UP96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018099 ! H2AFY_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000803 ! dosage compensation relationship: transforms_into CCO:B0066694 ! H2AY_HUMAN-N6-methyllysine18 relationship: transforms_into CCO:B0066695 ! H2AY_HUMAN-N6,N6-dimethyllysine123 relationship: transforms_into CCO:B0066696 ! H2AY_HUMAN-Phosphothreonine129 relationship: transforms_into CCO:B0066697 ! H2AY_HUMAN-Phosphothreonine178 [Term] id: CCO:B0054626 name: NCOR1_HUMAN def: "Nuclear receptor corepressor 1" [UniProtKB:O75376] synonym: "N-CoR" EXACT [UniProtKB:O75376] synonym: "N-CoR1" EXACT [UniProtKB:O75376] xref: EMBL:AAC33550.1 xref: EMBL:BAA75814.1 xref: EMBL:BAA82999.2 xref: UniProtKB:O75376 xref: UniProtKB:Q9UPV5 xref: UniProtKB:Q9UQ18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018731 ! NCOR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017304 ! dach-ncor1-2 physical interaction relationship: participates_in CCO:I0017978 ! ski-ncor1-1 physical interaction relationship: participates_in CCO:I0018282 ! dach-ncor1-1 physical interaction relationship: participates_in CCO:I0018449 ! rdbp-ncor1 physical interaction relationship: participates_in CCO:I0019051 ! atxn1-ncor1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068495 ! NCOR1_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0068496 ! NCOR1_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0068497 ! NCOR1_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0068498 ! NCOR1_HUMAN-Phosphoserine999 relationship: transforms_into CCO:B0068499 ! NCOR1_HUMAN-Phosphoserine1450 relationship: transforms_into CCO:B0068500 ! NCOR1_HUMAN-Phosphoserine1472 relationship: transforms_into CCO:B0068501 ! NCOR1_HUMAN-Phosphoserine1977 relationship: transforms_into CCO:B0068502 ! NCOR1_HUMAN-Phosphoserine2120 relationship: transforms_into CCO:B0068503 ! NCOR1_HUMAN-Phosphoserine2151 relationship: transforms_into CCO:B0068504 ! NCOR1_HUMAN-Phosphoserine2184 relationship: transforms_into CCO:B0068505 ! NCOR1_HUMAN-Phosphotyrosine2432 relationship: transforms_into CCO:B0068506 ! NCOR1_HUMAN-Phosphothreonine2434 relationship: transforms_into CCO:B0068507 ! NCOR1_HUMAN-Phosphoserine2436 relationship: transforms_into CCO:B0068508 ! NCOR1_HUMAN-Phosphoserine2438 [Term] id: CCO:B0054627 name: PEX14_HUMAN def: "Peroxisomal membrane protein PEX14" [UniProtKB:O75381] synonym: "Peroxin-14" EXACT [UniProtKB:O75381] synonym: "Peroxisomal membrane anchor protein PEX14" EXACT [UniProtKB:O75381] synonym: "PTS1 receptor-docking protein" EXACT [UniProtKB:O75381] xref: EMBL:AAC39843.1 xref: EMBL:AAH06327.1 xref: EMBL:BAA36837.1 xref: EMBL:CAD20149.2 xref: EMBL:CAG29317.1 xref: EMBL:CAG46880.1 xref: EMBL:CAH70044.1 xref: EMBL:CAI19198.1 xref: UniProtKB:O75381 xref: UniProtKB:Q8WX51 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019371 ! PEX14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015936 ! pex19-pex14-1 physical interaction relationship: participates_in CCO:I0020103 ! pex14-smarcc2 physical interaction relationship: participates_in CCO:I0020397 ! pex14-med8 physical interaction relationship: participates_in CCO:I0020398 ! pex14-zhx1 physical interaction relationship: participates_in CCO:P0001643 ! negative regulation of gene-specific transcription relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: transforms_into CCO:B0069237 ! PEX14_HUMAN-Phosphoserine335 [Term] id: CCO:B0054628 name: ULK1_HUMAN def: "Serine/threonine-protein kinase ULK1" [UniProtKB:O75385] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O75385] synonym: "Unc-51-like kinase 1" EXACT [UniProtKB:O75385] xref: EMBL:AAC32326.1 xref: EMBL:BAA34442.2 xref: UniProtKB:O75385 xref: UniProtKB:Q9UQ28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020406 ! ULK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000953 ! regulation of autophagy relationship: transforms_into CCO:B0071729 ! ULK1_HUMAN-Phosphoserine556 relationship: transforms_into CCO:B0071730 ! ULK1_HUMAN-Phosphothreonine625 relationship: transforms_into CCO:B0071731 ! ULK1_HUMAN-Phosphoserine638 [Term] id: CCO:B0054629 name: TULP3_HUMAN def: "Tubby-related protein 3" [UniProtKB:O75386] synonym: "Tubby-like protein 3" EXACT [UniProtKB:O75386] xref: EMBL:AAC95431.1 xref: EMBL:AAH32587.1 xref: UniProtKB:O75386 xref: UniProtKB:Q8N5B0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020382 ! TULP3_human relationship: has_function CCO:F0001669 ! phosphatidylinositol-4,5-bisphosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054630 name: GPR32_HUMAN def: "Probable G-protein coupled receptor 32" [UniProtKB:O75388] xref: EMBL:AAC39801.1 xref: EMBL:AAH67453.1 xref: EMBL:AAH67454.1 xref: EMBL:AAH95544.1 xref: UniProtKB:O75388 xref: UniProtKB:Q502U7 xref: UniProtKB:Q6NWS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018015 ! GPR32_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054631 name: DEAF1_HUMAN def: "Deformed epidermal autoregulatory factor 1 homolog" [UniProtKB:O75398] synonym: "Nuclear DEAF-1-related transcriptional regulator" EXACT [UniProtKB:O75398] synonym: "NUDR" EXACT [UniProtKB:O75398] synonym: "Suppressin" EXACT [UniProtKB:O75398] synonym: "Zinc finger MYND domain-containing protein 5" EXACT [UniProtKB:O75398] xref: EMBL:AAB62704.1 xref: EMBL:AAC25715.1 xref: EMBL:AAC25716.1 xref: EMBL:AAC25717.1 xref: EMBL:AAC25718.1 xref: EMBL:AAC25719.1 xref: EMBL:AAC79676.1 xref: EMBL:AAC79677.1 xref: EMBL:AAH53322.1 xref: UniProtKB:O15152 xref: UniProtKB:O75398 xref: UniProtKB:O75399 xref: UniProtKB:O75510 xref: UniProtKB:O75511 xref: UniProtKB:O75512 xref: UniProtKB:O75513 xref: UniProtKB:Q9UET1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017549 ! DEAF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020243 ! ascc2-deaf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064720 ! DEAF1_HUMAN-Phosphoserine176 [Term] id: CCO:B0054632 name: NDK6_HUMAN def: "Nucleoside diphosphate kinase 6" [UniProtKB:O75414] synonym: "EC 2.7.4.6" EXACT [UniProtKB:O75414] synonym: "Inhibitor of p53-induced apoptosis-alpha" EXACT [UniProtKB:O75414] synonym: "IPIA-alpha" EXACT [UniProtKB:O75414] synonym: "NDK 6" EXACT [UniProtKB:O75414] synonym: "NDP kinase 6" EXACT [UniProtKB:O75414] synonym: "nm23-H6" EXACT [UniProtKB:O75414] xref: EMBL:AAC69439.1 xref: EMBL:AAC78463.1 xref: EMBL:AAH01808.1 xref: EMBL:AAH12828.1 xref: UniProtKB:O75414 xref: UniProtKB:Q96E73 xref: UniProtKB:Q9BQ63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018739 ! NME6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000936 ! nucleoside diphosphate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054633 name: PERQ1_HUMAN def: "PERQ amino acid-rich with GYF domain-containing protein 1" [UniProtKB:O75420] synonym: "GRB10-interacting GYF protein 1" EXACT [UniProtKB:O75420] xref: EMBL:AAC78792.1 xref: EMBL:AAL55738.1 xref: EMBL:AAO46888.1 xref: UniProtKB:O75420 xref: UniProtKB:Q6Y7W7 xref: UniProtKB:Q8WZ38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019370 ! GIGYF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018927 ! atn1-perq1 physical interaction relationship: participates_in CCO:P0002755 ! insulin-like growth factor receptor signaling pathway relationship: transforms_into CCO:B0069235 ! PERQ1_HUMAN-Phosphoserine638 [Term] id: CCO:B0054634 name: LRCH4_HUMAN def: "Leucine-rich repeat and calponin homology domain-containing protein 4" [UniProtKB:O75427] synonym: "Leucine-rich neuronal protein" EXACT [UniProtKB:O75427] synonym: "Leucine-rich repeat neuronal protein 4" EXACT [UniProtKB:O75427] xref: EMBL:AAC78793.1 xref: EMBL:AAH07634.1 xref: EMBL:AAH18529.3 xref: UniProtKB:O75427 xref: UniProtKB:Q8WV85 xref: UniProtKB:Q96ID0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018520 ! LRCH4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015104 ! lrch4-rtn4 physical interaction relationship: participates_in CCO:I0015570 ! lrch4-mdfi physical interaction relationship: participates_in CCO:I0020264 ! ca8-lrch4 physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0067774 ! LRCH4_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0067775 ! LRCH4_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0067776 ! LRCH4_HUMAN-Phosphoserine521 [Term] id: CCO:B0054635 name: ZN254_HUMAN def: "Zinc finger protein 254" [UniProtKB:O75437] synonym: "BMZF-5" EXACT [UniProtKB:O75437] synonym: "Bone marrow zinc finger 5" EXACT [UniProtKB:O75437] synonym: "HD-ZNF1" EXACT [UniProtKB:O75437] synonym: "Hematopoietic cell-derived zinc finger protein 1" EXACT [UniProtKB:O75437] synonym: "Zinc finger protein 539" EXACT [UniProtKB:O75437] synonym: "Zinc finger protein 91-like" EXACT [UniProtKB:O75437] xref: EMBL:AAC39913.1 xref: EMBL:AAH43147.2 xref: EMBL:AAI39750.1 xref: EMBL:EAW84960.1 xref: UniProtKB:A4QPC0 xref: UniProtKB:O75437 xref: UniProtKB:Q86XL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020680 ! ZNF254_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072075 ! ZN254_HUMAN-Phosphothreonine625 [Term] id: CCO:B0054636 name: USH2A_HUMAN def: "Usherin precursor" [UniProtKB:O75445] synonym: "Usher syndrome type IIa protein" EXACT [UniProtKB:O75445] synonym: "Usher syndrome type-2A protein" EXACT [UniProtKB:O75445] xref: EMBL:AAC23748.2 xref: EMBL:AAF75819.1 xref: EMBL:AAS47698.1 xref: EMBL:CAH70620.1 xref: EMBL:CAH70621.1 xref: EMBL:CAH71587.1 xref: EMBL:CAH71588.1 xref: EMBL:CAH73621.1 xref: EMBL:CAI19189.1 xref: EMBL:CAI23041.1 xref: UniProtKB:O75445 xref: UniProtKB:Q5VVM9 xref: UniProtKB:Q6S362 xref: UniProtKB:Q9NS27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020423 ! USH2A_human relationship: has_function CCO:F0001649 ! collagen binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0002849 ! maintenance of organ identity relationship: transforms_into CCO:B0071753 ! USH2A_HUMAN-Phosphothreonine1290 relationship: transforms_into CCO:B0071754 ! USH2A_HUMAN-Phosphoserine1424 [Term] id: CCO:B0054637 name: SAP30_HUMAN def: "Histone deacetylase complex subunit SAP30" [UniProtKB:O75446] synonym: "Sin3 corepressor complex subunit SAP30" EXACT [UniProtKB:O75446] synonym: "Sin3-associated polypeptide, 30 kDa" EXACT [UniProtKB:O75446] xref: EMBL:AAC33316.1 xref: EMBL:AAH16757.1 xref: UniProtKB:O75446 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019836 ! SAP30_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018065 ! cir-sap30-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070316 ! SAP30_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0070317 ! SAP30_HUMAN-Phosphoserine138 [Term] id: CCO:B0054638 name: Z324A_HUMAN def: "Zinc finger protein 324A" [UniProtKB:O75467] synonym: "Zinc finger protein ZF5128" EXACT [UniProtKB:O75467] xref: EMBL:AAC33716.1 xref: UniProtKB:O75467 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020521 ! ZNF324_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071939 ! Z324A_HUMAN-Phosphoserine131 [Term] id: CCO:B0054639 name: NR1I2_HUMAN def: "Nuclear receptor subfamily 1 group I member 2" [UniProtKB:O75469] synonym: "Orphan nuclear receptor PAR1" EXACT [UniProtKB:O75469] synonym: "Orphan nuclear receptor PXR" EXACT [UniProtKB:O75469] synonym: "Pregnane X receptor" EXACT [UniProtKB:O75469] synonym: "Steroid and xenobiotic receptor" EXACT [UniProtKB:O75469] synonym: "SXR" EXACT [UniProtKB:O75469] xref: EMBL:AAC64557.1 xref: EMBL:AAC64558.1 xref: EMBL:AAD05436.1 xref: EMBL:AAH17304.2 xref: EMBL:AAK38720.1 xref: EMBL:AAK38721.1 xref: EMBL:AAK38722.1 xref: EMBL:AAM26736.1 xref: EMBL:ABJ52965.1 xref: EMBL:ABJ52966.1 xref: EMBL:ABR09276.1 xref: EMBL:CAB55489.1 xref: EMBL:CAB55490.1 xref: EMBL:CAB55491.1 xref: EMBL:CAB55492.1 xref: EMBL:CAB55493.1 xref: EMBL:CAB55494.1 xref: UniProtKB:O75469 xref: UniProtKB:Q006P5 xref: UniProtKB:Q008C8 xref: UniProtKB:Q96AC7 xref: UniProtKB:Q9UJ22 xref: UniProtKB:Q9UJ23 xref: UniProtKB:Q9UJ24 xref: UniProtKB:Q9UJ25 xref: UniProtKB:Q9UJ26 xref: UniProtKB:Q9UJ27 xref: UniProtKB:Q9UNW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018854 ! NR1I2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0054640 name: LGR5_HUMAN def: "Leucine-rich repeat-containing G-protein coupled receptor 5 precursor" [UniProtKB:O75473] synonym: "G-protein coupled receptor 49" EXACT [UniProtKB:O75473] synonym: "G-protein coupled receptor 67" EXACT [UniProtKB:O75473] synonym: "Orphan G-protein coupled receptor HG38" EXACT [UniProtKB:O75473] xref: EMBL:AAC28019.1 xref: EMBL:AAC77911.1 xref: UniProtKB:O75473 xref: UniProtKB:Q9UP75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018482 ! LGR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054641 name: FRAT2_HUMAN def: "GSK-3-binding protein FRAT2" [UniProtKB:O75474] synonym: "Frat-2" EXACT [UniProtKB:O75474] xref: EMBL:AAC39786.1 xref: EMBL:AAH20165.1 xref: EMBL:BAB39165.1 xref: EMBL:CAI40774.1 xref: UniProtKB:O75474 xref: UniProtKB:Q5JTI0 xref: UniProtKB:Q8WUL9 xref: UniProtKB:Q9BYG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017833 ! FRAT2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054642 name: PSIP1_HUMAN def: "PC4 and SFRS1-interacting protein" [UniProtKB:O75475] synonym: "CLL-associated antigen KW-7" EXACT [UniProtKB:O75475] synonym: "Dense fine speckles 70 kDa protein" EXACT [UniProtKB:O75475] synonym: "DFS 70" EXACT [UniProtKB:O75475] synonym: "Lens epithelium-derived growth factor" EXACT [UniProtKB:O75475] synonym: "Transcriptional coactivator p75/p52" EXACT [UniProtKB:O75475] xref: EMBL:AAB52589.1 xref: EMBL:AAC25167.1 xref: EMBL:AAC97945.1 xref: EMBL:AAC97946.1 xref: EMBL:AAF25870.1 xref: EMBL:AAF25871.1 xref: EMBL:AAH44568.2 xref: EMBL:AAH64135.1 xref: EMBL:AAL99926.1 xref: EMBL:CAH71355.1 xref: EMBL:CAI13287.1 xref: UniProtKB:O00256 xref: UniProtKB:O75475 xref: UniProtKB:O95368 xref: UniProtKB:Q6P391 xref: UniProtKB:Q86YB9 xref: UniProtKB:Q9NZI3 xref: UniProtKB:Q9UER6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019530 ! PSIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069569 ! PSIP1_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0069570 ! PSIP1_HUMAN-Phosphothreonine122 relationship: transforms_into CCO:B0069571 ! PSIP1_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0069572 ! PSIP1_HUMAN-Phosphothreonine134 relationship: transforms_into CCO:B0069573 ! PSIP1_HUMAN-Phosphothreonine141 relationship: transforms_into CCO:B0069574 ! PSIP1_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0069575 ! PSIP1_HUMAN-Phosphoserine273 relationship: transforms_into CCO:B0069576 ! PSIP1_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0069577 ! PSIP1_HUMAN-Phosphothreonine437 [Term] id: CCO:B0054643 name: GPC4_HUMAN def: "Glypican-4 precursor" [UniProtKB:O75487] synonym: "K-glypican" EXACT [UniProtKB:O75487] xref: EMBL:AAC31899.1 xref: EMBL:AAC69991.1 xref: EMBL:AAH17166.1 xref: EMBL:AAL11018.1 xref: EMBL:AAQ88871.1 xref: EMBL:CAB86664.2 xref: EMBL:CAI42076.1 xref: UniProtKB:O75487 xref: UniProtKB:Q6ZMA6 xref: UniProtKB:Q96L43 xref: UniProtKB:Q9NU08 xref: UniProtKB:Q9UJN1 xref: UniProtKB:Q9UPD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017995 ! GPC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054644 name: NDUS3_HUMAN def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor" [UniProtKB:O75489] synonym: "CI-30kD" EXACT [UniProtKB:O75489] synonym: "Complex I-30kD" EXACT [UniProtKB:O75489] synonym: "EC 1.6.5.3" EXACT [UniProtKB:O75489] synonym: "EC 1.6.99.3" EXACT [UniProtKB:O75489] synonym: "NADH-ubiquinone oxidoreductase 30 kDa subunit" EXACT [UniProtKB:O75489] xref: EMBL:AAC27451.1 xref: EMBL:AAD40386.1 xref: EMBL:AAG17541.1 xref: EMBL:AAH00617.1 xref: UniProtKB:O75489 xref: UniProtKB:Q9UNQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018744 ! NDUFS3_human relationship: has_function CCO:F0000447 ! NADH dehydrogenase activity relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0054645 name: DUX2_HUMAN def: "Putative double homeobox protein 2" [UniProtKB:O75505] xref: EMBL:AAC31481.1 xref: UniProtKB:O75505 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017639 ! DUX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054646 name: HSBP1_HUMAN def: "Heat shock factor-binding protein 1" [UniProtKB:O75506] synonym: "Nasopharyngeal carcinoma-associated antigen 13" EXACT [UniProtKB:O75506] synonym: "NPC-A-13" EXACT [UniProtKB:O75506] xref: EMBL:AAC25186.1 xref: EMBL:AAH07515.1 xref: EMBL:AAP73809.1 xref: UniProtKB:O75506 xref: UniProtKB:Q7Z5Z3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018163 ! HSBP1_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054647 name: TNR21_HUMAN def: "Tumor necrosis factor receptor superfamily member 21 precursor" [UniProtKB:O75509] synonym: "Death receptor 6" EXACT [UniProtKB:O75509] synonym: "TNFR-related death receptor 6" EXACT [UniProtKB:O75509] xref: EMBL:AAC34583.1 xref: EMBL:AAH10241.1 xref: EMBL:AAH17730.1 xref: EMBL:AAH21572.1 xref: EMBL:AAP36088.1 xref: EMBL:AAQ88671.1 xref: EMBL:CAB75692.1 xref: UniProtKB:O75509 xref: UniProtKB:Q0D2P5 xref: UniProtKB:Q96D86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020316 ! TNFRSF21_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054648 name: CSDE1_HUMAN def: "Cold shock domain-containing protein E1" [UniProtKB:O75534] synonym: "N-ras upstream gene protein" EXACT [UniProtKB:O75534] synonym: "UNR protein" EXACT [UniProtKB:O75534] xref: EMBL:AAC28634.1 xref: EMBL:AAD27787.1 xref: EMBL:AAH32446.1 xref: EMBL:BAA74908.2 xref: EMBL:CAH18231.1 xref: EMBL:CAI18825.1 xref: EMBL:CAI18826.1 xref: UniProtKB:O75534 xref: UniProtKB:O94961 xref: UniProtKB:Q5TF04 xref: UniProtKB:Q5TF05 xref: UniProtKB:Q68DI9 xref: UniProtKB:Q9Y2S4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017471 ! CSDE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020281 ! csde1-itm1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064546 ! CSDE1_HUMAN-Phosphothreonine444 relationship: transforms_into CCO:B0064547 ! CSDE1_HUMAN-Phosphoserine445 relationship: transforms_into CCO:B0064548 ! CSDE1_HUMAN-Phosphoserine514 [Term] id: CCO:B0054649 name: ZN821_HUMAN def: "Zinc finger protein 821" [UniProtKB:O75541] xref: EMBL:AAC28648.1 xref: EMBL:AAH12116.1 xref: EMBL:EAW59211.1 xref: UniProtKB:A6NK48 xref: UniProtKB:O75541 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020952 ! ZNF821_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015292 ! loc541468-loc55565 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054650 name: SKAP2_HUMAN def: "Src kinase-associated phosphoprotein 2" [UniProtKB:O75563] synonym: "Pyk2/RAFTK-associated protein" EXACT [UniProtKB:O75563] synonym: "Retinoic acid-induced protein 70" EXACT [UniProtKB:O75563] synonym: "SKAP-55HOM" EXACT [UniProtKB:O75563] synonym: "SKAP-HOM" EXACT [UniProtKB:O75563] synonym: "SKAP55 homolog" EXACT [UniProtKB:O75563] synonym: "Src family-associated phosphoprotein 2" EXACT [UniProtKB:O75563] synonym: "Src kinase-associated phosphoprotein 55-related protein" EXACT [UniProtKB:O75563] synonym: "Src-associated adapter protein with PH and SH3 domains" EXACT [UniProtKB:O75563] xref: EMBL:AAC39924.1 xref: EMBL:AAC99296.1 xref: EMBL:AAH02893.1 xref: EMBL:AAH36044.1 xref: EMBL:AAS02033.1 xref: EMBL:AAS07536.1 xref: EMBL:BAA36194.1 xref: EMBL:BAD96605.1 xref: EMBL:CAA06193.1 xref: UniProtKB:O75563 xref: UniProtKB:Q53GP6 xref: UniProtKB:Q75MK6 xref: UniProtKB:Q75MZ4 xref: UniProtKB:Q9UBZ3 xref: UniProtKB:Q9UED8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019927 ! SKAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0070570 ! SKAP2_HUMAN-Phosphotyrosine75 relationship: transforms_into CCO:B0070571 ! SKAP2_HUMAN-Phosphotyrosine151 relationship: transforms_into CCO:B0070572 ! SKAP2_HUMAN-Phosphotyrosine197 relationship: transforms_into CCO:B0070573 ! SKAP2_HUMAN-Phosphotyrosine261 relationship: transforms_into CCO:B0070574 ! SKAP2_HUMAN-Phosphotyrosine325 [Term] id: CCO:B0054651 name: PRKRA_HUMAN def: "Interferon-inducible double stranded RNA-dependent protein kinase activator A" [UniProtKB:O75569] synonym: "PKR-associated protein X" EXACT [UniProtKB:O75569] synonym: "PKR-associating protein X" EXACT [UniProtKB:O75569] synonym: "Protein activator of the interferon-induced protein kinase" EXACT [UniProtKB:O75569] synonym: "Protein kinase, interferon-inducible double stranded RNA-dependent activator" EXACT [UniProtKB:O75569] xref: EMBL:AAC25672.1 xref: EMBL:AAD33099.1 xref: EMBL:AAH09470.1 xref: EMBL:AAP20061.1 xref: EMBL:AAP35907.1 xref: EMBL:AAX88882.1 xref: EMBL:BAD96827.1 xref: EMBL:CAB66550.1 xref: EMBL:CAD38725.1 xref: EMBL:CAG38556.1 xref: UniProtKB:O75569 xref: UniProtKB:Q53G24 xref: UniProtKB:Q6X7T5 xref: UniProtKB:Q8NDK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019510 ! PRKRA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019799 ! prkra-cops6 physical interaction relationship: participates_in CCO:I0019800 ! prkra-gdf9 physical interaction relationship: participates_in CCO:I0019801 ! prkra-prkra physical interaction relationship: participates_in CCO:I0019802 ! prkra-setdb1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0069526 ! PRKRA_HUMAN-Phosphoserine18 [Term] id: CCO:B0054652 name: ITA10_HUMAN def: "Integrin alpha-10 precursor" [UniProtKB:O75578] xref: EMBL:AAC31952.1 xref: EMBL:AAF21944.1 xref: EMBL:AAF61638.1 xref: EMBL:AAQ88691.1 xref: UniProtKB:O75578 xref: UniProtKB:Q6UXJ6 xref: UniProtKB:Q9UHZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018330 ! ITGA10_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0054653 name: KS6A5_HUMAN def: "Ribosomal protein S6 kinase alpha-5" [UniProtKB:O75582] synonym: "90 kDa ribosomal protein S6 kinase 5" EXACT [UniProtKB:O75582] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O75582] synonym: "Nuclear mitogen- and stress-activated protein kinase 1" EXACT [UniProtKB:O75582] synonym: "RSK-like protein kinase" EXACT [UniProtKB:O75582] synonym: "RSKL" EXACT [UniProtKB:O75582] xref: EMBL:AAC31171.1 xref: EMBL:AAC69577.1 xref: EMBL:AAD23915.1 xref: EMBL:AAH17187.1 xref: UniProtKB:O75582 xref: UniProtKB:O95316 xref: UniProtKB:Q96AF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018443 ! RPS6KA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015962 ! rps6ka5-rela physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0067473 ! KS6A5_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0067474 ! KS6A5_HUMAN-Phosphoserine360 relationship: transforms_into CCO:B0067475 ! KS6A5_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0067476 ! KS6A5_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0067477 ! KS6A5_HUMAN-Phosphothreonine581 relationship: transforms_into CCO:B0067478 ! KS6A5_HUMAN-Phosphoserine750 relationship: transforms_into CCO:B0067479 ! KS6A5_HUMAN-Phosphoserine752 relationship: transforms_into CCO:B0067480 ! KS6A5_HUMAN-Phosphoserine758 [Term] id: CCO:B0054654 name: MYCB2_HUMAN def: "Probable E3 ubiquitin-protein ligase MYCBP2" [UniProtKB:O75592] synonym: "EC 6.3.2.-" EXACT [UniProtKB:O75592] synonym: "Myc-binding protein 2" EXACT [UniProtKB:O75592] synonym: "Pam/highwire/rpm-1 protein" EXACT [UniProtKB:O75592] synonym: "Protein associated with Myc" EXACT [UniProtKB:O75592] xref: EMBL:AAC39928.1 xref: EMBL:AAD39842.1 xref: EMBL:AAH37971.1 xref: EMBL:BAA74939.1 xref: EMBL:CAH73736.1 xref: EMBL:CAI16842.1 xref: EMBL:CAI39758.1 xref: EMBL:CAI39759.1 xref: EMBL:EAW80565.1 xref: UniProtKB:A6NJC6 xref: UniProtKB:O75592 xref: UniProtKB:Q5JSX8 xref: UniProtKB:Q5VZN6 xref: UniProtKB:Q6PIB6 xref: UniProtKB:Q9UQ11 xref: UniProtKB:Q9Y6E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018689 ! MYCBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068351 ! MYCB2_HUMAN-Phosphoserine1586 relationship: transforms_into CCO:B0068352 ! MYCB2_HUMAN-Phosphoserine2749 relationship: transforms_into CCO:B0068353 ! MYCB2_HUMAN-Phosphoserine2751 relationship: transforms_into CCO:B0068354 ! MYCB2_HUMAN-Phosphoserine2774 relationship: transforms_into CCO:B0068355 ! MYCB2_HUMAN-Phosphoserine2831 relationship: transforms_into CCO:B0068356 ! MYCB2_HUMAN-Phosphoserine3052 relationship: transforms_into CCO:B0068357 ! MYCB2_HUMAN-Phosphothreonine3883 relationship: transforms_into CCO:B0068358 ! MYCB2_HUMAN-Phosphoserine3893 relationship: transforms_into CCO:B0068359 ! MYCB2_HUMAN-Phosphoserine3894 [Term] id: CCO:B0054655 name: FOXH1_HUMAN def: "Forkhead box protein H1" [UniProtKB:O75593] synonym: "Fast-1" EXACT [UniProtKB:O75593] synonym: "Fast-2" EXACT [UniProtKB:O75593] synonym: "Forkhead activin signal transducer 1" EXACT [UniProtKB:O75593] synonym: "Forkhead activin signal transducer 2" EXACT [UniProtKB:O75593] synonym: "hFAST-1" EXACT [UniProtKB:O75593] xref: EMBL:AAC34303.1 xref: UniProtKB:O75593 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017822 ! FOXH1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001452 ! activin responsive factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054656 name: GCM2_HUMAN def: "Chorion-specific transcription factor GCMb" [UniProtKB:O75603] synonym: "GCM motif protein 2" EXACT [UniProtKB:O75603] synonym: "Glial cells missing homolog 2" EXACT [UniProtKB:O75603] synonym: "hGCMb" EXACT [UniProtKB:O75603] xref: EMBL:AAC33792.1 xref: EMBL:AAC98097.1 xref: EMBL:AAH69603.1 xref: EMBL:AAI17317.1 xref: EMBL:AAI17319.1 xref: EMBL:CAI16225.1 xref: EMBL:CAI20518.1 xref: UniProtKB:O75603 xref: UniProtKB:Q5THN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017895 ! GCM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0054657 name: LFTY1_HUMAN def: "Left-right determination factor 1 precursor" [UniProtKB:O75610] synonym: "Left-right determination factor B" EXACT [UniProtKB:O75610] synonym: "Protein lefty-1" EXACT [UniProtKB:O75610] synonym: "Protein lefty-B" EXACT [UniProtKB:O75610] xref: EMBL:AAC33967.1 xref: EMBL:AAD48144.1 xref: EMBL:AAH27883.1 xref: EMBL:AAQ89232.1 xref: EMBL:BAD96434.1 xref: EMBL:CAI21799.1 xref: UniProtKB:O75610 xref: UniProtKB:Q53H67 xref: UniProtKB:Q5TE94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018477 ! LEFTY1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001462 ! transforming growth factor beta receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0054658 name: PRDM1_HUMAN def: "PR domain zinc finger protein 1" [UniProtKB:O75626] synonym: "Beta-interferon gene positive regulatory domain I-binding factor" EXACT [UniProtKB:O75626] synonym: "BLIMP-1" EXACT [UniProtKB:O75626] synonym: "Positive regulatory domain I-binding factor 1" EXACT [UniProtKB:O75626] synonym: "PR domain-containing protein 1" EXACT [UniProtKB:O75626] synonym: "PRDI-BF1" EXACT [UniProtKB:O75626] synonym: "PRDI-binding factor 1" EXACT [UniProtKB:O75626] xref: EMBL:AAC33300.1 xref: EMBL:AAO45623.1 xref: UniProtKB:O75626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019493 ! PRDM1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019055 ! atxn1-prdm1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054659 name: REM1_HUMAN def: "GTP-binding protein REM 1" [UniProtKB:O75628] synonym: "GTPase-regulating endothelial cell sprouting" EXACT [UniProtKB:O75628] synonym: "Rad and Gem-like GTP-binding protein 1" EXACT [UniProtKB:O75628] xref: EMBL:AAC33132.1 xref: EMBL:AAF74212.1 xref: EMBL:AAH39813.1 xref: EMBL:CAB90274.1 xref: UniProtKB:O75628 xref: UniProtKB:Q9NP57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019668 ! REM1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054660 name: CREG1_HUMAN def: "Protein CREG1 precursor" [UniProtKB:O75629] synonym: "Cellular repressor of E1A-stimulated genes 1" EXACT [UniProtKB:O75629] xref: EMBL:AAC34861.1 xref: EMBL:AAH06786.1 xref: EMBL:AAH08628.1 xref: EMBL:AAQ89430.1 xref: EMBL:BAC04550.1 xref: EMBL:CAB42866.1 xref: UniProtKB:O75629 xref: UniProtKB:Q8N9A3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017452 ! CREG1_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054661 name: FCN3_HUMAN def: "Ficolin-3 precursor" [UniProtKB:O75636] synonym: "Collagen/fibrinogen domain-containing lectin 3 p35" EXACT [UniProtKB:O75636] synonym: "Collagen/fibrinogen domain-containing protein 3" EXACT [UniProtKB:O75636] synonym: "Hakata antigen" EXACT [UniProtKB:O75636] xref: EMBL:AAH20731.1 xref: EMBL:AAU85296.1 xref: EMBL:BAA32277.1 xref: EMBL:BAC11429.1 xref: EMBL:CAG33089.1 xref: EMBL:CAI14774.1 xref: UniProtKB:O75636 xref: UniProtKB:Q6IBJ5 xref: UniProtKB:Q8WW86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017772 ! FCN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066156 ! FCN3_HUMAN-Hydroxyproline50 relationship: transforms_into CCO:B0066157 ! FCN3_HUMAN-Hydroxyproline53 relationship: transforms_into CCO:B0066158 ! FCN3_HUMAN-Hydroxyproline59 relationship: transforms_into CCO:B0066159 ! FCN3_HUMAN-Hydroxyproline65 relationship: transforms_into CCO:B0066160 ! FCN3_HUMAN-Hydroxyproline68 relationship: transforms_into CCO:B0066161 ! FCN3_HUMAN-Hydroxyproline77 [Term] id: CCO:B0054662 name: UTP20_HUMAN def: "Small subunit processome component 20 homolog" [UniProtKB:O75691] synonym: "Down-regulated in metastasis protein" EXACT [UniProtKB:O75691] synonym: "NNP73" EXACT [UniProtKB:O75691] synonym: "Novel nucleolar protein 73" EXACT [UniProtKB:O75691] synonym: "Protein Key-1A6" EXACT [UniProtKB:O75691] xref: EMBL:AAG35208.1 xref: EMBL:CAA07243.1 xref: UniProtKB:O75691 xref: UniProtKB:Q9H3H4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020427 ! UTP20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016533 ! ikbkg-drim physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0071767 ! UTP20_HUMAN-Phosphoserine788 relationship: transforms_into CCO:B0071768 ! UTP20_HUMAN-Phosphothreonine1741 relationship: transforms_into CCO:B0071769 ! UTP20_HUMAN-Phosphothreonine2064 relationship: transforms_into CCO:B0071770 ! UTP20_HUMAN-Phosphoserine2637 [Term] id: CCO:B0054663 name: P3C2G_HUMAN def: "Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide" [UniProtKB:O75747] synonym: "EC 2.7.1.154" EXACT [UniProtKB:O75747] synonym: "Phosphoinositide 3-Kinase-C2-gamma" EXACT [UniProtKB:O75747] synonym: "PI3K-C2gamma" EXACT [UniProtKB:O75747] synonym: "PtdIns-3-kinase C2 gamma" EXACT [UniProtKB:O75747] xref: EMBL:CAA03853.1 xref: UniProtKB:O75747 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019275 ! PIK3C2G_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003116 ! phosphatidylinositol phosphate kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0005554 ! phosphatidylinositol-4-phosphate 3-kinase activity relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0069023 ! P3C2G_HUMAN-Phosphotyrosine419 [Term] id: CCO:B0054664 name: O75761_HUMAN def: "Ranbp3 protein" [UniProtKB:O75761] xref: EMBL:CAA69958.1 xref: UniProtKB:O75761 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021072 ! ranbp3_human relationship: has_function CCO:F0001985 ! Ran GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000260 ! nuclear pore relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054665 name: PALM_HUMAN def: "Paralemmin" [UniProtKB:O75781] xref: EMBL:AAC62429.1 xref: EMBL:AAH32449.1 xref: EMBL:BAA13400.1 xref: EMBL:CAA76151.1 xref: EMBL:CAA76152.1 xref: EMBL:CAB37400.1 xref: EMBL:CAB37401.1 xref: UniProtKB:O43359 xref: UniProtKB:O75781 xref: UniProtKB:O95673 xref: UniProtKB:Q92559 xref: UniProtKB:Q9UPJ4 xref: UniProtKB:Q9UQS2 xref: UniProtKB:Q9UQS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019297 ! PALM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0069085 ! PALM_HUMAN-Phosphothreonine141 relationship: transforms_into CCO:B0069086 ! PALM_HUMAN-Phosphothreonine145 relationship: transforms_into CCO:B0069087 ! PALM_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0069088 ! PALM_HUMAN-Phosphothreonine158 relationship: transforms_into CCO:B0069089 ! PALM_HUMAN-Phosphoserine346 relationship: transforms_into CCO:B0069090 ! PALM_HUMAN-Phosphothreonine367 relationship: transforms_into CCO:B0069091 ! PALM_HUMAN-Phosphoserine369 [Term] id: CCO:B0054666 name: RHBL1_HUMAN def: "Rhomboid-related protein 1" [UniProtKB:O75783] synonym: "EC 3.4.21.105" EXACT [UniProtKB:O75783] synonym: "Rhomboid-like protein 1" EXACT [UniProtKB:O75783] synonym: "RRP" EXACT [UniProtKB:O75783] xref: EMBL:AAI20875.1 xref: EMBL:AAI20876.1 xref: EMBL:AAK61241.1 xref: EMBL:CAA76629.1 xref: EMBL:CAC00640.1 xref: UniProtKB:O75783 xref: UniProtKB:Q0VAX4 xref: UniProtKB:Q9NQ85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019707 ! RHBDL1_human relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054667 name: RENR_HUMAN def: "Renin receptor precursor" [UniProtKB:O75787] synonym: "ATP6M8-9" EXACT [UniProtKB:O75787] synonym: "ATPase H(+)-transporting lysosomal accessory protein 2" EXACT [UniProtKB:O75787] synonym: "ATPase H(+)-transporting lysosomal-interacting protein 2" EXACT [UniProtKB:O75787] synonym: "Embryonic liver differentiation factor 10" EXACT [UniProtKB:O75787] synonym: "ER-localized type I transmembrane adaptor" EXACT [UniProtKB:O75787] synonym: "N14F" EXACT [UniProtKB:O75787] synonym: "Renin/prorenin receptor" EXACT [UniProtKB:O75787] synonym: "V-ATPase M8.9 subunit" EXACT [UniProtKB:O75787] synonym: "Vacuolar ATP synthase membrane sector-associated protein M8-9" EXACT [UniProtKB:O75787] xref: EMBL:AAG44564.1 xref: EMBL:AAH10395.1 xref: EMBL:AAH84541.1 xref: EMBL:AAK83467.1 xref: EMBL:AAM47531.1 xref: EMBL:AAQ13511.1 xref: EMBL:AAR06910.1 xref: EMBL:BAC11582.1 xref: EMBL:CAA76984.1 xref: EMBL:CAB43210.1 xref: UniProtKB:O75787 xref: UniProtKB:Q5QTQ7 xref: UniProtKB:Q6T7F5 xref: UniProtKB:Q8NBP3 xref: UniProtKB:Q8NG15 xref: UniProtKB:Q96FV6 xref: UniProtKB:Q96LB5 xref: UniProtKB:Q9H2P8 xref: UniProtKB:Q9UG89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019671 ! ATP6AP2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002209 ! regulation of MAPKKK cascade [Term] id: CCO:B0054668 name: GRAP2_HUMAN def: "GRB2-related adapter protein 2" [UniProtKB:O75791] synonym: "Adapter protein GRID" EXACT [UniProtKB:O75791] synonym: "GRB-2-like protein" EXACT [UniProtKB:O75791] synonym: "GRB2L" EXACT [UniProtKB:O75791] synonym: "GRBLG" EXACT [UniProtKB:O75791] synonym: "GRBX" EXACT [UniProtKB:O75791] synonym: "Grf-40" EXACT [UniProtKB:O75791] synonym: "Grf40 adapter protein" EXACT [UniProtKB:O75791] synonym: "Growth factor receptor-binding protein" EXACT [UniProtKB:O75791] synonym: "Hematopoietic cell-associated adapter protein GrpL" EXACT [UniProtKB:O75791] synonym: "P38" EXACT [UniProtKB:O75791] synonym: "Protein GADS" EXACT [UniProtKB:O75791] synonym: "SH3-SH2-SH3 adapter Mona" EXACT [UniProtKB:O75791] xref: EMBL:AAC69273.1 xref: EMBL:AAD04926.1 xref: EMBL:AAD13027.1 xref: EMBL:AAD41782.1 xref: EMBL:AAF31758.1 xref: EMBL:AAF60320.1 xref: EMBL:AAH25692.1 xref: EMBL:AAH26002.1 xref: EMBL:AAL58573.1 xref: EMBL:CAA09757.1 xref: EMBL:CAA77021.1 xref: EMBL:CAG30384.1 xref: EMBL:CAI42713.1 xref: UniProtKB:O43726 xref: UniProtKB:O75791 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018050 ! GRAP2_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0014968 ! grap2-zbtb7b physical interaction relationship: participates_in CCO:I0015047 ! c1orf165-grap2 physical interaction relationship: participates_in CCO:I0015090 ! grap2-hnrpk physical interaction relationship: participates_in CCO:I0015187 ! grap2-rbpms physical interaction relationship: participates_in CCO:I0015507 ! grap2-ywhae physical interaction relationship: participates_in CCO:I0015569 ! gfap-grap2 physical interaction relationship: participates_in CCO:I0015665 ! grap2-krtap4_12 physical interaction relationship: participates_in CCO:I0015828 ! grap2-stambp physical interaction relationship: participates_in CCO:I0015853 ! grap2-lcp2 physical interaction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0066576 ! GRAP2_HUMAN-Phosphotyrosine45 relationship: transforms_into CCO:B0066577 ! GRAP2_HUMAN-Phosphothreonine262 [Term] id: CCO:B0054669 name: O75806_HUMAN def: "HOXA-9B" [UniProtKB:O75806] xref: EMBL:AAC23705.1 xref: UniProtKB:O75806 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011838 ! HOXA-9_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054670 name: O75810_HUMAN def: "ErbB-3 R1" [UniProtKB:O75810] xref: EMBL:AAC39857.1 xref: UniProtKB:O75810 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021073 ! c-erbB-3_human relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0054671 name: ZN189_HUMAN def: "Zinc finger protein 189" [UniProtKB:O75820] xref: EMBL:AAC25909.1 xref: EMBL:AAC25910.1 xref: EMBL:AAC39798.1 xref: EMBL:AAC39799.1 xref: EMBL:AAC39800.1 xref: EMBL:AAD50527.1 xref: EMBL:AAD50528.1 xref: EMBL:AAH92425.1 xref: EMBL:CAI14611.1 xref: UniProtKB:O75802 xref: UniProtKB:O75820 xref: UniProtKB:Q5T7D9 xref: UniProtKB:Q9UBL4 xref: UniProtKB:Q9UPE9 xref: UniProtKB:Q9UPF0 xref: UniProtKB:Q9UPF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020646 ! ZNF189_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054672 name: LECT1_HUMAN def: "Chondromodulin-1 precursor" [UniProtKB:O75829] synonym: "ChM-I" EXACT [UniProtKB:O75829] synonym: "Chondromodulin-I" EXACT [UniProtKB:O75829] synonym: "Leukocyte cell-derived chemotaxin 1" EXACT [UniProtKB:O75829] xref: EMBL:AAC98971.1 xref: EMBL:BAA33443.1 xref: EMBL:BAA77384.1 xref: EMBL:BAA86262.1 xref: UniProtKB:O75829 xref: UniProtKB:Q9UM18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018467 ! LECT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001355 ! negative regulation of vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:B0054673 name: KLF7_HUMAN def: "Krueppel-like factor 7" [UniProtKB:O75840] synonym: "Ubiquitous krueppel-like factor" EXACT [UniProtKB:O75840] xref: EMBL:BAA33521.1 xref: EMBL:CAG46909.1 xref: UniProtKB:O75840 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018422 ! KLF7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054674 name: TNF13_HUMAN def: "Tumor necrosis factor ligand superfamily member 13 precursor" [UniProtKB:O75888] synonym: "A proliferation-inducing ligand" EXACT [UniProtKB:O75888] synonym: "APRIL" EXACT [UniProtKB:O75888] synonym: "CD256 antigen" EXACT [UniProtKB:O75888] synonym: "TALL-2" EXACT [UniProtKB:O75888] synonym: "TNF- and APOL-related leukocyte expressed ligand 2" EXACT [UniProtKB:O75888] synonym: "TNF-related death ligand 1" EXACT [UniProtKB:O75888] synonym: "TRDL-1" EXACT [UniProtKB:O75888] xref: EMBL:AAC61312.1 xref: EMBL:AAD29422.1 xref: EMBL:AAF01321.1 xref: EMBL:AAF59828.1 xref: EMBL:AAF59829.1 xref: EMBL:AAF59830.1 xref: EMBL:AAH08042.1 xref: EMBL:AAQ89239.1 xref: EMBL:AAV38368.1 xref: UniProtKB:O75888 xref: UniProtKB:Q96HV6 xref: UniProtKB:Q9P1M8 xref: UniProtKB:Q9P1M9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020300 ! TNFSF13_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0017364 ! tac1-april physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002809 ! positive regulation of isotype switching to IgA isotypes [Term] id: CCO:B0054675 name: O75889_HUMAN def: "Killer cell lectin-like receptor subfamily A member 1 (NK receptor Ly- 49L)." [UniProtKB:O75889] xref: EMBL:AAC35898.1 xref: EMBL:AAH69672.1 xref: EMBL:AAH69734.1 xref: EMBL:AAI01472.1 xref: EMBL:AAI01474.1 xref: EMBL:EAW96193.1 xref: UniProtKB:O75889 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021074 ! KLRA1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054676 name: RASF9_HUMAN def: "Ras association domain-containing protein 9" [UniProtKB:O75901] synonym: "P-CIP1" EXACT [UniProtKB:O75901] synonym: "PAM COOH-terminal interactor protein 1" EXACT [UniProtKB:O75901] synonym: "Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor" EXACT [UniProtKB:O75901] xref: EMBL:AAD03250.1 xref: EMBL:AAH31589.1 xref: UniProtKB:O75901 xref: UniProtKB:Q8N5U8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022558 ! RASSF9_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000738 ! trans-Golgi network transport vesicle membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054677 name: DGKI_HUMAN def: "Diacylglycerol kinase iota" [UniProtKB:O75912] synonym: "DAG kinase iota" EXACT [UniProtKB:O75912] synonym: "DGK-iota" EXACT [UniProtKB:O75912] synonym: "Diglyceride kinase iota" EXACT [UniProtKB:O75912] synonym: "EC 2.7.1.107" EXACT [UniProtKB:O75912] xref: EMBL:AAC62010.1 xref: EMBL:AAF43006.1 xref: UniProtKB:O75912 xref: UniProtKB:Q9NZ49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017570 ! DGKI_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064752 ! DGKI_HUMAN-Phosphoserine1049 relationship: transforms_into CCO:B0064753 ! DGKI_HUMAN-Phosphotyrosine1053 [Term] id: CCO:B0054678 name: RGS9_HUMAN def: "Regulator of G-protein signaling 9" [UniProtKB:O75916] synonym: "RGS9" EXACT [UniProtKB:O75916] xref: EMBL:AAC25430.1 xref: EMBL:AAC64040.1 xref: EMBL:AAG09311.1 xref: EMBL:AAG09312.1 xref: EMBL:AAM12646.1 xref: EMBL:AAM12647.1 xref: EMBL:AAT79493.1 xref: EMBL:AAT79494.1 xref: UniProtKB:O75573 xref: UniProtKB:O75916 xref: UniProtKB:Q696R2 xref: UniProtKB:Q8TD64 xref: UniProtKB:Q8TD65 xref: UniProtKB:Q9HC32 xref: UniProtKB:Q9HC33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019706 ! RGS9_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0054679 name: SPF30_HUMAN def: "Survival of motor neuron-related-splicing factor 30" [UniProtKB:O75940] synonym: "30 kDa splicing factor SMNrp" EXACT [UniProtKB:O75940] synonym: "SMN-related protein" EXACT [UniProtKB:O75940] synonym: "Survival motor neuron domain-containing protein 1" EXACT [UniProtKB:O75940] xref: EMBL:AAC64086.1 xref: EMBL:AAC84148.1 xref: EMBL:AAH11234.1 xref: EMBL:CAI15482.1 xref: UniProtKB:O75940 xref: UniProtKB:Q5T3K6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020012 ! SMNDC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019348 ! smndc1-kpnb1 physical interaction relationship: participates_in CCO:I0019349 ! smndc1-kpnb1-2 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0070797 ! SPF30_HUMAN-Phosphoserine201 [Term] id: CCO:B0054680 name: CABYR_HUMAN def: "Calcium-binding tyrosine phosphorylation-regulated protein" [UniProtKB:O75952] synonym: "Calcium-binding protein 86" EXACT [UniProtKB:O75952] synonym: "Cancer/testis antigen 88" EXACT [UniProtKB:O75952] synonym: "CT88" EXACT [UniProtKB:O75952] synonym: "Fibrousheathin II" EXACT [UniProtKB:O75952] synonym: "Fibrousheathin-2" EXACT [UniProtKB:O75952] synonym: "FSP-2" EXACT [UniProtKB:O75952] synonym: "Testis-specific calcium-binding protein CBP86" EXACT [UniProtKB:O75952] xref: EMBL:AAC35373.1 xref: EMBL:AAG01891.1 xref: EMBL:AAG17889.1 xref: EMBL:AAG17890.1 xref: EMBL:AAG17891.1 xref: EMBL:AAH11996.1 xref: EMBL:AAL56051.1 xref: UniProtKB:O75952 xref: UniProtKB:Q8WXW5 xref: UniProtKB:Q9HAY3 xref: UniProtKB:Q9HAY4 xref: UniProtKB:Q9HAY5 xref: UniProtKB:Q9HCY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017207 ! CABYR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064035 ! CABYR_HUMAN-Phosphothreonine151 relationship: transforms_into CCO:B0064036 ! CABYR_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0064037 ! CABYR_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0064038 ! CABYR_HUMAN-Phosphoserine359 relationship: transforms_into CCO:B0064039 ! CABYR_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0064040 ! CABYR_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0064041 ! CABYR_HUMAN-Phosphoserine461 relationship: transforms_into CCO:B0064042 ! CABYR_HUMAN-Phosphoserine469 [Term] id: CCO:B0054681 name: TRIO_HUMAN def: "Triple functional domain protein" [UniProtKB:O75962] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O75962] synonym: "PTPRF-interacting protein" EXACT [UniProtKB:O75962] xref: EMBL:AAC34245.1 xref: EMBL:AAC43042.1 xref: EMBL:AAH17268.1 xref: EMBL:AAH35585.1 xref: EMBL:BAD18570.1 xref: EMBL:BAD92991.1 xref: UniProtKB:O75962 xref: UniProtKB:Q13458 xref: UniProtKB:Q59EQ7 xref: UniProtKB:Q6PJC9 xref: UniProtKB:Q6ZN05 xref: UniProtKB:Q8IWK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020360 ! TRIO_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017469 ! disc1-trio physical interaction relationship: participates_in CCO:I0017470 ! disc1-trio-1 physical interaction relationship: participates_in CCO:I0017471 ! disc1-trio-2 physical interaction relationship: participates_in CCO:I0017472 ! exoc1-trio physical interaction relationship: participates_in CCO:I0020257 ! blmh-trio physical interaction relationship: participates_in CCO:P0000725 ! transmembrane receptor protein tyrosine phosphatase signaling pathway relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0071562 ! TRIO_HUMAN-Phosphothreonine1486 relationship: transforms_into CCO:B0071563 ! TRIO_HUMAN-Phosphothreonine1844 [Term] id: CCO:B0054682 name: AKAP3_HUMAN def: "A-kinase anchor protein 3" [UniProtKB:O75969] synonym: "A-kinase anchor protein 110 kDa" EXACT [UniProtKB:O75969] synonym: "AKAP 110" EXACT [UniProtKB:O75969] synonym: "Cancer/testis antigen 82" EXACT [UniProtKB:O75969] synonym: "CT82" EXACT [UniProtKB:O75969] synonym: "Fibrous sheath protein of 95 kDa" EXACT [UniProtKB:O75969] synonym: "Fibrousheathin I" EXACT [UniProtKB:O75969] synonym: "Fibrousheathin-1" EXACT [UniProtKB:O75969] synonym: "FSP95" EXACT [UniProtKB:O75969] synonym: "PRKA3" EXACT [UniProtKB:O75969] synonym: "Protein kinase A-anchoring protein 3" EXACT [UniProtKB:O75969] synonym: "Sperm oocyte-binding protein" EXACT [UniProtKB:O75969] xref: EMBL:AAC35854.1 xref: EMBL:AAC63371.1 xref: EMBL:AAD21218.1 xref: UniProtKB:O75945 xref: UniProtKB:O75969 xref: UniProtKB:Q9UM61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016943 ! AKAP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: transforms_into CCO:B0065528 ! AKAP3_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0065529 ! AKAP3_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0065530 ! AKAP3_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0065531 ! AKAP3_HUMAN-Phosphotyrosine404 relationship: transforms_into CCO:B0065532 ! AKAP3_HUMAN-Phosphoserine440 relationship: transforms_into CCO:B0065533 ! AKAP3_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0065534 ! AKAP3_HUMAN-Phosphoserine635 relationship: transforms_into CCO:B0065535 ! AKAP3_HUMAN-Phosphoserine636 [Term] id: CCO:B0054683 name: SNPC5_HUMAN def: "snRNA-activating protein complex subunit 5" [UniProtKB:O75971] synonym: "Small nuclear RNA-activating complex polypeptide 5" EXACT [UniProtKB:O75971] synonym: "SNAPc 19 kDa subunit" EXACT [UniProtKB:O75971] synonym: "SNAPc subunit 5" EXACT [UniProtKB:O75971] synonym: "snRNA-activating protein complex 19 kDa subunit" EXACT [UniProtKB:O75971] xref: EMBL:AAC61873.1 xref: EMBL:AAH14315.1 xref: UniProtKB:O75971 xref: UniProtKB:Q96CF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019968 ! SNAPC5_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015503 ! batf-snapc5 physical interaction relationship: participates_in CCO:I0015587 ! c6_1a-snapc5 physical interaction relationship: participates_in CCO:I0015715 ! nmi-snapc5 physical interaction relationship: participates_in CCO:I0015817 ! nol4-snapc5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054684 name: OR2B3_HUMAN def: "Putative olfactory receptor 2B3" [UniProtKB:O76000] synonym: "Hs6M1-1" EXACT [UniProtKB:O76000] synonym: "Olfactory receptor 6-4" EXACT [UniProtKB:O76000] synonym: "Olfactory receptor OR6-14" EXACT [UniProtKB:O76000] synonym: "OR6-4" EXACT [UniProtKB:O76000] xref: EMBL:AAK95117.1 xref: EMBL:CAA18782.1 xref: EMBL:CAC20462.1 xref: EMBL:CAC20463.1 xref: EMBL:CAC20464.1 xref: EMBL:CAC20465.1 xref: EMBL:CAC20466.1 xref: EMBL:CAC20467.1 xref: EMBL:CAC20468.1 xref: EMBL:CAC20469.1 xref: EMBL:CAC20470.1 xref: EMBL:CAC20471.1 xref: EMBL:CAI17592.1 xref: EMBL:CAI18246.1 xref: EMBL:CAI41771.1 xref: EMBL:DAA04834.1 xref: UniProtKB:O76000 xref: UniProtKB:Q5ST41 xref: UniProtKB:Q96R13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019085 ! OR2B3P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054685 name: OR2J3_HUMAN def: "Olfactory receptor 2J3" [UniProtKB:O76001] synonym: "Hs6M1-3" EXACT [UniProtKB:O76001] synonym: "Olfactory receptor 6-6" EXACT [UniProtKB:O76001] synonym: "Olfactory receptor OR6-16" EXACT [UniProtKB:O76001] synonym: "OR6-6" EXACT [UniProtKB:O76001] xref: EMBL:AAK95115.1 xref: EMBL:CAA18783.1 xref: EMBL:CAC20472.1 xref: EMBL:CAC20473.1 xref: EMBL:CAC20474.1 xref: EMBL:CAC20475.1 xref: EMBL:CAC20476.1 xref: EMBL:CAC20477.1 xref: EMBL:CAC20478.1 xref: EMBL:CAC21440.1 xref: EMBL:CAC21441.1 xref: EMBL:CAC21442.1 xref: EMBL:CAC21443.1 xref: EMBL:CAC21444.1 xref: EMBL:CAI17594.1 xref: EMBL:CAI41773.1 xref: EMBL:CAM26133.1 xref: EMBL:DAA04835.1 xref: UniProtKB:O76001 xref: UniProtKB:Q6IF25 xref: UniProtKB:Q96R15 xref: UniProtKB:Q9GZK5 xref: UniProtKB:Q9GZL4 xref: UniProtKB:Q9GZL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019102 ! OR2J3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054686 name: OR2J2_HUMAN def: "Olfactory receptor 2J2" [UniProtKB:O76002] synonym: "Hs6M1-6" EXACT [UniProtKB:O76002] synonym: "Olfactory receptor 6-8" EXACT [UniProtKB:O76002] synonym: "Olfactory receptor OR6-19" EXACT [UniProtKB:O76002] synonym: "OR6-8" EXACT [UniProtKB:O76002] xref: EMBL:AAH69121.1 xref: EMBL:AAI08897.1 xref: EMBL:AAI08898.1 xref: EMBL:AAI08899.1 xref: EMBL:AAI08900.1 xref: EMBL:CAA18784.1 xref: EMBL:CAC20491.1 xref: EMBL:CAC20492.1 xref: EMBL:CAC20493.1 xref: EMBL:CAC20494.1 xref: EMBL:CAC20495.1 xref: EMBL:CAC20496.1 xref: EMBL:CAC20497.1 xref: EMBL:CAC20498.1 xref: EMBL:CAC20499.1 xref: EMBL:CAC20500.1 xref: EMBL:CAC20501.1 xref: EMBL:CAC20502.1 xref: EMBL:CAC20503.1 xref: EMBL:CAI17596.1 xref: EMBL:CAI18104.1 xref: EMBL:CAI18469.1 xref: EMBL:CAM26135.1 xref: EMBL:CAQ07385.1 xref: EMBL:DAA04836.1 xref: UniProtKB:A6NCU9 xref: UniProtKB:A6NLD0 xref: UniProtKB:O76002 xref: UniProtKB:Q32N09 xref: UniProtKB:Q5ST39 xref: UniProtKB:Q5SUJ6 xref: UniProtKB:Q6IF24 xref: UniProtKB:Q9GZK2 xref: UniProtKB:Q9GZL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019101 ! OR2J2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054687 name: WFS1_HUMAN def: "Wolframin" [UniProtKB:O76024] xref: EMBL:AAC64943.1 xref: EMBL:AAH30130.1 xref: EMBL:CAA77022.1 xref: UniProtKB:O76024 xref: UniProtKB:Q8N6I3 xref: UniProtKB:Q9UNW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020475 ! WFS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0020351 ! itgb3bp-wfs1 physical interaction relationship: participates_in CCO:P0000684 ! ER overload response relationship: participates_in CCO:P0002151 ! negative regulation of programmed cell death relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: transforms_into CCO:B0071842 ! WFS1_HUMAN-Phosphoserine32 [Term] id: CCO:B0054688 name: NCTR1_HUMAN def: "Natural cytotoxicity triggering receptor 1 precursor" [UniProtKB:O76036] synonym: "CD335 antigen" EXACT [UniProtKB:O76036] synonym: "hNKp46" EXACT [UniProtKB:O76036] synonym: "Lymphocyte antigen 94 homolog" EXACT [UniProtKB:O76036] synonym: "Natural killer cell p46-related protein" EXACT [UniProtKB:O76036] synonym: "NK cell-activating receptor" EXACT [UniProtKB:O76036] synonym: "NK-p46" EXACT [UniProtKB:O76036] synonym: "NKp46" EXACT [UniProtKB:O76036] xref: EMBL:AAH64806.1 xref: EMBL:AAQ54328.1 xref: EMBL:CAA04714.1 xref: EMBL:CAA06872.1 xref: EMBL:CAA06873.1 xref: EMBL:CAA06874.1 xref: UniProtKB:O76016 xref: UniProtKB:O76017 xref: UniProtKB:O76018 xref: UniProtKB:O76036 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018732 ! NCR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002052 ! regulation of natural killer cell mediated cytotoxicity [Term] id: CCO:B0054689 name: NEBL_HUMAN def: "Nebulette" [UniProtKB:O76041] synonym: "Actin-binding Z-disk protein" EXACT [UniProtKB:O76041] xref: EMBL:AAF24858.1 xref: EMBL:AAI10454.1 xref: EMBL:CAA76130.1 xref: EMBL:CAA76810.1 xref: EMBL:CAC19642.1 xref: UniProtKB:O76041 xref: UniProtKB:Q2TBD0 xref: UniProtKB:Q9UIC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018746 ! NEBL_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001325 ! regulation of actin filament length [Term] id: CCO:B0054690 name: S14L2_HUMAN def: "SEC14-like protein 2" [UniProtKB:O76054] synonym: "Alpha-tocopherol-associated protein" EXACT [UniProtKB:O76054] synonym: "hTAP" EXACT [UniProtKB:O76054] synonym: "SPF" EXACT [UniProtKB:O76054] synonym: "Squalene transfer protein" EXACT [UniProtKB:O76054] synonym: "Supernatant protein factor" EXACT [UniProtKB:O76054] synonym: "TAP" EXACT [UniProtKB:O76054] xref: EMBL:AAF19256.1 xref: EMBL:BAA86500.2 xref: EMBL:CAB51405.1 xref: EMBL:CAG30457.1 xref: UniProtKB:O76054 xref: UniProtKB:Q9ULN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019820 ! SEC14L2_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0001898 ! vitamin E binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002385 ! regulation of cholesterol biosynthetic process relationship: participates_in CCO:P0002387 ! positive regulation of cholesterol biosynthetic process relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0054691 name: CIAO1_HUMAN def: "Protein CIAO1" [UniProtKB:O76071] synonym: "WD repeat-containing protein 39" EXACT [UniProtKB:O76071] xref: EMBL:AAC23493.1 xref: EMBL:AAC24948.1 xref: EMBL:AAH01395.1 xref: EMBL:AAH32812.1 xref: EMBL:ABK41108.1 xref: EMBL:BAD96977.1 xref: EMBL:CAG33083.1 xref: UniProtKB:A0MNN9 xref: UniProtKB:O76071 xref: UniProtKB:Q53FM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017361 ! CIAO1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015049 ! ccdc7-wdr39 physical interaction relationship: participates_in CCO:I0015089 ! cgi_128-wdr39 physical interaction relationship: participates_in CCO:I0015810 ! flj22875-wdr39 physical interaction relationship: participates_in CCO:I0020569 ! golph2-wdr39 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0054692 name: PDE5A_HUMAN def: "cGMP-specific 3',5'-cyclic phosphodiesterase" [UniProtKB:O76074] synonym: "CGB-PDE" EXACT [UniProtKB:O76074] synonym: "cGMP-binding cGMP-specific phosphodiesterase" EXACT [UniProtKB:O76074] synonym: "EC 3.1.4.35" EXACT [UniProtKB:O76074] xref: EMBL:AAC63967.1 xref: EMBL:AAC63968.1 xref: EMBL:AAI26234.1 xref: EMBL:AAP21809.1 xref: EMBL:AAP31235.1 xref: EMBL:BAA28945.1 xref: EMBL:BAA33372.2 xref: EMBL:BAA81667.1 xref: EMBL:CAA06170.1 xref: UniProtKB:A0AV69 xref: UniProtKB:O75026 xref: UniProtKB:O75887 xref: UniProtKB:O76074 xref: UniProtKB:Q86UI0 xref: UniProtKB:Q86V66 xref: UniProtKB:Q9Y6Z6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019342 ! PDE5A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069183 ! PDE5A_HUMAN-Phosphoserine102 [Term] id: CCO:B0054693 name: PDE9A_HUMAN def: "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A" [UniProtKB:O76083] synonym: "EC 3.1.4.35" EXACT [UniProtKB:O76083] xref: EMBL:AAC26723.1 xref: EMBL:AAC26724.1 xref: EMBL:AAC26725.1 xref: EMBL:AAC26726.1 xref: EMBL:AAC39778.1 xref: EMBL:AAH09047.1 xref: EMBL:AAO34685.1 xref: EMBL:AAO34686.1 xref: EMBL:AAO34687.1 xref: EMBL:AAO34688.1 xref: EMBL:AAO34689.1 xref: EMBL:AAO34690.1 xref: EMBL:AAO34691.1 xref: EMBL:AAO34692.1 xref: EMBL:AAO34693.1 xref: EMBL:AAO34694.1 xref: EMBL:AAO34695.1 xref: EMBL:AAO34696.1 xref: EMBL:AAO34697.1 xref: EMBL:AAO34698.1 xref: EMBL:AAO34699.1 xref: EMBL:AAO34700.1 xref: EMBL:AAO88210.1 xref: EMBL:BAA88847.1 xref: EMBL:BAA95552.1 xref: UniProtKB:O75490 xref: UniProtKB:O75491 xref: UniProtKB:O76083 xref: UniProtKB:O95225 xref: UniProtKB:Q86SF7 xref: UniProtKB:Q86SI6 xref: UniProtKB:Q86SJ3 xref: UniProtKB:Q86WN3 xref: UniProtKB:Q86WN4 xref: UniProtKB:Q86WN5 xref: UniProtKB:Q86WN6 xref: UniProtKB:Q86WN7 xref: UniProtKB:Q86WN8 xref: UniProtKB:Q86WN9 xref: UniProtKB:Q86WP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019348 ! PDE9A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006858 ! 3',5'-cyclic-GMP phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015046 ! pde9a-trim32 physical interaction relationship: participates_in CCO:I0015453 ! pde9a-phyhipl physical interaction relationship: participates_in CCO:I0015774 ! pde9a-pde9a physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069186 ! PDE9A_HUMAN-Phosphotyrosine29 [Term] id: CCO:B0054694 name: OR7C1_HUMAN def: "Olfactory receptor 7C1" [UniProtKB:O76099] synonym: "Olfactory receptor TPCR86" EXACT [UniProtKB:O76099] xref: EMBL:AAC25625.1 xref: EMBL:AAK95031.1 xref: EMBL:CAA61823.1 xref: UniProtKB:O76099 xref: UniProtKB:Q15621 xref: UniProtKB:Q96R94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019217 ! OR7C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054695 name: OR7AA_HUMAN def: "Olfactory receptor 7A10" [UniProtKB:O76100] synonym: "Olfactory receptor OR19-18" EXACT [UniProtKB:O76100] synonym: "OST027" EXACT [UniProtKB:O76100] xref: EMBL:AAC25627.1 xref: EMBL:AAK95027.1 xref: EMBL:DAA04620.1 xref: UniProtKB:O76100 xref: UniProtKB:Q6IFP0 xref: UniProtKB:Q96R97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019215 ! OR7A10_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054696 name: DDAH1_HUMAN def: "N(G),N(G)-dimethylarginine dimethylaminohydrolase 1" [UniProtKB:O94760] synonym: "DDAH-1" EXACT [UniProtKB:O94760] synonym: "DDAHI" EXACT [UniProtKB:O94760] synonym: "Dimethylargininase-1" EXACT [UniProtKB:O94760] synonym: "Dimethylarginine dimethylaminohydrolase 1" EXACT [UniProtKB:O94760] synonym: "EC 3.5.3.18" EXACT [UniProtKB:O94760] xref: EMBL:AAH33680.1 xref: EMBL:AAH43235.2 xref: EMBL:BAA37117.1 xref: UniProtKB:O94760 xref: UniProtKB:Q86XK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017537 ! DDAH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: transforms_into CCO:B0064684 ! DDAH1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0054697 name: RMP_HUMAN def: "Unconventional prefoldin RPB5 interactor" [UniProtKB:O94763] synonym: "Protein NNX3" EXACT [UniProtKB:O94763] synonym: "RNA polymerase II subunit 5-mediating protein" EXACT [UniProtKB:O94763] synonym: "RPB5-mediating protein" EXACT [UniProtKB:O94763] xref: EMBL:AAD08679.1 xref: EMBL:BAA34781.1 xref: EMBL:BAF84859.1 xref: UniProtKB:A8K805 xref: UniProtKB:O94763 xref: UniProtKB:Q9UNU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019755 ! RMP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016705 ! map3k3-rmp physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070095 ! RMP_HUMAN-Phosphothreonine241 relationship: transforms_into CCO:B0070096 ! RMP_HUMAN-Phosphothreonine242 relationship: transforms_into CCO:B0070097 ! RMP_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0070098 ! RMP_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0070099 ! RMP_HUMAN-Phosphoserine439 [Term] id: CCO:B0054698 name: MTA2_HUMAN def: "Metastasis-associated protein MTA2" [UniProtKB:O94776] synonym: "Metastasis-associated 1-like 1" EXACT [UniProtKB:O94776] synonym: "MTA1-L1 protein" EXACT [UniProtKB:O94776] synonym: "p53 target protein in deacetylase complex" EXACT [UniProtKB:O94776] xref: EMBL:AAG02241.1 xref: EMBL:AAH23656.1 xref: EMBL:AAH53650.1 xref: EMBL:BAA36562.1 xref: EMBL:BAA36707.1 xref: UniProtKB:O94776 xref: UniProtKB:Q9UQB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018671 ! MTA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068312 ! MTA2_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0068313 ! MTA2_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0068314 ! MTA2_HUMAN-Phosphothreonine540 [Term] id: CCO:B0054699 name: KPCD3_HUMAN def: "Serine/threonine-protein kinase D3" [UniProtKB:O94806] synonym: "EC 2.7.11.13" EXACT [UniProtKB:O94806] synonym: "nPKC-nu" EXACT [UniProtKB:O94806] synonym: "Protein kinase C nu type" EXACT [UniProtKB:O94806] synonym: "Protein kinase EPK2" EXACT [UniProtKB:O94806] xref: EMBL:AAH30706.1 xref: EMBL:BAA36514.1 xref: UniProtKB:O94806 xref: UniProtKB:Q8NEL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018434 ! PRKD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0067408 ! KPCD3_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0067409 ! KPCD3_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0067410 ! KPCD3_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0067411 ! KPCD3_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0067412 ! KPCD3_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0067413 ! KPCD3_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0067414 ! KPCD3_HUMAN-Phosphoserine735 [Term] id: CCO:B0054700 name: RGS11_HUMAN def: "Regulator of G-protein signaling 11" [UniProtKB:O94810] synonym: "RGS11" EXACT [UniProtKB:O94810] xref: EMBL:AAC69175.1 xref: EMBL:AAC69176.1 xref: EMBL:AAK61221.1 xref: EMBL:BAA74751.1 xref: EMBL:CAI95582.1 xref: UniProtKB:O75883 xref: UniProtKB:O94810 xref: UniProtKB:Q4TT71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019702 ! RGS11_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0054701 name: TPPP_HUMAN def: "Tubulin polymerization-promoting protein" [UniProtKB:O94811] synonym: "25 kDa brain-specific protein" EXACT [UniProtKB:O94811] synonym: "p24" EXACT [UniProtKB:O94811] synonym: "p25" EXACT [UniProtKB:O94811] synonym: "p25-alpha" EXACT [UniProtKB:O94811] synonym: "TPPP" EXACT [UniProtKB:O94811] xref: EMBL:AAH40496.1 xref: EMBL:AAV38838.1 xref: EMBL:BAA36164.1 xref: UniProtKB:O94811 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020332 ! TPPP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0001414 ! positive regulation of protein complex assembly relationship: participates_in CCO:P0001577 ! positive regulation of protein polymerization relationship: transforms_into CCO:B0071484 ! TPPP_HUMAN-Phosphothreonine14 relationship: transforms_into CCO:B0071485 ! TPPP_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0071486 ! TPPP_HUMAN-Phosphoserine32 [Term] id: CCO:B0054702 name: PKHG5_HUMAN def: "Pleckstrin homology domain-containing family G member 5" [UniProtKB:O94827] synonym: "GEF720" EXACT [UniProtKB:O94827] synonym: "Guanine nucleotide exchange factor 720" EXACT [UniProtKB:O94827] xref: EMBL:AAH15231.1 xref: EMBL:AAH42606.1 xref: EMBL:BAA34440.2 xref: EMBL:BAC77354.1 xref: EMBL:BAC85124.1 xref: EMBL:CAI16069.1 xref: EMBL:CAI22159.1 xref: EMBL:CAI22161.1 xref: EMBL:CAI22162.1 xref: EMBL:CAI22164.1 xref: EMBL:CAI22165.1 xref: EMBL:EAW71539.1 xref: EMBL:EAW71547.1 xref: UniProtKB:O94827 xref: UniProtKB:Q5SY17 xref: UniProtKB:Q5T8W5 xref: UniProtKB:Q5T8W9 xref: UniProtKB:Q6ZNM0 xref: UniProtKB:Q7Z436 xref: UniProtKB:Q86YD8 xref: UniProtKB:Q96BS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019417 ! PLEKHG5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0069355 ! PKHG5_HUMAN-Phosphoserine932 relationship: transforms_into CCO:B0069356 ! PKHG5_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0069357 ! PKHG5_HUMAN-Phosphoserine959 [Term] id: CCO:B0054703 name: TOX4_HUMAN def: "TOX high mobility group box family member 4" [UniProtKB:O94842] synonym: "Epidermal Langerhans cell protein LCP1" EXACT [UniProtKB:O94842] xref: EMBL:AAH13689.1 xref: EMBL:BAA34457.2 xref: UniProtKB:O94842 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020327 ! TOX4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019022 ! atxn1-c14orf92 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071456 ! TOX4_HUMAN-Phosphoserine182 [Term] id: CCO:B0054704 name: RHBT1_HUMAN def: "Rho-related BTB domain-containing protein 1" [UniProtKB:O94844] xref: EMBL:AAH32848.1 xref: EMBL:AAH41791.1 xref: EMBL:BAA34460.2 xref: EMBL:BAC11421.1 xref: UniProtKB:O94844 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019710 ! RHOBTB1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069925 ! RHBT1_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0069926 ! RHBT1_HUMAN-Phosphothreonine483 [Term] id: CCO:B0054705 name: FARP2_HUMAN def: "FERM, RhoGEF and pleckstrin domain-containing protein 2" [UniProtKB:O94887] synonym: "FERM domain including RhoGEF" EXACT [UniProtKB:O94887] synonym: "FIR" EXACT [UniProtKB:O94887] xref: EMBL:AAH21301.1 xref: EMBL:AAY14682.1 xref: EMBL:BAA34513.2 xref: EMBL:CAB59185.1 xref: UniProtKB:O94887 xref: UniProtKB:Q53QM5 xref: UniProtKB:Q8WU27 xref: UniProtKB:Q9UFE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017764 ! FARP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001131 ! Rac protein signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0066131 ! FARP2_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0066132 ! FARP2_HUMAN-Phosphoserine876 relationship: transforms_into CCO:B0066133 ! FARP2_HUMAN-Phosphoserine881 [Term] id: CCO:B0054706 name: ZN432_HUMAN def: "Zinc finger protein 432" [UniProtKB:O94892] xref: EMBL:AAH02858.1 xref: EMBL:BAA34518.2 xref: UniProtKB:O94892 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020746 ! ZNF432_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072125 ! ZN432_HUMAN-Nitrated tyrosine41 [Term] id: CCO:B0054707 name: TOX_HUMAN def: "Thymocyte selection-associated high mobility group box protein TOX" [UniProtKB:O94900] synonym: "Thymus high mobility group box protein TOX" EXACT [UniProtKB:O94900] xref: EMBL:AAH16665.1 xref: EMBL:BAA34528.2 xref: UniProtKB:O94900 xref: UniProtKB:Q96AV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020328 ! TOX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054708 name: PRP6_HUMAN def: "Pre-mRNA-processing factor 6" [UniProtKB:O94906] synonym: "PRP6 homolog" EXACT [UniProtKB:O94906] synonym: "U5 snRNP-associated 102 kDa protein" EXACT [UniProtKB:O94906] synonym: "U5-102 kDa protein" EXACT [UniProtKB:O94906] xref: EMBL:AAD01798.1 xref: EMBL:AAF66128.1 xref: EMBL:AAH01666.1 xref: EMBL:BAA37140.1 xref: EMBL:CAB70695.1 xref: EMBL:CAC16610.2 xref: EMBL:CAH71582.1 xref: EMBL:CAI21906.1 xref: UniProtKB:O94906 xref: UniProtKB:O95109 xref: UniProtKB:Q5VXS5 xref: UniProtKB:Q9H3Z1 xref: UniProtKB:Q9H4T9 xref: UniProtKB:Q9H4U8 xref: UniProtKB:Q9NTE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019520 ! PRPF6_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0018048 ! araf-c20orf14-1 physical interaction relationship: participates_in CCO:I0018721 ! smarca2-c20orf14 physical interaction relationship: participates_in CCO:I0018801 ! araf-c20orf14 physical interaction relationship: participates_in CCO:I0018804 ! araf-c20orf14-2 physical interaction relationship: participates_in CCO:I0018816 ! araf-c20orf14-3 physical interaction relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054709 name: DKK1_HUMAN def: "Dickkopf-related protein 1 precursor" [UniProtKB:O94907] synonym: "Dickkopf-1" EXACT [UniProtKB:O94907] synonym: "Dkk-1" EXACT [UniProtKB:O94907] synonym: "hDkk-1" EXACT [UniProtKB:O94907] synonym: "SK" EXACT [UniProtKB:O94907] xref: EMBL:AAD21087.1 xref: EMBL:AAF02674.1 xref: EMBL:AAG15544.1 xref: EMBL:AAH01539.1 xref: EMBL:AAQ89364.1 xref: EMBL:BAA34651.1 xref: UniProtKB:O94907 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017579 ! DKK1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0015048 ! dkk1-mdfi physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0054710 name: LPHN1_HUMAN def: "Latrophilin-1 precursor" [UniProtKB:O94910] synonym: "Calcium-independent alpha-latrotoxin receptor 1" EXACT [UniProtKB:O94910] synonym: "Lectomedin-2" EXACT [UniProtKB:O94910] xref: EMBL:AAG27461.1 xref: EMBL:AAH02974.1 xref: EMBL:AAH07587.1 xref: EMBL:BAA74844.2 xref: EMBL:BAC06134.1 xref: UniProtKB:O94910 xref: UniProtKB:Q96IE7 xref: UniProtKB:Q9BU07 xref: UniProtKB:Q9HAR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018516 ! LPHN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0067765 ! LPHN1_HUMAN-Phosphoserine1377 relationship: transforms_into CCO:B0067766 ! LPHN1_HUMAN-Phosphotyrosine1440 [Term] id: CCO:B0054711 name: FRYL_HUMAN def: "Protein furry homolog-like" [UniProtKB:O94915] synonym: "ALL1-fused gene from chromosome 4p12" EXACT [UniProtKB:O94915] xref: EMBL:AAD00351.1 xref: EMBL:AAH21803.1 xref: EMBL:BAA74849.1 xref: EMBL:CAB70804.1 xref: UniProtKB:O94915 xref: UniProtKB:O95640 xref: UniProtKB:Q8WTZ5 xref: UniProtKB:Q9NT40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017836 ! FRYL_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017435 ! disc1-kiaa0826 physical interaction relationship: participates_in CCO:I0017436 ! disc1-kiaa0826-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066282 ! FRYL_HUMAN-Phosphoserine2272 [Term] id: CCO:B0054712 name: NFAT5_HUMAN def: "Nuclear factor of activated T-cells 5" [UniProtKB:O94916] synonym: "NF-AT5" EXACT [UniProtKB:O94916] synonym: "T-cell transcription factor NFAT5" EXACT [UniProtKB:O94916] synonym: "TonE-binding protein" EXACT [UniProtKB:O94916] synonym: "TonEBP" EXACT [UniProtKB:O94916] synonym: "Tonicity-responsive enhancer-binding protein" EXACT [UniProtKB:O94916] xref: EMBL:AAD18136.1 xref: EMBL:AAD38360.1 xref: EMBL:AAD48441.1 xref: EMBL:BAA74850.2 xref: EMBL:CAB09693.1 xref: UniProtKB:O94916 xref: UniProtKB:O95693 xref: UniProtKB:Q9UN18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018770 ! NFAT5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054713 name: JHD3B_HUMAN def: "JmjC domain-containing histone demethylation protein 3B" [UniProtKB:O94953] synonym: "EC 1.14.11.-" EXACT [UniProtKB:O94953] synonym: "Jumonji domain-containing protein 2B" EXACT [UniProtKB:O94953] xref: EMBL:AAC33799.1 xref: EMBL:AAF31271.1 xref: EMBL:AAH63889.1 xref: EMBL:BAA74899.2 xref: EMBL:CAB63748.2 xref: UniProtKB:O75274 xref: UniProtKB:O94953 xref: UniProtKB:Q6P3R5 xref: UniProtKB:Q9P1V1 xref: UniProtKB:Q9UF40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018363 ! JMJD2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020592 ! mgc5309-jmjd2b physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067216 ! JHD3B_HUMAN-Phosphothreonine305 relationship: transforms_into CCO:B0067217 ! JHD3B_HUMAN-Phosphoserine566 relationship: transforms_into CCO:B0067218 ! JHD3B_HUMAN-Phosphoserine622 [Term] id: CCO:B0054714 name: CMTA2_HUMAN def: "Calmodulin-binding transcription activator 2" [UniProtKB:O94983] xref: EMBL:AAH10050.2 xref: EMBL:AAH16163.1 xref: EMBL:BAA74932.1 xref: EMBL:CAD38553.1 xref: EMBL:CAD38818.2 xref: UniProtKB:O94983 xref: UniProtKB:Q7Z6M8 xref: UniProtKB:Q8N3V0 xref: UniProtKB:Q8NDG4 xref: UniProtKB:Q96G17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017396 ! CAMTA2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018547 ! nkx2_5-camta2 colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054715 name: OR2F2_HUMAN def: "Olfactory receptor 2F2" [UniProtKB:O95006] synonym: "Olfactory receptor 7-1" EXACT [UniProtKB:O95006] synonym: "Olfactory receptor OR7-6" EXACT [UniProtKB:O95006] synonym: "OR7-1" EXACT [UniProtKB:O95006] xref: EMBL:DAA04612.1 xref: UniProtKB:O95006 xref: UniProtKB:Q6IFP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019093 ! OR2F2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054716 name: O4F21_HUMAN def: "Olfactory receptor 4F21" [UniProtKB:O95013] xref: EMBL:AAD05195.1 xref: UniProtKB:A6NIU1 xref: UniProtKB:O95013 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018979 ! OR4F21_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054717 name: OR2A4_HUMAN def: "Olfactory receptor 2A4" [UniProtKB:O95047] synonym: "Olfactory receptor OR6-37" EXACT [UniProtKB:O95047] xref: EMBL:AAD05193.1 xref: EMBL:AAI20954.1 xref: EMBL:AAI20955.1 xref: EMBL:CAB99212.1 xref: EMBL:DAA04842.1 xref: UniProtKB:O95047 xref: UniProtKB:Q0VAR3 xref: UniProtKB:Q6IF18 xref: UniProtKB:Q9NQN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019081 ! OR2A4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054718 name: KCNK2_HUMAN def: "Potassium channel subfamily K member 2" [UniProtKB:O95069] synonym: "Outward rectifying potassium channel protein TREK-1" EXACT [UniProtKB:O95069] synonym: "TREK-1 K(+) channel subunit" EXACT [UniProtKB:O95069] synonym: "Two pore domain potassium channel TREK-1" EXACT [UniProtKB:O95069] synonym: "Two pore potassium channel TPKC1" EXACT [UniProtKB:O95069] xref: EMBL:AAD01203.1 xref: EMBL:AAD47569.1 xref: EMBL:AAF89743.1 xref: EMBL:AAH69462.1 xref: EMBL:AAI01694.1 xref: EMBL:AAI01696.1 xref: EMBL:AAT49015.1 xref: EMBL:ABM47413.1 xref: EMBL:ABM47414.1 xref: UniProtKB:A1Z1V3 xref: UniProtKB:O95069 xref: UniProtKB:Q5DP48 xref: UniProtKB:Q9NRT2 xref: UniProtKB:Q9UNE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018398 ! KCNK2_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0002728 ! outward rectifier potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054719 name: UBR5_HUMAN def: "E3 ubiquitin-protein ligase UBR5" [UniProtKB:O95071] synonym: "E3 ubiquitin-protein ligase, HECT domain-containing 1" EXACT [UniProtKB:O95071] synonym: "EC 6.3.2.-" EXACT [UniProtKB:O95071] synonym: "hHYD" EXACT [UniProtKB:O95071] synonym: "Hyperplastic discs protein homolog" EXACT [UniProtKB:O95071] synonym: "Progestin-induced protein" EXACT [UniProtKB:O95071] xref: EMBL:AAD01259.2 xref: EMBL:AAF88143.1 xref: EMBL:BAA74919.3 xref: UniProtKB:O94970 xref: UniProtKB:O95071 xref: UniProtKB:Q9NPL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020402 ! UBR5_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002965 ! progesterone receptor signaling pathway relationship: transforms_into CCO:B0071703 ! UBR5_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0071704 ! UBR5_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0071705 ! UBR5_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0071706 ! UBR5_HUMAN-Phosphoserine1549 relationship: transforms_into CCO:B0071707 ! UBR5_HUMAN-Phosphotyrosine1746 relationship: transforms_into CCO:B0071708 ! UBR5_HUMAN-Phosphoserine2071 [Term] id: CCO:B0054720 name: FSBP_HUMAN def: "Fibrinogen silencer-binding protein" [UniProtKB:O95073] xref: EMBL:AAD09313.1 xref: EMBL:AAH33710.2 xref: EMBL:AAL96666.1 xref: UniProtKB:O95073 xref: UniProtKB:Q8N4S5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017838 ! FSBP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002978 ! DNA translocase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054721 name: ALX3_HUMAN def: "Homeobox protein aristaless-like 3" [UniProtKB:O95076] synonym: "Proline-rich transcription factor ALX3" EXACT [UniProtKB:O95076] xref: EMBL:AAD01417.2 xref: EMBL:AAD01418.1 xref: EMBL:AAI12008.1 xref: EMBL:AAI13429.1 xref: EMBL:CAI22714.1 xref: EMBL:EAW56430.1 xref: UniProtKB:O95075 xref: UniProtKB:O95076 xref: UniProtKB:Q5T8M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016955 ! ALX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054722 name: HRBL_HUMAN def: "HIV-1 Rev-binding protein-like protein" [UniProtKB:O95081] synonym: "RAB-R" EXACT [UniProtKB:O95081] synonym: "Rev/Rex activation domain-binding protein related" EXACT [UniProtKB:O95081] xref: EMBL:AAC78803.1 xref: EMBL:AAD01550.1 xref: EMBL:AAH09393.1 xref: EMBL:AAH17329.1 xref: UniProtKB:O75429 xref: UniProtKB:O95081 xref: UniProtKB:Q96AB9 xref: UniProtKB:Q96GL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018158 ! HRBL_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0054723 name: NKX22_HUMAN def: "Homeobox protein Nkx-2.2" [UniProtKB:O95096] synonym: "Homeobox protein NK-2 homolog B" EXACT [UniProtKB:O95096] xref: EMBL:AAC83132.1 xref: EMBL:AAH75092.1 xref: EMBL:AAH75093.1 xref: EMBL:CAC00770.1 xref: UniProtKB:O95096 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018795 ! NKX2-2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054724 name: O95098_HUMAN def: "G protein-coupled receptor kinase 1b" [UniProtKB:O95098] xref: EMBL:AAC97160.1 xref: UniProtKB:O95098 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019748 ! GRK1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001680 ! G-protein coupled photoreceptor activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001113 ! regulation of membrane potential in photoreceptor cell relationship: participates_in CCO:P0001114 ! maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling [Term] id: CCO:B0054725 name: ZN202_HUMAN def: "Zinc finger protein 202" [UniProtKB:O95125] synonym: "Zinc finger protein with KRAB and SCAN domains 10" EXACT [UniProtKB:O95125] xref: EMBL:AAC79940.1 xref: EMBL:AAC79941.1 xref: EMBL:AAH13382.1 xref: EMBL:AAY88738.1 xref: EMBL:CAB82384.1 xref: EMBL:CAC21447.1 xref: UniProtKB:O95125 xref: UniProtKB:Q4JG21 xref: UniProtKB:Q9H1B9 xref: UniProtKB:Q9NSM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020651 ! ZNF202_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015803 ! znf202-znf473 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054726 name: O95133_HUMAN def: "SOX-29 protein" [UniProtKB:O95133] xref: EMBL:AAC94974.1 xref: UniProtKB:O95133 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021075 ! SOX5P_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054727 name: S1PR2_HUMAN def: "Sphingosine 1-phosphate receptor 2" [UniProtKB:O95136] synonym: "Endothelial differentiation G-protein coupled receptor 5" EXACT [UniProtKB:O95136] synonym: "S1P receptor 2" EXACT [UniProtKB:O95136] synonym: "S1P receptor Edg-5" EXACT [UniProtKB:O95136] synonym: "S1P2" EXACT [UniProtKB:O95136] synonym: "Sphingosine 1-phosphate receptor Edg-5" EXACT [UniProtKB:O95136] xref: EMBL:AAC98919.1 xref: EMBL:AAH69598.1 xref: EMBL:AAP20652.1 xref: UniProtKB:O95136 xref: UniProtKB:Q86UN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022625 ! S1PR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0054728 name: NXPH2_HUMAN def: "Neurexophilin-2 precursor" [UniProtKB:O95156] xref: EMBL:AAD02280.1 xref: EMBL:AAI01463.1 xref: EMBL:AAI01464.1 xref: EMBL:AAI04742.1 xref: EMBL:BAD11132.1 xref: UniProtKB:O95156 xref: UniProtKB:Q494R1 xref: UniProtKB:Q75QC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018894 ! NXPH2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054729 name: NXPH3_HUMAN def: "Neurexophilin-3 precursor" [UniProtKB:O95157] xref: EMBL:AAD02281.1 xref: EMBL:AAH22541.1 xref: EMBL:AAQ88890.1 xref: EMBL:BAA86473.1 xref: UniProtKB:O95157 xref: UniProtKB:Q8TBF6 xref: UniProtKB:Q9ULR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018895 ! NXPH3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054730 name: NXPH4_HUMAN def: "Neurexophilin-4 precursor" [UniProtKB:O95158] xref: EMBL:AAD02282.1 xref: EMBL:AAH36679.1 xref: EMBL:AAH53581.1 xref: EMBL:AAQ88977.1 xref: UniProtKB:O95158 xref: UniProtKB:Q7Z6L3 xref: UniProtKB:Q8N462 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018896 ! NXPH4_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054731 name: ZFPL1_HUMAN def: "Zinc finger protein-like 1" [UniProtKB:O95159] synonym: "Zinc finger protein MCG4" EXACT [UniProtKB:O95159] xref: EMBL:AAB86533.1 xref: EMBL:AAD08644.1 xref: EMBL:AAF21634.1 xref: EMBL:AAH12530.1 xref: EMBL:AAH12814.1 xref: EMBL:BAF84653.1 xref: EMBL:EAW74344.1 xref: UniProtKB:A8K7E9 xref: UniProtKB:O14616 xref: UniProtKB:O95159 xref: UniProtKB:Q9UID0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020597 ! ZFPL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020253 ! atp5j2-zfpl1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054732 name: O95165_HUMAN def: "Putative DNA polymerase" [UniProtKB:O95165] xref: EMBL:AAD02338.1 xref: UniProtKB:O95165 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0054733 name: UNC5C_HUMAN def: "Netrin receptor UNC5C precursor" [UniProtKB:O95185] synonym: "Protein unc-5 homolog C" EXACT [UniProtKB:O95185] synonym: "Unc-5 homolog 3" EXACT [UniProtKB:O95185] xref: EMBL:AAC67491.1 xref: EMBL:AAH41156.1 xref: UniProtKB:O95185 xref: UniProtKB:Q8IUT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020414 ! UNC5C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: transforms_into CCO:B0071734 ! UNC5C_HUMAN-Phosphotyrosine568 [Term] id: CCO:B0054734 name: CSPG5_HUMAN def: "Chondroitin sulfate proteoglycan 5 precursor" [UniProtKB:O95196] synonym: "Acidic leucine-rich EGF-like domain-containing brain protein" EXACT [UniProtKB:O95196] synonym: "Neuroglycan C" EXACT [UniProtKB:O95196] xref: EMBL:AAC69612.1 xref: EMBL:AAQ04774.1 xref: EMBL:AAQ04775.1 xref: EMBL:AAQ04776.1 xref: UniProtKB:O95196 xref: UniProtKB:Q71M39 xref: UniProtKB:Q71M40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017482 ! CSPG5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001025 ! Golgi-associated vesicle membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0054735 name: ZN205_HUMAN def: "Zinc finger protein 205" [UniProtKB:O95201] synonym: "Zinc finger protein 210" EXACT [UniProtKB:O95201] xref: EMBL:AAC70007.1 xref: EMBL:AAH02810.1 xref: EMBL:EAW85396.1 xref: UniProtKB:A8MZK0 xref: UniProtKB:O95201 xref: UniProtKB:Q9BU95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020652 ! ZNF205_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016158 ! ubqln4-znf205 physical interaction relationship: participates_in CCO:I0017542 ! znf205-ubqln4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054736 name: OR5F1_HUMAN def: "Olfactory receptor 5F1" [UniProtKB:O95221] synonym: "Olfactory receptor 11-10" EXACT [UniProtKB:O95221] synonym: "Olfactory receptor OR11-167" EXACT [UniProtKB:O95221] synonym: "OR11-10" EXACT [UniProtKB:O95221] xref: EMBL:AAC70017.1 xref: EMBL:AAK95012.1 xref: EMBL:DAA04741.1 xref: UniProtKB:O95221 xref: UniProtKB:Q6IFB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019185 ! OR5F1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054737 name: OR6A2_HUMAN def: "Olfactory receptor 6A2" [UniProtKB:O95222] synonym: "hP2 olfactory receptor" EXACT [UniProtKB:O95222] synonym: "Olfactory receptor 11-55" EXACT [UniProtKB:O95222] synonym: "Olfactory receptor OR11-83" EXACT [UniProtKB:O95222] synonym: "OR11-55" EXACT [UniProtKB:O95222] xref: EMBL:AAC70018.1 xref: EMBL:AAG45208.1 xref: EMBL:AAI01490.1 xref: EMBL:AAI01492.1 xref: EMBL:BAC06041.1 xref: EMBL:DAA04825.1 xref: UniProtKB:O95222 xref: UniProtKB:Q3MJC7 xref: UniProtKB:Q6IF35 xref: UniProtKB:Q9H206 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019195 ! OR6A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054738 name: VENTX_HUMAN def: "Homeobox protein VENTX" [UniProtKB:O95231] synonym: "VENT homeobox homolog" EXACT [UniProtKB:O95231] synonym: "VENT-like homeobox protein 2" EXACT [UniProtKB:O95231] xref: EMBL:AAC82375.1 xref: EMBL:AAI08916.1 xref: EMBL:AAI08917.1 xref: EMBL:AAK83043.1 xref: EMBL:CAI17343.1 xref: UniProtKB:O95231 xref: UniProtKB:Q32MZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020441 ! VENTX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054739 name: SPDEF_HUMAN def: "SAM pointed domain-containing Ets transcription factor" [UniProtKB:O95238] synonym: "Prostate epithelium-specific Ets transcription factor" EXACT [UniProtKB:O95238] synonym: "Prostate-derived Ets factor" EXACT [UniProtKB:O95238] synonym: "Prostate-specific Ets" EXACT [UniProtKB:O95238] xref: EMBL:AAC95296.1 xref: EMBL:AAH21299.1 xref: EMBL:BAA89543.1 xref: EMBL:CAH73099.1 xref: EMBL:CAH73104.1 xref: EMBL:CAI23605.1 xref: UniProtKB:O95238 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020010 ! SPDEF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054740 name: I18RA_HUMAN def: "Interleukin-18 receptor accessory protein precursor" [UniProtKB:O95256] synonym: "Accessory protein-like" EXACT [UniProtKB:O95256] synonym: "AcPL" EXACT [UniProtKB:O95256] synonym: "CD218 antigen-like family member B" EXACT [UniProtKB:O95256] synonym: "CD218b antigen" EXACT [UniProtKB:O95256] synonym: "CDw218b" EXACT [UniProtKB:O95256] synonym: "IL-18 receptor accessory protein" EXACT [UniProtKB:O95256] synonym: "IL-18RAcP" EXACT [UniProtKB:O95256] synonym: "IL-18Rbeta" EXACT [UniProtKB:O95256] synonym: "IL-1R accessory protein-like" EXACT [UniProtKB:O95256] synonym: "IL-1R7" EXACT [UniProtKB:O95256] synonym: "IL-1RAcPL" EXACT [UniProtKB:O95256] synonym: "Interleukin-18 receptor accessory protein-like" EXACT [UniProtKB:O95256] xref: EMBL:AAC72196.1 xref: EMBL:AAH69630.1 xref: EMBL:AAI06766.1 xref: EMBL:AAY15049.1 xref: EMBL:AAY15080.1 xref: UniProtKB:O95256 xref: UniProtKB:Q3KPE7 xref: UniProtKB:Q53TT4 xref: UniProtKB:Q53TU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018199 ! IL18RAP_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0066967 ! I18RA_HUMAN-Phosphothreonine401 [Term] id: CCO:B0054741 name: KCNH1_HUMAN def: "Potassium voltage-gated channel subfamily H member 1" [UniProtKB:O95259] synonym: "Ether-a-go-go potassium channel 1" EXACT [UniProtKB:O95259] synonym: "h-eag" EXACT [UniProtKB:O95259] synonym: "hEAG1" EXACT [UniProtKB:O95259] synonym: "Voltage-gated potassium channel subunit Kv10.1" EXACT [UniProtKB:O95259] xref: EMBL:AAC68668.1 xref: EMBL:AAC68669.1 xref: EMBL:CAA04700.1 xref: UniProtKB:O76035 xref: UniProtKB:O95259 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018390 ! KCNH1_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001519 ! delayed rectifier potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054742 name: PDE8B_HUMAN def: "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B" [UniProtKB:O95263] synonym: "EC 3.1.4.17" EXACT [UniProtKB:O95263] synonym: "HSPDE8B" EXACT [UniProtKB:O95263] xref: EMBL:AAC69564.2 xref: EMBL:AAN71723.1 xref: EMBL:AAN71724.1 xref: EMBL:AAN71725.1 xref: EMBL:AAN71726.1 xref: EMBL:AAN71727.1 xref: EMBL:BAC53762.1 xref: EMBL:BAC53763.1 xref: EMBL:BAC53764.1 xref: EMBL:BAC53765.1 xref: EMBL:CAD38584.1 xref: UniProtKB:O95263 xref: UniProtKB:Q86XK8 xref: UniProtKB:Q8IUJ7 xref: UniProtKB:Q8IUJ8 xref: UniProtKB:Q8IUJ9 xref: UniProtKB:Q8IUK0 xref: UniProtKB:Q8N3T2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019347 ! PDE8B_human relationship: has_function CCO:F0000030 ! two-component response regulator activity relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054743 name: GRP1_HUMAN def: "RAS guanyl-releasing protein 1" [UniProtKB:O95267] synonym: "Calcium and DAG-regulated guanine nucleotide exchange factor II" EXACT [UniProtKB:O95267] synonym: "CalDAG-GEFII" EXACT [UniProtKB:O95267] synonym: "Ras guanyl-releasing protein" EXACT [UniProtKB:O95267] xref: EMBL:AAC79699.1 xref: EMBL:AAC97349.1 xref: EMBL:AAF21898.1 xref: EMBL:AAH67298.1 xref: EMBL:AAI09297.1 xref: EMBL:AAI09298.1 xref: EMBL:AAT47482.2 xref: EMBL:AAW32406.2 xref: EMBL:AAX54699.4 xref: EMBL:AAX76907.1 xref: EMBL:BAD92085.1 xref: UniProtKB:O95267 xref: UniProtKB:Q56CZ0 xref: UniProtKB:Q58G75 xref: UniProtKB:Q59HB1 xref: UniProtKB:Q5I3A8 xref: UniProtKB:Q6GV31 xref: UniProtKB:Q6NX39 xref: UniProtKB:Q7LDG6 xref: UniProtKB:Q9UI94 xref: UniProtKB:Q9UNN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018075 ! RASGRP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 [Term] id: CCO:B0054744 name: O95268_HUMAN def: "Origin recognition complex subunit ORC5T" [UniProtKB:O95268] xref: EMBL:AAC64401.1 xref: UniProtKB:O95268 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005236 ! ORC5L_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000269 ! nuclear origin of replication recognition complex relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0054745 name: TNKS1_HUMAN def: "Tankyrase-1" [UniProtKB:O95271] synonym: "EC 2.4.2.30" EXACT [UniProtKB:O95271] synonym: "TANK1" EXACT [UniProtKB:O95271] synonym: "Tankyrase I" EXACT [UniProtKB:O95271] synonym: "TNKS-1" EXACT [UniProtKB:O95271] synonym: "TRF1-interacting ankyrin-related ADP-ribose polymerase" EXACT [UniProtKB:O95271] xref: EMBL:AAC79841.1 xref: EMBL:AAC79842.1 xref: EMBL:AAC79843.1 xref: EMBL:AAC79844.1 xref: UniProtKB:O95271 xref: UniProtKB:O95272 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020307 ! TNKS_human relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0017466 ! disc1-tnks physical interaction relationship: participates_in CCO:I0017467 ! sh3bp5-tnks physical interaction relationship: participates_in CCO:I0018260 ! fnbp1-tnks-1 physical interaction relationship: participates_in CCO:I0018261 ! fnbp1-tnks-4 colocalization relationship: participates_in CCO:I0018756 ! fnbp1-tnks-3 physical interaction relationship: participates_in CCO:I0019326 ! fnbp1-tnks-2 physical interaction relationship: participates_in CCO:P0000692 ! telomere maintenance via telomerase relationship: transforms_into CCO:B0071440 ! TNKS1_HUMAN-Phosphoserine365 [Term] id: CCO:B0054746 name: VAPB_HUMAN def: "Vesicle-associated membrane protein-associated protein B/C" [UniProtKB:O95292] synonym: "VAMP-associated protein B/C" EXACT [UniProtKB:O95292] synonym: "VAMP-B/VAMP-C" EXACT [UniProtKB:O95292] synonym: "VAP-B/VAP-C" EXACT [UniProtKB:O95292] xref: EMBL:AAD13577.1 xref: EMBL:AAD13578.1 xref: EMBL:AAF67013.1 xref: EMBL:AAH01712.1 xref: EMBL:AAQ88829.1 xref: EMBL:CAC15021.1 xref: UniProtKB:O95292 xref: UniProtKB:O95293 xref: UniProtKB:Q9P0H0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020433 ! VAPB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: transforms_into CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 relationship: transforms_into CCO:B0071775 ! VAPB_HUMAN-Phosphoserine160 relationship: transforms_into CCO:B0071776 ! VAPB_HUMAN-Phosphoserine206 [Term] id: CCO:B0054747 name: RASL1_HUMAN def: "RasGAP-activating-like protein 1" [UniProtKB:O95294] xref: EMBL:AAD09006.1 xref: EMBL:AAH14420.1 xref: EMBL:AAH93724.1 xref: EMBL:CAB66607.2 xref: UniProtKB:O95294 xref: UniProtKB:Q52M03 xref: UniProtKB:Q96CC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019629 ! RASAL1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054748 name: MPZL1_HUMAN def: "Myelin protein zero-like protein 1 precursor" [UniProtKB:O95297] synonym: "Protein zero-related" EXACT [UniProtKB:O95297] xref: EMBL:AAC72231.1 xref: EMBL:AAD55346.1 xref: EMBL:AAD55347.1 xref: EMBL:AAF00083.1 xref: EMBL:AAF00084.1 xref: EMBL:AAF63499.1 xref: EMBL:AAH07881.1 xref: EMBL:AAO14645.1 xref: EMBL:AAO14646.1 xref: EMBL:AAO14647.1 xref: EMBL:AAQ89378.1 xref: EMBL:CAC36033.2 xref: EMBL:CAG46957.1 xref: EMBL:CAI20143.1 xref: EMBL:CAI20144.2 xref: UniProtKB:O95297 xref: UniProtKB:Q5R332 xref: UniProtKB:Q8IX11 xref: UniProtKB:Q9BWZ3 xref: UniProtKB:Q9NYK4 xref: UniProtKB:Q9UL20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018650 ! MPZL1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015977 ! mpzl1-ptpn1 physical interaction relationship: participates_in CCO:I0019458 ! mpzl1-ptpn1-2 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0068266 ! MPZL1_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0068267 ! MPZL1_HUMAN-Phosphotyrosine241 relationship: transforms_into CCO:B0068268 ! MPZL1_HUMAN-Phosphotyrosine263 [Term] id: CCO:B0054749 name: SIX3_HUMAN def: "Homeobox protein SIX3" [UniProtKB:O95343] synonym: "Sine oculis homeobox homolog 3" EXACT [UniProtKB:O95343] xref: EMBL:AAD11939.1 xref: EMBL:AAD15753.1 xref: EMBL:AAD51091.1 xref: EMBL:CAB42539.1 xref: UniProtKB:O95343 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019922 ! SIX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054750 name: ATG7_HUMAN def: "Autophagy-related protein 7" [UniProtKB:O95352] synonym: "APG7-like" EXACT [UniProtKB:O95352] synonym: "hAGP7" EXACT [UniProtKB:O95352] synonym: "Ubiquitin-activating enzyme E1-like protein" EXACT [UniProtKB:O95352] xref: EMBL:AAC69630.1 xref: EMBL:AAH00091.1 xref: EMBL:CAB59250.1 xref: UniProtKB:O95352 xref: UniProtKB:Q7L8L0 xref: UniProtKB:Q9BWP2 xref: UniProtKB:Q9UFH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017097 ! ATG7_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001197 ! ubiquitin activating enzyme activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017407 ! atg7-map1lc3b direct interaction relationship: participates_in CCO:I0017408 ! atg7-gabarap direct interaction relationship: participates_in CCO:I0017409 ! atg7-gabarapl2 direct interaction relationship: participates_in CCO:P0001435 ! positive regulation of protein modification process [Term] id: CCO:B0054751 name: ZBT7A_HUMAN def: "Zinc finger and BTB domain-containing protein 7A" [UniProtKB:O95365] synonym: "Factor binding IST protein 1" EXACT [UniProtKB:O95365] synonym: "Factor that binds to inducer of short transcripts protein 1" EXACT [UniProtKB:O95365] synonym: "FBI-1" EXACT [UniProtKB:O95365] synonym: "HIV-1 1st-binding protein 1" EXACT [UniProtKB:O95365] synonym: "Leukemia/lymphoma-related factor" EXACT [UniProtKB:O95365] synonym: "POK erythroid myeloid ontogenic factor" EXACT [UniProtKB:O95365] synonym: "Pokemon" EXACT [UniProtKB:O95365] synonym: "POZ and Krueppel erythroid myeloid ontogenic factor" EXACT [UniProtKB:O95365] synonym: "TIP21" EXACT [UniProtKB:O95365] synonym: "TTF-I-interacting peptide 21" EXACT [UniProtKB:O95365] xref: EMBL:AAB58414.1 xref: EMBL:AAC72973.1 xref: EMBL:AAH84568.1 xref: EMBL:AAI13512.1 xref: UniProtKB:O00456 xref: UniProtKB:O95365 xref: UniProtKB:Q14D41 xref: UniProtKB:Q5XG86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020564 ! ZBTB7A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071976 ! ZBT7A_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0071977 ! ZBT7A_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0071978 ! ZBT7A_HUMAN-Phosphoserine526 relationship: transforms_into CCO:B0071979 ! ZBT7A_HUMAN-Phosphoserine549 [Term] id: CCO:B0054752 name: OR2C1_HUMAN def: "Olfactory receptor 2C1" [UniProtKB:O95371] synonym: "Olfactory receptor OR16-1" EXACT [UniProtKB:O95371] synonym: "Olfactory receptor OR16-2" EXACT [UniProtKB:O95371] synonym: "OLFmf3" EXACT [UniProtKB:O95371] xref: EMBL:AAC83557.1 xref: EMBL:AAH69456.1 xref: EMBL:DAA04805.1 xref: EMBL:DAA04826.1 xref: UniProtKB:O95371 xref: UniProtKB:Q6IF34 xref: UniProtKB:Q6IF55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019089 ! OR2C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054753 name: TFIP8_HUMAN def: "Tumor necrosis factor, alpha-induced protein 8" [UniProtKB:O95379] synonym: "Head and neck tumor and metastasis-related protein" EXACT [UniProtKB:O95379] synonym: "MDC-3.13" EXACT [UniProtKB:O95379] synonym: "NDED" EXACT [UniProtKB:O95379] synonym: "NF-kappa-B-inducible DED-containing protein" EXACT [UniProtKB:O95379] synonym: "SCC-S2" EXACT [UniProtKB:O95379] synonym: "TNF-induced protein GG2-1" EXACT [UniProtKB:O95379] xref: EMBL:AAC72975.1 xref: EMBL:AAC72976.1 xref: EMBL:AAC83229.1 xref: EMBL:AAF29435.1 xref: EMBL:AAH05352.1 xref: EMBL:AAH07014.1 xref: EMBL:CAG33418.1 xref: UniProtKB:O95379 xref: UniProtKB:Q9P1Q1 xref: UniProtKB:Q9UER5 xref: UniProtKB:Q9UP47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020250 ! TNFAIP8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005787 ! caspase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015148 ! med4-tnfaip8 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0001152 ! negative regulation of anti-apoptosis [Term] id: CCO:B0054754 name: M3K6_HUMAN def: "Mitogen-activated protein kinase kinase kinase 6" [UniProtKB:O95382] synonym: "Apoptosis signal-regulating kinase 2" EXACT [UniProtKB:O95382] synonym: "EC 2.7.11.25" EXACT [UniProtKB:O95382] xref: EMBL:AAD05304.1 xref: EMBL:AAH15914.1 xref: EMBL:AAI29951.1 xref: EMBL:AAI29952.1 xref: EMBL:BAD12485.1 xref: EMBL:BAD92042.1 xref: EMBL:CAM12869.1 xref: UniProtKB:A2ACE8 xref: UniProtKB:A2VDG4 xref: UniProtKB:A2VDG5 xref: UniProtKB:O95382 xref: UniProtKB:Q59HF4 xref: UniProtKB:Q75PK3 xref: UniProtKB:Q96B75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018539 ! MAP3K6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: transforms_into CCO:B0067819 ! M3K6_HUMAN-Phosphothreonine806 [Term] id: CCO:B0054755 name: WISP3_HUMAN def: "WNT1-inducible-signaling pathway protein 3 precursor" [UniProtKB:O95389] synonym: "WISP-3" EXACT [UniProtKB:O95389] xref: EMBL:AAC96323.1 xref: EMBL:AAQ88715.1 xref: EMBL:AAQ88716.1 xref: EMBL:CAI19998.1 xref: UniProtKB:O95389 xref: UniProtKB:Q6UXH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020477 ! WISP3_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054756 name: GDF11_HUMAN def: "Growth/differentiation factor 11 precursor" [UniProtKB:O95390] synonym: "Bone morphogenetic protein 11" EXACT [UniProtKB:O95390] synonym: "GDF-11" EXACT [UniProtKB:O95390] xref: EMBL:AAC72852.1 xref: EMBL:AAF21630.1 xref: EMBL:AAF21631.1 xref: UniProtKB:O95390 xref: UniProtKB:Q9UID1 xref: UniProtKB:Q9UID2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017903 ! GDF11_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:B0054757 name: RPGF3_HUMAN def: "Rap guanine nucleotide exchange factor 3" [UniProtKB:O95398] synonym: "cAMP-GEFI" EXACT [UniProtKB:O95398] synonym: "cAMP-regulated guanine nucleotide exchange factor I" EXACT [UniProtKB:O95398] synonym: "Epac 1" EXACT [UniProtKB:O95398] synonym: "Exchange factor directly activated by cAMP 1" EXACT [UniProtKB:O95398] synonym: "Rap1 guanine-nucleotide-exchange factor directly activated by cAMP" EXACT [UniProtKB:O95398] xref: EMBL:AAC83381.1 xref: EMBL:AAD02890.1 xref: EMBL:AAD12740.1 xref: EMBL:AAH17728.1 xref: UniProtKB:O95398 xref: UniProtKB:O95634 xref: UniProtKB:Q8WVN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019786 ! RAPGEF3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0004464 ! cAMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0054758 name: ZFYV9_HUMAN def: "Zinc finger FYVE domain-containing protein 9" [UniProtKB:O95405] synonym: "hSARA" EXACT [UniProtKB:O95405] synonym: "Madh-interacting protein" EXACT [UniProtKB:O95405] synonym: "Mothers against decapentaplegic homolog-interacting protein" EXACT [UniProtKB:O95405] synonym: "Novel serine protease" EXACT [UniProtKB:O95405] synonym: "NSP" EXACT [UniProtKB:O95405] synonym: "Receptor activation anchor" EXACT [UniProtKB:O95405] synonym: "Smad anchor for receptor activation" EXACT [UniProtKB:O95405] xref: EMBL:AAC99462.1 xref: EMBL:AAD31694.1 xref: EMBL:AAD31695.1 xref: EMBL:AAH32680.1 xref: UniProtKB:O95405 xref: UniProtKB:Q9UNE1 xref: UniProtKB:Q9Y5R7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020600 ! ZFYVE9_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0008961 ! smad3-zfyve9-1 direct interaction relationship: participates_in CCO:I0017662 ! st7-madhip-2 physical interaction relationship: participates_in CCO:I0019338 ! st7-madhip-1 physical interaction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000721 ! transforming growth factor beta receptor complex assembly relationship: participates_in CCO:P0000723 ! SMAD protein complex assembly relationship: participates_in CCO:P0000724 ! SMAD protein nuclear translocation [Term] id: CCO:B0054759 name: CNIH_HUMAN def: "Protein cornichon homolog" [UniProtKB:O95406] synonym: "T-cell growth-associated molecule 77" EXACT [UniProtKB:O95406] synonym: "TGAM77" EXACT [UniProtKB:O95406] xref: EMBL:AAC98388.1 xref: EMBL:AAD20960.1 xref: EMBL:AAD32301.1 xref: EMBL:AAI03742.1 xref: EMBL:AAQ88998.1 xref: UniProtKB:O95406 xref: UniProtKB:Q3SYM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017404 ! CNIH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0054760 name: TNR6B_HUMAN def: "Tumor necrosis factor receptor superfamily member 6B precursor" [UniProtKB:O95407] synonym: "DcR3" EXACT [UniProtKB:O95407] synonym: "Decoy receptor 3" EXACT [UniProtKB:O95407] synonym: "Decoy receptor for Fas ligand" EXACT [UniProtKB:O95407] synonym: "M68" EXACT [UniProtKB:O95407] xref: EMBL:AAD03056.1 xref: EMBL:AAD29688.1 xref: EMBL:AAF33685.1 xref: EMBL:AAF33686.1 xref: EMBL:AAF35244.1 xref: EMBL:AAH17065.1 xref: EMBL:AAH34349.1 xref: EMBL:AAQ88646.1 xref: EMBL:CAC03668.1 xref: UniProtKB:O95407 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020321 ! TNFRSF6B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0016260 ! tr6-light physical interaction relationship: participates_in CCO:I0016261 ! light-tr6 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054761 name: TIAF1_HUMAN def: "TGFB1-induced anti-apoptotic factor 1" [UniProtKB:O95411] synonym: "12 kDa TGF-beta-1-induced antiapoptotic factor" EXACT [UniProtKB:O95411] xref: EMBL:AAD04172.1 xref: EMBL:AAH47669.1 xref: EMBL:AAH58075.1 xref: UniProtKB:O95411 xref: UniProtKB:Q6PEG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020259 ! TIAF1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0054762 name: SVIL_HUMAN def: "Supervillin" [UniProtKB:O95425] synonym: "Archvillin" EXACT [UniProtKB:O95425] synonym: "p205/p250" EXACT [UniProtKB:O95425] xref: EMBL:AAC64695.1 xref: EMBL:AAC64696.1 xref: EMBL:AAD14682.1 xref: EMBL:CAH71300.1 xref: EMBL:CAH71301.1 xref: EMBL:CAI15236.1 xref: EMBL:CAI15237.1 xref: UniProtKB:O60611 xref: UniProtKB:O60612 xref: UniProtKB:O95425 xref: UniProtKB:Q5VZK5 xref: UniProtKB:Q5VZK6 xref: UniProtKB:Q9H1R7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020083 ! SVIL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:I0020469 ! svil-luc7l2 physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0071010 ! SVIL_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0071011 ! SVIL_HUMAN-Phosphoserine245 relationship: transforms_into CCO:B0071012 ! SVIL_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0071013 ! SVIL_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0071014 ! SVIL_HUMAN-Phosphoserine673 relationship: transforms_into CCO:B0071015 ! SVIL_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0071016 ! SVIL_HUMAN-Phosphothreonine736 relationship: transforms_into CCO:B0071017 ! SVIL_HUMAN-Phosphothreonine852 relationship: transforms_into CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: transforms_into CCO:B0071019 ! SVIL_HUMAN-Phosphothreonine1175 [Term] id: CCO:B0054763 name: BAG4_HUMAN def: "BAG family molecular chaperone regulator 4" [UniProtKB:O95429] synonym: "BAG-4" EXACT [UniProtKB:O95429] synonym: "Bcl-2-associated athanogene 4" EXACT [UniProtKB:O95429] synonym: "Silencer of death domains" EXACT [UniProtKB:O95429] xref: EMBL:AAD05226.1 xref: EMBL:AAD16123.2 xref: EMBL:AAH38505.2 xref: UniProtKB:O95429 xref: UniProtKB:O95818 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017118 ! BAG4_human relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054764 name: CXB6_HUMAN def: "Gap junction beta-6 protein" [UniProtKB:O95452] synonym: "Connexin-30" EXACT [UniProtKB:O95452] synonym: "Cx30" EXACT [UniProtKB:O95452] xref: EMBL:AAH38934.1 xref: EMBL:AAP51162.1 xref: EMBL:AAV67951.1 xref: EMBL:AAV67952.1 xref: EMBL:AAV67953.1 xref: EMBL:BAF82281.1 xref: EMBL:CAA06611.1 xref: EMBL:CAI14832.1 xref: EMBL:EAX08254.1 xref: UniProtKB:O95452 xref: UniProtKB:Q5Q1H9 xref: UniProtKB:Q5Q1I0 xref: UniProtKB:Q5Q1I1 xref: UniProtKB:Q5T5U0 xref: UniProtKB:Q8IUP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017495 ! GJB6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000473 ! gap junction relationship: located_in CCO:C0000474 ! connexon complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0054765 name: GNAS3_HUMAN def: "Neuroendocrine secretory protein 55" [UniProtKB:O95467] synonym: "NESP55" EXACT [UniProtKB:O95467] xref: EMBL:AAD11804.1 xref: EMBL:AAF63226.1 xref: EMBL:CAA08889.1 xref: EMBL:CAB83214.1 xref: UniProtKB:O95417 xref: UniProtKB:O95467 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017944 ! GNAS_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004863 ! mu-type opioid receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0001374 ! vesicle relationship: located_in CCO:C0001638 ! sarcolemma relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway [Term] id: CCO:B0054766 name: SIX6_HUMAN def: "Homeobox protein SIX6" [UniProtKB:O95475] synonym: "Homeodomain protein OPTX2" EXACT [UniProtKB:O95475] synonym: "Optic homeobox 2" EXACT [UniProtKB:O95475] synonym: "Sine oculis homeobox homolog 6" EXACT [UniProtKB:O95475] xref: EMBL:AAD49844.1 xref: EMBL:AAF04402.1 xref: EMBL:AAH69413.2 xref: EMBL:BAA94484.1 xref: EMBL:CAA09773.1 xref: UniProtKB:O95475 xref: UniProtKB:Q6NT42 xref: UniProtKB:Q9P1X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019925 ! SIX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054767 name: LPHN2_HUMAN def: "Latrophilin-2 precursor" [UniProtKB:O95490] synonym: "Calcium-independent alpha-latrotoxin receptor 2" EXACT [UniProtKB:O95490] synonym: "Latrophilin homolog 1" EXACT [UniProtKB:O95490] synonym: "Lectomedin-1" EXACT [UniProtKB:O95490] xref: EMBL:AAD54675.1 xref: EMBL:AAD54676.1 xref: EMBL:AAD54677.1 xref: EMBL:BAA34506.1 xref: EMBL:CAA10458.1 xref: EMBL:CAB60229.1 xref: EMBL:CAH71347.1 xref: EMBL:CAI22401.1 xref: UniProtKB:O94882 xref: UniProtKB:O95490 xref: UniProtKB:Q5VX76 xref: UniProtKB:Q9UKY5 xref: UniProtKB:Q9UKY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018517 ! LPHN2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0003197 ! latrotoxin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0067767 ! LPHN2_HUMAN-Phosphoserine1381 relationship: transforms_into CCO:B0067768 ! LPHN2_HUMAN-Phosphoserine1387 [Term] id: CCO:B0054768 name: VNN1_HUMAN def: "Pantetheinase precursor" [UniProtKB:O95497] synonym: "EC 3.5.1.92" EXACT [UniProtKB:O95497] synonym: "Pantetheine hydrolase" EXACT [UniProtKB:O95497] synonym: "Tiff66" EXACT [UniProtKB:O95497] synonym: "Vanin-1" EXACT [UniProtKB:O95497] synonym: "Vascular non-inflammatory molecule 1" EXACT [UniProtKB:O95497] xref: EMBL:AAF21453.1 xref: EMBL:AAH96265.1 xref: EMBL:AAH96266.1 xref: EMBL:AAH96267.1 xref: EMBL:AAH96268.1 xref: EMBL:AAY88742.1 xref: EMBL:CAA10568.1 xref: EMBL:CAB40075.1 xref: UniProtKB:O95497 xref: UniProtKB:Q4JFW6 xref: UniProtKB:Q4VAS7 xref: UniProtKB:Q4VAS8 xref: UniProtKB:Q4VAS9 xref: UniProtKB:Q9UF16 xref: UniProtKB:Q9UJF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020459 ! VNN1_human relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_function CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides relationship: has_function CCO:F0003599 ! pantetheine hydrolase activity relationship: has_function CCO:F0005537 ! GPI anchor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0001777 ! positive regulation of T cell differentiation in the thymus [Term] id: CCO:B0054769 name: O95499_HUMAN def: "Olfactory receptor 89 (Olfactory receptor OR6-17)" [UniProtKB:O95499] xref: EMBL:CAA10602.1 xref: EMBL:DAA04833.1 xref: UniProtKB:O95499 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021076 ! olfr89_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054770 name: CBX6_HUMAN def: "Chromobox protein homolog 6" [UniProtKB:O95503] xref: EMBL:AAH12111.1 xref: EMBL:AAH64900.1 xref: EMBL:CAA15431.1 xref: UniProtKB:O95503 xref: UniProtKB:Q96EM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017251 ! CBX6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064103 ! CBX6_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0064104 ! CBX6_HUMAN-Phosphoserine303 [Term] id: CCO:B0054771 name: TTRAP_HUMAN def: "TRAF and TNF receptor-associated protein" [UniProtKB:O95551] synonym: "EAPII" EXACT [UniProtKB:O95551] synonym: "ETS1-associated protein 2" EXACT [UniProtKB:O95551] synonym: "ETS1-associated protein II" EXACT [UniProtKB:O95551] xref: EMBL:AAF64144.1 xref: EMBL:AAG35600.1 xref: EMBL:AAH17553.1 xref: EMBL:AAI10376.1 xref: EMBL:AAT09764.1 xref: EMBL:BAA92119.1 xref: EMBL:CAA21141.1 xref: EMBL:CAB92966.1 xref: EMBL:CAD92510.1 xref: UniProtKB:O95551 xref: UniProtKB:Q2TBE2 xref: UniProtKB:Q5JYM0 xref: UniProtKB:Q7Z6U5 xref: UniProtKB:Q9NUK5 xref: UniProtKB:Q9NYY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020381 ! TTRAP_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054772 name: KLF8_HUMAN def: "Krueppel-like factor 8" [UniProtKB:O95600] synonym: "Basic krueppel-like factor 3" EXACT [UniProtKB:O95600] synonym: "Zinc finger protein 741" EXACT [UniProtKB:O95600] xref: EMBL:AAC99849.1 xref: EMBL:AAI05131.1 xref: EMBL:AAI12110.1 xref: EMBL:BAD92241.1 xref: EMBL:CAE46033.1 xref: EMBL:CAI41397.1 xref: EMBL:CAI42343.1 xref: UniProtKB:O95600 xref: UniProtKB:Q2M246 xref: UniProtKB:Q59GV5 xref: UniProtKB:Q5HYQ5 xref: UniProtKB:Q5JXP7 xref: UniProtKB:Q6MZJ7 xref: UniProtKB:Q9UGC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018423 ! KLF8_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054773 name: ADCY5_HUMAN def: "Adenylate cyclase type 5" [UniProtKB:O95622] synonym: "Adenylate cyclase type V" EXACT [UniProtKB:O95622] synonym: "Adenylyl cyclase 5" EXACT [UniProtKB:O95622] synonym: "ATP pyrophosphate-lyase 5" EXACT [UniProtKB:O95622] synonym: "EC 4.6.1.1" EXACT [UniProtKB:O95622] xref: EMBL:AAD00121.1 xref: EMBL:AAM94374.1 xref: EMBL:DAA00057.1 xref: UniProtKB:O95622 xref: UniProtKB:Q7RTV7 xref: UniProtKB:Q8NFM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016911 ! ADCY5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000517 ! adenosine receptor signaling pathway relationship: participates_in CCO:P0000730 ! dopamine receptor, adenylate cyclase activating pathway relationship: participates_in CCO:P0000733 ! dopamine receptor, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0065404 ! ADCY5_HUMAN-Phosphoserine8 [Term] id: CCO:B0054774 name: ZBT11_HUMAN def: "Zinc finger and BTB domain-containing protein 11" [UniProtKB:O95625] xref: EMBL:AAD00172.1 xref: EMBL:AAI11701.1 xref: EMBL:BAG35711.1 xref: EMBL:EAW79786.1 xref: UniProtKB:O95625 xref: UniProtKB:Q2NKP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020544 ! ZBTB11_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054775 name: CNOT4_HUMAN def: "CCR4-NOT transcription complex subunit 4" [UniProtKB:O95628] synonym: "CCR4-associated factor 4" EXACT [UniProtKB:O95628] synonym: "E3 ubiquitin-protein ligase CNOT4" EXACT [UniProtKB:O95628] synonym: "EC 6.3.2.-" EXACT [UniProtKB:O95628] synonym: "Potential transcriptional repressor NOT4Hp" EXACT [UniProtKB:O95628] xref: EMBL:AAC72963.1 xref: EMBL:AAD00179.1 xref: EMBL:AAD00180.1 xref: EMBL:AAF29829.1 xref: EMBL:AAH35590.1 xref: EMBL:BAC11125.1 xref: EMBL:CAB97536.1 xref: UniProtKB:O95339 xref: UniProtKB:O95627 xref: UniProtKB:O95628 xref: UniProtKB:Q8IYM7 xref: UniProtKB:Q8NCL0 xref: UniProtKB:Q9NPQ1 xref: UniProtKB:Q9NZN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017409 ! CNOT4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064429 ! CNOT4_HUMAN-Phosphoserine71 [Term] id: CCO:B0054776 name: STABP_HUMAN def: "STAM-binding protein" [UniProtKB:O95630] synonym: "Associated molecule with the SH3 domain of STAM" EXACT [UniProtKB:O95630] synonym: "EC 3.1.2.15" EXACT [UniProtKB:O95630] xref: EMBL:AAD05037.1 xref: EMBL:AAH07682.1 xref: EMBL:AAH65574.1 xref: EMBL:AAI01468.1 xref: EMBL:AAI01470.1 xref: EMBL:AAX88908.1 xref: UniProtKB:O95630 xref: UniProtKB:Q3MJE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020059 ! STAMBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015828 ! grap2-stambp physical interaction relationship: participates_in CCO:I0015829 ! stam2-stambp physical interaction relationship: participates_in CCO:I0016028 ! rn11-amsh-2 physical interaction relationship: participates_in CCO:I0016029 ! rn11-amsh-3 physical interaction relationship: participates_in CCO:I0016338 ! stambp-stam-2 physical interaction relationship: participates_in CCO:I0016341 ! stambp-stam-3 physical interaction relationship: participates_in CCO:I0018145 ! rnf11-amsh-1 physical interaction relationship: participates_in CCO:I0019463 ! stambp-stam-1 physical interaction relationship: participates_in CCO:I0020651 ! recql5-stambp physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0070947 ! STABP_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0070948 ! STABP_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0070949 ! STABP_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0070950 ! STABP_HUMAN-Phosphoserine245 relationship: transforms_into CCO:B0070951 ! STABP_HUMAN-Phosphoserine247 [Term] id: CCO:B0054777 name: NET1_HUMAN def: "Netrin-1 precursor" [UniProtKB:O95631] xref: EMBL:AAD09221.1 xref: UniProtKB:O95631 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018754 ! NTN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0001277 ! negative regulation of axon extension relationship: participates_in CCO:P0002548 ! positive regulation of axon extension [Term] id: CCO:B0054778 name: FSTL3_HUMAN def: "Follistatin-related protein 3 precursor" [UniProtKB:O95633] synonym: "Follistatin-like 3" EXACT [UniProtKB:O95633] synonym: "Follistatin-related gene protein" EXACT [UniProtKB:O95633] xref: EMBL:AAC64321.1 xref: EMBL:AAH05839.1 xref: EMBL:AAH33119.1 xref: EMBL:AAQ89276.1 xref: UniProtKB:O95633 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017842 ! FSTL3_human relationship: has_function CCO:F0003570 ! activin inhibitor activity relationship: has_function CCO:F0007319 ! activin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway [Term] id: CCO:B0054779 name: NFAC1_HUMAN def: "Nuclear factor of activated T-cells, cytoplasmic 1" [UniProtKB:O95644] synonym: "NF-ATc" EXACT [UniProtKB:O95644] synonym: "NF-ATc1" EXACT [UniProtKB:O95644] synonym: "NFAT transcription complex cytosolic component" EXACT [UniProtKB:O95644] synonym: "NFATc" EXACT [UniProtKB:O95644] xref: EMBL:AAA19601.1 xref: EMBL:AAC50869.1 xref: EMBL:AAD00450.1 xref: EMBL:AAD00451.1 xref: EMBL:AAD00452.1 xref: UniProtKB:O95644 xref: UniProtKB:Q12865 xref: UniProtKB:Q15793 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018765 ! NFATC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068603 ! NFAC1_HUMAN-Phosphoserine117 [Term] id: CCO:B0054780 name: NTR2_HUMAN def: "Neurotensin receptor type 2" [UniProtKB:O95665] synonym: "Levocabastine-sensitive neurotensin receptor" EXACT [UniProtKB:O95665] synonym: "NT-R-2" EXACT [UniProtKB:O95665] synonym: "NTR2 receptor" EXACT [UniProtKB:O95665] xref: EMBL:AAH22501.1 xref: EMBL:AAH37776.1 xref: EMBL:AAR07902.1 xref: EMBL:CAA71233.1 xref: UniProtKB:O95665 xref: UniProtKB:Q8IY58 xref: UniProtKB:Q8TBH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018884 ! NTSR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003173 ! neurotensin receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054781 name: ECEL1_HUMAN def: "Endothelin-converting enzyme-like 1" [UniProtKB:O95672] synonym: "EC 3.4.24.-" EXACT [UniProtKB:O95672] synonym: "Xce protein" EXACT [UniProtKB:O95672] xref: EMBL:AAH50453.2 xref: EMBL:AAQ89282.1 xref: EMBL:AAY24101.1 xref: EMBL:AAZ22338.1 xref: EMBL:CAA76113.1 xref: EMBL:CAB86601.1 xref: UniProtKB:O95672 xref: UniProtKB:Q45UD9 xref: UniProtKB:Q53RF9 xref: UniProtKB:Q6UW86 xref: UniProtKB:Q86TH4 xref: UniProtKB:Q9NY95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017652 ! ECEL1_human relationship: has_function CCO:F0000691 ! neprilysin activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054782 name: EYA4_HUMAN def: "Eyes absent homolog 4" [UniProtKB:O95677] synonym: "EC 3.1.3.48" EXACT [UniProtKB:O95677] xref: EMBL:AAH41063.1 xref: EMBL:CAA07816.1 xref: EMBL:CAA07817.1 xref: EMBL:CAA76636.1 xref: EMBL:CAA76891.1 xref: EMBL:CAB92069.2 xref: EMBL:CAI41272.1 xref: EMBL:CAI42524.1 xref: UniProtKB:O95464 xref: UniProtKB:O95677 xref: UniProtKB:O95679 xref: UniProtKB:Q8IW39 xref: UniProtKB:Q9NTR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017749 ! EYA4_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065186 ! EYA4_HUMAN-Phosphoserine361 [Term] id: CCO:B0054783 name: FR1OP_HUMAN def: "FGFR1 oncogene partner" [UniProtKB:O95684] xref: EMBL:AAH11902.1 xref: EMBL:AAH37785.1 xref: EMBL:CAA77020.1 xref: EMBL:CAI19642.1 xref: EMBL:CAI19643.1 xref: UniProtKB:O95684 xref: UniProtKB:Q49AI0 xref: UniProtKB:Q5R3F6 xref: UniProtKB:Q96EW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017831 ! FGFR1OP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0066275 ! FR1OP_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0066276 ! FR1OP_HUMAN-Phosphoserine160 relationship: transforms_into CCO:B0066277 ! FR1OP_HUMAN-Phosphotyrosine337 [Term] id: CCO:B0054784 name: LY86_HUMAN def: "Lymphocyte antigen 86 precursor" [UniProtKB:O95711] synonym: "Protein MD-1" EXACT [UniProtKB:O95711] xref: EMBL:AAC98152.2 xref: EMBL:AAH38846.1 xref: EMBL:BAA76410.1 xref: EMBL:CAB76262.1 xref: UniProtKB:O95711 xref: UniProtKB:Q9UQC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018533 ! LY86_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054785 name: RAB3D_HUMAN def: "Ras-related protein Rab-3D" [UniProtKB:O95716] xref: EMBL:AAC72918.1 xref: EMBL:AAH16471.1 xref: EMBL:AAM21081.1 xref: UniProtKB:O95716 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019596 ! RAB3D_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001660 ! zymogen granule relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069685 ! RAB3D_HUMAN-Cysteine methyl ester219 [Term] id: CCO:B0054786 name: O95724_HUMAN def: "Reverse transcriptase" [UniProtKB:O95724] xref: EMBL:CAA13575.1 xref: UniProtKB:O95724 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021077 ! pol_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054787 name: O95725_HUMAN def: "Reverse transcriptase" [UniProtKB:O95725] xref: EMBL:CAA13576.1 xref: UniProtKB:O95725 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021077 ! pol_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054788 name: O95740_HUMAN def: "Squamous cell carcinoma antigen 2" [UniProtKB:O95740] xref: EMBL:BAA75462.1 xref: UniProtKB:O95740 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001246 ! regulation of proteolysis [Term] id: CCO:B0054789 name: O95745_HUMAN def: "PMS2L15 protein" [UniProtKB:O95745] xref: EMBL:BAA74755.1 xref: UniProtKB:O95745 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021078 ! PMS2L15_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0054790 name: PM2LG_HUMAN def: "Postmeiotic segregation increased 2-like protein 16" [UniProtKB:O95746] xref: EMBL:BAA74756.1 xref: UniProtKB:O95746 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019455 ! PMS2L16_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0054791 name: OXSR1_HUMAN def: "Serine/threonine-protein kinase OSR1" [UniProtKB:O95747] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O95747] synonym: "Oxidative stress-responsive 1 protein" EXACT [UniProtKB:O95747] xref: EMBL:AAH08726.1 xref: EMBL:AAP97192.1 xref: EMBL:ABA27097.1 xref: EMBL:BAA75674.1 xref: EMBL:BAA83053.2 xref: UniProtKB:O95747 xref: UniProtKB:Q3LR53 xref: UniProtKB:Q7Z501 xref: UniProtKB:Q9UPQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019255 ! OXSR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0069010 ! OXSR1_HUMAN-Phosphoserine339 relationship: transforms_into CCO:B0069011 ! OXSR1_HUMAN-Phosphoserine427 [Term] id: CCO:B0054792 name: RAB36_HUMAN def: "Ras-related protein Rab-36" [UniProtKB:O95755] xref: EMBL:AAF02485.1 xref: EMBL:AAI04990.1 xref: EMBL:AAI04992.1 xref: EMBL:AAQ16115.1 xref: EMBL:BAA75195.1 xref: EMBL:CAG30439.1 xref: UniProtKB:O95755 xref: UniProtKB:Q2M390 xref: UniProtKB:Q7Z4A9 xref: UniProtKB:Q9UHP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019591 ! RAB36_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054793 name: TBCD8_HUMAN def: "TBC1 domain family member 8" [UniProtKB:O95759] synonym: "AD 3" EXACT [UniProtKB:O95759] synonym: "Vascular Rab-GAP/TBC-containing protein" EXACT [UniProtKB:O95759] xref: EMBL:AAY14824.1 xref: EMBL:BAA75489.1 xref: EMBL:BAA76517.1 xref: UniProtKB:A6NDL4 xref: UniProtKB:O95759 xref: UniProtKB:Q53SQ4 xref: UniProtKB:Q9UQ32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020183 ! TBC1D8_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0054794 name: GPR75_HUMAN def: "Probable G-protein coupled receptor 75" [UniProtKB:O95800] xref: EMBL:AAD19849.1 xref: EMBL:AAD22770.1 xref: EMBL:AAH67475.1 xref: EMBL:AAH67476.1 xref: EMBL:AAY15018.1 xref: UniProtKB:O95800 xref: UniProtKB:Q6NWR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018031 ! GPR75_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054795 name: CER1_HUMAN def: "Cerberus precursor" [UniProtKB:O95813] synonym: "Cerberus-related protein" EXACT [UniProtKB:O95813] synonym: "DAN domain family member 4" EXACT [UniProtKB:O95813] xref: EMBL:AAD19879.1 xref: EMBL:AAH69371.1 xref: EMBL:AAH69405.1 xref: EMBL:AAH69491.1 xref: EMBL:AAH69503.1 xref: EMBL:AAK92484.1 xref: EMBL:CAH73850.1 xref: UniProtKB:O95813 xref: UniProtKB:Q6ISJ1 xref: UniProtKB:Q6ISJ6 xref: UniProtKB:Q6ISQ2 xref: UniProtKB:Q6ISS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017335 ! CER1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway [Term] id: CCO:B0054796 name: BAG3_HUMAN def: "BAG family molecular chaperone regulator 3" [UniProtKB:O95817] synonym: "BAG-3" EXACT [UniProtKB:O95817] synonym: "Bcl-2-associated athanogene 3" EXACT [UniProtKB:O95817] synonym: "Bcl-2-binding protein Bis" EXACT [UniProtKB:O95817] synonym: "Docking protein CAIR-1" EXACT [UniProtKB:O95817] xref: EMBL:AAD16122.2 xref: EMBL:AAF26839.1 xref: EMBL:AAF69592.2 xref: EMBL:AAH06418.1 xref: EMBL:AAH14656.1 xref: EMBL:AAI07787.1 xref: EMBL:CAB70824.1 xref: UniProtKB:O95817 xref: UniProtKB:Q3B763 xref: UniProtKB:Q9NT20 xref: UniProtKB:Q9P120 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017117 ! BAG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015317 ! bag3-q8wu02 physical interaction relationship: participates_in CCO:I0015536 ! bag3-dvl2 physical interaction relationship: participates_in CCO:I0015656 ! bag3-hspb8-1 physical interaction relationship: participates_in CCO:I0015660 ! bag3-dazap2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0063692 ! BAG3_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0063693 ! BAG3_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0063694 ! BAG3_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0063695 ! BAG3_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0063696 ! BAG3_HUMAN-Phosphoserine194 relationship: transforms_into CCO:B0063697 ! BAG3_HUMAN-Phosphotyrosine240 relationship: transforms_into CCO:B0063698 ! BAG3_HUMAN-Phosphotyrosine247 relationship: transforms_into CCO:B0063699 ! BAG3_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0063700 ! BAG3_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0063701 ! BAG3_HUMAN-Phosphothreonine285 relationship: transforms_into CCO:B0063702 ! BAG3_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0063703 ! BAG3_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0063704 ! BAG3_HUMAN-Phosphoserine377 [Term] id: CCO:B0054797 name: DCMC_HUMAN def: "Malonyl-CoA decarboxylase, mitochondrial precursor" [UniProtKB:O95822] synonym: "EC 4.1.1.9" EXACT [UniProtKB:O95822] synonym: "MCD" EXACT [UniProtKB:O95822] xref: EMBL:AAD16177.2 xref: EMBL:AAD34631.1 xref: EMBL:AAD48994.1 xref: EMBL:AAH00286.1 xref: EMBL:AAH52592.1 xref: UniProtKB:O95822 xref: UniProtKB:Q9UNU5 xref: UniProtKB:Q9Y3F2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017534 ! MLYCD_human relationship: has_function CCO:F0000889 ! methylmalonyl-CoA decarboxylase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003398 ! carboxy-lyase activity relationship: has_function CCO:F0007433 ! malonyl-CoA decarboxylase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0001518 ! regulation of fatty acid beta-oxidation relationship: transforms_into CCO:B0064658 ! DCMC_HUMAN-Phosphoserine387 [Term] id: CCO:B0054798 name: CLIC3_HUMAN def: "Chloride intracellular channel protein 3" [UniProtKB:O95833] xref: EMBL:AAD16450.1 xref: EMBL:AAH07012.2 xref: EMBL:CAI12764.1 xref: EMBL:EAW88329.1 xref: UniProtKB:O95833 xref: UniProtKB:Q5SPZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017386 ! CLIC3_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001515 ! voltage-gated chloride channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054799 name: ANGL1_HUMAN def: "Angiopoietin-related protein 1 precursor" [UniProtKB:O95841] synonym: "ANG-3" EXACT [UniProtKB:O95841] synonym: "Angiopoietin-3" EXACT [UniProtKB:O95841] synonym: "Angiopoietin-like 1" EXACT [UniProtKB:O95841] xref: EMBL:AAD19608.1 xref: EMBL:AAH50640.1 xref: EMBL:AAQ88645.1 xref: EMBL:BAB40691.1 xref: EMBL:CAC13169.1 xref: EMBL:CAI21921.1 xref: UniProtKB:O95841 xref: UniProtKB:Q5T5Z5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016965 ! ANGPTL1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054800 name: GUC1C_HUMAN def: "Guanylyl cyclase-activating protein 3" [UniProtKB:O95843] synonym: "GCAP 3" EXACT [UniProtKB:O95843] synonym: "Guanylate cyclase activator 1C" EXACT [UniProtKB:O95843] xref: EMBL:AAD19943.1 xref: EMBL:AAD19944.1 xref: EMBL:AAD19945.1 xref: UniProtKB:O95843 xref: UniProtKB:O95844 xref: UniProtKB:Q9UNM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018092 ! GUCA1C_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001692 ! calcium sensitive guanylate cyclase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054801 name: DDAH2_HUMAN def: "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2" [UniProtKB:O95865] synonym: "DDAH-2" EXACT [UniProtKB:O95865] synonym: "DDAHII" EXACT [UniProtKB:O95865] synonym: "Dimethylargininase-2" EXACT [UniProtKB:O95865] synonym: "Dimethylarginine dimethylaminohydrolase 2" EXACT [UniProtKB:O95865] synonym: "EC 3.5.3.18" EXACT [UniProtKB:O95865] synonym: "Protein G6a" EXACT [UniProtKB:O95865] synonym: "S-phase protein" EXACT [UniProtKB:O95865] xref: EMBL:AAD18074.1 xref: EMBL:AAD20973.1 xref: EMBL:AAH01435.1 xref: EMBL:AAP97193.1 xref: EMBL:BAB63377.1 xref: EMBL:CAB46079.1 xref: EMBL:CAI17820.1 xref: EMBL:CAI18413.1 xref: EMBL:CAM26098.1 xref: EMBL:CAM45772.1 xref: EMBL:CAQ07022.1 xref: EMBL:CAQ08895.1 xref: EMBL:CAQ10110.1 xref: EMBL:EAX03500.1 xref: UniProtKB:A2BEZ7 xref: UniProtKB:O95865 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017538 ! DDAH2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003126 ! dimethylargininase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction [Term] id: CCO:B0054802 name: O95880_HUMAN def: "Putative uncharacterized protein" [UniProtKB:O95880] xref: EMBL:AAD20031.1 xref: EMBL:AAD50079.1 xref: UniProtKB:O95880 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054803 name: SGT1_HUMAN def: "Protein SGT1" [UniProtKB:O95905] synonym: "Ecdysoneless homolog" EXACT [UniProtKB:O95905] synonym: "hSGT1" EXACT [UniProtKB:O95905] synonym: "Suppressor of GCR2" EXACT [UniProtKB:O95905] xref: EMBL:AAH00721.1 xref: EMBL:BAA75199.1 xref: UniProtKB:O95905 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019884 ! ECD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000623 ! regulation of glycolysis relationship: transforms_into CCO:B0070455 ! SGT1_HUMAN-Phosphoserine503 relationship: transforms_into CCO:B0070456 ! SGT1_HUMAN-Phosphoserine505 relationship: transforms_into CCO:B0070457 ! SGT1_HUMAN-Phosphoserine518 [Term] id: CCO:B0054804 name: OR2H2_HUMAN def: "Olfactory receptor 2H2" [UniProtKB:O95918] synonym: "Hs6M1-12" EXACT [UniProtKB:O95918] synonym: "Olfactory receptor-like protein FAT11" EXACT [UniProtKB:O95918] xref: EMBL:AAB36567.1 xref: EMBL:AAF98751.1 xref: EMBL:AAF98752.1 xref: EMBL:AAF98753.1 xref: EMBL:AAF98754.1 xref: EMBL:AAH69146.1 xref: EMBL:AAI12177.1 xref: EMBL:AAK95116.1 xref: EMBL:BAC06177.1 xref: EMBL:CAA21455.1 xref: EMBL:CAI17387.1 xref: UniProtKB:O95918 xref: UniProtKB:Q15062 xref: UniProtKB:Q2M1Y3 xref: UniProtKB:Q5STL8 xref: UniProtKB:Q6NTB7 xref: UniProtKB:Q96R14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019098 ! OR2H2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054805 name: CBX7_HUMAN def: "Chromobox protein homolog 7" [UniProtKB:O95931] xref: EMBL:AAH51773.1 xref: EMBL:CAB36555.1 xref: UniProtKB:O95931 xref: UniProtKB:Q86T17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017252 ! CBX7_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054806 name: EOMES_HUMAN def: "Eomesodermin homolog" [UniProtKB:O95936] xref: EMBL:AAH25363.1 xref: EMBL:BAA83417.1 xref: EMBL:CAB37939.1 xref: UniProtKB:O95936 xref: UniProtKB:Q8TAZ2 xref: UniProtKB:Q9UPM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017718 ! EOMES_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054807 name: NCTR2_HUMAN def: "Natural cytotoxicity triggering receptor 2 precursor" [UniProtKB:O95944] synonym: "CD336 antigen" EXACT [UniProtKB:O95944] synonym: "Lymphocyte antigen 95 homolog" EXACT [UniProtKB:O95944] synonym: "Natural killer cell p44-related protein" EXACT [UniProtKB:O95944] synonym: "NK cell-activating receptor" EXACT [UniProtKB:O95944] synonym: "NK-p44" EXACT [UniProtKB:O95944] synonym: "NKp44" EXACT [UniProtKB:O95944] xref: EMBL:CAB39168.1 xref: EMBL:CAB52289.1 xref: EMBL:CAB52290.1 xref: EMBL:CAC09452.3 xref: EMBL:CAC09453.3 xref: EMBL:CAC09454.3 xref: UniProtKB:O95944 xref: UniProtKB:Q9H562 xref: UniProtKB:Q9H563 xref: UniProtKB:Q9H564 xref: UniProtKB:Q9UMT1 xref: UniProtKB:Q9UMT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018733 ! NCR2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054808 name: O95958_HUMAN def: "Lost in inflammatory breast cancer tumor suppressor protein" [UniProtKB:O95958] synonym: "WNT1 inducible signaling pathway protein 3" EXACT [UniProtKB:O95958] synonym: "WNT1 inducible signaling pathway protein 3, isoform CRA_d" EXACT [UniProtKB:O95958] xref: EMBL:AAD31517.1 xref: EMBL:CAB16556.1 xref: EMBL:EAW48276.1 xref: UniProtKB:O95958 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021079 ! LIBC_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0054809 name: ITGBL_HUMAN def: "Integrin beta-like protein 1 precursor" [UniProtKB:O95965] synonym: "Osteoblast-specific cysteine-rich protein" EXACT [UniProtKB:O95965] synonym: "Ten integrin EGF-like repeat domain-containing protein" EXACT [UniProtKB:O95965] xref: EMBL:AAD17666.1 xref: EMBL:AAH36788.2 xref: EMBL:AAN16024.1 xref: EMBL:BAF84029.1 xref: EMBL:CAB94388.1 xref: EMBL:CAH71455.1 xref: EMBL:CAH73400.1 xref: EMBL:CAI14550.1 xref: EMBL:EAX09052.1 xref: UniProtKB:A8K5M5 xref: UniProtKB:O95965 xref: UniProtKB:Q8N172 xref: UniProtKB:Q9NPR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018344 ! ITGBL1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000544 ! integrin complex relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0054810 name: LGI1_HUMAN def: "Leucine-rich glioma-inactivated protein 1 precursor" [UniProtKB:O95970] synonym: "Epitempin-1" EXACT [UniProtKB:O95970] xref: EMBL:AAC99316.1 xref: EMBL:AAH22500.1 xref: EMBL:AAM22074.1 xref: EMBL:AAQ89244.1 xref: EMBL:CAH73837.1 xref: EMBL:CAH73838.1 xref: EMBL:CAI14981.1 xref: EMBL:CAI14982.1 xref: UniProtKB:O95970 xref: UniProtKB:Q5W001 xref: UniProtKB:Q5W002 xref: UniProtKB:Q8NI23 xref: UniProtKB:Q96LF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018480 ! LGI1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054811 name: BY55_HUMAN def: "CD160 antigen precursor" [UniProtKB:O95971] synonym: "CD160 antigen" EXACT [UniProtKB:O95971] synonym: "Natural killer cell receptor BY55" EXACT [UniProtKB:O95971] xref: EMBL:AAC72302.1 xref: EMBL:AAH14465.1 xref: UniProtKB:O95971 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017191 ! CD160_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004977 ! MHC class I receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001959 ! anchored to plasma membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054812 name: IGSF6_HUMAN def: "Immunoglobulin superfamily member 6 precursor" [UniProtKB:O95976] synonym: "Protein DORA" EXACT [UniProtKB:O95976] xref: EMBL:AAH17844.1 xref: EMBL:CAA11155.1 xref: UniProtKB:O95976 xref: UniProtKB:Q8WWD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018241 ! IGSF6_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054813 name: S1PR4_HUMAN def: "Sphingosine 1-phosphate receptor 4" [UniProtKB:O95977] synonym: "Endothelial differentiation G-protein coupled receptor 6" EXACT [UniProtKB:O95977] synonym: "S1P receptor 4" EXACT [UniProtKB:O95977] synonym: "S1P receptor Edg-6" EXACT [UniProtKB:O95977] synonym: "S1P4" EXACT [UniProtKB:O95977] synonym: "Sphingosine 1-phosphate receptor Edg-6" EXACT [UniProtKB:O95977] xref: EMBL:AAH14970.1 xref: EMBL:AAP84350.1 xref: EMBL:CAA04118.1 xref: UniProtKB:O95977 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022627 ! S1PR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity [Term] id: CCO:B0054814 name: MBD3_HUMAN def: "Methyl-CpG-binding domain protein 3" [UniProtKB:O95983] synonym: "Methyl-CpG-binding protein MBD3" EXACT [UniProtKB:O95983] xref: EMBL:AAC68876.1 xref: EMBL:AAC72104.1 xref: EMBL:AAH09372.1 xref: EMBL:AAH09438.1 xref: EMBL:AAH32443.1 xref: EMBL:AAH43619.1 xref: UniProtKB:O95983 xref: UniProtKB:Q6PIL9 xref: UniProtKB:Q6PJZ9 xref: UniProtKB:Q86XF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018579 ! MBD3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054815 name: TOP3B_HUMAN def: "DNA topoisomerase 3-beta-1" [UniProtKB:O95985] synonym: "DNA topoisomerase III beta-1" EXACT [UniProtKB:O95985] synonym: "EC 5.99.1.2" EXACT [UniProtKB:O95985] xref: EMBL:AAD01614.1 xref: EMBL:AAD15791.1 xref: EMBL:AAD29670.1 xref: EMBL:AAH02432.1 xref: EMBL:BAA20009.1 xref: EMBL:CAG30482.1 xref: UniProtKB:A0M8Q3 xref: UniProtKB:O95985 xref: UniProtKB:Q9BUP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020324 ! TOP3B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000419 ! DNA topoisomerase activity relationship: has_function CCO:F0000420 ! DNA topoisomerase type I activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0015006 ! chic2-top3b physical interaction relationship: participates_in CCO:I0015238 ! krtap4_12-top3b physical interaction relationship: participates_in CCO:I0017345 ! znf408-top3b physical interaction relationship: participates_in CCO:P0000632 ! DNA unwinding during replication [Term] id: CCO:B0054816 name: F107A_HUMAN def: "Protein FAM107A" [UniProtKB:O95990] synonym: "Down-regulated in renal cell carcinoma 1" EXACT [UniProtKB:O95990] synonym: "Protein TU3A" EXACT [UniProtKB:O95990] xref: EMBL:AAD16093.1 xref: EMBL:AAD16094.1 xref: EMBL:AAH10561.1 xref: EMBL:BAA82845.1 xref: EMBL:BAA83072.1 xref: EMBL:BAB70924.1 xref: EMBL:CAB43366.1 xref: UniProtKB:O95990 xref: UniProtKB:Q96NH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017751 ! FAM107A_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015061 ! drr1-efemp2 physical interaction relationship: participates_in CCO:I0015100 ! drr1-trim37 physical interaction relationship: participates_in CCO:I0015121 ! drr1-ldoc1 physical interaction relationship: participates_in CCO:I0015172 ! drr1-tada2l physical interaction relationship: participates_in CCO:I0015190 ! drr1-vim physical interaction relationship: participates_in CCO:I0015221 ! drr1-ushbp1 physical interaction relationship: participates_in CCO:I0015573 ! drr1-hook2 physical interaction relationship: participates_in CCO:I0015608 ! drr1-krt15 physical interaction relationship: participates_in CCO:I0015620 ! begain-drr1 physical interaction relationship: participates_in CCO:I0015664 ! drr1-krtap4_12 physical interaction relationship: participates_in CCO:I0015718 ! drr1-traf2 physical interaction relationship: participates_in CCO:I0015805 ! drr1-ndp52 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0054817 name: GAS8_HUMAN def: "Growth arrest-specific protein 8" [UniProtKB:O95995] synonym: "GAS-11" EXACT [UniProtKB:O95995] synonym: "GAS-8" EXACT [UniProtKB:O95995] synonym: "Growth arrest-specific protein 11" EXACT [UniProtKB:O95995] xref: EMBL:AAC69518.1 xref: EMBL:AAC69519.1 xref: EMBL:AAI04786.1 xref: EMBL:AAI12122.1 xref: UniProtKB:O95995 xref: UniProtKB:Q2M234 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017866 ! GAS8_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000629 ! microtubule-based flagellum relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0054818 name: GSUB_HUMAN def: "G-substrate" [UniProtKB:O96001] xref: EMBL:AAD12588.1 xref: EMBL:AAD13030.1 xref: EMBL:AAF03537.1 xref: EMBL:AAH28094.1 xref: UniProtKB:O96001 xref: UniProtKB:Q9UDQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018086 ! GSBS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0066638 ! GSUB_HUMAN-Phosphothreonine68 relationship: transforms_into CCO:B0066639 ! GSUB_HUMAN-Phosphothreonine119 [Term] id: CCO:B0054819 name: HAND1_HUMAN def: "Heart- and neural crest derivatives-expressed protein 1" [UniProtKB:O96004] synonym: "eHAND" EXACT [UniProtKB:O96004] synonym: "Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1" EXACT [UniProtKB:O96004] xref: EMBL:AAD19280.1 xref: EMBL:AAD19283.1 xref: EMBL:AAH21190.1 xref: UniProtKB:O96004 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018102 ! HAND1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054820 name: PX11B_HUMAN def: "Peroxisomal membrane protein 11B" [UniProtKB:O96011] synonym: "Peroxin-11B" EXACT [UniProtKB:O96011] synonym: "Peroxisomal biogenesis factor 11B" EXACT [UniProtKB:O96011] synonym: "PEX11beta" EXACT [UniProtKB:O96011] synonym: "Pex11pbeta" EXACT [UniProtKB:O96011] xref: EMBL:AAC78660.1 xref: EMBL:AAH11963.1 xref: EMBL:BAA34812.1 xref: EMBL:CAG46844.1 xref: UniProtKB:O96011 xref: UniProtKB:Q96ET2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019563 ! PEX11B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000361 ! integral to peroxisomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019379 ! pex19-pex11b-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054821 name: PAK4_HUMAN def: "Serine/threonine-protein kinase PAK 4" [UniProtKB:O96013] synonym: "EC 2.7.11.1" EXACT [UniProtKB:O96013] synonym: "p21-activated kinase 4" EXACT [UniProtKB:O96013] synonym: "PAK-4" EXACT [UniProtKB:O96013] xref: EMBL:AAD01210.1 xref: EMBL:AAH02921.1 xref: EMBL:AAH11368.1 xref: EMBL:AAH25282.1 xref: EMBL:AAH34511.1 xref: EMBL:BAA86456.1 xref: EMBL:BAC11166.1 xref: EMBL:CAA09820.1 xref: EMBL:CAD38914.2 xref: UniProtKB:O96013 xref: UniProtKB:Q8N4E1 xref: UniProtKB:Q8NCH5 xref: UniProtKB:Q8NDE3 xref: UniProtKB:Q9BU33 xref: UniProtKB:Q9ULS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019294 ! PAK4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019779 ! pak4-dlst physical interaction relationship: participates_in CCO:I0020616 ! pak4-p66alpha physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069067 ! PAK4_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0069068 ! PAK4_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0069069 ! PAK4_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0069070 ! PAK4_HUMAN-Phosphoserine167 relationship: transforms_into CCO:B0069071 ! PAK4_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0069072 ! PAK4_HUMAN-Phosphothreonine207 relationship: transforms_into CCO:B0069073 ! PAK4_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0069074 ! PAK4_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0069075 ! PAK4_HUMAN-Phosphoserine474 [Term] id: CCO:B0054822 name: WNT11_HUMAN def: "Protein Wnt-11 precursor" [UniProtKB:O96014] xref: EMBL:AAH74790.1 xref: EMBL:AAH74791.1 xref: EMBL:AAI13387.1 xref: EMBL:AAI13389.1 xref: EMBL:BAB72099.1 xref: EMBL:CAA73223.1 xref: EMBL:CAA74159.1 xref: UniProtKB:O96014 xref: UniProtKB:Q14DE8 xref: UniProtKB:Q8WZ98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020483 ! WNT11_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054823 name: NSD2_HUMAN def: "Probable histone-lysine N-methyltransferase NSD2" [UniProtKB:O96028] synonym: "EC 2.1.1.43" EXACT [UniProtKB:O96028] synonym: "Multiple myeloma SET domain-containing protein" EXACT [UniProtKB:O96028] synonym: "Nuclear SET domain-containing protein 2" EXACT [UniProtKB:O96028] synonym: "Protein trithorax-5" EXACT [UniProtKB:O96028] synonym: "Wolf-Hirschhorn syndrome candidate 1 protein" EXACT [UniProtKB:O96028] xref: EMBL:AAC24150.1 xref: EMBL:AAC24151.1 xref: EMBL:AAD19343.1 xref: EMBL:AAD19344.1 xref: EMBL:AAD19345.1 xref: EMBL:AAD19346.1 xref: EMBL:AAD21770.1 xref: EMBL:AAD21771.1 xref: EMBL:AAF23369.1 xref: EMBL:AAF23370.1 xref: EMBL:AAH52254.1 xref: EMBL:AAH70176.1 xref: EMBL:AAH94825.2 xref: EMBL:AAK00344.1 xref: EMBL:AAU09264.1 xref: EMBL:BAA83042.2 xref: EMBL:CAB45386.1 xref: UniProtKB:O96028 xref: UniProtKB:O96031 xref: UniProtKB:Q4VBY8 xref: UniProtKB:Q672J1 xref: UniProtKB:Q6IS00 xref: UniProtKB:Q86V01 xref: UniProtKB:Q9BZB4 xref: UniProtKB:Q9UI92 xref: UniProtKB:Q9UPR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018874 ! WHSC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068863 ! NSD2_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0068864 ! NSD2_HUMAN-Phosphothreonine544 [Term] id: CCO:B0054824 name: DHE3_HUMAN def: "Glutamate dehydrogenase 1, mitochondrial precursor" [UniProtKB:P00367] synonym: "EC 1.4.1.3" EXACT [UniProtKB:P00367] synonym: "GDH" EXACT [UniProtKB:P00367] xref: EMBL:AAA52523.1 xref: EMBL:AAA52525.1 xref: EMBL:AAA52526.1 xref: EMBL:AAH40132.1 xref: EMBL:AAI12947.1 xref: EMBL:CAA30521.1 xref: EMBL:CAA30598.1 xref: EMBL:CAA46994.2 xref: EMBL:CAA47830.1 xref: EMBL:CAI17120.1 xref: UniProtKB:P00367 xref: UniProtKB:Q5TBU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017575 ! GLUD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016608 ! map3k1-glud1 physical interaction relationship: participates_in CCO:I0016845 ! map3k14-glud1 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0064756 ! DHE3_HUMAN-N6-acetyllysine84 relationship: transforms_into CCO:B0064757 ! DHE3_HUMAN-Phosphotyrosine135 relationship: transforms_into CCO:B0064758 ! DHE3_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0064759 ! DHE3_HUMAN-N6-acetyllysine503 relationship: transforms_into CCO:B0064760 ! DHE3_HUMAN-Phosphotyrosine512 relationship: transforms_into CCO:B0064761 ! DHE3_HUMAN-N6-acetyllysine527 [Term] id: CCO:B0054825 name: LALBA_HUMAN def: "Alpha-lactalbumin precursor" [UniProtKB:P00709] synonym: "Lactose synthase B protein" EXACT [UniProtKB:P00709] synonym: "Lysozyme-like protein 7" EXACT [UniProtKB:P00709] xref: EMBL:AAA60345.1 xref: EMBL:AAH69103.1 xref: EMBL:AAI12317.1 xref: EMBL:AAI12319.1 xref: EMBL:BAC06860.1 xref: EMBL:CAA28799.1 xref: EMBL:CAA28800.1 xref: EMBL:CAG46784.1 xref: EMBL:CAG46814.1 xref: EMBL:EAW57990.1 xref: UniProtKB:P00709 xref: UniProtKB:Q6FGX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018451 ! LALBA_human relationship: has_function CCO:F0000861 ! lactose synthase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054826 name: PLMN_HUMAN def: "Plasminogen precursor" [UniProtKB:P00747] synonym: "EC 3.4.21.7" EXACT [UniProtKB:P00747] xref: EMBL:AAA36451.1 xref: EMBL:AAA60113.1 xref: EMBL:AAA60124.1 xref: EMBL:AAH60513.1 xref: EMBL:AAN85555.1 xref: EMBL:CAA28831.1 xref: EMBL:CAI22908.1 xref: UniProtKB:P00747 xref: UniProtKB:Q15146 xref: UniProtKB:Q5TEH4 xref: UniProtKB:Q6PA00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019444 ! PLG_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000710 ! plasmin activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005523 ! apolipoprotein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002238 ! negative regulation of blood vessel endothelial cell migration relationship: transforms_into CCO:B0069418 ! PLMN_HUMAN-Phosphoserine597 [Term] id: CCO:B0054827 name: UROK_HUMAN def: "Urokinase-type plasminogen activator precursor" [UniProtKB:P00749] synonym: "EC 3.4.21.73" EXACT [UniProtKB:P00749] synonym: "U-plasminogen activator" EXACT [UniProtKB:P00749] synonym: "uPA" EXACT [UniProtKB:P00749] xref: EMBL:AAA61252.1 xref: EMBL:AAA61253.1 xref: EMBL:AAC97138.1 xref: EMBL:AAH13575.1 xref: EMBL:AAK53822.1 xref: EMBL:BAA00175.1 xref: EMBL:BAA01919.1 xref: EMBL:CAA01390.1 xref: EMBL:CAA01559.1 xref: EMBL:CAA26268.1 xref: EMBL:CAA26535.1 xref: UniProtKB:P00749 xref: UniProtKB:Q15844 xref: UniProtKB:Q16618 xref: UniProtKB:Q969W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020418 ! PLAU_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001793 ! plasminogen activator activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071739 ! UROK_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0071740 ! UROK_HUMAN-Phosphoserine323 [Term] id: CCO:B0054828 name: RENI_HUMAN def: "Renin precursor" [UniProtKB:P00797] synonym: "Angiotensinogenase" EXACT [UniProtKB:P00797] synonym: "EC 3.4.23.15" EXACT [UniProtKB:P00797] xref: EMBL:AAA60262.1 xref: EMBL:AAA60263.1 xref: EMBL:AAA60363.1 xref: EMBL:AAA60364.1 xref: EMBL:AAA60365.1 xref: EMBL:AAD03461.1 xref: EMBL:AAH33474.1 xref: EMBL:AAH47752.1 xref: EMBL:AAR03502.1 xref: EMBL:CAH71224.1 xref: EMBL:CAI16594.1 xref: UniProtKB:P00797 xref: UniProtKB:Q6T5C2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019670 ! REN_human relationship: has_function CCO:F0000659 ! aspartic-type endopeptidase activity relationship: has_function CCO:F0000663 ! pepsin A activity relationship: has_function CCO:F0000664 ! renin activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020050 ! kctd15-ren physical interaction relationship: participates_in CCO:P0002209 ! regulation of MAPKKK cascade [Term] id: CCO:B0054829 name: ADA_HUMAN def: "Adenosine deaminase" [UniProtKB:P00813] synonym: "Adenosine aminohydrolase" EXACT [UniProtKB:P00813] synonym: "EC 3.5.4.4" EXACT [UniProtKB:P00813] xref: EMBL:AAA78791.1 xref: EMBL:AAH07678.1 xref: EMBL:AAH40226.1 xref: EMBL:BAD97117.1 xref: EMBL:CAA26130.1 xref: EMBL:CAA26734.1 xref: EMBL:CAB09782.2 xref: EMBL:CAH73885.1 xref: UniProtKB:P00813 xref: UniProtKB:Q53F92 xref: UniProtKB:Q6LA59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016909 ! ADA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001848 ! regulation of cell-cell adhesion mediated by integrin relationship: participates_in CCO:P0003272 ! negative regulation of adenosine receptor signaling pathway relationship: transforms_into CCO:B0065403 ! ADA_HUMAN-N-acetylalanine2 [Term] id: CCO:B0054830 name: CO5_HUMAN def: "Complement C5 precursor" [UniProtKB:P01031] synonym: "C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4" EXACT [UniProtKB:P01031] xref: EMBL:AAA51856.1 xref: EMBL:AAA51925.1 xref: EMBL:AAI13739.1 xref: EMBL:AAI13741.1 xref: EMBL:ABD48959.1 xref: EMBL:EAW87480.1 xref: UniProtKB:P01031 xref: UniProtKB:Q14CJ0 xref: UniProtKB:Q27I61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017425 ! C5_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000204 ! membrane attack complex relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054831 name: TIMP1_HUMAN def: "Metalloproteinase inhibitor 1 precursor" [UniProtKB:P01033] synonym: "Collagenase inhibitor" EXACT [UniProtKB:P01033] synonym: "EPA" EXACT [UniProtKB:P01033] synonym: "Erythroid-potentiating activity" EXACT [UniProtKB:P01033] synonym: "Fibroblast collagenase inhibitor" EXACT [UniProtKB:P01033] synonym: "TIMP-1" EXACT [UniProtKB:P01033] synonym: "Tissue inhibitor of metalloproteinases" EXACT [UniProtKB:P01033] xref: EMBL:AAA52436.1 xref: EMBL:AAA63234.1 xref: EMBL:AAA75558.1 xref: EMBL:AAD14009.1 xref: EMBL:AAH00866.1 xref: EMBL:BAA01913.1 xref: EMBL:CAA26443.1 xref: EMBL:CAA26902.1 xref: UniProtKB:P01033 xref: UniProtKB:Q14252 xref: UniProtKB:Q9UCU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020272 ! TIMP1_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001771 ! metalloendopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:I0019629 ! timp1-ech1 physical interaction relationship: participates_in CCO:I0019630 ! timp1-eef1b2 physical interaction relationship: participates_in CCO:I0019631 ! timp1-sumo2 physical interaction relationship: participates_in CCO:I0019854 ! timp1-recql5 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0003014 ! negative regulation of membrane protein ectodomain proteolysis [Term] id: CCO:B0054832 name: KNG1_HUMAN def: "Kininogen-1 precursor" [UniProtKB:P01042] synonym: "Alpha-2-thiol proteinase inhibitor" EXACT [UniProtKB:P01042] xref: EMBL:AAA35497.1 xref: EMBL:AAB59550.1 xref: EMBL:AAB59551.1 xref: EMBL:AAO61092.1 xref: UniProtKB:P01042 xref: UniProtKB:P01043 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018431 ! KNG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0067387 ! KNG1_HUMAN-acid19 relationship: transforms_into CCO:B0067388 ! KNG1_HUMAN-4-hydroxyproline383 [Term] id: CCO:B0054833 name: FOS_HUMAN def: "Proto-oncogene protein c-fos" [UniProtKB:P01100] synonym: "Cellular oncogene fos" EXACT [UniProtKB:P01100] synonym: "G0/G1 switch regulatory protein 7" EXACT [UniProtKB:P01100] xref: EMBL:AAA52471.1 xref: EMBL:AAB20306.1 xref: EMBL:AAC98315.1 xref: EMBL:AAH04490.1 xref: EMBL:AAO21129.1 xref: EMBL:CAA24756.1 xref: UniProtKB:P01100 xref: UniProtKB:P18849 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017821 ! FOS_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000646 ! DNA methylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054834 name: NGF_HUMAN def: "Beta-nerve growth factor precursor" [UniProtKB:P01138] synonym: "Beta-NGF" EXACT [UniProtKB:P01138] xref: EMBL:AAA59931.1 xref: EMBL:AAD55975.1 xref: EMBL:AAH32517.2 xref: EMBL:AAL05874.1 xref: EMBL:AAV38538.1 xref: EMBL:BAA90437.1 xref: EMBL:CAA24755.1 xref: EMBL:CAA36832.1 xref: EMBL:CAB75625.1 xref: EMBL:CAG46653.1 xref: UniProtKB:P01138 xref: UniProtKB:Q6FHA0 xref: UniProtKB:Q96P60 xref: UniProtKB:Q9P2Q8 xref: UniProtKB:Q9UKL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018785 ! NGF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018114 ! ngfb-ntrk1-1 direct interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation relationship: participates_in CCO:P0002548 ! positive regulation of axon extension relationship: participates_in CCO:P0002749 ! regulation of neurotransmitter secretion relationship: transforms_into CCO:B0068706 ! NGF_HUMAN-Phosphoserine84 [Term] id: CCO:B0054835 name: GON1_HUMAN def: "Progonadoliberin-1 precursor" [UniProtKB:P01148] synonym: "Progonadoliberin I" EXACT [UniProtKB:P01148] xref: EMBL:AAA35916.1 xref: EMBL:AAI26438.1 xref: EMBL:AAI26464.1 xref: EMBL:CAA25526.1 xref: EMBL:CAA33285.1 xref: UniProtKB:A0AVP0 xref: UniProtKB:P01148 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017949 ! GNRH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0066512 ! GON1_HUMAN-Pyrrolidone carboxylic acid24 relationship: transforms_into CCO:B0066513 ! GON1_HUMAN-Glycine amide33 [Term] id: CCO:B0054836 name: PENK_HUMAN def: "Proenkephalin A precursor" [UniProtKB:P01210] xref: EMBL:AAB59409.1 xref: EMBL:AAH32505.1 xref: EMBL:CAA23767.1 xref: UniProtKB:P01210 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019364 ! PENK_human relationship: has_function CCO:F0000130 ! opioid peptide activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054837 name: PDYN_HUMAN def: "Beta-neoendorphin-dynorphin precursor" [UniProtKB:P01213] synonym: "Preprodynorphin" EXACT [UniProtKB:P01213] synonym: "Proenkephalin B" EXACT [UniProtKB:P01213] xref: EMBL:AAA58456.2 xref: EMBL:AAH26334.1 xref: EMBL:CAA24999.1 xref: EMBL:CAB38875.1 xref: UniProtKB:P01213 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019351 ! PDYN_human relationship: has_function CCO:F0000130 ! opioid peptide activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054838 name: TSHB_HUMAN def: "Thyrotropin subunit beta precursor" [UniProtKB:P01222] synonym: "Thyroid-stimulating hormone subunit beta" EXACT [UniProtKB:P01222] synonym: "Thyrotropin alfa" EXACT [UniProtKB:P01222] synonym: "Thyrotropin beta chain" EXACT [UniProtKB:P01222] synonym: "TSH-B" EXACT [UniProtKB:P01222] synonym: "TSH-beta" EXACT [UniProtKB:P01222] xref: EMBL:AAA36782.1 xref: EMBL:AAA61235.1 xref: EMBL:AAB05845.1 xref: EMBL:AAB30828.2 xref: EMBL:AAH69298.1 xref: EMBL:CAA26618.1 xref: EMBL:CAA26619.1 xref: UniProtKB:P01222 xref: UniProtKB:Q16163 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020372 ! TSHB_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054839 name: FSHB_HUMAN def: "Follitropin subunit beta precursor" [UniProtKB:P01225] synonym: "Follicle-stimulating hormone beta subunit" EXACT [UniProtKB:P01225] synonym: "Follitropin beta chain" EXACT [UniProtKB:P01225] synonym: "FSH-B" EXACT [UniProtKB:P01225] synonym: "FSH-beta" EXACT [UniProtKB:P01225] xref: EMBL:AAA52470.1 xref: EMBL:AAA52476.1 xref: EMBL:AAB02868.1 xref: EMBL:AAI13489.1 xref: EMBL:AAI13491.1 xref: UniProtKB:P01225 xref: UniProtKB:Q14D61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017840 ! FSHB_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0003466 ! follicle-stimulating hormone activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0016197 ! cga-fshb-1 direct interaction relationship: participates_in CCO:I0018403 ! cga-fshb-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003228 ! Sertoli cell proliferation [Term] id: CCO:B0054840 name: LSHB_HUMAN def: "Lutropin subunit beta precursor" [UniProtKB:P01229] synonym: "LH-B" EXACT [UniProtKB:P01229] synonym: "LSH-B" EXACT [UniProtKB:P01229] synonym: "LSH-beta" EXACT [UniProtKB:P01229] synonym: "Luteinizing hormone subunit beta" EXACT [UniProtKB:P01229] synonym: "Lutropin beta chain" EXACT [UniProtKB:P01229] xref: EMBL:AAD14960.1 xref: EMBL:CAA25067.1 xref: UniProtKB:P01229 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018524 ! LHB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054841 name: CGHB_HUMAN def: "Choriogonadotropin subunit beta precursor" [UniProtKB:P01233] synonym: "CG-beta" EXACT [UniProtKB:P01233] synonym: "Chorionic gonadotrophin chain beta" EXACT [UniProtKB:P01233] xref: EMBL:AAA52005.1 xref: EMBL:AAA52008.1 xref: EMBL:AAA52009.1 xref: EMBL:AAA53287.1 xref: EMBL:AAA53288.1 xref: EMBL:AAA96690.1 xref: EMBL:AAH06290.1 xref: EMBL:AAH22796.1 xref: EMBL:AAH30994.1 xref: EMBL:AAH41054.1 xref: EMBL:AAH51378.1 xref: EMBL:AAH69526.1 xref: EMBL:AAI03970.1 xref: EMBL:AAI03971.1 xref: EMBL:AAI03972.1 xref: EMBL:AAI06060.1 xref: EMBL:AAL69704.1 xref: EMBL:AAL69705.1 xref: EMBL:AAL69706.1 xref: EMBL:AAL69707.1 xref: EMBL:AAL69708.1 xref: EMBL:AAL69709.1 xref: EMBL:AAP35536.1 xref: EMBL:CAA25068.1 xref: EMBL:CAA25069.1 xref: UniProtKB:P01233 xref: UniProtKB:Q13991 xref: UniProtKB:Q14000 xref: UniProtKB:Q3SY41 xref: UniProtKB:Q8WTT5 xref: UniProtKB:Q8WXL1 xref: UniProtKB:Q8WXL2 xref: UniProtKB:Q8WXL3 xref: UniProtKB:Q8WXL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017344 ! CGB_human relationship: encoded_by CCO:G0017345 ! CGB5_human relationship: encoded_by CCO:G0017346 ! CGB7_human relationship: encoded_by CCO:G0017347 ! CGB8_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054842 name: PRL_HUMAN def: "Prolactin precursor" [UniProtKB:P01236] synonym: "PRL" EXACT [UniProtKB:P01236] xref: EMBL:AAA60173.1 xref: EMBL:AAB70858.1 xref: EMBL:AAH15850.1 xref: EMBL:BAA00312.1 xref: EMBL:CAA23829.1 xref: EMBL:CAA25214.1 xref: EMBL:CAA38263.1 xref: EMBL:CAA38264.1 xref: UniProtKB:P01236 xref: UniProtKB:Q15199 xref: UniProtKB:Q92996 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019513 ! PRL_human relationship: has_function CCO:F0001450 ! prolactin receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054843 name: SOMA_HUMAN def: "Somatotropin precursor" [UniProtKB:P01241] synonym: "GH" EXACT [UniProtKB:P01241] synonym: "GH-N" EXACT [UniProtKB:P01241] synonym: "Growth hormone" EXACT [UniProtKB:P01241] synonym: "Growth hormone 1" EXACT [UniProtKB:P01241] synonym: "Pituitary growth hormone" EXACT [UniProtKB:P01241] xref: EMBL:AAA52549.1 xref: EMBL:AAA52554.1 xref: EMBL:AAA98618.1 xref: EMBL:AAD48584.1 xref: EMBL:AAG09699.1 xref: EMBL:AAH62475.1 xref: EMBL:AAH75012.1 xref: EMBL:AAH75013.1 xref: EMBL:AAH90045.1 xref: EMBL:CAA00065.1 xref: EMBL:CAA01057.1 xref: EMBL:CAA23778.1 xref: EMBL:CAA23779.1 xref: UniProtKB:P01241 xref: UniProtKB:Q14405 xref: UniProtKB:Q16631 xref: UniProtKB:Q5EB53 xref: UniProtKB:Q9HBZ1 xref: UniProtKB:Q9UMJ7 xref: UniProtKB:Q9UNL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019981 ! GH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017812 ! gh1-prlr-1 direct interaction relationship: participates_in CCO:I0019182 ! gh1-ghr-3 direct interaction relationship: participates_in CCO:I0019320 ! gh1-ghr-1 direct interaction relationship: participates_in CCO:I0019321 ! gh1-ghr-2 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070721 ! SOMA_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0070722 ! SOMA_HUMAN-glutamine163 relationship: transforms_into CCO:B0070723 ! SOMA_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0070724 ! SOMA_HUMAN-asparagine178 [Term] id: CCO:B0054844 name: CSH_HUMAN def: "Chorionic somatomammotropin hormone precursor" [UniProtKB:P01243] synonym: "Choriomammotropin" EXACT [UniProtKB:P01243] synonym: "Lactogen" EXACT [UniProtKB:P01243] xref: EMBL:AAA52115.1 xref: EMBL:AAA52116.1 xref: EMBL:AAA52551.1 xref: EMBL:AAA52553.1 xref: EMBL:AAA98621.1 xref: EMBL:AAA98747.1 xref: EMBL:AAH02717.1 xref: EMBL:AAH05921.1 xref: EMBL:AAH20756.1 xref: EMBL:AAH22044.1 xref: EMBL:AAH35965.1 xref: EMBL:AAH62775.1 xref: EMBL:AAP35572.1 xref: EMBL:CAA23836.1 xref: UniProtKB:P01243 xref: UniProtKB:Q14407 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017477 ! CSH1_human relationship: encoded_by CCO:G0017478 ! CSH2_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054845 name: CALC_HUMAN def: "Calcitonin precursor" [UniProtKB:P01258] xref: EMBL:AAA35501.1 xref: EMBL:AAA51913.1 xref: EMBL:AAA52124.1 xref: EMBL:AAA58403.1 xref: EMBL:AAH69684.1 xref: EMBL:AAH69704.1 xref: EMBL:AAH69760.1 xref: EMBL:AAH69778.1 xref: EMBL:AAH93753.1 xref: EMBL:AAI01600.1 xref: EMBL:AAY68212.1 xref: EMBL:CAA25103.1 xref: EMBL:CAA26189.1 xref: EMBL:CAA27299.1 xref: EMBL:CAA34070.1 xref: UniProtKB:P01258 xref: UniProtKB:Q13935 xref: UniProtKB:Q13937 xref: UniProtKB:Q52LX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017215 ! CALCA_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0004729 ! calcitonin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0001727 ! terminal button relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0003100 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: transforms_into CCO:B0064056 ! CALC_HUMAN-Proline amide116 [Term] id: CCO:B0054846 name: THYG_HUMAN def: "Thyroglobulin precursor" [UniProtKB:P01266] synonym: "Tg" EXACT [UniProtKB:P01266] xref: EMBL:AAB22685.1 xref: EMBL:AAC51924.1 xref: EMBL:AAC95473.1 xref: EMBL:AAD50912.2 xref: EMBL:AAD51647.1 xref: EMBL:CAA26089.1 xref: EMBL:CAA26527.1 xref: EMBL:CAA29104.1 xref: EMBL:CAA29454.1 xref: EMBL:CAA29455.1 xref: EMBL:CAA29456.1 xref: UniProtKB:O15274 xref: UniProtKB:O43899 xref: UniProtKB:P01266 xref: UniProtKB:Q15593 xref: UniProtKB:Q15948 xref: UniProtKB:Q9NYR1 xref: UniProtKB:Q9NYR2 xref: UniProtKB:Q9UMZ0 xref: UniProtKB:Q9UNY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020257 ! TG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071388 ! THYG_HUMAN-Sulfotyrosine24 relationship: transforms_into CCO:B0071389 ! THYG_HUMAN-Thyroxine24 relationship: transforms_into CCO:B0071390 ! THYG_HUMAN-Thyroxine1310 relationship: transforms_into CCO:B0071391 ! THYG_HUMAN-Thyroxine2573 relationship: transforms_into CCO:B0071392 ! THYG_HUMAN-Thyroxine2587 relationship: transforms_into CCO:B0071393 ! THYG_HUMAN-Triiodothyronine2766 [Term] id: CCO:B0054847 name: PTHY_HUMAN def: "Parathyroid hormone precursor" [UniProtKB:P01270] synonym: "Parathormone" EXACT [UniProtKB:P01270] synonym: "Parathyrin" EXACT [UniProtKB:P01270] synonym: "PTH" EXACT [UniProtKB:P01270] xref: EMBL:AAA60215.1 xref: EMBL:AAH96142.1 xref: EMBL:AAH96143.1 xref: EMBL:AAH96144.1 xref: EMBL:AAH96145.1 xref: EMBL:CAA23843.1 xref: UniProtKB:P01270 xref: UniProtKB:Q4VB48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019544 ! PTH_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0004867 ! parathyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0020130 ! pth-bat3 physical interaction relationship: participates_in CCO:I0020131 ! pth-fez1 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000835 ! induction of apoptosis by hormones [Term] id: CCO:B0054848 name: GLUC_HUMAN def: "Glucagon precursor" [UniProtKB:P01275] xref: EMBL:AAA52567.1 xref: EMBL:AAH05278.1 xref: EMBL:AAP35459.1 xref: EMBL:AAY24204.1 xref: EMBL:CAA24759.1 xref: EMBL:CAA27627.1 xref: UniProtKB:A6NN65 xref: UniProtKB:P01275 xref: UniProtKB:Q53TP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017935 ! GCG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066471 ! GLUC_HUMAN-Arginine amide127 [Term] id: CCO:B0054849 name: VIP_HUMAN def: "VIP peptides precursor" [UniProtKB:P01282] xref: EMBL:AAA61284.1 xref: EMBL:AAA61285.1 xref: EMBL:AAA61286.1 xref: EMBL:AAA61287.1 xref: EMBL:AAA61288.1 xref: EMBL:AAA61289.1 xref: EMBL:AAA63268.1 xref: EMBL:AAA69515.1 xref: EMBL:AAH09794.1 xref: EMBL:CAI21764.1 xref: EMBL:CAI21765.1 xref: UniProtKB:P01282 xref: UniProtKB:Q5TCY8 xref: UniProtKB:Q5TCY9 xref: UniProtKB:Q96QK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020452 ! VIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015722 ! meox2-vip physical interaction relationship: participates_in CCO:I0017541 ! vip-ubqln4 physical interaction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0071810 ! VIP_HUMAN-Methionine amide107 relationship: transforms_into CCO:B0071811 ! VIP_HUMAN-Asparagine amide152 [Term] id: CCO:B0054850 name: SLIB_HUMAN def: "Somatoliberin precursor" [UniProtKB:P01286] synonym: "GHRH" EXACT [UniProtKB:P01286] synonym: "GRF" EXACT [UniProtKB:P01286] synonym: "Growth hormone-releasing factor" EXACT [UniProtKB:P01286] synonym: "Growth hormone-releasing hormone" EXACT [UniProtKB:P01286] synonym: "Sermorelin" EXACT [UniProtKB:P01286] synonym: "Somatocrinin" EXACT [UniProtKB:P01286] synonym: "Somatorelin" EXACT [UniProtKB:P01286] xref: EMBL:AAA52608.1 xref: EMBL:AAA52609.1 xref: EMBL:AAH98109.1 xref: EMBL:AAH99727.1 xref: EMBL:CAA24955.1 xref: EMBL:CAA24956.1 xref: EMBL:CAB41762.2 xref: EMBL:CAI42673.1 xref: UniProtKB:P01286 xref: UniProtKB:Q5JYR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019933 ! GHRH_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0004783 ! growth hormone-releasing hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0003251 ! positive regulation of growth hormone secretion relationship: transforms_into CCO:B0070576 ! SLIB_HUMAN-Leucine amide75 [Term] id: CCO:B0054851 name: NPY_HUMAN def: "Neuropeptide Y precursor" [UniProtKB:P01303] xref: EMBL:AAA59944.1 xref: EMBL:AAA59945.1 xref: EMBL:AAA59946.1 xref: EMBL:AAH29497.1 xref: EMBL:AAQ96843.1 xref: UniProtKB:P01303 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018846 ! NPY_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0068816 ! NPY_HUMAN-Tyrosine amide64 [Term] id: CCO:B0054852 name: INS_HUMAN def: "Insulin precursor" [UniProtKB:P01308] xref: EMBL:AAA59172.1 xref: EMBL:AAA59173.1 xref: EMBL:AAA59179.1 xref: EMBL:AAH05255.1 xref: EMBL:AAN39451.1 xref: EMBL:AAP35454.1 xref: EMBL:AAW83741.1 xref: EMBL:CAA08766.1 xref: EMBL:CAA23828.1 xref: EMBL:CAA49913.1 xref: EMBL:EAX02488.1 xref: UniProtKB:P01308 xref: UniProtKB:Q5EEX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018295 ! INS_human relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000668 ! regulation of amino acid metabolic process relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001084 ! phosphoinositide 3-kinase cascade relationship: participates_in CCO:P0001574 ! positive regulation of cellular protein metabolic process relationship: participates_in CCO:P0001644 ! regulation of gene-specific transcription relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002566 ! negative regulation of glycogen catabolic process relationship: participates_in CCO:P0002569 ! positive regulation of glycolysis relationship: participates_in CCO:P0002578 ! negative regulation of proteolysis relationship: participates_in CCO:P0002615 ! negative regulation of fatty acid metabolic process relationship: participates_in CCO:P0002706 ! positive regulation of insulin receptor signaling pathway [Term] id: CCO:B0054853 name: IGF1A_HUMAN def: "Insulin-like growth factor IA precursor" [UniProtKB:P01343] synonym: "IGF-IA" EXACT [UniProtKB:P01343] synonym: "Mechano growth factor" EXACT [UniProtKB:P01343] synonym: "MGF" EXACT [UniProtKB:P01343] synonym: "Somatomedin-C" EXACT [UniProtKB:P01343] xref: EMBL:AAA52538.1 xref: EMBL:AAA52787.1 xref: EMBL:AAO74829.1 xref: EMBL:CAA24998.1 xref: EMBL:CAA27152.1 xref: EMBL:CAA27153.1 xref: EMBL:CAA27154.1 xref: EMBL:CAA27250.1 xref: EMBL:CAA40092.1 xref: EMBL:CAA40342.1 xref: UniProtKB:P01343 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014356 ! IGF1_human relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001799 ! regulation of steroid hormone receptor signaling pathway [Term] id: CCO:B0054854 name: GAST_HUMAN def: "Gastrin precursor" [UniProtKB:P01350] xref: EMBL:AAA52520.1 xref: EMBL:AAB59533.1 xref: EMBL:AAH69724.1 xref: EMBL:AAH69762.1 xref: EMBL:CAA23769.1 xref: EMBL:CAA25005.1 xref: EMBL:CAA25006.1 xref: EMBL:CAA25007.1 xref: UniProtKB:P01350 xref: UniProtKB:P78463 xref: UniProtKB:P78464 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017868 ! GAST_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066383 ! GAST_HUMAN-acid59 relationship: transforms_into CCO:B0066384 ! GAST_HUMAN-acid76 relationship: transforms_into CCO:B0066385 ! GAST_HUMAN-Sulfotyrosine87 relationship: transforms_into CCO:B0066386 ! GAST_HUMAN-Phenylalanine amide92 relationship: transforms_into CCO:B0066387 ! GAST_HUMAN-Phosphoserine96 [Term] id: CCO:B0054855 name: EPO_HUMAN def: "Erythropoietin precursor" [UniProtKB:P01588] synonym: "Epoetin" EXACT [UniProtKB:P01588] xref: EMBL:AAA52400.1 xref: EMBL:AAC78791.1 xref: EMBL:AAD13964.1 xref: EMBL:AAF17572.1 xref: EMBL:AAF23132.1 xref: EMBL:AAF23133.1 xref: EMBL:AAF23134.1 xref: EMBL:AAH93628.1 xref: EMBL:AAI11938.1 xref: EMBL:AAP22357.1 xref: EMBL:CAA26094.1 xref: EMBL:CAA26095.1 xref: UniProtKB:P01588 xref: UniProtKB:Q2M2L6 xref: UniProtKB:Q549U2 xref: UniProtKB:Q9UDZ0 xref: UniProtKB:Q9UEZ5 xref: UniProtKB:Q9UHA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017722 ! EPO_human relationship: has_function CCO:F0001430 ! erythropoietin receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0018740 ! epo-epor-1 direct interaction relationship: participates_in CCO:I0018741 ! epo-epor-2 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002088 ! positive regulation of tyrosine phosphorylation of Stat5 protein relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002699 ! positive regulation of Ras protein signal transduction [Term] id: CCO:B0054856 name: CD8A_HUMAN def: "T-cell surface glycoprotein CD8 alpha chain precursor" [UniProtKB:P01732] synonym: "CD8a antigen" EXACT [UniProtKB:P01732] synonym: "T-lymphocyte differentiation antigen T8/Leu-2" EXACT [UniProtKB:P01732] xref: EMBL:AAA59674.1 xref: EMBL:AAA61133.1 xref: EMBL:AAA79217.1 xref: EMBL:AAA79218.1 xref: EMBL:AAB04637.1 xref: UniProtKB:P01732 xref: UniProtKB:Q13970 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017314 ! CD8A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0005648 ! MHC class I protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0054858 name: 2B32_HUMAN def: "HLA class II histocompatibility antigen, DRB3-2 beta chain precursor" [UniProtKB:P01913] synonym: "MHC class I antigen DRB3*2" EXACT [UniProtKB:P01913] xref: EMBL:AAA59804.1 xref: EMBL:AAB63531.1 xref: EMBL:AAD45286.1 xref: EMBL:AAD53911.1 xref: EMBL:AAF26358.1 xref: EMBL:AAF26359.1 xref: EMBL:AAF67837.1 xref: EMBL:CAA00596.1 xref: EMBL:CAA04629.1 xref: EMBL:CAA23781.1 xref: EMBL:CAA65066.1 xref: EMBL:CAA71253.1 xref: UniProtKB:O78049 xref: UniProtKB:P01913 xref: UniProtKB:P79663 xref: UniProtKB:Q29721 xref: UniProtKB:Q29809 xref: UniProtKB:Q30144 xref: UniProtKB:Q9MYA4 xref: UniProtKB:Q9MYH3 xref: UniProtKB:Q9MYH4 xref: UniProtKB:Q9TPB5 xref: UniProtKB:Q9TQ21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011859 ! HLA-DRB3_human relationship: has_function CCO:F0004979 ! MHC class II receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001670 ! MHC class II protein complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054859 name: CO3A1_HUMAN def: "Collagen alpha-1(III) chain precursor" [UniProtKB:P02461] xref: EMBL:AAA52003.1 xref: EMBL:AAA52004.1 xref: EMBL:AAA52040.1 xref: EMBL:AAA52041.1 xref: EMBL:AAB35615.1 xref: EMBL:AAB59383.1 xref: EMBL:AAD13937.1 xref: EMBL:AAH28178.1 xref: EMBL:AAL13167.1 xref: EMBL:AAY24164.1 xref: EMBL:CAA25821.1 xref: EMBL:CAA25879.1 xref: EMBL:CAA29886.1 xref: EMBL:CAA30229.1 xref: EMBL:CAA32583.1 xref: EMBL:CAA33387.1 xref: UniProtKB:P02461 xref: UniProtKB:P78429 xref: UniProtKB:Q15112 xref: UniProtKB:Q16403 xref: UniProtKB:Q53S91 xref: UniProtKB:Q541P8 xref: UniProtKB:Q6LDB3 xref: UniProtKB:Q6LDJ2 xref: UniProtKB:Q6LDJ3 xref: UniProtKB:Q7KZ56 xref: UniProtKB:Q8N6U4 xref: UniProtKB:Q9UC88 xref: UniProtKB:Q9UC89 xref: UniProtKB:Q9UC90 xref: UniProtKB:Q9UC91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017422 ! COL3A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0064436 ! CO3A1_HUMAN-5-hydroxylysine263 relationship: transforms_into CCO:B0064437 ! CO3A1_HUMAN-5-hydroxylysine284 relationship: transforms_into CCO:B0064438 ! CO3A1_HUMAN-5-hydroxylysine860 relationship: transforms_into CCO:B0064439 ! CO3A1_HUMAN-5-hydroxylysine977 relationship: transforms_into CCO:B0064440 ! CO3A1_HUMAN-5-hydroxylysine1094 relationship: transforms_into CCO:B0064441 ! CO3A1_HUMAN-5-hydroxylysine1106 relationship: transforms_into CCO:B0064442 ! CO3A1_HUMAN-Phosphotyrosine1378 relationship: transforms_into CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 [Term] id: CCO:B0054860 name: CRYAA_HUMAN def: "Alpha-crystallin A chain" [UniProtKB:P02489] synonym: "Heat shock protein beta-4" EXACT [UniProtKB:P02489] synonym: "HspB4" EXACT [UniProtKB:P02489] xref: EMBL:AAA52105.1 xref: EMBL:AAA52106.1 xref: EMBL:AAA97523.1 xref: EMBL:AAC50900.1 xref: EMBL:AAH69528.1 xref: EMBL:BAA95535.1 xref: EMBL:CAA32891.1 xref: UniProtKB:P02489 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017468 ! CRYAA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0064523 ! CRYAA_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0064524 ! CRYAA_HUMAN-Phosphothreonine13 relationship: transforms_into CCO:B0064525 ! CRYAA_HUMAN-Omega-N-methylated arginine21 relationship: transforms_into CCO:B0064526 ! CRYAA_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0064527 ! CRYAA_HUMAN-N6-acetyllysine70 relationship: transforms_into CCO:B0064528 ! CRYAA_HUMAN-N6-acetyllysine78 relationship: transforms_into CCO:B0064529 ! CRYAA_HUMAN-N6-acetyllysine88 relationship: transforms_into CCO:B0064530 ! CRYAA_HUMAN-lysine88 relationship: transforms_into CCO:B0064531 ! CRYAA_HUMAN-asparagine101 relationship: transforms_into CCO:B0064532 ! CRYAA_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0064533 ! CRYAA_HUMAN-Phosphothreonine140 relationship: transforms_into CCO:B0064534 ! CRYAA_HUMAN-N6-acetyllysine145 [Term] id: CCO:B0054861 name: CRYAB_HUMAN def: "Alpha-crystallin B chain" [UniProtKB:P02511] synonym: "Alpha(B)-crystallin" EXACT [UniProtKB:P02511] synonym: "Heat shock protein beta-5" EXACT [UniProtKB:P02511] synonym: "HspB5" EXACT [UniProtKB:P02511] synonym: "Renal carcinoma antigen NY-REN-27" EXACT [UniProtKB:P02511] synonym: "Rosenthal fiber component" EXACT [UniProtKB:P02511] xref: EMBL:AAA52104.1 xref: EMBL:AAA60267.1 xref: EMBL:AAB23453.1 xref: EMBL:AAC19161.1 xref: EMBL:AAH07008.1 xref: EMBL:AAP35416.1 xref: EMBL:ACA05949.1 xref: EMBL:BAG36739.1 xref: EMBL:EAW67162.1 xref: UniProtKB:B0YIX0 xref: UniProtKB:O43416 xref: UniProtKB:P02511 xref: UniProtKB:Q9UC37 xref: UniProtKB:Q9UC38 xref: UniProtKB:Q9UC39 xref: UniProtKB:Q9UC40 xref: UniProtKB:Q9UC41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017469 ! CRYAB_human relationship: has_function CCO:F0001488 ! structural constituent of eye lens relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007411 ! app-apbb1-6 physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0018622 ! app-nsf-3 physical interaction relationship: participates_in CCO:I0018847 ! hspb8-cryab-1 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0064535 ! CRYAB_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0064536 ! CRYAB_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0064537 ! CRYAB_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0064538 ! CRYAB_HUMAN-Omega-N-methylated arginine22 relationship: transforms_into CCO:B0064539 ! CRYAB_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0064540 ! CRYAB_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0064541 ! CRYAB_HUMAN-Omega-N-methylated arginine50 relationship: transforms_into CCO:B0064542 ! CRYAB_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0064543 ! CRYAB_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0064544 ! CRYAB_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0064545 ! CRYAB_HUMAN-N6-acetyllysine92 [Term] id: CCO:B0054862 name: APOE_HUMAN def: "Apolipoprotein E precursor" [UniProtKB:P02649] synonym: "Apo-E" EXACT [UniProtKB:P02649] xref: EMBL:AAB59397.1 xref: EMBL:AAB59518.1 xref: EMBL:AAB59546.1 xref: EMBL:AAD02505.1 xref: EMBL:AAG27089.1 xref: EMBL:AAH03557.1 xref: EMBL:BAA96080.1 xref: UniProtKB:P02649 xref: UniProtKB:Q9P2S4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016995 ! APOE_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0003584 ! cholesterol transporter activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006266 ! metal chelating activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007317 ! tau protein binding relationship: has_function CCO:F0008007 ! apolipoprotein E receptor binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001156 ! extrinsic to external side of plasma membrane relationship: located_in CCO:C0001672 ! chylomicron relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0002141 ! very-low-density lipoprotein particle relationship: located_in CCO:C0002142 ! low-density lipoprotein particle relationship: located_in CCO:C0002143 ! intermediate-density lipoprotein particle relationship: located_in CCO:C0002144 ! high-density lipoprotein particle relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: participates_in CCO:P0000975 ! negative regulation of platelet activation relationship: participates_in CCO:P0001150 ! cGMP-mediated signaling relationship: participates_in CCO:P0001276 ! regulation of axon extension relationship: participates_in CCO:P0001321 ! positive regulation of cGMP biosynthetic process relationship: participates_in CCO:P0001634 ! Cdc42 protein signal transduction relationship: participates_in CCO:P0002238 ! negative regulation of blood vessel endothelial cell migration relationship: participates_in CCO:P0002785 ! regulation of neuronal synaptic plasticity relationship: participates_in CCO:P0003013 ! positive regulation of membrane protein ectodomain proteolysis [Term] id: CCO:B0054863 name: APOA2_HUMAN def: "Apolipoprotein A-II precursor" [UniProtKB:P02652] synonym: "Apo-AII" EXACT [UniProtKB:P02652] synonym: "ApoA-II" EXACT [UniProtKB:P02652] xref: EMBL:AAA51701.1 xref: EMBL:AAH05282.1 xref: EMBL:AAM49807.1 xref: EMBL:AAP35432.1 xref: EMBL:CAA25467.1 xref: EMBL:CAA26474.1 xref: EMBL:CAA26665.1 xref: EMBL:CAA28583.1 xref: EMBL:CAH72151.1 xref: UniProtKB:P02652 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016992 ! APOA2_human relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005528 ! apolipoprotein receptor binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008232 ! lipase inhibitor activity relationship: has_function CCO:F0008244 ! phosphatidylcholine-sterol O-acyltransferase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0001672 ! chylomicron relationship: located_in CCO:C0002141 ! very-low-density lipoprotein particle relationship: located_in CCO:C0002142 ! low-density lipoprotein particle relationship: located_in CCO:C0002144 ! high-density lipoprotein particle relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:P0001482 ! regulation of protein stability relationship: participates_in CCO:P0002357 ! positive regulation of interleukin-8 biosynthetic process relationship: participates_in CCO:P0002938 ! negative regulation of lipoprotein metabolic process relationship: transforms_into CCO:B0065694 ! APOA2_HUMAN-Pyrrolidone carboxylic acid24 [Term] id: CCO:B0054864 name: APOC3_HUMAN def: "Apolipoprotein C-III precursor" [UniProtKB:P02656] synonym: "Apo-CIII" EXACT [UniProtKB:P02656] synonym: "ApoC-III" EXACT [UniProtKB:P02656] xref: EMBL:AAA51760.1 xref: EMBL:AAA51761.1 xref: EMBL:AAB59372.1 xref: EMBL:AAB59515.1 xref: EMBL:AAH27977.1 xref: EMBL:AAI21082.1 xref: EMBL:AAQ91810.1 xref: EMBL:AAS68230.1 xref: EMBL:CAA24757.1 xref: EMBL:CAA25233.1 xref: EMBL:CAA25644.1 xref: EMBL:CAA25648.1 xref: EMBL:CAA26895.1 xref: UniProtKB:P02656 xref: UniProtKB:Q08E83 xref: UniProtKB:Q6Q786 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016994 ! APOC3_human relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001672 ! chylomicron relationship: located_in CCO:C0002141 ! very-low-density lipoprotein particle relationship: located_in CCO:C0002143 ! intermediate-density lipoprotein particle relationship: located_in CCO:C0002146 ! spherical high-density lipoprotein particle relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001634 ! Cdc42 protein signal transduction relationship: participates_in CCO:P0002514 ! negative regulation of fatty acid biosynthetic process [Term] id: CCO:B0054865 name: FIBA_HUMAN def: "Fibrinogen alpha chain precursor" [UniProtKB:P02671] xref: EMBL:AAA17055.1 xref: EMBL:AAA17056.1 xref: EMBL:AAA52426.1 xref: EMBL:AAA52427.1 xref: EMBL:AAA52428.1 xref: EMBL:AAA52444.1 xref: EMBL:AAC97142.1 xref: EMBL:AAC97143.1 xref: EMBL:AAK31372.1 xref: EMBL:AAK31373.1 xref: UniProtKB:P02671 xref: UniProtKB:Q9BX62 xref: UniProtKB:Q9UCH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017805 ! FGA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017270 ! fga-fgb-2 physical interaction relationship: participates_in CCO:I0017794 ! fga-fgb-1 physical interaction relationship: participates_in CCO:I0018464 ! bat2-fga physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066187 ! FIBA_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0066188 ! FIBA_HUMAN-Phosphotyrosine277 relationship: transforms_into CCO:B0066189 ! FIBA_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0066190 ! FIBA_HUMAN-Phosphothreonine412 relationship: transforms_into CCO:B0066191 ! FIBA_HUMAN-Phosphoserine524 relationship: transforms_into CCO:B0066192 ! FIBA_HUMAN-Phosphoserine549 relationship: transforms_into CCO:B0066193 ! FIBA_HUMAN-Phosphoserine609 [Term] id: CCO:B0054866 name: FIBB_HUMAN def: "Fibrinogen beta chain precursor" [UniProtKB:P02675] xref: EMBL:AAA18024.2 xref: EMBL:AAA52429.1 xref: EMBL:AAA52445.1 xref: EMBL:AAA98115.1 xref: EMBL:AAA98116.1 xref: EMBL:AAI06761.1 xref: EMBL:AAK62470.1 xref: EMBL:CAA28674.1 xref: UniProtKB:P02675 xref: UniProtKB:Q3KPF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017806 ! FGB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:I0017270 ! fga-fgb-2 physical interaction relationship: participates_in CCO:I0017794 ! fga-fgb-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066194 ! FIBB_HUMAN-Pyrrolidone carboxylic acid31 [Term] id: CCO:B0054867 name: FIBG_HUMAN def: "Fibrinogen gamma chain precursor" [UniProtKB:P02679] xref: EMBL:AAA52430.1 xref: EMBL:AAA52431.1 xref: EMBL:AAB59530.1 xref: EMBL:AAB59531.1 xref: EMBL:AAF22036.1 xref: EMBL:AAH07044.1 xref: EMBL:AAH21674.1 xref: EMBL:AAK19751.2 xref: EMBL:AAK19752.2 xref: EMBL:CAA24944.1 xref: EMBL:CAA35837.1 xref: UniProtKB:P02679 xref: UniProtKB:P04469 xref: UniProtKB:P04470 xref: UniProtKB:Q96A14 xref: UniProtKB:Q96KJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017807 ! FGG_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:I0017270 ! fga-fgb-2 physical interaction relationship: participates_in CCO:I0017794 ! fga-fgb-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066195 ! FIBG_HUMAN-Sulfotyrosine444 relationship: transforms_into CCO:B0066196 ! FIBG_HUMAN-Sulfotyrosine448 [Term] id: CCO:B0054868 name: ACHA_HUMAN def: "Acetylcholine receptor subunit alpha precursor" [UniProtKB:P02708] xref: EMBL:AAD14247.1 xref: EMBL:CAA26344.1 xref: EMBL:CAA34960.1 xref: EMBL:CAA49705.1 xref: EMBL:CAA68731.1 xref: UniProtKB:P02708 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016893 ! CHRNA1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001300 ! neuromuscular junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054869 name: SAA_HUMAN def: "Serum amyloid A protein precursor" [UniProtKB:P02735] synonym: "SAA" EXACT [UniProtKB:P02735] xref: EMBL:AAA60297.1 xref: EMBL:AAA64799.1 xref: EMBL:AAA64800.1 xref: EMBL:AAA64801.1 xref: EMBL:AAA85338.1 xref: EMBL:AAB59539.1 xref: EMBL:AAH07022.1 xref: EMBL:AAH20795.1 xref: EMBL:AAI05797.1 xref: EMBL:CAA35804.1 xref: EMBL:CAA35805.1 xref: EMBL:CAA35806.1 xref: EMBL:CAA35807.1 xref: EMBL:CAA35809.1 xref: EMBL:CAA35810.1 xref: EMBL:CAA39974.1 xref: EMBL:CAA39975.1 xref: UniProtKB:P02735 xref: UniProtKB:P02736 xref: UniProtKB:P02737 xref: UniProtKB:Q16730 xref: UniProtKB:Q16834 xref: UniProtKB:Q16835 xref: UniProtKB:Q16879 xref: UniProtKB:Q3KRB3 xref: UniProtKB:Q96QN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019827 ! SAA1_human relationship: encoded_by CCO:G0019828 ! SAA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion relationship: transforms_into CCO:B0070288 ! SAA_HUMAN-N4,N4-dimethylasparagine101 [Term] id: CCO:B0054870 name: CO9_HUMAN def: "Complement component C9 precursor" [UniProtKB:P02748] xref: EMBL:AAA51889.1 xref: EMBL:AAA51890.1 xref: EMBL:AAH20721.1 xref: EMBL:CAA26117.1 xref: EMBL:CAA69849.1 xref: UniProtKB:P02748 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017426 ! C9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000204 ! membrane attack complex relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation [Term] id: CCO:B0054871 name: APOH_HUMAN def: "Beta-2-glycoprotein 1 precursor" [UniProtKB:P02749] synonym: "Activated protein C-binding protein" EXACT [UniProtKB:P02749] synonym: "Anticardiolipin cofactor" EXACT [UniProtKB:P02749] synonym: "APC inhibitor" EXACT [UniProtKB:P02749] synonym: "Apo-H" EXACT [UniProtKB:P02749] synonym: "Apolipoprotein H" EXACT [UniProtKB:P02749] synonym: "B2GPI" EXACT [UniProtKB:P02749] synonym: "Beta(2)GPI" EXACT [UniProtKB:P02749] synonym: "Beta-2-glycoprotein I" EXACT [UniProtKB:P02749] xref: EMBL:AAA51766.1 xref: EMBL:AAB21330.1 xref: EMBL:AAH20703.1 xref: EMBL:AAH26283.1 xref: EMBL:AAP72014.1 xref: EMBL:CAA37664.1 xref: EMBL:CAA40977.1 xref: EMBL:CAA41113.1 xref: EMBL:CAA72279.1 xref: EMBL:CAA76845.1 xref: UniProtKB:P02749 xref: UniProtKB:Q9UCN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016996 ! APOH_human relationship: has_function CCO:F0000251 ! glycoprotein binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005863 ! eukaryotic cell surface binding relationship: has_function CCO:F0008246 ! lipoprotein lipase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0001672 ! chylomicron relationship: participates_in CCO:P0001763 ! negative regulation of myeloid cell apoptosis relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0054872 name: AMBP_HUMAN def: "Protein AMBP precursor" [UniProtKB:P02760] xref: EMBL:AAA59196.1 xref: EMBL:AAH41593.1 xref: EMBL:AAT11154.1 xref: EMBL:BAF83526.1 xref: EMBL:CAA27803.1 xref: EMBL:CAA28182.1 xref: EMBL:CAA38585.1 xref: EMBL:CAA38586.1 xref: EMBL:CAA38587.1 xref: EMBL:CAI15899.1 xref: EMBL:EAW87404.1 xref: UniProtKB:P00977 xref: UniProtKB:P02759 xref: UniProtKB:P02760 xref: UniProtKB:P78491 xref: UniProtKB:Q2TU33 xref: UniProtKB:Q5TBD7 xref: UniProtKB:Q9UC58 xref: UniProtKB:Q9UDI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016957 ! AMBP_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0004194 ! calcium channel inhibitor activity relationship: has_function CCO:F0004195 ! IgA binding relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0004387 ! trypsin inhibitor activity relationship: has_function CCO:F0004480 ! plasmin inhibitor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006262 ! calcium oxalate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0002690 ! negative regulation of JNK cascade [Term] id: CCO:B0054873 name: FETUA_HUMAN def: "Alpha-2-HS-glycoprotein precursor" [UniProtKB:P02765] synonym: "Alpha-2-Z-globulin" EXACT [UniProtKB:P02765] synonym: "Ba-alpha-2-glycoprotein" EXACT [UniProtKB:P02765] synonym: "Fetuin-A" EXACT [UniProtKB:P02765] xref: EMBL:AAA51683.1 xref: EMBL:AAF69649.1 xref: EMBL:AAH48198.1 xref: EMBL:AAH52590.1 xref: EMBL:BAA22651.1 xref: EMBL:BAA22652.1 xref: EMBL:BAA92189.1 xref: UniProtKB:O14961 xref: UniProtKB:O14962 xref: UniProtKB:P02765 xref: UniProtKB:Q9P152 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017778 ! AHSG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002705 ! negative regulation of insulin receptor signaling pathway relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis relationship: transforms_into CCO:B0066169 ! FETUA_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0066170 ! FETUA_HUMAN-Phosphoserine325 relationship: transforms_into CCO:B0066171 ! FETUA_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0066172 ! FETUA_HUMAN-Phosphoserine330 [Term] id: CCO:B0054874 name: ALBU_HUMAN def: "Serum albumin precursor" [UniProtKB:P02768] xref: EMBL:AAA51688.1 xref: EMBL:AAA64922.1 xref: EMBL:AAA98797.1 xref: EMBL:AAA98798.1 xref: EMBL:AAF01333.1 xref: EMBL:AAF22034.1 xref: EMBL:AAF69594.1 xref: EMBL:AAF69644.1 xref: EMBL:AAF71067.1 xref: EMBL:AAG35503.1 xref: EMBL:AAH14308.1 xref: EMBL:AAH34023.1 xref: EMBL:AAH36003.1 xref: EMBL:AAH41789.1 xref: EMBL:AAN17825.1 xref: EMBL:AAQ89947.1 xref: EMBL:AAT11155.1 xref: EMBL:AAT52213.1 xref: EMBL:AAU21642.1 xref: EMBL:ABJ16448.1 xref: EMBL:ABS29264.1 xref: EMBL:CAA00606.1 xref: EMBL:CAA23753.1 xref: EMBL:CAA23754.1 xref: EMBL:CAH18185.1 xref: EMBL:EAX05676.1 xref: UniProtKB:O95574 xref: UniProtKB:P02768 xref: UniProtKB:P04277 xref: UniProtKB:Q13140 xref: UniProtKB:Q645G4 xref: UniProtKB:Q68DN5 xref: UniProtKB:Q6UXK4 xref: UniProtKB:Q86YG0 xref: UniProtKB:Q9P157 xref: UniProtKB:Q9P1I7 xref: UniProtKB:Q9UHS3 xref: UniProtKB:Q9UJZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016952 ! ALB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0002995 ! toxin binding relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0004183 ! oxygen binding relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0019891 ! alb-luc7l2 physical interaction relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002154 ! negative regulation of non-apoptotic programmed cell death relationship: transforms_into CCO:B0065588 ! ALBU_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0065589 ! ALBU_HUMAN-Phosphotyrosine108 relationship: transforms_into CCO:B0065590 ! ALBU_HUMAN-Phosphotyrosine164 [Term] id: CCO:B0054875 name: CXL10_HUMAN def: "C-X-C motif chemokine 10 precursor" [UniProtKB:P02778] synonym: "10 kDa interferon-gamma-induced protein" EXACT [UniProtKB:P02778] synonym: "Gamma-IP10" EXACT [UniProtKB:P02778] synonym: "IP-10" EXACT [UniProtKB:P02778] synonym: "Small-inducible cytokine B10" EXACT [UniProtKB:P02778] xref: EMBL:AAH10954.1 xref: EMBL:CAA26370.1 xref: UniProtKB:P02778 xref: UniProtKB:Q96QJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017504 ! CXCL10_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0054876 name: TRFE_HUMAN def: "Serotransferrin precursor" [UniProtKB:P02787] synonym: "Beta-1-metal-binding globulin" EXACT [UniProtKB:P02787] synonym: "Siderophilin" EXACT [UniProtKB:P02787] synonym: "Transferrin" EXACT [UniProtKB:P02787] xref: EMBL:AAA61140.1 xref: EMBL:AAA61141.1 xref: EMBL:AAA61142.1 xref: EMBL:AAA61143.2 xref: EMBL:AAA61145.1 xref: EMBL:AAA61147.1 xref: EMBL:AAA61148.1 xref: EMBL:AAA61233.1 xref: EMBL:AAB22049.1 xref: EMBL:AAB97880.1 xref: EMBL:AAC63506.1 xref: EMBL:AAF22007.1 xref: EMBL:AAH59367.1 xref: EMBL:AAK77664.1 xref: EMBL:AAP45055.1 xref: EMBL:CAA28265.1 xref: EMBL:CAB96907.1 xref: UniProtKB:O43890 xref: UniProtKB:P02787 xref: UniProtKB:Q9NQB8 xref: UniProtKB:Q9UHV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020350 ! TF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017410 ! tfrc-tf physical interaction relationship: participates_in CCO:I0019871 ! tubb4-tf physical interaction relationship: participates_in CCO:I0020663 ! sh3bp2-tf physical interaction relationship: participates_in CCO:P0001481 ! positive regulation of myelination relationship: transforms_into CCO:B0071536 ! TRFE_HUMAN-Omega-N-methylated arginine42 relationship: transforms_into CCO:B0071537 ! TRFE_HUMAN-Phosphotyrosine536 [Term] id: CCO:B0054877 name: MT2_HUMAN def: "Metallothionein-2" [UniProtKB:P02795] synonym: "Metallothionein-2A" EXACT [UniProtKB:P02795] synonym: "Metallothionein-II" EXACT [UniProtKB:P02795] synonym: "MT-2" EXACT [UniProtKB:P02795] synonym: "MT-II" EXACT [UniProtKB:P02795] xref: EMBL:AAA59583.1 xref: EMBL:AAA59584.1 xref: EMBL:AAB24908.1 xref: EMBL:AAH07034.1 xref: EMBL:AAH70289.1 xref: EMBL:AAP35979.1 xref: EMBL:ABC79300.1 xref: EMBL:CAA23841.1 xref: EMBL:CAA65915.1 xref: UniProtKB:P02795 xref: UniProtKB:Q14823 xref: UniProtKB:Q2HXR9 xref: UniProtKB:Q53XT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018668 ! MT2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015880 ! spink7-mt2a-1 direct interaction relationship: participates_in CCO:I0017806 ! mt2a-spink7 physical interaction relationship: participates_in CCO:I0017807 ! spink7-mt2a-2 physical interaction relationship: participates_in CCO:I0017826 ! mt2a-prkd1 physical interaction relationship: participates_in CCO:I0018248 ! mt2a-cxorf40a-2 physical interaction relationship: participates_in CCO:I0018564 ! cxorf40a-mt2a-1 physical interaction relationship: participates_in CCO:I0018724 ! spink7-mt2a physical interaction relationship: participates_in CCO:I0018727 ! mt2a-prkd1-1 physical interaction relationship: participates_in CCO:I0018758 ! prkd1-mt2a-2 physical interaction relationship: participates_in CCO:I0018759 ! mt2a-prkd1-2 colocalization relationship: participates_in CCO:I0019208 ! prkd1-mt2a physical interaction relationship: participates_in CCO:I0019209 ! prkd1-mt2a-1 physical interaction relationship: participates_in CCO:I0019210 ! mt2a-prkd1-3 colocalization relationship: participates_in CCO:I0019480 ! spink7-mt2a-3 colocalization relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: transforms_into CCO:B0068303 ! MT2_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0068304 ! MT2_HUMAN-N6-acetyllysine51 [Term] id: CCO:B0054878 name: OSTC_HUMAN def: "Osteocalcin precursor" [UniProtKB:P02818] synonym: "BGP" EXACT [UniProtKB:P02818] synonym: "Bone Gla protein" EXACT [UniProtKB:P02818] synonym: "Gamma-carboxyglutamic acid-containing protein" EXACT [UniProtKB:P02818] xref: EMBL:AAI13433.1 xref: EMBL:AAI13435.1 xref: EMBL:AAY16981.1 xref: EMBL:CAA27763.1 xref: EMBL:CAA35996.1 xref: EMBL:CAA37736.1 xref: EMBL:CAI15541.1 xref: EMBL:EAW52986.1 xref: UniProtKB:P02818 xref: UniProtKB:Q5TCK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019243 ! BGLAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002484 ! regulation of osteoclast differentiation relationship: transforms_into CCO:B0068998 ! OSTC_HUMAN-4-carboxyglutamate68 relationship: transforms_into CCO:B0068999 ! OSTC_HUMAN-4-carboxyglutamate72 relationship: transforms_into CCO:B0069000 ! OSTC_HUMAN-4-carboxyglutamate75 [Term] id: CCO:B0054879 name: OPSB_HUMAN def: "Blue-sensitive opsin" [UniProtKB:P03999] synonym: "Blue cone photoreceptor pigment" EXACT [UniProtKB:P03999] synonym: "BOP" EXACT [UniProtKB:P03999] xref: EMBL:AAA35608.1 xref: EMBL:AAB05207.1 xref: EMBL:AAC51334.1 xref: EMBL:AAL31362.1 xref: UniProtKB:P03999 xref: UniProtKB:Q13877 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019051 ! OPN1SW_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000185 ! photoreceptor outer segment relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054880 name: OPSR_HUMAN def: "Red-sensitive opsin" [UniProtKB:P04000] synonym: "Red cone photoreceptor pigment" EXACT [UniProtKB:P04000] xref: EMBL:AAB59524.1 xref: EMBL:CAA92342.1 xref: UniProtKB:P04000 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019055 ! OPN1LW_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054881 name: OPSG_HUMAN def: "Green-sensitive opsin" [UniProtKB:P04001] synonym: "Green cone photoreceptor pigment" EXACT [UniProtKB:P04001] xref: EMBL:AAB59503.1 xref: EMBL:AAB59525.1 xref: UniProtKB:P04001 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019053 ! OPN1MW_human relationship: encoded_by CCO:G0019054 ! OPN1MW2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054882 name: TDT_HUMAN def: "DNA nucleotidylexotransferase" [UniProtKB:P04053] synonym: "EC 2.7.7.31" EXACT [UniProtKB:P04053] synonym: "Terminal addition enzyme" EXACT [UniProtKB:P04053] synonym: "Terminal deoxynucleotidyltransferase" EXACT [UniProtKB:P04053] synonym: "Terminal transferase" EXACT [UniProtKB:P04053] xref: EMBL:AAA36726.1 xref: EMBL:AAA53100.1 xref: EMBL:AAA61136.1 xref: EMBL:AAA61137.1 xref: EMBL:AAH12920.1 xref: EMBL:BAB72001.1 xref: UniProtKB:P04053 xref: UniProtKB:Q96E50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020222 ! DNTT_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000416 ! DNA nucleotidylexotransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0054883 name: PA21B_HUMAN def: "Phospholipase A2 precursor" [UniProtKB:P04054] synonym: "EC 3.1.1.4" EXACT [UniProtKB:P04054] synonym: "Group IB phospholipase A2" EXACT [UniProtKB:P04054] synonym: "Phosphatidylcholine 2-acylhydrolase" EXACT [UniProtKB:P04054] xref: EMBL:AAA36450.1 xref: EMBL:AAA60107.1 xref: EMBL:AAB95635.1 xref: EMBL:AAI06726.1 xref: EMBL:AAI06727.1 xref: EMBL:AAR05441.1 xref: EMBL:BAG34772.1 xref: EMBL:EAW98184.1 xref: UniProtKB:B2R4H5 xref: UniProtKB:P04054 xref: UniProtKB:Q3KPI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019282 ! PLA2G1B_human relationship: has_function CCO:F0001002 ! phospholipase A2 activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004941 ! bile acid binding relationship: has_function CCO:F0005862 ! cell surface binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006802 ! calcium-dependent phospholipase A2 activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0054884 name: PROC_HUMAN def: "Vitamin K-dependent protein C precursor" [UniProtKB:P04070] synonym: "Anticoagulant protein C" EXACT [UniProtKB:P04070] synonym: "Autoprothrombin IIA" EXACT [UniProtKB:P04070] synonym: "Blood coagulation factor XIV" EXACT [UniProtKB:P04070] synonym: "EC 3.4.21.69" EXACT [UniProtKB:P04070] xref: EMBL:AAA60164.1 xref: EMBL:AAA60165.1 xref: EMBL:AAA60166.1 xref: EMBL:AAB26335.1 xref: EMBL:AAH34377.1 xref: EMBL:AAK56377.1 xref: EMBL:CAA26528.1 xref: UniProtKB:P04070 xref: UniProtKB:Q15189 xref: UniProtKB:Q15190 xref: UniProtKB:Q16001 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019514 ! PROC_human relationship: has_function CCO:F0000333 ! protein C (activated) activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0069527 ! PROC_HUMAN-4-carboxyglutamate48 relationship: transforms_into CCO:B0069528 ! PROC_HUMAN-4-carboxyglutamate49 relationship: transforms_into CCO:B0069529 ! PROC_HUMAN-4-carboxyglutamate56 relationship: transforms_into CCO:B0069530 ! PROC_HUMAN-4-carboxyglutamate58 relationship: transforms_into CCO:B0069531 ! PROC_HUMAN-4-carboxyglutamate61 relationship: transforms_into CCO:B0069532 ! PROC_HUMAN-4-carboxyglutamate62 relationship: transforms_into CCO:B0069533 ! PROC_HUMAN-4-carboxyglutamate67 relationship: transforms_into CCO:B0069534 ! PROC_HUMAN-4-carboxyglutamate68 relationship: transforms_into CCO:B0069535 ! PROC_HUMAN-4-carboxyglutamate71 relationship: transforms_into CCO:B0069536 ! PROC_HUMAN-3-hydroxyaspartate113 [Term] id: CCO:B0054885 name: CSF2_HUMAN def: "Granulocyte-macrophage colony-stimulating factor precursor" [UniProtKB:P04141] synonym: "Colony-stimulating factor" EXACT [UniProtKB:P04141] synonym: "CSF" EXACT [UniProtKB:P04141] synonym: "GM-CSF" EXACT [UniProtKB:P04141] synonym: "Molgramostin" EXACT [UniProtKB:P04141] synonym: "Sargramostim" EXACT [UniProtKB:P04141] xref: EMBL:AAA52121.1 xref: EMBL:AAA52122.1 xref: EMBL:AAA52578.1 xref: EMBL:AAA98768.1 xref: EMBL:AAC08707.1 xref: EMBL:AAI08725.1 xref: EMBL:AAI14000.1 xref: EMBL:AAK51563.1 xref: EMBL:AAM44054.1 xref: EMBL:CAA26822.1 xref: UniProtKB:P04141 xref: UniProtKB:Q2VPI8 xref: UniProtKB:Q8NFI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017474 ! CSF2_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001431 ! granulocyte macrophage colony-stimulating factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002088 ! positive regulation of tyrosine phosphorylation of Stat5 protein relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression [Term] id: CCO:B0054886 name: GCR_HUMAN def: "Glucocorticoid receptor" [UniProtKB:P04150] synonym: "GR" EXACT [UniProtKB:P04150] synonym: "Nuclear receptor subfamily 3 group C member 1" EXACT [UniProtKB:P04150] xref: EMBL:AAA16603.1 xref: EMBL:AAA53151.1 xref: EMBL:AAA88049.1 xref: EMBL:AAB20466.1 xref: EMBL:AAB64353.1 xref: EMBL:AAB64354.1 xref: EMBL:AAC34207.1 xref: EMBL:AAH15610.1 xref: EMBL:AAQ97180.1 xref: EMBL:BAD97314.1 xref: EMBL:CAA26976.1 xref: EMBL:CAA27054.1 xref: EMBL:CAE45716.1 xref: UniProtKB:P04150 xref: UniProtKB:P04151 xref: UniProtKB:Q53EP5 xref: UniProtKB:Q6N0A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017897 ! NR3C1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016249 ! nr3c1-smarca4-1 physical interaction relationship: participates_in CCO:I0016250 ! nr3c1-smarca4-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066428 ! GCR_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0066429 ! GCR_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0066430 ! GCR_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0066431 ! GCR_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0066432 ! GCR_HUMAN-Phosphoserine226 [Term] id: CCO:B0054887 name: MYCN_HUMAN def: "N-myc proto-oncogene protein" [UniProtKB:P04198] xref: EMBL:AAA36370.1 xref: EMBL:AAA36371.1 xref: EMBL:AAA59885.1 xref: EMBL:AAH02712.1 xref: EMBL:CAA27037.1 xref: EMBL:CAA27038.1 xref: EMBL:CAA68678.1 xref: UniProtKB:P04198 xref: UniProtKB:Q6LDT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018693 ! MYCN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017389 ! mycn-max-1 physical interaction relationship: participates_in CCO:I0017390 ! mycn-nmi-1 physical interaction relationship: participates_in CCO:I0017398 ! mycn-nmi-6 physical interaction relationship: participates_in CCO:I0019512 ! mycn-max-2 physical interaction relationship: participates_in CCO:I0019513 ! mycn-nmi-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068363 ! MYCN_HUMAN-Phosphothreonine58 relationship: transforms_into CCO:B0068364 ! MYCN_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0068365 ! MYCN_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0068366 ! MYCN_HUMAN-Phosphoserine263 [Term] id: CCO:B0054888 name: MAS_HUMAN def: "MAS proto-oncogene" [UniProtKB:P04201] xref: EMBL:AAA36199.1 xref: EMBL:AAH69142.1 xref: EMBL:AAH69581.1 xref: EMBL:AAI10455.1 xref: EMBL:CAB72444.1 xref: EMBL:CAG47057.1 xref: UniProtKB:P04201 xref: UniProtKB:Q2TBC9 xref: UniProtKB:Q6FG47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018573 ! MAS1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054889 name: THY1_HUMAN def: "Thy-1 membrane glycoprotein precursor" [UniProtKB:P04216] synonym: "CD90 antigen" EXACT [UniProtKB:P04216] synonym: "CDw90" EXACT [UniProtKB:P04216] synonym: "Thy-1 antigen" EXACT [UniProtKB:P04216] xref: EMBL:AAA61180.1 xref: EMBL:AAB26353.2 xref: EMBL:AAG13904.1 xref: EMBL:AAH65559.1 xref: EMBL:CAB82306.1 xref: UniProtKB:P04216 xref: UniProtKB:Q16008 xref: UniProtKB:Q9NSP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020256 ! THY1_human relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005537 ! GPI anchor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0002949 ! negative regulation of axonogenesis relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002978 ! negative regulation of T cell receptor signaling pathway relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation relationship: participates_in CCO:P0003076 ! positive regulation of release of sequestered calcium ion into cytosol relationship: transforms_into CCO:B0071387 ! THY1_HUMAN-Pyrrolidone carboxylic acid20 [Term] id: CCO:B0054890 name: CD3D_HUMAN def: "T-cell surface glycoprotein CD3 delta chain precursor" [UniProtKB:P04234] synonym: "CD3d antigen" EXACT [UniProtKB:P04234] synonym: "T-cell receptor T3 delta chain" EXACT [UniProtKB:P04234] xref: EMBL:AAA51792.1 xref: EMBL:AAH39035.1 xref: EMBL:AAH70321.1 xref: EMBL:CAA25683.1 xref: EMBL:CAA27573.1 xref: UniProtKB:P04234 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017299 ! CD3D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0064153 ! CD3D_HUMAN-Phosphotyrosine149 relationship: transforms_into CCO:B0064154 ! CD3D_HUMAN-Phosphotyrosine160 [Term] id: CCO:B0054891 name: WNT1_HUMAN def: "Proto-oncogene protein Wnt-1 precursor" [UniProtKB:P04628] xref: EMBL:AAH74798.1 xref: EMBL:AAH74799.1 xref: EMBL:CAA26874.1 xref: UniProtKB:P04628 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020484 ! WNT1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0054892 name: NTRK1_HUMAN def: "High affinity nerve growth factor receptor precursor" [UniProtKB:P04629] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P04629] synonym: "Neurotrophic tyrosine kinase receptor type 1" EXACT [UniProtKB:P04629] synonym: "p140-TrkA" EXACT [UniProtKB:P04629] synonym: "Trk-A" EXACT [UniProtKB:P04629] synonym: "TRK1-transforming tyrosine kinase protein" EXACT [UniProtKB:P04629] xref: EMBL:AAA36770.1 xref: EMBL:AAH62580.1 xref: EMBL:AAP88292.1 xref: EMBL:BAA34355.1 xref: EMBL:CAA27243.1 xref: EMBL:CAA29888.1 xref: EMBL:CAA44719.1 xref: EMBL:CAA59936.1 xref: EMBL:CAH70010.1 xref: UniProtKB:P04629 xref: UniProtKB:P08119 xref: UniProtKB:Q15655 xref: UniProtKB:Q15656 xref: UniProtKB:Q5D056 xref: UniProtKB:Q5VZS2 xref: UniProtKB:Q7Z5C3 xref: UniProtKB:Q9UIU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018885 ! NTRK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018114 ! ngfb-ntrk1-1 direct interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0068877 ! NTRK1_HUMAN-Phosphotyrosine496 relationship: transforms_into CCO:B0068878 ! NTRK1_HUMAN-Phosphotyrosine676 relationship: transforms_into CCO:B0068879 ! NTRK1_HUMAN-Phosphotyrosine680 relationship: transforms_into CCO:B0068880 ! NTRK1_HUMAN-Phosphotyrosine681 relationship: transforms_into CCO:B0068881 ! NTRK1_HUMAN-Phosphotyrosine791 [Term] id: CCO:B0054893 name: TYSY_HUMAN def: "Thymidylate synthase" [UniProtKB:P04818] synonym: "EC 2.1.1.45" EXACT [UniProtKB:P04818] synonym: "TS" EXACT [UniProtKB:P04818] synonym: "TSase" EXACT [UniProtKB:P04818] xref: EMBL:AAH02567.1 xref: EMBL:AAH13919.1 xref: EMBL:AAH83512.1 xref: EMBL:BAA00404.1 xref: EMBL:BAA00472.1 xref: EMBL:BAB93473.1 xref: EMBL:CAA26178.1 xref: UniProtKB:P04818 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020397 ! TYMS_human relationship: has_function CCO:F0001157 ! thymidylate synthase activity relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0054894 name: IL4_HUMAN def: "Interleukin-4 precursor" [UniProtKB:P05112] synonym: "B-cell stimulatory factor 1" EXACT [UniProtKB:P05112] synonym: "Binetrakin" EXACT [UniProtKB:P05112] synonym: "BSF-1" EXACT [UniProtKB:P05112] synonym: "IL-4" EXACT [UniProtKB:P05112] synonym: "Lymphocyte stimulatory factor 1" EXACT [UniProtKB:P05112] synonym: "Pitrakinra" EXACT [UniProtKB:P05112] xref: EMBL:AAA59149.1 xref: EMBL:AAA59150.1 xref: EMBL:AAH67514.1 xref: EMBL:AAH70123.1 xref: EMBL:AAK71324.1 xref: EMBL:CAA29925.1 xref: EMBL:CAA57444.1 xref: UniProtKB:P05112 xref: UniProtKB:Q14630 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018265 ! IL4_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001438 ! interleukin-4 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0017788 ! il4-il4r-1 direct interaction relationship: participates_in CCO:I0017844 ! il2rg-il4r-1 physical interaction relationship: participates_in CCO:I0017845 ! il4r-il4-1 physical interaction relationship: participates_in CCO:I0017846 ! il4r-il4-2 physical interaction relationship: participates_in CCO:I0017980 ! il4r-il4-3 physical interaction relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002284 ! regulation of isotype switching relationship: participates_in CCO:P0002485 ! negative regulation of osteoclast differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002806 ! positive regulation of isotype switching to IgE isotypes relationship: participates_in CCO:P0002815 ! positive regulation of isotype switching to IgG isotypes [Term] id: CCO:B0054895 name: IL5_HUMAN def: "Interleukin-5 precursor" [UniProtKB:P05113] synonym: "B-cell differentiation factor I" EXACT [UniProtKB:P05113] synonym: "Eosinophil differentiation factor" EXACT [UniProtKB:P05113] synonym: "IL-5" EXACT [UniProtKB:P05113] synonym: "T-cell replacing factor" EXACT [UniProtKB:P05113] synonym: "TRF" EXACT [UniProtKB:P05113] xref: EMBL:AAA74469.1 xref: EMBL:AAA98620.1 xref: EMBL:AAH66282.1 xref: EMBL:AAK19759.1 xref: EMBL:CAA28390.1 xref: EMBL:CAA31210.1 xref: EMBL:CAA31211.1 xref: UniProtKB:P05113 xref: UniProtKB:Q13840 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018267 ! IL5_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001439 ! interleukin-5 receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0054896 name: PAI2_HUMAN def: "Plasminogen activator inhibitor 2 precursor" [UniProtKB:P05120] synonym: "Monocyte Arg-serpin" EXACT [UniProtKB:P05120] synonym: "PAI-2" EXACT [UniProtKB:P05120] synonym: "Placental plasminogen activator inhibitor" EXACT [UniProtKB:P05120] synonym: "Urokinase inhibitor" EXACT [UniProtKB:P05120] xref: EMBL:AAA36413.1 xref: EMBL:AAA36797.1 xref: EMBL:AAA60004.1 xref: EMBL:AAA60006.1 xref: EMBL:AAA60348.1 xref: EMBL:AAH12609.1 xref: EMBL:CAA68666.1 xref: UniProtKB:P05120 xref: UniProtKB:Q96E96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019291 ! SERPINB2_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001793 ! plasminogen activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054897 name: PERM_HUMAN def: "Myeloperoxidase precursor" [UniProtKB:P05164] synonym: "EC 1.11.1.7" EXACT [UniProtKB:P05164] synonym: "MPO" EXACT [UniProtKB:P05164] xref: EMBL:AAA59863.1 xref: EMBL:AAA59864.1 xref: EMBL:AAA59865.1 xref: EMBL:AAA59896.1 xref: EMBL:AAA60346.1 xref: EMBL:AAB25582.1 xref: EMBL:AAY68218.1 xref: EMBL:BAA03362.1 xref: EMBL:CAA28565.1 xref: EMBL:CAA33438.1 xref: UniProtKB:P05164 xref: UniProtKB:Q14862 xref: UniProtKB:Q4PJH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019369 ! MPO_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0069234 ! PERM_HUMAN-Cysteine sulfenic acid (-SOH)316 [Term] id: CCO:B0054898 name: HMGN2_HUMAN def: "Non-histone chromosomal protein HMG-17" [UniProtKB:P05204] synonym: "High-mobility group nucleosome-binding domain-containing protein 2" EXACT [UniProtKB:P05204] xref: EMBL:AAA52678.1 xref: EMBL:AAH00378.1 xref: EMBL:AAH03050.1 xref: EMBL:AAH14644.2 xref: EMBL:AAH32140.2 xref: EMBL:AAH70297.1 xref: EMBL:AAH71707.1 xref: EMBL:AAH72010.1 xref: EMBL:AAH72011.1 xref: EMBL:AAH75837.1 xref: EMBL:AAH81567.1 xref: EMBL:AAI10391.1 xref: EMBL:CAA31898.1 xref: EMBL:CAG46919.1 xref: EMBL:CAI21489.1 xref: UniProtKB:P05204 xref: UniProtKB:Q0VGD5 xref: UniProtKB:Q6FGI5 xref: UniProtKB:Q96C64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018143 ! HMGN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066832 ! HMGN2_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0066833 ! HMGN2_HUMAN-Phosphoserine29 [Term] id: CCO:B0054899 name: IL6_HUMAN def: "Interleukin-6 precursor" [UniProtKB:P05231] synonym: "B-cell stimulatory factor 2" EXACT [UniProtKB:P05231] synonym: "BSF-2" EXACT [UniProtKB:P05231] synonym: "CDF" EXACT [UniProtKB:P05231] synonym: "CTL differentiation factor" EXACT [UniProtKB:P05231] synonym: "Hybridoma growth factor" EXACT [UniProtKB:P05231] synonym: "IL-6" EXACT [UniProtKB:P05231] synonym: "Interferon beta-2" EXACT [UniProtKB:P05231] xref: EMBL:AAA52728.1 xref: EMBL:AAA52729.1 xref: EMBL:AAA59154.1 xref: EMBL:AAC41704.1 xref: EMBL:AAD13886.1 xref: EMBL:AAH15511.1 xref: EMBL:AAK48987.1 xref: EMBL:CAA27990.1 xref: EMBL:CAA27991.1 xref: EMBL:CAA28026.1 xref: EMBL:CAA28268.1 xref: EMBL:CAA68278.1 xref: UniProtKB:P05231 xref: UniProtKB:Q9UCU2 xref: UniProtKB:Q9UCU3 xref: UniProtKB:Q9UCU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018269 ! IL6_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001440 ! interleukin-6 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0018118 ! il6-il6r-1 physical interaction relationship: participates_in CCO:I0020344 ! il6-sh3gl2 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001795 ! positive regulation of peptidyl-serine phosphorylation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002271 ! negative regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002444 ! positive regulation of T-helper 2 cell differentiation relationship: participates_in CCO:P0002524 ! positive regulation of translation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002748 ! negative regulation of hormone secretion relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0054900 name: REG1A_HUMAN def: "Lithostathine-1-alpha precursor" [UniProtKB:P05451] synonym: "ICRF" EXACT [UniProtKB:P05451] synonym: "Islet cells regeneration factor" EXACT [UniProtKB:P05451] synonym: "Islet of Langerhans regenerating protein" EXACT [UniProtKB:P05451] synonym: "Pancreatic stone protein" EXACT [UniProtKB:P05451] synonym: "Pancreatic thread protein" EXACT [UniProtKB:P05451] synonym: "PSP" EXACT [UniProtKB:P05451] synonym: "PTP" EXACT [UniProtKB:P05451] synonym: "REG" EXACT [UniProtKB:P05451] synonym: "Regenerating protein I alpha" EXACT [UniProtKB:P05451] xref: EMBL:AAA36558.1 xref: EMBL:AAA36559.1 xref: EMBL:AAA60545.1 xref: EMBL:AAA60546.1 xref: EMBL:AAD51330.1 xref: EMBL:AAH05350.1 xref: UniProtKB:P05451 xref: UniProtKB:P11379 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019663 ! REG1A_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0069854 ! REG1A_HUMAN-Pyrrolidone carboxylic acid23 [Term] id: CCO:B0054901 name: CD5_HUMAN def: "T-cell surface glycoprotein CD5 precursor" [UniProtKB:P06127] synonym: "CD5 antigen" EXACT [UniProtKB:P06127] synonym: "Lymphocyte antigen T1/Leu-1" EXACT [UniProtKB:P06127] xref: EMBL:AAH27901.1 xref: EMBL:CAA27979.1 xref: EMBL:CAA61584.2 xref: UniProtKB:P06127 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017305 ! CD5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017842 ! cd5-cd72-1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0001401 ! T cell costimulation relationship: transforms_into CCO:B0064170 ! CD5_HUMAN-Phosphoserine439 relationship: transforms_into CCO:B0064171 ! CD5_HUMAN-Phosphotyrosine453 relationship: transforms_into CCO:B0064172 ! CD5_HUMAN-Phosphoserine460 [Term] id: CCO:B0054902 name: AGAL_HUMAN def: "Alpha-galactosidase A precursor" [UniProtKB:P06280] synonym: "Agalsidase" EXACT [UniProtKB:P06280] synonym: "Alpha-D-galactosidase A" EXACT [UniProtKB:P06280] synonym: "Alpha-D-galactoside galactohydrolase" EXACT [UniProtKB:P06280] synonym: "EC 3.2.1.22" EXACT [UniProtKB:P06280] synonym: "Melibiase" EXACT [UniProtKB:P06280] xref: EMBL:AAA51676.1 xref: EMBL:AAA52514.1 xref: EMBL:AAA52559.1 xref: EMBL:AAB64203.1 xref: EMBL:AAH02689.1 xref: EMBL:CAA29232.1 xref: EMBL:CAA32617.1 xref: EMBL:CAB55878.1 xref: UniProtKB:P06280 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016929 ! GLA_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds relationship: has_function CCO:F0000942 ! alpha-galactosidase activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005808 ! cation binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0002262 ! negative regulation of nitric oxide biosynthetic process [Term] id: CCO:B0054903 name: CCKN_HUMAN def: "Cholecystokinin precursor" [UniProtKB:P06307] synonym: "CCK" EXACT [UniProtKB:P06307] xref: EMBL:AAA53094.1 xref: EMBL:AAH08283.1 xref: EMBL:AAP35637.1 xref: EMBL:AAR89908.1 xref: UniProtKB:P06307 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017259 ! CCK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064111 ! CCKN_HUMAN-Sulfotyrosine97 relationship: transforms_into CCO:B0064112 ! CCKN_HUMAN-Phenylalanine amide103 relationship: transforms_into CCO:B0064113 ! CCKN_HUMAN-Sulfotyrosine111 relationship: transforms_into CCO:B0064114 ! CCKN_HUMAN-Sulfotyrosine113 [Term] id: CCO:B0054904 name: PRGR_HUMAN def: "Progesterone receptor" [UniProtKB:P06401] synonym: "Nuclear receptor subfamily 3 group C member 3" EXACT [UniProtKB:P06401] synonym: "PR" EXACT [UniProtKB:P06401] xref: EMBL:AAA60081.1 xref: EMBL:AAD01587.1 xref: EMBL:AAS00096.1 xref: EMBL:CAA36018.1 xref: UniProtKB:P06401 xref: UniProtKB:Q9UPF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019509 ! PGR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017650 ! hrmt1l1-pgr-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069500 ! PRGR_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0069501 ! PRGR_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0069502 ! PRGR_HUMAN-Phosphothreonine41 relationship: transforms_into CCO:B0069503 ! PRGR_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0069504 ! PRGR_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0069505 ! PRGR_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0069506 ! PRGR_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0069507 ! PRGR_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0069508 ! PRGR_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0069509 ! PRGR_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0069510 ! PRGR_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0069511 ! PRGR_HUMAN-Phosphothreonine430 relationship: transforms_into CCO:B0069512 ! PRGR_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0069513 ! PRGR_HUMAN-Phosphoserine554 relationship: transforms_into CCO:B0069514 ! PRGR_HUMAN-Phosphoserine676 relationship: transforms_into CCO:B0069515 ! PRGR_HUMAN-Phosphoserine793 [Term] id: CCO:B0054905 name: DPOLB_HUMAN def: "DNA polymerase beta" [UniProtKB:P06746] synonym: "EC 2.7.7.7" EXACT [UniProtKB:P06746] synonym: "EC 4.2.99.-" EXACT [UniProtKB:P06746] xref: EMBL:AAA60133.1 xref: EMBL:AAA60134.1 xref: EMBL:AAB59441.1 xref: EMBL:AAB60688.1 xref: EMBL:AAI00289.1 xref: EMBL:AAI06910.1 xref: EMBL:AAL91594.1 xref: EMBL:BAA06099.1 xref: EMBL:CAG38741.1 xref: EMBL:CAG46601.1 xref: UniProtKB:P06746 xref: UniProtKB:Q3KP48 xref: UniProtKB:Q6FI34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017608 ! POLB_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000436 ! spindle microtubule relationship: participates_in CCO:I0019787 ! polb-myst2 physical interaction relationship: participates_in CCO:I0020117 ! polb-tle1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0054906 name: CRF_HUMAN def: "Corticoliberin precursor" [UniProtKB:P06850] synonym: "Corticotropin-releasing factor" EXACT [UniProtKB:P06850] synonym: "Corticotropin-releasing hormone" EXACT [UniProtKB:P06850] synonym: "CRF" EXACT [UniProtKB:P06850] xref: EMBL:AAH02599.1 xref: EMBL:AAH11031.1 xref: EMBL:AAP36121.1 xref: EMBL:CAA23834.1 xref: UniProtKB:P06850 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017456 ! CRH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064466 ! CRF_HUMAN-Isoleucine amide194 [Term] id: CCO:B0054907 name: CALCA_HUMAN def: "Calcitonin gene-related peptide 1 precursor" [UniProtKB:P06881] synonym: "Alpha-type CGRP" EXACT [UniProtKB:P06881] synonym: "Calcitonin gene-related peptide I" EXACT [UniProtKB:P06881] synonym: "CGRP-I" EXACT [UniProtKB:P06881] xref: EMBL:AAA51912.1 xref: EMBL:AAA51914.1 xref: EMBL:AAA52011.1 xref: EMBL:AAA52012.1 xref: EMBL:CAA26190.1 xref: EMBL:CAA34070.1 xref: UniProtKB:P06881 xref: UniProtKB:Q93048 xref: UniProtKB:Q9UCP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017215 ! CALCA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000503 ! endothelial cell proliferation relationship: participates_in CCO:P0002465 ! positive regulation of macrophage differentiation relationship: participates_in CCO:P0002485 ! negative regulation of osteoclast differentiation relationship: participates_in CCO:P0003100 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: transforms_into CCO:B0064054 ! CALCA_HUMAN-Phenylalanine amide119 [Term] id: CCO:B0054908 name: GDN_HUMAN def: "Glia-derived nexin precursor" [UniProtKB:P07093] synonym: "GDN" EXACT [UniProtKB:P07093] synonym: "PN-1" EXACT [UniProtKB:P07093] synonym: "Protease inhibitor 7" EXACT [UniProtKB:P07093] synonym: "Protease nexin I" EXACT [UniProtKB:P07093] xref: EMBL:AAA35883.1 xref: EMBL:AAH15663.1 xref: UniProtKB:P07093 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017913 ! SERPINE2_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001246 ! regulation of proteolysis relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0054909 name: NFM_HUMAN def: "Neurofilament medium polypeptide" [UniProtKB:P07197] synonym: "160 kDa neurofilament protein" EXACT [UniProtKB:P07197] synonym: "Neurofilament 3" EXACT [UniProtKB:P07197] synonym: "Neurofilament triplet M protein" EXACT [UniProtKB:P07197] synonym: "NF-M" EXACT [UniProtKB:P07197] xref: EMBL:CAA68276.1 xref: UniProtKB:P07197 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018780 ! NEFM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017442 ! tnik-nef3 physical interaction relationship: participates_in CCO:P0001388 ! regulation of axon diameter relationship: transforms_into CCO:B0068671 ! NFM_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0068672 ! NFM_HUMAN-Phosphotyrosine320 relationship: transforms_into CCO:B0068673 ! NFM_HUMAN-Phosphoserine511 relationship: transforms_into CCO:B0068674 ! NFM_HUMAN-Phosphoserine545 relationship: transforms_into CCO:B0068675 ! NFM_HUMAN-Phosphoserine553 relationship: transforms_into CCO:B0068676 ! NFM_HUMAN-Phosphoserine559 relationship: transforms_into CCO:B0068677 ! NFM_HUMAN-Phosphoserine615 relationship: transforms_into CCO:B0068678 ! NFM_HUMAN-Phosphoserine620 relationship: transforms_into CCO:B0068679 ! NFM_HUMAN-Phosphoserine628 relationship: transforms_into CCO:B0068680 ! NFM_HUMAN-Phosphoserine633 relationship: transforms_into CCO:B0068681 ! NFM_HUMAN-Phosphoserine654 relationship: transforms_into CCO:B0068682 ! NFM_HUMAN-Phosphoserine659 relationship: transforms_into CCO:B0068683 ! NFM_HUMAN-Phosphoserine667 relationship: transforms_into CCO:B0068684 ! NFM_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0068685 ! NFM_HUMAN-Phosphoserine680 relationship: transforms_into CCO:B0068686 ! NFM_HUMAN-Phosphoserine685 relationship: transforms_into CCO:B0068687 ! NFM_HUMAN-Phosphoserine736 relationship: transforms_into CCO:B0068688 ! NFM_HUMAN-Phosphoserine783 relationship: transforms_into CCO:B0068689 ! NFM_HUMAN-Phosphoserine788 relationship: transforms_into CCO:B0068690 ! NFM_HUMAN-Phosphoserine837 [Term] id: CCO:B0054910 name: GPX1_HUMAN def: "Glutathione peroxidase 1" [UniProtKB:P07203] synonym: "Cellular glutathione peroxidase" EXACT [UniProtKB:P07203] synonym: "EC 1.11.1.9" EXACT [UniProtKB:P07203] synonym: "GPx-1" EXACT [UniProtKB:P07203] synonym: "GSHPx-1" EXACT [UniProtKB:P07203] xref: EMBL:AAA67540.2 xref: EMBL:AAA75389.2 xref: EMBL:AAH00742.3 xref: EMBL:AAP80181.1 xref: EMBL:CAA31992.1 xref: EMBL:CAA31993.1 xref: EMBL:CAA68491.1 xref: EMBL:CAB37833.1 xref: UniProtKB:P07203 xref: UniProtKB:Q7Z5H1 xref: UniProtKB:Q9BW12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018047 ! GPX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000838 ! induction of apoptosis by oxidative stress relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis relationship: participates_in CCO:P0001834 ! regulation of mammary gland epithelial cell proliferation relationship: participates_in CCO:P0002023 ! regulation of gene expression, epigenetic relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: transforms_into CCO:B0066575 ! GPX1_HUMAN-N6-acetyllysine146 [Term] id: CCO:B0054911 name: FES_HUMAN def: "Proto-oncogene tyrosine-protein kinase Fes/Fps" [UniProtKB:P07332] synonym: "C-Fes" EXACT [UniProtKB:P07332] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P07332] xref: EMBL:AAH35357.1 xref: EMBL:CAA29619.1 xref: EMBL:CAA36438.1 xref: UniProtKB:P07332 xref: UniProtKB:Q6GTU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017777 ! FES_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0066168 ! FES_HUMAN-Phosphotyrosine713 [Term] id: CCO:B0054912 name: CSF1R_HUMAN def: "Macrophage colony-stimulating factor 1 receptor precursor" [UniProtKB:P07333] synonym: "c-fms" EXACT [UniProtKB:P07333] synonym: "CD115 antigen" EXACT [UniProtKB:P07333] synonym: "CSF-1-R" EXACT [UniProtKB:P07333] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P07333] synonym: "Fms proto-oncogene" EXACT [UniProtKB:P07333] xref: EMBL:AAA35834.1 xref: EMBL:AAA35848.1 xref: EMBL:AAA35849.1 xref: EMBL:AAA58421.1 xref: EMBL:AAB51235.1 xref: EMBL:AAB51696.1 xref: EMBL:CAA27300.1 xref: UniProtKB:P07333 xref: UniProtKB:Q6LDW5 xref: UniProtKB:Q6LDY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017473 ! CSF1R_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0064550 ! CSF1R_HUMAN-Phosphoserine555 relationship: transforms_into CCO:B0064551 ! CSF1R_HUMAN-Phosphotyrosine556 relationship: transforms_into CCO:B0064552 ! CSF1R_HUMAN-Phosphothreonine562 relationship: transforms_into CCO:B0064553 ! CSF1R_HUMAN-Phosphothreonine567 relationship: transforms_into CCO:B0064554 ! CSF1R_HUMAN-Phosphotyrosine699 relationship: transforms_into CCO:B0064555 ! CSF1R_HUMAN-Phosphotyrosine708 relationship: transforms_into CCO:B0064556 ! CSF1R_HUMAN-Phosphotyrosine809 [Term] id: CCO:B0054913 name: GRP_HUMAN def: "Gastrin-releasing peptide precursor" [UniProtKB:P07492] synonym: "GRP" EXACT [UniProtKB:P07492] xref: EMBL:AAA52611.1 xref: EMBL:AAA52612.1 xref: EMBL:AAA52613.1 xref: EMBL:AAH04488.1 xref: UniProtKB:P07491 xref: UniProtKB:P07492 xref: UniProtKB:P81553 xref: UniProtKB:Q14454 xref: UniProtKB:Q9BSY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018080 ! GRP_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0066633 ! GRP_HUMAN-Methionine amide50 [Term] id: CCO:B0054914 name: ADRB2_HUMAN def: "Beta-2 adrenergic receptor" [UniProtKB:P07550] synonym: "Beta-2 adrenoceptor" EXACT [UniProtKB:P07550] synonym: "Beta-2 adrenoreceptor" EXACT [UniProtKB:P07550] xref: EMBL:AAA88015.1 xref: EMBL:AAA88017.1 xref: EMBL:AAB82148.1 xref: EMBL:AAB82149.1 xref: EMBL:AAB82150.1 xref: EMBL:AAB82151.1 xref: EMBL:AAD48036.1 xref: EMBL:AAF17569.1 xref: EMBL:AAF20199.1 xref: EMBL:AAN01267.1 xref: EMBL:AAY88739.1 xref: EMBL:CAA28511.1 xref: EMBL:CAA68289.1 xref: UniProtKB:O14823 xref: UniProtKB:O14824 xref: UniProtKB:O14825 xref: UniProtKB:O14826 xref: UniProtKB:P07550 xref: UniProtKB:Q4JG18 xref: UniProtKB:Q8NEQ9 xref: UniProtKB:Q9UH95 xref: UniProtKB:Q9UHA1 xref: UniProtKB:Q9UMZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016924 ! ADRB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018487 ! eif2b1-adrb2-3 colocalization relationship: participates_in CCO:I0019489 ! eif2b1-adrb2-2 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000521 ! desensitization of G-protein coupled receptor protein signaling pathway by arrestin relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000713 ! activation of transmembrane receptor protein tyrosine kinase activity relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0065438 ! ADRB2_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0065440 ! ADRB2_HUMAN-Phosphoserine262 relationship: transforms_into CCO:B0065441 ! ADRB2_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0065442 ! ADRB2_HUMAN-Phosphoserine346 relationship: transforms_into CCO:B0065443 ! ADRB2_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0065444 ! ADRB2_HUMAN-Phosphoserine356 [Term] id: CCO:B0054915 name: HEXB_HUMAN def: "Beta-hexosaminidase subunit beta precursor" [UniProtKB:P07686] synonym: "Beta-N-acetylhexosaminidase subunit beta" EXACT [UniProtKB:P07686] synonym: "Cervical cancer proto-oncogene 7 protein" EXACT [UniProtKB:P07686] synonym: "EC 3.2.1.52" EXACT [UniProtKB:P07686] synonym: "HCC-7" EXACT [UniProtKB:P07686] synonym: "Hexosaminidase subunit B" EXACT [UniProtKB:P07686] synonym: "N-acetyl-beta-glucosaminidase subunit beta" EXACT [UniProtKB:P07686] xref: EMBL:AAA51828.1 xref: EMBL:AAA51829.1 xref: EMBL:AAA52645.1 xref: EMBL:AAA68620.1 xref: EMBL:AAH17378.1 xref: EMBL:AAM46114.1 xref: EMBL:AAP88921.1 xref: UniProtKB:P07686 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018125 ! HEXB_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000947 ! beta-N-acetylhexosaminidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005808 ! cation binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000177 ! acrosome relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:B0054916 name: CD3E_HUMAN def: "T-cell surface glycoprotein CD3 epsilon chain precursor" [UniProtKB:P07766] synonym: "CD1e antigen" EXACT [UniProtKB:P07766] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain" EXACT [UniProtKB:P07766] xref: EMBL:AAA52295.1 xref: EMBL:AAH49847.1 xref: EMBL:CAA27516.1 xref: UniProtKB:P07766 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017300 ! CD3E_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_function CCO:F0005691 ! T cell receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0064155 ! CD3E_HUMAN-Phosphotyrosine188 relationship: transforms_into CCO:B0064156 ! CD3E_HUMAN-Phosphotyrosine199 [Term] id: CCO:B0054917 name: UROM_HUMAN def: "Uromodulin precursor" [UniProtKB:P07911] synonym: "Tamm-Horsfall urinary glycoprotein" EXACT [UniProtKB:P07911] synonym: "THP" EXACT [UniProtKB:P07911] xref: EMBL:AAA36798.1 xref: EMBL:AAA36799.1 xref: EMBL:AAH35975.1 xref: EMBL:AAO64446.1 xref: EMBL:BAC87070.1 xref: UniProtKB:P07911 xref: UniProtKB:Q540J6 xref: UniProtKB:Q6ZS84 xref: UniProtKB:Q8IYG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020419 ! UMOD_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0054918 name: ZFY_HUMAN def: "Zinc finger Y-chromosomal protein" [UniProtKB:P08048] xref: EMBL:AAA61310.1 xref: EMBL:AAA72344.1 xref: EMBL:AAD15612.1 xref: EMBL:AAF21973.1 xref: EMBL:AAI14961.1 xref: EMBL:CAA33498.1 xref: UniProtKB:P08048 xref: UniProtKB:Q14021 xref: UniProtKB:Q15558 xref: UniProtKB:Q1RME9 xref: UniProtKB:Q96TF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020601 ! ZFY_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054919 name: OPSD_HUMAN def: "Rhodopsin" [UniProtKB:P08100] synonym: "Opsin-2" EXACT [UniProtKB:P08100] xref: EMBL:AAA97436.1 xref: EMBL:AAB35906.1 xref: EMBL:AAC31763.1 xref: EMBL:AAI12105.1 xref: EMBL:AAI12107.1 xref: EMBL:BAC05894.1 xref: EMBL:CAD97623.1 xref: UniProtKB:P08100 xref: UniProtKB:Q16414 xref: UniProtKB:Q2M249 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019052 ! RHO_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001112 ! rhodopsin mediated signaling pathway relationship: transforms_into CCO:B0068972 ! OPSD_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0068973 ! OPSD_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0068974 ! OPSD_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0068975 ! OPSD_HUMAN-Phosphoserine343 [Term] id: CCO:B0054920 name: CO1A2_HUMAN def: "Collagen alpha-2(I) chain precursor" [UniProtKB:P08123] synonym: "Alpha-2 type I collagen" EXACT [UniProtKB:P08123] xref: EMBL:AAA51844.1 xref: EMBL:AAA51846.1 xref: EMBL:AAA51850.1 xref: EMBL:AAA51887.1 xref: EMBL:AAA51996.1 xref: EMBL:AAA52053.1 xref: EMBL:AAA59994.1 xref: EMBL:AAA60041.1 xref: EMBL:AAA60356.1 xref: EMBL:AAB22020.2 xref: EMBL:AAB22126.1 xref: EMBL:AAB22761.1 xref: EMBL:AAB59374.1 xref: EMBL:AAB59577.1 xref: EMBL:AAB69977.1 xref: EMBL:AAB93981.1 xref: EMBL:AAH42586.1 xref: EMBL:AAH54498.1 xref: EMBL:BAA25383.1 xref: EMBL:CAA23761.1 xref: EMBL:CAA26320.1 xref: EMBL:CAA39142.1 xref: EMBL:CAA68709.1 xref: EMBL:CAA98969.1 xref: UniProtKB:P02464 xref: UniProtKB:P08123 xref: UniProtKB:Q13897 xref: UniProtKB:Q13997 xref: UniProtKB:Q13998 xref: UniProtKB:Q14038 xref: UniProtKB:Q14057 xref: UniProtKB:Q15177 xref: UniProtKB:Q15947 xref: UniProtKB:Q16480 xref: UniProtKB:Q16511 xref: UniProtKB:Q7Z5S6 xref: UniProtKB:Q9UEB6 xref: UniProtKB:Q9UEF9 xref: UniProtKB:Q9UM83 xref: UniProtKB:Q9UMI1 xref: UniProtKB:Q9UML5 xref: UniProtKB:Q9UMM6 xref: UniProtKB:Q9UPH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017421 ! COL1A2_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000205 ! collagen relationship: located_in CCO:C0000208 ! collagen type I relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0064431 ! CO1A2_HUMAN-Pyrrolidone carboxylic acid80 relationship: transforms_into CCO:B0064432 ! CO1A2_HUMAN-Allysine84 relationship: transforms_into CCO:B0064433 ! CO1A2_HUMAN-Hydroxyproline420 relationship: transforms_into CCO:B0064434 ! CO1A2_HUMAN-Hydroxyproline441 relationship: transforms_into CCO:B0064435 ! CO1A2_HUMAN-Hydroxyproline444 [Term] id: CCO:B0054921 name: TNR16_HUMAN def: "Tumor necrosis factor receptor superfamily member 16 precursor" [UniProtKB:P08138] synonym: "CD271 antigen" EXACT [UniProtKB:P08138] synonym: "Gp80-LNGFR" EXACT [UniProtKB:P08138] synonym: "Low affinity neurotrophin receptor p75NTR" EXACT [UniProtKB:P08138] synonym: "Low-affinity nerve growth factor receptor" EXACT [UniProtKB:P08138] synonym: "NGF receptor" EXACT [UniProtKB:P08138] synonym: "p75 ICD" EXACT [UniProtKB:P08138] xref: EMBL:AAA36363.1 xref: EMBL:AAB59544.1 xref: EMBL:AAH50309.1 xref: UniProtKB:P08138 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020312 ! NGFR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001357 ! neurotrophin receptor activity relationship: has_function CCO:F0001360 ! death receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007336 ! nerve growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054922 name: GLI1_HUMAN def: "Zinc finger protein GLI1" [UniProtKB:P08151] synonym: "Glioma-associated oncogene" EXACT [UniProtKB:P08151] synonym: "Oncogene GLI" EXACT [UniProtKB:P08151] xref: EMBL:AAH13000.1 xref: EMBL:AAM13391.1 xref: EMBL:CAA30297.1 xref: UniProtKB:P08151 xref: UniProtKB:Q8TDN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017927 ! GLI1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015964 ! stk36-gli1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000826 ! regulation of smoothened signaling pathway relationship: participates_in CCO:P0001210 ! smoothened signaling pathway in regulation of granule cell precursor cell proliferation relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054923 name: ACM2_HUMAN def: "Muscarinic acetylcholine receptor M2" [UniProtKB:P08172] xref: EMBL:AAA51570.1 xref: EMBL:AAH95547.1 xref: EMBL:AAI06742.1 xref: EMBL:AAI06743.1 xref: EMBL:AAM18939.1 xref: EMBL:BAA94476.1 xref: EMBL:CAA33335.1 xref: UniProtKB:P08172 xref: UniProtKB:Q4VBK6 xref: UniProtKB:Q9P1X9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016899 ! CHRM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000742 ! muscarinic acetylcholine receptor, phospholipase C activating pathway relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: transforms_into CCO:B0065378 ! ACM2_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0065380 ! ACM2_HUMAN-Phosphothreonine446 relationship: transforms_into CCO:B0065381 ! ACM2_HUMAN-Phosphothreonine450 relationship: transforms_into CCO:B0065382 ! ACM2_HUMAN-Phosphothreonine465 [Term] id: CCO:B0054924 name: ACM4_HUMAN def: "Muscarinic acetylcholine receptor M4" [UniProtKB:P08173] xref: EMBL:AAA51571.2 xref: EMBL:AAH95546.1 xref: EMBL:AAI19776.1 xref: EMBL:AAI19818.1 xref: EMBL:AAM18941.1 xref: EMBL:CAA33336.1 xref: UniProtKB:P08173 xref: UniProtKB:Q0VD60 xref: UniProtKB:Q4VBK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016901 ! CHRM4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: transforms_into CCO:B0065384 ! ACM4_HUMAN-Phosphothreonine463 relationship: transforms_into CCO:B0065385 ! ACM4_HUMAN-Phosphothreonine477 [Term] id: CCO:B0054925 name: MCR_HUMAN def: "Mineralocorticoid receptor" [UniProtKB:P08235] synonym: "MR" EXACT [UniProtKB:P08235] synonym: "Nuclear receptor subfamily 3 group C member 2" EXACT [UniProtKB:P08235] xref: EMBL:AAA59571.1 xref: EMBL:AAC63513.1 xref: EMBL:CAC67405.1 xref: EMBL:CAC67406.1 xref: UniProtKB:P08235 xref: UniProtKB:Q96KQ8 xref: UniProtKB:Q96KQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018592 ! NR3C2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054926 name: ELNE_HUMAN def: "Leukocyte elastase precursor" [UniProtKB:P08246] synonym: "Bone marrow serine protease" EXACT [UniProtKB:P08246] synonym: "EC 3.4.21.37" EXACT [UniProtKB:P08246] synonym: "Elastase-2" EXACT [UniProtKB:P08246] synonym: "HLE" EXACT [UniProtKB:P08246] synonym: "Human leukocyte elastase" EXACT [UniProtKB:P08246] synonym: "Medullasin" EXACT [UniProtKB:P08246] synonym: "Neutrophil elastase" EXACT [UniProtKB:P08246] synonym: "PMN elastase" EXACT [UniProtKB:P08246] xref: EMBL:AAA35792.1 xref: EMBL:AAA36173.1 xref: EMBL:AAA36359.1 xref: EMBL:AAA52378.1 xref: EMBL:AAH74816.1 xref: EMBL:AAH74817.1 xref: EMBL:AAS89303.1 xref: EMBL:BAA00128.1 xref: EMBL:CAA29299.1 xref: EMBL:CAA29300.1 xref: EMBL:CAA68537.1 xref: UniProtKB:P08246 xref: UniProtKB:P09649 xref: UniProtKB:Q6B0D9 xref: UniProtKB:Q6LDP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017691 ! ELA2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001847 ! bacterial binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004221 ! cytokine binding relationship: has_function CCO:F0005704 ! elastase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0018559 ! serpina1-ela2-1 direct interaction relationship: participates_in CCO:P0002271 ! negative regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002356 ! negative regulation of interleukin-8 biosynthetic process relationship: participates_in CCO:P0002357 ! positive regulation of interleukin-8 biosynthetic process relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation [Term] id: CCO:B0054927 name: PLEK_HUMAN def: "Pleckstrin" [UniProtKB:P08567] synonym: "Platelet p47 protein" EXACT [UniProtKB:P08567] xref: EMBL:AAH18549.1 xref: EMBL:AAX93121.1 xref: EMBL:CAA30564.1 xref: EMBL:CAG46876.1 xref: UniProtKB:P08567 xref: UniProtKB:Q53SU8 xref: UniProtKB:Q6FGM8 xref: UniProtKB:Q8WV81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019443 ! PLEK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069413 ! PLEK_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0069414 ! PLEK_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0069415 ! PLEK_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0069416 ! PLEK_HUMAN-Phosphoserine197 [Term] id: CCO:B0054928 name: CD14_HUMAN def: "Monocyte differentiation antigen CD14 precursor" [UniProtKB:P08571] synonym: "CD14 antigen" EXACT [UniProtKB:P08571] synonym: "Myeloid cell-specific leucine-rich glycoprotein" EXACT [UniProtKB:P08571] xref: EMBL:AAA51930.1 xref: EMBL:AAC83816.1 xref: EMBL:AAH10507.1 xref: EMBL:AAL02401.1 xref: EMBL:CAA29999.1 xref: EMBL:CAA31711.1 xref: UniProtKB:P08571 xref: UniProtKB:Q96FR6 xref: UniProtKB:Q96L99 xref: UniProtKB:Q9UNS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017286 ! CD14_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003032 ! peptidoglycan receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0054929 name: ADRB1_HUMAN def: "Beta-1 adrenergic receptor" [UniProtKB:P08588] synonym: "Beta-1 adrenoceptor" EXACT [UniProtKB:P08588] synonym: "Beta-1 adrenoreceptor" EXACT [UniProtKB:P08588] xref: EMBL:AAA51667.1 xref: EMBL:AAD53696.1 xref: EMBL:AAD53697.1 xref: EMBL:AAS66983.1 xref: UniProtKB:P08588 xref: UniProtKB:Q9UKG7 xref: UniProtKB:Q9UKG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016923 ! ADRB1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001281 ! beta-adrenergic receptor activity relationship: has_function CCO:F0001282 ! beta1-adrenergic receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016326 ! magi1-adrb1-1 direct interaction relationship: participates_in CCO:I0016327 ! magi2-adrb1-2 direct interaction relationship: participates_in CCO:I0016328 ! magi2-adrb1-1 direct interaction relationship: participates_in CCO:I0016329 ! gopc-adrb1-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: transforms_into CCO:B0065436 ! ADRB1_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0065437 ! ADRB1_HUMAN-Phosphoserine412 [Term] id: CCO:B0054930 name: RU17_HUMAN def: "U1 small nuclear ribonucleoprotein 70 kDa" [UniProtKB:P08621] synonym: "snRNP70" EXACT [UniProtKB:P08621] synonym: "U1 snRNP 70 kDa" EXACT [UniProtKB:P08621] synonym: "U1-70K" EXACT [UniProtKB:P08621] xref: EMBL:AAA03001.1 xref: EMBL:AAA36571.1 xref: EMBL:AAA36572.1 xref: EMBL:AAA36573.1 xref: EMBL:AAH01315.1 xref: EMBL:CAA28352.1 xref: EMBL:CAA29960.1 xref: EMBL:CAA29961.1 xref: EMBL:CAA29963.1 xref: EMBL:CAA29964.1 xref: EMBL:CAA29965.1 xref: EMBL:CAA29966.1 xref: EMBL:CAA30303.1 xref: EMBL:CAA30304.1 xref: EMBL:CAA30305.1 xref: EMBL:CAA59278.1 xref: EMBL:CAB55969.1 xref: UniProtKB:P08621 xref: UniProtKB:P78493 xref: UniProtKB:P78494 xref: UniProtKB:Q15364 xref: UniProtKB:Q15686 xref: UniProtKB:Q15687 xref: UniProtKB:Q15689 xref: UniProtKB:Q99377 xref: UniProtKB:Q9UE45 xref: UniProtKB:Q9UE46 xref: UniProtKB:Q9UE47 xref: UniProtKB:Q9UE48 xref: UniProtKB:Q9UFQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019813 ! SNRP70_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017449 ! cep63-snrp70 physical interaction relationship: participates_in CCO:P0002221 ! regulation of RNA splicing relationship: transforms_into CCO:B0070262 ! RU17_HUMAN-Phosphotyrosine126 relationship: transforms_into CCO:B0070263 ! RU17_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0070264 ! RU17_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0070265 ! RU17_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0070266 ! RU17_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0070267 ! RU17_HUMAN-Phosphoserine410 [Term] id: CCO:B0054931 name: IL3_HUMAN def: "Interleukin-3 precursor" [UniProtKB:P08700] synonym: "Hematopoietic growth factor" EXACT [UniProtKB:P08700] synonym: "IL-3" EXACT [UniProtKB:P08700] synonym: "Mast cell growth factor" EXACT [UniProtKB:P08700] synonym: "MCGF" EXACT [UniProtKB:P08700] synonym: "Multipotential colony-stimulating factor" EXACT [UniProtKB:P08700] synonym: "P-cell-stimulating factor" EXACT [UniProtKB:P08700] xref: EMBL:AAA35725.1 xref: EMBL:AAA59146.1 xref: EMBL:AAA59147.1 xref: EMBL:AAC08706.1 xref: EMBL:AAH66272.1 xref: EMBL:AAH69472.1 xref: EMBL:AAK38378.1 xref: UniProtKB:P08700 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018263 ! IL3_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001437 ! interleukin-3 receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002088 ! positive regulation of tyrosine phosphorylation of Stat5 protein relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0054932 name: IBP1_HUMAN def: "Insulin-like growth factor-binding protein 1 precursor" [UniProtKB:P08833] synonym: "IBP-1" EXACT [UniProtKB:P08833] synonym: "IGF-binding protein 1" EXACT [UniProtKB:P08833] synonym: "IGFBP-1" EXACT [UniProtKB:P08833] synonym: "Placental protein 12" EXACT [UniProtKB:P08833] synonym: "PP12" EXACT [UniProtKB:P08833] xref: EMBL:AAA52540.1 xref: EMBL:AAA52542.1 xref: EMBL:AAA52783.1 xref: EMBL:AAA52784.1 xref: EMBL:AAA52785.1 xref: EMBL:AAH35263.2 xref: EMBL:AAQ96599.1 xref: EMBL:AAV38491.1 xref: EMBL:CAA30942.1 xref: EMBL:CAA31771.1 xref: EMBL:CAA33110.1 xref: EMBL:CAA68770.1 xref: UniProtKB:P08833 xref: UniProtKB:Q8IYP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018207 ! IGFBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066997 ! IBP1_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0066998 ! IBP1_HUMAN-Phosphoserine144 relationship: transforms_into CCO:B0066999 ! IBP1_HUMAN-Phosphoserine194 [Term] id: CCO:B0054933 name: IL6RA_HUMAN def: "Interleukin-6 receptor subunit alpha precursor" [UniProtKB:P08887] synonym: "CD126 antigen" EXACT [UniProtKB:P08887] synonym: "gp80" EXACT [UniProtKB:P08887] synonym: "IL-6R 1" EXACT [UniProtKB:P08887] synonym: "IL-6R-alpha" EXACT [UniProtKB:P08887] synonym: "Membrane glycoprotein 80" EXACT [UniProtKB:P08887] xref: EMBL:AAC60635.1 xref: EMBL:AAH89410.1 xref: EMBL:BAD97302.1 xref: EMBL:CAA31312.1 xref: EMBL:CAA41231.1 xref: EMBL:CAH72853.1 xref: UniProtKB:P08887 xref: UniProtKB:Q16202 xref: UniProtKB:Q53EQ7 xref: UniProtKB:Q5FWG2 xref: UniProtKB:Q5VZ23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018268 ! IL6R_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001262 ! interleukin-6 receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000453 ! interleukin-6 receptor complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: participates_in CCO:I0016013 ! il6r-arts1 physical interaction relationship: participates_in CCO:I0018118 ! il6-il6r-1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0054934 name: 5HT1A_HUMAN def: "5-hydroxytryptamine receptor 1A" [UniProtKB:P08908] synonym: "5-HT-1A" EXACT [UniProtKB:P08908] synonym: "5-HT1A" EXACT [UniProtKB:P08908] synonym: "G-21" EXACT [UniProtKB:P08908] synonym: "Serotonin receptor 1A" EXACT [UniProtKB:P08908] xref: EMBL:AAA36440.1 xref: EMBL:AAA66493.1 xref: EMBL:AAH69159.1 xref: EMBL:AAM21125.1 xref: EMBL:BAA94488.1 xref: EMBL:CAA31908.1 xref: EMBL:CAA40962.1 xref: EMBL:CAA77560.1 xref: UniProtKB:P08908 xref: UniProtKB:Q6LAE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016850 ! HTR1A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0054935 name: ABHD2_HUMAN def: "Abhydrolase domain-containing protein 2" [UniProtKB:P08910] synonym: "EC 3.1.1.-" EXACT [UniProtKB:P08910] synonym: "Lung alpha/beta hydrolase 2" EXACT [UniProtKB:P08910] synonym: "Protein PHPS1-2" EXACT [UniProtKB:P08910] xref: EMBL:AAH19248.1 xref: EMBL:AAH90052.1 xref: EMBL:AAQ12021.1 xref: EMBL:BAD96561.1 xref: EMBL:BAD96803.1 xref: EMBL:CAA30976.1 xref: UniProtKB:P08910 xref: UniProtKB:Q53G48 xref: UniProtKB:Q53GU0 xref: UniProtKB:Q5FVD9 xref: UniProtKB:Q8TC79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016874 ! ABHD2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000566 ! carboxylesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001259 ! negative regulation of cell migration [Term] id: CCO:B0054936 name: ACM5_HUMAN def: "Muscarinic acetylcholine receptor M5" [UniProtKB:P08912] xref: EMBL:AAA51569.1 xref: EMBL:AAB95158.1 xref: EMBL:AAK68116.1 xref: EMBL:AAM18942.1 xref: EMBL:BAB91222.1 xref: UniProtKB:P08912 xref: UniProtKB:Q96RG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016902 ! CHRM5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000735 ! muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: transforms_into CCO:B0065387 ! ACM5_HUMAN-Phosphothreonine505 [Term] id: CCO:B0054937 name: ADA2A_HUMAN def: "Alpha-2A adrenergic receptor" [UniProtKB:P08913] synonym: "Alpha-2 adrenergic receptor subtype C10" EXACT [UniProtKB:P08913] synonym: "Alpha-2A adrenoceptor" EXACT [UniProtKB:P08913] synonym: "Alpha-2A adrenoreceptor" EXACT [UniProtKB:P08913] synonym: "Alpha-2AAR" EXACT [UniProtKB:P08913] xref: EMBL:AAA51664.1 xref: EMBL:AAA51665.1 xref: EMBL:AAF91441.1 xref: EMBL:AAG00447.2 xref: EMBL:AAH35047.1 xref: EMBL:AAH50414.4 xref: EMBL:AAK01634.1 xref: EMBL:AAK26743.1 xref: EMBL:AAK51162.1 xref: EMBL:AAZ73101.1 xref: EMBL:ABB72683.1 xref: EMBL:CAH72817.1 xref: UniProtKB:P08913 xref: UniProtKB:Q2I8G2 xref: UniProtKB:Q2XN99 xref: UniProtKB:Q86TH8 xref: UniProtKB:Q9BZK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016907 ! ADRA2A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001280 ! alpha2-adrenergic receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002867 ! potassium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0065399 ! ADA2A_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0065400 ! ADA2A_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0065401 ! ADA2A_HUMAN-Phosphoserine299 [Term] id: CCO:B0054938 name: NMB_HUMAN def: "Neuromedin-B precursor" [UniProtKB:P08949] xref: EMBL:AAA59934.1 xref: EMBL:AAH07407.1 xref: EMBL:AAH07431.1 xref: EMBL:AAH08603.1 xref: UniProtKB:P08949 xref: UniProtKB:Q96A06 xref: UniProtKB:Q96HH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018807 ! NMB_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0068749 ! NMB_HUMAN-Methionine amide56 [Term] id: CCO:B0054939 name: CD63_HUMAN def: "CD63 antigen" [UniProtKB:P08962] synonym: "CD63 antigen" EXACT [UniProtKB:P08962] synonym: "Granulophysin" EXACT [UniProtKB:P08962] synonym: "Lamp-3" EXACT [UniProtKB:P08962] synonym: "Lysosomal-associated membrane protein 3" EXACT [UniProtKB:P08962] synonym: "Melanoma-associated antigen ME491" EXACT [UniProtKB:P08962] synonym: "Ocular melanoma-associated antigen" EXACT [UniProtKB:P08962] synonym: "OMA81H" EXACT [UniProtKB:P08962] synonym: "Tetraspanin-30" EXACT [UniProtKB:P08962] synonym: "Tspan-30" EXACT [UniProtKB:P08962] xref: EMBL:AAA63235.1 xref: EMBL:AAB21617.1 xref: EMBL:AAH02349.1 xref: EMBL:AAH13017.1 xref: EMBL:AAP35736.1 xref: EMBL:CAA30792.1 xref: EMBL:CAA44519.1 xref: UniProtKB:P08962 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017306 ! CD63_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: participates_in CCO:P0002557 ! positive regulation of endocytosis [Term] id: CCO:B0054940 name: PO2F2_HUMAN def: "POU domain, class 2, transcription factor 2" [UniProtKB:P09086] synonym: "Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2" EXACT [UniProtKB:P09086] synonym: "Oct-2" EXACT [UniProtKB:P09086] synonym: "Octamer-binding transcription factor 2" EXACT [UniProtKB:P09086] synonym: "OTF-2" EXACT [UniProtKB:P09086] xref: EMBL:AAA36389.1 xref: EMBL:AAA36732.1 xref: EMBL:AAA59978.1 xref: EMBL:AAH06101.1 xref: EMBL:AAP36106.1 xref: EMBL:CAA32039.1 xref: EMBL:CAA32040.1 xref: EMBL:CAA37562.1 xref: EMBL:CAA37565.1 xref: EMBL:CAA56933.1 xref: UniProtKB:P09086 xref: UniProtKB:Q16648 xref: UniProtKB:Q7M4M8 xref: UniProtKB:Q9BRS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019461 ! POU2F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054941 name: DOPO_HUMAN def: "Dopamine beta-hydroxylase" [UniProtKB:P09172] synonym: "Dopamine beta-monooxygenase" EXACT [UniProtKB:P09172] synonym: "EC 1.14.17.1" EXACT [UniProtKB:P09172] xref: EMBL:AAH17174.1 xref: EMBL:CAA31631.1 xref: EMBL:CAA31632.1 xref: EMBL:CAA68285.1 xref: EMBL:CAI13354.2 xref: UniProtKB:P09172 xref: UniProtKB:Q5T381 xref: UniProtKB:Q96AG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017605 ! DBH_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0000897 ! dopamine beta-monooxygenase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001656 ! chromaffin granule relationship: participates_in CCO:P0000887 ! cellular process [Term] id: CCO:B0054942 name: LEG1_HUMAN def: "Galectin-1" [UniProtKB:P09382] synonym: "14 kDa lectin" EXACT [UniProtKB:P09382] synonym: "Beta-galactoside-binding lectin L-14-I" EXACT [UniProtKB:P09382] synonym: "Galaptin" EXACT [UniProtKB:P09382] synonym: "HBL" EXACT [UniProtKB:P09382] synonym: "HPL" EXACT [UniProtKB:P09382] synonym: "Lactose-binding lectin 1" EXACT [UniProtKB:P09382] synonym: "Lectin galactoside-binding soluble 1" EXACT [UniProtKB:P09382] synonym: "Putative MAPK-activating protein PM12" EXACT [UniProtKB:P09382] synonym: "S-Lac lectin 1" EXACT [UniProtKB:P09382] xref: EMBL:AAA36170.1 xref: EMBL:AAB00777.1 xref: EMBL:AAH01693.1 xref: EMBL:AAH20675.1 xref: EMBL:AAP35421.1 xref: EMBL:BAC77389.1 xref: EMBL:CAA32938.1 xref: EMBL:CAA33328.1 xref: EMBL:CAB42897.1 xref: EMBL:CAG30397.1 xref: UniProtKB:P09382 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018470 ! LGALS1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0067609 ! LEG1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0054943 name: STP1_HUMAN def: "Spermatid nuclear transition protein 1" [UniProtKB:P09430] synonym: "STP-1" EXACT [UniProtKB:P09430] synonym: "TP-1" EXACT [UniProtKB:P09430] xref: EMBL:AAA61202.1 xref: EMBL:AAH29516.1 xref: EMBL:CAA30774.1 xref: UniProtKB:P09430 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020074 ! TNP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0054944 name: SPRC_HUMAN def: "SPARC precursor" [UniProtKB:P09486] synonym: "Basement-membrane protein 40" EXACT [UniProtKB:P09486] synonym: "BM-40" EXACT [UniProtKB:P09486] synonym: "ON" EXACT [UniProtKB:P09486] synonym: "Osteonectin" EXACT [UniProtKB:P09486] synonym: "Secreted protein acidic and rich in cysteine" EXACT [UniProtKB:P09486] xref: EMBL:AAA60570.1 xref: EMBL:AAA60993.1 xref: EMBL:AAH04974.1 xref: EMBL:AAH08011.1 xref: EMBL:AAH72457.1 xref: EMBL:CAA68724.1 xref: UniProtKB:P09486 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020018 ! SPARC_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0054945 name: WNT2_HUMAN def: "Protein Wnt-2 precursor" [UniProtKB:P09544] synonym: "Int-1-related protein" EXACT [UniProtKB:P09544] synonym: "IRP protein" EXACT [UniProtKB:P09544] xref: EMBL:AAB67043.1 xref: EMBL:AAD28351.1 xref: EMBL:AAH29854.1 xref: EMBL:AAH78170.1 xref: EMBL:AAV38415.1 xref: EMBL:CAA30725.1 xref: UniProtKB:P09544 xref: UniProtKB:Q75N05 xref: UniProtKB:Q9UDP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020486 ! WNT2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_function CCO:F0008027 ! nitric-oxide synthase binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization [Term] id: CCO:B0054946 name: CD7_HUMAN def: "T-cell antigen CD7 precursor" [UniProtKB:P09564] synonym: "CD7 antigen" EXACT [UniProtKB:P09564] synonym: "GP40" EXACT [UniProtKB:P09564] synonym: "Leu-9" EXACT [UniProtKB:P09564] synonym: "T-cell leukemia antigen" EXACT [UniProtKB:P09564] synonym: "TP41" EXACT [UniProtKB:P09564] xref: EMBL:AAA51953.1 xref: EMBL:AAH09293.1 xref: EMBL:AAH13297.1 xref: EMBL:AAP35342.1 xref: EMBL:BAA00646.1 xref: EMBL:CAA29546.1 xref: UniProtKB:P09564 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017310 ! CD7_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0054947 name: HMOX1_HUMAN def: "Heme oxygenase 1" [UniProtKB:P09601] synonym: "EC 1.14.99.3" EXACT [UniProtKB:P09601] synonym: "HO-1" EXACT [UniProtKB:P09601] xref: EMBL:AAA50403.1 xref: EMBL:AAR23262.1 xref: EMBL:CAA30045.1 xref: EMBL:CAA32886.1 xref: EMBL:CAB05109.1 xref: EMBL:CAG30391.1 xref: UniProtKB:P09601 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018145 ! HMOX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000503 ! endothelial cell proliferation relationship: participates_in CCO:P0000554 ! negative regulation of leukocyte migration relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002181 ! negative regulation of mast cell degranulation relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: participates_in CCO:P0002250 ! regulation of transcription from RNA polymerase II promoter in response to oxidative stress relationship: participates_in CCO:P0002272 ! positive regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis relationship: participates_in CCO:P0003021 ! regulation of transcription factor activity relationship: transforms_into CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 [Term] id: CCO:B0054948 name: GIP_HUMAN def: "Gastric inhibitory polypeptide precursor" [UniProtKB:P09681] synonym: "GIP" EXACT [UniProtKB:P09681] synonym: "Glucose-dependent insulinotropic polypeptide" EXACT [UniProtKB:P09681] xref: EMBL:AAA53192.1 xref: EMBL:AAA88043.1 xref: EMBL:AAH69100.1 xref: EMBL:AAH69663.1 xref: EMBL:AAH69686.1 xref: EMBL:AAH69746.1 xref: EMBL:AAH96146.1 xref: EMBL:AAH96147.1 xref: EMBL:AAH96148.1 xref: EMBL:AAH96149.1 xref: UniProtKB:P09681 xref: UniProtKB:Q4VB42 xref: UniProtKB:Q6NTD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017924 ! GIP_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054949 name: CD3G_HUMAN def: "T-cell surface glycoprotein CD3 gamma chain precursor" [UniProtKB:P09693] synonym: "CD3g antigen" EXACT [UniProtKB:P09693] synonym: "T-cell receptor T3 gamma chain" EXACT [UniProtKB:P09693] xref: EMBL:AAI13831.1 xref: EMBL:CAA27764.1 xref: EMBL:CAA29428.1 xref: UniProtKB:P09693 xref: UniProtKB:Q2HIZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017301 ! CD3G_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0064157 ! CD3G_HUMAN-Phosphoserine145 relationship: transforms_into CCO:B0064158 ! CD3G_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0064159 ! CD3G_HUMAN-Phosphotyrosine160 relationship: transforms_into CCO:B0064160 ! CD3G_HUMAN-Phosphotyrosine171 [Term] id: CCO:B0054950 name: TACD2_HUMAN def: "Tumor-associated calcium signal transducer 2 precursor" [UniProtKB:P09758] synonym: "Cell surface glycoprotein Trop-2" EXACT [UniProtKB:P09758] synonym: "Pancreatic carcinoma marker protein GA733-1" EXACT [UniProtKB:P09758] xref: EMBL:AAA52505.1 xref: EMBL:AAH09409.1 xref: EMBL:CAA31781.1 xref: EMBL:CAA54799.1 xref: EMBL:CAA54801.1 xref: UniProtKB:P09758 xref: UniProtKB:Q15658 xref: UniProtKB:Q96QD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020127 ! TACSTD2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0071081 ! TACD2_HUMAN-Phosphoserine322 [Term] id: CCO:B0054951 name: IFI6_HUMAN def: "Interferon alpha-inducible protein 6 precursor" [UniProtKB:P09912] synonym: "Ifi-6-16" EXACT [UniProtKB:P09912] synonym: "Interferon-induced protein 6-16" EXACT [UniProtKB:P09912] xref: EMBL:AAC50159.1 xref: EMBL:AAC50160.1 xref: EMBL:AAC50161.1 xref: EMBL:AAH11601.1 xref: EMBL:AAH15603.1 xref: EMBL:AAP35496.1 xref: EMBL:CAA26322.1 xref: UniProtKB:P09912 xref: UniProtKB:Q13141 xref: UniProtKB:Q13142 xref: UniProtKB:Q969M8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018232 ! IFI6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000479 ! release of cytochrome c from mitochondria relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: participates_in CCO:P0003162 ! negative regulation of mitochondrial depolarization [Term] id: CCO:B0054952 name: CSF3_HUMAN def: "Granulocyte colony-stimulating factor precursor" [UniProtKB:P09919] synonym: "Filgrastim" EXACT [UniProtKB:P09919] synonym: "G-CSF" EXACT [UniProtKB:P09919] synonym: "Lenograstim" EXACT [UniProtKB:P09919] synonym: "Pluripoietin" EXACT [UniProtKB:P09919] xref: EMBL:AAA03056.1 xref: EMBL:AAA35882.1 xref: EMBL:AAK62469.1 xref: EMBL:CAA27168.1 xref: EMBL:CAA27290.1 xref: EMBL:CAA27291.1 xref: UniProtKB:P09919 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017476 ! CSF3_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001432 ! granulocyte colony-stimulating factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0054953 name: RB40L_HUMAN def: "Ras-related protein Rab-40A-like" [UniProtKB:P0C0E4] synonym: "Ras-like GTPase" EXACT [UniProtKB:P0C0E4] xref: EMBL:AAI01170.1 xref: EMBL:AAI01171.1 xref: EMBL:AAI01172.1 xref: EMBL:AAI01173.1 xref: EMBL:CAB09136.1 xref: UniProtKB:P0C0E4 xref: UniProtKB:Q495H3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019643 ! RAB40AL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0054954 name: NPS_HUMAN def: "Neuropeptide S precursor" [UniProtKB:P0C0P6] xref: UniProtKB:P0C0P6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018839 ! NPS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0054955 name: OR4A8_HUMAN def: "Olfactory receptor 4A8" [UniProtKB:P0C604] synonym: "Olfactory receptor OR11-110" EXACT [UniProtKB:P0C604] xref: UniProtKB:P0C604 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019133 ! OR4A8P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054956 name: O5AL1_HUMAN def: "Olfactory receptor 5AL1" [UniProtKB:P0C617] synonym: "Olfactory receptor OR11-184" EXACT [UniProtKB:P0C617] xref: UniProtKB:P0C617 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019029 ! OR5AL1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054957 name: OR4Q2_HUMAN def: "Olfactory receptor 4Q2" [UniProtKB:P0C623] synonym: "olfactory receptor OR14-21" EXACT [UniProtKB:P0C623] xref: UniProtKB:P0C623 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019171 ! OR4Q2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054958 name: OR5G3_HUMAN def: "Olfactory receptor 5G3" [UniProtKB:P0C626] synonym: "Olfactory receptor OR11-213" EXACT [UniProtKB:P0C626] xref: UniProtKB:P0C626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019186 ! OR5G3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054959 name: O10J4_HUMAN def: "Olfactory receptor 10J4" [UniProtKB:P0C629] xref: UniProtKB:P0C629 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018921 ! OR10J4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054960 name: OR4E1_HUMAN def: "Olfactory receptor 4E1" [UniProtKB:P0C645] synonym: "Olfactory receptor OR14-43" EXACT [UniProtKB:P0C645] xref: UniProtKB:P0C645 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019150 ! OR4E1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054961 name: O52Z1_HUMAN def: "Olfactory receptor 52Z1" [UniProtKB:P0C646] xref: UniProtKB:P0C646 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019024 ! OR52Z1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054962 name: GLP1_HUMAN def: "GATA-like protein 1" [UniProtKB:P0C6A0] synonym: "GLP-1" EXACT [UniProtKB:P0C6A0] xref: UniProtKB:P0C6A0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017931 ! GLP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054963 name: RHF2B_HUMAN def: "Rhox homeobox family member 2B" [UniProtKB:P0C7M4] xref: EMBL:CAC36517.1 xref: UniProtKB:P0C7M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019713 ! RHOXF2B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0054964 name: OR9G9_HUMAN def: "Olfactory receptor 9G9" [UniProtKB:P0C7N8] xref: EMBL:EAW73723.1 xref: UniProtKB:P0C7N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019238 ! OR9G9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054965 name: GLI2_HUMAN def: "Zinc finger protein GLI2" [UniProtKB:P10070] synonym: "Tax helper protein" EXACT [UniProtKB:P10070] xref: EMBL:AAA35898.1 xref: EMBL:AAY87165.1 xref: EMBL:BAA03568.1 xref: EMBL:BAA03569.1 xref: EMBL:BAA25665.1 xref: EMBL:BAA25666.1 xref: EMBL:BAA25667.1 xref: EMBL:BAA25668.1 xref: UniProtKB:O60252 xref: UniProtKB:O60253 xref: UniProtKB:O60254 xref: UniProtKB:O60255 xref: UniProtKB:P10070 xref: UniProtKB:Q15590 xref: UniProtKB:Q15591 xref: UniProtKB:Q4JHT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017928 ! GLI2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001156 ! smoothened signaling pathway involved in ventral spinal cord interneuron specification relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0054966 name: HKR1_HUMAN def: "Krueppel-related zinc finger protein 1" [UniProtKB:P10072] synonym: "Protein HKR1" EXACT [UniProtKB:P10072] xref: EMBL:AAH04513.2 xref: EMBL:AAH17256.1 xref: EMBL:BAA86058.1 xref: EMBL:EAW56722.1 xref: UniProtKB:A8MRS7 xref: UniProtKB:P10072 xref: UniProtKB:Q6PJD0 xref: UniProtKB:Q9BSW9 xref: UniProtKB:Q9UM09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018134 ! HKR1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054967 name: ZSC22_HUMAN def: "Zinc finger and SCAN domain-containing protein 22" [UniProtKB:P10073] synonym: "Krueppel-related zinc finger protein 2" EXACT [UniProtKB:P10073] synonym: "Protein HKR2" EXACT [UniProtKB:P10073] synonym: "Zinc finger protein 50" EXACT [UniProtKB:P10073] xref: EMBL:AAA61318.1 xref: EMBL:AAI01631.1 xref: EMBL:AAI12278.1 xref: EMBL:BAC87588.1 xref: EMBL:CAD97822.1 xref: UniProtKB:P10073 xref: UniProtKB:Q15922 xref: UniProtKB:Q7Z3L8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021004 ! ZSCAN22_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072278 ! ZSC22_HUMAN-Phosphoserine32 [Term] id: CCO:B0054968 name: ZBT48_HUMAN def: "Zinc finger and BTB domain-containing protein 48" [UniProtKB:P10074] synonym: "Krueppel-related zinc finger protein 3" EXACT [UniProtKB:P10074] synonym: "Protein HKR3" EXACT [UniProtKB:P10074] xref: EMBL:AAA35989.1 xref: EMBL:AAA65124.1 xref: EMBL:AAB08973.1 xref: EMBL:AAH13573.1 xref: EMBL:CAI16079.1 xref: UniProtKB:P10074 xref: UniProtKB:Q5SY19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020563 ! ZBTB48_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015145 ! hkr3-q96br9 physical interaction relationship: participates_in CCO:I0015217 ! c7orf34-hkr3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054969 name: PYY_HUMAN def: "Peptide YY precursor" [UniProtKB:P10082] synonym: "Peptide tyrosine tyrosine" EXACT [UniProtKB:P10082] synonym: "PYY" EXACT [UniProtKB:P10082] synonym: "PYY-I" EXACT [UniProtKB:P10082] xref: EMBL:AAA36433.1 xref: EMBL:AAH41057.1 xref: EMBL:BAA02997.1 xref: EMBL:BAA02998.1 xref: EMBL:BAA03000.1 xref: EMBL:BAA03002.1 xref: EMBL:CAG46926.1 xref: UniProtKB:P10082 xref: UniProtKB:Q5U5Q6 xref: UniProtKB:Q6FGH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019565 ! PYY_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0069654 ! PYY_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0069655 ! PYY_HUMAN-Tyrosine amide64 [Term] id: CCO:B0054970 name: CALCB_HUMAN def: "Calcitonin gene-related peptide 2 precursor" [UniProtKB:P10092] synonym: "Beta-type CGRP" EXACT [UniProtKB:P10092] synonym: "Calcitonin gene-related peptide II" EXACT [UniProtKB:P10092] synonym: "CGRP-II" EXACT [UniProtKB:P10092] xref: EMBL:AAH92468.1 xref: EMBL:CAA26249.1 xref: EMBL:CAC05295.1 xref: UniProtKB:P10092 xref: UniProtKB:Q569I0 xref: UniProtKB:Q9UCN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017216 ! CALCB_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064055 ! CALCB_HUMAN-Phenylalanine amide118 [Term] id: CCO:B0054971 name: GRAB_HUMAN def: "Granzyme B precursor" [UniProtKB:P10144] synonym: "C11" EXACT [UniProtKB:P10144] synonym: "Cathepsin G-like 1" EXACT [UniProtKB:P10144] synonym: "CTLA-1" EXACT [UniProtKB:P10144] synonym: "CTSGL1" EXACT [UniProtKB:P10144] synonym: "Cytotoxic T-lymphocyte proteinase 2" EXACT [UniProtKB:P10144] synonym: "EC 3.4.21.79" EXACT [UniProtKB:P10144] synonym: "Fragmentin-2" EXACT [UniProtKB:P10144] synonym: "Granzyme-2" EXACT [UniProtKB:P10144] synonym: "HLP" EXACT [UniProtKB:P10144] synonym: "Human lymphocyte protein" EXACT [UniProtKB:P10144] synonym: "Lymphocyte protease" EXACT [UniProtKB:P10144] synonym: "SECT" EXACT [UniProtKB:P10144] synonym: "T-cell serine protease 1-3E" EXACT [UniProtKB:P10144] xref: EMBL:AAA36603.1 xref: EMBL:AAA36627.1 xref: EMBL:AAA52118.1 xref: EMBL:AAA67124.1 xref: EMBL:AAA75490.1 xref: EMBL:AAB59528.1 xref: EMBL:AAH30195.1 xref: UniProtKB:P10144 xref: UniProtKB:Q8N1D2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018049 ! GZMB_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000708 ! granzyme B activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000186 ! immunological synapse relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000675 ! cleavage of lamin [Term] id: CCO:B0054972 name: CCL3_HUMAN def: "C-C motif chemokine 3 precursor" [UniProtKB:P10147] synonym: "G0/G1 switch regulatory protein 19-1" EXACT [UniProtKB:P10147] synonym: "G0S19-1 protein" EXACT [UniProtKB:P10147] synonym: "Macrophage inflammatory protein 1-alpha" EXACT [UniProtKB:P10147] synonym: "MIP-1-alpha" EXACT [UniProtKB:P10147] synonym: "PAT 464.1" EXACT [UniProtKB:P10147] synonym: "SIS-beta" EXACT [UniProtKB:P10147] synonym: "Small-inducible cytokine A3" EXACT [UniProtKB:P10147] synonym: "Tonsillar lymphocyte LD78 alpha protein" EXACT [UniProtKB:P10147] xref: EMBL:AAA35858.1 xref: EMBL:AAA36316.1 xref: EMBL:AAA57255.1 xref: EMBL:AAC03539.1 xref: EMBL:AAH71834.1 xref: EMBL:BAA00029.1 xref: EMBL:BAA14172.1 xref: EMBL:CAA27388.1 xref: EMBL:CAA27643.1 xref: UniProtKB:P10147 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017272 ! CCL3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0005617 ! chemoattractant activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0054973 name: POK10_HUMAN def: "HERV-K_5q33.3 provirus ancestral Pol protein" [UniProtKB:P10266] synonym: "HERV-K10 Pol protein" EXACT [UniProtKB:P10266] synonym: "HERV-K107 Pol protein" EXACT [UniProtKB:P10266] xref: EMBL:AAA88033.1 xref: EMBL:AAD51796.1 xref: EMBL:CAA71417.1 xref: UniProtKB:P10266 xref: UniProtKB:P87890 xref: UniProtKB:Q14273 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0054974 name: ARRS_HUMAN def: "S-arrestin" [UniProtKB:P10523] synonym: "48 kDa protein" EXACT [UniProtKB:P10523] synonym: "Retinal S-antigen" EXACT [UniProtKB:P10523] synonym: "Rod photoreceptor arrestin" EXACT [UniProtKB:P10523] synonym: "S-AG" EXACT [UniProtKB:P10523] xref: EMBL:AAC50992.1 xref: EMBL:AAY14861.1 xref: EMBL:CAA30984.1 xref: UniProtKB:P10523 xref: UniProtKB:Q53SV3 xref: UniProtKB:Q99858 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017052 ! SAG_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001112 ! rhodopsin mediated signaling pathway [Term] id: CCO:B0054975 name: PTPRF_HUMAN def: "Receptor-type tyrosine-protein phosphatase F precursor" [UniProtKB:P10586] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P10586] synonym: "LAR protein" EXACT [UniProtKB:P10586] synonym: "Leukocyte antigen related" EXACT [UniProtKB:P10586] xref: EMBL:CAA68754.1 xref: UniProtKB:P10586 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019550 ! PTPRF_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000725 ! transmembrane receptor protein tyrosine phosphatase signaling pathway [Term] id: CCO:B0054976 name: TAU_HUMAN def: "Microtubule-associated protein tau" [UniProtKB:P10636] synonym: "Neurofibrillary tangle protein" EXACT [UniProtKB:P10636] synonym: "Paired helical filament-tau" EXACT [UniProtKB:P10636] synonym: "PHF-tau" EXACT [UniProtKB:P10636] xref: EMBL:AAA57264.1 xref: EMBL:AAA60615.1 xref: EMBL:AAC04277.1 xref: EMBL:AAC04278.1 xref: EMBL:AAC04279.1 xref: EMBL:AAH00558.1 xref: EMBL:AAH98281.1 xref: EMBL:AAH99721.1 xref: EMBL:AAI01937.1 xref: EMBL:AAI14505.1 xref: EMBL:AAI14949.1 xref: EMBL:AAP35418.1 xref: EMBL:AAS17881.1 xref: EMBL:AAU45390.1 xref: EMBL:CAA32636.1 xref: EMBL:CAG26750.1 xref: UniProtKB:P10636 xref: UniProtKB:P18518 xref: UniProtKB:Q14799 xref: UniProtKB:Q15549 xref: UniProtKB:Q15550 xref: UniProtKB:Q15551 xref: UniProtKB:Q1RMF6 xref: UniProtKB:Q53YB1 xref: UniProtKB:Q5CZI7 xref: UniProtKB:Q5XWF0 xref: UniProtKB:Q6QT54 xref: UniProtKB:Q9UDJ3 xref: UniProtKB:Q9UMH0 xref: UniProtKB:Q9UQ96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020151 ! MAPT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0001383 ! regulation of microtubule polymerization relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization relationship: participates_in CCO:P0002548 ! positive regulation of axon extension relationship: transforms_into CCO:B0071132 ! TAU_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0071133 ! TAU_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0071134 ! TAU_HUMAN-Phosphothreonine50 relationship: transforms_into CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: transforms_into CCO:B0071136 ! TAU_HUMAN-Phosphothreonine470 relationship: transforms_into CCO:B0071137 ! TAU_HUMAN-asparagine484 relationship: transforms_into CCO:B0071138 ! TAU_HUMAN-Phosphothreonine492 relationship: transforms_into CCO:B0071139 ! TAU_HUMAN-Phosphothreonine498 relationship: transforms_into CCO:B0071140 ! TAU_HUMAN-Phosphotyrosine514 relationship: transforms_into CCO:B0071141 ! TAU_HUMAN-Phosphoserine515 relationship: transforms_into CCO:B0071142 ! TAU_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0071143 ! TAU_HUMAN-Phosphoserine519 relationship: transforms_into CCO:B0071144 ! TAU_HUMAN-Phosphothreonine522 relationship: transforms_into CCO:B0071145 ! TAU_HUMAN-Phosphothreonine529 relationship: transforms_into CCO:B0071146 ! TAU_HUMAN-Phosphoserine531 relationship: transforms_into CCO:B0071147 ! TAU_HUMAN-Phosphothreonine534 relationship: transforms_into CCO:B0071148 ! TAU_HUMAN-Phosphothreonine548 relationship: transforms_into CCO:B0071149 ! TAU_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0071150 ! TAU_HUMAN-Phosphoserine554 relationship: transforms_into CCO:B0071151 ! TAU_HUMAN-Phosphoserine579 relationship: transforms_into CCO:B0071152 ! TAU_HUMAN-asparagine596 relationship: transforms_into CCO:B0071153 ! TAU_HUMAN-Phosphoserine610 relationship: transforms_into CCO:B0071154 ! TAU_HUMAN-Phosphoserine622 relationship: transforms_into CCO:B0071155 ! TAU_HUMAN-Phosphoserine641 relationship: transforms_into CCO:B0071156 ! TAU_HUMAN-Phosphoserine673 relationship: transforms_into CCO:B0071157 ! TAU_HUMAN-Phosphoserine713 relationship: transforms_into CCO:B0071158 ! TAU_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0071159 ! TAU_HUMAN-Phosphothreonine720 relationship: transforms_into CCO:B0071160 ! TAU_HUMAN-Phosphoserine721 relationship: transforms_into CCO:B0071161 ! TAU_HUMAN-Phosphoserine726 relationship: transforms_into CCO:B0071162 ! TAU_HUMAN-Phosphoserine729 relationship: transforms_into CCO:B0071163 ! TAU_HUMAN-Phosphothreonine731 relationship: transforms_into CCO:B0071164 ! TAU_HUMAN-Phosphoserine733 relationship: transforms_into CCO:B0071165 ! TAU_HUMAN-Phosphoserine739 relationship: transforms_into CCO:B0071166 ! TAU_HUMAN-Phosphothreonine744 [Term] id: CCO:B0054977 name: KIT_HUMAN def: "Mast/stem cell growth factor receptor precursor" [UniProtKB:P10721] synonym: "c-kit" EXACT [UniProtKB:P10721] synonym: "CD117 antigen" EXACT [UniProtKB:P10721] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P10721] synonym: "Proto-oncogene tyrosine-protein kinase Kit" EXACT [UniProtKB:P10721] synonym: "SCFR" EXACT [UniProtKB:P10721] xref: EMBL:AAB29529.1 xref: EMBL:AAC50968.1 xref: EMBL:CAA29548.1 xref: EMBL:CAA49159.1 xref: UniProtKB:P10721 xref: UniProtKB:Q9UM99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018406 ! KIT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002917 ! epithelial cell proliferation relationship: transforms_into CCO:B0067364 ! KIT_HUMAN-Phosphotyrosine568 relationship: transforms_into CCO:B0067365 ! KIT_HUMAN-Phosphotyrosine570 relationship: transforms_into CCO:B0067366 ! KIT_HUMAN-Phosphotyrosine703 relationship: transforms_into CCO:B0067367 ! KIT_HUMAN-Phosphotyrosine823 relationship: transforms_into CCO:B0067368 ! KIT_HUMAN-Phosphotyrosine936 [Term] id: CCO:B0054978 name: THA_HUMAN def: "Thyroid hormone receptor alpha" [UniProtKB:P10827] synonym: "c-erbA-1" EXACT [UniProtKB:P10827] synonym: "C-erbA-alpha" EXACT [UniProtKB:P10827] synonym: "EAR-7" EXACT [UniProtKB:P10827] synonym: "EAR7" EXACT [UniProtKB:P10827] synonym: "Nuclear receptor subfamily 1 group A member 1" EXACT [UniProtKB:P10827] xref: EMBL:AAA35783.1 xref: EMBL:AAA52333.1 xref: EMBL:AAA61176.1 xref: EMBL:AAA66021.1 xref: EMBL:AAH00261.1 xref: EMBL:AAH02728.1 xref: EMBL:AAH35137.1 xref: EMBL:AAM77692.1 xref: EMBL:CAA38749.1 xref: EMBL:CAA38899.1 xref: EMBL:CAA68539.1 xref: EMBL:CAB57886.1 xref: UniProtKB:P10827 xref: UniProtKB:P21205 xref: UniProtKB:Q8N6A1 xref: UniProtKB:Q96H73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020252 ! THRA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017849 ! tr-crsp6-1 physical interaction relationship: participates_in CCO:I0018414 ! ncoa6-thra-1 physical interaction relationship: participates_in CCO:I0018419 ! ncoa6-thra-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054979 name: THB_HUMAN def: "Thyroid hormone receptor beta" [UniProtKB:P10828] synonym: "Nuclear receptor subfamily 1 group A member 2" EXACT [UniProtKB:P10828] xref: EMBL:AAA35677.1 xref: EMBL:AAI06930.1 xref: EMBL:AAI06931.1 xref: EMBL:AAQ23704.1 xref: EMBL:AAQ23705.1 xref: EMBL:AAQ23706.1 xref: EMBL:AAQ23707.1 xref: EMBL:AAQ23708.1 xref: EMBL:AAQ23709.1 xref: EMBL:AAQ23710.1 xref: EMBL:CAA28412.1 xref: EMBL:CAA52606.1 xref: UniProtKB:P10828 xref: UniProtKB:P37243 xref: UniProtKB:Q13986 xref: UniProtKB:Q3KP35 xref: UniProtKB:Q6WGL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020253 ! THRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017651 ! hrmt1l1-thrb-1 physical interaction relationship: participates_in CCO:I0018415 ! ncoa6-thrb-1 physical interaction relationship: participates_in CCO:I0018420 ! ncoa6-thrb-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0054980 name: CLUS_HUMAN def: "Clusterin precursor" [UniProtKB:P10909] synonym: "Apo-J" EXACT [UniProtKB:P10909] synonym: "Apolipoprotein J" EXACT [UniProtKB:P10909] synonym: "CLI" EXACT [UniProtKB:P10909] synonym: "Complement cytolysis inhibitor" EXACT [UniProtKB:P10909] synonym: "Complement-associated protein SP-40,40" EXACT [UniProtKB:P10909] synonym: "Ku70-binding protein 1" EXACT [UniProtKB:P10909] synonym: "NA1/NA2" EXACT [UniProtKB:P10909] synonym: "Testosterone-repressed prostate message 2" EXACT [UniProtKB:P10909] synonym: "TRPM-2" EXACT [UniProtKB:P10909] xref: EMBL:AAA35692.1 xref: EMBL:AAA51765.1 xref: EMBL:AAA60321.1 xref: EMBL:AAA60567.1 xref: EMBL:AAB06507.1 xref: EMBL:AAB06508.1 xref: EMBL:AAH10514.1 xref: EMBL:AAH19588.1 xref: EMBL:AAP88927.1 xref: EMBL:CAA32847.1 xref: EMBL:CAI45990.1 xref: UniProtKB:P10909 xref: UniProtKB:P11380 xref: UniProtKB:P11381 xref: UniProtKB:Q5HYC1 xref: UniProtKB:Q7Z5B9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017393 ! CLU_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000776 ! aggresome relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002411 ! positive regulation of cell differentiation [Term] id: CCO:B0054981 name: MCF2_HUMAN def: "Proto-oncogene DBL" [UniProtKB:P10911] synonym: "Proto-oncogene MCF-2" EXACT [UniProtKB:P10911] xref: EMBL:AAA52172.1 xref: EMBL:BAC41200.1 xref: EMBL:BAC41201.1 xref: EMBL:CAA21955.1 xref: EMBL:CAA31069.1 xref: EMBL:CAA31617.1 xref: EMBL:CAB55301.1 xref: UniProtKB:P10911 xref: UniProtKB:P14919 xref: UniProtKB:Q5JYJ4 xref: UniProtKB:Q8IUF3 xref: UniProtKB:Q8IUF4 xref: UniProtKB:Q9UJB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018586 ! MCF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0068055 ! MCF2_HUMAN-Phosphoserine742 [Term] id: CCO:B0054982 name: MLRV_HUMAN def: "Myosin regulatory light chain 2, ventricular/cardiac muscle isoform" [UniProtKB:P10916] synonym: "MLC-2" EXACT [UniProtKB:P10916] synonym: "MLC-2v" EXACT [UniProtKB:P10916] xref: EMBL:AAA91832.1 xref: EMBL:AAB29658.2 xref: EMBL:AAB91993.1 xref: EMBL:AAH15821.1 xref: EMBL:AAH31006.1 xref: EMBL:AAH31008.1 xref: EMBL:CAA32510.1 xref: UniProtKB:P10916 xref: UniProtKB:Q16123 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018636 ! MYL2_human relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000324 ! actin monomer binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_function CCO:F0004935 ! myosin heavy chain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0000932 ! myofibril relationship: located_in CCO:C0000933 ! sarcomere relationship: participates_in CCO:I0020585 ! lrsam1-myl2 physical interaction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: transforms_into CCO:B0068235 ! MLRV_HUMAN-N,N,N-trimethylalanine2 [Term] id: CCO:B0054983 name: CD8B_HUMAN def: "T-cell surface glycoprotein CD8 beta chain precursor" [UniProtKB:P10966] synonym: "CD8b antigen" EXACT [UniProtKB:P10966] xref: EMBL:AAA35664.1 xref: EMBL:AAB21669.2 xref: EMBL:AAB21670.2 xref: EMBL:AAB21671.2 xref: EMBL:AAB21672.2 xref: EMBL:AAD13877.1 xref: EMBL:CAA31795.1 xref: EMBL:CAA31796.1 xref: EMBL:CAA31797.1 xref: EMBL:CAA31803.1 xref: EMBL:CAA68750.1 xref: UniProtKB:P10966 xref: UniProtKB:P14860 xref: UniProtKB:P14861 xref: UniProtKB:Q15980 xref: UniProtKB:Q9UQ55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017315 ! CD8B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0005648 ! MHC class I protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0064175 ! CD8B_HUMAN-Phosphotyrosine209 [Term] id: CCO:B0054984 name: IAPP_HUMAN def: "Islet amyloid polypeptide precursor" [UniProtKB:P10997] synonym: "Amylin" EXACT [UniProtKB:P10997] synonym: "DAP" EXACT [UniProtKB:P10997] synonym: "Diabetes-associated peptide" EXACT [UniProtKB:P10997] synonym: "Insulinoma amyloid peptide" EXACT [UniProtKB:P10997] xref: EMBL:AAA35524.1 xref: EMBL:AAA35983.1 xref: EMBL:AAA51728.1 xref: EMBL:AAA52281.1 xref: EMBL:CAA33031.1 xref: EMBL:CAA33032.1 xref: EMBL:CAA33033.1 xref: EMBL:CAA37002.1 xref: EMBL:CAA39504.1 xref: EMBL:CAA48724.1 xref: EMBL:CAB57803.1 xref: EMBL:CAB57804.1 xref: UniProtKB:P10997 xref: UniProtKB:Q14598 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018206 ! IAPP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: transforms_into CCO:B0066979 ! IAPP_HUMAN-Tyrosine amide70 [Term] id: CCO:B0054985 name: LAMC1_HUMAN def: "Laminin subunit gamma-1 precursor" [UniProtKB:P11047] synonym: "Laminin B2 chain" EXACT [UniProtKB:P11047] xref: EMBL:AAA59488.1 xref: EMBL:AAA59489.1 xref: EMBL:AAA59492.1 xref: EMBL:CAA32122.1 xref: UniProtKB:P11047 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018454 ! LAMC1_human relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000228 ! basal lamina relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: located_in CCO:C0001759 ! laminin-10 complex relationship: participates_in CCO:I0020456 ! snapap-lamc1 physical interaction relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0054986 name: ACM1_HUMAN def: "Muscarinic acetylcholine receptor M1" [UniProtKB:P11229] xref: EMBL:AAH07740.1 xref: EMBL:AAH22984.1 xref: EMBL:AAM18938.1 xref: EMBL:CAA33334.1 xref: EMBL:CAA36291.1 xref: EMBL:CAA68560.1 xref: UniProtKB:P11229 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016898 ! CHRM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000742 ! muscarinic acetylcholine receptor, phospholipase C activating pathway relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: transforms_into CCO:B0065375 ! ACM1_HUMAN-Phosphoserine451 relationship: transforms_into CCO:B0065376 ! ACM1_HUMAN-Phosphothreonine455 relationship: transforms_into CCO:B0065377 ! ACM1_HUMAN-Phosphoserine457 [Term] id: CCO:B0054987 name: ACHB_HUMAN def: "Acetylcholine receptor subunit beta precursor" [UniProtKB:P11230] xref: EMBL:AAH11371.1 xref: EMBL:CAA32939.1 xref: UniProtKB:P11230 xref: UniProtKB:Q96FB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013732 ! CHRNB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002725 ! channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0005634 ! acetylcholine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0020531 ! chrnb1-cops6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065318 ! ACHB_HUMAN-Phosphotyrosine390 [Term] id: CCO:B0054988 name: RALA_HUMAN def: "Ras-related protein Ral-A precursor" [UniProtKB:P11233] xref: EMBL:AAA36542.1 xref: EMBL:AAH39858.1 xref: EMBL:AAM12624.1 xref: EMBL:CAA33118.1 xref: UniProtKB:P11233 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019618 ! RALA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0069724 ! RALA_HUMAN-Cysteine methyl ester203 [Term] id: CCO:B0054989 name: RALB_HUMAN def: "Ras-related protein Ral-B precursor" [UniProtKB:P11234] xref: EMBL:AAA60250.1 xref: EMBL:AAH18163.1 xref: EMBL:AAM12625.1 xref: EMBL:AAP35599.1 xref: EMBL:CAA33119.1 xref: UniProtKB:P11234 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019619 ! RALB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015824 ! ralb-ralbp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0069725 ! RALB_HUMAN-Cysteine methyl ester203 [Term] id: CCO:B0054990 name: SPTB1_HUMAN def: "Spectrin beta chain, erythrocyte" [UniProtKB:P11277] synonym: "Beta-I spectrin" EXACT [UniProtKB:P11277] xref: EMBL:AAA60571.1 xref: EMBL:AAA60572.1 xref: EMBL:AAA60578.1 xref: EMBL:AAA60579.1 xref: EMBL:AAA63259.1 xref: EMBL:CAA42097.1 xref: EMBL:CAA42098.1 xref: UniProtKB:P11277 xref: UniProtKB:Q15510 xref: UniProtKB:Q15519 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020024 ! SPTB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019199 ! spta1-sptb1-1 direct interaction relationship: participates_in CCO:I0019200 ! spta2-sptb1-2 direct interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0070824 ! SPTB1_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0070825 ! SPTB1_HUMAN-Phosphothreonine2110 relationship: transforms_into CCO:B0070826 ! SPTB1_HUMAN-Phosphoserine2114 relationship: transforms_into CCO:B0070827 ! SPTB1_HUMAN-Phosphoserine2117 relationship: transforms_into CCO:B0070828 ! SPTB1_HUMAN-Phosphoserine2123 relationship: transforms_into CCO:B0070829 ! SPTB1_HUMAN-Phosphoserine2125 relationship: transforms_into CCO:B0070830 ! SPTB1_HUMAN-Phosphoserine2128 [Term] id: CCO:B0054991 name: ERG_HUMAN def: "Transcriptional regulator ERG" [UniProtKB:P11308] synonym: "Transforming protein ERG" EXACT [UniProtKB:P11308] xref: EMBL:AAA35811.1 xref: EMBL:AAA52398.1 xref: EMBL:AAB29724.1 xref: EMBL:AAH40168.1 xref: EMBL:AAP41719.1 xref: EMBL:AAP41720.1 xref: UniProtKB:P11308 xref: UniProtKB:Q16113 xref: UniProtKB:Q6XXX4 xref: UniProtKB:Q6XXX5 xref: UniProtKB:Q8IXK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017727 ! ERG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018856 ! erg-setdb1-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0065134 ! ERG_HUMAN-Phosphoserine93 [Term] id: CCO:B0054992 name: VDR_HUMAN def: "Vitamin D3 receptor" [UniProtKB:P11473] synonym: "1,25-dihydroxyvitamin D3 receptor" EXACT [UniProtKB:P11473] synonym: "Nuclear receptor subfamily 1 group I member 1" EXACT [UniProtKB:P11473] synonym: "VDR" EXACT [UniProtKB:P11473] xref: EMBL:AAA61273.1 xref: EMBL:AAA61274.1 xref: EMBL:AAB95155.1 xref: EMBL:AAH60832.1 xref: EMBL:AAP88938.1 xref: EMBL:BAA83389.1 xref: EMBL:CAA47824.1 xref: UniProtKB:P11473 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020440 ! VDR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001900 ! vitamin D3 receptor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018418 ! ncoa6-vdr-1 physical interaction relationship: participates_in CCO:I0018424 ! ncoa6-vdr-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0054993 name: UTER_HUMAN def: "Uteroglobin precursor" [UniProtKB:P11684] synonym: "CC10" EXACT [UniProtKB:P11684] synonym: "CCPBP" EXACT [UniProtKB:P11684] synonym: "Clara cell phospholipid-binding protein" EXACT [UniProtKB:P11684] synonym: "Clara cells 10 kDa secretory protein" EXACT [UniProtKB:P11684] synonym: "Secretoglobin family 1A member 1" EXACT [UniProtKB:P11684] synonym: "UP1" EXACT [UniProtKB:P11684] synonym: "Urinary protein 1" EXACT [UniProtKB:P11684] synonym: "Urine protein 1" EXACT [UniProtKB:P11684] xref: EMBL:AAA18297.1 xref: EMBL:AAA81885.1 xref: EMBL:AAH04481.1 xref: EMBL:CAA31584.1 xref: EMBL:CAA42532.1 xref: EMBL:CAG46579.1 xref: UniProtKB:P11684 xref: UniProtKB:Q6FHH3 xref: UniProtKB:Q9UCM2 xref: UniProtKB:Q9UCM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020424 ! SCGB1A1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0004187 ! phospholipase A2 inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054994 name: MPRI_HUMAN def: "Cation-independent mannose-6-phosphate receptor precursor" [UniProtKB:P11717] synonym: "300 kDa mannose 6-phosphate receptor" EXACT [UniProtKB:P11717] synonym: "CD222 antigen" EXACT [UniProtKB:P11717] synonym: "CI Man-6-P receptor" EXACT [UniProtKB:P11717] synonym: "CI-MPR" EXACT [UniProtKB:P11717] synonym: "IGF-II receptor" EXACT [UniProtKB:P11717] synonym: "Insulin-like growth factor 2 receptor" EXACT [UniProtKB:P11717] synonym: "Insulin-like growth factor II receptor" EXACT [UniProtKB:P11717] synonym: "M6P/IGF2 receptor" EXACT [UniProtKB:P11717] synonym: "M6P/IGF2R" EXACT [UniProtKB:P11717] synonym: "M6PR" EXACT [UniProtKB:P11717] synonym: "MPR 300" EXACT [UniProtKB:P11717] xref: EMBL:AAA59866.1 xref: EMBL:AAF16870.1 xref: EMBL:AAL04402.1 xref: EMBL:AAP37954.1 xref: EMBL:CAA68395.1 xref: EMBL:CAH72014.1 xref: EMBL:CAI19940.1 xref: UniProtKB:P11717 xref: UniProtKB:Q7Z7G9 xref: UniProtKB:Q96PT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018649 ! IGF2R_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001347 ! insulin-like growth factor receptor activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000258 ! nuclear envelope lumen relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068263 ! MPRI_HUMAN-Phosphoserine2409 relationship: transforms_into CCO:B0068264 ! MPRI_HUMAN-Phosphoserine2479 relationship: transforms_into CCO:B0068265 ! MPRI_HUMAN-Phosphoserine2484 [Term] id: CCO:B0054995 name: CD20_HUMAN def: "B-lymphocyte antigen CD20" [UniProtKB:P11836] synonym: "B-lymphocyte surface antigen B1" EXACT [UniProtKB:P11836] synonym: "Bp35" EXACT [UniProtKB:P11836] synonym: "CD20 antigen" EXACT [UniProtKB:P11836] synonym: "Leu-16" EXACT [UniProtKB:P11836] synonym: "Membrane-spanning 4-domains subfamily A member 1" EXACT [UniProtKB:P11836] xref: EMBL:AAA35581.1 xref: EMBL:AAA88911.1 xref: EMBL:AAH02807.1 xref: EMBL:CAA30179.1 xref: EMBL:CAA30180.1 xref: EMBL:CAA31046.1 xref: EMBL:EAW73889.1 xref: UniProtKB:A6NMS4 xref: UniProtKB:P08984 xref: UniProtKB:P11836 xref: UniProtKB:Q13963 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017289 ! MS4A1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0054996 name: CD79A_HUMAN def: "B-cell antigen receptor complex-associated protein alpha-chain precursor" [UniProtKB:P11912] synonym: "CD79a antigen" EXACT [UniProtKB:P11912] synonym: "Ig-alpha" EXACT [UniProtKB:P11912] synonym: "MB-1 membrane glycoprotein" EXACT [UniProtKB:P11912] synonym: "Membrane-bound immunoglobulin-associated protein" EXACT [UniProtKB:P11912] synonym: "Surface IgM-associated protein" EXACT [UniProtKB:P11912] xref: EMBL:AAA20495.1 xref: EMBL:AAA59556.1 xref: EMBL:AAA59557.1 xref: EMBL:AAA60270.1 xref: EMBL:AAB20812.1 xref: EMBL:AAB23558.1 xref: EMBL:BAD97091.1 xref: EMBL:CAA31802.1 xref: EMBL:CAA58523.1 xref: UniProtKB:P11912 xref: UniProtKB:Q53FB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017308 ! CD79A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002040 ! B cell proliferation relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway relationship: transforms_into CCO:B0064173 ! CD79A_HUMAN-Phosphotyrosine188 relationship: transforms_into CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 [Term] id: CCO:B0054997 name: DCOR_HUMAN def: "Ornithine decarboxylase" [UniProtKB:P11926] synonym: "EC 4.1.1.17" EXACT [UniProtKB:P11926] synonym: "ODC" EXACT [UniProtKB:P11926] xref: EMBL:AAA59966.2 xref: EMBL:AAA59967.1 xref: EMBL:AAA59968.1 xref: EMBL:AAA59969.1 xref: EMBL:AAA60563.1 xref: EMBL:AAA60564.1 xref: EMBL:AAH25296.1 xref: EMBL:AAV88093.1 xref: EMBL:CAA34353.1 xref: EMBL:CAA37369.1 xref: EMBL:CAA39047.1 xref: UniProtKB:P11926 xref: UniProtKB:Q6LDS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017535 ! ODC1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000968 ! ornithine decarboxylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003398 ! carboxy-lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0064659 ! DCOR_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0064660 ! DCOR_HUMAN-S-nitrosocysteine360 [Term] id: CCO:B0054998 name: IMDH2_HUMAN def: "Inosine-5'-monophosphate dehydrogenase 2" [UniProtKB:P12268] synonym: "EC 1.1.1.205" EXACT [UniProtKB:P12268] synonym: "IMP dehydrogenase 2" EXACT [UniProtKB:P12268] synonym: "IMPD 2" EXACT [UniProtKB:P12268] synonym: "IMPDH-II" EXACT [UniProtKB:P12268] xref: EMBL:AAA36112.1 xref: EMBL:AAA36113.1 xref: EMBL:AAA67054.1 xref: EMBL:AAB70699.1 xref: EMBL:AAH06124.1 xref: EMBL:AAH12840.1 xref: EMBL:AAH15567.1 xref: UniProtKB:P12268 xref: UniProtKB:Q6LEF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018277 ! IMPDH2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000432 ! IMP dehydrogenase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016084 ! impdh2-pias4 physical interaction relationship: participates_in CCO:I0018901 ! ubqln4-impdh2 physical interaction relationship: participates_in CCO:P0002724 ! lymphocyte proliferation relationship: transforms_into CCO:B0067088 ! IMDH2_HUMAN-Phosphotyrosine400 [Term] id: CCO:B0054999 name: PTHR_HUMAN def: "Parathyroid hormone-related protein precursor" [UniProtKB:P12272] synonym: "PTH-rP" EXACT [UniProtKB:P12272] synonym: "PTHrP" EXACT [UniProtKB:P12272] xref: EMBL:AAA60216.1 xref: EMBL:AAA60217.1 xref: EMBL:AAA60218.1 xref: EMBL:AAA60221.1 xref: EMBL:AAA60358.1 xref: EMBL:AAA60359.1 xref: EMBL:AAA60360.1 xref: EMBL:AAH05961.1 xref: EMBL:CAA32480.1 xref: UniProtKB:P12272 xref: UniProtKB:Q15251 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019543 ! PTHLH_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055000 name: MYCL1_HUMAN def: "L-myc-1 proto-oncogene protein" [UniProtKB:P12524] xref: EMBL:AAA59878.1 xref: EMBL:AAA59879.1 xref: EMBL:AAH11864.1 xref: EMBL:CAA30248.1 xref: EMBL:CAA30249.1 xref: EMBL:CAI19407.1 xref: EMBL:CAI19408.1 xref: UniProtKB:P12524 xref: UniProtKB:Q14897 xref: UniProtKB:Q5QPL0 xref: UniProtKB:Q5QPL1 xref: UniProtKB:Q9NUE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018691 ! MYCL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068360 ! MYCL1_HUMAN-Phosphothreonine310 relationship: transforms_into CCO:B0068361 ! MYCL1_HUMAN-Phosphoserine313 [Term] id: CCO:B0055001 name: MYCL2_HUMAN def: "L-myc-2 protein" [UniProtKB:P12525] xref: EMBL:AAA59883.1 xref: UniProtKB:P12525 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018692 ! MYCL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068362 ! MYCL2_HUMAN-Phosphoserine306 [Term] id: CCO:B0055002 name: GRAA_HUMAN def: "Granzyme A precursor" [UniProtKB:P12544] synonym: "CTL tryptase" EXACT [UniProtKB:P12544] synonym: "Cytotoxic T-lymphocyte proteinase 1" EXACT [UniProtKB:P12544] synonym: "EC 3.4.21.78" EXACT [UniProtKB:P12544] synonym: "Fragmentin-1" EXACT [UniProtKB:P12544] synonym: "Granzyme-1" EXACT [UniProtKB:P12544] synonym: "H factor" EXACT [UniProtKB:P12544] synonym: "Hanukkah factor" EXACT [UniProtKB:P12544] synonym: "HF" EXACT [UniProtKB:P12544] xref: EMBL:AAA52647.1 xref: EMBL:AAD00009.1 xref: EMBL:AAH15739.1 xref: EMBL:CAG33249.1 xref: UniProtKB:P12544 xref: UniProtKB:Q6IB36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018048 ! GZMA_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000707 ! granzyme A activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000186 ! immunological synapse relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018178 ! gzma-gzma-1 covalent binding relationship: participates_in CCO:P0000675 ! cleavage of lamin [Term] id: CCO:B0055003 name: ODBA_HUMAN def: "2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor" [UniProtKB:P12694] synonym: "BCKDE1A" EXACT [UniProtKB:P12694] synonym: "BCKDH E1-alpha" EXACT [UniProtKB:P12694] synonym: "Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain" EXACT [UniProtKB:P12694] synonym: "EC 1.2.4.4" EXACT [UniProtKB:P12694] xref: EMBL:AAA35590.1 xref: EMBL:AAB19268.2 xref: EMBL:AAB20222.2 xref: EMBL:AAB59549.1 xref: EMBL:AAH07878.1 xref: EMBL:AAH08933.1 xref: EMBL:AAH23983.1 xref: EMBL:CAA78475.1 xref: UniProtKB:P12694 xref: UniProtKB:Q16034 xref: UniProtKB:Q16472 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019039 ! BCKDHA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017814 ! bckdha-bckdhb-1 direct interaction relationship: participates_in CCO:I0018119 ! bckdha-bckdhb-5 direct interaction relationship: participates_in CCO:I0018120 ! bckdha-bckdhb-6 direct interaction relationship: participates_in CCO:I0018121 ! bckdha-bckdhb-7 direct interaction relationship: participates_in CCO:I0018122 ! bckdha-bckdhb-8 direct interaction relationship: participates_in CCO:I0018252 ! bckdha-bckdhb-2 direct interaction relationship: participates_in CCO:I0018253 ! bckdha-bckdhb-3 direct interaction relationship: participates_in CCO:I0018254 ! bckdha-bckdhb-4 direct interaction relationship: participates_in CCO:I0018711 ! bckdha-bckdhb-9 direct interaction relationship: participates_in CCO:I0018712 ! bckdha-bckdhb-10 direct interaction relationship: participates_in CCO:I0018713 ! bckdha-bckdhb-11 direct interaction relationship: participates_in CCO:I0018714 ! bckdha-bckdhb-12 direct interaction relationship: participates_in CCO:I0018715 ! bckdha-bckdhb-13 direct interaction relationship: participates_in CCO:I0018716 ! bckdha-bckdhb-14 direct interaction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068953 ! ODBA_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0068954 ! ODBA_HUMAN-Phosphotyrosine345 relationship: transforms_into CCO:B0068955 ! ODBA_HUMAN-Phosphoserine347 [Term] id: CCO:B0055004 name: SKI_HUMAN def: "Ski oncogene" [UniProtKB:P12755] synonym: "C-ski" EXACT [UniProtKB:P12755] xref: EMBL:CAA33288.1 xref: EMBL:CAI12482.1 xref: UniProtKB:P12755 xref: UniProtKB:Q5SYT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019929 ! SKI_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0008978 ! ski-madh3-1 physical interaction relationship: participates_in CCO:I0017977 ! ski-madh4-1 physical interaction relationship: participates_in CCO:I0017978 ! ski-ncor1-1 physical interaction relationship: participates_in CCO:I0017979 ! ski-sin3a-1 physical interaction relationship: participates_in CCO:I0018583 ! madh4-ski-1 physical interaction relationship: participates_in CCO:I0018750 ! ski-smad4-1 direct interaction relationship: participates_in CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:B0055005 name: SKIL_HUMAN def: "Ski-like protein" [UniProtKB:P12757] synonym: "Ski-related oncogene" EXACT [UniProtKB:P12757] synonym: "Ski-related protein" EXACT [UniProtKB:P12757] xref: EMBL:AAB65850.1 xref: EMBL:AAH59386.1 xref: EMBL:CAA33287.1 xref: EMBL:CAA33289.1 xref: EMBL:CAA79636.1 xref: UniProtKB:A6NGT1 xref: UniProtKB:O00464 xref: UniProtKB:P12756 xref: UniProtKB:P12757 xref: UniProtKB:Q07501 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019928 ! SKIL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001382 ! transforming growth factor beta receptor, cytoplasmic mediator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055006 name: ACE_HUMAN def: "Angiotensin-converting enzyme precursor" [UniProtKB:P12821] synonym: "CD143 antigen" EXACT [UniProtKB:P12821] synonym: "Dipeptidyl carboxypeptidase I" EXACT [UniProtKB:P12821] synonym: "EC 3.2.1.-" EXACT [UniProtKB:P12821] synonym: "EC 3.4.15.1" EXACT [UniProtKB:P12821] synonym: "Kininase II" EXACT [UniProtKB:P12821] xref: EMBL:AAA51684.1 xref: EMBL:AAA60611.1 xref: EMBL:AAD28560.1 xref: EMBL:AAR03504.1 xref: EMBL:BAD92208.1 xref: EMBL:CAA34362.1 xref: UniProtKB:P12821 xref: UniProtKB:P22966 xref: UniProtKB:Q53YX9 xref: UniProtKB:Q59GY8 xref: UniProtKB:Q7M4L4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016885 ! ACE_human relationship: has_function CCO:F0000649 ! carboxypeptidase activity relationship: has_function CCO:F0000692 ! peptidyl-dipeptidase A activity relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_function CCO:F0004724 ! bradykinin receptor binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001107 ! regulation of smooth muscle cell migration relationship: participates_in CCO:P0001724 ! mononuclear cell proliferation relationship: transforms_into CCO:B0065315 ! ACE_HUMAN-Phosphothreonine716 relationship: transforms_into CCO:B0065316 ! ACE_HUMAN-Phosphoserine1299 [Term] id: CCO:B0055007 name: MOTI_HUMAN def: "Promotilin precursor" [UniProtKB:P12872] xref: EMBL:AAA59860.1 xref: EMBL:AAH69675.1 xref: EMBL:CAA33448.1 xref: EMBL:CAA68690.1 xref: UniProtKB:P12872 xref: UniProtKB:Q6NSY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018645 ! MLN_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055008 name: LYL1_HUMAN def: "Protein lyl-1" [UniProtKB:P12980] synonym: "Lymphoblastic leukemia-derived sequence 1" EXACT [UniProtKB:P12980] xref: EMBL:AAA88084.1 xref: EMBL:AAA88085.1 xref: EMBL:AAA92488.1 xref: EMBL:AAC33149.1 xref: EMBL:AAH02796.2 xref: UniProtKB:O76102 xref: UniProtKB:P12980 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018535 ! LYL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055009 name: NR2C1_HUMAN def: "Nuclear receptor subfamily 2 group C member 1" [UniProtKB:P13056] synonym: "Orphan nuclear receptor TR2" EXACT [UniProtKB:P13056] synonym: "Testicular receptor 2" EXACT [UniProtKB:P13056] xref: EMBL:AAA36650.1 xref: UniProtKB:P13056 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018856 ! NR2C1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055010 name: GP1BB_HUMAN def: "Platelet glycoprotein Ib beta chain precursor" [UniProtKB:P13224] synonym: "Antigen CD42b-beta" EXACT [UniProtKB:P13224] synonym: "CD42c antigen" EXACT [UniProtKB:P13224] synonym: "GP-Ib beta" EXACT [UniProtKB:P13224] synonym: "GPIb-beta" EXACT [UniProtKB:P13224] synonym: "GPIbB" EXACT [UniProtKB:P13224] xref: EMBL:AAA20398.1 xref: EMBL:AAA52594.1 xref: EMBL:AAB93437.1 xref: EMBL:AAC39781.1 xref: EMBL:BAC00777.1 xref: UniProtKB:P13224 xref: UniProtKB:Q14422 xref: UniProtKB:Q8NG40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017991 ! GP1BB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0066535 ! GP1BB_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0066536 ! GP1BB_HUMAN-Phosphothreonine193 [Term] id: CCO:B0055011 name: CCL4_HUMAN def: "C-C motif chemokine 4 precursor" [UniProtKB:P13236] synonym: "ACT-2" EXACT [UniProtKB:P13236] synonym: "G-26 T-lymphocyte-secreted protein" EXACT [UniProtKB:P13236] synonym: "HC21" EXACT [UniProtKB:P13236] synonym: "LAG-1" EXACT [UniProtKB:P13236] synonym: "Lymphocyte activation gene 1 protein" EXACT [UniProtKB:P13236] synonym: "Macrophage inflammatory protein 1-beta" EXACT [UniProtKB:P13236] synonym: "MIP-1-beta" EXACT [UniProtKB:P13236] synonym: "MIP-1-beta(1-69)" EXACT [UniProtKB:P13236] synonym: "PAT 744" EXACT [UniProtKB:P13236] synonym: "Protein H400" EXACT [UniProtKB:P13236] synonym: "SIS-gamma" EXACT [UniProtKB:P13236] synonym: "Small-inducible cytokine A4" EXACT [UniProtKB:P13236] synonym: "T-cell activation protein 2" EXACT [UniProtKB:P13236] xref: EMBL:AAA36656.1 xref: EMBL:AAA36752.1 xref: EMBL:AAA51576.1 xref: EMBL:AAA57256.1 xref: EMBL:AAB00790.1 xref: EMBL:AAI04227.1 xref: EMBL:AAI04228.1 xref: EMBL:AAI07434.1 xref: EMBL:AAX07292.1 xref: EMBL:AAX07305.1 xref: EMBL:CAA34291.1 xref: EMBL:CAA37722.2 xref: EMBL:CAA37723.1 xref: EMBL:CAG46916.1 xref: UniProtKB:P13236 xref: UniProtKB:P22617 xref: UniProtKB:Q13704 xref: UniProtKB:Q3SXL8 xref: UniProtKB:Q6FGI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017273 ! CCL4_human relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055012 name: MYF5_HUMAN def: "Myogenic factor 5" [UniProtKB:P13349] synonym: "Myf-5" EXACT [UniProtKB:P13349] xref: EMBL:AAA69824.1 xref: EMBL:AAH69373.1 xref: EMBL:CAA33025.1 xref: EMBL:EAW97368.1 xref: UniProtKB:P13349 xref: UniProtKB:Q6ISR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018696 ! MYF5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000507 ! regulation of cell-matrix adhesion relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055013 name: CCL5_HUMAN def: "C-C motif chemokine 5 precursor" [UniProtKB:P13501] synonym: "EoCP" EXACT [UniProtKB:P13501] synonym: "Eosinophil-chemotactic cytokine" EXACT [UniProtKB:P13501] synonym: "SIS-delta" EXACT [UniProtKB:P13501] synonym: "Small-inducible cytokine A5" EXACT [UniProtKB:P13501] synonym: "T cell-specific protein P228" EXACT [UniProtKB:P13501] synonym: "T-cell-specific protein RANTES" EXACT [UniProtKB:P13501] synonym: "TCP228" EXACT [UniProtKB:P13501] xref: EMBL:AAA36725.1 xref: EMBL:AAC03541.1 xref: EMBL:AAC63331.1 xref: EMBL:AAF73070.1 xref: EMBL:AAH08600.1 xref: EMBL:AAY22177.1 xref: EMBL:ABB69929.1 xref: UniProtKB:O43646 xref: UniProtKB:P13501 xref: UniProtKB:Q0QVW8 xref: UniProtKB:Q4ZGJ1 xref: UniProtKB:Q9NYA2 xref: UniProtKB:Q9UBG2 xref: UniProtKB:Q9UC99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017274 ! CCL5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0005617 ! chemoattractant activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055014 name: SCG2_HUMAN def: "Secretogranin-2 precursor" [UniProtKB:P13521] synonym: "Chromogranin-C" EXACT [UniProtKB:P13521] synonym: "Secretogranin II" EXACT [UniProtKB:P13521] synonym: "SgII" EXACT [UniProtKB:P13521] xref: EMBL:AAA36607.1 xref: EMBL:AAH22509.1 xref: EMBL:AAY24243.1 xref: UniProtKB:P13521 xref: UniProtKB:Q53T11 xref: UniProtKB:Q8TBH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019846 ! SCG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018897 ! ubqln4-scg2 physical interaction relationship: participates_in CCO:I0018902 ! ubqln4-scg2-1 physical interaction relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0070345 ! SCG2_HUMAN-Sulfotyrosine151 relationship: transforms_into CCO:B0070346 ! SCG2_HUMAN-Phosphoserine532 relationship: transforms_into CCO:B0070347 ! SCG2_HUMAN-Phosphoserine533 [Term] id: CCO:B0055015 name: ITA4_HUMAN def: "Integrin alpha-4 precursor" [UniProtKB:P13612] synonym: "CD49 antigen-like family member D" EXACT [UniProtKB:P13612] synonym: "CD49d antigen" EXACT [UniProtKB:P13612] synonym: "Integrin alpha-IV" EXACT [UniProtKB:P13612] synonym: "VLA-4" EXACT [UniProtKB:P13612] xref: EMBL:AAB59613.1 xref: EMBL:CAA34852.1 xref: UniProtKB:P13612 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018334 ! ITGA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016293 ! itga4-itga4-1 physical interaction relationship: participates_in CCO:I0016298 ! itga4-itga4-2 physical interaction relationship: participates_in CCO:I0016304 ! itga4-itgb1-1 physical interaction relationship: participates_in CCO:I0016305 ! itga4-itgb7-2 physical interaction relationship: participates_in CCO:I0016307 ! itgb1-itga4-1 physical interaction relationship: participates_in CCO:I0016309 ! itgb7-itga4-1 physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: transforms_into CCO:B0067159 ! ITA4_HUMAN-Phosphoserine1021 [Term] id: CCO:B0055016 name: AT1A3_HUMAN def: "Sodium/potassium-transporting ATPase subunit alpha-3" [UniProtKB:P13637] synonym: "EC 3.6.3.9" EXACT [UniProtKB:P13637] synonym: "Na(+)/K(+) ATPase alpha(III) subunit" EXACT [UniProtKB:P13637] synonym: "Na(+)/K(+) ATPase alpha-3 subunit" EXACT [UniProtKB:P13637] synonym: "Sodium pump subunit alpha-3" EXACT [UniProtKB:P13637] xref: EMBL:AAA51798.1 xref: EMBL:AAA52285.1 xref: EMBL:AAA52286.1 xref: EMBL:AAA58380.1 xref: EMBL:AAH09282.1 xref: EMBL:AAH09394.1 xref: EMBL:AAH15566.1 xref: EMBL:CAA31390.1 xref: UniProtKB:P13637 xref: UniProtKB:Q16732 xref: UniProtKB:Q16735 xref: UniProtKB:Q969K5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017090 ! ATP1A3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018943 ! atxn1-atp1a3 physical interaction relationship: participates_in CCO:I0018964 ! atxn1-atp1a3-1 physical interaction relationship: participates_in CCO:P0002011 ! ionotropic glutamate receptor signaling pathway relationship: transforms_into CCO:B0063641 ! AT1A3_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: transforms_into CCO:B0063643 ! AT1A3_HUMAN-Phosphotyrosine493 relationship: transforms_into CCO:B0063644 ! AT1A3_HUMAN-Phosphotyrosine548 relationship: transforms_into CCO:B0063645 ! AT1A3_HUMAN-Phosphotyrosine549 relationship: transforms_into CCO:B0063646 ! AT1A3_HUMAN-Phosphoserine933 [Term] id: CCO:B0055017 name: ZNF35_HUMAN def: "Zinc finger protein 35" [UniProtKB:P13682] synonym: "Zinc finger protein HF.10" EXACT [UniProtKB:P13682] xref: EMBL:AAA85451.1 xref: EMBL:AAH13597.2 xref: EMBL:AAP35608.1 xref: EMBL:CAA30268.1 xref: UniProtKB:P13682 xref: UniProtKB:Q53Y54 xref: UniProtKB:Q96D01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020972 ! ZNF35_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055018 name: ONCM_HUMAN def: "Oncostatin-M precursor" [UniProtKB:P13725] synonym: "OSM" EXACT [UniProtKB:P13725] xref: EMBL:AAA36388.1 xref: EMBL:AAC05173.1 xref: EMBL:AAH11589.1 xref: EMBL:CAG30420.1 xref: UniProtKB:P13725 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019046 ! OSM_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001449 ! oncostatin-M receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001795 ! positive regulation of peptidyl-serine phosphorylation relationship: participates_in CCO:P0002068 ! tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002071 ! tyrosine phosphorylation of Stat5 protein relationship: participates_in CCO:P0002073 ! tyrosine phosphorylation of Stat1 protein relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002748 ! negative regulation of hormone secretion relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0055019 name: 2B14_HUMAN def: "HLA class II histocompatibility antigen, DRB1-4 beta chain precursor" [UniProtKB:P13760] synonym: "DR-4" EXACT [UniProtKB:P13760] synonym: "DR4" EXACT [UniProtKB:P13760] synonym: "MHC class I antigen DRB1*4" EXACT [UniProtKB:P13760] xref: EMBL:AAA59805.1 xref: EMBL:AAA59808.1 xref: EMBL:AAA59809.1 xref: EMBL:AAA67104.1 xref: EMBL:AAD29581.1 xref: EMBL:AAF65479.1 xref: EMBL:CAA26660.1 xref: EMBL:CAC08181.1 xref: EMBL:CAC08826.2 xref: EMBL:CAC19360.1 xref: UniProtKB:O19717 xref: UniProtKB:O19739 xref: UniProtKB:P13759 xref: UniProtKB:P13760 xref: UniProtKB:Q29875 xref: UniProtKB:Q30145 xref: UniProtKB:Q9GIX9 xref: UniProtKB:Q9GIY4 xref: UniProtKB:Q9MY13 xref: UniProtKB:Q9XRY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008376 ! HLA-DRB1_human relationship: has_function CCO:F0004979 ! MHC class II receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001670 ! MHC class II protein complex relationship: participates_in CCO:I0019183 ! ha-hla_dra-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055020 name: ADRB3_HUMAN def: "Beta-3 adrenergic receptor" [UniProtKB:P13945] synonym: "Beta-3 adrenoceptor" EXACT [UniProtKB:P13945] synonym: "Beta-3 adrenoreceptor" EXACT [UniProtKB:P13945] xref: EMBL:AAA35550.1 xref: EMBL:AAB24837.1 xref: EMBL:AAH75017.1 xref: EMBL:AAR37414.1 xref: EMBL:AAY88743.1 xref: EMBL:CAA50141.1 xref: EMBL:CAA50142.1 xref: EMBL:CAA50143.1 xref: EMBL:CAA51383.1 xref: UniProtKB:P13945 xref: UniProtKB:Q4JFT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016925 ! ADRB3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001281 ! beta-adrenergic receptor activity relationship: has_function CCO:F0002546 ! beta3-adrenergic receptor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008089 ! norepinephrine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001751 ! receptor complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade [Term] id: CCO:B0055021 name: MIF_HUMAN def: "Macrophage migration inhibitory factor" [UniProtKB:P14174] synonym: "EC 5.3.2.1" EXACT [UniProtKB:P14174] synonym: "GIF" EXACT [UniProtKB:P14174] synonym: "Glycosylation-inhibiting factor" EXACT [UniProtKB:P14174] synonym: "MIF" EXACT [UniProtKB:P14174] synonym: "Phenylpyruvate tautomerase" EXACT [UniProtKB:P14174] xref: EMBL:AAA21814.1 xref: EMBL:AAA35892.1 xref: EMBL:AAA36179.1 xref: EMBL:AAA36315.1 xref: EMBL:AAH00447.1 xref: EMBL:AAH07676.1 xref: EMBL:AAH08914.1 xref: EMBL:AAH13976.1 xref: EMBL:AAH22414.1 xref: EMBL:AAH53376.1 xref: EMBL:AAL78635.1 xref: EMBL:AAP35812.1 xref: EMBL:ABB96245.1 xref: EMBL:CAA80598.1 xref: EMBL:CAG28572.1 xref: EMBL:CAG30406.1 xref: UniProtKB:P14174 xref: UniProtKB:Q2V4Y5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018623 ! MIF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015146 ! gorasp2-mif physical interaction relationship: participates_in CCO:I0017344 ! znf408-mif physical interaction relationship: participates_in CCO:I0020674 ! strn4-mif physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002142 ! regulation of macrophage activation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0068186 ! MIF_HUMAN-Phosphotyrosine37 [Term] id: CCO:B0055022 name: IRF2_HUMAN def: "Interferon regulatory factor 2" [UniProtKB:P14316] synonym: "IRF-2" EXACT [UniProtKB:P14316] xref: EMBL:AAH15803.1 xref: EMBL:CAA34073.1 xref: UniProtKB:P14316 xref: UniProtKB:Q96B99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018312 ! IRF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055023 name: HCLS1_HUMAN def: "Hematopoietic lineage cell-specific protein" [UniProtKB:P14317] synonym: "Hematopoietic cell-specific LYN substrate 1" EXACT [UniProtKB:P14317] synonym: "LckBP1" EXACT [UniProtKB:P14317] synonym: "p75" EXACT [UniProtKB:P14317] xref: EMBL:AAH16758.1 xref: EMBL:CAA34651.1 xref: UniProtKB:P14317 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018108 ! HCLS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: transforms_into CCO:B0066769 ! HCLS1_HUMAN-Phosphotyrosine103 relationship: transforms_into CCO:B0066770 ! HCLS1_HUMAN-Phosphotyrosine140 relationship: transforms_into CCO:B0066771 ! HCLS1_HUMAN-Phosphotyrosine198 relationship: transforms_into CCO:B0066772 ! HCLS1_HUMAN-Phosphotyrosine222 relationship: transforms_into CCO:B0066773 ! HCLS1_HUMAN-Phosphoserine275 [Term] id: CCO:B0055024 name: DRD2_HUMAN def: "D(2) dopamine receptor" [UniProtKB:P14416] synonym: "Dopamine D2 receptor" EXACT [UniProtKB:P14416] xref: EMBL:AAA52761.1 xref: EMBL:AAA88024.1 xref: EMBL:AAB20571.1 xref: EMBL:AAB26274.1 xref: EMBL:AAB26819.1 xref: EMBL:AAC78779.1 xref: EMBL:AAF61479.1 xref: EMBL:AAH21195.1 xref: EMBL:BAC06078.1 xref: EMBL:CAA35746.1 xref: EMBL:CAB37869.1 xref: EMBL:CAB56463.1 xref: UniProtKB:P14416 xref: UniProtKB:Q9NZR3 xref: UniProtKB:Q9UPA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017618 ! DRD2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000733 ! dopamine receptor, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway relationship: participates_in CCO:P0003263 ! dopamine receptor, phospholipase C activating pathway [Term] id: CCO:B0055025 name: ENPL_HUMAN def: "Endoplasmin precursor" [UniProtKB:P14625] synonym: "94 kDa glucose-regulated protein" EXACT [UniProtKB:P14625] synonym: "gp96 homolog" EXACT [UniProtKB:P14625] synonym: "GRP94" EXACT [UniProtKB:P14625] synonym: "Heat shock protein 90 kDa beta member 1" EXACT [UniProtKB:P14625] synonym: "Tumor rejection antigen 1" EXACT [UniProtKB:P14625] xref: EMBL:AAA58621.1 xref: EMBL:AAA68201.1 xref: EMBL:AAH66656.1 xref: EMBL:AAK74072.1 xref: EMBL:CAA33261.1 xref: UniProtKB:P14625 xref: UniProtKB:Q96A97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017713 ! HSP90B1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0006246 ! virion binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0017051 ! tnfrsf1b-tra1 physical interaction relationship: participates_in CCO:I0018399 ! grp94-pek-1 physical interaction relationship: participates_in CCO:I0019518 ! ldlr-hsp90b1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0065074 ! ENPL_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0065075 ! ENPL_HUMAN-Phosphotyrosine677 [Term] id: CCO:B0055026 name: HXB3_HUMAN def: "Homeobox protein Hox-B3" [UniProtKB:P14651] synonym: "Hox-2.7" EXACT [UniProtKB:P14651] synonym: "Hox-2G" EXACT [UniProtKB:P14651] xref: EMBL:AAD10852.1 xref: EMBL:AAG31555.1 xref: EMBL:BAF83871.1 xref: EMBL:BAG37563.1 xref: EMBL:CAA34297.1 xref: EMBL:CAA34657.1 xref: UniProtKB:A8K567 xref: UniProtKB:O95615 xref: UniProtKB:P14651 xref: UniProtKB:P17484 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018184 ! HOXB3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055027 name: HXB2_HUMAN def: "Homeobox protein Hox-B2" [UniProtKB:P14652] synonym: "Hox-2.8" EXACT [UniProtKB:P14652] synonym: "Hox-2H" EXACT [UniProtKB:P14652] synonym: "K8" EXACT [UniProtKB:P14652] xref: EMBL:AAH74805.1 xref: EMBL:AAH74806.1 xref: EMBL:CAA32709.1 xref: EMBL:CAA34298.1 xref: EMBL:CAA34655.1 xref: EMBL:CAA55581.1 xref: UniProtKB:P10913 xref: UniProtKB:P14652 xref: UniProtKB:P17485 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018183 ! HOXB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066962 ! HXB2_HUMAN-Phosphothreonine52 relationship: transforms_into CCO:B0066963 ! HXB2_HUMAN-Phosphoserine55 [Term] id: CCO:B0055028 name: HXB1_HUMAN def: "Homeobox protein Hox-B1" [UniProtKB:P14653] synonym: "Hox-2I" EXACT [UniProtKB:P14653] xref: EMBL:CAA34656.1 xref: UniProtKB:P14653 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012009 ! HOXB1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017279 ! hoxb1-pbx1-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055029 name: MMP9_HUMAN def: "Matrix metalloproteinase-9 precursor" [UniProtKB:P14780] synonym: "92 kDa gelatinase" EXACT [UniProtKB:P14780] synonym: "92 kDa type IV collagenase" EXACT [UniProtKB:P14780] synonym: "EC 3.4.24.35" EXACT [UniProtKB:P14780] synonym: "Gelatinase B" EXACT [UniProtKB:P14780] synonym: "GELB" EXACT [UniProtKB:P14780] synonym: "MMP-9" EXACT [UniProtKB:P14780] xref: EMBL:AAA51539.1 xref: EMBL:AAH06093.1 xref: EMBL:AAM97934.1 xref: EMBL:ABA03169.1 xref: EMBL:BAA20967.1 xref: EMBL:CAC10459.1 xref: UniProtKB:P14780 xref: UniProtKB:Q3LR70 xref: UniProtKB:Q8N725 xref: UniProtKB:Q9H4Z1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018640 ! MMP9_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0000679 ! gelatinase B activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_function CCO:F0001737 ! collagenase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0055030 name: LIF_HUMAN def: "Leukemia inhibitory factor precursor" [UniProtKB:P15018] synonym: "D factor" EXACT [UniProtKB:P15018] synonym: "Differentiation-stimulating factor" EXACT [UniProtKB:P15018] synonym: "Emfilermin" EXACT [UniProtKB:P15018] synonym: "LIF" EXACT [UniProtKB:P15018] synonym: "Melanoma-derived LPL inhibitor" EXACT [UniProtKB:P15018] synonym: "MLPLI" EXACT [UniProtKB:P15018] xref: EMBL:AAA51699.1 xref: EMBL:AAA53188.1 xref: EMBL:AAA59517.1 xref: EMBL:AAC05174.1 xref: EMBL:AAH69540.1 xref: EMBL:AAH93733.1 xref: EMBL:AAH93735.1 xref: EMBL:CAA32147.1 xref: UniProtKB:P15018 xref: UniProtKB:Q52LZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018493 ! LIF_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001448 ! leukemia inhibitory factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0017786 ! il6st-lif-1 direct interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001795 ! positive regulation of peptidyl-serine phosphorylation relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002465 ! positive regulation of macrophage differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002748 ! negative regulation of hormone secretion relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0055031 name: MYOG_HUMAN def: "Myogenin" [UniProtKB:P15173] synonym: "Myf-4" EXACT [UniProtKB:P15173] synonym: "Myogenic factor 4" EXACT [UniProtKB:P15173] xref: EMBL:AAH53899.1 xref: EMBL:CAA35641.1 xref: EMBL:CAA44080.1 xref: UniProtKB:P15173 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018700 ! MYOG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055032 name: IL9_HUMAN def: "Interleukin-9 precursor" [UniProtKB:P15248] synonym: "IL-9" EXACT [UniProtKB:P15248] synonym: "P40 cytokine" EXACT [UniProtKB:P15248] synonym: "T-cell growth factor P40" EXACT [UniProtKB:P15248] xref: EMBL:AAA35887.1 xref: EMBL:AAA36400.1 xref: EMBL:AAA59161.1 xref: EMBL:AAB19823.1 xref: EMBL:AAB66904.1 xref: EMBL:AAC17735.1 xref: EMBL:AAH66283.1 xref: EMBL:AAH66285.1 xref: EMBL:AAH66286.1 xref: EMBL:AAK26666.1 xref: EMBL:CAA35581.1 xref: UniProtKB:P15248 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018272 ! IL9_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002348 ! positive regulation of interleukin-5 biosynthetic process [Term] id: CCO:B0055033 name: INGR1_HUMAN def: "Interferon-gamma receptor alpha chain precursor" [UniProtKB:P15260] synonym: "CD119 antigen" EXACT [UniProtKB:P15260] synonym: "CDw119" EXACT [UniProtKB:P15260] synonym: "IFN-gamma-R1" EXACT [UniProtKB:P15260] xref: EMBL:AAA52731.1 xref: EMBL:AAH05333.1 xref: EMBL:AAS89302.1 xref: EMBL:CAB53062.1 xref: UniProtKB:P15260 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018285 ! IFNGR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008966 ! ifng-ifngr1-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067114 ! INGR1_HUMAN-Phosphoserine369 [Term] id: CCO:B0055034 name: B4GT1_HUMAN def: "Beta-1,4-galactosyltransferase 1" [UniProtKB:P15291] synonym: "b4Gal-T1" EXACT [UniProtKB:P15291] synonym: "Beta-1,4-GalTase 1" EXACT [UniProtKB:P15291] synonym: "Beta4Gal-T1" EXACT [UniProtKB:P15291] synonym: "EC 2.4.1.-" EXACT [UniProtKB:P15291] synonym: "UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1" EXACT [UniProtKB:P15291] synonym: "UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1" EXACT [UniProtKB:P15291] xref: EMBL:AAA35935.1 xref: EMBL:AAA35936.1 xref: EMBL:AAA35937.1 xref: EMBL:AAA68218.1 xref: EMBL:AAA68219.1 xref: EMBL:AAA68220.1 xref: EMBL:AAB00776.1 xref: EMBL:BAA06188.1 xref: EMBL:CAA31611.1 xref: EMBL:CAA32247.1 xref: EMBL:CAA39073.1 xref: EMBL:CAA39074.1 xref: EMBL:CAD13306.1 xref: UniProtKB:P15291 xref: UniProtKB:Q12909 xref: UniProtKB:Q12910 xref: UniProtKB:Q12911 xref: UniProtKB:Q14456 xref: UniProtKB:Q14509 xref: UniProtKB:Q14523 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017111 ! B4GALT1_human relationship: has_function CCO:F0000350 ! beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity relationship: has_function CCO:F0000439 ! N-acetyllactosamine synthase activity relationship: has_function CCO:F0000861 ! lactose synthase activity relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0001853 ! galactosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005579 ! UDP-galactosyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000020 ! Golgi trans cisterna relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000939 ! desmosome relationship: located_in CCO:C0000959 ! glycocalyx relationship: located_in CCO:C0001290 ! brush border membrane relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0003071 ! regulation of cell motility relationship: participates_in CCO:P0003238 ! positive regulation of epithelial cell proliferation involved in wound healing relationship: participates_in CCO:P0003239 ! positive regulation of apoptosis involved in mammary gland involution [Term] id: CCO:B0055035 name: CD19_HUMAN def: "B-lymphocyte antigen CD19 precursor" [UniProtKB:P15391] synonym: "B-lymphocyte surface antigen B4" EXACT [UniProtKB:P15391] synonym: "CD19 antigen" EXACT [UniProtKB:P15391] synonym: "Differentiation antigen CD19" EXACT [UniProtKB:P15391] synonym: "Leu-12" EXACT [UniProtKB:P15391] xref: EMBL:AAA35533.1 xref: EMBL:AAA68490.1 xref: EMBL:AAA69966.1 xref: EMBL:AAB60697.1 xref: EMBL:AAH06338.1 xref: EMBL:BAB60954.1 xref: UniProtKB:P15391 xref: UniProtKB:Q96S68 xref: UniProtKB:Q9BRD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017287 ! CD19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017643 ! p55g-cd19-1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0064133 ! CD19_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0064134 ! CD19_HUMAN-Phosphotyrosine348 relationship: transforms_into CCO:B0064135 ! CD19_HUMAN-Phosphotyrosine378 relationship: transforms_into CCO:B0064136 ! CD19_HUMAN-Phosphotyrosine409 relationship: transforms_into CCO:B0064137 ! CD19_HUMAN-Phosphotyrosine439 relationship: transforms_into CCO:B0064138 ! CD19_HUMAN-Phosphoserine497 [Term] id: CCO:B0055036 name: FOSL2_HUMAN def: "Fos-related antigen 2" [UniProtKB:P15408] xref: EMBL:AAH22791.1 xref: EMBL:CAA34678.1 xref: UniProtKB:P15408 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017820 ! FOSL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0066246 ! FOSL2_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0066247 ! FOSL2_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0066248 ! FOSL2_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0066249 ! FOSL2_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0066250 ! FOSL2_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0066251 ! FOSL2_HUMAN-Phosphoserine320 [Term] id: CCO:B0055037 name: VAV_HUMAN def: "Proto-oncogene vav" [UniProtKB:P15498] xref: EMBL:AAA63267.1 xref: EMBL:AAC25011.1 xref: EMBL:CAA34383.1 xref: EMBL:CAA58783.1 xref: UniProtKB:P15498 xref: UniProtKB:Q15860 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020436 ! VAV1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017374 ! zn655-vav1-4 physical interaction relationship: participates_in CCO:I0017375 ! zn655-vav1-5 physical interaction relationship: participates_in CCO:I0017743 ! zn655-vav1-1 physical interaction relationship: participates_in CCO:I0018320 ! zn655-vav1-2 physical interaction relationship: participates_in CCO:I0018644 ! zn655-vav1-3 physical interaction relationship: participates_in CCO:I0018645 ! grb2-vav1-1 physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion relationship: transforms_into CCO:B0071790 ! VAV_HUMAN-Phosphotyrosine826 relationship: transforms_into CCO:B0071791 ! VAV_HUMAN-Phosphotyrosine844 [Term] id: CCO:B0055038 name: ELN_HUMAN def: "Elastin precursor" [UniProtKB:P15502] synonym: "Tropoelastin" EXACT [UniProtKB:P15502] xref: EMBL:AAA52382.1 xref: EMBL:AAA53190.1 xref: EMBL:AAB17544.1 xref: EMBL:AAB65620.1 xref: EMBL:AAB65621.1 xref: EMBL:AAC13884.1 xref: EMBL:AAC98393.1 xref: EMBL:AAC98394.1 xref: EMBL:AAC98395.1 xref: EMBL:AAH65566.1 xref: EMBL:AAS07435.1 xref: EMBL:BAC85506.1 xref: EMBL:CAA33627.1 xref: EMBL:CAD97910.1 xref: EMBL:CAD98065.1 xref: UniProtKB:O15336 xref: UniProtKB:O15337 xref: UniProtKB:P15502 xref: UniProtKB:Q14233 xref: UniProtKB:Q14234 xref: UniProtKB:Q14235 xref: UniProtKB:Q14238 xref: UniProtKB:Q6P0L4 xref: UniProtKB:Q6ZWJ6 xref: UniProtKB:Q75MU5 xref: UniProtKB:Q7Z316 xref: UniProtKB:Q7Z3F5 xref: UniProtKB:Q9UMF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017692 ! ELN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0064985 ! ELN_HUMAN-Hydroxyproline34 relationship: transforms_into CCO:B0064986 ! ELN_HUMAN-Hydroxyproline65 relationship: transforms_into CCO:B0064987 ! ELN_HUMAN-Hydroxyproline67 relationship: transforms_into CCO:B0064988 ! ELN_HUMAN-Hydroxyproline88 relationship: transforms_into CCO:B0064989 ! ELN_HUMAN-Allysine104 relationship: transforms_into CCO:B0064990 ! ELN_HUMAN-4-hydroxyproline116 relationship: transforms_into CCO:B0064991 ! ELN_HUMAN-Hydroxyproline156 relationship: transforms_into CCO:B0064992 ! ELN_HUMAN-Hydroxyproline167 relationship: transforms_into CCO:B0064993 ! ELN_HUMAN-Hydroxyproline170 relationship: transforms_into CCO:B0064994 ! ELN_HUMAN-Hydroxyproline177 relationship: transforms_into CCO:B0064995 ! ELN_HUMAN-4-hydroxyproline190 relationship: transforms_into CCO:B0064996 ! ELN_HUMAN-Allysine241 relationship: transforms_into CCO:B0064997 ! ELN_HUMAN-Allysine261 relationship: transforms_into CCO:B0064998 ! ELN_HUMAN-Allysine265 relationship: transforms_into CCO:B0064999 ! ELN_HUMAN-4-hydroxyproline283 relationship: transforms_into CCO:B0065000 ! ELN_HUMAN-4-hydroxyproline286 relationship: transforms_into CCO:B0065001 ! ELN_HUMAN-Hydroxyproline290 relationship: transforms_into CCO:B0065002 ! ELN_HUMAN-Allysine312 relationship: transforms_into CCO:B0065003 ! ELN_HUMAN-Allysine315 relationship: transforms_into CCO:B0065004 ! ELN_HUMAN-4-hydroxyproline327 relationship: transforms_into CCO:B0065005 ! ELN_HUMAN-4-hydroxyproline342 relationship: transforms_into CCO:B0065006 ! ELN_HUMAN-4-hydroxyproline347 relationship: transforms_into CCO:B0065007 ! ELN_HUMAN-Hydroxyproline352 relationship: transforms_into CCO:B0065008 ! ELN_HUMAN-Hydroxyproline355 relationship: transforms_into CCO:B0065009 ! ELN_HUMAN-4-hydroxyproline360 relationship: transforms_into CCO:B0065010 ! ELN_HUMAN-Allysine375 relationship: transforms_into CCO:B0065011 ! ELN_HUMAN-Allysine379 relationship: transforms_into CCO:B0065012 ! ELN_HUMAN-Allysine382 relationship: transforms_into CCO:B0065013 ! ELN_HUMAN-4-hydroxyproline415 relationship: transforms_into CCO:B0065014 ! ELN_HUMAN-Hydroxyproline421 relationship: transforms_into CCO:B0065015 ! ELN_HUMAN-4-hydroxyproline427 relationship: transforms_into CCO:B0065016 ! ELN_HUMAN-Allysine451 relationship: transforms_into CCO:B0065017 ! ELN_HUMAN-Hydroxyproline465 relationship: transforms_into CCO:B0065018 ! ELN_HUMAN-Hydroxyproline467 relationship: transforms_into CCO:B0065019 ! ELN_HUMAN-4-hydroxyproline481 relationship: transforms_into CCO:B0065020 ! ELN_HUMAN-Allysine492 relationship: transforms_into CCO:B0065021 ! ELN_HUMAN-Allysine496 relationship: transforms_into CCO:B0065022 ! ELN_HUMAN-Hydroxyproline522 relationship: transforms_into CCO:B0065023 ! ELN_HUMAN-Hydroxyproline550 relationship: transforms_into CCO:B0065024 ! ELN_HUMAN-Allysine558 relationship: transforms_into CCO:B0065025 ! ELN_HUMAN-Allysine562 relationship: transforms_into CCO:B0065026 ! ELN_HUMAN-Allysine566 relationship: transforms_into CCO:B0065027 ! ELN_HUMAN-4-hydroxyproline580 relationship: transforms_into CCO:B0065028 ! ELN_HUMAN-4-hydroxyproline589 relationship: transforms_into CCO:B0065029 ! ELN_HUMAN-4-hydroxyproline598 relationship: transforms_into CCO:B0065030 ! ELN_HUMAN-4-hydroxyproline607 relationship: transforms_into CCO:B0065031 ! ELN_HUMAN-Hydroxyproline646 relationship: transforms_into CCO:B0065032 ! ELN_HUMAN-Allysine653 relationship: transforms_into CCO:B0065033 ! ELN_HUMAN-Allysine656 relationship: transforms_into CCO:B0065034 ! ELN_HUMAN-4-hydroxyproline677 relationship: transforms_into CCO:B0065035 ! ELN_HUMAN-Allysine693 relationship: transforms_into CCO:B0065036 ! ELN_HUMAN-Allysine697 relationship: transforms_into CCO:B0065037 ! ELN_HUMAN-Allysine735 relationship: transforms_into CCO:B0065038 ! ELN_HUMAN-Allysine738 relationship: transforms_into CCO:B0065039 ! ELN_HUMAN-Hydroxyproline769 relationship: transforms_into CCO:B0065040 ! ELN_HUMAN-Hydroxyproline772 [Term] id: CCO:B0055039 name: AREG_HUMAN def: "Amphiregulin precursor" [UniProtKB:P15514] synonym: "AR" EXACT [UniProtKB:P15514] synonym: "Colorectum cell-derived growth factor" EXACT [UniProtKB:P15514] synonym: "CRDGF" EXACT [UniProtKB:P15514] xref: EMBL:AAA51773.1 xref: EMBL:AAA51781.1 xref: EMBL:AAH09799.1 xref: EMBL:AAR05438.1 xref: UniProtKB:P15514 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017002 ! AREG_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017523 ! areg-ubqln4 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055040 name: ZNF44_HUMAN def: "Zinc finger protein 44" [UniProtKB:P15621] synonym: "GIOT-2" EXACT [UniProtKB:P15621] synonym: "Gonadotropin-inducible transcription repressor 2" EXACT [UniProtKB:P15621] synonym: "Zinc finger protein 58" EXACT [UniProtKB:P15621] synonym: "Zinc finger protein KOX7" EXACT [UniProtKB:P15621] xref: EMBL:BAA86988.1 xref: EMBL:BAG59931.1 xref: EMBL:CAA34357.1 xref: EMBL:CAA36564.1 xref: UniProtKB:B4DML9 xref: UniProtKB:P15621 xref: UniProtKB:P17018 xref: UniProtKB:Q9ULZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020976 ! ZNF44_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018460 ! csnk2b-znf44 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072256 ! ZNF44_HUMAN-Phosphoserine427 [Term] id: CCO:B0055041 name: ZN250_HUMAN def: "Zinc finger protein 250" [UniProtKB:P15622] synonym: "Zinc finger protein 647" EXACT [UniProtKB:P15622] xref: EMBL:AAH17091.2 xref: EMBL:BAC04614.1 xref: EMBL:CAA34358.1 xref: UniProtKB:P15622 xref: UniProtKB:Q8N942 xref: UniProtKB:Q96AH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020678 ! ZNF250_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015098 ! krtap4_12-znf250 physical interaction relationship: participates_in CCO:I0015115 ! golga2-znf250 physical interaction relationship: participates_in CCO:I0015186 ! begain-znf250 physical interaction relationship: participates_in CCO:I0015270 ! hook1-znf250 physical interaction relationship: participates_in CCO:I0015359 ! ldoc1-znf250 physical interaction relationship: participates_in CCO:I0015370 ! hook2-znf250 physical interaction relationship: participates_in CCO:I0015733 ! dvl2-znf250 physical interaction relationship: participates_in CCO:I0015752 ! trim23-znf250 physical interaction relationship: participates_in CCO:I0015769 ! q96br9-znf250 physical interaction relationship: participates_in CCO:I0015808 ! znf165-znf250 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055042 name: ZEP1_HUMAN def: "Zinc finger protein 40" [UniProtKB:P15822] synonym: "HIV-EP1" EXACT [UniProtKB:P15822] synonym: "Human immunodeficiency virus type I enhancer-binding protein 1" EXACT [UniProtKB:P15822] synonym: "Major histocompatibility complex-binding protein 1" EXACT [UniProtKB:P15822] synonym: "MBP-1" EXACT [UniProtKB:P15822] synonym: "Positive regulatory domain II-binding factor 1" EXACT [UniProtKB:P15822] synonym: "PRDII-BF1" EXACT [UniProtKB:P15822] xref: EMBL:AAA17534.1 xref: EMBL:CAA35798.1 xref: EMBL:CAH73909.1 xref: EMBL:CAH73982.1 xref: EMBL:CAI14768.1 xref: EMBL:CAI21070.1 xref: UniProtKB:P15822 xref: UniProtKB:Q14122 xref: UniProtKB:Q5VW60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008684 ! HIVEP1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0016181 ! atxn1-hivep1 physical interaction relationship: participates_in CCO:I0018910 ! aptx-hivep1 physical interaction relationship: participates_in CCO:I0018953 ! atxn1-hivep1-1 physical interaction relationship: participates_in CCO:I0018974 ! atxn1-hivep1-2 physical interaction relationship: participates_in CCO:I0018994 ! atxn1-hivep1-3 physical interaction relationship: participates_in CCO:I0019041 ! atxn1-hivep1-4 physical interaction relationship: participates_in CCO:I0020423 ! rab1a-hivep1 physical interaction relationship: participates_in CCO:I0020521 ! c2f-hivep1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071992 ! ZEP1_HUMAN-Phosphoserine1051 relationship: transforms_into CCO:B0071993 ! ZEP1_HUMAN-Phosphoserine1873 relationship: transforms_into CCO:B0071994 ! ZEP1_HUMAN-Phosphoserine1874 [Term] id: CCO:B0055043 name: PAX1_HUMAN def: "Paired box protein Pax-1" [UniProtKB:P15863] synonym: "HUP48" EXACT [UniProtKB:P15863] xref: EMBL:AAH69134.1 xref: EMBL:AAU21037.1 xref: EMBL:CAA33146.1 xref: EMBL:CAB46996.1 xref: UniProtKB:P15863 xref: UniProtKB:Q642X9 xref: UniProtKB:Q6NTC0 xref: UniProtKB:Q9Y558 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019305 ! PAX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055044 name: CHIN_HUMAN def: "N-chimaerin" [UniProtKB:P15882] synonym: "A-chimaerin" EXACT [UniProtKB:P15882] synonym: "Alpha-chimerin" EXACT [UniProtKB:P15882] synonym: "N-chimerin" EXACT [UniProtKB:P15882] synonym: "NC" EXACT [UniProtKB:P15882] synonym: "Rho GTPase-activating protein 2" EXACT [UniProtKB:P15882] xref: EMBL:AAB33506.1 xref: EMBL:AAH11393.1 xref: EMBL:AAY14688.1 xref: EMBL:AAY14940.1 xref: EMBL:CAA35769.1 xref: EMBL:CAA80354.1 xref: UniProtKB:P15882 xref: UniProtKB:Q53SD6 xref: UniProtKB:Q53SH5 xref: UniProtKB:Q96FB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017354 ! CHN1_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0020275 ! chn1-gtf3c1 physical interaction relationship: participates_in CCO:I0020276 ! chn1-rps3a physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055045 name: GATA1_HUMAN def: "Erythroid transcription factor" [UniProtKB:P15976] synonym: "Eryf1" EXACT [UniProtKB:P15976] synonym: "GATA-1" EXACT [UniProtKB:P15976] synonym: "GATA-binding factor 1" EXACT [UniProtKB:P15976] synonym: "GF-1" EXACT [UniProtKB:P15976] synonym: "NF-E1 DNA-binding protein" EXACT [UniProtKB:P15976] xref: EMBL:AAA35885.1 xref: EMBL:AAH09797.1 xref: EMBL:CAA35120.1 xref: UniProtKB:P15976 xref: UniProtKB:Q96GB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017869 ! GATA1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055046 name: TIMP2_HUMAN def: "Metalloproteinase inhibitor 2 precursor" [UniProtKB:P16035] synonym: "CSC-21K" EXACT [UniProtKB:P16035] synonym: "TIMP-2" EXACT [UniProtKB:P16035] synonym: "Tissue inhibitor of metalloproteinases 2" EXACT [UniProtKB:P16035] xref: EMBL:AAA59581.1 xref: EMBL:AAA61186.1 xref: EMBL:AAB19474.1 xref: EMBL:AAC50729.1 xref: EMBL:AAD14025.1 xref: EMBL:AAH52605.1 xref: EMBL:AAH71586.1 xref: EMBL:CAA38400.1 xref: UniProtKB:P16035 xref: UniProtKB:Q16121 xref: UniProtKB:Q93006 xref: UniProtKB:Q9UDF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020273 ! TIMP2_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001771 ! metalloendopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0019477 ! mmp2-timp2-1 direct interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001307 ! regulation of cAMP metabolic process relationship: participates_in CCO:P0002209 ! regulation of MAPKKK cascade relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation [Term] id: CCO:B0055047 name: LEUK_HUMAN def: "Leukosialin precursor" [UniProtKB:P16150] synonym: "CD43 antigen" EXACT [UniProtKB:P16150] synonym: "Galactoglycoprotein" EXACT [UniProtKB:P16150] synonym: "GALGP" EXACT [UniProtKB:P16150] synonym: "Leukocyte sialoglycoprotein" EXACT [UniProtKB:P16150] synonym: "Sialophorin" EXACT [UniProtKB:P16150] xref: EMBL:AAA51949.1 xref: EMBL:AAA59510.1 xref: EMBL:AAB59540.1 xref: EMBL:AAH12350.1 xref: EMBL:CAA36294.1 xref: UniProtKB:P16150 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018475 ! SPN_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001847 ! bacterial binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000189 ! uropod relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0001401 ! T cell costimulation relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation relationship: participates_in CCO:P0002099 ! positive regulation of tumor necrosis factor biosynthetic process relationship: transforms_into CCO:B0067642 ! LEUK_HUMAN-Phosphoserine355 [Term] id: CCO:B0055048 name: NCK1_HUMAN def: "Cytoplasmic protein NCK1" [UniProtKB:P16333] synonym: "NCK adaptor protein 1" EXACT [UniProtKB:P16333] synonym: "Nck-1" EXACT [UniProtKB:P16333] synonym: "SH2/SH3 adaptor protein NCK-alpha" EXACT [UniProtKB:P16333] xref: EMBL:AAH06403.1 xref: EMBL:CAA35599.1 xref: UniProtKB:P16333 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018725 ! NCK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016151 ! nck1-waspip-3 physical interaction relationship: participates_in CCO:I0016339 ! nck1-nphs1 physical interaction relationship: participates_in CCO:I0016340 ! nck1-nphs1-1 physical interaction relationship: participates_in CCO:I0017395 ! nck-sos1-1 physical interaction relationship: participates_in CCO:I0017396 ! nck-dnm1-2 physical interaction relationship: participates_in CCO:I0017910 ! nck1-waspip-2 physical interaction relationship: participates_in CCO:I0017911 ! nck-dnm1-3 physical interaction relationship: participates_in CCO:I0018108 ! nphs1-nck1 physical interaction relationship: participates_in CCO:I0018769 ! abi1-nck1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: participates_in CCO:P0001331 ! positive regulation of actin filament polymerization relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: transforms_into CCO:B0068462 ! NCK1_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0068463 ! NCK1_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0068464 ! NCK1_HUMAN-Phosphotyrosine105 [Term] id: CCO:B0055049 name: GCF_HUMAN def: "GC-rich sequence DNA-binding factor" [UniProtKB:P16383] synonym: "GCF" EXACT [UniProtKB:P16383] synonym: "TCF-9" EXACT [UniProtKB:P16383] synonym: "Transcription factor 9" EXACT [UniProtKB:P16383] xref: EMBL:AAA35598.1 xref: EMBL:AAH64559.1 xref: EMBL:AAY14973.1 xref: UniProtKB:O95032 xref: UniProtKB:P16383 xref: UniProtKB:Q53TY0 xref: UniProtKB:Q6P2F2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017893 ! TCF9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066415 ! GCF_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0066416 ! GCF_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0066417 ! GCF_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0066418 ! GCF_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0066419 ! GCF_HUMAN-Phosphothreonine97 relationship: transforms_into CCO:B0066420 ! GCF_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0066421 ! GCF_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0066422 ! GCF_HUMAN-Phosphoserine429 relationship: transforms_into CCO:B0066423 ! GCF_HUMAN-Phosphoserine430 [Term] id: CCO:B0055050 name: ZN823_HUMAN def: "Zinc finger protein 823" [UniProtKB:P16415] synonym: "Zinc finger protein ZFP-36" EXACT [UniProtKB:P16415] xref: EMBL:AAH52597.1 xref: EMBL:AAH63560.1 xref: EMBL:CAA36064.1 xref: UniProtKB:A0PJL4 xref: UniProtKB:P16415 xref: UniProtKB:Q6P4A9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020953 ! ZNF823_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055051 name: EPB42_HUMAN def: "Erythrocyte membrane protein band 4.2" [UniProtKB:P16452] synonym: "Erythrocyte protein 4.2" EXACT [UniProtKB:P16452] synonym: "P4.2" EXACT [UniProtKB:P16452] xref: EMBL:AAA35798.1 xref: EMBL:AAA36401.1 xref: EMBL:AAA36402.1 xref: EMBL:AAA52385.1 xref: EMBL:AAA74589.1 xref: UniProtKB:P16452 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017720 ! EPB42_human relationship: has_function CCO:F0000335 ! protein-glutamine gamma-glutamyltransferase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0018725 ! spink7-ebp42 physical interaction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0065086 ! EPB42_HUMAN-Phosphoserine248 [Term] id: CCO:B0055052 name: MGMT_HUMAN def: "Methylated-DNA--protein-cysteine methyltransferase" [UniProtKB:P16455] synonym: "6-O-methylguanine-DNA methyltransferase" EXACT [UniProtKB:P16455] synonym: "EC 2.1.1.63" EXACT [UniProtKB:P16455] synonym: "MGMT" EXACT [UniProtKB:P16455] synonym: "O-6-methylguanine-DNA-alkyltransferase" EXACT [UniProtKB:P16455] xref: EMBL:AAA52317.1 xref: EMBL:AAA59594.1 xref: EMBL:AAA59596.1 xref: EMBL:AAH00824.1 xref: EMBL:AAP35360.1 xref: EMBL:CAA38137.1 xref: EMBL:CAH70060.1 xref: EMBL:CAH72190.1 xref: EMBL:EAW49166.1 xref: UniProtKB:P16455 xref: UniProtKB:Q5VY78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018611 ! MGMT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002179 ! regulation of caspase activity relationship: transforms_into CCO:B0068159 ! MGMT_HUMAN-Phosphothreonine10 relationship: transforms_into CCO:B0068160 ! MGMT_HUMAN-Phosphothreonine11 relationship: transforms_into CCO:B0068161 ! MGMT_HUMAN-Phosphoserine201 [Term] id: CCO:B0055053 name: PRLR_HUMAN def: "Prolactin receptor precursor" [UniProtKB:P16471] synonym: "PRL-R" EXACT [UniProtKB:P16471] xref: EMBL:AAA60174.1 xref: EMBL:AAB34470.1 xref: EMBL:AAD32032.1 xref: EMBL:AAD49855.1 xref: EMBL:AAH59392.1 xref: EMBL:AAK32703.1 xref: EMBL:AAL23914.1 xref: EMBL:AAL23915.1 xref: EMBL:AAM11661.1 xref: EMBL:AAM18048.1 xref: UniProtKB:P16471 xref: UniProtKB:Q16354 xref: UniProtKB:Q8TD75 xref: UniProtKB:Q8TD78 xref: UniProtKB:Q96P35 xref: UniProtKB:Q96P36 xref: UniProtKB:Q9BX87 xref: UniProtKB:Q9UHJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019512 ! PRLR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001270 ! prolactin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005776 ! ornithine decarboxylase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017812 ! gh1-prlr-1 direct interaction relationship: participates_in CCO:I0018778 ! nek3-prlr-1 physical interaction relationship: participates_in CCO:I0018780 ! vav2-prlr-1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000713 ! activation of transmembrane receptor protein tyrosine kinase activity relationship: participates_in CCO:P0002130 ! activation of JAK2 kinase activity [Term] id: CCO:B0055054 name: TSHR_HUMAN def: "Thyrotropin receptor precursor" [UniProtKB:P16473] synonym: "Thyroid-stimulating hormone receptor" EXACT [UniProtKB:P16473] synonym: "TSH-R" EXACT [UniProtKB:P16473] xref: EMBL:AAA36783.1 xref: EMBL:AAA61236.1 xref: EMBL:AAA70232.1 xref: EMBL:AAB23390.2 xref: EMBL:AAD31568.1 xref: EMBL:AAF09032.1 xref: EMBL:AAF26775.1 xref: EMBL:AAR07906.1 xref: UniProtKB:P16473 xref: UniProtKB:Q9P1V4 xref: UniProtKB:Q9ULA3 xref: UniProtKB:Q9UPH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020373 ! TSHR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001334 ! thyroid-stimulating hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055055 name: PDE6A_HUMAN def: "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha" [UniProtKB:P16499] synonym: "EC 3.1.4.35" EXACT [UniProtKB:P16499] synonym: "GMP-PDE alpha" EXACT [UniProtKB:P16499] synonym: "PDE V-B1" EXACT [UniProtKB:P16499] xref: EMBL:AAB69155.1 xref: EMBL:AAH35909.1 xref: EMBL:EAW61757.1 xref: UniProtKB:P16499 xref: UniProtKB:Q0P638 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019343 ! PDE6A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069184 ! PDE6A_HUMAN-N-acetylglycine2 [Term] id: CCO:B0055056 name: GBB3_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3" [UniProtKB:P16520] synonym: "Transducin beta chain 3" EXACT [UniProtKB:P16520] xref: EMBL:AAA52582.1 xref: EMBL:AAB51313.1 xref: EMBL:AAC50468.1 xref: EMBL:AAH00115.1 xref: EMBL:AAH02454.1 xref: EMBL:AAM15920.1 xref: EMBL:AAP88802.1 xref: EMBL:AAT38116.1 xref: EMBL:CAA72779.1 xref: UniProtKB:P16520 xref: UniProtKB:Q9BQC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017878 ! GNB3_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066391 ! GBB3_HUMAN-Phosphoserine74 [Term] id: CCO:B0055057 name: FER_HUMAN def: "Proto-oncogene tyrosine-protein kinase FER" [UniProtKB:P16591] synonym: "c-FER" EXACT [UniProtKB:P16591] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P16591] synonym: "p94-FER" EXACT [UniProtKB:P16591] synonym: "Tyrosine kinase 3" EXACT [UniProtKB:P16591] xref: EMBL:AAA61190.1 xref: UniProtKB:P16591 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017776 ! FER_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0066165 ! FER_HUMAN-Phosphotyrosine402 relationship: transforms_into CCO:B0066166 ! FER_HUMAN-Phosphoserine434 relationship: transforms_into CCO:B0066167 ! FER_HUMAN-Phosphotyrosine714 [Term] id: CCO:B0055058 name: CL3L1_HUMAN def: "C-C motif chemokine 3-like 1 precursor" [UniProtKB:P16619] synonym: "G0/G1 switch regulatory protein 19-2" EXACT [UniProtKB:P16619] synonym: "G0S19-2 protein" EXACT [UniProtKB:P16619] synonym: "LD78-beta(1-70)" EXACT [UniProtKB:P16619] synonym: "PAT 464.2" EXACT [UniProtKB:P16619] synonym: "Small-inducible cytokine A3-like 1" EXACT [UniProtKB:P16619] synonym: "Tonsillar lymphocyte LD78 beta protein" EXACT [UniProtKB:P16619] xref: EMBL:AAA35859.1 xref: EMBL:AAH07783.1 xref: EMBL:AAH27888.1 xref: EMBL:AAI07711.1 xref: EMBL:AAP35429.1 xref: EMBL:BAA14173.1 xref: EMBL:CAA36397.1 xref: UniProtKB:A6NGK6 xref: UniProtKB:P16619 xref: UniProtKB:Q3B7A8 xref: UniProtKB:Q53YA5 xref: UniProtKB:Q96I68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017372 ! CCL3L1_human relationship: encoded_by CCO:G0017373 ! CCL3L3_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055059 name: ANFB_HUMAN def: "Natriuretic peptides B precursor" [UniProtKB:P16860] synonym: "Gamma-brain natriuretic peptide" EXACT [UniProtKB:P16860] xref: EMBL:AAA35603.1 xref: EMBL:AAA36355.1 xref: EMBL:AAH25785.1 xref: EMBL:CAA15956.1 xref: EMBL:CAG46774.1 xref: EMBL:CAG46800.1 xref: UniProtKB:P16860 xref: UniProtKB:Q6FGY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016964 ! NPPB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0002011 ! diuretic hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0015301 ! ewsr1-nppb physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0055060 name: IL7RA_HUMAN def: "Interleukin-7 receptor subunit alpha precursor" [UniProtKB:P16871] synonym: "CD127 antigen" EXACT [UniProtKB:P16871] synonym: "CDw127" EXACT [UniProtKB:P16871] synonym: "IL-7R-alpha" EXACT [UniProtKB:P16871] xref: EMBL:AAA59157.1 xref: EMBL:AAC83204.1 xref: EMBL:AAH67540.1 xref: EMBL:AAR08908.1 xref: UniProtKB:P16871 xref: UniProtKB:Q6NWM0 xref: UniProtKB:Q6SV45 xref: UniProtKB:Q9UPC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018270 ! IL7R_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016221 ! il7-il7r-3 physical interaction relationship: participates_in CCO:I0017385 ! il7-il7r-2 physical interaction relationship: participates_in CCO:I0017518 ! il7-il7r-1 physical interaction relationship: participates_in CCO:P0000398 ! regulation of DNA recombination relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0067080 ! IL7RA_HUMAN-Phosphotyrosine159 relationship: transforms_into CCO:B0067081 ! IL7RA_HUMAN-Phosphotyrosine169 relationship: transforms_into CCO:B0067082 ! IL7RA_HUMAN-Phosphothreonine282 [Term] id: CCO:B0055061 name: PLCG2_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2" [UniProtKB:P16885] synonym: "EC 3.1.4.11" EXACT [UniProtKB:P16885] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:P16885] synonym: "Phospholipase C-gamma-2" EXACT [UniProtKB:P16885] synonym: "PLC-gamma-2" EXACT [UniProtKB:P16885] synonym: "PLC-IV" EXACT [UniProtKB:P16885] xref: EMBL:AAA60112.1 xref: EMBL:AAH07565.1 xref: EMBL:AAH11772.1 xref: EMBL:AAH14561.1 xref: EMBL:AAH18646.1 xref: EMBL:AAQ76815.1 xref: EMBL:BAD92151.1 xref: EMBL:CAA32194.1 xref: UniProtKB:P16885 xref: UniProtKB:Q3ZTS2 xref: UniProtKB:Q59H45 xref: UniProtKB:Q969T5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019434 ! PLCG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018194 ! epor-plcg21-3 physical interaction relationship: participates_in CCO:I0018647 ! epor-plcg21-1 physical interaction relationship: participates_in CCO:I0019254 ! epor-plcg21-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069394 ! PLCG2_HUMAN-Phosphotyrosine733 relationship: transforms_into CCO:B0069395 ! PLCG2_HUMAN-Phosphotyrosine753 relationship: transforms_into CCO:B0069396 ! PLCG2_HUMAN-Phosphotyrosine759 relationship: transforms_into CCO:B0069397 ! PLCG2_HUMAN-Phosphotyrosine1245 [Term] id: CCO:B0055062 name: ZFX_HUMAN def: "Zinc finger X-chromosomal protein" [UniProtKB:P17010] xref: EMBL:AAA61309.1 xref: EMBL:AAC03062.2 xref: EMBL:AAL62492.1 xref: EMBL:CAA42416.1 xref: EMBL:CAA42417.1 xref: EMBL:CAA42418.1 xref: UniProtKB:O43668 xref: UniProtKB:P17010 xref: UniProtKB:Q8WYJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020598 ! ZFX_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0072022 ! ZFX_HUMAN-Phosphoserine274 [Term] id: CCO:B0055063 name: ZNF12_HUMAN def: "Zinc finger protein 12" [UniProtKB:P17014] synonym: "GIOT-3" EXACT [UniProtKB:P17014] synonym: "Gonadotropin-inducible transcription repressor 3" EXACT [UniProtKB:P17014] synonym: "Zinc finger protein 325" EXACT [UniProtKB:P17014] synonym: "Zinc finger protein KOX3" EXACT [UniProtKB:P17014] xref: EMBL:BAA86989.1 xref: EMBL:CAA36560.1 xref: UniProtKB:P17014 xref: UniProtKB:Q9ULZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020958 ! ZNF12_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055064 name: ZNF14_HUMAN def: "Zinc finger protein 14" [UniProtKB:P17017] synonym: "GIOT-4" EXACT [UniProtKB:P17017] synonym: "Gonadotropin-inducible transcription repressor 4" EXACT [UniProtKB:P17017] synonym: "Zinc finger protein KOX6" EXACT [UniProtKB:P17017] xref: EMBL:BAA86990.1 xref: EMBL:CAA36563.1 xref: UniProtKB:P17017 xref: UniProtKB:Q9ULZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020959 ! ZNF14_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055065 name: ZN708_HUMAN def: "Zinc finger protein 708" [UniProtKB:P17019] synonym: "Zinc finger protein 15-like 1" EXACT [UniProtKB:P17019] synonym: "Zinc finger protein KOX8" EXACT [UniProtKB:P17019] xref: EMBL:BAD18665.1 xref: EMBL:CAA36565.1 xref: UniProtKB:P17019 xref: UniProtKB:Q6ZMR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020911 ! ZNF708_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055066 name: ZNF16_HUMAN def: "Zinc finger protein 16" [UniProtKB:P17020] synonym: "Zinc finger protein KOX9" EXACT [UniProtKB:P17020] xref: EMBL:AAH10996.2 xref: EMBL:CAA36566.1 xref: UniProtKB:P17020 xref: UniProtKB:Q96FG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020960 ! ZNF16_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055067 name: ZNF17_HUMAN def: "Zinc finger protein 17" [UniProtKB:P17021] synonym: "HPF3" EXACT [UniProtKB:P17021] synonym: "Zinc finger protein KOX10" EXACT [UniProtKB:P17021] xref: EMBL:BAB85533.1 xref: EMBL:BAC04956.1 xref: EMBL:CAA36567.1 xref: UniProtKB:P17021 xref: UniProtKB:Q8N893 xref: UniProtKB:Q8TF54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020961 ! ZNF17_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017479 ! mitap1-znf17 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055068 name: ZNF18_HUMAN def: "Zinc finger protein 18" [UniProtKB:P17022] synonym: "Heart development-specific gene 1 protein" EXACT [UniProtKB:P17022] synonym: "Zinc finger protein KOX11" EXACT [UniProtKB:P17022] synonym: "Zinc finger protein with KRAB and SCAN domains 6" EXACT [UniProtKB:P17022] xref: EMBL:AAH36096.1 xref: EMBL:AAS67595.1 xref: EMBL:BAC03939.1 xref: EMBL:CAA36568.1 xref: UniProtKB:P17022 xref: UniProtKB:Q5QHQ3 xref: UniProtKB:Q8IYC4 xref: UniProtKB:Q8NAH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020962 ! ZNF18_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055069 name: ZNF20_HUMAN def: "Zinc finger protein 20" [UniProtKB:P17024] synonym: "Zinc finger protein KOX13" EXACT [UniProtKB:P17024] xref: EMBL:CAA36570.1 xref: EMBL:CAB45723.2 xref: UniProtKB:P17024 xref: UniProtKB:Q9UG41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020963 ! ZNF20_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020218 ! znf20-hap1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055070 name: ZN182_HUMAN def: "Zinc finger protein 182" [UniProtKB:P17025] synonym: "Zinc finger protein 21" EXACT [UniProtKB:P17025] synonym: "Zinc finger protein KOX14" EXACT [UniProtKB:P17025] xref: EMBL:AAI06876.1 xref: EMBL:BAG53772.1 xref: EMBL:CAA36571.1 xref: EMBL:CAM28265.1 xref: EMBL:EAW59334.1 xref: UniProtKB:A2IDD7 xref: UniProtKB:P17025 xref: UniProtKB:Q3KP67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020643 ! ZNF182_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055071 name: ZNF22_HUMAN def: "Zinc finger protein 22" [UniProtKB:P17026] synonym: "Krox-26 protein" EXACT [UniProtKB:P17026] synonym: "Zinc finger protein KOX15" EXACT [UniProtKB:P17026] xref: EMBL:AAA36815.1 xref: EMBL:AAB24264.2 xref: EMBL:AAH10642.1 xref: EMBL:AAH41139.1 xref: EMBL:AAH53687.1 xref: EMBL:AAN15804.1 xref: EMBL:AAP88808.1 xref: EMBL:CAA36572.1 xref: UniProtKB:P17026 xref: UniProtKB:Q96FM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020964 ! ZNF22_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055072 name: ZNF23_HUMAN def: "Zinc finger protein 23" [UniProtKB:P17027] synonym: "Zinc finger protein 359" EXACT [UniProtKB:P17027] synonym: "Zinc finger protein KOX16" EXACT [UniProtKB:P17027] xref: EMBL:AAH07256.1 xref: EMBL:AAM33359.1 xref: EMBL:AAP36064.1 xref: EMBL:CAA36573.1 xref: EMBL:CAB45722.1 xref: UniProtKB:P17027 xref: UniProtKB:Q96IT3 xref: UniProtKB:Q9UG42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020965 ! ZNF23_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055073 name: ZKSC1_HUMAN def: "Zinc finger protein with KRAB and SCAN domains 1" [UniProtKB:P17029] synonym: "Zinc finger protein 36" EXACT [UniProtKB:P17029] synonym: "Zinc finger protein KOX18" EXACT [UniProtKB:P17029] xref: EMBL:AAC50264.1 xref: EMBL:AAH22378.1 xref: EMBL:AAI12225.1 xref: EMBL:AAI13698.1 xref: EMBL:BAB84942.1 xref: EMBL:CAA36575.1 xref: EMBL:CAE45792.1 xref: UniProtKB:P17029 xref: UniProtKB:P52745 xref: UniProtKB:Q2M1U1 xref: UniProtKB:Q8TBW5 xref: UniProtKB:Q8TEK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020608 ! ZKSCAN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072038 ! ZKSC1_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0072039 ! ZKSC1_HUMAN-Phosphoserine471 [Term] id: CCO:B0055074 name: ZNF25_HUMAN def: "Zinc finger protein 25" [UniProtKB:P17030] synonym: "Zinc finger protein KOX19" EXACT [UniProtKB:P17030] xref: EMBL:AAH36038.1 xref: EMBL:BAB71187.1 xref: EMBL:CAA36576.1 xref: EMBL:CAD36955.1 xref: EMBL:CAD38845.1 xref: EMBL:CAH73314.1 xref: UniProtKB:A9Z1X5 xref: UniProtKB:P17030 xref: UniProtKB:Q8IYE3 xref: UniProtKB:Q8NDD6 xref: UniProtKB:Q96MU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020966 ! ZNF25_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055075 name: ZN37A_HUMAN def: "Zinc finger protein 37A" [UniProtKB:P17032] synonym: "Zinc finger protein KOX21" EXACT [UniProtKB:P17032] xref: EMBL:AAH15858.1 xref: EMBL:CAA36578.1 xref: EMBL:CAA48868.1 xref: EMBL:CAD37331.1 xref: EMBL:CAI14947.1 xref: UniProtKB:P17032 xref: UniProtKB:Q96B88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020722 ! ZNF37A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055076 name: ZNF28_HUMAN def: "Zinc finger protein 28" [UniProtKB:P17035] synonym: "Zinc finger protein KOX24" EXACT [UniProtKB:P17035] xref: EMBL:BAD18519.1 xref: EMBL:BAD18706.1 xref: EMBL:CAA36581.1 xref: EMBL:CAI45923.1 xref: EMBL:CAI46258.1 xref: UniProtKB:P17035 xref: UniProtKB:Q5H9V1 xref: UniProtKB:Q5HYM9 xref: UniProtKB:Q6ZML9 xref: UniProtKB:Q6ZN56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020967 ! ZNF28_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055077 name: ZNF3_HUMAN def: "Zinc finger protein 3" [UniProtKB:P17036] synonym: "HZF3.1" EXACT [UniProtKB:P17036] synonym: "Zinc finger protein HF.12" EXACT [UniProtKB:P17036] synonym: "Zinc finger protein KOX25" EXACT [UniProtKB:P17036] xref: EMBL:AAH11887.2 xref: EMBL:AAH13603.1 xref: EMBL:BAA91019.1 xref: EMBL:CAA30269.1 xref: EMBL:CAA36582.1 xref: EMBL:CAB94195.1 xref: UniProtKB:P13683 xref: UniProtKB:P17036 xref: UniProtKB:Q9NNX8 xref: UniProtKB:Q9NXJ1 xref: UniProtKB:Q9UC15 xref: UniProtKB:Q9UC16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020973 ! ZNF3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055078 name: ZNF43_HUMAN def: "Zinc finger protein 43" [UniProtKB:P17038] synonym: "Zinc finger protein 39" EXACT [UniProtKB:P17038] synonym: "Zinc finger protein KOX27" EXACT [UniProtKB:P17038] synonym: "Zinc protein HTF6" EXACT [UniProtKB:P17038] xref: EMBL:AAA58674.1 xref: EMBL:AAH06528.2 xref: EMBL:CAA36584.1 xref: EMBL:CAA41932.1 xref: UniProtKB:P17038 xref: UniProtKB:P28160 xref: UniProtKB:Q96DG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020975 ! ZNF43_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055079 name: ZNF30_HUMAN def: "Zinc finger protein 30" [UniProtKB:P17039] synonym: "Zinc finger protein KOX28" EXACT [UniProtKB:P17039] xref: EMBL:BAF83124.1 xref: EMBL:CAA36585.1 xref: EMBL:CAE45802.1 xref: UniProtKB:A8K320 xref: UniProtKB:P17039 xref: UniProtKB:Q6N068 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020969 ! ZNF30_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055080 name: ZNF32_HUMAN def: "Zinc finger protein 32" [UniProtKB:P17041] synonym: "C2H2-546" EXACT [UniProtKB:P17041] synonym: "Zinc finger protein KOX30" EXACT [UniProtKB:P17041] xref: EMBL:AAB09561.1 xref: EMBL:AAH22842.1 xref: EMBL:CAA36587.1 xref: EMBL:CAH73489.1 xref: UniProtKB:P17041 xref: UniProtKB:Q92951 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020970 ! ZNF32_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055081 name: RHOQ_HUMAN def: "Rho-related GTP-binding protein RhoQ precursor" [UniProtKB:P17081] synonym: "Ras-like protein family member 7A" EXACT [UniProtKB:P17081] synonym: "Ras-related GTP-binding protein TC10" EXACT [UniProtKB:P17081] xref: EMBL:AAA36547.1 xref: EMBL:AAH56154.3 xref: EMBL:AAH65291.2 xref: EMBL:AAH70485.2 xref: EMBL:AAH93805.2 xref: EMBL:AAI01807.1 xref: EMBL:AAM21123.1 xref: EMBL:AAY14834.1 xref: UniProtKB:P17081 xref: UniProtKB:Q0VGN1 xref: UniProtKB:Q52LS8 xref: UniProtKB:Q53SJ1 xref: UniProtKB:Q6NS39 xref: UniProtKB:Q6P146 xref: UniProtKB:Q7Z480 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019735 ! RHOQ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017747 ! cdc42bpa -rhoq-1 physical interaction relationship: participates_in CCO:I0017748 ! cdc42bpg -rhoq-1 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0070014 ! RHOQ_HUMAN-Cysteine methyl ester202 [Term] id: CCO:B0055082 name: HMGA1_HUMAN def: "High mobility group protein HMG-I/HMG-Y" [UniProtKB:P17096] synonym: "High mobility group AT-hook protein 1" EXACT [UniProtKB:P17096] synonym: "High mobility group protein A1" EXACT [UniProtKB:P17096] synonym: "High mobility group protein-R" EXACT [UniProtKB:P17096] synonym: "HMG-I(Y)" EXACT [UniProtKB:P17096] xref: EMBL:AAA35998.1 xref: EMBL:AAA88072.1 xref: EMBL:AAA88073.1 xref: EMBL:AAA88074.1 xref: EMBL:AAA88075.1 xref: EMBL:AAA88076.1 xref: EMBL:AAB00145.1 xref: EMBL:AAD53889.1 xref: EMBL:AAH04924.1 xref: EMBL:AAH08832.1 xref: EMBL:AAH63434.1 xref: EMBL:AAH67083.1 xref: EMBL:AAH71864.1 xref: EMBL:CAA33080.1 xref: EMBL:CAA33081.1 xref: UniProtKB:P10910 xref: UniProtKB:P17096 xref: UniProtKB:Q9UKB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018142 ! HMGA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015285 ! ewsr1-hmga1 physical interaction relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0000651 ! loss of chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0066821 ! HMGA1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066822 ! HMGA1_HUMAN-dimethylarginine26 relationship: transforms_into CCO:B0066823 ! HMGA1_HUMAN-Omega-N-methylarginine26 relationship: transforms_into CCO:B0066824 ! HMGA1_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0066825 ! HMGA1_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0066826 ! HMGA1_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0066827 ! HMGA1_HUMAN-Phosphothreonine53 relationship: transforms_into CCO:B0066828 ! HMGA1_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0066829 ! HMGA1_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0066830 ! HMGA1_HUMAN-Phosphoserine103 [Term] id: CCO:B0055083 name: ZNF8_HUMAN def: "Zinc finger protein 8" [UniProtKB:P17098] synonym: "Zinc finger protein HF.18" EXACT [UniProtKB:P17098] xref: EMBL:AAA61314.1 xref: EMBL:AAH39323.1 xref: UniProtKB:P17098 xref: UniProtKB:Q6PI99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020992 ! ZNF8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: transforms_into CCO:B0072257 ! ZNF8_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0072258 ! ZNF8_HUMAN-Phosphoserine455 [Term] id: CCO:B0055084 name: TMM11_HUMAN def: "Transmembrane protein 11" [UniProtKB:P17152] synonym: "Protein PM1" EXACT [UniProtKB:P17152] xref: EMBL:AAH02819.1 xref: EMBL:AAH05268.1 xref: EMBL:AAH20815.1 xref: EMBL:CAA36102.1 xref: UniProtKB:P17152 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020290 ! TMEM11_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015502 ! bnip3-tmem11 physical interaction relationship: participates_in CCO:I0015663 ! bnip3l-tmem11 physical interaction relationship: participates_in CCO:I0019424 ! tmem11-bnip3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055085 name: INAR1_HUMAN def: "Interferon-alpha/beta receptor alpha chain precursor" [UniProtKB:P17181] synonym: "IFN-alpha-REC" EXACT [UniProtKB:P17181] xref: EMBL:AAA52730.1 xref: EMBL:AAH02590.1 xref: EMBL:AAH21825.1 xref: EMBL:AAT49100.1 xref: EMBL:BAD96490.1 xref: EMBL:BAD96532.1 xref: EMBL:CAA42992.1 xref: UniProtKB:P17181 xref: UniProtKB:Q53GW9 xref: UniProtKB:Q53H11 xref: UniProtKB:Q6PKD7 xref: UniProtKB:Q7M4L2 xref: UniProtKB:Q8WTZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018283 ! IFNAR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: transforms_into CCO:B0067098 ! INAR1_HUMAN-Phosphotyrosine466 relationship: transforms_into CCO:B0067099 ! INAR1_HUMAN-Phosphotyrosine481 [Term] id: CCO:B0055086 name: ANPRC_HUMAN def: "Atrial natriuretic peptide clearance receptor precursor" [UniProtKB:P17342] synonym: "ANP-C" EXACT [UniProtKB:P17342] synonym: "ANPRC" EXACT [UniProtKB:P17342] synonym: "Atrial natriuretic peptide C-type receptor" EXACT [UniProtKB:P17342] synonym: "NPR-C" EXACT [UniProtKB:P17342] xref: EMBL:AAA51734.1 xref: EMBL:AAB88801.1 xref: EMBL:CAA36523.1 xref: UniProtKB:P17342 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016976 ! NPR3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001980 ! peptide receptor activity, G-protein coupled relationship: has_function CCO:F0003479 ! natriuretic peptide receptor activity relationship: has_function CCO:F0003529 ! peptide hormone binding relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: transforms_into CCO:B0065640 ! ANPRC_HUMAN-Phosphoserine533 [Term] id: CCO:B0055087 name: ASM_HUMAN def: "Sphingomyelin phosphodiesterase precursor" [UniProtKB:P17405] synonym: "Acid sphingomyelinase" EXACT [UniProtKB:P17405] synonym: "aSMase" EXACT [UniProtKB:P17405] synonym: "EC 3.1.4.12" EXACT [UniProtKB:P17405] xref: EMBL:AAA58377.1 xref: EMBL:AAA58378.1 xref: EMBL:AAA75008.1 xref: EMBL:AAA75009.1 xref: EMBL:CAA36901.1 xref: EMBL:CAA36902.1 xref: EMBL:CAA42584.1 xref: EMBL:CAA45145.1 xref: UniProtKB:P17405 xref: UniProtKB:P17406 xref: UniProtKB:Q13811 xref: UniProtKB:Q16837 xref: UniProtKB:Q16841 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017084 ! SMPD1_human relationship: has_function CCO:F0001127 ! sphingomyelin phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055088 name: UBF1_HUMAN def: "Nucleolar transcription factor 1" [UniProtKB:P17480] synonym: "Autoantigen NOR-90" EXACT [UniProtKB:P17480] synonym: "UBF-1" EXACT [UniProtKB:P17480] synonym: "Upstream-binding factor 1" EXACT [UniProtKB:P17480] xref: EMBL:AAH42297.1 xref: EMBL:CAA37469.1 xref: EMBL:CAA37548.1 xref: EMBL:CAA40016.1 xref: UniProtKB:P17480 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020398 ! UBTF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020682 ! ubtf-chgb physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000656 ! regulation of transcription from RNA polymerase I promoter relationship: transforms_into CCO:B0071667 ! UBF1_HUMAN-Phosphoserine484 [Term] id: CCO:B0055089 name: JUND_HUMAN def: "Transcription factor jun-D" [UniProtKB:P17535] xref: EMBL:CAA35739.1 xref: EMBL:CAA40010.1 xref: UniProtKB:P17535 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018369 ! JUND_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0067230 ! JUND_HUMAN-Phosphoserine255 relationship: transforms_into CCO:B0067231 ! JUND_HUMAN-Phosphoserine259 [Term] id: CCO:B0055090 name: TAL1_HUMAN def: "T-cell acute lymphocytic leukemia protein 1" [UniProtKB:P17542] synonym: "Stem cell protein" EXACT [UniProtKB:P17542] synonym: "T-cell leukemia/lymphoma protein 5" EXACT [UniProtKB:P17542] synonym: "TAL-1" EXACT [UniProtKB:P17542] xref: EMBL:AAA36598.1 xref: EMBL:AAA36599.1 xref: EMBL:AAA36600.1 xref: EMBL:CAA36246.1 xref: EMBL:CAA41476.1 xref: EMBL:CAA41477.1 xref: EMBL:CAB72103.1 xref: UniProtKB:P17542 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020143 ! TAL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071118 ! TAL1_HUMAN-Phosphoserine122 [Term] id: CCO:B0055091 name: NEUM_HUMAN def: "Neuromodulin" [UniProtKB:P17677] synonym: "Axonal membrane protein GAP-43" EXACT [UniProtKB:P17677] synonym: "Growth-associated protein 43" EXACT [UniProtKB:P17677] synonym: "Neural phosphoprotein B-50" EXACT [UniProtKB:P17677] synonym: "PP46" EXACT [UniProtKB:P17677] xref: EMBL:AAA52516.1 xref: EMBL:AAB28649.1 xref: EMBL:AAH07936.1 xref: EMBL:AAV88094.1 xref: UniProtKB:P17677 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018759 ! GAP43_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: transforms_into CCO:B0068580 ! NEUM_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0068581 ! NEUM_HUMAN-Phosphothreonine94 relationship: transforms_into CCO:B0068582 ! NEUM_HUMAN-Phosphothreonine181 relationship: transforms_into CCO:B0068583 ! NEUM_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0068584 ! NEUM_HUMAN-Phosphoserine203 [Term] id: CCO:B0055092 name: EGLN_HUMAN def: "Endoglin precursor" [UniProtKB:P17813] synonym: "CD105 antigen" EXACT [UniProtKB:P17813] xref: EMBL:AAA35800.1 xref: EMBL:AAC63386.1 xref: EMBL:CAA50891.1 xref: UniProtKB:P17813 xref: UniProtKB:Q14248 xref: UniProtKB:Q14926 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017664 ! ENG_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001274 ! positive regulation of BMP signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055093 name: XBP1_HUMAN def: "X-box-binding protein 1" [UniProtKB:P17861] synonym: "Tax-responsive element-binding protein 5" EXACT [UniProtKB:P17861] synonym: "XBP-1" EXACT [UniProtKB:P17861] xref: EMBL:AAA36031.1 xref: EMBL:AAH00938.1 xref: EMBL:AAH12841.1 xref: EMBL:AAH15709.1 xref: EMBL:BAB82981.1 xref: EMBL:BAB82982.1 xref: EMBL:CAA39149.1 xref: EMBL:CAB45016.1 xref: EMBL:CAG30497.1 xref: UniProtKB:P17861 xref: UniProtKB:Q8WYK6 xref: UniProtKB:Q969P1 xref: UniProtKB:Q96BD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020505 ! XBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055094 name: IBP3_HUMAN def: "Insulin-like growth factor-binding protein 3 precursor" [UniProtKB:P17936] synonym: "IBP-3" EXACT [UniProtKB:P17936] synonym: "IGF-binding protein 3" EXACT [UniProtKB:P17936] synonym: "IGFBP-3" EXACT [UniProtKB:P17936] xref: EMBL:AAA52541.1 xref: EMBL:AAA52706.1 xref: EMBL:AAH00013.1 xref: EMBL:AAH18962.1 xref: EMBL:AAH64987.1 xref: EMBL:AAS07554.1 xref: EMBL:ABB96247.1 xref: EMBL:CAA46087.1 xref: UniProtKB:P17936 xref: UniProtKB:Q2V509 xref: UniProtKB:Q6P1M6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018209 ! IGFBP3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001754 ! protein tyrosine phosphatase activator activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004919 ! insulin-like growth factor I binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000829 ! insulin-like growth factor binding protein complex relationship: participates_in CCO:I0020039 ! igfbp3-gtf3c1 physical interaction relationship: participates_in CCO:I0020339 ! igfbp3-pola2 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000501 ! negative regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0001109 ! negative regulation of smooth muscle cell migration relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002477 ! positive regulation of myoblast differentiation relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation [Term] id: CCO:B0055095 name: SPI1_HUMAN def: "Transcription factor PU.1" [UniProtKB:P17947] synonym: "31 kDa-transforming protein" EXACT [UniProtKB:P17947] xref: EMBL:CAA36281.1 xref: UniProtKB:P17947 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020014 ! SPI1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002460 ! regulation of erythrocyte differentiation [Term] id: CCO:B0055096 name: PTN1_HUMAN def: "Tyrosine-protein phosphatase non-receptor type 1" [UniProtKB:P18031] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P18031] synonym: "Protein-tyrosine phosphatase 1B" EXACT [UniProtKB:P18031] synonym: "PTP-1B" EXACT [UniProtKB:P18031] xref: EMBL:AAA60157.1 xref: EMBL:AAA60158.1 xref: EMBL:AAA60223.1 xref: EMBL:AAH15660.1 xref: EMBL:AAH18164.1 xref: EMBL:AAP35398.1 xref: EMBL:CAC00618.2 xref: EMBL:CAI23215.1 xref: UniProtKB:P18031 xref: UniProtKB:Q5TGD8 xref: UniProtKB:Q9BQV9 xref: UniProtKB:Q9NQQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019547 ! PTPN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018875 ! ptpn1-actn1-1 dephosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0069595 ! PTN1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0069596 ! PTN1_HUMAN-Phosphotyrosine20 relationship: transforms_into CCO:B0069597 ! PTN1_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0069598 ! PTN1_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0069599 ! PTN1_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0069600 ! PTN1_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0069601 ! PTN1_HUMAN-Phosphoserine386 relationship: transforms_into CCO:B0069602 ! PTN1_HUMAN-Phosphoserine393 [Term] id: CCO:B0055097 name: LOX12_HUMAN def: "Arachidonate 12-lipoxygenase, 12S-type" [UniProtKB:P18054] synonym: "12-LOX" EXACT [UniProtKB:P18054] synonym: "EC 1.13.11.31" EXACT [UniProtKB:P18054] synonym: "Platelet-type lipoxygenase 12" EXACT [UniProtKB:P18054] xref: EMBL:AAA51533.1 xref: EMBL:AAA51587.1 xref: EMBL:AAA59523.1 xref: EMBL:AAA60056.1 xref: EMBL:AAD14020.1 xref: EMBL:AAD32700.1 xref: EMBL:AAH69557.1 xref: EMBL:AAS00094.1 xref: EMBL:BAA02162.1 xref: UniProtKB:O95569 xref: UniProtKB:P18054 xref: UniProtKB:Q6ISF8 xref: UniProtKB:Q9UQM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018515 ! ALOX12_human relationship: has_function CCO:F0000527 ! arachidonate 12-lipoxygenase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003056 ! lipoxygenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007276 ! hepoxilin-epoxide hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001638 ! sarcolemma relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001254 ! positive regulation of cell growth relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion [Term] id: CCO:B0055098 name: IBP2_HUMAN def: "Insulin-like growth factor-binding protein 2 precursor" [UniProtKB:P18065] synonym: "IBP-2" EXACT [UniProtKB:P18065] synonym: "IGF-binding protein 2" EXACT [UniProtKB:P18065] synonym: "IGFBP-2" EXACT [UniProtKB:P18065] xref: EMBL:AAA03246.1 xref: EMBL:AAA36048.1 xref: EMBL:AAB22308.1 xref: EMBL:AAH04312.1 xref: EMBL:AAH09902.1 xref: EMBL:AAH12769.1 xref: EMBL:AAH71967.1 xref: EMBL:AAQ87876.1 xref: EMBL:CAA00862.1 xref: EMBL:CAA34373.1 xref: UniProtKB:P18065 xref: UniProtKB:Q14619 xref: UniProtKB:Q9UCL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018208 ! IGFBP2_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004919 ! insulin-like growth factor I binding relationship: has_function CCO:F0004920 ! insulin-like growth factor II binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055099 name: ARF4_HUMAN def: "ADP-ribosylation factor 4" [UniProtKB:P18085] xref: EMBL:AAA53081.1 xref: EMBL:AAD54674.1 xref: EMBL:AAH03364.1 xref: EMBL:AAH08753.1 xref: EMBL:AAH16325.1 xref: EMBL:AAH22866.1 xref: EMBL:AAM12597.1 xref: UniProtKB:P18085 xref: UniProtKB:P21371 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017005 ! ARF4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055100 name: EGR1_HUMAN def: "Early growth response protein 1" [UniProtKB:P18146] synonym: "AT225" EXACT [UniProtKB:P18146] synonym: "EGR-1" EXACT [UniProtKB:P18146] synonym: "Nerve growth factor-induced protein A" EXACT [UniProtKB:P18146] synonym: "NGFI-A" EXACT [UniProtKB:P18146] synonym: "Protein Krox-24" EXACT [UniProtKB:P18146] synonym: "Transcription factor ETR103" EXACT [UniProtKB:P18146] synonym: "Transcription factor Zif268" EXACT [UniProtKB:P18146] synonym: "Zinc finger protein 225" EXACT [UniProtKB:P18146] xref: EMBL:AAA35815.1 xref: EMBL:AAH73983.1 xref: EMBL:CAA36777.1 xref: UniProtKB:P18146 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017665 ! EGR1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055101 name: SON_HUMAN def: "SON protein" [UniProtKB:P18583] synonym: "BASS1" EXACT [UniProtKB:P18583] synonym: "Bax antagonist selected in saccharomyces 1" EXACT [UniProtKB:P18583] synonym: "DBP-5" EXACT [UniProtKB:P18583] synonym: "Negative regulatory element-binding protein" EXACT [UniProtKB:P18583] synonym: "NRE-binding protein" EXACT [UniProtKB:P18583] synonym: "SON3" EXACT [UniProtKB:P18583] xref: EMBL:AAA36624.1 xref: EMBL:AAD50078.1 xref: EMBL:AAF28988.1 xref: EMBL:AAF28990.1 xref: EMBL:AAK07692.1 xref: EMBL:AAL30810.1 xref: EMBL:AAL34497.1 xref: EMBL:AAL34498.1 xref: EMBL:AAL34499.1 xref: EMBL:AAL34500.1 xref: EMBL:AAL34501.1 xref: EMBL:AAL34502.1 xref: EMBL:BAA82971.2 xref: EMBL:BAB14985.1 xref: EMBL:CAA44793.1 xref: EMBL:CAA45282.1 xref: EMBL:CAC69885.1 xref: UniProtKB:O14487 xref: UniProtKB:O95981 xref: UniProtKB:P18583 xref: UniProtKB:Q14120 xref: UniProtKB:Q9H7B1 xref: UniProtKB:Q9P070 xref: UniProtKB:Q9P072 xref: UniProtKB:Q9UKP9 xref: UniProtKB:Q9UPY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019982 ! SON_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0070725 ! SON_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0070726 ! SON_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0070727 ! SON_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0070728 ! SON_HUMAN-Phosphoserine910 relationship: transforms_into CCO:B0070729 ! SON_HUMAN-Phosphoserine1651 relationship: transforms_into CCO:B0070730 ! SON_HUMAN-Phosphoserine1688 relationship: transforms_into CCO:B0070731 ! SON_HUMAN-Phosphoserine1697 relationship: transforms_into CCO:B0070732 ! SON_HUMAN-Phosphoserine1766 relationship: transforms_into CCO:B0070733 ! SON_HUMAN-Phosphoserine1769 relationship: transforms_into CCO:B0070734 ! SON_HUMAN-Phosphoserine1784 relationship: transforms_into CCO:B0070735 ! SON_HUMAN-Phosphoserine1948 relationship: transforms_into CCO:B0070736 ! SON_HUMAN-Phosphoserine1950 relationship: transforms_into CCO:B0070737 ! SON_HUMAN-Phosphoserine1961 relationship: transforms_into CCO:B0070738 ! SON_HUMAN-Phosphoserine2009 relationship: transforms_into CCO:B0070739 ! SON_HUMAN-Phosphoserine2011 relationship: transforms_into CCO:B0070740 ! SON_HUMAN-Phosphoserine2013 relationship: transforms_into CCO:B0070741 ! SON_HUMAN-Phosphoserine2029 relationship: transforms_into CCO:B0070742 ! SON_HUMAN-Phosphoserine2031 relationship: transforms_into CCO:B0070743 ! SON_HUMAN-N6-acetyllysine2055 relationship: transforms_into CCO:B0070744 ! SON_HUMAN-Phosphoserine2129 [Term] id: CCO:B0055102 name: NELFE_HUMAN def: "Negative elongation factor E" [UniProtKB:P18615] synonym: "NELF-E" EXACT [UniProtKB:P18615] synonym: "RNA-binding protein RD" EXACT [UniProtKB:P18615] xref: EMBL:AAA36308.1 xref: EMBL:AAB67979.1 xref: EMBL:AAC37523.1 xref: EMBL:AAH25235.1 xref: EMBL:AAH50617.1 xref: EMBL:CAA34231.1 xref: EMBL:CAB89308.1 xref: EMBL:CAI17457.1 xref: EMBL:CAI41861.1 xref: UniProtKB:P18615 xref: UniProtKB:Q5JP74 xref: UniProtKB:Q5JP75 xref: UniProtKB:Q96F56 xref: UniProtKB:Q9NPK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018752 ! RDBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018448 ! rdbp-nelfb physical interaction relationship: participates_in CCO:I0018449 ! rdbp-ncor1 physical interaction relationship: participates_in CCO:I0020432 ! rdbp-vamp3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068567 ! NELFE_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0068568 ! NELFE_HUMAN-Phosphoserine115 relationship: transforms_into CCO:B0068569 ! NELFE_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0068570 ! NELFE_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0068571 ! NELFE_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0068572 ! NELFE_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0068573 ! NELFE_HUMAN-Phosphoserine353 [Term] id: CCO:B0055103 name: LAG3_HUMAN def: "Lymphocyte activation gene 3 protein precursor" [UniProtKB:P18627] synonym: "CD223 antigen" EXACT [UniProtKB:P18627] synonym: "FDC protein" EXACT [UniProtKB:P18627] synonym: "LAG-3" EXACT [UniProtKB:P18627] xref: EMBL:CAA36243.3 xref: UniProtKB:P18627 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018450 ! LAG3_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0005649 ! MHC class II protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002277 ! negative regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002637 ! positive regulation of natural killer cell mediated cytotoxicity relationship: participates_in CCO:P0002986 ! negative regulation of T cell activation [Term] id: CCO:B0055104 name: ADA2C_HUMAN def: "Alpha-2C adrenergic receptor" [UniProtKB:P18825] synonym: "Alpha-2 adrenergic receptor subtype C4" EXACT [UniProtKB:P18825] synonym: "Alpha-2C adrenoceptor" EXACT [UniProtKB:P18825] synonym: "Alpha-2C adrenoreceptor" EXACT [UniProtKB:P18825] xref: EMBL:AAA35513.1 xref: EMBL:AAC78723.1 xref: EMBL:AAG28076.1 xref: EMBL:AAG28077.1 xref: EMBL:AAR18071.1 xref: EMBL:AAT02221.1 xref: EMBL:BAA02737.1 xref: UniProtKB:P18825 xref: UniProtKB:P35369 xref: UniProtKB:Q9HB49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016908 ! ADRA2C_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001280 ! alpha2-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055105 name: ATF1_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-1" [UniProtKB:P18846] synonym: "Activating transcription factor 1" EXACT [UniProtKB:P18846] synonym: "TREB36 protein" EXACT [UniProtKB:P18846] xref: EMBL:AAH29619.1 xref: EMBL:CAA39150.1 xref: UniProtKB:P18846 xref: UniProtKB:P25168 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017093 ! ATF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063650 ! ATF1_HUMAN-Phosphoserine63 [Term] id: CCO:B0055106 name: EPOR_HUMAN def: "Erythropoietin receptor precursor" [UniProtKB:P19235] synonym: "EPO-R" EXACT [UniProtKB:P19235] xref: EMBL:AAA52392.1 xref: EMBL:AAA52393.1 xref: EMBL:AAA52401.1 xref: EMBL:AAA52403.1 xref: EMBL:AAB23271.1 xref: EMBL:AAI12154.1 xref: EMBL:CAA40550.1 xref: UniProtKB:P19235 xref: UniProtKB:Q15443 xref: UniProtKB:Q2M205 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017721 ! EPOR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015942 ! epor-socs2-4 physical interaction relationship: participates_in CCO:I0017745 ! epor-socs2-3 physical interaction relationship: participates_in CCO:I0018194 ! epor-plcg21-3 physical interaction relationship: participates_in CCO:I0018504 ! epor-socs2-5 physical interaction relationship: participates_in CCO:I0018505 ! epor-cish-6 physical interaction relationship: participates_in CCO:I0018647 ! epor-plcg21-1 physical interaction relationship: participates_in CCO:I0018740 ! epo-epor-1 direct interaction relationship: participates_in CCO:I0018741 ! epo-epor-2 direct interaction relationship: participates_in CCO:I0019254 ! epor-plcg21-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065091 ! EPOR_HUMAN-Phosphotyrosine368 relationship: transforms_into CCO:B0065092 ! EPOR_HUMAN-Phosphotyrosine426 relationship: transforms_into CCO:B0065093 ! EPOR_HUMAN-Phosphotyrosine454 relationship: transforms_into CCO:B0065094 ! EPOR_HUMAN-Phosphotyrosine456 relationship: transforms_into CCO:B0065095 ! EPOR_HUMAN-Phosphotyrosine468 relationship: transforms_into CCO:B0065096 ! EPOR_HUMAN-Phosphotyrosine485 relationship: transforms_into CCO:B0065097 ! EPOR_HUMAN-Phosphotyrosine489 relationship: transforms_into CCO:B0065098 ! EPOR_HUMAN-Phosphotyrosine504 [Term] id: CCO:B0055107 name: VCAM1_HUMAN def: "Vascular cell adhesion protein 1 precursor" [UniProtKB:P19320] synonym: "CD106 antigen" EXACT [UniProtKB:P19320] synonym: "INCAM-100" EXACT [UniProtKB:P19320] synonym: "V-CAM 1" EXACT [UniProtKB:P19320] xref: EMBL:AAA51917.1 xref: EMBL:AAA61269.1 xref: EMBL:AAA61270.1 xref: EMBL:AAH17276.3 xref: EMBL:AAH68490.2 xref: EMBL:AAH85003.1 xref: EMBL:AAM96190.1 xref: EMBL:CAA37218.1 xref: UniProtKB:P19320 xref: UniProtKB:Q6NUP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020439 ! VCAM1_human relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation [Term] id: CCO:B0055108 name: CD53_HUMAN def: "Leukocyte surface antigen CD53" [UniProtKB:P19397] synonym: "CD53 antigen" EXACT [UniProtKB:P19397] synonym: "Cell surface glycoprotein CD53" EXACT [UniProtKB:P19397] synonym: "Tetraspanin-25" EXACT [UniProtKB:P19397] synonym: "Tspan-25" EXACT [UniProtKB:P19397] xref: EMBL:AAA35663.1 xref: EMBL:AAA51951.1 xref: EMBL:AAH40693.1 xref: EMBL:AAV38449.1 xref: EMBL:CAH73292.1 xref: UniProtKB:P19397 xref: UniProtKB:Q5U0D6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017304 ! CD53_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055109 name: HME2_HUMAN def: "Homeobox protein engrailed-2" [UniProtKB:P19622] synonym: "Hu-En-2" EXACT [UniProtKB:P19622] xref: EMBL:AAA53504.2 xref: EMBL:AAF68670.1 xref: EMBL:AAI04971.1 xref: EMBL:AAI04973.1 xref: EMBL:AAQ96875.1 xref: UniProtKB:P19622 xref: UniProtKB:Q549U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018141 ! EN2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055110 name: NFKB1_HUMAN def: "Nuclear factor NF-kappa-B p105 subunit" [UniProtKB:P19838] synonym: "DNA-binding factor KBF1" EXACT [UniProtKB:P19838] synonym: "EBP-1" EXACT [UniProtKB:P19838] xref: EMBL:AAA36360.1 xref: EMBL:AAA36361.1 xref: EMBL:AAF35232.1 xref: EMBL:AAH33210.1 xref: EMBL:AAH51765.1 xref: EMBL:AAO30127.1 xref: EMBL:CAB94757.1 xref: EMBL:CAH18336.1 xref: UniProtKB:P19838 xref: UniProtKB:Q68D84 xref: UniProtKB:Q86V43 xref: UniProtKB:Q8N4X7 xref: UniProtKB:Q9NZC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018779 ! NFKB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016014 ! nfkb1-pdcd11-2 physical interaction relationship: participates_in CCO:I0016142 ! hdac1-nfkb1-7 direct interaction relationship: participates_in CCO:I0016144 ! hdac1-nfkb1-8 direct interaction relationship: participates_in CCO:I0016358 ! rel-nfkb1 physical interaction relationship: participates_in CCO:I0016377 ! nfkbia-nfkb1 physical interaction relationship: participates_in CCO:I0016425 ! nfkbie-nfkb1 physical interaction relationship: participates_in CCO:I0017154 ! map3k8-nfkb1 physical interaction relationship: participates_in CCO:I0017174 ! nfkbib-nfkb1 physical interaction relationship: participates_in CCO:I0017197 ! nfkb2-nfkb1-1 physical interaction relationship: participates_in CCO:I0017248 ! relb-nfkb1 physical interaction relationship: participates_in CCO:I0017787 ! nfkb1-nfkbia-1 physical interaction relationship: participates_in CCO:I0017841 ! nfkb1-pdcd11-1 physical interaction relationship: participates_in CCO:I0018869 ! hdac1-nfkb1 physical interaction relationship: participates_in CCO:I0018870 ! hdac1-nfkb1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0068661 ! NFKB1_HUMAN-S-nitrosocysteine61 relationship: transforms_into CCO:B0068662 ! NFKB1_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0068663 ! NFKB1_HUMAN-N6-acetyllysine431 relationship: transforms_into CCO:B0068664 ! NFKB1_HUMAN-N6-acetyllysine440 relationship: transforms_into CCO:B0068665 ! NFKB1_HUMAN-N6-acetyllysine441 relationship: transforms_into CCO:B0068666 ! NFKB1_HUMAN-Phosphoserine903 relationship: transforms_into CCO:B0068667 ! NFKB1_HUMAN-Phosphoserine907 relationship: transforms_into CCO:B0068668 ! NFKB1_HUMAN-Phosphoserine927 relationship: transforms_into CCO:B0068669 ! NFKB1_HUMAN-Phosphoserine932 [Term] id: CCO:B0055111 name: FST_HUMAN def: "Follistatin precursor" [UniProtKB:P19883] synonym: "Activin-binding protein" EXACT [UniProtKB:P19883] synonym: "FS" EXACT [UniProtKB:P19883] xref: EMBL:AAA35851.1 xref: EMBL:AAH04107.1 xref: UniProtKB:P19883 xref: UniProtKB:Q9BTH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017843 ! FST_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003570 ! activin inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002743 ! negative regulation of follicle-stimulating hormone secretion [Term] id: CCO:B0055112 name: TYPH_HUMAN def: "Thymidine phosphorylase precursor" [UniProtKB:P19971] synonym: "EC 2.4.2.4" EXACT [UniProtKB:P19971] synonym: "Gliostatin" EXACT [UniProtKB:P19971] synonym: "PD-ECGF" EXACT [UniProtKB:P19971] synonym: "Platelet-derived endothelial cell growth factor" EXACT [UniProtKB:P19971] synonym: "TdRPase" EXACT [UniProtKB:P19971] synonym: "TP" EXACT [UniProtKB:P19971] xref: EMBL:AAA60043.1 xref: EMBL:AAB03344.2 xref: EMBL:AAH18160.1 xref: EMBL:AAH52211.1 xref: UniProtKB:A8MW15 xref: UniProtKB:P19971 xref: UniProtKB:Q13390 xref: UniProtKB:Q8WVB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020395 ! TYMP_human relationship: has_function CCO:F0001463 ! platelet-derived growth factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0002361 ! thymidine phosphorylase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0003338 ! transferase activity, transferring pentosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0055113 name: CD33_HUMAN def: "Myeloid cell surface antigen CD33 precursor" [UniProtKB:P20138] synonym: "CD33 antigen" EXACT [UniProtKB:P20138] synonym: "gp67" EXACT [UniProtKB:P20138] synonym: "Sialic acid-binding Ig-like lectin 3" EXACT [UniProtKB:P20138] synonym: "Siglec-3" EXACT [UniProtKB:P20138] xref: EMBL:AAA51948.1 xref: EMBL:AAH28152.1 xref: EMBL:AAK83654.1 xref: UniProtKB:P20138 xref: UniProtKB:Q8TD24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017297 ! CD33_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0064151 ! CD33_HUMAN-Phosphotyrosine340 relationship: transforms_into CCO:B0064152 ! CD33_HUMAN-Phosphotyrosine358 [Term] id: CCO:B0055114 name: CAP7_HUMAN def: "Azurocidin precursor" [UniProtKB:P20160] synonym: "Cationic antimicrobial protein CAP37" EXACT [UniProtKB:P20160] synonym: "HBP" EXACT [UniProtKB:P20160] synonym: "Heparin-binding protein" EXACT [UniProtKB:P20160] xref: EMBL:AAB59353.1 xref: EMBL:AAH69495.1 xref: EMBL:AAH93931.1 xref: EMBL:AAH93933.1 xref: EMBL:CAA41601.1 xref: UniProtKB:P20160 xref: UniProtKB:P80014 xref: UniProtKB:Q52LG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017224 ! AZU1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0002995 ! toxin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001655 ! azurophil granule relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0002099 ! positive regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion relationship: participates_in CCO:P0002932 ! positive regulation of interleukin-1 beta biosynthetic process relationship: participates_in CCO:P0002941 ! positive regulation of fractalkine biosynthetic process relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis [Term] id: CCO:B0055115 name: ACM3_HUMAN def: "Muscarinic acetylcholine receptor M3" [UniProtKB:P20309] xref: EMBL:AAA70337.1 xref: EMBL:AAG30036.1 xref: EMBL:AAH96844.1 xref: EMBL:AAI21027.1 xref: EMBL:AAM18940.1 xref: EMBL:BAA94480.1 xref: EMBL:CAA33337.1 xref: EMBL:CAH72987.1 xref: UniProtKB:P20309 xref: UniProtKB:Q0VAJ8 xref: UniProtKB:Q4QRI3 xref: UniProtKB:Q5VXY2 xref: UniProtKB:Q9HB60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016900 ! CHRM3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001319 ! muscarinic acetylcholine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055116 name: RAB3A_HUMAN def: "Ras-related protein Rab-3A" [UniProtKB:P20336] xref: EMBL:AAA60242.1 xref: EMBL:AAD46811.1 xref: EMBL:AAF67385.1 xref: EMBL:AAF67748.1 xref: EMBL:AAH11782.1 xref: EMBL:AAM21079.1 xref: UniProtKB:P20336 xref: UniProtKB:Q9NYE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019593 ! RAB3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069679 ! RAB3A_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0069680 ! RAB3A_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0069681 ! RAB3A_HUMAN-Cysteine methyl ester220 [Term] id: CCO:B0055117 name: RAB3B_HUMAN def: "Ras-related protein Rab-3B" [UniProtKB:P20337] xref: EMBL:AAA60243.1 xref: EMBL:AAH05035.1 xref: EMBL:AAM21080.1 xref: EMBL:CAH74098.1 xref: EMBL:CAI17027.1 xref: UniProtKB:P20337 xref: UniProtKB:Q5VUL2 xref: UniProtKB:Q9BSI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019594 ! RAB3B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069682 ! RAB3B_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0069683 ! RAB3B_HUMAN-Cysteine methyl ester219 [Term] id: CCO:B0055118 name: RAB6A_HUMAN def: "Ras-related protein Rab-6A" [UniProtKB:P20340] synonym: "Rab-6" EXACT [UniProtKB:P20340] xref: EMBL:AAA60246.1 xref: EMBL:AAD25535.1 xref: EMBL:AAD27707.1 xref: EMBL:AAF23593.1 xref: EMBL:AAF73841.1 xref: EMBL:AAH03617.1 xref: EMBL:AAH68486.1 xref: EMBL:AAH96818.1 xref: EMBL:AAM21087.1 xref: EMBL:AAM21089.1 xref: EMBL:AAV38504.1 xref: EMBL:BAB71371.1 xref: UniProtKB:P20340 xref: UniProtKB:Q5U0A8 xref: UniProtKB:Q9UBE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019602 ! RAB6A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015282 ! pmm1-rab6a physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069690 ! RAB6A_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0069691 ! RAB6A_HUMAN-Phosphothreonine180 relationship: transforms_into CCO:B0069692 ! RAB6A_HUMAN-Cysteine methyl ester208 [Term] id: CCO:B0055119 name: TKN1_HUMAN def: "Protachykinin-1 precursor" [UniProtKB:P20366] synonym: "PPT" EXACT [UniProtKB:P20366] xref: EMBL:AAA60159.1 xref: EMBL:AAA60160.1 xref: EMBL:AAA79195.1 xref: EMBL:AAC15701.1 xref: EMBL:AAC15702.1 xref: EMBL:AAC15704.1 xref: EMBL:AAH18047.1 xref: EMBL:BAD96677.1 xref: EMBL:CAA38351.1 xref: UniProtKB:O60600 xref: UniProtKB:O60601 xref: UniProtKB:P20366 xref: UniProtKB:Q00072 xref: UniProtKB:Q53GH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020278 ! TAC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0020180 ! tac1-bat3 physical interaction relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0071409 ! TKN1_HUMAN-Methionine amide68 relationship: transforms_into CCO:B0071410 ! TKN1_HUMAN-Methionine amide107 [Term] id: CCO:B0055120 name: MCH_HUMAN def: "Pro-MCH precursor" [UniProtKB:P20382] xref: EMBL:AAA63214.1 xref: EMBL:AAB27493.1 xref: UniProtKB:P20382 xref: UniProtKB:Q16044 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018589 ! PMCH_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0004408 ! melanin-concentrating hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0068056 ! MCH_HUMAN-Isoleucine amide143 [Term] id: CCO:B0055121 name: NR1D1_HUMAN def: "Nuclear receptor subfamily 1 group D member 1" [UniProtKB:P20393] synonym: "Rev-erbA-alpha" EXACT [UniProtKB:P20393] synonym: "V-erbA-related protein EAR-1" EXACT [UniProtKB:P20393] xref: EMBL:AAA36561.1 xref: EMBL:AAA36562.2 xref: EMBL:AAA52332.1 xref: EMBL:AAA52335.1 xref: EMBL:AAH47875.1 xref: EMBL:AAH56148.1 xref: EMBL:CAB53540.1 xref: UniProtKB:P20393 xref: UniProtKB:Q0P5Z4 xref: UniProtKB:Q15304 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018849 ! NR1D1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068817 ! NR1D1_HUMAN-Phosphoserine23 [Term] id: CCO:B0055122 name: TRH_HUMAN def: "Prothyroliberin precursor" [UniProtKB:P20396] xref: EMBL:AAA36480.1 xref: EMBL:AAH69375.1 xref: EMBL:AAH74888.1 xref: EMBL:AAH74889.1 xref: EMBL:AAI10516.1 xref: EMBL:AAI10517.1 xref: UniProtKB:P20396 xref: UniProtKB:Q2TB83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020353 ! TRH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0071538 ! TRH_HUMAN-Pyrrolidone carboxylic acid84 relationship: transforms_into CCO:B0071539 ! TRH_HUMAN-Proline amide86 relationship: transforms_into CCO:B0071540 ! TRH_HUMAN-Pyrrolidone carboxylic acid114 relationship: transforms_into CCO:B0071541 ! TRH_HUMAN-Proline amide116 relationship: transforms_into CCO:B0071542 ! TRH_HUMAN-Pyrrolidone carboxylic acid135 relationship: transforms_into CCO:B0071543 ! TRH_HUMAN-Proline amide137 relationship: transforms_into CCO:B0071544 ! TRH_HUMAN-Pyrrolidone carboxylic acid152 relationship: transforms_into CCO:B0071545 ! TRH_HUMAN-Proline amide154 relationship: transforms_into CCO:B0071546 ! TRH_HUMAN-Pyrrolidone carboxylic acid186 relationship: transforms_into CCO:B0071547 ! TRH_HUMAN-Proline amide188 relationship: transforms_into CCO:B0071548 ! TRH_HUMAN-Pyrrolidone carboxylic acid227 relationship: transforms_into CCO:B0071549 ! TRH_HUMAN-Proline amide229 [Term] id: CCO:B0055123 name: MX1_HUMAN def: "Interferon-induced GTP-binding protein Mx1" [UniProtKB:P20591] synonym: "IFI-78K" EXACT [UniProtKB:P20591] synonym: "Interferon-induced protein p78" EXACT [UniProtKB:P20591] synonym: "Interferon-regulated resistance GTP-binding protein MxA" EXACT [UniProtKB:P20591] synonym: "Myxovirus resistance protein 1" EXACT [UniProtKB:P20591] xref: EMBL:AAA36337.1 xref: EMBL:AAA36458.1 xref: EMBL:AAD43063.1 xref: EMBL:AAH32602.1 xref: EMBL:CAB90556.1 xref: UniProtKB:P20591 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018685 ! MX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015971 ! mx1-trpc6-1 physical interaction relationship: participates_in CCO:I0017400 ! mx1-trpc6-4 physical interaction relationship: participates_in CCO:I0017401 ! mx1-trpc1-1 physical interaction relationship: participates_in CCO:I0017402 ! mx1-trpc3-2 physical interaction relationship: participates_in CCO:I0017403 ! mx1-trpc4-2 physical interaction relationship: participates_in CCO:I0017915 ! mx1-trpc6-2 physical interaction relationship: participates_in CCO:I0019449 ! mx1-trpc6-3 physical interaction relationship: participates_in CCO:I0019450 ! mx1-trpc3-1 physical interaction relationship: participates_in CCO:I0019451 ! mx1-trpc4-1 physical interaction relationship: participates_in CCO:I0019452 ! mx1-trpc5-1 physical interaction relationship: participates_in CCO:I0019453 ! mx1-trpc7-7 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068327 ! MX1_HUMAN-Phosphotyrosine129 relationship: transforms_into CCO:B0068328 ! MX1_HUMAN-Phosphotyrosine451 [Term] id: CCO:B0055124 name: NTF3_HUMAN def: "Neurotrophin-3 precursor" [UniProtKB:P20783] synonym: "HDNF" EXACT [UniProtKB:P20783] synonym: "Nerve growth factor 2" EXACT [UniProtKB:P20783] synonym: "Neurotrophic factor" EXACT [UniProtKB:P20783] synonym: "NGF-2" EXACT [UniProtKB:P20783] synonym: "NT-3" EXACT [UniProtKB:P20783] xref: EMBL:AAA59953.1 xref: EMBL:AAA63231.1 xref: EMBL:AAH69773.1 xref: EMBL:AAI07076.1 xref: EMBL:CAA37703.1 xref: EMBL:CAG46704.1 xref: EMBL:EAW88824.1 xref: UniProtKB:P20783 xref: UniProtKB:Q6FH50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018881 ! NTF3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0007336 ! nerve growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0017264 ! bdnf-ntf3-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002495 ! positive regulation of glial cell differentiation relationship: participates_in CCO:P0002958 ! regulation of synaptic transmission [Term] id: CCO:B0055125 name: EDN2_HUMAN def: "Endothelin-2 precursor" [UniProtKB:P20800] synonym: "ET-2" EXACT [UniProtKB:P20800] synonym: "PPET2" EXACT [UniProtKB:P20800] synonym: "Preproendothelin-2" EXACT [UniProtKB:P20800] xref: EMBL:AAA52340.1 xref: EMBL:AAA52404.1 xref: EMBL:AAH34393.1 xref: EMBL:AAR89914.1 xref: EMBL:CAA38962.1 xref: UniProtKB:P20800 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017659 ! EDN2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0055126 name: IL11_HUMAN def: "Interleukin-11 precursor" [UniProtKB:P20809] synonym: "Adipogenesis inhibitory factor" EXACT [UniProtKB:P20809] synonym: "AGIF" EXACT [UniProtKB:P20809] synonym: "IL-11" EXACT [UniProtKB:P20809] synonym: "Oprelvekin" EXACT [UniProtKB:P20809] xref: EMBL:AAA59132.1 xref: EMBL:AAH12506.1 xref: EMBL:AAO13493.1 xref: EMBL:CAA41266.1 xref: UniProtKB:P20809 xref: UniProtKB:Q96EB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018248 ! IL11_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001444 ! interleukin-11 receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001795 ! positive regulation of peptidyl-serine phosphorylation relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002748 ! negative regulation of hormone secretion relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0055127 name: NEBU_HUMAN def: "Nebulin" [UniProtKB:P20929] xref: EMBL:AAA59917.1 xref: EMBL:AAY14651.1 xref: EMBL:AAY14977.1 xref: EMBL:CAA58788.1 xref: UniProtKB:P20929 xref: UniProtKB:Q15346 xref: UniProtKB:Q53QQ2 xref: UniProtKB:Q53TG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018747 ! NEB_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000934 ! Z disc relationship: participates_in CCO:P0001325 ! regulation of actin filament length [Term] id: CCO:B0055128 name: YYY3_HUMAN xref: UniProtKB:P20931 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001702 ! growth factor activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055129 name: PHOS_HUMAN def: "Phosducin" [UniProtKB:P20941] synonym: "33 kDa phototransducing protein" EXACT [UniProtKB:P20941] synonym: "MEKA protein" EXACT [UniProtKB:P20941] synonym: "PHD" EXACT [UniProtKB:P20941] xref: EMBL:AAA35486.1 xref: EMBL:AAA36210.1 xref: EMBL:CAI13122.1 xref: UniProtKB:P20941 xref: UniProtKB:Q14816 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019384 ! PDC_human relationship: has_function CCO:F0001215 ! phospholipase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0069288 ! PHOS_HUMAN-Phosphoserine73 [Term] id: CCO:B0055130 name: CD3Z_HUMAN def: "T-cell surface glycoprotein CD3 zeta chain precursor" [UniProtKB:P20963] synonym: "CD247 antigen" EXACT [UniProtKB:P20963] synonym: "T-cell receptor T3 zeta chain" EXACT [UniProtKB:P20963] xref: EMBL:AAA60394.1 xref: EMBL:AAH25703.1 xref: EMBL:AAY57330.1 xref: EMBL:CAH69975.1 xref: EMBL:CAI21381.1 xref: UniProtKB:P20963 xref: UniProtKB:Q5VX13 xref: UniProtKB:Q8TAX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017302 ! CD247_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015866 ! cd247-cd247-3 physical interaction relationship: participates_in CCO:I0015867 ! cd247-cd247-4 physical interaction relationship: participates_in CCO:I0017964 ! cd247-cd247 direct interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0064161 ! CD3Z_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0064162 ! CD3Z_HUMAN-Phosphotyrosine64 relationship: transforms_into CCO:B0064163 ! CD3Z_HUMAN-Phosphotyrosine72 relationship: transforms_into CCO:B0064164 ! CD3Z_HUMAN-Phosphotyrosine83 relationship: transforms_into CCO:B0064165 ! CD3Z_HUMAN-Phosphotyrosine111 relationship: transforms_into CCO:B0064166 ! CD3Z_HUMAN-Phosphotyrosine123 relationship: transforms_into CCO:B0064167 ! CD3Z_HUMAN-Phosphotyrosine142 relationship: transforms_into CCO:B0064168 ! CD3Z_HUMAN-Phosphotyrosine153 [Term] id: CCO:B0055131 name: MAL_HUMAN def: "Myelin and lymphocyte protein" [UniProtKB:P21145] synonym: "T-lymphocyte maturation-associated protein" EXACT [UniProtKB:P21145] xref: EMBL:AAA36196.1 xref: EMBL:AAH00458.1 xref: EMBL:AAH03006.1 xref: EMBL:CAA53809.1 xref: EMBL:CAA54100.1 xref: EMBL:CAA54101.1 xref: EMBL:CAA54102.1 xref: EMBL:CAA54103.1 xref: UniProtKB:P21145 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018562 ! MAL_human relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0002725 ! channel activity relationship: has_function CCO:F0003186 ! apoptotic protease activator activity relationship: has_function CCO:F0004216 ! structural constituent of myelin sheath relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0055132 name: ZNF10_HUMAN def: "Zinc finger protein 10" [UniProtKB:P21506] synonym: "Zinc finger protein KOX1" EXACT [UniProtKB:P21506] xref: EMBL:AAH24182.1 xref: EMBL:CAA36558.1 xref: UniProtKB:P21506 xref: UniProtKB:Q8TC91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020957 ! ZNF10_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017478 ! mitap1-znf10 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055133 name: CNR1_HUMAN def: "Cannabinoid receptor 1" [UniProtKB:P21554] synonym: "CANN6" EXACT [UniProtKB:P21554] synonym: "CB-R" EXACT [UniProtKB:P21554] synonym: "CB1" EXACT [UniProtKB:P21554] xref: EMBL:AAB18200.1 xref: EMBL:AAD34320.1 xref: EMBL:AAH74811.1 xref: EMBL:AAH74812.1 xref: EMBL:AAH95513.1 xref: EMBL:AAI00969.1 xref: EMBL:AAI00970.1 xref: EMBL:AAI00971.1 xref: EMBL:AAI00972.1 xref: EMBL:AAO67710.1 xref: EMBL:AAV35030.1 xref: EMBL:AAY68486.1 xref: EMBL:CAA38699.1 xref: EMBL:CAA57018.1 xref: EMBL:CAA57019.1 xref: EMBL:CAB96726.1 xref: UniProtKB:P21554 xref: UniProtKB:Q13949 xref: UniProtKB:Q495Z0 xref: UniProtKB:Q4PLI4 xref: UniProtKB:Q4VBM6 xref: UniProtKB:Q5UB37 xref: UniProtKB:Q9UNN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017410 ! CNR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001291 ! cannabinoid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055134 name: TNAP3_HUMAN def: "Tumor necrosis factor, alpha-induced protein 3" [UniProtKB:P21580] synonym: "EC 3.-.-.-" EXACT [UniProtKB:P21580] synonym: "Putative DNA-binding protein A20" EXACT [UniProtKB:P21580] synonym: "Zinc finger protein A20" EXACT [UniProtKB:P21580] xref: EMBL:AAA51550.1 xref: EMBL:AAI13872.1 xref: EMBL:AAI14481.1 xref: EMBL:AAO61093.1 xref: EMBL:CAB75664.1 xref: EMBL:CAH72937.1 xref: UniProtKB:P21580 xref: UniProtKB:Q2HIX9 xref: UniProtKB:Q5VXQ7 xref: UniProtKB:Q9NSR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020296 ! TNFAIP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016264 ! traf6-a20 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002163 ! negative regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0071438 ! TNAP3_HUMAN-Phosphoserine575 [Term] id: CCO:B0055135 name: SCF_HUMAN def: "Kit ligand precursor" [UniProtKB:P21583] synonym: "C-kit ligand" EXACT [UniProtKB:P21583] synonym: "Mast cell growth factor" EXACT [UniProtKB:P21583] synonym: "MGF" EXACT [UniProtKB:P21583] synonym: "SCF" EXACT [UniProtKB:P21583] synonym: "Stem cell factor" EXACT [UniProtKB:P21583] xref: EMBL:AAA85450.1 xref: EMBL:AAB22846.2 xref: EMBL:AAD22048.1 xref: EMBL:AAH69733.1 xref: EMBL:AAH69783.1 xref: EMBL:AAH69797.1 xref: EMBL:AAH74725.1 xref: EMBL:AAI26167.1 xref: EMBL:AAK92485.1 xref: EMBL:AAK92486.1 xref: EMBL:BAF83008.1 xref: EMBL:BAF85691.1 xref: EMBL:CAH18078.1 xref: EMBL:EAW97417.1 xref: UniProtKB:A0AV09 xref: UniProtKB:A8K2Q4 xref: UniProtKB:P21583 xref: UniProtKB:Q16487 xref: UniProtKB:Q68DZ2 xref: UniProtKB:Q7M4N8 xref: UniProtKB:Q9UQK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019845 ! KITLG_human relationship: has_function CCO:F0001474 ! stem cell factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002528 ! positive regulation of DNA replication [Term] id: CCO:B0055136 name: DRD1_HUMAN def: "D(1A) dopamine receptor" [UniProtKB:P21728] xref: EMBL:AAB26273.1 xref: EMBL:AAH74978.1 xref: EMBL:AAH74979.1 xref: EMBL:AAH96837.1 xref: EMBL:AAM18131.1 xref: EMBL:BAC05902.1 xref: EMBL:CAA39284.1 xref: EMBL:CAA39286.1 xref: EMBL:CAA41734.1 xref: UniProtKB:P21728 xref: UniProtKB:Q4QRJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017617 ! DRD1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000146 ! dopamine D1 receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000243 ! cell relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0000730 ! dopamine receptor, adenylate cyclase activating pathway relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002032 ! regulation of dopamine metabolic process relationship: participates_in CCO:P0003263 ! dopamine receptor, phospholipase C activating pathway [Term] id: CCO:B0055137 name: C5AR_HUMAN def: "C5a anaphylatoxin chemotactic receptor" [UniProtKB:P21730] synonym: "C5a-R" EXACT [UniProtKB:P21730] synonym: "C5aR" EXACT [UniProtKB:P21730] synonym: "CD88 antigen" EXACT [UniProtKB:P21730] xref: EMBL:AAA62831.1 xref: EMBL:AAD14919.1 xref: EMBL:AAH08982.1 xref: EMBL:AAO65969.1 xref: EMBL:AAP36022.1 xref: EMBL:CAA40530.1 xref: EMBL:CAB37830.1 xref: UniProtKB:P21730 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017200 ! C5AR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: transforms_into CCO:B0064026 ! C5AR_HUMAN-Sulfotyrosine11 relationship: transforms_into CCO:B0064027 ! C5AR_HUMAN-Sulfotyrosine14 relationship: transforms_into CCO:B0064028 ! C5AR_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0064029 ! C5AR_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0064030 ! C5AR_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0064031 ! C5AR_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0064032 ! C5AR_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0064033 ! C5AR_HUMAN-Phosphoserine338 [Term] id: CCO:B0055138 name: TA2R_HUMAN def: "Thromboxane A2 receptor" [UniProtKB:P21731] synonym: "Prostanoid TP receptor" EXACT [UniProtKB:P21731] synonym: "TXA2-R" EXACT [UniProtKB:P21731] xref: EMBL:AAA58957.1 xref: EMBL:AAA68608.1 xref: EMBL:AAC24303.1 xref: EMBL:AAH74749.1 xref: EMBL:AAH74750.1 xref: EMBL:AAR07905.1 xref: EMBL:ABB72549.1 xref: EMBL:BAA03649.1 xref: EMBL:BAA07274.1 xref: UniProtKB:P21731 xref: UniProtKB:Q6DK52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020119 ! TBXA2R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001301 ! thromboxane receptor activity relationship: has_function CCO:F0001302 ! thromboxane A2 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055139 name: DRD4_HUMAN def: "D(4) dopamine receptor" [UniProtKB:P21917] synonym: "D(2C) dopamine receptor" EXACT [UniProtKB:P21917] synonym: "Dopamine D4 receptor" EXACT [UniProtKB:P21917] xref: EMBL:AAB59386.1 xref: UniProtKB:P21917 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017620 ! DRD4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway [Term] id: CCO:B0055140 name: DRD5_HUMAN def: "D(1B) dopamine receptor" [UniProtKB:P21918] synonym: "D(5) dopamine receptor" EXACT [UniProtKB:P21918] synonym: "D1beta dopamine receptor" EXACT [UniProtKB:P21918] xref: EMBL:AAA52329.1 xref: EMBL:AAH09748.1 xref: EMBL:AAN01276.1 xref: EMBL:CAA41360.1 xref: UniProtKB:P21918 xref: UniProtKB:Q8NEQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017621 ! DRD5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000145 ! dopamine D5 receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_function CCO:F0005573 ! dopamine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001290 ! brush border membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0000730 ! dopamine receptor, adenylate cyclase activating pathway [Term] id: CCO:B0055141 name: TENX_HUMAN def: "Tenascin-X precursor" [UniProtKB:P22105] synonym: "Hexabrachion-like protein" EXACT [UniProtKB:P22105] synonym: "TN-X" EXACT [UniProtKB:P22105] xref: EMBL:AAA35884.1 xref: EMBL:AAB41287.1 xref: EMBL:AAB47488.1 xref: EMBL:AAB67981.1 xref: EMBL:AAC50889.1 xref: EMBL:AAH33740.1 xref: EMBL:AAI25115.1 xref: EMBL:AAI25116.1 xref: EMBL:AAI30038.1 xref: EMBL:BAD92249.1 xref: EMBL:CAA50739.1 xref: EMBL:CAA74109.1 xref: EMBL:CAA74110.1 xref: EMBL:CAB89296.1 xref: EMBL:CAB89300.1 xref: EMBL:CAI17414.1 xref: EMBL:CAI17471.1 xref: EMBL:CAI18078.1 xref: EMBL:CAI18332.1 xref: EMBL:CAQ09268.1 xref: EMBL:EAX03574.1 xref: UniProtKB:P22105 xref: UniProtKB:P78530 xref: UniProtKB:P78531 xref: UniProtKB:Q08424 xref: UniProtKB:Q08AM0 xref: UniProtKB:Q08AM1 xref: UniProtKB:Q59GU7 xref: UniProtKB:Q5SQD3 xref: UniProtKB:Q5ST74 xref: UniProtKB:Q7L8Q4 xref: UniProtKB:Q8N4R1 xref: UniProtKB:Q9NPK9 xref: UniProtKB:Q9UC10 xref: UniProtKB:Q9UC11 xref: UniProtKB:Q9UC12 xref: UniProtKB:Q9UC13 xref: UniProtKB:Q9UMG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020233 ! TNXB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071335 ! TENX_HUMAN-Phosphothreonine1331 relationship: transforms_into CCO:B0071336 ! TENX_HUMAN-Phosphothreonine1332 relationship: transforms_into CCO:B0071337 ! TENX_HUMAN-Phosphotyrosine1417 relationship: transforms_into CCO:B0071338 ! TENX_HUMAN-Phosphoserine3738 [Term] id: CCO:B0055142 name: IL10_HUMAN def: "Interleukin-10 precursor" [UniProtKB:P22301] synonym: "CSIF" EXACT [UniProtKB:P22301] synonym: "Cytokine synthesis inhibitory factor" EXACT [UniProtKB:P22301] synonym: "IL-10" EXACT [UniProtKB:P22301] xref: EMBL:AAA63207.1 xref: EMBL:AAA80104.1 xref: EMBL:AAK38162.1 xref: EMBL:AAL06594.1 xref: UniProtKB:P22301 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018247 ! IL10_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001443 ! interleukin-10 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0017266 ! il10-il10ra-1 direct interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000771 ! cytoplasmic sequestering of NF-kappaB relationship: participates_in CCO:P0000947 ! regulation of gene expression relationship: participates_in CCO:P0001349 ! negative regulation of myeloid dendritic cell activation relationship: participates_in CCO:P0002040 ! B cell proliferation relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation relationship: participates_in CCO:P0002284 ! regulation of isotype switching relationship: participates_in CCO:P0002296 ! negative regulation of interferon-alpha biosynthetic process [Term] id: CCO:B0055143 name: ACES_HUMAN def: "Acetylcholinesterase precursor" [UniProtKB:P22303] synonym: "AChE" EXACT [UniProtKB:P22303] synonym: "EC 3.1.1.7" EXACT [UniProtKB:P22303] xref: EMBL:AAA68151.1 xref: EMBL:AAC60618.1 xref: EMBL:AAH36813.1 xref: EMBL:AAH94752.1 xref: EMBL:AAI05061.1 xref: EMBL:AAI05063.1 xref: EMBL:AAK21003.1 xref: EMBL:AAO32948.1 xref: EMBL:AAP22364.1 xref: EMBL:AAP22365.1 xref: EMBL:AAU43801.1 xref: EMBL:BAF84010.1 xref: EMBL:EAL23812.1 xref: EMBL:EAL23813.1 xref: EMBL:EAW76461.1 xref: EMBL:EAW76463.1 xref: UniProtKB:A4D2E2 xref: UniProtKB:P22303 xref: UniProtKB:Q16169 xref: UniProtKB:Q29S23 xref: UniProtKB:Q2M324 xref: UniProtKB:Q504V3 xref: UniProtKB:Q86TM9 xref: UniProtKB:Q86YX9 xref: UniProtKB:Q9BXP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016884 ! ACHE_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0000475 ! acetylcholinesterase activity relationship: has_function CCO:F0000566 ! carboxylesterase activity relationship: has_function CCO:F0000576 ! cholinesterase activity relationship: has_function CCO:F0001649 ! collagen binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003609 ! serine hydrolase activity relationship: has_function CCO:F0005634 ! acetylcholine binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005826 ! laminin-1 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000228 ! basal lamina relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001561 ! negative regulation of synaptic transmission, cholinergic [Term] id: CCO:B0055144 name: CCL1_HUMAN def: "C-C motif chemokine 1 precursor" [UniProtKB:P22362] synonym: "Small-inducible cytokine A1" EXACT [UniProtKB:P22362] synonym: "T lymphocyte-secreted protein I-309" EXACT [UniProtKB:P22362] xref: EMBL:AAA52705.1 xref: EMBL:AAA61196.1 xref: EMBL:AAI05074.1 xref: EMBL:AAI05076.1 xref: UniProtKB:P22362 xref: UniProtKB:Q2M309 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017264 ! CCL1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055145 name: ENPP1_HUMAN def: "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1" [UniProtKB:P22413] synonym: "E-NPP 1" EXACT [UniProtKB:P22413] synonym: "Phosphodiesterase I/nucleotide pyrophosphatase 1" EXACT [UniProtKB:P22413] synonym: "Plasma-cell membrane glycoprotein PC-1" EXACT [UniProtKB:P22413] xref: EMBL:AAA63237.1 xref: EMBL:AAD38420.1 xref: EMBL:AAD38421.1 xref: EMBL:AAF36094.1 xref: EMBL:AAH59375.2 xref: EMBL:BAA02054.1 xref: EMBL:CAC39442.1 xref: EMBL:CAI19514.1 xref: EMBL:CAI20161.1 xref: UniProtKB:P22413 xref: UniProtKB:Q5T9R6 xref: UniProtKB:Q9NPZ3 xref: UniProtKB:Q9P1P6 xref: UniProtKB:Q9UP61 xref: UniProtKB:Q9Y6K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017714 ! ENPP1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000924 ! phosphodiesterase I activity relationship: has_function CCO:F0000937 ! nucleotide diphosphatase activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006737 ! nucleoside-triphosphate diphosphatase activity relationship: has_function CCO:F0007984 ! 3'-phosphoadenosine 5'-phosphosulfate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001513 ! negative regulation of protein amino acid autophosphorylation relationship: participates_in CCO:P0002413 ! negative regulation of fat cell differentiation relationship: participates_in CCO:P0002516 ! negative regulation of glycogen biosynthetic process relationship: participates_in CCO:P0002705 ! negative regulation of insulin receptor signaling pathway [Term] id: CCO:B0055146 name: USF1_HUMAN def: "Upstream stimulatory factor 1" [UniProtKB:P22415] synonym: "Major late transcription factor 1" EXACT [UniProtKB:P22415] xref: EMBL:AAH35505.1 xref: EMBL:AAS89301.1 xref: EMBL:BAA76541.1 xref: EMBL:CAA39201.1 xref: EMBL:CAI15372.1 xref: UniProtKB:P22415 xref: UniProtKB:Q5SY46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020421 ! USF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005853 ! bHLH transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000433 ! regulation of transcription from RNA polymerase II promoter by glucose relationship: participates_in CCO:P0000435 ! positive regulation of transcription from RNA polymerase II promoter by glucose relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055147 name: FGFR4_HUMAN def: "Fibroblast growth factor receptor 4 precursor" [UniProtKB:P22455] synonym: "CD334 antigen" EXACT [UniProtKB:P22455] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P22455] synonym: "FGFR-4" EXACT [UniProtKB:P22455] xref: EMBL:AAA63208.1 xref: EMBL:AAB59389.1 xref: EMBL:AAF27432.1 xref: EMBL:AAH11847.1 xref: EMBL:AAM13666.1 xref: EMBL:ABQ01235.1 xref: EMBL:CAA40490.1 xref: EMBL:CAA74200.1 xref: EMBL:EAW85036.1 xref: UniProtKB:O43785 xref: UniProtKB:P22455 xref: UniProtKB:Q14309 xref: UniProtKB:Q71TW8 xref: UniProtKB:Q8TDA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017801 ! FGFR4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001344 ! fibroblast growth factor receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: transforms_into CCO:B0066185 ! FGFR4_HUMAN-Phosphotyrosine643 [Term] id: CCO:B0055148 name: GALA_HUMAN def: "Galanin precursor" [UniProtKB:P22466] xref: EMBL:AAA18248.1 xref: EMBL:AAA60178.1 xref: EMBL:AAH30241.1 xref: UniProtKB:P22466 xref: UniProtKB:Q14413 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017859 ! GAL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001503 ! regulation of glucocorticoid metabolic process relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002916 ! negative regulation of lymphocyte proliferation relationship: transforms_into CCO:B0066362 ! GALA_HUMAN-Phosphoserine117 [Term] id: CCO:B0055149 name: IBP4_HUMAN def: "Insulin-like growth factor-binding protein 4 precursor" [UniProtKB:P22692] synonym: "IBP-4" EXACT [UniProtKB:P22692] synonym: "IGF-binding protein 4" EXACT [UniProtKB:P22692] synonym: "IGFBP-4" EXACT [UniProtKB:P22692] xref: EMBL:AAA62670.1 xref: EMBL:AAB06189.1 xref: EMBL:AAH16041.1 xref: EMBL:AAR05443.1 xref: EMBL:AAV38695.1 xref: UniProtKB:P22692 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018210 ! IGFBP4_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055150 name: NR4A1_HUMAN def: "Nuclear receptor subfamily 4 group A member 1" [UniProtKB:P22736] synonym: "Early response protein NAK1" EXACT [UniProtKB:P22736] synonym: "Orphan nuclear receptor HMR" EXACT [UniProtKB:P22736] synonym: "ST-59" EXACT [UniProtKB:P22736] synonym: "TR3 orphan receptor" EXACT [UniProtKB:P22736] xref: EMBL:AAA36763.1 xref: EMBL:AAH16147.1 xref: EMBL:BAA08565.1 xref: UniProtKB:P22736 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018860 ! NR4A1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0019053 ! atxn1-nr4a1 physical interaction relationship: participates_in CCO:I0020385 ! nr4a1-fxyd3 physical interaction relationship: participates_in CCO:I0020442 ! rps6ka6-nr4a1 physical interaction relationship: participates_in CCO:I0020556 ! kiaa1626-nr4a1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068822 ! NR4A1_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0068823 ! NR4A1_HUMAN-Phosphoserine351 [Term] id: CCO:B0055151 name: CPN2_HUMAN def: "Carboxypeptidase N subunit 2 precursor" [UniProtKB:P22792] synonym: "Carboxypeptidase N 83 kDa chain" EXACT [UniProtKB:P22792] synonym: "Carboxypeptidase N large subunit" EXACT [UniProtKB:P22792] synonym: "Carboxypeptidase N polypeptide 2" EXACT [UniProtKB:P22792] synonym: "Carboxypeptidase N regulatory subunit" EXACT [UniProtKB:P22792] xref: EMBL:AAA51921.2 xref: EMBL:AAH31569.2 xref: EMBL:AAH42334.2 xref: UniProtKB:P22792 xref: UniProtKB:Q86SU4 xref: UniProtKB:Q8N5V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017441 ! CPN2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0055152 name: LSHR_HUMAN def: "Lutropin-choriogonadotropic hormone receptor precursor" [UniProtKB:P22888] synonym: "LH/CG-R" EXACT [UniProtKB:P22888] synonym: "LHR" EXACT [UniProtKB:P22888] synonym: "LSH-R" EXACT [UniProtKB:P22888] synonym: "Luteinizing hormone receptor" EXACT [UniProtKB:P22888] xref: EMBL:AAA59515.1 xref: EMBL:AAA70231.1 xref: EMBL:AAB19917.2 xref: EMBL:AAB88417.1 xref: EMBL:AAC98291.1 xref: EMBL:CAA59234.1 xref: UniProtKB:P22888 xref: UniProtKB:Q14751 xref: UniProtKB:Q15996 xref: UniProtKB:Q9UEW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018525 ! LHCGR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001305 ! lutropin-choriogonadotropic hormone receptor activity relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055153 name: TCEA1_HUMAN def: "Transcription elongation factor A protein 1" [UniProtKB:P23193] synonym: "Transcription elongation factor S-II protein 1" EXACT [UniProtKB:P23193] synonym: "Transcription elongation factor TFIIS.o" EXACT [UniProtKB:P23193] xref: EMBL:AAA61138.1 xref: EMBL:AAH72460.1 xref: EMBL:AAV38798.1 xref: EMBL:CAA40484.1 xref: EMBL:CAA44470.1 xref: EMBL:CAA51940.1 xref: EMBL:CAG47017.1 xref: UniProtKB:P23193 xref: UniProtKB:Q15563 xref: UniProtKB:Q6FG87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020210 ! TCEA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071258 ! TCEA1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0071259 ! TCEA1_HUMAN-Phosphoserine81 relationship: transforms_into CCO:B0071260 ! TCEA1_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0071261 ! TCEA1_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0071262 ! TCEA1_HUMAN-Phosphothreonine108 relationship: transforms_into CCO:B0071263 ! TCEA1_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0071264 ! TCEA1_HUMAN-Phosphotyrosine126 [Term] id: CCO:B0055154 name: ITA6_HUMAN def: "Integrin alpha-6 precursor" [UniProtKB:P23229] synonym: "CD49 antigen-like family member F" EXACT [UniProtKB:P23229] synonym: "CD49f antigen" EXACT [UniProtKB:P23229] synonym: "VLA-6" EXACT [UniProtKB:P23229] xref: EMBL:AAB20354.1 xref: EMBL:AAB20355.1 xref: EMBL:AAB24829.1 xref: EMBL:AAD48469.1 xref: EMBL:CAA37655.1 xref: EMBL:CAA42099.1 xref: UniProtKB:P23229 xref: UniProtKB:Q08443 xref: UniProtKB:Q14646 xref: UniProtKB:Q16508 xref: UniProtKB:Q9UN03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018336 ! ITGA6_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0055155 name: S10A1_HUMAN def: "Protein S100-A1" [UniProtKB:P23297] synonym: "S-100 protein alpha chain" EXACT [UniProtKB:P23297] synonym: "S-100 protein alpha subunit" EXACT [UniProtKB:P23297] synonym: "S100 calcium-binding protein A1" EXACT [UniProtKB:P23297] xref: EMBL:AAH14392.1 xref: EMBL:AAP35584.1 xref: EMBL:CAA41107.1 xref: EMBL:CAI19677.1 xref: UniProtKB:P23297 xref: UniProtKB:Q5T7Y3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019818 ! S100A1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007315 ! S100 beta binding relationship: has_function CCO:F0007316 ! S100 alpha binding relationship: has_function CCO:F0008060 ! ATPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000802 ! sarcoplasmic reticulum relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0015074 ! s100a1-s100p physical interaction relationship: participates_in CCO:I0015394 ! s100a1-s100a1 physical interaction relationship: participates_in CCO:I0015572 ! nif3l1-s100a1 physical interaction relationship: participates_in CCO:I0015841 ! s100a1-s100b physical interaction relationship: participates_in CCO:I0015852 ! s100a1-s100a4 physical interaction relationship: participates_in CCO:I0015973 ! s100a1-s100b-1 physical interaction relationship: participates_in CCO:I0016005 ! s100a1-s100p-3 direct interaction relationship: participates_in CCO:I0016194 ! s100b-s100a1-1 physical interaction relationship: participates_in CCO:I0017922 ! s100a1-s100a1-1 physical interaction relationship: participates_in CCO:I0017923 ! s100a1-s100b-2 physical interaction relationship: participates_in CCO:I0017925 ! s100b-s100a1-2 physical interaction relationship: participates_in CCO:I0017960 ! s100a1-s100p-1 physical interaction relationship: participates_in CCO:I0017961 ! s100a1-s100a1-4 physical interaction relationship: participates_in CCO:I0019186 ! s100a1-s100p-2 physical interaction relationship: participates_in CCO:I0019187 ! s100a1-s100p-7 physical interaction relationship: participates_in CCO:I0019327 ! s100a1-s100p-4 colocalization relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055156 name: MYF6_HUMAN def: "Myogenic factor 6" [UniProtKB:P23409] synonym: "Myf-6" EXACT [UniProtKB:P23409] xref: EMBL:AAH17834.1 xref: EMBL:CAA36260.1 xref: EMBL:CAG28569.1 xref: EMBL:CAG46563.1 xref: UniProtKB:P23409 xref: UniProtKB:Q53X80 xref: UniProtKB:Q6FHI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018697 ! MYF6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0055157 name: PTPRD_HUMAN def: "Receptor-type tyrosine-protein phosphatase delta precursor" [UniProtKB:P23468] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P23468] synonym: "Protein-tyrosine phosphatase delta" EXACT [UniProtKB:P23468] synonym: "R-PTP-delta" EXACT [UniProtKB:P23468] xref: EMBL:AAC41749.1 xref: EMBL:CAA38068.1 xref: EMBL:CAH70443.2 xref: EMBL:CAH70912.2 xref: EMBL:CAH73128.2 xref: EMBL:CAH73847.2 xref: EMBL:CAI16146.2 xref: UniProtKB:B1ALA0 xref: UniProtKB:P23468 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019549 ! PTPRD_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000725 ! transmembrane receptor protein tyrosine phosphatase signaling pathway [Term] id: CCO:B0055158 name: PTPRG_HUMAN def: "Receptor-type tyrosine-protein phosphatase gamma precursor" [UniProtKB:P23470] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P23470] synonym: "Protein-tyrosine phosphatase gamma" EXACT [UniProtKB:P23470] synonym: "R-PTP-gamma" EXACT [UniProtKB:P23470] xref: EMBL:AAA60224.1 xref: EMBL:AAC50439.1 xref: EMBL:BAD93108.1 xref: EMBL:CAA38067.1 xref: EMBL:CAH18125.1 xref: UniProtKB:P23470 xref: UniProtKB:Q15623 xref: UniProtKB:Q59EE0 xref: UniProtKB:Q68DU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019551 ! PTPRG_human relationship: has_function CCO:F0000564 ! carbonate dehydratase activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0069604 ! PTPRG_HUMAN-Phosphothreonine115 [Term] id: CCO:B0055159 name: SP100_HUMAN def: "Nuclear autoantigen Sp-100" [UniProtKB:P23497] synonym: "Lysp100b" EXACT [UniProtKB:P23497] synonym: "Nuclear dot-associated Sp100 protein" EXACT [UniProtKB:P23497] synonym: "Speckled 100 kDa" EXACT [UniProtKB:P23497] xref: EMBL:AAA35537.1 xref: EMBL:AAC39790.1 xref: EMBL:AAC50743.1 xref: EMBL:AAF39781.1 xref: EMBL:AAH11562.1 xref: EMBL:AAK51202.1 xref: EMBL:AAK57703.1 xref: EMBL:AAL77438.1 xref: EMBL:AAL77439.1 xref: EMBL:CAA64744.1 xref: UniProtKB:O75450 xref: UniProtKB:P23497 xref: UniProtKB:Q13343 xref: UniProtKB:Q96F70 xref: UniProtKB:Q96T24 xref: UniProtKB:Q96T95 xref: UniProtKB:Q9NP33 xref: UniProtKB:Q9UE32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019996 ! SP100_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015691 ! sp100-sumo1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070754 ! SP100_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0070755 ! SP100_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0070756 ! SP100_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0070757 ! SP100_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0070758 ! SP100_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0070759 ! SP100_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0070760 ! SP100_HUMAN-Phosphothreonine335 relationship: transforms_into CCO:B0070761 ! SP100_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0070762 ! SP100_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0070763 ! SP100_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0070764 ! SP100_HUMAN-Phosphoserine451 relationship: transforms_into CCO:B0070765 ! SP100_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0070766 ! SP100_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0070767 ! SP100_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0070768 ! SP100_HUMAN-Phosphoserine459 [Term] id: CCO:B0055160 name: TNFL4_HUMAN def: "Tumor necrosis factor ligand superfamily member 4" [UniProtKB:P23510] synonym: "CD252 antigen" EXACT [UniProtKB:P23510] synonym: "Glycoprotein Gp34" EXACT [UniProtKB:P23510] synonym: "OX40 ligand" EXACT [UniProtKB:P23510] synonym: "OX40L" EXACT [UniProtKB:P23510] synonym: "TAX transcriptionally-activated glycoprotein 1" EXACT [UniProtKB:P23510] xref: EMBL:BAA14259.1 xref: EMBL:BAB18304.1 xref: EMBL:CAA18438.2 xref: EMBL:CAA56284.1 xref: UniProtKB:P23510 xref: UniProtKB:Q9HCN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020303 ! TNFSF4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055161 name: IP3KA_HUMAN def: "Inositol-trisphosphate 3-kinase A" [UniProtKB:P23677] synonym: "EC 2.7.1.127" EXACT [UniProtKB:P23677] synonym: "Inositol 1,4,5-trisphosphate 3-kinase A" EXACT [UniProtKB:P23677] synonym: "IP3 3-kinase A" EXACT [UniProtKB:P23677] synonym: "IP3K A" EXACT [UniProtKB:P23677] xref: EMBL:AAH26331.1 xref: EMBL:CAA38700.1 xref: UniProtKB:P23677 xref: UniProtKB:Q8TAN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018298 ! ITPKA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001903 ! inositol trisphosphate 3-kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055162 name: DGKA_HUMAN def: "Diacylglycerol kinase alpha" [UniProtKB:P23743] synonym: "80 kDa diacylglycerol kinase" EXACT [UniProtKB:P23743] synonym: "DAG kinase alpha" EXACT [UniProtKB:P23743] synonym: "DGK-alpha" EXACT [UniProtKB:P23743] synonym: "Diglyceride kinase alpha" EXACT [UniProtKB:P23743] synonym: "EC 2.7.1.107" EXACT [UniProtKB:P23743] xref: EMBL:AAC34802.1 xref: EMBL:AAC34803.1 xref: EMBL:AAC34804.1 xref: EMBL:AAC34806.1 xref: EMBL:AAH23523.1 xref: EMBL:AAH31870.1 xref: EMBL:CAA44396.1 xref: UniProtKB:O75481 xref: UniProtKB:O75482 xref: UniProtKB:O75483 xref: UniProtKB:O95217 xref: UniProtKB:P23743 xref: UniProtKB:Q8IZ56 xref: UniProtKB:Q8N5Q2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017564 ! DGKA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064751 ! DGKA_HUMAN-Phosphotyrosine22 [Term] id: CCO:B0055163 name: PAX7_HUMAN def: "Paired box protein Pax-7" [UniProtKB:P23759] synonym: "HUP1" EXACT [UniProtKB:P23759] xref: EMBL:CAA16432.1 xref: EMBL:CAA65520.1 xref: EMBL:CAA65521.1 xref: EMBL:CAA65522.1 xref: EMBL:CAA84513.1 xref: UniProtKB:P23759 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019310 ! PAX7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055164 name: PAX3_HUMAN def: "Paired box protein Pax-3" [UniProtKB:P23760] synonym: "HUP2" EXACT [UniProtKB:P23760] xref: EMBL:AAA80573.1 xref: EMBL:AAA80574.1 xref: EMBL:AAA91849.1 xref: EMBL:AAB21476.1 xref: EMBL:AAB30167.1 xref: EMBL:AAB30168.1 xref: EMBL:CAA33145.1 xref: UniProtKB:P23760 xref: UniProtKB:Q16448 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019307 ! PAX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055165 name: GATA2_HUMAN def: "Endothelial transcription factor GATA-2" [UniProtKB:P23769] synonym: "GATA-binding protein 2" EXACT [UniProtKB:P23769] xref: EMBL:AAA35868.1 xref: EMBL:AAA35869.1 xref: EMBL:AAH02557.1 xref: UniProtKB:P23769 xref: UniProtKB:Q9BUJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017870 ! GATA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis [Term] id: CCO:B0055166 name: GATA3_HUMAN def: "Trans-acting T-cell-specific transcription factor GATA-3" [UniProtKB:P23771] synonym: "GATA-binding factor 3" EXACT [UniProtKB:P23771] xref: EMBL:AAA35870.1 xref: EMBL:AAH03070.1 xref: EMBL:AAH06793.1 xref: EMBL:AAR32096.1 xref: EMBL:CAA38877.1 xref: EMBL:CAA38916.1 xref: EMBL:CAA41102.1 xref: UniProtKB:P23771 xref: UniProtKB:Q96J16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017871 ! GATA3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0055167 name: CPT2_HUMAN def: "Carnitine O-palmitoyltransferase 2, mitochondrial precursor" [UniProtKB:P23786] synonym: "Carnitine palmitoyltransferase II" EXACT [UniProtKB:P23786] synonym: "CPT II" EXACT [UniProtKB:P23786] synonym: "EC 2.3.1.21" EXACT [UniProtKB:P23786] xref: EMBL:AAB59462.1 xref: EMBL:AAB60382.1 xref: EMBL:AAB60383.1 xref: EMBL:AAH02445.1 xref: EMBL:AAH05172.1 xref: EMBL:CAI18907.1 xref: UniProtKB:P23786 xref: UniProtKB:Q5SW68 xref: UniProtKB:Q9BQ26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017444 ! CPT2_human relationship: has_function CCO:F0000568 ! carnitine O-palmitoyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation relationship: transforms_into CCO:B0064457 ! CPT2_HUMAN-N6-acetyllysine544 [Term] id: CCO:B0055168 name: PRTN3_HUMAN def: "Myeloblastin precursor" [UniProtKB:P24158] synonym: "AGP7" EXACT [UniProtKB:P24158] synonym: "C-ANCA antigen" EXACT [UniProtKB:P24158] synonym: "EC 3.4.21.76" EXACT [UniProtKB:P24158] synonym: "Leukocyte proteinase 3" EXACT [UniProtKB:P24158] synonym: "Neutrophil proteinase 4" EXACT [UniProtKB:P24158] synonym: "NP-4" EXACT [UniProtKB:P24158] synonym: "P29" EXACT [UniProtKB:P24158] synonym: "PR-3" EXACT [UniProtKB:P24158] synonym: "PR3" EXACT [UniProtKB:P24158] synonym: "Wegener autoantigen" EXACT [UniProtKB:P24158] xref: EMBL:AAA36342.1 xref: EMBL:AAA59558.1 xref: EMBL:AAB59364.1 xref: EMBL:AAB59493.1 xref: EMBL:AAD21524.1 xref: EMBL:AAH96183.1 xref: EMBL:AAH96185.1 xref: EMBL:CAA39203.1 xref: EMBL:CAA39598.1 xref: EMBL:CAA39943.1 xref: UniProtKB:P15637 xref: UniProtKB:P18078 xref: UniProtKB:P24158 xref: UniProtKB:Q4VB09 xref: UniProtKB:Q6LBM7 xref: UniProtKB:Q9UQD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019523 ! PRTN3_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0008972 ! smad3-prtn3 physical interaction relationship: participates_in CCO:I0008973 ! smad3-prtn3-2 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055169 name: ZBT25_HUMAN def: "Zinc finger and BTB domain-containing protein 25" [UniProtKB:P24278] synonym: "Zinc finger protein 46" EXACT [UniProtKB:P24278] synonym: "Zinc finger protein KUP" EXACT [UniProtKB:P24278] xref: EMBL:AAH35804.1 xref: EMBL:CAA34595.1 xref: UniProtKB:P24278 xref: UniProtKB:Q8IYH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020550 ! ZBTB25_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014955 ! traf2-zbtb25 physical interaction relationship: participates_in CCO:I0015203 ! mdfi-zbtb25 physical interaction relationship: participates_in CCO:I0015402 ! mgc2749-zbtb25 physical interaction relationship: participates_in CCO:I0015521 ! scam_1-zbtb25 physical interaction relationship: participates_in CCO:I0017578 ! zbtb25-coil physical interaction relationship: participates_in CCO:I0019423 ! zbtb25-mdf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055170 name: CRHBP_HUMAN def: "Corticotropin-releasing factor-binding protein precursor" [UniProtKB:P24387] synonym: "Corticotropin-releasing hormone-binding protein" EXACT [UniProtKB:P24387] synonym: "CRF-binding protein" EXACT [UniProtKB:P24387] synonym: "CRF-BP" EXACT [UniProtKB:P24387] synonym: "CRH-BP" EXACT [UniProtKB:P24387] xref: EMBL:AAD13916.1 xref: EMBL:AAH18038.1 xref: EMBL:CAA41086.1 xref: UniProtKB:P24387 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017457 ! CRHBP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003530 ! adrenocorticotropin-releasing hormone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055171 name: IL4RA_HUMAN def: "Interleukin-4 receptor alpha chain precursor" [UniProtKB:P24394] synonym: "CD124 antigen" EXACT [UniProtKB:P24394] synonym: "IL-4R-alpha" EXACT [UniProtKB:P24394] xref: EMBL:AAC23495.1 xref: EMBL:AAL12163.1 xref: EMBL:CAA36672.1 xref: EMBL:CAC20445.1 xref: EMBL:CAC20446.1 xref: EMBL:CAC20447.1 xref: EMBL:CAC20448.1 xref: EMBL:CAC20449.1 xref: EMBL:CAC20450.1 xref: EMBL:CAC20451.1 xref: EMBL:CAC20452.1 xref: UniProtKB:P24394 xref: UniProtKB:Q96P01 xref: UniProtKB:Q9H181 xref: UniProtKB:Q9H182 xref: UniProtKB:Q9H183 xref: UniProtKB:Q9H184 xref: UniProtKB:Q9H185 xref: UniProtKB:Q9H186 xref: UniProtKB:Q9H187 xref: UniProtKB:Q9H188 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018264 ! IL4R_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017788 ! il4-il4r-1 direct interaction relationship: participates_in CCO:I0017844 ! il2rg-il4r-1 physical interaction relationship: participates_in CCO:I0017845 ! il4r-il4-1 physical interaction relationship: participates_in CCO:I0017846 ! il4r-il4-2 physical interaction relationship: participates_in CCO:I0017980 ! il4r-il4-3 physical interaction relationship: participates_in CCO:I0019898 ! arih2-il4r physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067076 ! IL4RA_HUMAN-Phosphotyrosine497 relationship: transforms_into CCO:B0067077 ! IL4RA_HUMAN-Phosphotyrosine575 relationship: transforms_into CCO:B0067078 ! IL4RA_HUMAN-Phosphotyrosine603 relationship: transforms_into CCO:B0067079 ! IL4RA_HUMAN-Phosphotyrosine631 [Term] id: CCO:B0055172 name: AKAP5_HUMAN def: "A-kinase anchor protein 5" [UniProtKB:P24588] synonym: "A-kinase anchor protein 79 kDa" EXACT [UniProtKB:P24588] synonym: "AKAP 79" EXACT [UniProtKB:P24588] synonym: "cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein" EXACT [UniProtKB:P24588] synonym: "H21" EXACT [UniProtKB:P24588] xref: EMBL:AAA58363.1 xref: UniProtKB:P24588 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016945 ! AKAP5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0008036 ! protein kinase A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0016310 ! irk2-akap5-3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055173 name: IBP6_HUMAN def: "Insulin-like growth factor-binding protein 6 precursor" [UniProtKB:P24592] synonym: "IBP-6" EXACT [UniProtKB:P24592] synonym: "IGF-binding protein 6" EXACT [UniProtKB:P24592] synonym: "IGFBP-6" EXACT [UniProtKB:P24592] xref: EMBL:AAA88070.1 xref: EMBL:AAB06187.1 xref: EMBL:AAH03507.1 xref: EMBL:AAH05007.1 xref: EMBL:AAH10162.1 xref: EMBL:AAH11708.1 xref: EMBL:AAR05445.1 xref: EMBL:CAA07346.1 xref: UniProtKB:P24592 xref: UniProtKB:Q14492 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018212 ! IGFBP6_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0017532 ! igfbp6-ubqln4 physical interaction relationship: participates_in CCO:I0018891 ! ubqln4-igfbp6 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055174 name: IBP5_HUMAN def: "Insulin-like growth factor-binding protein 5 precursor" [UniProtKB:P24593] synonym: "IBP-5" EXACT [UniProtKB:P24593] synonym: "IGF-binding protein 5" EXACT [UniProtKB:P24593] synonym: "IGFBP-5" EXACT [UniProtKB:P24593] xref: EMBL:AAA53505.1 xref: EMBL:AAA72051.1 xref: EMBL:AAC09368.1 xref: EMBL:AAD04730.1 xref: EMBL:AAH11453.1 xref: EMBL:AAS16353.1 xref: EMBL:AAV38512.1 xref: EMBL:AAV38513.1 xref: UniProtKB:P24593 xref: UniProtKB:Q5U0A3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018211 ! IGFBP5_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004919 ! insulin-like growth factor I binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000829 ! insulin-like growth factor binding protein complex relationship: participates_in CCO:I0020340 ! igfbp5-bat3 physical interaction relationship: participates_in CCO:I0020576 ! igfbp5-loc56902 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001109 ! negative regulation of smooth muscle cell migration relationship: participates_in CCO:P0002247 ! negative regulation of insulin-like growth factor receptor signaling pathway relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation [Term] id: CCO:B0055175 name: CXCR1_HUMAN def: "High affinity interleukin-8 receptor A" [UniProtKB:P25024] synonym: "CD181 antigen" EXACT [UniProtKB:P25024] synonym: "CDw128a" EXACT [UniProtKB:P25024] synonym: "CXCR-1" EXACT [UniProtKB:P25024] synonym: "IL-8 receptor type 1" EXACT [UniProtKB:P25024] synonym: "IL-8R A" EXACT [UniProtKB:P25024] xref: EMBL:AAA59159.1 xref: EMBL:AAA59160.1 xref: EMBL:AAA64378.1 xref: EMBL:AAB59436.1 xref: EMBL:AAH28221.1 xref: EMBL:AAH72397.1 xref: EMBL:AAT46689.1 xref: EMBL:AAX93212.1 xref: EMBL:AAY21512.1 xref: EMBL:AAY21513.1 xref: EMBL:AAY21514.1 xref: EMBL:AAY21515.1 xref: EMBL:AAY21516.1 xref: EMBL:AAY21519.1 xref: EMBL:AAY21522.1 xref: EMBL:AAY21523.1 xref: EMBL:BAA92290.1 xref: EMBL:BAA92291.1 xref: EMBL:BAA92292.1 xref: EMBL:BAA92293.1 xref: EMBL:BAA92294.1 xref: EMBL:CAA46688.1 xref: EMBL:CAG46791.1 xref: EMBL:CAG46826.1 xref: UniProtKB:P25024 xref: UniProtKB:Q2YEF8 xref: UniProtKB:Q2YEG4 xref: UniProtKB:Q2YEG5 xref: UniProtKB:Q2YEG7 xref: UniProtKB:Q2YEG8 xref: UniProtKB:Q53R18 xref: UniProtKB:Q6IN95 xref: UniProtKB:Q8N6T6 xref: UniProtKB:Q9P2T8 xref: UniProtKB:Q9P2T9 xref: UniProtKB:Q9P2U0 xref: UniProtKB:Q9P2U1 xref: UniProtKB:Q9P2U2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017497 ! IL8RA_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001264 ! interleukin-8 receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055176 name: CXCR2_HUMAN def: "High affinity interleukin-8 receptor B" [UniProtKB:P25025] synonym: "CD182 antigen" EXACT [UniProtKB:P25025] synonym: "CDw128b" EXACT [UniProtKB:P25025] synonym: "CXCR-2" EXACT [UniProtKB:P25025] synonym: "GRO/MGSA receptor" EXACT [UniProtKB:P25025] synonym: "IL-8 receptor type 2" EXACT [UniProtKB:P25025] synonym: "IL-8R B" EXACT [UniProtKB:P25025] xref: EMBL:AAA36108.1 xref: EMBL:AAA83148.1 xref: EMBL:AAB59437.1 xref: EMBL:AAB60656.1 xref: EMBL:AAC14460.1 xref: EMBL:AAH37961.2 xref: EMBL:AAT97985.1 xref: EMBL:BAA92295.1 xref: EMBL:BAA92296.1 xref: UniProtKB:P25025 xref: UniProtKB:Q8IUZ1 xref: UniProtKB:Q9P2T6 xref: UniProtKB:Q9P2T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017498 ! IL8RB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0064597 ! CXCR2_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0064599 ! CXCR2_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0064600 ! CXCR2_HUMAN-Phosphoserine353 [Term] id: CCO:B0055177 name: CD24_HUMAN def: "Signal transducer CD24 precursor" [UniProtKB:P25063] synonym: "CD24 antigen" EXACT [UniProtKB:P25063] synonym: "Small cell lung carcinoma cluster 4 antigen" EXACT [UniProtKB:P25063] xref: EMBL:AAA35665.1 xref: EMBL:AAB58807.1 xref: EMBL:AAD14170.1 xref: EMBL:AAH64619.1 xref: EMBL:AAP36068.1 xref: EMBL:CAA49195.1 xref: UniProtKB:P25063 xref: UniProtKB:Q16257 xref: UniProtKB:Q53XS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017292 ! CD24_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004356 ! carbohydrate binding relationship: has_function CCO:F0004383 ! protein tyrosine kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001218 ! anchored to external side of plasma membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000511 ! regulation of cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0000582 ! immune response-regulating cell surface receptor signaling pathway relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001342 ! regulation of epithelial cell differentiation relationship: participates_in CCO:P0001401 ! T cell costimulation relationship: participates_in CCO:P0002043 ! positive regulation of activated T cell proliferation relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: participates_in CCO:P0002209 ! regulation of MAPKKK cascade [Term] id: CCO:B0055178 name: FPR3_HUMAN def: "N-formyl peptide receptor 3" [UniProtKB:P25089] synonym: "FMLP-R-II" EXACT [UniProtKB:P25089] synonym: "FMLP-related receptor II" EXACT [UniProtKB:P25089] synonym: "Formyl peptide receptor-like 2" EXACT [UniProtKB:P25089] xref: EMBL:AAA52474.1 xref: EMBL:AAA58482.1 xref: EMBL:AAH59388.1 xref: EMBL:AAH69070.1 xref: EMBL:AAH69593.1 xref: EMBL:AAH69812.1 xref: EMBL:AAP20654.1 xref: UniProtKB:P25089 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017830 ! FPR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055179 name: FPR2_HUMAN def: "N-formyl peptide receptor 2" [UniProtKB:P25090] synonym: "FMLP-R-I" EXACT [UniProtKB:P25090] synonym: "FMLP-related receptor I" EXACT [UniProtKB:P25090] synonym: "Formyl peptide receptor-like 1" EXACT [UniProtKB:P25090] synonym: "HM63" EXACT [UniProtKB:P25090] synonym: "Lipoxin A4 receptor" EXACT [UniProtKB:P25090] synonym: "LXA4 receptor" EXACT [UniProtKB:P25090] synonym: "RFP" EXACT [UniProtKB:P25090] xref: EMBL:AAA52473.1 xref: EMBL:AAA58481.1 xref: EMBL:AAA60070.1 xref: EMBL:AAB51133.1 xref: EMBL:AAC13684.1 xref: EMBL:AAF87844.1 xref: EMBL:AAH29125.1 xref: EMBL:AAH71722.1 xref: EMBL:AAO67711.1 xref: EMBL:BAA01720.1 xref: EMBL:CAA45319.1 xref: UniProtKB:P25090 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017829 ! FPR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055180 name: ARBK1_HUMAN def: "Beta-adrenergic receptor kinase 1" [UniProtKB:P25098] synonym: "Beta-ARK-1" EXACT [UniProtKB:P25098] synonym: "EC 2.7.11.15" EXACT [UniProtKB:P25098] synonym: "G-protein coupled receptor kinase 2" EXACT [UniProtKB:P25098] xref: EMBL:AAA58391.1 xref: EMBL:AAB60689.1 xref: EMBL:AAH37963.1 xref: EMBL:AAH90863.1 xref: EMBL:CAA43470.1 xref: UniProtKB:P25098 xref: UniProtKB:Q13837 xref: UniProtKB:Q6GTT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016999 ! ADRBK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006998 ! beta-adrenergic receptor kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000518 ! desensitization of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway relationship: participates_in CCO:P0001840 ! positive regulation of catecholamine secretion relationship: transforms_into CCO:B0065696 ! ARBK1_HUMAN-Phosphoserine670 [Term] id: CCO:B0055181 name: PTAFR_HUMAN def: "Platelet-activating factor receptor" [UniProtKB:P25105] synonym: "PAF-R" EXACT [UniProtKB:P25105] xref: EMBL:AAA60001.1 xref: EMBL:AAA60002.1 xref: EMBL:AAA60108.1 xref: EMBL:AAA60214.1 xref: EMBL:AAB24695.2 xref: EMBL:AAB25755.1 xref: EMBL:AAH13816.1 xref: EMBL:AAH63000.1 xref: EMBL:AAP32298.1 xref: EMBL:AAP88803.1 xref: EMBL:BAA01050.1 xref: UniProtKB:A3KMC8 xref: UniProtKB:P25105 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019537 ! PTAFR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001330 ! platelet activating factor receptor activity relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0055182 name: CXCR7_HUMAN def: "C-X-C chemokine receptor type 7" [UniProtKB:P25106] synonym: "Chemokine orphan receptor 1" EXACT [UniProtKB:P25106] synonym: "CXC-R7" EXACT [UniProtKB:P25106] synonym: "CXCR-7" EXACT [UniProtKB:P25106] synonym: "G-protein coupled receptor 159" EXACT [UniProtKB:P25106] synonym: "G-protein coupled receptor RDC1 homolog" EXACT [UniProtKB:P25106] synonym: "RDC-1" EXACT [UniProtKB:P25106] xref: EMBL:AAA62370.1 xref: EMBL:AAB16913.1 xref: EMBL:AAB18130.1 xref: EMBL:AAB94130.1 xref: EMBL:AAH36661.1 xref: EMBL:AAX93086.1 xref: EMBL:ABH01258.1 xref: UniProtKB:P25106 xref: UniProtKB:Q53RV4 xref: UniProtKB:Q8NE10 xref: UniProtKB:Q92938 xref: UniProtKB:Q92986 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017503 ! CXCR7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055183 name: ZA2G_HUMAN def: "Zinc-alpha-2-glycoprotein precursor" [UniProtKB:P25311] synonym: "Zn-alpha-2-glycoprotein" EXACT [UniProtKB:P25311] synonym: "Zn-alpha-2-GP" EXACT [UniProtKB:P25311] xref: EMBL:AAA61311.1 xref: EMBL:AAH05306.1 xref: EMBL:AAH33830.1 xref: EMBL:BAA03123.1 xref: EMBL:BAA14417.1 xref: EMBL:CAA42438.1 xref: EMBL:CAA49574.1 xref: EMBL:EAL23862.1 xref: EMBL:EAW76621.1 xref: UniProtKB:O60386 xref: UniProtKB:P25311 xref: UniProtKB:Q5XKQ4 xref: UniProtKB:Q8N4N0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020541 ! AZGP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0071946 ! ZA2G_HUMAN-Pyrrolidone carboxylic acid18 [Term] id: CCO:B0055184 name: LAMA1_HUMAN def: "Laminin subunit alpha-1 precursor" [UniProtKB:P25391] synonym: "Laminin A chain" EXACT [UniProtKB:P25391] xref: EMBL:CAA41418.1 xref: UniProtKB:P25391 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018452 ! LAMA1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0000231 ! laminin-3 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0055185 name: MT3_HUMAN def: "Metallothionein-3" [UniProtKB:P25713] synonym: "GIF" EXACT [UniProtKB:P25713] synonym: "GIFB" EXACT [UniProtKB:P25713] synonym: "Growth inhibitory factor" EXACT [UniProtKB:P25713] synonym: "Metallothionein-III" EXACT [UniProtKB:P25713] synonym: "MT-3" EXACT [UniProtKB:P25713] synonym: "MT-III" EXACT [UniProtKB:P25713] xref: EMBL:AAA36214.1 xref: EMBL:AAB31396.1 xref: EMBL:AAH13081.1 xref: EMBL:AAP35677.1 xref: EMBL:ABB84467.1 xref: EMBL:CAA61763.1 xref: UniProtKB:P25713 xref: UniProtKB:Q2V574 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018669 ! MT3_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002946 ! negative regulation of neurogenesis relationship: transforms_into CCO:B0068305 ! MT3_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0055186 name: RBTN1_HUMAN def: "Rhombotin-1" [UniProtKB:P25800] synonym: "Cysteine-rich protein TTG-1" EXACT [UniProtKB:P25800] synonym: "LIM domain only protein 1" EXACT [UniProtKB:P25800] synonym: "T-cell translocation protein 1" EXACT [UniProtKB:P25800] xref: EMBL:AAA36819.1 xref: EMBL:AAH69673.1 xref: EMBL:AAH69752.1 xref: EMBL:AAH69793.1 xref: EMBL:AAH96056.1 xref: EMBL:AAH96057.1 xref: EMBL:CAC14587.1 xref: UniProtKB:P25800 xref: UniProtKB:Q4VBC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019651 ! LMO1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055187 name: NPY1R_HUMAN def: "Neuropeptide Y receptor type 1" [UniProtKB:P25929] synonym: "NPY1-R" EXACT [UniProtKB:P25929] xref: EMBL:AAA59920.1 xref: EMBL:AAA59947.1 xref: EMBL:AAA73215.1 xref: EMBL:AAH36657.1 xref: EMBL:AAH71720.1 xref: EMBL:AAS55647.1 xref: UniProtKB:P25929 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018842 ! NPY1R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000156 ! peptide YY receptor activity relationship: has_function CCO:F0000157 ! pancreatic polypeptide receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017325 ! lsm7-npy1r physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway [Term] id: CCO:B0055188 name: TNR5_HUMAN def: "Tumor necrosis factor receptor superfamily member 5 precursor" [UniProtKB:P25942] synonym: "B-cell surface antigen CD40" EXACT [UniProtKB:P25942] synonym: "Bp50" EXACT [UniProtKB:P25942] synonym: "CD40 antigen" EXACT [UniProtKB:P25942] synonym: "CD40L receptor" EXACT [UniProtKB:P25942] synonym: "CDw40" EXACT [UniProtKB:P25942] xref: EMBL:AAH12419.1 xref: EMBL:AAO43990.1 xref: EMBL:AAR84238.1 xref: EMBL:AAV38704.1 xref: EMBL:ABK41937.1 xref: EMBL:BAD96616.1 xref: EMBL:CAA43045.1 xref: EMBL:CAC17670.1 xref: EMBL:CAC29424.1 xref: EMBL:CAI42973.1 xref: EMBL:EAW75758.1 xref: EMBL:EAW75760.1 xref: UniProtKB:P25942 xref: UniProtKB:Q53GN5 xref: UniProtKB:Q5JY15 xref: UniProtKB:Q5U007 xref: UniProtKB:Q7M4Q8 xref: UniProtKB:Q86YK5 xref: UniProtKB:Q9BYU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020320 ! CD40_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016270 ! cd40-traf3-2 physical interaction relationship: participates_in CCO:I0017704 ! cd40-traf3-1 physical interaction relationship: participates_in CCO:I0018707 ! cd40-traf6-2 direct interaction relationship: participates_in CCO:I0019495 ! cd40-traf3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002040 ! B cell proliferation relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055189 name: ITA3_HUMAN def: "Integrin alpha-3 precursor" [UniProtKB:P26006] synonym: "CD49 antigen-like family member C" EXACT [UniProtKB:P26006] synonym: "CD49c antigen" EXACT [UniProtKB:P26006] synonym: "FRP-2" EXACT [UniProtKB:P26006] synonym: "Galactoprotein B3" EXACT [UniProtKB:P26006] synonym: "GAPB3" EXACT [UniProtKB:P26006] synonym: "VLA-3 alpha chain" EXACT [UniProtKB:P26006] xref: EMBL:AAA36120.1 xref: EMBL:AAI50191.1 xref: EMBL:BAA00845.1 xref: EMBL:BAF82650.1 xref: EMBL:EAW94645.1 xref: UniProtKB:A7E246 xref: UniProtKB:P26006 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018333 ! ITGA3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0055190 name: PTX3_HUMAN def: "Pentraxin-related protein PTX3 precursor" [UniProtKB:P26022] synonym: "Pentaxin-related protein PTX3" EXACT [UniProtKB:P26022] synonym: "TSG-14" EXACT [UniProtKB:P26022] synonym: "Tumor necrosis factor-inducible gene 14 protein" EXACT [UniProtKB:P26022] xref: EMBL:AAA61234.1 xref: EMBL:AAH39733.1 xref: EMBL:ABA64467.1 xref: EMBL:CAA44778.1 xref: EMBL:CAA45158.1 xref: EMBL:EAW78708.1 xref: UniProtKB:P26022 xref: UniProtKB:Q38M82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019556 ! PTX3_human relationship: has_function CCO:F0000240 ! zymosan binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis [Term] id: CCO:B0055191 name: AMFR1_HUMAN def: "Autocrine motility factor receptor, isoform 1 precursor" [UniProtKB:P26442] synonym: "AMF receptor, isoform 1" EXACT [UniProtKB:P26442] xref: EMBL:AAA36671.1 xref: EMBL:AAA79362.1 xref: UniProtKB:P26442 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016958 ! AMFR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065612 ! AMFR1_HUMAN-Phosphoserine194 [Term] id: CCO:B0055192 name: NKG2D_HUMAN def: "NKG2-D type II integral membrane protein" [UniProtKB:P26718] synonym: "CD314 antigen" EXACT [UniProtKB:P26718] synonym: "Killer cell lectin-like receptor subfamily K member 1" EXACT [UniProtKB:P26718] synonym: "NK cell receptor D" EXACT [UniProtKB:P26718] synonym: "NKG2-D-activating NK receptor" EXACT [UniProtKB:P26718] xref: EMBL:AAF86973.1 xref: EMBL:AAF86974.1 xref: EMBL:AAH39836.1 xref: EMBL:AAL65233.1 xref: EMBL:CAA04925.1 xref: EMBL:CAA38652.1 xref: UniProtKB:P26718 xref: UniProtKB:Q9NR41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018791 ! KLRK1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0004978 ! MHC class Ib receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015902 ! raet1g-klrk1-1 physical interaction relationship: participates_in CCO:I0018706 ! klrk1-ulbp3-1 direct interaction relationship: participates_in CCO:P0000534 ! stimulatory C-type lectin receptor signaling pathway relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0002637 ! positive regulation of natural killer cell mediated cytotoxicity [Term] id: CCO:B0055193 name: CD27_HUMAN def: "CD27 antigen precursor" [UniProtKB:P26842] synonym: "CD27 antigen" EXACT [UniProtKB:P26842] synonym: "CD27L receptor" EXACT [UniProtKB:P26842] synonym: "T-cell activation antigen CD27" EXACT [UniProtKB:P26842] synonym: "T14" EXACT [UniProtKB:P26842] synonym: "Tumor necrosis factor receptor superfamily member 7" EXACT [UniProtKB:P26842] xref: EMBL:AAA58411.1 xref: EMBL:AAH12160.1 xref: EMBL:AAR84239.1 xref: UniProtKB:P26842 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017294 ! CD27_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005787 ! caspase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018025 ! cd27-siva physical interaction relationship: participates_in CCO:I0018026 ! cd27-siva-1 physical interaction relationship: participates_in CCO:I0018044 ! cd27-traf2-1 physical interaction relationship: participates_in CCO:I0019496 ! cd27-traf2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000825 ! release of cytoplasmic sequestered NF-kappaB relationship: participates_in CCO:P0002393 ! positive regulation of B cell differentiation relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: transforms_into CCO:B0064144 ! CD27_HUMAN-Phosphoserine219 [Term] id: CCO:B0055194 name: APEX1_HUMAN def: "DNA-(apurinic or apyrimidinic site) lyase" [UniProtKB:P27695] synonym: "AP endonuclease 1" EXACT [UniProtKB:P27695] synonym: "APEN" EXACT [UniProtKB:P27695] synonym: "APEX nuclease" EXACT [UniProtKB:P27695] synonym: "Apurinic-apyrimidinic endonuclease 1" EXACT [UniProtKB:P27695] synonym: "EC 4.2.99.18" EXACT [UniProtKB:P27695] synonym: "Protein REF-1" EXACT [UniProtKB:P27695] xref: EMBL:AAA58371.1 xref: EMBL:AAA58372.1 xref: EMBL:AAA58373.1 xref: EMBL:AAA58629.1 xref: EMBL:AAB22977.1 xref: EMBL:AAB50212.1 xref: EMBL:AAH02338.1 xref: EMBL:AAH04979.1 xref: EMBL:AAH08145.1 xref: EMBL:AAH19291.1 xref: EMBL:AAL86909.1 xref: EMBL:AAP35900.1 xref: EMBL:BAA02633.1 xref: EMBL:BAA14381.1 xref: EMBL:CAA42437.1 xref: EMBL:CAA46925.1 xref: UniProtKB:P27695 xref: UniProtKB:Q969L5 xref: UniProtKB:Q99775 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016986 ! APEX1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0000411 ! DNA-(apurinic or apyrimidinic site) lyase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000917 ! endodeoxyribonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0000924 ! phosphodiesterase I activity relationship: has_function CCO:F0001200 ! uracil DNA N-glycosylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001701 ! phosphoric diester hydrolase activity relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis relationship: transforms_into CCO:B0065690 ! APEX1_HUMAN-Phosphotyrosine262 [Term] id: CCO:B0055195 name: PDE4A_HUMAN def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4A" [UniProtKB:P27815] synonym: "DPDE2" EXACT [UniProtKB:P27815] synonym: "EC 3.1.4.17" EXACT [UniProtKB:P27815] synonym: "PDE46" EXACT [UniProtKB:P27815] xref: EMBL:AAA03588.1 xref: EMBL:AAA69697.1 xref: EMBL:AAA98540.1 xref: EMBL:AAB33798.1 xref: EMBL:AAC25679.1 xref: EMBL:AAC35012.1 xref: EMBL:AAC35013.1 xref: EMBL:AAC35014.1 xref: EMBL:AAC35015.1 xref: EMBL:AAC50458.1 xref: EMBL:AAC63832.1 xref: EMBL:AAH19864.1 xref: UniProtKB:O75522 xref: UniProtKB:O76092 xref: UniProtKB:P27815 xref: UniProtKB:Q16255 xref: UniProtKB:Q16691 xref: UniProtKB:Q8WUQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019338 ! PDE4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069171 ! PDE4A_HUMAN-Phosphoserine686 relationship: transforms_into CCO:B0069172 ! PDE4A_HUMAN-Phosphoserine688 [Term] id: CCO:B0055196 name: MAP4_HUMAN def: "Microtubule-associated protein 4" [UniProtKB:P27816] synonym: "MAP-4" EXACT [UniProtKB:P27816] xref: EMBL:AAA59553.1 xref: EMBL:AAA67361.1 xref: EMBL:AAH08715.1 xref: EMBL:AAH12794.1 xref: EMBL:AAH15149.1 xref: EMBL:BAB70795.1 xref: EMBL:BAC86099.1 xref: EMBL:BAD92614.1 xref: EMBL:CAH18346.1 xref: EMBL:EAW64839.1 xref: UniProtKB:P27816 xref: UniProtKB:Q13082 xref: UniProtKB:Q59FT2 xref: UniProtKB:Q68D74 xref: UniProtKB:Q6ZUW9 xref: UniProtKB:Q96A76 xref: UniProtKB:Q96NS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018567 ! MAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019989 ! eno2-map4 physical interaction relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: transforms_into CCO:B0067937 ! MAP4_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0067938 ! MAP4_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0067939 ! MAP4_HUMAN-Phosphothreonine96 relationship: transforms_into CCO:B0067940 ! MAP4_HUMAN-Phosphothreonine97 relationship: transforms_into CCO:B0067941 ! MAP4_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0067942 ! MAP4_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0067943 ! MAP4_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0067944 ! MAP4_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0067945 ! MAP4_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0067946 ! MAP4_HUMAN-Phosphothreonine282 relationship: transforms_into CCO:B0067947 ! MAP4_HUMAN-Phosphothreonine287 relationship: transforms_into CCO:B0067948 ! MAP4_HUMAN-Phosphothreonine380 relationship: transforms_into CCO:B0067949 ! MAP4_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0067950 ! MAP4_HUMAN-Phosphothreonine484 relationship: transforms_into CCO:B0067951 ! MAP4_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0067952 ! MAP4_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0067953 ! MAP4_HUMAN-Phosphothreonine521 relationship: transforms_into CCO:B0067954 ! MAP4_HUMAN-Phosphothreonine526 relationship: transforms_into CCO:B0067955 ! MAP4_HUMAN-Phosphothreonine571 relationship: transforms_into CCO:B0067956 ! MAP4_HUMAN-Phosphoserine609 relationship: transforms_into CCO:B0067957 ! MAP4_HUMAN-Phosphoserine624 relationship: transforms_into CCO:B0067958 ! MAP4_HUMAN-Phosphothreonine627 relationship: transforms_into CCO:B0067959 ! MAP4_HUMAN-Phosphoserine636 relationship: transforms_into CCO:B0067960 ! MAP4_HUMAN-Phosphoserine643 relationship: transforms_into CCO:B0067961 ! MAP4_HUMAN-Phosphoserine656 relationship: transforms_into CCO:B0067962 ! MAP4_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0067963 ! MAP4_HUMAN-Phosphoserine742 relationship: transforms_into CCO:B0067964 ! MAP4_HUMAN-Phosphoserine745 relationship: transforms_into CCO:B0067965 ! MAP4_HUMAN-Phosphoserine760 relationship: transforms_into CCO:B0067966 ! MAP4_HUMAN-Phosphoserine764 relationship: transforms_into CCO:B0067967 ! MAP4_HUMAN-Phosphoserine768 relationship: transforms_into CCO:B0067968 ! MAP4_HUMAN-Phosphoserine787 relationship: transforms_into CCO:B0067969 ! MAP4_HUMAN-Phosphoserine793 relationship: transforms_into CCO:B0067970 ! MAP4_HUMAN-Phosphothreonine811 relationship: transforms_into CCO:B0067971 ! MAP4_HUMAN-Phosphoserine825 relationship: transforms_into CCO:B0067972 ! MAP4_HUMAN-Phosphoserine827 relationship: transforms_into CCO:B0067973 ! MAP4_HUMAN-Phosphothreonine828 relationship: transforms_into CCO:B0067974 ! MAP4_HUMAN-Phosphothreonine874 relationship: transforms_into CCO:B0067975 ! MAP4_HUMAN-Phosphoserine899 relationship: transforms_into CCO:B0067976 ! MAP4_HUMAN-Phosphoserine915 relationship: transforms_into CCO:B0067977 ! MAP4_HUMAN-Phosphothreonine917 relationship: transforms_into CCO:B0067978 ! MAP4_HUMAN-Phosphothreonine925 relationship: transforms_into CCO:B0067979 ! MAP4_HUMAN-Phosphoserine928 relationship: transforms_into CCO:B0067980 ! MAP4_HUMAN-Phosphoserine1000 relationship: transforms_into CCO:B0067981 ! MAP4_HUMAN-Phosphotyrosine1001 relationship: transforms_into CCO:B0067982 ! MAP4_HUMAN-Phosphoserine1073 relationship: transforms_into CCO:B0067983 ! MAP4_HUMAN-Phosphoserine1151 [Term] id: CCO:B0055197 name: 5HT1B_HUMAN def: "5-hydroxytryptamine receptor 1B" [UniProtKB:P28222] synonym: "5-HT-1B" EXACT [UniProtKB:P28222] synonym: "5-HT-1D-beta" EXACT [UniProtKB:P28222] synonym: "5-HT1B" EXACT [UniProtKB:P28222] synonym: "S12" EXACT [UniProtKB:P28222] synonym: "Serotonin 1D beta receptor" EXACT [UniProtKB:P28222] synonym: "Serotonin receptor 1B" EXACT [UniProtKB:P28222] xref: EMBL:AAA36029.1 xref: EMBL:AAA36030.1 xref: EMBL:AAA58675.1 xref: EMBL:AAA60316.1 xref: EMBL:AAH69065.1 xref: EMBL:AAH96206.1 xref: EMBL:AAH96207.1 xref: EMBL:AAH96208.1 xref: EMBL:AAO67712.1 xref: EMBL:BAA01763.1 xref: EMBL:BAA94455.1 xref: EMBL:CAB51537.1 xref: UniProtKB:P28222 xref: UniProtKB:Q4VAY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016851 ! HTR1B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055198 name: 5HT2A_HUMAN def: "5-hydroxytryptamine receptor 2A" [UniProtKB:P28223] synonym: "5-HT-2" EXACT [UniProtKB:P28223] synonym: "5-HT-2A" EXACT [UniProtKB:P28223] synonym: "Serotonin receptor 2A" EXACT [UniProtKB:P28223] xref: EMBL:AAA58354.1 xref: EMBL:AAB22791.2 xref: EMBL:AAB24166.2 xref: EMBL:AAB31320.1 xref: EMBL:AAH69356.1 xref: EMBL:AAH69576.1 xref: EMBL:AAH74848.1 xref: EMBL:AAH74849.1 xref: EMBL:AAH96839.1 xref: EMBL:AAM21129.1 xref: EMBL:CAA40963.1 xref: EMBL:CAI12227.1 xref: EMBL:CAI16877.1 xref: UniProtKB:P28223 xref: UniProtKB:Q5T8C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016854 ! HTR2A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001005 ! dendrite relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000743 ! serotonin receptor, phospholipase C activating pathway relationship: participates_in CCO:P0000745 ! serotonin receptor signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001078 ! regulation of dopamine secretion relationship: participates_in CCO:P0003170 ! negative regulation of synaptic transmission, glutamatergic [Term] id: CCO:B0055199 name: LYOX_HUMAN def: "Protein-lysine 6-oxidase precursor" [UniProtKB:P28300] synonym: "EC 1.4.3.13" EXACT [UniProtKB:P28300] synonym: "Lysyl oxidase" EXACT [UniProtKB:P28300] xref: EMBL:AAA16870.1 xref: EMBL:AAA59525.1 xref: EMBL:AAA59541.1 xref: EMBL:AAB21243.1 xref: EMBL:AAB23549.1 xref: EMBL:AAD02130.1 xref: EMBL:AAH74820.1 xref: EMBL:AAH74872.1 xref: EMBL:AAH89436.1 xref: UniProtKB:P28300 xref: UniProtKB:Q5FWF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018536 ! LOX_human relationship: has_function CCO:F0001085 ! protein-lysine 6-oxidase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000205 ! collagen relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0067802 ! LYOX_HUMAN-2',4',5'-topaquinone355 [Term] id: CCO:B0055200 name: ELK4_HUMAN def: "ETS domain-containing protein Elk-4" [UniProtKB:P28324] synonym: "SAP-1" EXACT [UniProtKB:P28324] synonym: "Serum response factor accessory protein 1" EXACT [UniProtKB:P28324] xref: EMBL:AAA03631.1 xref: EMBL:AAA03632.1 xref: UniProtKB:P28323 xref: UniProtKB:P28324 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017687 ! ELK4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055201 name: NMBR_HUMAN def: "Neuromedin-B receptor" [UniProtKB:P28336] synonym: "Neuromedin-B-preferring bombesin receptor" EXACT [UniProtKB:P28336] synonym: "NMB-R" EXACT [UniProtKB:P28336] xref: EMBL:AAA59939.1 xref: EMBL:CAH70473.1 xref: EMBL:EAW47886.1 xref: UniProtKB:P28336 xref: UniProtKB:Q5VUK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018806 ! NMBR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001288 ! bombesin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0055202 name: HXD10_HUMAN def: "Homeobox protein Hox-D10" [UniProtKB:P28358] synonym: "Hox-4D" EXACT [UniProtKB:P28358] synonym: "Hox-4E" EXACT [UniProtKB:P28358] xref: EMBL:AAH69619.1 xref: EMBL:AAH74760.1 xref: EMBL:CAA42017.1 xref: UniProtKB:P28358 xref: UniProtKB:Q6NT10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018189 ! HOXD10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055203 name: MSX1_HUMAN def: "Homeobox protein MSX-1" [UniProtKB:P28360] synonym: "Hox-7" EXACT [UniProtKB:P28360] synonym: "Msh homeobox 1-like protein" EXACT [UniProtKB:P28360] xref: EMBL:AAA52683.1 xref: EMBL:AAA58665.1 xref: EMBL:AAH21285.4 xref: EMBL:AAH67353.1 xref: EMBL:AAL17870.1 xref: UniProtKB:P28360 xref: UniProtKB:Q96NY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018666 ! MSX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055204 name: SMCA1_HUMAN def: "Probable global transcription activator SNF2L1" [UniProtKB:P28370] synonym: "ATP-dependent helicase SMARCA1" EXACT [UniProtKB:P28370] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P28370] synonym: "Nucleosome-remodeling factor subunit SNF2L" EXACT [UniProtKB:P28370] synonym: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1" EXACT [UniProtKB:P28370] xref: EMBL:AAA80559.1 xref: EMBL:AAA80560.1 xref: EMBL:AAI17448.1 xref: EMBL:CAI42612.1 xref: EMBL:CAI42613.1 xref: EMBL:CAI42682.1 xref: EMBL:CAI42683.1 xref: UniProtKB:P28370 xref: UniProtKB:Q5JV41 xref: UniProtKB:Q5JV42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019948 ! SMARCA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: transforms_into CCO:B0070619 ! SMCA1_HUMAN-Phosphotyrosine954 [Term] id: CCO:B0055205 name: 5HT1E_HUMAN def: "5-hydroxytryptamine receptor 1E" [UniProtKB:P28566] synonym: "5-HT-1E" EXACT [UniProtKB:P28566] synonym: "5-HT1E" EXACT [UniProtKB:P28566] synonym: "S31" EXACT [UniProtKB:P28566] synonym: "Serotonin receptor 1E" EXACT [UniProtKB:P28566] xref: EMBL:AAA58353.1 xref: EMBL:AAA58355.1 xref: EMBL:AAH69751.1 xref: EMBL:AAM21127.1 xref: EMBL:BAA94458.1 xref: EMBL:CAA77558.1 xref: EMBL:CAC10582.1 xref: UniProtKB:P28566 xref: UniProtKB:Q9P1Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016852 ! HTR1E_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055206 name: MZF1_HUMAN def: "Myeloid zinc finger 1" [UniProtKB:P28698] synonym: "MZF-1" EXACT [UniProtKB:P28698] synonym: "Zinc finger and SCAN domain-containing protein 6" EXACT [UniProtKB:P28698] synonym: "Zinc finger protein 42" EXACT [UniProtKB:P28698] xref: EMBL:AAA59898.1 xref: EMBL:AAD55809.1 xref: EMBL:AAD55810.1 xref: EMBL:AAF80465.1 xref: EMBL:AAF80466.1 xref: UniProtKB:P28698 xref: UniProtKB:Q9NRY0 xref: UniProtKB:Q9UBW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018706 ! MZF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068427 ! MZF1_HUMAN-Phosphoserine394 [Term] id: CCO:B0055207 name: CD38_HUMAN def: "ADP-ribosyl cyclase 1" [UniProtKB:P28907] synonym: "cADPr hydrolase 1" EXACT [UniProtKB:P28907] synonym: "CD38 antigen" EXACT [UniProtKB:P28907] synonym: "Cyclic ADP-ribose hydrolase 1" EXACT [UniProtKB:P28907] synonym: "EC 3.2.2.5" EXACT [UniProtKB:P28907] synonym: "T10" EXACT [UniProtKB:P28907] xref: EMBL:AAA68482.1 xref: EMBL:AAH07964.1 xref: EMBL:BAA18964.1 xref: EMBL:BAA18965.1 xref: EMBL:BAA18966.1 xref: UniProtKB:O00121 xref: UniProtKB:O00122 xref: UniProtKB:P28907 xref: UniProtKB:Q96HY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017298 ! CD38_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000446 ! NAD+ nucleosidase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals [Term] id: CCO:B0055208 name: T2EA_HUMAN def: "General transcription factor IIE subunit 1" [UniProtKB:P29083] synonym: "General transcription factor IIE 56 kDa subunit" EXACT [UniProtKB:P29083] synonym: "TFIIE-alpha" EXACT [UniProtKB:P29083] synonym: "Transcription initiation factor IIE subunit alpha" EXACT [UniProtKB:P29083] xref: EMBL:AAB20413.1 xref: EMBL:CAA45068.1 xref: UniProtKB:P29083 xref: UniProtKB:Q16103 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020090 ! GTF2E1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071070 ! T2EA_HUMAN-Phosphoserine268 [Term] id: CCO:B0055209 name: T2EB_HUMAN def: "Transcription initiation factor IIE subunit beta" [UniProtKB:P29084] synonym: "General transcription factor IIE subunit 2" EXACT [UniProtKB:P29084] synonym: "TFIIE-beta" EXACT [UniProtKB:P29084] xref: EMBL:AAB20414.1 xref: EMBL:AAG39077.1 xref: EMBL:AAH30572.1 xref: EMBL:CAA45069.1 xref: UniProtKB:P29084 xref: UniProtKB:Q9H2B9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020091 ! GTF2E2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000277 ! transcription factor TFIIE complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055210 name: AA2AR_HUMAN def: "Adenosine receptor A2a" [UniProtKB:P29274] xref: EMBL:AAA58356.1 xref: EMBL:AAA83270.1 xref: EMBL:AAB23956.1 xref: EMBL:AAH13780.1 xref: EMBL:AAN01273.1 xref: EMBL:AAP35645.1 xref: EMBL:CAA48504.1 xref: EMBL:CAG30253.1 xref: UniProtKB:P29274 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016862 ! ADORA2A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000164 ! adenosine receptor activity, G-protein coupled relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000517 ! adenosine receptor signaling pathway relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0001568 ! positive regulation of synaptic transmission, GABAergic [Term] id: CCO:B0055211 name: AA2BR_HUMAN def: "Adenosine receptor A2b" [UniProtKB:P29275] xref: EMBL:AAA51598.1 xref: EMBL:AAH25722.1 xref: EMBL:AAN01274.1 xref: EMBL:CAA48505.1 xref: UniProtKB:P29275 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016863 ! ADORA2B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000164 ! adenosine receptor activity, G-protein coupled relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000772 ! JNK cascade [Term] id: CCO:B0055212 name: RABP2_HUMAN def: "Cellular retinoic acid-binding protein 2" [UniProtKB:P29373] synonym: "Cellular retinoic acid-binding protein II" EXACT [UniProtKB:P29373] synonym: "CRABP-II" EXACT [UniProtKB:P29373] xref: EMBL:AAA52068.1 xref: EMBL:AAA58430.1 xref: EMBL:AAH01109.1 xref: EMBL:AAV38630.1 xref: EMBL:CAG29353.1 xref: EMBL:CAI16339.1 xref: UniProtKB:P29373 xref: UniProtKB:Q6ICN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008665 ! CRABP2_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001639 ! retinoid binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003468 ! retinal binding relationship: has_function CCO:F0004190 ! retinol binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055213 name: JAD1A_HUMAN def: "Histone demethylase JARID1A" [UniProtKB:P29375] synonym: "EC 1.14.11.-" EXACT [UniProtKB:P29375] synonym: "Jumonji/ARID domain-containing protein 1A" EXACT [UniProtKB:P29375] synonym: "RBBP-2" EXACT [UniProtKB:P29375] synonym: "Retinoblastoma-binding protein 2" EXACT [UniProtKB:P29375] xref: EMBL:AAB28544.1 xref: EMBL:AAH48307.1 xref: EMBL:AAH53893.1 xref: EMBL:AAI10917.1 xref: EMBL:BAE06081.1 xref: UniProtKB:P29375 xref: UniProtKB:Q4LE72 xref: UniProtKB:Q86XZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018352 ! JARID1A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067178 ! JAD1A_HUMAN-Phosphoserine1111 relationship: transforms_into CCO:B0067179 ! JAD1A_HUMAN-Phosphoserine1331 relationship: transforms_into CCO:B0067180 ! JAD1A_HUMAN-Phosphoserine1598 relationship: transforms_into CCO:B0067181 ! JAD1A_HUMAN-Phosphoserine1603 relationship: transforms_into CCO:B0067182 ! JAD1A_HUMAN-Phosphoserine1666 [Term] id: CCO:B0055214 name: LTK_HUMAN def: "Leukocyte tyrosine kinase receptor precursor" [UniProtKB:P29376] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P29376] synonym: "Protein tyrosine kinase 1" EXACT [UniProtKB:P29376] xref: EMBL:BAA03679.1 xref: EMBL:CAA36460.1 xref: EMBL:CAA43113.1 xref: UniProtKB:P29376 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008441 ! LTK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0067794 ! LTK_HUMAN-Phosphotyrosine672 relationship: transforms_into CCO:B0067795 ! LTK_HUMAN-Phosphotyrosine676 relationship: transforms_into CCO:B0067796 ! LTK_HUMAN-Phosphotyrosine677 [Term] id: CCO:B0055215 name: NOS3_HUMAN def: "Nitric oxide synthase, endothelial" [UniProtKB:P29474] synonym: "cNOS" EXACT [UniProtKB:P29474] synonym: "Constitutive NOS" EXACT [UniProtKB:P29474] synonym: "EC 1.14.13.39" EXACT [UniProtKB:P29474] synonym: "EC-NOS" EXACT [UniProtKB:P29474] synonym: "Endothelial NOS" EXACT [UniProtKB:P29474] synonym: "eNOS" EXACT [UniProtKB:P29474] synonym: "NOS type III" EXACT [UniProtKB:P29474] synonym: "NOSIII" EXACT [UniProtKB:P29474] xref: EMBL:AAA36364.1 xref: EMBL:AAA36365.1 xref: EMBL:AAA36372.1 xref: EMBL:AAA36373.1 xref: EMBL:AAA36374.1 xref: EMBL:AAD14336.1 xref: EMBL:AAH69465.1 xref: EMBL:AAM74944.1 xref: EMBL:BAA05652.1 xref: EMBL:CAA53950.1 xref: UniProtKB:P29474 xref: UniProtKB:Q13662 xref: UniProtKB:Q14251 xref: UniProtKB:Q14434 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018819 ! NOS3_human relationship: has_function CCO:F0000914 ! nitric-oxide synthase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0002446 ! FMN binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_function CCO:F0007987 ! NADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001484 ! lipopolysaccharide-mediated signaling pathway relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation relationship: transforms_into CCO:B0068791 ! NOS3_HUMAN-Phosphotyrosine81 relationship: transforms_into CCO:B0068792 ! NOS3_HUMAN-Phosphothreonine495 relationship: transforms_into CCO:B0068793 ! NOS3_HUMAN-Phosphoserine633 relationship: transforms_into CCO:B0068794 ! NOS3_HUMAN-Phosphothreonine1175 relationship: transforms_into CCO:B0068795 ! NOS3_HUMAN-Phosphoserine1177 [Term] id: CCO:B0055216 name: PRDX3_HUMAN def: "Thioredoxin-dependent peroxide reductase, mitochondrial precursor" [UniProtKB:P30048] synonym: "Antioxidant protein 1" EXACT [UniProtKB:P30048] synonym: "AOP-1" EXACT [UniProtKB:P30048] synonym: "EC 1.11.1.15" EXACT [UniProtKB:P30048] synonym: "HBC189" EXACT [UniProtKB:P30048] synonym: "Peroxiredoxin-3" EXACT [UniProtKB:P30048] synonym: "Protein MER5 homolog" EXACT [UniProtKB:P30048] synonym: "PRX III" EXACT [UniProtKB:P30048] xref: EMBL:AAH02685.1 xref: EMBL:AAH07062.1 xref: EMBL:AAH08435.1 xref: EMBL:AAH09601.1 xref: EMBL:AAH21691.1 xref: EMBL:AAH22373.1 xref: EMBL:AAH59169.1 xref: EMBL:AAI11398.1 xref: EMBL:AAV38810.1 xref: EMBL:ABB84468.1 xref: EMBL:BAA08389.1 xref: EMBL:CAG29340.1 xref: EMBL:CAI15802.1 xref: UniProtKB:P30048 xref: UniProtKB:P35690 xref: UniProtKB:Q0D2H1 xref: UniProtKB:Q13776 xref: UniProtKB:Q5T5V2 xref: UniProtKB:Q96HK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019503 ! PRDX3_human relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0002130 ! alkyl hydroperoxide reductase activity relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0008212 ! peroxiredoxin activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000547 ! IkappaB kinase complex relationship: participates_in CCO:I0015410 ! magea11-prdx3 physical interaction relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0055217 name: FCERG_HUMAN def: "High affinity immunoglobulin epsilon receptor subunit gamma precursor" [UniProtKB:P30273] synonym: "Fc-epsilon RI-gamma" EXACT [UniProtKB:P30273] synonym: "FceRI gamma" EXACT [UniProtKB:P30273] synonym: "IgE Fc receptor subunit gamma" EXACT [UniProtKB:P30273] xref: EMBL:AAA35828.1 xref: EMBL:CAH72149.1 xref: UniProtKB:P30273 xref: UniProtKB:Q5VTW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017768 ! FCER1G_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016109 ! syk-fcer1g-1 physical interaction relationship: participates_in CCO:I0018837 ! gpiv-fcer1g-1 physical interaction relationship: participates_in CCO:P0000549 ! Fc receptor mediated stimulatory signaling pathway relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001757 ! negative regulation of mast cell apoptosis relationship: participates_in CCO:P0002182 ! positive regulation of mast cell degranulation relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis relationship: transforms_into CCO:B0066148 ! FCERG_HUMAN-Phosphotyrosine65 relationship: transforms_into CCO:B0066149 ! FCERG_HUMAN-Phosphotyrosine76 relationship: transforms_into CCO:B0066150 ! FCERG_HUMAN-Phosphothreonine78 [Term] id: CCO:B0055218 name: BKRB2_HUMAN def: "B2 bradykinin receptor" [UniProtKB:P30411] synonym: "B2R" EXACT [UniProtKB:P30411] synonym: "BK-2 receptor" EXACT [UniProtKB:P30411] xref: EMBL:AAB02793.1 xref: EMBL:AAB23467.1 xref: EMBL:AAB25765.1 xref: EMBL:AAH74894.1 xref: EMBL:AAH74895.1 xref: EMBL:AAK56376.1 xref: EMBL:AAP32297.1 xref: EMBL:CAA49360.1 xref: EMBL:CAA60108.1 xref: EMBL:CAA60109.1 xref: UniProtKB:P30411 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017163 ! BDKRB2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000256 ! protease binding relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001289 ! bradykinin receptor activity relationship: has_function CCO:F0004715 ! type 1 angiotensin receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055219 name: V2R_HUMAN def: "Vasopressin V2 receptor" [UniProtKB:P30518] synonym: "Antidiuretic hormone receptor" EXACT [UniProtKB:P30518] synonym: "AVPR V2" EXACT [UniProtKB:P30518] synonym: "Renal-type arginine vasopressin receptor" EXACT [UniProtKB:P30518] xref: EMBL:AAA03651.1 xref: EMBL:AAB86428.1 xref: EMBL:AAC09005.1 xref: EMBL:AAD16444.1 xref: EMBL:AAI01485.1 xref: EMBL:AAI12182.1 xref: EMBL:AAO92298.1 xref: EMBL:CAA77746.1 xref: UniProtKB:P30518 xref: UniProtKB:Q3MJD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020430 ! AVPR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001338 ! vasopressin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:B0055220 name: TSPO_HUMAN def: "Translocator protein" [UniProtKB:P30536] synonym: "Mitochondrial benzodiazepine receptor" EXACT [UniProtKB:P30536] synonym: "PBR" EXACT [UniProtKB:P30536] synonym: "Peripheral-type benzodiazepine receptor" EXACT [UniProtKB:P30536] synonym: "PKBS" EXACT [UniProtKB:P30536] xref: EMBL:AAA03652.1 xref: EMBL:AAA83252.1 xref: EMBL:AAH01110.1 xref: EMBL:AAQ75703.1 xref: EMBL:CAB55884.1 xref: UniProtKB:P30536 xref: UniProtKB:Q96TF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020376 ! TSPO_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001957 ! benzodiazepine receptor activity relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055221 name: AA1R_HUMAN def: "Adenosine receptor A1" [UniProtKB:P30542] xref: EMBL:AAA17544.1 xref: EMBL:AAB23388.1 xref: EMBL:AAB25533.2 xref: EMBL:AAH26340.1 xref: EMBL:AAN01272.1 xref: EMBL:AAV38657.1 xref: EMBL:BAA20433.1 xref: EMBL:BAF82617.1 xref: EMBL:CAA48503.1 xref: EMBL:CAG46549.1 xref: EMBL:EAW91465.1 xref: UniProtKB:A6NFY5 xref: UniProtKB:A6NGP4 xref: UniProtKB:A8K1L3 xref: UniProtKB:P30542 xref: UniProtKB:Q6FHK3 xref: UniProtKB:Q8TAM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016861 ! ADORA1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000164 ! adenosine receptor activity, G-protein coupled relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals [Term] id: CCO:B0055222 name: GRPR_HUMAN def: "Gastrin-releasing peptide receptor" [UniProtKB:P30550] synonym: "GRP-preferring bombesin receptor" EXACT [UniProtKB:P30550] synonym: "GRP-R" EXACT [UniProtKB:P30550] xref: EMBL:AAA88050.1 xref: EMBL:AAH74733.1 xref: EMBL:AAL96377.1 xref: UniProtKB:P30550 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018079 ! GRPR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001288 ! bombesin receptor activity relationship: has_function CCO:F0001980 ! peptide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0055223 name: AGTR1_HUMAN def: "Type-1 angiotensin II receptor" [UniProtKB:P30556] synonym: "AT1" EXACT [UniProtKB:P30556] synonym: "AT1AR" EXACT [UniProtKB:P30556] synonym: "AT1BR" EXACT [UniProtKB:P30556] xref: EMBL:AAA35535.1 xref: EMBL:AAA35569.1 xref: EMBL:AAA58370.1 xref: EMBL:AAB34644.1 xref: EMBL:AAF70464.1 xref: EMBL:AAO65968.1 xref: EMBL:BAA02968.1 xref: EMBL:CAA46621.1 xref: EMBL:CAA77513.1 xref: UniProtKB:P30556 xref: UniProtKB:Q13725 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016933 ! AGTR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000152 ! angiotensin type I receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_function CCO:F0001289 ! bradykinin receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_function CCO:F0004724 ! bradykinin receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0003100 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0055224 name: OXYR_HUMAN def: "Oxytocin receptor" [UniProtKB:P30559] synonym: "OT-R" EXACT [UniProtKB:P30559] xref: EMBL:AAQ91333.1 xref: EMBL:CAA46097.1 xref: EMBL:CAA56562.1 xref: UniProtKB:P30559 xref: UniProtKB:Q15071 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019256 ! OXTR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001328 ! oxytocin receptor activity relationship: has_function CCO:F0001338 ! vasopressin receptor activity relationship: has_function CCO:F0003529 ! peptide hormone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055225 name: GNA15_HUMAN def: "Guanine nucleotide-binding protein subunit alpha-15" [UniProtKB:P30679] synonym: "G alpha-15" EXACT [UniProtKB:P30679] synonym: "G alpha-16" EXACT [UniProtKB:P30679] synonym: "G-protein subunit alpha-15" EXACT [UniProtKB:P30679] synonym: "G-protein subunit alpha-16" EXACT [UniProtKB:P30679] synonym: "Guanine nucleotide-binding protein subunit alpha-16" EXACT [UniProtKB:P30679] xref: EMBL:AAA35860.1 xref: EMBL:AAC25612.1 xref: EMBL:AAC25616.1 xref: EMBL:AAH13585.1 xref: EMBL:AAM12618.1 xref: UniProtKB:O75247 xref: UniProtKB:P30679 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017942 ! GNA15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0000742 ! muscarinic acetylcholine receptor, phospholipase C activating pathway relationship: transforms_into CCO:B0066484 ! GNA15_HUMAN-ADP-ribosylarginine186 [Term] id: CCO:B0055226 name: 5HT1F_HUMAN def: "5-hydroxytryptamine receptor 1F" [UniProtKB:P30939] synonym: "5-HT-1F" EXACT [UniProtKB:P30939] synonym: "Serotonin receptor 1F" EXACT [UniProtKB:P30939] xref: EMBL:AAA36605.1 xref: EMBL:AAA36646.1 xref: EMBL:AAH69125.1 xref: EMBL:AAM21128.1 xref: UniProtKB:P30939 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016853 ! HTR1F_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055227 name: OR1E1_HUMAN def: "Olfactory receptor 1E1" [UniProtKB:P30953] synonym: "Olfactory receptor 13-66" EXACT [UniProtKB:P30953] synonym: "Olfactory receptor 17-2/17-32" EXACT [UniProtKB:P30953] synonym: "Olfactory receptor 5-85" EXACT [UniProtKB:P30953] synonym: "Olfactory receptor OR17-18" EXACT [UniProtKB:P30953] synonym: "Olfactory receptor-like protein HGMP07I" EXACT [UniProtKB:P30953] synonym: "OR13-66" EXACT [UniProtKB:P30953] synonym: "OR17-2" EXACT [UniProtKB:P30953] synonym: "OR17-32" EXACT [UniProtKB:P30953] synonym: "OR5-85" EXACT [UniProtKB:P30953] xref: EMBL:AAA17447.1 xref: EMBL:AAA18346.1 xref: EMBL:AAC39613.1 xref: EMBL:AAC39629.1 xref: EMBL:AAD00276.1 xref: EMBL:AAD17495.1 xref: EMBL:AAF03261.1 xref: EMBL:AAF37309.1 xref: EMBL:AAK95035.1 xref: EMBL:CAA46127.1 xref: EMBL:DAA04751.1 xref: UniProtKB:O43884 xref: UniProtKB:P30953 xref: UniProtKB:P47882 xref: UniProtKB:P47885 xref: UniProtKB:Q6IFA9 xref: UniProtKB:Q9UBJ1 xref: UniProtKB:Q9UM60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019062 ! OR1E1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055228 name: O10J1_HUMAN def: "Olfactory receptor 10J1" [UniProtKB:P30954] synonym: "Olfactory receptor OR1-26" EXACT [UniProtKB:P30954] synonym: "Olfactory receptor-like protein HGMP07J" EXACT [UniProtKB:P30954] xref: EMBL:AAH69150.1 xref: EMBL:AAI12291.1 xref: EMBL:AAK95072.1 xref: EMBL:CAA46128.1 xref: EMBL:DAA04925.1 xref: UniProtKB:P30954 xref: UniProtKB:Q2M1M8 xref: UniProtKB:Q6IET5 xref: UniProtKB:Q96R56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018919 ! OR10J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055229 name: GNRHR_HUMAN def: "Gonadotropin-releasing hormone receptor" [UniProtKB:P30968] synonym: "GnRH receptor" EXACT [UniProtKB:P30968] synonym: "GnRH-R" EXACT [UniProtKB:P30968] xref: EMBL:AAA35917.1 xref: EMBL:AAA35918.1 xref: EMBL:AAB26287.1 xref: EMBL:AAB33884.1 xref: EMBL:AAB71348.1 xref: EMBL:AAI13547.1 xref: EMBL:AAR92228.1 xref: EMBL:CAB03541.1 xref: EMBL:CAB17082.1 xref: UniProtKB:O75793 xref: UniProtKB:P30968 xref: UniProtKB:Q14D13 xref: UniProtKB:Q92644 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017947 ! GNRHR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001309 ! gonadotropin-releasing hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055230 name: CALCR_HUMAN def: "Calcitonin receptor precursor" [UniProtKB:P30988] synonym: "CT-R" EXACT [UniProtKB:P30988] xref: EMBL:AAA35640.1 xref: EMBL:AAB83945.1 xref: EMBL:AAC50300.1 xref: EMBL:AAC50301.1 xref: EMBL:AAD14268.1 xref: EMBL:AAH69611.1 xref: EMBL:AAH75028.2 xref: EMBL:AAR06949.1 xref: EMBL:BAA86928.1 xref: EMBL:BAA86929.1 xref: EMBL:CAA49541.1 xref: EMBL:CAA57849.1 xref: UniProtKB:O14585 xref: UniProtKB:P30988 xref: UniProtKB:Q13941 xref: UniProtKB:Q6DJU8 xref: UniProtKB:Q6T712 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017217 ! CALCR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001290 ! calcitonin receptor activity relationship: has_function CCO:F0005043 ! calcitonin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway [Term] id: CCO:B0055231 name: NTR1_HUMAN def: "Neurotensin receptor type 1" [UniProtKB:P30989] synonym: "High-affinity levocabastine-insensitive neurotensin receptor" EXACT [UniProtKB:P30989] synonym: "NT-R-1" EXACT [UniProtKB:P30989] synonym: "NTRH" EXACT [UniProtKB:P30989] xref: EMBL:AAR07901.1 xref: EMBL:CAA49675.1 xref: EMBL:CAC12747.2 xref: EMBL:CAC14923.2 xref: UniProtKB:P30989 xref: UniProtKB:Q9H4H1 xref: UniProtKB:Q9H4T5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018883 ! NTSR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003173 ! neurotensin receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055232 name: NEUT_HUMAN def: "Neurotensin/neuromedin N precursor" [UniProtKB:P30990] xref: EMBL:AAB23934.1 xref: EMBL:AAB50564.1 xref: EMBL:AAH10918.1 xref: UniProtKB:P30990 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018760 ! NTS_human relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055233 name: GDIA_HUMAN def: "Rab GDP dissociation inhibitor alpha" [UniProtKB:P31150] synonym: "GDI-1" EXACT [UniProtKB:P31150] synonym: "Guanosine diphosphate dissociation inhibitor 1" EXACT [UniProtKB:P31150] synonym: "Oligophrenin-2" EXACT [UniProtKB:P31150] synonym: "Protein XAP-4" EXACT [UniProtKB:P31150] synonym: "Rab GDI alpha" EXACT [UniProtKB:P31150] xref: EMBL:AAA21558.1 xref: EMBL:AAA92648.1 xref: EMBL:AAC15851.1 xref: EMBL:AAH00317.1 xref: EMBL:AAH12201.1 xref: EMBL:AAK92482.1 xref: EMBL:BAA08078.1 xref: EMBL:BAC80330.1 xref: EMBL:BAC80331.1 xref: EMBL:BAC80332.1 xref: EMBL:BAC80333.1 xref: EMBL:BAC80334.1 xref: EMBL:BAC80335.1 xref: EMBL:BAC80336.1 xref: EMBL:BAC80337.1 xref: EMBL:BAC80338.1 xref: EMBL:BAC80339.1 xref: EMBL:BAC80340.1 xref: EMBL:BAC80341.1 xref: EMBL:BAC80342.1 xref: EMBL:BAC80343.1 xref: EMBL:BAC80344.1 xref: EMBL:BAC80345.1 xref: EMBL:BAC80346.1 xref: EMBL:BAC80347.1 xref: EMBL:BAC80348.1 xref: EMBL:BAC80349.1 xref: EMBL:BAC80360.1 xref: EMBL:BAC80361.1 xref: EMBL:BAC80362.1 xref: EMBL:BAC80363.1 xref: EMBL:BAC80364.1 xref: EMBL:BAC80365.1 xref: EMBL:BAC80366.1 xref: EMBL:BAC80367.1 xref: EMBL:BAC80368.1 xref: EMBL:BAC80369.1 xref: EMBL:BAC80370.1 xref: EMBL:BAC80371.1 xref: EMBL:BAC80372.1 xref: EMBL:BAC80373.1 xref: EMBL:BAC80374.1 xref: EMBL:BAC80375.1 xref: EMBL:BAC80376.1 xref: EMBL:BAC80377.1 xref: EMBL:BAC80378.1 xref: EMBL:BAC80379.1 xref: EMBL:BAC80390.1 xref: EMBL:BAC80391.1 xref: EMBL:BAC80392.1 xref: EMBL:BAC80393.1 xref: EMBL:BAC80394.1 xref: EMBL:BAC80395.1 xref: EMBL:BAC80396.1 xref: EMBL:BAC80397.1 xref: EMBL:BAC80398.1 xref: EMBL:BAC80399.1 xref: EMBL:BAC80400.1 xref: EMBL:BAC80401.1 xref: EMBL:BAC80402.1 xref: EMBL:BAC80403.1 xref: EMBL:BAC80404.1 xref: EMBL:BAC80405.1 xref: EMBL:BAC80406.1 xref: EMBL:BAC80407.1 xref: EMBL:BAC80408.1 xref: EMBL:BAC80409.1 xref: EMBL:BAC80420.1 xref: EMBL:BAC80421.1 xref: EMBL:BAC80422.1 xref: EMBL:BAC80423.1 xref: EMBL:BAC80424.1 xref: EMBL:BAC80425.1 xref: EMBL:BAC80426.1 xref: EMBL:BAC80427.1 xref: EMBL:BAC80428.1 xref: EMBL:BAC80429.1 xref: EMBL:BAC80430.1 xref: EMBL:BAC80431.1 xref: EMBL:BAC80432.1 xref: EMBL:BAC80433.1 xref: EMBL:BAC80434.1 xref: EMBL:BAC80435.1 xref: EMBL:BAC80436.1 xref: EMBL:BAC80437.1 xref: EMBL:BAC80438.1 xref: EMBL:BAC80439.1 xref: EMBL:CAA55908.1 xref: EMBL:CAA55909.1 xref: UniProtKB:P31150 xref: UniProtKB:P50394 xref: UniProtKB:Q7Z2G6 xref: UniProtKB:Q7Z2G9 xref: UniProtKB:Q7Z2H5 xref: UniProtKB:Q7Z2I6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017908 ! GDI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018889 ! ubqln4-gdi1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0066434 ! GDIA_HUMAN-Phosphotyrosine333 relationship: transforms_into CCO:B0066435 ! GDIA_HUMAN-Phosphotyrosine339 [Term] id: CCO:B0055234 name: HXD3_HUMAN def: "Homeobox protein Hox-D3" [UniProtKB:P31249] synonym: "Hox-4A" EXACT [UniProtKB:P31249] xref: EMBL:AAH05124.1 xref: EMBL:AAH08789.1 xref: EMBL:BAA01891.1 xref: EMBL:CAA71102.1 xref: UniProtKB:P31249 xref: UniProtKB:Q99955 xref: UniProtKB:Q9BSC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018194 ! HOXD3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055235 name: HXA10_HUMAN def: "Homeobox protein Hox-A10" [UniProtKB:P31260] synonym: "Hox-1.8" EXACT [UniProtKB:P31260] synonym: "Hox-1H" EXACT [UniProtKB:P31260] synonym: "PL" EXACT [UniProtKB:P31260] xref: EMBL:AAA36006.1 xref: EMBL:AAB96917.1 xref: EMBL:AAD14030.1 xref: EMBL:AAD14031.1 xref: EMBL:AAH13971.1 xref: EMBL:AAH71843.1 xref: EMBL:CAB86198.1 xref: UniProtKB:O43370 xref: UniProtKB:O43605 xref: UniProtKB:P31260 xref: UniProtKB:Q15949 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018175 ! HOXA10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055236 name: HXA9_HUMAN def: "Homeobox protein Hox-A9" [UniProtKB:P31269] synonym: "Hox-1G" EXACT [UniProtKB:P31269] xref: EMBL:AAB40867.1 xref: EMBL:AAC50364.1 xref: EMBL:AAD08713.1 xref: EMBL:AAH06537.1 xref: EMBL:AAH10023.1 xref: EMBL:AAP35636.1 xref: UniProtKB:O43369 xref: UniProtKB:O43429 xref: UniProtKB:P31269 xref: UniProtKB:Q99820 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018181 ! HOXA9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015036 ! hoxa9-trip6 physical interaction relationship: participates_in CCO:I0015374 ! hoxa9-rbpms physical interaction relationship: participates_in CCO:I0015606 ! hoxa9-plscr1 physical interaction relationship: participates_in CCO:I0019408 ! hoxa9-trip6-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055237 name: HXA11_HUMAN def: "Homeobox protein Hox-A11" [UniProtKB:P31270] synonym: "Hox-1I" EXACT [UniProtKB:P31270] xref: EMBL:AAB94761.1 xref: EMBL:AAC80455.1 xref: EMBL:AAH40948.1 xref: UniProtKB:P31270 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018176 ! HOXA11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055238 name: HXA13_HUMAN def: "Homeobox protein Hox-A13" [UniProtKB:P31271] synonym: "Hox-1J" EXACT [UniProtKB:P31271] xref: EMBL:AAC50993.1 xref: UniProtKB:O43371 xref: UniProtKB:P31271 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018177 ! HOXA13_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055239 name: HXC9_HUMAN def: "Homeobox protein Hox-C9" [UniProtKB:P31274] synonym: "Hox-3B" EXACT [UniProtKB:P31274] xref: EMBL:AAG42151.1 xref: EMBL:AAH53894.1 xref: UniProtKB:P31274 xref: UniProtKB:Q9H1I0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018188 ! HOXC9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055240 name: HXC12_HUMAN def: "Homeobox protein Hox-C12" [UniProtKB:P31275] synonym: "Hox-3F" EXACT [UniProtKB:P31275] xref: EMBL:AAK16717.1 xref: UniProtKB:P31275 xref: UniProtKB:Q9BXJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018186 ! HOXC12_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055241 name: HXC13_HUMAN def: "Homeobox protein Hox-C13" [UniProtKB:P31276] synonym: "Hox-3G" EXACT [UniProtKB:P31276] xref: EMBL:AAF67760.1 xref: EMBL:AAF73439.1 xref: EMBL:AAH02754.1 xref: EMBL:AAH90850.1 xref: EMBL:AAP88910.1 xref: EMBL:BAB14786.1 xref: UniProtKB:P31276 xref: UniProtKB:Q5BL02 xref: UniProtKB:Q96J32 xref: UniProtKB:Q9NR24 xref: UniProtKB:Q9NYD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018187 ! HOXC13_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055242 name: HXD11_HUMAN def: "Homeobox protein Hox-D11" [UniProtKB:P31277] synonym: "Hox-4F" EXACT [UniProtKB:P31277] xref: EMBL:AAF79045.1 xref: UniProtKB:P31277 xref: UniProtKB:Q9NS02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018190 ! HOXD11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066965 ! HXD11_HUMAN-Phosphoserine203 [Term] id: CCO:B0055243 name: TLX1_HUMAN def: "T-cell leukemia homeobox protein 1" [UniProtKB:P31314] synonym: "Homeobox protein Hox-11" EXACT [UniProtKB:P31314] synonym: "Proto-oncogene TCL-3" EXACT [UniProtKB:P31314] synonym: "T-cell leukemia/lymphoma protein 3" EXACT [UniProtKB:P31314] xref: EMBL:AAA36719.1 xref: EMBL:AAA58662.1 xref: EMBL:AAB19293.1 xref: EMBL:AAG10096.1 xref: EMBL:CAA08834.1 xref: EMBL:CAH72448.1 xref: EMBL:EAW49778.1 xref: UniProtKB:O75699 xref: UniProtKB:P31314 xref: UniProtKB:Q5VXP2 xref: UniProtKB:Q9HCA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020285 ! TLX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055244 name: TIA1_HUMAN def: "Nucleolysin TIA-1 isoform p40" [UniProtKB:P31483] synonym: "p40-TIA-1" EXACT [UniProtKB:P31483] synonym: "RNA-binding protein TIA-1" EXACT [UniProtKB:P31483] xref: EMBL:AAD14053.1 xref: EMBL:AAX93193.1 xref: EMBL:EAW99824.1 xref: UniProtKB:P31483 xref: UniProtKB:Q53SS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020258 ! TIA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001745 ! poly(A) binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0071394 ! TIA1_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0071395 ! TIA1_HUMAN-Phosphoserine210 [Term] id: CCO:B0055245 name: ZEP2_HUMAN def: "Transcription factor HIVEP2" [UniProtKB:P31629] synonym: "HIV-EP2" EXACT [UniProtKB:P31629] synonym: "Human immunodeficiency virus type I enhancer-binding protein 2" EXACT [UniProtKB:P31629] synonym: "MBP-2" EXACT [UniProtKB:P31629] synonym: "MHC-binding protein 2" EXACT [UniProtKB:P31629] xref: EMBL:AAA36202.1 xref: EMBL:AAB88218.1 xref: EMBL:AAF81365.1 xref: EMBL:CAA19042.1 xref: EMBL:CAA46596.1 xref: UniProtKB:P31629 xref: UniProtKB:Q02646 xref: UniProtKB:Q5THT5 xref: UniProtKB:Q9NS05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020578 ! HIVEP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071995 ! ZEP2_HUMAN-Phosphoserine2071 relationship: transforms_into CCO:B0071996 ! ZEP2_HUMAN-Phosphoserine2077 [Term] id: CCO:B0055246 name: IL2RG_HUMAN def: "Cytokine receptor common gamma chain precursor" [UniProtKB:P31785] synonym: "CD132 antigen" EXACT [UniProtKB:P31785] synonym: "Gamma-C" EXACT [UniProtKB:P31785] synonym: "IL-2R gamma chain" EXACT [UniProtKB:P31785] synonym: "Interleukin-2 receptor gamma chain" EXACT [UniProtKB:P31785] synonym: "p64" EXACT [UniProtKB:P31785] xref: EMBL:AAA59145.1 xref: EMBL:AAC37524.1 xref: EMBL:AAH14972.1 xref: EMBL:AAT85803.1 xref: EMBL:BAA01857.1 xref: UniProtKB:P31785 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018262 ! IL2RG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017309 ! il7-il2rg-1 physical interaction relationship: participates_in CCO:I0017519 ! il7-il2rg-2 physical interaction relationship: participates_in CCO:I0017844 ! il2rg-il4r-1 physical interaction relationship: participates_in CCO:I0017846 ! il4r-il4-2 physical interaction relationship: participates_in CCO:I0017980 ! il4r-il4-3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067074 ! IL2RG_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0067075 ! IL2RG_HUMAN-Phosphotyrosine325 [Term] id: CCO:B0055247 name: FCG2B_HUMAN def: "Low affinity immunoglobulin gamma Fc region receptor II-b precursor" [UniProtKB:P31994] synonym: "CD32 antigen" EXACT [UniProtKB:P31994] synonym: "CDw32" EXACT [UniProtKB:P31994] synonym: "Fc-gamma RII-b" EXACT [UniProtKB:P31994] synonym: "Fc-gamma-RIIb" EXACT [UniProtKB:P31994] synonym: "FcRII-b" EXACT [UniProtKB:P31994] synonym: "IgG Fc receptor II-b" EXACT [UniProtKB:P31994] xref: EMBL:AAA35841.1 xref: EMBL:AAA35842.1 xref: EMBL:AAA35843.1 xref: EMBL:AAD00627.1 xref: EMBL:AAD00628.1 xref: EMBL:AAD00629.1 xref: EMBL:AAD00630.1 xref: EMBL:AAD00631.1 xref: EMBL:AAD00632.1 xref: EMBL:AAD00633.1 xref: EMBL:AAD00634.1 xref: EMBL:AAD00635.1 xref: EMBL:AAD00636.1 xref: EMBL:AAD00637.1 xref: EMBL:AAD00638.1 xref: EMBL:AAD00639.1 xref: EMBL:AAD00640.1 xref: EMBL:AAD00641.1 xref: EMBL:AAD00642.1 xref: EMBL:AAD00643.1 xref: EMBL:AAD00644.1 xref: EMBL:AAH31992.1 xref: EMBL:BAB92093.1 xref: EMBL:CAA35644.1 xref: EMBL:CAA35645.1 xref: EMBL:CAA36713.1 xref: EMBL:CAG28563.1 xref: UniProtKB:O95649 xref: UniProtKB:P31994 xref: UniProtKB:Q53X85 xref: UniProtKB:Q5VXA9 xref: UniProtKB:Q8NIA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017769 ! FCGR2B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004197 ! IgG binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017709 ! ighg1-fcg2b-9 direct interaction relationship: participates_in CCO:I0017710 ! ighg1-fcg2b-10 direct interaction relationship: participates_in CCO:I0017711 ! ighg1-fcg2b-11 direct interaction relationship: participates_in CCO:I0017712 ! ighg1-fcg2b-12 direct interaction relationship: participates_in CCO:I0017713 ! ighg1-fcg2b-13 direct interaction relationship: participates_in CCO:I0017714 ! ighg1-fcg2b-14 direct interaction relationship: participates_in CCO:I0017715 ! ighg1-fcg2b-15 direct interaction relationship: participates_in CCO:I0017716 ! ighg1-fcg2b-16 direct interaction relationship: participates_in CCO:I0017717 ! ighg1-fcg2b-17 direct interaction relationship: participates_in CCO:I0017718 ! ighg1-fcg2b-18 direct interaction relationship: participates_in CCO:I0017720 ! ighg1-fcg2b-20 direct interaction relationship: participates_in CCO:I0017721 ! ighg1-fcg2b-21 direct interaction relationship: participates_in CCO:I0017722 ! ighg1-fcg2b-22 direct interaction relationship: participates_in CCO:I0017723 ! ighg1-fcg2b-23 direct interaction relationship: participates_in CCO:I0017724 ! ighg1-fcg2b-24 direct interaction relationship: participates_in CCO:I0017725 ! ighg1-fcg2b-25 direct interaction relationship: participates_in CCO:I0017726 ! ighg1-fcg2b-26 direct interaction relationship: participates_in CCO:I0017727 ! ighg1-fcg2b-27 direct interaction relationship: participates_in CCO:I0017728 ! ighg1-fcg2b-28 direct interaction relationship: participates_in CCO:I0017729 ! ighg1-fcg2b-29 direct interaction relationship: participates_in CCO:I0017730 ! ighg1-fcg2b-30 direct interaction relationship: participates_in CCO:I0017731 ! ighg1-fcg2b-31 direct interaction relationship: participates_in CCO:I0017736 ! ighg1-fcg2b-19 direct interaction relationship: participates_in CCO:I0017737 ! ighg1-fcg2b-8 direct interaction relationship: participates_in CCO:I0018219 ! ighg1-fcg2b-1 direct interaction relationship: participates_in CCO:I0018220 ! ighg1-fcg2b-2 direct interaction relationship: participates_in CCO:I0018221 ! ighg1-fcg2b-3 direct interaction relationship: participates_in CCO:I0018222 ! ighg1-fcg2b-4 direct interaction relationship: participates_in CCO:I0018223 ! ighg1-fcg2b-5 direct interaction relationship: participates_in CCO:I0018224 ! ighg1-fcg2b-6 direct interaction relationship: participates_in CCO:I0018225 ! ighg1-fcg2b-7 direct interaction relationship: participates_in CCO:I0020552 ! fcgr2b-c14orf1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055248 name: I5P2_HUMAN def: "Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor" [UniProtKB:P32019] synonym: "5PTase" EXACT [UniProtKB:P32019] synonym: "75 kDa inositol polyphosphate-5-phosphatase" EXACT [UniProtKB:P32019] synonym: "EC 3.1.3.36" EXACT [UniProtKB:P32019] synonym: "Phosphoinositide 5-phosphatase" EXACT [UniProtKB:P32019] xref: EMBL:AAA79207.1 xref: EMBL:AAH42529.2 xref: EMBL:AAH58932.1 xref: EMBL:CAH56301.1 xref: EMBL:CAH69926.1 xref: EMBL:CAH69928.1 xref: EMBL:CAH69929.1 xref: EMBL:CAH70076.1 xref: EMBL:CAH70079.1 xref: EMBL:CAH70080.1 xref: UniProtKB:P32019 xref: UniProtKB:Q5VSG9 xref: UniProtKB:Q5VSH0 xref: UniProtKB:Q5VSH1 xref: UniProtKB:Q658Q5 xref: UniProtKB:Q6P6D4 xref: UniProtKB:Q6PD53 xref: UniProtKB:Q86YE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018205 ! INPP5B_human relationship: has_function CCO:F0000198 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0000845 ! inositol-polyphosphate 5-phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055249 name: PRDX2_HUMAN def: "Peroxiredoxin-2" [UniProtKB:P32119] synonym: "EC 1.11.1.15" EXACT [UniProtKB:P32119] synonym: "Natural killer cell-enhancing factor B" EXACT [UniProtKB:P32119] synonym: "NKEF-B" EXACT [UniProtKB:P32119] synonym: "PRP" EXACT [UniProtKB:P32119] synonym: "Thiol-specific antioxidant protein" EXACT [UniProtKB:P32119] synonym: "Thioredoxin peroxidase 1" EXACT [UniProtKB:P32119] synonym: "Thioredoxin-dependent peroxide reductase 1" EXACT [UniProtKB:P32119] synonym: "TSA" EXACT [UniProtKB:P32119] xref: EMBL:AAA50465.1 xref: EMBL:AAH00452.1 xref: EMBL:AAH03022.1 xref: EMBL:AAH39428.1 xref: EMBL:ABB02182.1 xref: EMBL:CAA57764.1 xref: EMBL:CAA80269.1 xref: EMBL:CAG29352.1 xref: EMBL:CAG46588.1 xref: UniProtKB:P31945 xref: UniProtKB:P32118 xref: UniProtKB:P32119 xref: UniProtKB:P35701 xref: UniProtKB:Q6FHG4 xref: UniProtKB:Q92763 xref: UniProtKB:Q9UC23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019502 ! PRDX2_human relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001854 ! thioredoxin peroxidase activity relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0008212 ! peroxiredoxin activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0069497 ! PRDX2_HUMAN-N-acetylalanine2 [Term] id: CCO:B0055250 name: ARRB2_HUMAN def: "Beta-arrestin-2" [UniProtKB:P32121] synonym: "Arrestin beta-2" EXACT [UniProtKB:P32121] xref: EMBL:AAC99468.1 xref: EMBL:AAH07427.1 xref: EMBL:AAH67368.1 xref: EMBL:ABC40725.1 xref: EMBL:ABG47460.1 xref: EMBL:BAC05094.1 xref: EMBL:CAA77577.1 xref: EMBL:CAG29306.1 xref: UniProtKB:P32121 xref: UniProtKB:Q0Z8D3 xref: UniProtKB:Q2PP19 xref: UniProtKB:Q6ICT3 xref: UniProtKB:Q8N7Y2 xref: UniProtKB:Q9UEQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017050 ! ARRB2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0019899 ! arrb2-med8 physical interaction relationship: participates_in CCO:I0019900 ! arrb2-stc2 physical interaction relationship: participates_in CCO:I0020240 ! arrb2-smarcc2 physical interaction relationship: participates_in CCO:I0020514 ! arrb2-ndufs7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0063617 ! ARRB2_HUMAN-Phosphotyrosine48 [Term] id: CCO:B0055251 name: CCKAR_HUMAN def: "Cholecystokinin receptor type A" [UniProtKB:P32238] synonym: "CCK-A receptor" EXACT [UniProtKB:P32238] synonym: "CCK-AR" EXACT [UniProtKB:P32238] synonym: "CCK1-R" EXACT [UniProtKB:P32238] synonym: "Cholecystokinin-1 receptor" EXACT [UniProtKB:P32238] xref: EMBL:AAA02819.1 xref: EMBL:AAA35659.1 xref: EMBL:AAA91123.1 xref: EMBL:AAH74987.1 xref: EMBL:AAP84362.1 xref: EMBL:BAA90879.1 xref: UniProtKB:P32238 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017258 ! CCKAR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001293 ! cholecystokinin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0055252 name: GASR_HUMAN def: "Gastrin/cholecystokinin type B receptor" [UniProtKB:P32239] synonym: "CCK-B receptor" EXACT [UniProtKB:P32239] synonym: "CCK-BR" EXACT [UniProtKB:P32239] synonym: "CCK2-R" EXACT [UniProtKB:P32239] synonym: "Cholecystokinin-2 receptor" EXACT [UniProtKB:P32239] xref: EMBL:AAA35657.1 xref: EMBL:AAA35660.1 xref: EMBL:AAA91831.1 xref: EMBL:AAB30766.2 xref: EMBL:AAC27510.1 xref: EMBL:AAC37528.1 xref: EMBL:AAF67174.1 xref: EMBL:AAH00740.1 xref: EMBL:AAK38351.1 xref: EMBL:AAN32829.1 xref: EMBL:AAP35435.1 xref: EMBL:AAP84364.1 xref: EMBL:BAA02564.1 xref: EMBL:BAA04759.2 xref: EMBL:BAF84753.1 xref: UniProtKB:A8K7P9 xref: UniProtKB:O75824 xref: UniProtKB:P32239 xref: UniProtKB:Q16144 xref: UniProtKB:Q92492 xref: UniProtKB:Q96LC6 xref: UniProtKB:Q9NYK7 xref: UniProtKB:Q9UBV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017867 ! CCKBR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001293 ! cholecystokinin receptor activity relationship: has_function CCO:F0002547 ! gastrin receptor activity relationship: has_function CCO:F0006279 ! 1-phosphatidylinositol-3-kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055253 name: VIPR1_HUMAN def: "Vasoactive intestinal polypeptide receptor 1 precursor" [UniProtKB:P32241] synonym: "PACAP type II receptor" EXACT [UniProtKB:P32241] synonym: "PACAP-R-2" EXACT [UniProtKB:P32241] synonym: "Pituitary adenylate cyclase-activating polypeptide type II receptor" EXACT [UniProtKB:P32241] synonym: "VIP-R-1" EXACT [UniProtKB:P32241] xref: EMBL:AAA36802.1 xref: EMBL:AAA36805.1 xref: EMBL:AAB60362.1 xref: EMBL:BAC05895.1 xref: EMBL:CAA53046.1 xref: EMBL:CAA54814.1 xref: UniProtKB:P32241 xref: UniProtKB:Q15871 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020450 ! VIPR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0071808 ! VIPR1_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0071809 ! VIPR1_HUMAN-Phosphoserine455 [Term] id: CCO:B0055254 name: OTX1_HUMAN def: "Homeobox protein OTX1" [UniProtKB:P32242] synonym: "Orthodenticle homolog 1" EXACT [UniProtKB:P32242] xref: EMBL:AAH07621.1 xref: EMBL:AAY24357.1 xref: UniProtKB:P32242 xref: UniProtKB:Q53TG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019248 ! OTX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014971 ! krtap4_12-otx1 physical interaction relationship: participates_in CCO:I0015321 ! mdfi-otx1 physical interaction relationship: participates_in CCO:I0015751 ! chic2-otx1 physical interaction relationship: participates_in CCO:I0015772 ! otx1-rbpms physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055255 name: OTX2_HUMAN def: "Homeobox protein OTX2" [UniProtKB:P32243] synonym: "Orthodenticle homolog 2" EXACT [UniProtKB:P32243] xref: EMBL:AAD31385.1 xref: EMBL:AAG16243.1 xref: EMBL:AAH32579.1 xref: EMBL:BAA90425.1 xref: UniProtKB:P32243 xref: UniProtKB:Q6GTV3 xref: UniProtKB:Q9HAW3 xref: UniProtKB:Q9P2R1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019249 ! OTX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001770 ! eukaryotic initiation factor 4E binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001006 ! growth cone relationship: participates_in CCO:I0017604 ! atxn1-otx2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000826 ! regulation of smoothened signaling pathway relationship: participates_in CCO:P0002026 ! regulation of fibroblast growth factor receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055256 name: CCR1_HUMAN def: "C-C chemokine receptor type 1" [UniProtKB:P32246] synonym: "C-C CKR-1" EXACT [UniProtKB:P32246] synonym: "CC-CKR-1" EXACT [UniProtKB:P32246] synonym: "CCR-1" EXACT [UniProtKB:P32246] synonym: "CCR1" EXACT [UniProtKB:P32246] synonym: "CD191 antigen" EXACT [UniProtKB:P32246] synonym: "HM145" EXACT [UniProtKB:P32246] synonym: "LD78 receptor" EXACT [UniProtKB:P32246] synonym: "Macrophage inflammatory protein 1-alpha receptor" EXACT [UniProtKB:P32246] synonym: "MIP-1alpha-R" EXACT [UniProtKB:P32246] synonym: "RANTES-R" EXACT [UniProtKB:P32246] xref: EMBL:AAA36543.1 xref: EMBL:AAA58408.1 xref: EMBL:AAH51306.2 xref: EMBL:AAH64991.1 xref: EMBL:BAA01723.1 xref: UniProtKB:P32246 xref: UniProtKB:Q86VA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017276 ! CCR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017879 ! ccr1-plp2-2 physical interaction relationship: participates_in CCO:I0018193 ! ccr1-plp2-3 colocalization relationship: participates_in CCO:I0018648 ! ccr1-plp2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0055257 name: BRS3_HUMAN def: "Bombesin receptor subtype-3" [UniProtKB:P32247] synonym: "BRS-3" EXACT [UniProtKB:P32247] xref: EMBL:AAA35604.1 xref: EMBL:AAT79496.1 xref: EMBL:CAA54031.1 xref: EMBL:CAB10731.1 xref: UniProtKB:P32247 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017181 ! BRS3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001288 ! bombesin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055258 name: CCR7_HUMAN def: "C-C chemokine receptor type 7 precursor" [UniProtKB:P32248] synonym: "BLR2" EXACT [UniProtKB:P32248] synonym: "C-C CKR-7" EXACT [UniProtKB:P32248] synonym: "CC-CKR-7" EXACT [UniProtKB:P32248] synonym: "CCR-7" EXACT [UniProtKB:P32248] synonym: "CD197 antigen" EXACT [UniProtKB:P32248] synonym: "CDw197" EXACT [UniProtKB:P32248] synonym: "EBI1" EXACT [UniProtKB:P32248] synonym: "EBV-induced G-protein coupled receptor 1" EXACT [UniProtKB:P32248] synonym: "MIP-3 beta receptor" EXACT [UniProtKB:P32248] xref: EMBL:AAA58615.1 xref: EMBL:AAA74230.1 xref: EMBL:AAA74231.1 xref: EMBL:AAH35343.1 xref: EMBL:AAT52232.1 xref: UniProtKB:P32248 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017282 ! CCR7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0064132 ! CCR7_HUMAN-Phosphoserine151 [Term] id: CCO:B0055259 name: GRK4_HUMAN def: "G protein-coupled receptor kinase 4" [UniProtKB:P32298] synonym: "EC 2.7.11.16" EXACT [UniProtKB:P32298] synonym: "G protein-coupled receptor kinase GRK4" EXACT [UniProtKB:P32298] synonym: "ITI1" EXACT [UniProtKB:P32298] xref: EMBL:AAB04045.1 xref: EMBL:AAC50406.1 xref: EMBL:AAC50407.1 xref: EMBL:AAC50408.1 xref: EMBL:AAC50409.1 xref: EMBL:AAC50410.1 xref: EMBL:AAC50411.1 xref: EMBL:AAC50412.1 xref: EMBL:AAI17321.1 xref: EMBL:CAA53506.1 xref: EMBL:CAA66468.1 xref: EMBL:CAA66469.1 xref: EMBL:CAA66470.1 xref: EMBL:CAA66802.1 xref: EMBL:CAA92341.1 xref: UniProtKB:O00641 xref: UniProtKB:O00642 xref: UniProtKB:P32298 xref: UniProtKB:Q13293 xref: UniProtKB:Q13294 xref: UniProtKB:Q13295 xref: UniProtKB:Q14453 xref: UniProtKB:Q14725 xref: UniProtKB:Q15313 xref: UniProtKB:Q15314 xref: UniProtKB:Q15315 xref: UniProtKB:Q15316 xref: UniProtKB:Q17RH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018071 ! GRK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055260 name: CXCR5_HUMAN def: "C-X-C chemokine receptor type 5" [UniProtKB:P32302] synonym: "Burkitt lymphoma receptor 1" EXACT [UniProtKB:P32302] synonym: "CD185 antigen" EXACT [UniProtKB:P32302] synonym: "CXC-R5" EXACT [UniProtKB:P32302] synonym: "CXCR-5" EXACT [UniProtKB:P32302] synonym: "MDR-15" EXACT [UniProtKB:P32302] synonym: "Monocyte-derived receptor 15" EXACT [UniProtKB:P32302] xref: EMBL:CAA48252.1 xref: EMBL:CAA48723.1 xref: UniProtKB:P32302 xref: UniProtKB:Q14811 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017501 ! CXCR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055261 name: STX2_HUMAN def: "Syntaxin-2" [UniProtKB:P32856] synonym: "Epimorphin" EXACT [UniProtKB:P32856] xref: EMBL:AAH47496.1 xref: EMBL:BAA03436.1 xref: UniProtKB:P32856 xref: UniProtKB:Q86VW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020079 ! STX2_human relationship: has_function CCO:F0000027 ! SNARE binding relationship: has_function CCO:F0001631 ! SNAP receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001017 ! midbody relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000456 ! cell separation during cytokinesis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055262 name: CD70_HUMAN def: "CD70 antigen" [UniProtKB:P32970] synonym: "CD27 ligand" EXACT [UniProtKB:P32970] synonym: "CD27-L" EXACT [UniProtKB:P32970] synonym: "CD70 antigen" EXACT [UniProtKB:P32970] synonym: "Tumor necrosis factor ligand superfamily member 7" EXACT [UniProtKB:P32970] xref: EMBL:AAA36175.1 xref: EMBL:AAB30121.1 xref: EMBL:AAH00725.1 xref: UniProtKB:P32970 xref: UniProtKB:Q96J57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017307 ! CD70_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000050 ! integral to membrane of membrane fraction relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055263 name: TNFL8_HUMAN def: "Tumor necrosis factor ligand superfamily member 8" [UniProtKB:P32971] synonym: "CD153 antigen" EXACT [UniProtKB:P32971] synonym: "CD30 ligand" EXACT [UniProtKB:P32971] synonym: "CD30-L" EXACT [UniProtKB:P32971] xref: EMBL:AAA74594.1 xref: EMBL:AAB97877.1 xref: UniProtKB:O43404 xref: UniProtKB:P32971 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020305 ! TNFSF8_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055264 name: ACSL1_HUMAN def: "Long-chain-fatty-acid--CoA ligase 1" [UniProtKB:P33121] synonym: "ACS1" EXACT [UniProtKB:P33121] synonym: "Acyl-CoA synthetase 1" EXACT [UniProtKB:P33121] synonym: "EC 6.2.1.3" EXACT [UniProtKB:P33121] synonym: "LACS 1" EXACT [UniProtKB:P33121] synonym: "LACS 2" EXACT [UniProtKB:P33121] synonym: "Long-chain acyl-CoA synthetase 1" EXACT [UniProtKB:P33121] synonym: "Long-chain acyl-CoA synthetase 2" EXACT [UniProtKB:P33121] synonym: "Long-chain fatty acid-CoA ligase 2" EXACT [UniProtKB:P33121] synonym: "Palmitoyl-CoA ligase 1" EXACT [UniProtKB:P33121] synonym: "Palmitoyl-CoA ligase 2" EXACT [UniProtKB:P33121] xref: EMBL:AAB00959.1 xref: EMBL:AAH26290.1 xref: EMBL:AAH50073.1 xref: EMBL:BAA00931.1 xref: EMBL:BAC04704.1 xref: UniProtKB:P33121 xref: UniProtKB:P41215 xref: UniProtKB:Q8N8V7 xref: UniProtKB:Q8TA99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016904 ! ACSL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation relationship: transforms_into CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0065390 ! ACSL1_HUMAN-Phosphotyrosine84 relationship: transforms_into CCO:B0065391 ! ACSL1_HUMAN-N6-acetyllysine543 relationship: transforms_into CCO:B0065392 ! ACSL1_HUMAN-N6-acetyllysine632 [Term] id: CCO:B0055265 name: LSP1_HUMAN def: "Lymphocyte-specific protein 1" [UniProtKB:P33241] synonym: "47 kDa actin-binding protein" EXACT [UniProtKB:P33241] synonym: "52 kDa phosphoprotein" EXACT [UniProtKB:P33241] synonym: "Lymphocyte-specific antigen WP34" EXACT [UniProtKB:P33241] synonym: "Protein pp52" EXACT [UniProtKB:P33241] xref: EMBL:AAA59534.1 xref: EMBL:AAB29545.1 xref: EMBL:AAH01785.1 xref: EMBL:CAA38971.1 xref: UniProtKB:P33241 xref: UniProtKB:Q16096 xref: UniProtKB:Q9BUY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018526 ! LSP1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067789 ! LSP1_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0067790 ! LSP1_HUMAN-Phosphothreonine175 relationship: transforms_into CCO:B0067791 ! LSP1_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0067792 ! LSP1_HUMAN-Phosphoserine252 [Term] id: CCO:B0055266 name: DUT_HUMAN def: "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor" [UniProtKB:P33316] synonym: "dUTP pyrophosphatase" EXACT [UniProtKB:P33316] synonym: "dUTPase" EXACT [UniProtKB:P33316] synonym: "EC 3.6.1.23" EXACT [UniProtKB:P33316] xref: EMBL:AAA36801.1 xref: EMBL:AAA58444.1 xref: EMBL:AAB71393.1 xref: EMBL:AAB71394.1 xref: EMBL:AAB93866.1 xref: EMBL:AAB93867.1 xref: EMBL:AAB94642.1 xref: EMBL:AAC50418.1 xref: EMBL:AAC51123.1 xref: EMBL:AAH33645.1 xref: EMBL:AAH70339.1 xref: EMBL:AAI10378.1 xref: EMBL:AAX14045.1 xref: EMBL:BAB13724.1 xref: EMBL:EAW77350.1 xref: UniProtKB:O14785 xref: UniProtKB:P33316 xref: UniProtKB:Q16708 xref: UniProtKB:Q16860 xref: UniProtKB:Q6NSA3 xref: UniProtKB:Q96Q81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017637 ! DUT_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000641 ! dUTP diphosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015127 ! dut-spata2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0064907 ! DUT_HUMAN-Phosphoserine99 [Term] id: CCO:B0055267 name: GCYA2_HUMAN def: "Guanylate cyclase soluble subunit alpha-2" [UniProtKB:P33402] synonym: "EC 4.6.1.2" EXACT [UniProtKB:P33402] synonym: "GCS-alpha-2" EXACT [UniProtKB:P33402] xref: EMBL:CAA44921.1 xref: EMBL:CAA90393.1 xref: UniProtKB:P33402 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017898 ! GUCY1A2_human relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055268 name: CD80_HUMAN def: "T-lymphocyte activation antigen CD80 precursor" [UniProtKB:P33681] synonym: "Activation B7-1 antigen" EXACT [UniProtKB:P33681] synonym: "B7" EXACT [UniProtKB:P33681] synonym: "BB1" EXACT [UniProtKB:P33681] synonym: "CD80 antigen" EXACT [UniProtKB:P33681] synonym: "CTLA-4 counter-receptor B7.1" EXACT [UniProtKB:P33681] xref: EMBL:AAA36045.1 xref: EMBL:AAA58390.1 xref: EMBL:AAH42665.1 xref: UniProtKB:P33681 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017311 ! CD80_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017265 ! cd80-ctla4-1 direct interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000885 ! positive regulation of signal transduction relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002366 ! positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process relationship: participates_in CCO:P0002441 ! positive regulation of T-helper 1 cell differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:B0055269 name: AA3R_HUMAN def: "Adenosine A3 receptor" [UniProtKB:P33765] xref: EMBL:AAA16365.1 xref: EMBL:AAA35949.1 xref: EMBL:AAB02790.1 xref: EMBL:AAG35155.1 xref: EMBL:AAH29831.1 xref: EMBL:AAN01275.1 xref: EMBL:AAQ89007.1 xref: EMBL:CAA54288.1 xref: EMBL:CAC36045.1 xref: UniProtKB:P33765 xref: UniProtKB:Q6UWU0 xref: UniProtKB:Q9BYZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016864 ! ADORA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0065229 ! AA3R_HUMAN-Phosphoserine317 [Term] id: CCO:B0055270 name: NTF4_HUMAN def: "Neurotrophin-4 precursor" [UniProtKB:P34130] synonym: "Neurotrophin-5" EXACT [UniProtKB:P34130] synonym: "Neutrophic factor 4" EXACT [UniProtKB:P34130] synonym: "NT-4" EXACT [UniProtKB:P34130] synonym: "NT-5" EXACT [UniProtKB:P34130] xref: EMBL:AAA60154.1 xref: EMBL:AAH12421.1 xref: EMBL:AAV38175.1 xref: EMBL:AAV38176.1 xref: EMBL:CAG46698.1 xref: UniProtKB:P34130 xref: UniProtKB:Q6FH56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018882 ! NTF4_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0002784 ! regulation of synaptic plasticity [Term] id: CCO:B0055271 name: GRK5_HUMAN def: "G protein-coupled receptor kinase 5" [UniProtKB:P34947] synonym: "EC 2.7.11.16" EXACT [UniProtKB:P34947] synonym: "G protein-coupled receptor kinase GRK5" EXACT [UniProtKB:P34947] xref: EMBL:AAA58620.1 xref: EMBL:AAH64506.1 xref: EMBL:CAI15804.1 xref: EMBL:CAI16487.1 xref: EMBL:CAI16759.1 xref: EMBL:EAW49394.1 xref: UniProtKB:P34947 xref: UniProtKB:Q5T059 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018072 ! GRK5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066619 ! GRK5_HUMAN-Phosphoserine484 relationship: transforms_into CCO:B0066620 ! GRK5_HUMAN-Phosphothreonine485 [Term] id: CCO:B0055272 name: 5HT7R_HUMAN def: "5-hydroxytryptamine receptor 7" [UniProtKB:P34969] synonym: "5-HT-7" EXACT [UniProtKB:P34969] synonym: "5-HT-X" EXACT [UniProtKB:P34969] synonym: "5HT7" EXACT [UniProtKB:P34969] synonym: "Serotonin receptor 7" EXACT [UniProtKB:P34969] xref: EMBL:AAB48393.1 xref: EMBL:AAB48394.1 xref: EMBL:AAB48397.2 xref: EMBL:AAC37538.1 xref: EMBL:AAF07217.1 xref: EMBL:AAF07218.1 xref: EMBL:AAH47526.1 xref: EMBL:AAR87480.1 xref: EMBL:CAH69968.1 xref: EMBL:EAW50118.1 xref: UniProtKB:P34969 xref: UniProtKB:P78336 xref: UniProtKB:P78372 xref: UniProtKB:P78516 xref: UniProtKB:Q5VX01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016859 ! HTR7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055273 name: CNR2_HUMAN def: "Cannabinoid receptor 2" [UniProtKB:P34972] synonym: "CB-2" EXACT [UniProtKB:P34972] synonym: "CB2" EXACT [UniProtKB:P34972] synonym: "CX5" EXACT [UniProtKB:P34972] xref: EMBL:AAO92299.1 xref: EMBL:CAA52376.1 xref: EMBL:CAD22548.1 xref: EMBL:CAD22549.1 xref: UniProtKB:P34972 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017411 ! CNR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001291 ! cannabinoid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055274 name: TRFR_HUMAN def: "Thyrotropin-releasing hormone receptor" [UniProtKB:P34981] synonym: "Thyroliberin receptor" EXACT [UniProtKB:P34981] synonym: "TRH-R" EXACT [UniProtKB:P34981] xref: EMBL:AAB32222.1 xref: EMBL:AAI05046.1 xref: EMBL:AAI13361.1 xref: EMBL:AAR84356.1 xref: EMBL:BAA04120.1 xref: EMBL:BAA12796.1 xref: EMBL:CAA09746.1 xref: EMBL:CAA50979.1 xref: EMBL:CAA52965.1 xref: UniProtKB:P34981 xref: UniProtKB:Q2M339 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020351 ! TRHR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001335 ! thyrotropin-releasing hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055275 name: PE2R1_HUMAN def: "Prostaglandin E2 receptor EP1 subtype" [UniProtKB:P34995] synonym: "PGE receptor, EP1 subtype" EXACT [UniProtKB:P34995] synonym: "Prostanoid EP1 receptor" EXACT [UniProtKB:P34995] xref: EMBL:AAC37539.1 xref: EMBL:AAH39034.1 xref: EMBL:AAH51286.1 xref: EMBL:AAP32302.1 xref: EMBL:BAC05723.1 xref: UniProtKB:P34995 xref: UniProtKB:Q5U5U4 xref: UniProtKB:Q86UH3 xref: UniProtKB:Q86VB5 xref: UniProtKB:Q8NHB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019355 ! PTGER1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055276 name: CRFR1_HUMAN def: "Corticotropin-releasing factor receptor 1 precursor" [UniProtKB:P34998] synonym: "Corticotropin-releasing hormone receptor 1" EXACT [UniProtKB:P34998] synonym: "CRF-R" EXACT [UniProtKB:P34998] synonym: "CRF1" EXACT [UniProtKB:P34998] synonym: "CRH-R 1" EXACT [UniProtKB:P34998] xref: EMBL:AAA35718.1 xref: EMBL:AAA35719.1 xref: EMBL:AAC50073.1 xref: EMBL:AAC69993.1 xref: EMBL:AAD52688.1 xref: EMBL:AAR19768.1 xref: EMBL:CAA51052.1 xref: UniProtKB:P34998 xref: UniProtKB:Q13008 xref: UniProtKB:Q9UK64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017454 ! CRHR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002549 ! corticotrophin-releasing factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:B0055277 name: UBP6_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 6" [UniProtKB:P35125] synonym: "Deubiquitinating enzyme 6" EXACT [UniProtKB:P35125] synonym: "EC 3.1.2.15" EXACT [UniProtKB:P35125] synonym: "Proto-oncogene TRE-2" EXACT [UniProtKB:P35125] synonym: "Ubiquitin thioesterase 6" EXACT [UniProtKB:P35125] synonym: "Ubiquitin-specific-processing protease 6" EXACT [UniProtKB:P35125] xref: EMBL:AAN38838.1 xref: EMBL:AAO21348.1 xref: EMBL:CAA45108.1 xref: EMBL:CAA45111.1 xref: UniProtKB:P35125 xref: UniProtKB:Q15634 xref: UniProtKB:Q86WP6 xref: UniProtKB:Q8IWT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020401 ! USP6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:I0017617 ! atxn7l3-usp6 physical interaction relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0055278 name: CAH8_HUMAN def: "Carbonic anhydrase-related protein" [UniProtKB:P35219] synonym: "CA-VIII" EXACT [UniProtKB:P35219] synonym: "Carbonic anhydrase VIII" EXACT [UniProtKB:P35219] synonym: "CARP" EXACT [UniProtKB:P35219] xref: EMBL:AAA35653.2 xref: EMBL:AAH69744.1 xref: EMBL:AAH69794.1 xref: EMBL:AAI08930.1 xref: EMBL:AAL78170.1 xref: UniProtKB:P35219 xref: UniProtKB:Q32MY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017214 ! CA8_human relationship: has_function CCO:F0000564 ! carbonate dehydratase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020264 ! ca8-lrch4 physical interaction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0055279 name: BMI1_HUMAN def: "Polycomb complex protein BMI-1" [UniProtKB:P35226] synonym: "Polycomb group RING finger protein 4" EXACT [UniProtKB:P35226] synonym: "RING finger protein 51" EXACT [UniProtKB:P35226] xref: EMBL:AAA19873.1 xref: EMBL:AAB27059.1 xref: EMBL:AAH11652.1 xref: UniProtKB:P35226 xref: UniProtKB:Q16030 xref: UniProtKB:Q96F37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005999 ! BMI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000947 ! regulation of gene expression relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: transforms_into CCO:B0063942 ! BMI1_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0063943 ! BMI1_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0063944 ! BMI1_HUMAN-Phosphoserine255 [Term] id: CCO:B0055280 name: PCGF2_HUMAN def: "Polycomb group RING finger protein 2" [UniProtKB:P35227] synonym: "DNA-binding protein Mel-18" EXACT [UniProtKB:P35227] synonym: "RING finger protein 110" EXACT [UniProtKB:P35227] synonym: "Zinc finger protein 144" EXACT [UniProtKB:P35227] xref: EMBL:AAH04858.1 xref: EMBL:AAH24255.1 xref: EMBL:BAA03074.1 xref: EMBL:EAW60528.1 xref: UniProtKB:A6NGD8 xref: UniProtKB:P35227 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019319 ! PCGF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069152 ! PCGF2_HUMAN-Phosphothreonine344 [Term] id: CCO:B0055281 name: RECO_HUMAN def: "Recoverin" [UniProtKB:P35243] synonym: "Cancer-associated retinopathy protein" EXACT [UniProtKB:P35243] synonym: "Protein CAR" EXACT [UniProtKB:P35243] xref: EMBL:AAB23163.1 xref: EMBL:AAB23392.1 xref: EMBL:AAB26894.1 xref: EMBL:AAH01720.1 xref: EMBL:BAA19460.1 xref: UniProtKB:P35243 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019662 ! RCVRN_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001692 ! calcium sensitive guanylate cyclase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017619 ! pqbp1-rcv1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055282 name: SFTPD_HUMAN def: "Pulmonary surfactant-associated protein D precursor" [UniProtKB:P35247] synonym: "Lung surfactant protein D" EXACT [UniProtKB:P35247] synonym: "PSP-D" EXACT [UniProtKB:P35247] synonym: "SP-D" EXACT [UniProtKB:P35247] xref: EMBL:AAB59450.1 xref: EMBL:AAH22318.1 xref: EMBL:AAO22991.1 xref: EMBL:CAA46152.1 xref: EMBL:CAG46746.1 xref: EMBL:CAI14436.1 xref: UniProtKB:P35247 xref: UniProtKB:Q5T0M3 xref: UniProtKB:Q6FH08 xref: UniProtKB:Q86YK9 xref: UniProtKB:Q8TCD8 xref: UniProtKB:Q9UCJ2 xref: UniProtKB:Q9UCJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019879 ! SFTPD_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001847 ! bacterial binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation relationship: participates_in CCO:P0002277 ! negative regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis relationship: transforms_into CCO:B0070443 ! SFTPD_HUMAN-4-hydroxyproline78 relationship: transforms_into CCO:B0070444 ! SFTPD_HUMAN-5-hydroxylysine87 relationship: transforms_into CCO:B0070445 ! SFTPD_HUMAN-4-hydroxyproline96 relationship: transforms_into CCO:B0070446 ! SFTPD_HUMAN-5-hydroxylysine99 relationship: transforms_into CCO:B0070447 ! SFTPD_HUMAN-4-hydroxyproline171 relationship: transforms_into CCO:B0070448 ! SFTPD_HUMAN-4-hydroxyproline177 [Term] id: CCO:B0055283 name: ZN123_HUMAN xref: UniProtKB:P35273 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055284 name: ZN125_HUMAN xref: UniProtKB:P35274 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055285 name: ZN126_HUMAN xref: UniProtKB:P35275 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055286 name: ADML_HUMAN def: "ADM precursor" [UniProtKB:P35318] xref: EMBL:AAC60642.1 xref: EMBL:AAH15961.1 xref: EMBL:AAP35548.1 xref: EMBL:AAZ38717.1 xref: EMBL:BAA03589.1 xref: EMBL:BAA07756.1 xref: EMBL:CAG46792.1 xref: UniProtKB:P35318 xref: UniProtKB:Q6FGW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016918 ! ADM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0065424 ! ADML_HUMAN-Arginine amide41 relationship: transforms_into CCO:B0065425 ! ADML_HUMAN-Tyrosine amide146 [Term] id: CCO:B0055287 name: HRH1_HUMAN def: "Histamine H1 receptor" [UniProtKB:P35367] xref: EMBL:AAB95156.1 xref: EMBL:AAN01269.1 xref: EMBL:BAA03319.1 xref: EMBL:BAA05840.1 xref: EMBL:BAA94465.1 xref: EMBL:CAA54182.1 xref: EMBL:CAA84380.1 xref: UniProtKB:P35367 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018159 ! HRH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: transforms_into CCO:B0066895 ! HRH1_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0066896 ! HRH1_HUMAN-Phosphothreonine279 [Term] id: CCO:B0055288 name: PE2R4_HUMAN def: "Prostaglandin E2 receptor EP4 subtype" [UniProtKB:P35408] synonym: "PGE receptor, EP4 subtype" EXACT [UniProtKB:P35408] synonym: "Prostanoid EP4 receptor" EXACT [UniProtKB:P35408] xref: EMBL:AAA36434.1 xref: EMBL:AAA36438.1 xref: EMBL:AAI01535.1 xref: EMBL:AAI13524.1 xref: EMBL:AAR07904.1 xref: EMBL:ABD48960.1 xref: EMBL:BAA05834.1 xref: EMBL:CAA66463.1 xref: UniProtKB:P35408 xref: UniProtKB:Q3MJ87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019357 ! PTGER4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001297 ! prostaglandin receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:B0055289 name: MAS1L_HUMAN def: "Mas-related G-protein coupled receptor MRG" [UniProtKB:P35410] synonym: "MAS-R" EXACT [UniProtKB:P35410] synonym: "MAS1-like" EXACT [UniProtKB:P35410] xref: EMBL:AAB21255.1 xref: EMBL:AAH69127.1 xref: EMBL:AAH69345.1 xref: EMBL:CAB44503.1 xref: UniProtKB:P35410 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018571 ! MAS1L_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055290 name: APJ_HUMAN def: "Apelin receptor" [UniProtKB:P35414] synonym: "Angiotensin receptor-like 1" EXACT [UniProtKB:P35414] synonym: "G-protein coupled receptor APJ" EXACT [UniProtKB:P35414] synonym: "HG11" EXACT [UniProtKB:P35414] xref: EMBL:AAA18954.1 xref: EMBL:AAH32688.1 xref: EMBL:CAA61546.1 xref: UniProtKB:P35414 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016990 ! APLNR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055291 name: HXD12_HUMAN def: "Homeobox protein Hox-D12" [UniProtKB:P35452] synonym: "Hox-4H" EXACT [UniProtKB:P35452] xref: EMBL:AAF79044.1 xref: UniProtKB:P35452 xref: UniProtKB:Q9NS03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018191 ! HOXD12_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055292 name: HXD13_HUMAN def: "Homeobox protein Hox-D13" [UniProtKB:P35453] synonym: "Hox-4I" EXACT [UniProtKB:P35453] xref: EMBL:AAC51635.1 xref: EMBL:BAA95352.1 xref: UniProtKB:P35453 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018192 ! HOXD13_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055293 name: DRD3_HUMAN def: "D(3) dopamine receptor" [UniProtKB:P35462] xref: EMBL:AAA03543.1 xref: EMBL:AAA64369.1 xref: EMBL:AAA73929.1 xref: EMBL:AAH95510.1 xref: UniProtKB:P35462 xref: UniProtKB:Q4VBM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017619 ! DRD3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway [Term] id: CCO:B0055294 name: MSX2_HUMAN def: "Homeobox protein MSX-2" [UniProtKB:P35548] synonym: "Hox-8" EXACT [UniProtKB:P35548] xref: EMBL:AAB33867.1 xref: EMBL:AAB42178.1 xref: EMBL:AAD14169.1 xref: EMBL:AAH15509.1 xref: EMBL:BAA03611.1 xref: EMBL:BAA06549.1 xref: EMBL:BAA13949.1 xref: EMBL:CAA49156.1 xref: UniProtKB:P35548 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018667 ! MSX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055295 name: TIE1_HUMAN def: "Tyrosine-protein kinase receptor Tie-1 precursor" [UniProtKB:P35590] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P35590] xref: EMBL:AAH38239.1 xref: EMBL:CAA43290.1 xref: UniProtKB:P35590 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020263 ! TIE1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071400 ! TIE1_HUMAN-Phosphotyrosine1007 [Term] id: CCO:B0055296 name: BASI_HUMAN def: "Basigin precursor" [UniProtKB:P35613] synonym: "5F7" EXACT [UniProtKB:P35613] synonym: "CD147 antigen" EXACT [UniProtKB:P35613] synonym: "Collagenase stimulatory factor" EXACT [UniProtKB:P35613] synonym: "EMMPRIN" EXACT [UniProtKB:P35613] synonym: "Extracellular matrix metalloproteinase inducer" EXACT [UniProtKB:P35613] synonym: "Leukocyte activation antigen M6" EXACT [UniProtKB:P35613] synonym: "OK blood group antigen" EXACT [UniProtKB:P35613] synonym: "TCSF" EXACT [UniProtKB:P35613] synonym: "Tumor cell-derived collagenase stimulatory factor" EXACT [UniProtKB:P35613] xref: EMBL:AAA68936.1 xref: EMBL:AAA91084.1 xref: EMBL:AAB41120.1 xref: EMBL:AAC33279.1 xref: EMBL:AAD10704.1 xref: EMBL:AAH09040.1 xref: EMBL:AAN40694.1 xref: EMBL:AAQ88480.1 xref: EMBL:AAX20110.1 xref: EMBL:BAA08109.1 xref: EMBL:BAB88938.1 xref: EMBL:BAC76828.1 xref: EMBL:CAA45716.1 xref: UniProtKB:P35613 xref: UniProtKB:Q7Z796 xref: UniProtKB:Q8IZL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017128 ! BSG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015634 ! bsg-pdlim7 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0063733 ! BASI_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0063734 ! BASI_HUMAN-Phosphoserine368 [Term] id: CCO:B0055297 name: TIMP3_HUMAN def: "Metalloproteinase inhibitor 3 precursor" [UniProtKB:P35625] synonym: "Protein MIG-5" EXACT [UniProtKB:P35625] synonym: "TIMP-3" EXACT [UniProtKB:P35625] synonym: "Tissue inhibitor of metalloproteinases 3" EXACT [UniProtKB:P35625] xref: EMBL:AAA17672.1 xref: EMBL:AAA21815.1 xref: EMBL:AAB07547.1 xref: EMBL:AAB17602.1 xref: EMBL:AAB34532.1 xref: EMBL:AAB60373.1 xref: EMBL:AAC50393.1 xref: EMBL:AAH14277.1 xref: EMBL:AAP35494.1 xref: EMBL:CAA53813.1 xref: EMBL:CAA82918.1 xref: EMBL:CAG30479.1 xref: EMBL:CAI17996.1 xref: EMBL:CAI20115.1 xref: UniProtKB:P35625 xref: UniProtKB:Q5THV4 xref: UniProtKB:Q9UC74 xref: UniProtKB:Q9UGS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020274 ! TIMP3_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001771 ! metalloendopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0055298 name: ARBK2_HUMAN def: "Beta-adrenergic receptor kinase 2" [UniProtKB:P35626] synonym: "Beta-ARK-2" EXACT [UniProtKB:P35626] synonym: "EC 2.7.11.15" EXACT [UniProtKB:P35626] synonym: "G-protein-coupled receptor kinase 3" EXACT [UniProtKB:P35626] xref: EMBL:CAA48870.1 xref: EMBL:CAB45657.1 xref: UniProtKB:P35626 xref: UniProtKB:Q9UGW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017000 ! ADRBK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006998 ! beta-adrenergic receptor kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055299 name: HNF1B_HUMAN def: "Hepatocyte nuclear factor 1-beta" [UniProtKB:P35680] synonym: "HNF-1-beta" EXACT [UniProtKB:P35680] synonym: "HNF-1B" EXACT [UniProtKB:P35680] synonym: "Homeoprotein LFB3" EXACT [UniProtKB:P35680] synonym: "TCF-2" EXACT [UniProtKB:P35680] synonym: "Transcription factor 2" EXACT [UniProtKB:P35680] synonym: "Variant hepatic nuclear factor 1" EXACT [UniProtKB:P35680] synonym: "vHNF1" EXACT [UniProtKB:P35680] xref: EMBL:AAC63388.1 xref: EMBL:AAH17714.1 xref: EMBL:CAA41652.1 xref: EMBL:CAB59223.1 xref: UniProtKB:P35680 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018149 ! HNF1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0066850 ! HNF1B_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0066851 ! HNF1B_HUMAN-Phosphoserine80 [Term] id: CCO:B0055300 name: SOX5_HUMAN def: "Transcription factor SOX-5" [UniProtKB:P35711] xref: EMBL:AAB49537.1 xref: EMBL:AAH29220.2 xref: EMBL:AAH35227.1 xref: EMBL:AAH47665.2 xref: EMBL:AAH60773.1 xref: EMBL:BAB85048.1 xref: EMBL:BAC05353.1 xref: EMBL:BAC16233.1 xref: EMBL:BAC16234.1 xref: EMBL:BAC16235.1 xref: EMBL:BAC16236.1 xref: EMBL:CAA46613.1 xref: UniProtKB:P35711 xref: UniProtKB:Q86UK8 xref: UniProtKB:Q8J017 xref: UniProtKB:Q8J018 xref: UniProtKB:Q8J019 xref: UniProtKB:Q8J020 xref: UniProtKB:Q8N1D9 xref: UniProtKB:Q8N7E0 xref: UniProtKB:Q8TEA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019991 ! SOX5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070752 ! SOX5_HUMAN-Phosphothreonine108 relationship: transforms_into CCO:B0070753 ! SOX5_HUMAN-Phosphoserine414 [Term] id: CCO:B0055301 name: SOX6_HUMAN def: "Transcription factor SOX-6" [UniProtKB:P35712] xref: EMBL:AAH47064.2 xref: EMBL:AAK26115.1 xref: EMBL:AAK26243.1 xref: EMBL:AAK26244.1 xref: EMBL:CAA46614.1 xref: EMBL:CAB66714.1 xref: EMBL:EAW68458.1 xref: UniProtKB:P35712 xref: UniProtKB:Q86VX7 xref: UniProtKB:Q9BXQ3 xref: UniProtKB:Q9BXQ4 xref: UniProtKB:Q9BXQ5 xref: UniProtKB:Q9H0I8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019992 ! SOX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055302 name: ZNF93_HUMAN def: "Zinc finger protein 93" [UniProtKB:P35789] synonym: "Zinc finger protein 505" EXACT [UniProtKB:P35789] synonym: "Zinc finger protein HTF34" EXACT [UniProtKB:P35789] xref: EMBL:AAA83548.1 xref: EMBL:AAD22981.1 xref: EMBL:BAB14093.1 xref: EMBL:BAC04764.1 xref: UniProtKB:A6NMY2 xref: UniProtKB:P35789 xref: UniProtKB:Q8N8Q4 xref: UniProtKB:Q9H9X5 xref: UniProtKB:Q9Y2N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020995 ! ZNF93_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055303 name: PDE6B_HUMAN def: "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor" [UniProtKB:P35913] synonym: "EC 3.1.4.35" EXACT [UniProtKB:P35913] synonym: "GMP-PDE beta" EXACT [UniProtKB:P35913] xref: EMBL:AAB22690.1 xref: EMBL:AAH00249.1 xref: EMBL:CAA44569.1 xref: EMBL:CAA46932.1 xref: EMBL:CAA62215.1 xref: UniProtKB:P35913 xref: UniProtKB:Q9BWH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019344 ! PDE6B_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006858 ! 3',5'-cyclic-GMP phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055304 name: VGFR3_HUMAN def: "Vascular endothelial growth factor receptor 3 precursor" [UniProtKB:P35916] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P35916] synonym: "Tyrosine-protein kinase receptor FLT4" EXACT [UniProtKB:P35916] synonym: "VEGFR-3" EXACT [UniProtKB:P35916] xref: EMBL:AAA85215.1 xref: EMBL:CAA48290.1 xref: EMBL:CAA49505.1 xref: UniProtKB:P35916 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020444 ! FLT4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019317 ! flt4-kdr physical interaction relationship: participates_in CCO:I0019318 ! flt4-kdr-1 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway relationship: transforms_into CCO:B0071795 ! VGFR3_HUMAN-Phosphotyrosine1063 relationship: transforms_into CCO:B0071796 ! VGFR3_HUMAN-Phosphotyrosine1068 [Term] id: CCO:B0055305 name: VGFR2_HUMAN def: "Vascular endothelial growth factor receptor 2 precursor" [UniProtKB:P35968] synonym: "CD309 antigen" EXACT [UniProtKB:P35968] synonym: "EC 2.7.10.1" EXACT [UniProtKB:P35968] synonym: "Kinase insert domain receptor" EXACT [UniProtKB:P35968] synonym: "Protein-tyrosine kinase receptor Flk-1" EXACT [UniProtKB:P35968] synonym: "VEGFR-2" EXACT [UniProtKB:P35968] xref: EMBL:AAA59459.1 xref: EMBL:AAB88005.1 xref: EMBL:AAC16450.1 xref: EMBL:CAA43837.1 xref: EMBL:CAA61916.1 xref: UniProtKB:O60723 xref: UniProtKB:P35968 xref: UniProtKB:Q14178 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020443 ! KDR_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017809 ! kdr-nrp1 physical interaction relationship: participates_in CCO:I0019317 ! flt4-kdr physical interaction relationship: participates_in CCO:I0019318 ! flt4-kdr-1 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0071793 ! VGFR2_HUMAN-Phosphotyrosine1054 relationship: transforms_into CCO:B0071794 ! VGFR2_HUMAN-Phosphotyrosine1059 [Term] id: CCO:B0055306 name: TCF7_HUMAN def: "Transcription factor 7" [UniProtKB:P36402] synonym: "T-cell factor 1" EXACT [UniProtKB:P36402] synonym: "T-cell-specific transcription factor 1" EXACT [UniProtKB:P36402] synonym: "TCF-1" EXACT [UniProtKB:P36402] xref: EMBL:AAF00616.1 xref: EMBL:AAH48769.1 xref: EMBL:AAH72023.1 xref: EMBL:CAA42526.1 xref: EMBL:CAA42527.1 xref: EMBL:CAA42528.1 xref: EMBL:CAA87439.1 xref: EMBL:CAA87440.1 xref: EMBL:CAA87441.1 xref: EMBL:CAA87442.1 xref: EMBL:CAB56795.1 xref: EMBL:EAW62277.1 xref: UniProtKB:P36402 xref: UniProtKB:Q86WR9 xref: UniProtKB:Q9UKI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020217 ! TCF7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0055307 name: ARL2_HUMAN def: "ADP-ribosylation factor-like protein 2" [UniProtKB:P36404] xref: EMBL:AAC37606.1 xref: EMBL:AAH02530.1 xref: EMBL:AAM12602.1 xref: UniProtKB:P36404 xref: UniProtKB:Q9BUK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017035 ! ARL2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015843 ! arl2-pde6d physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055308 name: ARD1_HUMAN def: "GTP-binding protein ARD-1" [UniProtKB:P36406] synonym: "ADP-ribosylation factor domain-containing protein 1" EXACT [UniProtKB:P36406] synonym: "RING finger protein 46" EXACT [UniProtKB:P36406] synonym: "Tripartite motif-containing protein 23" EXACT [UniProtKB:P36406] xref: EMBL:AAA35940.1 xref: EMBL:AAG50176.1 xref: EMBL:AAG50177.1 xref: EMBL:AAG50178.1 xref: EMBL:AAH22510.1 xref: UniProtKB:P36406 xref: UniProtKB:Q9BZY4 xref: UniProtKB:Q9BZY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017001 ! TRIM23_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004046 ! GDP binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0014959 ! ribc2-trim23 physical interaction relationship: participates_in CCO:I0014992 ! trim23-trim23 physical interaction relationship: participates_in CCO:I0015097 ! gem-trim23 physical interaction relationship: participates_in CCO:I0015201 ! sf1-trim23 physical interaction relationship: participates_in CCO:I0015231 ! pom121-trim23 physical interaction relationship: participates_in CCO:I0015254 ! gga2-trim23 physical interaction relationship: participates_in CCO:I0015473 ! lnx-trim23 physical interaction relationship: participates_in CCO:I0015577 ! trim23-znf581 physical interaction relationship: participates_in CCO:I0015752 ! trim23-znf250 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055309 name: ZNF76_HUMAN def: "Zinc finger protein 76" [UniProtKB:P36508] synonym: "Zinc finger protein 523" EXACT [UniProtKB:P36508] xref: EMBL:AAA98739.1 xref: EMBL:AAH00133.1 xref: EMBL:AAH02549.1 xref: EMBL:AAP35980.1 xref: UniProtKB:P36508 xref: UniProtKB:Q9BQB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020985 ! ZNF76_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter [Term] id: CCO:B0055310 name: ACHA7_HUMAN def: "Neuronal acetylcholine receptor subunit alpha-7 precursor" [UniProtKB:P36544] xref: EMBL:AAA83561.1 xref: EMBL:AAB40114.1 xref: EMBL:AAK19515.1 xref: EMBL:AAK68111.1 xref: EMBL:CAA49778.1 xref: EMBL:CAA69697.1 xref: EMBL:CAA80672.1 xref: UniProtKB:P36544 xref: UniProtKB:Q15826 xref: UniProtKB:Q96RH2 xref: UniProtKB:Q99555 xref: UniProtKB:Q9BXH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016892 ! CHRNA7_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0001765 ! adenylate cyclase binding relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0002995 ! toxin binding relationship: has_function CCO:F0003552 ! chloride channel regulator activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0005634 ! acetylcholine binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000740 ! postsynaptic density relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001430 ! asymmetric synapse relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0001729 ! dendritic spine relationship: located_in CCO:C0001730 ! dendritic shaft relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:I0017903 ! app-chrna7-1 colocalization relationship: participates_in CCO:I0018080 ! app-chrna7-3 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001080 ! regulation of norepinephrine secretion relationship: participates_in CCO:P0001563 ! regulation of synaptic transmission, dopaminergic [Term] id: CCO:B0055311 name: ARRC_HUMAN def: "Arrestin-C" [UniProtKB:P36575] synonym: "C-arrestin" EXACT [UniProtKB:P36575] synonym: "cArr" EXACT [UniProtKB:P36575] synonym: "Cone arrestin" EXACT [UniProtKB:P36575] synonym: "Retinal cone arrestin-3" EXACT [UniProtKB:P36575] synonym: "X-arrestin" EXACT [UniProtKB:P36575] xref: EMBL:AAB84302.1 xref: EMBL:AAC27524.1 xref: EMBL:AAC78395.1 xref: EMBL:AAH12096.1 xref: EMBL:CAG33130.1 xref: EMBL:CAI41490.1 xref: EMBL:CAI41491.1 xref: UniProtKB:P36575 xref: UniProtKB:Q5JT23 xref: UniProtKB:Q5JT24 xref: UniProtKB:Q6IBF5 xref: UniProtKB:Q96EN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017051 ! ARR3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020238 ! arr3-capns1 physical interaction relationship: participates_in CCO:I0020239 ! arr3-rnase6 physical interaction relationship: participates_in CCO:I0020512 ! arr3-rcor2 physical interaction relationship: participates_in CCO:I0020513 ! arr3-map2k7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055312 name: GNL1_HUMAN def: "Guanine nucleotide-binding protein-like 1" [UniProtKB:P36915] synonym: "GTP-binding protein HSR1" EXACT [UniProtKB:P36915] xref: EMBL:AAA66492.1 xref: EMBL:AAH13959.1 xref: EMBL:AAH18366.1 xref: EMBL:AAP35294.1 xref: EMBL:CAI17831.1 xref: EMBL:CAI18152.1 xref: EMBL:CAI18558.1 xref: EMBL:CAM26012.1 xref: UniProtKB:P36915 xref: UniProtKB:Q96CT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017946 ! GNL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066492 ! GNL1_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0066493 ! GNL1_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0066494 ! GNL1_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0066495 ! GNL1_HUMAN-Phosphothreonine48 relationship: transforms_into CCO:B0066496 ! GNL1_HUMAN-Phosphothreonine50 relationship: transforms_into CCO:B0066497 ! GNL1_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0066498 ! GNL1_HUMAN-Phosphoserine68 relationship: transforms_into CCO:B0066499 ! GNL1_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0066500 ! GNL1_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0066501 ! GNL1_HUMAN-Phosphoserine562 relationship: transforms_into CCO:B0066502 ! GNL1_HUMAN-Phosphoserine563 [Term] id: CCO:B0055313 name: TNR3_HUMAN def: "Tumor necrosis factor receptor superfamily member 3 precursor" [UniProtKB:P36941] synonym: "Lymphotoxin-beta receptor" EXACT [UniProtKB:P36941] synonym: "Tumor necrosis factor C receptor" EXACT [UniProtKB:P36941] synonym: "Tumor necrosis factor receptor 2-related protein" EXACT [UniProtKB:P36941] xref: EMBL:AAA36757.1 xref: EMBL:AAH26262.1 xref: UniProtKB:P36941 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020319 ! LTBR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055314 name: RPB9_HUMAN def: "DNA-directed RNA polymerase II subunit RPB9" [UniProtKB:P36954] synonym: "DNA-directed RNA polymerase II 14.5 kDa polypeptide" EXACT [UniProtKB:P36954] synonym: "DNA-directed RNA polymerase II subunit I" EXACT [UniProtKB:P36954] synonym: "RNA polymerase II subunit B9" EXACT [UniProtKB:P36954] synonym: "RPB14.5" EXACT [UniProtKB:P36954] xref: EMBL:AAB51181.1 xref: EMBL:AAH17112.1 xref: EMBL:AAH67794.1 xref: EMBL:CAA80649.1 xref: UniProtKB:P36954 xref: UniProtKB:Q6NW05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019780 ! POLR2I_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070158 ! RPB9_HUMAN-Phosphoserine73 [Term] id: CCO:B0055315 name: PEDF_HUMAN def: "Pigment epithelium-derived factor precursor" [UniProtKB:P36955] synonym: "EPC-1" EXACT [UniProtKB:P36955] synonym: "PEDF" EXACT [UniProtKB:P36955] synonym: "Serpin-F1" EXACT [UniProtKB:P36955] xref: EMBL:AAA60058.1 xref: EMBL:AAA84914.1 xref: EMBL:AAA93524.1 xref: EMBL:AAB38685.1 xref: EMBL:AAH00522.1 xref: EMBL:AAH13984.1 xref: EMBL:AAK92491.1 xref: EMBL:AAP35886.1 xref: UniProtKB:P36955 xref: UniProtKB:Q13236 xref: UniProtKB:Q96CT1 xref: UniProtKB:Q96R01 xref: UniProtKB:Q9BWA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019360 ! SERPINF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002947 ! positive regulation of neurogenesis relationship: transforms_into CCO:B0069207 ! PEDF_HUMAN-Pyrrolidone carboxylic acid20 relationship: transforms_into CCO:B0069208 ! PEDF_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0069209 ! PEDF_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0069210 ! PEDF_HUMAN-Phosphoserine227 [Term] id: CCO:B0055316 name: SRP14_HUMAN def: "Signal recognition particle 14 kDa protein" [UniProtKB:P37108] synonym: "18 kDa Alu RNA-binding protein" EXACT [UniProtKB:P37108] synonym: "SRP14" EXACT [UniProtKB:P37108] xref: EMBL:AAA59066.1 xref: EMBL:AAH35495.1 xref: EMBL:AAH71716.1 xref: EMBL:AAI00032.1 xref: EMBL:CAA51838.1 xref: UniProtKB:P37108 xref: UniProtKB:Q6B0K5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020039 ! SRP14_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001826 ! 7S RNA binding relationship: has_function CCO:F0004604 ! endoplasmic reticulum signal peptide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000367 ! signal recognition particle, endoplasmic reticulum targeting relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002002 ! signal recognition particle relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0020612 ! nsfl1c-srp14 physical interaction relationship: participates_in CCO:P0002601 ! negative regulation of translational elongation [Term] id: CCO:B0055317 name: ZEB1_HUMAN def: "Zinc finger E-box-binding homeobox 1" [UniProtKB:P37275] synonym: "Negative regulator of IL2" EXACT [UniProtKB:P37275] synonym: "NIL-2-A zinc finger protein" EXACT [UniProtKB:P37275] synonym: "Transcription factor 8" EXACT [UniProtKB:P37275] xref: EMBL:AAA20602.1 xref: EMBL:BAA03646.1 xref: EMBL:CAH74132.1 xref: EMBL:CAI12550.1 xref: EMBL:CAI15108.1 xref: EMBL:CAI17320.1 xref: EMBL:EAW85989.1 xref: UniProtKB:P37275 xref: UniProtKB:Q12924 xref: UniProtKB:Q13800 xref: UniProtKB:Q5T968 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020576 ! ZEB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0071987 ! ZEB1_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0071988 ! ZEB1_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0071989 ! ZEB1_HUMAN-Phosphoserine322 relationship: transforms_into CCO:B0071990 ! ZEB1_HUMAN-Phosphoserine646 relationship: transforms_into CCO:B0071991 ! ZEB1_HUMAN-Phosphoserine679 [Term] id: CCO:B0055318 name: V1AR_HUMAN def: "Vasopressin V1a receptor" [UniProtKB:P37288] synonym: "Antidiuretic hormone receptor 1a" EXACT [UniProtKB:P37288] synonym: "AVPR V1a" EXACT [UniProtKB:P37288] synonym: "V1aR" EXACT [UniProtKB:P37288] synonym: "Vascular/hepatic-type arginine vasopressin receptor" EXACT [UniProtKB:P37288] xref: EMBL:AAA62271.1 xref: EMBL:AAB19232.1 xref: EMBL:AAC51861.1 xref: EMBL:AAC60638.1 xref: EMBL:AAD17891.1 xref: EMBL:AAH74803.1 xref: EMBL:AAH74804.1 xref: EMBL:AAP84363.1 xref: UniProtKB:P37288 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020428 ! AVPR1A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001338 ! vasopressin receptor activity relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0003529 ! peptide hormone binding relationship: has_function CCO:F0004902 ! V1A vasopressin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: transforms_into CCO:B0071771 ! V1AR_HUMAN-Phosphoserine404 [Term] id: CCO:B0055319 name: INGR2_HUMAN def: "Interferon-gamma receptor beta chain precursor" [UniProtKB:P38484] synonym: "AF-1" EXACT [UniProtKB:P38484] synonym: "Interferon-gamma receptor accessory factor 1" EXACT [UniProtKB:P38484] synonym: "Interferon-gamma transducer 1" EXACT [UniProtKB:P38484] xref: EMBL:AAA16955.1 xref: EMBL:AAA16956.1 xref: EMBL:AAC52066.1 xref: EMBL:AAH03624.1 xref: EMBL:AAT45458.1 xref: UniProtKB:P38484 xref: UniProtKB:Q9BTL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018286 ! IFNGR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0067115 ! INGR2_HUMAN-Phosphoserine198 [Term] id: CCO:B0055320 name: IF4A3_HUMAN def: "Eukaryotic initiation factor 4A-III" [UniProtKB:P38919] synonym: "ATP-dependent RNA helicase DDX48" EXACT [UniProtKB:P38919] synonym: "ATP-dependent RNA helicase eIF4A-3" EXACT [UniProtKB:P38919] synonym: "DEAD box protein 48" EXACT [UniProtKB:P38919] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P38919] synonym: "Eukaryotic initiation factor 4A-like NUK-34" EXACT [UniProtKB:P38919] synonym: "Eukaryotic translation initiation factor 4A isoform 3" EXACT [UniProtKB:P38919] synonym: "hNMP 265" EXACT [UniProtKB:P38919] synonym: "Nuclear matrix protein 265" EXACT [UniProtKB:P38919] xref: EMBL:AAH03662.1 xref: EMBL:AAH04386.1 xref: EMBL:AAH11151.1 xref: EMBL:BAA04879.2 xref: EMBL:CAA56074.1 xref: UniProtKB:P38919 xref: UniProtKB:Q15033 xref: UniProtKB:Q96A18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018226 ! EIF4A3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001745 ! poly(A) binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017741 ! rbm8a-ddx48-1 physical interaction relationship: participates_in CCO:I0017742 ! magoh-ddx48-1 physical interaction relationship: participates_in CCO:I0017948 ! casc3-ddx48 physical interaction relationship: participates_in CCO:I0017949 ! casc3-ddx48-1 physical interaction relationship: participates_in CCO:I0018062 ! magoh-ddx48-2 physical interaction relationship: participates_in CCO:I0018063 ! rbm8a-ddx48-2 physical interaction relationship: participates_in CCO:I0018317 ! ddx48-thoc4-1 direct interaction relationship: participates_in CCO:I0018484 ! ddx48-eif4gi physical interaction relationship: participates_in CCO:I0018578 ! btz-eif4aiii physical interaction relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: transforms_into CCO:B0067023 ! IF4A3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0067024 ! IF4A3_HUMAN-Phosphothreonine163 [Term] id: CCO:B0055321 name: SMBP2_HUMAN def: "DNA-binding protein SMUBP-2" [UniProtKB:P38935] synonym: "ATP-dependent helicase IGHMBP2" EXACT [UniProtKB:P38935] synonym: "EC 3.6.1.-" EXACT [UniProtKB:P38935] synonym: "GF-1" EXACT [UniProtKB:P38935] synonym: "Glial factor 1" EXACT [UniProtKB:P38935] synonym: "Immunoglobulin mu-binding protein 2" EXACT [UniProtKB:P38935] synonym: "SMUBP-2" EXACT [UniProtKB:P38935] xref: EMBL:AAA53082.1 xref: EMBL:AAA58611.1 xref: EMBL:AAA70430.1 xref: UniProtKB:P38935 xref: UniProtKB:Q00443 xref: UniProtKB:Q14177 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019945 ! IGHMBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017326 ! lsm8-ighmbp2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070612 ! SMBP2_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0070613 ! SMBP2_HUMAN-Phosphoserine656 [Term] id: CCO:B0055322 name: COIA1_HUMAN def: "Collagen alpha-1(XVIII) chain precursor" [UniProtKB:P39060] xref: EMBL:AAA51864.1 xref: EMBL:AAC39658.1 xref: EMBL:AAC39659.1 xref: EMBL:AAF01310.1 xref: EMBL:AAH33715.1 xref: EMBL:AAH63833.1 xref: EMBL:AAK50626.1 xref: EMBL:AAL37720.1 xref: EMBL:AAR83296.1 xref: EMBL:AAR83297.1 xref: EMBL:AAR83298.1 xref: EMBL:CAB90482.1 xref: UniProtKB:P39060 xref: UniProtKB:Q58EX6 xref: UniProtKB:Q6RZ39 xref: UniProtKB:Q6RZ40 xref: UniProtKB:Q6RZ41 xref: UniProtKB:Q8N4S4 xref: UniProtKB:Q8WXI5 xref: UniProtKB:Q96T70 xref: UniProtKB:Q9UK38 xref: UniProtKB:Q9Y6Q7 xref: UniProtKB:Q9Y6Q8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017433 ! COL18A1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000205 ! collagen relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055323 name: GDNF_HUMAN def: "Glial cell line-derived neurotrophic factor precursor" [UniProtKB:P39905] synonym: "Astrocyte-derived trophic factor" EXACT [UniProtKB:P39905] synonym: "ATF" EXACT [UniProtKB:P39905] synonym: "hGDNF" EXACT [UniProtKB:P39905] xref: EMBL:AAA67910.1 xref: EMBL:AAC98782.1 xref: EMBL:AAD43139.1 xref: EMBL:AAH69119.1 xref: EMBL:AAH69369.1 xref: EMBL:AAI28109.1 xref: EMBL:AAI28110.1 xref: EMBL:AAL11017.1 xref: EMBL:CAA05074.1 xref: EMBL:CAA05075.1 xref: EMBL:CAA05076.1 xref: EMBL:CAA05077.1 xref: EMBL:CAA05078.1 xref: EMBL:CAG46721.1 xref: UniProtKB:O95448 xref: UniProtKB:O95449 xref: UniProtKB:O95986 xref: UniProtKB:P39905 xref: UniProtKB:Q6FH33 xref: UniProtKB:Q96L44 xref: UniProtKB:Q9UD32 xref: UniProtKB:Q9UD33 xref: UniProtKB:Q9UMV2 xref: UniProtKB:Q9UP67 xref: UniProtKB:Q9UP97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017912 ! GDNF_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis [Term] id: CCO:B0055324 name: CAPG_HUMAN def: "Macrophage-capping protein" [UniProtKB:P40121] synonym: "Actin regulatory protein CAP-G" EXACT [UniProtKB:P40121] xref: EMBL:AAA59570.1 xref: EMBL:AAA92670.1 xref: EMBL:AAH00728.1 xref: EMBL:AAH14549.1 xref: EMBL:AAY24128.1 xref: UniProtKB:P40121 xref: UniProtKB:Q53SA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017225 ! CAPG_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000542 ! F-actin capping protein complex relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping [Term] id: CCO:B0055325 name: ADCY8_HUMAN def: "Adenylate cyclase type 8" [UniProtKB:P40145] synonym: "Adenylate cyclase type VIII" EXACT [UniProtKB:P40145] synonym: "Adenylyl cyclase 8" EXACT [UniProtKB:P40145] synonym: "ATP pyrophosphate-lyase 8" EXACT [UniProtKB:P40145] synonym: "Ca(2+)/calmodulin-activated adenylyl cyclase" EXACT [UniProtKB:P40145] synonym: "EC 4.6.1.1" EXACT [UniProtKB:P40145] xref: EMBL:AAA35523.2 xref: EMBL:CAA84552.1 xref: UniProtKB:P40145 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016913 ! ADCY8_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0001817 ! calcium- and calmodulin-responsive adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0055326 name: TXLNA_HUMAN def: "Alpha-taxilin" [UniProtKB:P40222] xref: EMBL:AAH29686.1 xref: EMBL:AAH46565.1 xref: EMBL:AAH80578.1 xref: EMBL:AAI03824.1 xref: EMBL:AAI03825.1 xref: EMBL:AAO42465.1 xref: EMBL:CAD89951.1 xref: EMBL:CAD89952.1 xref: EMBL:CAD91138.1 xref: EMBL:CAI22055.1 xref: UniProtKB:P40222 xref: UniProtKB:Q5TFJ6 xref: UniProtKB:Q66K62 xref: UniProtKB:Q86T54 xref: UniProtKB:Q86T85 xref: UniProtKB:Q86T86 xref: UniProtKB:Q86Y86 xref: UniProtKB:Q86YW3 xref: UniProtKB:Q8N2Y3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020389 ! TXLNA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017221 ! ikbkg-il14 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0071631 ! TXLNA_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0071632 ! TXLNA_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0071633 ! TXLNA_HUMAN-Phosphoserine515 [Term] id: CCO:B0055327 name: TPOR_HUMAN def: "Thrombopoietin receptor precursor" [UniProtKB:P40238] synonym: "C-mpl" EXACT [UniProtKB:P40238] synonym: "CD110 antigen" EXACT [UniProtKB:P40238] synonym: "Myeloproliferative leukemia protein" EXACT [UniProtKB:P40238] synonym: "TPO-R" EXACT [UniProtKB:P40238] xref: EMBL:AAA69971.1 xref: EMBL:AAA69972.1 xref: EMBL:AAB08424.1 xref: EMBL:AAB08425.1 xref: UniProtKB:P40238 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020329 ! MPL_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055328 name: CD79B_HUMAN def: "B-cell antigen receptor complex-associated protein beta-chain precursor" [UniProtKB:P40259] synonym: "B-cell-specific glycoprotein B29" EXACT [UniProtKB:P40259] synonym: "CD79b antigen" EXACT [UniProtKB:P40259] synonym: "IG-beta" EXACT [UniProtKB:P40259] synonym: "Immunoglobulin-associated B29 protein" EXACT [UniProtKB:P40259] xref: EMBL:AAA58387.1 xref: EMBL:AAA64459.1 xref: EMBL:AAA72424.1 xref: EMBL:AAB24822.2 xref: EMBL:AAC60654.1 xref: EMBL:AAH02975.2 xref: EMBL:AAH32651.1 xref: EMBL:BAD96674.1 xref: EMBL:BAD96930.1 xref: EMBL:CAA58522.1 xref: UniProtKB:P40259 xref: UniProtKB:Q53FS2 xref: UniProtKB:Q9BU06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017309 ! CD79B_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0055329 name: PBX1_HUMAN def: "Pre-B-cell leukemia transcription factor 1" [UniProtKB:P40424] synonym: "Homeobox protein PBX1" EXACT [UniProtKB:P40424] synonym: "Homeobox protein PRL" EXACT [UniProtKB:P40424] xref: EMBL:AAA36764.1 xref: EMBL:AAA60031.1 xref: EMBL:AAG30941.1 xref: EMBL:AAI01579.1 xref: EMBL:CAH73499.1 xref: EMBL:CAI14854.1 xref: EMBL:CAI14908.1 xref: UniProtKB:P40424 xref: UniProtKB:Q5T488 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019314 ! PBX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017279 ! hoxb1-pbx1-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055330 name: PBX3_HUMAN def: "Pre-B-cell leukemia transcription factor 3" [UniProtKB:P40426] synonym: "Homeobox protein PBX3" EXACT [UniProtKB:P40426] xref: EMBL:AAH94883.1 xref: EMBL:AAL09477.1 xref: EMBL:AAL09478.1 xref: EMBL:CAA42502.1 xref: EMBL:CAH73695.1 xref: EMBL:CAI40243.1 xref: UniProtKB:P40426 xref: UniProtKB:Q5VXL3 xref: UniProtKB:Q96PF9 xref: UniProtKB:Q96PG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019315 ! PBX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069150 ! PBX3_HUMAN-Phosphoserine121 [Term] id: CCO:B0055331 name: ARL4A_HUMAN def: "ADP-ribosylation factor-like protein 4A" [UniProtKB:P40617] xref: EMBL:AAB39713.1 xref: EMBL:AAH01111.1 xref: EMBL:AAH03027.1 xref: EMBL:AAH39123.1 xref: EMBL:AAM12604.1 xref: UniProtKB:P40617 xref: UniProtKB:P80418 xref: UniProtKB:Q49AF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017036 ! ARL4A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055332 name: IL15_HUMAN def: "Interleukin-15 precursor" [UniProtKB:P40933] synonym: "IL-15" EXACT [UniProtKB:P40933] xref: EMBL:AAA21551.1 xref: EMBL:AAB97518.1 xref: EMBL:AAH18149.1 xref: EMBL:AAI00964.1 xref: EMBL:CAA62616.1 xref: EMBL:CAA63913.1 xref: EMBL:CAA63914.1 xref: EMBL:CAA71044.1 xref: EMBL:CAA86100.1 xref: UniProtKB:O00440 xref: UniProtKB:O43512 xref: UniProtKB:P40933 xref: UniProtKB:Q495Z8 xref: UniProtKB:Q93058 xref: UniProtKB:Q9UBA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018250 ! IL15_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: participates_in CCO:I0018381 ! il15-il15ra physical interaction relationship: participates_in CCO:I0018382 ! il15-il15ra-1 physical interaction relationship: participates_in CCO:I0018383 ! il15-il15ra-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055333 name: LEP_HUMAN def: "Leptin precursor" [UniProtKB:P41159] synonym: "Obese protein" EXACT [UniProtKB:P41159] synonym: "Obesity factor" EXACT [UniProtKB:P41159] xref: EMBL:AAA60470.1 xref: EMBL:AAB63507.1 xref: EMBL:AAC31660.1 xref: EMBL:AAC50400.1 xref: EMBL:AAH60830.1 xref: EMBL:AAH69452.1 xref: EMBL:AAH69527.1 xref: EMBL:AAX81413.1 xref: EMBL:BAA08448.1 xref: EMBL:BAA09787.1 xref: EMBL:BAA09839.1 xref: UniProtKB:O15158 xref: UniProtKB:P41159 xref: UniProtKB:Q56A88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018473 ! LEP_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002453 ! positive regulation of myeloid cell differentiation [Term] id: CCO:B0055334 name: ETV5_HUMAN def: "ETS translocation variant 5" [UniProtKB:P41161] synonym: "Ets-related protein ERM" EXACT [UniProtKB:P41161] xref: EMBL:AAH07333.1 xref: EMBL:AAP35359.1 xref: EMBL:CAA53778.1 xref: EMBL:CAA65246.1 xref: EMBL:CAG33048.1 xref: EMBL:EAW78200.1 xref: UniProtKB:A6NH46 xref: UniProtKB:P41161 xref: UniProtKB:Q6IBN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017741 ! ETV5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0055335 name: CASR_HUMAN def: "Extracellular calcium-sensing receptor precursor" [UniProtKB:P41180] synonym: "CaSR" EXACT [UniProtKB:P41180] synonym: "Parathyroid Cell calcium-sensing receptor" EXACT [UniProtKB:P41180] synonym: "PCaR1" EXACT [UniProtKB:P41180] xref: EMBL:AAA86503.1 xref: EMBL:AAA86504.1 xref: EMBL:AAB29413.2 xref: EMBL:AAB29414.1 xref: EMBL:AAB29415.1 xref: EMBL:AAB35262.2 xref: EMBL:AAB46873.1 xref: EMBL:AAD14370.1 xref: EMBL:AAI05000.1 xref: EMBL:AAI12237.1 xref: EMBL:AAY68221.1 xref: EMBL:BAA09453.1 xref: EMBL:CAA56990.1 xref: UniProtKB:P41180 xref: UniProtKB:Q13912 xref: UniProtKB:Q16108 xref: UniProtKB:Q16109 xref: UniProtKB:Q16110 xref: UniProtKB:Q16379 xref: UniProtKB:Q2M1T0 xref: UniProtKB:Q4PJ19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017241 ! CASR_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0055336 name: WNT5A_HUMAN def: "Protein Wnt-5a precursor" [UniProtKB:P41221] xref: EMBL:AAA16842.1 xref: EMBL:AAH64694.1 xref: EMBL:BAF83064.1 xref: EMBL:BAF83558.1 xref: EMBL:EAW65310.1 xref: UniProtKB:A8K4A4 xref: UniProtKB:P41221 xref: UniProtKB:Q6P278 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020490 ! WNT5A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0055337 name: JAD1C_HUMAN def: "Histone demethylase JARID1C" [UniProtKB:P41229] synonym: "EC 1.14.11.-" EXACT [UniProtKB:P41229] synonym: "Jumonji/ARID domain-containing protein 1C" EXACT [UniProtKB:P41229] synonym: "Protein SmcX" EXACT [UniProtKB:P41229] synonym: "Protein Xe169" EXACT [UniProtKB:P41229] xref: EMBL:AAA61302.1 xref: EMBL:AAH54499.1 xref: EMBL:CAA82758.1 xref: EMBL:CAI39836.1 xref: EMBL:CAI39837.1 xref: EMBL:CAI39838.1 xref: UniProtKB:P41229 xref: UniProtKB:Q5JUX3 xref: UniProtKB:Q5JUX4 xref: UniProtKB:Q5JUX5 xref: UniProtKB:Q7Z5S5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018354 ! JARID1C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067186 ! JAD1C_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0067187 ! JAD1C_HUMAN-Phosphoserine1359 [Term] id: CCO:B0055338 name: P2RY2_HUMAN def: "P2Y purinoceptor 2" [UniProtKB:P41231] synonym: "ATP receptor" EXACT [UniProtKB:P41231] synonym: "P2U purinoceptor 1" EXACT [UniProtKB:P41231] synonym: "P2U1" EXACT [UniProtKB:P41231] synonym: "P2Y2" EXACT [UniProtKB:P41231] synonym: "Purinergic receptor" EXACT [UniProtKB:P41231] xref: EMBL:AAC04923.1 xref: EMBL:AAH12104.1 xref: EMBL:AAH28135.1 xref: EMBL:AAN01279.1 xref: UniProtKB:P41231 xref: UniProtKB:Q96EM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019266 ! P2RY2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0055339 name: IPP2_HUMAN def: "Protein phosphatase inhibitor 2" [UniProtKB:P41236] synonym: "IPP-2" EXACT [UniProtKB:P41236] xref: EMBL:AAC51206.1 xref: EMBL:AAH07655.1 xref: EMBL:AAL48322.1 xref: EMBL:CAA55475.1 xref: EMBL:CAA82754.1 xref: EMBL:CAB41680.1 xref: UniProtKB:P41236 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018302 ! PPP1R2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0067128 ! IPP2_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0067129 ! IPP2_HUMAN-Phosphothreonine73 relationship: transforms_into CCO:B0067130 ! IPP2_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0067131 ! IPP2_HUMAN-Phosphothreonine89 relationship: transforms_into CCO:B0067132 ! IPP2_HUMAN-Phosphothreonine92 relationship: transforms_into CCO:B0067133 ! IPP2_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0067134 ! IPP2_HUMAN-Phosphoserine122 [Term] id: CCO:B0055340 name: TNFL9_HUMAN def: "Tumor necrosis factor ligand superfamily member 9" [UniProtKB:P41273] synonym: "4-1BB ligand" EXACT [UniProtKB:P41273] synonym: "4-1BBL" EXACT [UniProtKB:P41273] xref: EMBL:AAA53134.1 xref: EMBL:AAI04806.1 xref: EMBL:AAI04808.1 xref: UniProtKB:P41273 xref: UniProtKB:Q2M3S2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020306 ! TNFSF9_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055341 name: PACR_HUMAN def: "Pituitary adenylate cyclase-activating polypeptide type I receptor precursor" [UniProtKB:P41586] synonym: "PACAP type I receptor" EXACT [UniProtKB:P41586] synonym: "PACAP-R-1" EXACT [UniProtKB:P41586] xref: EMBL:AAA19323.1 xref: EMBL:AAQ72806.1 xref: EMBL:BAA04466.1 xref: EMBL:BAC05923.1 xref: UniProtKB:P41586 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019286 ! ADCYAP1R1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055342 name: VIPR2_HUMAN def: "Vasoactive intestinal polypeptide receptor 2 precursor" [UniProtKB:P41587] synonym: "Helodermin-preferring VIP receptor" EXACT [UniProtKB:P41587] synonym: "PACAP type III receptor" EXACT [UniProtKB:P41587] synonym: "PACAP-R-3" EXACT [UniProtKB:P41587] synonym: "Pituitary adenylate cyclase-activating polypeptide type III receptor" EXACT [UniProtKB:P41587] synonym: "VIP-R-2" EXACT [UniProtKB:P41587] xref: EMBL:AAC37569.1 xref: EMBL:AAC41756.1 xref: EMBL:AAC50872.1 xref: EMBL:AAH10569.1 xref: EMBL:CAA64474.1 xref: EMBL:CAB41899.1 xref: UniProtKB:P41587 xref: UniProtKB:Q13053 xref: UniProtKB:Q15870 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020451 ! VIPR2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055343 name: 5HT2B_HUMAN def: "5-hydroxytryptamine receptor 2B" [UniProtKB:P41595] synonym: "5-HT-2B" EXACT [UniProtKB:P41595] synonym: "Serotonin receptor 2B" EXACT [UniProtKB:P41595] xref: EMBL:AAD39259.1 xref: EMBL:AAH63123.1 xref: EMBL:AAN01277.1 xref: EMBL:AAX93128.1 xref: EMBL:CAA54513.1 xref: EMBL:CAA85319.1 xref: UniProtKB:P41595 xref: UniProtKB:Q53TI1 xref: UniProtKB:Q62221 xref: UniProtKB:Q6P523 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016855 ! HTR2B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055344 name: CCR2_HUMAN def: "C-C chemokine receptor type 2" [UniProtKB:P41597] synonym: "C-C CKR-2" EXACT [UniProtKB:P41597] synonym: "CC-CKR-2" EXACT [UniProtKB:P41597] synonym: "CCR-2" EXACT [UniProtKB:P41597] synonym: "CCR2" EXACT [UniProtKB:P41597] synonym: "CD192 antigen" EXACT [UniProtKB:P41597] synonym: "MCP-1-R" EXACT [UniProtKB:P41597] synonym: "Monocyte chemoattractant protein 1 receptor" EXACT [UniProtKB:P41597] xref: EMBL:AAA19119.1 xref: EMBL:AAA19120.1 xref: EMBL:AAB57791.1 xref: EMBL:AAB57792.1 xref: EMBL:AAC51636.1 xref: EMBL:AAC51637.1 xref: EMBL:AAH74751.1 xref: EMBL:AAI26453.1 xref: EMBL:AAN16400.1 xref: EMBL:BAA06253.1 xref: UniProtKB:A0AVQ3 xref: UniProtKB:P41597 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017277 ! CCR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: transforms_into CCO:B0064123 ! CCR2_HUMAN-Sulfotyrosine26 [Term] id: CCO:B0055345 name: ELK3_HUMAN def: "ETS domain-containing protein Elk-3" [UniProtKB:P41970] synonym: "ETS-related protein ERP" EXACT [UniProtKB:P41970] synonym: "ETS-related protein NET" EXACT [UniProtKB:P41970] synonym: "SAP-2" EXACT [UniProtKB:P41970] synonym: "SRF accessory protein 2" EXACT [UniProtKB:P41970] xref: EMBL:AAH17371.1 xref: EMBL:CAA85309.1 xref: EMBL:CAG47047.1 xref: UniProtKB:P41970 xref: UniProtKB:Q6FG57 xref: UniProtKB:Q6GU29 xref: UniProtKB:Q9UD17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017686 ! ELK3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0004989 ! purine-rich negative regulatory element binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0064981 ! ELK3_HUMAN-Phosphoserine245 [Term] id: CCO:B0055346 name: CD86_HUMAN def: "T-lymphocyte activation antigen CD86 precursor" [UniProtKB:P42081] synonym: "Activation B7-2 antigen" EXACT [UniProtKB:P42081] synonym: "B70" EXACT [UniProtKB:P42081] synonym: "BU63" EXACT [UniProtKB:P42081] synonym: "CD86 antigen" EXACT [UniProtKB:P42081] synonym: "CTLA-4 counter-receptor B7.2" EXACT [UniProtKB:P42081] synonym: "FUN-1" EXACT [UniProtKB:P42081] xref: EMBL:AAA58389.1 xref: EMBL:AAA86473.1 xref: EMBL:AAB03814.1 xref: EMBL:AAH40261.1 xref: EMBL:ABK41931.1 xref: EMBL:CAG46642.1 xref: UniProtKB:A0N0P0 xref: UniProtKB:P42081 xref: UniProtKB:Q13655 xref: UniProtKB:Q6FHB1 xref: UniProtKB:Q6GTS4 xref: UniProtKB:Q7M4L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017313 ! CD86_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017815 ! cd86-ctla4-1 direct interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002140 ! positive regulation of lymphotoxin A biosynthetic process relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002345 ! positive regulation of interleukin-4 biosynthetic process relationship: participates_in CCO:P0002444 ! positive regulation of T-helper 2 cell differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0055347 name: ASIP_HUMAN def: "Agouti-signaling protein precursor" [UniProtKB:P42127] synonym: "Agouti switch protein" EXACT [UniProtKB:P42127] synonym: "ASP" EXACT [UniProtKB:P42127] xref: EMBL:AAA89208.1 xref: EMBL:AAB61247.1 xref: EMBL:AAI04239.1 xref: EMBL:AAI04240.1 xref: EMBL:CAB96679.1 xref: UniProtKB:P42127 xref: UniProtKB:Q3SXL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017083 ! ASIP_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0055348 name: LAP2A_HUMAN def: "Lamina-associated polypeptide 2, isoform alpha" [UniProtKB:P42166] synonym: "Thymopoietin isoform alpha" EXACT [UniProtKB:P42166] synonym: "Thymopoietin-related peptide isoform alpha" EXACT [UniProtKB:P42166] synonym: "TP alpha" EXACT [UniProtKB:P42166] synonym: "TPRP isoform alpha" EXACT [UniProtKB:P42166] xref: EMBL:AAB33958.1 xref: EMBL:AAB60329.1 xref: EMBL:AAB60433.1 xref: UniProtKB:P08918 xref: UniProtKB:P08919 xref: UniProtKB:P42166 xref: UniProtKB:Q14860 xref: UniProtKB:Q16295 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018456 ! TMPO_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0019178 ! usp7-tmpo physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0067520 ! LAP2A_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0067521 ! LAP2A_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0067522 ! LAP2A_HUMAN-Phosphothreonine74 relationship: transforms_into CCO:B0067523 ! LAP2A_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0067524 ! LAP2A_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0067525 ! LAP2A_HUMAN-Phosphothreonine160 relationship: transforms_into CCO:B0067526 ! LAP2A_HUMAN-Phosphothreonine164 relationship: transforms_into CCO:B0067527 ! LAP2A_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0067528 ! LAP2A_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0067529 ! LAP2A_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0067530 ! LAP2A_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0067531 ! LAP2A_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0067532 ! LAP2A_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0067533 ! LAP2A_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0067534 ! LAP2A_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0067535 ! LAP2A_HUMAN-Phosphoserine424 [Term] id: CCO:B0055349 name: RHG25_HUMAN def: "Rho GTPase-activating protein 25" [UniProtKB:P42331] synonym: "Rho-type GTPase-activating protein 25" EXACT [UniProtKB:P42331] xref: EMBL:AAH39591.1 xref: EMBL:BAA06125.2 xref: UniProtKB:P42331 xref: UniProtKB:Q8IXQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019725 ! ARHGAP25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069983 ! RHG25_HUMAN-Phosphoserine400 [Term] id: CCO:B0055350 name: PI4KA_HUMAN def: "Phosphatidylinositol 4-kinase alpha" [UniProtKB:P42356] synonym: "EC 2.7.1.67" EXACT [UniProtKB:P42356] synonym: "PI4-kinase alpha" EXACT [UniProtKB:P42356] synonym: "PI4K-alpha" EXACT [UniProtKB:P42356] synonym: "PtdIns-4-kinase alpha" EXACT [UniProtKB:P42356] xref: EMBL:AAA56839.1 xref: EMBL:AAD13352.1 xref: EMBL:AAH18120.2 xref: EMBL:AAH53654.1 xref: UniProtKB:P42356 xref: UniProtKB:Q7Z625 xref: UniProtKB:Q9UPG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019393 ! PI4KA_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0000837 ! 1-phosphatidylinositol 4-kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000379 ! Golgi-associated vesicle relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0020466 ! strn4-pik4ca physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0069293 ! PI4KA_HUMAN-Phosphoserine198 relationship: transforms_into CCO:B0069294 ! PI4KA_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0069295 ! PI4KA_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0069296 ! PI4KA_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0069297 ! PI4KA_HUMAN-Phosphoserine207 [Term] id: CCO:B0055351 name: CASP3_HUMAN def: "Caspase-3 precursor" [UniProtKB:P42574] synonym: "Apopain" EXACT [UniProtKB:P42574] synonym: "CASP-3" EXACT [UniProtKB:P42574] synonym: "CPP-32" EXACT [UniProtKB:P42574] synonym: "Cysteine protease CPP32" EXACT [UniProtKB:P42574] synonym: "EC 3.4.22.56" EXACT [UniProtKB:P42574] synonym: "SCA-1" EXACT [UniProtKB:P42574] synonym: "SREBP cleavage activity 1" EXACT [UniProtKB:P42574] synonym: "Yama protein" EXACT [UniProtKB:P42574] xref: EMBL:AAA65015.1 xref: EMBL:AAA74929.1 xref: EMBL:AAB60355.1 xref: EMBL:AAH16926.1 xref: EMBL:AAO25654.1 xref: EMBL:CAC88866.1 xref: UniProtKB:P42574 xref: UniProtKB:Q96AN1 xref: UniProtKB:Q96KP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017236 ! CASP3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0018115 ! birc4-casp3-1 physical interaction relationship: participates_in CCO:I0018726 ! wnk3-casp3-1 physical interaction relationship: participates_in CCO:I0018789 ! birc2-casp3-3 physical interaction relationship: participates_in CCO:I0018790 ! birc7-casp3-4 physical interaction relationship: participates_in CCO:I0019335 ! wnk3-casp3-2 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0001252 ! nuclear fragmentation during apoptosis relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0064073 ! CASP3_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0064074 ! CASP3_HUMAN-S-nitrosocysteine163 [Term] id: CCO:B0055352 name: CASP2_HUMAN def: "Caspase-2 precursor" [UniProtKB:P42575] synonym: "CASP-2" EXACT [UniProtKB:P42575] synonym: "EC 3.4.22.55" EXACT [UniProtKB:P42575] synonym: "ICH-1 protease" EXACT [UniProtKB:P42575] synonym: "NEDD-2" EXACT [UniProtKB:P42575] synonym: "Neural precursor cell expressed developmentally down-regulated protein 2" EXACT [UniProtKB:P42575] xref: EMBL:AAA58959.1 xref: EMBL:AAA58960.1 xref: EMBL:AAH02427.2 xref: EMBL:AAK00300.1 xref: EMBL:AAO25653.1 xref: EMBL:AAP22346.1 xref: EMBL:AAP22347.1 xref: EMBL:AAP22349.1 xref: EMBL:AAP35904.1 xref: EMBL:BAD92877.1 xref: EMBL:CAG46548.1 xref: UniProtKB:P42575 xref: UniProtKB:P42576 xref: UniProtKB:Q59F21 xref: UniProtKB:Q7KZL6 xref: UniProtKB:Q86UJ3 xref: UniProtKB:Q9BUP7 xref: UniProtKB:Q9BZK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017235 ! CASP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0016258 ! casp2-cradd-4 physical interaction relationship: participates_in CCO:I0017776 ! casp2-raidd-pidd physical interaction relationship: participates_in CCO:I0017777 ! casp2-raidd-pidd-1 physical interaction relationship: participates_in CCO:I0017778 ! casp2-raidd-pidd-2 physical interaction relationship: participates_in CCO:I0018021 ! casp2-cradd-1 physical interaction relationship: participates_in CCO:I0018023 ! casp2-cradd-3 physical interaction relationship: participates_in CCO:I0018024 ! casp2-cradd-5 physical interaction relationship: participates_in CCO:I0018105 ! casp2-pidd-3 colocalization relationship: participates_in CCO:I0018617 ! casp2-cradd-6 physical interaction relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0055353 name: TEC_HUMAN def: "Tyrosine-protein kinase Tec" [UniProtKB:P42680] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P42680] xref: EMBL:AAI01712.1 xref: EMBL:AAI01714.1 xref: EMBL:BAA06171.1 xref: UniProtKB:P42680 xref: UniProtKB:Q3MIS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020227 ! TEC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0071322 ! TEC_HUMAN-Phosphotyrosine206 relationship: transforms_into CCO:B0071323 ! TEC_HUMAN-Phosphotyrosine519 [Term] id: CCO:B0055354 name: I12R1_HUMAN def: "Interleukin-12 receptor beta-1 chain precursor" [UniProtKB:P42701] synonym: "CD212 antigen" EXACT [UniProtKB:P42701] synonym: "IL-12 receptor beta component" EXACT [UniProtKB:P42701] synonym: "IL-12R-beta1" EXACT [UniProtKB:P42701] synonym: "IL-12RB1" EXACT [UniProtKB:P42701] synonym: "Interleukin-12 receptor beta" EXACT [UniProtKB:P42701] xref: EMBL:AAA21340.1 xref: EMBL:AAV28734.1 xref: EMBL:CAC10446.1 xref: UniProtKB:P42701 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018196 ! IL12RB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001254 ! interleukin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055355 name: LIFR_HUMAN def: "Leukemia inhibitory factor receptor precursor" [UniProtKB:P42702] synonym: "CD118 antigen" EXACT [UniProtKB:P42702] synonym: "LIF receptor" EXACT [UniProtKB:P42702] synonym: "LIF-R" EXACT [UniProtKB:P42702] xref: EMBL:AAB61897.1 xref: EMBL:CAA43805.1 xref: UniProtKB:P42702 xref: UniProtKB:Q6LCD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018492 ! LIFR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001268 ! leukemia inhibitory factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: transforms_into CCO:B0067645 ! LIFR_HUMAN-Phosphoserine927 [Term] id: CCO:B0055356 name: NSG1_HUMAN def: "Neuron-specific protein family member 1" [UniProtKB:P42857] synonym: "Brain neuron cytoplasmic protein 1" EXACT [UniProtKB:P42857] xref: EMBL:AAA60152.1 xref: EMBL:AAA60355.1 xref: EMBL:AAH01745.1 xref: EMBL:AAH34227.1 xref: UniProtKB:P42857 xref: UniProtKB:Q49AQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018876 ! NSG1_human relationship: has_function CCO:F0008009 ! dopamine receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway [Term] id: CCO:B0055357 name: GUC1A_HUMAN def: "Guanylyl cyclase-activating protein 1" [UniProtKB:P43080] synonym: "GCAP 1" EXACT [UniProtKB:P43080] synonym: "Guanylate cyclase activator 1A" EXACT [UniProtKB:P43080] xref: EMBL:AAA60541.1 xref: EMBL:AAA60542.1 xref: EMBL:AAH31663.1 xref: EMBL:CAB89167.1 xref: EMBL:CAD92530.1 xref: UniProtKB:P43080 xref: UniProtKB:Q7Z6T1 xref: UniProtKB:Q9NU14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018091 ! GUCA1A_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001692 ! calcium sensitive guanylate cyclase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055358 name: PF2R_HUMAN def: "Prostaglandin F2-alpha receptor" [UniProtKB:P43088] synonym: "PGF receptor" EXACT [UniProtKB:P43088] synonym: "PGF2 alpha receptor" EXACT [UniProtKB:P43088] synonym: "Prostanoid FP receptor" EXACT [UniProtKB:P43088] xref: EMBL:AAA17684.1 xref: EMBL:AAB63152.1 xref: EMBL:AAI12966.1 xref: EMBL:AAQ76788.1 xref: EMBL:BAA94756.1 xref: EMBL:CAC36038.1 xref: UniProtKB:P43088 xref: UniProtKB:Q2KHP3 xref: UniProtKB:Q9P1X4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019373 ! PTGFR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001300 ! prostaglandin F receptor activity relationship: has_function CCO:F0001301 ! thromboxane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055359 name: PE2R2_HUMAN def: "Prostaglandin E2 receptor EP2 subtype" [UniProtKB:P43116] synonym: "PGE receptor, EP2 subtype" EXACT [UniProtKB:P43116] synonym: "Prostanoid EP2 receptor" EXACT [UniProtKB:P43116] xref: EMBL:AAA61681.1 xref: EMBL:AAD44177.1 xref: EMBL:AAH93927.1 xref: EMBL:AAH93929.1 xref: EMBL:AAP32303.1 xref: EMBL:ABD48958.1 xref: EMBL:CAA58749.1 xref: UniProtKB:P43116 xref: UniProtKB:Q52LG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019356 ! PTGER2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_function CCO:F0001301 ! thromboxane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055360 name: PI2R_HUMAN def: "Prostacyclin receptor" [UniProtKB:P43119] synonym: "PGI receptor" EXACT [UniProtKB:P43119] synonym: "Prostaglandin I2 receptor" EXACT [UniProtKB:P43119] synonym: "Prostanoid IP receptor" EXACT [UniProtKB:P43119] xref: EMBL:AAA36448.1 xref: EMBL:AAH75814.1 xref: EMBL:AAO92301.1 xref: EMBL:BAA05008.1 xref: EMBL:BAA06110.1 xref: EMBL:BAA07325.1 xref: UniProtKB:P43119 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019391 ! PTGIR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: transforms_into CCO:B0069291 ! PI2R_HUMAN-Cysteine methyl ester383 [Term] id: CCO:B0055361 name: GRK6_HUMAN def: "G protein-coupled receptor kinase 6" [UniProtKB:P43250] synonym: "EC 2.7.11.16" EXACT [UniProtKB:P43250] synonym: "G protein-coupled receptor kinase GRK6" EXACT [UniProtKB:P43250] xref: EMBL:AAA03565.1 xref: EMBL:AAA60175.1 xref: EMBL:AAC09273.1 xref: EMBL:AAC09274.1 xref: EMBL:AAH09277.1 xref: UniProtKB:O60541 xref: UniProtKB:P43250 xref: UniProtKB:Q13652 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018073 ! GRK6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066621 ! GRK6_HUMAN-Phosphoserine484 relationship: transforms_into CCO:B0066622 ! GRK6_HUMAN-Phosphothreonine485 [Term] id: CCO:B0055362 name: ETV4_HUMAN def: "ETS translocation variant 4" [UniProtKB:P43268] synonym: "Adenovirus E1A enhancer-binding protein" EXACT [UniProtKB:P43268] synonym: "E1A-F" EXACT [UniProtKB:P43268] xref: EMBL:AAA95991.1 xref: EMBL:AAD09186.1 xref: EMBL:AAH16623.1 xref: EMBL:BAA02234.1 xref: UniProtKB:P43268 xref: UniProtKB:Q96AW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017740 ! ETV4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0065169 ! ETV4_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0065170 ! ETV4_HUMAN-Phosphoserine149 [Term] id: CCO:B0055363 name: NR4A2_HUMAN def: "Nuclear receptor subfamily 4 group A member 2" [UniProtKB:P43354] synonym: "Immediate-early response protein NOT" EXACT [UniProtKB:P43354] synonym: "Orphan nuclear receptor NURR1" EXACT [UniProtKB:P43354] synonym: "Transcriptionally-inducible nuclear receptor" EXACT [UniProtKB:P43354] xref: EMBL:AAB33999.1 xref: EMBL:AAH09288.1 xref: EMBL:BAA75666.1 xref: EMBL:BAA77328.1 xref: EMBL:CAA53518.1 xref: UniProtKB:P43354 xref: UniProtKB:Q16311 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018861 ! NR4A2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002032 ! regulation of dopamine metabolic process relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068824 ! NR4A2_HUMAN-Phosphoserine181 [Term] id: CCO:B0055364 name: ZAP70_HUMAN def: "Tyrosine-protein kinase ZAP-70" [UniProtKB:P43403] synonym: "70 kDa zeta-associated protein" EXACT [UniProtKB:P43403] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P43403] synonym: "Syk-related tyrosine kinase" EXACT [UniProtKB:P43403] xref: EMBL:AAH39039.1 xref: EMBL:AAH53878.1 xref: EMBL:AAX93187.1 xref: EMBL:BAC43747.1 xref: UniProtKB:A6NFP4 xref: UniProtKB:P43403 xref: UniProtKB:Q6PIA4 xref: UniProtKB:Q8IXD6 xref: UniProtKB:Q9UBS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020542 ! ZAP70_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002396 ! positive regulation of T cell differentiation relationship: transforms_into CCO:B0071947 ! ZAP70_HUMAN-Phosphotyrosine248 relationship: transforms_into CCO:B0071948 ! ZAP70_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0071949 ! ZAP70_HUMAN-Phosphotyrosine292 relationship: transforms_into CCO:B0071950 ! ZAP70_HUMAN-Phosphotyrosine315 relationship: transforms_into CCO:B0071951 ! ZAP70_HUMAN-Phosphotyrosine319 relationship: transforms_into CCO:B0071952 ! ZAP70_HUMAN-Phosphotyrosine492 relationship: transforms_into CCO:B0071953 ! ZAP70_HUMAN-Phosphotyrosine493 [Term] id: CCO:B0055365 name: KSYK_HUMAN def: "Tyrosine-protein kinase SYK" [UniProtKB:P43405] synonym: "EC 2.7.10.2" EXACT [UniProtKB:P43405] synonym: "Spleen tyrosine kinase" EXACT [UniProtKB:P43405] xref: EMBL:AAA36526.1 xref: EMBL:AAH01645.1 xref: EMBL:AAH02962.1 xref: EMBL:AAH11399.1 xref: EMBL:CAA51970.1 xref: EMBL:CAA82737.1 xref: UniProtKB:P43405 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018449 ! SYK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016109 ! syk-fcer1g-1 physical interaction relationship: participates_in CCO:I0016217 ! itgb2-syk physical interaction relationship: participates_in CCO:I0017641 ! cd22-lyn-1 physical interaction relationship: participates_in CCO:I0017719 ! syk-pou2af1 colocalization relationship: participates_in CCO:I0017898 ! ptpn6-cd22-1 physical interaction relationship: participates_in CCO:I0017904 ! ptpn-6-cd22-2 physical interaction relationship: participates_in CCO:I0017905 ! cd22-ksyk-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002182 ! positive regulation of mast cell degranulation relationship: participates_in CCO:P0002342 ! positive regulation of interleukin-3 biosynthetic process relationship: participates_in CCO:P0002366 ! positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process relationship: participates_in CCO:P0002393 ! positive regulation of B cell differentiation relationship: participates_in CCO:P0002402 ! positive regulation of gamma-delta T cell differentiation relationship: participates_in CCO:P0002713 ! positive regulation of alpha-beta T cell differentiation relationship: participates_in CCO:P0002716 ! positive regulation of alpha-beta T cell proliferation relationship: participates_in CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway relationship: transforms_into CCO:B0067501 ! KSYK_HUMAN-Phosphotyrosine296 relationship: transforms_into CCO:B0067502 ! KSYK_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0067503 ! KSYK_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0067504 ! KSYK_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0067505 ! KSYK_HUMAN-Phosphotyrosine323 relationship: transforms_into CCO:B0067506 ! KSYK_HUMAN-Phosphotyrosine348 relationship: transforms_into CCO:B0067507 ! KSYK_HUMAN-Phosphotyrosine352 relationship: transforms_into CCO:B0067508 ! KSYK_HUMAN-Phosphotyrosine525 relationship: transforms_into CCO:B0067509 ! KSYK_HUMAN-Phosphotyrosine526 relationship: transforms_into CCO:B0067510 ! KSYK_HUMAN-Phosphotyrosine546 relationship: transforms_into CCO:B0067511 ! KSYK_HUMAN-Phosphotyrosine629 relationship: transforms_into CCO:B0067512 ! KSYK_HUMAN-Phosphotyrosine630 [Term] id: CCO:B0055366 name: NAMPT_HUMAN def: "Nicotinamide phosphoribosyltransferase" [UniProtKB:P43490] synonym: "EC 2.4.2.12" EXACT [UniProtKB:P43490] synonym: "NAmPRTase" EXACT [UniProtKB:P43490] synonym: "Nampt" EXACT [UniProtKB:P43490] synonym: "Pre-B cell-enhancing factor" EXACT [UniProtKB:P43490] synonym: "Pre-B-cell colony-enhancing factor 1" EXACT [UniProtKB:P43490] synonym: "Visfatin" EXACT [UniProtKB:P43490] xref: EMBL:AAA17884.1 xref: EMBL:AAF19249.1 xref: EMBL:AAH20691.1 xref: EMBL:AAH72439.1 xref: EMBL:AAI06047.1 xref: EMBL:AAQ96862.1 xref: UniProtKB:P43490 xref: UniProtKB:Q3KQV0 xref: UniProtKB:Q8WW95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018713 ! NAMPT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0068438 ! NAMPT_HUMAN-Phosphotyrosine34 relationship: transforms_into CCO:B0068439 ! NAMPT_HUMAN-Phosphotyrosine188 [Term] id: CCO:B0055367 name: P2RY5_HUMAN def: "Oleoyl-L-alpha-lysophosphatidic acid receptor" [UniProtKB:P43657] synonym: "P2Y purinoceptor 5" EXACT [UniProtKB:P43657] synonym: "P2Y5" EXACT [UniProtKB:P43657] synonym: "Purinergic receptor 5" EXACT [UniProtKB:P43657] synonym: "RB intron encoded G-protein coupled receptor" EXACT [UniProtKB:P43657] xref: EMBL:AAB62190.1 xref: EMBL:AAH40850.1 xref: EMBL:AAH45651.1 xref: EMBL:AAH70295.1 xref: EMBL:AAI06757.1 xref: EMBL:AAL40065.1 xref: EMBL:AAN64134.1 xref: EMBL:BAD97109.1 xref: EMBL:CAD97634.1 xref: EMBL:CAD97680.1 xref: EMBL:CAD97687.1 xref: EMBL:CAH72247.1 xref: EMBL:EAX08796.1 xref: UniProtKB:A4FTW9 xref: UniProtKB:O15133 xref: UniProtKB:P43657 xref: UniProtKB:Q3KPF5 xref: UniProtKB:Q53FA0 xref: UniProtKB:Q5VW44 xref: UniProtKB:Q7Z3S0 xref: UniProtKB:Q7Z3S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019268 ! P2RY5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055368 name: ACHA4_HUMAN def: "Neuronal acetylcholine receptor subunit alpha-4 precursor" [UniProtKB:P43681] xref: EMBL:AAA64743.1 xref: EMBL:AAB40111.1 xref: EMBL:AAH96290.1 xref: EMBL:AAY88737.1 xref: EMBL:CAA60959.1 xref: EMBL:CAA61893.1 xref: EMBL:CAA69698.1 xref: UniProtKB:P43681 xref: UniProtKB:Q4JGR7 xref: UniProtKB:Q4VAQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016889 ! CHRNA4_human relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0005634 ! acetylcholine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001078 ! regulation of dopamine secretion [Term] id: CCO:B0055369 name: GATA4_HUMAN def: "Transcription factor GATA-4" [UniProtKB:P43694] synonym: "GATA-binding factor 4" EXACT [UniProtKB:P43694] xref: EMBL:AAA58496.1 xref: EMBL:AAI01581.1 xref: EMBL:AAI05109.1 xref: UniProtKB:P43694 xref: UniProtKB:Q3MJ45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017872 ! GATA4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0055370 name: NKX21_HUMAN def: "Homeobox protein Nkx-2.1" [UniProtKB:P43699] synonym: "Homeobox protein NK-2 homolog A" EXACT [UniProtKB:P43699] synonym: "Thyroid nuclear factor 1" EXACT [UniProtKB:P43699] synonym: "Thyroid transcription factor 1" EXACT [UniProtKB:P43699] synonym: "TTF-1" EXACT [UniProtKB:P43699] xref: EMBL:AAA86099.1 xref: EMBL:AAA89066.1 xref: EMBL:AAB52381.1 xref: EMBL:AAC50125.1 xref: EMBL:AAH06221.2 xref: EMBL:BAA23527.1 xref: EMBL:BAA23529.1 xref: EMBL:CAA58053.1 xref: UniProtKB:O14954 xref: UniProtKB:O14955 xref: UniProtKB:P43699 xref: UniProtKB:Q9BRJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018794 ! NKX2-1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055371 name: ABCG1_HUMAN def: "ATP-binding cassette sub-family G member 1" [UniProtKB:P45844] synonym: "ATP-binding cassette transporter 8" EXACT [UniProtKB:P45844] synonym: "White protein homolog" EXACT [UniProtKB:P45844] xref: EMBL:AAC51098.1 xref: EMBL:AAH29158.2 xref: EMBL:AAK28833.1 xref: EMBL:AAK28834.1 xref: EMBL:AAK28835.1 xref: EMBL:AAK28836.1 xref: EMBL:AAK28837.1 xref: EMBL:AAK28838.1 xref: EMBL:AAK28839.1 xref: EMBL:AAK28840.1 xref: EMBL:AAK28841.1 xref: EMBL:AAK28842.1 xref: EMBL:AAL06598.1 xref: EMBL:BAA95530.1 xref: EMBL:BAB13728.2 xref: EMBL:CAA62631.1 xref: EMBL:CAC00730.1 xref: UniProtKB:P45844 xref: UniProtKB:Q86SU8 xref: UniProtKB:Q96L76 xref: UniProtKB:Q9BXK6 xref: UniProtKB:Q9BXK7 xref: UniProtKB:Q9BXK8 xref: UniProtKB:Q9BXK9 xref: UniProtKB:Q9BXL0 xref: UniProtKB:Q9BXL1 xref: UniProtKB:Q9BXL2 xref: UniProtKB:Q9BXL3 xref: UniProtKB:Q9BXL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016873 ! ABCG1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001671 ! phospholipid transporter activity relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0003584 ! cholesterol transporter activity relationship: has_function CCO:F0004142 ! toxin transporter activity relationship: has_function CCO:F0005504 ! sterol-transporting ATPase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005867 ! ADP binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002387 ! positive regulation of cholesterol biosynthetic process [Term] id: CCO:B0055372 name: GPR3_HUMAN def: "Probable G-protein coupled receptor 3" [UniProtKB:P46089] synonym: "ACCA orphan receptor" EXACT [UniProtKB:P46089] xref: EMBL:AAA64594.1 xref: EMBL:AAA73560.1 xref: EMBL:AAB60402.1 xref: EMBL:AAH32702.1 xref: EMBL:CAA58787.1 xref: EMBL:CAC18517.1 xref: UniProtKB:P46089 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018020 ! GPR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: transforms_into CCO:B0066546 ! GPR3_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0066547 ! GPR3_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0066548 ! GPR3_HUMAN-Phosphoserine328 [Term] id: CCO:B0055373 name: GPR1_HUMAN def: "Probable G-protein coupled receptor 1" [UniProtKB:P46091] xref: EMBL:AAA64592.1 xref: EMBL:AAH58005.1 xref: EMBL:AAH67833.1 xref: EMBL:AAY15063.1 xref: UniProtKB:P46091 xref: UniProtKB:Q53TR9 xref: UniProtKB:Q6NVX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018007 ! GPR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055374 name: XCR1_HUMAN def: "Chemokine XC receptor 1" [UniProtKB:P46094] synonym: "G-protein coupled receptor 5" EXACT [UniProtKB:P46094] synonym: "Lymphotactin receptor" EXACT [UniProtKB:P46094] synonym: "XC chemokine receptor 1" EXACT [UniProtKB:P46094] xref: EMBL:AAA62837.1 xref: EMBL:AAH69075.1 xref: EMBL:AAH69589.1 xref: EMBL:AAP32301.1 xref: UniProtKB:P46094 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020508 ! XCR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055375 name: GPR6_HUMAN def: "Sphingosine 1-phosphate receptor GPR6" [UniProtKB:P46095] synonym: "G-protein coupled receptor 6" EXACT [UniProtKB:P46095] xref: EMBL:AAA63181.1 xref: EMBL:AAA91631.1 xref: EMBL:AAH43414.1 xref: EMBL:AAI17299.1 xref: EMBL:AAI26302.1 xref: EMBL:CAI17125.1 xref: UniProtKB:P46095 xref: UniProtKB:Q17RJ7 xref: UniProtKB:Q5SYL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018030 ! GPR6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066549 ! GPR6_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0066550 ! GPR6_HUMAN-Phosphoserine358 relationship: transforms_into CCO:B0066551 ! GPR6_HUMAN-Phosphoserine360 [Term] id: CCO:B0055376 name: CRK_HUMAN def: "Proto-oncogene C-crk" [UniProtKB:P46108] synonym: "Adapter molecule crk" EXACT [UniProtKB:P46108] synonym: "p38" EXACT [UniProtKB:P46108] xref: EMBL:AAB28213.1 xref: EMBL:AAH01718.1 xref: EMBL:AAH08506.1 xref: EMBL:AAP35941.1 xref: EMBL:BAA01505.1 xref: UniProtKB:P46108 xref: UniProtKB:Q96HJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017460 ! CRK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015913 ! map4k5-crk-2 physical interaction relationship: participates_in CCO:I0015916 ! map4k5-crk-4 physical interaction relationship: participates_in CCO:I0016010 ! map4k5-crk-1 physical interaction relationship: participates_in CCO:I0016141 ! map4k1-crk-2 physical interaction relationship: participates_in CCO:I0016163 ! atxn1-crk physical interaction relationship: participates_in CCO:I0016246 ! map4k5-crk-3 physical interaction relationship: participates_in CCO:I0017555 ! crk-atxn1 physical interaction relationship: participates_in CCO:I0018754 ! abl2-crk-2 phosphorylation relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064473 ! CRK_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0064474 ! CRK_HUMAN-Phosphothreonine42 relationship: transforms_into CCO:B0064475 ! CRK_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0064476 ! CRK_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0064477 ! CRK_HUMAN-Phosphotyrosine221 relationship: transforms_into CCO:B0064478 ! CRK_HUMAN-Phosphotyrosine239 [Term] id: CCO:B0055377 name: CRKL_HUMAN def: "Crk-like protein" [UniProtKB:P46109] xref: EMBL:AAH43500.1 xref: EMBL:CAA42199.1 xref: EMBL:CAG30309.1 xref: UniProtKB:P46109 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017459 ! CRKL_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015914 ! map4k1-crkl-2 physical interaction relationship: participates_in CCO:I0015915 ! map4k1-crkl-3 physical interaction relationship: participates_in CCO:I0015917 ! map4k1-crkl-6 physical interaction relationship: participates_in CCO:I0016011 ! map4k5-crkl-1 physical interaction relationship: participates_in CCO:I0016150 ! map4k1-crkl-4 physical interaction relationship: participates_in CCO:I0016247 ! map4k1-crkl-5 physical interaction relationship: participates_in CCO:I0018605 ! insr-crkl-1 physical interaction relationship: participates_in CCO:I0018608 ! insr-crkl-2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0064469 ! CRKL_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0064470 ! CRKL_HUMAN-Phosphotyrosine132 relationship: transforms_into CCO:B0064471 ! CRKL_HUMAN-Phosphotyrosine207 relationship: transforms_into CCO:B0064472 ! CRKL_HUMAN-Phosphotyrosine251 [Term] id: CCO:B0055378 name: BKRB1_HUMAN def: "B1 bradykinin receptor" [UniProtKB:P46663] synonym: "B1R" EXACT [UniProtKB:P46663] synonym: "BK-1 receptor" EXACT [UniProtKB:P46663] xref: EMBL:AAA21346.1 xref: EMBL:AAB60693.1 xref: EMBL:AAC50594.1 xref: EMBL:AAH34705.1 xref: EMBL:AAP32296.1 xref: EMBL:BAC06112.1 xref: EMBL:CAB45650.1 xref: UniProtKB:P46663 xref: UniProtKB:Q546S7 xref: UniProtKB:Q8N0Y8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017162 ! BDKRB1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001289 ! bradykinin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055379 name: IEX1_HUMAN def: "Radiation-inducible immediate-early gene IEX-1" [UniProtKB:P46695] synonym: "Differentiation-dependent gene 2 protein" EXACT [UniProtKB:P46695] synonym: "Immediate early protein GLY96" EXACT [UniProtKB:P46695] synonym: "Immediate early response 3 protein" EXACT [UniProtKB:P46695] synonym: "PACAP-responsive gene 1 protein" EXACT [UniProtKB:P46695] synonym: "Protein DIF-2" EXACT [UniProtKB:P46695] synonym: "Protein PRG1" EXACT [UniProtKB:P46695] xref: EMBL:AAB36278.1 xref: EMBL:AAH00844.1 xref: EMBL:AAH05080.1 xref: EMBL:AAP35349.1 xref: EMBL:BAB63319.1 xref: EMBL:CAA65304.1 xref: EMBL:CAA74886.1 xref: UniProtKB:P46695 xref: UniProtKB:Q92691 xref: UniProtKB:Q93044 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018218 ! IER3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0055380 name: MAP1B_HUMAN def: "Microtubule-associated protein 1B" [UniProtKB:P46821] synonym: "MAP-1B" EXACT [UniProtKB:P46821] xref: EMBL:AAA18904.1 xref: UniProtKB:P46821 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018566 ! MAP1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016135 ! gan-map1b physical interaction relationship: participates_in CCO:I0017764 ! gan-map1b-1 physical interaction relationship: participates_in CCO:I0019282 ! gan-map1b-2 physical interaction relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: transforms_into CCO:B0067859 ! MAP1B_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0067860 ! MAP1B_HUMAN-Phosphothreonine527 relationship: transforms_into CCO:B0067861 ! MAP1B_HUMAN-Phosphoserine541 relationship: transforms_into CCO:B0067862 ! MAP1B_HUMAN-Phosphoserine544 relationship: transforms_into CCO:B0067863 ! MAP1B_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0067864 ! MAP1B_HUMAN-Phosphothreonine569 relationship: transforms_into CCO:B0067865 ! MAP1B_HUMAN-Phosphoserine614 relationship: transforms_into CCO:B0067866 ! MAP1B_HUMAN-Phosphoserine828 relationship: transforms_into CCO:B0067867 ! MAP1B_HUMAN-Phosphoserine831 relationship: transforms_into CCO:B0067868 ! MAP1B_HUMAN-Phosphoserine832 relationship: transforms_into CCO:B0067869 ! MAP1B_HUMAN-Phosphoserine937 relationship: transforms_into CCO:B0067870 ! MAP1B_HUMAN-Phosphoserine992 relationship: transforms_into CCO:B0067871 ! MAP1B_HUMAN-Phosphoserine995 relationship: transforms_into CCO:B0067872 ! MAP1B_HUMAN-Phosphoserine1016 relationship: transforms_into CCO:B0067873 ! MAP1B_HUMAN-Phosphotyrosine1062 relationship: transforms_into CCO:B0067874 ! MAP1B_HUMAN-Phosphothreonine1067 relationship: transforms_into CCO:B0067875 ! MAP1B_HUMAN-Phosphoserine1154 relationship: transforms_into CCO:B0067876 ! MAP1B_HUMAN-Phosphoserine1208 relationship: transforms_into CCO:B0067877 ! MAP1B_HUMAN-Phosphoserine1252 relationship: transforms_into CCO:B0067878 ! MAP1B_HUMAN-Phosphoserine1256 relationship: transforms_into CCO:B0067879 ! MAP1B_HUMAN-Phosphoserine1260 relationship: transforms_into CCO:B0067880 ! MAP1B_HUMAN-Phosphoserine1265 relationship: transforms_into CCO:B0067881 ! MAP1B_HUMAN-Phosphoserine1276 relationship: transforms_into CCO:B0067882 ! MAP1B_HUMAN-Phosphoserine1280 relationship: transforms_into CCO:B0067883 ! MAP1B_HUMAN-Phosphothreonine1282 relationship: transforms_into CCO:B0067884 ! MAP1B_HUMAN-Phosphoserine1312 relationship: transforms_into CCO:B0067885 ! MAP1B_HUMAN-Phosphoserine1322 relationship: transforms_into CCO:B0067886 ! MAP1B_HUMAN-Phosphoserine1324 relationship: transforms_into CCO:B0067887 ! MAP1B_HUMAN-Phosphotyrosine1336 relationship: transforms_into CCO:B0067888 ! MAP1B_HUMAN-Phosphotyrosine1337 relationship: transforms_into CCO:B0067889 ! MAP1B_HUMAN-Phosphoserine1339 relationship: transforms_into CCO:B0067890 ! MAP1B_HUMAN-Phosphoserine1376 relationship: transforms_into CCO:B0067891 ! MAP1B_HUMAN-Phosphoserine1378 relationship: transforms_into CCO:B0067892 ! MAP1B_HUMAN-Phosphoserine1387 relationship: transforms_into CCO:B0067893 ! MAP1B_HUMAN-Phosphoserine1389 relationship: transforms_into CCO:B0067894 ! MAP1B_HUMAN-Phosphoserine1396 relationship: transforms_into CCO:B0067895 ! MAP1B_HUMAN-Phosphoserine1400 relationship: transforms_into CCO:B0067896 ! MAP1B_HUMAN-Phosphoserine1408 relationship: transforms_into CCO:B0067897 ! MAP1B_HUMAN-Phosphoserine1427 relationship: transforms_into CCO:B0067898 ! MAP1B_HUMAN-Phosphoserine1438 relationship: transforms_into CCO:B0067899 ! MAP1B_HUMAN-Phosphoserine1443 relationship: transforms_into CCO:B0067900 ! MAP1B_HUMAN-Phosphoserine1501 relationship: transforms_into CCO:B0067901 ! MAP1B_HUMAN-Phosphoserine1618 relationship: transforms_into CCO:B0067902 ! MAP1B_HUMAN-Phosphoserine1620 relationship: transforms_into CCO:B0067903 ! MAP1B_HUMAN-Phosphoserine1625 relationship: transforms_into CCO:B0067904 ! MAP1B_HUMAN-Phosphothreonine1633 relationship: transforms_into CCO:B0067905 ! MAP1B_HUMAN-Phosphotyrosine1762 relationship: transforms_into CCO:B0067906 ! MAP1B_HUMAN-Phosphoserine1772 relationship: transforms_into CCO:B0067907 ! MAP1B_HUMAN-Phosphoserine1779 relationship: transforms_into CCO:B0067908 ! MAP1B_HUMAN-Phosphoserine1782 relationship: transforms_into CCO:B0067909 ! MAP1B_HUMAN-Phosphoserine1785 relationship: transforms_into CCO:B0067910 ! MAP1B_HUMAN-Phosphothreonine1788 relationship: transforms_into CCO:B0067911 ! MAP1B_HUMAN-Phosphoserine1793 relationship: transforms_into CCO:B0067912 ! MAP1B_HUMAN-Phosphotyrosine1796 relationship: transforms_into CCO:B0067913 ! MAP1B_HUMAN-Phosphoserine1797 relationship: transforms_into CCO:B0067914 ! MAP1B_HUMAN-Phosphoserine1817 relationship: transforms_into CCO:B0067915 ! MAP1B_HUMAN-Phosphoserine1819 relationship: transforms_into CCO:B0067916 ! MAP1B_HUMAN-Phosphotyrosine1830 relationship: transforms_into CCO:B0067917 ! MAP1B_HUMAN-Phosphotyrosine1870 relationship: transforms_into CCO:B0067918 ! MAP1B_HUMAN-Phosphotyrosine1872 relationship: transforms_into CCO:B0067919 ! MAP1B_HUMAN-Phosphoserine1881 relationship: transforms_into CCO:B0067920 ! MAP1B_HUMAN-Phosphotyrosine1904 relationship: transforms_into CCO:B0067921 ! MAP1B_HUMAN-Phosphotyrosine1905 relationship: transforms_into CCO:B0067922 ! MAP1B_HUMAN-Phosphoserine1915 relationship: transforms_into CCO:B0067923 ! MAP1B_HUMAN-Phosphothreonine1932 relationship: transforms_into CCO:B0067924 ! MAP1B_HUMAN-Phosphotyrosine1938 relationship: transforms_into CCO:B0067925 ! MAP1B_HUMAN-Phosphotyrosine1940 relationship: transforms_into CCO:B0067926 ! MAP1B_HUMAN-Phosphothreonine1949 relationship: transforms_into CCO:B0067927 ! MAP1B_HUMAN-Phosphotyrosine1957 relationship: transforms_into CCO:B0067928 ! MAP1B_HUMAN-Phosphotyrosine1974 relationship: transforms_into CCO:B0067929 ! MAP1B_HUMAN-Phosphotyrosine2025 relationship: transforms_into CCO:B0067930 ! MAP1B_HUMAN-Phosphothreonine2034 relationship: transforms_into CCO:B0067931 ! MAP1B_HUMAN-Phosphoserine2072 relationship: transforms_into CCO:B0067932 ! MAP1B_HUMAN-Phosphoserine2098 relationship: transforms_into CCO:B0067933 ! MAP1B_HUMAN-Phosphoserine2209 relationship: transforms_into CCO:B0067934 ! MAP1B_HUMAN-Phosphoserine2211 relationship: transforms_into CCO:B0067935 ! MAP1B_HUMAN-Phosphoserine2289 relationship: transforms_into CCO:B0067936 ! MAP1B_HUMAN-Phosphothreonine2334 [Term] id: CCO:B0055381 name: YAP1_HUMAN def: "65 kDa Yes-associated protein" [UniProtKB:P46937] synonym: "YAP65" EXACT [UniProtKB:P46937] xref: EMBL:CAA56672.1 xref: UniProtKB:P46937 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020512 ! YAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0071903 ! YAP1_HUMAN-Phosphoserine61 relationship: transforms_into CCO:B0071904 ! YAP1_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0071905 ! YAP1_HUMAN-Phosphothreonine110 relationship: transforms_into CCO:B0071906 ! YAP1_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0071907 ! YAP1_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0071908 ! YAP1_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0071909 ! YAP1_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0071910 ! YAP1_HUMAN-Phosphothreonine143 relationship: transforms_into CCO:B0071911 ! YAP1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0071912 ! YAP1_HUMAN-Phosphothreonine154 relationship: transforms_into CCO:B0071913 ! YAP1_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0071914 ! YAP1_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0071915 ! YAP1_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0071916 ! YAP1_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0071917 ! YAP1_HUMAN-Phosphoserine321 [Term] id: CCO:B0055382 name: GALR1_HUMAN def: "Galanin receptor type 1" [UniProtKB:P47211] synonym: "GAL1-R" EXACT [UniProtKB:P47211] synonym: "GALR1" EXACT [UniProtKB:P47211] xref: EMBL:AAA50767.1 xref: EMBL:AAB60356.1 xref: EMBL:AAC51936.1 xref: EMBL:AAC95397.1 xref: EMBL:AAS47032.1 xref: UniProtKB:P47211 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017861 ! GALR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001307 ! galanin receptor activity relationship: has_function CCO:F0005746 ! neuropeptide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0055383 name: MSS4_HUMAN def: "Guanine nucleotide exchange factor MSS4" [UniProtKB:P47224] synonym: "Rab-interacting factor" EXACT [UniProtKB:P47224] xref: EMBL:AAB18264.1 xref: EMBL:AAB34955.1 xref: EMBL:AAH18488.1 xref: EMBL:AAH37392.1 xref: EMBL:AAP35797.1 xref: UniProtKB:P47224 xref: UniProtKB:Q92992 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018665 ! RABIF_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019808 ! rabif-utp14a physical interaction relationship: participates_in CCO:I0020430 ! rabif-hbxip physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055384 name: RPGP1_HUMAN def: "Rap1 GTPase-activating protein 1" [UniProtKB:P47736] synonym: "Rap1GAP" EXACT [UniProtKB:P47736] synonym: "Rap1GAP1" EXACT [UniProtKB:P47736] xref: EMBL:AAA60252.1 xref: EMBL:BAA32319.3 xref: EMBL:CAI16250.1 xref: EMBL:EAW94980.1 xref: UniProtKB:O75062 xref: UniProtKB:P47736 xref: UniProtKB:Q5T3T4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020431 ! rap1ga1-pfn2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0055385 name: GPR12_HUMAN def: "Probable G-protein coupled receptor 12" [UniProtKB:P47775] xref: EMBL:AAA91630.1 xref: EMBL:AAH67448.1 xref: EMBL:AAH67452.1 xref: EMBL:AAI12145.1 xref: EMBL:AAI12147.1 xref: EMBL:CAI14692.1 xref: UniProtKB:P47775 xref: UniProtKB:Q5T8P3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018002 ! GPR12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066543 ! GPR12_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0066544 ! GPR12_HUMAN-Phosphoserine332 [Term] id: CCO:B0055386 name: RGR_HUMAN def: "RPE-retinal G protein-coupled receptor" [UniProtKB:P47804] xref: EMBL:AAA56748.1 xref: EMBL:AAB92384.1 xref: EMBL:AAH11349.1 xref: UniProtKB:P47804 xref: UniProtKB:Q96FC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019701 ! RGR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015208 ! kiaa1279-rgr physical interaction relationship: participates_in CCO:I0019410 ! rgr-kiaa1279 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055387 name: OMP_HUMAN def: "Olfactory marker protein" [UniProtKB:P47874] synonym: "Olfactory neuronal-specific protein" EXACT [UniProtKB:P47874] xref: EMBL:AAA20485.1 xref: EMBL:AAH69115.1 xref: EMBL:AAH69365.1 xref: UniProtKB:P47874 xref: UniProtKB:Q562G2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019045 ! OMP_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068968 ! OMP_HUMAN-N-acetylalanine2 [Term] id: CCO:B0055388 name: OR3A1_HUMAN def: "Olfactory receptor 3A1" [UniProtKB:P47881] synonym: "Olfactory receptor 17-40" EXACT [UniProtKB:P47881] synonym: "Olfactory receptor OR17-15" EXACT [UniProtKB:P47881] synonym: "OR17-40" EXACT [UniProtKB:P47881] xref: EMBL:AAA18347.1 xref: EMBL:AAF37314.1 xref: EMBL:AAH69414.1 xref: EMBL:AAH96187.1 xref: EMBL:AAH96188.1 xref: EMBL:AAH96189.1 xref: EMBL:AAH96190.1 xref: EMBL:CAA56602.1 xref: EMBL:DAA04636.1 xref: UniProtKB:P47881 xref: UniProtKB:Q4VB06 xref: UniProtKB:Q6IFM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019128 ! OR3A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055389 name: OR3A4_HUMAN def: "Olfactory receptor 3A4" [UniProtKB:P47883] synonym: "Olfactory receptor 17-24" EXACT [UniProtKB:P47883] synonym: "OR17-24" EXACT [UniProtKB:P47883] xref: EMBL:AAA18344.1 xref: EMBL:AAK95106.1 xref: UniProtKB:P47883 xref: UniProtKB:Q96R24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019130 ! OR3A4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055390 name: OR1G1_HUMAN def: "Olfactory receptor 1G1" [UniProtKB:P47890] synonym: "Olfactory receptor 17-209" EXACT [UniProtKB:P47890] synonym: "OR17-209" EXACT [UniProtKB:P47890] xref: EMBL:AAA18352.1 xref: EMBL:AAC99556.1 xref: EMBL:AAF37317.1 xref: EMBL:AAH69379.1 xref: EMBL:AAH95520.1 xref: UniProtKB:P47890 xref: UniProtKB:Q4VBM1 xref: UniProtKB:Q9UM76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019067 ! OR1G1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055391 name: OR3A2_HUMAN def: "Olfactory receptor 3A2" [UniProtKB:P47893] synonym: "Olfactory receptor 17-228" EXACT [UniProtKB:P47893] synonym: "OR17-228" EXACT [UniProtKB:P47893] xref: EMBL:AAA17448.1 xref: EMBL:AAF37318.1 xref: UniProtKB:P47893 xref: UniProtKB:Q9P1Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019129 ! OR3A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055392 name: AL1A3_HUMAN def: "Aldehyde dehydrogenase family 1 member A3" [UniProtKB:P47895] synonym: "Aldehyde dehydrogenase 6" EXACT [UniProtKB:P47895] synonym: "EC 1.2.1.5" EXACT [UniProtKB:P47895] synonym: "RALDH-3" EXACT [UniProtKB:P47895] synonym: "Retinaldehyde dehydrogenase 3" EXACT [UniProtKB:P47895] xref: EMBL:AAA79036.1 xref: EMBL:AAH69274.1 xref: UniProtKB:P47895 xref: UniProtKB:Q6NT64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016950 ! ALDH1A3_human relationship: has_function CCO:F0000506 ! 3-chloroallyl aldehyde dehydrogenase activity relationship: has_function CCO:F0000508 ! aldehyde dehydrogenase [NAD(P)+] activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0055393 name: 5HT5A_HUMAN def: "5-hydroxytryptamine receptor 5A" [UniProtKB:P47898] synonym: "5-HT-5" EXACT [UniProtKB:P47898] synonym: "5-HT-5A" EXACT [UniProtKB:P47898] synonym: "Serotonin receptor 5A" EXACT [UniProtKB:P47898] xref: EMBL:AAI12022.1 xref: EMBL:AAM21132.1 xref: EMBL:CAA57168.1 xref: UniProtKB:P47898 xref: UniProtKB:Q2M2D2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016857 ! HTR5A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055394 name: P2RY1_HUMAN def: "P2Y purinoceptor 1" [UniProtKB:P47900] synonym: "ATP receptor" EXACT [UniProtKB:P47900] synonym: "P2Y1" EXACT [UniProtKB:P47900] synonym: "Purinergic receptor" EXACT [UniProtKB:P47900] xref: EMBL:AAA97872.1 xref: EMBL:AAA97873.1 xref: EMBL:AAB47091.1 xref: EMBL:AAB94556.1 xref: EMBL:AAH74784.1 xref: EMBL:AAH74785.1 xref: EMBL:AAN01278.1 xref: EMBL:CAA07339.1 xref: EMBL:CAA89066.1 xref: UniProtKB:P47900 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019265 ! P2RY1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: transforms_into CCO:B0069017 ! P2RY1_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0069018 ! P2RY1_HUMAN-Phosphoserine354 [Term] id: CCO:B0055395 name: V1BR_HUMAN def: "Vasopressin V1b receptor" [UniProtKB:P47901] synonym: "Antidiuretic hormone receptor 1b" EXACT [UniProtKB:P47901] synonym: "AVPR V1b" EXACT [UniProtKB:P47901] synonym: "AVPR V3" EXACT [UniProtKB:P47901] synonym: "V1bR" EXACT [UniProtKB:P47901] synonym: "Vasopressin V3 receptor" EXACT [UniProtKB:P47901] xref: EMBL:AAA65687.1 xref: EMBL:AAB84293.1 xref: EMBL:AAD17892.1 xref: EMBL:AAF33681.1 xref: EMBL:ABA03171.1 xref: EMBL:BAA06621.1 xref: EMBL:CAH73262.1 xref: UniProtKB:P47901 xref: UniProtKB:Q5TZ00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020429 ! AVPR1B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001338 ! vasopressin receptor activity relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0003529 ! peptide hormone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity [Term] id: CCO:B0055396 name: XDH_HUMAN def: "Xanthine dehydrogenase/oxidase" [UniProtKB:P47989] xref: EMBL:AAA75287.1 xref: EMBL:AAB08399.1 xref: EMBL:AAY68219.1 xref: EMBL:BAA02013.2 xref: UniProtKB:P47989 xref: UniProtKB:Q16681 xref: UniProtKB:Q16712 xref: UniProtKB:Q4PJ16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020509 ! XDH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001342 ! regulation of epithelial cell differentiation relationship: transforms_into CCO:B0071888 ! XDH_HUMAN-Phosphothreonine222 [Term] id: CCO:B0055397 name: XCL1_HUMAN def: "Lymphotactin precursor" [UniProtKB:P47992] synonym: "ATAC" EXACT [UniProtKB:P47992] synonym: "C motif chemokine 1" EXACT [UniProtKB:P47992] synonym: "Cytokine SCM-1" EXACT [UniProtKB:P47992] synonym: "Lymphotaxin" EXACT [UniProtKB:P47992] synonym: "SCM-1-alpha" EXACT [UniProtKB:P47992] synonym: "Small-inducible cytokine C1" EXACT [UniProtKB:P47992] synonym: "XC chemokine ligand 1" EXACT [UniProtKB:P47992] xref: EMBL:AAC50164.1 xref: EMBL:AAH69817.1 xref: EMBL:AAH70309.1 xref: EMBL:BAA07825.1 xref: EMBL:BAA09859.1 xref: EMBL:CAA60198.1 xref: EMBL:CAB46691.1 xref: UniProtKB:P47992 xref: UniProtKB:Q52MA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020506 ! XCL1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055398 name: TNFL6_HUMAN def: "Tumor necrosis factor ligand superfamily member 6" [UniProtKB:P48023] synonym: "Apoptosis antigen ligand" EXACT [UniProtKB:P48023] synonym: "APTL" EXACT [UniProtKB:P48023] synonym: "CD178 antigen" EXACT [UniProtKB:P48023] synonym: "CD95L protein" EXACT [UniProtKB:P48023] synonym: "Fas antigen ligand" EXACT [UniProtKB:P48023] synonym: "Fas ligand" EXACT [UniProtKB:P48023] xref: EMBL:AAC50071.1 xref: EMBL:AAC50124.1 xref: EMBL:AAG60017.1 xref: EMBL:AAH17502.1 xref: EMBL:BAA07320.1 xref: EMBL:BAA32542.1 xref: EMBL:CAA61474.1 xref: EMBL:CAB09424.1 xref: UniProtKB:P48023 xref: UniProtKB:Q9BZP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020304 ! FASLG_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017867 ! tnfsf6-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0018610 ! tnfsf6-casp10-2 physical interaction relationship: participates_in CCO:I0019492 ! tnfsf6-casp10-1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055399 name: SDF1_HUMAN def: "Stromal cell-derived factor 1 precursor" [UniProtKB:P48061] synonym: "C-X-C motif chemokine 12" EXACT [UniProtKB:P48061] synonym: "hIRH" EXACT [UniProtKB:P48061] synonym: "PBSF" EXACT [UniProtKB:P48061] synonym: "Pre-B cell growth-stimulating factor" EXACT [UniProtKB:P48061] synonym: "SDF-1" EXACT [UniProtKB:P48061] xref: EMBL:AAA97434.1 xref: EMBL:AAB39332.1 xref: EMBL:AAB39333.1 xref: EMBL:AAB40516.1 xref: EMBL:AAH39893.1 xref: EMBL:AAV49999.1 xref: EMBL:CAC10202.1 xref: EMBL:CAC10203.1 xref: UniProtKB:P48061 xref: UniProtKB:Q9H554 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019859 ! CXCL12_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000811 ! regulation of actin polymerization and/or depolymerization [Term] id: CCO:B0055400 name: T4S4_HUMAN def: "Transmembrane 4 L6 family member 4" [UniProtKB:P48230] synonym: "IL-TMP" EXACT [UniProtKB:P48230] synonym: "Intestine and liver tetraspan membrane protein" EXACT [UniProtKB:P48230] xref: EMBL:AAA74745.1 xref: EMBL:AAH01386.1 xref: EMBL:AAP36098.1 xref: UniProtKB:P48230 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020111 ! TM4SF4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055401 name: REG1B_HUMAN def: "Lithostathine-1-beta precursor" [UniProtKB:P48304] synonym: "Regenerating protein I beta" EXACT [UniProtKB:P48304] xref: EMBL:AAA18204.1 xref: EMBL:AAH27895.1 xref: EMBL:BAA04091.1 xref: EMBL:BAA04124.1 xref: UniProtKB:P48304 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019664 ! REG1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020146 ! reg1b-bat3 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0069855 ! REG1B_HUMAN-Pyrrolidone carboxylic acid23 [Term] id: CCO:B0055402 name: RFX5_HUMAN def: "DNA-binding protein RFX5" [UniProtKB:P48382] synonym: "Regulatory factor X 5" EXACT [UniProtKB:P48382] xref: EMBL:AAH17471.1 xref: EMBL:CAA59771.1 xref: EMBL:CAH70327.1 xref: UniProtKB:P48382 xref: UniProtKB:Q5VWC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019687 ! RFX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018640 ! hdac2-rfx5 physical interaction relationship: participates_in CCO:I0018641 ! hdac2-rfx5-1 physical interaction relationship: participates_in CCO:I0019456 ! hdac2-rfx5-2 physical interaction relationship: participates_in CCO:I0019457 ! hdac2-rfx5-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055403 name: SOX9_HUMAN def: "Transcription factor SOX-9" [UniProtKB:P48436] xref: EMBL:AAB32870.1 xref: EMBL:AAH07951.1 xref: EMBL:AAH56420.1 xref: EMBL:CAA86598.1 xref: UniProtKB:P48436 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019995 ! SOX9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055404 name: GSH1_HUMAN def: "Glutamate--cysteine ligase catalytic subunit" [UniProtKB:P48506] synonym: "EC 6.3.2.2" EXACT [UniProtKB:P48506] synonym: "Gamma-ECS" EXACT [UniProtKB:P48506] synonym: "Gamma-glutamylcysteine synthetase" EXACT [UniProtKB:P48506] synonym: "GCS heavy chain" EXACT [UniProtKB:P48506] xref: EMBL:AAA58499.1 xref: EMBL:AAC41751.1 xref: EMBL:AAD18031.1 xref: EMBL:AAH22487.1 xref: EMBL:AAH39894.1 xref: EMBL:AAV31778.1 xref: UniProtKB:P48506 xref: UniProtKB:Q14399 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018085 ! GCLC_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000776 ! glutamate-cysteine ligase activity relationship: has_function CCO:F0003210 ! glutamate binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005867 ! ADP binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007988 ! coenzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000840 ! glutamate-cysteine ligase complex relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis relationship: participates_in CCO:P0001431 ! negative regulation of protein ubiquitination relationship: participates_in CCO:P0001617 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process relationship: participates_in CCO:P0003160 ! regulation of mitochondrial depolarization [Term] id: CCO:B0055405 name: GSH0_HUMAN def: "Glutamate--cysteine ligase regulatory subunit" [UniProtKB:P48507] synonym: "Gamma-ECS regulatory subunit" EXACT [UniProtKB:P48507] synonym: "Gamma-glutamylcysteine synthetase regulatory subunit" EXACT [UniProtKB:P48507] synonym: "GCS light chain" EXACT [UniProtKB:P48507] synonym: "Glutamate--cysteine ligase modifier subunit" EXACT [UniProtKB:P48507] xref: EMBL:AAA65028.1 xref: EMBL:AAH41809.1 xref: EMBL:AAV28733.1 xref: EMBL:CAG46632.1 xref: EMBL:CAI21813.1 xref: EMBL:CAI22976.1 xref: UniProtKB:P48507 xref: UniProtKB:Q6FHC1 xref: UniProtKB:Q9NPX9 xref: UniProtKB:Q9NU74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018084 ! GCLM_human relationship: has_function CCO:F0000776 ! glutamate-cysteine ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0005570 ! glutamate-cysteine ligase catalytic subunit binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000840 ! glutamate-cysteine ligase complex relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002233 ! negative regulation of neuron apoptosis relationship: participates_in CCO:P0003160 ! regulation of mitochondrial depolarization [Term] id: CCO:B0055406 name: INAR2_HUMAN def: "Interferon-alpha/beta receptor beta chain precursor" [UniProtKB:P48551] synonym: "IFN-alpha-REC" EXACT [UniProtKB:P48551] synonym: "IFN-R" EXACT [UniProtKB:P48551] synonym: "Interferon alpha/beta receptor 2" EXACT [UniProtKB:P48551] synonym: "Type I interferon receptor" EXACT [UniProtKB:P48551] xref: EMBL:AAB46413.1 xref: EMBL:AAB46414.1 xref: EMBL:AAB46415.1 xref: EMBL:AAB46417.1 xref: EMBL:AAB46418.1 xref: EMBL:AAB46419.1 xref: EMBL:AAC50202.1 xref: EMBL:AAU21038.1 xref: EMBL:CAA54785.1 xref: EMBL:CAA61914.1 xref: UniProtKB:P48551 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018284 ! IFNAR2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008346 ! type I interferon receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015975 ! ifnar2-gnb2l1-4 physical interaction relationship: participates_in CCO:I0017707 ! ifnar2-gnb2l1-3 physical interaction relationship: participates_in CCO:I0017924 ! ifnar2-gnb2l1-2 physical interaction relationship: participates_in CCO:I0018373 ! ifnar2-gnb2l1-1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:B0055407 name: NRIP1_HUMAN def: "Nuclear receptor-interacting protein 1" [UniProtKB:P48552] synonym: "Nuclear factor RIP140" EXACT [UniProtKB:P48552] synonym: "Receptor-interacting protein 140" EXACT [UniProtKB:P48552] xref: EMBL:AAF35255.1 xref: EMBL:AAF62185.1 xref: EMBL:AAH40361.1 xref: EMBL:CAA59108.1 xref: EMBL:CAB90396.1 xref: UniProtKB:P48552 xref: UniProtKB:Q8IWE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018869 ! NRIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015253 ! ldoc1-nrip1 physical interaction relationship: participates_in CCO:I0015391 ! nrip1-tex11 physical interaction relationship: participates_in CCO:I0015585 ! cep70-nrip1 physical interaction relationship: participates_in CCO:I0015610 ! ctbp2-nrip1 physical interaction relationship: participates_in CCO:I0015669 ! nrip1-traf2 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068837 ! NRIP1_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0068838 ! NRIP1_HUMAN-N6-acetyllysine111 relationship: transforms_into CCO:B0068839 ! NRIP1_HUMAN-N6-acetyllysine158 relationship: transforms_into CCO:B0068840 ! NRIP1_HUMAN-Phosphothreonine207 relationship: transforms_into CCO:B0068841 ! NRIP1_HUMAN-N6-acetyllysine286 relationship: transforms_into CCO:B0068842 ! NRIP1_HUMAN-N6-acetyllysine310 relationship: transforms_into CCO:B0068843 ! NRIP1_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0068844 ! NRIP1_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0068845 ! NRIP1_HUMAN-N6-acetyllysine446 relationship: transforms_into CCO:B0068846 ! NRIP1_HUMAN-N6-acetyllysine481 relationship: transforms_into CCO:B0068847 ! NRIP1_HUMAN-Phosphoserine487 relationship: transforms_into CCO:B0068848 ! NRIP1_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0068849 ! NRIP1_HUMAN-N6-acetyllysine528 relationship: transforms_into CCO:B0068850 ! NRIP1_HUMAN-Phosphoserine542 relationship: transforms_into CCO:B0068851 ! NRIP1_HUMAN-N6-acetyllysine606 relationship: transforms_into CCO:B0068852 ! NRIP1_HUMAN-Phosphoserine671 relationship: transforms_into CCO:B0068853 ! NRIP1_HUMAN-Phosphothreonine731 relationship: transforms_into CCO:B0068854 ! NRIP1_HUMAN-N6-acetyllysine931 relationship: transforms_into CCO:B0068855 ! NRIP1_HUMAN-Phosphoserine1001 [Term] id: CCO:B0055408 name: SPB4_HUMAN def: "Serpin B4" [UniProtKB:P48594] synonym: "Leupin" EXACT [UniProtKB:P48594] synonym: "SCCA-2" EXACT [UniProtKB:P48594] synonym: "Squamous cell carcinoma antigen 2" EXACT [UniProtKB:P48594] xref: EMBL:AAA92602.1 xref: EMBL:AAA97553.1 xref: EMBL:AAH17401.1 xref: EMBL:BAB21525.1 xref: EMBL:CAA61420.1 xref: UniProtKB:P48594 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020008 ! SERPINB4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001246 ! regulation of proteolysis relationship: transforms_into CCO:B0070790 ! SPB4_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0055409 name: NMU_HUMAN def: "Neuromedin-U precursor" [UniProtKB:P48645] xref: EMBL:AAH12908.1 xref: EMBL:CAA53619.1 xref: UniProtKB:P48645 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018812 ! NMU_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0068755 ! NMU_HUMAN-Asparagine amide166 [Term] id: CCO:B0055410 name: KC1A_HUMAN def: "Casein kinase I isoform alpha" [UniProtKB:P48729] synonym: "CK1" EXACT [UniProtKB:P48729] synonym: "CKI-alpha" EXACT [UniProtKB:P48729] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P48729] xref: EMBL:AAC41760.1 xref: EMBL:AAH08717.1 xref: EMBL:AAV38632.1 xref: EMBL:AAV38633.1 xref: EMBL:AAY84562.1 xref: EMBL:CAA56710.1 xref: EMBL:CAG47002.1 xref: EMBL:EAW61769.1 xref: UniProtKB:P48729 xref: UniProtKB:Q4JJA0 xref: UniProtKB:Q5U046 xref: UniProtKB:Q5U047 xref: UniProtKB:Q6FGA2 xref: UniProtKB:Q96HD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018379 ! CSNK1A1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001051 ! casein kinase I activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0067260 ! KC1A_HUMAN-Phosphothreonine321 [Term] id: CCO:B0055411 name: LHX1_HUMAN def: "LIM/homeobox protein Lhx1" [UniProtKB:P48742] synonym: "hLim-1" EXACT [UniProtKB:P48742] synonym: "Homeobox protein Lim-1" EXACT [UniProtKB:P48742] synonym: "LIM homeobox protein 1" EXACT [UniProtKB:P48742] xref: EMBL:AAA21644.1 xref: EMBL:AAI01675.1 xref: EMBL:AAI11937.1 xref: UniProtKB:P48742 xref: UniProtKB:Q3MIW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018485 ! LHX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055412 name: TNNI2_HUMAN def: "Troponin I, fast skeletal muscle" [UniProtKB:P48788] synonym: "Troponin I, fast-twitch isoform" EXACT [UniProtKB:P48788] xref: EMBL:AAA19813.1 xref: EMBL:AAH32148.1 xref: EMBL:CAB59981.1 xref: UniProtKB:A6NJU5 xref: UniProtKB:P48788 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020309 ! TNNI2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004626 ! troponin T binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000424 ! troponin complex relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0055413 name: CD97_HUMAN def: "CD97 antigen precursor" [UniProtKB:P48960] synonym: "CD97 antigen" EXACT [UniProtKB:P48960] synonym: "Leukocyte antigen CD97" EXACT [UniProtKB:P48960] xref: EMBL:AAB36682.1 xref: EMBL:AAC27673.1 xref: EMBL:AAH26690.1 xref: EMBL:BAC06178.1 xref: EMBL:CAA59173.1 xref: EMBL:CAA64333.1 xref: UniProtKB:O00718 xref: UniProtKB:O76101 xref: UniProtKB:P48960 xref: UniProtKB:Q8NG72 xref: UniProtKB:Q8TBQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017316 ! CD97_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0064176 ! CD97_HUMAN-Phosphoserine831 relationship: transforms_into CCO:B0064177 ! CD97_HUMAN-Phosphoserine833 [Term] id: CCO:B0055414 name: G109B_HUMAN def: "Nicotinic acid receptor 2" [UniProtKB:P49019] synonym: "G-protein coupled receptor 109B" EXACT [UniProtKB:P49019] synonym: "G-protein coupled receptor HM74" EXACT [UniProtKB:P49019] synonym: "G-protein coupled receptor HM74B" EXACT [UniProtKB:P49019] xref: EMBL:AAH47891.1 xref: EMBL:ABX64359.1 xref: EMBL:BAA01721.1 xref: EMBL:BAC06083.1 xref: EMBL:BAF83619.1 xref: UniProtKB:A8K4G5 xref: UniProtKB:P49019 xref: UniProtKB:Q8NGE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017856 ! GPR109B_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055415 name: CAMLG_HUMAN def: "Calcium signal-modulating cyclophilin ligand" [UniProtKB:P49069] synonym: "CAML" EXACT [UniProtKB:P49069] xref: EMBL:AAA59420.1 xref: EMBL:AAC23596.1 xref: UniProtKB:P49069 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017220 ! CAMLG_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000486 ! receptor recycling relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway [Term] id: CCO:B0055416 name: NR2C2_HUMAN def: "Nuclear receptor subfamily 2 group C member 2" [UniProtKB:P49116] synonym: "Orphan nuclear receptor TAK1" EXACT [UniProtKB:P49116] synonym: "Orphan nuclear receptor TR4" EXACT [UniProtKB:P49116] synonym: "Testicular receptor 4" EXACT [UniProtKB:P49116] xref: EMBL:AAA21474.1 xref: EMBL:AAC50118.1 xref: UniProtKB:P49116 xref: UniProtKB:P55092 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018857 ! NR2C2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068818 ! NR2C2_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0068819 ! NR2C2_HUMAN-Phosphothreonine224 [Term] id: CCO:B0055417 name: MAPK2_HUMAN def: "MAP kinase-activated protein kinase 2" [UniProtKB:P49137] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P49137] synonym: "MAPK-activated protein kinase 2" EXACT [UniProtKB:P49137] synonym: "MAPKAP kinase 2" EXACT [UniProtKB:P49137] synonym: "MAPKAPK-2" EXACT [UniProtKB:P49137] synonym: "MK2" EXACT [UniProtKB:P49137] xref: EMBL:AAA20851.1 xref: EMBL:AAH36060.2 xref: EMBL:AAH52584.1 xref: EMBL:CAA53094.1 xref: UniProtKB:P49137 xref: UniProtKB:Q8IYD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018568 ! MAPKAPK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016195 ! hsf1-mk2-2 phosphorylation relationship: participates_in CCO:I0017779 ! hsf1-mk2-1 phosphorylation relationship: participates_in CCO:I0017942 ! mk2-hsf1 physical interaction relationship: participates_in CCO:I0018563 ! hsf1-mk2 physical interaction relationship: participates_in CCO:I0019312 ! hsf1-mk2-3 physical interaction relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0067984 ! MAPK2_HUMAN-Phosphotyrosine63 relationship: transforms_into CCO:B0067985 ! MAPK2_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0067986 ! MAPK2_HUMAN-Phosphothreonine334 relationship: transforms_into CCO:B0067987 ! MAPK2_HUMAN-Phosphothreonine338 [Term] id: CCO:B0055418 name: NPY2R_HUMAN def: "Neuropeptide Y receptor type 2" [UniProtKB:P49146] synonym: "NPY-Y2 receptor" EXACT [UniProtKB:P49146] synonym: "NPY2-R" EXACT [UniProtKB:P49146] synonym: "Y2 receptor" EXACT [UniProtKB:P49146] xref: EMBL:AAA93170.1 xref: EMBL:AAB04120.1 xref: EMBL:AAB07760.1 xref: EMBL:AAC50281.1 xref: EMBL:AAC51115.1 xref: EMBL:AAD00248.1 xref: EMBL:AAH75052.2 xref: EMBL:AAH75053.2 xref: EMBL:AAO92062.1 xref: UniProtKB:P49146 xref: UniProtKB:Q13281 xref: UniProtKB:Q13457 xref: UniProtKB:Q6AZZ6 xref: UniProtKB:Q9UE67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018843 ! NPY2R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000156 ! peptide YY receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_function CCO:F0001514 ! calcium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway [Term] id: CCO:B0055419 name: PTH2R_HUMAN def: "Parathyroid hormone 2 receptor precursor" [UniProtKB:P49190] synonym: "PTH2 receptor" EXACT [UniProtKB:P49190] xref: EMBL:AAA96796.1 xref: EMBL:AAC50157.1 xref: EMBL:AAC50767.1 xref: EMBL:AAH36811.2 xref: EMBL:AAR90849.1 xref: UniProtKB:P49190 xref: UniProtKB:Q8N429 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019541 ! PTH2R_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001329 ! parathyroid hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055420 name: CX3C1_HUMAN def: "CX3C chemokine receptor 1" [UniProtKB:P49238] synonym: "Beta chemokine receptor-like 1" EXACT [UniProtKB:P49238] synonym: "C-X3-C CKR-1" EXACT [UniProtKB:P49238] synonym: "CMK-BRL-1" EXACT [UniProtKB:P49238] synonym: "CMKBLR1" EXACT [UniProtKB:P49238] synonym: "CX3CR1" EXACT [UniProtKB:P49238] synonym: "Fractalkine receptor" EXACT [UniProtKB:P49238] synonym: "G-protein coupled receptor 13" EXACT [UniProtKB:P49238] synonym: "V28" EXACT [UniProtKB:P49238] xref: EMBL:AAA87032.1 xref: EMBL:AAA91783.1 xref: EMBL:AAH28078.1 xref: EMBL:AAK08627.1 xref: UniProtKB:P49238 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017494 ! CX3CR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055421 name: FNTA_HUMAN def: "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha" [UniProtKB:P49354] synonym: "CAAX farnesyltransferase subunit alpha" EXACT [UniProtKB:P49354] synonym: "EC 2.5.1.58" EXACT [UniProtKB:P49354] synonym: "EC 2.5.1.59" EXACT [UniProtKB:P49354] synonym: "FTase-alpha" EXACT [UniProtKB:P49354] synonym: "GGTase-I-alpha" EXACT [UniProtKB:P49354] synonym: "Ras proteins prenyltransferase alpha" EXACT [UniProtKB:P49354] synonym: "Type I protein geranyl-geranyltransferase subunit alpha" EXACT [UniProtKB:P49354] xref: EMBL:AAA35853.1 xref: EMBL:AAA86285.1 xref: EMBL:AAH17029.2 xref: EMBL:AAH84566.1 xref: UniProtKB:P49354 xref: UniProtKB:Q9UDC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017817 ! FNTA_human relationship: has_function CCO:F0001032 ! prenyltransferase activity relationship: has_function CCO:F0001033 ! protein farnesyltransferase activity relationship: has_function CCO:F0001034 ! protein geranylgeranyltransferase activity relationship: has_function CCO:F0001035 ! CAAX-protein geranylgeranyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001830 ! protein prenyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0017420 ! fnta-fntb-14 direct interaction relationship: participates_in CCO:I0018117 ! fnta-fntb-2 direct interaction relationship: participates_in CCO:I0018708 ! fnta-fntb-16 direct interaction relationship: participates_in CCO:I0018748 ! fnta-fntb-3 direct interaction relationship: participates_in CCO:I0018749 ! fnta-fntb-4 direct interaction relationship: participates_in CCO:I0019380 ! pfta-rap2-1 physical interaction relationship: participates_in CCO:I0019478 ! fnta-fntb-13 direct interaction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: transforms_into CCO:B0066234 ! FNTA_HUMAN-Phosphoserine373 [Term] id: CCO:B0055422 name: FNTB_HUMAN def: "Protein farnesyltransferase subunit beta" [UniProtKB:P49356] synonym: "CAAX farnesyltransferase subunit beta" EXACT [UniProtKB:P49356] synonym: "EC 2.5.1.58" EXACT [UniProtKB:P49356] synonym: "FTase-beta" EXACT [UniProtKB:P49356] synonym: "RAS proteins prenyltransferase beta" EXACT [UniProtKB:P49356] xref: EMBL:AAA35854.1 xref: EMBL:AAA86286.1 xref: EMBL:AAH20232.1 xref: UniProtKB:P49356 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0007967 ! FNTB_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000732 ! farnesyltranstransferase activity relationship: has_function CCO:F0001032 ! prenyltransferase activity relationship: has_function CCO:F0001033 ! protein farnesyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017420 ! fnta-fntb-14 direct interaction relationship: participates_in CCO:I0018117 ! fnta-fntb-2 direct interaction relationship: participates_in CCO:I0018708 ! fnta-fntb-16 direct interaction relationship: participates_in CCO:I0018748 ! fnta-fntb-3 direct interaction relationship: participates_in CCO:I0018749 ! fnta-fntb-4 direct interaction relationship: participates_in CCO:I0019380 ! pfta-rap2-1 physical interaction relationship: participates_in CCO:I0019478 ! fnta-fntb-13 direct interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002782 ! positive regulation of fibroblast proliferation relationship: transforms_into CCO:B0066235 ! FNTB_HUMAN-Phosphotyrosine300 [Term] id: CCO:B0055423 name: DHYS_HUMAN def: "Deoxyhypusine synthase" [UniProtKB:P49366] synonym: "DHS" EXACT [UniProtKB:P49366] synonym: "EC 2.5.1.46" EXACT [UniProtKB:P49366] xref: EMBL:AAA86282.1 xref: EMBL:AAA96151.1 xref: EMBL:AAB02175.1 xref: EMBL:AAB02179.1 xref: EMBL:AAB50208.1 xref: EMBL:AAH00333.1 xref: EMBL:AAH14016.1 xref: EMBL:CAA04940.1 xref: UniProtKB:P49366 xref: UniProtKB:Q13184 xref: UniProtKB:Q13276 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017576 ! DHPS_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005501 ! deoxyhypusine synthase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015024 ! dhps-nif3l1 physical interaction relationship: participates_in CCO:I0015380 ! dhps-eif5a2 physical interaction relationship: participates_in CCO:I0015397 ! dhps-rpl9 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0064762 ! DHYS_HUMAN-Phosphoserine78 relationship: transforms_into CCO:B0064763 ! DHYS_HUMAN-Phosphothreonine88 [Term] id: CCO:B0055424 name: ARRB1_HUMAN def: "Beta-arrestin-1" [UniProtKB:P49407] synonym: "Arrestin beta-1" EXACT [UniProtKB:P49407] xref: EMBL:AAA35558.1 xref: EMBL:AAA35559.1 xref: EMBL:AAC33295.1 xref: EMBL:AAC34123.1 xref: EMBL:AAH03636.1 xref: EMBL:ABC40724.1 xref: UniProtKB:O75625 xref: UniProtKB:O75630 xref: UniProtKB:P49407 xref: UniProtKB:Q2PP20 xref: UniProtKB:Q9BTK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017049 ! ARRB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015057 ! arrb1-znf297b physical interaction relationship: participates_in CCO:I0015298 ! arrb1-gnmt physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0063614 ! ARRB1_HUMAN-Phosphotyrosine47 relationship: transforms_into CCO:B0063615 ! ARRB1_HUMAN-Phosphothreonine410 relationship: transforms_into CCO:B0063616 ! ARRB1_HUMAN-Phosphoserine412 [Term] id: CCO:B0055425 name: DGKG_HUMAN def: "Diacylglycerol kinase gamma" [UniProtKB:P49619] synonym: "DAG kinase gamma" EXACT [UniProtKB:P49619] synonym: "DGK-gamma" EXACT [UniProtKB:P49619] synonym: "Diglyceride kinase gamma" EXACT [UniProtKB:P49619] synonym: "EC 2.7.1.107" EXACT [UniProtKB:P49619] xref: EMBL:AAC04686.1 xref: EMBL:BAA05132.1 xref: UniProtKB:P49619 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017568 ! DGKG_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055426 name: HXA1_HUMAN def: "Homeobox protein Hox-A1" [UniProtKB:P49639] synonym: "Hox-1F" EXACT [UniProtKB:P49639] xref: EMBL:AAA86954.1 xref: EMBL:AAB35423.2 xref: EMBL:AAB35424.2 xref: EMBL:AAB35425.1 xref: EMBL:AAC50248.1 xref: EMBL:AAC50249.1 xref: EMBL:AAC50250.1 xref: EMBL:AAH32547.1 xref: EMBL:AAS00374.1 xref: UniProtKB:O43363 xref: UniProtKB:P49639 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018178 ! HOXA1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014981 ! hoxa1-mdfi physical interaction relationship: participates_in CCO:I0015020 ! hoxa1-plscr1 physical interaction relationship: participates_in CCO:I0015269 ! chic2-hoxa1 physical interaction relationship: participates_in CCO:I0015458 ! hoxa1-krtap4_12 physical interaction relationship: participates_in CCO:I0015617 ! efemp2-hoxa1 physical interaction relationship: participates_in CCO:I0015662 ! hoxa1-lpxn physical interaction relationship: participates_in CCO:I0015782 ! grn-hoxa1 physical interaction relationship: participates_in CCO:I0015798 ! hoxa1-trip6 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055427 name: EVX1_HUMAN def: "Homeobox even-skipped homolog protein 1" [UniProtKB:P49640] synonym: "EVX-1" EXACT [UniProtKB:P49640] xref: EMBL:AAB07598.1 xref: EMBL:CAA43062.1 xref: UniProtKB:P49640 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017744 ! EVX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055428 name: CXCR3_HUMAN def: "C-X-C chemokine receptor type 3" [UniProtKB:P49682] synonym: "CD183 antigen" EXACT [UniProtKB:P49682] synonym: "CKR-L2" EXACT [UniProtKB:P49682] synonym: "CXC-R3" EXACT [UniProtKB:P49682] synonym: "CXCR-3" EXACT [UniProtKB:P49682] synonym: "G protein-coupled receptor 9" EXACT [UniProtKB:P49682] synonym: "Interferon-inducible protein 10 receptor" EXACT [UniProtKB:P49682] synonym: "IP-10 receptor" EXACT [UniProtKB:P49682] xref: EMBL:AAC50505.1 xref: EMBL:AAH34403.1 xref: EMBL:AAO92295.1 xref: EMBL:AAP55851.1 xref: EMBL:BAA92297.1 xref: EMBL:BAA92298.1 xref: EMBL:CAA65126.1 xref: EMBL:CAB02143.1 xref: UniProtKB:O15185 xref: UniProtKB:P49682 xref: UniProtKB:Q7Z710 xref: UniProtKB:Q9P2T4 xref: UniProtKB:Q9P2T5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017499 ! CXCR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055429 name: PRLHR_HUMAN def: "Prolactin-releasing peptide receptor" [UniProtKB:P49683] synonym: "G-protein coupled receptor 10" EXACT [UniProtKB:P49683] synonym: "hGR3" EXACT [UniProtKB:P49683] synonym: "PrRP receptor" EXACT [UniProtKB:P49683] synonym: "PrRPR" EXACT [UniProtKB:P49683] xref: EMBL:AAC50504.1 xref: EMBL:AAH95539.1 xref: EMBL:AAI01491.1 xref: EMBL:AAI01493.1 xref: EMBL:BAA31159.1 xref: EMBL:BAB83030.1 xref: EMBL:CAH73066.1 xref: UniProtKB:O75194 xref: UniProtKB:P49683 xref: UniProtKB:Q502U8 xref: UniProtKB:Q5VXR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019511 ! PRLHR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055430 name: GPR15_HUMAN def: "G-protein coupled receptor 15" [UniProtKB:P49685] synonym: "BOB" EXACT [UniProtKB:P49685] xref: EMBL:AAC50826.1 xref: EMBL:AAH69437.1 xref: EMBL:AAI01780.1 xref: EMBL:AAI01782.1 xref: UniProtKB:P49685 xref: UniProtKB:Q3MIL4 xref: UniProtKB:Q6ISN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018003 ! GPR15_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055431 name: CEBPA_HUMAN def: "CCAAT/enhancer-binding protein alpha" [UniProtKB:P49715] synonym: "C/EBP alpha" EXACT [UniProtKB:P49715] xref: EMBL:AAC50235.1 xref: EMBL:AAH27902.1 xref: EMBL:ABS82765.1 xref: EMBL:CAA72289.1 xref: UniProtKB:A7LNP2 xref: UniProtKB:P49715 xref: UniProtKB:P78319 xref: UniProtKB:Q05CA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017324 ! CEBPA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0055432 name: CEBPD_HUMAN def: "CCAAT/enhancer-binding protein delta" [UniProtKB:P49716] synonym: "C/EBP delta" EXACT [UniProtKB:P49716] synonym: "NF-IL6-beta" EXACT [UniProtKB:P49716] synonym: "Nuclear factor NF-IL6-beta" EXACT [UniProtKB:P49716] xref: EMBL:AAA59927.1 xref: EMBL:AAB27293.1 xref: EMBL:AAI05110.1 xref: EMBL:EAW86679.1 xref: UniProtKB:P49716 xref: UniProtKB:Q14937 xref: UniProtKB:Q2M2X9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017325 ! CEBPD_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055433 name: RGS6_HUMAN def: "Regulator of G-protein signaling 6" [UniProtKB:P49758] synonym: "RGS6" EXACT [UniProtKB:P49758] synonym: "S914" EXACT [UniProtKB:P49758] xref: EMBL:AAC26049.2 xref: EMBL:AAC26050.1 xref: EMBL:AAC42001.1 xref: EMBL:AAC83180.1 xref: EMBL:AAD05031.1 xref: EMBL:AAD34717.1 xref: EMBL:AAD34718.1 xref: EMBL:AAD40183.1 xref: EMBL:AAM03004.1 xref: EMBL:AAM03005.1 xref: EMBL:AAM03006.1 xref: EMBL:AAM03007.1 xref: EMBL:AAM03008.1 xref: EMBL:AAM03009.1 xref: EMBL:AAM03010.1 xref: EMBL:AAM03011.1 xref: EMBL:AAM03012.1 xref: EMBL:AAM03013.1 xref: UniProtKB:O75576 xref: UniProtKB:O75577 xref: UniProtKB:P49758 xref: UniProtKB:Q8TE13 xref: UniProtKB:Q8TE14 xref: UniProtKB:Q8TE15 xref: UniProtKB:Q8TE16 xref: UniProtKB:Q8TE17 xref: UniProtKB:Q8TE18 xref: UniProtKB:Q8TE19 xref: UniProtKB:Q8TE20 xref: UniProtKB:Q8TE21 xref: UniProtKB:Q8TE22 xref: UniProtKB:Q9UDS8 xref: UniProtKB:Q9UDT0 xref: UniProtKB:Q9Y245 xref: UniProtKB:Q9Y647 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019704 ! RGS6_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0003112 ! regulator of G-protein signaling activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0055434 name: EI2BB_HUMAN def: "Translation initiation factor eIF-2B subunit beta" [UniProtKB:P49770] synonym: "eIF-2B GDP-GTP exchange factor subunit beta" EXACT [UniProtKB:P49770] synonym: "S20I15" EXACT [UniProtKB:P49770] synonym: "S20III15" EXACT [UniProtKB:P49770] xref: EMBL:AAB88176.1 xref: EMBL:AAC42002.1 xref: EMBL:AAD30183.1 xref: EMBL:AAH11750.1 xref: UniProtKB:O43201 xref: UniProtKB:P49770 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017670 ! EIF2B2_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000417 ! eukaryotic translation initiation factor 2B complex relationship: participates_in CCO:I0020270 ! cct3-eif2b2 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation [Term] id: CCO:B0055435 name: FLT3L_HUMAN def: "SL cytokine precursor" [UniProtKB:P49771] synonym: "Flt3 ligand" EXACT [UniProtKB:P49771] synonym: "Flt3L" EXACT [UniProtKB:P49771] synonym: "Fms-related tyrosine kinase 3 ligand" EXACT [UniProtKB:P49771] xref: EMBL:AAA17999.1 xref: EMBL:AAA19825.1 xref: EMBL:AAA90949.1 xref: EMBL:AAA90950.1 xref: EMBL:AAI26294.1 xref: UniProtKB:A0AVC2 xref: UniProtKB:P49771 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017813 ! FLT3LG_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020560 ! flt3lg-pfn2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055436 name: HINT1_HUMAN def: "Histidine triad nucleotide-binding protein 1" [UniProtKB:P49773] synonym: "Adenosine 5'-monophosphoramidase" EXACT [UniProtKB:P49773] synonym: "EC 3.-.-.-" EXACT [UniProtKB:P49773] synonym: "PKCI-1" EXACT [UniProtKB:P49773] synonym: "Protein kinase C inhibitor 1" EXACT [UniProtKB:P49773] synonym: "Protein kinase C-interacting protein 1" EXACT [UniProtKB:P49773] xref: EMBL:AAA82926.1 xref: EMBL:AAC71077.1 xref: EMBL:AAH01287.1 xref: EMBL:AAH07090.1 xref: EMBL:BAB15500.1 xref: EMBL:CAG33329.1 xref: UniProtKB:P49773 xref: UniProtKB:Q9H5W8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018132 ! HINT1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001385 ! protein kinase C binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066803 ! HINT1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0055437 name: TIG1_HUMAN def: "Retinoic acid receptor responder protein 1" [UniProtKB:P49788] synonym: "RAR-responsive protein TIG1" EXACT [UniProtKB:P49788] synonym: "Tazarotene-induced gene 1 protein" EXACT [UniProtKB:P49788] xref: EMBL:AAA99722.1 xref: EMBL:AAH29640.1 xref: UniProtKB:P49788 xref: UniProtKB:Q8N1D7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020265 ! RARRES1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055438 name: RGS7_HUMAN def: "Regulator of G-protein signaling 7" [UniProtKB:P49802] synonym: "RGS7" EXACT [UniProtKB:P49802] xref: EMBL:AAC50351.1 xref: EMBL:AAD34290.1 xref: EMBL:AAD34291.1 xref: EMBL:AAM12644.1 xref: EMBL:AAM12645.1 xref: EMBL:AAT52231.1 xref: EMBL:CAH71988.1 xref: EMBL:CAH71989.1 xref: EMBL:CAH71990.1 xref: EMBL:CAH73809.1 xref: EMBL:CAH73811.1 xref: EMBL:CAH73812.1 xref: EMBL:CAI15141.1 xref: EMBL:CAI15142.1 xref: EMBL:CAI15143.1 xref: EMBL:CAI16819.1 xref: EMBL:CAI16820.1 xref: EMBL:CAI16821.1 xref: UniProtKB:P49802 xref: UniProtKB:Q8TD66 xref: UniProtKB:Q8TD67 xref: UniProtKB:Q9UNU7 xref: UniProtKB:Q9Y6B9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019705 ! RGS7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0069922 ! RGS7_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0069923 ! RGS7_HUMAN-Phosphoserine434 [Term] id: CCO:B0055439 name: PSN2_HUMAN def: "Presenilin-2" [UniProtKB:P49810] synonym: "AD3LP" EXACT [UniProtKB:P49810] synonym: "AD5" EXACT [UniProtKB:P49810] synonym: "E5-1" EXACT [UniProtKB:P49810] synonym: "EC 3.4.23.-" EXACT [UniProtKB:P49810] synonym: "PS-2" EXACT [UniProtKB:P49810] synonym: "STM-2" EXACT [UniProtKB:P49810] xref: EMBL:AAB50054.1 xref: EMBL:AAB59557.1 xref: EMBL:AAC42012.1 xref: EMBL:AAC50290.1 xref: EMBL:AAH06365.1 xref: EMBL:AAL16812.1 xref: EMBL:AAP35630.1 xref: UniProtKB:P49810 xref: UniProtKB:Q96P32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019531 ! PSEN2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000256 ! integral to nuclear inner membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000755 ! Notch receptor processing relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000839 ! apoptotic program [Term] id: CCO:B0055440 name: TAF6_HUMAN def: "Transcription initiation factor TFIID subunit 6" [UniProtKB:P49848] synonym: "RNA polymerase II TBP-associated factor subunit E" EXACT [UniProtKB:P49848] synonym: "TAF(II)70" EXACT [UniProtKB:P49848] synonym: "TAFII-70" EXACT [UniProtKB:P49848] synonym: "TAFII-80" EXACT [UniProtKB:P49848] synonym: "TAFII80" EXACT [UniProtKB:P49848] synonym: "Transcription initiation factor TFIID 70 kDa subunit" EXACT [UniProtKB:P49848] xref: EMBL:AAA63643.1 xref: EMBL:AAA84390.1 xref: EMBL:AAH18115.1 xref: EMBL:AAN10295.1 xref: UniProtKB:P49848 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008417 ! TAF6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000277 ! transcription factor TFIIE complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0003021 ! regulation of transcription factor activity relationship: transforms_into CCO:B0071101 ! TAF6_HUMAN-Phosphoserine626 relationship: transforms_into CCO:B0071102 ! TAF6_HUMAN-Phosphoserine634 relationship: transforms_into CCO:B0071103 ! TAF6_HUMAN-Phosphoserine636 relationship: transforms_into CCO:B0071104 ! TAF6_HUMAN-Phosphoserine653 relationship: transforms_into CCO:B0071105 ! TAF6_HUMAN-Phosphothreonine660 [Term] id: CCO:B0055441 name: ZN165_HUMAN def: "Zinc finger protein 165" [UniProtKB:P49910] synonym: "Cancer/testis antigen 53" EXACT [UniProtKB:P49910] synonym: "CT53" EXACT [UniProtKB:P49910] synonym: "LD65" EXACT [UniProtKB:P49910] synonym: "Zinc finger and SCAN domain-containing protein 7" EXACT [UniProtKB:P49910] xref: EMBL:AAC51658.1 xref: EMBL:AAD04755.1 xref: EMBL:AAH26092.1 xref: EMBL:CAA59268.1 xref: EMBL:CAB92080.1 xref: UniProtKB:P49910 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020636 ! ZNF165_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015011 ! tceb3b-znf165 physical interaction relationship: participates_in CCO:I0015062 ! myst2-znf165 physical interaction relationship: participates_in CCO:I0015284 ! znf165-znf446 physical interaction relationship: participates_in CCO:I0015381 ! ewsr1-znf165 physical interaction relationship: participates_in CCO:I0015582 ! krtap4_12-znf165 physical interaction relationship: participates_in CCO:I0015638 ! scand1-znf165 physical interaction relationship: participates_in CCO:I0015707 ! pdlim7-znf165 physical interaction relationship: participates_in CCO:I0015801 ! dvl2-znf165 physical interaction relationship: participates_in CCO:I0015808 ! znf165-znf250 physical interaction relationship: participates_in CCO:I0019426 ! dvl2-znf165-1 physical interaction relationship: participates_in CCO:I0019431 ! ewsr1-znf165-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055442 name: AGTR2_HUMAN def: "Type-2 angiotensin II receptor" [UniProtKB:P50052] synonym: "AT2" EXACT [UniProtKB:P50052] xref: EMBL:AAA50762.1 xref: EMBL:AAA61794.1 xref: EMBL:AAA67753.1 xref: EMBL:AAA84900.1 xref: EMBL:AAA85851.1 xref: EMBL:AAA98990.1 xref: EMBL:AAH95504.1 xref: EMBL:AAP72969.1 xref: EMBL:AAP84355.1 xref: EMBL:AAS45437.1 xref: EMBL:CAA61022.1 xref: EMBL:CAG46767.1 xref: EMBL:CAI40984.1 xref: UniProtKB:P50052 xref: UniProtKB:Q13016 xref: UniProtKB:Q6FGY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016934 ! AGTR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_function CCO:F0001289 ! bradykinin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007301 ! receptor antagonist activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000737 ! G-protein signaling, coupled to cGMP nucleotide second messenger relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002238 ! negative regulation of blood vessel endothelial cell migration relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0003083 ! negative regulation of nerve growth factor receptor signaling pathway [Term] id: CCO:B0055443 name: GBG4_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor" [UniProtKB:P50150] xref: EMBL:AAC50204.1 xref: EMBL:AAH22485.1 xref: EMBL:AAM12586.1 xref: UniProtKB:P50150 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017887 ! GNG4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0055444 name: GBG10_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 precursor" [UniProtKB:P50151] xref: EMBL:AAC50205.1 xref: EMBL:AAH10384.1 xref: EMBL:AAH16319.1 xref: EMBL:AAH72671.1 xref: EMBL:AAI07575.1 xref: EMBL:AAM12591.1 xref: EMBL:CAC22155.1 xref: UniProtKB:P50151 xref: UniProtKB:Q3B7K2 xref: UniProtKB:Q4VC27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017880 ! GNG10_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0055445 name: MEOX1_HUMAN def: "Homeobox protein MOX-1" [UniProtKB:P50221] synonym: "Mesenchyme homeobox 1" EXACT [UniProtKB:P50221] xref: EMBL:AAA19983.1 xref: EMBL:AAH69474.1 xref: EMBL:AAH69506.1 xref: UniProtKB:P50221 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018603 ! MEOX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055446 name: MMP14_HUMAN def: "Matrix metalloproteinase-14 precursor" [UniProtKB:P50281] synonym: "EC 3.4.24.80" EXACT [UniProtKB:P50281] synonym: "Membrane-type matrix metalloproteinase 1" EXACT [UniProtKB:P50281] synonym: "Membrane-type-1 matrix metalloproteinase" EXACT [UniProtKB:P50281] synonym: "MMP-14" EXACT [UniProtKB:P50281] synonym: "MMP-X1" EXACT [UniProtKB:P50281] synonym: "MT-MMP 1" EXACT [UniProtKB:P50281] synonym: "MT1-MMP" EXACT [UniProtKB:P50281] synonym: "MT1MMP" EXACT [UniProtKB:P50281] synonym: "MTMMP1" EXACT [UniProtKB:P50281] xref: EMBL:AAA83770.1 xref: EMBL:AAH64803.1 xref: EMBL:AAV40837.1 xref: EMBL:BAA05519.1 xref: EMBL:CAA58519.1 xref: EMBL:CAA62432.1 xref: EMBL:CAA88372.1 xref: UniProtKB:P50281 xref: UniProtKB:Q6GSF3 xref: UniProtKB:Q92678 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018639 ! MMP14_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003185 ! protease activator activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0015991 ! mmp14-adi1-2 physical interaction relationship: participates_in CCO:I0018242 ! mmp14-adi1-1 physical interaction relationship: participates_in CCO:I0018389 ! mmp14-adi1-3 physical interaction relationship: participates_in CCO:I0019461 ! mmp14-adi1-4 colocalization relationship: participates_in CCO:P0000503 ! endothelial cell proliferation relationship: participates_in CCO:P0003156 ! negative regulation of focal adhesion formation [Term] id: CCO:B0055447 name: NPY4R_HUMAN def: "Neuropeptide Y receptor type 4" [UniProtKB:P50391] synonym: "NPY4-R" EXACT [UniProtKB:P50391] synonym: "Pancreatic polypeptide receptor 1" EXACT [UniProtKB:P50391] synonym: "PP1" EXACT [UniProtKB:P50391] xref: EMBL:AAB07759.1 xref: EMBL:AAC50280.1 xref: EMBL:AAH96238.1 xref: EMBL:AAP23199.1 xref: EMBL:AAV68196.1 xref: EMBL:CAA91433.1 xref: UniProtKB:P50391 xref: UniProtKB:Q13456 xref: UniProtKB:Q5ISU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018844 ! PPYR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000156 ! peptide YY receptor activity relationship: has_function CCO:F0000157 ! pancreatic polypeptide receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055448 name: GDIB_HUMAN def: "Rab GDP dissociation inhibitor beta" [UniProtKB:P50395] synonym: "GDI-2" EXACT [UniProtKB:P50395] synonym: "Guanosine diphosphate dissociation inhibitor 2" EXACT [UniProtKB:P50395] synonym: "Rab GDI beta" EXACT [UniProtKB:P50395] xref: EMBL:AAD34588.1 xref: EMBL:AAH05145.1 xref: EMBL:AAP35514.1 xref: EMBL:BAA03095.1 xref: EMBL:CAA73734.1 xref: EMBL:CAA73735.1 xref: UniProtKB:O43928 xref: UniProtKB:P50395 xref: UniProtKB:Q9UQM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017909 ! GDI2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066436 ! GDIB_HUMAN-Phosphoserine61 relationship: transforms_into CCO:B0066437 ! GDIB_HUMAN-Phosphotyrosine203 [Term] id: CCO:B0055449 name: 5HT6R_HUMAN def: "5-hydroxytryptamine receptor 6" [UniProtKB:P50406] synonym: "5-HT-6" EXACT [UniProtKB:P50406] synonym: "Serotonin receptor 6" EXACT [UniProtKB:P50406] xref: EMBL:AAA92622.1 xref: EMBL:AAH74995.1 xref: EMBL:AAH74996.1 xref: EMBL:AAR07900.1 xref: EMBL:CAA88929.1 xref: EMBL:CAI19020.1 xref: EMBL:EAW94896.1 xref: UniProtKB:P50406 xref: UniProtKB:Q13640 xref: UniProtKB:Q5TGZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016858 ! HTR6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016008 ! fyn-htr6-4 physical interaction relationship: participates_in CCO:I0016213 ! fyn-htr6-7 physical interaction relationship: participates_in CCO:I0017799 ! fyn-htr6-3 direct interaction relationship: participates_in CCO:I0017973 ! fyn-htr6-2 physical interaction relationship: participates_in CCO:I0018722 ! fyn-htr6-5 physical interaction relationship: participates_in CCO:I0018723 ! fyn-htr6-6 physical interaction relationship: participates_in CCO:I0019211 ! fyn-htr6-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger relationship: transforms_into CCO:B0065227 ! 5HT6R_HUMAN-Phosphotyrosine125 [Term] id: CCO:B0055450 name: CPT1A_HUMAN def: "Carnitine O-palmitoyltransferase 1, liver isoform" [UniProtKB:P50416] synonym: "Carnitine O-palmitoyltransferase I, liver isoform" EXACT [UniProtKB:P50416] synonym: "Carnitine palmitoyltransferase 1A" EXACT [UniProtKB:P50416] synonym: "CPT I" EXACT [UniProtKB:P50416] synonym: "CPT1-L" EXACT [UniProtKB:P50416] synonym: "CPTI-L" EXACT [UniProtKB:P50416] synonym: "EC 2.3.1.21" EXACT [UniProtKB:P50416] xref: EMBL:AAC41748.1 xref: EMBL:AAH00185.1 xref: EMBL:AAP88793.1 xref: EMBL:CAD12625.1 xref: EMBL:CAD59673.1 xref: UniProtKB:P50416 xref: UniProtKB:Q8TCU0 xref: UniProtKB:Q9BWK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017442 ! CPT1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002956 ! regulation of insulin secretion relationship: transforms_into CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064453 ! CPT1A_HUMAN-Phosphothreonine588 relationship: transforms_into CCO:B0064454 ! CPT1A_HUMAN-Phosphothreonine604 relationship: transforms_into CCO:B0064455 ! CPT1A_HUMAN-Phosphoserine741 relationship: transforms_into CCO:B0064456 ! CPT1A_HUMAN-Phosphoserine747 [Term] id: CCO:B0055451 name: LHX2_HUMAN def: "LIM/homeobox protein Lhx2" [UniProtKB:P50458] synonym: "Homeobox protein LH-2" EXACT [UniProtKB:P50458] synonym: "LIM homeobox protein 2" EXACT [UniProtKB:P50458] xref: EMBL:AAB08752.1 xref: EMBL:AAD20013.1 xref: EMBL:AAH93662.1 xref: EMBL:AAI12186.1 xref: EMBL:BAC04371.1 xref: UniProtKB:O95860 xref: UniProtKB:P50458 xref: UniProtKB:Q52M57 xref: UniProtKB:Q8N1Z3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018486 ! LHX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055452 name: ETV1_HUMAN def: "ETS translocation variant 1" [UniProtKB:P50549] synonym: "Protein ER81" EXACT [UniProtKB:P50549] xref: EMBL:AAA79844.1 xref: EMBL:AAC62435.1 xref: EMBL:AAD29877.1 xref: EMBL:AAD29878.1 xref: EMBL:AAH98403.1 xref: EMBL:AAI06763.1 xref: EMBL:AAI06764.1 xref: EMBL:CAA60642.1 xref: UniProtKB:O75849 xref: UniProtKB:P50549 xref: UniProtKB:Q4KMQ6 xref: UniProtKB:Q9UQ71 xref: UniProtKB:Q9Y636 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017736 ! ETV1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055453 name: ASCL1_HUMAN def: "Achaete-scute homolog 1" [UniProtKB:P50553] synonym: "HASH1" EXACT [UniProtKB:P50553] xref: EMBL:AAA58376.1 xref: EMBL:AAH02341.1 xref: EMBL:AAH03134.1 xref: EMBL:AAH04425.1 xref: EMBL:AAH31299.1 xref: UniProtKB:P50553 xref: UniProtKB:Q9BQ30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017075 ! ASCL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017708 ! hash1-e2_2-2 direct interaction relationship: participates_in CCO:I0018092 ! hash1-e2_2-1 physical interaction relationship: participates_in CCO:I0018226 ! hash1-e2_2-3 physical interaction relationship: participates_in CCO:I0018227 ! e2_2-hash1-1 physical interaction relationship: participates_in CCO:I0018228 ! hash1-e47-1 physical interaction relationship: participates_in CCO:I0018229 ! e47-hash1-1 physical interaction relationship: participates_in CCO:I0018548 ! hash1-e2_2-4 physical interaction relationship: participates_in CCO:I0018549 ! hash1-e47-2 physical interaction relationship: participates_in CCO:I0018550 ! hash1-e2_2-5 physical interaction relationship: participates_in CCO:I0019297 ! ebox-hash1-e2_2-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0003269 ! regulation of timing of subpallium neuron differentiation [Term] id: CCO:B0055454 name: AP4A_HUMAN def: "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]" [UniProtKB:P50583] synonym: "Ap4A hydrolase" EXACT [UniProtKB:P50583] synonym: "Ap4Aase" EXACT [UniProtKB:P50583] synonym: "Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase" EXACT [UniProtKB:P50583] synonym: "Diadenosine tetraphosphatase" EXACT [UniProtKB:P50583] synonym: "EC 3.6.1.17" EXACT [UniProtKB:P50583] synonym: "Nucleoside diphosphate-linked moiety X motif 2" EXACT [UniProtKB:P50583] synonym: "Nudix motif 2" EXACT [UniProtKB:P50583] xref: EMBL:AAC50277.1 xref: EMBL:AAH04926.1 xref: EMBL:CAI15964.1 xref: EMBL:EAW58461.1 xref: UniProtKB:P50583 xref: UniProtKB:Q5T589 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016982 ! NUDT2_human relationship: has_function CCO:F0000556 ! bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity relationship: has_function CCO:F0002141 ! bis(5'-nucleosyl)-tetraphosphatase activity relationship: has_function CCO:F0002147 ! bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0065677 ! AP4A_HUMAN-N-acetylalanine2 [Term] id: CCO:B0055455 name: TNF10_HUMAN def: "Tumor necrosis factor ligand superfamily member 10" [UniProtKB:P50591] synonym: "Apo-2 ligand" EXACT [UniProtKB:P50591] synonym: "Apo-2L" EXACT [UniProtKB:P50591] synonym: "CD253 antigen" EXACT [UniProtKB:P50591] synonym: "Protein TRAIL" EXACT [UniProtKB:P50591] synonym: "TNF-related apoptosis-inducing ligand" EXACT [UniProtKB:P50591] xref: EMBL:AAB01233.1 xref: EMBL:AAC50332.1 xref: EMBL:AAH32722.1 xref: UniProtKB:P50591 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020297 ! TNFSF10_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015922 ! tnfsf10-tnfrs10b-1 physical interaction relationship: participates_in CCO:I0017360 ! tnfsf10-tnfrs10a-1 physical interaction relationship: participates_in CCO:I0017361 ! tnfsf10-tnfrs10a-3 physical interaction relationship: participates_in CCO:I0017362 ! tnfsf10-tnfrs10b-4 physical interaction relationship: participates_in CCO:I0017498 ! tnfsf10-tnfrs10a-2 physical interaction relationship: participates_in CCO:I0017813 ! tnfrsf10b-tnfsf10-1 direct interaction relationship: participates_in CCO:I0018609 ! tnfsf10-casp10-1 physical interaction relationship: participates_in CCO:I0019491 ! tnfsf10-casp10-2 physical interaction relationship: participates_in CCO:I0020203 ! tnfsf10-dkfzp564o052 physical interaction relationship: participates_in CCO:I0020484 ! tnfsf10-acp5 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055456 name: LU_HUMAN def: "Lutheran blood group glycoprotein precursor" [UniProtKB:P50895] synonym: "Auberger B antigen" EXACT [UniProtKB:P50895] synonym: "B-CAM cell surface glycoprotein" EXACT [UniProtKB:P50895] synonym: "CD239 antigen" EXACT [UniProtKB:P50895] synonym: "F8/G253 antigen" EXACT [UniProtKB:P50895] xref: EMBL:AAH50450.1 xref: EMBL:AAV88096.1 xref: EMBL:CAA56327.1 xref: EMBL:CAA58449.1 xref: UniProtKB:P50895 xref: UniProtKB:Q86VC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018531 ! BCAM_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055457 name: RAB7A_HUMAN def: "Ras-related protein Rab-7a" [UniProtKB:P51149] xref: EMBL:AAA86640.1 xref: EMBL:AAD02565.1 xref: EMBL:AAH08721.2 xref: EMBL:AAM21090.1 xref: EMBL:BAA91390.1 xref: EMBL:BAF83410.1 xref: EMBL:CAA63763.1 xref: EMBL:EAW79303.1 xref: UniProtKB:A8K3V6 xref: UniProtKB:P51149 xref: UniProtKB:Q9NWJ0 xref: UniProtKB:Q9UPB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019605 ! RAB7A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069694 ! RAB7A_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0069695 ! RAB7A_HUMAN-Phosphotyrosine183 relationship: transforms_into CCO:B0069696 ! RAB7A_HUMAN-Cysteine methyl ester207 [Term] id: CCO:B0055458 name: RAB9A_HUMAN def: "Ras-related protein Rab-9A" [UniProtKB:P51151] synonym: "Rab-9A" EXACT [UniProtKB:P51151] xref: EMBL:AAC51200.1 xref: EMBL:AAH17265.1 xref: EMBL:AAM21092.1 xref: EMBL:CAG29358.1 xref: UniProtKB:P51151 xref: UniProtKB:Q6ICN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019608 ! RAB9A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069698 ! RAB9A_HUMAN-Phosphoserine179 [Term] id: CCO:B0055459 name: RAB28_HUMAN def: "Ras-related protein Rab-28" [UniProtKB:P51157] synonym: "Rab-26" EXACT [UniProtKB:P51157] xref: EMBL:AAH35054.1 xref: EMBL:AAM21103.1 xref: EMBL:CAA64364.1 xref: UniProtKB:P51157 xref: UniProtKB:Q8IYR8 xref: UniProtKB:Q8NI05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019584 ! RAB28_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055460 name: PDE6C_HUMAN def: "Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'" [UniProtKB:P51160] synonym: "cGMP phosphodiesterase 6C" EXACT [UniProtKB:P51160] synonym: "EC 3.1.4.35" EXACT [UniProtKB:P51160] xref: EMBL:AAA92886.1 xref: EMBL:AAA96392.1 xref: EMBL:CAA64079.1 xref: EMBL:CAH72330.1 xref: EMBL:CAH73839.1 xref: EMBL:EAW50064.1 xref: UniProtKB:A6NCR6 xref: UniProtKB:P51160 xref: UniProtKB:Q5VY29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019345 ! PDE6C_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006858 ! 3',5'-cyclic-GMP phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055461 name: FABP6_HUMAN def: "Gastrotropin" [UniProtKB:P51161] synonym: "Fatty acid-binding protein 6" EXACT [UniProtKB:P51161] synonym: "GT" EXACT [UniProtKB:P51161] synonym: "I-15P" EXACT [UniProtKB:P51161] synonym: "I-BABP" EXACT [UniProtKB:P51161] synonym: "ILBP" EXACT [UniProtKB:P51161] synonym: "Ileal lipid-binding protein" EXACT [UniProtKB:P51161] synonym: "Intestinal 15 kDa protein" EXACT [UniProtKB:P51161] synonym: "Intestinal bile acid-binding protein" EXACT [UniProtKB:P51161] xref: EMBL:AAB82751.1 xref: EMBL:AAH22489.1 xref: EMBL:CAA62415.1 xref: EMBL:CAB65728.1 xref: UniProtKB:P51161 xref: UniProtKB:Q8TBI3 xref: UniProtKB:Q9UGI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017754 ! FABP6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0065190 ! FABP6_HUMAN-N-acetylalanine2 [Term] id: CCO:B0055462 name: PLCD1_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1" [UniProtKB:P51178] synonym: "EC 3.1.4.11" EXACT [UniProtKB:P51178] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:P51178] synonym: "Phospholipase C-delta-1" EXACT [UniProtKB:P51178] synonym: "PLC-delta-1" EXACT [UniProtKB:P51178] synonym: "PLC-III" EXACT [UniProtKB:P51178] xref: EMBL:AAA73567.1 xref: EMBL:AAH50382.2 xref: EMBL:EAW64507.1 xref: UniProtKB:P51178 xref: UniProtKB:Q86VN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019430 ! PLCD1_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055463 name: DAP1_HUMAN def: "Death-associated protein 1" [UniProtKB:P51397] synonym: "DAP-1" EXACT [UniProtKB:P51397] xref: EMBL:AAH02726.2 xref: EMBL:AAO89078.1 xref: EMBL:CAA53713.1 xref: UniProtKB:P51397 xref: UniProtKB:Q9BUC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017521 ! DAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020282 ! dap-setdb1 physical interaction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: transforms_into CCO:B0064625 ! DAP1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0064626 ! DAP1_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0064627 ! DAP1_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0064628 ! DAP1_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0064629 ! DAP1_HUMAN-Phosphoserine91 [Term] id: CCO:B0055464 name: RT29_HUMAN def: "28S ribosomal protein S29, mitochondrial" [UniProtKB:P51398] synonym: "DAP-3" EXACT [UniProtKB:P51398] synonym: "Death-associated protein 3" EXACT [UniProtKB:P51398] synonym: "Ionizing radiation resistance conferring protein" EXACT [UniProtKB:P51398] synonym: "MRP-S29" EXACT [UniProtKB:P51398] synonym: "S29mt" EXACT [UniProtKB:P51398] xref: EMBL:AAA57443.1 xref: EMBL:BAB54960.1 xref: EMBL:CAA58535.1 xref: EMBL:CAH71647.1 xref: UniProtKB:P51398 xref: UniProtKB:Q13044 xref: UniProtKB:Q96Q20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019808 ! DAP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000344 ! mitochondrial ribosome relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0016517 ! ikbkg-dap3 physical interaction relationship: participates_in CCO:I0016798 ! nfkb2-dap3 physical interaction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: transforms_into CCO:B0070252 ! RT29_HUMAN-Phosphothreonine93 relationship: transforms_into CCO:B0070253 ! RT29_HUMAN-Phosphothreonine272 [Term] id: CCO:B0055465 name: RORG_HUMAN def: "Nuclear receptor ROR-gamma" [UniProtKB:P51449] synonym: "Nuclear receptor RZR-gamma" EXACT [UniProtKB:P51449] synonym: "Nuclear receptor subfamily 1 group F member 3" EXACT [UniProtKB:P51449] synonym: "Retinoid-related orphan receptor-gamma" EXACT [UniProtKB:P51449] xref: EMBL:AAA64751.1 xref: EMBL:AAH31554.1 xref: EMBL:CAD38900.1 xref: UniProtKB:P51449 xref: UniProtKB:Q8N5V7 xref: UniProtKB:Q8NCY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019773 ! RORC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055466 name: ZNF80_HUMAN def: "Zinc finger protein 80" [UniProtKB:P51504] synonym: "ZNFPT17" EXACT [UniProtKB:P51504] xref: EMBL:AAH69606.2 xref: EMBL:AAH69826.2 xref: EMBL:AAI29926.1 xref: EMBL:CAA46340.1 xref: EMBL:EAW79603.1 xref: UniProtKB:P51504 xref: UniProtKB:Q6NSW4 xref: UniProtKB:Q6NT14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020988 ! ZNF80_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055467 name: ZNF84_HUMAN def: "Zinc finger protein 84" [UniProtKB:P51523] synonym: "Zinc finger protein HPF2" EXACT [UniProtKB:P51523] xref: EMBL:AAA79359.1 xref: EMBL:AAH36656.1 xref: EMBL:AAH48350.2 xref: EMBL:AAH62552.1 xref: EMBL:CAB94232.2 xref: UniProtKB:P51523 xref: UniProtKB:Q3ZCV9 xref: UniProtKB:Q5D057 xref: UniProtKB:Q86XU8 xref: UniProtKB:Q9NNX7 xref: UniProtKB:Q9UC17 xref: UniProtKB:Q9UC18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020990 ! ZNF84_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055468 name: P2RX1_HUMAN def: "P2X purinoceptor 1" [UniProtKB:P51575] synonym: "ATP receptor" EXACT [UniProtKB:P51575] synonym: "P2X1" EXACT [UniProtKB:P51575] synonym: "Purinergic receptor" EXACT [UniProtKB:P51575] xref: EMBL:AAC24494.1 xref: EMBL:AAC50698.1 xref: EMBL:AAD55395.1 xref: EMBL:AAH44657.1 xref: EMBL:CAA58657.1 xref: UniProtKB:P51575 xref: UniProtKB:Q9UK84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019258 ! P2RX1_human relationship: has_function CCO:F0000165 ! purinergic nucleotide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001273 ! ATP-gated cation channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001524 ! cation channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055469 name: P2RY4_HUMAN def: "P2Y purinoceptor 4" [UniProtKB:P51582] synonym: "P2P" EXACT [UniProtKB:P51582] synonym: "P2Y4" EXACT [UniProtKB:P51582] synonym: "UNR" EXACT [UniProtKB:P51582] synonym: "Uridine nucleotide receptor" EXACT [UniProtKB:P51582] xref: EMBL:AAC50347.1 xref: EMBL:AAH95503.1 xref: EMBL:AAH96067.1 xref: EMBL:AAH96068.1 xref: EMBL:AAH96069.1 xref: EMBL:AAH96070.1 xref: EMBL:CAA62963.1 xref: EMBL:CAA65415.1 xref: EMBL:CAI41492.1 xref: UniProtKB:P51582 xref: UniProtKB:Q4VBB7 xref: UniProtKB:Q4VBB8 xref: UniProtKB:Q502W2 xref: UniProtKB:Q5JT22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019267 ! P2RY4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: transforms_into CCO:B0069019 ! P2RY4_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0069020 ! P2RY4_HUMAN-Phosphoserine334 [Term] id: CCO:B0055470 name: MECP2_HUMAN def: "Methyl-CpG-binding protein 2" [UniProtKB:P51608] synonym: "MeCP-2 protein" EXACT [UniProtKB:P51608] synonym: "MeCP2" EXACT [UniProtKB:P51608] xref: EMBL:AAC08757.1 xref: EMBL:AAC32737.1 xref: EMBL:AAF33023.1 xref: EMBL:AAH11612.1 xref: EMBL:AAS55455.1 xref: EMBL:CAA61599.1 xref: EMBL:CAA64331.1 xref: EMBL:CAA68001.1 xref: EMBL:CAA73190.1 xref: EMBL:CAB46446.1 xref: EMBL:CAD97991.1 xref: UniProtKB:O15233 xref: UniProtKB:P51608 xref: UniProtKB:Q6QHH9 xref: UniProtKB:Q7Z384 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018596 ! MECP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015881 ! brm-mecp2-4 physical interaction relationship: participates_in CCO:I0015882 ! brm-mecp2-5 physical interaction relationship: participates_in CCO:I0017490 ! brm-mecp2-2 physical interaction relationship: participates_in CCO:I0017491 ! brm-mecp2-3 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068112 ! MECP2_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0068113 ! MECP2_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0068114 ! MECP2_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0068115 ! MECP2_HUMAN-Phosphoserine423 relationship: transforms_into CCO:B0068116 ! MECP2_HUMAN-Phosphoserine426 [Term] id: CCO:B0055471 name: IRAK1_HUMAN def: "Interleukin-1 receptor-associated kinase 1" [UniProtKB:P51617] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P51617] synonym: "IRAK-1" EXACT [UniProtKB:P51617] xref: EMBL:AAC08756.1 xref: EMBL:AAC41949.1 xref: EMBL:AAH54000.1 xref: EMBL:AAK62888.1 xref: UniProtKB:P51617 xref: UniProtKB:Q7Z5V4 xref: UniProtKB:Q96RL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018308 ! IRAK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015926 ! irak-traf6 physical interaction relationship: participates_in CCO:I0016931 ! map3k7ip1-irak1 physical interaction relationship: participates_in CCO:I0017500 ! irak-traf6-1 physical interaction relationship: participates_in CCO:I0017857 ! peli1-irak1-1 physical interaction relationship: participates_in CCO:I0017990 ! irak1-myd88-ex1 physical interaction relationship: participates_in CCO:I0017993 ! irak1-traf6-ex1 physical interaction relationship: participates_in CCO:I0017995 ! irak1-irak1-ex1 physical interaction relationship: participates_in CCO:I0017998 ! irak1-irak2-ex1 physical interaction relationship: participates_in CCO:I0017999 ! irak1-irak3-ex1 physical interaction relationship: participates_in CCO:I0018000 ! irak2-irak1-ex1 physical interaction relationship: participates_in CCO:I0018002 ! irak3-irak1-ex1 physical interaction relationship: participates_in CCO:I0018034 ! pellino-irak-irak4 physical interaction relationship: participates_in CCO:I0018147 ! irak1-peli2-3 physical interaction relationship: participates_in CCO:I0018773 ! irak1-peli2-2 physical interaction relationship: participates_in CCO:I0019233 ! irak4-peli2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0067152 ! IRAK1_HUMAN-Phosphoserine568 [Term] id: CCO:B0055472 name: CCR3_HUMAN def: "C-C chemokine receptor type 3" [UniProtKB:P51677] synonym: "C-C CKR-3" EXACT [UniProtKB:P51677] synonym: "CC-CKR-3" EXACT [UniProtKB:P51677] synonym: "CCR-3" EXACT [UniProtKB:P51677] synonym: "CCR3" EXACT [UniProtKB:P51677] synonym: "CD193 antigen" EXACT [UniProtKB:P51677] synonym: "CKR3" EXACT [UniProtKB:P51677] synonym: "Eosinophil eotaxin receptor" EXACT [UniProtKB:P51677] xref: EMBL:AAB09726.1 xref: EMBL:AAB16831.1 xref: EMBL:AAB82589.1 xref: EMBL:AAC50469.1 xref: EMBL:AAI10298.1 xref: EMBL:AAI30319.1 xref: EMBL:AAI30321.1 xref: EMBL:AAL85154.1 xref: EMBL:AAO65970.2 xref: EMBL:ABK41943.1 xref: EMBL:BAA86964.1 xref: UniProtKB:P51677 xref: UniProtKB:Q15748 xref: UniProtKB:Q2YDB9 xref: UniProtKB:Q86WD2 xref: UniProtKB:Q9ULY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017278 ! CCR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:B0055473 name: CCR4_HUMAN def: "C-C chemokine receptor type 4" [UniProtKB:P51679] synonym: "C-C CKR-4" EXACT [UniProtKB:P51679] synonym: "CC-CKR-4" EXACT [UniProtKB:P51679] synonym: "CCR-4" EXACT [UniProtKB:P51679] synonym: "CCR4" EXACT [UniProtKB:P51679] synonym: "CD194 antigen" EXACT [UniProtKB:P51679] synonym: "K5-5" EXACT [UniProtKB:P51679] xref: EMBL:AAH69139.1 xref: EMBL:AAH71751.1 xref: EMBL:AAH74935.1 xref: EMBL:AAP84352.1 xref: EMBL:BAA86965.1 xref: EMBL:BAA86966.1 xref: EMBL:BAA86967.1 xref: EMBL:BAA86968.1 xref: EMBL:BAA86969.1 xref: EMBL:CAA59743.1 xref: UniProtKB:P51679 xref: UniProtKB:Q9ULY6 xref: UniProtKB:Q9ULY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017279 ! CCR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055474 name: CCR5_HUMAN def: "C-C chemokine receptor type 5" [UniProtKB:P51681] synonym: "C-C CKR-5" EXACT [UniProtKB:P51681] synonym: "CC-CKR-5" EXACT [UniProtKB:P51681] synonym: "CCR-5" EXACT [UniProtKB:P51681] synonym: "CCR5" EXACT [UniProtKB:P51681] synonym: "CD195 antigen" EXACT [UniProtKB:P51681] synonym: "CHEMR13" EXACT [UniProtKB:P51681] synonym: "HIV-1 fusion coreceptor" EXACT [UniProtKB:P51681] xref: EMBL:AAB17071.1 xref: EMBL:AAB57793.1 xref: EMBL:AAB65700.1 xref: EMBL:AAB65701.1 xref: EMBL:AAB65702.1 xref: EMBL:AAB65703.1 xref: EMBL:AAB65705.1 xref: EMBL:AAB65706.1 xref: EMBL:AAB65707.1 xref: EMBL:AAB65708.1 xref: EMBL:AAB65709.1 xref: EMBL:AAB65710.1 xref: EMBL:AAB65711.1 xref: EMBL:AAB65712.1 xref: EMBL:AAB65713.1 xref: EMBL:AAB65714.1 xref: EMBL:AAB65715.1 xref: EMBL:AAB65716.1 xref: EMBL:AAB65717.1 xref: EMBL:AAB65718.1 xref: EMBL:AAB65719.1 xref: EMBL:AAB65720.1 xref: EMBL:AAB65721.1 xref: EMBL:AAB65722.1 xref: EMBL:AAB65723.1 xref: EMBL:AAB65724.1 xref: EMBL:AAB65725.1 xref: EMBL:AAB65726.1 xref: EMBL:AAB65727.1 xref: EMBL:AAB65728.1 xref: EMBL:AAB65729.1 xref: EMBL:AAB65730.1 xref: EMBL:AAB65731.1 xref: EMBL:AAB65732.1 xref: EMBL:AAB65733.1 xref: EMBL:AAB65734.1 xref: EMBL:AAB65735.1 xref: EMBL:AAB65736.1 xref: EMBL:AAB65737.1 xref: EMBL:AAB94735.1 xref: EMBL:AAC50598.1 xref: EMBL:AAC51797.1 xref: EMBL:AAD18131.1 xref: EMBL:AAH38398.1 xref: EMBL:AAO65971.1 xref: EMBL:CAA62796.1 xref: UniProtKB:O14692 xref: UniProtKB:O14693 xref: UniProtKB:O14695 xref: UniProtKB:O14696 xref: UniProtKB:O14697 xref: UniProtKB:O14698 xref: UniProtKB:O14699 xref: UniProtKB:O14700 xref: UniProtKB:O14701 xref: UniProtKB:O14702 xref: UniProtKB:O14703 xref: UniProtKB:O14704 xref: UniProtKB:O14705 xref: UniProtKB:O14706 xref: UniProtKB:O14707 xref: UniProtKB:O14708 xref: UniProtKB:O15538 xref: UniProtKB:P51681 xref: UniProtKB:Q9UPA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017280 ! CCR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015909 ! ccr5-cxcr4-1 colocalization relationship: participates_in CCO:I0017796 ! ccr5-myh9-1 physical interaction relationship: participates_in CCO:I0018486 ! ccr5-cxcr4-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0064124 ! CCR5_HUMAN-Sulfotyrosine3 relationship: transforms_into CCO:B0064125 ! CCR5_HUMAN-Sulfotyrosine10 relationship: transforms_into CCO:B0064126 ! CCR5_HUMAN-Sulfotyrosine14 relationship: transforms_into CCO:B0064127 ! CCR5_HUMAN-Sulfotyrosine15 relationship: transforms_into CCO:B0064128 ! CCR5_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0064129 ! CCR5_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0064130 ! CCR5_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0064131 ! CCR5_HUMAN-Phosphoserine349 [Term] id: CCO:B0055475 name: CCR6_HUMAN def: "C-C chemokine receptor type 6" [UniProtKB:P51684] synonym: "C-C CKR-6" EXACT [UniProtKB:P51684] synonym: "CC-CKR-6" EXACT [UniProtKB:P51684] synonym: "CCR-6" EXACT [UniProtKB:P51684] synonym: "CD196 antigen" EXACT [UniProtKB:P51684] synonym: "Chemokine receptor-like 3" EXACT [UniProtKB:P51684] synonym: "CKR-L3" EXACT [UniProtKB:P51684] synonym: "DRY6" EXACT [UniProtKB:P51684] synonym: "G-protein coupled receptor 29" EXACT [UniProtKB:P51684] synonym: "GPR-CY4" EXACT [UniProtKB:P51684] synonym: "GPRCY4" EXACT [UniProtKB:P51684] synonym: "LARC receptor" EXACT [UniProtKB:P51684] xref: EMBL:AAB06949.1 xref: EMBL:AAB62714.1 xref: EMBL:AAC51124.1 xref: EMBL:AAC51125.1 xref: EMBL:AAH37960.1 xref: EMBL:AAO92293.1 xref: EMBL:CAB02144.1 xref: EMBL:CAB99328.1 xref: UniProtKB:P51684 xref: UniProtKB:P78553 xref: UniProtKB:Q92846 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017281 ! CCR6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055476 name: CCR8_HUMAN def: "C-C chemokine receptor type 8" [UniProtKB:P51685] synonym: "C-C CKR-8" EXACT [UniProtKB:P51685] synonym: "CC-chemokine receptor CHEMR1" EXACT [UniProtKB:P51685] synonym: "CC-CKR-8" EXACT [UniProtKB:P51685] synonym: "CCR-8" EXACT [UniProtKB:P51685] synonym: "CDw198 antigen" EXACT [UniProtKB:P51685] synonym: "Chemokine receptor-like 1" EXACT [UniProtKB:P51685] synonym: "CKR-L1" EXACT [UniProtKB:P51685] synonym: "CMKBRL2" EXACT [UniProtKB:P51685] synonym: "GPR-CY6" EXACT [UniProtKB:P51685] synonym: "GPRCY6" EXACT [UniProtKB:P51685] synonym: "TER1" EXACT [UniProtKB:P51685] xref: EMBL:AAB05542.1 xref: EMBL:AAB61962.1 xref: EMBL:AAB62547.1 xref: EMBL:AAH69067.1 xref: EMBL:AAH74743.1 xref: EMBL:AAI07160.1 xref: EMBL:BAA23387.1 xref: EMBL:CAA69712.1 xref: EMBL:CAB02142.1 xref: UniProtKB:P51685 xref: UniProtKB:Q3KNQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017283 ! CCR8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055477 name: CCR9_HUMAN def: "C-C chemokine receptor type 9" [UniProtKB:P51686] synonym: "C-C CKR-9" EXACT [UniProtKB:P51686] synonym: "CC-CKR-9" EXACT [UniProtKB:P51686] synonym: "CCR-9" EXACT [UniProtKB:P51686] synonym: "CDw199 antigen" EXACT [UniProtKB:P51686] synonym: "G-protein coupled receptor 28" EXACT [UniProtKB:P51686] synonym: "GPR-9-6" EXACT [UniProtKB:P51686] xref: EMBL:AAA93319.1 xref: EMBL:AAF66699.1 xref: EMBL:AAF66700.1 xref: EMBL:AAH69678.1 xref: EMBL:AAH95516.1 xref: EMBL:AAO92294.1 xref: EMBL:CAB43477.1 xref: UniProtKB:P51686 xref: UniProtKB:Q4VBM3 xref: UniProtKB:Q549E0 xref: UniProtKB:Q9UQQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017284 ! CCR9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055478 name: ZN157_HUMAN def: "Zinc finger protein 157" [UniProtKB:P51786] synonym: "HZF22" EXACT [UniProtKB:P51786] synonym: "Zinc finger protein 22" EXACT [UniProtKB:P51786] xref: EMBL:AAA97578.1 xref: EMBL:AAH75003.1 xref: EMBL:CAC88160.2 xref: EMBL:CAI41199.1 xref: UniProtKB:P51786 xref: UniProtKB:Q96LE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020634 ! ZNF157_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055479 name: CLCN6_HUMAN def: "Chloride channel protein 6" [UniProtKB:P51797] synonym: "ClC-6" EXACT [UniProtKB:P51797] xref: EMBL:AAB69287.1 xref: EMBL:AAI17421.1 xref: EMBL:AAI17425.1 xref: EMBL:BAA05836.4 xref: EMBL:CAA58292.1 xref: EMBL:CAA65255.1 xref: EMBL:CAA67835.1 xref: EMBL:CAA67836.1 xref: EMBL:CAA67837.1 xref: EMBL:CAA67838.1 xref: EMBL:CAI15891.1 xref: EMBL:CAI15892.1 xref: EMBL:CAI15893.1 xref: EMBL:CAI15894.1 xref: EMBL:CAI15895.1 xref: EMBL:CAI23402.1 xref: EMBL:CAI23403.1 xref: EMBL:CAI23404.1 xref: EMBL:CAI23405.1 xref: EMBL:CAI23406.1 xref: UniProtKB:O60818 xref: UniProtKB:O60819 xref: UniProtKB:O60820 xref: UniProtKB:O60821 xref: UniProtKB:P51797 xref: UniProtKB:P78520 xref: UniProtKB:P78521 xref: UniProtKB:Q17R81 xref: UniProtKB:Q5SNW2 xref: UniProtKB:Q5SNW3 xref: UniProtKB:Q5SNX1 xref: UniProtKB:Q5SNX2 xref: UniProtKB:Q5SNX3 xref: UniProtKB:Q99427 xref: UniProtKB:Q99428 xref: UniProtKB:Q99429 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017383 ! CLCN6_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001515 ! voltage-gated chloride channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055480 name: PLXA3_HUMAN def: "Plexin-A3 precursor" [UniProtKB:P51805] synonym: "Plexin-4" EXACT [UniProtKB:P51805] synonym: "Semaphorin receptor SEX" EXACT [UniProtKB:P51805] xref: EMBL:CAA61132.1 xref: EMBL:CAI43194.1 xref: UniProtKB:P51805 xref: UniProtKB:Q5HY36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019448 ! PLXNA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002903 ! negative regulation of axon extension involved in axon guidance relationship: transforms_into CCO:B0069424 ! PLXA3_HUMAN-Phosphoserine1607 relationship: transforms_into CCO:B0069425 ! PLXA3_HUMAN-Phosphoserine1610 [Term] id: CCO:B0055481 name: ZNF41_HUMAN def: "Zinc finger protein 41" [UniProtKB:P51814] xref: EMBL:AAA61312.1 xref: EMBL:AAH15023.1 xref: EMBL:CAB51740.1 xref: EMBL:CAB53035.1 xref: EMBL:CAB53036.1 xref: EMBL:CAB53037.1 xref: EMBL:CAB53038.1 xref: EMBL:CAB53039.1 xref: EMBL:CAB53040.1 xref: EMBL:CAB53041.1 xref: EMBL:CAI41591.1 xref: EMBL:CAI41627.1 xref: UniProtKB:P51814 xref: UniProtKB:Q96LE8 xref: UniProtKB:Q9UMC4 xref: UniProtKB:Q9UMV5 xref: UniProtKB:Q9UMV6 xref: UniProtKB:Q9UMV7 xref: UniProtKB:Q9UMV8 xref: UniProtKB:Q9UMV9 xref: UniProtKB:Q9UMW0 xref: UniProtKB:Q9UMW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020974 ! ZNF41_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055482 name: AFF3_HUMAN def: "AF4/FMR2 family member 3" [UniProtKB:P51826] synonym: "Lymphoid nuclear protein related to AF4" EXACT [UniProtKB:P51826] synonym: "Protein LAF-4" EXACT [UniProtKB:P51826] xref: EMBL:AAA98763.1 xref: EMBL:AAH36895.1 xref: EMBL:AAY14792.1 xref: EMBL:AAY24187.1 xref: EMBL:AAY24278.1 xref: EMBL:AAY24315.1 xref: EMBL:BAD92871.1 xref: UniProtKB:P51826 xref: UniProtKB:Q53RD6 xref: UniProtKB:Q53S47 xref: UniProtKB:Q53SI6 xref: UniProtKB:Q53TB9 xref: UniProtKB:Q59F27 xref: UniProtKB:Q8IWJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016928 ! AFF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065471 ! AFF3_HUMAN-Phosphothreonine310 relationship: transforms_into CCO:B0065472 ! AFF3_HUMAN-Phosphoserine316 [Term] id: CCO:B0055483 name: NR0B1_HUMAN def: "Nuclear receptor subfamily 0 group B member 1" [UniProtKB:P51843] synonym: "DSS-AHC critical region on the X chromosome protein 1" EXACT [UniProtKB:P51843] synonym: "Nuclear receptor DAX-1" EXACT [UniProtKB:P51843] xref: EMBL:AAB32751.1 xref: EMBL:AAC13875.1 xref: EMBL:AAH11564.1 xref: UniProtKB:P51843 xref: UniProtKB:Q96F69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018847 ! NR0B1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003603 ! negative regulator of basal transcription activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0004995 ! DNA hairpin binding relationship: has_function CCO:F0005586 ! steroid hormone receptor binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001701 ! polysomal ribosome relationship: participates_in CCO:I0016176 ! nr0b1-rora physical interaction relationship: participates_in CCO:I0017584 ! nr0b1-rora-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001800 ! negative regulation of steroid hormone receptor signaling pathway relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0055484 name: HDGF_HUMAN def: "Hepatoma-derived growth factor" [UniProtKB:P51858] synonym: "HDGF" EXACT [UniProtKB:P51858] synonym: "High-mobility group protein 1-like 2" EXACT [UniProtKB:P51858] synonym: "HMG-1L2" EXACT [UniProtKB:P51858] xref: EMBL:AAH18991.1 xref: EMBL:BAA03903.1 xref: EMBL:CAI16347.1 xref: UniProtKB:P51858 xref: UniProtKB:Q5SZ09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018110 ! HDGF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0066780 ! HDGF_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0066781 ! HDGF_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0066782 ! HDGF_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0066783 ! HDGF_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0066784 ! HDGF_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0066785 ! HDGF_HUMAN-Phosphothreonine200 relationship: transforms_into CCO:B0066786 ! HDGF_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0066787 ! HDGF_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0066788 ! HDGF_HUMAN-Phosphoserine239 [Term] id: CCO:B0055485 name: DGKE_HUMAN def: "Diacylglycerol kinase epsilon" [UniProtKB:P52429] synonym: "DAG kinase epsilon" EXACT [UniProtKB:P52429] synonym: "DGK-epsilon" EXACT [UniProtKB:P52429] synonym: "Diglyceride kinase epsilon" EXACT [UniProtKB:P52429] synonym: "EC 2.7.1.107" EXACT [UniProtKB:P52429] xref: EMBL:AAC50497.1 xref: EMBL:AAD45666.1 xref: UniProtKB:P52429 xref: UniProtKB:Q9UKQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017567 ! DGKE_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055486 name: GDIR2_HUMAN def: "Rho GDP-dissociation inhibitor 2" [UniProtKB:P52566] synonym: "Ly-GDI" EXACT [UniProtKB:P52566] synonym: "Rho GDI 2" EXACT [UniProtKB:P52566] synonym: "Rho-GDI beta" EXACT [UniProtKB:P52566] xref: EMBL:AAA59539.1 xref: EMBL:AAH09200.1 xref: EMBL:AAM21075.1 xref: EMBL:CAA49280.1 xref: UniProtKB:P52566 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017910 ! ARHGDIB_human relationship: has_function CCO:F0001399 ! Rho GDP-dissociation inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0066438 ! GDIR2_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0066439 ! GDIR2_HUMAN-Phosphotyrosine24 [Term] id: CCO:B0055487 name: NUPL_HUMAN def: "Nucleoporin-like protein RIP" [UniProtKB:P52594] synonym: "HIV-1 Rev-binding protein" EXACT [UniProtKB:P52594] synonym: "Rev-interacting protein" EXACT [UniProtKB:P52594] synonym: "Rev/Rex activation domain-binding protein" EXACT [UniProtKB:P52594] xref: EMBL:AAC37580.1 xref: EMBL:AAH30592.1 xref: EMBL:AAH96272.1 xref: EMBL:AAH96273.1 xref: EMBL:AAH96274.1 xref: EMBL:AAH96275.1 xref: EMBL:AAX93270.1 xref: EMBL:AAY24254.1 xref: EMBL:CAA61667.1 xref: UniProtKB:P52594 xref: UniProtKB:Q15277 xref: UniProtKB:Q4VAS0 xref: UniProtKB:Q4VAS1 xref: UniProtKB:Q4VAS3 xref: UniProtKB:Q53QT8 xref: UniProtKB:Q53R11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018891 ! HRB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0016337 ! eps15-hrb-1 physical interaction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0068944 ! NUPL_HUMAN-Phosphothreonine177 relationship: transforms_into CCO:B0068945 ! NUPL_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0068946 ! NUPL_HUMAN-Phosphoserine181 [Term] id: CCO:B0055488 name: TF2AA_HUMAN def: "Transcription initiation factor IIA subunit 1" [UniProtKB:P52655] synonym: "General transcription factor IIA subunit 1" EXACT [UniProtKB:P52655] synonym: "TFIIA-42" EXACT [UniProtKB:P52655] synonym: "TFIIAL" EXACT [UniProtKB:P52655] xref: EMBL:AAF26776.1 xref: EMBL:AAI07156.1 xref: EMBL:AAI07157.1 xref: EMBL:BAA03603.1 xref: EMBL:BAA03604.1 xref: EMBL:CAA53151.1 xref: EMBL:CAA53152.1 xref: EMBL:CAA54442.1 xref: UniProtKB:P52655 xref: UniProtKB:Q3KNQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020236 ! GTF2A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018140 ! gtf2a1-tbp-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071357 ! TF2AA_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0071358 ! TF2AA_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0071359 ! TF2AA_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0071360 ! TF2AA_HUMAN-Phosphoserine321 [Term] id: CCO:B0055489 name: VAV2_HUMAN def: "Guanine nucleotide exchange factor VAV2" [UniProtKB:P52735] synonym: "VAV-2" EXACT [UniProtKB:P52735] xref: EMBL:AAB34377.1 xref: EMBL:AAH33187.1 xref: EMBL:AAI32966.1 xref: EMBL:AAI32968.1 xref: EMBL:AAS75591.1 xref: EMBL:CAE45861.1 xref: EMBL:CAI12278.1 xref: EMBL:CAI12279.1 xref: EMBL:CAI12280.1 xref: EMBL:CAI13722.1 xref: EMBL:CAI13723.1 xref: EMBL:CAI13724.1 xref: EMBL:CAI15781.1 xref: EMBL:CAI15782.1 xref: EMBL:CAI15783.1 xref: EMBL:EAW88108.1 xref: UniProtKB:A2RUM4 xref: UniProtKB:A8MQ12 xref: UniProtKB:P52735 xref: UniProtKB:Q5SYV3 xref: UniProtKB:Q5SYV4 xref: UniProtKB:Q5SYV5 xref: UniProtKB:Q6N012 xref: UniProtKB:Q6PIJ9 xref: UniProtKB:Q6Q317 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020434 ! VAV2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0018005 ! nek3-vav2-2 physical interaction relationship: participates_in CCO:I0018779 ! nek3-vav2-3 physical interaction relationship: participates_in CCO:I0018780 ! vav2-prlr-1 physical interaction relationship: participates_in CCO:I0018781 ! nek3-vav2-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0071787 ! VAV2_HUMAN-Phosphotyrosine142 relationship: transforms_into CCO:B0071788 ! VAV2_HUMAN-Phosphotyrosine159 relationship: transforms_into CCO:B0071789 ! VAV2_HUMAN-Phosphotyrosine172 [Term] id: CCO:B0055490 name: ZN133_HUMAN def: "Zinc finger protein 133" [UniProtKB:P52736] synonym: "Zinc finger protein 150" EXACT [UniProtKB:P52736] xref: EMBL:AAC50260.1 xref: EMBL:AAH01887.1 xref: EMBL:CAC15508.1 xref: UniProtKB:P52736 xref: UniProtKB:Q9BUV2 xref: UniProtKB:Q9H443 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020623 ! ZNF133_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055491 name: ZN136_HUMAN def: "Zinc finger protein 136" [UniProtKB:P52737] xref: EMBL:AAC50261.1 xref: EMBL:AAH06421.1 xref: UniProtKB:P52737 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020625 ! ZNF136_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015472 ! mdfi-znf136 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055492 name: ZN140_HUMAN def: "Zinc finger protein 140" [UniProtKB:P52738] xref: EMBL:AAC50262.1 xref: EMBL:AAH40561.1 xref: EMBL:BAG53698.1 xref: EMBL:EAW54795.1 xref: UniProtKB:P52738 xref: UniProtKB:Q8IV75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020628 ! ZNF140_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055493 name: ZN131_HUMAN def: "Zinc finger protein 131" [UniProtKB:P52739] xref: EMBL:AAC50251.1 xref: EMBL:AAH35875.1 xref: UniProtKB:P52739 xref: UniProtKB:Q6PIF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020621 ! ZNF131_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055494 name: ZN132_HUMAN def: "Zinc finger protein 132" [UniProtKB:P52740] xref: EMBL:AAC50252.1 xref: EMBL:AAI09108.1 xref: EMBL:AAI09109.1 xref: EMBL:EAW72591.1 xref: UniProtKB:P52740 xref: UniProtKB:Q32MI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020622 ! ZNF132_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055495 name: ZN135_HUMAN def: "Zinc finger protein 135" [UniProtKB:P52742] synonym: "Zinc finger protein 61" EXACT [UniProtKB:P52742] synonym: "Zinc finger protein 78-like 1" EXACT [UniProtKB:P52742] xref: EMBL:AAC50254.1 xref: EMBL:AAH46434.1 xref: UniProtKB:P52742 xref: UniProtKB:Q5U5L3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020624 ! ZNF135_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055496 name: ZN137_HUMAN def: "Zinc finger protein 137" [UniProtKB:P52743] xref: EMBL:AAC50255.1 xref: EMBL:AAI10457.1 xref: UniProtKB:P52743 xref: UniProtKB:Q2TBC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020626 ! ZNF137_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055497 name: ZN138_HUMAN def: "Zinc finger protein 138" [UniProtKB:P52744] xref: EMBL:AAC50263.1 xref: UniProtKB:P52744 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020627 ! ZNF138_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055498 name: ZN142_HUMAN def: "Zinc finger protein 142" [UniProtKB:P52746] synonym: "HA4654" EXACT [UniProtKB:P52746] xref: EMBL:AAC50265.1 xref: EMBL:BAA13242.2 xref: UniProtKB:P52746 xref: UniProtKB:Q92510 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020630 ! ZNF142_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072049 ! ZN142_HUMAN-Phosphoserine1319 [Term] id: CCO:B0055499 name: ZN143_HUMAN def: "Zinc finger protein 143" [UniProtKB:P52747] synonym: "SPH-binding factor" EXACT [UniProtKB:P52747] xref: EMBL:AAC50266.1 xref: EMBL:AAC96102.1 xref: EMBL:AAH20219.1 xref: UniProtKB:O75559 xref: UniProtKB:P52747 xref: UniProtKB:Q8WUK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020631 ! ZNF143_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0000297 ! RNA polymerase III transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter [Term] id: CCO:B0055500 name: CHIO_HUMAN def: "Beta-chimaerin" [UniProtKB:P52757] synonym: "Beta-chimerin" EXACT [UniProtKB:P52757] synonym: "Rho GTPase-activating protein 3" EXACT [UniProtKB:P52757] xref: EMBL:AAA16836.1 xref: EMBL:AAA19191.1 xref: EMBL:AAA86528.1 xref: EMBL:AAC06177.1 xref: EMBL:AAI12156.1 xref: EMBL:AAS07498.1 xref: UniProtKB:P52757 xref: UniProtKB:Q2M203 xref: UniProtKB:Q75MM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017355 ! CHN2_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0019947 ! chn2-bat3 physical interaction relationship: participates_in CCO:I0019948 ! chn2-sumo2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055501 name: RM12_HUMAN def: "39S ribosomal protein L12, mitochondrial precursor" [UniProtKB:P52815] synonym: "5c5-2" EXACT [UniProtKB:P52815] synonym: "L12mt" EXACT [UniProtKB:P52815] synonym: "MRP-L12" EXACT [UniProtKB:P52815] xref: EMBL:AAD16894.1 xref: EMBL:AAG32154.1 xref: EMBL:AAH02344.1 xref: EMBL:AAH07497.1 xref: EMBL:CAA56249.1 xref: UniProtKB:P52815 xref: UniProtKB:Q969U0 xref: UniProtKB:Q9HCA2 xref: UniProtKB:Q9UQJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019753 ! MRPL12_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000345 ! mitochondrial large ribosomal subunit relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0019767 ! mrpl12-mrpl12 physical interaction relationship: participates_in CCO:I0020603 ! mrpl12-tmem51 physical interaction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0055502 name: STC1_HUMAN def: "Stanniocalcin-1 precursor" [UniProtKB:P52823] synonym: "STC-1" EXACT [UniProtKB:P52823] xref: EMBL:AAA88903.1 xref: EMBL:AAC09472.1 xref: EMBL:AAH29044.1 xref: EMBL:AAL79522.1 xref: UniProtKB:P52823 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020067 ! STC1_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0055503 name: DGKQ_HUMAN def: "Diacylglycerol kinase theta" [UniProtKB:P52824] synonym: "DAG kinase theta" EXACT [UniProtKB:P52824] synonym: "DGK-theta" EXACT [UniProtKB:P52824] synonym: "Diglyceride kinase theta" EXACT [UniProtKB:P52824] synonym: "EC 2.7.1.107" EXACT [UniProtKB:P52824] xref: EMBL:AAA98749.1 xref: UniProtKB:P52824 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017572 ! DGKQ_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055504 name: NDST2_HUMAN def: "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2" [UniProtKB:P52849] synonym: "EC 2.8.2.8" EXACT [UniProtKB:P52849] synonym: "Glucosaminyl N-deacetylase/N-sulfotransferase 2" EXACT [UniProtKB:P52849] synonym: "N-heparan sulfate sulfotransferase 2" EXACT [UniProtKB:P52849] synonym: "N-HSST 2" EXACT [UniProtKB:P52849] synonym: "NDST-2" EXACT [UniProtKB:P52849] xref: EMBL:AAB97086.1 xref: EMBL:AAC27120.1 xref: EMBL:AAH35711.1 xref: EMBL:AAI10589.1 xref: EMBL:AAI10590.1 xref: EMBL:BAD92107.1 xref: UniProtKB:P52849 xref: UniProtKB:Q2TB32 xref: UniProtKB:Q59H89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018742 ! NDST2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001748 ! sulfotransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008262 ! [heparan sulfate]-glucosamine N-sulfotransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000887 ! cellular process [Term] id: CCO:B0055505 name: NUP98_HUMAN def: "Nuclear pore complex protein Nup98-Nup96 precursor" [UniProtKB:P52948] xref: EMBL:AAC50366.1 xref: EMBL:AAD22395.1 xref: EMBL:AAD22396.1 xref: EMBL:AAF19342.1 xref: EMBL:AAH12906.1 xref: EMBL:AAH41136.1 xref: EMBL:AAL56659.1 xref: EMBL:AAP36013.1 xref: EMBL:BAB18537.1 xref: EMBL:CAB63736.1 xref: EMBL:CAB70842.1 xref: UniProtKB:P52948 xref: UniProtKB:Q8IUT2 xref: UniProtKB:Q8WYB0 xref: UniProtKB:Q96E54 xref: UniProtKB:Q9H3Q4 xref: UniProtKB:Q9NT02 xref: UniProtKB:Q9UF57 xref: UniProtKB:Q9UHX0 xref: UniProtKB:Q9Y6J4 xref: UniProtKB:Q9Y6J5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018890 ! NUP98_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:I0016215 ! nup107-nup160-1 physical interaction relationship: participates_in CCO:I0016216 ! nup133-nup160-1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0068931 ! NUP98_HUMAN-Phosphoserine608 relationship: transforms_into CCO:B0068932 ! NUP98_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0068933 ! NUP98_HUMAN-Phosphoserine623 relationship: transforms_into CCO:B0068934 ! NUP98_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0068935 ! NUP98_HUMAN-Phosphoserine888 relationship: transforms_into CCO:B0068936 ! NUP98_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0068937 ! NUP98_HUMAN-Phosphothreonine1000 relationship: transforms_into CCO:B0068938 ! NUP98_HUMAN-Phosphoserine1023 relationship: transforms_into CCO:B0068939 ! NUP98_HUMAN-Phosphoserine1028 relationship: transforms_into CCO:B0068940 ! NUP98_HUMAN-Phosphoserine1043 relationship: transforms_into CCO:B0068941 ! NUP98_HUMAN-Phosphoserine1060 relationship: transforms_into CCO:B0068942 ! NUP98_HUMAN-Phosphoserine1064 relationship: transforms_into CCO:B0068943 ! NUP98_HUMAN-Phosphothreonine1070 [Term] id: CCO:B0055506 name: NKX25_HUMAN def: "Homeobox protein Nkx-2.5" [UniProtKB:P52952] synonym: "Cardiac-specific homeobox" EXACT [UniProtKB:P52952] synonym: "Homeobox protein CSX" EXACT [UniProtKB:P52952] synonym: "Homeobox protein NK-2 homolog E" EXACT [UniProtKB:P52952] xref: EMBL:AAC50470.1 xref: EMBL:AAH25711.1 xref: EMBL:BAA35181.1 xref: UniProtKB:P52952 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018797 ! NKX2-5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0018547 ! nkx2_5-camta2 colocalization relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055507 name: LBX1_HUMAN def: "Transcription factor LBX1" [UniProtKB:P52954] synonym: "Ladybird homeobox protein homolog 1" EXACT [UniProtKB:P52954] xref: EMBL:AAH69156.1 xref: EMBL:CAA62342.1 xref: EMBL:CAH72508.2 xref: UniProtKB:P52954 xref: UniProtKB:Q05BB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018460 ! LBX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation [Term] id: CCO:B0055508 name: ARFP2_HUMAN def: "Arfaptin-2" [UniProtKB:P53365] synonym: "ADP-ribosylation factor-interacting protein 2" EXACT [UniProtKB:P53365] synonym: "Partner of RAC1" EXACT [UniProtKB:P53365] synonym: "Protein POR1" EXACT [UniProtKB:P53365] xref: EMBL:AAA97924.1 xref: EMBL:AAH00392.1 xref: EMBL:CAA66179.1 xref: UniProtKB:P53365 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017010 ! ARFIP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_function CCO:F0007332 ! Rac GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000489 ! cell cortex relationship: participates_in CCO:I0015210 ! arfip2-dtnbp1 physical interaction relationship: participates_in CCO:I0015761 ! arfip2-itgb3bp physical interaction relationship: participates_in CCO:I0017511 ! rac1-arfaptin2 direct interaction relationship: participates_in CCO:I0018197 ! rac1-arfip2-2 physical interaction relationship: participates_in CCO:I0018330 ! arfip2-arfip2 physical interaction relationship: participates_in CCO:I0018331 ! rac1-arfip2-3 physical interaction relationship: participates_in CCO:I0018506 ! arf6-arfip2-1 physical interaction relationship: participates_in CCO:I0018651 ! rac1-arfip2 physical interaction relationship: participates_in CCO:I0018652 ! arf6-arfip2-3 physical interaction relationship: participates_in CCO:I0018661 ! arf6-arfip2-2 physical interaction relationship: participates_in CCO:I0018662 ! rac1-arfip2-1 physical interaction relationship: participates_in CCO:I0018663 ! arfip2-arf6-3 physical interaction relationship: participates_in CCO:I0018664 ! arf3-arfip2-1 physical interaction relationship: participates_in CCO:I0018745 ! arfip2-rac1-1 direct interaction relationship: participates_in CCO:I0018746 ! arfip2-rac1-2 direct interaction relationship: participates_in CCO:I0018747 ! arfip2-rac1-3 direct interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055509 name: CO4A4_HUMAN def: "Collagen alpha-4(IV) chain precursor" [UniProtKB:P53420] xref: EMBL:AAY14670.1 xref: EMBL:AAY24061.1 xref: EMBL:BAA04214.1 xref: EMBL:BAA25065.1 xref: EMBL:CAA56943.1 xref: EMBL:CAA76763.1 xref: UniProtKB:P53420 xref: UniProtKB:Q53RW9 xref: UniProtKB:Q53S42 xref: UniProtKB:Q53WR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017424 ! COL4A4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002035 ! long-term strengthening of neuromuscular junction relationship: transforms_into CCO:B0064446 ! CO4A4_HUMAN-Phosphoserine139 [Term] id: CCO:B0055510 name: AP2S1_HUMAN def: "AP-2 complex subunit sigma-1" [UniProtKB:P53680] synonym: "Adapter-related protein complex 2 sigma-1 subunit" EXACT [UniProtKB:P53680] synonym: "Clathrin assembly protein 2 small chain" EXACT [UniProtKB:P53680] synonym: "Clathrin coat assembly protein AP17" EXACT [UniProtKB:P53680] synonym: "Clathrin coat-associated protein AP17" EXACT [UniProtKB:P53680] synonym: "HA2 17 kDa subunit" EXACT [UniProtKB:P53680] synonym: "Plasma membrane adaptor AP-2 17 kDa protein" EXACT [UniProtKB:P53680] synonym: "Sigma2-adaptin" EXACT [UniProtKB:P53680] xref: EMBL:AAH06337.1 xref: EMBL:CAA09018.1 xref: EMBL:CAA09019.1 xref: EMBL:CAA65782.1 xref: UniProtKB:O75977 xref: UniProtKB:P53680 xref: UniProtKB:Q6PK67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016978 ! AP2S1_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000967 ! AP-2 adaptor complex relationship: participates_in CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:B0055511 name: RPAB4_HUMAN def: "DNA-directed RNA polymerases I, II, and III subunit RPABC4" [UniProtKB:P53803] synonym: "ABC10-alpha" EXACT [UniProtKB:P53803] synonym: "DNA-directed RNA polymerase II subunit K" EXACT [UniProtKB:P53803] synonym: "DNA-directed RNA polymerases I, II, and III 7.0 kDa polypeptide" EXACT [UniProtKB:P53803] synonym: "RNA polymerases I, II, and III subunit ABC4" EXACT [UniProtKB:P53803] synonym: "RPB10alpha" EXACT [UniProtKB:P53803] synonym: "RPB7.0" EXACT [UniProtKB:P53803] xref: EMBL:AAH00806.1 xref: EMBL:AAH18157.1 xref: EMBL:CAA87656.1 xref: EMBL:CAB91873.1 xref: UniProtKB:P53803 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019778 ! POLR2K_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:P0000656 ! regulation of transcription from RNA polymerase I promoter [Term] id: CCO:B0055512 name: RCAN1_HUMAN def: "Calcipressin-1" [UniProtKB:P53805] synonym: "Adapt78" EXACT [UniProtKB:P53805] synonym: "Down syndrome critical region protein 1" EXACT [UniProtKB:P53805] synonym: "MCIP1" EXACT [UniProtKB:P53805] synonym: "Myocyte-enriched calcineurin-interacting protein 1" EXACT [UniProtKB:P53805] synonym: "Regulator of calcineurin 1" EXACT [UniProtKB:P53805] xref: EMBL:AAB81557.1 xref: EMBL:AAB84370.1 xref: EMBL:AAB84371.2 xref: EMBL:AAB84372.1 xref: EMBL:AAF21218.1 xref: EMBL:AAH02864.1 xref: EMBL:AAK92478.1 xref: EMBL:AAP36027.1 xref: EMBL:AAP96743.1 xref: EMBL:BAG52494.1 xref: EMBL:CAG33159.1 xref: EMBL:EAX09779.1 xref: UniProtKB:O00582 xref: UniProtKB:O00583 xref: UniProtKB:P53805 xref: UniProtKB:Q53XT0 xref: UniProtKB:Q6IBC6 xref: UniProtKB:Q7Z555 xref: UniProtKB:Q96R03 xref: UniProtKB:Q9BU69 xref: UniProtKB:Q9UF15 xref: UniProtKB:Q9UME4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019653 ! RCAN1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0055513 name: CACB3_HUMAN def: "Voltage-dependent L-type calcium channel subunit beta-3" [UniProtKB:P54284] synonym: "CAB3" EXACT [UniProtKB:P54284] synonym: "Calcium channel voltage-dependent subunit beta 3" EXACT [UniProtKB:P54284] xref: EMBL:AAA19799.1 xref: EMBL:AAA95958.1 xref: EMBL:AAH41811.1 xref: EMBL:BAA07803.1 xref: EMBL:CAA54055.1 xref: EMBL:CAA54056.1 xref: UniProtKB:P54284 xref: UniProtKB:Q13913 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017210 ! CACNB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017974 ! cacnb3-syt1-1 physical interaction relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: transforms_into CCO:B0064045 ! CACB3_HUMAN-Phosphotyrosine171 [Term] id: CCO:B0055514 name: AAPK2_HUMAN def: "5'-AMP-activated protein kinase catalytic subunit alpha-2" [UniProtKB:P54646] synonym: "AMPK alpha-2 chain" EXACT [UniProtKB:P54646] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P54646] xref: EMBL:AAA64745.1 xref: EMBL:AAH69680.1 xref: EMBL:AAH69740.1 xref: EMBL:AAH69823.1 xref: EMBL:CAC17574.2 xref: UniProtKB:P54646 xref: UniProtKB:Q9H1E8 xref: UniProtKB:Q9UD43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016870 ! PRKAA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation relationship: transforms_into CCO:B0065257 ! AAPK2_HUMAN-Phosphothreonine172 relationship: transforms_into CCO:B0065258 ! AAPK2_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0065259 ! AAPK2_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0065260 ! AAPK2_HUMAN-Phosphothreonine258 relationship: transforms_into CCO:B0065261 ! AAPK2_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0065262 ! AAPK2_HUMAN-Phosphoserine491 relationship: transforms_into CCO:B0065263 ! AAPK2_HUMAN-Phosphoserine500 [Term] id: CCO:B0055515 name: PDE1A_HUMAN def: "Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A" [UniProtKB:P54750] synonym: "61 kDa Cam-PDE" EXACT [UniProtKB:P54750] synonym: "Cam-PDE 1A" EXACT [UniProtKB:P54750] synonym: "EC 3.1.4.17" EXACT [UniProtKB:P54750] synonym: "hCam-1" EXACT [UniProtKB:P54750] xref: EMBL:AAC50436.1 xref: EMBL:AAH22480.1 xref: EMBL:BAB20049.1 xref: EMBL:BAB20050.1 xref: EMBL:BAB20051.1 xref: EMBL:BAB20052.1 xref: EMBL:BAB20053.1 xref: EMBL:BAB20054.1 xref: EMBL:BAB20055.1 xref: EMBL:BAB20056.1 xref: EMBL:BAB20057.1 xref: EMBL:CAB53703.1 xref: EMBL:CAC82208.1 xref: UniProtKB:P54750 xref: UniProtKB:Q86VZ0 xref: UniProtKB:Q9C0K8 xref: UniProtKB:Q9C0K9 xref: UniProtKB:Q9C0L0 xref: UniProtKB:Q9C0L1 xref: UniProtKB:Q9C0L2 xref: UniProtKB:Q9C0L3 xref: UniProtKB:Q9C0L4 xref: UniProtKB:Q9UFX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019332 ! PDE1A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000588 ! calmodulin-dependent cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055516 name: DVL1L_HUMAN def: "Segment polarity protein dishevelled homolog DVL-1-like" [UniProtKB:P54792] synonym: "Dishevelled-1-like" EXACT [UniProtKB:P54792] synonym: "DSH homolog 1-like" EXACT [UniProtKB:P54792] xref: EMBL:AAC50682.1 xref: UniProtKB:P54792 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017644 ! DVL1L1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0055517 name: PRRX1_HUMAN def: "Paired mesoderm homeobox protein 1" [UniProtKB:P54821] synonym: "Homeobox protein PHOX1" EXACT [UniProtKB:P54821] synonym: "Paired-related homeobox protein 1" EXACT [UniProtKB:P54821] synonym: "PRX-1" EXACT [UniProtKB:P54821] xref: EMBL:AAA60085.1 xref: EMBL:AAH74993.1 xref: UniProtKB:O60807 xref: UniProtKB:P54821 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019521 ! PRRX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069559 ! PRRX1_HUMAN-Phosphoserine197 [Term] id: CCO:B0055518 name: NRL_HUMAN def: "Neural retina-specific leucine zipper protein" [UniProtKB:P54845] synonym: "D14S46E" EXACT [UniProtKB:P54845] synonym: "NRL" EXACT [UniProtKB:P54845] xref: EMBL:AAA59948.1 xref: EMBL:AAA96828.1 xref: EMBL:AAB82768.1 xref: EMBL:AAH12395.1 xref: UniProtKB:P54845 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018870 ! NRL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000795 ! regulation of rhodopsin gene expression relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055519 name: EMP1_HUMAN def: "Epithelial membrane protein 1" [UniProtKB:P54849] synonym: "CL-20" EXACT [UniProtKB:P54849] synonym: "EMP-1" EXACT [UniProtKB:P54849] synonym: "Protein B4B" EXACT [UniProtKB:P54849] synonym: "Tumor-associated membrane protein" EXACT [UniProtKB:P54849] xref: EMBL:AAC51207.1 xref: EMBL:AAC51783.1 xref: EMBL:AAH47300.1 xref: EMBL:CAA69217.1 xref: EMBL:CAA90627.1 xref: UniProtKB:O00681 xref: UniProtKB:P54849 xref: UniProtKB:Q13481 xref: UniProtKB:Q13834 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017701 ! EMP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055520 name: EMP2_HUMAN def: "Epithelial membrane protein 2" [UniProtKB:P54851] synonym: "EMP-2" EXACT [UniProtKB:P54851] synonym: "Protein XMP" EXACT [UniProtKB:P54851] xref: EMBL:AAC51779.1 xref: EMBL:AAH09687.1 xref: EMBL:AAL27085.1 xref: EMBL:CAA64393.1 xref: UniProtKB:P54851 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017702 ! EMP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055521 name: EMP3_HUMAN def: "Epithelial membrane protein 3" [UniProtKB:P54852] synonym: "EMP-3" EXACT [UniProtKB:P54852] synonym: "Hematopoietic neural membrane protein" EXACT [UniProtKB:P54852] synonym: "HNMP-1" EXACT [UniProtKB:P54852] synonym: "Protein YMP" EXACT [UniProtKB:P54852] xref: EMBL:AAC50920.1 xref: EMBL:AAC51730.1 xref: EMBL:AAH09718.1 xref: EMBL:AAP35788.1 xref: EMBL:CAA64394.1 xref: UniProtKB:P54852 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017703 ! EMP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055522 name: DRG2_HUMAN def: "Developmentally-regulated GTP-binding protein 2" [UniProtKB:P55039] synonym: "DRG-2" EXACT [UniProtKB:P55039] xref: EMBL:AAH00493.1 xref: EMBL:CAA56730.1 xref: UniProtKB:P55039 xref: UniProtKB:Q9BWB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017622 ! DRG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015615 ! drg2-rwdd1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064880 ! DRG2_HUMAN-Phosphoserine199 [Term] id: CCO:B0055523 name: GEM_HUMAN def: "GTP-binding protein GEM" [UniProtKB:P55040] synonym: "GTP-binding mitogen-induced T-cell protein" EXACT [UniProtKB:P55040] synonym: "RAS-like protein KIR" EXACT [UniProtKB:P55040] xref: EMBL:AAA64911.1 xref: EMBL:AAC50067.1 xref: EMBL:AAH22010.1 xref: UniProtKB:P55040 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017915 ! GEM_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015097 ! gem-trim23 physical interaction relationship: participates_in CCO:I0015697 ! gem-pdlim7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055524 name: RAD_HUMAN def: "GTP-binding protein RAD" [UniProtKB:P55042] synonym: "RAD1" EXACT [UniProtKB:P55042] synonym: "RAS associated with diabetes" EXACT [UniProtKB:P55042] xref: EMBL:AAA36540.1 xref: EMBL:AAH11645.1 xref: EMBL:AAH57815.1 xref: UniProtKB:P55042 xref: UniProtKB:Q96F39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019614 ! RRAD_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055525 name: NR1H2_HUMAN def: "Oxysterols receptor LXR-beta" [UniProtKB:P55055] synonym: "Liver X receptor beta" EXACT [UniProtKB:P55055] synonym: "Nuclear orphan receptor LXR-beta" EXACT [UniProtKB:P55055] synonym: "Nuclear receptor NER" EXACT [UniProtKB:P55055] synonym: "Nuclear receptor subfamily 1 group H member 2" EXACT [UniProtKB:P55055] synonym: "Ubiquitously-expressed nuclear receptor" EXACT [UniProtKB:P55055] xref: EMBL:AAA58594.1 xref: EMBL:AAA61783.1 xref: EMBL:AAH07790.1 xref: EMBL:AAH33500.1 xref: EMBL:AAH47750.1 xref: EMBL:AAH74500.1 xref: UniProtKB:P55055 xref: UniProtKB:Q12970 xref: UniProtKB:Q5I0Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018851 ! NR1H2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015175 ! mdfi-nr1h2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0055526 name: BI1_HUMAN def: "Bax inhibitor 1" [UniProtKB:P55061] synonym: "BI-1" EXACT [UniProtKB:P55061] synonym: "Testis-enhanced gene transcript protein" EXACT [UniProtKB:P55061] synonym: "Transmembrane BAX inhibitor motif-containing protein 6" EXACT [UniProtKB:P55061] xref: EMBL:AAB87479.1 xref: EMBL:AAH00916.1 xref: EMBL:AAH36203.1 xref: EMBL:AAU29521.1 xref: EMBL:CAA53472.1 xref: UniProtKB:O14938 xref: UniProtKB:P55061 xref: UniProtKB:Q643A7 xref: UniProtKB:Q96J50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017151 ! TEGT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0055527 name: UCN1_HUMAN def: "Urocortin precursor" [UniProtKB:P55089] xref: EMBL:AAC24204.1 xref: EMBL:AAI04471.1 xref: EMBL:AAI04472.1 xref: EMBL:AAY24297.1 xref: EMBL:CAG47040.1 xref: UniProtKB:P55089 xref: UniProtKB:Q6FG64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020403 ! UCN_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0071710 ! UCN1_HUMAN-Valine amide122 [Term] id: CCO:B0055528 name: BMP3B_HUMAN def: "Bone morphogenetic protein 3b precursor" [UniProtKB:P55107] synonym: "BIP" EXACT [UniProtKB:P55107] synonym: "BMP-3b" EXACT [UniProtKB:P55107] synonym: "Bone-inducing protein" EXACT [UniProtKB:P55107] synonym: "GDF-10" EXACT [UniProtKB:P55107] synonym: "Growth/differentiation factor 10" EXACT [UniProtKB:P55107] xref: EMBL:AAL77527.1 xref: EMBL:BAA08452.1 xref: EMBL:BAA08453.1 xref: UniProtKB:P55107 xref: UniProtKB:Q9UCX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017167 ! GDF10_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0055529 name: ELL_HUMAN def: "RNA polymerase II elongation factor ELL" [UniProtKB:P55199] synonym: "Eleven-nineteen lysine-rich leukemia protein" EXACT [UniProtKB:P55199] xref: EMBL:AAA57120.1 xref: EMBL:AAH49195.1 xref: UniProtKB:P55199 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017690 ! ELL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001753 ! positive transcription elongation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064982 ! ELL_HUMAN-Phosphothreonine170 relationship: transforms_into CCO:B0064983 ! ELL_HUMAN-Phosphoserine309 relationship: transforms_into CCO:B0064984 ! ELL_HUMAN-Phosphoserine561 [Term] id: CCO:B0055530 name: CASP7_HUMAN def: "Caspase-7 precursor" [UniProtKB:P55210] synonym: "Apoptotic protease Mch-3" EXACT [UniProtKB:P55210] synonym: "CASP-7" EXACT [UniProtKB:P55210] synonym: "CMH-1" EXACT [UniProtKB:P55210] synonym: "EC 3.4.22.60" EXACT [UniProtKB:P55210] synonym: "ICE-LAP3" EXACT [UniProtKB:P55210] synonym: "ICE-like apoptotic protease 3" EXACT [UniProtKB:P55210] xref: EMBL:AAC50303.1 xref: EMBL:AAC50304.1 xref: EMBL:AAC50346.1 xref: EMBL:AAC50352.1 xref: EMBL:AAC51152.1 xref: EMBL:AAC51153.1 xref: EMBL:AAF21460.1 xref: EMBL:AAH15799.1 xref: EMBL:CAI12638.1 xref: EMBL:CAI16004.1 xref: EMBL:EAW49495.1 xref: UniProtKB:P55210 xref: UniProtKB:Q13364 xref: UniProtKB:Q5SVL0 xref: UniProtKB:Q96BA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017238 ! CASP7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:I0016259 ! birc2-casp7-1 physical interaction relationship: participates_in CCO:I0017953 ! birc4-casp7-1 physical interaction relationship: participates_in CCO:I0018788 ! birc2-casp7-2 physical interaction relationship: participates_in CCO:I0019323 ! birc4-casp7-2 direct interaction relationship: participates_in CCO:P0000839 ! apoptotic program [Term] id: CCO:B0055531 name: CASP6_HUMAN def: "Caspase-6 precursor" [UniProtKB:P55212] synonym: "Apoptotic protease Mch-2" EXACT [UniProtKB:P55212] synonym: "CASP-6" EXACT [UniProtKB:P55212] synonym: "EC 3.4.22.59" EXACT [UniProtKB:P55212] xref: EMBL:AAC50168.1 xref: EMBL:AAC50169.1 xref: EMBL:AAH00305.1 xref: EMBL:AAH04460.1 xref: EMBL:AAO63494.1 xref: UniProtKB:P55212 xref: UniProtKB:Q9BQE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017237 ! CASP6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020268 ! casp6-chd3 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0064076 ! CASP6_HUMAN-Phosphoserine257 [Term] id: CCO:B0055532 name: DSRAD_HUMAN def: "Double-stranded RNA-specific adenosine deaminase" [UniProtKB:P55265] synonym: "136 kDa double-stranded RNA-binding protein" EXACT [UniProtKB:P55265] synonym: "DRADA" EXACT [UniProtKB:P55265] synonym: "EC 3.5.4.-" EXACT [UniProtKB:P55265] synonym: "IFI-4" EXACT [UniProtKB:P55265] synonym: "Interferon-inducible protein 4" EXACT [UniProtKB:P55265] synonym: "K88DSRBP" EXACT [UniProtKB:P55265] synonym: "P136" EXACT [UniProtKB:P55265] xref: EMBL:AAB06697.1 xref: EMBL:AAB97116.1 xref: EMBL:AAB97117.1 xref: EMBL:AAB97118.1 xref: EMBL:AAC13782.1 xref: EMBL:AAH38227.1 xref: EMBL:CAA55967.1 xref: EMBL:CAA55968.1 xref: EMBL:CAA67169.1 xref: EMBL:CAA67170.1 xref: EMBL:CAD98075.1 xref: EMBL:CAE45853.1 xref: UniProtKB:O15223 xref: UniProtKB:O43859 xref: UniProtKB:O43860 xref: UniProtKB:P55265 xref: UniProtKB:Q9BYM3 xref: UniProtKB:Q9BYM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017624 ! ADAR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001363 ! gene silencing by RNA relationship: transforms_into CCO:B0064883 ! DSRAD_HUMAN-Phosphothreonine601 relationship: transforms_into CCO:B0064884 ! DSRAD_HUMAN-Phosphoserine614 relationship: transforms_into CCO:B0064885 ! DSRAD_HUMAN-Phosphothreonine808 relationship: transforms_into CCO:B0064886 ! DSRAD_HUMAN-Phosphothreonine818 relationship: transforms_into CCO:B0064887 ! DSRAD_HUMAN-Phosphoserine823 relationship: transforms_into CCO:B0064888 ! DSRAD_HUMAN-Phosphoserine825 [Term] id: CCO:B0055533 name: CADH4_HUMAN def: "Cadherin-4 precursor" [UniProtKB:P55283] synonym: "R-CAD" EXACT [UniProtKB:P55283] synonym: "R-cadherin" EXACT [UniProtKB:P55283] synonym: "Retinal cadherin" EXACT [UniProtKB:P55283] xref: EMBL:AAA35627.1 xref: EMBL:AAI01652.1 xref: EMBL:AAI12151.1 xref: EMBL:CAC26840.2 xref: EMBL:CAH73749.1 xref: EMBL:CAI16510.1 xref: EMBL:CAI19181.1 xref: UniProtKB:P55283 xref: UniProtKB:Q2M208 xref: UniProtKB:Q5VZ44 xref: UniProtKB:Q9BZ05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017213 ! CDH4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002548 ! positive regulation of axon extension [Term] id: CCO:B0055534 name: CAD13_HUMAN def: "Cadherin-13 precursor" [UniProtKB:P55290] synonym: "H-cadherin" EXACT [UniProtKB:P55290] synonym: "Heart cadherin" EXACT [UniProtKB:P55290] synonym: "P105" EXACT [UniProtKB:P55290] synonym: "T-cad" EXACT [UniProtKB:P55290] synonym: "T-cadherin" EXACT [UniProtKB:P55290] synonym: "Truncated cadherin" EXACT [UniProtKB:P55290] xref: EMBL:AAA35624.1 xref: EMBL:AAB18911.1 xref: EMBL:AAB18912.1 xref: EMBL:AAH28624.1 xref: EMBL:AAH30653.1 xref: EMBL:BAA32411.1 xref: UniProtKB:P55290 xref: UniProtKB:Q6GTW4 xref: UniProtKB:Q8TBX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017212 ! CDH13_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_function CCO:F0004336 ! low-density lipoprotein binding relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_function CCO:F0008230 ! adiponectin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation relationship: participates_in CCO:P0000509 ! positive regulation of cell-matrix adhesion relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001131 ! Rac protein signal transduction relationship: participates_in CCO:P0001243 ! regulation of endocytosis relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002033 ! regulation of epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0002248 ! keratinocyte proliferation relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling relationship: participates_in CCO:P0003225 ! low density lipoprotein mediated signaling [Term] id: CCO:B0055535 name: PKNX1_HUMAN def: "Homeobox protein PKNOX1" [UniProtKB:P55347] synonym: "Homeobox protein PREP-1" EXACT [UniProtKB:P55347] synonym: "PBX/knotted homeobox 1" EXACT [UniProtKB:P55347] xref: EMBL:AAC51243.1 xref: EMBL:AAN34940.1 xref: EMBL:BAA95533.1 xref: EMBL:CAA73934.1 xref: UniProtKB:O00528 xref: UniProtKB:P55347 xref: UniProtKB:Q8IWT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019422 ! PKNOX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055536 name: PAX9_HUMAN def: "Paired box protein Pax-9" [UniProtKB:P55771] xref: EMBL:AAH01159.1 xref: EMBL:CAA63436.1 xref: EMBL:CAB41533.1 xref: UniProtKB:P55771 xref: UniProtKB:Q99582 xref: UniProtKB:Q9UQR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019312 ! PAX9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055537 name: CCL23_HUMAN def: "C-C motif chemokine 23 precursor" [UniProtKB:P55773] synonym: "CK-beta-8" EXACT [UniProtKB:P55773] synonym: "CKB-8" EXACT [UniProtKB:P55773] synonym: "Macrophage inflammatory protein 3" EXACT [UniProtKB:P55773] synonym: "MIP-3" EXACT [UniProtKB:P55773] synonym: "MPIF-1" EXACT [UniProtKB:P55773] synonym: "Myeloid progenitor inhibitory factor 1" EXACT [UniProtKB:P55773] synonym: "Small-inducible cytokine A23" EXACT [UniProtKB:P55773] xref: EMBL:AAB51134.1 xref: EMBL:AAC63326.1 xref: EMBL:AAC63327.1 xref: EMBL:AAD00161.1 xref: EMBL:AAD10846.1 xref: EMBL:AAH93970.1 xref: UniProtKB:O00174 xref: UniProtKB:O75950 xref: UniProtKB:P55773 xref: UniProtKB:Q52LD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017268 ! CCL23_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055538 name: GFRA1_HUMAN def: "GDNF family receptor alpha-1 precursor" [UniProtKB:P56159] synonym: "GDNF receptor alpha" EXACT [UniProtKB:P56159] synonym: "GDNFR-alpha" EXACT [UniProtKB:P56159] synonym: "GFR-alpha-1" EXACT [UniProtKB:P56159] synonym: "RET ligand 1" EXACT [UniProtKB:P56159] synonym: "TGF-beta-related neurotrophic factor receptor 1" EXACT [UniProtKB:P56159] xref: EMBL:AAB71811.1 xref: EMBL:AAB97371.1 xref: EMBL:AAC14431.1 xref: EMBL:AAC39692.1 xref: EMBL:AAC39693.1 xref: EMBL:AAC51646.1 xref: EMBL:AAH14962.1 xref: UniProtKB:O15507 xref: UniProtKB:O43912 xref: UniProtKB:P56159 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017916 ! GFRA1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0003058 ! glial cell line-derived neurotrophic factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0055539 name: DLX1_HUMAN def: "Homeobox protein DLX-1" [UniProtKB:P56177] xref: EMBL:AAH36189.2 xref: EMBL:AAO91939.1 xref: UniProtKB:P56177 xref: UniProtKB:Q53ZU4 xref: UniProtKB:Q8IYB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017584 ! DLX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055540 name: TPTE_HUMAN def: "Putative tyrosine-protein phosphatase TPTE" [UniProtKB:P56180] synonym: "Cancer/testis antigen 44" EXACT [UniProtKB:P56180] synonym: "CT44" EXACT [UniProtKB:P56180] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P56180] synonym: "Transmembrane phosphatase with tensin homology" EXACT [UniProtKB:P56180] synonym: "Tumor antigen BJ-HCC-5" EXACT [UniProtKB:P56180] xref: EMBL:AAC34574.1 xref: EMBL:AAH28719.1 xref: EMBL:AAP45143.1 xref: EMBL:AAP45144.1 xref: EMBL:AAP45145.1 xref: EMBL:AAQ06674.1 xref: EMBL:CAB90528.1 xref: UniProtKB:P56180 xref: UniProtKB:Q6XPS4 xref: UniProtKB:Q6XPS5 xref: UniProtKB:Q71JA8 xref: UniProtKB:Q8NCS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020334 ! TPTE_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055541 name: ITA1_HUMAN def: "Integrin alpha-1 precursor" [UniProtKB:P56199] synonym: "CD49 antigen-like family member A" EXACT [UniProtKB:P56199] synonym: "CD49a antigen" EXACT [UniProtKB:P56199] synonym: "Laminin and collagen receptor" EXACT [UniProtKB:P56199] synonym: "VLA-1" EXACT [UniProtKB:P56199] xref: UniProtKB:P56199 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018331 ! ITGA1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0055542 name: ARP19_HUMAN def: "cAMP-regulated phosphoprotein 19" [UniProtKB:P56211] synonym: "ARPP-19" EXACT [UniProtKB:P56211] xref: EMBL:AAD52044.1 xref: EMBL:AAH03418.1 xref: EMBL:AAI00016.1 xref: EMBL:CAA11115.1 xref: EMBL:CAD89929.1 xref: EMBL:CAG33413.1 xref: UniProtKB:P56211 xref: UniProtKB:Q6IAM2 xref: UniProtKB:Q86TA6 xref: UniProtKB:Q9UD70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017046 ! ARPP19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002519 ! positive regulation of gluconeogenesis relationship: transforms_into CCO:B0063606 ! ARP19_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0063607 ! ARP19_HUMAN-N-acetylmethionine17 relationship: transforms_into CCO:B0063608 ! ARP19_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0063609 ! ARP19_HUMAN-Phosphoserine104 [Term] id: CCO:B0055543 name: MAZ_HUMAN def: "Myc-associated zinc finger protein" [UniProtKB:P56270] synonym: "MAZI" EXACT [UniProtKB:P56270] synonym: "Pur-1" EXACT [UniProtKB:P56270] synonym: "Purine-binding transcription factor" EXACT [UniProtKB:P56270] synonym: "ZF87" EXACT [UniProtKB:P56270] synonym: "ZIF87" EXACT [UniProtKB:P56270] xref: EMBL:AAB04121.1 xref: EMBL:BAA12728.1 xref: EMBL:BAA33064.1 xref: UniProtKB:P56270 xref: UniProtKB:Q15703 xref: UniProtKB:Q99443 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018575 ! MAZ_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055544 name: P2RX3_HUMAN def: "P2X purinoceptor 3" [UniProtKB:P56373] synonym: "ATP receptor" EXACT [UniProtKB:P56373] synonym: "P2X3" EXACT [UniProtKB:P56373] synonym: "Purinergic receptor" EXACT [UniProtKB:P56373] xref: EMBL:BAA76515.1 xref: EMBL:CAA68947.1 xref: UniProtKB:P56373 xref: UniProtKB:Q9UQB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019260 ! P2RX3_human relationship: has_function CCO:F0000165 ! purinergic nucleotide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001273 ! ATP-gated cation channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling [Term] id: CCO:B0055545 name: CAV3_HUMAN def: "Caveolin-3" [UniProtKB:P56539] synonym: "M-caveolin" EXACT [UniProtKB:P56539] xref: EMBL:AAC14931.1 xref: EMBL:AAC39756.1 xref: EMBL:AAC39758.1 xref: EMBL:AAH69368.1 xref: EMBL:AAI02034.1 xref: EMBL:AAI02037.1 xref: EMBL:AAI02038.1 xref: EMBL:CAA75042.1 xref: UniProtKB:P56539 xref: UniProtKB:Q3T1A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017244 ! CAV3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003551 ! sodium channel regulator activity relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000761 ! dystrophin-associated glycoprotein complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001002 ! T-tubule relationship: located_in CCO:C0001638 ! sarcolemma relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0002210 ! negative regulation of MAPKKK cascade [Term] id: CCO:B0055546 name: NDK5_HUMAN def: "Nucleoside diphosphate kinase homolog 5" [UniProtKB:P56597] synonym: "Inhibitor of p53-induced apoptosis-beta" EXACT [UniProtKB:P56597] synonym: "IPIA-beta" EXACT [UniProtKB:P56597] synonym: "NDK-H 5" EXACT [UniProtKB:P56597] synonym: "NDP kinase homolog 5" EXACT [UniProtKB:P56597] synonym: "nm23-H5" EXACT [UniProtKB:P56597] synonym: "Testis-specific nm23 homolog" EXACT [UniProtKB:P56597] xref: EMBL:AAC64358.1 xref: EMBL:AAC69440.1 xref: EMBL:AAH26182.1 xref: EMBL:CAA75226.1 xref: UniProtKB:P56597 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018738 ! NME5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014974 ! dydc1-nme5 physical interaction relationship: participates_in CCO:I0015478 ! mgc16186-nme5 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0068528 ! NDK5_HUMAN-Phosphotyrosine58 [Term] id: CCO:B0055547 name: SOX10_HUMAN def: "Transcription factor SOX-10" [UniProtKB:P56693] xref: EMBL:AAH02824.1 xref: EMBL:AAH07595.1 xref: EMBL:AAV38832.1 xref: EMBL:CAA04576.1 xref: EMBL:CAB62982.1 xref: EMBL:CAG30470.1 xref: UniProtKB:P56693 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019989 ! SOX10_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018408 ! nmi-sox10-1 physical interaction relationship: participates_in CCO:I0018409 ! sox10-nmi-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055548 name: WNT3_HUMAN def: "Proto-oncogene protein Wnt-3 precursor" [UniProtKB:P56703] xref: EMBL:AAG38657.1 xref: EMBL:AAI12117.1 xref: EMBL:AAI12119.1 xref: EMBL:AAI14220.1 xref: EMBL:BAB70502.1 xref: UniProtKB:P56703 xref: UniProtKB:Q2M237 xref: UniProtKB:Q9H1J9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020488 ! WNT3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0055549 name: WNT3A_HUMAN def: "Protein Wnt-3a precursor" [UniProtKB:P56704] xref: EMBL:AAI03923.1 xref: EMBL:BAB61052.1 xref: EMBL:BAB71136.1 xref: EMBL:CAI23122.1 xref: UniProtKB:P56704 xref: UniProtKB:Q3SY80 xref: UniProtKB:Q969P2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020487 ! WNT3A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002409 ! regulation of cell differentiation relationship: participates_in CCO:P0002772 ! somatic stem cell division [Term] id: CCO:B0055550 name: WNT4_HUMAN def: "Protein Wnt-4 precursor" [UniProtKB:P56705] xref: EMBL:AAG38658.1 xref: EMBL:AAH57781.1 xref: EMBL:AAK25765.1 xref: EMBL:AAK50427.1 xref: EMBL:AAK51699.1 xref: EMBL:AAQ89306.1 xref: EMBL:AAV38928.1 xref: EMBL:CAI19848.1 xref: EMBL:CAI22251.1 xref: UniProtKB:P56705 xref: UniProtKB:Q5TZQ0 xref: UniProtKB:Q96T81 xref: UniProtKB:Q9BXF5 xref: UniProtKB:Q9H1J8 xref: UniProtKB:Q9UJM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020489 ! WNT4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0055551 name: WNT7B_HUMAN def: "Protein Wnt-7b precursor" [UniProtKB:P56706] xref: EMBL:AAH34923.1 xref: EMBL:AAN32640.1 xref: EMBL:BAB68399.1 xref: UniProtKB:P56706 xref: UniProtKB:Q96Q12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020494 ! WNT7B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation [Term] id: CCO:B0055552 name: RP1_HUMAN def: "Oxygen-regulated protein 1" [UniProtKB:P56715] synonym: "Retinitis pigmentosa 1 protein" EXACT [UniProtKB:P56715] synonym: "Retinitis pigmentosa RP1 protein" EXACT [UniProtKB:P56715] xref: EMBL:AAD42072.1 xref: EMBL:AAD44197.1 xref: EMBL:AAD44198.1 xref: EMBL:AAD46769.1 xref: EMBL:AAD46774.1 xref: UniProtKB:P56715 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019775 ! RP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000481 ! cilium relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055553 name: GSC_HUMAN def: "Homeobox protein goosecoid" [UniProtKB:P56915] xref: EMBL:AAH63580.1 xref: EMBL:AAO18645.1 xref: UniProtKB:P56915 xref: UniProtKB:Q86YR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018083 ! GSC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055554 name: NRG3_HUMAN def: "Pro-neuregulin-3, membrane-bound isoform precursor" [UniProtKB:P56975] synonym: "Pro-NRG3" EXACT [UniProtKB:P56975] xref: EMBL:AAY17216.1 xref: EMBL:ABG77979.1 xref: EMBL:CAH70641.1 xref: EMBL:CAH71050.1 xref: EMBL:CAH73645.1 xref: EMBL:CAI15622.1 xref: EMBL:CAI17213.1 xref: EMBL:CAI22410.1 xref: UniProtKB:A4D7U1 xref: UniProtKB:P56975 xref: UniProtKB:Q0PEH2 xref: UniProtKB:Q5VYH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018868 ! NRG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0068835 ! NRG3_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0068836 ! NRG3_HUMAN-Phosphoserine119 [Term] id: CCO:B0055555 name: HUNK_HUMAN def: "Hormonally up-regulated neu tumor-associated kinase" [UniProtKB:P57058] synonym: "B19" EXACT [UniProtKB:P57058] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P57058] synonym: "Serine/threonine-protein kinase MAK-V" EXACT [UniProtKB:P57058] xref: EMBL:CAB71146.1 xref: UniProtKB:P57058 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018174 ! HUNK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055556 name: PRD15_HUMAN def: "PR domain zinc finger protein 15" [UniProtKB:P57071] synonym: "PR domain-containing protein 15" EXACT [UniProtKB:P57071] synonym: "Zinc finger protein 298" EXACT [UniProtKB:P57071] xref: EMBL:AAF78093.1 xref: EMBL:AAL60596.1 xref: EMBL:AAL85487.2 xref: EMBL:AAM53515.1 xref: EMBL:AAM53516.1 xref: EMBL:BAA95527.1 xref: UniProtKB:P57071 xref: UniProtKB:Q8N0X3 xref: UniProtKB:Q8NEX0 xref: UniProtKB:Q9NQV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019491 ! PRDM15_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055557 name: SOX8_HUMAN def: "Transcription factor SOX-8" [UniProtKB:P57073] xref: EMBL:AAF35886.1 xref: EMBL:AAF37424.1 xref: EMBL:AAH31797.1 xref: EMBL:AAK61260.1 xref: EMBL:CAB75612.1 xref: UniProtKB:P57073 xref: UniProtKB:Q9NZW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019994 ! SOX8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055558 name: SYJ2B_HUMAN def: "Synaptojanin-2-binding protein" [UniProtKB:P57105] synonym: "Mitochondrial outer membrane protein 25" EXACT [UniProtKB:P57105] xref: EMBL:AAH07704.1 xref: EMBL:AAT01566.1 xref: EMBL:BAA92098.1 xref: EMBL:EAW81032.1 xref: UniProtKB:P57105 xref: UniProtKB:Q49SH3 xref: UniProtKB:Q96IA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020086 ! SYNJ2BP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:B0055559 name: KLF3_HUMAN def: "Krueppel-like factor 3" [UniProtKB:P57682] synonym: "Basic krueppel-like factor" EXACT [UniProtKB:P57682] synonym: "CACCC-box-binding protein BKLF" EXACT [UniProtKB:P57682] synonym: "TEF-2" EXACT [UniProtKB:P57682] xref: EMBL:AAH30662.1 xref: EMBL:AAH51687.1 xref: EMBL:AAK27329.1 xref: EMBL:BAA92271.1 xref: UniProtKB:P57682 xref: UniProtKB:Q6PIR1 xref: UniProtKB:Q86TN0 xref: UniProtKB:Q9P2X6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018418 ! KLF3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067381 ! KLF3_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0067382 ! KLF3_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0067383 ! KLF3_HUMAN-Phosphoserine250 [Term] id: CCO:B0055560 name: RAB25_HUMAN def: "Ras-related protein Rab-25" [UniProtKB:P57735] synonym: "CATX-8" EXACT [UniProtKB:P57735] xref: EMBL:AAF98238.1 xref: EMBL:AAH04416.1 xref: EMBL:AAH09831.1 xref: EMBL:AAH33322.1 xref: EMBL:AAM69362.1 xref: EMBL:CAH72638.1 xref: EMBL:EAW53003.1 xref: UniProtKB:P57735 xref: UniProtKB:Q5VYA2 xref: UniProtKB:Q8NG24 xref: UniProtKB:Q96GB1 xref: UniProtKB:Q9BT12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019582 ! RAB25_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055561 name: SELB_HUMAN def: "Selenocysteine-specific elongation factor" [UniProtKB:P57772] synonym: "Elongation factor sec" EXACT [UniProtKB:P57772] synonym: "Eukaryotic elongation factor, selenocysteine-tRNA-specific" EXACT [UniProtKB:P57772] xref: EMBL:AAG13375.1 xref: UniProtKB:P57772 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019863 ! EEFSEC_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000465 ! selenocysteine incorporation [Term] id: CCO:B0055562 name: FBXW4_HUMAN def: "F-box/WD repeat-containing protein 4" [UniProtKB:P57775] synonym: "Dactylin" EXACT [UniProtKB:P57775] synonym: "F-box and WD-40 domain-containing protein 4" EXACT [UniProtKB:P57775] xref: EMBL:AAG22739.1 xref: EMBL:AAH07380.2 xref: EMBL:AAH63415.1 xref: EMBL:CAI12232.1 xref: EMBL:CAI41027.1 xref: UniProtKB:P57775 xref: UniProtKB:Q5SVS1 xref: UniProtKB:Q96IM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017767 ! FBXW4_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0055563 name: KCNKA_HUMAN def: "Potassium channel subfamily K member 10" [UniProtKB:P57789] synonym: "Outward rectifying potassium channel protein TREK-2" EXACT [UniProtKB:P57789] synonym: "TREK-2 K(+) channel subunit" EXACT [UniProtKB:P57789] xref: EMBL:AAG15191.1 xref: EMBL:AAL95705.1 xref: EMBL:AAL95706.1 xref: UniProtKB:P57789 xref: UniProtKB:Q8TDK7 xref: UniProtKB:Q8TDK8 xref: UniProtKB:Q9HB59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018399 ! KCNK10_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055564 name: CABP4_HUMAN def: "Calcium-binding protein 4" [UniProtKB:P57796] synonym: "CaBP4" EXACT [UniProtKB:P57796] xref: EMBL:AAH33167.1 xref: EMBL:AAK83462.1 xref: UniProtKB:P57796 xref: UniProtKB:Q8N4Z2 xref: UniProtKB:Q8WWY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017205 ! CABP4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000561 ! flagellin-based flagellum relationship: located_in CCO:C0001727 ! terminal button relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055565 name: OR2B6_HUMAN def: "Olfactory receptor 2B6" [UniProtKB:P58173] synonym: "Hs6M1-32" EXACT [UniProtKB:P58173] synonym: "Olfactory receptor 5-40" EXACT [UniProtKB:P58173] synonym: "Olfactory receptor 6-31" EXACT [UniProtKB:P58173] synonym: "Olfactory receptor OR6-4" EXACT [UniProtKB:P58173] synonym: "OR5-40" EXACT [UniProtKB:P58173] synonym: "OR6-31" EXACT [UniProtKB:P58173] xref: EMBL:AAC39628.1 xref: EMBL:AAI09252.1 xref: EMBL:AAI10458.1 xref: EMBL:CAC14158.1 xref: EMBL:DAA04771.1 xref: UniProtKB:O43883 xref: UniProtKB:P58173 xref: UniProtKB:Q6IF89 xref: UniProtKB:Q9H5B0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019086 ! OR2B6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055566 name: OR4D2_HUMAN def: "Olfactory receptor 4D2" [UniProtKB:P58180] synonym: "B-lymphocyte membrane protein BC2009" EXACT [UniProtKB:P58180] synonym: "Olfactory receptor OR17-24" EXACT [UniProtKB:P58180] xref: EMBL:AAK95053.1 xref: EMBL:AAL26785.1 xref: EMBL:BAC06127.1 xref: EMBL:DAA04622.1 xref: UniProtKB:P58180 xref: UniProtKB:Q6IFN8 xref: UniProtKB:Q96R75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019144 ! OR4D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055567 name: O10A3_HUMAN def: "Olfactory receptor 10A3" [UniProtKB:P58181] synonym: "HTPCRX12" EXACT [UniProtKB:P58181] synonym: "Olfactory receptor OR11-97" EXACT [UniProtKB:P58181] xref: EMBL:AAK95119.1 xref: EMBL:BAC05988.1 xref: EMBL:DAA04802.1 xref: UniProtKB:P58181 xref: UniProtKB:Q6IF58 xref: UniProtKB:Q96R11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018898 ! OR10A3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055568 name: O12D2_HUMAN def: "Olfactory receptor 12D2" [UniProtKB:P58182] synonym: "Hs6M1-20" EXACT [UniProtKB:P58182] synonym: "Olfactory receptor OR6-28" EXACT [UniProtKB:P58182] xref: EMBL:AAH69123.1 xref: EMBL:AAI01743.1 xref: EMBL:AAI01747.1 xref: EMBL:CAB44510.1 xref: EMBL:CAI17482.1 xref: EMBL:DAA04921.1 xref: UniProtKB:P58182 xref: UniProtKB:Q6IET9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018938 ! OR12D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055569 name: VSX2_HUMAN def: "Visual system homeobox 2" [UniProtKB:P58304] synonym: "Ceh-10 homeodomain-containing homolog" EXACT [UniProtKB:P58304] synonym: "Homeobox protein CHX10" EXACT [UniProtKB:P58304] xref: EMBL:AAQ01593.1 xref: UniProtKB:P58304 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020466 ! VSX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071819 ! VSX2_HUMAN-N6-acetyllysine11 [Term] id: CCO:B0055570 name: ZN121_HUMAN def: "Zinc finger protein 121" [UniProtKB:P58317] synonym: "Zinc finger protein 20" EXACT [UniProtKB:P58317] xref: UniProtKB:P58317 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020619 ! ZNF121_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055571 name: MTPN_HUMAN def: "Myotrophin" [UniProtKB:P58546] synonym: "Protein V-1" EXACT [UniProtKB:P58546] xref: EMBL:AAH28093.1 xref: UniProtKB:P58546 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018681 ! MTPN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0068321 ! MTPN_HUMAN-N-acetylcysteine2 [Term] id: CCO:B0055572 name: TIRAP_HUMAN def: "Toll/interleukin-1 receptor domain-containing adapter protein" [UniProtKB:P58753] synonym: "Adaptor protein Wyatt" EXACT [UniProtKB:P58753] synonym: "MyD88 adapter-like protein" EXACT [UniProtKB:P58753] synonym: "TIR domain-containing adapter protein" EXACT [UniProtKB:P58753] xref: EMBL:AAH32474.1 xref: EMBL:AAL01160.1 xref: EMBL:AAL05036.1 xref: EMBL:AAL05627.1 xref: EMBL:AAP31973.1 xref: UniProtKB:P58753 xref: UniProtKB:Q8N5E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020276 ! TIRAP_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0016267 ! myd88-tirap-1 physical interaction relationship: participates_in CCO:I0016268 ! tirap-irak2 physical interaction relationship: participates_in CCO:I0016269 ! tirap-tlr4 physical interaction relationship: participates_in CCO:I0019363 ! tirap-myd88 physical interaction relationship: participates_in CCO:I0019364 ! myd88-tirap physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055573 name: RHBL3_HUMAN def: "Rhomboid-related protein 3" [UniProtKB:P58872] synonym: "EC 3.4.21.105" EXACT [UniProtKB:P58872] synonym: "Ventrhoid transmembrane protein" EXACT [UniProtKB:P58872] xref: EMBL:AAI00976.1 xref: EMBL:CAC86145.1 xref: UniProtKB:A6NMH1 xref: UniProtKB:P58872 xref: UniProtKB:Q495Y6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019709 ! RHBDL3_human relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055574 name: NAL12_HUMAN def: "NACHT, LRR and PYD domains-containing protein 12" [UniProtKB:P59046] synonym: "Monarch-1" EXACT [UniProtKB:P59046] synonym: "PYRIN-containing APAF1-like protein 7" EXACT [UniProtKB:P59046] synonym: "Regulated by nitric oxide" EXACT [UniProtKB:P59046] xref: EMBL:AAH28069.1 xref: EMBL:AAK14942.1 xref: EMBL:AAM18227.1 xref: EMBL:AAM75142.1 xref: EMBL:AAM75143.1 xref: EMBL:AAM75144.1 xref: EMBL:AAM75145.1 xref: EMBL:AAO18163.1 xref: UniProtKB:P59046 xref: UniProtKB:Q8NEU4 xref: UniProtKB:Q9BY26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018709 ! NLRP12_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000825 ! release of cytoplasmic sequestered NF-kappaB relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0001513 ! negative regulation of protein amino acid autophosphorylation relationship: participates_in CCO:P0002163 ! negative regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002322 ! regulation of interleukin-18 biosynthetic process relationship: participates_in CCO:P0002350 ! negative regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002536 ! negative regulation of Toll signaling pathway [Term] id: CCO:B0055575 name: RAB15_HUMAN def: "Ras-related protein Rab-15" [UniProtKB:P59190] xref: EMBL:AAH40679.2 xref: EMBL:CAD62353.1 xref: UniProtKB:P59190 xref: UniProtKB:Q86TX7 xref: UniProtKB:Q8IW89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019573 ! RAB15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069670 ! RAB15_HUMAN-Cysteine methyl ester212 [Term] id: CCO:B0055576 name: T2R12_HUMAN def: "Putative Taste receptor type 2 member 12" [UniProtKB:P59531] synonym: "T2R12" EXACT [UniProtKB:P59531] synonym: "T2R26" EXACT [UniProtKB:P59531] synonym: "Taste receptor type 2 member 26" EXACT [UniProtKB:P59531] xref: UniProtKB:P59531 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020094 ! TAS2R12_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055577 name: T2R38_HUMAN def: "Taste receptor type 2 member 38" [UniProtKB:P59533] synonym: "PTC bitter taste receptor" EXACT [UniProtKB:P59533] synonym: "T2R38" EXACT [UniProtKB:P59533] synonym: "T2R61" EXACT [UniProtKB:P59533] xref: EMBL:AAI04934.1 xref: EMBL:AAI04938.1 xref: EMBL:AAM19322.1 xref: EMBL:AAM63545.1 xref: EMBL:AAP14667.1 xref: EMBL:AAU21156.1 xref: UniProtKB:P59533 xref: UniProtKB:P59552 xref: UniProtKB:Q2M3E8 xref: UniProtKB:Q645W3 xref: UniProtKB:Q86UK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020098 ! TAS2R38_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055578 name: T2R39_HUMAN def: "Taste receptor type 2 member 39" [UniProtKB:P59534] synonym: "T2R39" EXACT [UniProtKB:P59534] synonym: "T2R57" EXACT [UniProtKB:P59534] xref: EMBL:AAI00948.1 xref: EMBL:AAI00949.1 xref: EMBL:AAM19321.1 xref: EMBL:AAU21155.1 xref: UniProtKB:P59534 xref: UniProtKB:Q3ZCN6 xref: UniProtKB:Q645W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020099 ! TAS2R39_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055579 name: T2R41_HUMAN def: "Taste receptor type 2 member 41" [UniProtKB:P59536] synonym: "T2R41" EXACT [UniProtKB:P59536] synonym: "T2R59" EXACT [UniProtKB:P59536] xref: EMBL:AAM19323.1 xref: EMBL:AAM63543.1 xref: EMBL:AAU21152.1 xref: UniProtKB:P59536 xref: UniProtKB:P59550 xref: UniProtKB:Q645W7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020100 ! TAS2R41_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055580 name: T2R43_HUMAN def: "Taste receptor type 2 member 43" [UniProtKB:P59537] synonym: "T2R43" EXACT [UniProtKB:P59537] synonym: "T2R52" EXACT [UniProtKB:P59537] xref: EMBL:AAI17424.1 xref: EMBL:AAM19328.1 xref: EMBL:AAM63539.1 xref: EMBL:AAU21145.1 xref: UniProtKB:P59537 xref: UniProtKB:P59546 xref: UniProtKB:Q645X4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020102 ! TAS2R43_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_function CCO:F0005055 ! bitter taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055581 name: T2R44_HUMAN def: "Taste receptor type 2 member 44" [UniProtKB:P59538] synonym: "T2R44" EXACT [UniProtKB:P59538] synonym: "T2R53" EXACT [UniProtKB:P59538] xref: EMBL:AAI17422.1 xref: EMBL:AAM19319.1 xref: EMBL:AAM63540.1 xref: EMBL:AAU21144.1 xref: UniProtKB:P59538 xref: UniProtKB:P59547 xref: UniProtKB:Q17R84 xref: UniProtKB:Q645X5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020103 ! TAS2R44_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055582 name: T2R45_HUMAN def: "Taste receptor type 2 member 45" [UniProtKB:P59539] synonym: "G-protein coupled receptor 59" EXACT [UniProtKB:P59539] synonym: "T2R45" EXACT [UniProtKB:P59539] xref: EMBL:AAM19317.1 xref: UniProtKB:P59539 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020104 ! TAS2R45_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055583 name: T2R46_HUMAN def: "Taste receptor type 2 member 46" [UniProtKB:P59540] synonym: "T2R46" EXACT [UniProtKB:P59540] synonym: "T2R54" EXACT [UniProtKB:P59540] xref: EMBL:AAM19318.1 xref: EMBL:AAM63541.1 xref: EMBL:AAU21143.1 xref: UniProtKB:P59540 xref: UniProtKB:P59548 xref: UniProtKB:Q645X6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020105 ! TAS2R46_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055584 name: T2R47_HUMAN def: "Taste receptor type 2 member 47" [UniProtKB:P59541] synonym: "T2R47" EXACT [UniProtKB:P59541] xref: EMBL:AAM19324.1 xref: EMBL:AAU21142.1 xref: UniProtKB:P59541 xref: UniProtKB:Q645X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020106 ! TAS2R47_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055585 name: T2R48_HUMAN def: "Taste receptor type 2 member 48" [UniProtKB:P59542] synonym: "T2R48" EXACT [UniProtKB:P59542] xref: EMBL:AAI01805.1 xref: EMBL:AAI11999.1 xref: EMBL:AAM19325.1 xref: EMBL:AAU21141.1 xref: UniProtKB:P59542 xref: UniProtKB:Q3MIJ4 xref: UniProtKB:Q645X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020107 ! TAS2R48_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0071073 ! T2R48_HUMAN-Phosphoserine114 [Term] id: CCO:B0055586 name: T2R49_HUMAN def: "Taste receptor type 2 member 49" [UniProtKB:P59543] synonym: "T2R49" EXACT [UniProtKB:P59543] synonym: "T2R56" EXACT [UniProtKB:P59543] xref: EMBL:AAI00916.1 xref: EMBL:AAI00917.1 xref: EMBL:AAI00919.1 xref: EMBL:AAM19327.1 xref: EMBL:AAM63542.1 xref: EMBL:AAU21140.1 xref: UniProtKB:P59543 xref: UniProtKB:P59549 xref: UniProtKB:Q496D8 xref: UniProtKB:Q645X9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020108 ! TAS2R49_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055587 name: T2R50_HUMAN def: "Taste receptor type 2 member 50" [UniProtKB:P59544] synonym: "T2R50" EXACT [UniProtKB:P59544] synonym: "T2R51" EXACT [UniProtKB:P59544] xref: EMBL:AAI12101.1 xref: EMBL:AAM19326.1 xref: EMBL:AAM63538.1 xref: EMBL:AAU21139.1 xref: UniProtKB:P59544 xref: UniProtKB:P59545 xref: UniProtKB:Q2M255 xref: UniProtKB:Q645Y0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020109 ! TAS2R50_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055588 name: T2R60_HUMAN def: "Taste receptor type 2 member 60" [UniProtKB:P59551] synonym: "T2R56" EXACT [UniProtKB:P59551] synonym: "T2R60" EXACT [UniProtKB:P59551] xref: EMBL:AAI00939.1 xref: EMBL:AAI00940.1 xref: EMBL:AAI00941.1 xref: EMBL:AAM63544.1 xref: EMBL:AAU21151.1 xref: EMBL:DAA01207.1 xref: UniProtKB:P59551 xref: UniProtKB:Q645W8 xref: UniProtKB:Q7RTR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020110 ! TAS2R60_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055589 name: GBG2_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor" [UniProtKB:P59768] synonym: "G gamma-I" EXACT [UniProtKB:P59768] xref: EMBL:AAH20774.1 xref: EMBL:AAH60856.1 xref: EMBL:AAM12584.1 xref: UniProtKB:P59768 xref: UniProtKB:Q6P9A9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017885 ! GNG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066400 ! GBG2_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0066401 ! GBG2_HUMAN-Phosphothreonine52 [Term] id: CCO:B0055590 name: Z280A_HUMAN def: "Zinc finger protein 280A" [UniProtKB:P59817] synonym: "3'OY11.1" EXACT [UniProtKB:P59817] synonym: "Suppressor of hairy wing homolog 1" EXACT [UniProtKB:P59817] xref: EMBL:AAH53901.1 xref: EMBL:BAA20006.1 xref: EMBL:BAA20008.1 xref: UniProtKB:P59817 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020514 ! ZNF280A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055591 name: DCDC1_HUMAN def: "Doublecortin domain-containing protein 1" [UniProtKB:P59894] xref: EMBL:AAP75563.1 xref: EMBL:CAO03494.1 xref: EMBL:CAO03548.1 xref: UniProtKB:A6PVL6 xref: UniProtKB:P59894 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017530 ! DCDC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055592 name: OR2B8_HUMAN def: "Putative olfactory receptor 2B8" [UniProtKB:P59922] synonym: "Hs6M1-29P" EXACT [UniProtKB:P59922] xref: UniProtKB:P59922 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019087 ! OR2B8P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055593 name: ZN445_HUMAN def: "Zinc finger protein 445" [UniProtKB:P59923] synonym: "Zinc finger protein 168" EXACT [UniProtKB:P59923] synonym: "Zinc finger protein with KRAB and SCAN domains 15" EXACT [UniProtKB:P59923] xref: EMBL:AAI01487.1 xref: EMBL:AAP36990.1 xref: EMBL:AAP50258.1 xref: UniProtKB:P59923 xref: UniProtKB:Q3MJD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020756 ! ZNF445_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055594 name: ELOF1_HUMAN def: "Transcription elongation factor 1 homolog" [UniProtKB:P60002] xref: EMBL:AAH07516.1 xref: UniProtKB:P60002 xref: UniProtKB:Q8R1J7 xref: UniProtKB:Q96II4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017696 ! ELOF1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019915 ! atp5c1-u222 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055595 name: DEFB1_HUMAN def: "Beta-defensin 1 precursor" [UniProtKB:P60022] synonym: "BD-1" EXACT [UniProtKB:P60022] synonym: "Defensin, beta 1" EXACT [UniProtKB:P60022] synonym: "hBD-1" EXACT [UniProtKB:P60022] xref: EMBL:AAB49758.1 xref: EMBL:AAC51728.1 xref: EMBL:AAH33298.1 xref: EMBL:AAH47677.1 xref: EMBL:CAA63405.1 xref: EMBL:CAA90650.1 xref: UniProtKB:P60022 xref: UniProtKB:Q09753 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022181 ! DEFB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055596 name: NANO2_HUMAN def: "Nanos homolog 2" [UniProtKB:P60321] xref: EMBL:AAH42883.1 xref: EMBL:AAI17485.1 xref: EMBL:AAI17487.1 xref: UniProtKB:P60321 xref: UniProtKB:Q17R30 xref: UniProtKB:Q4G0P8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018716 ! NANOS2_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0055597 name: NANO3_HUMAN def: "Nanos homolog 3" [UniProtKB:P60323] xref: UniProtKB:P60323 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018717 ! NANOS3_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0055598 name: SNP25_HUMAN def: "Synaptosomal-associated protein 25" [UniProtKB:P60880] synonym: "SNAP-25" EXACT [UniProtKB:P60880] synonym: "SUP" EXACT [UniProtKB:P60880] synonym: "Super protein" EXACT [UniProtKB:P60880] synonym: "Synaptosomal-associated 25 kDa protein" EXACT [UniProtKB:P60880] xref: EMBL:AAC37545.1 xref: EMBL:AAC37546.1 xref: EMBL:AAH10647.1 xref: EMBL:BAA22370.1 xref: EMBL:CAB42860.1 xref: EMBL:CAC34534.1 xref: EMBL:CAD56158.1 xref: UniProtKB:P13795 xref: UniProtKB:P36974 xref: UniProtKB:P60880 xref: UniProtKB:P70557 xref: UniProtKB:P70558 xref: UniProtKB:Q8IXK3 xref: UniProtKB:Q96FM2 xref: UniProtKB:Q9BR45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019963 ! SNAP25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015256 ! snap25-stx11-1 physical interaction relationship: participates_in CCO:I0017791 ! cplx1-snap25-1 physical interaction relationship: participates_in CCO:I0018035 ! hip14-snap25-1 palmitoylation relationship: participates_in CCO:I0018036 ! hip14-snap25-2 palmitoylation relationship: participates_in CCO:I0018494 ! hip14-snap25-3 colocalization relationship: participates_in CCO:I0019625 ! snap25-stx1a physical interaction relationship: participates_in CCO:I0019626 ! stx1a-snap25 physical interaction relationship: participates_in CCO:I0019837 ! snap25-stx11 physical interaction relationship: participates_in CCO:I0020455 ! snap25-loc112476 physical interaction relationship: participates_in CCO:P0002956 ! regulation of insulin secretion relationship: transforms_into CCO:B0070688 ! SNP25_HUMAN-Phosphothreonine138 relationship: transforms_into CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 [Term] id: CCO:B0055599 name: GPR85_HUMAN def: "Probable G-protein coupled receptor 85" [UniProtKB:P60893] synonym: "Super conserved receptor expressed in brain 2" EXACT [UniProtKB:P60893] xref: EMBL:AAF79956.1 xref: EMBL:AAQ93365.1 xref: EMBL:BAA96646.1 xref: EMBL:BAC05911.1 xref: EMBL:CAB82307.1 xref: UniProtKB:P60893 xref: UniProtKB:Q9JHI6 xref: UniProtKB:Q9NPD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018037 ! GPR85_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055600 name: S10AA_HUMAN def: "Protein S100-A10" [UniProtKB:P60903] synonym: "Calpactin I light chain" EXACT [UniProtKB:P60903] synonym: "Calpactin-1 light chain" EXACT [UniProtKB:P60903] synonym: "Cellular ligand of annexin II" EXACT [UniProtKB:P60903] synonym: "p10 protein" EXACT [UniProtKB:P60903] synonym: "p11" EXACT [UniProtKB:P60903] synonym: "S100 calcium-binding protein A10" EXACT [UniProtKB:P60903] xref: EMBL:AAA58404.1 xref: EMBL:AAA58426.1 xref: EMBL:AAH15973.1 xref: EMBL:AAI05787.1 xref: EMBL:CAI12164.1 xref: UniProtKB:P08206 xref: UniProtKB:P60903 xref: UniProtKB:Q5T1C5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019819 ! S100A10_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020158 ! s100a10-setdb1 physical interaction relationship: participates_in CCO:I0020446 ! s100a10-cops6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070273 ! S10AA_HUMAN-Phosphotyrosine25 [Term] id: CCO:B0055601 name: RAB4B_HUMAN def: "Ras-related protein Rab-4B" [UniProtKB:P61018] xref: EMBL:AAD45923.1 xref: EMBL:AAG17228.1 xref: EMBL:AAH46927.1 xref: EMBL:AAM21083.1 xref: EMBL:AAP97171.1 xref: UniProtKB:P22750 xref: UniProtKB:P61018 xref: UniProtKB:Q7Z514 xref: UniProtKB:Q9HBR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019601 ! RAB4B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069689 ! RAB4B_HUMAN-Cysteine methyl ester213 [Term] id: CCO:B0055602 name: RAB2A_HUMAN def: "Ras-related protein Rab-2A" [UniProtKB:P61019] xref: EMBL:AAA60241.1 xref: EMBL:AAH08929.1 xref: EMBL:AAM21078.1 xref: EMBL:AAV38501.1 xref: EMBL:CAA31411.1 xref: UniProtKB:P08886 xref: UniProtKB:P61019 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019585 ! RAB2A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001534 ! ER-Golgi intermediate compartment membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0015807 ! mgc39520-rab2 physical interaction relationship: participates_in CCO:I0015832 ! golga2-rab2 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055603 name: CXCR4_HUMAN def: "C-X-C chemokine receptor type 4" [UniProtKB:P61073] synonym: "CD184 antigen" EXACT [UniProtKB:P61073] synonym: "CXC-R4" EXACT [UniProtKB:P61073] synonym: "CXCR-4" EXACT [UniProtKB:P61073] synonym: "FB22" EXACT [UniProtKB:P61073] synonym: "Fusin" EXACT [UniProtKB:P61073] synonym: "HM89" EXACT [UniProtKB:P61073] synonym: "LCR1" EXACT [UniProtKB:P61073] synonym: "LESTR" EXACT [UniProtKB:P61073] synonym: "Leukocyte-derived seven transmembrane domain receptor" EXACT [UniProtKB:P61073] synonym: "NPYRL" EXACT [UniProtKB:P61073] synonym: "SDF-1 receptor" EXACT [UniProtKB:P61073] synonym: "Stromal cell-derived factor 1 receptor" EXACT [UniProtKB:P61073] xref: EMBL:AAA03209.1 xref: EMBL:AAA16594.1 xref: EMBL:AAA16617.1 xref: EMBL:AAB81970.1 xref: EMBL:AAB93982.1 xref: EMBL:AAC34581.1 xref: EMBL:AAF00130.1 xref: EMBL:AAH20968.1 xref: EMBL:AAO92296.1 xref: EMBL:AAP35306.1 xref: EMBL:AAU05775.1 xref: EMBL:BAA01722.1 xref: EMBL:CAA12166.1 xref: EMBL:CAA50641.1 xref: EMBL:CAA75034.1 xref: UniProtKB:O60835 xref: UniProtKB:P30991 xref: UniProtKB:P56438 xref: UniProtKB:P61073 xref: UniProtKB:Q9UKN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017500 ! CXCR4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015909 ! ccr5-cxcr4-1 colocalization relationship: participates_in CCO:I0016205 ! cxcr4-myh9-2 physical interaction relationship: participates_in CCO:I0016206 ! cxcr4-myh9-4 physical interaction relationship: participates_in CCO:I0017795 ! cxcr4-myh9-1 physical interaction relationship: participates_in CCO:I0017962 ! cxcr4-myh9-3 physical interaction relationship: participates_in CCO:I0017963 ! cxcr4-myh9-5 colocalization relationship: participates_in CCO:I0018486 ! ccr5-cxcr4-2 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0002039 ! T cell proliferation relationship: transforms_into CCO:B0064601 ! CXCR4_HUMAN-Sulfotyrosine21 relationship: transforms_into CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0064603 ! CXCR4_HUMAN-Phosphoserine348 relationship: transforms_into CCO:B0064604 ! CXCR4_HUMAN-Phosphoserine351 [Term] id: CCO:B0055604 name: RAB14_HUMAN def: "Ras-related protein Rab-14" [UniProtKB:P61106] xref: EMBL:AAF00150.1 xref: EMBL:AAF17194.1 xref: EMBL:AAF19400.1 xref: EMBL:AAH06081.1 xref: EMBL:AAM21097.1 xref: EMBL:AAS64573.1 xref: EMBL:BAB14598.1 xref: EMBL:CAB82414.1 xref: EMBL:CAD20124.1 xref: EMBL:CAG33675.1 xref: EMBL:CAI12361.1 xref: UniProtKB:P35287 xref: UniProtKB:P61106 xref: UniProtKB:Q5JVD4 xref: UniProtKB:Q6Q7K5 xref: UniProtKB:Q969L0 xref: UniProtKB:Q9UI11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019572 ! RAB14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069666 ! RAB14_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: transforms_into CCO:B0069668 ! RAB14_HUMAN-Phosphotyrosine99 relationship: transforms_into CCO:B0069669 ! RAB14_HUMAN-Cysteine methyl ester215 [Term] id: CCO:B0055605 name: CSN2_HUMAN def: "COP9 signalosome complex subunit 2" [UniProtKB:P61201] synonym: "Alien homolog" EXACT [UniProtKB:P61201] synonym: "JAB1-containing signalosome subunit 2" EXACT [UniProtKB:P61201] synonym: "SGN2" EXACT [UniProtKB:P61201] synonym: "Signalosome subunit 2" EXACT [UniProtKB:P61201] synonym: "Thyroid receptor-interacting protein 15" EXACT [UniProtKB:P61201] synonym: "TRIP-15" EXACT [UniProtKB:P61201] xref: EMBL:AAC34122.1 xref: EMBL:AAC41734.1 xref: EMBL:AAD30269.1 xref: EMBL:AAD43026.1 xref: EMBL:AAH12629.1 xref: EMBL:AAK26250.1 xref: EMBL:CAG46860.1 xref: UniProtKB:O88950 xref: UniProtKB:P61201 xref: UniProtKB:Q15647 xref: UniProtKB:Q6FGP4 xref: UniProtKB:Q9BY54 xref: UniProtKB:Q9R249 xref: UniProtKB:Q9UNI2 xref: UniProtKB:Q9UNQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017480 ! COPS2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000530 ! signalosome relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055606 name: RPAB2_HUMAN def: "DNA-directed RNA polymerases I, II, and III subunit RPABC2" [UniProtKB:P61218] synonym: "DNA-directed RNA polymerase II subunit F" EXACT [UniProtKB:P61218] synonym: "DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide" EXACT [UniProtKB:P61218] synonym: "RNA polymerases I, II, and III subunit ABC2" EXACT [UniProtKB:P61218] synonym: "RPABC14.4" EXACT [UniProtKB:P61218] synonym: "RPB14.4" EXACT [UniProtKB:P61218] synonym: "RPB6" EXACT [UniProtKB:P61218] synonym: "RPC15" EXACT [UniProtKB:P61218] xref: EMBL:AAH03582.1 xref: EMBL:CAA81629.1 xref: EMBL:CAB62981.1 xref: EMBL:CAG30432.1 xref: UniProtKB:P41584 xref: UniProtKB:P61218 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019777 ! POLR2F_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070150 ! RPAB2_HUMAN-Phosphoserine2 [Term] id: CCO:B0055607 name: SMS_HUMAN def: "Somatostatin precursor" [UniProtKB:P61278] synonym: "Growth hormone release-inhibiting factor" EXACT [UniProtKB:P61278] xref: EMBL:AAA60566.1 xref: EMBL:AAH32625.1 xref: UniProtKB:P01166 xref: UniProtKB:P61278 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019955 ! SST_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0000835 ! induction of apoptosis by hormones relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0055608 name: HAND2_HUMAN def: "Heart- and neural crest derivatives-expressed protein 2" [UniProtKB:P61296] synonym: "Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2" EXACT [UniProtKB:P61296] synonym: "dHAND" EXACT [UniProtKB:P61296] xref: EMBL:AAD13185.1 xref: EMBL:AAD13186.1 xref: UniProtKB:O95300 xref: UniProtKB:O95301 xref: UniProtKB:P61296 xref: UniProtKB:P97833 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018103 ! HAND2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055609 name: OSTN_HUMAN def: "Osteocrin precursor" [UniProtKB:P61366] synonym: "Musclin" EXACT [UniProtKB:P61366] xref: EMBL:AAQ94966.1 xref: EMBL:AAS87599.1 xref: UniProtKB:P61366 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019245 ! OSTN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002482 ! negative regulation of osteoblast differentiation relationship: transforms_into CCO:B0069004 ! OSTN_HUMAN-Arginine amide132 [Term] id: CCO:B0055610 name: ISL1_HUMAN def: "Insulin gene enhancer protein ISL-1" [UniProtKB:P61371] synonym: "Islet-1" EXACT [UniProtKB:P61371] xref: EMBL:AAA81946.1 xref: EMBL:AAD14064.1 xref: EMBL:AAH31213.1 xref: UniProtKB:P20663 xref: UniProtKB:P47894 xref: UniProtKB:P61371 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018326 ! ISL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0067155 ! ISL1_HUMAN-Phosphothreonine182 [Term] id: CCO:B0055611 name: PHS_HUMAN def: "Pterin-4-alpha-carbinolamine dehydratase" [UniProtKB:P61457] synonym: "4-alpha-hydroxy-tetrahydropterin dehydratase" EXACT [UniProtKB:P61457] synonym: "DCoH" EXACT [UniProtKB:P61457] synonym: "Dimerization cofactor of hepatocyte nuclear factor 1-alpha" EXACT [UniProtKB:P61457] synonym: "Dimerization cofactor of HNF1" EXACT [UniProtKB:P61457] synonym: "EC 4.2.1.96" EXACT [UniProtKB:P61457] synonym: "PCD" EXACT [UniProtKB:P61457] synonym: "Phenylalanine hydroxylase-stimulating protein" EXACT [UniProtKB:P61457] synonym: "PHS" EXACT [UniProtKB:P61457] synonym: "Pterin carbinolamine dehydratase" EXACT [UniProtKB:P61457] xref: EMBL:AAA69662.1 xref: EMBL:AAA69663.1 xref: EMBL:AAD25732.1 xref: EMBL:AAH06324.1 xref: UniProtKB:P61457 xref: UniProtKB:P70519 xref: UniProtKB:P80095 xref: UniProtKB:Q9D930 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019386 ! PCBD1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000902 ! phenylalanine 4-monooxygenase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001729 ! 4-alpha-hydroxytetrahydrobiopterin dehydratase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0014984 ! dvl2-pcbd1 physical interaction relationship: participates_in CCO:I0014993 ! pcbd1-pcbd1 physical interaction relationship: participates_in CCO:I0015383 ! lnx-pcbd1 physical interaction relationship: participates_in CCO:I0015603 ! gorasp2-pcbd1 physical interaction relationship: participates_in CCO:I0015703 ! nif3l1-pcbd1 physical interaction relationship: participates_in CCO:I0015785 ! c8orf32-pcbd1 physical interaction relationship: participates_in CCO:I0019417 ! pcbd1-pcbd1-1 physical interaction relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0069290 ! PHS_HUMAN-N-acetylalanine2 [Term] id: CCO:B0055612 name: DAD1_HUMAN def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1" [UniProtKB:P61803] synonym: "DAD-1" EXACT [UniProtKB:P61803] synonym: "Defender against cell death 1" EXACT [UniProtKB:P61803] synonym: "EC 2.4.1.119" EXACT [UniProtKB:P61803] synonym: "Oligosaccharyl transferase subunit DAD1" EXACT [UniProtKB:P61803] xref: EMBL:AAB58540.1 xref: EMBL:AAH07403.1 xref: EMBL:AAH09798.1 xref: EMBL:AAO74827.1 xref: EMBL:BAA03650.1 xref: EMBL:CAG28610.1 xref: EMBL:CAG47001.1 xref: UniProtKB:O08552 xref: UniProtKB:O70364 xref: UniProtKB:P46966 xref: UniProtKB:P46968 xref: UniProtKB:P61803 xref: UniProtKB:Q6FGA3 xref: UniProtKB:Q96GB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017520 ! DAD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0064624 ! DAD1_HUMAN-N-acetylserine2 [Term] id: CCO:B0055613 name: NPC2_HUMAN def: "Epididymal secretory protein E1 precursor" [UniProtKB:P61916] synonym: "hE1" EXACT [UniProtKB:P61916] synonym: "Niemann-Pick disease type C2 protein" EXACT [UniProtKB:P61916] xref: EMBL:AAH02532.1 xref: EMBL:CAA47928.1 xref: UniProtKB:P61916 xref: UniProtKB:Q15668 xref: UniProtKB:Q29413 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018831 ! NPC2_human relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:P0001146 ! regulation of isoprenoid metabolic process [Term] id: CCO:B0055614 name: GBG11_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 precursor" [UniProtKB:P61952] xref: EMBL:AAC50206.1 xref: EMBL:AAH09709.1 xref: EMBL:AAM12592.1 xref: EMBL:AAS02020.1 xref: UniProtKB:P50152 xref: UniProtKB:P61952 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017881 ! GNG11_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015520 ! amotl2-gng11 physical interaction relationship: participates_in CCO:I0020325 ! gng11-zhx1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0055615 name: BTG1_HUMAN def: "Protein BTG1" [UniProtKB:P62324] synonym: "B-cell translocation gene 1 protein" EXACT [UniProtKB:P62324] xref: EMBL:AAH16759.1 xref: EMBL:AAH64953.1 xref: EMBL:AAV38643.1 xref: EMBL:AAV97814.1 xref: EMBL:CAA43435.1 xref: UniProtKB:P31607 xref: UniProtKB:P62324 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017188 ! BTG1_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004209 ! kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015035 ! btg1-cnot8 physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002417 ! positive regulation of endothelial cell differentiation relationship: participates_in CCO:P0002477 ! positive regulation of myoblast differentiation [Term] id: CCO:B0055616 name: ARF6_HUMAN def: "ADP-ribosylation factor 6" [UniProtKB:P62330] xref: EMBL:AAA90928.1 xref: EMBL:AAC39877.1 xref: EMBL:AAH08918.1 xref: EMBL:AAM12599.1 xref: UniProtKB:P26438 xref: UniProtKB:P62330 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017007 ! ARF6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000489 ! cell cortex relationship: participates_in CCO:I0017772 ! arf6-atp6v1c1-5 physical interaction relationship: participates_in CCO:I0017947 ! arf6-atp6v1c1-6 physical interaction relationship: participates_in CCO:I0018506 ! arf6-arfip2-1 physical interaction relationship: participates_in CCO:I0018652 ! arf6-arfip2-3 physical interaction relationship: participates_in CCO:I0018661 ! arf6-arfip2-2 physical interaction relationship: participates_in CCO:I0018663 ! arfip2-arf6-3 physical interaction relationship: participates_in CCO:I0018882 ! arf6-atp6v1c1-2 physical interaction relationship: participates_in CCO:I0019520 ! arf6-atp6v1c1-4 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001331 ! positive regulation of actin filament polymerization relationship: participates_in CCO:P0001982 ! regulation of Rac protein signal transduction relationship: participates_in CCO:P0002803 ! negative regulation of receptor-mediated endocytosis [Term] id: CCO:B0055617 name: SELT_HUMAN def: "Selenoprotein T precursor" [UniProtKB:P62341] synonym: "SelT" EXACT [UniProtKB:P62341] xref: EMBL:AAD20063.1 xref: EMBL:AAF13696.1 xref: EMBL:AAH06012.2 xref: EMBL:AAH08411.2 xref: EMBL:AAH09556.2 xref: EMBL:AAH09611.2 xref: EMBL:AAH26350.2 xref: EMBL:AAH36738.3 xref: EMBL:AAH71699.1 xref: EMBL:AAQ88462.1 xref: EMBL:AAQ88463.1 xref: UniProtKB:O95904 xref: UniProtKB:P62341 xref: UniProtKB:Q8IY80 xref: UniProtKB:Q9CZ45 xref: UniProtKB:Q9NZJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019865 ! SELT_human relationship: has_function CCO:F0001897 ! selenium binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020329 ! hbb-selt physical interaction relationship: participates_in CCO:P0000465 ! selenocysteine incorporation [Term] id: CCO:B0055618 name: TBPL1_HUMAN def: "TATA box-binding protein-like protein 1" [UniProtKB:P62380] synonym: "21 kDa TBP-like protein" EXACT [UniProtKB:P62380] synonym: "STUD protein" EXACT [UniProtKB:P62380] synonym: "TATA box-binding protein-related factor 2" EXACT [UniProtKB:P62380] synonym: "TBP-like protein 1" EXACT [UniProtKB:P62380] synonym: "TBP-related factor 2" EXACT [UniProtKB:P62380] xref: EMBL:AAD24800.1 xref: EMBL:AAD28785.1 xref: EMBL:AAH00381.1 xref: EMBL:AAH17559.1 xref: EMBL:BAA75218.1 xref: EMBL:CAB43704.1 xref: UniProtKB:O95753 xref: UniProtKB:P62380 xref: UniProtKB:Q9BWD5 xref: UniProtKB:Q9Z2Z0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020190 ! TBPL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020082 ! ndufa6-tbpl1 physical interaction relationship: participates_in CCO:I0020428 ! rab35-tbpl1 physical interaction relationship: participates_in CCO:I0020441 ! rpl10-tbpl1 physical interaction relationship: participates_in CCO:I0020558 ! flj20758-tbpl1 physical interaction relationship: participates_in CCO:I0020577 ! irak4-tbpl1 physical interaction relationship: participates_in CCO:I0020587 ! m6prbp1-tbpl1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055619 name: ERF1_HUMAN def: "Eukaryotic peptide chain release factor subunit 1" [UniProtKB:P62495] synonym: "eRF1" EXACT [UniProtKB:P62495] synonym: "Eukaryotic release factor 1" EXACT [UniProtKB:P62495] synonym: "Protein Cl1" EXACT [UniProtKB:P62495] synonym: "TB3-1" EXACT [UniProtKB:P62495] xref: EMBL:AAA36665.1 xref: EMBL:AAB49726.1 xref: EMBL:AAD43966.1 xref: EMBL:AAH88358.1 xref: EMBL:CAA57281.1 xref: UniProtKB:P46055 xref: UniProtKB:P62495 xref: UniProtKB:Q5M7Z7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017726 ! ETF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000664 ! regulation of translational termination relationship: transforms_into CCO:B0065121 ! ERF1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0055620 name: CNBP_HUMAN def: "Cellular nucleic acid-binding protein" [UniProtKB:P62633] synonym: "CNBP" EXACT [UniProtKB:P62633] synonym: "Zinc finger protein 9" EXACT [UniProtKB:P62633] xref: EMBL:AAA61975.1 xref: EMBL:AAA91782.1 xref: EMBL:AAH00288.1 xref: EMBL:AAH14911.1 xref: EMBL:AAH93058.1 xref: EMBL:AAR89462.1 xref: EMBL:BAB70769.1 xref: UniProtKB:P20694 xref: UniProtKB:P62633 xref: UniProtKB:Q5QJR0 xref: UniProtKB:Q6PJI7 xref: UniProtKB:Q96NV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017398 ! CNBP_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055621 name: GBB1_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1" [UniProtKB:P62873] synonym: "Transducin beta chain 1" EXACT [UniProtKB:P62873] xref: EMBL:AAA63265.1 xref: EMBL:AAH04186.1 xref: EMBL:AAH05888.1 xref: EMBL:AAH08991.1 xref: EMBL:AAM15918.1 xref: EMBL:AAP35969.1 xref: EMBL:CAA28207.1 xref: EMBL:CAG33065.1 xref: EMBL:CAI20029.1 xref: EMBL:CAI95654.1 xref: EMBL:EAW56147.1 xref: UniProtKB:B1AJZ7 xref: UniProtKB:P04697 xref: UniProtKB:P04901 xref: UniProtKB:P62873 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017876 ! GNB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0016713 ! map3k3-gnb1 physical interaction relationship: participates_in CCO:I0017431 ! disc1-gnb1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000748 ! acetylcholine receptor signaling, muscarinic pathway relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066388 ! GBB1_HUMAN-N-acetylserine2 [Term] id: CCO:B0055622 name: RPAB5_HUMAN def: "DNA-directed RNA polymerases I, II, and III subunit RPABC5" [UniProtKB:P62875] synonym: "DNA-directed RNA polymerase II 7.6 kDa polypeptide" EXACT [UniProtKB:P62875] synonym: "DNA-directed RNA polymerase III subunit L" EXACT [UniProtKB:P62875] synonym: "RNA polymerases I, II, and III subunit ABC5" EXACT [UniProtKB:P62875] synonym: "RPB10" EXACT [UniProtKB:P62875] synonym: "RPB7.6" EXACT [UniProtKB:P62875] xref: EMBL:AAA91459.1 xref: EMBL:AAH05903.1 xref: EMBL:AAH18649.1 xref: EMBL:CAA87657.1 xref: EMBL:CAA87658.1 xref: UniProtKB:P52436 xref: UniProtKB:P62875 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019779 ! POLR2L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0017182 ! nfkbib-polr2l physical interaction relationship: participates_in CCO:P0000656 ! regulation of transcription from RNA polymerase I promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055623 name: GBB2_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2" [UniProtKB:P62879] synonym: "G protein subunit beta-2" EXACT [UniProtKB:P62879] synonym: "Transducin beta chain 2" EXACT [UniProtKB:P62879] xref: EMBL:AAA03179.1 xref: EMBL:AAA35922.1 xref: EMBL:AAA63264.1 xref: EMBL:AAC78794.1 xref: EMBL:AAH10073.1 xref: EMBL:AAH12348.1 xref: EMBL:AAH68003.1 xref: EMBL:AAM15919.1 xref: UniProtKB:P11016 xref: UniProtKB:P54312 xref: UniProtKB:P62879 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017877 ! GNB2_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001514 ! calcium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0016667 ! map3k3-gnb2 physical interaction relationship: participates_in CCO:I0020011 ! gnb2-capns1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066389 ! GBB2_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066390 ! GBB2_HUMAN-Phosphotyrosine239 [Term] id: CCO:B0055624 name: CANB1_HUMAN def: "Calcineurin subunit B type 1" [UniProtKB:P63098] synonym: "Protein phosphatase 2B regulatory subunit 1" EXACT [UniProtKB:P63098] synonym: "Protein phosphatase 3 regulatory subunit B alpha isoform 1" EXACT [UniProtKB:P63098] xref: EMBL:AAB08721.1 xref: EMBL:AAH27913.1 xref: EMBL:AAY14715.1 xref: EMBL:CAG33219.1 xref: UniProtKB:P06705 xref: UniProtKB:P15117 xref: UniProtKB:P63098 xref: UniProtKB:Q08044 xref: UniProtKB:Q53SL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017221 ! PPP3R1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: transforms_into CCO:B0064058 ! CANB1_HUMAN-Phosphotyrosine106 [Term] id: CCO:B0055625 name: POK4_HUMAN def: "HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein" [UniProtKB:P63128] synonym: "HERV-K(C6) Gag-Pol protein" EXACT [UniProtKB:P63128] synonym: "HERV-K109 Gag-Pol protein" EXACT [UniProtKB:P63128] xref: EMBL:AAD51799.1 xref: UniProtKB:P63128 xref: UniProtKB:Q9UKH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000659 ! aspartic-type endopeptidase activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000867 ! viral capsid relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055626 name: POK5_HUMAN def: "HERV-K_19p13.11 provirus ancestral Pol protein" [UniProtKB:P63132] synonym: "HERV-K113 Pol protein" EXACT [UniProtKB:P63132] xref: UniProtKB:P63132 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055627 name: POK6_HUMAN def: "HERV-K_8p23.1 provirus ancestral Pol protein" [UniProtKB:P63133] synonym: "HERV-K115 Pol protein" EXACT [UniProtKB:P63133] xref: UniProtKB:P63133 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055628 name: POK9_HUMAN def: "HERV-K_5q13.3 provirus ancestral Pol protein" [UniProtKB:P63134] synonym: "HERV-K104 Pol protein" EXACT [UniProtKB:P63134] xref: UniProtKB:P63134 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055629 name: POK12_HUMAN def: "HERV-K_1q22 provirus ancestral Pol protein" [UniProtKB:P63135] synonym: "HERV-K(III) Pol protein" EXACT [UniProtKB:P63135] synonym: "HERV-K102 Pol protein" EXACT [UniProtKB:P63135] xref: UniProtKB:P63135 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000867 ! viral capsid relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055630 name: POK17_HUMAN def: "HERV-K_11q22.1 provirus ancestral Pol protein" [UniProtKB:P63136] xref: UniProtKB:P63136 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055631 name: GBG1_HUMAN def: "Guanine nucleotide-binding protein G(T) subunit gamma-T1 precursor" [UniProtKB:P63211] synonym: "Transducin gamma chain" EXACT [UniProtKB:P63211] xref: EMBL:AAB26896.1 xref: EMBL:AAB92386.1 xref: EMBL:AAD13931.1 xref: EMBL:AAH29367.1 xref: EMBL:AAM12583.1 xref: EMBL:AAS02021.1 xref: EMBL:CAG33193.1 xref: UniProtKB:O43835 xref: UniProtKB:P63211 xref: UniProtKB:Q08447 xref: UniProtKB:Q16026 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017884 ! GNGT1_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055632 name: GBG3_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 precursor" [UniProtKB:P63215] xref: EMBL:AAD40371.1 xref: EMBL:AAF04567.1 xref: EMBL:AAH15563.1 xref: EMBL:AAM12585.1 xref: EMBL:AAP97199.1 xref: UniProtKB:P29798 xref: UniProtKB:P63215 xref: UniProtKB:Q61014 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017886 ! GNG3_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066402 ! GBG3_HUMAN-Phosphothreonine5 relationship: transforms_into CCO:B0066403 ! GBG3_HUMAN-Phosphoserine9 [Term] id: CCO:B0055633 name: GBG5_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 precursor" [UniProtKB:P63218] xref: EMBL:AAC39869.1 xref: EMBL:AAC72203.1 xref: EMBL:AAH03563.1 xref: EMBL:AAM12587.1 xref: EMBL:AAP35469.1 xref: EMBL:CAH70203.1 xref: UniProtKB:P30670 xref: UniProtKB:P63218 xref: UniProtKB:Q5VX54 xref: UniProtKB:Q61015 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017888 ! GNG5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0055634 name: TNNC1_HUMAN def: "Troponin C, slow skeletal and cardiac muscles" [UniProtKB:P63316] synonym: "TN-C" EXACT [UniProtKB:P63316] xref: EMBL:AAA36772.1 xref: EMBL:AAB91994.1 xref: EMBL:AAH30244.1 xref: EMBL:CAA30736.1 xref: UniProtKB:O14800 xref: UniProtKB:P02590 xref: UniProtKB:P04463 xref: UniProtKB:P63316 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020308 ! TNNC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001746 ! regulation of muscle filament sliding speed relationship: transforms_into CCO:B0071441 ! TNNC1_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0055635 name: HBB_HUMAN def: "Hemoglobin subunit beta" [UniProtKB:P68871] synonym: "Beta-globin" EXACT [UniProtKB:P68871] synonym: "Hemoglobin beta chain" EXACT [UniProtKB:P68871] xref: EMBL:AAA16334.1 xref: EMBL:AAA21100.1 xref: EMBL:AAA21101.1 xref: EMBL:AAA21102.1 xref: EMBL:AAA21103.1 xref: EMBL:AAA21104.1 xref: EMBL:AAA21105.1 xref: EMBL:AAA21106.1 xref: EMBL:AAA21107.1 xref: EMBL:AAA21108.1 xref: EMBL:AAA21109.1 xref: EMBL:AAA21110.1 xref: EMBL:AAA21111.1 xref: EMBL:AAA21112.1 xref: EMBL:AAA21113.1 xref: EMBL:AAA21114.1 xref: EMBL:AAA21115.1 xref: EMBL:AAA21116.1 xref: EMBL:AAA35597.1 xref: EMBL:AAA35966.1 xref: EMBL:AAA52633.1 xref: EMBL:AAA52634.1 xref: EMBL:AAA88054.1 xref: EMBL:AAA88059.1 xref: EMBL:AAA88061.1 xref: EMBL:AAA88063.1 xref: EMBL:AAA88065.1 xref: EMBL:AAA88067.1 xref: EMBL:AAB62944.1 xref: EMBL:AAD19696.1 xref: EMBL:AAF00489.1 xref: EMBL:AAH07075.1 xref: EMBL:AAK29639.1 xref: EMBL:AAM92001.1 xref: EMBL:AAN11320.1 xref: EMBL:AAN84548.1 xref: EMBL:AAP21062.1 xref: EMBL:AAZ39745.1 xref: EMBL:AAZ39746.1 xref: EMBL:AAZ39747.1 xref: EMBL:AAZ39748.1 xref: EMBL:AAZ39749.1 xref: EMBL:AAZ39750.1 xref: EMBL:AAZ39751.1 xref: EMBL:AAZ39752.1 xref: EMBL:AAZ39753.1 xref: EMBL:AAZ39754.1 xref: EMBL:AAZ39755.1 xref: EMBL:AAZ39756.1 xref: EMBL:AAZ39757.1 xref: EMBL:AAZ39758.1 xref: EMBL:AAZ39759.1 xref: EMBL:AAZ39760.1 xref: EMBL:AAZ39761.1 xref: EMBL:AAZ39762.1 xref: EMBL:AAZ39763.1 xref: EMBL:AAZ39764.1 xref: EMBL:AAZ39765.1 xref: EMBL:AAZ39766.1 xref: EMBL:AAZ39767.1 xref: EMBL:AAZ39768.1 xref: EMBL:AAZ39769.1 xref: EMBL:AAZ39770.1 xref: EMBL:AAZ39771.1 xref: EMBL:AAZ39772.1 xref: EMBL:AAZ39773.1 xref: EMBL:AAZ39774.1 xref: EMBL:AAZ39775.1 xref: EMBL:AAZ39776.1 xref: EMBL:AAZ39777.1 xref: EMBL:AAZ39778.1 xref: EMBL:AAZ39779.1 xref: EMBL:AAZ39780.1 xref: EMBL:AAZ39781.1 xref: EMBL:AAZ39782.1 xref: EMBL:AAZ39783.1 xref: EMBL:AAZ39784.1 xref: EMBL:AAZ39785.1 xref: EMBL:AAZ39786.1 xref: EMBL:AAZ39787.1 xref: EMBL:AAZ39788.1 xref: EMBL:AAZ39789.1 xref: EMBL:AAZ39790.1 xref: EMBL:AAZ39791.1 xref: EMBL:AAZ39792.1 xref: EMBL:AAZ39793.1 xref: EMBL:AAZ39794.1 xref: EMBL:AAZ39795.1 xref: EMBL:AAZ39796.1 xref: EMBL:AAZ39797.1 xref: EMBL:AAZ39798.1 xref: EMBL:AAZ39799.1 xref: EMBL:AAZ39800.1 xref: EMBL:CAA00182.1 xref: EMBL:CAA23756.1 xref: EMBL:CAA23758.1 xref: EMBL:CAA23759.1 xref: EMBL:CAG38767.1 xref: EMBL:CAG46711.1 xref: UniProtKB:P02023 xref: UniProtKB:P68871 xref: UniProtKB:Q13852 xref: UniProtKB:Q14481 xref: UniProtKB:Q14510 xref: UniProtKB:Q45KT0 xref: UniProtKB:Q6FI08 xref: UniProtKB:Q8IZI1 xref: UniProtKB:Q9BX96 xref: UniProtKB:Q9UCP8 xref: UniProtKB:Q9UCP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018105 ! HBB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015857 ! hba1-hbb-9 direct interaction relationship: participates_in CCO:I0015859 ! hba1-hbb-13 direct interaction relationship: participates_in CCO:I0015860 ! hba1-hbb-14 direct interaction relationship: participates_in CCO:I0015861 ! hba1-hbb-15 direct interaction relationship: participates_in CCO:I0016198 ! hba1-hbb-16 direct interaction relationship: participates_in CCO:I0016199 ! hba1-hbb-17 direct interaction relationship: participates_in CCO:I0017790 ! hba1-hbb-12 direct interaction relationship: participates_in CCO:I0017950 ! hba1-hbb-10 direct interaction relationship: participates_in CCO:I0017951 ! hba1-hbb-11 direct interaction relationship: participates_in CCO:I0018257 ! hba1-hbb-18 direct interaction relationship: participates_in CCO:I0018710 ! hba1-hbb-8 direct interaction relationship: participates_in CCO:I0018732 ! hba1-hbb-1 direct interaction relationship: participates_in CCO:I0018733 ! hba1-hbb-2 direct interaction relationship: participates_in CCO:I0018734 ! hba1-hbb-3 direct interaction relationship: participates_in CCO:I0018735 ! hba1-hbb-4 direct interaction relationship: participates_in CCO:I0018736 ! hba1-hbb-5 direct interaction relationship: participates_in CCO:I0018737 ! hba1-hbb-6 direct interaction relationship: participates_in CCO:I0018738 ! hba1-hbb-7 direct interaction relationship: participates_in CCO:I0020020 ! hba1-hbb physical interaction relationship: participates_in CCO:I0020329 ! hbb-selt physical interaction relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: transforms_into CCO:B0066760 ! HBB_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0066761 ! HBB_HUMAN-2-iminyl-valine2 relationship: transforms_into CCO:B0066762 ! HBB_HUMAN-S-nitrosocysteine94 relationship: transforms_into CCO:B0066763 ! HBB_HUMAN-Phosphotyrosine131 [Term] id: CCO:B0055636 name: 3BP2_HUMAN def: "SH3 domain-binding protein 2" [UniProtKB:P78314] synonym: "3BP-2" EXACT [UniProtKB:P78314] xref: EMBL:AAB59973.1 xref: EMBL:AAB72034.1 xref: EMBL:AAH22996.1 xref: EMBL:BAA19119.1 xref: EMBL:BAA19120.1 xref: EMBL:EAW82509.1 xref: UniProtKB:A6NNC2 xref: UniProtKB:O00500 xref: UniProtKB:O15373 xref: UniProtKB:P78314 xref: UniProtKB:P78315 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016845 ! SH3BP2_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020663 ! sh3bp2-tf physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065197 ! 3BP2_HUMAN-Phosphoserine278 [Term] id: CCO:B0055637 name: IGBP1_HUMAN def: "Immunoglobulin-binding protein 1" [UniProtKB:P78318] synonym: "B-cell signal transduction molecule alpha 4" EXACT [UniProtKB:P78318] synonym: "CD79a-binding protein 1" EXACT [UniProtKB:P78318] synonym: "Protein alpha-4" EXACT [UniProtKB:P78318] synonym: "Renal carcinoma antigen NY-REN-16" EXACT [UniProtKB:P78318] xref: EMBL:AAH04137.1 xref: EMBL:AAP35382.1 xref: EMBL:CAA70119.1 xref: EMBL:CAD13488.2 xref: UniProtKB:P78318 xref: UniProtKB:Q8TAB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018237 ! IGBP1_human relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0055638 name: PITX1_HUMAN def: "Pituitary homeobox 1" [UniProtKB:P78337] synonym: "Hindlimb-expressed homeobox protein backfoot" EXACT [UniProtKB:P78337] xref: EMBL:AAB65251.1 xref: EMBL:AAC17733.1 xref: EMBL:AAC51126.1 xref: EMBL:AAH03685.1 xref: EMBL:AAH09412.1 xref: UniProtKB:O14677 xref: UniProtKB:O60425 xref: UniProtKB:P78337 xref: UniProtKB:Q9BTI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019402 ! PITX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015403 ! pitx1-rbpms physical interaction relationship: participates_in CCO:I0015526 ! pepp2-pitx1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069313 ! PITX1_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0069314 ! PITX1_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0069315 ! PITX1_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0069316 ! PITX1_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0069317 ! PITX1_HUMAN-Phosphothreonine53 [Term] id: CCO:B0055639 name: ACCN2_HUMAN def: "Amiloride-sensitive cation channel 2, neuronal" [UniProtKB:P78348] synonym: "Acid-sensing ion channel 1" EXACT [UniProtKB:P78348] synonym: "ASIC1" EXACT [UniProtKB:P78348] synonym: "BNaC2" EXACT [UniProtKB:P78348] synonym: "Brain sodium channel 2" EXACT [UniProtKB:P78348] xref: EMBL:AAB48980.1 xref: EMBL:AAB48981.1 xref: EMBL:AAH13891.2 xref: UniProtKB:P78348 xref: UniProtKB:P78349 xref: UniProtKB:Q96CV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016881 ! ACCN2_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001527 ! sodium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002737 ! amiloride-sensitive sodium channel activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016313 ! accn2-prkpcabp-2 physical interaction relationship: participates_in CCO:I0017901 ! accn2-prkcabp-1 physical interaction relationship: participates_in CCO:I0017902 ! accn2-prkcabp-3 colocalization relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065312 ! ACCN2_HUMAN-Phosphoserine479 [Term] id: CCO:B0055640 name: PI42B_HUMAN def: "Phosphatidylinositol-5-phosphate 4-kinase type-2 beta" [UniProtKB:P78356] synonym: "1-phosphatidylinositol-5-phosphate 4-kinase 2-beta" EXACT [UniProtKB:P78356] synonym: "Diphosphoinositide kinase 2-beta" EXACT [UniProtKB:P78356] synonym: "EC 2.7.1.149" EXACT [UniProtKB:P78356] synonym: "Phosphatidylinositol-5-phosphate 4-kinase type II beta" EXACT [UniProtKB:P78356] synonym: "PIP4KII-beta" EXACT [UniProtKB:P78356] synonym: "PtdIns(5)P-4-kinase isoform 2-beta" EXACT [UniProtKB:P78356] xref: EMBL:AAB48596.1 xref: EMBL:AAH27459.1 xref: EMBL:AAV38420.1 xref: UniProtKB:P78356 xref: UniProtKB:Q5U0E8 xref: UniProtKB:Q8TBP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019392 ! PIP4K2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017596 ! ubqln4-pip5k2b-1 physical interaction relationship: participates_in CCO:I0018894 ! ubqln4-pip5k2b physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0069292 ! PI42B_HUMAN-Phosphotyrosine98 [Term] id: CCO:B0055641 name: CNTP1_HUMAN def: "Contactin-associated protein 1 precursor" [UniProtKB:P78357] synonym: "Caspr" EXACT [UniProtKB:P78357] synonym: "Caspr1" EXACT [UniProtKB:P78357] synonym: "Neurexin 4" EXACT [UniProtKB:P78357] synonym: "Neurexin IV" EXACT [UniProtKB:P78357] synonym: "p190" EXACT [UniProtKB:P78357] xref: EMBL:AAB48481.1 xref: UniProtKB:P78357 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017417 ! CNTNAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064430 ! CNTP1_HUMAN-Phosphoserine1383 [Term] id: CCO:B0055642 name: NKX32_HUMAN def: "Homeobox protein Nkx-3.2" [UniProtKB:P78367] synonym: "Bagpipe homeobox protein homolog 1" EXACT [UniProtKB:P78367] synonym: "Homeobox protein NK-3 homolog B" EXACT [UniProtKB:P78367] xref: EMBL:AAB49696.1 xref: EMBL:AAB82783.1 xref: EMBL:AAB82784.1 xref: EMBL:AAC39536.1 xref: EMBL:AAI11967.1 xref: UniProtKB:P78367 xref: UniProtKB:Q2M2I7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018801 ! NKX3-2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055643 name: IRX6_HUMAN def: "Iroquois-class homeodomain protein IRX-6" [UniProtKB:P78412] synonym: "Homeodomain protein IRXB3" EXACT [UniProtKB:P78412] synonym: "Iroquois homeobox protein 6" EXACT [UniProtKB:P78412] xref: EMBL:AAB50003.1 xref: EMBL:AAQ16543.1 xref: EMBL:AAQ16552.1 xref: EMBL:BAC86033.1 xref: UniProtKB:P78412 xref: UniProtKB:Q7Z2K0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018323 ! IRX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055644 name: IRX4_HUMAN def: "Iroquois-class homeodomain protein IRX-4" [UniProtKB:P78413] synonym: "Homeodomain protein IRXA3" EXACT [UniProtKB:P78413] synonym: "Iroquois homeobox protein 4" EXACT [UniProtKB:P78413] xref: EMBL:AAB50004.1 xref: EMBL:AAF23887.1 xref: EMBL:AAQ16547.1 xref: UniProtKB:P78413 xref: UniProtKB:Q9UHR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018321 ! IRX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055645 name: X3CL1_HUMAN def: "Fractalkine precursor" [UniProtKB:P78423] synonym: "C-X3-C motif chemokine 1" EXACT [UniProtKB:P78423] synonym: "CX3C membrane-anchored chemokine" EXACT [UniProtKB:P78423] synonym: "Neurotactin" EXACT [UniProtKB:P78423] synonym: "Small-inducible cytokine D1" EXACT [UniProtKB:P78423] xref: EMBL:AAB49679.1 xref: EMBL:AAB50014.1 xref: EMBL:AAC24307.1 xref: EMBL:AAH01163.1 xref: EMBL:AAH16164.1 xref: UniProtKB:O00672 xref: UniProtKB:P78423 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020504 ! CX3CL1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0003010 ! positive regulation of calcium-independent cell-cell adhesion [Term] id: CCO:B0055646 name: PO6F2_HUMAN def: "POU domain, class 6, transcription factor 2" [UniProtKB:P78424] synonym: "Retina-derived POU domain factor 1" EXACT [UniProtKB:P78424] synonym: "RPF-1" EXACT [UniProtKB:P78424] xref: EMBL:AAB49727.1 xref: EMBL:AAB49728.1 xref: EMBL:AAC83404.2 xref: EMBL:AAP21873.1 xref: EMBL:AAS07475.1 xref: UniProtKB:P78424 xref: UniProtKB:P78425 xref: UniProtKB:Q75ME8 xref: UniProtKB:Q86UM6 xref: UniProtKB:Q9UDS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019464 ! POU6F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055647 name: RELN_HUMAN def: "Reelin precursor" [UniProtKB:P78509] synonym: "EC 3.4.21.-" EXACT [UniProtKB:P78509] xref: EMBL:AAB46357.2 xref: EMBL:AAC51105.1 xref: EMBL:AAD29127.1 xref: EMBL:AAM49151.1 xref: EMBL:AAP22330.1 xref: EMBL:AAP22355.1 xref: UniProtKB:P78509 xref: UniProtKB:Q86UJ0 xref: UniProtKB:Q86UJ8 xref: UniProtKB:Q8NDV0 xref: UniProtKB:Q9UDQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019666 ! RELN_human relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0003019 ! positive regulation of small GTPase mediated signal transduction [Term] id: CCO:B0055648 name: ARGI2_HUMAN def: "Arginase-2, mitochondrial precursor" [UniProtKB:P78540] synonym: "Arginase II" EXACT [UniProtKB:P78540] synonym: "EC 3.5.3.1" EXACT [UniProtKB:P78540] synonym: "Kidney-type arginase" EXACT [UniProtKB:P78540] synonym: "Non-hepatic arginase" EXACT [UniProtKB:P78540] xref: EMBL:AAB39855.1 xref: EMBL:AAC51664.1 xref: EMBL:AAH01350.1 xref: EMBL:AAH08464.1 xref: EMBL:AAH29050.1 xref: EMBL:AAL71548.1 xref: EMBL:BAA13158.1 xref: EMBL:CAG38787.1 xref: UniProtKB:P78540 xref: UniProtKB:Q6FHY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017013 ! ARG2_human relationship: has_function CCO:F0000528 ! arginase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008027 ! nitric-oxide synthase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0002367 ! regulation of nitric oxide biosynthetic process [Term] id: CCO:B0055649 name: BTG2_HUMAN def: "Protein BTG2" [UniProtKB:P78543] synonym: "BTG family member 2" EXACT [UniProtKB:P78543] synonym: "NGF-inducible anti-proliferative protein PC3" EXACT [UniProtKB:P78543] xref: EMBL:AAB37580.1 xref: EMBL:AAI05949.1 xref: EMBL:AAI05950.1 xref: EMBL:AAL05626.1 xref: EMBL:CAA71074.1 xref: EMBL:CAH70451.1 xref: UniProtKB:P78543 xref: UniProtKB:Q3KR25 xref: UniProtKB:Q5VUT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017189 ! BTG2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0055650 name: ELF3_HUMAN def: "ETS-related transcription factor Elf-3" [UniProtKB:P78545] synonym: "E74-like factor 3" EXACT [UniProtKB:P78545] synonym: "Epithelial-restricted with serine box" EXACT [UniProtKB:P78545] synonym: "Epithelium-restricted Ets protein ESX" EXACT [UniProtKB:P78545] synonym: "Epithelium-specific Ets transcription factor 1" EXACT [UniProtKB:P78545] synonym: "ESE-1" EXACT [UniProtKB:P78545] xref: EMBL:AAB58075.1 xref: EMBL:AAB65823.1 xref: EMBL:AAB65824.1 xref: EMBL:AAB67238.1 xref: EMBL:AAB96586.1 xref: EMBL:AAC51884.1 xref: EMBL:AAD45237.1 xref: EMBL:AAH03569.1 xref: EMBL:AAM70481.1 xref: EMBL:CAD29859.1 xref: EMBL:CAD97611.1 xref: EMBL:CAG33387.1 xref: EMBL:CAI14961.1 xref: UniProtKB:P78545 xref: UniProtKB:Q6IAP8 xref: UniProtKB:Q7RU03 xref: UniProtKB:Q7Z3X2 xref: UniProtKB:Q8NFG2 xref: UniProtKB:Q99718 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017683 ! ELF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055651 name: P78548_HUMAN def: "G18 (Putative uncharacterized protein) (HCG2001537, isoform CRA_f)" [UniProtKB:P78548] xref: EMBL:AAB47489.1 xref: EMBL:AAC63096.1 xref: EMBL:EAX03617.1 xref: UniProtKB:P78548 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021080 ! hCG_2001537_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055652 name: I13R1_HUMAN def: "Interleukin-13 receptor alpha-1 chain precursor" [UniProtKB:P78552] synonym: "Cancer/testis antigen 19" EXACT [UniProtKB:P78552] synonym: "CD213a1 antigen" EXACT [UniProtKB:P78552] synonym: "CT19" EXACT [UniProtKB:P78552] synonym: "IL-13R-alpha-1" EXACT [UniProtKB:P78552] synonym: "IL-13RA-1" EXACT [UniProtKB:P78552] xref: EMBL:AAB37127.1 xref: EMBL:AAD00510.3 xref: EMBL:AAH09960.1 xref: EMBL:CAA70508.1 xref: EMBL:CAA71669.1 xref: UniProtKB:O95646 xref: UniProtKB:P78552 xref: UniProtKB:Q99656 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018197 ! IL13RA1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000455 ! interleukin-13 receptor complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0055653 name: CCL20_HUMAN def: "C-C motif chemokine 20 precursor" [UniProtKB:P78556] synonym: "Beta chemokine exodus-1" EXACT [UniProtKB:P78556] synonym: "CC chemokine LARC" EXACT [UniProtKB:P78556] synonym: "Liver and activation-regulated chemokine" EXACT [UniProtKB:P78556] synonym: "Macrophage inflammatory protein 3 alpha" EXACT [UniProtKB:P78556] synonym: "MIP-3-alpha" EXACT [UniProtKB:P78556] synonym: "Small-inducible cytokine A20" EXACT [UniProtKB:P78556] xref: EMBL:AAB61534.1 xref: EMBL:AAC50943.1 xref: EMBL:AAH20698.1 xref: EMBL:AAX93214.1 xref: EMBL:BAA13191.1 xref: UniProtKB:P78556 xref: UniProtKB:Q53S51 xref: UniProtKB:Q99664 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017265 ! CCL20_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055654 name: SIM1_HUMAN def: "Single-minded homolog 1" [UniProtKB:P81133] xref: EMBL:AAB62395.1 xref: EMBL:CAI19455.1 xref: EMBL:CAI20423.1 xref: UniProtKB:P81133 xref: UniProtKB:Q5TDP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019908 ! SIM1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055655 name: D103A_HUMAN def: "Beta-defensin 103 precursor" [UniProtKB:P81534] synonym: "BD-3" EXACT [UniProtKB:P81534] synonym: "Beta-defensin 3" EXACT [UniProtKB:P81534] synonym: "DEFB-3" EXACT [UniProtKB:P81534] synonym: "Defensin, beta 103" EXACT [UniProtKB:P81534] synonym: "Defensin-like protein" EXACT [UniProtKB:P81534] synonym: "hBD-3" EXACT [UniProtKB:P81534] synonym: "HBD3" EXACT [UniProtKB:P81534] xref: EMBL:AAF73853.1 xref: EMBL:AAG02237.1 xref: EMBL:AAG22030.1 xref: EMBL:AAM62424.1 xref: EMBL:BAB40572.1 xref: EMBL:CAC03097.1 xref: UniProtKB:P81534 xref: UniProtKB:Q8NFG6 xref: UniProtKB:Q9NPF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017515 ! DEFB103A_human relationship: encoded_by CCO:G0017516 ! DEFB103B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000681 ! positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [Term] id: CCO:B0055656 name: SSBP2_HUMAN def: "Single-stranded DNA-binding protein 2" [UniProtKB:P81877] synonym: "Sequence-specific single-stranded-DNA-binding protein 2" EXACT [UniProtKB:P81877] xref: EMBL:AAD27781.1 xref: EMBL:AAH17020.1 xref: EMBL:AAK15803.1 xref: EMBL:BAC11046.1 xref: EMBL:CAB45699.1 xref: UniProtKB:P81877 xref: UniProtKB:Q8N2Q2 xref: UniProtKB:Q9BWW6 xref: UniProtKB:Q9Y4T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020042 ! SSBP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015384 ! ewsr1-ssbp2 physical interaction relationship: participates_in CCO:I0015533 ! ldb1-ssbp2 physical interaction relationship: participates_in CCO:I0015564 ! il1f5-ssbp2 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055657 name: NSBP1_HUMAN def: "Nucleosome-binding protein 1" [UniProtKB:P82970] xref: EMBL:AAH05342.1 xref: EMBL:AAK14062.1 xref: EMBL:AAK14063.1 xref: EMBL:BAC04274.1 xref: UniProtKB:P82970 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018872 ! NSBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068857 ! NSBP1_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0068858 ! NSBP1_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0068859 ! NSBP1_HUMAN-Phosphothreonine31 relationship: transforms_into CCO:B0068860 ! NSBP1_HUMAN-Phosphotyrosine76 [Term] id: CCO:B0055658 name: HCC1_HUMAN def: "Nuclear protein Hcc-1" [UniProtKB:P82979] synonym: "Cytokine-induced protein of 29 kDa" EXACT [UniProtKB:P82979] synonym: "Proliferation-associated cytokine-inducible protein CIP29" EXACT [UniProtKB:P82979] xref: EMBL:AAF28994.1 xref: EMBL:AAH07099.1 xref: EMBL:AAM09686.1 xref: EMBL:CAC37950.1 xref: UniProtKB:P82979 xref: UniProtKB:Q9P066 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018107 ! HCC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015446 ! ddx39-hcc1 physical interaction relationship: participates_in CCO:I0018470 ! bat1-hcc1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0066764 ! HCC1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0066765 ! HCC1_HUMAN-Phosphoserine163 [Term] id: CCO:B0055659 name: HTRA3_HUMAN def: "Probable serine protease HTRA3 precursor" [UniProtKB:P83110] synonym: "EC 3.4.21.-" EXACT [UniProtKB:P83110] synonym: "High-temperature requirement factor A3" EXACT [UniProtKB:P83110] synonym: "Pregnancy-related serine protease" EXACT [UniProtKB:P83110] xref: EMBL:AAH34390.1 xref: EMBL:AAH35717.1 xref: EMBL:AAK71475.2 xref: EMBL:AAP42282.1 xref: EMBL:AAP42283.1 xref: UniProtKB:P83110 xref: UniProtKB:Q7Z7A2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018171 ! HTRA3_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0055660 name: COG7_HUMAN def: "Conserved oligomeric Golgi complex subunit 7" [UniProtKB:P83436] synonym: "COG complex subunit 7" EXACT [UniProtKB:P83436] synonym: "Component of oligomeric Golgi complex 7" EXACT [UniProtKB:P83436] xref: EMBL:AAH00549.1 xref: EMBL:AAH37563.1 xref: EMBL:AAQ88995.1 xref: UniProtKB:P83436 xref: UniProtKB:Q6UWU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017431 ! COG7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000842 ! Golgi transport complex relationship: participates_in CCO:I0016222 ! cog4-cog7-1 physical interaction relationship: participates_in CCO:I0016223 ! cog7-cog4-1 physical interaction relationship: participates_in CCO:I0016224 ! cog5-cog7-1 physical interaction relationship: participates_in CCO:I0016225 ! cog7-cog5-1 physical interaction relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0055661 name: OX26_HUMAN def: "Orexigenic neuropeptide QRFP precursor" [UniProtKB:P83859] synonym: "P518" EXACT [UniProtKB:P83859] xref: EMBL:AAI01128.1 xref: EMBL:AAR24354.1 xref: EMBL:BAC98934.1 xref: EMBL:CAM45757.1 xref: UniProtKB:A3KFJ6 xref: UniProtKB:P83859 xref: UniProtKB:Q495K6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019251 ! QRFP_human relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0069008 ! OX26_HUMAN-Pyrrolidone carboxylic acid91 relationship: transforms_into CCO:B0069009 ! OX26_HUMAN-Phenylalanine amide133 [Term] id: CCO:B0055662 name: ARF5_HUMAN def: "ADP-ribosylation factor 5" [UniProtKB:P84085] xref: EMBL:AAA90927.1 xref: EMBL:AAC51299.1 xref: EMBL:AAH03043.1 xref: EMBL:AAH33104.1 xref: EMBL:AAM12598.1 xref: EMBL:AAP35750.1 xref: UniProtKB:P26437 xref: UniProtKB:P84085 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017006 ! ARF5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055663 name: LBXCO_HUMAN def: "Ladybird homeobox corepressor 1" [UniProtKB:P84550] synonym: "Functional Smad-suppressing element on chromosome 15" EXACT [UniProtKB:P84550] synonym: "Fussel-15" EXACT [UniProtKB:P84550] synonym: "LBX1 corepressor 1" EXACT [UniProtKB:P84550] xref: EMBL:AAV74188.1 xref: UniProtKB:A6NIP4 xref: UniProtKB:P84550 xref: UniProtKB:Q2VWA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018462 ! LBXCOR1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055664 name: RHG08_HUMAN def: "Rho GTPase-activating protein 8" [UniProtKB:P85298] synonym: "Rho-type GTPase-activating protein 8" EXACT [UniProtKB:P85298] xref: EMBL:BAA91614.1 xref: EMBL:BAB14008.1 xref: EMBL:CAI17883.2 xref: EMBL:CAI19475.2 xref: UniProtKB:O75983 xref: UniProtKB:O95695 xref: UniProtKB:P85298 xref: UniProtKB:Q96RW1 xref: UniProtKB:Q96RW2 xref: UniProtKB:Q9HA49 xref: UniProtKB:Q9HC46 xref: UniProtKB:Q9NSG0 xref: UniProtKB:Q9NVX8 xref: UniProtKB:Q9NXL1 xref: UniProtKB:Q9UH20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005481 ! ARHGAP8_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055665 name: POK11_HUMAN def: "HERV-K_22q11.21 provirus ancestral Pol protein" [UniProtKB:P87893] synonym: "HERV-K101 Pol protein" EXACT [UniProtKB:P87893] xref: EMBL:CAA71420.1 xref: UniProtKB:P87893 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055666 name: TSG6_HUMAN def: "Tumor necrosis factor-inducible gene 6 protein precursor" [UniProtKB:P98066] synonym: "Hyaluronate-binding protein" EXACT [UniProtKB:P98066] synonym: "TNF-stimulated gene 6 protein" EXACT [UniProtKB:P98066] synonym: "TSG-6" EXACT [UniProtKB:P98066] synonym: "Tumor necrosis factor, alpha-induced protein 6" EXACT [UniProtKB:P98066] xref: EMBL:AAB00792.1 xref: EMBL:AAH30205.1 xref: EMBL:CAD12353.1 xref: EMBL:CAD13434.1 xref: UniProtKB:P98066 xref: UniProtKB:Q8WWI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020369 ! TNFAIP6_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001664 ! hyaluronic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071605 ! TSG6_HUMAN-Phosphothreonine259 relationship: transforms_into CCO:B0071606 ! TSG6_HUMAN-Phosphothreonine262 [Term] id: CCO:B0055667 name: SHC2_HUMAN def: "SHC-transforming protein 2" [UniProtKB:P98077] synonym: "Protein Sck" EXACT [UniProtKB:P98077] synonym: "SH2 domain protein C2" EXACT [UniProtKB:P98077] synonym: "Src homology 2 domain-containing-transforming protein C2" EXACT [UniProtKB:P98077] xref: EMBL:BAA25798.1 xref: EMBL:CAB96175.1 xref: UniProtKB:O60230 xref: UniProtKB:P98077 xref: UniProtKB:Q9NPL5 xref: UniProtKB:Q9UCX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019893 ! SHC2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0070498 ! SHC2_HUMAN-Phosphotyrosine338 relationship: transforms_into CCO:B0070499 ! SHC2_HUMAN-Phosphotyrosine339 relationship: transforms_into CCO:B0070500 ! SHC2_HUMAN-Phosphotyrosine414 [Term] id: CCO:B0055668 name: DAB2_HUMAN def: "Disabled homolog 2" [UniProtKB:P98082] synonym: "Differentially-expressed protein 2" EXACT [UniProtKB:P98082] synonym: "DOC-2" EXACT [UniProtKB:P98082] xref: EMBL:AAA93195.1 xref: EMBL:AAA98975.1 xref: EMBL:AAB19032.1 xref: EMBL:AAC50824.1 xref: EMBL:AAF05540.1 xref: EMBL:AAF23161.1 xref: EMBL:AAH03064.1 xref: EMBL:EAW55989.1 xref: UniProtKB:A6NES5 xref: UniProtKB:P98082 xref: UniProtKB:Q13598 xref: UniProtKB:Q9BTY0 xref: UniProtKB:Q9UK04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017517 ! DAB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0064616 ! DAB2_HUMAN-Phosphothreonine151 relationship: transforms_into CCO:B0064617 ! DAB2_HUMAN-Phosphotyrosine170 relationship: transforms_into CCO:B0064618 ! DAB2_HUMAN-Phosphothreonine221 relationship: transforms_into CCO:B0064619 ! DAB2_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0064620 ! DAB2_HUMAN-Phosphotyrosine342 relationship: transforms_into CCO:B0064621 ! DAB2_HUMAN-Phosphoserine393 relationship: transforms_into CCO:B0064622 ! DAB2_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0064623 ! DAB2_HUMAN-Phosphoserine401 [Term] id: CCO:B0055669 name: VLDLR_HUMAN def: "Very low-density lipoprotein receptor precursor" [UniProtKB:P98155] synonym: "VLDL receptor" EXACT [UniProtKB:P98155] synonym: "VLDL-R" EXACT [UniProtKB:P98155] xref: EMBL:AAA53684.1 xref: EMBL:AAA61344.1 xref: EMBL:AAB31735.1 xref: EMBL:AAY46157.1 xref: EMBL:BAA03945.1 xref: EMBL:BAA03946.1 xref: EMBL:BAA03969.1 xref: EMBL:CAH72454.1 xref: UniProtKB:P98155 xref: UniProtKB:Q5VVF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011807 ! VLDLR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001362 ! low-density lipoprotein receptor activity relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055670 name: PKD1_HUMAN def: "Polycystin-1 precursor" [UniProtKB:P98161] synonym: "Autosomal dominant polycystic kidney disease 1 protein" EXACT [UniProtKB:P98161] xref: EMBL:AAC37576.1 xref: EMBL:AAC41765.1 xref: EMBL:AAC50128.1 xref: UniProtKB:P98161 xref: UniProtKB:Q15140 xref: UniProtKB:Q15141 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019409 ! PKD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0069329 ! PKD1_HUMAN-Phosphoserine4288 [Term] id: CCO:B0055671 name: LRP2_HUMAN def: "Low-density lipoprotein receptor-related protein 2 precursor" [UniProtKB:P98164] synonym: "Glycoprotein 330" EXACT [UniProtKB:P98164] synonym: "gp330" EXACT [UniProtKB:P98164] synonym: "Megalin" EXACT [UniProtKB:P98164] xref: EMBL:AAB02882.1 xref: EMBL:AAB30825.1 xref: EMBL:AAB41649.1 xref: UniProtKB:O00711 xref: UniProtKB:P98164 xref: UniProtKB:Q16215 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011888 ! LRP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018931 ! atn1-lrp2 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: transforms_into CCO:B0067778 ! LRP2_HUMAN-Phosphoserine4471 [Term] id: CCO:B0055672 name: ZXDA_HUMAN def: "Zinc finger X-linked protein ZXDA" [UniProtKB:P98168] xref: EMBL:AAC37521.1 xref: EMBL:AAH59356.1 xref: EMBL:CAB46717.1 xref: UniProtKB:P98168 xref: UniProtKB:Q9UJP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021010 ! ZXDA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072280 ! ZXDA_HUMAN-Phosphoserine34 [Term] id: CCO:B0055673 name: ZXDB_HUMAN def: "Zinc finger X-linked protein ZXDB" [UniProtKB:P98169] xref: EMBL:AAC37522.1 xref: EMBL:CAB16205.1 xref: EMBL:CAD92603.2 xref: UniProtKB:P98169 xref: UniProtKB:Q9UBB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021011 ! ZXDB_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072281 ! ZXDB_HUMAN-Phosphoserine34 [Term] id: CCO:B0055674 name: BIRC4_HUMAN def: "Baculoviral IAP repeat-containing protein 4" [UniProtKB:P98170] synonym: "E3 ubiquitin-protein ligase XIAP" EXACT [UniProtKB:P98170] synonym: "EC 6.3.2.-" EXACT [UniProtKB:P98170] synonym: "HILP" EXACT [UniProtKB:P98170] synonym: "IAP-like protein" EXACT [UniProtKB:P98170] synonym: "Inhibitor of apoptosis protein 3" EXACT [UniProtKB:P98170] synonym: "X-linked IAP" EXACT [UniProtKB:P98170] synonym: "X-linked inhibitor of apoptosis protein" EXACT [UniProtKB:P98170] xref: EMBL:AAC50373.1 xref: EMBL:AAC50518.1 xref: EMBL:AAH32729.1 xref: EMBL:AAW62257.1 xref: EMBL:CAB95312.1 xref: UniProtKB:P98170 xref: UniProtKB:Q9NQ14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017160 ! BIRC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015064 ! birc4-c8orf32 physical interaction relationship: participates_in CCO:I0015110 ! birc4-dlc2 physical interaction relationship: participates_in CCO:I0015740 ! birc4-birc4 physical interaction relationship: participates_in CCO:I0015839 ! birc4-casp9 physical interaction relationship: participates_in CCO:I0015989 ! tbk1-birc4 phosphorylation relationship: participates_in CCO:I0017875 ! birc4-prss25-3 physical interaction relationship: participates_in CCO:I0017876 ! birc4-diablo-5 physical interaction relationship: participates_in CCO:I0017877 ! birc4-casp9-4 physical interaction relationship: participates_in CCO:I0017953 ! birc4-casp7-1 physical interaction relationship: participates_in CCO:I0017955 ! birc4-casp9-5 direct interaction relationship: participates_in CCO:I0018030 ! birc4-prss25-2 physical interaction relationship: participates_in CCO:I0018031 ! birc4-diablo-4 physical interaction relationship: participates_in CCO:I0018032 ! birc4-casp9-3 physical interaction relationship: participates_in CCO:I0018115 ! birc4-casp3-1 physical interaction relationship: participates_in CCO:I0018179 ! birc4-diablo-1 physical interaction relationship: participates_in CCO:I0018378 ! birc4-diablo-6 physical interaction relationship: participates_in CCO:I0019247 ! birc4-diablo-2 physical interaction relationship: participates_in CCO:I0019323 ! birc4-casp7-2 direct interaction relationship: participates_in CCO:I0019357 ! omi-xiap physical interaction relationship: participates_in CCO:I0019358 ! omi-xiap-1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002168 ! negative regulation of caspase activity relationship: transforms_into CCO:B0063925 ! BIRC4_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0063926 ! BIRC4_HUMAN-Phosphotyrosine139 [Term] id: CCO:B0055675 name: RHG04_HUMAN def: "Rho GTPase-activating protein 4" [UniProtKB:P98171] synonym: "p115" EXACT [UniProtKB:P98171] synonym: "Rho-GAP hematopoietic protein C1" EXACT [UniProtKB:P98171] synonym: "Rho-type GTPase-activating protein 4" EXACT [UniProtKB:P98171] xref: EMBL:BAA09480.1 xref: EMBL:CAA55394.1 xref: UniProtKB:P98171 xref: UniProtKB:Q14144 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019715 ! ARHGAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0069930 ! RHG04_HUMAN-Phosphotyrosine171 [Term] id: CCO:B0055676 name: FGD1_HUMAN def: "FYVE, RhoGEF and PH domain-containing protein 1" [UniProtKB:P98174] synonym: "Faciogenital dysplasia 1 protein" EXACT [UniProtKB:P98174] synonym: "Rho/Rac GEF" EXACT [UniProtKB:P98174] synonym: "Rho/Rac guanine nucleotide exchange factor FGD1" EXACT [UniProtKB:P98174] synonym: "Zinc finger FYVE domain-containing protein 3" EXACT [UniProtKB:P98174] xref: EMBL:AAA57004.1 xref: EMBL:AAH34530.1 xref: EMBL:CAI42222.1 xref: EMBL:EAW93179.1 xref: UniProtKB:P98174 xref: UniProtKB:Q5H999 xref: UniProtKB:Q8N4D9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017784 ! FGD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002156 ! regulation of Cdc42 GTPase activity relationship: transforms_into CCO:B0066174 ! FGD1_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0066175 ! FGD1_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0066176 ! FGD1_HUMAN-Phosphothreonine704 relationship: transforms_into CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: transforms_into CCO:B0066178 ! FGD1_HUMAN-Phosphoserine715 [Term] id: CCO:B0055677 name: CYC_HUMAN def: "Cytochrome c" [UniProtKB:P99999] xref: EMBL:AAA35732.1 xref: EMBL:AAH05299.1 xref: EMBL:AAH08475.1 xref: EMBL:AAH08477.1 xref: EMBL:AAH09578.1 xref: EMBL:AAH09579.1 xref: EMBL:AAH09582.1 xref: EMBL:AAH09587.1 xref: EMBL:AAH09602.1 xref: EMBL:AAH09607.1 xref: EMBL:AAH14359.1 xref: EMBL:AAH14361.1 xref: EMBL:AAH15130.1 xref: EMBL:AAH16006.1 xref: EMBL:AAH21994.1 xref: EMBL:AAH22330.1 xref: EMBL:AAH67222.1 xref: EMBL:AAH68464.1 xref: EMBL:AAH70156.1 xref: EMBL:AAH70346.1 xref: EMBL:AAH71761.1 xref: EMBL:AAP35592.1 xref: EMBL:AAQ96844.1 xref: EMBL:CAD28485.1 xref: EMBL:EAL24239.1 xref: UniProtKB:A4D166 xref: UniProtKB:P00001 xref: UniProtKB:P99999 xref: UniProtKB:Q6NUR2 xref: UniProtKB:Q6NX69 xref: UniProtKB:Q96BV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017508 ! CYCS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017696 ! apaf1-casp9-1 physical interaction relationship: participates_in CCO:I0017697 ! apaf1-casp9-2 physical interaction relationship: participates_in CCO:I0017987 ! cycs-apaf1-1 physical interaction relationship: participates_in CCO:I0017988 ! cycs-apaf1-2 physical interaction relationship: participates_in CCO:I0018488 ! apaf1-casp9-4 physical interaction relationship: participates_in CCO:I0018616 ! apaf1-casp9-3 physical interaction relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000842 ! caspase activation via cytochrome c relationship: transforms_into CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 [Term] id: CCO:B0055678 name: TFAM_HUMAN def: "Transcription factor A, mitochondrial precursor" [UniProtKB:Q00059] synonym: "Mitochondrial transcription factor 1" EXACT [UniProtKB:Q00059] synonym: "MtTF1" EXACT [UniProtKB:Q00059] synonym: "mtTFA" EXACT [UniProtKB:Q00059] synonym: "Transcription factor 6-like 2" EXACT [UniProtKB:Q00059] xref: EMBL:AAA59849.1 xref: EMBL:AAI26367.1 xref: EMBL:AAV38464.1 xref: EMBL:AAV38465.1 xref: EMBL:CAA45562.1 xref: UniProtKB:Q00059 xref: UniProtKB:Q5U0C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020244 ! TFAM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000656 ! regulation of transcription from RNA polymerase I promoter relationship: transforms_into CCO:B0071369 ! TFAM_HUMAN-Phosphoserine193 [Term] id: CCO:B0055679 name: PURA_HUMAN def: "Transcriptional activator protein Pur-alpha" [UniProtKB:Q00577] synonym: "Purine-rich single-stranded DNA-binding protein alpha" EXACT [UniProtKB:Q00577] xref: EMBL:AAA60229.1 xref: UniProtKB:Q00577 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019560 ! PURA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000632 ! DNA unwinding during replication relationship: participates_in CCO:P0000634 ! DNA replication initiation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069636 ! PURA_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0069637 ! PURA_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0069638 ! PURA_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0069639 ! PURA_HUMAN-Phosphotyrosine253 [Term] id: CCO:B0055680 name: BORG5_HUMAN def: "Cdc42 effector protein 1" [UniProtKB:Q00587] synonym: "Binder of Rho GTPases 5" EXACT [UniProtKB:Q00587] synonym: "Serum protein MSE55" EXACT [UniProtKB:Q00587] xref: EMBL:AAA36606.1 xref: EMBL:AAH09356.1 xref: EMBL:CAB42833.1 xref: EMBL:CAG30410.1 xref: UniProtKB:Q00587 xref: UniProtKB:Q96GN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017175 ! CDC42EP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015101 ! cdc42ep1-rbpms physical interaction relationship: participates_in CCO:I0015213 ! cdc42-cdc42ep1 physical interaction relationship: participates_in CCO:I0015500 ! cdc42ep1-krtap4_12 physical interaction relationship: participates_in CCO:I0015540 ! cdc42ep1-mapkap1 physical interaction relationship: participates_in CCO:I0015566 ! cdc42ep1-plscr1 physical interaction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001391 ! positive regulation of pseudopodium formation relationship: transforms_into CCO:B0063961 ! BORG5_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0063962 ! BORG5_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0063963 ! BORG5_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0063964 ! BORG5_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0063965 ! BORG5_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0063966 ! BORG5_HUMAN-Phosphoserine192 relationship: transforms_into CCO:B0063967 ! BORG5_HUMAN-Phosphoserine195 relationship: transforms_into CCO:B0063968 ! BORG5_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0063969 ! BORG5_HUMAN-Phosphoserine353 [Term] id: CCO:B0055681 name: NDP_HUMAN def: "Norrin precursor" [UniProtKB:Q00604] synonym: "Norrie disease protein" EXACT [UniProtKB:Q00604] synonym: "X-linked exudative vitreoretinopathy 2 protein" EXACT [UniProtKB:Q00604] xref: EMBL:AAH29901.1 xref: EMBL:CAA22268.1 xref: EMBL:CAA46639.1 xref: EMBL:CAA46713.1 xref: UniProtKB:Q00604 xref: UniProtKB:Q5JYH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018740 ! NDP_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0055682 name: LFDH_HUMAN def: "Putative guanine nucleotide exchange factor LFDH" [UniProtKB:Q008S8] synonym: "Lung-specific F-box and DH domain-containing protein" EXACT [UniProtKB:Q008S8] xref: EMBL:ABI98401.1 xref: EMBL:CAI42868.2 xref: EMBL:CAI42870.1 xref: EMBL:CAI42871.1 xref: UniProtKB:Q008S8 xref: UniProtKB:Q5JWK2 xref: UniProtKB:Q5JWK3 xref: UniProtKB:Q5JWK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018476 ! LFDH_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0055683 name: PDE1B_HUMAN def: "Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B" [UniProtKB:Q01064] synonym: "63 kDa Cam-PDE" EXACT [UniProtKB:Q01064] synonym: "Cam-PDE 1B" EXACT [UniProtKB:Q01064] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q01064] xref: EMBL:AAA58405.1 xref: EMBL:AAC50769.1 xref: EMBL:AAC51872.1 xref: EMBL:AAH32226.1 xref: UniProtKB:Q01064 xref: UniProtKB:Q92825 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019333 ! PDE1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069163 ! PDE1B_HUMAN-Phosphoserine466 [Term] id: CCO:B0055684 name: TIAR_HUMAN def: "Nucleolysin TIAR" [UniProtKB:Q01085] synonym: "TIA-1-related protein" EXACT [UniProtKB:Q01085] xref: EMBL:AAA36384.1 xref: UniProtKB:Q01085 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020262 ! TIAL1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0071399 ! TIAR_HUMAN-Phosphotyrosine50 [Term] id: CCO:B0055685 name: INSM1_HUMAN def: "Insulinoma-associated protein 1" [UniProtKB:Q01101] synonym: "Zinc finger protein IA-1" EXACT [UniProtKB:Q01101] xref: EMBL:AAA20938.1 xref: EMBL:AAA58680.1 xref: EMBL:CAC36065.1 xref: UniProtKB:Q01101 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018292 ! INSM1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020489 ! tubb4-insm1 physical interaction relationship: participates_in CCO:I0020597 ! mpp3-insm1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055686 name: IL9R_HUMAN def: "Interleukin-9 receptor precursor" [UniProtKB:Q01113] synonym: "CD129 antigen" EXACT [UniProtKB:Q01113] synonym: "IL-9R" EXACT [UniProtKB:Q01113] xref: EMBL:AAA58679.1 xref: EMBL:AAB30844.2 xref: EMBL:AAC29513.1 xref: EMBL:AAD14081.1 xref: EMBL:AAL55435.1 xref: EMBL:CAB96817.1 xref: UniProtKB:Q01113 xref: UniProtKB:Q14634 xref: UniProtKB:Q8WWU1 xref: UniProtKB:Q96TF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018271 ! IL9R_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001265 ! interleukin-9 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055687 name: CD83_HUMAN def: "CD83 antigen precursor" [UniProtKB:Q01151] synonym: "B-cell activation protein" EXACT [UniProtKB:Q01151] synonym: "CD83 antigen" EXACT [UniProtKB:Q01151] synonym: "Cell surface protein HB15" EXACT [UniProtKB:Q01151] xref: EMBL:AAB25085.1 xref: EMBL:AAH30830.1 xref: EMBL:CAA77755.1 xref: UniProtKB:Q01151 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017312 ! CD83_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055688 name: IL5RA_HUMAN def: "Interleukin-5 receptor subunit alpha precursor" [UniProtKB:Q01344] synonym: "CD125 antigen" EXACT [UniProtKB:Q01344] synonym: "CDw125" EXACT [UniProtKB:Q01344] synonym: "IL-5R-alpha" EXACT [UniProtKB:Q01344] xref: EMBL:AAA36110.1 xref: EMBL:AAA59151.1 xref: EMBL:AAA59152.1 xref: EMBL:AAT45457.1 xref: UniProtKB:Q01344 xref: UniProtKB:Q6ISX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018266 ! IL5RA_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001261 ! interleukin-5 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055689 name: TSPY1_HUMAN def: "Testis-specific Y-encoded protein 1" [UniProtKB:Q01534] synonym: "Cancer/testis antigen 78" EXACT [UniProtKB:Q01534] synonym: "CT78" EXACT [UniProtKB:Q01534] xref: EMBL:AAA36570.1 xref: EMBL:AAA61238.1 xref: EMBL:AAB51693.1 xref: EMBL:AAD47421.1 xref: EMBL:AAI21115.1 xref: EMBL:CAA29640.1 xref: UniProtKB:O00216 xref: UniProtKB:P09002 xref: UniProtKB:Q01534 xref: UniProtKB:Q0VAD3 xref: UniProtKB:Q9UNN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020377 ! TSPY1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055690 name: FLI1_HUMAN def: "Friend leukemia integration 1 transcription factor" [UniProtKB:Q01543] synonym: "ERGB transcription factor" EXACT [UniProtKB:Q01543] synonym: "Fli-1 proto-oncogene" EXACT [UniProtKB:Q01543] xref: EMBL:AAA35812.2 xref: EMBL:AAA58479.1 xref: EMBL:AAA58480.1 xref: EMBL:AAB23637.1 xref: EMBL:AAH01670.1 xref: EMBL:AAH10115.1 xref: EMBL:AAK50443.1 xref: EMBL:BAA07463.1 xref: EMBL:CAA47399.1 xref: EMBL:CAA76731.1 xref: UniProtKB:Q01543 xref: UniProtKB:Q14319 xref: UniProtKB:Q92480 xref: UniProtKB:Q9UE07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017811 ! FLI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066203 ! FLI1_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0066204 ! FLI1_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0066205 ! FLI1_HUMAN-Phosphoserine89 [Term] id: CCO:B0055691 name: ILRL1_HUMAN def: "Interleukin-1 receptor-like 1 precursor" [UniProtKB:Q01638] synonym: "Protein ST2" EXACT [UniProtKB:Q01638] xref: EMBL:AAH30975.1 xref: EMBL:AAY15047.1 xref: EMBL:BAA02233.1 xref: EMBL:BAA20539.1 xref: EMBL:BAA82405.2 xref: EMBL:BAA85894.1 xref: UniProtKB:Q01638 xref: UniProtKB:Q53TU7 xref: UniProtKB:Q8NEJ3 xref: UniProtKB:Q9ULV7 xref: UniProtKB:Q9UQ44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018275 ! IL1RL1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001254 ! interleukin receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0015992 ! st2-myd88-1 physical interaction relationship: participates_in CCO:I0015993 ! st2-traf6-1 physical interaction relationship: participates_in CCO:I0015994 ! st2-irak4-1 physical interaction relationship: participates_in CCO:I0018100 ! c9orf26-il1rl1-1 direct interaction relationship: participates_in CCO:I0019313 ! il1rl1-c9orf26-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055692 name: NC2B_HUMAN def: "Protein Dr1" [UniProtKB:Q01658] synonym: "Down-regulator of transcription 1" EXACT [UniProtKB:Q01658] synonym: "NC2-beta" EXACT [UniProtKB:Q01658] synonym: "Negative cofactor 2-beta" EXACT [UniProtKB:Q01658] synonym: "TATA-binding protein-associated phosphoprotein" EXACT [UniProtKB:Q01658] xref: EMBL:AAA58442.1 xref: EMBL:AAH02809.1 xref: EMBL:AAH35507.1 xref: EMBL:AAH68553.1 xref: EMBL:AAP35618.1 xref: EMBL:CAC17578.1 xref: UniProtKB:Q01658 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018723 ! DR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015581 ! dr1-pole3 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068448 ! NC2B_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0068449 ! NC2B_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0068450 ! NC2B_HUMAN-Phosphoserine167 [Term] id: CCO:B0055693 name: TFAP4_HUMAN def: "Transcription factor AP-4" [UniProtKB:Q01664] synonym: "Activating enhancer-binding protein 4" EXACT [UniProtKB:Q01664] xref: EMBL:AAB32235.1 xref: EMBL:AAC17116.1 xref: EMBL:AAH10576.1 xref: EMBL:CAA40683.1 xref: UniProtKB:O60409 xref: UniProtKB:Q01664 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020245 ! TFAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071370 ! TFAP4_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0071371 ! TFAP4_HUMAN-Phosphoserine139 [Term] id: CCO:B0055694 name: CAC1D_HUMAN def: "Voltage-dependent L-type calcium channel subunit alpha-1D" [UniProtKB:Q01668] synonym: "Calcium channel, L type, alpha-1 polypeptide, isoform 2" EXACT [UniProtKB:Q01668] synonym: "Voltage-gated calcium channel subunit alpha Cav1.3" EXACT [UniProtKB:Q01668] xref: EMBL:AAA35629.1 xref: EMBL:AAA58402.1 xref: EMBL:BAA07804.1 xref: UniProtKB:Q01668 xref: UniProtKB:Q13916 xref: UniProtKB:Q13931 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017208 ! CACNA1D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: transforms_into CCO:B0064043 ! CAC1D_HUMAN-Phosphoserine1475 relationship: transforms_into CCO:B0064044 ! CAC1D_HUMAN-Phosphoserine1905 [Term] id: CCO:B0055695 name: SPIB_HUMAN def: "Transcription factor Spi-B" [UniProtKB:Q01892] xref: EMBL:AAH07921.1 xref: EMBL:CAA46878.1 xref: EMBL:CAA65726.1 xref: UniProtKB:Q01892 xref: UniProtKB:Q15359 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020015 ! SPIB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055696 name: CO4A3_HUMAN def: "Collagen alpha-3(IV) chain precursor" [UniProtKB:Q01955] synonym: "Goodpasture antigen" EXACT [UniProtKB:Q01955] xref: EMBL:AAA18942.1 xref: EMBL:AAA18943.1 xref: EMBL:AAA21610.1 xref: EMBL:AAA51556.1 xref: EMBL:AAA52044.1 xref: EMBL:AAB19637.1 xref: EMBL:AAF72632.1 xref: EMBL:AAX93111.1 xref: EMBL:AAY14671.1 xref: EMBL:AAY24251.1 xref: EMBL:BAA25064.1 xref: EMBL:CAA56335.1 xref: EMBL:CAC36101.1 xref: UniProtKB:Q01955 xref: UniProtKB:Q53QQ1 xref: UniProtKB:Q53R14 xref: UniProtKB:Q53RW8 xref: UniProtKB:Q9BQT2 xref: UniProtKB:Q9NYC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017423 ! COL4A3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0064444 ! CO4A3_HUMAN-Phosphoserine1435 relationship: transforms_into CCO:B0064445 ! CO4A3_HUMAN-Phosphoserine1437 [Term] id: CCO:B0055697 name: SC6A3_HUMAN def: "Sodium-dependent dopamine transporter" [UniProtKB:Q01959] synonym: "DA transporter" EXACT [UniProtKB:Q01959] synonym: "DAT" EXACT [UniProtKB:Q01959] synonym: "Solute carrier family 6 member 3" EXACT [UniProtKB:Q01959] xref: EMBL:AAA11754.1 xref: EMBL:AAA19560.1 xref: EMBL:AAA35770.1 xref: EMBL:AAB23443.1 xref: EMBL:AAC41720.1 xref: EMBL:AAC50179.2 xref: EMBL:AAG33844.1 xref: EMBL:AAT38106.1 xref: EMBL:BAA22511.1 xref: UniProtKB:Q01959 xref: UniProtKB:Q14996 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019843 ! SLC6A3_human relationship: has_function CCO:F0001560 ! neurotransmitter:sodium symporter activity relationship: has_function CCO:F0001561 ! dopamine transmembrane transporter activity relationship: has_function CCO:F0001562 ! dopamine:sodium symporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001958 ! monoamine transmembrane transporter activity relationship: has_function CCO:F0002742 ! symporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002032 ! regulation of dopamine metabolic process [Term] id: CCO:B0055698 name: OCRL_HUMAN def: "Inositol polyphosphate 5-phosphatase OCRL-1" [UniProtKB:Q01968] synonym: "EC 3.1.3.36" EXACT [UniProtKB:Q01968] synonym: "Lowe oculocerebrorenal syndrome protein" EXACT [UniProtKB:Q01968] xref: EMBL:AAA59964.2 xref: EMBL:AAB03839.2 xref: EMBL:AAB26926.1 xref: EMBL:AAI30613.1 xref: EMBL:CAI41087.1 xref: EMBL:CAI41088.1 xref: EMBL:CAI42615.1 xref: EMBL:CAI42616.1 xref: EMBL:CAI95696.1 xref: EMBL:EAX11831.1 xref: UniProtKB:A6NKI1 xref: UniProtKB:O60800 xref: UniProtKB:Q01968 xref: UniProtKB:Q15684 xref: UniProtKB:Q15774 xref: UniProtKB:Q4VY09 xref: UniProtKB:Q5JQF1 xref: UniProtKB:Q5JQF2 xref: UniProtKB:Q9UJG5 xref: UniProtKB:Q9UMA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019038 ! OCRL_human relationship: has_function CCO:F0000198 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000376 ! Golgi stack relationship: located_in CCO:C0000379 ! Golgi-associated vesicle relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055699 name: ROR1_HUMAN def: "Tyrosine-protein kinase transmembrane receptor ROR1 precursor" [UniProtKB:Q01973] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q01973] synonym: "Neurotrophic tyrosine kinase, receptor-related 1" EXACT [UniProtKB:Q01973] xref: EMBL:AAA60275.1 xref: EMBL:AAC50714.1 xref: EMBL:CAH71706.1 xref: EMBL:CAI21732.1 xref: EMBL:CAI21932.1 xref: UniProtKB:Q01973 xref: UniProtKB:Q5VVX6 xref: UniProtKB:Q92776 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019771 ! ROR1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0070140 ! ROR1_HUMAN-Phosphotyrosine645 [Term] id: CCO:B0055700 name: ROR2_HUMAN def: "Tyrosine-protein kinase transmembrane receptor ROR2 precursor" [UniProtKB:Q01974] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q01974] synonym: "Neurotrophic tyrosine kinase, receptor-related 2" EXACT [UniProtKB:Q01974] xref: EMBL:AAA60276.1 xref: EMBL:AAG01184.2 xref: EMBL:AAG33132.1 xref: EMBL:BAD92391.1 xref: EMBL:CAH70208.1 xref: EMBL:CAI15694.1 xref: EMBL:CAI17303.1 xref: UniProtKB:Q01974 xref: UniProtKB:Q59GF5 xref: UniProtKB:Q5SPI5 xref: UniProtKB:Q9HAY7 xref: UniProtKB:Q9HB61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019772 ! ROR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0070141 ! ROR2_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0070142 ! ROR2_HUMAN-Sulfoserine469 relationship: transforms_into CCO:B0070143 ! ROR2_HUMAN-Sulfoserine471 relationship: transforms_into CCO:B0070144 ! ROR2_HUMAN-Phosphotyrosine646 [Term] id: CCO:B0055701 name: SF17A_HUMAN def: "Splicing factor, arginine/serine-rich 17A" [UniProtKB:Q02040] synonym: "721P" EXACT [UniProtKB:Q02040] synonym: "B-lymphocyte antigen" EXACT [UniProtKB:Q02040] synonym: "Protein XE7" EXACT [UniProtKB:Q02040] xref: EMBL:AAA36187.1 xref: EMBL:AAA61303.1 xref: EMBL:AAA61304.1 xref: EMBL:AAH28151.1 xref: EMBL:AAI10497.1 xref: EMBL:AAI10498.1 xref: EMBL:CAI41499.1 xref: EMBL:CAI41501.1 xref: UniProtKB:Q02040 xref: UniProtKB:Q02832 xref: UniProtKB:Q2TB98 xref: UniProtKB:Q5JQ74 xref: UniProtKB:Q5JQ76 xref: UniProtKB:Q8N6U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019872 ! SFRS17A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070393 ! SF17A_HUMAN-Phosphoserine537 relationship: transforms_into CCO:B0070394 ! SF17A_HUMAN-Phosphoserine633 [Term] id: CCO:B0055702 name: MEF2A_HUMAN def: "Myocyte-specific enhancer factor 2A" [UniProtKB:Q02078] synonym: "Serum response factor-like protein 1" EXACT [UniProtKB:Q02078] xref: EMBL:AAB17195.1 xref: EMBL:AAB17196.1 xref: EMBL:AAH13437.1 xref: EMBL:CAA44979.1 xref: EMBL:CAA48516.1 xref: EMBL:CAA48517.1 xref: EMBL:CAA76175.1 xref: UniProtKB:O43814 xref: UniProtKB:Q02078 xref: UniProtKB:Q14223 xref: UniProtKB:Q14224 xref: UniProtKB:Q96D14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018599 ! MEF2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068130 ! MEF2A_HUMAN-Phosphoserine98 relationship: transforms_into CCO:B0068131 ! MEF2A_HUMAN-Phosphothreonine108 relationship: transforms_into CCO:B0068132 ! MEF2A_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0068133 ! MEF2A_HUMAN-Phosphoserine255 relationship: transforms_into CCO:B0068134 ! MEF2A_HUMAN-N6-acetyllysine403 relationship: transforms_into CCO:B0068135 ! MEF2A_HUMAN-Phosphoserine408 [Term] id: CCO:B0055703 name: MEF2B_HUMAN def: "Myocyte-specific enhancer factor 2B" [UniProtKB:Q02080] synonym: "RSRFR2" EXACT [UniProtKB:Q02080] synonym: "Serum response factor-like protein 2" EXACT [UniProtKB:Q02080] synonym: "XMEF2" EXACT [UniProtKB:Q02080] xref: EMBL:AAB86982.1 xref: EMBL:AAI26246.1 xref: EMBL:CAA44978.1 xref: EMBL:CAA48515.1 xref: UniProtKB:A0AV80 xref: UniProtKB:Q02080 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018600 ! MEF2B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055704 name: SP2_HUMAN def: "Transcription factor Sp2" [UniProtKB:Q02086] xref: EMBL:AAA36629.1 xref: EMBL:AAH16680.1 xref: EMBL:AAH33814.1 xref: EMBL:BAA05923.2 xref: EMBL:EAW94785.1 xref: UniProtKB:A6NK74 xref: UniProtKB:Q02086 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020000 ! SP2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070777 ! SP2_HUMAN-Phosphothreonine550 [Term] id: CCO:B0055705 name: GCYA3_HUMAN def: "Guanylate cyclase soluble subunit alpha-3" [UniProtKB:Q02108] synonym: "EC 4.6.1.2" EXACT [UniProtKB:Q02108] synonym: "GCS-alpha-1" EXACT [UniProtKB:Q02108] synonym: "GCS-alpha-3" EXACT [UniProtKB:Q02108] synonym: "Soluble guanylate cyclase large subunit" EXACT [UniProtKB:Q02108] xref: EMBL:AAB94794.1 xref: EMBL:AAH28384.1 xref: EMBL:CAA47145.1 xref: EMBL:CAA75738.1 xref: UniProtKB:O43843 xref: UniProtKB:Q02108 xref: UniProtKB:Q8TAH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017899 ! GUCY1A3_human relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000526 ! guanylate cyclase complex, soluble relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction [Term] id: CCO:B0055706 name: GCYB1_HUMAN def: "Guanylate cyclase soluble subunit beta-1" [UniProtKB:Q02153] synonym: "EC 4.6.1.2" EXACT [UniProtKB:Q02153] synonym: "GCS-beta-1" EXACT [UniProtKB:Q02153] synonym: "GCS-beta-3" EXACT [UniProtKB:Q02153] synonym: "Soluble guanylate cyclase small subunit" EXACT [UniProtKB:Q02153] xref: EMBL:AAB94877.1 xref: EMBL:AAH47620.2 xref: EMBL:CAA47144.1 xref: UniProtKB:Q02153 xref: UniProtKB:Q86WY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017900 ! GUCY1B3_human relationship: has_function CCO:F0000801 ! guanylate cyclase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000526 ! guanylate cyclase complex, soluble relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction [Term] id: CCO:B0055707 name: TNR17_HUMAN def: "Tumor necrosis factor receptor superfamily member 17" [UniProtKB:Q02223] synonym: "B-cell maturation protein" EXACT [UniProtKB:Q02223] synonym: "CD269 antigen" EXACT [UniProtKB:Q02223] xref: EMBL:AAB67251.1 xref: EMBL:AAR84240.1 xref: EMBL:BAB60895.1 xref: EMBL:CAA78679.1 xref: EMBL:CAA82690.1 xref: EMBL:CAA82691.1 xref: UniProtKB:Q02223 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020313 ! TNFRSF17_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017366 ! bcma-ztnf4-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055708 name: ZNF45_HUMAN def: "Zinc finger protein 45" [UniProtKB:Q02386] synonym: "BRC1744" EXACT [UniProtKB:Q02386] synonym: "Zinc finger protein 13" EXACT [UniProtKB:Q02386] synonym: "Zinc finger protein KOX5" EXACT [UniProtKB:Q02386] xref: EMBL:AAA36133.1 xref: EMBL:AAA36134.1 xref: EMBL:AAB05653.1 xref: EMBL:AAF63030.1 xref: EMBL:AAH37575.1 xref: EMBL:CAA36562.1 xref: UniProtKB:P17016 xref: UniProtKB:P78472 xref: UniProtKB:Q02386 xref: UniProtKB:Q9P1U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020977 ! ZNF45_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055709 name: SP4_HUMAN def: "Transcription factor Sp4" [UniProtKB:Q02446] synonym: "SPR-1" EXACT [UniProtKB:Q02446] xref: EMBL:CAA48563.1 xref: UniProtKB:O60402 xref: UniProtKB:Q02446 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020003 ! SP4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070785 ! SP4_HUMAN-Phosphoserine691 [Term] id: CCO:B0055710 name: SP3_HUMAN def: "Transcription factor Sp3" [UniProtKB:Q02447] synonym: "SPR-2" EXACT [UniProtKB:Q02447] xref: EMBL:AAA36630.2 xref: EMBL:AAI26415.1 xref: EMBL:AAL58086.1 xref: EMBL:AAM12875.1 xref: EMBL:AAR30505.1 xref: EMBL:AAR30506.1 xref: EMBL:CAA48562.1 xref: EMBL:CAC34575.1 xref: UniProtKB:A0AVL9 xref: UniProtKB:Q02447 xref: UniProtKB:Q69B26 xref: UniProtKB:Q69B27 xref: UniProtKB:Q8TD56 xref: UniProtKB:Q8WWU4 xref: UniProtKB:Q9BQR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020002 ! SP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018447 ! stk19-sp3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070781 ! SP3_HUMAN-Phosphoserine73 relationship: transforms_into CCO:B0070782 ! SP3_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0070783 ! SP3_HUMAN-Phosphoserine566 relationship: transforms_into CCO:B0070784 ! SP3_HUMAN-Phosphoserine646 [Term] id: CCO:B0055711 name: HEN1_HUMAN def: "Helix-loop-helix protein 1" [UniProtKB:Q02575] synonym: "HEN1" EXACT [UniProtKB:Q02575] synonym: "Nescient helix loop helix 1" EXACT [UniProtKB:Q02575] synonym: "NSCL-1" EXACT [UniProtKB:Q02575] xref: EMBL:AAA58634.1 xref: EMBL:AAH13789.1 xref: UniProtKB:Q02575 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018115 ! NHLH1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055712 name: HEN2_HUMAN def: "Helix-loop-helix protein 2" [UniProtKB:Q02577] synonym: "HEN2" EXACT [UniProtKB:Q02577] synonym: "Nescient helix loop helix 2" EXACT [UniProtKB:Q02577] synonym: "NSCL-2" EXACT [UniProtKB:Q02577] xref: EMBL:AAA58635.1 xref: EMBL:AAH96359.1 xref: EMBL:AAH96360.1 xref: EMBL:CAI14533.1 xref: UniProtKB:Q02577 xref: UniProtKB:Q5T1P6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018116 ! NHLH2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055713 name: GHRHR_HUMAN def: "Growth hormone-releasing hormone receptor precursor" [UniProtKB:Q02643] synonym: "GHRH receptor" EXACT [UniProtKB:Q02643] synonym: "GRF receptor" EXACT [UniProtKB:Q02643] synonym: "GRFR" EXACT [UniProtKB:Q02643] xref: EMBL:AAA35890.1 xref: EMBL:AAA58619.1 xref: EMBL:AAB37758.1 xref: EMBL:AAC23789.1 xref: EMBL:AAS59864.1 xref: EMBL:BAC05924.1 xref: UniProtKB:Q02643 xref: UniProtKB:Q99863 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017920 ! GHRHR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055714 name: GUC2A_HUMAN def: "Guanylin precursor" [UniProtKB:Q02747] synonym: "Gap-I" EXACT [UniProtKB:Q02747] synonym: "Guanylate cyclase activator 2A" EXACT [UniProtKB:Q02747] synonym: "Guanylate cyclase-activating protein 1" EXACT [UniProtKB:Q02747] xref: EMBL:AAA35915.1 xref: EMBL:AAA58625.1 xref: EMBL:CAC22258.1 xref: UniProtKB:Q02747 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018093 ! GUCA2A_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0004360 ! guanylate cyclase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055715 name: TIE2_HUMAN def: "Angiopoietin-1 receptor precursor" [UniProtKB:Q02763] synonym: "CD202b antigen" EXACT [UniProtKB:Q02763] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q02763] synonym: "hTIE2" EXACT [UniProtKB:Q02763] synonym: "p140 TEK" EXACT [UniProtKB:Q02763] synonym: "Tunica interna endothelial cell kinase" EXACT [UniProtKB:Q02763] synonym: "Tyrosine-protein kinase receptor TEK" EXACT [UniProtKB:Q02763] synonym: "Tyrosine-protein kinase receptor TIE-2" EXACT [UniProtKB:Q02763] xref: EMBL:AAA61139.1 xref: UniProtKB:Q02763 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020264 ! TEK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0071401 ! TIE2_HUMAN-Phosphotyrosine992 [Term] id: CCO:B0055716 name: RASF7_HUMAN def: "Ras association domain-containing protein 7" [UniProtKB:Q02833] synonym: "HRAS1-related cluster protein 1" EXACT [UniProtKB:Q02833] xref: EMBL:AAA58667.1 xref: EMBL:AAI06922.1 xref: UniProtKB:Q02833 xref: UniProtKB:Q3KP42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019627 ! RASSF7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018368 ! disc1-rassf7-1 physical interaction relationship: participates_in CCO:I0018545 ! disc1-rassf7 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055717 name: RL6_HUMAN def: "60S ribosomal protein L6" [UniProtKB:Q02878] synonym: "Neoplasm-related protein C140" EXACT [UniProtKB:Q02878] synonym: "TAX-responsive enhancer element-binding protein 107" EXACT [UniProtKB:Q02878] synonym: "TAXREB107" EXACT [UniProtKB:Q02878] xref: EMBL:AAB30819.1 xref: EMBL:AAH04138.1 xref: EMBL:AAH20679.1 xref: EMBL:AAH32299.1 xref: EMBL:AAH71912.1 xref: EMBL:AAI04825.1 xref: EMBL:AAI04827.1 xref: EMBL:BAA04491.1 xref: EMBL:BAB17292.1 xref: EMBL:CAA49188.1 xref: UniProtKB:Q02878 xref: UniProtKB:Q2M3Q3 xref: UniProtKB:Q8WW97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019751 ! RPL6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007844 ! stau-dhx9-1 physical interaction relationship: participates_in CCO:I0017199 ! nfkb2-rpl6 physical interaction relationship: participates_in CCO:I0017246 ! map3k14-rpl6 physical interaction relationship: participates_in CCO:I0020045 ! itgb3bp-rpl6 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070090 ! RL6_HUMAN-Phosphoserine127 [Term] id: CCO:B0055718 name: AKA12_HUMAN def: "A-kinase anchor protein 12" [UniProtKB:Q02952] synonym: "A-kinase anchor protein 250 kDa" EXACT [UniProtKB:Q02952] synonym: "AKAP 250" EXACT [UniProtKB:Q02952] synonym: "Gravin" EXACT [UniProtKB:Q02952] synonym: "Myasthenia gravis autoantigen" EXACT [UniProtKB:Q02952] xref: EMBL:AAA35931.1 xref: EMBL:AAB58938.1 xref: EMBL:AAC51366.1 xref: EMBL:BAA19927.1 xref: EMBL:BAE06085.1 xref: EMBL:CAH18338.1 xref: EMBL:CAI13590.1 xref: EMBL:CAI13591.1 xref: EMBL:CAI16151.1 xref: EMBL:CAI20467.1 xref: EMBL:CAI20468.1 xref: UniProtKB:O00310 xref: UniProtKB:O00498 xref: UniProtKB:Q02952 xref: UniProtKB:Q4LE68 xref: UniProtKB:Q5SZ80 xref: UniProtKB:Q5TGN1 xref: UniProtKB:Q68D82 xref: UniProtKB:Q99970 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016941 ! AKAP12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0065502 ! AKA12_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0065503 ! AKA12_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0065504 ! AKA12_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0065505 ! AKA12_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0065506 ! AKA12_HUMAN-Phosphoserine286 relationship: transforms_into CCO:B0065507 ! AKA12_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0065508 ! AKA12_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0065509 ! AKA12_HUMAN-Phosphoserine483 relationship: transforms_into CCO:B0065510 ! AKA12_HUMAN-Phosphoserine505 relationship: transforms_into CCO:B0065511 ! AKA12_HUMAN-Phosphoserine565 relationship: transforms_into CCO:B0065512 ! AKA12_HUMAN-Phosphoserine566 relationship: transforms_into CCO:B0065513 ! AKA12_HUMAN-Phosphoserine568 relationship: transforms_into CCO:B0065514 ! AKA12_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0065515 ! AKA12_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0065516 ! AKA12_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0065517 ! AKA12_HUMAN-Phosphoserine627 relationship: transforms_into CCO:B0065518 ! AKA12_HUMAN-Phosphoserine629 relationship: transforms_into CCO:B0065519 ! AKA12_HUMAN-Phosphoserine645 relationship: transforms_into CCO:B0065520 ! AKA12_HUMAN-Phosphothreonine646 relationship: transforms_into CCO:B0065521 ! AKA12_HUMAN-Phosphoserine648 relationship: transforms_into CCO:B0065522 ! AKA12_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0065523 ! AKA12_HUMAN-Phosphoserine697 relationship: transforms_into CCO:B0065524 ! AKA12_HUMAN-Phosphoserine698 relationship: transforms_into CCO:B0065525 ! AKA12_HUMAN-Phosphoserine732 relationship: transforms_into CCO:B0065526 ! AKA12_HUMAN-Phosphoserine887 relationship: transforms_into CCO:B0065527 ! AKA12_HUMAN-Phosphoserine1331 [Term] id: CCO:B0055719 name: CREM_HUMAN def: "cAMP-responsive element modulator" [UniProtKB:Q03060] synonym: "ICER" EXACT [UniProtKB:Q03060] synonym: "Inducible cAMP early repressor" EXACT [UniProtKB:Q03060] xref: EMBL:AAB03751.1 xref: EMBL:AAC19383.1 xref: EMBL:AAC60616.2 xref: EMBL:AAC60617.2 xref: EMBL:AAF66158.2 xref: EMBL:AAF68266.2 xref: EMBL:AAF68682.1 xref: EMBL:AAH90051.1 xref: EMBL:AAP44115.1 xref: EMBL:BAA03564.1 xref: EMBL:BAA03565.1 xref: EMBL:BAA03566.1 xref: EMBL:BAA03567.1 xref: EMBL:CAA78858.1 xref: EMBL:CAH72496.1 xref: EMBL:CAH72497.1 xref: EMBL:CAI12138.1 xref: EMBL:CAI12139.1 xref: EMBL:CAI12143.1 xref: UniProtKB:O75519 xref: UniProtKB:Q03060 xref: UniProtKB:Q14503 xref: UniProtKB:Q14504 xref: UniProtKB:Q14505 xref: UniProtKB:Q14506 xref: UniProtKB:Q15731 xref: UniProtKB:Q16114 xref: UniProtKB:Q16116 xref: UniProtKB:Q5T9H7 xref: UniProtKB:Q5W1A8 xref: UniProtKB:Q5W1A9 xref: UniProtKB:Q7Z2Q6 xref: UniProtKB:Q9NZ98 xref: UniProtKB:Q9NZ99 xref: UniProtKB:Q9NZB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017453 ! CREM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064463 ! CREM_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0064464 ! CREM_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0064465 ! CREM_HUMAN-Phosphoserine277 [Term] id: CCO:B0055720 name: ENL_HUMAN def: "Protein ENL" [UniProtKB:Q03111] synonym: "YEATS domain-containing protein 1" EXACT [UniProtKB:Q03111] xref: EMBL:AAA58457.1 xref: EMBL:BAA03406.1 xref: UniProtKB:Q03111 xref: UniProtKB:Q14768 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017711 ! MLLT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065067 ! ENL_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0065068 ! ENL_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0065069 ! ENL_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0065070 ! ENL_HUMAN-Phosphoserine359 relationship: transforms_into CCO:B0065071 ! ENL_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0065072 ! ENL_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0065073 ! ENL_HUMAN-Phosphoserine475 [Term] id: CCO:B0055721 name: GNA12_HUMAN def: "Guanine nucleotide-binding protein subunit alpha-12" [UniProtKB:Q03113] synonym: "G alpha-12" EXACT [UniProtKB:Q03113] synonym: "G-protein subunit alpha-12" EXACT [UniProtKB:Q03113] xref: EMBL:AAA35867.1 xref: EMBL:AAD05026.1 xref: EMBL:AAI11465.1 xref: EMBL:AAM12615.1 xref: EMBL:AAP21870.1 xref: UniProtKB:Q03113 xref: UniProtKB:Q2T9L1 xref: UniProtKB:Q86UM8 xref: UniProtKB:Q8TD71 xref: UniProtKB:Q9UDU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017941 ! GNA12_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055722 name: PPARD_HUMAN def: "Peroxisome proliferator-activated receptor delta" [UniProtKB:Q03181] synonym: "NUC1" EXACT [UniProtKB:Q03181] synonym: "NUCI" EXACT [UniProtKB:Q03181] synonym: "Nuclear hormone receptor 1" EXACT [UniProtKB:Q03181] synonym: "Nuclear receptor subfamily 1 group C member 2" EXACT [UniProtKB:Q03181] synonym: "PPAR-beta" EXACT [UniProtKB:Q03181] synonym: "PPAR-delta" EXACT [UniProtKB:Q03181] xref: EMBL:AAA36469.1 xref: EMBL:AAF62553.1 xref: EMBL:AAH02715.1 xref: EMBL:AAH07578.1 xref: EMBL:AAR05439.1 xref: EMBL:BAC78903.1 xref: EMBL:CAB38629.1 xref: EMBL:CAD92505.1 xref: UniProtKB:Q03181 xref: UniProtKB:Q7Z5K0 xref: UniProtKB:Q9BUD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019480 ! PPARD_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002414 ! positive regulation of fat cell differentiation [Term] id: CCO:B0055723 name: UPAR_HUMAN def: "Urokinase plasminogen activator surface receptor precursor" [UniProtKB:Q03405] synonym: "CD87 antigen" EXACT [UniProtKB:Q03405] synonym: "Monocyte activation antigen Mo3" EXACT [UniProtKB:Q03405] synonym: "U-PAR" EXACT [UniProtKB:Q03405] synonym: "uPAR" EXACT [UniProtKB:Q03405] xref: EMBL:AAA17978.1 xref: EMBL:AAA17979.1 xref: EMBL:AAA59862.1 xref: EMBL:AAB60333.1 xref: EMBL:AAB60690.1 xref: EMBL:AAC32739.1 xref: EMBL:AAD14289.1 xref: EMBL:AAD17387.1 xref: EMBL:AAD17388.1 xref: EMBL:AAF71751.1 xref: EMBL:AAH02788.1 xref: EMBL:AAK31795.1 xref: EMBL:AAN86351.1 xref: EMBL:CAA35981.1 xref: EMBL:CAA52191.1 xref: EMBL:CAG33233.1 xref: UniProtKB:Q03405 xref: UniProtKB:Q12876 xref: UniProtKB:Q15845 xref: UniProtKB:Q16887 xref: UniProtKB:Q6IB52 xref: UniProtKB:Q9BWT0 xref: UniProtKB:Q9NYC8 xref: UniProtKB:Q9UD69 xref: UniProtKB:Q9UEA6 xref: UniProtKB:Q9UM92 xref: UniProtKB:Q9UMV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020416 ! PLAUR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004421 ! U-plasminogen activator receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0020111 ! plaur-eef1a1 physical interaction relationship: participates_in CCO:I0020112 ! plaur-sumo2 physical interaction relationship: participates_in CCO:I0020113 ! plaur-pfn2 physical interaction relationship: participates_in CCO:I0020628 ! plaur-surf2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001246 ! regulation of proteolysis [Term] id: CCO:B0055724 name: PTHR1_HUMAN def: "Parathyroid hormone/parathyroid hormone-related peptide receptor precursor" [UniProtKB:Q03431] synonym: "PTH/PTHr receptor" EXACT [UniProtKB:Q03431] synonym: "PTH/PTHrP type I receptor" EXACT [UniProtKB:Q03431] xref: EMBL:AAA36525.1 xref: EMBL:AAA56774.1 xref: EMBL:AAB60657.1 xref: EMBL:AAI12222.1 xref: EMBL:AAI12248.1 xref: EMBL:AAR18076.1 xref: EMBL:CAA48589.1 xref: UniProtKB:Q03431 xref: UniProtKB:Q2M1U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019542 ! PTHR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001329 ! parathyroid hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055725 name: ERCC6_HUMAN def: "DNA excision repair protein ERCC-6" [UniProtKB:Q03468] synonym: "ATP-dependent helicase ERCC6" EXACT [UniProtKB:Q03468] synonym: "Cockayne syndrome protein CSB" EXACT [UniProtKB:Q03468] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q03468] xref: EMBL:AAA52397.1 xref: EMBL:AAO13487.1 xref: EMBL:CAH70291.1 xref: UniProtKB:Q03468 xref: UniProtKB:Q5W0L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017724 ! ERCC6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: participates_in CCO:I0018426 ! polr2a-ercc6-1 physical interaction relationship: participates_in CCO:I0018765 ! xab2-ercc6-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001649 ! positive regulation of RNA elongation relationship: transforms_into CCO:B0065113 ! ERCC6_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0065114 ! ERCC6_HUMAN-Phosphoserine429 relationship: transforms_into CCO:B0065115 ! ERCC6_HUMAN-Phosphoserine430 relationship: transforms_into CCO:B0065116 ! ERCC6_HUMAN-Phosphoserine486 relationship: transforms_into CCO:B0065117 ! ERCC6_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0065118 ! ERCC6_HUMAN-Phosphoserine1142 relationship: transforms_into CCO:B0065119 ! ERCC6_HUMAN-Phosphoserine1348 relationship: transforms_into CCO:B0065120 ! ERCC6_HUMAN-Phosphoserine1461 [Term] id: CCO:B0055726 name: EVX2_HUMAN def: "Homeobox even-skipped homolog protein 2" [UniProtKB:Q03828] synonym: "EVX-2" EXACT [UniProtKB:Q03828] xref: EMBL:AAA52414.1 xref: UniProtKB:Q03828 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017745 ! EVX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055727 name: ZNF85_HUMAN def: "Zinc finger protein 85" [UniProtKB:Q03923] synonym: "HTF1" EXACT [UniProtKB:Q03923] synonym: "Zinc finger protein HPF4" EXACT [UniProtKB:Q03923] xref: EMBL:AAA52689.1 xref: EMBL:AAA58671.1 xref: EMBL:AAA79179.1 xref: UniProtKB:Q03923 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020991 ! ZNF85_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055728 name: ZN117_HUMAN def: "Zinc finger protein 117" [UniProtKB:Q03924] synonym: "h-PLK" EXACT [UniProtKB:Q03924] synonym: "Provirus-linked krueppel" EXACT [UniProtKB:Q03924] synonym: "Zinc finger protein HPF9" EXACT [UniProtKB:Q03924] xref: EMBL:AAA36010.1 xref: EMBL:AAA58666.1 xref: EMBL:AAG41761.1 xref: UniProtKB:Q02313 xref: UniProtKB:Q03924 xref: UniProtKB:Q7Z7Q7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020618 ! ZNF117_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055729 name: ZNF90_HUMAN def: "Zinc finger protein 90" [UniProtKB:Q03938] synonym: "Zinc finger protein HTF9" EXACT [UniProtKB:Q03938] xref: EMBL:AAA36028.1 xref: UniProtKB:Q03938 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020993 ! ZNF90_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055730 name: ARI5A_HUMAN def: "AT-rich interactive domain-containing protein 5A" [UniProtKB:Q03989] synonym: "ARID domain-containing protein 5A" EXACT [UniProtKB:Q03989] synonym: "Modulator recognition factor 1" EXACT [UniProtKB:Q03989] synonym: "MRF-1" EXACT [UniProtKB:Q03989] xref: EMBL:AAA36325.1 xref: EMBL:AAH67301.2 xref: UniProtKB:Q03989 xref: UniProtKB:Q6NX37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017031 ! ARID5A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019017 ! atxn1-arid5a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055731 name: IF4G1_HUMAN def: "Eukaryotic translation initiation factor 4 gamma 1" [UniProtKB:Q04637] synonym: "eIF-4-gamma 1" EXACT [UniProtKB:Q04637] synonym: "eIF-4G 1" EXACT [UniProtKB:Q04637] synonym: "eIF-4G1" EXACT [UniProtKB:Q04637] synonym: "p220" EXACT [UniProtKB:Q04637] xref: EMBL:AAC78443.1 xref: EMBL:AAC78444.1 xref: EMBL:AAC82471.1 xref: EMBL:AAL92872.1 xref: EMBL:AAM69365.1 xref: EMBL:BAA02185.1 xref: EMBL:BAD18554.1 xref: EMBL:CAA04500.1 xref: EMBL:CAI46013.1 xref: UniProtKB:O43177 xref: UniProtKB:O95066 xref: UniProtKB:Q04637 xref: UniProtKB:Q5HYG0 xref: UniProtKB:Q6ZN21 xref: UniProtKB:Q8N102 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018229 ! EIF4G1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016133 ! eif4g-mnk1 physical interaction relationship: participates_in CCO:I0016134 ! mnk1-eif4g physical interaction relationship: participates_in CCO:I0016285 ! eif4g1-eif4a1-3 physical interaction relationship: participates_in CCO:I0016286 ! eif4g1-eif4a2-3 physical interaction relationship: participates_in CCO:I0017277 ! eif4g-pabp1 physical interaction relationship: participates_in CCO:I0018150 ! eif4gi-ncbp2 physical interaction relationship: participates_in CCO:I0018151 ! eif4gi-ncbp1 physical interaction relationship: participates_in CCO:I0018482 ! ncbp2-eif4gi physical interaction relationship: participates_in CCO:I0018484 ! ddx48-eif4gi physical interaction relationship: participates_in CCO:I0018485 ! eif4gi-q9h1j2 physical interaction relationship: participates_in CCO:I0018568 ! eif4g1-eif4a1-2 physical interaction relationship: participates_in CCO:I0018570 ! eif4g1-eif4a1-1 physical interaction relationship: participates_in CCO:I0018571 ! eif4g1-eif4a2-1 physical interaction relationship: participates_in CCO:I0018673 ! eif4g1-eif4a2-2 physical interaction relationship: participates_in CCO:I0019448 ! eif4e-eif4g1-1 direct interaction relationship: participates_in CCO:I0020549 ! eif4g1-anxa5 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0067026 ! IF4G1_HUMAN-Phosphothreonine205 relationship: transforms_into CCO:B0067027 ! IF4G1_HUMAN-Phosphothreonine207 relationship: transforms_into CCO:B0067028 ! IF4G1_HUMAN-Phosphothreonine223 relationship: transforms_into CCO:B0067029 ! IF4G1_HUMAN-Phosphotyrosine594 relationship: transforms_into CCO:B0067030 ! IF4G1_HUMAN-Phosphothreonine647 relationship: transforms_into CCO:B0067031 ! IF4G1_HUMAN-Phosphoserine1093 relationship: transforms_into CCO:B0067032 ! IF4G1_HUMAN-Phosphoserine1146 relationship: transforms_into CCO:B0067033 ! IF4G1_HUMAN-Phosphoserine1148 relationship: transforms_into CCO:B0067034 ! IF4G1_HUMAN-Phosphoserine1186 relationship: transforms_into CCO:B0067035 ! IF4G1_HUMAN-Phosphoserine1188 relationship: transforms_into CCO:B0067036 ! IF4G1_HUMAN-Phosphoserine1210 relationship: transforms_into CCO:B0067037 ! IF4G1_HUMAN-Phosphoserine1232 relationship: transforms_into CCO:B0067038 ! IF4G1_HUMAN-Phosphoserine1597 [Term] id: CCO:B0055732 name: ATP7A_HUMAN def: "Copper-transporting ATPase 1" [UniProtKB:Q04656] synonym: "Copper pump 1" EXACT [UniProtKB:Q04656] synonym: "EC 3.6.3.4" EXACT [UniProtKB:Q04656] synonym: "Menkes disease-associated protein" EXACT [UniProtKB:Q04656] xref: EMBL:AAA16974.1 xref: EMBL:AAA35580.1 xref: EMBL:AAA96010.1 xref: EMBL:AAG47452.1 xref: EMBL:CAA49145.1 xref: EMBL:CAB08160.1 xref: EMBL:CAB08162.2 xref: EMBL:CAB94714.1 xref: UniProtKB:O00227 xref: UniProtKB:O00745 xref: UniProtKB:Q04656 xref: UniProtKB:Q9BYY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017102 ! ATP7A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000489 ! copper-exporting ATPase activity relationship: has_function CCO:F0001598 ! copper ion transmembrane transporter activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002576 ! mercury ion transmembrane transporter activity relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003201 ! superoxide dismutase copper chaperone activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0005035 ! copper-dependent protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006258 ! metal ion transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001709 ! cell soma relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000526 ! regulation of oxidative phosphorylation relationship: participates_in CCO:P0002235 ! neuroprotection relationship: transforms_into CCO:B0063657 ! ATP7A_HUMAN-Phosphoserine353 relationship: transforms_into CCO:B0063658 ! ATP7A_HUMAN-Phosphoserine357 [Term] id: CCO:B0055733 name: EMX1_HUMAN def: "Homeobox protein EMX1" [UniProtKB:Q04741] synonym: "Empty spiracles homolog 1" EXACT [UniProtKB:Q04741] synonym: "Empty spiracles-like protein 1" EXACT [UniProtKB:Q04741] xref: EMBL:AAH37242.1 xref: EMBL:AAH45762.2 xref: EMBL:AAY14744.1 xref: EMBL:CAA48750.1 xref: UniProtKB:Q04741 xref: UniProtKB:Q0D2P0 xref: UniProtKB:Q53T30 xref: UniProtKB:Q86XB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017709 ! EMX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055734 name: EMX2_HUMAN def: "Homeobox protein EMX2" [UniProtKB:Q04743] synonym: "Empty spiracles homolog 2" EXACT [UniProtKB:Q04743] synonym: "Empty spiracles-like protein 2" EXACT [UniProtKB:Q04743] xref: EMBL:AAK95496.1 xref: EMBL:BAB70842.1 xref: EMBL:CAA48751.1 xref: EMBL:CAB82104.1 xref: UniProtKB:Q04743 xref: UniProtKB:Q96NN8 xref: UniProtKB:Q9BQF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017710 ! EMX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017347 ! eif4e-emx2-1 physical interaction relationship: participates_in CCO:I0017348 ! emx2-eif4e-1 physical interaction relationship: participates_in CCO:I0017349 ! eif4e-emx2-2 physical interaction relationship: participates_in CCO:I0019344 ! emx2-eif4e-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055735 name: LGUL_HUMAN def: "Lactoylglutathione lyase" [UniProtKB:Q04760] synonym: "Aldoketomutase" EXACT [UniProtKB:Q04760] synonym: "EC 4.4.1.5" EXACT [UniProtKB:Q04760] synonym: "Glx I" EXACT [UniProtKB:Q04760] synonym: "Glyoxalase I" EXACT [UniProtKB:Q04760] synonym: "Ketone-aldehyde mutase" EXACT [UniProtKB:Q04760] synonym: "Methylglyoxalase" EXACT [UniProtKB:Q04760] synonym: "S-D-lactoylglutathione methylglyoxal lyase" EXACT [UniProtKB:Q04760] xref: EMBL:AAA52565.1 xref: EMBL:AAB49495.1 xref: EMBL:AAD38008.1 xref: EMBL:AAH01741.1 xref: EMBL:AAH11365.1 xref: EMBL:AAH15934.1 xref: EMBL:AAV38790.1 xref: EMBL:AAV38791.1 xref: EMBL:BAA02572.1 xref: EMBL:CAI21586.1 xref: UniProtKB:P78375 xref: UniProtKB:Q04760 xref: UniProtKB:Q5TZW3 xref: UniProtKB:Q96FC0 xref: UniProtKB:Q96J41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018484 ! GLO1_human relationship: has_function CCO:F0000862 ! lactoylglutathione lyase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0055736 name: SSB_HUMAN def: "Single-stranded DNA-binding protein, mitochondrial precursor" [UniProtKB:Q04837] synonym: "Mt-SSB" EXACT [UniProtKB:Q04837] synonym: "MtSSB" EXACT [UniProtKB:Q04837] synonym: "PWP1-interacting protein 17" EXACT [UniProtKB:Q04837] xref: EMBL:AAA36332.1 xref: EMBL:AAH00895.1 xref: EMBL:AAK69112.1 xref: UniProtKB:Q04837 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020044 ! SSBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0070938 ! SSB_HUMAN-Phosphoserine79 [Term] id: CCO:B0055737 name: REL_HUMAN def: "C-Rel proto-oncogene protein" [UniProtKB:Q04864] synonym: "C-Rel protein" EXACT [UniProtKB:Q04864] xref: EMBL:AAA52073.1 xref: EMBL:ABC40747.1 xref: EMBL:CAA52954.1 xref: UniProtKB:Q04864 xref: UniProtKB:Q2PNZ7 xref: UniProtKB:Q6LDY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019667 ! REL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016348 ! rel-hspa1l physical interaction relationship: participates_in CCO:I0016349 ! rel-hspa5 physical interaction relationship: participates_in CCO:I0016350 ! rel-hspa8 physical interaction relationship: participates_in CCO:I0016351 ! rel-hspa9b physical interaction relationship: participates_in CCO:I0016352 ! rel-nfkbie physical interaction relationship: participates_in CCO:I0016353 ! rel-hspa6 physical interaction relationship: participates_in CCO:I0016354 ! rel-hnrph1 physical interaction relationship: participates_in CCO:I0016355 ! rel-c1qbp physical interaction relationship: participates_in CCO:I0016356 ! rel-nfkbia physical interaction relationship: participates_in CCO:I0016357 ! rel-nfkbib physical interaction relationship: participates_in CCO:I0016358 ! rel-nfkb1 physical interaction relationship: participates_in CCO:I0016359 ! rel-actg1 physical interaction relationship: participates_in CCO:I0016360 ! rel-cltc physical interaction relationship: participates_in CCO:I0016361 ! rel-rel physical interaction relationship: participates_in CCO:I0016362 ! rel-wdr37 physical interaction relationship: participates_in CCO:I0016363 ! rel-hsp70_1 physical interaction relationship: participates_in CCO:I0016364 ! rel-nfkb2 physical interaction relationship: participates_in CCO:I0016365 ! rel-q9bzf9 physical interaction relationship: participates_in CCO:I0016366 ! rel-fkbp5 physical interaction relationship: participates_in CCO:I0016367 ! rel-gapd physical interaction relationship: participates_in CCO:I0016368 ! rel-tuba2 physical interaction relationship: participates_in CCO:I0017155 ! rel-flip1 physical interaction relationship: participates_in CCO:I0017156 ! rel-map3k8 physical interaction relationship: participates_in CCO:I0017157 ! rel-papola physical interaction relationship: participates_in CCO:I0017159 ! nfkbia-rel physical interaction relationship: participates_in CCO:I0017167 ! nfkbib-rel physical interaction relationship: participates_in CCO:I0017185 ! nfkbie-rel physical interaction relationship: participates_in CCO:I0017189 ! nfkb2-rel-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069857 ! REL_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0069858 ! REL_HUMAN-Phosphoserine503 [Term] id: CCO:B0055738 name: MUC24_HUMAN def: "Putative mucin core protein 24 precursor" [UniProtKB:Q04900] synonym: "CD164 antigen" EXACT [UniProtKB:Q04900] synonym: "MGC-24" EXACT [UniProtKB:Q04900] synonym: "MUC-24" EXACT [UniProtKB:Q04900] synonym: "Multi-glycosylated core protein 24" EXACT [UniProtKB:Q04900] xref: EMBL:BAA03130.1 xref: EMBL:CAI40700.1 xref: UniProtKB:Q04900 xref: UniProtKB:Q5JSU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018683 ! CD164_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055739 name: RON_HUMAN def: "Macrophage-stimulating protein receptor precursor" [UniProtKB:Q04912] synonym: "CD136 antigen" EXACT [UniProtKB:Q04912] synonym: "CDw136" EXACT [UniProtKB:Q04912] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q04912] synonym: "MSP receptor" EXACT [UniProtKB:Q04912] synonym: "p185-Ron" EXACT [UniProtKB:Q04912] xref: EMBL:CAA49634.1 xref: UniProtKB:Q04912 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019767 ! MST1R_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0070138 ! RON_HUMAN-Phosphotyrosine1353 relationship: transforms_into CCO:B0070139 ! RON_HUMAN-Phosphotyrosine1360 [Term] id: CCO:B0055740 name: PLP2_HUMAN def: "Proteolipid protein 2" [UniProtKB:Q04941] synonym: "Differentiation-dependent protein A4" EXACT [UniProtKB:Q04941] synonym: "Intestinal membrane A4 protein" EXACT [UniProtKB:Q04941] xref: EMBL:AAA35499.1 xref: EMBL:AAB92356.1 xref: EMBL:AAI09067.1 xref: UniProtKB:Q04941 xref: UniProtKB:Q32MM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019445 ! PLP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002557 ! ion transmembrane transporter activity relationship: has_function CCO:F0004222 ! chemokine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017879 ! ccr1-plp2-2 physical interaction relationship: participates_in CCO:I0018193 ! ccr1-plp2-3 colocalization relationship: participates_in CCO:I0018648 ! ccr1-plp2-1 physical interaction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0055741 name: EGR4_HUMAN def: "Early growth response protein 4" [UniProtKB:Q05215] synonym: "AT133" EXACT [UniProtKB:Q05215] synonym: "EGR-4" EXACT [UniProtKB:Q05215] xref: EMBL:AAX88903.1 xref: EMBL:CAA42698.1 xref: EMBL:CAA49214.1 xref: UniProtKB:Q05215 xref: UniProtKB:Q2Z1P5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017667 ! EGR4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055742 name: ZNF91_HUMAN def: "Zinc finger protein 91" [UniProtKB:Q05481] synonym: "HPF7" EXACT [UniProtKB:Q05481] synonym: "Zinc finger protein HTF10" EXACT [UniProtKB:Q05481] xref: EMBL:AAA58672.1 xref: EMBL:AAA59469.1 xref: UniProtKB:Q05481 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020994 ! ZNF91_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017485 ! mitap1-znf91 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055743 name: ZBT16_HUMAN def: "Zinc finger and BTB domain-containing protein 16" [UniProtKB:Q05516] synonym: "Promyelocytic leukemia zinc finger protein" EXACT [UniProtKB:Q05516] synonym: "Zinc finger protein 145" EXACT [UniProtKB:Q05516] synonym: "Zinc finger protein PLZF" EXACT [UniProtKB:Q05516] xref: EMBL:AAC60590.2 xref: EMBL:AAD03619.1 xref: EMBL:AAH26902.1 xref: EMBL:AAH29812.1 xref: EMBL:CAA79489.1 xref: UniProtKB:Q05516 xref: UniProtKB:Q8TAL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020546 ! ZBTB16_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000818 ! PML body relationship: located_in CCO:C0000820 ! nuclear speck relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: participates_in CCO:I0016136 ! plzf-pml-3 direct interaction relationship: participates_in CCO:I0016137 ! plzf-pml-4 direct interaction relationship: participates_in CCO:I0016138 ! plzf-plzf-1 direct interaction relationship: participates_in CCO:I0017801 ! zbtb16-q8iub0-2 direct interaction relationship: participates_in CCO:I0017829 ! zbtb16-q8iub0-3 physical interaction relationship: participates_in CCO:I0017892 ! plzf-pml-5 physical interaction relationship: participates_in CCO:I0017893 ! plzf-pml-7 physical interaction relationship: participates_in CCO:I0017894 ! plzf-plzf-2 physical interaction relationship: participates_in CCO:I0018078 ! pml-plzf-1 colocalization relationship: participates_in CCO:I0018341 ! plzf-pml-1 physical interaction relationship: participates_in CCO:I0018346 ! pml-plzf-2 colocalization relationship: participates_in CCO:I0018410 ! zbtb16-q8iub0-1 physical interaction relationship: participates_in CCO:I0018761 ! zbtb16-q8iub0 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002452 ! negative regulation of myeloid cell differentiation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071959 ! ZBT16_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0071960 ! ZBT16_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0071961 ! ZBT16_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0071962 ! ZBT16_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0071963 ! ZBT16_HUMAN-Phosphothreonine282 relationship: transforms_into CCO:B0071964 ! ZBT16_HUMAN-Phosphoserine628 [Term] id: CCO:B0055744 name: NMDZ1_HUMAN def: "Glutamate [NMDA] receptor subunit zeta-1 precursor" [UniProtKB:Q05586] synonym: "N-methyl-D-aspartate receptor subunit NR1" EXACT [UniProtKB:Q05586] xref: EMBL:AAA21180.1 xref: EMBL:AAA36198.1 xref: EMBL:AAA62111.1 xref: EMBL:AAA62112.1 xref: EMBL:AAB25917.1 xref: EMBL:AAB59360.1 xref: EMBL:AAB59361.1 xref: EMBL:BAA02732.1 xref: EMBL:CAH72874.2 xref: EMBL:CAH72875.2 xref: UniProtKB:A6NLK7 xref: UniProtKB:A6NLR1 xref: UniProtKB:P35437 xref: UniProtKB:Q05586 xref: UniProtKB:Q12867 xref: UniProtKB:Q12868 xref: UniProtKB:Q5VSF7 xref: UniProtKB:Q5VSF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018808 ! GRIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018398 ! erbb4-nmdar1 physical interaction relationship: participates_in CCO:I0019315 ! nmdar1-plcb4 physical interaction relationship: participates_in CCO:P0002011 ! ionotropic glutamate receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068750 ! NMDZ1_HUMAN-Phosphoserine889 relationship: transforms_into CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: transforms_into CCO:B0068752 ! NMDZ1_HUMAN-Phosphoserine896 relationship: transforms_into CCO:B0068753 ! NMDZ1_HUMAN-Phosphoserine897 [Term] id: CCO:B0055745 name: KPCD_HUMAN def: "Protein kinase C delta type" [UniProtKB:Q05655] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q05655] synonym: "nPKC-delta" EXACT [UniProtKB:Q05655] xref: EMBL:AAA03175.1 xref: EMBL:AAA03176.1 xref: EMBL:AAH43350.1 xref: EMBL:BAA01381.1 xref: EMBL:BAG36031.1 xref: EMBL:CAA80249.1 xref: EMBL:EAW65279.1 xref: UniProtKB:B2R834 xref: UniProtKB:Q05655 xref: UniProtKB:Q15144 xref: UniProtKB:Q86XJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018435 ! PRKCD_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019268 ! prkd-fyn-1 physical interaction relationship: participates_in CCO:I0019269 ! prkd-fyn-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002964 ! protein stabilization relationship: transforms_into CCO:B0067415 ! KPCD_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0067416 ! KPCD_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0067417 ! KPCD_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0067418 ! KPCD_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0067419 ! KPCD_HUMAN-Phosphotyrosine313 relationship: transforms_into CCO:B0067420 ! KPCD_HUMAN-Phosphotyrosine334 relationship: transforms_into CCO:B0067421 ! KPCD_HUMAN-Phosphotyrosine374 relationship: transforms_into CCO:B0067422 ! KPCD_HUMAN-Phosphothreonine507 relationship: transforms_into CCO:B0067423 ! KPCD_HUMAN-Phosphoserine645 relationship: transforms_into CCO:B0067424 ! KPCD_HUMAN-Phosphoserine664 [Term] id: CCO:B0055746 name: HME1_HUMAN def: "Homeobox protein engrailed-1" [UniProtKB:Q05925] synonym: "Hu-En-1" EXACT [UniProtKB:Q05925] xref: EMBL:AAA53502.2 xref: EMBL:AAX88967.1 xref: EMBL:EAW95206.1 xref: UniProtKB:Q05925 xref: UniProtKB:Q4ZG44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018140 ! EN1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055747 name: Q05AH0_HUMAN def: "FSHR protein" [UniProtKB:Q05AH0] xref: EMBL:AAI25271.1 xref: UniProtKB:Q05AH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004661 ! FSHR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001304 ! follicle-stimulating hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055748 name: Q05B42_HUMAN def: "SARM1 protein" [UniProtKB:Q05B42] xref: EMBL:AAI22861.1 xref: UniProtKB:Q05B42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019839 ! SARM1_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055749 name: Q05BE4_HUMAN def: "PASK protein" [UniProtKB:Q05BE4] xref: EMBL:AAH50565.1 xref: UniProtKB:Q05BE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019302 ! PASK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055750 name: MBTD1_HUMAN def: "MBT domain-containing protein 1" [UniProtKB:Q05BQ5] xref: EMBL:AAH34364.1 xref: EMBL:AAI01737.1 xref: EMBL:BAA90919.1 xref: EMBL:BAC85763.1 xref: EMBL:EAW94562.1 xref: UniProtKB:Q05BQ5 xref: UniProtKB:Q6ZVU7 xref: UniProtKB:Q9NXU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018580 ! MBTD1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055751 name: Q05BS4_HUMAN def: "HOXA11 protein" [UniProtKB:Q05BS4] xref: EMBL:AAH33706.1 xref: UniProtKB:Q05BS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018176 ! HOXA11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055752 name: Q05BT6_HUMAN def: "CIB2 protein" [UniProtKB:Q05BT6] synonym: "Calcium and integrin binding family member 2, isoform CRA_a" EXACT [UniProtKB:Q05BT6] xref: EMBL:AAH33108.1 xref: EMBL:EAW99183.1 xref: UniProtKB:Q05BT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021081 ! CIB2_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0055753 name: Q05BW2_HUMAN def: "MXD3 protein" [UniProtKB:Q05BW2] xref: EMBL:AAH32586.1 xref: UniProtKB:Q05BW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018555 ! MXD3_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055754 name: Q05BY5_HUMAN def: "ZNF282 protein" [UniProtKB:Q05BY5] xref: EMBL:AAH31686.1 xref: UniProtKB:Q05BY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020692 ! ZNF282_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055755 name: Q05C29_HUMAN def: "ZNF677 protein" [UniProtKB:Q05C29] xref: EMBL:AAH29855.1 xref: UniProtKB:Q05C29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020892 ! ZNF677_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055756 name: Q05C50_HUMAN def: "P2RY13 protein" [UniProtKB:Q05C50] xref: EMBL:AAH29363.1 xref: UniProtKB:Q05C50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019273 ! P2RY13_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055757 name: Q05CQ7_HUMAN def: "ZNF780A protein" [UniProtKB:Q05CQ7] xref: EMBL:AAH21982.1 xref: UniProtKB:Q05CQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020538 ! ZNF780A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055758 name: Q05CR2_HUMAN def: "ZNF248 protein" [UniProtKB:Q05CR2] xref: EMBL:AAH21819.1 xref: UniProtKB:Q05CR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020677 ! ZNF248_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055759 name: Q05D03_HUMAN def: "RHOV protein" [UniProtKB:Q05D03] xref: EMBL:AAH19353.1 xref: UniProtKB:Q05D03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019737 ! RHOV_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055760 name: Q05D58_HUMAN def: "ZNF540 protein" [UniProtKB:Q05D58] xref: EMBL:AAH17940.1 xref: UniProtKB:Q05D58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020804 ! ZNF540_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055761 name: Q05D88_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q05D88] xref: EMBL:AAH17768.1 xref: UniProtKB:Q05D88 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055762 name: Q05DA6_HUMAN def: "ZNF394 protein" [UniProtKB:Q05DA6] xref: EMBL:AAH17051.1 xref: UniProtKB:Q05DA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020727 ! ZNF394_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055763 name: Q05DF4_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q05DF4] xref: EMBL:AAH15622.1 xref: UniProtKB:Q05DF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055764 name: Q05DL7_HUMAN def: "ZNF480 protein" [UniProtKB:Q05DL7] xref: EMBL:AAH07056.1 xref: UniProtKB:Q05DL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020768 ! ZNF480_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055765 name: PTN11_HUMAN def: "Tyrosine-protein phosphatase non-receptor type 11" [UniProtKB:Q06124] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q06124] synonym: "Protein-tyrosine phosphatase 2C" EXACT [UniProtKB:Q06124] synonym: "PTP-1D" EXACT [UniProtKB:Q06124] synonym: "PTP-2C" EXACT [UniProtKB:Q06124] synonym: "SH-PTP2" EXACT [UniProtKB:Q06124] synonym: "SH-PTP3" EXACT [UniProtKB:Q06124] synonym: "SHP-2" EXACT [UniProtKB:Q06124] synonym: "Shp2" EXACT [UniProtKB:Q06124] xref: EMBL:AAA17022.1 xref: EMBL:AAA36611.1 xref: EMBL:AAH08692.1 xref: EMBL:AAP35770.1 xref: EMBL:BAA02740.2 xref: EMBL:CAA50045.1 xref: UniProtKB:Q06124 xref: UniProtKB:Q96HD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019546 ! PTPN11_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001091 ! non-membrane spanning protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007453 ! gab2-grb2-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015977 ! mpzl1-ptpn1 physical interaction relationship: participates_in CCO:I0017689 ! gab1-ptpn11-2 physical interaction relationship: participates_in CCO:I0017705 ! gab1-ptpn11-1 physical interaction relationship: participates_in CCO:I0018404 ! il6st-ptpn1 physical interaction relationship: participates_in CCO:I0018611 ! gab1-ptpn11-3 physical interaction relationship: participates_in CCO:I0019458 ! mpzl1-ptpn1-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069589 ! PTN11_HUMAN-Phosphotyrosine62 relationship: transforms_into CCO:B0069590 ! PTN11_HUMAN-Phosphotyrosine63 relationship: transforms_into CCO:B0069591 ! PTN11_HUMAN-Phosphotyrosine66 relationship: transforms_into CCO:B0069592 ! PTN11_HUMAN-Phosphotyrosine546 relationship: transforms_into CCO:B0069593 ! PTN11_HUMAN-Phosphotyrosine584 relationship: transforms_into CCO:B0069594 ! PTN11_HUMAN-Phosphoserine595 [Term] id: CCO:B0055766 name: REG3A_HUMAN def: "Regenerating islet-derived protein 3 alpha precursor" [UniProtKB:Q06141] synonym: "Pancreatitis-associated protein 1" EXACT [UniProtKB:Q06141] synonym: "Reg III-alpha" EXACT [UniProtKB:Q06141] xref: EMBL:AAA36415.1 xref: EMBL:AAA60020.1 xref: EMBL:AAB24642.1 xref: EMBL:AAH36776.1 xref: EMBL:BAA02728.1 xref: EMBL:CAA48605.1 xref: UniProtKB:Q06141 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019665 ! REG3A_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055767 name: SUH_HUMAN def: "Recombining binding protein suppressor of hairless" [UniProtKB:Q06330] synonym: "CBF-1" EXACT [UniProtKB:Q06330] synonym: "J kappa-recombination signal-binding protein" EXACT [UniProtKB:Q06330] synonym: "RBP-J" EXACT [UniProtKB:Q06330] synonym: "RBP-J kappa" EXACT [UniProtKB:Q06330] synonym: "RBP-JK" EXACT [UniProtKB:Q06330] synonym: "Renal carcinoma antigen NY-REN-30" EXACT [UniProtKB:Q06330] xref: EMBL:AAA16253.1 xref: EMBL:AAA16254.1 xref: EMBL:AAA16356.1 xref: EMBL:AAA60258.1 xref: EMBL:AAH20780.1 xref: EMBL:AAH64976.1 xref: UniProtKB:Q06330 xref: UniProtKB:Q5XKH9 xref: UniProtKB:Q6P1N3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020081 ! RBPJ_human relationship: has_function CCO:F0000028 ! recombinase activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0016284 ! cir-rbpsuh-1 physical interaction relationship: participates_in CCO:I0017377 ! rbpsuh-notch1 physical interaction relationship: participates_in CCO:I0017880 ! rbpsuh-skiip-2 physical interaction relationship: participates_in CCO:I0018321 ! cir-rbpsuh-2 colocalization relationship: participates_in CCO:I0018653 ! rbpsuh-ncor2-3 physical interaction relationship: participates_in CCO:I0018834 ! rbpsuh-skiip-1 physical interaction relationship: participates_in CCO:I0019388 ! rbpsuh-notch1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0055768 name: MEF2C_HUMAN def: "Myocyte-specific enhancer factor 2C" [UniProtKB:Q06413] xref: EMBL:AAA59578.1 xref: EMBL:AAB25838.1 xref: UniProtKB:Q06413 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018601 ! MEF2C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068136 ! MEF2C_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0068137 ! MEF2C_HUMAN-Phosphoserine396 [Term] id: CCO:B0055769 name: MTG8_HUMAN def: "Protein CBFA2T1" [UniProtKB:Q06455] synonym: "Cyclin-D-related protein" EXACT [UniProtKB:Q06455] synonym: "Eight twenty one protein" EXACT [UniProtKB:Q06455] synonym: "Protein ETO" EXACT [UniProtKB:Q06455] synonym: "Protein MTG8" EXACT [UniProtKB:Q06455] synonym: "Zinc finger MYND domain-containing protein 2" EXACT [UniProtKB:Q06455] xref: EMBL:AAB32126.1 xref: EMBL:AAB34819.2 xref: EMBL:AAB34820.2 xref: EMBL:AAC26143.1 xref: EMBL:AAC28931.1 xref: EMBL:AAC28932.1 xref: EMBL:AAH05850.1 xref: EMBL:BAA03089.1 xref: EMBL:BAA03247.1 xref: EMBL:BAA03558.1 xref: EMBL:BAA03559.1 xref: EMBL:BAA03560.1 xref: EMBL:BAA07755.1 xref: EMBL:CAA56311.1 xref: EMBL:CAG33073.1 xref: UniProtKB:O14784 xref: UniProtKB:Q06455 xref: UniProtKB:Q06456 xref: UniProtKB:Q14873 xref: UniProtKB:Q16239 xref: UniProtKB:Q16346 xref: UniProtKB:Q16347 xref: UniProtKB:Q6IBL1 xref: UniProtKB:Q92479 xref: UniProtKB:Q9BRZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018679 ! RUNX1T1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015059 ! abi3-runx1t1 physical interaction relationship: participates_in CCO:I0015373 ! kiaa0470l-runx1t1 physical interaction relationship: participates_in CCO:I0015729 ! runx1t1-wbp11 physical interaction relationship: participates_in CCO:I0015813 ! runx1t1-taf9l physical interaction relationship: participates_in CCO:I0017525 ! runx1t1-ubqln4 physical interaction relationship: participates_in CCO:I0017549 ! runx1t1-atn1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055770 name: TNFC_HUMAN def: "Lymphotoxin-beta" [UniProtKB:Q06643] synonym: "LT-beta" EXACT [UniProtKB:Q06643] synonym: "TNF-C" EXACT [UniProtKB:Q06643] synonym: "Tumor necrosis factor C" EXACT [UniProtKB:Q06643] synonym: "Tumor necrosis factor ligand superfamily member 3" EXACT [UniProtKB:Q06643] xref: EMBL:AAA36191.1 xref: EMBL:AAA99888.1 xref: EMBL:AAB37342.1 xref: EMBL:AAC51769.1 xref: EMBL:AAD18089.1 xref: EMBL:AAH69330.1 xref: EMBL:AAL49954.1 xref: EMBL:AAL49955.1 xref: EMBL:AAO21134.1 xref: EMBL:BAB63395.1 xref: EMBL:CAA75069.1 xref: UniProtKB:P78370 xref: UniProtKB:Q06643 xref: UniProtKB:Q99761 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020302 ! LTB_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016262 ! light-lt_beta-r physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002276 ! positive regulation of interleukin-12 biosynthetic process [Term] id: CCO:B0055771 name: PAX8_HUMAN def: "Paired box protein Pax-8" [UniProtKB:Q06710] xref: EMBL:AAA03539.1 xref: EMBL:AAB34216.1 xref: EMBL:AAB34217.2 xref: EMBL:AAB34218.2 xref: EMBL:AAH01060.1 xref: EMBL:AAX88880.1 xref: EMBL:BAF84880.1 xref: EMBL:EAW73629.1 xref: UniProtKB:Q06710 xref: UniProtKB:Q09155 xref: UniProtKB:Q16337 xref: UniProtKB:Q16338 xref: UniProtKB:Q16339 xref: UniProtKB:Q4ZG35 xref: UniProtKB:Q96J49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019311 ! PAX8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001334 ! thyroid-stimulating hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069131 ! PAX8_HUMAN-Phosphothreonine279 relationship: transforms_into CCO:B0069132 ! PAX8_HUMAN-Phosphothreonine283 [Term] id: CCO:B0055772 name: ZN33A_HUMAN def: "Zinc finger protein 33A" [UniProtKB:Q06730] synonym: "Zinc finger and ZAK-associated protein with KRAB domain" EXACT [UniProtKB:Q06730] synonym: "Zinc finger protein 11A" EXACT [UniProtKB:Q06730] synonym: "Zinc finger protein KOX31" EXACT [UniProtKB:Q06730] synonym: "ZZaPK" EXACT [UniProtKB:Q06730] xref: EMBL:AAO24702.1 xref: EMBL:BAA06541.1 xref: EMBL:CAA48645.1 xref: EMBL:CAA48646.1 xref: EMBL:CAA48648.1 xref: EMBL:CAH69953.1 xref: EMBL:CAH73315.1 xref: UniProtKB:P17013 xref: UniProtKB:Q06730 xref: UniProtKB:Q5VZ86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020712 ! ZNF33A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072115 ! ZN33A_HUMAN-Phosphoserine267 [Term] id: CCO:B0055773 name: ZN33B_HUMAN def: "Zinc finger protein 33B" [UniProtKB:Q06732] synonym: "Zinc finger protein 11B" EXACT [UniProtKB:Q06732] synonym: "Zinc finger protein KOX2" EXACT [UniProtKB:Q06732] xref: EMBL:AAH48313.1 xref: EMBL:CAA36559.1 xref: EMBL:CAA48643.1 xref: EMBL:CAA48644.1 xref: EMBL:CAA48647.1 xref: EMBL:CAD36956.1 xref: EMBL:CAI23623.1 xref: UniProtKB:Q06731 xref: UniProtKB:Q06732 xref: UniProtKB:Q32MA2 xref: UniProtKB:Q86XY8 xref: UniProtKB:Q8NDW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020713 ! ZNF33B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020498 ! znf11b-hap1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055774 name: FMOD_HUMAN def: "Fibromodulin precursor" [UniProtKB:Q06828] synonym: "Collagen-binding 59 kDa protein" EXACT [UniProtKB:Q06828] synonym: "FM" EXACT [UniProtKB:Q06828] synonym: "Keratan sulfate proteoglycan fibromodulin" EXACT [UniProtKB:Q06828] synonym: "KSPG fibromodulin" EXACT [UniProtKB:Q06828] xref: EMBL:CAA51418.1 xref: EMBL:CAA53233.1 xref: UniProtKB:Q06828 xref: UniProtKB:Q15331 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017815 ! FMOD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000721 ! transforming growth factor beta receptor complex assembly relationship: transforms_into CCO:B0066220 ! FMOD_HUMAN-Pyrrolidone carboxylic acid19 relationship: transforms_into CCO:B0066221 ! FMOD_HUMAN-Sulfotyrosine20 relationship: transforms_into CCO:B0066222 ! FMOD_HUMAN-Sulfotyrosine38 relationship: transforms_into CCO:B0066223 ! FMOD_HUMAN-Sulfotyrosine39 relationship: transforms_into CCO:B0066224 ! FMOD_HUMAN-Sulfotyrosine45 relationship: transforms_into CCO:B0066225 ! FMOD_HUMAN-Sulfotyrosine47 relationship: transforms_into CCO:B0066226 ! FMOD_HUMAN-Sulfotyrosine53 relationship: transforms_into CCO:B0066227 ! FMOD_HUMAN-Sulfotyrosine55 [Term] id: CCO:B0055775 name: PRDX1_HUMAN def: "Peroxiredoxin-1" [UniProtKB:Q06830] synonym: "EC 1.11.1.15" EXACT [UniProtKB:Q06830] synonym: "Natural killer cell-enhancing factor A" EXACT [UniProtKB:Q06830] synonym: "NKEF-A" EXACT [UniProtKB:Q06830] synonym: "PAG" EXACT [UniProtKB:Q06830] synonym: "Proliferation-associated gene protein" EXACT [UniProtKB:Q06830] synonym: "Thioredoxin peroxidase 2" EXACT [UniProtKB:Q06830] synonym: "Thioredoxin-dependent peroxide reductase 2" EXACT [UniProtKB:Q06830] xref: EMBL:AAA50464.1 xref: EMBL:AAH07063.1 xref: EMBL:AAH21683.1 xref: EMBL:AAV38545.1 xref: EMBL:ABB84465.1 xref: EMBL:CAA48137.1 xref: EMBL:CAG28580.1 xref: EMBL:CAI13095.1 xref: EMBL:CAI13096.1 xref: EMBL:CAI13097.1 xref: UniProtKB:P35703 xref: UniProtKB:Q06830 xref: UniProtKB:Q2V576 xref: UniProtKB:Q5T154 xref: UniProtKB:Q5T155 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019501 ! PRDX1_human relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0008212 ! peroxiredoxin activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015179 ! prdx1-q96gl3 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0069494 ! PRDX1_HUMAN-Phosphothreonine90 relationship: transforms_into CCO:B0069495 ! PRDX1_HUMAN-Phosphothreonine183 relationship: transforms_into CCO:B0069496 ! PRDX1_HUMAN-Phosphotyrosine194 [Term] id: CCO:B0055776 name: EGR3_HUMAN def: "Early growth response protein 3" [UniProtKB:Q06889] synonym: "EGR-3" EXACT [UniProtKB:Q06889] synonym: "Zinc finger protein pilot" EXACT [UniProtKB:Q06889] xref: EMBL:AAB19317.1 xref: EMBL:AAI04766.1 xref: EMBL:AAI12280.1 xref: EMBL:CAA45275.1 xref: UniProtKB:Q06889 xref: UniProtKB:Q2M3W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017666 ! EGR3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055777 name: Q06976_HUMAN def: "GTP binding protein" [UniProtKB:Q06976] xref: EMBL:CAA49561.1 xref: UniProtKB:Q06976 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055778 name: Q06DQ3_HUMAN def: "Zinc finger protein 300-B" [UniProtKB:Q06DQ3] xref: EMBL:ABI81769.1 xref: UniProtKB:Q06DQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055779 name: ACHD_HUMAN def: "Acetylcholine receptor subunit delta precursor" [UniProtKB:Q07001] xref: EMBL:AAH93923.1 xref: EMBL:AAH93925.1 xref: EMBL:AAY24102.1 xref: EMBL:CAA38759.1 xref: UniProtKB:Q07001 xref: UniProtKB:Q52LH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013659 ! CHRND_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 [Term] id: CCO:B0055780 name: TNR9_HUMAN def: "Tumor necrosis factor receptor superfamily member 9 precursor" [UniProtKB:Q07011] synonym: "4-1BB ligand receptor" EXACT [UniProtKB:Q07011] synonym: "CD137 antigen" EXACT [UniProtKB:Q07011] synonym: "CDw137" EXACT [UniProtKB:Q07011] synonym: "T-cell antigen 4-1BB homolog" EXACT [UniProtKB:Q07011] synonym: "T-cell antigen ILA" EXACT [UniProtKB:Q07011] xref: EMBL:AAA53133.1 xref: EMBL:AAA62478.2 xref: EMBL:AAH06196.1 xref: EMBL:AAR05440.1 xref: EMBL:CAB57398.1 xref: UniProtKB:Q07011 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020322 ! TNFRSF9_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0055781 name: AMPE_HUMAN def: "Glutamyl aminopeptidase" [UniProtKB:Q07075] synonym: "Aminopeptidase A" EXACT [UniProtKB:Q07075] synonym: "APA" EXACT [UniProtKB:Q07075] synonym: "CD249 antigen" EXACT [UniProtKB:Q07075] synonym: "Differentiation antigen gp160" EXACT [UniProtKB:Q07075] synonym: "EAP" EXACT [UniProtKB:Q07075] synonym: "EC 3.4.11.7" EXACT [UniProtKB:Q07075] xref: EMBL:AAA16876.1 xref: EMBL:AAA35522.1 xref: EMBL:AAH94770.1 xref: UniProtKB:Q07075 xref: UniProtKB:Q504U2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016963 ! ENPEP_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0000648 ! membrane alanyl aminopeptidase activity relationship: has_function CCO:F0000680 ! glutamyl aminopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000460 ! brush border relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0065621 ! AMPE_HUMAN-Phosphotyrosine12 [Term] id: CCO:B0055782 name: COGA1_HUMAN def: "Collagen alpha-1(XVI) chain precursor" [UniProtKB:Q07092] xref: EMBL:AAA58427.1 xref: EMBL:AAB25797.1 xref: EMBL:AAQ15204.1 xref: EMBL:BAD92808.1 xref: EMBL:CAA33085.1 xref: EMBL:CAA33142.1 xref: UniProtKB:Q07092 xref: UniProtKB:Q16593 xref: UniProtKB:Q59F89 xref: UniProtKB:Q71RG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017432 ! COL16A1_human relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000221 ! collagen type XVI relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0055783 name: CXCL9_HUMAN def: "C-X-C motif chemokine 9 precursor" [UniProtKB:Q07325] synonym: "Gamma-interferon-induced monokine" EXACT [UniProtKB:Q07325] synonym: "MIG" EXACT [UniProtKB:Q07325] synonym: "Small-inducible cytokine B9" EXACT [UniProtKB:Q07325] xref: EMBL:AAH63122.1 xref: EMBL:AAH95396.1 xref: EMBL:CAA51284.1 xref: UniProtKB:Q07325 xref: UniProtKB:Q503B4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017496 ! CXCL9_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055784 name: PDE4B_HUMAN def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4B" [UniProtKB:Q07343] synonym: "DPDE4" EXACT [UniProtKB:Q07343] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q07343] synonym: "PDE32" EXACT [UniProtKB:Q07343] xref: EMBL:AAA03589.1 xref: EMBL:AAA03593.1 xref: EMBL:AAA36426.1 xref: EMBL:AAB96381.1 xref: UniProtKB:O15443 xref: UniProtKB:Q07343 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019339 ! PDE4B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017818 ! disc1-pde4b physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069173 ! PDE4B_HUMAN-Phosphothreonine184 relationship: transforms_into CCO:B0069174 ! PDE4B_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0069175 ! PDE4B_HUMAN-Phosphotyrosine274 [Term] id: CCO:B0055785 name: MCL1_HUMAN def: "Induced myeloid leukemia cell differentiation protein Mcl-1" [UniProtKB:Q07820] synonym: "Bcl-2-related protein EAT/mcl1" EXACT [UniProtKB:Q07820] synonym: "mcl1/EAT" EXACT [UniProtKB:Q07820] xref: EMBL:AAD13299.1 xref: EMBL:AAF15309.1 xref: EMBL:AAF15310.1 xref: EMBL:AAF15311.1 xref: EMBL:AAF64255.1 xref: EMBL:AAF64256.1 xref: EMBL:AAF74821.1 xref: EMBL:AAG00896.1 xref: EMBL:AAG00904.1 xref: EMBL:AAH17197.1 xref: EMBL:AAH71897.1 xref: EMBL:AAI07736.1 xref: EMBL:AAP35286.1 xref: EMBL:AAY68220.1 xref: EMBL:CAI15503.1 xref: EMBL:CAI15504.1 xref: UniProtKB:Q07820 xref: UniProtKB:Q9HD91 xref: UniProtKB:Q9NRQ3 xref: UniProtKB:Q9NRQ4 xref: UniProtKB:Q9UHR7 xref: UniProtKB:Q9UHR8 xref: UniProtKB:Q9UHR9 xref: UniProtKB:Q9UNJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018590 ! MCL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017808 ! bak1-mcl1 physical interaction relationship: participates_in CCO:I0019471 ! mcl1-bid direct interaction relationship: participates_in CCO:I0019472 ! mcl1-bik direct interaction relationship: participates_in CCO:I0019473 ! mcl1-bbc3 direct interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0068057 ! MCL1_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0068058 ! MCL1_HUMAN-Phosphothreonine163 [Term] id: CCO:B0055786 name: PPARA_HUMAN def: "Peroxisome proliferator-activated receptor alpha" [UniProtKB:Q07869] synonym: "Nuclear receptor subfamily 1 group C member 1" EXACT [UniProtKB:Q07869] synonym: "PPAR-alpha" EXACT [UniProtKB:Q07869] xref: EMBL:AAA36468.1 xref: EMBL:AAB32649.1 xref: EMBL:AAO13489.1 xref: EMBL:CAA68898.1 xref: EMBL:CAG30433.1 xref: EMBL:CAI18764.1 xref: EMBL:CAI22450.1 xref: UniProtKB:Q07869 xref: UniProtKB:Q16241 xref: UniProtKB:Q92486 xref: UniProtKB:Q92689 xref: UniProtKB:Q9Y3N1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019479 ! PPARA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017653 ! hrmt1l1-ppara-1 physical interaction relationship: participates_in CCO:I0019614 ! rxrg-ppara physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001140 ! regulation of fatty acid metabolic process relationship: participates_in CCO:P0001520 ! positive regulation of fatty acid beta-oxidation relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055787 name: RHG01_HUMAN def: "Rho GTPase-activating protein 1" [UniProtKB:Q07960] synonym: "CDC42 GTPase-activating protein" EXACT [UniProtKB:Q07960] synonym: "GTPase-activating protein rhoOGAP" EXACT [UniProtKB:Q07960] synonym: "p50-RhoGAP" EXACT [UniProtKB:Q07960] synonym: "Rho-related small GTPase protein activator" EXACT [UniProtKB:Q07960] synonym: "Rho-type GTPase-activating protein 1" EXACT [UniProtKB:Q07960] xref: EMBL:AAA16142.1 xref: EMBL:AAH18118.1 xref: EMBL:CAA80560.1 xref: UniProtKB:Q07960 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019714 ! ARHGAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015353 ! arhgap1-rhoc physical interaction relationship: participates_in CCO:I0015844 ! arhgap1-rhoa physical interaction relationship: participates_in CCO:I0017267 ! arhgap1-rhoa-1 direct interaction relationship: participates_in CCO:I0017744 ! cdc42-arhgap1-1 direct interaction relationship: participates_in CCO:I0019181 ! arhgap1-cdc42-1 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0069928 ! RHG01_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0069929 ! RHG01_HUMAN-Phosphotyrosine65 [Term] id: CCO:B0055788 name: FOXM1_HUMAN def: "Forkhead box protein M1" [UniProtKB:Q08050] synonym: "Forkhead-related protein FKHL16" EXACT [UniProtKB:Q08050] synonym: "Hepatocyte nuclear factor 3 forkhead homolog 11" EXACT [UniProtKB:Q08050] synonym: "HFH-11" EXACT [UniProtKB:Q08050] synonym: "HNF-3/fork-head homolog 11" EXACT [UniProtKB:Q08050] synonym: "M-phase phosphoprotein 2" EXACT [UniProtKB:Q08050] synonym: "MPM-2 reactive phosphoprotein 2" EXACT [UniProtKB:Q08050] synonym: "Transcription factor Trident" EXACT [UniProtKB:Q08050] synonym: "Winged-helix factor from INS-1 cells" EXACT [UniProtKB:Q08050] xref: EMBL:AAC37541.1 xref: EMBL:AAC51128.1 xref: EMBL:AAC51129.1 xref: EMBL:AAC63595.1 xref: EMBL:AAH06192.1 xref: EMBL:AAH06529.1 xref: EMBL:AAH12863.1 xref: EMBL:AAY26401.1 xref: UniProtKB:O43258 xref: UniProtKB:O43259 xref: UniProtKB:O43260 xref: UniProtKB:Q08050 xref: UniProtKB:Q4ZGG7 xref: UniProtKB:Q9BRL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017823 ! FOXM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066266 ! FOXM1_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0066267 ! FOXM1_HUMAN-Phosphothreonine620 relationship: transforms_into CCO:B0066268 ! FOXM1_HUMAN-Phosphothreonine627 relationship: transforms_into CCO:B0066269 ! FOXM1_HUMAN-Phosphothreonine662 relationship: transforms_into CCO:B0066270 ! FOXM1_HUMAN-Phosphoserine704 [Term] id: CCO:B0055789 name: LG3BP_HUMAN def: "Galectin-3-binding protein precursor" [UniProtKB:Q08380] synonym: "Basement membrane autoantigen p105" EXACT [UniProtKB:Q08380] synonym: "Lectin galactoside-binding soluble 3-binding protein" EXACT [UniProtKB:Q08380] synonym: "Mac-2 BP" EXACT [UniProtKB:Q08380] synonym: "Mac-2-binding protein" EXACT [UniProtKB:Q08380] synonym: "MAC2BP" EXACT [UniProtKB:Q08380] synonym: "Tumor-associated antigen 90K" EXACT [UniProtKB:Q08380] xref: EMBL:AAA36193.1 xref: EMBL:AAH02403.1 xref: EMBL:AAH02998.1 xref: EMBL:AAH15761.1 xref: EMBL:CAA55699.1 xref: UniProtKB:Q08380 xref: UniProtKB:Q7M4S0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018479 ! LGALS3BP_human relationship: has_function CCO:F0001365 ! scavenger receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0016344 ! map3k8-lgals3bp physical interaction relationship: participates_in CCO:I0016474 ! ikbke-lgals3bp physical interaction relationship: participates_in CCO:I0016618 ! map3k1-lgals3bp physical interaction relationship: participates_in CCO:I0016949 ! q9nyj8-lgals3bp physical interaction relationship: participates_in CCO:I0016968 ! tbk1-lgals3bp physical interaction relationship: participates_in CCO:I0017072 ! tradd-lgals3bp physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055790 name: PDE4C_HUMAN def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4C" [UniProtKB:Q08493] synonym: "DPDE1" EXACT [UniProtKB:Q08493] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q08493] synonym: "PDE21" EXACT [UniProtKB:Q08493] xref: EMBL:AAA03591.1 xref: EMBL:AAC83047.1 xref: EMBL:AAD47053.1 xref: EMBL:AAD47054.1 xref: EMBL:AAD47055.1 xref: EMBL:CAA86601.1 xref: UniProtKB:Q08493 xref: UniProtKB:Q9UN44 xref: UniProtKB:Q9UN45 xref: UniProtKB:Q9UN46 xref: UniProtKB:Q9UPJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019340 ! PDE4C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069176 ! PDE4C_HUMAN-Phosphothreonine164 relationship: transforms_into CCO:B0069177 ! PDE4C_HUMAN-Phosphothreonine646 [Term] id: CCO:B0055791 name: DEMA_HUMAN def: "Dematin" [UniProtKB:Q08495] synonym: "Erythrocyte membrane protein band 4.9" EXACT [UniProtKB:Q08495] xref: EMBL:AAA58438.1 xref: EMBL:AAC50223.1 xref: EMBL:AAH06318.1 xref: EMBL:AAH17445.1 xref: EMBL:AAH52805.1 xref: EMBL:AAP36060.1 xref: UniProtKB:Q08495 xref: UniProtKB:Q13215 xref: UniProtKB:Q9BRE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017552 ! EPB49_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019990 ! epb49-dncli2 physical interaction relationship: participates_in CCO:I0020304 ! epb49-procr physical interaction relationship: participates_in CCO:I0020414 ! ptov1-epb49 physical interaction relationship: participates_in CCO:I0020550 ! epb49-snrpd2 physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0064722 ! DEMA_HUMAN-Phosphothreonine10 relationship: transforms_into CCO:B0064723 ! DEMA_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0064724 ! DEMA_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0064725 ! DEMA_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0064726 ! DEMA_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0064727 ! DEMA_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0064728 ! DEMA_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0064729 ! DEMA_HUMAN-Phosphothreonine91 relationship: transforms_into CCO:B0064730 ! DEMA_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0064731 ! DEMA_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0064732 ! DEMA_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0064733 ! DEMA_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0064734 ! DEMA_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0064735 ! DEMA_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0064736 ! DEMA_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0064737 ! DEMA_HUMAN-Phosphoserine372 relationship: transforms_into CCO:B0064738 ! DEMA_HUMAN-Phosphoserine403 [Term] id: CCO:B0055792 name: PDE4D_HUMAN def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4D" [UniProtKB:Q08499] synonym: "DPDE3" EXACT [UniProtKB:Q08499] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q08499] synonym: "PDE43" EXACT [UniProtKB:Q08499] xref: EMBL:AAA03592.1 xref: EMBL:AAA97890.1 xref: EMBL:AAA97891.1 xref: EMBL:AAA97892.1 xref: EMBL:AAC00042.1 xref: EMBL:AAC00069.1 xref: EMBL:AAC00070.1 xref: EMBL:AAC13745.1 xref: EMBL:AAH08390.1 xref: EMBL:AAH36319.1 xref: EMBL:AAN10117.1 xref: EMBL:AAN10118.1 xref: EMBL:AAN10119.1 xref: EMBL:AAP36062.1 xref: EMBL:AAP75760.1 xref: EMBL:AAP75761.1 xref: EMBL:AAQ90404.1 xref: EMBL:CAC03757.1 xref: UniProtKB:O43433 xref: UniProtKB:Q08499 xref: UniProtKB:Q13549 xref: UniProtKB:Q13550 xref: UniProtKB:Q13551 xref: UniProtKB:Q7Z2L8 xref: UniProtKB:Q8IV84 xref: UniProtKB:Q8IVA9 xref: UniProtKB:Q8IVD2 xref: UniProtKB:Q8IVD3 xref: UniProtKB:Q96HL4 xref: UniProtKB:Q9HCX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019341 ! PDE4D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069178 ! PDE4D_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0069179 ! PDE4D_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0069180 ! PDE4D_HUMAN-Phosphothreonine25 relationship: transforms_into CCO:B0069181 ! PDE4D_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0069182 ! PDE4D_HUMAN-Phosphoserine202 [Term] id: CCO:B0055793 name: CD47_HUMAN def: "Leukocyte surface antigen CD47 precursor" [UniProtKB:Q08722] synonym: "Antigenic surface determinant protein OA3" EXACT [UniProtKB:Q08722] synonym: "CD47 antigen" EXACT [UniProtKB:Q08722] synonym: "IAP" EXACT [UniProtKB:Q08722] synonym: "Integrin-associated protein" EXACT [UniProtKB:Q08722] synonym: "Protein MER6" EXACT [UniProtKB:Q08722] xref: EMBL:AAH10016.1 xref: EMBL:AAH12884.1 xref: EMBL:AAH37306.1 xref: EMBL:AAP35553.1 xref: EMBL:CAA49196.1 xref: EMBL:CAA80977.1 xref: UniProtKB:Q08722 xref: UniProtKB:Q53Y71 xref: UniProtKB:Q96A60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017303 ! CD47_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001239 ! positive regulation of cell-cell adhesion relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation relationship: transforms_into CCO:B0064169 ! CD47_HUMAN-Pyrrolidone carboxylic acid19 [Term] id: CCO:B0055794 name: ADCY1_HUMAN def: "Adenylate cyclase type 1" [UniProtKB:Q08828] synonym: "Adenylate cyclase type I" EXACT [UniProtKB:Q08828] synonym: "Adenylyl cyclase 1" EXACT [UniProtKB:Q08828] synonym: "ATP pyrophosphate-lyase 1" EXACT [UniProtKB:Q08828] synonym: "Ca(2+)/calmodulin-activated adenylyl cyclase" EXACT [UniProtKB:Q08828] synonym: "EC 4.6.1.1" EXACT [UniProtKB:Q08828] xref: EMBL:AAA02907.1 xref: EMBL:AAS07467.1 xref: UniProtKB:Q08828 xref: UniProtKB:Q75MI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016910 ! ADCY1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001817 ! calcium- and calmodulin-responsive adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0055795 name: FGL1_HUMAN def: "Fibrinogen-like protein 1 precursor" [UniProtKB:Q08830] synonym: "Hepassocin" EXACT [UniProtKB:Q08830] synonym: "Hepatocyte-derived fibrinogen-related protein 1" EXACT [UniProtKB:Q08830] synonym: "HFREP-1" EXACT [UniProtKB:Q08830] synonym: "HP-041" EXACT [UniProtKB:Q08830] synonym: "LFIRE-1" EXACT [UniProtKB:Q08830] synonym: "Liver fibrinogen-related protein 1" EXACT [UniProtKB:Q08830] xref: EMBL:AAH07047.1 xref: EMBL:AAP35281.1 xref: EMBL:AAY68216.1 xref: EMBL:BAA03336.1 xref: EMBL:BAB70690.1 xref: UniProtKB:A6NKU4 xref: UniProtKB:Q08830 xref: UniProtKB:Q4PJH9 xref: UniProtKB:Q53YF1 xref: UniProtKB:Q96KW6 xref: UniProtKB:Q96QM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017802 ! FGL1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055796 name: ITK_HUMAN def: "Tyrosine-protein kinase ITK/TSK" [UniProtKB:Q08881] synonym: "EC 2.7.10.2" EXACT [UniProtKB:Q08881] synonym: "Kinase EMT" EXACT [UniProtKB:Q08881] synonym: "T-cell-specific kinase" EXACT [UniProtKB:Q08881] synonym: "Tyrosine-protein kinase Lyk" EXACT [UniProtKB:Q08881] xref: EMBL:AAA36748.1 xref: EMBL:AAB28072.2 xref: EMBL:AAI09078.1 xref: EMBL:AAI09079.1 xref: EMBL:BAA02873.1 xref: UniProtKB:Q08881 xref: UniProtKB:Q32ML7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018345 ! ITK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0067161 ! ITK_HUMAN-Phosphotyrosine180 relationship: transforms_into CCO:B0067162 ! ITK_HUMAN-Phosphotyrosine512 relationship: transforms_into CCO:B0067163 ! ITK_HUMAN-Phosphoserine565 [Term] id: CCO:B0055797 name: Q08AC8_HUMAN def: "ANK2 protein" [UniProtKB:Q08AC8] xref: EMBL:AAI25236.1 xref: UniProtKB:Q08AC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013480 ! ANK2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055798 name: ZN844_HUMAN def: "Zinc finger protein 844" [UniProtKB:Q08AG5] xref: EMBL:AAI25187.1 xref: EMBL:BAG53579.1 xref: EMBL:CAI46141.1 xref: EMBL:EAW84257.1 xref: UniProtKB:Q08AG5 xref: UniProtKB:Q5JPI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022822 ! ZNF844_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055799 name: VAC14_HUMAN def: "Protein VAC14 homolog" [UniProtKB:Q08AM6] synonym: "Tax1-binding protein 2" EXACT [UniProtKB:Q08AM6] xref: EMBL:AAB03813.1 xref: EMBL:AAH00536.2 xref: EMBL:AAH07214.2 xref: EMBL:AAI25109.1 xref: EMBL:AAI25110.1 xref: EMBL:BAB15145.1 xref: EMBL:CAG33624.1 xref: UniProtKB:Q08AM6 xref: UniProtKB:Q13174 xref: UniProtKB:Q6IA12 xref: UniProtKB:Q7L4Y1 xref: UniProtKB:Q9BW96 xref: UniProtKB:Q9H6V6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020431 ! VAC14_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055800 name: Q08AQ7_HUMAN xref: UniProtKB:Q08AQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055801 name: Q08AR7_HUMAN def: "PIP5K3 protein" [UniProtKB:Q08AR7] xref: EMBL:AAI25054.1 xref: UniProtKB:Q08AR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017851 ! PIP5K3_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055802 name: Q08AR8_HUMAN def: "PIP5K3 protein" [UniProtKB:Q08AR8] xref: EMBL:AAI25053.1 xref: UniProtKB:Q08AR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017851 ! PIP5K3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055803 name: ZN543_HUMAN def: "Zinc finger protein 543" [UniProtKB:Q08ER8] xref: EMBL:AAI01013.1 xref: EMBL:AAI01014.1 xref: EMBL:AAI01015.1 xref: EMBL:AAI01016.1 xref: EMBL:BAD18681.1 xref: EMBL:CAD39190.1 xref: UniProtKB:Q08ER8 xref: UniProtKB:Q495U9 xref: UniProtKB:Q495V0 xref: UniProtKB:Q6ZMP4 xref: UniProtKB:Q8NCX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020806 ! ZNF543_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055804 name: DMPK_HUMAN def: "Myotonin-protein kinase" [UniProtKB:Q09013] synonym: "DM-kinase" EXACT [UniProtKB:Q09013] synonym: "DMK" EXACT [UniProtKB:Q09013] synonym: "DMPK" EXACT [UniProtKB:Q09013] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q09013] synonym: "MDPK" EXACT [UniProtKB:Q09013] synonym: "MT-PK" EXACT [UniProtKB:Q09013] synonym: "Myotonic dystrophy protein kinase" EXACT [UniProtKB:Q09013] xref: EMBL:AAA36205.1 xref: EMBL:AAA36206.1 xref: EMBL:AAA64884.1 xref: EMBL:AAA75235.1 xref: EMBL:AAA75236.1 xref: EMBL:AAA75237.1 xref: EMBL:AAA75238.1 xref: EMBL:AAA75239.1 xref: EMBL:AAA75240.1 xref: EMBL:AAA87583.1 xref: EMBL:AAB31800.1 xref: EMBL:AAC14448.1 xref: EMBL:AAC14449.1 xref: EMBL:AAC14450.1 xref: EMBL:AAC14451.1 xref: UniProtKB:Q09013 xref: UniProtKB:Q16205 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017586 ! DMPK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018835 ! dmpk-pln-3 phosphorylation relationship: participates_in CCO:I0018836 ! dmpk-pln-4 phosphorylation relationship: participates_in CCO:I0018888 ! ubqln4-dmpk physical interaction relationship: participates_in CCO:I0018935 ! atn1-dmpk physical interaction relationship: participates_in CCO:I0018970 ! atxn1-dmpk physical interaction relationship: participates_in CCO:I0019027 ! atxn1-dmpk-1 physical interaction relationship: participates_in CCO:I0019261 ! dmpk-pln-1 phosphorylation relationship: participates_in CCO:I0019262 ! dmpk-pln-2 phosphorylation relationship: participates_in CCO:I0020542 ! dmpk-gabarap physical interaction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0064787 ! DMPK_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0064788 ! DMPK_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0064789 ! DMPK_HUMAN-Phosphothreonine244 [Term] id: CCO:B0055805 name: NCBP1_HUMAN def: "Nuclear cap-binding protein subunit 1" [UniProtKB:Q09161] synonym: "80 kDa nuclear cap-binding protein" EXACT [UniProtKB:Q09161] synonym: "CBP80" EXACT [UniProtKB:Q09161] synonym: "NCBP 80 kDa subunit" EXACT [UniProtKB:Q09161] xref: EMBL:AAH01450.1 xref: EMBL:BAA06769.1 xref: EMBL:BAD92470.1 xref: EMBL:CAA56334.1 xref: EMBL:CAI12861.1 xref: EMBL:CAI15431.1 xref: UniProtKB:Q09161 xref: UniProtKB:Q59G76 xref: UniProtKB:Q5T1V0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018724 ! NCBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016200 ! ncbp1-ncbp2-1 direct interaction relationship: participates_in CCO:I0016201 ! ncbp1-ncbp2-2 direct interaction relationship: participates_in CCO:I0016202 ! ncbp1-ncbp2-3 direct interaction relationship: participates_in CCO:I0018150 ! eif4gi-ncbp2 physical interaction relationship: participates_in CCO:I0018151 ! eif4gi-ncbp1 physical interaction relationship: participates_in CCO:I0018250 ! ncbp1-ncbp2-4 direct interaction relationship: participates_in CCO:I0018251 ! ncbp1-ncbp2-5 direct interaction relationship: participates_in CCO:I0018482 ! ncbp2-eif4gi physical interaction relationship: participates_in CCO:I0018483 ! eif4g3-ncbp1 physical interaction relationship: participates_in CCO:P0001441 ! positive regulation of mRNA 3'-end processing relationship: transforms_into CCO:B0068451 ! NCBP1_HUMAN-Phosphothreonine21 relationship: transforms_into CCO:B0068452 ! NCBP1_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0068453 ! NCBP1_HUMAN-Phosphoserine674 [Term] id: CCO:B0055806 name: ZN415_HUMAN def: "Zinc finger protein 415" [UniProtKB:Q09FC8] xref: EMBL:AAH63880.1 xref: EMBL:AAH69668.1 xref: EMBL:AAP35086.1 xref: EMBL:ABI51309.1 xref: EMBL:ABI51310.1 xref: EMBL:ABI51311.1 xref: EMBL:ABI51312.1 xref: EMBL:BAA92059.1 xref: UniProtKB:Q09FC7 xref: UniProtKB:Q09FC8 xref: UniProtKB:Q09FC9 xref: UniProtKB:Q09FD0 xref: UniProtKB:Q6NSZ2 xref: UniProtKB:Q6P3S0 xref: UniProtKB:Q9NUR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020738 ! ZNF415_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055807 name: Q09LL4_HUMAN def: "CD40" [UniProtKB:Q09LL4] xref: EMBL:ABI49511.1 xref: UniProtKB:Q09LL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055808 name: ZN763_HUMAN def: "Zinc finger protein 763" [UniProtKB:Q0D2J5] xref: EMBL:AAI05712.2 xref: EMBL:AAI05713.2 xref: EMBL:AAI05714.2 xref: UniProtKB:Q0D2J5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020926 ! ZNF763_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055809 name: RIPP1_HUMAN def: "Protein ripply1" [UniProtKB:Q0D2K3] xref: EMBL:AAI05692.1 xref: EMBL:AAI05693.1 xref: EMBL:AAI10437.1 xref: EMBL:AAI27251.1 xref: EMBL:CAI40159.1 xref: EMBL:CAI40160.1 xref: EMBL:EAX02733.1 xref: UniProtKB:A0JP63 xref: UniProtKB:Q0D2K3 xref: UniProtKB:Q0VGB3 xref: UniProtKB:Q5JRB8 xref: UniProtKB:Q5JRB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019745 ! RIPPLY1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0055810 name: Q0EFC9_HUMAN def: "TC4 protein" [UniProtKB:Q0EFC9] xref: EMBL:BAF31259.1 xref: UniProtKB:Q0EFC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021082 ! TC4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055811 name: Q0GM61_HUMAN def: "Visual system homeobox 1 transcript variant 5" [UniProtKB:Q0GM61] xref: EMBL:ABI23977.1 xref: UniProtKB:Q0GM61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020465 ! VSX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055812 name: TBC8B_HUMAN def: "TBC1 domain family member 8B" [UniProtKB:Q0IIM8] xref: EMBL:AAI22565.1 xref: EMBL:BAA91071.1 xref: EMBL:BAC85735.1 xref: EMBL:CAI39548.1 xref: EMBL:CAI40161.1 xref: UniProtKB:Q0IIM8 xref: UniProtKB:Q5JRB7 xref: UniProtKB:Q6ZVX5 xref: UniProtKB:Q9NXE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020178 ! TBC1D8B_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0055813 name: Q0IJ52_HUMAN def: "EMR3 protein" [UniProtKB:Q0IJ52] xref: EMBL:AAI21132.2 xref: UniProtKB:Q0IJ52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017706 ! EMR3_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0055814 name: Q0MT80_HUMAN def: "Epithelial cell transforming sequence 2 oncogene protein splice variant b" [UniProtKB:Q0MT80] xref: EMBL:ABH10140.1 xref: UniProtKB:Q0MT80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021083 ! ECT2_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0055815 name: Q0P5U9_HUMAN def: "CREB/ATF bZIP transcription factor" [UniProtKB:Q0P5U9] xref: EMBL:AAH60807.1 xref: UniProtKB:Q0P5U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005955 ! CREBZF_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055816 name: Q0P6G1_HUMAN def: "ZNF527 protein" [UniProtKB:Q0P6G1] xref: EMBL:AAH14325.1 xref: UniProtKB:Q0P6G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020798 ! ZNF527_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055817 name: Q0PKG6_HUMAN def: "Reverse transcriptase" [UniProtKB:Q0PKG6] xref: EMBL:ABG91576.1 xref: UniProtKB:Q0PKG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021077 ! pol_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055818 name: PLCX2_HUMAN def: "Phosphatidylinositol-specific phospholipase C X domain-containing protein 2" [UniProtKB:Q0VAA5] synonym: "PI-PLC X domain-containing protein 2" EXACT [UniProtKB:Q0VAA5] xref: EMBL:AAI21156.1 xref: EMBL:AAI21157.1 xref: EMBL:BAB71103.1 xref: UniProtKB:Q0VAA5 xref: UniProtKB:Q96N12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019440 ! PLCXD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069404 ! PLCX2_HUMAN-Phosphotyrosine221 [Term] id: CCO:B0055819 name: Q0VAB0_HUMAN def: "TBXA2R protein" [UniProtKB:Q0VAB0] xref: EMBL:AAI21149.1 xref: UniProtKB:Q0VAB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020119 ! TBXA2R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001301 ! thromboxane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055820 name: Q0VAC9_HUMAN def: "Nuclear receptor subfamily 1, group I, member 3" [UniProtKB:Q0VAC9] xref: EMBL:AAI21121.1 xref: UniProtKB:Q0VAC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055821 name: Q0VAJ6_HUMAN def: "ZNF195 protein" [UniProtKB:Q0VAJ6] xref: EMBL:AAI21030.1 xref: UniProtKB:Q0VAJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020649 ! ZNF195_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055822 name: RGF1B_HUMAN def: "Ras-GEF domain-containing family member 1B" [UniProtKB:Q0VAM2] synonym: "GPI gamma-4" EXACT [UniProtKB:Q0VAM2] xref: EMBL:AAI21004.1 xref: EMBL:AAI21005.1 xref: EMBL:AAY40982.1 xref: EMBL:AAY41054.1 xref: EMBL:BAB71130.1 xref: UniProtKB:Q0VAM1 xref: UniProtKB:Q0VAM2 xref: UniProtKB:Q4W5L7 xref: UniProtKB:Q4W5M3 xref: UniProtKB:Q96MY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019692 ! RASGEF1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0069908 ! RGF1B_HUMAN-Phosphotyrosine77 [Term] id: CCO:B0055823 name: DYH14_HUMAN def: "Dynein heavy chain 14, axonemal" [UniProtKB:Q0VDD8] synonym: "Axonemal beta dynein heavy chain 14" EXACT [UniProtKB:Q0VDD8] synonym: "Ciliary dynein heavy chain 14" EXACT [UniProtKB:Q0VDD8] xref: EMBL:AAI19717.1 xref: EMBL:AAI19718.1 xref: EMBL:CAI95150.1 xref: EMBL:CAI95641.1 xref: EMBL:CAI95642.2 xref: EMBL:EAW69735.1 xref: UniProtKB:A6NG62 xref: UniProtKB:A6NNL2 xref: UniProtKB:Q0VDD8 xref: UniProtKB:Q0VDD9 xref: UniProtKB:Q4VXC7 xref: UniProtKB:Q4VXG4 xref: UniProtKB:Q4VXG5 xref: UniProtKB:Q5VU33 xref: UniProtKB:Q5VU34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017648 ! DNAH14_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000995 ! dynein complex relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0055824 name: ADIG_HUMAN def: "Adipogenin" [UniProtKB:Q0VDE8] xref: EMBL:AAI19705.1 xref: EMBL:AAI19706.1 xref: UniProtKB:Q0VDE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016916 ! ADIG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002414 ! positive regulation of fat cell differentiation [Term] id: CCO:B0055825 name: Q0VFW9_HUMAN def: "C3orf41 protein" [UniProtKB:Q0VFW9] synonym: "HCG2039480, isoform CRA_a" EXACT [UniProtKB:Q0VFW9] xref: EMBL:AAI18552.1 xref: EMBL:AAI18663.1 xref: EMBL:EAW64686.1 xref: UniProtKB:Q0VFW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021084 ! C3orf41_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055826 name: Q0VFZ9_HUMAN xref: UniProtKB:Q0VFZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055827 name: MESP2_HUMAN def: "Mesoderm posterior protein 2" [UniProtKB:Q0VG99] xref: EMBL:AAI11414.1 xref: EMBL:DAA00304.1 xref: UniProtKB:Q0VG99 xref: UniProtKB:Q7RTU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018606 ! MESP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055828 name: Q0ZAJ0_HUMAN def: "MSH2+ins9a isoform" [UniProtKB:Q0ZAJ0] xref: EMBL:ABG49491.1 xref: UniProtKB:Q0ZAJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005126 ! MSH2_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0055829 name: Q0ZAJ1_HUMAN def: "MSH2-Ex5 isoform" [UniProtKB:Q0ZAJ1] xref: EMBL:ABG49490.1 xref: UniProtKB:Q0ZAJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005126 ! MSH2_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0055830 name: Q0ZAJ2_HUMAN def: "MSH2-Ex3 isoform" [UniProtKB:Q0ZAJ2] xref: EMBL:ABG49489.1 xref: UniProtKB:Q0ZAJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005126 ! MSH2_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0055831 name: Q0ZAJ4_HUMAN def: "MLH1-Ex(15-18) isoform" [UniProtKB:Q0ZAJ4] xref: EMBL:ABG49487.1 xref: UniProtKB:Q0ZAJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005100 ! MLH1_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0055832 name: Q0ZAJ7_HUMAN def: "MLH1-Ex6 isoform" [UniProtKB:Q0ZAJ7] xref: EMBL:ABG49484.1 xref: UniProtKB:Q0ZAJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005100 ! MLH1_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0055833 name: NEXN_HUMAN def: "Nexilin" [UniProtKB:Q0ZGT2] synonym: "F-actin binding protein" EXACT [UniProtKB:Q0ZGT2] synonym: "Nelin" EXACT [UniProtKB:Q0ZGT2] xref: EMBL:AAB28815.1 xref: EMBL:AAD29607.1 xref: EMBL:AAH17827.1 xref: EMBL:AAH55084.1 xref: EMBL:AAI11396.1 xref: EMBL:AAI14445.1 xref: EMBL:AAI14446.1 xref: EMBL:ABE97925.1 xref: EMBL:BAB71622.1 xref: UniProtKB:A0PJ84 xref: UniProtKB:Q0D2H2 xref: UniProtKB:Q0ZGT2 xref: UniProtKB:Q14CC2 xref: UniProtKB:Q14CC3 xref: UniProtKB:Q16081 xref: UniProtKB:Q7Z2X0 xref: UniProtKB:Q96DL0 xref: UniProtKB:Q9Y2V1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018761 ! NEXN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: participates_in CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis relationship: transforms_into CCO:B0068585 ! NEXN_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0068586 ! NEXN_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0068587 ! NEXN_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0068588 ! NEXN_HUMAN-Phosphothreonine370 relationship: transforms_into CCO:B0068589 ! NEXN_HUMAN-Phosphoserine569 [Term] id: CCO:B0055834 name: DBP_HUMAN def: "D site-binding protein" [UniProtKB:Q10586] synonym: "Albumin D box-binding protein" EXACT [UniProtKB:Q10586] synonym: "Albumin D-element-binding protein" EXACT [UniProtKB:Q10586] synonym: "TAXREB302" EXACT [UniProtKB:Q10586] xref: EMBL:AAA81374.1 xref: EMBL:AAB18668.1 xref: EMBL:AAB50219.1 xref: EMBL:AAH11965.1 xref: EMBL:AAP35482.1 xref: EMBL:BAA05833.1 xref: UniProtKB:Q10586 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017527 ! DBP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0055835 name: TEF_HUMAN def: "Thyrotroph embryonic factor" [UniProtKB:Q10587] xref: EMBL:AAA81373.1 xref: EMBL:AAB06497.1 xref: EMBL:AAH39258.1 xref: EMBL:AAH42476.1 xref: EMBL:CAD97856.1 xref: EMBL:CAG30478.1 xref: EMBL:CAG46626.1 xref: EMBL:CAI23516.1 xref: UniProtKB:Q10587 xref: UniProtKB:Q15729 xref: UniProtKB:Q7Z3J7 xref: UniProtKB:Q8IU94 xref: UniProtKB:Q96TG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020228 ! TEF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055836 name: BST2_HUMAN def: "Bone marrow stromal antigen 2 precursor" [UniProtKB:Q10589] synonym: "BST-2" EXACT [UniProtKB:Q10589] synonym: "CD317 antigen" EXACT [UniProtKB:Q10589] synonym: "HM1.24 antigen" EXACT [UniProtKB:Q10589] xref: EMBL:AAH33873.1 xref: EMBL:BAA05679.1 xref: EMBL:BAD96844.1 xref: UniProtKB:Q10589 xref: UniProtKB:Q53G07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017183 ! BST2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055837 name: SMF_HUMAN def: "Protein SMF" [UniProtKB:Q12766] xref: EMBL:AAB51697.1 xref: EMBL:AAH51025.1 xref: EMBL:BAA12107.1 xref: UniProtKB:Q12766 xref: UniProtKB:Q86UG3 xref: UniProtKB:Q9UMF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019950 ! SMF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055838 name: SCAP_HUMAN def: "Sterol regulatory element-binding protein cleavage-activating protein" [UniProtKB:Q12770] synonym: "SCAP" EXACT [UniProtKB:Q12770] synonym: "SREBP cleavage-activating protein" EXACT [UniProtKB:Q12770] xref: EMBL:AAH20987.1 xref: EMBL:BAA12111.2 xref: EMBL:BAB55088.1 xref: EMBL:BAC11673.1 xref: UniProtKB:Q12770 xref: UniProtKB:Q8N2E0 xref: UniProtKB:Q8WUA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019844 ! SCAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000691 ! positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response relationship: participates_in CCO:P0002386 ! negative regulation of cholesterol biosynthetic process relationship: participates_in CCO:P0002513 ! positive regulation of low-density lipoprotein receptor biosynthetic process relationship: transforms_into CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: transforms_into CCO:B0070342 ! SCAP_HUMAN-Phosphoserine851 relationship: transforms_into CCO:B0070343 ! SCAP_HUMAN-Phosphoserine907 [Term] id: CCO:B0055839 name: ARHG5_HUMAN def: "Rho guanine nucleotide exchange factor 5" [UniProtKB:Q12774] synonym: "Guanine nucleotide regulatory protein TIM" EXACT [UniProtKB:Q12774] synonym: "Oncogene TIM" EXACT [UniProtKB:Q12774] synonym: "p60 TIM" EXACT [UniProtKB:Q12774] synonym: "Transforming immortalized mammary oncogene" EXACT [UniProtKB:Q12774] xref: EMBL:AAA18010.1 xref: EMBL:AAC12958.1 xref: EMBL:AAH10046.1 xref: EMBL:AAH11839.1 xref: EMBL:AAH14555.1 xref: EMBL:BAD18708.1 xref: EMBL:EAW80096.1 xref: UniProtKB:A6NNJ2 xref: UniProtKB:Q12774 xref: UniProtKB:Q6ZML7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017015 ! ARHGEF5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018826 ! rhoa-arhgef5-3 physical interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0065729 ! ARHG5_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0065730 ! ARHG5_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0065731 ! ARHG5_HUMAN-Phosphoserine445 relationship: transforms_into CCO:B0065732 ! ARHG5_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0065733 ! ARHG5_HUMAN-Phosphotyrosine1097 relationship: transforms_into CCO:B0065734 ! ARHG5_HUMAN-Phosphotyrosine1100 relationship: transforms_into CCO:B0065735 ! ARHG5_HUMAN-Phosphoserine1126 relationship: transforms_into CCO:B0065736 ! ARHG5_HUMAN-Phosphotyrosine1370 [Term] id: CCO:B0055840 name: KCMA1_HUMAN def: "Calcium-activated potassium channel subunit alpha-1" [UniProtKB:Q12791] synonym: "BK channel" EXACT [UniProtKB:Q12791] synonym: "BKCA alpha" EXACT [UniProtKB:Q12791] synonym: "Calcium-activated potassium channel, subfamily M subunit alpha-1" EXACT [UniProtKB:Q12791] synonym: "hSlo" EXACT [UniProtKB:Q12791] synonym: "K(VCA)alpha" EXACT [UniProtKB:Q12791] synonym: "KCa1.1" EXACT [UniProtKB:Q12791] synonym: "Maxi K channel" EXACT [UniProtKB:Q12791] synonym: "MaxiK" EXACT [UniProtKB:Q12791] synonym: "Slo homolog" EXACT [UniProtKB:Q12791] synonym: "Slo-alpha" EXACT [UniProtKB:Q12791] synonym: "Slo1" EXACT [UniProtKB:Q12791] synonym: "Slowpoke homolog" EXACT [UniProtKB:Q12791] xref: EMBL:AAA50173.1 xref: EMBL:AAA50216.1 xref: EMBL:AAA85104.1 xref: EMBL:AAA92290.1 xref: EMBL:AAB65837.1 xref: EMBL:AAB88802.1 xref: EMBL:AAC50353.1 xref: EMBL:AAD31173.1 xref: EMBL:AAH62659.1 xref: EMBL:AAK91504.1 xref: EMBL:BAD06365.1 xref: EMBL:BAD06397.1 xref: EMBL:CAI14074.1 xref: EMBL:CAI14082.1 xref: EMBL:CAI16162.1 xref: EMBL:CAI16171.1 xref: EMBL:CAI39730.1 xref: EMBL:CAI40870.1 xref: UniProtKB:Q12791 xref: UniProtKB:Q12886 xref: UniProtKB:Q12917 xref: UniProtKB:Q12921 xref: UniProtKB:Q12960 xref: UniProtKB:Q13150 xref: UniProtKB:Q5SQR9 xref: UniProtKB:Q96LG8 xref: UniProtKB:Q9UBB0 xref: UniProtKB:Q9UQK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018388 ! KCNMA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001602 ! regulation of aldosterone metabolic process relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0067286 ! KCMA1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0067287 ! KCMA1_HUMAN-Phosphothreonine763 relationship: transforms_into CCO:B0067288 ! KCMA1_HUMAN-Phosphoserine765 relationship: transforms_into CCO:B0067289 ! KCMA1_HUMAN-Phosphoserine977 relationship: transforms_into CCO:B0067290 ! KCMA1_HUMAN-Phosphoserine978 relationship: transforms_into CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 relationship: transforms_into CCO:B0067292 ! KCMA1_HUMAN-Phosphothreonine1088 [Term] id: CCO:B0055841 name: PNRC1_HUMAN def: "Proline-rich nuclear receptor coactivator 1" [UniProtKB:Q12796] synonym: "B4-2 protein" EXACT [UniProtKB:Q12796] synonym: "Proline-rich protein 2" EXACT [UniProtKB:Q12796] xref: EMBL:AAA85576.1 xref: EMBL:AAH18112.1 xref: EMBL:CAI16243.1 xref: EMBL:CAI16244.1 xref: UniProtKB:Q12796 xref: UniProtKB:Q5T7J6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019459 ! PNRC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055842 name: TFCP2_HUMAN def: "Alpha-globin transcription factor CP2" [UniProtKB:Q12800] synonym: "SAA3 enhancer factor" EXACT [UniProtKB:Q12800] synonym: "Transcription factor LSF" EXACT [UniProtKB:Q12800] xref: EMBL:AAA21324.1 xref: EMBL:AAA21325.1 xref: EMBL:AAH03634.1 xref: UniProtKB:Q12800 xref: UniProtKB:Q12801 xref: UniProtKB:Q9UD77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020248 ! TFCP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019139 ! coil-tfcp2 physical interaction relationship: participates_in CCO:I0020189 ! tfcp2-casp8 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055843 name: AKP13_HUMAN def: "A-kinase anchor protein 13" [UniProtKB:Q12802] synonym: "AKAP 13" EXACT [UniProtKB:Q12802] synonym: "AKAP-Lbc" EXACT [UniProtKB:Q12802] synonym: "Breast cancer nuclear receptor-binding auxiliary protein" EXACT [UniProtKB:Q12802] synonym: "Guanine nucleotide exchange factor Lbc" EXACT [UniProtKB:Q12802] synonym: "Human thyroid-anchoring protein 31" EXACT [UniProtKB:Q12802] synonym: "LBC oncogene" EXACT [UniProtKB:Q12802] synonym: "Lymphoid blast crisis oncogene" EXACT [UniProtKB:Q12802] synonym: "Non-oncogenic Rho GTPase-specific GTP exchange factor" EXACT [UniProtKB:Q12802] synonym: "P47" EXACT [UniProtKB:Q12802] synonym: "Protein kinase A-anchoring protein 13" EXACT [UniProtKB:Q12802] xref: EMBL:AAA58670.1 xref: EMBL:AAC50065.1 xref: EMBL:AAD21311.1 xref: EMBL:AAD40799.1 xref: EMBL:AAH50312.1 xref: EMBL:AAL11723.1 xref: EMBL:AAL40923.1 xref: EMBL:BAB62913.1 xref: EMBL:BAD92651.1 xref: UniProtKB:Q12802 xref: UniProtKB:Q14572 xref: UniProtKB:Q59FP6 xref: UniProtKB:Q86W90 xref: UniProtKB:Q8WXQ6 xref: UniProtKB:Q96JP6 xref: UniProtKB:Q96P79 xref: UniProtKB:Q9Y5T0 xref: UniProtKB:Q9Y5T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016948 ! AKAP13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0065560 ! AKP13_HUMAN-Phosphoserine983 relationship: transforms_into CCO:B0065561 ! AKP13_HUMAN-Phosphoserine1559 relationship: transforms_into CCO:B0065562 ! AKP13_HUMAN-Phosphoserine1645 relationship: transforms_into CCO:B0065563 ! AKP13_HUMAN-Phosphoserine1647 relationship: transforms_into CCO:B0065564 ! AKP13_HUMAN-Phosphoserine1876 relationship: transforms_into CCO:B0065565 ! AKP13_HUMAN-Phosphoserine1929 relationship: transforms_into CCO:B0065566 ! AKP13_HUMAN-Phosphoserine1932 relationship: transforms_into CCO:B0065567 ! AKP13_HUMAN-Phosphoserine2398 relationship: transforms_into CCO:B0065568 ! AKP13_HUMAN-Phosphoserine2402 relationship: transforms_into CCO:B0065569 ! AKP13_HUMAN-Phosphoserine2703 relationship: transforms_into CCO:B0065570 ! AKP13_HUMAN-Phosphoserine2709 relationship: transforms_into CCO:B0065571 ! AKP13_HUMAN-Phosphoserine2728 [Term] id: CCO:B0055844 name: KCNH2_HUMAN def: "Potassium voltage-gated channel subfamily H member 2" [UniProtKB:Q12809] synonym: "eag homolog" EXACT [UniProtKB:Q12809] synonym: "Eag-related protein 1" EXACT [UniProtKB:Q12809] synonym: "Erg1" EXACT [UniProtKB:Q12809] synonym: "Ether-a-go-go-related gene potassium channel 1" EXACT [UniProtKB:Q12809] synonym: "Ether-a-go-go-related protein 1" EXACT [UniProtKB:Q12809] synonym: "H-ERG" EXACT [UniProtKB:Q12809] synonym: "Voltage-gated potassium channel subunit Kv11.1" EXACT [UniProtKB:Q12809] xref: EMBL:AAA62473.1 xref: EMBL:AAC69709.1 xref: EMBL:AAH01914.2 xref: EMBL:AAH04311.2 xref: EMBL:AAL37559.1 xref: EMBL:BAA37096.1 xref: EMBL:BAB19682.1 xref: EMBL:CAA09232.1 xref: EMBL:CAD54447.1 xref: UniProtKB:O75418 xref: UniProtKB:O75680 xref: UniProtKB:Q12809 xref: UniProtKB:Q9BT72 xref: UniProtKB:Q9BUT7 xref: UniProtKB:Q9H3P0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018391 ! KCNH2_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001519 ! delayed rectifier potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020353 ! kcnh2-ndufs6 physical interaction relationship: participates_in CCO:I0020509 ! arhh-kcnh2 physical interaction relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055845 name: RB40B_HUMAN def: "Ras-related protein Rab-40B" [UniProtKB:Q12829] synonym: "Rar protein" EXACT [UniProtKB:Q12829] synonym: "SOCS box-containing protein RAR" EXACT [UniProtKB:Q12829] xref: EMBL:AAA17031.1 xref: EMBL:AAH18039.1 xref: UniProtKB:Q12829 xref: UniProtKB:Q8WVG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019641 ! RAB40B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055846 name: BPTF_HUMAN def: "Nucleosome-remodeling factor subunit BPTF" [UniProtKB:Q12830] synonym: "Bromodomain and PHD finger-containing transcription factor" EXACT [UniProtKB:Q12830] synonym: "Fetal Alz-50 clone 1 protein" EXACT [UniProtKB:Q12830] synonym: "Fetal Alzheimer antigen" EXACT [UniProtKB:Q12830] xref: EMBL:AAA97522.1 xref: EMBL:AAH67234.1 xref: EMBL:AAP22284.1 xref: EMBL:BAA89208.1 xref: UniProtKB:Q12830 xref: UniProtKB:Q6NX67 xref: UniProtKB:Q7Z7D6 xref: UniProtKB:Q9UIG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017176 ! BPTF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0063970 ! BPTF_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0063971 ! BPTF_HUMAN-Phosphoserine572 relationship: transforms_into CCO:B0063972 ! BPTF_HUMAN-Phosphoserine763 relationship: transforms_into CCO:B0063973 ! BPTF_HUMAN-Phosphoserine817 relationship: transforms_into CCO:B0063974 ! BPTF_HUMAN-Phosphotyrosine839 relationship: transforms_into CCO:B0063975 ! BPTF_HUMAN-Phosphothreonine1064 relationship: transforms_into CCO:B0063976 ! BPTF_HUMAN-Phosphoserine1300 relationship: transforms_into CCO:B0063977 ! BPTF_HUMAN-Phosphoserine1827 relationship: transforms_into CCO:B0063978 ! BPTF_HUMAN-Phosphoserine1833 relationship: transforms_into CCO:B0063979 ! BPTF_HUMAN-Phosphoserine2098 [Term] id: CCO:B0055847 name: PO4F2_HUMAN def: "POU domain, class 4, transcription factor 2" [UniProtKB:Q12837] synonym: "Brain-specific homeobox/POU domain protein 3B" EXACT [UniProtKB:Q12837] synonym: "Brn-3B" EXACT [UniProtKB:Q12837] xref: EMBL:AAA16509.1 xref: EMBL:AAA36393.1 xref: EMBL:CAA50589.1 xref: UniProtKB:Q12837 xref: UniProtKB:Q13883 xref: UniProtKB:Q14987 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019462 ! POU4F2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055848 name: FSTL1_HUMAN def: "Follistatin-related protein 1 precursor" [UniProtKB:Q12841] synonym: "Follistatin-like 1" EXACT [UniProtKB:Q12841] xref: EMBL:AAA66062.1 xref: EMBL:AAH00055.1 xref: EMBL:BAA28707.1 xref: EMBL:BAD12167.1 xref: EMBL:BAF82077.1 xref: EMBL:BAG35192.1 xref: EMBL:EAW79526.1 xref: UniProtKB:Q12841 xref: UniProtKB:Q549Z0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017841 ! FSTL1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:B0055849 name: Q12843_HUMAN def: "Breakpoint cluster region protein" [UniProtKB:Q12843] xref: EMBL:AAB60390.1 xref: UniProtKB:Q12843 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004156 ! BCR_human relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0055850 name: Q12845_HUMAN def: "Putative uncharacterized protein BCR" [UniProtKB:Q12845] xref: EMBL:AAB60391.1 xref: UniProtKB:Q12845 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004156 ! BCR_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055851 name: CNTN1_HUMAN def: "Contactin-1 precursor" [UniProtKB:Q12860] synonym: "Glycoprotein gp135" EXACT [UniProtKB:Q12860] synonym: "Neural cell surface protein F3" EXACT [UniProtKB:Q12860] xref: EMBL:AAA67920.1 xref: EMBL:AAA67921.1 xref: EMBL:AAH36569.1 xref: EMBL:BAF82233.1 xref: EMBL:BAF82387.1 xref: EMBL:CAA79696.1 xref: UniProtKB:A8K0H9 xref: UniProtKB:A8K0Y3 xref: UniProtKB:Q12860 xref: UniProtKB:Q12861 xref: UniProtKB:Q14030 xref: UniProtKB:Q7M4P0 xref: UniProtKB:Q8N466 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017414 ! CNTN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0055852 name: TCF15_HUMAN def: "Transcription factor 15" [UniProtKB:Q12870] synonym: "bHLH-EC2 protein" EXACT [UniProtKB:Q12870] synonym: "Paraxis" EXACT [UniProtKB:Q12870] xref: EMBL:AAA19969.1 xref: EMBL:CAC00470.1 xref: UniProtKB:Q12870 xref: UniProtKB:Q9NQQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020212 ! TCF15_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055853 name: SFRS8_HUMAN def: "Splicing factor, arginine/serine-rich 8" [UniProtKB:Q12872] synonym: "Suppressor of white apricot protein homolog" EXACT [UniProtKB:Q12872] xref: EMBL:AAA19604.1 xref: EMBL:AAH08707.1 xref: EMBL:AAH15953.1 xref: UniProtKB:Q12872 xref: UniProtKB:Q6PJF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019878 ! SFRS8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070436 ! SFRS8_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0070437 ! SFRS8_HUMAN-Phosphoserine604 relationship: transforms_into CCO:B0070438 ! SFRS8_HUMAN-Phosphothreonine642 relationship: transforms_into CCO:B0070439 ! SFRS8_HUMAN-Phosphoserine834 relationship: transforms_into CCO:B0070440 ! SFRS8_HUMAN-Phosphoserine866 relationship: transforms_into CCO:B0070441 ! SFRS8_HUMAN-Phosphoserine870 relationship: transforms_into CCO:B0070442 ! SFRS8_HUMAN-Phosphoserine909 [Term] id: CCO:B0055854 name: ZN155_HUMAN def: "Zinc finger protein 155" [UniProtKB:Q12901] xref: EMBL:AAC50268.1 xref: EMBL:AAF04102.1 xref: EMBL:AAF18684.1 xref: EMBL:AAH75050.1 xref: EMBL:AAH75051.1 xref: EMBL:AAI26378.1 xref: EMBL:AAI30382.1 xref: UniProtKB:A2BDE6 xref: UniProtKB:Q12901 xref: UniProtKB:Q6AZZ8 xref: UniProtKB:Q9UIE1 xref: UniProtKB:Q9UK14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020633 ! ZNF155_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055855 name: ILF2_HUMAN def: "Interleukin enhancer-binding factor 2" [UniProtKB:Q12905] synonym: "Nuclear factor of activated T-cells 45 kDa" EXACT [UniProtKB:Q12905] xref: EMBL:AAA20993.1 xref: EMBL:AAF29591.1 xref: EMBL:AAH00382.1 xref: EMBL:AAM45141.1 xref: EMBL:CAI13610.1 xref: EMBL:CAI13611.1 xref: EMBL:CAI13612.1 xref: EMBL:CAI18796.1 xref: EMBL:EAW53286.1 xref: UniProtKB:A6NDB0 xref: UniProtKB:Q12905 xref: UniProtKB:Q5SR10 xref: UniProtKB:Q5SR11 xref: UniProtKB:Q7L7R3 xref: UniProtKB:Q9BWD4 xref: UniProtKB:Q9P1N0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018273 ! ILF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0015491 ! eef1g-ilf2 physical interaction relationship: participates_in CCO:I0016780 ! nfkb2-q12905 physical interaction relationship: participates_in CCO:I0016839 ! map3k14-q12905 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067083 ! ILF2_HUMAN-Phosphothreonine388 [Term] id: CCO:B0055856 name: PTPRJ_HUMAN def: "Receptor-type tyrosine-protein phosphatase eta precursor" [UniProtKB:Q12913] synonym: "CD148 antigen" EXACT [UniProtKB:Q12913] synonym: "Density-enhanced phosphatase 1" EXACT [UniProtKB:Q12913] synonym: "DEP-1" EXACT [UniProtKB:Q12913] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q12913] synonym: "HPTP eta" EXACT [UniProtKB:Q12913] synonym: "Protein-tyrosine phosphatase eta" EXACT [UniProtKB:Q12913] synonym: "Protein-tyrosine phosphatase receptor type J" EXACT [UniProtKB:Q12913] synonym: "R-PTP-eta" EXACT [UniProtKB:Q12913] xref: EMBL:AAB36687.1 xref: EMBL:AAM69432.1 xref: EMBL:BAA07035.1 xref: UniProtKB:Q12913 xref: UniProtKB:Q15255 xref: UniProtKB:Q8NHM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019552 ! PTPRJ_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001339 ! transmembrane receptor protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0055857 name: KLRB1_HUMAN def: "Killer cell lectin-like receptor subfamily B member 1" [UniProtKB:Q12918] synonym: "C-type lectin domain family 5 member B" EXACT [UniProtKB:Q12918] synonym: "CD161 antigen" EXACT [UniProtKB:Q12918] synonym: "HNKR-P1a" EXACT [UniProtKB:Q12918] synonym: "Natural killer cell surface protein P1A" EXACT [UniProtKB:Q12918] synonym: "NKR-P1A" EXACT [UniProtKB:Q12918] xref: EMBL:AAA21605.1 xref: EMBL:AAI13998.1 xref: EMBL:AAI14517.1 xref: UniProtKB:Q12918 xref: UniProtKB:Q24K24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018427 ! KLRB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0055858 name: ELAV2_HUMAN def: "ELAV-like protein 2" [UniProtKB:Q12926] synonym: "ELAV-like neuronal protein 1" EXACT [UniProtKB:Q12926] synonym: "Hu-antigen B" EXACT [UniProtKB:Q12926] synonym: "HuB" EXACT [UniProtKB:Q12926] synonym: "Nervous system-specific RNA-binding protein Hel-N1" EXACT [UniProtKB:Q12926] xref: EMBL:AAA69698.1 xref: EMBL:AAA70417.1 xref: EMBL:AAH30692.1 xref: EMBL:BAD92531.1 xref: EMBL:CAC22160.1 xref: EMBL:CAI13376.1 xref: UniProtKB:Q12926 xref: UniProtKB:Q13235 xref: UniProtKB:Q59G15 xref: UniProtKB:Q8NEM4 xref: UniProtKB:Q9H1Q8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017681 ! ELAVL2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000314 ! mRNA 3'-UTR binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064973 ! ELAV2_HUMAN-Phosphoserine221 [Term] id: CCO:B0055859 name: NFAC3_HUMAN def: "Nuclear factor of activated T-cells, cytoplasmic 3" [UniProtKB:Q12968] synonym: "NF-AT4" EXACT [UniProtKB:Q12968] synonym: "NF-ATc3" EXACT [UniProtKB:Q12968] synonym: "NFATc3" EXACT [UniProtKB:Q12968] synonym: "NFATx" EXACT [UniProtKB:Q12968] synonym: "T-cell transcription factor NFAT4" EXACT [UniProtKB:Q12968] xref: EMBL:AAA79174.1 xref: EMBL:AAA86308.1 xref: EMBL:AAB46595.1 xref: EMBL:AAB46596.1 xref: EMBL:AAB46597.1 xref: EMBL:AAH01050.1 xref: UniProtKB:O75211 xref: UniProtKB:Q12968 xref: UniProtKB:Q14516 xref: UniProtKB:Q99840 xref: UniProtKB:Q99841 xref: UniProtKB:Q99842 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018767 ! NFATC3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055860 name: PP1R8_HUMAN def: "Nuclear inhibitor of protein phosphatase 1" [UniProtKB:Q12972] synonym: "NIPP-1" EXACT [UniProtKB:Q12972] synonym: "Protein phosphatase 1 regulatory inhibitor subunit 8" EXACT [UniProtKB:Q12972] xref: EMBL:AAA64749.1 xref: EMBL:AAD22486.1 xref: EMBL:AAD24669.1 xref: EMBL:AAD24670.1 xref: EMBL:AAD31541.1 xref: EMBL:AAD31542.1 xref: EMBL:AAH01597.1 xref: EMBL:AAH13360.1 xref: EMBL:CAI20577.1 xref: EMBL:CAI21780.1 xref: UniProtKB:Q12972 xref: UniProtKB:Q5TIF2 xref: UniProtKB:Q6PKF6 xref: UniProtKB:Q9UBH1 xref: UniProtKB:Q9UBZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019476 ! PPP1R8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020120 ! ppp1r8-c14orf1 physical interaction relationship: participates_in CCO:I0020121 ! ppp1r8-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020122 ! ppp1r8-gbp2 physical interaction relationship: participates_in CCO:I0020123 ! ppp1r8-stc2 physical interaction relationship: participates_in CCO:I0020408 ! ppp1r8-crmp1 physical interaction relationship: participates_in CCO:I0020409 ! ppp1r8-setdb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069452 ! PP1R8_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0069453 ! PP1R8_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0069454 ! PP1R8_HUMAN-Phosphotyrosine264 relationship: transforms_into CCO:B0069455 ! PP1R8_HUMAN-Phosphotyrosine335 [Term] id: CCO:B0055861 name: ABR_HUMAN def: "Active breakpoint cluster region-related protein" [UniProtKB:Q12979] xref: EMBL:AAC37518.1 xref: EMBL:AAC37519.1 xref: EMBL:AAC50063.1 xref: UniProtKB:Q12979 xref: UniProtKB:Q13693 xref: UniProtKB:Q13694 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016876 ! ABR_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015911 ! adra1a-abr-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0055862 name: SEC20_HUMAN def: "Vesicle transport protein SEC20" [UniProtKB:Q12981] synonym: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 1" EXACT [UniProtKB:Q12981] synonym: "Transformation-related gene 8 protein" EXACT [UniProtKB:Q12981] synonym: "TRG-8" EXACT [UniProtKB:Q12981] xref: EMBL:AAC00020.1 xref: EMBL:AAC33124.1 xref: EMBL:AAC33125.1 xref: EMBL:AAC33126.1 xref: EMBL:AAH10959.1 xref: EMBL:AAO61090.1 xref: EMBL:AAO91805.1 xref: UniProtKB:O75622 xref: UniProtKB:O75623 xref: UniProtKB:O75624 xref: UniProtKB:Q12981 xref: UniProtKB:Q6K044 xref: UniProtKB:Q96FG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019862 ! BNIP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: located_in CCO:C0001141 ! SNARE complex relationship: located_in CCO:C0002129 ! intracellular membrane-bounded organelle relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0055863 name: NFX1_HUMAN def: "Transcriptional repressor NF-X1" [UniProtKB:Q12986] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q12986] synonym: "Nuclear transcription factor, X box-binding protein 1" EXACT [UniProtKB:Q12986] xref: EMBL:AAA69517.1 xref: EMBL:AAH12151.1 xref: EMBL:AAK16545.1 xref: EMBL:BAF84332.1 xref: EMBL:CAH72745.1 xref: EMBL:CAH72746.1 xref: EMBL:CAH72747.3 xref: EMBL:CAI13304.1 xref: EMBL:CAI13305.1 xref: EMBL:EAW58510.1 xref: EMBL:EAW58511.1 xref: UniProtKB:A8K6H8 xref: UniProtKB:Q12986 xref: UniProtKB:Q5VXW6 xref: UniProtKB:Q96EL5 xref: UniProtKB:Q9BXI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018781 ! NFX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068691 ! NFX1_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0068692 ! NFX1_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0068693 ! NFX1_HUMAN-Phosphotyrosine1041 [Term] id: CCO:B0055864 name: TSN31_HUMAN def: "Tetraspanin-31" [UniProtKB:Q12999] synonym: "Sarcoma-amplified sequence" EXACT [UniProtKB:Q12999] synonym: "Tspan-31" EXACT [UniProtKB:Q12999] xref: EMBL:AAA17782.1 xref: EMBL:AAC39524.2 xref: EMBL:AAH10377.1 xref: UniProtKB:O00577 xref: UniProtKB:Q12999 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020374 ! TSPAN31_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055865 name: TIAM1_HUMAN def: "T-lymphoma invasion and metastasis-inducing protein 1" [UniProtKB:Q13009] synonym: "TIAM-1" EXACT [UniProtKB:Q13009] xref: EMBL:AAA98443.1 xref: EMBL:AAI17193.1 xref: EMBL:AAI17197.1 xref: UniProtKB:Q13009 xref: UniProtKB:Q17RT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020260 ! TIAM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0071396 ! TIAM1_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0071397 ! TIAM1_HUMAN-Phosphotyrosine1323 [Term] id: CCO:B0055866 name: BAK2_HUMAN def: "Putative Bcl-2 homologous antagonist/killer 2" [UniProtKB:Q13014] synonym: "Apoptosis regulator BAK-2" EXACT [UniProtKB:Q13014] xref: EMBL:AAA74467.1 xref: UniProtKB:Q13014 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017123 ! BCL2L7P1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0055867 name: Q13027_HUMAN def: "Growth hormone-releasing hormone receptor form c" [UniProtKB:Q13027] xref: EMBL:AAB18631.1 xref: UniProtKB:Q13027 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055868 name: PRDM2_HUMAN def: "PR domain zinc finger protein 2" [UniProtKB:Q13029] synonym: "GATA-3-binding protein G3B" EXACT [UniProtKB:Q13029] synonym: "Lysine N-methyltransferase 8" EXACT [UniProtKB:Q13029] synonym: "MTB-ZF" EXACT [UniProtKB:Q13029] synonym: "MTE-binding protein" EXACT [UniProtKB:Q13029] synonym: "PR domain-containing protein 2" EXACT [UniProtKB:Q13029] synonym: "Retinoblastoma protein-interacting zinc finger protein" EXACT [UniProtKB:Q13029] synonym: "Zinc finger protein RIZ" EXACT [UniProtKB:Q13029] xref: EMBL:AAA87023.1 xref: EMBL:AAC50820.2 xref: EMBL:BAA08110.1 xref: EMBL:CAH70943.1 xref: EMBL:CAI19343.1 xref: UniProtKB:Q13029 xref: UniProtKB:Q13149 xref: UniProtKB:Q14550 xref: UniProtKB:Q5VUL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019494 ! PRDM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069490 ! PRDM2_HUMAN-Phosphothreonine641 relationship: transforms_into CCO:B0069491 ! PRDM2_HUMAN-Phosphoserine643 relationship: transforms_into CCO:B0069492 ! PRDM2_HUMAN-Phosphoserine739 relationship: transforms_into CCO:B0069493 ! PRDM2_HUMAN-Phosphoserine743 [Term] id: CCO:B0055869 name: FLII_HUMAN def: "Protein flightless-1 homolog" [UniProtKB:Q13045] xref: EMBL:AAC02796.1 xref: EMBL:AAC03568.1 xref: EMBL:AAH25300.1 xref: UniProtKB:Q13045 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017812 ! FLII_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0020002 ! flii-dlst physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066206 ! FLII_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0066207 ! FLII_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0066208 ! FLII_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0066209 ! FLII_HUMAN-Phosphoserine856 [Term] id: CCO:B0055870 name: BIRC1_HUMAN def: "Baculoviral IAP repeat-containing protein 1" [UniProtKB:Q13075] synonym: "Neuronal apoptosis inhibitory protein" EXACT [UniProtKB:Q13075] xref: EMBL:AAA64504.1 xref: EMBL:AAC52045.1 xref: EMBL:AAC52047.1 xref: EMBL:AAC62261.1 xref: EMBL:BAD92360.1 xref: UniProtKB:O75857 xref: UniProtKB:Q13075 xref: UniProtKB:Q13730 xref: UniProtKB:Q59GI6 xref: UniProtKB:Q99796 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017158 ! NAIP_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0055871 name: RM28_HUMAN def: "39S ribosomal protein L28, mitochondrial precursor" [UniProtKB:Q13084] synonym: "L28mt" EXACT [UniProtKB:Q13084] synonym: "Melanoma antigen p15" EXACT [UniProtKB:Q13084] synonym: "Melanoma-associated antigen recognized by T lymphocytes" EXACT [UniProtKB:Q13084] synonym: "MRP-L28" EXACT [UniProtKB:Q13084] xref: EMBL:AAC50181.1 xref: EMBL:AAH00507.2 xref: EMBL:AAH00990.2 xref: EMBL:AAK61226.1 xref: EMBL:AAP88859.1 xref: EMBL:CAI95594.1 xref: UniProtKB:Q13084 xref: UniProtKB:Q4TT39 xref: UniProtKB:Q96S26 xref: UniProtKB:Q9BQD8 xref: UniProtKB:Q9BR04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019754 ! MRPL28_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0006094 ! translation regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000344 ! mitochondrial ribosome relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0020490 ! tubb4-mrpl28 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055872 name: LCP2_HUMAN def: "Lymphocyte cytosolic protein 2" [UniProtKB:Q13094] synonym: "SH2 domain-containing leukocyte protein of 76 kDa" EXACT [UniProtKB:Q13094] synonym: "SLP-76 tyrosine phosphoprotein" EXACT [UniProtKB:Q13094] synonym: "SLP76" EXACT [UniProtKB:Q13094] xref: EMBL:AAC50135.1 xref: EMBL:AAH16618.1 xref: UniProtKB:Q13094 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018465 ! LCP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015853 ! grap2-lcp2 physical interaction relationship: participates_in CCO:I0018434 ! hck-lcp2-1 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0067601 ! LCP2_HUMAN-Phosphotyrosine23 relationship: transforms_into CCO:B0067602 ! LCP2_HUMAN-Phosphotyrosine173 relationship: transforms_into CCO:B0067603 ! LCP2_HUMAN-Phosphoserine207 [Term] id: CCO:B0055873 name: IFT88_HUMAN def: "Intraflagellar transport protein 88 homolog" [UniProtKB:Q13099] synonym: "Recessive polycystic kidney disease protein Tg737 homolog" EXACT [UniProtKB:Q13099] synonym: "Tetratricopeptide repeat protein 10" EXACT [UniProtKB:Q13099] synonym: "TPR repeat protein 10" EXACT [UniProtKB:Q13099] xref: EMBL:AAA86720.1 xref: EMBL:AAH30776.2 xref: EMBL:CAH70874.2 xref: EMBL:CAI14390.2 xref: EMBL:CAM13405.1 xref: EMBL:CAM20430.1 xref: UniProtKB:A2A491 xref: UniProtKB:Q13099 xref: UniProtKB:Q5SZJ6 xref: UniProtKB:Q8N719 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018236 ! IFT88_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000482 ! axoneme relationship: located_in CCO:C0000484 ! basal body relationship: located_in CCO:C0000896 ! flagellum relationship: participates_in CCO:I0018467 ! bat2-tg737 physical interaction relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0002579 ! positive regulation of proteolysis [Term] id: CCO:B0055874 name: TRAF3_HUMAN def: "TNF receptor-associated factor 3" [UniProtKB:Q13114] synonym: "CAP-1" EXACT [UniProtKB:Q13114] synonym: "CD40 receptor-associated factor 1" EXACT [UniProtKB:Q13114] synonym: "CD40-binding protein" EXACT [UniProtKB:Q13114] synonym: "CD40BP" EXACT [UniProtKB:Q13114] synonym: "CRAF1" EXACT [UniProtKB:Q13114] synonym: "LAP1" EXACT [UniProtKB:Q13114] synonym: "LMP1-associated protein" EXACT [UniProtKB:Q13114] xref: EMBL:AAA56753.1 xref: EMBL:AAA65732.1 xref: EMBL:AAA68195.1 xref: EMBL:AAC50112.1 xref: EMBL:AAD29276.1 xref: EMBL:AAH75086.1 xref: EMBL:AAH75087.1 xref: EMBL:CAD62311.1 xref: UniProtKB:Q12990 xref: UniProtKB:Q13076 xref: UniProtKB:Q13114 xref: UniProtKB:Q13947 xref: UniProtKB:Q6AZX1 xref: UniProtKB:Q9UNL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020340 ! TRAF3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015932 ! edar-traf3 physical interaction relationship: participates_in CCO:I0016270 ! cd40-traf3-2 physical interaction relationship: participates_in CCO:I0016842 ! map3k14-traf3 physical interaction relationship: participates_in CCO:I0017224 ! tank-traf3 physical interaction relationship: participates_in CCO:I0017418 ! tank-traf3-1 direct interaction relationship: participates_in CCO:I0017419 ! tank-traf3-2 direct interaction relationship: participates_in CCO:I0017704 ! cd40-traf3-1 physical interaction relationship: participates_in CCO:I0018181 ! hvem-traf3 physical interaction relationship: participates_in CCO:I0018793 ! xedar-traf3 physical interaction relationship: participates_in CCO:I0019495 ! cd40-traf3 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0055875 name: KLF10_HUMAN def: "Krueppel-like factor 10" [UniProtKB:Q13118] synonym: "EGR-alpha" EXACT [UniProtKB:Q13118] synonym: "TGFB-inducible early growth response protein 1" EXACT [UniProtKB:Q13118] synonym: "TIEG-1" EXACT [UniProtKB:Q13118] synonym: "Transforming growth factor-beta-inducible early growth response protein 1" EXACT [UniProtKB:Q13118] xref: EMBL:AAC34293.1 xref: EMBL:AAC50340.1 xref: EMBL:AAH95399.1 xref: UniProtKB:Q13118 xref: UniProtKB:Q503B2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018408 ! KLF10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0067372 ! KLF10_HUMAN-Phosphoserine249 [Term] id: CCO:B0055876 name: REST_HUMAN def: "RE1-silencing transcription factor" [UniProtKB:Q13127] synonym: "Neural-restrictive silencer factor" EXACT [UniProtKB:Q13127] synonym: "X2 box repressor" EXACT [UniProtKB:Q13127] xref: EMBL:AAA98503.1 xref: EMBL:AAB17211.1 xref: EMBL:AAC50114.1 xref: EMBL:AAC50115.1 xref: EMBL:AAH38985.1 xref: EMBL:BAD92987.1 xref: UniProtKB:Q12956 xref: UniProtKB:Q12957 xref: UniProtKB:Q13127 xref: UniProtKB:Q13134 xref: UniProtKB:Q59ER1 xref: UniProtKB:Q8IWI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019677 ! REST_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018532 ! smarce1-rest physical interaction relationship: participates_in CCO:I0018533 ! smarca4-rest physical interaction relationship: participates_in CCO:I0018534 ! smarcc2-rest physical interaction relationship: participates_in CCO:I0018535 ! smarca4-rest-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069884 ! REST_HUMAN-Phosphoserine864 [Term] id: CCO:B0055877 name: RLF_HUMAN def: "Zinc finger protein Rlf" [UniProtKB:Q13129] synonym: "Rearranged L-myc fusion gene protein" EXACT [UniProtKB:Q13129] synonym: "Zn-15-related protein" EXACT [UniProtKB:Q13129] xref: EMBL:AAC50396.1 xref: EMBL:AAI13667.1 xref: EMBL:CAB81608.2 xref: EMBL:CAH71081.1 xref: EMBL:CAI11028.1 xref: EMBL:CAI21999.1 xref: UniProtKB:Q13129 xref: UniProtKB:Q14CQ1 xref: UniProtKB:Q9NU60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019752 ! RLF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018235 ! gch1-rlf-1 physical interaction relationship: participates_in CCO:I0018626 ! gch1-rlf physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070091 ! RLF_HUMAN-Phosphoserine41 [Term] id: CCO:B0055878 name: NR1H3_HUMAN def: "Oxysterols receptor LXR-alpha" [UniProtKB:Q13133] synonym: "Liver X receptor alpha" EXACT [UniProtKB:Q13133] synonym: "Nuclear orphan receptor LXR-alpha" EXACT [UniProtKB:Q13133] synonym: "Nuclear receptor subfamily 1 group H member 3" EXACT [UniProtKB:Q13133] xref: EMBL:AAA85856.1 xref: EMBL:AAH08819.1 xref: UniProtKB:Q13133 xref: UniProtKB:Q96H87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018852 ! NR1H3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017517 ! edf1-nr1h3-4 physical interaction relationship: participates_in CCO:I0018342 ! edf1-nr1h3-3 physical interaction relationship: participates_in CCO:I0018851 ! edf1-nr1h3-2 physical interaction relationship: participates_in CCO:I0019284 ! edf1-nr1h3-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055879 name: EI2BE_HUMAN def: "Translation initiation factor eIF-2B subunit epsilon" [UniProtKB:Q13144] synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon" EXACT [UniProtKB:Q13144] xref: EMBL:AAC50646.1 xref: EMBL:AAH13590.1 xref: UniProtKB:Q13144 xref: UniProtKB:Q96D04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017672 ! EIF2B5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001535 ! negative regulation of translational initiation in response to stress relationship: participates_in CCO:P0002631 ! positive regulation of translational initiation relationship: transforms_into CCO:B0064938 ! EI2BE_HUMAN-Phosphoserine525 relationship: transforms_into CCO:B0064939 ! EI2BE_HUMAN-Phosphoserine527 relationship: transforms_into CCO:B0064940 ! EI2BE_HUMAN-Phosphoserine529 relationship: transforms_into CCO:B0064941 ! EI2BE_HUMAN-Phosphoserine532 relationship: transforms_into CCO:B0064942 ! EI2BE_HUMAN-Phosphoserine535 relationship: transforms_into CCO:B0064943 ! EI2BE_HUMAN-Phosphoserine540 relationship: transforms_into CCO:B0064944 ! EI2BE_HUMAN-Phosphoserine544 relationship: transforms_into CCO:B0064945 ! EI2BE_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0064946 ! EI2BE_HUMAN-Phosphoserine718 [Term] id: CCO:B0055880 name: RFA4_HUMAN def: "Replication protein A 30 kDa subunit" [UniProtKB:Q13156] synonym: "Replication factor A protein 4" EXACT [UniProtKB:Q13156] synonym: "RF-A protein 4" EXACT [UniProtKB:Q13156] synonym: "RP-A p30" EXACT [UniProtKB:Q13156] xref: EMBL:AAB08488.2 xref: EMBL:AAH69791.1 xref: EMBL:AAH69808.1 xref: EMBL:AAH69824.1 xref: EMBL:AAI04014.1 xref: EMBL:AAI04015.1 xref: EMBL:AAM09569.1 xref: EMBL:CAI42256.1 xref: UniProtKB:Q13156 xref: UniProtKB:Q3SY03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019682 ! RPA4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000267 ! DNA replication factor A complex relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000634 ! DNA replication initiation [Term] id: CCO:B0055881 name: FADD_HUMAN def: "Protein FADD" [UniProtKB:Q13158] synonym: "FAS-associated death domain protein" EXACT [UniProtKB:Q13158] synonym: "FAS-associating death domain-containing protein" EXACT [UniProtKB:Q13158] synonym: "Mediator of receptor induced toxicity" EXACT [UniProtKB:Q13158] xref: EMBL:AAA86517.1 xref: EMBL:AAH00334.1 xref: EMBL:AAP35573.1 xref: EMBL:CAA59197.1 xref: UniProtKB:Q13158 xref: UniProtKB:Q14866 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017755 ! FADD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015920 ! tnfrsf6-fadd-1 physical interaction relationship: participates_in CCO:I0015922 ! tnfsf10-tnfrs10b-1 physical interaction relationship: participates_in CCO:I0016112 ! fadd-mbd4 physical interaction relationship: participates_in CCO:I0016113 ! fadd-myd88 physical interaction relationship: participates_in CCO:I0016114 ! fadd-myd88-1 physical interaction relationship: participates_in CCO:I0016251 ! tnfrsf6-fadd-6 physical interaction relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0016253 ! tradd-traf2-2 physical interaction relationship: participates_in CCO:I0016254 ! tnfsf6-tnfrsf6-2 physical interaction relationship: participates_in CCO:I0016255 ! fadd-mbd4-1 physical interaction relationship: participates_in CCO:I0016256 ! mbd4-fadd-1 physical interaction relationship: participates_in CCO:I0017358 ! fadd-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0017360 ! tnfsf10-tnfrs10a-1 physical interaction relationship: participates_in CCO:I0017361 ! tnfsf10-tnfrs10a-3 physical interaction relationship: participates_in CCO:I0017362 ! tnfsf10-tnfrs10b-4 physical interaction relationship: participates_in CCO:I0017498 ! tnfsf10-tnfrs10a-2 physical interaction relationship: participates_in CCO:I0017690 ! tnfrsf6-fadd-14 physical interaction relationship: participates_in CCO:I0017692 ! tnfrsf6-fadd-10 physical interaction relationship: participates_in CCO:I0017694 ! fadd-fadd-2 physical interaction relationship: participates_in CCO:I0017695 ! fadd-fadd-3 physical interaction relationship: participates_in CCO:I0017863 ! tnfrsf6-fadd-2 physical interaction relationship: participates_in CCO:I0017864 ! fadd-fadd-1 physical interaction relationship: participates_in CCO:I0017866 ! tnfrsf6-fadd-5 physical interaction relationship: participates_in CCO:I0017867 ! tnfsf6-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0018016 ! tnfrsf6-fadd-12 physical interaction relationship: participates_in CCO:I0018017 ! tnfrsf6-fadd-13 physical interaction relationship: participates_in CCO:I0018310 ! fadd-mbd4-3 physical interaction relationship: participates_in CCO:I0018609 ! tnfsf10-casp10-1 physical interaction relationship: participates_in CCO:I0018783 ! tnfrsf6-fadd-8 physical interaction relationship: participates_in CCO:I0018784 ! tnfrsf6-fadd-9 physical interaction relationship: participates_in CCO:I0018785 ! fadd-exportin-5 physical interaction relationship: participates_in CCO:I0018786 ! mbd4-fadd physical interaction relationship: participates_in CCO:I0018787 ! fadd-mbd4-2 physical interaction relationship: participates_in CCO:I0018794 ! xedar-fadd physical interaction relationship: participates_in CCO:I0019491 ! tnfsf10-casp10-2 physical interaction relationship: participates_in CCO:I0020411 ! prei3-fadd physical interaction relationship: participates_in CCO:I0020540 ! ddx24-fadd physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0065191 ! FADD_HUMAN-Phosphoserine194 [Term] id: CCO:B0055882 name: PRDX4_HUMAN def: "Peroxiredoxin-4" [UniProtKB:Q13162] synonym: "Antioxidant enzyme AOE372" EXACT [UniProtKB:Q13162] synonym: "AOE37-2" EXACT [UniProtKB:Q13162] synonym: "EC 1.11.1.15" EXACT [UniProtKB:Q13162] synonym: "Prx-IV" EXACT [UniProtKB:Q13162] synonym: "Thioredoxin peroxidase AO372" EXACT [UniProtKB:Q13162] synonym: "Thioredoxin-dependent peroxide reductase A0372" EXACT [UniProtKB:Q13162] xref: EMBL:AAB95175.1 xref: EMBL:AAH03609.1 xref: EMBL:AAH07107.1 xref: EMBL:AAH16770.1 xref: EMBL:CAG46469.1 xref: EMBL:CAG46506.1 xref: UniProtKB:Q13162 xref: UniProtKB:Q6FHT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019504 ! PRDX4_human relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001854 ! thioredoxin peroxidase activity relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0008212 ! peroxiredoxin activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000770 ! I-kappaB phosphorylation [Term] id: CCO:B0055883 name: Q13169_HUMAN def: "Interleukin 2" [UniProtKB:Q13169] xref: EMBL:AAA70092.1 xref: UniProtKB:Q13169 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021086 ! IL2_human relationship: has_function CCO:F0001436 ! interleukin-2 receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0004132 ! kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001254 ! positive regulation of cell growth [Term] id: CCO:B0055884 name: CBX3_HUMAN def: "Chromobox protein homolog 3" [UniProtKB:Q13185] synonym: "HECH" EXACT [UniProtKB:Q13185] synonym: "Heterochromatin protein 1 homolog gamma" EXACT [UniProtKB:Q13185] synonym: "HP1 gamma" EXACT [UniProtKB:Q13185] synonym: "Modifier 2 protein" EXACT [UniProtKB:Q13185] xref: EMBL:AAB48101.1 xref: EMBL:AAF62370.1 xref: EMBL:AAH00954.1 xref: EMBL:AAH14380.1 xref: EMBL:BAA83340.1 xref: UniProtKB:Q13185 xref: UniProtKB:Q96CD7 xref: UniProtKB:Q99409 xref: UniProtKB:Q9BVS3 xref: UniProtKB:Q9P0Z6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017249 ! CBX3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018853 ! cbx3-trim28-2 physical interaction relationship: participates_in CCO:I0019126 ! atxn7l2-cbx3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0064098 ! CBX3_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0064099 ! CBX3_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 [Term] id: CCO:B0055885 name: STK3_HUMAN def: "Serine/threonine-protein kinase 3" [UniProtKB:Q13188] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13188] synonym: "Mammalian STE20-like protein kinase 2" EXACT [UniProtKB:Q13188] synonym: "MST-2" EXACT [UniProtKB:Q13188] synonym: "Serine/threonine-protein kinase Krs-1" EXACT [UniProtKB:Q13188] synonym: "STE20-like kinase MST2" EXACT [UniProtKB:Q13188] xref: EMBL:AAB17261.1 xref: EMBL:AAC50386.1 xref: EMBL:AAH10640.1 xref: EMBL:CAA80909.1 xref: UniProtKB:Q13188 xref: UniProtKB:Q15445 xref: UniProtKB:Q15801 xref: UniProtKB:Q96FM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020070 ! STK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016000 ! stk3-sav1-1 physical interaction relationship: participates_in CCO:I0016002 ! stk3-sav1-2 physical interaction relationship: participates_in CCO:I0018731 ! stk3-sav1-3 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0070975 ! STK3_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0070976 ! STK3_HUMAN-Phosphothreonine180 relationship: transforms_into CCO:B0070977 ! STK3_HUMAN-Phosphoserine316 [Term] id: CCO:B0055886 name: TBX2_HUMAN def: "T-box transcription factor TBX2" [UniProtKB:Q13207] synonym: "T-box protein 2" EXACT [UniProtKB:Q13207] xref: EMBL:AAA73861.1 xref: EMBL:AAB36216.1 xref: EMBL:AAH52566.1 xref: UniProtKB:Q13207 xref: UniProtKB:Q16424 xref: UniProtKB:Q7Z647 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020197 ! TBX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0055887 name: ERCC8_HUMAN def: "DNA excision repair protein ERCC-8" [UniProtKB:Q13216] synonym: "Cockayne syndrome WD repeat protein CSA" EXACT [UniProtKB:Q13216] xref: EMBL:AAA82605.1 xref: EMBL:AAH09793.1 xref: EMBL:AAO21128.1 xref: EMBL:AAV38824.1 xref: EMBL:CAG38800.1 xref: UniProtKB:Q13216 xref: UniProtKB:Q6FHX5 xref: UniProtKB:Q96GB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017725 ! ERCC8_human relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000003 ! nucleotide-excision repair complex relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0018580 ! xab2-ckn1-1 physical interaction relationship: participates_in CCO:I0018581 ! ckn1-xab2-1 physical interaction relationship: participates_in CCO:I0018764 ! xab2-ckn1-2 physical interaction relationship: participates_in CCO:I0020526 ! cbr1-ercc8 physical interaction relationship: participates_in CCO:I0020532 ! ercc8-qp_c physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055888 name: Q13222_HUMAN def: "GATA-4 protein" [UniProtKB:Q13222] xref: EMBL:AAA70335.1 xref: UniProtKB:Q13222 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021087 ! GATA-4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0055889 name: KLRD1_HUMAN def: "Natural killer cells antigen CD94" [UniProtKB:Q13241] synonym: "CD94 antigen" EXACT [UniProtKB:Q13241] synonym: "Killer cell lectin-like receptor subfamily D member 1" EXACT [UniProtKB:Q13241] synonym: "KP43" EXACT [UniProtKB:Q13241] synonym: "NK cell receptor" EXACT [UniProtKB:Q13241] xref: EMBL:AAC50291.1 xref: EMBL:AAH28009.1 xref: EMBL:BAA24450.1 xref: EMBL:BAA24451.1 xref: EMBL:CAA03845.1 xref: EMBL:CAA04230.1 xref: EMBL:CAA74663.1 xref: UniProtKB:O43321 xref: UniProtKB:O43773 xref: UniProtKB:Q13241 xref: UniProtKB:Q9UBE3 xref: UniProtKB:Q9UEQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018428 ! KLRD1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0055890 name: PD2R_HUMAN def: "Prostaglandin D2 receptor" [UniProtKB:Q13258] synonym: "PGD receptor" EXACT [UniProtKB:Q13258] synonym: "Prostanoid DP receptor" EXACT [UniProtKB:Q13258] xref: EMBL:AAC50176.1 xref: EMBL:AAC50177.1 xref: EMBL:AAC50178.1 xref: EMBL:AAH40968.1 xref: UniProtKB:Q13250 xref: UniProtKB:Q13251 xref: UniProtKB:Q13258 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019327 ! PTGDR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000214 ! prostaglandin J receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001298 ! prostaglandin D receptor activity relationship: has_function CCO:F0001301 ! thromboxane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055891 name: I15RA_HUMAN def: "Interleukin-15 receptor subunit alpha precursor" [UniProtKB:Q13261] synonym: "IL-15R-alpha" EXACT [UniProtKB:Q13261] synonym: "IL-15RA" EXACT [UniProtKB:Q13261] xref: EMBL:AAB88175.1 xref: EMBL:AAC50312.1 xref: EMBL:AAH74726.1 xref: EMBL:AAI21141.1 xref: EMBL:AAI21142.1 xref: EMBL:AAP69528.1 xref: EMBL:CAG33345.1 xref: EMBL:CAG46820.1 xref: EMBL:CAI41082.1 xref: UniProtKB:Q13261 xref: UniProtKB:Q5JVA2 xref: UniProtKB:Q6B0J2 xref: UniProtKB:Q7LDR4 xref: UniProtKB:Q7Z609 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018198 ! IL15RA_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001254 ! interleukin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0018381 ! il15-il15ra physical interaction relationship: participates_in CCO:I0018382 ! il15-il15ra-1 physical interaction relationship: participates_in CCO:I0018383 ! il15-il15ra-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055892 name: STF1_HUMAN def: "Steroidogenic factor 1" [UniProtKB:Q13285] synonym: "Adrenal 4-binding protein" EXACT [UniProtKB:Q13285] synonym: "Fushi tarazu factor homolog 1" EXACT [UniProtKB:Q13285] synonym: "Nuclear receptor subfamily 5 group A member 1" EXACT [UniProtKB:Q13285] synonym: "SF-1" EXACT [UniProtKB:Q13285] synonym: "Steroid hormone receptor Ad4BP" EXACT [UniProtKB:Q13285] synonym: "STF-1" EXACT [UniProtKB:Q13285] xref: EMBL:AAA75332.1 xref: EMBL:AAB53105.1 xref: EMBL:AAH32501.1 xref: EMBL:BAA13546.1 xref: UniProtKB:O15196 xref: UniProtKB:Q13285 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020068 ! NR5A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015966 ! edf1-nr5a1-8 colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002962 ! regulation of steroid biosynthetic process relationship: transforms_into CCO:B0070969 ! STF1_HUMAN-N6-acetyllysine34 relationship: transforms_into CCO:B0070970 ! STF1_HUMAN-N6-acetyllysine38 relationship: transforms_into CCO:B0070971 ! STF1_HUMAN-N6-acetyllysine72 relationship: transforms_into CCO:B0070972 ! STF1_HUMAN-Phosphoserine203 [Term] id: CCO:B0055893 name: CLN3_HUMAN def: "Battenin" [UniProtKB:Q13286] synonym: "Batten disease protein" EXACT [UniProtKB:Q13286] synonym: "Protein CLN3" EXACT [UniProtKB:Q13286] xref: EMBL:AAB51075.1 xref: EMBL:AAC05337.1 xref: EMBL:AAC27430.1 xref: EMBL:AAD48543.1 xref: EMBL:AAD51478.1 xref: EMBL:AAD51479.1 xref: EMBL:AAD51480.1 xref: EMBL:AAD51481.1 xref: EMBL:AAD51482.1 xref: EMBL:AAD51483.1 xref: EMBL:AAD51484.1 xref: EMBL:AAD51485.1 xref: EMBL:AAD51487.1 xref: EMBL:AAD51488.1 xref: EMBL:AAD51493.1 xref: EMBL:AAD51494.1 xref: EMBL:AAH02394.1 xref: EMBL:AAH04433.1 xref: EMBL:CAA68148.1 xref: UniProtKB:O00668 xref: UniProtKB:Q13286 xref: UniProtKB:Q9UP09 xref: UniProtKB:Q9UP11 xref: UniProtKB:Q9UP12 xref: UniProtKB:Q9UP13 xref: UniProtKB:Q9UP14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017388 ! CLN3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000376 ! Golgi stack relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: transforms_into CCO:B0064389 ! CLN3_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0064390 ! CLN3_HUMAN-Phosphoserine14 [Term] id: CCO:B0055894 name: SLAF1_HUMAN def: "Signaling lymphocytic activation molecule precursor" [UniProtKB:Q13291] synonym: "CD150 antigen" EXACT [UniProtKB:Q13291] synonym: "CDw150" EXACT [UniProtKB:Q13291] synonym: "IPO-3" EXACT [UniProtKB:Q13291] xref: EMBL:AAA75380.1 xref: UniProtKB:Q13291 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019930 ! SLAMF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0070575 ! SLAF1_HUMAN-Phosphotyrosine281 [Term] id: CCO:B0055895 name: GPR17_HUMAN def: "Uracil nucleotide/cysteinyl leukotriene receptor" [UniProtKB:Q13304] synonym: "G-protein coupled receptor 17" EXACT [UniProtKB:Q13304] synonym: "P2Y-like receptor" EXACT [UniProtKB:Q13304] synonym: "R12" EXACT [UniProtKB:Q13304] synonym: "UDP/CysLT receptor" EXACT [UniProtKB:Q13304] xref: EMBL:AAB16746.1 xref: EMBL:AAH31653.1 xref: EMBL:CAA73144.1 xref: EMBL:CAB08107.1 xref: EMBL:CAB08108.1 xref: UniProtKB:Q13304 xref: UniProtKB:Q8N5S7 xref: UniProtKB:Q9UDZ6 xref: UniProtKB:Q9UE21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018004 ! GPR17_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055896 name: PTK7_HUMAN def: "Tyrosine-protein kinase-like 7 precursor" [UniProtKB:Q13308] synonym: "CCK-4" EXACT [UniProtKB:Q13308] synonym: "Colon carcinoma kinase 4" EXACT [UniProtKB:Q13308] xref: EMBL:AAA87565.1 xref: EMBL:AAC50484.2 xref: EMBL:AAL39062.1 xref: UniProtKB:Q13308 xref: UniProtKB:Q13417 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019545 ! PTK7_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055897 name: GRB10_HUMAN def: "Growth factor receptor-bound protein 10" [UniProtKB:Q13322] synonym: "GRB10 adapter protein" EXACT [UniProtKB:Q13322] synonym: "Insulin receptor-binding protein Grb-IR" EXACT [UniProtKB:Q13322] xref: EMBL:AAA88819.1 xref: EMBL:AAB08431.1 xref: EMBL:AAB81134.1 xref: EMBL:AAC19748.1 xref: EMBL:AAC50671.1 xref: EMBL:AAC83654.1 xref: EMBL:AAC83655.1 xref: EMBL:AAH24285.1 xref: EMBL:BAA13198.2 xref: EMBL:CAB96542.1 xref: UniProtKB:O00427 xref: UniProtKB:O00701 xref: UniProtKB:O75222 xref: UniProtKB:Q13322 xref: UniProtKB:Q92606 xref: UniProtKB:Q92907 xref: UniProtKB:Q92948 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018052 ! GRB10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017303 ! megf10-grb10 physical interaction relationship: participates_in CCO:I0017907 ! ephb1-grb10-3 physical interaction relationship: participates_in CCO:I0018209 ! ephb1-grb10-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0066578 ! GRB10_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0066579 ! GRB10_HUMAN-Phosphoserine150 relationship: transforms_into CCO:B0066580 ! GRB10_HUMAN-Phosphotyrosine404 relationship: transforms_into CCO:B0066581 ! GRB10_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0066582 ! GRB10_HUMAN-Phosphothreonine422 relationship: transforms_into CCO:B0066583 ! GRB10_HUMAN-Phosphoserine431 [Term] id: CCO:B0055898 name: CRFR2_HUMAN def: "Corticotropin-releasing factor receptor 2 precursor" [UniProtKB:Q13324] synonym: "Corticotropin-releasing hormone receptor 2" EXACT [UniProtKB:Q13324] synonym: "CRF-R 2" EXACT [UniProtKB:Q13324] synonym: "CRF2" EXACT [UniProtKB:Q13324] synonym: "CRH-R 2" EXACT [UniProtKB:Q13324] xref: EMBL:AAA91320.1 xref: EMBL:AAB94503.1 xref: EMBL:AAB94562.1 xref: EMBL:AAC71653.1 xref: EMBL:AAC71654.1 xref: EMBL:AAH96830.1 xref: EMBL:AAR18078.1 xref: EMBL:BAC05922.1 xref: EMBL:CAA71235.1 xref: UniProtKB:O43461 xref: UniProtKB:Q13324 xref: UniProtKB:Q4QRJ4 xref: UniProtKB:Q99431 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017455 ! CRHR2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002549 ! corticotrophin-releasing factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:B0055899 name: MTA1_HUMAN def: "Metastasis-associated protein MTA1" [UniProtKB:Q13330] xref: EMBL:AAA78935.1 xref: EMBL:AAH09443.2 xref: EMBL:AAN01613.1 xref: UniProtKB:Q13330 xref: UniProtKB:Q8NFI8 xref: UniProtKB:Q96GI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018670 ! MTA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019853 ! th1l-mta1 physical interaction relationship: participates_in CCO:I0019982 ! ebi2-mta1 physical interaction relationship: participates_in CCO:I0020538 ! ddx18-mta1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068306 ! MTA1_HUMAN-Phosphoserine386 relationship: transforms_into CCO:B0068307 ! MTA1_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0068308 ! MTA1_HUMAN-Phosphothreonine467 relationship: transforms_into CCO:B0068309 ! MTA1_HUMAN-Phosphoserine522 relationship: transforms_into CCO:B0068310 ! MTA1_HUMAN-Phosphothreonine564 relationship: transforms_into CCO:B0068311 ! MTA1_HUMAN-Phosphoserine576 [Term] id: CCO:B0055900 name: KLF1_HUMAN def: "Krueppel-like factor 1" [UniProtKB:Q13351] synonym: "EKLF" EXACT [UniProtKB:Q13351] synonym: "Erythroid krueppel-like transcription factor" EXACT [UniProtKB:Q13351] synonym: "Erythroid transcription factor" EXACT [UniProtKB:Q13351] xref: EMBL:AAB51173.1 xref: EMBL:AAC50562.1 xref: EMBL:AAC51108.1 xref: EMBL:AAH33580.1 xref: UniProtKB:Q13351 xref: UniProtKB:Q6PIJ5 xref: UniProtKB:Q92899 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018416 ! KLF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067378 ! KLF1_HUMAN-Phosphothreonine23 relationship: transforms_into CCO:B0067379 ! KLF1_HUMAN-N6-acetyllysine274 relationship: transforms_into CCO:B0067380 ! KLF1_HUMAN-N6-acetyllysine288 [Term] id: CCO:B0055901 name: ZN177_HUMAN def: "Zinc finger protein 177" [UniProtKB:Q13360] xref: EMBL:AAB09749.1 xref: EMBL:AAH12012.1 xref: UniProtKB:Q13360 xref: UniProtKB:Q96ER2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020640 ! ZNF177_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055902 name: PDE3B_HUMAN def: "cGMP-inhibited 3',5'-cyclic phosphodiesterase B" [UniProtKB:Q13370] synonym: "CGI-PDE B" EXACT [UniProtKB:Q13370] synonym: "CGIP1" EXACT [UniProtKB:Q13370] synonym: "CGIPDE1" EXACT [UniProtKB:Q13370] synonym: "Cyclic GMP-inhibited phosphodiesterase B" EXACT [UniProtKB:Q13370] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q13370] xref: EMBL:AAC50724.1 xref: EMBL:BAA09306.1 xref: EMBL:CAA64774.1 xref: UniProtKB:O00639 xref: UniProtKB:Q13370 xref: UniProtKB:Q14408 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019337 ! PDE3B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002956 ! regulation of insulin secretion relationship: transforms_into CCO:B0069168 ! PDE3B_HUMAN-Phosphoserine442 relationship: transforms_into CCO:B0069169 ! PDE3B_HUMAN-Phosphothreonine444 relationship: transforms_into CCO:B0069170 ! PDE3B_HUMAN-Phosphothreonine625 [Term] id: CCO:B0055903 name: PHLP_HUMAN def: "Phosducin-like protein" [UniProtKB:Q13371] synonym: "PHLP" EXACT [UniProtKB:Q13371] xref: EMBL:AAA79724.1 xref: EMBL:AAD01930.1 xref: EMBL:AAH17227.1 xref: EMBL:CAB56011.1 xref: UniProtKB:Q13371 xref: UniProtKB:Q96AF1 xref: UniProtKB:Q9UEW7 xref: UniProtKB:Q9UFL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019383 ! PDCL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069282 ! PHLP_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0069283 ! PHLP_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0069284 ! PHLP_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0069285 ! PHLP_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0069286 ! PHLP_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0069287 ! PHLP_HUMAN-Phosphoserine296 [Term] id: CCO:B0055904 name: JIP2_HUMAN def: "C-jun-amino-terminal kinase-interacting protein 2" [UniProtKB:Q13387] synonym: "IB-2" EXACT [UniProtKB:Q13387] synonym: "Islet-brain-2" EXACT [UniProtKB:Q13387] synonym: "JIP-2" EXACT [UniProtKB:Q13387] synonym: "JNK MAP kinase scaffold protein 2" EXACT [UniProtKB:Q13387] synonym: "JNK-interacting protein 2" EXACT [UniProtKB:Q13387] synonym: "Mitogen-activated protein kinase 8-interacting protein 2" EXACT [UniProtKB:Q13387] xref: EMBL:AAB03340.1 xref: EMBL:AAB50207.1 xref: EMBL:AAF00980.1 xref: EMBL:AAF32323.1 xref: EMBL:AAH09940.2 xref: EMBL:CAA16714.1 xref: UniProtKB:Q13387 xref: UniProtKB:Q96G62 xref: UniProtKB:Q99771 xref: UniProtKB:Q9NZ59 xref: UniProtKB:Q9UKQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018366 ! MAPK8IP2_human relationship: has_function CCO:F0000136 ! beta-amyloid binding relationship: has_function CCO:F0001384 ! MAP-kinase scaffold activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0004206 ! kinesin binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004382 ! protein kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000714 ! signal complex assembly relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis relationship: participates_in CCO:P0002689 ! regulation of JNK cascade [Term] id: CCO:B0055905 name: TARB1_HUMAN def: "Probable methyltransferase TARBP1" [UniProtKB:Q13395] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q13395] synonym: "TAR RNA-binding protein 1" EXACT [UniProtKB:Q13395] synonym: "TAR RNA-binding protein of 185 kDa" EXACT [UniProtKB:Q13395] synonym: "TRP-185" EXACT [UniProtKB:Q13395] xref: EMBL:AAC50379.1 xref: EMBL:CAI22828.1 xref: EMBL:CAI22931.1 xref: UniProtKB:Q13395 xref: UniProtKB:Q9H581 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020150 ! TARBP1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001760 ! RNA methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055906 name: PM2L3_HUMAN def: "Postmeiotic segregation increased 2-like protein 3" [UniProtKB:Q13401] synonym: "PMS2-related protein 3" EXACT [UniProtKB:Q13401] synonym: "Postmeiotic segregation increased 2-like protein 9" EXACT [UniProtKB:Q13401] synonym: "Postmeiotic segregation increased protein 5" EXACT [UniProtKB:Q13401] xref: EMBL:AAA97459.1 xref: UniProtKB:Q13401 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019453 ! PMS2L3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055907 name: ILK_HUMAN def: "Integrin-linked protein kinase" [UniProtKB:Q13418] synonym: "59 kDa serine/threonine-protein kinase" EXACT [UniProtKB:Q13418] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13418] synonym: "ILK-1" EXACT [UniProtKB:Q13418] synonym: "ILK-2" EXACT [UniProtKB:Q13418] synonym: "p59ILK" EXACT [UniProtKB:Q13418] xref: EMBL:AAC16892.1 xref: EMBL:AAF74449.1 xref: EMBL:AAH01554.1 xref: EMBL:CAB94832.1 xref: EMBL:CAB99253.1 xref: EMBL:CAG28601.1 xref: EMBL:CAH18077.1 xref: UniProtKB:P57043 xref: UniProtKB:Q13418 xref: UniProtKB:Q68DZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018274 ! ILK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0015356 ! ilk-parva physical interaction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055908 name: HAP28_HUMAN def: "28 kDa heat- and acid-stable phosphoprotein" [UniProtKB:Q13442] synonym: "PAP" EXACT [UniProtKB:Q13442] synonym: "PAP1" EXACT [UniProtKB:Q13442] synonym: "PDGF-associated protein" EXACT [UniProtKB:Q13442] synonym: "PDGFA-associated protein 1" EXACT [UniProtKB:Q13442] xref: EMBL:AAB07135.1 xref: EMBL:AAC50462.1 xref: EMBL:AAF03506.1 xref: EMBL:AAH00684.1 xref: EMBL:AAH07873.1 xref: UniProtKB:Q13442 xref: UniProtKB:Q92906 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018104 ! PDAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0066746 ! HAP28_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0066747 ! HAP28_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0066748 ! HAP28_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0066749 ! HAP28_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0066750 ! HAP28_HUMAN-Phosphotyrosine70 relationship: transforms_into CCO:B0066751 ! HAP28_HUMAN-Phosphoserine176 [Term] id: CCO:B0055909 name: TMED1_HUMAN def: "Transmembrane emp24 domain-containing protein 1 precursor" [UniProtKB:Q13445] synonym: "Interleukin-1 receptor-like 1 ligand" EXACT [UniProtKB:Q13445] synonym: "Putative T1/ST2 receptor-binding protein" EXACT [UniProtKB:Q13445] xref: EMBL:AAC50419.1 xref: EMBL:AAD23605.1 xref: EMBL:AAH02443.1 xref: UniProtKB:Q13445 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020289 ! TMED1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055910 name: ROCK1_HUMAN def: "Rho-associated protein kinase 1" [UniProtKB:Q13464] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q13464] synonym: "p160 ROCK-1" EXACT [UniProtKB:Q13464] synonym: "p160ROCK" EXACT [UniProtKB:Q13464] synonym: "Renal carcinoma antigen NY-REN-35" EXACT [UniProtKB:Q13464] synonym: "Rho-associated, coiled-coil-containing protein kinase 1" EXACT [UniProtKB:Q13464] xref: EMBL:AAB02814.1 xref: UniProtKB:Q13464 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019765 ! ROCK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019324 ! rhoa-rock1-1 direct interaction relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0070130 ! ROCK1_HUMAN-Phosphothreonine455 relationship: transforms_into CCO:B0070131 ! ROCK1_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0070132 ! ROCK1_HUMAN-Phosphothreonine1180 [Term] id: CCO:B0055911 name: NFAC2_HUMAN def: "Nuclear factor of activated T-cells, cytoplasmic 2" [UniProtKB:Q13469] synonym: "NF-ATp" EXACT [UniProtKB:Q13469] synonym: "NFAT pre-existing subunit" EXACT [UniProtKB:Q13469] synonym: "T-cell transcription factor NFAT1" EXACT [UniProtKB:Q13469] xref: EMBL:AAC50886.1 xref: EMBL:AAC50887.1 xref: EMBL:CAC00528.2 xref: EMBL:CAI18852.1 xref: EMBL:CAI18853.1 xref: EMBL:CAI19205.1 xref: EMBL:CAI19206.1 xref: EMBL:CAI23549.1 xref: UniProtKB:Q13468 xref: UniProtKB:Q13469 xref: UniProtKB:Q5TFW7 xref: UniProtKB:Q5TFW8 xref: UniProtKB:Q9NPX6 xref: UniProtKB:Q9NQH3 xref: UniProtKB:Q9UJR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018766 ! NFATC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015986 ! foxp3-nfatc2 physical interaction relationship: participates_in CCO:I0015987 ! foxp2-nfatc2-1 physical interaction relationship: participates_in CCO:I0015988 ! foxp1-nfatc2 physical interaction relationship: participates_in CCO:I0018384 ! foxp2-nfatc2 direct interaction relationship: participates_in CCO:I0018878 ! foxp2-nfatc2-2 physical interaction relationship: participates_in CCO:I0020087 ! nfatc2-med31 physical interaction relationship: participates_in CCO:I0020088 ! nfatc2-vim physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0068604 ! NFAC2_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0068605 ! NFAC2_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0068606 ! NFAC2_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0068607 ! NFAC2_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0068608 ! NFAC2_HUMAN-Phosphoserine168 relationship: transforms_into CCO:B0068609 ! NFAC2_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0068610 ! NFAC2_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0068611 ! NFAC2_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0068612 ! NFAC2_HUMAN-Phosphoserine175 relationship: transforms_into CCO:B0068613 ! NFAC2_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0068614 ! NFAC2_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0068615 ! NFAC2_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0068616 ! NFAC2_HUMAN-Phosphoserine217 relationship: transforms_into CCO:B0068617 ! NFAC2_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0068618 ! NFAC2_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0068619 ! NFAC2_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0068620 ! NFAC2_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0068621 ! NFAC2_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0068622 ! NFAC2_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0068623 ! NFAC2_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0068624 ! NFAC2_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0068625 ! NFAC2_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0068626 ! NFAC2_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0068627 ! NFAC2_HUMAN-Phosphothreonine585 relationship: transforms_into CCO:B0068628 ! NFAC2_HUMAN-Phosphothreonine599 relationship: transforms_into CCO:B0068629 ! NFAC2_HUMAN-Phosphoserine605 [Term] id: CCO:B0055912 name: MADCA_HUMAN def: "Mucosal addressin cell adhesion molecule 1 precursor" [UniProtKB:Q13477] synonym: "hMAdCAM-1" EXACT [UniProtKB:Q13477] synonym: "MAdCAM-1" EXACT [UniProtKB:Q13477] xref: EMBL:AAB02194.1 xref: EMBL:AAC13661.1 xref: EMBL:AAC51354.1 xref: EMBL:AAC62844.1 xref: UniProtKB:O60222 xref: UniProtKB:O75867 xref: UniProtKB:Q13477 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018557 ! MADCAM1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055913 name: IL18R_HUMAN def: "Interleukin-18 receptor 1 precursor" [UniProtKB:Q13478] synonym: "CD218 antigen-like family member A" EXACT [UniProtKB:Q13478] synonym: "CD218a antigen" EXACT [UniProtKB:Q13478] synonym: "CDw218a" EXACT [UniProtKB:Q13478] synonym: "IL-1Rrp" EXACT [UniProtKB:Q13478] synonym: "IL1 receptor-related protein" EXACT [UniProtKB:Q13478] xref: EMBL:AAC50390.1 xref: EMBL:AAH69575.1 xref: EMBL:AAH93975.1 xref: EMBL:AAH93977.1 xref: EMBL:AAY15048.1 xref: UniProtKB:Q13478 xref: UniProtKB:Q52LC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018252 ! IL18R1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055914 name: GAB1_HUMAN def: "GRB2-associated-binding protein 1" [UniProtKB:Q13480] synonym: "GRB2-associated binder 1" EXACT [UniProtKB:Q13480] synonym: "Growth factor receptor bound protein 2-associated protein 1" EXACT [UniProtKB:Q13480] xref: EMBL:AAC50380.1 xref: EMBL:AAH64848.1 xref: EMBL:AAY26398.1 xref: EMBL:AAY40964.1 xref: UniProtKB:Q13480 xref: UniProtKB:Q4W5G2 xref: UniProtKB:Q6P1W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017858 ! GAB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017689 ! gab1-ptpn11-2 physical interaction relationship: participates_in CCO:I0017693 ! gab1-pik3r1-2 physical interaction relationship: participates_in CCO:I0017705 ! gab1-ptpn11-1 physical interaction relationship: participates_in CCO:I0017706 ! gab1-pik3r1-1 physical interaction relationship: participates_in CCO:I0018611 ! gab1-ptpn11-3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001257 ! regulation of cell migration relationship: transforms_into CCO:B0066355 ! GAB1_HUMAN-Phosphotyrosine259 relationship: transforms_into CCO:B0066356 ! GAB1_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0066357 ! GAB1_HUMAN-Phosphotyrosine406 relationship: transforms_into CCO:B0066358 ! GAB1_HUMAN-Phosphothreonine503 relationship: transforms_into CCO:B0066359 ! GAB1_HUMAN-Phosphotyrosine627 relationship: transforms_into CCO:B0066360 ! GAB1_HUMAN-Phosphotyrosine659 [Term] id: CCO:B0055915 name: SNPC2_HUMAN def: "snRNA-activating protein complex subunit 2" [UniProtKB:Q13487] synonym: "Proximal sequence element-binding transcription factor subunit delta" EXACT [UniProtKB:Q13487] synonym: "PSE-binding factor subunit delta" EXACT [UniProtKB:Q13487] synonym: "PTF subunit delta" EXACT [UniProtKB:Q13487] synonym: "Small nuclear RNA-activating complex polypeptide 2" EXACT [UniProtKB:Q13487] synonym: "SNAPc 45 kDa subunit" EXACT [UniProtKB:Q13487] synonym: "SNAPc subunit 2" EXACT [UniProtKB:Q13487] synonym: "snRNA-activating protein complex 45 kDa subunit" EXACT [UniProtKB:Q13487] xref: EMBL:AAB06230.1 xref: EMBL:AAC50359.1 xref: EMBL:AAH11868.1 xref: UniProtKB:Q13486 xref: UniProtKB:Q13487 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019965 ! SNAPC2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055916 name: VPP3_HUMAN def: "V-type proton ATPase 116 kDa subunit a isoform 3" [UniProtKB:Q13488] synonym: "OC-116 kDa" EXACT [UniProtKB:Q13488] synonym: "OC116" EXACT [UniProtKB:Q13488] synonym: "Osteoclastic proton pump 116 kDa subunit" EXACT [UniProtKB:Q13488] synonym: "T-cell immune regulator 1" EXACT [UniProtKB:Q13488] synonym: "T-cell immune response cDNA7 protein" EXACT [UniProtKB:Q13488] synonym: "TIRC7" EXACT [UniProtKB:Q13488] synonym: "V-ATPase 116 kDa isoform a3" EXACT [UniProtKB:Q13488] synonym: "Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3" EXACT [UniProtKB:Q13488] xref: EMBL:AAA97878.1 xref: EMBL:AAC35742.1 xref: EMBL:AAD31081.2 xref: UniProtKB:O75877 xref: UniProtKB:Q13488 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020461 ! TCIRG1_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0055917 name: BIRC3_HUMAN def: "Baculoviral IAP repeat-containing protein 3" [UniProtKB:Q13489] synonym: "API2" EXACT [UniProtKB:Q13489] synonym: "Apoptosis inhibitor 2" EXACT [UniProtKB:Q13489] synonym: "C-IAP2" EXACT [UniProtKB:Q13489] synonym: "HIAP-1" EXACT [UniProtKB:Q13489] synonym: "HIAP1" EXACT [UniProtKB:Q13489] synonym: "IAP homolog C" EXACT [UniProtKB:Q13489] synonym: "Inhibitor of apoptosis protein 1" EXACT [UniProtKB:Q13489] synonym: "RING finger protein 49" EXACT [UniProtKB:Q13489] synonym: "TNFR2-TRAF-signaling complex protein 1" EXACT [UniProtKB:Q13489] xref: EMBL:AAC41943.1 xref: EMBL:AAC50371.1 xref: EMBL:AAC50507.1 xref: EMBL:AAC83232.1 xref: EMBL:AAG09369.1 xref: EMBL:AAH37420.1 xref: EMBL:AAU88144.1 xref: UniProtKB:Q13489 xref: UniProtKB:Q16628 xref: UniProtKB:Q9HC27 xref: UniProtKB:Q9UP46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017159 ! BIRC3_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018553 ! birc3-traf2-1 physical interaction relationship: participates_in CCO:I0018554 ! birc3-traf2-3 physical interaction relationship: participates_in CCO:I0018620 ! mihc-diablo physical interaction relationship: participates_in CCO:I0019302 ! birc3-traf2-2 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0055918 name: SQSTM_HUMAN def: "Sequestosome-1" [UniProtKB:Q13501] synonym: "EBI3-associated protein of 60 kDa" EXACT [UniProtKB:Q13501] synonym: "EBIAP" EXACT [UniProtKB:Q13501] synonym: "p60" EXACT [UniProtKB:Q13501] synonym: "Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa" EXACT [UniProtKB:Q13501] synonym: "Ubiquitin-binding protein p62" EXACT [UniProtKB:Q13501] xref: EMBL:AAA93299.1 xref: EMBL:AAC52070.1 xref: EMBL:AAC64516.1 xref: EMBL:AAH00951.1 xref: EMBL:AAH01874.1 xref: EMBL:AAH03139.1 xref: EMBL:AAH17222.1 xref: EMBL:AAH19111.1 xref: UniProtKB:Q13446 xref: UniProtKB:Q13501 xref: UniProtKB:Q9BUV7 xref: UniProtKB:Q9BVS6 xref: UniProtKB:Q9UEU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020032 ! SQSTM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015042 ! gabarapl2-sqstm1 physical interaction relationship: participates_in CCO:I0015251 ! rad23a-sqstm1 physical interaction relationship: participates_in CCO:I0015297 ! gabarapl1-sqstm1 physical interaction relationship: participates_in CCO:I0019428 ! rad23a-sqstm1-1 physical interaction relationship: participates_in CCO:I0019672 ! c14orf139-sqstm1 physical interaction relationship: participates_in CCO:I0019762 ! map1lc3b-sqstm1 physical interaction relationship: participates_in CCO:I0020174 ! sqstm1-sqstm1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002161 ! regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070844 ! SQSTM_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0070845 ! SQSTM_HUMAN-Phosphotyrosine148 relationship: transforms_into CCO:B0070846 ! SQSTM_HUMAN-Phosphoserine170 relationship: transforms_into CCO:B0070847 ! SQSTM_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0070848 ! SQSTM_HUMAN-Phosphoserine207 relationship: transforms_into CCO:B0070849 ! SQSTM_HUMAN-Phosphothreonine269 relationship: transforms_into CCO:B0070850 ! SQSTM_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0070851 ! SQSTM_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0070852 ! SQSTM_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0070853 ! SQSTM_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0070854 ! SQSTM_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0070855 ! SQSTM_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0070856 ! SQSTM_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0070857 ! SQSTM_HUMAN-Phosphoserine366 [Term] id: CCO:B0055919 name: Q13502_HUMAN def: "Phosphotyrosine independent ligand p62B for the Lck SH2 domain B-cell isoform" [UniProtKB:Q13502] xref: EMBL:AAC50535.1 xref: UniProtKB:Q13502 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021088 ! OSIL_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0002161 ! regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0055920 name: NAB1_HUMAN def: "NGFI-A-binding protein 1" [UniProtKB:Q13506] synonym: "EGR-1-binding protein 1" EXACT [UniProtKB:Q13506] synonym: "Transcriptional regulatory protein p54" EXACT [UniProtKB:Q13506] xref: EMBL:AAC25085.1 xref: EMBL:AAC25086.1 xref: EMBL:AAC28325.1 xref: EMBL:AAC50588.1 xref: EMBL:AAH35724.1 xref: EMBL:AAX93076.1 xref: UniProtKB:O75383 xref: UniProtKB:O75384 xref: UniProtKB:Q13506 xref: UniProtKB:Q6GTU1 xref: UniProtKB:Q9UEV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018707 ! NAB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0068428 ! NAB1_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0068429 ! NAB1_HUMAN-Phosphoserine403 [Term] id: CCO:B0055921 name: OLIG2_HUMAN def: "Oligodendrocyte transcription factor 2" [UniProtKB:Q13516] synonym: "bHLHB1" EXACT [UniProtKB:Q13516] synonym: "Class B basic helix-loop-helix protein 1" EXACT [UniProtKB:Q13516] synonym: "Oligo2" EXACT [UniProtKB:Q13516] synonym: "Protein kinase C-binding protein 2" EXACT [UniProtKB:Q13516] synonym: "Protein kinase C-binding protein RACK17" EXACT [UniProtKB:Q13516] xref: EMBL:AAC72247.1 xref: EMBL:AAF61215.1 xref: EMBL:AAH47511.1 xref: UniProtKB:Q13516 xref: UniProtKB:Q86X04 xref: UniProtKB:Q9NZ14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019043 ! OLIG2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055922 name: Q13518_HUMAN def: "Protein kinase C-binding protein RACK8" [UniProtKB:Q13518] xref: EMBL:AAC72246.1 xref: UniProtKB:Q13518 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0055923 name: PNOC_HUMAN def: "Nociceptin precursor" [UniProtKB:Q13519] xref: EMBL:AAC50651.1 xref: EMBL:AAH34758.1 xref: EMBL:CAA66039.1 xref: EMBL:CAA66040.1 xref: UniProtKB:Q13519 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019458 ! PNOC_human relationship: has_function CCO:F0000130 ! opioid peptide activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0055924 name: PPR1A_HUMAN def: "Protein phosphatase 1 regulatory subunit 1A" [UniProtKB:Q13522] synonym: "I-1" EXACT [UniProtKB:Q13522] synonym: "IPP-1" EXACT [UniProtKB:Q13522] synonym: "Protein phosphatase inhibitor 1" EXACT [UniProtKB:Q13522] xref: EMBL:AAB02402.1 xref: EMBL:AAH22470.1 xref: EMBL:AAL48321.1 xref: EMBL:CAG33284.1 xref: UniProtKB:Q13522 xref: UniProtKB:Q6IB01 xref: UniProtKB:Q8TBJ2 xref: UniProtKB:Q8WWV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019482 ! PPP1R1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069460 ! PPR1A_HUMAN-Phosphothreonine35 [Term] id: CCO:B0055925 name: SERC3_HUMAN def: "Serine incorporator 3" [UniProtKB:Q13530] synonym: "Tumor differentially expressed protein 1" EXACT [UniProtKB:Q13530] xref: EMBL:AAB48858.1 xref: EMBL:AAD22448.1 xref: EMBL:AAD34641.1 xref: EMBL:AAH06088.1 xref: EMBL:CAB09783.1 xref: UniProtKB:O43717 xref: UniProtKB:Q13530 xref: UniProtKB:Q9BR33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019869 ! SERINC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0070377 ! SERC3_HUMAN-Phosphoserine371 [Term] id: CCO:B0055926 name: Q13537_HUMAN def: "Putative transposase" [UniProtKB:Q13537] xref: EMBL:AAB61714.1 xref: UniProtKB:Q13537 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055927 name: 4EBP1_HUMAN def: "Eukaryotic translation initiation factor 4E-binding protein 1" [UniProtKB:Q13541] synonym: "4E-BP1" EXACT [UniProtKB:Q13541] synonym: "eIF4E-binding protein 1" EXACT [UniProtKB:Q13541] synonym: "PHAS-I" EXACT [UniProtKB:Q13541] synonym: "Phosphorylated heat- and acid-stable protein regulated by insulin 1" EXACT [UniProtKB:Q13541] xref: EMBL:AAA62269.1 xref: EMBL:AAH04459.1 xref: EMBL:AAH58073.1 xref: EMBL:AAP35826.1 xref: EMBL:BAB18650.1 xref: EMBL:CAG33050.1 xref: UniProtKB:Q13541 xref: UniProtKB:Q6IBN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016847 ! EIF4EBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015830 ! eif4e-eif4ebp1 physical interaction relationship: participates_in CCO:I0016153 ! eif4e-4ebp1-1 direct interaction relationship: participates_in CCO:I0017647 ! eif4e-4ebp1 physical interaction relationship: participates_in CCO:I0017668 ! eif4el3-eif4ebp1-1 physical interaction relationship: participates_in CCO:I0019215 ! 4ebp1-eif4e physical interaction relationship: participates_in CCO:I0020548 ! eif4ebp1-mvd physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002630 ! negative regulation of translational initiation relationship: transforms_into CCO:B0065201 ! 4EBP1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0065202 ! 4EBP1_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0065203 ! 4EBP1_HUMAN-Phosphothreonine36 relationship: transforms_into CCO:B0065204 ! 4EBP1_HUMAN-Phosphothreonine37 relationship: transforms_into CCO:B0065205 ! 4EBP1_HUMAN-Phosphothreonine41 relationship: transforms_into CCO:B0065206 ! 4EBP1_HUMAN-Phosphothreonine46 relationship: transforms_into CCO:B0065207 ! 4EBP1_HUMAN-Phosphothreonine50 relationship: transforms_into CCO:B0065208 ! 4EBP1_HUMAN-Phosphotyrosine54 relationship: transforms_into CCO:B0065209 ! 4EBP1_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0065210 ! 4EBP1_HUMAN-Phosphothreonine68 relationship: transforms_into CCO:B0065211 ! 4EBP1_HUMAN-Phosphothreonine70 relationship: transforms_into CCO:B0065212 ! 4EBP1_HUMAN-Phosphothreonine77 relationship: transforms_into CCO:B0065213 ! 4EBP1_HUMAN-Phosphothreonine82 relationship: transforms_into CCO:B0065214 ! 4EBP1_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0065215 ! 4EBP1_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0065216 ! 4EBP1_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0065217 ! 4EBP1_HUMAN-Phosphoserine112 [Term] id: CCO:B0055928 name: 4EBP2_HUMAN def: "Eukaryotic translation initiation factor 4E-binding protein 2" [UniProtKB:Q13542] synonym: "4E-BP2" EXACT [UniProtKB:Q13542] synonym: "eIF4E-binding protein 2" EXACT [UniProtKB:Q13542] xref: EMBL:AAA62270.1 xref: EMBL:AAH05057.1 xref: EMBL:AAH50633.1 xref: EMBL:AAP35981.1 xref: UniProtKB:Q13542 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016848 ! EIF4EBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016155 ! eif4e-4ebp2-1 direct interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0001149 ! cAMP-mediated signaling relationship: participates_in CCO:P0002630 ! negative regulation of translational initiation relationship: transforms_into CCO:B0065218 ! 4EBP2_HUMAN-Phosphothreonine37 relationship: transforms_into CCO:B0065219 ! 4EBP2_HUMAN-Phosphothreonine46 relationship: transforms_into CCO:B0065220 ! 4EBP2_HUMAN-Phosphoserine65 [Term] id: CCO:B0055929 name: NDF1_HUMAN def: "Neurogenic differentiation factor 1" [UniProtKB:Q13562] synonym: "NeuroD" EXACT [UniProtKB:Q13562] synonym: "NeuroD1" EXACT [UniProtKB:Q13562] xref: EMBL:AAA79702.1 xref: EMBL:AAA93480.1 xref: EMBL:AAC51318.1 xref: EMBL:AAC83145.1 xref: EMBL:AAH09046.1 xref: EMBL:AAV38536.1 xref: EMBL:AAY24267.1 xref: EMBL:BAA11558.1 xref: EMBL:BAA36519.1 xref: EMBL:BAA76603.1 xref: EMBL:BAA87605.1 xref: UniProtKB:O00343 xref: UniProtKB:Q13340 xref: UniProtKB:Q13562 xref: UniProtKB:Q5U095 xref: UniProtKB:Q96TH0 xref: UniProtKB:Q99455 xref: UniProtKB:Q9UEC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018734 ! NEUROD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000780 ! nitric oxide mediated signal transduction relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002956 ! regulation of insulin secretion relationship: transforms_into CCO:B0068526 ! NDF1_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0068527 ! NDF1_HUMAN-Phosphoserine335 [Term] id: CCO:B0055930 name: TDG_HUMAN def: "G/T mismatch-specific thymine DNA glycosylase" [UniProtKB:Q13569] synonym: "EC 3.2.2.-" EXACT [UniProtKB:Q13569] xref: EMBL:AAC50540.1 xref: EMBL:AAH37557.1 xref: EMBL:AAN16399.1 xref: UniProtKB:Q13569 xref: UniProtKB:Q8IUZ6 xref: UniProtKB:Q8IZM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020220 ! TDG_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001804 ! pyrimidine-specific mismatch base pair DNA N-glycosylase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0004051 ! DNA N-glycosylase activity relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0018473 ! bat1-tdg physical interaction relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0055931 name: ITPK1_HUMAN def: "Inositol-tetrakisphosphate 1-kinase" [UniProtKB:Q13572] synonym: "EC 2.7.1.134" EXACT [UniProtKB:Q13572] synonym: "EC 2.7.1.159" EXACT [UniProtKB:Q13572] synonym: "Inositol 1,3,4-trisphosphate 5/6-kinase" EXACT [UniProtKB:Q13572] synonym: "Inositol-triphosphate 5/6-kinase" EXACT [UniProtKB:Q13572] synonym: "Ins(1,3,4)P(3) 5/6-kinase" EXACT [UniProtKB:Q13572] xref: EMBL:AAC50483.1 xref: EMBL:AAG44835.1 xref: EMBL:AAH03622.1 xref: EMBL:AAH07428.1 xref: EMBL:AAH18192.1 xref: UniProtKB:Q13572 xref: UniProtKB:Q9BTL6 xref: UniProtKB:Q9H2E7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018348 ! ITPK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0005593 ! inositol-1,3,4-trisphosphate 5/6-kinase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006634 ! inositol tetrakisphosphate 1-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055932 name: DGKZ_HUMAN def: "Diacylglycerol kinase zeta" [UniProtKB:Q13574] synonym: "DAG kinase zeta" EXACT [UniProtKB:Q13574] synonym: "DGK-zeta" EXACT [UniProtKB:Q13574] synonym: "Diglyceride kinase zeta" EXACT [UniProtKB:Q13574] synonym: "EC 2.7.1.107" EXACT [UniProtKB:Q13574] xref: EMBL:AAB60859.1 xref: EMBL:AAC50478.1 xref: UniProtKB:O00542 xref: UniProtKB:Q13574 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017573 ! DGKZ_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0020163 ! sat-dgkz physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064755 ! DGKZ_HUMAN-Phosphoserine686 [Term] id: CCO:B0055933 name: GRAP_HUMAN def: "GRB2-related adapter protein" [UniProtKB:Q13588] xref: EMBL:AAC50541.1 xref: EMBL:AAH35856.1 xref: EMBL:AAH63035.1 xref: EMBL:AAV38784.1 xref: EMBL:CAG46739.1 xref: EMBL:CAG46764.1 xref: UniProtKB:Q13588 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018051 ! GRAP_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:B0055934 name: OR2F1_HUMAN def: "Olfactory receptor 2F1" [UniProtKB:Q13607] synonym: "Olfactory receptor-like protein OLF3" EXACT [UniProtKB:Q13607] xref: EMBL:AAB01215.1 xref: EMBL:AAC64376.1 xref: EMBL:AAI04976.1 xref: EMBL:AAK95079.1 xref: EMBL:DAA04613.1 xref: UniProtKB:Q13607 xref: UniProtKB:Q6IFP7 xref: UniProtKB:Q96R49 xref: UniProtKB:Q9UDX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019092 ! OR2F1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055935 name: DNSL3_HUMAN def: "Deoxyribonuclease gamma precursor" [UniProtKB:Q13609] synonym: "Deoxyribonuclease I-like 3" EXACT [UniProtKB:Q13609] synonym: "DNase gamma" EXACT [UniProtKB:Q13609] synonym: "DNase I homolog protein DHP2" EXACT [UniProtKB:Q13609] synonym: "DNase I-like 3" EXACT [UniProtKB:Q13609] synonym: "EC 3.1.21.-" EXACT [UniProtKB:Q13609] synonym: "Liver and spleen DNase" EXACT [UniProtKB:Q13609] synonym: "LS-DNase" EXACT [UniProtKB:Q13609] synonym: "LSD" EXACT [UniProtKB:Q13609] xref: EMBL:AAB63967.1 xref: EMBL:AAC23652.1 xref: EMBL:AAC35752.1 xref: EMBL:AAH15831.1 xref: UniProtKB:O75803 xref: UniProtKB:Q13609 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017599 ! DNASE1L3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000932 ! deoxyribonuclease activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis [Term] id: CCO:B0055936 name: RAB32_HUMAN def: "Ras-related protein Rab-32" [UniProtKB:Q13637] xref: EMBL:AAB02833.1 xref: EMBL:AAB09599.1 xref: EMBL:AAH15061.1 xref: EMBL:AAM21106.1 xref: EMBL:AAV38819.1 xref: EMBL:CAC34968.1 xref: UniProtKB:Q13637 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019588 ! RAB32_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069676 ! RAB32_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0069677 ! RAB32_HUMAN-Phosphoserine71 [Term] id: CCO:B0055937 name: 5HT4R_HUMAN def: "5-hydroxytryptamine receptor 4" [UniProtKB:Q13639] synonym: "5-HT-4" EXACT [UniProtKB:Q13639] synonym: "5-HT4" EXACT [UniProtKB:Q13639] synonym: "Serotonin receptor 4" EXACT [UniProtKB:Q13639] xref: EMBL:AAH74755.1 xref: EMBL:CAA09600.1 xref: EMBL:CAA70002.1 xref: EMBL:CAA70774.1 xref: EMBL:CAA71462.1 xref: EMBL:CAA73107.1 xref: EMBL:CAA73108.1 xref: EMBL:CAA73109.1 xref: EMBL:CAA73911.1 xref: EMBL:CAA88167.1 xref: EMBL:CAB71316.1 xref: EMBL:CAC22248.1 xref: EMBL:CAC22250.1 xref: EMBL:CAC22251.1 xref: UniProtKB:Q13639 xref: UniProtKB:Q96KH9 xref: UniProtKB:Q96KI0 xref: UniProtKB:Q9H199 xref: UniProtKB:Q9NY73 xref: UniProtKB:Q9UBM6 xref: UniProtKB:Q9UBT4 xref: UniProtKB:Q9UE22 xref: UniProtKB:Q9UE23 xref: UniProtKB:Q9UQR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016856 ! HTR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001331 ! serotonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0055938 name: PM2LB_HUMAN def: "Postmeiotic segregation increased 2-like protein 11" [UniProtKB:Q13670] synonym: "PMS2-related protein 6" EXACT [UniProtKB:Q13670] xref: EMBL:AAA97460.1 xref: UniProtKB:Q13670 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019454 ! PMS2L11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0069428 ! PM2LB_HUMAN-Phosphotyrosine10 [Term] id: CCO:B0055939 name: ITA7_HUMAN def: "Integrin alpha-7 precursor" [UniProtKB:Q13683] xref: EMBL:AAB87696.1 xref: EMBL:AAC18968.1 xref: EMBL:AAC39708.1 xref: EMBL:AAC80458.1 xref: EMBL:AAQ89241.1 xref: EMBL:CAA52348.1 xref: EMBL:CAB41534.1 xref: EMBL:CAB41535.1 xref: UniProtKB:O43197 xref: UniProtKB:Q13683 xref: UniProtKB:Q9NY89 xref: UniProtKB:Q9UET0 xref: UniProtKB:Q9UEV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018337 ! ITGA7_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000822 ! regulation of cell shape [Term] id: CCO:B0055940 name: AVR2B_HUMAN def: "Activin receptor type-2B precursor" [UniProtKB:Q13705] synonym: "Activin receptor type IIB" EXACT [UniProtKB:Q13705] synonym: "ACTR-IIB" EXACT [UniProtKB:Q13705] synonym: "EC 2.7.11.30" EXACT [UniProtKB:Q13705] xref: EMBL:AAC64515.1 xref: EMBL:AAH96243.1 xref: EMBL:AAH96244.1 xref: EMBL:AAH99642.1 xref: EMBL:BAA24180.2 xref: EMBL:CAA54671.1 xref: UniProtKB:Q13705 xref: UniProtKB:Q4VAV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017105 ! ACVR2B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity relationship: has_function CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003123 ! activin receptor activity, type II relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003510 ! activin receptor activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001714 ! activin receptor signaling pathway relationship: participates_in CCO:P0001717 ! positive regulation of activin receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002483 ! positive regulation of osteoblast differentiation [Term] id: CCO:B0055941 name: Q13731_HUMAN def: "Angiotensin II receptor" [UniProtKB:Q13731] xref: EMBL:AAC37585.1 xref: UniProtKB:Q13731 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0055942 name: ARFRP_HUMAN def: "ADP-ribosylation factor-related protein 1" [UniProtKB:Q13795] synonym: "ARF-related protein 1" EXACT [UniProtKB:Q13795] synonym: "ARP" EXACT [UniProtKB:Q13795] xref: EMBL:AAF35246.1 xref: EMBL:AAH92480.1 xref: EMBL:AAH93967.1 xref: EMBL:AAV38430.1 xref: EMBL:AAV38469.1 xref: EMBL:CAA62804.1 xref: EMBL:CAC03669.1 xref: EMBL:CAG33033.1 xref: UniProtKB:Q13795 xref: UniProtKB:Q6IBQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017011 ! ARFRP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055943 name: ITA9_HUMAN def: "Integrin alpha-9 precursor" [UniProtKB:Q13797] synonym: "Integrin alpha-RLC" EXACT [UniProtKB:Q13797] xref: EMBL:AAA16099.1 xref: EMBL:BAA04984.1 xref: UniProtKB:Q13797 xref: UniProtKB:Q14638 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018339 ! ITGA9_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0055944 name: SPTA2_HUMAN def: "Spectrin alpha chain, brain" [UniProtKB:Q13813] synonym: "Alpha-II spectrin" EXACT [UniProtKB:Q13813] synonym: "Fodrin alpha chain" EXACT [UniProtKB:Q13813] synonym: "Spectrin, non-erythroid alpha chain" EXACT [UniProtKB:Q13813] xref: EMBL:AAA51702.1 xref: EMBL:AAA51790.1 xref: EMBL:AAA52468.1 xref: EMBL:AAB41498.1 xref: EMBL:AAB60364.1 xref: EMBL:AAF26672.1 xref: EMBL:AAH53521.1 xref: EMBL:BAD52438.1 xref: EMBL:BAD93097.1 xref: EMBL:CAA60503.1 xref: EMBL:CAH71404.1 xref: EMBL:CAH71405.1 xref: UniProtKB:Q13186 xref: UniProtKB:Q13813 xref: UniProtKB:Q15324 xref: UniProtKB:Q16606 xref: UniProtKB:Q59EF1 xref: UniProtKB:Q5VXV5 xref: UniProtKB:Q5VXV6 xref: UniProtKB:Q7Z6M5 xref: UniProtKB:Q9P0V0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020023 ! SPTAN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0005975 ! zo_1-actn4 physical interaction relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016471 ! ikbke-sptan1 physical interaction relationship: participates_in CCO:I0016696 ! map3k3-sptan1 physical interaction relationship: participates_in CCO:I0016946 ! q9nyj8-sptan1 physical interaction relationship: participates_in CCO:I0017453 ! disc1-sptan1 physical interaction relationship: participates_in CCO:I0017454 ! disc1-sptan1-1 physical interaction relationship: participates_in CCO:I0017455 ! cep63-sptan1 physical interaction relationship: participates_in CCO:I0017456 ! exoc1-sptan1 physical interaction relationship: participates_in CCO:I0019200 ! spta2-sptb1-2 direct interaction relationship: participates_in CCO:I0019201 ! spta2-sptb1-3 direct interaction relationship: participates_in CCO:I0019202 ! spta2-sptb2-2 direct interaction relationship: participates_in CCO:I0019203 ! spta2-sptb2-3 direct interaction relationship: participates_in CCO:I0019204 ! spta2-sptb2-4 direct interaction relationship: participates_in CCO:I0019205 ! spta2-sptb2-5 direct interaction relationship: participates_in CCO:I0019206 ! spta2-sptb2-6 direct interaction relationship: participates_in CCO:I0019207 ! spta2-sptb2-7 direct interaction relationship: participates_in CCO:I0019967 ! ddx24-sptan1 physical interaction relationship: participates_in CCO:I0020415 ! ptov1-sptan1 physical interaction relationship: participates_in CCO:I0020459 ! sptan1-pin4 physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0070818 ! SPTA2_HUMAN-Phosphoserine1029 relationship: transforms_into CCO:B0070819 ! SPTA2_HUMAN-Phosphoserine1031 relationship: transforms_into CCO:B0070820 ! SPTA2_HUMAN-Phosphotyrosine1176 relationship: transforms_into CCO:B0070821 ! SPTA2_HUMAN-Phosphoserine1217 relationship: transforms_into CCO:B0070822 ! SPTA2_HUMAN-Phosphoserine1323 relationship: transforms_into CCO:B0070823 ! SPTA2_HUMAN-Phosphotyrosine2423 [Term] id: CCO:B0055945 name: ENPP2_HUMAN def: "Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 precursor" [UniProtKB:Q13822] synonym: "Autotaxin" EXACT [UniProtKB:Q13822] synonym: "E-NPP 2" EXACT [UniProtKB:Q13822] synonym: "EC 3.1.4.39" EXACT [UniProtKB:Q13822] synonym: "Extracellular lysophospholipase D" EXACT [UniProtKB:Q13822] synonym: "LysoPLD" EXACT [UniProtKB:Q13822] xref: EMBL:AAA64785.1 xref: EMBL:AAB00855.1 xref: EMBL:AAH34961.1 xref: EMBL:BAA08260.1 xref: EMBL:BAA08342.1 xref: UniProtKB:Q13822 xref: UniProtKB:Q13827 xref: UniProtKB:Q14555 xref: UniProtKB:Q15117 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017715 ! ENPP2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000924 ! phosphodiesterase I activity relationship: has_function CCO:F0000937 ! nucleotide diphosphatase activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006699 ! alkylglycerophosphoethanolamine phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055946 name: TNAP1_HUMAN def: "BTB/POZ domain-containing protein TNFAIP1" [UniProtKB:Q13829] synonym: "Protein B12" EXACT [UniProtKB:Q13829] synonym: "Tumor necrosis factor, alpha-induced protein 1, endothelial" EXACT [UniProtKB:Q13829] xref: EMBL:AAA58385.1 xref: EMBL:AAH01643.1 xref: EMBL:AAH01949.1 xref: EMBL:AAL38649.1 xref: EMBL:CAG33100.1 xref: UniProtKB:Q13829 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020295 ! TNFAIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0071436 ! TNAP1_HUMAN-Phosphoserine278 relationship: transforms_into CCO:B0071437 ! TNAP1_HUMAN-Phosphoserine280 [Term] id: CCO:B0055947 name: PKP1_HUMAN def: "Plakophilin-1" [UniProtKB:Q13835] synonym: "B6P" EXACT [UniProtKB:Q13835] synonym: "Band-6 protein" EXACT [UniProtKB:Q13835] xref: EMBL:CAA55881.1 xref: EMBL:CAA84426.1 xref: EMBL:CAA98022.1 xref: UniProtKB:O00645 xref: UniProtKB:Q13835 xref: UniProtKB:Q15152 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019424 ! PKP1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004137 ! intermediate filament binding relationship: has_function CCO:F0004373 ! structural constituent of epidermis relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000939 ! desmosome relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069373 ! PKP1_HUMAN-Phosphotyrosine214 relationship: transforms_into CCO:B0069374 ! PKP1_HUMAN-Phosphotyrosine499 [Term] id: CCO:B0055948 name: Q13850_HUMAN def: "Peripheral benzodiazepine receptor" [UniProtKB:Q13850] xref: EMBL:AAA18228.1 xref: UniProtKB:Q13850 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001957 ! benzodiazepine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055949 name: KLF9_HUMAN def: "Krueppel-like factor 9" [UniProtKB:Q13886] synonym: "Basic transcription element-binding protein 1" EXACT [UniProtKB:Q13886] synonym: "BTE-binding protein 1" EXACT [UniProtKB:Q13886] synonym: "GC-box-binding protein 1" EXACT [UniProtKB:Q13886] synonym: "Transcription factor BTEB1" EXACT [UniProtKB:Q13886] xref: EMBL:AAD14110.1 xref: EMBL:AAH69431.1 xref: EMBL:AAH74879.1 xref: EMBL:AAH74880.1 xref: EMBL:BAA06524.1 xref: EMBL:CAB99349.1 xref: UniProtKB:Q13886 xref: UniProtKB:Q16196 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018424 ! KLF9_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002965 ! progesterone receptor signaling pathway [Term] id: CCO:B0055950 name: KLF5_HUMAN def: "Krueppel-like factor 5" [UniProtKB:Q13887] synonym: "Basic transcription element-binding protein 2" EXACT [UniProtKB:Q13887] synonym: "BTE-binding protein 2" EXACT [UniProtKB:Q13887] synonym: "Colon krueppel-like factor" EXACT [UniProtKB:Q13887] synonym: "GC-box-binding protein 2" EXACT [UniProtKB:Q13887] synonym: "Intestinal-enriched krueppel-like factor" EXACT [UniProtKB:Q13887] synonym: "Transcription factor BTEB2" EXACT [UniProtKB:Q13887] xref: EMBL:AAF18307.1 xref: EMBL:AAF88068.1 xref: EMBL:AAH07695.1 xref: EMBL:AAH42131.1 xref: EMBL:BAA03393.1 xref: EMBL:BAA96461.1 xref: UniProtKB:Q13887 xref: UniProtKB:Q9UHP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018420 ! KLF5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0055951 name: BT3L2_HUMAN def: "Transcription factor BTF3 homolog 2" [UniProtKB:Q13891] synonym: "Basic transcription factor 3-like 2" EXACT [UniProtKB:Q13891] xref: EMBL:AAB04035.1 xref: UniProtKB:Q13891 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017184 ! BTF3L2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055952 name: C1D_HUMAN def: "Nuclear nucleic acid-binding protein C1D" [UniProtKB:Q13901] synonym: "hC1D" EXACT [UniProtKB:Q13901] xref: EMBL:AAH05235.1 xref: EMBL:AAH09584.1 xref: EMBL:AAH09589.1 xref: EMBL:AAH16284.1 xref: EMBL:AAH17884.1 xref: EMBL:AAX88887.1 xref: EMBL:BAF83140.1 xref: EMBL:CAA64845.1 xref: EMBL:EAW99884.1 xref: UniProtKB:A8K336 xref: UniProtKB:Q05D64 xref: UniProtKB:Q13901 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017193 ! C1D_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000034 ! exosome (RNase complex) relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055953 name: CAYP1_HUMAN def: "Calcyphosin" [UniProtKB:Q13938] synonym: "Calcyphosine" EXACT [UniProtKB:Q13938] xref: EMBL:AAC14484.1 xref: EMBL:AAH80599.1 xref: EMBL:AAI01514.1 xref: EMBL:AAI04767.1 xref: EMBL:CAA66609.1 xref: UniProtKB:Q13938 xref: UniProtKB:Q3MJA7 xref: UniProtKB:Q8WUZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017245 ! CAPS_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064089 ! CAYP1_HUMAN-Phosphoserine40 [Term] id: CCO:B0055954 name: RGRF1_HUMAN def: "Ras-specific guanine nucleotide-releasing factor 1" [UniProtKB:Q13972] synonym: "Guanine nucleotide-releasing factor 1" EXACT [UniProtKB:Q13972] synonym: "Guanine nucleotide-releasing protein" EXACT [UniProtKB:Q13972] synonym: "Ras-GRF1" EXACT [UniProtKB:Q13972] synonym: "Ras-specific nucleotide exchange factor CDC25" EXACT [UniProtKB:Q13972] xref: EMBL:AAA58417.1 xref: EMBL:AAB26881.1 xref: UniProtKB:Q13972 xref: UniProtKB:Q16027 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019699 ! RASGRF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0001006 ! growth cone relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001591 ! positive regulation of Ras GTPase activity relationship: participates_in CCO:P0001690 ! activation of Rac GTPase activity relationship: participates_in CCO:P0001982 ! regulation of Rac protein signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002698 ! regulation of Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0069920 ! RGRF1_HUMAN-Phosphoserine739 [Term] id: CCO:B0055955 name: Q14007_HUMAN def: "C-has/bas p21 protein" [UniProtKB:Q14007] xref: EMBL:AAA35687.1 xref: UniProtKB:Q14007 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0055956 name: RB33A_HUMAN def: "Ras-related protein Rab-33A" [UniProtKB:Q14088] synonym: "Small GTP-binding protein S10" EXACT [UniProtKB:Q14088] xref: EMBL:AAH01157.1 xref: EMBL:AAH09996.1 xref: EMBL:AAM21107.1 xref: EMBL:AAP35687.1 xref: EMBL:BAA03606.1 xref: EMBL:CAI42781.1 xref: UniProtKB:Q14088 xref: UniProtKB:Q5JUZ6 xref: UniProtKB:Q92465 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019636 ! RAB33A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015136 ! rab33a-rabac1 physical interaction relationship: participates_in CCO:I0015559 ! rab33a-rtn3 physical interaction relationship: participates_in CCO:I0015768 ! rab33a-rtn4 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069758 ! RB33A_HUMAN-Cysteine methyl ester237 [Term] id: CCO:B0055957 name: IL18_HUMAN def: "Interleukin-18 precursor" [UniProtKB:Q14116] synonym: "Iboctadekin" EXACT [UniProtKB:Q14116] synonym: "IFN-gamma-inducing factor" EXACT [UniProtKB:Q14116] synonym: "IL-1 gamma" EXACT [UniProtKB:Q14116] synonym: "IL-18" EXACT [UniProtKB:Q14116] synonym: "Interferon-gamma-inducing factor" EXACT [UniProtKB:Q14116] synonym: "Interleukin-1 gamma" EXACT [UniProtKB:Q14116] xref: EMBL:AAB50010.1 xref: EMBL:AAC27787.1 xref: EMBL:AAH07007.1 xref: EMBL:AAH07461.1 xref: EMBL:AAK95950.1 xref: EMBL:BAA08706.1 xref: UniProtKB:O75599 xref: UniProtKB:Q14116 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018253 ! IL18_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001451 ! interleukin-1 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0002043 ! positive regulation of activated T cell proliferation [Term] id: CCO:B0055958 name: VEZF1_HUMAN def: "Vascular endothelial zinc finger 1" [UniProtKB:Q14119] synonym: "Putative transcription factor DB1" EXACT [UniProtKB:Q14119] synonym: "Zinc finger protein 161" EXACT [UniProtKB:Q14119] xref: EMBL:BAA05663.1 xref: UniProtKB:Q14119 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020442 ! VEZF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0055959 name: PDE1C_HUMAN def: "Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C" [UniProtKB:Q14123] synonym: "Cam-PDE 1C" EXACT [UniProtKB:Q14123] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q14123] synonym: "hCam-3" EXACT [UniProtKB:Q14123] xref: EMBL:AAA96961.1 xref: EMBL:AAC50437.1 xref: UniProtKB:Q14123 xref: UniProtKB:Q14124 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019334 ! PDE1C_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000588 ! calmodulin-dependent cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055960 name: VGLL4_HUMAN def: "Transcription cofactor vestigial-like protein 4" [UniProtKB:Q14135] synonym: "Vgl-4" EXACT [UniProtKB:Q14135] xref: EMBL:AAH01514.2 xref: EMBL:AAH03038.1 xref: EMBL:BAA09470.3 xref: EMBL:BAC85375.1 xref: UniProtKB:Q14135 xref: UniProtKB:Q7L5V0 xref: UniProtKB:Q9BQ78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020448 ! VGLL4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071797 ! VGLL4_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0071798 ! VGLL4_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0071799 ! VGLL4_HUMAN-Phosphothreonine153 [Term] id: CCO:B0055961 name: SRTD2_HUMAN def: "SERTA domain-containing protein 2" [UniProtKB:Q14140] synonym: "Transcriptional regulator interacting with the PHD-bromodomain 2" EXACT [UniProtKB:Q14140] synonym: "TRIP-Br2" EXACT [UniProtKB:Q14140] xref: EMBL:AAH74788.1 xref: EMBL:AAH74789.1 xref: EMBL:AAI01640.1 xref: EMBL:AAI01642.1 xref: EMBL:AAY14766.1 xref: EMBL:BAA09476.2 xref: UniProtKB:Q14140 xref: UniProtKB:Q53TS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020040 ! SERTAD2_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0055962 name: KEAP1_HUMAN def: "Kelch-like ECH-associated protein 1" [UniProtKB:Q14145] synonym: "Cytosolic inhibitor of Nrf2" EXACT [UniProtKB:Q14145] synonym: "INrf2" EXACT [UniProtKB:Q14145] synonym: "Kelch-like protein 19" EXACT [UniProtKB:Q14145] xref: EMBL:AAH02417.1 xref: EMBL:AAH02930.1 xref: EMBL:AAH15945.1 xref: EMBL:AAK43722.1 xref: EMBL:AAK51082.1 xref: EMBL:BAA09481.2 xref: UniProtKB:Q14145 xref: UniProtKB:Q6LEP0 xref: UniProtKB:Q9BPY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018400 ! KEAP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002418 ! regulation of epidermal cell differentiation [Term] id: CCO:B0055963 name: MORC3_HUMAN def: "MORC family CW-type zinc finger protein 3" [UniProtKB:Q14149] synonym: "Zinc finger CW-type coiled-coil domain protein 3" EXACT [UniProtKB:Q14149] xref: EMBL:BAA09485.1 xref: EMBL:BAA89432.1 xref: UniProtKB:Q14149 xref: UniProtKB:Q9UEZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018644 ! MORC3_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:P0002783 ! negative regulation of fibroblast proliferation relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0055964 name: SAFB2_HUMAN def: "Scaffold attachment factor B2" [UniProtKB:Q14151] synonym: "SAF-B2" EXACT [UniProtKB:Q14151] xref: EMBL:AAC14666.1 xref: EMBL:AAH25279.1 xref: EMBL:BAA09487.2 xref: UniProtKB:Q14151 xref: UniProtKB:Q8TB13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019831 ! SAFB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0020448 ! safb2-chgb physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070303 ! SAFB2_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0070304 ! SAFB2_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0070305 ! SAFB2_HUMAN-Phosphoserine207 relationship: transforms_into CCO:B0070306 ! SAFB2_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0070307 ! SAFB2_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0070308 ! SAFB2_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0070309 ! SAFB2_HUMAN-Phosphoserine343 relationship: transforms_into CCO:B0070310 ! SAFB2_HUMAN-Phosphoserine513 relationship: transforms_into CCO:B0070311 ! SAFB2_HUMAN-Phosphoserine613 [Term] id: CCO:B0055965 name: EIF3A_HUMAN def: "Eukaryotic translation initiation factor 3 subunit A" [UniProtKB:Q14152] synonym: "eIF-3-theta" EXACT [UniProtKB:Q14152] synonym: "eIF3 p167" EXACT [UniProtKB:Q14152] synonym: "eIF3 p180" EXACT [UniProtKB:Q14152] synonym: "eIF3 p185" EXACT [UniProtKB:Q14152] synonym: "eIF3a" EXACT [UniProtKB:Q14152] synonym: "Eukaryotic translation initiation factor 3 subunit 10" EXACT [UniProtKB:Q14152] xref: EMBL:AAB41584.1 xref: EMBL:AAB41586.1 xref: EMBL:AAB80695.1 xref: EMBL:BAA09488.2 xref: UniProtKB:O00653 xref: UniProtKB:Q14152 xref: UniProtKB:Q15778 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017678 ! EIF3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0064953 ! EIF3A_HUMAN-Phosphotyrosine382 relationship: transforms_into CCO:B0064954 ! EIF3A_HUMAN-Phosphoserine584 relationship: transforms_into CCO:B0064955 ! EIF3A_HUMAN-Phosphoserine1336 [Term] id: CCO:B0055966 name: ARHG7_HUMAN def: "Rho guanine nucleotide exchange factor 7" [UniProtKB:Q14155] synonym: "Beta-Pix" EXACT [UniProtKB:Q14155] synonym: "COOL-1" EXACT [UniProtKB:Q14155] synonym: "p85" EXACT [UniProtKB:Q14155] synonym: "PAK-interacting exchange factor beta" EXACT [UniProtKB:Q14155] xref: EMBL:AAH33905.1 xref: EMBL:AAH50521.1 xref: EMBL:AAH60776.1 xref: EMBL:BAA09763.2 xref: EMBL:BAD66827.1 xref: EMBL:BAE45764.1 xref: EMBL:CAD38906.1 xref: EMBL:CAI12461.1 xref: EMBL:CAI14671.1 xref: EMBL:CAM13628.1 xref: EMBL:CAM20788.1 xref: EMBL:EAX09143.1 xref: UniProtKB:B1ALK6 xref: UniProtKB:B1ALK8 xref: UniProtKB:Q14155 xref: UniProtKB:Q3LIA4 xref: UniProtKB:Q5W9H0 xref: UniProtKB:Q6P9G3 xref: UniProtKB:Q6PII2 xref: UniProtKB:Q86W63 xref: UniProtKB:Q8N3M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017017 ! ARHGEF7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020210 ! tubb4-arhgef7 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0063541 ! ARHG7_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0063542 ! ARHG7_HUMAN-Phosphoserine694 relationship: transforms_into CCO:B0065743 ! ARHG7_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0065744 ! ARHG7_HUMAN-Phosphoserine249 [Term] id: CCO:B0055967 name: GIT2_HUMAN def: "ARF GTPase-activating protein GIT2" [UniProtKB:Q14161] synonym: "CAT-2" EXACT [UniProtKB:Q14161] synonym: "CAT2" EXACT [UniProtKB:Q14161] synonym: "Cool-interacting tyrosine-phosphorylated protein 2" EXACT [UniProtKB:Q14161] synonym: "G protein-coupled receptor kinase-interactor 2" EXACT [UniProtKB:Q14161] synonym: "GRK-interacting protein 2" EXACT [UniProtKB:Q14161] xref: EMBL:AAD28047.1 xref: EMBL:AAH01379.1 xref: EMBL:AAH14223.2 xref: EMBL:AAP35976.1 xref: EMBL:BAA09769.2 xref: UniProtKB:Q14161 xref: UniProtKB:Q86U59 xref: UniProtKB:Q96CI2 xref: UniProtKB:Q9BV91 xref: UniProtKB:Q9Y5V2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017925 ! GIT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0066452 ! GIT2_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0066453 ! GIT2_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0066454 ! GIT2_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0066455 ! GIT2_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0066456 ! GIT2_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0066457 ! GIT2_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0066458 ! GIT2_HUMAN-Phosphotyrosine484 relationship: transforms_into CCO:B0066459 ! GIT2_HUMAN-Phosphothreonine488 relationship: transforms_into CCO:B0066460 ! GIT2_HUMAN-Phosphotyrosine492 relationship: transforms_into CCO:B0066461 ! GIT2_HUMAN-Phosphoserine496 relationship: transforms_into CCO:B0066462 ! GIT2_HUMAN-Phosphoserine559 relationship: transforms_into CCO:B0066463 ! GIT2_HUMAN-Phosphoserine586 relationship: transforms_into CCO:B0066464 ! GIT2_HUMAN-Phosphoserine614 [Term] id: CCO:B0055968 name: MPP2_HUMAN def: "MAGUK p55 subfamily member 2" [UniProtKB:Q14168] synonym: "Discs large homolog 2" EXACT [UniProtKB:Q14168] synonym: "Protein MPP2" EXACT [UniProtKB:Q14168] xref: EMBL:AAH30287.1 xref: EMBL:BAD97280.1 xref: EMBL:CAA58067.1 xref: EMBL:CAB66489.1 xref: EMBL:CAI56746.1 xref: UniProtKB:Q14168 xref: UniProtKB:Q53ES9 xref: UniProtKB:Q5CZB9 xref: UniProtKB:Q9BQJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018648 ! MPP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068260 ! MPP2_HUMAN-Phosphoserine42 [Term] id: CCO:B0055969 name: SIM2_HUMAN def: "Single-minded homolog 2" [UniProtKB:Q14190] xref: EMBL:AAB62396.1 xref: EMBL:AAB62397.1 xref: EMBL:BAA07906.1 xref: EMBL:BAA07907.1 xref: EMBL:BAA07908.1 xref: EMBL:BAA07909.1 xref: EMBL:BAA07910.1 xref: EMBL:BAA11108.1 xref: EMBL:BAA12919.1 xref: EMBL:BAA21489.1 xref: EMBL:BAA21490.1 xref: EMBL:BAA89433.1 xref: EMBL:CAA05055.1 xref: EMBL:CAA59261.1 xref: UniProtKB:O60766 xref: UniProtKB:Q14190 xref: UniProtKB:Q15470 xref: UniProtKB:Q15471 xref: UniProtKB:Q15472 xref: UniProtKB:Q15473 xref: UniProtKB:Q16532 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019909 ! SIM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055970 name: DPYL3_HUMAN def: "Dihydropyrimidinase-related protein 3" [UniProtKB:Q14195] synonym: "Collapsin response mediator protein 4" EXACT [UniProtKB:Q14195] synonym: "CRMP-4" EXACT [UniProtKB:Q14195] synonym: "DRP-3" EXACT [UniProtKB:Q14195] synonym: "ULIP protein" EXACT [UniProtKB:Q14195] synonym: "Unc-33-like phosphoprotein" EXACT [UniProtKB:Q14195] xref: EMBL:BAA11192.1 xref: EMBL:CAA69153.1 xref: UniProtKB:Q14195 xref: UniProtKB:Q93012 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017615 ! DPYSL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017428 ! disc1-dpysl3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064871 ! DPYL3_HUMAN-Phosphotyrosine499 relationship: transforms_into CCO:B0064872 ! DPYL3_HUMAN-Phosphothreonine509 relationship: transforms_into CCO:B0064873 ! DPYL3_HUMAN-Phosphoserine522 relationship: transforms_into CCO:B0064874 ! DPYL3_HUMAN-Phosphoserine551 [Term] id: CCO:B0055971 name: RCAN2_HUMAN def: "Calcipressin-2" [UniProtKB:Q14206] synonym: "Down syndrome candidate region 1-like 1" EXACT [UniProtKB:Q14206] synonym: "MCIP2" EXACT [UniProtKB:Q14206] synonym: "Myocyte-enriched calcineurin-interacting protein 2" EXACT [UniProtKB:Q14206] synonym: "Regulator of calcineurin 2" EXACT [UniProtKB:Q14206] synonym: "Thyroid hormone-responsive protein ZAKI-4" EXACT [UniProtKB:Q14206] xref: EMBL:AAK59805.1 xref: EMBL:AAK59806.1 xref: EMBL:BAA11911.1 xref: EMBL:CAH73259.1 xref: EMBL:CAH73260.1 xref: EMBL:CAI16754.1 xref: EMBL:EAX04294.1 xref: UniProtKB:A6ND07 xref: UniProtKB:Q14206 xref: UniProtKB:Q5VWF7 xref: UniProtKB:Q5VWF8 xref: UniProtKB:Q8N116 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019654 ! RCAN2_human relationship: has_function CCO:F0004400 ! protein phosphatase 2B binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0055972 name: IL27B_HUMAN def: "Interleukin-27 subunit beta precursor" [UniProtKB:Q14213] synonym: "EBV-induced gene 3 protein" EXACT [UniProtKB:Q14213] synonym: "Epstein-Barr virus-induced gene 3 protein" EXACT [UniProtKB:Q14213] synonym: "IL-27 subunit beta" EXACT [UniProtKB:Q14213] synonym: "IL-27B" EXACT [UniProtKB:Q14213] xref: EMBL:AAA93193.1 xref: EMBL:AAC33488.1 xref: EMBL:AAH15364.1 xref: EMBL:AAH46112.1 xref: UniProtKB:O75269 xref: UniProtKB:Q14213 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018260 ! EBI3_human relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004230 ! interleukin binding relationship: has_function CCO:F0006154 ! interleukin-27 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015052 ! ebi3-mdfi physical interaction relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002716 ! positive regulation of alpha-beta T cell proliferation [Term] id: CCO:B0055973 name: EPAG_HUMAN def: "Early lymphoid activation gene protein" [UniProtKB:Q14236] xref: EMBL:AAA20152.1 xref: UniProtKB:Q14236 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017719 ! EPAG_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055974 name: ELOA1_HUMAN def: "Transcription elongation factor B polypeptide 3" [UniProtKB:Q14241] synonym: "EloA" EXACT [UniProtKB:Q14241] synonym: "Elongin 110 kDa subunit" EXACT [UniProtKB:Q14241] synonym: "Elongin-A" EXACT [UniProtKB:Q14241] synonym: "RNA polymerase II transcription factor SIII subunit A1" EXACT [UniProtKB:Q14241] synonym: "SIII p110" EXACT [UniProtKB:Q14241] xref: EMBL:AAA75492.1 xref: EMBL:AAH02883.1 xref: EMBL:AAO15305.1 xref: EMBL:CAB40157.1 xref: UniProtKB:Q14241 xref: UniProtKB:Q8IXH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017693 ! TCEB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0065041 ! ELOA1_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0065042 ! ELOA1_HUMAN-Phosphoserine137 [Term] id: CCO:B0055975 name: EMR1_HUMAN def: "EGF-like module-containing mucin-like hormone receptor-like 1 precursor" [UniProtKB:Q14246] synonym: "Cell surface glycoprotein EMR1" EXACT [UniProtKB:Q14246] synonym: "EMR1 hormone receptor" EXACT [UniProtKB:Q14246] xref: EMBL:AAH59395.1 xref: EMBL:ABB70739.1 xref: EMBL:BAC06133.1 xref: EMBL:CAA57232.1 xref: UniProtKB:A6NHV2 xref: UniProtKB:Q14246 xref: UniProtKB:Q2I7G5 xref: UniProtKB:Q8NGA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017704 ! EMR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0055976 name: FASTK_HUMAN def: "Fas-activated serine/threonine kinase" [UniProtKB:Q14296] synonym: "EC 2.7.11.8" EXACT [UniProtKB:Q14296] synonym: "FAST kinase" EXACT [UniProtKB:Q14296] xref: EMBL:AAH11770.1 xref: EMBL:CAA60448.1 xref: UniProtKB:Q14296 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017765 ! FASTK_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005349 ! Fas-activated serine/threonine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals [Term] id: CCO:B0055977 name: FGL2_HUMAN def: "Fibroleukin precursor" [UniProtKB:Q14314] synonym: "Fibrinogen-like protein 2" EXACT [UniProtKB:Q14314] synonym: "pT49" EXACT [UniProtKB:Q14314] xref: EMBL:AAD10825.1 xref: EMBL:AAH33820.1 xref: EMBL:AAH73986.1 xref: EMBL:AAL68855.1 xref: EMBL:CAA85298.1 xref: UniProtKB:Q14314 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017803 ! FGL2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0055978 name: FKBP8_HUMAN def: "FK506-binding protein 8" [UniProtKB:Q14318] synonym: "38 kDa FK506-binding protein" EXACT [UniProtKB:Q14318] synonym: "EC 5.2.1.8" EXACT [UniProtKB:Q14318] synonym: "FKBPR38" EXACT [UniProtKB:Q14318] synonym: "hFKBP38" EXACT [UniProtKB:Q14318] synonym: "Peptidyl-prolyl cis-trans isomerase" EXACT [UniProtKB:Q14318] synonym: "PPIase" EXACT [UniProtKB:Q14318] synonym: "Rotamase" EXACT [UniProtKB:Q14318] xref: EMBL:AAB00102.1 xref: EMBL:AAC28753.1 xref: EMBL:AAH09966.1 xref: EMBL:AAO39020.1 xref: EMBL:AAQ84561.1 xref: EMBL:BAD96558.1 xref: EMBL:CAD98028.1 xref: EMBL:EAW84709.1 xref: UniProtKB:Q14318 xref: UniProtKB:Q53GU3 xref: UniProtKB:Q7Z349 xref: UniProtKB:Q86YK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017810 ! FKBP8_human relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:I0020553 ! fkbp8-mapk14 physical interaction relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0066200 ! FKBP8_HUMAN-Phosphotyrosine322 [Term] id: CCO:B0055979 name: GPR18_HUMAN def: "N-arachidonyl glycine receptor" [UniProtKB:Q14330] synonym: "G-protein coupled receptor 18" EXACT [UniProtKB:Q14330] synonym: "NAGly receptor" EXACT [UniProtKB:Q14330] xref: EMBL:AAB65819.1 xref: EMBL:AAG44671.1 xref: EMBL:AAH08569.1 xref: EMBL:AAH50646.1 xref: EMBL:AAH66927.1 xref: EMBL:AAP88909.1 xref: EMBL:CAI14306.1 xref: UniProtKB:Q14330 xref: UniProtKB:Q6GTM3 xref: UniProtKB:Q96HI6 xref: UniProtKB:Q9H2L2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018005 ! GPR18_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055980 name: Q14333_HUMAN def: "Facioscapulohumeral muscular dystrophy" [UniProtKB:Q14333] xref: EMBL:BAA07227.1 xref: UniProtKB:Q14333 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017641 ! DUX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055981 name: Q14396_HUMAN def: "Liver beta-subunit signal transducing proteins Gs/Gi (beta-G)" [UniProtKB:Q14396] xref: EMBL:CAA28206.1 xref: UniProtKB:Q14396 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055982 name: PDE3A_HUMAN def: "cGMP-inhibited 3',5'-cyclic phosphodiesterase A" [UniProtKB:Q14432] synonym: "CGI-PDE A" EXACT [UniProtKB:Q14432] synonym: "Cyclic GMP-inhibited phosphodiesterase A" EXACT [UniProtKB:Q14432] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q14432] xref: EMBL:AAA35912.2 xref: EMBL:AAB18673.1 xref: EMBL:AAI17370.1 xref: EMBL:AAI17372.1 xref: EMBL:CAA06304.1 xref: UniProtKB:O60865 xref: UniProtKB:Q13348 xref: UniProtKB:Q14432 xref: UniProtKB:Q17RD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019336 ! PDE3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069164 ! PDE3A_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0069165 ! PDE3A_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0069166 ! PDE3A_HUMAN-Phosphothreonine440 relationship: transforms_into CCO:B0069167 ! PDE3A_HUMAN-Phosphoserine495 [Term] id: CCO:B0055983 name: GP176_HUMAN def: "Probable G-protein coupled receptor 176" [UniProtKB:Q14439] synonym: "HB-954" EXACT [UniProtKB:Q14439] xref: EMBL:AAH67106.1 xref: EMBL:BAA07481.1 xref: UniProtKB:Q14439 xref: UniProtKB:Q6NXF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017988 ! GPR176_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0055984 name: GRB14_HUMAN def: "Growth factor receptor-bound protein 14" [UniProtKB:Q14449] synonym: "GRB14 adapter protein" EXACT [UniProtKB:Q14449] xref: EMBL:AAC15861.1 xref: EMBL:AAH53559.1 xref: UniProtKB:Q14449 xref: UniProtKB:Q7Z6I1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018053 ! GRB14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066584 ! GRB14_HUMAN-Phosphoserine372 [Term] id: CCO:B0055985 name: GRB7_HUMAN def: "Growth factor receptor-bound protein 7" [UniProtKB:Q14451] synonym: "B47" EXACT [UniProtKB:Q14451] synonym: "Epidermal growth factor receptor GRB-7" EXACT [UniProtKB:Q14451] synonym: "GRB7 adapter protein" EXACT [UniProtKB:Q14451] xref: EMBL:AAG25938.1 xref: EMBL:AAH06535.1 xref: EMBL:BAA07827.1 xref: EMBL:BAA13412.1 xref: EMBL:BAA29059.1 xref: EMBL:BAA29060.1 xref: UniProtKB:Q14451 xref: UniProtKB:Q92568 xref: UniProtKB:Q96DF9 xref: UniProtKB:Q9Y220 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018054 ! GRB7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: transforms_into CCO:B0066586 ! GRB7_HUMAN-Phosphothreonine297 relationship: transforms_into CCO:B0066587 ! GRB7_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0066588 ! GRB7_HUMAN-Phosphoserine366 [Term] id: CCO:B0055986 name: HES1_HUMAN def: "Transcription factor HES-1" [UniProtKB:Q14469] synonym: "Hairy and enhancer of split 1" EXACT [UniProtKB:Q14469] synonym: "Hairy homolog" EXACT [UniProtKB:Q14469] synonym: "Hairy-like" EXACT [UniProtKB:Q14469] synonym: "HHL" EXACT [UniProtKB:Q14469] xref: EMBL:AAA65220.1 xref: EMBL:AAF73060.1 xref: EMBL:BAA91149.1 xref: UniProtKB:Q14469 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018117 ! HES1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002422 ! negative regulation of auditory receptor cell differentiation relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation relationship: participates_in CCO:P0002851 ! regulation of timing of cell differentiation [Term] id: CCO:B0055987 name: RBM39_HUMAN def: "RNA-binding protein 39" [UniProtKB:Q14498] synonym: "Hepatocellular carcinoma protein 1" EXACT [UniProtKB:Q14498] synonym: "RNA-binding motif protein 39" EXACT [UniProtKB:Q14498] synonym: "RNA-binding region-containing protein 2" EXACT [UniProtKB:Q14498] synonym: "Splicing factor HCC1" EXACT [UniProtKB:Q14498] xref: EMBL:AAA16346.1 xref: EMBL:AAA16347.1 xref: EMBL:AAI41836.1 xref: EMBL:CAC11118.1 xref: EMBL:CAC11119.1 xref: UniProtKB:A5D8W2 xref: UniProtKB:Q14498 xref: UniProtKB:Q14499 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019647 ! RBM39_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069811 ! RBM39_HUMAN-Phosphotyrosine95 relationship: transforms_into CCO:B0069812 ! RBM39_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0069813 ! RBM39_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0069814 ! RBM39_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0069815 ! RBM39_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0069816 ! RBM39_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0069817 ! RBM39_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0069818 ! RBM39_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0069819 ! RBM39_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0069820 ! RBM39_HUMAN-Phosphoserine341 [Term] id: CCO:B0055988 name: Q14501_HUMAN def: "HCREM 1alpha protein" [UniProtKB:Q14501] xref: EMBL:BAA03562.1 xref: UniProtKB:Q14501 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021090 ! hCREM-1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001743 ! cAMP response element binding protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055989 name: HLTF_HUMAN def: "Helicase-like transcription factor" [UniProtKB:Q14527] synonym: "DNA-binding protein/plasminogen activator inhibitor 1 regulator" EXACT [UniProtKB:Q14527] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q14527] synonym: "HIP116" EXACT [UniProtKB:Q14527] synonym: "RING finger protein 80" EXACT [UniProtKB:Q14527] synonym: "Sucrose nonfermenting protein 2-like 3" EXACT [UniProtKB:Q14527] synonym: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3" EXACT [UniProtKB:Q14527] xref: EMBL:AAA67436.1 xref: EMBL:AAB27691.1 xref: EMBL:AAH44659.1 xref: EMBL:CAA86571.1 xref: EMBL:CAA86572.1 xref: EMBL:CAD10805.1 xref: UniProtKB:Q14527 xref: UniProtKB:Q14536 xref: UniProtKB:Q16051 xref: UniProtKB:Q7KYJ6 xref: UniProtKB:Q86YA5 xref: UniProtKB:Q92652 xref: UniProtKB:Q96KM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018136 ! HLTF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0066813 ! HLTF_HUMAN-Phosphothreonine390 relationship: transforms_into CCO:B0066814 ! HLTF_HUMAN-Phosphotyrosine394 relationship: transforms_into CCO:B0066815 ! HLTF_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0066816 ! HLTF_HUMAN-Phosphoserine398 relationship: transforms_into CCO:B0066817 ! HLTF_HUMAN-Phosphoserine400 relationship: transforms_into CCO:B0066818 ! HLTF_HUMAN-Phosphoserine635 relationship: transforms_into CCO:B0066819 ! HLTF_HUMAN-Phosphothreonine736 [Term] id: CCO:B0055990 name: S29A2_HUMAN def: "Equilibrative nucleoside transporter 2" [UniProtKB:Q14542] synonym: "36 kDa nucleolar protein HNP36" EXACT [UniProtKB:Q14542] synonym: "Delayed-early response protein 12" EXACT [UniProtKB:Q14542] synonym: "Equilibrative NBMPR-insensitive nucleoside transporter" EXACT [UniProtKB:Q14542] synonym: "Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter" EXACT [UniProtKB:Q14542] synonym: "Hydrophobic nucleolar protein, 36 kDa" EXACT [UniProtKB:Q14542] synonym: "Nucleoside transporter, ei-type" EXACT [UniProtKB:Q14542] synonym: "Solute carrier family 29 member 2" EXACT [UniProtKB:Q14542] xref: EMBL:AAB97834.1 xref: EMBL:AAC39526.1 xref: EMBL:AAH93634.1 xref: EMBL:CAA60380.1 xref: UniProtKB:O43530 xref: UniProtKB:Q14542 xref: UniProtKB:Q52M84 xref: UniProtKB:Q9UPE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019822 ! SLC29A2_human relationship: has_function CCO:F0001567 ! nucleoside transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0055991 name: Q14547_HUMAN def: "Homeobox-like" [UniProtKB:Q14547] xref: EMBL:AAA83547.1 xref: UniProtKB:Q14547 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055992 name: Q14548_HUMAN def: "HOX2.8 protein" [UniProtKB:Q14548] xref: EMBL:AAB00778.1 xref: UniProtKB:Q14548 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021091 ! HOX2.8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0055993 name: Q14560_HUMAN def: "HPX-42 protein" [UniProtKB:Q14560] xref: EMBL:CAA52857.1 xref: UniProtKB:Q14560 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021092 ! VENTX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055994 name: ITPR2_HUMAN def: "Inositol 1,4,5-trisphosphate receptor type 2" [UniProtKB:Q14571] synonym: "InsP3R2" EXACT [UniProtKB:Q14571] synonym: "IP3 receptor isoform 2" EXACT [UniProtKB:Q14571] synonym: "Type 2 inositol 1,4,5-trisphosphate receptor" EXACT [UniProtKB:Q14571] synonym: "Type 2 InsP3 receptor" EXACT [UniProtKB:Q14571] xref: EMBL:BAA05384.1 xref: EMBL:BAA33961.1 xref: UniProtKB:O94773 xref: UniProtKB:Q14571 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018350 ! ITPR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067169 ! ITPR2_HUMAN-Phosphoserine1160 relationship: transforms_into CCO:B0067170 ! ITPR2_HUMAN-Phosphotyrosine2607 [Term] id: CCO:B0055995 name: ITPR3_HUMAN def: "Inositol 1,4,5-trisphosphate receptor type 3" [UniProtKB:Q14573] synonym: "InsP3R3" EXACT [UniProtKB:Q14573] synonym: "IP3 receptor isoform 3" EXACT [UniProtKB:Q14573] synonym: "Type 3 inositol 1,4,5-trisphosphate receptor" EXACT [UniProtKB:Q14573] synonym: "Type 3 InsP3 receptor" EXACT [UniProtKB:Q14573] xref: EMBL:AAC50064.1 xref: EMBL:BAA05385.1 xref: EMBL:CAI16455.1 xref: EMBL:EAX03744.1 xref: UniProtKB:Q14573 xref: UniProtKB:Q14649 xref: UniProtKB:Q5TAQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018351 ! ITPR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067171 ! ITPR3_HUMAN-Phosphoserine916 relationship: transforms_into CCO:B0067172 ! ITPR3_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0067173 ! ITPR3_HUMAN-Phosphoserine1832 relationship: transforms_into CCO:B0067174 ! ITPR3_HUMAN-Phosphotyrosine2583 relationship: transforms_into CCO:B0067175 ! ITPR3_HUMAN-Phosphoserine2670 [Term] id: CCO:B0055996 name: ZN266_HUMAN def: "Zinc finger protein 266" [UniProtKB:Q14584] synonym: "HZF1" EXACT [UniProtKB:Q14584] synonym: "Zinc finger protein 1" EXACT [UniProtKB:Q14584] xref: EMBL:AAH17407.1 xref: EMBL:AAH71628.1 xref: EMBL:AAI26256.1 xref: EMBL:AAQ82907.1 xref: EMBL:BAB55142.1 xref: EMBL:BAC23104.1 xref: EMBL:CAA55524.1 xref: UniProtKB:A0AV90 xref: UniProtKB:Q14584 xref: UniProtKB:Q6IQ07 xref: UniProtKB:Q6U8A5 xref: UniProtKB:Q8IVG3 xref: UniProtKB:Q8WVX1 xref: UniProtKB:Q96SX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020684 ! ZNF266_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0055997 name: ZN345_HUMAN def: "Zinc finger protein 345" [UniProtKB:Q14585] synonym: "HZF10" EXACT [UniProtKB:Q14585] synonym: "Zinc finger protein 10" EXACT [UniProtKB:Q14585] xref: EMBL:AAH32863.1 xref: EMBL:CAA55533.1 xref: UniProtKB:Q14585 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020716 ! ZNF345_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0000297 ! RNA polymerase III transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter [Term] id: CCO:B0055998 name: ZN267_HUMAN def: "Zinc finger protein 267" [UniProtKB:Q14586] synonym: "HZF2" EXACT [UniProtKB:Q14586] synonym: "Zinc finger protein 2" EXACT [UniProtKB:Q14586] xref: EMBL:AAF73867.1 xref: EMBL:AAH36367.1 xref: EMBL:CAA55525.1 xref: UniProtKB:Q14586 xref: UniProtKB:Q8NE41 xref: UniProtKB:Q9NRJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020685 ! ZNF267_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072080 ! ZN267_HUMAN-Phosphothreonine424 relationship: transforms_into CCO:B0072081 ! ZN267_HUMAN-Phosphotyrosine520 [Term] id: CCO:B0055999 name: ZN268_HUMAN def: "Zinc finger protein 268" [UniProtKB:Q14587] synonym: "HZF3" EXACT [UniProtKB:Q14587] synonym: "Zinc finger protein 3" EXACT [UniProtKB:Q14587] xref: EMBL:AAG59817.1 xref: EMBL:AAK69307.1 xref: EMBL:CAA55526.1 xref: UniProtKB:Q14587 xref: UniProtKB:Q96RH4 xref: UniProtKB:Q9BZJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020686 ! ZNF268_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056000 name: ZN234_HUMAN def: "Zinc finger protein 234" [UniProtKB:Q14588] synonym: "HZF4" EXACT [UniProtKB:Q14588] synonym: "Zinc finger protein 4" EXACT [UniProtKB:Q14588] xref: EMBL:AAF34785.1 xref: EMBL:AAF88104.1 xref: EMBL:AAH07303.1 xref: EMBL:CAA55527.1 xref: UniProtKB:Q14588 xref: UniProtKB:Q96IR4 xref: UniProtKB:Q9NS45 xref: UniProtKB:Q9NYT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020672 ! ZNF234_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056001 name: ZN235_HUMAN def: "Zinc finger protein 235" [UniProtKB:Q14590] synonym: "HZF6" EXACT [UniProtKB:Q14590] synonym: "Zfp-93" EXACT [UniProtKB:Q14590] synonym: "Zinc finger protein 6" EXACT [UniProtKB:Q14590] synonym: "Zinc finger protein 93 homolog" EXACT [UniProtKB:Q14590] xref: EMBL:AAD12728.1 xref: EMBL:AAD12729.1 xref: EMBL:AAG23969.1 xref: EMBL:AAI17216.1 xref: EMBL:BAG62069.1 xref: EMBL:CAA55529.1 xref: UniProtKB:B4DTQ7 xref: UniProtKB:O14898 xref: UniProtKB:O14899 xref: UniProtKB:Q14590 xref: UniProtKB:Q17RR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020673 ! ZNF235_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056002 name: ZN271_HUMAN def: "Zinc finger protein 271" [UniProtKB:Q14591] synonym: "CT-ZFP48" EXACT [UniProtKB:Q14591] synonym: "Epstein-Barr virus-induced zinc finger protein" EXACT [UniProtKB:Q14591] synonym: "HZF7" EXACT [UniProtKB:Q14591] synonym: "Zinc finger protein 7" EXACT [UniProtKB:Q14591] synonym: "Zinc finger protein dp" EXACT [UniProtKB:Q14591] synonym: "Zinc finger protein ZNFphex133" EXACT [UniProtKB:Q14591] synonym: "ZNF-dp" EXACT [UniProtKB:Q14591] synonym: "ZNF-EB" EXACT [UniProtKB:Q14591] xref: EMBL:AAD38056.1 xref: EMBL:AAD43569.1 xref: EMBL:AAH04510.2 xref: EMBL:AAH17710.1 xref: EMBL:AAK52068.1 xref: EMBL:CAA55530.1 xref: UniProtKB:Q14591 xref: UniProtKB:Q96T29 xref: UniProtKB:Q9BSX2 xref: UniProtKB:Q9UN33 xref: UniProtKB:Q9Y5B7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020687 ! ZNF271_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056003 name: ZN460_HUMAN def: "Zinc finger protein 460" [UniProtKB:Q14592] synonym: "HZF8" EXACT [UniProtKB:Q14592] synonym: "Zinc finger protein 272" EXACT [UniProtKB:Q14592] synonym: "Zinc finger protein 8" EXACT [UniProtKB:Q14592] xref: EMBL:AAI09020.1 xref: EMBL:AAI18626.1 xref: EMBL:AAR00225.1 xref: EMBL:CAA55531.1 xref: UniProtKB:Q14592 xref: UniProtKB:Q2VPC7 xref: UniProtKB:Q6VSF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020759 ! ZNF460_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072128 ! ZN460_HUMAN-Phosphoserine367 [Term] id: CCO:B0056004 name: IHH_HUMAN def: "Indian hedgehog protein precursor" [UniProtKB:Q14623] synonym: "HHG-2" EXACT [UniProtKB:Q14623] synonym: "IHH" EXACT [UniProtKB:Q14623] xref: EMBL:AAA62178.1 xref: EMBL:AAH34757.2 xref: EMBL:BAA33523.2 xref: UniProtKB:O43322 xref: UniProtKB:Q14623 xref: UniProtKB:Q8N4B9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018243 ! IHH_human relationship: has_function CCO:F0001415 ! patched binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: participates_in CCO:P0001595 ! positive regulation of chondrocyte differentiation relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002409 ! regulation of cell differentiation relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002923 ! positive regulation of epithelial cell proliferation [Term] id: CCO:B0056005 name: Q14632_HUMAN def: "Interleukin-5 receptor type 3" [UniProtKB:Q14632] xref: EMBL:CAA43485.1 xref: UniProtKB:Q14632 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021093 ! HSIL5R3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001261 ! interleukin-5 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000452 ! interleukin-5 receptor complex relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0056006 name: INSL4_HUMAN def: "Early placenta insulin-like peptide precursor" [UniProtKB:Q14641] synonym: "EPIL" EXACT [UniProtKB:Q14641] synonym: "Insulin-like peptide 4" EXACT [UniProtKB:Q14641] synonym: "Placentin" EXACT [UniProtKB:Q14641] xref: EMBL:AAB08516.1 xref: EMBL:AAH26254.1 xref: EMBL:CAH70506.1 xref: UniProtKB:Q14641 xref: UniProtKB:Q5W127 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018291 ! INSL4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0056007 name: ITPR1_HUMAN def: "Inositol 1,4,5-trisphosphate receptor type 1" [UniProtKB:Q14643] synonym: "InsP3R1" EXACT [UniProtKB:Q14643] synonym: "IP3 receptor isoform 1" EXACT [UniProtKB:Q14643] synonym: "IP3R" EXACT [UniProtKB:Q14643] synonym: "Type 1 inositol 1,4,5-trisphosphate receptor" EXACT [UniProtKB:Q14643] synonym: "Type 1 InsP3 receptor" EXACT [UniProtKB:Q14643] xref: EMBL:AAB04947.2 xref: EMBL:AAD14386.1 xref: EMBL:BAA05065.1 xref: UniProtKB:Q14643 xref: UniProtKB:Q14660 xref: UniProtKB:Q99897 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018349 ! ITPR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015935 ! itpr1-txndc4-2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067165 ! ITPR1_HUMAN-Phosphotyrosine482 relationship: transforms_into CCO:B0067166 ! ITPR1_HUMAN-Phosphoserine1598 relationship: transforms_into CCO:B0067167 ! ITPR1_HUMAN-Phosphoserine1764 relationship: transforms_into CCO:B0067168 ! ITPR1_HUMAN-Phosphotyrosine2664 [Term] id: CCO:B0056008 name: RASA3_HUMAN def: "Ras GTPase-activating protein 3" [UniProtKB:Q14644] synonym: "GAP1(IP4BP)" EXACT [UniProtKB:Q14644] synonym: "Ins P4-binding protein" EXACT [UniProtKB:Q14644] xref: EMBL:AAH38456.1 xref: EMBL:AAH47242.1 xref: EMBL:BAF82435.1 xref: EMBL:CAA61580.1 xref: EMBL:CAI12864.2 xref: EMBL:CAM28365.1 xref: UniProtKB:A6NL15 xref: UniProtKB:Q14644 xref: UniProtKB:Q8IUY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019623 ! RASA3_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0069744 ! RASA3_HUMAN-Phosphotyrosine66 relationship: transforms_into CCO:B0069745 ! RASA3_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0069746 ! RASA3_HUMAN-Phosphothreonine110 relationship: transforms_into CCO:B0069747 ! RASA3_HUMAN-Phosphotyrosine765 relationship: transforms_into CCO:B0069748 ! RASA3_HUMAN-Phosphoserine809 [Term] id: CCO:B0056009 name: IRF3_HUMAN def: "Interferon regulatory factor 3" [UniProtKB:Q14653] synonym: "IRF-3" EXACT [UniProtKB:Q14653] xref: EMBL:AAC68818.1 xref: EMBL:AAH71721.1 xref: EMBL:CAA91227.1 xref: UniProtKB:Q14653 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018313 ! IRF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0056010 name: Q14663_HUMAN def: "H-2K binding factor-2" [UniProtKB:Q14663] xref: EMBL:AAA91836.1 xref: EMBL:BAA21773.1 xref: UniProtKB:Q14663 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021094 ! KBF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056011 name: PSF1_HUMAN def: "DNA replication complex GINS protein PSF1" [UniProtKB:Q14691] synonym: "GINS complex subunit 1" EXACT [UniProtKB:Q14691] xref: EMBL:AAH12542.1 xref: EMBL:BAA11503.2 xref: EMBL:CAI13764.1 xref: EMBL:CAI43019.1 xref: UniProtKB:Q14691 xref: UniProtKB:Q9NQE2 xref: UniProtKB:Q9NQI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019528 ! GINS1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000477 ! inner cell mass cell proliferation relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0056012 name: HLX_HUMAN def: "H2.0-like homeobox protein" [UniProtKB:Q14774] synonym: "Homeobox protein HB24" EXACT [UniProtKB:Q14774] synonym: "Homeobox protein HLX1" EXACT [UniProtKB:Q14774] xref: EMBL:AAC51346.1 xref: EMBL:AAD13883.1 xref: EMBL:AAF65541.1 xref: EMBL:AAH07294.1 xref: EMBL:AAH33808.1 xref: EMBL:BAD92049.1 xref: EMBL:CAH72120.1 xref: EMBL:EAW93289.1 xref: UniProtKB:Q14774 xref: UniProtKB:Q15988 xref: UniProtKB:Q59HE7 xref: UniProtKB:Q9NZ75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018137 ! HLX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056013 name: CBX2_HUMAN def: "Chromobox protein homolog 2" [UniProtKB:Q14781] xref: EMBL:AAH04252.1 xref: EMBL:CAA54839.1 xref: UniProtKB:Q14781 xref: UniProtKB:Q9BTB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017248 ! CBX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015215 ! cbx2-krtap4_12 physical interaction relationship: participates_in CCO:I0015541 ! cbx2-mdfi physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0056014 name: CASP8_HUMAN def: "Caspase-8 precursor" [UniProtKB:Q14790] synonym: "Apoptotic cysteine protease" EXACT [UniProtKB:Q14790] synonym: "Apoptotic protease Mch-5" EXACT [UniProtKB:Q14790] synonym: "CAP4" EXACT [UniProtKB:Q14790] synonym: "CASP-8" EXACT [UniProtKB:Q14790] synonym: "EC 3.4.22.61" EXACT [UniProtKB:Q14790] synonym: "FADD-homologous ICE/CED-3-like protease" EXACT [UniProtKB:Q14790] synonym: "FADD-like ICE" EXACT [UniProtKB:Q14790] synonym: "FLICE" EXACT [UniProtKB:Q14790] synonym: "ICE-like apoptotic protease 5" EXACT [UniProtKB:Q14790] synonym: "MACH" EXACT [UniProtKB:Q14790] synonym: "MORT1-associated CED-3 homolog" EXACT [UniProtKB:Q14790] xref: EMBL:AAB70913.1 xref: EMBL:AAC50602.1 xref: EMBL:AAC50645.1 xref: EMBL:AAD24962.1 xref: EMBL:AAK57437.1 xref: EMBL:AAL87628.1 xref: EMBL:AAL87629.1 xref: EMBL:AAL87630.1 xref: EMBL:AAL87631.1 xref: EMBL:AAL87632.1 xref: EMBL:AAY24225.1 xref: EMBL:ABC67468.1 xref: EMBL:BAB32555.1 xref: EMBL:CAA66853.1 xref: EMBL:CAA66854.1 xref: EMBL:CAA66855.1 xref: EMBL:CAA66856.1 xref: EMBL:CAA66857.1 xref: EMBL:CAA66858.1 xref: EMBL:CAA66859.1 xref: UniProtKB:O14676 xref: UniProtKB:Q14790 xref: UniProtKB:Q14791 xref: UniProtKB:Q14792 xref: UniProtKB:Q14793 xref: UniProtKB:Q14794 xref: UniProtKB:Q14795 xref: UniProtKB:Q14796 xref: UniProtKB:Q15780 xref: UniProtKB:Q15806 xref: UniProtKB:Q53TT5 xref: UniProtKB:Q8TDI1 xref: UniProtKB:Q8TDI2 xref: UniProtKB:Q8TDI3 xref: UniProtKB:Q8TDI4 xref: UniProtKB:Q8TDI5 xref: UniProtKB:Q96T22 xref: UniProtKB:Q9C0K4 xref: UniProtKB:Q9UQ81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017239 ! CASP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015922 ! tnfsf10-tnfrs10b-1 physical interaction relationship: participates_in CCO:I0016252 ! tradd-traf2-1 physical interaction relationship: participates_in CCO:I0016253 ! tradd-traf2-2 physical interaction relationship: participates_in CCO:I0016254 ! tnfsf6-tnfrsf6-2 physical interaction relationship: participates_in CCO:I0017358 ! fadd-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0017360 ! tnfsf10-tnfrs10a-1 physical interaction relationship: participates_in CCO:I0017361 ! tnfsf10-tnfrs10a-3 physical interaction relationship: participates_in CCO:I0017362 ! tnfsf10-tnfrs10b-4 physical interaction relationship: participates_in CCO:I0017498 ! tnfsf10-tnfrs10a-2 physical interaction relationship: participates_in CCO:I0017674 ! casp8-casp8-1 direct interaction relationship: participates_in CCO:I0017676 ! casp8-caspa-1 direct interaction relationship: participates_in CCO:I0017867 ! tnfsf6-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0018012 ! casp8-casp10-1 physical interaction relationship: participates_in CCO:I0018206 ! casp8-bcap31 physical interaction relationship: participates_in CCO:I0018609 ! tnfsf10-casp10-1 physical interaction relationship: participates_in CCO:I0018610 ! tnfsf6-casp10-2 physical interaction relationship: participates_in CCO:I0018613 ! casp8-ripk1-1 physical interaction relationship: participates_in CCO:I0019491 ! tnfsf10-casp10-2 physical interaction relationship: participates_in CCO:I0019492 ! tnfsf6-casp10-1 physical interaction relationship: participates_in CCO:I0019681 ! casp8-vim physical interaction relationship: participates_in CCO:I0019938 ! casp8-casp8 physical interaction relationship: participates_in CCO:I0019939 ! casp8-chd3 physical interaction relationship: participates_in CCO:I0020189 ! tfcp2-casp8 physical interaction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0000840 ! activation of pro-apoptotic gene products relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0064077 ! CASP8_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0064078 ! CASP8_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0064079 ! CASP8_HUMAN-Phosphotyrosine334 [Term] id: CCO:B0056015 name: ZN846_HUMAN def: "Zinc finger protein 846" [UniProtKB:Q147U1] xref: EMBL:AAI18658.1 xref: EMBL:BAF82225.1 xref: UniProtKB:A8K0H1 xref: UniProtKB:Q147U1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022823 ! ZNF846_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072255 ! ZN846_HUMAN-Phosphoserine98 [Term] id: CCO:B0056016 name: Q14803_HUMAN def: "cDNA FLJ76576, highly similar to Homo sapiens MYC associated factor X (MAX), transcript variant 5, mRNA" [UniProtKB:Q14803] synonym: "Max protein" EXACT [UniProtKB:Q14803] synonym: "MYC associated factor X, isoform CRA_b" EXACT [UniProtKB:Q14803] xref: EMBL:BAF85319.1 xref: EMBL:CAA47339.1 xref: EMBL:EAW80899.1 xref: UniProtKB:Q14803 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021095 ! max_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056017 name: MEF2D_HUMAN def: "Myocyte-specific enhancer factor 2D" [UniProtKB:Q14814] xref: EMBL:AAA59579.1 xref: EMBL:AAA93194.1 xref: EMBL:AAH40949.1 xref: EMBL:AAH54520.1 xref: UniProtKB:Q14814 xref: UniProtKB:Q14815 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018602 ! MEF2D_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068138 ! MEF2D_HUMAN-Phosphoserine98 relationship: transforms_into CCO:B0068139 ! MEF2D_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0068140 ! MEF2D_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0068141 ! MEF2D_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0068142 ! MEF2D_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0068143 ! MEF2D_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0068144 ! MEF2D_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0068145 ! MEF2D_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0068146 ! MEF2D_HUMAN-N6-acetyllysine439 relationship: transforms_into CCO:B0068147 ! MEF2D_HUMAN-Phosphoserine444 [Term] id: CCO:B0056018 name: CHD4_HUMAN def: "Chromodomain-helicase-DNA-binding protein 4" [UniProtKB:Q14839] synonym: "ATP-dependent helicase CHD4" EXACT [UniProtKB:Q14839] synonym: "CHD-4" EXACT [UniProtKB:Q14839] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q14839] synonym: "Mi-2 autoantigen 218 kDa protein" EXACT [UniProtKB:Q14839] synonym: "Mi2-beta" EXACT [UniProtKB:Q14839] xref: EMBL:AAH38596.1 xref: EMBL:CAA60384.1 xref: UniProtKB:Q14839 xref: UniProtKB:Q8IXZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017349 ! CHD4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0064306 ! CHD4_HUMAN-Phosphoserine103 relationship: transforms_into CCO:B0064307 ! CHD4_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0064308 ! CHD4_HUMAN-Phosphoserine515 relationship: transforms_into CCO:B0064309 ! CHD4_HUMAN-Phosphothreonine517 relationship: transforms_into CCO:B0064310 ! CHD4_HUMAN-Phosphothreonine529 relationship: transforms_into CCO:B0064311 ! CHD4_HUMAN-Phosphoserine531 relationship: transforms_into CCO:B0064312 ! CHD4_HUMAN-Phosphoserine1308 relationship: transforms_into CCO:B0064313 ! CHD4_HUMAN-Phosphoserine1349 relationship: transforms_into CCO:B0064314 ! CHD4_HUMAN-Phosphoserine1531 relationship: transforms_into CCO:B0064315 ! CHD4_HUMAN-Phosphoserine1535 relationship: transforms_into CCO:B0064316 ! CHD4_HUMAN-Phosphoserine1537 relationship: transforms_into CCO:B0064317 ! CHD4_HUMAN-Phosphothreonine1540 relationship: transforms_into CCO:B0064318 ! CHD4_HUMAN-Phosphothreonine1542 relationship: transforms_into CCO:B0064319 ! CHD4_HUMAN-Phosphothreonine1545 relationship: transforms_into CCO:B0064320 ! CHD4_HUMAN-Phosphothreonine1549 relationship: transforms_into CCO:B0064321 ! CHD4_HUMAN-Phosphoserine1570 relationship: transforms_into CCO:B0064322 ! CHD4_HUMAN-Phosphoserine1576 relationship: transforms_into CCO:B0064323 ! CHD4_HUMAN-Phosphoserine1602 [Term] id: CCO:B0056019 name: PO6F1_HUMAN def: "POU domain, class 6, transcription factor 1" [UniProtKB:Q14863] synonym: "Brain-5" EXACT [UniProtKB:Q14863] synonym: "Brain-specific homeobox/POU domain protein 5" EXACT [UniProtKB:Q14863] synonym: "Brn-5 protein" EXACT [UniProtKB:Q14863] synonym: "mPOU homeobox protein" EXACT [UniProtKB:Q14863] xref: EMBL:AAH74765.3 xref: EMBL:CAA79977.1 xref: EMBL:CAA79978.1 xref: UniProtKB:Q14863 xref: UniProtKB:Q15944 xref: UniProtKB:Q6DK47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019463 ! POU6F1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056020 name: Q14867_HUMAN def: "K222 protein" [UniProtKB:Q14867] xref: EMBL:CAA54772.1 xref: UniProtKB:Q14867 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021096 ! K222_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals [Term] id: CCO:B0056021 name: Q14868_HUMAN def: "Effector cell protease receptor 1" [UniProtKB:Q14868] xref: EMBL:AAA19687.1 xref: UniProtKB:Q14868 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021097 ! EPR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0056022 name: MTF1_HUMAN def: "Metal regulatory transcription factor 1" [UniProtKB:Q14872] synonym: "MRE-binding transcription factor" EXACT [UniProtKB:Q14872] synonym: "Transcription factor MTF-1" EXACT [UniProtKB:Q14872] xref: EMBL:AAH14454.1 xref: EMBL:CAA55363.1 xref: EMBL:CAH70087.1 xref: UniProtKB:Q14872 xref: UniProtKB:Q96CB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018676 ! MTF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015300 ! ap1m1-mtf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0056023 name: MYPC3_HUMAN def: "Myosin-binding protein C, cardiac-type" [UniProtKB:Q14896] synonym: "C-protein, cardiac muscle isoform" EXACT [UniProtKB:Q14896] synonym: "Cardiac MyBP-C" EXACT [UniProtKB:Q14896] xref: EMBL:AAB35662.1 xref: EMBL:AAC04620.1 xref: EMBL:AAR89909.1 xref: EMBL:CAA58882.1 xref: EMBL:CAA71216.1 xref: UniProtKB:Q14896 xref: UniProtKB:Q16410 xref: UniProtKB:Q6R2F7 xref: UniProtKB:Q9UE27 xref: UniProtKB:Q9UM53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018701 ! MYBPC3_human relationship: has_function CCO:F0000200 ! ATPase activator activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_function CCO:F0003516 ! myosin binding relationship: has_function CCO:F0004666 ! titin binding relationship: has_function CCO:F0004935 ! myosin heavy chain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000426 ! striated muscle thick filament relationship: located_in CCO:C0000744 ! C zone relationship: located_in CCO:C0000933 ! sarcomere relationship: located_in CCO:C0001326 ! A band relationship: participates_in CCO:P0001745 ! regulation of muscle filament sliding relationship: transforms_into CCO:B0068400 ! MYPC3_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0068401 ! MYPC3_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0068402 ! MYPC3_HUMAN-Phosphoserine304 [Term] id: CCO:B0056024 name: Q14901_HUMAN def: "Myc protein" [UniProtKB:Q14901] xref: EMBL:AAA59886.1 xref: UniProtKB:Q14901 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005142 ! MYC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056025 name: ZN169_HUMAN def: "Zinc finger protein 169" [UniProtKB:Q14929] xref: EMBL:AAA70188.1 xref: EMBL:AAH47702.1 xref: UniProtKB:Q14929 xref: UniProtKB:Q6PI28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020638 ! ZNF169_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072057 ! ZN169_HUMAN-Phosphoserine145 [Term] id: CCO:B0056026 name: NFAC4_HUMAN def: "Nuclear factor of activated T-cells, cytoplasmic 4" [UniProtKB:Q14934] synonym: "NF-AT3" EXACT [UniProtKB:Q14934] synonym: "NF-ATc4" EXACT [UniProtKB:Q14934] synonym: "NFATc4" EXACT [UniProtKB:Q14934] synonym: "T-cell transcription factor NFAT3" EXACT [UniProtKB:Q14934] xref: EMBL:AAA79175.1 xref: EMBL:AAH53855.1 xref: EMBL:ACG55661.1 xref: UniProtKB:Q14934 xref: UniProtKB:Q7Z598 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018768 ! NFATC4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068630 ! NFAC4_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0068631 ! NFAC4_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0068632 ! NFAC4_HUMAN-Phosphoserine334 [Term] id: CCO:B0056027 name: GPNMB_HUMAN def: "Transmembrane glycoprotein NMB precursor" [UniProtKB:Q14956] synonym: "Transmembrane glycoprotein HGFIN" EXACT [UniProtKB:Q14956] xref: EMBL:AAG42839.1 xref: EMBL:AAH32783.1 xref: EMBL:AAP22336.1 xref: EMBL:AAQ89481.1 xref: EMBL:CAA54044.1 xref: UniProtKB:Q14956 xref: UniProtKB:Q6UVX1 xref: UniProtKB:Q8N1A1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018001 ! GPNMB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0056028 name: RB39A_HUMAN def: "Ras-related protein Rab-39A" [UniProtKB:Q14964] synonym: "Rab-39" EXACT [UniProtKB:Q14964] xref: EMBL:AAH28064.1 xref: EMBL:CAA68227.1 xref: UniProtKB:Q14964 xref: UniProtKB:Q8N6W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019638 ! RAB39_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069760 ! RB39A_HUMAN-Cysteine methyl ester217 [Term] id: CCO:B0056029 name: Q14968_HUMAN def: "Leukocyte platelet-activating factor receptor" [UniProtKB:Q14968] xref: EMBL:AAB97766.1 xref: UniProtKB:Q14968 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001330 ! platelet activating factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056030 name: NR1I3_HUMAN def: "Nuclear receptor subfamily 1 group I member 3" [UniProtKB:Q14994] synonym: "CAR" EXACT [UniProtKB:Q14994] synonym: "Constitutive activator of retinoid response" EXACT [UniProtKB:Q14994] synonym: "Constitutive active response" EXACT [UniProtKB:Q14994] synonym: "Constitutive androstane receptor" EXACT [UniProtKB:Q14994] synonym: "Orphan nuclear receptor MB67" EXACT [UniProtKB:Q14994] xref: EMBL:AAH69626.1 xref: EMBL:CAA83016.1 xref: UniProtKB:Q14994 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001235 ! androgen receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056031 name: NR1D2_HUMAN def: "Nuclear receptor subfamily 1 group D member 2" [UniProtKB:Q14995] synonym: "EAR-1R" EXACT [UniProtKB:Q14995] synonym: "Orphan nuclear hormone receptor BD73" EXACT [UniProtKB:Q14995] synonym: "Rev-erb-beta" EXACT [UniProtKB:Q14995] xref: EMBL:AAA65937.1 xref: EMBL:AAH45613.1 xref: EMBL:BAA20088.1 xref: UniProtKB:O00402 xref: UniProtKB:Q14995 xref: UniProtKB:Q86XD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018850 ! NR1D2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056032 name: GAPD1_HUMAN def: "GTPase-activating protein and VPS9 domain-containing protein 1" [UniProtKB:Q14C86] synonym: "GAPex-5" EXACT [UniProtKB:Q14C86] synonym: "Rab5-activating protein 6" EXACT [UniProtKB:Q14C86] xref: EMBL:AAH13635.1 xref: EMBL:AAH21119.1 xref: EMBL:AAI14938.1 xref: EMBL:AAI14963.1 xref: EMBL:ABB71126.1 xref: EMBL:BAA90959.1 xref: EMBL:BAA96045.3 xref: EMBL:CAB45770.1 xref: EMBL:CAD38993.1 xref: EMBL:EAW87622.1 xref: EMBL:EAW87623.1 xref: UniProtKB:A8MYK3 xref: UniProtKB:Q14C76 xref: UniProtKB:Q14C86 xref: UniProtKB:Q2Q1W1 xref: UniProtKB:Q8ND92 xref: UniProtKB:Q8WU86 xref: UniProtKB:Q96CZ4 xref: UniProtKB:Q9NXQ1 xref: UniProtKB:Q9P207 xref: UniProtKB:Q9Y4N0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017864 ! GAPVD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0066365 ! GAPD1_HUMAN-Phosphothreonine390 relationship: transforms_into CCO:B0066366 ! GAPD1_HUMAN-Phosphothreonine458 relationship: transforms_into CCO:B0066367 ! GAPD1_HUMAN-Phosphoserine466 relationship: transforms_into CCO:B0066368 ! GAPD1_HUMAN-Phosphothreonine470 relationship: transforms_into CCO:B0066369 ! GAPD1_HUMAN-Phosphoserine566 relationship: transforms_into CCO:B0066370 ! GAPD1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0066371 ! GAPD1_HUMAN-Phosphoserine742 relationship: transforms_into CCO:B0066372 ! GAPD1_HUMAN-Phosphoserine746 relationship: transforms_into CCO:B0066373 ! GAPD1_HUMAN-Phosphothreonine747 relationship: transforms_into CCO:B0066374 ! GAPD1_HUMAN-Phosphoserine748 relationship: transforms_into CCO:B0066375 ! GAPD1_HUMAN-Phosphoserine902 relationship: transforms_into CCO:B0066376 ! GAPD1_HUMAN-Phosphoserine903 relationship: transforms_into CCO:B0066377 ! GAPD1_HUMAN-Phosphoserine966 relationship: transforms_into CCO:B0066378 ! GAPD1_HUMAN-Phosphoserine1019 relationship: transforms_into CCO:B0066379 ! GAPD1_HUMAN-Phosphoserine1096 relationship: transforms_into CCO:B0066380 ! GAPD1_HUMAN-Phosphoserine1105 [Term] id: CCO:B0056033 name: RHG19_HUMAN def: "Rho GTPase-activating protein 19" [UniProtKB:Q14CB8] synonym: "Rho-type GTPase-activating protein 19" EXACT [UniProtKB:Q14CB8] xref: EMBL:AAI13889.1 xref: EMBL:AAI14491.1 xref: EMBL:AAR02412.1 xref: EMBL:ABC69298.1 xref: EMBL:BAB84948.1 xref: EMBL:BAC03428.1 xref: EMBL:BAC04165.1 xref: EMBL:CAH18254.1 xref: EMBL:CAI13728.1 xref: EMBL:CAI13731.2 xref: UniProtKB:A1XCP1 xref: UniProtKB:Q14CB8 xref: UniProtKB:Q14CF2 xref: UniProtKB:Q5J8M2 xref: UniProtKB:Q5T460 xref: UniProtKB:Q5T462 xref: UniProtKB:Q68DG6 xref: UniProtKB:Q8N9X1 xref: UniProtKB:Q8NF34 xref: UniProtKB:Q8TEK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019720 ! ARHGAP19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069955 ! RHG19_HUMAN-Phosphoserine422 [Term] id: CCO:B0056034 name: Q14DU5_HUMAN def: "ROCK2 protein" [UniProtKB:Q14DU5] xref: EMBL:AAI11802.1 xref: UniProtKB:Q14DU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019766 ! ROCK2_human relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056035 name: Q14DW8_HUMAN def: "HOXD11 protein" [UniProtKB:Q14DW8] xref: EMBL:AAI09395.1 xref: UniProtKB:Q14DW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018190 ! HOXD11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056036 name: SUZ12_HUMAN def: "Polycomb protein SUZ12" [UniProtKB:Q15022] synonym: "ChET 9 protein" EXACT [UniProtKB:Q15022] synonym: "Chromatin precipitated E2F target 9 protein" EXACT [UniProtKB:Q15022] synonym: "Joined to JAZF1 protein" EXACT [UniProtKB:Q15022] synonym: "Suppressor of zeste 12 protein homolog" EXACT [UniProtKB:Q15022] xref: EMBL:AAH15704.1 xref: EMBL:BAA09931.1 xref: UniProtKB:Q15022 xref: UniProtKB:Q96BD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020082 ! SUZ12_human relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005616 ! histone methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000182 ! sex chromatin relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001617 ! ESC/E(Z) complex relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0071007 ! SUZ12_HUMAN-Phosphothreonine418 relationship: transforms_into CCO:B0071008 ! SUZ12_HUMAN-Phosphoserine546 relationship: transforms_into CCO:B0071009 ! SUZ12_HUMAN-Phosphoserine583 [Term] id: CCO:B0056037 name: SNX17_HUMAN def: "Sorting nexin-17" [UniProtKB:Q15036] xref: EMBL:AAH02524.1 xref: EMBL:AAH02610.1 xref: EMBL:AAH14620.1 xref: EMBL:AAH50590.1 xref: EMBL:AAP35831.1 xref: EMBL:AAY14844.1 xref: EMBL:BAA06542.2 xref: EMBL:BAD96263.1 xref: EMBL:CAC12897.1 xref: EMBL:CAG33362.1 xref: UniProtKB:Q15036 xref: UniProtKB:Q53HN7 xref: UniProtKB:Q6IAS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019970 ! SNX17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001243 ! regulation of endocytosis relationship: transforms_into CCO:B0070712 ! SNX17_HUMAN-Phosphothreonine334 relationship: transforms_into CCO:B0070713 ! SNX17_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0070714 ! SNX17_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0070715 ! SNX17_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0070716 ! SNX17_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0070717 ! SNX17_HUMAN-Phosphoserine440 [Term] id: CCO:B0056038 name: IQCB1_HUMAN def: "IQ calmodulin-binding motif-containing protein 1" [UniProtKB:Q15051] synonym: "Nephrocystin-5" EXACT [UniProtKB:Q15051] xref: EMBL:AAH05806.1 xref: EMBL:AAW47233.1 xref: EMBL:BAA04968.2 xref: EMBL:BAB93506.1 xref: UniProtKB:Q15051 xref: UniProtKB:Q5DKQ7 xref: UniProtKB:Q8NI79 xref: UniProtKB:Q9BS08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018304 ! IQCB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002849 ! maintenance of organ identity relationship: transforms_into CCO:B0067135 ! IQCB1_HUMAN-Phosphoserine572 [Term] id: CCO:B0056039 name: ARHG6_HUMAN def: "Rho guanine nucleotide exchange factor 6" [UniProtKB:Q15052] synonym: "Alpha-Pix" EXACT [UniProtKB:Q15052] synonym: "COOL-2" EXACT [UniProtKB:Q15052] synonym: "PAK-interacting exchange factor alpha" EXACT [UniProtKB:Q15052] synonym: "Rac/Cdc42 guanine nucleotide exchange factor 6" EXACT [UniProtKB:Q15052] xref: EMBL:AAG27169.1 xref: EMBL:AAH39856.1 xref: EMBL:AAH43505.1 xref: EMBL:BAA02796.1 xref: EMBL:BAA04985.1 xref: EMBL:BAF84431.1 xref: EMBL:CAD97632.1 xref: EMBL:CAI39443.1 xref: EMBL:CAI42899.1 xref: EMBL:EAW88460.1 xref: UniProtKB:A6NMW9 xref: UniProtKB:A8K6S7 xref: UniProtKB:Q15052 xref: UniProtKB:Q15396 xref: UniProtKB:Q5JQ66 xref: UniProtKB:Q7Z3W1 xref: UniProtKB:Q86XH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017016 ! ARHGEF6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0065737 ! ARHG6_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0065738 ! ARHG6_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0065739 ! ARHG6_HUMAN-Phosphoserine488 relationship: transforms_into CCO:B0065740 ! ARHG6_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0065741 ! ARHG6_HUMAN-Phosphothreonine650 relationship: transforms_into CCO:B0065742 ! ARHG6_HUMAN-Phosphoserine684 [Term] id: CCO:B0056040 name: IF4H_HUMAN def: "Eukaryotic translation initiation factor 4H" [UniProtKB:Q15056] synonym: "eIF-4H" EXACT [UniProtKB:Q15056] synonym: "Williams-Beuren syndrome chromosomal region 1 protein" EXACT [UniProtKB:Q15056] xref: EMBL:AAC04859.2 xref: EMBL:AAF75557.1 xref: EMBL:AAH10021.1 xref: EMBL:AAH21214.1 xref: EMBL:AAH66928.1 xref: EMBL:BAA05063.1 xref: UniProtKB:Q15056 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018231 ! EIF4H_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015429 ! bles03-wbscr1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0067045 ! IF4H_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0067046 ! IF4H_HUMAN-Phosphotyrosine12 relationship: transforms_into CCO:B0067047 ! IF4H_HUMAN-Phosphotyrosine45 relationship: transforms_into CCO:B0067048 ! IF4H_HUMAN-Phosphotyrosine101 relationship: transforms_into CCO:B0067049 ! IF4H_HUMAN-Phosphoserine193 [Term] id: CCO:B0056041 name: OZF_HUMAN def: "Zinc finger protein OZF" [UniProtKB:Q15072] synonym: "Only zinc finger protein" EXACT [UniProtKB:Q15072] synonym: "Zinc finger protein 146" EXACT [UniProtKB:Q15072] xref: EMBL:AAI10501.1 xref: EMBL:AAI10502.1 xref: EMBL:CAA49844.1 xref: EMBL:CAB41967.1 xref: UniProtKB:Q15072 xref: UniProtKB:Q2TB94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019257 ! ZNF146_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056042 name: P2RY6_HUMAN def: "P2Y purinoceptor 6" [UniProtKB:Q15077] synonym: "P2Y6" EXACT [UniProtKB:Q15077] xref: EMBL:AAB03572.1 xref: EMBL:AAB80712.1 xref: EMBL:AAB80713.1 xref: EMBL:AAG17247.1 xref: EMBL:AAH00571.1 xref: EMBL:AAH09391.1 xref: EMBL:AAM18129.1 xref: EMBL:AAP35417.1 xref: EMBL:CAA65770.1 xref: UniProtKB:Q15077 xref: UniProtKB:Q15754 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019269 ! P2RY6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_function CCO:F0006064 ! UDP-activated nucleotide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0056043 name: RAGE_HUMAN def: "Advanced glycosylation end product-specific receptor precursor" [UniProtKB:Q15109] synonym: "Receptor for advanced glycosylation end products" EXACT [UniProtKB:Q15109] xref: EMBL:AAA03574.1 xref: EMBL:AAB47491.1 xref: EMBL:AAG35728.1 xref: EMBL:AAH20669.1 xref: EMBL:BAA05958.1 xref: EMBL:BAA89369.1 xref: EMBL:CAB43108.1 xref: EMBL:CAI17535.1 xref: EMBL:CAI17536.1 xref: EMBL:CAI18354.1 xref: EMBL:CAI18355.1 xref: EMBL:CAI41809.1 xref: EMBL:CAI41810.1 xref: UniProtKB:Q15109 xref: UniProtKB:Q15279 xref: UniProtKB:Q9H2X7 xref: UniProtKB:Q9Y3R3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019615 ! AGER_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0056044 name: PLCL1_HUMAN def: "Inactive phospholipase C-like protein 1" [UniProtKB:Q15111] synonym: "Phospholipase C-deleted in lung carcinoma" EXACT [UniProtKB:Q15111] synonym: "Phospholipase C-related but catalytically inactive protein" EXACT [UniProtKB:Q15111] synonym: "PLC-L1" EXACT [UniProtKB:Q15111] synonym: "PRIP" EXACT [UniProtKB:Q15111] xref: EMBL:AAI01532.1 xref: EMBL:AAI11986.1 xref: EMBL:AAY14733.1 xref: EMBL:BAA07688.1 xref: EMBL:CAD97684.1 xref: UniProtKB:Q15111 xref: UniProtKB:Q3MJ90 xref: UniProtKB:Q53SD3 xref: UniProtKB:Q7Z3S3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019437 ! PLCL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069400 ! PLCL1_HUMAN-Phosphothreonine93 relationship: transforms_into CCO:B0069401 ! PLCL1_HUMAN-Phosphoserine95 [Term] id: CCO:B0056045 name: PEA15_HUMAN def: "Astrocytic phosphoprotein PEA-15" [UniProtKB:Q15121] synonym: "PED" EXACT [UniProtKB:Q15121] synonym: "Phosphoprotein enriched in diabetes" EXACT [UniProtKB:Q15121] xref: EMBL:AAD56775.1 xref: EMBL:AAH02426.1 xref: EMBL:AAH22554.1 xref: EMBL:AAP35916.1 xref: EMBL:CAA60499.1 xref: EMBL:CAA74076.1 xref: UniProtKB:O00511 xref: UniProtKB:Q15121 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019358 ! PEA15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019889 ! abcd4-pea15 physical interaction relationship: participates_in CCO:I0020356 ! l1cam-pea15 physical interaction relationship: participates_in CCO:I0020359 ! luc7l2-pea15 physical interaction relationship: participates_in CCO:I0020617 ! pank4-pea15 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0069197 ! PEA15_HUMAN-Phosphothreonine6 relationship: transforms_into CCO:B0069198 ! PEA15_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0069199 ! PEA15_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0069200 ! PEA15_HUMAN-Phosphotyrosine108 relationship: transforms_into CCO:B0069201 ! PEA15_HUMAN-Phosphoserine116 [Term] id: CCO:B0056046 name: Q15142_HUMAN def: "Polycystic kidney disease-associated protein" [UniProtKB:Q15142] xref: EMBL:AAB59488.1 xref: UniProtKB:Q15142 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019409 ! PKD1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056047 name: PLCB4_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4" [UniProtKB:Q15147] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q15147] synonym: "Phosphoinositide phospholipase C" EXACT [UniProtKB:Q15147] synonym: "Phospholipase C-beta-4" EXACT [UniProtKB:Q15147] synonym: "PLC-beta-4" EXACT [UniProtKB:Q15147] xref: EMBL:AAB02027.1 xref: EMBL:AAI17459.1 xref: EMBL:CAI42213.1 xref: EMBL:CAI43087.1 xref: UniProtKB:Q15147 xref: UniProtKB:Q17R56 xref: UniProtKB:Q5JYS8 xref: UniProtKB:Q5JYT0 xref: UniProtKB:Q5JYT4 xref: UniProtKB:Q9BQW5 xref: UniProtKB:Q9BQW6 xref: UniProtKB:Q9BQW8 xref: UniProtKB:Q9UJQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019429 ! PLCB4_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019315 ! nmdar1-plcb4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069389 ! PLCB4_HUMAN-Phosphoserine620 relationship: transforms_into CCO:B0069390 ! PLCB4_HUMAN-Phosphotyrosine623 relationship: transforms_into CCO:B0069391 ! PLCB4_HUMAN-Phosphoserine890 [Term] id: CCO:B0056048 name: TCAL1_HUMAN def: "Transcription elongation factor A protein-like 1" [UniProtKB:Q15170] synonym: "Nuclear phosphoprotein p21/SIIR" EXACT [UniProtKB:Q15170] synonym: "TCEA-like protein 1" EXACT [UniProtKB:Q15170] synonym: "Transcription elongation factor S-II protein-like 1" EXACT [UniProtKB:Q15170] xref: EMBL:AAA60149.1 xref: EMBL:AAD17840.1 xref: EMBL:AAH00809.1 xref: EMBL:CAB55700.1 xref: UniProtKB:Q15170 xref: UniProtKB:Q9UJQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020200 ! TCEAL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071244 ! TCAL1_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0071245 ! TCAL1_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0071246 ! TCAL1_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0071247 ! TCAL1_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0071248 ! TCAL1_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0071249 ! TCAL1_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0071250 ! TCAL1_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0071251 ! TCAL1_HUMAN-Phosphoserine48 [Term] id: CCO:B0056049 name: TEBP_HUMAN def: "Prostaglandin E synthase 3" [UniProtKB:Q15185] synonym: "cPGES" EXACT [UniProtKB:Q15185] synonym: "Cytosolic prostaglandin E2 synthase" EXACT [UniProtKB:Q15185] synonym: "EC 5.3.99.3" EXACT [UniProtKB:Q15185] synonym: "Hsp90 co-chaperone" EXACT [UniProtKB:Q15185] synonym: "Progesterone receptor complex p23" EXACT [UniProtKB:Q15185] synonym: "Telomerase-binding protein p23" EXACT [UniProtKB:Q15185] xref: EMBL:AAA18537.1 xref: EMBL:AAH03005.1 xref: EMBL:AAH21167.1 xref: UniProtKB:Q15185 xref: UniProtKB:Q8WU70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020226 ! PTGES3_human relationship: has_function CCO:F0000306 ! telomerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0007573 ! prostaglandin-E synthase activity relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000297 ! telomerase holoenzyme complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071317 ! TEBP_HUMAN-N6-acetyllysine33 relationship: transforms_into CCO:B0071318 ! TEBP_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0071319 ! TEBP_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0071320 ! TEBP_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0071321 ! TEBP_HUMAN-Phosphoserine151 [Term] id: CCO:B0056050 name: PWP2_HUMAN def: "Periodic tryptophan protein 2 homolog" [UniProtKB:Q15269] xref: EMBL:AAB08084.1 xref: EMBL:AAC50904.1 xref: EMBL:AAC50905.1 xref: EMBL:AAH13309.1 xref: EMBL:AAH14988.1 xref: EMBL:BAA21100.1 xref: EMBL:BAA21137.1 xref: EMBL:BAA95553.1 xref: EMBL:CAA64560.1 xref: EMBL:CAA65284.1 xref: EMBL:CAA65285.1 xref: UniProtKB:Q15269 xref: UniProtKB:Q96A77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019561 ! PWP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020416 ! pwp2h-tom1l1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069641 ! PWP2_HUMAN-Phosphothreonine746 relationship: transforms_into CCO:B0069642 ! PWP2_HUMAN-Phosphoserine891 relationship: transforms_into CCO:B0069643 ! PWP2_HUMAN-Phosphoserine898 relationship: transforms_into CCO:B0069644 ! PWP2_HUMAN-Phosphoserine902 relationship: transforms_into CCO:B0069645 ! PWP2_HUMAN-Phosphoserine913 [Term] id: CCO:B0056051 name: NKX11_HUMAN def: "NK1 transcription factor-related protein 1" [UniProtKB:Q15270] synonym: "Homeobox protein 153" EXACT [UniProtKB:Q15270] synonym: "Homeobox protein SAX-2" EXACT [UniProtKB:Q15270] synonym: "HPX-153" EXACT [UniProtKB:Q15270] synonym: "NKX-1.1" EXACT [UniProtKB:Q15270] xref: EMBL:CAA54282.1 xref: UniProtKB:Q15270 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018792 ! NKX1-1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056052 name: RASA2_HUMAN def: "Ras GTPase-activating protein 2" [UniProtKB:Q15283] synonym: "GAP1m" EXACT [UniProtKB:Q15283] xref: EMBL:AAD09821.1 xref: EMBL:BAA11230.1 xref: EMBL:BAA11231.1 xref: EMBL:BAA11621.1 xref: EMBL:BAA11622.1 xref: UniProtKB:O00695 xref: UniProtKB:Q15283 xref: UniProtKB:Q15284 xref: UniProtKB:Q92594 xref: UniProtKB:Q99577 xref: UniProtKB:Q9UEQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019622 ! RASA2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0056053 name: Q15285_HUMAN def: "C-ras-Ki-2 activated oncogene" [UniProtKB:Q15285] xref: EMBL:AAA36555.1 xref: UniProtKB:Q15285 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056054 name: RAB35_HUMAN def: "Ras-related protein Rab-35" [UniProtKB:Q15286] synonym: "GTP-binding protein RAY" EXACT [UniProtKB:Q15286] synonym: "Rab-1C" EXACT [UniProtKB:Q15286] xref: EMBL:AAC83182.1 xref: EMBL:AAH15931.1 xref: EMBL:AAM21108.1 xref: EMBL:AAV38827.1 xref: EMBL:CAA56177.1 xref: EMBL:CAG38725.1 xref: EMBL:CAG46484.1 xref: UniProtKB:Q15286 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019590 ! RAB35_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001669 ! phosphatidylinositol-4,5-bisphosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001173 ! cell projection membrane relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0001894 ! intercellular bridge relationship: located_in CCO:C0001949 ! clathrin-coated endocytic vesicle relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0020427 ! rab35-cbr3 physical interaction relationship: participates_in CCO:I0020428 ! rab35-tbpl1 physical interaction relationship: participates_in CCO:I0020641 ! rab35-flj21945 physical interaction relationship: participates_in CCO:I0020642 ! rab35-gnpat physical interaction relationship: participates_in CCO:I0020643 ! rab35-idh3b physical interaction relationship: participates_in CCO:I0020644 ! rab35-ptprs physical interaction relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056055 name: Q15299_HUMAN def: "RARB protein" [UniProtKB:Q15299] xref: EMBL:AAA60264.1 xref: UniProtKB:Q15299 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008057 ! RARB_human relationship: has_function CCO:F0000296 ! retinoic acid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056056 name: IRF4_HUMAN def: "Interferon regulatory factor 4" [UniProtKB:Q15306] synonym: "IRF-4" EXACT [UniProtKB:Q15306] synonym: "LSIRF" EXACT [UniProtKB:Q15306] synonym: "Lymphocyte-specific interferon regulatory factor" EXACT [UniProtKB:Q15306] synonym: "Multiple myeloma oncogene 1" EXACT [UniProtKB:Q15306] synonym: "NF-EM5" EXACT [UniProtKB:Q15306] xref: EMBL:AAB37258.1 xref: EMBL:AAC50779.1 xref: EMBL:AAH15752.1 xref: EMBL:CAH71554.1 xref: EMBL:CAH72537.1 xref: UniProtKB:Q15306 xref: UniProtKB:Q5VUI7 xref: UniProtKB:Q99660 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018314 ! IRF4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015711 ! irf4-traf2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002274 ! positive regulation of interleukin-10 biosynthetic process relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002309 ! positive regulation of interleukin-13 biosynthetic process relationship: participates_in CCO:P0002345 ! positive regulation of interleukin-4 biosynthetic process relationship: participates_in CCO:P0002436 ! regulation of T-helper cell differentiation relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0056057 name: RBP1_HUMAN def: "RalA-binding protein 1" [UniProtKB:Q15311] synonym: "76 kDa Ral-interacting protein" EXACT [UniProtKB:Q15311] synonym: "Dinitrophenyl S-glutathione ATPase" EXACT [UniProtKB:Q15311] synonym: "DNP-SG ATPase" EXACT [UniProtKB:Q15311] synonym: "Ral-interacting protein 1" EXACT [UniProtKB:Q15311] synonym: "RalBP1" EXACT [UniProtKB:Q15311] xref: EMBL:AAB00103.1 xref: EMBL:AAH13126.1 xref: UniProtKB:Q15311 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019649 ! RALBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015479 ! hook2-ralbp1 physical interaction relationship: participates_in CCO:I0015824 ! ralb-ralbp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0002157 ! positive regulation of Cdc42 GTPase activity relationship: transforms_into CCO:B0069826 ! RBP1_HUMAN-Phosphothreonine27 relationship: transforms_into CCO:B0069827 ! RBP1_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0069828 ! RBP1_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0069829 ! RBP1_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0069830 ! RBP1_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0069831 ! RBP1_HUMAN-Phosphoserine93 [Term] id: CCO:B0056058 name: ANKR1_HUMAN def: "Ankyrin repeat domain-containing protein 1" [UniProtKB:Q15327] synonym: "C-193" EXACT [UniProtKB:Q15327] synonym: "Cardiac ankyrin repeat protein" EXACT [UniProtKB:Q15327] synonym: "Cytokine-inducible nuclear protein" EXACT [UniProtKB:Q15327] xref: EMBL:AAH18667.1 xref: EMBL:AAX23581.1 xref: EMBL:CAA58676.1 xref: EMBL:CAC70101.1 xref: UniProtKB:Q15327 xref: UniProtKB:Q96LE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016975 ! ANKRD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001328 ! I band relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056059 name: ANGP1_HUMAN def: "Angiopoietin-1 precursor" [UniProtKB:Q15389] synonym: "ANG-1" EXACT [UniProtKB:Q15389] xref: EMBL:AAB50557.1 xref: EMBL:AAM81745.1 xref: EMBL:AAM92271.1 xref: EMBL:BAA02793.2 xref: EMBL:BAB91325.1 xref: UniProtKB:Q15389 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016972 ! ANGPT1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056060 name: P2Y14_HUMAN def: "P2Y purinoceptor 14" [UniProtKB:Q15391] synonym: "G-protein coupled receptor 105" EXACT [UniProtKB:Q15391] synonym: "P2Y14" EXACT [UniProtKB:Q15391] synonym: "UDP-glucose receptor" EXACT [UniProtKB:Q15391] xref: EMBL:AAH34989.1 xref: EMBL:AAL47764.1 xref: EMBL:BAA02791.2 xref: UniProtKB:Q15391 xref: UniProtKB:Q8IYT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019274 ! P2RY14_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_function CCO:F0006064 ! UDP-activated nucleotide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056061 name: RSU1_HUMAN def: "Ras suppressor protein 1" [UniProtKB:Q15404] synonym: "RSP-1" EXACT [UniProtKB:Q15404] synonym: "Rsu-1" EXACT [UniProtKB:Q15404] xref: EMBL:AAA60292.1 xref: EMBL:AAH05993.1 xref: EMBL:AAH08691.1 xref: EMBL:AAH15644.1 xref: UniProtKB:Q15404 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019807 ! RSU1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056062 name: SAFB1_HUMAN def: "Scaffold attachment factor B1" [UniProtKB:Q15424] synonym: "HSP27 ERE-TATA-binding protein" EXACT [UniProtKB:Q15424] synonym: "HSP27 estrogen response element-TATA box-binding protein" EXACT [UniProtKB:Q15424] synonym: "SAB-B1" EXACT [UniProtKB:Q15424] synonym: "SAF-B" EXACT [UniProtKB:Q15424] xref: EMBL:AAC00056.1 xref: EMBL:AAC14667.1 xref: EMBL:AAC18697.1 xref: EMBL:BAD92017.1 xref: UniProtKB:O60406 xref: UniProtKB:Q15424 xref: UniProtKB:Q59HH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019830 ! SAFB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018454 ! bat5-safb physical interaction relationship: participates_in CCO:I0019819 ! safb-chd3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070291 ! SAFB1_HUMAN-Phosphoserine55 relationship: transforms_into CCO:B0070292 ! SAFB1_HUMAN-Phosphoserine288 relationship: transforms_into CCO:B0070293 ! SAFB1_HUMAN-Phosphoserine344 relationship: transforms_into CCO:B0070294 ! SAFB1_HUMAN-Phosphoserine373 relationship: transforms_into CCO:B0070295 ! SAFB1_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0070296 ! SAFB1_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0070297 ! SAFB1_HUMAN-Phosphoserine555 relationship: transforms_into CCO:B0070298 ! SAFB1_HUMAN-Phosphoserine557 relationship: transforms_into CCO:B0070299 ! SAFB1_HUMAN-Phosphoserine589 relationship: transforms_into CCO:B0070300 ! SAFB1_HUMAN-Phosphoserine601 relationship: transforms_into CCO:B0070301 ! SAFB1_HUMAN-Phosphoserine604 relationship: transforms_into CCO:B0070302 ! SAFB1_HUMAN-Phosphoserine808 [Term] id: CCO:B0056063 name: CYH1_HUMAN def: "Cytohesin-1" [UniProtKB:Q15438] synonym: "PH, SEC7 and coiled-coil domain-containing protein 1" EXACT [UniProtKB:Q15438] synonym: "SEC7 homolog B2-1" EXACT [UniProtKB:Q15438] xref: EMBL:AAA36602.1 xref: EMBL:AAF37737.1 xref: EMBL:AAF37738.1 xref: EMBL:AAH38385.1 xref: EMBL:AAH50452.1 xref: UniProtKB:A6NFW7 xref: UniProtKB:Q15438 xref: UniProtKB:Q9P123 xref: UniProtKB:Q9P124 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017509 ! CYTH1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0015997 ! pscdbp-pscd1-1 physical interaction relationship: participates_in CCO:I0015998 ! pscd1-pscdbp-1 physical interaction relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0056064 name: Q15452_HUMAN def: "Protein-serine/threonine kinase" [UniProtKB:Q15452] xref: EMBL:CAA80917.1 xref: UniProtKB:Q15452 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0056065 name: SHB_HUMAN def: "SH2 domain-containing adapter protein B" [UniProtKB:Q15464] xref: EMBL:AAH94765.1 xref: EMBL:CAA53091.1 xref: EMBL:CAH73120.1 xref: EMBL:CAH73192.1 xref: EMBL:CAI13876.1 xref: UniProtKB:Q15464 xref: UniProtKB:Q504U5 xref: UniProtKB:Q5VUM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019892 ! SHB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070490 ! SHB_HUMAN-Phosphotyrosine114 relationship: transforms_into CCO:B0070491 ! SHB_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0070492 ! SHB_HUMAN-Phosphotyrosine246 relationship: transforms_into CCO:B0070493 ! SHB_HUMAN-Phosphotyrosine268 relationship: transforms_into CCO:B0070494 ! SHB_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0070495 ! SHB_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0070496 ! SHB_HUMAN-Phosphotyrosine336 relationship: transforms_into CCO:B0070497 ! SHB_HUMAN-Phosphoserine388 [Term] id: CCO:B0056066 name: SHH_HUMAN def: "Sonic hedgehog protein precursor" [UniProtKB:Q15465] synonym: "HHG-1" EXACT [UniProtKB:Q15465] synonym: "SHH" EXACT [UniProtKB:Q15465] xref: EMBL:AAA62179.1 xref: EMBL:AAB67604.1 xref: EMBL:AAQ87879.1 xref: EMBL:AAS01990.1 xref: UniProtKB:Q15465 xref: UniProtKB:Q75MC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019896 ! SHH_human relationship: has_function CCO:F0001415 ! patched binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005826 ! laminin-1 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000524 ! positive regulation of neuroblast proliferation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0000761 ! positive regulation of hh target transcription factor activity relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001210 ! smoothened signaling pathway in regulation of granule cell precursor cell proliferation relationship: participates_in CCO:P0001212 ! positive regulation of granule cell precursor proliferation relationship: participates_in CCO:P0001246 ! regulation of proteolysis relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0001342 ! regulation of epithelial cell differentiation relationship: participates_in CCO:P0001616 ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: participates_in CCO:P0002480 ! positive regulation of neuron differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002714 ! negative regulation of alpha-beta T cell differentiation [Term] id: CCO:B0056067 name: NR0B2_HUMAN def: "Nuclear receptor subfamily 0 group B member 2" [UniProtKB:Q15466] synonym: "Orphan nuclear receptor SHP" EXACT [UniProtKB:Q15466] synonym: "Small heterodimer partner" EXACT [UniProtKB:Q15466] xref: EMBL:AAC41998.1 xref: EMBL:AAH30207.1 xref: EMBL:BAB68530.1 xref: EMBL:CAI13562.1 xref: UniProtKB:Q15466 xref: UniProtKB:Q5QP36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018848 ! NR0B2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056068 name: STIL_HUMAN def: "SCL-interrupting locus protein" [UniProtKB:Q15468] synonym: "TAL-1-interrupting locus protein" EXACT [UniProtKB:Q15468] xref: EMBL:AAA60550.1 xref: EMBL:AAI26224.1 xref: EMBL:AAK51418.1 xref: EMBL:CAH18699.1 xref: EMBL:CAI13468.1 xref: EMBL:CAI19733.1 xref: UniProtKB:Q15468 xref: UniProtKB:Q5T0C5 xref: UniProtKB:Q68CN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020069 ! STIL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0070973 ! STIL_HUMAN-Phosphoserine753 relationship: transforms_into CCO:B0070974 ! STIL_HUMAN-Phosphoserine1004 [Term] id: CCO:B0056069 name: SIX1_HUMAN def: "Homeobox protein SIX1" [UniProtKB:Q15475] synonym: "Sine oculis homeobox homolog 1" EXACT [UniProtKB:Q15475] xref: EMBL:AAH08874.1 xref: EMBL:AAK06772.1 xref: EMBL:CAA62974.1 xref: UniProtKB:Q15475 xref: UniProtKB:Q96H64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019920 ! SIX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:I0015073 ! mdfi-six1 physical interaction relationship: participates_in CCO:I0019430 ! six1-mdf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation [Term] id: CCO:B0056070 name: RGN_HUMAN def: "Regucalcin" [UniProtKB:Q15493] synonym: "RC" EXACT [UniProtKB:Q15493] synonym: "Senescence marker protein 30" EXACT [UniProtKB:Q15493] synonym: "SMP-30" EXACT [UniProtKB:Q15493] xref: EMBL:AAH50371.1 xref: EMBL:AAH73173.1 xref: EMBL:BAA06602.1 xref: EMBL:BAA78693.1 xref: EMBL:BAA84082.1 xref: EMBL:BAD97080.1 xref: EMBL:CAI41697.1 xref: UniProtKB:A4FTW1 xref: UniProtKB:Q15493 xref: UniProtKB:Q53FC9 xref: UniProtKB:Q5JRR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019698 ! RGN_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002966 ! regulation of calcium-mediated signaling relationship: transforms_into CCO:B0069918 ! RGN_HUMAN-Phosphoserine3 [Term] id: CCO:B0056071 name: SP17_HUMAN def: "Sperm surface protein Sp17" [UniProtKB:Q15506] synonym: "Cancer/testis antigen 22" EXACT [UniProtKB:Q15506] synonym: "CT22" EXACT [UniProtKB:Q15506] synonym: "Sp17-1" EXACT [UniProtKB:Q15506] synonym: "Sperm autoantigenic protein 17" EXACT [UniProtKB:Q15506] synonym: "Sperm protein 17" EXACT [UniProtKB:Q15506] xref: EMBL:AAH32457.1 xref: EMBL:AAK20878.1 xref: EMBL:AAK28125.1 xref: EMBL:CAA88459.1 xref: UniProtKB:Q15506 xref: UniProtKB:Q9BXF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019999 ! SPA17_human relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056072 name: TAF11_HUMAN def: "Transcription initiation factor TFIID subunit 11" [UniProtKB:Q15544] synonym: "TAF(II)28" EXACT [UniProtKB:Q15544] synonym: "TAFII-28" EXACT [UniProtKB:Q15544] synonym: "TAFII28" EXACT [UniProtKB:Q15544] synonym: "TFIID subunit p30-beta" EXACT [UniProtKB:Q15544] synonym: "Transcription initiation factor TFIID 28 kDa subunit" EXACT [UniProtKB:Q15544] xref: EMBL:AAF22038.1 xref: EMBL:AAH21972.1 xref: EMBL:AAO25652.1 xref: EMBL:AAV38211.1 xref: EMBL:AAV38212.1 xref: EMBL:BAA23620.1 xref: EMBL:CAA58780.1 xref: EMBL:CAB96725.1 xref: EMBL:CAG46865.1 xref: UniProtKB:Q15544 xref: UniProtKB:Q9UHS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020130 ! TAF11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:I0018112 ! taf11-taf13-3 direct interaction relationship: participates_in CCO:I0018113 ! taf11-taf13-4 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071084 ! TAF11_HUMAN-Phosphoserine60 [Term] id: CCO:B0056073 name: TAF7_HUMAN def: "Transcription initiation factor TFIID subunit 7" [UniProtKB:Q15545] synonym: "RNA polymerase II TBP-associated factor subunit F" EXACT [UniProtKB:Q15545] synonym: "TAF(II)55" EXACT [UniProtKB:Q15545] synonym: "TAFII-55" EXACT [UniProtKB:Q15545] synonym: "TAFII55" EXACT [UniProtKB:Q15545] synonym: "Transcription initiation factor TFIID 55 kDa subunit" EXACT [UniProtKB:Q15545] xref: EMBL:AAB60347.1 xref: EMBL:AAH32737.1 xref: EMBL:AAK30585.1 xref: EMBL:CAA66636.1 xref: UniProtKB:Q13036 xref: UniProtKB:Q15545 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020140 ! TAF7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071106 ! TAF7_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0071107 ! TAF7_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0071108 ! TAF7_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0071109 ! TAF7_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0071110 ! TAF7_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0071111 ! TAF7_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0071112 ! TAF7_HUMAN-Phosphoserine264 [Term] id: CCO:B0056074 name: Q15552_HUMAN def: "CACCC box-binding protein" [UniProtKB:Q15552] xref: EMBL:AAA36664.1 xref: UniProtKB:Q15552 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021099 ! tb protein_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056075 name: TAF1A_HUMAN def: "TATA box-binding protein-associated factor RNA polymerase I subunit A" [UniProtKB:Q15573] synonym: "TAFI48" EXACT [UniProtKB:Q15573] synonym: "TATA box-binding protein-associated factor 1A" EXACT [UniProtKB:Q15573] synonym: "TBP-associated factor 1A" EXACT [UniProtKB:Q15573] synonym: "TBP-associated factor RNA polymerase I 48 kDa" EXACT [UniProtKB:Q15573] synonym: "Transcription factor SL1" EXACT [UniProtKB:Q15573] xref: EMBL:AAA62862.1 xref: EMBL:AAH13808.1 xref: EMBL:BAA91482.1 xref: EMBL:CAI40466.1 xref: EMBL:CAI40467.1 xref: UniProtKB:Q15573 xref: UniProtKB:Q9NWA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020131 ! TAF1A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000290 ! RNA polymerase I transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000010 ! RNA polymerase I transcription factor complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056076 name: NCOA2_HUMAN def: "Nuclear receptor coactivator 2" [UniProtKB:Q15596] synonym: "NCoA-2" EXACT [UniProtKB:Q15596] synonym: "Transcriptional intermediary factor 2" EXACT [UniProtKB:Q15596] xref: EMBL:CAA66263.1 xref: UniProtKB:Q15596 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018729 ! NCOA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018211 ! ncoa3-crebbp-ncoa2-1 physical interaction relationship: participates_in CCO:I0018213 ! ncoa1-ncoa2-crebbp physical interaction relationship: participates_in CCO:I0018752 ! ar-ncoa2-2 direct interaction relationship: participates_in CCO:I0018753 ! ar-ncoa2-3 direct interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068475 ! NCOA2_HUMAN-Phosphoserine493 relationship: transforms_into CCO:B0068476 ! NCOA2_HUMAN-Phosphoserine699 relationship: transforms_into CCO:B0068477 ! NCOA2_HUMAN-Phosphoserine716 [Term] id: CCO:B0056077 name: DIXC1_HUMAN def: "Dixin" [UniProtKB:Q155Q3] synonym: "Coiled-coil protein DIX1" EXACT [UniProtKB:Q155Q3] synonym: "Coiled-coil-DIX1" EXACT [UniProtKB:Q155Q3] synonym: "DIX domain-containing protein 1" EXACT [UniProtKB:Q155Q3] xref: EMBL:AAH33034.1 xref: EMBL:AAH35509.1 xref: EMBL:AAH41626.2 xref: EMBL:AAH64479.1 xref: EMBL:AAI28601.1 xref: EMBL:ABG25914.1 xref: EMBL:BAB21826.1 xref: EMBL:BAB71039.1 xref: UniProtKB:A1A5D8 xref: UniProtKB:Q155Q3 xref: UniProtKB:Q6P2J8 xref: UniProtKB:Q6PIK4 xref: UniProtKB:Q8IVY4 xref: UniProtKB:Q96N69 xref: UniProtKB:Q9C0C8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017578 ! DIXDC1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0064765 ! DIXC1_HUMAN-Phosphotyrosine642 [Term] id: CCO:B0056078 name: OR1Q1_HUMAN def: "Olfactory receptor 1Q1" [UniProtKB:Q15612] synonym: "Olfactory receptor 9-A" EXACT [UniProtKB:Q15612] synonym: "Olfactory receptor OR9-25" EXACT [UniProtKB:Q15612] synonym: "Olfactory receptor TPCR106" EXACT [UniProtKB:Q15612] synonym: "OR9-A" EXACT [UniProtKB:Q15612] synonym: "OST226" EXACT [UniProtKB:Q15612] xref: EMBL:AAK95046.1 xref: EMBL:BAC05943.1 xref: EMBL:CAA61814.1 xref: EMBL:CAI16288.1 xref: EMBL:DAA04626.1 xref: UniProtKB:Q15612 xref: UniProtKB:Q6IFN4 xref: UniProtKB:Q8NGR7 xref: UniProtKB:Q96R82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019079 ! OR1Q1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056079 name: OR4D1_HUMAN def: "Olfactory receptor 4D1" [UniProtKB:Q15615] synonym: "Olfactory receptor TPCR16" EXACT [UniProtKB:Q15615] xref: EMBL:AAK95052.1 xref: EMBL:BAC06128.1 xref: EMBL:CAA61817.1 xref: UniProtKB:Q15615 xref: UniProtKB:Q8NGB1 xref: UniProtKB:Q96R76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019143 ! OR4D1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056080 name: OR1C1_HUMAN def: "Olfactory receptor 1C1" [UniProtKB:Q15619] synonym: "Olfactory receptor OR1-42" EXACT [UniProtKB:Q15619] synonym: "Olfactory receptor TPCR27" EXACT [UniProtKB:Q15619] xref: EMBL:AAK95045.1 xref: EMBL:BAC05851.1 xref: EMBL:CAA61821.1 xref: EMBL:CAH70622.1 xref: EMBL:DAA04763.1 xref: UniProtKB:Q15619 xref: UniProtKB:Q5VVD2 xref: UniProtKB:Q6IF97 xref: UniProtKB:Q8NGZ1 xref: UniProtKB:Q96R83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019060 ! OR1C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0068981 ! OR1C1_HUMAN-Phosphothreonine7 [Term] id: CCO:B0056081 name: OR8B8_HUMAN def: "Olfactory receptor 8B8" [UniProtKB:Q15620] synonym: "Olfactory receptor TPCR85" EXACT [UniProtKB:Q15620] synonym: "Olfactory-like receptor JCG8" EXACT [UniProtKB:Q15620] xref: EMBL:AAK94995.1 xref: EMBL:AAL32997.1 xref: EMBL:BAC06051.1 xref: EMBL:CAA61822.1 xref: UniProtKB:Q15620 xref: UniProtKB:Q96RC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019225 ! OR8B8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056082 name: OR7A5_HUMAN def: "Olfactory receptor 7A5" [UniProtKB:Q15622] synonym: "Olfactory receptor OR19-17" EXACT [UniProtKB:Q15622] synonym: "Olfactory receptor TPCR92" EXACT [UniProtKB:Q15622] xref: EMBL:AAC25626.1 xref: EMBL:AAI04810.1 xref: EMBL:AAK95028.1 xref: EMBL:CAA61824.1 xref: EMBL:CAA71558.1 xref: EMBL:DAA04619.1 xref: UniProtKB:Q15622 xref: UniProtKB:Q6IFP1 xref: UniProtKB:Q96R96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019214 ! OR7A5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056083 name: Q15625_HUMAN def: "Steroid receptor (TR2-11)" [UniProtKB:Q15625] xref: EMBL:AAA36761.1 xref: UniProtKB:Q15625 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056084 name: Q15626_HUMAN def: "Nuclear receptor subfamily 2, group C, member 1" [UniProtKB:Q15626] synonym: "Nuclear receptor subfamily 2, group C, member 1, isoform CRA_b" EXACT [UniProtKB:Q15626] synonym: "Steroid receptor (TR2-9)" EXACT [UniProtKB:Q15626] xref: EMBL:AAA36762.1 xref: EMBL:AAH40141.1 xref: EMBL:EAW97518.1 xref: UniProtKB:Q15626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018856 ! NR2C1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056085 name: Q15627_HUMAN def: "TR3beta (Nuclear receptor subfamily 4, group A, member 1, isoform CRA_c) (cDNA, FLJ95235, Homo sapiens nuclear receptor subfamily 4, group A, member 1(NR4A1), transcript variant 3, mRNA)" [UniProtKB:Q15627] xref: EMBL:BAA12746.1 xref: EMBL:BAG37048.1 xref: EMBL:EAW58224.1 xref: UniProtKB:Q15627 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018860 ! NR4A1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056086 name: TRBP2_HUMAN def: "TAR RNA-binding protein 2" [UniProtKB:Q15633] synonym: "Trans-activation-responsive RNA-binding protein" EXACT [UniProtKB:Q15633] xref: EMBL:AAA36765.1 xref: EMBL:AAB50581.2 xref: EMBL:AAH05860.1 xref: EMBL:AAP35804.1 xref: EMBL:EAW96720.1 xref: UniProtKB:Q12878 xref: UniProtKB:Q15633 xref: UniProtKB:Q9BRY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020347 ! TARBP2_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015984 ! dicer1-tarbp2-1 physical interaction relationship: participates_in CCO:I0017405 ! dicer1-tarbp2-2 direct interaction relationship: participates_in CCO:I0017406 ! tarbp2-dicer direct interaction relationship: participates_in CCO:I0018688 ! dicer1-tarbp2-4 physical interaction relationship: participates_in CCO:I0018689 ! dicer1-tarbp2-6 physical interaction relationship: participates_in CCO:I0019306 ! dicer1-tarbp2-8 physical interaction relationship: participates_in CCO:I0019459 ! dicer1-tarbp2-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0071531 ! TRBP2_HUMAN-Phosphoserine152 [Term] id: CCO:B0056087 name: Q15635_HUMAN def: "Oncogene" [UniProtKB:Q15635] xref: EMBL:CAA45110.1 xref: UniProtKB:Q15635 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021100 ! tre_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056088 name: Q15636_HUMAN def: "Transcription factor" [UniProtKB:Q15636] xref: EMBL:AAA36767.1 xref: UniProtKB:Q15636 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056089 name: SF01_HUMAN def: "Splicing factor 1" [UniProtKB:Q15637] synonym: "BBP" EXACT [UniProtKB:Q15637] synonym: "Mammalian branch point-binding protein mBBP" EXACT [UniProtKB:Q15637] synonym: "Transcription factor ZFM1" EXACT [UniProtKB:Q15637] synonym: "Zinc finger gene in MEN1 locus" EXACT [UniProtKB:Q15637] synonym: "Zinc finger protein 162" EXACT [UniProtKB:Q15637] xref: EMBL:AAB03514.1 xref: EMBL:AAB04033.1 xref: EMBL:AAH00773.1 xref: EMBL:AAH08080.1 xref: EMBL:AAH08724.1 xref: EMBL:AAH20217.1 xref: EMBL:AAH38446.1 xref: EMBL:BAA05116.1 xref: EMBL:BAA05117.1 xref: EMBL:CAA03883.1 xref: EMBL:CAA70018.1 xref: EMBL:CAA70019.1 xref: UniProtKB:Q14818 xref: UniProtKB:Q14819 xref: UniProtKB:Q15637 xref: UniProtKB:Q15913 xref: UniProtKB:Q8IY00 xref: UniProtKB:Q92744 xref: UniProtKB:Q92745 xref: UniProtKB:Q969H7 xref: UniProtKB:Q9BW01 xref: UniProtKB:Q9UEI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019871 ! SF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015134 ! plscr1-sf1 physical interaction relationship: participates_in CCO:I0015201 ! sf1-trim23 physical interaction relationship: participates_in CCO:I0015218 ! ddx17-sf1 physical interaction relationship: participates_in CCO:I0015226 ! sf1-wwp2 physical interaction relationship: participates_in CCO:I0015451 ! rbpms-sf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002860 ! negative regulation of smooth muscle cell proliferation relationship: transforms_into CCO:B0070387 ! SF01_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0070388 ! SF01_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0070389 ! SF01_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0070390 ! SF01_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0070391 ! SF01_HUMAN-Phosphotyrosine87 relationship: transforms_into CCO:B0070392 ! SF01_HUMAN-Phosphoserine89 [Term] id: CCO:B0056090 name: CIP4_HUMAN def: "Cdc42-interacting protein 4" [UniProtKB:Q15642] synonym: "hSTP" EXACT [UniProtKB:Q15642] synonym: "Protein Felic" EXACT [UniProtKB:Q15642] synonym: "Salt tolerant protein" EXACT [UniProtKB:Q15642] synonym: "Thyroid receptor-interacting protein 10" EXACT [UniProtKB:Q15642] synonym: "TRIP-10" EXACT [UniProtKB:Q15642] xref: EMBL:AAC41729.1 xref: EMBL:AAH13002.1 xref: EMBL:AAK77492.1 xref: EMBL:AAL89588.1 xref: EMBL:AAM46851.1 xref: EMBL:AAP35344.1 xref: EMBL:AAV38969.1 xref: EMBL:AAV43773.1 xref: EMBL:BAB88853.1 xref: EMBL:BAD96829.1 xref: EMBL:CAA04062.1 xref: EMBL:CAG38751.1 xref: UniProtKB:O15184 xref: UniProtKB:Q15642 xref: UniProtKB:Q53G22 xref: UniProtKB:Q5TZN1 xref: UniProtKB:Q6FI24 xref: UniProtKB:Q8NFL1 xref: UniProtKB:Q8TCY1 xref: UniProtKB:Q8TDX3 xref: UniProtKB:Q96RJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017367 ! TRIP10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014957 ! trip10-wbp11 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064356 ! CIP4_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0064357 ! CIP4_HUMAN-Phosphoserine299 relationship: transforms_into CCO:B0064358 ! CIP4_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0064359 ! CIP4_HUMAN-Phosphoserine351 [Term] id: CCO:B0056091 name: ZNHI3_HUMAN def: "Zinc finger HIT domain-containing protein 3" [UniProtKB:Q15649] synonym: "HNF-4a coactivator" EXACT [UniProtKB:Q15649] synonym: "Thyroid hormone receptor interactor 3" EXACT [UniProtKB:Q15649] synonym: "Thyroid receptor-interacting protein 3" EXACT [UniProtKB:Q15649] synonym: "TRIP-3" EXACT [UniProtKB:Q15649] xref: EMBL:AAC41737.1 xref: EMBL:AAH17931.1 xref: EMBL:AAM82423.1 xref: UniProtKB:Q15649 xref: UniProtKB:Q8WVJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020997 ! ZNHIT3_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072259 ! ZNHI3_HUMAN-Phosphoserine80 [Term] id: CCO:B0056092 name: TRIP4_HUMAN def: "Activating signal cointegrator 1" [UniProtKB:Q15650] synonym: "ASC-1" EXACT [UniProtKB:Q15650] synonym: "Thyroid receptor-interacting protein 4" EXACT [UniProtKB:Q15650] synonym: "TRIP-4" EXACT [UniProtKB:Q15650] xref: EMBL:AAC41738.1 xref: EMBL:AAF01278.1 xref: EMBL:AAH12448.1 xref: UniProtKB:Q15650 xref: UniProtKB:Q96ED7 xref: UniProtKB:Q9UKH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020361 ! TRIP4_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003472 ! ligand-dependent nuclear receptor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071564 ! TRIP4_HUMAN-Phosphotyrosine289 [Term] id: CCO:B0056093 name: JHD2C_HUMAN def: "Probable JmjC domain-containing histone demethylation protein 2C" [UniProtKB:Q15652] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q15652] synonym: "Jumonji domain-containing protein 1C" EXACT [UniProtKB:Q15652] synonym: "Thyroid receptor-interacting protein 8" EXACT [UniProtKB:Q15652] synonym: "TRIP-8" EXACT [UniProtKB:Q15652] xref: EMBL:AAC41741.1 xref: EMBL:BAA92618.1 xref: EMBL:BAB55015.1 xref: EMBL:CAD38578.1 xref: EMBL:CAD97921.1 xref: EMBL:CAI10947.1 xref: EMBL:CAI10948.1 xref: EMBL:CAI10950.1 xref: EMBL:CAI14188.1 xref: UniProtKB:Q15652 xref: UniProtKB:Q5SQZ8 xref: UniProtKB:Q5SQZ9 xref: UniProtKB:Q5SR00 xref: UniProtKB:Q7Z3E7 xref: UniProtKB:Q8N3U0 xref: UniProtKB:Q96KB9 xref: UniProtKB:Q9P2G7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018361 ! JMJD1C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067209 ! JHD2C_HUMAN-Phosphoserine373 relationship: transforms_into CCO:B0067210 ! JHD2C_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0067211 ! JHD2C_HUMAN-Phosphoserine379 relationship: transforms_into CCO:B0067212 ! JHD2C_HUMAN-Phosphoserine430 relationship: transforms_into CCO:B0067213 ! JHD2C_HUMAN-Phosphoserine638 relationship: transforms_into CCO:B0067214 ! JHD2C_HUMAN-Phosphoserine641 [Term] id: CCO:B0056094 name: RHOH_HUMAN def: "Rho-related GTP-binding protein RhoH precursor" [UniProtKB:Q15669] synonym: "GTP-binding protein TTF" EXACT [UniProtKB:Q15669] xref: EMBL:AAH14261.1 xref: EMBL:AAM21122.1 xref: EMBL:CAA84538.1 xref: UniProtKB:Q15669 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019733 ! RHOH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0002163 ! negative regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070012 ! RHOH_HUMAN-Cysteine methyl ester188 [Term] id: CCO:B0056095 name: TWST1_HUMAN def: "Twist-related protein 1" [UniProtKB:Q15672] synonym: "H-twist" EXACT [UniProtKB:Q15672] xref: EMBL:AAC50930.1 xref: EMBL:AAC60381.2 xref: EMBL:AAH36704.1 xref: EMBL:CAA62850.1 xref: EMBL:CAA67664.1 xref: EMBL:CAA71821.1 xref: UniProtKB:Q15672 xref: UniProtKB:Q92487 xref: UniProtKB:Q99804 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020385 ! TWIST1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056096 name: ZN174_HUMAN def: "Zinc finger protein 174" [UniProtKB:Q15697] synonym: "AW-1" EXACT [UniProtKB:Q15697] synonym: "Zinc finger and SCAN domain-containing protein 8" EXACT [UniProtKB:Q15697] xref: EMBL:AAB04897.1 xref: EMBL:AAH00876.1 xref: EMBL:AAH01161.1 xref: UniProtKB:Q15697 xref: UniProtKB:Q9BQ34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020639 ! ZNF174_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072058 ! ZN174_HUMAN-Phosphotyrosine382 [Term] id: CCO:B0056097 name: ALX1_HUMAN def: "ALX homeobox protein 1" [UniProtKB:Q15699] synonym: "CART-1" EXACT [UniProtKB:Q15699] synonym: "Cartilage homeoprotein 1" EXACT [UniProtKB:Q15699] xref: EMBL:AAB08960.1 xref: EMBL:AAH10923.1 xref: EMBL:CAD90155.1 xref: UniProtKB:Q15699 xref: UniProtKB:Q546C8 xref: UniProtKB:Q96FH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016954 ! ALX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015631 ! cart1-ipo13 physical interaction relationship: participates_in CCO:I0019409 ! cart1-cart1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056098 name: T22D1_HUMAN def: "TSC22 domain family protein 1" [UniProtKB:Q15714] synonym: "Cerebral protein 2" EXACT [UniProtKB:Q15714] synonym: "Regulatory protein TSC-22" EXACT [UniProtKB:Q15714] synonym: "TGFB-stimulated clone 22 homolog" EXACT [UniProtKB:Q15714] synonym: "Transforming growth factor beta-1-induced transcript 4 protein" EXACT [UniProtKB:Q15714] xref: EMBL:AAC50566.1 xref: EMBL:AAG53077.1 xref: EMBL:AAH00456.1 xref: EMBL:AAH16867.1 xref: EMBL:AAH69207.1 xref: EMBL:AAI05278.1 xref: EMBL:AAI46665.1 xref: EMBL:AAI46680.1 xref: EMBL:BAA07598.1 xref: EMBL:BAB46917.1 xref: EMBL:BAC02703.1 xref: EMBL:BAG35266.1 xref: EMBL:CAA10951.1 xref: EMBL:CAG32992.1 xref: EMBL:CAH10539.1 xref: EMBL:CAI12991.1 xref: EMBL:CAI16499.1 xref: EMBL:EAX08710.1 xref: UniProtKB:O00666 xref: UniProtKB:Q15714 xref: UniProtKB:Q6AHX5 xref: UniProtKB:Q6IBU1 xref: UniProtKB:Q8NCN1 xref: UniProtKB:Q96JS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020087 ! TSC22D1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056099 name: ELAV1_HUMAN def: "ELAV-like protein 1" [UniProtKB:Q15717] synonym: "Hu-antigen R" EXACT [UniProtKB:Q15717] synonym: "HuR" EXACT [UniProtKB:Q15717] xref: EMBL:AAB41913.1 xref: EMBL:AAH03376.1 xref: UniProtKB:Q15717 xref: UniProtKB:Q9BTT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017680 ! ELAVL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0015894 ! elavl1-elavl1 physical interaction relationship: participates_in CCO:P0002800 ! mRNA stabilization relationship: transforms_into CCO:B0064971 ! ELAV1_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0064972 ! ELAV1_HUMAN-arginine217 [Term] id: CCO:B0056100 name: LT4R1_HUMAN def: "Leukotriene B4 receptor 1" [UniProtKB:Q15722] synonym: "Chemoattractant receptor-like 1" EXACT [UniProtKB:Q15722] synonym: "G-protein coupled receptor 16" EXACT [UniProtKB:Q15722] synonym: "LTB4-R 1" EXACT [UniProtKB:Q15722] synonym: "P2Y purinoceptor 7" EXACT [UniProtKB:Q15722] synonym: "P2Y7" EXACT [UniProtKB:Q15722] xref: EMBL:AAB16747.1 xref: EMBL:AAC50628.1 xref: EMBL:AAH04545.1 xref: EMBL:AAP84348.1 xref: EMBL:BAA20423.1 xref: EMBL:BAA20424.1 xref: EMBL:BAB00611.1 xref: EMBL:CAA67001.1 xref: UniProtKB:Q13305 xref: UniProtKB:Q15722 xref: UniProtKB:Q92641 xref: UniProtKB:Q9BSU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018528 ! LTB4R_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000182 ! leukotriene B4 receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001314 ! leukotriene receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0056101 name: ELF2_HUMAN def: "ETS-related transcription factor Elf-2" [UniProtKB:Q15723] synonym: "E74-like factor 2" EXACT [UniProtKB:Q15723] synonym: "New ETS-related factor" EXACT [UniProtKB:Q15723] xref: EMBL:AAB37759.1 xref: EMBL:AAB37760.1 xref: EMBL:AAB37761.1 xref: EMBL:AAF67195.1 xref: EMBL:AAF67196.1 xref: EMBL:AAH34951.1 xref: EMBL:AAH65025.1 xref: UniProtKB:Q15723 xref: UniProtKB:Q15724 xref: UniProtKB:Q15725 xref: UniProtKB:Q6P1K5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017682 ! ELF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018090 ! nerf2-aml1-2 physical interaction relationship: participates_in CCO:I0018372 ! nerf2-aml1-1 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0064975 ! ELF2_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0064976 ! ELF2_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0064977 ! ELF2_HUMAN-Phosphoserine372 [Term] id: CCO:B0056102 name: NAB2_HUMAN def: "NGFI-A-binding protein 2" [UniProtKB:Q15742] synonym: "EGR-1-binding protein 2" EXACT [UniProtKB:Q15742] synonym: "Melanoma-associated delayed early response protein" EXACT [UniProtKB:Q15742] synonym: "Protein MADER" EXACT [UniProtKB:Q15742] xref: EMBL:AAC50589.1 xref: EMBL:AAF72545.1 xref: EMBL:AAH65931.1 xref: EMBL:CAA09472.1 xref: EMBL:CAA50318.1 xref: UniProtKB:O76006 xref: UniProtKB:Q14797 xref: UniProtKB:Q15742 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018708 ! NAB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0068430 ! NAB2_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0068431 ! NAB2_HUMAN-Phosphoserine159 relationship: transforms_into CCO:B0068432 ! NAB2_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0068433 ! NAB2_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0068434 ! NAB2_HUMAN-Phosphoserine479 [Term] id: CCO:B0056103 name: CEBPE_HUMAN def: "CCAAT/enhancer-binding protein epsilon" [UniProtKB:Q15744] synonym: "C/EBP epsilon" EXACT [UniProtKB:Q15744] xref: EMBL:AAC50708.1 xref: EMBL:AAC50709.1 xref: EMBL:AAC51130.1 xref: EMBL:AAH35797.2 xref: UniProtKB:Q15744 xref: UniProtKB:Q15745 xref: UniProtKB:Q8IYI2 xref: UniProtKB:Q99803 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017326 ! CEBPE_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056104 name: GPR19_HUMAN def: "Probable G-protein coupled receptor 19" [UniProtKB:Q15760] synonym: "GPR-NGA" EXACT [UniProtKB:Q15760] xref: EMBL:AAB00316.1 xref: EMBL:AAB49751.1 xref: UniProtKB:Q15760 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018006 ! GPR19_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056105 name: NPY5R_HUMAN def: "Neuropeptide Y receptor type 5" [UniProtKB:Q15761] synonym: "NPY-Y5 receptor" EXACT [UniProtKB:Q15761] synonym: "NPY5-R" EXACT [UniProtKB:Q15761] synonym: "NPYY5" EXACT [UniProtKB:Q15761] synonym: "Y5 receptor" EXACT [UniProtKB:Q15761] xref: EMBL:AAC50623.1 xref: EMBL:AAC50741.1 xref: EMBL:AAC51295.1 xref: EMBL:AAH42416.1 xref: EMBL:AAP84351.1 xref: EMBL:EAX04839.1 xref: UniProtKB:Q15761 xref: UniProtKB:Q6GTR7 xref: UniProtKB:Q92916 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018845 ! NPY5R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000156 ! peptide YY receptor activity relationship: has_function CCO:F0000157 ! pancreatic polypeptide receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056106 name: CD226_HUMAN def: "CD226 antigen precursor" [UniProtKB:Q15762] synonym: "CD226 antigen" EXACT [UniProtKB:Q15762] synonym: "DNAM-1" EXACT [UniProtKB:Q15762] synonym: "DNAX accessory molecule 1" EXACT [UniProtKB:Q15762] xref: EMBL:AAC50560.1 xref: EMBL:AAH74787.1 xref: EMBL:CAD61184.1 xref: UniProtKB:Q15762 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017290 ! CD226_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064139 ! CD226_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0064140 ! CD226_HUMAN-Phosphotyrosine322 [Term] id: CCO:B0056107 name: EFNB3_HUMAN def: "Ephrin-B3 precursor" [UniProtKB:Q15768] synonym: "EPH-related receptor transmembrane ligand ELK-L3" EXACT [UniProtKB:Q15768] synonym: "EPH-related receptor tyrosine kinase ligand 8" EXACT [UniProtKB:Q15768] synonym: "LERK-8" EXACT [UniProtKB:Q15768] xref: EMBL:AAB05170.1 xref: EMBL:AAC50707.1 xref: EMBL:AAC51203.1 xref: EMBL:AAH22499.1 xref: EMBL:AAH42944.1 xref: UniProtKB:O00680 xref: UniProtKB:Q15768 xref: UniProtKB:Q8TBH7 xref: UniProtKB:Q92875 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017663 ! EFNB3_human relationship: has_function CCO:F0001342 ! transmembrane-ephrin receptor activity relationship: has_function CCO:F0006259 ! ephrin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002759 ! ephrin receptor signaling pathway [Term] id: CCO:B0056108 name: RAB30_HUMAN def: "Ras-related protein Rab-30" [UniProtKB:Q15771] xref: EMBL:AAC50774.1 xref: EMBL:AAH14213.1 xref: EMBL:AAM21104.1 xref: EMBL:CAG46903.1 xref: UniProtKB:Q15771 xref: UniProtKB:Q6FGK1 xref: UniProtKB:Q96CI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019587 ! RAB30_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000376 ! Golgi stack relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056109 name: SPEG_HUMAN def: "Striated muscle preferentially expressed protein kinase" [UniProtKB:Q15772] synonym: "Aortic preferentially expressed protein 1" EXACT [UniProtKB:Q15772] synonym: "APEG-1" EXACT [UniProtKB:Q15772] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q15772] xref: EMBL:AAC50599.1 xref: EMBL:AAH06346.1 xref: EMBL:AAT80901.1 xref: EMBL:AAY15052.1 xref: EMBL:ABD61734.1 xref: EMBL:BAA92535.1 xref: EMBL:BAC86568.1 xref: EMBL:BAC87572.1 xref: EMBL:CAG46998.1 xref: UniProtKB:Q15772 xref: UniProtKB:Q27J74 xref: UniProtKB:Q695L1 xref: UniProtKB:Q6FGA6 xref: UniProtKB:Q6ZQW1 xref: UniProtKB:Q6ZTL8 xref: UniProtKB:Q9P2P9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020011 ! SPEG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0070791 ! SPEG_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0070792 ! SPEG_HUMAN-Phosphothreonine449 relationship: transforms_into CCO:B0070793 ! SPEG_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0070794 ! SPEG_HUMAN-Phosphoserine476 relationship: transforms_into CCO:B0070795 ! SPEG_HUMAN-Phosphothreonine599 relationship: transforms_into CCO:B0070796 ! SPEG_HUMAN-Phosphoserine1172 [Term] id: CCO:B0056110 name: ZN192_HUMAN def: "Zinc finger protein 192" [UniProtKB:Q15776] synonym: "LD5-1" EXACT [UniProtKB:Q15776] synonym: "Zinc finger protein with KRAB and SCAN domains 8" EXACT [UniProtKB:Q15776] xref: EMBL:AAB02260.1 xref: EMBL:AAC51656.1 xref: EMBL:AAH96282.1 xref: EMBL:AAH96283.1 xref: EMBL:AAH96284.1 xref: EMBL:CAC15901.1 xref: UniProtKB:Q15776 xref: UniProtKB:Q4VAR1 xref: UniProtKB:Q4VAR2 xref: UniProtKB:Q4VAR3 xref: UniProtKB:Q9H4T1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020647 ! ZNF192_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072060 ! ZN192_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0072061 ! ZN192_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0072062 ! ZN192_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0072063 ! ZN192_HUMAN-Phosphothreonine195 [Term] id: CCO:B0056111 name: NDF2_HUMAN def: "Neurogenic differentiation factor 2" [UniProtKB:Q15784] synonym: "NDRF" EXACT [UniProtKB:Q15784] synonym: "NeuroD-related factor" EXACT [UniProtKB:Q15784] synonym: "NeuroD2" EXACT [UniProtKB:Q15784] xref: EMBL:AAC26058.1 xref: EMBL:AAH22481.1 xref: EMBL:BAA77569.1 xref: UniProtKB:Q15784 xref: UniProtKB:Q8TBI7 xref: UniProtKB:Q9UQC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018735 ! NEUROD2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056112 name: NCOA1_HUMAN def: "Nuclear receptor coactivator 1" [UniProtKB:Q15788] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q15788] synonym: "NCoA-1" EXACT [UniProtKB:Q15788] synonym: "Protein Hin-2" EXACT [UniProtKB:Q15788] synonym: "Renal carcinoma antigen NY-REN-52" EXACT [UniProtKB:Q15788] synonym: "RIP160" EXACT [UniProtKB:Q15788] synonym: "SRC-1" EXACT [UniProtKB:Q15788] synonym: "Steroid receptor coactivator 1" EXACT [UniProtKB:Q15788] xref: EMBL:AAA64187.1 xref: EMBL:AAB50242.1 xref: EMBL:AAC50305.1 xref: EMBL:AAC50631.1 xref: EMBL:AAI11534.1 xref: EMBL:AAI11535.1 xref: EMBL:AAT47737.1 xref: EMBL:AAX93184.1 xref: EMBL:ABS29266.1 xref: EMBL:CAA04371.1 xref: EMBL:CAA04372.1 xref: EMBL:EAX00746.1 xref: UniProtKB:O00150 xref: UniProtKB:O43792 xref: UniProtKB:O43793 xref: UniProtKB:Q13071 xref: UniProtKB:Q13420 xref: UniProtKB:Q15788 xref: UniProtKB:Q2T9G5 xref: UniProtKB:Q53SX3 xref: UniProtKB:Q6GVI5 xref: UniProtKB:Q7KYV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018728 ! NCOA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0068467 ! NCOA1_HUMAN-Phosphoserine103 relationship: transforms_into CCO:B0068468 ! NCOA1_HUMAN-Phosphoserine372 relationship: transforms_into CCO:B0068469 ! NCOA1_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0068470 ! NCOA1_HUMAN-Phosphoserine517 relationship: transforms_into CCO:B0068471 ! NCOA1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0068472 ! NCOA1_HUMAN-Phosphoserine1033 relationship: transforms_into CCO:B0068473 ! NCOA1_HUMAN-Phosphothreonine1179 relationship: transforms_into CCO:B0068474 ! NCOA1_HUMAN-Phosphoserine1185 [Term] id: CCO:B0056113 name: SMAD2_HUMAN def: "Mothers against decapentaplegic homolog 2" [UniProtKB:Q15796] synonym: "hMAD-2" EXACT [UniProtKB:Q15796] synonym: "hSMAD2" EXACT [UniProtKB:Q15796] synonym: "JV18-1" EXACT [UniProtKB:Q15796] synonym: "Mad-related protein 2" EXACT [UniProtKB:Q15796] synonym: "Mothers against DPP homolog 2" EXACT [UniProtKB:Q15796] synonym: "SMAD 2" EXACT [UniProtKB:Q15796] xref: EMBL:AAB17054.1 xref: EMBL:AAB17087.1 xref: EMBL:AAC39657.1 xref: EMBL:AAC50789.1 xref: EMBL:AAC51918.1 xref: EMBL:AAH14840.1 xref: EMBL:AAH25699.1 xref: UniProtKB:Q15796 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019939 ! SMAD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019325 ! smad2-smad4-2 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070592 ! SMAD2_HUMAN-Phosphothreonine8 relationship: transforms_into CCO:B0070593 ! SMAD2_HUMAN-N6-acetyllysine19 relationship: transforms_into CCO:B0070594 ! SMAD2_HUMAN-Phosphothreonine220 relationship: transforms_into CCO:B0070595 ! SMAD2_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0070596 ! SMAD2_HUMAN-Phosphoserine245 relationship: transforms_into CCO:B0070597 ! SMAD2_HUMAN-Phosphoserine250 relationship: transforms_into CCO:B0070598 ! SMAD2_HUMAN-Phosphoserine255 relationship: transforms_into CCO:B0070599 ! SMAD2_HUMAN-Phosphoserine458 relationship: transforms_into CCO:B0070600 ! SMAD2_HUMAN-Phosphoserine465 relationship: transforms_into CCO:B0070601 ! SMAD2_HUMAN-Phosphoserine467 [Term] id: CCO:B0056114 name: SMAD1_HUMAN def: "Mothers against decapentaplegic homolog 1" [UniProtKB:Q15797] synonym: "BSP-1" EXACT [UniProtKB:Q15797] synonym: "hSMAD1" EXACT [UniProtKB:Q15797] synonym: "JV4-1" EXACT [UniProtKB:Q15797] synonym: "Mad-related protein 1" EXACT [UniProtKB:Q15797] synonym: "Mothers against DPP homolog 1" EXACT [UniProtKB:Q15797] synonym: "SMAD 1" EXACT [UniProtKB:Q15797] synonym: "Transforming growth factor-beta-signaling protein 1" EXACT [UniProtKB:Q15797] xref: EMBL:AAB06852.1 xref: EMBL:AAC50493.1 xref: EMBL:AAC50621.1 xref: EMBL:AAC50790.1 xref: EMBL:AAH01878.1 xref: EMBL:AAP36050.1 xref: UniProtKB:Q15797 xref: UniProtKB:Q16636 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019938 ! SMAD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: transforms_into CCO:B0070591 ! SMAD1_HUMAN-Phosphoserine465 [Term] id: CCO:B0056115 name: RK_HUMAN def: "Rhodopsin kinase precursor" [UniProtKB:Q15835] synonym: "EC 2.7.11.14" EXACT [UniProtKB:Q15835] synonym: "G protein-coupled receptor kinase 1" EXACT [UniProtKB:Q15835] synonym: "RK" EXACT [UniProtKB:Q15835] xref: EMBL:AAB05929.1 xref: EMBL:AAG50439.1 xref: EMBL:AAT00534.2 xref: EMBL:BAF82601.1 xref: UniProtKB:Q15835 xref: UniProtKB:Q53X14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019748 ! GRK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001112 ! rhodopsin mediated signaling pathway relationship: transforms_into CCO:B0070059 ! RK_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0070060 ! RK_HUMAN-Phosphoserine491 relationship: transforms_into CCO:B0070061 ! RK_HUMAN-Phosphothreonine492 relationship: transforms_into CCO:B0070062 ! RK_HUMAN-Cysteine methyl ester560 [Term] id: CCO:B0056116 name: ADIPO_HUMAN def: "Adiponectin precursor" [UniProtKB:Q15848] synonym: "30 kDa adipocyte complement-related protein" EXACT [UniProtKB:Q15848] synonym: "ACRP30" EXACT [UniProtKB:Q15848] synonym: "Adipocyte complement-related 30 kDa protein" EXACT [UniProtKB:Q15848] synonym: "Adipocyte, C1q and collagen domain-containing protein" EXACT [UniProtKB:Q15848] synonym: "Adipose most abundant gene transcript 1 protein" EXACT [UniProtKB:Q15848] synonym: "apM-1" EXACT [UniProtKB:Q15848] synonym: "Gelatin-binding protein" EXACT [UniProtKB:Q15848] xref: EMBL:AAH54496.1 xref: EMBL:AAH96308.1 xref: EMBL:AAH96309.1 xref: EMBL:AAH96310.1 xref: EMBL:AAH96311.1 xref: EMBL:BAA08227.1 xref: EMBL:BAA86716.1 xref: EMBL:CAB52413.1 xref: UniProtKB:Q15848 xref: UniProtKB:Q58EX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016917 ! ADIPOQ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002518 ! negative regulation of gluconeogenesis relationship: participates_in CCO:P0002616 ! positive regulation of fatty acid metabolic process relationship: transforms_into CCO:B0065412 ! ADIPO_HUMAN-5-hydroxylysine33 relationship: transforms_into CCO:B0065413 ! ADIPO_HUMAN-4-hydroxyproline44 relationship: transforms_into CCO:B0065414 ! ADIPO_HUMAN-4-hydroxyproline47 relationship: transforms_into CCO:B0065415 ! ADIPO_HUMAN-4-hydroxyproline53 relationship: transforms_into CCO:B0065416 ! ADIPO_HUMAN-5-hydroxylysine65 relationship: transforms_into CCO:B0065417 ! ADIPO_HUMAN-5-hydroxylysine68 relationship: transforms_into CCO:B0065418 ! ADIPO_HUMAN-4-hydroxyproline71 relationship: transforms_into CCO:B0065419 ! ADIPO_HUMAN-4-hydroxyproline76 relationship: transforms_into CCO:B0065420 ! ADIPO_HUMAN-5-hydroxylysine77 relationship: transforms_into CCO:B0065421 ! ADIPO_HUMAN-4-hydroxyproline91 relationship: transforms_into CCO:B0065422 ! ADIPO_HUMAN-4-hydroxyproline95 relationship: transforms_into CCO:B0065423 ! ADIPO_HUMAN-5-hydroxylysine101 [Term] id: CCO:B0056117 name: USF2_HUMAN def: "Upstream stimulatory factor 2" [UniProtKB:Q15853] synonym: "FIP" EXACT [UniProtKB:Q15853] synonym: "FOS-interacting protein" EXACT [UniProtKB:Q15853] synonym: "Major late transcription factor 2" EXACT [UniProtKB:Q15853] synonym: "Upstream transcription factor 2" EXACT [UniProtKB:Q15853] xref: EMBL:AAB24368.1 xref: EMBL:AAB51179.1 xref: EMBL:AAH49821.1 xref: EMBL:CAA62339.1 xref: EMBL:CAA62340.1 xref: EMBL:CAA62341.1 xref: EMBL:CAA68942.1 xref: EMBL:CAG38742.1 xref: UniProtKB:O00671 xref: UniProtKB:O00709 xref: UniProtKB:Q05750 xref: UniProtKB:Q07952 xref: UniProtKB:Q15851 xref: UniProtKB:Q15852 xref: UniProtKB:Q15853 xref: UniProtKB:Q6FI33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020422 ! USF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000433 ! regulation of transcription from RNA polymerase II promoter by glucose relationship: participates_in CCO:P0000435 ! positive regulation of transcription from RNA polymerase II promoter by glucose relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071752 ! USF2_HUMAN-Phosphothreonine293 [Term] id: CCO:B0056118 name: ZFHX3_HUMAN def: "Zinc finger homeobox protein 3" [UniProtKB:Q15911] synonym: "Alpha-fetoprotein enhancer-binding protein" EXACT [UniProtKB:Q15911] synonym: "AT motif-binding factor" EXACT [UniProtKB:Q15911] synonym: "AT-binding transcription factor 1" EXACT [UniProtKB:Q15911] synonym: "ZFH-3" EXACT [UniProtKB:Q15911] synonym: "Zinc finger homeodomain protein 3" EXACT [UniProtKB:Q15911] xref: EMBL:AAC14462.1 xref: EMBL:AAC31674.1 xref: EMBL:AAC79153.1 xref: EMBL:BAA01095.1 xref: UniProtKB:O15101 xref: UniProtKB:Q13719 xref: UniProtKB:Q15911 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020583 ! ZFHX3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0072010 ! ZFHX3_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0072011 ! ZFHX3_HUMAN-Phosphoserine571 relationship: transforms_into CCO:B0072012 ! ZFHX3_HUMAN-Phosphoserine1180 relationship: transforms_into CCO:B0072013 ! ZFHX3_HUMAN-Phosphoserine1197 relationship: transforms_into CCO:B0072014 ! ZFHX3_HUMAN-Phosphoserine1204 relationship: transforms_into CCO:B0072015 ! ZFHX3_HUMAN-Phosphoserine1590 [Term] id: CCO:B0056119 name: ZBTB6_HUMAN def: "Zinc finger and BTB domain-containing protein 6" [UniProtKB:Q15916] synonym: "Zinc finger protein 482" EXACT [UniProtKB:Q15916] synonym: "Zinc finger protein with interaction domain" EXACT [UniProtKB:Q15916] xref: EMBL:AAH37282.1 xref: EMBL:CAA57543.1 xref: UniProtKB:Q15916 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020570 ! ZBTB6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056120 name: ZN141_HUMAN def: "Zinc finger protein 141" [UniProtKB:Q15928] xref: EMBL:AAC37529.1 xref: EMBL:AAH74853.3 xref: UniProtKB:Q15928 xref: UniProtKB:Q6DK07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020629 ! ZNF141_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056121 name: ZNF77_HUMAN def: "Zinc finger protein 77" [UniProtKB:Q15935] synonym: "ZNFpT1" EXACT [UniProtKB:Q15935] xref: EMBL:AAH43354.2 xref: EMBL:AAH62561.1 xref: EMBL:CAA46337.1 xref: EMBL:CAB96946.1 xref: UniProtKB:Q15935 xref: UniProtKB:Q86XJ3 xref: UniProtKB:Q9NPP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020986 ! ZNF77_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056122 name: ZNF79_HUMAN def: "Zinc finger protein 79" [UniProtKB:Q15937] synonym: "ZNFpT7" EXACT [UniProtKB:Q15937] xref: EMBL:AAH62309.1 xref: EMBL:BAB70771.1 xref: EMBL:CAA46339.1 xref: EMBL:CAH72928.1 xref: UniProtKB:Q15937 xref: UniProtKB:Q5VVW1 xref: UniProtKB:Q96NV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020987 ! ZNF79_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056123 name: ZN124_HUMAN def: "Zinc finger protein 124" [UniProtKB:Q15973] synonym: "HZF-16" EXACT [UniProtKB:Q15973] xref: EMBL:AAB25346.1 xref: EMBL:AAB25347.1 xref: EMBL:AAH96349.1 xref: EMBL:AAH96350.1 xref: EMBL:AAH96351.1 xref: EMBL:AAH99661.1 xref: EMBL:CAI14564.1 xref: UniProtKB:Q15973 xref: UniProtKB:Q15974 xref: UniProtKB:Q4VAJ7 xref: UniProtKB:Q5T2V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020620 ! ZNF124_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056124 name: Q16002_HUMAN def: "Pp52 protein" [UniProtKB:Q16002] xref: EMBL:AAD13906.1 xref: UniProtKB:Q16002 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021101 ! pp52_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056125 name: Q16003_HUMAN def: "Lymphocyte-specific protein 1" [UniProtKB:Q16003] xref: EMBL:AAC00496.1 xref: UniProtKB:Q16003 xref: UniProtKB:Q16004 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018526 ! LSP1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056126 name: Q16161_HUMAN def: "Cellular adhesion regulatory molecule" [UniProtKB:Q16161] xref: EMBL:AAB30799.1 xref: UniProtKB:Q16161 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021066 ! CMAR_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0001245 ! regulation of cell adhesion [Term] id: CCO:B0056127 name: ENOX2_HUMAN def: "Ecto-NOX disulfide-thiol exchanger 2" [UniProtKB:Q16206] synonym: "APK1 antigen" EXACT [UniProtKB:Q16206] synonym: "Cytosolic ovarian carcinoma antigen 1" EXACT [UniProtKB:Q16206] synonym: "tNOX" EXACT [UniProtKB:Q16206] synonym: "Tumor-associated hydroquinone oxidase" EXACT [UniProtKB:Q16206] xref: EMBL:AAB30428.1 xref: EMBL:AAF20934.2 xref: EMBL:AAH19254.2 xref: EMBL:CAB61581.2 xref: EMBL:CAH71675.1 xref: EMBL:CAH71676.1 xref: EMBL:CAI43113.1 xref: EMBL:CAI43114.1 xref: UniProtKB:Q16206 xref: UniProtKB:Q5VTJ1 xref: UniProtKB:Q5VTJ2 xref: UniProtKB:Q8WUX0 xref: UniProtKB:Q9NTP6 xref: UniProtKB:Q9UH82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017712 ! ENOX2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0002532 ! protein disulfide oxidoreductase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015105 ! cova1-magea11 physical interaction relationship: participates_in CCO:I0015799 ! cova1-flj10094 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056128 name: Q16219_HUMAN def: "Insulin activator factor (Insulin control element-binding transcription factor)." [UniProtKB:Q16219] xref: EMBL:AAB31986.1 xref: UniProtKB:Q16219 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021102 ! INSAF_human relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000991 ! insulin control element activator complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056129 name: NF2L2_HUMAN def: "Nuclear factor erythroid 2-related factor 2" [UniProtKB:Q16236] synonym: "HEBP1" EXACT [UniProtKB:Q16236] synonym: "NF-E2-related factor 2" EXACT [UniProtKB:Q16236] synonym: "NFE2-related factor 2" EXACT [UniProtKB:Q16236] synonym: "Nuclear factor, erythroid derived 2, like 2" EXACT [UniProtKB:Q16236] xref: EMBL:AAB32188.1 xref: EMBL:AAH11558.1 xref: EMBL:AAY14710.1 xref: EMBL:BAD92023.1 xref: UniProtKB:Q16236 xref: UniProtKB:Q53RW6 xref: UniProtKB:Q59HH2 xref: UniProtKB:Q96F71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018763 ! NFE2L2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068602 ! NF2L2_HUMAN-Phosphoserine40 [Term] id: CCO:B0056130 name: Q16247_HUMAN def: "Histone H1 transcription factor large subunit 2A" [UniProtKB:Q16247] xref: EMBL:AAB32534.1 xref: UniProtKB:Q16247 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056131 name: IBP7_HUMAN def: "Insulin-like growth factor-binding protein 7 precursor" [UniProtKB:Q16270] synonym: "IBP-7" EXACT [UniProtKB:Q16270] synonym: "IGF-binding protein 7" EXACT [UniProtKB:Q16270] synonym: "IGFBP-7" EXACT [UniProtKB:Q16270] synonym: "IGFBP-rP1" EXACT [UniProtKB:Q16270] synonym: "MAC25 protein" EXACT [UniProtKB:Q16270] synonym: "PGI2-stimulating factor" EXACT [UniProtKB:Q16270] synonym: "Prostacyclin-stimulating factor" EXACT [UniProtKB:Q16270] xref: EMBL:AAA16187.1 xref: EMBL:AAB32370.1 xref: EMBL:AAH17201.1 xref: EMBL:AAH66339.1 xref: EMBL:AAP35300.1 xref: EMBL:AAR89912.1 xref: UniProtKB:Q07822 xref: UniProtKB:Q16270 xref: UniProtKB:Q53YE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018213 ! IGFBP7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0056132 name: CNGA3_HUMAN def: "Cyclic nucleotide-gated cation channel alpha-3" [UniProtKB:Q16281] synonym: "CNG channel alpha-3" EXACT [UniProtKB:Q16281] synonym: "CNG-3" EXACT [UniProtKB:Q16281] synonym: "CNG3" EXACT [UniProtKB:Q16281] synonym: "Cone photoreceptor cGMP-gated channel subunit alpha" EXACT [UniProtKB:Q16281] synonym: "Cyclic nucleotide-gated channel alpha-3" EXACT [UniProtKB:Q16281] xref: EMBL:AAC17440.1 xref: EMBL:AAD14208.1 xref: EMBL:AAH96298.1 xref: EMBL:AAH96300.1 xref: EMBL:AAY24181.1 xref: UniProtKB:Q16281 xref: UniProtKB:Q53RD2 xref: UniProtKB:Q9UP64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017399 ! CNGA3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0002733 ! ligand-gated ion channel activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056133 name: NTRK3_HUMAN def: "NT-3 growth factor receptor precursor" [UniProtKB:Q16288] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q16288] synonym: "GP145-TrkC" EXACT [UniProtKB:Q16288] synonym: "Neurotrophic tyrosine kinase receptor type 3" EXACT [UniProtKB:Q16288] synonym: "Trk-C" EXACT [UniProtKB:Q16288] synonym: "TrkC tyrosine kinase" EXACT [UniProtKB:Q16288] xref: EMBL:AAA75374.1 xref: EMBL:AAB33111.1 xref: EMBL:AAB33112.1 xref: EMBL:CAA12029.1 xref: UniProtKB:O75682 xref: UniProtKB:Q12827 xref: UniProtKB:Q16288 xref: UniProtKB:Q16289 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018887 ! NTRK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0068887 ! NTRK3_HUMAN-Phosphotyrosine516 relationship: transforms_into CCO:B0068888 ! NTRK3_HUMAN-Phosphotyrosine705 relationship: transforms_into CCO:B0068889 ! NTRK3_HUMAN-Phosphotyrosine709 relationship: transforms_into CCO:B0068890 ! NTRK3_HUMAN-Phosphotyrosine710 relationship: transforms_into CCO:B0068891 ! NTRK3_HUMAN-Phosphotyrosine834 [Term] id: CCO:B0056134 name: Q16293_HUMAN def: "Clone MM1 product" [UniProtKB:Q16293] xref: EMBL:AAB33781.1 xref: UniProtKB:Q16293 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021103 ! MM1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056135 name: Q16296_HUMAN def: "Microtubule-associated protein" [UniProtKB:Q16296] xref: EMBL:AAB33379.1 xref: UniProtKB:Q16296 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021104 ! 4R-MAP2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization [Term] id: CCO:B0056136 name: Q16365_HUMAN def: "GATA-4 transcription factor" [UniProtKB:Q16365] xref: EMBL:BAA11334.1 xref: UniProtKB:O00640 xref: UniProtKB:Q16365 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0056137 name: SSX1_HUMAN def: "Protein SSX1" [UniProtKB:Q16384] synonym: "Cancer/testis antigen 5.1" EXACT [UniProtKB:Q16384] synonym: "CT5.1" EXACT [UniProtKB:Q16384] synonym: "Synovial sarcoma, X breakpoint 1" EXACT [UniProtKB:Q16384] xref: EMBL:AAB35378.1 xref: EMBL:AAH01003.1 xref: EMBL:AAI25152.1 xref: EMBL:AAI28612.1 xref: EMBL:CAA60110.1 xref: EMBL:CAI41141.1 xref: UniProtKB:Q08AJ2 xref: UniProtKB:Q16384 xref: UniProtKB:Q5JQ64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020047 ! SSX1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070943 ! SSX1_HUMAN-Phosphoserine181 [Term] id: CCO:B0056138 name: SSX2_HUMAN def: "Protein SSX2" [UniProtKB:Q16385] synonym: "Cancer/testis antigen 5.2" EXACT [UniProtKB:Q16385] synonym: "CT5.2" EXACT [UniProtKB:Q16385] synonym: "HOM-MEL-40" EXACT [UniProtKB:Q16385] synonym: "SSX" EXACT [UniProtKB:Q16385] synonym: "Synovial sarcoma, X breakpoint 2" EXACT [UniProtKB:Q16385] xref: EMBL:AAB35379.1 xref: EMBL:AAB35674.1 xref: EMBL:AAH02818.1 xref: EMBL:AAH07343.1 xref: EMBL:AAH16957.1 xref: EMBL:AAH69313.1 xref: EMBL:AAH71827.1 xref: EMBL:AAI03864.1 xref: EMBL:CAA60111.1 xref: EMBL:CAI41151.1 xref: EMBL:CAI41152.1 xref: EMBL:CAI41157.1 xref: EMBL:CAI41158.1 xref: EMBL:CAI41623.1 xref: EMBL:CAI41624.1 xref: UniProtKB:Q16385 xref: UniProtKB:Q16404 xref: UniProtKB:Q5JS26 xref: UniProtKB:Q96IP7 xref: UniProtKB:Q9BU88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020048 ! SSX2_human relationship: encoded_by CCO:G0020049 ! SSX2B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056139 name: Q16503_HUMAN def: "Thyrotropin receptor-I" [UniProtKB:Q16503] xref: EMBL:AAB24246.1 xref: UniProtKB:Q16503 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056140 name: RPE65_HUMAN def: "Retinal pigment epithelium-specific 65 kDa protein" [UniProtKB:Q16518] xref: EMBL:AAA99012.1 xref: EMBL:AAC14586.1 xref: EMBL:AAC39660.1 xref: EMBL:AAH75035.1 xref: EMBL:AAH75036.1 xref: UniProtKB:Q16518 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019784 ! RPE65_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000795 ! regulation of rhodopsin gene expression relationship: transforms_into CCO:B0070161 ! RPE65_HUMAN-N-acetylserine2 [Term] id: CCO:B0056141 name: Q16525_HUMAN def: "C-H-ras-1 gene with novel codon 13 mutation (MDS N-ras oncogene exon 1 MDS " [UniProtKB:Q16525] xref: EMBL:CAA29078.1 xref: EMBL:CAA34461.1 xref: UniProtKB:Q16525 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056142 name: CRY1_HUMAN def: "Cryptochrome-1" [UniProtKB:Q16526] xref: EMBL:AAH30519.1 xref: EMBL:BAA12068.1 xref: EMBL:BAA12710.1 xref: UniProtKB:Q16526 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017466 ! CRY1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000417 ! DNA photolyase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001680 ! G-protein coupled photoreceptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0014998 ! cry1-plscr1 physical interaction relationship: participates_in CCO:I0015196 ! cry1-mdfi physical interaction relationship: participates_in CCO:I0015223 ! cry1-krtap4_12 physical interaction relationship: participates_in CCO:I0015622 ! cry1-traf2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064519 ! CRY1_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0064520 ! CRY1_HUMAN-Phosphotyrosine432 [Term] id: CCO:B0056143 name: CSRP2_HUMAN def: "Cysteine and glycine-rich protein 2" [UniProtKB:Q16527] synonym: "CRP2" EXACT [UniProtKB:Q16527] synonym: "Cysteine-rich protein 2" EXACT [UniProtKB:Q16527] synonym: "LIM domain only protein 5" EXACT [UniProtKB:Q16527] synonym: "SmLIM" EXACT [UniProtKB:Q16527] synonym: "Smooth muscle cell LIM protein" EXACT [UniProtKB:Q16527] xref: EMBL:AAC27344.1 xref: EMBL:AAC51753.1 xref: EMBL:AAC51755.1 xref: EMBL:AAH00992.1 xref: EMBL:AAV38716.1 xref: UniProtKB:Q16527 xref: UniProtKB:Q93030 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017486 ! CSRP2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0056144 name: SNPC1_HUMAN def: "snRNA-activating protein complex subunit 1" [UniProtKB:Q16533] synonym: "Proximal sequence element-binding transcription factor subunit gamma" EXACT [UniProtKB:Q16533] synonym: "PSE-binding factor subunit gamma" EXACT [UniProtKB:Q16533] synonym: "PTF subunit gamma" EXACT [UniProtKB:Q16533] synonym: "Small nuclear RNA-activating complex polypeptide 1" EXACT [UniProtKB:Q16533] synonym: "SNAPc 43 kDa subunit" EXACT [UniProtKB:Q16533] synonym: "SNAPc subunit 1" EXACT [UniProtKB:Q16533] synonym: "snRNA-activating protein complex 43 kDa subunit" EXACT [UniProtKB:Q16533] xref: EMBL:AAC50358.1 xref: EMBL:AAH14984.1 xref: EMBL:AAH19038.1 xref: EMBL:CAA87590.1 xref: UniProtKB:Q16533 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019964 ! SNAPC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070690 ! SNPC1_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0070691 ! SNPC1_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0070692 ! SNPC1_HUMAN-Phosphoserine292 [Term] id: CCO:B0056145 name: HLF_HUMAN def: "Hepatic leukemia factor" [UniProtKB:Q16534] xref: EMBL:AAA52675.1 xref: EMBL:AAA58445.1 xref: EMBL:AAH36093.1 xref: EMBL:CAA48777.1 xref: UniProtKB:Q16534 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018135 ! HLF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056146 name: GP162_HUMAN def: "Probable G-protein coupled receptor 162" [UniProtKB:Q16538] synonym: "Gene-rich cluster gene A protein" EXACT [UniProtKB:Q16538] xref: EMBL:AAB51310.1 xref: EMBL:AAB51311.1 xref: EMBL:AAC50463.1 xref: EMBL:AAC50466.1 xref: EMBL:AAH02353.1 xref: EMBL:AAH80585.1 xref: EMBL:BAD93073.1 xref: UniProtKB:Q16538 xref: UniProtKB:Q16664 xref: UniProtKB:Q59EH5 xref: UniProtKB:Q66K56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017984 ! GPR162_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056147 name: Q16544_HUMAN def: "Postmeiotic segregation increased 2-like protein 4." [UniProtKB:Q16544] xref: EMBL:BAA07473.1 xref: EMBL:BAA07512.1 xref: UniProtKB:Q16544 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021105 ! PMS2L4_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0056148 name: B2LA1_HUMAN def: "Bcl-2-related protein A1" [UniProtKB:Q16548] synonym: "Hemopoietic-specific early response protein" EXACT [UniProtKB:Q16548] synonym: "Protein BFL-1" EXACT [UniProtKB:Q16548] synonym: "Protein GRS" EXACT [UniProtKB:Q16548] xref: EMBL:AAC50288.1 xref: EMBL:AAC50438.1 xref: EMBL:AAH16281.1 xref: EMBL:AAP35767.1 xref: EMBL:CAA70566.1 xref: UniProtKB:Q16548 xref: UniProtKB:Q99524 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017109 ! BCL2A1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019474 ! bcl2a1-bid direct interaction relationship: participates_in CCO:I0019475 ! bcl2a1-bbc3 direct interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056149 name: LY6E_HUMAN def: "Lymphocyte antigen 6E precursor" [UniProtKB:Q16553] synonym: "Ly-6E" EXACT [UniProtKB:Q16553] synonym: "Retinoic acid-induced gene E protein" EXACT [UniProtKB:Q16553] synonym: "RIG-E" EXACT [UniProtKB:Q16553] synonym: "SCA-2" EXACT [UniProtKB:Q16553] synonym: "Stem cell antigen 2" EXACT [UniProtKB:Q16553] synonym: "Thymic shared antigen 1" EXACT [UniProtKB:Q16553] synonym: "TSA-1" EXACT [UniProtKB:Q16553] xref: EMBL:AAB07513.1 xref: EMBL:AAC50519.1 xref: EMBL:AAC50616.1 xref: EMBL:AAI19709.1 xref: EMBL:AAI19710.1 xref: EMBL:CAA92321.1 xref: UniProtKB:Q0VDE5 xref: UniProtKB:Q16553 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018532 ! LY6E_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0056150 name: DPYL2_HUMAN def: "Dihydropyrimidinase-related protein 2" [UniProtKB:Q16555] synonym: "Collapsin response mediator protein 2" EXACT [UniProtKB:Q16555] synonym: "CRMP-2" EXACT [UniProtKB:Q16555] synonym: "DRP-2" EXACT [UniProtKB:Q16555] synonym: "N2A3" EXACT [UniProtKB:Q16555] xref: EMBL:AAA93202.1 xref: EMBL:AAC05793.1 xref: EMBL:AAH56408.1 xref: EMBL:AAH67109.1 xref: EMBL:BAA11191.1 xref: EMBL:BAA86991.1 xref: UniProtKB:O00424 xref: UniProtKB:Q16555 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017614 ! DPYSL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017427 ! disc1-dpysl2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064862 ! DPYL2_HUMAN-Phosphotyrosine32 relationship: transforms_into CCO:B0064863 ! DPYL2_HUMAN-Phosphotyrosine431 relationship: transforms_into CCO:B0064864 ! DPYL2_HUMAN-Phosphothreonine462 relationship: transforms_into CCO:B0064865 ! DPYL2_HUMAN-Phosphoserine465 relationship: transforms_into CCO:B0064866 ! DPYL2_HUMAN-Phosphotyrosine499 relationship: transforms_into CCO:B0064867 ! DPYL2_HUMAN-Phosphothreonine509 relationship: transforms_into CCO:B0064868 ! DPYL2_HUMAN-Phosphothreonine514 relationship: transforms_into CCO:B0064869 ! DPYL2_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0064870 ! DPYL2_HUMAN-Phosphoserine522 [Term] id: CCO:B0056151 name: TAL2_HUMAN def: "T-cell acute lymphocytic leukemia protein 2" [UniProtKB:Q16559] synonym: "TAL-2" EXACT [UniProtKB:Q16559] xref: EMBL:AAA60613.1 xref: EMBL:AAC60629.1 xref: EMBL:AAH69422.1 xref: EMBL:AAI26374.1 xref: EMBL:AAI26376.1 xref: EMBL:CAC22163.1 xref: UniProtKB:A0AVI7 xref: UniProtKB:Q16559 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020144 ! TAL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056152 name: CART_HUMAN def: "Cocaine- and amphetamine-regulated transcript protein precursor" [UniProtKB:Q16568] xref: EMBL:AAB08010.1 xref: EMBL:AAB08011.1 xref: EMBL:AAH29882.1 xref: UniProtKB:Q16568 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017234 ! CARTPT_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000410 ! activation of MAPKK activity relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0001655 ! positive regulation of epinephrine secretion relationship: participates_in CCO:P0001713 ! circadian regulation of gene expression relationship: participates_in CCO:P0002485 ! negative regulation of osteoclast differentiation relationship: participates_in CCO:P0003174 ! positive regulation of transmission of nerve impulse [Term] id: CCO:B0056153 name: DUFFY_HUMAN def: "Duffy antigen/chemokine receptor" [UniProtKB:Q16570] synonym: "CD234 antigen" EXACT [UniProtKB:Q16570] synonym: "Fy glycoprotein" EXACT [UniProtKB:Q16570] synonym: "Glycoprotein D" EXACT [UniProtKB:Q16570] synonym: "GpFy" EXACT [UniProtKB:Q16570] synonym: "Plasmodium vivax receptor" EXACT [UniProtKB:Q16570] xref: EMBL:AAB33239.1 xref: EMBL:AAC50055.1 xref: EMBL:AAC72301.1 xref: EMBL:AAD20435.1 xref: EMBL:AAF02415.1 xref: EMBL:AAF02416.1 xref: EMBL:AAH17817.1 xref: EMBL:CAA59770.1 xref: EMBL:CAB56228.1 xref: UniProtKB:O75898 xref: UniProtKB:Q16300 xref: UniProtKB:Q16570 xref: UniProtKB:Q8WWE3 xref: UniProtKB:Q9UJP0 xref: UniProtKB:Q9UKZ5 xref: UniProtKB:Q9UKZ6 xref: UniProtKB:Q9UQE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017629 ! DARC_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056154 name: C3AR_HUMAN def: "C3a anaphylatoxin chemotactic receptor" [UniProtKB:Q16581] synonym: "C3a-R" EXACT [UniProtKB:Q16581] synonym: "C3AR" EXACT [UniProtKB:Q16581] xref: EMBL:AAC50374.1 xref: EMBL:AAC50657.1 xref: EMBL:AAH20742.1 xref: EMBL:AAP23198.1 xref: EMBL:AAR13862.1 xref: EMBL:BAC06088.1 xref: EMBL:CAA97504.1 xref: UniProtKB:O43771 xref: UniProtKB:Q16581 xref: UniProtKB:Q92868 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017196 ! C3AR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0064022 ! C3AR_HUMAN-Sulfotyrosine174 relationship: transforms_into CCO:B0064023 ! C3AR_HUMAN-Sulfotyrosine184 relationship: transforms_into CCO:B0064024 ! C3AR_HUMAN-Sulfotyrosine318 [Term] id: CCO:B0056155 name: ZNF74_HUMAN def: "Zinc finger protein 74" [UniProtKB:Q16587] synonym: "hZNF7" EXACT [UniProtKB:Q16587] xref: EMBL:AAF21777.1 xref: EMBL:AAF21778.1 xref: EMBL:AAF21779.1 xref: EMBL:AAF21780.1 xref: EMBL:CAA50632.1 xref: EMBL:CAA63379.1 xref: EMBL:CAC16149.1 xref: EMBL:CAG30502.1 xref: UniProtKB:Q16587 xref: UniProtKB:Q6IBV2 xref: UniProtKB:Q9UC04 xref: UniProtKB:Q9UF05 xref: UniProtKB:Q9UF06 xref: UniProtKB:Q9UF07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020984 ! ZNF74_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056156 name: Q16590_HUMAN def: "PMS8 protein (HCG2023604, isoform CRA_a) (HPMS8 protein)" [UniProtKB:Q16590] xref: EMBL:BAA07475.1 xref: EMBL:BAA07515.1 xref: EMBL:EAW76559.1 xref: UniProtKB:Q16590 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021106 ! PMS8_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0056157 name: ZN239_HUMAN def: "Zinc finger protein 239" [UniProtKB:Q16600] synonym: "HOK-2" EXACT [UniProtKB:Q16600] synonym: "Zinc finger protein MOK-2" EXACT [UniProtKB:Q16600] xref: EMBL:AAH26030.1 xref: EMBL:CAA57637.1 xref: EMBL:CAA57638.1 xref: EMBL:CAI15021.1 xref: UniProtKB:Q16600 xref: UniProtKB:Q5T1G9 xref: UniProtKB:Q8TAS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020676 ! ZNF239_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072073 ! ZN239_HUMAN-Phosphoserine41 [Term] id: CCO:B0056158 name: ECM1_HUMAN def: "Extracellular matrix protein 1 precursor" [UniProtKB:Q16610] synonym: "Secretory component p85" EXACT [UniProtKB:Q16610] xref: EMBL:AAB05933.1 xref: EMBL:AAB05934.1 xref: EMBL:AAB88081.1 xref: UniProtKB:Q16610 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017653 ! ECM1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:I0018936 ! atn1-ecm1 physical interaction relationship: participates_in CCO:I0019164 ! rere-ecm1 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0056159 name: NP311_HUMAN def: "Neuronal protein 3.1" [UniProtKB:Q16612] synonym: "Protein p311" EXACT [UniProtKB:Q16612] xref: EMBL:AAA74903.1 xref: EMBL:AAA93255.1 xref: EMBL:AAH11050.1 xref: EMBL:AAH19068.1 xref: EMBL:AAH72013.1 xref: EMBL:AAH72443.1 xref: UniProtKB:Q16612 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018826 ! C5orf13_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020260 ! c5orf13-igsf21 physical interaction relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0056160 name: CTF1_HUMAN def: "Cardiotrophin-1" [UniProtKB:Q16619] synonym: "CT-1" EXACT [UniProtKB:Q16619] xref: EMBL:AAA85229.1 xref: EMBL:AAD12173.1 xref: EMBL:AAH64416.1 xref: UniProtKB:Q16619 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017489 ! CTF1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001448 ! leukemia inhibitory factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0056161 name: NTRK2_HUMAN def: "BDNF/NT-3 growth factors receptor precursor" [UniProtKB:Q16620] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q16620] synonym: "GP145-TrkB" EXACT [UniProtKB:Q16620] synonym: "Neurotrophic tyrosine kinase receptor type 2" EXACT [UniProtKB:Q16620] synonym: "Trk-B" EXACT [UniProtKB:Q16620] synonym: "TrkB tyrosine kinase" EXACT [UniProtKB:Q16620] xref: EMBL:AAB33109.1 xref: EMBL:AAB33110.1 xref: EMBL:AAC51371.1 xref: EMBL:AAH31835.1 xref: EMBL:AAL67966.1 xref: EMBL:AAM77876.1 xref: EMBL:CAA53571.1 xref: UniProtKB:Q16620 xref: UniProtKB:Q16675 xref: UniProtKB:Q8WXJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018886 ! NTRK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0068882 ! NTRK2_HUMAN-Phosphotyrosine516 relationship: transforms_into CCO:B0068883 ! NTRK2_HUMAN-Phosphotyrosine702 relationship: transforms_into CCO:B0068884 ! NTRK2_HUMAN-Phosphotyrosine706 relationship: transforms_into CCO:B0068885 ! NTRK2_HUMAN-Phosphotyrosine707 relationship: transforms_into CCO:B0068886 ! NTRK2_HUMAN-Phosphotyrosine817 [Term] id: CCO:B0056162 name: NFE2_HUMAN def: "Transcription factor NF-E2 45 kDa subunit" [UniProtKB:Q16621] synonym: "Leucine zipper protein NF-E2" EXACT [UniProtKB:Q16621] synonym: "Nuclear factor, erythroid-derived 2 45 kDa subunit" EXACT [UniProtKB:Q16621] synonym: "p45 NF-E2" EXACT [UniProtKB:Q16621] xref: EMBL:AAA16118.1 xref: EMBL:AAA35612.1 xref: EMBL:AAB34115.1 xref: EMBL:AAH05044.1 xref: EMBL:AAP35952.1 xref: EMBL:ABC79302.1 xref: EMBL:CAG29280.1 xref: UniProtKB:Q07720 xref: UniProtKB:Q16621 xref: UniProtKB:Q6ICV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018771 ! NFE2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020625 ! phyhip-nfe2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056163 name: STX1A_HUMAN def: "Syntaxin-1A" [UniProtKB:Q16623] synonym: "Neuron-specific antigen HPC-1" EXACT [UniProtKB:Q16623] xref: EMBL:AAA20940.1 xref: EMBL:AAA53519.1 xref: EMBL:AAB65500.2 xref: EMBL:AAH03011.1 xref: EMBL:AAH64644.1 xref: EMBL:AAK54507.2 xref: EMBL:BAA07151.1 xref: UniProtKB:O15447 xref: UniProtKB:O15448 xref: UniProtKB:Q12936 xref: UniProtKB:Q16623 xref: UniProtKB:Q9BPZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020078 ! STX1A_human relationship: has_function CCO:F0001631 ! SNAP receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019625 ! snap25-stx1a physical interaction relationship: participates_in CCO:I0019626 ! stx1a-snap25 physical interaction relationship: participates_in CCO:I0019978 ! dnmt2-stx1a physical interaction relationship: participates_in CCO:I0020177 ! stx1a-vim physical interaction relationship: participates_in CCO:P0002956 ! regulation of insulin secretion relationship: transforms_into CCO:B0070986 ! STX1A_HUMAN-Phosphoserine14 [Term] id: CCO:B0056164 name: CCL14_HUMAN def: "C-C motif chemokine 14 precursor" [UniProtKB:Q16627] synonym: "Chemokine CC-1/CC-3" EXACT [UniProtKB:Q16627] synonym: "HCC-1(1-74)" EXACT [UniProtKB:Q16627] synonym: "HCC-1/HCC-3" EXACT [UniProtKB:Q16627] synonym: "NCC-2" EXACT [UniProtKB:Q16627] synonym: "Small-inducible cytokine A14" EXACT [UniProtKB:Q16627] xref: EMBL:AAC63329.1 xref: EMBL:AAF23982.1 xref: EMBL:AAH38289.1 xref: EMBL:AAH45165.1 xref: EMBL:CAA89263.1 xref: EMBL:CAA89264.1 xref: EMBL:CAA94307.1 xref: EMBL:CAA94309.1 xref: UniProtKB:Q13954 xref: UniProtKB:Q16627 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017260 ! CCL14_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0056165 name: OBF1_HUMAN def: "POU domain class 2-associating factor 1" [UniProtKB:Q16633] synonym: "B-cell-specific coactivator OBF-1" EXACT [UniProtKB:Q16633] synonym: "BOB-1" EXACT [UniProtKB:Q16633] synonym: "OCA-B" EXACT [UniProtKB:Q16633] synonym: "OCT-binding factor 1" EXACT [UniProtKB:Q16633] xref: EMBL:AAH32549.1 xref: EMBL:CAA58494.1 xref: EMBL:CAA87630.1 xref: EMBL:CAA89053.1 xref: UniProtKB:Q14983 xref: UniProtKB:Q16633 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019037 ! POU2AF1_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017719 ! syk-pou2af1 colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056166 name: MAPK3_HUMAN def: "MAP kinase-activated protein kinase 3" [UniProtKB:Q16644] synonym: "3pK" EXACT [UniProtKB:Q16644] synonym: "Chromosome 3p kinase" EXACT [UniProtKB:Q16644] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q16644] synonym: "MAPK-activated protein kinase 3" EXACT [UniProtKB:Q16644] synonym: "MAPKAP kinase 3" EXACT [UniProtKB:Q16644] synonym: "MAPKAPK-3" EXACT [UniProtKB:Q16644] xref: EMBL:AAC50428.1 xref: EMBL:AAD09136.1 xref: EMBL:AAH01662.1 xref: EMBL:AAH07591.1 xref: EMBL:AAH10407.1 xref: UniProtKB:Q16644 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018569 ! MAPKAPK3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001074 ! MAP kinase kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:B0056167 name: NFIL3_HUMAN def: "Nuclear factor interleukin-3-regulated protein" [UniProtKB:Q16649] synonym: "E4 promoter binding-protein 4" EXACT [UniProtKB:Q16649] synonym: "Interleukin-3 binding-protein 1" EXACT [UniProtKB:Q16649] synonym: "Interleukin-3 promoter transcriptional activator" EXACT [UniProtKB:Q16649] synonym: "Transcriptional activator NF-IL3A" EXACT [UniProtKB:Q16649] xref: EMBL:AAA93067.1 xref: EMBL:AAB35410.1 xref: EMBL:AAH08197.1 xref: EMBL:ABK15691.1 xref: EMBL:CAA45597.1 xref: EMBL:CAG46846.1 xref: EMBL:CAH73854.1 xref: UniProtKB:Q14211 xref: UniProtKB:Q16649 xref: UniProtKB:Q6FGQ8 xref: UniProtKB:Q96HS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018775 ! NFIL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068656 ! NFIL3_HUMAN-Phosphoserine286 relationship: transforms_into CCO:B0068657 ! NFIL3_HUMAN-Phosphoserine301 [Term] id: CCO:B0056168 name: TBR1_HUMAN def: "T-box brain protein 1" [UniProtKB:Q16650] synonym: "T-brain-1" EXACT [UniProtKB:Q16650] synonym: "TBR-1" EXACT [UniProtKB:Q16650] synonym: "TES-56" EXACT [UniProtKB:Q16650] xref: EMBL:AAA92010.1 xref: EMBL:AAI04845.1 xref: EMBL:AAI13419.1 xref: EMBL:AAY15017.1 xref: UniProtKB:Q14DC5 xref: UniProtKB:Q16650 xref: UniProtKB:Q53TH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020191 ! TBR1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056169 name: NRF1_HUMAN def: "Nuclear respiratory factor 1" [UniProtKB:Q16656] synonym: "Alpha palindromic-binding protein" EXACT [UniProtKB:Q16656] synonym: "Alpha-pal" EXACT [UniProtKB:Q16656] synonym: "NRF-1" EXACT [UniProtKB:Q16656] xref: EMBL:AAA16918.1 xref: EMBL:AAA21647.1 xref: EMBL:AAA79013.1 xref: UniProtKB:Q15305 xref: UniProtKB:Q16656 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018866 ! NRF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068829 ! NRF1_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0068830 ! NRF1_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0068831 ! NRF1_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0068832 ! NRF1_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0068833 ! NRF1_HUMAN-Phosphoserine52 [Term] id: CCO:B0056170 name: FSCN1_HUMAN def: "Fascin" [UniProtKB:Q16658] synonym: "55 kDa actin-bundling protein" EXACT [UniProtKB:Q16658] synonym: "p55" EXACT [UniProtKB:Q16658] synonym: "Singed-like protein" EXACT [UniProtKB:Q16658] xref: EMBL:AAA62201.1 xref: EMBL:AAA86442.1 xref: EMBL:AAH00521.1 xref: EMBL:AAH06304.1 xref: EMBL:AAH07643.1 xref: EMBL:AAH07948.1 xref: EMBL:AAH07988.1 xref: EMBL:AAL01526.1 xref: EMBL:AAP35282.1 xref: EMBL:EAW87346.1 xref: UniProtKB:A6NI89 xref: UniProtKB:Q16658 xref: UniProtKB:Q96IC5 xref: UniProtKB:Q9BRF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017839 ! FSCN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0019972 ! dnajb9-fscn1 physical interaction relationship: participates_in CCO:I0020422 ! rab1a-fscn1 physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0066285 ! FSCN1_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0066286 ! FSCN1_HUMAN-Phosphoserine38 relationship: transforms_into CCO:B0066287 ! FSCN1_HUMAN-Phosphoserine39 [Term] id: CCO:B0056171 name: CCL15_HUMAN def: "C-C motif chemokine 15 precursor" [UniProtKB:Q16663] synonym: "Chemokine CC-2" EXACT [UniProtKB:Q16663] synonym: "HCC-2" EXACT [UniProtKB:Q16663] synonym: "Leukotactin-1" EXACT [UniProtKB:Q16663] synonym: "LKN-1" EXACT [UniProtKB:Q16663] synonym: "Macrophage inflammatory protein 5" EXACT [UniProtKB:Q16663] synonym: "MIP-1 delta" EXACT [UniProtKB:Q16663] synonym: "MIP-5" EXACT [UniProtKB:Q16663] synonym: "Mrp-2b" EXACT [UniProtKB:Q16663] synonym: "NCC-3" EXACT [UniProtKB:Q16663] synonym: "Small-inducible cytokine A15" EXACT [UniProtKB:Q16663] xref: EMBL:AAB94617.1 xref: EMBL:AAC63328.1 xref: EMBL:AAD10847.1 xref: EMBL:CAA94306.1 xref: EMBL:CAA94308.1 xref: UniProtKB:Q16663 xref: UniProtKB:Q9UM74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017261 ! CCL15_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0005617 ! chemoattractant activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056172 name: IF16_HUMAN def: "Gamma-interferon-inducible protein Ifi-16" [UniProtKB:Q16666] synonym: "IFI 16" EXACT [UniProtKB:Q16666] synonym: "Interferon-inducible myeloid differentiation transcriptional activator" EXACT [UniProtKB:Q16666] xref: EMBL:AAA58683.1 xref: EMBL:AAB32519.2 xref: EMBL:AAF20997.1 xref: EMBL:AAH17059.1 xref: EMBL:AAM96005.1 xref: EMBL:BAC04462.1 xref: EMBL:BAD92226.1 xref: EMBL:CAI15081.1 xref: EMBL:CAI15082.1 xref: EMBL:CAI15083.1 xref: EMBL:CAI15084.1 xref: EMBL:CAI15085.1 xref: EMBL:CAI15086.1 xref: UniProtKB:Q16666 xref: UniProtKB:Q59GX0 xref: UniProtKB:Q5T3W7 xref: UniProtKB:Q5T3W8 xref: UniProtKB:Q5T3X0 xref: UniProtKB:Q5T3X1 xref: UniProtKB:Q5T3X2 xref: UniProtKB:Q8N9E5 xref: UniProtKB:Q8NEQ7 xref: UniProtKB:Q96AJ5 xref: UniProtKB:Q9UH78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018219 ! IFI16_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis relationship: transforms_into CCO:B0067005 ! IF16_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0067006 ! IF16_HUMAN-Phosphoserine153 [Term] id: CCO:B0056173 name: ZN187_HUMAN def: "Zinc finger protein 187" [UniProtKB:Q16670] synonym: "Protein SRE-ZBP" EXACT [UniProtKB:Q16670] synonym: "Zinc finger and SCAN domain-containing protein 26" EXACT [UniProtKB:Q16670] xref: EMBL:AAH13951.1 xref: EMBL:AAH13962.1 xref: EMBL:CAA77818.1 xref: EMBL:CAD97775.1 xref: EMBL:CAI46119.1 xref: UniProtKB:Q16670 xref: UniProtKB:Q5JPG4 xref: UniProtKB:Q7Z3Q6 xref: UniProtKB:Q96A17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020645 ! ZNF187_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056174 name: Q16673_HUMAN def: "PMS7 protein (HPMS7 protein)" [UniProtKB:Q16673] xref: EMBL:BAA07474.1 xref: EMBL:BAA07513.1 xref: UniProtKB:Q16673 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021107 ! PMS7_human relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0056175 name: MIA_HUMAN def: "Melanoma-derived growth regulatory protein precursor" [UniProtKB:Q16674] synonym: "Melanoma inhibitory activity" EXACT [UniProtKB:Q16674] xref: EMBL:AAH05910.1 xref: EMBL:AAP35693.1 xref: EMBL:CAA53203.1 xref: EMBL:CAA59195.1 xref: UniProtKB:Q16674 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018616 ! MIA_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0056176 name: DGKD_HUMAN def: "Diacylglycerol kinase delta" [UniProtKB:Q16760] synonym: "130 kDa diacylglycerol kinase" EXACT [UniProtKB:Q16760] synonym: "DAG kinase delta" EXACT [UniProtKB:Q16760] synonym: "DGK-delta" EXACT [UniProtKB:Q16760] synonym: "Diglyceride kinase delta" EXACT [UniProtKB:Q16760] synonym: "EC 2.7.1.107" EXACT [UniProtKB:Q16760] xref: EMBL:AAH06561.1 xref: EMBL:BAA09766.3 xref: EMBL:BAA11134.1 xref: EMBL:BAC11809.1 xref: UniProtKB:Q14158 xref: UniProtKB:Q16760 xref: UniProtKB:Q6PK55 xref: UniProtKB:Q8NG53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017566 ! DGKD_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:I0020289 ! dgkd-hs1bp1 physical interaction relationship: participates_in CCO:I0020290 ! dgkd-igsf21 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001148 ! second-messenger-mediated signaling [Term] id: CCO:B0056177 name: RTN1_HUMAN def: "Reticulon-1" [UniProtKB:Q16799] synonym: "Neuroendocrine-specific protein" EXACT [UniProtKB:Q16799] xref: EMBL:AAA59950.1 xref: EMBL:AAA59951.1 xref: EMBL:AAA59952.1 xref: EMBL:AAH90862.1 xref: UniProtKB:Q16799 xref: UniProtKB:Q16800 xref: UniProtKB:Q16801 xref: UniProtKB:Q5BKZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019811 ! RTN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070257 ! RTN1_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0070258 ! RTN1_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0070259 ! RTN1_HUMAN-Phosphoserine487 [Term] id: CCO:B0056178 name: DDR2_HUMAN def: "Discoidin domain-containing receptor 2 precursor" [UniProtKB:Q16832] synonym: "CD167 antigen-like family member B" EXACT [UniProtKB:Q16832] synonym: "CD167b antigen" EXACT [UniProtKB:Q16832] synonym: "Discoidin domain receptor 2" EXACT [UniProtKB:Q16832] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q16832] synonym: "Neurotrophic tyrosine kinase, receptor-related 3" EXACT [UniProtKB:Q16832] synonym: "Receptor protein-tyrosine kinase TKT" EXACT [UniProtKB:Q16832] synonym: "Tyrosine-protein kinase TYRO10" EXACT [UniProtKB:Q16832] xref: EMBL:AAH52998.1 xref: EMBL:BAG37013.1 xref: EMBL:BAG53183.1 xref: EMBL:CAA52777.1 xref: EMBL:CAI15941.1 xref: EMBL:EAW90713.1 xref: UniProtKB:Q16832 xref: UniProtKB:Q7Z730 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017542 ! DDR2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0064690 ! DDR2_HUMAN-Phosphotyrosine736 relationship: transforms_into CCO:B0064691 ! DDR2_HUMAN-Phosphotyrosine740 [Term] id: CCO:B0056179 name: TRXR1_HUMAN def: "Thioredoxin reductase 1, cytoplasmic" [UniProtKB:Q16881] synonym: "EC 1.8.1.9" EXACT [UniProtKB:Q16881] synonym: "Gene associated with retinoid-IFN-induced mortality 12 protein" EXACT [UniProtKB:Q16881] synonym: "GRIM-12" EXACT [UniProtKB:Q16881] synonym: "KM-102-derived reductase-like factor" EXACT [UniProtKB:Q16881] synonym: "Thioredoxin reductase TR1" EXACT [UniProtKB:Q16881] synonym: "TR" EXACT [UniProtKB:Q16881] xref: EMBL:AAB35418.1 xref: EMBL:AAC69621.1 xref: EMBL:AAF15900.1 xref: EMBL:AAH18122.2 xref: EMBL:AAL15432.1 xref: EMBL:AAQ62461.1 xref: EMBL:AAQ62462.1 xref: EMBL:AAQ62463.1 xref: EMBL:AAQ62464.1 xref: EMBL:AAQ62465.1 xref: EMBL:AAQ62466.1 xref: EMBL:AAQ62467.1 xref: EMBL:AAQ62468.1 xref: EMBL:AAQ62469.1 xref: EMBL:AAQ62470.1 xref: EMBL:AAQ62471.1 xref: EMBL:AAQ62472.1 xref: EMBL:AAQ62473.1 xref: EMBL:AAV38446.1 xref: EMBL:AAZ67916.1 xref: EMBL:BAA13674.1 xref: EMBL:CAA04503.1 xref: EMBL:CAA62629.1 xref: EMBL:CAG38744.1 xref: UniProtKB:Q16881 xref: UniProtKB:Q6FI31 xref: UniProtKB:Q6VB40 xref: UniProtKB:Q6VB41 xref: UniProtKB:Q6VB42 xref: UniProtKB:Q6VBP2 xref: UniProtKB:Q6VBP3 xref: UniProtKB:Q6VBP4 xref: UniProtKB:Q6VBP5 xref: UniProtKB:Q6VBP9 xref: UniProtKB:Q6VBQ0 xref: UniProtKB:Q6YNQ1 xref: UniProtKB:Q76P53 xref: UniProtKB:Q7LA96 xref: UniProtKB:Q8WVC8 xref: UniProtKB:Q99475 xref: UniProtKB:Q9UES8 xref: UniProtKB:Q9UH79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020364 ! TXNRD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020119 ! ppp1r16a-txnrd1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0071590 ! TRXR1_HUMAN-Phosphotyrosine161 relationship: transforms_into CCO:B0071591 ! TRXR1_HUMAN-Phosphotyrosine163 relationship: transforms_into CCO:B0071592 ! TRXR1_HUMAN-Phosphotyrosine281 relationship: transforms_into CCO:B0071593 ! TRXR1_HUMAN-Phosphotyrosine572 [Term] id: CCO:B0056180 name: YE008_HUMAN def: "Putative KRAB domain-containing protein LOC134466" [UniProtKB:Q17R26] xref: EMBL:AAI17491.1 xref: EMBL:AAI26475.1 xref: UniProtKB:A6NC11 xref: UniProtKB:Q17R26 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056181 name: Q17R53_HUMAN def: "Olfactory receptor, family 51, subfamily B, member 2" [UniProtKB:Q17R53] xref: EMBL:AAI17462.1 xref: UniProtKB:Q17R53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018983 ! OR51B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056182 name: Q17R96_HUMAN def: "GPR20 protein (G protein-coupled receptor 20)" [UniProtKB:Q17R96] xref: EMBL:AAI17410.1 xref: EMBL:EAW92227.1 xref: UniProtKB:Q17R96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018008 ! GPR20_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056183 name: ZN827_HUMAN def: "Zinc finger protein 827" [UniProtKB:Q17R98] xref: EMBL:AAI17408.1 xref: EMBL:AAP97679.1 xref: EMBL:BAC03591.1 xref: UniProtKB:Q17R98 xref: UniProtKB:Q7Z4S7 xref: UniProtKB:Q8N279 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020955 ! ZNF827_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056184 name: Q17RJ3_HUMAN def: "Zinc finger protein 285A" [UniProtKB:Q17RJ3] xref: EMBL:AAI17301.1 xref: EMBL:AAI17303.1 xref: UniProtKB:Q17RJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021108 ! ZNF285A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056185 name: TIGD6_HUMAN def: "Tigger transposable element-derived protein 6" [UniProtKB:Q17RP2] xref: EMBL:AAI17250.1 xref: EMBL:BAB71230.1 xref: EMBL:CAB66474.1 xref: EMBL:CAG38590.1 xref: UniProtKB:Q17RP2 xref: UniProtKB:Q96MQ4 xref: UniProtKB:Q9H0X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020270 ! TIGD6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056186 name: Q17RR2_HUMAN def: "Intelectin 2" [UniProtKB:Q17RR2] xref: EMBL:AAI17226.1 xref: UniProtKB:Q17RR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018347 ! ITLN2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056187 name: Q17RU2_HUMAN def: "REL protein" [UniProtKB:Q17RU2] xref: EMBL:AAI17192.1 xref: UniProtKB:Q17RU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019667 ! REL_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056188 name: Q17S04_HUMAN def: "Microtubule-associated protein" [UniProtKB:Q17S04] xref: EMBL:AAI10424.1 xref: EMBL:AAI17124.1 xref: EMBL:EAW70459.1 xref: UniProtKB:Q17S04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014816 ! MAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization [Term] id: CCO:B0056189 name: Q17S10_HUMAN def: "ADCYAP1R1 protein" [UniProtKB:Q17S10] xref: EMBL:AAI17117.1 xref: UniProtKB:Q17S10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019286 ! ADCYAP1R1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056190 name: Q1KKQ2_HUMAN def: "Protein kinase D1" [UniProtKB:Q1KKQ2] xref: EMBL:ABE96833.1 xref: UniProtKB:Q1KKQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021046 ! PRKD1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056191 name: Q1M182_HUMAN def: "HMGA2f" [UniProtKB:Q1M182] xref: EMBL:AAU43857.1 xref: UniProtKB:Q1M182 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011851 ! HMGA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056192 name: Q1M186_HUMAN def: "HMGA2d" [UniProtKB:Q1M186] xref: EMBL:AAU43853.1 xref: UniProtKB:Q1M186 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011851 ! HMGA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056193 name: Q1T7F5_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q1T7F5] xref: EMBL:BAE93188.1 xref: UniProtKB:Q1T7F5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056194 name: Q1T7F6_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q1T7F6] xref: EMBL:BAE93187.1 xref: UniProtKB:Q1T7F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056195 name: Q1W5D8_HUMAN def: "Rab6A variant 3" [UniProtKB:Q1W5D8] xref: EMBL:ABD93919.1 xref: UniProtKB:Q1W5D8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056196 name: Q1WD23_HUMAN def: "MLL/AF6 fusion protein" [UniProtKB:Q1WD23] xref: EMBL:ABD93582.1 xref: UniProtKB:Q1WD23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021109 ! MLL/AF6 fusion_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056197 name: Q24JR0_HUMAN def: "ZFY protein" [UniProtKB:Q24JR0] xref: EMBL:AAI14527.1 xref: UniProtKB:Q24JR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020601 ! ZFY_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056198 name: Q27Q50_HUMAN xref: UniProtKB:Q27Q50 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056199 name: MICB_HUMAN def: "MHC class I polypeptide-related sequence B precursor" [UniProtKB:Q29980] synonym: "MIC-B" EXACT [UniProtKB:Q29980] xref: EMBL:AAB42011.1 xref: EMBL:AAB51802.1 xref: EMBL:AAB71642.1 xref: EMBL:AAB71643.1 xref: EMBL:AAB71644.1 xref: EMBL:AAB71645.1 xref: EMBL:AAB71646.1 xref: EMBL:AAB71647.1 xref: EMBL:AAC39846.1 xref: EMBL:AAC39847.1 xref: EMBL:AAC39848.1 xref: EMBL:AAC39849.1 xref: EMBL:AAC39850.1 xref: EMBL:AAC39851.1 xref: EMBL:ABO16470.1 xref: EMBL:ABO16471.1 xref: EMBL:BAA23476.1 xref: EMBL:BAA23477.1 xref: EMBL:BAA23478.1 xref: EMBL:BAA23479.1 xref: EMBL:BAA23480.1 xref: EMBL:BAA23481.1 xref: EMBL:BAA23482.1 xref: EMBL:BAA23483.1 xref: EMBL:BAA23484.1 xref: EMBL:BAB63307.1 xref: EMBL:CAA62823.1 xref: EMBL:CAB72097.1 xref: EMBL:CAB72098.1 xref: EMBL:CAB72101.1 xref: EMBL:CAD91554.1 xref: EMBL:CAE54932.1 xref: EMBL:CAE54933.1 xref: EMBL:CAE54934.1 xref: EMBL:CAE54935.1 xref: EMBL:CAE54936.1 xref: EMBL:CAE54937.1 xref: EMBL:CAE54938.1 xref: EMBL:CAE54939.1 xref: EMBL:CAE54940.1 xref: EMBL:CAE54941.1 xref: EMBL:CAE54942.1 xref: EMBL:CAE54943.1 xref: EMBL:CAE54944.1 xref: EMBL:CAE54945.1 xref: EMBL:CAE54946.1 xref: EMBL:CAE54947.1 xref: EMBL:CAE54948.1 xref: EMBL:CAE54949.1 xref: EMBL:CAE54955.1 xref: EMBL:CAE54956.1 xref: EMBL:CAE54957.1 xref: EMBL:CAI17555.1 xref: EMBL:CAI18082.1 xref: EMBL:CAI18629.1 xref: EMBL:CAI18747.1 xref: EMBL:CAQ07170.1 xref: EMBL:CAQ09224.1 xref: EMBL:CAQ10628.1 xref: UniProtKB:A6NP85 xref: UniProtKB:B0UZ10 xref: UniProtKB:O14499 xref: UniProtKB:O14500 xref: UniProtKB:O19798 xref: UniProtKB:O19799 xref: UniProtKB:O19800 xref: UniProtKB:O19801 xref: UniProtKB:O19802 xref: UniProtKB:O19803 xref: UniProtKB:O78099 xref: UniProtKB:O78100 xref: UniProtKB:O78101 xref: UniProtKB:O78102 xref: UniProtKB:O78103 xref: UniProtKB:O78104 xref: UniProtKB:P79525 xref: UniProtKB:P79541 xref: UniProtKB:Q29980 xref: UniProtKB:Q5GR31 xref: UniProtKB:Q5GR37 xref: UniProtKB:Q5GR41 xref: UniProtKB:Q5GR42 xref: UniProtKB:Q5GR43 xref: UniProtKB:Q5GR44 xref: UniProtKB:Q5GR46 xref: UniProtKB:Q5GR48 xref: UniProtKB:Q5RIY6 xref: UniProtKB:Q5SSK1 xref: UniProtKB:Q5ST25 xref: UniProtKB:Q7JK51 xref: UniProtKB:Q7YQ89 xref: UniProtKB:Q9MY18 xref: UniProtKB:Q9MY19 xref: UniProtKB:Q9MY20 xref: UniProtKB:Q9UBH4 xref: UniProtKB:Q9UBZ8 xref: UniProtKB:Q9UEJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013665 ! MICB_human relationship: has_function CCO:F0006242 ! natural killer cell lectin-like receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001669 ! MHC class I protein complex relationship: participates_in CCO:P0000547 ! immune response-activating cell surface receptor signaling pathway [Term] id: CCO:B0056200 name: MICA_HUMAN def: "MHC class I polypeptide-related sequence A precursor" [UniProtKB:Q29983] synonym: "MIC-A" EXACT [UniProtKB:Q29983] xref: EMBL:AAA21718.1 xref: EMBL:AAB41060.1 xref: EMBL:AAB41061.1 xref: EMBL:AAB41062.1 xref: EMBL:AAB41063.1 xref: EMBL:AAB41064.1 xref: EMBL:AAB41065.1 xref: EMBL:AAB41066.1 xref: EMBL:AAB41067.1 xref: EMBL:AAB41068.1 xref: EMBL:AAB41069.1 xref: EMBL:AAB41070.1 xref: EMBL:AAB41071.1 xref: EMBL:AAB41072.1 xref: EMBL:AAB41073.1 xref: EMBL:AAB41074.1 xref: EMBL:AAB41075.1 xref: EMBL:AAC28941.1 xref: EMBL:AAC28942.1 xref: EMBL:AAC28943.1 xref: EMBL:AAC28944.1 xref: EMBL:AAC28945.1 xref: EMBL:AAD01473.1 xref: EMBL:AAD01474.1 xref: EMBL:AAD01475.1 xref: EMBL:AAD01476.1 xref: EMBL:AAD01477.1 xref: EMBL:AAD01478.1 xref: EMBL:AAD01479.1 xref: EMBL:AAD01480.1 xref: EMBL:AAD01481.1 xref: EMBL:AAD01482.1 xref: EMBL:AAD01483.1 xref: EMBL:AAD01484.1 xref: EMBL:AAD01485.1 xref: EMBL:AAD01486.1 xref: EMBL:AAD01487.1 xref: EMBL:AAD01488.1 xref: EMBL:AAD01489.1 xref: EMBL:AAD01490.1 xref: EMBL:AAD01491.1 xref: EMBL:AAD01492.1 xref: EMBL:AAD19598.1 xref: EMBL:AAD19599.1 xref: EMBL:AAD19600.1 xref: EMBL:AAD19601.1 xref: EMBL:AAD19602.1 xref: EMBL:AAD19603.1 xref: EMBL:AAD19604.1 xref: EMBL:AAD19605.1 xref: EMBL:AAD27006.1 xref: EMBL:AAD27007.1 xref: EMBL:AAD27008.1 xref: EMBL:AAD27009.1 xref: EMBL:AAD52060.1 xref: EMBL:AAD52061.1 xref: EMBL:AAD52062.1 xref: EMBL:AAD52063.1 xref: EMBL:AAD52064.1 xref: EMBL:AAD52065.1 xref: EMBL:AAD52066.1 xref: EMBL:AAD52067.1 xref: EMBL:AAD52068.1 xref: EMBL:AAD52069.1 xref: EMBL:AAD52070.1 xref: EMBL:AAD52071.1 xref: EMBL:AAD52072.1 xref: EMBL:AAH16929.1 xref: EMBL:AAK17997.1 xref: EMBL:AAK18281.1 xref: EMBL:AAK19622.1 xref: EMBL:AAK19623.1 xref: EMBL:AAK20897.1 xref: EMBL:AAK20898.1 xref: EMBL:AAK20899.1 xref: EMBL:AAK25770.1 xref: EMBL:AAK25771.1 xref: EMBL:AAK26323.1 xref: EMBL:AAK26324.1 xref: EMBL:AAK27364.1 xref: EMBL:AAK51140.1 xref: EMBL:AAK58536.1 xref: EMBL:AAK58537.1 xref: EMBL:AAK58538.1 xref: EMBL:AAL13171.1 xref: EMBL:AAM34484.1 xref: EMBL:AAU95382.1 xref: EMBL:AAV39504.1 xref: EMBL:ABX54884.1 xref: EMBL:ABX60404.1 xref: EMBL:BAA29034.1 xref: EMBL:CAA63427.1 xref: EMBL:CAA76393.1 xref: EMBL:CAA76394.1 xref: EMBL:CAA76395.1 xref: EMBL:CAA76396.1 xref: EMBL:CAA76397.1 xref: EMBL:CAA76398.1 xref: EMBL:CAA76399.1 xref: EMBL:CAA76400.1 xref: EMBL:CAA76401.1 xref: EMBL:CAA76402.1 xref: EMBL:CAA76403.1 xref: EMBL:CAA77029.1 xref: EMBL:CAA77030.1 xref: EMBL:CAA77031.1 xref: EMBL:CAB71317.1 xref: EMBL:CAC14280.1 xref: EMBL:CAC14281.1 xref: EMBL:CAC14282.1 xref: EMBL:CAC14283.1 xref: EMBL:CAC14284.1 xref: EMBL:CAC14285.1 xref: EMBL:CAC14286.1 xref: EMBL:CAC14287.1 xref: EMBL:CAC14288.1 xref: EMBL:CAC15380.1 xref: EMBL:CAC15381.1 xref: EMBL:CAC15382.1 xref: EMBL:CAC15383.1 xref: EMBL:CAC16142.1 xref: EMBL:CAC16143.1 xref: EMBL:CAC27561.1 xref: EMBL:CAC88121.1 xref: EMBL:CAD91415.1 xref: EMBL:CAE45581.1 xref: EMBL:CAE45582.2 xref: EMBL:CAI41907.1 xref: EMBL:CAP12057.1 xref: EMBL:CAQ11015.1 xref: EMBL:CAQ16171.1 xref: UniProtKB:A8KQR0 xref: UniProtKB:A9LRW5 xref: UniProtKB:A9QVE0 xref: UniProtKB:B1VJF1 xref: UniProtKB:O60917 xref: UniProtKB:O60918 xref: UniProtKB:O60919 xref: UniProtKB:O60920 xref: UniProtKB:O60933 xref: UniProtKB:O77956 xref: UniProtKB:O78150 xref: UniProtKB:O78151 xref: UniProtKB:O78152 xref: UniProtKB:O78153 xref: UniProtKB:O97987 xref: UniProtKB:O97988 xref: UniProtKB:O97989 xref: UniProtKB:O97990 xref: UniProtKB:O97991 xref: UniProtKB:O97992 xref: UniProtKB:O97993 xref: UniProtKB:O97994 xref: UniProtKB:O97995 xref: UniProtKB:O98234 xref: UniProtKB:O98235 xref: UniProtKB:O98236 xref: UniProtKB:O98237 xref: UniProtKB:O98238 xref: UniProtKB:P79506 xref: UniProtKB:P79507 xref: UniProtKB:P79508 xref: UniProtKB:P79509 xref: UniProtKB:P79510 xref: UniProtKB:P79511 xref: UniProtKB:P79512 xref: UniProtKB:P79513 xref: UniProtKB:P79514 xref: UniProtKB:P79515 xref: UniProtKB:P79516 xref: UniProtKB:P79517 xref: UniProtKB:P79518 xref: UniProtKB:P79519 xref: UniProtKB:P79520 xref: UniProtKB:P79521 xref: UniProtKB:Q29983 xref: UniProtKB:Q5C9P8 xref: UniProtKB:Q5XM81 xref: UniProtKB:Q70I48 xref: UniProtKB:Q70I49 xref: UniProtKB:Q7JFH9 xref: UniProtKB:Q7JFI0 xref: UniProtKB:Q7JFI1 xref: UniProtKB:Q7JFI2 xref: UniProtKB:Q7YQ98 xref: UniProtKB:Q861I1 xref: UniProtKB:Q95464 xref: UniProtKB:Q95HA2 xref: UniProtKB:Q95HD6 xref: UniProtKB:Q95HN4 xref: UniProtKB:Q95HN5 xref: UniProtKB:Q95HN6 xref: UniProtKB:Q95IB2 xref: UniProtKB:Q95IY7 xref: UniProtKB:Q99692 xref: UniProtKB:Q9BCR3 xref: UniProtKB:Q9BCR4 xref: UniProtKB:Q9BCR5 xref: UniProtKB:Q9BCR6 xref: UniProtKB:Q9BCR7 xref: UniProtKB:Q9BCR8 xref: UniProtKB:Q9BCR9 xref: UniProtKB:Q9BCS0 xref: UniProtKB:Q9BCS1 xref: UniProtKB:Q9BCS2 xref: UniProtKB:Q9BCS3 xref: UniProtKB:Q9BCS4 xref: UniProtKB:Q9BD20 xref: UniProtKB:Q9GIZ1 xref: UniProtKB:Q9GIZ2 xref: UniProtKB:Q9GIZ3 xref: UniProtKB:Q9GIZ4 xref: UniProtKB:Q9GIZ5 xref: UniProtKB:Q9GIZ6 xref: UniProtKB:Q9GJ01 xref: UniProtKB:Q9GJ02 xref: UniProtKB:Q9GJ03 xref: UniProtKB:Q9GJ04 xref: UniProtKB:Q9GJ05 xref: UniProtKB:Q9GJ06 xref: UniProtKB:Q9GJ07 xref: UniProtKB:Q9GJ08 xref: UniProtKB:Q9GJ09 xref: UniProtKB:Q9MY21 xref: UniProtKB:Q9TQ86 xref: UniProtKB:Q9TQ87 xref: UniProtKB:Q9TQ88 xref: UniProtKB:Q9TQ89 xref: UniProtKB:Q9TQ92 xref: UniProtKB:Q9TQ93 xref: UniProtKB:Q9TQ94 xref: UniProtKB:Q9TQ95 xref: UniProtKB:Q9TQ96 xref: UniProtKB:Q9TQ97 xref: UniProtKB:Q9TQ98 xref: UniProtKB:Q9TQ99 xref: UniProtKB:Q9TQA0 xref: UniProtKB:Q9TQA1 xref: UniProtKB:Q9TQA2 xref: UniProtKB:Q9TQA3 xref: UniProtKB:Q9TQA4 xref: UniProtKB:Q9TQI9 xref: UniProtKB:Q9TQJ0 xref: UniProtKB:Q9TQJ1 xref: UniProtKB:Q9TQJ9 xref: UniProtKB:Q9TQK0 xref: UniProtKB:Q9TQK1 xref: UniProtKB:Q9TQK2 xref: UniProtKB:Q9TQK8 xref: UniProtKB:Q9TQK9 xref: UniProtKB:Q9TQL0 xref: UniProtKB:Q9TQL1 xref: UniProtKB:Q9TQL2 xref: UniProtKB:Q9TQL3 xref: UniProtKB:Q9TQL4 xref: UniProtKB:Q9UE04 xref: UniProtKB:Q9UE05 xref: UniProtKB:Q9UE06 xref: UniProtKB:Q9UE11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008396 ! MICA_human relationship: has_function CCO:F0004595 ! beta-2-microglobulin binding relationship: has_function CCO:F0006242 ! natural killer cell lectin-like receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001669 ! MHC class I protein complex relationship: participates_in CCO:P0000534 ! stimulatory C-type lectin receptor signaling pathway [Term] id: CCO:B0056201 name: Q2HPP7_HUMAN def: "Autogenous vein graft remodeling associated protein 4" [UniProtKB:Q2HPP7] xref: EMBL:CAJ77183.1 xref: UniProtKB:Q2HPP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021111 ! AVGR4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056202 name: RFX7_HUMAN def: "DNA-binding protein RFX7" [UniProtKB:Q2KHR2] synonym: "Regulatory factor X 7" EXACT [UniProtKB:Q2KHR2] synonym: "Regulatory factor X domain-containing protein 2" EXACT [UniProtKB:Q2KHR2] xref: EMBL:AAI12937.1 xref: EMBL:BAB14381.1 xref: EMBL:BAB14988.1 xref: EMBL:BAC86441.1 xref: EMBL:BAC87248.1 xref: EMBL:CAD38972.1 xref: UniProtKB:Q2KHR2 xref: UniProtKB:Q6ZRR1 xref: UniProtKB:Q6ZTY6 xref: UniProtKB:Q8N3J0 xref: UniProtKB:Q9H7A9 xref: UniProtKB:Q9H956 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022566 ! RFX7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069902 ! RFX7_HUMAN-Phosphoserine1081 [Term] id: CCO:B0056203 name: Q2KJ05_HUMAN def: "Zinc finger E-box binding homeobox 1" [UniProtKB:Q2KJ05] synonym: "Putative uncharacterized protein ZEB1" EXACT [UniProtKB:Q2KJ05] xref: EMBL:AAI12393.1 xref: UniProtKB:Q2KJ05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020576 ! ZEB1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056204 name: Q2M1H4_HUMAN def: "Diacylglycerol kinase, gamma 90kDa" [UniProtKB:Q2M1H4] xref: EMBL:AAI12364.1 xref: UniProtKB:Q2M1H4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017568 ! DGKG_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056205 name: ZN423_HUMAN def: "Zinc finger protein 423" [UniProtKB:Q2M1K9] synonym: "hOAZ" EXACT [UniProtKB:Q2M1K9] synonym: "Olf1/EBF-associated zinc finger protein" EXACT [UniProtKB:Q2M1K9] synonym: "Smad- and Olf-interacting zinc finger protein" EXACT [UniProtKB:Q2M1K9] xref: EMBL:AAF28354.1 xref: EMBL:AAI12316.1 xref: EMBL:AAI12318.1 xref: EMBL:BAA34480.2 xref: UniProtKB:O94860 xref: UniProtKB:Q2M1K9 xref: UniProtKB:Q76N04 xref: UniProtKB:Q9NZ13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020743 ! ZNF423_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0072122 ! ZN423_HUMAN-Phosphoserine599 relationship: transforms_into CCO:B0072123 ! ZN423_HUMAN-Phosphoserine604 relationship: transforms_into CCO:B0072124 ! ZN423_HUMAN-Phosphoserine608 [Term] id: CCO:B0056206 name: ISX_HUMAN def: "Intestine-specific homeobox" [UniProtKB:Q2M1V0] synonym: "RAX-like homeobox" EXACT [UniProtKB:Q2M1V0] xref: EMBL:AAI12213.1 xref: EMBL:AAI13634.1 xref: EMBL:CAH18225.1 xref: EMBL:CAI18752.1 xref: EMBL:CAI19818.1 xref: UniProtKB:Q2M1V0 xref: UniProtKB:Q68DJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018329 ! ISX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056207 name: CDGAP_HUMAN def: "Cdc42 GTPase-activating protein" [UniProtKB:Q2M1Z3] xref: EMBL:AAI12164.1 xref: EMBL:AAI12166.1 xref: EMBL:BAA86518.1 xref: UniProtKB:Q2M1Z3 xref: UniProtKB:Q9ULL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017319 ! CDGAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064227 ! CDGAP_HUMAN-Phosphothreonine789 relationship: transforms_into CCO:B0064228 ! CDGAP_HUMAN-Phosphoserine1105 relationship: transforms_into CCO:B0064229 ! CDGAP_HUMAN-Phosphoserine1106 [Term] id: CCO:B0056208 name: ZN630_HUMAN def: "Zinc finger protein 630" [UniProtKB:Q2M218] xref: EMBL:AAI12140.2 xref: EMBL:CAI42941.2 xref: EMBL:EAW59337.1 xref: UniProtKB:Q2M218 xref: UniProtKB:Q5H8Z5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020867 ! ZNF630_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056209 name: Q2M269_HUMAN xref: UniProtKB:Q2M269 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056210 name: TBC28_HUMAN def: "TBC1 domain family member 28" [UniProtKB:Q2M2D7] xref: EMBL:AAI12013.1 xref: EMBL:AAI12017.1 xref: UniProtKB:Q2M2D7 xref: UniProtKB:Q2M2E1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020169 ! TBC1D28_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056211 name: Q2M3M4_HUMAN def: "OR13A1 protein (HCG1647786)" [UniProtKB:Q2M3M4] xref: EMBL:AAI04854.1 xref: EMBL:AAI04856.1 xref: EMBL:EAW86641.1 xref: UniProtKB:Q2M3M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021112 ! OR13A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056212 name: Q2M3U3_HUMAN def: "Interleukin 1 receptor accessory protein-like 2" [UniProtKB:Q2M3U3] synonym: "cDNA FLJ76776, highly similar to Homo sapiens interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), mRNA" EXACT [UniProtKB:Q2M3U3] xref: EMBL:AAI04785.1 xref: EMBL:AAI04787.1 xref: EMBL:BAF82885.1 xref: EMBL:CAI41969.1 xref: EMBL:CAI41981.1 xref: EMBL:CAI41987.1 xref: EMBL:CAI41989.1 xref: EMBL:CAI41995.1 xref: EMBL:CAI42001.1 xref: EMBL:CAI42006.1 xref: EMBL:CAI42894.1 xref: UniProtKB:Q2M3U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018317 ! IL1RAPL2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001257 ! interleukin-1, Type II, blocking receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056213 name: ZN181_HUMAN def: "Zinc finger protein 181" [UniProtKB:Q2M3W8] synonym: "HHZ181" EXACT [UniProtKB:Q2M3W8] xref: EMBL:AAH43228.1 xref: EMBL:AAI04760.1 xref: UniProtKB:Q2M3W8 xref: UniProtKB:Q49A75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020642 ! ZNF181_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056214 name: ZN674_HUMAN def: "Zinc finger protein 674" [UniProtKB:Q2M3X9] xref: EMBL:AAY40800.1 xref: UniProtKB:Q2M3X9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020890 ! ZNF674_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056215 name: SPRE3_HUMAN def: "Sprouty-related, EVH1 domain-containing protein 3" [UniProtKB:Q2MJR0] synonym: "Spred-3" EXACT [UniProtKB:Q2MJR0] xref: EMBL:ABC54712.1 xref: UniProtKB:Q2MJR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020021 ! SPRED3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0056216 name: Q2MZ38_HUMAN def: "Type II gonadotropin-releasing hormone receptor" [UniProtKB:Q2MZ38] synonym: "Putative uncharacterized protein GNRHR2" EXACT [UniProtKB:Q2MZ38] synonym: "Type II gonadotropin-releasing hormone receptor splice variant" EXACT [UniProtKB:Q2MZ38] xref: EMBL:ABB82942.1 xref: EMBL:BAF35581.1 xref: UniProtKB:A6NNH5 xref: UniProtKB:Q2MZ38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017948 ! GNRHR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056217 name: Q2NKL1_HUMAN def: "NR3C2 protein" [UniProtKB:Q2NKL1] xref: EMBL:AAI11759.1 xref: UniProtKB:Q2NKL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018592 ! NR3C2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056218 name: SGSM1_HUMAN def: "Small G protein signaling modulator 1" [UniProtKB:Q2NKQ1] synonym: "RUN and TBC1 domain-containing protein 2" EXACT [UniProtKB:Q2NKQ1] xref: EMBL:AAI11699.1 xref: EMBL:BAB85527.1 xref: EMBL:BAF63511.1 xref: EMBL:CAQ08970.1 xref: EMBL:CAQ08971.1 xref: UniProtKB:A5LGW1 xref: UniProtKB:B0QYW0 xref: UniProtKB:B0QYW1 xref: UniProtKB:Q2NKQ1 xref: UniProtKB:Q5TFL3 xref: UniProtKB:Q8TF60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019882 ! SGSM1_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056219 name: Q2NL85_HUMAN def: "G protein-coupled receptor, family C, group 5, member C" [UniProtKB:Q2NL85] synonym: "cDNA FLJ16084 fis, clone NT2RI2009583, highly similar to G-protein coupled receptor family C group 5 member C" EXACT [UniProtKB:Q2NL85] xref: EMBL:AAI10849.1 xref: EMBL:AAI25081.1 xref: EMBL:AAI25082.1 xref: EMBL:BAG54752.1 xref: UniProtKB:Q2NL85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017997 ! GPRC5C_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056220 name: Q2PJS5_HUMAN def: "PAX7 transcriptional factor isoform B" [UniProtKB:Q2PJS5] xref: EMBL:ABC48797.1 xref: UniProtKB:Q2PJS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021113 ! PAX7B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056221 name: Q2PNZ1_HUMAN def: "G protein-coupled receptor 111" [UniProtKB:Q2PNZ1] xref: EMBL:ABC41928.1 xref: UniProtKB:Q2PNZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017955 ! GPR111_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056222 name: AS250_HUMAN def: "250 kDa substrate of Akt" [UniProtKB:Q2PPJ7] synonym: "AS250" EXACT [UniProtKB:Q2PPJ7] xref: EMBL:AAH13749.1 xref: EMBL:ABC33805.1 xref: EMBL:BAA86586.1 xref: EMBL:BAB14290.1 xref: EMBL:CAC27348.1 xref: EMBL:CAI12810.1 xref: EMBL:CAI39939.1 xref: EMBL:CAI39940.1 xref: EMBL:CAI40814.1 xref: EMBL:CAI40815.1 xref: EMBL:CAI95625.1 xref: EMBL:CAI95626.1 xref: EMBL:CAI95627.1 xref: UniProtKB:Q2PPJ7 xref: UniProtKB:Q4VXU6 xref: UniProtKB:Q5JUA3 xref: UniProtKB:Q5JUA4 xref: UniProtKB:Q5T9K3 xref: UniProtKB:Q96CX9 xref: UniProtKB:Q9BQT7 xref: UniProtKB:Q9H9D9 xref: UniProtKB:Q9ULE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017055 ! C20orf74_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0063618 ! AS250_HUMAN-Phosphoserine373 relationship: transforms_into CCO:B0063619 ! AS250_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0063620 ! AS250_HUMAN-Phosphoserine379 relationship: transforms_into CCO:B0063621 ! AS250_HUMAN-Phosphoserine486 relationship: transforms_into CCO:B0063622 ! AS250_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0063623 ! AS250_HUMAN-Phosphothreonine715 relationship: transforms_into CCO:B0063624 ! AS250_HUMAN-Phosphoserine820 relationship: transforms_into CCO:B0063625 ! AS250_HUMAN-Phosphoserine821 [Term] id: CCO:B0056223 name: ZXDC_HUMAN def: "Zinc finger protein ZXDC" [UniProtKB:Q2QGD7] synonym: "ZXD-like zinc finger protein" EXACT [UniProtKB:Q2QGD7] xref: EMBL:AAH02940.2 xref: EMBL:AAH12729.2 xref: EMBL:AAX23974.1 xref: EMBL:AAZ30918.1 xref: EMBL:BAC03805.1 xref: UniProtKB:Q2QGD7 xref: UniProtKB:Q7L3L1 xref: UniProtKB:Q8NAU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021012 ! ZXDC_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056224 name: Q2T9G7_HUMAN def: "ZNF304 protein" [UniProtKB:Q2T9G7] xref: EMBL:AAI11533.1 xref: UniProtKB:Q2T9G7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020698 ! ZNF304_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056225 name: Q2TAI4_HUMAN def: "ASB3 protein" [UniProtKB:Q2TAI4] xref: EMBL:AAI10916.1 xref: UniProtKB:Q2TAI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017067 ! ASB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056226 name: VWC2_HUMAN def: "Brorin precursor" [UniProtKB:Q2TAL6] synonym: "Brain-specific chordin-like protein" EXACT [UniProtKB:Q2TAL6] synonym: "von Willebrand factor C domain-containing protein 2" EXACT [UniProtKB:Q2TAL6] xref: EMBL:AAI10858.1 xref: EMBL:AAQ88759.1 xref: EMBL:BAF51551.1 xref: EMBL:EAL23904.1 xref: EMBL:EAW60985.1 xref: UniProtKB:Q2TAL6 xref: UniProtKB:Q6UXE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020468 ! VWC2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway relationship: participates_in CCO:P0002480 ! positive regulation of neuron differentiation [Term] id: CCO:B0056227 name: Q2TAM5_HUMAN def: "RELA protein" [UniProtKB:Q2TAM5] xref: EMBL:AAI10831.1 xref: UniProtKB:Q2TAM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005765 ! RELA_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056228 name: Z705C_HUMAN def: "Zinc finger protein 705C" [UniProtKB:Q2TAN0] xref: EMBL:AAI10824.1 xref: UniProtKB:Q2TAN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020535 ! ZNF705C_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056229 name: ZN800_HUMAN def: "Zinc finger protein 800" [UniProtKB:Q2TB10] xref: EMBL:AAG17274.1 xref: EMBL:AAI10624.1 xref: EMBL:AAI10625.1 xref: EMBL:EAW83626.1 xref: UniProtKB:Q2TB10 xref: UniProtKB:Q9HBN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020948 ! ZNF800_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072247 ! ZN800_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0072248 ! ZN800_HUMAN-Phosphothreonine319 relationship: transforms_into CCO:B0072249 ! ZN800_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0072250 ! ZN800_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0072251 ! ZN800_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0072252 ! ZN800_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0072253 ! ZN800_HUMAN-Phosphoserine457 relationship: transforms_into CCO:B0072254 ! ZN800_HUMAN-Phosphoserine462 [Term] id: CCO:B0056230 name: Q2TB39_HUMAN def: "TCF3 protein" [UniProtKB:Q2TB39] xref: EMBL:AAI10581.1 xref: UniProtKB:Q2TB39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005771 ! TCF3_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056231 name: Q2TBE4_HUMAN def: "PLXNB2 protein" [UniProtKB:Q2TBE4] xref: EMBL:AAI10367.1 xref: UniProtKB:Q2TBE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005341 ! PLXNB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056232 name: Q2TU37_HUMAN def: "PIG51" [UniProtKB:Q2TU37] xref: EMBL:AAT08177.1 xref: UniProtKB:Q2TU37 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056233 name: Q2V6Q1_HUMAN def: "Centaurin alpha 2" [UniProtKB:Q2V6Q1] xref: EMBL:ABB90599.1 xref: UniProtKB:Q2V6Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017329 ! CENTA2_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0056234 name: CORL2_HUMAN def: "Ladybird homeobox corepressor 1-like protein" [UniProtKB:Q2VWA4] synonym: "Functional Smad-suppressing element on chromosome 18" EXACT [UniProtKB:Q2VWA4] synonym: "Fussel-18" EXACT [UniProtKB:Q2VWA4] synonym: "LBX1 corepressor 1-like protein" EXACT [UniProtKB:Q2VWA4] xref: EMBL:AAV74189.1 xref: UniProtKB:Q2VWA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017436 ! CORL2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056235 name: ZN284_HUMAN def: "Zinc finger protein 284" [UniProtKB:Q2VY69] xref: EMBL:AAO45838.1 xref: EMBL:AAS13443.1 xref: UniProtKB:Q2VY69 xref: UniProtKB:Q86WM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020694 ! ZNF284_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056236 name: Q2YD93_HUMAN def: "BAK1 protein" [UniProtKB:Q2YD93] synonym: "BCL2-antagonist/killer 1, isoform CRA_a" EXACT [UniProtKB:Q2YD93] xref: EMBL:AAI10338.1 xref: EMBL:EAX03740.1 xref: UniProtKB:Q2YD93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004135 ! BAK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056237 name: ZN699_HUMAN def: "Zinc finger protein 699" [UniProtKB:Q32M78] synonym: "Hangover homolog" EXACT [UniProtKB:Q32M78] xref: EMBL:AAI09268.1 xref: EMBL:AAI09269.1 xref: EMBL:BAC04552.1 xref: UniProtKB:Q32M78 xref: UniProtKB:Q8N9A1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020905 ! ZNF699_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056238 name: Q32MC2_HUMAN def: "Jerky homolog-like (Mouse)" [UniProtKB:Q32MC2] xref: EMBL:AAI09203.1 xref: EMBL:EAW66986.1 xref: UniProtKB:Q32MC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021114 ! JRKL_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056239 name: Q32MI9_HUMAN xref: UniProtKB:Q32MI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056240 name: P3H1_HUMAN def: "Prolyl 3-hydroxylase 1 precursor" [UniProtKB:Q32P28] synonym: "EC 1.14.11.7" EXACT [UniProtKB:Q32P28] synonym: "Growth suppressor 1" EXACT [UniProtKB:Q32P28] synonym: "Leprecan-1" EXACT [UniProtKB:Q32P28] synonym: "Leucine- and proline-enriched proteoglycan 1" EXACT [UniProtKB:Q32P28] xref: EMBL:AAG31018.1 xref: EMBL:AAG31019.1 xref: EMBL:AAH15309.2 xref: EMBL:AAI08312.1 xref: EMBL:AAP35688.1 xref: EMBL:BAB15256.1 xref: EMBL:BAB55264.1 xref: EMBL:BAB55291.1 xref: EMBL:BAB55305.1 xref: EMBL:BAC11608.1 xref: UniProtKB:Q32P28 xref: UniProtKB:Q7KZR4 xref: UniProtKB:Q96BR8 xref: UniProtKB:Q96SK8 xref: UniProtKB:Q96SL5 xref: UniProtKB:Q96SN3 xref: UniProtKB:Q9H6K3 xref: UniProtKB:Q9HC86 xref: UniProtKB:Q9HC87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019276 ! LEPRE1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors relationship: has_function CCO:F0004174 ! procollagen-proline 3-dioxygenase activity relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0056241 name: OR4FL_HUMAN def: "Putative olfactory receptor GPCRLTM7" [UniProtKB:Q32VQ0] xref: EMBL:AAY34251.1 xref: UniProtKB:Q32VQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056242 name: RFX4_HUMAN def: "Transcription factor RFX4" [UniProtKB:Q33E94] synonym: "Regulatory factor X 4" EXACT [UniProtKB:Q33E94] synonym: "Testis development protein NYD-SP10" EXACT [UniProtKB:Q33E94] xref: EMBL:AAH28582.1 xref: EMBL:AAH30644.1 xref: EMBL:AAK17191.1 xref: EMBL:AAM52484.1 xref: EMBL:BAB59001.1 xref: EMBL:BAC11288.1 xref: EMBL:BAE48231.1 xref: EMBL:BAE48232.1 xref: EMBL:BAE48237.1 xref: EMBL:BAE48238.1 xref: EMBL:CAD38777.1 xref: EMBL:EAW97783.1 xref: EMBL:EAW97784.1 xref: UniProtKB:Q33DW6 xref: UniProtKB:Q33DW7 xref: UniProtKB:Q33E94 xref: UniProtKB:Q33E95 xref: UniProtKB:Q6YM53 xref: UniProtKB:Q8MHQ1 xref: UniProtKB:Q8NC78 xref: UniProtKB:Q8NDF9 xref: UniProtKB:Q8SNA1 xref: UniProtKB:Q96S80 xref: UniProtKB:Q9BXI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019686 ! RFX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056243 name: LRRK1_HUMAN def: "Leucine-rich repeat serine/threonine-protein kinase 1" [UniProtKB:Q38SD2] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q38SD2] xref: EMBL:AAH66655.1 xref: EMBL:AAH68080.1 xref: EMBL:AAY67799.1 xref: EMBL:BAB15547.1 xref: EMBL:BAB47419.1 xref: EMBL:BAC85125.1 xref: EMBL:BAC85472.1 xref: UniProtKB:Q38SD2 xref: UniProtKB:Q6NVH5 xref: UniProtKB:Q6NYC0 xref: UniProtKB:Q6ZNL9 xref: UniProtKB:Q6ZNM9 xref: UniProtKB:Q96JN5 xref: UniProtKB:Q9H5S3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018522 ! LRRK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056244 name: Q3B7J8_HUMAN def: "ZNF250 protein" [UniProtKB:Q3B7J8] xref: EMBL:AAI07580.1 xref: UniProtKB:Q3B7J8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020678 ! ZNF250_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056245 name: EDRF1_HUMAN def: "Erythroid differentiation-related factor 1" [UniProtKB:Q3B7T1] xref: EMBL:AAH16903.1 xref: EMBL:AAH26172.1 xref: EMBL:AAI05930.1 xref: EMBL:AAI07480.1 xref: EMBL:CAB43273.1 xref: EMBL:CAH73214.1 xref: UniProtKB:Q3B7T1 xref: UniProtKB:Q3KR40 xref: UniProtKB:Q4G190 xref: UniProtKB:Q5VZQ4 xref: UniProtKB:Q8IZ74 xref: UniProtKB:Q9Y3W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017660 ! EDRF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056246 name: PROX2_HUMAN def: "Prospero homeobox protein 2" [UniProtKB:Q3B8N5] synonym: "Homeobox prospero-like protein PROX2" EXACT [UniProtKB:Q3B8N5] synonym: "PROX-2" EXACT [UniProtKB:Q3B8N5] xref: EMBL:AAI05721.1 xref: EMBL:AAI05928.1 xref: EMBL:BAC04278.1 xref: UniProtKB:Q3B8N5 xref: UniProtKB:Q8N9Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022531 ! PROX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056247 name: Q3C1V0_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q3C1V0] xref: EMBL:BAE46897.1 xref: UniProtKB:Q3C1V0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056248 name: YK037_HUMAN def: "Putative olfactory receptor-like protein ENSP00000367619" [UniProtKB:Q3C1V7] xref: EMBL:BAE46890.1 xref: UniProtKB:A6NMH2 xref: UniProtKB:Q3C1V7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056249 name: Q3KNR4_HUMAN def: "PAX4 protein" [UniProtKB:Q3KNR4] xref: EMBL:AAI07151.1 xref: UniProtKB:Q3KNR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019308 ! PAX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056250 name: ZN829_HUMAN def: "Zinc finger protein 829" [UniProtKB:Q3KNS6] xref: EMBL:AAI07132.1 xref: EMBL:AAI07133.1 xref: EMBL:BAC85471.1 xref: EMBL:CAD98083.1 xref: UniProtKB:Q3KNS6 xref: UniProtKB:Q3KNS7 xref: UniProtKB:Q6ZNN0 xref: UniProtKB:Q7Z657 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020956 ! ZNF829_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056251 name: PCGF3_HUMAN def: "Polycomb group RING finger protein 3" [UniProtKB:Q3KNV8] synonym: "RING finger protein 3A" EXACT [UniProtKB:Q3KNV8] xref: EMBL:AAI07062.1 xref: EMBL:CAA04477.1 xref: UniProtKB:O15262 xref: UniProtKB:Q3KNV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019320 ! PCGF3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056252 name: SNAI3_HUMAN def: "Zinc finger protein SNAI3" [UniProtKB:Q3KNW1] synonym: "Protein snail homolog 3" EXACT [UniProtKB:Q3KNW1] synonym: "Zinc finger protein 293" EXACT [UniProtKB:Q3KNW1] xref: EMBL:AAH41461.1 xref: EMBL:AAI07059.1 xref: EMBL:EAW66765.1 xref: UniProtKB:Q3KNW1 xref: UniProtKB:Q86SU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019961 ! SNAI3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056253 name: ZN791_HUMAN def: "Zinc finger protein 791" [UniProtKB:Q3KP31] xref: EMBL:AAI06938.1 xref: EMBL:AAI06939.1 xref: EMBL:BAC11261.1 xref: EMBL:EAW84278.1 xref: UniProtKB:Q3KP31 xref: UniProtKB:Q8NC99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020944 ! ZNF791_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056254 name: ZN792_HUMAN def: "Zinc finger protein 792" [UniProtKB:Q3KQV3] xref: EMBL:AAI01119.1 xref: EMBL:AAI01120.1 xref: EMBL:AAI01121.1 xref: EMBL:AAI06044.1 xref: EMBL:BAG65345.1 xref: UniProtKB:B4E333 xref: UniProtKB:Q3KQV3 xref: UniProtKB:Q495L1 xref: UniProtKB:Q495L3 xref: UniProtKB:Q8N932 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020945 ! ZNF792_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056255 name: Q3KQV7_HUMAN def: "SRY (Sex determining region Y)-box 13" [UniProtKB:Q3KQV7] synonym: "SRY (Sex determining region Y)-box 13, isoform CRA_b" EXACT [UniProtKB:Q3KQV7] xref: EMBL:AAI06039.1 xref: EMBL:EAW91500.1 xref: UniProtKB:Q3KQV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019990 ! SOX13_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056256 name: PKHG6_HUMAN def: "Pleckstrin homology domain-containing family G member 6" [UniProtKB:Q3KR16] synonym: "MyoGEF" EXACT [UniProtKB:Q3KR16] synonym: "Myosin-interacting guanine nucleotide exchange factor" EXACT [UniProtKB:Q3KR16] xref: EMBL:AAI04752.1 xref: EMBL:AAI05962.1 xref: EMBL:AAI09096.1 xref: EMBL:AAL55797.1 xref: EMBL:BAA91741.1 xref: EMBL:BAB14663.1 xref: EMBL:BAC04539.1 xref: EMBL:EAW88809.1 xref: UniProtKB:Q3KR16 xref: UniProtKB:Q3SWR1 xref: UniProtKB:Q8N1P1 xref: UniProtKB:Q8WYY1 xref: UniProtKB:Q9H8F4 xref: UniProtKB:Q9NVK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019418 ! PLEKHG6_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0069358 ! PKHG6_HUMAN-Phosphoserine33 [Term] id: CCO:B0056257 name: Q3KR29_HUMAN def: "WNT1 inducible signaling pathway protein 3" [UniProtKB:Q3KR29] synonym: "WNT1 inducible signaling pathway protein 3, isoform CRA_c" EXACT [UniProtKB:Q3KR29] xref: EMBL:AAI05942.1 xref: EMBL:EAW48275.1 xref: UniProtKB:Q3KR29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020477 ! WISP3_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056258 name: Q3KR30_HUMAN def: "WISP3 protein" [UniProtKB:Q3KR30] xref: EMBL:AAI05941.1 xref: UniProtKB:Q3KR30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020477 ! WISP3_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056259 name: Q3KRA7_HUMAN def: "FGA protein" [UniProtKB:Q3KRA7] xref: EMBL:AAI05804.1 xref: UniProtKB:Q3KRA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017805 ! FGA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056260 name: RHGBB_HUMAN def: "Rho GTPase-activating protein 11B" [UniProtKB:Q3KRB8] synonym: "Rho-type GTPase-activating protein 11B" EXACT [UniProtKB:Q3KRB8] xref: EMBL:AAI05789.1 xref: UniProtKB:Q3KRB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019730 ! ARHGAP11B_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056261 name: CHD9_HUMAN def: "Chromodomain-helicase-DNA-binding protein 9" [UniProtKB:Q3L8U1] synonym: "ATP-dependent helicase CHD9" EXACT [UniProtKB:Q3L8U1] synonym: "CHD-9" EXACT [UniProtKB:Q3L8U1] synonym: "Chromatin-related mesenchymal modulator" EXACT [UniProtKB:Q3L8U1] synonym: "Chromatin-remodeling factor CHROM1" EXACT [UniProtKB:Q3L8U1] synonym: "CReMM" EXACT [UniProtKB:Q3L8U1] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q3L8U1] synonym: "Kismet homolog 2" EXACT [UniProtKB:Q3L8U1] synonym: "Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein" EXACT [UniProtKB:Q3L8U1] synonym: "PPAR-alpha-interacting complex protein 320 kDa" EXACT [UniProtKB:Q3L8U1] xref: EMBL:AAF24170.1 xref: EMBL:AAQ24287.1 xref: EMBL:AAT66509.1 xref: EMBL:ABD24032.1 xref: EMBL:BAA20767.3 xref: EMBL:BAB14112.1 xref: UniProtKB:O15025 xref: UniProtKB:Q1WF12 xref: UniProtKB:Q3L8U1 xref: UniProtKB:Q6DTK9 xref: UniProtKB:Q9H9V7 xref: UniProtKB:Q9UHM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017353 ! CHD9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064341 ! CHD9_HUMAN-Phosphoserine550 relationship: transforms_into CCO:B0064342 ! CHD9_HUMAN-Phosphoserine611 relationship: transforms_into CCO:B0064343 ! CHD9_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0064344 ! CHD9_HUMAN-Phosphoserine616 relationship: transforms_into CCO:B0064345 ! CHD9_HUMAN-Phosphothreonine625 relationship: transforms_into CCO:B0064346 ! CHD9_HUMAN-Phosphotyrosine645 relationship: transforms_into CCO:B0064347 ! CHD9_HUMAN-Phosphoserine1468 relationship: transforms_into CCO:B0064348 ! CHD9_HUMAN-Phosphoserine1472 relationship: transforms_into CCO:B0064349 ! CHD9_HUMAN-Phosphothreonine2013 relationship: transforms_into CCO:B0064350 ! CHD9_HUMAN-Phosphoserine2026 relationship: transforms_into CCO:B0064351 ! CHD9_HUMAN-Phosphoserine2879 relationship: transforms_into CCO:B0064352 ! CHD9_HUMAN-Phosphoserine2883 relationship: transforms_into CCO:B0064353 ! CHD9_HUMAN-Phosphoserine2891 [Term] id: CCO:B0056262 name: TBC25_HUMAN def: "TBC1 domain family member 25" [UniProtKB:Q3MII6] xref: EMBL:AAH26050.1 xref: EMBL:AAI01818.1 xref: EMBL:AAI01820.1 xref: EMBL:AAI25089.1 xref: EMBL:AAI25090.2 xref: UniProtKB:Q08AN9 xref: UniProtKB:Q3MII4 xref: UniProtKB:Q3MII6 xref: UniProtKB:Q8TAR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020167 ! TBC1D25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071219 ! TBC25_HUMAN-Phosphoserine506 [Term] id: CCO:B0056263 name: Q3MIY3_HUMAN def: "POU class 2 homeobox 3" [UniProtKB:Q3MIY3] xref: EMBL:AAI01650.1 xref: UniProtKB:Q3MIY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005352 ! POU2F3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056264 name: Q3MJ29_HUMAN def: "Postmeiotic segregation increased 2-like 3" [UniProtKB:Q3MJ29] synonym: "Postmeiotic segregation increased 2-like 3, isoform CRA_b" EXACT [UniProtKB:Q3MJ29] xref: EMBL:AAI01599.1 xref: EMBL:EAW71766.1 xref: UniProtKB:Q3MJ29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019453 ! PMS2L3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056265 name: ZSC23_HUMAN def: "Zinc finger and SCAN domain-containing protein 23" [UniProtKB:Q3MJ62] synonym: "Zinc finger protein 390" EXACT [UniProtKB:Q3MJ62] synonym: "Zinc finger protein 453" EXACT [UniProtKB:Q3MJ62] xref: EMBL:AAI01558.1 xref: EMBL:AAI01560.1 xref: EMBL:CAC44641.1 xref: UniProtKB:Q3MJ62 xref: UniProtKB:Q96KV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021005 ! ZSCAN23_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056266 name: Q3SAH2_HUMAN def: "G-protein-coupled receptor 34 splice variant" [UniProtKB:Q3SAH2] xref: EMBL:AAZ99228.1 xref: EMBL:AAZ99229.1 xref: UniProtKB:Q3SAH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018017 ! GPR34_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056267 name: Q3SX80_HUMAN def: "BCL2-like 10 (Apoptosis facilitator)" [UniProtKB:Q3SX80] xref: EMBL:AAI04444.1 xref: UniProtKB:Q3SX80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021115 ! BCL2L10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056268 name: Q3SXL4_HUMAN def: "NPFF protein" [UniProtKB:Q3SXL4] synonym: "Neuropeptide FF-amide peptide, isoform CRA_a" EXACT [UniProtKB:Q3SXL4] xref: EMBL:AAI04235.1 xref: EMBL:AAI04236.1 xref: EMBL:EAW96721.1 xref: UniProtKB:Q3SXL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018834 ! NPFF_human relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056269 name: ZN718_HUMAN def: "Zinc finger protein 718" [UniProtKB:Q3SXZ3] xref: EMBL:AAI04027.1 xref: EMBL:AAI04028.1 xref: EMBL:AAI04029.1 xref: EMBL:AAI04030.1 xref: UniProtKB:Q3SXZ3 xref: UniProtKB:Q3SXZ4 xref: UniProtKB:Q3SXZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020917 ! ZNF718_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056270 name: SP6_HUMAN def: "Transcription factor Sp6" [UniProtKB:Q3SY56] synonym: "Krueppel-like factor 14" EXACT [UniProtKB:Q3SY56] xref: EMBL:AAI03952.1 xref: EMBL:AAI03953.1 xref: EMBL:AAI03954.1 xref: EMBL:AAI03955.1 xref: UniProtKB:Q3SY56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020005 ! SP6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056271 name: Q3SY79_HUMAN def: "Protein Wnt" [UniProtKB:Q3SY79] xref: EMBL:AAI03922.1 xref: EMBL:AAI03924.1 xref: UniProtKB:Q3SY79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020487 ! WNT3A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056272 name: EA3L1_HUMAN def: "RNA polymerase II transcription factor SIII subunit A3-like-1" [UniProtKB:Q3SY89] synonym: "EloA3-like-1" EXACT [UniProtKB:Q3SY89] synonym: "Elongin-A3-like-1" EXACT [UniProtKB:Q3SY89] synonym: "Transcription elongation factor B polypeptide 3C-like-1" EXACT [UniProtKB:Q3SY89] xref: EMBL:AAI03913.1 xref: EMBL:AAI03914.1 xref: UniProtKB:Q3MI93 xref: UniProtKB:Q3SY89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022205 ! TCEB3CL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056273 name: Q3SYD4_HUMAN def: "SSX4 protein" [UniProtKB:Q3SYD4] xref: EMBL:AAI03865.1 xref: UniProtKB:Q3SYD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020051 ! SSX4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056274 name: Q3SYD7_HUMAN def: "BRF1 protein" [UniProtKB:Q3SYD7] xref: EMBL:AAI03862.1 xref: UniProtKB:Q3SYD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015034 ! BRF1_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056275 name: Q3SYD8_HUMAN def: "BRF1 protein" [UniProtKB:Q3SYD8] xref: EMBL:AAI03861.1 xref: UniProtKB:Q3SYD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0015034 ! BRF1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056276 name: GON4L_HUMAN def: "GON-4-like protein" [UniProtKB:Q3T8J9] synonym: "GON-4 homolog" EXACT [UniProtKB:Q3T8J9] xref: EMBL:AAH36740.2 xref: EMBL:AAH64933.1 xref: EMBL:AAR01260.1 xref: EMBL:AAR01261.1 xref: EMBL:AAR01262.1 xref: EMBL:BAB13432.1 xref: EMBL:CAB66500.2 xref: EMBL:CAD97829.1 xref: EMBL:CAH10549.1 xref: EMBL:CAH69942.1 xref: EMBL:CAH69947.1 xref: EMBL:CAH71640.1 xref: UniProtKB:Q3T8J8 xref: UniProtKB:Q3T8J9 xref: UniProtKB:Q5VYZ5 xref: UniProtKB:Q5W0D5 xref: UniProtKB:Q6AWA6 xref: UniProtKB:Q6P1Q6 xref: UniProtKB:Q7Z3L3 xref: UniProtKB:Q8IY79 xref: UniProtKB:Q9BQI1 xref: UniProtKB:Q9HCG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017951 ! GON4L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066516 ! GON4L_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0066517 ! GON4L_HUMAN-Phosphoserine188 [Term] id: CCO:B0056277 name: Q3V4E3_HUMAN def: "Endocan (cDNA FLJ50870, moderately similar to Endothelial cell-specific molecule 1) precursor" [UniProtKB:Q3V4E3] xref: EMBL:BAG62324.1 xref: EMBL:CAJ13737.1 xref: UniProtKB:Q3V4E3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017729 ! ESM1_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056278 name: GRDN_HUMAN def: "Girdin" [UniProtKB:Q3V6T2] synonym: "Akt phosphorylation enhancer" EXACT [UniProtKB:Q3V6T2] synonym: "APE" EXACT [UniProtKB:Q3V6T2] synonym: "Coiled-coil domain-containing protein 88A" EXACT [UniProtKB:Q3V6T2] synonym: "G alpha-interacting vesicle-associated protein" EXACT [UniProtKB:Q3V6T2] synonym: "Girders of actin filament" EXACT [UniProtKB:Q3V6T2] synonym: "GIV" EXACT [UniProtKB:Q3V6T2] synonym: "HkRP1" EXACT [UniProtKB:Q3V6T2] synonym: "Hook-related protein 1" EXACT [UniProtKB:Q3V6T2] xref: EMBL:AAI32737.1 xref: EMBL:AAX82029.1 xref: EMBL:AAY14932.1 xref: EMBL:BAE44387.1 xref: EMBL:BAF44475.1 xref: EMBL:CAD97945.1 xref: EMBL:CAD98038.1 xref: EMBL:CAI46020.1 xref: UniProtKB:A1IGE7 xref: UniProtKB:Q3V6T2 xref: UniProtKB:Q53SF1 xref: UniProtKB:Q581G3 xref: UniProtKB:Q5HYD0 xref: UniProtKB:Q7Z339 xref: UniProtKB:Q7Z3C5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018055 ! CCDC88A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000639 ! regulation of DNA replication relationship: participates_in CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: transforms_into CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: transforms_into CCO:B0066590 ! GRDN_HUMAN-Phosphoserine1417 relationship: transforms_into CCO:B0066591 ! GRDN_HUMAN-Phosphothreonine1559 relationship: transforms_into CCO:B0066592 ! GRDN_HUMAN-Phosphothreonine1560 relationship: transforms_into CCO:B0066593 ! GRDN_HUMAN-Phosphoserine1561 relationship: transforms_into CCO:B0066594 ! GRDN_HUMAN-Phosphothreonine1673 relationship: transforms_into CCO:B0066595 ! GRDN_HUMAN-Phosphoserine1675 relationship: transforms_into CCO:B0066596 ! GRDN_HUMAN-Phosphoserine1702 relationship: transforms_into CCO:B0066597 ! GRDN_HUMAN-Phosphoserine1837 [Term] id: CCO:B0056279 name: PARF_HUMAN def: "Putative GTP-binding protein Parf" [UniProtKB:Q3YEC7] synonym: "Partner of ARF" EXACT [UniProtKB:Q3YEC7] xref: EMBL:AAH02945.2 xref: EMBL:AAH21095.2 xref: EMBL:AAH35786.1 xref: EMBL:AAZ13759.1 xref: EMBL:AAZ73768.1 xref: EMBL:BAB14408.1 xref: EMBL:BAB55213.1 xref: EMBL:CAD28504.1 xref: EMBL:CAI12685.1 xref: UniProtKB:Q3YEC7 xref: UniProtKB:Q4F968 xref: UniProtKB:Q5T5R7 xref: UniProtKB:Q8IWK1 xref: UniProtKB:Q8TCL4 xref: UniProtKB:Q8WU94 xref: UniProtKB:Q96SR8 xref: UniProtKB:Q9BU21 xref: UniProtKB:Q9H935 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019301 ! PARF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069101 ! PARF_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0069102 ! PARF_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0069103 ! PARF_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0069104 ! PARF_HUMAN-Phosphoserine454 relationship: transforms_into CCO:B0069105 ! PARF_HUMAN-Phosphoserine464 relationship: transforms_into CCO:B0069106 ! PARF_HUMAN-Phosphoserine470 relationship: transforms_into CCO:B0069107 ! PARF_HUMAN-Phosphoserine471 relationship: transforms_into CCO:B0069108 ! PARF_HUMAN-Phosphoserine577 relationship: transforms_into CCO:B0069109 ! PARF_HUMAN-Phosphoserine580 relationship: transforms_into CCO:B0069110 ! PARF_HUMAN-Phosphoserine596 relationship: transforms_into CCO:B0069111 ! PARF_HUMAN-Phosphothreonine599 relationship: transforms_into CCO:B0069112 ! PARF_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0069113 ! PARF_HUMAN-Phosphoserine641 [Term] id: CCO:B0056280 name: Q3ZAR0_HUMAN def: "GPR50 protein" [UniProtKB:Q3ZAR0] xref: EMBL:AAI03697.1 xref: EMBL:AAI05684.1 xref: UniProtKB:Q3ZAR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021116 ! GPR50_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001956 ! melatonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056281 name: Q3ZB87_HUMAN def: "SATB2 protein" [UniProtKB:Q3ZB87] xref: EMBL:AAI03493.1 xref: UniProtKB:Q3ZB87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019840 ! SATB2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056282 name: Q3ZCN2_HUMAN def: "RGL4 protein" [UniProtKB:Q3ZCN2] xref: EMBL:AAI01111.2 xref: UniProtKB:Q3ZCN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019690 ! RGL4_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056283 name: Q3ZCN8_HUMAN def: "DEP domain-containing protein 4." [UniProtKB:Q3ZCN8] xref: EMBL:AAI00929.1 xref: UniProtKB:Q3ZCN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017555 ! DEPDC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056284 name: Q3ZCR0_HUMAN def: "FAM13B1 protein" [UniProtKB:Q3ZCR0] synonym: "Chromosome 5 open reading frame 5, isoform CRA_c" EXACT [UniProtKB:Q3ZCR0] xref: EMBL:AAH48965.1 xref: EMBL:EAW62173.1 xref: UniProtKB:Q3ZCR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021117 ! FAM13B1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056285 name: Q3ZCU4_HUMAN def: "LEF1 protein" [UniProtKB:Q3ZCU4] synonym: "Lymphoid enhancer-binding factor 1, isoform CRA_d" EXACT [UniProtKB:Q3ZCU4] xref: EMBL:AAH40559.1 xref: EMBL:EAX06225.1 xref: UniProtKB:Q3ZCU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018468 ! LEF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056286 name: ZN568_HUMAN def: "Zinc finger protein 568" [UniProtKB:Q3ZCX4] xref: EMBL:AAH31218.1 xref: EMBL:BAC04064.1 xref: EMBL:CAE45810.1 xref: UniProtKB:Q3ZCX4 xref: UniProtKB:Q6N060 xref: UniProtKB:Q8NA64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020825 ! ZNF568_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056287 name: PAR15_HUMAN def: "Poly [ADP-ribose] polymerase 15" [UniProtKB:Q460N3] synonym: "B-aggressive lymphoma protein 3" EXACT [UniProtKB:Q460N3] synonym: "EC 2.4.2.30" EXACT [UniProtKB:Q460N3] synonym: "PARP-15" EXACT [UniProtKB:Q460N3] xref: EMBL:AAI01702.1 xref: EMBL:AAI01704.1 xref: EMBL:AAY64451.1 xref: EMBL:BAC05197.1 xref: UniProtKB:Q460N3 xref: UniProtKB:Q8N1K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019300 ! PARP15_human relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056288 name: PAR14_HUMAN def: "Poly [ADP-ribose] polymerase 14" [UniProtKB:Q460N5] synonym: "B aggressive lymphoma protein 2" EXACT [UniProtKB:Q460N5] synonym: "EC 2.4.2.30" EXACT [UniProtKB:Q460N5] synonym: "PARP-14" EXACT [UniProtKB:Q460N5] xref: EMBL:AAN08627.1 xref: EMBL:AAY64449.1 xref: EMBL:AAY64450.1 xref: EMBL:BAA86582.1 xref: EMBL:BAA91897.1 xref: EMBL:BAB14089.1 xref: UniProtKB:Q460N4 xref: UniProtKB:Q460N5 xref: UniProtKB:Q8J027 xref: UniProtKB:Q9H9X9 xref: UniProtKB:Q9NV60 xref: UniProtKB:Q9ULF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019299 ! PARP14_human relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056289 name: Q494T1_HUMAN def: "HAND2 protein" [UniProtKB:Q494T1] xref: EMBL:AAI01407.1 xref: UniProtKB:Q494T1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018103 ! HAND2_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056290 name: ZN404_HUMAN def: "Zinc finger protein 404" [UniProtKB:Q494X3] xref: EMBL:AAI01333.1 xref: EMBL:AAI01334.1 xref: UniProtKB:A4FU30 xref: UniProtKB:Q494X3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020732 ! ZNF404_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056291 name: Q494Z3_HUMAN def: "Paired box 3" [UniProtKB:Q494Z3] synonym: "cDNA FLJ77133, highly similar to Homo sapiens paired box gene 3 (Waardenburg syndrome 1) (PAX3), transcript variant PAX3D, mRNA" EXACT [UniProtKB:Q494Z3] synonym: "Paired box gene 3 (Waardenburg syndrome 1), isoform CRA_f" EXACT [UniProtKB:Q494Z3] xref: EMBL:AAI01302.1 xref: EMBL:BAF83967.1 xref: EMBL:EAW70794.1 xref: UniProtKB:Q494Z3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019307 ! PAX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056292 name: Q494Z4_HUMAN def: "Paired box 3" [UniProtKB:Q494Z4] xref: EMBL:AAI01300.1 xref: EMBL:AAI01301.1 xref: EMBL:AAI01303.1 xref: EMBL:AAI14364.1 xref: UniProtKB:Q494Z4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019307 ! PAX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056293 name: AKD1A_HUMAN def: "Ankyrin repeat and death domain-containing protein 1A precursor" [UniProtKB:Q495B1] xref: EMBL:AAI01274.1 xref: EMBL:AAI01275.1 xref: EMBL:AAI01276.1 xref: EMBL:BAC05399.1 xref: EMBL:BAC11532.1 xref: UniProtKB:Q495B1 xref: UniProtKB:Q495B2 xref: UniProtKB:Q495B3 xref: UniProtKB:Q8N7A0 xref: UniProtKB:Q8NBS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016946 ! ANKDD1A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056294 name: Q495I2_HUMAN def: "Taste receptor type 2" [UniProtKB:Q495I2] xref: EMBL:AAI01158.1 xref: EMBL:AAI01159.1 xref: UniProtKB:Q495I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020100 ! TAS2R41_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056295 name: Q495P6_HUMAN def: "Toll-like receptor 8" [UniProtKB:Q495P6] xref: EMBL:AAI01076.1 xref: UniProtKB:Q495P6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020283 ! TLR8_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056296 name: ZN672_HUMAN def: "Zinc finger protein 672" [UniProtKB:Q499Z4] xref: EMBL:AAH07385.2 xref: EMBL:AAH08872.1 xref: EMBL:AAH35140.1 xref: EMBL:AAH50348.1 xref: EMBL:AAH68506.1 xref: EMBL:BAB15294.1 xref: EMBL:BAB55290.1 xref: UniProtKB:Q499Z4 xref: UniProtKB:Q96H65 xref: UniProtKB:Q96IM3 xref: UniProtKB:Q9H6G5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020888 ! ZNF672_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056297 name: ZN732_HUMAN def: "Zinc finger protein 732" [UniProtKB:Q49A33] xref: EMBL:AAH46475.1 xref: UniProtKB:Q49A33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022813 ! ZNF732_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056298 name: Q49A40_HUMAN def: "LOC100129482 protein" [UniProtKB:Q49A40] xref: EMBL:AAH45697.1 xref: UniProtKB:Q49A40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021118 ! LOC100129482_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056299 name: ARF1L_HUMAN def: "Putative ADP-ribosylation factor 1-like" [UniProtKB:Q49A53] xref: EMBL:AAH45575.1 xref: EMBL:EAW93551.1 xref: UniProtKB:Q49A53 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056300 name: Q49A55_HUMAN def: "FGD4 protein" [UniProtKB:Q49A55] xref: EMBL:AAH45552.1 xref: UniProtKB:Q49A55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017787 ! FGD4_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056301 name: Q49A74_HUMAN def: "MYT1L protein" [UniProtKB:Q49A74] xref: EMBL:AAH43230.1 xref: UniProtKB:Q49A74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005152 ! MYT1L_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056302 name: ZN642_HUMAN def: "Zinc finger protein 642" [UniProtKB:Q49AA0] xref: EMBL:AAH41873.1 xref: EMBL:BAC85492.1 xref: EMBL:CAI16297.1 xref: UniProtKB:Q49AA0 xref: UniProtKB:Q5SWM5 xref: UniProtKB:Q6ZWK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020870 ! ZNF642_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056303 name: Q49AA3_HUMAN def: "ROCK1 protein" [UniProtKB:Q49AA3] xref: EMBL:AAH41849.1 xref: UniProtKB:Q49AA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019765 ! ROCK1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056304 name: CRY2_HUMAN def: "Cryptochrome-2" [UniProtKB:Q49AN0] xref: EMBL:AAH35161.1 xref: EMBL:AAH41814.1 xref: EMBL:BAA31633.1 xref: UniProtKB:O75148 xref: UniProtKB:Q49AN0 xref: UniProtKB:Q8IV71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017467 ! CRY2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000417 ! DNA photolyase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064521 ! CRY2_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0064522 ! CRY2_HUMAN-Phosphoserine558 [Term] id: CCO:B0056305 name: Q49AN3_HUMAN def: "ARHGEF1 protein" [UniProtKB:Q49AN3] xref: EMBL:AAH35127.1 xref: UniProtKB:Q49AN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004090 ! ARHGEF1_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056306 name: Q49AP2_HUMAN def: "RAP1GAP protein" [UniProtKB:Q49AP2] xref: EMBL:AAH35030.1 xref: UniProtKB:Q49AP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0056307 name: CERKL_HUMAN def: "Ceramide kinase-like protein" [UniProtKB:Q49MI3] xref: EMBL:AAR13670.1 xref: EMBL:AAW47988.1 xref: EMBL:AAW47989.1 xref: EMBL:AAW47990.1 xref: EMBL:AAW47991.1 xref: EMBL:AAW47992.1 xref: EMBL:BAC85266.1 xref: EMBL:CAG26695.1 xref: EMBL:CAG26977.1 xref: EMBL:CAG26978.1 xref: EMBL:CAG26980.1 xref: UniProtKB:Q49MH9 xref: UniProtKB:Q49MI0 xref: UniProtKB:Q49MI1 xref: UniProtKB:Q49MI2 xref: UniProtKB:Q49MI3 xref: UniProtKB:Q5DVJ2 xref: UniProtKB:Q5DVJ4 xref: UniProtKB:Q5DVJ5 xref: UniProtKB:Q6UZF6 xref: UniProtKB:Q6ZP59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017337 ! CERKL_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0056308 name: GPR33_HUMAN def: "Probable G-protein coupled receptor 33" [UniProtKB:Q49SQ1] xref: EMBL:AAR98754.1 xref: UniProtKB:Q49SQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018016 ! GPR33_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056309 name: Q4A519_HUMAN def: "ADP ribosylation factor-like protein 7" [UniProtKB:Q4A519] xref: EMBL:CAE30322.1 xref: UniProtKB:Q4A519 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021119 ! ARL7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0018887 ! ubqln4-arl7 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056310 name: Q4F7X0_HUMAN def: "Brain adenylate cyclase 8" [UniProtKB:Q4F7X0] xref: EMBL:AAZ13596.1 xref: UniProtKB:Q4F7X0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016913 ! ADCY8_human relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056311 name: Q4G0K7_HUMAN def: "GPR116 protein" [UniProtKB:Q4G0K7] xref: EMBL:AAH50087.1 xref: UniProtKB:Q4G0K7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017959 ! GPR116_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056312 name: Q4G0N1_HUMAN def: "ZNF283 protein" [UniProtKB:Q4G0N1] xref: EMBL:AAH45755.1 xref: UniProtKB:Q4G0N1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020693 ! ZNF283_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056313 name: Q4G0N6_HUMAN def: "CARD8 protein" [UniProtKB:Q4G0N6] xref: EMBL:AAH45539.1 xref: UniProtKB:Q4G0N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017231 ! CARD8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056314 name: Q4G0R5_HUMAN def: "RGL2 protein" [UniProtKB:Q4G0R5] xref: EMBL:AAH40989.1 xref: UniProtKB:Q4G0R5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019694 ! RGL2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0056315 name: HSF5_HUMAN def: "Heat shock factor protein 5" [UniProtKB:Q4G112] synonym: "Heat shock transcription factor 5" EXACT [UniProtKB:Q4G112] synonym: "HSF 5" EXACT [UniProtKB:Q4G112] synonym: "HSTF 5" EXACT [UniProtKB:Q4G112] xref: EMBL:AAH33017.1 xref: EMBL:AAH33020.1 xref: EMBL:AAI15386.1 xref: EMBL:BAC05124.1 xref: UniProtKB:Q08EH7 xref: UniProtKB:Q4G112 xref: UniProtKB:Q8N7V2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018164 ! HSF5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056316 name: Q4JF27_HUMAN def: "cDNA FLJ90600 fis, clone PLACE1001401, highly similar to Membrane-spanning 4-domains subfamily A member 4A" [UniProtKB:Q4JF27] xref: EMBL:BAC11389.1 xref: UniProtKB:Q4JF27 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056317 name: Q4JNY2_HUMAN def: "Pol" [UniProtKB:Q4JNY2] xref: EMBL:AAY87453.1 xref: UniProtKB:Q4JNY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0056318 name: Q4KMP4_HUMAN def: "T protein" [UniProtKB:Q4KMP4] xref: EMBL:AAH98425.1 xref: UniProtKB:Q4KMP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017177 ! T_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056319 name: TB10B_HUMAN def: "TBC1 domain family member 10B" [UniProtKB:Q4KMP7] xref: EMBL:AAH50523.2 xref: EMBL:AAH63112.1 xref: EMBL:AAH72453.2 xref: EMBL:AAH93814.1 xref: EMBL:AAH93816.1 xref: EMBL:AAH98419.1 xref: EMBL:AAQ15206.1 xref: EMBL:BAA92086.1 xref: EMBL:BAB14454.1 xref: EMBL:CAB55908.1 xref: EMBL:EAW52256.1 xref: UniProtKB:Q4KMP7 xref: UniProtKB:Q6IN54 xref: UniProtKB:Q6P530 xref: UniProtKB:Q71RG7 xref: UniProtKB:Q86VC5 xref: UniProtKB:Q9H8Z2 xref: UniProtKB:Q9NUN6 xref: UniProtKB:Q9UFP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020154 ! TBC1D10B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071168 ! TB10B_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0071169 ! TB10B_HUMAN-Phosphoserine386 relationship: transforms_into CCO:B0071170 ! TB10B_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0071171 ! TB10B_HUMAN-Phosphoserine412 relationship: transforms_into CCO:B0071172 ! TB10B_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0071173 ! TB10B_HUMAN-Phosphothreonine434 [Term] id: CCO:B0056320 name: PLCH1_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1" [UniProtKB:Q4KWH8] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q4KWH8] synonym: "Phospholipase C-eta-1" EXACT [UniProtKB:Q4KWH8] synonym: "Phospholipase C-like protein 3" EXACT [UniProtKB:Q4KWH8] synonym: "PLC-eta-1" EXACT [UniProtKB:Q4KWH8] synonym: "PLC-L3" EXACT [UniProtKB:Q4KWH8] xref: EMBL:AAH43248.2 xref: EMBL:AAI13951.1 xref: EMBL:AAW22607.1 xref: EMBL:AAW22608.1 xref: EMBL:BAA83021.1 xref: EMBL:BAB14129.1 xref: EMBL:CAH18710.1 xref: UniProtKB:Q29RV9 xref: UniProtKB:Q4KWH8 xref: UniProtKB:Q4KWH9 xref: UniProtKB:Q68CN0 xref: UniProtKB:Q86XK4 xref: UniProtKB:Q9H9U2 xref: UniProtKB:Q9UPT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019435 ! PLCH1_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056321 name: Q4TT37_HUMAN def: "Mitochondrial ribosomal protein L28" [UniProtKB:Q4TT37] xref: EMBL:CAI95596.1 xref: UniProtKB:Q4TT37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019754 ! MRPL28_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000407 ! ribosome relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056322 name: Q4TT38_HUMAN def: "Mitochondrial ribosomal protein L28" [UniProtKB:Q4TT38] xref: EMBL:CAI95595.1 xref: UniProtKB:Q4TT38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019754 ! MRPL28_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000407 ! ribosome relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056323 name: Q4TT72_HUMAN def: "Regulator of G-protein signalling 11 (Regulator of G-protein signalling 11, isoform CRA_a)" [UniProtKB:Q4TT72] xref: EMBL:CAI95581.1 xref: EMBL:EAW85839.1 xref: UniProtKB:Q4TT72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019702 ! RGS11_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056324 name: Q4U0F0_HUMAN def: "Nuclear receptor subfamily 1, group I, member 3" [UniProtKB:Q4U0F0] xref: EMBL:AAY56401.1 xref: UniProtKB:Q4U0F0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056325 name: Z658B_HUMAN def: "Zinc finger protein 658B" [UniProtKB:Q4V348] xref: EMBL:BAC04610.1 xref: EMBL:CAI95420.1 xref: UniProtKB:Q4V348 xref: UniProtKB:Q8N946 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020533 ! ZNF658B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056326 name: Q4V771_HUMAN def: "TBC1D29 protein" [UniProtKB:Q4V771] xref: EMBL:AAH98126.1 xref: UniProtKB:Q4V771 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020170 ! TBC1D29_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056327 name: Q4VAJ4_HUMAN def: "Protein Wnt" [UniProtKB:Q4VAJ4] xref: EMBL:AAH96355.1 xref: UniProtKB:Q4VAJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020479 ! WNT10B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056328 name: Q4VAM2_HUMAN def: "Leucine-rich repeat-containing G protein-coupled receptor 5" [UniProtKB:Q4VAM2] xref: EMBL:AAH96324.1 xref: EMBL:AAH99650.1 xref: UniProtKB:Q4VAM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018482 ! LGR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056329 name: Q4VAU5_HUMAN def: "CDX1 protein" [UniProtKB:Q4VAU5] xref: EMBL:AAH96250.1 xref: UniProtKB:Q4VAU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011291 ! CDX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056330 name: Q4VBL7_HUMAN def: "Galanin receptor 1" [UniProtKB:Q4VBL7] xref: EMBL:AAH95530.1 xref: EMBL:EAW66603.1 xref: UniProtKB:Q4VBL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017861 ! GALR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001307 ! galanin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056331 name: BCL7A_HUMAN def: "B-cell CLL/lymphoma 7 protein family member A" [UniProtKB:Q4VC05] xref: EMBL:AAH94723.1 xref: EMBL:CAA62011.1 xref: UniProtKB:Q13843 xref: UniProtKB:Q4VC05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017138 ! BCL7A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0063792 ! BCL7A_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0063793 ! BCL7A_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0063794 ! BCL7A_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0063795 ! BCL7A_HUMAN-Phosphoserine207 [Term] id: CCO:B0056332 name: AMOT_HUMAN def: "Angiomotin" [UniProtKB:Q4VCS5] xref: EMBL:AAG01851.1 xref: EMBL:AAH94712.1 xref: EMBL:AAY24451.1 xref: EMBL:BAA83023.3 xref: UniProtKB:Q4VCS5 xref: UniProtKB:Q504X5 xref: UniProtKB:Q9HD27 xref: UniProtKB:Q9UPT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016962 ! AMOT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002237 ! positive regulation of blood vessel endothelial cell migration relationship: transforms_into CCO:B0065617 ! AMOT_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0065618 ! AMOT_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0065619 ! AMOT_HUMAN-Phosphoserine712 relationship: transforms_into CCO:B0065620 ! AMOT_HUMAN-Phosphothreonine1061 [Term] id: CCO:B0056333 name: Q4VY10_HUMAN def: "Oculocerebrorenal syndrome of Lowe (Oculocerebrorenal syndrome of Lowe, isoform CRA_c)" [UniProtKB:Q4VY10] xref: EMBL:CAI95695.1 xref: EMBL:EAX11832.1 xref: UniProtKB:Q4VY10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019038 ! OCRL_human relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056334 name: Q4W4C6_HUMAN def: "Peroxisome proliferative activated receptor gamma" [UniProtKB:Q4W4C6] xref: EMBL:CAD91389.1 xref: UniProtKB:Q4W4C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005362 ! PPARG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056335 name: TIGD2_HUMAN def: "Tigger transposable element-derived protein 2" [UniProtKB:Q4W5G0] xref: EMBL:AAY40951.1 xref: UniProtKB:Q4W5G0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020267 ! TIGD2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056336 name: Q4W5L4_HUMAN def: "Putative uncharacterized protein PDE5A" [UniProtKB:Q4W5L4] xref: EMBL:AAY40985.1 xref: UniProtKB:Q4W5L4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019342 ! PDE5A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056337 name: Q4ZFZ2_HUMAN def: "Putative uncharacterized protein FSHR" [UniProtKB:Q4ZFZ2] xref: EMBL:AAX88895.1 xref: UniProtKB:Q4ZFZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004661 ! FSHR_human relationship: has_function CCO:F0001304 ! follicle-stimulating hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056338 name: Q4ZG35_HUMAN xref: UniProtKB:Q4ZG35 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056339 name: Q4ZG44_HUMAN xref: UniProtKB:Q4ZG44 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056340 name: Q503B1_HUMAN def: "AKT interacting protein" [UniProtKB:Q503B1] xref: EMBL:AAH95401.1 xref: UniProtKB:Q503B1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006345 ! AKTIP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation [Term] id: CCO:B0056341 name: Q504T0_HUMAN def: "ZNF101 protein" [UniProtKB:Q504T0] xref: EMBL:AAH94808.1 xref: UniProtKB:Q504T0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020616 ! ZNF101_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056342 name: Q50KZ9_HUMAN def: "Bitter taste receptor T2R2" [UniProtKB:Q50KZ9] xref: EMBL:BAD97898.1 xref: EMBL:BAD97899.1 xref: UniProtKB:Q50KZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021123 ! Hosa(Biaka)-T2R2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056343 name: RHG29_HUMAN def: "Rho GTPase-activating protein 29" [UniProtKB:Q52LW3] synonym: "PTPL1-associated RhoGAP protein 1" EXACT [UniProtKB:Q52LW3] synonym: "Rho-type GTPase-activating protein 29" EXACT [UniProtKB:Q52LW3] xref: EMBL:AAB81012.1 xref: EMBL:AAH22483.1 xref: EMBL:AAH67839.1 xref: EMBL:AAH93741.1 xref: EMBL:AAH93767.1 xref: EMBL:BAD92110.1 xref: EMBL:CAH71750.1 xref: EMBL:CAH71751.1 xref: EMBL:EAW73051.1 xref: EMBL:EAW73052.1 xref: UniProtKB:O15463 xref: UniProtKB:Q52LW3 xref: UniProtKB:Q59H86 xref: UniProtKB:Q5VYZ0 xref: UniProtKB:Q6NVX2 xref: UniProtKB:Q8TBI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019727 ! ARHGAP29_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0069984 ! RHG29_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0069985 ! RHG29_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0069986 ! RHG29_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0069987 ! RHG29_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0069988 ! RHG29_HUMAN-Phosphoserine913 relationship: transforms_into CCO:B0069989 ! RHG29_HUMAN-Phosphoserine949 relationship: transforms_into CCO:B0069990 ! RHG29_HUMAN-Phosphoserine1019 relationship: transforms_into CCO:B0069991 ! RHG29_HUMAN-Phosphoserine1029 relationship: transforms_into CCO:B0069992 ! RHG29_HUMAN-Phosphoserine1146 [Term] id: CCO:B0056344 name: Z585B_HUMAN def: "Zinc finger protein 585B" [UniProtKB:Q52M93] synonym: "zinc finger protein 41-like protein" EXACT [UniProtKB:Q52M93] xref: EMBL:AAH93625.1 xref: EMBL:AAN61169.1 xref: EMBL:BAB55400.1 xref: UniProtKB:Q52M93 xref: UniProtKB:Q8IZD3 xref: UniProtKB:Q96JW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020532 ! ZNF585B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056345 name: Q52R92_HUMAN def: "OR4F4" [UniProtKB:Q52R92] xref: EMBL:AAX86699.1 xref: UniProtKB:Q52R92 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056346 name: Q52R94_HUMAN def: "OR4F17 isoform 2" [UniProtKB:Q52R94] xref: EMBL:AAX86697.1 xref: UniProtKB:Q52R94 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056347 name: Q53EM3_HUMAN def: "Krueppel-related zinc finger protein 1 (HKR1 protein) variant" [UniProtKB:Q53EM3] xref: EMBL:BAD97336.1 xref: UniProtKB:Q53EM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056348 name: TIGD5_HUMAN def: "Tigger transposable element-derived protein 5" [UniProtKB:Q53EQ6] xref: EMBL:AAH32632.1 xref: EMBL:BAB55398.1 xref: EMBL:BAD97303.1 xref: UniProtKB:Q53EQ6 xref: UniProtKB:Q8N5A1 xref: UniProtKB:Q96JW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020269 ! TIGD5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056349 name: CRTC2_HUMAN def: "CREB-regulated transcription coactivator 2" [UniProtKB:Q53ET0] synonym: "TORC-2" EXACT [UniProtKB:Q53ET0] synonym: "Transducer of CREB protein 2" EXACT [UniProtKB:Q53ET0] synonym: "Transducer of regulated cAMP response element-binding protein 2" EXACT [UniProtKB:Q53ET0] xref: EMBL:AAH53562.1 xref: EMBL:AAQ98857.1 xref: EMBL:BAD97279.1 xref: EMBL:CAI14017.1 xref: UniProtKB:Q53ET0 xref: UniProtKB:Q6UUV8 xref: UniProtKB:Q7Z3X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017463 ! CRTC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064488 ! CRTC2_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0064489 ! CRTC2_HUMAN-Phosphoserine70 relationship: transforms_into CCO:B0064490 ! CRTC2_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0064491 ! CRTC2_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0064492 ! CRTC2_HUMAN-Phosphotyrosine130 relationship: transforms_into CCO:B0064493 ! CRTC2_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0064494 ! CRTC2_HUMAN-Phosphothreonine169 relationship: transforms_into CCO:B0064495 ! CRTC2_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0064496 ! CRTC2_HUMAN-Phosphothreonine177 relationship: transforms_into CCO:B0064497 ! CRTC2_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0064498 ! CRTC2_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0064499 ! CRTC2_HUMAN-Phosphoserine393 relationship: transforms_into CCO:B0064500 ! CRTC2_HUMAN-Phosphoserine433 relationship: transforms_into CCO:B0064501 ! CRTC2_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0064502 ! CRTC2_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0064503 ! CRTC2_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0064504 ! CRTC2_HUMAN-Phosphothreonine501 relationship: transforms_into CCO:B0064505 ! CRTC2_HUMAN-Phosphoserine613 relationship: transforms_into CCO:B0064506 ! CRTC2_HUMAN-Phosphoserine624 [Term] id: CCO:B0056350 name: Q53EU2_HUMAN def: "GATA binding protein 6 variant" [UniProtKB:Q53EU2] xref: EMBL:BAD97267.1 xref: UniProtKB:Q53EU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0056351 name: Q53EW1_HUMAN def: "Peroxisome proliferative activated receptor gamma isoform 2 variant" [UniProtKB:Q53EW1] xref: EMBL:BAD97248.1 xref: UniProtKB:Q53EW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056352 name: Q53EY4_HUMAN def: "RAB31, member RAS oncogene family variant" [UniProtKB:Q53EY4] xref: EMBL:BAD97225.1 xref: UniProtKB:Q53EY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056353 name: Q53F22_HUMAN def: "Angiopoietin-like 1 variant" [UniProtKB:Q53F22] xref: EMBL:BAD97187.1 xref: UniProtKB:Q53F22 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056354 name: Q53F98_HUMAN def: "DNA primase" [UniProtKB:Q53F98] synonym: "EC 2.7.7.-" EXACT [UniProtKB:Q53F98] xref: EMBL:BAD97111.1 xref: UniProtKB:Q53F98 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000407 ! DNA primase activity relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000266 ! alpha DNA polymerase:primase complex relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000633 ! DNA replication, synthesis of RNA primer [Term] id: CCO:B0056355 name: Q53F99_HUMAN xref: UniProtKB:Q53F99 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056356 name: QORX_HUMAN def: "Putative quinone oxidoreductase" [UniProtKB:Q53FA7] synonym: "EC 1.-.-.-" EXACT [UniProtKB:Q53FA7] synonym: "p53-induced gene 3 protein" EXACT [UniProtKB:Q53FA7] synonym: "Tumor protein p53-inducible protein 3" EXACT [UniProtKB:Q53FA7] xref: EMBL:AAC39528.1 xref: EMBL:AAC39535.1 xref: EMBL:AAH00474.1 xref: EMBL:AAP35813.1 xref: EMBL:AAQ90166.1 xref: EMBL:AAY14665.1 xref: EMBL:ABB02183.1 xref: EMBL:BAD97102.1 xref: UniProtKB:O14679 xref: UniProtKB:O14685 xref: UniProtKB:Q38G78 xref: UniProtKB:Q53FA7 xref: UniProtKB:Q6JLE7 xref: UniProtKB:Q9BWB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019567 ! TP53I3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0019553 ! tp53i3-unc119 physical interaction relationship: participates_in CCO:I0019866 ! tp53i3-eef1g physical interaction relationship: participates_in CCO:I0019867 ! tp53i3-ubr1 physical interaction relationship: participates_in CCO:I0020488 ! tp53i3-fundc2 physical interaction relationship: participates_in CCO:P0000838 ! induction of apoptosis by oxidative stress relationship: transforms_into CCO:B0069656 ! QORX_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0056357 name: Q53FZ4_HUMAN def: "RAR-related orphan receptor C isoform a variant" [UniProtKB:Q53FZ4] xref: EMBL:BAD96857.1 xref: UniProtKB:Q53FZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056358 name: KLH12_HUMAN def: "Kelch-like protein 12" [UniProtKB:Q53G59] synonym: "CUL3-interacting protein 1" EXACT [UniProtKB:Q53G59] xref: EMBL:AAG17175.1 xref: EMBL:AAH03183.1 xref: EMBL:AAH04175.1 xref: EMBL:BAB55271.1 xref: EMBL:BAD96792.1 xref: UniProtKB:Q53G59 xref: UniProtKB:Q9HBX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018425 ! KLHL12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016167 ! atxn1-klhl12 physical interaction relationship: participates_in CCO:I0017603 ! atxn1-klhl12-1 physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0067384 ! KLH12_HUMAN-Phosphothreonine31 relationship: transforms_into CCO:B0067385 ! KLH12_HUMAN-Phosphothreonine36 [Term] id: CCO:B0056359 name: Q53GC2_HUMAN def: "RAB4A, member RAS oncogene family variant" [UniProtKB:Q53GC2] xref: EMBL:BAD96729.1 xref: UniProtKB:Q53GC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056360 name: ZN394_HUMAN def: "Zinc finger protein 394" [UniProtKB:Q53GI3] synonym: "Zinc finger protein with KRAB and SCAN domains 14" EXACT [UniProtKB:Q53GI3] xref: EMBL:AAH25241.1 xref: EMBL:AAH51847.1 xref: EMBL:AAT67053.1 xref: EMBL:BAB14021.1 xref: EMBL:BAD96668.1 xref: UniProtKB:Q53GI3 xref: UniProtKB:Q6P5X9 xref: UniProtKB:Q8TB27 xref: UniProtKB:Q9HA37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020727 ! ZNF394_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056361 name: Q53GP0_HUMAN def: "Egf-like module containing, mucin-like, hormone receptor-like sequence 2 isoform e variant" [UniProtKB:Q53GP0] xref: EMBL:BAD96611.1 xref: UniProtKB:Q53GP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056362 name: AGK_HUMAN def: "Acylglycerol kinase, mitochondrial precursor" [UniProtKB:Q53H12] synonym: "EC 2.7.1.107" EXACT [UniProtKB:Q53H12] synonym: "EC 2.7.1.94" EXACT [UniProtKB:Q53H12] synonym: "hAGK" EXACT [UniProtKB:Q53H12] synonym: "HsMuLK" EXACT [UniProtKB:Q53H12] synonym: "MuLK" EXACT [UniProtKB:Q53H12] synonym: "Multi-substrate lipid kinase" EXACT [UniProtKB:Q53H12] synonym: "Multiple substrate lipid kinase" EXACT [UniProtKB:Q53H12] xref: EMBL:AAH09775.1 xref: EMBL:AAH22777.1 xref: EMBL:AAS07537.1 xref: EMBL:BAA91848.1 xref: EMBL:BAD96489.1 xref: EMBL:CAB93536.1 xref: UniProtKB:Q53H12 xref: UniProtKB:Q75KN1 xref: UniProtKB:Q96GC3 xref: UniProtKB:Q9NP48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016931 ! AGK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000205 ! ceramide kinase activity relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006922 ! acylglycerol kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0056363 name: LBH_HUMAN def: "Protein LBH" [UniProtKB:Q53QV2] synonym: "hLBH" EXACT [UniProtKB:Q53QV2] xref: EMBL:AAI09377.1 xref: EMBL:AAI26435.1 xref: EMBL:AAI30416.1 xref: EMBL:AAY24349.1 xref: EMBL:ABK30936.1 xref: EMBL:BAD97261.1 xref: EMBL:CAB66638.1 xref: UniProtKB:Q53QV2 xref: UniProtKB:Q9H0Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018459 ! LBH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067595 ! LBH_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0067596 ! LBH_HUMAN-Phosphothreonine69 [Term] id: CCO:B0056364 name: Q53S08_HUMAN def: "Putative uncharacterized protein RAB6C (Rab6C)" [UniProtKB:Q53S08] xref: EMBL:AAX93251.1 xref: EMBL:BAF02860.1 xref: UniProtKB:Q53S08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019604 ! RAB6C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056365 name: Q53SN3_HUMAN def: "Putative uncharacterized protein RAMP1" [UniProtKB:Q53SN3] xref: EMBL:AAY24219.1 xref: UniProtKB:Q53SN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019620 ! RAMP1_human relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056366 name: TAF1B_HUMAN def: "TATA box-binding protein-associated factor RNA polymerase I subunit B" [UniProtKB:Q53T94] synonym: "TAFI63" EXACT [UniProtKB:Q53T94] synonym: "TATA box-binding protein-associated factor 1B" EXACT [UniProtKB:Q53T94] synonym: "TBP-associated factor 1B" EXACT [UniProtKB:Q53T94] synonym: "TBP-associated factor RNA polymerase I 63 kDa" EXACT [UniProtKB:Q53T94] synonym: "Transcription factor SL1" EXACT [UniProtKB:Q53T94] xref: EMBL:AAA62863.1 xref: EMBL:AAH18137.1 xref: EMBL:AAX93272.1 xref: UniProtKB:Q15574 xref: UniProtKB:Q53T94 xref: UniProtKB:Q8WVC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020132 ! TAF1B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056367 name: Q53TN0_HUMAN def: "Putative uncharacterized protein ASB3" [UniProtKB:Q53TN0] xref: EMBL:AAX93180.1 xref: UniProtKB:Q53TN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017067 ! ASB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056368 name: Q53YA0_HUMAN def: "Gastrin-releasing peptide" [UniProtKB:Q53YA0] synonym: "Gastrin-releasing peptide, isoform CRA_a" EXACT [UniProtKB:Q53YA0] xref: EMBL:AAP35449.1 xref: EMBL:EAW63091.1 xref: UniProtKB:Q53YA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018080 ! GRP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056369 name: Q53YE0_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q53YE0] synonym: "cDNA, FLJ95705, highly similar to Homo sapiens GATA binding protein 2 (GATA2), mRNA" EXACT [UniProtKB:Q53YE0] xref: EMBL:AAP35317.1 xref: EMBL:BAG37347.1 xref: UniProtKB:Q53YE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056370 name: Q54AJ0_HUMAN def: "GDS-related protein" [UniProtKB:Q54AJ0] xref: EMBL:BAA36193.1 xref: UniProtKB:Q54AJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021124 ! HKE1.5_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056371 name: Q562E5_HUMAN def: "KIAA0194 protein" [UniProtKB:Q562E5] xref: EMBL:AAH92520.1 xref: UniProtKB:Q562E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021125 ! KIAA0194_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056372 name: Q569L6_HUMAN def: "Rap guanine nucleotide exchange factor (GEF) 3" [UniProtKB:Q569L6] xref: EMBL:AAH92404.1 xref: UniProtKB:Q569L6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019786 ! RAPGEF3_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0056373 name: Q56UN9_HUMAN def: "RAB18 long isoform 1" [UniProtKB:Q56UN9] xref: EMBL:AAU08232.1 xref: UniProtKB:Q56UN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019575 ! RAB18_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056374 name: Q57Z87_HUMAN def: "Putative uncharacterized protein NTSR2 (Neurotensin receptor 2, isoform CRA_c)" [UniProtKB:Q57Z87] xref: EMBL:AAX82018.1 xref: EMBL:EAX00924.1 xref: UniProtKB:Q57Z87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018884 ! NTSR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003173 ! neurotensin receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056375 name: PKHG4_HUMAN def: "Puratrophin-1" [UniProtKB:Q58EX7] synonym: "Pleckstrin homology domain-containing family G member 4" EXACT [UniProtKB:Q58EX7] synonym: "Purkinje cell atrophy-associated protein 1" EXACT [UniProtKB:Q58EX7] xref: EMBL:AAH54486.1 xref: EMBL:AAH63501.1 xref: EMBL:AAH82974.1 xref: EMBL:BAB15765.1 xref: EMBL:BAE07054.1 xref: EMBL:BAE07055.1 xref: EMBL:CAB55923.1 xref: UniProtKB:Q4G0J8 xref: UniProtKB:Q4H485 xref: UniProtKB:Q56A69 xref: UniProtKB:Q58EX7 xref: UniProtKB:Q9H7K4 xref: UniProtKB:Q9UFW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019416 ! PLEKHG4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019136 ! coil-plekhg4 physical interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0069354 ! PKHG4_HUMAN-Phosphoserine64 [Term] id: CCO:B0056376 name: Q58F03_HUMAN def: "ZNF180 protein" [UniProtKB:Q58F03] synonym: "Zinc finger protein 180" EXACT [UniProtKB:Q58F03] synonym: "Zinc finger protein 180 (HHZ168), isoform CRA_c" EXACT [UniProtKB:Q58F03] xref: EMBL:AAH33642.1 xref: EMBL:AAI13016.1 xref: EMBL:EAW57276.1 xref: UniProtKB:Q58F03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020641 ! ZNF180_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056377 name: BRDT_HUMAN def: "Bromodomain testis-specific protein" [UniProtKB:Q58F21] synonym: "Cancer/testis antigen 9" EXACT [UniProtKB:Q58F21] synonym: "CT9" EXACT [UniProtKB:Q58F21] synonym: "RING3-like protein" EXACT [UniProtKB:Q58F21] xref: EMBL:AAB87862.1 xref: EMBL:AAH17582.1 xref: EMBL:AAH47900.1 xref: EMBL:AAH62700.1 xref: EMBL:AAQ16198.1 xref: UniProtKB:O14789 xref: UniProtKB:Q58F21 xref: UniProtKB:Q6P5T1 xref: UniProtKB:Q7Z4A6 xref: UniProtKB:Q8IWI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017179 ! BRDT_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056378 name: Q59ED4_HUMAN def: "Aryl hydrocarbon receptor nuclear translocator isoform 1 variant" [UniProtKB:Q59ED4] xref: EMBL:BAD93114.1 xref: UniProtKB:Q59ED4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056379 name: Q59EI7_HUMAN def: "Cytoplasmic nuclear factor of activated T-cells 3 isoform 4 variant" [UniProtKB:Q59EI7] xref: EMBL:BAD93061.1 xref: UniProtKB:Q59EI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056380 name: RUN3A_HUMAN def: "RUN domain-containing protein 3A" [UniProtKB:Q59EK9] synonym: "Rap2-interacting protein 8" EXACT [UniProtKB:Q59EK9] synonym: "RPIP8 protein" EXACT [UniProtKB:Q59EK9] xref: EMBL:AAB68767.1 xref: EMBL:AAC09366.1 xref: EMBL:AAH06194.1 xref: EMBL:BAD93039.1 xref: EMBL:CAB63771.1 xref: EMBL:CAD97685.1 xref: EMBL:CAG33029.1 xref: EMBL:EAW51609.1 xref: EMBL:EAW51610.1 xref: UniProtKB:O15483 xref: UniProtKB:O60651 xref: UniProtKB:Q59EK9 xref: UniProtKB:Q7Z3S2 xref: UniProtKB:Q9UF50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019814 ! RUNDC3A_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056381 name: Q59EM3_HUMAN def: "Chimerin (Chimaerin) 1 variant" [UniProtKB:Q59EM3] xref: EMBL:BAD93025.1 xref: UniProtKB:Q59EM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056382 name: Q59EP4_HUMAN def: "Mel transforming oncogene variant" [UniProtKB:Q59EP4] xref: EMBL:BAD93004.1 xref: UniProtKB:Q59EP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056383 name: Q59EQ0_HUMAN def: "Special AT-rich sequence binding protein 1 variant" [UniProtKB:Q59EQ0] xref: EMBL:BAD92998.1 xref: UniProtKB:Q59EQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056384 name: Q59F03_HUMAN def: "Integrin alpha 3 isoform b, variant" [UniProtKB:Q59F03] xref: EMBL:BAD92895.1 xref: UniProtKB:Q59F03 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0056385 name: Q59F26_HUMAN def: "Diacylglycerol kinase, zeta 104kDa isoform 3 variant" [UniProtKB:Q59F26] xref: EMBL:BAD92872.1 xref: UniProtKB:Q59F26 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0056386 name: Q59F39_HUMAN def: "IL2-inducible T-cell kinase variant" [UniProtKB:Q59F39] xref: EMBL:BAD92859.1 xref: UniProtKB:Q59F39 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056387 name: Q59F61_HUMAN def: "CASP8 and FADD-like apoptosis regulator variant" [UniProtKB:Q59F61] xref: EMBL:BAD92837.1 xref: UniProtKB:Q59F61 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056388 name: Q59F62_HUMAN def: "Phospholipase C, delta 4 variant" [UniProtKB:Q59F62] xref: EMBL:BAD92836.1 xref: UniProtKB:Q59F62 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056389 name: Q59F87_HUMAN def: "Pleckstrin homology, Sec7 and coiled/coil domains 2 isoform 2 variant" [UniProtKB:Q59F87] xref: EMBL:BAD92810.1 xref: UniProtKB:Q59F87 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0056390 name: Q59FC3_HUMAN def: "G protein-coupled receptor kinase interactor 1 variant" [UniProtKB:Q59FC3] xref: EMBL:BAD92774.1 xref: UniProtKB:Q59FC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0056391 name: Q59FF1_HUMAN def: "Insulin-like growth factor binding protein 2 variant" [UniProtKB:Q59FF1] xref: EMBL:BAD92746.1 xref: UniProtKB:Q59FF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056392 name: Q59FL5_HUMAN def: "Ras inhibitor RIN1 variant" [UniProtKB:Q59FL5] xref: EMBL:BAD92682.1 xref: UniProtKB:Q59FL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056393 name: Q59FP4_HUMAN def: "Integrin-linked kinase variant" [UniProtKB:Q59FP4] xref: EMBL:BAD92653.1 xref: UniProtKB:Q59FP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0056394 name: Q59FQ0_HUMAN def: "Ras-related C3 botulinum toxin substrate 1 isoform Rac1b variant" [UniProtKB:Q59FQ0] xref: EMBL:BAD92647.1 xref: UniProtKB:Q59FQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056395 name: Q59FT1_HUMAN def: "T-box 2 variant" [UniProtKB:Q59FT1] xref: EMBL:BAD92615.1 xref: UniProtKB:Q59FT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056396 name: Q59G20_HUMAN def: "Beta isoform of regulatory subunit B56, protein phosphatase 2A variant" [UniProtKB:Q59G20] xref: EMBL:BAD92526.1 xref: UniProtKB:Q59G20 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056397 name: Q59G72_HUMAN def: "Neuropeptide Y receptor Y1 variant" [UniProtKB:Q59G72] xref: EMBL:BAD92474.1 xref: UniProtKB:Q59G72 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056398 name: Q59G74_HUMAN def: "Transcription factor-like protein 4 isoform alpha variant" [UniProtKB:Q59G74] xref: EMBL:BAD92472.1 xref: UniProtKB:Q59G74 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056399 name: Q59G81_HUMAN def: "Protein Wnt" [UniProtKB:Q59G81] xref: EMBL:BAD92465.1 xref: UniProtKB:Q59G81 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056400 name: Q59G99_HUMAN def: "Dishevelled 1 isoform a variant" [UniProtKB:Q59G99] xref: EMBL:BAD92447.1 xref: UniProtKB:Q59G99 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056401 name: Q59GA0_HUMAN def: "Thy-1 cell surface antigen variant" [UniProtKB:Q59GA0] xref: EMBL:BAD92446.1 xref: UniProtKB:Q59GA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0005537 ! GPI anchor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0001006 ! growth cone relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0002949 ! negative regulation of axonogenesis relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002978 ! negative regulation of T cell receptor signaling pathway relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation relationship: participates_in CCO:P0003076 ! positive regulation of release of sequestered calcium ion into cytosol [Term] id: CCO:B0056402 name: Q59GA7_HUMAN def: "Ets variant gene 1 variant" [UniProtKB:Q59GA7] xref: EMBL:BAD92439.1 xref: UniProtKB:Q59GA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056403 name: Q59GE2_HUMAN def: "Diacylglycerol kinase, iota variant" [UniProtKB:Q59GE2] xref: EMBL:BAD92404.1 xref: UniProtKB:Q59GE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056404 name: Q59GE8_HUMAN def: "RAS p21 protein activator 2 variant" [UniProtKB:Q59GE8] xref: EMBL:BAD92398.1 xref: UniProtKB:Q59GE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056405 name: Q59GG2_HUMAN def: "Caspase 9 isoform alpha preproprotein variant" [UniProtKB:Q59GG2] xref: EMBL:BAD92384.1 xref: UniProtKB:Q59GG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056406 name: Q59GG3_HUMAN def: "Transcription factor AP-4 (Activating enhancer binding protein 4) variant" [UniProtKB:Q59GG3] xref: EMBL:BAD92383.1 xref: UniProtKB:Q59GG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056407 name: Q59GJ1_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:Q59GJ1] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q59GJ1] xref: EMBL:BAD92355.1 xref: UniProtKB:Q59GJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0056408 name: Q59GK8_HUMAN def: "T-cell lymphoma invasion and metastasis 1 variant" [UniProtKB:Q59GK8] xref: EMBL:BAD92338.1 xref: UniProtKB:Q59GK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056409 name: Q59GL4_HUMAN def: "Cell division cycle 2-like 2 isoform 4 variant" [UniProtKB:Q59GL4] xref: EMBL:BAD92332.1 xref: UniProtKB:Q59GL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0056410 name: Q59GM0_HUMAN def: "Nuclear receptor co-repressor 2 variant" [UniProtKB:Q59GM0] xref: EMBL:BAD92326.1 xref: UniProtKB:Q59GM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056411 name: Q59GM6_HUMAN def: "PTK2 protein tyrosine kinase 2 isoform b variant" [UniProtKB:Q59GM6] xref: EMBL:BAD92320.1 xref: UniProtKB:Q59GM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: participates_in CCO:P0000714 ! signal complex assembly [Term] id: CCO:B0056412 name: Q59GR2_HUMAN def: "ELK1, member of ETS oncogene family variant" [UniProtKB:Q59GR2] xref: EMBL:BAD92284.1 xref: UniProtKB:Q59GR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056413 name: Q59GU9_HUMAN def: "Dual oxidase 2 variant" [UniProtKB:Q59GU9] xref: EMBL:BAD92247.1 xref: UniProtKB:Q59GU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0004249 ! heme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0056414 name: Q59GZ2_HUMAN def: "PLEK protein variant" [UniProtKB:Q59GZ2] xref: EMBL:BAD92204.1 xref: UniProtKB:Q59GZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056415 name: Q59HE9_HUMAN def: "Zinc finger protein 250 variant" [UniProtKB:Q59HE9] xref: EMBL:BAD92047.1 xref: UniProtKB:Q59HE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056416 name: Q59HG0_HUMAN def: "Pleckstrin and Sec7 domain containing 4 variant" [UniProtKB:Q59HG0] xref: EMBL:BAD92035.1 xref: UniProtKB:Q59HG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0056417 name: Q59HG6_HUMAN def: "Rho GTPase activating protein 6 isoform 1 variant" [UniProtKB:Q59HG6] xref: EMBL:BAD92029.1 xref: UniProtKB:Q59HG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056418 name: TMM97_HUMAN def: "Transmembrane protein 97" [UniProtKB:Q5BJF2] synonym: "Protein MAC30" EXACT [UniProtKB:Q5BJF2] xref: EMBL:AAA16188.1 xref: EMBL:AAH91504.1 xref: UniProtKB:Q07823 xref: UniProtKB:Q5BJF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020291 ! TMEM97_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056419 name: ZN805_HUMAN def: "Zinc finger protein 805" [UniProtKB:Q5CZA5] xref: EMBL:CAI56760.1 xref: UniProtKB:Q5CZA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020949 ! ZNF805_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056420 name: Q5CZI3_HUMAN def: "Putative uncharacterized protein DKFZp686C13142" [UniProtKB:Q5CZI3] xref: EMBL:CAI56712.1 xref: UniProtKB:Q5CZI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021126 ! DKFZp686C13142_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056421 name: ZC12A_HUMAN def: "Zinc finger CCCH domain-containing protein 12A" [UniProtKB:Q5D1E8] synonym: "MCP-induced protein 1" EXACT [UniProtKB:Q5D1E8] xref: EMBL:AAH05001.1 xref: EMBL:AAX14017.1 xref: EMBL:BAB15581.1 xref: EMBL:CAG33645.1 xref: EMBL:CAH73689.1 xref: EMBL:CAI20551.1 xref: EMBL:EAX07346.1 xref: UniProtKB:Q5D1E8 xref: UniProtKB:Q6I9Z1 xref: UniProtKB:Q9H5P1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020573 ! ZC3H12A_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056422 name: IGS11_HUMAN def: "Immunoglobulin superfamily member 11 precursor" [UniProtKB:Q5DX21] synonym: "Brain and testis-specific immunoglobulin superfamily protein" EXACT [UniProtKB:Q5DX21] synonym: "Bt-IGSF" EXACT [UniProtKB:Q5DX21] synonym: "V-set and immunoglobulin domain-containing protein 3" EXACT [UniProtKB:Q5DX21] xref: EMBL:AAH34411.1 xref: EMBL:BAC05139.1 xref: EMBL:BAD90695.1 xref: EMBL:CAD38931.1 xref: UniProtKB:Q5DX21 xref: UniProtKB:Q8N4F1 xref: UniProtKB:Q8N7T8 xref: UniProtKB:Q8NDD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018238 ! IGSF11_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056423 name: ZN628_HUMAN def: "Zinc finger protein 628" [UniProtKB:Q5EBL2] xref: EMBL:AAH47332.1 xref: EMBL:AAH89449.1 xref: UniProtKB:Q5EBL2 xref: UniProtKB:Q86X34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020865 ! ZNF628_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056424 name: ZN542_HUMAN def: "Zinc finger protein 542" [UniProtKB:Q5EBM4] xref: EMBL:AAH89419.1 xref: EMBL:CAE45809.1 xref: UniProtKB:Q5EBM4 xref: UniProtKB:Q6N061 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020805 ! ZNF542_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056425 name: Q5ECL3_HUMAN def: "Regulator of calcineurin 3 isoform 2,5" [UniProtKB:Q5ECL3] xref: EMBL:AAW83514.1 xref: UniProtKB:Q5ECL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021026 ! DSCR1L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0056426 name: Q5FBY4_HUMAN def: "Interferon regulatory factor 3 nirs variant 1" [UniProtKB:Q5FBY4] xref: EMBL:BAD89413.1 xref: UniProtKB:Q5FBY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018313 ! IRF3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056427 name: ZN789_HUMAN def: "Zinc finger protein 789" [UniProtKB:Q5FWF6] xref: EMBL:AAH89424.2 xref: EMBL:BAD18576.1 xref: EMBL:EAL23875.1 xref: EMBL:EAL23876.1 xref: UniProtKB:A4D282 xref: UniProtKB:Q5FWF6 xref: UniProtKB:Q6ZMZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020942 ! ZNF789_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056428 name: Q5FWG1_HUMAN def: "Diacylglycerol kinase, gamma 90kDa" [UniProtKB:Q5FWG1] xref: EMBL:AAH89411.1 xref: UniProtKB:Q5FWG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017568 ! DGKG_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056429 name: Q5GJ68_HUMAN def: "Hypothetical rhabdomyosarcoma antigen MU-RMS-40.2A" [UniProtKB:Q5GJ68] xref: EMBL:AAT44527.1 xref: UniProtKB:Q5GJ68 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056430 name: NMS_HUMAN def: "Neuromedin-S precursor" [UniProtKB:Q5H8A3] xref: EMBL:BAD89024.1 xref: UniProtKB:Q5H8A3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018809 ! NMS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0068754 ! NMS_HUMAN-Asparagine amide141 [Term] id: CCO:B0056431 name: Q5H8W3_HUMAN def: "Laminin, alpha 4" [UniProtKB:Q5H8W3] xref: EMBL:CAI42332.1 xref: UniProtKB:Q5H8W3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004968 ! LAMA4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0056432 name: Q5H8Y7_HUMAN def: "L(3)mbt-like (Drosophila)" [UniProtKB:Q5H8Y7] xref: EMBL:CAI42311.1 xref: UniProtKB:Q5H8Y7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018504 ! L3MBTL_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056433 name: Q5H8Y9_HUMAN def: "L(3)mbt-like (Drosophila)" [UniProtKB:Q5H8Y9] xref: EMBL:CAI23042.1 xref: EMBL:CAI42317.1 xref: UniProtKB:Q5H8Y9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018504 ! L3MBTL_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056434 name: Q5H914_HUMAN def: "Vestigial like 1 (Drosophila)" [UniProtKB:Q5H914] xref: EMBL:CAI42402.1 xref: UniProtKB:Q5H914 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020445 ! VGLL1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056435 name: Q5H915_HUMAN def: "Vestigial like 1 (Drosophila)" [UniProtKB:Q5H915] synonym: "Vestigial like 1 (Drosophila), isoform CRA_b" EXACT [UniProtKB:Q5H915] xref: EMBL:CAB10728.1 xref: EMBL:EAW88467.1 xref: UniProtKB:Q5H915 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020445 ! VGLL1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056436 name: Q5H999_HUMAN xref: UniProtKB:Q5H999 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056437 name: Q5H9B2_HUMAN def: "Ras-binding protein DA-Raf" [UniProtKB:Q5H9B2] synonym: "V-raf murine sarcoma 3611 viral oncogene homolog" EXACT [UniProtKB:Q5H9B2] xref: EMBL:BAE66645.1 xref: EMBL:CAI42469.1 xref: UniProtKB:Q5H9B2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004087 ! ARAF_human relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056438 name: BCORL_HUMAN def: "BCoR-like protein 1" [UniProtKB:Q5H9F3] synonym: "BCL6 corepressor-like protein 1" EXACT [UniProtKB:Q5H9F3] synonym: "BCoR-L1" EXACT [UniProtKB:Q5H9F3] xref: EMBL:BAB84915.1 xref: EMBL:BAC85922.1 xref: EMBL:CAB46626.1 xref: EMBL:CAI42768.1 xref: EMBL:CAI42769.1 xref: EMBL:CAI42770.1 xref: EMBL:CAI42884.1 xref: EMBL:CAI42885.1 xref: UniProtKB:Q5H9F2 xref: UniProtKB:Q5H9F3 xref: UniProtKB:Q5H9F4 xref: UniProtKB:Q6ZVE0 xref: UniProtKB:Q8TEN3 xref: UniProtKB:Q9Y528 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022071 ! BCORL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065794 ! BCORL_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0065795 ! BCORL_HUMAN-Phosphoserine613 relationship: transforms_into CCO:B0065796 ! BCORL_HUMAN-Phosphoserine1033 relationship: transforms_into CCO:B0065797 ! BCORL_HUMAN-Phosphoserine1162 [Term] id: CCO:B0056439 name: TCAL5_HUMAN def: "Transcription elongation factor A protein-like 5" [UniProtKB:Q5H9L2] synonym: "TCEA-like protein 5" EXACT [UniProtKB:Q5H9L2] synonym: "Transcription elongation factor S-II protein-like 5" EXACT [UniProtKB:Q5H9L2] xref: EMBL:CAI41976.1 xref: UniProtKB:Q5H9L2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020204 ! TCEAL5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056440 name: TAF7L_HUMAN def: "Transcription initiation factor TFIID subunit 7-like" [UniProtKB:Q5H9L4] synonym: "Cancer/testis antigen 40" EXACT [UniProtKB:Q5H9L4] synonym: "CT40" EXACT [UniProtKB:Q5H9L4] synonym: "RNA polymerase II TBP-associated factor subunit Q" EXACT [UniProtKB:Q5H9L4] synonym: "TATA box-binding protein-associated factor 50 kDa" EXACT [UniProtKB:Q5H9L4] synonym: "Transcription initiation factor TFIID 50 kDa subunit" EXACT [UniProtKB:Q5H9L4] xref: EMBL:AAH43391.1 xref: EMBL:AAK31974.1 xref: EMBL:BAB15560.1 xref: EMBL:CAI42014.1 xref: EMBL:CAI42015.1 xref: EMBL:CAI42017.1 xref: EMBL:CAI43034.1 xref: EMBL:CAI43035.1 xref: EMBL:CAI43036.1 xref: EMBL:EAX02847.1 xref: EMBL:EAX02848.1 xref: UniProtKB:Q5H9L4 xref: UniProtKB:Q5H9L6 xref: UniProtKB:Q86XI4 xref: UniProtKB:Q9BXU5 xref: UniProtKB:Q9H5R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020139 ! TAF7L_human relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056441 name: Q5HCI0_HUMAN def: "Putative uncharacterized protein DKFZp686D0345" [UniProtKB:Q5HCI0] xref: EMBL:CAI46254.1 xref: UniProtKB:Q5HCI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021127 ! DKFZp686D0345_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056442 name: ZN766_HUMAN def: "Zinc finger protein 766" [UniProtKB:Q5HY98] xref: EMBL:CAD98055.1 xref: EMBL:CAI45991.1 xref: UniProtKB:Q5HY98 xref: UniProtKB:Q7Z326 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020927 ! ZNF766_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056443 name: Q5HYD7_HUMAN def: "Putative uncharacterized protein DKFZp686K101" [UniProtKB:Q5HYD7] xref: EMBL:CAI46087.1 xref: UniProtKB:Q5HYD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021128 ! DKFZp686K101_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056444 name: RABL3_HUMAN def: "Rab-like protein 3" [UniProtKB:Q5HYI8] xref: EMBL:AAH20832.1 xref: EMBL:BAF85774.1 xref: EMBL:CAI46059.1 xref: EMBL:CAI46064.1 xref: EMBL:CAI46095.1 xref: EMBL:EAW79521.1 xref: UniProtKB:Q5HYI8 xref: UniProtKB:Q8WUD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019611 ! RABL3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056445 name: DMRTC_HUMAN def: "Doublesex- and mab-3-related transcription factor C1" [UniProtKB:Q5HYR2] xref: EMBL:AAH29799.1 xref: EMBL:AAH47596.1 xref: EMBL:CAC40653.1 xref: EMBL:CAI41255.1 xref: EMBL:CAI41256.1 xref: EMBL:CAI41258.1 xref: UniProtKB:Q5HYR0 xref: UniProtKB:Q5HYR2 xref: UniProtKB:Q5U5K2 xref: UniProtKB:Q8N6L3 xref: UniProtKB:Q96SD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017592 ! DMRTC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056446 name: Q5IFH6_HUMAN def: "G-protein coupled receptor 24 isoform 1" [UniProtKB:Q5IFH6] xref: EMBL:AAV98053.1 xref: UniProtKB:Q5IFH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021129 ! GPR24_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0004369 ! melanin-concentrating hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056447 name: Q5IRN4_HUMAN def: "Myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein" [UniProtKB:Q5IRN4] xref: EMBL:AAV91783.1 xref: UniProtKB:Q5IRN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021130 ! MEF2D/DAZAP1 fusion_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056448 name: Q5ISC7_HUMAN def: "Predicted NUP98/PRRX2 fusion protein" [UniProtKB:Q5ISC7] xref: EMBL:AAV84357.1 xref: UniProtKB:Q5ISC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056449 name: M4A13_HUMAN def: "Membrane-spanning 4-domains subfamily A member 13" [UniProtKB:Q5J8X5] synonym: "Testis-expressed transmembrane protein 4" EXACT [UniProtKB:Q5J8X5] xref: EMBL:AAQ94112.1 xref: EMBL:AAQ94113.1 xref: EMBL:AAQ94114.1 xref: UniProtKB:Q5J8X3 xref: UniProtKB:Q5J8X4 xref: UniProtKB:Q5J8X5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018542 ! MS4A13_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056450 name: Q5JBS6_HUMAN def: "WISP1i" [UniProtKB:Q5JBS6] xref: EMBL:AAP43926.1 xref: UniProtKB:Q5JBS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013647 ! WISP1_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0056451 name: ZN311_HUMAN def: "Zinc finger protein 311" [UniProtKB:Q5JNZ3] synonym: "Zinc finger protein zfp-31" EXACT [UniProtKB:Q5JNZ3] xref: EMBL:AAB16812.1 xref: EMBL:CAI18241.2 xref: EMBL:CAI41641.2 xref: EMBL:CAI41765.2 xref: UniProtKB:Q5JNZ3 xref: UniProtKB:Q92971 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020699 ! ZNF311_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056452 name: Q5JPD2_HUMAN def: "Putative uncharacterized protein DKFZp667A016" [UniProtKB:Q5JPD2] xref: EMBL:CAI46177.1 xref: UniProtKB:Q5JPD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021131 ! DKFZp667A016_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056453 name: Q5JPJ2_HUMAN def: "Putative uncharacterized protein DKFZp667L0117" [UniProtKB:Q5JPJ2] xref: EMBL:CAI46159.1 xref: UniProtKB:Q5JPJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021132 ! DKFZp667L0117_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056454 name: Q5JPN0_HUMAN def: "Connector enhancer of kinase suppressor of Ras 2 (Connector enhancer of kinase suppressor of Ras 2, isoform CRA_b)" [UniProtKB:Q5JPN0] xref: EMBL:CAH70863.1 xref: EMBL:CAI39866.1 xref: EMBL:CAI40765.1 xref: EMBL:EAW98977.1 xref: UniProtKB:Q5JPN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017406 ! CNKSR2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0056455 name: Q5JQ60_HUMAN def: "Synovial sarcoma, X breakpoint 5" [UniProtKB:Q5JQ60] xref: EMBL:CAI40523.1 xref: EMBL:CAI41133.1 xref: UniProtKB:Q5JQ60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020053 ! SSX5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056456 name: AKAP4_HUMAN def: "A-kinase anchor protein 4 precursor" [UniProtKB:Q5JQC9] synonym: "A-kinase anchor protein 82 kDa" EXACT [UniProtKB:Q5JQC9] synonym: "AKAP 82" EXACT [UniProtKB:Q5JQC9] synonym: "hAKAP82" EXACT [UniProtKB:Q5JQC9] synonym: "HI" EXACT [UniProtKB:Q5JQC9] synonym: "Major sperm fibrous sheath protein" EXACT [UniProtKB:Q5JQC9] synonym: "PRKA4" EXACT [UniProtKB:Q5JQC9] synonym: "Protein kinase A-anchoring protein 4" EXACT [UniProtKB:Q5JQC9] xref: EMBL:AAC79433.1 xref: EMBL:AAI26251.1 xref: EMBL:AAI26253.1 xref: EMBL:CAA75494.1 xref: EMBL:CAI41557.1 xref: EMBL:CAI41558.1 xref: EMBL:CAI41559.1 xref: EMBL:CAI41561.1 xref: UniProtKB:A0AV85 xref: UniProtKB:O60904 xref: UniProtKB:O95246 xref: UniProtKB:Q5JQC9 xref: UniProtKB:Q5JQD1 xref: UniProtKB:Q5JQD2 xref: UniProtKB:Q5JQD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016944 ! AKAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065536 ! AKAP4_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0065537 ! AKAP4_HUMAN-Phosphoserine63 relationship: transforms_into CCO:B0065538 ! AKAP4_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0065539 ! AKAP4_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0065540 ! AKAP4_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0065541 ! AKAP4_HUMAN-Phosphothreonine265 relationship: transforms_into CCO:B0065542 ! AKAP4_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0065543 ! AKAP4_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0065544 ! AKAP4_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0065545 ! AKAP4_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0065546 ! AKAP4_HUMAN-Phosphotyrosine303 relationship: transforms_into CCO:B0065547 ! AKAP4_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0065548 ! AKAP4_HUMAN-Phosphoserine447 relationship: transforms_into CCO:B0065549 ! AKAP4_HUMAN-Phosphotyrosine448 relationship: transforms_into CCO:B0065550 ! AKAP4_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0065551 ! AKAP4_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0065552 ! AKAP4_HUMAN-Phosphoserine536 relationship: transforms_into CCO:B0065553 ! AKAP4_HUMAN-Phosphoserine539 relationship: transforms_into CCO:B0065554 ! AKAP4_HUMAN-Phosphoserine665 relationship: transforms_into CCO:B0065555 ! AKAP4_HUMAN-Phosphoserine667 [Term] id: CCO:B0056457 name: Q5JQP3_HUMAN def: "Polymerase (DNA directed), lambda" [UniProtKB:Q5JQP3] xref: EMBL:CAI41034.1 xref: UniProtKB:Q5JQP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017609 ! POLL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0056458 name: Q5JQP8_HUMAN def: "Polymerase (DNA directed), lambda (Polymerase (DNA directed), lambda, isoform CRA_e)" [UniProtKB:Q5JQP8] xref: EMBL:CAI41029.1 xref: EMBL:EAW49761.1 xref: UniProtKB:Q5JQP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017609 ! POLL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0056459 name: OR2BB_HUMAN def: "Olfactory receptor 2B11" [UniProtKB:Q5JQS5] xref: EMBL:CAI17145.1 xref: UniProtKB:Q5JQS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019088 ! OR2B11_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056460 name: Q5JR05_HUMAN def: "Ras homolog gene family, member C" [UniProtKB:Q5JR05] xref: EMBL:CAI14057.1 xref: UniProtKB:Q5JR05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011656 ! RHOC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056461 name: Q5JR06_HUMAN def: "Ras homolog gene family, member C" [UniProtKB:Q5JR06] xref: EMBL:CAI14061.1 xref: UniProtKB:Q5JR06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011656 ! RHOC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056462 name: Q5JR07_HUMAN def: "Ras homolog gene family, member C" [UniProtKB:Q5JR07] xref: EMBL:CAI14060.1 xref: UniProtKB:Q5JR07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011656 ! RHOC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056463 name: MIA3_HUMAN def: "Melanoma inhibitory activity protein 3 precursor" [UniProtKB:Q5JRA6] synonym: "C219-reactive peptide" EXACT [UniProtKB:Q5JRA6] synonym: "D320" EXACT [UniProtKB:Q5JRA6] synonym: "Protein TANGO" EXACT [UniProtKB:Q5JRA6] xref: EMBL:AAB00324.1 xref: EMBL:AAH47116.2 xref: EMBL:AAQ89449.1 xref: EMBL:BAA13448.1 xref: EMBL:BAC04810.1 xref: EMBL:CAI40469.1 xref: EMBL:CAI40470.1 xref: EMBL:CAI40471.1 xref: EMBL:CAI40473.1 xref: UniProtKB:Q14083 xref: UniProtKB:Q5JRA5 xref: UniProtKB:Q5JRA6 xref: UniProtKB:Q5JRB1 xref: UniProtKB:Q5JRB2 xref: UniProtKB:Q6UVY8 xref: UniProtKB:Q86Y60 xref: UniProtKB:Q8N8M5 xref: UniProtKB:Q92580 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018615 ! MIA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000555 ! positive regulation of leukocyte migration relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: transforms_into CCO:B0068162 ! MIA3_HUMAN-Phosphothreonine382 relationship: transforms_into CCO:B0068163 ! MIA3_HUMAN-Phosphoserine727 relationship: transforms_into CCO:B0068164 ! MIA3_HUMAN-Phosphoserine1727 relationship: transforms_into CCO:B0068165 ! MIA3_HUMAN-Phosphoserine1739 relationship: transforms_into CCO:B0068166 ! MIA3_HUMAN-Phosphoserine1740 relationship: transforms_into CCO:B0068167 ! MIA3_HUMAN-Phosphoserine1892 relationship: transforms_into CCO:B0068168 ! MIA3_HUMAN-Phosphoserine1906 [Term] id: CCO:B0056464 name: Q5JRI7_HUMAN def: "Transcription elongation factor A (SII), 2" [UniProtKB:Q5JRI7] xref: EMBL:CAI13200.1 xref: UniProtKB:Q5JRI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005748 ! TCEA2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0056465 name: Q5JRI9_HUMAN def: "cDNA FLJ35350 fis, clone PUAEN1000065, highly similar to Homo sapiens TSC22 domain family, member 3 (TSC22D3), transcript variant 1, mRNA" [UniProtKB:Q5JRI9] synonym: "TSC22 domain family, member 3" EXACT [UniProtKB:Q5JRI9] synonym: "TSC22 domain family, member 3, isoform CRA_a" EXACT [UniProtKB:Q5JRI9] xref: EMBL:BAG52587.1 xref: EMBL:CAI41544.1 xref: EMBL:EAX02704.1 xref: UniProtKB:Q5JRI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020089 ! TSC22D3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056466 name: Q5JRJ0_HUMAN def: "TSC22 domain family, member 3" [UniProtKB:Q5JRJ0] xref: EMBL:CAI41543.1 xref: UniProtKB:Q5JRJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020089 ! TSC22D3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056467 name: Q5JRJ1_HUMAN def: "TSC22 domain family, member 3" [UniProtKB:Q5JRJ1] xref: EMBL:CAI41542.1 xref: UniProtKB:Q5JRJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020089 ! TSC22D3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056468 name: Q5JRJ2_HUMAN def: "TSC22 domain family, member 3" [UniProtKB:Q5JRJ2] xref: EMBL:CAI41541.1 xref: UniProtKB:Q5JRJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020089 ! TSC22D3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056469 name: Q5JRM1_HUMAN def: "Novel protein (Putative uncharacterized protein RP13-102H20.1)" [UniProtKB:Q5JRM1] xref: EMBL:CAI41398.1 xref: EMBL:EAX11793.1 xref: UniProtKB:Q5JRM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021133 ! RP13-102H20.1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056470 name: O10J3_HUMAN def: "Olfactory receptor 10J3" [UniProtKB:Q5JRS4] xref: EMBL:CAI15595.1 xref: UniProtKB:Q5JRS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018920 ! OR10J3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056471 name: Q5JRU8_HUMAN def: "Caspase 9, apoptosis-related cysteine peptidase" [UniProtKB:Q5JRU8] xref: EMBL:CAI12974.1 xref: UniProtKB:Q5JRU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004222 ! CASP9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056472 name: Q5JRY3_HUMAN def: "Transcription factor 7-like 2 (T-cell specific, HMG-box)" [UniProtKB:Q5JRY3] xref: EMBL:CAI40406.1 xref: UniProtKB:Q5JRY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005767 ! TCF7L2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056473 name: Q5JRY4_HUMAN def: "Transcription factor 7-like 2 (T-cell specific, HMG-box)" [UniProtKB:Q5JRY4] xref: EMBL:CAI40405.1 xref: UniProtKB:Q5JRY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005767 ! TCF7L2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056474 name: Q5JRZ7_HUMAN def: "Zinc finger protein 449" [UniProtKB:Q5JRZ7] xref: EMBL:CAI39872.1 xref: UniProtKB:Q5JRZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020757 ! ZNF449_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056475 name: Q5JS19_HUMAN def: "GTPase activating Rap/RanGAP domain-like 3" [UniProtKB:Q5JS19] xref: EMBL:CAI41455.1 xref: UniProtKB:Q5JS19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017865 ! GARNL3_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0056476 name: Q5JS98_HUMAN def: "Pre-B-cell leukemia homeobox 3" [UniProtKB:Q5JS98] xref: EMBL:CAH73696.1 xref: EMBL:CAI40242.1 xref: UniProtKB:Q5JS98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019315 ! PBX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056477 name: Q5JSD4_HUMAN def: "Rho GTPase activating protein 21" [UniProtKB:Q5JSD4] xref: EMBL:CAI40180.1 xref: UniProtKB:Q5JSD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019721 ! ARHGAP21_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056478 name: Q5JSD8_HUMAN def: "Rho GTPase activating protein 21" [UniProtKB:Q5JSD8] xref: EMBL:CAI40181.1 xref: UniProtKB:Q5JSD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019721 ! ARHGAP21_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056479 name: Q5JSM8_HUMAN def: "G protein-coupled receptor 101" [UniProtKB:Q5JSM8] xref: EMBL:CAI40047.1 xref: EMBL:EAW88450.1 xref: UniProtKB:Q5JSM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017953 ! GPR101_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056480 name: FGD3_HUMAN def: "FYVE, RhoGEF and PH domain-containing protein 3" [UniProtKB:Q5JSP0] synonym: "Zinc finger FYVE domain-containing protein 5" EXACT [UniProtKB:Q5JSP0] xref: EMBL:AAH32429.1 xref: EMBL:AAI11055.1 xref: EMBL:AAP20645.1 xref: EMBL:CAI41118.1 xref: EMBL:CAI95107.1 xref: UniProtKB:Q4VX84 xref: UniProtKB:Q5JSP0 xref: UniProtKB:Q7Z7D9 xref: UniProtKB:Q8N5G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017786 ! FGD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002156 ! regulation of Cdc42 GTPase activity relationship: transforms_into CCO:B0066179 ! FGD3_HUMAN-Phosphoserine128 [Term] id: CCO:B0056481 name: RAB41_HUMAN def: "Ras-related protein Rab-41" [UniProtKB:Q5JT25] xref: EMBL:CAI41489.1 xref: UniProtKB:Q5JT25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019597 ! RAB41_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056482 name: Q5JT55_HUMAN def: "T-box 15" [UniProtKB:Q5JT55] xref: EMBL:CAI43067.1 xref: UniProtKB:Q5JT55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008277 ! TBX15_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056483 name: KLF17_HUMAN def: "Krueppel-like factor 17" [UniProtKB:Q5JT82] synonym: "Zinc finger protein 393" EXACT [UniProtKB:Q5JT82] xref: EMBL:AAH49844.1 xref: EMBL:BAC05070.1 xref: EMBL:CAI15911.1 xref: UniProtKB:Q5JT82 xref: UniProtKB:Q86VQ7 xref: UniProtKB:Q8N805 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018415 ! KLF17_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056484 name: Q5JU31_HUMAN def: "cDNA FLJ31506 fis, clone NT2NE2005876, highly similar to SH2 domain-containing protein 3C" [UniProtKB:Q5JU31] synonym: "SH2 domain containing 3C" EXACT [UniProtKB:Q5JU31] xref: EMBL:BAG51614.1 xref: EMBL:CAI39761.1 xref: EMBL:CAI41177.1 xref: UniProtKB:Q5JU31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019889 ! SH2D3C_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056485 name: IQEC2_HUMAN def: "IQ motif and SEC7 domain-containing protein 2" [UniProtKB:Q5JU85] xref: EMBL:BAA25448.1 xref: EMBL:CAI39832.1 xref: EMBL:CAI42091.1 xref: UniProtKB:O60275 xref: UniProtKB:Q5JU85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018306 ! IQSEC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0067141 ! IQEC2_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0067142 ! IQEC2_HUMAN-Phosphotyrosine89 relationship: transforms_into CCO:B0067143 ! IQEC2_HUMAN-Phosphotyrosine611 relationship: transforms_into CCO:B0067144 ! IQEC2_HUMAN-Phosphotyrosine923 relationship: transforms_into CCO:B0067145 ! IQEC2_HUMAN-Phosphotyrosine1119 [Term] id: CCO:B0056486 name: Q5JU95_HUMAN xref: UniProtKB:Q5JU95 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056487 name: Q5JUE7_HUMAN def: "Rap guanine nucleotide exchange factor (GEF) 1" [UniProtKB:Q5JUE7] xref: EMBL:CAI40650.1 xref: UniProtKB:Q5JUE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011663 ! RAPGEF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056488 name: Q5JUH9_HUMAN def: "G protein-coupled receptor 18" [UniProtKB:Q5JUH9] xref: EMBL:CAI14307.1 xref: UniProtKB:Q5JUH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018005 ! GPR18_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056489 name: SOLH1_HUMAN def: "Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1" [UniProtKB:Q5JUK2] xref: EMBL:AAH31861.2 xref: EMBL:AAW78548.1 xref: EMBL:AAW82617.1 xref: EMBL:CAI39241.2 xref: EMBL:EAW88175.1 xref: UniProtKB:Q5EE14 xref: UniProtKB:Q5EGC2 xref: UniProtKB:Q5JUK2 xref: UniProtKB:Q8NEE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019978 ! SOHLH1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056490 name: ZN673_HUMAN def: "Protein ZNF673" [UniProtKB:Q5JUW0] xref: EMBL:AAH12569.1 xref: EMBL:BAA91104.1 xref: EMBL:CAI41301.1 xref: EMBL:CAI41302.1 xref: UniProtKB:Q5JUW0 xref: UniProtKB:Q96EA3 xref: UniProtKB:Q9NXB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020889 ! ZNF673_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056491 name: Q5JUX1_HUMAN def: "IQ motif and Sec7 domain 2" [UniProtKB:Q5JUX1] xref: EMBL:CAI39839.1 xref: UniProtKB:Q5JUX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018306 ! IQSEC2_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0056492 name: Q5JV91_HUMAN def: "FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived)" [UniProtKB:Q5JV91] xref: EMBL:CAI39454.1 xref: UniProtKB:Q5JV91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017763 ! FARP1_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056493 name: Q5JV94_HUMAN def: "FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived)" [UniProtKB:Q5JV94] xref: EMBL:CAI39451.1 xref: UniProtKB:Q5JV94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017763 ! FARP1_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056494 name: ZN484_HUMAN def: "Zinc finger protein 484" [UniProtKB:Q5JVG2] xref: EMBL:AAI12395.1 xref: EMBL:AAI12397.1 xref: EMBL:CAI41018.1 xref: UniProtKB:Q5JVG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020770 ! ZNF484_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056495 name: ZN506_HUMAN def: "Zinc finger protein 506" [UniProtKB:Q5JVG8] xref: EMBL:CAB66483.1 xref: UniProtKB:Q5JVG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020785 ! ZNF506_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056496 name: Q5JVT4_HUMAN def: "tRNA aspartic acid methyltransferase 1" [UniProtKB:Q5JVT4] xref: EMBL:CAI39482.1 xref: UniProtKB:Q5JVT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005826 ! TRDMT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0056497 name: Q5JW63_HUMAN def: "Putative uncharacterized protein DKFZp566E034" [UniProtKB:Q5JW63] xref: EMBL:CAI46217.1 xref: UniProtKB:Q5JW63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021134 ! DKFZp566E034_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0056498 name: Q5JXE6_HUMAN def: "Sex comb on midleg-like 2 (Drosophila) (Sex comb on midleg-like 2 (Drosophila), isoform CRA_a)" [UniProtKB:Q5JXE6] xref: EMBL:CAI42221.1 xref: EMBL:CAI43048.1 xref: EMBL:CAI43176.1 xref: EMBL:EAW98937.1 xref: UniProtKB:Q5JXE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019849 ! SCML2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056499 name: Q5JXL8_HUMAN def: "Putative uncharacterized protein DKFZp564G0422" [UniProtKB:Q5JXL8] xref: EMBL:CAI46227.1 xref: UniProtKB:Q5JXL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021135 ! DKFZp564G0422_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0002656 ! negative regulation of nucleotide metabolic process [Term] id: CCO:B0056500 name: Q5JXV8_HUMAN def: "Zinc finger protein 133" [UniProtKB:Q5JXV8] xref: EMBL:CAI21835.1 xref: UniProtKB:Q5JXV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020623 ! ZNF133_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056501 name: Q5JXV9_HUMAN def: "Zinc finger protein 133" [UniProtKB:Q5JXV9] xref: EMBL:CAI21834.1 xref: UniProtKB:Q5JXV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020623 ! ZNF133_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056502 name: Q5JXW0_HUMAN def: "Zinc finger protein 133" [UniProtKB:Q5JXW0] xref: EMBL:CAI21833.1 xref: UniProtKB:Q5JXW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020623 ! ZNF133_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056503 name: Q5JXW1_HUMAN def: "Zinc finger protein 133" [UniProtKB:Q5JXW1] xref: EMBL:CAI21832.1 xref: UniProtKB:Q5JXW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020623 ! ZNF133_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056504 name: Q5JY03_HUMAN def: "tRNA methyltransferase 11 homolog (S. cerevisiae)" [UniProtKB:Q5JY03] xref: EMBL:CAI42391.1 xref: UniProtKB:Q5JY03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021136 ! TRMT11_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001757 ! N-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0056505 name: Q5JY94_HUMAN def: "Duffy blood group, chemokine receptor" [UniProtKB:Q5JY94] xref: EMBL:CAI17895.1 xref: UniProtKB:Q5JY94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017629 ! DARC_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056506 name: Q5JYJ2_HUMAN def: "MCF.2 cell line derived transforming sequence (MCF.2 cell line derived transforming sequence, isoform CRA_e)" [UniProtKB:Q5JYJ2] xref: EMBL:CAI42108.1 xref: EMBL:EAW88430.1 xref: UniProtKB:Q5JYJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018586 ! MCF2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056507 name: Q5JYJ3_HUMAN def: "MCF.2 cell line derived transforming sequence (MCF.2 cell line derived transforming sequence, isoform CRA_b)" [UniProtKB:Q5JYJ3] xref: EMBL:CAI42107.1 xref: EMBL:EAW88427.1 xref: UniProtKB:Q5JYJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018586 ! MCF2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056508 name: Q5JYJ5_HUMAN def: "MCF.2 cell line derived transforming sequence" [UniProtKB:Q5JYJ5] xref: EMBL:CAI42106.1 xref: UniProtKB:Q5JYJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018586 ! MCF2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056509 name: Q5JYJ6_HUMAN def: "MCF.2 cell line derived transforming sequence" [UniProtKB:Q5JYJ6] xref: EMBL:CAI42105.1 xref: UniProtKB:Q5JYJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018586 ! MCF2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056510 name: Q5JYJ7_HUMAN def: "MCF.2 cell line derived transforming sequence" [UniProtKB:Q5JYJ7] xref: EMBL:CAI39715.1 xref: EMBL:CAI42104.1 xref: UniProtKB:Q5JYJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018586 ! MCF2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056511 name: Q5JYT3_HUMAN def: "Phospholipase C, beta 4" [UniProtKB:Q5JYT3] xref: EMBL:CAI42218.2 xref: EMBL:CAI43092.2 xref: UniProtKB:Q5JYT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019429 ! PLCB4_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056512 name: Q5JYX0_HUMAN def: "Cell division cycle 42 (GTP binding protein, 25kDa)" [UniProtKB:Q5JYX0] xref: EMBL:CAI19851.1 xref: UniProtKB:Q5JYX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004290 ! CDC42_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0056513 name: Q5JYX2_HUMAN def: "Protein Wnt" [UniProtKB:Q5JYX2] xref: EMBL:CAI19849.1 xref: UniProtKB:Q5JYX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020489 ! WNT4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056514 name: Q5JYZ5_HUMAN xref: UniProtKB:Q5JYZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056515 name: DGKK_HUMAN def: "Diacylglycerol kinase kappa" [UniProtKB:Q5KSL6] synonym: "142 kDa diacylglycerol kinase" EXACT [UniProtKB:Q5KSL6] synonym: "DAG kinase kappa" EXACT [UniProtKB:Q5KSL6] synonym: "DGK-kappa" EXACT [UniProtKB:Q5KSL6] synonym: "Diglyceride kinase kappa" EXACT [UniProtKB:Q5KSL6] synonym: "EC 2.7.1.107" EXACT [UniProtKB:Q5KSL6] xref: EMBL:BAD86792.1 xref: UniProtKB:Q5KSL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017571 ! DGKK_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064754 ! DGKK_HUMAN-Phosphotyrosine78 [Term] id: CCO:B0056516 name: Q5KU14_HUMAN def: "KPG_013 protein" [UniProtKB:Q5KU14] xref: EMBL:BAD83600.1 xref: UniProtKB:Q5KU14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021137 ! KPG_013_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056517 name: Q5KU19_HUMAN def: "G-protein coupled receptor" [UniProtKB:Q5KU19] xref: EMBL:BAD83596.1 xref: UniProtKB:Q5KU19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021138 ! KPG_009_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056518 name: Q5KU20_HUMAN def: "G-protein coupled receptor" [UniProtKB:Q5KU20] xref: EMBL:BAD83595.1 xref: UniProtKB:Q5KU20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021139 ! KPG_008_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056519 name: Q5KU21_HUMAN def: "G-protein coupled receptor" [UniProtKB:Q5KU21] xref: EMBL:BAD83594.1 xref: UniProtKB:Q5KU21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021140 ! KPG_007_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056520 name: Q5KU22_HUMAN def: "G-protein coupled receptor" [UniProtKB:Q5KU22] xref: EMBL:BAD83593.1 xref: UniProtKB:Q5KU22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021141 ! KPG_006_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056521 name: COL12_HUMAN def: "Collectin-12" [UniProtKB:Q5KU26] synonym: "CL-P1" EXACT [UniProtKB:Q5KU26] synonym: "Collectin placenta protein 1" EXACT [UniProtKB:Q5KU26] synonym: "hCL-P1" EXACT [UniProtKB:Q5KU26] synonym: "Nurse cell scavenger receptor 2" EXACT [UniProtKB:Q5KU26] synonym: "Scavenger receptor class A member 4" EXACT [UniProtKB:Q5KU26] synonym: "Scavenger receptor with C-type lectin" EXACT [UniProtKB:Q5KU26] xref: EMBL:AAH60789.1 xref: EMBL:BAB39147.1 xref: EMBL:BAB39148.1 xref: EMBL:BAB72147.1 xref: EMBL:BAD83592.1 xref: EMBL:CAD28466.1 xref: UniProtKB:Q5KU26 xref: UniProtKB:Q6P9F2 xref: UniProtKB:Q8TCR2 xref: UniProtKB:Q8WZA4 xref: UniProtKB:Q9BY85 xref: UniProtKB:Q9BYH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017434 ! COLEC12_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001365 ! scavenger receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001660 ! galactose binding relationship: has_function CCO:F0001838 ! pattern recognition receptor activity relationship: has_function CCO:F0004336 ! low-density lipoprotein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000862 ! carbohydrate mediated signaling [Term] id: CCO:B0056522 name: Q5M8T3_HUMAN def: "HES5 protein" [UniProtKB:Q5M8T3] xref: EMBL:AAH87840.1 xref: UniProtKB:Q5M8T3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018121 ! HES5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056523 name: ZN569_HUMAN def: "Zinc finger protein 569" [UniProtKB:Q5MCW4] xref: EMBL:AAA61321.1 xref: EMBL:AAV97944.1 xref: EMBL:BAB71232.1 xref: UniProtKB:Q15925 xref: UniProtKB:Q5MCW4 xref: UniProtKB:Q96MQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020826 ! ZNF569_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056524 name: GP120_HUMAN def: "G-protein coupled receptor 120" [UniProtKB:Q5NUL3] synonym: "G-protein coupled receptor 129" EXACT [UniProtKB:Q5NUL3] synonym: "G-protein coupled receptor GT01" EXACT [UniProtKB:Q5NUL3] synonym: "G-protein coupled receptor PGR4" EXACT [UniProtKB:Q5NUL3] xref: EMBL:AAO85085.1 xref: EMBL:AAP72126.1 xref: EMBL:BAD83368.1 xref: EMBL:CAH72326.1 xref: EMBL:CAH72327.1 xref: UniProtKB:Q5NUL3 xref: UniProtKB:Q5VY25 xref: UniProtKB:Q5VY26 xref: UniProtKB:Q7Z605 xref: UniProtKB:Q86SM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017961 ! GPR120_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056525 name: Q5QD39_HUMAN def: "Phosphodiesterase PDE9A21" [UniProtKB:Q5QD39] xref: EMBL:AAV84271.1 xref: UniProtKB:Q5QD39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019348 ! PDE9A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056526 name: TDIF2_HUMAN def: "Deoxynucleotidyltransferase terminal-interacting protein 2" [UniProtKB:Q5QJE6] synonym: "Estrogen receptor-binding protein" EXACT [UniProtKB:Q5QJE6] synonym: "LPTS-interacting protein 2" EXACT [UniProtKB:Q5QJE6] synonym: "LPTS-RP2" EXACT [UniProtKB:Q5QJE6] synonym: "TdT-interacting factor 2" EXACT [UniProtKB:Q5QJE6] synonym: "Terminal deoxynucleotidyltransferase-interacting factor 2" EXACT [UniProtKB:Q5QJE6] xref: EMBL:AAA50601.1 xref: EMBL:AAH47688.1 xref: EMBL:AAI30623.1 xref: EMBL:AAQ95169.1 xref: EMBL:AAR02407.1 xref: EMBL:BAD08331.1 xref: EMBL:BAD96442.1 xref: EMBL:BAF85068.1 xref: EMBL:CAI21812.1 xref: EMBL:EAW73064.1 xref: UniProtKB:Q12987 xref: UniProtKB:Q53H59 xref: UniProtKB:Q5QJE6 xref: UniProtKB:Q5TFJ4 xref: UniProtKB:Q6TLI0 xref: UniProtKB:Q76MJ8 xref: UniProtKB:Q86WX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020221 ! DNTTIP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071292 ! TDIF2_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0071293 ! TDIF2_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0071294 ! TDIF2_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0071295 ! TDIF2_HUMAN-Phosphothreonine129 relationship: transforms_into CCO:B0071296 ! TDIF2_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0071297 ! TDIF2_HUMAN-Phosphoserine145 relationship: transforms_into CCO:B0071298 ! TDIF2_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0071299 ! TDIF2_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0071300 ! TDIF2_HUMAN-Phosphothreonine188 relationship: transforms_into CCO:B0071301 ! TDIF2_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0071302 ! TDIF2_HUMAN-Phosphoserine190 relationship: transforms_into CCO:B0071303 ! TDIF2_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0071304 ! TDIF2_HUMAN-Phosphoserine194 relationship: transforms_into CCO:B0071305 ! TDIF2_HUMAN-Phosphothreonine232 relationship: transforms_into CCO:B0071306 ! TDIF2_HUMAN-Phosphoserine324 relationship: transforms_into CCO:B0071307 ! TDIF2_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0071308 ! TDIF2_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0071309 ! TDIF2_HUMAN-Phosphoserine528 relationship: transforms_into CCO:B0071310 ! TDIF2_HUMAN-Phosphoserine532 relationship: transforms_into CCO:B0071311 ! TDIF2_HUMAN-Phosphoserine533 relationship: transforms_into CCO:B0071312 ! TDIF2_HUMAN-Phosphoserine543 [Term] id: CCO:B0056527 name: Q5QJV5_HUMAN def: "DNA polymerase lamda2" [UniProtKB:Q5QJV5] xref: EMBL:AAQ74388.1 xref: UniProtKB:Q5QJV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0056528 name: Q5QPL4_HUMAN def: "Zinc finger protein 643" [UniProtKB:Q5QPL4] xref: EMBL:CAI19856.1 xref: UniProtKB:Q5QPL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020871 ! ZNF643_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056529 name: Q5QPV0_HUMAN def: "Recombining binding protein suppressor of hairless (Drosophila)-like (Recombining binding protein suppressor of hairless (Drosophila)-like, isoform CRA_b)" [UniProtKB:Q5QPV0] xref: EMBL:CAI21079.1 xref: EMBL:EAW75864.1 xref: UniProtKB:Q5QPV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021142 ! RBPSUHL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056530 name: Q5QPV1_HUMAN def: "Recombining binding protein suppressor of hairless (Drosophila)-like (Recombining binding protein suppressor of hairless (Drosophila)-like, isoform CRA_a)" [UniProtKB:Q5QPV1] xref: EMBL:CAI21078.1 xref: EMBL:EAW75863.1 xref: UniProtKB:Q5QPV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021142 ! RBPSUHL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056531 name: LRRK2_HUMAN def: "Leucine-rich repeat serine/threonine-protein kinase 2" [UniProtKB:Q5S007] synonym: "Dardarin" EXACT [UniProtKB:Q5S007] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q5S007] xref: EMBL:AAV63975.1 xref: EMBL:BAC87105.1 xref: EMBL:CAD39185.1 xref: UniProtKB:Q5S007 xref: UniProtKB:Q6ZS50 xref: UniProtKB:Q8NCX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018523 ! LRRK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001454 ! external side of mitochondrial outer membrane relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001432 ! positive regulation of protein ubiquitination relationship: participates_in CCO:P0002150 ! positive regulation of programmed cell death [Term] id: CCO:B0056532 name: Q5SPL1_HUMAN def: "Notch homolog 4 (Drosophila)" [UniProtKB:Q5SPL1] xref: EMBL:CAI18564.1 xref: EMBL:CAI41803.1 xref: UniProtKB:Q5SPL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008797 ! NOTCH4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0056533 name: Q5SQI6_HUMAN def: "Neuroepithelial cell transforming gene 1" [UniProtKB:Q5SQI6] xref: EMBL:CAI11032.1 xref: UniProtKB:Q5SQI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017018 ! NET1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056534 name: VAX1_HUMAN def: "Ventral anterior homeobox 1" [UniProtKB:Q5SQQ9] xref: EMBL:AAI01695.1 xref: EMBL:AAI01697.1 xref: EMBL:BAC86826.1 xref: EMBL:CAI14825.1 xref: UniProtKB:Q5SQQ9 xref: UniProtKB:Q6ZSX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020437 ! VAX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056535 name: Q5SRM8_HUMAN def: "Cell division cycle 40 homolog (S. cerevisiae)" [UniProtKB:Q5SRM8] xref: EMBL:CAI13324.1 xref: UniProtKB:Q5SRM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008012 ! CDC40_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0056536 name: Q5SSB9_HUMAN def: "Ficolin (Collagen/fibrinogen domain containing) 3 (Hakata antigen)" [UniProtKB:Q5SSB9] xref: EMBL:CAI14776.1 xref: UniProtKB:Q5SSB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017772 ! FCN3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056537 name: Q5ST39_HUMAN xref: UniProtKB:Q5ST39 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056538 name: Q5STG5_HUMAN def: "Notch homolog 4 (Drosophila)" [UniProtKB:Q5STG5] xref: EMBL:CAI17543.1 xref: UniProtKB:Q5STG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008797 ! NOTCH4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0056539 name: Q5SUJ6_HUMAN xref: UniProtKB:Q5SUJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056540 name: Q5SUJ7_HUMAN def: "Olfactory receptor, family 2, subfamily J, member 3" [UniProtKB:Q5SUJ7] xref: EMBL:CAI18102.1 xref: UniProtKB:Q5SUJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019102 ! OR2J3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056541 name: Q5SUK1_HUMAN def: "Olfactory receptor, family 2, subfamily H, member 2" [UniProtKB:Q5SUK1] xref: EMBL:AAI01684.1 xref: EMBL:CAI18013.1 xref: EMBL:CAI18602.1 xref: EMBL:CAQ09876.1 xref: EMBL:EAX03204.1 xref: UniProtKB:Q5SUK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019098 ! OR2H2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056542 name: Q5SUN7_HUMAN def: "Olfactory receptor, family 10, subfamily C, member 1" [UniProtKB:Q5SUN7] xref: EMBL:CAI18054.1 xref: EMBL:CAQ09887.1 xref: EMBL:CAQ10823.1 xref: UniProtKB:Q5SUN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018905 ! OR10C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056543 name: Q5SUN9_HUMAN def: "Olfactory receptor, family 12, subfamily D, member 2" [UniProtKB:Q5SUN9] xref: EMBL:CAI18051.1 xref: UniProtKB:Q5SUN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018938 ! OR12D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056544 name: Q5SVK9_HUMAN def: "Novel protein" [UniProtKB:Q5SVK9] xref: EMBL:CAI11008.1 xref: EMBL:CAI13196.1 xref: UniProtKB:Q5SVK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021143 ! RP11-114F7.3_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056545 name: ZBT41_HUMAN def: "Zinc finger and BTB domain-containing protein 41" [UniProtKB:Q5SVQ8] xref: EMBL:AAN71742.2 xref: EMBL:AAP97434.1 xref: EMBL:BAC87496.1 xref: EMBL:CAE45940.1 xref: EMBL:CAI13461.1 xref: EMBL:CAI14333.1 xref: UniProtKB:Q5SVQ8 xref: UniProtKB:Q6MZT8 xref: UniProtKB:Q6ZR25 xref: UniProtKB:Q7Z4T1 xref: UniProtKB:Q8IZ99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020557 ! ZBTB41_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056546 name: Q5SW06_HUMAN xref: UniProtKB:Q5SW06 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056547 name: ARH_HUMAN def: "Low density lipoprotein receptor adapter protein 1" [UniProtKB:Q5SW96] synonym: "Autosomal recessive hypercholesterolemia protein" EXACT [UniProtKB:Q5SW96] xref: EMBL:AAH29770.2 xref: EMBL:AAQ90407.1 xref: EMBL:CAB56030.2 xref: EMBL:CAI16483.1 xref: EMBL:CAM12863.1 xref: UniProtKB:A2BHI5 xref: UniProtKB:Q5SW96 xref: UniProtKB:Q6TQS9 xref: UniProtKB:Q8N2Y0 xref: UniProtKB:Q9UFI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017026 ! LDLRAP1_human relationship: has_function CCO:F0000213 ! phosphotyrosine binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0002868 ! transport accessory protein activity relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_function CCO:F0004372 ! clathrin binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000966 ! AP-1 adaptor complex relationship: located_in CCO:C0000967 ! AP-2 adaptor complex relationship: participates_in CCO:I0015365 ! ap2b1-ldlrap1 physical interaction relationship: participates_in CCO:P0002802 ! positive regulation of receptor-mediated endocytosis relationship: transforms_into CCO:B0063569 ! ARH_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0063570 ! ARH_HUMAN-Phosphoserine186 [Term] id: CCO:B0056548 name: PR15B_HUMAN def: "Protein phosphatase 1 regulatory subunit 15B" [UniProtKB:Q5SWA1] xref: EMBL:AAH65280.1 xref: EMBL:BAB55266.1 xref: EMBL:BAD96597.1 xref: EMBL:CAH56240.1 xref: EMBL:CAI16570.1 xref: UniProtKB:Q53GQ4 xref: UniProtKB:Q5SWA1 xref: UniProtKB:Q658M2 xref: UniProtKB:Q6P156 xref: UniProtKB:Q96SN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019485 ! PPP1R15B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0056549 name: ZN678_HUMAN def: "Zinc finger protein 678" [UniProtKB:Q5SXM1] xref: EMBL:AAH42500.1 xref: EMBL:CAI21826.1 xref: UniProtKB:Q5SXM1 xref: UniProtKB:Q8IVQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020893 ! ZNF678_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056550 name: SNPC4_HUMAN def: "snRNA-activating protein complex subunit 4" [UniProtKB:Q5SXM2] synonym: "Proximal sequence element-binding transcription factor subunit alpha" EXACT [UniProtKB:Q5SXM2] synonym: "PSE-binding factor subunit alpha" EXACT [UniProtKB:Q5SXM2] synonym: "PTF subunit alpha" EXACT [UniProtKB:Q5SXM2] synonym: "SNAPc 190 kDa subunit" EXACT [UniProtKB:Q5SXM2] synonym: "SNAPc subunit 4" EXACT [UniProtKB:Q5SXM2] synonym: "snRNA-activating protein complex 190 kDa subunit" EXACT [UniProtKB:Q5SXM2] xref: EMBL:AAC02972.1 xref: EMBL:CAI13935.1 xref: UniProtKB:Q5SXM2 xref: UniProtKB:Q9Y6P7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019967 ! SNAPC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070694 ! SNPC4_HUMAN-Phosphothreonine1157 relationship: transforms_into CCO:B0070695 ! SNPC4_HUMAN-Phosphoserine1224 [Term] id: CCO:B0056551 name: Q5SY18_HUMAN def: "Pleckstrin homology domain containing, family G (With RhoGef domain) member 5" [UniProtKB:Q5SY18] xref: EMBL:CAI16068.1 xref: EMBL:CAI22160.1 xref: UniProtKB:Q5SY18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019417 ! PLEKHG5_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056552 name: Q5SYV3_HUMAN xref: UniProtKB:Q5SYV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056553 name: Z322B_HUMAN def: "Zinc finger protein 322B" [UniProtKB:Q5SYY0] xref: EMBL:CAI14725.2 xref: UniProtKB:Q5SYY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020520 ! ZNF322B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056554 name: Q5SZL4_HUMAN def: "TBC1 domain family, member 7" [UniProtKB:Q5SZL4] xref: EMBL:CAI21572.1 xref: UniProtKB:Q5SZL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020182 ! TBC1D7_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056555 name: Q5SZL5_HUMAN def: "TBC1 domain family, member 7" [UniProtKB:Q5SZL5] xref: EMBL:CAI21571.1 xref: UniProtKB:Q5SZL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020182 ! TBC1D7_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056556 name: Q5SZL8_HUMAN def: "TBC1 domain family, member 7" [UniProtKB:Q5SZL8] xref: EMBL:CAI21574.1 xref: UniProtKB:Q5SZL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020182 ! TBC1D7_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056557 name: Q5SZM1_HUMAN def: "TBC1 domain family, member 7" [UniProtKB:Q5SZM1] xref: EMBL:CAI21576.1 xref: UniProtKB:Q5SZM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020182 ! TBC1D7_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056558 name: Q5SZM2_HUMAN def: "TBC1 domain family, member 7" [UniProtKB:Q5SZM2] xref: EMBL:CAI21575.1 xref: UniProtKB:Q5SZM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020182 ! TBC1D7_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056559 name: Q5SZP2_HUMAN def: "Paired box gene 2 (Paired box gene 2, isoform CRA_e)" [UniProtKB:Q5SZP2] xref: EMBL:CAH70952.1 xref: EMBL:CAI17856.1 xref: EMBL:EAW49813.1 xref: UniProtKB:Q5SZP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019306 ! PAX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056560 name: Q5SZP3_HUMAN def: "Paired box gene 2 (Paired box gene 2, isoform CRA_d)" [UniProtKB:Q5SZP3] xref: EMBL:CAH70951.1 xref: EMBL:CAI17855.1 xref: EMBL:EAW49812.1 xref: UniProtKB:Q5SZP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019306 ! PAX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056561 name: Q5SZP4_HUMAN def: "Zinc finger protein 510" [UniProtKB:Q5SZP4] xref: EMBL:CAI15267.1 xref: UniProtKB:Q5SZP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020788 ! ZNF510_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056562 name: ZN362_HUMAN def: "Zinc finger protein 362" [UniProtKB:Q5T0B9] xref: EMBL:AAI04780.1 xref: EMBL:AAI12114.1 xref: EMBL:AAL55863.1 xref: EMBL:CAI13953.1 xref: EMBL:EAX07464.1 xref: UniProtKB:Q5T0B9 xref: UniProtKB:Q8WYU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020719 ! ZNF362_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056563 name: Q5T1N8_HUMAN def: "G-protein signaling modulator 2 (AGS3-like, C. elegans) (G-protein signalling modulator 2 (AGS3-like, C. elegans), isoform CRA_a)" [UniProtKB:Q5T1N8] xref: EMBL:CAI14361.1 xref: EMBL:EAW56340.1 xref: UniProtKB:Q5T1N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004724 ! GPSM2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056564 name: ZEP3_HUMAN def: "Transcription factor HIVEP3" [UniProtKB:Q5T1R4] synonym: "Human immunodeficiency virus type I enhancer-binding protein 3" EXACT [UniProtKB:Q5T1R4] synonym: "Kappa-B and V(D)J recombination signal sequences-binding protein" EXACT [UniProtKB:Q5T1R4] synonym: "Kappa-binding protein 1" EXACT [UniProtKB:Q5T1R4] synonym: "KBP-1" EXACT [UniProtKB:Q5T1R4] synonym: "Zinc finger protein ZAS3" EXACT [UniProtKB:Q5T1R4] xref: EMBL:AAI52564.1 xref: EMBL:AAK01082.1 xref: EMBL:BAB13381.2 xref: EMBL:CAI14537.1 xref: EMBL:CAI14538.1 xref: UniProtKB:A7YY91 xref: UniProtKB:Q5T1R4 xref: UniProtKB:Q5T1R5 xref: UniProtKB:Q9BZS0 xref: UniProtKB:Q9HCL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020579 ! HIVEP3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0071997 ! ZEP3_HUMAN-Phosphothreonine2037 [Term] id: CCO:B0056565 name: UTF1_HUMAN def: "Undifferentiated embryonic cell transcription factor 1" [UniProtKB:Q5T230] xref: EMBL:AAT38949.1 xref: EMBL:BAA33463.1 xref: EMBL:CAI17342.1 xref: UniProtKB:O75833 xref: UniProtKB:Q5T230 xref: UniProtKB:Q6J1H3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020425 ! UTF1_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0056566 name: CTLF7_HUMAN def: "Centaurin-gamma-like family member 7" [UniProtKB:Q5T2P9] xref: EMBL:CAI12206.1 xref: UniProtKB:Q5T2P9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017491 ! CTGLF7_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0056567 name: Q5T382_HUMAN def: "Dopamine beta-hydroxylase (Dopamine beta-monooxygenase)" [UniProtKB:Q5T382] xref: EMBL:CAI13353.1 xref: UniProtKB:Q5T382 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017605 ! DBH_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0000897 ! dopamine beta-monooxygenase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000887 ! cellular process [Term] id: CCO:B0056568 name: Q5T3H4_HUMAN def: "Regulator of G-protein signaling 7 (Regulator of G-protein signalling 7, isoform CRA_a)" [UniProtKB:Q5T3H4] xref: EMBL:CAH71987.1 xref: EMBL:CAH73810.1 xref: EMBL:CAI15140.1 xref: EMBL:CAI16818.1 xref: EMBL:EAW70086.1 xref: UniProtKB:Q5T3H4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019705 ! RGS7_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056569 name: Q5T3H5_HUMAN def: "Regulator of G-protein signaling 7" [UniProtKB:Q5T3H5] xref: EMBL:CAI16824.1 xref: UniProtKB:Q5T3H5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019705 ! RGS7_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056570 name: Q5T3S6_HUMAN def: "RAP1 GTPase activating protein" [UniProtKB:Q5T3S6] xref: EMBL:CAI16258.1 xref: UniProtKB:Q5T3S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0056571 name: Q5T3S7_HUMAN def: "RAP1 GTPase activating protein" [UniProtKB:Q5T3S7] xref: EMBL:CAI16257.1 xref: UniProtKB:Q5T3S7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056572 name: Q5T3S9_HUMAN def: "RAP1 GTPase activating protein" [UniProtKB:Q5T3S9] xref: EMBL:CAI16255.1 xref: UniProtKB:Q5T3S9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0056573 name: Q5T3T0_HUMAN def: "RAP1 GTPase activating protein" [UniProtKB:Q5T3T0] xref: EMBL:CAI16254.1 xref: UniProtKB:Q5T3T0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056574 name: Q5T3T1_HUMAN def: "RAP1 GTPase activating protein" [UniProtKB:Q5T3T1] xref: EMBL:CAI16253.1 xref: UniProtKB:Q5T3T1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019790 ! RAP1GAP_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056575 name: SFRP5_HUMAN def: "Secreted frizzled-related protein 5 precursor" [UniProtKB:Q5T4F7] synonym: "Frizzled-related protein 1b" EXACT [UniProtKB:Q5T4F7] synonym: "FRP-1b" EXACT [UniProtKB:Q5T4F7] synonym: "SARP-3" EXACT [UniProtKB:Q5T4F7] synonym: "Secreted apoptosis-related protein 3" EXACT [UniProtKB:Q5T4F7] synonym: "sFRP-5" EXACT [UniProtKB:Q5T4F7] xref: EMBL:AAB70794.1 xref: EMBL:AAD25052.1 xref: EMBL:AAH50435.2 xref: EMBL:CAI14274.1 xref: UniProtKB:O14780 xref: UniProtKB:Q5T4F7 xref: UniProtKB:Q86TH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019877 ! SFRP5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056576 name: Q5T4L0_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q5T4L0] xref: EMBL:BAG65440.1 xref: EMBL:CAI14026.1 xref: EMBL:EAW53251.1 xref: UniProtKB:Q5T4L0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017449 ! CREB3L4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056577 name: Q5T4L1_HUMAN def: "cAMP responsive element binding protein 3-like 4" [UniProtKB:Q5T4L1] xref: EMBL:CAI14025.1 xref: UniProtKB:Q5T4L1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017449 ! CREB3L4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056578 name: ARTN_HUMAN def: "Artemin precursor" [UniProtKB:Q5T4W7] synonym: "Enovin" EXACT [UniProtKB:Q5T4W7] synonym: "Neublastin" EXACT [UniProtKB:Q5T4W7] xref: EMBL:AAC98690.1 xref: EMBL:AAD13109.1 xref: EMBL:AAD13110.1 xref: EMBL:AAD21075.1 xref: EMBL:AAH62375.1 xref: EMBL:CAB52396.1 xref: EMBL:CAI16797.1 xref: UniProtKB:O95441 xref: UniProtKB:O96030 xref: UniProtKB:Q5T4W7 xref: UniProtKB:Q6P6A3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017053 ! ARTN_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000793 ! neuroblast proliferation [Term] id: CCO:B0056579 name: Q5T4Y8_HUMAN def: "Membrane associated guanylate kinase, WW and PDZ domain containing 1" [UniProtKB:Q5T4Y8] xref: EMBL:CAI14543.1 xref: UniProtKB:Q5T4Y8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018559 ! MAGI1_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0056580 name: ZN684_HUMAN def: "Zinc finger protein 684" [UniProtKB:Q5T5D7] xref: EMBL:AAH91518.1 xref: EMBL:AAI11464.1 xref: EMBL:CAI22134.1 xref: UniProtKB:Q2NKY4 xref: UniProtKB:Q5T5D7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020897 ! ZNF684_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056581 name: Q5T5D8_HUMAN def: "Zinc finger protein 684" [UniProtKB:Q5T5D8] xref: EMBL:CAI22133.1 xref: UniProtKB:Q5T5D8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020897 ! ZNF684_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056582 name: Q5T5D9_HUMAN def: "Zinc finger protein 684" [UniProtKB:Q5T5D9] xref: EMBL:CAI22132.1 xref: UniProtKB:Q5T5D9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020897 ! ZNF684_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056583 name: Q5T5H8_HUMAN def: "Estrogen receptor 1" [UniProtKB:Q5T5H8] xref: EMBL:CAI21011.2 xref: UniProtKB:Q5T5H8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004590 ! ESR1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056584 name: RHG21_HUMAN def: "Rho GTPase-activating protein 21" [UniProtKB:Q5T5U3] synonym: "Rho GTPase-activating protein 10" EXACT [UniProtKB:Q5T5U3] synonym: "Rho-type GTPase-activating protein 21" EXACT [UniProtKB:Q5T5U3] xref: EMBL:AAH22931.1 xref: EMBL:AAM22955.1 xref: EMBL:BAA92662.2 xref: EMBL:CAD39153.1 xref: EMBL:CAD97787.1 xref: EMBL:CAI14323.1 xref: EMBL:CAI40176.1 xref: UniProtKB:Q0VF98 xref: UniProtKB:Q5T5U3 xref: UniProtKB:Q7Z3P7 xref: UniProtKB:Q8N3A2 xref: UniProtKB:Q8NI19 xref: UniProtKB:Q8TBV5 xref: UniProtKB:Q9P2C3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019721 ! ARHGAP21_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069956 ! RHG21_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: transforms_into CCO:B0069958 ! RHG21_HUMAN-Phosphoserine474 relationship: transforms_into CCO:B0069959 ! RHG21_HUMAN-Phosphoserine476 relationship: transforms_into CCO:B0069960 ! RHG21_HUMAN-Phosphoserine923 relationship: transforms_into CCO:B0069961 ! RHG21_HUMAN-Phosphoserine1089 relationship: transforms_into CCO:B0069962 ! RHG21_HUMAN-Phosphoserine1098 relationship: transforms_into CCO:B0069963 ! RHG21_HUMAN-Phosphoserine1219 relationship: transforms_into CCO:B0069964 ! RHG21_HUMAN-Phosphoserine1220 relationship: transforms_into CCO:B0069965 ! RHG21_HUMAN-Phosphotyrosine1239 relationship: transforms_into CCO:B0069966 ! RHG21_HUMAN-Phosphothreonine1282 relationship: transforms_into CCO:B0069967 ! RHG21_HUMAN-Phosphoserine1377 relationship: transforms_into CCO:B0069968 ! RHG21_HUMAN-Phosphoserine1382 relationship: transforms_into CCO:B0069969 ! RHG21_HUMAN-Phosphoserine1430 relationship: transforms_into CCO:B0069970 ! RHG21_HUMAN-Phosphoserine1431 relationship: transforms_into CCO:B0069971 ! RHG21_HUMAN-Phosphoserine1432 relationship: transforms_into CCO:B0069972 ! RHG21_HUMAN-Phosphoserine1526 relationship: transforms_into CCO:B0069973 ! RHG21_HUMAN-Phosphoserine1668 [Term] id: CCO:B0056585 name: Q5T5Y4_HUMAN def: "Adrenergic, beta-1-, receptor" [UniProtKB:Q5T5Y4] xref: EMBL:CAI16920.1 xref: UniProtKB:Q5T5Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016923 ! ADRB1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001282 ! beta1-adrenergic receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056586 name: GP110_HUMAN def: "Probable G-protein coupled receptor 110 precursor" [UniProtKB:Q5T601] synonym: "G-protein coupled receptor KPG_012" EXACT [UniProtKB:Q5T601] synonym: "G-protein coupled receptor PGR19" EXACT [UniProtKB:Q5T601] xref: EMBL:AAN46666.1 xref: EMBL:AAO85107.1 xref: EMBL:BAB70874.1 xref: EMBL:BAC45260.1 xref: EMBL:BAD83599.1 xref: EMBL:CAI13873.1 xref: EMBL:CAI13874.1 xref: UniProtKB:Q5KU15 xref: UniProtKB:Q5T5Z9 xref: UniProtKB:Q5T601 xref: UniProtKB:Q86SM1 xref: UniProtKB:Q8IXE3 xref: UniProtKB:Q8IZF8 xref: UniProtKB:Q96DQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017954 ! GPR110_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056587 name: ZN648_HUMAN def: "Zinc finger protein 648" [UniProtKB:Q5T619] xref: EMBL:CAI15305.1 xref: UniProtKB:Q5T619 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020873 ! ZNF648_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072205 ! ZN648_HUMAN-Phosphoserine461 [Term] id: CCO:B0056588 name: Q5T6F6_HUMAN def: "Nuclear receptor subfamily 5, group A, member 1" [UniProtKB:Q5T6F6] xref: EMBL:CAI10958.1 xref: UniProtKB:Q5T6F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020068 ! NR5A1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056589 name: Q5T6F7_HUMAN def: "Nuclear receptor subfamily 5, group A, member 1" [UniProtKB:Q5T6F7] xref: EMBL:CAI10871.1 xref: EMBL:CAI10957.1 xref: UniProtKB:Q5T6F7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020068 ! NR5A1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056590 name: Q5T6H8_HUMAN def: "Early B-cell factor 3" [UniProtKB:Q5T6H8] xref: EMBL:CAI12791.1 xref: UniProtKB:Q5T6H8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017428 ! EBF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056591 name: PHF19_HUMAN def: "PHD finger protein 19" [UniProtKB:Q5T6S3] synonym: "hPCL3" EXACT [UniProtKB:Q5T6S3] synonym: "Polycomb-like protein 3" EXACT [UniProtKB:Q5T6S3] xref: EMBL:AAH22374.1 xref: EMBL:AAI08664.1 xref: EMBL:AAI25077.1 xref: EMBL:AAI25078.1 xref: EMBL:CAB55950.1 xref: EMBL:CAE45832.1 xref: EMBL:CAI15690.1 xref: EMBL:CAI15691.1 xref: EMBL:CAI15692.1 xref: EMBL:CAI95112.1 xref: UniProtKB:Q32NF2 xref: UniProtKB:Q5T6S3 xref: UniProtKB:Q5T6S4 xref: UniProtKB:Q6N038 xref: UniProtKB:Q8TBL6 xref: UniProtKB:Q9UFS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019379 ! PHF19_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056592 name: GPC6A_HUMAN def: "G-protein coupled receptor family C group 6 member A precursor" [UniProtKB:Q5T6X5] synonym: "G-protein coupled receptor 33" EXACT [UniProtKB:Q5T6X5] synonym: "hGPCR33" EXACT [UniProtKB:Q5T6X5] synonym: "hGPRC6A" EXACT [UniProtKB:Q5T6X5] xref: EMBL:AAM22230.1 xref: EMBL:AAS13465.1 xref: EMBL:AAS13466.1 xref: EMBL:AAS13467.1 xref: EMBL:BAB89328.1 xref: EMBL:BAC05904.1 xref: EMBL:CAI16922.1 xref: UniProtKB:Q5T6X5 xref: UniProtKB:Q6JK43 xref: UniProtKB:Q6JK44 xref: UniProtKB:Q8NGU8 xref: UniProtKB:Q8NHZ9 xref: UniProtKB:Q8TDT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017999 ! GPRC6A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056593 name: Q5T7A0_HUMAN def: "CDC42 binding protein kinase alpha (DMPK-like)" [UniProtKB:Q5T7A0] xref: EMBL:CAI19111.1 xref: UniProtKB:Q5T7A0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018651 ! CDC42BPA_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056594 name: Q5T7S7_HUMAN def: "LIM homeobox 6" [UniProtKB:Q5T7S7] synonym: "LIM homeobox 6, isoform CRA_a" EXACT [UniProtKB:Q5T7S7] xref: EMBL:AAI03937.1 xref: EMBL:CAI14704.1 xref: EMBL:EAW87515.1 xref: UniProtKB:Q5T7S7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018489 ! LHX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056595 name: ZN618_HUMAN def: "Zinc finger protein 618" [UniProtKB:Q5T7W0] xref: EMBL:AAH12922.1 xref: EMBL:AAH36039.1 xref: EMBL:AAH53892.1 xref: EMBL:BAB85538.1 xref: EMBL:BAC86741.1 xref: EMBL:CAI15242.1 xref: EMBL:CAI15243.1 xref: EMBL:CAI15897.1 xref: EMBL:CAI15898.1 xref: UniProtKB:Q4G0X6 xref: UniProtKB:Q5T7W0 xref: UniProtKB:Q5T7W1 xref: UniProtKB:Q6ZT53 xref: UniProtKB:Q7Z6B9 xref: UniProtKB:Q8TF49 xref: UniProtKB:Q96E49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020858 ! ZNF618_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072185 ! ZN618_HUMAN-Phosphoserine16 [Term] id: CCO:B0056596 name: GP158_HUMAN def: "Probable G-protein coupled receptor 158 precursor" [UniProtKB:Q5T848] xref: EMBL:AAS18315.1 xref: EMBL:BAA86450.2 xref: EMBL:CAI15725.1 xref: EMBL:CAI16106.1 xref: EMBL:CAI16833.1 xref: UniProtKB:Q5T848 xref: UniProtKB:Q6QR81 xref: UniProtKB:Q9ULT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017981 ! GPR158_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066529 ! GP158_HUMAN-Phosphoserine904 [Term] id: CCO:B0056597 name: Q5T980_HUMAN def: "Scm-like with four mbt domains 2" [UniProtKB:Q5T980] xref: EMBL:CAI18943.1 xref: EMBL:CAI19141.1 xref: UniProtKB:Q5T980 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019947 ! SFMBT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056598 name: Q5T981_HUMAN def: "Scm-like with four mbt domains 2" [UniProtKB:Q5T981] xref: EMBL:CAI18942.1 xref: EMBL:CAI19140.1 xref: UniProtKB:Q5T981 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019947 ! SFMBT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056599 name: Q5T9H8_HUMAN def: "cAMP responsive element modulator" [UniProtKB:Q5T9H8] xref: EMBL:CAI12142.1 xref: UniProtKB:Q5T9H8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017453 ! CREM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056600 name: Q5T9I5_HUMAN def: "cAMP responsive element modulator" [UniProtKB:Q5T9I5] xref: EMBL:CAI12146.1 xref: UniProtKB:Q5T9I5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017453 ! CREM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056601 name: GP177_HUMAN def: "Integral membrane protein GPR177 precursor" [UniProtKB:Q5T9L3] synonym: "EVI" EXACT [UniProtKB:Q5T9L3] synonym: "Protein evenness interrupted homolog" EXACT [UniProtKB:Q5T9L3] synonym: "Protein wntless homolog" EXACT [UniProtKB:Q5T9L3] synonym: "Putative NFkB-activating protein 373" EXACT [UniProtKB:Q5T9L3] xref: EMBL:AAI10827.1 xref: EMBL:AAQ89394.1 xref: EMBL:ABD58927.1 xref: EMBL:BAC11333.1 xref: EMBL:CAD98094.1 xref: EMBL:CAI15024.1 xref: EMBL:CAI15027.1 xref: EMBL:CAI21993.1 xref: UniProtKB:Q5T9L3 xref: UniProtKB:Q7Z2Z9 xref: UniProtKB:Q8NC43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017989 ! GPR177_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0056602 name: Q5T9U4_HUMAN def: "Myocyte enhancer factor 2D" [UniProtKB:Q5T9U4] xref: EMBL:CAI17186.1 xref: UniProtKB:Q5T9U4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018602 ! MEF2D_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056603 name: HES5_HUMAN def: "Transcription factor HES-5" [UniProtKB:Q5TA89] synonym: "Hairy and enhancer of split 5" EXACT [UniProtKB:Q5TA89] xref: EMBL:ABB83829.1 xref: EMBL:CAI20411.1 xref: UniProtKB:Q5TA89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018121 ! HES5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation [Term] id: CCO:B0056604 name: DEP1A_HUMAN def: "DEP domain-containing protein 1A" [UniProtKB:Q5TB30] xref: EMBL:AAH03511.1 xref: EMBL:AAH65304.1 xref: EMBL:BAA91201.1 xref: EMBL:BAB14246.1 xref: EMBL:BAF91373.1 xref: EMBL:BAF91374.1 xref: EMBL:CAB92444.1 xref: EMBL:CAI22441.1 xref: EMBL:CAI22442.1 xref: EMBL:CAI22443.1 xref: EMBL:EAX06475.1 xref: EMBL:EAX06476.1 xref: UniProtKB:A8QXE0 xref: UniProtKB:A8QXE1 xref: UniProtKB:Q05DU3 xref: UniProtKB:Q5TB28 xref: UniProtKB:Q5TB30 xref: UniProtKB:Q9H9I3 xref: UniProtKB:Q9NX21 xref: UniProtKB:Q9NXZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017553 ! DEPDC1A_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064739 ! DEP1A_HUMAN-Phosphoserine512 [Term] id: CCO:B0056605 name: FRY_HUMAN def: "Protein furry homolog" [UniProtKB:Q5TBA9] xref: EMBL:CAB42442.1 xref: EMBL:CAI12629.1 xref: EMBL:CAI13379.1 xref: EMBL:CAI40478.1 xref: UniProtKB:Q5TBA9 xref: UniProtKB:Q9Y3N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017837 ! FRY_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066283 ! FRY_HUMAN-Phosphothreonine951 relationship: transforms_into CCO:B0066284 ! FRY_HUMAN-Phosphotyrosine954 [Term] id: CCO:B0056606 name: Q5TBP5_HUMAN def: "TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa" [UniProtKB:Q5TBP5] xref: EMBL:CAI11046.1 xref: EMBL:CAI19183.1 xref: UniProtKB:Q5TBP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020136 ! TAF4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056607 name: Q5TBQ6_HUMAN def: "TBC1 domain family, member 2 (TBC1 domain family, member 2, isoform CRA_d)" [UniProtKB:Q5TBQ6] xref: EMBL:CAH71886.1 xref: EMBL:CAI12579.1 xref: EMBL:CAI13884.1 xref: EMBL:EAW58885.1 xref: UniProtKB:Q5TBQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020186 ! TBC1D2_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056608 name: Q5TBQ7_HUMAN def: "TBC1 domain family, member 2 (TBC1 domain family, member 2, isoform CRA_e)" [UniProtKB:Q5TBQ7] xref: EMBL:CAH71884.1 xref: EMBL:CAI13883.1 xref: EMBL:EAW58886.1 xref: UniProtKB:Q5TBQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020186 ! TBC1D2_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056609 name: GRTP1_HUMAN def: "Growth hormone-regulated TBC protein 1" [UniProtKB:Q5TC63] synonym: "TBC1 domain family member 6" EXACT [UniProtKB:Q5TC63] xref: EMBL:AAH33071.2 xref: EMBL:AAH62461.1 xref: EMBL:AAH80640.1 xref: EMBL:AAI12124.1 xref: EMBL:AAI12126.1 xref: EMBL:BAB15368.1 xref: EMBL:CAI13799.2 xref: EMBL:CAI13800.2 xref: UniProtKB:Q2M232 xref: UniProtKB:Q5TC63 xref: UniProtKB:Q5TC64 xref: UniProtKB:Q66K26 xref: UniProtKB:Q6P659 xref: UniProtKB:Q8N528 xref: UniProtKB:Q9H695 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018081 ! GRTP1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056610 name: ZBT37_HUMAN def: "Zinc finger and BTB domain-containing protein 37" [UniProtKB:Q5TC79] xref: EMBL:AAH03116.1 xref: EMBL:AAH06315.1 xref: EMBL:BAB71422.1 xref: EMBL:CAI19420.1 xref: EMBL:CAI19421.1 xref: EMBL:CAI19422.1 xref: UniProtKB:Q5TC79 xref: UniProtKB:Q5TC80 xref: UniProtKB:Q96M87 xref: UniProtKB:Q9BQ88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020554 ! ZBTB37_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056611 name: ZN697_HUMAN def: "Zinc finger protein 697" [UniProtKB:Q5TEC3] xref: EMBL:AAH07260.1 xref: EMBL:CAI21950.1 xref: UniProtKB:Q5TEC3 xref: UniProtKB:Q96IT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020904 ! ZNF697_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056612 name: Q5TEG9_HUMAN def: "Zinc finger protein 436 (Putative uncharacterized protein ZNF436)" [UniProtKB:Q5TEG9] xref: EMBL:CAI19028.1 xref: UniProtKB:A6NEV7 xref: UniProtKB:Q5TEG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020749 ! ZNF436_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056613 name: Q5TEH8_HUMAN def: "Protein Wnt" [UniProtKB:Q5TEH8] xref: EMBL:CAI22311.1 xref: EMBL:CAI22710.1 xref: UniProtKB:Q5TEH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020485 ! WNT2B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056614 name: Q5TEK5_HUMAN def: "Phosphodiesterase 4B, cAMP-specific (Phosphodiesterase E4 dunce homolog, Drosophila) (Phosphodiesterase 4B, cAMP-specific (Phosphodiesterase E4 dunce homolog, Drosophila), isoform CRA_a)" [UniProtKB:Q5TEK5] xref: EMBL:CAI21750.1 xref: EMBL:CAI23100.1 xref: EMBL:EAX06524.1 xref: UniProtKB:Q5TEK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019339 ! PDE4B_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056615 name: Q5TEV0_HUMAN def: "Rho guanine nucleotide exchange factor (GEF) 19" [UniProtKB:Q5TEV0] xref: EMBL:CAI22569.1 xref: UniProtKB:Q5TEV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017025 ! ARHGEF19_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056616 name: Q5TEV1_HUMAN def: "Rho guanine nucleotide exchange factor (GEF) 19" [UniProtKB:Q5TEV1] xref: EMBL:CAI22568.1 xref: UniProtKB:Q5TEV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017025 ! ARHGEF19_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056617 name: Q5TEV6_HUMAN def: "Chromosome 1 open reading frame 89" [UniProtKB:Q5TEV6] xref: EMBL:CAI22563.1 xref: UniProtKB:Q5TEV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017201 ! C1orf89_human relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056618 name: Q5TF93_HUMAN def: "Hairy/enhancer-of-split related with YRPW motif 2" [UniProtKB:Q5TF93] xref: EMBL:CAI20068.1 xref: UniProtKB:Q5TF93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018127 ! HEY2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056619 name: RG18L_HUMAN def: "Rho GTPase-activating protein 18-like" [UniProtKB:Q5TG30] xref: EMBL:CAI19168.2 xref: UniProtKB:Q5TG30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008392 ! C20orf95_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056620 name: Q5TG39_HUMAN def: "DNA methyltransferase 1 associated protein 1" [UniProtKB:Q5TG39] xref: EMBL:CAI23199.1 xref: UniProtKB:Q5TG39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004483 ! DMAP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0056621 name: Q5TG40_HUMAN def: "DNA methyltransferase 1 associated protein 1" [UniProtKB:Q5TG40] xref: EMBL:CAI23198.1 xref: UniProtKB:Q5TG40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004483 ! DMAP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0056622 name: Q5TG85_HUMAN def: "Chromodomain helicase DNA binding protein 5" [UniProtKB:Q5TG85] xref: EMBL:CAI19883.1 xref: UniProtKB:Q5TG85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017350 ! CHD5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056623 name: Q5TGE8_HUMAN def: "Core-binding factor, runt domain, alpha subunit 2; translocated to, 2" [UniProtKB:Q5TGE8] xref: EMBL:CAI13422.1 xref: EMBL:CAI19278.1 xref: UniProtKB:Q5TGE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018678 ! CBFA2T2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056624 name: Q5TGK2_HUMAN xref: UniProtKB:Q5TGK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056625 name: HES3_HUMAN def: "Transcription factor HES-3" [UniProtKB:Q5TGS1] synonym: "Hairy and enhancer of split 3" EXACT [UniProtKB:Q5TGS1] xref: EMBL:CAI19439.1 xref: UniProtKB:Q5TGS0 xref: UniProtKB:Q5TGS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018119 ! HES3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056626 name: BIG3_HUMAN def: "Brefeldin A-inhibited guanine nucleotide-exchange protein 3" [UniProtKB:Q5TH69] xref: EMBL:AAH14227.2 xref: EMBL:AAH33191.1 xref: EMBL:AAL04174.1 xref: EMBL:BAA86558.2 xref: EMBL:CAI19661.3 xref: EMBL:CAM28242.2 xref: EMBL:CAM28244.2 xref: UniProtKB:Q5TH69 xref: UniProtKB:Q76MU8 xref: UniProtKB:Q8N4Y4 xref: UniProtKB:Q96CH9 xref: UniProtKB:Q96P46 xref: UniProtKB:Q9ULH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017156 ! ARFGEF3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0063923 ! BIG3_HUMAN-Phosphoserine1651 [Term] id: CCO:B0056627 name: Q5THJ1_HUMAN def: "PR domain containing 2, with ZNF domain" [UniProtKB:Q5THJ1] xref: EMBL:CAB37643.1 xref: UniProtKB:Q5THJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019494 ! PRDM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056628 name: EFCB6_HUMAN def: "EF-hand calcium-binding domain-containing protein 6" [UniProtKB:Q5THR3] synonym: "CAP-binding protein complex-interacting protein 1" EXACT [UniProtKB:Q5THR3] synonym: "DJ-1-binding protein" EXACT [UniProtKB:Q5THR3] synonym: "DJBP" EXACT [UniProtKB:Q5THR3] xref: EMBL:AAH39315.1 xref: EMBL:BAB15703.1 xref: EMBL:BAB33342.1 xref: EMBL:BAB71780.1 xref: EMBL:BAF85100.1 xref: EMBL:BAF85187.1 xref: EMBL:CAB91065.1 xref: EMBL:CAQ07046.1 xref: EMBL:CAQ07047.1 xref: EMBL:CAQ09926.1 xref: EMBL:CAQ09928.1 xref: EMBL:CAQ10020.1 xref: EMBL:CAQ10022.1 xref: EMBL:CAQ10334.1 xref: EMBL:CAQ11050.1 xref: UniProtKB:A8K8P6 xref: UniProtKB:A8K8Y3 xref: UniProtKB:B0QYI4 xref: UniProtKB:B0QYI6 xref: UniProtKB:Q5THR3 xref: UniProtKB:Q5U5T6 xref: UniProtKB:Q9BY88 xref: UniProtKB:Q9H5C4 xref: UniProtKB:Q9NSF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017662 ! EFCAB6_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056629 name: Q5TIG5_HUMAN def: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 4" [UniProtKB:Q5TIG5] xref: EMBL:CAI20901.1 xref: EMBL:CAI40825.1 xref: EMBL:CAI42813.1 xref: UniProtKB:Q5TIG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004036 ! MLLT4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056630 name: Q5TIG7_HUMAN def: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 4 (Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 4, isoform CRA_c)" [UniProtKB:Q5TIG7] xref: EMBL:CAI20902.1 xref: EMBL:CAI40826.1 xref: EMBL:CAI42814.1 xref: EMBL:EAW47482.1 xref: UniProtKB:Q5TIG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004036 ! MLLT4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056631 name: Q5TIH0_HUMAN def: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 4" [UniProtKB:Q5TIH0] xref: EMBL:CAI20904.1 xref: EMBL:CAI40828.1 xref: UniProtKB:Q5TIH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004036 ! MLLT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056632 name: Q5TIH1_HUMAN def: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 4" [UniProtKB:Q5TIH1] xref: EMBL:CAI20903.1 xref: EMBL:CAI40827.1 xref: UniProtKB:Q5TIH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004036 ! MLLT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056633 name: Q5TIH6_HUMAN def: "T-box 19" [UniProtKB:Q5TIH6] xref: EMBL:CAI22639.1 xref: UniProtKB:Q5TIH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020193 ! TBX19_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056634 name: Q5TIH7_HUMAN def: "T-box 19" [UniProtKB:Q5TIH7] xref: EMBL:CAI22638.1 xref: UniProtKB:Q5TIH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020193 ! TBX19_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056635 name: Q5TIJ2_HUMAN def: "Pogo transposable element with KRAB domain" [UniProtKB:Q5TIJ2] xref: EMBL:CAI23579.1 xref: UniProtKB:Q5TIJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019466 ! POGK_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056636 name: ZN658_HUMAN def: "Zinc finger protein 658" [UniProtKB:Q5TYW1] xref: EMBL:AAH31626.1 xref: EMBL:BAB14145.1 xref: EMBL:BAB71457.1 xref: EMBL:CAB53677.2 xref: EMBL:CAH70029.2 xref: EMBL:CAM18525.1 xref: UniProtKB:Q5TYW1 xref: UniProtKB:Q6PIP3 xref: UniProtKB:Q96M55 xref: UniProtKB:Q9H9S6 xref: UniProtKB:Q9UG02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020878 ! ZNF658_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056637 name: OR2G6_HUMAN def: "Olfactory receptor 2G6" [UniProtKB:Q5TZ20] xref: EMBL:CAH71962.1 xref: UniProtKB:Q5TZ20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019096 ! OR2G6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056638 name: MCAF2_HUMAN def: "Activating transcription factor 7-interacting protein 2" [UniProtKB:Q5U623] synonym: "MBD1-containing chromatin-associated factor 2" EXACT [UniProtKB:Q5U623] xref: EMBL:AAH33891.1 xref: EMBL:AAH69695.1 xref: EMBL:AAH69713.1 xref: EMBL:AAH69730.1 xref: EMBL:AAT66299.1 xref: EMBL:BAB14209.1 xref: EMBL:BAC04157.1 xref: EMBL:BAD97212.1 xref: EMBL:CAH56323.1 xref: UniProtKB:Q53EZ7 xref: UniProtKB:Q5U623 xref: UniProtKB:Q658U2 xref: UniProtKB:Q6IS97 xref: UniProtKB:Q8N9X8 xref: UniProtKB:Q9H9L6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018583 ! ATF7IP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056639 name: RAIN_HUMAN def: "Ras-interacting protein 1" [UniProtKB:Q5U651] synonym: "Rain" EXACT [UniProtKB:Q5U651] xref: EMBL:AAH28614.1 xref: EMBL:AAR24580.1 xref: UniProtKB:Q5U651 xref: UniProtKB:Q6U676 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019617 ! RASIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069722 ! RAIN_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0069723 ! RAIN_HUMAN-Phosphoserine331 [Term] id: CCO:B0056640 name: GP157_HUMAN def: "Probable G-protein coupled receptor 157" [UniProtKB:Q5UAW9] xref: EMBL:AAH18691.1 xref: EMBL:AAV35060.1 xref: EMBL:BAB13982.1 xref: EMBL:CAM12842.1 xref: UniProtKB:A2A334 xref: UniProtKB:Q5UAW9 xref: UniProtKB:Q8WWB8 xref: UniProtKB:Q9HA73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017980 ! GPR157_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056641 name: Q5UBV6_HUMAN def: "NIN/PDGFRB fusion protein" [UniProtKB:Q5UBV6] xref: EMBL:AAV37179.1 xref: UniProtKB:Q5UBV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021145 ! NIN/PDGFRB fusion_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0056642 name: ZN468_HUMAN def: "Zinc finger protein 468" [UniProtKB:Q5VIY5] xref: EMBL:AAS01603.1 xref: EMBL:AAS01604.1 xref: EMBL:CAH18233.1 xref: EMBL:CAI56747.1 xref: UniProtKB:Q5CZB8 xref: UniProtKB:Q5VIY4 xref: UniProtKB:Q5VIY5 xref: UniProtKB:Q68DI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020763 ! ZNF468_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056643 name: GKAP1_HUMAN def: "G kinase-anchoring protein 1" [UniProtKB:Q5VSY0] synonym: "cGMP-dependent protein kinase-anchoring protein of 42 kDa" EXACT [UniProtKB:Q5VSY0] xref: EMBL:AAG40320.1 xref: EMBL:AAH14476.1 xref: EMBL:BAB40454.1 xref: EMBL:BAB40455.1 xref: EMBL:BAB71712.1 xref: EMBL:CAH70734.1 xref: EMBL:CAH70735.1 xref: EMBL:CAI16010.1 xref: EMBL:CAI16011.1 xref: EMBL:EAW62665.1 xref: EMBL:EAW62666.1 xref: UniProtKB:Q5VSY0 xref: UniProtKB:Q96LI0 xref: UniProtKB:Q9BYI1 xref: UniProtKB:Q9BYI2 xref: UniProtKB:Q9H225 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017926 ! GKAP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066465 ! GKAP1_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0066466 ! GKAP1_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0066467 ! GKAP1_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0066468 ! GKAP1_HUMAN-Phosphoserine106 [Term] id: CCO:B0056644 name: Q5VT13_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q5VT13] xref: EMBL:BAG36448.1 xref: EMBL:BAG53628.1 xref: EMBL:CAC87490.1 xref: EMBL:CAH71243.1 xref: EMBL:EAW59395.1 xref: UniProtKB:Q5VT13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018034 ! GPR82_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056645 name: Q5VT14_HUMAN def: "G-protein-coupled receptor 34" [UniProtKB:Q5VT14] synonym: "G protein-coupled receptor 34" EXACT [UniProtKB:Q5VT14] synonym: "G protein-coupled receptor 34, isoform CRA_a" EXACT [UniProtKB:Q5VT14] xref: EMBL:AAZ99227.1 xref: EMBL:AAZ99230.1 xref: EMBL:CAH71242.1 xref: EMBL:EAW59396.1 xref: UniProtKB:Q5VT14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018017 ! GPR34_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056646 name: MRCKA_HUMAN def: "Serine/threonine-protein kinase MRCK alpha" [UniProtKB:Q5VT25] synonym: "CDC42-binding protein kinase alpha" EXACT [UniProtKB:Q5VT25] synonym: "DMPK-like alpha" EXACT [UniProtKB:Q5VT25] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q5VT25] synonym: "MRCK alpha" EXACT [UniProtKB:Q5VT25] synonym: "Myotonic dystrophy kinase-related CDC42-binding kinase alpha" EXACT [UniProtKB:Q5VT25] synonym: "Myotonic dystrophy protein kinase-like alpha" EXACT [UniProtKB:Q5VT25] xref: EMBL:AAB37126.1 xref: EMBL:BAA32296.2 xref: EMBL:BAD92205.1 xref: EMBL:CAD57745.1 xref: EMBL:CAD57746.1 xref: EMBL:CAH71183.1 xref: EMBL:CAH71184.1 xref: EMBL:CAH71185.1 xref: EMBL:CAH71336.1 xref: EMBL:CAH71337.1 xref: EMBL:CAH71338.1 xref: EMBL:CAI19108.1 xref: EMBL:CAI19109.1 xref: EMBL:CAI19110.1 xref: EMBL:CAI19113.1 xref: EMBL:CAI46252.1 xref: UniProtKB:O75039 xref: UniProtKB:Q59GZ1 xref: UniProtKB:Q5H9N9 xref: UniProtKB:Q5T797 xref: UniProtKB:Q5VT25 xref: UniProtKB:Q5VT26 xref: UniProtKB:Q5VT27 xref: UniProtKB:Q86XX2 xref: UniProtKB:Q86XX3 xref: UniProtKB:Q99646 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018651 ! CDC42BPA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0001172 ! leading edge relationship: participates_in CCO:I0017747 ! cdc42bpa -rhoq-1 physical interaction relationship: participates_in CCO:I0017757 ! cdc42bpa -cdc42-1 physical interaction relationship: participates_in CCO:I0018070 ! cdc42bpa-mlcb-1 phosphorylation relationship: participates_in CCO:I0018071 ! cdc42bpa-cdc42-2 direct interaction relationship: participates_in CCO:I0018072 ! cdc42bpa-cdc42-3 direct interaction relationship: participates_in CCO:I0018507 ! cdc42bpa-cdc42-1 direct interaction relationship: participates_in CCO:I0019391 ! cdc42bpa-cd42bpa-3 direct interaction relationship: participates_in CCO:I0019392 ! cdc42bpa-cd42bpa-4 direct interaction relationship: participates_in CCO:I0019393 ! cdc42bpa-cd42bpa-6 direct interaction relationship: participates_in CCO:I0019394 ! cdc42bpa-cd42bpa-9 direct interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0068269 ! MRCKA_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0068270 ! MRCKA_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0068271 ! MRCKA_HUMAN-Phosphothreonine240 relationship: transforms_into CCO:B0068272 ! MRCKA_HUMAN-Phosphoserine1545 relationship: transforms_into CCO:B0068273 ! MRCKA_HUMAN-Phosphoserine1719 relationship: transforms_into CCO:B0068274 ! MRCKA_HUMAN-Phosphoserine1721 [Term] id: CCO:B0056647 name: Q5VT36_HUMAN def: "Zinc finger protein 669" [UniProtKB:Q5VT36] xref: EMBL:CAH70018.1 xref: UniProtKB:Q5VT36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020885 ! ZNF669_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056648 name: Q5VT37_HUMAN def: "Zinc finger protein 669" [UniProtKB:Q5VT37] xref: EMBL:CAH70017.1 xref: UniProtKB:Q5VT37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020885 ! ZNF669_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056649 name: SYDE2_HUMAN def: "Rho GTPase-activating protein SYDE2" [UniProtKB:Q5VT97] synonym: "Protein syd-1 homolog 2" EXACT [UniProtKB:Q5VT97] synonym: "Synapse defective protein 1 homolog 2" EXACT [UniProtKB:Q5VT97] xref: EMBL:BAB14711.1 xref: EMBL:CAD38960.1 xref: EMBL:CAH72669.1 xref: EMBL:CAH72670.1 xref: UniProtKB:Q5VT96 xref: UniProtKB:Q5VT97 xref: UniProtKB:Q8NDB8 xref: UniProtKB:Q9H8A6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020085 ! SYDE2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001689 ! activation of Rho GTPase activity relationship: transforms_into CCO:B0071032 ! SYDE2_HUMAN-Phosphoserine544 [Term] id: CCO:B0056650 name: Q5VTU6_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:Q5VTU6] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q5VTU6] xref: EMBL:CAH70634.1 xref: EMBL:CAI12447.1 xref: EMBL:CAI17231.1 xref: UniProtKB:Q5VTU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021146 ! FLT3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0056651 name: Q5VTZ2_HUMAN def: "Activating transcription factor 3" [UniProtKB:Q5VTZ2] xref: EMBL:CAH72657.1 xref: UniProtKB:Q5VTZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004114 ! ATF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056652 name: Q5VTZ4_HUMAN def: "Activating transcription factor 3" [UniProtKB:Q5VTZ4] xref: EMBL:CAH72655.1 xref: UniProtKB:Q5VTZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004114 ! ATF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056653 name: Q5VUE2_HUMAN def: "LIM homeobox 9 (LIM homeobox 9, isoform CRA_f)" [UniProtKB:Q5VUE2] xref: EMBL:CAH71761.1 xref: EMBL:EAW91292.1 xref: UniProtKB:Q5VUE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018491 ! LHX9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056654 name: Q5VUE6_HUMAN def: "LIM homeobox 9" [UniProtKB:Q5VUE6] xref: EMBL:CAH71764.1 xref: UniProtKB:Q5VUE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018491 ! LHX9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056655 name: SMBT2_HUMAN def: "Scm-like with four MBT domains protein 2" [UniProtKB:Q5VUG0] xref: EMBL:BAB13443.1 xref: EMBL:CAH73318.1 xref: EMBL:CAI18944.1 xref: EMBL:CAI19142.1 xref: EMBL:CAI21746.1 xref: UniProtKB:Q5VUG0 xref: UniProtKB:Q9HCF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019947 ! SFMBT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056656 name: Q5VUM2_HUMAN xref: UniProtKB:Q5VUM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001407 ! receptor binding relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0056657 name: ARHGG_HUMAN def: "Rho guanine nucleotide exchange factor 16" [UniProtKB:Q5VV41] xref: EMBL:AAH02681.1 xref: EMBL:AAH51838.1 xref: EMBL:AAP35934.1 xref: EMBL:BAA13745.1 xref: EMBL:CAH70832.1 xref: EMBL:CAH70833.1 xref: UniProtKB:Q5VV41 xref: UniProtKB:Q86TF0 xref: UniProtKB:Q99434 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017022 ! ARHGEF16_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0063553 ! ARHGG_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0063554 ! ARHGG_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0063555 ! ARHGG_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0063556 ! ARHGG_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0063557 ! ARHGG_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0063558 ! ARHGG_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0063559 ! ARHGG_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0063560 ! ARHGG_HUMAN-Phosphoserine577 [Term] id: CCO:B0056658 name: IKBP1_HUMAN def: "Interleukin-1 receptor-associated kinase 1-binding protein 1" [UniProtKB:Q5VVH5] xref: EMBL:AAI12254.1 xref: EMBL:AAI12256.1 xref: EMBL:CAH70883.1 xref: EMBL:EAW48721.1 xref: UniProtKB:Q5VVH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018244 ! IRAK1BP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0067065 ! IKBP1_HUMAN-Phosphoserine56 relationship: transforms_into CCO:B0067066 ! IKBP1_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0067067 ! IKBP1_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0067068 ! IKBP1_HUMAN-Phosphothreonine237 relationship: transforms_into CCO:B0067069 ! IKBP1_HUMAN-Phosphoserine242 relationship: transforms_into CCO:B0067070 ! IKBP1_HUMAN-Phosphothreonine247 [Term] id: CCO:B0056659 name: MYSM1_HUMAN def: "Protein MYSM1" [UniProtKB:Q5VVJ2] synonym: "Myb-like, SWIRM and MPN domain-containing protein 1" EXACT [UniProtKB:Q5VVJ2] xref: EMBL:BAB67808.1 xref: EMBL:CAD97896.1 xref: EMBL:CAH70737.1 xref: EMBL:CAI21908.1 xref: UniProtKB:Q5VVJ2 xref: UniProtKB:Q7Z3G8 xref: UniProtKB:Q96PX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018703 ! MYSM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068420 ! MYSM1_HUMAN-Phosphoserine218 relationship: transforms_into CCO:B0068421 ! MYSM1_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0068422 ! MYSM1_HUMAN-Phosphoserine267 [Term] id: CCO:B0056660 name: Q5VVT2_HUMAN def: "H2.0-like homeobox" [UniProtKB:Q5VVT2] xref: EMBL:CAH72121.1 xref: UniProtKB:Q5VVT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018137 ! HLX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056661 name: GARL3_HUMAN def: "GTPase-activating Rap/Ran-GAP domain-like protein 3" [UniProtKB:Q5VVW2] xref: EMBL:AAH34983.1 xref: EMBL:BAC04605.1 xref: EMBL:CAB66508.1 xref: EMBL:CAD38860.1 xref: EMBL:CAH72927.1 xref: EMBL:CAI41459.1 xref: UniProtKB:Q5VVW2 xref: UniProtKB:Q8IYU1 xref: UniProtKB:Q8N951 xref: UniProtKB:Q8ND89 xref: UniProtKB:Q9BQH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017865 ! GARNL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0066381 ! GARL3_HUMAN-Phosphothreonine827 [Term] id: CCO:B0056662 name: Q5VWB9_HUMAN def: "Phosphatidylinositol 4-kinase, catalytic, beta polypeptide (Phosphatidylinositol 4-kinase, catalytic, beta polypeptide, isoform CRA_b)" [UniProtKB:Q5VWB9] xref: EMBL:CAH70326.1 xref: EMBL:EAW53450.1 xref: UniProtKB:Q5VWB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021038 ! PIK4CB_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0056663 name: TAF3_HUMAN def: "Transcription initiation factor TFIID subunit 3" [UniProtKB:Q5VWG9] synonym: "140 kDa TATA box-binding protein-associated factor" EXACT [UniProtKB:Q5VWG9] synonym: "TAF140" EXACT [UniProtKB:Q5VWG9] synonym: "TAFII140" EXACT [UniProtKB:Q5VWG9] synonym: "TBP-associated factor 3" EXACT [UniProtKB:Q5VWG9] synonym: "Transcription initiation factor TFIID 140 kDa subunit" EXACT [UniProtKB:Q5VWG9] xref: EMBL:AAH45106.1 xref: EMBL:AAH62352.1 xref: EMBL:AAH73884.1 xref: EMBL:CAB56032.1 xref: EMBL:CAC34475.1 xref: EMBL:CAH73142.1 xref: EMBL:CAH73451.1 xref: EMBL:CAI15661.1 xref: UniProtKB:Q5VWG9 xref: UniProtKB:Q6GMS5 xref: UniProtKB:Q6P6B5 xref: UniProtKB:Q86VY6 xref: UniProtKB:Q9BQS9 xref: UniProtKB:Q9UFI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020134 ! TAF3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071090 ! TAF3_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0071091 ! TAF3_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0071092 ! TAF3_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0071093 ! TAF3_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0071094 ! TAF3_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0071095 ! TAF3_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0071096 ! TAF3_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0071097 ! TAF3_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0071098 ! TAF3_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0071099 ! TAF3_HUMAN-Phosphoserine415 [Term] id: CCO:B0056664 name: Q5VWL4_HUMAN def: "Phospholipase C, epsilon 1 (Phospholipase C, epsilon 1, isoform CRA_a) (Putative uncharacterized protein PLCE1)" [UniProtKB:Q5VWL4] xref: EMBL:CAH70740.1 xref: EMBL:CAH73289.1 xref: EMBL:CAH73758.1 xref: EMBL:CAI16675.1 xref: EMBL:EAW50042.1 xref: UniProtKB:A6NGW0 xref: UniProtKB:Q5VWL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019433 ! PLCE1_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056665 name: Q5VX04_HUMAN def: "5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled)" [UniProtKB:Q5VX04] xref: EMBL:CAH69965.1 xref: UniProtKB:Q5VX04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016859 ! HTR7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001315 ! melanocortin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056666 name: Q5VXI4_HUMAN def: "Rho guanine nucleotide exchange factor (GEF) 10-like" [UniProtKB:Q5VXI4] xref: EMBL:CAH74137.1 xref: UniProtKB:Q5VXI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021147 ! ARHGEF10L_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0001997 ! positive regulation of sterol regulatory element binding protein target gene transcription relationship: participates_in CCO:P0003108 ! positive regulation of stress fiber formation [Term] id: CCO:B0056667 name: Q5VY89_HUMAN def: "Ras-like without CAAX 1" [UniProtKB:Q5VY89] xref: EMBL:CAH69944.1 xref: EMBL:CAH72622.1 xref: UniProtKB:Q5VY89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005495 ! RIT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056668 name: Q5VY92_HUMAN xref: UniProtKB:Q5VY92 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056669 name: Q5VY93_HUMAN def: "Rho/rac guanine nucleotide exchange factor (GEF) 2" [UniProtKB:Q5VY93] xref: EMBL:CAH72628.1 xref: UniProtKB:Q5VY93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021148 ! ARHGEF2_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056670 name: Q5VYX9_HUMAN xref: UniProtKB:Q5VYX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0056671 name: Q5VYY0_HUMAN xref: UniProtKB:Q5VYY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0056672 name: Q5VZ84_HUMAN def: "Zinc finger E-box binding homeobox 1" [UniProtKB:Q5VZ84] xref: EMBL:CAH74131.1 xref: EMBL:CAI12549.1 xref: EMBL:CAI15107.1 xref: EMBL:CAI17319.1 xref: UniProtKB:Q5VZ84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020576 ! ZEB1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056673 name: Q5VZB4_HUMAN def: "SLIT-ROBO Rho GTPase activating protein 2" [UniProtKB:Q5VZB4] xref: EMBL:CAH73675.1 xref: UniProtKB:Q5VZB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017816 ! SRGAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056674 name: DMRTA_HUMAN def: "Doublesex- and mab-3-related transcription factor A1" [UniProtKB:Q5VZB9] xref: EMBL:BAC04672.1 xref: EMBL:CAC16590.1 xref: EMBL:CAH73857.1 xref: UniProtKB:Q5VZB9 xref: UniProtKB:Q8N8Y9 xref: UniProtKB:Q9H4B9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017590 ! DMRTA1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056675 name: MAK10_HUMAN def: "Protein MAK10 homolog" [UniProtKB:Q5VZE5] synonym: "Embryonic growth-associated protein homolog" EXACT [UniProtKB:Q5VZE5] xref: EMBL:AAI17428.1 xref: EMBL:AAI17430.1 xref: EMBL:BAB15097.1 xref: EMBL:BAB15435.1 xref: EMBL:CAH73155.1 xref: EMBL:CAI12659.1 xref: EMBL:CAI16313.1 xref: EMBL:EAW62702.1 xref: UniProtKB:Q5VZE5 xref: UniProtKB:Q9H631 xref: UniProtKB:Q9H703 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018560 ! MAK10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002857 ! smooth muscle cell proliferation [Term] id: CCO:B0056676 name: RRAGB_HUMAN def: "Ras-related GTP-binding protein B" [UniProtKB:Q5VZM2] synonym: "Rag B" EXACT [UniProtKB:Q5VZM2] synonym: "RagB" EXACT [UniProtKB:Q5VZM2] xref: EMBL:AAH34726.1 xref: EMBL:CAA62132.1 xref: EMBL:CAD38586.1 xref: EMBL:CAH70826.1 xref: EMBL:CAH70827.1 xref: EMBL:CAI40804.1 xref: EMBL:CAI40805.1 xref: UniProtKB:Q15348 xref: UniProtKB:Q5VZM2 xref: UniProtKB:Q8N3T0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019793 ! RRAGB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016332 ! rragb-rragc-1 physical interaction relationship: participates_in CCO:I0016333 ! rragb-rragd-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056677 name: Q5VZN3_HUMAN def: "Zinc finger protein 483" [UniProtKB:Q5VZN3] xref: EMBL:CAH73467.1 xref: UniProtKB:Q5VZN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020769 ! ZNF483_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056678 name: Q5W0I9_HUMAN def: "RAB18, member RAS oncogene family" [UniProtKB:Q5W0I9] xref: EMBL:CAH70592.1 xref: UniProtKB:Q5W0I9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019575 ! RAB18_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056679 name: Q5W0J0_HUMAN def: "RAB18, member RAS oncogene family" [UniProtKB:Q5W0J0] xref: EMBL:CAH70591.1 xref: UniProtKB:Q5W0J0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019575 ! RAB18_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056680 name: Q5W1B2_HUMAN def: "cAMP responsive element modulator" [UniProtKB:Q5W1B2] xref: EMBL:CAH72500.1 xref: EMBL:CAI12147.1 xref: UniProtKB:Q5W1B2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017453 ! CREM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056681 name: Q5W9H1_HUMAN def: "KIAA0142 splice variant 1" [UniProtKB:Q5W9H1] xref: EMBL:BAD66826.1 xref: UniProtKB:Q5W9H1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021150 ! KIAA0142_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056682 name: Q5XG89_HUMAN def: "Zinc finger protein 717" [UniProtKB:Q5XG89] xref: EMBL:AAH84565.1 xref: UniProtKB:Q5XG89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020916 ! ZNF717_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056683 name: OTP_HUMAN def: "Homeobox protein orthopedia" [UniProtKB:Q5XKR4] xref: EMBL:AAH01800.1 xref: UniProtKB:Q5XKR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019246 ! OTP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000524 ! positive regulation of neuroblast proliferation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056684 name: Q5YLW1_HUMAN def: "Angiopoietin-A" [UniProtKB:Q5YLW1] xref: EMBL:AAL59669.1 xref: UniProtKB:Q5YLW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021151 ! AngA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056685 name: CD276_HUMAN def: "CD276 antigen precursor" [UniProtKB:Q5ZPR3] synonym: "4Ig-B7-H3" EXACT [UniProtKB:Q5ZPR3] synonym: "B7 homolog 3" EXACT [UniProtKB:Q5ZPR3] synonym: "B7-H3" EXACT [UniProtKB:Q5ZPR3] synonym: "CD276 antigen" EXACT [UniProtKB:Q5ZPR3] synonym: "Costimulatory molecule" EXACT [UniProtKB:Q5ZPR3] xref: EMBL:AAH62581.1 xref: EMBL:AAK15438.1 xref: EMBL:AAQ88709.1 xref: EMBL:BAC11243.1 xref: EMBL:BAC11344.1 xref: EMBL:BAC11692.1 xref: EMBL:CAE47548.1 xref: UniProtKB:Q5ZPR3 xref: UniProtKB:Q6P5Y4 xref: UniProtKB:Q6UXI2 xref: UniProtKB:Q8NBI8 xref: UniProtKB:Q8NC34 xref: UniProtKB:Q8NCB6 xref: UniProtKB:Q9BXR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017293 ! CD276_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: transforms_into CCO:B0064143 ! CD276_HUMAN-Phosphoserine525 [Term] id: CCO:B0056686 name: ZKSC2_HUMAN def: "Zinc finger protein with KRAB and SCAN domains 2" [UniProtKB:Q63HK3] synonym: "Zinc finger protein 694" EXACT [UniProtKB:Q63HK3] xref: EMBL:BAD18498.1 xref: EMBL:CAH56131.1 xref: UniProtKB:Q63HK3 xref: UniProtKB:Q6ZN77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020609 ! ZKSCAN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072040 ! ZKSC2_HUMAN-Phosphoserine591 relationship: transforms_into CCO:B0072041 ! ZKSC2_HUMAN-Phosphothreonine594 relationship: transforms_into CCO:B0072042 ! ZKSC2_HUMAN-Phosphoserine600 [Term] id: CCO:B0056687 name: TSH3_HUMAN def: "Teashirt homolog 3" [UniProtKB:Q63HK5] synonym: "Zinc finger protein 537" EXACT [UniProtKB:Q63HK5] xref: EMBL:BAA95998.1 xref: EMBL:CAB66739.1 xref: EMBL:CAH56184.1 xref: UniProtKB:Q63HK5 xref: UniProtKB:Q9H0G6 xref: UniProtKB:Q9P254 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020371 ! TSHZ3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071607 ! TSH3_HUMAN-Phosphoserine672 [Term] id: CCO:B0056688 name: PLCX3_HUMAN def: "Phosphatidylinositol-specific phospholipase C X domain-containing protein 3" [UniProtKB:Q63HM9] synonym: "PI-PLC X domain-containing protein 3" EXACT [UniProtKB:Q63HM9] xref: EMBL:CAH56150.1 xref: UniProtKB:Q63HM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019441 ! PLCXD3_human relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056689 name: Q63HN4_HUMAN def: "Putative uncharacterized protein DKFZp686J1732" [UniProtKB:Q63HN4] xref: EMBL:CAH56173.1 xref: UniProtKB:Q63HN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021152 ! DKFZp686J1732_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056690 name: TENC1_HUMAN def: "Tensin-like C1 domain-containing phosphatase" [UniProtKB:Q63HR2] synonym: "C1 domain-containing phosphatase and tensin homolog" EXACT [UniProtKB:Q63HR2] synonym: "C1-TEN" EXACT [UniProtKB:Q63HR2] synonym: "EC 3.1.3.-" EXACT [UniProtKB:Q63HR2] synonym: "Tensin-2" EXACT [UniProtKB:Q63HR2] xref: EMBL:AAH54099.1 xref: EMBL:AAI10855.1 xref: EMBL:AAI29829.1 xref: EMBL:AAI29830.1 xref: EMBL:AAI31504.1 xref: EMBL:AAL14641.1 xref: EMBL:AAM74225.1 xref: EMBL:AAN03866.1 xref: EMBL:BAA83027.2 xref: EMBL:CAB70815.1 xref: EMBL:CAH56176.1 xref: UniProtKB:A2VDF2 xref: UniProtKB:A2VDF3 xref: UniProtKB:A2VDI8 xref: UniProtKB:Q2NL80 xref: UniProtKB:Q63HR2 xref: UniProtKB:Q76MW6 xref: UniProtKB:Q7Z5T9 xref: UniProtKB:Q8NFF9 xref: UniProtKB:Q8NFG0 xref: UniProtKB:Q96P25 xref: UniProtKB:Q9NT29 xref: UniProtKB:Q9UPS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020230 ! TENC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0071325 ! TENC1_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0071326 ! TENC1_HUMAN-Phosphoserine466 relationship: transforms_into CCO:B0071327 ! TENC1_HUMAN-Phosphoserine481 relationship: transforms_into CCO:B0071328 ! TENC1_HUMAN-Phosphotyrosine483 relationship: transforms_into CCO:B0071329 ! TENC1_HUMAN-Phosphotyrosine770 relationship: transforms_into CCO:B0071330 ! TENC1_HUMAN-Phosphoserine832 relationship: transforms_into CCO:B0071331 ! TENC1_HUMAN-Phosphoserine835 relationship: transforms_into CCO:B0071332 ! TENC1_HUMAN-Phosphothreonine914 relationship: transforms_into CCO:B0071333 ! TENC1_HUMAN-Phosphoserine1003 [Term] id: CCO:B0056691 name: Q63ZY2_HUMAN def: "GPER protein" [UniProtKB:Q63ZY2] xref: EMBL:AAH82766.1 xref: UniProtKB:Q63ZY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018000 ! GPER_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056692 name: Q658N8_HUMAN def: "Putative uncharacterized protein DKFZp666D035" [UniProtKB:Q658N8] synonym: "Zinc finger protein 195" EXACT [UniProtKB:Q658N8] synonym: "Zinc finger protein 195, isoform CRA_b" EXACT [UniProtKB:Q658N8] xref: EMBL:AAI21029.1 xref: EMBL:CAH56261.1 xref: EMBL:EAX02549.1 xref: UniProtKB:Q658N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021153 ! DKFZp666D035_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056693 name: Q658W2_HUMAN def: "Putative uncharacterized protein DKFZp666O0110" [UniProtKB:Q658W2] xref: EMBL:CAH56296.1 xref: UniProtKB:Q658W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021154 ! DKFZp666O0110_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: participates_in CCO:P0000714 ! signal complex assembly [Term] id: CCO:B0056694 name: Q658W4_HUMAN def: "Putative uncharacterized protein DKFZp666M0710" [UniProtKB:Q658W4] xref: EMBL:CAH56283.1 xref: UniProtKB:Q658W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021155 ! DKFZp666M0710_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056695 name: TBC9B_HUMAN def: "TBC1 domain family member 9B" [UniProtKB:Q66K14] xref: EMBL:AAH08919.3 xref: EMBL:AAH80659.1 xref: EMBL:BAA31651.1 xref: EMBL:BAD97229.1 xref: EMBL:CAE46050.1 xref: UniProtKB:O75163 xref: UniProtKB:Q53EY0 xref: UniProtKB:Q66K14 xref: UniProtKB:Q6MZI2 xref: UniProtKB:Q96H49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020179 ! TBC1D9B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071220 ! TBC9B_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0071221 ! TBC9B_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0071222 ! TBC9B_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0071223 ! TBC9B_HUMAN-Phosphoserine435 relationship: transforms_into CCO:B0071224 ! TBC9B_HUMAN-Phosphoserine463 [Term] id: CCO:B0056696 name: Q66VZ3_HUMAN def: "Early B-cell factor 2" [UniProtKB:Q66VZ3] xref: EMBL:AAU10086.1 xref: UniProtKB:Q66VZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017427 ! EBF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056697 name: RPGP2_HUMAN def: "Rap1 GTPase-activating protein 2" [UniProtKB:Q684P5] synonym: "GTPase-activating Rap/Ran-GAP domain-like protein 4" EXACT [UniProtKB:Q684P5] synonym: "Rap1GAP2" EXACT [UniProtKB:Q684P5] xref: EMBL:BAA82991.1 xref: EMBL:BAC85912.1 xref: EMBL:CAF31652.1 xref: EMBL:CAF31653.1 xref: EMBL:CAH10514.1 xref: UniProtKB:Q684P4 xref: UniProtKB:Q684P5 xref: UniProtKB:Q6AI00 xref: UniProtKB:Q6ZVF0 xref: UniProtKB:Q9UPW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019791 ! GARNL4_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0070173 ! RPGP2_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0070174 ! RPGP2_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0070175 ! RPGP2_HUMAN-Phosphothreonine49 relationship: transforms_into CCO:B0070176 ! RPGP2_HUMAN-Phosphoserine544 relationship: transforms_into CCO:B0070177 ! RPGP2_HUMAN-Phosphoserine613 [Term] id: CCO:B0056698 name: CR3L3_HUMAN def: "cAMP-responsive element-binding protein 3-like protein 3" [UniProtKB:Q68CJ9] synonym: "Transcription factor CREB-H" EXACT [UniProtKB:Q68CJ9] xref: EMBL:AAI01505.1 xref: EMBL:AAI01509.1 xref: EMBL:BAB47242.1 xref: EMBL:BAD18804.1 xref: EMBL:BAD38649.1 xref: UniProtKB:Q68CJ9 xref: UniProtKB:Q6ZMC5 xref: UniProtKB:Q96TB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017448 ! CREB3L3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018084 ! atf6-hyst1481 physical interaction relationship: participates_in CCO:I0018085 ! atf6-hyst1481-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0064461 ! CR3L3_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0064462 ! CR3L3_HUMAN-Phosphoserine260 [Term] id: CCO:B0056699 name: Q68CU0_HUMAN def: "Putative uncharacterized protein DKFZp686A1965" [UniProtKB:Q68CU0] xref: EMBL:CAH18648.1 xref: UniProtKB:Q68CU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021156 ! DKFZp686A1965_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056700 name: Q68CY8_HUMAN def: "Putative uncharacterized protein DKFZp686D1580" [UniProtKB:Q68CY8] xref: EMBL:CAH18442.1 xref: UniProtKB:Q68CY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021157 ! DKFZp686D1580_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056701 name: Q68D02_HUMAN def: "Putative uncharacterized protein DKFZp686J099" [UniProtKB:Q68D02] xref: EMBL:CAH18428.1 xref: UniProtKB:Q68D02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021158 ! DKFZp686J099_human relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056702 name: K2018_HUMAN def: "Basic helix-loop-helix domain-containing protein KIAA2018" [UniProtKB:Q68DE3] xref: EMBL:BAB14518.1 xref: EMBL:BAC23114.1 xref: EMBL:CAD97821.1 xref: EMBL:CAH18277.1 xref: UniProtKB:Q68DE3 xref: UniProtKB:Q7Z3L9 xref: UniProtKB:Q8IVF3 xref: UniProtKB:Q9H8T4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018372 ! KIAA2018_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0067242 ! K2018_HUMAN-Phosphoserine1769 relationship: transforms_into CCO:B0067243 ! K2018_HUMAN-Phosphoserine1775 [Term] id: CCO:B0056703 name: Q68DF1_HUMAN def: "Putative uncharacterized protein DKFZp779B0247" [UniProtKB:Q68DF1] xref: EMBL:CAH18269.1 xref: UniProtKB:Q68DF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021160 ! DKFZp779B0247_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056704 name: Q68DL5_HUMAN def: "Putative uncharacterized protein DKFZp686M13211" [UniProtKB:Q68DL5] xref: EMBL:CAH18205.1 xref: UniProtKB:Q68DL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021161 ! DKFZp686M13211_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056705 name: Q68DR4_HUMAN def: "Putative uncharacterized protein DKFZp686H10254" [UniProtKB:Q68DR4] xref: EMBL:CAH18156.1 xref: UniProtKB:Q68DR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021162 ! DKFZp686H10254_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056706 name: Q68DZ5_HUMAN def: "Putative uncharacterized protein DKFZp686L0365" [UniProtKB:Q68DZ5] synonym: "cDNA FLJ58316, highly similar to Beta-arrestin-2" EXACT [UniProtKB:Q68DZ5] xref: EMBL:BAG59581.1 xref: EMBL:CAH18075.1 xref: UniProtKB:Q68DZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021163 ! DKFZp686L0365_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056707 name: Q68E09_HUMAN def: "Putative uncharacterized protein DKFZp686N1969" [UniProtKB:Q68E09] xref: EMBL:CAH18061.1 xref: UniProtKB:Q68E09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021164 ! DKFZp686N1969_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056708 name: Q68E11_HUMAN def: "Putative uncharacterized protein DKFZp686G16234" [UniProtKB:Q68E11] xref: EMBL:CAH18059.1 xref: UniProtKB:Q68E11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021165 ! DKFZp686G16234_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0056709 name: ZNF57_HUMAN def: "Zinc finger protein 57" [UniProtKB:Q68EA5] synonym: "Zinc finger protein 424" EXACT [UniProtKB:Q68EA5] xref: EMBL:AAH28974.1 xref: EMBL:CAH18455.2 xref: UniProtKB:Q68EA5 xref: UniProtKB:Q8N6R9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020978 ! ZNF57_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056710 name: LHX8_HUMAN def: "LIM/homeobox protein Lhx8" [UniProtKB:Q68G74] synonym: "LIM homeobox protein 8" EXACT [UniProtKB:Q68G74] xref: EMBL:AAH40321.1 xref: UniProtKB:Q68G74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018490 ! LHX8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056711 name: Q68HC0_HUMAN def: "Caspase 10 splice variant G" [UniProtKB:Q68HC0] xref: EMBL:AAU00989.1 xref: UniProtKB:Q68HC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017240 ! CASP10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056712 name: NAIF1_HUMAN def: "Nuclear apoptosis-inducing factor 1" [UniProtKB:Q69YI7] xref: EMBL:AAH21580.1 xref: EMBL:CAH10588.1 xref: EMBL:CAH73132.1 xref: UniProtKB:Q69YI7 xref: UniProtKB:Q8WU12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022426 ! NAIF1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0056713 name: PKHM4_HUMAN def: "Pleckstrin homology domain-containing family M member 4" [UniProtKB:Q69YJ1] xref: EMBL:CAH10578.1 xref: UniProtKB:Q69YJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069360 ! PKHM4_HUMAN-Phosphoserine473 relationship: transforms_into CCO:B0069361 ! PKHM4_HUMAN-Phosphoserine488 relationship: transforms_into CCO:B0069362 ! PKHM4_HUMAN-Phosphothreonine492 [Term] id: CCO:B0056714 name: Q6AHX5_HUMAN xref: UniProtKB:Q6AHX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056715 name: Z518A_HUMAN def: "Zinc finger protein 518A" [UniProtKB:Q6AHZ1] xref: EMBL:AAH30967.1 xref: EMBL:AAI09046.1 xref: EMBL:AAI09047.1 xref: EMBL:BAA20793.2 xref: EMBL:CAH10523.1 xref: UniProtKB:A0PJI5 xref: UniProtKB:O15044 xref: UniProtKB:Q32MP4 xref: UniProtKB:Q6AHZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020529 ! ZNF518A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071943 ! Z518A_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0071944 ! Z518A_HUMAN-Phosphoserine655 [Term] id: CCO:B0056716 name: Q6AI30_HUMAN def: "Putative uncharacterized protein DKFZp781L0674" [UniProtKB:Q6AI30] xref: EMBL:CAH10484.1 xref: UniProtKB:Q6AI30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021166 ! DKFZp781L0674_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056717 name: Q6AW80_HUMAN def: "Putative uncharacterized protein DKFZp779O0162" [UniProtKB:Q6AW80] xref: EMBL:CAH10551.1 xref: UniProtKB:Q6AW80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021167 ! DKFZp779O0162_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056718 name: Z324B_HUMAN def: "Zinc finger protein 324B" [UniProtKB:Q6AW86] xref: EMBL:BAC87113.1 xref: EMBL:BAD18597.1 xref: EMBL:CAH10556.1 xref: UniProtKB:Q6AW86 xref: UniProtKB:Q6ZMX8 xref: UniProtKB:Q6ZS42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020522 ! ZNF324B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056719 name: ZN660_HUMAN def: "Zinc finger protein 660" [UniProtKB:Q6AZW8] xref: EMBL:AAH75094.1 xref: EMBL:AAH75095.1 xref: EMBL:BAC04303.1 xref: EMBL:CAD98047.1 xref: UniProtKB:Q6AZW8 xref: UniProtKB:Q7Z331 xref: UniProtKB:Q8N9M8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020879 ! ZNF660_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056720 name: SP5_HUMAN def: "Transcription factor Sp5" [UniProtKB:Q6BEB4] xref: EMBL:BAD34944.1 xref: UniProtKB:Q6BEB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020004 ! SP5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056721 name: Q6DCA4_HUMAN def: "LOC554248 protein" [UniProtKB:Q6DCA4] xref: EMBL:AAH78169.1 xref: UniProtKB:Q6DCA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021168 ! LOC554248_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0056722 name: Q6DCB4_HUMAN def: "TBC1D3 protein" [UniProtKB:Q6DCB4] xref: EMBL:AAH78140.1 xref: UniProtKB:Q6DCB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020172 ! TBC1D3_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056723 name: ZN787_HUMAN def: "Zinc finger protein 787" [UniProtKB:Q6DD87] synonym: "TTF-I-interacting peptide 20" EXACT [UniProtKB:Q6DD87] xref: EMBL:AAB58413.1 xref: EMBL:AAH77728.1 xref: UniProtKB:O00455 xref: UniProtKB:Q6DD87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020940 ! ZNF787_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072241 ! ZN787_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0072242 ! ZN787_HUMAN-Phosphothreonine117 relationship: transforms_into CCO:B0072243 ! ZN787_HUMAN-Phosphotyrosine122 relationship: transforms_into CCO:B0072244 ! ZN787_HUMAN-Phosphotyrosine150 relationship: transforms_into CCO:B0072245 ! ZN787_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0072246 ! ZN787_HUMAN-Phosphoserine173 [Term] id: CCO:B0056724 name: TBC3G_HUMAN def: "TBC1 domain family member 3G" [UniProtKB:Q6DHY5] xref: EMBL:AAH75809.1 xref: UniProtKB:Q6DHY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020177 ! TBC1D3G_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056725 name: NXN_HUMAN def: "Nucleoredoxin" [UniProtKB:Q6DKJ4] synonym: "EC 1.8.1.8" EXACT [UniProtKB:Q6DKJ4] xref: EMBL:AAH63828.1 xref: EMBL:AAH73845.1 xref: EMBL:AAI04635.1 xref: EMBL:BAB14171.1 xref: EMBL:BAB55122.1 xref: UniProtKB:Q3SWW6 xref: UniProtKB:Q6DKJ4 xref: UniProtKB:Q6P3U6 xref: UniProtKB:Q9H9Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018893 ! NXN_human relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006446 ! protein-disulfide reductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056726 name: MCTP2_HUMAN def: "Multiple C2 and transmembrane domain-containing protein 2" [UniProtKB:Q6DN12] xref: EMBL:AAH25708.1 xref: EMBL:AAH41387.1 xref: EMBL:AAI11025.1 xref: EMBL:AAI31528.1 xref: EMBL:AAT73060.1 xref: EMBL:BAA91998.1 xref: EMBL:BAA92048.1 xref: UniProtKB:A2RRC2 xref: UniProtKB:Q49AB0 xref: UniProtKB:Q6DN12 xref: UniProtKB:Q8TAX2 xref: UniProtKB:Q9NUS2 xref: UniProtKB:Q9NUW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018594 ! MCTP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: transforms_into CCO:B0068069 ! MCTP2_HUMAN-Phosphothreonine144 relationship: transforms_into CCO:B0068070 ! MCTP2_HUMAN-Phosphoserine145 [Term] id: CCO:B0056727 name: MCTP1_HUMAN def: "Multiple C2 and transmembrane domain-containing protein 1" [UniProtKB:Q6DN14] xref: EMBL:AAH30005.1 xref: EMBL:AAT73058.1 xref: EMBL:AAT73059.1 xref: EMBL:BAB15311.1 xref: EMBL:BAB71547.1 xref: EMBL:BAC03637.1 xref: UniProtKB:Q6DN13 xref: UniProtKB:Q6DN14 xref: UniProtKB:Q8N2W1 xref: UniProtKB:Q8NBA2 xref: UniProtKB:Q96LX0 xref: UniProtKB:Q9H6E8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018593 ! MCTP1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0056728 name: IQEC1_HUMAN def: "IQ motif and SEC7 domain-containing protein 1" [UniProtKB:Q6DN90] synonym: "ADP-ribosylation factors guanine nucleotide-exchange protein 100" EXACT [UniProtKB:Q6DN90] synonym: "ADP-ribosylation factors guanine nucleotide-exchange protein 2" EXACT [UniProtKB:Q6DN90] synonym: "Brefeldin-resistant Arf-GEF 2 protein" EXACT [UniProtKB:Q6DN90] xref: EMBL:AAH10267.1 xref: EMBL:AAT72063.1 xref: EMBL:BAA34483.2 xref: UniProtKB:O94863 xref: UniProtKB:Q6DN90 xref: UniProtKB:Q96D85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018305 ! IQSEC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0067136 ! IQEC1_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0067137 ! IQEC1_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0067138 ! IQEC1_HUMAN-Phosphothreonine362 relationship: transforms_into CCO:B0067139 ! IQEC1_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0067140 ! IQEC1_HUMAN-Phosphoserine515 [Term] id: CCO:B0056729 name: MRCKG_HUMAN def: "Serine/threonine-protein kinase MRCK gamma" [UniProtKB:Q6DT37] synonym: "CDC42-binding protein kinase gamma" EXACT [UniProtKB:Q6DT37] synonym: "DMPK-like gamma" EXACT [UniProtKB:Q6DT37] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q6DT37] synonym: "MRCK gamma" EXACT [UniProtKB:Q6DT37] synonym: "Myotonic dystrophy kinase-related CDC42-binding kinase gamma" EXACT [UniProtKB:Q6DT37] synonym: "Myotonic dystrophy protein kinase-like alpha" EXACT [UniProtKB:Q6DT37] xref: EMBL:AAT67172.1 xref: EMBL:CAA73006.1 xref: UniProtKB:O00565 xref: UniProtKB:Q6DT37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018653 ! CDC42BPG_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001172 ! leading edge relationship: participates_in CCO:I0017748 ! cdc42bpg -rhoq-1 physical interaction relationship: participates_in CCO:I0017756 ! cdc42bpg -cdc42-1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0068283 ! MRCKG_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0068284 ! MRCKG_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0068285 ! MRCKG_HUMAN-Phosphothreonine234 [Term] id: CCO:B0056730 name: GP139_HUMAN def: "Probable G-protein coupled receptor 139" [UniProtKB:Q6DWJ6] synonym: "G(q)-coupled orphan receptor GPRg1" EXACT [UniProtKB:Q6DWJ6] synonym: "G-protein-coupled receptor PGR3" EXACT [UniProtKB:Q6DWJ6] xref: EMBL:AAO85057.1 xref: EMBL:AAT65818.1 xref: EMBL:BAB89307.1 xref: EMBL:BAD97440.1 xref: UniProtKB:Q6DWJ6 xref: UniProtKB:Q86SP2 xref: UniProtKB:Q8TDU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017967 ! GPR139_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0056731 name: ZN470_HUMAN def: "Zinc finger protein 470" [UniProtKB:Q6ECI4] synonym: "Chondrogenesis zinc finger protein 1" EXACT [UniProtKB:Q6ECI4] synonym: "CZF-1" EXACT [UniProtKB:Q6ECI4] xref: EMBL:AAD23607.1 xref: EMBL:AAS64219.1 xref: EMBL:BAC85218.1 xref: UniProtKB:Q6ECI4 xref: UniProtKB:Q6ZPA1 xref: UniProtKB:Q9Y2N9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020765 ! ZNF470_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072134 ! ZN470_HUMAN-Phosphothreonine160 relationship: transforms_into CCO:B0072135 ! ZN470_HUMAN-Phosphothreonine162 relationship: transforms_into CCO:B0072136 ! ZN470_HUMAN-Phosphothreonine166 [Term] id: CCO:B0056732 name: GTD2B_HUMAN def: "General transcription factor II-I repeat domain-containing protein 2B" [UniProtKB:Q6EKJ0] synonym: "GTF2I repeat domain-containing protein 2B" EXACT [UniProtKB:Q6EKJ0] synonym: "Transcription factor GTF2IRD2-beta" EXACT [UniProtKB:Q6EKJ0] xref: EMBL:AAR36863.1 xref: EMBL:AAR36864.1 xref: EMBL:BAB15060.1 xref: EMBL:BAC04576.1 xref: UniProtKB:Q69GU6 xref: UniProtKB:Q6EKJ0 xref: UniProtKB:Q8N979 xref: UniProtKB:Q9H739 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018089 ! GTF2IRD2B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056733 name: SFRP4_HUMAN def: "Secreted frizzled-related protein 4 precursor" [UniProtKB:Q6FHJ7] synonym: "Frizzled protein, human endometrium" EXACT [UniProtKB:Q6FHJ7] synonym: "FrpHE" EXACT [UniProtKB:Q6FHJ7] synonym: "sFRP-4" EXACT [UniProtKB:Q6FHJ7] xref: EMBL:AAC04617.1 xref: EMBL:AAH32828.1 xref: EMBL:AAH58911.1 xref: EMBL:AAV38485.1 xref: EMBL:CAG46532.1 xref: EMBL:CAG46555.1 xref: UniProtKB:O14877 xref: UniProtKB:Q4G124 xref: UniProtKB:Q6FHJ7 xref: UniProtKB:Q6FHM0 xref: UniProtKB:Q6PD64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019876 ! SFRP4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056734 name: Q6GMT1_HUMAN def: "Opsin 3" [UniProtKB:Q6GMT1] synonym: "Opsin 3 (Encephalopsin, panopsin), isoform CRA_b" EXACT [UniProtKB:Q6GMT1] xref: EMBL:AAH73872.1 xref: EMBL:EAW70098.1 xref: UniProtKB:Q6GMT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019049 ! OPN3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056735 name: OTU7B_HUMAN def: "OTU domain-containing protein 7B" [UniProtKB:Q6GQQ9] synonym: "Cellular zinc finger anti-NF-kappa-B protein" EXACT [UniProtKB:Q6GQQ9] synonym: "EC 3.-.-.-" EXACT [UniProtKB:Q6GQQ9] synonym: "Zinc finger A20 domain-containing protein 1" EXACT [UniProtKB:Q6GQQ9] synonym: "Zinc finger protein Cezanne" EXACT [UniProtKB:Q6GQQ9] xref: EMBL:AAH20622.1 xref: EMBL:AAH72681.1 xref: EMBL:CAB59268.1 xref: EMBL:CAB97494.1 xref: UniProtKB:Q6GQQ9 xref: UniProtKB:Q8WWA7 xref: UniProtKB:Q9NQ53 xref: UniProtKB:Q9UFF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019247 ! OTUD7B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016265 ! traf6-cezanne physical interaction relationship: participates_in CCO:P0002163 ! negative regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0069005 ! OTU7B_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0069006 ! OTU7B_HUMAN-Phosphoserine449 [Term] id: CCO:B0056736 name: GRIPE_HUMAN def: "GTPase-activating Rap/Ran-GAP domain-like 1" [UniProtKB:Q6GYQ0] synonym: "GAP-related-interacting partner to E12" EXACT [UniProtKB:Q6GYQ0] synonym: "GRIPE" EXACT [UniProtKB:Q6GYQ0] synonym: "Tuberin-like protein 1" EXACT [UniProtKB:Q6GYQ0] xref: EMBL:AAH42013.1 xref: EMBL:AAH42045.1 xref: EMBL:AAT49271.1 xref: EMBL:AAT49272.1 xref: EMBL:BAA74907.1 xref: EMBL:BAC86772.1 xref: EMBL:CAD39026.1 xref: UniProtKB:A6NMA4 xref: UniProtKB:O94960 xref: UniProtKB:Q6GYP9 xref: UniProtKB:Q6GYQ0 xref: UniProtKB:Q6ZT23 xref: UniProtKB:Q86YF3 xref: UniProtKB:Q86YF5 xref: UniProtKB:Q8ND69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018070 ! GARNL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0066612 ! GRIPE_HUMAN-Phosphothreonine754 relationship: transforms_into CCO:B0066613 ! GRIPE_HUMAN-Phosphoserine773 relationship: transforms_into CCO:B0066614 ! GRIPE_HUMAN-Phosphothreonine778 relationship: transforms_into CCO:B0066615 ! GRIPE_HUMAN-Phosphoserine797 relationship: transforms_into CCO:B0066616 ! GRIPE_HUMAN-Phosphoserine860 relationship: transforms_into CCO:B0066617 ! GRIPE_HUMAN-Phosphoserine861 relationship: transforms_into CCO:B0066618 ! GRIPE_HUMAN-Phosphoserine864 [Term] id: CCO:B0056737 name: Q6GZ68_HUMAN def: "Constitutive androstane receptor SV22" [UniProtKB:Q6GZ68] xref: EMBL:AAT47180.1 xref: UniProtKB:Q6GZ68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056738 name: Q6GZ69_HUMAN def: "Constitutive androstane receptor SV21" [UniProtKB:Q6GZ69] xref: EMBL:AAT47179.1 xref: UniProtKB:Q6GZ69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056739 name: Q6GZ72_HUMAN def: "Constitutive androstane receptor SV17" [UniProtKB:Q6GZ72] synonym: "Constitutive androstane receptor SV18" EXACT [UniProtKB:Q6GZ72] xref: EMBL:AAT47175.1 xref: EMBL:AAT47176.1 xref: UniProtKB:Q6GZ72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056740 name: Q6GZ75_HUMAN def: "Constitutive androstane receptor SV15" [UniProtKB:Q6GZ75] xref: EMBL:AAT47173.1 xref: UniProtKB:Q6GZ75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056741 name: Q6GZ76_HUMAN def: "Constitutive androstane receptor SV14" [UniProtKB:Q6GZ76] xref: EMBL:AAT47172.1 xref: UniProtKB:Q6GZ76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056742 name: Q6GZ77_HUMAN def: "Constitutive androstane receptor SV13" [UniProtKB:Q6GZ77] xref: EMBL:AAT47171.1 xref: UniProtKB:Q6GZ77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056743 name: Q6GZ78_HUMAN def: "Constitutive androstane receptor SV12" [UniProtKB:Q6GZ78] xref: EMBL:AAT47170.1 xref: UniProtKB:Q6GZ78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056744 name: Q6GZ79_HUMAN def: "Constitutive androstane receptor SV11" [UniProtKB:Q6GZ79] xref: EMBL:AAT47169.1 xref: UniProtKB:Q6GZ79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056745 name: Q6GZ81_HUMAN def: "Constitutive androstane receptor SV10" [UniProtKB:Q6GZ81] synonym: "Constitutive androstane receptor SV4" EXACT [UniProtKB:Q6GZ81] synonym: "Constitutive androstane receptor SV9" EXACT [UniProtKB:Q6GZ81] xref: EMBL:AAT47162.1 xref: EMBL:AAT47167.1 xref: EMBL:AAT47168.1 xref: UniProtKB:Q6GZ81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056746 name: Q6GZ82_HUMAN def: "Constitutive androstane receptor SV8" [UniProtKB:Q6GZ82] xref: EMBL:AAT47166.1 xref: UniProtKB:Q6GZ82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056747 name: Q6GZ83_HUMAN def: "Constitutive androstane receptor SV7" [UniProtKB:Q6GZ83] xref: EMBL:AAT47165.1 xref: UniProtKB:Q6GZ83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056748 name: Q6GZ84_HUMAN def: "Constitutive androstane receptor SV6" [UniProtKB:Q6GZ84] xref: EMBL:AAT47164.1 xref: UniProtKB:Q6GZ84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056749 name: Q6GZ85_HUMAN def: "Constitutive androstane receptor SV5" [UniProtKB:Q6GZ85] synonym: "Nuclear receptor subfamily 1, group I, member 3" EXACT [UniProtKB:Q6GZ85] xref: EMBL:AAI21122.1 xref: EMBL:AAT47163.1 xref: UniProtKB:Q6GZ85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056750 name: Q6GZ87_HUMAN def: "Constitutive androstane receptor SV3" [UniProtKB:Q6GZ87] xref: EMBL:AAT47161.1 xref: UniProtKB:Q6GZ87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056751 name: Q6GZ89_HUMAN def: "Constitutive androstane receptor SV1" [UniProtKB:Q6GZ89] xref: EMBL:AAT47159.1 xref: UniProtKB:Q6GZ89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056752 name: Q6I939_HUMAN xref: UniProtKB:Q6I939 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056753 name: Q6I940_HUMAN xref: UniProtKB:Q6I940 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056754 name: Q6I941_HUMAN xref: UniProtKB:Q6I941 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056755 name: Q6I9S1_HUMAN def: "NR1D2 protein" [UniProtKB:Q6I9S1] xref: EMBL:CAG33715.1 xref: UniProtKB:Q6I9S1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018850 ! NR1D2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056756 name: SIGIR_HUMAN def: "Single Ig IL-1-related receptor" [UniProtKB:Q6IA17] synonym: "Single Ig IL-1R-related molecule" EXACT [UniProtKB:Q6IA17] synonym: "Single immunoglobulin domain-containing IL1R-related protein" EXACT [UniProtKB:Q6IA17] synonym: "TIR8" EXACT [UniProtKB:Q6IA17] synonym: "Toll/interleukin-1 receptor 8" EXACT [UniProtKB:Q6IA17] xref: EMBL:AAH03591.1 xref: EMBL:AAH25953.1 xref: EMBL:AAI06008.1 xref: EMBL:AAQ88708.1 xref: EMBL:BAB15066.1 xref: EMBL:CAG33619.1 xref: UniProtKB:Q3KQY2 xref: UniProtKB:Q6IA17 xref: UniProtKB:Q6UXI3 xref: UniProtKB:Q9H733 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019905 ! SIGIRR_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0020303 ! eno2-sigirr physical interaction relationship: participates_in CCO:I0020656 ! rpn1-sigirr physical interaction relationship: participates_in CCO:P0000512 ! negative regulation of cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001486 ! negative regulation of lipopolysaccharide-mediated signaling pathway relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: participates_in CCO:P0002271 ! negative regulation of chemokine biosynthetic process relationship: transforms_into CCO:B0070533 ! SIGIR_HUMAN-Phosphoserine380 [Term] id: CCO:B0056757 name: Q6IAN2_HUMAN def: "FAIM protein" [UniProtKB:Q6IAN2] xref: EMBL:CAG33403.1 xref: UniProtKB:Q6IAN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017758 ! FAIM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0056758 name: Q6IB99_HUMAN def: "C12orf2 protein" [UniProtKB:Q6IB99] xref: EMBL:CAG33186.1 xref: UniProtKB:Q6IB99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021169 ! C12orf2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056759 name: JADE1_HUMAN def: "Protein Jade-1" [UniProtKB:Q6IE81] synonym: "PHD finger protein 17" EXACT [UniProtKB:Q6IE81] xref: EMBL:AAH32376.1 xref: EMBL:AAM95612.1 xref: EMBL:AAY40997.1 xref: EMBL:BAB15371.1 xref: EMBL:BAB47436.1 xref: EMBL:BAB55239.1 xref: EMBL:BAC11335.1 xref: EMBL:BAC86931.1 xref: EMBL:CAE30500.1 xref: UniProtKB:Q4W5D5 xref: UniProtKB:Q6IE81 xref: UniProtKB:Q6ZSL7 xref: UniProtKB:Q8NC41 xref: UniProtKB:Q96JL8 xref: UniProtKB:Q96SQ1 xref: UniProtKB:Q9H692 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018355 ! PHF17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: transforms_into CCO:B0067188 ! JADE1_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0067189 ! JADE1_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0067190 ! JADE1_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0067191 ! JADE1_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0067192 ! JADE1_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0067193 ! JADE1_HUMAN-Phosphothreonine92 [Term] id: CCO:B0056760 name: OR5MA_HUMAN def: "Olfactory receptor 5M10" [UniProtKB:Q6IEU7] synonym: "Olfactory receptor OR11-207" EXACT [UniProtKB:Q6IEU7] xref: EMBL:DAA04913.1 xref: UniProtKB:Q6IEU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019191 ! OR5M10_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056761 name: Q6IEV0_HUMAN def: "Olfactory receptor OR11-215" [UniProtKB:Q6IEV0] xref: EMBL:DAA04910.1 xref: UniProtKB:Q6IEV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056762 name: Q6IEV1_HUMAN def: "Olfactory receptor OR11-210" [UniProtKB:Q6IEV1] xref: EMBL:DAA04909.1 xref: UniProtKB:Q6IEV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056763 name: Q6IEV3_HUMAN def: "Olfactory receptor OR11-279 (Olfactory receptor, family 10, subfamily S, member 1)" [UniProtKB:Q6IEV3] xref: EMBL:AAI37039.1 xref: EMBL:DAA04907.1 xref: UniProtKB:Q6IEV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021170 ! OR10S1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056764 name: OR4CB_HUMAN def: "Olfactory receptor 4C11" [UniProtKB:Q6IEV9] synonym: "Olfactory receptor OR11-136" EXACT [UniProtKB:Q6IEV9] xref: EMBL:BAC05994.1 xref: EMBL:DAA04901.1 xref: UniProtKB:Q6IEV9 xref: UniProtKB:Q8NGL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019138 ! OR4C11_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056765 name: Q6IEW7_HUMAN xref: UniProtKB:Q6IEW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056766 name: Q6IEX0_HUMAN xref: UniProtKB:Q6IEX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056767 name: Q6IEX5_HUMAN def: "Olfactory receptor OR14-4" [UniProtKB:Q6IEX5] xref: EMBL:DAA04885.1 xref: UniProtKB:Q6IEX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056768 name: OR4F3_HUMAN def: "Olfactory receptor 4F3/4F16/4F29" [UniProtKB:Q6IEY1] synonym: "Olfactory receptor OR1-1" EXACT [UniProtKB:Q6IEY1] xref: EMBL:CAI22294.1 xref: EMBL:DAA04879.1 xref: UniProtKB:Q6IEY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019152 ! OR4F3_human relationship: encoded_by CCO:G0019153 ! OR4F16_human relationship: encoded_by CCO:G0019154 ! OR4F29_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056769 name: Q6IEZ1_HUMAN def: "Olfactory receptor OR1-30" [UniProtKB:Q6IEZ1] xref: EMBL:DAA04869.1 xref: UniProtKB:Q6IEZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056770 name: Q6IEZ4_HUMAN def: "Olfactory receptor OR14-20" [UniProtKB:Q6IEZ4] xref: EMBL:DAA04866.1 xref: UniProtKB:Q6IEZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056771 name: OR2T5_HUMAN def: "Olfactory receptor 2T5" [UniProtKB:Q6IEZ7] synonym: "Olfactory receptor OR1-62" EXACT [UniProtKB:Q6IEZ7] xref: EMBL:DAA04863.1 xref: UniProtKB:Q6IEZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019119 ! OR2T5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056772 name: OR2T2_HUMAN def: "Olfactory receptor 2T2" [UniProtKB:Q6IF00] synonym: "Olfactory receptor OR1-43" EXACT [UniProtKB:Q6IF00] xref: EMBL:DAA04860.1 xref: UniProtKB:Q6IF00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019116 ! OR2T2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056773 name: Q6IF09_HUMAN xref: UniProtKB:Q6IF09 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056774 name: Q6IF12_HUMAN def: "Olfactory receptor OR14-29" [UniProtKB:Q6IF12] xref: EMBL:DAA04848.1 xref: UniProtKB:Q6IF12 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056775 name: Q6IF17_HUMAN def: "Olfactory receptor OR9-23" [UniProtKB:Q6IF17] xref: EMBL:DAA04843.1 xref: UniProtKB:Q6IF17 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056776 name: Q6IF36_HUMAN def: "Olfactory receptor OR11-292 (Olfactory receptor, family 8, subfamily G, member 2)" [UniProtKB:Q6IF36] xref: EMBL:AAI36639.1 xref: EMBL:DAA04824.1 xref: UniProtKB:Q6IF36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014891 ! OR8G2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056777 name: Q6IF40_HUMAN def: "Olfactory receptor OR7-15 (HCG2044305)" [UniProtKB:Q6IF40] xref: EMBL:DAA04820.1 xref: EMBL:EAW55634.1 xref: UniProtKB:Q6IF40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021171 ! hCG_2044305_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056778 name: OR2A2_HUMAN def: "Olfactory receptor 2A2" [UniProtKB:Q6IF42] synonym: "Olfactory receptor OR7-11" EXACT [UniProtKB:Q6IF42] xref: EMBL:BAC05918.1 xref: EMBL:DAA04818.1 xref: UniProtKB:Q6IF42 xref: UniProtKB:Q8NGT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019080 ! OR2A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056779 name: Q6IF52_HUMAN def: "Olfactory receptor OR9-8 (Olfactory receptor, family 13, subfamily C, member 3)" [UniProtKB:Q6IF52] xref: EMBL:AAI36950.1 xref: EMBL:AAI36953.1 xref: EMBL:DAA04808.1 xref: UniProtKB:Q6IF52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021172 ! OR13C3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056780 name: O52W1_HUMAN def: "Olfactory receptor 52W1" [UniProtKB:Q6IF63] synonym: "Olfactory receptor OR11-71" EXACT [UniProtKB:Q6IF63] xref: EMBL:AAI37226.1 xref: EMBL:BAC05759.1 xref: EMBL:DAA04797.1 xref: UniProtKB:Q6IF63 xref: UniProtKB:Q8NH78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019023 ! OR52W1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056781 name: Q6IF70_HUMAN def: "Olfactory receptor OR7-3" [UniProtKB:Q6IF70] xref: EMBL:DAA04790.1 xref: UniProtKB:Q6IF70 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056782 name: Q6IF79_HUMAN def: "Olfactory receptor OR11-45" [UniProtKB:Q6IF79] xref: EMBL:DAA04781.1 xref: UniProtKB:Q6IF79 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056783 name: O4A47_HUMAN def: "Olfactory receptor 4A47" [UniProtKB:Q6IF82] synonym: "Olfactory receptor OR11-113" EXACT [UniProtKB:Q6IF82] xref: EMBL:DAA04778.1 xref: UniProtKB:Q6IF82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018974 ! OR4A47_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056784 name: O10K2_HUMAN def: "Olfactory receptor 10K2" [UniProtKB:Q6IF99] synonym: "Olfactory receptor OR1-4" EXACT [UniProtKB:Q6IF99] xref: EMBL:CAI10868.1 xref: EMBL:DAA04761.1 xref: UniProtKB:Q6IF99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018925 ! OR10K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056785 name: Q6IFB0_HUMAN def: "Olfactory receptor OR17-17" [UniProtKB:Q6IFB0] xref: EMBL:DAA04750.1 xref: UniProtKB:Q6IFB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056786 name: Q6IFD1_HUMAN def: "Olfactory receptor OR11-140 (HCG2044349)" [UniProtKB:Q6IFD1] xref: EMBL:DAA04729.1 xref: EMBL:EAW73680.1 xref: UniProtKB:Q6IFD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021173 ! hCG_2044349_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056787 name: Q6IFD3_HUMAN def: "Olfactory receptor OR11-152 (Olfactory receptor, family 5, subfamily D, member 18)" [UniProtKB:Q6IFD3] xref: EMBL:AAI36926.1 xref: EMBL:AAI36928.1 xref: EMBL:DAA04727.1 xref: EMBL:EAW73685.1 xref: UniProtKB:Q6IFD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019184 ! OR5D18_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056788 name: Q6IFD6_HUMAN def: "Olfactory receptor OR12-2" [UniProtKB:Q6IFD6] xref: EMBL:DAA04724.1 xref: UniProtKB:Q6IFD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056789 name: O52E8_HUMAN def: "Olfactory receptor 52E8" [UniProtKB:Q6IFG1] synonym: "Olfactory receptor OR11-54" EXACT [UniProtKB:Q6IFG1] xref: EMBL:DAA04699.1 xref: UniProtKB:Q6IFG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019012 ! OR52E8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0068950 ! O52E8_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0068951 ! O52E8_HUMAN-Phosphoserine144 [Term] id: CCO:B0056790 name: Q6IFG3_HUMAN def: "Olfactory receptor OR11-232 (Olfactory receptor, family 1, subfamily S, member 1)" [UniProtKB:Q6IFG3] xref: EMBL:DAA04697.1 xref: EMBL:EAW73800.1 xref: UniProtKB:Q6IFG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021174 ! OR1S1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056791 name: Q6IFG5_HUMAN def: "Olfactory receptor OR11-231" [UniProtKB:Q6IFG5] xref: EMBL:DAA04695.1 xref: UniProtKB:Q6IFG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056792 name: Q6IFG6_HUMAN def: "Olfactory receptor OR11-85 (Olfactory receptor, family 10, subfamily A, member 5)" [UniProtKB:Q6IFG6] xref: EMBL:DAA04694.1 xref: EMBL:EAW68675.1 xref: UniProtKB:Q6IFG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018900 ! OR10A5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056793 name: Q6IFG8_HUMAN def: "Olfactory receptor OR11-89" [UniProtKB:Q6IFG8] xref: EMBL:DAA04692.1 xref: UniProtKB:Q6IFG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056794 name: OR6B2_HUMAN def: "Olfactory receptor 6B2" [UniProtKB:Q6IFH4] synonym: "Olfactory receptor OR2-1" EXACT [UniProtKB:Q6IFH4] xref: EMBL:BAC05889.1 xref: EMBL:DAA04686.1 xref: UniProtKB:Q6IFH4 xref: UniProtKB:Q8NGW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019196 ! OR6B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056795 name: Q6IFH9_HUMAN def: "Olfactory receptor OR11-26" [UniProtKB:Q6IFH9] xref: EMBL:DAA04681.1 xref: UniProtKB:Q6IFH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056796 name: Q6IFI0_HUMAN def: "Olfactory receptor OR11-22" [UniProtKB:Q6IFI0] xref: EMBL:DAA04680.1 xref: UniProtKB:Q6IFI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056797 name: Q6IFI1_HUMAN def: "Olfactory receptor OR11-23 (Olfactory receptor, family 51, subfamily F, member 2)" [UniProtKB:Q6IFI1] xref: EMBL:AAI36878.1 xref: EMBL:DAA04679.1 xref: EMBL:EAW68826.1 xref: UniProtKB:Q6IFI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021175 ! OR51F2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056798 name: Q6IFI5_HUMAN def: "Olfactory receptor OR9-17" [UniProtKB:Q6IFI5] xref: EMBL:DAA04675.1 xref: UniProtKB:Q6IFI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056799 name: Q6IFI7_HUMAN def: "Olfactory receptor OR11-47" [UniProtKB:Q6IFI7] xref: EMBL:DAA04673.1 xref: UniProtKB:Q6IFI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056800 name: Q6IFI8_HUMAN def: "Olfactory receptor OR6-11" [UniProtKB:Q6IFI8] xref: EMBL:DAA04672.1 xref: UniProtKB:Q6IFI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056801 name: Q6IFJ4_HUMAN def: "Olfactory receptor OR19-6" [UniProtKB:Q6IFJ4] xref: EMBL:DAA04666.1 xref: UniProtKB:Q6IFJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056802 name: Q6IFJ8_HUMAN def: "Olfactory receptor OR11-12" [UniProtKB:Q6IFJ8] xref: EMBL:DAA04662.1 xref: UniProtKB:Q6IFJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056803 name: Q6IFK7_HUMAN def: "Olfactory receptor OR11-49" [UniProtKB:Q6IFK7] xref: EMBL:DAA04653.1 xref: UniProtKB:Q6IFK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056804 name: Q6IFK8_HUMAN def: "Olfactory receptor OR11-74" [UniProtKB:Q6IFK8] xref: EMBL:DAA04652.1 xref: UniProtKB:Q6IFK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056805 name: Q6IFK9_HUMAN def: "Olfactory receptor OR11-50" [UniProtKB:Q6IFK9] xref: EMBL:DAA04651.1 xref: UniProtKB:Q6IFK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056806 name: Q6IFL0_HUMAN def: "Olfactory receptor OR11-75" [UniProtKB:Q6IFL0] xref: EMBL:DAA04650.1 xref: UniProtKB:Q6IFL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056807 name: Q6IFL1_HUMAN def: "Olfactory receptor OR9-15 (Olfactory receptor, family 13, subfamily D, member 1)" [UniProtKB:Q6IFL1] xref: EMBL:CAH73577.1 xref: EMBL:DAA04649.1 xref: UniProtKB:Q6IFL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021176 ! OR13D1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056808 name: Q6IFL9_HUMAN def: "Olfactory receptor OR17-8" [UniProtKB:Q6IFL9] xref: EMBL:DAA04641.1 xref: UniProtKB:Q6IFL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056809 name: Q6IFM6_HUMAN def: "Olfactory receptor OR17-22 (Olfactory receptor, family 3, subfamily A, member 3)" [UniProtKB:Q6IFM6] xref: EMBL:AAH69415.1 xref: EMBL:DAA04634.1 xref: UniProtKB:Q6IFM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021177 ! OR3A3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056810 name: Q6IFM8_HUMAN def: "Olfactory receptor OR9-30" [UniProtKB:Q6IFM8] xref: EMBL:DAA04632.1 xref: UniProtKB:Q6IFM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056811 name: Q6IFN2_HUMAN def: "Olfactory receptor OR9-27" [UniProtKB:Q6IFN2] xref: EMBL:DAA04628.1 xref: UniProtKB:Q6IFN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056812 name: Q6IFN7_HUMAN def: "Olfactory receptor OR6-36 (Olfactory receptor, family 2, subfamily H, member 2)" [UniProtKB:Q6IFN7] xref: EMBL:CAQ06607.1 xref: EMBL:CAQ07769.1 xref: EMBL:CAQ10427.1 xref: EMBL:DAA04623.1 xref: UniProtKB:Q6IFN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019098 ! OR2H2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056813 name: Q6IFP3_HUMAN def: "Olfactory receptor, family 4, subfamily F, member 29" [UniProtKB:Q6IFP3] synonym: "Olfactory receptor OR7-21" EXACT [UniProtKB:Q6IFP3] xref: EMBL:AAI37569.1 xref: EMBL:DAA04617.1 xref: UniProtKB:Q6IFP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019154 ! OR4F29_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056814 name: Q6IFP9_HUMAN def: "Olfactory receptor OR19-22" [UniProtKB:Q6IFP9] xref: EMBL:DAA04611.1 xref: UniProtKB:Q6IFP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056815 name: Q6IFR1_HUMAN def: "Olfactory receptor OR11-87" [UniProtKB:Q6IFR1] xref: EMBL:DAA04599.1 xref: UniProtKB:Q6IFR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056816 name: Q6IFR4_HUMAN def: "Olfactory receptor OR1-21" [UniProtKB:Q6IFR4] xref: EMBL:DAA04596.1 xref: UniProtKB:Q6IFR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056817 name: Q6IFR5_HUMAN def: "Olfactory receptor OR1-18" [UniProtKB:Q6IFR5] xref: EMBL:DAA04595.1 xref: UniProtKB:Q6IFR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056818 name: Q6IFS1_HUMAN def: "Olfactory receptor OR1-8" [UniProtKB:Q6IFS1] xref: EMBL:DAA04589.1 xref: UniProtKB:Q6IFS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056819 name: CAPR2_HUMAN def: "Caprin-2" [UniProtKB:Q6IMN6] synonym: "C1q domain-containing protein 1" EXACT [UniProtKB:Q6IMN6] synonym: "Cytoplasmic activation/proliferation-associated protein 2" EXACT [UniProtKB:Q6IMN6] synonym: "EEG-1" EXACT [UniProtKB:Q6IMN6] synonym: "Gastric cancer multidrug resistance-associated protein" EXACT [UniProtKB:Q6IMN6] xref: EMBL:AAH66295.1 xref: EMBL:AAI11008.1 xref: EMBL:AAI17673.1 xref: EMBL:AAK83153.1 xref: EMBL:AAL71549.1 xref: EMBL:AAL71550.1 xref: EMBL:BAB13830.1 xref: EMBL:BAB15398.1 xref: EMBL:CAD98004.1 xref: EMBL:DAA01119.1 xref: EMBL:DAA01120.1 xref: UniProtKB:Q149P7 xref: UniProtKB:Q6IMN5 xref: UniProtKB:Q6IMN6 xref: UniProtKB:Q7Z371 xref: UniProtKB:Q8TE70 xref: UniProtKB:Q8TE71 xref: UniProtKB:Q96RN6 xref: UniProtKB:Q9H667 xref: UniProtKB:Q9HAL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017226 ! CAPRIN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: transforms_into CCO:B0064063 ! CAPR2_HUMAN-Phosphoserine547 relationship: transforms_into CCO:B0064064 ! CAPR2_HUMAN-Phosphoserine554 relationship: transforms_into CCO:B0064065 ! CAPR2_HUMAN-Phosphothreonine560 relationship: transforms_into CCO:B0064066 ! CAPR2_HUMAN-Phosphotyrosine924 [Term] id: CCO:B0056820 name: Q6IPL9_HUMAN def: "HMGA1 protein" [UniProtKB:Q6IPL9] xref: EMBL:AAH71863.1 xref: UniProtKB:Q6IPL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018142 ! HMGA1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056821 name: Q6IPM3_HUMAN def: "Actin-related protein 2/3 complex subunit 5" [UniProtKB:Q6IPM3] xref: EMBL:AAH71857.1 xref: UniProtKB:Q6IPM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0056822 name: TBC3C_HUMAN def: "TBC1 domain family member 3C/3D" [UniProtKB:Q6IPX1] xref: EMBL:AAH71680.1 xref: UniProtKB:Q6IPX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020175 ! TBC1D3C_human relationship: encoded_by CCO:G0020176 ! TBC1D3D_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056823 name: TCAL6_HUMAN def: "Transcription elongation factor A protein-like 6" [UniProtKB:Q6IPX3] synonym: "TCEA-like protein 6" EXACT [UniProtKB:Q6IPX3] synonym: "Transcription elongation factor S-II protein-like 6" EXACT [UniProtKB:Q6IPX3] xref: EMBL:AAH71675.1 xref: EMBL:CAI42012.1 xref: UniProtKB:Q5H9J8 xref: UniProtKB:Q6IPX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020205 ! TCEAL6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071256 ! TCAL6_HUMAN-Phosphoserine125 [Term] id: CCO:B0056824 name: Q6IQ01_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q6IQ01] xref: EMBL:AAH71639.1 xref: UniProtKB:Q6IQ01 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056825 name: ZN770_HUMAN def: "Zinc finger protein 770" [UniProtKB:Q6IQ21] xref: EMBL:AAH71603.1 xref: EMBL:BAA91274.1 xref: EMBL:BAD18579.1 xref: UniProtKB:Q6IQ21 xref: UniProtKB:Q6ZMZ6 xref: UniProtKB:Q9NWV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020929 ! ZNF770_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056826 name: RAB12_HUMAN def: "Putative Ras-related protein Rab-12" [UniProtKB:Q6IQ22] xref: EMBL:AAH71600.2 xref: EMBL:AAH98407.1 xref: EMBL:EAX01616.1 xref: UniProtKB:A6NEF5 xref: UniProtKB:Q4KMQ3 xref: UniProtKB:Q6IQ22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019571 ! RAB12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069662 ! RAB12_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0069663 ! RAB12_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0069664 ! RAB12_HUMAN-Phosphoserine106 [Term] id: CCO:B0056827 name: ADNP2_HUMAN def: "ADNP homeobox protein 2" [UniProtKB:Q6IQ32] synonym: "Zinc finger protein 508" EXACT [UniProtKB:Q6IQ32] xref: EMBL:AAH71589.1 xref: EMBL:BAA74886.2 xref: EMBL:BAB14180.1 xref: UniProtKB:O94943 xref: UniProtKB:Q6IQ32 xref: UniProtKB:Q9H9P3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016919 ! ADNP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056828 name: GRHL2_HUMAN def: "Grainyhead-like protein 2 homolog" [UniProtKB:Q6ISB3] synonym: "Brother of mammalian grainyhead" EXACT [UniProtKB:Q6ISB3] synonym: "Transcription factor CP2-like 3" EXACT [UniProtKB:Q6ISB3] xref: EMBL:AAH69618.1 xref: EMBL:AAH69633.1 xref: EMBL:AAH69638.1 xref: EMBL:BAB14699.1 xref: UniProtKB:Q6ISB3 xref: UniProtKB:Q6NT03 xref: UniProtKB:Q9H8B8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018058 ! GRHL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056829 name: Q6ISP1_HUMAN def: "CIB3 protein" [UniProtKB:Q6ISP1] synonym: "Calcium and integrin binding family member 3, isoform CRA_c" EXACT [UniProtKB:Q6ISP1] xref: EMBL:AAH69428.1 xref: EMBL:EAW84535.1 xref: UniProtKB:Q6ISP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021178 ! CIB3_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0056830 name: ZN425_HUMAN def: "Zinc finger protein 425" [UniProtKB:Q6IV72] xref: EMBL:AAT40438.1 xref: UniProtKB:Q6IV72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020744 ! ZNF425_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056831 name: Q6JUT2_HUMAN def: "Toll-like receptor adapter molecule 2 (TICAM-2) (Putative NF-kappa-B- activating protein 502)." [UniProtKB:Q6JUT2] xref: EMBL:AAQ97430.1 xref: EMBL:AAQ97433.1 xref: EMBL:EAW48961.1 xref: UniProtKB:Q6JUT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021179 ! TIRAP3_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056832 name: Q6KAL7_HUMAN def: "Uncharacterized protein C20orf157." [UniProtKB:Q6KAL7] xref: EMBL:CAB42849.1 xref: UniProtKB:Q6KAL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021180 ! C20orf157_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056833 name: Q6KAV0_HUMAN def: "cDNA FLJ46519 fis, clone THYMU3033649, highly similar to T-cell surface glycoprotein CD3 zeta chain" [UniProtKB:Q6KAV0] xref: EMBL:BAC87407.1 xref: UniProtKB:Q6KAV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0056834 name: GDF6_HUMAN def: "Growth/differentiation factor 6 precursor" [UniProtKB:Q6KF10] synonym: "GDF-6" EXACT [UniProtKB:Q6KF10] synonym: "Growth/differentiation factor 16" EXACT [UniProtKB:Q6KF10] xref: EMBL:AAH43222.1 xref: EMBL:CAD60934.1 xref: UniProtKB:Q6KF10 xref: UniProtKB:Q6PI58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017906 ! GDF6_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001714 ! activin receptor signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0056835 name: Q6KF62_HUMAN def: "Caspase 10" [UniProtKB:Q6KF62] synonym: "Caspase 10, apoptosis-related cysteine peptidase, isoform CRA_b" EXACT [UniProtKB:Q6KF62] xref: EMBL:CAD32372.1 xref: EMBL:EAW70248.1 xref: UniProtKB:Q6KF62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017240 ! CASP10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056836 name: Q6KF63_HUMAN def: "Caspase 10" [UniProtKB:Q6KF63] xref: EMBL:CAD32371.1 xref: UniProtKB:Q6KF63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017240 ! CASP10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056837 name: Q6L9M1_HUMAN def: "Peroxisome proliferator-activated receptor gamma 1" [UniProtKB:Q6L9M1] synonym: "Peroxisome proliferator-activated receptor" EXACT [UniProtKB:Q6L9M1] xref: EMBL:BAD20647.1 xref: EMBL:BAD34540.1 xref: UniProtKB:Q6L9M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005362 ! PPARG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056838 name: Q6LAI4_HUMAN def: "Sperm protein" [UniProtKB:Q6LAI4] xref: EMBL:CAC79990.1 xref: UniProtKB:Q6LAI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0056839 name: Q6LEE7_HUMAN def: "Chemokine-like receptor 1" [UniProtKB:Q6LEE7] xref: EMBL:AAQ62778.1 xref: UniProtKB:Q6LEE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017394 ! CMKLR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056840 name: Q6MZH2_HUMAN def: "Putative uncharacterized protein DKFZp686J07132" [UniProtKB:Q6MZH2] xref: EMBL:CAE46061.1 xref: UniProtKB:Q6MZH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021181 ! DKFZp686J07132_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056841 name: Q6MZK5_HUMAN def: "Putative uncharacterized protein DKFZp686I1383" [UniProtKB:Q6MZK5] xref: EMBL:CAE46025.1 xref: UniProtKB:Q6MZK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021182 ! DKFZp686I1383_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056842 name: R7BP_HUMAN def: "Regulator of G-protein signaling 7-binding protein" [UniProtKB:Q6MZT1] synonym: "R7 family-binding protein" EXACT [UniProtKB:Q6MZT1] xref: EMBL:CAE45947.1 xref: UniProtKB:Q6MZT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019569 ! RGS7BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0056843 name: Q6MZT2_HUMAN def: "Putative uncharacterized protein DKFZp686D1354" [UniProtKB:Q6MZT2] xref: EMBL:CAE45946.1 xref: UniProtKB:Q6MZT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021185 ! DKFZp686D1354_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0056844 name: Q6N011_HUMAN def: "Putative uncharacterized protein DKFZp686C24207" [UniProtKB:Q6N011] xref: EMBL:CAE45862.1 xref: UniProtKB:Q6N011 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021186 ! DKFZp686C24207_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056845 name: Q6N016_HUMAN def: "Putative uncharacterized protein DKFZp686O17118" [UniProtKB:Q6N016] xref: EMBL:CAE45857.1 xref: UniProtKB:Q6N016 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021187 ! DKFZp686O17118_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056846 name: Z280D_HUMAN def: "Zinc finger protein 280D" [UniProtKB:Q6N043] synonym: "Suppressor of hairy wing homolog 4" EXACT [UniProtKB:Q6N043] xref: EMBL:BAA90940.1 xref: EMBL:BAB13410.1 xref: EMBL:CAB66569.1 xref: EMBL:CAE45785.1 xref: EMBL:CAE45827.1 xref: EMBL:CAE46003.1 xref: UniProtKB:Q6MZM6 xref: UniProtKB:Q6N043 xref: UniProtKB:Q6N085 xref: UniProtKB:Q9H0U5 xref: UniProtKB:Q9HCI8 xref: UniProtKB:Q9NXS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020517 ! ZNF280D_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071937 ! Z280D_HUMAN-Phosphoserine530 relationship: transforms_into CCO:B0071938 ! Z280D_HUMAN-Phosphoserine545 [Term] id: CCO:B0056847 name: ZNP12_HUMAN def: "Zinc finger protein ZnFP12" [UniProtKB:Q6N045] xref: EMBL:CAE45825.1 xref: UniProtKB:Q6N045 xref: UniProtKB:Q7M4M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056848 name: NARGL_HUMAN def: "NMDA receptor-regulated 1-like protein" [UniProtKB:Q6N069] synonym: "NARG1-like protein" EXACT [UniProtKB:Q6N069] xref: EMBL:AAH32318.1 xref: EMBL:AAH64592.1 xref: EMBL:BAC04980.1 xref: EMBL:CAE45801.1 xref: EMBL:CAH71511.1 xref: EMBL:CAH73370.1 xref: EMBL:CAI16619.1 xref: UniProtKB:Q5VSP9 xref: UniProtKB:Q6N069 xref: UniProtKB:Q6P2D5 xref: UniProtKB:Q8N5J3 xref: UniProtKB:Q8N870 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018721 ! NARG1L_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0005784 ! ribosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0056849 name: Q6N0A5_HUMAN def: "Putative uncharacterized protein DKFZp686I13174" [UniProtKB:Q6N0A5] xref: EMBL:CAE45715.1 xref: UniProtKB:Q6N0A5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021189 ! DKFZp686I13174_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056850 name: Q6NSD8_HUMAN def: "FGA protein" [UniProtKB:Q6NSD8] xref: EMBL:AAH70246.1 xref: UniProtKB:Q6NSD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017805 ! FGA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056851 name: Q6NSH2_HUMAN def: "ZNF28 protein" [UniProtKB:Q6NSH2] xref: EMBL:AAH70146.1 xref: UniProtKB:Q6NSH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020967 ! ZNF28_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056852 name: Q6NSM0_HUMAN def: "NR1D2 protein" [UniProtKB:Q6NSM0] xref: EMBL:AAH70035.1 xref: UniProtKB:Q6NSM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018850 ! NR1D2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056853 name: NANP8_HUMAN def: "Homeobox protein NANOGP8" [UniProtKB:Q6NSW7] xref: EMBL:AAH69807.1 xref: EMBL:AAH98275.1 xref: EMBL:AAH99704.1 xref: UniProtKB:Q6NSW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018719 ! NANOGP8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056854 name: Q6NSZ5_HUMAN def: "NR1I3 protein" [UniProtKB:Q6NSZ5] synonym: "Nuclear receptor subfamily 1, group I, member 3, isoform CRA_c" EXACT [UniProtKB:Q6NSZ5] xref: EMBL:AAH69651.1 xref: EMBL:EAW52610.1 xref: UniProtKB:Q6NSZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018855 ! NR1I3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056855 name: ZN498_HUMAN def: "Zinc finger protein 498" [UniProtKB:Q6NSZ9] synonym: "Zinc finger and SCAN domain-containing protein 25" EXACT [UniProtKB:Q6NSZ9] xref: EMBL:AAH69644.2 xref: EMBL:AAH74902.3 xref: EMBL:AAH74903.3 xref: EMBL:AAH89402.1 xref: EMBL:AAI14574.1 xref: EMBL:AAI14942.1 xref: EMBL:BAD18712.1 xref: EMBL:CAE45839.1 xref: EMBL:EAL23869.1 xref: EMBL:EAW76643.1 xref: UniProtKB:A4D290 xref: UniProtKB:Q14C82 xref: UniProtKB:Q14C99 xref: UniProtKB:Q5EBM9 xref: UniProtKB:Q6DJZ0 xref: UniProtKB:Q6N032 xref: UniProtKB:Q6NSZ9 xref: UniProtKB:Q6ZML3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020780 ! ZNF498_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056856 name: TIGD7_HUMAN def: "Tigger transposable element-derived protein 7" [UniProtKB:Q6NT04] xref: EMBL:AAH69623.1 xref: EMBL:AAH69632.1 xref: EMBL:AAK34940.1 xref: UniProtKB:Q6NT04 xref: UniProtKB:Q9BXZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020271 ! TIGD7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056857 name: Q6NT51_HUMAN def: "BARX homeobox 2" [UniProtKB:Q6NT51] synonym: "BarH-like homeobox 2" EXACT [UniProtKB:Q6NT51] xref: EMBL:AAH69378.1 xref: EMBL:AAI11433.1 xref: EMBL:AAI11573.1 xref: EMBL:EAW67743.1 xref: UniProtKB:Q6NT51 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021190 ! BARX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056858 name: HMBX1_HUMAN def: "Homeobox-containing protein 1" [UniProtKB:Q6NT76] xref: EMBL:AAH09259.2 xref: EMBL:AAH69242.1 xref: EMBL:AAS76643.1 xref: EMBL:AAZ81565.1 xref: EMBL:BAB15099.1 xref: UniProtKB:Q3Y6P1 xref: UniProtKB:Q6NT76 xref: UniProtKB:Q96GS5 xref: UniProtKB:Q9H701 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018139 ! HMBOX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056859 name: Q6NTB5_HUMAN def: "OR5V1 protein" [UniProtKB:Q6NTB5] synonym: "Olfactory receptor, family 5, subfamily V, member 1" EXACT [UniProtKB:Q6NTB5] xref: EMBL:AAH69149.1 xref: EMBL:CAQ07996.1 xref: UniProtKB:Q6NTB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019194 ! OR5V1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056860 name: Q6NUP5_HUMAN def: "Angiotensin II receptor, type 1" [UniProtKB:Q6NUP5] xref: EMBL:AAH68494.1 xref: UniProtKB:Q6NUP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016933 ! AGTR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_function CCO:F0001289 ! bradykinin receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056861 name: Q6NUQ6_HUMAN def: "RAPGEF3 protein" [UniProtKB:Q6NUQ6] xref: EMBL:AAH68477.1 xref: UniProtKB:Q6NUQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019786 ! RAPGEF3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056862 name: GP153_HUMAN def: "Probable G-protein coupled receptor 153" [UniProtKB:Q6NV75] synonym: "G-protein coupled receptor PGR1" EXACT [UniProtKB:Q6NV75] xref: EMBL:AAH68275.1 xref: EMBL:AAO85041.1 xref: EMBL:CAH10674.1 xref: EMBL:CAI19434.1 xref: UniProtKB:Q5TGR5 xref: UniProtKB:Q6AHW8 xref: UniProtKB:Q6NV75 xref: UniProtKB:Q86SP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017977 ! GPR153_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056863 name: RGMB_HUMAN def: "RGM domain family member B precursor" [UniProtKB:Q6NW40] xref: EMBL:AAH67736.1 xref: EMBL:BAC11268.1 xref: UniProtKB:Q6NW40 xref: UniProtKB:Q8NC92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019696 ! RGMB_human relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001959 ! anchored to plasma membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0056864 name: Q6NWR3_HUMAN def: "G protein-coupled receptor 83" [UniProtKB:Q6NWR3] xref: EMBL:AAH67474.1 xref: UniProtKB:Q6NWR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018035 ! GPR83_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056865 name: ZN774_HUMAN def: "Zinc finger protein 774" [UniProtKB:Q6NX45] xref: EMBL:AAH67279.1 xref: UniProtKB:Q6NX45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020931 ! ZNF774_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056866 name: ZN544_HUMAN def: "Zinc finger protein 544" [UniProtKB:Q6NX49] xref: EMBL:AAC01956.1 xref: EMBL:AAH67271.1 xref: UniProtKB:Q6NX49 xref: UniProtKB:Q9UEX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020807 ! ZNF544_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056867 name: Q6NX52_HUMAN def: "ARHGEF1 protein" [UniProtKB:Q6NX52] synonym: "Rho guanine nucleotide exchange factor (GEF) 1, isoform CRA_g" EXACT [UniProtKB:Q6NX52] xref: EMBL:AAH67262.1 xref: EMBL:EAW57084.1 xref: UniProtKB:Q6NX52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004090 ! ARHGEF1_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056868 name: IPP2M_HUMAN def: "Putative protein phosphatase inhibitor 2-like protein 3" [UniProtKB:Q6NXS1] synonym: "Protein phosphatase 1, regulatory subunit 2 pseudogene 3" EXACT [UniProtKB:Q6NXS1] xref: EMBL:AAH66922.1 xref: UniProtKB:Q6NXS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018301 ! PPP1R2P3_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0067126 ! IPP2M_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0067127 ! IPP2M_HUMAN-Phosphoserine122 [Term] id: CCO:B0056869 name: Q6NXS2_HUMAN def: "PPP1R2 protein" [UniProtKB:Q6NXS2] xref: EMBL:AAH66921.1 xref: UniProtKB:Q6NXS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018302 ! PPP1R2_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0056870 name: Q6NXU0_HUMAN def: "Nuclear receptor subfamily 4, group A, member 2" [UniProtKB:Q6NXU0] synonym: "cDNA FLJ75035, highly similar to Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), transcript variant 4, mRNA" EXACT [UniProtKB:Q6NXU0] xref: EMBL:AAH66890.1 xref: EMBL:BAF84145.1 xref: UniProtKB:Q6NXU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018861 ! NR4A2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056871 name: JMJD6_HUMAN def: "Histone arginine demethylase JMJD6" [UniProtKB:Q6NYC1] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q6NYC1] synonym: "JmjC domain-containing protein 6" EXACT [UniProtKB:Q6NYC1] synonym: "Jumonji domain-containing protein 6" EXACT [UniProtKB:Q6NYC1] synonym: "Phosphatidylserine receptor" EXACT [UniProtKB:Q6NYC1] synonym: "Protein PTDSR" EXACT [UniProtKB:Q6NYC1] xref: EMBL:AAH47003.1 xref: EMBL:AAH66654.1 xref: EMBL:BAA25511.1 xref: EMBL:BAC16755.1 xref: UniProtKB:Q6NYC1 xref: UniProtKB:Q86VY0 xref: UniProtKB:Q8IUM5 xref: UniProtKB:Q9Y4E2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018367 ! JMJD6_human relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0005239 ! histone demethylase activity (H3-R2 specific) relationship: has_function CCO:F0005242 ! histone demethylase activity (H4-R3 specific) relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0056872 name: Q6NZ33_HUMAN def: "RAB2B protein" [UniProtKB:Q6NZ33] synonym: "cDNA FLJ55078, highly similar to Ras-related protein Rab-2B" EXACT [UniProtKB:Q6NZ33] xref: EMBL:AAH66366.1 xref: EMBL:BAG58820.1 xref: UniProtKB:Q6NZ33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019586 ! RAB2B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056873 name: PTRF_HUMAN def: "Polymerase I and transcript release factor" [UniProtKB:Q6NZI2] xref: EMBL:AAC63404.1 xref: EMBL:AAG27093.1 xref: EMBL:AAH04295.1 xref: EMBL:AAH08849.1 xref: EMBL:AAH66123.1 xref: EMBL:AAH73759.1 xref: UniProtKB:O00535 xref: UniProtKB:Q6GMY1 xref: UniProtKB:Q6NZI2 xref: UniProtKB:Q96H74 xref: UniProtKB:Q9BT85 xref: UniProtKB:Q9HAP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019555 ! PTRF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0069606 ! PTRF_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0069607 ! PTRF_HUMAN-Phosphoserine40 relationship: transforms_into CCO:B0069608 ! PTRF_HUMAN-Phosphotyrosine156 relationship: transforms_into CCO:B0069609 ! PTRF_HUMAN-Phosphoserine167 relationship: transforms_into CCO:B0069610 ! PTRF_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0069611 ! PTRF_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0069612 ! PTRF_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0069613 ! PTRF_HUMAN-Phosphothreonine302 relationship: transforms_into CCO:B0069614 ! PTRF_HUMAN-Phosphotyrosine308 relationship: transforms_into CCO:B0069615 ! PTRF_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0069616 ! PTRF_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0069617 ! PTRF_HUMAN-Phosphothreonine376 relationship: transforms_into CCO:B0069618 ! PTRF_HUMAN-Phosphoserine379 relationship: transforms_into CCO:B0069619 ! PTRF_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0069620 ! PTRF_HUMAN-Phosphoserine389 [Term] id: CCO:B0056874 name: BORG3_HUMAN def: "Cdc42 effector protein 5" [UniProtKB:Q6NZY7] synonym: "Binder of Rho GTPases 3" EXACT [UniProtKB:Q6NZY7] xref: EMBL:AAH24327.1 xref: EMBL:AAH65910.1 xref: UniProtKB:Q6NZY7 xref: UniProtKB:Q8TB51 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017173 ! CDC42EP5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003532 ! GTP-Rho binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001331 ! positive regulation of actin filament polymerization relationship: participates_in CCO:P0001391 ! positive regulation of pseudopodium formation [Term] id: CCO:B0056875 name: Q6P051_HUMAN def: "SIX6 protein" [UniProtKB:Q6P051] xref: EMBL:AAH65831.1 xref: UniProtKB:Q6P051 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019925 ! SIX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056876 name: MAST2_HUMAN def: "Microtubule-associated serine/threonine-protein kinase 2" [UniProtKB:Q6P0Q8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q6P0Q8] xref: EMBL:AAH15816.2 xref: EMBL:AAH65499.1 xref: EMBL:BAA34527.2 xref: EMBL:BAB40778.1 xref: EMBL:CAD38775.1 xref: EMBL:CAH73244.1 xref: EMBL:CAH73245.1 xref: EMBL:CAI16217.1 xref: EMBL:CAI16562.1 xref: EMBL:CAI16563.1 xref: EMBL:CAI21705.1 xref: EMBL:CAI21706.1 xref: UniProtKB:O94899 xref: UniProtKB:Q5VT07 xref: UniProtKB:Q5VT08 xref: UniProtKB:Q6P0Q8 xref: UniProtKB:Q7LGC4 xref: UniProtKB:Q8NDG1 xref: UniProtKB:Q96B94 xref: UniProtKB:Q9BYE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008379 ! MAST2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017673 ! mast2-pclkc-2 physical interaction relationship: participates_in CCO:I0017862 ! mast2-pclkc-1 physical interaction relationship: participates_in CCO:I0018174 ! mast2-pclkc-4 colocalization relationship: participates_in CCO:I0019490 ! mast2-pclkc-3 physical interaction relationship: participates_in CCO:P0002267 ! regulation of interleukin-12 biosynthetic process relationship: transforms_into CCO:B0067998 ! MAST2_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0067999 ! MAST2_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0068000 ! MAST2_HUMAN-Phosphoserine900 relationship: transforms_into CCO:B0068001 ! MAST2_HUMAN-Phosphoserine1503 relationship: transforms_into CCO:B0068002 ! MAST2_HUMAN-Phosphothreonine1508 [Term] id: CCO:B0056877 name: Q6P0Y2_HUMAN def: "FOXH1 protein" [UniProtKB:Q6P0Y2] xref: EMBL:AAH65377.1 xref: UniProtKB:Q6P0Y2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017822 ! FOXH1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056878 name: Q6P1A4_HUMAN def: "ZNF33B protein" [UniProtKB:Q6P1A4] xref: EMBL:AAH65181.1 xref: UniProtKB:Q6P1A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020713 ! ZNF33B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056879 name: ZN343_HUMAN def: "Zinc finger protein 343" [UniProtKB:Q6P1L6] xref: EMBL:AAH02897.1 xref: EMBL:AAH11862.2 xref: EMBL:AAH65009.1 xref: EMBL:BAB71000.1 xref: EMBL:BAC04892.1 xref: EMBL:CAB46713.2 xref: EMBL:CAI22572.1 xref: EMBL:CAI22573.1 xref: EMBL:CAI22574.1 xref: UniProtKB:Q5JXU8 xref: UniProtKB:Q5JXU9 xref: UniProtKB:Q6P1L6 xref: UniProtKB:Q8N8F2 xref: UniProtKB:Q96EX8 xref: UniProtKB:Q96NA5 xref: UniProtKB:Q9BQB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020715 ! ZNF343_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056880 name: C2D1A_HUMAN def: "Coiled-coil and C2 domain-containing protein 1A" [UniProtKB:Q6P1N0] synonym: "Five repressor element under dual repression-binding protein 1" EXACT [UniProtKB:Q6P1N0] synonym: "FRE under dual repression-binding protein 1" EXACT [UniProtKB:Q6P1N0] synonym: "Freud-1" EXACT [UniProtKB:Q6P1N0] synonym: "Putative NF-kappa-B-activating protein 023N" EXACT [UniProtKB:Q6P1N0] xref: EMBL:AAH48345.1 xref: EMBL:AAH64981.1 xref: EMBL:AAN04488.1 xref: EMBL:BAA91029.1 xref: EMBL:BAB15464.1 xref: EMBL:BAC77355.1 xref: UniProtKB:Q6P1N0 xref: UniProtKB:Q7Z435 xref: UniProtKB:Q86XV0 xref: UniProtKB:Q8NF89 xref: UniProtKB:Q9H603 xref: UniProtKB:Q9NXI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017195 ! CC2D1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0064019 ! C2D1A_HUMAN-Phosphotyrosine207 relationship: transforms_into CCO:B0064020 ! C2D1A_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0064021 ! C2D1A_HUMAN-Phosphoserine455 [Term] id: CCO:B0056881 name: TAF2_HUMAN def: "Transcription initiation factor TFIID subunit 2" [UniProtKB:Q6P1X5] synonym: "150 kDa cofactor of initiator function" EXACT [UniProtKB:Q6P1X5] synonym: "RNA polymerase II TBP-associated factor subunit B" EXACT [UniProtKB:Q6P1X5] synonym: "TAFII-150" EXACT [UniProtKB:Q6P1X5] synonym: "TAFII150" EXACT [UniProtKB:Q6P1X5] synonym: "TBP-associated factor 150 kDa" EXACT [UniProtKB:Q6P1X5] synonym: "Transcription initiation factor TFIID 150 kDa subunit" EXACT [UniProtKB:Q6P1X5] xref: EMBL:AAC02966.1 xref: EMBL:AAC13540.1 xref: EMBL:AAC68502.1 xref: EMBL:AAH35673.1 xref: EMBL:AAH47732.1 xref: EMBL:AAH64830.1 xref: UniProtKB:O43487 xref: UniProtKB:O43604 xref: UniProtKB:O60668 xref: UniProtKB:Q6P1X5 xref: UniProtKB:Q86WW7 xref: UniProtKB:Q8IWK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020133 ! TAF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071087 ! TAF2_HUMAN-Phosphoserine1194 relationship: transforms_into CCO:B0071088 ! TAF2_HUMAN-Phosphoserine1196 relationship: transforms_into CCO:B0071089 ! TAF2_HUMAN-Phosphoserine1198 [Term] id: CCO:B0056882 name: ZN529_HUMAN def: "Zinc finger protein 529" [UniProtKB:Q6P280] xref: EMBL:AAH64690.1 xref: EMBL:BAB13441.1 xref: EMBL:BAB15068.1 xref: UniProtKB:Q6P280 xref: UniProtKB:Q9H731 xref: UniProtKB:Q9HCF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020800 ! ZNF529_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056883 name: ZFP1_HUMAN def: "Zinc finger protein 1 homolog" [UniProtKB:Q6P2D0] synonym: "Zfp-1" EXACT [UniProtKB:Q6P2D0] xref: EMBL:AAH33774.1 xref: EMBL:AAH64604.1 xref: EMBL:BAC04417.1 xref: UniProtKB:Q6P2D0 xref: UniProtKB:Q8N188 xref: UniProtKB:Q8N9F9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020586 ! ZFP1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056884 name: Q6P2E6_HUMAN def: "ZNF333 protein" [UniProtKB:Q6P2E6] synonym: "cDNA FLJ78332, highly similar to Homo sapiens zinc finger protein 333, mRNA" EXACT [UniProtKB:Q6P2E6] xref: EMBL:AAH64571.1 xref: EMBL:BAF84160.1 xref: UniProtKB:Q6P2E6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020708 ! ZNF333_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056885 name: Q6P2H9_HUMAN def: "CD40 protein" [UniProtKB:Q6P2H9] xref: EMBL:AAH64518.1 xref: UniProtKB:Q6P2H9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020320 ! CD40_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056886 name: Q6P2M6_HUMAN def: "Vasoactive intestinal peptide receptor 1" [UniProtKB:Q6P2M6] xref: EMBL:AAH64424.1 xref: UniProtKB:Q6P2M6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020450 ! VIPR1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056887 name: Q6P2R4_HUMAN xref: UniProtKB:Q6P2R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056888 name: Z585A_HUMAN def: "Zinc finger protein 585A" [UniProtKB:Q6P3V2] xref: EMBL:AAH63820.1 xref: EMBL:BAB71174.1 xref: EMBL:BAB85057.1 xref: UniProtKB:Q6P3V2 xref: UniProtKB:Q8TE95 xref: UniProtKB:Q96MV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020531 ! ZNF585A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071945 ! Z585A_HUMAN-Phosphoserine118 [Term] id: CCO:B0056889 name: RHGBA_HUMAN def: "Rho GTPase-activating protein 11A" [UniProtKB:Q6P4F7] synonym: "Rho-type GTPase-activating protein 11A" EXACT [UniProtKB:Q6P4F7] xref: EMBL:AAH39563.1 xref: EMBL:AAH63444.1 xref: EMBL:BAA13442.2 xref: UniProtKB:Q6P4F7 xref: UniProtKB:Q6PI96 xref: UniProtKB:Q9Y3S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019729 ! ARHGAP11A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069997 ! RHGBA_HUMAN-Phosphoserine285 relationship: transforms_into CCO:B0069998 ! RHGBA_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0069999 ! RHGBA_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0070000 ! RHGBA_HUMAN-Phosphothreonine323 relationship: transforms_into CCO:B0070001 ! RHGBA_HUMAN-Phosphoserine339 relationship: transforms_into CCO:B0070002 ! RHGBA_HUMAN-Phosphoserine340 relationship: transforms_into CCO:B0070003 ! RHGBA_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0070004 ! RHGBA_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0070005 ! RHGBA_HUMAN-Phosphoserine484 relationship: transforms_into CCO:B0070006 ! RHGBA_HUMAN-Phosphothreonine508 relationship: transforms_into CCO:B0070007 ! RHGBA_HUMAN-Phosphoserine582 relationship: transforms_into CCO:B0070008 ! RHGBA_HUMAN-Phosphoserine585 relationship: transforms_into CCO:B0070009 ! RHGBA_HUMAN-Phosphoserine675 [Term] id: CCO:B0056890 name: Q6P5W7_HUMAN def: "Opsin 3" [UniProtKB:Q6P5W7] synonym: "Opsin 3 (Encephalopsin, panopsin), isoform CRA_a" EXACT [UniProtKB:Q6P5W7] xref: EMBL:AAH62622.1 xref: EMBL:EAW70097.1 xref: UniProtKB:Q6P5W7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019049 ! OPN3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056891 name: Q6P5X8_HUMAN def: "POLM protein" [UniProtKB:Q6P5X8] synonym: "Polymerase (DNA directed), mu, isoform CRA_d" EXACT [UniProtKB:Q6P5X8] xref: EMBL:AAH62590.1 xref: EMBL:EAW61124.1 xref: UniProtKB:Q6P5X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017610 ! POLM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000416 ! DNA nucleotidylexotransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0056892 name: Q6P5Z4_HUMAN def: "Breast cancer anti-estrogen resistance 1" [UniProtKB:Q6P5Z4] xref: EMBL:AAH62556.1 xref: UniProtKB:Q6P5Z4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004146 ! BCAR1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004212 ! protein phosphatase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000477 ! focal adhesion relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0002757 ! nerve growth factor receptor signaling pathway relationship: participates_in CCO:P0002969 ! antigen receptor-mediated signaling pathway relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway [Term] id: CCO:B0056893 name: Q6P6B2_HUMAN def: "LOC100134868 protein" [UniProtKB:Q6P6B2] xref: EMBL:AAH30737.1 xref: EMBL:AAH62357.1 xref: UniProtKB:Q6P6B2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021191 ! LOC100134868_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056894 name: Q6P6D5_HUMAN def: "MYT1 protein" [UniProtKB:Q6P6D5] xref: EMBL:AAH62313.1 xref: UniProtKB:Q6P6D5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005153 ! MYT1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056895 name: ZN530_HUMAN def: "Zinc finger protein 530" [UniProtKB:Q6P9A1] xref: EMBL:AAC24609.1 xref: EMBL:AAH60865.1 xref: EMBL:BAA96032.1 xref: UniProtKB:O43340 xref: UniProtKB:Q6P9A1 xref: UniProtKB:Q9P220 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020801 ! ZNF530_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056896 name: ZN549_HUMAN def: "Zinc finger protein 549" [UniProtKB:Q6P9A3] xref: EMBL:AAH60863.1 xref: EMBL:BAC03834.1 xref: UniProtKB:Q6P9A3 xref: UniProtKB:Q8NAR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020810 ! ZNF549_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056897 name: ZN449_HUMAN def: "Zinc finger protein 449" [UniProtKB:Q6P9G9] synonym: "Zinc finger and SCAN domain-containing protein 19" EXACT [UniProtKB:Q6P9G9] xref: EMBL:AAH60768.1 xref: EMBL:AAH65938.1 xref: EMBL:AAQ16305.1 xref: EMBL:BAB85013.1 xref: EMBL:CAD38639.1 xref: EMBL:CAI39873.1 xref: UniProtKB:Q5JRZ8 xref: UniProtKB:Q6NZX2 xref: UniProtKB:Q6P9G9 xref: UniProtKB:Q8N3Q1 xref: UniProtKB:Q8TED7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020757 ! ZNF449_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056898 name: CNKR3_HUMAN def: "Connector enhancer of kinase suppressor of ras 3" [UniProtKB:Q6P9H4] synonym: "CNKSR family member 3" EXACT [UniProtKB:Q6P9H4] synonym: "Maguin-like protein" EXACT [UniProtKB:Q6P9H4] synonym: "Membrane-associated guanylate kinase-interacting protein-like 1" EXACT [UniProtKB:Q6P9H4] xref: EMBL:AAH60761.1 xref: EMBL:AAQ92306.1 xref: EMBL:AAQ92307.1 xref: EMBL:AAQ92308.1 xref: EMBL:BAB71044.1 xref: EMBL:CAI14545.1 xref: EMBL:EAW47699.1 xref: UniProtKB:Q5SGD5 xref: UniProtKB:Q6P9H4 xref: UniProtKB:Q96N65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017407 ! CNKSR3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0064425 ! CNKR3_HUMAN-Phosphoserine381 [Term] id: CCO:B0056899 name: Q6PCC7_HUMAN def: "ARHGAP8 protein" [UniProtKB:Q6PCC7] xref: EMBL:AAH59382.1 xref: UniProtKB:Q6PCC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005481 ! ARHGAP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056900 name: Q6PD72_HUMAN def: "TBC1D3P2 protein" [UniProtKB:Q6PD72] xref: EMBL:AAH58890.1 xref: UniProtKB:Q6PD72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021192 ! TBC1D3P2_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0056901 name: YS020_HUMAN def: "Zinc finger protein LOC400713" [UniProtKB:Q6PDB4] xref: EMBL:AAH58819.1 xref: UniProtKB:Q6PDB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056902 name: ZN613_HUMAN def: "Zinc finger protein 613" [UniProtKB:Q6PF04] xref: EMBL:AAH57776.1 xref: EMBL:BAB55201.1 xref: UniProtKB:Q6PF04 xref: UniProtKB:Q96SS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020854 ! ZNF613_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056903 name: Q6PFW2_HUMAN def: "Rho guanine nucleotide exchange factor (GEF) 11" [UniProtKB:Q6PFW2] xref: EMBL:AAH57394.1 xref: EMBL:CAH70128.1 xref: EMBL:CAH72939.1 xref: UniProtKB:Q6PFW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017020 ! ARHGEF11_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056904 name: ZN790_HUMAN def: "Zinc finger protein 790" [UniProtKB:Q6PG37] xref: EMBL:AAH57245.1 xref: UniProtKB:Q6PG37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020943 ! ZNF790_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056905 name: Q6PG46_HUMAN def: "AKAP5 protein" [UniProtKB:Q6PG46] xref: EMBL:AAH57229.1 xref: UniProtKB:Q6PG46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016945 ! AKAP5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056906 name: Q6PGP1_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q6PGP1] xref: EMBL:AAH56907.1 xref: UniProtKB:Q6PGP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056907 name: Q6PHZ7_HUMAN def: "NR2C2 protein" [UniProtKB:Q6PHZ7] xref: EMBL:AAH51670.1 xref: UniProtKB:Q6PHZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018857 ! NR2C2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056908 name: CNIH2_HUMAN def: "Protein cornichon homolog 2" [UniProtKB:Q6PI25] synonym: "Cornichon-like protein" EXACT [UniProtKB:Q6PI25] xref: EMBL:AAH47953.1 xref: UniProtKB:Q6PI25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017401 ! CNIH2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056909 name: Q6PI29_HUMAN def: "ANKDD1A protein" [UniProtKB:Q6PI29] xref: EMBL:AAH47607.1 xref: UniProtKB:Q6PI29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016946 ! ANKDD1A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056910 name: Q6PID1_HUMAN def: "ZNF396 protein" [UniProtKB:Q6PID1] xref: EMBL:AAH36765.1 xref: UniProtKB:Q6PID1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020729 ! ZNF396_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056911 name: Q6PID2_HUMAN def: "MGC4836 protein" [UniProtKB:Q6PID2] xref: EMBL:AAH36758.1 xref: UniProtKB:Q6PID2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021193 ! MGC4836_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0056912 name: Q6PIG1_HUMAN def: "ZNF169 protein" [UniProtKB:Q6PIG1] xref: EMBL:AAH35060.2 xref: UniProtKB:Q6PIG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020638 ! ZNF169_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056913 name: Q6PIK3_HUMAN def: "RAB4B protein" [UniProtKB:Q6PIK3] synonym: "HCG1995540, isoform CRA_b (Hcg2044074, isoform cra_d)" EXACT [UniProtKB:Q6PIK3] xref: EMBL:AAH33081.1 xref: EMBL:EAW57005.1 xref: UniProtKB:Q6PIK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019601 ! RAB4B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056914 name: Q6PIT4_HUMAN def: "ZNF573 protein" [UniProtKB:Q6PIT4] xref: EMBL:AAH29468.1 xref: UniProtKB:Q6PIT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020830 ! ZNF573_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056915 name: FOXR1_HUMAN def: "Forkhead box protein R1" [UniProtKB:Q6PIV2] synonym: "Forkhead box protein N5" EXACT [UniProtKB:Q6PIV2] xref: EMBL:AAH28191.2 xref: EMBL:AAH38969.2 xref: EMBL:BAC76046.1 xref: UniProtKB:Q6PIV2 xref: UniProtKB:Q86UT9 xref: UniProtKB:Q8IXX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017827 ! FOXR1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056916 name: TRAT1_HUMAN def: "T-cell receptor-associated transmembrane adapter 1" [UniProtKB:Q6PIZ9] synonym: "pp29/30" EXACT [UniProtKB:Q6PIZ9] synonym: "T-cell receptor-interacting molecule" EXACT [UniProtKB:Q6PIZ9] synonym: "TRIM" EXACT [UniProtKB:Q6PIZ9] xref: EMBL:AAF29034.1 xref: EMBL:AAH25713.1 xref: UniProtKB:Q6PIZ9 xref: UniProtKB:Q9NZX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020346 ! TRAT1_human relationship: has_function CCO:F0001378 ! transmembrane receptor protein tyrosine kinase adaptor protein activity relationship: has_function CCO:F0006278 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: participates_in CCO:P0000492 ! negative regulation of receptor recycling relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling relationship: participates_in CCO:P0002980 ! positive regulation of T cell receptor signaling pathway relationship: transforms_into CCO:B0071530 ! TRAT1_HUMAN-Phosphotyrosine79 [Term] id: CCO:B0056917 name: Q6PJ34_HUMAN def: "ARHGAP4 protein" [UniProtKB:Q6PJ34] xref: EMBL:AAH23626.1 xref: UniProtKB:Q6PJ34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019715 ! ARHGAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056918 name: Q6PJ92_HUMAN def: "ZNF169 protein" [UniProtKB:Q6PJ92] synonym: "Zinc finger protein 169, isoform CRA_d" EXACT [UniProtKB:Q6PJ92] xref: EMBL:AAH19228.1 xref: EMBL:EAW62881.1 xref: UniProtKB:Q6PJ92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020638 ! ZNF169_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056919 name: Q6PJD0_HUMAN xref: UniProtKB:Q6PJD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056920 name: CN043_HUMAN def: "Uncharacterized protein C14orf43" [UniProtKB:Q6PJG2] xref: EMBL:AAH06511.1 xref: EMBL:AAH09202.1 xref: EMBL:AAH15668.1 xref: EMBL:BAC87133.1 xref: UniProtKB:Q6PJG2 xref: UniProtKB:Q6PK13 xref: UniProtKB:Q6PK59 xref: UniProtKB:Q6ZS23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017397 ! C14orf43_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064403 ! CN043_HUMAN-Phosphoserine461 relationship: transforms_into CCO:B0064404 ! CN043_HUMAN-Phosphoserine661 relationship: transforms_into CCO:B0064405 ! CN043_HUMAN-Phosphoserine700 relationship: transforms_into CCO:B0064406 ! CN043_HUMAN-Phosphothreonine704 relationship: transforms_into CCO:B0064407 ! CN043_HUMAN-Phosphothreonine715 relationship: transforms_into CCO:B0064408 ! CN043_HUMAN-Phosphoserine923 [Term] id: CCO:B0056921 name: Q6PJP1_HUMAN def: "Zinc finger protein 74" [UniProtKB:Q6PJP1] xref: EMBL:AAH13395.1 xref: UniProtKB:Q6PJP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020984 ! ZNF74_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056922 name: FOXR2_HUMAN def: "Forkhead box protein R2" [UniProtKB:Q6PJQ5] synonym: "Forkhead box protein N6" EXACT [UniProtKB:Q6PJQ5] xref: EMBL:AAH12934.1 xref: UniProtKB:Q6PJQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017828 ! FOXR2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056923 name: Q6PK25_HUMAN def: "LOC441453 protein" [UniProtKB:Q6PK25] xref: EMBL:AAH08657.1 xref: UniProtKB:Q6PK25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021194 ! LOC441453_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056924 name: ZNT9_HUMAN def: "Zinc transporter 9" [UniProtKB:Q6PML9] synonym: "HUEL" EXACT [UniProtKB:Q6PML9] synonym: "Human embryonic lung protein" EXACT [UniProtKB:Q6PML9] synonym: "Solute carrier family 30 member 9" EXACT [UniProtKB:Q6PML9] synonym: "ZnT-9" EXACT [UniProtKB:Q6PML9] xref: EMBL:AAB87763.2 xref: EMBL:AAH07732.1 xref: EMBL:AAH16949.1 xref: EMBL:AAH22981.1 xref: EMBL:AAP83846.1 xref: EMBL:AAT02479.1 xref: EMBL:AAY40966.1 xref: UniProtKB:Q4W5B6 xref: UniProtKB:Q6PML9 xref: UniProtKB:Q7Z5I7 xref: UniProtKB:Q8TBB2 xref: UniProtKB:Q9Y6R2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020998 ! SLC30A9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001835 ! cation transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056925 name: Q6PMT2_HUMAN def: "cAMP-specific phosphodiesterase" [UniProtKB:Q6PMT2] xref: EMBL:AAT00628.1 xref: UniProtKB:Q6PMT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019338 ! PDE4A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056926 name: TRAF7_HUMAN def: "E3 ubiquitin-protein ligase TRAF7" [UniProtKB:Q6Q0C0] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q6Q0C0] synonym: "RING finger and WD repeat-containing protein 1" EXACT [UniProtKB:Q6Q0C0] synonym: "RING finger protein 119" EXACT [UniProtKB:Q6Q0C0] synonym: "TNF receptor-associated factor 7" EXACT [UniProtKB:Q6Q0C0] xref: EMBL:AAH24267.1 xref: EMBL:AAS68363.1 xref: EMBL:CAB66855.1 xref: UniProtKB:Q6Q0C0 xref: UniProtKB:Q9H073 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020343 ! TRAF7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019232 ! traf7-map3k3-1 physical interaction relationship: participates_in CCO:P0000409 ! activation of MAPKKK activity relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: transforms_into CCO:B0071527 ! TRAF7_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0071528 ! TRAF7_HUMAN-Phosphoserine91 [Term] id: CCO:B0056927 name: APOA5_HUMAN def: "Apolipoprotein A-V precursor" [UniProtKB:Q6Q788] synonym: "Apo-AV" EXACT [UniProtKB:Q6Q788] synonym: "ApoA-V" EXACT [UniProtKB:Q6Q788] synonym: "Apolipoprotein A5" EXACT [UniProtKB:Q6Q788] synonym: "Regeneration-associated protein 3" EXACT [UniProtKB:Q6Q788] xref: EMBL:AAF25661.1 xref: EMBL:AAF25662.1 xref: EMBL:AAI01788.1 xref: EMBL:AAI01790.1 xref: EMBL:AAQ89109.1 xref: EMBL:AAQ91808.1 xref: EMBL:AAS68229.1 xref: UniProtKB:Q3MIK6 xref: UniProtKB:Q6Q788 xref: UniProtKB:Q6UWK9 xref: UniProtKB:Q9UBJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016993 ! APOA5_human relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003586 ! triglyceride binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004640 ! phosphatidylcholine binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_function CCO:F0008245 ! lipase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0001672 ! chylomicron relationship: located_in CCO:C0002141 ! very-low-density lipoprotein particle relationship: located_in CCO:C0002142 ! low-density lipoprotein particle relationship: located_in CCO:C0002144 ! high-density lipoprotein particle relationship: participates_in CCO:P0002520 ! positive regulation of fatty acid biosynthetic process [Term] id: CCO:B0056928 name: Q6QEF7_HUMAN def: "Breast cancer anti-estrogen resistance 1" [UniProtKB:Q6QEF7] xref: EMBL:AAS48631.1 xref: UniProtKB:Q6QEF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004146 ! BCAR1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004212 ! protein phosphatase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000477 ! focal adhesion relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: participates_in CCO:P0001258 ! positive regulation of cell migration relationship: participates_in CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway relationship: participates_in CCO:P0002757 ! nerve growth factor receptor signaling pathway relationship: participates_in CCO:P0002969 ! antigen receptor-mediated signaling pathway relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway [Term] id: CCO:B0056929 name: FIGLA_HUMAN def: "Factor in the germline alpha" [UniProtKB:Q6QHK4] synonym: "FIGalpha" EXACT [UniProtKB:Q6QHK4] synonym: "Transcription factor FIGa" EXACT [UniProtKB:Q6QHK4] xref: EMBL:AAS48452.1 xref: UniProtKB:Q6QHK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017808 ! FIGLA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056930 name: Q6QJE5_HUMAN def: "Breakpoint cluster region protein" [UniProtKB:Q6QJE5] xref: EMBL:AAS46910.1 xref: UniProtKB:Q6QJE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004156 ! BCR_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056931 name: Q6QJE6_HUMAN def: "Breakpoint cluster region protein" [UniProtKB:Q6QJE6] xref: EMBL:AAS46909.1 xref: UniProtKB:Q6QJE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004156 ! BCR_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056932 name: Q6QJE8_HUMAN def: "Breakpoint cluster region protein" [UniProtKB:Q6QJE8] xref: EMBL:AAS46907.1 xref: UniProtKB:Q6QJE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004156 ! BCR_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056933 name: Q6QME9_HUMAN def: "BCR" [UniProtKB:Q6QME9] xref: EMBL:AAS57923.1 xref: UniProtKB:Q6QME9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056934 name: GP133_HUMAN def: "Probable G-protein coupled receptor 133 precursor" [UniProtKB:Q6QNK2] synonym: "G-protein coupled receptor PGR25" EXACT [UniProtKB:Q6QNK2] xref: EMBL:AAI12308.1 xref: EMBL:AAI12310.1 xref: EMBL:AAO85099.1 xref: EMBL:AAP35063.1 xref: EMBL:AAS37682.1 xref: EMBL:BAD18674.1 xref: UniProtKB:Q2M1L3 xref: UniProtKB:Q6QNK2 xref: UniProtKB:Q6ZMQ1 xref: UniProtKB:Q7Z7M2 xref: UniProtKB:Q86SM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017966 ! GPR133_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0004464 ! cAMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056935 name: Q6RFH8_HUMAN def: "Double homeobox 4c" [UniProtKB:Q6RFH8] xref: EMBL:AAS15569.1 xref: UniProtKB:Q6RFH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021195 ! DUX4c_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056936 name: Q6RKA3_HUMAN def: "Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hip variant" [UniProtKB:Q6RKA3] xref: EMBL:AAR87870.1 xref: UniProtKB:Q6RKA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019286 ! ADCYAP1R1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056937 name: Q6RYQ6_HUMAN def: "FP prostanoid receptor" [UniProtKB:Q6RYQ6] synonym: "Prostaglandin F receptor (FP)" EXACT [UniProtKB:Q6RYQ6] synonym: "Prostaglandin F receptor (FP), isoform CRA_b" EXACT [UniProtKB:Q6RYQ6] xref: EMBL:AAR84381.1 xref: EMBL:CAI23426.1 xref: EMBL:EAX06351.1 xref: UniProtKB:Q6RYQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019373 ! PTGFR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001300 ! prostaglandin F receptor activity relationship: has_function CCO:F0001301 ! thromboxane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056938 name: SHC4_HUMAN def: "SHC-transforming protein 4" [UniProtKB:Q6S5L8] synonym: "hShcD" EXACT [UniProtKB:Q6S5L8] synonym: "Rai-like protein" EXACT [UniProtKB:Q6S5L8] synonym: "RaLP" EXACT [UniProtKB:Q6S5L8] synonym: "SH2 domain protein C4" EXACT [UniProtKB:Q6S5L8] synonym: "Src homology 2 domain-containing-transforming protein C4" EXACT [UniProtKB:Q6S5L8] xref: EMBL:AAH33907.1 xref: EMBL:AAQ88617.1 xref: EMBL:AAR19363.1 xref: UniProtKB:Q6S5L8 xref: UniProtKB:Q6UXQ3 xref: UniProtKB:Q8IYW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019895 ! SHC4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0070501 ! SHC4_HUMAN-Phosphotyrosine424 [Term] id: CCO:B0056939 name: Q6S992_HUMAN def: "Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop splice variant" [UniProtKB:Q6S992] xref: EMBL:AAR26314.1 xref: UniProtKB:Q6S992 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019286 ! ADCYAP1R1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056940 name: TSSK4_HUMAN def: "Testis-specific serine/threonine-protein kinase 4" [UniProtKB:Q6SA08] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q6SA08] synonym: "Serine/threonine-protein kinase 22E" EXACT [UniProtKB:Q6SA08] synonym: "Testis-specific kinase 4" EXACT [UniProtKB:Q6SA08] synonym: "TSK-4" EXACT [UniProtKB:Q6SA08] synonym: "TSSK-4" EXACT [UniProtKB:Q6SA08] xref: EMBL:AAI11089.1 xref: EMBL:AAS17971.1 xref: EMBL:BAC85482.1 xref: UniProtKB:Q2TA60 xref: UniProtKB:Q6SA08 xref: UniProtKB:Q6ZNM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020378 ! TSSK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018762 ! tssk4-creb1-2 physical interaction relationship: participates_in CCO:I0019212 ! tssk4-creb1-1 physical interaction relationship: participates_in CCO:I0019213 ! tssk4-creb1-3 physical interaction relationship: participates_in CCO:I0019214 ! tssk4-creb1-4 phosphorylation relationship: participates_in CCO:P0001651 ! positive regulation of CREB transcription factor activity relationship: transforms_into CCO:B0071610 ! TSSK4_HUMAN-Phosphothreonine197 relationship: transforms_into CCO:B0071611 ! TSSK4_HUMAN-Phosphothreonine251 relationship: transforms_into CCO:B0071612 ! TSSK4_HUMAN-Phosphothreonine256 relationship: transforms_into CCO:B0071613 ! TSSK4_HUMAN-Phosphoserine264 [Term] id: CCO:B0056941 name: SMRD3_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3" [UniProtKB:Q6STE5] synonym: "60 kDa BRG-1/Brm-associated factor subunit C" EXACT [UniProtKB:Q6STE5] synonym: "BRG1-associated factor 60C" EXACT [UniProtKB:Q6STE5] xref: EMBL:AAC50697.1 xref: EMBL:AAH02628.1 xref: EMBL:AAR88510.1 xref: EMBL:AAR88511.1 xref: EMBL:AAS00380.1 xref: EMBL:AAS02031.1 xref: UniProtKB:Q6STE5 xref: UniProtKB:Q75MJ2 xref: UniProtKB:Q75MR8 xref: UniProtKB:Q92926 xref: UniProtKB:Q9BUH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019954 ! SMARCD3_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005585 ! nuclear hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0070674 ! SMRD3_HUMAN-Phosphoserine178 [Term] id: CCO:B0056942 name: SARM1_HUMAN def: "Sterile alpha and TIR motif-containing protein 1" [UniProtKB:Q6SZW1] synonym: "Sterile alpha and Armadillo repeat protein" EXACT [UniProtKB:Q6SZW1] synonym: "Tir-1 homolog" EXACT [UniProtKB:Q6SZW1] xref: EMBL:AAR17520.1 xref: EMBL:BAA25450.1 xref: EMBL:CAB90355.1 xref: UniProtKB:O60277 xref: UniProtKB:Q6SZW1 xref: UniProtKB:Q7LGG3 xref: UniProtKB:Q9NXY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019839 ! SARM1_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056943 name: Q6T1H8_HUMAN def: "Doublesex and mab-3 related transcription factor 1 c" [UniProtKB:Q6T1H8] xref: EMBL:AAR89620.1 xref: UniProtKB:Q6T1H8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017587 ! DMRT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056944 name: RSLBA_HUMAN def: "Ras-like protein family member 11A" [UniProtKB:Q6T310] xref: EMBL:AAI32704.1 xref: EMBL:AAS07577.1 xref: EMBL:CAH73746.1 xref: EMBL:EAX08402.1 xref: UniProtKB:Q6T310 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019801 ! RASL11A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056945 name: ARL9_HUMAN def: "ADP-ribosylation factor-like protein 9" [UniProtKB:Q6T311] xref: EMBL:AAS07576.1 xref: UniProtKB:Q6T311 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017042 ! ARL9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0056946 name: OPN5_HUMAN def: "Opsin-5" [UniProtKB:Q6U736] synonym: "G-protein coupled receptor 136" EXACT [UniProtKB:Q6U736] synonym: "G-protein coupled receptor PGR12" EXACT [UniProtKB:Q6U736] synonym: "Neuropsin" EXACT [UniProtKB:Q6U736] synonym: "Transmembrane protein 13" EXACT [UniProtKB:Q6U736] xref: EMBL:AAI26195.1 xref: EMBL:AAI26199.1 xref: EMBL:AAO85127.1 xref: EMBL:AAP72128.1 xref: EMBL:AAR21109.1 xref: EMBL:CAI20454.1 xref: UniProtKB:A0AV33 xref: UniProtKB:Q5T5B9 xref: UniProtKB:Q5T886 xref: UniProtKB:Q6U736 xref: UniProtKB:Q7Z603 xref: UniProtKB:Q86SL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019050 ! OPN5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056947 name: Z322A_HUMAN def: "Zinc finger protein 322A" [UniProtKB:Q6U7Q0] synonym: "Zinc finger protein 388" EXACT [UniProtKB:Q6U7Q0] synonym: "Zinc finger protein 489" EXACT [UniProtKB:Q6U7Q0] xref: EMBL:AAH50425.2 xref: EMBL:AAH74772.1 xref: EMBL:AAI19670.1 xref: EMBL:AAQ85127.1 xref: EMBL:BAB15637.1 xref: UniProtKB:Q0VDH6 xref: UniProtKB:Q6B0G2 xref: UniProtKB:Q6U7Q0 xref: UniProtKB:Q86W72 xref: UniProtKB:Q9H5I9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020519 ! ZNF322A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056948 name: CRTC3_HUMAN def: "CREB-regulated transcription coactivator 3" [UniProtKB:Q6UUV7] synonym: "TORC-3" EXACT [UniProtKB:Q6UUV7] synonym: "Transducer of CREB protein 3" EXACT [UniProtKB:Q6UUV7] synonym: "Transducer of regulated cAMP response element-binding protein 3" EXACT [UniProtKB:Q6UUV7] xref: EMBL:AAH74730.2 xref: EMBL:AAH74731.3 xref: EMBL:AAQ98858.1 xref: EMBL:BAB15160.1 xref: EMBL:BAC03424.1 xref: UniProtKB:Q6DK61 xref: UniProtKB:Q6DK62 xref: UniProtKB:Q6UUV7 xref: UniProtKB:Q8NF38 xref: UniProtKB:Q9H6U2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017464 ! CRTC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064507 ! CRTC3_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0064508 ! CRTC3_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0064509 ! CRTC3_HUMAN-Phosphothreonine160 relationship: transforms_into CCO:B0064510 ! CRTC3_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0064511 ! CRTC3_HUMAN-Phosphothreonine168 relationship: transforms_into CCO:B0064512 ! CRTC3_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0064513 ! CRTC3_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0064514 ! CRTC3_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0064515 ! CRTC3_HUMAN-Phosphoserine396 relationship: transforms_into CCO:B0064516 ! CRTC3_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0064517 ! CRTC3_HUMAN-Phosphoserine443 relationship: transforms_into CCO:B0064518 ! CRTC3_HUMAN-Phosphoserine543 [Term] id: CCO:B0056949 name: CRTC1_HUMAN def: "CREB-regulated transcription coactivator 1" [UniProtKB:Q6UUV9] synonym: "Mucoepidermoid carcinoma translocated protein 1" EXACT [UniProtKB:Q6UUV9] synonym: "TORC-1" EXACT [UniProtKB:Q6UUV9] synonym: "Transducer of CREB protein 1" EXACT [UniProtKB:Q6UUV9] synonym: "Transducer of regulated cAMP response element-binding protein 1" EXACT [UniProtKB:Q6UUV9] xref: EMBL:AAC97072.1 xref: EMBL:AAH17075.2 xref: EMBL:AAH23614.2 xref: EMBL:AAH28050.1 xref: EMBL:AAK93832.1 xref: EMBL:AAK93833.1 xref: EMBL:AAP12462.1 xref: EMBL:AAP12463.1 xref: EMBL:AAQ98856.1 xref: EMBL:BAA31591.1 xref: EMBL:BAB14822.1 xref: EMBL:EAW84730.1 xref: UniProtKB:A6NMG5 xref: UniProtKB:O75114 xref: UniProtKB:Q6UUV9 xref: UniProtKB:Q6Y3A3 xref: UniProtKB:Q7LDZ2 xref: UniProtKB:Q8IUL3 xref: UniProtKB:Q8IZ34 xref: UniProtKB:Q8IZL1 xref: UniProtKB:Q8N6W3 xref: UniProtKB:Q96AI8 xref: UniProtKB:Q9H801 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017462 ! CRTC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0064479 ! CRTC1_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0064480 ! CRTC1_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0064481 ! CRTC1_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0064482 ! CRTC1_HUMAN-Phosphothreonine149 relationship: transforms_into CCO:B0064483 ! CRTC1_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0064484 ! CRTC1_HUMAN-Phosphothreonine161 relationship: transforms_into CCO:B0064485 ! CRTC1_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0064486 ! CRTC1_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0064487 ! CRTC1_HUMAN-Phosphoserine440 [Term] id: CCO:B0056950 name: CSPG4_HUMAN def: "Chondroitin sulfate proteoglycan 4 precursor" [UniProtKB:Q6UVK1] synonym: "Chondroitin sulfate proteoglycan NG2" EXACT [UniProtKB:Q6UVK1] synonym: "Melanoma chondroitin sulfate proteoglycan" EXACT [UniProtKB:Q6UVK1] synonym: "Melanoma-associated chondroitin sulfate proteoglycan" EXACT [UniProtKB:Q6UVK1] xref: EMBL:AAQ62842.1 xref: EMBL:CAA65529.1 xref: UniProtKB:Q6UVK1 xref: UniProtKB:Q92675 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017481 ! CSPG4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064565 ! CSPG4_HUMAN-Phosphothreonine21 relationship: transforms_into CCO:B0064566 ! CSPG4_HUMAN-Phosphothreonine2252 [Term] id: CCO:B0056951 name: MOXD1_HUMAN def: "DBH-like monooxygenase protein 1 precursor" [UniProtKB:Q6UVY6] synonym: "EC 1.14.17.-" EXACT [UniProtKB:Q6UVY6] synonym: "Monooxygenase X" EXACT [UniProtKB:Q6UVY6] xref: EMBL:AAG09636.1 xref: EMBL:AAH18756.1 xref: EMBL:AAQ89452.1 xref: EMBL:BAC11263.1 xref: EMBL:CAB45692.1 xref: EMBL:CAI15715.1 xref: EMBL:CAI15718.1 xref: EMBL:CAI19937.1 xref: EMBL:CAI19938.1 xref: EMBL:EAW48033.1 xref: EMBL:EAW48034.1 xref: UniProtKB:Q5THU6 xref: UniProtKB:Q6UVY6 xref: UniProtKB:Q8NC97 xref: UniProtKB:Q8WV49 xref: UniProtKB:Q9H4M6 xref: UniProtKB:Q9Y4U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018646 ! MOXD1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0000897 ! dopamine beta-monooxygenase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000887 ! cellular process [Term] id: CCO:B0056952 name: I27RA_HUMAN def: "Interleukin-27 receptor subunit alpha precursor" [UniProtKB:Q6UWB1] synonym: "IL-27R-alpha" EXACT [UniProtKB:Q6UWB1] synonym: "Protein CRL1" EXACT [UniProtKB:Q6UWB1] synonym: "TCCR" EXACT [UniProtKB:Q6UWB1] synonym: "Type I T-cell cytokine receptor" EXACT [UniProtKB:Q6UWB1] synonym: "WSX-1" EXACT [UniProtKB:Q6UWB1] xref: EMBL:AAC39755.1 xref: EMBL:AAG26090.1 xref: EMBL:AAG27297.1 xref: EMBL:AAH28003.1 xref: EMBL:AAQ89235.1 xref: UniProtKB:O60624 xref: UniProtKB:Q6UWB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018201 ! IL27RA_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006140 ! interleukin-27 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002813 ! regulation of isotype switching to IgG isotypes [Term] id: CCO:B0056953 name: ENPP7_HUMAN def: "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 precursor" [UniProtKB:Q6UWV6] synonym: "Alk-SMase" EXACT [UniProtKB:Q6UWV6] synonym: "Alkaline sphingomyelin phosphodiesterase" EXACT [UniProtKB:Q6UWV6] synonym: "E-NPP7" EXACT [UniProtKB:Q6UWV6] synonym: "EC 3.1.4.12" EXACT [UniProtKB:Q6UWV6] synonym: "Intestinal alkaline sphingomyelinase" EXACT [UniProtKB:Q6UWV6] synonym: "NPP-7" EXACT [UniProtKB:Q6UWV6] xref: EMBL:AAH41453.2 xref: EMBL:AAP69661.1 xref: EMBL:AAQ88985.1 xref: EMBL:BAC86504.1 xref: UniProtKB:Q6UWV6 xref: UniProtKB:Q6ZTS5 xref: UniProtKB:Q8IUS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017716 ! ENPP7_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001127 ! sphingomyelin phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000813 ! negative regulation of DNA replication relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0056954 name: Q6UXT6_HUMAN def: "VNFT9373" [UniProtKB:Q6UXT6] xref: EMBL:AAQ88582.1 xref: UniProtKB:Q6UXT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021196 ! UNQ9373_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056955 name: GFRAL_HUMAN def: "GDNF family receptor alpha-like precursor" [UniProtKB:Q6UXV0] xref: EMBL:AAQ88565.1 xref: EMBL:CAH72998.2 xref: UniProtKB:Q5VTF6 xref: UniProtKB:Q6UXV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017919 ! GFRAL_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0001379 ! stress-activated protein kinase signaling pathway [Term] id: CCO:B0056956 name: BI2L2_HUMAN def: "Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2" [UniProtKB:Q6UXY1] synonym: "BAI1-associated protein 2-like protein 2" EXACT [UniProtKB:Q6UXY1] xref: EMBL:AAH15619.1 xref: EMBL:AAQ88531.1 xref: EMBL:CAI17932.1 xref: EMBL:CAI18966.1 xref: UniProtKB:Q6UXY1 xref: UniProtKB:Q96BG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017153 ! BAIAP2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056957 name: UNC5D_HUMAN def: "Netrin receptor UNC5D precursor" [UniProtKB:Q6UXZ4] synonym: "Protein unc-5 homolog D" EXACT [UniProtKB:Q6UXZ4] synonym: "Unc-5 homolog 4" EXACT [UniProtKB:Q6UXZ4] xref: EMBL:AAQ88514.1 xref: EMBL:BAB83663.1 xref: UniProtKB:Q6UXZ4 xref: UniProtKB:Q8WYP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020415 ! UNC5D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071735 ! UNC5D_HUMAN-Phosphothreonine210 [Term] id: CCO:B0056958 name: Q6V963_HUMAN def: "CREB" [UniProtKB:Q6V963] xref: EMBL:AAQ24858.1 xref: UniProtKB:Q6V963 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056959 name: ZN562_HUMAN def: "Zinc finger protein 562" [UniProtKB:Q6V9R5] xref: EMBL:AAQ54330.1 xref: EMBL:BAA90935.1 xref: UniProtKB:Q6V9R5 xref: UniProtKB:Q9NXS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020821 ! ZNF562_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056960 name: KSR2_HUMAN def: "Kinase suppressor of Ras 2" [UniProtKB:Q6VAB6] synonym: "hKSR2" EXACT [UniProtKB:Q6VAB6] xref: EMBL:AAI07107.1 xref: EMBL:AAI07108.1 xref: EMBL:AAI27604.1 xref: EMBL:AAQ24226.1 xref: EMBL:BAC05426.1 xref: UniProtKB:A0PJT2 xref: UniProtKB:Q3B828 xref: UniProtKB:Q6VAB6 xref: UniProtKB:Q8N775 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018448 ! KSR2_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0067500 ! KSR2_HUMAN-Phosphoserine474 [Term] id: CCO:B0056961 name: Q6VMB5_HUMAN def: "DNA polymerase theta" [UniProtKB:Q6VMB5] xref: EMBL:AAR08421.2 xref: UniProtKB:Q6VMB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021197 ! POLQ_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0056962 name: MCAF1_HUMAN def: "Activating transcription factor 7-interacting protein 1" [UniProtKB:Q6VMQ6] synonym: "ATF-interacting protein" EXACT [UniProtKB:Q6VMQ6] synonym: "ATF-IP" EXACT [UniProtKB:Q6VMQ6] synonym: "ATFa-associated modulator" EXACT [UniProtKB:Q6VMQ6] synonym: "hAM" EXACT [UniProtKB:Q6VMQ6] synonym: "MBD1-containing chromatin-associated factor 1" EXACT [UniProtKB:Q6VMQ6] synonym: "P621" EXACT [UniProtKB:Q6VMQ6] xref: EMBL:AAH37312.1 xref: EMBL:AAH63855.1 xref: EMBL:AAO91864.1 xref: EMBL:AAQ92978.1 xref: EMBL:BAA91461.1 xref: EMBL:BAA91751.1 xref: EMBL:CAB45135.1 xref: UniProtKB:Q4G0T9 xref: UniProtKB:Q6P3T3 xref: UniProtKB:Q6VMQ6 xref: UniProtKB:Q86XW5 xref: UniProtKB:Q9NVJ9 xref: UniProtKB:Q9NWC2 xref: UniProtKB:Q9Y4X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018582 ! ATF7IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000646 ! DNA methylation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002599 ! regulation of transcriptional preinitiation complex assembly relationship: transforms_into CCO:B0068045 ! MCAF1_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0068046 ! MCAF1_HUMAN-Phosphothreonine118 relationship: transforms_into CCO:B0068047 ! MCAF1_HUMAN-Phosphoserine473 relationship: transforms_into CCO:B0068048 ! MCAF1_HUMAN-Phosphoserine477 relationship: transforms_into CCO:B0068049 ! MCAF1_HUMAN-Phosphoserine496 relationship: transforms_into CCO:B0068050 ! MCAF1_HUMAN-Phosphoserine673 relationship: transforms_into CCO:B0068051 ! MCAF1_HUMAN-Phosphoserine899 [Term] id: CCO:B0056963 name: Q6VU67_HUMAN def: "Laminin alpha 3 splice variant b2" [UniProtKB:Q6VU67] xref: EMBL:AAQ72571.1 xref: UniProtKB:Q6VU67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021057 ! LAMA3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0056964 name: Q6VU68_HUMAN xref: UniProtKB:Q6VU68 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001407 ! receptor binding relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: located_in CCO:C0001109 ! extracellular matrix relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0056965 name: Q6VU69_HUMAN def: "Laminin alpha 3 splice variant a" [UniProtKB:Q6VU69] xref: EMBL:AAQ72569.1 xref: UniProtKB:Q6VU69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021057 ! LAMA3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000229 ! laminin-1 complex relationship: participates_in CCO:P0001245 ! regulation of cell adhesion relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0056966 name: BCOR_HUMAN def: "BCL-6 corepressor" [UniProtKB:Q6W2J9] synonym: "BCoR" EXACT [UniProtKB:Q6W2J9] xref: EMBL:AAG41429.1 xref: EMBL:AAG41430.1 xref: EMBL:AAH09675.2 xref: EMBL:AAH63536.1 xref: EMBL:AAR08265.1 xref: EMBL:BAA91061.1 xref: EMBL:BAB13401.2 xref: EMBL:BAB85037.1 xref: UniProtKB:Q6P4B6 xref: UniProtKB:Q6W2J9 xref: UniProtKB:Q7Z2K7 xref: UniProtKB:Q8TEB4 xref: UniProtKB:Q96DB3 xref: UniProtKB:Q9H232 xref: UniProtKB:Q9H233 xref: UniProtKB:Q9HCJ7 xref: UniProtKB:Q9NXF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017142 ! BCOR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019179 ! usp7-bcor physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063866 ! BCOR_HUMAN-Phosphoserine423 relationship: transforms_into CCO:B0063867 ! BCOR_HUMAN-Phosphoserine469 relationship: transforms_into CCO:B0063868 ! BCOR_HUMAN-Phosphoserine473 relationship: transforms_into CCO:B0063869 ! BCOR_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0063870 ! BCOR_HUMAN-Phosphoserine1142 relationship: transforms_into CCO:B0063871 ! BCOR_HUMAN-Phosphoserine1410 [Term] id: CCO:B0056967 name: Q6W3F3_HUMAN def: "SMAC3" [UniProtKB:Q6W3F3] xref: EMBL:AAQ86939.1 xref: UniProtKB:Q6W3F3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation [Term] id: CCO:B0056968 name: NPSR1_HUMAN def: "Neuropeptide S receptor" [UniProtKB:Q6W5P4] synonym: "G-protein coupled receptor 154" EXACT [UniProtKB:Q6W5P4] synonym: "G-protein coupled receptor for asthma susceptibility" EXACT [UniProtKB:Q6W5P4] synonym: "G-protein coupled receptor PGR14" EXACT [UniProtKB:Q6W5P4] xref: EMBL:AAQ76966.1 xref: EMBL:AAQ76967.1 xref: EMBL:AAQ76968.1 xref: EMBL:AAQ76969.1 xref: EMBL:AAQ76970.1 xref: EMBL:AAQ76971.1 xref: EMBL:AAQ76972.1 xref: EMBL:AAX63744.1 xref: EMBL:AAX63745.1 xref: EMBL:AAX63746.1 xref: EMBL:ABB72550.1 xref: EMBL:BAD18811.1 xref: UniProtKB:Q2XP58 xref: UniProtKB:Q56H76 xref: UniProtKB:Q56H77 xref: UniProtKB:Q56H78 xref: UniProtKB:Q6JSL4 xref: UniProtKB:Q6JSL5 xref: UniProtKB:Q6JSL6 xref: UniProtKB:Q6JSL7 xref: UniProtKB:Q6JSL8 xref: UniProtKB:Q6W5P3 xref: UniProtKB:Q6W5P4 xref: UniProtKB:Q6ZMB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018838 ! NPSR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001338 ! vasopressin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056969 name: Q6WMU8_HUMAN def: "Zinc finger protein 434" [UniProtKB:Q6WMU8] synonym: "cDNA FLJ77128, highly similar to Homo sapiens zinc finger protein 434 (ZNF434) mRNA" EXACT [UniProtKB:Q6WMU8] xref: EMBL:AAQ62844.1 xref: EMBL:BAF83902.1 xref: UniProtKB:Q6WMU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020748 ! ZNF434_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056970 name: SOSD1_HUMAN def: "Sclerostin domain-containing protein 1 precursor" [UniProtKB:Q6X4U4] synonym: "Ectodermal BMP inhibitor" EXACT [UniProtKB:Q6X4U4] synonym: "Ectodin" EXACT [UniProtKB:Q6X4U4] synonym: "USAG-1" EXACT [UniProtKB:Q6X4U4] synonym: "Uterine sensitization-associated gene 1 protein" EXACT [UniProtKB:Q6X4U4] xref: EMBL:AAH08484.1 xref: EMBL:AAL57219.1 xref: EMBL:AAQ83296.1 xref: EMBL:AAQ96855.1 xref: EMBL:BAC20331.1 xref: EMBL:CAB43243.2 xref: UniProtKB:Q6X4U4 xref: UniProtKB:Q96HJ7 xref: UniProtKB:Q9Y3U3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019987 ! SOSTDC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0056971 name: ASCL4_HUMAN def: "Achaete-scute homolog 4" [UniProtKB:Q6XD76] synonym: "Achaete-scute-like protein 4" EXACT [UniProtKB:Q6XD76] xref: EMBL:AAI28212.1 xref: EMBL:AAI28213.1 xref: EMBL:AAP69222.1 xref: EMBL:DAA01055.1 xref: UniProtKB:Q6XD76 xref: UniProtKB:Q7RTS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017078 ! ASCL4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056972 name: LBX2_HUMAN def: "Transcription factor LBX2" [UniProtKB:Q6XYB7] synonym: "Ladybird homeobox protein homolog 2" EXACT [UniProtKB:Q6XYB7] xref: EMBL:AAI50518.1 xref: EMBL:AAP34476.1 xref: EMBL:AAP74384.1 xref: EMBL:EAW99636.1 xref: UniProtKB:Q6XYB7 xref: UniProtKB:Q7Z5Y8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018461 ! LBX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056973 name: Q6XZE5_HUMAN def: "CINCIN1" [UniProtKB:Q6XZE5] xref: EMBL:AAP40637.1 xref: UniProtKB:Q6XZE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021198 ! CINCIN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0056974 name: DNMBP_HUMAN def: "Dynamin-binding protein" [UniProtKB:Q6XZF7] synonym: "Scaffold protein Tuba" EXACT [UniProtKB:Q6XZF7] xref: EMBL:AAH41628.1 xref: EMBL:AAP34307.1 xref: EMBL:BAA76854.1 xref: UniProtKB:Q6XZF7 xref: UniProtKB:Q8IVY3 xref: UniProtKB:Q9Y2L3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017598 ! DNMBP_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0056975 name: Q6YI47_HUMAN def: "Upstream stimulatory factor 2c" [UniProtKB:Q6YI47] xref: EMBL:AAN63092.1 xref: UniProtKB:Q6YI47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020422 ! USF2_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056976 name: Q6ZMJ1_HUMAN def: "cDNA FLJ23908 fis, clone ADSU00701" [UniProtKB:Q6ZMJ1] xref: EMBL:BAD18734.1 xref: UniProtKB:Q6ZMJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056977 name: Q6ZMJ6_HUMAN def: "FLJ00420 protein" [UniProtKB:Q6ZMJ6] xref: EMBL:BAD18729.1 xref: UniProtKB:Q6ZMJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021199 ! FLJ00420_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0056978 name: Q6ZMK5_HUMAN def: "FLJ00322 protein" [UniProtKB:Q6ZMK5] xref: EMBL:BAD18720.1 xref: UniProtKB:Q6ZMK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021200 ! NPIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056979 name: Q6ZMK6_HUMAN def: "FLJ00320 protein" [UniProtKB:Q6ZMK6] xref: EMBL:BAD18719.1 xref: UniProtKB:Q6ZMK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021201 ! FLJ00320_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056980 name: Q6ZMK7_HUMAN def: "FLJ00312 protein" [UniProtKB:Q6ZMK7] xref: EMBL:BAD18718.1 xref: UniProtKB:Q6ZMK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021202 ! FLJ00312_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0056981 name: Q6ZML0_HUMAN def: "FLJ00301 protein" [UniProtKB:Q6ZML0] xref: EMBL:BAD18715.1 xref: UniProtKB:Q6ZML0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021203 ! FLJ00301_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056982 name: Q6ZMM3_HUMAN def: "cDNA FLJ16823 fis, clone UTERU2017492, highly similar to Calcipressin 1" [UniProtKB:Q6ZMM3] xref: EMBL:BAD18702.1 xref: UniProtKB:Q6ZMM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0056983 name: Q6ZMM6_HUMAN def: "cDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor HMR" [UniProtKB:Q6ZMM6] xref: EMBL:BAD18699.1 xref: UniProtKB:Q6ZMM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056984 name: Q6ZMN0_HUMAN def: "cDNA FLJ16811 fis, clone THYMU3024602, highly similar to Cell surface glycoprotein EMR1" [UniProtKB:Q6ZMN0] xref: EMBL:BAD18695.1 xref: UniProtKB:Q6ZMN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056985 name: Q6ZMN4_HUMAN def: "cDNA FLJ16799 fis, clone TESTI4002988, moderately similar to Zinc finger protein 208" [UniProtKB:Q6ZMN4] xref: EMBL:BAD18691.1 xref: UniProtKB:Q6ZMN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056986 name: Q6ZMP1_HUMAN def: "cDNA FLJ16789 fis, clone PROST2010326, highly similar to Homo sapiens G protein-coupled receptor 56 (GPR56)" [UniProtKB:Q6ZMP1] xref: EMBL:BAD18684.1 xref: UniProtKB:Q6ZMP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0056987 name: Q6ZMP3_HUMAN xref: UniProtKB:Q6ZMP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056988 name: Q6ZMP8_HUMAN def: "cDNA FLJ16774 fis, clone BRCAN2019772, highly similar to Orphan nuclear receptor NR2E1" [UniProtKB:Q6ZMP8] synonym: "Nuclear receptor subfamily 2, group E, member 1" EXACT [UniProtKB:Q6ZMP8] synonym: "Nuclear receptor subfamily 2, group E, member 1, isoform CRA_b" EXACT [UniProtKB:Q6ZMP8] xref: EMBL:BAD18677.1 xref: EMBL:CAO03480.1 xref: EMBL:EAW48386.1 xref: UniProtKB:Q6ZMP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018858 ! NR2E1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056989 name: Q6ZMP9_HUMAN def: "cDNA FLJ16773 fis, clone BRAWH3046240, highly similar to Probable G protein-coupled receptor GPR35" [UniProtKB:Q6ZMP9] xref: EMBL:BAD18676.1 xref: UniProtKB:Q6ZMP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0056990 name: Q6ZMR1_HUMAN def: "cDNA FLJ16750 fis, clone ADRGL2011190, highly similar to cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17)" [UniProtKB:Q6ZMR1] xref: EMBL:BAD18664.1 xref: UniProtKB:Q6ZMR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056991 name: ZN783_HUMAN def: "Protein ZNF783" [UniProtKB:Q6ZMS7] xref: EMBL:BAD18648.1 xref: UniProtKB:Q6ZMS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020937 ! ZNF783_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056992 name: STAC2_HUMAN def: "SH3 and cysteine-rich domain-containing protein 2" [UniProtKB:Q6ZMT1] synonym: "24b2/STAC2" EXACT [UniProtKB:Q6ZMT1] synonym: "SRC homology 3 and cysteine-rich domain protein 2" EXACT [UniProtKB:Q6ZMT1] xref: EMBL:AAI09232.1 xref: EMBL:BAD18644.1 xref: EMBL:CAE75539.1 xref: UniProtKB:Q32MA3 xref: UniProtKB:Q6ZMT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020060 ! STAC2_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019063 ! atxn1-stac2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0056993 name: Q6ZMT6_HUMAN xref: UniProtKB:Q6ZMT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056994 name: YD026_HUMAN def: "Putative death domain-containing protein FLJ16686" [UniProtKB:Q6ZMT9] xref: EMBL:AAI57886.1 xref: EMBL:BAD18636.1 xref: UniProtKB:B2RXK4 xref: UniProtKB:Q6ZMT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0056995 name: Q6ZMU6_HUMAN xref: UniProtKB:Q6ZMU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056996 name: ZN730_HUMAN def: "Putative zinc finger protein 730" [UniProtKB:Q6ZMV8] xref: EMBL:BAD18617.1 xref: UniProtKB:Q6ZMV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022812 ! ZNF730_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056997 name: ZN782_HUMAN def: "Zinc finger protein 782" [UniProtKB:Q6ZMW2] xref: EMBL:BAD18613.1 xref: UniProtKB:Q6ZMW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020936 ! ZNF782_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056998 name: ZN517_HUMAN def: "Zinc finger protein 517" [UniProtKB:Q6ZMY9] xref: EMBL:BAD18586.1 xref: UniProtKB:Q6ZMY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020793 ! ZNF517_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0056999 name: Q6ZMZ2_HUMAN xref: UniProtKB:Q6ZMZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057000 name: MASTR_HUMAN def: "MEF2-activating SAP transcriptional regulatory protein" [UniProtKB:Q6ZN01] xref: EMBL:AAI05057.1 xref: EMBL:AAI05059.1 xref: EMBL:AAI06048.1 xref: EMBL:BAC04152.1 xref: EMBL:BAD18574.1 xref: EMBL:EAW52390.1 xref: EMBL:EAW52392.1 xref: UniProtKB:Q3KQU9 xref: UniProtKB:Q6ZN01 xref: UniProtKB:Q8N9Y3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018572 ! MASTR_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057001 name: ZN813_HUMAN def: "Zinc finger protein 813" [UniProtKB:Q6ZN06] xref: EMBL:BAD18569.1 xref: UniProtKB:Q6ZN06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020950 ! ZNF813_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057002 name: ZNF66_HUMAN def: "Zinc finger protein 66" [UniProtKB:Q6ZN08] xref: EMBL:AAA61333.1 xref: EMBL:BAD18567.1 xref: UniProtKB:Q15939 xref: UniProtKB:Q6ZN08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020979 ! ZNF66_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057003 name: ZN793_HUMAN def: "Zinc finger protein 793" [UniProtKB:Q6ZN11] xref: EMBL:BAD18564.1 xref: EMBL:CAD97772.1 xref: UniProtKB:Q6ZN11 xref: UniProtKB:Q7Z3Q9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020946 ! ZNF793_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057004 name: Q6ZN13_HUMAN def: "cDNA FLJ16525 fis, clone OCBBF2005433, weakly similar to N-CHIMAERIN" [UniProtKB:Q6ZN13] xref: EMBL:BAD18562.1 xref: UniProtKB:Q6ZN13 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057005 name: LN28B_HUMAN def: "Lin-28 homolog B" [UniProtKB:Q6ZN17] xref: EMBL:AAI27713.1 xref: EMBL:AAI27714.1 xref: EMBL:AAI41961.1 xref: EMBL:AAZ38897.1 xref: EMBL:BAD18558.1 xref: EMBL:CAI20969.2 xref: EMBL:CAI21661.2 xref: UniProtKB:A1L165 xref: UniProtKB:Q5TCM4 xref: UniProtKB:Q6ZN17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018514 ! LIN28B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057006 name: AEBP2_HUMAN def: "Zinc finger protein AEBP2" [UniProtKB:Q6ZN18] synonym: "Adipocyte enhancer-binding protein 2" EXACT [UniProtKB:Q6ZN18] synonym: "AE-binding protein 2" EXACT [UniProtKB:Q6ZN18] xref: EMBL:AAH15624.1 xref: EMBL:AAH22220.1 xref: EMBL:BAD18513.1 xref: EMBL:BAD18557.1 xref: EMBL:BAD92621.1 xref: EMBL:EAW96400.1 xref: UniProtKB:Q59FS5 xref: UniProtKB:Q6ZN18 xref: UniProtKB:Q6ZN62 xref: UniProtKB:Q96BG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016927 ! AEBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065452 ! AEBP2_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0065453 ! AEBP2_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0065454 ! AEBP2_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0065455 ! AEBP2_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0065456 ! AEBP2_HUMAN-Phosphoserine210 relationship: transforms_into CCO:B0065457 ! AEBP2_HUMAN-Phosphoserine211 [Term] id: CCO:B0057007 name: ZN841_HUMAN def: "Zinc finger protein 841" [UniProtKB:Q6ZN19] xref: EMBL:BAC04190.1 xref: EMBL:BAC85253.1 xref: EMBL:BAD18493.1 xref: EMBL:BAD18556.1 xref: UniProtKB:Q6ZN19 xref: UniProtKB:Q6ZN82 xref: UniProtKB:Q6ZP71 xref: UniProtKB:Q8N9U7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022821 ! ZNF841_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057008 name: ETV3L_HUMAN def: "ETS translocation variant 3-like protein" [UniProtKB:Q6ZN32] xref: EMBL:BAD18543.1 xref: UniProtKB:Q6ZN32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017738 ! ETV3L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057009 name: Q6ZN34_HUMAN xref: UniProtKB:Q6ZN34 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057010 name: UNC5A_HUMAN def: "Netrin receptor UNC5A precursor" [UniProtKB:Q6ZN44] synonym: "Protein unc-5 homolog A" EXACT [UniProtKB:Q6ZN44] synonym: "Unc-5 homolog 1" EXACT [UniProtKB:Q6ZN44] xref: EMBL:AAH09333.2 xref: EMBL:BAB85562.1 xref: EMBL:BAD18531.1 xref: UniProtKB:Q6ZN44 xref: UniProtKB:Q8TF26 xref: UniProtKB:Q96GP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020412 ! UNC5A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057011 name: DEFI8_HUMAN def: "Differentially expressed in FDCP 8 homolog" [UniProtKB:Q6ZN54] synonym: "DEF-8" EXACT [UniProtKB:Q6ZN54] xref: EMBL:AAH15482.1 xref: EMBL:AAI05593.1 xref: EMBL:BAA91000.1 xref: EMBL:BAC04802.1 xref: EMBL:BAD18521.1 xref: EMBL:EAW66667.1 xref: UniProtKB:Q6ZN54 xref: UniProtKB:Q8N8N3 xref: UniProtKB:Q9NXL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017550 ! DEF8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057012 name: ZN574_HUMAN def: "Zinc finger protein 574" [UniProtKB:Q6ZN55] xref: EMBL:AAH01184.2 xref: EMBL:AAH71962.1 xref: EMBL:BAB15225.1 xref: EMBL:BAC11210.1 xref: EMBL:BAD18520.1 xref: EMBL:BAD18565.1 xref: UniProtKB:Q6IPE0 xref: UniProtKB:Q6ZN10 xref: UniProtKB:Q6ZN55 xref: UniProtKB:Q7L5Z5 xref: UniProtKB:Q8NCE3 xref: UniProtKB:Q9H6N0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020831 ! ZNF574_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072151 ! ZN574_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0072152 ! ZN574_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0072153 ! ZN574_HUMAN-Phosphothreonine154 relationship: transforms_into CCO:B0072154 ! ZN574_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0072155 ! ZN574_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0072156 ! ZN574_HUMAN-Phosphoserine717 relationship: transforms_into CCO:B0072157 ! ZN574_HUMAN-Phosphothreonine724 relationship: transforms_into CCO:B0072158 ! ZN574_HUMAN-Phosphoserine728 [Term] id: CCO:B0057013 name: ZFP2_HUMAN def: "Zinc finger protein 2 homolog" [UniProtKB:Q6ZN57] synonym: "Zfp-2" EXACT [UniProtKB:Q6ZN57] xref: EMBL:AAI32780.1 xref: EMBL:AAI32782.1 xref: EMBL:BAB15104.1 xref: EMBL:BAD18518.1 xref: UniProtKB:Q6ZN57 xref: UniProtKB:Q9H6Z6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020588 ! ZFP2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057014 name: Q6ZN78_HUMAN def: "cDNA FLJ16354 fis, clone TESTI4000319, weakly similar to GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR RALGDS FORM B" [UniProtKB:Q6ZN78] xref: EMBL:BAD18497.1 xref: UniProtKB:Q6ZN78 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057015 name: Z705A_HUMAN def: "Zinc finger protein 705A" [UniProtKB:Q6ZN79] xref: EMBL:BAD18496.1 xref: UniProtKB:Q6ZN79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020534 ! ZNF705A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057016 name: Q6ZN87_HUMAN def: "cDNA FLJ16334 fis, clone TESOP2006865, moderately similar to ZINC FINGER PROTEIN MFG-3" [UniProtKB:Q6ZN87] xref: EMBL:BAD18488.1 xref: UniProtKB:Q6ZN87 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057017 name: ZN836_HUMAN def: "Zinc finger protein 836" [UniProtKB:Q6ZNA1] xref: EMBL:BAD18474.1 xref: UniProtKB:Q6ZNA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022819 ! ZNF836_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057018 name: Q6ZNA9_HUMAN def: "cDNA FLJ16258 fis, clone HSYRA2005628, moderately similar to ZINC FINGER PROTEIN 195" [UniProtKB:Q6ZNA9] xref: EMBL:BAD18466.1 xref: UniProtKB:Q6ZNA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057019 name: NFXL1_HUMAN def: "NF-X1-type zinc finger protein NFXL1" [UniProtKB:Q6ZNB6] synonym: "hOZFP" EXACT [UniProtKB:Q6ZNB6] synonym: "Ovarian zinc finger protein" EXACT [UniProtKB:Q6ZNB6] xref: EMBL:AAH18019.1 xref: EMBL:AAH51193.1 xref: EMBL:AAY40918.1 xref: EMBL:BAD18459.1 xref: UniProtKB:Q6ZNB6 xref: UniProtKB:Q86VG1 xref: UniProtKB:Q8WVH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018782 ! NFXL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068694 ! NFXL1_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0068695 ! NFXL1_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0068696 ! NFXL1_HUMAN-Phosphoserine106 relationship: transforms_into CCO:B0068697 ! NFXL1_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0068698 ! NFXL1_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0068699 ! NFXL1_HUMAN-Phosphoserine109 [Term] id: CCO:B0057020 name: Q6ZNE3_HUMAN xref: UniProtKB:Q6ZNE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057021 name: Q6ZNF7_HUMAN def: "cDNA FLJ16146 fis, clone BRAMY2040159, highly similar to Homo sapiens MRIP-1 mRNA" [UniProtKB:Q6ZNF7] xref: EMBL:BAD18418.1 xref: UniProtKB:Q6ZNF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0057022 name: ZN620_HUMAN def: "Zinc finger protein 620" [UniProtKB:Q6ZNG0] xref: EMBL:BAC04203.1 xref: EMBL:BAD18415.1 xref: UniProtKB:Q6ZNG0 xref: UniProtKB:Q8N223 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020860 ! ZNF620_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057023 name: ZN600_HUMAN def: "Zinc finger protein 600" [UniProtKB:Q6ZNG1] xref: EMBL:BAD18414.1 xref: EMBL:CAE45968.1 xref: UniProtKB:Q6MZR0 xref: UniProtKB:Q6ZNG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020849 ! ZNF600_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072177 ! ZN600_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0072178 ! ZN600_HUMAN-Phosphoserine124 [Term] id: CCO:B0057024 name: DBX2_HUMAN def: "Homeobox protein DBX2" [UniProtKB:Q6ZNG2] synonym: "Developing brain homeobox protein 2" EXACT [UniProtKB:Q6ZNG2] xref: EMBL:BAD18413.1 xref: UniProtKB:Q6ZNG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017528 ! DBX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057025 name: KRBA2_HUMAN def: "KRAB-A domain-containing protein 2" [UniProtKB:Q6ZNG9] xref: EMBL:AAH33390.1 xref: EMBL:BAD18406.1 xref: UniProtKB:Q6ZNG9 xref: UniProtKB:Q8IYY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018436 ! KRBA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067440 ! KRBA2_HUMAN-Phosphoserine115 relationship: transforms_into CCO:B0067441 ! KRBA2_HUMAN-Phosphothreonine117 relationship: transforms_into CCO:B0067442 ! KRBA2_HUMAN-Phosphotyrosine125 relationship: transforms_into CCO:B0067443 ! KRBA2_HUMAN-Phosphoserine483 [Term] id: CCO:B0057026 name: ZN497_HUMAN def: "Zinc finger protein 497" [UniProtKB:Q6ZNH5] xref: EMBL:AAF16412.1 xref: EMBL:AAI25274.1 xref: EMBL:BAC86660.1 xref: EMBL:BAD18400.1 xref: UniProtKB:Q05AG8 xref: UniProtKB:Q6ZNH5 xref: UniProtKB:Q6ZTD2 xref: UniProtKB:Q9UIA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020779 ! ZNF497_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057027 name: Q6ZNK8_HUMAN def: "FLJ00288 protein" [UniProtKB:Q6ZNK8] xref: EMBL:BAC85136.1 xref: UniProtKB:Q6ZNK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021204 ! FLJ00288_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057028 name: YP009_HUMAN def: "GPS, PLAT and transmembrane domain-containing protein FLJ00285" [UniProtKB:Q6ZNL0] xref: EMBL:BAC85134.1 xref: EMBL:BAC85135.1 xref: UniProtKB:Q6ZNK9 xref: UniProtKB:Q6ZNL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057029 name: FGD5_HUMAN def: "FYVE, RhoGEF and PH domain-containing protein 5" [UniProtKB:Q6ZNL6] synonym: "Zinc finger FYVE domain-containing protein 23" EXACT [UniProtKB:Q6ZNL6] xref: EMBL:AAH35364.1 xref: EMBL:BAC04878.1 xref: EMBL:BAC04989.1 xref: EMBL:BAC85128.1 xref: EMBL:CAD98090.1 xref: EMBL:CAE45896.2 xref: UniProtKB:Q6MZY1 xref: UniProtKB:Q6ZNL6 xref: UniProtKB:Q7Z303 xref: UniProtKB:Q8IYP3 xref: UniProtKB:Q8N861 xref: UniProtKB:Q8N8G4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017788 ! FGD5_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004648 ! small GTPase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002156 ! regulation of Cdc42 GTPase activity relationship: transforms_into CCO:B0066180 ! FGD5_HUMAN-Phosphoserine632 relationship: transforms_into CCO:B0066181 ! FGD5_HUMAN-Phosphoserine635 [Term] id: CCO:B0057030 name: Q6ZNU3_HUMAN def: "CDNA FLJ27146 fis, clone SPL09537" [UniProtKB:Q6ZNU3] xref: EMBL:BAC85402.1 xref: UniProtKB:Q6ZNU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057031 name: Q6ZP45_HUMAN def: "CDNA FLJ26517 fis, clone KDN07769" [UniProtKB:Q6ZP45] xref: EMBL:BAC85280.1 xref: UniProtKB:Q6ZP45 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057032 name: YB047_HUMAN def: "Putative uncharacterized protein FLJ46838" [UniProtKB:Q6ZQN3] xref: EMBL:BAC87651.1 xref: UniProtKB:Q6ZQN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057033 name: Q6ZQV2_HUMAN xref: UniProtKB:Q6ZQV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001476 ! CD27 receptor binding relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0057034 name: Q6ZQV4_HUMAN def: "cDNA FLJ46868 fis, clone UTERU3012414, highly similar to Guanine nucleotide-binding protein, alpha-12 subunit" [UniProtKB:Q6ZQV4] xref: EMBL:BAC87579.1 xref: UniProtKB:Q6ZQV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057035 name: ZN788_HUMAN def: "Zinc finger protein 788" [UniProtKB:Q6ZQV5] xref: EMBL:BAC87366.1 xref: EMBL:BAC87578.1 xref: UniProtKB:Q6ZQV5 xref: UniProtKB:Q6ZRE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020941 ! ZNF788_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057036 name: Q6ZQX8_HUMAN xref: UniProtKB:Q6ZQX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057037 name: PKHG7_HUMAN def: "Pleckstrin homology domain-containing family G member 7" [UniProtKB:Q6ZR37] xref: EMBL:BAC87483.1 xref: UniProtKB:Q6ZR37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019419 ! PLEKHG7_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057038 name: ZN493_HUMAN def: "Zinc finger protein 493" [UniProtKB:Q6ZR52] xref: EMBL:BAC04232.1 xref: EMBL:BAC04591.1 xref: EMBL:BAC86997.1 xref: EMBL:BAC87465.1 xref: EMBL:BAD92323.1 xref: UniProtKB:Q59GM3 xref: UniProtKB:Q6ZR52 xref: UniProtKB:Q6ZSF6 xref: UniProtKB:Q8N1Z6 xref: UniProtKB:Q8N965 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020777 ! ZNF493_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057039 name: ZN818_HUMAN def: "Putative zinc finger protein 818" [UniProtKB:Q6ZRF7] xref: EMBL:BAC87353.1 xref: UniProtKB:Q6ZRF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020951 ! ZNF818P_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057040 name: RHGXX_HUMAN def: "Putative Rho GTPase-activating protein FLJ46335 precursor" [UniProtKB:Q6ZRI8] xref: EMBL:AAH63790.1 xref: EMBL:BAB70776.1 xref: EMBL:BAC87322.1 xref: EMBL:CAI41399.1 xref: EMBL:CAI41400.1 xref: EMBL:CAI41401.1 xref: UniProtKB:Q5JRL9 xref: UniProtKB:Q5JRM0 xref: UniProtKB:Q6ZRI8 xref: UniProtKB:Q96NU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057041 name: DCDC5_HUMAN def: "Doublecortin domain-containing protein 5" [UniProtKB:Q6ZRR9] xref: EMBL:BAC87240.1 xref: EMBL:CAO03425.1 xref: UniProtKB:B1AL47 xref: UniProtKB:Q6ZRR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017531 ! DCDC5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057042 name: SRCAP_HUMAN def: "Helicase SRCAP" [UniProtKB:Q6ZRS2] synonym: "Domino homolog 2" EXACT [UniProtKB:Q6ZRS2] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q6ZRS2] synonym: "Snf2-related CBP activator" EXACT [UniProtKB:Q6ZRS2] xref: EMBL:AAD39760.1 xref: EMBL:AAH52963.1 xref: EMBL:BAA20768.2 xref: EMBL:BAC87237.1 xref: UniProtKB:O15026 xref: UniProtKB:Q6ZRS2 xref: UniProtKB:Q7Z744 xref: UniProtKB:Q9Y5L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020034 ! SRCAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070898 ! SRCAP_HUMAN-Phosphoserine248 relationship: transforms_into CCO:B0070899 ! SRCAP_HUMAN-Phosphothreonine2258 relationship: transforms_into CCO:B0070900 ! SRCAP_HUMAN-Phosphothreonine2425 relationship: transforms_into CCO:B0070901 ! SRCAP_HUMAN-Phosphoserine2430 relationship: transforms_into CCO:B0070902 ! SRCAP_HUMAN-Phosphoserine2869 relationship: transforms_into CCO:B0070903 ! SRCAP_HUMAN-Phosphoserine3148 [Term] id: CCO:B0057043 name: Q6ZRZ2_HUMAN xref: UniProtKB:Q6ZRZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0057044 name: Q6ZRZ7_HUMAN def: "cDNA FLJ45950 fis, clone PLACE7008136" [UniProtKB:Q6ZRZ7] xref: EMBL:BAC87159.1 xref: UniProtKB:Q6ZRZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057045 name: ZN662_HUMAN def: "Zinc finger protein 662" [UniProtKB:Q6ZS27] xref: EMBL:BAC87129.1 xref: EMBL:BAC87565.1 xref: EMBL:BAD18417.1 xref: UniProtKB:Q6ZNF8 xref: UniProtKB:Q6ZQW8 xref: UniProtKB:Q6ZS27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020880 ! ZNF662_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057046 name: Q6ZS32_HUMAN def: "cDNA FLJ45870 fis, clone OCBBF3005330, highly similar to FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68)" [UniProtKB:Q6ZS32] xref: EMBL:BAC87123.1 xref: UniProtKB:Q6ZS32 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003117 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057047 name: Q6ZS35_HUMAN xref: UniProtKB:Q6ZS35 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057048 name: Q6ZS47_HUMAN def: "cDNA FLJ45839 fis, clone NTONG2003805, highly similar to Zinc finger protein 45" [UniProtKB:Q6ZS47] xref: EMBL:BAC87108.1 xref: UniProtKB:Q6ZS47 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057049 name: Q6ZS74_HUMAN def: "cDNA FLJ45773 fis, clone NETRP2003448, highly similar to Ras-related protein RAL-B" [UniProtKB:Q6ZS74] synonym: "V-ral simian leukemia viral oncogene homolog B (Ras related; GTP binding protein), isoform CRA_b" EXACT [UniProtKB:Q6ZS74] xref: EMBL:BAC87080.1 xref: EMBL:EAW95242.1 xref: UniProtKB:Q6ZS74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019619 ! RALB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057050 name: R9BP_HUMAN def: "Regulator of G-protein signaling 9-binding protein" [UniProtKB:Q6ZS82] synonym: "RGS9-anchoring protein" EXACT [UniProtKB:Q6ZS82] xref: EMBL:BAC85865.1 xref: EMBL:BAC87072.1 xref: UniProtKB:Q6ZS82 xref: UniProtKB:Q6ZVJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019570 ! RGS9BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0057051 name: Q6ZS96_HUMAN def: "Protein Wnt" [UniProtKB:Q6ZS96] xref: EMBL:AAH64534.1 xref: EMBL:BAC87058.1 xref: UniProtKB:Q6ZS96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020498 ! WNT9B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0057052 name: ZN509_HUMAN def: "Zinc finger protein 509" [UniProtKB:Q6ZSB9] xref: EMBL:AAH16477.1 xref: EMBL:AAH89401.1 xref: EMBL:BAC87035.1 xref: EMBL:BAD92703.1 xref: UniProtKB:Q59FJ4 xref: UniProtKB:Q5EBN0 xref: UniProtKB:Q6ZSB9 xref: UniProtKB:Q8TB80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020787 ! ZNF509_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072139 ! ZN509_HUMAN-Phosphotyrosine652 [Term] id: CCO:B0057053 name: Q6ZSD0_HUMAN def: "cDNA FLJ45630 fis, clone CHONS2001287, moderately similar to INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3" [UniProtKB:Q6ZSD0] xref: EMBL:BAC87023.1 xref: UniProtKB:Q6ZSD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0057054 name: Q6ZSG5_HUMAN xref: UniProtKB:Q6ZSG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057055 name: Q6ZSK3_HUMAN xref: UniProtKB:Q6ZSK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057056 name: Q6ZSN9_HUMAN def: "cDNA FLJ45337 fis, clone BRHIP3007960" [UniProtKB:Q6ZSN9] synonym: "Uncharacterized protein ENSP00000374034" EXACT [UniProtKB:Q6ZSN9] xref: EMBL:BAC86909.1 xref: UniProtKB:A6NJP1 xref: UniProtKB:Q6ZSN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057057 name: Q6ZSP0_HUMAN def: "Protein Wnt" [UniProtKB:Q6ZSP0] xref: EMBL:BAC86908.1 xref: UniProtKB:Q6ZSP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0057058 name: ZN621_HUMAN def: "Zinc finger protein 621" [UniProtKB:Q6ZSS3] xref: EMBL:AAI01620.1 xref: EMBL:AAI13416.1 xref: EMBL:BAB85061.1 xref: EMBL:BAC86873.1 xref: EMBL:CAH18124.1 xref: UniProtKB:Q14DC7 xref: UniProtKB:Q6ZSS3 xref: UniProtKB:Q8TE91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020861 ! ZNF621_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057059 name: Q6ZSX2_HUMAN xref: UniProtKB:Q6ZSX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057060 name: ARHGI_HUMAN def: "Rho guanine nucleotide exchange factor 18" [UniProtKB:Q6ZSZ5] synonym: "114 kDa Rho-specific guanine nucleotide exchange factor" EXACT [UniProtKB:Q6ZSZ5] synonym: "p114-Rho-GEF" EXACT [UniProtKB:Q6ZSZ5] synonym: "p114RhoGEF" EXACT [UniProtKB:Q6ZSZ5] synonym: "SA-RhoGEF" EXACT [UniProtKB:Q6ZSZ5] synonym: "Septin-associated RhoGEF" EXACT [UniProtKB:Q6ZSZ5] xref: EMBL:AAH77721.1 xref: EMBL:BAA25447.1 xref: EMBL:BAC86801.1 xref: UniProtKB:O60274 xref: UniProtKB:Q6DD92 xref: UniProtKB:Q6ZSZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017024 ! ARHGEF18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0063562 ! ARHGI_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0063563 ! ARHGI_HUMAN-Phosphothreonine212 relationship: transforms_into CCO:B0063564 ! ARHGI_HUMAN-Phosphoserine733 relationship: transforms_into CCO:B0063565 ! ARHGI_HUMAN-Phosphoserine1101 relationship: transforms_into CCO:B0063566 ! ARHGI_HUMAN-Phosphoserine1103 relationship: transforms_into CCO:B0063567 ! ARHGI_HUMAN-Phosphoserine1124 relationship: transforms_into CCO:B0063568 ! ARHGI_HUMAN-Phosphoserine1130 [Term] id: CCO:B0057061 name: TSH1_HUMAN def: "Teashirt homolog 1" [UniProtKB:Q6ZSZ6] synonym: "Antigen NY-CO-33" EXACT [UniProtKB:Q6ZSZ6] synonym: "Serologically defined colon cancer antigen 33" EXACT [UniProtKB:Q6ZSZ6] xref: EMBL:AAC18047.1 xref: EMBL:BAC86800.1 xref: EMBL:BAD97265.1 xref: EMBL:BAE06124.1 xref: UniProtKB:O60534 xref: UniProtKB:Q4LE29 xref: UniProtKB:Q53EU4 xref: UniProtKB:Q6ZSZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020370 ! TSHZ1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057062 name: TBCD9_HUMAN def: "TBC1 domain family member 9" [UniProtKB:Q6ZT07] xref: EMBL:BAA74905.2 xref: EMBL:BAC86789.1 xref: UniProtKB:O94958 xref: UniProtKB:Q6ZT07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020184 ! TBC1D9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071235 ! TBCD9_HUMAN-Phosphoserine997 [Term] id: CCO:B0057063 name: Q6ZT25_HUMAN def: "cDNA FLJ45023 fis, clone BRAWH3017180, highly similar to Diacylglycerol kinase, zeta (EC 2.7.1.107)" [UniProtKB:Q6ZT25] xref: EMBL:BAC86770.1 xref: UniProtKB:Q6ZT25 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057064 name: Q6ZT36_HUMAN def: "cDNA FLJ45002 fis, clone BRAWH3011577, moderately similar to Zinc finger protein 175" [UniProtKB:Q6ZT36] xref: EMBL:BAC86759.1 xref: UniProtKB:Q6ZT36 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057065 name: Q6ZT60_HUMAN def: "cDNA FLJ44934 fis, clone BRAMY3017920, highly similar to Active breakpoint cluster region-related protein" [UniProtKB:Q6ZT60] xref: EMBL:BAC86734.1 xref: UniProtKB:Q6ZT60 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057066 name: Q6ZT62_HUMAN def: "cDNA FLJ44925 fis, clone BRAMY3014613, highly similar to Homo sapiens SH3-domain binding protein 1 (SH3BP1)" [UniProtKB:Q6ZT62] xref: EMBL:BAC86732.1 xref: UniProtKB:Q6ZT62 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057067 name: ZN826_HUMAN def: "Zinc finger protein 826" [UniProtKB:Q6ZT77] xref: EMBL:BAC86717.1 xref: UniProtKB:Q6ZT77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020954 ! ZNF826_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057068 name: Q6ZT94_HUMAN def: "cDNA FLJ44848 fis, clone BRACE3051621, highly similar to Polycystin" [UniProtKB:Q6ZT94] xref: EMBL:BAC86699.1 xref: UniProtKB:Q6ZT94 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057069 name: Q6ZT97_HUMAN xref: UniProtKB:Q6ZT97 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057070 name: Q6ZTJ5_HUMAN def: "cDNA FLJ44592 fis, clone BLADE2002310, highly similar to Homo sapiens SH3-domain binding protein 1 (SH3BP1)" [UniProtKB:Q6ZTJ5] xref: EMBL:BAC86592.1 xref: UniProtKB:Q6ZTJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057071 name: Q6ZTP8_HUMAN xref: UniProtKB:Q6ZTP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057072 name: Q6ZTY0_HUMAN def: "cDNA FLJ44128 fis, clone THYMU2007060, weakly similar to Mus musculus Cdc42 GTPase-activating protein mRNA" [UniProtKB:Q6ZTY0] xref: EMBL:BAC86447.1 xref: UniProtKB:Q6ZTY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057073 name: Q6ZTY7_HUMAN def: "cDNA FLJ44113 fis, clone TESTI4046487, highly similar to Mus musculus plexin A1 (Plxna1)" [UniProtKB:Q6ZTY7] xref: EMBL:BAC86440.1 xref: UniProtKB:Q6ZTY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057074 name: Q6ZU68_HUMAN def: "cDNA FLJ43962 fis, clone TESTI4016822, highly similar to Protein phosphatase inhibitor 2" [UniProtKB:Q6ZU68] xref: EMBL:BAC86358.1 xref: UniProtKB:Q6ZU68 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0057075 name: Q6ZUK8_HUMAN def: "cDNA FLJ43608 fis, clone SPLEN2012624" [UniProtKB:Q6ZUK8] xref: EMBL:BAC86214.1 xref: UniProtKB:Q6ZUK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057076 name: Q6ZUL6_HUMAN def: "cDNA FLJ43577 fis, clone SKMUS2006394, weakly similar to Mus musculus ankyrin repeat-containing protein Asb-4 mRNA" [UniProtKB:Q6ZUL6] xref: EMBL:BAC86204.1 xref: UniProtKB:Q6ZUL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057077 name: Q6ZUP3_HUMAN def: "cDNA FLJ43494 fis, clone PEBLM2000170, moderately similar to Sprouty homolog 3" [UniProtKB:Q6ZUP3] xref: EMBL:BAC86177.1 xref: UniProtKB:Q6ZUP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0057078 name: Q6ZUQ0_HUMAN def: "cDNA FLJ43466 fis, clone OCBBF2036743, weakly similar to ZINC FINGER PROTEIN 133" [UniProtKB:Q6ZUQ0] xref: EMBL:BAC86169.1 xref: UniProtKB:Q6ZUQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057079 name: Q6ZUZ8_HUMAN xref: UniProtKB:Q6ZUZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057080 name: Q6ZV39_HUMAN def: "cDNA FLJ43034 fis, clone BRTHA3001721, highly similar to Homo sapiens BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) (BRF1)" [UniProtKB:Q6ZV39] xref: EMBL:BAC86024.1 xref: UniProtKB:Q6ZV39 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0057081 name: YB020_HUMAN def: "Uncharacterized protein FLJ42986" [UniProtKB:Q6ZV50] xref: EMBL:BAC86013.1 xref: UniProtKB:Q6ZV50 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057082 name: BCRL1_HUMAN def: "Putative BCR-like protein 1" [UniProtKB:Q6ZV63] xref: EMBL:BAC86000.1 xref: UniProtKB:Q6ZV63 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057083 name: FGD6_HUMAN def: "FYVE, RhoGEF and PH domain-containing protein 6" [UniProtKB:Q6ZV73] synonym: "Zinc finger FYVE domain-containing protein 24" EXACT [UniProtKB:Q6ZV73] xref: EMBL:AAH13319.1 xref: EMBL:BAA92052.1 xref: EMBL:BAA92600.1 xref: EMBL:BAC85990.1 xref: EMBL:BAC87464.1 xref: EMBL:CAD98096.1 xref: UniProtKB:Q6ZR53 xref: UniProtKB:Q6ZV73 xref: UniProtKB:Q7Z2Z7 xref: UniProtKB:Q96D44 xref: UniProtKB:Q9NUR8 xref: UniProtKB:Q9P2I5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017789 ! FGD6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002156 ! regulation of Cdc42 GTPase activity relationship: transforms_into CCO:B0066182 ! FGD6_HUMAN-Phosphoserine515 relationship: transforms_into CCO:B0066183 ! FGD6_HUMAN-Phosphoserine721 [Term] id: CCO:B0057084 name: Q6ZVJ0_HUMAN def: "cDNA FLJ42525 fis, clone BRACE3001391, highly similar to Polycystin" [UniProtKB:Q6ZVJ0] xref: EMBL:BAC85871.1 xref: UniProtKB:Q6ZVJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057085 name: Q6ZVN1_HUMAN xref: UniProtKB:Q6ZVN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057086 name: Q6ZVX3_HUMAN def: "cDNA FLJ41975 fis, clone SKNMC2006998, moderately similar to PROTEIN PHOSPHATASE INHIBITOR 1" [UniProtKB:Q6ZVX3] xref: EMBL:BAC85737.1 xref: UniProtKB:Q6ZVX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057087 name: ASB18_HUMAN def: "Ankyrin repeat and SOCS box-containing protein 18" [UniProtKB:Q6ZVZ8] synonym: "ASB-18" EXACT [UniProtKB:Q6ZVZ8] xref: EMBL:BAC85710.1 xref: UniProtKB:Q6ZVZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017064 ! ASB18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057088 name: SYDE1_HUMAN def: "Rho GTPase-activating protein SYDE1" [UniProtKB:Q6ZW31] synonym: "Protein syd-1 homolog 1" EXACT [UniProtKB:Q6ZW31] synonym: "Synapse defective protein 1 homolog 1" EXACT [UniProtKB:Q6ZW31] xref: EMBL:AAH18942.2 xref: EMBL:AAH29926.1 xref: EMBL:BAB14612.1 xref: EMBL:BAC85676.1 xref: EMBL:EAW84462.1 xref: EMBL:EAW84463.1 xref: UniProtKB:Q6ZW31 xref: UniProtKB:Q7L2I8 xref: UniProtKB:Q8N6J2 xref: UniProtKB:Q9H8K4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020084 ! SYDE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001689 ! activation of Rho GTPase activity relationship: transforms_into CCO:B0071025 ! SYDE1_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0071026 ! SYDE1_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0071027 ! SYDE1_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0071028 ! SYDE1_HUMAN-Phosphothreonine246 relationship: transforms_into CCO:B0071029 ! SYDE1_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0071030 ! SYDE1_HUMAN-Phosphoserine681 relationship: transforms_into CCO:B0071031 ! SYDE1_HUMAN-Phosphoserine683 [Term] id: CCO:B0057089 name: Q6ZW62_HUMAN def: "cDNA FLJ41554 fis, clone COLON2005772, highly similar to Homo sapiens candidate taste receptor T2R14 gene" [UniProtKB:Q6ZW62] xref: EMBL:BAC85643.1 xref: UniProtKB:Q6ZW62 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057090 name: PKHM3_HUMAN def: "Pleckstrin homology domain-containing family M member 3" [UniProtKB:Q6ZWE6] xref: EMBL:AAH20812.1 xref: EMBL:BAC85557.1 xref: UniProtKB:Q6ZWE6 xref: UniProtKB:Q8WW68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019421 ! PLEKHM3_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057091 name: TF2H5_HUMAN def: "General transcription factor IIH subunit 5" [UniProtKB:Q6ZYL4] synonym: "General transcription factor IIH polypeptide 5" EXACT [UniProtKB:Q6ZYL4] synonym: "TFB5 ortholog" EXACT [UniProtKB:Q6ZYL4] synonym: "TFIIH basal transcription factor complex TTD-A subunit" EXACT [UniProtKB:Q6ZYL4] xref: EMBL:AAH56906.1 xref: EMBL:AAH60317.1 xref: EMBL:CAG25512.1 xref: EMBL:CAH70241.1 xref: UniProtKB:Q0P5V8 xref: UniProtKB:Q6ZYL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020239 ! GTF2H5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071362 ! TF2H5_HUMAN-Phosphothreonine69 [Term] id: CCO:B0057092 name: RAPH1_HUMAN def: "Ras-associated and pleckstrin homology domains-containing protein 1" [UniProtKB:Q70E73] synonym: "Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein" EXACT [UniProtKB:Q70E73] synonym: "Lamellipodin" EXACT [UniProtKB:Q70E73] synonym: "PREL-2" EXACT [UniProtKB:Q70E73] synonym: "Proline-rich EVH1 ligand 2" EXACT [UniProtKB:Q70E73] synonym: "Protein RMO1" EXACT [UniProtKB:Q70E73] synonym: "RAPH1" EXACT [UniProtKB:Q70E73] xref: EMBL:AAS16935.1 xref: EMBL:AAS16936.1 xref: EMBL:AAS82582.1 xref: EMBL:AAY14676.1 xref: EMBL:BAB21772.1 xref: EMBL:BAB69020.1 xref: EMBL:CAE48361.1 xref: UniProtKB:Q70E73 xref: UniProtKB:Q96Q37 xref: UniProtKB:Q9C0I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019621 ! RAPH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069734 ! RAPH1_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0069735 ! RAPH1_HUMAN-Phosphoserine610 relationship: transforms_into CCO:B0069736 ! RAPH1_HUMAN-Phosphoserine827 relationship: transforms_into CCO:B0069737 ! RAPH1_HUMAN-Phosphothreonine830 relationship: transforms_into CCO:B0069738 ! RAPH1_HUMAN-Phosphoserine853 relationship: transforms_into CCO:B0069739 ! RAPH1_HUMAN-Phosphoserine860 relationship: transforms_into CCO:B0069740 ! RAPH1_HUMAN-Phosphoserine894 relationship: transforms_into CCO:B0069741 ! RAPH1_HUMAN-Phosphoserine965 relationship: transforms_into CCO:B0069742 ! RAPH1_HUMAN-Phosphothreonine974 relationship: transforms_into CCO:B0069743 ! RAPH1_HUMAN-Phosphoserine1154 [Term] id: CCO:B0057093 name: CR3L2_HUMAN def: "cAMP-responsive element-binding protein 3-like protein 2" [UniProtKB:Q70SY1] synonym: "BBF2 human homolog on chromosome 7" EXACT [UniProtKB:Q70SY1] xref: EMBL:AAH63666.1 xref: EMBL:AAI10814.1 xref: EMBL:BAD18659.1 xref: EMBL:CAD79342.1 xref: EMBL:CAD79347.1 xref: EMBL:EAL24050.1 xref: UniProtKB:Q6P454 xref: UniProtKB:Q6ZMR6 xref: UniProtKB:Q70SY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017447 ! CREB3L2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0064460 ! CR3L2_HUMAN-Phosphoserine191 [Term] id: CCO:B0057094 name: Q711G2_HUMAN def: "Nucleoside/nucleotide receptor" [UniProtKB:Q711G2] xref: EMBL:CAC87811.1 xref: UniProtKB:Q711G2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021205 ! P2Y2-like_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057095 name: Q712M9_HUMAN def: "Serotonin receptor 5-HT4" [UniProtKB:Q712M9] xref: EMBL:CAC79538.1 xref: UniProtKB:Q712M9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021206 ! htr4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057096 name: CENPU_HUMAN def: "Centromere protein U" [UniProtKB:Q71F23] synonym: "CENP-50" EXACT [UniProtKB:Q71F23] synonym: "CENP-U" EXACT [UniProtKB:Q71F23] synonym: "CENP-U(50)" EXACT [UniProtKB:Q71F23] synonym: "Interphase centromere complex protein 24" EXACT [UniProtKB:Q71F23] synonym: "KSHV latent nuclear antigen-interacting protein 1" EXACT [UniProtKB:Q71F23] synonym: "MLF1-interacting protein" EXACT [UniProtKB:Q71F23] synonym: "Polo-box-interacting protein 1" EXACT [UniProtKB:Q71F23] xref: EMBL:AAH31520.1 xref: EMBL:AAI07745.1 xref: EMBL:AAQ05290.1 xref: EMBL:AAQ08228.1 xref: EMBL:BAB15665.1 xref: EMBL:CAG33657.1 xref: UniProtKB:Q32Q71 xref: UniProtKB:Q71F23 xref: UniProtKB:Q9H5G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017333 ! MLF1IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064288 ! CENPU_HUMAN-Phosphothreonine78 relationship: transforms_into CCO:B0064289 ! CENPU_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0064290 ! CENPU_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0064291 ! CENPU_HUMAN-Phosphothreonine110 relationship: transforms_into CCO:B0064292 ! CENPU_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0064293 ! CENPU_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0064294 ! CENPU_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0064295 ! CENPU_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0064296 ! CENPU_HUMAN-Phosphoserine229 [Term] id: CCO:B0057097 name: Q71SP6_HUMAN def: "K-ras protein (K-ras p21 protein)" [UniProtKB:Q71SP6] xref: EMBL:AAF91482.1 xref: EMBL:ABS10683.1 xref: EMBL:ABS10684.1 xref: UniProtKB:Q71SP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005434 ! KRAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057098 name: MED25_HUMAN def: "Mediator of RNA polymerase II transcription subunit 25" [UniProtKB:Q71SY5] synonym: "Activator interaction domain 1 protein" EXACT [UniProtKB:Q71SY5] synonym: "Activator-recruited cofactor 92 kDa component" EXACT [UniProtKB:Q71SY5] synonym: "ARC92" EXACT [UniProtKB:Q71SY5] synonym: "Mediator complex subunit 25" EXACT [UniProtKB:Q71SY5] synonym: "p78" EXACT [UniProtKB:Q71SY5] xref: EMBL:AAD15565.1 xref: EMBL:AAG15589.1 xref: EMBL:AAH24312.2 xref: EMBL:AAH65297.1 xref: EMBL:AAM20739.1 xref: EMBL:AAS45401.1 xref: EMBL:CAB66680.1 xref: EMBL:CAE84581.1 xref: EMBL:EAW52546.1 xref: UniProtKB:O95783 xref: UniProtKB:Q6P143 xref: UniProtKB:Q6QMH5 xref: UniProtKB:Q707U4 xref: UniProtKB:Q71SY5 xref: UniProtKB:Q8TB55 xref: UniProtKB:Q9H0L5 xref: UniProtKB:Q9HB34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018598 ! MED25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057099 name: Q71U75_HUMAN def: "MSTP058" [UniProtKB:Q71U75] xref: EMBL:AAO15304.1 xref: UniProtKB:Q71U75 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057100 name: Q71V81_HUMAN def: "Vasoactive intestinal polypeptide receptor 2" [UniProtKB:Q71V81] xref: EMBL:AAC09171.1 xref: UniProtKB:Q71V81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021207 ! VIP2R_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057101 name: Q71VD1_HUMAN def: "Reverse transcriptase" [UniProtKB:Q71VD1] xref: EMBL:AAB71672.1 xref: UniProtKB:Q71VD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021077 ! pol_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057102 name: Q75MN6_HUMAN def: "Putative uncharacterized protein MLL3" [UniProtKB:Q75MN6] xref: EMBL:AAS00364.1 xref: UniProtKB:Q75MN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014832 ! MLL3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057103 name: NOL8_HUMAN def: "Nucleolar protein 8" [UniProtKB:Q76FK4] synonym: "Nucleolar protein Nop132" EXACT [UniProtKB:Q76FK4] xref: EMBL:AAH13788.2 xref: EMBL:BAA91356.1 xref: EMBL:BAA91479.1 xref: EMBL:BAB14229.1 xref: EMBL:BAB14857.1 xref: EMBL:BAB15003.1 xref: EMBL:BAC99315.1 xref: EMBL:BAD12268.1 xref: EMBL:CAC12712.1 xref: EMBL:CAI16204.1 xref: EMBL:CAI16205.1 xref: EMBL:CAI16206.1 xref: EMBL:CAI16207.1 xref: EMBL:CAI16208.1 xref: EMBL:CAI16209.1 xref: UniProtKB:Q5TCC7 xref: UniProtKB:Q5TCC8 xref: UniProtKB:Q5TCD3 xref: UniProtKB:Q5TCD5 xref: UniProtKB:Q5TCD6 xref: UniProtKB:Q5TCD7 xref: UniProtKB:Q76D35 xref: UniProtKB:Q76FK4 xref: UniProtKB:Q7L3E2 xref: UniProtKB:Q9H586 xref: UniProtKB:Q9H795 xref: UniProtKB:Q9H7W7 xref: UniProtKB:Q9H9J6 xref: UniProtKB:Q9NWA4 xref: UniProtKB:Q9NWM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018818 ! NOL8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0001254 ! positive regulation of cell growth relationship: transforms_into CCO:B0068767 ! NOL8_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0068768 ! NOL8_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0068769 ! NOL8_HUMAN-Phosphothreonine302 relationship: transforms_into CCO:B0068770 ! NOL8_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0068771 ! NOL8_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0068772 ! NOL8_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0068773 ! NOL8_HUMAN-Phosphothreonine381 relationship: transforms_into CCO:B0068774 ! NOL8_HUMAN-Phosphoserine801 relationship: transforms_into CCO:B0068775 ! NOL8_HUMAN-Phosphoserine837 relationship: transforms_into CCO:B0068776 ! NOL8_HUMAN-Phosphoserine838 relationship: transforms_into CCO:B0068777 ! NOL8_HUMAN-Phosphoserine843 relationship: transforms_into CCO:B0068778 ! NOL8_HUMAN-Phosphoserine845 relationship: transforms_into CCO:B0068779 ! NOL8_HUMAN-Phosphothreonine888 relationship: transforms_into CCO:B0068780 ! NOL8_HUMAN-Phosphoserine890 relationship: transforms_into CCO:B0068781 ! NOL8_HUMAN-Phosphoserine1036 relationship: transforms_into CCO:B0068782 ! NOL8_HUMAN-Phosphoserine1082 relationship: transforms_into CCO:B0068783 ! NOL8_HUMAN-Phosphoserine1083 relationship: transforms_into CCO:B0068784 ! NOL8_HUMAN-Phosphoserine1084 relationship: transforms_into CCO:B0068785 ! NOL8_HUMAN-Phosphoserine1099 [Term] id: CCO:B0057104 name: Q76KX8_HUMAN def: "Zinc finger protein 534." [UniProtKB:Q76KX8] xref: EMBL:BAD13516.1 xref: UniProtKB:Q76KX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021209 ! ZNF534_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057105 name: ASXL2_HUMAN def: "Putative Polycomb group protein ASXL2" [UniProtKB:Q76L83] synonym: "Additional sex combs-like protein 2" EXACT [UniProtKB:Q76L83] xref: EMBL:AAH42999.1 xref: EMBL:AAY14841.1 xref: EMBL:BAA91889.1 xref: EMBL:BAB21776.2 xref: EMBL:BAD00086.1 xref: EMBL:BAD00088.1 xref: EMBL:CAI45930.1 xref: UniProtKB:Q53TC9 xref: UniProtKB:Q5H9U4 xref: UniProtKB:Q76L81 xref: UniProtKB:Q76L83 xref: UniProtKB:Q86XM1 xref: UniProtKB:Q9C0H8 xref: UniProtKB:Q9NV67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017086 ! ASXL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063634 ! ASXL2_HUMAN-Phosphoserine137 relationship: transforms_into CCO:B0063635 ! ASXL2_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0063636 ! ASXL2_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0063637 ! ASXL2_HUMAN-Phosphoserine517 relationship: transforms_into CCO:B0063638 ! ASXL2_HUMAN-Phosphoserine834 relationship: transforms_into CCO:B0063639 ! ASXL2_HUMAN-Phosphoserine845 [Term] id: CCO:B0057106 name: Q76L88_HUMAN def: "Putative G-protein coupled receptor" [UniProtKB:Q76L88] xref: EMBL:BAB89335.2 xref: UniProtKB:Q76L88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021210 ! GPCR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057107 name: Q76LB3_HUMAN xref: UniProtKB:Q76LB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057108 name: ATS13_HUMAN def: "A disintegrin and metalloproteinase with thrombospondin motifs 13 precursor" [UniProtKB:Q76LX8] synonym: "ADAM-TS 13" EXACT [UniProtKB:Q76LX8] synonym: "ADAM-TS13" EXACT [UniProtKB:Q76LX8] synonym: "ADAMTS-13" EXACT [UniProtKB:Q76LX8] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q76LX8] synonym: "von Willebrand factor-cleaving protease" EXACT [UniProtKB:Q76LX8] synonym: "vWF-cleaving protease" EXACT [UniProtKB:Q76LX8] synonym: "vWF-CP" EXACT [UniProtKB:Q76LX8] xref: EMBL:AAL11095.1 xref: EMBL:AAL17652.1 xref: EMBL:AAQ88485.1 xref: EMBL:ABD72606.1 xref: EMBL:BAB69487.2 xref: EMBL:CAB66743.1 xref: EMBL:CAC83682.1 xref: EMBL:CAD12729.1 xref: EMBL:CAI12850.1 xref: EMBL:CAI12851.1 xref: EMBL:CAI12852.1 xref: EMBL:CAI17248.1 xref: EMBL:CAI17256.1 xref: EMBL:CAI17257.1 xref: EMBL:CAI17258.1 xref: UniProtKB:Q6UY16 xref: UniProtKB:Q710F6 xref: UniProtKB:Q711T8 xref: UniProtKB:Q76LX8 xref: UniProtKB:Q96L37 xref: UniProtKB:Q9H0G3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017103 ! ADAMTS13_human relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:I0015985 ! adamts13-vwf-7 protein cleavage relationship: participates_in CCO:I0019180 ! adamts13-vwf-1 protein cleavage relationship: participates_in CCO:I0019305 ! adamts13-vwf protein cleavage relationship: participates_in CCO:I0019307 ! adamts13-vwf-8 protein cleavage relationship: participates_in CCO:I0019308 ! adamts13-vwf-9 protein cleavage relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0057109 name: VKIND_HUMAN def: "Protein very KIND" [UniProtKB:Q76NI1] synonym: "Cerebral protein 9" EXACT [UniProtKB:Q76NI1] synonym: "Kinase non-catalytic C-lobe domain-containing protein 1" EXACT [UniProtKB:Q76NI1] synonym: "KIND domain-containing protein 1" EXACT [UniProtKB:Q76NI1] synonym: "Ras-GEF domain-containing family member 2" EXACT [UniProtKB:Q76NI1] xref: EMBL:BAB21859.1 xref: EMBL:BAB71561.1 xref: EMBL:BAB85005.1 xref: EMBL:BAD12625.1 xref: EMBL:BAD18397.1 xref: EMBL:CAI17339.1 xref: UniProtKB:Q5T233 xref: UniProtKB:Q6ZNH8 xref: UniProtKB:Q76NI1 xref: UniProtKB:Q8TEE5 xref: UniProtKB:Q96LV7 xref: UniProtKB:Q9C095 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020453 ! KNDC1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0071812 ! VKIND_HUMAN-Phosphoserine982 [Term] id: CCO:B0057110 name: Q7KYU8_HUMAN def: "PDE4C-426" [UniProtKB:Q7KYU8] xref: EMBL:AAB96876.1 xref: UniProtKB:Q7KYU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057111 name: SND1_HUMAN def: "Staphylococcal nuclease domain-containing protein 1" [UniProtKB:Q7KZF4] synonym: "100 kDa coactivator" EXACT [UniProtKB:Q7KZF4] synonym: "EBNA2 coactivator p100" EXACT [UniProtKB:Q7KZF4] synonym: "p100 co-activator" EXACT [UniProtKB:Q7KZF4] synonym: "Tudor domain-containing protein 11" EXACT [UniProtKB:Q7KZF4] xref: EMBL:AAA80488.1 xref: EMBL:AAH17180.3 xref: EMBL:AAP88787.1 xref: UniProtKB:Q13122 xref: UniProtKB:Q7KZF4 xref: UniProtKB:Q96AG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019962 ! SND1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001122 ! RNA interference relationship: transforms_into CCO:B0070679 ! SND1_HUMAN-Phosphotyrosine109 relationship: transforms_into CCO:B0070680 ! SND1_HUMAN-Phosphothreonine429 relationship: transforms_into CCO:B0070681 ! SND1_HUMAN-Phosphoserine781 relationship: transforms_into CCO:B0070682 ! SND1_HUMAN-Phosphotyrosine908 [Term] id: CCO:B0057112 name: YA043_HUMAN def: "Transmembrane protein LOC653160" [UniProtKB:Q7L0L9] xref: EMBL:AAH42172.1 xref: UniProtKB:Q7L0L9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0071899 ! YA043_HUMAN-Phosphoserine14 [Term] id: CCO:B0057113 name: RHOU_HUMAN def: "Rho-related GTP-binding protein RhoU" [UniProtKB:Q7L0Q8] synonym: "CDC42-like GTPase 1" EXACT [UniProtKB:Q7L0Q8] synonym: "GTP-binding protein-like 1" EXACT [UniProtKB:Q7L0Q8] synonym: "Rho GTPase-like protein ARHU" EXACT [UniProtKB:Q7L0Q8] synonym: "Ryu GTPase" EXACT [UniProtKB:Q7L0Q8] synonym: "Wnt-1 responsive Cdc42 homolog 1" EXACT [UniProtKB:Q7L0Q8] synonym: "WRCH-1" EXACT [UniProtKB:Q7L0Q8] xref: EMBL:AAG46058.1 xref: EMBL:AAH40076.1 xref: EMBL:AAK83340.1 xref: EMBL:AAL54874.1 xref: EMBL:AAL99390.1 xref: EMBL:ABD48870.1 xref: EMBL:ABD48871.1 xref: EMBL:ABD48872.1 xref: EMBL:ABD48873.1 xref: EMBL:ABD48874.1 xref: EMBL:ABD48875.1 xref: EMBL:BAB18638.1 xref: EMBL:BAB86361.1 xref: EMBL:BAD92748.1 xref: EMBL:BAF82660.1 xref: EMBL:CAC00584.1 xref: EMBL:EAW69885.1 xref: UniProtKB:B1AKN1 xref: UniProtKB:Q59FE9 xref: UniProtKB:Q7L0Q8 xref: UniProtKB:Q8TDQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019736 ! RHOU_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057114 name: Q7L1K8_HUMAN def: "TBC1D2 protein" [UniProtKB:Q7L1K8] synonym: "TBC1 domain family, member 2" EXACT [UniProtKB:Q7L1K8] synonym: "TBC1 domain family, member 2, isoform CRA_f" EXACT [UniProtKB:Q7L1K8] xref: EMBL:AAH28918.1 xref: EMBL:CAI13894.1 xref: EMBL:EAW58887.1 xref: UniProtKB:Q7L1K8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020186 ! TBC1D2_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057115 name: BZW1_HUMAN def: "Basic leucine zipper and W2 domain-containing protein 1" [UniProtKB:Q7L1Q6] synonym: "Protein Orf" EXACT [UniProtKB:Q7L1Q6] xref: EMBL:AAH01804.1 xref: EMBL:AAH26303.1 xref: EMBL:AAX93286.1 xref: EMBL:BAA02795.2 xref: EMBL:CAA94180.1 xref: UniProtKB:Q14281 xref: UniProtKB:Q15394 xref: UniProtKB:Q7L1Q6 xref: UniProtKB:Q9BUY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017192 ! BZW1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064017 ! BZW1_HUMAN-Phosphoserine411 relationship: transforms_into CCO:B0064018 ! BZW1_HUMAN-Phosphoserine413 [Term] id: CCO:B0057116 name: ZN765_HUMAN def: "Zinc finger protein 765" [UniProtKB:Q7L2R6] xref: EMBL:AAH01610.2 xref: EMBL:AAH17357.1 xref: EMBL:EAW72134.1 xref: UniProtKB:Q7L2R6 xref: UniProtKB:Q9BV49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021054 ! ZNF765_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057117 name: Q7L3H5_HUMAN def: "LIM domain kinase 2 (LIM domain kinase 2, isoform CRA_b)" [UniProtKB:Q7L3H5] xref: EMBL:AAH13051.1 xref: EMBL:EAW59956.1 xref: UniProtKB:Q7L3H5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021212 ! LIMK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002057 ! regulation of phosphorylation [Term] id: CCO:B0057118 name: ZN771_HUMAN def: "Zinc finger protein 771" [UniProtKB:Q7L3S4] synonym: "Mesenchymal stem cell protein DSC43" EXACT [UniProtKB:Q7L3S4] xref: EMBL:AAF65445.1 xref: EMBL:AAH11870.2 xref: EMBL:AAH26192.2 xref: UniProtKB:Q7L3S4 xref: UniProtKB:Q8TAQ7 xref: UniProtKB:Q9NYI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020930 ! ZNF771_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057119 name: RRAGA_HUMAN def: "Ras-related GTP-binding protein A" [UniProtKB:Q7L523] synonym: "Adenovirus E3 14.7 kDa-interacting protein 1" EXACT [UniProtKB:Q7L523] synonym: "FIP-1" EXACT [UniProtKB:Q7L523] synonym: "Rag A" EXACT [UniProtKB:Q7L523] synonym: "RagA" EXACT [UniProtKB:Q7L523] xref: EMBL:AAB63255.1 xref: EMBL:AAH06433.1 xref: EMBL:AAH09990.1 xref: EMBL:CAA62131.1 xref: EMBL:CAH72136.1 xref: UniProtKB:O00290 xref: UniProtKB:Q15347 xref: UniProtKB:Q7L523 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019792 ! RRAGA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008071 ! phosphoprotein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015847 ! rraga-rragc physical interaction relationship: participates_in CCO:I0016330 ! rraga-rragc-3 physical interaction relationship: participates_in CCO:I0016331 ! rraga-rragd-3 physical interaction relationship: participates_in CCO:I0016334 ! rragc-rraga-4 physical interaction relationship: participates_in CCO:I0016335 ! rragd-rraga-4 physical interaction relationship: participates_in CCO:I0017937 ! rraga-rragc-2 physical interaction relationship: participates_in CCO:I0017938 ! rraga-rragd-2 physical interaction relationship: participates_in CCO:I0017939 ! rragc-rraga-5 physical interaction relationship: participates_in CCO:I0017940 ! rraga-rragc-4 physical interaction relationship: participates_in CCO:I0017941 ! rragc-rraga-6 physical interaction relationship: participates_in CCO:I0018098 ! rraga-rragc-1 physical interaction relationship: participates_in CCO:I0018099 ! rraga-rragd-1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002614 ! positive regulation of cytolysis [Term] id: CCO:B0057120 name: DOK3_HUMAN def: "Docking protein 3" [UniProtKB:Q7L591] synonym: "Downstream of tyrosine kinase 3" EXACT [UniProtKB:Q7L591] xref: EMBL:AAH04564.2 xref: EMBL:AAH04867.1 xref: EMBL:BAB15399.1 xref: EMBL:BAC04986.1 xref: UniProtKB:Q7L591 xref: UniProtKB:Q8N864 xref: UniProtKB:Q9BQB3 xref: UniProtKB:Q9H666 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017603 ! DOK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0064848 ! DOK3_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0064849 ! DOK3_HUMAN-Phosphotyrosine381 [Term] id: CCO:B0057121 name: ZN627_HUMAN def: "Zinc finger protein 627" [UniProtKB:Q7L945] xref: EMBL:AAB81084.1 xref: EMBL:AAH06279.2 xref: EMBL:AAH69232.2 xref: EMBL:AAH98416.1 xref: EMBL:BAC11240.1 xref: UniProtKB:O14846 xref: UniProtKB:Q4KMP9 xref: UniProtKB:Q6NT81 xref: UniProtKB:Q7L945 xref: UniProtKB:Q9BRG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020864 ! ZNF627_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057122 name: JHD2B_HUMAN def: "JmjC domain-containing histone demethylation protein 2B" [UniProtKB:Q7LBC6] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q7LBC6] synonym: "Jumonji domain-containing protein 1B" EXACT [UniProtKB:Q7LBC6] synonym: "Nuclear protein 5qNCA" EXACT [UniProtKB:Q7LBC6] xref: EMBL:AAF63765.1 xref: EMBL:AAH00539.2 xref: EMBL:AAH01202.1 xref: EMBL:AAK13499.1 xref: EMBL:BAA83034.2 xref: UniProtKB:Q7LBC6 xref: UniProtKB:Q9BVH6 xref: UniProtKB:Q9BW93 xref: UniProtKB:Q9BZ52 xref: UniProtKB:Q9NYF4 xref: UniProtKB:Q9UPS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018360 ! JMJD1B_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067205 ! JHD2B_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0067206 ! JHD2B_HUMAN-Phosphoserine773 relationship: transforms_into CCO:B0067207 ! JHD2B_HUMAN-Phosphoserine779 relationship: transforms_into CCO:B0067208 ! JHD2B_HUMAN-Phosphoserine798 [Term] id: CCO:B0057123 name: GRP2_HUMAN def: "RAS guanyl-releasing protein 2" [UniProtKB:Q7LDG7] synonym: "Calcium and DAG-regulated guanine nucleotide exchange factor I" EXACT [UniProtKB:Q7LDG7] synonym: "CalDAG-GEFI" EXACT [UniProtKB:Q7LDG7] synonym: "Cdc25-like protein" EXACT [UniProtKB:Q7LDG7] synonym: "F25B3.3 kinase-like protein" EXACT [UniProtKB:Q7LDG7] synonym: "HCDC25L" EXACT [UniProtKB:Q7LDG7] xref: EMBL:AAC79698.1 xref: EMBL:AAD12741.1 xref: EMBL:AAF07219.1 xref: EMBL:AAF07220.1 xref: EMBL:AAI17152.1 xref: EMBL:CAA73005.1 xref: EMBL:EAW74281.1 xref: UniProtKB:O00538 xref: UniProtKB:Q7LDG7 xref: UniProtKB:Q9UL65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018076 ! RASGRP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0066631 ! GRP2_HUMAN-Phosphoserine117 [Term] id: CCO:B0057124 name: NLRC3_HUMAN def: "Protein NLRC3" [UniProtKB:Q7RTR2] synonym: "CARD15-like protein" EXACT [UniProtKB:Q7RTR2] synonym: "Caterpiller protein 16.2" EXACT [UniProtKB:Q7RTR2] synonym: "CLR16.2" EXACT [UniProtKB:Q7RTR2] synonym: "Nucleotide-binding oligomerization domain protein 3" EXACT [UniProtKB:Q7RTR2] xref: EMBL:AAM22459.1 xref: EMBL:AAM22460.1 xref: EMBL:AAT48367.1 xref: EMBL:BAB84935.1 xref: EMBL:BAC03412.1 xref: EMBL:DAA01245.1 xref: UniProtKB:Q5EY36 xref: UniProtKB:Q7RTR2 xref: UniProtKB:Q8NF48 xref: UniProtKB:Q8NI01 xref: UniProtKB:Q8NI02 xref: UniProtKB:Q8TEL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018804 ! NLRC3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0057125 name: T2R42_HUMAN def: "Taste receptor type 2 member 42" [UniProtKB:Q7RTR8] synonym: "T2R42" EXACT [UniProtKB:Q7RTR8] synonym: "T2R55" EXACT [UniProtKB:Q7RTR8] xref: EMBL:AAU21149.1 xref: EMBL:DAA01206.1 xref: UniProtKB:Q645X0 xref: UniProtKB:Q7RTR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020101 ! TAS2R42_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057126 name: BHLH8_HUMAN def: "Class B basic helix-loop-helix protein 8" [UniProtKB:Q7RTS1] synonym: "bHLHB8" EXACT [UniProtKB:Q7RTS1] synonym: "MIST-1" EXACT [UniProtKB:Q7RTS1] synonym: "Muscle, intestine and stomach expression 1" EXACT [UniProtKB:Q7RTS1] xref: EMBL:AAI13395.1 xref: EMBL:AAI13397.1 xref: EMBL:DAA01056.1 xref: UniProtKB:Q14DE4 xref: UniProtKB:Q7RTS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017149 ! BHLHB8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0057127 name: PTF1A_HUMAN def: "Pancreas transcription factor 1 subunit alpha" [UniProtKB:Q7RTS3] synonym: "bHLH transcription factor p48" EXACT [UniProtKB:Q7RTS3] synonym: "p48 DNA-binding subunit of transcription factor PTF1" EXACT [UniProtKB:Q7RTS3] synonym: "Pancreas-specific transcription factor 1a" EXACT [UniProtKB:Q7RTS3] synonym: "PTF1-p48" EXACT [UniProtKB:Q7RTS3] xref: EMBL:AAG09441.1 xref: EMBL:CAI12668.1 xref: EMBL:DAA01052.1 xref: UniProtKB:Q7RTS3 xref: UniProtKB:Q9HC25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019538 ! PTF1A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:B0057128 name: SSX9_HUMAN def: "Protein SSX9" [UniProtKB:Q7RTT3] xref: EMBL:CAI40264.1 xref: EMBL:DAA00376.1 xref: UniProtKB:Q7RTT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020057 ! SSX9_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057129 name: SSX8_HUMAN def: "Protein SSX8" [UniProtKB:Q7RTT4] xref: EMBL:DAA00375.1 xref: UniProtKB:A6NJM6 xref: UniProtKB:Q7RTT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020056 ! SSX8_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057130 name: SSX7_HUMAN def: "Protein SSX7" [UniProtKB:Q7RTT5] xref: EMBL:CAI41147.1 xref: EMBL:DAA00374.1 xref: UniProtKB:Q7RTT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020055 ! SSX7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057131 name: SSX6_HUMAN def: "Protein SSX6" [UniProtKB:Q7RTT6] xref: EMBL:CAI40525.1 xref: EMBL:CAI42940.1 xref: EMBL:DAA00373.1 xref: UniProtKB:Q7RTT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020054 ! SSX6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057132 name: Q7RTU0_HUMAN def: "Transcription factor 24." [UniProtKB:Q7RTU0] xref: EMBL:DAA00306.1 xref: UniProtKB:Q7RTU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057133 name: TCF23_HUMAN def: "Transcription factor 23" [UniProtKB:Q7RTU1] xref: EMBL:DAA00305.1 xref: UniProtKB:Q7RTU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020215 ! TCF23_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057134 name: OLIG3_HUMAN def: "Oligodendrocyte transcription factor 3" [UniProtKB:Q7RTU3] synonym: "bHLHB7" EXACT [UniProtKB:Q7RTU3] synonym: "Class B basic helix-loop-helix protein 7" EXACT [UniProtKB:Q7RTU3] synonym: "Oligo3" EXACT [UniProtKB:Q7RTU3] xref: EMBL:AAH51352.1 xref: EMBL:BAC04768.1 xref: EMBL:CAI20348.1 xref: EMBL:DAA00303.1 xref: UniProtKB:Q7RTU3 xref: UniProtKB:Q8N8Q0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019044 ! OLIG3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057135 name: BHL42_HUMAN def: "Class B basic helix-loop-helix factor 42" [UniProtKB:Q7RTU4] synonym: "bHLHF42" EXACT [UniProtKB:Q7RTU4] xref: EMBL:DAA00302.1 xref: UniProtKB:A8MSH6 xref: UniProtKB:Q7RTU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017145 ! BHLHF42_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057136 name: ASCL5_HUMAN def: "Achaete-scute homolog 5" [UniProtKB:Q7RTU5] xref: EMBL:DAA00301.1 xref: UniProtKB:Q7RTU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017079 ! ASCL5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057137 name: SCX_HUMAN def: "Basic helix-loop-helix transcription factor scleraxis" [UniProtKB:Q7RTU7] xref: EMBL:DAA00239.1 xref: UniProtKB:Q7RTU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019855 ! SCXA_human relationship: encoded_by CCO:G0019856 ! SCXB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057138 name: ZN367_HUMAN def: "Zinc finger protein 367" [UniProtKB:Q7RTV3] synonym: "C2H2 zinc finger protein ZFF29" EXACT [UniProtKB:Q7RTV3] xref: EMBL:AAI26142.1 xref: EMBL:AAS66302.1 xref: EMBL:AAS66303.1 xref: EMBL:CAI39622.1 xref: EMBL:DAA00067.1 xref: UniProtKB:Q6Q7C8 xref: UniProtKB:Q7RTV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020721 ! ZNF367_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0072116 ! ZN367_HUMAN-Phosphoserine310 [Term] id: CCO:B0057139 name: TS1R3_HUMAN def: "Taste receptor type 1 member 3 precursor" [UniProtKB:Q7RTX0] synonym: "Sweet taste receptor T1R3" EXACT [UniProtKB:Q7RTX0] xref: EMBL:BAC05873.1 xref: EMBL:CAI23184.1 xref: EMBL:DAA00013.1 xref: UniProtKB:Q5TA49 xref: UniProtKB:Q7RTX0 xref: UniProtKB:Q8NGW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020367 ! TAS1R3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_function CCO:F0005058 ! sweet taste receptor activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057140 name: TS1R1_HUMAN def: "Taste receptor type 1 member 1 precursor" [UniProtKB:Q7RTX1] synonym: "G-protein coupled receptor 70" EXACT [UniProtKB:Q7RTX1] xref: EMBL:AAL91358.1 xref: EMBL:AAL91359.1 xref: EMBL:AAL91360.1 xref: EMBL:AAL91361.1 xref: EMBL:BAC05845.1 xref: EMBL:CAI16073.1 xref: EMBL:CAI16074.1 xref: EMBL:CAI16076.1 xref: EMBL:DAA00012.1 xref: UniProtKB:Q5SY22 xref: UniProtKB:Q5SY24 xref: UniProtKB:Q7RTX1 xref: UniProtKB:Q8NGZ7 xref: UniProtKB:Q8TDJ7 xref: UniProtKB:Q8TDJ8 xref: UniProtKB:Q8TDJ9 xref: UniProtKB:Q8TDK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020365 ! TAS1R1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057141 name: ZN720_HUMAN def: "Putative protein ZNF720" [UniProtKB:Q7Z2F6] xref: EMBL:AAH18134.1 xref: EMBL:AAH55408.1 xref: EMBL:BAC87562.1 xref: EMBL:EAW52108.1 xref: UniProtKB:Q6ZQX1 xref: UniProtKB:Q7Z2F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020918 ! ZNF720_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057142 name: Q7Z2I8_HUMAN def: "Putative uncharacterized protein DKFZp686A24188" [UniProtKB:Q7Z2I8] synonym: "Putative uncharacterized protein DKFZp686B23188" EXACT [UniProtKB:Q7Z2I8] xref: EMBL:CAD97801.1 xref: EMBL:CAD98053.1 xref: UniProtKB:Q7Z2I8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021213 ! DKFZp686A24188_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057143 name: Q7Z2K2_HUMAN def: "Transforming gene product TGAT" [UniProtKB:Q7Z2K2] xref: EMBL:BAC79392.1 xref: UniProtKB:Q7Z2K2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021214 ! tgat_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057144 name: ZN551_HUMAN def: "Zinc finger protein 551" [UniProtKB:Q7Z340] synonym: "Zinc finger protein KOX23" EXACT [UniProtKB:Q7Z340] xref: EMBL:AAH05868.1 xref: EMBL:BAC03625.1 xref: EMBL:CAA36580.1 xref: EMBL:CAD98037.1 xref: UniProtKB:P17034 xref: UniProtKB:Q7Z340 xref: UniProtKB:Q8N246 xref: UniProtKB:Q9BRY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011801 ! ZNF551_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072149 ! ZN551_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0072150 ! ZN551_HUMAN-Phosphoserine12 [Term] id: CCO:B0057145 name: HDX_HUMAN def: "Highly divergent homeobox" [UniProtKB:Q7Z353] xref: EMBL:AAI01721.1 xref: EMBL:AAI01723.1 xref: EMBL:BAB70886.1 xref: EMBL:CAD98024.1 xref: EMBL:CAI42056.1 xref: EMBL:CAI42095.1 xref: EMBL:CAI42096.1 xref: EMBL:EAW98572.1 xref: EMBL:EAW98573.1 xref: UniProtKB:Q5JZB4 xref: UniProtKB:Q7Z353 xref: UniProtKB:Q96NK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018112 ! HDX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057146 name: ZN550_HUMAN def: "Zinc finger protein 550" [UniProtKB:Q7Z398] xref: EMBL:AAC24606.1 xref: EMBL:AAH34810.1 xref: EMBL:AAH53858.1 xref: EMBL:CAD97977.1 xref: UniProtKB:O43337 xref: UniProtKB:Q7Z398 xref: UniProtKB:Q7Z6D7 xref: UniProtKB:Q8NE45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020811 ! ZNF550_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072148 ! ZN550_HUMAN-Phosphotyrosine259 [Term] id: CCO:B0057147 name: Q7Z3D9_HUMAN def: "Putative uncharacterized protein DKFZp686K1352" [UniProtKB:Q7Z3D9] xref: EMBL:CAD97931.1 xref: UniProtKB:Q7Z3D9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021215 ! DKFZp686K1352_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057148 name: Q7Z3E4_HUMAN def: "Putative uncharacterized protein DKFZp686N1286" [UniProtKB:Q7Z3E4] synonym: "tRNA aspartic acid methyltransferase 1 variant 8" EXACT [UniProtKB:Q7Z3E4] xref: EMBL:ACA05981.1 xref: EMBL:CAD97925.1 xref: UniProtKB:Q7Z3E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021216 ! DKFZp686N1286_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0057149 name: GP155_HUMAN def: "Integral membrane protein GPR155" [UniProtKB:Q7Z3F1] synonym: "G-protein coupled receptor PGR22" EXACT [UniProtKB:Q7Z3F1] xref: EMBL:AAH28730.1 xref: EMBL:AAH35037.1 xref: EMBL:AAO85040.1 xref: EMBL:AAY14707.1 xref: EMBL:AAY24218.1 xref: EMBL:BAB71170.1 xref: EMBL:BAC03609.1 xref: EMBL:BAC04835.1 xref: EMBL:CAD97915.1 xref: EMBL:CAH10683.1 xref: UniProtKB:Q4G0Y6 xref: UniProtKB:Q53SJ3 xref: UniProtKB:Q53TA8 xref: UniProtKB:Q69YG8 xref: UniProtKB:Q7Z3F1 xref: UniProtKB:Q86SP9 xref: UniProtKB:Q8N261 xref: UniProtKB:Q8N639 xref: UniProtKB:Q8N8K3 xref: UniProtKB:Q96MV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017978 ! GPR155_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0066528 ! GP155_HUMAN-Phosphotyrosine451 [Term] id: CCO:B0057150 name: Q7Z3I0_HUMAN def: "Putative uncharacterized protein DKFZp313E1411" [UniProtKB:Q7Z3I0] xref: EMBL:CAD97883.1 xref: UniProtKB:Q7Z3I0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020845 ! ZNF595_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057151 name: ZN572_HUMAN def: "Zinc finger protein 572" [UniProtKB:Q7Z3I7] xref: EMBL:BAC04529.1 xref: EMBL:CAD97876.1 xref: UniProtKB:Q7Z3I7 xref: UniProtKB:Q8N1Q0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020829 ! ZNF572_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057152 name: MIER3_HUMAN def: "Mesoderm induction early response protein 3" [UniProtKB:Q7Z3K6] synonym: "Mi-er3" EXACT [UniProtKB:Q7Z3K6] xref: EMBL:AAH41348.2 xref: EMBL:BAC04117.1 xref: EMBL:CAD97846.1 xref: EMBL:CAE45951.2 xref: EMBL:CAH18102.1 xref: EMBL:CAH18665.1 xref: EMBL:CAI56710.1 xref: UniProtKB:Q5CZI0 xref: UniProtKB:Q68CS3 xref: UniProtKB:Q6MZS7 xref: UniProtKB:Q7Z3K6 xref: UniProtKB:Q86YG8 xref: UniProtKB:Q8NA13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018622 ! MIER3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068183 ! MIER3_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0068184 ! MIER3_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0068185 ! MIER3_HUMAN-Phosphoserine168 [Term] id: CCO:B0057153 name: Q7Z3R3_HUMAN def: "Putative uncharacterized protein DKFZp686J1593" [UniProtKB:Q7Z3R3] xref: EMBL:CAD97766.1 xref: UniProtKB:Q7Z3R3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021218 ! DKFZp686J1593_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057154 name: OR2W3_HUMAN def: "Olfactory receptor 2W3" [UniProtKB:Q7Z3T1] synonym: "Olfactory receptor OR1-49" EXACT [UniProtKB:Q7Z3T1] xref: EMBL:BAC06162.1 xref: EMBL:CAD97674.1 xref: EMBL:DAA04854.1 xref: UniProtKB:Q6IF06 xref: UniProtKB:Q7Z3T1 xref: UniProtKB:Q8NG86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019125 ! OR2W3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057155 name: ZFY16_HUMAN def: "Zinc finger FYVE domain-containing protein 16" [UniProtKB:Q7Z3T8] synonym: "Endofin" EXACT [UniProtKB:Q7Z3T8] synonym: "Endosome-associated FYVE domain protein" EXACT [UniProtKB:Q7Z3T8] xref: EMBL:AAH30808.1 xref: EMBL:AAH32227.1 xref: EMBL:AAL30772.1 xref: EMBL:BAA20764.2 xref: EMBL:CAD89968.1 xref: EMBL:CAD97666.1 xref: UniProtKB:O15023 xref: UniProtKB:Q7LAU7 xref: UniProtKB:Q7Z3T8 xref: UniProtKB:Q86T69 xref: UniProtKB:Q8N5L3 xref: UniProtKB:Q8NEK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020599 ! ZFYVE16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001243 ! regulation of endocytosis relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: transforms_into CCO:B0072023 ! ZFY16_HUMAN-Phosphotyrosine219 relationship: transforms_into CCO:B0072024 ! ZFY16_HUMAN-Phosphotyrosine221 relationship: transforms_into CCO:B0072025 ! ZFY16_HUMAN-Phosphoserine446 relationship: transforms_into CCO:B0072026 ! ZFY16_HUMAN-Phosphoserine815 relationship: transforms_into CCO:B0072027 ! ZFY16_HUMAN-Phosphoserine845 relationship: transforms_into CCO:B0072028 ! ZFY16_HUMAN-Phosphoserine939 relationship: transforms_into CCO:B0072029 ! ZFY16_HUMAN-Phosphoserine946 relationship: transforms_into CCO:B0072030 ! ZFY16_HUMAN-Phosphothreonine1209 relationship: transforms_into CCO:B0072031 ! ZFY16_HUMAN-Phosphoserine1210 [Term] id: CCO:B0057156 name: ZN571_HUMAN def: "Zinc finger protein 571" [UniProtKB:Q7Z3V5] xref: EMBL:AAF29031.2 xref: EMBL:AAH40591.1 xref: EMBL:AAI13871.1 xref: EMBL:CAD97643.1 xref: UniProtKB:Q2HIY0 xref: UniProtKB:Q3ZCU3 xref: UniProtKB:Q7Z3V5 xref: UniProtKB:Q9NZX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020828 ! ZNF571_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057157 name: MYCPP_HUMAN def: "C-myc promoter-binding protein" [UniProtKB:Q7Z401] synonym: "DENN domain-containing protein 4A" EXACT [UniProtKB:Q7Z401] xref: EMBL:AAH41706.1 xref: EMBL:AAQ10514.1 xref: EMBL:BAC03648.1 xref: EMBL:CAA45013.1 xref: EMBL:CAD89960.1 xref: UniProtKB:Q14655 xref: UniProtKB:Q7Z401 xref: UniProtKB:Q86T77 xref: UniProtKB:Q8IVX2 xref: UniProtKB:Q8NB93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018694 ! DENND4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068367 ! MYCPP_HUMAN-Phosphoserine728 relationship: transforms_into CCO:B0068368 ! MYCPP_HUMAN-Phosphoserine731 relationship: transforms_into CCO:B0068369 ! MYCPP_HUMAN-Phosphoserine1281 relationship: transforms_into CCO:B0068370 ! MYCPP_HUMAN-Phosphoserine1511 relationship: transforms_into CCO:B0068371 ! MYCPP_HUMAN-Phosphoserine1587 [Term] id: CCO:B0057158 name: MAVS_HUMAN def: "Mitochondrial antiviral-signaling protein" [UniProtKB:Q7Z434] synonym: "CARD adapter inducing interferon-beta" EXACT [UniProtKB:Q7Z434] synonym: "Cardif" EXACT [UniProtKB:Q7Z434] synonym: "Interferon-beta promoter stimulator protein 1" EXACT [UniProtKB:Q7Z434] synonym: "IPS-1" EXACT [UniProtKB:Q7Z434] synonym: "Putative NF-kappa-B-activating protein 031N" EXACT [UniProtKB:Q7Z434] synonym: "Virus-induced-signaling adapter" EXACT [UniProtKB:Q7Z434] xref: EMBL:AAH44952.1 xref: EMBL:AAZ80417.1 xref: EMBL:ABA19229.1 xref: EMBL:ABA54890.1 xref: EMBL:BAA86585.1 xref: EMBL:BAB14684.1 xref: EMBL:BAC77356.1 xref: EMBL:BAC85473.1 xref: EMBL:BAC85734.1 xref: EMBL:CAI11041.1 xref: EMBL:CAI18851.1 xref: UniProtKB:Q3I0Y2 xref: UniProtKB:Q5T7I6 xref: UniProtKB:Q7Z434 xref: UniProtKB:Q86VY7 xref: UniProtKB:Q9H1H3 xref: UniProtKB:Q9H4Y1 xref: UniProtKB:Q9H8D3 xref: UniProtKB:Q9ULE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018574 ! MAVS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017780 ! ddx58-mavs-1 physical interaction relationship: participates_in CCO:I0017781 ! ikbke-mavs-1 physical interaction relationship: participates_in CCO:I0017782 ! chuk-mavs-1 physical interaction relationship: participates_in CCO:I0017783 ! ikbkb-mavs-1 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0068006 ! MAVS_HUMAN-Phosphothreonine147 relationship: transforms_into CCO:B0068007 ! MAVS_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0068008 ! MAVS_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0068009 ! MAVS_HUMAN-Phosphothreonine163 relationship: transforms_into CCO:B0068010 ! MAVS_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0068011 ! MAVS_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0068012 ! MAVS_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0068013 ! MAVS_HUMAN-Phosphothreonine234 relationship: transforms_into CCO:B0068014 ! MAVS_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0068015 ! MAVS_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0068016 ! MAVS_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0068017 ! MAVS_HUMAN-Phosphoserine373 relationship: transforms_into CCO:B0068018 ! MAVS_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0068019 ! MAVS_HUMAN-Phosphothreonine398 [Term] id: CCO:B0057159 name: PK1L2_HUMAN def: "Polycystic kidney disease protein 1-like 2 precursor" [UniProtKB:Q7Z442] synonym: "PC1-like 2 protein" EXACT [UniProtKB:Q7Z442] synonym: "Polycystin-1L2" EXACT [UniProtKB:Q7Z442] xref: EMBL:AAH04562.1 xref: EMBL:AAH14157.1 xref: EMBL:AAO32796.1 xref: EMBL:AAQ73173.1 xref: EMBL:BAB67772.1 xref: EMBL:BAC05222.1 xref: EMBL:BAC86906.1 xref: EMBL:BAD18529.1 xref: UniProtKB:Q6UEE1 xref: UniProtKB:Q6ZN46 xref: UniProtKB:Q6ZSP2 xref: UniProtKB:Q7Z442 xref: UniProtKB:Q8N1H9 xref: UniProtKB:Q96CL2 xref: UniProtKB:Q96Q08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019406 ! PKD1L2_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057160 name: PK1L3_HUMAN def: "Polycystic kidney disease protein 1-like 3 precursor" [UniProtKB:Q7Z443] synonym: "PC1-like 3 protein" EXACT [UniProtKB:Q7Z443] synonym: "Polycystin-1L3" EXACT [UniProtKB:Q7Z443] xref: EMBL:AAO32798.1 xref: UniProtKB:Q7Z443 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019407 ! PKD1L3_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057161 name: RASE_HUMAN def: "GTPase ERas precursor" [UniProtKB:Q7Z444] synonym: "E-Ras" EXACT [UniProtKB:Q7Z444] synonym: "Embryonic stem cell-expressed Ras" EXACT [UniProtKB:Q7Z444] xref: EMBL:AAI01643.1 xref: EMBL:AAI01645.1 xref: EMBL:BAC76997.1 xref: UniProtKB:Q7Z444 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019626 ! ERAS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069753 ! RASE_HUMAN-Cysteine methyl ester230 [Term] id: CCO:B0057162 name: NPHP3_HUMAN def: "Nephrocystin-3" [UniProtKB:Q7Z494] xref: EMBL:AAH68082.1 xref: EMBL:AAP83423.1 xref: EMBL:AAP83424.1 xref: EMBL:AAP83425.1 xref: EMBL:BAB70891.1 xref: EMBL:BAB71038.1 xref: EMBL:BAC02709.1 xref: EMBL:BAC04268.1 xref: EMBL:CAH18321.1 xref: EMBL:CAI46200.2 xref: EMBL:CAI46202.1 xref: UniProtKB:Q5JPE3 xref: UniProtKB:Q5JPE6 xref: UniProtKB:Q68D99 xref: UniProtKB:Q6NVH3 xref: UniProtKB:Q7Z492 xref: UniProtKB:Q7Z493 xref: UniProtKB:Q7Z494 xref: UniProtKB:Q8N9R2 xref: UniProtKB:Q8NCM5 xref: UniProtKB:Q96N70 xref: UniProtKB:Q96NK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018836 ! NPHP3_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002849 ! maintenance of organ identity [Term] id: CCO:B0057163 name: Q7Z4E8_HUMAN def: "MSTP090" [UniProtKB:Q7Z4E8] xref: EMBL:AAQ13613.1 xref: UniProtKB:Q7Z4E8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021219 ! MST090_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057164 name: Q7Z4J1_HUMAN def: "Nonintegrin platelet receptor for type I collagen" [UniProtKB:Q7Z4J1] xref: EMBL:AAQ02646.1 xref: UniProtKB:Q7Z4J1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0057165 name: Q7Z4J5_HUMAN def: "Runt-related transcription factor 1; translocated to, 1 (Cyclin D-related)" [UniProtKB:Q7Z4J5] synonym: "Core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related" EXACT [UniProtKB:Q7Z4J5] synonym: "Runt-related transcription factor 1; translocated to, 1 (Cyclin D-related), isoform CRA_e" EXACT [UniProtKB:Q7Z4J5] xref: EMBL:AAH67078.2 xref: EMBL:AAP88873.1 xref: EMBL:EAW91685.1 xref: UniProtKB:Q6NXH1 xref: UniProtKB:Q7Z4J5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018679 ! RUNX1T1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057166 name: Q7Z4R1_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q7Z4R1] xref: EMBL:AAP97699.1 xref: UniProtKB:Q7Z4R1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057167 name: ZN438_HUMAN def: "Zinc finger protein 438" [UniProtKB:Q7Z4V0] xref: EMBL:AAI01623.1 xref: EMBL:AAI04758.1 xref: EMBL:AAP97298.1 xref: EMBL:ABC86954.1 xref: EMBL:ABC86955.1 xref: EMBL:BAD18510.1 xref: EMBL:CAH56317.1 xref: EMBL:CAI13438.1 xref: UniProtKB:Q5T426 xref: UniProtKB:Q658Q4 xref: UniProtKB:Q6ZN65 xref: UniProtKB:Q7Z4V0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020750 ! ZNF438_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057168 name: Q7Z4W6_HUMAN def: "Preprotachykinin B" [UniProtKB:Q7Z4W6] xref: EMBL:AAP97264.1 xref: UniProtKB:Q7Z4W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000752 ! tachykinin signaling pathway [Term] id: CCO:B0057169 name: Q7Z4W7_HUMAN def: "Rab-related GTP-binding protein" [UniProtKB:Q7Z4W7] xref: EMBL:AAP97262.1 xref: UniProtKB:Q7Z4W7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057170 name: Q7Z516_HUMAN def: "Nuclear receptor co-repressor" [UniProtKB:Q7Z516] xref: EMBL:AAP97166.1 xref: UniProtKB:Q7Z516 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057171 name: Q7Z555_HUMAN xref: UniProtKB:Q7Z555 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0057172 name: Q7Z566_HUMAN def: "Activating transcription factor 3 delta Zip2c (Activating transcription factor 3)" [UniProtKB:Q7Z566] xref: EMBL:AAP93896.1 xref: EMBL:CAH72654.1 xref: UniProtKB:Q7Z566 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004114 ! ATF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057173 name: Q7Z567_HUMAN def: "Activating transcription factor 3 delta Zip3 (cDNA FLJ57271, highly similar to Cyclic AMP-dependent transcription factorATF-3)" [UniProtKB:Q7Z567] xref: EMBL:AAP93895.1 xref: EMBL:BAG57579.1 xref: UniProtKB:Q7Z567 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004114 ! ATF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057174 name: Q7Z581_HUMAN def: "G protein-coupled receptor 50 variant c" [UniProtKB:Q7Z581] xref: EMBL:AAM78369.1 xref: UniProtKB:Q7Z581 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021116 ! GPR50_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001956 ! melatonin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057175 name: EMSY_HUMAN def: "Protein EMSY" [UniProtKB:Q7Z589] xref: EMBL:AAF86947.1 xref: EMBL:AAH29375.1 xref: EMBL:AAH33404.1 xref: EMBL:AAL65260.1 xref: EMBL:BAB14627.1 xref: EMBL:BAC11481.1 xref: EMBL:CAD22881.1 xref: UniProtKB:Q4G109 xref: UniProtKB:Q7Z589 xref: UniProtKB:Q8NBU6 xref: UniProtKB:Q8TE50 xref: UniProtKB:Q9H8I9 xref: UniProtKB:Q9NRH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017708 ! EMSY_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065060 ! EMSY_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0065061 ! EMSY_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0065062 ! EMSY_HUMAN-Phosphothreonine262 relationship: transforms_into CCO:B0065063 ! EMSY_HUMAN-Phosphothreonine273 relationship: transforms_into CCO:B0065064 ! EMSY_HUMAN-Phosphothreonine274 relationship: transforms_into CCO:B0065065 ! EMSY_HUMAN-Phosphoserine1130 relationship: transforms_into CCO:B0065066 ! EMSY_HUMAN-Phosphoserine1136 [Term] id: CCO:B0057176 name: AKNA_HUMAN def: "AT-hook-containing transcription factor" [UniProtKB:Q7Z591] xref: EMBL:AAH42202.1 xref: EMBL:AAH55285.1 xref: EMBL:AAK83024.1 xref: EMBL:AAU34186.1 xref: EMBL:AAU34190.1 xref: EMBL:AAU34191.1 xref: EMBL:AAU34192.1 xref: EMBL:BAB15721.1 xref: EMBL:BAB84866.1 xref: EMBL:BAB85554.1 xref: EMBL:BAC85132.1 xref: EMBL:BAC86459.1 xref: EMBL:BAD18725.1 xref: EMBL:CAI16861.1 xref: EMBL:CAI16862.2 xref: EMBL:CAI16863.1 xref: EMBL:CAM23638.1 xref: UniProtKB:Q05BK5 xref: UniProtKB:Q5T535 xref: UniProtKB:Q5T536 xref: UniProtKB:Q5T537 xref: UniProtKB:Q64FX6 xref: UniProtKB:Q64FX7 xref: UniProtKB:Q64FX8 xref: UniProtKB:Q64FY2 xref: UniProtKB:Q6ZMK0 xref: UniProtKB:Q6ZNL2 xref: UniProtKB:Q6ZTX0 xref: UniProtKB:Q7Z591 xref: UniProtKB:Q8TET1 xref: UniProtKB:Q8TF33 xref: UniProtKB:Q96RR9 xref: UniProtKB:Q9H7P7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016947 ! AKNA_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065558 ! AKNA_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0065559 ! AKNA_HUMAN-Phosphoserine848 [Term] id: CCO:B0057177 name: Q7Z598_HUMAN xref: UniProtKB:Q7Z598 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057178 name: HPC14_HUMAN def: "Homeobox protein C14" [UniProtKB:Q7Z5D8] xref: EMBL:AAP76323.1 xref: UniProtKB:Q7Z5D8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057179 name: Q7Z5G6_HUMAN def: "IRF3 protein" [UniProtKB:Q7Z5G6] xref: EMBL:AAH00660.1 xref: UniProtKB:Q7Z5G6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057180 name: RHG22_HUMAN def: "Rho GTPase-activating protein 22" [UniProtKB:Q7Z5H3] synonym: "Rho-type GTPase-activating protein 22" EXACT [UniProtKB:Q7Z5H3] xref: EMBL:AAB51057.1 xref: EMBL:AAI26445.1 xref: EMBL:AAP85632.1 xref: EMBL:BAC87044.1 xref: UniProtKB:A0AVP7 xref: UniProtKB:O00152 xref: UniProtKB:Q6ZSB0 xref: UniProtKB:Q7Z5H3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019722 ! ARHGAP22_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057181 name: VN1R5_HUMAN def: "Vomeronasal type-1 receptor 5" [UniProtKB:Q7Z5H4] synonym: "hGPCR26" EXACT [UniProtKB:Q7Z5H4] synonym: "V1r-like receptor 5" EXACT [UniProtKB:Q7Z5H4] xref: EMBL:AAI26342.1 xref: EMBL:AAI26368.1 xref: EMBL:AAM66756.1 xref: EMBL:AAP85622.1 xref: EMBL:AAP85623.1 xref: EMBL:BAB89321.1 xref: UniProtKB:A0AVG1 xref: UniProtKB:Q7Z5H4 xref: UniProtKB:Q8NEU5 xref: UniProtKB:Q8TDU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020458 ! VN1R5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057182 name: VN1R4_HUMAN def: "Vomeronasal type-1 receptor 4" [UniProtKB:Q7Z5H5] synonym: "hGPCR27" EXACT [UniProtKB:Q7Z5H5] synonym: "V1r-like receptor 4" EXACT [UniProtKB:Q7Z5H5] xref: EMBL:AAI04936.1 xref: EMBL:AAI04940.1 xref: EMBL:AAM66754.1 xref: EMBL:AAP85618.1 xref: EMBL:AAP85619.1 xref: EMBL:AAP85620.1 xref: EMBL:AAP85621.1 xref: EMBL:BAB89322.1 xref: UniProtKB:Q2M3E2 xref: UniProtKB:Q7Z5H5 xref: UniProtKB:Q7Z5H6 xref: UniProtKB:Q7Z5H7 xref: UniProtKB:Q8TDU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020457 ! VN1R4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057183 name: I2BP2_HUMAN def: "Interferon regulatory factor 2-binding protein 2" [UniProtKB:Q7Z5L9] synonym: "IRF-2-binding protein 2" EXACT [UniProtKB:Q7Z5L9] synonym: "IRF-2BP2" EXACT [UniProtKB:Q7Z5L9] xref: EMBL:AAH20516.1 xref: EMBL:AAH28143.1 xref: EMBL:AAH65759.1 xref: EMBL:AAP78944.1 xref: EMBL:AAP78945.1 xref: UniProtKB:Q6P083 xref: UniProtKB:Q7Z5L8 xref: UniProtKB:Q7Z5L9 xref: UniProtKB:Q8N351 xref: UniProtKB:Q8WUH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018204 ! IRF2BP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066975 ! I2BP2_HUMAN-Phosphoserine360 relationship: transforms_into CCO:B0066976 ! I2BP2_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0066977 ! I2BP2_HUMAN-Phosphoserine457 relationship: transforms_into CCO:B0066978 ! I2BP2_HUMAN-Phosphoserine460 [Term] id: CCO:B0057184 name: CPEB2_HUMAN def: "Cytoplasmic polyadenylation element-binding protein 2" [UniProtKB:Q7Z5Q1] synonym: "CPE-binding protein 2" EXACT [UniProtKB:Q7Z5Q1] synonym: "CPE-BP2" EXACT [UniProtKB:Q7Z5Q1] synonym: "hCPEB-2" EXACT [UniProtKB:Q7Z5Q1] xref: EMBL:AAI03940.2 xref: EMBL:AAI03941.1 xref: EMBL:AAI03942.1 xref: EMBL:AAI03943.1 xref: EMBL:AAI05926.1 xref: EMBL:AAP37585.1 xref: EMBL:AAP41553.1 xref: UniProtKB:Q3B8N6 xref: UniProtKB:Q3MI89 xref: UniProtKB:Q3MI90 xref: UniProtKB:Q3MI92 xref: UniProtKB:Q7Z5Q0 xref: UniProtKB:Q7Z5Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017438 ! CPEB2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0057185 name: DPOLN_HUMAN def: "DNA polymerase nu" [UniProtKB:Q7Z5Q5] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q7Z5Q5] xref: EMBL:AAN52116.1 xref: EMBL:AAY43130.1 xref: EMBL:BAD18421.1 xref: UniProtKB:Q4TTW4 xref: UniProtKB:Q6ZNF4 xref: UniProtKB:Q7Z5Q5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017611 ! POLN_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0057186 name: Q7Z5X8_HUMAN def: "DGKZ protein" [UniProtKB:Q7Z5X8] xref: EMBL:AAH08018.1 xref: UniProtKB:Q7Z5X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017573 ! DGKZ_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0057187 name: Q7Z5Y1_HUMAN def: "Upstream stimulatory factor 1 BD" [UniProtKB:Q7Z5Y1] xref: EMBL:BAC78384.1 xref: UniProtKB:Q7Z5Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021220 ! usf1-bd_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057188 name: GP142_HUMAN def: "Probable G-protein coupled receptor 142" [UniProtKB:Q7Z601] synonym: "G-protein coupled receptor PGR2" EXACT [UniProtKB:Q7Z601] xref: EMBL:AAO85134.1 xref: EMBL:AAP72130.1 xref: UniProtKB:Q7Z601 xref: UniProtKB:Q86SL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017969 ! GPR142_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057189 name: GP141_HUMAN def: "Probable G-protein coupled receptor 141" [UniProtKB:Q7Z602] synonym: "G-protein coupled receptor PGR13" EXACT [UniProtKB:Q7Z602] xref: EMBL:AAI20952.1 xref: EMBL:AAI20953.1 xref: EMBL:AAO85050.1 xref: EMBL:AAP72129.1 xref: UniProtKB:Q0VAR5 xref: UniProtKB:Q7Z602 xref: UniProtKB:Q86SP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017968 ! GPR141_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057190 name: ARHG8_HUMAN def: "Neuroepithelial cell-transforming gene 1 protein" [UniProtKB:Q7Z628] synonym: "p65 Net1 proto-oncogene" EXACT [UniProtKB:Q7Z628] synonym: "Rho guanine nucleotide exchange factor 8" EXACT [UniProtKB:Q7Z628] xref: EMBL:AAB08847.1 xref: EMBL:AAB37683.1 xref: EMBL:AAH10285.1 xref: EMBL:AAH53553.1 xref: EMBL:CAA08974.1 xref: UniProtKB:Q12773 xref: UniProtKB:Q7Z628 xref: UniProtKB:Q96D82 xref: UniProtKB:Q99903 xref: UniProtKB:Q9UEN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017018 ! NET1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0063543 ! ARHG8_HUMAN-Phosphoserine100 relationship: transforms_into CCO:B0063544 ! ARHG8_HUMAN-Phosphoserine106 [Term] id: CCO:B0057191 name: Q7Z664_HUMAN def: "Putative uncharacterized protein DKFZp779N0926" [UniProtKB:Q7Z664] xref: EMBL:CAD98014.1 xref: UniProtKB:Q7Z664 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021221 ! DKFZp779N0926_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057192 name: Q7Z670_HUMAN def: "Putative uncharacterized protein DKFZp779E2460" [UniProtKB:Q7Z670] xref: EMBL:CAD97861.1 xref: UniProtKB:Q7Z670 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021222 ! DKFZp779E2460_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057193 name: Q7Z679_HUMAN def: "Putative uncharacterized protein DKFZp779A1451" [UniProtKB:Q7Z679] xref: EMBL:CAD97837.1 xref: UniProtKB:Q7Z679 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021223 ! DKFZp779A1451_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057194 name: SPRE2_HUMAN def: "Sprouty-related, EVH1 domain-containing protein 2" [UniProtKB:Q7Z698] synonym: "Spred-2" EXACT [UniProtKB:Q7Z698] xref: EMBL:AAI11496.1 xref: EMBL:AAP59415.1 xref: UniProtKB:Q2NKX6 xref: UniProtKB:Q7Z698 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020020 ! SPRED2_human relationship: has_function CCO:F0001474 ! stem cell factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0070802 ! SPRE2_HUMAN-Phosphotyrosine228 relationship: transforms_into CCO:B0070803 ! SPRE2_HUMAN-Phosphotyrosine231 [Term] id: CCO:B0057195 name: SPRE1_HUMAN def: "Sprouty-related, EVH1 domain-containing protein 1" [UniProtKB:Q7Z699] synonym: "hSpred1" EXACT [UniProtKB:Q7Z699] synonym: "Spred-1" EXACT [UniProtKB:Q7Z699] xref: EMBL:AAH18015.1 xref: EMBL:AAP59414.1 xref: EMBL:BAC03614.1 xref: UniProtKB:Q05D53 xref: UniProtKB:Q7Z699 xref: UniProtKB:Q8N256 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020019 ! SPRED1_human relationship: has_function CCO:F0001474 ! stem cell factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0057196 name: SRGP1_HUMAN def: "SLIT-ROBO Rho GTPase-activating protein 1" [UniProtKB:Q7Z6B7] synonym: "Rho GTPase-activating protein 13" EXACT [UniProtKB:Q7Z6B7] synonym: "srGAP1" EXACT [UniProtKB:Q7Z6B7] xref: EMBL:AAH53903.1 xref: EMBL:BAA92542.1 xref: EMBL:BAB14714.1 xref: UniProtKB:Q7Z6B7 xref: UniProtKB:Q9H8A3 xref: UniProtKB:Q9P2P2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020037 ! SRGAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070913 ! SRGP1_HUMAN-Phosphoserine906 relationship: transforms_into CCO:B0070914 ! SRGP1_HUMAN-Phosphoserine917 relationship: transforms_into CCO:B0070915 ! SRGP1_HUMAN-Phosphoserine999 relationship: transforms_into CCO:B0070916 ! SRGP1_HUMAN-Phosphothreonine1001 relationship: transforms_into CCO:B0070917 ! SRGP1_HUMAN-Phosphothreonine1004 relationship: transforms_into CCO:B0070918 ! SRGP1_HUMAN-Phosphoserine1005 relationship: transforms_into CCO:B0070919 ! SRGP1_HUMAN-Phosphoserine1008 relationship: transforms_into CCO:B0070920 ! SRGP1_HUMAN-Phosphoserine1010 relationship: transforms_into CCO:B0070921 ! SRGP1_HUMAN-Phosphoserine1029 relationship: transforms_into CCO:B0070922 ! SRGP1_HUMAN-Phosphoserine1032 [Term] id: CCO:B0057197 name: RHG30_HUMAN def: "Rho GTPase-activating protein 30" [UniProtKB:Q7Z6I6] synonym: "Rho-type GTPase-activating protein 30" EXACT [UniProtKB:Q7Z6I6] xref: EMBL:AAH43387.1 xref: EMBL:AAH53688.1 xref: EMBL:BAD18709.1 xref: EMBL:CAD97855.1 xref: EMBL:CAI15373.1 xref: EMBL:CAI15374.1 xref: EMBL:CAI15375.1 xref: UniProtKB:Q5SY52 xref: UniProtKB:Q5SY53 xref: UniProtKB:Q5SY54 xref: UniProtKB:Q6ZML6 xref: UniProtKB:Q7Z3J8 xref: UniProtKB:Q7Z6I6 xref: UniProtKB:Q86XI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019728 ! ARHGAP30_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069993 ! RHG30_HUMAN-Phosphoserine987 relationship: transforms_into CCO:B0069994 ! RHG30_HUMAN-Phosphoserine988 relationship: transforms_into CCO:B0069995 ! RHG30_HUMAN-Phosphoserine996 relationship: transforms_into CCO:B0069996 ! RHG30_HUMAN-Phosphotyrosine1087 [Term] id: CCO:B0057198 name: FGD2_HUMAN def: "FYVE, RhoGEF and PH domain-containing protein 2" [UniProtKB:Q7Z6J4] synonym: "Zinc finger FYVE domain-containing protein 4" EXACT [UniProtKB:Q7Z6J4] xref: EMBL:AAH23645.1 xref: EMBL:AAH53655.1 xref: EMBL:AAH62363.1 xref: EMBL:BAB15746.1 xref: EMBL:BAC04982.1 xref: EMBL:BAC85129.1 xref: EMBL:CAI20471.1 xref: UniProtKB:Q5T8I1 xref: UniProtKB:Q6P6A8 xref: UniProtKB:Q6ZNL5 xref: UniProtKB:Q7Z6J4 xref: UniProtKB:Q8IZ32 xref: UniProtKB:Q8N868 xref: UniProtKB:Q9H7M2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017785 ! FGD2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004648 ! small GTPase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002156 ! regulation of Cdc42 GTPase activity [Term] id: CCO:B0057199 name: RAB44_HUMAN def: "Ras-related protein Rab-44" [UniProtKB:Q7Z6P3] xref: EMBL:CAD92808.1 xref: UniProtKB:Q7Z6P3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019600 ! RAB44_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057200 name: Q7Z6S5_HUMAN def: "TATA box binding protein" [UniProtKB:Q7Z6S5] xref: EMBL:CAD92543.1 xref: UniProtKB:Q7Z6S5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005744 ! TBP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057201 name: Q7Z6S6_HUMAN def: "TATA-box-binding protein" [UniProtKB:Q7Z6S6] xref: EMBL:CAD92542.1 xref: UniProtKB:Q7Z6S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005744 ! TBP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057202 name: Q7Z6T9_HUMAN def: "TBP-like 1" [UniProtKB:Q7Z6T9] xref: EMBL:CAD92518.1 xref: UniProtKB:Q7Z6T9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020190 ! TBPL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057203 name: Q7Z6U0_HUMAN def: "TBP-like 1" [UniProtKB:Q7Z6U0] xref: EMBL:CAD92517.1 xref: UniProtKB:Q7Z6U0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020190 ! TBPL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057204 name: Q7Z6U1_HUMAN def: "TBP-like 1" [UniProtKB:Q7Z6U1] xref: EMBL:CAD92516.1 xref: UniProtKB:Q7Z6U1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020190 ! TBPL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057205 name: Q7Z6U2_HUMAN def: "TBP-like 1" [UniProtKB:Q7Z6U2] xref: EMBL:CAD92515.1 xref: UniProtKB:Q7Z6U2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020190 ! TBPL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057206 name: Q7Z729_HUMAN def: "MZF1 protein" [UniProtKB:Q7Z729] xref: EMBL:AAH53316.1 xref: UniProtKB:Q7Z729 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018706 ! MZF1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057207 name: Q7Z761_HUMAN def: "ZNF169 protein" [UniProtKB:Q7Z761] xref: EMBL:AAH11947.1 xref: UniProtKB:Q7Z761 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020638 ! ZNF169_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057208 name: Q7Z783_HUMAN def: "SPRY2 protein" [UniProtKB:Q7Z783] xref: EMBL:AAH04205.1 xref: UniProtKB:Q7Z783 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0057209 name: TAF8_HUMAN def: "Transcription initiation factor TFIID subunit 8" [UniProtKB:Q7Z7C8] synonym: "hTAFII43" EXACT [UniProtKB:Q7Z7C8] synonym: "Protein taube nuss" EXACT [UniProtKB:Q7Z7C8] synonym: "TBP-associated factor 43 kDa" EXACT [UniProtKB:Q7Z7C8] synonym: "TBP-associated factor 8" EXACT [UniProtKB:Q7Z7C8] synonym: "Transcription initiation factor TFIID 43 kDa subunit" EXACT [UniProtKB:Q7Z7C8] xref: EMBL:AAH33728.1 xref: EMBL:AAI19679.1 xref: EMBL:AAI19680.1 xref: EMBL:AAP47094.1 xref: EMBL:BAB71460.1 xref: EMBL:CAI15202.1 xref: EMBL:CAI15203.1 xref: EMBL:CAI16781.1 xref: EMBL:CAI16782.1 xref: UniProtKB:Q5T0K1 xref: UniProtKB:Q7Z7C8 xref: UniProtKB:Q8N4R9 xref: UniProtKB:Q96M52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020141 ! TAF8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002412 ! regulation of fat cell differentiation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071113 ! TAF8_HUMAN-Phosphothreonine130 [Term] id: CCO:B0057210 name: Q7Z7E1_HUMAN def: "A disintegrin and metalloprotease 33" [UniProtKB:Q7Z7E1] xref: EMBL:AAP15443.1 xref: UniProtKB:Q7Z7E1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0057211 name: Q7Z7E3_HUMAN def: "A disintegrin and metalloprotease 33" [UniProtKB:Q7Z7E3] xref: EMBL:AAP15441.1 xref: UniProtKB:Q7Z7E3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000676 ! metalloendopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0057212 name: Q7Z7E5_HUMAN def: "A disintegrin and metalloprotease 33" [UniProtKB:Q7Z7E5] xref: EMBL:AAP15439.1 xref: UniProtKB:Q7Z7E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway [Term] id: CCO:B0057213 name: MIST_HUMAN def: "Mast cell immunoreceptor signal transducer" [UniProtKB:Q7Z7G1] synonym: "Cytokine-dependent hematopoietic cell linker" EXACT [UniProtKB:Q7Z7G1] xref: EMBL:AAH29887.1 xref: EMBL:BAA96241.1 xref: EMBL:BAC76765.1 xref: UniProtKB:Q05C27 xref: UniProtKB:Q7Z7G1 xref: UniProtKB:Q9P2U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018626 ! MIST_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0068200 ! MIST_HUMAN-Phosphotyrosine69 relationship: transforms_into CCO:B0068201 ! MIST_HUMAN-Phosphotyrosine96 [Term] id: CCO:B0057214 name: CPLX4_HUMAN def: "Complexin-4 precursor" [UniProtKB:Q7Z7G2] synonym: "Complexin IV" EXACT [UniProtKB:Q7Z7G2] synonym: "CPX IV" EXACT [UniProtKB:Q7Z7G2] xref: EMBL:AAI06888.1 xref: EMBL:AAI06889.1 xref: EMBL:AAP41128.1 xref: EMBL:BAC85549.1 xref: EMBL:CAE45797.1 xref: UniProtKB:Q7Z7G2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017440 ! CPLX4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002749 ! regulation of neurotransmitter secretion relationship: transforms_into CCO:B0064451 ! CPLX4_HUMAN-Cysteine methyl ester157 [Term] id: CCO:B0057215 name: ZN467_HUMAN def: "Zinc finger protein 467" [UniProtKB:Q7Z7K2] xref: EMBL:AAH52625.1 xref: UniProtKB:Q7Z7K2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020762 ! ZNF467_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057216 name: Q7Z7K7_HUMAN def: "ZNF850P protein" [UniProtKB:Q7Z7K7] xref: EMBL:AAH52603.1 xref: UniProtKB:Q7Z7K7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021224 ! ZNF850P_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057217 name: Q7Z7L0_HUMAN def: "PMS2L5 protein" [UniProtKB:Q7Z7L0] xref: EMBL:AAH52588.1 xref: UniProtKB:Q7Z7L0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011846 ! PMS2L5_human relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000645 ! mismatch repair [Term] id: CCO:B0057218 name: Q7Z7L4_HUMAN xref: UniProtKB:Q7Z7L4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0057219 name: ZSCA2_HUMAN def: "Zinc finger and SCAN domain-containing protein 2" [UniProtKB:Q7Z7L9] synonym: "Zfp-29" EXACT [UniProtKB:Q7Z7L9] synonym: "Zinc finger protein 29 homolog" EXACT [UniProtKB:Q7Z7L9] xref: EMBL:AAH41620.1 xref: EMBL:AAP36989.1 xref: EMBL:BAA91283.1 xref: EMBL:BAC87537.1 xref: UniProtKB:Q6ZQY9 xref: UniProtKB:Q7Z7L9 xref: UniProtKB:Q9NWU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021008 ! ZSCAN2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057220 name: GP144_HUMAN def: "Probable G-protein coupled receptor 144" [UniProtKB:Q7Z7M1] synonym: "G-protein coupled receptor PGR24" EXACT [UniProtKB:Q7Z7M1] xref: EMBL:AAO85132.1 xref: EMBL:AAP35064.1 xref: EMBL:BAC05829.1 xref: EMBL:CAI10884.1 xref: UniProtKB:Q7Z7M1 xref: UniProtKB:Q86SL4 xref: UniProtKB:Q8NH12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017970 ! GPR144_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057221 name: Q86SE3_HUMAN def: "Putative olfactory receptor" [UniProtKB:Q86SE3] xref: EMBL:AAP32607.1 xref: EMBL:AAP32608.1 xref: EMBL:AAP32609.1 xref: EMBL:AAP32610.1 xref: EMBL:AAP32611.1 xref: EMBL:AAP32612.1 xref: EMBL:AAP32613.1 xref: EMBL:AAP32614.1 xref: EMBL:AAP32615.1 xref: EMBL:AAP32616.1 xref: EMBL:AAP32617.1 xref: EMBL:AAP32618.1 xref: EMBL:AAP32619.1 xref: EMBL:AAP32620.1 xref: EMBL:AAP32621.1 xref: EMBL:AAP32622.1 xref: EMBL:AAP32624.1 xref: EMBL:AAP32625.1 xref: EMBL:AAP32626.1 xref: EMBL:AAP32627.1 xref: EMBL:AAP32628.1 xref: EMBL:AAP32629.1 xref: EMBL:AAP32630.1 xref: EMBL:AAP32631.1 xref: EMBL:AAP32632.1 xref: EMBL:AAP32633.1 xref: EMBL:AAP32634.1 xref: EMBL:AAP32635.1 xref: EMBL:AAP32636.1 xref: EMBL:AAP32637.1 xref: EMBL:AAP32638.1 xref: UniProtKB:Q86SE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057222 name: PCGF5_HUMAN def: "Polycomb group RING finger protein 5" [UniProtKB:Q86SE9] synonym: "RING finger protein 159" EXACT [UniProtKB:Q86SE9] xref: EMBL:AAH07377.1 xref: EMBL:AAH51845.1 xref: EMBL:CAD89905.1 xref: EMBL:CAD91165.1 xref: UniProtKB:Q6PK47 xref: UniProtKB:Q86SE9 xref: UniProtKB:Q86TD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019321 ! PCGF5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057223 name: Q86SF1_HUMAN def: "Putative olfactory receptor" [UniProtKB:Q86SF1] xref: EMBL:AAP32515.1 xref: EMBL:AAP32519.1 xref: EMBL:AAP32525.1 xref: UniProtKB:Q86SF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057224 name: Q86SF3_HUMAN def: "Putative olfactory receptor" [UniProtKB:Q86SF3] xref: EMBL:AAP32481.1 xref: EMBL:AAP32483.1 xref: UniProtKB:Q86SF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057225 name: Q86SG0_HUMAN def: "Putative olfactory receptor" [UniProtKB:Q86SG0] xref: EMBL:AAP32639.1 xref: EMBL:AAP32641.1 xref: EMBL:AAP32644.1 xref: EMBL:AAP32646.1 xref: EMBL:AAP32648.1 xref: EMBL:AAP32649.1 xref: EMBL:AAP32650.1 xref: EMBL:AAP32652.1 xref: EMBL:AAP32655.1 xref: EMBL:AAP32656.1 xref: EMBL:AAP32658.1 xref: EMBL:AAP32659.1 xref: UniProtKB:Q86SG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057226 name: Q86SG9_HUMAN def: "Putative olfactory receptor" [UniProtKB:Q86SG9] xref: EMBL:AAP32575.1 xref: EMBL:AAP32595.1 xref: EMBL:AAP32596.1 xref: EMBL:AAP32597.1 xref: EMBL:AAP32599.1 xref: UniProtKB:Q86SG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057227 name: Q86SI5_HUMAN def: "Putative olfactory receptor" [UniProtKB:Q86SI5] xref: EMBL:AAP32543.1 xref: EMBL:AAP32544.1 xref: EMBL:AAP32545.1 xref: EMBL:AAP32546.1 xref: EMBL:AAP32547.1 xref: EMBL:AAP32548.1 xref: EMBL:AAP32549.1 xref: EMBL:AAP32550.1 xref: EMBL:AAP32551.1 xref: EMBL:AAP32552.1 xref: EMBL:AAP32553.1 xref: EMBL:AAP32554.1 xref: EMBL:AAP32556.1 xref: EMBL:AAP32557.1 xref: EMBL:AAP32558.1 xref: EMBL:AAP32559.1 xref: EMBL:AAP32560.1 xref: EMBL:AAP32562.1 xref: EMBL:AAP32564.1 xref: EMBL:AAP32565.1 xref: EMBL:AAP32566.1 xref: EMBL:AAP32567.1 xref: EMBL:AAP32568.1 xref: EMBL:AAP32569.1 xref: EMBL:AAP32570.1 xref: EMBL:AAP32571.1 xref: EMBL:AAP32572.1 xref: EMBL:AAP32574.1 xref: UniProtKB:Q86SI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057228 name: AMGO2_HUMAN def: "Amphoterin-induced protein 2 precursor" [UniProtKB:Q86SJ2] synonym: "Alivin-1" EXACT [UniProtKB:Q86SJ2] synonym: "AMIGO-2" EXACT [UniProtKB:Q86SJ2] synonym: "DEGA" EXACT [UniProtKB:Q86SJ2] synonym: "Differentially expressed in gastric adenocarcinomas" EXACT [UniProtKB:Q86SJ2] xref: EMBL:AAH14103.2 xref: EMBL:AAH47595.1 xref: EMBL:AAH95477.1 xref: EMBL:AAO48946.1 xref: EMBL:AAR83271.1 xref: EMBL:BAC81188.1 xref: EMBL:BAC81189.1 xref: EMBL:CAH56293.1 xref: UniProtKB:Q4VBP6 xref: UniProtKB:Q7Z4A0 xref: UniProtKB:Q86SJ2 xref: UniProtKB:Q96CN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016960 ! AMIGO2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002151 ! negative regulation of programmed cell death [Term] id: CCO:B0057229 name: MRGRG_HUMAN def: "Mas-related G-protein coupled receptor member G" [UniProtKB:Q86SM5] synonym: "G-protein coupled receptor 169" EXACT [UniProtKB:Q86SM5] xref: EMBL:AAO85095.1 xref: UniProtKB:Q86SM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018655 ! MRGPRG_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057230 name: Q86SP4_HUMAN def: "G protein-coupled receptor PGR14" [UniProtKB:Q86SP4] xref: EMBL:AAO85048.1 xref: UniProtKB:Q86SP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057231 name: GP149_HUMAN def: "Probable G-protein coupled receptor 149" [UniProtKB:Q86SP6] synonym: "G-protein coupled receptor PGR10" EXACT [UniProtKB:Q86SP6] xref: EMBL:AAO85046.1 xref: UniProtKB:Q86SP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017973 ! GPR149_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057232 name: EMR4_HUMAN def: "Putative EGF-like module-containing mucin-like hormone receptor-like 4 precursor" [UniProtKB:Q86SQ3] synonym: "G-protein coupled receptor 127" EXACT [UniProtKB:Q86SQ3] synonym: "G-protein coupled receptor PGR16" EXACT [UniProtKB:Q86SQ3] xref: EMBL:AAO27357.1 xref: EMBL:AAO85062.1 xref: UniProtKB:Q86SP1 xref: UniProtKB:Q86SQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017707 ! EMR4P_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057233 name: GP123_HUMAN def: "Probable G-protein coupled receptor 123" [UniProtKB:Q86SQ6] xref: EMBL:AAO27353.1 xref: EMBL:AAO85076.1 xref: EMBL:BAB47457.1 xref: UniProtKB:A6NG50 xref: UniProtKB:Q5T234 xref: UniProtKB:Q86SN7 xref: UniProtKB:Q86SQ6 xref: UniProtKB:Q96JJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017962 ! GPR123_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057234 name: Q86SR2_HUMAN def: "AZU1 protein" [UniProtKB:Q86SR2] xref: EMBL:AAH44940.1 xref: UniProtKB:Q86SR2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017224 ! AZU1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001655 ! azurophil granule relationship: participates_in CCO:P0002099 ! positive regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002553 ! positive regulation of cell adhesion relationship: participates_in CCO:P0002932 ! positive regulation of interleukin-1 beta biosynthetic process relationship: participates_in CCO:P0002941 ! positive regulation of fractalkine biosynthetic process relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis [Term] id: CCO:B0057235 name: Q86ST5_HUMAN def: "CENTG3 protein" [UniProtKB:Q86ST5] xref: EMBL:AAH44644.1 xref: UniProtKB:Q86ST5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057236 name: KAISO_HUMAN def: "Transcriptional regulator Kaiso" [UniProtKB:Q86T24] synonym: "Zinc finger and BTB domain-containing protein 33" EXACT [UniProtKB:Q86T24] xref: EMBL:AAB54087.1 xref: EMBL:AAH42753.1 xref: EMBL:CAD38715.1 xref: EMBL:CAD91170.1 xref: EMBL:CAD97963.1 xref: EMBL:CAD98016.1 xref: UniProtKB:O00319 xref: UniProtKB:Q7Z361 xref: UniProtKB:Q86T24 xref: UniProtKB:Q8IVP6 xref: UniProtKB:Q8N3P0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018373 ! ZBTB33_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0067250 ! KAISO_HUMAN-Phosphotyrosine442 [Term] id: CCO:B0057237 name: ZN605_HUMAN def: "Zinc finger protein 605" [UniProtKB:Q86T29] xref: EMBL:CAD89946.1 xref: EMBL:CAD91163.1 xref: UniProtKB:Q86T29 xref: UniProtKB:Q86T91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020850 ! ZNF605_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057238 name: Q86TH3_HUMAN def: "Dishevelled, dsh homolog 1 (Drosophila)" [UniProtKB:Q86TH3] xref: EMBL:AAH50454.1 xref: UniProtKB:Q86TH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017645 ! DVL1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057239 name: TAD2B_HUMAN def: "Transcriptional adapter 2-beta" [UniProtKB:Q86TJ2] synonym: "ADA2-beta" EXACT [UniProtKB:Q86TJ2] synonym: "ADA2-like protein beta" EXACT [UniProtKB:Q86TJ2] xref: EMBL:AAH47794.1 xref: EMBL:AAI01335.1 xref: EMBL:AAI01336.1 xref: EMBL:AAI01337.1 xref: EMBL:AAI01338.1 xref: EMBL:CAE46064.1 xref: UniProtKB:A0AUJ8 xref: UniProtKB:A4QMR7 xref: UniProtKB:Q6MZG9 xref: UniProtKB:Q86TJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020129 ! TADA2B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057240 name: ZN554_HUMAN def: "Zinc finger protein 554" [UniProtKB:Q86TJ5] xref: EMBL:AAH00113.1 xref: EMBL:AAH47777.1 xref: EMBL:BAC03814.1 xref: UniProtKB:Q86TJ5 xref: UniProtKB:Q8NAT3 xref: UniProtKB:Q9BWN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020813 ! ZNF554_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057241 name: Q86TP4_HUMAN def: "TCFL5 protein" [UniProtKB:Q86TP4] xref: EMBL:AAH46933.1 xref: UniProtKB:Q86TP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:B0057242 name: Q86TY6_HUMAN def: "Full-length cDNA clone CS0DI055YO20 of Placenta of Homo sapiens (human)" [UniProtKB:Q86TY6] xref: EMBL:CAD62612.1 xref: UniProtKB:Q86TY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057243 name: Q86U13_HUMAN def: "Full-length cDNA clone CS0DF017YJ08 of Fetal brain of Homo sapiens (human)" [UniProtKB:Q86U13] xref: EMBL:CAD62582.1 xref: UniProtKB:Q86U13 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057244 name: LDB1_HUMAN def: "LIM domain-binding protein 1" [UniProtKB:Q86U70] synonym: "Carboxyl-terminal LIM domain-binding protein 2" EXACT [UniProtKB:Q86U70] synonym: "CLIM-2" EXACT [UniProtKB:Q86U70] synonym: "hLdb1" EXACT [UniProtKB:Q86U70] synonym: "LIM domain-binding factor CLIM2" EXACT [UniProtKB:Q86U70] synonym: "Nuclear LIM interactor" EXACT [UniProtKB:Q86U70] xref: EMBL:AAC28341.1 xref: EMBL:AAC77818.1 xref: EMBL:AAH00482.1 xref: EMBL:AAH09246.1 xref: EMBL:AAP35703.1 xref: EMBL:BAA31991.1 xref: EMBL:BAE95402.1 xref: EMBL:CAB45409.1 xref: EMBL:CAH72217.1 xref: UniProtKB:O75479 xref: UniProtKB:O96010 xref: UniProtKB:Q1EQX1 xref: UniProtKB:Q86U70 xref: UniProtKB:Q9UGM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018466 ! LDB1_human relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004370 ! LIM domain binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0015138 ! ldb1-ssbp4 physical interaction relationship: participates_in CCO:I0015419 ! ldb1-lmo3 physical interaction relationship: participates_in CCO:I0015533 ! ldb1-ssbp2 physical interaction relationship: participates_in CCO:I0015600 ! ldb1-tollip physical interaction relationship: participates_in CCO:I0019096 ! atxn1-ldb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002461 ! negative regulation of erythrocyte differentiation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0057245 name: RIP_HUMAN def: "RPA-interacting protein" [UniProtKB:Q86UA6] synonym: "hRIP" EXACT [UniProtKB:Q86UA6] xref: EMBL:AAH04451.1 xref: EMBL:AAH46349.1 xref: EMBL:AAH51849.1 xref: EMBL:AAT80872.1 xref: EMBL:AAT80873.1 xref: EMBL:AAT80874.1 xref: EMBL:AAT80875.1 xref: EMBL:AAT80876.1 xref: EMBL:AAT80877.1 xref: EMBL:AAT80878.1 xref: EMBL:AAX14368.1 xref: EMBL:AAX14369.1 xref: EMBL:AAX14370.1 xref: EMBL:AAX14371.1 xref: EMBL:AAX14372.1 xref: EMBL:AAX14373.1 xref: EMBL:AAX14374.1 xref: EMBL:AAX14375.1 xref: EMBL:AAX14377.1 xref: UniProtKB:Q4G2Y0 xref: UniProtKB:Q4G2Y5 xref: UniProtKB:Q4G2Y8 xref: UniProtKB:Q6B4V9 xref: UniProtKB:Q6B4W0 xref: UniProtKB:Q6B4W1 xref: UniProtKB:Q6B4W4 xref: UniProtKB:Q86UA6 xref: UniProtKB:Q86X49 xref: UniProtKB:Q9BT00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019746 ! RPAIN_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:B0057246 name: ZN329_HUMAN def: "Zinc finger protein 329" [UniProtKB:Q86UD4] xref: EMBL:AAH47501.1 xref: EMBL:BAB14154.1 xref: UniProtKB:Q86UD4 xref: UniProtKB:Q9H9R7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020706 ! ZNF329_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057247 name: TBC26_HUMAN def: "TBC1 domain family member 26" [UniProtKB:Q86UD7] xref: EMBL:AAH28414.1 xref: EMBL:AAH47400.1 xref: EMBL:BAF85233.1 xref: EMBL:BAF98738.1 xref: UniProtKB:A8K929 xref: UniProtKB:Q4G172 xref: UniProtKB:Q86UD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020168 ! TBC1D26_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057248 name: Q86UH2_HUMAN def: "LIM-homeobox 9 protein" [UniProtKB:Q86UH2] synonym: "LIM homeobox 9" EXACT [UniProtKB:Q86UH2] synonym: "LIM homeobox 9, isoform CRA_d" EXACT [UniProtKB:Q86UH2] xref: EMBL:AAI31623.1 xref: EMBL:AAP32471.2 xref: EMBL:CAH71763.1 xref: EMBL:EAW91290.1 xref: UniProtKB:Q86UH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018491 ! LHX9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057249 name: ZFHX4_HUMAN def: "Zinc finger homeobox protein 4" [UniProtKB:Q86UP3] synonym: "ZFH-4" EXACT [UniProtKB:Q86UP3] synonym: "Zinc finger homeodomain protein 4" EXACT [UniProtKB:Q86UP3] xref: EMBL:AAP20225.1 xref: EMBL:BAD18555.1 xref: EMBL:BAE96598.1 xref: UniProtKB:Q18PS0 xref: UniProtKB:Q6ZN20 xref: UniProtKB:Q86UP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020584 ! ZFHX4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0072016 ! ZFHX4_HUMAN-Phosphoserine1892 [Term] id: CCO:B0057250 name: GTD2A_HUMAN def: "General transcription factor II-I repeat domain-containing protein 2A" [UniProtKB:Q86UP8] synonym: "GTF2I repeat domain-containing protein 2A" EXACT [UniProtKB:Q86UP8] synonym: "Transcription factor GTF2IRD2-alpha" EXACT [UniProtKB:Q86UP8] xref: EMBL:AAH47706.1 xref: EMBL:AAH61590.1 xref: EMBL:AAH67859.1 xref: EMBL:AAP14955.1 xref: EMBL:AAQ19673.1 xref: EMBL:AAQ19674.1 xref: EMBL:AAR36865.1 xref: EMBL:AAR36866.1 xref: EMBL:AAR36867.1 xref: EMBL:BAF84120.1 xref: EMBL:CAD38788.2 xref: EMBL:CAD38861.1 xref: UniProtKB:A8K5W6 xref: UniProtKB:Q69G40 xref: UniProtKB:Q6EKI8 xref: UniProtKB:Q6EKI9 xref: UniProtKB:Q6NVW2 xref: UniProtKB:Q6P7N8 xref: UniProtKB:Q86UP8 xref: UniProtKB:Q86WX4 xref: UniProtKB:Q8ND85 xref: UniProtKB:Q8NDE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018088 ! GTF2IRD2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057251 name: ZN589_HUMAN def: "Zinc finger protein 589" [UniProtKB:Q86UQ0] synonym: "Stem cell zinc finger protein 1" EXACT [UniProtKB:Q86UQ0] xref: EMBL:AAD38879.1 xref: EMBL:AAD38880.1 xref: EMBL:AAH05859.2 xref: EMBL:AAH06247.2 xref: EMBL:AAH48798.1 xref: EMBL:AAP14679.1 xref: EMBL:CAI46129.1 xref: EMBL:EAW64856.1 xref: UniProtKB:Q86UC9 xref: UniProtKB:Q86UQ0 xref: UniProtKB:Q9BRI6 xref: UniProtKB:Q9BRY3 xref: UniProtKB:Q9Y611 xref: UniProtKB:Q9Y612 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020841 ! ZNF589_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057252 name: Q86UQ2_HUMAN def: "Paired box 3 splice variant PAX3H" [UniProtKB:Q86UQ2] xref: EMBL:AAP13873.1 xref: UniProtKB:Q86UQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057253 name: Q86UQ3_HUMAN def: "Paired box 3 splice variant PAX3G" [UniProtKB:Q86UQ3] xref: EMBL:AAP13872.1 xref: UniProtKB:Q86UQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057254 name: NOXA1_HUMAN def: "NADPH oxidase activator 1" [UniProtKB:Q86UR1] synonym: "Antigen NY-CO-31" EXACT [UniProtKB:Q86UR1] synonym: "NCF2-like protein" EXACT [UniProtKB:Q86UR1] synonym: "NOX activator 1" EXACT [UniProtKB:Q86UR1] synonym: "p51-nox" EXACT [UniProtKB:Q86UR1] synonym: "P67phox-like factor" EXACT [UniProtKB:Q86UR1] xref: EMBL:AAC18046.1 xref: EMBL:AAH41594.1 xref: EMBL:AAI10841.1 xref: EMBL:AAP13480.1 xref: EMBL:AAY16126.1 xref: EMBL:AAY16127.1 xref: EMBL:BAC76710.1 xref: EMBL:CAM24776.1 xref: UniProtKB:O60533 xref: UniProtKB:Q29VU9 xref: UniProtKB:Q29VV0 xref: UniProtKB:Q2TAM1 xref: UniProtKB:Q86UR1 xref: UniProtKB:Q8IUS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018824 ! NOXA1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003064 ! superoxide-generating NADPH oxidase activator activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0007332 ! Rac GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001708 ! NADPH oxidase complex relationship: participates_in CCO:P0000922 ! regulation of hydrogen peroxide metabolic process relationship: transforms_into CCO:B0068806 ! NOXA1_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0068807 ! NOXA1_HUMAN-Phosphoserine461 [Term] id: CCO:B0057255 name: EST1A_HUMAN def: "Telomerase-binding protein EST1A" [UniProtKB:Q86US8] synonym: "EC 3.1.-.-" EXACT [UniProtKB:Q86US8] synonym: "EST1-like protein A" EXACT [UniProtKB:Q86US8] synonym: "Ever shorter telomeres 1A" EXACT [UniProtKB:Q86US8] synonym: "hSmg5/7a" EXACT [UniProtKB:Q86US8] synonym: "Smg-6 homolog" EXACT [UniProtKB:Q86US8] synonym: "Telomerase subunit EST1A" EXACT [UniProtKB:Q86US8] xref: EMBL:AAH64916.1 xref: EMBL:AAN46114.1 xref: EMBL:AAO17581.1 xref: EMBL:BAA34452.2 xref: EMBL:CAB63733.1 xref: UniProtKB:O94837 xref: UniProtKB:Q86US8 xref: UniProtKB:Q86VH6 xref: UniProtKB:Q9UF60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017731 ! SMG6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000297 ! telomerase holoenzyme complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002016 ! regulation of dephosphorylation [Term] id: CCO:B0057256 name: BCL9L_HUMAN def: "B-cell CLL/lymphoma 9-like protein" [UniProtKB:Q86UU0] synonym: "B-cell lymphoma 9-like protein" EXACT [UniProtKB:Q86UU0] synonym: "BCL9-like protein" EXACT [UniProtKB:Q86UU0] synonym: "Protein BCL9-2" EXACT [UniProtKB:Q86UU0] xref: EMBL:AAH33257.1 xref: EMBL:AAQ62697.1 xref: EMBL:BAC76045.1 xref: EMBL:BAC85500.1 xref: EMBL:BAC85512.1 xref: EMBL:EAW67418.1 xref: UniProtKB:A1A4C1 xref: UniProtKB:Q67FY1 xref: UniProtKB:Q6ZWJ0 xref: UniProtKB:Q6ZWK2 xref: UniProtKB:Q86UU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017139 ! BCL9L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063796 ! BCL9L_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0063797 ! BCL9L_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0063798 ! BCL9L_HUMAN-N6-acetyllysine36 relationship: transforms_into CCO:B0063799 ! BCL9L_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0063800 ! BCL9L_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0063801 ! BCL9L_HUMAN-Phosphoserine750 relationship: transforms_into CCO:B0063802 ! BCL9L_HUMAN-Phosphoserine813 relationship: transforms_into CCO:B0063803 ! BCL9L_HUMAN-Phosphoserine915 relationship: transforms_into CCO:B0063804 ! BCL9L_HUMAN-Phosphoserine954 relationship: transforms_into CCO:B0063805 ! BCL9L_HUMAN-Phosphothreonine957 relationship: transforms_into CCO:B0063806 ! BCL9L_HUMAN-Phosphoserine987 relationship: transforms_into CCO:B0063807 ! BCL9L_HUMAN-Phosphoserine991 relationship: transforms_into CCO:B0063808 ! BCL9L_HUMAN-Phosphoserine997 relationship: transforms_into CCO:B0063809 ! BCL9L_HUMAN-Phosphoserine999 relationship: transforms_into CCO:B0063810 ! BCL9L_HUMAN-Phosphoserine1004 relationship: transforms_into CCO:B0063811 ! BCL9L_HUMAN-Phosphoserine1010 relationship: transforms_into CCO:B0063812 ! BCL9L_HUMAN-Phosphoserine1017 [Term] id: CCO:B0057257 name: DTX2_HUMAN def: "Protein deltex-2" [UniProtKB:Q86UW9] synonym: "Deltex2" EXACT [UniProtKB:Q86UW9] synonym: "hDTX2" EXACT [UniProtKB:Q86UW9] synonym: "RING finger protein 58" EXACT [UniProtKB:Q86UW9] xref: EMBL:AAH08856.1 xref: EMBL:AAH18555.1 xref: EMBL:AAH26059.1 xref: EMBL:AAP21881.1 xref: EMBL:BAA96052.1 xref: EMBL:BAB14727.1 xref: UniProtKB:Q86UW9 xref: UniProtKB:Q96H69 xref: UniProtKB:Q9H890 xref: UniProtKB:Q9P200 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017626 ! DTX2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0014967 ! dtx2-rbpms physical interaction relationship: participates_in CCO:I0014988 ! dtx2-vsnl1 physical interaction relationship: participates_in CCO:I0015005 ! dtx2-plscr1 physical interaction relationship: participates_in CCO:I0015131 ! dtx2-pepp2 physical interaction relationship: participates_in CCO:I0015142 ! dtx2-hpcal4 physical interaction relationship: participates_in CCO:I0015299 ! dtx2-freq physical interaction relationship: participates_in CCO:I0015311 ! dtx2-rfxdc1 physical interaction relationship: participates_in CCO:I0015460 ! dtx2-ube2d4 physical interaction relationship: participates_in CCO:I0015480 ! dtx2-hpcal1 physical interaction relationship: participates_in CCO:I0015508 ! dtx2-ncald physical interaction relationship: participates_in CCO:I0017527 ! dtx2-ubqln4 physical interaction relationship: participates_in CCO:I0017595 ! ubqln4-dtx2-1 physical interaction relationship: participates_in CCO:I0019420 ! ube2d4-dtx2 physical interaction relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: transforms_into CCO:B0064902 ! DTX2_HUMAN-Phosphoserine360 [Term] id: CCO:B0057258 name: Q86UY3_HUMAN def: "ARHGAP4 protein" [UniProtKB:Q86UY3] synonym: "Rho GTPase activating protein 4, isoform CRA_b" EXACT [UniProtKB:Q86UY3] xref: EMBL:AAH52303.1 xref: EMBL:EAW72778.1 xref: UniProtKB:Q86UY3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019715 ! ARHGAP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057259 name: ZBT46_HUMAN def: "Zinc finger and BTB domain-containing protein 46" [UniProtKB:Q86UZ6] synonym: "BTB/POZ domain-containing protein 4" EXACT [UniProtKB:Q86UZ6] synonym: "Zinc finger protein 340" EXACT [UniProtKB:Q86UZ6] xref: EMBL:AAH52269.1 xref: EMBL:AAH73800.1 xref: EMBL:CAI21885.1 xref: UniProtKB:Q5JWJ3 xref: UniProtKB:Q6GMV4 xref: UniProtKB:Q86UZ6 xref: UniProtKB:Q9BQK3 xref: UniProtKB:Q9H3Z8 xref: UniProtKB:Q9H3Z9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020561 ! ZBTB46_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057260 name: CASZ1_HUMAN def: "Zinc finger protein castor homolog 1" [UniProtKB:Q86V15] synonym: "Castor-related protein" EXACT [UniProtKB:Q86V15] synonym: "Zinc finger protein 693" EXACT [UniProtKB:Q86V15] xref: EMBL:AAH04410.2 xref: EMBL:AAH51883.2 xref: EMBL:ABB29845.1 xref: EMBL:BAA91089.1 xref: EMBL:CAI22571.1 xref: UniProtKB:Q078S9 xref: UniProtKB:Q5T9S1 xref: UniProtKB:Q86V15 xref: UniProtKB:Q8WX49 xref: UniProtKB:Q8WX50 xref: UniProtKB:Q9BT16 xref: UniProtKB:Q9NXC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017242 ! CASZ1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057261 name: ZN410_HUMAN def: "Zinc finger protein 410" [UniProtKB:Q86VK4] synonym: "Another partner for ARF 1" EXACT [UniProtKB:Q86VK4] synonym: "Zinc finger protein APA-1" EXACT [UniProtKB:Q86VK4] xref: EMBL:AAB51059.1 xref: EMBL:AAH04357.1 xref: EMBL:AAH50683.1 xref: UniProtKB:O00153 xref: UniProtKB:Q86VK4 xref: UniProtKB:Q9BQ19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020736 ! ZNF410_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057262 name: Q86VL0_HUMAN def: "TCEA2 protein" [UniProtKB:Q86VL0] synonym: "Transcription elongation factor A (SII), 2, isoform CRA_b" EXACT [UniProtKB:Q86VL0] xref: EMBL:AAH50623.1 xref: EMBL:EAW75169.1 xref: UniProtKB:Q86VL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005748 ! TCEA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0057263 name: Q86VM2_HUMAN def: "Transcription factor 12 (Transcription factor 12 (HTF4, helix-loop-helix transcription factors 4), isoform CRA_b) (Helix-loop-helix transcription factor 4 isoform c)" [UniProtKB:Q86VM2] xref: EMBL:AAH50556.1 xref: EMBL:DAA01129.1 xref: EMBL:EAW77512.1 xref: UniProtKB:Q86VM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018169 ! TCF12_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057264 name: Q86VM8_HUMAN def: "TBC1D7 protein" [UniProtKB:Q86VM8] synonym: "Cell migration-inducing protein 23" EXACT [UniProtKB:Q86VM8] synonym: "TBC1 domain family, member 7, isoform CRA_a" EXACT [UniProtKB:Q86VM8] xref: EMBL:AAH50465.1 xref: EMBL:AAX18640.1 xref: EMBL:EAW55323.1 xref: UniProtKB:Q86VM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020182 ! TBC1D7_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057265 name: VPS36_HUMAN def: "Vacuolar protein-sorting-associated protein 36" [UniProtKB:Q86VN1] synonym: "ELL-associated protein of 45 kDa" EXACT [UniProtKB:Q86VN1] xref: EMBL:AAD34140.1 xref: EMBL:AAH37279.1 xref: EMBL:AAH50439.1 xref: EMBL:BAB14451.1 xref: EMBL:CAH71658.1 xref: EMBL:CAI45953.1 xref: UniProtKB:Q3ZCV7 xref: UniProtKB:Q5H9S1 xref: UniProtKB:Q5VXB6 xref: UniProtKB:Q86VN1 xref: UniProtKB:Q9H8Z5 xref: UniProtKB:Q9Y3E3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020463 ! VPS36_human relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000353 ! late endosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057266 name: TAXB1_HUMAN def: "Tax1-binding protein 1" [UniProtKB:Q86VP1] synonym: "TRAF6-binding protein" EXACT [UniProtKB:Q86VP1] xref: EMBL:AAA75595.2 xref: EMBL:AAC13359.2 xref: EMBL:AAD15412.1 xref: EMBL:AAF24016.1 xref: EMBL:AAG03025.1 xref: EMBL:AAH50358.1 xref: EMBL:CAB66521.1 xref: EMBL:CAG33337.1 xref: EMBL:CAG38587.1 xref: UniProtKB:O60398 xref: UniProtKB:O95770 xref: UniProtKB:Q13311 xref: UniProtKB:Q86VP1 xref: UniProtKB:Q9BQG5 xref: UniProtKB:Q9UI88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020152 ! TAX1BP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0057267 name: GEFT_HUMAN def: "Guanine nucleotide exchange factor GEFT" [UniProtKB:Q86VW2] synonym: "p63RhoGEF" EXACT [UniProtKB:Q86VW2] synonym: "Rac/Cdc42/Rho exchange factor GEFT" EXACT [UniProtKB:Q86VW2] synonym: "RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT" EXACT [UniProtKB:Q86VW2] xref: EMBL:AAH12860.1 xref: EMBL:AAH18536.1 xref: EMBL:AAH47559.1 xref: EMBL:AAO49463.2 xref: EMBL:EAW97037.1 xref: UniProtKB:A6NJH5 xref: UniProtKB:Q86VW2 xref: UniProtKB:Q8WV84 xref: UniProtKB:Q96E63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017914 ! GEFT_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057268 name: COMD7_HUMAN def: "COMM domain-containing protein 7" [UniProtKB:Q86VX2] xref: EMBL:AAH00628.3 xref: EMBL:AAH47440.1 xref: EMBL:AAS22244.1 xref: EMBL:BAB55436.1 xref: EMBL:CAI19095.2 xref: EMBL:CAI95302.2 xref: EMBL:CAM28357.1 xref: UniProtKB:A2BHJ2 xref: UniProtKB:Q5JYB0 xref: UniProtKB:Q86VX2 xref: UniProtKB:Q96SI7 xref: UniProtKB:Q9BW53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017435 ! COMMD7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001541 ! negative regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0001810 ! tumor necrosis factor-mediated signaling pathway [Term] id: CCO:B0057269 name: JAZF1_HUMAN def: "Juxtaposed with another zinc finger protein 1" [UniProtKB:Q86VZ6] synonym: "TAK1-interacting protein 27" EXACT [UniProtKB:Q86VZ6] synonym: "Zinc finger protein 802" EXACT [UniProtKB:Q86VZ6] xref: EMBL:AAH42441.1 xref: EMBL:AAQ74874.1 xref: EMBL:CAD38912.1 xref: UniProtKB:Q86VZ6 xref: UniProtKB:Q8N3L7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018357 ! JAZF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057270 name: Q86W07_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:Q86W07] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q86W07] xref: EMBL:AAO89505.1 xref: UniProtKB:Q86W07 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0057271 name: Z397O_HUMAN def: "Zinc finger protein 397OS" [UniProtKB:Q86W11] synonym: "Zinc finger protein 397 opposite strand" EXACT [UniProtKB:Q86W11] synonym: "ZNF-WYM" EXACT [UniProtKB:Q86W11] xref: EMBL:AAL26786.1 xref: EMBL:AAO89074.1 xref: EMBL:BAD18462.1 xref: UniProtKB:Q6ZNB3 xref: UniProtKB:Q86W11 xref: UniProtKB:Q96PN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020527 ! ZNF397OS_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057272 name: Q86W13_HUMAN def: "A1 splice variant" [UniProtKB:Q86W13] xref: EMBL:AAO89009.1 xref: UniProtKB:Q86W13 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0057273 name: KCMB4_HUMAN def: "Calcium-activated potassium channel subunit beta-4" [UniProtKB:Q86W47] synonym: "BK channel subunit beta-4" EXACT [UniProtKB:Q86W47] synonym: "BKbeta4" EXACT [UniProtKB:Q86W47] synonym: "Calcium-activated potassium channel, subfamily M subunit beta-4" EXACT [UniProtKB:Q86W47] synonym: "Charybdotoxin receptor subunit beta-4" EXACT [UniProtKB:Q86W47] synonym: "Hbeta4" EXACT [UniProtKB:Q86W47] synonym: "K(VCA)beta-4" EXACT [UniProtKB:Q86W47] synonym: "Maxi K channel subunit beta-4" EXACT [UniProtKB:Q86W47] synonym: "Slo-beta-4" EXACT [UniProtKB:Q86W47] xref: EMBL:AAF28333.1 xref: EMBL:AAF69805.1 xref: EMBL:AAF75596.1 xref: EMBL:AAF89699.1 xref: EMBL:AAH42446.2 xref: EMBL:AAH50621.2 xref: UniProtKB:Q86W47 xref: UniProtKB:Q8IVR3 xref: UniProtKB:Q9NPA4 xref: UniProtKB:Q9P0G5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018389 ! KCNMB4_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002726 ! calcium-activated potassium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002749 ! regulation of neurotransmitter secretion [Term] id: CCO:B0057274 name: Q86WD1_HUMAN def: "CREB3L2-PPARgamma" [UniProtKB:Q86WD1] xref: EMBL:AAO66458.1 xref: UniProtKB:Q86WD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057275 name: AMGO1_HUMAN def: "Amphoterin-induced protein 1 precursor" [UniProtKB:Q86WK6] synonym: "Alivin-2" EXACT [UniProtKB:Q86WK6] synonym: "AMIGO-1" EXACT [UniProtKB:Q86WK6] xref: EMBL:AAH40879.1 xref: EMBL:AAO48948.1 xref: EMBL:BAA86477.1 xref: EMBL:CAI22942.1 xref: UniProtKB:Q86WK6 xref: UniProtKB:Q8IW71 xref: UniProtKB:Q9ULQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016959 ! AMIGO1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002950 ! positive regulation of axonogenesis relationship: transforms_into CCO:B0065616 ! AMGO1_HUMAN-Phosphoserine477 [Term] id: CCO:B0057276 name: Q86WM5_HUMAN def: "Zinc finger protein LOC163141" [UniProtKB:Q86WM5] xref: EMBL:AAO45834.1 xref: UniProtKB:Q86WM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020732 ! ZNF404_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057277 name: Q86WM6_HUMAN xref: UniProtKB:Q86WM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057278 name: GPBP1_HUMAN def: "Vasculin" [UniProtKB:Q86WP2] synonym: "GC-rich promoter-binding protein 1" EXACT [UniProtKB:Q86WP2] synonym: "Vascular wall-linked protein" EXACT [UniProtKB:Q86WP2] xref: EMBL:AAH00267.1 xref: EMBL:AAH70132.1 xref: EMBL:AAI13005.1 xref: EMBL:AAO34124.1 xref: EMBL:BAB15013.1 xref: EMBL:CAB66778.1 xref: EMBL:CAB82324.2 xref: EMBL:EAW54965.1 xref: EMBL:EAW54966.1 xref: UniProtKB:A6NKW3 xref: UniProtKB:Q6NSH6 xref: UniProtKB:Q86WP2 xref: UniProtKB:Q9H0D4 xref: UniProtKB:Q9H785 xref: UniProtKB:Q9NSN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017994 ! GPBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057279 name: Q86WQ9_HUMAN def: "POLM protein" [UniProtKB:Q86WQ9] synonym: "Polymerase (DNA directed), mu, isoform CRA_f" EXACT [UniProtKB:Q86WQ9] xref: EMBL:AAH49202.2 xref: EMBL:EAW61126.1 xref: UniProtKB:Q86WQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017610 ! POLM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000416 ! DNA nucleotidylexotransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0057280 name: Q86WR9_HUMAN xref: UniProtKB:Q86WR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057281 name: SKAP1_HUMAN def: "Src kinase-associated phosphoprotein 1" [UniProtKB:Q86WV1] synonym: "pp55" EXACT [UniProtKB:Q86WV1] synonym: "SKAP-55" EXACT [UniProtKB:Q86WV1] synonym: "Src family-associated phosphoprotein 1" EXACT [UniProtKB:Q86WV1] synonym: "Src kinase-associated phosphoprotein of 55 kDa" EXACT [UniProtKB:Q86WV1] xref: EMBL:AAH47870.1 xref: EMBL:CAA72101.1 xref: UniProtKB:O15268 xref: UniProtKB:Q86WV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019926 ! SKAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070565 ! SKAP1_HUMAN-Phosphotyrosine142 relationship: transforms_into CCO:B0070566 ! SKAP1_HUMAN-Phosphotyrosine219 relationship: transforms_into CCO:B0070567 ! SKAP1_HUMAN-Phosphotyrosine232 relationship: transforms_into CCO:B0070568 ! SKAP1_HUMAN-Phosphotyrosine271 relationship: transforms_into CCO:B0070569 ! SKAP1_HUMAN-Phosphotyrosine295 [Term] id: CCO:B0057282 name: ZN227_HUMAN def: "Zinc finger protein 227" [UniProtKB:Q86WZ6] xref: EMBL:AAH47570.1 xref: UniProtKB:Q86WZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020667 ! ZNF227_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057283 name: K1219_HUMAN def: "Protein KIAA1219" [UniProtKB:Q86X10] xref: EMBL:AAH10916.2 xref: EMBL:AAH18668.1 xref: EMBL:AAH47482.1 xref: EMBL:BAA86533.3 xref: EMBL:BAC85649.1 xref: EMBL:CAB61346.1 xref: EMBL:CAD39096.1 xref: EMBL:CAM27455.1 xref: EMBL:CAM28344.1 xref: UniProtKB:A2A2E8 xref: UniProtKB:Q5TG31 xref: UniProtKB:Q86X10 xref: UniProtKB:Q8N3D1 xref: UniProtKB:Q8WWC0 xref: UniProtKB:Q9H3X8 xref: UniProtKB:Q9UJR1 xref: UniProtKB:Q9ULK1 xref: UniProtKB:Q9Y3G9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018370 ! KIAA1219_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0067232 ! K1219_HUMAN-Phosphoserine417 relationship: transforms_into CCO:B0067233 ! K1219_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0067234 ! K1219_HUMAN-Phosphoserine720 [Term] id: CCO:B0057284 name: CARM1_HUMAN def: "Histone-arginine methyltransferase CARM1" [UniProtKB:Q86X55] synonym: "Coactivator-associated arginine methyltransferase 1" EXACT [UniProtKB:Q86X55] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q86X55] synonym: "EC 2.1.1.125" EXACT [UniProtKB:Q86X55] synonym: "Protein arginine N-methyltransferase 4" EXACT [UniProtKB:Q86X55] xref: EMBL:AAH46240.1 xref: UniProtKB:Q86X55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017233 ! CARM1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001813 ! protein methyltransferase activity relationship: has_function CCO:F0001930 ! histone-arginine N-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057285 name: Q86X57_HUMAN def: "Zinc finger protein 26" [UniProtKB:Q86X57] synonym: "Zinc finger protein 26 (KOX 20), isoform CRA_a" EXACT [UniProtKB:Q86X57] xref: EMBL:AAH46206.1 xref: EMBL:EAW54803.1 xref: UniProtKB:Q86X57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021227 ! ZNF26_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057286 name: CIR_HUMAN def: "CBF1-interacting corepressor" [UniProtKB:Q86X95] synonym: "Recepin" EXACT [UniProtKB:Q86X95] xref: EMBL:AAA17853.1 xref: EMBL:AAD05243.1 xref: EMBL:AAH15040.1 xref: EMBL:AAH21175.1 xref: EMBL:AAH38987.1 xref: EMBL:AAH46098.1 xref: EMBL:AAY24216.1 xref: UniProtKB:A6NFI6 xref: UniProtKB:O95367 xref: UniProtKB:Q12804 xref: UniProtKB:Q4G1B9 xref: UniProtKB:Q6PJI4 xref: UniProtKB:Q86X95 xref: UniProtKB:Q8IWI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017368 ! CIR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016281 ! cir-sfrs2-1 physical interaction relationship: participates_in CCO:I0016282 ! cir-u2af1-1 physical interaction relationship: participates_in CCO:I0016283 ! cir-sfrs1-1 physical interaction relationship: participates_in CCO:I0016284 ! cir-rbpsuh-1 physical interaction relationship: participates_in CCO:I0018065 ! cir-sap30-1 physical interaction relationship: participates_in CCO:I0018321 ! cir-rbpsuh-2 colocalization relationship: participates_in CCO:I0018322 ! hdac2-cir-1 physical interaction relationship: participates_in CCO:I0018655 ! cir-u2af1-2 physical interaction relationship: participates_in CCO:I0018656 ! cir-sfrs2-2 physical interaction relationship: participates_in CCO:I0018657 ! cir-sfrs1-3 physical interaction relationship: participates_in CCO:I0018658 ! cir-sfrs2-3 physical interaction relationship: participates_in CCO:I0018659 ! cir-u2af1-3 physical interaction relationship: participates_in CCO:I0018660 ! cir-sfrs1-2 physical interaction relationship: participates_in CCO:I0018831 ! sfrs2-1700023b02rik colocalization relationship: participates_in CCO:I0018832 ! cir-u2af1-4 direct interaction relationship: participates_in CCO:I0018833 ! cir-hdac1-1 colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064360 ! CIR_HUMAN-Phosphoserine202 [Term] id: CCO:B0057287 name: ZN575_HUMAN def: "Zinc finger protein 575" [UniProtKB:Q86XF7] xref: EMBL:AAH43611.1 xref: UniProtKB:Q86XF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020832 ! ZNF575_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057288 name: Q86XI1_HUMAN def: "KCNH5 protein" [UniProtKB:Q86XI1] xref: EMBL:AAH43409.1 xref: UniProtKB:Q86XI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018394 ! KCNH5_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057289 name: Q86XJ5_HUMAN def: "JRK protein (Jerky homolog (Mouse), isoform CRA_a)" [UniProtKB:Q86XJ5] xref: EMBL:AAH43351.1 xref: EMBL:EAW82315.1 xref: UniProtKB:Q86XJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021228 ! JRK_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057290 name: Q86XJ6_HUMAN xref: UniProtKB:Q86XJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057291 name: ZN761_HUMAN def: "Zinc finger protein 761" [UniProtKB:Q86XN6] xref: EMBL:BAC67660.1 xref: EMBL:BAD18456.1 xref: UniProtKB:Q6ZNB9 xref: UniProtKB:Q86XN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020925 ! ZNF761_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057292 name: DGKH_HUMAN def: "Diacylglycerol kinase eta" [UniProtKB:Q86XP1] synonym: "DAG kinase eta" EXACT [UniProtKB:Q86XP1] synonym: "DGK-eta" EXACT [UniProtKB:Q86XP1] synonym: "Diglyceride kinase eta" EXACT [UniProtKB:Q86XP1] synonym: "EC 2.7.1.107" EXACT [UniProtKB:Q86XP1] xref: EMBL:AAH43292.1 xref: EMBL:BAC05280.1 xref: EMBL:BAC66960.1 xref: EMBL:BAC66961.1 xref: EMBL:CAD38739.1 xref: EMBL:CAH71062.2 xref: EMBL:CAH71399.2 xref: EMBL:CAI16894.2 xref: EMBL:CAM13770.1 xref: EMBL:CAM14245.1 xref: EMBL:CAM23676.1 xref: UniProtKB:A2A2W7 xref: UniProtKB:A6NFX7 xref: UniProtKB:Q5VZW0 xref: UniProtKB:Q6PI56 xref: UniProtKB:Q86XP1 xref: UniProtKB:Q86XP2 xref: UniProtKB:Q8N3N0 xref: UniProtKB:Q8N7J9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017569 ! DGKH_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057293 name: TCAM2_HUMAN def: "TIR domain-containing adapter molecule 2" [UniProtKB:Q86XR7] synonym: "Putative NF-kappa-B-activating protein 502" EXACT [UniProtKB:Q86XR7] synonym: "TICAM-2" EXACT [UniProtKB:Q86XR7] synonym: "Toll-like receptor adaptor protein 3" EXACT [UniProtKB:Q86XR7] synonym: "Toll/interleukin-1 receptor domain-containing protein" EXACT [UniProtKB:Q86XR7] synonym: "TRIF-related adapter molecule" EXACT [UniProtKB:Q86XR7] xref: EMBL:AAI09266.1 xref: EMBL:AAI09267.1 xref: EMBL:AAO74498.1 xref: EMBL:AAP81748.1 xref: EMBL:AAQ97431.1 xref: EMBL:AAQ97432.1 xref: EMBL:BAC77375.1 xref: EMBL:BAC98397.1 xref: EMBL:BAC98399.1 xref: EMBL:EAW48960.1 xref: UniProtKB:Q86XR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020209 ! TICAM2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0018039 ! il1r1-tirp physical interaction relationship: participates_in CCO:I0018040 ! il1racp-tirp-1 physical interaction relationship: participates_in CCO:I0018041 ! traf6-tirp physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0071257 ! TCAM2_HUMAN-Phosphoserine16 [Term] id: CCO:B0057294 name: CEP57_HUMAN def: "Centrosomal protein of 57 kDa" [UniProtKB:Q86XR8] synonym: "Cep57 protein" EXACT [UniProtKB:Q86XR8] synonym: "FGF2-interacting protein" EXACT [UniProtKB:Q86XR8] synonym: "Testis-specific protein 57" EXACT [UniProtKB:Q86XR8] synonym: "Translokin" EXACT [UniProtKB:Q86XR8] xref: EMBL:AAH01233.1 xref: EMBL:AAH39711.1 xref: EMBL:AAO73938.1 xref: EMBL:BAA07654.2 xref: UniProtKB:Q14704 xref: UniProtKB:Q86XR8 xref: UniProtKB:Q8IXP0 xref: UniProtKB:Q9BVF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017334 ! CEP57_human relationship: has_function CCO:F0003590 ! fibroblast growth factor binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0057295 name: ZN677_HUMAN def: "Zinc finger protein 677" [UniProtKB:Q86XU0] xref: EMBL:AAH50038.1 xref: UniProtKB:Q86XU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020892 ! ZNF677_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057296 name: Q86XV5_HUMAN def: "CENTG3 protein" [UniProtKB:Q86XV5] xref: EMBL:AAH48300.1 xref: UniProtKB:Q86XV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017332 ! CENTG3_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0057297 name: Q86XV6_HUMAN def: "Rho GTPase activating protein 8" [UniProtKB:Q86XV6] xref: EMBL:AAH48280.2 xref: UniProtKB:Q86XV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005481 ! ARHGAP8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057298 name: DTX1_HUMAN def: "Protein deltex-1" [UniProtKB:Q86Y01] synonym: "Deltex1" EXACT [UniProtKB:Q86Y01] synonym: "hDTX1" EXACT [UniProtKB:Q86Y01] xref: EMBL:AAC06246.1 xref: EMBL:AAH05816.2 xref: EMBL:AAH48216.1 xref: UniProtKB:O60630 xref: UniProtKB:Q86Y01 xref: UniProtKB:Q9BS04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017625 ! DTX1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000829 ! regulation of Notch signaling pathway relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation [Term] id: CCO:B0057299 name: Z354C_HUMAN def: "Zinc finger protein 354C" [UniProtKB:Q86Y25] synonym: "hKID3" EXACT [UniProtKB:Q86Y25] synonym: "Kidney, ischemia, and developmentally-regulated protein 3" EXACT [UniProtKB:Q86Y25] xref: EMBL:AAH63312.1 xref: EMBL:AAM69676.1 xref: EMBL:AAO83897.1 xref: UniProtKB:Q6P4P9 xref: UniProtKB:Q86Y25 xref: UniProtKB:Q8NFX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020525 ! ZNF354C_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057300 name: GPR97_HUMAN def: "Probable G-protein coupled receptor 97 precursor" [UniProtKB:Q86Y34] synonym: "G-protein coupled receptor PGR26" EXACT [UniProtKB:Q86Y34] xref: EMBL:AAH64508.1 xref: EMBL:AAN46673.1 xref: EMBL:AAO85113.1 xref: EMBL:BAC67700.1 xref: EMBL:BAD18774.1 xref: UniProtKB:Q6ZMF4 xref: UniProtKB:Q86SL9 xref: UniProtKB:Q86Y34 xref: UniProtKB:Q8IZF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018042 ! GPR97_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057301 name: STX12_HUMAN def: "Syntaxin-12" [UniProtKB:Q86Y82] xref: EMBL:AAH46999.1 xref: EMBL:AAP97248.1 xref: EMBL:CAA22911.1 xref: UniProtKB:O95564 xref: UniProtKB:Q86Y82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020077 ! STX12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002964 ! protein stabilization relationship: transforms_into CCO:B0070984 ! STX12_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0070985 ! STX12_HUMAN-Phosphoserine142 [Term] id: CCO:B0057302 name: Q86YC4_HUMAN def: "Similar to plexin A" [UniProtKB:Q86YC4] xref: EMBL:AAH44228.1 xref: UniProtKB:Q86YC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057303 name: ZN573_HUMAN def: "Zinc finger protein 573" [UniProtKB:Q86YE8] xref: EMBL:AAH15418.1 xref: EMBL:AAH42170.2 xref: EMBL:AAH51263.1 xref: EMBL:AAH64962.1 xref: EMBL:BAB70929.1 xref: EMBL:BAC11047.1 xref: UniProtKB:Q6P1P1 xref: UniProtKB:Q7Z7Q3 xref: UniProtKB:Q86YE8 xref: UniProtKB:Q8N2Q1 xref: UniProtKB:Q96BM3 xref: UniProtKB:Q96NH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020830 ! ZNF573_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057304 name: Z280B_HUMAN def: "Zinc finger protein 280B" [UniProtKB:Q86YH2] synonym: "5'OY11.1" EXACT [UniProtKB:Q86YH2] synonym: "Suppressor of hairy wing homolog 2" EXACT [UniProtKB:Q86YH2] synonym: "Zinc finger protein 279" EXACT [UniProtKB:Q86YH2] synonym: "Zinc finger protein 632" EXACT [UniProtKB:Q86YH2] xref: EMBL:AAH40020.1 xref: EMBL:BAA20005.1 xref: EMBL:CAG30500.1 xref: UniProtKB:Q86YH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020515 ! ZNF280B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071931 ! Z280B_HUMAN-Phosphoserine105 [Term] id: CCO:B0057305 name: Q86YJ0_HUMAN def: "RCAN2 protein" [UniProtKB:Q86YJ0] xref: EMBL:AAH38509.1 xref: UniProtKB:Q86YJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019654 ! RCAN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:B0057306 name: PDPN_HUMAN def: "Podoplanin precursor" [UniProtKB:Q86YL7] synonym: "Aggrus" EXACT [UniProtKB:Q86YL7] synonym: "Glycoprotein 36" EXACT [UniProtKB:Q86YL7] synonym: "Gp36" EXACT [UniProtKB:Q86YL7] synonym: "PA2.26 antigen" EXACT [UniProtKB:Q86YL7] synonym: "T1-alpha" EXACT [UniProtKB:Q86YL7] synonym: "T1A" EXACT [UniProtKB:Q86YL7] xref: EMBL:AAD01899.1 xref: EMBL:AAD01900.1 xref: EMBL:AAH14668.2 xref: EMBL:AAH22812.2 xref: EMBL:AAM73655.1 xref: EMBL:AAO22143.1 xref: EMBL:BAC11550.1 xref: EMBL:BAC11557.1 xref: EMBL:BAD04046.1 xref: EMBL:CAA12352.1 xref: EMBL:CAI17984.1 xref: EMBL:CAI21929.1 xref: UniProtKB:O60836 xref: UniProtKB:O95128 xref: UniProtKB:Q7L375 xref: UniProtKB:Q86YL7 xref: UniProtKB:Q8NBQ8 xref: UniProtKB:Q8NBR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019350 ! PDPN_human relationship: has_function CCO:F0001597 ! water transporter activity relationship: has_function CCO:F0001970 ! folic acid transporter activity relationship: has_function CCO:F0002648 ! amino acid transmembrane transporter activity relationship: has_function CCO:F0002717 ! water channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000989 ! filopodium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0003073 ! positive regulation of cell motility [Term] id: CCO:B0057307 name: HOME1_HUMAN def: "Homer protein homolog 1" [UniProtKB:Q86YM7] xref: EMBL:AAC71026.1 xref: EMBL:AAH15502.1 xref: EMBL:AAO38999.1 xref: EMBL:AAO39001.1 xref: EMBL:AAP88848.1 xref: EMBL:CAA76877.1 xref: UniProtKB:O96003 xref: UniProtKB:Q86YM5 xref: UniProtKB:Q86YM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018152 ! HOMER1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0015283 ! abi3-homer1 physical interaction relationship: participates_in CCO:I0015701 ! c1orf116-homer1 physical interaction relationship: participates_in CCO:P0000741 ! metabotropic glutamate receptor, phospholipase C activating pathway [Term] id: CCO:B0057308 name: PRGC2_HUMAN def: "Peroxisome proliferator-activated receptor gamma coactivator 1-beta" [UniProtKB:Q86YN6] synonym: "PGC-1-beta" EXACT [UniProtKB:Q86YN6] synonym: "PGC-1-related estrogen receptor alpha coactivator" EXACT [UniProtKB:Q86YN6] synonym: "PPAR-gamma coactivator 1-beta" EXACT [UniProtKB:Q86YN6] synonym: "PPARGC-1-beta" EXACT [UniProtKB:Q86YN6] xref: EMBL:AAL78633.1 xref: EMBL:AAL78634.1 xref: EMBL:AAO40022.1 xref: EMBL:AAO40023.1 xref: EMBL:AAO40024.1 xref: EMBL:AAO40025.1 xref: EMBL:BAC04541.1 xref: UniProtKB:Q86YN3 xref: UniProtKB:Q86YN4 xref: UniProtKB:Q86YN5 xref: UniProtKB:Q86YN6 xref: UniProtKB:Q8N1N9 xref: UniProtKB:Q8TDE4 xref: UniProtKB:Q8TDE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019508 ! PPARGC1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0069499 ! PRGC2_HUMAN-Phosphoserine524 [Term] id: CCO:B0057309 name: GPSM1_HUMAN def: "G-protein-signaling modulator 1" [UniProtKB:Q86YR5] synonym: "Activator of G-protein signaling 3" EXACT [UniProtKB:Q86YR5] xref: EMBL:AAH09979.1 xref: EMBL:AAH17353.1 xref: EMBL:AAH48343.1 xref: EMBL:AAO17260.1 xref: EMBL:CAB55951.1 xref: EMBL:CAM27654.1 xref: EMBL:EAW88216.1 xref: UniProtKB:A9Z1X4 xref: UniProtKB:Q86SR5 xref: UniProtKB:Q86YR5 xref: UniProtKB:Q969T1 xref: UniProtKB:Q9UFS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018044 ! GPSM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066552 ! GPSM1_HUMAN-Phosphoserine448 relationship: transforms_into CCO:B0066553 ! GPSM1_HUMAN-Phosphoserine469 relationship: transforms_into CCO:B0066554 ! GPSM1_HUMAN-Phosphoserine470 [Term] id: CCO:B0057310 name: MF2L2_HUMAN def: "Probable guanine nucleotide exchange factor MCF2L2" [UniProtKB:Q86YR7] synonym: "Dbs-related Rho family guanine nucleotide exchange factor" EXACT [UniProtKB:Q86YR7] synonym: "MCF2-transforming sequence-like protein 2" EXACT [UniProtKB:Q86YR7] xref: EMBL:AAH29074.2 xref: EMBL:AAH64632.1 xref: EMBL:AAO19651.1 xref: EMBL:BAA74884.1 xref: EMBL:BAC85866.1 xref: UniProtKB:O94942 xref: UniProtKB:Q6P2B8 xref: UniProtKB:Q6ZVJ5 xref: UniProtKB:Q86YR7 xref: UniProtKB:Q8N318 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018608 ! MCF2L2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057311 name: RAB43_HUMAN def: "Ras-related protein Rab-43" [UniProtKB:Q86YS6] synonym: "Ras-related protein Rab-41" EXACT [UniProtKB:Q86YS6] xref: EMBL:AAH62319.1 xref: EMBL:AAO17291.1 xref: UniProtKB:Q86YS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019599 ! RAB43_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069687 ! RAB43_HUMAN-Phosphoserine193 relationship: transforms_into CCO:B0069688 ! RAB43_HUMAN-Cysteine methyl ester212 [Term] id: CCO:B0057312 name: MIB1_HUMAN def: "E3 ubiquitin-protein ligase MIB1" [UniProtKB:Q86YT6] synonym: "DAPK-interacting protein 1" EXACT [UniProtKB:Q86YT6] synonym: "DIP-1" EXACT [UniProtKB:Q86YT6] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q86YT6] synonym: "Mind bomb homolog 1" EXACT [UniProtKB:Q86YT6] synonym: "Zinc finger ZZ type with ankyrin repeat domain protein 2" EXACT [UniProtKB:Q86YT6] xref: EMBL:AAH22403.1 xref: EMBL:AAI10582.1 xref: EMBL:AAI10583.1 xref: EMBL:AAN18023.1 xref: EMBL:AAN75493.1 xref: EMBL:BAA92561.1 xref: EMBL:BAC11439.1 xref: EMBL:CAD28502.1 xref: EMBL:CAH18429.1 xref: UniProtKB:Q2TB37 xref: UniProtKB:Q68D01 xref: UniProtKB:Q6YI51 xref: UniProtKB:Q86YT6 xref: UniProtKB:Q8NBY0 xref: UniProtKB:Q8TCB5 xref: UniProtKB:Q8TCL7 xref: UniProtKB:Q9P2M3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018617 ! MIB1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation relationship: participates_in CCO:P0002557 ! positive regulation of endocytosis [Term] id: CCO:B0057313 name: Q86YV2_HUMAN def: "FLJ00332 protein" [UniProtKB:Q86YV2] xref: EMBL:BAC56926.1 xref: UniProtKB:Q86YV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021229 ! FLJ00332_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057314 name: PLCZ1_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1" [UniProtKB:Q86YW0] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q86YW0] synonym: "Phospholipase C-zeta-1" EXACT [UniProtKB:Q86YW0] synonym: "PLC-zeta-1" EXACT [UniProtKB:Q86YW0] synonym: "Testis-development protein NYD-SP27" EXACT [UniProtKB:Q86YW0] xref: EMBL:AAI25068.1 xref: EMBL:AAK61372.1 xref: EMBL:AAN71895.1 xref: EMBL:BAF84968.1 xref: UniProtKB:Q08AQ7 xref: UniProtKB:Q86YW0 xref: UniProtKB:Q96J70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022519 ! PLCZ1_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057315 name: Q86YY0_HUMAN def: "NCOR isoform b" [UniProtKB:Q86YY0] xref: EMBL:AAO32942.1 xref: UniProtKB:Q86YY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057316 name: Q86YZ7_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q86YZ7] xref: EMBL:BAC55271.1 xref: UniProtKB:Q86YZ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057317 name: IL29_HUMAN def: "Interleukin-29 precursor" [UniProtKB:Q8IU54] synonym: "Cytokine ZCYTO21" EXACT [UniProtKB:Q8IU54] synonym: "IFN-lambda-1" EXACT [UniProtKB:Q8IU54] synonym: "IL-29" EXACT [UniProtKB:Q8IU54] synonym: "Interferon lambda-1" EXACT [UniProtKB:Q8IU54] xref: EMBL:AAH74985.1 xref: EMBL:AAI17483.1 xref: EMBL:AAI26184.1 xref: EMBL:AAN28265.1 xref: EMBL:AAN86125.1 xref: EMBL:AAR24511.1 xref: UniProtKB:A0AV25 xref: UniProtKB:Q17R34 xref: UniProtKB:Q8IU54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018261 ! IL29_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0004924 ! interleukin-28 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001380 ! interleukin-28 receptor complex relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002694 ! positive regulation of JAK-STAT cascade [Term] id: CCO:B0057318 name: I28RA_HUMAN def: "Interleukin-28 receptor alpha chain precursor" [UniProtKB:Q8IU57] synonym: "CRF2-12" EXACT [UniProtKB:Q8IU57] synonym: "Cytokine receptor class-II member 12" EXACT [UniProtKB:Q8IU57] synonym: "Cytokine receptor family 2 member 12" EXACT [UniProtKB:Q8IU57] synonym: "IFN-lambda R1" EXACT [UniProtKB:Q8IU57] synonym: "IL-28R-alpha" EXACT [UniProtKB:Q8IU57] synonym: "IL-28RA" EXACT [UniProtKB:Q8IU57] synonym: "Interferon lambda receptor 1" EXACT [UniProtKB:Q8IU57] synonym: "Likely interleukin or cytokine receptor 2" EXACT [UniProtKB:Q8IU57] xref: EMBL:AAN28266.1 xref: EMBL:AAN28267.1 xref: EMBL:AAN28268.1 xref: EMBL:AAN63632.1 xref: EMBL:BAD18707.1 xref: EMBL:CAD58829.1 xref: UniProtKB:Q6ZML8 xref: UniProtKB:Q8IU57 xref: UniProtKB:Q8IZI7 xref: UniProtKB:Q8IZI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018202 ! IL28RA_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001254 ! interleukin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001380 ! interleukin-28 receptor complex relationship: participates_in CCO:I0017328 ! lsm8-il28ra physical interaction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0057319 name: I2BP1_HUMAN def: "Interferon regulatory factor 2-binding protein 1" [UniProtKB:Q8IU81] synonym: "IRF-2-binding protein 1" EXACT [UniProtKB:Q8IU81] synonym: "IRF-2BP1" EXACT [UniProtKB:Q8IU81] xref: EMBL:AAH05834.2 xref: EMBL:AAH38222.1 xref: EMBL:AAH39002.1 xref: EMBL:AAH78181.1 xref: EMBL:AAP78943.1 xref: EMBL:BAD97342.1 xref: EMBL:CAB45750.1 xref: EMBL:EAW57396.1 xref: UniProtKB:Q53EL7 xref: UniProtKB:Q6DC95 xref: UniProtKB:Q8IU81 xref: UniProtKB:Q9BRZ9 xref: UniProtKB:Q9Y4P4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018203 ! IRF2BP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066968 ! I2BP1_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0066969 ! I2BP1_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0066970 ! I2BP1_HUMAN-Phosphoserine186 relationship: transforms_into CCO:B0066971 ! I2BP1_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0066972 ! I2BP1_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0066973 ! I2BP1_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0066974 ! I2BP1_HUMAN-Phosphoserine457 [Term] id: CCO:B0057320 name: RHPN2_HUMAN def: "Rhophilin-2" [UniProtKB:Q8IUC4] synonym: "76 kDa RhoB effector protein" EXACT [UniProtKB:Q8IUC4] synonym: "GTP-Rho-binding protein 2" EXACT [UniProtKB:Q8IUC4] synonym: "p76RBE" EXACT [UniProtKB:Q8IUC4] xref: EMBL:AAH36447.1 xref: EMBL:AAK58588.1 xref: EMBL:AAQ04062.1 xref: EMBL:BAC04471.1 xref: EMBL:CAC87939.1 xref: EMBL:CAD38597.1 xref: UniProtKB:Q8IUC4 xref: UniProtKB:Q8N3T7 xref: UniProtKB:Q8N9D6 xref: UniProtKB:Q8NE33 xref: UniProtKB:Q96RU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019739 ! RHPN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070015 ! RHPN2_HUMAN-Nitrated tyrosine258 relationship: transforms_into CCO:B0070016 ! RHPN2_HUMAN-Phosphoserine639 [Term] id: CCO:B0057321 name: TCAM1_HUMAN def: "TIR domain-containing adapter molecule 1" [UniProtKB:Q8IUC6] synonym: "Proline-rich, vinculin and TIR domain-containing protein B" EXACT [UniProtKB:Q8IUC6] synonym: "Putative NF-kappa-B-activating protein 502H" EXACT [UniProtKB:Q8IUC6] synonym: "TICAM-1" EXACT [UniProtKB:Q8IUC6] synonym: "TIR domain-containing adapter protein inducing IFN-beta" EXACT [UniProtKB:Q8IUC6] synonym: "Toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta" EXACT [UniProtKB:Q8IUC6] xref: EMBL:AAC28630.1 xref: EMBL:AAH09860.2 xref: EMBL:AAO85488.1 xref: EMBL:BAC44839.1 xref: EMBL:BAC55579.1 xref: EMBL:BAC77376.1 xref: UniProtKB:O75532 xref: UniProtKB:Q86XP8 xref: UniProtKB:Q8IUC6 xref: UniProtKB:Q96GA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020208 ! TICAM1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0057322 name: RB6I2_HUMAN def: "ELKS/RAB6-interacting/CAST family member 1" [UniProtKB:Q8IUD2] synonym: "ERC protein 1" EXACT [UniProtKB:Q8IUD2] synonym: "RAB6-interacting protein 2" EXACT [UniProtKB:Q8IUD2] xref: EMBL:AAH68006.1 xref: EMBL:BAA83033.2 xref: EMBL:BAA88763.1 xref: EMBL:BAA90975.1 xref: EMBL:BAC03827.1 xref: EMBL:BAC54107.1 xref: EMBL:BAC54108.1 xref: EMBL:BAC54109.1 xref: EMBL:BAC54110.1 xref: UniProtKB:Q6NVK2 xref: UniProtKB:Q8IUD2 xref: UniProtKB:Q8IUD3 xref: UniProtKB:Q8IUD4 xref: UniProtKB:Q8IUD5 xref: UniProtKB:Q8NAS1 xref: UniProtKB:Q9NXN5 xref: UniProtKB:Q9UIK7 xref: UniProtKB:Q9UPS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019644 ! ERC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000770 ! I-kappaB phosphorylation relationship: participates_in CCO:P0002545 ! positive regulation of anti-apoptosis relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: transforms_into CCO:B0069763 ! RB6I2_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0069764 ! RB6I2_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0069765 ! RB6I2_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0069766 ! RB6I2_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0069767 ! RB6I2_HUMAN-Phosphothreonine1046 [Term] id: CCO:B0057323 name: ZDH13_HUMAN def: "Probable palmitoyltransferase ZDHHC13" [UniProtKB:Q8IUH4] synonym: "DHHC-13" EXACT [UniProtKB:Q8IUH4] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q8IUH4] synonym: "HIP14-related protein" EXACT [UniProtKB:Q8IUH4] synonym: "Huntingtin-interacting protein 14-related protein" EXACT [UniProtKB:Q8IUH4] synonym: "Huntingtin-interacting protein HIP3RP" EXACT [UniProtKB:Q8IUH4] synonym: "Putative MAPK-activating protein PM03" EXACT [UniProtKB:Q8IUH4] synonym: "Putative NF-kappa-B-activating protein 209" EXACT [UniProtKB:Q8IUH4] synonym: "Zinc finger DHHC domain-containing protein 13" EXACT [UniProtKB:Q8IUH4] xref: EMBL:AAH36020.1 xref: EMBL:AAH50690.2 xref: EMBL:AAH56152.1 xref: EMBL:BAA91856.1 xref: EMBL:BAA91930.1 xref: EMBL:BAC22090.1 xref: EMBL:BAC77367.1 xref: EMBL:BAC77380.1 xref: UniProtKB:Q7Z2D3 xref: UniProtKB:Q86VK2 xref: UniProtKB:Q8IUH4 xref: UniProtKB:Q9NV30 xref: UniProtKB:Q9NV99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020574 ! ZDHHC13_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0057324 name: ZDH17_HUMAN def: "Palmitoyltransferase ZDHHC17" [UniProtKB:Q8IUH5] synonym: "DHHC-17" EXACT [UniProtKB:Q8IUH5] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q8IUH5] synonym: "Huntingtin yeast partner H" EXACT [UniProtKB:Q8IUH5] synonym: "Huntingtin-interacting protein 14" EXACT [UniProtKB:Q8IUH5] synonym: "Huntingtin-interacting protein 3" EXACT [UniProtKB:Q8IUH5] synonym: "Huntingtin-interacting protein H" EXACT [UniProtKB:Q8IUH5] synonym: "Putative MAPK-activating protein PM11" EXACT [UniProtKB:Q8IUH5] synonym: "Putative NF-kappa-B-activating protein 205" EXACT [UniProtKB:Q8IUH5] synonym: "Zinc finger DHHC domain-containing protein 17" EXACT [UniProtKB:Q8IUH5] xref: EMBL:AAC26848.1 xref: EMBL:AAF28972.1 xref: EMBL:AAH30990.1 xref: EMBL:AAH50324.1 xref: EMBL:BAA76790.1 xref: EMBL:BAC22089.1 xref: EMBL:BAC77366.1 xref: EMBL:BAC77388.1 xref: UniProtKB:O75407 xref: UniProtKB:Q7Z2I0 xref: UniProtKB:Q86W89 xref: UniProtKB:Q86YK0 xref: UniProtKB:Q8IUH5 xref: UniProtKB:Q9P088 xref: UniProtKB:Q9UPZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020575 ! ZDHHC17_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004146 ! protein-cysteine S-palmitoleyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0018035 ! hip14-snap25-1 palmitoylation relationship: participates_in CCO:I0018036 ! hip14-snap25-2 palmitoylation relationship: participates_in CCO:I0018037 ! hip14-syt1-1 palmitoylation relationship: participates_in CCO:I0018038 ! hip14-hd-2 palmitoylation relationship: participates_in CCO:I0018494 ! hip14-snap25-3 colocalization relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0071986 ! ZDH17_HUMAN-Phosphotyrosine70 [Term] id: CCO:B0057325 name: NPAS4_HUMAN def: "Neuronal PAS domain-containing protein 4" [UniProtKB:Q8IUM7] synonym: "HLH-PAS transcription factor NXF" EXACT [UniProtKB:Q8IUM7] synonym: "Neuronal PAS4" EXACT [UniProtKB:Q8IUM7] xref: EMBL:AAI05002.1 xref: EMBL:AAI05004.1 xref: EMBL:BAC04271.1 xref: EMBL:BAC04738.1 xref: EMBL:BAC19830.1 xref: UniProtKB:Q8IUM7 xref: UniProtKB:Q8N8S5 xref: UniProtKB:Q8N9Q9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018829 ! NPAS4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057326 name: Q8IUP5_HUMAN def: "CASP10 protein" [UniProtKB:Q8IUP5] synonym: "Caspase 10, apoptosis-related cysteine peptidase" EXACT [UniProtKB:Q8IUP5] synonym: "Caspase 10, apoptosis-related cysteine peptidase, isoform CRA_c" EXACT [UniProtKB:Q8IUP5] synonym: "Putative uncharacterized protein CASP10" EXACT [UniProtKB:Q8IUP5] xref: EMBL:AAH42844.1 xref: EMBL:AAY24291.1 xref: EMBL:ABJ53426.1 xref: EMBL:EAW70249.1 xref: UniProtKB:Q8IUP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017240 ! CASP10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0057327 name: Q8IUT4_HUMAN xref: UniProtKB:Q8IUT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057328 name: Q8IUU5_HUMAN def: "RASGRF1 protein" [UniProtKB:Q8IUU5] synonym: "Ras protein-specific guanine nucleotide-releasing factor 1, isoform CRA_b" EXACT [UniProtKB:Q8IUU5] xref: EMBL:AAH40275.1 xref: EMBL:EAW99142.1 xref: UniProtKB:Q8IUU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019699 ! RASGRF1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057329 name: Q8IUX2_HUMAN def: "Microtubule-associated protein" [UniProtKB:Q8IUX2] xref: EMBL:AAH38857.1 xref: UniProtKB:Q8IUX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0014816 ! MAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization [Term] id: CCO:B0057330 name: AEBP1_HUMAN def: "Adipocyte enhancer-binding protein 1 precursor" [UniProtKB:Q8IUX7] synonym: "AE-binding protein 1" EXACT [UniProtKB:Q8IUX7] synonym: "Aortic carboxypeptidase-like protein" EXACT [UniProtKB:Q8IUX7] xref: EMBL:AAC25585.1 xref: EMBL:AAH38588.1 xref: EMBL:BAA13094.1 xref: EMBL:BAC87026.1 xref: EMBL:BAD92981.1 xref: EMBL:EAL23768.1 xref: EMBL:EAW61119.1 xref: UniProtKB:Q14113 xref: UniProtKB:Q59ER7 xref: UniProtKB:Q6ZSC7 xref: UniProtKB:Q7KZ79 xref: UniProtKB:Q8IUX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016926 ! AEBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000649 ! carboxypeptidase activity relationship: has_function CCO:F0000651 ! carboxypeptidase A activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057331 name: Q8IUY2_HUMAN xref: UniProtKB:Q8IUY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057332 name: TB10C_HUMAN def: "Carabin" [UniProtKB:Q8IV04] synonym: "TBC1 domain family member 10C" EXACT [UniProtKB:Q8IV04] xref: EMBL:AAH36873.3 xref: EMBL:AAH62999.1 xref: UniProtKB:Q8IV04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020155 ! TBC1D10C_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057333 name: Q8IV15_HUMAN def: "Potassium voltage-gated channel, subfamily H (Eag-related), member 7" [UniProtKB:Q8IV15] xref: EMBL:AAH35815.1 xref: UniProtKB:Q8IV15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018396 ! KCNH7_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057334 name: PSTK_HUMAN def: "L-seryl-tRNA(Sec) kinase" [UniProtKB:Q8IV42] synonym: "EC 2.7.1.n3" EXACT [UniProtKB:Q8IV42] synonym: "O-phosphoseryl-tRNA(Sec) kinase" EXACT [UniProtKB:Q8IV42] xref: EMBL:AAH35344.1 xref: EMBL:BAC86867.1 xref: UniProtKB:Q6ZSS9 xref: UniProtKB:Q8IV42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019534 ! PSTK_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000465 ! selenocysteine incorporation [Term] id: CCO:B0057335 name: UN5CL_HUMAN def: "UNC5C-like protein" [UniProtKB:Q8IV45] synonym: "Protein unc-5 homolog C-like" EXACT [UniProtKB:Q8IV45] synonym: "ZU5 and death domain-containing protein" EXACT [UniProtKB:Q8IV45] xref: EMBL:AAH35284.1 xref: EMBL:AAS80165.1 xref: EMBL:CAI20283.1 xref: EMBL:EAX04007.1 xref: UniProtKB:Q5TGU1 xref: UniProtKB:Q8IV45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020410 ! UNC5CL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057336 name: THEX1_HUMAN def: "Histone mRNA 3'-exonuclease 1" [UniProtKB:Q8IV48] synonym: "3'-5' exonuclease ERI1" EXACT [UniProtKB:Q8IV48] synonym: "EC 3.1.-.-" EXACT [UniProtKB:Q8IV48] synonym: "Eri-1 homolog" EXACT [UniProtKB:Q8IV48] synonym: "HEXO" EXACT [UniProtKB:Q8IV48] synonym: "Histone mRNA 3'-end-specific exoribonuclease" EXACT [UniProtKB:Q8IV48] synonym: "Protein 3'hExo" EXACT [UniProtKB:Q8IV48] xref: EMBL:AAH35279.1 xref: EMBL:AAQ21219.1 xref: EMBL:CAB70871.2 xref: UniProtKB:Q8IV48 xref: UniProtKB:Q9NSX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020254 ! THEX1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:B0057337 name: GRP3_HUMAN def: "Ras guanyl-releasing protein 3" [UniProtKB:Q8IV61] synonym: "Calcium and DAG-regulated guanine nucleotide exchange factor III" EXACT [UniProtKB:Q8IV61] synonym: "Guanine nucleotide exchange factor for Rap1" EXACT [UniProtKB:Q8IV61] xref: EMBL:AAH27849.1 xref: EMBL:BAA74869.2 xref: UniProtKB:O94931 xref: UniProtKB:Q8IV61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018077 ! RASGRP3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003512 ! Ras GTPase binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006230 ! Rap GTPase activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057338 name: Q8IV68_HUMAN def: "LOC442421 protein" [UniProtKB:Q8IV68] xref: EMBL:AAH42539.1 xref: UniProtKB:Q8IV68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021030 ! LOC442421_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001299 ! prostaglandin E receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057339 name: Q8IV75_HUMAN xref: UniProtKB:Q8IV75 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057340 name: WASF4_HUMAN def: "Wiskott-Aldrich syndrome protein family member 4" [UniProtKB:Q8IV90] synonym: "WASP family protein member 4" EXACT [UniProtKB:Q8IV90] xref: EMBL:AAD33053.2 xref: EMBL:CAD48858.1 xref: UniProtKB:Q8IV90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020470 ! WASF4_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057341 name: PCP2_HUMAN def: "Purkinje cell protein 2 homolog" [UniProtKB:Q8IVA1] xref: EMBL:AAH25387.1 xref: EMBL:AAH38715.2 xref: UniProtKB:Q3KRG7 xref: UniProtKB:Q8IVA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019322 ! PCP2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057342 name: ZN584_HUMAN def: "Zinc finger protein 584" [UniProtKB:Q8IVC4] xref: EMBL:AAH33149.1 xref: UniProtKB:Q8IVC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020838 ! ZNF584_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057343 name: TIAM2_HUMAN def: "T-lymphoma invasion and metastasis-inducing protein 2" [UniProtKB:Q8IVF5] synonym: "SIF and TIAM1-like exchange factor" EXACT [UniProtKB:Q8IVF5] synonym: "TIAM-2" EXACT [UniProtKB:Q8IVF5] xref: EMBL:AAF05900.1 xref: EMBL:AAF05901.1 xref: EMBL:AAH66979.1 xref: EMBL:BAC23112.2 xref: EMBL:BAC86170.1 xref: EMBL:CAB59259.2 xref: EMBL:EAW47693.1 xref: UniProtKB:Q6NXN9 xref: UniProtKB:Q6ZUP9 xref: UniProtKB:Q8IVF5 xref: UniProtKB:Q9UFG6 xref: UniProtKB:Q9UKV9 xref: UniProtKB:Q9UKW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020261 ! TIAM2_human relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0071398 ! TIAM2_HUMAN-Phosphothreonine1648 [Term] id: CCO:B0057344 name: HUNIN_HUMAN def: "Humanin" [UniProtKB:Q8IVG9] xref: EMBL:AAK50430.1 xref: UniProtKB:Q8IVG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018173 ! HN_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007301 ! receptor antagonist activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0057345 name: M4K3_HUMAN def: "Mitogen-activated protein kinase kinase kinase kinase 3" [UniProtKB:Q8IVH8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8IVH8] synonym: "Germinal center kinase-related protein kinase" EXACT [UniProtKB:Q8IVH8] synonym: "GLK" EXACT [UniProtKB:Q8IVH8] synonym: "MAPK/ERK kinase kinase kinase 3" EXACT [UniProtKB:Q8IVH8] synonym: "MEK kinase kinase 3" EXACT [UniProtKB:Q8IVH8] synonym: "MEKKK 3" EXACT [UniProtKB:Q8IVH8] xref: EMBL:AAC15472.1 xref: EMBL:AAF19240.1 xref: EMBL:AAN75849.1 xref: EMBL:AAN75850.1 xref: UniProtKB:Q8IVH7 xref: UniProtKB:Q8IVH8 xref: UniProtKB:Q9UDM5 xref: UniProtKB:Q9Y6R5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018551 ! MAP4K3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000772 ! JNK cascade [Term] id: CCO:B0057346 name: ZN547_HUMAN def: "Zinc finger protein 547" [UniProtKB:Q8IVP9] xref: EMBL:AAH42681.2 xref: EMBL:BAB70979.1 xref: UniProtKB:Q8IVP9 xref: UniProtKB:Q96NC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020809 ! ZNF547_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057347 name: Q8IVS5_HUMAN def: "ZNF544 protein" [UniProtKB:Q8IVS5] xref: EMBL:AAH42177.1 xref: UniProtKB:Q8IVS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020807 ! ZNF544_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057348 name: KSR1_HUMAN def: "Kinase suppressor of Ras 1" [UniProtKB:Q8IVT5] xref: EMBL:AAC50354.1 xref: EMBL:AAH42106.1 xref: UniProtKB:Q13476 xref: UniProtKB:Q8IVT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018447 ! KSR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016210 ! map2k2-ksr-1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0067494 ! KSR1_HUMAN-Phosphothreonine268 relationship: transforms_into CCO:B0067495 ! KSR1_HUMAN-Phosphothreonine272 relationship: transforms_into CCO:B0067496 ! KSR1_HUMAN-Phosphoserine309 relationship: transforms_into CCO:B0067497 ! KSR1_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0067498 ! KSR1_HUMAN-Phosphoserine404 relationship: transforms_into CCO:B0067499 ! KSR1_HUMAN-Phosphoserine567 [Term] id: CCO:B0057349 name: ARI3B_HUMAN def: "AT-rich interactive domain-containing protein 3B" [UniProtKB:Q8IVW6] synonym: "ARID domain-containing protein 3B" EXACT [UniProtKB:Q8IVW6] synonym: "Bright and dead ringer protein" EXACT [UniProtKB:Q8IVW6] synonym: "Bright-like" EXACT [UniProtKB:Q8IVW6] xref: EMBL:AAD09133.1 xref: EMBL:AAH41792.1 xref: EMBL:AAH60824.1 xref: EMBL:BAD92067.1 xref: UniProtKB:O95443 xref: UniProtKB:Q59HC9 xref: UniProtKB:Q6P9C9 xref: UniProtKB:Q8IVW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017029 ! ARID3B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063577 ! ARI3B_HUMAN-Phosphoserine89 [Term] id: CCO:B0057350 name: Q8IVW9_HUMAN def: "Diacylglycerol kinase, zeta 104kDa" [UniProtKB:Q8IVW9] xref: EMBL:AAH41770.1 xref: UniProtKB:Q8IVW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017573 ! DGKZ_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057351 name: Q8IVY6_HUMAN def: "ZNF551 protein" [UniProtKB:Q8IVY6] xref: EMBL:AAH41615.1 xref: UniProtKB:Q8IVY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011801 ! ZNF551_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057352 name: Q8IW13_HUMAN def: "NR1H3 protein" [UniProtKB:Q8IW13] synonym: "Nuclear receptor subfamily 1, group H, member 3, isoform CRA_a" EXACT [UniProtKB:Q8IW13] xref: EMBL:AAH41172.1 xref: EMBL:EAW67942.1 xref: UniProtKB:Q8IW13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018852 ! NR1H3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057353 name: ZN695_HUMAN def: "Zinc finger protein 695" [UniProtKB:Q8IW36] synonym: "Zinc finger protein SBZF3" EXACT [UniProtKB:Q8IW36] xref: EMBL:AAH23527.1 xref: EMBL:AAH41082.2 xref: EMBL:AAH55096.1 xref: EMBL:CAI15612.1 xref: UniProtKB:Q5T0N9 xref: UniProtKB:Q5T0P1 xref: UniProtKB:Q5T0P3 xref: UniProtKB:Q7Z2W8 xref: UniProtKB:Q7Z648 xref: UniProtKB:Q8IW36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020902 ! ZNF695_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057354 name: Q8IW90_HUMAN def: "MTCH1 protein" [UniProtKB:Q8IW90] xref: EMBL:AAH40659.2 xref: UniProtKB:Q8IW90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018673 ! MTCH1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0057355 name: ARHGJ_HUMAN def: "Rho guanine nucleotide exchange factor 19" [UniProtKB:Q8IW93] xref: EMBL:AAH12982.1 xref: EMBL:AAH40640.1 xref: EMBL:BAC03627.1 xref: EMBL:CAI22566.1 xref: EMBL:CAI22567.1 xref: UniProtKB:A6NJ04 xref: UniProtKB:Q5TEV2 xref: UniProtKB:Q6PJQ4 xref: UniProtKB:Q8IW93 xref: UniProtKB:Q8N244 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017025 ! ARHGEF19_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057356 name: CTL2_HUMAN def: "Choline transporter-like protein 2" [UniProtKB:Q8IWA5] synonym: "Solute carrier family 44 member 2" EXACT [UniProtKB:Q8IWA5] xref: EMBL:AAH10617.1 xref: EMBL:AAH40556.1 xref: EMBL:BAC11662.1 xref: EMBL:CAB75542.1 xref: EMBL:CAH56342.1 xref: EMBL:CAH56352.1 xref: UniProtKB:Q658V1 xref: UniProtKB:Q658Z2 xref: UniProtKB:Q6PJV7 xref: UniProtKB:Q8IWA5 xref: UniProtKB:Q8N2F0 xref: UniProtKB:Q9NY68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017490 ! SLC44A2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0002691 ! choline transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0057357 name: Q8IWA7_HUMAN def: "RAB37, member RAS oncogene family" [UniProtKB:Q8IWA7] synonym: "cDNA FLJ75617, highly similar to Homo sapiens RAB37, member RAS oncogene family (RAB37), transcript variant 3, mRNA" EXACT [UniProtKB:Q8IWA7] synonym: "RAB37, member RAS oncogene family, isoform CRA_d" EXACT [UniProtKB:Q8IWA7] xref: EMBL:AAH40547.1 xref: EMBL:BAF82891.1 xref: EMBL:EAW89180.1 xref: UniProtKB:Q8IWA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057358 name: TEX2_HUMAN def: "Testis-expressed sequence 2 protein" [UniProtKB:Q8IWB9] xref: EMBL:AAH40521.1 xref: EMBL:BAB21829.2 xref: EMBL:CAD38927.1 xref: EMBL:CAH10519.1 xref: UniProtKB:Q6AHZ5 xref: UniProtKB:Q8IWB9 xref: UniProtKB:Q8N3L0 xref: UniProtKB:Q9C0C5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020235 ! TEX2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071345 ! TEX2_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0071346 ! TEX2_HUMAN-Phosphoserine196 relationship: transforms_into CCO:B0071347 ! TEX2_HUMAN-Phosphothreonine262 relationship: transforms_into CCO:B0071348 ! TEX2_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0071349 ! TEX2_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0071350 ! TEX2_HUMAN-Phosphothreonine269 relationship: transforms_into CCO:B0071351 ! TEX2_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0071352 ! TEX2_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0071353 ! TEX2_HUMAN-Phosphotyrosine609 relationship: transforms_into CCO:B0071354 ! TEX2_HUMAN-Phosphoserine751 relationship: transforms_into CCO:B0071355 ! TEX2_HUMAN-Phosphoserine790 relationship: transforms_into CCO:B0071356 ! TEX2_HUMAN-Phosphoserine794 [Term] id: CCO:B0057359 name: Q8IWC5_HUMAN def: "RGS11 protein" [UniProtKB:Q8IWC5] synonym: "Regulator of G-protein signalling 11, isoform CRA_d" EXACT [UniProtKB:Q8IWC5] xref: EMBL:AAH40504.1 xref: EMBL:EAW85842.1 xref: UniProtKB:Q8IWC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019702 ! RGS11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057360 name: MGAP_HUMAN def: "MAX gene-associated protein" [UniProtKB:Q8IWI9] xref: EMBL:AAH38449.1 xref: EMBL:BAA25444.1 xref: EMBL:BAB14186.1 xref: EMBL:BAB14543.1 xref: EMBL:CAB43310.1 xref: UniProtKB:Q8IWI9 xref: UniProtKB:Q9H8R3 xref: UniProtKB:Q9H9N7 xref: UniProtKB:Q9UG69 xref: UniProtKB:Q9Y4E9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022398 ! MGA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068155 ! MGAP_HUMAN-Phosphoserine924 relationship: transforms_into CCO:B0068156 ! MGAP_HUMAN-Phosphoserine1208 relationship: transforms_into CCO:B0068157 ! MGAP_HUMAN-Phosphoserine1457 relationship: transforms_into CCO:B0068158 ! MGAP_HUMAN-Phosphoserine1973 [Term] id: CCO:B0057361 name: GP125_HUMAN def: "Probable G-protein coupled receptor 125 precursor" [UniProtKB:Q8IWK6] xref: EMBL:AAH26009.2 xref: EMBL:AAH35645.1 xref: EMBL:AAO27355.1 xref: EMBL:AAQ88673.1 xref: UniProtKB:Q6UXK9 xref: UniProtKB:Q86SQ5 xref: UniProtKB:Q8IWK6 xref: UniProtKB:Q8TC55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017964 ! GPR125_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0066524 ! GP125_HUMAN-Phosphothreonine208 [Term] id: CCO:B0057362 name: RP1L1_HUMAN def: "Retinitis pigmentosa 1-like 1 protein" [UniProtKB:Q8IWN7] xref: EMBL:AAN86959.1 xref: EMBL:AAN86960.1 xref: EMBL:AAN86961.1 xref: EMBL:AAN86962.1 xref: EMBL:AAN86963.1 xref: EMBL:AAN86964.1 xref: EMBL:BAC87029.1 xref: EMBL:CAD36957.1 xref: UniProtKB:Q86SQ1 xref: UniProtKB:Q8IWN7 xref: UniProtKB:Q8IWN8 xref: UniProtKB:Q8IWN9 xref: UniProtKB:Q8IWP0 xref: UniProtKB:Q8IWP1 xref: UniProtKB:Q8IWP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019774 ! RP1L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057363 name: PHF6_HUMAN def: "PHD finger protein 6" [UniProtKB:Q8IWS0] synonym: "PHD-like zinc finger protein" EXACT [UniProtKB:Q8IWS0] xref: EMBL:AAH05994.1 xref: EMBL:AAO13214.1 xref: EMBL:BAB47452.1 xref: EMBL:CAI41600.1 xref: UniProtKB:Q5JRC8 xref: UniProtKB:Q8IWS0 xref: UniProtKB:Q96JK3 xref: UniProtKB:Q9BRU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019381 ! PHF6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069257 ! PHF6_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0069258 ! PHF6_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0069259 ! PHF6_HUMAN-Phosphoserine145 relationship: transforms_into CCO:B0069260 ! PHF6_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0069261 ! PHF6_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0069262 ! PHF6_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0069263 ! PHF6_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0069264 ! PHF6_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0069265 ! PHF6_HUMAN-Phosphothreonine358 [Term] id: CCO:B0057364 name: LAX1_HUMAN def: "Lymphocyte transmembrane adapter 1" [UniProtKB:Q8IWV1] synonym: "Linker for activation of X cells" EXACT [UniProtKB:Q8IWV1] synonym: "Membrane-associated adapter protein LAX" EXACT [UniProtKB:Q8IWV1] xref: EMBL:AAH69650.1 xref: EMBL:AAH89408.1 xref: EMBL:AAM09818.1 xref: EMBL:BAA91101.1 xref: UniProtKB:Q6NSZ6 xref: UniProtKB:Q8IWV1 xref: UniProtKB:Q9NXB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018458 ! LAX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002986 ! negative regulation of T cell activation relationship: transforms_into CCO:B0067591 ! LAX1_HUMAN-Phosphotyrosine193 relationship: transforms_into CCO:B0067592 ! LAX1_HUMAN-Phosphotyrosine268 relationship: transforms_into CCO:B0067593 ! LAX1_HUMAN-Phosphotyrosine294 relationship: transforms_into CCO:B0067594 ! LAX1_HUMAN-Phosphotyrosine373 [Term] id: CCO:B0057365 name: CNTN4_HUMAN def: "Contactin-4 precursor" [UniProtKB:Q8IWV2] synonym: "BIG-2" EXACT [UniProtKB:Q8IWV2] synonym: "Brain-derived immunoglobulin superfamily protein 2" EXACT [UniProtKB:Q8IWV2] xref: EMBL:AAH26119.1 xref: EMBL:AAM00025.1 xref: EMBL:AAN86141.1 xref: EMBL:AAP05786.1 xref: UniProtKB:Q8IWV2 xref: UniProtKB:Q8IX14 xref: UniProtKB:Q8TC35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017415 ! CNTN4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0002479 ! negative regulation of neuron differentiation relationship: participates_in CCO:P0002784 ! regulation of synaptic plasticity [Term] id: CCO:B0057366 name: ZSC29_HUMAN def: "Zinc finger and SCAN domain-containing protein 29" [UniProtKB:Q8IWY8] synonym: "Zinc finger protein 690" EXACT [UniProtKB:Q8IWY8] xref: EMBL:AAI09271.1 xref: EMBL:AAI09272.1 xref: EMBL:AAO14995.1 xref: EMBL:BAC04088.1 xref: UniProtKB:Q32M75 xref: UniProtKB:Q32M76 xref: UniProtKB:Q8IWY8 xref: UniProtKB:Q8NA40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021006 ! ZSCAN29_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072279 ! ZSC29_HUMAN-Phosphoserine560 [Term] id: CCO:B0057367 name: FOG1_HUMAN def: "Zinc finger protein ZFPM1" [UniProtKB:Q8IX07] synonym: "FOG-1" EXACT [UniProtKB:Q8IX07] synonym: "Friend of GATA protein 1" EXACT [UniProtKB:Q8IX07] synonym: "Friend of GATA-1" EXACT [UniProtKB:Q8IX07] synonym: "Zinc finger protein multitype 1" EXACT [UniProtKB:Q8IX07] xref: EMBL:AAN45858.1 xref: UniProtKB:Q8IX07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017818 ! ZFPM1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066236 ! FOG1_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0066237 ! FOG1_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0066238 ! FOG1_HUMAN-Phosphoserine636 relationship: transforms_into CCO:B0066239 ! FOG1_HUMAN-Phosphothreonine651 relationship: transforms_into CCO:B0066240 ! FOG1_HUMAN-Phosphoserine664 relationship: transforms_into CCO:B0066241 ! FOG1_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0066242 ! FOG1_HUMAN-Phosphotyrosine696 relationship: transforms_into CCO:B0066243 ! FOG1_HUMAN-Phosphothreonine697 relationship: transforms_into CCO:B0066244 ! FOG1_HUMAN-Phosphoserine784 relationship: transforms_into CCO:B0066245 ! FOG1_HUMAN-Phosphoserine933 [Term] id: CCO:B0057368 name: HOMEZ_HUMAN def: "Homeobox and leucine zipper protein Homez" [UniProtKB:Q8IX15] synonym: "Homeodomain leucine zipper-containing factor" EXACT [UniProtKB:Q8IX15] xref: EMBL:AAH65835.1 xref: EMBL:AAN76991.1 xref: EMBL:BAA92681.1 xref: UniProtKB:Q6P049 xref: UniProtKB:Q86XB6 xref: UniProtKB:Q8IX15 xref: UniProtKB:Q9P2A5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018155 ! HOMEZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066890 ! HOMEZ_HUMAN-Phosphothreonine427 [Term] id: CCO:B0057369 name: SACA3_HUMAN def: "Sperm acrosome membrane-associated protein 3" [UniProtKB:Q8IXA5] synonym: "Cancer/testis antigen 54" EXACT [UniProtKB:Q8IXA5] synonym: "CT54" EXACT [UniProtKB:Q8IXA5] synonym: "Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17" EXACT [UniProtKB:Q8IXA5] synonym: "Lysozyme-like protein 3" EXACT [UniProtKB:Q8IXA5] synonym: "Sperm lysozyme-like protein 1" EXACT [UniProtKB:Q8IXA5] xref: EMBL:AAI00887.1 xref: EMBL:AAI00888.1 xref: EMBL:AAK01478.1 xref: EMBL:AAP97222.1 xref: EMBL:AAQ89016.1 xref: UniProtKB:Q7Z4Y5 xref: UniProtKB:Q8IXA5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019829 ! SPACA3_human relationship: has_function CCO:F0000326 ! lysozyme activity relationship: has_function CCO:F0001847 ! bacterial binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000194 ! acrosomal membrane relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000985 ! secretory granule relationship: participates_in CCO:P0002144 ! positive regulation of macrophage activation relationship: participates_in CCO:P0002944 ! positive regulation of phagocytosis [Term] id: CCO:B0057370 name: Q8IXD9_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8IXD9] xref: EMBL:BAC45264.1 xref: UniProtKB:Q8IXD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057371 name: Q8IXE0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8IXE0] xref: EMBL:BAC45263.1 xref: UniProtKB:Q8IXE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021230 ! OR11H13P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057372 name: OR4N5_HUMAN def: "Olfactory receptor 4N5" [UniProtKB:Q8IXE1] synonym: "Olfactory receptor OR14-33" EXACT [UniProtKB:Q8IXE1] xref: EMBL:BAC45262.1 xref: EMBL:DAA04849.1 xref: UniProtKB:Q6IF11 xref: UniProtKB:Q8IXE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019169 ! OR4N5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057373 name: Q8IXE4_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8IXE4] xref: EMBL:BAC45259.1 xref: UniProtKB:Q8IXE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057374 name: Q8IXE5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8IXE5] xref: EMBL:BAC45258.1 xref: UniProtKB:Q8IXE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057375 name: NPAS3_HUMAN def: "Neuronal PAS domain-containing protein 3" [UniProtKB:Q8IXF0] synonym: "Basic-helix-loop-helix-PAS protein MOP6" EXACT [UniProtKB:Q8IXF0] synonym: "Member of PAS protein 6" EXACT [UniProtKB:Q8IXF0] synonym: "Neuronal PAS3" EXACT [UniProtKB:Q8IXF0] xref: EMBL:AAG35180.1 xref: EMBL:AAO17043.1 xref: EMBL:AAO17044.1 xref: EMBL:BAB21221.1 xref: EMBL:BAC53754.1 xref: EMBL:BAC53756.1 xref: EMBL:CAB45154.1 xref: UniProtKB:Q86US6 xref: UniProtKB:Q86US7 xref: UniProtKB:Q8IXF0 xref: UniProtKB:Q8IXF2 xref: UniProtKB:Q9BY81 xref: UniProtKB:Q9H323 xref: UniProtKB:Q9Y4L8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018828 ! NPAS3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057376 name: NELFD_HUMAN def: "Negative elongation factor C/D" [UniProtKB:Q8IXH7] synonym: "NELF-C/D" EXACT [UniProtKB:Q8IXH7] synonym: "TH1-like protein" EXACT [UniProtKB:Q8IXH7] xref: EMBL:AAF29094.1 xref: EMBL:AAH14952.1 xref: EMBL:BAA91618.1 xref: EMBL:BAB14519.1 xref: EMBL:BAB14729.1 xref: EMBL:BAC86976.1 xref: EMBL:CAB64337.1 xref: EMBL:CAB64339.1 xref: EMBL:CAB64373.1 xref: EMBL:CAC09368.1 xref: UniProtKB:Q8IXH7 xref: UniProtKB:Q9BYL2 xref: UniProtKB:Q9H405 xref: UniProtKB:Q9H888 xref: UniProtKB:Q9H8T3 xref: UniProtKB:Q9NVX5 xref: UniProtKB:Q9P029 xref: UniProtKB:Q9UGN1 xref: UniProtKB:Q9UGN2 xref: UniProtKB:Q9UGN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018751 ! TH1L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0018047 ! araf-th1l-1 physical interaction relationship: participates_in CCO:I0018800 ! araf-th1l physical interaction relationship: participates_in CCO:I0018807 ! araf-th1l-2 physical interaction relationship: participates_in CCO:I0018815 ! araf-th1l-3 physical interaction relationship: participates_in CCO:I0019853 ! th1l-mta1 physical interaction relationship: participates_in CCO:I0020192 ! th1l-dnaja1 physical interaction relationship: participates_in CCO:I0020193 ! th1l-gstm4 physical interaction relationship: participates_in CCO:I0020194 ! th1l-hdac11 physical interaction relationship: participates_in CCO:I0020477 ! th1l-arpc4 physical interaction relationship: participates_in CCO:I0020478 ! th1l-eprs physical interaction relationship: participates_in CCO:I0020479 ! th1l-serf2 physical interaction relationship: participates_in CCO:I0020677 ! th1l-aamp physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0057377 name: MIRO2_HUMAN def: "Mitochondrial Rho GTPase 2" [UniProtKB:Q8IXI1] synonym: "EC 3.6.5.-" EXACT [UniProtKB:Q8IXI1] synonym: "hMiro-2" EXACT [UniProtKB:Q8IXI1] synonym: "MIRO-2" EXACT [UniProtKB:Q8IXI1] synonym: "Ras homolog gene family member T2" EXACT [UniProtKB:Q8IXI1] xref: EMBL:AAH04327.1 xref: EMBL:AAH14942.1 xref: EMBL:AAK61240.1 xref: EMBL:AAP46090.1 xref: EMBL:BAB15740.1 xref: EMBL:BAC03407.1 xref: EMBL:CAD56957.1 xref: UniProtKB:Q8IXI1 xref: UniProtKB:Q8NF53 xref: UniProtKB:Q96C13 xref: UniProtKB:Q96S17 xref: UniProtKB:Q9BT60 xref: UniProtKB:Q9H7M8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018625 ! RHOT2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: located_in CCO:C0001194 ! integral to mitochondrial outer membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057378 name: MIRO1_HUMAN def: "Mitochondrial Rho GTPase 1" [UniProtKB:Q8IXI2] synonym: "EC 3.6.5.-" EXACT [UniProtKB:Q8IXI2] synonym: "hMiro-1" EXACT [UniProtKB:Q8IXI2] synonym: "MIRO-1" EXACT [UniProtKB:Q8IXI2] synonym: "Rac-GTP-binding protein-like protein" EXACT [UniProtKB:Q8IXI2] synonym: "Ras homolog gene family member T1" EXACT [UniProtKB:Q8IXI2] xref: EMBL:AAH15698.1 xref: EMBL:AAH41114.1 xref: EMBL:AAH51818.1 xref: EMBL:AAH60781.2 xref: EMBL:AAH68463.1 xref: EMBL:AAI25105.1 xref: EMBL:AAI25106.1 xref: EMBL:AAM15734.1 xref: EMBL:BAA91969.1 xref: EMBL:BAB14185.1 xref: EMBL:CAB66863.1 xref: EMBL:CAD43139.1 xref: EMBL:CAD56956.1 xref: UniProtKB:A4FVB6 xref: UniProtKB:A6NFV0 xref: UniProtKB:Q6NUR3 xref: UniProtKB:Q6P9F8 xref: UniProtKB:Q6PJG1 xref: UniProtKB:Q6YMW8 xref: UniProtKB:Q86UB0 xref: UniProtKB:Q8IW28 xref: UniProtKB:Q8IXI2 xref: UniProtKB:Q8IXJ7 xref: UniProtKB:Q9H067 xref: UniProtKB:Q9H9N8 xref: UniProtKB:Q9NUZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018624 ! RHOT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: located_in CCO:C0001194 ! integral to mitochondrial outer membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057379 name: ASXL1_HUMAN def: "Putative Polycomb group protein ASXL1" [UniProtKB:Q8IXJ9] synonym: "Additional sex combs-like protein 1" EXACT [UniProtKB:Q8IXJ9] xref: EMBL:AAH33284.1 xref: EMBL:BAA76822.2 xref: EMBL:CAB55975.1 xref: EMBL:CAB56029.2 xref: EMBL:CAD27708.1 xref: EMBL:CAI40414.1 xref: EMBL:CAI42259.1 xref: UniProtKB:Q5JWS9 xref: UniProtKB:Q8IXJ9 xref: UniProtKB:Q8IYY7 xref: UniProtKB:Q9H466 xref: UniProtKB:Q9NQF8 xref: UniProtKB:Q9UFJ0 xref: UniProtKB:Q9UFP8 xref: UniProtKB:Q9Y2I4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017085 ! ASXL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063633 ! ASXL1_HUMAN-Phosphoserine503 [Term] id: CCO:B0057380 name: PALM2_HUMAN def: "Paralemmin-2" [UniProtKB:Q8IXS6] xref: EMBL:AAH39306.2 xref: EMBL:BAC04472.1 xref: EMBL:CAC59693.1 xref: EMBL:CAH73567.1 xref: EMBL:CAI10810.1 xref: EMBL:CAI10812.1 xref: EMBL:CAI12433.1 xref: EMBL:CAI12435.1 xref: EMBL:CAI13895.1 xref: EMBL:CAI13897.1 xref: UniProtKB:A9Z1X9 xref: UniProtKB:Q8IXS6 xref: UniProtKB:Q8N9D5 xref: UniProtKB:Q96DU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019295 ! PALM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0069078 ! PALM2_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0069079 ! PALM2_HUMAN-Phosphoserine358 [Term] id: CCO:B0057381 name: DMRTD_HUMAN def: "Doublesex- and mab-3-related transcription factor C2" [UniProtKB:Q8IXT2] xref: EMBL:AAH29202.1 xref: EMBL:AAH39266.1 xref: EMBL:BAB71473.1 xref: EMBL:CAC40652.1 xref: UniProtKB:Q8IXT2 xref: UniProtKB:Q8N6Q2 xref: UniProtKB:Q96M39 xref: UniProtKB:Q96SD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017593 ! DMRTC2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057382 name: Q8IY43_HUMAN def: "CRADD protein" [UniProtKB:Q8IY43] xref: EMBL:AAH37905.1 xref: UniProtKB:Q8IY43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004393 ! CRADD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0057383 name: TIGD4_HUMAN def: "Tigger transposable element-derived protein 4" [UniProtKB:Q8IY51] xref: EMBL:AAH37869.1 xref: EMBL:BAB71642.1 xref: UniProtKB:Q8IY51 xref: UniProtKB:Q96LP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020268 ! TIGD4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0071405 ! TIGD4_HUMAN-Phosphotyrosine375 relationship: transforms_into CCO:B0071406 ! TIGD4_HUMAN-Phosphoserine382 [Term] id: CCO:B0057384 name: YAF2_HUMAN def: "YY1-associated factor 2" [UniProtKB:Q8IY57] xref: EMBL:AAC51116.1 xref: EMBL:AAH37777.1 xref: UniProtKB:Q8IY57 xref: UniProtKB:Q99710 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020511 ! YAF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0071900 ! YAF2_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0071901 ! YAF2_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0071902 ! YAF2_HUMAN-Phosphoserine167 [Term] id: CCO:B0057385 name: ZN595_HUMAN def: "Zinc finger protein 595" [UniProtKB:Q8IYB9] xref: EMBL:AAH36110.1 xref: EMBL:AAH43151.1 xref: UniProtKB:Q8IYB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020845 ! ZNF595_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057386 name: ELOA2_HUMAN def: "RNA polymerase II transcription factor SIII subunit A2" [UniProtKB:Q8IYF1] synonym: "EloA2" EXACT [UniProtKB:Q8IYF1] synonym: "Elongin-A2" EXACT [UniProtKB:Q8IYF1] synonym: "Transcription elongation factor B polypeptide 3B" EXACT [UniProtKB:Q8IYF1] xref: EMBL:AAH36022.1 xref: EMBL:BAA90665.1 xref: UniProtKB:Q8IYF1 xref: UniProtKB:Q9P2V9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017694 ! TCEB3B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015011 ! tceb3b-znf165 physical interaction relationship: participates_in CCO:I0015027 ! tceb3b-trim37 physical interaction relationship: participates_in CCO:I0015087 ! tceb3b-traf2 physical interaction relationship: participates_in CCO:I0015157 ! mgc2749-tceb3b physical interaction relationship: participates_in CCO:I0015214 ! tceb3b-znf297b physical interaction relationship: participates_in CCO:I0015351 ! dvl2-tceb3b physical interaction relationship: participates_in CCO:I0015561 ! ndp52-tceb3b physical interaction relationship: participates_in CCO:I0015732 ! cep70-tceb3b physical interaction relationship: participates_in CCO:I0015746 ! krtap4_12-tceb3b physical interaction relationship: participates_in CCO:I0015756 ! cbx5-tceb3b physical interaction relationship: participates_in CCO:I0017577 ! tceb3b-coil physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057387 name: ZZZ3_HUMAN def: "ZZ-type zinc finger-containing protein 3" [UniProtKB:Q8IYH5] xref: EMBL:AAH35079.1 xref: EMBL:AAH35397.1 xref: EMBL:AAH35818.1 xref: EMBL:BAB84945.1 xref: EMBL:CAB45694.1 xref: EMBL:CAE45800.1 xref: EMBL:CAE45870.1 xref: EMBL:CAE46004.1 xref: UniProtKB:Q6N004 xref: UniProtKB:Q6N070 xref: UniProtKB:Q8IYH5 xref: UniProtKB:Q8IYP0 xref: UniProtKB:Q8IYR1 xref: UniProtKB:Q8TEK4 xref: UniProtKB:Q9Y4U0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021013 ! ZZZ3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072286 ! ZZZ3_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0072287 ! ZZZ3_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0072288 ! ZZZ3_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0072289 ! ZZZ3_HUMAN-Phosphoserine474 [Term] id: CCO:B0057388 name: ZN440_HUMAN def: "Zinc finger protein 440" [UniProtKB:Q8IYI8] xref: EMBL:AAH35760.1 xref: EMBL:BAC04510.1 xref: UniProtKB:Q8IYI8 xref: UniProtKB:Q8N1R9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020752 ! ZNF440_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015589 ! mdfi-znf440 physical interaction relationship: participates_in CCO:I0015766 ! krtap4_12-znf440 physical interaction relationship: participates_in CCO:I0020626 ! pja1-znf440 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057389 name: REM2_HUMAN def: "GTP-binding protein REM 2" [UniProtKB:Q8IYK8] synonym: "Rad and Gem-like GTP-binding protein 2" EXACT [UniProtKB:Q8IYK8] xref: EMBL:AAH35663.1 xref: EMBL:BAC04746.1 xref: UniProtKB:Q8IYK8 xref: UniProtKB:Q8N8R8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019669 ! REM2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057390 name: TRI22_HUMAN def: "Tripartite motif-containing protein 22" [UniProtKB:Q8IYM9] synonym: "50 kDa-stimulated trans-acting factor" EXACT [UniProtKB:Q8IYM9] synonym: "RING finger protein 94" EXACT [UniProtKB:Q8IYM9] synonym: "Staf-50" EXACT [UniProtKB:Q8IYM9] xref: EMBL:AAH35582.1 xref: EMBL:CAA57684.1 xref: UniProtKB:Q15521 xref: UniProtKB:Q8IYM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020354 ! TRIM22_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017572 ! trim22-cic physical interaction relationship: participates_in CCO:I0017582 ! trim22-rere physical interaction relationship: participates_in CCO:I0017593 ! trim22-usp7 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057391 name: TCAL8_HUMAN def: "Transcription elongation factor A protein-like 8" [UniProtKB:Q8IYN2] synonym: "TCEA-like protein 8" EXACT [UniProtKB:Q8IYN2] synonym: "Transcription elongation factor S-II protein-like 8" EXACT [UniProtKB:Q8IYN2] xref: EMBL:AAH35573.1 xref: EMBL:CAI41979.1 xref: UniProtKB:Q8IYN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020207 ! TCEAL8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057392 name: Q8IYN9_HUMAN def: "PTK2 protein" [UniProtKB:Q8IYN9] xref: EMBL:AAH35404.1 xref: UniProtKB:Q8IYN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004606 ! PTK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: participates_in CCO:P0000714 ! signal complex assembly [Term] id: CCO:B0057393 name: ZN679_HUMAN def: "Zinc finger protein 679" [UniProtKB:Q8IYX0] xref: EMBL:AAH33523.1 xref: UniProtKB:Q8IYX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020894 ! ZNF679_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015191 ! mdfi-znf679 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057394 name: TBC21_HUMAN def: "TBC1 domain family member 21" [UniProtKB:Q8IYX1] xref: EMBL:AAH33516.1 xref: UniProtKB:Q8IYX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020164 ! TBC1D21_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057395 name: ZN683_HUMAN def: "Zinc finger protein 683" [UniProtKB:Q8IZ20] xref: EMBL:AAH28731.2 xref: EMBL:AAH29505.1 xref: EMBL:CAI15853.2 xref: EMBL:CAI15854.2 xref: EMBL:CAI15855.2 xref: EMBL:CAI15856.2 xref: EMBL:CAI15857.2 xref: EMBL:CAI15858.2 xref: UniProtKB:Q5T141 xref: UniProtKB:Q5T146 xref: UniProtKB:Q5T147 xref: UniProtKB:Q5T149 xref: UniProtKB:Q8IZ20 xref: UniProtKB:Q8NEN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020896 ! ZNF683_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057396 name: ZNF34_HUMAN def: "Zinc finger protein 34" [UniProtKB:Q8IZ26] synonym: "Zinc finger protein KOX32" EXACT [UniProtKB:Q8IZ26] xref: EMBL:AAH04480.1 xref: EMBL:AAH28136.1 xref: EMBL:CAD38677.1 xref: UniProtKB:Q8IZ26 xref: UniProtKB:Q9BSZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020971 ! ZNF34_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057397 name: RCOR2_HUMAN def: "REST corepressor 2" [UniProtKB:Q8IZ40] xref: EMBL:AAH10608.1 xref: EMBL:AAH23587.1 xref: UniProtKB:Q8IZ40 xref: UniProtKB:Q96FP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019660 ! RCOR2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020512 ! arr3-rcor2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057398 name: RASEF_HUMAN def: "RAS and EF-hand domain-containing protein" [UniProtKB:Q8IZ41] synonym: "Ras-related protein Rab-45" EXACT [UniProtKB:Q8IZ41] xref: EMBL:AAH23566.1 xref: EMBL:BAB71112.1 xref: EMBL:CAH70678.1 xref: EMBL:CAH70679.1 xref: EMBL:EAW62643.1 xref: UniProtKB:A6NC29 xref: UniProtKB:Q8IZ41 xref: UniProtKB:Q96N04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019625 ! RASEF_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069751 ! RASEF_HUMAN-Phosphoserine523 relationship: transforms_into CCO:B0069752 ! RASEF_HUMAN-Phosphothreonine526 [Term] id: CCO:B0057399 name: Q8IZB1_HUMAN def: "Dopamine receptor D4" [UniProtKB:Q8IZB1] xref: EMBL:AAN73264.1 xref: UniProtKB:Q8IZB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017620 ! DRD4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057400 name: RTKN2_HUMAN def: "Rhotekin-2" [UniProtKB:Q8IZC4] synonym: "Pleckstrin homology domain-containing family K member 1" EXACT [UniProtKB:Q8IZC4] xref: EMBL:AAH25765.1 xref: EMBL:AAH48002.1 xref: EMBL:AAI41822.1 xref: EMBL:AAI42726.1 xref: EMBL:AAN71738.1 xref: EMBL:BAC04837.1 xref: EMBL:CAH18074.1 xref: EMBL:CAI15189.1 xref: EMBL:EAW54232.1 xref: UniProtKB:Q3ZCR1 xref: UniProtKB:Q68DZ6 xref: UniProtKB:Q8IZC4 xref: UniProtKB:Q8N8K1 xref: UniProtKB:Q8TAV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019809 ! RTKN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057401 name: ZN101_HUMAN def: "Zinc finger protein 101" [UniProtKB:Q8IZC7] synonym: "HZF12" EXACT [UniProtKB:Q8IZC7] synonym: "Zinc finger protein 12" EXACT [UniProtKB:Q8IZC7] xref: EMBL:AAN46749.1 xref: UniProtKB:Q8IZC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020616 ! ZNF101_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072048 ! ZN101_HUMAN-Phosphoserine433 [Term] id: CCO:B0057402 name: GP116_HUMAN def: "Probable G-protein coupled receptor 116 precursor" [UniProtKB:Q8IZF2] xref: EMBL:AAH66121.1 xref: EMBL:AAN46672.1 xref: EMBL:AAO85064.1 xref: EMBL:AAS21061.1 xref: EMBL:BAA34478.2 xref: EMBL:CAB43394.1 xref: UniProtKB:O94858 xref: UniProtKB:Q6RGN2 xref: UniProtKB:Q86SP0 xref: UniProtKB:Q8IZF2 xref: UniProtKB:Q9Y3Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017959 ! GPR116_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0066523 ! GP116_HUMAN-Phosphothreonine221 [Term] id: CCO:B0057403 name: GP115_HUMAN def: "Probable G-protein coupled receptor 115 precursor" [UniProtKB:Q8IZF3] synonym: "G-protein coupled receptor PGR18" EXACT [UniProtKB:Q8IZF3] xref: EMBL:AAN46671.1 xref: EMBL:AAO85068.1 xref: EMBL:ABC41929.1 xref: EMBL:BAC45257.1 xref: EMBL:CAI15579.1 xref: EMBL:CAI15581.1 xref: UniProtKB:Q2PNZ0 xref: UniProtKB:Q5T5B5 xref: UniProtKB:Q5T5B6 xref: UniProtKB:Q86SN9 xref: UniProtKB:Q8IXE6 xref: UniProtKB:Q8IZF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017958 ! GPR115_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057404 name: GP114_HUMAN def: "Probable G-protein coupled receptor 114 precursor" [UniProtKB:Q8IZF4] synonym: "G-protein coupled receptor PGR27" EXACT [UniProtKB:Q8IZF4] xref: EMBL:AAH32401.1 xref: EMBL:AAN46670.1 xref: EMBL:AAO85121.1 xref: EMBL:AAQ88812.1 xref: EMBL:BAD18711.1 xref: EMBL:BAD18748.1 xref: UniProtKB:Q6ZMH7 xref: UniProtKB:Q6ZML4 xref: UniProtKB:Q86SL8 xref: UniProtKB:Q8IZ14 xref: UniProtKB:Q8IZF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017957 ! GPR114_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057405 name: GP113_HUMAN def: "Probable G-protein coupled receptor 113 precursor" [UniProtKB:Q8IZF5] synonym: "G-protein coupled receptor PGR23" EXACT [UniProtKB:Q8IZF5] xref: EMBL:AAN46669.1 xref: EMBL:AAO85123.1 xref: EMBL:AAQ88539.1 xref: EMBL:AAQ88581.1 xref: EMBL:BAB89332.1 xref: EMBL:BAC45265.1 xref: UniProtKB:Q6UXT7 xref: UniProtKB:Q6UXX3 xref: UniProtKB:Q86SL7 xref: UniProtKB:Q8IXD8 xref: UniProtKB:Q8IZF5 xref: UniProtKB:Q8TDT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017956 ! GPR113_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057406 name: GP111_HUMAN def: "Probable G-protein coupled receptor 111" [UniProtKB:Q8IZF7] synonym: "G-protein coupled receptor PGR20" EXACT [UniProtKB:Q8IZF7] xref: EMBL:AAN46667.1 xref: EMBL:AAO85124.1 xref: EMBL:BAB89330.1 xref: EMBL:BAC05907.1 xref: EMBL:CAI15578.1 xref: UniProtKB:Q86SL6 xref: UniProtKB:Q8IZF7 xref: UniProtKB:Q8NGU5 xref: UniProtKB:Q8TDT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017955 ! GPR111_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057407 name: UNC5B_HUMAN def: "Netrin receptor UNC5B precursor" [UniProtKB:Q8IZJ1] synonym: "p53-regulated receptor for death and life protein 1" EXACT [UniProtKB:Q8IZJ1] synonym: "Protein unc-5 homolog B" EXACT [UniProtKB:Q8IZJ1] synonym: "Unc-5 homolog 2" EXACT [UniProtKB:Q8IZJ1] xref: EMBL:AAM95701.1 xref: EMBL:AAQ88717.1 xref: EMBL:BAB14276.1 xref: EMBL:BAC04382.1 xref: EMBL:BAC57998.1 xref: UniProtKB:Q86SN3 xref: UniProtKB:Q8IZJ1 xref: UniProtKB:Q8N1Y2 xref: UniProtKB:Q9H9F3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020413 ! UNC5B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057408 name: RGDSR_HUMAN def: "Ral-GDS-related protein" [UniProtKB:Q8IZJ4] synonym: "hRGR" EXACT [UniProtKB:Q8IZJ4] synonym: "RalGDS-like 4" EXACT [UniProtKB:Q8IZJ4] xref: EMBL:AAM51551.1 xref: UniProtKB:Q8IZJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019690 ! RGL4_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057409 name: MAML2_HUMAN def: "Mastermind-like protein 2" [UniProtKB:Q8IZL2] synonym: "Mam-2" EXACT [UniProtKB:Q8IZL2] xref: EMBL:AAI52450.1 xref: EMBL:AAK93831.1 xref: EMBL:AAK93833.1 xref: EMBL:AAP12462.1 xref: EMBL:AAP12463.1 xref: EMBL:BAB47448.1 xref: EMBL:CAH10491.1 xref: UniProtKB:A7MD26 xref: UniProtKB:Q6AI23 xref: UniProtKB:Q6Y3A3 xref: UniProtKB:Q8IUL3 xref: UniProtKB:Q8IZL2 xref: UniProtKB:Q96JK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018564 ! MAML2_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0057410 name: ZN654_HUMAN def: "Zinc finger protein 654" [UniProtKB:Q8IZM8] synonym: "Melanoma-associated antigen" EXACT [UniProtKB:Q8IZM8] xref: EMBL:AAN40504.1 xref: EMBL:BAA91946.1 xref: EMBL:BAB15007.1 xref: UniProtKB:Q8IZM8 xref: UniProtKB:Q9H791 xref: UniProtKB:Q9NV14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020877 ! ZNF654_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072208 ! ZN654_HUMAN-Phosphoserine576 relationship: transforms_into CCO:B0072209 ! ZN654_HUMAN-Phosphoserine580 [Term] id: CCO:B0057411 name: TBC3A_HUMAN def: "TBC1 domain family member 3" [UniProtKB:Q8IZP1] synonym: "Prostate cancer gene 17 protein" EXACT [UniProtKB:Q8IZP1] synonym: "Rab GTPase-activating protein PRC17" EXACT [UniProtKB:Q8IZP1] synonym: "TRE17 alpha protein" EXACT [UniProtKB:Q8IZP1] xref: EMBL:AAN33117.1 xref: EMBL:CAB66794.1 xref: EMBL:CAB94197.1 xref: UniProtKB:A6NGX2 xref: UniProtKB:Q8IZP1 xref: UniProtKB:Q9H0B9 xref: UniProtKB:Q9UDD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020172 ! TBC1D3_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057412 name: MYCD_HUMAN def: "Myocardin" [UniProtKB:Q8IZQ8] xref: EMBL:AAN33040.1 xref: EMBL:BAC05177.1 xref: UniProtKB:Q8IZQ8 xref: UniProtKB:Q8N7Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018690 ! MYOCD_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019352 ! srf-myocd-1 physical interaction relationship: participates_in CCO:I0019353 ! srf-myocd-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057413 name: Q8N0W0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8N0W0] xref: EMBL:BAC05731.1 xref: EMBL:BAC05837.1 xref: UniProtKB:Q8N0W0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057414 name: Q8N0W1_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8N0W1] xref: EMBL:BAC05791.1 xref: EMBL:BAC05804.1 xref: UniProtKB:Q8N0W1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057415 name: Q8N0X1_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8N0X1] xref: EMBL:BAC05880.1 xref: EMBL:BAC06120.1 xref: UniProtKB:Q8N0X1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057416 name: ZN444_HUMAN def: "Zinc finger protein 444" [UniProtKB:Q8N0Y2] synonym: "Endothelial zinc finger protein 2" EXACT [UniProtKB:Q8N0Y2] synonym: "EZF-2" EXACT [UniProtKB:Q8N0Y2] synonym: "Zinc finger and SCAN domain-containing protein 17" EXACT [UniProtKB:Q8N0Y2] xref: EMBL:AAH21282.1 xref: EMBL:BAA92028.1 xref: EMBL:BAB84889.1 xref: EMBL:BAC02697.1 xref: EMBL:BAC02698.1 xref: EMBL:CAD38847.1 xref: UniProtKB:Q8N0Y2 xref: UniProtKB:Q8TEQ9 xref: UniProtKB:Q8WU35 xref: UniProtKB:Q9NUU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020755 ! ZNF444_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072126 ! ZN444_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0072127 ! ZN444_HUMAN-Phosphoserine235 [Term] id: CCO:B0057417 name: OR4N4_HUMAN def: "Olfactory receptor 4N4" [UniProtKB:Q8N0Y3] synonym: "Olfactory receptor OR15-1" EXACT [UniProtKB:Q8N0Y3] xref: EMBL:BAC05879.1 xref: EMBL:BAC06119.1 xref: EMBL:DAA04804.1 xref: UniProtKB:Q6IF56 xref: UniProtKB:Q8N0Y3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019168 ! OR4N4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057418 name: OR8I2_HUMAN def: "Olfactory receptor 8I2" [UniProtKB:Q8N0Y5] synonym: "Olfactory receptor OR11-170" EXACT [UniProtKB:Q8N0Y5] xref: EMBL:AAK94998.1 xref: EMBL:BAC05882.1 xref: EMBL:BAC06062.1 xref: EMBL:DAA04740.1 xref: UniProtKB:Q6IFC0 xref: UniProtKB:Q8N0Y5 xref: UniProtKB:Q96RC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019228 ! OR8I2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057419 name: ABRA_HUMAN def: "Actin-binding Rho-activating protein" [UniProtKB:Q8N0Z2] synonym: "STARS" EXACT [UniProtKB:Q8N0Z2] synonym: "Striated muscle activator of Rho-dependent signaling" EXACT [UniProtKB:Q8N0Z2] xref: EMBL:AAI05104.1 xref: EMBL:AAI05106.1 xref: EMBL:AAM27268.1 xref: EMBL:BAC03948.1 xref: UniProtKB:Q8N0Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016875 ! ABRA_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000933 ! sarcomere relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001987 ! positive regulation of Rho protein signal transduction relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0003022 ! positive regulation of transcription factor activity [Term] id: CCO:B0057420 name: ATOH7_HUMAN def: "Protein atonal homolog 7" [UniProtKB:Q8N100] synonym: "Helix-loop-helix protein hATH-5" EXACT [UniProtKB:Q8N100] xref: EMBL:AAH32621.1 xref: EMBL:AAL11911.1 xref: EMBL:DAA01057.1 xref: UniProtKB:Q8N100 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017100 ! ATOH7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057421 name: SHSA5_HUMAN def: "Protein shisa-5 precursor" [UniProtKB:Q8N114] synonym: "Putative NF-kappa-B-activating protein 120" EXACT [UniProtKB:Q8N114] synonym: "Scotin" EXACT [UniProtKB:Q8N114] xref: EMBL:AAH01463.2 xref: EMBL:AAM74232.1 xref: EMBL:AAM74235.1 xref: EMBL:BAB71152.1 xref: EMBL:BAC11623.1 xref: EMBL:BAC77360.1 xref: EMBL:CAH10587.1 xref: EMBL:CAH10718.1 xref: EMBL:EAW64885.1 xref: EMBL:EAW64887.1 xref: UniProtKB:Q69YY9 xref: UniProtKB:Q7Z433 xref: UniProtKB:Q8N114 xref: UniProtKB:Q8NHL9 xref: UniProtKB:Q96MW8 xref: UniProtKB:Q9BV58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019902 ! SHISA5_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0057422 name: ZFP82_HUMAN def: "Zinc finger protein 82 homolog" [UniProtKB:Q8N141] synonym: "Zfp-82" EXACT [UniProtKB:Q8N141] synonym: "Zinc finger protein 545" EXACT [UniProtKB:Q8N141] xref: EMBL:AAH32577.1 xref: EMBL:BAB85534.1 xref: EMBL:BAC11308.1 xref: EMBL:CAD38942.1 xref: UniProtKB:Q8N141 xref: UniProtKB:Q8NC63 xref: UniProtKB:Q8TF53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022802 ! ZFP82_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057423 name: LIRA2_HUMAN def: "Leukocyte immunoglobulin-like receptor subfamily A member 2 precursor" [UniProtKB:Q8N149] synonym: "CD85 antigen-like family member H" EXACT [UniProtKB:Q8N149] synonym: "CD85h antigen" EXACT [UniProtKB:Q8N149] synonym: "ILT-1" EXACT [UniProtKB:Q8N149] synonym: "Immunoglobulin-like transcript 1" EXACT [UniProtKB:Q8N149] synonym: "Leukocyte immunoglobulin-like receptor 7" EXACT [UniProtKB:Q8N149] synonym: "LIR-7" EXACT [UniProtKB:Q8N149] xref: EMBL:AAB87665.1 xref: EMBL:AAH17412.1 xref: EMBL:AAH27916.1 xref: UniProtKB:O75020 xref: UniProtKB:Q8N149 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018496 ! LILRA2_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057424 name: Q8N164_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8N164] xref: EMBL:BAC05881.1 xref: EMBL:BAC06061.1 xref: UniProtKB:Q8N164 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057425 name: AL2S8_HUMAN def: "Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein" [UniProtKB:Q8N187] synonym: "Calcium-response factor" EXACT [UniProtKB:Q8N187] synonym: "CaRF" EXACT [UniProtKB:Q8N187] synonym: "Testis development protein NYD-SP24" EXACT [UniProtKB:Q8N187] xref: EMBL:AAH33777.1 xref: EMBL:AAK66819.2 xref: EMBL:AAL62330.1 xref: EMBL:AAY24288.1 xref: EMBL:BAB15088.1 xref: EMBL:BAB69018.1 xref: EMBL:BAB69019.1 xref: EMBL:CAD38882.2 xref: UniProtKB:Q8N187 xref: UniProtKB:Q8ND29 xref: UniProtKB:Q8WXC0 xref: UniProtKB:Q96J78 xref: UniProtKB:Q96Q38 xref: UniProtKB:Q96Q39 xref: UniProtKB:Q9H712 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016951 ! ALS2CR8_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0015188 ! als2cr8-lmo3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057426 name: SIX5_HUMAN def: "Homeobox protein SIX5" [UniProtKB:Q8N196] synonym: "DM locus-associated homeodomain protein" EXACT [UniProtKB:Q8N196] xref: EMBL:AAH33204.1 xref: UniProtKB:Q8N196 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019924 ! SIX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016185 ! atxn1-six5 physical interaction relationship: participates_in CCO:I0018981 ! atxn1-six5-1 physical interaction relationship: participates_in CCO:I0019008 ! atxn1-six5-2 physical interaction relationship: participates_in CCO:I0019059 ! atxn1-six5-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057427 name: ZN687_HUMAN def: "Zinc finger protein 687" [UniProtKB:Q8N1G0] xref: EMBL:AAH32463.1 xref: EMBL:BAA92679.1 xref: EMBL:BAB14406.1 xref: EMBL:CAH18162.1 xref: EMBL:CAH70322.1 xref: UniProtKB:Q68DQ8 xref: UniProtKB:Q8N1G0 xref: UniProtKB:Q9H937 xref: UniProtKB:Q9P2A7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020898 ! ZNF687_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072213 ! ZN687_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0072214 ! ZN687_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0072215 ! ZN687_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0072216 ! ZN687_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0072217 ! ZN687_HUMAN-Phosphoserine433 relationship: transforms_into CCO:B0072218 ! ZN687_HUMAN-Phosphothreonine900 relationship: transforms_into CCO:B0072219 ! ZN687_HUMAN-Phosphoserine1057 relationship: transforms_into CCO:B0072220 ! ZN687_HUMAN-Phosphoserine1082 relationship: transforms_into CCO:B0072221 ! ZN687_HUMAN-Phosphoserine1083 relationship: transforms_into CCO:B0072222 ! ZN687_HUMAN-Phosphoserine1085 relationship: transforms_into CCO:B0072223 ! ZN687_HUMAN-Phosphoserine1184 relationship: transforms_into CCO:B0072224 ! ZN687_HUMAN-Phosphoserine1191 relationship: transforms_into CCO:B0072225 ! ZN687_HUMAN-Phosphoserine1211 [Term] id: CCO:B0057428 name: S6OS1_HUMAN def: "Protein SIX6OS1" [UniProtKB:Q8N1H7] synonym: "Six6 opposite strand transcript 1" EXACT [UniProtKB:Q8N1H7] xref: EMBL:BAC05253.1 xref: UniProtKB:Q8N1H7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019826 ! SIX6OS1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0003021 ! regulation of transcription factor activity [Term] id: CCO:B0057429 name: Q8N1I7_HUMAN def: "cDNA FLJ40692 fis, clone THYMU2024748, highly similar to ZINC FINGER PROTEIN 135" [UniProtKB:Q8N1I7] synonym: "Zinc finger protein 135 (Clone pHZ-17), isoform CRA_b" EXACT [UniProtKB:Q8N1I7] xref: EMBL:BAC05214.1 xref: EMBL:EAW72553.1 xref: UniProtKB:Q8N1I7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020624 ! ZNF135_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057430 name: BATF2_HUMAN def: "Basic leucine zipper transcriptional factor ATF-like 2" [UniProtKB:Q8N1L9] synonym: "B-ATF-2" EXACT [UniProtKB:Q8N1L9] xref: EMBL:AAH12330.1 xref: EMBL:BAC04846.1 xref: UniProtKB:Q8N1L9 xref: UniProtKB:Q96EH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017129 ! BATF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057431 name: CRPAK_HUMAN def: "Cysteine-rich PAK1 inhibitor" [UniProtKB:Q8N1N5] synonym: "CRIPak" EXACT [UniProtKB:Q8N1N5] xref: EMBL:BAC03741.1 xref: EMBL:BAC04725.1 xref: UniProtKB:Q8N1N5 xref: UniProtKB:Q8NB03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017461 ! CRIPAK_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000685 ! ER-nuclear signaling pathway relationship: participates_in CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis [Term] id: CCO:B0057432 name: Q8N1T7_HUMAN xref: UniProtKB:Q8N1T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057433 name: RGNEF_HUMAN def: "Rho-guanine nucleotide exchange factor" [UniProtKB:Q8N1W1] synonym: "p190RhoGEF" EXACT [UniProtKB:Q8N1W1] xref: EMBL:AAH12946.1 xref: EMBL:BAB15141.1 xref: EMBL:BAB15243.1 xref: EMBL:BAC02707.1 xref: EMBL:BAC04405.1 xref: UniProtKB:Q8N1W1 xref: UniProtKB:Q8NCM7 xref: UniProtKB:Q96E37 xref: UniProtKB:Q9H6L3 xref: UniProtKB:Q9H6W0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019697 ! RGNEF_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0069917 ! RGNEF_HUMAN-Phosphoserine624 [Term] id: CCO:B0057434 name: ZN710_HUMAN def: "Zinc finger protein 710" [UniProtKB:Q8N1W2] xref: EMBL:AAI26477.1 xref: EMBL:AAI30542.1 xref: EMBL:BAC04404.1 xref: EMBL:BAD18716.1 xref: EMBL:CAD38540.1 xref: UniProtKB:A0AVS3 xref: UniProtKB:Q6ZMK9 xref: UniProtKB:Q8N1W2 xref: UniProtKB:Q8NDU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020913 ! ZNF710_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057435 name: Q8N1Y0_HUMAN def: "cDNA FLJ37293 fis, clone BRAMY2014813" [UniProtKB:Q8N1Y0] xref: EMBL:BAC04384.1 xref: UniProtKB:Q8N1Y0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057436 name: SCML4_HUMAN def: "Sex comb on midleg-like protein 4" [UniProtKB:Q8N228] xref: EMBL:AAH33286.1 xref: EMBL:BAC04198.1 xref: EMBL:CAI13630.1 xref: EMBL:CAI13632.1 xref: EMBL:CAI42848.1 xref: EMBL:CAQ08122.1 xref: EMBL:CAQ08123.1 xref: EMBL:EAW48394.1 xref: EMBL:EAW48395.1 xref: UniProtKB:B0QZ10 xref: UniProtKB:B0QZ11 xref: UniProtKB:Q5JXD0 xref: UniProtKB:Q5T0T6 xref: UniProtKB:Q8IYY6 xref: UniProtKB:Q8N228 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019850 ! SCML4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057437 name: Q8N250_HUMAN def: "cDNA FLJ33929 fis, clone CTONG2017458, moderately similar to Homo sapiens vascular Rab-GAP/TBC-containing protein" [UniProtKB:Q8N250] xref: EMBL:BAC03620.1 xref: UniProtKB:Q8N250 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057438 name: RHG24_HUMAN def: "Rho GTPase-activating protein 24" [UniProtKB:Q8N264] synonym: "Filamin-A-associated RhoGAP" EXACT [UniProtKB:Q8N264] synonym: "FilGAP" EXACT [UniProtKB:Q8N264] synonym: "p73RhoGAP" EXACT [UniProtKB:Q8N264] synonym: "RAC1- and CDC42-specific GTPase-activating protein of 72 kDa" EXACT [UniProtKB:Q8N264] synonym: "RC-GAP72" EXACT [UniProtKB:Q8N264] synonym: "Rho-type GTPase-activating protein 24" EXACT [UniProtKB:Q8N264] synonym: "RhoGAP of 73 kDa" EXACT [UniProtKB:Q8N264] synonym: "Sarcoma antigen NY-SAR-88" EXACT [UniProtKB:Q8N264] xref: EMBL:AAH47918.1 xref: EMBL:AAH98580.1 xref: EMBL:AAO65178.1 xref: EMBL:BAC03606.1 xref: EMBL:BAC85384.1 xref: EMBL:CAB66581.1 xref: UniProtKB:Q4KMG1 xref: UniProtKB:Q6ZNV3 xref: UniProtKB:Q86TI5 xref: UniProtKB:Q86WE4 xref: UniProtKB:Q8N264 xref: UniProtKB:Q9H0T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019724 ! ARHGAP24_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0015855 ! arhgap24-flna-6 physical interaction relationship: participates_in CCO:I0015990 ! arhgap24-flna-2 physical interaction relationship: participates_in CCO:I0016323 ! arhgap24-flna-3 physical interaction relationship: participates_in CCO:I0016324 ! arhgap24-flna-4 physical interaction relationship: participates_in CCO:I0017769 ! arhgap24-flna-1 physical interaction relationship: participates_in CCO:I0017770 ! arhgap24-cdc42-1 physical interaction relationship: participates_in CCO:I0017771 ! arhgap24-rac1-1 physical interaction relationship: participates_in CCO:I0018388 ! arhgap24-flna-5 colocalization relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069977 ! RHG24_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0069978 ! RHG24_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0069979 ! RHG24_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0069980 ! RHG24_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0069981 ! RHG24_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0069982 ! RHG24_HUMAN-Phosphothreonine452 [Term] id: CCO:B0057439 name: Q8N294_HUMAN def: "cDNA FLJ33633 fis, clone BRAMY2022786, highly similar to Homo sapiens dickkopf-3 (DKK-3) mRNA" [UniProtKB:Q8N294] xref: EMBL:BAC03555.1 xref: UniProtKB:Q8N294 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0057440 name: Q8N2B7_HUMAN xref: UniProtKB:Q8N2B7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057441 name: DEPD4_HUMAN def: "DEP domain-containing protein 4" [UniProtKB:Q8N2C3] xref: EMBL:AAH15117.1 xref: EMBL:AAI00930.1 xref: EMBL:BAC03525.1 xref: UniProtKB:Q496C8 xref: UniProtKB:Q8N2C3 xref: UniProtKB:Q96BW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017555 ! DEPDC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057442 name: Q8N2D3_HUMAN def: "Protein Wnt" [UniProtKB:Q8N2D3] xref: EMBL:BAC11683.1 xref: UniProtKB:Q8N2D3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0057443 name: ARM10_HUMAN def: "Armadillo repeat-containing protein 10" [UniProtKB:Q8N2F6] synonym: "Splicing variant involved in hepatocarcinogenesis protein" EXACT [UniProtKB:Q8N2F6] xref: EMBL:AAH03586.1 xref: EMBL:AAN72313.1 xref: EMBL:AAN72314.1 xref: EMBL:AAN72315.1 xref: EMBL:AAN72316.1 xref: EMBL:AAS07456.1 xref: EMBL:AAS07482.1 xref: EMBL:AAS07531.1 xref: EMBL:BAC11655.1 xref: EMBL:BAF84507.1 xref: UniProtKB:A8K703 xref: UniProtKB:Q75K91 xref: UniProtKB:Q75MG6 xref: UniProtKB:Q75ML8 xref: UniProtKB:Q8IZC1 xref: UniProtKB:Q8IZC2 xref: UniProtKB:Q8IZC3 xref: UniProtKB:Q8N2F6 xref: UniProtKB:Q9BTM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017043 ! ARMC10_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0063597 ! ARM10_HUMAN-Phosphoserine45 [Term] id: CCO:B0057444 name: ZN619_HUMAN def: "Zinc finger protein 619" [UniProtKB:Q8N2I2] xref: EMBL:BAC11495.1 xref: UniProtKB:Q8N2I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020859 ! ZNF619_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057445 name: Q8N2J5_HUMAN def: "cDNA FLJ90551 fis, clone OVARC1000779, weakly similar to ZINC FINGER PROTEIN 157" [UniProtKB:Q8N2J5] xref: EMBL:BAC11364.1 xref: UniProtKB:Q8N2J5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057446 name: NLGN1_HUMAN def: "Neuroligin-1 precursor" [UniProtKB:Q8N2Q7] xref: EMBL:AAH32555.1 xref: EMBL:BAA83022.2 xref: EMBL:BAC11039.1 xref: UniProtKB:Q8N2Q7 xref: UniProtKB:Q9UPT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018802 ! NLGN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005615 ! neurexin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation [Term] id: CCO:B0057447 name: OSR2_HUMAN def: "Protein odd-skipped-related 2" [UniProtKB:Q8N2R0] xref: EMBL:AAH16936.1 xref: EMBL:AAK74066.1 xref: EMBL:AAK74067.1 xref: EMBL:BAC11035.1 xref: UniProtKB:Q8N2R0 xref: UniProtKB:Q96AM6 xref: UniProtKB:Q96LB6 xref: UniProtKB:Q96LB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019242 ! OSR2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0057448 name: Q8N2R3_HUMAN def: "cDNA FLJ90033 fis, clone HEMBA1001621, highly similar to PROBABLE G PROTEIN-COUPLED RECEPTOR APJ" [UniProtKB:Q8N2R3] xref: EMBL:BAC11032.1 xref: UniProtKB:Q8N2R3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057449 name: LTBP4_HUMAN def: "Latent-transforming growth factor beta-binding protein 4 precursor" [UniProtKB:Q8N2S1] synonym: "LTBP-4" EXACT [UniProtKB:Q8N2S1] xref: EMBL:AAC39879.2 xref: EMBL:AAC39880.2 xref: EMBL:BAC11024.1 xref: EMBL:CAA73944.1 xref: UniProtKB:O00508 xref: UniProtKB:O75412 xref: UniProtKB:O75413 xref: UniProtKB:Q8N2S1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018530 ! LTBP4_human relationship: has_function CCO:F0001354 ! transforming growth factor beta receptor activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001663 ! glycosaminoglycan binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0007780 ! transforming growth factor beta binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001246 ! regulation of proteolysis relationship: participates_in CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:B0057450 name: AGGF1_HUMAN def: "Angiogenic factor with G patch and FHA domains 1" [UniProtKB:Q8N302] synonym: "Angiogenic factor VG5Q" EXACT [UniProtKB:Q8N302] synonym: "G patch domain-containing protein 7" EXACT [UniProtKB:Q8N302] synonym: "hVG5Q" EXACT [UniProtKB:Q8N302] synonym: "Vasculogenesis gene on 5q protein" EXACT [UniProtKB:Q8N302] xref: EMBL:AAB60856.1 xref: EMBL:AAH02828.1 xref: EMBL:AAH29382.2 xref: EMBL:AAR97615.1 xref: EMBL:AAR97617.1 xref: EMBL:BAA91519.1 xref: UniProtKB:O00581 xref: UniProtKB:Q53YS3 xref: UniProtKB:Q8N302 xref: UniProtKB:Q9BU84 xref: UniProtKB:Q9NW66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016930 ! AGGF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005863 ! eukaryotic cell surface binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0015509 ! aggf1-pldn physical interaction relationship: participates_in CCO:P0000506 ! positive regulation of endothelial cell proliferation [Term] id: CCO:B0057451 name: PGBD3_HUMAN def: "PiggyBac transposable element-derived protein 3" [UniProtKB:Q8N328] xref: EMBL:AAH28954.2 xref: EMBL:AAH34479.1 xref: EMBL:AAH63690.1 xref: EMBL:CAH70290.1 xref: UniProtKB:Q5W0M0 xref: UniProtKB:Q6PIH0 xref: UniProtKB:Q8N328 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019376 ! PGBD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000773 ! activation of JNKK activity relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis [Term] id: CCO:B0057452 name: MIER2_HUMAN def: "Mesoderm induction early response protein 2" [UniProtKB:Q8N344] synonym: "Mi-er2" EXACT [UniProtKB:Q8N344] xref: EMBL:AAH28203.2 xref: EMBL:BAA86507.2 xref: UniProtKB:Q8N344 xref: UniProtKB:Q9ULM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018621 ! MIER2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057453 name: OR2LD_HUMAN def: "Olfactory receptor 2L13" [UniProtKB:Q8N349] xref: EMBL:AAH28158.1 xref: EMBL:CAH70427.1 xref: UniProtKB:Q5VUR5 xref: UniProtKB:Q8N349 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019108 ! OR2L13_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057454 name: ZN786_HUMAN def: "Zinc finger protein 786" [UniProtKB:Q8N393] xref: EMBL:AAI28393.1 xref: EMBL:CAD39166.1 xref: UniProtKB:A1A568 xref: UniProtKB:Q8N393 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020939 ! ZNF786_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057455 name: PLCD3_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3" [UniProtKB:Q8N3E9] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q8N3E9] synonym: "Phosphoinositide phospholipase C delta-3" EXACT [UniProtKB:Q8N3E9] synonym: "Phospholipase C-delta-3" EXACT [UniProtKB:Q8N3E9] synonym: "PLC-delta-3" EXACT [UniProtKB:Q8N3E9] xref: EMBL:AAH10668.2 xref: EMBL:AAH72384.1 xref: EMBL:BAB85029.1 xref: EMBL:BAB85550.1 xref: EMBL:CAD39054.2 xref: UniProtKB:Q8N3E9 xref: UniProtKB:Q8TEC1 xref: UniProtKB:Q8TF37 xref: UniProtKB:Q96FL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019431 ! PLCD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069392 ! PLCD3_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0069393 ! PLCD3_HUMAN-Phosphoserine496 [Term] id: CCO:B0057456 name: ZN664_HUMAN def: "Zinc finger protein 664" [UniProtKB:Q8N3J9] synonym: "Zinc finger protein from organ of Corti" EXACT [UniProtKB:Q8N3J9] xref: EMBL:AAC41997.1 xref: EMBL:AAH51696.1 xref: EMBL:AAH93848.1 xref: EMBL:AAI01531.1 xref: EMBL:CAD38941.1 xref: EMBL:CAH10567.1 xref: UniProtKB:Q15914 xref: UniProtKB:Q3ZCQ7 xref: UniProtKB:Q8N3J9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020882 ! ZNF664_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057457 name: PHTF2_HUMAN def: "Putative homeodomain transcription factor 2" [UniProtKB:Q8N3S3] xref: EMBL:AAI27094.1 xref: EMBL:AAI27095.1 xref: EMBL:CAB66817.1 xref: EMBL:CAD38610.1 xref: EMBL:EAL24195.1 xref: EMBL:EAW77028.1 xref: UniProtKB:A0JP04 xref: UniProtKB:A0JP05 xref: UniProtKB:A4D1C2 xref: UniProtKB:Q8N3S3 xref: UniProtKB:Q9H099 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019388 ! PHTF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057458 name: LCORL_HUMAN def: "Ligand-dependent nuclear receptor corepressor-like protein" [UniProtKB:Q8N3X6] xref: EMBL:AAH37322.3 xref: EMBL:BAB70892.1 xref: EMBL:EAW92786.1 xref: UniProtKB:Q8N3X6 xref: UniProtKB:Q96NK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018463 ! LCORL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057459 name: LIRB2_HUMAN def: "Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor" [UniProtKB:Q8N423] synonym: "CD85 antigen-like family member D" EXACT [UniProtKB:Q8N423] synonym: "CD85d antigen" EXACT [UniProtKB:Q8N423] synonym: "ILT-4" EXACT [UniProtKB:Q8N423] synonym: "Immunoglobulin-like transcript 4" EXACT [UniProtKB:Q8N423] synonym: "Leukocyte immunoglobulin-like receptor 2" EXACT [UniProtKB:Q8N423] synonym: "LIR-2" EXACT [UniProtKB:Q8N423] synonym: "MIR-10" EXACT [UniProtKB:Q8N423] synonym: "Monocyte/macrophage immunoglobulin-like receptor 10" EXACT [UniProtKB:Q8N423] xref: EMBL:AAB87662.1 xref: EMBL:AAH36827.1 xref: EMBL:AAL36990.1 xref: EMBL:AAL36991.1 xref: UniProtKB:O75017 xref: UniProtKB:Q8N423 xref: UniProtKB:Q8NHJ7 xref: UniProtKB:Q8NHJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018498 ! LILRB2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0057460 name: RGF1C_HUMAN def: "Ras-GEF domain-containing family member 1C" [UniProtKB:Q8N431] xref: EMBL:AAH36802.1 xref: EMBL:AAP97676.1 xref: EMBL:BAC04079.1 xref: EMBL:EAW53769.1 xref: UniProtKB:Q7Z4T0 xref: UniProtKB:Q8N431 xref: UniProtKB:Q8NA49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019693 ! RASGEF1C_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057461 name: Q8N437_HUMAN def: "RASGEF1B protein" [UniProtKB:Q8N437] xref: EMBL:AAH36784.1 xref: UniProtKB:Q8N437 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019692 ! RASGEF1B_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057462 name: FGRL1_HUMAN def: "Fibroblast growth factor receptor-like 1 precursor" [UniProtKB:Q8N441] synonym: "FGF homologous factor receptor" EXACT [UniProtKB:Q8N441] synonym: "FGF receptor-like protein 1" EXACT [UniProtKB:Q8N441] synonym: "FGFR-like protein" EXACT [UniProtKB:Q8N441] synonym: "Fibroblast growth factor receptor 5" EXACT [UniProtKB:Q8N441] xref: EMBL:AAH13955.2 xref: EMBL:AAH36769.1 xref: EMBL:AAK15273.1 xref: EMBL:AAK26742.1 xref: EMBL:AAQ88670.1 xref: EMBL:CAC14171.1 xref: UniProtKB:Q6PJN1 xref: UniProtKB:Q8N441 xref: UniProtKB:Q9BXN7 xref: UniProtKB:Q9H4D7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017804 ! FGFRL1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001344 ! fibroblast growth factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0057463 name: GUF1_HUMAN def: "GTP-binding protein GUF1 homolog" [UniProtKB:Q8N442] xref: EMBL:AAH36768.1 xref: EMBL:BAB14507.1 xref: EMBL:BAB15090.1 xref: UniProtKB:Q5XKM8 xref: UniProtKB:Q8N442 xref: UniProtKB:Q9H710 xref: UniProtKB:Q9H8U4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018094 ! GUF1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057464 name: SFRP1_HUMAN def: "Secreted frizzled-related protein 1 precursor" [UniProtKB:Q8N474] synonym: "Frizzled-related protein 1" EXACT [UniProtKB:Q8N474] synonym: "FRP-1" EXACT [UniProtKB:Q8N474] synonym: "SARP-2" EXACT [UniProtKB:Q8N474] synonym: "Secreted apoptosis-related protein 2" EXACT [UniProtKB:Q8N474] synonym: "sFRP-1" EXACT [UniProtKB:Q8N474] xref: EMBL:AAB61576.1 xref: EMBL:AAB70793.1 xref: EMBL:AAC12877.1 xref: EMBL:AAH36503.1 xref: UniProtKB:O00546 xref: UniProtKB:O14779 xref: UniProtKB:Q8N474 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019873 ! SFRP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0057465 name: RYBP_HUMAN def: "RING1 and YY1-binding protein" [UniProtKB:Q8N488] synonym: "APAP-1" EXACT [UniProtKB:Q8N488] synonym: "Apoptin-associating protein 1" EXACT [UniProtKB:Q8N488] synonym: "Death effector domain-associated factor" EXACT [UniProtKB:Q8N488] synonym: "DED-associated factor" EXACT [UniProtKB:Q8N488] synonym: "YY1 and E4TF1-associated factor 1" EXACT [UniProtKB:Q8N488] xref: EMBL:AAD51858.1 xref: EMBL:AAH14959.1 xref: EMBL:AAH36459.1 xref: EMBL:AAK63197.1 xref: EMBL:AAO73587.1 xref: EMBL:BAA89486.1 xref: UniProtKB:Q8N488 xref: UniProtKB:Q9P2W5 xref: UniProtKB:Q9UMW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019816 ! RYBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015833 ! ring1-rybp physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070269 ! RYBP_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0070270 ! RYBP_HUMAN-Phosphoserine130 [Term] id: CCO:B0057466 name: ARL14_HUMAN def: "ADP-ribosylation factor-like protein 14" [UniProtKB:Q8N4G2] synonym: "ADP-ribosylation factor 7" EXACT [UniProtKB:Q8N4G2] xref: EMBL:AAH34354.1 xref: EMBL:BAB15411.1 xref: UniProtKB:Q8N4G2 xref: UniProtKB:Q9H655 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017034 ! ARL14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0063596 ! ARL14_HUMAN-Phosphotyrosine31 [Term] id: CCO:B0057467 name: CI100_HUMAN def: "Vav-like protein C9orf100" [UniProtKB:Q8N4T4] xref: EMBL:AAH33666.1 xref: EMBL:AAH38673.1 xref: EMBL:AAR01010.1 xref: EMBL:AAR01011.1 xref: EMBL:BAB55192.1 xref: EMBL:CAI13452.1 xref: UniProtKB:Q49AG0 xref: UniProtKB:Q6TPQ2 xref: UniProtKB:Q8N4T4 xref: UniProtKB:Q96ST6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017360 ! C9orf100_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015181 ! c9orf100-dvl2 physical interaction relationship: participates_in CCO:I0015252 ! c9orf100-rbpms physical interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0057468 name: RAB42_HUMAN def: "Putative Ras-related protein Rab-42" [UniProtKB:Q8N4Z0] xref: EMBL:AAH33175.1 xref: EMBL:CAI22290.1 xref: UniProtKB:Q8N4Z0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019598 ! RAB42_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069686 ! RAB42_HUMAN-Cysteine methyl ester105 [Term] id: CCO:B0057469 name: Q8N537_HUMAN def: "LGR4 protein" [UniProtKB:Q8N537] xref: EMBL:AAH33039.1 xref: UniProtKB:Q8N537 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018481 ! LGR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057470 name: ZN276_HUMAN def: "Zinc finger protein 276" [UniProtKB:Q8N554] synonym: "Zfp-276" EXACT [UniProtKB:Q8N554] xref: EMBL:AAH32781.2 xref: EMBL:AAI07604.1 xref: EMBL:AAI10349.1 xref: EMBL:AAI11409.1 xref: EMBL:AAQ15128.1 xref: EMBL:AAQ15129.1 xref: UniProtKB:Q0VGA1 xref: UniProtKB:Q2TBE8 xref: UniProtKB:Q3B7H7 xref: UniProtKB:Q8N554 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020690 ! ZNF276_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015646 ! q96br9-zfp276 physical interaction relationship: participates_in CCO:I0019013 ! atxn1-zfp276 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072082 ! ZN276_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0072083 ! ZN276_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0072084 ! ZN276_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0072085 ! ZN276_HUMAN-Phosphoserine360 [Term] id: CCO:B0057471 name: ZN561_HUMAN def: "Zinc finger protein 561" [UniProtKB:Q8N587] xref: EMBL:AAH12144.1 xref: EMBL:AAH32668.1 xref: UniProtKB:Q6PJS0 xref: UniProtKB:Q8N587 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020820 ! ZNF561_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057472 name: Q8N5H0_HUMAN def: "Phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III" [UniProtKB:Q8N5H0] synonym: "Phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III, isoform CRA_b" EXACT [UniProtKB:Q8N5H0] xref: EMBL:AAH32389.1 xref: EMBL:EAW70445.1 xref: UniProtKB:Q8N5H0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017851 ! PIP5K3_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057473 name: Q8N5H6_HUMAN def: "YEATS2 protein" [UniProtKB:Q8N5H6] xref: EMBL:AAH32368.1 xref: UniProtKB:Q8N5H6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020513 ! YEATS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057474 name: SH2D3_HUMAN def: "SH2 domain-containing protein 3C" [UniProtKB:Q8N5H7] synonym: "Novel SH2-containing protein 3" EXACT [UniProtKB:Q8N5H7] xref: EMBL:AAD28246.1 xref: EMBL:AAH27962.1 xref: EMBL:AAH32365.1 xref: EMBL:AAQ88456.1 xref: EMBL:AAQ89948.1 xref: EMBL:CAI39763.1 xref: EMBL:CAI39766.1 xref: EMBL:CAI41179.1 xref: EMBL:CAI41182.1 xref: EMBL:CAI46101.1 xref: UniProtKB:Q5HYE5 xref: UniProtKB:Q6UY42 xref: UniProtKB:Q8N5H7 xref: UniProtKB:Q8N6X3 xref: UniProtKB:Q9Y2X5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019889 ! SH2D3C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0070470 ! SH2D3_HUMAN-Phosphotyrosine183 relationship: transforms_into CCO:B0070471 ! SH2D3_HUMAN-Phosphotyrosine278 relationship: transforms_into CCO:B0070472 ! SH2D3_HUMAN-Phosphotyrosine283 relationship: transforms_into CCO:B0070473 ! SH2D3_HUMAN-Phosphotyrosine793 [Term] id: CCO:B0057475 name: SPIC_HUMAN def: "Transcription factor Spi-C" [UniProtKB:Q8N5J4] xref: EMBL:AAH32317.1 xref: EMBL:AAN84476.1 xref: UniProtKB:Q8N5J4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020016 ! SPIC_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057476 name: Q8N5K7_HUMAN def: "ZNF44 protein" [UniProtKB:Q8N5K7] synonym: "Zinc finger protein 44 (KOX 7), isoform CRA_a" EXACT [UniProtKB:Q8N5K7] xref: EMBL:AAH32246.1 xref: EMBL:EAW84266.1 xref: UniProtKB:Q8N5K7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020976 ! ZNF44_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057477 name: Q8N5M2_HUMAN def: "PLXNA2 protein" [UniProtKB:Q8N5M2] xref: EMBL:AAH32125.1 xref: EMBL:AAH94835.1 xref: UniProtKB:Q8N5M2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019447 ! PLXNA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057478 name: TBC19_HUMAN def: "TBC1 domain family member 19" [UniProtKB:Q8N5T2] xref: EMBL:AAH31642.1 xref: EMBL:BAA91992.1 xref: UniProtKB:Q8N5T2 xref: UniProtKB:Q9NUX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020162 ! TBC1D19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071215 ! TBC19_HUMAN-Phosphotyrosine25 [Term] id: CCO:B0057479 name: M4A15_HUMAN def: "Membrane-spanning 4-domains subfamily A member 15" [UniProtKB:Q8N5U1] xref: EMBL:AAH31610.1 xref: EMBL:EAW73898.1 xref: UniProtKB:Q8N5U1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018544 ! MS4A15_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057480 name: NGEF_HUMAN def: "Ephexin-1" [UniProtKB:Q8N5V2] synonym: "Eph-interacting exchange protein" EXACT [UniProtKB:Q8N5V2] synonym: "Neuronal guanine nucleotide exchange factor" EXACT [UniProtKB:Q8N5V2] xref: EMBL:AAH31573.1 xref: EMBL:AAH73962.1 xref: EMBL:AAX93288.1 xref: EMBL:AAY24359.1 xref: EMBL:CAC00686.1 xref: UniProtKB:Q53QQ4 xref: UniProtKB:Q53ST7 xref: UniProtKB:Q6GMQ5 xref: UniProtKB:Q8N5V2 xref: UniProtKB:Q9NQD6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018784 ! NGEF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0068704 ! NGEF_HUMAN-Phosphotyrosine179 relationship: transforms_into CCO:B0068705 ! NGEF_HUMAN-Phosphoserine606 [Term] id: CCO:B0057481 name: IF4E3_HUMAN def: "Eukaryotic translation initiation factor 4E type 3" [UniProtKB:Q8N5X7] synonym: "eIF-4E type 3" EXACT [UniProtKB:Q8N5X7] synonym: "eIF-4E3" EXACT [UniProtKB:Q8N5X7] synonym: "eIF4E type 3" EXACT [UniProtKB:Q8N5X7] synonym: "eIF4E-3" EXACT [UniProtKB:Q8N5X7] xref: EMBL:AAH31289.3 xref: EMBL:AAH68443.1 xref: UniProtKB:Q6NUT1 xref: UniProtKB:Q8N5X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018228 ! EIF4E3_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0057482 name: MS3L1_HUMAN def: "Male-specific lethal-3 protein-like 1" [UniProtKB:Q8N5Y2] synonym: "Male-specific lethal-3 homolog 1" EXACT [UniProtKB:Q8N5Y2] synonym: "MSL3-like 1" EXACT [UniProtKB:Q8N5Y2] xref: EMBL:AAD38499.1 xref: EMBL:AAH31210.1 xref: EMBL:CAB43308.1 xref: EMBL:CAD28473.1 xref: UniProtKB:Q8N5Y2 xref: UniProtKB:Q9UG70 xref: UniProtKB:Q9Y5Z8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018661 ! MSL3L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068292 ! MS3L1_HUMAN-Phosphoserine367 relationship: transforms_into CCO:B0068293 ! MS3L1_HUMAN-Phosphoserine400 relationship: transforms_into CCO:B0068294 ! MS3L1_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0068295 ! MS3L1_HUMAN-Phosphoserine411 [Term] id: CCO:B0057483 name: OR2C3_HUMAN def: "Olfactory receptor 2C3" [UniProtKB:Q8N628] xref: EMBL:AAH30717.1 xref: EMBL:BAC05875.1 xref: EMBL:CAI17147.2 xref: UniProtKB:Q5JQS4 xref: UniProtKB:Q8N628 xref: UniProtKB:Q8NGW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019090 ! OR2C3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057484 name: ZBTB2_HUMAN def: "Zinc finger and BTB domain-containing protein 2" [UniProtKB:Q8N680] xref: EMBL:AAH20172.1 xref: EMBL:BAA96007.1 xref: EMBL:CAI13589.1 xref: UniProtKB:Q5SZ81 xref: UniProtKB:Q8N680 xref: UniProtKB:Q9P245 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020567 ! ZBTB2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071984 ! ZBTB2_HUMAN-Phosphoserine435 [Term] id: CCO:B0057485 name: ESX1_HUMAN def: "Homeobox protein ESX1" [UniProtKB:Q8N693] synonym: "Extraembryonic, spermatogenesis, homeobox 1" EXACT [UniProtKB:Q8N693] xref: EMBL:AAH42633.1 xref: EMBL:AAH53599.1 xref: EMBL:AAM62141.1 xref: UniProtKB:Q7Z6K7 xref: UniProtKB:Q8N693 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017732 ! ESX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057486 name: IGSF1_HUMAN def: "Immunoglobulin superfamily member 1 precursor" [UniProtKB:Q8N6C5] synonym: "Immunoglobulin-like domain-containing protein 1" EXACT [UniProtKB:Q8N6C5] synonym: "InhBP" EXACT [UniProtKB:Q8N6C5] synonym: "Inhibin-binding protein" EXACT [UniProtKB:Q8N6C5] synonym: "p120" EXACT [UniProtKB:Q8N6C5] synonym: "Pituitary gland specific factor 2" EXACT [UniProtKB:Q8N6C5] xref: EMBL:AAC52057.1 xref: EMBL:BAA20819.2 xref: EMBL:BAB40235.1 xref: EMBL:CAA71535.1 xref: EMBL:CAB70713.1 xref: UniProtKB:O15070 xref: UniProtKB:Q8N6C5 xref: UniProtKB:Q9NTC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018239 ! IGSF1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007320 ! inhibin beta-A binding relationship: has_function CCO:F0007321 ! inhibin beta-B binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057487 name: LIRA3_HUMAN def: "Leukocyte immunoglobulin-like receptor subfamily A member 3 precursor" [UniProtKB:Q8N6C8] synonym: "CD85 antigen-like family member E" EXACT [UniProtKB:Q8N6C8] synonym: "CD85e antigen" EXACT [UniProtKB:Q8N6C8] synonym: "ILT-6" EXACT [UniProtKB:Q8N6C8] synonym: "Immunoglobulin-like transcript 6" EXACT [UniProtKB:Q8N6C8] synonym: "Leukocyte immunoglobulin-like receptor 4" EXACT [UniProtKB:Q8N6C8] synonym: "LIR-4" EXACT [UniProtKB:Q8N6C8] synonym: "Monocyte inhibitory receptor HM43/HM31" EXACT [UniProtKB:Q8N6C8] xref: EMBL:AAB68666.1 xref: EMBL:AAB68667.1 xref: EMBL:AAB87661.1 xref: EMBL:AAH28208.1 xref: EMBL:AAM18035.1 xref: EMBL:AAM18036.1 xref: EMBL:AAM18037.1 xref: EMBL:AAM18038.1 xref: EMBL:AAM18039.1 xref: EMBL:AAM18040.1 xref: EMBL:AAM18041.1 xref: EMBL:AAM18042.1 xref: UniProtKB:O15469 xref: UniProtKB:O15470 xref: UniProtKB:O75016 xref: UniProtKB:Q8N151 xref: UniProtKB:Q8N154 xref: UniProtKB:Q8N6C8 xref: UniProtKB:Q8NHJ1 xref: UniProtKB:Q8NHJ2 xref: UniProtKB:Q8NHJ3 xref: UniProtKB:Q8NHJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018497 ! LILRA3_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0015525 ! ewsr1-lilra3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057488 name: Q8N6F6_HUMAN xref: UniProtKB:Q8N6F6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057489 name: ARFG2_HUMAN def: "ADP-ribosylation factor GTPase-activating protein 2" [UniProtKB:Q8N6H7] synonym: "ARF GAP 2" EXACT [UniProtKB:Q8N6H7] synonym: "GTPase-activating protein ZNF289" EXACT [UniProtKB:Q8N6H7] synonym: "Zinc finger protein 289" EXACT [UniProtKB:Q8N6H7] xref: EMBL:AAH30148.1 xref: EMBL:BAB55144.1 xref: EMBL:BAE45716.1 xref: EMBL:CAD39004.1 xref: UniProtKB:Q3LIF2 xref: UniProtKB:Q8N3I1 xref: UniProtKB:Q8N6H7 xref: UniProtKB:Q96SX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017008 ! ARFGAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0065700 ! ARFG2_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0065701 ! ARFG2_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0065702 ! ARFG2_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0065703 ! ARFG2_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0065704 ! ARFG2_HUMAN-Phosphoserine498 [Term] id: CCO:B0057490 name: EID2_HUMAN def: "EP300-interacting inhibitor of differentiation 2" [UniProtKB:Q8N6I1] synonym: "CREBBP/EP300 inhibitor 2" EXACT [UniProtKB:Q8N6I1] synonym: "EID-1-like inhibitor of differentiation 2" EXACT [UniProtKB:Q8N6I1] synonym: "EID-2" EXACT [UniProtKB:Q8N6I1] xref: EMBL:AAH30137.3 xref: EMBL:AAH99899.1 xref: EMBL:AAP12559.1 xref: EMBL:BAC87454.1 xref: EMBL:EAW56909.1 xref: UniProtKB:A7YQ71 xref: UniProtKB:Q6X7T0 xref: UniProtKB:Q6ZR61 xref: UniProtKB:Q8N6I1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017674 ! EID2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000721 ! transforming growth factor beta receptor complex assembly relationship: participates_in CCO:P0000723 ! SMAD protein complex assembly relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001273 ! negative regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0057491 name: Q8N6P3_HUMAN def: "ANGPT1 protein" [UniProtKB:Q8N6P3] xref: EMBL:AAH29406.1 xref: UniProtKB:Q8N6P3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057492 name: SIRT6_HUMAN def: "Mono-ADP-ribosyltransferase sirtuin-6" [UniProtKB:Q8N6T7] synonym: "EC 2.4.2.31" EXACT [UniProtKB:Q8N6T7] synonym: "SIR2-like protein 6" EXACT [UniProtKB:Q8N6T7] xref: EMBL:AAC34468.1 xref: EMBL:AAD15478.1 xref: EMBL:AAF43432.1 xref: EMBL:AAH00090.1 xref: EMBL:AAH04218.1 xref: EMBL:AAH05026.1 xref: EMBL:AAH28220.1 xref: EMBL:BAC11222.1 xref: EMBL:CAG33481.1 xref: UniProtKB:O75291 xref: UniProtKB:Q6IAF5 xref: UniProtKB:Q6PK99 xref: UniProtKB:Q8N6T7 xref: UniProtKB:Q8NCD2 xref: UniProtKB:Q9BSI5 xref: UniProtKB:Q9BWP3 xref: UniProtKB:Q9NRC7 xref: UniProtKB:Q9UQD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019916 ! SIRT6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015355 ! elf5-sirt6 physical interaction relationship: participates_in CCO:I0019623 ! sirt6-chd3 physical interaction relationship: participates_in CCO:I0019835 ! sirt6-vim physical interaction relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070548 ! SIRT6_HUMAN-Phosphothreonine294 relationship: transforms_into CCO:B0070549 ! SIRT6_HUMAN-Phosphoserine303 [Term] id: CCO:B0057493 name: Q8N6U1_HUMAN def: "PER1 protein" [UniProtKB:Q8N6U1] synonym: "Period homolog 1 (Drosophila), isoform CRA_b" EXACT [UniProtKB:Q8N6U1] xref: EMBL:AAH28207.1 xref: EMBL:EAW90089.1 xref: UniProtKB:Q8N6U1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019366 ! PER1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057494 name: GP161_HUMAN def: "Probable G-protein coupled receptor 161" [UniProtKB:Q8N6U8] synonym: "G-protein coupled receptor RE2" EXACT [UniProtKB:Q8N6U8] xref: EMBL:AAC61598.1 xref: EMBL:AAH28163.1 xref: EMBL:AAP32300.1 xref: EMBL:BAG51611.1 xref: EMBL:CAI22622.1 xref: EMBL:CAI22623.1 xref: UniProtKB:O75963 xref: UniProtKB:Q5TGK0 xref: UniProtKB:Q5TGK1 xref: UniProtKB:Q5TGK2 xref: UniProtKB:Q8N6U8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017983 ! GPR161_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057495 name: Q8N6X9_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q8N6X9] xref: EMBL:AAH27922.1 xref: UniProtKB:Q8N6X9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057496 name: Q8N717_HUMAN def: "KLF4 protein" [UniProtKB:Q8N717] synonym: "Kruppel-like factor 4 (Gut)" EXACT [UniProtKB:Q8N717] xref: EMBL:AAH30811.1 xref: EMBL:CAI12255.1 xref: UniProtKB:Q8N717 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018419 ! KLF4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0057497 name: NPW_HUMAN def: "Neuropeptide W precursor" [UniProtKB:Q8N729] synonym: "hPPL8" EXACT [UniProtKB:Q8N729] synonym: "Preproprotein L8" EXACT [UniProtKB:Q8N729] xref: EMBL:BAC07172.1 xref: UniProtKB:Q8N729 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018841 ! NPW_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057498 name: KC1AL_HUMAN def: "Casein kinase I isoform alpha-like" [UniProtKB:Q8N752] synonym: "CK1" EXACT [UniProtKB:Q8N752] synonym: "CKI-alpha-like" EXACT [UniProtKB:Q8N752] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q8N752] xref: EMBL:AAH28723.1 xref: EMBL:CAI15195.1 xref: EMBL:EAX08587.1 xref: UniProtKB:Q5T2N2 xref: UniProtKB:Q8N752 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018378 ! CSNK1A1L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0057499 name: ZN525_HUMAN def: "Zinc finger protein 525" [UniProtKB:Q8N782] xref: EMBL:BAB85565.1 xref: EMBL:BAC05417.1 xref: UniProtKB:Q8N782 xref: UniProtKB:Q8TF23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020796 ! ZNF525_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057500 name: Q8N798_HUMAN def: "cDNA FLJ25878 fis, clone CBR02538" [UniProtKB:Q8N798] xref: EMBL:BAC05401.1 xref: UniProtKB:Q8N798 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057501 name: Q8N7B4_HUMAN def: "CDNA FLJ25829 fis, clone TST08126" [UniProtKB:Q8N7B4] xref: EMBL:BAC05383.1 xref: UniProtKB:Q8N7B4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057502 name: PAF1_HUMAN def: "RNA polymerase II-associated factor 1 homolog" [UniProtKB:Q8N7H5] synonym: "hPAF1" EXACT [UniProtKB:Q8N7H5] synonym: "Pancreatic differentiation protein 2" EXACT [UniProtKB:Q8N7H5] xref: EMBL:AAC25503.1 xref: EMBL:AAH00017.1 xref: EMBL:AAH13402.1 xref: EMBL:BAA92020.1 xref: EMBL:BAC05305.1 xref: EMBL:CAC20564.1 xref: EMBL:EAW56880.1 xref: EMBL:EAW56881.1 xref: UniProtKB:O75239 xref: UniProtKB:Q8N7H5 xref: UniProtKB:Q9H166 xref: UniProtKB:Q9NUU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019288 ! PAF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069051 ! PAF1_HUMAN-Phosphoserine456 relationship: transforms_into CCO:B0069052 ! PAF1_HUMAN-Phosphoserine460 relationship: transforms_into CCO:B0069053 ! PAF1_HUMAN-Phosphoserine466 [Term] id: CCO:B0057503 name: ZN433_HUMAN def: "Zinc finger protein 433" [UniProtKB:Q8N7K0] xref: EMBL:AAH47412.1 xref: EMBL:BAC05279.1 xref: EMBL:EAW84254.1 xref: UniProtKB:Q86VX3 xref: UniProtKB:Q8N7K0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020747 ! ZNF433_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057504 name: ZN283_HUMAN def: "Zinc finger protein 283" [UniProtKB:Q8N7M2] xref: EMBL:AAO45833.1 xref: EMBL:BAC05251.1 xref: EMBL:BAG57956.1 xref: UniProtKB:B4DGZ5 xref: UniProtKB:Q86WM6 xref: UniProtKB:Q8N7M2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020693 ! ZNF283_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057505 name: ZN676_HUMAN def: "Zinc finger protein 676" [UniProtKB:Q8N7Q3] xref: EMBL:BAC05174.1 xref: UniProtKB:A8MVX5 xref: UniProtKB:Q8N7Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020891 ! ZNF676_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057506 name: NANG2_HUMAN def: "Putative homeobox protein NANOG2" [UniProtKB:Q8N7R0] xref: EMBL:AAS57555.1 xref: EMBL:BAC05167.1 xref: UniProtKB:Q8N7R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018714 ! NANOGP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057507 name: Q8N7S5_HUMAN def: "cDNA FLJ40406 fis, clone TESTI2037534, weakly similar to 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11)" [UniProtKB:Q8N7S5] xref: EMBL:BAC05152.1 xref: UniProtKB:Q8N7S5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057508 name: TPRX1_HUMAN def: "Tetra-peptide repeat homeobox protein 1" [UniProtKB:Q8N7U7] xref: EMBL:AAI41864.1 xref: EMBL:BAC05130.1 xref: UniProtKB:A5D8Y3 xref: UniProtKB:Q8N7U7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020333 ! TPRX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057509 name: Q8N7X7_HUMAN def: "cDNA FLJ40236 fis, clone TESTI2023214, weakly similar to 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11)" [UniProtKB:Q8N7X7] xref: EMBL:BAC05099.1 xref: UniProtKB:Q8N7X7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057510 name: ZN611_HUMAN def: "Zinc finger protein 611" [UniProtKB:Q8N823] xref: EMBL:BAC05052.1 xref: EMBL:CAH10596.1 xref: UniProtKB:Q69YG9 xref: UniProtKB:Q8N823 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020853 ! ZNF611_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057511 name: ZN713_HUMAN def: "Zinc finger protein 713" [UniProtKB:Q8N859] xref: EMBL:BAC04991.1 xref: UniProtKB:Q8N859 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020915 ! ZNF713_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057512 name: ZN614_HUMAN def: "Zinc finger protein 614" [UniProtKB:Q8N883] xref: EMBL:AAH22246.1 xref: EMBL:AAI01393.1 xref: EMBL:AAI01394.1 xref: EMBL:AAI01395.1 xref: EMBL:AAI01396.1 xref: EMBL:BAC04966.1 xref: UniProtKB:Q494T8 xref: UniProtKB:Q8N883 xref: UniProtKB:Q8TCF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020855 ! ZNF614_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057513 name: Q8N886_HUMAN xref: UniProtKB:Q8N886 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057514 name: ZN366_HUMAN def: "Zinc finger protein 366" [UniProtKB:Q8N895] xref: EMBL:BAC04954.1 xref: EMBL:DAA00066.1 xref: UniProtKB:Q7RTV4 xref: UniProtKB:Q8N895 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020720 ! ZNF366_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057515 name: TFSC1_HUMAN def: "TFIIS central domain-containing protein 1" [UniProtKB:Q8N8B7] xref: EMBL:BAC04930.1 xref: UniProtKB:A6NI06 xref: UniProtKB:Q8N8B7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017626 ! q8n8b7-atxn1 physical interaction relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0057516 name: ZN781_HUMAN def: "Zinc finger protein 781" [UniProtKB:Q8N8C0] xref: EMBL:AAI08688.1 xref: EMBL:BAC04927.1 xref: UniProtKB:Q2VPJ8 xref: UniProtKB:Q8N8C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020935 ! ZNF781_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057517 name: PDCD7_HUMAN def: "Programmed cell death protein 7" [UniProtKB:Q8N8D1] synonym: "ES18" EXACT [UniProtKB:Q8N8D1] synonym: "HES18" EXACT [UniProtKB:Q8N8D1] xref: EMBL:AAD20241.1 xref: EMBL:AAH16992.2 xref: EMBL:AAP36059.1 xref: EMBL:BAC04915.1 xref: UniProtKB:Q8N8D1 xref: UniProtKB:Q96AK8 xref: UniProtKB:Q9Y6D7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019329 ! PDCD7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000291 ! U12-dependent spliceosome relationship: participates_in CCO:I0020098 ! pdcd7-fez1 physical interaction relationship: participates_in CCO:I0020099 ! pdcd7-hap1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0057518 name: Q8N8F5_HUMAN def: "cDNA FLJ39577 fis, clone SKMUS2002920, weakly similar to Homo sapiens ASB-1 protein mRNA" [UniProtKB:Q8N8F5] xref: EMBL:BAC04888.1 xref: UniProtKB:Q8N8F5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057519 name: VGLL2_HUMAN def: "Transcription cofactor vestigial-like protein 2" [UniProtKB:Q8N8G2] synonym: "Protein VITO1" EXACT [UniProtKB:Q8N8G2] synonym: "Vgl-2" EXACT [UniProtKB:Q8N8G2] xref: EMBL:AAH69316.1 xref: EMBL:AAI00799.1 xref: EMBL:AAI00800.1 xref: EMBL:AAI18546.1 xref: EMBL:AAI18623.1 xref: EMBL:AAL17720.1 xref: EMBL:BAC04881.1 xref: EMBL:CAE17331.1 xref: EMBL:CAI42376.1 xref: EMBL:EAW48211.1 xref: UniProtKB:Q8N8G2 xref: UniProtKB:Q8WWX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020446 ! VGLL2_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057520 name: ZN321_HUMAN def: "KRAB domain-containing protein ZNF321" [UniProtKB:Q8N8H1] xref: EMBL:AAH46449.2 xref: EMBL:AAI19628.1 xref: EMBL:AAI19629.1 xref: EMBL:BAC04871.1 xref: EMBL:CAH18080.1 xref: UniProtKB:Q68DZ0 xref: UniProtKB:Q86SS5 xref: UniProtKB:Q8N8H1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020703 ! ZNF321_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057521 name: PI4P1_HUMAN def: "Putative phosphatidylinositol 4-kinase alpha-like protein P1" [UniProtKB:Q8N8J0] xref: EMBL:AAH72398.1 xref: EMBL:BAC04851.1 xref: EMBL:BAF85384.1 xref: UniProtKB:Q8N8J0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019395 ! PI4KAP1_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:B0057522 name: ZN615_HUMAN def: "Zinc finger protein 615" [UniProtKB:Q8N8J6] xref: EMBL:AAI05101.1 xref: EMBL:AAI05103.1 xref: EMBL:BAC04843.1 xref: EMBL:BAC87399.1 xref: EMBL:BAD18638.1 xref: EMBL:CAI56755.1 xref: UniProtKB:Q2M2Y6 xref: UniProtKB:Q5CZB0 xref: UniProtKB:Q6ZMT7 xref: UniProtKB:Q6ZRB3 xref: UniProtKB:Q8N8J6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020856 ! ZNF615_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072184 ! ZN615_HUMAN-Phosphoserine79 [Term] id: CCO:B0057523 name: ZN491_HUMAN def: "Zinc finger protein 491" [UniProtKB:Q8N8L2] xref: EMBL:AAI01591.1 xref: EMBL:AAI01593.1 xref: EMBL:BAC03809.1 xref: EMBL:BAC04824.1 xref: UniProtKB:Q3MJ35 xref: UniProtKB:Q8N8L2 xref: UniProtKB:Q8NAT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020775 ! ZNF491_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057524 name: ARL10_HUMAN def: "ADP-ribosylation factor-like protein 10" [UniProtKB:Q8N8L6] xref: EMBL:BAC04820.1 xref: EMBL:DAA02136.1 xref: UniProtKB:Q8N8L6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017032 ! ARL10_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057525 name: Q8N8P1_HUMAN xref: UniProtKB:Q8N8P1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057526 name: BMPER_HUMAN def: "BMP-binding endothelial regulator protein precursor" [UniProtKB:Q8N8U9] synonym: "Bone morphogenetic protein-binding endothelial cell precursor-derived regulator" EXACT [UniProtKB:Q8N8U9] synonym: "hCV2" EXACT [UniProtKB:Q8N8U9] synonym: "Protein crossveinless-2" EXACT [UniProtKB:Q8N8U9] xref: EMBL:AAH60868.1 xref: EMBL:AAP89012.1 xref: EMBL:BAB85551.1 xref: EMBL:BAC04712.1 xref: UniProtKB:Q8N8U9 xref: UniProtKB:Q8TF36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017168 ! BMPER_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway [Term] id: CCO:B0057527 name: Q8N8Y4_HUMAN def: "cDNA FLJ38706 fis, clone KIDNE2002795, moderately similar to ZINC FINGER PROTEIN 7" [UniProtKB:Q8N8Y4] synonym: "Zinc finger protein 7 (KOX 4, clone HF.16), isoform CRA_c" EXACT [UniProtKB:Q8N8Y4] xref: EMBL:BAC04677.1 xref: EMBL:EAW82040.1 xref: UniProtKB:Q8N8Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005969 ! ZNF7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057528 name: ZFP41_HUMAN def: "Zinc finger protein 41 homolog" [UniProtKB:Q8N8Y5] synonym: "Zfp-41" EXACT [UniProtKB:Q8N8Y5] xref: EMBL:AAH34608.1 xref: EMBL:BAC04676.1 xref: UniProtKB:Q8N8Y5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020591 ! ZFP41_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057529 name: ZN441_HUMAN def: "Zinc finger protein 441" [UniProtKB:Q8N8Z8] xref: EMBL:BAC04661.1 xref: UniProtKB:Q8N8Z8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020753 ! ZNF441_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057530 name: Q8N929_HUMAN def: "cDNA FLJ38465 fis, clone FEBRA2021497" [UniProtKB:Q8N929] xref: EMBL:BAC04627.1 xref: UniProtKB:Q8N929 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057531 name: Q8N950_HUMAN xref: UniProtKB:Q8N950 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003205 ! transcription activator activity relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0057532 name: ABTB2_HUMAN def: "Ankyrin repeat and BTB/POZ domain-containing protein 2" [UniProtKB:Q8N961] xref: EMBL:AAH93968.1 xref: EMBL:BAC03697.1 xref: EMBL:BAC04595.1 xref: EMBL:CAE45913.3 xref: UniProtKB:Q52LD6 xref: UniProtKB:Q6MZW4 xref: UniProtKB:Q8N961 xref: UniProtKB:Q8NB44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016878 ! ABTB2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0057533 name: ZN709_HUMAN def: "Zinc finger protein 709" [UniProtKB:Q8N972] xref: EMBL:BAC04584.1 xref: UniProtKB:Q8N972 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020912 ! ZNF709_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057534 name: ZN557_HUMAN def: "Zinc finger protein 557" [UniProtKB:Q8N988] xref: EMBL:AAH03020.1 xref: EMBL:AAH58040.1 xref: EMBL:BAC04567.1 xref: UniProtKB:Q6PEJ3 xref: UniProtKB:Q8N988 xref: UniProtKB:Q9BTZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020816 ! ZNF557_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057535 name: RGF1A_HUMAN def: "Ras-GEF domain-containing family member 1A" [UniProtKB:Q8N9B8] xref: EMBL:AAH22548.2 xref: EMBL:BAC04491.1 xref: UniProtKB:Q8N9B8 xref: UniProtKB:Q8TBF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019691 ! RASGEF1A_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057536 name: ZN454_HUMAN def: "Zinc finger protein 454" [UniProtKB:Q8N9F8] xref: EMBL:AAI05062.1 xref: EMBL:BAC04418.1 xref: UniProtKB:Q2M323 xref: UniProtKB:Q8N9F8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020758 ! ZNF454_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057537 name: DTX3_HUMAN def: "Protein deltex-3" [UniProtKB:Q8N9I9] synonym: "Deltex3" EXACT [UniProtKB:Q8N9I9] synonym: "RING finger protein 154" EXACT [UniProtKB:Q8N9I9] xref: EMBL:BAC03801.1 xref: EMBL:BAC04344.1 xref: EMBL:CAD38593.2 xref: UniProtKB:Q8N9I9 xref: UniProtKB:Q8NAU6 xref: UniProtKB:Q8NDS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017627 ! DTX3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0057538 name: ZN565_HUMAN def: "Zinc finger protein 565" [UniProtKB:Q8N9K5] xref: EMBL:AAH68453.1 xref: EMBL:BAC04328.1 xref: UniProtKB:Q6NUS2 xref: UniProtKB:Q8N9K5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020824 ! ZNF565_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057539 name: Q8N9M3_HUMAN def: "cDNA FLJ36883 fis, clone BLADE2000389, highly similar to ZINC FINGER PROTEIN 135" [UniProtKB:Q8N9M3] synonym: "Zinc finger protein 135 (Clone pHZ-17), isoform CRA_a" EXACT [UniProtKB:Q8N9M3] xref: EMBL:BAC04309.1 xref: EMBL:EAW72552.1 xref: UniProtKB:Q8N9M3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020624 ! ZNF135_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057540 name: ASCC1_HUMAN def: "Activating signal cointegrator 1 complex subunit 1" [UniProtKB:Q8N9N2] synonym: "ASC-1 complex subunit p50" EXACT [UniProtKB:Q8N9N2] synonym: "Trip4 complex subunit p50" EXACT [UniProtKB:Q8N9N2] xref: EMBL:AAD27727.1 xref: EMBL:AAG45476.1 xref: EMBL:AAH12291.1 xref: EMBL:BAC04299.1 xref: EMBL:BAG51193.1 xref: EMBL:CAI15907.1 xref: EMBL:CAI15908.1 xref: EMBL:EAW54444.1 xref: UniProtKB:Q5SW06 xref: UniProtKB:Q5SW07 xref: UniProtKB:Q8N9N2 xref: UniProtKB:Q96EI8 xref: UniProtKB:Q9Y307 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017074 ! ASCC1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057541 name: ZN610_HUMAN def: "Zinc finger protein 610" [UniProtKB:Q8N9Z0] xref: EMBL:AAH39903.1 xref: EMBL:AAI05968.1 xref: EMBL:BAC04144.1 xref: EMBL:CAD38559.1 xref: UniProtKB:Q86YH8 xref: UniProtKB:Q8N9Z0 xref: UniProtKB:Q8NDS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020852 ! ZNF610_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057542 name: LMBL4_HUMAN def: "Lethal(3)malignant brain tumor-like 4 protein" [UniProtKB:Q8NA19] synonym: "H-l(3)mbt-like protein" EXACT [UniProtKB:Q8NA19] synonym: "L(3)mbt-like 4 protein" EXACT [UniProtKB:Q8NA19] xref: EMBL:AAH39316.1 xref: EMBL:BAC04111.1 xref: EMBL:EAX01639.1 xref: UniProtKB:Q8IXS3 xref: UniProtKB:Q8NA19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018507 ! L3MBTL4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057543 name: CCD79_HUMAN def: "Coiled-coil domain-containing protein 79" [UniProtKB:Q8NA31] xref: EMBL:AAI26110.1 xref: EMBL:BAC04098.1 xref: UniProtKB:A0AUW1 xref: UniProtKB:Q8NA31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017257 ! CCDC79_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057544 name: ZN383_HUMAN def: "Zinc finger protein 383" [UniProtKB:Q8NA42] xref: EMBL:AAP20067.1 xref: EMBL:AAR14184.1 xref: EMBL:BAC04086.1 xref: UniProtKB:Q6X2C7 xref: UniProtKB:Q8NA42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020724 ! ZNF383_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057545 name: Q8NAE1_HUMAN def: "cDNA FLJ35492 fis, clone SMINT2008672, moderately similar to ZINC FINGER PROTEIN 191" [UniProtKB:Q8NAE1] synonym: "Zinc finger protein 483" EXACT [UniProtKB:Q8NAE1] xref: EMBL:BAC03981.1 xref: EMBL:CAH73466.1 xref: EMBL:CAI12406.1 xref: UniProtKB:Q8NAE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020769 ! ZNF483_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057546 name: ZN579_HUMAN def: "Zinc finger protein 579" [UniProtKB:Q8NAF0] xref: EMBL:BAC03972.1 xref: UniProtKB:Q8NAF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020836 ! ZNF579_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072161 ! ZN579_HUMAN-Phosphoserine483 [Term] id: CCO:B0057547 name: Q8NAM2_HUMAN def: "cDNA FLJ35118 fis, clone PLACE6007436, highly similar to Homo sapiens hairy and enhancer of split related-1 (HESR-1) mRNA" [UniProtKB:Q8NAM2] xref: EMBL:BAC03890.1 xref: UniProtKB:Q8NAM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057548 name: ZSCA4_HUMAN def: "Zinc finger and SCAN domain-containing protein 4" [UniProtKB:Q8NAM6] synonym: "Zinc finger protein 494" EXACT [UniProtKB:Q8NAM6] xref: EMBL:AAI01739.1 xref: EMBL:AAI01741.1 xref: EMBL:BAC03886.1 xref: UniProtKB:Q3MIQ2 xref: UniProtKB:Q8NAM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021009 ! ZSCAN4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057549 name: ZBT38_HUMAN def: "Zinc finger and BTB domain-containing protein 38" [UniProtKB:Q8NAP3] xref: EMBL:BAC03868.1 xref: UniProtKB:Q8NAP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020555 ! ZBTB38_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0071966 ! ZBT38_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0071967 ! ZBT38_HUMAN-Phosphoserine309 [Term] id: CCO:B0057550 name: ZBTB8_HUMAN def: "Zinc finger and BTB domain-containing protein 8" [UniProtKB:Q8NAP8] xref: EMBL:BAC03863.1 xref: UniProtKB:Q5VXR5 xref: UniProtKB:Q8NAP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020571 ! ZBTB8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057551 name: Q8NB10_HUMAN def: "cDNA FLJ34415 fis, clone HEART2004764, highly similar to CALCIUM/CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1C (EC 3.1.4.17)" [UniProtKB:Q8NB10] xref: EMBL:BAC03734.1 xref: UniProtKB:Q8NB10 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057552 name: SMYD1_HUMAN def: "SET and MYND domain-containing protein 1" [UniProtKB:Q8NB12] xref: EMBL:AAI26192.1 xref: EMBL:BAC03732.1 xref: EMBL:CAI46139.1 xref: UniProtKB:A0AV30 xref: UniProtKB:A6NE13 xref: UniProtKB:Q8NB12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019958 ! SMYD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0057553 name: ZN511_HUMAN def: "Zinc finger protein 511" [UniProtKB:Q8NB15] xref: EMBL:AAH15139.1 xref: EMBL:AAH19897.1 xref: EMBL:BAC03729.1 xref: EMBL:CAH70277.1 xref: EMBL:CAH70278.1 xref: UniProtKB:Q8NB15 xref: UniProtKB:Q8WUP1 xref: UniProtKB:Q96BV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020789 ! ZNF511_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057554 name: Q8NB18_HUMAN xref: UniProtKB:Q8NB18 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057555 name: ZN527_HUMAN def: "Zinc finger protein 527" [UniProtKB:Q8NB42] xref: EMBL:BAC03701.1 xref: UniProtKB:Q8NB42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020798 ! ZNF527_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057556 name: UN13C_HUMAN def: "Protein unc-13 homolog C" [UniProtKB:Q8NB66] synonym: "Munc13-3" EXACT [UniProtKB:Q8NB66] xref: EMBL:AAH40740.1 xref: EMBL:BAB70836.1 xref: EMBL:BAC03675.1 xref: EMBL:CAD39069.2 xref: UniProtKB:Q0P613 xref: UniProtKB:Q8NB66 xref: UniProtKB:Q8ND48 xref: UniProtKB:Q96NP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020409 ! UNC13C_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057557 name: ZSCA1_HUMAN def: "Zinc finger and SCAN domain-containing protein 1" [UniProtKB:Q8NBB4] xref: EMBL:AAH48099.1 xref: EMBL:AAQ16582.1 xref: EMBL:BAC03582.1 xref: UniProtKB:Q6WLH8 xref: UniProtKB:Q86WS8 xref: UniProtKB:Q8NBB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021007 ! ZSCAN1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057558 name: PCSK9_HUMAN def: "Proprotein convertase subtilisin/kexin type 9 precursor" [UniProtKB:Q8NBP7] synonym: "EC 3.4.21.-" EXACT [UniProtKB:Q8NBP7] synonym: "NARC-1" EXACT [UniProtKB:Q8NBP7] synonym: "Neural apoptosis-regulated convertase 1" EXACT [UniProtKB:Q8NBP7] synonym: "Proprotein convertase PC9" EXACT [UniProtKB:Q8NBP7] synonym: "Subtilisin/kexin-like protease PC9" EXACT [UniProtKB:Q8NBP7] xref: EMBL:AAV67948.1 xref: EMBL:ABV59216.1 xref: EMBL:BAC11572.1 xref: EMBL:BAC85910.1 xref: EMBL:CAC38896.1 xref: EMBL:CAI17845.1 xref: EMBL:EAX06660.1 xref: UniProtKB:A8T640 xref: UniProtKB:Q5PSM5 xref: UniProtKB:Q5SZQ2 xref: UniProtKB:Q8NBP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019325 ! PCSK9_human relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000715 ! subtilase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003378 ! proprotein convertase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000372 ! rough endoplasmic reticulum relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002234 ! positive regulation of neuron apoptosis relationship: transforms_into CCO:B0069155 ! PCSK9_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0069156 ! PCSK9_HUMAN-Phosphoserine688 [Term] id: CCO:B0057559 name: TXND5_HUMAN def: "Thioredoxin domain-containing protein 5 precursor" [UniProtKB:Q8NBS9] synonym: "Endoplasmic reticulum protein ERp46" EXACT [UniProtKB:Q8NBS9] synonym: "Thioredoxin-like protein p46" EXACT [UniProtKB:Q8NBS9] xref: EMBL:AAH01199.1 xref: EMBL:AAQ89009.1 xref: EMBL:BAC11526.1 xref: EMBL:CAD29430.1 xref: EMBL:CAD39084.1 xref: EMBL:CAI19473.1 xref: UniProtKB:Q5TCQ0 xref: UniProtKB:Q8NBS9 xref: UniProtKB:Q8ND33 xref: UniProtKB:Q8TCT2 xref: UniProtKB:Q9BVH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020392 ! TXNDC5_human relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0057560 name: CLC1A_HUMAN def: "C-type lectin domain family 1 member A" [UniProtKB:Q8NC01] synonym: "C-type lectin-like receptor 1" EXACT [UniProtKB:Q8NC01] synonym: "CLEC-1" EXACT [UniProtKB:Q8NC01] xref: EMBL:AAF36830.1 xref: EMBL:AAH39072.1 xref: EMBL:AAH67746.1 xref: EMBL:AAQ88950.1 xref: EMBL:BAC11410.1 xref: UniProtKB:Q8IUW7 xref: UniProtKB:Q8NC01 xref: UniProtKB:Q9NZH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017375 ! CLEC1A_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0057561 name: ZN114_HUMAN def: "Zinc finger protein 114" [UniProtKB:Q8NC26] xref: EMBL:AAI25069.1 xref: EMBL:AAI25070.1 xref: EMBL:BAC11378.1 xref: UniProtKB:Q08AQ6 xref: UniProtKB:Q8NC26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020617 ! ZNF114_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057562 name: Q8NC36_HUMAN xref: UniProtKB:Q8NC36 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057563 name: Q8NC81_HUMAN def: "cDNA FLJ90425 fis, clone NT2RP3000444 (Caspase recruitment domain family, member 10)" [UniProtKB:Q8NC81] xref: EMBL:BAC11282.1 xref: EMBL:CAQ08761.1 xref: EMBL:CAQ10191.1 xref: UniProtKB:Q8NC81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017227 ! CARD10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity [Term] id: CCO:B0057564 name: ZN784_HUMAN def: "Zinc finger protein 784" [UniProtKB:Q8NCA9] xref: EMBL:AAH65822.1 xref: EMBL:BAC11251.1 xref: UniProtKB:Q8NCA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020938 ! ZNF784_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057565 name: NF2IP_HUMAN def: "NFATC2-interacting protein" [UniProtKB:Q8NCF5] synonym: "45 kDa NF-AT-interacting protein" EXACT [UniProtKB:Q8NCF5] synonym: "45 kDa NFAT-interacting protein" EXACT [UniProtKB:Q8NCF5] synonym: "Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein" EXACT [UniProtKB:Q8NCF5] xref: EMBL:AAH18311.1 xref: EMBL:AAH21551.1 xref: EMBL:AAH68007.1 xref: EMBL:AAH80628.1 xref: EMBL:AAI01742.1 xref: EMBL:AAI12183.1 xref: EMBL:AAM49721.1 xref: EMBL:BAB55189.1 xref: EMBL:BAC11189.1 xref: UniProtKB:Q66K34 xref: UniProtKB:Q6NVK1 xref: UniProtKB:Q8NCF5 xref: UniProtKB:Q8NFR2 xref: UniProtKB:Q96ST9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018762 ! NFATC2IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068591 ! NF2IP_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0068592 ! NF2IP_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0068593 ! NF2IP_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0068594 ! NF2IP_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0068595 ! NF2IP_HUMAN-Phosphoserine198 relationship: transforms_into CCO:B0068596 ! NF2IP_HUMAN-Phosphoserine201 relationship: transforms_into CCO:B0068597 ! NF2IP_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0068598 ! NF2IP_HUMAN-Phosphothreonine316 relationship: transforms_into CCO:B0068599 ! NF2IP_HUMAN-Phosphoserine369 relationship: transforms_into CCO:B0068600 ! NF2IP_HUMAN-Phosphoserine390 [Term] id: CCO:B0057566 name: Q8NCF9_HUMAN def: "cDNA FLJ90276 fis, clone NT2RP1000271, moderately similar to ZINC FINGER PROTEIN 85" [UniProtKB:Q8NCF9] xref: EMBL:BAC11185.1 xref: UniProtKB:Q8NCF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057567 name: Q8NCH7_HUMAN def: "cDNA FLJ90245 fis, clone NT2RM2001792, highly similar to Homo sapiens angiopoietin-related protein-2 mRNA" [UniProtKB:Q8NCH7] synonym: "Angiopoietin-like 2" EXACT [UniProtKB:Q8NCH7] synonym: "Angiopoietin-like 2, isoform CRA_c" EXACT [UniProtKB:Q8NCH7] xref: EMBL:BAC11164.1 xref: EMBL:CAI39724.1 xref: EMBL:EAW87651.1 xref: UniProtKB:Q8NCH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016966 ! ANGPTL2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057568 name: ZN485_HUMAN def: "Zinc finger protein 485" [UniProtKB:Q8NCK3] xref: EMBL:AAH14161.1 xref: EMBL:BAC11133.1 xref: EMBL:CAH73487.1 xref: UniProtKB:Q8NCK3 xref: UniProtKB:Q96CL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020771 ! ZNF485_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057569 name: Q8NCK8_HUMAN def: "cDNA FLJ38565 fis, clone HCHON2005048, highly similar to Serine/threonine-protein kinase D2 (EC 2.7.11.13)" [UniProtKB:Q8NCK8] synonym: "cDNA FLJ90192 fis, clone MAMMA1001150, moderately similar to PROTEIN KINASE C, MU TYPE (EC 2.7.1.-)" EXACT [UniProtKB:Q8NCK8] xref: EMBL:BAC11127.1 xref: EMBL:BAG53158.1 xref: UniProtKB:Q8NCK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057570 name: KCNH5_HUMAN def: "Potassium voltage-gated channel subfamily H member 5" [UniProtKB:Q8NCM2] synonym: "Ether-a-go-go potassium channel 2" EXACT [UniProtKB:Q8NCM2] synonym: "hEAG2" EXACT [UniProtKB:Q8NCM2] synonym: "Voltage-gated potassium channel subunit Kv10.2" EXACT [UniProtKB:Q8NCM2] xref: EMBL:AAH73979.1 xref: EMBL:AAM28435.1 xref: EMBL:AAM49565.1 xref: EMBL:AAM49574.1 xref: EMBL:BAC11016.1 xref: UniProtKB:Q8NCM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018394 ! KCNH5_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057571 name: ZBT34_HUMAN def: "Zinc finger and BTB domain-containing protein 34" [UniProtKB:Q8NCN2] xref: EMBL:ABA86591.1 xref: EMBL:BAC02702.1 xref: EMBL:CAH69994.1 xref: UniProtKB:Q38IA7 xref: UniProtKB:Q5VYE9 xref: UniProtKB:Q8NCN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020553 ! ZBTB34_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057572 name: ZBT44_HUMAN def: "Zinc finger and BTB domain-containing protein 44" [UniProtKB:Q8NCP5] synonym: "BTB/POZ domain-containing protein 15" EXACT [UniProtKB:Q8NCP5] xref: EMBL:AAH30580.1 xref: EMBL:AAH49375.1 xref: EMBL:AAH50723.1 xref: EMBL:AAH71729.1 xref: UniProtKB:Q6IPT8 xref: UniProtKB:Q86VJ7 xref: UniProtKB:Q86XX5 xref: UniProtKB:Q8NCP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020559 ! ZBTB44_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071972 ! ZBT44_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0071973 ! ZBT44_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0071974 ! ZBT44_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0071975 ! ZBT44_HUMAN-Phosphoserine194 [Term] id: CCO:B0057573 name: Q8NCR5_HUMAN def: "USP6 protein" [UniProtKB:Q8NCR5] xref: EMBL:AAH29495.2 xref: UniProtKB:Q8NCR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020401 ! USP6_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057574 name: KREM2_HUMAN def: "Kremen protein 2 precursor" [UniProtKB:Q8NCW0] synonym: "Dickkopf receptor 2" EXACT [UniProtKB:Q8NCW0] synonym: "Kringle domain-containing transmembrane protein 2" EXACT [UniProtKB:Q8NCW0] synonym: "Kringle-containing protein marking the eye and the nose" EXACT [UniProtKB:Q8NCW0] xref: EMBL:AAH03533.1 xref: EMBL:AAH09383.1 xref: EMBL:BAB55281.1 xref: EMBL:BAC00823.1 xref: EMBL:BAC00824.1 xref: EMBL:BAC00825.1 xref: EMBL:BAC00872.1 xref: EMBL:BAC11365.1 xref: UniProtKB:Q8N2J4 xref: UniProtKB:Q8NCW0 xref: UniProtKB:Q8NCW1 xref: UniProtKB:Q96GL8 xref: UniProtKB:Q9BTP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018438 ! KREMEN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0057575 name: Z280C_HUMAN def: "Zinc finger protein 280C" [UniProtKB:Q8ND82] synonym: "Suppressor of hairy wing homolog 3" EXACT [UniProtKB:Q8ND82] xref: EMBL:AAH51728.1 xref: EMBL:BAA90947.1 xref: EMBL:CAD39001.1 xref: EMBL:CAI42593.1 xref: EMBL:CAI42782.1 xref: UniProtKB:Q8ND82 xref: UniProtKB:Q9NXR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020516 ! ZNF280C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071932 ! Z280C_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0071933 ! Z280C_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0071934 ! Z280C_HUMAN-Phosphoserine115 relationship: transforms_into CCO:B0071935 ! Z280C_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0071936 ! Z280C_HUMAN-Phosphothreonine540 [Term] id: CCO:B0057576 name: Q8NDC7_HUMAN def: "Putative uncharacterized protein DKFZp547B0614" [UniProtKB:Q8NDC7] xref: EMBL:CAD38953.1 xref: UniProtKB:Q8NDC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021231 ! DKFZp547B0614_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057577 name: ZN439_HUMAN def: "Zinc finger protein 439" [UniProtKB:Q8NDP4] xref: EMBL:AAH32857.1 xref: EMBL:BAB55187.1 xref: EMBL:CAD38790.1 xref: UniProtKB:Q8IYZ7 xref: UniProtKB:Q8NDP4 xref: UniProtKB:Q96SU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020751 ! ZNF439_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015352 ! krtap4_12-znf439 physical interaction relationship: participates_in CCO:I0015398 ! mdfi-znf439 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057578 name: ZN540_HUMAN def: "Zinc finger protein 540" [UniProtKB:Q8NDQ6] xref: EMBL:AAI26479.1 xref: EMBL:AAI26481.1 xref: EMBL:BAD18539.1 xref: EMBL:CAD38611.1 xref: EMBL:CAD91161.1 xref: EMBL:CAD97942.1 xref: UniProtKB:A0AVS5 xref: UniProtKB:Q6ZN36 xref: UniProtKB:Q7Z3C8 xref: UniProtKB:Q86T31 xref: UniProtKB:Q8NDQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020804 ! ZNF540_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057579 name: Q8NDS5_HUMAN def: "Microtubule-associated protein" [UniProtKB:Q8NDS5] xref: EMBL:CAD38562.1 xref: UniProtKB:Q8NDS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021232 ! DKFZp547H1810_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization [Term] id: CCO:B0057580 name: ZN663_HUMAN def: "Zinc finger protein 663" [UniProtKB:Q8NDT4] xref: EMBL:CAD38590.1 xref: UniProtKB:Q8NDT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020881 ! ZNF663_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057581 name: GPR26_HUMAN def: "Probable G-protein coupled receptor 26" [UniProtKB:Q8NDV2] xref: EMBL:AAI12012.1 xref: EMBL:AAI13463.1 xref: EMBL:CAD44281.1 xref: UniProtKB:Q2M2E2 xref: UniProtKB:Q8NDV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018012 ! GPR26_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057582 name: Q8NDV8_HUMAN def: "ZNF248 protein" [UniProtKB:Q8NDV8] synonym: "Zinc finger protein 248" EXACT [UniProtKB:Q8NDV8] synonym: "Zinc finger protein 248, isoform CRA_b" EXACT [UniProtKB:Q8NDV8] xref: EMBL:AAI10870.1 xref: EMBL:AAI46821.1 xref: EMBL:CAD37332.1 xref: EMBL:CAI12320.1 xref: EMBL:EAW85897.1 xref: UniProtKB:Q8NDV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020677 ! ZNF248_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057583 name: ZN248_HUMAN def: "Zinc finger protein 248" [UniProtKB:Q8NDW4] xref: EMBL:CAB52547.1 xref: EMBL:CAD36954.1 xref: UniProtKB:Q8NDW4 xref: UniProtKB:Q9UMP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020677 ! ZNF248_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072074 ! ZN248_HUMAN-Phosphoserine142 [Term] id: CCO:B0057584 name: PSD4_HUMAN def: "PH and SEC7 domain-containing protein 4" [UniProtKB:Q8NDX1] synonym: "Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B" EXACT [UniProtKB:Q8NDX1] synonym: "Pleckstrin homology and SEC7 domain-containing protein 4" EXACT [UniProtKB:Q8NDX1] synonym: "Telomeric of interleukin-1 cluster protein" EXACT [UniProtKB:Q8NDX1] xref: EMBL:AAD00107.1 xref: EMBL:AAH35307.1 xref: EMBL:AAH73151.1 xref: EMBL:AAX88879.1 xref: EMBL:ABD96831.1 xref: EMBL:CAD30842.1 xref: UniProtKB:A6NEG7 xref: UniProtKB:O95621 xref: UniProtKB:Q4ZG34 xref: UniProtKB:Q6GPH8 xref: UniProtKB:Q8IYP4 xref: UniProtKB:Q8NDX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019527 ! PSD4_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0057585 name: ZN740_HUMAN def: "Zinc finger protein 740" [UniProtKB:Q8NDX6] synonym: "OriLyt TD-element-binding protein 7" EXACT [UniProtKB:Q8NDX6] xref: EMBL:AAH53557.1 xref: EMBL:CAC86954.1 xref: UniProtKB:Q8NDX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020922 ! ZNF740_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072231 ! ZN740_HUMAN-Phosphoserine44 [Term] id: CCO:B0057586 name: BHLH4_HUMAN def: "Class B basic helix-loop-helix protein 4" [UniProtKB:Q8NDY6] synonym: "bHLHB4" EXACT [UniProtKB:Q8NDY6] xref: EMBL:CAD37449.1 xref: EMBL:DAA01054.1 xref: UniProtKB:Q8NDY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017147 ! BHLHB4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002728 ! negative regulation of retinal cell programmed cell death [Term] id: CCO:B0057587 name: RGS22_HUMAN def: "Regulator of G-protein signaling 22" [UniProtKB:Q8NE09] synonym: "RGS22" EXACT [UniProtKB:Q8NE09] xref: EMBL:AAH36665.2 xref: EMBL:AAH47060.1 xref: EMBL:AAH92411.1 xref: EMBL:CAB55986.2 xref: UniProtKB:Q569L2 xref: UniProtKB:Q86Y71 xref: UniProtKB:Q8NE09 xref: UniProtKB:Q9UFN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019703 ! RGS22_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0057588 name: GMCLL_HUMAN def: "Germ cell-less protein-like 1-like" [UniProtKB:Q8NEA9] xref: EMBL:AAH24184.1 xref: EMBL:AAH24185.1 xref: EMBL:AAH33886.1 xref: UniProtKB:Q8NEA9 xref: UniProtKB:Q8TC88 xref: UniProtKB:Q8TC89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017937 ! GMCL1L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:I0015200 ! gage5-gmcl1l physical interaction relationship: participates_in CCO:I0015757 ! gage8-gmcl1l physical interaction relationship: participates_in CCO:I0019411 ! gage8-gmcl1l-1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066472 ! GMCLL_HUMAN-Phosphotyrosine424 [Term] id: CCO:B0057589 name: PK3C3_HUMAN def: "Phosphatidylinositol 3-kinase catalytic subunit type 3" [UniProtKB:Q8NEB9] synonym: "EC 2.7.1.137" EXACT [UniProtKB:Q8NEB9] synonym: "Phosphatidylinositol 3-kinase p100 subunit" EXACT [UniProtKB:Q8NEB9] synonym: "Phosphoinositide-3-kinase class 3" EXACT [UniProtKB:Q8NEB9] synonym: "PI3-kinase type 3" EXACT [UniProtKB:Q8NEB9] synonym: "PI3K type 3" EXACT [UniProtKB:Q8NEB9] synonym: "PtdIns-3-kinase type 3" EXACT [UniProtKB:Q8NEB9] xref: EMBL:AAH33004.1 xref: EMBL:AAH53651.1 xref: EMBL:CAA87094.1 xref: UniProtKB:Q15134 xref: UniProtKB:Q8NEB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019408 ! PIK3C3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0069319 ! PK3C3_HUMAN-Phosphoserine525 [Term] id: CCO:B0057590 name: SRFB1_HUMAN def: "Serum response factor-binding protein 1" [UniProtKB:Q8NEF9] synonym: "p49/STRAP" EXACT [UniProtKB:Q8NEF9] synonym: "SRF-dependent transcription regulation-associated protein" EXACT [UniProtKB:Q8NEF9] xref: EMBL:AAH17102.1 xref: EMBL:AAH31222.1 xref: EMBL:AAU25829.2 xref: EMBL:BAB71631.1 xref: EMBL:EAW48900.1 xref: UniProtKB:Q5QFI2 xref: UniProtKB:Q8NEF9 xref: UniProtKB:Q96AH4 xref: UniProtKB:Q96DK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020035 ! SRFBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070905 ! SRFB1_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0070906 ! SRFB1_HUMAN-Phosphotyrosine270 relationship: transforms_into CCO:B0070907 ! SRFB1_HUMAN-Phosphoserine273 relationship: transforms_into CCO:B0070908 ! SRFB1_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0070909 ! SRFB1_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0070910 ! SRFB1_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0070911 ! SRFB1_HUMAN-Phosphoserine281 [Term] id: CCO:B0057591 name: NGDN_HUMAN def: "Neuroguidin" [UniProtKB:Q8NEJ9] synonym: "EIF4E-binding protein" EXACT [UniProtKB:Q8NEJ9] xref: EMBL:AAH30817.1 xref: EMBL:CAB43232.2 xref: UniProtKB:Q8NEJ9 xref: UniProtKB:Q9Y400 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018783 ! NGDN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0002175 ! small-subunit processome relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0068702 ! NGDN_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0068703 ! NGDN_HUMAN-Phosphoserine143 [Term] id: CCO:B0057592 name: PDZD8_HUMAN def: "PDZ domain-containing protein 8" [UniProtKB:Q8NEN9] synonym: "Sarcoma antigen NY-SAR-84/NY-SAR-104" EXACT [UniProtKB:Q8NEN9] xref: EMBL:AAH28375.1 xref: EMBL:AAO65177.1 xref: EMBL:AAO65182.1 xref: EMBL:CAB59184.1 xref: EMBL:CAH70347.1 xref: EMBL:CAH73253.1 xref: UniProtKB:Q86WE0 xref: UniProtKB:Q86WE5 xref: UniProtKB:Q8NEN9 xref: UniProtKB:Q9UFF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019354 ! PDZD8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069195 ! PDZD8_HUMAN-Phosphoserine496 relationship: transforms_into CCO:B0069196 ! PDZD8_HUMAN-Phosphoserine538 [Term] id: CCO:B0057593 name: ZN555_HUMAN def: "Zinc finger protein 555" [UniProtKB:Q8NEP9] xref: EMBL:AAH22022.2 xref: EMBL:BAB71244.1 xref: EMBL:BAC04082.1 xref: UniProtKB:Q8NA46 xref: UniProtKB:Q8NEP9 xref: UniProtKB:Q96MP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020814 ! ZNF555_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057594 name: Q8NER4_HUMAN def: "PMEPA1 variant A protein" [UniProtKB:Q8NER4] synonym: "Transmembrane, prostate androgen induced RNA" EXACT [UniProtKB:Q8NER4] synonym: "Transmembrane, prostate androgen induced RNA, isoform CRA_b" EXACT [UniProtKB:Q8NER4] xref: EMBL:AAM89277.1 xref: EMBL:CAM27272.1 xref: EMBL:CAM28295.1 xref: EMBL:EAW75505.1 xref: UniProtKB:Q8NER4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021233 ! TMEPAI_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway [Term] id: CCO:B0057595 name: NFAM1_HUMAN def: "NFAT activation molecule 1 precursor" [UniProtKB:Q8NET5] synonym: "Calcineurin/NFAT-activating ITAM-containing protein" EXACT [UniProtKB:Q8NET5] synonym: "NFAT-activating protein with ITAM motif 1" EXACT [UniProtKB:Q8NET5] xref: EMBL:AAH38241.2 xref: EMBL:AAM83133.1 xref: EMBL:AAO91847.1 xref: EMBL:BAB84920.1 xref: EMBL:CAJ86439.1 xref: EMBL:CAQ10428.1 xref: EMBL:EAW60505.1 xref: UniProtKB:B0QYD0 xref: UniProtKB:Q20WL2 xref: UniProtKB:Q5JZ96 xref: UniProtKB:Q8IUY8 xref: UniProtKB:Q8NET5 xref: UniProtKB:Q8TEM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018769 ! NFAM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002979 ! positive regulation of B cell receptor signaling pathway relationship: participates_in CCO:P0003022 ! positive regulation of transcription factor activity relationship: transforms_into CCO:B0068633 ! NFAM1_HUMAN-Phosphotyrosine220 relationship: transforms_into CCO:B0068634 ! NFAM1_HUMAN-Phosphotyrosine231 [Term] id: CCO:B0057596 name: IL27A_HUMAN def: "Interleukin-27 subunit alpha precursor" [UniProtKB:Q8NEV9] synonym: "IL-27 subunit alpha" EXACT [UniProtKB:Q8NEV9] synonym: "IL27-A" EXACT [UniProtKB:Q8NEV9] synonym: "p28" EXACT [UniProtKB:Q8NEV9] xref: EMBL:AAH62422.1 xref: EMBL:AAM34498.1 xref: EMBL:ABK41903.1 xref: EMBL:EAW52277.1 xref: UniProtKB:A0N0L2 xref: UniProtKB:Q6P676 xref: UniProtKB:Q8NEV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018259 ! IL27_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006154 ! interleukin-27 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0002046 ! regulation of T cell proliferation relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002439 ! regulation of T-helper 1 cell differentiation [Term] id: CCO:B0057597 name: ZN397_HUMAN def: "Zinc finger protein 397" [UniProtKB:Q8NF99] synonym: "Zinc finger and SCAN domain-containing protein 15" EXACT [UniProtKB:Q8NF99] synonym: "Zinc finger protein 47" EXACT [UniProtKB:Q8NF99] xref: EMBL:AAH06172.1 xref: EMBL:AAM95991.2 xref: EMBL:AAN65175.1 xref: UniProtKB:Q8NF99 xref: UniProtKB:Q9BRM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020730 ! ZNF397_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072120 ! ZN397_HUMAN-Phosphoserine159 [Term] id: CCO:B0057598 name: NOXO1_HUMAN def: "NADPH oxidase organizer 1" [UniProtKB:Q8NFA2] synonym: "NADPH oxidase regulatory protein" EXACT [UniProtKB:Q8NFA2] synonym: "Nox organizer 1" EXACT [UniProtKB:Q8NFA2] synonym: "Nox-organizing protein 1" EXACT [UniProtKB:Q8NFA2] synonym: "SH3 and PX domain-containing protein 5" EXACT [UniProtKB:Q8NFA2] xref: EMBL:AAH15917.1 xref: EMBL:AAM97925.1 xref: EMBL:AAM97926.1 xref: EMBL:AAM97927.1 xref: EMBL:AAN75141.1 xref: EMBL:AAO38665.1 xref: EMBL:AAP13479.1 xref: EMBL:BAC76711.1 xref: UniProtKB:Q86YM1 xref: UniProtKB:Q8NFA2 xref: UniProtKB:Q8NFA3 xref: UniProtKB:Q96B73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018825 ! NOXO1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003064 ! superoxide-generating NADPH oxidase activator activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001708 ! NADPH oxidase complex relationship: participates_in CCO:P0000922 ! regulation of hydrogen peroxide metabolic process [Term] id: CCO:B0057599 name: ARI1B_HUMAN def: "AT-rich interactive domain-containing protein 1B" [UniProtKB:Q8NFD5] synonym: "ARID domain-containing protein 1B" EXACT [UniProtKB:Q8NFD5] synonym: "BAF250B" EXACT [UniProtKB:Q8NFD5] synonym: "BRG1-associated factor 250b" EXACT [UniProtKB:Q8NFD5] synonym: "BRG1-binding protein hELD/OSA1" EXACT [UniProtKB:Q8NFD5] synonym: "hOsa2" EXACT [UniProtKB:Q8NFD5] synonym: "Osa homolog 2" EXACT [UniProtKB:Q8NFD5] synonym: "p250R" EXACT [UniProtKB:Q8NFD5] xref: EMBL:AAG36928.1 xref: EMBL:AAL76077.1 xref: EMBL:AAN03447.1 xref: EMBL:AAN70985.1 xref: EMBL:BAA86549.1 xref: EMBL:CAA69592.1 xref: EMBL:CAH71534.1 xref: EMBL:CAI40014.1 xref: EMBL:CAI40664.1 xref: EMBL:CAI40666.1 xref: EMBL:CAI42305.1 xref: EMBL:CAI42308.1 xref: UniProtKB:Q5JRD1 xref: UniProtKB:Q5VYC4 xref: UniProtKB:Q8IZY8 xref: UniProtKB:Q8NFD5 xref: UniProtKB:Q8TEV0 xref: UniProtKB:Q8TF02 xref: UniProtKB:Q99491 xref: UniProtKB:Q9ULI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017027 ! ARID1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017884 ! smarca4-arid1b-1 physical interaction relationship: participates_in CCO:I0017885 ! arid1b-smarca4-1 physical interaction relationship: participates_in CCO:I0017886 ! arid1b-smarca2-2 physical interaction relationship: participates_in CCO:I0018069 ! smarca2-arid1b-1 physical interaction relationship: participates_in CCO:I0018326 ! arid1b-smarca2-3 physical interaction relationship: participates_in CCO:I0018329 ! arid1b-smarca4-5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002770 ! chromatin-mediated maintenance of transcription relationship: transforms_into CCO:B0063571 ! ARI1B_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0063572 ! ARI1B_HUMAN-Phosphoserine1555 relationship: transforms_into CCO:B0063573 ! ARI1B_HUMAN-Phosphoserine1559 [Term] id: CCO:B0057600 name: Q8NFD8_HUMAN def: "Platelet receptor for type III collagen" [UniProtKB:Q8NFD8] xref: EMBL:AAM80488.1 xref: UniProtKB:Q8NFD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001649 ! collagen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion [Term] id: CCO:B0057601 name: Q8NFF3_HUMAN def: "Pro-apoptotic protein BAKM variant" [UniProtKB:Q8NFF3] xref: EMBL:AAM74949.1 xref: UniProtKB:Q8NFF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021234 ! BAK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0057602 name: REPS2_HUMAN def: "RalBP1-associated Eps domain-containing protein 2" [UniProtKB:Q8NFH8] synonym: "Partner of RalBP1" EXACT [UniProtKB:Q8NFH8] synonym: "RalBP1-interacting protein 2" EXACT [UniProtKB:Q8NFH8] xref: EMBL:AAC02901.1 xref: EMBL:AAM43933.1 xref: EMBL:AAM43953.1 xref: UniProtKB:O43428 xref: UniProtKB:Q8NFH8 xref: UniProtKB:Q8NFI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019673 ! REPS2_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: transforms_into CCO:B0069873 ! REPS2_HUMAN-Phosphoserine260 [Term] id: CCO:B0057603 name: RAI3_HUMAN def: "Retinoic acid-induced protein 3" [UniProtKB:Q8NFJ5] synonym: "G-protein coupled receptor family C group 5 member A" EXACT [UniProtKB:Q8NFJ5] synonym: "Orphan G-protein-coupling receptor PEIG-1" EXACT [UniProtKB:Q8NFJ5] synonym: "RAIG-1" EXACT [UniProtKB:Q8NFJ5] synonym: "Retinoic acid-induced gene 1 protein" EXACT [UniProtKB:Q8NFJ5] xref: EMBL:AAC98506.1 xref: EMBL:AAH03665.1 xref: EMBL:AAM77594.1 xref: EMBL:BAA91890.1 xref: UniProtKB:O95357 xref: UniProtKB:Q8NFJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019616 ! GPRC5A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0069717 ! RAI3_HUMAN-Phosphotyrosine317 relationship: transforms_into CCO:B0069718 ! RAI3_HUMAN-Phosphotyrosine320 relationship: transforms_into CCO:B0069719 ! RAI3_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0069720 ! RAI3_HUMAN-Phosphotyrosine347 relationship: transforms_into CCO:B0069721 ! RAI3_HUMAN-Phosphotyrosine350 [Term] id: CCO:B0057604 name: PKR2_HUMAN def: "Prokineticin receptor 2" [UniProtKB:Q8NFJ6] synonym: "G-protein coupled receptor 73-like 1" EXACT [UniProtKB:Q8NFJ6] synonym: "GPR73b" EXACT [UniProtKB:Q8NFJ6] synonym: "GPRg2" EXACT [UniProtKB:Q8NFJ6] synonym: "PK-R2" EXACT [UniProtKB:Q8NFJ6] xref: EMBL:AAI04960.1 xref: EMBL:AAI04962.1 xref: EMBL:AAM48128.1 xref: EMBL:BAC24022.1 xref: EMBL:CAI22379.1 xref: UniProtKB:Q2M3C0 xref: UniProtKB:Q5TDY1 xref: UniProtKB:Q8NFJ6 xref: UniProtKB:Q9NTT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019426 ! PROKR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057605 name: BHLH5_HUMAN def: "Class B basic helix-loop-helix protein 5" [UniProtKB:Q8NFJ8] synonym: "bHLHB5" EXACT [UniProtKB:Q8NFJ8] synonym: "Trinucleotide repeat-containing gene 20 protein" EXACT [UniProtKB:Q8NFJ8] xref: EMBL:AAM28881.1 xref: EMBL:DAA01053.1 xref: UniProtKB:Q8NFJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017148 ! BHLHB5_human relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057606 name: GP156_HUMAN def: "Probable G-protein coupled receptor 156" [UniProtKB:Q8NFN8] synonym: "G-protein coupled receptor PGR28" EXACT [UniProtKB:Q8NFN8] synonym: "GABAB-related G-protein coupled receptor" EXACT [UniProtKB:Q8NFN8] xref: EMBL:AAI13702.1 xref: EMBL:AAN03795.1 xref: EMBL:AAO85077.1 xref: UniProtKB:Q14CM1 xref: UniProtKB:Q86SN6 xref: UniProtKB:Q8NFN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017979 ! GPR156_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001306 ! GABA-B receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057607 name: Q8NFP1_HUMAN def: "Pol protein" [UniProtKB:Q8NFP1] xref: EMBL:AAM81188.1 xref: UniProtKB:Q8NFP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0057608 name: DNER_HUMAN def: "Delta and Notch-like epidermal growth factor-related receptor precursor" [UniProtKB:Q8NFT8] xref: EMBL:AAF19247.2 xref: EMBL:AAH24766.2 xref: EMBL:AAH35009.1 xref: EMBL:AAM21557.1 xref: EMBL:AAQ89250.1 xref: EMBL:AAY14680.1 xref: EMBL:AAY14939.1 xref: EMBL:AAY24263.1 xref: EMBL:CAB70690.1 xref: EMBL:EAW70893.1 xref: UniProtKB:A6NP39 xref: UniProtKB:Q53R88 xref: UniProtKB:Q53TP7 xref: UniProtKB:Q53TQ5 xref: UniProtKB:Q8IYT0 xref: UniProtKB:Q8NFT8 xref: UniProtKB:Q8TB42 xref: UniProtKB:Q9NTF1 xref: UniProtKB:Q9UDM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017595 ! DNER_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000755 ! Notch receptor processing relationship: transforms_into CCO:B0064791 ! DNER_HUMAN-Phosphotyrosine711 relationship: transforms_into CCO:B0064792 ! DNER_HUMAN-Phosphotyrosine718 relationship: transforms_into CCO:B0064793 ! DNER_HUMAN-Phosphotyrosine721 [Term] id: CCO:B0057609 name: DMBX1_HUMAN def: "Diencephalon/mesencephalon homeobox protein 1" [UniProtKB:Q8NFW5] synonym: "Orthodenticle homolog 3" EXACT [UniProtKB:Q8NFW5] synonym: "Paired-like homeobox protein DMBX1" EXACT [UniProtKB:Q8NFW5] xref: EMBL:AAM90589.1 xref: EMBL:AAM90590.1 xref: EMBL:BAC00920.1 xref: EMBL:CAI19184.1 xref: EMBL:CAI19185.1 xref: EMBL:EAX06907.1 xref: UniProtKB:A6NNN2 xref: UniProtKB:Q8NFW5 xref: UniProtKB:Q8NFW6 xref: UniProtKB:Q8NHD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017585 ! DMBX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057610 name: VN1R2_HUMAN def: "Vomeronasal type-1 receptor 2" [UniProtKB:Q8NFZ6] synonym: "hGPCR25" EXACT [UniProtKB:Q8NFZ6] synonym: "V1r-like receptor 2" EXACT [UniProtKB:Q8NFZ6] xref: EMBL:AAM83034.1 xref: EMBL:AAP85615.1 xref: EMBL:AAP85616.1 xref: EMBL:AAP85617.1 xref: EMBL:BAB89320.1 xref: UniProtKB:Q8NFZ6 xref: UniProtKB:Q8TDU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020455 ! VN1R2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057611 name: HELB_HUMAN def: "DNA helicase B" [UniProtKB:Q8NG08] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q8NG08] synonym: "hDHB" EXACT [UniProtKB:Q8NG08] xref: EMBL:AAH37946.1 xref: EMBL:AAM73554.1 xref: EMBL:BAB15754.1 xref: EMBL:BAF83583.1 xref: UniProtKB:A8K4C9 xref: UniProtKB:Q4G0T2 xref: UniProtKB:Q8NG08 xref: UniProtKB:Q9H7L5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018113 ! HELB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000633 ! DNA replication, synthesis of RNA primer relationship: transforms_into CCO:B0066791 ! HELB_HUMAN-Phosphoserine708 relationship: transforms_into CCO:B0066792 ! HELB_HUMAN-Phosphoserine709 relationship: transforms_into CCO:B0066793 ! HELB_HUMAN-Phosphoserine967 relationship: transforms_into CCO:B0066794 ! HELB_HUMAN-Phosphoserine971 relationship: transforms_into CCO:B0066795 ! HELB_HUMAN-Phosphoserine1021 relationship: transforms_into CCO:B0066796 ! HELB_HUMAN-Phosphoserine1048 [Term] id: CCO:B0057612 name: NPB_HUMAN def: "Neuropeptide B precursor" [UniProtKB:Q8NG41] synonym: "hPPL7" EXACT [UniProtKB:Q8NG41] synonym: "Preproprotein L7" EXACT [UniProtKB:Q8NG41] xref: EMBL:AAI26129.1 xref: EMBL:AAI26486.1 xref: EMBL:AAP80794.1 xref: EMBL:AAP80795.1 xref: EMBL:BAC07175.1 xref: UniProtKB:A0AUX9 xref: UniProtKB:A6NJD6 xref: UniProtKB:Q8NG41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018830 ! NPB_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057613 name: ELOA3_HUMAN def: "RNA polymerase II transcription factor SIII subunit A3" [UniProtKB:Q8NG57] synonym: "EloA3" EXACT [UniProtKB:Q8NG57] synonym: "Elongin-A3" EXACT [UniProtKB:Q8NG57] synonym: "Transcription elongation factor B polypeptide 3C" EXACT [UniProtKB:Q8NG57] xref: EMBL:BAC01113.1 xref: UniProtKB:Q8NG57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017695 ! TCEB3C_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057614 name: TTL_HUMAN def: "Tubulin--tyrosine ligase" [UniProtKB:Q8NG68] synonym: "EC 6.3.2.25" EXACT [UniProtKB:Q8NG68] synonym: "TTL" EXACT [UniProtKB:Q8NG68] xref: EMBL:AAH36819.1 xref: EMBL:BAC06832.2 xref: EMBL:CAD98091.1 xref: UniProtKB:Q7Z302 xref: UniProtKB:Q8N426 xref: UniProtKB:Q8NG68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020380 ! TTL_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001193 ! tubulin-tyrosine ligase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001276 ! regulation of axon extension [Term] id: CCO:B0057615 name: Q8NG71_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NG71] xref: EMBL:BAC06179.1 xref: UniProtKB:Q8NG71 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057616 name: Q8NG73_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NG73] xref: EMBL:BAC06176.1 xref: UniProtKB:Q8NG73 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057617 name: O2T33_HUMAN def: "Olfactory receptor 2T33" [UniProtKB:Q8NG76] synonym: "Olfactory receptor OR1-56" EXACT [UniProtKB:Q8NG76] xref: EMBL:BAC06173.1 xref: EMBL:CAH71664.1 xref: EMBL:DAA04882.1 xref: UniProtKB:Q8NG76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018969 ! OR2T33_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057618 name: O2T12_HUMAN def: "Olfactory receptor 2T12" [UniProtKB:Q8NG77] synonym: "Olfactory receptor OR1-57" EXACT [UniProtKB:Q8NG77] xref: EMBL:BAC06172.1 xref: EMBL:CAH71665.1 xref: EMBL:DAA04883.1 xref: UniProtKB:Q8NG77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018966 ! OR2T12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057619 name: OR2L5_HUMAN def: "Olfactory receptor 2L5" [UniProtKB:Q8NG80] synonym: "Olfactory receptor OR1-53" EXACT [UniProtKB:Q8NG80] xref: EMBL:BAC06169.1 xref: EMBL:DAA04856.1 xref: UniProtKB:Q6IF04 xref: UniProtKB:Q8NG80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019106 ! OR2L5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057620 name: OR2M7_HUMAN def: "Olfactory receptor 2M7" [UniProtKB:Q8NG81] synonym: "Olfactory receptor OR1-58" EXACT [UniProtKB:Q8NG81] xref: EMBL:BAC06167.1 xref: EMBL:CAH71666.1 xref: EMBL:DAA04884.1 xref: UniProtKB:Q6IEX6 xref: UniProtKB:Q8NG81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019113 ! OR2M7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057621 name: OR2M3_HUMAN def: "Olfactory receptor 2M3" [UniProtKB:Q8NG83] synonym: "Olfactory receptor OR1-54" EXACT [UniProtKB:Q8NG83] xref: EMBL:BAC06165.1 xref: EMBL:CAH71662.1 xref: EMBL:DAA04880.1 xref: UniProtKB:Q6IEY0 xref: UniProtKB:Q8NG83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019110 ! OR2M3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057622 name: O2AK2_HUMAN def: "Olfactory receptor 2AK2" [UniProtKB:Q8NG84] synonym: "Olfactory receptor OR1-47" EXACT [UniProtKB:Q8NG84] xref: EMBL:BAC06164.1 xref: EMBL:DAA04855.1 xref: UniProtKB:Q6IF05 xref: UniProtKB:Q8NG84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018961 ! OR2AK2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057623 name: OR2L3_HUMAN def: "Olfactory receptor 2L3" [UniProtKB:Q8NG85] xref: EMBL:BAC06163.1 xref: UniProtKB:Q8NG85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019105 ! OR2L3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057624 name: Q8NG91_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NG91] xref: EMBL:BAC06154.1 xref: UniProtKB:Q8NG91 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057625 name: O13H1_HUMAN def: "Olfactory receptor 13H1" [UniProtKB:Q8NG92] synonym: "Olfactory receptor ORX-1" EXACT [UniProtKB:Q8NG92] xref: EMBL:AAK95118.1 xref: EMBL:BAC06153.1 xref: EMBL:CAI42350.1 xref: EMBL:DAA04922.1 xref: UniProtKB:Q6IET8 xref: UniProtKB:Q8NG92 xref: UniProtKB:Q96R12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018947 ! OR13H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057626 name: OR7G3_HUMAN def: "Olfactory receptor 7G3" [UniProtKB:Q8NG95] synonym: "OST085" EXACT [UniProtKB:Q8NG95] xref: EMBL:AAK95025.1 xref: EMBL:BAC06147.1 xref: UniProtKB:Q8NG95 xref: UniProtKB:Q96R99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019222 ! OR7G3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057627 name: OR2Z1_HUMAN def: "Olfactory receptor 2Z1" [UniProtKB:Q8NG97] synonym: "Olfactory receptor OR19-4" EXACT [UniProtKB:Q8NG97] xref: EMBL:AAK95104.1 xref: EMBL:BAC06145.1 xref: EMBL:DAA04660.1 xref: UniProtKB:Q6IFK0 xref: UniProtKB:Q8NG97 xref: UniProtKB:Q96R25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019127 ! OR2Z1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057628 name: OR7D4_HUMAN def: "Olfactory receptor 7D4" [UniProtKB:Q8NG98] synonym: "Odorant receptor family subfamily D member 4RT" EXACT [UniProtKB:Q8NG98] synonym: "Olfactory receptor OR19-7" EXACT [UniProtKB:Q8NG98] synonym: "OR19-B" EXACT [UniProtKB:Q8NG98] xref: EMBL:BAC06144.1 xref: EMBL:DAA04624.1 xref: UniProtKB:Q8NG98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019220 ! OR7D4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057629 name: OR7G1_HUMAN def: "Olfactory receptor 7G1" [UniProtKB:Q8NGA0] synonym: "Olfactory receptor 19-15" EXACT [UniProtKB:Q8NGA0] synonym: "OR19-15" EXACT [UniProtKB:Q8NGA0] xref: EMBL:AAK95023.1 xref: EMBL:BAC06141.1 xref: UniProtKB:Q8NGA0 xref: UniProtKB:Q96RA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019221 ! OR7G1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057630 name: OR1M1_HUMAN def: "Olfactory receptor 1M1" [UniProtKB:Q8NGA1] synonym: "Olfactory receptor 19-6" EXACT [UniProtKB:Q8NGA1] synonym: "OR19-6" EXACT [UniProtKB:Q8NGA1] xref: EMBL:AAK95034.1 xref: EMBL:BAC06140.1 xref: UniProtKB:Q8NGA1 xref: UniProtKB:Q96R91 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019076 ! OR1M1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057631 name: OR7A2_HUMAN def: "Putative olfactory receptor 7A2" [UniProtKB:Q8NGA2] xref: EMBL:AAK95029.1 xref: EMBL:BAC06139.1 xref: UniProtKB:Q8NGA2 xref: UniProtKB:Q96R95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019213 ! OR7A2P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057632 name: Q8NGA3_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGA3] xref: EMBL:BAC06138.1 xref: UniProtKB:Q8NGA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057633 name: GPC39_HUMAN def: "Putative G-protein coupled receptor GPCR39" [UniProtKB:Q8NGA4] synonym: "hGPRC39" EXACT [UniProtKB:Q8NGA4] xref: EMBL:BAB89334.1 xref: EMBL:BAC06137.1 xref: UniProtKB:Q8NGA4 xref: UniProtKB:Q8TDT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057634 name: O10H4_HUMAN def: "Olfactory receptor 10H4" [UniProtKB:Q8NGA5] xref: EMBL:AAK95071.1 xref: EMBL:BAC06136.1 xref: UniProtKB:Q8NGA5 xref: UniProtKB:Q96R57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018917 ! OR10H4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057635 name: O10H5_HUMAN def: "Olfactory receptor 10H5" [UniProtKB:Q8NGA6] xref: EMBL:AAK95068.1 xref: EMBL:BAC06135.1 xref: UniProtKB:Q8NGA6 xref: UniProtKB:Q96R60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018918 ! OR10H5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057636 name: O4F17_HUMAN def: "Olfactory receptor 4F17" [UniProtKB:Q8NGA8] xref: EMBL:BAC06132.1 xref: UniProtKB:Q8NGA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018978 ! OR4F17_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057637 name: Q8NGA9_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGA9] xref: EMBL:BAC06131.1 xref: UniProtKB:Q8NGA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057638 name: Q8NGB0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGB0] xref: EMBL:BAC06129.1 xref: UniProtKB:Q8NGB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017969 ! GPR142_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057639 name: OR4C5_HUMAN def: "Olfactory receptor 4C5" [UniProtKB:Q8NGB2] synonym: "Olfactory receptor OR11-99" EXACT [UniProtKB:Q8NGB2] xref: EMBL:BAC06125.1 xref: EMBL:DAA04748.1 xref: UniProtKB:Q6IFB2 xref: UniProtKB:Q8NGB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019136 ! OR4C5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057640 name: OR4S1_HUMAN def: "Olfactory receptor 4S1" [UniProtKB:Q8NGB4] synonym: "Olfactory receptor OR11-100" EXACT [UniProtKB:Q8NGB4] xref: EMBL:BAC06123.1 xref: EMBL:DAA04746.1 xref: UniProtKB:Q6IFB4 xref: UniProtKB:Q8NGB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019173 ! OR4S1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057641 name: Q8NGB5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGB5] xref: EMBL:BAC06121.1 xref: UniProtKB:Q8NGB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057642 name: OR4M2_HUMAN def: "Olfactory receptor 4M2" [UniProtKB:Q8NGB6] xref: EMBL:BAC06118.1 xref: UniProtKB:Q8NGB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019166 ! OR4M2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057643 name: O4F15_HUMAN def: "Olfactory receptor 4F15" [UniProtKB:Q8NGB8] synonym: "Olfactory receptor OR15-14" EXACT [UniProtKB:Q8NGB8] xref: EMBL:AAK95058.1 xref: EMBL:BAC06116.1 xref: EMBL:DAA04803.1 xref: UniProtKB:Q6IF57 xref: UniProtKB:Q8NGB8 xref: UniProtKB:Q96R70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018977 ! OR4F15_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057644 name: OR4F6_HUMAN def: "Olfactory receptor 4F6" [UniProtKB:Q8NGB9] synonym: "Olfactory receptor OR15-15" EXACT [UniProtKB:Q8NGB9] xref: EMBL:BAC06115.1 xref: EMBL:DAA04765.1 xref: UniProtKB:Q6IF95 xref: UniProtKB:Q8NGB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019157 ! OR4F6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057645 name: OR4E2_HUMAN def: "Olfactory receptor 4E2" [UniProtKB:Q8NGC2] synonym: "Olfactory receptor OR14-42" EXACT [UniProtKB:Q8NGC2] xref: EMBL:AAK95066.1 xref: EMBL:BAC06111.1 xref: EMBL:DAA04924.1 xref: UniProtKB:Q6IET6 xref: UniProtKB:Q8NGC2 xref: UniProtKB:Q96R62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019151 ! OR4E2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057646 name: O10G2_HUMAN def: "Olfactory receptor 10G2" [UniProtKB:Q8NGC3] xref: EMBL:BAC06110.1 xref: UniProtKB:Q8NGC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018907 ! OR10G2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057647 name: O10G3_HUMAN def: "Olfactory receptor 10G3" [UniProtKB:Q8NGC4] synonym: "Olfactory receptor OR14-40" EXACT [UniProtKB:Q8NGC4] xref: EMBL:AAK95051.1 xref: EMBL:BAC06109.1 xref: EMBL:DAA04923.1 xref: UniProtKB:Q6IET7 xref: UniProtKB:Q8NGC4 xref: UniProtKB:Q96R77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018908 ! OR10G3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057648 name: OR6J1_HUMAN def: "Olfactory receptor 6J1" [UniProtKB:Q8NGC5] xref: EMBL:BAC06108.1 xref: UniProtKB:Q8NGC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019204 ! OR6J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057649 name: O11H6_HUMAN def: "Olfactory receptor 11H6" [UniProtKB:Q8NGC7] synonym: "Olfactory receptor OR14-35" EXACT [UniProtKB:Q8NGC7] xref: EMBL:BAC06106.1 xref: EMBL:DAA04852.1 xref: UniProtKB:Q6IF08 xref: UniProtKB:Q8NGC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018935 ! OR11H6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057650 name: O11H7_HUMAN def: "Olfactory receptor 11H7" [UniProtKB:Q8NGC8] synonym: "Olfactory receptor OR14-32" EXACT [UniProtKB:Q8NGC8] xref: EMBL:BAC06105.1 xref: UniProtKB:Q8NGC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018936 ! OR11H7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057651 name: O11H4_HUMAN def: "Olfactory receptor 11H4" [UniProtKB:Q8NGC9] synonym: "Olfactory receptor OR14-36" EXACT [UniProtKB:Q8NGC9] xref: EMBL:BAC06104.1 xref: EMBL:DAA04853.1 xref: UniProtKB:Q6IF07 xref: UniProtKB:Q8NGC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018934 ! OR11H4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057652 name: OR4M1_HUMAN def: "Olfactory receptor 4M1" [UniProtKB:Q8NGD0] xref: EMBL:BAC06103.1 xref: UniProtKB:Q8NGD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019165 ! OR4M1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057653 name: OR4N2_HUMAN def: "Olfactory receptor 4N2" [UniProtKB:Q8NGD1] synonym: "Olfactory receptor OR14-8" EXACT [UniProtKB:Q8NGD1] xref: EMBL:BAC06102.1 xref: EMBL:DAA04871.1 xref: UniProtKB:Q6IEY9 xref: UniProtKB:Q8NGD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019167 ! OR4N2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057654 name: OR4K2_HUMAN def: "Olfactory receptor 4K2" [UniProtKB:Q8NGD2] synonym: "Olfactory receptor OR14-15" EXACT [UniProtKB:Q8NGD2] xref: EMBL:BAC06101.1 xref: EMBL:DAA04755.1 xref: UniProtKB:Q6IFA5 xref: UniProtKB:Q8NGD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019159 ! OR4K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057655 name: OR4K5_HUMAN def: "Olfactory receptor 4K5" [UniProtKB:Q8NGD3] synonym: "Olfactory receptor OR14-16" EXACT [UniProtKB:Q8NGD3] xref: EMBL:BAC06100.1 xref: EMBL:DAA04753.1 xref: UniProtKB:Q6IFA7 xref: UniProtKB:Q8NGD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019161 ! OR4K5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057656 name: OR4K1_HUMAN def: "Olfactory receptor 4K1" [UniProtKB:Q8NGD4] xref: EMBL:AAK95055.1 xref: EMBL:BAC06099.1 xref: UniProtKB:Q8NGD4 xref: UniProtKB:Q96R73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019158 ! OR4K1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057657 name: OR4KE_HUMAN def: "Olfactory receptor 4K14" [UniProtKB:Q8NGD5] synonym: "Olfactory receptor OR14-22" EXACT [UniProtKB:Q8NGD5] xref: EMBL:AAK95057.1 xref: EMBL:BAC06098.1 xref: EMBL:DAA04919.1 xref: UniProtKB:Q6IEU1 xref: UniProtKB:Q8NGD5 xref: UniProtKB:Q96R71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019163 ! OR4K14_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057658 name: O10AD_HUMAN def: "Olfactory receptor 10AD1" [UniProtKB:Q8NGE0] synonym: "Olfactory receptor OR12-1" EXACT [UniProtKB:Q8NGE0] xref: EMBL:BAC06090.1 xref: EMBL:DAA04752.1 xref: UniProtKB:Q6IFA8 xref: UniProtKB:Q8NGE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018903 ! OR10AD1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057659 name: OR6C4_HUMAN def: "Olfactory receptor 6C4" [UniProtKB:Q8NGE1] xref: EMBL:BAC06087.1 xref: UniProtKB:Q8NGE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019201 ! OR6C4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057660 name: O2AP1_HUMAN def: "Olfactory receptor 2AP1" [UniProtKB:Q8NGE2] synonym: "Olfactory receptor OR12-9" EXACT [UniProtKB:Q8NGE2] xref: EMBL:BAC06086.1 xref: EMBL:DAA04658.1 xref: UniProtKB:Q8NGE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018962 ! OR2AP1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057661 name: O10A7_HUMAN def: "Olfactory receptor 10A7" [UniProtKB:Q8NGE5] synonym: "Olfactory receptor OR12-6" EXACT [UniProtKB:Q8NGE5] xref: EMBL:AAK95111.1 xref: EMBL:BAC06082.1 xref: EMBL:DAA04725.1 xref: UniProtKB:Q6IFD5 xref: UniProtKB:Q8NGE5 xref: UniProtKB:Q96R19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018902 ! OR10A7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057662 name: Q8NGE6_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGE6] xref: EMBL:BAC06081.1 xref: UniProtKB:Q8NGE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057663 name: OR4D9_HUMAN def: "Olfactory receptor 4D9" [UniProtKB:Q8NGE8] synonym: "Olfactory receptor OR11-253" EXACT [UniProtKB:Q8NGE8] xref: EMBL:BAC06079.1 xref: EMBL:DAA04707.1 xref: UniProtKB:Q6IFF3 xref: UniProtKB:Q8NGE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019147 ! OR4D9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057664 name: Q8NGF2_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGF2] xref: EMBL:BAC06074.1 xref: UniProtKB:Q8NGF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057665 name: O51D1_HUMAN def: "Olfactory receptor 51D1" [UniProtKB:Q8NGF3] synonym: "Olfactory receptor OR11-14" EXACT [UniProtKB:Q8NGF3] xref: EMBL:BAC06073.1 xref: EMBL:DAA04768.1 xref: UniProtKB:Q8NGF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018987 ! OR51D1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057666 name: O10W1_HUMAN def: "Olfactory receptor 10W1" [UniProtKB:Q8NGF6] synonym: "Olfactory receptor OR11-236" EXACT [UniProtKB:Q8NGF6] xref: EMBL:AAQ88618.1 xref: EMBL:BAC06068.1 xref: EMBL:DAA04888.1 xref: UniProtKB:Q6UXQ2 xref: UniProtKB:Q8NGF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018929 ! OR10W1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057667 name: OR4B1_HUMAN def: "Olfactory receptor 4B1" [UniProtKB:Q8NGF8] synonym: "Olfactory receptor OR11-106" EXACT [UniProtKB:Q8NGF8] synonym: "OST208" EXACT [UniProtKB:Q8NGF8] xref: EMBL:AAK95064.1 xref: EMBL:BAC06066.1 xref: EMBL:DAA04785.1 xref: UniProtKB:Q6IF75 xref: UniProtKB:Q8NGF8 xref: UniProtKB:Q96R64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019134 ! OR4B1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057668 name: OR4X2_HUMAN def: "Olfactory receptor 4X2" [UniProtKB:Q8NGF9] synonym: "Olfactory receptor OR11-105" EXACT [UniProtKB:Q8NGF9] xref: EMBL:AAK95065.1 xref: EMBL:BAC06065.1 xref: EMBL:DAA04787.1 xref: UniProtKB:Q6IF73 xref: UniProtKB:Q8NGF9 xref: UniProtKB:Q96R63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019176 ! OR4X2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057669 name: OR8J3_HUMAN def: "Olfactory receptor 8J3" [UniProtKB:Q8NGG0] xref: EMBL:AAK95001.1 xref: EMBL:BAC06060.1 xref: UniProtKB:Q8NGG0 xref: UniProtKB:Q96RC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019231 ! OR8J3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057670 name: OR8J2_HUMAN def: "Olfactory receptor 8J2" [UniProtKB:Q8NGG1] xref: EMBL:BAC06058.1 xref: UniProtKB:Q8NGG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019230 ! OR8J2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057671 name: OR8K1_HUMAN def: "Olfactory receptor 8K1" [UniProtKB:Q8NGG5] synonym: "Olfactory receptor OR11-182" EXACT [UniProtKB:Q8NGG5] xref: EMBL:AAK95002.1 xref: EMBL:BAC06054.1 xref: EMBL:DAA04737.1 xref: UniProtKB:Q6IFC3 xref: UniProtKB:Q8NGG5 xref: UniProtKB:Q96RC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019232 ! OR8K1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057672 name: OR8BC_HUMAN def: "Olfactory receptor 8B12" [UniProtKB:Q8NGG6] synonym: "Olfactory receptor OR11-317" EXACT [UniProtKB:Q8NGG6] xref: EMBL:AAK94996.1 xref: EMBL:BAC06053.1 xref: EMBL:DAA04892.1 xref: UniProtKB:Q6IEW8 xref: UniProtKB:Q8NGG6 xref: UniProtKB:Q96RC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019226 ! OR8B12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057673 name: OR8B3_HUMAN def: "Olfactory receptor 8B3" [UniProtKB:Q8NGG8] xref: EMBL:BAC06046.1 xref: EMBL:BAC06049.1 xref: UniProtKB:Q8NGG8 xref: UniProtKB:Q8NGH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019224 ! OR8B3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057674 name: Q8NGG9_HUMAN def: "Seven transmembrane helix receptor (Olfactory receptor OR11-310)" [UniProtKB:Q8NGG9] xref: EMBL:BAC06048.1 xref: EMBL:DAA04601.1 xref: UniProtKB:Q8NGG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057675 name: Q8NGH2_HUMAN def: "Seven transmembrane helix receptor (Olfactory receptor, family 8, subfamily B, member 2) (Olfactory receptor OR11-309)" [UniProtKB:Q8NGH2] xref: EMBL:BAC06045.1 xref: EMBL:DAA04898.1 xref: EMBL:EAW67580.1 xref: UniProtKB:Q8NGH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019223 ! OR8B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057676 name: O52E4_HUMAN def: "Olfactory receptor 52E4" [UniProtKB:Q8NGH9] xref: EMBL:BAC06036.1 xref: UniProtKB:Q8NGH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019009 ! OR52E4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057677 name: O52N2_HUMAN def: "Olfactory receptor 52N2" [UniProtKB:Q8NGI0] xref: EMBL:BAC06035.1 xref: UniProtKB:Q8NGI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019019 ! OR52N2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057678 name: O56B2_HUMAN def: "Putative olfactory receptor 56B2" [UniProtKB:Q8NGI1] xref: EMBL:BAC06033.1 xref: UniProtKB:Q8NGI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019027 ! OR56B2P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057679 name: O52N4_HUMAN def: "Olfactory receptor 52N4" [UniProtKB:Q8NGI2] synonym: "Olfactory receptor OR11-64" EXACT [UniProtKB:Q8NGI2] xref: EMBL:BAC06032.1 xref: EMBL:DAA04783.1 xref: UniProtKB:Q6IF77 xref: UniProtKB:Q8NGI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019020 ! OR52N4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057680 name: O56B1_HUMAN def: "Olfactory receptor 56B1" [UniProtKB:Q8NGI3] synonym: "Olfactory receptor OR11-65" EXACT [UniProtKB:Q8NGI3] xref: EMBL:BAC06031.1 xref: EMBL:DAA04784.1 xref: UniProtKB:Q6IF76 xref: UniProtKB:Q8NGI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019026 ! OR56B1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057681 name: OR4DB_HUMAN def: "Olfactory receptor 4D11" [UniProtKB:Q8NGI4] xref: EMBL:BAC06029.1 xref: UniProtKB:Q8NGI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019149 ! OR4D11_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057682 name: Q8NGI5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGI5] xref: EMBL:BAC06028.1 xref: UniProtKB:Q8NGI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057683 name: OR4DA_HUMAN def: "Olfactory receptor 4D10" [UniProtKB:Q8NGI6] synonym: "Olfactory receptor OR11-251" EXACT [UniProtKB:Q8NGI6] xref: EMBL:BAC06027.1 xref: EMBL:DAA04709.1 xref: UniProtKB:Q8NGI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019148 ! OR4D10_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057684 name: O10V1_HUMAN def: "Olfactory receptor 10V1" [UniProtKB:Q8NGI7] xref: EMBL:AAK95078.1 xref: EMBL:BAC06026.1 xref: UniProtKB:Q8NGI7 xref: UniProtKB:Q96R50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018928 ! OR10V1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057685 name: O5AN1_HUMAN def: "Olfactory receptor 5AN1" [UniProtKB:Q8NGI8] synonym: "Olfactory receptor OR11-244" EXACT [UniProtKB:Q8NGI8] xref: EMBL:BAC06025.1 xref: EMBL:DAA04906.1 xref: UniProtKB:Q6IEV4 xref: UniProtKB:Q8NGI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019030 ! OR5AN1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057686 name: OR5A2_HUMAN def: "Olfactory receptor 5A2" [UniProtKB:Q8NGI9] xref: EMBL:AAK95014.1 xref: EMBL:BAC06024.1 xref: UniProtKB:Q8NGI9 xref: UniProtKB:Q96RB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019178 ! OR5A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057687 name: OR5A1_HUMAN def: "Olfactory receptor 5A1" [UniProtKB:Q8NGJ0] synonym: "OST181" EXACT [UniProtKB:Q8NGJ0] xref: EMBL:AAK95013.1 xref: EMBL:BAC06023.1 xref: UniProtKB:Q8NGJ0 xref: UniProtKB:Q96RB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019177 ! OR5A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057688 name: OR4D6_HUMAN def: "Olfactory receptor 4D6" [UniProtKB:Q8NGJ1] synonym: "Olfactory receptor OR11-250" EXACT [UniProtKB:Q8NGJ1] xref: EMBL:AAK95054.1 xref: EMBL:BAC06022.1 xref: EMBL:DAA04705.1 xref: UniProtKB:Q6IFF5 xref: UniProtKB:Q8NGJ1 xref: UniProtKB:Q96R74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019146 ! OR4D6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057689 name: O52E1_HUMAN def: "Olfactory receptor 52E1" [UniProtKB:Q8NGJ3] xref: EMBL:BAC06020.1 xref: UniProtKB:Q8NGJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019007 ! OR52E1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057690 name: O52E2_HUMAN def: "Olfactory receptor 52E2" [UniProtKB:Q8NGJ4] xref: EMBL:BAC06019.1 xref: UniProtKB:Q8NGJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019008 ! OR52E2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057691 name: O51L1_HUMAN def: "Olfactory receptor 51L1" [UniProtKB:Q8NGJ5] xref: EMBL:BAC06018.1 xref: UniProtKB:Q8NGJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018997 ! OR51L1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057692 name: O51A4_HUMAN def: "Olfactory receptor 51A4" [UniProtKB:Q8NGJ6] xref: EMBL:BAC06017.1 xref: UniProtKB:Q8NGJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018981 ! OR51A4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057693 name: O51A2_HUMAN def: "Olfactory receptor 51A2" [UniProtKB:Q8NGJ7] xref: EMBL:BAC06016.1 xref: UniProtKB:Q8NGJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018980 ! OR51A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057694 name: O51S1_HUMAN def: "Olfactory receptor 51S1" [UniProtKB:Q8NGJ8] xref: EMBL:BAC06015.1 xref: UniProtKB:Q8NGJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019000 ! OR51S1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057695 name: O51G2_HUMAN def: "Olfactory receptor 51G2" [UniProtKB:Q8NGK0] xref: EMBL:BAC06013.1 xref: UniProtKB:Q8NGK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018992 ! OR51G2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057696 name: O51G1_HUMAN def: "Olfactory receptor 51G1" [UniProtKB:Q8NGK1] xref: EMBL:BAC06012.1 xref: UniProtKB:Q8NGK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018991 ! OR51G1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057697 name: O52B4_HUMAN def: "Olfactory receptor 52B4" [UniProtKB:Q8NGK2] synonym: "Olfactory receptor OR11-3" EXACT [UniProtKB:Q8NGK2] xref: EMBL:BAC06011.1 xref: EMBL:DAA04654.1 xref: EMBL:EAW68847.1 xref: UniProtKB:A6NP68 xref: UniProtKB:Q6IFK6 xref: UniProtKB:Q8NGK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019005 ! OR52B4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057698 name: O52K2_HUMAN def: "Olfactory receptor 52K2" [UniProtKB:Q8NGK3] xref: EMBL:BAC06010.1 xref: UniProtKB:Q8NGK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019016 ! OR52K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057699 name: O52K1_HUMAN def: "Olfactory receptor 52K1" [UniProtKB:Q8NGK4] xref: EMBL:BAC06009.1 xref: UniProtKB:Q8NGK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019015 ! OR52K1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057700 name: O52M1_HUMAN def: "Olfactory receptor 52M1" [UniProtKB:Q8NGK5] synonym: "Olfactory receptor OR11-11" EXACT [UniProtKB:Q8NGK5] xref: EMBL:BAC06008.1 xref: EMBL:DAA04770.1 xref: UniProtKB:Q8NGK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019017 ! OR52M1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057701 name: O52I1_HUMAN def: "Olfactory receptor 52I1" [UniProtKB:Q8NGK6] synonym: "Olfactory receptor OR11-13" EXACT [UniProtKB:Q8NGK6] xref: EMBL:BAC06007.1 xref: EMBL:DAA04769.1 xref: UniProtKB:Q6IF91 xref: UniProtKB:Q8NGK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019013 ! OR52I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057702 name: Q8NGK8_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGK8] xref: EMBL:BAC06004.1 xref: UniProtKB:Q8NGK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057703 name: OR5DG_HUMAN def: "Olfactory receptor 5D16" [UniProtKB:Q8NGK9] synonym: "Olfactory receptor OR11-154" EXACT [UniProtKB:Q8NGK9] xref: EMBL:AAK95009.1 xref: EMBL:BAC06003.1 xref: EMBL:DAA04795.1 xref: UniProtKB:Q6IF65 xref: UniProtKB:Q8NGK9 xref: UniProtKB:Q96RB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019183 ! OR5D16_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057704 name: OR5DI_HUMAN def: "Olfactory receptor 5D18" [UniProtKB:Q8NGL1] synonym: "Olfactory receptor OR11-143" EXACT [UniProtKB:Q8NGL1] xref: EMBL:AAK95010.1 xref: EMBL:BAC06001.1 xref: EMBL:DAA04793.1 xref: UniProtKB:Q6IF67 xref: UniProtKB:Q8NGL1 xref: UniProtKB:Q96RB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019184 ! OR5D18_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057705 name: OR5DE_HUMAN def: "Olfactory receptor 5D14" [UniProtKB:Q8NGL3] synonym: "Olfactory receptor OR11-141" EXACT [UniProtKB:Q8NGL3] xref: EMBL:AAK95008.1 xref: EMBL:BAC05999.1 xref: EMBL:DAA04791.1 xref: UniProtKB:Q6IF69 xref: UniProtKB:Q8NGL3 xref: UniProtKB:Q96RB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019182 ! OR5D14_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057706 name: OR5DD_HUMAN def: "Olfactory receptor 5D13" [UniProtKB:Q8NGL4] synonym: "Olfactory receptor OR11-142" EXACT [UniProtKB:Q8NGL4] synonym: "Olfactory receptor OR11-148" EXACT [UniProtKB:Q8NGL4] xref: EMBL:BAC05998.1 xref: EMBL:DAA04731.1 xref: EMBL:DAA04792.1 xref: UniProtKB:Q6IF68 xref: UniProtKB:Q6IFC9 xref: UniProtKB:Q8NGL4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019181 ! OR5D13_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057707 name: Q8NGL5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGL5] xref: EMBL:BAC05997.1 xref: UniProtKB:Q8NGL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057708 name: O4A15_HUMAN def: "Olfactory receptor 4A15" [UniProtKB:Q8NGL6] synonym: "Olfactory receptor OR11-118" EXACT [UniProtKB:Q8NGL6] xref: EMBL:AAK95063.1 xref: EMBL:BAC05996.1 xref: EMBL:DAA04646.1 xref: UniProtKB:Q6IFL4 xref: UniProtKB:Q8NGL6 xref: UniProtKB:Q96R65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018972 ! OR4A15_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057709 name: OR4P4_HUMAN def: "Olfactory receptor 4P4" [UniProtKB:Q8NGL7] xref: EMBL:BAC05995.1 xref: UniProtKB:Q8NGL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019170 ! OR4P4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057710 name: OR4CG_HUMAN def: "Olfactory receptor 4C16" [UniProtKB:Q8NGL9] synonym: "Olfactory receptor OR11-135" EXACT [UniProtKB:Q8NGL9] xref: EMBL:BAC05993.1 xref: EMBL:DAA04902.1 xref: UniProtKB:Q6IEV8 xref: UniProtKB:Q8NGL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019142 ! OR4C16_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057711 name: Q8NGM0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGM0] xref: EMBL:BAC05992.1 xref: UniProtKB:Q8NGM0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057712 name: OR4CF_HUMAN def: "Olfactory receptor 4C15" [UniProtKB:Q8NGM1] synonym: "Olfactory receptor OR11-127" EXACT [UniProtKB:Q8NGM1] synonym: "Olfactory receptor OR11-134" EXACT [UniProtKB:Q8NGM1] xref: EMBL:BAC05991.1 xref: EMBL:DAA04717.1 xref: EMBL:DAA04718.1 xref: UniProtKB:Q6IFE2 xref: UniProtKB:Q8NGM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019141 ! OR4C15_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057713 name: Q8NGM3_HUMAN def: "Seven transmembrane helix receptor (HCG1641819)" [UniProtKB:Q8NGM3] xref: EMBL:BAC05989.1 xref: EMBL:EAW68644.1 xref: UniProtKB:Q8NGM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021235 ! OR5E1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057714 name: Q8NGM4_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGM4] xref: EMBL:BAC05986.1 xref: UniProtKB:Q8NGM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057715 name: Q8NGM5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGM5] xref: EMBL:BAC05985.1 xref: UniProtKB:Q8NGM5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057716 name: Q8NGM6_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGM6] xref: EMBL:BAC05984.1 xref: UniProtKB:Q8NGM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057717 name: Q8NGM7_HUMAN def: "Seven transmembrane helix receptor (Olfactory receptor, family 52, subfamily B, member 2) (Olfactory receptor OR11-70)" [UniProtKB:Q8NGM7] xref: EMBL:AAI36733.1 xref: EMBL:AAI36734.1 xref: EMBL:BAC05983.1 xref: EMBL:DAA04722.1 xref: EMBL:EAW68744.1 xref: UniProtKB:Q8NGM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021236 ! OR52B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057718 name: OR4D5_HUMAN def: "Olfactory receptor 4D5" [UniProtKB:Q8NGN0] synonym: "Olfactory receptor OR11-276" EXACT [UniProtKB:Q8NGN0] xref: EMBL:BAC05980.1 xref: EMBL:DAA04714.1 xref: UniProtKB:Q6IFE6 xref: UniProtKB:Q8NGN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019145 ! OR4D5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057719 name: OR6T1_HUMAN def: "Olfactory receptor 6T1" [UniProtKB:Q8NGN1] xref: EMBL:BAC05979.1 xref: UniProtKB:Q8NGN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019210 ! OR6T1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057720 name: O10G4_HUMAN def: "Olfactory receptor 10G4" [UniProtKB:Q8NGN3] synonym: "Olfactory receptor OR11-278" EXACT [UniProtKB:Q8NGN3] xref: EMBL:BAC05977.1 xref: EMBL:DAA04900.1 xref: UniProtKB:Q6IEW0 xref: UniProtKB:Q8NGN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018909 ! OR10G4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057721 name: O10G9_HUMAN def: "Olfactory receptor 10G9" [UniProtKB:Q8NGN4] xref: EMBL:BAC05976.1 xref: UniProtKB:Q8NGN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018913 ! OR10G9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057722 name: O10G8_HUMAN def: "Olfactory receptor 10G8" [UniProtKB:Q8NGN5] synonym: "Olfactory receptor OR11-282" EXACT [UniProtKB:Q8NGN5] xref: EMBL:BAC05975.1 xref: EMBL:DAA04908.1 xref: UniProtKB:Q6IEV2 xref: UniProtKB:Q8NGN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018912 ! OR10G8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057723 name: O10G7_HUMAN def: "Olfactory receptor 10G7" [UniProtKB:Q8NGN6] xref: EMBL:BAC05974.1 xref: UniProtKB:Q8NGN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018911 ! OR10G7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057724 name: O10D4_HUMAN def: "Putative olfactory receptor 10D4" [UniProtKB:Q8NGN7] xref: EMBL:BAC05973.1 xref: UniProtKB:Q8NGN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018906 ! OR10D4P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057725 name: OR4A4_HUMAN def: "Putative olfactory receptor 4A4" [UniProtKB:Q8NGN8] synonym: "Olfactory receptor OR11-107" EXACT [UniProtKB:Q8NGN8] xref: EMBL:AAK95062.1 xref: EMBL:BAC05972.1 xref: EMBL:DAA04777.1 xref: UniProtKB:Q6IF83 xref: UniProtKB:Q8NGN8 xref: UniProtKB:Q96R66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019131 ! OR4A4P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057726 name: Q8NGN9_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGN9] xref: EMBL:BAC05971.1 xref: UniProtKB:Q8NGN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057727 name: OR4CD_HUMAN def: "Olfactory receptor 4C13" [UniProtKB:Q8NGP0] synonym: "Olfactory receptor OR11-260" EXACT [UniProtKB:Q8NGP0] xref: EMBL:AAK95060.1 xref: EMBL:BAC05970.1 xref: EMBL:DAA04812.1 xref: UniProtKB:A6NJJ3 xref: UniProtKB:Q6IF48 xref: UniProtKB:Q8NGP0 xref: UniProtKB:Q96R68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019140 ! OR4C13_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057728 name: OR8J1_HUMAN def: "Olfactory receptor 8J1" [UniProtKB:Q8NGP2] synonym: "Olfactory receptor OR11-183" EXACT [UniProtKB:Q8NGP2] xref: EMBL:AAK95000.1 xref: EMBL:BAC05968.1 xref: EMBL:DAA04738.1 xref: UniProtKB:Q6IFC2 xref: UniProtKB:Q8NGP2 xref: UniProtKB:Q96RC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019229 ! OR8J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057729 name: OR5M9_HUMAN def: "Olfactory receptor 5M9" [UniProtKB:Q8NGP3] synonym: "Olfactory receptor OR11-190" EXACT [UniProtKB:Q8NGP3] xref: EMBL:AAK95004.1 xref: EMBL:BAC05967.1 xref: EMBL:DAA04895.1 xref: UniProtKB:Q6IEW5 xref: UniProtKB:Q8NGP3 xref: UniProtKB:Q96RB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019190 ! OR5M9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057730 name: OR5M3_HUMAN def: "Olfactory receptor 5M3" [UniProtKB:Q8NGP4] synonym: "Olfactory receptor OR11-191" EXACT [UniProtKB:Q8NGP4] xref: EMBL:AAK95003.1 xref: EMBL:BAC05966.1 xref: EMBL:DAA04896.1 xref: UniProtKB:Q6IEW4 xref: UniProtKB:Q8NGP4 xref: UniProtKB:Q96RC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019188 ! OR5M3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057731 name: Q8NGP5_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGP5] xref: EMBL:BAC05965.1 xref: UniProtKB:Q8NGP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057732 name: OR5M8_HUMAN def: "Olfactory receptor 5M8" [UniProtKB:Q8NGP6] synonym: "Olfactory receptor OR11-194" EXACT [UniProtKB:Q8NGP6] xref: EMBL:AAK95005.1 xref: EMBL:BAC05964.1 xref: EMBL:DAA04897.1 xref: UniProtKB:Q6IEW3 xref: UniProtKB:Q8NGP6 xref: UniProtKB:Q96RB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019189 ! OR5M8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057733 name: Q8NGP7_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGP7] xref: EMBL:BAC05963.1 xref: UniProtKB:Q8NGP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057734 name: OR5M1_HUMAN def: "Olfactory receptor 5M1" [UniProtKB:Q8NGP8] synonym: "Olfactory receptor OR11-208" EXACT [UniProtKB:Q8NGP8] synonym: "OST050" EXACT [UniProtKB:Q8NGP8] xref: EMBL:AAK95007.1 xref: EMBL:BAC05962.1 xref: EMBL:DAA04800.1 xref: UniProtKB:Q6IF60 xref: UniProtKB:Q8NGP8 xref: UniProtKB:Q96RB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019187 ! OR5M1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057735 name: OR6Q1_HUMAN def: "Olfactory receptor 6Q1" [UniProtKB:Q8NGQ2] xref: EMBL:AAK95094.1 xref: EMBL:BAC05958.1 xref: UniProtKB:Q8NGQ2 xref: UniProtKB:Q96R34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019209 ! OR6Q1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057736 name: O10Q1_HUMAN def: "Olfactory receptor 10Q1" [UniProtKB:Q8NGQ4] xref: EMBL:BAC05956.1 xref: UniProtKB:Q8NGQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018926 ! OR10Q1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057737 name: OR9Q1_HUMAN def: "Olfactory receptor 9Q1" [UniProtKB:Q8NGQ5] xref: EMBL:AAI10820.1 xref: EMBL:AAK95017.1 xref: EMBL:BAC05955.1 xref: UniProtKB:Q2TAN3 xref: UniProtKB:Q8NGQ5 xref: UniProtKB:Q96RA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019239 ! OR9Q1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057738 name: Q8NGQ7_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGQ7] xref: EMBL:BAC05953.1 xref: UniProtKB:Q8NGQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057739 name: OR1K1_HUMAN def: "Olfactory receptor 1K1" [UniProtKB:Q8NGR3] xref: EMBL:AAK95107.1 xref: EMBL:BAC05947.1 xref: EMBL:CAI94957.1 xref: UniProtKB:Q4VXB7 xref: UniProtKB:Q8NGR3 xref: UniProtKB:Q96R23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019072 ! OR1K1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057740 name: OR1L4_HUMAN def: "Olfactory receptor 1L4" [UniProtKB:Q8NGR5] synonym: "Olfactory receptor 9-E" EXACT [UniProtKB:Q8NGR5] synonym: "OR9-E" EXACT [UniProtKB:Q8NGR5] synonym: "OST046" EXACT [UniProtKB:Q8NGR5] xref: EMBL:AAK95047.1 xref: EMBL:BAC05945.1 xref: UniProtKB:Q8NGR5 xref: UniProtKB:Q96R81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019074 ! OR1L4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057741 name: OR1B1_HUMAN def: "Olfactory receptor 1B1" [UniProtKB:Q8NGR6] synonym: "Olfactory receptor 9-B" EXACT [UniProtKB:Q8NGR6] synonym: "Olfactory receptor OR9-26" EXACT [UniProtKB:Q8NGR6] synonym: "OR9-B" EXACT [UniProtKB:Q8NGR6] xref: EMBL:BAC05944.1 xref: EMBL:CAI16289.1 xref: EMBL:DAA04627.1 xref: UniProtKB:Q6IFN3 xref: UniProtKB:Q8NGR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019059 ! OR1B1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057742 name: OR1L8_HUMAN def: "Olfactory receptor 1L8" [UniProtKB:Q8NGR8] synonym: "Olfactory receptor OR9-24" EXACT [UniProtKB:Q8NGR8] xref: EMBL:AAK95049.1 xref: EMBL:BAC05942.1 xref: EMBL:DAA04845.1 xref: UniProtKB:Q6IF15 xref: UniProtKB:Q8NGR8 xref: UniProtKB:Q96R79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019075 ! OR1L8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057743 name: OR1N1_HUMAN def: "Olfactory receptor 1N1" [UniProtKB:Q8NGS0] synonym: "Olfactory receptor 1-26" EXACT [UniProtKB:Q8NGS0] synonym: "Olfactory receptor 1N3" EXACT [UniProtKB:Q8NGS0] synonym: "Olfactory receptor OR9-22" EXACT [UniProtKB:Q8NGS0] synonym: "OR1-26" EXACT [UniProtKB:Q8NGS0] xref: EMBL:AAC39612.1 xref: EMBL:AAK95032.1 xref: EMBL:BAC05940.1 xref: EMBL:DAA04844.1 xref: UniProtKB:O43870 xref: UniProtKB:Q6IF16 xref: UniProtKB:Q8NGS0 xref: UniProtKB:Q96R93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019077 ! OR1N1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057744 name: OR1J4_HUMAN def: "Olfactory receptor 1J4" [UniProtKB:Q8NGS1] synonym: "HTPCRX01" EXACT [UniProtKB:Q8NGS1] synonym: "Olfactory receptor OR9-21" EXACT [UniProtKB:Q8NGS1] xref: EMBL:AAK95038.1 xref: EMBL:BAC05939.1 xref: EMBL:DAA04867.1 xref: UniProtKB:Q6IEZ3 xref: UniProtKB:Q8NGS1 xref: UniProtKB:Q96R89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019071 ! OR1J4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057745 name: OR1J2_HUMAN def: "Olfactory receptor 1J2" [UniProtKB:Q8NGS2] synonym: "HSA5" EXACT [UniProtKB:Q8NGS2] synonym: "HTPCRX15" EXACT [UniProtKB:Q8NGS2] synonym: "Olfactory receptor OR9-19" EXACT [UniProtKB:Q8NGS2] synonym: "OST044" EXACT [UniProtKB:Q8NGS2] xref: EMBL:AAF40352.1 xref: EMBL:AAK95037.1 xref: EMBL:BAC05938.1 xref: EMBL:DAA04846.1 xref: UniProtKB:Q6IF14 xref: UniProtKB:Q8NGS2 xref: UniProtKB:Q96R90 xref: UniProtKB:Q9NZP1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019070 ! OR1J2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057746 name: OR1J1_HUMAN def: "Olfactory receptor 1J1" [UniProtKB:Q8NGS3] synonym: "Olfactory receptor OR9-18" EXACT [UniProtKB:Q8NGS3] xref: EMBL:AAK95039.1 xref: EMBL:BAC05937.1 xref: EMBL:DAA04850.1 xref: UniProtKB:Q6IF10 xref: UniProtKB:Q8NGS3 xref: UniProtKB:Q96R88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019069 ! OR1J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057747 name: O13F1_HUMAN def: "Olfactory receptor 13F1" [UniProtKB:Q8NGS4] synonym: "Olfactory receptor OR9-6" EXACT [UniProtKB:Q8NGS4] xref: EMBL:BAC05936.1 xref: EMBL:CAH72409.1 xref: EMBL:DAA04810.1 xref: UniProtKB:Q6IF50 xref: UniProtKB:Q8NGS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018945 ! OR13F1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057748 name: O13C4_HUMAN def: "Olfactory receptor 13C4" [UniProtKB:Q8NGS5] synonym: "Olfactory receptor OR9-7" EXACT [UniProtKB:Q8NGS5] xref: EMBL:AAK95087.1 xref: EMBL:BAC05935.1 xref: EMBL:CAH72410.1 xref: EMBL:DAA04809.1 xref: UniProtKB:Q6IF51 xref: UniProtKB:Q8NGS5 xref: UniProtKB:Q96R41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018941 ! OR13C4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057749 name: O13C8_HUMAN def: "Olfactory receptor 13C8" [UniProtKB:Q8NGS7] xref: EMBL:AAK95084.1 xref: EMBL:BAC05933.1 xref: EMBL:CAH72412.1 xref: UniProtKB:Q5VVG0 xref: UniProtKB:Q8NGS7 xref: UniProtKB:Q96R44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018943 ! OR13C8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057750 name: O13C5_HUMAN def: "Olfactory receptor 13C5" [UniProtKB:Q8NGS8] synonym: "Olfactory receptor OR9-11" EXACT [UniProtKB:Q8NGS8] xref: EMBL:BAC05932.1 xref: EMBL:CAH72414.1 xref: EMBL:DAA04807.1 xref: UniProtKB:Q6IF53 xref: UniProtKB:Q8NGS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018942 ! OR13C5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057751 name: O13C2_HUMAN def: "Olfactory receptor 13C2" [UniProtKB:Q8NGS9] synonym: "Olfactory receptor OR9-12" EXACT [UniProtKB:Q8NGS9] xref: EMBL:BAC05931.1 xref: EMBL:CAH73574.1 xref: EMBL:DAA04806.1 xref: UniProtKB:Q6IF54 xref: UniProtKB:Q8NGS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018940 ! OR13C2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057752 name: O13C9_HUMAN def: "Olfactory receptor 13C9" [UniProtKB:Q8NGT0] xref: EMBL:BAC05930.1 xref: UniProtKB:Q8NGT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018944 ! OR13C9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057753 name: OR2K1_HUMAN def: "Olfactory receptor 2K2" [UniProtKB:Q8NGT1] synonym: "HTPCRH06" EXACT [UniProtKB:Q8NGT1] xref: EMBL:AAI11087.1 xref: EMBL:BAC05929.1 xref: EMBL:CAH73239.1 xref: UniProtKB:Q2TA61 xref: UniProtKB:Q5VYK4 xref: UniProtKB:Q8NGT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019103 ! OR2K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057754 name: O13J1_HUMAN def: "Olfactory receptor 13J1" [UniProtKB:Q8NGT2] synonym: "Olfactory receptor OR9-2" EXACT [UniProtKB:Q8NGT2] xref: EMBL:AAK95088.1 xref: EMBL:BAC05928.1 xref: EMBL:CAI10998.1 xref: EMBL:DAA04840.1 xref: UniProtKB:Q6IF20 xref: UniProtKB:Q8NGT2 xref: UniProtKB:Q96R40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018948 ! OR13J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057755 name: OR9A2_HUMAN def: "Olfactory receptor 9A2" [UniProtKB:Q8NGT5] synonym: "Olfactory receptor OR7-2" EXACT [UniProtKB:Q8NGT5] xref: EMBL:BAC05919.1 xref: EMBL:BAC06092.1 xref: EMBL:DAA04789.1 xref: UniProtKB:Q6IF71 xref: UniProtKB:Q8NGD9 xref: UniProtKB:Q8NGT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019235 ! OR9A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057756 name: O2A12_HUMAN def: "Olfactory receptor 2A12" [UniProtKB:Q8NGT7] synonym: "Olfactory receptor OR7-10" EXACT [UniProtKB:Q8NGT7] xref: EMBL:BAC05917.1 xref: EMBL:DAA04817.1 xref: UniProtKB:Q6IF43 xref: UniProtKB:Q8NGT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018954 ! OR2A12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057757 name: OR2A1_HUMAN def: "Olfactory receptor 2A1/2A42" [UniProtKB:Q8NGT9] synonym: "Olfactory receptor OR7-16" EXACT [UniProtKB:Q8NGT9] synonym: "Olfactory receptor OR7-19" EXACT [UniProtKB:Q8NGT9] xref: EMBL:AAK95082.1 xref: EMBL:BAC05915.1 xref: EMBL:DAA04615.1 xref: EMBL:DAA04816.1 xref: UniProtKB:Q6IF44 xref: UniProtKB:Q8NGT9 xref: UniProtKB:Q96R46 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022478 ! OR2A1_human relationship: encoded_by CCO:G0022479 ! OR2A42_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057758 name: Q8NGU0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGU0] xref: EMBL:BAC05914.1 xref: UniProtKB:Q8NGU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057759 name: OR9A1_HUMAN def: "Putative olfactory receptor 9A1" [UniProtKB:Q8NGU1] synonym: "HSHTPRX06" EXACT [UniProtKB:Q8NGU1] xref: EMBL:BAC05913.1 xref: UniProtKB:Q8NGU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022482 ! OR9A1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057760 name: OR9A4_HUMAN def: "Olfactory receptor 9A4" [UniProtKB:Q8NGU2] xref: EMBL:BAC05912.1 xref: UniProtKB:Q8NGU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019236 ! OR9A4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057761 name: Q8NGU3_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGU3] xref: EMBL:BAC05910.1 xref: UniProtKB:Q8NGU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057762 name: OR2I1_HUMAN def: "Putative olfactory receptor 2I1" [UniProtKB:Q8NGU4] xref: EMBL:BAC05909.1 xref: UniProtKB:Q8NGU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019099 ! OR2I1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057763 name: Q8NGU6_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGU6] xref: EMBL:BAC05906.1 xref: UniProtKB:Q8NGU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021237 ! OR2J4P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057764 name: Q8NGU7_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGU7] xref: EMBL:BAC05905.1 xref: UniProtKB:Q8NGU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057765 name: GP150_HUMAN def: "Probable G-protein coupled receptor 150" [UniProtKB:Q8NGU9] xref: EMBL:BAC05903.1 xref: UniProtKB:Q8NGU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017974 ! GPR150_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057766 name: OR2Y1_HUMAN def: "Olfactory receptor 2Y1" [UniProtKB:Q8NGV0] synonym: "Olfactory receptor OR5-2" EXACT [UniProtKB:Q8NGV0] xref: EMBL:AAK95114.1 xref: EMBL:BAC05901.1 xref: EMBL:DAA04749.1 xref: UniProtKB:Q6IFB1 xref: UniProtKB:Q8NGV0 xref: UniProtKB:Q96R16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019126 ! OR2Y1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057767 name: Q8NGV8_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGV8] xref: EMBL:BAC05891.1 xref: UniProtKB:Q8NGV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057768 name: CSRL1_HUMAN def: "Putative calcium-sensing receptor-like 1" [UniProtKB:Q8NGV9] synonym: "Vomeronasal type-2 receptor-like" EXACT [UniProtKB:Q8NGV9] xref: EMBL:BAC05890.1 xref: UniProtKB:Q8NGV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017483 ! VN2R1P_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057769 name: OR6B3_HUMAN def: "Olfactory receptor 6B3" [UniProtKB:Q8NGW1] synonym: "Olfactory receptor OR2-2" EXACT [UniProtKB:Q8NGW1] xref: EMBL:BAC05888.1 xref: EMBL:DAA04687.1 xref: UniProtKB:Q6IFH3 xref: UniProtKB:Q8NGW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019197 ! OR6B3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057770 name: Q8NGW2_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGW2] xref: EMBL:BAC05887.1 xref: UniProtKB:Q8NGW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021238 ! DRD5P1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057771 name: Q8NGW3_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGW3] xref: EMBL:BAC05885.1 xref: UniProtKB:Q8NGW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057772 name: O11L1_HUMAN def: "Olfactory receptor 11L1" [UniProtKB:Q8NGX0] xref: EMBL:BAC05872.1 xref: UniProtKB:Q8NGX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018937 ! OR11L1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057773 name: O2T34_HUMAN def: "Olfactory receptor 2T34" [UniProtKB:Q8NGX1] synonym: "Olfactory receptor OR1-63" EXACT [UniProtKB:Q8NGX1] xref: EMBL:AAK95097.1 xref: EMBL:BAC05871.1 xref: EMBL:DAA04875.1 xref: UniProtKB:Q6IEY5 xref: UniProtKB:Q8NGX1 xref: UniProtKB:Q96R31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018970 ! OR2T34_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057774 name: O2T35_HUMAN def: "Olfactory receptor 2T35" [UniProtKB:Q8NGX2] synonym: "Olfactory receptor OR1-66" EXACT [UniProtKB:Q8NGX2] xref: EMBL:BAC05870.1 xref: EMBL:DAA04873.1 xref: UniProtKB:Q6IEY7 xref: UniProtKB:Q8NGX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018971 ! OR2T35_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057775 name: O10T2_HUMAN def: "Olfactory receptor 10T2" [UniProtKB:Q8NGX3] synonym: "Olfactory receptor OR1-3" EXACT [UniProtKB:Q8NGX3] xref: EMBL:BAC05869.1 xref: EMBL:CAI10867.1 xref: EMBL:DAA04762.1 xref: UniProtKB:Q6IF98 xref: UniProtKB:Q8NGX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018927 ! OR10T2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057776 name: Q8NGX4_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGX4] xref: EMBL:BAC05868.1 xref: UniProtKB:Q8NGX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018925 ! OR10K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057777 name: O10K1_HUMAN def: "Olfactory receptor 10K1" [UniProtKB:Q8NGX5] xref: EMBL:BAC05867.1 xref: UniProtKB:Q8NGX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018924 ! OR10K1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057778 name: Q8NGX7_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NGX7] xref: EMBL:BAC05865.1 xref: UniProtKB:Q8NGX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021239 ! OR10R3P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057779 name: OR6Y1_HUMAN def: "Olfactory receptor 6Y1" [UniProtKB:Q8NGX8] synonym: "Olfactory receptor OR1-11" EXACT [UniProtKB:Q8NGX8] xref: EMBL:BAC05864.1 xref: EMBL:CAH70563.1 xref: EMBL:DAA04590.1 xref: UniProtKB:Q6IFS0 xref: UniProtKB:Q8NGX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019212 ! OR6Y1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057780 name: OR6P1_HUMAN def: "Olfactory receptor 6P1" [UniProtKB:Q8NGX9] synonym: "Olfactory receptor OR1-12" EXACT [UniProtKB:Q8NGX9] xref: EMBL:BAC05863.1 xref: EMBL:CAH72416.1 xref: EMBL:DAA04591.1 xref: UniProtKB:Q6IFR9 xref: UniProtKB:Q8NGX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019208 ! OR6P1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057781 name: O10X1_HUMAN def: "Olfactory receptor 10X1" [UniProtKB:Q8NGY0] synonym: "Olfactory receptor OR1-14" EXACT [UniProtKB:Q8NGY0] xref: EMBL:BAC05862.1 xref: EMBL:CAH72417.1 xref: EMBL:DAA04592.1 xref: UniProtKB:Q6IFR8 xref: UniProtKB:Q8NGY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018930 ! OR10X1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057782 name: O10Z1_HUMAN def: "Olfactory receptor 10Z1" [UniProtKB:Q8NGY1] xref: EMBL:BAC05861.1 xref: EMBL:CAH73935.1 xref: UniProtKB:Q5VYL0 xref: UniProtKB:Q8NGY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018931 ! OR10Z1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057783 name: OR6K2_HUMAN def: "Olfactory receptor 6K2" [UniProtKB:Q8NGY2] xref: EMBL:BAC05860.1 xref: UniProtKB:Q8NGY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019205 ! OR6K2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057784 name: Q8NGY4_HUMAN def: "Seven transmembrane helix receptor (HCG39951)" [UniProtKB:Q8NGY4] xref: EMBL:BAC05858.1 xref: EMBL:EAW52813.1 xref: UniProtKB:Q8NGY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021240 ! hCG_39951_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057785 name: OR6N1_HUMAN def: "Olfactory receptor 6N1" [UniProtKB:Q8NGY5] xref: EMBL:AAK95093.1 xref: EMBL:BAC05857.1 xref: EMBL:CAH73792.1 xref: UniProtKB:Q5VUU8 xref: UniProtKB:Q8NGY5 xref: UniProtKB:Q96R35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019206 ! OR6N1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057786 name: OR6N2_HUMAN def: "Olfactory receptor 6N2" [UniProtKB:Q8NGY6] xref: EMBL:BAC05856.1 xref: UniProtKB:Q8NGY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019207 ! OR6N2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057787 name: O10J6_HUMAN def: "Putative olfactory receptor 10J6" [UniProtKB:Q8NGY7] xref: EMBL:AAK95073.1 xref: EMBL:BAC05855.1 xref: UniProtKB:Q8NGY7 xref: UniProtKB:Q96R55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018923 ! OR10J6P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057788 name: OR2L8_HUMAN def: "Olfactory receptor 2L8" [UniProtKB:Q8NGY9] synonym: "Olfactory receptor OR1-46" EXACT [UniProtKB:Q8NGY9] xref: EMBL:BAC05853.1 xref: EMBL:DAA04857.1 xref: UniProtKB:Q6IF03 xref: UniProtKB:Q8NGY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019107 ! OR2L8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057789 name: O2AJ1_HUMAN def: "Olfactory receptor 2AJ1" [UniProtKB:Q8NGZ0] xref: EMBL:BAC05852.1 xref: UniProtKB:Q8NGZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018960 ! OR2AJ1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057790 name: O14K1_HUMAN def: "Olfactory receptor 14K1" [UniProtKB:Q8NGZ2] synonym: "Olfactory receptor 5AY1" EXACT [UniProtKB:Q8NGZ2] synonym: "Olfactory receptor OR1-39" EXACT [UniProtKB:Q8NGZ2] xref: EMBL:AAK95075.1 xref: EMBL:BAC05850.1 xref: EMBL:DAA04775.1 xref: EMBL:EAW77201.1 xref: UniProtKB:A8MPV5 xref: UniProtKB:Q6IF85 xref: UniProtKB:Q8NGZ2 xref: UniProtKB:Q96R53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018953 ! OR14K1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057791 name: O13G1_HUMAN def: "Olfactory receptor 13G1" [UniProtKB:Q8NGZ3] xref: EMBL:BAC05849.1 xref: EMBL:CAI16305.1 xref: UniProtKB:Q5T2T2 xref: UniProtKB:Q8NGZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018946 ! OR13G1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057792 name: OR2G3_HUMAN def: "Olfactory receptor 2G3" [UniProtKB:Q8NGZ4] synonym: "Olfactory receptor OR1-33" EXACT [UniProtKB:Q8NGZ4] xref: EMBL:BAC05848.1 xref: EMBL:CAI17151.1 xref: EMBL:DAA04815.1 xref: UniProtKB:Q5JQT1 xref: UniProtKB:Q6IF45 xref: UniProtKB:Q8NGZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019095 ! OR2G3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057793 name: OR2G2_HUMAN def: "Olfactory receptor 2G2" [UniProtKB:Q8NGZ5] synonym: "Olfactory receptor OR1-32" EXACT [UniProtKB:Q8NGZ5] xref: EMBL:BAC05847.1 xref: EMBL:CAI17150.1 xref: EMBL:DAA04870.1 xref: UniProtKB:Q5JQT2 xref: UniProtKB:Q6IEZ0 xref: UniProtKB:Q8NGZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019094 ! OR2G2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057794 name: OR6F1_HUMAN def: "Olfactory receptor 6F1" [UniProtKB:Q8NGZ6] synonym: "Olfactory receptor OR1-38" EXACT [UniProtKB:Q8NGZ6] xref: EMBL:AAK95089.1 xref: EMBL:BAC05846.1 xref: EMBL:DAA04858.1 xref: UniProtKB:Q6IF02 xref: UniProtKB:Q8NGZ6 xref: UniProtKB:Q96R39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019203 ! OR6F1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057795 name: O2T10_HUMAN def: "Olfactory receptor 2T10" [UniProtKB:Q8NGZ9] synonym: "Olfactory receptor OR1-64" EXACT [UniProtKB:Q8NGZ9] xref: EMBL:BAC05843.1 xref: EMBL:DAA04876.1 xref: UniProtKB:Q8NGZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018964 ! OR2T10_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057796 name: OR2T4_HUMAN def: "Olfactory receptor 2T4" [UniProtKB:Q8NH00] synonym: "Olfactory receptor OR1-60" EXACT [UniProtKB:Q8NH00] xref: EMBL:BAC05842.1 xref: EMBL:DAA04862.1 xref: UniProtKB:Q6IEZ8 xref: UniProtKB:Q8NH00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019118 ! OR2T4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057797 name: O2T11_HUMAN def: "Olfactory receptor 2T11" [UniProtKB:Q8NH01] synonym: "Olfactory receptor OR1-65" EXACT [UniProtKB:Q8NH01] xref: EMBL:BAC05841.1 xref: EMBL:DAA04874.1 xref: UniProtKB:Q6IEY6 xref: UniProtKB:Q8NH01 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018965 ! OR2T11_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057798 name: O2T29_HUMAN def: "Olfactory receptor 2T29" [UniProtKB:Q8NH02] xref: EMBL:BAC05840.1 xref: UniProtKB:Q8NH02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018968 ! OR2T29_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057799 name: OR2T3_HUMAN def: "Olfactory receptor 2T3" [UniProtKB:Q8NH03] xref: EMBL:BAC05839.1 xref: UniProtKB:Q8NH03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019117 ! OR2T3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057800 name: O2T27_HUMAN def: "Olfactory receptor 2T27" [UniProtKB:Q8NH04] synonym: "Olfactory receptor OR1-67" EXACT [UniProtKB:Q8NH04] xref: EMBL:BAC05838.1 xref: EMBL:DAA04872.1 xref: UniProtKB:Q8NH04 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018967 ! OR2T27_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057801 name: OR4Q3_HUMAN def: "Olfactory receptor 4Q3" [UniProtKB:Q8NH05] synonym: "Olfactory receptor OR14-3" EXACT [UniProtKB:Q8NH05] xref: EMBL:BAC05836.1 xref: EMBL:DAA04886.1 xref: UniProtKB:Q6IEX4 xref: UniProtKB:Q8NH05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019172 ! OR4Q3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057802 name: OR1P1_HUMAN def: "Olfactory receptor 1P1" [UniProtKB:Q8NH06] synonym: "Olfactory receptor 17-208" EXACT [UniProtKB:Q8NH06] synonym: "Olfactory receptor OR17-9" EXACT [UniProtKB:Q8NH06] synonym: "OR17-208" EXACT [UniProtKB:Q8NH06] xref: EMBL:BAC05835.1 xref: UniProtKB:Q8NH06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019078 ! OR1P1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057803 name: O11H2_HUMAN def: "Olfactory receptor 11H2" [UniProtKB:Q8NH07] synonym: "Olfactory receptor OR14-1" EXACT [UniProtKB:Q8NH07] xref: EMBL:BAC05834.1 xref: EMBL:DAA04887.1 xref: UniProtKB:Q8NH07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018933 ! OR11H2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057804 name: O10AC_HUMAN def: "Putative olfactory receptor 10AC1" [UniProtKB:Q8NH08] synonym: "Olfactory receptor OR7-5" EXACT [UniProtKB:Q8NH08] xref: EMBL:BAC05833.1 xref: UniProtKB:Q8NH08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022467 ! OR10AC1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057805 name: OR8S1_HUMAN def: "Olfactory receptor 8S1" [UniProtKB:Q8NH09] xref: EMBL:BAC05832.1 xref: UniProtKB:Q8NH09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019234 ! OR8S1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057806 name: Q8NH11_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH11] xref: EMBL:BAC05830.1 xref: UniProtKB:Q8NH11 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057807 name: Q8NH14_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH14] xref: EMBL:BAC05827.1 xref: UniProtKB:Q8NH14 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057808 name: OR2L2_HUMAN def: "Olfactory receptor 2L2" [UniProtKB:Q8NH16] synonym: "HTPCRH07" EXACT [UniProtKB:Q8NH16] xref: EMBL:AAI04793.1 xref: EMBL:AAI04795.1 xref: EMBL:BAC05825.1 xref: UniProtKB:Q2M3T5 xref: UniProtKB:Q8NH16 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019104 ! OR2L2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057809 name: Q8NH17_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH17] xref: EMBL:BAC05824.1 xref: UniProtKB:Q8NH17 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057810 name: O10AG_HUMAN def: "Olfactory receptor 10AG1" [UniProtKB:Q8NH19] synonym: "Olfactory receptor OR11-160" EXACT [UniProtKB:Q8NH19] xref: EMBL:BAC05822.1 xref: EMBL:DAA04917.1 xref: UniProtKB:Q6IEU3 xref: UniProtKB:Q8NH19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018904 ! OR10AG1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057811 name: OR4F5_HUMAN def: "Olfactory receptor 4F5" [UniProtKB:Q8NH21] xref: EMBL:BAC05820.1 xref: EMBL:CAH72838.1 xref: UniProtKB:Q5VT22 xref: UniProtKB:Q8NH21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019156 ! OR4F5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057812 name: Q8NH22_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH22] xref: EMBL:BAC05819.1 xref: UniProtKB:Q8NH22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021241 ! DRD5P2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057813 name: Q8NH23_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH23] xref: EMBL:BAC05818.1 xref: UniProtKB:Q8NH23 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057814 name: Q8NH24_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH24] xref: EMBL:BAC05817.1 xref: UniProtKB:Q8NH24 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057815 name: Q8NH27_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH27] xref: EMBL:BAC05814.1 xref: UniProtKB:Q8NH27 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001319 ! muscarinic acetylcholine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057816 name: Q8NH29_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH29] xref: EMBL:BAC05812.1 xref: UniProtKB:Q8NH29 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057817 name: Q8NH32_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH32] xref: EMBL:BAC05809.1 xref: UniProtKB:Q8NH32 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057818 name: Q8NH33_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH33] xref: EMBL:BAC05808.1 xref: UniProtKB:Q8NH33 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057819 name: Q8NH36_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH36] xref: EMBL:BAC05805.1 xref: UniProtKB:Q8NH36 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057820 name: OR4C3_HUMAN def: "Olfactory receptor 4C3" [UniProtKB:Q8NH37] synonym: "Olfactory receptor OR11-98" EXACT [UniProtKB:Q8NH37] xref: EMBL:BAC05803.1 xref: EMBL:DAA04747.1 xref: UniProtKB:Q6IFB3 xref: UniProtKB:Q8NH37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019135 ! OR4C3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057821 name: Q8NH38_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH38] xref: EMBL:BAC05801.1 xref: UniProtKB:Q8NH38 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057822 name: OR4KD_HUMAN def: "Olfactory receptor 4K13" [UniProtKB:Q8NH42] synonym: "Olfactory receptor OR14-27" EXACT [UniProtKB:Q8NH42] xref: EMBL:BAC05797.1 xref: EMBL:DAA04847.1 xref: UniProtKB:Q6IF13 xref: UniProtKB:Q8NH42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019162 ! OR4K13_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057823 name: OR4L1_HUMAN def: "Olfactory receptor 4L1" [UniProtKB:Q8NH43] synonym: "Olfactory receptor OR14-28" EXACT [UniProtKB:Q8NH43] xref: EMBL:BAC05796.1 xref: EMBL:DAA04865.1 xref: UniProtKB:Q6IEZ5 xref: UniProtKB:Q8NH43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019164 ! OR4L1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057824 name: Q8NH44_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH44] xref: EMBL:BAC05795.1 xref: UniProtKB:Q8NH44 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057825 name: Q8NH47_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH47] xref: EMBL:BAC05792.1 xref: UniProtKB:Q8NH47 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057826 name: OR4X1_HUMAN def: "Olfactory receptor 4X1" [UniProtKB:Q8NH49] synonym: "Olfactory receptor OR11-104" EXACT [UniProtKB:Q8NH49] xref: EMBL:BAC05789.1 xref: EMBL:DAA04786.1 xref: UniProtKB:Q6IF74 xref: UniProtKB:Q8NH49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019175 ! OR4X1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057827 name: OR8K3_HUMAN def: "Olfactory receptor 8K3" [UniProtKB:Q8NH51] synonym: "Olfactory receptor OR11-181" EXACT [UniProtKB:Q8NH51] xref: EMBL:BAC05786.1 xref: EMBL:DAA04736.1 xref: UniProtKB:Q6IFC4 xref: UniProtKB:Q8NH51 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019233 ! OR8K3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057828 name: O52N1_HUMAN def: "Olfactory receptor 52N1" [UniProtKB:Q8NH53] xref: EMBL:BAC05784.1 xref: UniProtKB:Q8NH53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019018 ! OR52N1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057829 name: O56A3_HUMAN def: "Olfactory receptor 56A3" [UniProtKB:Q8NH54] xref: EMBL:BAC05783.1 xref: EMBL:DAA04703.1 xref: UniProtKB:A6NN77 xref: UniProtKB:Q6IFF7 xref: UniProtKB:Q8NH54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019025 ! OR56A3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0068952 ! O56A3_HUMAN-Phosphotyrosine172 [Term] id: CCO:B0057830 name: O52E5_HUMAN def: "Olfactory receptor 52E5" [UniProtKB:Q8NH55] xref: EMBL:BAC05782.1 xref: UniProtKB:Q8NH55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019010 ! OR52E5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057831 name: O52N5_HUMAN def: "Olfactory receptor 52N5" [UniProtKB:Q8NH56] synonym: "Olfactory receptor OR11-62" EXACT [UniProtKB:Q8NH56] xref: EMBL:AAI36982.1 xref: EMBL:BAC05781.1 xref: EMBL:DAA04698.1 xref: EMBL:EAW68762.1 xref: UniProtKB:Q6IFG2 xref: UniProtKB:Q8NH56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019021 ! OR52N5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057832 name: O52P1_HUMAN def: "Putative olfactory receptor 52P1" [UniProtKB:Q8NH57] xref: EMBL:BAC05780.1 xref: UniProtKB:Q8NH57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019022 ! OR52P1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057833 name: Q8NH58_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH58] xref: EMBL:BAC05779.1 xref: UniProtKB:Q8NH58 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057834 name: O51Q1_HUMAN def: "Olfactory receptor 51Q1" [UniProtKB:Q8NH59] xref: EMBL:BAC05778.1 xref: UniProtKB:Q8NH59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018999 ! OR51Q1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057835 name: O52J3_HUMAN def: "Olfactory receptor 52J3" [UniProtKB:Q8NH60] xref: EMBL:BAC05777.1 xref: UniProtKB:Q8NH60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019014 ! OR52J3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057836 name: Q8NH62_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH62] xref: EMBL:BAC05775.1 xref: UniProtKB:Q8NH62 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057837 name: O51H1_HUMAN def: "Putative olfactory receptor 51H1" [UniProtKB:Q8NH63] xref: EMBL:BAC05774.1 xref: UniProtKB:Q8NH63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018993 ! OR51H1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057838 name: O51A7_HUMAN def: "Olfactory receptor 51A7" [UniProtKB:Q8NH64] xref: EMBL:BAC05773.1 xref: UniProtKB:Q8NH64 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018982 ! OR51A7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057839 name: Q8NH66_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH66] xref: EMBL:BAC05771.1 xref: UniProtKB:Q8NH66 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057840 name: Q8NH68_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH68] xref: EMBL:BAC05769.1 xref: UniProtKB:Q8NH68 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057841 name: O4A16_HUMAN def: "Olfactory receptor 4A16" [UniProtKB:Q8NH70] synonym: "Olfactory receptor OR11-117" EXACT [UniProtKB:Q8NH70] xref: EMBL:BAC05767.1 xref: EMBL:DAA04647.1 xref: UniProtKB:Q6IFL3 xref: UniProtKB:Q8NH70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018973 ! OR4A16_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057842 name: Q8NH71_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH71] xref: EMBL:BAC05766.1 xref: UniProtKB:Q8NH71 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057843 name: OR4C6_HUMAN def: "Olfactory receptor 4C6" [UniProtKB:Q8NH72] synonym: "Olfactory receptor OR11-138" EXACT [UniProtKB:Q8NH72] xref: EMBL:BAC05765.1 xref: EMBL:DAA04728.1 xref: UniProtKB:Q6IFD2 xref: UniProtKB:Q8NH72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019137 ! OR4C6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057844 name: OR4S2_HUMAN def: "Olfactory receptor 4S2" [UniProtKB:Q8NH73] synonym: "Olfactory receptor OR11-137" EXACT [UniProtKB:Q8NH73] xref: EMBL:BAC05764.1 xref: EMBL:DAA04788.1 xref: UniProtKB:Q6IF72 xref: UniProtKB:Q8NH73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019174 ! OR4S2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0068982 ! OR4S2_HUMAN-Phosphoserine227 [Term] id: CCO:B0057845 name: O10A6_HUMAN def: "Olfactory receptor 10A6" [UniProtKB:Q8NH74] synonym: "Olfactory receptor OR11-96" EXACT [UniProtKB:Q8NH74] xref: EMBL:BAC05763.1 xref: EMBL:DAA04801.1 xref: UniProtKB:Q6IF59 xref: UniProtKB:Q8NH74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018901 ! OR10A6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057846 name: Q8NH75_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH75] xref: EMBL:BAC05762.1 xref: UniProtKB:Q8NH75 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057847 name: O56B4_HUMAN def: "Olfactory receptor 56B4" [UniProtKB:Q8NH76] xref: EMBL:BAC05761.1 xref: UniProtKB:Q8NH76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019028 ! OR56B4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057848 name: Q8NH77_HUMAN def: "Seven transmembrane helix receptor (HCG2044188)" [UniProtKB:Q8NH77] xref: EMBL:BAC05760.1 xref: EMBL:EAW68745.1 xref: UniProtKB:Q8NH77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021242 ! hCG_2044188_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057849 name: Q8NH78_HUMAN xref: UniProtKB:Q8NH78 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057850 name: OR6X1_HUMAN def: "Olfactory receptor 6X1" [UniProtKB:Q8NH79] synonym: "Olfactory receptor OR11-270" EXACT [UniProtKB:Q8NH79] xref: EMBL:BAC05758.1 xref: EMBL:DAA04760.1 xref: UniProtKB:Q6IFA0 xref: UniProtKB:Q8NH79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019211 ! OR6X1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057851 name: O10D3_HUMAN def: "Putative olfactory receptor 10D3" [UniProtKB:Q8NH80] synonym: "HTPCRX09" EXACT [UniProtKB:Q8NH80] synonym: "Olfactory receptor OR11-293" EXACT [UniProtKB:Q8NH80] xref: EMBL:BAC05757.1 xref: EMBL:DAA04823.1 xref: UniProtKB:Q8NH80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022468 ! OR10D3P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057852 name: O10G6_HUMAN def: "Olfactory receptor 10G6" [UniProtKB:Q8NH81] synonym: "Olfactory receptor OR11-280" EXACT [UniProtKB:Q8NH81] xref: EMBL:BAC05756.1 xref: EMBL:DAA04710.1 xref: UniProtKB:Q8NH81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018910 ! OR10G6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057853 name: Q8NH82_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH82] xref: EMBL:BAC05755.1 xref: UniProtKB:Q8NH82 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057854 name: OR4A5_HUMAN def: "Olfactory receptor 4A5" [UniProtKB:Q8NH83] synonym: "Olfactory receptor OR11-111" EXACT [UniProtKB:Q8NH83] xref: EMBL:BAC05754.1 xref: EMBL:DAA04776.1 xref: UniProtKB:Q6IF84 xref: UniProtKB:Q8NH83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019132 ! OR4A5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057855 name: Q8NH84_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH84] xref: EMBL:BAC05753.1 xref: UniProtKB:Q8NH84 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057856 name: Q8NH86_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH86] xref: EMBL:BAC05751.1 xref: UniProtKB:Q8NH86 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057857 name: OR9G1_HUMAN def: "Olfactory receptor 9G1" [UniProtKB:Q8NH87] synonym: "Olfactory receptor 9G5" EXACT [UniProtKB:Q8NH87] synonym: "Olfactory receptor OR11-114" EXACT [UniProtKB:Q8NH87] xref: EMBL:BAC05750.1 xref: EMBL:BAC05960.1 xref: EMBL:DAA04911.1 xref: UniProtKB:Q6IEU9 xref: UniProtKB:Q8NGQ0 xref: UniProtKB:Q8NH87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019237 ! OR9G1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057858 name: Q8NH88_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NH88] xref: EMBL:BAC05749.1 xref: UniProtKB:Q8NH88 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057859 name: OR1L3_HUMAN def: "Olfactory receptor 1L3" [UniProtKB:Q8NH93] synonym: "Olfactory receptor 9-D" EXACT [UniProtKB:Q8NH93] synonym: "Olfactory receptor OR9-28" EXACT [UniProtKB:Q8NH93] synonym: "OR9-D" EXACT [UniProtKB:Q8NH93] xref: EMBL:BAC05744.1 xref: EMBL:CAI16291.1 xref: EMBL:DAA04629.1 xref: UniProtKB:Q6IFN1 xref: UniProtKB:Q8NH93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019073 ! OR1L3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057860 name: YI035_HUMAN def: "Putative olfactory receptor ENSP00000348552" [UniProtKB:Q8NH95] xref: EMBL:BAC05742.1 xref: UniProtKB:Q8NH95 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057861 name: O2AE1_HUMAN def: "Olfactory receptor 2AE1" [UniProtKB:Q8NHA4] xref: EMBL:BAC05732.1 xref: UniProtKB:Q8NHA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018957 ! OR2AE1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057862 name: OR2W6_HUMAN def: "Putative olfactory receptor 2W6" [UniProtKB:Q8NHA6] synonym: "Olfactory receptor OR6-3" EXACT [UniProtKB:Q8NHA6] xref: EMBL:BAC05729.1 xref: EMBL:EAX03126.1 xref: UniProtKB:Q8NHA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022481 ! OR2W6P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057863 name: Q8NHA7_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHA7] xref: EMBL:BAC05728.1 xref: UniProtKB:Q8NHA7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057864 name: OR1FC_HUMAN def: "Olfactory receptor 1F12" [UniProtKB:Q8NHA8] synonym: "Hs6M1-35P" EXACT [UniProtKB:Q8NHA8] xref: EMBL:BAC05727.1 xref: UniProtKB:Q8NHA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019066 ! OR1F12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057865 name: Q8NHB0_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHB0] xref: EMBL:BAC05725.1 xref: UniProtKB:Q8NHB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057866 name: OR2V1_HUMAN def: "Olfactory receptor 2V1" [UniProtKB:Q8NHB1] xref: EMBL:BAC05724.1 xref: UniProtKB:Q8NHB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019122 ! OR2V1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057867 name: Q8NHB3_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHB3] xref: EMBL:BAC05722.1 xref: UniProtKB:Q8NHB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057868 name: Q8NHC2_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHC2] xref: EMBL:BAC05711.1 xref: UniProtKB:Q8NHC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057869 name: Q8NHC3_HUMAN def: "Seven transmembrane helix receptor" [UniProtKB:Q8NHC3] xref: EMBL:BAC05710.1 xref: UniProtKB:Q8NHC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057870 name: O10J5_HUMAN def: "Olfactory receptor 10J5" [UniProtKB:Q8NHC4] xref: EMBL:BAC05709.1 xref: UniProtKB:Q8NHC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018922 ! OR10J5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057871 name: O14AG_HUMAN def: "Olfactory receptor 14A16" [UniProtKB:Q8NHC5] synonym: "Olfactory receptor 5AT1" EXACT [UniProtKB:Q8NHC5] synonym: "Olfactory receptor OR1-45" EXACT [UniProtKB:Q8NHC5] xref: EMBL:BAC05708.1 xref: EMBL:DAA04764.1 xref: UniProtKB:Q6IF96 xref: UniProtKB:Q8NHC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018949 ! OR14A16_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057872 name: O14L1_HUMAN def: "Putative olfactory receptor 14L1" [UniProtKB:Q8NHC6] synonym: "Olfactory receptor 5AV1" EXACT [UniProtKB:Q8NHC6] xref: EMBL:BAC05707.1 xref: EMBL:CAI17152.1 xref: UniProtKB:Q5JQT0 xref: UniProtKB:Q8NHC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022470 ! OR14L1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057873 name: O14CZ_HUMAN def: "Olfactory receptor 14C36" [UniProtKB:Q8NHC7] synonym: "Olfactory receptor 5BF1" EXACT [UniProtKB:Q8NHC7] synonym: "Olfactory receptor OR1-59" EXACT [UniProtKB:Q8NHC7] xref: EMBL:BAC05706.1 xref: EMBL:CAH71667.1 xref: EMBL:DAA04864.1 xref: UniProtKB:Q6IEZ6 xref: UniProtKB:Q8NHC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018950 ! OR14C36_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057874 name: OR2T6_HUMAN def: "Olfactory receptor 2T6" [UniProtKB:Q8NHC8] synonym: "OST703" EXACT [UniProtKB:Q8NHC8] xref: EMBL:BAC05705.1 xref: UniProtKB:A6NE36 xref: UniProtKB:Q8NHC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019120 ! OR2T6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057875 name: LIRB4_HUMAN def: "Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor" [UniProtKB:Q8NHJ6] synonym: "CD85 antigen-like family member K" EXACT [UniProtKB:Q8NHJ6] synonym: "CD85k antigen" EXACT [UniProtKB:Q8NHJ6] synonym: "ILT-3" EXACT [UniProtKB:Q8NHJ6] synonym: "Immunoglobulin-like transcript 3" EXACT [UniProtKB:Q8NHJ6] synonym: "Leukocyte immunoglobulin-like receptor 5" EXACT [UniProtKB:Q8NHJ6] synonym: "LIR-5" EXACT [UniProtKB:Q8NHJ6] synonym: "Monocyte inhibitory receptor HM18" EXACT [UniProtKB:Q8NHJ6] xref: EMBL:AAB68665.1 xref: EMBL:AAB87666.1 xref: EMBL:AAG02024.1 xref: EMBL:AAH26309.1 xref: EMBL:AAL36992.1 xref: UniProtKB:O15468 xref: UniProtKB:O75021 xref: UniProtKB:Q8N1C7 xref: UniProtKB:Q8NHJ6 xref: UniProtKB:Q8NHL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018500 ! LILRB4_human relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067682 ! LIRB4_HUMAN-Phosphotyrosine360 [Term] id: CCO:B0057876 name: Q8NHU8_HUMAN def: "ZFP28 protein" [UniProtKB:Q8NHU8] xref: EMBL:AAH28416.1 xref: EMBL:AAH99903.1 xref: UniProtKB:Q8NHU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020587 ! ZFP28_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057877 name: RHXF1_HUMAN def: "Rhox homeobox family member 1" [UniProtKB:Q8NHV9] synonym: "Ovary-, testis- and epididymis-expressed gene protein" EXACT [UniProtKB:Q8NHV9] synonym: "Paired-like homeobox protein PEPP-1" EXACT [UniProtKB:Q8NHV9] xref: EMBL:AAC78617.1 xref: EMBL:AAH69324.1 xref: EMBL:AAH69529.1 xref: EMBL:AAI03858.1 xref: EMBL:AAI03859.1 xref: EMBL:AAM22794.1 xref: UniProtKB:O95030 xref: UniProtKB:Q3SYE0 xref: UniProtKB:Q8NHV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019740 ! RHOXF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057878 name: B4GN2_HUMAN def: "Beta-1,4 N-acetylgalactosaminyltransferase 2" [UniProtKB:Q8NHY0] synonym: "EC 2.4.1.-" EXACT [UniProtKB:Q8NHY0] synonym: "Sd(a) beta-1,4-GalNAc transferase" EXACT [UniProtKB:Q8NHY0] synonym: "UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase" EXACT [UniProtKB:Q8NHY0] xref: EMBL:AAI13676.1 xref: EMBL:AAI13678.1 xref: EMBL:AAM34756.1 xref: EMBL:CAD57148.1 xref: EMBL:CAD57149.1 xref: UniProtKB:Q14CP1 xref: UniProtKB:Q86Y40 xref: UniProtKB:Q8NHY0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017110 ! B4GALNT2_human relationship: has_function CCO:F0001852 ! acetylgalactosaminyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0003333 ! transferase activity, transferring hexosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000988 ! integral to Golgi membrane relationship: participates_in CCO:P0001238 ! negative regulation of cell-cell adhesion [Term] id: CCO:B0057879 name: ZFP28_HUMAN def: "Zinc finger protein 28 homolog" [UniProtKB:Q8NHY6] synonym: "Krueppel-like zinc finger factor X6" EXACT [UniProtKB:Q8NHY6] synonym: "Zfp-28" EXACT [UniProtKB:Q8NHY6] xref: EMBL:AAI27004.1 xref: EMBL:AAK28320.1 xref: EMBL:AAM28892.1 xref: EMBL:BAA92669.1 xref: UniProtKB:A0JNV6 xref: UniProtKB:Q8NHY6 xref: UniProtKB:Q9BY30 xref: UniProtKB:Q9P2B6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020587 ! ZFP28_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057880 name: Q8NHZ1_HUMAN def: "X-linked zinc finger protein isoform 5" [UniProtKB:Q8NHZ1] xref: EMBL:AAM33387.1 xref: UniProtKB:Q8NHZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020598 ! ZFX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057881 name: INADL_HUMAN def: "InaD-like protein" [UniProtKB:Q8NI35] synonym: "hINADL" EXACT [UniProtKB:Q8NI35] synonym: "Inadl protein" EXACT [UniProtKB:Q8NI35] synonym: "Pals1-associated tight junction protein" EXACT [UniProtKB:Q8NI35] synonym: "Protein associated to tight junctions" EXACT [UniProtKB:Q8NI35] xref: EMBL:AAH21135.1 xref: EMBL:AAM28433.1 xref: EMBL:BAB19683.1 xref: EMBL:CAA04666.1 xref: EMBL:CAA12112.1 xref: EMBL:CAA12113.1 xref: EMBL:CAH70416.1 xref: EMBL:CAH70418.1 xref: EMBL:CAH70420.1 xref: EMBL:CAI15923.1 xref: EMBL:CAI15925.1 xref: EMBL:CAI21733.1 xref: EMBL:CAI21734.1 xref: EMBL:CAI21737.1 xref: EMBL:CAI22258.1 xref: EMBL:CAI22260.1 xref: EMBL:CAI22262.1 xref: UniProtKB:O15249 xref: UniProtKB:O43742 xref: UniProtKB:O60833 xref: UniProtKB:Q5VUA5 xref: UniProtKB:Q5VUA6 xref: UniProtKB:Q5VUA7 xref: UniProtKB:Q5VUA8 xref: UniProtKB:Q5VUA9 xref: UniProtKB:Q5VUB0 xref: UniProtKB:Q8NI35 xref: UniProtKB:Q8WU78 xref: UniProtKB:Q9H3N9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018282 ! INADL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020537 ! ddx18-inadl physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0067093 ! INADL_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0067094 ! INADL_HUMAN-Phosphoserine522 relationship: transforms_into CCO:B0067095 ! INADL_HUMAN-Phosphoserine645 relationship: transforms_into CCO:B0067096 ! INADL_HUMAN-Phosphothreonine1209 relationship: transforms_into CCO:B0067097 ! INADL_HUMAN-Phosphoserine1212 [Term] id: CCO:B0057882 name: Q8NI49_HUMAN def: "Histamine H3 receptor isoform 6" [UniProtKB:Q8NI49] xref: EMBL:AAM43829.1 xref: UniProtKB:Q8NI49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018160 ! HRH3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057883 name: Q8NI50_HUMAN def: "Histamine H3 receptor isoform 5" [UniProtKB:Q8NI50] xref: EMBL:AAM43828.1 xref: UniProtKB:Q8NI50 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018160 ! HRH3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057884 name: ANGL6_HUMAN def: "Angiopoietin-related protein 6 precursor" [UniProtKB:Q8NI99] synonym: "Angiopoietin-like 6" EXACT [UniProtKB:Q8NI99] synonym: "Angiopoietin-related growth factor" EXACT [UniProtKB:Q8NI99] synonym: "Angiopoietin-related protein 5" EXACT [UniProtKB:Q8NI99] xref: EMBL:AAK06404.1 xref: EMBL:AAQ88643.1 xref: EMBL:BAB91248.1 xref: UniProtKB:Q8NI99 xref: UniProtKB:Q9BZZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016970 ! ANGPTL6_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000985 ! secretory granule relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057885 name: ZN563_HUMAN def: "Zinc finger protein 563" [UniProtKB:Q8TA94] xref: EMBL:AAH22523.1 xref: EMBL:BAC03810.1 xref: UniProtKB:Q8NAT7 xref: UniProtKB:Q8TA94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020822 ! ZNF563_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057886 name: PP14C_HUMAN def: "Protein phosphatase 1 regulatory subunit 14C" [UniProtKB:Q8TAE6] synonym: "Kinase-enhanced PP1 inhibitor" EXACT [UniProtKB:Q8TAE6] synonym: "PKC-potentiated PP1 inhibitory protein" EXACT [UniProtKB:Q8TAE6] synonym: "Serologically defined breast cancer antigen NY-BR-81" EXACT [UniProtKB:Q8TAE6] xref: EMBL:AAG48264.1 xref: EMBL:AAH15773.1 xref: EMBL:AAL83506.1 xref: EMBL:AAL83507.1 xref: EMBL:CAH74129.1 xref: EMBL:CAI19346.1 xref: UniProtKB:Q5VY83 xref: UniProtKB:Q8TAE6 xref: UniProtKB:Q96BB1 xref: UniProtKB:Q9H277 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019473 ! PPP1R14C_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001221 ! type 1 serine/threonine specific protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: transforms_into CCO:B0069446 ! PP14C_HUMAN-Phosphothreonine73 [Term] id: CCO:B0057887 name: ZN461_HUMAN def: "Zinc finger protein 461" [UniProtKB:Q8TAF7] synonym: "GIOT-1" EXACT [UniProtKB:Q8TAF7] synonym: "Gonadotropin-inducible transcription repressor 1" EXACT [UniProtKB:Q8TAF7] xref: EMBL:AAH28631.1 xref: EMBL:AAR00226.1 xref: EMBL:BAA86987.1 xref: UniProtKB:Q6VSF7 xref: UniProtKB:Q8TAF7 xref: UniProtKB:Q9ULZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020760 ! ZNF461_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057888 name: OLIG1_HUMAN def: "Oligodendrocyte transcription factor 1" [UniProtKB:Q8TAK6] synonym: "Oligo1" EXACT [UniProtKB:Q8TAK6] xref: EMBL:AAH26989.1 xref: EMBL:AAH33290.1 xref: EMBL:CAD39110.1 xref: EMBL:DAA01058.1 xref: UniProtKB:Q7RTS0 xref: UniProtKB:Q8TAK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019042 ! OLIG1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057889 name: Q8TAL0_HUMAN def: "PPARGC1B protein" [UniProtKB:Q8TAL0] xref: EMBL:AAH26956.1 xref: UniProtKB:Q8TAL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019508 ! PPARGC1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0007991 ! AF-2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0057890 name: LMO3_HUMAN def: "LIM domain only protein 3" [UniProtKB:Q8TAP4] synonym: "Neuronal-specific transcription factor DAT1" EXACT [UniProtKB:Q8TAP4] synonym: "Rhombotin-3" EXACT [UniProtKB:Q8TAP4] xref: EMBL:AAH26311.1 xref: EMBL:BAC04582.1 xref: UniProtKB:Q8N974 xref: UniProtKB:Q8TAP4 xref: UniProtKB:Q9UDD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018509 ! LMO3_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015188 ! als2cr8-lmo3 physical interaction relationship: participates_in CCO:I0015239 ! lmo3-q96br9 physical interaction relationship: participates_in CCO:I0015255 ! lmo3-znf297b physical interaction relationship: participates_in CCO:I0015258 ! kiaa0470l-lmo3 physical interaction relationship: participates_in CCO:I0015304 ! gabpb2-lmo3 physical interaction relationship: participates_in CCO:I0015414 ! lmo3-mgc2749 physical interaction relationship: participates_in CCO:I0015419 ! ldb1-lmo3 physical interaction relationship: participates_in CCO:I0015510 ! lmo3-rfxdc1 physical interaction relationship: participates_in CCO:I0015592 ! lmo3-mdfi physical interaction relationship: participates_in CCO:I0015730 ! hnrpm-lmo3 physical interaction relationship: participates_in CCO:I0015760 ! hnrpc-lmo3 physical interaction relationship: participates_in CCO:I0015804 ! lmo3-mbip physical interaction relationship: participates_in CCO:I0017583 ! lmo3-rora physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057891 name: ZN420_HUMAN def: "Zinc finger protein 420" [UniProtKB:Q8TAQ5] xref: EMBL:AAH26210.1 xref: EMBL:BAG38083.1 xref: UniProtKB:B2RDY6 xref: UniProtKB:Q8TAQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020742 ! ZNF420_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072121 ! ZN420_HUMAN-Phosphoserine488 [Term] id: CCO:B0057892 name: NKX23_HUMAN def: "Homeobox protein Nkx-2.3" [UniProtKB:Q8TAU0] synonym: "Homeobox protein NK-2 homolog C" EXACT [UniProtKB:Q8TAU0] xref: EMBL:AAF44651.1 xref: EMBL:AAH25788.1 xref: EMBL:CAI16899.1 xref: UniProtKB:Q8TAU0 xref: UniProtKB:Q9NYS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018796 ! NKX2-3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057893 name: ZN417_HUMAN def: "Zinc finger protein 417" [UniProtKB:Q8TAU3] xref: EMBL:AAH25783.1 xref: UniProtKB:Q8TAU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020740 ! ZNF417_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014976 ! znf297b-znf417 physical interaction relationship: participates_in CCO:I0015310 ! begain-znf417 physical interaction relationship: participates_in CCO:I0015393 ! krtap4_12-znf417 physical interaction relationship: participates_in CCO:I0015469 ! cep72-znf417 physical interaction relationship: participates_in CCO:I0015548 ! mdfi-znf417 physical interaction relationship: participates_in CCO:I0015584 ! trim37-znf417 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057894 name: STML3_HUMAN def: "Stomatin-like protein 3" [UniProtKB:Q8TAV4] xref: EMBL:AAH25760.1 xref: EMBL:CAI40973.1 xref: UniProtKB:Q5JS35 xref: UniProtKB:Q8TAV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020071 ! STOML3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057895 name: ZN671_HUMAN def: "Zinc finger protein 671" [UniProtKB:Q8TAW3] xref: EMBL:AAH25728.1 xref: EMBL:BAB15677.1 xref: UniProtKB:Q8TAW3 xref: UniProtKB:Q9H5E9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020887 ! ZNF671_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057896 name: RIN3_HUMAN def: "Ras and Rab interactor 3" [UniProtKB:Q8TB24] synonym: "Ras interaction/interference protein 3" EXACT [UniProtKB:Q8TB24] xref: EMBL:AAH25248.2 xref: EMBL:BAB13888.1 xref: EMBL:BAB15357.1 xref: EMBL:BAB84316.1 xref: EMBL:BAB85002.1 xref: EMBL:BAC03432.1 xref: EMBL:BAC16513.1 xref: UniProtKB:Q76LB3 xref: UniProtKB:Q8NF30 xref: UniProtKB:Q8TB24 xref: UniProtKB:Q8TEE8 xref: UniProtKB:Q8WYP4 xref: UniProtKB:Q9H6A5 xref: UniProtKB:Q9HAG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019744 ! RIN3_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003512 ! Ras GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057897 name: Q8TB56_HUMAN def: "Microtubule-associated protein" [UniProtKB:Q8TB56] xref: EMBL:AAH24302.1 xref: UniProtKB:Q8TB56 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization [Term] id: CCO:B0057898 name: S35B2_HUMAN def: "Adenosine 3'-phospho 5'-phosphosulfate transporter 1" [UniProtKB:Q8TB61] synonym: "PAPS transporter 1" EXACT [UniProtKB:Q8TB61] synonym: "Putative MAPK-activating protein PM15" EXACT [UniProtKB:Q8TB61] synonym: "Putative NF-kappa-B-activating protein 48" EXACT [UniProtKB:Q8TB61] synonym: "Solute carrier family 35 member B2" EXACT [UniProtKB:Q8TB61] xref: EMBL:AAH16839.1 xref: EMBL:AAH24288.1 xref: EMBL:AAS79661.1 xref: EMBL:BAC11631.1 xref: EMBL:BAC77374.1 xref: EMBL:BAC77392.1 xref: EMBL:BAC79117.1 xref: EMBL:BAD96748.1 xref: EMBL:CAI20100.2 xref: EMBL:CAI20101.2 xref: UniProtKB:Q2VY06 xref: UniProtKB:Q53GA3 xref: UniProtKB:Q5T9W1 xref: UniProtKB:Q5T9W2 xref: UniProtKB:Q7Z2G3 xref: UniProtKB:Q8NBK6 xref: UniProtKB:Q8TB61 xref: UniProtKB:Q96AR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019825 ! SLC35B2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0070283 ! S35B2_HUMAN-Phosphoserine427 [Term] id: CCO:B0057899 name: ZN519_HUMAN def: "Zinc finger protein 519" [UniProtKB:Q8TB69] xref: EMBL:AAH24227.1 xref: UniProtKB:Q8TB69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020794 ! ZNF519_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057900 name: Q8TB74_HUMAN def: "Similar to Cytochrome c, somatic" [UniProtKB:Q8TB74] xref: EMBL:AAH19340.1 xref: UniProtKB:Q8TB74 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021243 ! MGC12965_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057901 name: ZSC18_HUMAN def: "Zinc finger and SCAN domain-containing protein 18" [UniProtKB:Q8TBC5] synonym: "Zinc finger protein 447" EXACT [UniProtKB:Q8TBC5] xref: EMBL:AAH06205.2 xref: EMBL:AAH22846.1 xref: EMBL:AAQ16303.1 xref: EMBL:BAB14332.1 xref: UniProtKB:Q8TBC5 xref: UniProtKB:Q9BRK7 xref: UniProtKB:Q9H9A0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021001 ! ZSCAN18_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057902 name: CNIH3_HUMAN def: "Protein cornichon homolog 3" [UniProtKB:Q8TBE1] xref: EMBL:AAH22780.1 xref: EMBL:BAC04760.1 xref: EMBL:CAH73437.1 xref: UniProtKB:Q8TBE1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017402 ! CNIH3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057903 name: Q8TBJ3_HUMAN def: "Zinc finger protein 223 (cDNA FLJ77594, highly similar to Homo sapiens zinc finger protein 223 (ZNF223), mRNA)" [UniProtKB:Q8TBJ3] xref: EMBL:AAH22466.1 xref: EMBL:BAF85016.1 xref: UniProtKB:Q8TBJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020663 ! ZNF223_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057904 name: FEZF2_HUMAN def: "Fez family zinc finger protein 2" [UniProtKB:Q8TBJ5] synonym: "Forebrain embryonic zinc finger-like protein 2" EXACT [UniProtKB:Q8TBJ5] synonym: "Zinc finger protein 312" EXACT [UniProtKB:Q8TBJ5] synonym: "Zinc finger protein Fez-like" EXACT [UniProtKB:Q8TBJ5] xref: EMBL:AAG50287.1 xref: EMBL:AAH22464.1 xref: EMBL:BAA91464.1 xref: UniProtKB:Q8TBJ5 xref: UniProtKB:Q9BZ91 xref: UniProtKB:Q9NWB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017780 ! FEZF2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057905 name: Q8TBM4_HUMAN def: "DGKE protein" [UniProtKB:Q8TBM4] xref: EMBL:AAH22297.1 xref: UniProtKB:Q8TBM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057906 name: TBC16_HUMAN def: "TBC1 domain family member 16" [UniProtKB:Q8TBP0] xref: EMBL:AAH28290.1 xref: UniProtKB:Q8TBP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020161 ! TBC1D16_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057907 name: Q8TBS2_HUMAN def: "ZNF496 protein" [UniProtKB:Q8TBS2] xref: EMBL:AAH25794.1 xref: UniProtKB:Q8TBS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020778 ! ZNF496_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057908 name: ZN502_HUMAN def: "Zinc finger protein 502" [UniProtKB:Q8TBZ5] xref: EMBL:AAH28377.1 xref: UniProtKB:Q8TBZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020783 ! ZNF502_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057909 name: ZN564_HUMAN def: "Zinc finger protein 564" [UniProtKB:Q8TBZ8] xref: EMBL:AAH28367.2 xref: EMBL:BAC03967.1 xref: UniProtKB:Q8TBZ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020823 ! ZNF564_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057910 name: TBC15_HUMAN def: "TBC1 domain family member 15" [UniProtKB:Q8TC07] xref: EMBL:AAH28352.1 xref: EMBL:BAB13971.1 xref: UniProtKB:Q8TC07 xref: UniProtKB:Q9HA83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020160 ! TBC1D15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071209 ! TBC15_HUMAN-Phosphoserine70 relationship: transforms_into CCO:B0071210 ! TBC15_HUMAN-Phosphotyrosine180 relationship: transforms_into CCO:B0071211 ! TBC15_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0071212 ! TBC15_HUMAN-Phosphotyrosine215 relationship: transforms_into CCO:B0071213 ! TBC15_HUMAN-Phosphoserine675 relationship: transforms_into CCO:B0071214 ! TBC15_HUMAN-Phosphothreonine689 [Term] id: CCO:B0057911 name: ZN596_HUMAN def: "Zinc finger protein 596" [UniProtKB:Q8TC21] xref: EMBL:AAD05197.1 xref: EMBL:AAH26190.2 xref: EMBL:BAC04166.1 xref: UniProtKB:O95015 xref: UniProtKB:Q8N9X0 xref: UniProtKB:Q8TC21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020846 ! ZNF596_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057912 name: Q8TC43_HUMAN def: "ZNF585A protein" [UniProtKB:Q8TC43] xref: EMBL:AAH26081.1 xref: UniProtKB:Q8TC43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020531 ! ZNF585A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057913 name: O51E1_HUMAN def: "Olfactory receptor 51E1" [UniProtKB:Q8TCB6] synonym: "D-GPCR" EXACT [UniProtKB:Q8TCB6] synonym: "G-protein coupled receptor 164" EXACT [UniProtKB:Q8TCB6] synonym: "Prostate overexpressed G protein-coupled receptor" EXACT [UniProtKB:Q8TCB6] synonym: "Prostate-specific G protein-coupled receptor 2" EXACT [UniProtKB:Q8TCB6] xref: EMBL:AAH22401.1 xref: EMBL:AAU07996.1 xref: EMBL:AAV54110.1 xref: EMBL:BAC06006.1 xref: EMBL:DAA04767.1 xref: UniProtKB:Q5S4P5 xref: UniProtKB:Q66X57 xref: UniProtKB:Q6IF93 xref: UniProtKB:Q8TCB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018988 ! OR51E1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057914 name: CR032_HUMAN def: "Uncharacterized protein C18orf32" [UniProtKB:Q8TCD1] synonym: "Putative NF-kappa-B-activating protein 200" EXACT [UniProtKB:Q8TCD1] xref: EMBL:AAH22357.1 xref: EMBL:AAH93004.1 xref: EMBL:BAC77365.1 xref: EMBL:BAF84571.1 xref: UniProtKB:Q8TCD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017445 ! C18orf32_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0057915 name: ZN507_HUMAN def: "Zinc finger protein 507" [UniProtKB:Q8TCN5] xref: EMBL:AAI10333.1 xref: EMBL:BAA83036.2 xref: EMBL:BAF85215.1 xref: EMBL:CAD28536.1 xref: EMBL:CAE45937.1 xref: UniProtKB:A8K911 xref: UniProtKB:Q2TBF1 xref: UniProtKB:Q6MZU0 xref: UniProtKB:Q8TCN5 xref: UniProtKB:Q9UPR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020786 ! ZNF507_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072138 ! ZN507_HUMAN-Phosphoserine195 [Term] id: CCO:B0057916 name: CERK1_HUMAN def: "Ceramide kinase" [UniProtKB:Q8TCT0] synonym: "Acylsphingosine kinase" EXACT [UniProtKB:Q8TCT0] synonym: "EC 2.7.1.138" EXACT [UniProtKB:Q8TCT0] synonym: "hCERK" EXACT [UniProtKB:Q8TCT0] synonym: "Lipid kinase 4" EXACT [UniProtKB:Q8TCT0] synonym: "LK4" EXACT [UniProtKB:Q8TCT0] xref: EMBL:AAI26941.1 xref: EMBL:BAB33316.1 xref: EMBL:BAC01154.1 xref: EMBL:CAD29884.1 xref: EMBL:CAG30290.1 xref: EMBL:CAI17953.1 xref: EMBL:CAI18819.1 xref: UniProtKB:A0JNT4 xref: UniProtKB:Q8TCT0 xref: UniProtKB:Q9BYB3 xref: UniProtKB:Q9UGE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017336 ! CERK_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000205 ! ceramide kinase activity relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000050 ! integral to membrane of membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity [Term] id: CCO:B0057917 name: PKR1_HUMAN def: "Prokineticin receptor 1" [UniProtKB:Q8TCW9] synonym: "G-protein coupled receptor 73" EXACT [UniProtKB:Q8TCW9] synonym: "G-protein coupled receptor ZAQ" EXACT [UniProtKB:Q8TCW9] synonym: "GPR73a" EXACT [UniProtKB:Q8TCW9] synonym: "PK-R1" EXACT [UniProtKB:Q8TCW9] xref: EMBL:AAI00961.1 xref: EMBL:AAM11892.1 xref: EMBL:AAM48127.1 xref: EMBL:AAY24114.1 xref: EMBL:BAC24021.1 xref: UniProtKB:Q53QT9 xref: UniProtKB:Q8NFJ7 xref: UniProtKB:Q8TCW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019425 ! PROKR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057918 name: RHPN1_HUMAN def: "Rhophilin-1" [UniProtKB:Q8TCX5] synonym: "GTP-Rho-binding protein 1" EXACT [UniProtKB:Q8TCX5] xref: EMBL:AAH25767.1 xref: EMBL:AAL89809.1 xref: EMBL:BAB67822.1 xref: UniProtKB:Q8TAV1 xref: UniProtKB:Q8TCX5 xref: UniProtKB:Q96PV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019738 ! RHPN1_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015246 ! rhpn1-trim37 physical interaction relationship: participates_in CCO:I0015601 ! krt15-rhpn1 physical interaction relationship: participates_in CCO:I0015694 ! efemp2-rhpn1 physical interaction relationship: participates_in CCO:I0015726 ! ndp52-rhpn1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057919 name: PKHD1_HUMAN def: "Fibrocystin precursor" [UniProtKB:Q8TCZ9] synonym: "Polycystic kidney and hepatic disease 1 protein" EXACT [UniProtKB:Q8TCZ9] synonym: "Polyductin" EXACT [UniProtKB:Q8TCZ9] synonym: "Tigmin" EXACT [UniProtKB:Q8TCZ9] xref: EMBL:AAL74290.1 xref: EMBL:AAM18186.1 xref: EMBL:AAM44232.1 xref: UniProtKB:Q8TCZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019411 ! PKHD1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000484 ! basal body relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001218 ! anchored to external side of plasma membrane relationship: participates_in CCO:P0003072 ! negative regulation of cell motility [Term] id: CCO:B0057920 name: ZN398_HUMAN def: "Zinc finger protein 398" [UniProtKB:Q8TD17] synonym: "Zinc finger DNA-binding protein p52/p71" EXACT [UniProtKB:Q8TD17] xref: EMBL:AAH43295.1 xref: EMBL:AAK92788.1 xref: EMBL:AAK92789.1 xref: EMBL:BAA92577.1 xref: UniProtKB:Q8TD17 xref: UniProtKB:Q8TD18 xref: UniProtKB:Q9P2K7 xref: UniProtKB:Q9UDV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020731 ! ZNF398_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057921 name: CHD6_HUMAN def: "Chromodomain-helicase-DNA-binding protein 6" [UniProtKB:Q8TD26] synonym: "ATP-dependent helicase CHD6" EXACT [UniProtKB:Q8TD26] synonym: "CHD-6" EXACT [UniProtKB:Q8TD26] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q8TD26] synonym: "Radiation-induced gene B protein" EXACT [UniProtKB:Q8TD26] xref: EMBL:AAH21907.1 xref: EMBL:AAK56405.1 xref: EMBL:AAN59903.1 xref: EMBL:BAA92573.2 xref: EMBL:BAB15325.1 xref: EMBL:CAI21743.1 xref: EMBL:CAI21744.1 xref: EMBL:CAI21745.1 xref: EMBL:CAI22254.1 xref: EMBL:CAI22255.1 xref: EMBL:CAI22256.1 xref: EMBL:CAI42977.1 xref: EMBL:CAI42981.1 xref: EMBL:CAI42983.1 xref: UniProtKB:Q5JYQ0 xref: UniProtKB:Q5TGZ9 xref: UniProtKB:Q5TH00 xref: UniProtKB:Q5TH01 xref: UniProtKB:Q8IZR2 xref: UniProtKB:Q8TD26 xref: UniProtKB:Q8WTY0 xref: UniProtKB:Q9H4H6 xref: UniProtKB:Q9H6D4 xref: UniProtKB:Q9NTT7 xref: UniProtKB:Q9P2L1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017351 ! CHD6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064324 ! CHD6_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0064325 ! CHD6_HUMAN-Phosphoserine1069 relationship: transforms_into CCO:B0064326 ! CHD6_HUMAN-Phosphoserine1073 relationship: transforms_into CCO:B0064327 ! CHD6_HUMAN-Phosphoserine2041 [Term] id: CCO:B0057922 name: KLF14_HUMAN def: "Krueppel-like factor 14" [UniProtKB:Q8TD94] synonym: "Basic transcription element-binding protein 5" EXACT [UniProtKB:Q8TD94] synonym: "BTE-binding protein 5" EXACT [UniProtKB:Q8TD94] synonym: "Transcription factor BTEB5" EXACT [UniProtKB:Q8TD94] xref: EMBL:AAM08349.1 xref: EMBL:ABF82392.1 xref: EMBL:ABF82393.1 xref: UniProtKB:Q19A42 xref: UniProtKB:Q19A43 xref: UniProtKB:Q8TD94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018412 ! KLF14_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067373 ! KLF14_HUMAN-Phosphothreonine237 [Term] id: CCO:B0057923 name: Q8TDA2_HUMAN def: "BCRe18/ABL1e3 fusion protein" [UniProtKB:Q8TDA2] xref: EMBL:AAL99544.1 xref: UniProtKB:Q8TDA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008391 ! BCR/ABL fusion_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057924 name: Q8TDA3_HUMAN xref: UniProtKB:Q8TDA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0057925 name: DDX54_HUMAN def: "ATP-dependent RNA helicase DDX54" [UniProtKB:Q8TDD1] synonym: "ATP-dependent RNA helicase DP97" EXACT [UniProtKB:Q8TDD1] synonym: "DEAD box protein 54" EXACT [UniProtKB:Q8TDD1] synonym: "DEAD box RNA helicase 97 kDa" EXACT [UniProtKB:Q8TDD1] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q8TDD1] xref: EMBL:AAH05848.2 xref: EMBL:AAL85336.1 xref: EMBL:AAN59978.1 xref: UniProtKB:Q86YT8 xref: UniProtKB:Q8TDD1 xref: UniProtKB:Q9BRZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017548 ! DDX54_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: transforms_into CCO:B0064712 ! DDX54_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0064713 ! DDX54_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0064714 ! DDX54_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0064715 ! DDX54_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0064716 ! DDX54_HUMAN-Phosphoserine644 relationship: transforms_into CCO:B0064717 ! DDX54_HUMAN-Phosphoserine782 relationship: transforms_into CCO:B0064718 ! DDX54_HUMAN-Phosphoserine788 [Term] id: CCO:B0057926 name: SP7_HUMAN def: "Transcription factor Sp7" [UniProtKB:Q8TDD2] synonym: "Zinc finger protein osterix" EXACT [UniProtKB:Q8TDD2] xref: EMBL:AAI01550.1 xref: EMBL:AAI13614.1 xref: EMBL:AAL84281.1 xref: EMBL:AAN85556.1 xref: EMBL:AAO33377.1 xref: UniProtKB:Q3MJ72 xref: UniProtKB:Q8TDD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020006 ! SP7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0057927 name: GRP4_HUMAN def: "RAS guanyl-releasing protein 4" [UniProtKB:Q8TDF6] xref: EMBL:AAI46670.1 xref: EMBL:AAI50203.1 xref: EMBL:AAK85701.1 xref: EMBL:AAK85702.1 xref: EMBL:AAK85703.1 xref: EMBL:AAL87858.1 xref: EMBL:BAC04992.1 xref: UniProtKB:A6H8M4 xref: UniProtKB:Q8N858 xref: UniProtKB:Q8TDF6 xref: UniProtKB:Q96QN5 xref: UniProtKB:Q96QN6 xref: UniProtKB:Q96QN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018078 ! RASGRP4_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057928 name: CHD5_HUMAN def: "Chromodomain-helicase-DNA-binding protein 5" [UniProtKB:Q8TDI0] synonym: "ATP-dependent helicase CHD5" EXACT [UniProtKB:Q8TDI0] synonym: "CHD-5" EXACT [UniProtKB:Q8TDI0] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q8TDI0] xref: EMBL:AAL98962.1 xref: EMBL:BAA32289.1 xref: EMBL:CAB55959.1 xref: EMBL:CAI19450.1 xref: EMBL:CAI19891.1 xref: UniProtKB:O75032 xref: UniProtKB:Q5TG89 xref: UniProtKB:Q7LGH2 xref: UniProtKB:Q8TDI0 xref: UniProtKB:Q9UFR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017350 ! CHD5_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057929 name: Q8TDP6_HUMAN def: "CC chemokine receptor 3" [UniProtKB:Q8TDP6] xref: EMBL:AAL85630.1 xref: UniProtKB:Q8TDP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017278 ! CCR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057930 name: Q8TDP8_HUMAN def: "CC chemokine receptor 3" [UniProtKB:Q8TDP8] xref: EMBL:AAL85628.1 xref: UniProtKB:Q8TDP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017278 ! CCR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057931 name: Q8TDS3_HUMAN def: "Delta 4 progesterone receptor" [UniProtKB:Q8TDS3] synonym: "Progesterone receptor, isoform CRA_c" EXACT [UniProtKB:Q8TDS3] xref: EMBL:BAB91074.1 xref: EMBL:EAW66999.1 xref: UniProtKB:Q8TDS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021244 ! PR_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057932 name: G109A_HUMAN def: "Nicotinic acid receptor 1" [UniProtKB:Q8TDS4] synonym: "G-protein coupled receptor 109A" EXACT [UniProtKB:Q8TDS4] synonym: "G-protein coupled receptor HM74A" EXACT [UniProtKB:Q8TDS4] xref: EMBL:AAH27965.1 xref: EMBL:AAH56419.1 xref: EMBL:AAN71621.1 xref: EMBL:ABS29270.1 xref: EMBL:BAB89345.1 xref: EMBL:BAC06094.1 xref: UniProtKB:A0PJL5 xref: UniProtKB:A7LGG3 xref: UniProtKB:Q8TDS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017855 ! GPR109A_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057933 name: OXER1_HUMAN def: "Oxoeicosanoid receptor 1" [UniProtKB:Q8TDS5] synonym: "5-oxo-ETE G-protein coupled receptor" EXACT [UniProtKB:Q8TDS5] synonym: "G-protein coupled receptor 170" EXACT [UniProtKB:Q8TDS5] synonym: "G-protein coupled receptor R527" EXACT [UniProtKB:Q8TDS5] synonym: "G-protein coupled receptor TG1019" EXACT [UniProtKB:Q8TDS5] xref: EMBL:AAH63549.1 xref: EMBL:AAO17739.1 xref: EMBL:AAY14700.1 xref: EMBL:BAB89343.1 xref: EMBL:BAC05878.1 xref: EMBL:BAC11806.2 xref: UniProtKB:Q86WP7 xref: UniProtKB:Q8NGW4 xref: UniProtKB:Q8TDS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019253 ! OXER1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0007980 ! 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding relationship: has_function CCO:F0007981 ! 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding relationship: has_function CCO:F0007982 ! 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001310 ! regulation of cAMP biosynthetic process [Term] id: CCO:B0057934 name: MRGRD_HUMAN def: "Mas-related G-protein coupled receptor member D" [UniProtKB:Q8TDS7] synonym: "Beta-alanine receptor" EXACT [UniProtKB:Q8TDS7] synonym: "G-protein coupled receptor TGR7" EXACT [UniProtKB:Q8TDS7] xref: EMBL:AAR05120.1 xref: EMBL:BAB89340.1 xref: EMBL:BAC06005.1 xref: EMBL:BAD20638.1 xref: UniProtKB:Q8NGK7 xref: UniProtKB:Q8TDS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018654 ! MRGPRD_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057935 name: GP152_HUMAN def: "Probable G-protein coupled receptor 152" [UniProtKB:Q8TDT2] synonym: "G-protein coupled receptor PGR5" EXACT [UniProtKB:Q8TDT2] xref: EMBL:AAI19780.1 xref: EMBL:AAI22870.1 xref: EMBL:AAO85112.1 xref: EMBL:AAS76893.1 xref: EMBL:BAB89333.1 xref: EMBL:BAC06071.1 xref: UniProtKB:Q0VD88 xref: UniProtKB:Q86SM0 xref: UniProtKB:Q8TDT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017976 ! GPR152_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057936 name: Q8TDT4_HUMAN def: "Putative G-protein coupled receptor" [UniProtKB:Q8TDT4] xref: EMBL:BAB89331.1 xref: UniProtKB:Q8TDT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021210 ! GPCR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0057937 name: Q8TDT9_HUMAN def: "Putative G-protein coupled receptor" [UniProtKB:Q8TDT9] xref: EMBL:BAB89325.1 xref: UniProtKB:Q8TDT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021210 ! GPCR_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0057938 name: VNRL4_HUMAN def: "Putative vomeronasal receptor-like protein 4" [UniProtKB:Q8TDU5] synonym: "hGPCR23" EXACT [UniProtKB:Q8TDU5] xref: EMBL:BAB89318.1 xref: UniProtKB:Q8TDU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020460 ! VNRL4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057939 name: GPBAR_HUMAN def: "G-protein coupled bile acid receptor 1" [UniProtKB:Q8TDU6] synonym: "BG37" EXACT [UniProtKB:Q8TDU6] synonym: "hBG37" EXACT [UniProtKB:Q8TDU6] synonym: "hGPCR19" EXACT [UniProtKB:Q8TDU6] synonym: "M-BAR" EXACT [UniProtKB:Q8TDU6] synonym: "Membrane-type receptor for bile acids" EXACT [UniProtKB:Q8TDU6] xref: EMBL:AAH33625.1 xref: EMBL:BAB89314.1 xref: EMBL:BAC55235.1 xref: EMBL:BAC65343.1 xref: UniProtKB:Q8TDU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017992 ! GPBAR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057940 name: RL3R2_HUMAN def: "Relaxin-3 receptor 2" [UniProtKB:Q8TDU9] synonym: "G-protein coupled receptor 100" EXACT [UniProtKB:Q8TDU9] synonym: "GPCR142" EXACT [UniProtKB:Q8TDU9] synonym: "Relaxin family peptide receptor 4" EXACT [UniProtKB:Q8TDU9] xref: EMBL:AAI01508.1 xref: EMBL:AAI01510.1 xref: EMBL:AAO17676.1 xref: EMBL:AAP72124.1 xref: EMBL:AAQ92316.1 xref: EMBL:BAB89306.1 xref: EMBL:BAC05844.1 xref: EMBL:CAH72626.1 xref: UniProtKB:Q3MJB1 xref: UniProtKB:Q8NGZ8 xref: UniProtKB:Q8TDU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019750 ! RXFP4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001287 ! angiotensin type II receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057941 name: GP151_HUMAN def: "Probable G-protein coupled receptor 151" [UniProtKB:Q8TDV0] synonym: "G-protein coupled receptor PGR7" EXACT [UniProtKB:Q8TDV0] synonym: "GPCR-2037" EXACT [UniProtKB:Q8TDV0] xref: EMBL:AAO85069.1 xref: EMBL:AAQ62567.1 xref: EMBL:BAB89305.1 xref: EMBL:BAC05899.1 xref: UniProtKB:Q86SN8 xref: UniProtKB:Q8NGV2 xref: UniProtKB:Q8TDV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017975 ! GPR151_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057942 name: Q8TDV1_HUMAN def: "Putative G-protein coupled receptor" [UniProtKB:Q8TDV1] xref: EMBL:BAB89304.1 xref: UniProtKB:Q8TDV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021210 ! GPCR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057943 name: GP148_HUMAN def: "Probable G-protein coupled receptor 148" [UniProtKB:Q8TDV2] synonym: "Brain and testis restricted GPCR" EXACT [UniProtKB:Q8TDV2] synonym: "G-protein coupled receptor PGR6" EXACT [UniProtKB:Q8TDV2] xref: EMBL:AAI05014.1 xref: EMBL:AAI05042.1 xref: EMBL:AAO85044.1 xref: EMBL:AAP34196.1 xref: EMBL:AAS76892.1 xref: EMBL:BAB89302.1 xref: UniProtKB:Q2M369 xref: UniProtKB:Q86SP7 xref: UniProtKB:Q86U87 xref: UniProtKB:Q8TDV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017972 ! GPR148_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057944 name: GP119_HUMAN def: "Glucose-dependent insulinotropic receptor" [UniProtKB:Q8TDV5] synonym: "G-protein coupled receptor 119" EXACT [UniProtKB:Q8TDV5] xref: EMBL:AAH95502.1 xref: EMBL:AAI01167.1 xref: EMBL:AAI01168.1 xref: EMBL:AAI01169.1 xref: EMBL:AAI26180.1 xref: EMBL:AAI26182.1 xref: EMBL:AAP72125.1 xref: EMBL:BAB89297.1 xref: EMBL:BAC06151.1 xref: EMBL:CAI42442.1 xref: UniProtKB:Q495H7 xref: UniProtKB:Q4VBN3 xref: UniProtKB:Q8TDV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017960 ! GPR119_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057945 name: CGAT1_HUMAN def: "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" [UniProtKB:Q8TDX6] synonym: "Beta4GalNAcT-1" EXACT [UniProtKB:Q8TDX6] synonym: "Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1" EXACT [UniProtKB:Q8TDX6] synonym: "CsGalNAcT-1" EXACT [UniProtKB:Q8TDX6] synonym: "EC 2.4.1.174" EXACT [UniProtKB:Q8TDX6] xref: EMBL:AAH60772.1 xref: EMBL:AAQ88806.1 xref: EMBL:BAA92093.1 xref: EMBL:BAB85992.1 xref: EMBL:BAC16217.1 xref: EMBL:CAB75673.1 xref: UniProtKB:Q6P9G6 xref: UniProtKB:Q8IUF9 xref: UniProtKB:Q8TDX6 xref: UniProtKB:Q9NSQ7 xref: UniProtKB:Q9NUM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017342 ! CSGALNACT1_human relationship: has_function CCO:F0001852 ! acetylgalactosaminyltransferase activity relationship: has_function CCO:F0002289 ! peptidoglycan glycosyltransferase activity relationship: has_function CCO:F0002526 ! glucuronosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006548 ! glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity relationship: has_function CCO:F0006549 ! glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000988 ! integral to Golgi membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0057946 name: DDFL1_HUMAN def: "Development and differentiation-enhancing factor-like 1" [UniProtKB:Q8TDY4] synonym: "Protein up-regulated in liver cancer 1" EXACT [UniProtKB:Q8TDY4] xref: EMBL:AAH52305.1 xref: EMBL:AAH60786.1 xref: EMBL:BAA91008.1 xref: EMBL:BAB85677.1 xref: EMBL:CAI19596.1 xref: EMBL:CAI22177.1 xref: UniProtKB:Q6P9F4 xref: UniProtKB:Q86UY1 xref: UniProtKB:Q8TDY4 xref: UniProtKB:Q9NXK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017541 ! DDEFL1_human relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0057947 name: MICA1_HUMAN def: "NEDD9-interacting protein with calponin homology and LIM domains" [UniProtKB:Q8TDZ2] synonym: "Molecule interacting with CasL protein 1" EXACT [UniProtKB:Q8TDZ2] xref: EMBL:AAH09972.2 xref: EMBL:AAH42144.1 xref: EMBL:AAH52983.1 xref: EMBL:BAB13949.1 xref: EMBL:BAB15124.1 xref: EMBL:BAB15790.1 xref: EMBL:BAB86289.1 xref: EMBL:CAB59266.1 xref: EMBL:CAI23343.1 xref: UniProtKB:Q7Z633 xref: UniProtKB:Q8IVS9 xref: UniProtKB:Q8TDZ2 xref: UniProtKB:Q96G47 xref: UniProtKB:Q9H6X6 xref: UniProtKB:Q9H7I0 xref: UniProtKB:Q9HAA1 xref: UniProtKB:Q9UFF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018619 ! MICAL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068171 ! MICA1_HUMAN-Phosphoserine872 relationship: transforms_into CCO:B0068172 ! MICA1_HUMAN-Phosphoserine875 relationship: transforms_into CCO:B0068173 ! MICA1_HUMAN-Phosphoserine876 [Term] id: CCO:B0057948 name: DERP6_HUMAN def: "Dermal papilla-derived protein 6" [UniProtKB:Q8TE02] synonym: "S-phase 2 protein" EXACT [UniProtKB:Q8TE02] xref: EMBL:AAD20964.1 xref: EMBL:AAH02762.2 xref: EMBL:AAM10496.1 xref: EMBL:AAQ13591.1 xref: EMBL:BAB87800.1 xref: EMBL:CAH56280.1 xref: UniProtKB:Q659B6 xref: UniProtKB:Q7Z2T4 xref: UniProtKB:Q8TDR9 xref: UniProtKB:Q8TE02 xref: UniProtKB:Q9BUB2 xref: UniProtKB:Q9Y2Q4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017561 ! DERP6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016186 ! atxn1-derp6 physical interaction relationship: participates_in CCO:I0019089 ! atxn1-derp6-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057949 name: LMX1A_HUMAN def: "LIM homeobox transcription factor 1-alpha" [UniProtKB:Q8TE12] synonym: "LIM/homeobox protein 1.1" EXACT [UniProtKB:Q8TE12] synonym: "LIM/homeobox protein LMX1A" EXACT [UniProtKB:Q8TE12] synonym: "LMX-1.1" EXACT [UniProtKB:Q8TE12] xref: EMBL:AAL82892.1 xref: EMBL:AAL82893.1 xref: EMBL:CAH71967.1 xref: EMBL:CAH73258.1 xref: UniProtKB:Q5VWG4 xref: UniProtKB:Q8TE11 xref: UniProtKB:Q8TE12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018511 ! LMX1A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057950 name: TS1R2_HUMAN def: "Taste receptor type 1 member 2 precursor" [UniProtKB:Q8TE23] synonym: "G-protein coupled receptor 71" EXACT [UniProtKB:Q8TE23] synonym: "Sweet taste receptor T1R2" EXACT [UniProtKB:Q8TE23] xref: EMBL:AAM12239.1 xref: EMBL:CAH69954.1 xref: EMBL:CAI17299.1 xref: EMBL:DAA00019.1 xref: UniProtKB:Q5TZ19 xref: UniProtKB:Q8TE23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020366 ! TAS1R2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_function CCO:F0005058 ! sweet taste receptor activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057951 name: GRHL3_HUMAN def: "Grainyhead-like protein 3 homolog" [UniProtKB:Q8TE85] synonym: "Sister of mammalian grainyhead" EXACT [UniProtKB:Q8TE85] synonym: "Transcription factor CP2-like 4" EXACT [UniProtKB:Q8TE85] xref: EMBL:AAH36890.1 xref: EMBL:AAO67370.1 xref: EMBL:BAB85067.1 xref: EMBL:CAI21406.2 xref: EMBL:CAI21407.2 xref: EMBL:CAI22857.2 xref: EMBL:CAI22858.2 xref: UniProtKB:Q5TH78 xref: UniProtKB:Q86Y06 xref: UniProtKB:Q8N407 xref: UniProtKB:Q8TE85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018059 ! GRHL3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057952 name: Q8TEA3_HUMAN def: "cDNA FLJ23738 fis, clone HEP15081, highly similar to PDZ domain-containing guanine nucleotide exchange factor I" [UniProtKB:Q8TEA3] xref: EMBL:BAB85049.1 xref: UniProtKB:Q8TEA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0057953 name: TBCK_HUMAN def: "TBC domain-containing protein kinase-like protein" [UniProtKB:Q8TEA7] xref: EMBL:AAF28980.1 xref: EMBL:AAH09208.2 xref: EMBL:AAH20853.2 xref: EMBL:AAH68496.1 xref: EMBL:AAY40979.1 xref: EMBL:AAY41041.1 xref: EMBL:BAB85045.1 xref: EMBL:BAC05244.1 xref: UniProtKB:Q4W5B3 xref: UniProtKB:Q4W5E1 xref: UniProtKB:Q6NUP4 xref: UniProtKB:Q8N7M8 xref: UniProtKB:Q8TEA7 xref: UniProtKB:Q8WW57 xref: UniProtKB:Q96GV6 xref: UniProtKB:Q9P080 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020185 ! TBCK_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0057954 name: RN128_HUMAN def: "E3 ubiquitin-protein ligase RNF128 precursor" [UniProtKB:Q8TEB7] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8TEB7] synonym: "Gene related to anergy in lymphocytes protein" EXACT [UniProtKB:Q8TEB7] synonym: "RING finger protein 128" EXACT [UniProtKB:Q8TEB7] xref: EMBL:AAH56677.1 xref: EMBL:AAH63404.1 xref: EMBL:AAK77554.1 xref: EMBL:BAB15682.1 xref: EMBL:BAB85033.1 xref: EMBL:BAC86589.1 xref: EMBL:CAI39545.1 xref: EMBL:CAI39546.1 xref: EMBL:CAI41228.1 xref: UniProtKB:Q6PH80 xref: UniProtKB:Q6ZTJ8 xref: UniProtKB:Q8TEB7 xref: UniProtKB:Q96RF3 xref: UniProtKB:Q9H5E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019756 ! RNF128_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002031 ! negative regulation of cytokine biosynthetic process [Term] id: CCO:B0057955 name: SOLO_HUMAN def: "Protein SOLO" [UniProtKB:Q8TER5] xref: EMBL:AAH00084.3 xref: EMBL:AAI42693.1 xref: EMBL:BAA91563.1 xref: EMBL:BAB15753.1 xref: EMBL:BAB84883.1 xref: EMBL:CAB70682.1 xref: UniProtKB:A5PL07 xref: UniProtKB:Q8TER5 xref: UniProtKB:Q9BWP5 xref: UniProtKB:Q9H7L6 xref: UniProtKB:Q9NTF9 xref: UniProtKB:Q9NW24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019980 ! SOLO_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0070720 ! SOLO_HUMAN-Phosphoserine931 [Term] id: CCO:B0057956 name: RPGF6_HUMAN def: "Rap guanine nucleotide exchange factor 6" [UniProtKB:Q8TEU7] synonym: "PDZ domain-containing guanine nucleotide exchange factor 2" EXACT [UniProtKB:Q8TEU7] synonym: "PDZ-GEF2" EXACT [UniProtKB:Q8TEU7] synonym: "RA-GEF-2" EXACT [UniProtKB:Q8TEU7] xref: EMBL:AAK83368.1 xref: EMBL:AAL79915.1 xref: EMBL:AAL79916.1 xref: EMBL:AAM21637.1 xref: UniProtKB:Q8NI21 xref: UniProtKB:Q8TEU6 xref: UniProtKB:Q8TEU7 xref: UniProtKB:Q96PC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019789 ! RAPGEF6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0070169 ! RPGF6_HUMAN-Phosphothreonine496 relationship: transforms_into CCO:B0070170 ! RPGF6_HUMAN-Phosphoserine1070 relationship: transforms_into CCO:B0070171 ! RPGF6_HUMAN-Phosphoserine1494 relationship: transforms_into CCO:B0070172 ! RPGF6_HUMAN-Phosphothreonine1507 [Term] id: CCO:B0057957 name: DOK4_HUMAN def: "Docking protein 4" [UniProtKB:Q8TEW6] synonym: "Downstream of tyrosine kinase 4" EXACT [UniProtKB:Q8TEW6] xref: EMBL:AAC24310.1 xref: EMBL:AAH01540.1 xref: EMBL:AAH03541.1 xref: EMBL:AAL74195.1 xref: EMBL:BAA91642.1 xref: UniProtKB:O75209 xref: UniProtKB:Q8TEW6 xref: UniProtKB:Q9BTP2 xref: UniProtKB:Q9NVV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017604 ! DOK4_human relationship: has_function CCO:F0001377 ! transmembrane receptor protein tyrosine kinase signaling protein activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0057958 name: CR3L4_HUMAN def: "cAMP-responsive element-binding protein 3-like protein 4" [UniProtKB:Q8TEY5] synonym: "AIbZIP" EXACT [UniProtKB:Q8TEY5] synonym: "Androgen-induced basic leucine zipper protein" EXACT [UniProtKB:Q8TEY5] synonym: "ATCE1" EXACT [UniProtKB:Q8TEY5] synonym: "Attaching to CRE-like 1" EXACT [UniProtKB:Q8TEY5] synonym: "Cyclic AMP-responsive element-binding protein 4" EXACT [UniProtKB:Q8TEY5] synonym: "hJAL" EXACT [UniProtKB:Q8TEY5] synonym: "Tisp40" EXACT [UniProtKB:Q8TEY5] synonym: "Transcript induced in spermiogenesis protein 40" EXACT [UniProtKB:Q8TEY5] xref: EMBL:AAH38962.1 xref: EMBL:AAL13157.1 xref: EMBL:AAL76113.1 xref: EMBL:AAO33070.1 xref: EMBL:BAC45035.1 xref: EMBL:BAC45224.1 xref: EMBL:CAI14027.1 xref: UniProtKB:Q86YW6 xref: UniProtKB:Q8TEY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017449 ! CREB3L4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0057959 name: PP4R1_HUMAN def: "Serine/threonine-protein phosphatase 4 regulatory subunit 1" [UniProtKB:Q8TF05] xref: EMBL:AAB50211.1 xref: EMBL:AAD09818.1 xref: EMBL:AAD43008.1 xref: EMBL:AAH60829.1 xref: EMBL:AAL78298.1 xref: UniProtKB:Q8TF05 xref: UniProtKB:Q99774 xref: UniProtKB:Q9UNQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019478 ! PPP4R1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004410 ! protein phosphatase type 4 regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0017443 ! disc1-ppp4r1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057960 name: ZN721_HUMAN def: "Zinc finger protein 721" [UniProtKB:Q8TF20] xref: EMBL:BAB85568.1 xref: EMBL:CAH10687.1 xref: UniProtKB:Q69YG7 xref: UniProtKB:Q8TF20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020919 ! ZNF721_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057961 name: CTLFX_HUMAN def: "Centaurin-gamma-like protein KIAA1975" [UniProtKB:Q8TF27] xref: EMBL:BAB85561.1 xref: UniProtKB:Q8TF27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008895 ! KIAA1975_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0057962 name: ZN483_HUMAN def: "Zinc finger protein 483" [UniProtKB:Q8TF39] synonym: "Zinc finger protein with KRAB and SCAN domains 16" EXACT [UniProtKB:Q8TF39] xref: EMBL:AAI36696.1 xref: EMBL:AAI36697.1 xref: EMBL:BAB85548.1 xref: EMBL:BAF83956.1 xref: EMBL:CAH73468.1 xref: EMBL:EAW59073.1 xref: UniProtKB:Q5VZN2 xref: UniProtKB:Q8TF39 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020769 ! ZNF483_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057963 name: ZN418_HUMAN def: "Zinc finger protein 418" [UniProtKB:Q8TF45] xref: EMBL:AAI12245.1 xref: EMBL:AAI13708.1 xref: EMBL:AAU05132.1 xref: EMBL:BAB71096.1 xref: EMBL:BAB85542.1 xref: UniProtKB:Q2M1S2 xref: UniProtKB:Q670L5 xref: UniProtKB:Q8TF45 xref: UniProtKB:Q96N18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020741 ! ZNF418_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057964 name: ZFP90_HUMAN def: "Zinc finger protein 90 homolog" [UniProtKB:Q8TF47] synonym: "Zfp-90" EXACT [UniProtKB:Q8TF47] xref: EMBL:AAH33165.1 xref: EMBL:AAH40486.1 xref: EMBL:BAB71228.1 xref: EMBL:BAB85540.1 xref: UniProtKB:Q49AD1 xref: UniProtKB:Q8TF47 xref: UniProtKB:Q96MQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020594 ! ZFP90_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057965 name: ZN526_HUMAN def: "Zinc finger protein 526" [UniProtKB:Q8TF50] xref: EMBL:AAH13013.1 xref: EMBL:BAB85537.1 xref: EMBL:CAH10586.1 xref: UniProtKB:Q69YI2 xref: UniProtKB:Q8TF50 xref: UniProtKB:Q96E24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020797 ! ZNF526_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057966 name: ZN384_HUMAN def: "Zinc finger protein 384" [UniProtKB:Q8TF68] synonym: "CAG repeat protein 1" EXACT [UniProtKB:Q8TF68] synonym: "CAS-interacting zinc finger protein" EXACT [UniProtKB:Q8TF68] synonym: "Nuclear matrix protein 4" EXACT [UniProtKB:Q8TF68] synonym: "Nuclear matrix transcription factor 4" EXACT [UniProtKB:Q8TF68] synonym: "Trinucleotide repeat-containing gene 1 protein" EXACT [UniProtKB:Q8TF68] xref: EMBL:AAB91437.1 xref: EMBL:BAB85125.1 xref: EMBL:BAC04618.1 xref: UniProtKB:O15407 xref: UniProtKB:Q8N938 xref: UniProtKB:Q8TF68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020725 ! ZNF384_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072117 ! ZN384_HUMAN-Phosphoserine214 [Term] id: CCO:B0057967 name: SHRM3_HUMAN def: "Protein Shroom3" [UniProtKB:Q8TF72] synonym: "hShrmL" EXACT [UniProtKB:Q8TF72] synonym: "Shroom" EXACT [UniProtKB:Q8TF72] synonym: "Shroom-related protein" EXACT [UniProtKB:Q8TF72] xref: EMBL:AAH07291.1 xref: EMBL:AAQ13515.1 xref: EMBL:BAA96005.1 xref: EMBL:BAB84689.1 xref: EMBL:BAC87195.1 xref: UniProtKB:Q5QTQ3 xref: UniProtKB:Q6ZRW3 xref: UniProtKB:Q8TF72 xref: UniProtKB:Q96IR9 xref: UniProtKB:Q9P247 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019901 ! SHROOM3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0070511 ! SHRM3_HUMAN-Phosphoserine438 relationship: transforms_into CCO:B0070512 ! SHRM3_HUMAN-Phosphoserine442 relationship: transforms_into CCO:B0070513 ! SHRM3_HUMAN-Phosphothreonine575 relationship: transforms_into CCO:B0070514 ! SHRM3_HUMAN-Phosphoserine581 relationship: transforms_into CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 relationship: transforms_into CCO:B0070516 ! SHRM3_HUMAN-Phosphoserine889 relationship: transforms_into CCO:B0070517 ! SHRM3_HUMAN-Phosphoserine909 relationship: transforms_into CCO:B0070518 ! SHRM3_HUMAN-Phosphoserine912 relationship: transforms_into CCO:B0070519 ! SHRM3_HUMAN-Phosphoserine1220 [Term] id: CCO:B0057968 name: GRK7_HUMAN def: "G protein-coupled receptor kinase 7 precursor" [UniProtKB:Q8WTQ7] synonym: "EC 2.7.11.16" EXACT [UniProtKB:Q8WTQ7] synonym: "G protein-coupled receptor kinase GRK7" EXACT [UniProtKB:Q8WTQ7] xref: EMBL:AAL33880.1 xref: EMBL:AAL48216.1 xref: UniProtKB:Q8WTQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018074 ! GRK7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0066623 ! GRK7_HUMAN-Cysteine methyl ester550 [Term] id: CCO:B0057969 name: DUS19_HUMAN def: "Dual specificity protein phosphatase 19" [UniProtKB:Q8WTR2] synonym: "Dual-specificity phosphatase TS-DSP1" EXACT [UniProtKB:Q8WTR2] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q8WTR2] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q8WTR2] synonym: "LMW-DSP3" EXACT [UniProtKB:Q8WTR2] synonym: "Protein phosphatase SKRP1" EXACT [UniProtKB:Q8WTR2] synonym: "SAPK pathway-regulating phosphatase 1" EXACT [UniProtKB:Q8WTR2] synonym: "Stress-activated protein kinase pathway-regulating phosphatase 1" EXACT [UniProtKB:Q8WTR2] xref: EMBL:AAH35000.1 xref: EMBL:AAH93958.1 xref: EMBL:AAI12006.1 xref: EMBL:AAO49450.1 xref: EMBL:AAY24197.1 xref: EMBL:BAB82499.1 xref: EMBL:BAB83498.1 xref: EMBL:BAB83499.1 xref: UniProtKB:Q547H4 xref: UniProtKB:Q8WTR2 xref: UniProtKB:Q8WYN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017633 ! DUSP19_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0001839 ! protein tyrosine/threonine phosphatase activity relationship: has_function CCO:F0002002 ! JUN kinase phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000772 ! JNK cascade [Term] id: CCO:B0057970 name: Q8WTR3_HUMAN def: "Dopamine receptor D4" [UniProtKB:Q8WTR3] xref: EMBL:AAL35178.1 xref: EMBL:AAL35183.1 xref: UniProtKB:Q8WTR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017620 ! DRD4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0057971 name: ZN473_HUMAN def: "Zinc finger protein 473" [UniProtKB:Q8WTR7] synonym: "Zfp-100" EXACT [UniProtKB:Q8WTR7] synonym: "Zinc finger protein 100 homolog" EXACT [UniProtKB:Q8WTR7] xref: EMBL:AAH18612.1 xref: EMBL:AAL51029.1 xref: EMBL:BAA86455.1 xref: EMBL:CAB45736.1 xref: UniProtKB:Q8WTR7 xref: UniProtKB:Q9ULS9 xref: UniProtKB:Q9Y4Q7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020767 ! ZNF473_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015714 ! trim41-znf473 physical interaction relationship: participates_in CCO:I0015803 ! znf202-znf473 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057972 name: SETD7_HUMAN def: "Histone-lysine N-methyltransferase SETD7" [UniProtKB:Q8WTS6] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q8WTS6] synonym: "H3-K4-HMTase SETD7" EXACT [UniProtKB:Q8WTS6] synonym: "Histone H3-K4 methyltransferase SETD7" EXACT [UniProtKB:Q8WTS6] synonym: "Lysine N-methyltransferase 7" EXACT [UniProtKB:Q8WTS6] synonym: "SET domain-containing protein 7" EXACT [UniProtKB:Q8WTS6] synonym: "SET7/9" EXACT [UniProtKB:Q8WTS6] xref: EMBL:AAI21056.1 xref: EMBL:AAI21057.1 xref: EMBL:AAL69901.1 xref: EMBL:AAY40937.1 xref: EMBL:BAB21808.1 xref: UniProtKB:Q0VAH3 xref: UniProtKB:Q4W5A9 xref: UniProtKB:Q8WTS6 xref: UniProtKB:Q9C0E6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019870 ! SETD7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057973 name: YS049_HUMAN def: "Zinc finger protein ENSP00000375192" [UniProtKB:Q8WTZ3] xref: EMBL:AAH21822.1 xref: UniProtKB:Q8WTZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057974 name: RN139_HUMAN def: "RING finger protein 139" [UniProtKB:Q8WU17] synonym: "Translocation in renal carcinoma on chromosome 8" EXACT [UniProtKB:Q8WU17] xref: EMBL:AAC39930.1 xref: EMBL:AAC39931.1 xref: EMBL:AAH21571.1 xref: EMBL:AAH64636.1 xref: UniProtKB:O75485 xref: UniProtKB:Q7LDL3 xref: UniProtKB:Q8WU17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019757 ! RNF139_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001430 ! regulation of protein ubiquitination relationship: transforms_into CCO:B0070101 ! RN139_HUMAN-Phosphoserine625 relationship: transforms_into CCO:B0070102 ! RN139_HUMAN-Phosphoserine634 relationship: transforms_into CCO:B0070103 ! RN139_HUMAN-Phosphothreonine635 relationship: transforms_into CCO:B0070104 ! RN139_HUMAN-Phosphothreonine663 [Term] id: CCO:B0057975 name: FRS2_HUMAN def: "Fibroblast growth factor receptor substrate 2" [UniProtKB:Q8WU20] synonym: "FGFR substrate 2" EXACT [UniProtKB:Q8WU20] synonym: "FGFR-signaling adaptor SNT" EXACT [UniProtKB:Q8WU20] synonym: "SNT-1" EXACT [UniProtKB:Q8WU20] synonym: "Suc1-associated neurotrophic factor target 1" EXACT [UniProtKB:Q8WU20] xref: EMBL:AAB92554.1 xref: EMBL:AAH21562.1 xref: EMBL:ABY87531.1 xref: EMBL:BAG35381.1 xref: EMBL:EAW97225.1 xref: UniProtKB:B0LPF2 xref: UniProtKB:B2R684 xref: UniProtKB:O43558 xref: UniProtKB:Q7LDQ6 xref: UniProtKB:Q8WU20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017834 ! FRS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000725 ! transmembrane receptor protein tyrosine phosphatase signaling pathway relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: transforms_into CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 [Term] id: CCO:B0057976 name: PHF10_HUMAN def: "PHD finger protein 10" [UniProtKB:Q8WUB8] synonym: "XAP135" EXACT [UniProtKB:Q8WUB8] xref: EMBL:AAH20954.1 xref: EMBL:AAI10324.1 xref: EMBL:AAK27451.1 xref: EMBL:BAA91934.1 xref: EMBL:CAG33554.1 xref: EMBL:CAI12316.1 xref: UniProtKB:Q2YDA3 xref: UniProtKB:Q8WUB8 xref: UniProtKB:Q9BXD2 xref: UniProtKB:Q9NV26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019378 ! PHF10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014987 ! l3mbtl2-phf10 physical interaction relationship: participates_in CCO:I0020107 ! phf10-utp14a physical interaction relationship: participates_in CCO:I0020108 ! phf10-setdb1 physical interaction relationship: participates_in CCO:I0020109 ! phf10-unc119 physical interaction relationship: participates_in CCO:I0020400 ! phf10-aplp1 physical interaction relationship: participates_in CCO:I0020530 ! celsr2-phf10 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069248 ! PHF10_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0069249 ! PHF10_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0069250 ! PHF10_HUMAN-Phosphoserine213 [Term] id: CCO:B0057977 name: RAB2B_HUMAN def: "Ras-related protein Rab-2B" [UniProtKB:Q8WUD1] xref: EMBL:AAH20839.1 xref: EMBL:AAN86142.1 xref: UniProtKB:Q8WUD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019586 ! RAB2B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057978 name: CHPT1_HUMAN def: "Cholinephosphotransferase 1" [UniProtKB:Q8WUD6] synonym: "AAPT1-like protein" EXACT [UniProtKB:Q8WUD6] synonym: "Diacylglycerol cholinephosphotransferase 1" EXACT [UniProtKB:Q8WUD6] synonym: "EC 2.7.8.2" EXACT [UniProtKB:Q8WUD6] synonym: "hCPT1" EXACT [UniProtKB:Q8WUD6] xref: EMBL:AAD44019.1 xref: EMBL:AAF87947.1 xref: EMBL:AAF87948.1 xref: EMBL:AAH20819.1 xref: EMBL:AAH50429.1 xref: EMBL:AAL39005.1 xref: EMBL:AAN86122.1 xref: EMBL:AAN86123.1 xref: EMBL:AAP34412.1 xref: EMBL:AAP34413.1 xref: EMBL:AAP37157.1 xref: UniProtKB:Q7Z7H0 xref: UniProtKB:Q7Z7H1 xref: UniProtKB:Q7Z7H2 xref: UniProtKB:Q8IWQ4 xref: UniProtKB:Q8IWQ5 xref: UniProtKB:Q8WUD6 xref: UniProtKB:Q8WYI4 xref: UniProtKB:Q9NRQ6 xref: UniProtKB:Q9NRQ7 xref: UniProtKB:Q9Y6M6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017358 ! CHPT1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000613 ! diacylglycerol cholinephosphotransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0057979 name: IASPP_HUMAN def: "RelA-associated inhibitor" [UniProtKB:Q8WUF5] synonym: "Inhibitor of ASPP protein" EXACT [UniProtKB:Q8WUF5] synonym: "NFkB-interacting protein 1" EXACT [UniProtKB:Q8WUF5] synonym: "PPP1R13B-like protein" EXACT [UniProtKB:Q8WUF5] synonym: "Protein iASPP" EXACT [UniProtKB:Q8WUF5] xref: EMBL:AAD27004.1 xref: EMBL:AAD27005.1 xref: EMBL:AAH01475.1 xref: EMBL:AAH20589.1 xref: EMBL:AAH32298.1 xref: EMBL:AAH64913.1 xref: EMBL:AAW51146.1 xref: EMBL:ABC40745.1 xref: EMBL:CAI60219.1 xref: UniProtKB:Q2PNZ9 xref: UniProtKB:Q5DU71 xref: UniProtKB:Q5I1X4 xref: UniProtKB:Q6P1R7 xref: UniProtKB:Q6PKF8 xref: UniProtKB:Q8WUF5 xref: UniProtKB:Q9Y290 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011813 ! PPP1R13L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066980 ! IASPP_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0066981 ! IASPP_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0066982 ! IASPP_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0066983 ! IASPP_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0066984 ! IASPP_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0066985 ! IASPP_HUMAN-Phosphothreonine123 relationship: transforms_into CCO:B0066986 ! IASPP_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0066987 ! IASPP_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0066988 ! IASPP_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0066989 ! IASPP_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0066990 ! IASPP_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0066991 ! IASPP_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0066992 ! IASPP_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0066993 ! IASPP_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0066994 ! IASPP_HUMAN-Phosphoserine526 relationship: transforms_into CCO:B0066995 ! IASPP_HUMAN-Phosphoserine567 relationship: transforms_into CCO:B0066996 ! IASPP_HUMAN-Phosphoserine597 [Term] id: CCO:B0057980 name: CHUR_HUMAN def: "Protein Churchill" [UniProtKB:Q8WUH1] xref: EMBL:AAG43128.1 xref: EMBL:AAH20550.1 xref: UniProtKB:Q8WUH1 xref: UniProtKB:Q9H3K7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017359 ! CHURC1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0057981 name: Q8WUM3_HUMAN xref: UniProtKB:Q8WUM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057982 name: S20A1_HUMAN def: "Sodium-dependent phosphate transporter 1" [UniProtKB:Q8WUM9] synonym: "Gibbon ape leukemia virus receptor 1" EXACT [UniProtKB:Q8WUM9] synonym: "GLVR-1" EXACT [UniProtKB:Q8WUM9] synonym: "Leukemia virus receptor 1 homolog" EXACT [UniProtKB:Q8WUM9] synonym: "Phosphate transporter 1" EXACT [UniProtKB:Q8WUM9] synonym: "PiT-1" EXACT [UniProtKB:Q8WUM9] synonym: "Solute carrier family 20 member 1" EXACT [UniProtKB:Q8WUM9] xref: EMBL:AAA52572.1 xref: EMBL:AAD20286.1 xref: EMBL:AAH19944.1 xref: EMBL:AAH75818.1 xref: EMBL:AAY14922.1 xref: UniProtKB:Q08344 xref: UniProtKB:Q6DHX8 xref: UniProtKB:Q8WUM9 xref: UniProtKB:Q9UQ82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019821 ! SLC20A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0070277 ! S20A1_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0070278 ! S20A1_HUMAN-Phosphoserine269 [Term] id: CCO:B0057983 name: ZN296_HUMAN def: "Zinc finger protein 296" [UniProtKB:Q8WUU4] synonym: "Zinc finger protein 342" EXACT [UniProtKB:Q8WUU4] xref: EMBL:AAH19352.1 xref: UniProtKB:Q8WUU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022805 ! ZNF296_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057984 name: GATD1_HUMAN def: "GATA zinc finger domain-containing protein 1" [UniProtKB:Q8WUU5] synonym: "Ocular development-associated gene protein" EXACT [UniProtKB:Q8WUU5] xref: EMBL:AAB46345.1 xref: EMBL:AAH19350.1 xref: EMBL:AAH31091.1 xref: EMBL:BAB15374.1 xref: EMBL:EAL24150.1 xref: UniProtKB:Q8N5Y5 xref: UniProtKB:Q8WUU5 xref: UniProtKB:Q99995 xref: UniProtKB:Q9H689 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017875 ! GATAD1_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057985 name: NAT14_HUMAN def: "N-acetyltransferase 14" [UniProtKB:Q8WUY8] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q8WUY8] synonym: "K562 cell-derived leucine-zipper-like protein 1" EXACT [UniProtKB:Q8WUY8] xref: EMBL:AAH19079.1 xref: EMBL:BAB03716.1 xref: EMBL:BAB85857.1 xref: UniProtKB:Q8TDY7 xref: UniProtKB:Q8WUY8 xref: UniProtKB:Q9NS72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018722 ! NAT14_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057986 name: DEP1B_HUMAN def: "DEP domain-containing protein 1B" [UniProtKB:Q8WUY9] synonym: "HBV X-transactivated gene 8 protein" EXACT [UniProtKB:Q8WUY9] xref: EMBL:AAH10904.1 xref: EMBL:AAH19075.1 xref: EMBL:AAN31126.1 xref: EMBL:AAO49477.1 xref: EMBL:AAO85465.1 xref: EMBL:BAA91529.1 xref: EMBL:BAA92089.1 xref: UniProtKB:Q86WJ3 xref: UniProtKB:Q8IZY6 xref: UniProtKB:Q8WUY9 xref: UniProtKB:Q9NUN3 xref: UniProtKB:Q9NW57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017554 ! DEPDC1B_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0057987 name: ZN688_HUMAN def: "Zinc finger protein 688" [UniProtKB:P0C7X2] xref: EMBL:AAC31673.1 xref: EMBL:AAH18997.1 xref: UniProtKB:O75701 xref: UniProtKB:P0C7X2 xref: UniProtKB:Q8IW91 xref: UniProtKB:Q8WV14 xref: UniProtKB:Q96MN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020899 ! ZNF688_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057988 name: BLNK_HUMAN def: "B-cell linker protein" [UniProtKB:Q8WV28] synonym: "B-cell adapter containing a SH2 domain protein" EXACT [UniProtKB:Q8WV28] synonym: "B-cell adapter containing a Src homology 2 domain protein" EXACT [UniProtKB:Q8WV28] synonym: "Cytoplasmic adapter protein" EXACT [UniProtKB:Q8WV28] synonym: "SLP-65" EXACT [UniProtKB:Q8WV28] synonym: "Src homology 2 domain-containing leukocyte protein of 65 kDa" EXACT [UniProtKB:Q8WV28] xref: EMBL:AAC39936.1 xref: EMBL:AAC39937.1 xref: EMBL:AAF20382.1 xref: EMBL:AAF20383.1 xref: EMBL:AAH18906.1 xref: UniProtKB:O75498 xref: UniProtKB:O75499 xref: UniProtKB:Q8WV28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017164 ! BLNK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0063936 ! BLNK_HUMAN-Phosphotyrosine72 relationship: transforms_into CCO:B0063937 ! BLNK_HUMAN-Phosphotyrosine84 relationship: transforms_into CCO:B0063938 ! BLNK_HUMAN-Phosphotyrosine96 relationship: transforms_into CCO:B0063939 ! BLNK_HUMAN-Phosphotyrosine178 relationship: transforms_into CCO:B0063940 ! BLNK_HUMAN-Phosphotyrosine189 [Term] id: CCO:B0057989 name: ZN480_HUMAN def: "Zinc finger protein 480" [UniProtKB:Q8WV37] xref: EMBL:AAH18783.1 xref: EMBL:AAH65503.1 xref: EMBL:AAR97581.1 xref: EMBL:BAC04792.1 xref: EMBL:BAC04817.1 xref: EMBL:CAI46140.1 xref: UniProtKB:Q5JPG9 xref: UniProtKB:Q6P0Q4 xref: UniProtKB:Q8N1M5 xref: UniProtKB:Q8WV37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020768 ! ZNF480_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057990 name: LEO1_HUMAN def: "RNA polymerase-associated protein LEO1" [UniProtKB:Q8WVC0] synonym: "Replicative senescence down-regulated leo1-like protein" EXACT [UniProtKB:Q8WVC0] xref: EMBL:AAH18147.1 xref: EMBL:AAP68819.1 xref: EMBL:BAB71006.1 xref: UniProtKB:Q8WVC0 xref: UniProtKB:Q96N99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018472 ! LEO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017916 ! leo1-ctnnb1-5 physical interaction relationship: participates_in CCO:I0019296 ! leo1-ctnnb1-4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067613 ! LEO1_HUMAN-Phosphoserine10 relationship: transforms_into CCO:B0067614 ! LEO1_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0067615 ! LEO1_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0067616 ! LEO1_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0067617 ! LEO1_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0067618 ! LEO1_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0067619 ! LEO1_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0067620 ! LEO1_HUMAN-Phosphothreonine188 relationship: transforms_into CCO:B0067621 ! LEO1_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0067622 ! LEO1_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0067623 ! LEO1_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0067624 ! LEO1_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0067625 ! LEO1_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0067626 ! LEO1_HUMAN-Phosphoserine238 relationship: transforms_into CCO:B0067627 ! LEO1_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0067628 ! LEO1_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0067629 ! LEO1_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0067630 ! LEO1_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0067631 ! LEO1_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0067632 ! LEO1_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0067633 ! LEO1_HUMAN-Phosphothreonine302 relationship: transforms_into CCO:B0067634 ! LEO1_HUMAN-Phosphoserine551 relationship: transforms_into CCO:B0067635 ! LEO1_HUMAN-Phosphoserine607 relationship: transforms_into CCO:B0067636 ! LEO1_HUMAN-Phosphoserine608 relationship: transforms_into CCO:B0067637 ! LEO1_HUMAN-Phosphoserine610 relationship: transforms_into CCO:B0067638 ! LEO1_HUMAN-Phosphoserine614 relationship: transforms_into CCO:B0067639 ! LEO1_HUMAN-Phosphothreonine629 relationship: transforms_into CCO:B0067640 ! LEO1_HUMAN-Phosphoserine630 relationship: transforms_into CCO:B0067641 ! LEO1_HUMAN-Phosphoserine658 [Term] id: CCO:B0057991 name: Q8WVF3_HUMAN def: "RAB28 protein" [UniProtKB:Q8WVF3] xref: EMBL:AAH18067.1 xref: UniProtKB:Q8WVF3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019584 ! RAB28_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0057992 name: CPLX3_HUMAN def: "Complexin-3 precursor" [UniProtKB:Q8WVH0] synonym: "Complexin III" EXACT [UniProtKB:Q8WVH0] synonym: "CPX III" EXACT [UniProtKB:Q8WVH0] xref: EMBL:AAH18026.1 xref: EMBL:AAP41127.1 xref: EMBL:BAB14805.1 xref: EMBL:BAB84922.1 xref: EMBL:BAE45711.1 xref: UniProtKB:Q8TEM6 xref: UniProtKB:Q8WVH0 xref: UniProtKB:Q9H818 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017439 ! CPLX3_human relationship: has_function CCO:F0001559 ! neurotransmitter transporter activity relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:P0002749 ! regulation of neurotransmitter secretion relationship: transforms_into CCO:B0064450 ! CPLX3_HUMAN-Cysteine methyl ester155 [Term] id: CCO:B0057993 name: PPR1C_HUMAN def: "Protein phosphatase 1 regulatory subunit 1C" [UniProtKB:Q8WVI7] xref: EMBL:AAH17943.1 xref: EMBL:AAM18054.1 xref: EMBL:CAI46089.1 xref: UniProtKB:Q5HYJ5 xref: UniProtKB:Q8TD54 xref: UniProtKB:Q8WVI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019484 ! PPP1R1C_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0057994 name: TWST2_HUMAN def: "Twist-related protein 2" [UniProtKB:Q8WVJ9] synonym: "Dermis-expressed protein 1" EXACT [UniProtKB:Q8WVJ9] synonym: "Dermo-1" EXACT [UniProtKB:Q8WVJ9] xref: EMBL:AAH17907.1 xref: EMBL:AAH33168.1 xref: EMBL:AAI03756.1 xref: UniProtKB:Q3SYL6 xref: UniProtKB:Q8WVJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020386 ! TWIST2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002482 ! negative regulation of osteoblast differentiation relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0057995 name: TFB1M_HUMAN def: "Dimethyladenosine transferase 1, mitochondrial precursor" [UniProtKB:Q8WVM0] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q8WVM0] synonym: "h-mtTFB" EXACT [UniProtKB:Q8WVM0] synonym: "h-mtTFB1" EXACT [UniProtKB:Q8WVM0] synonym: "hTFB1M" EXACT [UniProtKB:Q8WVM0] synonym: "Mitochondrial 12S rRNA dimethylase 1" EXACT [UniProtKB:Q8WVM0] synonym: "Mitochondrial transcription factor B1" EXACT [UniProtKB:Q8WVM0] synonym: "mtTFB1" EXACT [UniProtKB:Q8WVM0] synonym: "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1" EXACT [UniProtKB:Q8WVM0] xref: EMBL:AAD34070.1 xref: EMBL:AAH05183.1 xref: EMBL:AAH17788.1 xref: EMBL:CAI20506.1 xref: UniProtKB:Q05DR0 xref: UniProtKB:Q8WVM0 xref: UniProtKB:Q9Y384 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020246 ! TFB1M_human relationship: has_function CCO:F0000035 ! rRNA (adenine-N6,N6-)-dimethyltransferase activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0002014 ! rRNA methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057996 name: SCTM1_HUMAN def: "Secreted and transmembrane protein 1 precursor" [UniProtKB:Q8WVN6] synonym: "Protein K12" EXACT [UniProtKB:Q8WVN6] xref: EMBL:AAC52044.1 xref: EMBL:AAH17716.1 xref: UniProtKB:O00466 xref: UniProtKB:Q8WVN6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019853 ! SECTM1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0057997 name: CANT1_HUMAN def: "Soluble calcium-activated nucleotidase 1" [UniProtKB:Q8WVQ1] synonym: "Apyrase homolog" EXACT [UniProtKB:Q8WVQ1] synonym: "EC 3.6.1.6" EXACT [UniProtKB:Q8WVQ1] synonym: "Putative MAPK-activating protein PM09" EXACT [UniProtKB:Q8WVQ1] synonym: "Putative NF-kappa-B-activating protein 107" EXACT [UniProtKB:Q8WVQ1] synonym: "SCAN-1" EXACT [UniProtKB:Q8WVQ1] xref: EMBL:AAH05104.1 xref: EMBL:AAH17655.1 xref: EMBL:AAH65038.1 xref: EMBL:AAM94564.1 xref: EMBL:BAC11139.1 xref: EMBL:BAC77359.1 xref: EMBL:BAC77386.1 xref: EMBL:CAC85468.1 xref: UniProtKB:Q7Z2J7 xref: UniProtKB:Q8NG05 xref: UniProtKB:Q8NHP0 xref: UniProtKB:Q8WVQ1 xref: UniProtKB:Q9BSD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017223 ! CANT1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003166 ! pyrophosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003573 ! nucleoside-diphosphatase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0057998 name: Q8WVQ2_HUMAN def: "ZNF584 protein" [UniProtKB:Q8WVQ2] xref: EMBL:AAH17651.1 xref: UniProtKB:Q8WVQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020838 ! ZNF584_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0057999 name: FOG2_HUMAN def: "Zinc finger protein ZFPM2" [UniProtKB:Q8WW38] synonym: "FOG-2" EXACT [UniProtKB:Q8WW38] synonym: "Friend of GATA protein 2" EXACT [UniProtKB:Q8WW38] synonym: "hFOG-2" EXACT [UniProtKB:Q8WW38] synonym: "Zinc finger protein multitype 2" EXACT [UniProtKB:Q8WW38] xref: EMBL:AAD49558.1 xref: EMBL:AAH20928.1 xref: EMBL:AAI09223.1 xref: EMBL:CAB97539.1 xref: EMBL:CAB97541.1 xref: UniProtKB:Q32MA6 xref: UniProtKB:Q8WW38 xref: UniProtKB:Q9NPL7 xref: UniProtKB:Q9NPS4 xref: UniProtKB:Q9UNI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017819 ! ZFPM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018900 ! ubqln4-zfpm2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058000 name: APH1B_HUMAN def: "Gamma-secretase subunit APH-1B" [UniProtKB:Q8WW43] synonym: "APH-1b" EXACT [UniProtKB:Q8WW43] synonym: "Aph-1beta" EXACT [UniProtKB:Q8WW43] synonym: "Presenilin-stabilization factor-like" EXACT [UniProtKB:Q8WW43] xref: EMBL:AAH20905.1 xref: EMBL:AAN63817.1 xref: EMBL:AAQ89061.1 xref: EMBL:CAB66606.1 xref: UniProtKB:Q6UWQ1 xref: UniProtKB:Q8WW43 xref: UniProtKB:Q9H0S0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016988 ! APH1B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000978 ! transport vesicle relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0058001 name: Q8WW76_HUMAN def: "FGA protein" [UniProtKB:Q8WW76] xref: EMBL:AAH20764.1 xref: UniProtKB:Q8WW76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017805 ! FGA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058002 name: ITLN1_HUMAN def: "Intelectin-1 precursor" [UniProtKB:Q8WWA0] synonym: "Endothelial lectin HL-1" EXACT [UniProtKB:Q8WWA0] synonym: "Galactofuranose-binding lectin" EXACT [UniProtKB:Q8WWA0] synonym: "Intestinal lactoferrin receptor" EXACT [UniProtKB:Q8WWA0] synonym: "ITLN-1" EXACT [UniProtKB:Q8WWA0] synonym: "Omentin" EXACT [UniProtKB:Q8WWA0] xref: EMBL:AAH20664.1 xref: EMBL:AAL58073.1 xref: EMBL:AAM20741.1 xref: EMBL:AAO17800.1 xref: EMBL:AAO17801.1 xref: EMBL:AAQ88725.1 xref: EMBL:AAS49907.1 xref: EMBL:BAA90893.1 xref: EMBL:BAA96094.1 xref: EMBL:CAG33505.1 xref: UniProtKB:Q6YDJ3 xref: UniProtKB:Q8WWA0 xref: UniProtKB:Q9NP67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018346 ! ITLN1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001290 ! brush border membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058003 name: Q8WWE6_HUMAN def: "Zinc finger protein 226" [UniProtKB:Q8WWE6] synonym: "Zinc finger protein 226, isoform CRA_b" EXACT [UniProtKB:Q8WWE6] xref: EMBL:AAH17786.1 xref: EMBL:EAW57259.1 xref: UniProtKB:Q8WWE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020666 ! ZNF226_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058004 name: ASZ1_HUMAN def: "Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1" [UniProtKB:Q8WWH4] synonym: "Ankyrin-like protein 1" EXACT [UniProtKB:Q8WWH4] synonym: "Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein" EXACT [UniProtKB:Q8WWH4] xref: EMBL:AAI26187.1 xref: EMBL:AAI26189.1 xref: EMBL:AAL68815.1 xref: EMBL:BAC04167.1 xref: UniProtKB:A0AV27 xref: UniProtKB:Q8WWH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017088 ! ASZ1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_function CCO:F0008027 ! nitric-oxide synthase binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization [Term] id: CCO:B0058005 name: PHIP_HUMAN def: "PH-interacting protein" [UniProtKB:Q8WWQ0] synonym: "IRS-1 PH domain-binding protein" EXACT [UniProtKB:Q8WWQ0] synonym: "PHIP" EXACT [UniProtKB:Q8WWQ0] synonym: "WD repeat-containing protein 11" EXACT [UniProtKB:Q8WWQ0] xref: EMBL:AAG45145.1 xref: EMBL:AAH08909.2 xref: EMBL:AAH21905.1 xref: EMBL:AAH81569.1 xref: EMBL:BAB71353.1 xref: EMBL:BAC11417.1 xref: EMBL:CAC83118.1 xref: EMBL:CAH10776.1 xref: EMBL:CAH70884.1 xref: EMBL:CAI14406.1 xref: EMBL:EAW48718.1 xref: UniProtKB:Q05CQ9 xref: UniProtKB:Q5VVH4 xref: UniProtKB:Q66I29 xref: UniProtKB:Q69YV1 xref: UniProtKB:Q8NBZ5 xref: UniProtKB:Q8WWQ0 xref: UniProtKB:Q96H52 xref: UniProtKB:Q96ME2 xref: UniProtKB:Q9H261 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019382 ! PHIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0069266 ! PHIP_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0069267 ! PHIP_HUMAN-Phosphotyrosine140 relationship: transforms_into CCO:B0069268 ! PHIP_HUMAN-Phosphoserine683 relationship: transforms_into CCO:B0069269 ! PHIP_HUMAN-Phosphoserine911 relationship: transforms_into CCO:B0069270 ! PHIP_HUMAN-Phosphoserine1281 relationship: transforms_into CCO:B0069271 ! PHIP_HUMAN-Phosphoserine1283 relationship: transforms_into CCO:B0069272 ! PHIP_HUMAN-Phosphoserine1315 relationship: transforms_into CCO:B0069273 ! PHIP_HUMAN-Phosphoserine1405 relationship: transforms_into CCO:B0069274 ! PHIP_HUMAN-Phosphoserine1473 relationship: transforms_into CCO:B0069275 ! PHIP_HUMAN-Phosphoserine1479 relationship: transforms_into CCO:B0069276 ! PHIP_HUMAN-Phosphothreonine1480 relationship: transforms_into CCO:B0069277 ! PHIP_HUMAN-Phosphoserine1591 relationship: transforms_into CCO:B0069278 ! PHIP_HUMAN-Phosphoserine1592 relationship: transforms_into CCO:B0069279 ! PHIP_HUMAN-Phosphoserine1734 relationship: transforms_into CCO:B0069280 ! PHIP_HUMAN-Phosphoserine1762 relationship: transforms_into CCO:B0069281 ! PHIP_HUMAN-Phosphoserine1783 [Term] id: CCO:B0058006 name: ITLN2_HUMAN def: "Intelectin-2 precursor" [UniProtKB:Q8WWU7] synonym: "Endothelial lectin HL-2" EXACT [UniProtKB:Q8WWU7] xref: EMBL:AAL58074.1 xref: EMBL:AAQ89264.1 xref: UniProtKB:Q8WWU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018347 ! ITLN2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058007 name: ASB5_HUMAN def: "Ankyrin repeat and SOCS box protein 5" [UniProtKB:Q8WWX0] synonym: "ASB-5" EXACT [UniProtKB:Q8WWX0] xref: EMBL:AAH65710.1 xref: EMBL:AAL18248.1 xref: UniProtKB:Q8WWX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017069 ! ASB5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058008 name: MB3L1_HUMAN def: "Methyl-CpG-binding domain protein 3-like 1" [UniProtKB:Q8WWY6] synonym: "MBD3-like 1" EXACT [UniProtKB:Q8WWY6] xref: EMBL:AAI12059.1 xref: EMBL:AAI12065.1 xref: EMBL:AAK72591.1 xref: UniProtKB:Q2M291 xref: UniProtKB:Q8WWY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018576 ! MBD3L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058009 name: EDAD_HUMAN def: "Ectodysplasin-A receptor-associated adapter protein" [UniProtKB:Q8WWZ3] synonym: "Crinkled homolog" EXACT [UniProtKB:Q8WWZ3] synonym: "EDAR-associated death domain protein" EXACT [UniProtKB:Q8WWZ3] xref: EMBL:AAK40285.1 xref: EMBL:AAK40286.1 xref: EMBL:AAK40287.1 xref: EMBL:AAK40288.1 xref: EMBL:AAL60590.1 xref: EMBL:CAH70608.1 xref: EMBL:CAH70609.1 xref: EMBL:CAI22302.1 xref: EMBL:CAI22303.1 xref: UniProtKB:B1AL54 xref: UniProtKB:Q5VYJ7 xref: UniProtKB:Q8WWZ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017655 ! EDARADD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058010 name: IBPL1_HUMAN def: "Insulin-like growth factor-binding protein-like 1 precursor" [UniProtKB:Q8WX77] synonym: "IGFBP-related protein 10" EXACT [UniProtKB:Q8WX77] synonym: "IGFBP-rP4" EXACT [UniProtKB:Q8WX77] synonym: "Insulin-like growth factor-binding-related protein 4" EXACT [UniProtKB:Q8WX77] xref: EMBL:CAD13245.1 xref: EMBL:EAW58251.1 xref: UniProtKB:Q8WX77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018214 ! IGFBPL1_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0058011 name: NELFB_HUMAN def: "Negative elongation factor B" [UniProtKB:Q8WX92] synonym: "Cofactor of BRCA1" EXACT [UniProtKB:Q8WX92] synonym: "NELF-B" EXACT [UniProtKB:Q8WX92] xref: EMBL:AAH11892.1 xref: EMBL:AAL69965.1 xref: EMBL:BAA86496.1 xref: EMBL:BAB14157.1 xref: EMBL:CAB43381.3 xref: UniProtKB:Q8WX92 xref: UniProtKB:Q96EW5 xref: UniProtKB:Q9H9R4 xref: UniProtKB:Q9ULN8 xref: UniProtKB:Q9Y3W0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018750 ! COBRA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018448 ! rdbp-nelfb physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0068566 ! NELFB_HUMAN-Phosphoserine557 [Term] id: CCO:B0058012 name: Q8WX98_HUMAN def: "Cell recognition protein CASPR4" [UniProtKB:Q8WX98] xref: EMBL:AAL68839.1 xref: UniProtKB:Q8WX98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021246 ! CASPR4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058013 name: ZN606_HUMAN def: "Zinc finger protein 606" [UniProtKB:Q8WXB4] synonym: "Zinc finger protein 328" EXACT [UniProtKB:Q8WXB4] xref: EMBL:AAH37209.1 xref: EMBL:AAL58442.1 xref: EMBL:BAB47481.1 xref: UniProtKB:Q8NE04 xref: UniProtKB:Q8WXB4 xref: UniProtKB:Q96JH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020851 ! ZNF606_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058014 name: Q8WXB7_HUMAN def: "X-linked zinc finger protein" [UniProtKB:Q8WXB7] xref: EMBL:AAL51084.1 xref: UniProtKB:Q8WXB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020598 ! ZFX_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058015 name: CSKI1_HUMAN def: "Caskin-1" [UniProtKB:Q8WXD9] synonym: "CASK-interacting protein 1" EXACT [UniProtKB:Q8WXD9] xref: EMBL:AAL49758.1 xref: EMBL:BAA92544.1 xref: UniProtKB:Q8WXD9 xref: UniProtKB:Q9P2P0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017479 ! CASKIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006665 ! npm_alk-cdc14 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064557 ! CSKI1_HUMAN-Phosphotyrosine253 relationship: transforms_into CCO:B0064558 ! CSKI1_HUMAN-Phosphoserine646 relationship: transforms_into CCO:B0064559 ! CSKI1_HUMAN-Phosphothreonine775 relationship: transforms_into CCO:B0064560 ! CSKI1_HUMAN-Phosphoserine787 relationship: transforms_into CCO:B0064561 ! CSKI1_HUMAN-Phosphothreonine1065 relationship: transforms_into CCO:B0064562 ! CSKI1_HUMAN-Phosphoserine1067 relationship: transforms_into CCO:B0064563 ! CSKI1_HUMAN-Phosphoserine1257 relationship: transforms_into CCO:B0064564 ! CSKI1_HUMAN-Phosphoserine1364 [Term] id: CCO:B0058016 name: STON2_HUMAN def: "Stonin-2" [UniProtKB:Q8WXE9] synonym: "Stoned B" EXACT [UniProtKB:Q8WXE9] xref: EMBL:AAH69389.1 xref: EMBL:AAI17494.1 xref: EMBL:AAK57558.1 xref: EMBL:AAK76362.1 xref: EMBL:AAL47008.1 xref: UniProtKB:Q17R24 xref: UniProtKB:Q6NT47 xref: UniProtKB:Q8WXE9 xref: UniProtKB:Q96RI7 xref: UniProtKB:Q96RU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020073 ! STON2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: participates_in CCO:I0016276 ! stn2-syt1-1 colocalization relationship: participates_in CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:B0058017 name: PSPC1_HUMAN def: "Paraspeckle component 1" [UniProtKB:Q8WXF1] synonym: "Paraspeckle protein 1" EXACT [UniProtKB:Q8WXF1] xref: EMBL:AAH14184.2 xref: EMBL:AAL59601.1 xref: EMBL:AAL59602.1 xref: EMBL:BAA91924.1 xref: EMBL:CAD39162.1 xref: EMBL:CAG33553.1 xref: EMBL:CAI41004.1 xref: EMBL:CAI41005.1 xref: EMBL:EAX08232.1 xref: UniProtKB:Q5JTQ3 xref: UniProtKB:Q8NCZ9 xref: UniProtKB:Q8WXE8 xref: UniProtKB:Q8WXF1 xref: UniProtKB:Q9NV36 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019532 ! PSPC1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069580 ! PSPC1_HUMAN-Phosphoserine509 [Term] id: CCO:B0058018 name: GPR98_HUMAN def: "G-protein coupled receptor 98 precursor" [UniProtKB:Q8WXG9] synonym: "Monogenic audiogenic seizure susceptibility protein 1 homolog" EXACT [UniProtKB:Q8WXG9] synonym: "Usher syndrome type-2C protein" EXACT [UniProtKB:Q8WXG9] synonym: "Very large G-protein coupled receptor 1" EXACT [UniProtKB:Q8WXG9] xref: EMBL:AAD55586.1 xref: EMBL:AAL30811.1 xref: EMBL:BAA31661.2 xref: EMBL:BAB85529.1 xref: EMBL:CAB66476.2 xref: UniProtKB:O75171 xref: UniProtKB:Q8TF58 xref: UniProtKB:Q8WXG9 xref: UniProtKB:Q9H0X5 xref: UniProtKB:Q9UL61 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018043 ! GPR98_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0002849 ! maintenance of organ identity [Term] id: CCO:B0058019 name: ASB11_HUMAN def: "Ankyrin repeat and SOCS box protein 11" [UniProtKB:Q8WXH4] synonym: "ASB-11" EXACT [UniProtKB:Q8WXH4] xref: EMBL:AAH69340.1 xref: EMBL:AAI03875.1 xref: EMBL:AAI03876.1 xref: EMBL:AAL60519.1 xref: UniProtKB:Q3SYC4 xref: UniProtKB:Q8WXH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017058 ! ASB11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058020 name: SOCS4_HUMAN def: "Suppressor of cytokine signaling 4" [UniProtKB:Q8WXH5] synonym: "SOCS-4" EXACT [UniProtKB:Q8WXH5] synonym: "SOCS-7" EXACT [UniProtKB:Q8WXH5] synonym: "Suppressor of cytokine signaling 7" EXACT [UniProtKB:Q8WXH5] xref: EMBL:AAH60790.1 xref: EMBL:AAL60517.1 xref: UniProtKB:Q8WXH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019974 ! SOCS4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0058021 name: RB40A_HUMAN def: "Ras-related protein Rab-40A" [UniProtKB:Q8WXH6] synonym: "Protein Rar-2" EXACT [UniProtKB:Q8WXH6] synonym: "SOCS box-containing protein RAR2A" EXACT [UniProtKB:Q8WXH6] xref: EMBL:AAH74854.1 xref: EMBL:AAH74855.1 xref: EMBL:AAI13502.1 xref: EMBL:AAI17233.1 xref: EMBL:AAL60514.1 xref: EMBL:AAL75949.1 xref: EMBL:BAF02899.1 xref: EMBL:CAI41993.1 xref: UniProtKB:O00407 xref: UniProtKB:Q17RQ5 xref: UniProtKB:Q6DK06 xref: UniProtKB:Q8TF06 xref: UniProtKB:Q8WXH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019640 ! RAB40A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058022 name: CNKR2_HUMAN def: "Connector enhancer of kinase suppressor of ras 2" [UniProtKB:Q8WXI2] synonym: "CNK2" EXACT [UniProtKB:Q8WXI2] synonym: "Connector enhancer of KSR2" EXACT [UniProtKB:Q8WXI2] xref: EMBL:AAI26122.1 xref: EMBL:AAL60502.1 xref: EMBL:AAL60503.1 xref: EMBL:BAA74925.2 xref: EMBL:CAH70864.1 xref: EMBL:CAI39867.1 xref: EMBL:CAI40766.1 xref: UniProtKB:O94976 xref: UniProtKB:Q5JPK4 xref: UniProtKB:Q8WXI1 xref: UniProtKB:Q8WXI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017406 ! CNKSR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017426 ! tnik-cnksr2 physical interaction relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0064419 ! CNKR2_HUMAN-Phosphoserine248 relationship: transforms_into CCO:B0064420 ! CNKR2_HUMAN-Phosphoserine325 relationship: transforms_into CCO:B0064421 ! CNKR2_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0064422 ! CNKR2_HUMAN-Phosphoserine467 relationship: transforms_into CCO:B0064423 ! CNKR2_HUMAN-Phosphothreonine846 relationship: transforms_into CCO:B0064424 ! CNKR2_HUMAN-Phosphoserine908 [Term] id: CCO:B0058023 name: ASB10_HUMAN def: "Ankyrin repeat and SOCS box protein 10" [UniProtKB:Q8WXI3] synonym: "ASB-10" EXACT [UniProtKB:Q8WXI3] xref: EMBL:AAI26352.1 xref: EMBL:AAL59159.1 xref: UniProtKB:A0AVH0 xref: UniProtKB:Q8WXI3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017057 ! ASB10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058024 name: ACO11_HUMAN def: "Acyl-coenzyme A thioesterase 11" [UniProtKB:Q8WXI4] synonym: "Acyl-CoA thioester hydrolase 11" EXACT [UniProtKB:Q8WXI4] synonym: "Acyl-CoA thioesterase 11" EXACT [UniProtKB:Q8WXI4] synonym: "Adipose-associated thioesterase" EXACT [UniProtKB:Q8WXI4] synonym: "BFIT" EXACT [UniProtKB:Q8WXI4] synonym: "Brown fat-inducible thioesterase" EXACT [UniProtKB:Q8WXI4] synonym: "EC 3.1.2.-" EXACT [UniProtKB:Q8WXI4] xref: EMBL:AAH01517.1 xref: EMBL:AAL40937.1 xref: EMBL:AAL40938.1 xref: EMBL:BAA31682.1 xref: EMBL:BAB14734.1 xref: UniProtKB:O75187 xref: UniProtKB:Q8WXI4 xref: UniProtKB:Q96DI1 xref: UniProtKB:Q9H883 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016903 ! ACOT11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0065388 ! ACO11_HUMAN-Phosphoserine367 [Term] id: CCO:B0058025 name: Q8WXJ7_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:Q8WXJ7] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q8WXJ7] xref: EMBL:AAL67965.1 xref: EMBL:CAH71816.1 xref: EMBL:CAH72195.1 xref: EMBL:CAH72316.1 xref: EMBL:EAW62688.1 xref: UniProtKB:Q8WXJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018886 ! NTRK2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0058026 name: ASB17_HUMAN def: "Ankyrin repeat and SOCS box protein 17" [UniProtKB:Q8WXJ9] synonym: "ASB-17" EXACT [UniProtKB:Q8WXJ9] xref: EMBL:AAH36573.1 xref: EMBL:AAL57354.1 xref: EMBL:AAN85310.1 xref: EMBL:BAC05350.1 xref: UniProtKB:Q8N0X5 xref: UniProtKB:Q8WXJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017063 ! ASB17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058027 name: ASB15_HUMAN def: "Ankyrin repeat and SOCS box protein 15" [UniProtKB:Q8WXK1] synonym: "ASB-15" EXACT [UniProtKB:Q8WXK1] xref: EMBL:AAL57352.1 xref: EMBL:BAC86146.1 xref: UniProtKB:Q8WXK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017061 ! ASB15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058028 name: DYH12_HUMAN def: "Dynein heavy chain 12, axonemal" [UniProtKB:Q8WXK2] synonym: "Ankyrin repeat and SOCS box protein 14" EXACT [UniProtKB:Q8WXK2] synonym: "ASB-14" EXACT [UniProtKB:Q8WXK2] synonym: "Axonemal beta dynein heavy chain 12" EXACT [UniProtKB:Q8WXK2] synonym: "Ciliary dynein heavy chain 12" EXACT [UniProtKB:Q8WXK2] xref: EMBL:AAB09729.1 xref: EMBL:AAL57351.1 xref: UniProtKB:Q8WXK2 xref: UniProtKB:Q92816 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017647 ! DNAH12_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000995 ! dynein complex relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058029 name: ASB13_HUMAN def: "Ankyrin repeat and SOCS box protein 13" [UniProtKB:Q8WXK3] synonym: "ASB-13" EXACT [UniProtKB:Q8WXK3] xref: EMBL:AAH12056.1 xref: EMBL:AAL57350.1 xref: EMBL:BAB14456.1 xref: EMBL:CAG33583.1 xref: EMBL:CAH72614.1 xref: UniProtKB:Q8WXK3 xref: UniProtKB:Q96EP7 xref: UniProtKB:Q9H8Z1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017060 ! ASB13_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015339 ! asb13-hif1an physical interaction relationship: participates_in CCO:I0018841 ! asb13-mark3-1 physical interaction relationship: participates_in CCO:I0020294 ! dnm1-asb13 physical interaction relationship: participates_in CCO:I0020387 ! nudt3-asb13 physical interaction relationship: participates_in CCO:I0020589 ! mark3-asb13 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058030 name: ASB12_HUMAN def: "Ankyrin repeat and SOCS box protein 12" [UniProtKB:Q8WXK4] synonym: "ASB-12" EXACT [UniProtKB:Q8WXK4] xref: EMBL:AAH69436.1 xref: EMBL:AAH69555.1 xref: EMBL:AAH93883.1 xref: EMBL:AAI04947.1 xref: EMBL:AAL57349.1 xref: EMBL:CAI39932.1 xref: UniProtKB:Q2M3D5 xref: UniProtKB:Q52LK4 xref: UniProtKB:Q6ISF9 xref: UniProtKB:Q8WXK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017059 ! ASB12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058031 name: Q8WXL5_HUMAN def: "Dopamine receptor D4" [UniProtKB:Q8WXL5] xref: EMBL:AAL35213.1 xref: UniProtKB:Q8WXL5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017620 ! DRD4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058032 name: Q8WXL8_HUMAN def: "Dopamine receptor D4" [UniProtKB:Q8WXL8] xref: EMBL:AAL35210.1 xref: UniProtKB:Q8WXL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017620 ! DRD4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058033 name: Q8WXN2_HUMAN def: "Dopamine receptor D4" [UniProtKB:Q8WXN2] xref: EMBL:AAL35190.1 xref: UniProtKB:Q8WXN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017620 ! DRD4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001294 ! dopamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058034 name: Q8WXV1_HUMAN def: "SPPR-2" [UniProtKB:Q8WXV1] xref: EMBL:AAL57043.1 xref: UniProtKB:Q8WXV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058035 name: Q8WXV2_HUMAN def: "SPPR-1" [UniProtKB:Q8WXV2] xref: EMBL:AAL57042.1 xref: UniProtKB:Q8WXV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058036 name: Q8WXZ9_HUMAN def: "Histamine H3 receptor isoform 4" [UniProtKB:Q8WXZ9] xref: EMBL:AAL71914.1 xref: UniProtKB:Q8WXZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018160 ! HRH3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058037 name: Q8WY32_HUMAN def: "TAR RNA-binding protein TRBP1" [UniProtKB:Q8WY32] xref: EMBL:AAL55730.1 xref: UniProtKB:Q8WY32 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020347 ! TARBP2_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0002738 ! regulation of viral transcription [Term] id: CCO:B0058038 name: BBX_HUMAN def: "HMG box transcription factor BBX" [UniProtKB:Q8WY36] synonym: "Bobby sox homolog" EXACT [UniProtKB:Q8WY36] synonym: "HMG box-containing protein 2" EXACT [UniProtKB:Q8WY36] xref: EMBL:AAH12837.2 xref: EMBL:AAI10904.1 xref: EMBL:AAL58870.1 xref: EMBL:AAL58871.1 xref: EMBL:AAL68984.1 xref: EMBL:AAL68985.1 xref: EMBL:CAB66703.1 xref: EMBL:CAD38977.1 xref: UniProtKB:Q2TAJ1 xref: UniProtKB:Q7L3J8 xref: UniProtKB:Q7LBY8 xref: UniProtKB:Q8NDB0 xref: UniProtKB:Q8WY35 xref: UniProtKB:Q8WY36 xref: UniProtKB:Q9H0J6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017135 ! BBX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063781 ! BBX_HUMAN-Phosphoserine479 relationship: transforms_into CCO:B0063782 ! BBX_HUMAN-Phosphoserine485 relationship: transforms_into CCO:B0063783 ! BBX_HUMAN-Phosphothreonine809 relationship: transforms_into CCO:B0063784 ! BBX_HUMAN-Phosphoserine822 [Term] id: CCO:B0058039 name: NANO1_HUMAN def: "Nanos homolog 1" [UniProtKB:Q8WY41] synonym: "EC_Rep1a" EXACT [UniProtKB:Q8WY41] synonym: "NOS-1" EXACT [UniProtKB:Q8WY41] xref: EMBL:AAL36982.2 xref: EMBL:AAQ04765.1 xref: EMBL:CAI14718.1 xref: UniProtKB:Q8WY41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018715 ! NANOS1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0058040 name: Q8WY67_HUMAN def: "PP4748" [UniProtKB:Q8WY67] synonym: "RAB24, member RAS oncogene family, isoform CRA_d" EXACT [UniProtKB:Q8WY67] xref: EMBL:AAG23786.1 xref: EMBL:EAW85027.1 xref: UniProtKB:Q8WY67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019581 ! RAB24_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058041 name: BMAL2_HUMAN def: "Aryl hydrocarbon receptor nuclear translocator-like protein 2" [UniProtKB:Q8WYA1] synonym: "Basic-helix-loop-helix-PAS protein MOP9" EXACT [UniProtKB:Q8WYA1] synonym: "Brain and muscle ARNT-like 2" EXACT [UniProtKB:Q8WYA1] synonym: "CLIF" EXACT [UniProtKB:Q8WYA1] synonym: "CYCLE-like factor" EXACT [UniProtKB:Q8WYA1] synonym: "Member of PAS protein 9" EXACT [UniProtKB:Q8WYA1] xref: EMBL:AAF71306.1 xref: EMBL:AAF71307.1 xref: EMBL:AAG34652.1 xref: EMBL:AAH00172.3 xref: EMBL:AAI25062.1 xref: EMBL:AAI25063.1 xref: EMBL:AAL50339.1 xref: EMBL:AAL50340.1 xref: EMBL:AAL50341.1 xref: EMBL:AAL50342.1 xref: EMBL:BAB01485.1 xref: UniProtKB:Q8WYA1 xref: UniProtKB:Q8WYA2 xref: UniProtKB:Q8WYA3 xref: UniProtKB:Q8WYA4 xref: UniProtKB:Q96J63 xref: UniProtKB:Q9H2M4 xref: UniProtKB:Q9NS70 xref: UniProtKB:Q9NYQ4 xref: UniProtKB:Q9NYQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017166 ! ARNTL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058042 name: CNTP5_HUMAN def: "Contactin-associated protein-like 5 precursor" [UniProtKB:Q8WYK1] synonym: "Cell recognition molecule Caspr5" EXACT [UniProtKB:Q8WYK1] xref: EMBL:AAX81997.1 xref: EMBL:AAX88894.1 xref: EMBL:AAX88904.1 xref: EMBL:AAY14716.1 xref: EMBL:AAY15042.1 xref: EMBL:AAY24250.1 xref: EMBL:BAB71205.1 xref: EMBL:BAB83897.1 xref: EMBL:EAW95266.1 xref: UniProtKB:Q4ZFW2 xref: UniProtKB:Q4ZG21 xref: UniProtKB:Q53R09 xref: UniProtKB:Q53RX1 xref: UniProtKB:Q53SG3 xref: UniProtKB:Q584P3 xref: UniProtKB:Q8WYK1 xref: UniProtKB:Q96MS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017420 ! CNTNAP5_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058043 name: JDP2_HUMAN def: "Jun dimerization protein 2" [UniProtKB:Q8WYK2] xref: EMBL:AAC98313.1 xref: EMBL:AAF21148.1 xref: EMBL:AAH51303.1 xref: EMBL:BAB83896.1 xref: EMBL:EAW81231.1 xref: UniProtKB:O95430 xref: UniProtKB:Q8WYK2 xref: UniProtKB:Q9UIE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018358 ! JDP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067197 ! JDP2_HUMAN-Phosphothreonine148 [Term] id: CCO:B0058044 name: Q8WYK7_HUMAN def: "WNT1 inducible signaling pathway protein 3 variant" [UniProtKB:Q8WYK7] xref: EMBL:BAB78569.1 xref: UniProtKB:Q8WYK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021247 ! wisp3 varinat_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0058045 name: Q8WYM6_HUMAN def: "ATF3deltaZip2" [UniProtKB:Q8WYM6] synonym: "Activating transcription factor 3" EXACT [UniProtKB:Q8WYM6] synonym: "Activating transcription factor 3 delta Zip2" EXACT [UniProtKB:Q8WYM6] synonym: "Activating transcription factor 3, isoform CRA_d" EXACT [UniProtKB:Q8WYM6] xref: EMBL:BAB84092.1 xref: EMBL:BAC00495.1 xref: EMBL:BAC00496.1 xref: EMBL:CAH72653.1 xref: EMBL:EAW93386.1 xref: UniProtKB:Q8WYM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004114 ! ATF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058046 name: CSRN3_HUMAN def: "Cysteine/serine-rich nuclear protein 3" [UniProtKB:Q8WYN3] synonym: "CSRNP-3" EXACT [UniProtKB:Q8WYN3] synonym: "Protein FAM130A2" EXACT [UniProtKB:Q8WYN3] synonym: "TAIP-2" EXACT [UniProtKB:Q8WYN3] synonym: "TGF-beta-induced apoptosis protein 2" EXACT [UniProtKB:Q8WYN3] xref: EMBL:AAY24139.1 xref: EMBL:BAB13890.1 xref: EMBL:BAB79449.1 xref: EMBL:BAC86454.1 xref: UniProtKB:Q53SG0 xref: UniProtKB:Q6ZTX3 xref: UniProtKB:Q8WYN3 xref: UniProtKB:Q9HAF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017485 ! CSRNP3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058047 name: RIN2_HUMAN def: "Ras and Rab interactor 2" [UniProtKB:Q8WYP3] synonym: "Ras association domain family 4" EXACT [UniProtKB:Q8WYP3] synonym: "Ras inhibitor JC265" EXACT [UniProtKB:Q8WYP3] synonym: "Ras interaction/interference protein 2" EXACT [UniProtKB:Q8WYP3] xref: EMBL:AAA36553.1 xref: EMBL:BAB84317.1 xref: EMBL:CAB66858.1 xref: EMBL:CAI19340.1 xref: EMBL:CAI23572.1 xref: UniProtKB:Q00425 xref: UniProtKB:Q5TFT8 xref: UniProtKB:Q8WYP3 xref: UniProtKB:Q9BQL3 xref: UniProtKB:Q9H071 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019743 ! RIN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0070053 ! RIN2_HUMAN-Phosphoserine501 relationship: transforms_into CCO:B0070054 ! RIN2_HUMAN-Phosphothreonine509 [Term] id: CCO:B0058048 name: DGCR8_HUMAN def: "Protein DGCR8" [UniProtKB:Q8WYQ5] synonym: "DiGeorge syndrome critical region 8" EXACT [UniProtKB:Q8WYQ5] xref: EMBL:AAF82263.1 xref: EMBL:AAH09323.2 xref: EMBL:AAH09984.1 xref: EMBL:AAH78147.1 xref: EMBL:AAO86726.1 xref: EMBL:BAB15165.1 xref: EMBL:BAB15238.1 xref: EMBL:BAB83032.1 xref: EMBL:CAE46205.2 xref: EMBL:CAG30242.1 xref: UniProtKB:Q6DCB2 xref: UniProtKB:Q6MZE9 xref: UniProtKB:Q6Y2L0 xref: UniProtKB:Q8WYQ5 xref: UniProtKB:Q96G39 xref: UniProtKB:Q96GP8 xref: UniProtKB:Q9H6L8 xref: UniProtKB:Q9H6T7 xref: UniProtKB:Q9NRW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017563 ! DGCR8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017369 ! rnase3l-dgcr8-1 physical interaction relationship: participates_in CCO:I0018312 ! rnase3l-dgcr8-2 physical interaction relationship: participates_in CCO:I0018313 ! rnase3l-dgcr8-3 physical interaction relationship: participates_in CCO:I0018796 ! rnase3l-dgcr8-4 physical interaction relationship: participates_in CCO:P0001365 ! primary microRNA processing relationship: transforms_into CCO:B0064745 ! DGCR8_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0064746 ! DGCR8_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0064747 ! DGCR8_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0064748 ! DGCR8_HUMAN-Phosphoserine271 relationship: transforms_into CCO:B0064749 ! DGCR8_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0064750 ! DGCR8_HUMAN-Phosphoserine377 [Term] id: CCO:B0058049 name: KCD13_HUMAN def: "BTB/POZ domain-containing protein KCTD13" [UniProtKB:Q8WZ19] synonym: "Polymerase delta-interacting protein 1" EXACT [UniProtKB:Q8WZ19] synonym: "TNFAIP1-like protein" EXACT [UniProtKB:Q8WZ19] xref: EMBL:AAH36228.1 xref: EMBL:AAK27301.1 xref: EMBL:AAL14962.2 xref: EMBL:AAL55757.1 xref: UniProtKB:Q8WZ19 xref: UniProtKB:Q96P93 xref: UniProtKB:Q96SA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018385 ! KCTD13_human relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015050 ! armc7-kctd13 physical interaction relationship: participates_in CCO:I0015170 ! c6orf55-kctd13 physical interaction relationship: participates_in CCO:I0015441 ! kctd13-zmynd19 physical interaction relationship: participates_in CCO:I0015449 ! kctd13-lnx physical interaction relationship: participates_in CCO:I0015613 ! kctd13-myst2 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058050 name: CTTB2_HUMAN def: "Cortactin-binding protein 2" [UniProtKB:Q8WZ74] synonym: "CortBP2" EXACT [UniProtKB:Q8WZ74] xref: EMBL:AAC04501.2 xref: EMBL:AAI06001.1 xref: EMBL:AAL32176.1 xref: EMBL:ABC79049.1 xref: EMBL:ABC79051.1 xref: EMBL:ABC79053.1 xref: EMBL:ABC79055.1 xref: EMBL:ABC87052.1 xref: EMBL:ABC87056.1 xref: EMBL:ABC87058.1 xref: EMBL:ABC87060.1 xref: EMBL:ABC87062.1 xref: EMBL:ABC87066.1 xref: EMBL:BAB21849.1 xref: UniProtKB:O43389 xref: UniProtKB:Q7LG11 xref: UniProtKB:Q8WZ74 xref: UniProtKB:Q9C0A5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017493 ! CTTNBP2_human relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_function CCO:F0008027 ! nitric-oxide synthase binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000505 ! negative regulation of endothelial cell proliferation relationship: participates_in CCO:P0001386 ! positive regulation of microtubule polymerization [Term] id: CCO:B0058051 name: ROBO4_HUMAN def: "Roundabout homolog 4 precursor" [UniProtKB:Q8WZ75] synonym: "Magic roundabout" EXACT [UniProtKB:Q8WZ75] xref: EMBL:AAH39602.1 xref: EMBL:AAH64643.1 xref: EMBL:AAI11563.1 xref: EMBL:AAI11749.1 xref: EMBL:AAL31867.1 xref: EMBL:AAQ88450.1 xref: EMBL:BAA91382.1 xref: EMBL:BAB15082.1 xref: EMBL:BAB55411.1 xref: EMBL:BAB84989.1 xref: UniProtKB:Q14DU7 xref: UniProtKB:Q8TEG1 xref: UniProtKB:Q8WZ75 xref: UniProtKB:Q96JV6 xref: UniProtKB:Q9H718 xref: UniProtKB:Q9NWJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019764 ! ROBO4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001257 ! regulation of cell migration [Term] id: CCO:B0058052 name: OR8D1_HUMAN def: "Olfactory receptor 8D1" [UniProtKB:Q8WZ84] synonym: "Olfactory receptor OR11-301" EXACT [UniProtKB:Q8WZ84] synonym: "Olfactory receptor-like protein JCG9" EXACT [UniProtKB:Q8WZ84] synonym: "OST004" EXACT [UniProtKB:Q8WZ84] xref: EMBL:AAL32998.1 xref: EMBL:DAA04899.1 xref: UniProtKB:Q6IEW1 xref: UniProtKB:Q8WZ84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019227 ! OR8D1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058053 name: OR5P2_HUMAN def: "Olfactory receptor 5P2" [UniProtKB:Q8WZ92] synonym: "Olfactory receptor-like protein JCG3" EXACT [UniProtKB:Q8WZ92] xref: EMBL:AAI01711.1 xref: EMBL:AAI13558.1 xref: EMBL:AAL32992.1 xref: EMBL:BAC05987.1 xref: UniProtKB:Q3MIS8 xref: UniProtKB:Q8WZ92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019192 ! OR5P2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058054 name: OR5P3_HUMAN def: "Olfactory receptor 5P3" [UniProtKB:Q8WZ94] synonym: "Olfactory receptor-like protein JCG1" EXACT [UniProtKB:Q8WZ94] xref: EMBL:AAL32991.1 xref: EMBL:BAC05990.1 xref: UniProtKB:Q8NGM2 xref: UniProtKB:Q8WZ94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019193 ! OR5P3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058055 name: RPGF4_HUMAN def: "Rap guanine nucleotide exchange factor 4" [UniProtKB:Q8WZA2] synonym: "cAMP-GEFII" EXACT [UniProtKB:Q8WZA2] synonym: "cAMP-regulated guanine nucleotide exchange factor II" EXACT [UniProtKB:Q8WZA2] synonym: "Epac 2" EXACT [UniProtKB:Q8WZA2] synonym: "Exchange factor directly activated by cAMP 2" EXACT [UniProtKB:Q8WZA2] xref: EMBL:AAD03422.1 xref: EMBL:AAH24004.1 xref: EMBL:AAH40183.1 xref: EMBL:BAB72179.1 xref: UniProtKB:O95636 xref: UniProtKB:Q8IXK6 xref: UniProtKB:Q8TAA4 xref: UniProtKB:Q8WZA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019787 ! RAPGEF4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0004464 ! cAMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0019005 ! atxn1-rapgef4 physical interaction relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0070168 ! RPGF4_HUMAN-Phosphotyrosine681 [Term] id: CCO:B0058056 name: OR1E3_HUMAN def: "Olfactory receptor 1E3" [UniProtKB:Q8WZA6] synonym: "Olfactory receptor 17-210" EXACT [UniProtKB:Q8WZA6] synonym: "Olfactory receptor OR17-7" EXACT [UniProtKB:Q8WZA6] synonym: "OR17-210" EXACT [UniProtKB:Q8WZA6] xref: EMBL:AAA18353.1 xref: UniProtKB:Q8WZA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019063 ! OR1E3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058057 name: AQP3_HUMAN def: "Aquaporin-3" [UniProtKB:Q92482] synonym: "AQP-3" EXACT [UniProtKB:Q92482] xref: EMBL:AAH13566.1 xref: EMBL:AAP35863.1 xref: EMBL:AAY68214.1 xref: EMBL:BAA19237.1 xref: EMBL:CAD38526.1 xref: EMBL:CAG46788.1 xref: EMBL:CAI13311.1 xref: UniProtKB:O00108 xref: UniProtKB:Q6FGW6 xref: UniProtKB:Q92482 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016997 ! AQP3_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0002717 ! water channel activity relationship: has_function CCO:F0002720 ! glycerol channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: participates_in CCO:P0002430 ! regulation of keratinocyte differentiation [Term] id: CCO:B0058058 name: DDX1_HUMAN def: "ATP-dependent RNA helicase DDX1" [UniProtKB:Q92499] synonym: "DBP-RB" EXACT [UniProtKB:Q92499] synonym: "DEAD box protein 1" EXACT [UniProtKB:Q92499] synonym: "DEAD box protein retinoblastoma" EXACT [UniProtKB:Q92499] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q92499] xref: EMBL:AAH12132.1 xref: EMBL:AAH53673.1 xref: EMBL:CAA49992.1 xref: UniProtKB:Q92499 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017545 ! DDX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016888 ! relb-ddx1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0064692 ! DDX1_HUMAN-Phosphothreonine80 relationship: transforms_into CCO:B0064693 ! DDX1_HUMAN-Phosphothreonine83 relationship: transforms_into CCO:B0064694 ! DDX1_HUMAN-Phosphotyrosine628 [Term] id: CCO:B0058059 name: CPT1B_HUMAN def: "Carnitine O-palmitoyltransferase 1, muscle isoform" [UniProtKB:Q92523] synonym: "Carnitine O-palmitoyltransferase I, muscle isoform" EXACT [UniProtKB:Q92523] synonym: "Carnitine palmitoyltransferase 1B" EXACT [UniProtKB:Q92523] synonym: "Carnitine palmitoyltransferase I-like protein" EXACT [UniProtKB:Q92523] synonym: "CPT I" EXACT [UniProtKB:Q92523] synonym: "CPT1-M" EXACT [UniProtKB:Q92523] synonym: "CPTI-M" EXACT [UniProtKB:Q92523] synonym: "EC 2.3.1.21" EXACT [UniProtKB:Q92523] xref: EMBL:AAB03343.1 xref: EMBL:AAB40651.1 xref: EMBL:AAC51122.1 xref: EMBL:BAA13461.1 xref: EMBL:BAA21492.1 xref: EMBL:BAB33340.1 xref: EMBL:CAA69938.1 xref: EMBL:CAA69939.1 xref: UniProtKB:Q13389 xref: UniProtKB:Q92523 xref: UniProtKB:Q99655 xref: UniProtKB:Q9BY90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017443 ! CPT1B_human relationship: has_function CCO:F0000568 ! carnitine O-palmitoyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: participates_in CCO:P0002686 ! regulation of fatty acid oxidation [Term] id: CCO:B0058060 name: SHC3_HUMAN def: "SHC-transforming protein 3" [UniProtKB:Q92529] synonym: "N-Shc" EXACT [UniProtKB:Q92529] synonym: "Neuronal Shc" EXACT [UniProtKB:Q92529] synonym: "Protein Rai" EXACT [UniProtKB:Q92529] synonym: "SH2 domain protein C3" EXACT [UniProtKB:Q92529] synonym: "Src homology 2 domain-containing-transforming protein C3" EXACT [UniProtKB:Q92529] xref: EMBL:AAH26314.1 xref: EMBL:BAA12322.1 xref: EMBL:BAA12323.1 xref: UniProtKB:Q8TAP2 xref: UniProtKB:Q92529 xref: UniProtKB:Q9UCX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019894 ! SHC3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:B0058061 name: SMG7_HUMAN def: "Protein SMG7" [UniProtKB:Q92540] synonym: "EST1-like protein C" EXACT [UniProtKB:Q92540] synonym: "SMG-7 homolog" EXACT [UniProtKB:Q92540] xref: EMBL:AAH36381.1 xref: EMBL:AAH52565.1 xref: EMBL:BAA13381.2 xref: EMBL:BAC53621.1 xref: EMBL:BAC53622.1 xref: EMBL:CAI16627.1 xref: EMBL:CAI19486.1 xref: UniProtKB:Q5T1Q0 xref: UniProtKB:Q6PIE0 xref: UniProtKB:Q7Z7H9 xref: UniProtKB:Q8IXC1 xref: UniProtKB:Q8IXC2 xref: UniProtKB:Q92540 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019952 ! SMG7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020310 ! fgfr3-c1orf16 physical interaction relationship: participates_in CCO:P0002016 ! regulation of dephosphorylation relationship: transforms_into CCO:B0070645 ! SMG7_HUMAN-Phosphoserine781 relationship: transforms_into CCO:B0070646 ! SMG7_HUMAN-Phosphoserine897 [Term] id: CCO:B0058062 name: NICA_HUMAN def: "Nicastrin precursor" [UniProtKB:Q92542] xref: EMBL:AAG11412.1 xref: EMBL:AAH47621.1 xref: EMBL:AAQ89478.1 xref: EMBL:BAA13383.1 xref: UniProtKB:Q86VV5 xref: UniProtKB:Q92542 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018788 ! NCSTN_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0016196 ! tmed10-psen1-4 physical interaction relationship: participates_in CCO:I0017774 ! tmed10-ncstn-2 physical interaction relationship: participates_in CCO:I0018565 ! tmed10-psen1-5 physical interaction relationship: participates_in CCO:I0018697 ! tmed10-psen1 physical interaction relationship: participates_in CCO:I0018885 ! tmed10-ncstn physical interaction relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000755 ! Notch receptor processing [Term] id: CCO:B0058063 name: BAP1_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase BAP1" [UniProtKB:Q92560] synonym: "BRCA1-associated protein 1" EXACT [UniProtKB:Q92560] synonym: "Cerebral protein 6" EXACT [UniProtKB:Q92560] synonym: "EC 3.4.19.12" EXACT [UniProtKB:Q92560] xref: EMBL:AAC15970.1 xref: EMBL:AAH01596.1 xref: EMBL:AAN05092.1 xref: EMBL:BAA13401.2 xref: EMBL:BAB46921.1 xref: UniProtKB:Q6LEM0 xref: UniProtKB:Q7Z5E8 xref: UniProtKB:Q92560 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017124 ! BAP1_human relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0063724 ! BAP1_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0063725 ! BAP1_HUMAN-Phosphothreonine487 relationship: transforms_into CCO:B0063726 ! BAP1_HUMAN-Phosphoserine489 relationship: transforms_into CCO:B0063727 ! BAP1_HUMAN-Phosphoserine583 relationship: transforms_into CCO:B0063728 ! BAP1_HUMAN-Phosphoserine592 relationship: transforms_into CCO:B0063729 ! BAP1_HUMAN-Phosphoserine597 [Term] id: CCO:B0058064 name: RPGF5_HUMAN def: "Rap guanine nucleotide exchange factor 5" [UniProtKB:Q92565] synonym: "Guanine nucleotide exchange factor for Rap1" EXACT [UniProtKB:Q92565] synonym: "M-Ras-regulated Rap GEF" EXACT [UniProtKB:Q92565] synonym: "MR-GEF" EXACT [UniProtKB:Q92565] synonym: "Related to Epac" EXACT [UniProtKB:Q92565] synonym: "Repac" EXACT [UniProtKB:Q92565] xref: EMBL:AAH39203.1 xref: EMBL:BAA13406.2 xref: EMBL:EAL24270.1 xref: UniProtKB:A4D140 xref: UniProtKB:Q8IXU5 xref: UniProtKB:Q92565 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019788 ! RAPGEF5_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0003522 ! Rap guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0058065 name: NR4A3_HUMAN def: "Nuclear receptor subfamily 4 group A member 3" [UniProtKB:Q92570] synonym: "Mitogen-induced nuclear orphan receptor" EXACT [UniProtKB:Q92570] synonym: "Neuron-derived orphan receptor 1" EXACT [UniProtKB:Q92570] synonym: "Nuclear hormone receptor NOR-1" EXACT [UniProtKB:Q92570] xref: EMBL:AAB02581.1 xref: EMBL:AAB36006.1 xref: EMBL:BAA11419.1 xref: EMBL:BAA28608.1 xref: EMBL:BAA31221.1 xref: EMBL:CAA61984.1 xref: EMBL:CAI95138.1 xref: EMBL:CAI95320.1 xref: UniProtKB:Q12935 xref: UniProtKB:Q14979 xref: UniProtKB:Q16420 xref: UniProtKB:Q4VXA9 xref: UniProtKB:Q92570 xref: UniProtKB:Q9UEK2 xref: UniProtKB:Q9UEK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018862 ! NR4A3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058066 name: AP3S1_HUMAN def: "AP-3 complex subunit sigma-1" [UniProtKB:Q92572] synonym: "Adapter-related protein complex 3 sigma-1 subunit" EXACT [UniProtKB:Q92572] synonym: "AP-3 complex sigma-3A subunit" EXACT [UniProtKB:Q92572] synonym: "Clathrin-associated/assembly/adapter protein, small 3" EXACT [UniProtKB:Q92572] synonym: "Sigma-3A-adaptin" EXACT [UniProtKB:Q92572] synonym: "Sigma-adaptin 3a" EXACT [UniProtKB:Q92572] synonym: "Sigma3A-adaptin" EXACT [UniProtKB:Q92572] xref: EMBL:AAD03779.1 xref: EMBL:AAH00804.1 xref: EMBL:BAA09798.1 xref: EMBL:CAA67823.1 xref: EMBL:CAG29337.1 xref: UniProtKB:O00647 xref: UniProtKB:O00676 xref: UniProtKB:O00721 xref: UniProtKB:O00727 xref: UniProtKB:Q6ICQ2 xref: UniProtKB:Q92572 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016981 ! AP3S1_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000964 ! AP-type membrane coat adaptor complex relationship: located_in CCO:C0000978 ! transport vesicle relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway [Term] id: CCO:B0058067 name: CCL17_HUMAN def: "C-C motif chemokine 17 precursor" [UniProtKB:Q92583] synonym: "CC chemokine TARC" EXACT [UniProtKB:Q92583] synonym: "Small-inducible cytokine A17" EXACT [UniProtKB:Q92583] synonym: "Thymus and activation-regulated chemokine" EXACT [UniProtKB:Q92583] xref: EMBL:AAC24308.1 xref: EMBL:AAH69107.1 xref: EMBL:AAI12067.1 xref: EMBL:AAI12069.1 xref: EMBL:BAA07824.1 xref: UniProtKB:Q2M287 xref: UniProtKB:Q92583 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017262 ! CCL17_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058068 name: MAML1_HUMAN def: "Mastermind-like protein 1" [UniProtKB:Q92585] synonym: "Mam-1" EXACT [UniProtKB:Q92585] xref: EMBL:AAF34658.1 xref: EMBL:BAA12114.2 xref: UniProtKB:Q92585 xref: UniProtKB:Q9NZ12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018563 ! MAML1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0016319 ! maml-notch physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058069 name: RCD1_HUMAN def: "Cell differentiation protein RCD1 homolog" [UniProtKB:Q92600] synonym: "Rcd-1" EXACT [UniProtKB:Q92600] xref: EMBL:AAH07102.2 xref: EMBL:BAA13508.1 xref: EMBL:EAW70625.1 xref: UniProtKB:Q92600 xref: UniProtKB:Q96IX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019657 ! RQCD1_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016707 ! map3k3-q92600 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058070 name: TBCD5_HUMAN def: "TBC1 domain family member 5" [UniProtKB:Q92609] xref: EMBL:AAH13145.1 xref: EMBL:BAA13201.2 xref: UniProtKB:A6NP25 xref: UniProtKB:Q92609 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020181 ! TBC1D5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015037 ! gabarapl2-tbc1d5 physical interaction relationship: participates_in CCO:I0015542 ! ap2m1-tbc1d5 physical interaction relationship: participates_in CCO:I0016172 ! atxn1-tbc1d5 physical interaction relationship: participates_in CCO:I0017608 ! atxn1-tbc1d5-1 physical interaction relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071226 ! TBCD5_HUMAN-Phosphothreonine42 relationship: transforms_into CCO:B0071227 ! TBCD5_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0071228 ! TBCD5_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0071229 ! TBCD5_HUMAN-Phosphothreonine45 relationship: transforms_into CCO:B0071230 ! TBCD5_HUMAN-Phosphoserine522 relationship: transforms_into CCO:B0071231 ! TBCD5_HUMAN-Phosphoserine539 relationship: transforms_into CCO:B0071232 ! TBCD5_HUMAN-Phosphoserine541 relationship: transforms_into CCO:B0071233 ! TBCD5_HUMAN-Phosphoserine544 relationship: transforms_into CCO:B0071234 ! TBCD5_HUMAN-Phosphoserine554 [Term] id: CCO:B0058071 name: ZN592_HUMAN def: "Zinc finger protein 592" [UniProtKB:Q92610] xref: EMBL:AAH94688.1 xref: EMBL:AAI12233.1 xref: EMBL:AAI12235.1 xref: EMBL:BAA13202.2 xref: EMBL:EAX01957.1 xref: UniProtKB:Q2M1T2 xref: UniProtKB:Q504Y9 xref: UniProtKB:Q92610 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020842 ! ZNF592_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072162 ! ZN592_HUMAN-Phosphothreonine137 relationship: transforms_into CCO:B0072163 ! ZN592_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0072164 ! ZN592_HUMAN-Phosphoserine145 relationship: transforms_into CCO:B0072165 ! ZN592_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0072166 ! ZN592_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0072167 ! ZN592_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0072168 ! ZN592_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0072169 ! ZN592_HUMAN-Phosphoserine460 relationship: transforms_into CCO:B0072170 ! ZN592_HUMAN-Phosphoserine573 relationship: transforms_into CCO:B0072171 ! ZN592_HUMAN-Phosphoserine691 relationship: transforms_into CCO:B0072172 ! ZN592_HUMAN-Phosphoserine1089 relationship: transforms_into CCO:B0072173 ! ZN592_HUMAN-Phosphoserine1205 relationship: transforms_into CCO:B0072174 ! ZN592_HUMAN-Phosphoserine1250 relationship: transforms_into CCO:B0072175 ! ZN592_HUMAN-Phosphoserine1255 relationship: transforms_into CCO:B0072176 ! ZN592_HUMAN-Phosphoserine1264 [Term] id: CCO:B0058072 name: MY18A_HUMAN def: "Myosin-XVIIIa" [UniProtKB:Q92614] synonym: "MAJN" EXACT [UniProtKB:Q92614] synonym: "Molecule associated with JAK3 N-terminus" EXACT [UniProtKB:Q92614] synonym: "Myosin containing a PDZ domain" EXACT [UniProtKB:Q92614] xref: EMBL:AAH39612.1 xref: EMBL:BAA13206.2 xref: EMBL:BAD66836.1 xref: EMBL:BAD66838.1 xref: EMBL:CAI45931.1 xref: UniProtKB:Q5H9U3 xref: UniProtKB:Q5W9F9 xref: UniProtKB:Q5W9G1 xref: UniProtKB:Q8IXP8 xref: UniProtKB:Q92614 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018687 ! MYO18A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019099 ! atxn1-myo18a physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0068329 ! MY18A_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0068330 ! MY18A_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0068331 ! MY18A_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0068332 ! MY18A_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0068333 ! MY18A_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0068334 ! MY18A_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0068335 ! MY18A_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0068336 ! MY18A_HUMAN-Phosphoserine1039 relationship: transforms_into CCO:B0068337 ! MY18A_HUMAN-Phosphoserine1063 relationship: transforms_into CCO:B0068338 ! MY18A_HUMAN-Phosphoserine1067 relationship: transforms_into CCO:B0068339 ! MY18A_HUMAN-Phosphoserine1070 relationship: transforms_into CCO:B0068340 ! MY18A_HUMAN-Phosphoserine1942 relationship: transforms_into CCO:B0068341 ! MY18A_HUMAN-Phosphoserine1970 relationship: transforms_into CCO:B0068342 ! MY18A_HUMAN-Phosphoserine1974 relationship: transforms_into CCO:B0068343 ! MY18A_HUMAN-Phosphoserine1998 relationship: transforms_into CCO:B0068344 ! MY18A_HUMAN-Phosphoserine2002 relationship: transforms_into CCO:B0068345 ! MY18A_HUMAN-Phosphoserine2007 relationship: transforms_into CCO:B0068346 ! MY18A_HUMAN-Phosphoserine2020 relationship: transforms_into CCO:B0068347 ! MY18A_HUMAN-Phosphoserine2036 relationship: transforms_into CCO:B0068348 ! MY18A_HUMAN-Phosphoserine2041 relationship: transforms_into CCO:B0068349 ! MY18A_HUMAN-Phosphoserine2043 relationship: transforms_into CCO:B0068350 ! MY18A_HUMAN-Phosphothreonine2045 [Term] id: CCO:B0058073 name: GCN1L_HUMAN def: "Translational activator GCN1" [UniProtKB:Q92616] synonym: "GCN1-like protein 1" EXACT [UniProtKB:Q92616] synonym: "HsGCN1" EXACT [UniProtKB:Q92616] xref: EMBL:AAC51648.1 xref: EMBL:AAC83183.1 xref: EMBL:AAD00655.1 xref: EMBL:AAD00656.1 xref: EMBL:AAH21129.1 xref: EMBL:AAH32335.1 xref: EMBL:AAH46177.1 xref: EMBL:AAH64346.1 xref: EMBL:BAA13209.2 xref: UniProtKB:O95001 xref: UniProtKB:O95651 xref: UniProtKB:Q6P2S3 xref: UniProtKB:Q86X65 xref: UniProtKB:Q8N5I5 xref: UniProtKB:Q8WU80 xref: UniProtKB:Q92616 xref: UniProtKB:Q99736 xref: UniProtKB:Q9UE60 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017896 ! GCN1L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016547 ! ikbkg-kiaa0219 physical interaction relationship: participates_in CCO:I0017024 ! tnfrsf1a-kiaa0219 physical interaction relationship: participates_in CCO:I0017050 ! tnfrsf1b-kiaa0219 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0066424 ! GCN1L_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0066425 ! GCN1L_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0066426 ! GCN1L_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0066427 ! GCN1L_HUMAN-Phosphothreonine956 [Term] id: CCO:B0058074 name: ZN516_HUMAN def: "Zinc finger protein 516" [UniProtKB:Q92618] xref: EMBL:BAA13211.2 xref: UniProtKB:Q92618 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020792 ! ZNF516_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072140 ! ZN516_HUMAN-Phosphoserine116 [Term] id: CCO:B0058075 name: HMHA1_HUMAN def: "Minor histocompatibility protein HA-1" [UniProtKB:Q92619] xref: EMBL:AAC03237.1 xref: EMBL:AAF91292.1 xref: EMBL:AAG02014.1 xref: EMBL:AAG02015.1 xref: EMBL:AAG02016.1 xref: EMBL:AAH48129.1 xref: EMBL:AAH65223.1 xref: EMBL:AAN04658.1 xref: EMBL:BAA13212.1 xref: EMBL:EAW69551.1 xref: UniProtKB:Q6P189 xref: UniProtKB:Q7LE26 xref: UniProtKB:Q86WS1 xref: UniProtKB:Q8HX84 xref: UniProtKB:Q92619 xref: UniProtKB:Q9GJN9 xref: UniProtKB:Q9GJP0 xref: UniProtKB:Q9GJP1 xref: UniProtKB:Q9MY24 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018144 ! HMHA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0066834 ! HMHA1_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0066835 ! HMHA1_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0066836 ! HMHA1_HUMAN-Phosphoserine1027 relationship: transforms_into CCO:B0066837 ! HMHA1_HUMAN-Phosphoserine1030 relationship: transforms_into CCO:B0066838 ! HMHA1_HUMAN-Phosphoserine1032 [Term] id: CCO:B0058076 name: LPAR1_HUMAN def: "Lysophosphatidic acid receptor 1" [UniProtKB:Q92633] synonym: "LPA receptor 1" EXACT [UniProtKB:Q92633] synonym: "LPA-1" EXACT [UniProtKB:Q92633] synonym: "Lysophosphatidic acid receptor Edg-2" EXACT [UniProtKB:Q92633] xref: EMBL:AAC00530.1 xref: EMBL:AAC51139.1 xref: EMBL:AAH30615.1 xref: EMBL:AAH36034.1 xref: EMBL:AAP84359.1 xref: EMBL:CAA70686.1 xref: EMBL:CAA70687.1 xref: UniProtKB:O00656 xref: UniProtKB:O00722 xref: UniProtKB:P78351 xref: UniProtKB:Q92633 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021061 ! LPAR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058077 name: FAN_HUMAN def: "Protein FAN" [UniProtKB:Q92636] synonym: "Factor associated with N-SMase activation" EXACT [UniProtKB:Q92636] synonym: "Factor associated with neutral sphingomyelinase activation" EXACT [UniProtKB:Q92636] xref: EMBL:AAH41124.1 xref: EMBL:CAA65405.1 xref: EMBL:EAW86817.1 xref: UniProtKB:Q8IW26 xref: UniProtKB:Q92636 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017762 ! NSMAF_human relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058078 name: Q92657_HUMAN def: "HP8 peptide" [UniProtKB:Q92657] xref: EMBL:CAA60698.1 xref: UniProtKB:Q92657 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021248 ! HP8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058079 name: TF3A_HUMAN def: "Transcription factor IIIA" [UniProtKB:Q92664] synonym: "Factor A" EXACT [UniProtKB:Q92664] synonym: "TFIIIA" EXACT [UniProtKB:Q92664] xref: EMBL:AAA21873.1 xref: EMBL:AAA75623.1 xref: EMBL:BAA06988.1 xref: UniProtKB:Q12963 xref: UniProtKB:Q13097 xref: UniProtKB:Q92664 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020243 ! GTF3A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000297 ! RNA polymerase III transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058080 name: Q92668_HUMAN def: "K-ras protein" [UniProtKB:Q92668] xref: EMBL:AAA36148.1 xref: UniProtKB:Q92668 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021249 ! K-ras_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058081 name: RSCA1_HUMAN def: "Regulatory solute carrier protein family 1 member 1" [UniProtKB:Q92681] synonym: "hRS1" EXACT [UniProtKB:Q92681] synonym: "Transporter regulator RS1" EXACT [UniProtKB:Q92681] xref: EMBL:CAA58058.1 xref: EMBL:CAI95731.1 xref: EMBL:EAW51744.1 xref: UniProtKB:Q92681 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019797 ! RSC1A1_human relationship: has_function CCO:F0001779 ! ion channel inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058082 name: NEUG_HUMAN def: "Neurogranin" [UniProtKB:Q92686] synonym: "Ng" EXACT [UniProtKB:Q92686] synonym: "RC3" EXACT [UniProtKB:Q92686] xref: EMBL:AAB49458.1 xref: EMBL:AAH02835.1 xref: EMBL:AAP35989.1 xref: EMBL:CAA67533.1 xref: EMBL:CAA70867.1 xref: EMBL:CAA75343.1 xref: EMBL:CAC37631.1 xref: UniProtKB:Q92686 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018757 ! NRGN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068578 ! NEUG_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0068579 ! NEUG_HUMAN-Phosphoserine36 [Term] id: CCO:B0058083 name: Q92728_HUMAN def: "Mutated retinoblastoma protein" [UniProtKB:Q92728] xref: EMBL:AAA60259.1 xref: UniProtKB:Q92728 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005454 ! RB1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058084 name: ESR2_HUMAN def: "Estrogen receptor beta" [UniProtKB:Q92731] synonym: "ER-beta" EXACT [UniProtKB:Q92731] synonym: "Nuclear receptor subfamily 3 group A member 2" EXACT [UniProtKB:Q92731] xref: EMBL:AAC03786.1 xref: EMBL:AAC05751.1 xref: EMBL:AAC05985.1 xref: EMBL:AAC15234.1 xref: EMBL:AAC25602.1 xref: EMBL:AAC25603.1 xref: EMBL:AAC39784.1 xref: EMBL:AAC39785.1 xref: EMBL:AAD32580.1 xref: EMBL:AAH24181.1 xref: EMBL:AAV31779.1 xref: EMBL:BAA24953.1 xref: EMBL:BAA31966.1 xref: EMBL:CAA67555.1 xref: UniProtKB:O60608 xref: UniProtKB:O60685 xref: UniProtKB:O60702 xref: UniProtKB:O60703 xref: UniProtKB:O75583 xref: UniProtKB:O75584 xref: UniProtKB:Q86Z31 xref: UniProtKB:Q92731 xref: UniProtKB:Q9UEV6 xref: UniProtKB:Q9UHD3 xref: UniProtKB:Q9UQK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017730 ! ESR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017649 ! hrmt1l1-esr2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: transforms_into CCO:B0065163 ! ESR2_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0065164 ! ESR2_HUMAN-Phosphotyrosine488 [Term] id: CCO:B0058085 name: RSLAA_HUMAN def: "Ras-like protein family member 10A precursor" [UniProtKB:Q92737] synonym: "Ras-like protein RRP22" EXACT [UniProtKB:Q92737] synonym: "RAS-related protein on chromosome 22" EXACT [UniProtKB:Q92737] xref: EMBL:AAH22473.1 xref: EMBL:AAH40434.1 xref: EMBL:AAH50739.1 xref: EMBL:AAH58077.1 xref: EMBL:CAA69175.1 xref: UniProtKB:Q49AU5 xref: UniProtKB:Q6PI03 xref: UniProtKB:Q92737 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019799 ! RASL10A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0070248 ! RSLAA_HUMAN-Cysteine methyl ester200 [Term] id: CCO:B0058086 name: US6NL_HUMAN def: "USP6 N-terminal-like protein" [UniProtKB:Q92738] synonym: "Related to the N-terminus of tre" EXACT [UniProtKB:Q92738] synonym: "RN-tre" EXACT [UniProtKB:Q92738] xref: EMBL:AAH42943.1 xref: EMBL:BAA02807.2 xref: UniProtKB:Q15400 xref: UniProtKB:Q7L0K9 xref: UniProtKB:Q92738 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020420 ! USP6NL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071741 ! US6NL_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0071742 ! US6NL_HUMAN-Phosphoserine396 relationship: transforms_into CCO:B0071743 ! US6NL_HUMAN-Phosphoserine546 relationship: transforms_into CCO:B0071744 ! US6NL_HUMAN-Phosphotyrosine582 relationship: transforms_into CCO:B0071745 ! US6NL_HUMAN-Phosphoserine585 relationship: transforms_into CCO:B0071746 ! US6NL_HUMAN-Phosphoserine617 relationship: transforms_into CCO:B0071747 ! US6NL_HUMAN-Phosphoserine673 relationship: transforms_into CCO:B0071748 ! US6NL_HUMAN-Phosphoserine680 relationship: transforms_into CCO:B0071749 ! US6NL_HUMAN-Phosphotyrosine710 relationship: transforms_into CCO:B0071750 ! US6NL_HUMAN-Phosphoserine716 relationship: transforms_into CCO:B0071751 ! US6NL_HUMAN-Phosphotyrosine729 [Term] id: CCO:B0058087 name: HTRA1_HUMAN def: "Serine protease HTRA1 precursor" [UniProtKB:Q92743] synonym: "EC 3.4.21.-" EXACT [UniProtKB:Q92743] synonym: "L56" EXACT [UniProtKB:Q92743] synonym: "Serine protease 11" EXACT [UniProtKB:Q92743] xref: EMBL:AAC97211.1 xref: EMBL:AAD41525.1 xref: EMBL:CAA69226.1 xref: UniProtKB:Q92743 xref: UniProtKB:Q9UNS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018170 ! HTRA1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0001273 ! negative regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway [Term] id: CCO:B0058088 name: TAF4B_HUMAN def: "Transcription initiation factor TFIID subunit 4B" [UniProtKB:Q92750] synonym: "TAFII-105" EXACT [UniProtKB:Q92750] synonym: "TAFII105" EXACT [UniProtKB:Q92750] synonym: "Transcription initiation factor TFIID 105 kDa subunit" EXACT [UniProtKB:Q92750] xref: EMBL:AAX14897.1 xref: EMBL:AAX14898.1 xref: EMBL:CAA70499.1 xref: UniProtKB:Q29YA4 xref: UniProtKB:Q29YA5 xref: UniProtKB:Q92750 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020135 ! TAF4B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058089 name: TENR_HUMAN def: "Tenascin-R precursor" [UniProtKB:Q92752] synonym: "Janusin" EXACT [UniProtKB:Q92752] synonym: "Restrictin" EXACT [UniProtKB:Q92752] synonym: "TN-R" EXACT [UniProtKB:Q92752] xref: EMBL:CAA66709.1 xref: EMBL:CAA91947.1 xref: EMBL:CAI19943.1 xref: EMBL:CAI21650.1 xref: UniProtKB:Q15568 xref: UniProtKB:Q5R3G0 xref: UniProtKB:Q92752 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020232 ! TNR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071334 ! TENR_HUMAN-Phosphoserine724 [Term] id: CCO:B0058090 name: SFRP3_HUMAN def: "Secreted frizzled-related protein 3 precursor" [UniProtKB:Q92765] synonym: "Frezzled" EXACT [UniProtKB:Q92765] synonym: "Fritz" EXACT [UniProtKB:Q92765] synonym: "Frizzled-related protein 1" EXACT [UniProtKB:Q92765] synonym: "FrzB-1" EXACT [UniProtKB:Q92765] synonym: "sFRP-3" EXACT [UniProtKB:Q92765] xref: EMBL:AAB51298.1 xref: EMBL:AAC50736.1 xref: EMBL:AAC51217.1 xref: EMBL:AAH27855.1 xref: EMBL:AAV38686.1 xref: UniProtKB:O00181 xref: UniProtKB:Q92765 xref: UniProtKB:Q99686 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019875 ! FRZB_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003594 ! Wnt-protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0058091 name: RREB1_HUMAN def: "RAS-responsive element-binding protein 1" [UniProtKB:Q92766] synonym: "Finger protein in nuclear bodies" EXACT [UniProtKB:Q92766] synonym: "Raf-responsive zinc finger protein LZ321" EXACT [UniProtKB:Q92766] synonym: "RREB-1" EXACT [UniProtKB:Q92766] synonym: "Zep-1" EXACT [UniProtKB:Q92766] synonym: "Zinc finger motif-enhancer binding-protein 1" EXACT [UniProtKB:Q92766] xref: EMBL:AAB19094.1 xref: EMBL:AAC25598.1 xref: EMBL:AAC26118.1 xref: EMBL:AAH42910.1 xref: EMBL:AAI31600.1 xref: EMBL:BAA23165.1 xref: EMBL:BAD32776.1 xref: EMBL:BAD32778.1 xref: EMBL:BAD32779.1 xref: EMBL:CAH73521.1 xref: EMBL:CAI14574.1 xref: EMBL:CAI16450.1 xref: UniProtKB:A2RRF5 xref: UniProtKB:O75567 xref: UniProtKB:O75568 xref: UniProtKB:Q5VYB2 xref: UniProtKB:Q6BEP5 xref: UniProtKB:Q6BEP6 xref: UniProtKB:Q6BEP8 xref: UniProtKB:Q86SU2 xref: UniProtKB:Q92766 xref: UniProtKB:Q9Y474 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019795 ! RREB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: transforms_into CCO:B0070180 ! RREB1_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0070181 ! RREB1_HUMAN-Phosphoserine42 relationship: transforms_into CCO:B0070182 ! RREB1_HUMAN-Phosphoserine231 relationship: transforms_into CCO:B0070183 ! RREB1_HUMAN-Phosphoserine1134 relationship: transforms_into CCO:B0070184 ! RREB1_HUMAN-Phosphoserine1135 relationship: transforms_into CCO:B0070185 ! RREB1_HUMAN-Phosphoserine1167 relationship: transforms_into CCO:B0070186 ! RREB1_HUMAN-Phosphoserine1174 relationship: transforms_into CCO:B0070187 ! RREB1_HUMAN-Phosphoserine1175 relationship: transforms_into CCO:B0070188 ! RREB1_HUMAN-Phosphoserine1219 relationship: transforms_into CCO:B0070189 ! RREB1_HUMAN-Phosphoserine1225 relationship: transforms_into CCO:B0070190 ! RREB1_HUMAN-Phosphothreonine1315 relationship: transforms_into CCO:B0070191 ! RREB1_HUMAN-Phosphoserine1388 relationship: transforms_into CCO:B0070192 ! RREB1_HUMAN-Phosphoserine1653 [Term] id: CCO:B0058092 name: DPF1_HUMAN def: "Zinc finger protein neuro-d4" [UniProtKB:Q92782] synonym: "D4, zinc and double PHD fingers family 1" EXACT [UniProtKB:Q92782] xref: EMBL:AAC50685.1 xref: UniProtKB:Q92782 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017606 ! DPF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020655 ! rpn1-dpf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0058093 name: STAM1_HUMAN def: "Signal transducing adapter molecule 1" [UniProtKB:Q92783] synonym: "STAM-1" EXACT [UniProtKB:Q92783] xref: EMBL:AAC50734.1 xref: EMBL:AAH30586.1 xref: UniProtKB:Q8N6D9 xref: UniProtKB:Q92783 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020063 ! STAM_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015837 ! hgs-stam physical interaction relationship: participates_in CCO:I0016338 ! stambp-stam-2 physical interaction relationship: participates_in CCO:I0016341 ! stambp-stam-3 physical interaction relationship: participates_in CCO:I0019463 ! stambp-stam-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070957 ! STAM1_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0070958 ! STAM1_HUMAN-Phosphotyrosine198 relationship: transforms_into CCO:B0070959 ! STAM1_HUMAN-Phosphotyrosine381 [Term] id: CCO:B0058094 name: REQU_HUMAN def: "Zinc finger protein ubi-d4" [UniProtKB:Q92785] synonym: "Apoptosis response zinc finger protein" EXACT [UniProtKB:Q92785] synonym: "D4, zinc and double PHD fingers family 2" EXACT [UniProtKB:Q92785] synonym: "Requiem" EXACT [UniProtKB:Q92785] xref: EMBL:AAB58307.1 xref: EMBL:AAB81203.1 xref: EMBL:AAC50687.1 xref: EMBL:AAH14889.1 xref: EMBL:AAO26041.1 xref: EMBL:AAP35364.1 xref: UniProtKB:Q92785 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019674 ! DPF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017249 ! relb-dpf2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: transforms_into CCO:B0069874 ! REQU_HUMAN-Phosphoserine94 relationship: transforms_into CCO:B0069875 ! REQU_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0069876 ! REQU_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0069877 ! REQU_HUMAN-Phosphothreonine176 relationship: transforms_into CCO:B0069878 ! REQU_HUMAN-Phosphoserine200 [Term] id: CCO:B0058095 name: PROX1_HUMAN def: "Prospero homeobox protein 1" [UniProtKB:Q92786] synonym: "Homeobox prospero-like protein PROX1" EXACT [UniProtKB:Q92786] synonym: "PROX-1" EXACT [UniProtKB:Q92786] xref: EMBL:AAC50656.1 xref: EMBL:AAH24201.1 xref: EMBL:BAF82865.1 xref: EMBL:CAI15309.1 xref: EMBL:EAW93360.1 xref: UniProtKB:A6NK29 xref: UniProtKB:A8K2B1 xref: UniProtKB:Q5SW76 xref: UniProtKB:Q8TB91 xref: UniProtKB:Q92786 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019518 ! PROX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069537 ! PROX1_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0069538 ! PROX1_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0069539 ! PROX1_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0069540 ! PROX1_HUMAN-Phosphoserine511 relationship: transforms_into CCO:B0069541 ! PROX1_HUMAN-Phosphoserine514 relationship: transforms_into CCO:B0069542 ! PROX1_HUMAN-Phosphothreonine650 [Term] id: CCO:B0058096 name: EZH1_HUMAN def: "Enhancer of zeste homolog 1" [UniProtKB:Q92800] synonym: "ENX-2" EXACT [UniProtKB:Q92800] xref: EMBL:AAB59574.1 xref: EMBL:AAC50778.1 xref: EMBL:AAH15882.1 xref: EMBL:AAP88784.1 xref: EMBL:BAA20842.2 xref: EMBL:BAA25019.1 xref: EMBL:EAW60870.1 xref: UniProtKB:A6NCH6 xref: UniProtKB:O43287 xref: UniProtKB:Q14459 xref: UniProtKB:Q53XP3 xref: UniProtKB:Q92800 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017750 ! EZH1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058097 name: IOD2_HUMAN def: "Type II iodothyronine deiodinase" [UniProtKB:Q92813] synonym: "5DII" EXACT [UniProtKB:Q92813] synonym: "DIOII" EXACT [UniProtKB:Q92813] synonym: "EC 1.97.1.10" EXACT [UniProtKB:Q92813] synonym: "Type 2 DI" EXACT [UniProtKB:Q92813] synonym: "Type-II 5'-deiodinase" EXACT [UniProtKB:Q92813] xref: EMBL:AAC50663.1 xref: EMBL:AAC95470.1 xref: EMBL:AAD45494.1 xref: EMBL:AAH74882.1 xref: EMBL:BAB16838.1 xref: UniProtKB:Q6B0A3 xref: UniProtKB:Q92813 xref: UniProtKB:Q9HCP8 xref: UniProtKB:Q9P1W4 xref: UniProtKB:Q9UDZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018297 ! DIO2_human relationship: has_function CCO:F0001158 ! thyroxine 5'-deiodinase activity relationship: has_function CCO:F0001897 ! selenium binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000465 ! selenocysteine incorporation [Term] id: CCO:B0058098 name: HXB13_HUMAN def: "Homeobox protein Hox-B13" [UniProtKB:Q92826] xref: EMBL:AAB39863.1 xref: EMBL:AAC50664.1 xref: EMBL:AAH07092.1 xref: EMBL:AAH70233.1 xref: EMBL:AAP36078.1 xref: UniProtKB:Q92826 xref: UniProtKB:Q96QM4 xref: UniProtKB:Q99810 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018182 ! HOXB13_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058099 name: JARD2_HUMAN def: "Protein Jumonji" [UniProtKB:Q92833] synonym: "Jumonji/ARID domain-containing protein 2" EXACT [UniProtKB:Q92833] xref: EMBL:AAC50822.1 xref: EMBL:AAH46246.1 xref: EMBL:CAI15719.1 xref: EMBL:CAI19873.1 xref: UniProtKB:Q5U5L5 xref: UniProtKB:Q92833 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018356 ! JARID2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058100 name: SHIP1_HUMAN def: "Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1" [UniProtKB:Q92835] synonym: "EC 3.1.3.n1" EXACT [UniProtKB:Q92835] synonym: "hp51CN" EXACT [UniProtKB:Q92835] synonym: "Inositol polyphosphate-5-phosphatase of 145 kDa" EXACT [UniProtKB:Q92835] synonym: "p150Ship" EXACT [UniProtKB:Q92835] synonym: "SH2 domain-containing inositol phosphatase 1" EXACT [UniProtKB:Q92835] synonym: "SH2 domain-containing inositol-5'-phosphatase 1" EXACT [UniProtKB:Q92835] synonym: "SHIP-1" EXACT [UniProtKB:Q92835] synonym: "SIP-145" EXACT [UniProtKB:Q92835] xref: EMBL:AAB49680.1 xref: EMBL:AAB53573.1 xref: EMBL:AAC50453.1 xref: EMBL:AAC50454.1 xref: EMBL:AAD00081.1 xref: EMBL:AAH62985.1 xref: EMBL:AAH99920.1 xref: EMBL:AAI13581.1 xref: EMBL:AAI13583.1 xref: EMBL:CAA67071.1 xref: UniProtKB:O00145 xref: UniProtKB:Q13544 xref: UniProtKB:Q13545 xref: UniProtKB:Q6P5A4 xref: UniProtKB:Q92656 xref: UniProtKB:Q92835 xref: UniProtKB:Q9UE80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019897 ! INPP5D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070502 ! SHIP1_HUMAN-Phosphotyrosine865 relationship: transforms_into CCO:B0070503 ! SHIP1_HUMAN-Phosphotyrosine915 relationship: transforms_into CCO:B0070504 ! SHIP1_HUMAN-Phosphoserine934 relationship: transforms_into CCO:B0070505 ! SHIP1_HUMAN-Phosphotyrosine944 relationship: transforms_into CCO:B0070506 ! SHIP1_HUMAN-Phosphotyrosine1022 [Term] id: CCO:B0058101 name: FRAT1_HUMAN def: "Proto-oncogene FRAT1" [UniProtKB:Q92837] synonym: "Frat-1" EXACT [UniProtKB:Q92837] synonym: "Frequently rearranged in advanced T-cell lymphomas" EXACT [UniProtKB:Q92837] xref: EMBL:AAB97096.2 xref: EMBL:AAH34476.1 xref: EMBL:BAB86352.1 xref: EMBL:CAI40773.1 xref: UniProtKB:Q5JTI1 xref: UniProtKB:Q8NE74 xref: UniProtKB:Q8TDW9 xref: UniProtKB:Q92837 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017832 ! FRAT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058102 name: EDA_HUMAN def: "Ectodysplasin-A" [UniProtKB:Q92838] synonym: "Ectodermal dysplasia protein" EXACT [UniProtKB:Q92838] synonym: "EDA protein" EXACT [UniProtKB:Q92838] xref: EMBL:AAC36302.1 xref: EMBL:AAC36303.1 xref: EMBL:AAC50678.1 xref: EMBL:AAC50679.1 xref: EMBL:AAC77363.1 xref: EMBL:AAC77371.1 xref: EMBL:AAC77372.1 xref: EMBL:AAC77373.1 xref: EMBL:AAC77374.1 xref: EMBL:AAC77375.1 xref: EMBL:AAC77376.1 xref: EMBL:AAI26144.1 xref: EMBL:CAI39805.1 xref: EMBL:CAI39806.2 xref: EMBL:CAI40385.2 xref: EMBL:CAI41611.1 xref: EMBL:CAI41612.2 xref: EMBL:CAM14498.1 xref: EMBL:CAM17680.1 xref: EMBL:CAM24742.1 xref: UniProtKB:A0AUZ2 xref: UniProtKB:A2A337 xref: UniProtKB:O75910 xref: UniProtKB:Q5JS00 xref: UniProtKB:Q5JUM7 xref: UniProtKB:Q92838 xref: UniProtKB:Q9UP77 xref: UniProtKB:Q9Y6L0 xref: UniProtKB:Q9Y6L1 xref: UniProtKB:Q9Y6L2 xref: UniProtKB:Q9Y6L3 xref: UniProtKB:Q9Y6L4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017657 ! EDA_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015934 ! edar-eda physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0058103 name: TANK_HUMAN def: "TRAF family member-associated NF-kappa-B activator" [UniProtKB:Q92844] synonym: "I-TRAF" EXACT [UniProtKB:Q92844] synonym: "TRAF-interacting protein" EXACT [UniProtKB:Q92844] xref: EMBL:AAC50681.1 xref: EMBL:AAC50770.1 xref: EMBL:AAH03388.1 xref: UniProtKB:Q92844 xref: UniProtKB:Q92885 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020145 ! TANK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016570 ! tank-hspa1l physical interaction relationship: participates_in CCO:I0016571 ! tank-hspa5 physical interaction relationship: participates_in CCO:I0016572 ! tank-hspa8 physical interaction relationship: participates_in CCO:I0016573 ! tank-rars physical interaction relationship: participates_in CCO:I0016574 ! tank-hspa9b physical interaction relationship: participates_in CCO:I0016575 ! tank-iars physical interaction relationship: participates_in CCO:I0016576 ! tank-kars physical interaction relationship: participates_in CCO:I0016577 ! tank-krt9 physical interaction relationship: participates_in CCO:I0016578 ! tank-nap1l1 physical interaction relationship: participates_in CCO:I0016579 ! tank-cltc physical interaction relationship: participates_in CCO:I0016580 ! tank-hsp70_1 physical interaction relationship: participates_in CCO:I0016581 ! tank-kiaa1352 physical interaction relationship: participates_in CCO:I0016582 ! tank-hnrpu physical interaction relationship: participates_in CCO:I0016583 ! tank-tbk1 physical interaction relationship: participates_in CCO:I0016584 ! tank-krt16 physical interaction relationship: participates_in CCO:I0016585 ! tank-tuba2 physical interaction relationship: participates_in CCO:I0016586 ! tank-kpnb3 physical interaction relationship: participates_in CCO:I0016587 ! tank-tank-1 physical interaction relationship: participates_in CCO:I0016588 ! tank-krt1 physical interaction relationship: participates_in CCO:I0017223 ! tank-traf2 physical interaction relationship: participates_in CCO:I0017224 ! tank-traf3 physical interaction relationship: participates_in CCO:I0017259 ! tbk1-tank-1 physical interaction relationship: participates_in CCO:I0017418 ! tank-traf3-1 direct interaction relationship: participates_in CCO:I0017419 ! tank-traf3-2 direct interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071119 ! TANK_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0071120 ! TANK_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0071121 ! TANK_HUMAN-Phosphoserine228 [Term] id: CCO:B0058104 name: KIFA3_HUMAN def: "Kinesin-associated protein 3" [UniProtKB:Q92845] synonym: "Smg GDS-associated protein" EXACT [UniProtKB:Q92845] xref: EMBL:AAC50788.1 xref: EMBL:AAH28679.1 xref: EMBL:CAH72582.1 xref: EMBL:CAI19740.1 xref: UniProtKB:Q8NHU7 xref: UniProtKB:Q92845 xref: UniProtKB:Q9H416 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018403 ! KIFAP3_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004206 ! kinesin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000828 ! kinesin II complex relationship: participates_in CCO:I0017438 ! disc1-kifap3 physical interaction relationship: participates_in CCO:I0017545 ! kifap3-a2bp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058105 name: GHSR_HUMAN def: "Growth hormone secretagogue receptor type 1" [UniProtKB:Q92847] synonym: "GH-releasing peptide receptor" EXACT [UniProtKB:Q92847] synonym: "Ghrelin receptor" EXACT [UniProtKB:Q92847] synonym: "GHRP" EXACT [UniProtKB:Q92847] synonym: "GHS-R" EXACT [UniProtKB:Q92847] xref: EMBL:AAC50653.1 xref: EMBL:AAC50654.1 xref: EMBL:AAI13548.1 xref: EMBL:AAK71539.1 xref: EMBL:AAK71540.1 xref: EMBL:AAP84357.1 xref: EMBL:AAR07907.1 xref: UniProtKB:Q14D12 xref: UniProtKB:Q92847 xref: UniProtKB:Q92848 xref: UniProtKB:Q96RJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017921 ! GHSR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000167 ! growth hormone secretagogue receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003195 ! growth hormone-releasing hormone receptor activity relationship: has_function CCO:F0003529 ! peptide hormone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: participates_in CCO:P0002100 ! negative regulation of tumor necrosis factor biosynthetic process relationship: participates_in CCO:P0002246 ! positive regulation of insulin-like growth factor receptor signaling pathway relationship: participates_in CCO:P0002350 ! negative regulation of interleukin-6 biosynthetic process relationship: participates_in CCO:P0002616 ! positive regulation of fatty acid metabolic process relationship: participates_in CCO:P0003166 ! regulation of synaptogenesis [Term] id: CCO:B0058106 name: CASPA_HUMAN def: "Caspase-10 precursor" [UniProtKB:Q92851] synonym: "Apoptotic protease Mch-4" EXACT [UniProtKB:Q92851] synonym: "CASP-10" EXACT [UniProtKB:Q92851] synonym: "EC 3.4.22.63" EXACT [UniProtKB:Q92851] synonym: "FAS-associated death domain protein interleukin-1B-converting enzyme 2" EXACT [UniProtKB:Q92851] synonym: "FLICE2" EXACT [UniProtKB:Q92851] synonym: "ICE-like apoptotic protease 4" EXACT [UniProtKB:Q92851] xref: EMBL:AAB46730.1 xref: EMBL:AAC50644.1 xref: EMBL:AAD28402.1 xref: EMBL:AAD28403.1 xref: EMBL:BAB32553.1 xref: EMBL:BAB32554.1 xref: UniProtKB:Q8WYQ8 xref: UniProtKB:Q92851 xref: UniProtKB:Q99845 xref: UniProtKB:Q9Y2U6 xref: UniProtKB:Q9Y2U7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017240 ! CASP10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016253 ! tradd-traf2-2 physical interaction relationship: participates_in CCO:I0017358 ! fadd-tnfrsf6-1 physical interaction relationship: participates_in CCO:I0017676 ! casp8-caspa-1 direct interaction relationship: participates_in CCO:I0018012 ! casp8-casp10-1 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0064084 ! CASPA_HUMAN-Phosphoserine216 [Term] id: CCO:B0058107 name: SEM4D_HUMAN def: "Semaphorin-4D precursor" [UniProtKB:Q92854] synonym: "A8" EXACT [UniProtKB:Q92854] synonym: "BB18" EXACT [UniProtKB:Q92854] synonym: "CD100 antigen" EXACT [UniProtKB:Q92854] synonym: "GR3" EXACT [UniProtKB:Q92854] xref: EMBL:AAC50810.1 xref: EMBL:AAH54500.1 xref: UniProtKB:Q7Z5S4 xref: UniProtKB:Q92854 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019867 ! SEMA4D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002950 ! positive regulation of axonogenesis relationship: transforms_into CCO:B0070370 ! SEM4D_HUMAN-Phosphoserine195 [Term] id: CCO:B0058108 name: ATOH1_HUMAN def: "Protein atonal homolog 1" [UniProtKB:Q92858] synonym: "Helix-loop-helix protein hATH-1" EXACT [UniProtKB:Q92858] xref: EMBL:AAB41305.1 xref: EMBL:AAH69145.1 xref: EMBL:AAH69594.1 xref: EMBL:AAH69604.1 xref: EMBL:AAI13624.1 xref: EMBL:AAI13626.1 xref: UniProtKB:Q14CT9 xref: UniProtKB:Q92858 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017099 ! ATOH1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0004674 ! chromatin DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002423 ! positive regulation of auditory receptor cell differentiation relationship: participates_in CCO:P0002478 ! regulation of neuron differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058109 name: OSTF1_HUMAN def: "Osteoclast-stimulating factor 1" [UniProtKB:Q92882] xref: EMBL:AAB06396.1 xref: EMBL:AAH07459.1 xref: EMBL:BAD96316.1 xref: EMBL:CAH71573.1 xref: UniProtKB:Q5W126 xref: UniProtKB:Q92882 xref: UniProtKB:Q96IJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019244 ! OSTF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069001 ! OSTF1_HUMAN-Phosphothreonine200 relationship: transforms_into CCO:B0069002 ! OSTF1_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0069003 ! OSTF1_HUMAN-Phosphoserine213 [Term] id: CCO:B0058110 name: CDS1_HUMAN def: "Phosphatidate cytidylyltransferase 1" [UniProtKB:Q92903] synonym: "CDP-DAG synthase 1" EXACT [UniProtKB:Q92903] synonym: "CDP-DG synthetase 1" EXACT [UniProtKB:Q92903] synonym: "CDP-diacylglycerol synthase 1" EXACT [UniProtKB:Q92903] synonym: "CDP-diglyceride pyrophosphorylase 1" EXACT [UniProtKB:Q92903] synonym: "CDP-diglyceride synthetase 1" EXACT [UniProtKB:Q92903] synonym: "CDS 1" EXACT [UniProtKB:Q92903] synonym: "CTP:phosphatidate cytidylyltransferase 1" EXACT [UniProtKB:Q92903] synonym: "EC 2.7.7.41" EXACT [UniProtKB:Q92903] xref: EMBL:AAC50735.1 xref: EMBL:AAC51184.1 xref: EMBL:AAH74833.1 xref: EMBL:AAH74881.1 xref: UniProtKB:O00163 xref: UniProtKB:Q92903 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017321 ! CDS1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000613 ! diacylglycerol cholinephosphotransferase activity relationship: has_function CCO:F0000985 ! phosphatidate cytidylyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058111 name: DAZL_HUMAN def: "Deleted in azoospermia-like" [UniProtKB:Q92904] synonym: "DAZ homolog" EXACT [UniProtKB:Q92904] synonym: "DAZ-like autosomal" EXACT [UniProtKB:Q92904] synonym: "Deleted in azoospermia-like 1" EXACT [UniProtKB:Q92904] synonym: "SPGY-like-autosomal" EXACT [UniProtKB:Q92904] xref: EMBL:AAB39935.1 xref: EMBL:AAB63596.1 xref: EMBL:AAB84361.1 xref: EMBL:AAC50813.1 xref: EMBL:AAH27595.1 xref: UniProtKB:O15396 xref: UniProtKB:Q92904 xref: UniProtKB:Q92909 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017524 ! DAZL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001952 ! translation activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018395 ! daz1-dazl-1 physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0002631 ! positive regulation of translational initiation [Term] id: CCO:B0058112 name: M4K1_HUMAN def: "Mitogen-activated protein kinase kinase kinase kinase 1" [UniProtKB:Q92918] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q92918] synonym: "Hematopoietic progenitor kinase" EXACT [UniProtKB:Q92918] synonym: "MAPK/ERK kinase kinase kinase 1" EXACT [UniProtKB:Q92918] synonym: "MEK kinase kinase 1" EXACT [UniProtKB:Q92918] synonym: "MEKKK 1" EXACT [UniProtKB:Q92918] xref: EMBL:AAB97983.1 xref: UniProtKB:Q92918 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018550 ! MAP4K1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015914 ! map4k1-crkl-2 physical interaction relationship: participates_in CCO:I0015915 ! map4k1-crkl-3 physical interaction relationship: participates_in CCO:I0015917 ! map4k1-crkl-6 physical interaction relationship: participates_in CCO:I0016141 ! map4k1-crk-2 physical interaction relationship: participates_in CCO:I0016150 ! map4k1-crkl-4 physical interaction relationship: participates_in CCO:I0016247 ! map4k1-crkl-5 physical interaction relationship: participates_in CCO:P0000409 ! activation of MAPKKK activity relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0002424 ! regulation of hemocyte differentiation relationship: transforms_into CCO:B0067822 ! M4K1_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0067823 ! M4K1_HUMAN-Phosphoserine368 relationship: transforms_into CCO:B0067824 ! M4K1_HUMAN-Phosphoserine374 relationship: transforms_into CCO:B0067825 ! M4K1_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0067826 ! M4K1_HUMAN-Phosphotyrosine381 relationship: transforms_into CCO:B0067827 ! M4K1_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0067828 ! M4K1_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0067829 ! M4K1_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0067830 ! M4K1_HUMAN-Phosphoserine586 [Term] id: CCO:B0058113 name: Q92942_HUMAN def: "RalGDS-like" [UniProtKB:Q92942] xref: EMBL:AAC50818.1 xref: UniProtKB:Q92942 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019694 ! RGL2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058114 name: FUBP2_HUMAN def: "Far upstream element-binding protein 2" [UniProtKB:Q92945] synonym: "FUSE-binding protein 2" EXACT [UniProtKB:Q92945] synonym: "KH type-splicing regulatory protein" EXACT [UniProtKB:Q92945] synonym: "KSRP" EXACT [UniProtKB:Q92945] synonym: "p75" EXACT [UniProtKB:Q92945] xref: EMBL:AAB53222.1 xref: EMBL:AAC50892.1 xref: EMBL:AAD29861.1 xref: EMBL:AAD29862.1 xref: EMBL:AAH85004.1 xref: EMBL:BAD92899.1 xref: UniProtKB:O00301 xref: UniProtKB:Q59EZ9 xref: UniProtKB:Q5U4P6 xref: UniProtKB:Q92945 xref: UniProtKB:Q9UNT5 xref: UniProtKB:Q9UQH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017845 ! KHSRP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066292 ! FUBP2_HUMAN-Phosphothreonine100 relationship: transforms_into CCO:B0066293 ! FUBP2_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0066294 ! FUBP2_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0066295 ! FUBP2_HUMAN-Phosphoserine274 relationship: transforms_into CCO:B0066296 ! FUBP2_HUMAN-Phosphoserine480 relationship: transforms_into CCO:B0066297 ! FUBP2_HUMAN-Phosphoserine670 [Term] id: CCO:B0058115 name: PRG4_HUMAN def: "Proteoglycan 4 precursor" [UniProtKB:Q92954] synonym: "Lubricin" EXACT [UniProtKB:Q92954] synonym: "Megakaryocyte-stimulating factor" EXACT [UniProtKB:Q92954] synonym: "Superficial zone proteoglycan" EXACT [UniProtKB:Q92954] xref: EMBL:AAB09089.1 xref: EMBL:AAT74745.1 xref: EMBL:AAT74746.1 xref: EMBL:BAD18580.1 xref: EMBL:CAC36090.1 xref: UniProtKB:Q6DNC4 xref: UniProtKB:Q6DNC5 xref: UniProtKB:Q6ZMZ5 xref: UniProtKB:Q92954 xref: UniProtKB:Q9BX49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019507 ! PRG4_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0069498 ! PRG4_HUMAN-Phosphothreonine540 [Term] id: CCO:B0058116 name: SNPC3_HUMAN def: "snRNA-activating protein complex subunit 3" [UniProtKB:Q92966] synonym: "Proximal sequence element-binding transcription factor subunit beta" EXACT [UniProtKB:Q92966] synonym: "PSE-binding factor subunit beta" EXACT [UniProtKB:Q92966] synonym: "PTF subunit beta" EXACT [UniProtKB:Q92966] synonym: "Small nuclear RNA-activating complex polypeptide 3" EXACT [UniProtKB:Q92966] synonym: "SNAPc 50 kDa subunit" EXACT [UniProtKB:Q92966] synonym: "SNAPc subunit 3" EXACT [UniProtKB:Q92966] synonym: "snRNA-activating protein complex 50 kDa subunit" EXACT [UniProtKB:Q92966] xref: EMBL:AAC50948.1 xref: EMBL:AAD09214.1 xref: EMBL:AAH14985.1 xref: EMBL:AAI08744.1 xref: EMBL:AAI21012.1 xref: EMBL:AAI21013.1 xref: EMBL:CAI13285.1 xref: UniProtKB:Q2VPI6 xref: UniProtKB:Q5T285 xref: UniProtKB:Q92966 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019966 ! SNAPC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070693 ! SNPC3_HUMAN-Phosphoserine74 [Term] id: CCO:B0058117 name: GLMN_HUMAN def: "Glomulin" [UniProtKB:Q92990] synonym: "FAP" EXACT [UniProtKB:Q92990] synonym: "FK506-binding protein-associated protein" EXACT [UniProtKB:Q92990] synonym: "FKBP-associated protein" EXACT [UniProtKB:Q92990] xref: EMBL:AAC50908.1 xref: EMBL:AAH01257.1 xref: EMBL:CAC69882.1 xref: EMBL:CAC82938.1 xref: EMBL:CAC88124.1 xref: UniProtKB:Q92990 xref: UniProtKB:Q9BVE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017929 ! GLMN_human relationship: has_function CCO:F0001472 ! hepatocyte growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0020611 ! nsfl1c-glmn physical interaction relationship: participates_in CCO:P0002023 ! regulation of gene expression, epigenetic relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation relationship: participates_in CCO:P0002059 ! positive regulation of phosphorylation relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process [Term] id: CCO:B0058118 name: DVL3_HUMAN def: "Segment polarity protein dishevelled homolog DVL-3" [UniProtKB:Q92997] synonym: "Dishevelled-3" EXACT [UniProtKB:Q92997] synonym: "DSH homolog 3" EXACT [UniProtKB:Q92997] xref: EMBL:AAB47447.1 xref: EMBL:AAB65244.1 xref: EMBL:AAB84228.1 xref: EMBL:AAH32459.1 xref: EMBL:BAA13199.2 xref: UniProtKB:O14642 xref: UniProtKB:Q13531 xref: UniProtKB:Q8N5E9 xref: UniProtKB:Q92607 xref: UniProtKB:Q92997 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017646 ! DVL3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020546 ! dvl3-ly6h physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058119 name: Q93003_HUMAN def: "Adenosine receptor subtype A2a" [UniProtKB:Q93003] xref: EMBL:AAB18370.1 xref: UniProtKB:Q93003 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021250 ! hA2aR_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000164 ! adenosine receptor activity, G-protein coupled relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003194 ! gastric inhibitory peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058120 name: IGSF2_HUMAN def: "Immunoglobulin superfamily member 2 precursor" [UniProtKB:Q93033] synonym: "CD101 antigen" EXACT [UniProtKB:Q93033] synonym: "Cell surface glycoprotein V7" EXACT [UniProtKB:Q93033] synonym: "EWI-101" EXACT [UniProtKB:Q93033] synonym: "Glu-Trp-Ile EWI motif-containing protein 101" EXACT [UniProtKB:Q93033] xref: EMBL:CAA83923.1 xref: UniProtKB:Q15856 xref: UniProtKB:Q93033 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018240 ! IGSF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020341 ! igsf2-sfrs5 physical interaction relationship: participates_in CCO:I0020342 ! igsf2-sh3gl3 physical interaction relationship: participates_in CCO:I0020343 ! igsf2-st13 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0058121 name: TNR25_HUMAN def: "Tumor necrosis factor receptor superfamily member 25 precursor" [UniProtKB:Q93038] synonym: "Apo-3" EXACT [UniProtKB:Q93038] synonym: "Apoptosis-inducing receptor AIR" EXACT [UniProtKB:Q93038] synonym: "Apoptosis-mediating receptor DR3" EXACT [UniProtKB:Q93038] synonym: "Apoptosis-mediating receptor TRAMP" EXACT [UniProtKB:Q93038] synonym: "Death domain receptor 3" EXACT [UniProtKB:Q93038] synonym: "LARD" EXACT [UniProtKB:Q93038] synonym: "Lymphocyte-associated receptor of death" EXACT [UniProtKB:Q93038] synonym: "WSL protein" EXACT [UniProtKB:Q93038] synonym: "WSL-1 protein" EXACT [UniProtKB:Q93038] xref: EMBL:AAB39714.1 xref: EMBL:AAB40918.1 xref: EMBL:AAB41432.1 xref: EMBL:AAB41433.1 xref: EMBL:AAB41434.1 xref: EMBL:AAB41435.1 xref: EMBL:AAB82288.1 xref: EMBL:AAC39556.1 xref: EMBL:AAC50819.1 xref: EMBL:AAC51192.1 xref: EMBL:AAC51193.1 xref: EMBL:AAC51306.1 xref: EMBL:AAC51307.1 xref: EMBL:AAC51308.1 xref: EMBL:AAC51309.1 xref: EMBL:AAC51310.1 xref: EMBL:AAC51311.1 xref: EMBL:AAC51312.1 xref: EMBL:AAC51313.1 xref: EMBL:AAC51314.1 xref: EMBL:AAC51315.1 xref: EMBL:AAC51316.1 xref: EMBL:AAO63495.1 xref: EMBL:AAQ88676.1 xref: EMBL:BAB40662.1 xref: EMBL:BAB40663.1 xref: EMBL:CAA70559.1 xref: EMBL:CAA70560.1 xref: EMBL:CAA70561.1 xref: UniProtKB:O00275 xref: UniProtKB:O00276 xref: UniProtKB:O00277 xref: UniProtKB:O00278 xref: UniProtKB:O00279 xref: UniProtKB:O00280 xref: UniProtKB:O14865 xref: UniProtKB:O14866 xref: UniProtKB:P78507 xref: UniProtKB:P78515 xref: UniProtKB:Q92983 xref: UniProtKB:Q93036 xref: UniProtKB:Q93037 xref: UniProtKB:Q93038 xref: UniProtKB:Q99722 xref: UniProtKB:Q99830 xref: UniProtKB:Q99831 xref: UniProtKB:Q9BY86 xref: UniProtKB:Q9UME0 xref: UniProtKB:Q9UME1 xref: UniProtKB:Q9UME5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020317 ! TNFRSF25_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001358 ! tumor necrosis factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0058122 name: P2RX5_HUMAN def: "P2X purinoceptor 5" [UniProtKB:Q93086] synonym: "ATP receptor" EXACT [UniProtKB:Q93086] synonym: "P2X5" EXACT [UniProtKB:Q93086] synonym: "Purinergic receptor" EXACT [UniProtKB:Q93086] xref: EMBL:AAB08576.1 xref: EMBL:AAB08577.1 xref: EMBL:AAC28645.1 xref: EMBL:AAC51931.1 xref: EMBL:AAF43105.1 xref: EMBL:AAF43106.1 xref: EMBL:AAH39015.1 xref: EMBL:BAD92860.1 xref: EMBL:BAF83578.1 xref: UniProtKB:O43450 xref: UniProtKB:O75540 xref: UniProtKB:Q59F38 xref: UniProtKB:Q8IXW4 xref: UniProtKB:Q93086 xref: UniProtKB:Q93087 xref: UniProtKB:Q9NZV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019262 ! P2RX5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling relationship: transforms_into CCO:B0069014 ! P2RX5_HUMAN-Phosphotyrosine55 [Term] id: CCO:B0058123 name: BHMT1_HUMAN def: "Betaine--homocysteine S-methyltransferase 1" [UniProtKB:Q93088] synonym: "EC 2.1.1.5" EXACT [UniProtKB:Q93088] xref: EMBL:AAC50668.1 xref: EMBL:AAD22043.1 xref: EMBL:AAH12616.1 xref: UniProtKB:Q93088 xref: UniProtKB:Q9UNI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017150 ! BHMT_human relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002235 ! homocysteine S-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006462 ! betaine-homocysteine S-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015840 ! bhmt-bhmt physical interaction relationship: participates_in CCO:P0002911 ! regulation of homocysteine metabolic process [Term] id: CCO:B0058124 name: WNT2B_HUMAN def: "Protein Wnt-2b precursor" [UniProtKB:Q93097] synonym: "Wnt-13" EXACT [UniProtKB:Q93097] xref: EMBL:AAC39552.1 xref: EMBL:BAB11984.1 xref: EMBL:BAB11985.1 xref: EMBL:CAA96283.1 xref: UniProtKB:O14903 xref: UniProtKB:Q93097 xref: UniProtKB:Q9HDC1 xref: UniProtKB:Q9HDC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020485 ! WNT2B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058125 name: WNT8B_HUMAN def: "Protein Wnt-8b precursor" [UniProtKB:Q93098] xref: EMBL:BAB83924.1 xref: EMBL:CAA63017.1 xref: EMBL:CAA71968.1 xref: EMBL:CAA71994.1 xref: EMBL:CAH71991.1 xref: EMBL:CAH73565.1 xref: UniProtKB:O00771 xref: UniProtKB:Q5VX55 xref: UniProtKB:Q8WYK9 xref: UniProtKB:Q93098 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020496 ! WNT8B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058126 name: UCN3_HUMAN def: "Urocortin-3 precursor" [UniProtKB:Q969E3] synonym: "Stresscopin" EXACT [UniProtKB:Q969E3] synonym: "Ucn III" EXACT [UniProtKB:Q969E3] synonym: "Urocortin III" EXACT [UniProtKB:Q969E3] xref: EMBL:AAH69530.1 xref: EMBL:AAI00869.1 xref: EMBL:AAI00870.1 xref: EMBL:AAI00871.1 xref: EMBL:AAK11729.1 xref: EMBL:AAK67317.1 xref: UniProtKB:Q496H2 xref: UniProtKB:Q969E3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020404 ! UCN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway relationship: transforms_into CCO:B0071711 ! UCN3_HUMAN-Isoleucine amide157 [Term] id: CCO:B0058127 name: TCAL3_HUMAN def: "Transcription elongation factor A protein-like 3" [UniProtKB:Q969E4] synonym: "TCEA-like protein 3" EXACT [UniProtKB:Q969E4] synonym: "Transcription elongation factor S-II protein-like 3" EXACT [UniProtKB:Q969E4] xref: EMBL:AAH07622.1 xref: EMBL:AAH08703.1 xref: EMBL:AAQ13592.1 xref: EMBL:BAC05318.1 xref: EMBL:CAI42029.1 xref: UniProtKB:Q969E4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020202 ! TCEAL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071252 ! TCAL3_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0071253 ! TCAL3_HUMAN-Phosphoserine65 [Term] id: CCO:B0058128 name: NKD2_HUMAN def: "Protein naked cuticle homolog 2" [UniProtKB:Q969F2] synonym: "hNkd2" EXACT [UniProtKB:Q969F2] synonym: "Naked-2" EXACT [UniProtKB:Q969F2] xref: EMBL:AAH04940.1 xref: EMBL:AAH12176.1 xref: EMBL:AAK57486.1 xref: EMBL:BAB70501.1 xref: UniProtKB:Q969F2 xref: UniProtKB:Q96EK8 xref: UniProtKB:Q9BSN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018790 ! NKD2_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058129 name: KISSR_HUMAN def: "KiSS-1 receptor" [UniProtKB:Q969F8] synonym: "G-protein coupled receptor 54" EXACT [UniProtKB:Q969F8] synonym: "hOT7T175" EXACT [UniProtKB:Q969F8] synonym: "Hypogonadotropin-1" EXACT [UniProtKB:Q969F8] synonym: "KiSS-1R" EXACT [UniProtKB:Q969F8] synonym: "Kisspeptins receptor" EXACT [UniProtKB:Q969F8] synonym: "Metastin receptor" EXACT [UniProtKB:Q969F8] xref: EMBL:AAK33126.1 xref: EMBL:AAK83235.1 xref: EMBL:AAP82929.1 xref: EMBL:AAP82930.1 xref: EMBL:BAB55446.1 xref: EMBL:CAC40817.1 xref: UniProtKB:Q969F8 xref: UniProtKB:Q96QG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018404 ! KISS1R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001259 ! negative regulation of cell migration [Term] id: CCO:B0058130 name: NKD1_HUMAN def: "Protein naked cuticle homolog 1" [UniProtKB:Q969G9] synonym: "hNkd" EXACT [UniProtKB:Q969G9] synonym: "hNkd1" EXACT [UniProtKB:Q969G9] synonym: "Naked-1" EXACT [UniProtKB:Q969G9] xref: EMBL:AAH51288.1 xref: EMBL:AAK57484.1 xref: EMBL:AAL32374.1 xref: EMBL:AAL55768.1 xref: EMBL:BAB70500.1 xref: UniProtKB:Q8WZ08 xref: UniProtKB:Q969G9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018789 ! NKD1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058131 name: CNKR1_HUMAN def: "Connector enhancer of kinase suppressor of ras 1" [UniProtKB:Q969H4] synonym: "CNK homolog protein 1" EXACT [UniProtKB:Q969H4] synonym: "Connector enhancer of KSR-like" EXACT [UniProtKB:Q969H4] synonym: "Connector enhancer of KSR1" EXACT [UniProtKB:Q969H4] synonym: "hCNK1" EXACT [UniProtKB:Q969H4] xref: EMBL:AAC80558.1 xref: EMBL:AAH11604.1 xref: EMBL:AAH12797.1 xref: EMBL:AAP35546.1 xref: UniProtKB:O95381 xref: UniProtKB:Q969H4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017405 ! CNKSR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015010 ! cnksr1-pscd3 physical interaction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: transforms_into CCO:B0064416 ! CNKR1_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0064417 ! CNKR1_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0064418 ! CNKR1_HUMAN-Phosphoserine314 [Term] id: CCO:B0058132 name: CS010_HUMAN def: "UPF0556 protein C19orf10 precursor" [UniProtKB:Q969H8] synonym: "IL-25" EXACT [UniProtKB:Q969H8] synonym: "Interleukin-25" EXACT [UniProtKB:Q969H8] synonym: "Stromal cell-derived growth factor SF20" EXACT [UniProtKB:Q969H8] xref: EMBL:AAC27824.1 xref: EMBL:AAC33800.1 xref: EMBL:AAH03639.2 xref: EMBL:AAH10129.1 xref: EMBL:AAH14655.1 xref: EMBL:CAB96947.1 xref: EMBL:CAB96948.1 xref: UniProtKB:O75256 xref: UniProtKB:O75272 xref: UniProtKB:Q969H8 xref: UniProtKB:Q9BTK7 xref: UniProtKB:Q9NP69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017470 ! C19orf10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: participates_in CCO:I0017524 ! c19orf10-ubqln4 physical interaction relationship: participates_in CCO:I0020259 ! c19orf10-bat3 physical interaction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0058133 name: ZKSC4_HUMAN def: "Zinc finger protein with KRAB and SCAN domains 4" [UniProtKB:Q969J2] synonym: "P373c6.1" EXACT [UniProtKB:Q969J2] synonym: "Zinc finger protein 307" EXACT [UniProtKB:Q969J2] xref: EMBL:AAH14031.1 xref: EMBL:AAV41023.1 xref: EMBL:CAC69823.1 xref: EMBL:EAX03142.1 xref: UniProtKB:Q5U7L4 xref: UniProtKB:Q969J2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020611 ! ZKSCAN4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072043 ! ZKSC4_HUMAN-Phosphoserine165 [Term] id: CCO:B0058134 name: I22R2_HUMAN def: "Interleukin-22 receptor subunit alpha-2 precursor" [UniProtKB:Q969J5] synonym: "CRF2-10" EXACT [UniProtKB:Q969J5] synonym: "CRF2-S1" EXACT [UniProtKB:Q969J5] synonym: "Cytokine receptor family class II member 10" EXACT [UniProtKB:Q969J5] synonym: "Cytokine receptor family type 2, soluble 1" EXACT [UniProtKB:Q969J5] synonym: "IL-22R-alpha-2" EXACT [UniProtKB:Q969J5] synonym: "IL22BP" EXACT [UniProtKB:Q969J5] synonym: "Interleukin-22-binding protein" EXACT [UniProtKB:Q969J5] xref: EMBL:AAK85714.1 xref: EMBL:AAK85715.1 xref: EMBL:AAK85716.1 xref: EMBL:AAK91775.1 xref: EMBL:AAQ88478.1 xref: EMBL:AAQ89097.1 xref: EMBL:AAV31775.1 xref: EMBL:CAC83097.1 xref: EMBL:CAC85634.1 xref: EMBL:CAC85635.1 xref: EMBL:CAI21589.1 xref: EMBL:CAI21590.1 xref: EMBL:CAI21591.1 xref: UniProtKB:Q6UWM1 xref: UniProtKB:Q969J5 xref: UniProtKB:Q96A41 xref: UniProtKB:Q96QR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018200 ! IL22RA2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0005606 ! interleukin-22 binding relationship: has_function CCO:F0005607 ! interleukin-22 receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0002081 ! regulation of tyrosine phosphorylation of Stat3 protein [Term] id: CCO:B0058135 name: TAAR8_HUMAN def: "Trace amine-associated receptor 8" [UniProtKB:Q969N4] synonym: "G-protein coupled receptor 102" EXACT [UniProtKB:Q969N4] synonym: "TaR-5" EXACT [UniProtKB:Q969N4] synonym: "Trace amine receptor 5" EXACT [UniProtKB:Q969N4] xref: EMBL:AAH69166.1 xref: EMBL:AAK71244.1 xref: EMBL:AAL26487.1 xref: EMBL:AAO24659.1 xref: EMBL:CAH72098.1 xref: UniProtKB:Q5VUQ0 xref: UniProtKB:Q969N4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020125 ! TAAR8_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058136 name: IGSF8_HUMAN def: "Immunoglobulin superfamily member 8 precursor" [UniProtKB:Q969P0] synonym: "CD316 antigen" EXACT [UniProtKB:Q969P0] synonym: "CD81 partner 3" EXACT [UniProtKB:Q969P0] synonym: "EWI-2" EXACT [UniProtKB:Q969P0] synonym: "Glu-Trp-Ile EWI motif-containing protein 2" EXACT [UniProtKB:Q969P0] synonym: "KCT-4" EXACT [UniProtKB:Q969P0] synonym: "Keratinocytes-associated transmembrane protein 4" EXACT [UniProtKB:Q969P0] synonym: "LIR-D1" EXACT [UniProtKB:Q969P0] xref: EMBL:AAH04108.2 xref: EMBL:AAH53881.1 xref: EMBL:AAK92220.1 xref: EMBL:AAL01052.1 xref: EMBL:AAM94901.1 xref: EMBL:AAO13163.1 xref: EMBL:BAB71027.1 xref: UniProtKB:Q8NG09 xref: UniProtKB:Q969P0 xref: UniProtKB:Q96DP4 xref: UniProtKB:Q9BTG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018242 ! IGSF8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0067062 ! IGSF8_HUMAN-Phosphoserine12 [Term] id: CCO:B0058137 name: TRI63_HUMAN def: "E3 ubiquitin-protein ligase TRIM63" [UniProtKB:Q969Q1] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q969Q1] synonym: "Iris RING finger protein" EXACT [UniProtKB:Q969Q1] synonym: "MURF-1" EXACT [UniProtKB:Q969Q1] synonym: "MuRF1" EXACT [UniProtKB:Q969Q1] synonym: "Muscle-specific RING finger protein 1" EXACT [UniProtKB:Q969Q1] synonym: "RING finger protein 28" EXACT [UniProtKB:Q969Q1] synonym: "Striated muscle RING zinc finger protein" EXACT [UniProtKB:Q969Q1] synonym: "Tripartite motif-containing protein 63" EXACT [UniProtKB:Q969Q1] xref: EMBL:AAH80529.1 xref: EMBL:AAK39519.1 xref: EMBL:AAK52497.1 xref: EMBL:BAB71318.1 xref: EMBL:CAC33173.1 xref: EMBL:CAC81706.1 xref: EMBL:CAI17133.1 xref: UniProtKB:Q5T2I1 xref: UniProtKB:Q969Q1 xref: UniProtKB:Q96BD3 xref: UniProtKB:Q96KD9 xref: UniProtKB:Q9BYV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020359 ! TRIM63_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004666 ! titin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001766 ! contractile fiber relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058138 name: ARL11_HUMAN def: "ADP-ribosylation factor-like protein 11" [UniProtKB:Q969Q4] synonym: "ADP-ribosylation factor-like tumor suppressor protein 1" EXACT [UniProtKB:Q969Q4] xref: EMBL:AAH13150.1 xref: EMBL:AAP19650.1 xref: EMBL:BAC03621.1 xref: EMBL:CAI40715.1 xref: UniProtKB:Q969Q4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017033 ! ARL11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0063595 ! ARL11_HUMAN-Phosphoserine6 [Term] id: CCO:B0058139 name: RAB24_HUMAN def: "Ras-related protein Rab-24" [UniProtKB:Q969Q5] xref: EMBL:AAH10006.1 xref: EMBL:AAH15534.1 xref: EMBL:AAH21263.1 xref: EMBL:AAP35932.1 xref: EMBL:AAP97202.1 xref: EMBL:CAD38754.1 xref: UniProtKB:Q7Z4Z7 xref: UniProtKB:Q969Q5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019581 ! RAB24_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058140 name: LMBL2_HUMAN def: "Lethal(3)malignant brain tumor-like 2 protein" [UniProtKB:Q969R5] synonym: "H-l(3)mbt-like protein" EXACT [UniProtKB:Q969R5] synonym: "L(3)mbt-like 2 protein" EXACT [UniProtKB:Q969R5] xref: EMBL:AAH17191.1 xref: EMBL:BAB84917.1 xref: EMBL:BAC04936.1 xref: EMBL:CAB66499.2 xref: EMBL:CAC37794.1 xref: EMBL:CAC37795.1 xref: EMBL:CAG30368.1 xref: EMBL:CAI22654.1 xref: EMBL:CAI23036.1 xref: UniProtKB:Q8TEN1 xref: UniProtKB:Q969R5 xref: UniProtKB:Q96SC4 xref: UniProtKB:Q9BQI2 xref: UniProtKB:Q9UGS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018505 ! L3MBTL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014956 ! c1orf149-l3mbtl2 physical interaction relationship: participates_in CCO:I0014987 ! l3mbtl2-phf10 physical interaction relationship: participates_in CCO:I0015513 ! l3mbtl2-stam2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0067683 ! LMBL2_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0067684 ! LMBL2_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0067685 ! LMBL2_HUMAN-Phosphothreonine66 relationship: transforms_into CCO:B0067686 ! LMBL2_HUMAN-Phosphothreonine76 relationship: transforms_into CCO:B0067687 ! LMBL2_HUMAN-Phosphoserine683 relationship: transforms_into CCO:B0067688 ! LMBL2_HUMAN-Phosphoserine688 relationship: transforms_into CCO:B0067689 ! LMBL2_HUMAN-Phosphoserine689 [Term] id: CCO:B0058141 name: MCHR2_HUMAN def: "Melanin-concentrating hormone receptor 2" [UniProtKB:Q969V1] synonym: "G-protein coupled receptor 145" EXACT [UniProtKB:Q969V1] synonym: "GPRv17" EXACT [UniProtKB:Q969V1] synonym: "MCH receptor 2" EXACT [UniProtKB:Q969V1] synonym: "MCH-2R" EXACT [UniProtKB:Q969V1] synonym: "MCH-R2" EXACT [UniProtKB:Q969V1] synonym: "MCH2" EXACT [UniProtKB:Q969V1] synonym: "MCH2R" EXACT [UniProtKB:Q969V1] synonym: "MCHR-2" EXACT [UniProtKB:Q969V1] xref: EMBL:AAH95515.1 xref: EMBL:AAK32193.1 xref: EMBL:AAK38157.1 xref: EMBL:AAL05528.1 xref: EMBL:AAS72374.1 xref: EMBL:BAB55677.1 xref: EMBL:BAB87842.1 xref: EMBL:CAH70022.1 xref: UniProtKB:Q5VTV7 xref: UniProtKB:Q6Q377 xref: UniProtKB:Q969V1 xref: UniProtKB:Q9BXA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018588 ! MCHR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058142 name: MUL1_HUMAN def: "Mitochondrial ubiquitin ligase activator of NFKB 1" [UniProtKB:Q969V5] synonym: "E3 ubiquitin-protein ligase MUL1" EXACT [UniProtKB:Q969V5] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q969V5] synonym: "Mitochondrial-anchored protein ligase" EXACT [UniProtKB:Q969V5] synonym: "Putative NF-kappa-B-activating protein 266" EXACT [UniProtKB:Q969V5] synonym: "RING finger protein 218" EXACT [UniProtKB:Q969V5] xref: EMBL:AAH10101.1 xref: EMBL:AAH14010.1 xref: EMBL:BAB14317.1 xref: EMBL:BAC77368.1 xref: EMBL:CAD38745.1 xref: EMBL:CAH73470.1 xref: UniProtKB:Q7Z431 xref: UniProtKB:Q969V5 xref: UniProtKB:Q9H9B5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022414 ! MUL1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: located_in CCO:C0001194 ! integral to mitochondrial outer membrane relationship: participates_in CCO:I0015099 ! appbp2-c1orf166 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058143 name: MKL1_HUMAN def: "MKL/myocardin-like protein 1" [UniProtKB:Q969V6] synonym: "Megakaryoblastic leukemia 1 protein" EXACT [UniProtKB:Q969V6] synonym: "Megakaryocytic acute leukemia protein" EXACT [UniProtKB:Q969V6] synonym: "MRTF-A" EXACT [UniProtKB:Q969V6] synonym: "Myocardin-related transcription factor A" EXACT [UniProtKB:Q969V6] xref: EMBL:AAK54721.1 xref: EMBL:AAK56920.1 xref: EMBL:BAA92676.2 xref: EMBL:CAC38826.1 xref: EMBL:CAC38827.1 xref: EMBL:CAC38828.1 xref: EMBL:CAC38829.1 xref: EMBL:CAD28507.2 xref: EMBL:CAG30408.1 xref: EMBL:CAI18985.1 xref: UniProtKB:Q8TCL1 xref: UniProtKB:Q969V6 xref: UniProtKB:Q96SC5 xref: UniProtKB:Q96SC6 xref: UniProtKB:Q9P2B0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018631 ! MKL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018009 ! mkl2-mkl1-1 physical interaction relationship: participates_in CCO:I0018304 ! srf-mkl1-1 physical interaction relationship: participates_in CCO:I0019354 ! srf-mlk1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068211 ! MKL1_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0068212 ! MKL1_HUMAN-Phosphothreonine305 relationship: transforms_into CCO:B0068213 ! MKL1_HUMAN-Phosphothreonine450 relationship: transforms_into CCO:B0068214 ! MKL1_HUMAN-Phosphoserine454 [Term] id: CCO:B0058144 name: PMEPA_HUMAN def: "Transmembrane prostate androgen-induced protein" [UniProtKB:Q969W9] synonym: "Solid tumor-associated 1 protein" EXACT [UniProtKB:Q969W9] xref: EMBL:AAF86322.1 xref: EMBL:AAH15918.2 xref: EMBL:AAL09357.1 xref: EMBL:AAL16781.1 xref: EMBL:CAI19031.1 xref: EMBL:CAI23105.1 xref: UniProtKB:Q5TDR6 xref: UniProtKB:Q969W9 xref: UniProtKB:Q96B72 xref: UniProtKB:Q9UJD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019456 ! PMEPA1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017540 ! tmepai-ubqln4 physical interaction relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway [Term] id: CCO:B0058145 name: PP14A_HUMAN def: "Protein phosphatase 1 regulatory subunit 14A" [UniProtKB:Q96A00] synonym: "17 kDa PKC-potentiated inhibitory protein of PP1" EXACT [UniProtKB:Q96A00] synonym: "CPI-17" EXACT [UniProtKB:Q96A00] xref: EMBL:AAH21089.1 xref: EMBL:AAL24445.1 xref: EMBL:AAL25828.1 xref: EMBL:AAP97242.1 xref: EMBL:BAB62502.1 xref: EMBL:BAB62503.1 xref: UniProtKB:Q7Z4X7 xref: UniProtKB:Q96A00 xref: UniProtKB:Q96S54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019471 ! PPP1R14A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: transforms_into CCO:B0069440 ! PP14A_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0069441 ! PP14A_HUMAN-Phosphothreonine38 relationship: transforms_into CCO:B0069442 ! PP14A_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0069443 ! PP14A_HUMAN-Phosphoserine136 [Term] id: CCO:B0058146 name: ISL2_HUMAN def: "Insulin gene enhancer protein ISL-2" [UniProtKB:Q96A47] synonym: "Islet-2" EXACT [UniProtKB:Q96A47] xref: EMBL:AAH11967.1 xref: EMBL:AAH12136.1 xref: UniProtKB:Q96A47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018327 ! ISL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067156 ! ISL2_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0067157 ! ISL2_HUMAN-Phosphoserine157 [Term] id: CCO:B0058147 name: RERG_HUMAN def: "Ras-related and estrogen-regulated growth inhibitor" [UniProtKB:Q96A58] xref: EMBL:AAH07997.1 xref: EMBL:AAK98530.1 xref: UniProtKB:Q96A58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019676 ! RERG_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004046 ! GDP binding relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: transforms_into CCO:B0069883 ! RERG_HUMAN-Phosphothreonine177 [Term] id: CCO:B0058148 name: TIP39_HUMAN def: "Tuberoinfundibular peptide of 39 residues precursor" [UniProtKB:Q96A98] synonym: "Parathyroid hormone 2" EXACT [UniProtKB:Q96A98] synonym: "TIP39" EXACT [UniProtKB:Q96A98] xref: EMBL:AAH93995.1 xref: EMBL:AAH93997.1 xref: EMBL:AAK68689.1 xref: EMBL:AAL06597.1 xref: UniProtKB:Q96A98 xref: UniProtKB:Q96DJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020275 ! PTH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0058149 name: ISOC2_HUMAN def: "Isochorismatase domain-containing protein 2, mitochondrial precursor" [UniProtKB:Q96AB3] xref: EMBL:AAH17344.1 xref: EMBL:BAB15666.1 xref: EMBL:CAG33658.1 xref: UniProtKB:Q96AB3 xref: UniProtKB:Q9H5G0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018328 ! ISOC2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0001483 ! protein destabilization [Term] id: CCO:B0058150 name: FERM2_HUMAN def: "Fermitin family homolog 2" [UniProtKB:Q96AC1] synonym: "Kindlin-2" EXACT [UniProtKB:Q96AC1] synonym: "MIG-2" EXACT [UniProtKB:Q96AC1] synonym: "Mitogen-inducible gene 2 protein" EXACT [UniProtKB:Q96AC1] synonym: "Pleckstrin homology domain-containing family C member 1" EXACT [UniProtKB:Q96AC1] xref: EMBL:AAH17327.1 xref: EMBL:AAN75823.1 xref: EMBL:CAA80852.1 xref: EMBL:CAD61925.1 xref: UniProtKB:Q14840 xref: UniProtKB:Q86TY7 xref: UniProtKB:Q96AC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017775 ! FERMT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0066162 ! FERM2_HUMAN-Phosphoserine159 relationship: transforms_into CCO:B0066163 ! FERM2_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0066164 ! FERM2_HUMAN-Phosphoserine666 [Term] id: CCO:B0058151 name: FUBP1_HUMAN def: "Far upstream element-binding protein 1" [UniProtKB:Q96AE4] synonym: "DNA helicase V" EXACT [UniProtKB:Q96AE4] synonym: "FBP" EXACT [UniProtKB:Q96AE4] synonym: "FUSE-binding protein 1" EXACT [UniProtKB:Q96AE4] synonym: "HDH V" EXACT [UniProtKB:Q96AE4] xref: EMBL:AAA17976.2 xref: EMBL:AAH17247.1 xref: UniProtKB:Q12828 xref: UniProtKB:Q96AE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017844 ! FUBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019536 ! fubp1-tle1 physical interaction relationship: participates_in CCO:I0019590 ! fubp1-chd3 physical interaction relationship: participates_in CCO:I0019591 ! fubp1-vim physical interaction relationship: participates_in CCO:I0019723 ! fubp1-crmp1 physical interaction relationship: participates_in CCO:I0020322 ! fubp1-cugbp1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066288 ! FUBP1_HUMAN-Phosphotyrosine58 relationship: transforms_into CCO:B0066289 ! FUBP1_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0066290 ! FUBP1_HUMAN-Phosphothreonine153 relationship: transforms_into CCO:B0066291 ! FUBP1_HUMAN-Phosphoserine630 [Term] id: CCO:B0058152 name: Q96AG7_HUMAN def: "cAMP responsive element modulator" [UniProtKB:Q96AG7] xref: EMBL:AAH17117.1 xref: EMBL:AAH66342.1 xref: EMBL:CAI12141.1 xref: UniProtKB:Q96AG7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017453 ! CREM_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058153 name: RAB7B_HUMAN def: "Ras-related protein Rab-7b" [UniProtKB:Q96AH8] xref: EMBL:AAH17092.1 xref: EMBL:AAM22519.1 xref: UniProtKB:Q96AH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019606 ! RAB7B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058154 name: PBIP1_HUMAN def: "Pre-B-cell leukemia transcription factor-interacting protein 1" [UniProtKB:Q96AQ6] synonym: "Hematopoietic PBX-interacting protein" EXACT [UniProtKB:Q96AQ6] xref: EMBL:AAG02026.1 xref: EMBL:AAH16852.1 xref: EMBL:BAB14059.1 xref: EMBL:BAB14471.1 xref: EMBL:CAI13238.1 xref: EMBL:CAI13239.1 xref: EMBL:CAI13240.1 xref: EMBL:EAW53175.1 xref: EMBL:EAW53176.1 xref: UniProtKB:Q5T174 xref: UniProtKB:Q5T176 xref: UniProtKB:Q96AQ6 xref: UniProtKB:Q9H8X6 xref: UniProtKB:Q9HA02 xref: UniProtKB:Q9HD85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019313 ! PBXIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015407 ! pbxip1-tsnax physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0069144 ! PBIP1_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0069145 ! PBIP1_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0069146 ! PBIP1_HUMAN-Phosphoserine147 relationship: transforms_into CCO:B0069147 ! PBIP1_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0069148 ! PBIP1_HUMAN-Phosphothreonine152 [Term] id: CCO:B0058155 name: CIDEC_HUMAN def: "Cell death activator CIDE-3" [UniProtKB:Q96AQ7] synonym: "Cell death-inducing DFFA-like effector protein C" EXACT [UniProtKB:Q96AQ7] synonym: "Fat-specific protein FSP27 homolog" EXACT [UniProtKB:Q96AQ7] xref: EMBL:AAH16851.1 xref: EMBL:AAN32612.1 xref: EMBL:AAQ65242.1 xref: EMBL:AAR23106.1 xref: EMBL:BAB14920.1 xref: EMBL:BAB14922.1 xref: UniProtKB:Q67DW9 xref: UniProtKB:Q96AQ7 xref: UniProtKB:Q9GZY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017364 ! CIDEC_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0058156 name: ECOP_HUMAN def: "EGFR-coamplified and overexpressed protein precursor" [UniProtKB:Q96AW1] synonym: "ECop" EXACT [UniProtKB:Q96AW1] synonym: "Glioblastoma-amplified secreted protein" EXACT [UniProtKB:Q96AW1] synonym: "Putative NF-kappa-B-activating protein 055N" EXACT [UniProtKB:Q96AW1] xref: EMBL:AAH16650.1 xref: EMBL:AAK82888.1 xref: EMBL:BAC11590.1 xref: EMBL:BAC77357.1 xref: EMBL:CAB66545.1 xref: EMBL:CAG38514.1 xref: EMBL:EAL23811.1 xref: EMBL:EAW50969.1 xref: UniProtKB:Q6FIE3 xref: UniProtKB:Q8NBN8 xref: UniProtKB:Q96AW1 xref: UniProtKB:Q96RE5 xref: UniProtKB:Q9H0W4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017654 ! ECOP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058157 name: RAB37_HUMAN def: "Ras-related protein Rab-37" [UniProtKB:Q96AX2] xref: EMBL:AAH16615.1 xref: EMBL:BAC05227.1 xref: UniProtKB:Q96AX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019592 ! RAB37_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0015387 ! ewsr1-rab37 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058158 name: MIB2_HUMAN def: "E3 ubiquitin-protein ligase MIB2" [UniProtKB:Q96AX9] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q96AX9] synonym: "Mind bomb homolog 2" EXACT [UniProtKB:Q96AX9] synonym: "Novel zinc finger protein" EXACT [UniProtKB:Q96AX9] synonym: "Novelzin" EXACT [UniProtKB:Q96AX9] synonym: "Putative NF-kappa-B-activating protein 002N" EXACT [UniProtKB:Q96AX9] synonym: "Skeletrophin" EXACT [UniProtKB:Q96AX9] synonym: "Zinc finger ZZ type with ankyrin repeat domain protein 1" EXACT [UniProtKB:Q96AX9] xref: EMBL:AAH16490.1 xref: EMBL:AAH37542.1 xref: EMBL:BAB82979.1 xref: EMBL:BAB92950.1 xref: EMBL:BAC00992.1 xref: EMBL:BAC00993.1 xref: EMBL:BAC00994.1 xref: EMBL:BAC03707.1 xref: EMBL:BAC04646.1 xref: EMBL:BAC04752.1 xref: EMBL:BAC04952.1 xref: EMBL:BAC05413.1 xref: EMBL:BAC77353.1 xref: EMBL:BAG53705.1 xref: EMBL:BAG53766.1 xref: EMBL:CAD39183.1 xref: EMBL:CAM12830.1 xref: EMBL:CAM12831.1 xref: UniProtKB:A2AGM5 xref: UniProtKB:A2AGM6 xref: UniProtKB:B3KV93 xref: UniProtKB:B3KVF4 xref: UniProtKB:Q7Z437 xref: UniProtKB:Q8IY62 xref: UniProtKB:Q8N786 xref: UniProtKB:Q8N897 xref: UniProtKB:Q8N8R2 xref: UniProtKB:Q8N911 xref: UniProtKB:Q8NB36 xref: UniProtKB:Q8NCY1 xref: UniProtKB:Q8NG59 xref: UniProtKB:Q8NG60 xref: UniProtKB:Q8NG61 xref: UniProtKB:Q8NI59 xref: UniProtKB:Q8WYN1 xref: UniProtKB:Q96AX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018618 ! MIB2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: transforms_into CCO:B0068169 ! MIB2_HUMAN-Phosphothreonine200 relationship: transforms_into CCO:B0068170 ! MIB2_HUMAN-Phosphoserine202 [Term] id: CCO:B0058159 name: ISG20_HUMAN def: "Interferon-stimulated gene 20 kDa protein" [UniProtKB:Q96AZ6] synonym: "EC 3.1.13.1" EXACT [UniProtKB:Q96AZ6] synonym: "Estrogen-regulated transcript 45 protein" EXACT [UniProtKB:Q96AZ6] synonym: "Promyelocytic leukemia nuclear body-associated protein ISG20" EXACT [UniProtKB:Q96AZ6] xref: EMBL:AAB53416.1 xref: EMBL:AAH07922.1 xref: EMBL:AAH16341.1 xref: EMBL:AAP35598.1 xref: EMBL:CAA61915.2 xref: EMBL:CAG33223.1 xref: UniProtKB:O00441 xref: UniProtKB:O00586 xref: UniProtKB:Q96AZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018324 ! ISG20_human relationship: has_function CCO:F0000034 ! 3'-5'-exoribonuclease activity relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001824 ! single-stranded DNA specific 3'-5' exodeoxyribonuclease activity relationship: has_function CCO:F0002198 ! exoribonuclease II activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000818 ! PML body relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0058160 name: AKTS1_HUMAN def: "Proline-rich AKT1 substrate 1" [UniProtKB:Q96B36] synonym: "40 kDa proline-rich AKT substrate" EXACT [UniProtKB:Q96B36] xref: EMBL:AAH00031.2 xref: EMBL:AAH07416.1 xref: EMBL:AAH15562.1 xref: EMBL:AAH16043.1 xref: EMBL:AAH51844.1 xref: EMBL:BAB70937.1 xref: UniProtKB:Q96B36 xref: UniProtKB:Q96BI4 xref: UniProtKB:Q96IK7 xref: UniProtKB:Q96NG2 xref: UniProtKB:Q9BWR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016949 ! AKT1S1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020346 ! itgb3bp-akt1s1 physical interaction relationship: participates_in CCO:I0020470 ! tcea2-akt1s1 physical interaction relationship: participates_in CCO:P0002235 ! neuroprotection relationship: participates_in CCO:P0002591 ! regulation of survival gene product expression relationship: transforms_into CCO:B0065579 ! AKTS1_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0065580 ! AKTS1_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0065581 ! AKTS1_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0065582 ! AKTS1_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0065583 ! AKTS1_HUMAN-Phosphoserine202 relationship: transforms_into CCO:B0065584 ! AKTS1_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0065585 ! AKTS1_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0065586 ! AKTS1_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0065587 ! AKTS1_HUMAN-Phosphothreonine246 [Term] id: CCO:B0058161 name: CR3L1_HUMAN def: "cAMP-responsive element-binding protein 3-like protein 1" [UniProtKB:Q96BA8] synonym: "OASIS" EXACT [UniProtKB:Q96BA8] xref: EMBL:AAH14097.1 xref: EMBL:AAH15781.1 xref: EMBL:BAC01278.1 xref: EMBL:BAC11681.1 xref: UniProtKB:Q8N2D5 xref: UniProtKB:Q96BA8 xref: UniProtKB:Q96CP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017446 ! CREB3L1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058162 name: PF21A_HUMAN def: "PHD finger protein 21A" [UniProtKB:Q96BD5] synonym: "BHC80a" EXACT [UniProtKB:Q96BD5] synonym: "BRAF35-HDAC complex protein BHC80" EXACT [UniProtKB:Q96BD5] xref: EMBL:AAF64262.1 xref: EMBL:AAH15714.1 xref: EMBL:AAM09095.1 xref: EMBL:BAB13839.1 xref: EMBL:BAB14492.1 xref: EMBL:BAB21787.1 xref: EMBL:CAH10542.1 xref: UniProtKB:Q6AWA2 xref: UniProtKB:Q96BD5 xref: UniProtKB:Q9C0G7 xref: UniProtKB:Q9H8V9 xref: UniProtKB:Q9HAK6 xref: UniProtKB:Q9NZE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019372 ! PHF21A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015163 ! lpxn-phf21a physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058163 name: Q96BH8_HUMAN def: "GATA2 protein" [UniProtKB:Q96BH8] synonym: "GATA binding protein 2, isoform CRA_b" EXACT [UniProtKB:Q96BH8] xref: EMBL:AAH15577.1 xref: EMBL:AAH18988.1 xref: EMBL:AAH51272.1 xref: EMBL:EAW79314.1 xref: UniProtKB:Q96BH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017870 ! GATA2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058164 name: APH1A_HUMAN def: "Gamma-secretase subunit APH-1A" [UniProtKB:Q96BI3] synonym: "APH-1a" EXACT [UniProtKB:Q96BI3] synonym: "Aph-1alpha" EXACT [UniProtKB:Q96BI3] synonym: "Presenilin-stabilization factor" EXACT [UniProtKB:Q96BI3] xref: EMBL:AAD34072.1 xref: EMBL:AAH01230.1 xref: EMBL:AAH08732.1 xref: EMBL:AAH09501.1 xref: EMBL:AAH15568.1 xref: EMBL:AAH17699.1 xref: EMBL:AAH20590.1 xref: EMBL:AAM61955.1 xref: EMBL:AAM61956.1 xref: EMBL:AAN63816.1 xref: EMBL:AAQ89310.1 xref: EMBL:BAC11529.1 xref: UniProtKB:Q969R6 xref: UniProtKB:Q96BI3 xref: UniProtKB:Q9BVG0 xref: UniProtKB:Q9Y386 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016987 ! APH1A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000755 ! Notch receptor processing [Term] id: CCO:B0058165 name: AIDA_HUMAN def: "Axin interactor, dorsalization associated protein" [UniProtKB:Q96BJ3] synonym: "Axin interaction partner and dorsalization antagonist" EXACT [UniProtKB:Q96BJ3] xref: EMBL:AAH15535.1 xref: EMBL:AAH43142.1 xref: EMBL:AAH67805.1 xref: EMBL:BAB14281.1 xref: EMBL:BAF82554.1 xref: EMBL:CAH56257.1 xref: EMBL:CAH73929.1 xref: EMBL:CAH73930.1 xref: EMBL:CAI40463.1 xref: EMBL:CAI40464.1 xref: UniProtKB:A8K1F0 xref: UniProtKB:Q49A81 xref: UniProtKB:Q5JRA4 xref: UniProtKB:Q658P1 xref: UniProtKB:Q96BJ3 xref: UniProtKB:Q9H9E8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022030 ! AIDA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002690 ! negative regulation of JNK cascade relationship: transforms_into CCO:B0065494 ! AIDA_HUMAN-Phosphoserine144 [Term] id: CCO:B0058166 name: ARL8A_HUMAN def: "ADP-ribosylation factor-like protein 8A" [UniProtKB:Q96BM9] synonym: "ADP-ribosylation factor-like protein 10B" EXACT [UniProtKB:Q96BM9] synonym: "Novel small G protein indispensable for equal chromosome segregation 2" EXACT [UniProtKB:Q96BM9] xref: EMBL:AAH15408.1 xref: EMBL:BAD23993.1 xref: EMBL:CAI13107.1 xref: UniProtKB:Q96BM9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017041 ! ARL8A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0005781 ! alpha-tubulin binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001017 ! midbody relationship: located_in CCO:C0001340 ! late endosome membrane relationship: located_in CCO:C0002011 ! spindle midzone relationship: participates_in CCO:P0000695 ! chromosome segregation relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058167 name: TAD1L_HUMAN def: "Transcriptional adapter 1-like protein" [UniProtKB:Q96BN2] synonym: "SPT3-associated factor 42" EXACT [UniProtKB:Q96BN2] synonym: "STAF42" EXACT [UniProtKB:Q96BN2] xref: EMBL:AAH15401.1 xref: EMBL:BAF84611.1 xref: EMBL:CAI22772.1 xref: EMBL:CAI23577.1 xref: EMBL:EAW90778.1 xref: UniProtKB:Q96BN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020128 ! TADA1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058168 name: Q96BN9_HUMAN xref: UniProtKB:Q96BN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058169 name: FAM3D_HUMAN def: "Protein FAM3D precursor" [UniProtKB:Q96BQ1] xref: EMBL:AAH15359.1 xref: EMBL:AAQ89040.1 xref: UniProtKB:Q96BQ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017761 ! FAM3D_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0002733 ! negative regulation of insulin secretion [Term] id: CCO:B0058170 name: ZN669_HUMAN def: "Zinc finger protein 669" [UniProtKB:Q96BR6] xref: EMBL:AAH15312.1 xref: EMBL:BAB14166.1 xref: EMBL:CAH70015.1 xref: UniProtKB:Q5VT39 xref: UniProtKB:Q96BR6 xref: UniProtKB:Q9H9Q6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020885 ! ZNF669_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058171 name: ZN775_HUMAN def: "Zinc finger protein 775" [UniProtKB:Q96BV0] xref: EMBL:AAH15152.2 xref: UniProtKB:Q8IY24 xref: UniProtKB:Q96BV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020932 ! ZNF775_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072239 ! ZN775_HUMAN-Phosphothreonine304 [Term] id: CCO:B0058172 name: TBC20_HUMAN def: "TBC1 domain family member 20" [UniProtKB:Q96BZ9] xref: EMBL:AAH14983.1 xref: EMBL:BAB70961.1 xref: EMBL:BAC86808.1 xref: EMBL:BAF84337.1 xref: EMBL:CAI23015.1 xref: EMBL:CAI23048.1 xref: EMBL:EAX10670.1 xref: UniProtKB:A8K6I3 xref: UniProtKB:Q5JWQ7 xref: UniProtKB:Q6ZSY8 xref: UniProtKB:Q96BZ9 xref: UniProtKB:Q96NE1 xref: UniProtKB:Q9BYM7 xref: UniProtKB:Q9H140 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020163 ! TBC1D20_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0058173 name: ZBTB9_HUMAN def: "Zinc finger and BTB domain-containing protein 9" [UniProtKB:Q96C00] xref: EMBL:AAH14978.1 xref: UniProtKB:Q96C00 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020572 ! ZBTB9_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001238 ! retinoid-X receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004420 ! thyroid hormone receptor coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0005774 ! retinoic acid receptor binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071985 ! ZBTB9_HUMAN-Phosphothreonine376 [Term] id: CCO:B0058174 name: Q96C06_HUMAN def: "Interleukin-1 receptor associated-kinase 1 splice variant c" [UniProtKB:Q96C06] synonym: "Interleukin-1 receptor-associated kinase 1" EXACT [UniProtKB:Q96C06] xref: EMBL:AAH14963.1 xref: EMBL:AAY88246.1 xref: UniProtKB:Q96C06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018308 ! IRAK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058175 name: ZN707_HUMAN def: "Zinc finger protein 707" [UniProtKB:Q96C28] xref: EMBL:AAH14894.1 xref: UniProtKB:Q96C28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020910 ! ZNF707_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015386 ! loc286075-mdfi physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058176 name: ZN524_HUMAN def: "Zinc finger protein 524" [UniProtKB:Q96C55] xref: EMBL:AAH07396.2 xref: EMBL:AAH14666.1 xref: EMBL:AAH67748.1 xref: UniProtKB:Q6NW31 xref: UniProtKB:Q96C55 xref: UniProtKB:Q96IL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020795 ! ZNF524_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058177 name: ROP1L_HUMAN def: "Ropporin-1-like protein" [UniProtKB:Q96C74] synonym: "AKAP-associated sperm protein" EXACT [UniProtKB:Q96C74] synonym: "ROPN1-like protein" EXACT [UniProtKB:Q96C74] xref: EMBL:AAG59587.1 xref: EMBL:AAH14607.1 xref: UniProtKB:Q96C74 xref: UniProtKB:Q9BZX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019770 ! ROPN1L_human relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058178 name: Q96C84_HUMAN def: "ZNF215 protein" [UniProtKB:Q96C84] xref: EMBL:AAH14538.1 xref: UniProtKB:Q96C84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020658 ! ZNF215_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058179 name: PP14B_HUMAN def: "Protein phosphatase 1 regulatory subunit 14B" [UniProtKB:Q96C90] synonym: "Phospholipase C beta 3 neighbouring gene protein" EXACT [UniProtKB:Q96C90] xref: EMBL:AAH14522.3 xref: EMBL:AAH94817.1 xref: EMBL:AAP88916.1 xref: UniProtKB:Q504S7 xref: UniProtKB:Q7KZD7 xref: UniProtKB:Q96C90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019472 ! PPP1R14B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: transforms_into CCO:B0069444 ! PP14B_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0069445 ! PP14B_HUMAN-Phosphothreonine57 [Term] id: CCO:B0058180 name: Q96C95_HUMAN def: "MLLT4 protein" [UniProtKB:Q96C95] synonym: "Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog, Drosophila); translocated to, 4" EXACT [UniProtKB:Q96C95] xref: EMBL:AAH14505.1 xref: EMBL:CAI40829.1 xref: EMBL:CAI42815.1 xref: UniProtKB:Q96C95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004036 ! MLLT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058181 name: BIRC7_HUMAN def: "Baculoviral IAP repeat-containing protein 7" [UniProtKB:Q96CA5] synonym: "KIAP" EXACT [UniProtKB:Q96CA5] synonym: "Kidney inhibitor of apoptosis protein" EXACT [UniProtKB:Q96CA5] synonym: "Livin" EXACT [UniProtKB:Q96CA5] synonym: "Melanoma inhibitor of apoptosis protein" EXACT [UniProtKB:Q96CA5] synonym: "ML-IAP" EXACT [UniProtKB:Q96CA5] synonym: "RING finger protein 50" EXACT [UniProtKB:Q96CA5] xref: EMBL:AAG33622.1 xref: EMBL:AAG37878.1 xref: EMBL:AAH14475.1 xref: EMBL:AAQ89194.1 xref: EMBL:AAQ89195.1 xref: EMBL:CAC37337.1 xref: EMBL:CAC37338.1 xref: UniProtKB:Q96CA5 xref: UniProtKB:Q9BQV0 xref: UniProtKB:Q9H2A8 xref: UniProtKB:Q9HAP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017161 ! BIRC7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017872 ! birc7-casp9-3 physical interaction relationship: participates_in CCO:I0017873 ! birc7-prss25-2 physical interaction relationship: participates_in CCO:I0017874 ! birc7-diablo-4 physical interaction relationship: participates_in CCO:I0018027 ! birc7-casp9-2 physical interaction relationship: participates_in CCO:I0018028 ! birc7-diablo-3 physical interaction relationship: participates_in CCO:I0018029 ! birc7-prss25-1 physical interaction relationship: participates_in CCO:I0018185 ! birc7-diablo-2 physical interaction relationship: participates_in CCO:I0018187 ! birc7-casp9-1 physical interaction relationship: participates_in CCO:I0018188 ! birc7-diablo-6 physical interaction relationship: participates_in CCO:I0018491 ! birc7-casp9 physical interaction relationship: participates_in CCO:I0018790 ! birc7-casp3-4 physical interaction relationship: participates_in CCO:I0019246 ! birc7-diablo-7 physical interaction relationship: participates_in CCO:I0019249 ! birc7-casp9-4 physical interaction relationship: participates_in CCO:I0019361 ! birc7-diablo-8 physical interaction relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000774 ! activation of JNK activity [Term] id: CCO:B0058182 name: GP146_HUMAN def: "Probable G-protein coupled receptor 146" [UniProtKB:Q96CH1] synonym: "G-protein coupled receptor PGR8" EXACT [UniProtKB:Q96CH1] xref: EMBL:AAH14241.1 xref: EMBL:AAO85047.1 xref: UniProtKB:Q86SP5 xref: UniProtKB:Q96CH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017971 ! GPR146_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058183 name: EAF2_HUMAN def: "ELL-associated factor 2" [UniProtKB:Q96CJ1] synonym: "Testosterone-regulated apoptosis inducer and tumor suppressor protein" EXACT [UniProtKB:Q96CJ1] xref: EMBL:AAF67627.1 xref: EMBL:AAH14209.1 xref: EMBL:AAL12223.1 xref: EMBL:AAO63811.1 xref: UniProtKB:Q96CJ1 xref: UniProtKB:Q9NZ82 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017651 ! EAF2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064916 ! EAF2_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0064917 ! EAF2_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0064918 ! EAF2_HUMAN-Phosphoserine154 [Term] id: CCO:B0058184 name: ZN653_HUMAN def: "Zinc finger protein 653" [UniProtKB:Q96CK0] synonym: "67 kDa zinc finger protein" EXACT [UniProtKB:Q96CK0] synonym: "Zinc finger protein Zip67" EXACT [UniProtKB:Q96CK0] xref: EMBL:AAH14187.1 xref: EMBL:AAH16816.1 xref: EMBL:AAL66763.1 xref: UniProtKB:Q96AS7 xref: UniProtKB:Q96CK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020876 ! ZNF653_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058185 name: ZN689_HUMAN def: "Zinc finger protein 689" [UniProtKB:Q96CS4] xref: EMBL:AAH14000.1 xref: EMBL:BAC11275.1 xref: EMBL:CAH56363.1 xref: UniProtKB:Q658J5 xref: UniProtKB:Q96CS4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020900 ! ZNF689_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058186 name: ZN501_HUMAN def: "Zinc finger protein 501" [UniProtKB:Q96CX3] synonym: "Zinc finger protein 52" EXACT [UniProtKB:Q96CX3] xref: EMBL:AAH13762.2 xref: EMBL:BAB70773.1 xref: UniProtKB:Q96CX3 xref: UniProtKB:Q96NU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020782 ! ZNF501_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058187 name: Q96CY8_HUMAN def: "MYC associated factor X" [UniProtKB:Q96CY8] xref: EMBL:AAH13669.1 xref: UniProtKB:Q96CY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005033 ! MAX_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015779 ! max-plekhf2 physical interaction relationship: participates_in CCO:I0015826 ! max-mxi1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058188 name: DDT4L_HUMAN def: "DNA-damage-inducible transcript 4-like protein" [UniProtKB:Q96D03] synonym: "HIF-1 responsive protein RTP801-like" EXACT [UniProtKB:Q96D03] synonym: "Protein regulated in development and DNA damage response 2" EXACT [UniProtKB:Q96D03] synonym: "REDD-2" EXACT [UniProtKB:Q96D03] xref: EMBL:AAH13592.1 xref: EMBL:BAC04315.1 xref: EMBL:CAI46176.1 xref: EMBL:EAX06119.1 xref: UniProtKB:Q96D03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017543 ! DDIT4L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015030 ! ddit4l-snrpg physical interaction relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0058189 name: RHES_HUMAN def: "GTP-binding protein Rhes precursor" [UniProtKB:Q96D21] synonym: "Ras homolog enriched in striatum" EXACT [UniProtKB:Q96D21] synonym: "Tumor endothelial marker 2" EXACT [UniProtKB:Q96D21] xref: EMBL:AAG00868.1 xref: EMBL:AAH13419.1 xref: EMBL:CAG30363.1 xref: EMBL:CAI21838.1 xref: UniProtKB:O95520 xref: UniProtKB:Q5THY8 xref: UniProtKB:Q96D21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019712 ! RASD2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069927 ! RHES_HUMAN-Cysteine methyl ester263 [Term] id: CCO:B0058190 name: EID2B_HUMAN def: "EP300-interacting inhibitor of differentiation 2B" [UniProtKB:Q96D98] synonym: "EID-2-like inhibitor of differentiation 3" EXACT [UniProtKB:Q96D98] synonym: "EID-2B" EXACT [UniProtKB:Q96D98] synonym: "EID-3" EXACT [UniProtKB:Q96D98] xref: EMBL:AAH09725.2 xref: EMBL:BAC04743.1 xref: EMBL:EAW56908.1 xref: UniProtKB:Q8N8S0 xref: UniProtKB:Q96D98 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017673 ! EID2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020559 ! flj38944-eef1g physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058191 name: RB39B_HUMAN def: "Ras-related protein Rab-39B" [UniProtKB:Q96DA2] xref: EMBL:AAH09714.1 xref: EMBL:AAL12244.1 xref: EMBL:CAD39120.1 xref: EMBL:CAI41468.1 xref: UniProtKB:Q5JT79 xref: UniProtKB:Q8NEX3 xref: UniProtKB:Q96DA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019639 ! RAB39B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069761 ! RB39B_HUMAN-Cysteine methyl ester213 [Term] id: CCO:B0058192 name: FXYD5_HUMAN def: "FXYD domain-containing ion transport regulator 5 precursor" [UniProtKB:Q96DB9] synonym: "Dysadherin" EXACT [UniProtKB:Q96DB9] xref: EMBL:AAF29077.1 xref: EMBL:AAG09301.1 xref: EMBL:AAH09642.1 xref: EMBL:AAP36007.1 xref: EMBL:AAQ89350.1 xref: EMBL:BAB83766.1 xref: UniProtKB:Q6UW44 xref: UniProtKB:Q96DB9 xref: UniProtKB:Q9HC34 xref: UniProtKB:Q9P039 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017849 ! FXYD5_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002703 ! negative regulation of calcium-dependent cell-cell adhesion [Term] id: CCO:B0058193 name: Q96DH7_HUMAN def: "TBC1D16 protein" [UniProtKB:Q96DH7] xref: EMBL:AAH01525.2 xref: UniProtKB:Q96DH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020161 ! TBC1D16_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0058194 name: WDR67_HUMAN def: "WD repeat-containing protein 67" [UniProtKB:Q96DN5] xref: EMBL:AAH27237.1 xref: EMBL:AAI01725.1 xref: EMBL:AAI11955.1 xref: EMBL:BAB71182.1 xref: UniProtKB:Q2M2J9 xref: UniProtKB:Q3MIR6 xref: UniProtKB:Q8TBP9 xref: UniProtKB:Q96DN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020473 ! WDR67_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0058195 name: SGEF_HUMAN def: "SH3 domain-containing guanine exchange factor" [UniProtKB:Q96DR7] xref: EMBL:AAH16628.1 xref: EMBL:AAH78655.1 xref: EMBL:AAL27001.1 xref: EMBL:AAL27002.1 xref: EMBL:AAS59842.1 xref: EMBL:BAB14159.1 xref: EMBL:BAB14292.1 xref: EMBL:BAD38637.1 xref: EMBL:CAB55918.1 xref: UniProtKB:Q68CL1 xref: UniProtKB:Q6AZ96 xref: UniProtKB:Q6Q8Q8 xref: UniProtKB:Q96AW8 xref: UniProtKB:Q96DR6 xref: UniProtKB:Q96DR7 xref: UniProtKB:Q9H9D7 xref: UniProtKB:Q9H9R2 xref: UniProtKB:Q9UFW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019881 ! SGEF_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0058196 name: M4A6E_HUMAN def: "Membrane-spanning 4-domains subfamily A member 6E" [UniProtKB:Q96DS6] xref: EMBL:AAH34588.1 xref: EMBL:AAH69322.1 xref: EMBL:AAI01784.1 xref: EMBL:AAL07358.1 xref: EMBL:AAL07359.1 xref: EMBL:AAL07360.1 xref: EMBL:AAQ14868.1 xref: UniProtKB:Q3MIL2 xref: UniProtKB:Q8NE56 xref: UniProtKB:Q96DS6 xref: UniProtKB:Q96PG4 xref: UniProtKB:Q96PG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018548 ! MS4A6E_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058197 name: LEG12_HUMAN def: "Galectin-12" [UniProtKB:Q96DT0] synonym: "Galectin-related inhibitor of proliferation" EXACT [UniProtKB:Q96DT0] xref: EMBL:AAF34677.1 xref: EMBL:AAG40863.1 xref: EMBL:AAG40864.1 xref: EMBL:AAH28222.1 xref: EMBL:AAK77328.1 xref: EMBL:AAK77329.1 xref: EMBL:AAK77330.1 xref: EMBL:AAK77331.1 xref: UniProtKB:Q96DS9 xref: UniProtKB:Q96DT0 xref: UniProtKB:Q96PR9 xref: UniProtKB:Q9H258 xref: UniProtKB:Q9H259 xref: UniProtKB:Q9NZ02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018469 ! LGALS12_human relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0004427 ! lactose binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000836 ! induction of apoptosis by intracellular signals [Term] id: CCO:B0058198 name: ZBT10_HUMAN def: "Zinc finger and BTB domain-containing protein 10" [UniProtKB:Q96DT7] synonym: "Zinc finger protein RIN ZF" EXACT [UniProtKB:Q96DT7] xref: EMBL:AAH50061.1 xref: EMBL:BAB71309.1 xref: EMBL:CAC40989.1 xref: EMBL:CAD45447.1 xref: UniProtKB:Q86W96 xref: UniProtKB:Q8IXI9 xref: UniProtKB:Q96DT7 xref: UniProtKB:Q96MH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020543 ! ZBTB10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071954 ! ZBT10_HUMAN-Phosphoserine210 relationship: transforms_into CCO:B0071955 ! ZBT10_HUMAN-Phosphoserine565 relationship: transforms_into CCO:B0071956 ! ZBT10_HUMAN-Phosphoserine647 relationship: transforms_into CCO:B0071957 ! ZBT10_HUMAN-Phosphothreonine721 [Term] id: CCO:B0058199 name: ASB9_HUMAN def: "Ankyrin repeat and SOCS box protein 9" [UniProtKB:Q96DX5] synonym: "ASB-9" EXACT [UniProtKB:Q96DX5] xref: EMBL:AAH13172.1 xref: EMBL:BAA91302.1 xref: EMBL:CAB45706.2 xref: UniProtKB:Q96DX5 xref: UniProtKB:Q9NWS5 xref: UniProtKB:Q9Y4T3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017073 ! ASB9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015193 ! asb9-hif1an physical interaction relationship: participates_in CCO:I0015280 ! asb9-ckb physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058200 name: RAB3C_HUMAN def: "Ras-related protein Rab-3C" [UniProtKB:Q96E17] xref: EMBL:AAH13033.1 xref: EMBL:AAK08968.1 xref: UniProtKB:Q96E17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019595 ! RAB3C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069684 ! RAB3C_HUMAN-Cysteine methyl ester227 [Term] id: CCO:B0058201 name: Q96E53_HUMAN def: "MAX interacting protein 1" [UniProtKB:Q96E53] synonym: "MAX interactor 1" EXACT [UniProtKB:Q96E53] synonym: "MAX interactor 1, isoform CRA_a" EXACT [UniProtKB:Q96E53] xref: EMBL:AAH12907.1 xref: EMBL:AAP35732.1 xref: EMBL:CAI15480.1 xref: EMBL:EAW49565.1 xref: UniProtKB:Q96E53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018686 ! MXI1_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015826 ! max-mxi1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058202 name: KLRG1_HUMAN def: "Killer cell lectin-like receptor subfamily G member 1" [UniProtKB:Q96E93] synonym: "C-type lectin domain family 15 member A" EXACT [UniProtKB:Q96E93] synonym: "ITIM-containing receptor MAFA-L" EXACT [UniProtKB:Q96E93] synonym: "MAFA-like receptor" EXACT [UniProtKB:Q96E93] synonym: "Mast cell function-associated antigen" EXACT [UniProtKB:Q96E93] xref: EMBL:AAC32200.1 xref: EMBL:AAC34731.1 xref: EMBL:AAD03719.1 xref: EMBL:AAH12621.1 xref: EMBL:EAW88594.1 xref: EMBL:EAW88595.1 xref: UniProtKB:O43198 xref: UniProtKB:O75613 xref: UniProtKB:Q96E93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018430 ! KLRG1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015644 ! klrg1-leprotl1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0058203 name: ELP4_HUMAN def: "Elongator complex protein 4" [UniProtKB:Q96EB1] synonym: "hELP4" EXACT [UniProtKB:Q96EB1] synonym: "PAX6 neighbor gene protein" EXACT [UniProtKB:Q96EB1] xref: EMBL:AAH12514.1 xref: EMBL:BAA91212.1 xref: EMBL:CAB66612.1 xref: EMBL:CAC08200.1 xref: EMBL:CAM13056.1 xref: UniProtKB:Q96EB1 xref: UniProtKB:Q9H4E8 xref: UniProtKB:Q9NX11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017698 ! ELP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0065044 ! ELP4_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0065045 ! ELP4_HUMAN-Phosphoserine42 [Term] id: CCO:B0058204 name: SIRT1_HUMAN def: "NAD-dependent deacetylase sirtuin-1" [UniProtKB:Q96EB6] synonym: "EC 3.5.1.-" EXACT [UniProtKB:Q96EB6] synonym: "hSIR2" EXACT [UniProtKB:Q96EB6] synonym: "hSIRT1" EXACT [UniProtKB:Q96EB6] synonym: "SIR2-like protein 1" EXACT [UniProtKB:Q96EB6] xref: EMBL:AAD40849.2 xref: EMBL:AAG38486.1 xref: EMBL:AAH12499.1 xref: EMBL:ABB72675.1 xref: EMBL:CAI16036.1 xref: UniProtKB:Q2XNF6 xref: UniProtKB:Q5JVQ0 xref: UniProtKB:Q96EB6 xref: UniProtKB:Q9GZR9 xref: UniProtKB:Q9Y6F0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019912 ! SIRT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070542 ! SIRT1_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0070543 ! SIRT1_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0070544 ! SIRT1_HUMAN-Phosphothreonine719 [Term] id: CCO:B0058205 name: ZN837_HUMAN def: "Zinc finger protein 837" [UniProtKB:Q96EG3] xref: EMBL:AAH12365.2 xref: UniProtKB:Q96EG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022820 ! ZNF837_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058206 name: TCAL4_HUMAN def: "Transcription elongation factor A protein-like 4" [UniProtKB:Q96EI5] synonym: "TCEA-like protein 4" EXACT [UniProtKB:Q96EI5] synonym: "Transcription elongation factor S-II protein-like 4" EXACT [UniProtKB:Q96EI5] xref: EMBL:AAG44794.1 xref: EMBL:AAH12296.1 xref: EMBL:AAL40909.1 xref: EMBL:BAB15023.1 xref: EMBL:CAI42031.1 xref: UniProtKB:Q8WY12 xref: UniProtKB:Q96EI5 xref: UniProtKB:Q9H2H1 xref: UniProtKB:Q9H775 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020203 ! TCEAL4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071254 ! TCAL4_HUMAN-Phosphotyrosine5 relationship: transforms_into CCO:B0071255 ! TCAL4_HUMAN-Phosphoserine102 [Term] id: CCO:B0058207 name: F120B_HUMAN def: "Constitutive coactivator of peroxisome proliferator-activated receptor gamma" [UniProtKB:Q96EK7] synonym: "Constitutive coactivator of PPAR-gamma" EXACT [UniProtKB:Q96EK7] synonym: "Constitutive coactivator of PPARG" EXACT [UniProtKB:Q96EK7] synonym: "PGCC1" EXACT [UniProtKB:Q96EK7] synonym: "PPARG constitutive coactivator 1" EXACT [UniProtKB:Q96EK7] synonym: "Protein FAM120B" EXACT [UniProtKB:Q96EK7] xref: EMBL:AAH12177.1 xref: EMBL:AAP31032.1 xref: EMBL:ABH09086.1 xref: EMBL:BAB47467.1 xref: EMBL:CAI19554.1 xref: EMBL:CAI23205.1 xref: EMBL:EAW47424.1 xref: UniProtKB:Q86V68 xref: UniProtKB:Q96EK7 xref: UniProtKB:Q96JI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017752 ! FAM120B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0014954 ! kiaa1838-traf2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058208 name: SGF29_HUMAN def: "SAGA-associated factor 29 homolog" [UniProtKB:Q96ES7] synonym: "Coiled-coil domain-containing protein 101" EXACT [UniProtKB:Q96ES7] xref: EMBL:AAH11981.1 xref: EMBL:BAB71340.1 xref: UniProtKB:Q96ES7 xref: UniProtKB:Q96MF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004233 ! CCDC101_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005747 ! loc112869-tada3l physical interaction relationship: participates_in CCO:I0015118 ! krt15-loc112869 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058209 name: NRBF2_HUMAN def: "Nuclear receptor-binding factor 2" [UniProtKB:Q96F24] synonym: "Comodulator of PPAR and RXR" EXACT [UniProtKB:Q96F24] synonym: "NRBF-2" EXACT [UniProtKB:Q96F24] xref: EMBL:AAG44735.1 xref: EMBL:AAH11707.1 xref: EMBL:AAP03081.1 xref: EMBL:AAP03082.1 xref: EMBL:BAB70833.1 xref: EMBL:CAB66591.1 xref: UniProtKB:Q86UR2 xref: UniProtKB:Q96F24 xref: UniProtKB:Q96NP6 xref: UniProtKB:Q9H0S9 xref: UniProtKB:Q9H2I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018864 ! NRBF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068825 ! NRBF2_HUMAN-Phosphoserine120 [Term] id: CCO:B0058210 name: ZN503_HUMAN def: "Zinc finger protein 503" [UniProtKB:Q96F45] xref: EMBL:AAH07494.1 xref: EMBL:AAH11625.1 xref: EMBL:AAH13011.1 xref: EMBL:AAH21165.1 xref: EMBL:BAC03999.1 xref: UniProtKB:Q8NAC5 xref: UniProtKB:Q96E25 xref: UniProtKB:Q96F45 xref: UniProtKB:Q96IJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020784 ! ZNF503_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058211 name: THOC1_HUMAN def: "THO complex subunit 1" [UniProtKB:Q96FV9] synonym: "Nuclear matrix protein p84" EXACT [UniProtKB:Q96FV9] synonym: "Tho1" EXACT [UniProtKB:Q96FV9] xref: EMBL:AAA53571.1 xref: EMBL:AAH10381.1 xref: UniProtKB:Q15219 xref: UniProtKB:Q96FV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020255 ! THOC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071383 ! THOC1_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0071384 ! THOC1_HUMAN-Phosphoserine560 [Term] id: CCO:B0058212 name: Q96G73_HUMAN xref: UniProtKB:Q96G73 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058213 name: P2Y11_HUMAN def: "P2Y purinoceptor 11" [UniProtKB:Q96G91] synonym: "P2Y11" EXACT [UniProtKB:Q96G91] xref: EMBL:AAB88674.1 xref: EMBL:AAH73827.1 xref: EMBL:AAM18130.1 xref: EMBL:AAR18077.1 xref: EMBL:CAC18877.1 xref: EMBL:CAC29362.1 xref: UniProtKB:O43190 xref: UniProtKB:Q96G91 xref: UniProtKB:Q9BYU4 xref: UniProtKB:Q9H170 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019271 ! P2RY11_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0058214 name: ZN274_HUMAN def: "Zinc finger protein 274" [UniProtKB:Q96GC6] synonym: "Zf2" EXACT [UniProtKB:Q96GC6] synonym: "Zinc finger protein HFB101" EXACT [UniProtKB:Q96GC6] synonym: "Zinc finger protein with KRAB and SCAN domains 19" EXACT [UniProtKB:Q96GC6] synonym: "Zinc finger protein zfp2" EXACT [UniProtKB:Q96GC6] xref: EMBL:AAB16810.1 xref: EMBL:AAG24390.1 xref: EMBL:AAG24391.1 xref: EMBL:AAH09763.1 xref: EMBL:BAA88522.1 xref: EMBL:BAA88523.1 xref: UniProtKB:Q8WY37 xref: UniProtKB:Q8WY38 xref: UniProtKB:Q92969 xref: UniProtKB:Q96GC6 xref: UniProtKB:Q9UII0 xref: UniProtKB:Q9UII1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020688 ! ZNF274_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058215 name: SCMH1_HUMAN def: "Polycomb protein SCMH1" [UniProtKB:Q96GD3] synonym: "Sex comb on midleg homolog 1" EXACT [UniProtKB:Q96GD3] xref: EMBL:AAF01150.1 xref: EMBL:AAF01151.1 xref: EMBL:AAH09752.1 xref: EMBL:AAH21252.1 xref: EMBL:CAE45840.1 xref: EMBL:CAG33442.1 xref: EMBL:CAH72242.1 xref: EMBL:CAH72791.1 xref: EMBL:CAH72793.1 xref: EMBL:CAH72794.1 xref: EMBL:CAH72795.1 xref: EMBL:CAH72796.1 xref: EMBL:CAI22109.1 xref: EMBL:CAI22110.1 xref: EMBL:CAI22111.1 xref: EMBL:CAI22112.1 xref: EMBL:CAI22113.1 xref: UniProtKB:Q5VT76 xref: UniProtKB:Q6IAJ4 xref: UniProtKB:Q8WU48 xref: UniProtKB:Q96GD3 xref: UniProtKB:Q9UKM5 xref: UniProtKB:Q9UKM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019847 ! SCMH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017538 ! scmh1-ubqln4 physical interaction relationship: participates_in CCO:I0020126 ! prei3-scmh1 physical interaction relationship: participates_in CCO:I0020360 ! lypla2-scmh1 physical interaction relationship: participates_in CCO:I0020450 ! scmh1-scmh1 physical interaction relationship: participates_in CCO:I0020485 ! tob1-scmh1 physical interaction relationship: participates_in CCO:I0020519 ! q53yb2-scmh1 physical interaction relationship: participates_in CCO:I0020572 ! hk1-scmh1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001125 ! gene silencing relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070348 ! SCMH1_HUMAN-Phosphoserine649 [Term] id: CCO:B0058216 name: ZN799_HUMAN def: "Zinc finger protein 799" [UniProtKB:Q96GE5] synonym: "Zinc finger protein 842" EXACT [UniProtKB:Q96GE5] xref: EMBL:AAH09517.1 xref: UniProtKB:Q96GE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020947 ! ZNF799_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058217 name: Q96GH8_HUMAN xref: UniProtKB:Q96GH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058218 name: Q96GL3_HUMAN def: "IRF3 protein" [UniProtKB:Q96GL3] synonym: "Interferon regulatory factor 3, isoform CRA_b" EXACT [UniProtKB:Q96GL3] xref: EMBL:AAH09395.1 xref: EMBL:EAW52511.1 xref: UniProtKB:Q96GL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018313 ! IRF3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015179 ! prdx1-q96gl3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058219 name: CDA7L_HUMAN def: "Cell division cycle-associated 7-like protein" [UniProtKB:Q96GN5] synonym: "Protein JPO2" EXACT [UniProtKB:Q96GN5] synonym: "Transcription factor RAM2" EXACT [UniProtKB:Q96GN5] xref: EMBL:AAH09352.2 xref: EMBL:AAH14630.2 xref: EMBL:AAH25242.1 xref: EMBL:AAH32576.1 xref: EMBL:AAH39823.1 xref: EMBL:AAO17570.1 xref: EMBL:AAO17571.1 xref: EMBL:BAB14330.1 xref: EMBL:CAB94887.1 xref: UniProtKB:Q6PIL4 xref: UniProtKB:Q86YT0 xref: UniProtKB:Q8IXN5 xref: UniProtKB:Q96C70 xref: UniProtKB:Q96GN5 xref: UniProtKB:Q9H9A2 xref: UniProtKB:Q9NPV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017317 ! CDCA7L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064178 ! CDA7L_HUMAN-Phosphoserine21 relationship: transforms_into CCO:B0064179 ! CDA7L_HUMAN-Phosphothreonine77 relationship: transforms_into CCO:B0064180 ! CDA7L_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0064181 ! CDA7L_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0064182 ! CDA7L_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0064183 ! CDA7L_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0064184 ! CDA7L_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0064185 ! CDA7L_HUMAN-Phosphoserine261 [Term] id: CCO:B0058220 name: ZN486_HUMAN def: "Zinc finger protein 486" [UniProtKB:Q96H40] xref: EMBL:AAH08936.2 xref: UniProtKB:Q96H40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020772 ! ZNF486_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058221 name: SFRP2_HUMAN def: "Secreted frizzled-related protein 2 precursor" [UniProtKB:Q96HF1] synonym: "Frizzled-related protein 2" EXACT [UniProtKB:Q96HF1] synonym: "FRP-2" EXACT [UniProtKB:Q96HF1] synonym: "SARP-1" EXACT [UniProtKB:Q96HF1] synonym: "Secreted apoptosis-related protein 1" EXACT [UniProtKB:Q96HF1] synonym: "sFRP-2" EXACT [UniProtKB:Q96HF1] xref: EMBL:AAB70792.1 xref: EMBL:AAG24923.1 xref: EMBL:AAH08666.1 xref: EMBL:AAQ89360.1 xref: UniProtKB:O14778 xref: UniProtKB:Q96HF1 xref: UniProtKB:Q9HAP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019874 ! SFRP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0070413 ! SFRP2_HUMAN-Phosphoserine289 [Term] id: CCO:B0058222 name: MS4A3_HUMAN def: "Membrane-spanning 4-domains subfamily A member 3" [UniProtKB:Q96HJ5] synonym: "CD20 antigen" EXACT [UniProtKB:Q96HJ5] synonym: "CD20 antigen-like protein" EXACT [UniProtKB:Q96HJ5] synonym: "Hematopoietic-specific transmembrane 4 protein" EXACT [UniProtKB:Q96HJ5] synonym: "HTm4" EXACT [UniProtKB:Q96HJ5] xref: EMBL:AAA62319.1 xref: EMBL:AAH08487.1 xref: EMBL:AAM23312.1 xref: EMBL:AAP14648.1 xref: UniProtKB:Q8NHW2 xref: UniProtKB:Q96HJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018662 ! MS4A3_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058223 name: HES6_HUMAN def: "Transcription cofactor HES-6" [UniProtKB:Q96HZ4] synonym: "C-HAIRY1" EXACT [UniProtKB:Q96HZ4] synonym: "Hairy and enhancer of split 6" EXACT [UniProtKB:Q96HZ4] xref: EMBL:AAH07939.1 xref: EMBL:AAK51634.1 xref: EMBL:AAY24337.1 xref: EMBL:BAA96082.1 xref: EMBL:BAC11368.1 xref: UniProtKB:Q53SN9 xref: UniProtKB:Q8N2J2 xref: UniProtKB:Q96HZ4 xref: UniProtKB:Q96T93 xref: UniProtKB:Q9P2S3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018122 ! HES6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058224 name: FUBP3_HUMAN def: "Far upstream element-binding protein 3" [UniProtKB:Q96I24] synonym: "FUSE-binding protein 3" EXACT [UniProtKB:Q96I24] xref: EMBL:AAC50893.1 xref: EMBL:AAH01325.1 xref: EMBL:AAH07874.1 xref: UniProtKB:Q92946 xref: UniProtKB:Q96I24 xref: UniProtKB:Q9BVB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017846 ! FUBP3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066298 ! FUBP3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0066299 ! FUBP3_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0066300 ! FUBP3_HUMAN-Phosphoserine569 [Term] id: CCO:B0058225 name: ZN625_HUMAN def: "Zinc finger protein 625" [UniProtKB:Q96I27] xref: EMBL:AAH07868.1 xref: UniProtKB:Q96I27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020863 ! ZNF625_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058226 name: KAZD1_HUMAN def: "Kazal-type serine protease inhibitor domain-containing protein 1 precursor" [UniProtKB:Q96I82] xref: EMBL:AAG50291.1 xref: EMBL:AAG50354.1 xref: EMBL:AAH07758.1 xref: EMBL:AAQ89445.1 xref: EMBL:BAD18818.1 xref: EMBL:CAI10937.1 xref: EMBL:CAI10938.1 xref: UniProtKB:Q6ZMB1 xref: UniProtKB:Q96I82 xref: UniProtKB:Q9BQ73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018375 ! KAZALD1_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0058227 name: Q96I83_HUMAN def: "NAB2 protein" [UniProtKB:Q96I83] xref: EMBL:AAH07756.1 xref: UniProtKB:Q96I83 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0058228 name: Q96II5_HUMAN def: "ARAF protein" [UniProtKB:Q96II5] synonym: "Putative uncharacterized protein ARAF" EXACT [UniProtKB:Q96II5] xref: EMBL:AAH07514.1 xref: UniProtKB:A6NIT1 xref: UniProtKB:Q96II5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004087 ! ARAF_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058229 name: TM101_HUMAN def: "Transmembrane protein 101" [UniProtKB:Q96IK0] synonym: "Putative NF-kappa-B-activating protein 130" EXACT [UniProtKB:Q96IK0] xref: EMBL:AAH07438.1 xref: EMBL:BAC77361.1 xref: UniProtKB:Q96IK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020288 ! TMEM101_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058230 name: GMCL1_HUMAN def: "Germ cell-less protein-like 1" [UniProtKB:Q96IK5] xref: EMBL:AAH07420.1 xref: EMBL:BAB14416.1 xref: EMBL:BAB14494.1 xref: EMBL:BAB14796.1 xref: UniProtKB:Q96IK5 xref: UniProtKB:Q9H826 xref: UniProtKB:Q9H8V7 xref: UniProtKB:Q9H927 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017936 ! GMCL1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058231 name: ZN414_HUMAN def: "Zinc finger protein 414" [UniProtKB:Q96IQ9] xref: EMBL:AAH07310.1 xref: EMBL:AAH71937.1 xref: UniProtKB:Q96IQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020737 ! ZNF414_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015109 ! tex11-znf414 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058232 name: RAX2_HUMAN def: "Retina and anterior neural fold homeobox protein 2" [UniProtKB:Q96IS3] synonym: "Q50-type retinal homeobox protein" EXACT [UniProtKB:Q96IS3] synonym: "Retina and anterior neural fold homeobox-like protein 1" EXACT [UniProtKB:Q96IS3] xref: EMBL:AAH07284.1 xref: EMBL:AAH18709.1 xref: EMBL:AAH32512.1 xref: EMBL:AAP41547.1 xref: UniProtKB:Q96IS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019633 ! RAX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058233 name: ZN496_HUMAN def: "Zinc finger protein 496" [UniProtKB:Q96IT1] synonym: "Zinc finger protein with KRAB and SCAN domains 17" EXACT [UniProtKB:Q96IT1] xref: EMBL:AAH07263.1 xref: UniProtKB:Q96IT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020778 ! ZNF496_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015083 ! znf446-znf496 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072137 ! ZN496_HUMAN-Phosphoserine185 [Term] id: CCO:B0058234 name: PAWR_HUMAN def: "PRKC apoptosis WT1 regulator protein" [UniProtKB:Q96IZ0] synonym: "Par-4" EXACT [UniProtKB:Q96IZ0] synonym: "Prostate apoptosis response 4 protein" EXACT [UniProtKB:Q96IZ0] xref: EMBL:AAC24947.1 xref: EMBL:AAH07018.1 xref: EMBL:AAM27453.1 xref: EMBL:AAP43693.1 xref: EMBL:CAG38786.1 xref: UniProtKB:O75796 xref: UniProtKB:Q6FHY9 xref: UniProtKB:Q8N700 xref: UniProtKB:Q96IZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019304 ! PAWR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020515 ! atp5c1-pawr physical interaction relationship: participates_in CCO:I0020659 ! rras2-pawr physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0069126 ! PAWR_HUMAN-Phosphothreonine163 relationship: transforms_into CCO:B0069127 ! PAWR_HUMAN-Phosphotyrosine226 relationship: transforms_into CCO:B0069128 ! PAWR_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0069129 ! PAWR_HUMAN-Phosphothreonine229 relationship: transforms_into CCO:B0069130 ! PAWR_HUMAN-Phosphoserine231 [Term] id: CCO:B0058235 name: ITCH_HUMAN def: "E3 ubiquitin-protein ligase Itchy homolog" [UniProtKB:Q96J02] synonym: "AIP4" EXACT [UniProtKB:Q96J02] synonym: "Atrophin-1-interacting protein 4" EXACT [UniProtKB:Q96J02] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q96J02] synonym: "Itch" EXACT [UniProtKB:Q96J02] synonym: "NAPP1" EXACT [UniProtKB:Q96J02] synonym: "NFE2-associated polypeptide 1" EXACT [UniProtKB:Q96J02] xref: EMBL:AAC04845.1 xref: EMBL:AAH06848.1 xref: EMBL:AAH11571.1 xref: EMBL:AAK39399.1 xref: EMBL:BAB39389.1 xref: EMBL:CAI17959.1 xref: EMBL:CAI21458.1 xref: EMBL:EAW76272.1 xref: UniProtKB:A6NEW4 xref: UniProtKB:O43584 xref: UniProtKB:Q5TEL0 xref: UniProtKB:Q96F66 xref: UniProtKB:Q96J02 xref: UniProtKB:Q9BY75 xref: UniProtKB:Q9H451 xref: UniProtKB:Q9H4U5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018343 ! ITCH_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0067160 ! ITCH_HUMAN-Phosphotyrosine420 [Term] id: CCO:B0058236 name: M4A14_HUMAN def: "Membrane-spanning 4-domains subfamily A member 14" [UniProtKB:Q96JA4] synonym: "Testis development protein NYD-SP21" EXACT [UniProtKB:Q96JA4] xref: EMBL:AAH43485.1 xref: EMBL:AAI07432.1 xref: EMBL:AAK53409.2 xref: EMBL:AAM48587.1 xref: EMBL:AAM48588.1 xref: EMBL:AAV91959.1 xref: EMBL:CAB70719.1 xref: UniProtKB:Q2TVT5 xref: UniProtKB:Q3B7W3 xref: UniProtKB:Q86XH8 xref: UniProtKB:Q96JA4 xref: UniProtKB:Q9NTC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018543 ! MS4A14_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058237 name: COG3_HUMAN def: "Conserved oligomeric Golgi complex subunit 3" [UniProtKB:Q96JB2] synonym: "COG complex subunit 3" EXACT [UniProtKB:Q96JB2] synonym: "Component of oligomeric Golgi complex 3" EXACT [UniProtKB:Q96JB2] synonym: "p94" EXACT [UniProtKB:Q96JB2] synonym: "Vesicle-docking protein SEC34 homolog" EXACT [UniProtKB:Q96JB2] xref: EMBL:AAH38953.1 xref: EMBL:AAK06848.1 xref: EMBL:AAK66974.1 xref: EMBL:CAH72888.1 xref: EMBL:CAH73267.1 xref: UniProtKB:Q5VT70 xref: UniProtKB:Q8IXX4 xref: UniProtKB:Q96JB2 xref: UniProtKB:Q9BZ92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017430 ! COG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002964 ! protein stabilization relationship: transforms_into CCO:B0064447 ! COG3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064448 ! COG3_HUMAN-Phosphoserine533 [Term] id: CCO:B0058238 name: ZN594_HUMAN def: "Zinc finger protein 594" [UniProtKB:Q96JF6] synonym: "HZF18" EXACT [UniProtKB:Q96JF6] synonym: "Zinc finger protein 18" EXACT [UniProtKB:Q96JF6] xref: EMBL:AAS55108.1 xref: EMBL:BAB47500.2 xref: UniProtKB:Q6RFS0 xref: UniProtKB:Q96JF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020844 ! ZNF594_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020500 ! znf594-golga2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058239 name: ZN469_HUMAN def: "Zinc finger protein 469" [UniProtKB:Q96JG9] xref: EMBL:BAB47487.2 xref: UniProtKB:Q96JG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020764 ! ZNF469_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072131 ! ZN469_HUMAN-Phosphothreonine1553 relationship: transforms_into CCO:B0072132 ! ZN469_HUMAN-Phosphoserine3623 relationship: transforms_into CCO:B0072133 ! ZN469_HUMAN-Phosphoserine3624 [Term] id: CCO:B0058240 name: RADIL_HUMAN def: "Ras-associating and dilute domain-containing protein" [UniProtKB:Q96JH8] xref: EMBL:AAH04919.2 xref: EMBL:AAI17318.1 xref: EMBL:AAI26312.1 xref: EMBL:AAS07559.1 xref: EMBL:ABQ59033.1 xref: EMBL:BAA91459.1 xref: EMBL:BAA91543.1 xref: EMBL:BAB47478.1 xref: EMBL:CAB66665.2 xref: EMBL:EAW87301.1 xref: UniProtKB:A5YM49 xref: UniProtKB:Q0VFZ9 xref: UniProtKB:Q75LH3 xref: UniProtKB:Q96JH8 xref: UniProtKB:Q9BSP5 xref: UniProtKB:Q9H0M6 xref: UniProtKB:Q9NW43 xref: UniProtKB:Q9NWC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022555 ! RADIL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015259 ! kiaa1849-pepp2 physical interaction relationship: participates_in CCO:I0015590 ! kiaa1849-magea11 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069706 ! RADIL_HUMAN-Phosphoserine206 [Term] id: CCO:B0058241 name: Q96JJ8_HUMAN def: "KIAA1829 protein" [UniProtKB:Q96JJ8] xref: EMBL:BAB47458.1 xref: UniProtKB:Q96JJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021252 ! KIAA1829_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058242 name: MAML3_HUMAN def: "Mastermind-like protein 3" [UniProtKB:Q96JK9] synonym: "Mam-3" EXACT [UniProtKB:Q96JK9] xref: EMBL:AAI37131.1 xref: EMBL:AAI37132.1 xref: EMBL:BAB47445.1 xref: EMBL:BAG53919.1 xref: EMBL:EAX05107.1 xref: UniProtKB:B2RNU9 xref: UniProtKB:B3KVV7 xref: UniProtKB:Q96JK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018565 ! MAML3_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058243 name: ZN333_HUMAN def: "Zinc finger protein 333" [UniProtKB:Q96JL9] xref: EMBL:AAM15528.1 xref: EMBL:BAB47435.1 xref: UniProtKB:Q8TDL0 xref: UniProtKB:Q96JL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020708 ! ZNF333_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058244 name: ZN462_HUMAN def: "Zinc finger protein 462" [UniProtKB:Q96JM2] xref: EMBL:AAH36884.1 xref: EMBL:BAB47432.2 xref: UniProtKB:Q8N408 xref: UniProtKB:Q96JM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020761 ! ZNF462_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072129 ! ZN462_HUMAN-Phosphotyrosine989 relationship: transforms_into CCO:B0072130 ! ZN462_HUMAN-Phosphoserine1330 [Term] id: CCO:B0058245 name: LMBL3_HUMAN def: "Lethal(3)malignant brain tumor-like 3 protein" [UniProtKB:Q96JM7] synonym: "H-l(3)mbt-like protein" EXACT [UniProtKB:Q96JM7] synonym: "L(3)mbt-like 3 protein" EXACT [UniProtKB:Q96JM7] xref: EMBL:AAH60845.1 xref: EMBL:BAB47427.1 xref: EMBL:CAH73677.1 xref: UniProtKB:Q5VUM9 xref: UniProtKB:Q6P9B5 xref: UniProtKB:Q96JM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018506 ! L3MBTL3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0067690 ! LMBL3_HUMAN-Phosphoserine608 [Term] id: CCO:B0058246 name: LCOR_HUMAN def: "Ligand-dependent corepressor" [UniProtKB:Q96JN0] synonym: "LCoR" EXACT [UniProtKB:Q96JN0] synonym: "Mblk1-related protein 2" EXACT [UniProtKB:Q96JN0] xref: EMBL:AAH53359.1 xref: EMBL:BAB47424.1 xref: EMBL:CAD38921.2 xref: EMBL:CAD91159.1 xref: EMBL:CAD91160.1 xref: EMBL:CAH70915.1 xref: UniProtKB:Q5VW16 xref: UniProtKB:Q7Z723 xref: UniProtKB:Q86T32 xref: UniProtKB:Q86T33 xref: UniProtKB:Q8N3L6 xref: UniProtKB:Q96JN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018464 ! LCOR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067597 ! LCOR_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0067598 ! LCOR_HUMAN-Phosphoserine359 relationship: transforms_into CCO:B0067599 ! LCOR_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0067600 ! LCOR_HUMAN-Phosphoserine367 [Term] id: CCO:B0058247 name: ZFP91_HUMAN def: "Zinc finger protein 91 homolog" [UniProtKB:Q96JP5] synonym: "Zfp-91" EXACT [UniProtKB:Q96JP5] xref: EMBL:AAH51743.1 xref: EMBL:AAL09963.1 xref: EMBL:BAB63373.1 xref: EMBL:BAB63374.1 xref: EMBL:EAW73811.1 xref: UniProtKB:A6NHC4 xref: UniProtKB:Q86V47 xref: UniProtKB:Q96JP4 xref: UniProtKB:Q96JP5 xref: UniProtKB:Q96QA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020595 ! ZFP91_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072018 ! ZFP91_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0072019 ! ZFP91_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0072020 ! ZFP91_HUMAN-Phosphoserine103 relationship: transforms_into CCO:B0072021 ! ZFP91_HUMAN-Phosphothreonine395 [Term] id: CCO:B0058248 name: M4A4A_HUMAN def: "Membrane-spanning 4-domains subfamily A member 4A" [UniProtKB:Q96JQ5] synonym: "CD20 antigen" EXACT [UniProtKB:Q96JQ5] synonym: "CD20 antigen-like 1" EXACT [UniProtKB:Q96JQ5] synonym: "Four-span transmembrane protein 1" EXACT [UniProtKB:Q96JQ5] xref: EMBL:AAF65507.1 xref: EMBL:AAH20648.1 xref: EMBL:AAK37594.1 xref: EMBL:AAL08486.1 xref: EMBL:AAL56220.1 xref: EMBL:BAB18738.1 xref: EMBL:BAB61018.1 xref: UniProtKB:Q8TEZ6 xref: UniProtKB:Q96JQ5 xref: UniProtKB:Q96PG7 xref: UniProtKB:Q9BY18 xref: UniProtKB:Q9H3V3 xref: UniProtKB:Q9P1S3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018545 ! MS4A4A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058249 name: PGBD1_HUMAN def: "PiggyBac transposable element-derived protein 1" [UniProtKB:Q96JS3] synonym: "Cerebral protein 4" EXACT [UniProtKB:Q96JS3] xref: EMBL:AAH69033.1 xref: EMBL:AAI28586.1 xref: EMBL:BAB46919.1 xref: EMBL:BAD97166.1 xref: EMBL:CAD21704.2 xref: UniProtKB:Q53F43 xref: UniProtKB:Q6NTF5 xref: UniProtKB:Q8WWS4 xref: UniProtKB:Q96JS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019375 ! PGBD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069239 ! PGBD1_HUMAN-Phosphoserine351 relationship: transforms_into CCO:B0069240 ! PGBD1_HUMAN-Phosphoserine360 [Term] id: CCO:B0058250 name: Q96K32_HUMAN def: "cDNA FLJ14824 fis, clone OVARC1000771, moderately similar to RAS-RELATED PROTEIN RAB-2" [UniProtKB:Q96K32] xref: EMBL:BAB55326.1 xref: UniProtKB:Q96K32 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058251 name: ZN668_HUMAN def: "Zinc finger protein 668" [UniProtKB:Q96K58] xref: EMBL:AAH21997.1 xref: EMBL:BAB14602.1 xref: EMBL:BAB55084.1 xref: EMBL:BAD92947.1 xref: UniProtKB:Q59EV1 xref: UniProtKB:Q8N669 xref: UniProtKB:Q96K58 xref: UniProtKB:Q9H8L4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020884 ! ZNF668_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058252 name: ZBT45_HUMAN def: "Zinc finger and BTB domain-containing protein 45" [UniProtKB:Q96K62] synonym: "Zinc finger protein 499" EXACT [UniProtKB:Q96K62] xref: EMBL:AAH24738.1 xref: EMBL:BAB55079.1 xref: UniProtKB:Q96K62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020560 ! ZBTB45_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019887 ! znf499-med31 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058253 name: Q96K65_HUMAN def: "cDNA FLJ14478 fis, clone MAMMA1001633, moderately similar to ZINC FINGER PROTEIN 165" [UniProtKB:Q96K65] synonym: "Zinc finger protein 397, isoform CRA_b" EXACT [UniProtKB:Q96K65] xref: EMBL:BAB55075.1 xref: EMBL:EAX01342.1 xref: UniProtKB:Q96K65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020730 ! ZNF397_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058254 name: ZN514_HUMAN def: "Zinc finger protein 514" [UniProtKB:Q96K75] xref: EMBL:AAH74900.1 xref: EMBL:AAH74901.1 xref: EMBL:AAI10525.1 xref: EMBL:AAI10526.1 xref: EMBL:AAX88981.1 xref: EMBL:BAB55064.1 xref: EMBL:CAI46170.1 xref: UniProtKB:Q5JPJ3 xref: UniProtKB:Q96K75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020791 ! ZNF514_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058255 name: GP128_HUMAN def: "Probable G-protein coupled receptor 128 precursor" [UniProtKB:Q96K78] xref: EMBL:AAO27358.1 xref: EMBL:BAB55061.1 xref: UniProtKB:Q86SQ2 xref: UniProtKB:Q96K78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017965 ! GPR128_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0066527 ! GP128_HUMAN-Phosphotyrosine760 [Term] id: CCO:B0058256 name: ZN521_HUMAN def: "Zinc finger protein 521" [UniProtKB:Q96K83] synonym: "Early hematopoietic zinc finger protein" EXACT [UniProtKB:Q96K83] synonym: "LYST-interacting protein 3" EXACT [UniProtKB:Q96K83] xref: EMBL:AAG49442.1 xref: EMBL:AAI13623.1 xref: EMBL:AAI13649.1 xref: EMBL:ABI33104.1 xref: EMBL:BAB13829.1 xref: EMBL:BAB55056.1 xref: EMBL:BAB84872.1 xref: EMBL:CAB56016.1 xref: EMBL:CAD57322.1 xref: UniProtKB:A3QVP7 xref: UniProtKB:Q8IXI0 xref: UniProtKB:Q8TES6 xref: UniProtKB:Q96K83 xref: UniProtKB:Q9C065 xref: UniProtKB:Q9HAL5 xref: UniProtKB:Q9UFK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005962 ! ZNF521_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058257 name: ARL5B_HUMAN def: "ADP-ribosylation factor-like protein 5B" [UniProtKB:Q96KC2] synonym: "ADP-ribosylation factor-like protein 8" EXACT [UniProtKB:Q96KC2] xref: EMBL:AAH24163.1 xref: EMBL:AAM74076.1 xref: EMBL:BAB55011.1 xref: UniProtKB:Q96KC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017038 ! ARL5B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058258 name: DNJC1_HUMAN def: "DnaJ homolog subfamily C member 1" [UniProtKB:Q96KC8] synonym: "DnaJ protein homolog MTJ1" EXACT [UniProtKB:Q96KC8] xref: EMBL:AAI10895.1 xref: EMBL:AAP50497.1 xref: EMBL:BAB15343.1 xref: EMBL:BAB55004.1 xref: EMBL:CAH73412.1 xref: EMBL:CAI13668.1 xref: UniProtKB:Q5VX89 xref: UniProtKB:Q96KC8 xref: UniProtKB:Q9H6B8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017596 ! DNAJC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018574 ! dnajc1-mt1h-1 physical interaction relationship: participates_in CCO:P0002578 ! negative regulation of proteolysis relationship: transforms_into CCO:B0064795 ! DNJC1_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0064796 ! DNJC1_HUMAN-Phosphothreonine365 relationship: transforms_into CCO:B0064797 ! DNJC1_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: transforms_into CCO:B0064799 ! DNJC1_HUMAN-Phosphoserine479 relationship: transforms_into CCO:B0064800 ! DNJC1_HUMAN-Phosphoserine480 [Term] id: CCO:B0058259 name: O10C1_HUMAN def: "Olfactory receptor 10C1" [UniProtKB:Q96KK4] synonym: "Hs6M1-17" EXACT [UniProtKB:Q96KK4] xref: EMBL:AAK95112.1 xref: EMBL:CAB44507.1 xref: UniProtKB:Q96KK4 xref: UniProtKB:Q96R18 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018905 ! OR10C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058260 name: Z512B_HUMAN def: "Zinc finger protein 512B" [UniProtKB:Q96KM6] xref: EMBL:AAI25129.1 xref: EMBL:AAI25130.1 xref: EMBL:BAA86510.1 xref: EMBL:CAC15498.3 xref: EMBL:CAD39181.1 xref: UniProtKB:Q08AK9 xref: UniProtKB:Q96KM6 xref: UniProtKB:Q9ULM4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020528 ! ZNF512B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071941 ! Z512B_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0071942 ! Z512B_HUMAN-Phosphoserine686 [Term] id: CCO:B0058261 name: PKNX2_HUMAN def: "Homeobox protein PKNOX2" [UniProtKB:Q96KN3] synonym: "Homeobox protein PREP-2" EXACT [UniProtKB:Q96KN3] synonym: "PBX/knotted homeobox 2" EXACT [UniProtKB:Q96KN3] xref: EMBL:AAH45626.3 xref: EMBL:BAB83665.1 xref: EMBL:CAD01142.1 xref: EMBL:CAH56146.1 xref: UniProtKB:Q63HL6 xref: UniProtKB:Q86XD1 xref: UniProtKB:Q96KN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019423 ! PKNOX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000324 ! actin monomer binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058262 name: Q96KP3_HUMAN def: "3'5' cyclic nucleotide phosphodiesterase 1B2" [UniProtKB:Q96KP3] synonym: "cDNA FLJ53684, highly similar to Calcium/calmodulin-dependent 3',5'-cyclicnucleotide phosphodiesterase 1B (EC 3.1.4.17)" EXACT [UniProtKB:Q96KP3] synonym: "Phosphodiesterase 1B, calmodulin-dependent, isoform CRA_b" EXACT [UniProtKB:Q96KP3] xref: EMBL:BAG64092.1 xref: EMBL:CAC82207.1 xref: EMBL:EAW96790.1 xref: UniProtKB:Q96KP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021253 ! PDE1B2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058263 name: Q96KW0_HUMAN def: "DJ29K1.3.1 (Novel C2H2 type zinc finger protein (Isoform 1))" [UniProtKB:Q96KW0] xref: EMBL:CAC44640.1 xref: UniProtKB:Q96KW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021254 ! ZNF390_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058264 name: RHOV_HUMAN def: "Rho-related GTP-binding protein RhoV" [UniProtKB:Q96L33] synonym: "CDC42-like GTPase 2" EXACT [UniProtKB:Q96L33] synonym: "GTP-binding protein-like 2" EXACT [UniProtKB:Q96L33] synonym: "Rho GTPase-like protein ARHV" EXACT [UniProtKB:Q96L33] synonym: "Wnt-1 responsive Cdc42 homolog 2" EXACT [UniProtKB:Q96L33] synonym: "WRCH-2" EXACT [UniProtKB:Q96L33] xref: EMBL:AAI05021.1 xref: EMBL:AAI05023.1 xref: EMBL:AAI12946.2 xref: EMBL:AAL17966.1 xref: EMBL:BAB86363.1 xref: EMBL:EAW92459.1 xref: UniProtKB:Q2KHQ5 xref: UniProtKB:Q8TDW6 xref: UniProtKB:Q96L33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019737 ! RHOV_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058265 name: KCNH8_HUMAN def: "Potassium voltage-gated channel subfamily H member 8" [UniProtKB:Q96L42] synonym: "ELK channel 3" EXACT [UniProtKB:Q96L42] synonym: "ELK1" EXACT [UniProtKB:Q96L42] synonym: "ELK3" EXACT [UniProtKB:Q96L42] synonym: "Ether-a-go-go-like potassium channel 3" EXACT [UniProtKB:Q96L42] synonym: "hElk1" EXACT [UniProtKB:Q96L42] synonym: "Voltage-gated potassium channel subunit Kv12.1" EXACT [UniProtKB:Q96L42] xref: EMBL:AAL15429.1 xref: UniProtKB:Q96L42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018397 ! KCNH8_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058266 name: NSD1_HUMAN def: "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific" [UniProtKB:Q96L73] synonym: "Androgen receptor-associated coregulator 267" EXACT [UniProtKB:Q96L73] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q96L73] synonym: "H3-K36-HMTase" EXACT [UniProtKB:Q96L73] synonym: "H4-K20-HMTase" EXACT [UniProtKB:Q96L73] synonym: "Lysine N-methyltransferase 3B" EXACT [UniProtKB:Q96L73] synonym: "NR-binding SET domain-containing protein" EXACT [UniProtKB:Q96L73] synonym: "Nuclear receptor-binding SET domain-containing protein 1" EXACT [UniProtKB:Q96L73] xref: EMBL:AAK92049.1 xref: EMBL:AAL06645.1 xref: EMBL:AAL27991.1 xref: EMBL:AAL40694.1 xref: UniProtKB:Q96L73 xref: UniProtKB:Q96PD8 xref: UniProtKB:Q96RN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018873 ! NSD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068861 ! NSD1_HUMAN-Phosphoserine766 relationship: transforms_into CCO:B0068862 ! NSD1_HUMAN-Phosphoserine2471 [Term] id: CCO:B0058267 name: SNX27_HUMAN def: "Sorting nexin-27" [UniProtKB:Q96L92] xref: EMBL:AAG43127.1 xref: EMBL:AAH12184.1 xref: EMBL:AAH51817.1 xref: EMBL:AAH71825.1 xref: EMBL:AAI00999.1 xref: EMBL:AAI01000.1 xref: EMBL:AAI01001.1 xref: EMBL:AAI01823.1 xref: EMBL:AAI01825.1 xref: EMBL:AAI07863.1 xref: EMBL:AAK97797.1 xref: EMBL:BAE16986.1 xref: EMBL:CAH73501.1 xref: EMBL:CAH73502.1 xref: EMBL:CAH73503.1 xref: EMBL:CAI17164.1 xref: EMBL:CAI17165.1 xref: EMBL:CAI17169.1 xref: UniProtKB:Q32Q36 xref: UniProtKB:Q4AEJ5 xref: UniProtKB:Q5VWB0 xref: UniProtKB:Q5VWB1 xref: UniProtKB:Q5VWB2 xref: UniProtKB:Q6IPP6 xref: UniProtKB:Q86UB1 xref: UniProtKB:Q96D79 xref: UniProtKB:Q96L92 xref: UniProtKB:Q9H3K8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019971 ! SNX27_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058268 name: MRGX4_HUMAN def: "Mas-related G-protein coupled receptor member X4" [UniProtKB:Q96LA9] synonym: "Sensory neuron-specific G-protein coupled receptor 5/6" EXACT [UniProtKB:Q96LA9] xref: EMBL:AAH95509.1 xref: EMBL:AAI07100.1 xref: EMBL:AAI07101.1 xref: EMBL:AAK91807.1 xref: EMBL:AAL86882.1 xref: EMBL:AAL86883.1 xref: UniProtKB:Q3KNU3 xref: UniProtKB:Q3KNU4 xref: UniProtKB:Q502W0 xref: UniProtKB:Q8TDD6 xref: UniProtKB:Q8TDD7 xref: UniProtKB:Q96LA9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018659 ! MRGPRX4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058269 name: MRGX3_HUMAN def: "Mas-related G-protein coupled receptor member X3" [UniProtKB:Q96LB0] synonym: "Sensory neuron-specific G-protein coupled receptor 1/2" EXACT [UniProtKB:Q96LB0] xref: EMBL:AAH67292.1 xref: EMBL:AAK91806.1 xref: EMBL:AAL86878.2 xref: EMBL:AAL86879.2 xref: UniProtKB:Q8TDE0 xref: UniProtKB:Q8TDE1 xref: UniProtKB:Q96LB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018658 ! MRGPRX3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058270 name: MRGX2_HUMAN def: "Mas-related G-protein coupled receptor member X2" [UniProtKB:Q96LB1] xref: EMBL:AAH63450.1 xref: EMBL:AAK91805.1 xref: EMBL:AAW70043.1 xref: EMBL:AAW70044.1 xref: EMBL:AAW70045.1 xref: EMBL:AAW70046.1 xref: EMBL:AAW70047.1 xref: EMBL:AAW70048.1 xref: EMBL:AAW70049.1 xref: EMBL:AAW70050.1 xref: EMBL:AAW70051.1 xref: EMBL:AAW70052.1 xref: EMBL:AAW70053.1 xref: EMBL:AAW70054.1 xref: EMBL:AAW70055.1 xref: EMBL:AAW70056.1 xref: EMBL:AAW70057.1 xref: EMBL:AAW70058.1 xref: EMBL:AAW70059.1 xref: EMBL:AAW70060.1 xref: EMBL:AAW70061.1 xref: EMBL:AAW70062.1 xref: EMBL:AAW70063.1 xref: EMBL:AAW70064.1 xref: EMBL:AAW70065.1 xref: EMBL:AAW70066.1 xref: EMBL:AAW70067.1 xref: EMBL:AAW70068.1 xref: EMBL:AAW70069.1 xref: EMBL:AAW70070.1 xref: EMBL:AAW70071.1 xref: EMBL:AAW70072.1 xref: EMBL:AAW70073.1 xref: EMBL:AAW70074.1 xref: EMBL:AAW70082.1 xref: EMBL:AAW70083.1 xref: EMBL:BAB89339.1 xref: EMBL:BAC06030.1 xref: UniProtKB:Q4QXW4 xref: UniProtKB:Q4QXW7 xref: UniProtKB:Q4QXX0 xref: UniProtKB:Q4QXX2 xref: UniProtKB:Q4QXX3 xref: UniProtKB:Q4QXX4 xref: UniProtKB:Q4QXX6 xref: UniProtKB:Q4QXX7 xref: UniProtKB:Q96LB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018657 ! MRGPRX2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0005746 ! neuropeptide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058271 name: MRGX1_HUMAN def: "Mas-related G-protein coupled receptor member X1" [UniProtKB:Q96LB2] synonym: "Sensory neuron-specific G-protein coupled receptor 3/4" EXACT [UniProtKB:Q96LB2] xref: EMBL:AAH96835.1 xref: EMBL:AAK91804.1 xref: EMBL:AAL86880.2 xref: EMBL:AAL86881.1 xref: EMBL:BAB89341.1 xref: EMBL:BAC06064.1 xref: UniProtKB:Q4V9L2 xref: UniProtKB:Q8TDD8 xref: UniProtKB:Q8TDD9 xref: UniProtKB:Q96LB2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018656 ! MRGPRX1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058272 name: HSFY1_HUMAN def: "Heat shock transcription factor, Y-linked" [UniProtKB:Q96LI6] synonym: "Heat shock transcription factor 2-like protein" EXACT [UniProtKB:Q96LI6] synonym: "HSF2-like" EXACT [UniProtKB:Q96LI6] xref: EMBL:AAH36567.1 xref: EMBL:AAH55414.1 xref: EMBL:AAI17381.1 xref: EMBL:AAI17383.1 xref: EMBL:AAK13478.1 xref: EMBL:AAK13479.1 xref: EMBL:BAB71706.1 xref: EMBL:CAD98806.1 xref: UniProtKB:Q17RC0 xref: UniProtKB:Q7Z4L8 xref: UniProtKB:Q96LI6 xref: UniProtKB:Q9BZA2 xref: UniProtKB:Q9BZA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018167 ! HSFY1_human relationship: encoded_by CCO:G0018168 ! HSFY2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058273 name: Q96LU8_HUMAN def: "cDNA FLJ25054 fis, clone CBL04360" [UniProtKB:Q96LU8] xref: EMBL:BAB71570.1 xref: UniProtKB:Q96LU8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058274 name: Z354B_HUMAN def: "Zinc finger protein 354B" [UniProtKB:Q96LW1] xref: EMBL:AAI04778.1 xref: EMBL:AAI12112.1 xref: EMBL:BAB71556.1 xref: UniProtKB:Q5U5Z4 xref: UniProtKB:Q96LW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020524 ! ZNF354B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058275 name: CC111_HUMAN def: "Coiled-coil domain-containing protein 111" [UniProtKB:Q96LW4] xref: EMBL:AAH64600.1 xref: EMBL:BAB71553.1 xref: EMBL:CAI46079.1 xref: UniProtKB:Q5HYJ9 xref: UniProtKB:Q96LW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017255 ! CCDC111_human relationship: has_function CCO:F0000407 ! DNA primase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000633 ! DNA replication, synthesis of RNA primer [Term] id: CCO:B0058276 name: BINCA_HUMAN def: "Bcl10-interacting CARD protein" [UniProtKB:Q96LW7] synonym: "BinCARD" EXACT [UniProtKB:Q96LW7] xref: EMBL:AAH04500.1 xref: EMBL:AAH38856.1 xref: EMBL:AAH91476.1 xref: EMBL:BAB71550.1 xref: EMBL:CAI95110.1 xref: UniProtKB:Q5BJH8 xref: UniProtKB:Q96LW7 xref: UniProtKB:Q9BSY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017157 ! C9orf89_human relationship: has_function CCO:F0008000 ! CARD domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0002163 ! negative regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058277 name: ZN323_HUMAN def: "Zinc finger protein 323" [UniProtKB:Q96LW9] xref: EMBL:AAM47006.1 xref: EMBL:BAB71548.1 xref: EMBL:CAA17574.2 xref: UniProtKB:Q8WWS5 xref: UniProtKB:Q96LW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020704 ! ZNF323_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058278 name: ZN597_HUMAN def: "Zinc finger protein 597" [UniProtKB:Q96LX8] xref: EMBL:AAH29899.1 xref: EMBL:BAB71538.1 xref: UniProtKB:Q96LX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020847 ! ZNF597_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058279 name: Q96M35_HUMAN def: "cDNA FLJ32854 fis, clone TESTI2003498, moderately similar to TRIPLE FUNCTIONAL DOMAIN PROTEIN" [UniProtKB:Q96M35] xref: EMBL:BAB71477.1 xref: UniProtKB:Q96M35 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0058280 name: YK021_HUMAN def: "Rho GTPase-activating protein FLJ32810" [UniProtKB:Q96M56] synonym: "Rho-type GTPase-activating protein FLJ32810" EXACT [UniProtKB:Q96M56] xref: EMBL:BAB71456.1 xref: UniProtKB:Q96M56 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0071927 ! YK021_HUMAN-Phosphoserine424 [Term] id: CCO:B0058281 name: Q96M80_HUMAN def: "cDNA FLJ32765 fis, clone TESTI2001852, weakly similar to Homo sapiens contactin associated protein (Caspr) mRNA" [UniProtKB:Q96M80] xref: EMBL:BAB71429.1 xref: UniProtKB:Q96M80 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058282 name: FGD4_HUMAN def: "FYVE, RhoGEF and PH domain-containing protein 4" [UniProtKB:Q96M96] synonym: "Actin filament-binding protein frabin" EXACT [UniProtKB:Q96M96] synonym: "FGD1-related F-actin-binding protein" EXACT [UniProtKB:Q96M96] synonym: "Zinc finger FYVE domain-containing protein 6" EXACT [UniProtKB:Q96M96] xref: EMBL:AAQ72372.1 xref: EMBL:BAB71413.1 xref: EMBL:CAD28532.1 xref: UniProtKB:Q6ULS2 xref: UniProtKB:Q8TCP6 xref: UniProtKB:Q96M96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017787 ! FGD4_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004648 ! small GTPase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: participates_in CCO:P0002156 ! regulation of Cdc42 GTPase activity [Term] id: CCO:B0058283 name: DMRTB_HUMAN def: "Doublesex- and mab-3-related transcription factor B1" [UniProtKB:Q96MA1] xref: EMBL:BAB71407.1 xref: EMBL:CAC40654.1 xref: EMBL:CAI22836.1 xref: EMBL:EAX06736.1 xref: UniProtKB:Q96MA1 xref: UniProtKB:Q96SD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017591 ! DMRTB1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058284 name: Q96MB8_HUMAN def: "cDNA FLJ32666 fis, clone TESTI1000096" [UniProtKB:Q96MB8] xref: EMBL:BAB71389.1 xref: UniProtKB:Q96MB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0058285 name: Q96MC1_HUMAN def: "cDNA FLJ32661 fis, clone TESTI1000055, weakly similar to HOMEOBOX PROTEIN SIX1" [UniProtKB:Q96MC1] xref: EMBL:BAB71386.1 xref: UniProtKB:Q96MC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058286 name: Q96ME4_HUMAN def: "cDNA FLJ32471 fis, clone SKNMC2000322, highly similar to Peptidyl-tRNA hydrolase 2, mitochondrial (EC 3.1.1.29)" [UniProtKB:Q96ME4] xref: EMBL:BAB71351.2 xref: UniProtKB:Q96ME4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058287 name: ZN512_HUMAN def: "Zinc finger protein 512" [UniProtKB:Q96ME7] xref: EMBL:BAB47434.1 xref: EMBL:BAB71348.1 xref: UniProtKB:Q96JM0 xref: UniProtKB:Q96ME7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020790 ! ZNF512_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058288 name: STAC3_HUMAN def: "SH3 and cysteine-rich domain-containing protein 3" [UniProtKB:Q96MF2] xref: EMBL:AAH08069.1 xref: EMBL:BAB71343.1 xref: UniProtKB:Q96HU5 xref: UniProtKB:Q96MF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020061 ! STAC3_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058289 name: Q96ML5_HUMAN def: "cDNA FLJ32191 fis, clone PLACE6002151, moderately similar to ZINC FINGER PROTEIN 84" [UniProtKB:Q96ML5] xref: EMBL:BAB71272.1 xref: UniProtKB:Q96ML5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058290 name: Q96MM8_HUMAN def: "cDNA FLJ32136 fis, clone PEBLM2000395, moderately similar to ZINC FINGER PROTEIN 165" [UniProtKB:Q96MM8] xref: EMBL:BAB71258.1 xref: UniProtKB:Q96MM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058291 name: ZN488_HUMAN def: "Zinc finger protein 488" [UniProtKB:Q96MN9] xref: EMBL:AAH51323.1 xref: EMBL:BAB71246.1 xref: EMBL:CAH74044.1 xref: UniProtKB:Q96MN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020773 ! ZNF488_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018962 ! atxn1-znf488 physical interaction relationship: participates_in CCO:I0018987 ! atxn1-znf488-1 physical interaction relationship: participates_in CCO:I0019110 ! atxn1-znf488-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002886 ! positive regulation of oligodendrocyte differentiation [Term] id: CCO:B0058292 name: ZN560_HUMAN def: "Zinc finger protein 560" [UniProtKB:Q96MR9] xref: EMBL:AAI01041.1 xref: EMBL:AAI01042.1 xref: EMBL:AAI01043.1 xref: EMBL:BAB71213.1 xref: UniProtKB:Q495S9 xref: UniProtKB:Q495T1 xref: UniProtKB:Q96MR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020819 ! ZNF560_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058293 name: ZN778_HUMAN def: "Zinc finger protein 778" [UniProtKB:Q96MU6] xref: EMBL:AAI25193.1 xref: EMBL:BAB71183.1 xref: UniProtKB:Q08AG0 xref: UniProtKB:Q96MU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020934 ! ZNF778_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058294 name: KREM1_HUMAN def: "Kremen protein 1 precursor" [UniProtKB:Q96MU8] synonym: "Dickkopf receptor" EXACT [UniProtKB:Q96MU8] synonym: "Kringle domain-containing transmembrane protein 1" EXACT [UniProtKB:Q96MU8] synonym: "Kringle-containing protein marking the eye and the nose" EXACT [UniProtKB:Q96MU8] xref: EMBL:AAH63787.1 xref: EMBL:BAB40969.1 xref: EMBL:BAB71180.1 xref: EMBL:CAM25375.1 xref: EMBL:CAM25378.1 xref: EMBL:CAQ07689.1 xref: EMBL:CAQ07690.1 xref: EMBL:CAQ08609.1 xref: EMBL:CAQ08610.1 xref: EMBL:EAW59774.1 xref: UniProtKB:B0QY46 xref: UniProtKB:B0QY47 xref: UniProtKB:B1AJR5 xref: UniProtKB:Q5TIB9 xref: UniProtKB:Q6P3X6 xref: UniProtKB:Q96MU8 xref: UniProtKB:Q9BY70 xref: UniProtKB:Q9UGS5 xref: UniProtKB:Q9UGU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018437 ! KREMEN1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058295 name: TIGD1_HUMAN def: "Tigger transposable element-derived protein 1" [UniProtKB:Q96MW7] xref: EMBL:AAH35143.2 xref: EMBL:AAH63500.2 xref: EMBL:AAY24104.1 xref: EMBL:BAB71153.1 xref: UniProtKB:Q6P4D2 xref: UniProtKB:Q6PIF9 xref: UniProtKB:Q96MW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020266 ! TIGD1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058296 name: ZNF48_HUMAN def: "Zinc finger protein 48" [UniProtKB:Q96MX3] synonym: "Zinc finger protein 553" EXACT [UniProtKB:Q96MX3] xref: EMBL:AAA61316.1 xref: EMBL:AAH07393.2 xref: EMBL:AAH41388.1 xref: EMBL:BAB71146.1 xref: EMBL:CAH10657.1 xref: UniProtKB:Q15920 xref: UniProtKB:Q4G0R3 xref: UniProtKB:Q69YP3 xref: UniProtKB:Q96IL9 xref: UniProtKB:Q96MX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022826 ! ZNF48_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058297 name: Q96N14_HUMAN xref: UniProtKB:Q96N14 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058298 name: ZN681_HUMAN def: "Zinc finger protein 681" [UniProtKB:Q96N22] xref: EMBL:BAB71090.1 xref: UniProtKB:Q96N22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020895 ! ZNF681_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058299 name: ZN578_HUMAN def: "Zinc finger protein 578" [UniProtKB:Q96N58] xref: EMBL:BAB71051.1 xref: UniProtKB:Q96N58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020835 ! ZNF578_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058300 name: DOCK7_HUMAN def: "Dedicator of cytokinesis protein 7" [UniProtKB:Q96N67] xref: EMBL:AAH16392.1 xref: EMBL:AAZ38451.1 xref: EMBL:AAZ38452.1 xref: EMBL:ABC33725.1 xref: EMBL:ABC68221.1 xref: EMBL:BAB21862.1 xref: EMBL:BAB70933.1 xref: EMBL:BAB71042.1 xref: EMBL:BAC86032.1 xref: EMBL:CAI13104.1 xref: EMBL:CAI13105.1 xref: EMBL:CAI22995.1 xref: UniProtKB:Q00M63 xref: UniProtKB:Q2PPY7 xref: UniProtKB:Q45RE8 xref: UniProtKB:Q45RE9 xref: UniProtKB:Q5T1B9 xref: UniProtKB:Q5T1C0 xref: UniProtKB:Q6ZV32 xref: UniProtKB:Q8TB82 xref: UniProtKB:Q96N67 xref: UniProtKB:Q96NG6 xref: UniProtKB:Q9C092 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017600 ! DOCK7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001690 ! activation of Rac GTPase activity relationship: participates_in CCO:P0001795 ! positive regulation of peptidyl-serine phosphorylation relationship: transforms_into CCO:B0064820 ! DOCK7_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0064821 ! DOCK7_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0064822 ! DOCK7_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0064823 ! DOCK7_HUMAN-Phosphoserine882 relationship: transforms_into CCO:B0064824 ! DOCK7_HUMAN-Phosphoserine888 relationship: transforms_into CCO:B0064825 ! DOCK7_HUMAN-Phosphoserine900 relationship: transforms_into CCO:B0064826 ! DOCK7_HUMAN-Phosphothreonine907 relationship: transforms_into CCO:B0064827 ! DOCK7_HUMAN-Phosphoserine910 relationship: transforms_into CCO:B0064828 ! DOCK7_HUMAN-Phosphoserine964 relationship: transforms_into CCO:B0064829 ! DOCK7_HUMAN-Phosphothreonine966 relationship: transforms_into CCO:B0064830 ! DOCK7_HUMAN-Phosphoserine1383 relationship: transforms_into CCO:B0064831 ! DOCK7_HUMAN-Phosphoserine1432 [Term] id: CCO:B0058301 name: ZN641_HUMAN def: "Zinc finger protein 641" [UniProtKB:Q96N77] xref: EMBL:AAH18090.2 xref: EMBL:AAW28082.1 xref: EMBL:BAB71031.1 xref: EMBL:CAD28468.1 xref: UniProtKB:Q8TCQ7 xref: UniProtKB:Q8WVE1 xref: UniProtKB:Q96N77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020869 ! ZNF641_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058302 name: ZN396_HUMAN def: "Zinc finger protein 396" [UniProtKB:Q96N95] synonym: "Zinc finger and SCAN domain-containing protein 14" EXACT [UniProtKB:Q96N95] xref: EMBL:AAM09559.3 xref: EMBL:AAM95992.1 xref: EMBL:BAB71010.1 xref: UniProtKB:Q8NF98 xref: UniProtKB:Q8TD80 xref: UniProtKB:Q96N95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020729 ! ZNF396_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0058303 name: ZN583_HUMAN def: "Zinc finger protein 583" [UniProtKB:Q96ND8] synonym: "Zinc finger protein L3-5" EXACT [UniProtKB:Q96ND8] xref: EMBL:AAB81088.1 xref: EMBL:AAI11773.1 xref: EMBL:BAB70964.1 xref: UniProtKB:O14850 xref: UniProtKB:Q2NKK3 xref: UniProtKB:Q96ND8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020837 ! ZNF583_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058304 name: ZN558_HUMAN def: "Zinc finger protein 558" [UniProtKB:Q96NG5] xref: EMBL:AAH64356.1 xref: EMBL:BAB70934.1 xref: UniProtKB:Q96NG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020817 ! ZNF558_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017314 ! exosc5-znf558 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058305 name: CF170_HUMAN def: "Transmembrane protein C6orf170" [UniProtKB:Q96NH3] xref: EMBL:BAB70925.1 xref: EMBL:BAC03694.1 xref: EMBL:BAC86152.1 xref: EMBL:BAD18591.1 xref: EMBL:CAI16051.2 xref: EMBL:CAI20000.2 xref: EMBL:CAM16339.1 xref: EMBL:CAM17813.1 xref: EMBL:CAM28224.1 xref: UniProtKB:Q5SZM6 xref: UniProtKB:Q6ZMY4 xref: UniProtKB:Q6ZUR7 xref: UniProtKB:Q8NB47 xref: UniProtKB:Q96NH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017338 ! C6orf170_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0058306 name: ZN570_HUMAN def: "Zinc finger protein 570" [UniProtKB:Q96NI8] xref: EMBL:BAB70908.1 xref: UniProtKB:Q96NI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020827 ! ZNF570_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058307 name: ZFP3_HUMAN def: "Zinc finger protein 3 homolog" [UniProtKB:Q96NJ6] synonym: "Zfp-3" EXACT [UniProtKB:Q96NJ6] xref: EMBL:BAB70898.1 xref: UniProtKB:Q96NJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020590 ! ZFP3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058308 name: NDF6_HUMAN def: "Neurogenic differentiation factor 6" [UniProtKB:Q96NK8] synonym: "NeuroD6" EXACT [UniProtKB:Q96NK8] synonym: "Protein atonal homolog 2" EXACT [UniProtKB:Q96NK8] xref: EMBL:AAG43167.1 xref: EMBL:BAB70885.1 xref: UniProtKB:Q96NK8 xref: UniProtKB:Q9H3H6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018737 ! NEUROD6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058309 name: ZN599_HUMAN def: "Zinc finger protein 599" [UniProtKB:Q96NL3] xref: EMBL:AAH44615.1 xref: EMBL:AAH92428.1 xref: EMBL:BAB70879.1 xref: UniProtKB:Q569K0 xref: UniProtKB:Q5PRG1 xref: UniProtKB:Q96NL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020848 ! ZNF599_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058310 name: TOX2_HUMAN def: "TOX high mobility group box family member 2" [UniProtKB:Q96NM4] synonym: "GCX-1" EXACT [UniProtKB:Q96NM4] synonym: "Granulosa cell HMG box protein 1" EXACT [UniProtKB:Q96NM4] xref: EMBL:BAB70860.1 xref: EMBL:CAI21559.1 xref: EMBL:CAI21560.1 xref: EMBL:CAI21561.1 xref: EMBL:CAI42198.1 xref: EMBL:CAI42200.1 xref: EMBL:CAI42201.1 xref: UniProtKB:Q5TE33 xref: UniProtKB:Q5TE34 xref: UniProtKB:Q5TE35 xref: UniProtKB:Q96IC9 xref: UniProtKB:Q96NM4 xref: UniProtKB:Q9BQN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020325 ! TOX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058311 name: AIFM3_HUMAN def: "Apoptosis-inducing factor 3" [UniProtKB:Q96NN9] synonym: "Apoptosis-inducing factor-like protein" EXACT [UniProtKB:Q96NN9] synonym: "EC 1.-.-.-" EXACT [UniProtKB:Q96NN9] xref: EMBL:AAH32485.1 xref: EMBL:BAB70841.1 xref: EMBL:BAC04434.1 xref: EMBL:BAC86750.1 xref: EMBL:CAG30228.1 xref: UniProtKB:Q6ZT44 xref: UniProtKB:Q8N1V3 xref: UniProtKB:Q8N5E0 xref: UniProtKB:Q96NN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016937 ! AIFM3_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008139 ! 2 iron, 2 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000842 ! caspase activation via cytochrome c [Term] id: CCO:B0058312 name: ASB16_HUMAN def: "Ankyrin repeat and SOCS box protein 16" [UniProtKB:Q96NS5] synonym: "ASB-16" EXACT [UniProtKB:Q96NS5] xref: EMBL:AAH75088.1 xref: EMBL:AAL57353.1 xref: EMBL:BAB70800.1 xref: UniProtKB:Q8WXK0 xref: UniProtKB:Q96NS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017062 ! ASB16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058313 name: CNT3B_HUMAN def: "Contactin-associated protein-like 3B precursor" [UniProtKB:Q96NU0] synonym: "Cell recognition molecule Caspr3b" EXACT [UniProtKB:Q96NU0] xref: EMBL:BAB14861.1 xref: EMBL:BAB70782.1 xref: EMBL:CAI12626.1 xref: EMBL:CAI12627.1 xref: EMBL:CAI12628.1 xref: EMBL:CAI16324.1 xref: EMBL:CAI16325.1 xref: EMBL:CAI16326.1 xref: EMBL:CAI94998.1 xref: EMBL:CAI95046.1 xref: EMBL:CAI95047.1 xref: EMBL:CAI95048.1 xref: EMBL:CAI95050.1 xref: EMBL:CAI95288.1 xref: EMBL:CAI95321.1 xref: UniProtKB:B1B0V7 xref: UniProtKB:B1B0V8 xref: UniProtKB:B1B0V9 xref: UniProtKB:B1B0W0 xref: UniProtKB:B1B0X8 xref: UniProtKB:B1B162 xref: UniProtKB:Q4VXF0 xref: UniProtKB:Q96NU0 xref: UniProtKB:Q9H7W3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017412 ! CNTNAP3B_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058314 name: DACH2_HUMAN def: "Dachshund homolog 2" [UniProtKB:Q96NX9] synonym: "Dach2" EXACT [UniProtKB:Q96NX9] xref: EMBL:AAL26561.1 xref: EMBL:BAB71054.1 xref: EMBL:BAC03761.1 xref: EMBL:CAD39116.1 xref: UniProtKB:Q8NAY3 xref: UniProtKB:Q8ND17 xref: UniProtKB:Q96N55 xref: UniProtKB:Q96NX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017518 ! DACH2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058315 name: FOXN4_HUMAN def: "Forkhead box protein N4" [UniProtKB:Q96NZ1] xref: EMBL:AAL23949.1 xref: EMBL:AAL23950.1 xref: EMBL:BAD18661.1 xref: UniProtKB:Q6ZMR4 xref: UniProtKB:Q96NZ0 xref: UniProtKB:Q96NZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017825 ! FOXN4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058316 name: NALP3_HUMAN def: "NACHT, LRR and PYD domains-containing protein 3" [UniProtKB:Q96P20] synonym: "Angiotensin/vasopressin receptor AII/AVP-like" EXACT [UniProtKB:Q96P20] synonym: "Cold autoinflammatory syndrome 1 protein" EXACT [UniProtKB:Q96P20] synonym: "Cryopyrin" EXACT [UniProtKB:Q96P20] synonym: "PYRIN-containing APAF1-like protein 1" EXACT [UniProtKB:Q96P20] xref: EMBL:AAC39910.1 xref: EMBL:AAI17212.1 xref: EMBL:AAL12497.1 xref: EMBL:AAL12498.1 xref: EMBL:AAL14640.2 xref: EMBL:AAL33908.1 xref: EMBL:AAL33911.1 xref: EMBL:AAL65136.1 xref: EMBL:AAL78632.1 xref: EMBL:AAM14669.1 xref: EMBL:AAQ98889.1 xref: EMBL:BAD92128.1 xref: EMBL:CAI17153.1 xref: EMBL:CAI17154.1 xref: EMBL:CAI17155.1 xref: UniProtKB:O75434 xref: UniProtKB:Q17RS2 xref: UniProtKB:Q59H68 xref: UniProtKB:Q5JQS8 xref: UniProtKB:Q5JQS9 xref: UniProtKB:Q6TG35 xref: UniProtKB:Q8TCW0 xref: UniProtKB:Q8TEU9 xref: UniProtKB:Q8WXH9 xref: UniProtKB:Q96P20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018712 ! NLRP3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005721 ! peptidoglycan binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001541 ! negative regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0002178 ! positive regulation of caspase activity [Term] id: CCO:B0058317 name: CENG3_HUMAN def: "Centaurin-gamma-3" [UniProtKB:Q96P47] synonym: "AGAP-3" EXACT [UniProtKB:Q96P47] synonym: "ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3" EXACT [UniProtKB:Q96P47] synonym: "CRAG" EXACT [UniProtKB:Q96P47] synonym: "CRAM-associated GTPase" EXACT [UniProtKB:Q96P47] synonym: "MR1-interacting protein" EXACT [UniProtKB:Q96P47] synonym: "MRIP-1" EXACT [UniProtKB:Q96P47] xref: EMBL:AAK48932.2 xref: EMBL:AAL04173.1 xref: EMBL:BAD93018.1 xref: UniProtKB:Q59EN0 xref: UniProtKB:Q96P47 xref: UniProtKB:Q96RK3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017332 ! CENTG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0064272 ! CENG3_HUMAN-Phosphothreonine324 relationship: transforms_into CCO:B0064273 ! CENG3_HUMAN-Phosphothreonine326 relationship: transforms_into CCO:B0064274 ! CENG3_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0064275 ! CENG3_HUMAN-Phosphoserine443 [Term] id: CCO:B0058318 name: CENB5_HUMAN def: "Centaurin-beta-5" [UniProtKB:Q96P50] synonym: "Cnt-b5" EXACT [UniProtKB:Q96P50] xref: EMBL:AAH04874.2 xref: EMBL:AAL04165.1 xref: EMBL:BAB21807.1 xref: UniProtKB:Q96P50 xref: UniProtKB:Q9BSR9 xref: UniProtKB:Q9C0E7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008671 ! CENTB5_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020041 ! itgb3bp-centb5 physical interaction relationship: participates_in CCO:I0020678 ! tmem22-centb5 physical interaction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0058319 name: Q96P62_HUMAN def: "Protein kinase A type 1a regulatory subunit" [UniProtKB:Q96P62] xref: EMBL:AAL05860.1 xref: UniProtKB:Q96P62 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004930 ! PRKAR1A_human relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058320 name: QRFPR_HUMAN def: "Orexigenic neuropeptide QRFP receptor" [UniProtKB:Q96P65] synonym: "AQ27" EXACT [UniProtKB:Q96P65] synonym: "G-protein coupled receptor 103" EXACT [UniProtKB:Q96P65] synonym: "SP9155" EXACT [UniProtKB:Q96P65] xref: EMBL:AAL26488.1 xref: EMBL:BAC98938.1 xref: UniProtKB:Q96P65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019568 ! GPR103_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058321 name: GP101_HUMAN def: "Probable G-protein coupled receptor 101" [UniProtKB:Q96P66] xref: EMBL:AAH69439.1 xref: EMBL:AAL26486.1 xref: EMBL:BAB89301.1 xref: EMBL:BAC06152.1 xref: UniProtKB:Q8NG93 xref: UniProtKB:Q96P66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017953 ! GPR101_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058322 name: GPR82_HUMAN def: "Probable G-protein coupled receptor 82" [UniProtKB:Q96P67] xref: EMBL:AAH70180.1 xref: EMBL:AAL26482.1 xref: EMBL:BAB89308.1 xref: EMBL:BAC06150.1 xref: UniProtKB:Q96P67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018034 ! GPR82_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058323 name: OXGR1_HUMAN def: "2-oxoglutarate receptor 1" [UniProtKB:Q96P68] synonym: "Alpha-ketoglutarate receptor 1" EXACT [UniProtKB:Q96P68] synonym: "G-protein coupled receptor 80" EXACT [UniProtKB:Q96P68] synonym: "G-protein coupled receptor 99" EXACT [UniProtKB:Q96P68] synonym: "P2Y purinoceptor 15" EXACT [UniProtKB:Q96P68] synonym: "P2Y-like GPCR" EXACT [UniProtKB:Q96P68] synonym: "P2Y-like nucleotide receptor" EXACT [UniProtKB:Q96P68] xref: EMBL:AAI03882.1 xref: EMBL:AAI03883.1 xref: EMBL:AAI03884.1 xref: EMBL:AAL26480.1 xref: EMBL:AAM76912.1 xref: EMBL:BAB89311.1 xref: EMBL:BAC06095.1 xref: EMBL:CAC83857.1 xref: EMBL:CAI16508.1 xref: UniProtKB:Q5T5A7 xref: UniProtKB:Q86TL1 xref: UniProtKB:Q96P68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019254 ! OXGR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058324 name: GPR78_HUMAN def: "Probable G-protein coupled receptor 78" [UniProtKB:Q96P69] xref: EMBL:AAH57778.1 xref: EMBL:AAH69343.1 xref: EMBL:AAH69813.1 xref: EMBL:AAL26479.1 xref: EMBL:AAQ89465.1 xref: EMBL:BAC05898.1 xref: UniProtKB:Q8NGV3 xref: UniProtKB:Q96P69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018032 ! GPR78_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058325 name: NECA3_HUMAN def: "N-terminal EF-hand calcium-binding protein 3" [UniProtKB:Q96P71] synonym: "Amyloid beta A4 protein-binding family A member 2-binding protein" EXACT [UniProtKB:Q96P71] synonym: "Nek2-interacting protein 1" EXACT [UniProtKB:Q96P71] synonym: "Neuronal calcium-binding protein 3" EXACT [UniProtKB:Q96P71] synonym: "X11L-binding protein 51" EXACT [UniProtKB:Q96P71] xref: EMBL:AAG28415.1 xref: EMBL:AAH47673.1 xref: EMBL:AAL01118.1 xref: EMBL:BAB14649.1 xref: EMBL:BAB16413.1 xref: EMBL:CAI22127.1 xref: EMBL:CAI22128.1 xref: UniProtKB:Q5JWF6 xref: UniProtKB:Q5JWF7 xref: UniProtKB:Q86VV1 xref: UniProtKB:Q96P71 xref: UniProtKB:Q9H433 xref: UniProtKB:Q9H8G8 xref: UniProtKB:Q9HBW7 xref: UniProtKB:Q9HCQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018748 ! NECAB3_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000019 ! Golgi cis cisterna relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: participates_in CCO:P0002132 ! regulation of amyloid precursor protein biosynthetic process [Term] id: CCO:B0058326 name: GNRR2_HUMAN def: "Putative gonadotropin-releasing hormone II receptor" [UniProtKB:Q96P88] synonym: "GnRH-II-R" EXACT [UniProtKB:Q96P88] synonym: "Type II GnRH receptor" EXACT [UniProtKB:Q96P88] xref: EMBL:AAL27000.1 xref: EMBL:AAL89821.1 xref: UniProtKB:Q8TCX8 xref: UniProtKB:Q96P88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017948 ! GNRHR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001309 ! gonadotropin-releasing hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058327 name: Q96PA4_HUMAN def: "Beta-glucan receptor isoform H" [UniProtKB:Q96PA4] synonym: "C-type lectin domain family 7, member A, isoform CRA_j" EXACT [UniProtKB:Q96PA4] xref: EMBL:AAL11718.1 xref: EMBL:EAW96154.1 xref: UniProtKB:Q96PA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021255 ! BGR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001838 ! pattern recognition receptor activity relationship: has_function CCO:F0005647 ! MHC protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000862 ! carbohydrate mediated signaling [Term] id: CCO:B0058328 name: DCBD2_HUMAN def: "Discoidin, CUB and LCCL domain-containing protein 2 precursor" [UniProtKB:Q96PD2] synonym: "CUB, LCCL and coagulation factor V/VIII-homology domains protein 1" EXACT [UniProtKB:Q96PD2] synonym: "Endothelial and smooth muscle cell-derived neuropilin-like protein" EXACT [UniProtKB:Q96PD2] xref: EMBL:AAH29658.1 xref: EMBL:AAL30178.1 xref: EMBL:BAB91138.1 xref: UniProtKB:Q8N6M4 xref: UniProtKB:Q8TDX2 xref: UniProtKB:Q96PD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017529 ! DCBLD2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001281 ! intracellular receptor-mediated signaling pathway relationship: transforms_into CCO:B0064646 ! DCBD2_HUMAN-Phosphoserine606 relationship: transforms_into CCO:B0064647 ! DCBD2_HUMAN-Phosphotyrosine750 [Term] id: CCO:B0058329 name: GP124_HUMAN def: "Probable G-protein coupled receptor 124 precursor" [UniProtKB:Q96PE1] synonym: "Tumor endothelial marker 5" EXACT [UniProtKB:Q96PE1] xref: EMBL:AAL11992.1 xref: EMBL:AAO27354.1 xref: EMBL:BAA96055.2 xref: EMBL:BAB55022.1 xref: EMBL:BAB84925.1 xref: EMBL:CAB53694.1 xref: EMBL:CAD38629.1 xref: UniProtKB:Q8N3R1 xref: UniProtKB:Q8TEM3 xref: UniProtKB:Q96KB2 xref: UniProtKB:Q96PE1 xref: UniProtKB:Q9P1Z7 xref: UniProtKB:Q9UFY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017963 ! GPR124_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0058330 name: ARHGH_HUMAN def: "Rho guanine nucleotide exchange factor 17" [UniProtKB:Q96PE2] synonym: "164 kDa Rho-specific guanine-nucleotide exchange factor" EXACT [UniProtKB:Q96PE2] synonym: "p164-RhoGEF" EXACT [UniProtKB:Q96PE2] synonym: "p164RhoGEF" EXACT [UniProtKB:Q96PE2] synonym: "Tumor endothelial marker 4" EXACT [UniProtKB:Q96PE2] xref: EMBL:AAH50031.1 xref: EMBL:AAL11991.1 xref: EMBL:BAA20795.2 xref: EMBL:BAC11025.1 xref: UniProtKB:Q86XU2 xref: UniProtKB:Q8N2S0 xref: UniProtKB:Q96PE2 xref: UniProtKB:Q9Y4G3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017023 ! ARHGEF17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0063561 ! ARHGH_HUMAN-Phosphoserine138 [Term] id: CCO:B0058331 name: INP4A_HUMAN def: "Type I inositol-3,4-bisphosphate 4-phosphatase" [UniProtKB:Q96PE3] synonym: "EC 3.1.3.66" EXACT [UniProtKB:Q96PE3] synonym: "Inositol polyphosphate 4-phosphatase type I" EXACT [UniProtKB:Q96PE3] xref: EMBL:AAB01068.1 xref: EMBL:AAB72150.1 xref: EMBL:AAH28361.1 xref: EMBL:AAK58870.1 xref: EMBL:AAX93230.1 xref: UniProtKB:O15326 xref: UniProtKB:Q13187 xref: UniProtKB:Q53TD8 xref: UniProtKB:Q8TC02 xref: UniProtKB:Q96PE3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018288 ! INPP4A_human relationship: has_function CCO:F0003121 ! phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058332 name: ZIM3_HUMAN def: "Zinc finger imprinted 3" [UniProtKB:Q96PE6] xref: EMBL:AAI14447.1 xref: EMBL:AAI14504.1 xref: EMBL:AAL11635.1 xref: UniProtKB:Q14CA6 xref: UniProtKB:Q96PE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020607 ! ZIM3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058333 name: M4A4E_HUMAN def: "Putative membrane-spanning 4-domains subfamily A member 4E" [UniProtKB:Q96PG1] xref: EMBL:AAL07363.1 xref: EMBL:BAE46883.1 xref: EMBL:BAE46884.1 xref: EMBL:BAE46885.1 xref: EMBL:BAE46886.1 xref: UniProtKB:Q3C1W1 xref: UniProtKB:Q3C1W3 xref: UniProtKB:Q3C1W4 xref: UniProtKB:Q96PG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018546 ! MS4A4E_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058334 name: M4A10_HUMAN def: "Membrane-spanning 4-domains subfamily A member 10" [UniProtKB:Q96PG2] xref: EMBL:AAL07361.1 xref: EMBL:AAL07362.1 xref: EMBL:BAC85498.1 xref: UniProtKB:Q96PG2 xref: UniProtKB:Q96PG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018540 ! MS4A10_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058335 name: NOX5_HUMAN def: "NADPH oxidase 5" [UniProtKB:Q96PH1] synonym: "EC 1.6.3.-" EXACT [UniProtKB:Q96PH1] xref: EMBL:AAG33638.1 xref: EMBL:AAK57193.1 xref: EMBL:AAK57194.1 xref: EMBL:AAK57338.1 xref: EMBL:AAK57339.1 xref: EMBL:ABC40743.1 xref: EMBL:BAB15319.1 xref: EMBL:BAB84884.1 xref: EMBL:BAB84897.1 xref: UniProtKB:Q8TEQ1 xref: UniProtKB:Q8TER4 xref: UniProtKB:Q96PH1 xref: UniProtKB:Q96PH2 xref: UniProtKB:Q96PJ8 xref: UniProtKB:Q96PJ9 xref: UniProtKB:Q9H6E0 xref: UniProtKB:Q9HAM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018823 ! NOX5_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0002719 ! hydrogen ion channel activity relationship: has_function CCO:F0003063 ! superoxide-generating NADPH oxidase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_function CCO:F0007987 ! NADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002137 ! regulation of fusion of sperm to egg plasma membrane [Term] id: CCO:B0058336 name: Q96PJ7_HUMAN def: "Ras-related GTP-binding protein RAB39" [UniProtKB:Q96PJ7] xref: EMBL:AAL05587.1 xref: UniProtKB:Q96PJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058337 name: RBM14_HUMAN def: "RNA-binding protein 14" [UniProtKB:Q96PK6] synonym: "RNA-binding motif protein 14" EXACT [UniProtKB:Q96PK6] synonym: "RRM-containing coactivator activator/modulator" EXACT [UniProtKB:Q96PK6] synonym: "Synaptotagmin-interacting protein" EXACT [UniProtKB:Q96PK6] synonym: "SYT-interacting protein" EXACT [UniProtKB:Q96PK6] xref: EMBL:AAC64058.1 xref: EMBL:AAH00488.1 xref: EMBL:AAK77961.1 xref: EMBL:AAK77962.1 xref: EMBL:BAD96550.1 xref: EMBL:CAH18161.1 xref: UniProtKB:O75932 xref: UniProtKB:Q53GV1 xref: UniProtKB:Q68DQ9 xref: UniProtKB:Q96PK5 xref: UniProtKB:Q96PK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013689 ! RBM14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001279 ! estrogen receptor signaling pathway relationship: participates_in CCO:P0002128 ! glucocorticoid receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0069777 ! RBM14_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0069778 ! RBM14_HUMAN-Phosphothreonine206 relationship: transforms_into CCO:B0069779 ! RBM14_HUMAN-Phosphoserine215 relationship: transforms_into CCO:B0069780 ! RBM14_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0069781 ! RBM14_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0069782 ! RBM14_HUMAN-Phosphoserine520 relationship: transforms_into CCO:B0069783 ! RBM14_HUMAN-Phosphoserine562 relationship: transforms_into CCO:B0069784 ! RBM14_HUMAN-Phosphothreonine572 relationship: transforms_into CCO:B0069785 ! RBM14_HUMAN-Phosphoserine582 relationship: transforms_into CCO:B0069786 ! RBM14_HUMAN-Phosphoserine618 relationship: transforms_into CCO:B0069787 ! RBM14_HUMAN-Phosphothreonine629 relationship: transforms_into CCO:B0069788 ! RBM14_HUMAN-Phosphoserine632 relationship: transforms_into CCO:B0069789 ! RBM14_HUMAN-Phosphoserine649 [Term] id: CCO:B0058338 name: Z385A_HUMAN def: "Zinc finger protein 385A" [UniProtKB:Q96PM9] synonym: "Hematopoietic zinc finger protein" EXACT [UniProtKB:Q96PM9] synonym: "Retinal zinc finger protein" EXACT [UniProtKB:Q96PM9] xref: EMBL:AAH29752.1 xref: EMBL:AAL08625.1 xref: EMBL:AAS19275.1 xref: EMBL:BAB14910.1 xref: EMBL:CAB55938.1 xref: EMBL:CAG33608.1 xref: UniProtKB:Q5VH53 xref: UniProtKB:Q96PM9 xref: UniProtKB:Q9H7R6 xref: UniProtKB:Q9UFU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020526 ! ZNF385A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058339 name: ADCYA_HUMAN def: "Adenylate cyclase type 10" [UniProtKB:Q96PN6] synonym: "Adenylate cyclase homolog" EXACT [UniProtKB:Q96PN6] synonym: "AH-related protein" EXACT [UniProtKB:Q96PN6] synonym: "EC 4.6.1.1" EXACT [UniProtKB:Q96PN6] synonym: "Germ cell soluble adenylyl cyclase" EXACT [UniProtKB:Q96PN6] synonym: "hsAC" EXACT [UniProtKB:Q96PN6] synonym: "sAC" EXACT [UniProtKB:Q96PN6] synonym: "Testicular soluble adenylyl cyclase" EXACT [UniProtKB:Q96PN6] xref: EMBL:AAF65931.1 xref: EMBL:AAF74296.1 xref: EMBL:AAI17367.1 xref: EMBL:AAI17373.1 xref: EMBL:AAK96045.1 xref: EMBL:AAL57036.1 xref: EMBL:CAA22684.1 xref: EMBL:CAI20073.1 xref: EMBL:CAI20074.1 xref: EMBL:CAI20146.1 xref: EMBL:CAI20147.1 xref: EMBL:EAW90804.1 xref: EMBL:EAW90807.1 xref: UniProtKB:O95558 xref: UniProtKB:Q5R329 xref: UniProtKB:Q5R330 xref: UniProtKB:Q8WXV4 xref: UniProtKB:Q96PN6 xref: UniProtKB:Q9NNX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016915 ! ADCY10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0065410 ! ADCYA_HUMAN-Phosphothreonine809 relationship: transforms_into CCO:B0065411 ! ADCYA_HUMAN-Phosphoserine810 [Term] id: CCO:B0058340 name: TREF1_HUMAN def: "Transcriptional-regulating factor 1" [UniProtKB:Q96PN7] synonym: "Breast cancer anti-estrogen resistance 2" EXACT [UniProtKB:Q96PN7] synonym: "Transcriptional-regulating protein 132" EXACT [UniProtKB:Q96PN7] synonym: "Zinc finger protein rapa" EXACT [UniProtKB:Q96PN7] synonym: "Zinc finger transcription factor TReP-132" EXACT [UniProtKB:Q96PN7] xref: EMBL:AAL01653.1 xref: EMBL:BAA92082.1 xref: EMBL:CAB88206.1 xref: EMBL:CAB88207.1 xref: EMBL:CAD92526.1 xref: EMBL:CAD92527.2 xref: EMBL:CAD92528.2 xref: UniProtKB:Q7Z6T2 xref: UniProtKB:Q7Z6T3 xref: UniProtKB:Q96PN7 xref: UniProtKB:Q9NQ72 xref: UniProtKB:Q9NQ73 xref: UniProtKB:Q9NUN9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020348 ! TRERF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002745 ! regulation of hormone biosynthetic process relationship: transforms_into CCO:B0071532 ! TREF1_HUMAN-Phosphoserine491 [Term] id: CCO:B0058341 name: IPP2L_HUMAN def: "Putative protein phosphatase inhibitor 2-like protein 1" [UniProtKB:Q96PQ5] synonym: "Protein phosphatase 1, regulatory subunit 2 pseudogene 1" EXACT [UniProtKB:Q96PQ5] xref: EMBL:AAL09300.1 xref: UniProtKB:Q96PQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018300 ! PPP1R2P1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0067122 ! IPP2L_HUMAN-Phosphothreonine73 relationship: transforms_into CCO:B0067123 ! IPP2L_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0067124 ! IPP2L_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0067125 ! IPP2L_HUMAN-Phosphoserine122 [Term] id: CCO:B0058342 name: ZN317_HUMAN def: "Zinc finger protein 317" [UniProtKB:Q96PQ6] xref: EMBL:AAL29182.1 xref: EMBL:AAL29188.1 xref: EMBL:AAL29190.1 xref: EMBL:AAL29191.1 xref: EMBL:BAB13414.1 xref: UniProtKB:Q96PM0 xref: UniProtKB:Q96PM1 xref: UniProtKB:Q96PQ6 xref: UniProtKB:Q96PT2 xref: UniProtKB:Q9HCI4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020700 ! ZNF317_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058343 name: DUX5_HUMAN def: "Double homeobox protein 5" [UniProtKB:Q96PT3] xref: EMBL:AAD33598.1 xref: EMBL:AAL02243.1 xref: UniProtKB:Q96PT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017642 ! DUX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058344 name: DUX3_HUMAN def: "Putative double homeobox protein 3" [UniProtKB:Q96PT4] xref: EMBL:AAD33597.1 xref: EMBL:AAL02242.1 xref: UniProtKB:Q96PT4 xref: UniProtKB:Q9UND2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017640 ! DUX3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058345 name: QKI_HUMAN def: "Protein quaking" [UniProtKB:Q96PU8] synonym: "Hqk" EXACT [UniProtKB:Q96PU8] synonym: "HqkI" EXACT [UniProtKB:Q96PU8] xref: EMBL:AAF63412.1 xref: EMBL:AAF63413.1 xref: EMBL:AAF63414.1 xref: EMBL:AAF63415.1 xref: EMBL:AAF63416.1 xref: EMBL:AAF63417.1 xref: EMBL:AAH12222.1 xref: EMBL:AAH19917.1 xref: EMBL:AAV98358.1 xref: EMBL:ABC88600.1 xref: EMBL:BAB55032.1 xref: EMBL:BAB69496.1 xref: EMBL:BAB69497.1 xref: EMBL:BAB69498.1 xref: EMBL:BAB69499.1 xref: EMBL:BAB69681.1 xref: EMBL:CAI21651.1 xref: EMBL:CAI21652.1 xref: EMBL:CAI21653.1 xref: EMBL:CAI23022.1 xref: EMBL:CAI23023.1 xref: EMBL:CAI23024.1 xref: UniProtKB:Q2I375 xref: UniProtKB:Q5MJQ1 xref: UniProtKB:Q969L9 xref: UniProtKB:Q96EJ3 xref: UniProtKB:Q96KA3 xref: UniProtKB:Q96PU6 xref: UniProtKB:Q96PU7 xref: UniProtKB:Q96PU8 xref: UniProtKB:Q9P0X6 xref: UniProtKB:Q9P0X7 xref: UniProtKB:Q9P0X8 xref: UniProtKB:Q9P0X9 xref: UniProtKB:Q9P0Y0 xref: UniProtKB:Q9P0Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019566 ! QKI_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015724 ! hnrpk-hqk physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0058346 name: Q96PV9_HUMAN xref: UniProtKB:Q96PV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058347 name: PKH4B_HUMAN def: "Pleckstrin homology domain-containing family G member 4B" [UniProtKB:Q96PX9] xref: EMBL:BAB67802.2 xref: UniProtKB:Q96PX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019410 ! PLEKHG4B_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0058348 name: FMNL2_HUMAN def: "Formin-like protein 2" [UniProtKB:Q96PY5] synonym: "Formin homology 2 domain-containing protein 2" EXACT [UniProtKB:Q96PY5] xref: EMBL:AAI13879.1 xref: EMBL:AAI14439.1 xref: EMBL:BAB67795.1 xref: EMBL:CAD39058.1 xref: UniProtKB:Q14CC9 xref: UniProtKB:Q8N3E0 xref: UniProtKB:Q96PY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017814 ! FMNL2_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0003531 ! Rho GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066216 ! FMNL2_HUMAN-Phosphoserine171 relationship: transforms_into CCO:B0066217 ! FMNL2_HUMAN-Phosphoserine1017 [Term] id: CCO:B0058349 name: ASB2_HUMAN def: "Ankyrin repeat and SOCS box protein 2" [UniProtKB:Q96Q27] synonym: "ASB-2" EXACT [UniProtKB:Q96Q27] xref: EMBL:AAD45345.1 xref: EMBL:AAH32354.1 xref: EMBL:BAB64532.1 xref: EMBL:CAB70899.1 xref: EMBL:CAC17765.1 xref: UniProtKB:Q96Q27 xref: UniProtKB:Q9NSU5 xref: UniProtKB:Q9Y567 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017066 ! ASB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058350 name: ALS2_HUMAN def: "Alsin" [UniProtKB:Q96Q42] synonym: "Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein" EXACT [UniProtKB:Q96Q42] synonym: "Amyotrophic lateral sclerosis protein 2" EXACT [UniProtKB:Q96Q42] xref: EMBL:AAH29174.1 xref: EMBL:AAL14103.1 xref: EMBL:BAB13389.2 xref: EMBL:BAB14362.1 xref: EMBL:BAB69014.1 xref: EMBL:BAB69015.1 xref: UniProtKB:Q8N1E0 xref: UniProtKB:Q96PC4 xref: UniProtKB:Q96Q41 xref: UniProtKB:Q96Q42 xref: UniProtKB:Q9H973 xref: UniProtKB:Q9HCK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016953 ! ALS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000486 ! receptor recycling relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: participates_in CCO:P0001682 ! positive regulation of Rac GTPase activity relationship: participates_in CCO:P0001984 ! positive regulation of Rac protein signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0065608 ! ALS2_HUMAN-Phosphoserine483 relationship: transforms_into CCO:B0065609 ! ALS2_HUMAN-Phosphoserine492 relationship: transforms_into CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: transforms_into CCO:B0065611 ! ALS2_HUMAN-Phosphoserine1464 [Term] id: CCO:B0058351 name: DERL3_HUMAN def: "Derlin-3" [UniProtKB:Q96Q80] synonym: "Degradation in endoplasmic reticulum protein 3" EXACT [UniProtKB:Q96Q80] synonym: "Der1-like protein 3" EXACT [UniProtKB:Q96Q80] synonym: "DERtrin-3" EXACT [UniProtKB:Q96Q80] xref: EMBL:AAH57830.1 xref: EMBL:BAB68409.1 xref: EMBL:BAC86311.1 xref: EMBL:CAG30258.1 xref: UniProtKB:Q6ICJ6 xref: UniProtKB:Q6PEX0 xref: UniProtKB:Q6ZUB5 xref: UniProtKB:Q96Q80 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017560 ! DERL3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response [Term] id: CCO:B0058352 name: DEPD7_HUMAN def: "DEP domain-containing protein 7" [UniProtKB:Q96QD5] synonym: "Protein TR2/D15" EXACT [UniProtKB:Q96QD5] xref: EMBL:AAH30970.1 xref: EMBL:AAM22871.1 xref: EMBL:CAB53247.1 xref: EMBL:CAC48255.1 xref: UniProtKB:Q8N602 xref: UniProtKB:Q8NCU9 xref: UniProtKB:Q96QD5 xref: UniProtKB:Q9UGK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017557 ! DEPDC7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0064740 ! DEPD7_HUMAN-Phosphoserine152 [Term] id: CCO:B0058353 name: PRAM_HUMAN def: "PML-RARA-regulated adapter molecule 1" [UniProtKB:Q96QH2] synonym: "PRAM" EXACT [UniProtKB:Q96QH2] synonym: "PRAM-1" EXACT [UniProtKB:Q96QH2] xref: EMBL:AAH28012.1 xref: EMBL:CAC17767.1 xref: UniProtKB:Q8N6W7 xref: UniProtKB:Q96QH2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019486 ! PRAM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0002186 ! regulation of neutrophil degranulation relationship: transforms_into CCO:B0069486 ! PRAM_HUMAN-Phosphoserine382 [Term] id: CCO:B0058354 name: Q96QH7_HUMAN def: "Zinc finger protein 182" [UniProtKB:Q96QH7] synonym: "Zinc finger protein 21 (KOX 14), isoform CRA_b" EXACT [UniProtKB:Q96QH7] xref: EMBL:AAI14217.1 xref: EMBL:CAC41951.1 xref: EMBL:EAW59335.1 xref: UniProtKB:Q96QH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020643 ! ZNF182_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058355 name: Q96QI0_HUMAN def: "Synovial sarcoma, X breakpoint 6" [UniProtKB:Q96QI0] xref: EMBL:CAC41947.1 xref: UniProtKB:Q96QI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020054 ! SSX6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058356 name: SG3A1_HUMAN def: "Secretoglobin family 3A member 1 precursor" [UniProtKB:Q96QR1] synonym: "Cytokine HIN-1" EXACT [UniProtKB:Q96QR1] synonym: "High in normal 1" EXACT [UniProtKB:Q96QR1] synonym: "Pneumo secretory protein 2" EXACT [UniProtKB:Q96QR1] synonym: "PnSP-2" EXACT [UniProtKB:Q96QR1] synonym: "Uteroglobin-related protein 2" EXACT [UniProtKB:Q96QR1] xref: EMBL:AAH29176.1 xref: EMBL:AAH72673.1 xref: EMBL:AAK82942.1 xref: EMBL:AAL26217.1 xref: EMBL:AAQ04481.1 xref: EMBL:AAQ89423.1 xref: UniProtKB:Q96PL0 xref: UniProtKB:Q96QR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019880 ! SCGB3A1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0058357 name: ARX_HUMAN def: "Homeobox protein ARX" [UniProtKB:Q96QS3] synonym: "Aristaless-related homeobox" EXACT [UniProtKB:Q96QS3] xref: EMBL:AAK93901.1 xref: UniProtKB:Q96QS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017054 ! ARX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058358 name: MAGI1_HUMAN def: "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1" [UniProtKB:Q96QZ7] synonym: "AIP3" EXACT [UniProtKB:Q96QZ7] synonym: "Atrophin-1-interacting protein 3" EXACT [UniProtKB:Q96QZ7] synonym: "BAI1-associated protein 1" EXACT [UniProtKB:Q96QZ7] synonym: "BAP-1" EXACT [UniProtKB:Q96QZ7] synonym: "MAGI-1" EXACT [UniProtKB:Q96QZ7] synonym: "Membrane-associated guanylate kinase inverted 1" EXACT [UniProtKB:Q96QZ7] synonym: "Trinucleotide repeat-containing gene 19 protein" EXACT [UniProtKB:Q96QZ7] synonym: "WW domain-containing protein 3" EXACT [UniProtKB:Q96QZ7] synonym: "WWP3" EXACT [UniProtKB:Q96QZ7] xref: EMBL:AAC04844.1 xref: EMBL:AAC51326.1 xref: EMBL:AAK94064.1 xref: EMBL:AAK94065.1 xref: EMBL:AAK94066.1 xref: EMBL:BAA32002.1 xref: UniProtKB:O00309 xref: UniProtKB:O43863 xref: UniProtKB:O75085 xref: UniProtKB:Q96QZ7 xref: UniProtKB:Q96QZ8 xref: UniProtKB:Q96QZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018559 ! MAGI1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0016326 ! magi1-adrb1-1 direct interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0067853 ! MAGI1_HUMAN-Phosphotyrosine866 [Term] id: CCO:B0058359 name: OR2M4_HUMAN def: "Olfactory receptor 2M4" [UniProtKB:Q96R27] synonym: "HTPCRX18" EXACT [UniProtKB:Q96R27] synonym: "Olfactory receptor OR1-55" EXACT [UniProtKB:Q96R27] synonym: "Olfactory receptor TPCR100" EXACT [UniProtKB:Q96R27] synonym: "OST710" EXACT [UniProtKB:Q96R27] xref: EMBL:AAK95102.1 xref: EMBL:BAC06166.1 xref: EMBL:CAA61813.1 xref: EMBL:CAH71663.1 xref: EMBL:DAA04881.1 xref: UniProtKB:Q15611 xref: UniProtKB:Q8NG82 xref: UniProtKB:Q96R27 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019111 ! OR2M4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058360 name: OR2M2_HUMAN def: "Olfactory receptor 2M2" [UniProtKB:Q96R28] synonym: "OST423" EXACT [UniProtKB:Q96R28] xref: EMBL:AAK95101.1 xref: EMBL:CAM45730.1 xref: UniProtKB:A3KFT4 xref: UniProtKB:Q96R28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019109 ! OR2M2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058361 name: OR2V2_HUMAN def: "Olfactory receptor 2V2" [UniProtKB:Q96R30] synonym: "Olfactory receptor OR5-3" EXACT [UniProtKB:Q96R30] xref: EMBL:AAK95099.1 xref: EMBL:BAC05900.1 xref: EMBL:DAA04644.1 xref: UniProtKB:Q6IFL6 xref: UniProtKB:Q8NGV1 xref: UniProtKB:Q96R30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019123 ! OR2V2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058362 name: OR2A7_HUMAN def: "Olfactory receptor 2A7" [UniProtKB:Q96R45] synonym: "Olfactory receptor OR7-18" EXACT [UniProtKB:Q96R45] xref: EMBL:AAK95083.1 xref: EMBL:DAA04616.1 xref: UniProtKB:Q6IFP4 xref: UniProtKB:Q96R45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019083 ! OR2A7_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058363 name: O2A14_HUMAN def: "Olfactory receptor 2A14" [UniProtKB:Q96R47] synonym: "Olfactory receptor OR7-12" EXACT [UniProtKB:Q96R47] synonym: "OST182" EXACT [UniProtKB:Q96R47] xref: EMBL:AAK95081.1 xref: EMBL:BAC05916.1 xref: EMBL:DAA04819.1 xref: UniProtKB:Q6IF41 xref: UniProtKB:Q8NGT8 xref: UniProtKB:Q96R47 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018955 ! OR2A14_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058364 name: OR2A5_HUMAN def: "Olfactory receptor 2A5" [UniProtKB:Q96R48] synonym: "Olfactory receptor 7-138/7-141" EXACT [UniProtKB:Q96R48] synonym: "OR7-138" EXACT [UniProtKB:Q96R48] synonym: "OR7-141" EXACT [UniProtKB:Q96R48] xref: EMBL:AAC39630.1 xref: EMBL:AAC39633.1 xref: EMBL:AAK95080.1 xref: UniProtKB:O43885 xref: UniProtKB:O43888 xref: UniProtKB:Q96R48 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019082 ! OR2A5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058365 name: O14A2_HUMAN def: "Olfactory receptor 14A2" [UniProtKB:Q96R54] synonym: "Olfactory receptor 5AX1" EXACT [UniProtKB:Q96R54] synonym: "Olfactory receptor OR1-31" EXACT [UniProtKB:Q96R54] xref: EMBL:AAK95074.1 xref: UniProtKB:Q96R54 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022469 ! OR14A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058366 name: OR4CC_HUMAN def: "Olfactory receptor 4C12" [UniProtKB:Q96R67] synonym: "Olfactory receptor OR11-259" EXACT [UniProtKB:Q96R67] xref: EMBL:AAK95061.1 xref: EMBL:DAA04811.1 xref: UniProtKB:Q6IF49 xref: UniProtKB:Q96R67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019139 ! OR4C12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058367 name: OR4F4_HUMAN def: "Olfactory receptor 4F4" [UniProtKB:Q96R69] synonym: "HS14a-1-A" EXACT [UniProtKB:Q96R69] synonym: "Olfactory receptor OR19-3" EXACT [UniProtKB:Q96R69] xref: EMBL:AAK95059.1 xref: EMBL:DAA04621.1 xref: UniProtKB:Q6IFN9 xref: UniProtKB:Q96R69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019155 ! OR4F4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058368 name: OR4K3_HUMAN def: "Olfactory receptor 4K3" [UniProtKB:Q96R72] synonym: "Olfactory receptor OR14-14" EXACT [UniProtKB:Q96R72] xref: EMBL:AAK95056.1 xref: EMBL:DAA04756.1 xref: UniProtKB:Q6IFA4 xref: UniProtKB:Q96R72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019160 ! OR4K3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058369 name: OR1F2_HUMAN def: "Olfactory receptor 1F2" [UniProtKB:Q96R84] synonym: "OLFmf2" EXACT [UniProtKB:Q96R84] xref: EMBL:AAK95043.1 xref: UniProtKB:Q96R84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019065 ! OR1F2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058370 name: OR7D2_HUMAN def: "Olfactory receptor 7D2" [UniProtKB:Q96RA2] synonym: "HTPCRH03" EXACT [UniProtKB:Q96RA2] synonym: "Olfactory receptor 19-4" EXACT [UniProtKB:Q96RA2] synonym: "OR19-4" EXACT [UniProtKB:Q96RA2] xref: EMBL:AAK95022.1 xref: EMBL:BAC04554.1 xref: EMBL:BAC06143.1 xref: UniProtKB:Q8N133 xref: UniProtKB:Q96RA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019219 ! OR7D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058371 name: OR8B2_HUMAN def: "Olfactory receptor 8B2" [UniProtKB:Q96RD0] xref: EMBL:AAK94993.1 xref: UniProtKB:Q96RD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019223 ! OR8B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058372 name: OR6C1_HUMAN def: "Olfactory receptor 6C1" [UniProtKB:Q96RD1] synonym: "OST267" EXACT [UniProtKB:Q96RD1] xref: EMBL:AAK94991.1 xref: UniProtKB:Q96RD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019198 ! OR6C1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058373 name: O52E6_HUMAN def: "Olfactory receptor 52E6" [UniProtKB:Q96RD3] xref: EMBL:AAK94989.1 xref: EMBL:BAC06034.1 xref: UniProtKB:Q96RD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019011 ! OR52E6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058374 name: BTB14_HUMAN def: "BTB/POZ domain-containing protein 14B" [UniProtKB:Q96RE7] synonym: "NAC-1" EXACT [UniProtKB:Q96RE7] synonym: "Nucleus accumbens-1" EXACT [UniProtKB:Q96RE7] xref: EMBL:AAH55396.1 xref: EMBL:AAK83885.1 xref: UniProtKB:Q96RE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017186 ! BTBD14B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064010 ! BTB14_HUMAN-Phosphoserine259 [Term] id: CCO:B0058375 name: PASK_HUMAN def: "PAS domain-containing serine/threonine-protein kinase" [UniProtKB:Q96RG2] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q96RG2] synonym: "hPASK" EXACT [UniProtKB:Q96RG2] synonym: "PAS-kinase" EXACT [UniProtKB:Q96RG2] synonym: "PASKIN" EXACT [UniProtKB:Q96RG2] xref: EMBL:AAB50198.1 xref: EMBL:AAH43495.1 xref: EMBL:AAH63585.1 xref: EMBL:AAK69752.1 xref: EMBL:BAA09484.2 xref: EMBL:CAH18087.1 xref: UniProtKB:Q68DY3 xref: UniProtKB:Q6GSJ5 xref: UniProtKB:Q86XH6 xref: UniProtKB:Q96RG2 xref: UniProtKB:Q99763 xref: UniProtKB:Q9UFR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019302 ! PASK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069118 ! PASK_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0069119 ! PASK_HUMAN-Phosphoserine524 relationship: transforms_into CCO:B0069120 ! PASK_HUMAN-Phosphoserine533 relationship: transforms_into CCO:B0069121 ! PASK_HUMAN-Phosphothreonine1161 relationship: transforms_into CCO:B0069122 ! PASK_HUMAN-Phosphothreonine1165 relationship: transforms_into CCO:B0069123 ! PASK_HUMAN-Phosphoserine1273 relationship: transforms_into CCO:B0069124 ! PASK_HUMAN-Phosphoserine1277 relationship: transforms_into CCO:B0069125 ! PASK_HUMAN-Phosphoserine1280 [Term] id: CCO:B0058376 name: NR1H4_HUMAN def: "Bile acid receptor" [UniProtKB:Q96RI1] synonym: "Farnesoid X-activated receptor" EXACT [UniProtKB:Q96RI1] synonym: "Farnesol receptor HRR-1" EXACT [UniProtKB:Q96RI1] synonym: "Nuclear receptor subfamily 1 group H member 4" EXACT [UniProtKB:Q96RI1] synonym: "Retinoid X receptor-interacting protein 14" EXACT [UniProtKB:Q96RI1] synonym: "RXR-interacting protein 14" EXACT [UniProtKB:Q96RI1] xref: EMBL:AAB08107.1 xref: EMBL:AAK60271.1 xref: EMBL:AAM53550.1 xref: EMBL:AAM53551.1 xref: UniProtKB:Q8NFP5 xref: UniProtKB:Q8NFP6 xref: UniProtKB:Q92943 xref: UniProtKB:Q96RI1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018853 ! NR1H4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058377 name: TAAR6_HUMAN def: "Trace amine-associated receptor 6" [UniProtKB:Q96RI8] synonym: "TaR-4" EXACT [UniProtKB:Q96RI8] synonym: "Trace amine receptor 4" EXACT [UniProtKB:Q96RI8] xref: EMBL:AAH69157.1 xref: EMBL:AAK71243.1 xref: EMBL:AAO24661.1 xref: EMBL:CAH72099.1 xref: UniProtKB:Q5VUQ4 xref: UniProtKB:Q96RI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020124 ! TAAR6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058378 name: TAAR9_HUMAN def: "Trace amine-associated receptor 9" [UniProtKB:Q96RI9] synonym: "TaR-3" EXACT [UniProtKB:Q96RI9] synonym: "Trace amine receptor 3" EXACT [UniProtKB:Q96RI9] xref: EMBL:AAK71240.1 xref: EMBL:AAO24660.1 xref: UniProtKB:Q96RI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020126 ! TAAR9_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058379 name: TAAR1_HUMAN def: "Trace amine-associated receptor 1" [UniProtKB:Q96RJ0] synonym: "TaR-1" EXACT [UniProtKB:Q96RJ0] synonym: "Trace amine receptor 1" EXACT [UniProtKB:Q96RJ0] xref: EMBL:AAG17112.1 xref: EMBL:AAI01826.1 xref: EMBL:AAI12195.1 xref: EMBL:AAK71236.1 xref: EMBL:AAO22154.1 xref: EMBL:CAH72104.1 xref: UniProtKB:Q2M1W5 xref: UniProtKB:Q3MIH8 xref: UniProtKB:Q5VUQ1 xref: UniProtKB:Q96RJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020120 ! TAAR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000150 ! trace-amine receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058380 name: FER3L_HUMAN def: "Fer3-like protein" [UniProtKB:Q96RJ6] synonym: "Basic helix-loop-helix protein N-twist" EXACT [UniProtKB:Q96RJ6] synonym: "Nephew of atonal 3" EXACT [UniProtKB:Q96RJ6] synonym: "Neuronal twist" EXACT [UniProtKB:Q96RJ6] xref: EMBL:AAH69147.1 xref: EMBL:AAI01136.1 xref: EMBL:AAI01137.1 xref: EMBL:AAI01138.1 xref: EMBL:AAI01139.1 xref: EMBL:AAK72956.1 xref: EMBL:AAN04086.1 xref: EMBL:EAL24278.1 xref: EMBL:EAW93712.1 xref: UniProtKB:Q495K0 xref: UniProtKB:Q96RJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017774 ! FERD3L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058381 name: UIMC1_HUMAN def: "Ubiquitin interaction motif-containing protein 1" [UniProtKB:Q96RL1] synonym: "Nuclear zinc finger protein RAP80" EXACT [UniProtKB:Q96RL1] synonym: "Receptor-associated protein 80" EXACT [UniProtKB:Q96RL1] synonym: "Retinoid X receptor-interacting protein 110" EXACT [UniProtKB:Q96RL1] xref: EMBL:AAF14875.1 xref: EMBL:AAG59851.1 xref: EMBL:AAG59855.1 xref: EMBL:AAH06078.1 xref: EMBL:AAH32561.1 xref: EMBL:AAK61871.1 xref: EMBL:CAD97618.1 xref: UniProtKB:Q5XKQ1 xref: UniProtKB:Q7Z3W7 xref: UniProtKB:Q8N5B9 xref: UniProtKB:Q96RL1 xref: UniProtKB:Q9BZR1 xref: UniProtKB:Q9BZR5 xref: UniProtKB:Q9UHX7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020405 ! UIMC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020573 ! znhit4-rxrip110 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0071719 ! UIMC1_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0071720 ! UIMC1_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0071721 ! UIMC1_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0071722 ! UIMC1_HUMAN-Phosphoserine402 relationship: transforms_into CCO:B0071723 ! UIMC1_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0071724 ! UIMC1_HUMAN-Phosphoserine419 relationship: transforms_into CCO:B0071725 ! UIMC1_HUMAN-Phosphoserine597 relationship: transforms_into CCO:B0071726 ! UIMC1_HUMAN-Phosphoserine627 relationship: transforms_into CCO:B0071727 ! UIMC1_HUMAN-Phosphoserine653 relationship: transforms_into CCO:B0071728 ! UIMC1_HUMAN-Phosphoserine677 [Term] id: CCO:B0058382 name: PEO1_HUMAN def: "Twinkle protein, mitochondrial precursor" [UniProtKB:Q96RR1] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q96RR1] synonym: "Progressive external ophthalmoplegia 1 protein" EXACT [UniProtKB:Q96RR1] synonym: "T7 gp4-like protein with intramitochondrial nucleoid localization" EXACT [UniProtKB:Q96RR1] synonym: "T7-like mitochondrial DNA helicase" EXACT [UniProtKB:Q96RR1] xref: EMBL:AAH13349.1 xref: EMBL:AAK69558.1 xref: EMBL:AAK69559.1 xref: EMBL:CAE45905.1 xref: EMBL:CAI10924.1 xref: EMBL:CAI10925.1 xref: UniProtKB:Q6MZX2 xref: UniProtKB:Q6PJP5 xref: UniProtKB:Q96RR0 xref: UniProtKB:Q96RR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019365 ! PEO1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058383 name: KKCC2_HUMAN def: "Calcium/calmodulin-dependent protein kinase kinase 2" [UniProtKB:Q96RR4] synonym: "Calcium/calmodulin-dependent protein kinase kinase beta" EXACT [UniProtKB:Q96RR4] synonym: "CaM-kinase kinase beta" EXACT [UniProtKB:Q96RR4] synonym: "CaM-KK beta" EXACT [UniProtKB:Q96RR4] synonym: "CaMKK beta" EXACT [UniProtKB:Q96RR4] synonym: "EC 2.7.11.17" EXACT [UniProtKB:Q96RR4] xref: EMBL:AAC72943.1 xref: EMBL:AAD04566.1 xref: EMBL:AAD31507.1 xref: EMBL:AAH00318.2 xref: EMBL:AAH26060.1 xref: EMBL:AAK64600.1 xref: EMBL:AAK64601.1 xref: EMBL:AAK91829.1 xref: EMBL:AAK91830.1 xref: EMBL:AAL37215.1 xref: EMBL:AAL37216.1 xref: EMBL:AAL37217.1 xref: EMBL:AAL37218.1 xref: EMBL:BAA34507.2 xref: EMBL:BAC19840.1 xref: EMBL:BAC19841.1 xref: EMBL:CAD38990.1 xref: UniProtKB:O94883 xref: UniProtKB:Q8IUG2 xref: UniProtKB:Q8IUG3 xref: UniProtKB:Q8N3I4 xref: UniProtKB:Q8WY03 xref: UniProtKB:Q8WY04 xref: UniProtKB:Q8WY05 xref: UniProtKB:Q8WY06 xref: UniProtKB:Q96RP1 xref: UniProtKB:Q96RP2 xref: UniProtKB:Q96RR3 xref: UniProtKB:Q96RR4 xref: UniProtKB:Q9BWE9 xref: UniProtKB:Q9UER3 xref: UniProtKB:Q9UES2 xref: UniProtKB:Q9Y5N2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018407 ! CAMKK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017425 ! cep63-camkk2 physical interaction relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0067369 ! KKCC2_HUMAN-Phosphoserine129 relationship: transforms_into CCO:B0067370 ! KKCC2_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0067371 ! KKCC2_HUMAN-Phosphoserine495 [Term] id: CCO:B0058384 name: RB40C_HUMAN def: "Ras-related protein Rab-40C" [UniProtKB:Q96S21] synonym: "Rar-like protein" EXACT [UniProtKB:Q96S21] synonym: "Ras-like protein family member 8C" EXACT [UniProtKB:Q96S21] synonym: "SOCS box-containing protein RAR3" EXACT [UniProtKB:Q96S21] xref: EMBL:AAK61236.1 xref: EMBL:CAB06484.2 xref: UniProtKB:O60795 xref: UniProtKB:Q4TT41 xref: UniProtKB:Q96S21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019642 ! RAB40C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058385 name: KS6C1_HUMAN def: "Ribosomal protein S6 kinase delta-1" [UniProtKB:Q96S38] synonym: "52 kDa ribosomal protein S6 kinase" EXACT [UniProtKB:Q96S38] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q96S38] synonym: "Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein" EXACT [UniProtKB:Q96S38] synonym: "SPHK1-binding protein" EXACT [UniProtKB:Q96S38] xref: EMBL:AAF13027.1 xref: EMBL:AAI04770.1 xref: EMBL:AAL84818.1 xref: EMBL:BAB63956.1 xref: EMBL:CAB92850.1 xref: EMBL:CAH70703.1 xref: EMBL:CAH71999.1 xref: EMBL:CAH73804.1 xref: UniProtKB:Q8TDD3 xref: UniProtKB:Q96S38 xref: UniProtKB:Q9NSF4 xref: UniProtKB:Q9UL66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018446 ! RPS6KC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067490 ! KS6C1_HUMAN-Phosphoserine423 relationship: transforms_into CCO:B0067491 ! KS6C1_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0067492 ! KS6C1_HUMAN-Phosphoserine583 relationship: transforms_into CCO:B0067493 ! KS6C1_HUMAN-Phosphoserine640 [Term] id: CCO:B0058386 name: WRIP1_HUMAN def: "ATPase WRNIP1" [UniProtKB:Q96S55] synonym: "Werner helicase-interacting protein 1" EXACT [UniProtKB:Q96S55] xref: EMBL:AAF80563.1 xref: EMBL:AAH18923.1 xref: EMBL:BAB15383.1 xref: EMBL:BAB60709.1 xref: EMBL:BAD92960.1 xref: EMBL:BAD97313.1 xref: EMBL:CAH73663.1 xref: EMBL:CAH73664.1 xref: EMBL:CAH73665.1 xref: EMBL:CAH73666.1 xref: UniProtKB:Q53EP6 xref: UniProtKB:Q59ET8 xref: UniProtKB:Q5W0E2 xref: UniProtKB:Q5W0E4 xref: UniProtKB:Q8WV26 xref: UniProtKB:Q96S55 xref: UniProtKB:Q9H681 xref: UniProtKB:Q9NRJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020499 ! WRNIP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000442 ! DNA synthesis during DNA repair relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0001247 ! regulation of DNA replication initiation relationship: transforms_into CCO:B0071868 ! WRIP1_HUMAN-Phosphoserine65 relationship: transforms_into CCO:B0071869 ! WRIP1_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0071870 ! WRIP1_HUMAN-Phosphothreonine85 relationship: transforms_into CCO:B0071871 ! WRIP1_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0071872 ! WRIP1_HUMAN-Phosphoserine92 relationship: transforms_into CCO:B0071873 ! WRIP1_HUMAN-Phosphothreonine116 relationship: transforms_into CCO:B0071874 ! WRIP1_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0071875 ! WRIP1_HUMAN-Phosphotyrosine534 relationship: transforms_into CCO:B0071876 ! WRIP1_HUMAN-Phosphotyrosine562 [Term] id: CCO:B0058387 name: AXUD1_HUMAN def: "Axin-1 up-regulated gene 1 protein" [UniProtKB:Q96S65] synonym: "CSRNP-1" EXACT [UniProtKB:Q96S65] synonym: "Cysteine/serine-rich nuclear protein 1" EXACT [UniProtKB:Q96S65] synonym: "Protein URAX1" EXACT [UniProtKB:Q96S65] synonym: "TAIP-3" EXACT [UniProtKB:Q96S65] synonym: "TGF-beta-induced apoptosis protein 3" EXACT [UniProtKB:Q96S65] xref: EMBL:AAH38949.1 xref: EMBL:BAB61065.1 xref: EMBL:BAB79450.1 xref: EMBL:CAH10719.1 xref: UniProtKB:Q69YY5 xref: UniProtKB:Q96S65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017107 ! AXUD1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058388 name: RSLAB_HUMAN def: "Ras-like protein family member 10B precursor" [UniProtKB:Q96S79] synonym: "Ras-like protein VTS58635" EXACT [UniProtKB:Q96S79] xref: EMBL:AAH41133.1 xref: EMBL:BAB60894.1 xref: UniProtKB:Q96S79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019800 ! RASL10B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0070249 ! RSLAB_HUMAN-Cysteine methyl ester200 [Term] id: CCO:B0058389 name: PKHF1_HUMAN def: "Pleckstrin homology domain-containing family F member 1" [UniProtKB:Q96S99] synonym: "Apoptosis-inducing protein" EXACT [UniProtKB:Q96S99] synonym: "Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains" EXACT [UniProtKB:Q96S99] synonym: "PH and FYVE domain-containing protein 1" EXACT [UniProtKB:Q96S99] synonym: "PH domain-containing family F member 1" EXACT [UniProtKB:Q96S99] synonym: "Phafin-1" EXACT [UniProtKB:Q96S99] synonym: "Zinc finger FYVE domain-containing protein 15" EXACT [UniProtKB:Q96S99] xref: EMBL:AAH02744.1 xref: EMBL:AAK67626.2 xref: EMBL:AAL30773.1 xref: EMBL:BAB55349.1 xref: UniProtKB:Q96K11 xref: UniProtKB:Q96S99 xref: UniProtKB:Q9BUB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019412 ! PLEKHF1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:P0000672 ! induction of apoptosis [Term] id: CCO:B0058390 name: DMTA2_HUMAN def: "Doublesex- and mab-3-related transcription factor A2" [UniProtKB:Q96SC8] synonym: "Doublesex- and mab-3-related transcription factor 5" EXACT [UniProtKB:Q96SC8] xref: EMBL:CAC37946.1 xref: EMBL:CAI23011.1 xref: UniProtKB:Q5TFQ3 xref: UniProtKB:Q96SC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017594 ! DMRTA2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058391 name: Q96SE4_HUMAN def: "DNA polymerase theta" [UniProtKB:Q96SE4] xref: EMBL:AAK39635.1 xref: UniProtKB:Q96SE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021197 ! POLQ_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058392 name: FIZ1_HUMAN def: "Flt3-interacting zinc finger protein 1" [UniProtKB:Q96SL8] synonym: "Zinc finger protein 798" EXACT [UniProtKB:Q96SL8] xref: EMBL:BAB55286.1 xref: EMBL:BAD18728.1 xref: UniProtKB:Q6ZMJ7 xref: UniProtKB:Q96SL8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017809 ! FIZ1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066197 ! FIZ1_HUMAN-Phosphothreonine74 [Term] id: CCO:B0058393 name: ZN587_HUMAN def: "Zinc finger protein 587" [UniProtKB:Q96SQ5] xref: EMBL:AAI26238.1 xref: EMBL:AAI26240.1 xref: EMBL:BAB55235.1 xref: EMBL:BAD18717.1 xref: UniProtKB:A0AV72 xref: UniProtKB:Q6ZMK8 xref: UniProtKB:Q96SQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020840 ! ZNF587_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058394 name: ATOH8_HUMAN def: "Protein atonal homolog 8" [UniProtKB:Q96SQ7] synonym: "Helix-loop-helix protein hATH-6" EXACT [UniProtKB:Q96SQ7] xref: EMBL:AAH21207.1 xref: EMBL:AAH94832.1 xref: EMBL:AAO85773.1 xref: EMBL:BAB55233.1 xref: EMBL:BAC11135.1 xref: EMBL:CAH56263.1 xref: UniProtKB:Q504S2 xref: UniProtKB:Q659B0 xref: UniProtKB:Q96SQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017101 ! ATOH8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058395 name: ZN382_HUMAN def: "Zinc finger protein 382" [UniProtKB:Q96SR6] synonym: "KRAB/Zinc finger suppressor protein 1" EXACT [UniProtKB:Q96SR6] synonym: "KS1" EXACT [UniProtKB:Q96SR6] xref: EMBL:AAM48246.1 xref: EMBL:BAB55217.1 xref: UniProtKB:Q96SR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020723 ! ZNF382_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058396 name: Q96SZ0_HUMAN xref: UniProtKB:Q96SZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000600 ! cytochrome-c oxidase activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0003077 ! cell division [Term] id: CCO:B0058397 name: ZSC10_HUMAN def: "Zinc finger and SCAN domain-containing protein 10" [UniProtKB:Q96SZ4] synonym: "Zinc finger protein 206" EXACT [UniProtKB:Q96SZ4] xref: EMBL:BAB55124.1 xref: UniProtKB:Q96SZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020999 ! ZSCAN10_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058398 name: RSF1_HUMAN def: "Remodeling and spacing factor 1" [UniProtKB:Q96T23] synonym: "HBV pX-associated protein 8" EXACT [UniProtKB:Q96T23] synonym: "Hepatitis B virus X-associated protein" EXACT [UniProtKB:Q96T23] synonym: "p325 subunit of RSF chromatin-remodeling complex" EXACT [UniProtKB:Q96T23] synonym: "Rsf-1" EXACT [UniProtKB:Q96T23] xref: EMBL:AAF61709.2 xref: EMBL:AAG43114.1 xref: EMBL:AAH46124.2 xref: EMBL:AAK57515.1 xref: EMBL:BAA91591.1 xref: UniProtKB:Q86X86 xref: UniProtKB:Q96T23 xref: UniProtKB:Q9H3L8 xref: UniProtKB:Q9NVZ8 xref: UniProtKB:Q9NYU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019798 ! RSF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015970 ! hbxap-smarca5-3 direct interaction relationship: participates_in CCO:I0017399 ! hbxap-smarca5-4 physical interaction relationship: participates_in CCO:I0017912 ! hbxap-smarca5 physical interaction relationship: participates_in CCO:I0017913 ! hbxap-smarca5-1 physical interaction relationship: participates_in CCO:I0018218 ! hbxap-smarca5-2 colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002910 ! positive regulation of viral transcription relationship: transforms_into CCO:B0070223 ! RSF1_HUMAN-Phosphoserine382 relationship: transforms_into CCO:B0070224 ! RSF1_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0070225 ! RSF1_HUMAN-Phosphothreonine496 relationship: transforms_into CCO:B0070226 ! RSF1_HUMAN-Phosphoserine514 relationship: transforms_into CCO:B0070227 ! RSF1_HUMAN-Phosphoserine594 relationship: transforms_into CCO:B0070228 ! RSF1_HUMAN-Phosphoserine612 relationship: transforms_into CCO:B0070229 ! RSF1_HUMAN-Phosphoserine619 relationship: transforms_into CCO:B0070230 ! RSF1_HUMAN-Phosphoserine738 relationship: transforms_into CCO:B0070231 ! RSF1_HUMAN-Phosphoserine768 relationship: transforms_into CCO:B0070232 ! RSF1_HUMAN-Phosphoserine772 relationship: transforms_into CCO:B0070233 ! RSF1_HUMAN-Phosphoserine1086 relationship: transforms_into CCO:B0070234 ! RSF1_HUMAN-Phosphoserine1088 relationship: transforms_into CCO:B0070235 ! RSF1_HUMAN-Phosphoserine1095 relationship: transforms_into CCO:B0070236 ! RSF1_HUMAN-Phosphoserine1211 relationship: transforms_into CCO:B0070237 ! RSF1_HUMAN-Phosphoserine1213 relationship: transforms_into CCO:B0070238 ! RSF1_HUMAN-Phosphoserine1216 relationship: transforms_into CCO:B0070239 ! RSF1_HUMAN-Phosphoserine1267 relationship: transforms_into CCO:B0070240 ! RSF1_HUMAN-Phosphothreonine1268 relationship: transforms_into CCO:B0070241 ! RSF1_HUMAN-Phosphotyrosine1271 relationship: transforms_into CCO:B0070242 ! RSF1_HUMAN-Phosphothreonine1295 relationship: transforms_into CCO:B0070243 ! RSF1_HUMAN-Phosphoserine1315 relationship: transforms_into CCO:B0070244 ! RSF1_HUMAN-Phosphoserine1335 relationship: transforms_into CCO:B0070245 ! RSF1_HUMAN-Phosphoserine1349 relationship: transforms_into CCO:B0070246 ! RSF1_HUMAN-Phosphoserine1354 relationship: transforms_into CCO:B0070247 ! RSF1_HUMAN-Phosphoserine1365 [Term] id: CCO:B0058399 name: Q96T27_HUMAN def: "Ha-Ras1 proto-oncoprotein variant" [UniProtKB:Q96T27] xref: EMBL:AAK56963.1 xref: UniProtKB:Q96T27 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058400 name: RBM15_HUMAN def: "Putative RNA-binding protein 15" [UniProtKB:Q96T37] synonym: "One-twenty two protein" EXACT [UniProtKB:Q96T37] synonym: "RNA-binding motif protein 15" EXACT [UniProtKB:Q96T37] xref: EMBL:AAH06397.2 xref: EMBL:AAH62316.1 xref: EMBL:AAK54722.1 xref: EMBL:AAK54723.1 xref: EMBL:AAK54724.1 xref: EMBL:AAK56920.1 xref: EMBL:BAB14088.1 xref: EMBL:BAB15185.1 xref: EMBL:CAC38828.1 xref: EMBL:CAC38829.1 xref: EMBL:CAC38861.1 xref: EMBL:CAC38862.1 xref: EMBL:CAI19077.1 xref: UniProtKB:Q5D058 xref: UniProtKB:Q5T613 xref: UniProtKB:Q96PE4 xref: UniProtKB:Q96SC5 xref: UniProtKB:Q96SC6 xref: UniProtKB:Q96SC9 xref: UniProtKB:Q96SD0 xref: UniProtKB:Q96T37 xref: UniProtKB:Q96T38 xref: UniProtKB:Q9BRA5 xref: UniProtKB:Q9H6R8 xref: UniProtKB:Q9H9Y0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019646 ! RBM15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069790 ! RBM15_HUMAN-Phosphoserine51 relationship: transforms_into CCO:B0069791 ! RBM15_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0069792 ! RBM15_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0069793 ! RBM15_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0069794 ! RBM15_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0069795 ! RBM15_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0069796 ! RBM15_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0069797 ! RBM15_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0069798 ! RBM15_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0069799 ! RBM15_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0069800 ! RBM15_HUMAN-Phosphothreonine568 relationship: transforms_into CCO:B0069801 ! RBM15_HUMAN-Phosphoserine622 relationship: transforms_into CCO:B0069802 ! RBM15_HUMAN-Phosphoserine656 relationship: transforms_into CCO:B0069803 ! RBM15_HUMAN-Phosphoserine659 relationship: transforms_into CCO:B0069804 ! RBM15_HUMAN-Phosphoserine670 relationship: transforms_into CCO:B0069805 ! RBM15_HUMAN-Phosphoserine674 relationship: transforms_into CCO:B0069806 ! RBM15_HUMAN-Phosphoserine700 relationship: transforms_into CCO:B0069807 ! RBM15_HUMAN-Phosphoserine708 relationship: transforms_into CCO:B0069808 ! RBM15_HUMAN-Phosphoserine724 relationship: transforms_into CCO:B0069809 ! RBM15_HUMAN-Phosphoserine741 relationship: transforms_into CCO:B0069810 ! RBM15_HUMAN-Phosphoserine935 [Term] id: CCO:B0058401 name: PP16B_HUMAN def: "Protein phosphatase 1 regulatory inhibitor subunit 16B" [UniProtKB:Q96T49] synonym: "Ankyrin repeat domain-containing protein 4" EXACT [UniProtKB:Q96T49] synonym: "CAAX box protein TIMAP" EXACT [UniProtKB:Q96T49] synonym: "hTIMAP" EXACT [UniProtKB:Q96T49] synonym: "TGF-beta-inhibited membrane-associated protein" EXACT [UniProtKB:Q96T49] xref: EMBL:AAK52796.1 xref: EMBL:BAA74846.2 xref: EMBL:CAI19080.1 xref: EMBL:CAI20058.1 xref: UniProtKB:O94912 xref: UniProtKB:Q96T49 xref: UniProtKB:Q9NQG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019475 ! PPP1R16B_human relationship: has_function CCO:F0004212 ! protein phosphatase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058402 name: PNKP_HUMAN def: "Bifunctional polynucleotide phosphatase/kinase" [UniProtKB:Q96T60] synonym: "DNA 5'-kinase/3'-phosphatase" EXACT [UniProtKB:Q96T60] synonym: "Polynucleotide kinase-3'-phosphatase" EXACT [UniProtKB:Q96T60] xref: EMBL:AAD47379.1 xref: EMBL:AAD50639.1 xref: EMBL:AAD51135.1 xref: EMBL:AAF44716.1 xref: EMBL:AAH33822.1 xref: EMBL:AAK57340.1 xref: EMBL:AAM82170.1 xref: UniProtKB:Q96T60 xref: UniProtKB:Q9P1V2 xref: UniProtKB:Q9UKU8 xref: UniProtKB:Q9UNF8 xref: UniProtKB:Q9UNI0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019457 ! PNKP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015072 ! krtap4_12-pnkp physical interaction relationship: participates_in CCO:I0015119 ! myoz-pnkp physical interaction relationship: participates_in CCO:I0015444 ! pnkp-trim37 physical interaction relationship: participates_in CCO:I0015512 ! magea11-pnkp physical interaction relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication relationship: transforms_into CCO:B0069430 ! PNKP_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0069431 ! PNKP_HUMAN-Phosphothreonine118 relationship: transforms_into CCO:B0069432 ! PNKP_HUMAN-Phosphothreonine122 relationship: transforms_into CCO:B0069433 ! PNKP_HUMAN-Phosphoserine126 [Term] id: CCO:B0058403 name: MMS19_HUMAN def: "MMS19 nucleotide excision repair protein homolog" [UniProtKB:Q96T76] synonym: "hMMS19" EXACT [UniProtKB:Q96T76] synonym: "MET18 homolog" EXACT [UniProtKB:Q96T76] synonym: "MMS19-like protein" EXACT [UniProtKB:Q96T76] xref: EMBL:AAH02692.1 xref: EMBL:AAH06575.2 xref: EMBL:AAH07298.1 xref: EMBL:AAH09396.2 xref: EMBL:AAH80532.1 xref: EMBL:AAI17130.1 xref: EMBL:AAK52668.1 xref: EMBL:AAK70402.1 xref: EMBL:AAX59033.1 xref: EMBL:BAB55315.1 xref: EMBL:BAB71223.1 xref: EMBL:CAC29239.1 xref: EMBL:CAI14189.1 xref: EMBL:CAI40770.1 xref: UniProtKB:Q17RZ8 xref: UniProtKB:Q5T455 xref: UniProtKB:Q66K82 xref: UniProtKB:Q7L4W8 xref: UniProtKB:Q969Z1 xref: UniProtKB:Q96DF1 xref: UniProtKB:Q96MR1 xref: UniProtKB:Q96RK5 xref: UniProtKB:Q96SK1 xref: UniProtKB:Q96T76 xref: UniProtKB:Q9BUE2 xref: UniProtKB:Q9BYS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018641 ! MMS19_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068243 ! MMS19_HUMAN-Phosphoserine371 [Term] id: CCO:B0058404 name: INSM2_HUMAN def: "Insulinoma-associated protein 2" [UniProtKB:Q96T92] synonym: "Zinc finger protein IA-6" EXACT [UniProtKB:Q96T92] xref: EMBL:AAI30378.1 xref: EMBL:AAI30380.1 xref: EMBL:AAK49393.1 xref: EMBL:BAB69042.1 xref: EMBL:BAC04830.1 xref: EMBL:EAW65872.1 xref: UniProtKB:A1L432 xref: UniProtKB:Q8N8K7 xref: UniProtKB:Q96Q84 xref: UniProtKB:Q96T92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018293 ! INSM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058405 name: Q96TB0_HUMAN def: "Transcription factor T-box 5" [UniProtKB:Q96TB0] xref: EMBL:BAB55448.1 xref: UniProtKB:Q96TB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020198 ! TBX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058406 name: Q99061_HUMAN def: "Guanine nucleotide-binding regulatory protein" [UniProtKB:Q99061] xref: EMBL:AAA52619.1 xref: UniProtKB:Q99061 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0004710 ! GNAI2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058407 name: CSF3R_HUMAN def: "Granulocyte colony-stimulating factor receptor precursor" [UniProtKB:Q99062] synonym: "CD114 antigen" EXACT [UniProtKB:Q99062] synonym: "G-CSF-R" EXACT [UniProtKB:Q99062] xref: EMBL:AAA63176.1 xref: EMBL:AAA63177.1 xref: EMBL:AAA63178.1 xref: EMBL:AAB20660.1 xref: EMBL:AAH53585.1 xref: EMBL:AAN05790.1 xref: EMBL:CAA39252.1 xref: EMBL:CAA39253.1 xref: UniProtKB:Q99062 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017475 ! CSF3R_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058408 name: HTF4_HUMAN def: "Transcription factor 12" [UniProtKB:Q99081] synonym: "DNA-binding protein HTF4" EXACT [UniProtKB:Q99081] synonym: "E-box-binding protein" EXACT [UniProtKB:Q99081] synonym: "Transcription factor HTF-4" EXACT [UniProtKB:Q99081] xref: EMBL:AAA58632.1 xref: EMBL:AAB62389.1 xref: EMBL:AAC37571.1 xref: UniProtKB:Q99081 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018169 ! TCF12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066936 ! HTF4_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0066937 ! HTF4_HUMAN-Phosphoserine47 relationship: transforms_into CCO:B0066938 ! HTF4_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0066939 ! HTF4_HUMAN-Phosphothreonine313 relationship: transforms_into CCO:B0066940 ! HTF4_HUMAN-Phosphoserine333 [Term] id: CCO:B0058409 name: TYBN_HUMAN def: "NB thymosin beta" [UniProtKB:Q99406] synonym: "Thymosin-like protein 8" EXACT [UniProtKB:Q99406] xref: EMBL:AAH00183.1 xref: EMBL:BAA11556.1 xref: EMBL:CAC18959.1 xref: UniProtKB:Q99406 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020393 ! TMSL8_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0002135 ! sequestering of actin monomers relationship: transforms_into CCO:B0071642 ! TYBN_HUMAN-N-acetylserine2 [Term] id: CCO:B0058410 name: CYH2_HUMAN def: "Cytohesin-2" [UniProtKB:Q99418] synonym: "ARF exchange factor" EXACT [UniProtKB:Q99418] synonym: "ARF nucleotide-binding site opener" EXACT [UniProtKB:Q99418] synonym: "PH, SEC7 and coiled-coil domain-containing protein 2" EXACT [UniProtKB:Q99418] synonym: "Protein ARNO" EXACT [UniProtKB:Q99418] xref: EMBL:AAB09591.1 xref: EMBL:AAH04361.1 xref: EMBL:AAH38713.1 xref: EMBL:CAA68084.1 xref: UniProtKB:Q8IXY9 xref: UniProtKB:Q92958 xref: UniProtKB:Q99418 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017510 ! CYTH2_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015160 ! jm11-pscd2 physical interaction relationship: participates_in CCO:I0015899 ! arf1-pscd2-1 physical interaction relationship: participates_in CCO:I0015900 ! arf1-pscd2-2 physical interaction relationship: participates_in CCO:I0018148 ! arf1-pscd2-3 direct interaction relationship: participates_in CCO:I0018149 ! arf1-pscd2-4 direct interaction relationship: participates_in CCO:I0018881 ! pscd2-atp6v0a2-6 physical interaction relationship: participates_in CCO:I0019519 ! pscd2-atp6v0a2-7 physical interaction relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0058411 name: Q99419_HUMAN def: "ICSAT transcription factor" [UniProtKB:Q99419] xref: EMBL:BAA11335.1 xref: UniProtKB:Q99419 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002274 ! positive regulation of interleukin-10 biosynthetic process relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002309 ! positive regulation of interleukin-13 biosynthetic process relationship: participates_in CCO:P0002345 ! positive regulation of interleukin-4 biosynthetic process relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0058412 name: PHX2B_HUMAN def: "Paired mesoderm homeobox protein 2B" [UniProtKB:Q99453] synonym: "NBPhox" EXACT [UniProtKB:Q99453] synonym: "Neuroblastoma Phox" EXACT [UniProtKB:Q99453] synonym: "Paired-like homeobox 2B" EXACT [UniProtKB:Q99453] synonym: "PHOX2B homeodomain protein" EXACT [UniProtKB:Q99453] xref: EMBL:AAD26698.1 xref: EMBL:AAH17199.1 xref: EMBL:BAA11555.1 xref: EMBL:BAA82670.1 xref: UniProtKB:Q6PJD9 xref: UniProtKB:Q99453 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019390 ! PHOX2B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058413 name: NPY6R_HUMAN def: "Putative neuropeptide Y receptor type 6" [UniProtKB:Q99463] synonym: "NPY Y1-like receptor" EXACT [UniProtKB:Q99463] synonym: "NPY6-R" EXACT [UniProtKB:Q99463] synonym: "PP2" EXACT [UniProtKB:Q99463] synonym: "Putative pancreatic polypeptide receptor 2" EXACT [UniProtKB:Q99463] xref: EMBL:BAA13103.1 xref: EMBL:EAW62180.1 xref: UniProtKB:Q99463 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022455 ! NPY6R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058414 name: NOTC4_HUMAN def: "Neurogenic locus notch homolog protein 4 precursor" [UniProtKB:Q99466] synonym: "hNotch4" EXACT [UniProtKB:Q99466] synonym: "Notch 4" EXACT [UniProtKB:Q99466] xref: EMBL:AAC32288.1 xref: EMBL:AAC63097.1 xref: EMBL:BAA09708.1 xref: EMBL:BAA13116.1 xref: EMBL:BAA88951.1 xref: EMBL:BAA88952.1 xref: EMBL:BAB20317.1 xref: UniProtKB:O00306 xref: UniProtKB:Q99458 xref: UniProtKB:Q99466 xref: UniProtKB:Q99940 xref: UniProtKB:Q9H3S8 xref: UniProtKB:Q9UII9 xref: UniProtKB:Q9UIJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008797 ! NOTCH4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008012 ! advanced glycation end-product receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation relationship: participates_in CCO:P0002416 ! negative regulation of endothelial cell differentiation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0058415 name: STAC_HUMAN def: "SH3 and cysteine-rich domain-containing protein" [UniProtKB:Q99469] synonym: "SRC homology 3 and cysteine-rich domain protein" EXACT [UniProtKB:Q99469] xref: EMBL:BAA13152.1 xref: UniProtKB:Q99469 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020062 ! STAC_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058416 name: PFD5_HUMAN def: "Prefoldin subunit 5" [UniProtKB:Q99471] synonym: "C-myc-binding protein Mm-1" EXACT [UniProtKB:Q99471] synonym: "Myc modulator 1" EXACT [UniProtKB:Q99471] xref: EMBL:AAH62671.1 xref: EMBL:AAP35859.1 xref: EMBL:BAA14006.1 xref: EMBL:BAB32643.1 xref: EMBL:BAB32644.1 xref: UniProtKB:Q54AA8 xref: UniProtKB:Q99471 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019374 ! PFDN5_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058417 name: CENG1_HUMAN def: "Centaurin-gamma-1" [UniProtKB:Q99490] synonym: "AGAP-2" EXACT [UniProtKB:Q99490] synonym: "ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2" EXACT [UniProtKB:Q99490] synonym: "GGAP2" EXACT [UniProtKB:Q99490] synonym: "GTP-binding and GTPase-activating protein 2" EXACT [UniProtKB:Q99490] synonym: "Phosphatidylinositol-3-kinase enhancer" EXACT [UniProtKB:Q99490] synonym: "PIKE" EXACT [UniProtKB:Q99490] xref: EMBL:AAC39522.2 xref: EMBL:AAH28020.1 xref: EMBL:AAL04171.1 xref: EMBL:AAM97540.1 xref: EMBL:AAO39848.1 xref: EMBL:BAA11484.2 xref: UniProtKB:O00578 xref: UniProtKB:Q548E0 xref: UniProtKB:Q8IWU3 xref: UniProtKB:Q99490 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017331 ! CENTG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0064264 ! CENG1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0064265 ! CENG1_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0064266 ! CENG1_HUMAN-Phosphoserine638 relationship: transforms_into CCO:B0064267 ! CENG1_HUMAN-Phosphoserine808 relationship: transforms_into CCO:B0064268 ! CENG1_HUMAN-Phosphoserine865 relationship: transforms_into CCO:B0064269 ! CENG1_HUMAN-Phosphoserine927 [Term] id: CCO:B0058418 name: S1PR3_HUMAN def: "Sphingosine 1-phosphate receptor 3" [UniProtKB:Q99500] synonym: "Endothelial differentiation G-protein coupled receptor 3" EXACT [UniProtKB:Q99500] synonym: "S1P receptor 3" EXACT [UniProtKB:Q99500] synonym: "S1P receptor Edg-3" EXACT [UniProtKB:Q99500] synonym: "S1P3" EXACT [UniProtKB:Q99500] synonym: "Sphingosine 1-phosphate receptor Edg-3" EXACT [UniProtKB:Q99500] xref: EMBL:AAC51906.1 xref: EMBL:AAH60827.1 xref: EMBL:AAH69579.1 xref: EMBL:AAP84353.1 xref: EMBL:BAG35658.1 xref: EMBL:CAA58744.1 xref: EMBL:CAI16743.1 xref: EMBL:EAW62758.1 xref: UniProtKB:Q5SQD8 xref: UniProtKB:Q7Z5I2 xref: UniProtKB:Q99500 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022626 ! S1PR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0058419 name: EYA1_HUMAN def: "Eyes absent homolog 1" [UniProtKB:Q99502] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q99502] xref: EMBL:AAI21800.1 xref: EMBL:CAA03922.1 xref: EMBL:CAA03923.1 xref: EMBL:CAA71309.1 xref: UniProtKB:A6NHQ0 xref: UniProtKB:Q0P516 xref: UniProtKB:Q99502 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017746 ! EYA1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058420 name: EYA3_HUMAN def: "Eyes absent homolog 3" [UniProtKB:Q99504] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q99504] xref: EMBL:AAB42066.1 xref: EMBL:CAA07814.1 xref: EMBL:CAA71311.1 xref: UniProtKB:O95463 xref: UniProtKB:Q99504 xref: UniProtKB:Q99813 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017748 ! EYA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065185 ! EYA3_HUMAN-Phosphoserine266 [Term] id: CCO:B0058421 name: SORT_HUMAN def: "Sortilin precursor" [UniProtKB:Q99523] synonym: "100 kDa NT receptor" EXACT [UniProtKB:Q99523] synonym: "Glycoprotein 95" EXACT [UniProtKB:Q99523] synonym: "Gp95" EXACT [UniProtKB:Q99523] synonym: "Neurotensin receptor 3" EXACT [UniProtKB:Q99523] synonym: "NT3" EXACT [UniProtKB:Q99523] synonym: "NTR3" EXACT [UniProtKB:Q99523] xref: EMBL:AAH23542.1 xref: EMBL:CAA66904.2 xref: EMBL:CAI13180.1 xref: UniProtKB:Q8IZ49 xref: UniProtKB:Q99523 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019986 ! SORT1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002502 ! nerve growth factor receptor activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004423 ! neurotensin receptor activity, non-G-protein coupled relationship: has_function CCO:F0007336 ! nerve growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000981 ! clathrin-coated vesicle relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: located_in CCO:C0001358 ! nuclear membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0000947 ! regulation of gene expression relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002757 ! nerve growth factor receptor signaling pathway relationship: transforms_into CCO:B0070745 ! SORT_HUMAN-Phosphoserine825 [Term] id: CCO:B0058422 name: GPER_HUMAN def: "G-protein coupled estrogen receptor 1" [UniProtKB:Q99527] synonym: "Chemokine receptor-like 2" EXACT [UniProtKB:Q99527] synonym: "FEG-1" EXACT [UniProtKB:Q99527] synonym: "Flow-induced endothelial G-protein coupled receptor 1" EXACT [UniProtKB:Q99527] synonym: "G-protein coupled receptor 30" EXACT [UniProtKB:Q99527] synonym: "GPCR-BR" EXACT [UniProtKB:Q99527] synonym: "IL8-related receptor DRY12" EXACT [UniProtKB:Q99527] synonym: "LYGPR" EXACT [UniProtKB:Q99527] synonym: "Lymphocyte-derived G-protein coupled receptor" EXACT [UniProtKB:Q99527] synonym: "Membrane estrogen receptor" EXACT [UniProtKB:Q99527] synonym: "mER" EXACT [UniProtKB:Q99527] xref: EMBL:AAB02736.1 xref: EMBL:AAB88017.1 xref: EMBL:AAC51173.1 xref: EMBL:AAC51904.1 xref: EMBL:AAC52027.1 xref: EMBL:AAH11634.1 xref: EMBL:CAA67133.1 xref: EMBL:CAA69354.1 xref: EMBL:CAG46541.1 xref: EMBL:EAL23938.1 xref: UniProtKB:O00143 xref: UniProtKB:O43494 xref: UniProtKB:Q13631 xref: UniProtKB:Q6FHL1 xref: UniProtKB:Q96F42 xref: UniProtKB:Q99527 xref: UniProtKB:Q99981 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018000 ! GPER_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058423 name: P2RX4_HUMAN def: "P2X purinoceptor 4" [UniProtKB:Q99571] synonym: "ATP receptor" EXACT [UniProtKB:Q99571] synonym: "P2X4" EXACT [UniProtKB:Q99571] synonym: "Purinergic receptor" EXACT [UniProtKB:Q99571] xref: EMBL:AAB58405.1 xref: EMBL:AAB66834.1 xref: EMBL:AAD00553.1 xref: EMBL:AAD00556.1 xref: EMBL:AAF06661.1 xref: EMBL:CAA68948.1 xref: UniProtKB:O00450 xref: UniProtKB:O14722 xref: UniProtKB:Q99571 xref: UniProtKB:Q9UBG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019261 ! P2RX4_human relationship: has_function CCO:F0000165 ! purinergic nucleotide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001273 ! ATP-gated cation channel activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002368 ! positive regulation of nitric oxide biosynthetic process relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling relationship: transforms_into CCO:B0069013 ! P2RX4_HUMAN-Phosphotyrosine378 [Term] id: CCO:B0058424 name: P2RX7_HUMAN def: "P2X purinoceptor 7" [UniProtKB:Q99572] synonym: "ATP receptor" EXACT [UniProtKB:Q99572] synonym: "P2X7" EXACT [UniProtKB:Q99572] synonym: "P2Z receptor" EXACT [UniProtKB:Q99572] synonym: "Purinergic receptor" EXACT [UniProtKB:Q99572] xref: EMBL:AAH11913.1 xref: EMBL:CAA70755.1 xref: EMBL:CAA73360.1 xref: UniProtKB:O14991 xref: UniProtKB:Q96EV7 xref: UniProtKB:Q99572 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019264 ! P2RX7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002210 ! negative regulation of MAPKKK cascade relationship: participates_in CCO:P0002614 ! positive regulation of cytolysis relationship: participates_in CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis relationship: transforms_into CCO:B0069016 ! P2RX7_HUMAN-Phosphotyrosine343 [Term] id: CCO:B0058425 name: T22D3_HUMAN def: "TSC22 domain family protein 3" [UniProtKB:Q99576] synonym: "Delta sleep-inducing peptide immunoreactor" EXACT [UniProtKB:Q99576] synonym: "DSIP-immunoreactive peptide" EXACT [UniProtKB:Q99576] synonym: "Glucocorticoid-induced leucine zipper protein" EXACT [UniProtKB:Q99576] synonym: "hDIP" EXACT [UniProtKB:Q99576] synonym: "Protein DIP" EXACT [UniProtKB:Q99576] synonym: "TSC-22-like protein" EXACT [UniProtKB:Q99576] synonym: "TSC-22R" EXACT [UniProtKB:Q99576] xref: EMBL:AAD41085.1 xref: EMBL:AAD56234.1 xref: EMBL:AAG12456.1 xref: EMBL:AAH18148.3 xref: EMBL:AAH72446.1 xref: EMBL:BAB18680.1 xref: EMBL:BAC03934.1 xref: EMBL:CAA90644.1 xref: EMBL:CAB53669.1 xref: EMBL:CAG38481.1 xref: EMBL:CAI45951.1 xref: UniProtKB:Q5H9S3 xref: UniProtKB:Q6FIH6 xref: UniProtKB:Q8NAI1 xref: UniProtKB:Q8WVB9 xref: UniProtKB:Q99576 xref: UniProtKB:Q9UBN5 xref: UniProtKB:Q9UG13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020089 ! TSC22D3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015571 ! plekhf2-tsc22d3 physical interaction relationship: participates_in CCO:I0015736 ! hpcal4-tsc22d3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071065 ! T22D3_HUMAN-Phosphoserine122 [Term] id: CCO:B0058426 name: RIT2_HUMAN def: "GTP-binding protein Rit2" [UniProtKB:Q99578] synonym: "Ras-like protein expressed in neurons" EXACT [UniProtKB:Q99578] synonym: "Ras-like without CAAX protein 2" EXACT [UniProtKB:Q99578] xref: EMBL:AAB42214.1 xref: EMBL:AAB64245.1 xref: EMBL:AAB64247.1 xref: EMBL:AAH18060.1 xref: EMBL:AAM12636.1 xref: EMBL:AAS75332.1 xref: EMBL:CAA68850.1 xref: UniProtKB:O15295 xref: UniProtKB:Q8TD69 xref: UniProtKB:Q8WVF6 xref: UniProtKB:Q92964 xref: UniProtKB:Q99578 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019747 ! RIT2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0017308 ! rlg1-rit2 physical interaction relationship: participates_in CCO:I0018587 ! rit2-af6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058427 name: FEV_HUMAN def: "Protein FEV" [UniProtKB:Q99581] synonym: "Fifth Ewing variant protein" EXACT [UniProtKB:Q99581] synonym: "PC12 ETS domain-containing transcription factor 1" EXACT [UniProtKB:Q99581] synonym: "PC12 ETS factor 1" EXACT [UniProtKB:Q99581] synonym: "Pet-1" EXACT [UniProtKB:Q99581] xref: EMBL:AAH23511.1 xref: EMBL:AAX88917.1 xref: EMBL:CAA70169.1 xref: EMBL:EAW70664.1 xref: UniProtKB:Q99581 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022254 ! FEV_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058428 name: ZN238_HUMAN def: "Zinc finger protein 238" [UniProtKB:Q99592] synonym: "58 kDa repressor protein" EXACT [UniProtKB:Q99592] synonym: "TAZ-1" EXACT [UniProtKB:Q99592] synonym: "Transcriptional repressor RP58" EXACT [UniProtKB:Q99592] synonym: "Translin-associated zinc finger protein 1" EXACT [UniProtKB:Q99592] synonym: "Zinc finger and BTB domain-containing protein 18" EXACT [UniProtKB:Q99592] synonym: "Zinc finger protein C2H2-171" EXACT [UniProtKB:Q99592] xref: EMBL:AAA81368.1 xref: EMBL:AAH36677.2 xref: EMBL:CAA04718.1 xref: EMBL:CAA11262.1 xref: EMBL:CAA64468.1 xref: EMBL:CAH71954.2 xref: UniProtKB:Q13397 xref: UniProtKB:Q5VU40 xref: UniProtKB:Q8N463 xref: UniProtKB:Q99592 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020675 ! ZNF238_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072071 ! ZN238_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0072072 ! ZN238_HUMAN-Phosphoserine517 [Term] id: CCO:B0058429 name: TBX5_HUMAN def: "T-box transcription factor TBX5" [UniProtKB:Q99593] synonym: "T-box protein 5" EXACT [UniProtKB:Q99593] xref: EMBL:AAC04619.1 xref: EMBL:AAC51644.1 xref: EMBL:AAF34659.1 xref: EMBL:AAH27942.1 xref: EMBL:CAA70592.1 xref: UniProtKB:O15301 xref: UniProtKB:Q99593 xref: UniProtKB:Q9Y4I2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020198 ! TBX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0003152 ! positive regulation of cardioblast differentiation relationship: participates_in CCO:P0003233 ! negative regulation of cardiac muscle cell proliferation [Term] id: CCO:B0058430 name: ELF4_HUMAN def: "ETS-related transcription factor Elf-4" [UniProtKB:Q99607] synonym: "E74-like factor 4" EXACT [UniProtKB:Q99607] synonym: "Myeloid Elf-1-like factor" EXACT [UniProtKB:Q99607] xref: EMBL:AAB53693.1 xref: EMBL:AAC17452.1 xref: EMBL:AAH17194.1 xref: EMBL:CAI42371.1 xref: EMBL:CAI42882.1 xref: UniProtKB:O60435 xref: UniProtKB:Q99607 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017684 ! ELF4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018091 ! mef-aml1-1 physical interaction relationship: participates_in CCO:P0000471 ! natural killer cell proliferation relationship: participates_in CCO:P0000482 ! NK T cell proliferation relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0064978 ! ELF4_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0064979 ! ELF4_HUMAN-Phosphothreonine643 relationship: transforms_into CCO:B0064980 ! ELF4_HUMAN-Phosphoserine648 [Term] id: CCO:B0058431 name: KLF6_HUMAN def: "Krueppel-like factor 6" [UniProtKB:Q99612] synonym: "B-cell-derived protein 1" EXACT [UniProtKB:Q99612] synonym: "Core promoter element-binding protein" EXACT [UniProtKB:Q99612] synonym: "GC-rich sites-binding factor GBF" EXACT [UniProtKB:Q99612] synonym: "Proto-oncogene BCD1" EXACT [UniProtKB:Q99612] synonym: "Transcription factor Zf9" EXACT [UniProtKB:Q99612] xref: EMBL:AAC23699.1 xref: EMBL:AAC39929.1 xref: EMBL:AAH00311.1 xref: EMBL:AAM73548.1 xref: EMBL:AAP35424.1 xref: EMBL:BAA33050.1 xref: EMBL:CAH71010.1 xref: EMBL:CAH71011.1 xref: EMBL:CAH74049.1 xref: EMBL:CAH74050.1 xref: UniProtKB:Q5VUT7 xref: UniProtKB:Q5VUT8 xref: UniProtKB:Q99612 xref: UniProtKB:Q9BT79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018421 ! KLF6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015401 ! ehmt2-klf6 physical interaction relationship: participates_in CCO:I0019950 ! klf6-apom physical interaction relationship: participates_in CCO:I0019951 ! klf6-gtf3c1 physical interaction relationship: participates_in CCO:I0019952 ! klf6-loc56902 physical interaction relationship: participates_in CCO:I0019953 ! klf6-pola2 physical interaction relationship: participates_in CCO:I0020528 ! celsr2-klf6 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058432 name: PHB2_HUMAN def: "Prohibitin-2" [UniProtKB:Q99623] synonym: "B-cell receptor-associated protein BAP37" EXACT [UniProtKB:Q99623] synonym: "D-prohibitin" EXACT [UniProtKB:Q99623] synonym: "Repressor of estrogen receptor activity" EXACT [UniProtKB:Q99623] xref: EMBL:AAB51324.1 xref: EMBL:AAC51639.1 xref: EMBL:AAD38042.1 xref: EMBL:AAF17231.1 xref: EMBL:AAF44345.1 xref: EMBL:AAH14766.1 xref: EMBL:AAI10323.1 xref: UniProtKB:Q2YDA4 xref: UniProtKB:Q7KYU3 xref: UniProtKB:Q92978 xref: UniProtKB:Q99623 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019377 ! PHB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0069245 ! PHB2_HUMAN-Phosphotyrosine128 relationship: transforms_into CCO:B0069246 ! PHB2_HUMAN-Phosphotyrosine248 [Term] id: CCO:B0058433 name: Q99642_HUMAN def: "GRP/bombesin receptor" [UniProtKB:Q99642] xref: EMBL:AAB40612.1 xref: UniProtKB:Q99642 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001288 ! bombesin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058434 name: OSMR_HUMAN def: "Oncostatin-M specific receptor subunit beta precursor" [UniProtKB:Q99650] xref: EMBL:AAC50946.1 xref: EMBL:AAH10943.1 xref: EMBL:AAH63468.1 xref: EMBL:AAI25210.1 xref: EMBL:AAI25211.1 xref: UniProtKB:Q6P4E8 xref: UniProtKB:Q96QJ6 xref: UniProtKB:Q99650 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019241 ! OSMR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0068995 ! OSMR_HUMAN-Phosphoserine826 relationship: transforms_into CCO:B0068996 ! OSMR_HUMAN-Phosphotyrosine837 relationship: transforms_into CCO:B0068997 ! OSMR_HUMAN-Phosphoserine889 [Term] id: CCO:B0058435 name: CHP1_HUMAN def: "Calcium-binding protein p22" [UniProtKB:Q99653] synonym: "Calcineurin B homolog" EXACT [UniProtKB:Q99653] synonym: "Calcineurin homologous protein" EXACT [UniProtKB:Q99653] synonym: "Calcium-binding protein CHP" EXACT [UniProtKB:Q99653] xref: EMBL:AAB37770.1 xref: EMBL:AAH31293.1 xref: EMBL:CAG38776.1 xref: EMBL:CAG46882.1 xref: EMBL:EAW92474.1 xref: UniProtKB:Q6FHZ9 xref: UniProtKB:Q99653 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017357 ! CHP_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0002867 ! potassium channel regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058436 name: Q99662_HUMAN def: "Tyrosine-protein kinase receptor" [UniProtKB:Q99662] synonym: "EC 2.7.10.1" EXACT [UniProtKB:Q99662] xref: EMBL:AAC50969.1 xref: EMBL:BAG64945.1 xref: UniProtKB:Q99662 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018406 ! KIT_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0058437 name: ZN184_HUMAN def: "Zinc finger protein 184" [UniProtKB:Q99676] xref: EMBL:AAC51180.1 xref: EMBL:AAH22992.1 xref: EMBL:BAG35662.1 xref: EMBL:CAA17278.1 xref: UniProtKB:B2R715 xref: UniProtKB:O60792 xref: UniProtKB:Q8TBA9 xref: UniProtKB:Q99676 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020644 ! ZNF184_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058438 name: GPR20_HUMAN def: "Probable G-protein coupled receptor 20" [UniProtKB:Q99678] xref: EMBL:AAC51302.1 xref: UniProtKB:Q99678 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018008 ! GPR20_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058439 name: GPR21_HUMAN def: "Probable G-protein coupled receptor 21" [UniProtKB:Q99679] xref: EMBL:AAC51303.1 xref: EMBL:AAH66885.2 xref: EMBL:AAH66886.2 xref: EMBL:AAH67532.2 xref: EMBL:AAH67533.2 xref: UniProtKB:Q6NXU2 xref: UniProtKB:Q99679 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018009 ! GPR21_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058440 name: GPR22_HUMAN def: "Probable G-protein coupled receptor 22" [UniProtKB:Q99680] xref: EMBL:AAB63815.1 xref: EMBL:AAC51304.1 xref: UniProtKB:O14554 xref: UniProtKB:Q99680 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018010 ! GPR22_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058441 name: PITX2_HUMAN def: "Pituitary homeobox 2" [UniProtKB:Q99697] synonym: "ALL1-responsive protein ARP1" EXACT [UniProtKB:Q99697] synonym: "RIEG bicoid-related homeobox transcription factor" EXACT [UniProtKB:Q99697] synonym: "Solurshin" EXACT [UniProtKB:Q99697] xref: EMBL:AAC16257.1 xref: EMBL:AAC39716.1 xref: EMBL:AAC39717.1 xref: EMBL:AAC39718.1 xref: EMBL:AAH13998.1 xref: EMBL:AAK15048.1 xref: UniProtKB:O60578 xref: UniProtKB:O60579 xref: UniProtKB:O60580 xref: UniProtKB:Q99697 xref: UniProtKB:Q9BY17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019403 ! PITX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058442 name: LYST_HUMAN def: "Lysosomal-trafficking regulator" [UniProtKB:Q99698] synonym: "Beige homolog" EXACT [UniProtKB:Q99698] xref: EMBL:AAB39697.1 xref: EMBL:AAB41309.1 xref: EMBL:AAB41533.1 xref: EMBL:AAB51608.1 xref: EMBL:AAB87737.1 xref: EMBL:CAI14952.1 xref: EMBL:CAI18987.1 xref: UniProtKB:O43274 xref: UniProtKB:Q5T2U9 xref: UniProtKB:Q96TD7 xref: UniProtKB:Q96TD8 xref: UniProtKB:Q99698 xref: UniProtKB:Q99709 xref: UniProtKB:Q9H133 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018537 ! LYST_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002050 ! natural killer cell mediated cytotoxicity relationship: transforms_into CCO:B0067803 ! LYST_HUMAN-Phosphoserine2213 relationship: transforms_into CCO:B0067804 ! LYST_HUMAN-Phosphoserine2217 [Term] id: CCO:B0058443 name: DOK1_HUMAN def: "Docking protein 1" [UniProtKB:Q99704] synonym: "Downstream of tyrosine kinase 1" EXACT [UniProtKB:Q99704] synonym: "p62(dok)" EXACT [UniProtKB:Q99704] synonym: "pp62" EXACT [UniProtKB:Q99704] xref: EMBL:AAB88182.1 xref: EMBL:AAC51127.1 xref: EMBL:AAF19167.1 xref: EMBL:AAI14441.1 xref: EMBL:AAX93224.1 xref: UniProtKB:O43204 xref: UniProtKB:Q53TY2 xref: UniProtKB:Q99704 xref: UniProtKB:Q9UHG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017601 ! DOK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: transforms_into CCO:B0064832 ! DOK1_HUMAN-Phosphoserine269 relationship: transforms_into CCO:B0064833 ! DOK1_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0064834 ! DOK1_HUMAN-Phosphoserine291 relationship: transforms_into CCO:B0064835 ! DOK1_HUMAN-Phosphotyrosine296 relationship: transforms_into CCO:B0064836 ! DOK1_HUMAN-Phosphotyrosine315 relationship: transforms_into CCO:B0064837 ! DOK1_HUMAN-Phosphotyrosine337 relationship: transforms_into CCO:B0064838 ! DOK1_HUMAN-Phosphotyrosine341 relationship: transforms_into CCO:B0064839 ! DOK1_HUMAN-Phosphotyrosine362 relationship: transforms_into CCO:B0064840 ! DOK1_HUMAN-Phosphotyrosine377 relationship: transforms_into CCO:B0064841 ! DOK1_HUMAN-Phosphotyrosine398 relationship: transforms_into CCO:B0064842 ! DOK1_HUMAN-Phosphotyrosine402 relationship: transforms_into CCO:B0064843 ! DOK1_HUMAN-Phosphotyrosine409 relationship: transforms_into CCO:B0064844 ! DOK1_HUMAN-Phosphotyrosine449 [Term] id: CCO:B0058444 name: MCHR1_HUMAN def: "Melanin-concentrating hormone receptor 1" [UniProtKB:Q99705] synonym: "G-protein coupled receptor 24" EXACT [UniProtKB:Q99705] synonym: "MCH receptor 1" EXACT [UniProtKB:Q99705] synonym: "MCH-1R" EXACT [UniProtKB:Q99705] synonym: "MCH-R1" EXACT [UniProtKB:Q99705] synonym: "MCH1R" EXACT [UniProtKB:Q99705] synonym: "MCHR" EXACT [UniProtKB:Q99705] synonym: "MCHR-1" EXACT [UniProtKB:Q99705] synonym: "SLC-1" EXACT [UniProtKB:Q99705] synonym: "Somatostatin receptor-like protein" EXACT [UniProtKB:Q99705] xref: EMBL:AAC14587.1 xref: EMBL:AAH01736.1 xref: EMBL:AAH21146.1 xref: EMBL:AAO14670.1 xref: EMBL:AAP35371.1 xref: EMBL:AAS72373.1 xref: EMBL:BAB60890.1 xref: EMBL:CAG30383.1 xref: EMBL:CAI17933.1 xref: UniProtKB:Q5R3J1 xref: UniProtKB:Q96S47 xref: UniProtKB:Q99705 xref: UniProtKB:Q9BV08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018587 ! MCHR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_function CCO:F0004369 ! melanin-concentrating hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001281 ! nonmotile primary cilium relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0058445 name: KI2L4_HUMAN def: "Killer cell immunoglobulin-like receptor 2DL4 precursor" [UniProtKB:Q99706] synonym: "CD158 antigen-like family member D" EXACT [UniProtKB:Q99706] synonym: "CD158d antigen" EXACT [UniProtKB:Q99706] synonym: "G9P" EXACT [UniProtKB:Q99706] synonym: "Killer cell inhibitory receptor 103AS" EXACT [UniProtKB:Q99706] synonym: "KIR-103AS" EXACT [UniProtKB:Q99706] synonym: "MHC class I NK cell receptor KIR103AS" EXACT [UniProtKB:Q99706] xref: EMBL:AAB49756.1 xref: EMBL:AAB61926.1 xref: EMBL:AAB71387.1 xref: EMBL:AAB71388.1 xref: EMBL:AAB71389.1 xref: EMBL:AAB71390.1 xref: EMBL:AAB95164.1 xref: EMBL:AAB95165.1 xref: EMBL:AAB95166.1 xref: EMBL:AAC51146.1 xref: EMBL:AAD24763.1 xref: EMBL:CAA65868.1 xref: EMBL:CAA67842.1 xref: EMBL:CAA67843.1 xref: EMBL:CAA67844.1 xref: UniProtKB:O14621 xref: UniProtKB:O14622 xref: UniProtKB:O14623 xref: UniProtKB:O14624 xref: UniProtKB:O43534 xref: UniProtKB:P78400 xref: UniProtKB:P78401 xref: UniProtKB:Q99559 xref: UniProtKB:Q99560 xref: UniProtKB:Q99561 xref: UniProtKB:Q99562 xref: UniProtKB:Q99706 xref: UniProtKB:Q9UQJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018402 ! KIR2DL4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058446 name: SMAD5_HUMAN def: "Mothers against decapentaplegic homolog 5" [UniProtKB:Q99717] synonym: "hSmad5" EXACT [UniProtKB:Q99717] synonym: "JV5-1" EXACT [UniProtKB:Q99717] synonym: "Mothers against DPP homolog 5" EXACT [UniProtKB:Q99717] synonym: "SMAD 5" EXACT [UniProtKB:Q99717] synonym: "Smad5" EXACT [UniProtKB:Q99717] xref: EMBL:AAB66353.1 xref: EMBL:AAB72180.1 xref: EMBL:AAB82655.1 xref: EMBL:AAB92396.1 xref: EMBL:AAB95090.1 xref: EMBL:AAC50791.1 xref: EMBL:AAH09682.1 xref: UniProtKB:O14688 xref: UniProtKB:Q15798 xref: UniProtKB:Q99717 xref: UniProtKB:Q9UQA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019940 ! SMAD5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070603 ! SMAD5_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0070604 ! SMAD5_HUMAN-Phosphoserine463 relationship: transforms_into CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 [Term] id: CCO:B0058447 name: ROAA_HUMAN def: "Heterogeneous nuclear ribonucleoprotein A/B" [UniProtKB:Q99729] synonym: "ABBP-1" EXACT [UniProtKB:Q99729] synonym: "APOBEC1-binding protein 1" EXACT [UniProtKB:Q99729] synonym: "hnRNP A/B" EXACT [UniProtKB:Q99729] xref: EMBL:AAA36575.1 xref: EMBL:AAC50956.1 xref: EMBL:AAH01616.1 xref: EMBL:AAH02625.1 xref: EMBL:AAH04561.1 xref: EMBL:AAH09359.1 xref: EMBL:AAH36708.1 xref: EMBL:BAC05134.1 xref: UniProtKB:Q04150 xref: UniProtKB:Q8N7U3 xref: UniProtKB:Q99729 xref: UniProtKB:Q9BQ99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019761 ! HNRNPAB_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000480 ! epithelial to mesenchymal transition relationship: participates_in CCO:P0002172 ! positive regulation of gene-specific transcription relationship: transforms_into CCO:B0070121 ! ROAA_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0070122 ! ROAA_HUMAN-Phosphoserine242 relationship: transforms_into CCO:B0070123 ! ROAA_HUMAN-Omega-N-methylated arginine322 [Term] id: CCO:B0058448 name: CCL19_HUMAN def: "C-C motif chemokine 19 precursor" [UniProtKB:Q99731] synonym: "Beta chemokine exodus-3" EXACT [UniProtKB:Q99731] synonym: "CK beta-11" EXACT [UniProtKB:Q99731] synonym: "EBI1-ligand chemokine" EXACT [UniProtKB:Q99731] synonym: "ELC" EXACT [UniProtKB:Q99731] synonym: "Macrophage inflammatory protein 3 beta" EXACT [UniProtKB:Q99731] synonym: "MIP-3-beta" EXACT [UniProtKB:Q99731] synonym: "Small-inducible cytokine A19" EXACT [UniProtKB:Q99731] xref: EMBL:AAC23905.1 xref: EMBL:AAC50944.1 xref: EMBL:AAH27968.1 xref: EMBL:BAA20383.1 xref: EMBL:CAA11307.1 xref: UniProtKB:O00697 xref: UniProtKB:O00736 xref: UniProtKB:Q99731 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017263 ! CCL19_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058449 name: LITAF_HUMAN def: "Lipopolysaccharide-induced tumor necrosis factor-alpha factor" [UniProtKB:Q99732] synonym: "LPS-induced TNF-alpha factor" EXACT [UniProtKB:Q99732] synonym: "p53-induced gene 7 protein" EXACT [UniProtKB:Q99732] synonym: "Small integral membrane protein of lysosome/late endosome" EXACT [UniProtKB:Q99732] xref: EMBL:AAB36550.1 xref: EMBL:AAC39530.1 xref: EMBL:AAH00053.1 xref: EMBL:AAH08309.1 xref: EMBL:AAH16491.1 xref: EMBL:AAH39840.1 xref: EMBL:AAH46154.1 xref: EMBL:AAH96063.1 xref: EMBL:AAH96065.1 xref: EMBL:AAH96066.1 xref: EMBL:AAI01402.1 xref: EMBL:AAI01403.1 xref: EMBL:AAI01970.1 xref: EMBL:BAB32547.1 xref: EMBL:CAD97778.1 xref: UniProtKB:Q05DW0 xref: UniProtKB:Q99732 xref: UniProtKB:Q9C0L6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018502 ! LITAF_human relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007999 ! WW domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020582 ! litaf-comt physical interaction relationship: participates_in CCO:I0020583 ! litaf-flj10324 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058450 name: MGST2_HUMAN def: "Microsomal glutathione S-transferase 2" [UniProtKB:Q99735] synonym: "EC 2.5.1.18" EXACT [UniProtKB:Q99735] synonym: "Microsomal GST-2" EXACT [UniProtKB:Q99735] synonym: "Microsomal GST-II" EXACT [UniProtKB:Q99735] xref: EMBL:AAC51768.1 xref: EMBL:AAH25416.1 xref: EMBL:AAP88934.1 xref: EMBL:CAG28568.1 xref: UniProtKB:Q7Z5B8 xref: UniProtKB:Q99735 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018612 ! MGST2_human relationship: has_function CCO:F0000783 ! glutathione transferase activity relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058451 name: NPAS1_HUMAN def: "Neuronal PAS domain-containing protein 1" [UniProtKB:Q99742] synonym: "Basic-helix-loop-helix-PAS protein MOP5" EXACT [UniProtKB:Q99742] synonym: "Member of PAS protein 5" EXACT [UniProtKB:Q99742] synonym: "Neuronal PAS1" EXACT [UniProtKB:Q99742] xref: EMBL:AAB47248.1 xref: EMBL:AAC51214.1 xref: EMBL:AAH39016.1 xref: EMBL:BAB21098.1 xref: UniProtKB:Q99632 xref: UniProtKB:Q99742 xref: UniProtKB:Q9BY83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018827 ! NPAS1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058452 name: SNAG_HUMAN def: "Gamma-soluble NSF attachment protein" [UniProtKB:Q99747] synonym: "N-ethylmaleimide-sensitive factor attachment protein gamma" EXACT [UniProtKB:Q99747] synonym: "SNAP-gamma" EXACT [UniProtKB:Q99747] xref: EMBL:AAB69753.1 xref: EMBL:AAH01889.1 xref: UniProtKB:Q99747 xref: UniProtKB:Q9BUV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019959 ! NAPG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002964 ! protein stabilization relationship: transforms_into CCO:B0070676 ! SNAG_HUMAN-Phosphoserine284 relationship: transforms_into CCO:B0070677 ! SNAG_HUMAN-Phosphotyrosine307 [Term] id: CCO:B0058453 name: NRTN_HUMAN def: "Neurturin precursor" [UniProtKB:Q99748] xref: EMBL:AAC50898.1 xref: EMBL:CAB82327.1 xref: UniProtKB:Q99748 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018871 ! NRTN_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0058454 name: CML1_HUMAN def: "Chemokine receptor-like 1" [UniProtKB:Q99788] synonym: "G-protein coupled receptor ChemR23" EXACT [UniProtKB:Q99788] synonym: "G-protein coupled receptor DEZ" EXACT [UniProtKB:Q99788] xref: EMBL:AAC51258.1 xref: EMBL:AAC51259.1 xref: EMBL:AAI06928.1 xref: EMBL:AAI06929.1 xref: EMBL:AAR90850.1 xref: EMBL:BAC06089.1 xref: EMBL:CAA75112.1 xref: UniProtKB:O75748 xref: UniProtKB:Q3KP37 xref: UniProtKB:Q99788 xref: UniProtKB:Q99789 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017394 ! CMKLR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001286 ! C5a anaphylatoxin receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058455 name: NKX31_HUMAN def: "Homeobox protein Nkx-3.1" [UniProtKB:Q99801] synonym: "Homeobox protein NK-3 homolog A" EXACT [UniProtKB:Q99801] xref: EMBL:AAB38747.1 xref: EMBL:AAB68662.1 xref: EMBL:AAG09781.1 xref: EMBL:AAG39735.1 xref: EMBL:AAG39736.1 xref: EMBL:AAG39737.1 xref: EMBL:AAG39738.1 xref: EMBL:AAH74863.1 xref: EMBL:AAH74864.1 xref: UniProtKB:O15465 xref: UniProtKB:Q99801 xref: UniProtKB:Q9H2P4 xref: UniProtKB:Q9H2P5 xref: UniProtKB:Q9H2P6 xref: UniProtKB:Q9H2P7 xref: UniProtKB:Q9HBG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018800 ! NKX3-1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058456 name: PRRX2_HUMAN def: "Paired mesoderm homeobox protein 2" [UniProtKB:Q99811] synonym: "Paired-related homeobox protein 2" EXACT [UniProtKB:Q99811] synonym: "PRX-2" EXACT [UniProtKB:Q99811] xref: EMBL:AAB39864.1 xref: EMBL:AAF17708.1 xref: EMBL:AAH14645.1 xref: UniProtKB:Q99811 xref: UniProtKB:Q9UIB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019522 ! PRRX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058457 name: GDIR3_HUMAN def: "Rho GDP-dissociation inhibitor 3" [UniProtKB:Q99819] synonym: "Rho GDI 3" EXACT [UniProtKB:Q99819] synonym: "Rho-GDI gamma" EXACT [UniProtKB:Q99819] xref: EMBL:AAC33138.1 xref: EMBL:AAC72354.1 xref: EMBL:AAH47699.1 xref: EMBL:AAK61222.1 xref: EMBL:AAM21076.1 xref: EMBL:BAE48733.1 xref: EMBL:CAI95584.1 xref: UniProtKB:Q4TT69 xref: UniProtKB:Q96S29 xref: UniProtKB:Q99819 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017911 ! ARHGDIG_human relationship: has_function CCO:F0001399 ! Rho GDP-dissociation inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000783 ! Rho protein signal transduction [Term] id: CCO:B0058458 name: MYD88_HUMAN def: "Myeloid differentiation primary response protein MyD88" [UniProtKB:Q99836] xref: EMBL:AAB49967.1 xref: EMBL:AAC50954.1 xref: EMBL:AAH13589.1 xref: UniProtKB:P78397 xref: UniProtKB:Q99836 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018695 ! MYD88_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001423 ! Toll binding relationship: has_function CCO:F0001425 ! death receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0015763 ! myd88-spop physical interaction relationship: participates_in CCO:I0015992 ! st2-myd88-1 physical interaction relationship: participates_in CCO:I0016113 ! fadd-myd88 physical interaction relationship: participates_in CCO:I0016114 ! fadd-myd88-1 physical interaction relationship: participates_in CCO:I0016267 ! myd88-tirap-1 physical interaction relationship: participates_in CCO:I0017933 ! tlr2-myd88 colocalization relationship: participates_in CCO:I0017989 ! irak3-myd88-ex1 physical interaction relationship: participates_in CCO:I0017990 ! irak1-myd88-ex1 physical interaction relationship: participates_in CCO:I0017991 ! irak2-myd88-ex1 physical interaction relationship: participates_in CCO:I0019233 ! irak4-peli2-1 physical interaction relationship: participates_in CCO:I0019363 ! tirap-myd88 physical interaction relationship: participates_in CCO:I0019364 ! myd88-tirap physical interaction relationship: participates_in CCO:I0019365 ! myd88 physical interaction relationship: participates_in CCO:P0000571 ! MyD88-dependent toll-like receptor signaling pathway relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000810 ! Toll signaling pathway relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0001484 ! lipopolysaccharide-mediated signaling pathway relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002272 ! positive regulation of chemokine biosynthetic process relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0058459 name: ARI3A_HUMAN def: "AT-rich interactive domain-containing protein 3A" [UniProtKB:Q99856] synonym: "ARID domain-containing protein 3A" EXACT [UniProtKB:Q99856] synonym: "B-cell regulator of IgH transcription" EXACT [UniProtKB:Q99856] synonym: "Bright" EXACT [UniProtKB:Q99856] synonym: "Dead ringer-like protein 1" EXACT [UniProtKB:Q99856] synonym: "E2F-binding protein 1" EXACT [UniProtKB:Q99856] xref: EMBL:AAC28499.1 xref: EMBL:AAC28918.1 xref: EMBL:AAC32888.1 xref: EMBL:AAC69994.1 xref: EMBL:AAH33163.1 xref: EMBL:AAH60828.1 xref: EMBL:AAN74028.1 xref: EMBL:AAW30734.1 xref: UniProtKB:Q5I858 xref: UniProtKB:Q6P9C6 xref: UniProtKB:Q8IZA7 xref: UniProtKB:Q8N4Z3 xref: UniProtKB:Q99856 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017028 ! ARID3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063574 ! ARI3A_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0063575 ! ARI3A_HUMAN-Phosphoserine81 relationship: transforms_into CCO:B0063576 ! ARI3A_HUMAN-Phosphoserine88 [Term] id: CCO:B0058460 name: SSX3_HUMAN def: "Protein SSX3" [UniProtKB:Q99909] synonym: "Cancer/testis antigen 5.3" EXACT [UniProtKB:Q99909] synonym: "CT5.3" EXACT [UniProtKB:Q99909] xref: EMBL:AAB37436.2 xref: EMBL:AAC05819.1 xref: EMBL:AAI03863.1 xref: EMBL:CAI40268.1 xref: UniProtKB:O60223 xref: UniProtKB:Q5JQZ3 xref: UniProtKB:Q99909 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020050 ! SSX3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058461 name: ASCL2_HUMAN def: "Achaete-scute homolog 2" [UniProtKB:Q99929] synonym: "HASH2" EXACT [UniProtKB:Q99929] synonym: "Mash2" EXACT [UniProtKB:Q99929] xref: EMBL:AAB39362.1 xref: EMBL:AAB86993.1 xref: EMBL:AAL35362.1 xref: UniProtKB:Q99929 xref: UniProtKB:Q9UM68 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017076 ! ASCL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058462 name: BAG1_HUMAN def: "BAG family molecular chaperone regulator 1" [UniProtKB:Q99933] synonym: "BAG-1" EXACT [UniProtKB:Q99933] synonym: "Bcl-2-associated athanogene 1" EXACT [UniProtKB:Q99933] synonym: "Glucocorticoid receptor-associated protein RAP46" EXACT [UniProtKB:Q99933] xref: EMBL:AAC34258.1 xref: EMBL:AAD11467.1 xref: EMBL:AAD25045.1 xref: EMBL:AAH01936.2 xref: EMBL:AAH14774.2 xref: EMBL:CAA84624.1 xref: UniProtKB:O75315 xref: UniProtKB:Q14414 xref: UniProtKB:Q96TG2 xref: UniProtKB:Q99933 xref: UniProtKB:Q9Y2V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017116 ! BAG1_human relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0058463 name: ATF6B_HUMAN def: "Cyclic AMP-dependent transcription factor ATF-6 beta" [UniProtKB:Q99941] synonym: "Activating transcription factor 6 beta" EXACT [UniProtKB:Q99941] synonym: "ATF6-beta" EXACT [UniProtKB:Q99941] synonym: "cAMP response element-binding protein-related protein" EXACT [UniProtKB:Q99941] synonym: "cAMP-responsive element-binding protein-like 1" EXACT [UniProtKB:Q99941] synonym: "Creb-rp" EXACT [UniProtKB:Q99941] synonym: "Protein G13" EXACT [UniProtKB:Q99941] xref: EMBL:AAA97438.1 xref: EMBL:AAB47487.1 xref: EMBL:AAC50883.1 xref: EMBL:AAC50888.1 xref: EMBL:AAG14898.1 xref: EMBL:AAG14900.1 xref: EMBL:CAA66663.1 xref: EMBL:CAA66664.1 xref: EMBL:CAB89295.1 xref: EMBL:CAI17416.1 xref: EMBL:CAI17419.1 xref: EMBL:CAI18334.1 xref: EMBL:CAI18336.2 xref: EMBL:CAQ09553.1 xref: EMBL:CAQ10264.1 xref: EMBL:EAX03581.1 xref: UniProtKB:Q13269 xref: UniProtKB:Q14343 xref: UniProtKB:Q14345 xref: UniProtKB:Q5SSW7 xref: UniProtKB:Q99635 xref: UniProtKB:Q99637 xref: UniProtKB:Q99941 xref: UniProtKB:Q9H3V9 xref: UniProtKB:Q9H3W1 xref: UniProtKB:Q9NPL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017095 ! CREBL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058464 name: DUS9_HUMAN def: "Dual specificity protein phosphatase 9" [UniProtKB:Q99956] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q99956] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q99956] synonym: "MAP kinase phosphatase 4" EXACT [UniProtKB:Q99956] synonym: "Mitogen-activated protein kinase phosphatase 4" EXACT [UniProtKB:Q99956] synonym: "MKP-4" EXACT [UniProtKB:Q99956] xref: EMBL:CAA69610.1 xref: UniProtKB:Q99956 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017636 ! DUSP9_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000772 ! JNK cascade [Term] id: CCO:B0058465 name: SEM3C_HUMAN def: "Semaphorin-3C precursor" [UniProtKB:Q99985] synonym: "Sema E" EXACT [UniProtKB:Q99985] synonym: "Semaphorin-E" EXACT [UniProtKB:Q99985] xref: EMBL:AAH30690.1 xref: EMBL:BAA32398.1 xref: UniProtKB:Q99985 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019866 ! SEMA3C_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:B0058466 name: GDF15_HUMAN def: "Growth/differentiation factor 15 precursor" [UniProtKB:Q99988] synonym: "GDF-15" EXACT [UniProtKB:Q99988] synonym: "Macrophage inhibitory cytokine 1" EXACT [UniProtKB:Q99988] synonym: "MIC-1" EXACT [UniProtKB:Q99988] synonym: "NAG-1" EXACT [UniProtKB:Q99988] synonym: "NRG-1" EXACT [UniProtKB:Q99988] synonym: "NSAID-activated gene 1 protein" EXACT [UniProtKB:Q99988] synonym: "NSAID-regulated gene 1 protein" EXACT [UniProtKB:Q99988] synonym: "Placental bone morphogenetic protein" EXACT [UniProtKB:Q99988] synonym: "Placental TGF-beta" EXACT [UniProtKB:Q99988] synonym: "Prostate differentiation factor" EXACT [UniProtKB:Q99988] xref: EMBL:AAB88673.1 xref: EMBL:AAB88913.1 xref: EMBL:AAC24456.1 xref: EMBL:AAC39537.1 xref: EMBL:AAF89834.1 xref: EMBL:AAH00529.1 xref: EMBL:AAH08962.1 xref: EMBL:AAV38272.1 xref: EMBL:BAA19151.1 xref: EMBL:BAF84219.1 xref: EMBL:EAW84694.1 xref: UniProtKB:O14629 xref: UniProtKB:P78360 xref: UniProtKB:Q99988 xref: UniProtKB:Q9BWA0 xref: UniProtKB:Q9NRT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017904 ! GDF15_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:B0058467 name: VGLL1_HUMAN def: "Transcription cofactor vestigial-like protein 1" [UniProtKB:Q99990] synonym: "Protein TONDU" EXACT [UniProtKB:Q99990] synonym: "Vgl-1" EXACT [UniProtKB:Q99990] xref: EMBL:AAB46354.1 xref: EMBL:AAF13149.1 xref: EMBL:AAH00045.1 xref: EMBL:AAH03362.1 xref: UniProtKB:Q99990 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020445 ! VGLL1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058468 name: DPYL5_HUMAN def: "Dihydropyrimidinase-related protein 5" [UniProtKB:Q9BPU6] synonym: "Collapsin response mediator protein 5" EXACT [UniProtKB:Q9BPU6] synonym: "CRAM" EXACT [UniProtKB:Q9BPU6] synonym: "CRMP-5" EXACT [UniProtKB:Q9BPU6] synonym: "CRMP3-associated molecule" EXACT [UniProtKB:Q9BPU6] synonym: "DRP-5" EXACT [UniProtKB:Q9BPU6] synonym: "ULIP6 protein" EXACT [UniProtKB:Q9BPU6] xref: EMBL:AAF80348.1 xref: EMBL:AAH02874.1 xref: EMBL:AAK16830.1 xref: EMBL:AAP35517.1 xref: EMBL:CAB95124.1 xref: EMBL:CAD28503.1 xref: UniProtKB:Q8TCL6 xref: UniProtKB:Q9BPU6 xref: UniProtKB:Q9NQC4 xref: UniProtKB:Q9NRY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017616 ! DPYSL5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001709 ! cell soma relationship: participates_in CCO:I0020545 ! dpysl5-hspa5 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064875 ! DPYL5_HUMAN-Phosphothreonine509 relationship: transforms_into CCO:B0064876 ! DPYL5_HUMAN-Phosphothreonine514 relationship: transforms_into CCO:B0064877 ! DPYL5_HUMAN-Phosphothreonine516 relationship: transforms_into CCO:B0064878 ! DPYL5_HUMAN-Phosphoserine534 [Term] id: CCO:B0058469 name: P2Y13_HUMAN def: "P2Y purinoceptor 13" [UniProtKB:Q9BPV8] synonym: "G-protein coupled receptor 86" EXACT [UniProtKB:Q9BPV8] synonym: "G-protein coupled receptor 94" EXACT [UniProtKB:Q9BPV8] synonym: "P2Y13" EXACT [UniProtKB:Q9BPV8] xref: EMBL:AAH41116.2 xref: EMBL:AAK01864.1 xref: EMBL:AAK29068.1 xref: EMBL:AAL01038.1 xref: EMBL:AAL26484.1 xref: EMBL:BAB89310.1 xref: UniProtKB:Q8IUT5 xref: UniProtKB:Q8TDU7 xref: UniProtKB:Q9BPV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019273 ! P2RY13_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058470 name: RSLBB_HUMAN def: "Ras-like protein family member 11B" [UniProtKB:Q9BPW5] xref: EMBL:AAH01087.1 xref: EMBL:AAH01846.1 xref: EMBL:AAH25694.1 xref: EMBL:AAX46798.1 xref: EMBL:BAB55008.1 xref: EMBL:DAA02135.1 xref: EMBL:EAX05441.1 xref: UniProtKB:Q96KC5 xref: UniProtKB:Q9BPW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019802 ! RASL11B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015177 ! ewsr1-rasl11b physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058471 name: ARP5L_HUMAN def: "Actin-related protein 2/3 complex subunit 5-like protein" [UniProtKB:Q9BPX5] synonym: "ARC16-2" EXACT [UniProtKB:Q9BPX5] synonym: "Arp2/3 complex 16 kDa subunit 2" EXACT [UniProtKB:Q9BPX5] xref: EMBL:AAH00018.1 xref: EMBL:AAH00798.1 xref: EMBL:AAH02418.1 xref: EMBL:AAP97155.1 xref: EMBL:CAI39641.1 xref: UniProtKB:Q7Z523 xref: UniProtKB:Q9BPX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017047 ! ARPC5L_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0019526 ! arpc5l-arpc4 physical interaction relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: transforms_into CCO:B0063612 ! ARP5L_HUMAN-Phosphoserine64 [Term] id: CCO:B0058472 name: HOP_HUMAN def: "Homeodomain-only protein" [UniProtKB:Q9BPY8] synonym: "Lung cancer-associated Y protein" EXACT [UniProtKB:Q9BPY8] synonym: "Not expressed in choriocarcinoma protein 1" EXACT [UniProtKB:Q9BPY8] synonym: "Odd homeobox protein 1" EXACT [UniProtKB:Q9BPY8] xref: EMBL:AAH14225.1 xref: EMBL:AAL56613.1 xref: EMBL:AAM46827.1 xref: EMBL:AAM46828.1 xref: EMBL:AAM46829.1 xref: EMBL:AAM46830.1 xref: EMBL:AAM46831.1 xref: EMBL:AAM46832.1 xref: EMBL:AAM46833.1 xref: EMBL:BAB40926.1 xref: EMBL:BAB40927.1 xref: EMBL:BAB40928.1 xref: UniProtKB:Q8N0V6 xref: UniProtKB:Q96CI1 xref: UniProtKB:Q9BPY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018156 ! HOPX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:B0058473 name: PAIP2_HUMAN def: "Polyadenylate-binding protein-interacting protein 2" [UniProtKB:Q9BPZ3] synonym: "PABP-interacting protein 2" EXACT [UniProtKB:Q9BPZ3] synonym: "PAIP-2" EXACT [UniProtKB:Q9BPZ3] synonym: "Poly(A)-binding protein-interacting protein 2" EXACT [UniProtKB:Q9BPZ3] xref: EMBL:AAF36138.1 xref: EMBL:AAH01716.1 xref: EMBL:AAH48106.1 xref: EMBL:AAH62718.1 xref: EMBL:AAK11562.1 xref: EMBL:CAB66575.1 xref: UniProtKB:Q49A06 xref: UniProtKB:Q9BPZ3 xref: UniProtKB:Q9H0Y5 xref: UniProtKB:Q9P0Q8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019293 ! PAIP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004416 ! translation repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0002630 ! negative regulation of translational initiation [Term] id: CCO:B0058474 name: RETNB_HUMAN def: "Resistin-like beta precursor" [UniProtKB:Q9BQ08] synonym: "Colon and small intestine-specific cysteine-rich protein" EXACT [UniProtKB:Q9BQ08] synonym: "Colon carcinoma-related gene protein" EXACT [UniProtKB:Q9BQ08] synonym: "Cysteine-rich secreted protein A12-alpha-like 1" EXACT [UniProtKB:Q9BQ08] synonym: "Cysteine-rich secreted protein FIZZ2" EXACT [UniProtKB:Q9BQ08] synonym: "RELMbeta" EXACT [UniProtKB:Q9BQ08] xref: EMBL:AAG59827.1 xref: EMBL:AAH69318.1 xref: EMBL:AAI13503.1 xref: EMBL:AAI13529.1 xref: EMBL:AAK18622.1 xref: EMBL:AAK83105.1 xref: EMBL:AAL96378.1 xref: EMBL:AAQ89018.1 xref: UniProtKB:Q14D27 xref: UniProtKB:Q9BQ08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019678 ! RETNLB_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0058475 name: TCF25_HUMAN def: "Transcription factor 25" [UniProtKB:Q9BQ70] synonym: "Nuclear localized protein 1" EXACT [UniProtKB:Q9BQ70] xref: EMBL:AAG50276.1 xref: EMBL:AAH00959.1 xref: EMBL:AAH09349.1 xref: EMBL:AAH11884.1 xref: EMBL:ABC55265.1 xref: EMBL:BAA83001.1 xref: UniProtKB:Q2MK75 xref: UniProtKB:Q9BQ70 xref: UniProtKB:Q9UPV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020216 ! TCF25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015167 ! fksg26-sat physical interaction relationship: participates_in CCO:I0015489 ! fksg26-magea11 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071284 ! TCF25_HUMAN-Phosphoserine602 [Term] id: CCO:B0058476 name: Q9BQ85_HUMAN def: "Zinc finger protein 655" [UniProtKB:Q9BQ85] synonym: "Putative uncharacterized protein VIK" EXACT [UniProtKB:Q9BQ85] synonym: "Vav-1 interacting Kruppel-like protein" EXACT [UniProtKB:Q9BQ85] synonym: "Zinc finger protein 655, isoform CRA_b" EXACT [UniProtKB:Q9BQ85] xref: EMBL:AAH00823.1 xref: EMBL:AAH04288.1 xref: EMBL:AAH07378.1 xref: EMBL:AAS02017.1 xref: EMBL:EAL23871.1 xref: EMBL:EAW76650.1 xref: UniProtKB:Q9BQ85 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0005966 ! ZNF655_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015004 ! c12orf11-znf655 physical interaction relationship: participates_in CCO:I0015329 ! trim37-znf655 physical interaction relationship: participates_in CCO:I0015647 ! krtap4_12-znf655 physical interaction relationship: participates_in CCO:I0015790 ! magea11-znf655 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058477 name: TBL1Y_HUMAN def: "F-box-like/WD repeat-containing protein TBL1Y" [UniProtKB:Q9BQ87] synonym: "Transducin beta-like 1Y protein" EXACT [UniProtKB:Q9BQ87] synonym: "Transducin-beta-like 1, Y-linked" EXACT [UniProtKB:Q9BQ87] xref: EMBL:AAK13472.1 xref: EMBL:AAK13473.1 xref: EMBL:AAK13474.1 xref: UniProtKB:Q9BQ87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020189 ! TBL1Y_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058478 name: MIZF_HUMAN def: "MBD2-interacting zinc finger protein" [UniProtKB:Q9BQA5] synonym: "HiNF-P" EXACT [UniProtKB:Q9BQA5] synonym: "Histone nuclear factor P" EXACT [UniProtKB:Q9BQA5] synonym: "Methyl-CpG-binding protein 2-interacting zinc finger protein" EXACT [UniProtKB:Q9BQA5] xref: EMBL:AAH01073.1 xref: EMBL:AAH01945.1 xref: EMBL:AAH12856.1 xref: EMBL:AAH17234.1 xref: EMBL:CAB45773.1 xref: UniProtKB:Q96E65 xref: UniProtKB:Q9BQA5 xref: UniProtKB:Q9Y4M7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018629 ! MIZF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015462 ! mizf-traf2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058479 name: SOST_HUMAN def: "Sclerostin precursor" [UniProtKB:Q9BQB4] xref: EMBL:AAI01087.1 xref: EMBL:AAI01088.1 xref: EMBL:AAI01089.1 xref: EMBL:AAI01090.1 xref: EMBL:AAK13451.1 xref: EMBL:AAK13454.1 xref: EMBL:AAK16158.1 xref: EMBL:AAQ88570.1 xref: EMBL:AAQ88990.1 xref: UniProtKB:Q495N9 xref: UniProtKB:Q9BQB4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019988 ! SOST_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway [Term] id: CCO:B0058480 name: SELS_HUMAN def: "Selenoprotein S" [UniProtKB:Q9BQE4] synonym: "SelS" EXACT [UniProtKB:Q9BQE4] synonym: "VCP-interacting membrane protein" EXACT [UniProtKB:Q9BQE4] xref: EMBL:AAF67483.1 xref: EMBL:AAH05840.2 xref: EMBL:AAI07775.1 xref: EMBL:AAK15708.1 xref: EMBL:AAP85541.1 xref: UniProtKB:Q3B771 xref: UniProtKB:Q9BQE4 xref: UniProtKB:Q9P0I6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019864 ! SELS_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001897 ! selenium binding relationship: has_function CCO:F0003069 ! antioxidant activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: located_in CCO:C0002141 ! very-low-density lipoprotein particle relationship: located_in CCO:C0002142 ! low-density lipoprotein particle relationship: participates_in CCO:I0017670 ! vcp-der1-sels-1 physical interaction relationship: participates_in CCO:I0017848 ! vcp-der1-sels-2 colocalization relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000684 ! ER overload response relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: transforms_into CCO:B0070369 ! SELS_HUMAN-Phosphoserine140 [Term] id: CCO:B0058481 name: MBB1A_HUMAN def: "Myb-binding protein 1A" [UniProtKB:Q9BQG0] xref: EMBL:AAF33021.1 xref: EMBL:AAH00641.2 xref: EMBL:AAH50546.1 xref: EMBL:CAB61409.1 xref: EMBL:CAB66530.1 xref: UniProtKB:Q86VM3 xref: UniProtKB:Q9BQG0 xref: UniProtKB:Q9BW49 xref: UniProtKB:Q9P0V5 xref: UniProtKB:Q9UF99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018577 ! MYBBP1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0068020 ! MBB1A_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0068021 ! MBB1A_HUMAN-Phosphotyrosine60 relationship: transforms_into CCO:B0068022 ! MBB1A_HUMAN-Phosphoserine775 relationship: transforms_into CCO:B0068023 ! MBB1A_HUMAN-Phosphoserine1159 relationship: transforms_into CCO:B0068024 ! MBB1A_HUMAN-Phosphoserine1163 relationship: transforms_into CCO:B0068025 ! MBB1A_HUMAN-Phosphoserine1166 relationship: transforms_into CCO:B0068026 ! MBB1A_HUMAN-Phosphoserine1186 relationship: transforms_into CCO:B0068027 ! MBB1A_HUMAN-Phosphothreonine1190 relationship: transforms_into CCO:B0068028 ! MBB1A_HUMAN-Phosphothreonine1196 relationship: transforms_into CCO:B0068029 ! MBB1A_HUMAN-Phosphoserine1207 relationship: transforms_into CCO:B0068030 ! MBB1A_HUMAN-Phosphoserine1241 relationship: transforms_into CCO:B0068031 ! MBB1A_HUMAN-Phosphothreonine1244 relationship: transforms_into CCO:B0068032 ! MBB1A_HUMAN-Phosphoserine1248 relationship: transforms_into CCO:B0068033 ! MBB1A_HUMAN-Phosphoserine1267 relationship: transforms_into CCO:B0068034 ! MBB1A_HUMAN-Phosphoserine1290 relationship: transforms_into CCO:B0068035 ! MBB1A_HUMAN-Phosphoserine1293 relationship: transforms_into CCO:B0068036 ! MBB1A_HUMAN-Phosphoserine1303 relationship: transforms_into CCO:B0068037 ! MBB1A_HUMAN-Phosphoserine1308 relationship: transforms_into CCO:B0068038 ! MBB1A_HUMAN-Phosphoserine1314 [Term] id: CCO:B0058482 name: PSD2_HUMAN def: "PH and SEC7 domain-containing protein 2" [UniProtKB:Q9BQI7] synonym: "Pleckstrin homology and SEC7 domain-containing protein 2" EXACT [UniProtKB:Q9BQI7] xref: EMBL:AAH38233.1 xref: EMBL:CAB66494.1 xref: EMBL:CAD38943.1 xref: EMBL:EAW62088.1 xref: UniProtKB:Q8N3J8 xref: UniProtKB:Q9BQI7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019525 ! PSD2_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:B0058483 name: COE4_HUMAN def: "Transcription factor COE4" [UniProtKB:Q9BQW3] synonym: "Early B-cell factor 4" EXACT [UniProtKB:Q9BQW3] synonym: "EBF-4" EXACT [UniProtKB:Q9BQW3] synonym: "O/E-4" EXACT [UniProtKB:Q9BQW3] synonym: "OE-4" EXACT [UniProtKB:Q9BQW3] synonym: "Olf-1/EBF-like 4" EXACT [UniProtKB:Q9BQW3] xref: EMBL:BAA92680.1 xref: EMBL:CAB82244.1 xref: UniProtKB:Q1MTP7 xref: UniProtKB:Q5JY53 xref: UniProtKB:Q9BQW3 xref: UniProtKB:Q9NUB6 xref: UniProtKB:Q9P2A6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017429 ! EBF4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058484 name: NEUL2_HUMAN def: "Neuralized-like protein 2" [UniProtKB:Q9BR09] xref: EMBL:AAH74737.1 xref: EMBL:AAI05936.1 xref: EMBL:AAI07486.1 xref: EMBL:BAB70810.1 xref: EMBL:CAC36018.1 xref: EMBL:CAC82498.1 xref: UniProtKB:Q3KR34 xref: UniProtKB:Q9BR09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018758 ! NEURL2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000479 ! muscle tendon junction relationship: located_in CCO:C0001069 ! VCB complex relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058485 name: ZN559_HUMAN def: "Zinc finger protein 559" [UniProtKB:Q9BR84] xref: EMBL:AAH06436.1 xref: UniProtKB:Q9BR84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020818 ! ZNF559_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015262 ! mdfi-znf559 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058486 name: Q9BR93_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q9BR93] xref: EMBL:AAH06419.1 xref: UniProtKB:Q9BR93 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058487 name: Q9BR99_HUMAN def: "Zinc finger protein 493" [UniProtKB:Q9BR99] xref: EMBL:AAH06408.1 xref: UniProtKB:Q9BR99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020777 ! ZNF493_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058488 name: TXD17_HUMAN def: "Thioredoxin domain-containing protein 17" [UniProtKB:Q9BRA2] synonym: "14 kDa thioredoxin-related protein" EXACT [UniProtKB:Q9BRA2] synonym: "Protein 42-9-9" EXACT [UniProtKB:Q9BRA2] synonym: "Thioredoxin-like protein 5" EXACT [UniProtKB:Q9BRA2] synonym: "TRP14" EXACT [UniProtKB:Q9BRA2] xref: EMBL:AAH06405.1 xref: EMBL:CAC51435.1 xref: UniProtKB:Q9BRA2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020388 ! TXNDC17_human relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0006446 ! protein-disulfide reductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:P0001810 ! tumor necrosis factor-mediated signaling pathway [Term] id: CCO:B0058489 name: PLCD4_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4" [UniProtKB:Q9BRC7] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q9BRC7] synonym: "hPLCD4" EXACT [UniProtKB:Q9BRC7] synonym: "Phosphoinositide phospholipase C delta-4" EXACT [UniProtKB:Q9BRC7] synonym: "Phospholipase C-delta-4" EXACT [UniProtKB:Q9BRC7] synonym: "PLC-delta-4" EXACT [UniProtKB:Q9BRC7] xref: EMBL:AAH06355.1 xref: EMBL:AAS82574.1 xref: EMBL:BAD96923.1 xref: UniProtKB:Q53FS8 xref: UniProtKB:Q9BRC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019432 ! PLCD4_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015445 ! plcd4-trim39 physical interaction relationship: participates_in CCO:I0015621 ! ipo11-plcd4 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058490 name: VPS25_HUMAN def: "Vacuolar protein-sorting-associated protein 25" [UniProtKB:Q9BRG1] synonym: "Dermal papilla-derived protein 9" EXACT [UniProtKB:Q9BRG1] synonym: "ELL-associated protein of 20 kDa" EXACT [UniProtKB:Q9BRG1] synonym: "hVps25" EXACT [UniProtKB:Q9BRG1] xref: EMBL:AAH06282.1 xref: EMBL:BAB87804.1 xref: UniProtKB:Q9BRG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020462 ! VPS25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015025 ! pepp2-vps25 physical interaction relationship: participates_in CCO:I0015357 ! snf8-vps25 physical interaction relationship: participates_in CCO:I0015431 ! mmrp19-vps25 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058491 name: SH23A_HUMAN def: "SH2 domain-containing protein 3A" [UniProtKB:Q9BRG2] synonym: "Novel SH2-containing protein 1" EXACT [UniProtKB:Q9BRG2] xref: EMBL:AAD28244.1 xref: EMBL:AAH06281.1 xref: EMBL:AAQ88772.1 xref: UniProtKB:Q9BRG2 xref: UniProtKB:Q9Y2X4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019885 ! SH2D3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000772 ! JNK cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0070460 ! SH23A_HUMAN-Phosphoserine123 relationship: transforms_into CCO:B0070461 ! SH23A_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0070462 ! SH23A_HUMAN-Phosphoserine180 [Term] id: CCO:B0058492 name: ZN251_HUMAN def: "Zinc finger protein 251" [UniProtKB:Q9BRH9] xref: EMBL:AAH06258.2 xref: EMBL:AAI12138.1 xref: UniProtKB:Q2M219 xref: UniProtKB:Q9BRH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020679 ! ZNF251_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058493 name: MESP1_HUMAN def: "Mesoderm posterior protein 1" [UniProtKB:Q9BRJ9] xref: EMBL:AAH06219.1 xref: EMBL:CAB93425.1 xref: EMBL:CAB93426.1 xref: UniProtKB:Q9BRJ9 xref: UniProtKB:Q9NSF1 xref: UniProtKB:Q9NSF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018605 ! MESP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058494 name: AIFM2_HUMAN def: "Apoptosis-inducing factor 2" [UniProtKB:Q9BRQ8] synonym: "Apoptosis-inducing factor homologous mitochondrion-associated inducer of death" EXACT [UniProtKB:Q9BRQ8] synonym: "Apoptosis-inducing factor-like mitochondrion-associated inducer of death" EXACT [UniProtKB:Q9BRQ8] synonym: "EC 1.-.-.-" EXACT [UniProtKB:Q9BRQ8] synonym: "p53-responsive gene 3 protein" EXACT [UniProtKB:Q9BRQ8] xref: EMBL:AAH06121.1 xref: EMBL:AAH23601.1 xref: EMBL:AAL73229.1 xref: EMBL:AAM77596.1 xref: EMBL:BAB55089.1 xref: EMBL:CAH56481.1 xref: EMBL:CAI13684.1 xref: UniProtKB:Q63Z39 xref: UniProtKB:Q9BRQ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016936 ! AIFM2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000643 ! electron-transferring-flavoprotein dehydrogenase activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000844 ! apoptotic mitochondrial changes [Term] id: CCO:B0058495 name: ZKSC3_HUMAN def: "Zinc finger protein with KRAB and SCAN domains 3" [UniProtKB:Q9BRR0] synonym: "Zf47" EXACT [UniProtKB:Q9BRR0] synonym: "Zfp-47" EXACT [UniProtKB:Q9BRR0] synonym: "Zinc finger and SCAN domain-containing protein 13" EXACT [UniProtKB:Q9BRR0] synonym: "Zinc finger protein 306" EXACT [UniProtKB:Q9BRR0] synonym: "Zinc finger protein 309" EXACT [UniProtKB:Q9BRR0] synonym: "Zinc finger protein 47 homolog" EXACT [UniProtKB:Q9BRR0] xref: EMBL:AAB16813.1 xref: EMBL:AAH06118.1 xref: EMBL:AAP36095.1 xref: EMBL:CAH71668.1 xref: EMBL:CAI23088.1 xref: UniProtKB:Q5VXH3 xref: UniProtKB:Q92972 xref: UniProtKB:Q9BRR0 xref: UniProtKB:Q9H4T3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020610 ! ZKSCAN3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058496 name: RHG09_HUMAN def: "Rho GTPase-activating protein 9" [UniProtKB:Q9BRR9] synonym: "Rho-type GTPase-activating protein 9" EXACT [UniProtKB:Q9BRR9] xref: EMBL:AAH06107.1 xref: EMBL:AAH11820.1 xref: EMBL:BAB56159.1 xref: EMBL:BAB83128.1 xref: EMBL:CAD28552.1 xref: UniProtKB:Q8TCJ3 xref: UniProtKB:Q8WYR0 xref: UniProtKB:Q96EZ2 xref: UniProtKB:Q96S74 xref: UniProtKB:Q9BRR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019717 ! ARHGAP9_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: participates_in CCO:I0015576 ! arhgap9-rbpms physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058497 name: SLD5_HUMAN def: "DNA replication complex GINS protein SLD5" [UniProtKB:Q9BRT9] synonym: "GINS complex subunit 4" EXACT [UniProtKB:Q9BRT9] xref: EMBL:AAH05995.1 xref: EMBL:AAH27454.1 xref: EMBL:EAW63256.1 xref: UniProtKB:Q8N648 xref: UniProtKB:Q9BRT9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019932 ! GINS4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015342 ! psf2-sld5 physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058498 name: TCAL7_HUMAN def: "Transcription elongation factor A protein-like 7" [UniProtKB:Q9BRU2] synonym: "TCEA-like protein 7" EXACT [UniProtKB:Q9BRU2] synonym: "Transcription elongation factor S-II protein-like 7" EXACT [UniProtKB:Q9BRU2] xref: EMBL:AAH05988.2 xref: EMBL:AAH16786.1 xref: EMBL:CAI41965.1 xref: UniProtKB:Q96AT4 xref: UniProtKB:Q9BRU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020206 ! TCEAL7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058499 name: Q9BRW7_HUMAN def: "Synovial sarcoma, X breakpoint 3" [UniProtKB:Q9BRW7] synonym: "Synovial sarcoma, X breakpoint 3, isoform CRA_a" EXACT [UniProtKB:Q9BRW7] xref: EMBL:AAH05904.1 xref: EMBL:CAI40269.1 xref: EMBL:EAW59347.1 xref: UniProtKB:Q9BRW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020050 ! SSX3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058500 name: PSF3_HUMAN def: "DNA replication complex GINS protein PSF3" [UniProtKB:Q9BRX5] synonym: "GINS complex subunit 3" EXACT [UniProtKB:Q9BRX5] xref: EMBL:AAH05879.1 xref: EMBL:AAH14437.1 xref: EMBL:BAB14747.1 xref: EMBL:CAG33564.1 xref: EMBL:EAW82973.1 xref: EMBL:EAW82976.1 xref: UniProtKB:Q9BRX5 xref: UniProtKB:Q9H870 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019529 ! GINS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058501 name: Q9BRY4_HUMAN def: "SQSTM1 protein" [UniProtKB:Q9BRY4] xref: EMBL:AAH05857.3 xref: UniProtKB:Q9BRY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002161 ! regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058502 name: TXND4_HUMAN def: "Thioredoxin domain-containing protein 4 precursor" [UniProtKB:Q9BS26] synonym: "Endoplasmic reticulum resident protein ERp44" EXACT [UniProtKB:Q9BS26] xref: EMBL:AAH05374.1 xref: EMBL:AAQ89407.1 xref: EMBL:BAA25499.1 xref: EMBL:BAG52054.1 xref: EMBL:CAC87611.1 xref: EMBL:CAH70308.1 xref: EMBL:CAH72172.1 xref: EMBL:CAI95319.1 xref: UniProtKB:O60319 xref: UniProtKB:Q4VXC1 xref: UniProtKB:Q5VWZ7 xref: UniProtKB:Q6UW14 xref: UniProtKB:Q8WX67 xref: UniProtKB:Q9BS26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020391 ! TXNDC4_human relationship: has_function CCO:F0000320 ! protein disulfide isomerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: participates_in CCO:I0015935 ! itpr1-txndc4-2 physical interaction relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis [Term] id: CCO:B0058503 name: ZN649_HUMAN def: "Zinc finger protein 649" [UniProtKB:Q9BS31] xref: EMBL:AAH05368.1 xref: EMBL:BAB14191.1 xref: EMBL:BAG37871.1 xref: EMBL:CAD28482.1 xref: EMBL:EAW72050.1 xref: UniProtKB:A8MYJ5 xref: UniProtKB:B2RDC4 xref: UniProtKB:Q9BS31 xref: UniProtKB:Q9H9N2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020874 ! ZNF649_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058504 name: ZN670_HUMAN def: "Zinc finger protein 670" [UniProtKB:Q9BS34] xref: EMBL:AAH05360.1 xref: EMBL:BAC11200.1 xref: EMBL:CAH70012.1 xref: EMBL:CAI15616.1 xref: UniProtKB:Q9BS34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020886 ! ZNF670_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015173 ! kiaa1279-znf670 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072212 ! ZN670_HUMAN-Phosphotyrosine281 [Term] id: CCO:B0058505 name: ZNF2_HUMAN def: "Zinc finger protein 2" [UniProtKB:Q9BSG1] synonym: "Zinc finger protein 2.2" EXACT [UniProtKB:Q9BSG1] synonym: "Zinc finger protein 661" EXACT [UniProtKB:Q9BSG1] xref: EMBL:AAH05068.2 xref: EMBL:AAH09976.2 xref: EMBL:AAX88982.1 xref: EMBL:CAB52138.1 xref: UniProtKB:Q4ZFY6 xref: UniProtKB:Q96G44 xref: UniProtKB:Q9BSG1 xref: UniProtKB:Q9UMC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020968 ! ZNF2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058506 name: ZN577_HUMAN def: "Zinc finger protein 577" [UniProtKB:Q9BSK1] xref: EMBL:AAH04992.1 xref: UniProtKB:Q9BSK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020834 ! ZNF577_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058507 name: PCGF1_HUMAN def: "Polycomb group RING finger protein 1" [UniProtKB:Q9BSM1] synonym: "Nervous system Polycomb-1" EXACT [UniProtKB:Q9BSM1] synonym: "NSPc1" EXACT [UniProtKB:Q9BSM1] synonym: "RING finger protein 68" EXACT [UniProtKB:Q9BSM1] xref: EMBL:AAH04952.1 xref: EMBL:AAP97183.1 xref: UniProtKB:Q7Z506 xref: UniProtKB:Q9BSM1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019318 ! PCGF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015535 ! ndp52-pcgf1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058508 name: Q9BSN8_HUMAN def: "ZNF614 protein" [UniProtKB:Q9BSN8] synonym: "HCG2008146, isoform CRA_a" EXACT [UniProtKB:Q9BSN8] xref: EMBL:AAH04930.1 xref: EMBL:EAW72058.1 xref: UniProtKB:Q9BSN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020855 ! ZNF614_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058509 name: CCM2_HUMAN def: "Malcavernin" [UniProtKB:Q9BSQ5] synonym: "Cerebral cavernous malformations 2 protein" EXACT [UniProtKB:Q9BSQ5] xref: EMBL:AAH04903.1 xref: EMBL:AAH08859.1 xref: EMBL:AAH16832.1 xref: EMBL:AAH25958.1 xref: EMBL:AAQ15228.1 xref: UniProtKB:Q71RE5 xref: UniProtKB:Q8TAT4 xref: UniProtKB:Q9BSQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017275 ! CCM2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0003090 ! stress-activated MAPK cascade relationship: transforms_into CCO:B0064115 ! CCM2_HUMAN-Phosphoserine384 [Term] id: CCO:B0058510 name: RTKN_HUMAN def: "Rhotekin" [UniProtKB:Q9BST9] xref: EMBL:AAG01181.1 xref: EMBL:AAH04558.2 xref: EMBL:AAH17727.1 xref: EMBL:AAL16767.1 xref: UniProtKB:Q8WVN1 xref: UniProtKB:Q96PT6 xref: UniProtKB:Q9BST9 xref: UniProtKB:Q9HB05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019810 ! RTKN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0002544 ! regulation of anti-apoptosis relationship: transforms_into CCO:B0070254 ! RTKN_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0070255 ! RTKN_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0070256 ! RTKN_HUMAN-Phosphoserine543 [Term] id: CCO:B0058511 name: THAP7_HUMAN def: "THAP domain-containing protein 7" [UniProtKB:Q9BT49] xref: EMBL:AAH04346.1 xref: EMBL:CAG30229.1 xref: UniProtKB:Q9BT49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020251 ! THAP7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:I0015002 ! loc541468-thap7 physical interaction relationship: participates_in CCO:I0015088 ! set-thap7 physical interaction relationship: participates_in CCO:I0015289 ! thap7-traf2 physical interaction relationship: participates_in CCO:I0015319 ! mdfi-thap7 physical interaction relationship: participates_in CCO:I0015452 ! krtap4_12-thap7 physical interaction relationship: participates_in CCO:I0015604 ! ehmt2-thap7 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058512 name: NFIP1_HUMAN def: "NEDD4 family-interacting protein 1" [UniProtKB:Q9BT67] synonym: "Breast cancer-associated protein SGA-1M" EXACT [UniProtKB:Q9BT67] synonym: "NEDD4 WW domain-binding protein 5" EXACT [UniProtKB:Q9BT67] synonym: "Putative MAPK-activating protein PM13" EXACT [UniProtKB:Q9BT67] synonym: "Putative NF-kappa-B-activating protein 164" EXACT [UniProtKB:Q9BT67] synonym: "Putative NFKB and MAPK-activating protein" EXACT [UniProtKB:Q9BT67] xref: EMBL:AAH04317.1 xref: EMBL:AAP13460.1 xref: EMBL:BAC11652.1 xref: EMBL:BAC11670.1 xref: EMBL:BAC77363.1 xref: EMBL:BAC77390.1 xref: EMBL:CAH56294.1 xref: UniProtKB:Q658T8 xref: UniProtKB:Q8N2E3 xref: UniProtKB:Q8N2F9 xref: UniProtKB:Q9BT67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018776 ! NDFIP1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058513 name: SOX7_HUMAN def: "Transcription factor SOX-7" [UniProtKB:Q9BT81] xref: EMBL:AAH71947.1 xref: EMBL:BAB70955.1 xref: EMBL:CAC84226.1 xref: UniProtKB:Q9BT81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019993 ! SOX7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058514 name: MTA3_HUMAN def: "Metastasis-associated protein MTA3" [UniProtKB:Q9BTC8] xref: EMBL:AAH04227.1 xref: EMBL:AAH53631.1 xref: EMBL:BAA86580.1 xref: EMBL:BAB55028.1 xref: EMBL:CAB82305.1 xref: UniProtKB:Q9BTC8 xref: UniProtKB:Q9NSP2 xref: UniProtKB:Q9ULF4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018672 ! MTA3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058515 name: Q9BTN8_HUMAN def: "POLL protein" [UniProtKB:Q9BTN8] synonym: "Polymerase (DNA directed), lambda, isoform CRA_d" EXACT [UniProtKB:Q9BTN8] xref: EMBL:AAH03548.2 xref: EMBL:EAW49760.1 xref: UniProtKB:Q9BTN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017609 ! POLL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015021 ! ldoc1-poll physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058516 name: ZN692_HUMAN def: "Zinc finger protein 692" [UniProtKB:Q9BU19] xref: EMBL:AAG15327.1 xref: EMBL:AAH02948.1 xref: EMBL:BAA91239.1 xref: EMBL:BAA91490.1 xref: EMBL:CAB61410.2 xref: EMBL:CAI18799.1 xref: EMBL:CAI18800.1 xref: EMBL:CAI18801.1 xref: UniProtKB:Q5SRA5 xref: UniProtKB:Q5SRA6 xref: UniProtKB:Q9BU19 xref: UniProtKB:Q9HBC9 xref: UniProtKB:Q9NW93 xref: UniProtKB:Q9NWY6 xref: UniProtKB:Q9UF97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020901 ! ZNF692_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058517 name: CA089_HUMAN def: "Miro domain-containing protein C1orf89" [UniProtKB:Q9BU20] xref: EMBL:AAH02946.1 xref: EMBL:AAH08702.1 xref: EMBL:CAI22562.1 xref: UniProtKB:Q5TEV7 xref: UniProtKB:Q9BU20 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017201 ! C1orf89_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015583 ! c1orf89-flj22688 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058518 name: CRDL1_HUMAN def: "Chordin-like protein 1 precursor" [UniProtKB:Q9BU40] synonym: "Neuralin-1" EXACT [UniProtKB:Q9BU40] synonym: "Neurogenesin-1" EXACT [UniProtKB:Q9BU40] synonym: "Ventroptin" EXACT [UniProtKB:Q9BU40] xref: EMBL:AAH02909.2 xref: EMBL:CAI41336.1 xref: EMBL:CAI42037.1 xref: UniProtKB:Q9BU40 xref: UniProtKB:Q9Y3H7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017450 ! CHRDL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:B0058519 name: MKNK1_HUMAN def: "MAP kinase-interacting serine/threonine-protein kinase 1" [UniProtKB:Q9BUB5] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9BUB5] synonym: "MAP kinase signal-integrating kinase 1" EXACT [UniProtKB:Q9BUB5] synonym: "Mnk1" EXACT [UniProtKB:Q9BUB5] xref: EMBL:AAH02755.1 xref: EMBL:AAQ84219.1 xref: EMBL:BAA19885.1 xref: EMBL:CAI14765.1 xref: UniProtKB:O00312 xref: UniProtKB:Q5TC06 xref: UniProtKB:Q6V0N6 xref: UniProtKB:Q9BUB5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018633 ! MKNK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016131 ! eif4e-mnk1 physical interaction relationship: participates_in CCO:I0016132 ! mnk1-eif4e physical interaction relationship: participates_in CCO:I0016133 ! eif4g-mnk1 physical interaction relationship: participates_in CCO:I0016134 ! mnk1-eif4g physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0068219 ! MKNK1_HUMAN-Phosphothreonine250 relationship: transforms_into CCO:B0068220 ! MKNK1_HUMAN-Phosphothreonine255 relationship: transforms_into CCO:B0068221 ! MKNK1_HUMAN-Phosphothreonine385 relationship: transforms_into CCO:B0068222 ! MKNK1_HUMAN-Phosphoserine460 [Term] id: CCO:B0058520 name: ZSA5A_HUMAN def: "Zinc finger and SCAN domain-containing protein 5A" [UniProtKB:Q9BUG6] synonym: "Zinc finger protein 495" EXACT [UniProtKB:Q9BUG6] xref: EMBL:AAH02636.1 xref: EMBL:AAH43232.1 xref: EMBL:BAC05386.1 xref: EMBL:BAD97205.1 xref: UniProtKB:Q49A73 xref: UniProtKB:Q53F04 xref: UniProtKB:Q8N7B3 xref: UniProtKB:Q9BUG6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022829 ! ZSCAN5A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058521 name: RPC3_HUMAN def: "DNA-directed RNA polymerase III subunit RPC3" [UniProtKB:Q9BUI4] synonym: "DNA-directed III 62 kDa polypeptide" EXACT [UniProtKB:Q9BUI4] synonym: "DNA-directed RNA polymerase III subunit C" EXACT [UniProtKB:Q9BUI4] synonym: "RNA polymerase III subunit C3" EXACT [UniProtKB:Q9BUI4] synonym: "RPC62" EXACT [UniProtKB:Q9BUI4] xref: EMBL:AAB63675.1 xref: EMBL:AAH02586.1 xref: EMBL:AAM12033.1 xref: EMBL:CAB41919.1 xref: UniProtKB:O15317 xref: UniProtKB:Q9BUI4 xref: UniProtKB:Q9Y3R6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019782 ! POLR3C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter relationship: transforms_into CCO:B0070159 ! RPC3_HUMAN-Phosphoserine194 [Term] id: CCO:B0058522 name: HNRL1_HUMAN def: "Heterogeneous nuclear ribonucleoprotein U-like protein 1" [UniProtKB:Q9BUJ2] synonym: "Adenovirus early region 1B-associated protein 5" EXACT [UniProtKB:Q9BUJ2] synonym: "E1B-55 kDa-associated protein 5" EXACT [UniProtKB:Q9BUJ2] synonym: "E1B-AP5" EXACT [UniProtKB:Q9BUJ2] xref: EMBL:AAH02564.1 xref: EMBL:AAH09988.2 xref: EMBL:AAH14232.1 xref: EMBL:AAH27713.1 xref: EMBL:BAB13831.1 xref: EMBL:BAC86806.1 xref: EMBL:CAA07548.1 xref: EMBL:CAB43291.1 xref: UniProtKB:O76022 xref: UniProtKB:Q6ZSZ0 xref: UniProtKB:Q7L8P4 xref: UniProtKB:Q8N6Z4 xref: UniProtKB:Q96G37 xref: UniProtKB:Q9BUJ2 xref: UniProtKB:Q9HAL3 xref: UniProtKB:Q9UG75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018151 ! HNRNPUL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066859 ! HNRL1_HUMAN-Phosphoserine194 relationship: transforms_into CCO:B0066860 ! HNRL1_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0066861 ! HNRL1_HUMAN-Phosphoserine718 [Term] id: CCO:B0058523 name: DERL1_HUMAN def: "Derlin-1" [UniProtKB:Q9BUN8] synonym: "Degradation in endoplasmic reticulum protein 1" EXACT [UniProtKB:Q9BUN8] synonym: "Der1-like protein 1" EXACT [UniProtKB:Q9BUN8] synonym: "DERtrin-1" EXACT [UniProtKB:Q9BUN8] xref: EMBL:AAH02457.1 xref: EMBL:AAQ89177.1 xref: UniProtKB:Q9BUN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017558 ! DERL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017670 ! vcp-der1-sels-1 physical interaction relationship: participates_in CCO:I0017848 ! vcp-der1-sels-2 colocalization relationship: participates_in CCO:I0018560 ! rma1-cftr-2 physical interaction relationship: participates_in CCO:I0018561 ! rma1-cftr-3 physical interaction relationship: participates_in CCO:I0018562 ! rma1-cftr-4 physical interaction relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: transforms_into CCO:B0064741 ! DERL1_HUMAN-Phosphothreonine202 [Term] id: CCO:B0058524 name: ZN426_HUMAN def: "Zinc finger protein 426" [UniProtKB:Q9BUY5] xref: EMBL:AAH01791.1 xref: UniProtKB:Q9BUY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020745 ! ZNF426_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015055 ! mdfi-znf426 physical interaction relationship: participates_in CCO:I0015108 ! lpxn-znf426 physical interaction relationship: participates_in CCO:I0015308 ! krtap4_12-znf426 physical interaction relationship: participates_in CCO:I0015518 ! cep70-znf426 physical interaction relationship: participates_in CCO:I0015586 ! ndp52-znf426 physical interaction relationship: participates_in CCO:I0015626 ! efemp2-znf426 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058525 name: TRAF4_HUMAN def: "TNF receptor-associated factor 4" [UniProtKB:Q9BUZ4] synonym: "Cysteine-rich domain associated with RING and Traf domains protein 1" EXACT [UniProtKB:Q9BUZ4] synonym: "Malignant 62" EXACT [UniProtKB:Q9BUZ4] synonym: "RING finger protein 83" EXACT [UniProtKB:Q9BUZ4] xref: EMBL:AAC32376.1 xref: EMBL:AAH01769.1 xref: EMBL:ABC40750.1 xref: EMBL:CAA56491.1 xref: UniProtKB:O75615 xref: UniProtKB:Q14848 xref: UniProtKB:Q2PJN8 xref: UniProtKB:Q9BUZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020341 ! TRAF4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0071526 ! TRAF4_HUMAN-Phosphoserine426 [Term] id: CCO:B0058526 name: ZN747_HUMAN def: "KRAB domain-containing protein ZNF747" [UniProtKB:Q9BV97] xref: EMBL:AAH01361.1 xref: EMBL:BAB70760.1 xref: EMBL:BAD92783.1 xref: UniProtKB:Q59FB4 xref: UniProtKB:Q96NW0 xref: UniProtKB:Q9BV97 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020923 ! ZNF747_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058527 name: PHF20_HUMAN def: "PHD finger protein 20" [UniProtKB:Q9BVI0] synonym: "Glioma-expressed antigen 2" EXACT [UniProtKB:Q9BVI0] synonym: "Hepatocellular carcinoma-associated antigen 58" EXACT [UniProtKB:Q9BVI0] synonym: "Novel zinc finger protein" EXACT [UniProtKB:Q9BVI0] synonym: "Transcription factor TZP" EXACT [UniProtKB:Q9BVI0] xref: EMBL:AAF34184.1 xref: EMBL:AAG49888.1 xref: EMBL:AAH01198.1 xref: EMBL:AAH48210.1 xref: EMBL:AAK13046.1 xref: EMBL:AAK19748.1 xref: EMBL:CAI19247.1 xref: EMBL:CAI43145.1 xref: UniProtKB:Q5JWY9 xref: UniProtKB:Q9BVI0 xref: UniProtKB:Q9BWV4 xref: UniProtKB:Q9BXA3 xref: UniProtKB:Q9BZW3 xref: UniProtKB:Q9H421 xref: UniProtKB:Q9H4J6 xref: UniProtKB:Q9NZ22 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019380 ! PHF20_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069254 ! PHF20_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0069255 ! PHF20_HUMAN-Phosphoserine878 relationship: transforms_into CCO:B0069256 ! PHF20_HUMAN-Phosphoserine880 [Term] id: CCO:B0058528 name: Q9BVY9_HUMAN def: "ZNF160 protein" [UniProtKB:Q9BVY9] synonym: "Zinc finger protein 160, isoform CRA_a" EXACT [UniProtKB:Q9BVY9] xref: EMBL:AAH00807.1 xref: EMBL:EAW72110.1 xref: UniProtKB:Q9BVY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020635 ! ZNF160_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058529 name: MAD3_HUMAN def: "Max-interacting transcriptional repressor MAD3" [UniProtKB:Q9BW11] synonym: "MAX dimerization protein 3" EXACT [UniProtKB:Q9BW11] synonym: "Max-associated protein 3" EXACT [UniProtKB:Q9BW11] synonym: "Myx" EXACT [UniProtKB:Q9BW11] xref: EMBL:AAH00745.1 xref: EMBL:AAP97233.1 xref: EMBL:BAB71352.1 xref: EMBL:BAD96299.1 xref: EMBL:CAD38809.2 xref: UniProtKB:Q53HK1 xref: UniProtKB:Q7Z4Y0 xref: UniProtKB:Q8NDJ7 xref: UniProtKB:Q96ME3 xref: UniProtKB:Q9BW11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018555 ! MXD3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015008 ! magea11-mxd3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058530 name: RAYL_HUMAN def: "Putative GTP-binding protein RAY-like" [UniProtKB:Q9BW83] synonym: "Rab-like protein 4" EXACT [UniProtKB:Q9BW83] xref: EMBL:AAH00566.1 xref: EMBL:AAP35461.1 xref: EMBL:CAA18787.1 xref: EMBL:CAB62968.1 xref: EMBL:CAG30444.1 xref: UniProtKB:O60897 xref: UniProtKB:Q9BW83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019634 ! RABL4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015305 ! c1orf41-rabl4 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058531 name: REPI1_HUMAN def: "Replication initiator 1" [UniProtKB:Q9BWE0] synonym: "60 kDa origin-specific DNA-binding protein" EXACT [UniProtKB:Q9BWE0] synonym: "60 kDa replication initiation region protein" EXACT [UniProtKB:Q9BWE0] synonym: "ATT-binding protein" EXACT [UniProtKB:Q9BWE0] synonym: "DHFR oribeta-binding protein RIP60" EXACT [UniProtKB:Q9BWE0] synonym: "Zinc finger protein 464" EXACT [UniProtKB:Q9BWE0] xref: EMBL:AAF26712.1 xref: EMBL:AAH00363.2 xref: EMBL:AAH01760.1 xref: EMBL:AAS00385.1 xref: EMBL:AAS00386.1 xref: EMBL:CAB53100.1 xref: UniProtKB:Q7LE03 xref: UniProtKB:Q9BUZ6 xref: UniProtKB:Q9BWE0 xref: UniProtKB:Q9NZH2 xref: UniProtKB:Q9UMP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019672 ! REPIN1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000269 ! nuclear origin of replication recognition complex relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058532 name: TRAIP_HUMAN def: "TRAF-interacting protein" [UniProtKB:Q9BWF2] synonym: "RING finger protein 206" EXACT [UniProtKB:Q9BWF2] xref: EMBL:AAB52993.1 xref: EMBL:AAH00310.1 xref: EMBL:AAH19283.1 xref: UniProtKB:O00467 xref: UniProtKB:Q9BWF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020344 ! TRAIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0071529 ! TRAIP_HUMAN-Phosphoserine259 [Term] id: CCO:B0058533 name: Q9BWG3_HUMAN xref: UniProtKB:Q9BWG3 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058534 name: ZN416_HUMAN def: "Zinc finger protein 416" [UniProtKB:Q9BWM5] xref: EMBL:AAH00130.1 xref: EMBL:BAA91257.1 xref: UniProtKB:Q9BWM5 xref: UniProtKB:Q9NWW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020739 ! ZNF416_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058535 name: FAIM2_HUMAN def: "Fas apoptotic inhibitory molecule 2" [UniProtKB:Q9BWQ8] synonym: "Protein lifeguard" EXACT [UniProtKB:Q9BWQ8] synonym: "Transmembrane BAX inhibitor motif-containing protein 2" EXACT [UniProtKB:Q9BWQ8] xref: EMBL:AAF06327.1 xref: EMBL:AAH00051.1 xref: EMBL:BAA76794.1 xref: UniProtKB:Q9BWQ8 xref: UniProtKB:Q9UJY9 xref: UniProtKB:Q9Y2F7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017759 ! FAIM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 [Term] id: CCO:B0058536 name: CDCA7_HUMAN def: "Cell division cycle-associated protein 7" [UniProtKB:Q9BWT1] synonym: "Protein JPO1" EXACT [UniProtKB:Q9BWT1] xref: EMBL:AAH15124.1 xref: EMBL:AAH27966.1 xref: EMBL:AAK31591.1 xref: EMBL:AAX82003.1 xref: EMBL:BAB55245.1 xref: EMBL:BAB55258.1 xref: EMBL:BAC11425.1 xref: EMBL:BAD97244.1 xref: EMBL:CAH56253.1 xref: EMBL:CAH56357.1 xref: UniProtKB:Q53EW5 xref: UniProtKB:Q580W9 xref: UniProtKB:Q658K4 xref: UniProtKB:Q658N4 xref: UniProtKB:Q8NBY9 xref: UniProtKB:Q96BV8 xref: UniProtKB:Q96SP5 xref: UniProtKB:Q9BWT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017318 ! CDCA7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0058537 name: CAR10_HUMAN def: "Caspase recruitment domain-containing protein 10" [UniProtKB:Q9BWT7] synonym: "CARD-containing MAGUK protein 3" EXACT [UniProtKB:Q9BWT7] synonym: "Carma 3" EXACT [UniProtKB:Q9BWT7] xref: EMBL:AAI13660.1 xref: EMBL:AAK26165.1 xref: EMBL:AAK54454.1 xref: EMBL:CAI19345.1 xref: EMBL:CAI23165.1 xref: UniProtKB:Q14CQ8 xref: UniProtKB:Q5TFG6 xref: UniProtKB:Q9BWT7 xref: UniProtKB:Q9UGR5 xref: UniProtKB:Q9UGR6 xref: UniProtKB:Q9Y3H0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017227 ! CARD10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001453 ! CBM complex relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0058538 name: Q9BWW0_HUMAN def: "FKSG74" [UniProtKB:Q9BWW0] synonym: "HCG1809452, isoform CRA_a" EXACT [UniProtKB:Q9BWW0] xref: EMBL:AAK31778.1 xref: EMBL:EAW51523.1 xref: UniProtKB:Q9BWW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021256 ! FKSG74_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0058539 name: Q9BWW1_HUMAN def: "FKSG73 (FKSG73 protein, isoform CRA_a)" [UniProtKB:Q9BWW1] xref: EMBL:AAK31777.1 xref: EMBL:EAW50837.1 xref: UniProtKB:Q9BWW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021257 ! FKSG73_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0058540 name: Q9BWW2_HUMAN def: "FKSG72" [UniProtKB:Q9BWW2] xref: EMBL:AAK31776.1 xref: UniProtKB:Q9BWW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021258 ! FKSG72_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization [Term] id: CCO:B0058541 name: SSBP3_HUMAN def: "Single-stranded DNA-binding protein 3" [UniProtKB:Q9BWW4] synonym: "Sequence-specific single-stranded-DNA-binding protein" EXACT [UniProtKB:Q9BWW4] xref: EMBL:AAH03605.1 xref: EMBL:AAH66365.1 xref: EMBL:AAK21984.1 xref: EMBL:AAK21985.1 xref: EMBL:AAM22101.1 xref: UniProtKB:Q9BTM0 xref: UniProtKB:Q9BWW3 xref: UniProtKB:Q9BWW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020043 ! SSBP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070931 ! SSBP3_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0070932 ! SSBP3_HUMAN-Phosphothreonine360 relationship: transforms_into CCO:B0070933 ! SSBP3_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0070934 ! SSBP3_HUMAN-Phosphoserine387 [Term] id: CCO:B0058542 name: SCRT1_HUMAN def: "Transcriptional repressor scratch 1" [UniProtKB:Q9BWW7] synonym: "hScrt" EXACT [UniProtKB:Q9BWW7] synonym: "Scratch 1" EXACT [UniProtKB:Q9BWW7] synonym: "Scratch homolog 1 zinc finger protein" EXACT [UniProtKB:Q9BWW7] synonym: "SCRT" EXACT [UniProtKB:Q9BWW7] xref: EMBL:AAH14675.1 xref: EMBL:AAK01467.1 xref: EMBL:EAW82125.1 xref: UniProtKB:A8MX66 xref: UniProtKB:Q96C52 xref: UniProtKB:Q9BWW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019851 ! SCRT1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058543 name: GATA5_HUMAN def: "Transcription factor GATA-5" [UniProtKB:Q9BWX5] synonym: "GATA-binding factor 5" EXACT [UniProtKB:Q9BWX5] xref: EMBL:AAI17357.1 xref: EMBL:AAI17359.1 xref: EMBL:CAC36001.1 xref: UniProtKB:Q17RE2 xref: UniProtKB:Q9BWX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017873 ! GATA5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0058544 name: CARD6_HUMAN def: "Caspase recruitment domain-containing protein 6" [UniProtKB:Q9BX69] xref: EMBL:AAH93825.1 xref: EMBL:AAK32718.1 xref: EMBL:EAW56006.1 xref: UniProtKB:Q52LR2 xref: UniProtKB:Q9BX69 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017230 ! CARD6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0064068 ! CARD6_HUMAN-Phosphoserine468 [Term] id: CCO:B0058545 name: Q9BX81_HUMAN def: "FKSG83" [UniProtKB:Q9BX81] xref: EMBL:AAK32715.1 xref: UniProtKB:Q9BX81 xref: UniProtKB:Q9BXE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021259 ! FKSG83_human relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058546 name: ZN471_HUMAN def: "Zinc finger protein 471" [UniProtKB:Q9BX82] synonym: "EZFIT-related protein 1" EXACT [UniProtKB:Q9BX82] xref: EMBL:AAC32422.1 xref: EMBL:AAI25222.1 xref: EMBL:AAK30252.1 xref: EMBL:BAA92634.1 xref: EMBL:CAD38551.1 xref: UniProtKB:O75260 xref: UniProtKB:Q08AD7 xref: UniProtKB:Q8N3V1 xref: UniProtKB:Q9BX82 xref: UniProtKB:Q9P2F1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020766 ! ZNF471_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058547 name: SALL3_HUMAN def: "Sal-like protein 3" [UniProtKB:Q9BXA9] synonym: "hSALL3" EXACT [UniProtKB:Q9BXA9] synonym: "Zinc finger protein SALL3" EXACT [UniProtKB:Q9BXA9] xref: EMBL:AAK18311.1 xref: EMBL:CAB65124.1 xref: UniProtKB:Q9BXA9 xref: UniProtKB:Q9UGH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019834 ! SALL3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058548 name: LGR4_HUMAN def: "Leucine-rich repeat-containing G-protein coupled receptor 4 precursor" [UniProtKB:Q9BXB1] synonym: "G-protein coupled receptor 48" EXACT [UniProtKB:Q9BXB1] xref: EMBL:AAF68989.1 xref: EMBL:AAK31153.1 xref: EMBL:EAW68286.1 xref: UniProtKB:A6NCH3 xref: UniProtKB:Q9BXB1 xref: UniProtKB:Q9NYD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018481 ! LGR4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058549 name: GPR81_HUMAN def: "Probable G-protein coupled receptor 81" [UniProtKB:Q9BXC0] synonym: "G-protein coupled receptor 104" EXACT [UniProtKB:Q9BXC0] xref: EMBL:AAH66881.1 xref: EMBL:AAH66882.1 xref: EMBL:AAH66883.1 xref: EMBL:AAH67484.1 xref: EMBL:AAK29071.1 xref: EMBL:AAL26481.1 xref: EMBL:AAR92485.1 xref: EMBL:AAZ67915.1 xref: EMBL:BAB89344.1 xref: EMBL:BAC06084.1 xref: UniProtKB:Q3Y5J3 xref: UniProtKB:Q6NXU5 xref: UniProtKB:Q9BXC0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018033 ! GPR81_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058550 name: GP174_HUMAN def: "Probable G-protein coupled receptor 174" [UniProtKB:Q9BXC1] xref: EMBL:AAI04923.1 xref: EMBL:AAI04925.1 xref: EMBL:AAK29070.1 xref: EMBL:AAO92300.1 xref: EMBL:BAB89312.1 xref: EMBL:CAD13458.1 xref: UniProtKB:Q2M3F7 xref: UniProtKB:Q9BXC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017987 ! GPR174_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058551 name: VN1R3_HUMAN def: "Vomeronasal type-1 receptor 3" [UniProtKB:Q9BXE9] synonym: "V1r-like receptor 3" EXACT [UniProtKB:Q9BXE9] xref: EMBL:AAK21299.1 xref: UniProtKB:Q9BXE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020456 ! VN1R3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058552 name: CECR2_HUMAN def: "Cat eye syndrome critical region protein 2" [UniProtKB:Q9BXF3] xref: EMBL:AAK15343.1 xref: EMBL:AAL07393.1 xref: EMBL:BAB21831.1 xref: EMBL:CAH56122.1 xref: EMBL:CAH56212.1 xref: EMBL:EAW57756.1 xref: UniProtKB:A8MS90 xref: UniProtKB:A8MX16 xref: UniProtKB:Q658Z4 xref: UniProtKB:Q96P58 xref: UniProtKB:Q9BXF3 xref: UniProtKB:Q9C0C3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017327 ! CECR2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000647 ! DNA fragmentation during apoptosis [Term] id: CCO:B0058553 name: SPZ1_HUMAN def: "Spermatogenic leucine zipper protein 1" [UniProtKB:Q9BXG8] synonym: "Testis-specific protein 1" EXACT [UniProtKB:Q9BXG8] synonym: "Testis-specific protein NYD-TSP1" EXACT [UniProtKB:Q9BXG8] xref: EMBL:AAH33798.1 xref: EMBL:AAK17995.1 xref: EMBL:BAC05340.1 xref: UniProtKB:Q8N4P1 xref: UniProtKB:Q8N7E9 xref: UniProtKB:Q9BXG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020031 ! SPZ1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058554 name: TB10A_HUMAN def: "TBC1 domain family member 10A" [UniProtKB:Q9BXI6] synonym: "EBP50-PDX interactor of 64 kDa" EXACT [UniProtKB:Q9BXI6] synonym: "EPI64 protein" EXACT [UniProtKB:Q9BXI6] xref: EMBL:AAC23434.1 xref: EMBL:AAK35048.1 xref: EMBL:BAC11117.1 xref: UniProtKB:O76053 xref: UniProtKB:Q543A2 xref: UniProtKB:Q9BXI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020153 ! TBC1D10A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071167 ! TB10A_HUMAN-Phosphoserine407 [Term] id: CCO:B0058555 name: C1QT2_HUMAN def: "Complement C1q tumor necrosis factor-related protein 2 precursor" [UniProtKB:Q9BXJ5] xref: EMBL:AAH11699.1 xref: EMBL:AAH54506.1 xref: EMBL:AAK17960.1 xref: EMBL:AAQ89198.1 xref: UniProtKB:Q9BXJ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017194 ! C1QTNF2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0002522 ! positive regulation of glycogen biosynthetic process relationship: participates_in CCO:P0002687 ! positive regulation of fatty acid oxidation [Term] id: CCO:B0058556 name: NARG1_HUMAN def: "NMDA receptor-regulated protein 1" [UniProtKB:Q9BXJ9] synonym: "Gastric cancer antigen Ga19" EXACT [UniProtKB:Q9BXJ9] synonym: "N-terminal acetyltransferase" EXACT [UniProtKB:Q9BXJ9] synonym: "Protein tubedown-1" EXACT [UniProtKB:Q9BXJ9] synonym: "Tbdn100" EXACT [UniProtKB:Q9BXJ9] xref: EMBL:AAH39818.1 xref: EMBL:AAH93928.1 xref: EMBL:AAI04807.1 xref: EMBL:AAK15707.1 xref: EMBL:AAK68661.1 xref: EMBL:AAM48746.1 xref: EMBL:AAY40950.1 xref: EMBL:BAB14562.1 xref: EMBL:CAC43228.1 xref: UniProtKB:Q52LG9 xref: UniProtKB:Q8IWH4 xref: UniProtKB:Q8NEV2 xref: UniProtKB:Q9BXJ9 xref: UniProtKB:Q9H8P6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018720 ! NARG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068440 ! NARG1_HUMAN-Phosphoserine855 relationship: transforms_into CCO:B0068441 ! NARG1_HUMAN-Phosphoserine856 [Term] id: CCO:B0058557 name: KLF16_HUMAN def: "Krueppel-like factor 16" [UniProtKB:Q9BXK1] synonym: "Basic transcription element-binding protein 4" EXACT [UniProtKB:Q9BXK1] synonym: "BTE-binding protein 4" EXACT [UniProtKB:Q9BXK1] synonym: "Novel Sp1-like zinc finger transcription factor 2" EXACT [UniProtKB:Q9BXK1] synonym: "Transcription factor BTEB4" EXACT [UniProtKB:Q9BXK1] synonym: "Transcription factor NSLP2" EXACT [UniProtKB:Q9BXK1] xref: EMBL:AAK15698.1 xref: UniProtKB:Q9BXK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018414 ! KLF16_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway relationship: transforms_into CCO:B0067374 ! KLF16_HUMAN-Phosphoserine99 relationship: transforms_into CCO:B0067375 ! KLF16_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0067376 ! KLF16_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0067377 ! KLF16_HUMAN-Phosphothreonine152 [Term] id: CCO:B0058558 name: CAR14_HUMAN def: "Caspase recruitment domain-containing protein 14" [UniProtKB:Q9BXL6] synonym: "CARD-containing MAGUK protein 2" EXACT [UniProtKB:Q9BXL6] synonym: "Carma 2" EXACT [UniProtKB:Q9BXL6] xref: EMBL:AAG53403.1 xref: EMBL:AAH01326.1 xref: EMBL:AAH18142.1 xref: EMBL:AAK54453.1 xref: UniProtKB:Q9BVB5 xref: UniProtKB:Q9BXL6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017229 ! CARD14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000502 ! positive regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0064067 ! CAR14_HUMAN-Phosphoserine544 [Term] id: CCO:B0058559 name: CAR11_HUMAN def: "Caspase recruitment domain-containing protein 11" [UniProtKB:Q9BXL7] synonym: "CARD-containing MAGUK protein 3" EXACT [UniProtKB:Q9BXL7] synonym: "Carma 1" EXACT [UniProtKB:Q9BXL7] xref: EMBL:AAG53402.1 xref: EMBL:AAI11720.2 xref: EMBL:AAL34460.1 xref: EMBL:AAQ96893.1 xref: EMBL:EAL23962.1 xref: UniProtKB:A4D1Z7 xref: UniProtKB:Q2NKN7 xref: UniProtKB:Q548H3 xref: UniProtKB:Q9BXL7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017228 ! CARD11_human relationship: has_function CCO:F0000802 ! guanylate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008000 ! CARD domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002278 ! positive regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002391 ! regulation of B cell differentiation relationship: participates_in CCO:P0002394 ! regulation of T cell differentiation relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0058560 name: PINK1_HUMAN def: "Serine/threonine-protein kinase PINK1, mitochondrial precursor" [UniProtKB:Q9BXM7] synonym: "BRPK" EXACT [UniProtKB:Q9BXM7] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9BXM7] synonym: "PTEN-induced putative kinase protein 1" EXACT [UniProtKB:Q9BXM7] xref: EMBL:AAH09534.1 xref: EMBL:AAH28215.1 xref: EMBL:AAK28062.1 xref: EMBL:BAB55647.1 xref: EMBL:BAC11484.1 xref: EMBL:CAH73475.1 xref: UniProtKB:Q8N6T9 xref: UniProtKB:Q8NBU3 xref: UniProtKB:Q96DE4 xref: UniProtKB:Q9BXM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019400 ! PINK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000767 ! protein kinase cascade [Term] id: CCO:B0058561 name: CLC7A_HUMAN def: "C-type lectin domain family 7 member A" [UniProtKB:Q9BXN2] synonym: "Beta-glucan receptor" EXACT [UniProtKB:Q9BXN2] synonym: "C-type lectin superfamily member 12" EXACT [UniProtKB:Q9BXN2] synonym: "DC-associated C-type lectin 1" EXACT [UniProtKB:Q9BXN2] synonym: "Dectin-1" EXACT [UniProtKB:Q9BXN2] synonym: "Dendritic cell-associated C-type lectin 1" EXACT [UniProtKB:Q9BXN2] xref: EMBL:AAG33923.2 xref: EMBL:AAH71746.1 xref: EMBL:AAK20114.2 xref: EMBL:AAK20115.1 xref: EMBL:AAK20116.1 xref: EMBL:AAK37473.1 xref: EMBL:AAK37474.1 xref: EMBL:AAL11711.1 xref: EMBL:AAL11712.1 xref: EMBL:AAL11713.1 xref: EMBL:AAL11714.1 xref: EMBL:AAL11715.1 xref: EMBL:AAL11716.1 xref: EMBL:AAL11717.1 xref: EMBL:AAQ89361.1 xref: EMBL:CAC43846.1 xref: EMBL:CAC43847.1 xref: UniProtKB:Q6IPS7 xref: UniProtKB:Q96DR9 xref: UniProtKB:Q96LD3 xref: UniProtKB:Q96PA5 xref: UniProtKB:Q96PA6 xref: UniProtKB:Q96PA7 xref: UniProtKB:Q96PA8 xref: UniProtKB:Q9BXN2 xref: UniProtKB:Q9H1K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017381 ! CLEC7A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001838 ! pattern recognition receptor activity relationship: has_function CCO:F0005647 ! MHC protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000862 ! carbohydrate mediated signaling relationship: transforms_into CCO:B0064378 ! CLC7A_HUMAN-Phosphotyrosine15 relationship: transforms_into CCO:B0064379 ! CLC7A_HUMAN-Phosphoserine160 [Term] id: CCO:B0058562 name: PAPP2_HUMAN def: "Pappalysin-2 precursor" [UniProtKB:Q9BXP8] synonym: "EC 3.4.24.-" EXACT [UniProtKB:Q9BXP8] synonym: "PAPP-A2" EXACT [UniProtKB:Q9BXP8] synonym: "PAPP-E" EXACT [UniProtKB:Q9BXP8] synonym: "Pregnancy-associated plasma protein A2" EXACT [UniProtKB:Q9BXP8] synonym: "Pregnancy-associated plasma protein E1" EXACT [UniProtKB:Q9BXP8] xref: EMBL:AAK31073.1 xref: EMBL:AAL17779.1 xref: EMBL:AAL17780.1 xref: EMBL:CAC11134.1 xref: EMBL:CAH71731.1 xref: EMBL:CAI19567.1 xref: EMBL:CAI22172.1 xref: EMBL:CAI22721.1 xref: UniProtKB:Q96PH7 xref: UniProtKB:Q96PH8 xref: UniProtKB:Q9BXP8 xref: UniProtKB:Q9H4C9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019298 ! PAPPA2_human relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0058563 name: POK2_HUMAN def: "HERV-K_7p22.1 provirus ancestral Pol protein" [UniProtKB:Q9BXR3] synonym: "HERV-K(C7) Pol protein" EXACT [UniProtKB:Q9BXR3] synonym: "HERV-K(HML-2.HOM) Pol protein" EXACT [UniProtKB:Q9BXR3] synonym: "HERV-K108 Pol protein" EXACT [UniProtKB:Q9BXR3] xref: EMBL:AAC63293.1 xref: EMBL:AAD21097.1 xref: EMBL:AAD51797.1 xref: EMBL:AAF88167.1 xref: EMBL:AAK11553.1 xref: EMBL:AAK11554.1 xref: EMBL:CAA76879.1 xref: EMBL:CAA76885.1 xref: UniProtKB:Q6KH04 xref: UniProtKB:Q9BXR3 xref: UniProtKB:Q9BXR4 xref: UniProtKB:Q9UKH5 xref: UniProtKB:Q9UP31 xref: UniProtKB:Q9WIK9 xref: UniProtKB:Q9WJR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019468 ! ERVK6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0058564 name: AN30A_HUMAN def: "Ankyrin repeat domain-containing protein 30A" [UniProtKB:Q9BXX3] synonym: "Serologically defined breast cancer antigen NY-BR-1" EXACT [UniProtKB:Q9BXX3] xref: EMBL:AAK27325.1 xref: EMBL:CAH71320.1 xref: EMBL:CAI16567.1 xref: UniProtKB:Q5W025 xref: UniProtKB:Q9BXX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008442 ! ANKRD30A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058565 name: EMR3_HUMAN def: "EGF-like module-containing mucin-like hormone receptor-like 3 precursor" [UniProtKB:Q9BY15] synonym: "EGF-like module-containing mucin-like receptor EMR3" EXACT [UniProtKB:Q9BY15] xref: EMBL:AAK15076.1 xref: EMBL:AAQ89176.1 xref: UniProtKB:Q9BY15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017706 ! EMR3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0065058 ! EMR3_HUMAN-Phosphoserine141 relationship: transforms_into CCO:B0065059 ! EMR3_HUMAN-Phosphothreonine175 [Term] id: CCO:B0058566 name: M4A8B_HUMAN def: "Membrane-spanning 4-domains subfamily A member 8B" [UniProtKB:Q9BY19] synonym: "Four-span transmembrane protein 4" EXACT [UniProtKB:Q9BY19] xref: EMBL:AAH22895.1 xref: EMBL:AAK37414.1 xref: EMBL:AAL56224.1 xref: UniProtKB:Q8TCA5 xref: UniProtKB:Q9BY19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018549 ! MS4A8B_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058567 name: GPR87_HUMAN def: "Probable G-protein coupled receptor 87" [UniProtKB:Q9BY21] synonym: "G-protein coupled receptor 95" EXACT [UniProtKB:Q9BY21] xref: EMBL:AAH09540.2 xref: EMBL:AAK01858.1 xref: EMBL:AAK29069.1 xref: EMBL:AAL26485.1 xref: EMBL:BAB55366.1 xref: UniProtKB:Q96JZ8 xref: UniProtKB:Q9BXC2 xref: UniProtKB:Q9BY21 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018038 ! GPR87_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058568 name: ZN717_HUMAN def: "Zinc finger protein 717" [UniProtKB:Q9BY31] synonym: "Krueppel-like factor X17" EXACT [UniProtKB:Q9BY31] xref: EMBL:AAK28319.1 xref: UniProtKB:Q9BY31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020916 ! ZNF717_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072227 ! ZN717_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0072228 ! ZN717_HUMAN-Phosphothreonine396 relationship: transforms_into CCO:B0072229 ! ZN717_HUMAN-Phosphoserine398 relationship: transforms_into CCO:B0072230 ! ZN717_HUMAN-Phosphotyrosine402 [Term] id: CCO:B0058569 name: HDAC8_HUMAN def: "Histone deacetylase 8" [UniProtKB:Q9BY41] synonym: "EC 3.5.1.98" EXACT [UniProtKB:Q9BY41] synonym: "HD8" EXACT [UniProtKB:Q9BY41] xref: EMBL:AAF73076.1 xref: EMBL:AAF73428.1 xref: EMBL:AAK14930.1 xref: EMBL:CAB90213.1 xref: UniProtKB:A6NET3 xref: UniProtKB:Q9BY41 xref: UniProtKB:Q9NP76 xref: UniProtKB:Q9NYH4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018109 ! HDAC8_human relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058570 name: EIF2A_HUMAN def: "Eukaryotic translation initiation factor 2A" [UniProtKB:Q9BY44] synonym: "65 kDa eukaryotic translation initiation factor 2A" EXACT [UniProtKB:Q9BY44] synonym: "eIF-2A" EXACT [UniProtKB:Q9BY44] xref: EMBL:AAH11885.1 xref: EMBL:AAK14926.1 xref: EMBL:AAM83402.1 xref: EMBL:AAQ13506.1 xref: EMBL:AAQ13612.1 xref: EMBL:BAB55058.1 xref: UniProtKB:Q5QTR2 xref: UniProtKB:Q7Z4E9 xref: UniProtKB:Q8NFM1 xref: UniProtKB:Q96EW9 xref: UniProtKB:Q96K81 xref: UniProtKB:Q9BY44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017677 ! EIF2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0064948 ! EIF2A_HUMAN-Phosphoserine506 relationship: transforms_into CCO:B0064949 ! EIF2A_HUMAN-Phosphothreonine512 relationship: transforms_into CCO:B0064950 ! EIF2A_HUMAN-Phosphoserine517 relationship: transforms_into CCO:B0064951 ! EIF2A_HUMAN-Phosphothreonine518 relationship: transforms_into CCO:B0064952 ! EIF2A_HUMAN-Phosphothreonine522 [Term] id: CCO:B0058571 name: PECR_HUMAN def: "Peroxisomal trans-2-enoyl-CoA reductase" [UniProtKB:Q9BY49] synonym: "2,4-dienoyl-CoA reductase-related protein" EXACT [UniProtKB:Q9BY49] synonym: "DCR-RP" EXACT [UniProtKB:Q9BY49] synonym: "EC 1.3.1.38" EXACT [UniProtKB:Q9BY49] synonym: "HPDHase" EXACT [UniProtKB:Q9BY49] synonym: "pVI-ARL" EXACT [UniProtKB:Q9BY49] synonym: "TERP" EXACT [UniProtKB:Q9BY49] xref: EMBL:AAF69595.1 xref: EMBL:AAF69798.1 xref: EMBL:AAH02529.1 xref: EMBL:AAK14920.1 xref: EMBL:AAY14657.1 xref: EMBL:CAB89810.1 xref: EMBL:CAG33426.1 xref: UniProtKB:Q53TC4 xref: UniProtKB:Q6IAK9 xref: UniProtKB:Q9BY49 xref: UniProtKB:Q9NRD4 xref: UniProtKB:Q9NY60 xref: UniProtKB:Q9P1A4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019359 ! PECR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0069206 ! PECR_HUMAN-Phosphotyrosine179 [Term] id: CCO:B0058572 name: ANGL4_HUMAN def: "Angiopoietin-related protein 4 precursor" [UniProtKB:Q9BY76] synonym: "Angiopoietin-like 4" EXACT [UniProtKB:Q9BY76] synonym: "Hepatic fibrinogen/angiopoietin-related protein" EXACT [UniProtKB:Q9BY76] synonym: "HFARP" EXACT [UniProtKB:Q9BY76] xref: EMBL:AAD41088.1 xref: EMBL:AAF62868.1 xref: EMBL:AAG22490.1 xref: EMBL:AAH23647.1 xref: EMBL:AAQ88642.1 xref: EMBL:BAB40692.1 xref: EMBL:BAD96209.1 xref: EMBL:BAD96244.1 xref: UniProtKB:Q53HQ6 xref: UniProtKB:Q53HU1 xref: UniProtKB:Q6UXN0 xref: UniProtKB:Q9BY76 xref: UniProtKB:Q9HBV4 xref: UniProtKB:Q9NZU4 xref: UniProtKB:Q9Y5B3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016968 ! ANGPTL4_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0058573 name: SHAN3_HUMAN def: "SH3 and multiple ankyrin repeat domains protein 3" [UniProtKB:Q9BYB0] synonym: "Proline-rich synapse-associated protein 2" EXACT [UniProtKB:Q9BYB0] synonym: "ProSAP2" EXACT [UniProtKB:Q9BYB0] synonym: "Shank3" EXACT [UniProtKB:Q9BYB0] xref: EMBL:BAB33320.1 xref: EMBL:BAB84864.1 xref: UniProtKB:Q8TET3 xref: UniProtKB:Q9BYB0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019891 ! SHANK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: transforms_into CCO:B0070482 ! SHAN3_HUMAN-Phosphotyrosine122 relationship: transforms_into CCO:B0070483 ! SHAN3_HUMAN-Phosphoserine375 relationship: transforms_into CCO:B0070484 ! SHAN3_HUMAN-Phosphotyrosine557 relationship: transforms_into CCO:B0070485 ! SHAN3_HUMAN-Phosphotyrosine566 relationship: transforms_into CCO:B0070486 ! SHAN3_HUMAN-Phosphoserine783 relationship: transforms_into CCO:B0070487 ! SHAN3_HUMAN-Phosphoserine1159 relationship: transforms_into CCO:B0070488 ! SHAN3_HUMAN-Phosphoserine1163 relationship: transforms_into CCO:B0070489 ! SHAN3_HUMAN-Phosphoserine1644 [Term] id: CCO:B0058574 name: GNB1L_HUMAN def: "Guanine nucleotide-binding protein subunit beta-like protein 1" [UniProtKB:Q9BYB4] synonym: "DGCRK3" EXACT [UniProtKB:Q9BYB4] synonym: "G protein subunit beta-like protein 1" EXACT [UniProtKB:Q9BYB4] synonym: "Protein WDVCF" EXACT [UniProtKB:Q9BYB4] synonym: "WD repeat-containing protein 14" EXACT [UniProtKB:Q9BYB4] synonym: "WD40 repeat-containing protein deleted in VCFS" EXACT [UniProtKB:Q9BYB4] xref: EMBL:AAG12162.1 xref: EMBL:AAG36826.1 xref: EMBL:AAG53933.1 xref: EMBL:AAH12060.1 xref: EMBL:BAB33315.1 xref: EMBL:BAB68408.1 xref: EMBL:CAG30382.1 xref: UniProtKB:Q9BYB4 xref: UniProtKB:Q9H2S2 xref: UniProtKB:Q9H4M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017945 ! GNB1L_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000703 ! internal side of plasma membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058575 name: Q9BYD4_HUMAN def: "Fe65L2 isoform 214 (I-214)" [UniProtKB:Q9BYD4] xref: EMBL:BAB40806.1 xref: UniProtKB:Q9BYD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021260 ! Fe65L2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058576 name: HES7_HUMAN def: "Transcription factor HES-7" [UniProtKB:Q9BYE0] synonym: "bHLH factor Hes7" EXACT [UniProtKB:Q9BYE0] synonym: "Hairy and enhancer of split 7" EXACT [UniProtKB:Q9BYE0] xref: EMBL:BAB39525.1 xref: UniProtKB:Q9BYE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018123 ! HES7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066797 ! HES7_HUMAN-Phosphoserine170 [Term] id: CCO:B0058577 name: PCD24_HUMAN def: "Protocadherin-24 precursor" [UniProtKB:Q9BYE9] synonym: "PC-LKC" EXACT [UniProtKB:Q9BYE9] synonym: "Protocadherin LKC" EXACT [UniProtKB:Q9BYE9] xref: EMBL:BAA90962.1 xref: EMBL:BAB40777.1 xref: UniProtKB:A6NC80 xref: UniProtKB:Q9BYE9 xref: UniProtKB:Q9NXP8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019317 ! PCDH24_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0017673 ! mast2-pclkc-2 physical interaction relationship: participates_in CCO:I0017862 ! mast2-pclkc-1 physical interaction relationship: participates_in CCO:I0018174 ! mast2-pclkc-4 colocalization relationship: participates_in CCO:I0019490 ! mast2-pclkc-3 physical interaction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0058578 name: ACE2_HUMAN def: "Angiotensin-converting enzyme 2 precursor" [UniProtKB:Q9BYF1] synonym: "ACE-related carboxypeptidase" EXACT [UniProtKB:Q9BYF1] synonym: "ACEH" EXACT [UniProtKB:Q9BYF1] synonym: "Angiotensin-converting enzyme homolog" EXACT [UniProtKB:Q9BYF1] synonym: "EC 3.4.17.-" EXACT [UniProtKB:Q9BYF1] xref: EMBL:AAF78220.1 xref: EMBL:AAF99721.1 xref: EMBL:AAH39902.1 xref: EMBL:AAH48094.2 xref: EMBL:AAO25651.1 xref: EMBL:AAQ89076.1 xref: EMBL:AAT45083.1 xref: EMBL:BAB40370.1 xref: EMBL:BAD99266.1 xref: EMBL:BAD99267.1 xref: EMBL:CAB53682.1 xref: UniProtKB:Q6UWP0 xref: UniProtKB:Q86WT0 xref: UniProtKB:Q9BYF1 xref: UniProtKB:Q9NRA7 xref: UniProtKB:Q9UFZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016883 ! ACE2_human relationship: has_function CCO:F0000169 ! viral receptor activity relationship: has_function CCO:F0000251 ! glycoprotein binding relationship: has_function CCO:F0000649 ! carboxypeptidase activity relationship: has_function CCO:F0000692 ! peptidyl-dipeptidase A activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0058579 name: IKBZ_HUMAN def: "NF-kappa-B inhibitor zeta" [UniProtKB:Q9BYH8] synonym: "I-kappa-B-zeta" EXACT [UniProtKB:Q9BYH8] synonym: "IkappaBzeta" EXACT [UniProtKB:Q9BYH8] synonym: "IkB-zeta" EXACT [UniProtKB:Q9BYH8] synonym: "IL-1 inducible nuclear ankyrin-repeat protein" EXACT [UniProtKB:Q9BYH8] synonym: "INAP" EXACT [UniProtKB:Q9BYH8] synonym: "MAIL" EXACT [UniProtKB:Q9BYH8] synonym: "Molecule possessing ankyrin repeats induced by lipopolysaccharide" EXACT [UniProtKB:Q9BYH8] xref: EMBL:AAH60800.1 xref: EMBL:AAN40698.1 xref: EMBL:ABB02425.1 xref: EMBL:BAB40337.1 xref: EMBL:BAC03746.1 xref: EMBL:EAW79771.1 xref: UniProtKB:Q8IUL4 xref: UniProtKB:Q8NAZ8 xref: UniProtKB:Q9BYH8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018245 ! NFKBIZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058580 name: ZN341_HUMAN def: "Zinc finger protein 341" [UniProtKB:Q9BYN7] xref: EMBL:AAI32874.1 xref: EMBL:AAI46812.1 xref: EMBL:BAB55193.1 xref: EMBL:CAI21796.2 xref: UniProtKB:A2RUF4 xref: UniProtKB:Q5JXM8 xref: UniProtKB:Q96ST5 xref: UniProtKB:Q9BYN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020714 ! ZNF341_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058581 name: WNK3_HUMAN def: "Serine/threonine-protein kinase WNK3" [UniProtKB:Q9BYP7] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9BYP7] synonym: "Protein kinase with no lysine 3" EXACT [UniProtKB:Q9BYP7] synonym: "Protein kinase, lysine-deficient 3" EXACT [UniProtKB:Q9BYP7] xref: EMBL:AAL99253.1 xref: EMBL:AAR89465.1 xref: EMBL:BAB13392.1 xref: EMBL:CAC32455.2 xref: EMBL:CAI40708.1 xref: EMBL:CAI42733.1 xref: EMBL:CAI43129.1 xref: UniProtKB:Q5JRC1 xref: UniProtKB:Q6JP76 xref: UniProtKB:Q8TCX6 xref: UniProtKB:Q9BYP7 xref: UniProtKB:Q9HCK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020482 ! WNK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018726 ! wnk3-casp3-1 physical interaction relationship: participates_in CCO:I0019335 ! wnk3-casp3-2 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0071865 ! WNK3_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0071866 ! WNK3_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0071867 ! WNK3_HUMAN-Phosphoserine734 [Term] id: CCO:B0058582 name: PBX4_HUMAN def: "Pre-B-cell leukemia transcription factor 4" [UniProtKB:Q9BYU1] synonym: "Homeobox protein PBX4" EXACT [UniProtKB:Q9BYU1] xref: EMBL:BAG53471.1 xref: EMBL:CAC28212.1 xref: UniProtKB:B3KUK9 xref: UniProtKB:Q9BYU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019316 ! PBX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058583 name: TRI54_HUMAN def: "Tripartite motif-containing protein 54" [UniProtKB:Q9BYV2] synonym: "MuRF" EXACT [UniProtKB:Q9BYV2] synonym: "MURF-3" EXACT [UniProtKB:Q9BYV2] synonym: "MuRF3" EXACT [UniProtKB:Q9BYV2] synonym: "Muscle-specific RING finger protein" EXACT [UniProtKB:Q9BYV2] synonym: "Muscle-specific RING finger protein 3" EXACT [UniProtKB:Q9BYV2] synonym: "RING finger protein 30" EXACT [UniProtKB:Q9BYV2] xref: EMBL:AAI41808.1 xref: EMBL:AAY24296.1 xref: EMBL:CAC32841.1 xref: EMBL:CAC32842.1 xref: EMBL:EAX00606.1 xref: UniProtKB:A5D8T7 xref: UniProtKB:Q53SY4 xref: UniProtKB:Q9BYV2 xref: UniProtKB:Q9BYV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020357 ! TRIM54_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058584 name: TRI55_HUMAN def: "Tripartite motif-containing protein 55" [UniProtKB:Q9BYV6] synonym: "MURF-2" EXACT [UniProtKB:Q9BYV6] synonym: "MuRF2" EXACT [UniProtKB:Q9BYV6] synonym: "Muscle-specific RING finger protein 2" EXACT [UniProtKB:Q9BYV6] synonym: "RING finger protein 29" EXACT [UniProtKB:Q9BYV6] xref: EMBL:AAH07750.2 xref: EMBL:AAP35876.1 xref: EMBL:CAC32839.1 xref: EMBL:CAC32840.1 xref: EMBL:CAC43019.1 xref: EMBL:CAC43020.1 xref: EMBL:CAC81835.1 xref: EMBL:CAD24432.1 xref: UniProtKB:Q53XX3 xref: UniProtKB:Q8IUD9 xref: UniProtKB:Q8IUE4 xref: UniProtKB:Q96DV2 xref: UniProtKB:Q96DV3 xref: UniProtKB:Q9BYV5 xref: UniProtKB:Q9BYV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020358 ! TRIM55_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058585 name: BACH2_HUMAN def: "Transcription regulator protein BACH2" [UniProtKB:Q9BYV9] synonym: "BTB and CNC homolog 2" EXACT [UniProtKB:Q9BYV9] xref: EMBL:AAK48898.1 xref: EMBL:BAD92126.1 xref: EMBL:CAC28130.1 xref: EMBL:CAI16237.1 xref: EMBL:CAI21648.1 xref: UniProtKB:Q59H70 xref: UniProtKB:Q5T793 xref: UniProtKB:Q9BYV9 xref: UniProtKB:Q9NTS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017115 ! BACH2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058586 name: TBD2A_HUMAN def: "TBC1 domain family member 2A" [UniProtKB:Q9BYX2] synonym: "PARIS-1" EXACT [UniProtKB:Q9BYX2] synonym: "Prostate antigen recognized and identified by SEREX" EXACT [UniProtKB:Q9BYX2] xref: EMBL:AAK07684.1 xref: EMBL:CAH71887.1 xref: EMBL:CAI12580.1 xref: EMBL:CAI13885.1 xref: EMBL:EAW58882.1 xref: UniProtKB:Q5TBQ5 xref: UniProtKB:Q9BYX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020186 ! TBC1D2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071236 ! TBD2A_HUMAN-Phosphothreonine186 relationship: transforms_into CCO:B0071237 ! TBD2A_HUMAN-Phosphoserine436 relationship: transforms_into CCO:B0071238 ! TBD2A_HUMAN-Phosphoserine904 relationship: transforms_into CCO:B0071239 ! TBD2A_HUMAN-Phosphoserine909 [Term] id: CCO:B0058587 name: IFIH1_HUMAN def: "Interferon-induced helicase C domain-containing protein 1" [UniProtKB:Q9BYX4] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9BYX4] synonym: "Helicard" EXACT [UniProtKB:Q9BYX4] synonym: "Helicase with 2 CARD domains" EXACT [UniProtKB:Q9BYX4] synonym: "Interferon-induced with helicase C domain protein 1" EXACT [UniProtKB:Q9BYX4] synonym: "MDA-5" EXACT [UniProtKB:Q9BYX4] synonym: "Melanoma differentiation-associated protein 5" EXACT [UniProtKB:Q9BYX4] synonym: "Murabutide down-regulated protein" EXACT [UniProtKB:Q9BYX4] synonym: "RNA helicase-DEAD box protein 116" EXACT [UniProtKB:Q9BYX4] xref: EMBL:AAG34368.1 xref: EMBL:AAG54076.1 xref: EMBL:AAH46208.1 xref: EMBL:AAH78180.1 xref: EMBL:AAI11751.1 xref: EMBL:BAB71141.1 xref: UniProtKB:Q2NKL6 xref: UniProtKB:Q6DC96 xref: UniProtKB:Q86X56 xref: UniProtKB:Q96MX8 xref: UniProtKB:Q9BYX4 xref: UniProtKB:Q9H3G6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018233 ! IFIH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0067058 ! IFIH1_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0067059 ! IFIH1_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0067060 ! IFIH1_HUMAN-Phosphoserine645 [Term] id: CCO:B0058588 name: RHBT2_HUMAN def: "Rho-related BTB domain-containing protein 2" [UniProtKB:Q9BYZ6] synonym: "Deleted in breast cancer 2 gene protein" EXACT [UniProtKB:Q9BYZ6] synonym: "p83" EXACT [UniProtKB:Q9BYZ6] xref: EMBL:AAG61157.1 xref: EMBL:AAH34917.1 xref: EMBL:AAK07562.1 xref: EMBL:BAA34437.2 xref: UniProtKB:O94825 xref: UniProtKB:Q8N4A8 xref: UniProtKB:Q9BYZ6 xref: UniProtKB:Q9BZK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019711 ! RHOBTB2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058589 name: Q9BZ69_HUMAN def: "P143" [UniProtKB:Q9BZ69] xref: EMBL:AAK01301.1 xref: UniProtKB:Q9BZ69 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001044 ! protein histidine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058590 name: CNTP3_HUMAN def: "Contactin-associated protein-like 3 precursor" [UniProtKB:Q9BZ76] synonym: "Cell recognition molecule Caspr3" EXACT [UniProtKB:Q9BZ76] xref: EMBL:AAG52889.2 xref: EMBL:BAB21805.2 xref: EMBL:CAH70488.1 xref: EMBL:CAH72039.1 xref: UniProtKB:B1AMA0 xref: UniProtKB:Q9BZ76 xref: UniProtKB:Q9C0E9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017419 ! CNTNAP3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058591 name: Q9BZ77_HUMAN def: "FKSG41" [UniProtKB:Q9BZ77] xref: EMBL:AAG50292.1 xref: UniProtKB:Q9BZ77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021261 ! FKSG41_human relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058592 name: NSD3_HUMAN def: "Histone-lysine N-methyltransferase NSD3" [UniProtKB:Q9BZ95] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9BZ95] synonym: "Nuclear SET domain-containing protein 3" EXACT [UniProtKB:Q9BZ95] synonym: "Whistle" EXACT [UniProtKB:Q9BZ95] synonym: "WHSC1-like 1 isoform 9 with methyltransferase activity to lysine" EXACT [UniProtKB:Q9BZ95] synonym: "WHSC1-like protein 1" EXACT [UniProtKB:Q9BZ95] synonym: "Wolf-Hirschhorn syndrome candidate 1-like protein 1" EXACT [UniProtKB:Q9BZ95] xref: EMBL:AAG44637.1 xref: EMBL:AAH12059.1 xref: EMBL:AAH62631.1 xref: EMBL:AAI01718.1 xref: EMBL:AAI07735.1 xref: EMBL:AAI13470.1 xref: EMBL:AAI15007.1 xref: EMBL:AAK00354.1 xref: EMBL:AAK00355.1 xref: EMBL:BAA91110.1 xref: EMBL:BAB14099.1 xref: EMBL:BAC87049.1 xref: EMBL:CAC28350.1 xref: EMBL:CAC28351.1 xref: EMBL:CAC28352.1 xref: UniProtKB:Q1RMD3 xref: UniProtKB:Q3B796 xref: UniProtKB:Q6ZSA5 xref: UniProtKB:Q9BYU8 xref: UniProtKB:Q9BYU9 xref: UniProtKB:Q9BZ95 xref: UniProtKB:Q9H2M8 xref: UniProtKB:Q9H9W9 xref: UniProtKB:Q9NXA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018875 ! WHSC1L1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058593 name: CPEB1_HUMAN def: "Cytoplasmic polyadenylation element-binding protein 1" [UniProtKB:Q9BZB8] synonym: "CPE-binding protein 1" EXACT [UniProtKB:Q9BZB8] synonym: "CPE-BP1" EXACT [UniProtKB:Q9BZB8] synonym: "h-CEBP" EXACT [UniProtKB:Q9BZB8] synonym: "hCPEB-1" EXACT [UniProtKB:Q9BZB8] xref: EMBL:AAH35348.1 xref: EMBL:AAH50629.1 xref: EMBL:AAK01239.1 xref: EMBL:AAK01240.1 xref: EMBL:BAB14496.1 xref: UniProtKB:Q86W46 xref: UniProtKB:Q8IV41 xref: UniProtKB:Q9BZB7 xref: UniProtKB:Q9BZB8 xref: UniProtKB:Q9H8V5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017437 ! CPEB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0064449 ! CPEB1_HUMAN-Phosphothreonine172 [Term] id: CCO:B0058594 name: Q9BZC5_HUMAN def: "FKSG35" [UniProtKB:Q9BZC5] xref: EMBL:AAG50283.1 xref: UniProtKB:Q9BZC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021262 ! FKSG35_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058595 name: ABCA2_HUMAN def: "ATP-binding cassette sub-family A member 2" [UniProtKB:Q9BZC7] synonym: "ATP-binding cassette 2" EXACT [UniProtKB:Q9BZC7] synonym: "ATP-binding cassette transporter 2" EXACT [UniProtKB:Q9BZC7] xref: EMBL:AAK14335.1 xref: EMBL:BAA83014.2 xref: EMBL:BAD66832.1 xref: EMBL:CAI12768.1 xref: UniProtKB:A6NED5 xref: UniProtKB:Q5SPY5 xref: UniProtKB:Q5W9G5 xref: UniProtKB:Q76MW7 xref: UniProtKB:Q9BZC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016872 ! ABCA2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0065265 ! ABCA2_HUMAN-Phosphoserine1327 relationship: transforms_into CCO:B0065266 ! ABCA2_HUMAN-Phosphoserine1331 relationship: transforms_into CCO:B0065267 ! ABCA2_HUMAN-Phosphothreonine2412 [Term] id: CCO:B0058596 name: Q9BZD1_HUMAN def: "Ewings sarcoma EWS-Fli1 (Type 1) oncogene" [UniProtKB:Q9BZD1] xref: EMBL:AAK11227.1 xref: UniProtKB:Q9BZD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058597 name: BARH1_HUMAN def: "BarH-like 1 homeobox protein" [UniProtKB:Q9BZE3] xref: EMBL:AAG50279.1 xref: EMBL:AAK52674.1 xref: EMBL:BAB70807.1 xref: EMBL:CAB92439.1 xref: UniProtKB:Q9BZE3 xref: UniProtKB:Q9NY88 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017125 ! BARHL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058598 name: RAB34_HUMAN def: "Ras-related protein Rab-34" [UniProtKB:Q9BZG1] synonym: "Rab-39" EXACT [UniProtKB:Q9BZG1] synonym: "Ras-related protein Rah" EXACT [UniProtKB:Q9BZG1] xref: EMBL:AAH16841.1 xref: EMBL:AAH91510.1 xref: EMBL:AAK09397.1 xref: EMBL:AAP35348.1 xref: EMBL:BAB55034.1 xref: EMBL:BAC11141.1 xref: EMBL:CAC81760.1 xref: UniProtKB:Q5BJE6 xref: UniProtKB:Q8NCJ8 xref: UniProtKB:Q96AR4 xref: UniProtKB:Q9BZG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019589 ! RAB34_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069678 ! RAB34_HUMAN-Phosphoserine241 [Term] id: CCO:B0058599 name: Q9BZI2_HUMAN def: "Iroquois-related homeobox transcription factor" [UniProtKB:Q9BZI2] xref: EMBL:AAK01201.1 xref: UniProtKB:Q9BZI2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058600 name: GPR63_HUMAN def: "Probable G-protein coupled receptor 63" [UniProtKB:Q9BZJ6] synonym: "PSP24-2" EXACT [UniProtKB:Q9BZJ6] synonym: "PSP24-beta" EXACT [UniProtKB:Q9BZJ6] xref: EMBL:AAH67465.1 xref: EMBL:AAH67469.1 xref: EMBL:AAK12639.2 xref: EMBL:BAB20031.1 xref: EMBL:CAB55871.1 xref: UniProtKB:Q9BZJ6 xref: UniProtKB:Q9UJH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018029 ! GPR63_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058601 name: GPR62_HUMAN def: "Probable G-protein coupled receptor 62" [UniProtKB:Q9BZJ7] synonym: "hGPCR8" EXACT [UniProtKB:Q9BZJ7] xref: EMBL:AAK12638.1 xref: EMBL:BAB89303.1 xref: UniProtKB:Q9BZJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018028 ! GPR62_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058602 name: GPR61_HUMAN def: "Probable G-protein coupled receptor 61" [UniProtKB:Q9BZJ8] synonym: "Biogenic amine receptor-like G-protein coupled receptor" EXACT [UniProtKB:Q9BZJ8] xref: EMBL:AAH67464.1 xref: EMBL:AAK12637.1 xref: EMBL:AAK97826.1 xref: EMBL:BAB89298.1 xref: EMBL:CAI19302.1 xref: UniProtKB:Q6NWS0 xref: UniProtKB:Q8TDV4 xref: UniProtKB:Q96PR4 xref: UniProtKB:Q9BZJ8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018027 ! GPR61_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058603 name: Q9BZL0_HUMAN def: "Casp-2L-Pro" [UniProtKB:Q9BZL0] synonym: "Putative uncharacterized protein CASP2" EXACT [UniProtKB:Q9BZL0] xref: EMBL:AAK00299.1 xref: EMBL:AAP22348.1 xref: UniProtKB:Q9BZL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017235 ! CASP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0058604 name: KPCD2_HUMAN def: "Serine/threonine-protein kinase D2" [UniProtKB:Q9BZL6] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q9BZL6] synonym: "nPKC-D2" EXACT [UniProtKB:Q9BZL6] xref: EMBL:AAF36107.1 xref: EMBL:AAK01149.1 xref: EMBL:CAB43292.1 xref: UniProtKB:Q8TB08 xref: UniProtKB:Q9BZL6 xref: UniProtKB:Q9P0T6 xref: UniProtKB:Q9Y3X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018433 ! PRKD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0067399 ! KPCD2_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0067400 ! KPCD2_HUMAN-Phosphoserine198 relationship: transforms_into CCO:B0067401 ! KPCD2_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0067402 ! KPCD2_HUMAN-Phosphoserine203 relationship: transforms_into CCO:B0067403 ! KPCD2_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0067404 ! KPCD2_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0067405 ! KPCD2_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0067406 ! KPCD2_HUMAN-Phosphoserine710 relationship: transforms_into CCO:B0067407 ! KPCD2_HUMAN-Phosphoserine876 [Term] id: CCO:B0058605 name: B2L14_HUMAN def: "Apoptosis facilitator Bcl-2-like 14 protein" [UniProtKB:Q9BZR8] synonym: "Apoptosis regulator Bcl-G" EXACT [UniProtKB:Q9BZR8] xref: EMBL:AAG59793.1 xref: EMBL:AAG59794.1 xref: EMBL:AAH25778.1 xref: EMBL:AAK72109.1 xref: UniProtKB:Q96QR5 xref: UniProtKB:Q9BZR7 xref: UniProtKB:Q9BZR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017108 ! BCL2L14_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001745 ! intracellular organelle relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: transforms_into CCO:B0063689 ! B2L14_HUMAN-Phosphoserine152 [Term] id: CCO:B0058606 name: FOXP3_HUMAN def: "Forkhead box protein P3" [UniProtKB:Q9BZS1] synonym: "Scurfin" EXACT [UniProtKB:Q9BZS1] xref: EMBL:AAG53607.1 xref: EMBL:AAI13402.1 xref: EMBL:AAI13404.1 xref: EMBL:AAY27088.1 xref: EMBL:CAA06748.1 xref: UniProtKB:O60827 xref: UniProtKB:Q14DD8 xref: UniProtKB:Q4ZH51 xref: UniProtKB:Q9BZS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017826 ! FOXP3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003207 ! general transcriptional repressor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_function CCO:F0008131 ! NFAT protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0015986 ! foxp3-nfatc2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001541 ! negative regulation of NF-kappaB transcription factor activity relationship: participates_in CCO:P0001650 ! negative regulation of CREB transcription factor activity relationship: participates_in CCO:P0002031 ! negative regulation of cytokine biosynthetic process relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation relationship: participates_in CCO:P0002212 ! negative regulation of transcription factor activity relationship: participates_in CCO:P0002277 ! negative regulation of interleukin-2 biosynthetic process relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: participates_in CCO:P0002672 ! negative regulation of activated T cell proliferation [Term] id: CCO:B0058607 name: Q9BZT2_HUMAN def: "PNAS-32" [UniProtKB:Q9BZT2] xref: EMBL:AAK07532.1 xref: UniProtKB:Q9BZT2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058608 name: PO5L3_HUMAN xref: UniProtKB:Q9BZV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058609 name: PO5L4_HUMAN xref: UniProtKB:Q9BZW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058610 name: CD244_HUMAN def: "Natural killer cell receptor 2B4 precursor" [UniProtKB:Q9BZW8] synonym: "CD244 antigen" EXACT [UniProtKB:Q9BZW8] synonym: "h2B4" EXACT [UniProtKB:Q9BZW8] synonym: "NAIL" EXACT [UniProtKB:Q9BZW8] synonym: "NK cell activation-inducing ligand" EXACT [UniProtKB:Q9BZW8] synonym: "NK cell type I receptor protein 2B4" EXACT [UniProtKB:Q9BZW8] synonym: "NKR2B4" EXACT [UniProtKB:Q9BZW8] xref: EMBL:AAD32538.1 xref: EMBL:AAD37838.1 xref: EMBL:AAD38951.1 xref: EMBL:AAF28833.1 xref: EMBL:AAH28073.1 xref: EMBL:AAH53985.1 xref: EMBL:AAK00233.1 xref: EMBL:AAK50015.1 xref: EMBL:CAC00647.1 xref: EMBL:CAC00648.1 xref: EMBL:CAC00649.1 xref: UniProtKB:Q96T47 xref: UniProtKB:Q9BZW8 xref: UniProtKB:Q9NQD2 xref: UniProtKB:Q9NQD3 xref: UniProtKB:Q9Y288 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017291 ! CD244_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064141 ! CD244_HUMAN-Phosphotyrosine271 relationship: transforms_into CCO:B0064142 ! CD244_HUMAN-Phosphotyrosine369 [Term] id: CCO:B0058611 name: ROP1B_HUMAN def: "Ropporin-1B" [UniProtKB:Q9BZX4] synonym: "Rhophilin-associated protein 1B" EXACT [UniProtKB:Q9BZX4] xref: EMBL:AAG59586.1 xref: EMBL:AAH15413.1 xref: EMBL:AAI41850.1 xref: UniProtKB:Q96BM7 xref: UniProtKB:Q9BZX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019769 ! ROPN1B_human relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000896 ! flagellum relationship: participates_in CCO:P0000453 ! cytokinesis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction [Term] id: CCO:B0058612 name: API5_HUMAN def: "Apoptosis inhibitor 5" [UniProtKB:Q9BZZ5] synonym: "AAC-11" EXACT [UniProtKB:Q9BZZ5] synonym: "Antiapoptosis clone 11 protein" EXACT [UniProtKB:Q9BZZ5] synonym: "API-5" EXACT [UniProtKB:Q9BZZ5] synonym: "Cell migration-inducing gene 8 protein" EXACT [UniProtKB:Q9BZZ5] synonym: "Fibroblast growth factor 2-interacting factor" EXACT [UniProtKB:Q9BZZ5] synonym: "FIF" EXACT [UniProtKB:Q9BZZ5] synonym: "Protein XAGL" EXACT [UniProtKB:Q9BZZ5] xref: EMBL:AAB86528.1 xref: EMBL:AAH17709.1 xref: EMBL:AAK00737.1 xref: EMBL:AAK00738.1 xref: EMBL:AAO89077.1 xref: EMBL:AAP35756.1 xref: EMBL:AAQ76714.1 xref: EMBL:CAA75867.1 xref: UniProtKB:O15441 xref: UniProtKB:Q9BZZ5 xref: UniProtKB:Q9Y4J7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016989 ! API5_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003590 ! fibroblast growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0065691 ! API5_HUMAN-Phosphoserine464 [Term] id: CCO:B0058613 name: NALP1_HUMAN def: "NACHT, LRR and PYD domains-containing protein 1" [UniProtKB:Q9C000] synonym: "Caspase recruitment domain-containing protein 7" EXACT [UniProtKB:Q9C000] synonym: "Death effector filament-forming ced-4-like apoptosis protein" EXACT [UniProtKB:Q9C000] synonym: "Nucleotide-binding domain and caspase recruitment domain" EXACT [UniProtKB:Q9C000] xref: EMBL:AAG15254.1 xref: EMBL:AAG30288.1 xref: EMBL:AAK00748.1 xref: EMBL:AAK00749.1 xref: EMBL:AAK00750.1 xref: EMBL:AAK00751.1 xref: EMBL:BAA76770.2 xref: EMBL:CAB55945.1 xref: UniProtKB:Q9BZZ8 xref: UniProtKB:Q9BZZ9 xref: UniProtKB:Q9C000 xref: UniProtKB:Q9HAV8 xref: UniProtKB:Q9UFT4 xref: UniProtKB:Q9Y2E0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018710 ! NLRP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0058614 name: SPY4_HUMAN def: "Protein sprouty homolog 4" [UniProtKB:Q9C004] synonym: "Spry-4" EXACT [UniProtKB:Q9C004] xref: EMBL:AAK00652.1 xref: EMBL:AAK00653.1 xref: EMBL:AAS46253.1 xref: EMBL:BAC04798.1 xref: UniProtKB:Q6QIX2 xref: UniProtKB:Q9C003 xref: UniProtKB:Q9C004 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020030 ! SPRY4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017665 ! tesk1-spry4 physical interaction relationship: participates_in CCO:I0017666 ! spry4-tesk1 physical interaction relationship: participates_in CCO:I0018474 ! tesk1-spry4-2 physical interaction relationship: participates_in CCO:I0018475 ! tesk1-spry4-3 physical interaction relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: transforms_into CCO:B0070843 ! SPY4_HUMAN-Phosphoserine125 [Term] id: CCO:B0058615 name: ZFHX2_HUMAN def: "Zinc finger homeobox protein 2" [UniProtKB:Q9C0A1] synonym: "ZFH-2" EXACT [UniProtKB:Q9C0A1] synonym: "Zinc finger homeodomain protein 2" EXACT [UniProtKB:Q9C0A1] xref: EMBL:BAB21853.1 xref: UniProtKB:Q9C0A1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020582 ! ZFHX2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058616 name: Z518B_HUMAN def: "Zinc finger protein 518B" [UniProtKB:Q9C0D4] xref: EMBL:BAB21820.1 xref: EMBL:BAB71650.2 xref: UniProtKB:Q96LN8 xref: UniProtKB:Q9C0D4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020530 ! ZNF518B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058617 name: ASXL3_HUMAN def: "Putative Polycomb group protein ASXL3" [UniProtKB:Q9C0F0] synonym: "Additional sex combs-like protein 3" EXACT [UniProtKB:Q9C0F0] xref: EMBL:BAB21804.2 xref: EMBL:BAB71186.1 xref: EMBL:BAD18599.1 xref: EMBL:CAB61377.1 xref: UniProtKB:Q6ZMX6 xref: UniProtKB:Q96MU3 xref: UniProtKB:Q9C0F0 xref: UniProtKB:Q9UFC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017087 ! ASXL3_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058618 name: ZN436_HUMAN def: "Zinc finger protein 436" [UniProtKB:Q9C0F3] xref: EMBL:AAH56400.1 xref: EMBL:BAB21801.1 xref: EMBL:CAD39143.1 xref: EMBL:CAI19029.1 xref: UniProtKB:Q658I9 xref: UniProtKB:Q9C0F3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020749 ! ZNF436_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058619 name: ZN407_HUMAN def: "Zinc finger protein 407" [UniProtKB:Q9C0G0] xref: EMBL:BAA91077.1 xref: EMBL:BAA91080.1 xref: EMBL:BAB14716.1 xref: EMBL:BAB21794.1 xref: EMBL:BAB71139.1 xref: UniProtKB:Q96MY0 xref: UniProtKB:Q9C0G0 xref: UniProtKB:Q9H8A1 xref: UniProtKB:Q9NXD4 xref: UniProtKB:Q9NXD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020733 ! ZNF407_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058620 name: K1688_HUMAN def: "Uncharacterized protein KIAA1688" [UniProtKB:Q9C0H5] xref: EMBL:BAB21779.1 xref: UniProtKB:Q9C0H5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018371 ! KIAA1688_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067236 ! K1688_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0067237 ! K1688_HUMAN-Phosphoserine248 relationship: transforms_into CCO:B0067238 ! K1688_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0067239 ! K1688_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0067240 ! K1688_HUMAN-Phosphoserine604 [Term] id: CCO:B0058621 name: BHLH3_HUMAN def: "Class B basic helix-loop-helix protein 3" [UniProtKB:Q9C0J9] synonym: "bHLHB3" EXACT [UniProtKB:Q9C0J9] synonym: "Differentially expressed in chondrocytes protein 2" EXACT [UniProtKB:Q9C0J9] synonym: "Enhancer-of-split and hairy-related protein 1" EXACT [UniProtKB:Q9C0J9] synonym: "hDEC2" EXACT [UniProtKB:Q9C0J9] synonym: "SHARP-1" EXACT [UniProtKB:Q9C0J9] xref: EMBL:BAB21502.1 xref: UniProtKB:Q9C0J9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017146 ! BHLHB3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058622 name: BC11B_HUMAN def: "B-cell lymphoma/leukemia 11B" [UniProtKB:Q9C0K0] synonym: "B-cell CLL/lymphoma 11B" EXACT [UniProtKB:Q9C0K0] synonym: "COUP-TF-interacting protein 2" EXACT [UniProtKB:Q9C0K0] synonym: "hRit1" EXACT [UniProtKB:Q9C0K0] synonym: "Radiation-induced tumor suppressor gene 1 protein" EXACT [UniProtKB:Q9C0K0] xref: EMBL:BAB32731.1 xref: EMBL:CAC17726.1 xref: UniProtKB:Q9C0K0 xref: UniProtKB:Q9H162 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017136 ! BCL11B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058623 name: ARP11_HUMAN def: "Actin-related protein 11 precursor" [UniProtKB:Q9C0K3] xref: EMBL:BAB21501.1 xref: EMBL:CAI56711.1 xref: UniProtKB:Q5CZI4 xref: UniProtKB:Q9C0K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017045 ! ARP11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0001326 ! regulation of actin filament polymerization relationship: transforms_into CCO:B0063605 ! ARP11_HUMAN-Phosphotyrosine102 [Term] id: CCO:B0058624 name: OR2B2_HUMAN def: "Olfactory receptor 2B2" [UniProtKB:Q9GZK3] synonym: "Hs6M1-10" EXACT [UniProtKB:Q9GZK3] synonym: "Olfactory receptor 6-1" EXACT [UniProtKB:Q9GZK3] synonym: "OR6-1" EXACT [UniProtKB:Q9GZK3] xref: EMBL:CAC20504.1 xref: EMBL:CAC20505.1 xref: EMBL:CAC20506.1 xref: EMBL:CAC20507.1 xref: EMBL:CAC20508.1 xref: EMBL:CAC20509.1 xref: EMBL:CAC20510.1 xref: EMBL:CAC20511.1 xref: EMBL:CAC20512.1 xref: EMBL:CAC20513.1 xref: EMBL:CAD24079.1 xref: UniProtKB:Q9GZK3 xref: UniProtKB:Q9GZL2 xref: UniProtKB:Q9Y299 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019084 ! OR2B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058625 name: OR2H1_HUMAN def: "Olfactory receptor 2H1" [UniProtKB:Q9GZK4] synonym: "Hs6M1-16" EXACT [UniProtKB:Q9GZK4] synonym: "Olfactory receptor 6-2" EXACT [UniProtKB:Q9GZK4] synonym: "Olfactory receptor OR6-32" EXACT [UniProtKB:Q9GZK4] synonym: "OLFR42A-9004.14/9026.2" EXACT [UniProtKB:Q9GZK4] synonym: "OR6-2" EXACT [UniProtKB:Q9GZK4] xref: EMBL:AAC00184.1 xref: EMBL:AAC00188.1 xref: EMBL:AAC00189.1 xref: EMBL:AAH48991.1 xref: EMBL:CAB44506.1 xref: EMBL:CAC20524.1 xref: EMBL:CAC20525.1 xref: EMBL:CAC20526.1 xref: EMBL:CAC20527.1 xref: EMBL:CAC20528.1 xref: EMBL:CAC20529.1 xref: EMBL:CAC20530.1 xref: EMBL:CAC20531.1 xref: EMBL:CAC20532.1 xref: EMBL:CAC20533.1 xref: EMBL:CAD31039.1 xref: EMBL:CAI17486.1 xref: EMBL:CAI18055.1 xref: EMBL:CAI18457.1 xref: EMBL:CAM26161.1 xref: EMBL:DAA04607.1 xref: UniProtKB:O43629 xref: UniProtKB:O43661 xref: UniProtKB:O43662 xref: UniProtKB:Q5SUN6 xref: UniProtKB:Q9GZK4 xref: UniProtKB:Q9GZK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019097 ! OR2H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058626 name: OR2J1_HUMAN def: "Olfactory receptor 2J1" [UniProtKB:Q9GZK6] synonym: "Hs6M1-4" EXACT [UniProtKB:Q9GZK6] synonym: "Olfactory receptor 6-5" EXACT [UniProtKB:Q9GZK6] synonym: "OR6-5" EXACT [UniProtKB:Q9GZK6] xref: EMBL:CAC20485.1 xref: EMBL:CAC20486.1 xref: EMBL:CAC20487.1 xref: EMBL:CAC20488.1 xref: EMBL:CAC20489.1 xref: EMBL:CAC20490.1 xref: EMBL:CAI18101.2 xref: UniProtKB:A2AAS1 xref: UniProtKB:Q9GZK1 xref: UniProtKB:Q9GZK6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019100 ! OR2J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058627 name: O11A1_HUMAN def: "Olfactory receptor 11A1" [UniProtKB:Q9GZK7] synonym: "Hs6M1-18" EXACT [UniProtKB:Q9GZK7] synonym: "Olfactory receptor OR6-30" EXACT [UniProtKB:Q9GZK7] xref: EMBL:CAB44508.1 xref: EMBL:CAC20534.1 xref: EMBL:CAC20535.1 xref: EMBL:CAC20536.1 xref: EMBL:CAC20537.1 xref: EMBL:CAC20538.1 xref: EMBL:CAC20539.1 xref: EMBL:CAC20540.1 xref: EMBL:CAC20541.1 xref: EMBL:CAC20542.1 xref: EMBL:CAC20543.1 xref: EMBL:CAD31040.1 xref: EMBL:CAI17484.1 xref: EMBL:CAI18053.1 xref: EMBL:CAI95547.1 xref: EMBL:DAA04606.1 xref: EMBL:EAX03192.1 xref: UniProtKB:A6NFQ3 xref: UniProtKB:Q5ST16 xref: UniProtKB:Q9GZK7 xref: UniProtKB:Q9GZK8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018932 ! OR11A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058628 name: WDR12_HUMAN def: "WD repeat-containing protein 12" [UniProtKB:Q9GZL7] synonym: "YTM1 homolog" EXACT [UniProtKB:Q9GZL7] xref: EMBL:AAF60355.1 xref: EMBL:AAH08082.1 xref: EMBL:BAA91875.1 xref: EMBL:BAB14242.1 xref: EMBL:BAB14243.1 xref: UniProtKB:Q96HU0 xref: UniProtKB:Q9GZL7 xref: UniProtKB:Q9NV80 xref: UniProtKB:Q9NYI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020472 ! WDR12_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0058629 name: GPR88_HUMAN def: "Probable G-protein coupled receptor 88" [UniProtKB:Q9GZN0] synonym: "Striatum-specific G-protein coupled receptor" EXACT [UniProtKB:Q9GZN0] xref: EMBL:AAQ76787.1 xref: EMBL:BAB18247.1 xref: EMBL:BAB18248.1 xref: UniProtKB:Q6VN48 xref: UniProtKB:Q9GZN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018039 ! GPR88_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058630 name: VN1R1_HUMAN def: "Vomeronasal type-1 receptor 1" [UniProtKB:Q9GZP7] synonym: "hGPCR24" EXACT [UniProtKB:Q9GZP7] synonym: "V1r-like receptor 1" EXACT [UniProtKB:Q9GZP7] synonym: "V3r-related gene protein" EXACT [UniProtKB:Q9GZP7] synonym: "Vomeronasal olfactory receptor chromosome 19 subtype I member 1" EXACT [UniProtKB:Q9GZP7] xref: EMBL:AAG10698.1 xref: EMBL:AAG22545.1 xref: EMBL:AAH95508.1 xref: EMBL:AAP85612.1 xref: EMBL:AAP85613.1 xref: EMBL:AAP85614.1 xref: EMBL:BAB89319.1 xref: UniProtKB:Q7Z5H8 xref: UniProtKB:Q7Z5H9 xref: UniProtKB:Q9GZP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020454 ! VN1R1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003184 ! pheromone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058631 name: DERL2_HUMAN def: "Derlin-2" [UniProtKB:Q9GZP9] synonym: "Degradation in endoplasmic reticulum protein 2" EXACT [UniProtKB:Q9GZP9] synonym: "Der1-like protein 2" EXACT [UniProtKB:Q9GZP9] synonym: "DERtrin-2" EXACT [UniProtKB:Q9GZP9] synonym: "F-LAN-1" EXACT [UniProtKB:Q9GZP9] synonym: "F-LANa" EXACT [UniProtKB:Q9GZP9] xref: EMBL:AAD34096.1 xref: EMBL:AAF99603.1 xref: EMBL:AAG43049.1 xref: EMBL:AAH10890.1 xref: EMBL:AAL14869.1 xref: EMBL:CAG33483.1 xref: UniProtKB:Q9GZP9 xref: UniProtKB:Q9Y3A7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017559 ! DERL2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001254 ! positive regulation of cell growth relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response [Term] id: CCO:B0058632 name: NMUR2_HUMAN def: "Neuromedin-U receptor 2" [UniProtKB:Q9GZQ4] synonym: "G-protein coupled receptor FM-4" EXACT [UniProtKB:Q9GZQ4] synonym: "G-protein coupled receptor TGR-1" EXACT [UniProtKB:Q9GZQ4] synonym: "NMU-R2" EXACT [UniProtKB:Q9GZQ4] xref: EMBL:AAF82755.1 xref: EMBL:AAG03064.1 xref: EMBL:AAG24794.1 xref: EMBL:AAH16938.1 xref: EMBL:AAH67776.1 xref: EMBL:BAB13721.1 xref: UniProtKB:Q7LC54 xref: UniProtKB:Q96AM5 xref: UniProtKB:Q9GZQ4 xref: UniProtKB:Q9NRA6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018811 ! NMUR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000162 ! neuromedin U receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001504 ! intracellular calcium activated chloride channel activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0005747 ! neuromedin U binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002136 ! calcium-dependent phospholipase A2 activation relationship: participates_in CCO:P0002762 ! inositol phosphate-mediated signaling [Term] id: CCO:B0058633 name: NPFF1_HUMAN def: "Neuropeptide FF receptor 1" [UniProtKB:Q9GZQ6] synonym: "G-protein coupled receptor 147" EXACT [UniProtKB:Q9GZQ6] synonym: "RFamide-related peptide receptor OT7T022" EXACT [UniProtKB:Q9GZQ6] xref: EMBL:AAG41397.1 xref: EMBL:AAK94199.1 xref: EMBL:BAB17677.1 xref: EMBL:BAC05950.1 xref: UniProtKB:Q8NGR0 xref: UniProtKB:Q96RN3 xref: UniProtKB:Q9GZQ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018832 ! NPFFR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0068810 ! NPFF1_HUMAN-Phosphotyrosine216 relationship: transforms_into CCO:B0068811 ! NPFF1_HUMAN-Phosphothreonine218 relationship: transforms_into CCO:B0068812 ! NPFF1_HUMAN-Phosphotyrosine225 [Term] id: CCO:B0058634 name: REXO4_HUMAN def: "RNA exonuclease 4" [UniProtKB:Q9GZR2] synonym: "EC 3.1.-.-" EXACT [UniProtKB:Q9GZR2] synonym: "Exonuclease XPMC2" EXACT [UniProtKB:Q9GZR2] synonym: "hPMC2" EXACT [UniProtKB:Q9GZR2] synonym: "Prevents mitotic catastrophe 2 protein homolog" EXACT [UniProtKB:Q9GZR2] xref: EMBL:AAF98162.1 xref: EMBL:AAG02123.1 xref: EMBL:AAH09274.1 xref: EMBL:BAB15152.1 xref: EMBL:CAB66828.1 xref: EMBL:CAI12845.1 xref: EMBL:CAI12847.1 xref: EMBL:CAI12848.1 xref: EMBL:CAI12849.1 xref: UniProtKB:Q5T8S4 xref: UniProtKB:Q5T8S5 xref: UniProtKB:Q5T8S6 xref: UniProtKB:Q9GZR2 xref: UniProtKB:Q9GZW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019681 ! REXO4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069894 ! REXO4_HUMAN-Phosphoserine15 [Term] id: CCO:B0058635 name: SLIRP_HUMAN def: "SRA stem-loop-interacting RNA-binding protein, mitochondrial precursor" [UniProtKB:Q9GZT3] xref: EMBL:AAG44629.1 xref: EMBL:AAG44790.1 xref: EMBL:AAH17895.1 xref: EMBL:AAX58600.1 xref: EMBL:CAC81241.1 xref: UniProtKB:Q9GZT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019934 ! SLIRP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070577 ! SLIRP_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0070578 ! SLIRP_HUMAN-Phosphoserine102 [Term] id: CCO:B0058636 name: WN10A_HUMAN def: "Protein Wnt-10a precursor" [UniProtKB:Q9GZT5] xref: EMBL:AAG38660.1 xref: EMBL:AAG45153.1 xref: EMBL:AAH52234.1 xref: EMBL:BAB14898.1 xref: EMBL:BAB55602.1 xref: UniProtKB:Q96TA7 xref: UniProtKB:Q9GZT5 xref: UniProtKB:Q9H7S8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020478 ! WNT10A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058637 name: PEG3_HUMAN def: "Paternally-expressed gene 3 protein" [UniProtKB:Q9GZU2] synonym: "Zinc finger and SCAN domain-containing protein 24" EXACT [UniProtKB:Q9GZU2] xref: EMBL:AAB50011.1 xref: EMBL:AAC83176.1 xref: EMBL:AAG35739.1 xref: EMBL:AAG35740.1 xref: EMBL:AAG35741.1 xref: EMBL:AAG35742.1 xref: EMBL:AAG42324.1 xref: EMBL:AAG42325.1 xref: EMBL:AAH52616.1 xref: EMBL:BAB85588.1 xref: EMBL:CAI45975.1 xref: UniProtKB:P78418 xref: UniProtKB:Q5H9P9 xref: UniProtKB:Q7Z7H7 xref: UniProtKB:Q8TF75 xref: UniProtKB:Q9GZU2 xref: UniProtKB:Q9GZY2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019361 ! PEG3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058638 name: WWTR1_HUMAN def: "WW domain-containing transcription regulator protein 1" [UniProtKB:Q9GZV5] synonym: "Transcriptional coactivator with PDZ-binding motif" EXACT [UniProtKB:Q9GZV5] xref: EMBL:AAH14052.1 xref: EMBL:BAB13957.1 xref: EMBL:CAB43275.1 xref: EMBL:CAC17722.1 xref: EMBL:CAD38711.1 xref: UniProtKB:Q8N3P2 xref: UniProtKB:Q9GZV5 xref: UniProtKB:Q9Y3W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020503 ! WWTR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015361 ! q96bk2-wwtr1 physical interaction relationship: participates_in CCO:I0015668 ! tead3-wwtr1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002413 ! negative regulation of fat cell differentiation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0071884 ! WWTR1_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0071885 ! WWTR1_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0071886 ! WWTR1_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0071887 ! WWTR1_HUMAN-Phosphoserine105 [Term] id: CCO:B0058639 name: PRD14_HUMAN def: "PR domain zinc finger protein 14" [UniProtKB:Q9GZV8] synonym: "PR domain-containing protein 14" EXACT [UniProtKB:Q9GZV8] xref: EMBL:AAG39635.1 xref: EMBL:AAH52311.1 xref: EMBL:BAB14120.1 xref: UniProtKB:Q86UX9 xref: UniProtKB:Q9GZV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019490 ! PRDM14_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058640 name: FGF23_HUMAN def: "Fibroblast growth factor 23 precursor" [UniProtKB:Q9GZV9] synonym: "FGF-23" EXACT [UniProtKB:Q9GZV9] synonym: "Phosphatonin" EXACT [UniProtKB:Q9GZV9] synonym: "Tumor-derived hypophosphatemia-inducing factor" EXACT [UniProtKB:Q9GZV9] xref: EMBL:AAG09917.1 xref: EMBL:AAH69333.1 xref: EMBL:AAH96713.1 xref: EMBL:AAH98147.1 xref: EMBL:AAH98252.1 xref: EMBL:AAQ88689.1 xref: EMBL:AAS59157.1 xref: EMBL:BAB13477.1 xref: EMBL:BAB55889.1 xref: UniProtKB:Q4V758 xref: UniProtKB:Q9GZV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017800 ! FGF23_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0058641 name: ZN350_HUMAN def: "Zinc finger protein 350" [UniProtKB:Q9GZX5] synonym: "KRAB zinc finger protein ZFQR" EXACT [UniProtKB:Q9GZX5] synonym: "Zinc finger and BRCA1-interacting protein with a KRAB domain 1" EXACT [UniProtKB:Q9GZX5] synonym: "Zinc finger protein ZBRK1" EXACT [UniProtKB:Q9GZX5] xref: EMBL:AAG17439.1 xref: EMBL:AAG25714.1 xref: EMBL:AAH09921.1 xref: EMBL:BAB14583.1 xref: EMBL:EAW72056.1 xref: UniProtKB:Q96G73 xref: UniProtKB:Q9GZX5 xref: UniProtKB:Q9HAQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020717 ! ZNF350_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0058642 name: IL22_HUMAN def: "Interleukin-22 precursor" [UniProtKB:Q9GZX6] synonym: "IL-10-related T-cell-derived-inducible factor" EXACT [UniProtKB:Q9GZX6] synonym: "IL-22" EXACT [UniProtKB:Q9GZX6] synonym: "IL-TIF" EXACT [UniProtKB:Q9GZX6] xref: EMBL:AAG22064.1 xref: EMBL:AAH66263.1 xref: EMBL:AAH67510.1 xref: EMBL:AAH69112.1 xref: EMBL:AAH69308.1 xref: EMBL:AAH70261.1 xref: EMBL:AAK62468.1 xref: EMBL:AAQ89249.1 xref: EMBL:CAC06085.1 xref: EMBL:CAC19409.1 xref: UniProtKB:Q9GZX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018258 ! IL22_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006149 ! interleukin-22 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0002081 ! regulation of tyrosine phosphorylation of Stat3 protein [Term] id: CCO:B0058643 name: TWSG1_HUMAN def: "Twisted gastrulation protein homolog 1 precursor" [UniProtKB:Q9GZX9] xref: EMBL:AAG10076.1 xref: EMBL:AAG43468.1 xref: EMBL:AAH20490.1 xref: EMBL:BAB55246.1 xref: EMBL:BAC11693.1 xref: EMBL:CAC05581.1 xref: UniProtKB:Q8NBI7 xref: UniProtKB:Q96K46 xref: UniProtKB:Q9GZX9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020384 ! TWSG1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001274 ! positive regulation of BMP signaling pathway relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway relationship: participates_in CCO:P0002482 ! negative regulation of osteoblast differentiation [Term] id: CCO:B0058644 name: NTAL_HUMAN def: "Linker for activation of T-cells family member 2" [UniProtKB:Q9GZY6] synonym: "Linker for activation of B-cells" EXACT [UniProtKB:Q9GZY6] synonym: "Membrane-associated adapter molecule" EXACT [UniProtKB:Q9GZY6] synonym: "Non-T-cell activation linker" EXACT [UniProtKB:Q9GZY6] synonym: "Williams-Beuren syndrome chromosomal region 15 protein" EXACT [UniProtKB:Q9GZY6] xref: EMBL:AAF29018.1 xref: EMBL:AAF74978.1 xref: EMBL:AAF91352.1 xref: EMBL:AAH01609.1 xref: EMBL:AAH06080.1 xref: EMBL:AAH09204.1 xref: EMBL:AAK37429.1 xref: EMBL:AAK37430.1 xref: EMBL:AAK37431.1 xref: EMBL:AAK37633.1 xref: EMBL:AAO63155.1 xref: EMBL:AAS07404.1 xref: EMBL:AAS07405.1 xref: EMBL:BAA92084.1 xref: EMBL:BAF83605.1 xref: EMBL:BAG52627.1 xref: EMBL:EAW69610.1 xref: UniProtKB:A6NFK6 xref: UniProtKB:A8K4F1 xref: UniProtKB:Q9BXX8 xref: UniProtKB:Q9GZY6 xref: UniProtKB:Q9NZY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018880 ! LAT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017597 ! ubqln4-lat2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002971 ! B cell receptor signaling pathway relationship: transforms_into CCO:B0068872 ! NTAL_HUMAN-Phosphotyrosine58 relationship: transforms_into CCO:B0068873 ! NTAL_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0068874 ! NTAL_HUMAN-Phosphotyrosine136 relationship: transforms_into CCO:B0068875 ! NTAL_HUMAN-Phosphotyrosine193 relationship: transforms_into CCO:B0068876 ! NTAL_HUMAN-Phosphotyrosine233 [Term] id: CCO:B0058645 name: HXD1_HUMAN def: "Homeobox protein Hox-D1" [UniProtKB:Q9GZZ0] xref: EMBL:AAG29939.1 xref: EMBL:AAG44444.1 xref: UniProtKB:Q9GZZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018193 ! HOXD1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058646 name: ACH10_HUMAN def: "Neuronal acetylcholine receptor subunit alpha-10 precursor" [UniProtKB:Q9GZZ6] synonym: "NACHR alpha 10" EXACT [UniProtKB:Q9GZZ6] synonym: "Nicotinic acetylcholine receptor subunit alpha 10" EXACT [UniProtKB:Q9GZZ6] xref: EMBL:AAG00795.2 xref: EMBL:AAK14333.1 xref: EMBL:CAC16144.1 xref: EMBL:CAC20435.1 xref: UniProtKB:Q9GZZ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016886 ! CHRNA10_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0058647 name: Q9H023_HUMAN xref: UniProtKB:Q9H023 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0058648 name: PAIP1_HUMAN def: "Polyadenylate-binding protein-interacting protein 1" [UniProtKB:Q9H074] synonym: "PABP-interacting protein 1" EXACT [UniProtKB:Q9H074] synonym: "PAIP-1" EXACT [UniProtKB:Q9H074] synonym: "Poly(A)-binding protein-interacting protein 1" EXACT [UniProtKB:Q9H074] xref: EMBL:AAC39697.2 xref: EMBL:AAH05295.1 xref: EMBL:AAH15937.1 xref: EMBL:CAB66854.1 xref: UniProtKB:O60455 xref: UniProtKB:Q96B61 xref: UniProtKB:Q9BS63 xref: UniProtKB:Q9H074 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019292 ! PAIP1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001952 ! translation activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018357 ! pabp-paip1 2 physical interaction relationship: participates_in CCO:I0018358 ! paip1-pabp 2 physical interaction relationship: participates_in CCO:I0018861 ! pabp-paip1 3 direct interaction relationship: participates_in CCO:I0018862 ! paip1-pabp 3 direct interaction relationship: participates_in CCO:I0019286 ! pabp-paip1 physical interaction relationship: participates_in CCO:I0019287 ! paip1-pabp physical interaction relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0002800 ! mRNA stabilization [Term] id: CCO:B0058649 name: RB33B_HUMAN def: "Ras-related protein Rab-33B" [UniProtKB:Q9H082] xref: EMBL:AAI11978.1 xref: EMBL:AAL83916.1 xref: EMBL:AAY40936.1 xref: EMBL:CAB66838.1 xref: UniProtKB:Q4W5B0 xref: UniProtKB:Q9H082 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019637 ! RAB33B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069759 ! RB33B_HUMAN-Cysteine methyl ester229 [Term] id: CCO:B0058650 name: SP130_HUMAN def: "Histone deacetylase complex subunit SAP130" [UniProtKB:Q9H0E3] synonym: "130 kDa Sin3-associated polypeptide" EXACT [UniProtKB:Q9H0E3] synonym: "Sin3-associated polypeptide p130" EXACT [UniProtKB:Q9H0E3] xref: EMBL:AAH17453.2 xref: EMBL:AAI17256.1 xref: EMBL:AAO63591.1 xref: EMBL:AAX88975.1 xref: EMBL:AAY14878.1 xref: EMBL:BAB14261.1 xref: EMBL:CAB66767.1 xref: UniProtKB:Q4ZFV4 xref: UniProtKB:Q53T46 xref: UniProtKB:Q8WVW4 xref: UniProtKB:Q9H0E3 xref: UniProtKB:Q9H9G8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019998 ! SAP130_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070769 ! SP130_HUMAN-Phosphothreonine355 relationship: transforms_into CCO:B0070770 ! SP130_HUMAN-Phosphoserine442 relationship: transforms_into CCO:B0070771 ! SP130_HUMAN-Phosphoserine454 relationship: transforms_into CCO:B0070772 ! SP130_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0070773 ! SP130_HUMAN-Phosphoserine875 [Term] id: CCO:B0058651 name: BRD8_HUMAN def: "Bromodomain-containing protein 8" [UniProtKB:Q9H0E9] synonym: "p120" EXACT [UniProtKB:Q9H0E9] synonym: "Skeletal muscle abundant protein" EXACT [UniProtKB:Q9H0E9] synonym: "Skeletal muscle abundant protein 2" EXACT [UniProtKB:Q9H0E9] synonym: "Thyroid hormone receptor coactivating protein 120kDa" EXACT [UniProtKB:Q9H0E9] synonym: "TrCP120" EXACT [UniProtKB:Q9H0E9] xref: EMBL:AAB87858.1 xref: EMBL:AAH08039.1 xref: EMBL:AAH08076.1 xref: EMBL:BAD92316.1 xref: EMBL:CAA60949.1 xref: EMBL:CAA63925.1 xref: EMBL:CAB66757.1 xref: UniProtKB:O43178 xref: UniProtKB:Q15355 xref: UniProtKB:Q58AB0 xref: UniProtKB:Q59GN0 xref: UniProtKB:Q969M9 xref: UniProtKB:Q9H0E9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017178 ! BRD8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0063986 ! BRD8_HUMAN-Phosphoserine637 relationship: transforms_into CCO:B0063987 ! BRD8_HUMAN-Phosphoserine641 relationship: transforms_into CCO:B0063988 ! BRD8_HUMAN-Phosphothreonine1151 relationship: transforms_into CCO:B0063989 ! BRD8_HUMAN-Phosphoserine1152 [Term] id: CCO:B0058652 name: ARL6_HUMAN def: "ADP-ribosylation factor-like protein 6" [UniProtKB:Q9H0F7] synonym: "Bardet-Biedl syndrome 3 protein" EXACT [UniProtKB:Q9H0F7] xref: EMBL:AAH24239.1 xref: EMBL:CAB66749.1 xref: UniProtKB:Q9H0F7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017040 ! ARL6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058653 name: WWP1_HUMAN def: "NEDD4-like E3 ubiquitin-protein ligase WWP1" [UniProtKB:Q9H0M0] synonym: "AIP5" EXACT [UniProtKB:Q9H0M0] synonym: "Atropin-1-interacting protein 5" EXACT [UniProtKB:Q9H0M0] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9H0M0] synonym: "WW domain-containing protein 1" EXACT [UniProtKB:Q9H0M0] xref: EMBL:AAC51324.1 xref: EMBL:AAH15380.2 xref: EMBL:AAH36065.1 xref: EMBL:AAK94668.1 xref: EMBL:CAB66673.1 xref: UniProtKB:O00307 xref: UniProtKB:Q96BP4 xref: UniProtKB:Q9H0M0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020502 ! WWP1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015033 ! wwp1-znf638 physical interaction relationship: participates_in CCO:I0015147 ! ewsr1-wwp1 physical interaction relationship: participates_in CCO:I0015762 ! dazap2-wwp1 physical interaction relationship: participates_in CCO:I0018932 ! atn1-wwp1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0071882 ! WWP1_HUMAN-Phosphothreonine822 [Term] id: CCO:B0058654 name: ZN700_HUMAN def: "Zinc finger protein 700" [UniProtKB:Q9H0M5] xref: EMBL:CAB66666.1 xref: UniProtKB:Q9H0M5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020906 ! ZNF700_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058655 name: RAB6C_HUMAN def: "Ras-related protein Rab-6C" [UniProtKB:Q9H0N0] synonym: "Rab6-like protein WTH3" EXACT [UniProtKB:Q9H0N0] xref: EMBL:AAF28422.1 xref: EMBL:AAI21000.1 xref: EMBL:AAN39685.1 xref: EMBL:AAY15045.1 xref: EMBL:CAB66661.1 xref: EMBL:CAG38500.1 xref: EMBL:EAW95362.1 xref: EMBL:EAX11700.1 xref: UniProtKB:Q53RU3 xref: UniProtKB:Q6FIF7 xref: UniProtKB:Q9H0N0 xref: UniProtKB:Q9P128 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019604 ! RAB6C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058656 name: PHS2_HUMAN def: "Pterin-4-alpha-carbinolamine dehydratase 2" [UniProtKB:Q9H0N5] synonym: "4-alpha-hydroxy-tetrahydropterin dehydratase 2" EXACT [UniProtKB:Q9H0N5] synonym: "DcoH-like protein DCoHm" EXACT [UniProtKB:Q9H0N5] synonym: "Dimerization cofactor of hepatocyte nuclear factor 1 from muscle" EXACT [UniProtKB:Q9H0N5] synonym: "EC 4.2.1.96" EXACT [UniProtKB:Q9H0N5] synonym: "HNF-1-alpha dimerization cofactor" EXACT [UniProtKB:Q9H0N5] synonym: "PHS 2" EXACT [UniProtKB:Q9H0N5] xref: EMBL:AAH54021.1 xref: EMBL:AAM18136.1 xref: EMBL:CAB66655.1 xref: UniProtKB:Q8TD40 xref: UniProtKB:Q9H0N5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019385 ! PCBD2_human relationship: has_function CCO:F0000902 ! phenylalanine 4-monooxygenase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001729 ! 4-alpha-hydroxytetrahydrobiopterin dehydratase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017746 ! dyrk1b-dcohm-1 physical interaction relationship: participates_in CCO:I0018323 ! dyrk1b-dcohm-2 direct interaction relationship: participates_in CCO:I0018324 ! dyrk1b-dcohm-3 physical interaction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0058657 name: RAB17_HUMAN def: "Ras-related protein Rab-17" [UniProtKB:Q9H0T7] xref: EMBL:AAH00929.1 xref: EMBL:AAH50426.1 xref: EMBL:BAB14121.1 xref: EMBL:CAB66580.1 xref: UniProtKB:Q9BVU1 xref: UniProtKB:Q9H0T7 xref: UniProtKB:Q9H9U9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019574 ! RAB17_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020388 ! nudt3-rab17 physical interaction relationship: participates_in CCO:I0020662 ! s100a8-rab17 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058658 name: ATG10_HUMAN def: "Autophagy-related protein 10" [UniProtKB:Q9H0Y0] synonym: "APG10-like" EXACT [UniProtKB:Q9H0Y0] xref: EMBL:AAH29268.1 xref: EMBL:AAL55833.1 xref: EMBL:BAB14778.1 xref: EMBL:CAB66846.1 xref: UniProtKB:Q6PIX1 xref: UniProtKB:Q9H0Y0 xref: UniProtKB:Q9H842 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017096 ! ATG10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001435 ! positive regulation of protein modification process relationship: participates_in CCO:P0001958 ! autophagy in response to ER overload [Term] id: CCO:B0058659 name: GZF1_HUMAN def: "GDNF-inducible zinc finger protein 1" [UniProtKB:Q9H116] synonym: "Zinc finger and BTB domain-containing protein 23" EXACT [UniProtKB:Q9H116] synonym: "Zinc finger protein 336" EXACT [UniProtKB:Q9H116] xref: EMBL:BAB15134.1 xref: EMBL:BAB71107.1 xref: EMBL:BAC98464.1 xref: EMBL:CAC03438.2 xref: UniProtKB:Q54A22 xref: UniProtKB:Q96N08 xref: UniProtKB:Q9BQK9 xref: UniProtKB:Q9H116 xref: UniProtKB:Q9H117 xref: UniProtKB:Q9H6W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018095 ! GZF1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058660 name: ALX4_HUMAN def: "Homeobox protein aristaless-like 4" [UniProtKB:Q9H161] xref: EMBL:AAG23961.1 xref: EMBL:AAK38835.1 xref: EMBL:BAB47417.1 xref: EMBL:CAC15060.1 xref: EMBL:CAC15120.1 xref: UniProtKB:Q96JN7 xref: UniProtKB:Q9H161 xref: UniProtKB:Q9H198 xref: UniProtKB:Q9HAY9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016956 ! ALX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058661 name: CSRN2_HUMAN def: "Cysteine/serine-rich nuclear protein 2" [UniProtKB:Q9H175] synonym: "CSRNP-2" EXACT [UniProtKB:Q9H175] synonym: "Protein FAM130A1" EXACT [UniProtKB:Q9H175] synonym: "TAIP-12" EXACT [UniProtKB:Q9H175] synonym: "TGF-beta-induced apoptosis protein 12" EXACT [UniProtKB:Q9H175] xref: EMBL:AAH17221.1 xref: EMBL:BAB79451.2 xref: EMBL:CAC22252.1 xref: UniProtKB:Q9H175 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017484 ! CSRNP2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058662 name: SDCB2_HUMAN def: "Syntenin-2" [UniProtKB:Q9H190] synonym: "Syndecan-binding protein 2" EXACT [UniProtKB:Q9H190] xref: EMBL:AAD20049.1 xref: EMBL:AAF80369.1 xref: EMBL:AAH02727.2 xref: EMBL:CAC16178.1 xref: EMBL:CAC21573.1 xref: EMBL:CAC21716.1 xref: EMBL:CAH72383.1 xref: UniProtKB:O95892 xref: UniProtKB:Q5W0X1 xref: UniProtKB:Q9BZ42 xref: UniProtKB:Q9H190 xref: UniProtKB:Q9H567 xref: UniProtKB:Q9NRY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019858 ! SDCBP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0015038 ! mmtag2-sdcbp2 physical interaction relationship: participates_in CCO:I0015152 ! sdcbp2-tifa physical interaction relationship: participates_in CCO:I0015247 ! ps1d-sdcbp2 physical interaction relationship: participates_in CCO:I0015483 ! pafah1b3-sdcbp2 physical interaction relationship: participates_in CCO:I0015549 ! dkfzp564j157-sdcbp2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058663 name: LPAR5_HUMAN def: "Lysophosphatidic acid receptor 5" [UniProtKB:Q9H1C0] synonym: "G-protein coupled receptor 92" EXACT [UniProtKB:Q9H1C0] synonym: "G-protein coupled receptor 93" EXACT [UniProtKB:Q9H1C0] synonym: "LPA receptor 5" EXACT [UniProtKB:Q9H1C0] synonym: "LPA-5" EXACT [UniProtKB:Q9H1C0] xref: EMBL:AAH33571.1 xref: EMBL:AAH72394.1 xref: EMBL:AAL26483.1 xref: EMBL:BAB89313.1 xref: EMBL:CAC03715.1 xref: UniProtKB:Q9H1C0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022376 ! LPAR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058664 name: Q9H1C9_HUMAN def: "Putative small GTP-binding protein (Rab1b)" [UniProtKB:Q9H1C9] xref: EMBL:CAC21570.1 xref: UniProtKB:Q9H1C9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058665 name: WNT8A_HUMAN def: "Protein Wnt-8a precursor" [UniProtKB:Q9H1J5] synonym: "Wnt-8d" EXACT [UniProtKB:Q9H1J5] xref: EMBL:AAG38662.1 xref: EMBL:BAB60960.1 xref: UniProtKB:Q96S51 xref: UniProtKB:Q9H1J5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020495 ! WNT8A_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058666 name: WNT5B_HUMAN def: "Protein Wnt-5b precursor" [UniProtKB:Q9H1J7] xref: EMBL:AAG38659.1 xref: EMBL:AAH01749.1 xref: EMBL:BAB62039.1 xref: UniProtKB:Q96S49 xref: UniProtKB:Q9BV04 xref: UniProtKB:Q9H1J7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020491 ! WNT5B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:I0015432 ! appbp2-wnt5b physical interaction relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058667 name: OPN3_HUMAN def: "Opsin-3" [UniProtKB:Q9H1Y3] synonym: "Encephalopsin" EXACT [UniProtKB:Q9H1Y3] synonym: "Panopsin" EXACT [UniProtKB:Q9H1Y3] xref: EMBL:AAD32671.1 xref: EMBL:AAH36773.1 xref: EMBL:AAK37447.1 xref: EMBL:AAO15715.1 xref: EMBL:AAO15717.1 xref: UniProtKB:Q8IX08 xref: UniProtKB:Q9H1Y3 xref: UniProtKB:Q9Y344 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019049 ! OPN3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001680 ! G-protein coupled photoreceptor activity relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058668 name: O2AG1_HUMAN def: "Olfactory receptor 2AG1" [UniProtKB:Q9H205] synonym: "HT3" EXACT [UniProtKB:Q9H205] xref: EMBL:AAG45209.1 xref: EMBL:AAK95103.1 xref: EMBL:BAC06042.1 xref: UniProtKB:Q96R26 xref: UniProtKB:Q9H205 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018958 ! OR2AG1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058669 name: O10A5_HUMAN def: "Olfactory receptor 10A5" [UniProtKB:Q9H207] synonym: "HP3" EXACT [UniProtKB:Q9H207] synonym: "Olfactory receptor 11-403" EXACT [UniProtKB:Q9H207] synonym: "Olfactory receptor-like protein JCG6" EXACT [UniProtKB:Q9H207] synonym: "OR11-403" EXACT [UniProtKB:Q9H207] xref: EMBL:AAC70019.1 xref: EMBL:AAG45206.1 xref: EMBL:AAH93651.1 xref: EMBL:AAH93653.1 xref: EMBL:AAK95108.1 xref: EMBL:AAL33005.1 xref: UniProtKB:O95223 xref: UniProtKB:Q52M66 xref: UniProtKB:Q96R21 xref: UniProtKB:Q96R22 xref: UniProtKB:Q9H207 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018900 ! OR10A5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058670 name: O10A2_HUMAN def: "Olfactory receptor 10A2" [UniProtKB:Q9H208] synonym: "HP4" EXACT [UniProtKB:Q9H208] synonym: "Olfactory receptor OR11-86" EXACT [UniProtKB:Q9H208] xref: EMBL:AAG45207.1 xref: EMBL:AAK95109.1 xref: EMBL:DAA04691.1 xref: UniProtKB:Q6IFG9 xref: UniProtKB:Q9H208 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018897 ! OR10A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058671 name: O10A4_HUMAN def: "Olfactory receptor 10A4" [UniProtKB:Q9H209] synonym: "HP2" EXACT [UniProtKB:Q9H209] synonym: "Olfactory receptor-like protein JCG5" EXACT [UniProtKB:Q9H209] xref: EMBL:AAG45205.1 xref: EMBL:AAK95110.1 xref: EMBL:AAL32993.1 xref: UniProtKB:Q96R20 xref: UniProtKB:Q9H209 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018899 ! OR10A4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058672 name: OR2D2_HUMAN def: "Olfactory receptor 2D2" [UniProtKB:Q9H210] synonym: "HB2" EXACT [UniProtKB:Q9H210] synonym: "Olfactory receptor 11-610" EXACT [UniProtKB:Q9H210] synonym: "Olfactory receptor OR11-88" EXACT [UniProtKB:Q9H210] synonym: "OR11-610" EXACT [UniProtKB:Q9H210] xref: EMBL:AAC70020.1 xref: EMBL:AAG45204.1 xref: EMBL:AAK95076.1 xref: EMBL:BAC06043.1 xref: EMBL:DAA04832.1 xref: UniProtKB:O95224 xref: UniProtKB:Q6IF28 xref: UniProtKB:Q8NGH4 xref: UniProtKB:Q96R52 xref: UniProtKB:Q9H210 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019091 ! OR2D2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058673 name: S1PR5_HUMAN def: "Sphingosine 1-phosphate receptor 5" [UniProtKB:Q9H228] synonym: "Endothelial differentiation G-protein-coupled receptor 8" EXACT [UniProtKB:Q9H228] synonym: "S1P receptor 5" EXACT [UniProtKB:Q9H228] synonym: "S1P receptor Edg-8" EXACT [UniProtKB:Q9H228] synonym: "S1P5" EXACT [UniProtKB:Q9H228] synonym: "Sphingosine 1-phosphate receptor Edg-8" EXACT [UniProtKB:Q9H228] xref: EMBL:AAG38113.1 xref: EMBL:AAH34703.1 xref: EMBL:AAH67781.1 xref: EMBL:AAL57041.1 xref: EMBL:AAP20653.1 xref: EMBL:BAB89315.1 xref: EMBL:BAC11119.1 xref: UniProtKB:Q6NW11 xref: UniProtKB:Q9H228 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022628 ! S1PR5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058674 name: PORCN_HUMAN def: "Probable protein-cysteine N-palmitoyltransferase porcupine" [UniProtKB:Q9H237] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q9H237] synonym: "Protein MG61" EXACT [UniProtKB:Q9H237] xref: EMBL:AAA74510.1 xref: EMBL:AAG39628.1 xref: EMBL:AAG39629.1 xref: EMBL:AAG39630.1 xref: EMBL:AAG39631.1 xref: EMBL:AAH19080.1 xref: UniProtKB:Q14829 xref: UniProtKB:Q9H234 xref: UniProtKB:Q9H235 xref: UniProtKB:Q9H236 xref: UniProtKB:Q9H237 xref: UniProtKB:Q9UJU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019470 ! PORCN_human relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058675 name: P2Y12_HUMAN def: "P2Y purinoceptor 12" [UniProtKB:Q9H244] synonym: "ADP-glucose receptor" EXACT [UniProtKB:Q9H244] synonym: "ADPG-R" EXACT [UniProtKB:Q9H244] synonym: "P2T(AC)" EXACT [UniProtKB:Q9H244] synonym: "P2Y(AC)" EXACT [UniProtKB:Q9H244] synonym: "P2Y(ADP)" EXACT [UniProtKB:Q9H244] synonym: "P2Y(cyc)" EXACT [UniProtKB:Q9H244] synonym: "P2Y12" EXACT [UniProtKB:Q9H244] synonym: "P2Y12 platelet ADP receptor" EXACT [UniProtKB:Q9H244] synonym: "SP1999" EXACT [UniProtKB:Q9H244] xref: EMBL:AAG48944.1 xref: EMBL:AAH17898.1 xref: EMBL:AAK00948.1 xref: EMBL:AAL32292.1 xref: EMBL:AAN01280.1 xref: EMBL:BAB60824.1 xref: EMBL:BAB89309.1 xref: EMBL:CAC87144.1 xref: UniProtKB:Q546J7 xref: UniProtKB:Q9H244 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019272 ! P2RY12_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000164 ! adenosine receptor activity, G-protein coupled relationship: has_function CCO:F0000171 ! platelet ADP receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:B0058676 name: KCNH6_HUMAN def: "Potassium voltage-gated channel subfamily H member 6" [UniProtKB:Q9H252] synonym: "Eag-related protein 2" EXACT [UniProtKB:Q9H252] synonym: "Ether-a-go-go-related gene potassium channel 2" EXACT [UniProtKB:Q9H252] synonym: "Ether-a-go-go-related protein 2" EXACT [UniProtKB:Q9H252] synonym: "Voltage-gated potassium channel subunit Kv11.2" EXACT [UniProtKB:Q9H252] xref: EMBL:AAG40871.1 xref: EMBL:AAH06334.1 xref: EMBL:BAC03559.1 xref: EMBL:BAC03764.1 xref: UniProtKB:Q9BRD7 xref: UniProtKB:Q9H252 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018395 ! KCNH6_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058677 name: SPTN4_HUMAN def: "Spectrin beta chain, brain 3" [UniProtKB:Q9H254] synonym: "Beta-IV spectrin" EXACT [UniProtKB:Q9H254] synonym: "Spectrin, non-erythroid beta chain 3" EXACT [UniProtKB:Q9H254] xref: EMBL:AAF93171.1 xref: EMBL:AAF93172.1 xref: EMBL:AAF93173.1 xref: EMBL:AAG38874.1 xref: EMBL:AAG42473.1 xref: EMBL:BAB13468.1 xref: UniProtKB:Q9H1K7 xref: UniProtKB:Q9H1K8 xref: UniProtKB:Q9H1K9 xref: UniProtKB:Q9H254 xref: UniProtKB:Q9H3G8 xref: UniProtKB:Q9HCD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020026 ! SPTBN4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018089 ! disc1-spectrin-2 physical interaction relationship: participates_in CCO:I0018370 ! disc1-spectrin-1 physical interaction relationship: participates_in CCO:I0018546 ! disc1-spectrin physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0070839 ! SPTN4_HUMAN-Phosphothreonine2111 relationship: transforms_into CCO:B0070840 ! SPTN4_HUMAN-Phosphothreonine2112 relationship: transforms_into CCO:B0070841 ! SPTN4_HUMAN-Phosphoserine2121 [Term] id: CCO:B0058678 name: O51E2_HUMAN def: "Olfactory receptor 51E2" [UniProtKB:Q9H255] synonym: "HPRAJ" EXACT [UniProtKB:Q9H255] synonym: "Olfactory receptor OR11-16" EXACT [UniProtKB:Q9H255] synonym: "Prostate-specific G-protein coupled receptor" EXACT [UniProtKB:Q9H255] xref: EMBL:AAG40776.1 xref: EMBL:AAH20768.1 xref: EMBL:AAK38728.1 xref: EMBL:AAK57550.1 xref: EMBL:DAA04766.1 xref: UniProtKB:Q6IF94 xref: UniProtKB:Q9H255 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018989 ! OR51E2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058679 name: CARD9_HUMAN def: "Caspase recruitment domain-containing protein 9" [UniProtKB:Q9H257] synonym: "hCARD9" EXACT [UniProtKB:Q9H257] xref: EMBL:AAG28790.1 xref: EMBL:AAH08877.1 xref: EMBL:BAB14766.1 xref: EMBL:CAI13931.1 xref: UniProtKB:Q5SXM6 xref: UniProtKB:Q9H257 xref: UniProtKB:Q9H854 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017232 ! CARD9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008000 ! CARD domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001695 ! positive regulation of stress-activated MAPK cascade relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: transforms_into CCO:B0064069 ! CARD9_HUMAN-Phosphoserine460 [Term] id: CCO:B0058680 name: LHX5_HUMAN def: "LIM/homeobox protein Lhx5" [UniProtKB:Q9H2C1] synonym: "LIM homeobox protein 5" EXACT [UniProtKB:Q9H2C1] xref: EMBL:AAG36963.1 xref: EMBL:AAI09231.1 xref: UniProtKB:Q32MA4 xref: UniProtKB:Q9H2C1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018488 ! LHX5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0067644 ! LHX5_HUMAN-Phosphotyrosine119 [Term] id: CCO:B0058681 name: O52A5_HUMAN def: "Olfactory receptor 52A5" [UniProtKB:Q9H2C5] synonym: "Odorant receptor HOR3'beta5" EXACT [UniProtKB:Q9H2C5] synonym: "Olfactory receptor OR11-33" EXACT [UniProtKB:Q9H2C5] xref: EMBL:AAG42368.1 xref: EMBL:DAA04831.1 xref: UniProtKB:Q9H2C5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019004 ! OR52A5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058682 name: Q9H2C6_HUMAN def: "Odorant receptor HOR3'beta3" [UniProtKB:Q9H2C6] xref: EMBL:AAG42366.1 xref: UniProtKB:Q9H2C6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058683 name: O51V1_HUMAN def: "Olfactory receptor 51V1" [UniProtKB:Q9H2C8] synonym: "Odorant receptor HOR3'beta1" EXACT [UniProtKB:Q9H2C8] synonym: "Olfactory receptor OR11-36" EXACT [UniProtKB:Q9H2C8] xref: EMBL:AAG42364.1 xref: EMBL:DAA04830.1 xref: UniProtKB:Q9H2C8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019001 ! OR51V1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058684 name: TARA_HUMAN def: "TRIO and F-actin-binding protein" [UniProtKB:Q9H2D6] synonym: "Protein Tara" EXACT [UniProtKB:Q9H2D6] synonym: "Trio-associated repeat on actin" EXACT [UniProtKB:Q9H2D6] xref: EMBL:AAG44841.1 xref: EMBL:AAH03618.1 xref: EMBL:AAH04303.1 xref: EMBL:AAH13278.2 xref: EMBL:ABB59559.1 xref: EMBL:ABB59560.1 xref: EMBL:ABB59561.1 xref: EMBL:ABB77204.1 xref: EMBL:BAA34800.1 xref: EMBL:BAB33332.2 xref: EMBL:CAQ09783.1 xref: EMBL:CAQ09786.1 xref: UniProtKB:B1AHD4 xref: UniProtKB:B1AHD7 xref: UniProtKB:O94797 xref: UniProtKB:Q2PZW8 xref: UniProtKB:Q2Q3Z9 xref: UniProtKB:Q2Q400 xref: UniProtKB:Q5R3M6 xref: UniProtKB:Q96DW1 xref: UniProtKB:Q9BT77 xref: UniProtKB:Q9BTL7 xref: UniProtKB:Q9BY98 xref: UniProtKB:Q9H2D6 xref: UniProtKB:Q9Y3L4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020149 ! TRIOBP_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003532 ! GTP-Rho binding relationship: has_function CCO:F0006091 ! myosin II binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:I0020029 ! triobp-vim physical interaction relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping relationship: transforms_into CCO:B0071129 ! TARA_HUMAN-Phosphothreonine810 relationship: transforms_into CCO:B0071130 ! TARA_HUMAN-Phosphoserine1949 relationship: transforms_into CCO:B0071131 ! TARA_HUMAN-Phosphoserine1955 [Term] id: CCO:B0058685 name: SEM6A_HUMAN def: "Semaphorin-6A precursor" [UniProtKB:Q9H2E6] synonym: "Sema VIA" EXACT [UniProtKB:Q9H2E6] synonym: "SEMA6A-1" EXACT [UniProtKB:Q9H2E6] synonym: "Semaphorin VIA" EXACT [UniProtKB:Q9H2E6] synonym: "Semaphorin-6A-1" EXACT [UniProtKB:Q9H2E6] xref: EMBL:AAG29378.1 xref: EMBL:BAA92606.1 xref: UniProtKB:Q9H2E6 xref: UniProtKB:Q9P2H9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019868 ! SEMA6A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001004 ! axon relationship: participates_in CCO:I0017300 ! sema6a-kiaa0777 physical interaction relationship: participates_in CCO:I0017301 ! sema6a-itsn2 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0058686 name: CXXC4_HUMAN def: "CXXC-type zinc finger protein 4" [UniProtKB:Q9H2H0] synonym: "Inhibition of the Dvl and axin complex protein" EXACT [UniProtKB:Q9H2H0] xref: EMBL:AAG42072.1 xref: EMBL:AAI19752.1 xref: EMBL:AAI19753.1 xref: EMBL:AAY40933.1 xref: EMBL:EAX06175.1 xref: UniProtKB:Q9H2H0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017507 ! CXXC4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0058687 name: IF3M_HUMAN def: "Translation initiation factor IF-3, mitochondrial precursor" [UniProtKB:Q9H2K0] synonym: "IF-3(Mt)" EXACT [UniProtKB:Q9H2K0] synonym: "IF-3Mt" EXACT [UniProtKB:Q9H2K0] synonym: "IF3(mt)" EXACT [UniProtKB:Q9H2K0] synonym: "IF3mt" EXACT [UniProtKB:Q9H2K0] xref: EMBL:AAG44698.1 xref: EMBL:AAH39599.1 xref: EMBL:AAH46166.1 xref: EMBL:AAL04150.1 xref: EMBL:CAH70316.1 xref: UniProtKB:Q05BL8 xref: UniProtKB:Q5W0V0 xref: UniProtKB:Q86X68 xref: UniProtKB:Q9H2K0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018225 ! MTIF3_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0005786 ! ribosomal small subunit binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000661 ! regulation of translational initiation [Term] id: CCO:B0058688 name: ADNP_HUMAN def: "Activity-dependent neuroprotector homeobox protein" [UniProtKB:Q9H2P0] synonym: "Activity-dependent neuroprotective protein" EXACT [UniProtKB:Q9H2P0] xref: EMBL:AAG47651.1 xref: EMBL:AAH90933.1 xref: EMBL:BAA34504.1 xref: EMBL:CAB45752.1 xref: EMBL:CAB53748.2 xref: UniProtKB:O94881 xref: UniProtKB:Q5BKU2 xref: UniProtKB:Q9H2P0 xref: UniProtKB:Q9UG34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016920 ! ADNP_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065426 ! ADNP_HUMAN-Phosphoserine98 relationship: transforms_into CCO:B0065427 ! ADNP_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0065428 ! ADNP_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0065429 ! ADNP_HUMAN-Phosphoserine709 relationship: transforms_into CCO:B0065430 ! ADNP_HUMAN-Phosphoserine736 relationship: transforms_into CCO:B0065431 ! ADNP_HUMAN-Phosphoserine876 relationship: transforms_into CCO:B0065432 ! ADNP_HUMAN-Phosphoserine878 relationship: transforms_into CCO:B0065433 ! ADNP_HUMAN-Phosphoserine953 relationship: transforms_into CCO:B0065434 ! ADNP_HUMAN-Phosphoserine955 [Term] id: CCO:B0058689 name: M4A6A_HUMAN def: "Membrane-spanning 4-domains subfamily A member 6A" [UniProtKB:Q9H2W1] synonym: "CD20 antigen" EXACT [UniProtKB:Q9H2W1] synonym: "CD20 antigen-like 3" EXACT [UniProtKB:Q9H2W1] synonym: "Four-span transmembrane protein 3" EXACT [UniProtKB:Q9H2W1] xref: EMBL:AAG27920.1 xref: EMBL:AAG41780.1 xref: EMBL:AAG44626.1 xref: EMBL:AAG44672.1 xref: EMBL:AAH22854.1 xref: EMBL:AAK37417.1 xref: EMBL:AAK37994.1 xref: EMBL:AAL07357.1 xref: EMBL:AAL56222.1 xref: EMBL:AAL56223.1 xref: EMBL:BAB18740.1 xref: UniProtKB:Q8TBV7 xref: UniProtKB:Q8TEZ4 xref: UniProtKB:Q8TEZ5 xref: UniProtKB:Q96PG6 xref: UniProtKB:Q9H2L1 xref: UniProtKB:Q9H2N3 xref: UniProtKB:Q9H2W1 xref: UniProtKB:Q9H3V1 xref: UniProtKB:Q9HC76 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018547 ! MS4A6A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058690 name: MIXL1_HUMAN def: "Homeobox protein MIXL1" [UniProtKB:Q9H2W2] synonym: "hMix" EXACT [UniProtKB:Q9H2W2] synonym: "Homeodomain protein MIX" EXACT [UniProtKB:Q9H2W2] synonym: "Mix.1 homeobox-like protein" EXACT [UniProtKB:Q9H2W2] synonym: "MIX1 homeobox-like protein 1" EXACT [UniProtKB:Q9H2W2] xref: EMBL:AAG35776.1 xref: EMBL:AAI11975.1 xref: EMBL:AAI13442.1 xref: EMBL:AAK01479.1 xref: EMBL:CAH71924.1 xref: EMBL:EAW69778.1 xref: UniProtKB:Q9H2W2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018628 ! MIXL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068205 ! MIXL1_HUMAN-Phosphotyrosine20 [Term] id: CCO:B0058691 name: CLC4M_HUMAN def: "C-type lectin domain family 4 member M" [UniProtKB:Q9H2X3] synonym: "CD209 antigen-like protein 1" EXACT [UniProtKB:Q9H2X3] synonym: "CD299 antigen" EXACT [UniProtKB:Q9H2X3] synonym: "DC-SIGN-related protein" EXACT [UniProtKB:Q9H2X3] synonym: "DC-SIGN2" EXACT [UniProtKB:Q9H2X3] synonym: "DC-SIGNR" EXACT [UniProtKB:Q9H2X3] synonym: "Dendritic cell-specific ICAM-3-grabbing non-integrin 2" EXACT [UniProtKB:Q9H2X3] synonym: "L-SIGN" EXACT [UniProtKB:Q9H2X3] synonym: "Liver/lymph node-specific ICAM-3-grabbing non-integrin" EXACT [UniProtKB:Q9H2X3] xref: EMBL:AAG13815.2 xref: EMBL:AAG13848.2 xref: EMBL:AAH38851.1 xref: EMBL:AAK20998.1 xref: EMBL:AAK91859.1 xref: EMBL:AAK91860.1 xref: EMBL:AAK91861.1 xref: EMBL:AAK91862.1 xref: EMBL:AAK91863.1 xref: EMBL:AAK91864.1 xref: EMBL:AAK91865.1 xref: EMBL:AAR04559.1 xref: EMBL:BAA76496.1 xref: EMBL:BAB14667.1 xref: UniProtKB:A6NKI4 xref: UniProtKB:Q69F40 xref: UniProtKB:Q969M4 xref: UniProtKB:Q96QP3 xref: UniProtKB:Q96QP4 xref: UniProtKB:Q96QP5 xref: UniProtKB:Q96QP6 xref: UniProtKB:Q9BXS3 xref: UniProtKB:Q9H2Q9 xref: UniProtKB:Q9H2X3 xref: UniProtKB:Q9H8F0 xref: UniProtKB:Q9Y2A8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017379 ! CLEC4M_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001662 ! mannose binding relationship: has_function CCO:F0004414 ! ICAM-3 receptor activity relationship: has_function CCO:F0005690 ! exogenous peptide antigen binding relationship: has_function CCO:F0006246 ! virion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058692 name: ZF106_HUMAN def: "Zinc finger protein 106 homolog" [UniProtKB:Q9H2Y7] synonym: "Zfp-106" EXACT [UniProtKB:Q9H2Y7] synonym: "Zinc finger protein 474" EXACT [UniProtKB:Q9H2Y7] xref: EMBL:AAG35666.1 xref: EMBL:AAH58023.1 xref: EMBL:AAH70244.1 xref: EMBL:AAL40184.1 xref: EMBL:BAB14976.1 xref: EMBL:BAB71475.1 xref: EMBL:CAD89926.1 xref: EMBL:CAD91134.1 xref: EMBL:CAD91142.1 xref: EMBL:CAD91147.1 xref: EMBL:CAD91149.1 xref: UniProtKB:Q6NSD9 xref: UniProtKB:Q6PEK1 xref: UniProtKB:Q86T43 xref: UniProtKB:Q86T45 xref: UniProtKB:Q86T50 xref: UniProtKB:Q86T58 xref: UniProtKB:Q86TA9 xref: UniProtKB:Q96M37 xref: UniProtKB:Q9H2Y7 xref: UniProtKB:Q9H7B8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020580 ! ZFP106_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0071998 ! ZF106_HUMAN-Phosphoserine859 relationship: transforms_into CCO:B0071999 ! ZF106_HUMAN-Phosphoserine861 relationship: transforms_into CCO:B0072000 ! ZF106_HUMAN-Phosphoserine864 relationship: transforms_into CCO:B0072001 ! ZF106_HUMAN-Phosphoserine937 relationship: transforms_into CCO:B0072002 ! ZF106_HUMAN-Phosphothreonine1021 relationship: transforms_into CCO:B0072003 ! ZF106_HUMAN-Phosphoserine1025 relationship: transforms_into CCO:B0072004 ! ZF106_HUMAN-Phosphoserine1026 relationship: transforms_into CCO:B0072005 ! ZF106_HUMAN-Phosphoserine1031 relationship: transforms_into CCO:B0072006 ! ZF106_HUMAN-Phosphoserine1261 relationship: transforms_into CCO:B0072007 ! ZF106_HUMAN-Phosphoserine1279 relationship: transforms_into CCO:B0072008 ! ZF106_HUMAN-Phosphoserine1281 relationship: transforms_into CCO:B0072009 ! ZF106_HUMAN-Phosphoserine1328 [Term] id: CCO:B0058693 name: LITFL_HUMAN def: "LITAF-like protein" [UniProtKB:Q9H305] synonym: "Cell death-inducing protein" EXACT [UniProtKB:Q9H305] synonym: "Transmembrane protein I1" EXACT [UniProtKB:Q9H305] xref: EMBL:AAF26619.1 xref: EMBL:AAG35583.1 xref: EMBL:AAH02882.1 xref: EMBL:AAH07604.1 xref: EMBL:AAZ94626.1 xref: EMBL:CAB66633.1 xref: EMBL:CAD38712.1 xref: EMBL:CAG38477.1 xref: UniProtKB:Q96ID8 xref: UniProtKB:Q9H0Q4 xref: UniProtKB:Q9H305 xref: UniProtKB:Q9P112 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018503 ! C16orf5_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000839 ! apoptotic program relationship: participates_in CCO:P0001810 ! tumor necrosis factor-mediated signaling pathway relationship: participates_in CCO:P0002126 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis [Term] id: CCO:B0058694 name: O51B5_HUMAN def: "Olfactory receptor 51B5" [UniProtKB:Q9H339] synonym: "Odorant receptor HOR5'beta5" EXACT [UniProtKB:Q9H339] synonym: "Olfactory receptor OR11-37" EXACT [UniProtKB:Q9H339] xref: EMBL:AAG41683.1 xref: EMBL:DAA04828.1 xref: UniProtKB:Q9H339 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018985 ! OR51B5_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058695 name: O51B6_HUMAN def: "Olfactory receptor 51B5" [UniProtKB:Q9H340] synonym: "Odorant receptor HOR5'beta6" EXACT [UniProtKB:Q9H340] xref: EMBL:AAG41682.1 xref: UniProtKB:Q9H340 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018986 ! OR51B6_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058696 name: O51M1_HUMAN def: "Olfactory receptor 51M1" [UniProtKB:Q9H341] synonym: "Odorant receptor HOR5'beta7" EXACT [UniProtKB:Q9H341] synonym: "Olfactory receptor OR11-40" EXACT [UniProtKB:Q9H341] xref: EMBL:AAG41681.1 xref: EMBL:DAA04780.1 xref: UniProtKB:Q6IF80 xref: UniProtKB:Q9H341 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018998 ! OR51M1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058697 name: O51J1_HUMAN def: "Olfactory receptor 51J1" [UniProtKB:Q9H342] synonym: "Odorant receptor HOR5'beta8" EXACT [UniProtKB:Q9H342] xref: EMBL:AAG41680.1 xref: UniProtKB:Q9H342 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018996 ! OR51J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058698 name: O51I1_HUMAN def: "Olfactory receptor 51I1" [UniProtKB:Q9H343] synonym: "Odorant receptor HOR5'beta11" EXACT [UniProtKB:Q9H343] synonym: "Olfactory receptor OR11-39" EXACT [UniProtKB:Q9H343] xref: EMBL:AAG41679.1 xref: EMBL:DAA04827.1 xref: UniProtKB:Q6IF33 xref: UniProtKB:Q9H343 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018994 ! OR51I1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058699 name: O51I2_HUMAN def: "Olfactory receptor 51I2" [UniProtKB:Q9H344] synonym: "Odorant receptor HOR5'beta12" EXACT [UniProtKB:Q9H344] synonym: "Olfactory receptor OR11-38" EXACT [UniProtKB:Q9H344] xref: EMBL:AAG41678.1 xref: EMBL:DAA04779.1 xref: UniProtKB:Q6IF81 xref: UniProtKB:Q9H344 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018995 ! OR51I2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058700 name: Q9H345_HUMAN def: "HOR5'Beta13" [UniProtKB:Q9H345] xref: EMBL:AAG41677.1 xref: UniProtKB:Q9H345 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058701 name: O52D1_HUMAN def: "Olfactory receptor 52D1" [UniProtKB:Q9H346] synonym: "Odorant receptor HOR5'beta14" EXACT [UniProtKB:Q9H346] synonym: "Olfactory receptor OR11-43" EXACT [UniProtKB:Q9H346] xref: EMBL:AAG41676.1 xref: EMBL:DAA04674.1 xref: UniProtKB:Q6IFI6 xref: UniProtKB:Q9H346 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019006 ! OR52D1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058702 name: TCAL2_HUMAN def: "Transcription elongation factor A protein-like 2" [UniProtKB:Q9H3H9] synonym: "TCEA-like protein 2" EXACT [UniProtKB:Q9H3H9] synonym: "Transcription elongation factor S-II protein-like 2" EXACT [UniProtKB:Q9H3H9] xref: EMBL:AAG43164.1 xref: EMBL:AAH93932.1 xref: EMBL:AAI04765.1 xref: EMBL:AAL37355.1 xref: EMBL:CAI42278.1 xref: UniProtKB:Q9H3H9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020201 ! TCEAL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058703 name: Q9H3I5_HUMAN def: "Brain my041 protein" [UniProtKB:Q9H3I5] xref: EMBL:AAG43158.1 xref: UniProtKB:Q9H3I5 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058704 name: Q9H3K3_HUMAN def: "My020 protein" [UniProtKB:Q9H3K3] xref: EMBL:AAG43134.1 xref: UniProtKB:Q9H3K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0058705 name: TXND1_HUMAN def: "Thioredoxin domain-containing protein 1 precursor" [UniProtKB:Q9H3N1] synonym: "Thioredoxin-related transmembrane protein" EXACT [UniProtKB:Q9H3N1] synonym: "Transmembrane Trx-related protein" EXACT [UniProtKB:Q9H3N1] xref: EMBL:AAH36460.1 xref: EMBL:AAH56874.2 xref: EMBL:AAQ89003.1 xref: EMBL:BAB20629.1 xref: EMBL:BAC11593.1 xref: EMBL:CAB45700.2 xref: UniProtKB:Q8N487 xref: UniProtKB:Q8NBN5 xref: UniProtKB:Q9H3N1 xref: UniProtKB:Q9Y4T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020390 ! TXNDC1_human relationship: has_function CCO:F0002533 ! disulfide oxidoreductase activity relationship: has_function CCO:F0004499 ! arsenate reductase (thioredoxin) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071636 ! TXND1_HUMAN-Phosphoserine247 relationship: transforms_into CCO:B0071637 ! TXND1_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0071638 ! TXND1_HUMAN-Phosphoserine280 [Term] id: CCO:B0058706 name: HRH4_HUMAN def: "Histamine H4 receptor" [UniProtKB:Q9H3N8] synonym: "AXOR35" EXACT [UniProtKB:Q9H3N8] synonym: "G-protein coupled receptor 105" EXACT [UniProtKB:Q9H3N8] synonym: "GPRv53" EXACT [UniProtKB:Q9H3N8] synonym: "HH4R" EXACT [UniProtKB:Q9H3N8] synonym: "Pfi-013" EXACT [UniProtKB:Q9H3N8] synonym: "SP9144" EXACT [UniProtKB:Q9H3N8] xref: EMBL:AAG32052.1 xref: EMBL:AAH69136.1 xref: EMBL:AAI12349.1 xref: EMBL:AAK12081.1 xref: EMBL:AAK43542.1 xref: EMBL:AAL01684.1 xref: EMBL:AAN01271.1 xref: EMBL:BAB13698.1 xref: EMBL:BAB20091.1 xref: EMBL:CAC83493.1 xref: UniProtKB:Q4G0I6 xref: UniProtKB:Q9GZQ0 xref: UniProtKB:Q9H3N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018161 ! HRH4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058707 name: NELFA_HUMAN def: "Negative elongation factor A" [UniProtKB:Q9H3P2] synonym: "NELF-A" EXACT [UniProtKB:Q9H3P2] synonym: "Wolf-Hirschhorn syndrome candidate 2 protein" EXACT [UniProtKB:Q9H3P2] xref: EMBL:AAC72982.1 xref: EMBL:AAD20034.1 xref: EMBL:AAH02764.2 xref: EMBL:BAB18651.1 xref: EMBL:BAG54283.1 xref: EMBL:CAM15219.1 xref: EMBL:EAW82546.1 xref: UniProtKB:A2A2T1 xref: UniProtKB:O95392 xref: UniProtKB:Q9H3P2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018749 ! WHSC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068562 ! NELFA_HUMAN-Phosphothreonine157 relationship: transforms_into CCO:B0068563 ! NELFA_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0068564 ! NELFA_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0068565 ! NELFA_HUMAN-Phosphothreonine365 [Term] id: CCO:B0058708 name: BORG4_HUMAN def: "Cdc42 effector protein 4" [UniProtKB:Q9H3Q1] synonym: "Binder of Rho GTPases 4" EXACT [UniProtKB:Q9H3Q1] xref: EMBL:AAD16299.1 xref: EMBL:AAH02774.1 xref: EMBL:AAH10451.1 xref: EMBL:BAB17272.1 xref: UniProtKB:O95828 xref: UniProtKB:Q96FT3 xref: UniProtKB:Q9H3Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017174 ! CDC42EP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015135 ! cdc42ep4-wdr6 physical interaction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0001391 ! positive regulation of pseudopodium formation relationship: transforms_into CCO:B0063955 ! BORG4_HUMAN-Phosphoserine64 relationship: transforms_into CCO:B0063956 ! BORG4_HUMAN-Phosphoserine138 relationship: transforms_into CCO:B0063957 ! BORG4_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0063958 ! BORG4_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0063959 ! BORG4_HUMAN-Phosphoserine292 relationship: transforms_into CCO:B0063960 ! BORG4_HUMAN-Phosphoserine295 [Term] id: CCO:B0058709 name: JHD3C_HUMAN def: "JmjC domain-containing histone demethylation protein 3C" [UniProtKB:Q9H3R0] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q9H3R0] synonym: "GASC-1 protein" EXACT [UniProtKB:Q9H3R0] synonym: "Gene amplified in squamous cell carcinoma 1 protein" EXACT [UniProtKB:Q9H3R0] synonym: "Jumonji domain-containing protein 2C" EXACT [UniProtKB:Q9H3R0] xref: EMBL:AAI04860.1 xref: EMBL:AAI04862.1 xref: EMBL:BAA34500.1 xref: EMBL:BAB16102.1 xref: EMBL:CAH73283.1 xref: EMBL:CAH73284.1 xref: EMBL:CAI16322.1 xref: EMBL:CAI16323.1 xref: EMBL:CAI39531.1 xref: EMBL:CAI39532.1 xref: EMBL:CAI39533.1 xref: EMBL:CAI39606.1 xref: EMBL:CAI39607.1 xref: EMBL:CAI39608.1 xref: UniProtKB:O94877 xref: UniProtKB:Q2M3M0 xref: UniProtKB:Q5JUC9 xref: UniProtKB:Q5VYJ2 xref: UniProtKB:Q5VYJ3 xref: UniProtKB:Q9H3R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018364 ! JMJD2C_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058710 name: Q9H3R7_HUMAN def: "Dickkopf-2 variant" [UniProtKB:Q9H3R7] synonym: "Dickkopf homolog 2 (Xenopus laevis), isoform CRA_a" EXACT [UniProtKB:Q9H3R7] xref: EMBL:BAB20420.1 xref: EMBL:EAX06208.1 xref: UniProtKB:Q9H3R7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017580 ! DKK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0058711 name: MS4A5_HUMAN def: "Membrane-spanning 4-domains subfamily A member 5" [UniProtKB:Q9H3V2] synonym: "CD20 antigen" EXACT [UniProtKB:Q9H3V2] synonym: "CD20 antigen-like 2" EXACT [UniProtKB:Q9H3V2] synonym: "Testis-expressed transmembrane 4 protein" EXACT [UniProtKB:Q9H3V2] xref: EMBL:AAH29884.1 xref: EMBL:AAK01641.1 xref: EMBL:AAK37416.1 xref: EMBL:BAB18739.1 xref: UniProtKB:Q9BZH1 xref: UniProtKB:Q9H3V2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018663 ! MS4A5_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058712 name: OFUT1_HUMAN def: "GDP-fucose protein O-fucosyltransferase 1 precursor" [UniProtKB:Q9H488] synonym: "EC 2.4.1.221" EXACT [UniProtKB:Q9H488] synonym: "O-FucT-1" EXACT [UniProtKB:Q9H488] synonym: "Peptide-O-fucosyltransferase 1" EXACT [UniProtKB:Q9H488] xref: EMBL:AAH00582.1 xref: EMBL:AAL09576.1 xref: EMBL:BAA11497.2 xref: EMBL:CAC16424.1 xref: UniProtKB:Q14685 xref: UniProtKB:Q9BW76 xref: UniProtKB:Q9H488 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019040 ! POFUT1_human relationship: has_function CCO:F0001884 ! fucosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006274 ! peptide-O-fucosyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058713 name: WNK1_HUMAN def: "Serine/threonine-protein kinase WNK1" [UniProtKB:Q9H4A3] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9H4A3] synonym: "Erythrocyte 65 kDa protein" EXACT [UniProtKB:Q9H4A3] synonym: "Kinase deficient protein" EXACT [UniProtKB:Q9H4A3] synonym: "p65" EXACT [UniProtKB:Q9H4A3] synonym: "Protein kinase with no lysine 1" EXACT [UniProtKB:Q9H4A3] synonym: "Protein kinase, lysine-deficient 1" EXACT [UniProtKB:Q9H4A3] xref: EMBL:AAF31483.1 xref: EMBL:AAH21121.1 xref: EMBL:AAO46160.1 xref: EMBL:BAA20802.2 xref: EMBL:CAC15059.1 xref: UniProtKB:O15052 xref: UniProtKB:P54963 xref: UniProtKB:Q86WL5 xref: UniProtKB:Q8N673 xref: UniProtKB:Q9H4A3 xref: UniProtKB:Q9P1S9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020480 ! WNK1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0002955 ! regulation of cellular process relationship: transforms_into CCO:B0071844 ! WNK1_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0071845 ! WNK1_HUMAN-Phosphoserine167 relationship: transforms_into CCO:B0071846 ! WNK1_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0071847 ! WNK1_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0071848 ! WNK1_HUMAN-Phosphoserine382 relationship: transforms_into CCO:B0071849 ! WNK1_HUMAN-Phosphoserine1261 relationship: transforms_into CCO:B0071850 ! WNK1_HUMAN-Phosphoserine1297 relationship: transforms_into CCO:B0071851 ! WNK1_HUMAN-Phosphoserine1300 relationship: transforms_into CCO:B0071852 ! WNK1_HUMAN-Phosphoserine1978 relationship: transforms_into CCO:B0071853 ! WNK1_HUMAN-Phosphoserine2002 relationship: transforms_into CCO:B0071854 ! WNK1_HUMAN-Phosphoserine2011 relationship: transforms_into CCO:B0071855 ! WNK1_HUMAN-Phosphoserine2012 relationship: transforms_into CCO:B0071856 ! WNK1_HUMAN-Phosphoserine2027 relationship: transforms_into CCO:B0071857 ! WNK1_HUMAN-Phosphoserine2029 relationship: transforms_into CCO:B0071858 ! WNK1_HUMAN-Phosphoserine2032 relationship: transforms_into CCO:B0071859 ! WNK1_HUMAN-Phosphoserine2038 relationship: transforms_into CCO:B0071860 ! WNK1_HUMAN-Phosphoserine2121 [Term] id: CCO:B0058714 name: Q9H4A8_HUMAN def: "FUS/ATF-1 protein" [UniProtKB:Q9H4A8] xref: EMBL:CAC15058.1 xref: UniProtKB:Q9H4A8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021263 ! FUS/ATF-1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058715 name: SAV1_HUMAN def: "Protein salvador homolog 1" [UniProtKB:Q9H4B6] synonym: "45 kDa WW domain protein" EXACT [UniProtKB:Q9H4B6] synonym: "hWW45" EXACT [UniProtKB:Q9H4B6] xref: EMBL:AAH20537.1 xref: EMBL:BAB13835.1 xref: EMBL:BAB14390.1 xref: EMBL:CAC13972.1 xref: EMBL:CAG33578.1 xref: UniProtKB:Q6IA58 xref: UniProtKB:Q9H4B6 xref: UniProtKB:Q9H949 xref: UniProtKB:Q9HAK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019841 ! SAV1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015856 ! stk4-sav1-1 physical interaction relationship: participates_in CCO:I0015999 ! stk4-sav1-2 physical interaction relationship: participates_in CCO:I0016000 ! stk3-sav1-1 physical interaction relationship: participates_in CCO:I0016001 ! stk4-sav1-3 physical interaction relationship: participates_in CCO:I0016002 ! stk3-sav1-2 physical interaction relationship: participates_in CCO:I0016003 ! sav1-sav1-1 physical interaction relationship: participates_in CCO:I0018731 ! stk3-sav1-3 phosphorylation relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058716 name: RHOJ_HUMAN def: "Rho-related GTP-binding protein RhoJ precursor" [UniProtKB:Q9H4E5] synonym: "Ras-like protein family member 7B" EXACT [UniProtKB:Q9H4E5] synonym: "Tc10-like GTP-binding protein TCL" EXACT [UniProtKB:Q9H4E5] xref: EMBL:AAH62575.1 xref: EMBL:AAL09440.1 xref: EMBL:AAM21124.1 xref: EMBL:BAB55013.1 xref: EMBL:BAB55055.1 xref: EMBL:CAC06611.1 xref: UniProtKB:Q96KC1 xref: UniProtKB:Q9H4E5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019734 ! RHOJ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0070013 ! RHOJ_HUMAN-Cysteine methyl ester211 [Term] id: CCO:B0058717 name: SMRCD_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1" [UniProtKB:Q9H4L7] synonym: "ATP-dependent helicase 1" EXACT [UniProtKB:Q9H4L7] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9H4L7] synonym: "hHEL1" EXACT [UniProtKB:Q9H4L7] xref: EMBL:AAG16639.1 xref: EMBL:AAH45534.1 xref: EMBL:BAA86436.1 xref: EMBL:BAB14759.1 xref: EMBL:BAB55150.1 xref: EMBL:CAB95769.1 xref: EMBL:CAC21685.1 xref: UniProtKB:Q96SX1 xref: UniProtKB:Q9H017 xref: UniProtKB:Q9H4L7 xref: UniProtKB:Q9H860 xref: UniProtKB:Q9NPU9 xref: UniProtKB:Q9ULU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019953 ! SMARCAD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000398 ! regulation of DNA recombination relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0070650 ! SMRCD_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0070651 ! SMRCD_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0070652 ! SMRCD_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0070653 ! SMRCD_HUMAN-Phosphothreonine54 relationship: transforms_into CCO:B0070654 ! SMRCD_HUMAN-Phosphoserine57 relationship: transforms_into CCO:B0070655 ! SMRCD_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0070656 ! SMRCD_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0070657 ! SMRCD_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0070658 ! SMRCD_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0070659 ! SMRCD_HUMAN-Phosphoserine98 relationship: transforms_into CCO:B0070660 ! SMRCD_HUMAN-Phosphoserine103 relationship: transforms_into CCO:B0070661 ! SMRCD_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0070662 ! SMRCD_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0070663 ! SMRCD_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0070664 ! SMRCD_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0070665 ! SMRCD_HUMAN-Phosphoserine152 relationship: transforms_into CCO:B0070666 ! SMRCD_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0070667 ! SMRCD_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0070668 ! SMRCD_HUMAN-Phosphoserine213 relationship: transforms_into CCO:B0070669 ! SMRCD_HUMAN-Phosphoserine214 relationship: transforms_into CCO:B0070670 ! SMRCD_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0070671 ! SMRCD_HUMAN-Phosphoserine242 relationship: transforms_into CCO:B0070672 ! SMRCD_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0070673 ! SMRCD_HUMAN-Phosphoserine408 [Term] id: CCO:B0058718 name: PRD13_HUMAN def: "PR domain zinc finger protein 13" [UniProtKB:Q9H4Q3] synonym: "PR domain-containing protein 13" EXACT [UniProtKB:Q9H4Q3] xref: EMBL:AAG13448.1 xref: EMBL:CAI19763.1 xref: EMBL:CAI22063.1 xref: UniProtKB:Q5TGC1 xref: UniProtKB:Q9H4Q3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019489 ! PRDM13_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058719 name: PRD12_HUMAN def: "PR domain zinc finger protein 12" [UniProtKB:Q9H4Q4] synonym: "PR domain-containing protein 12" EXACT [UniProtKB:Q9H4Q4] xref: EMBL:AAG13447.2 xref: UniProtKB:Q9H4Q4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019488 ! PRDM12_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058720 name: COE3_HUMAN def: "Transcription factor COE3" [UniProtKB:Q9H4W6] synonym: "Early B-cell factor 3" EXACT [UniProtKB:Q9H4W6] synonym: "EBF-3" EXACT [UniProtKB:Q9H4W6] synonym: "O/E-2" EXACT [UniProtKB:Q9H4W6] synonym: "OE-2" EXACT [UniProtKB:Q9H4W6] synonym: "Olf-1/EBF-like 2" EXACT [UniProtKB:Q9H4W6] xref: EMBL:CAI12792.1 xref: EMBL:CAI12793.1 xref: UniProtKB:Q5T6H9 xref: UniProtKB:Q9H4W5 xref: UniProtKB:Q9H4W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017428 ! EBF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058721 name: ZN335_HUMAN def: "Zinc finger protein 335" [UniProtKB:Q9H4Z2] synonym: "NIF-1" EXACT [UniProtKB:Q9H4Z2] synonym: "NRC-interacting factor 1" EXACT [UniProtKB:Q9H4Z2] xref: EMBL:AAN09900.1 xref: EMBL:BAB15379.1 xref: EMBL:BAG59529.1 xref: EMBL:CAC10457.1 xref: UniProtKB:B4DLG7 xref: UniProtKB:Q548D0 xref: UniProtKB:Q9H4Z2 xref: UniProtKB:Q9H684 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020710 ! ZNF335_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072112 ! ZN335_HUMAN-Phosphoserine416 relationship: transforms_into CCO:B0072113 ! ZN335_HUMAN-Phosphoserine976 relationship: transforms_into CCO:B0072114 ! ZN335_HUMAN-Phosphoserine1153 [Term] id: CCO:B0058722 name: ESF1_HUMAN def: "ESF1 homolog" [UniProtKB:Q9H501] synonym: "ABT1-associated protein" EXACT [UniProtKB:Q9H501] xref: EMBL:AAF65504.1 xref: EMBL:AAH46107.1 xref: EMBL:BAA91123.1 xref: EMBL:BAB14023.1 xref: EMBL:BAB14167.1 xref: EMBL:CAC07199.1 xref: UniProtKB:Q86X92 xref: UniProtKB:Q9H501 xref: UniProtKB:Q9H9Q5 xref: UniProtKB:Q9HA35 xref: UniProtKB:Q9NX93 xref: UniProtKB:Q9P1S6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017728 ! ESF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065141 ! ESF1_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0065142 ! ESF1_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0065143 ! ESF1_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0065144 ! ESF1_HUMAN-Phosphoserine82 relationship: transforms_into CCO:B0065145 ! ESF1_HUMAN-Phosphoserine90 relationship: transforms_into CCO:B0065146 ! ESF1_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0065147 ! ESF1_HUMAN-Phosphoserine179 relationship: transforms_into CCO:B0065148 ! ESF1_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0065149 ! ESF1_HUMAN-Phosphoserine198 relationship: transforms_into CCO:B0065150 ! ESF1_HUMAN-Phosphoserine296 relationship: transforms_into CCO:B0065151 ! ESF1_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0065152 ! ESF1_HUMAN-Phosphothreonine311 relationship: transforms_into CCO:B0065153 ! ESF1_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0065154 ! ESF1_HUMAN-Phosphoserine313 relationship: transforms_into CCO:B0065155 ! ESF1_HUMAN-Phosphoserine657 relationship: transforms_into CCO:B0065156 ! ESF1_HUMAN-Phosphoserine663 relationship: transforms_into CCO:B0065157 ! ESF1_HUMAN-Phosphothreonine693 relationship: transforms_into CCO:B0065158 ! ESF1_HUMAN-Phosphoserine694 relationship: transforms_into CCO:B0065159 ! ESF1_HUMAN-Phosphoserine735 relationship: transforms_into CCO:B0065160 ! ESF1_HUMAN-Phosphoserine823 [Term] id: CCO:B0058723 name: ZN644_HUMAN def: "Zinc finger protein 644" [UniProtKB:Q9H582] synonym: "Zep-2" EXACT [UniProtKB:Q9H582] synonym: "Zinc finger motif enhancer-binding protein 2" EXACT [UniProtKB:Q9H582] xref: EMBL:AAH50656.1 xref: EMBL:AAH63683.2 xref: EMBL:BAA86535.1 xref: EMBL:BAD32777.1 xref: EMBL:CAI23362.1 xref: EMBL:CAI23363.1 xref: UniProtKB:Q5TCC0 xref: UniProtKB:Q6BEP7 xref: UniProtKB:Q6P446 xref: UniProtKB:Q6PI06 xref: UniProtKB:Q7LG67 xref: UniProtKB:Q9H582 xref: UniProtKB:Q9ULJ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020872 ! ZNF644_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072202 ! ZN644_HUMAN-Phosphoserine309 relationship: transforms_into CCO:B0072203 ! ZN644_HUMAN-Phosphoserine1000 relationship: transforms_into CCO:B0072204 ! ZN644_HUMAN-Phosphoserine1189 [Term] id: CCO:B0058724 name: DUS21_HUMAN def: "Dual specificity protein phosphatase 21" [UniProtKB:Q9H596] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9H596] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9H596] synonym: "Low molecular weight dual specificity phosphatase 21" EXACT [UniProtKB:Q9H596] xref: EMBL:AAI19756.1 xref: EMBL:AAI19757.1 xref: EMBL:AAN59788.1 xref: EMBL:AAO17295.1 xref: EMBL:CAC10195.1 xref: EMBL:CAG33440.1 xref: UniProtKB:Q0VDA6 xref: UniProtKB:Q6IAJ6 xref: UniProtKB:Q6YDQ8 xref: UniProtKB:Q9H596 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017634 ! DUSP21_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058725 name: ZN768_HUMAN def: "Zinc finger protein 768" [UniProtKB:Q9H5H4] xref: EMBL:AAH13760.1 xref: EMBL:AAH92403.2 xref: EMBL:BAB15652.1 xref: UniProtKB:Q569L7 xref: UniProtKB:Q96CX4 xref: UniProtKB:Q9H5H4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020928 ! ZNF768_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072232 ! ZN768_HUMAN-Phosphoserine17 relationship: transforms_into CCO:B0072233 ! ZN768_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0072234 ! ZN768_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0072235 ! ZN768_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0072236 ! ZN768_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0072237 ! ZN768_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0072238 ! ZN768_HUMAN-Phosphoserine299 [Term] id: CCO:B0058726 name: Q9H5I4_HUMAN def: "cDNA: FLJ23404 fis, clone HEP18862" [UniProtKB:Q9H5I4] synonym: "Zinc finger protein 33A, isoform CRA_c" EXACT [UniProtKB:Q9H5I4] xref: EMBL:BAB15642.1 xref: EMBL:EAW85890.1 xref: UniProtKB:Q9H5I4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020712 ! ZNF33A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058727 name: ZBTB3_HUMAN def: "Zinc finger and BTB domain-containing protein 3" [UniProtKB:Q9H5J0] xref: EMBL:AAH25249.1 xref: EMBL:BAB15636.1 xref: UniProtKB:Q9H5J0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020568 ! ZBTB3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058728 name: TFB2M_HUMAN def: "Dimethyladenosine transferase 2, mitochondrial precursor" [UniProtKB:Q9H5Q4] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q9H5Q4] synonym: "h-mtTFB" EXACT [UniProtKB:Q9H5Q4] synonym: "h-mtTFB2" EXACT [UniProtKB:Q9H5Q4] synonym: "HCV NS5A-transactivated protein 5" EXACT [UniProtKB:Q9H5Q4] synonym: "Hepatitis C virus NS5A-transactivated protein 5" EXACT [UniProtKB:Q9H5Q4] synonym: "hTFB2M" EXACT [UniProtKB:Q9H5Q4] synonym: "Mitochondrial 12S rRNA dimethylase 2" EXACT [UniProtKB:Q9H5Q4] synonym: "Mitochondrial transcription factor B2" EXACT [UniProtKB:Q9H5Q4] synonym: "mtTFB2" EXACT [UniProtKB:Q9H5Q4] synonym: "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2" EXACT [UniProtKB:Q9H5Q4] xref: EMBL:AAH03383.1 xref: EMBL:AAQ09600.1 xref: EMBL:BAB15441.1 xref: EMBL:BAB15566.1 xref: EMBL:CAI16399.1 xref: UniProtKB:Q9H5Q4 xref: UniProtKB:Q9H626 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020247 ! TFB2M_human relationship: has_function CCO:F0000035 ! rRNA (adenine-N6,N6-)-dimethyltransferase activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0002014 ! rRNA methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058729 name: IKZF5_HUMAN def: "Zinc finger protein Pegasus" [UniProtKB:Q9H5V7] synonym: "Ikaros family zinc finger protein 5" EXACT [UniProtKB:Q9H5V7] xref: EMBL:AAG39220.1 xref: EMBL:BAB15512.1 xref: EMBL:CAH18660.1 xref: EMBL:CAH56199.1 xref: EMBL:EAW49292.1 xref: UniProtKB:Q9H2T0 xref: UniProtKB:Q9H5V7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018246 ! IKZF5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058730 name: ZN576_HUMAN def: "Zinc finger protein 576" [UniProtKB:Q9H609] xref: EMBL:AAH02981.1 xref: EMBL:BAB15458.1 xref: UniProtKB:Q9BU03 xref: UniProtKB:Q9H609 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020833 ! ZNF576_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072159 ! ZN576_HUMAN-Phosphothreonine120 relationship: transforms_into CCO:B0072160 ! ZN576_HUMAN-Phosphoserine126 [Term] id: CCO:B0058731 name: PIF1_HUMAN def: "ATP-dependent DNA helicase PIF1" [UniProtKB:Q9H611] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9H611] synonym: "PIF1/RRM3 DNA helicase-like protein" EXACT [UniProtKB:Q9H611] xref: EMBL:AAS77398.1 xref: EMBL:ABD92708.1 xref: EMBL:BAB15456.1 xref: EMBL:BAE47454.1 xref: EMBL:BAE47455.1 xref: UniProtKB:Q1W5B6 xref: UniProtKB:Q330H5 xref: UniProtKB:Q33E24 xref: UniProtKB:Q9H611 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019399 ! PIF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001546 ! regulation of telomere maintenance relationship: transforms_into CCO:B0069308 ! PIF1_HUMAN-Phosphoserine151 [Term] id: CCO:B0058732 name: RERGL_HUMAN def: "Ras-related and estrogen-regulated growth inhibitor-like protein" [UniProtKB:Q9H628] synonym: "RERG/Ras-like protein" EXACT [UniProtKB:Q9H628] xref: EMBL:AAH42888.1 xref: EMBL:BAB15439.1 xref: EMBL:EAW96385.1 xref: UniProtKB:Q9H628 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019675 ! RERGL_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058733 name: Q9H661_HUMAN def: "CDNA: FLJ22582 fis, clone HSI02576 (BAI1-associated protein 2-like 2, isoform CRA_b)" [UniProtKB:Q9H661] xref: EMBL:BAB15405.1 xref: EMBL:EAW60217.1 xref: UniProtKB:Q9H661 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017153 ! BAIAP2L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058734 name: ASB7_HUMAN def: "Ankyrin repeat and SOCS box protein 7" [UniProtKB:Q9H672] synonym: "ASB-7" EXACT [UniProtKB:Q9H672] xref: EMBL:AAP97683.1 xref: EMBL:BAB15392.1 xref: UniProtKB:Q7Z4S3 xref: UniProtKB:Q9H672 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017071 ! ASB7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058735 name: Q9H6M4_HUMAN def: "cDNA: FLJ22098 fis, clone HEP17040" [UniProtKB:Q9H6M4] xref: EMBL:BAB15232.1 xref: UniProtKB:Q9H6M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058736 name: NO66_HUMAN def: "Nucleolar protein 66" [UniProtKB:Q9H6W3] synonym: "hsNO66" EXACT [UniProtKB:Q9H6W3] xref: EMBL:AAH11350.1 xref: EMBL:AAH71954.1 xref: EMBL:AAR27292.1 xref: EMBL:BAB15138.1 xref: UniProtKB:Q9H6W3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018813 ! NO66_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068757 ! NO66_HUMAN-Phosphoserine109 [Term] id: CCO:B0058737 name: ZN552_HUMAN def: "Zinc finger protein 552" [UniProtKB:Q9H707] xref: EMBL:AAH46237.1 xref: EMBL:AAH62982.1 xref: EMBL:AAH82767.1 xref: EMBL:BAB15093.1 xref: UniProtKB:Q6P5A6 xref: UniProtKB:Q9H707 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020812 ! ZNF552_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058738 name: ASB8_HUMAN def: "Ankyrin repeat and SOCS box protein 8" [UniProtKB:Q9H765] synonym: "ASB-8" EXACT [UniProtKB:Q9H765] xref: EMBL:AAH01321.1 xref: EMBL:AAQ04830.1 xref: EMBL:BAB15033.1 xref: UniProtKB:Q547Q2 xref: UniProtKB:Q9H765 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017072 ! ASB8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058739 name: GREM2_HUMAN def: "Gremlin-2 precursor" [UniProtKB:Q9H772] synonym: "Cysteine knot superfamily 1, BMP antagonist 2" EXACT [UniProtKB:Q9H772] synonym: "DAN domain family member 3" EXACT [UniProtKB:Q9H772] synonym: "Protein related to DAN and cerberus" EXACT [UniProtKB:Q9H772] xref: EMBL:AAH46632.1 xref: EMBL:BAB15026.1 xref: EMBL:CAH74074.1 xref: UniProtKB:Q86UD9 xref: UniProtKB:Q9H772 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018056 ! GREM2_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:B0058740 name: Q9H7I9_HUMAN def: "FLJ00094 protein" [UniProtKB:Q9H7I9] xref: EMBL:BAB15781.1 xref: UniProtKB:Q9H7I9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021265 ! FLJ00094_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058741 name: Q9H7M0_HUMAN def: "FLJ00050 protein" [UniProtKB:Q9H7M0] xref: EMBL:BAB15748.1 xref: UniProtKB:Q9H7M0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021266 ! FLJ00050_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0058742 name: PKHG2_HUMAN def: "Pleckstrin homology domain-containing family G member 2" [UniProtKB:Q9H7P9] xref: EMBL:AAH13426.1 xref: EMBL:AAH15174.1 xref: EMBL:AAH75858.1 xref: EMBL:BAB15364.1 xref: EMBL:BAB15719.1 xref: UniProtKB:Q6DHV6 xref: UniProtKB:Q96BU2 xref: UniProtKB:Q96D18 xref: UniProtKB:Q9H699 xref: UniProtKB:Q9H7P9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019414 ! PLEKHG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0069344 ! PKHG2_HUMAN-Phosphothreonine445 relationship: transforms_into CCO:B0069345 ! PKHG2_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0069346 ! PKHG2_HUMAN-Phosphoserine610 [Term] id: CCO:B0058743 name: Q9H7Q2_HUMAN def: "FLJ00015 protein" [UniProtKB:Q9H7Q2] xref: EMBL:BAB15716.1 xref: UniProtKB:Q9H7Q2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021267 ! FLJ00015_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058744 name: ZN442_HUMAN def: "Zinc finger protein 442" [UniProtKB:Q9H7R0] xref: EMBL:BAB14916.1 xref: UniProtKB:Q9H7R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020754 ! ZNF442_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058745 name: ZN665_HUMAN def: "Zinc finger protein 665" [UniProtKB:Q9H7R5] synonym: "Zinc finger protein 160-like" EXACT [UniProtKB:Q9H7R5] xref: EMBL:BAB14911.1 xref: EMBL:BAF84092.1 xref: UniProtKB:A8K5T8 xref: UniProtKB:Q9H7R5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020883 ! ZNF665_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072210 ! ZN665_HUMAN-Phosphotyrosine97 relationship: transforms_into CCO:B0072211 ! ZN665_HUMAN-Phosphotyrosine99 [Term] id: CCO:B0058746 name: ZN703_HUMAN def: "Zinc finger protein 703" [UniProtKB:Q9H7S9] xref: EMBL:AAH32534.1 xref: EMBL:AAH84581.1 xref: EMBL:BAB14897.1 xref: UniProtKB:Q5XG76 xref: UniProtKB:Q9H7S9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020909 ! ZNF703_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058747 name: ZN696_HUMAN def: "Zinc finger protein 696" [UniProtKB:Q9H7X3] xref: EMBL:AAI26318.1 xref: EMBL:BAB14850.1 xref: EMBL:EAW82267.1 xref: UniProtKB:A0AVE2 xref: UniProtKB:Q9H7X3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020903 ! ZNF696_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058748 name: MYST1_HUMAN def: "Probable histone acetyltransferase MYST1" [UniProtKB:Q9H7Z6] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q9H7Z6] synonym: "hMOF" EXACT [UniProtKB:Q9H7Z6] synonym: "MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1" EXACT [UniProtKB:Q9H7Z6] synonym: "MYST protein 1" EXACT [UniProtKB:Q9H7Z6] xref: EMBL:AAF72665.2 xref: EMBL:AAH37773.1 xref: EMBL:AAL55762.1 xref: EMBL:AAL56648.1 xref: EMBL:BAB13924.1 xref: EMBL:BAB14827.1 xref: EMBL:CAH56416.1 xref: UniProtKB:Q659G0 xref: UniProtKB:Q7LC17 xref: UniProtKB:Q8IY59 xref: UniProtKB:Q8WYB4 xref: UniProtKB:Q8WZ14 xref: UniProtKB:Q9H7Z6 xref: UniProtKB:Q9HAC5 xref: UniProtKB:Q9NR35 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018704 ! MYST1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018691 ! err1-trrap-1 physical interaction relationship: participates_in CCO:I0018692 ! err1-trrap-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0068423 ! MYST1_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0068424 ! MYST1_HUMAN-Phosphoserine42 [Term] id: CCO:B0058749 name: Q9H806_HUMAN def: "cDNA FLJ14015 fis, clone HEMBA1000327" [UniProtKB:Q9H806] xref: EMBL:BAB14817.1 xref: UniProtKB:Q9H806 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000269 ! nuclear origin of replication recognition complex relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058750 name: ZN395_HUMAN def: "Zinc finger protein 395" [UniProtKB:Q9H8N7] synonym: "HD gene regulatory region-binding protein 2" EXACT [UniProtKB:Q9H8N7] synonym: "HD-regulating factor 2" EXACT [UniProtKB:Q9H8N7] synonym: "HDBP-2" EXACT [UniProtKB:Q9H8N7] synonym: "HDRF-2" EXACT [UniProtKB:Q9H8N7] synonym: "Huntington disease gene regulatory region-binding protein 2" EXACT [UniProtKB:Q9H8N7] synonym: "Papillomavirus regulatory factor 1" EXACT [UniProtKB:Q9H8N7] synonym: "Papillomavirus-binding factor" EXACT [UniProtKB:Q9H8N7] synonym: "PRF-1" EXACT [UniProtKB:Q9H8N7] xref: EMBL:AAF73463.1 xref: EMBL:AAH01237.1 xref: EMBL:BAA92056.1 xref: EMBL:BAA96783.1 xref: EMBL:BAA96784.1 xref: EMBL:BAA96785.1 xref: EMBL:BAB14571.1 xref: EMBL:BAB39851.1 xref: EMBL:BAD29734.1 xref: UniProtKB:Q6F6H2 xref: UniProtKB:Q9BY72 xref: UniProtKB:Q9H8N7 xref: UniProtKB:Q9NPB2 xref: UniProtKB:Q9NS57 xref: UniProtKB:Q9NS58 xref: UniProtKB:Q9NS59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020728 ! ZNF395_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058751 name: Q9H8R0_HUMAN def: "cDNA FLJ13308 fis, clone OVARC1001436, weakly similar to ENL PROTEIN" [UniProtKB:Q9H8R0] xref: EMBL:BAB14546.1 xref: UniProtKB:Q9H8R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058752 name: Q9H942_HUMAN def: "cDNA FLJ13032 fis, clone NT2RP3001120, moderately similar to ZINC FINGER PROTEIN 136" [UniProtKB:Q9H942] xref: EMBL:BAB14401.1 xref: UniProtKB:Q9H942 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058753 name: ZN702_HUMAN def: "Zinc finger protein 702" [UniProtKB:Q9H963] xref: EMBL:AAH32590.1 xref: EMBL:BAB14373.1 xref: EMBL:BAG52576.1 xref: UniProtKB:Q05BW1 xref: UniProtKB:Q9H963 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020908 ! ZNF702_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058754 name: ZN408_HUMAN def: "Zinc finger protein 408" [UniProtKB:Q9H9D4] synonym: "PR domain zinc finger protein 17" EXACT [UniProtKB:Q9H9D4] xref: EMBL:AAH13355.1 xref: EMBL:AAH15708.1 xref: EMBL:AAK29075.1 xref: EMBL:BAB14295.1 xref: UniProtKB:Q9H9D4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020734 ! ZNF408_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015029 ! khdrbs3-znf408 physical interaction relationship: participates_in CCO:I0015151 ! ldoc1-znf408 physical interaction relationship: participates_in CCO:I0015382 ! thap1-znf408 physical interaction relationship: participates_in CCO:I0015456 ! mdfi-znf408 physical interaction relationship: participates_in CCO:I0015499 ! cep70-znf408 physical interaction relationship: participates_in CCO:I0015633 ! krtap4_12-znf408 physical interaction relationship: participates_in CCO:I0015678 ! ndp52-znf408 physical interaction relationship: participates_in CCO:I0015764 ! q96br9-znf408 physical interaction relationship: participates_in CCO:I0015889 ! rrp4-znf408-1 physical interaction relationship: participates_in CCO:I0015890 ! lsm2-znf408-2 physical interaction relationship: participates_in CCO:I0015895 ! znf408-znf408-1 physical interaction relationship: participates_in CCO:I0015896 ! znf408-rrp4 physical interaction relationship: participates_in CCO:I0017316 ! rrp4-znf408 physical interaction relationship: participates_in CCO:I0017320 ! lsm2-znf408-1 physical interaction relationship: participates_in CCO:I0017337 ! znf408-rgs19ip1 physical interaction relationship: participates_in CCO:I0017338 ! znf408-pdlim4 physical interaction relationship: participates_in CCO:I0017339 ! znf408-ddx56 physical interaction relationship: participates_in CCO:I0017340 ! znf408-lsm2 physical interaction relationship: participates_in CCO:I0017341 ! znf408-znf408 physical interaction relationship: participates_in CCO:I0017342 ! znf408-noa36 physical interaction relationship: participates_in CCO:I0017343 ! znf408-kiaa1793 physical interaction relationship: participates_in CCO:I0017344 ! znf408-mif physical interaction relationship: participates_in CCO:I0017345 ! znf408-top3b physical interaction relationship: participates_in CCO:I0018450 ! lsm2-znf408 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058755 name: MA6D1_HUMAN def: "MAP6 domain-containing protein 1" [UniProtKB:Q9H9H5] synonym: "21 kDa STOP-like protein" EXACT [UniProtKB:Q9H9H5] synonym: "SL21" EXACT [UniProtKB:Q9H9H5] xref: EMBL:AAH06434.1 xref: EMBL:BAB14254.1 xref: UniProtKB:Q9H9H5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018553 ! MAP6D1_human relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000379 ! Golgi-associated vesicle relationship: located_in CCO:C0000380 ! cis-Golgi network relationship: participates_in CCO:P0000693 ! negative regulation of microtubule depolymerization [Term] id: CCO:B0058756 name: NANOG_HUMAN def: "Homeobox protein NANOG" [UniProtKB:Q9H9S0] synonym: "hNanog" EXACT [UniProtKB:Q9H9S0] synonym: "Homeobox transcription factor Nanog" EXACT [UniProtKB:Q9H9S0] xref: EMBL:AAP49529.1 xref: EMBL:AAT81526.1 xref: EMBL:BAB14151.1 xref: EMBL:BAC76999.1 xref: UniProtKB:Q2TTG0 xref: UniProtKB:Q6JZS5 xref: UniProtKB:Q9H9S0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018718 ! NANOG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:B0058757 name: ELP3_HUMAN def: "Elongator complex protein 3" [UniProtKB:Q9H9T3] synonym: "EC 2.3.1.48" EXACT [UniProtKB:Q9H9T3] synonym: "hELP3" EXACT [UniProtKB:Q9H9T3] xref: EMBL:AAH01240.1 xref: EMBL:BAA91600.1 xref: EMBL:BAB14138.1 xref: EMBL:BAD96767.1 xref: EMBL:CAD38948.1 xref: EMBL:CAH10573.1 xref: UniProtKB:Q53G84 xref: UniProtKB:Q6AWB0 xref: UniProtKB:Q9BVF7 xref: UniProtKB:Q9H9T3 xref: UniProtKB:Q9NVZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017697 ! ELP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0065043 ! ELP3_HUMAN-Phosphotyrosine202 [Term] id: CCO:B0058758 name: LN28A_HUMAN def: "Lin-28 homolog A" [UniProtKB:Q9H9Z2] synonym: "Zinc finger CCHC domain-containing protein 1" EXACT [UniProtKB:Q9H9Z2] xref: EMBL:AAH28566.1 xref: EMBL:AAM77751.1 xref: EMBL:BAB14075.1 xref: EMBL:CAI21500.1 xref: UniProtKB:Q9H9Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018513 ! LIN28_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058759 name: ZMAT3_HUMAN def: "Zinc finger matrin-type protein 3" [UniProtKB:Q9HA38] synonym: "p53-activated gene 608 protein" EXACT [UniProtKB:Q9HA38] synonym: "Zinc finger protein WIG-1" EXACT [UniProtKB:Q9HA38] xref: EMBL:AAH02896.1 xref: EMBL:AAK71491.1 xref: EMBL:AAK83287.1 xref: EMBL:BAB14020.1 xref: EMBL:EAW78424.1 xref: EMBL:EAW78426.1 xref: UniProtKB:Q96A21 xref: UniProtKB:Q9HA38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020613 ! ZMAT3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0058760 name: Q9HAG2_HUMAN def: "cDNA FLJ11699 fis, clone HEMBA1005047, highly similar to RAS-RELATED PROTEIN RAB-24" [UniProtKB:Q9HAG2] synonym: "RAB24, member RAS oncogene family, isoform CRA_c" EXACT [UniProtKB:Q9HAG2] xref: EMBL:BAB13887.1 xref: EMBL:EAW85026.1 xref: UniProtKB:Q9HAG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019581 ! RAB24_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058761 name: ZN556_HUMAN def: "Zinc finger protein 556" [UniProtKB:Q9HAH1] xref: EMBL:AAH09374.1 xref: EMBL:BAB13878.1 xref: UniProtKB:Q96GM3 xref: UniProtKB:Q9HAH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020815 ! ZNF556_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058762 name: Q9HAJ3_HUMAN def: "cDNA FLJ11538 fis, clone HEMBA1002746, weakly similar to DNA POLYMERASE BETA (EC 2.7.7.7)" [UniProtKB:Q9HAJ3] synonym: "Polymerase (DNA directed), lambda" EXACT [UniProtKB:Q9HAJ3] xref: EMBL:BAB13852.1 xref: EMBL:CAI41031.1 xref: UniProtKB:Q9HAJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017609 ! POLL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058763 name: SP30L_HUMAN def: "Histone deacetylase complex subunit SAP30L" [UniProtKB:Q9HAJ7] synonym: "HCV non-structural protein 4A-transactivated protein 2" EXACT [UniProtKB:Q9HAJ7] synonym: "Sin3 corepressor complex subunit SAP30L" EXACT [UniProtKB:Q9HAJ7] synonym: "Sin3A-associated protein p30-like protein" EXACT [UniProtKB:Q9HAJ7] xref: EMBL:AAH09829.1 xref: EMBL:AAQ16562.1 xref: EMBL:AAX54477.1 xref: EMBL:BAB13848.1 xref: EMBL:EAW61637.1 xref: UniProtKB:Q9HAJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020001 ! SAP30L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070778 ! SP30L_HUMAN-Phosphothreonine92 relationship: transforms_into CCO:B0070779 ! SP30L_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0070780 ! SP30L_HUMAN-Phosphoserine99 [Term] id: CCO:B0058764 name: COE2_HUMAN def: "Transcription factor COE2" [UniProtKB:Q9HAK2] synonym: "Early B-cell factor 2" EXACT [UniProtKB:Q9HAK2] synonym: "EBF-2" EXACT [UniProtKB:Q9HAK2] xref: EMBL:AAH69665.1 xref: EMBL:AAH69726.1 xref: EMBL:AAH69747.1 xref: EMBL:AAH69768.1 xref: EMBL:AAH74794.2 xref: EMBL:AAI13479.1 xref: EMBL:AAI13505.1 xref: EMBL:BAB13843.1 xref: UniProtKB:A0PJM4 xref: UniProtKB:A6NMF7 xref: UniProtKB:Q6DK36 xref: UniProtKB:Q6IS86 xref: UniProtKB:Q6ISA4 xref: UniProtKB:Q9HAK2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017427 ! EBF2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058765 name: MLXIP_HUMAN def: "MLX-interacting protein" [UniProtKB:Q9HAP2] synonym: "Transcriptional activator MondoA" EXACT [UniProtKB:Q9HAP2] xref: EMBL:AAG34121.1 xref: EMBL:AAH17656.1 xref: EMBL:AAH28309.1 xref: EMBL:AAH39704.1 xref: EMBL:AAL55689.1 xref: EMBL:AAL55690.1 xref: EMBL:BAA74890.2 xref: UniProtKB:O94945 xref: UniProtKB:Q7LC47 xref: UniProtKB:Q8IXP1 xref: UniProtKB:Q8TAH9 xref: UniProtKB:Q8WVQ0 xref: UniProtKB:Q8WYA5 xref: UniProtKB:Q9HAP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018637 ! MLXIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068239 ! MLXIP_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0068240 ! MLXIP_HUMAN-Phosphoserine33 [Term] id: CCO:B0058766 name: LPHN3_HUMAN def: "Latrophilin-3 precursor" [UniProtKB:Q9HAR2] synonym: "Calcium-independent alpha-latrotoxin receptor 3" EXACT [UniProtKB:Q9HAR2] synonym: "Lectomedin-3" EXACT [UniProtKB:Q9HAR2] xref: EMBL:AAG27462.1 xref: EMBL:BAA34488.1 xref: EMBL:BAA91375.1 xref: UniProtKB:O94867 xref: UniProtKB:Q9HAR2 xref: UniProtKB:Q9NWK5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018518 ! LPHN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0067769 ! LPHN3_HUMAN-Phosphothreonine610 relationship: transforms_into CCO:B0067770 ! LPHN3_HUMAN-Phosphothreonine1445 [Term] id: CCO:B0058767 name: ROP1A_HUMAN def: "Ropporin-1A" [UniProtKB:Q9HAT0] synonym: "Cancer/testis antigen 91" EXACT [UniProtKB:Q9HAT0] synonym: "CT91" EXACT [UniProtKB:Q9HAT0] synonym: "Rhophilin-associated protein 1A" EXACT [UniProtKB:Q9HAT0] xref: EMBL:AAG27712.2 xref: EMBL:AAI32745.1 xref: EMBL:AAI32747.1 xref: EMBL:CAB63750.2 xref: UniProtKB:Q9HAT0 xref: UniProtKB:Q9UF38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019768 ! ROPN1_human relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058768 name: SMUF2_HUMAN def: "E3 ubiquitin-protein ligase SMURF2" [UniProtKB:Q9HAU4] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9HAU4] synonym: "hSMURF2" EXACT [UniProtKB:Q9HAU4] synonym: "Smad ubiquitination regulatory factor 2" EXACT [UniProtKB:Q9HAU4] synonym: "Smad-specific E3 ubiquitin ligase 2" EXACT [UniProtKB:Q9HAU4] xref: EMBL:AAG25641.1 xref: EMBL:AAG45422.1 xref: EMBL:AAG50421.1 xref: EMBL:AAH93876.1 xref: EMBL:AAI11946.1 xref: UniProtKB:Q52LL1 xref: UniProtKB:Q9H260 xref: UniProtKB:Q9HAU4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019957 ! SMURF2_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016029 ! rn11-amsh-3 physical interaction relationship: participates_in CCO:I0016030 ! rn11-suf2-1 physical interaction relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: participates_in CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:B0058769 name: GBB4_HUMAN def: "Guanine nucleotide-binding protein subunit beta-4" [UniProtKB:Q9HAV0] synonym: "Transducin beta chain 4" EXACT [UniProtKB:Q9HAV0] xref: EMBL:AAG18442.1 xref: EMBL:AAH00873.1 xref: UniProtKB:Q9HAV0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017879 ! GNB4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066392 ! GBB4_HUMAN-N-acetylserine2 [Term] id: CCO:B0058770 name: TNR27_HUMAN def: "Tumor necrosis factor receptor superfamily member 27" [UniProtKB:Q9HAV5] synonym: "EDA-A2 receptor" EXACT [UniProtKB:Q9HAV5] synonym: "X-linked ectodysplasin-A2 receptor" EXACT [UniProtKB:Q9HAV5] xref: EMBL:AAG28761.1 xref: EMBL:AAH34919.1 xref: EMBL:AAN73210.1 xref: EMBL:AAQ89952.1 xref: EMBL:AAQ89953.1 xref: EMBL:CAH70433.1 xref: EMBL:CAH70434.1 xref: UniProtKB:Q5VYX9 xref: UniProtKB:Q5VYY0 xref: UniProtKB:Q6UWM2 xref: UniProtKB:Q8IZA6 xref: UniProtKB:Q9HAV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020318 ! EDA2R_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001358 ! tumor necrosis factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018792 ! xedar-traf6 physical interaction relationship: participates_in CCO:I0018793 ! xedar-traf3 physical interaction relationship: participates_in CCO:I0018794 ! xedar-fadd physical interaction relationship: participates_in CCO:P0002691 ! positive regulation of JNK cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0058771 name: BRF2_HUMAN def: "Transcription factor IIIB 50 kDa subunit" [UniProtKB:Q9HAW0] synonym: "B-related factor 2" EXACT [UniProtKB:Q9HAW0] synonym: "BRF-2" EXACT [UniProtKB:Q9HAW0] synonym: "hBRFU" EXACT [UniProtKB:Q9HAW0] synonym: "hTFIIIB50" EXACT [UniProtKB:Q9HAW0] synonym: "TFIIIB50" EXACT [UniProtKB:Q9HAW0] xref: EMBL:AAG30222.1 xref: EMBL:AAG35486.1 xref: EMBL:AAG35669.2 xref: EMBL:AAH10648.1 xref: EMBL:BAA91975.1 xref: EMBL:EAW63351.1 xref: UniProtKB:Q9H2Y3 xref: UniProtKB:Q9H3B3 xref: UniProtKB:Q9HAW0 xref: UniProtKB:Q9NUY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017180 ! BRF2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058772 name: PRD16_HUMAN def: "PR domain zinc finger protein 16" [UniProtKB:Q9HAZ2] synonym: "PR domain-containing protein 16" EXACT [UniProtKB:Q9HAZ2] synonym: "Transcription factor MEL1" EXACT [UniProtKB:Q9HAZ2] xref: EMBL:AAG33382.1 xref: EMBL:BAB21766.2 xref: EMBL:BAB84297.1 xref: EMBL:CAH71134.1 xref: EMBL:CAH71530.1 xref: EMBL:CAI19629.1 xref: EMBL:CAI22790.1 xref: UniProtKB:B1AJP9 xref: UniProtKB:Q8WYJ9 xref: UniProtKB:Q9C0I8 xref: UniProtKB:Q9HAZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019492 ! PRDM16_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058773 name: ILRL2_HUMAN def: "Interleukin-1 receptor-like 2 precursor" [UniProtKB:Q9HB29] synonym: "IL-1Rrp2" EXACT [UniProtKB:Q9HB29] synonym: "IL1R-rp2" EXACT [UniProtKB:Q9HB29] synonym: "Interleukin-1 receptor-related protein 2" EXACT [UniProtKB:Q9HB29] xref: EMBL:AAB53237.1 xref: EMBL:AAG21368.1 xref: EMBL:AAX81989.1 xref: EMBL:AAY15046.1 xref: EMBL:AAZ38712.1 xref: UniProtKB:Q13525 xref: UniProtKB:Q45H74 xref: UniProtKB:Q53TU8 xref: UniProtKB:Q587I8 xref: UniProtKB:Q9HB29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018276 ! IL1RL2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_function CCO:F0001256 ! interleukin-1, Type I, activating receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058774 name: SEBOX_HUMAN def: "Homeobox protein SEBOX" [UniProtKB:Q9HB31] synonym: "Homeobox OG-9" EXACT [UniProtKB:Q9HB31] synonym: "Skin-, embryo-, brain- and oocyte-specific homeobox" EXACT [UniProtKB:Q9HB31] xref: EMBL:AAG14458.1 xref: EMBL:EAW51081.1 xref: UniProtKB:Q9HB31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019861 ! SEBOX_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058775 name: Q9HB42_HUMAN def: "GHRH receptor splice variant 4" [UniProtKB:Q9HB42] synonym: "Growth hormone releasing hormone receptor, isoform CRA_c" EXACT [UniProtKB:Q9HB42] xref: EMBL:AAG15371.1 xref: EMBL:EAW93975.1 xref: UniProtKB:Q9HB42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017920 ! GHRHR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003195 ! growth hormone-releasing hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058776 name: Q9HB44_HUMAN def: "GHRH receptor splice variant 2" [UniProtKB:Q9HB44] xref: EMBL:AAG15369.1 xref: UniProtKB:Q9HB44 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003195 ! growth hormone-releasing hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058777 name: SP110_HUMAN def: "Sp110 nuclear body protein" [UniProtKB:Q9HB58] synonym: "Interferon-induced protein 41/75" EXACT [UniProtKB:Q9HB58] synonym: "Speckled 110 kDa" EXACT [UniProtKB:Q9HB58] synonym: "Transcriptional coactivator Sp110" EXACT [UniProtKB:Q9HB58] xref: EMBL:AAA18806.1 xref: EMBL:AAD13402.1 xref: EMBL:AAF99318.1 xref: EMBL:AAG09826.1 xref: EMBL:AAH19059.1 xref: EMBL:AAX93281.1 xref: EMBL:EAW70915.1 xref: UniProtKB:Q14976 xref: UniProtKB:Q14977 xref: UniProtKB:Q53TG2 xref: UniProtKB:Q8WUZ6 xref: UniProtKB:Q9HB58 xref: UniProtKB:Q9HCT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019997 ! SP110_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001376 ! hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020383 ! ndufv2-sp110 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058778 name: ELL3_HUMAN def: "RNA polymerase II elongation factor ELL3" [UniProtKB:Q9HB65] xref: EMBL:AAG13463.1 xref: EMBL:AAH06548.1 xref: EMBL:AAH19293.1 xref: EMBL:BAB15432.1 xref: UniProtKB:Q9H634 xref: UniProtKB:Q9HB65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017689 ! ELL3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001753 ! positive transcription elongation factor activity relationship: has_function CCO:F0003481 ! RNA polymerase II transcription elongation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: participates_in CCO:I0019985 ! ell3-fth1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002565 ! positive regulation of transcription from RNA polymerase II promoter, global [Term] id: CCO:B0058779 name: PIDD_HUMAN def: "Leucine-rich repeat and death domain-containing protein" [UniProtKB:Q9HB75] synonym: "p53-induced protein with a death domain" EXACT [UniProtKB:Q9HB75] xref: EMBL:AAF69491.1 xref: EMBL:AAG13461.1 xref: EMBL:AAH14904.1 xref: EMBL:AAP97716.1 xref: EMBL:BAC11272.1 xref: EMBL:BAD92069.1 xref: EMBL:BAD92186.1 xref: EMBL:BAD92766.1 xref: EMBL:CAD38708.1 xref: UniProtKB:Q59FD1 xref: UniProtKB:Q59H10 xref: UniProtKB:Q59HC7 xref: UniProtKB:Q7Z4P8 xref: UniProtKB:Q8NC89 xref: UniProtKB:Q8NDL2 xref: UniProtKB:Q96C25 xref: UniProtKB:Q9HB75 xref: UniProtKB:Q9NRE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019398 ! LRDD_human relationship: has_function CCO:F0001425 ! death receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016258 ! casp2-cradd-4 physical interaction relationship: participates_in CCO:I0017776 ! casp2-raidd-pidd physical interaction relationship: participates_in CCO:I0017777 ! casp2-raidd-pidd-1 physical interaction relationship: participates_in CCO:I0018022 ! lrdd-cradd-1 physical interaction relationship: participates_in CCO:I0018023 ! casp2-cradd-3 physical interaction relationship: participates_in CCO:I0018024 ! casp2-cradd-5 physical interaction relationship: participates_in CCO:I0018105 ! casp2-pidd-3 colocalization relationship: participates_in CCO:I0018106 ! raidd-pidd-4 colocalization relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058780 name: NMUR1_HUMAN def: "Neuromedin-U receptor 1" [UniProtKB:Q9HB89] synonym: "G-protein coupled receptor 66" EXACT [UniProtKB:Q9HB89] synonym: "G-protein coupled receptor FM-3" EXACT [UniProtKB:Q9HB89] synonym: "NMU-R1" EXACT [UniProtKB:Q9HB89] xref: EMBL:AAC02680.1 xref: EMBL:AAG24793.1 xref: EMBL:AAH36543.1 xref: EMBL:AAH51914.1 xref: EMBL:AAY24249.1 xref: UniProtKB:O43664 xref: UniProtKB:Q7LDP6 xref: UniProtKB:Q8NE20 xref: UniProtKB:Q9HB89 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018810 ! NMUR1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000162 ! neuromedin U receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000739 ! activation of phospholipase C activity relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002762 ! inositol phosphate-mediated signaling [Term] id: CCO:B0058781 name: RRAGC_HUMAN def: "Ras-related GTP-binding protein C" [UniProtKB:Q9HB90] synonym: "GTPase-interacting protein 2" EXACT [UniProtKB:Q9HB90] synonym: "Rag C" EXACT [UniProtKB:Q9HB90] synonym: "TIB929" EXACT [UniProtKB:Q9HB90] xref: EMBL:AAG32662.1 xref: EMBL:AAG45221.1 xref: EMBL:AAH16668.1 xref: EMBL:BAB14548.1 xref: EMBL:CAI23049.1 xref: UniProtKB:Q9H202 xref: UniProtKB:Q9H8Q8 xref: UniProtKB:Q9HB90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019794 ! RRAGC_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004046 ! GDP binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015847 ! rraga-rragc physical interaction relationship: participates_in CCO:I0016330 ! rraga-rragc-3 physical interaction relationship: participates_in CCO:I0016332 ! rragb-rragc-1 physical interaction relationship: participates_in CCO:I0016334 ! rragc-rraga-4 physical interaction relationship: participates_in CCO:I0017937 ! rraga-rragc-2 physical interaction relationship: participates_in CCO:I0017939 ! rragc-rraga-5 physical interaction relationship: participates_in CCO:I0017940 ! rraga-rragc-4 physical interaction relationship: participates_in CCO:I0017941 ! rragc-rraga-6 physical interaction relationship: participates_in CCO:I0018098 ! rraga-rragc-1 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058782 name: PATZ1_HUMAN def: "POZ-, AT hook-, and zinc finger-containing protein 1" [UniProtKB:Q9HBE1] synonym: "BTB-POZ domain zinc finger transcription factor" EXACT [UniProtKB:Q9HBE1] synonym: "Protein kinase A RI subunit alpha-associated protein" EXACT [UniProtKB:Q9HBE1] synonym: "Zinc finger and BTB domain-containing protein 19" EXACT [UniProtKB:Q9HBE1] synonym: "Zinc finger protein 278" EXACT [UniProtKB:Q9HBE1] synonym: "Zinc finger sarcoma gene protein" EXACT [UniProtKB:Q9HBE1] xref: EMBL:AAF01349.1 xref: EMBL:AAF32518.1 xref: EMBL:AAG09031.1 xref: EMBL:AAG09032.1 xref: EMBL:AAG09033.1 xref: EMBL:AAG09034.1 xref: EMBL:AAH21091.1 xref: EMBL:AAK19024.1 xref: EMBL:CAB51404.1 xref: EMBL:CAG30499.1 xref: UniProtKB:Q9HBE1 xref: UniProtKB:Q9HBE2 xref: UniProtKB:Q9HBE3 xref: UniProtKB:Q9P1A9 xref: UniProtKB:Q9UDU0 xref: UniProtKB:Q9Y529 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019303 ! PATZ1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058783 name: IL21_HUMAN def: "Interleukin-21 precursor" [UniProtKB:Q9HBE4] synonym: "IL-21" EXACT [UniProtKB:Q9HBE4] synonym: "Za11" EXACT [UniProtKB:Q9HBE4] xref: EMBL:AAG29348.1 xref: EMBL:AAH66258.1 xref: EMBL:AAH66259.1 xref: EMBL:AAH66260.1 xref: EMBL:AAH66261.1 xref: EMBL:AAH66262.1 xref: EMBL:AAH69124.1 xref: EMBL:AAU88182.1 xref: EMBL:ABG36529.1 xref: UniProtKB:A5J0L4 xref: UniProtKB:Q9HBE4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018257 ! IL21_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding relationship: has_function CCO:F0001436 ! interleukin-2 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process [Term] id: CCO:B0058784 name: RHOF_HUMAN def: "Rho-related GTP-binding protein RhoF precursor" [UniProtKB:Q9HBH0] synonym: "Rho family GTPase Rif" EXACT [UniProtKB:Q9HBH0] synonym: "Rho in filopodia" EXACT [UniProtKB:Q9HBH0] xref: EMBL:AAG24952.1 xref: EMBL:AAH18208.1 xref: EMBL:BAA91034.1 xref: UniProtKB:Q8WVB1 xref: UniProtKB:Q9HBH0 xref: UniProtKB:Q9NXH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019732 ! RHOF_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0070011 ! RHOF_HUMAN-Cysteine methyl ester208 [Term] id: CCO:B0058785 name: DEFM_HUMAN def: "Peptide deformylase, mitochondrial precursor" [UniProtKB:Q9HBH1] synonym: "EC 3.5.1.88" EXACT [UniProtKB:Q9HBH1] synonym: "Polypeptide deformylase" EXACT [UniProtKB:Q9HBH1] xref: EMBL:AAG33968.1 xref: EMBL:AAH19912.1 xref: EMBL:AAK15624.1 xref: UniProtKB:Q8WUN6 xref: UniProtKB:Q9HBH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017551 ! PDF_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005686 ! peptide deformylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0058786 name: MKNK2_HUMAN def: "MAP kinase-interacting serine/threonine-protein kinase 2" [UniProtKB:Q9HBH9] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9HBH9] synonym: "MAP kinase signal-integrating kinase 2" EXACT [UniProtKB:Q9HBH9] synonym: "Mnk2" EXACT [UniProtKB:Q9HBH9] xref: EMBL:AAF17226.1 xref: EMBL:AAG26336.1 xref: EMBL:AAG26337.1 xref: EMBL:AAH73140.1 xref: UniProtKB:Q6GPI3 xref: UniProtKB:Q9HBH8 xref: UniProtKB:Q9HBH9 xref: UniProtKB:Q9UHR0 xref: UniProtKB:Q9Y2N6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018634 ! MKNK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0068223 ! MKNK2_HUMAN-Phosphothreonine244 relationship: transforms_into CCO:B0068224 ! MKNK2_HUMAN-Phosphothreonine249 relationship: transforms_into CCO:B0068225 ! MKNK2_HUMAN-Phosphothreonine379 [Term] id: CCO:B0058787 name: Q9HBN3_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q9HBN3] synonym: "Polymerase (DNA directed), lambda" EXACT [UniProtKB:Q9HBN3] synonym: "Polymerase (DNA directed), lambda, isoform CRA_i" EXACT [UniProtKB:Q9HBN3] xref: EMBL:AAG17269.1 xref: EMBL:CAI41028.1 xref: EMBL:EAW49765.1 xref: UniProtKB:Q9HBN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017609 ! POLL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058788 name: Q9HBP3_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q9HBP3] xref: EMBL:AAG17257.1 xref: UniProtKB:Q9HBP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058789 name: Q9HBR4_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q9HBR4] synonym: "Putative uncharacterized protein PP838" EXACT [UniProtKB:Q9HBR4] synonym: "Zinc finger protein 3 (A8-51), isoform CRA_d" EXACT [UniProtKB:Q9HBR4] xref: EMBL:AAG17231.1 xref: EMBL:AAG22485.1 xref: EMBL:EAW76606.1 xref: UniProtKB:Q9HBR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020973 ! ZNF3_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058790 name: ZN287_HUMAN def: "Zinc finger protein 287" [UniProtKB:Q9HBT7] synonym: "Zinc finger protein with KRAB and SCAN domains 13" EXACT [UniProtKB:Q9HBT7] xref: EMBL:AAG09702.1 xref: EMBL:AAI01488.1 xref: EMBL:AAI13364.1 xref: EMBL:CAG33475.1 xref: UniProtKB:Q6IAG1 xref: UniProtKB:Q9HBT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020695 ! ZNF287_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0058791 name: Z286A_HUMAN def: "Zinc finger protein 286A" [UniProtKB:Q9HBT8] xref: EMBL:AAG09701.1 xref: EMBL:BAB47503.2 xref: UniProtKB:Q96JF3 xref: UniProtKB:Q9HBT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020518 ! ZNF286A_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058792 name: BARX1_HUMAN def: "Homeobox protein BarH-like 1" [UniProtKB:Q9HBU1] xref: EMBL:AAG23738.1 xref: EMBL:AAH09458.1 xref: EMBL:AAH64363.1 xref: EMBL:CAQ06883.1 xref: EMBL:CAQ06884.1 xref: EMBL:EAW62873.1 xref: UniProtKB:Q6P2R4 xref: UniProtKB:Q96GH8 xref: UniProtKB:Q9HBU1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017127 ! BARX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058793 name: ELTD1_HUMAN def: "EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor" [UniProtKB:Q9HBW9] synonym: "EGF-TM7-latrophilin-related protein" EXACT [UniProtKB:Q9HBW9] synonym: "ETL protein" EXACT [UniProtKB:Q9HBW9] xref: EMBL:AAG33021.1 xref: EMBL:AAH25721.1 xref: EMBL:AAQ88726.1 xref: EMBL:CAI13205.1 xref: EMBL:EAX06345.1 xref: UniProtKB:B1AR71 xref: UniProtKB:Q9HBW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017699 ! ELTD1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0058794 name: LGR6_HUMAN def: "Leucine-rich repeat-containing G-protein coupled receptor 6 precursor" [UniProtKB:Q9HBX8] xref: EMBL:AAG17168.1 xref: EMBL:AAH47905.2 xref: EMBL:AAQ88486.1 xref: EMBL:BAB39854.1 xref: EMBL:BAB55071.1 xref: EMBL:BAB89329.1 xref: EMBL:CAI15927.1 xref: EMBL:CAI15929.1 xref: EMBL:CAI15930.1 xref: UniProtKB:Q5T509 xref: UniProtKB:Q5T512 xref: UniProtKB:Q6UY15 xref: UniProtKB:Q86VU0 xref: UniProtKB:Q96K69 xref: UniProtKB:Q9BYD7 xref: UniProtKB:Q9HBX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018483 ! LGR6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0067643 ! LGR6_HUMAN-Phosphoserine457 [Term] id: CCO:B0058795 name: NOD2_HUMAN def: "Nucleotide-binding oligomerization domain-containing protein 2" [UniProtKB:Q9HC29] synonym: "Caspase recruitment domain-containing protein 15" EXACT [UniProtKB:Q9HC29] synonym: "Inflammatory bowel disease protein 1" EXACT [UniProtKB:Q9HC29] xref: EMBL:AAG33677.1 xref: EMBL:AAK70867.1 xref: EMBL:AAK70868.1 xref: EMBL:CAC42117.1 xref: UniProtKB:Q96RH5 xref: UniProtKB:Q96RH6 xref: UniProtKB:Q96RH8 xref: UniProtKB:Q9HC29 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018816 ! NOD2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005001 ! muramyl dipeptide binding relationship: has_function CCO:F0005721 ! peptidoglycan binding relationship: has_function CCO:F0008000 ! CARD domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000530 ! signalosome relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0001374 ! vesicle relationship: participates_in CCO:P0000535 ! toll-like receptor signaling pathway relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity [Term] id: CCO:B0058796 name: GPBL1_HUMAN def: "Vasculin-like protein 1" [UniProtKB:Q9HC44] synonym: "GC-rich promoter-binding protein 1-like 1" EXACT [UniProtKB:Q9HC44] xref: EMBL:AAG17978.1 xref: EMBL:AAH15713.1 xref: EMBL:AAH22218.1 xref: EMBL:AAH52257.1 xref: EMBL:BAB15047.1 xref: EMBL:CAD38884.1 xref: EMBL:CAI16664.1 xref: EMBL:EAX06959.1 xref: UniProtKB:Q9H751 xref: UniProtKB:Q9HC44 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017993 ! GPBP1L1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015265 ! dkfzp434h1428-eif3s6 physical interaction relationship: participates_in CCO:I0015324 ! dkfzp434h142-plekhf2 physical interaction relationship: participates_in CCO:I0015476 ! dkfzp434h1428-ewsr1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066537 ! GPBL1_HUMAN-Phosphoserine49 [Term] id: CCO:B0058797 name: CBX8_HUMAN def: "Chromobox protein homolog 8" [UniProtKB:Q9HC52] synonym: "hPc3" EXACT [UniProtKB:Q9HC52] synonym: "Pc3" EXACT [UniProtKB:Q9HC52] synonym: "Polycomb 3 homolog" EXACT [UniProtKB:Q9HC52] synonym: "Rectachrome 1" EXACT [UniProtKB:Q9HC52] xref: EMBL:AAF76328.2 xref: EMBL:AAG09180.1 xref: EMBL:AAH08937.1 xref: EMBL:AAH09376.1 xref: EMBL:AAH19289.1 xref: EMBL:BAC11061.1 xref: UniProtKB:Q96H39 xref: UniProtKB:Q9HC52 xref: UniProtKB:Q9NR07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017253 ! CBX8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019682 ! cbx8-eef1g physical interaction relationship: participates_in CCO:I0019683 ! cbx8-htatip physical interaction relationship: participates_in CCO:I0019684 ! cbx8-myst2 physical interaction relationship: participates_in CCO:I0019685 ! cbx8-unc119 physical interaction relationship: participates_in CCO:I0019940 ! cbx8-hap1 physical interaction relationship: participates_in CCO:I0019941 ! cbx8-setdb1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064105 ! CBX8_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0064106 ! CBX8_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0064107 ! CBX8_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0064108 ! CBX8_HUMAN-Phosphoserine265 relationship: transforms_into CCO:B0064109 ! CBX8_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0064110 ! CBX8_HUMAN-Phosphoserine352 [Term] id: CCO:B0058798 name: WFDC1_HUMAN def: "WAP four-disulfide core domain protein 1 precursor" [UniProtKB:Q9HC57] synonym: "Prostate stromal protein ps20" EXACT [UniProtKB:Q9HC57] synonym: "ps20 growth inhibitor" EXACT [UniProtKB:Q9HC57] xref: EMBL:AAG15263.1 xref: EMBL:AAG16647.1 xref: EMBL:AAH29159.1 xref: EMBL:BAC11377.1 xref: UniProtKB:Q8NC27 xref: UniProtKB:Q9HAU1 xref: UniProtKB:Q9HC57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020474 ! WFDC1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0004441 ! protease inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0058799 name: ZBT20_HUMAN def: "Zinc finger and BTB domain-containing protein 20" [UniProtKB:Q9HC78] synonym: "Dendritic-derived BTB/POZ zinc finger protein" EXACT [UniProtKB:Q9HC78] synonym: "Zinc finger protein 288" EXACT [UniProtKB:Q9HC78] xref: EMBL:AAG28340.2 xref: EMBL:AAH29041.1 xref: EMBL:CAB43377.1 xref: EMBL:CAH56190.1 xref: EMBL:EAW79598.1 xref: UniProtKB:Q63HP6 xref: UniProtKB:Q8N6R5 xref: UniProtKB:Q9HC78 xref: UniProtKB:Q9Y410 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020547 ! ZBTB20_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071965 ! ZBT20_HUMAN-Phosphoserine432 [Term] id: CCO:B0058800 name: CAN10_HUMAN def: "Calpain-10" [UniProtKB:Q9HC96] synonym: "Calcium-activated neutral proteinase 10" EXACT [UniProtKB:Q9HC96] synonym: "CANP 10" EXACT [UniProtKB:Q9HC96] synonym: "EC 3.4.22.-" EXACT [UniProtKB:Q9HC96] xref: EMBL:AAG17966.1 xref: EMBL:AAG17968.1 xref: EMBL:AAG17969.1 xref: EMBL:AAG17970.1 xref: EMBL:AAG17971.1 xref: EMBL:AAG17972.1 xref: EMBL:AAG17973.1 xref: EMBL:AAG17974.1 xref: EMBL:AAH04260.1 xref: EMBL:AAH07553.2 xref: EMBL:BAB47474.1 xref: EMBL:BAC11220.1 xref: UniProtKB:A8MVS7 xref: UniProtKB:Q8NCD4 xref: UniProtKB:Q96IG4 xref: UniProtKB:Q96JI2 xref: UniProtKB:Q9HC89 xref: UniProtKB:Q9HC90 xref: UniProtKB:Q9HC91 xref: UniProtKB:Q9HC92 xref: UniProtKB:Q9HC93 xref: UniProtKB:Q9HC94 xref: UniProtKB:Q9HC95 xref: UniProtKB:Q9HC96 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0013661 ! CAPN10_human relationship: has_function CCO:F0000027 ! SNARE binding relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000667 ! calcium-dependent cysteine-type endopeptidase activity relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000243 ! cell relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0001532 ! positive regulation of insulin secretion relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0058801 name: HES4_HUMAN def: "Transcription factor HES-4" [UniProtKB:Q9HCC6] synonym: "bHLH factor Hes4" EXACT [UniProtKB:Q9HCC6] synonym: "Hairy and enhancer of split 4" EXACT [UniProtKB:Q9HCC6] xref: EMBL:AAH12351.1 xref: EMBL:BAB13510.1 xref: EMBL:CAI15572.1 xref: UniProtKB:Q5SVA5 xref: UniProtKB:Q9HCC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018120 ! HES4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058802 name: NCOA5_HUMAN def: "Nuclear receptor coactivator 5" [UniProtKB:Q9HCD5] synonym: "CIA" EXACT [UniProtKB:Q9HCD5] synonym: "Coactivator independent of AF-2" EXACT [UniProtKB:Q9HCD5] synonym: "NCoA-5" EXACT [UniProtKB:Q9HCD5] xref: EMBL:AAG36793.1 xref: EMBL:AAO33457.1 xref: EMBL:BAB13463.1 xref: EMBL:CAH74052.1 xref: EMBL:CAI42972.1 xref: UniProtKB:Q6HA99 xref: UniProtKB:Q9H1F2 xref: UniProtKB:Q9H2T2 xref: UniProtKB:Q9H4Y9 xref: UniProtKB:Q9HCD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018730 ! NCOA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068481 ! NCOA5_HUMAN-Phosphotyrosine127 relationship: transforms_into CCO:B0068482 ! NCOA5_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0068483 ! NCOA5_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0068484 ! NCOA5_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0068485 ! NCOA5_HUMAN-Phosphoserine381 relationship: transforms_into CCO:B0068486 ! NCOA5_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0068487 ! NCOA5_HUMAN-Phosphoserine404 relationship: transforms_into CCO:B0068488 ! NCOA5_HUMAN-Phosphothreonine420 [Term] id: CCO:B0058803 name: ZN532_HUMAN def: "Zinc finger protein 532" [UniProtKB:Q9HCE3] xref: EMBL:AAH36366.1 xref: EMBL:AAI30619.1 xref: EMBL:AAI30621.1 xref: EMBL:AAK72122.1 xref: EMBL:BAA91755.1 xref: EMBL:BAB13455.1 xref: UniProtKB:Q4G0V6 xref: UniProtKB:Q7L7Z7 xref: UniProtKB:Q96QR7 xref: UniProtKB:Q9HCE3 xref: UniProtKB:Q9NVJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020802 ! ZNF532_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072141 ! ZN532_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0072142 ! ZN532_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0072143 ! ZN532_HUMAN-Phosphoserine134 relationship: transforms_into CCO:B0072144 ! ZN532_HUMAN-Phosphothreonine205 relationship: transforms_into CCO:B0072145 ! ZN532_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0072146 ! ZN532_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0072147 ! ZN532_HUMAN-Phosphoserine269 [Term] id: CCO:B0058804 name: ARGAL_HUMAN def: "Rho guanine nucleotide exchange factor 10-like protein" [UniProtKB:Q9HCE6] synonym: "GrinchGEF" EXACT [UniProtKB:Q9HCE6] xref: EMBL:AAH65561.1 xref: EMBL:AAH80596.1 xref: EMBL:AAI17172.1 xref: EMBL:AAZ73162.1 xref: EMBL:BAA91663.1 xref: EMBL:BAB13452.1 xref: EMBL:BAC03792.1 xref: EMBL:CAH74135.1 xref: EMBL:CAH74136.1 xref: EMBL:CAI22139.1 xref: EMBL:CAI22140.1 xref: UniProtKB:Q17RW1 xref: UniProtKB:Q3YFJ4 xref: UniProtKB:Q5VXI5 xref: UniProtKB:Q5VXI6 xref: UniProtKB:Q66K51 xref: UniProtKB:Q6P0L7 xref: UniProtKB:Q8NAV5 xref: UniProtKB:Q9HCE6 xref: UniProtKB:Q9NVT3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021147 ! ARHGEF10L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020554 ! kiaa1626-anxa9 physical interaction relationship: participates_in CCO:I0020555 ! kiaa1626-drap1 physical interaction relationship: participates_in CCO:I0020556 ! kiaa1626-nr4a1 physical interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0065709 ! ARGAL_HUMAN-Phosphotyrosine131 relationship: transforms_into CCO:B0065710 ! ARGAL_HUMAN-Phosphotyrosine152 [Term] id: CCO:B0058805 name: SMUF1_HUMAN def: "E3 ubiquitin-protein ligase SMURF1" [UniProtKB:Q9HCE7] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9HCE7] synonym: "hSMURF1" EXACT [UniProtKB:Q9HCE7] synonym: "Smad ubiquitination regulatory factor 1" EXACT [UniProtKB:Q9HCE7] synonym: "Smad-specific E3 ubiquitin ligase 1" EXACT [UniProtKB:Q9HCE7] xref: EMBL:AAC62434.1 xref: EMBL:AAF08298.2 xref: EMBL:BAB13451.1 xref: UniProtKB:O75853 xref: UniProtKB:Q9HCE7 xref: UniProtKB:Q9UJT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019956 ! SMURF1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0018239 ! smurf-runx2 physical interaction relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001275 ! negative regulation of BMP signaling pathway [Term] id: CCO:B0058806 name: ZN160_HUMAN def: "Zinc finger protein 160" [UniProtKB:Q9HCG1] synonym: "HKr18" EXACT [UniProtKB:Q9HCG1] synonym: "HZF5" EXACT [UniProtKB:Q9HCG1] synonym: "Zinc finger protein 5" EXACT [UniProtKB:Q9HCG1] synonym: "Zinc finger protein Kr18" EXACT [UniProtKB:Q9HCG1] xref: EMBL:AAH94880.1 xref: EMBL:AAK61306.1 xref: EMBL:BAB13437.1 xref: EMBL:BAB15732.1 xref: EMBL:CAA55528.1 xref: UniProtKB:Q14589 xref: UniProtKB:Q504Q8 xref: UniProtKB:Q96JC5 xref: UniProtKB:Q9H7N6 xref: UniProtKB:Q9HCG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020635 ! ZNF160_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072056 ! ZN160_HUMAN-Phosphothreonine588 [Term] id: CCO:B0058807 name: NCM_HUMAN def: "Nucampholin homolog" [UniProtKB:Q9HCG8] synonym: "fSAPb" EXACT [UniProtKB:Q9HCG8] xref: EMBL:AAH16651.1 xref: EMBL:AAH31216.1 xref: EMBL:AAH53573.1 xref: EMBL:AAH57826.1 xref: EMBL:AAH93952.1 xref: EMBL:AAH93954.1 xref: EMBL:BAB13430.1 xref: EMBL:BAB15197.1 xref: EMBL:BAB15612.1 xref: UniProtKB:Q05DC2 xref: UniProtKB:Q4G135 xref: UniProtKB:Q52LF0 xref: UniProtKB:Q6PEX2 xref: UniProtKB:Q7Z6I0 xref: UniProtKB:Q9H5L3 xref: UniProtKB:Q9H6Q6 xref: UniProtKB:Q9HCG8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018727 ! NCM_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0017315 ! exosc8-kiaa1604 physical interaction relationship: participates_in CCO:P0002767 ! regulation of nuclear mRNA splicing, via spliceosome [Term] id: CCO:B0058808 name: NGL1_HUMAN def: "Netrin-G1 ligand precursor" [UniProtKB:Q9HCJ2] synonym: "Leucine-rich repeat-containing protein 4C" EXACT [UniProtKB:Q9HCJ2] synonym: "NGL-1" EXACT [UniProtKB:Q9HCJ2] xref: EMBL:AAH41374.3 xref: EMBL:AAQ88660.1 xref: EMBL:BAB13406.1 xref: UniProtKB:Q7L0N3 xref: UniProtKB:Q9HCJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018786 ! LRRC4C_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002948 ! regulation of axonogenesis [Term] id: CCO:B0058809 name: ZBT26_HUMAN def: "Zinc finger and BTB domain-containing protein 26" [UniProtKB:Q9HCK0] synonym: "Zinc finger protein 481" EXACT [UniProtKB:Q9HCK0] synonym: "Zinc finger protein Bioref" EXACT [UniProtKB:Q9HCK0] xref: EMBL:AAH18748.1 xref: EMBL:AAL55969.1 xref: EMBL:BAB13398.1 xref: UniProtKB:Q8WTR1 xref: UniProtKB:Q9HCK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020551 ! ZBTB26_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058810 name: ROBO2_HUMAN def: "Roundabout homolog 2 precursor" [UniProtKB:Q9HCK4] xref: EMBL:AAC39576.1 xref: EMBL:AAH64374.1 xref: EMBL:BAB13394.1 xref: UniProtKB:O43608 xref: UniProtKB:Q9HCK4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019763 ! ROBO2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001690 ! axon guidance receptor activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018896 ! ubqln4-robo2 physical interaction relationship: participates_in CCO:I0019231 ! robo1-robo2 physical interaction relationship: participates_in CCO:I0020277 ! cpe-robo2 physical interaction relationship: participates_in CCO:I0020614 ! olfm2-robo2 physical interaction relationship: participates_in CCO:I0020630 ! ppp1r1b-robo2 physical interaction relationship: participates_in CCO:I0020670 ! ssrp1-robo2 physical interaction relationship: participates_in CCO:P0002950 ! positive regulation of axonogenesis [Term] id: CCO:B0058811 name: ZFP14_HUMAN def: "Zinc finger protein 14 homolog" [UniProtKB:Q9HCL3] synonym: "Zfp-14" EXACT [UniProtKB:Q9HCL3] synonym: "Zinc finger protein 531" EXACT [UniProtKB:Q9HCL3] xref: EMBL:BAB13385.1 xref: UniProtKB:Q9HCL3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020585 ! ZFP14_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058812 name: PLXA4_HUMAN def: "Plexin-A4 precursor" [UniProtKB:Q9HCM2] xref: EMBL:AAH28744.1 xref: EMBL:AAQ89209.1 xref: EMBL:BAB13376.3 xref: EMBL:BAC04587.1 xref: EMBL:BAC85615.1 xref: EMBL:CAB70707.1 xref: EMBL:CAD39161.3 xref: UniProtKB:Q6UWC6 xref: UniProtKB:Q6ZW89 xref: UniProtKB:Q8N969 xref: UniProtKB:Q8ND00 xref: UniProtKB:Q8NEN3 xref: UniProtKB:Q9HCM2 xref: UniProtKB:Q9NTD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019449 ! PLXNA4_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069426 ! PLXA4_HUMAN-Phosphoserine946 [Term] id: CCO:B0058813 name: GPN1_HUMAN def: "GPN-loop GTPase 1" [UniProtKB:Q9HCN4] synonym: "MBD2-interacting protein" EXACT [UniProtKB:Q9HCN4] synonym: "MBDin" EXACT [UniProtKB:Q9HCN4] synonym: "XPA-binding protein 1" EXACT [UniProtKB:Q9HCN4] xref: EMBL:AAH07451.1 xref: EMBL:BAB17612.1 xref: EMBL:CAA09376.1 xref: UniProtKB:O76004 xref: UniProtKB:Q9HCN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022287 ! GPN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015165 ! xab1-zbed1x physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0066540 ! GPN1_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0066541 ! GPN1_HUMAN-Phosphoserine314 relationship: transforms_into CCO:B0066542 ! GPN1_HUMAN-Phosphoserine338 [Term] id: CCO:B0058814 name: GPVI_HUMAN def: "Platelet glycoprotein VI precursor" [UniProtKB:Q9HCN6] xref: EMBL:AAI04833.1 xref: EMBL:AAI11964.1 xref: EMBL:BAA89353.1 xref: EMBL:BAB12245.1 xref: EMBL:BAB12246.1 xref: EMBL:BAB12247.1 xref: UniProtKB:Q9HCN6 xref: UniProtKB:Q9HCN7 xref: UniProtKB:Q9UIF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018046 ! GP6_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001649 ! collagen binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000710 ! enzyme linked receptor protein signaling pathway [Term] id: CCO:B0058815 name: HHATL_HUMAN def: "Protein-cysteine N-palmitoyltransferase HHAT-like protein" [UniProtKB:Q9HCP6] synonym: "Glycerol uptake/transporter homolog" EXACT [UniProtKB:Q9HCP6] synonym: "Hedgehog acyltransferase-like protein" EXACT [UniProtKB:Q9HCP6] xref: EMBL:AAH22529.1 xref: EMBL:BAA86487.1 xref: EMBL:BAB17758.1 xref: UniProtKB:Q8TBG3 xref: UniProtKB:Q9HCP6 xref: UniProtKB:Q9ULP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018129 ! HHATL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0003300 ! negative regulation of N-terminal protein palmitoylation [Term] id: CCO:B0058816 name: Q9HCP9_HUMAN def: "Phosphodiesterase 10A1 (PDE10A1)" [UniProtKB:Q9HCP9] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q9HCP9] xref: EMBL:BAB16383.1 xref: UniProtKB:Q9HCP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021268 ! HSPDE10A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058817 name: RFRP_HUMAN def: "FMRFamide-related peptides precursor" [UniProtKB:Q9HCQ7] synonym: "Neuropeptide VF" EXACT [UniProtKB:Q9HCQ7] xref: EMBL:AAK94201.1 xref: EMBL:AAL90453.1 xref: EMBL:AAL90458.1 xref: EMBL:AAP22339.1 xref: EMBL:BAB17674.1 xref: UniProtKB:Q7LE27 xref: UniProtKB:Q96PI9 xref: UniProtKB:Q9HCQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019683 ! NPVF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0069900 ! RFRP_HUMAN-Phenylalanine amide92 relationship: transforms_into CCO:B0069901 ! RFRP_HUMAN-Phenylalanine amide131 [Term] id: CCO:B0058818 name: PDE11_HUMAN def: "Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A" [UniProtKB:Q9HCR9] synonym: "cAMP and cGMP phosphodiesterase 11A" EXACT [UniProtKB:Q9HCR9] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q9HCR9] synonym: "EC 3.1.4.35" EXACT [UniProtKB:Q9HCR9] xref: EMBL:AAG32023.1 xref: EMBL:AAI12394.1 xref: EMBL:AAI14432.1 xref: EMBL:AAY14803.1 xref: EMBL:BAB16371.1 xref: EMBL:BAB16372.1 xref: EMBL:BAB62712.1 xref: EMBL:BAB62713.2 xref: EMBL:BAB62714.1 xref: EMBL:CAB82573.1 xref: EMBL:CAC15567.1 xref: UniProtKB:Q14CD1 xref: UniProtKB:Q53T16 xref: UniProtKB:Q96S76 xref: UniProtKB:Q9GZY7 xref: UniProtKB:Q9HB46 xref: UniProtKB:Q9HCR9 xref: UniProtKB:Q9NY45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019331 ! PDE11A_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000584 ! cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006858 ! 3',5'-cyclic-GMP phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058819 name: PREB_HUMAN def: "Prolactin regulatory element-binding protein" [UniProtKB:Q9HCU5] synonym: "Mammalian guanine nucleotide exchange factor mSec12" EXACT [UniProtKB:Q9HCU5] xref: EMBL:AAF19192.1 xref: EMBL:AAF74572.1 xref: EMBL:AAG01692.1 xref: EMBL:AAH02765.1 xref: EMBL:AAH12890.1 xref: EMBL:AAH16472.1 xref: EMBL:AAH41032.1 xref: EMBL:BAB14385.1 xref: UniProtKB:Q9HCU5 xref: UniProtKB:Q9UH94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019505 ! PREB_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058820 name: ZN304_HUMAN def: "Zinc finger protein 304" [UniProtKB:Q9HCX3] xref: EMBL:CAC06610.1 xref: UniProtKB:Q9HCX3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020698 ! ZNF304_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058821 name: Q9HCY4_HUMAN def: "DJ1186N24.3 (Novel zinc finger protein)" [UniProtKB:Q9HCY4] xref: EMBL:CAB71122.1 xref: UniProtKB:Q9HCY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021269 ! dJ1186N24.3_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058822 name: ZN334_HUMAN def: "Zinc finger protein 334" [UniProtKB:Q9HCZ1] xref: EMBL:AAH24177.1 xref: EMBL:BAA91630.1 xref: EMBL:CAI12459.1 xref: EMBL:CAI42502.1 xref: UniProtKB:Q5T6U2 xref: UniProtKB:Q9HCZ1 xref: UniProtKB:Q9NVW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020709 ! ZNF334_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058823 name: SRA1_HUMAN def: "Steroid receptor RNA activator 1" [UniProtKB:Q9HD15] synonym: "SRAP" EXACT [UniProtKB:Q9HD15] synonym: "Steroid receptor RNA activator protein" EXACT [UniProtKB:Q9HD15] xref: EMBL:AAG02114.1 xref: EMBL:AAG02115.1 xref: EMBL:AAG02116.1 xref: EMBL:AAH40043.2 xref: EMBL:AAH67895.1 xref: EMBL:AAL55868.1 xref: UniProtKB:Q6NVU9 xref: UniProtKB:Q8IXM1 xref: UniProtKB:Q9HD13 xref: UniProtKB:Q9HD14 xref: UniProtKB:Q9HD15 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020033 ! SRA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0070861 ! SRA1_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0070862 ! SRA1_HUMAN-Phosphothreonine68 [Term] id: CCO:B0058824 name: Q9HD50_HUMAN def: "Uncharacterized gastric protein ZG24P" [UniProtKB:Q9HD50] xref: EMBL:AAG03020.1 xref: UniProtKB:Q9HD50 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058825 name: Q9HD57_HUMAN def: "Uncharacterized gastric protein YA42P" [UniProtKB:Q9HD57] xref: EMBL:AAG03013.1 xref: UniProtKB:Q9HD57 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058826 name: MYO10_HUMAN def: "Myosin-X" [UniProtKB:Q9HD67] synonym: "Unconventional myosin-10" EXACT [UniProtKB:Q9HD67] xref: EMBL:AAF17363.1 xref: EMBL:AAF36524.1 xref: EMBL:AAF36525.1 xref: EMBL:AAF37875.1 xref: EMBL:AAF68025.2 xref: EMBL:BAA34519.2 xref: UniProtKB:O94893 xref: UniProtKB:Q9HD67 xref: UniProtKB:Q9NYM7 xref: UniProtKB:Q9P110 xref: UniProtKB:Q9P111 xref: UniProtKB:Q9UHF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018699 ! MYO10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020627 ! pla2g10-myo10 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068388 ! MYO10_HUMAN-Phosphoserine960 relationship: transforms_into CCO:B0068389 ! MYO10_HUMAN-Phosphoserine962 relationship: transforms_into CCO:B0068390 ! MYO10_HUMAN-Phosphoserine968 relationship: transforms_into CCO:B0068391 ! MYO10_HUMAN-Phosphoserine969 relationship: transforms_into CCO:B0068392 ! MYO10_HUMAN-Phosphoserine1007 [Term] id: CCO:B0058827 name: Q9HD74_HUMAN def: "Zinc finger protein SBZF3" [UniProtKB:Q9HD74] xref: EMBL:AAF99600.1 xref: UniProtKB:Q9HD74 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058828 name: NDF4_HUMAN def: "Neurogenic differentiation factor 4" [UniProtKB:Q9HD90] synonym: "ATH-3" EXACT [UniProtKB:Q9HD90] synonym: "Atoh3" EXACT [UniProtKB:Q9HD90] synonym: "NeuroD4" EXACT [UniProtKB:Q9HD90] synonym: "Protein atonal homolog 3" EXACT [UniProtKB:Q9HD90] xref: EMBL:AAF99097.1 xref: UniProtKB:Q9HD90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018736 ! NEUROD4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058829 name: CD209_HUMAN def: "CD209 antigen" [UniProtKB:Q9NNX6] synonym: "C-type lectin domain family 4 member L" EXACT [UniProtKB:Q9NNX6] synonym: "CD209 antigen" EXACT [UniProtKB:Q9NNX6] synonym: "DC-SIGN" EXACT [UniProtKB:Q9NNX6] synonym: "DC-SIGN1" EXACT [UniProtKB:Q9NNX6] synonym: "Dendritic cell-specific ICAM-3-grabbing non-integrin 1" EXACT [UniProtKB:Q9NNX6] xref: EMBL:AAF77072.1 xref: EMBL:AAG13814.1 xref: EMBL:AAK20997.1 xref: EMBL:AAK91846.1 xref: EMBL:AAK91847.1 xref: EMBL:AAK91848.1 xref: EMBL:AAK91849.1 xref: EMBL:AAK91850.1 xref: EMBL:AAK91851.1 xref: EMBL:AAK91852.1 xref: EMBL:AAK91853.1 xref: EMBL:AAK91854.1 xref: EMBL:AAK91855.1 xref: EMBL:AAK91856.1 xref: EMBL:AAK91857.1 xref: EMBL:AAK91858.1 xref: UniProtKB:Q96QP7 xref: UniProtKB:Q96QP8 xref: UniProtKB:Q96QP9 xref: UniProtKB:Q96QQ0 xref: UniProtKB:Q96QQ1 xref: UniProtKB:Q96QQ2 xref: UniProtKB:Q96QQ3 xref: UniProtKB:Q96QQ4 xref: UniProtKB:Q96QQ5 xref: UniProtKB:Q96QQ6 xref: UniProtKB:Q96QQ7 xref: UniProtKB:Q96QQ8 xref: UniProtKB:Q9NNX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017288 ! CD209_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001662 ! mannose binding relationship: has_function CCO:F0005690 ! exogenous peptide antigen binding relationship: has_function CCO:F0006246 ! virion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058830 name: HMX1_HUMAN def: "Homeobox protein HMX1" [UniProtKB:Q9NP08] synonym: "Homeobox protein H6" EXACT [UniProtKB:Q9NP08] xref: EMBL:AAF70205.1 xref: UniProtKB:Q9NP08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018146 ! HMX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058831 name: Q9NP35_HUMAN def: "AS10 protein" [UniProtKB:Q9NP35] xref: EMBL:AAF35252.1 xref: UniProtKB:Q9NP35 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0058832 name: IRPL2_HUMAN def: "X-linked interleukin-1 receptor accessory protein-like 2 precursor" [UniProtKB:Q9NP60] synonym: "IL-1 receptor accessory protein-like 2" EXACT [UniProtKB:Q9NP60] synonym: "IL-1R9" EXACT [UniProtKB:Q9NP60] synonym: "IL1RAPL-2-related protein" EXACT [UniProtKB:Q9NP60] synonym: "Interleukin-1 receptor 9" EXACT [UniProtKB:Q9NP60] synonym: "Three immunoglobulin domain-containing IL-1 receptor-related 1" EXACT [UniProtKB:Q9NP60] synonym: "TIGIRR-1" EXACT [UniProtKB:Q9NP60] xref: EMBL:AAF59412.1 xref: EMBL:AAF61307.1 xref: EMBL:AAG21370.1 xref: EMBL:CAB86868.1 xref: EMBL:CAB89867.1 xref: UniProtKB:Q9NP60 xref: UniProtKB:Q9NZN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018317 ! IL1RAPL2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_function CCO:F0001257 ! interleukin-1, Type II, blocking receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058833 name: ARFG3_HUMAN def: "ADP-ribosylation factor GTPase-activating protein 3" [UniProtKB:Q9NP61] synonym: "ARF GAP 3" EXACT [UniProtKB:Q9NP61] xref: EMBL:AAF40310.1 xref: EMBL:AAH05122.1 xref: EMBL:BAA92076.1 xref: EMBL:BAB14236.1 xref: EMBL:CAB70834.1 xref: EMBL:CAB76901.1 xref: EMBL:CAG30268.1 xref: EMBL:CAI20950.1 xref: EMBL:CAI21510.1 xref: UniProtKB:Q9BSC6 xref: UniProtKB:Q9H9J0 xref: UniProtKB:Q9NP61 xref: UniProtKB:Q9NT10 xref: UniProtKB:Q9NUP5 xref: UniProtKB:Q9Y4V3 xref: UniProtKB:Q9Y4V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017009 ! ARFGAP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0065705 ! ARFG3_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0065706 ! ARFG3_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0065707 ! ARFG3_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0065708 ! ARFG3_HUMAN-Phosphoserine453 [Term] id: CCO:B0058834 name: GCM1_HUMAN def: "Chorion-specific transcription factor GCMa" [UniProtKB:Q9NP62] synonym: "GCM motif protein 1" EXACT [UniProtKB:Q9NP62] synonym: "Glial cells missing homolog 1" EXACT [UniProtKB:Q9NP62] synonym: "hGCMa" EXACT [UniProtKB:Q9NP62] xref: EMBL:AAH96288.1 xref: EMBL:BAA13651.1 xref: EMBL:BAA77250.2 xref: EMBL:BAA94757.1 xref: EMBL:BAA94758.1 xref: EMBL:BAB18039.1 xref: EMBL:CAI14905.1 xref: UniProtKB:Q4VAQ7 xref: UniProtKB:Q5T0X0 xref: UniProtKB:Q99468 xref: UniProtKB:Q9NP62 xref: UniProtKB:Q9P1X3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017894 ! GCM1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058835 name: WBS14_HUMAN def: "Williams-Beuren syndrome chromosomal region 14 protein" [UniProtKB:Q9NP71] synonym: "Mlx interactor" EXACT [UniProtKB:Q9NP71] synonym: "MLX-interacting protein-like" EXACT [UniProtKB:Q9NP71] synonym: "WS basic-helix-loop-helix leucine zipper protein" EXACT [UniProtKB:Q9NP71] synonym: "WS-bHLH" EXACT [UniProtKB:Q9NP71] xref: EMBL:AAD28084.1 xref: EMBL:AAF68174.1 xref: EMBL:AAF68176.1 xref: EMBL:AAH12925.1 xref: EMBL:AAK20935.1 xref: EMBL:AAK20936.1 xref: EMBL:AAK20937.1 xref: EMBL:AAK20938.1 xref: EMBL:AAK20939.1 xref: UniProtKB:Q96E48 xref: UniProtKB:Q9BY03 xref: UniProtKB:Q9BY04 xref: UniProtKB:Q9BY05 xref: UniProtKB:Q9BY06 xref: UniProtKB:Q9NP71 xref: UniProtKB:Q9Y2P3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020471 ! MLXIPL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002520 ! positive regulation of fatty acid biosynthetic process relationship: participates_in CCO:P0002569 ! positive regulation of glycolysis relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071831 ! WBS14_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0071832 ! WBS14_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0071833 ! WBS14_HUMAN-Phosphothreonine509 [Term] id: CCO:B0058836 name: RAB18_HUMAN def: "Ras-related protein Rab-18" [UniProtKB:Q9NP72] xref: EMBL:AAF61433.1 xref: EMBL:AAG49435.1 xref: EMBL:AAH15014.1 xref: EMBL:AAH29350.1 xref: EMBL:AAM21098.1 xref: EMBL:AAP88842.1 xref: EMBL:AAP97170.1 xref: EMBL:BAD96873.1 xref: EMBL:CAB66668.1 xref: EMBL:CAB86486.1 xref: EMBL:CAG38486.1 xref: EMBL:CAH70590.1 xref: UniProtKB:Q53FX8 xref: UniProtKB:Q6FIH1 xref: UniProtKB:Q9NP72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019575 ! RAB18_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020418 ! rab18-pde6d physical interaction relationship: participates_in CCO:I0020638 ! rab18-tom1l1 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069671 ! RAB18_HUMAN-Phosphothreonine29 [Term] id: CCO:B0058837 name: PALMD_HUMAN def: "Palmdelphin" [UniProtKB:Q9NP74] synonym: "Paralemnin-like protein" EXACT [UniProtKB:Q9NP74] xref: EMBL:AAH12570.1 xref: EMBL:AAL33879.1 xref: EMBL:BAA91047.1 xref: EMBL:BAB14946.1 xref: EMBL:CAC01335.1 xref: EMBL:CAC01336.1 xref: EMBL:CAC01337.1 xref: EMBL:CAC01338.1 xref: EMBL:CAC59692.1 xref: UniProtKB:Q9H7E6 xref: UniProtKB:Q9NP74 xref: UniProtKB:Q9NPM5 xref: UniProtKB:Q9NPM6 xref: UniProtKB:Q9NPS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019296 ! PALMD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0069080 ! PALMD_HUMAN-Phosphoserine135 relationship: transforms_into CCO:B0069081 ! PALMD_HUMAN-Phosphoserine321 relationship: transforms_into CCO:B0069082 ! PALMD_HUMAN-Phosphoserine370 relationship: transforms_into CCO:B0069083 ! PALMD_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0069084 ! PALMD_HUMAN-Phosphoserine515 [Term] id: CCO:B0058838 name: TNR12_HUMAN def: "Tumor necrosis factor receptor superfamily member 12A precursor" [UniProtKB:Q9NP84] synonym: "CD266 antigen" EXACT [UniProtKB:Q9NP84] synonym: "FGF-inducible 14" EXACT [UniProtKB:Q9NP84] synonym: "Fibroblast growth factor-inducible immediate-early response protein 14" EXACT [UniProtKB:Q9NP84] synonym: "Tweak-receptor" EXACT [UniProtKB:Q9NP84] synonym: "TweakR" EXACT [UniProtKB:Q9NP84] xref: EMBL:AAF69108.1 xref: EMBL:AAH02718.1 xref: EMBL:BAA94792.1 xref: EMBL:BAB17850.1 xref: UniProtKB:Q9HCS0 xref: UniProtKB:Q9NP84 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020311 ! TNFRSF12A_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002548 ! positive regulation of axon extension [Term] id: CCO:B0058839 name: CABP5_HUMAN def: "Calcium-binding protein 5" [UniProtKB:Q9NP86] synonym: "CaBP5" EXACT [UniProtKB:Q9NP86] xref: EMBL:AAF25793.1 xref: EMBL:AAF25798.1 xref: EMBL:AAI26134.1 xref: EMBL:AAI26136.1 xref: UniProtKB:A0AUY4 xref: UniProtKB:Q9NP86 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017206 ! CABP5_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058840 name: DPOLM_HUMAN def: "DNA polymerase mu" [UniProtKB:Q9NP87] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9NP87] synonym: "Pol Mu" EXACT [UniProtKB:Q9NP87] xref: EMBL:AAF26284.1 xref: EMBL:AAW65376.1 xref: EMBL:CAB65075.2 xref: UniProtKB:Q9NP87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017610 ! POLM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0064857 ! DPOLM_HUMAN-Phosphoserine12 [Term] id: CCO:B0058841 name: RAB9B_HUMAN def: "Ras-related protein Rab-9B" [UniProtKB:Q9NP90] synonym: "Rab-9L" EXACT [UniProtKB:Q9NP90] synonym: "RAB9-like protein" EXACT [UniProtKB:Q9NP90] xref: EMBL:AAH93756.1 xref: EMBL:AAH93758.1 xref: EMBL:BAA89542.1 xref: EMBL:CAB76967.1 xref: UniProtKB:Q52LX2 xref: UniProtKB:Q9NP90 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019609 ! RAB9B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058842 name: TREM1_HUMAN def: "Triggering receptor expressed on myeloid cells 1 precursor" [UniProtKB:Q9NP99] synonym: "TREM-1" EXACT [UniProtKB:Q9NP99] synonym: "Triggering receptor expressed on monocytes 1" EXACT [UniProtKB:Q9NP99] xref: EMBL:AAF71694.1 xref: EMBL:AAF90197.1 xref: EMBL:AAH17773.1 xref: EMBL:AAL74018.1 xref: EMBL:BAD96984.1 xref: EMBL:CAI19864.1 xref: UniProtKB:Q53FL8 xref: UniProtKB:Q5T2C9 xref: UniProtKB:Q86YU1 xref: UniProtKB:Q9NP99 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020349 ! TREM1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058843 name: ENY2_HUMAN def: "Enhancer of yellow 2 transcription factor homolog" [UniProtKB:Q9NPA8] xref: EMBL:AAF86876.1 xref: EMBL:AAF89829.1 xref: EMBL:AAH07870.1 xref: EMBL:BAF83441.1 xref: EMBL:CAG33464.1 xref: EMBL:EAW91927.1 xref: UniProtKB:Q9NPA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017717 ! ENY2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020283 ! dc6-mcm3ap physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058844 name: NT5M_HUMAN def: "5'(3')-deoxyribonucleotidase, mitochondrial precursor" [UniProtKB:Q9NPB1] synonym: "5',3'-nucleotidase, mitochondrial" EXACT [UniProtKB:Q9NPB1] synonym: "Deoxy-5'-nucleotidase 2" EXACT [UniProtKB:Q9NPB1] synonym: "dNT-2" EXACT [UniProtKB:Q9NPB1] synonym: "EC 3.1.3.-" EXACT [UniProtKB:Q9NPB1] xref: EMBL:AAF87076.1 xref: EMBL:AAH35838.1 xref: EMBL:CAB99251.1 xref: UniProtKB:Q9NPB1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018879 ! NT5M_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001795 ! nucleotidase activity relationship: has_function CCO:F0001796 ! 5'-nucleotidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0058845 name: CABP2_HUMAN def: "Calcium-binding protein 2" [UniProtKB:Q9NPB3] synonym: "CaBP2" EXACT [UniProtKB:Q9NPB3] xref: EMBL:AAF25788.1 xref: EMBL:AAF26283.1 xref: UniProtKB:Q9NPB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017203 ! CABP2_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058846 name: LT4R2_HUMAN def: "Leukotriene B4 receptor 2" [UniProtKB:Q9NPC1] synonym: "Leukotriene B4 receptor BLT2" EXACT [UniProtKB:Q9NPC1] synonym: "LTB4 receptor JULF2" EXACT [UniProtKB:Q9NPC1] synonym: "LTB4-R2" EXACT [UniProtKB:Q9NPC1] synonym: "Seven transmembrane receptor BLTR2" EXACT [UniProtKB:Q9NPC1] xref: EMBL:AAF81261.1 xref: EMBL:AAG40857.1 xref: EMBL:AAP23200.1 xref: EMBL:BAA99539.1 xref: EMBL:BAA99553.1 xref: EMBL:BAB00610.1 xref: EMBL:BAB89317.1 xref: EMBL:CAB96134.1 xref: UniProtKB:Q9NPC1 xref: UniProtKB:Q9NPE5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018529 ! LTB4R2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000182 ! leukotriene B4 receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001314 ! leukotriene receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058847 name: MYNN_HUMAN def: "Myoneurin" [UniProtKB:Q9NPC7] synonym: "Zinc finger and BTB domain-containing protein 31" EXACT [UniProtKB:Q9NPC7] xref: EMBL:AAF73138.1 xref: EMBL:AAF74822.1 xref: EMBL:AAF80160.1 xref: EMBL:AAH33620.1 xref: EMBL:AAP44763.1 xref: EMBL:AAP44764.1 xref: EMBL:AAR99055.1 xref: EMBL:AAR99843.1 xref: EMBL:AAS38566.1 xref: EMBL:AAS38567.1 xref: EMBL:AAS87376.1 xref: EMBL:AAS87377.1 xref: EMBL:BAB13862.1 xref: EMBL:BAC55898.1 xref: EMBL:BAC55899.1 xref: EMBL:BAC55900.1 xref: EMBL:CAB61393.1 xref: EMBL:CAI46035.1 xref: UniProtKB:Q6QHA6 xref: UniProtKB:Q6QHA7 xref: UniProtKB:Q6R3G1 xref: UniProtKB:Q6R3G2 xref: UniProtKB:Q6R4A0 xref: UniProtKB:Q7Z716 xref: UniProtKB:Q7Z717 xref: UniProtKB:Q86Z11 xref: UniProtKB:Q86Z12 xref: UniProtKB:Q9NPC7 xref: UniProtKB:Q9NS01 xref: UniProtKB:Q9UIW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018698 ! MYNN_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058848 name: SIX2_HUMAN def: "Homeobox protein SIX2" [UniProtKB:Q9NPC8] synonym: "Sine oculis homeobox homolog 2" EXACT [UniProtKB:Q9NPC8] xref: EMBL:AAF69031.1 xref: EMBL:AAF69032.1 xref: EMBL:AAK06773.1 xref: EMBL:AAK16581.1 xref: EMBL:AAK16582.1 xref: EMBL:AAK16583.1 xref: EMBL:AAV38903.1 xref: UniProtKB:Q9BXH7 xref: UniProtKB:Q9NPC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019921 ! SIX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058849 name: CD320_HUMAN def: "CD320 antigen precursor" [UniProtKB:Q9NPF0] synonym: "8D6 antigen" EXACT [UniProtKB:Q9NPF0] synonym: "CD320 antigen" EXACT [UniProtKB:Q9NPF0] synonym: "FDC-signaling molecule 8D6" EXACT [UniProtKB:Q9NPF0] synonym: "FDC-SM-8D6" EXACT [UniProtKB:Q9NPF0] synonym: "TCblR" EXACT [UniProtKB:Q9NPF0] synonym: "Transcobalamin receptor" EXACT [UniProtKB:Q9NPF0] xref: EMBL:AAF61850.1 xref: EMBL:AAH00668.1 xref: EMBL:AAH07083.1 xref: EMBL:AAQ88786.1 xref: EMBL:BAD96343.1 xref: EMBL:BAG38022.1 xref: EMBL:CAB66587.1 xref: EMBL:CAB97010.1 xref: EMBL:CAG33455.1 xref: EMBL:EAW68936.1 xref: UniProtKB:B2RDS5 xref: UniProtKB:Q53HF7 xref: UniProtKB:Q9NPF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017296 ! CD320_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0058850 name: CENA2_HUMAN def: "Centaurin-alpha-2" [UniProtKB:Q9NPF8] xref: EMBL:AAH33758.1 xref: EMBL:CAB77266.1 xref: EMBL:CAB88383.1 xref: EMBL:CAC40651.1 xref: UniProtKB:Q8N4Q6 xref: UniProtKB:Q96SD5 xref: UniProtKB:Q9NPF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017329 ! CENTA2_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001669 ! phosphatidylinositol-4,5-bisphosphate binding relationship: has_function CCO:F0001670 ! phosphatidylinositol-3,4,5-triphosphate binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_function CCO:F0005836 ! phosphatidylinositol-3,4-bisphosphate binding relationship: has_function CCO:F0005869 ! inositol 1,3,4,5 tetrakisphosphate binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020274 ! centa2-eef1g physical interaction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity [Term] id: CCO:B0058851 name: FZD3_HUMAN def: "Frizzled-3 precursor" [UniProtKB:Q9NPG1] synonym: "Fz-3" EXACT [UniProtKB:Q9NPG1] synonym: "hFz3" EXACT [UniProtKB:Q9NPG1] xref: EMBL:AAF89088.1 xref: EMBL:BAA94968.1 xref: EMBL:CAB89114.1 xref: UniProtKB:Q9NPG1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017852 ! FZD3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058852 name: UBN1_HUMAN def: "Ubinuclein" [UniProtKB:Q9NPG3] synonym: "Ubiquitously expressed nuclear protein" EXACT [UniProtKB:Q9NPG3] synonym: "VT4" EXACT [UniProtKB:Q9NPG3] xref: EMBL:AAA64188.1 xref: EMBL:AAF31755.1 xref: EMBL:AAF31756.1 xref: EMBL:AAF34869.1 xref: UniProtKB:Q13079 xref: UniProtKB:Q9NPG3 xref: UniProtKB:Q9P1P7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020400 ! UBN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0071672 ! UBN1_HUMAN-Phosphoserine173 relationship: transforms_into CCO:B0071673 ! UBN1_HUMAN-Phosphoserine175 relationship: transforms_into CCO:B0071674 ! UBN1_HUMAN-Phosphoserine493 [Term] id: CCO:B0058853 name: IL1AP_HUMAN def: "Interleukin-1 receptor accessory protein precursor" [UniProtKB:Q9NPH3] synonym: "IL-1 receptor accessory protein" EXACT [UniProtKB:Q9NPH3] synonym: "IL-1RAcP" EXACT [UniProtKB:Q9NPH3] xref: EMBL:AAB84059.1 xref: EMBL:AAC39609.1 xref: EMBL:AAF71687.1 xref: EMBL:AAF71688.1 xref: EMBL:AAF71689.1 xref: EMBL:AAH53621.1 xref: EMBL:AAO49451.1 xref: EMBL:AAQ01755.1 xref: EMBL:AAQ01756.1 xref: EMBL:AAQ01757.1 xref: EMBL:AAQ01758.1 xref: EMBL:AAQ01759.1 xref: EMBL:BAA25421.1 xref: UniProtKB:O14915 xref: UniProtKB:Q86WJ7 xref: UniProtKB:Q9NPH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018255 ! IL1RAP_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001255 ! interleukin-1 receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0018040 ! il1racp-tirp-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067072 ! IL1AP_HUMAN-Phosphothreonine395 relationship: transforms_into CCO:B0067073 ! IL1AP_HUMAN-Phosphothreonine398 [Term] id: CCO:B0058854 name: NOX4_HUMAN def: "NADPH oxidase 4" [UniProtKB:Q9NPH5] synonym: "EC 1.6.3.-" EXACT [UniProtKB:Q9NPH5] synonym: "Kidney superoxide-producing NADPH oxidase" EXACT [UniProtKB:Q9NPH5] synonym: "KOX-1" EXACT [UniProtKB:Q9NPH5] synonym: "Renal NAD(P)H-oxidase" EXACT [UniProtKB:Q9NPH5] xref: EMBL:AAF68973.1 xref: EMBL:AAF87572.1 xref: EMBL:AAH40105.1 xref: EMBL:AAH51371.1 xref: EMBL:AAP41109.1 xref: EMBL:BAA95695.1 xref: EMBL:BAF84519.1 xref: EMBL:CAG28807.1 xref: EMBL:CAG28808.1 xref: EMBL:CAG28809.1 xref: EMBL:CAG28810.1 xref: EMBL:CAG28811.1 xref: UniProtKB:A8K715 xref: UniProtKB:Q5K3R4 xref: UniProtKB:Q5K3R5 xref: UniProtKB:Q5K3R6 xref: UniProtKB:Q5K3R8 xref: UniProtKB:Q7Z7G3 xref: UniProtKB:Q86V92 xref: UniProtKB:Q9NPH5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018822 ! NOX4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003062 ! NAD(P)H oxidase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004184 ! oxygen sensor activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0058855 name: PNRC2_HUMAN def: "Proline-rich nuclear receptor coactivator 2" [UniProtKB:Q9NPJ4] xref: EMBL:AAF36128.1 xref: EMBL:AAH01959.1 xref: EMBL:AAH78177.1 xref: EMBL:AAH85018.1 xref: EMBL:AAK54613.1 xref: EMBL:BAA91082.1 xref: EMBL:CAI14802.1 xref: UniProtKB:Q9NPJ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019460 ! PNRC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058856 name: NLRC4_HUMAN def: "NLR family CARD domain-containing protein 4" [UniProtKB:Q9NPP4] synonym: "CARD, LRR, and NACHT-containing protein" EXACT [UniProtKB:Q9NPP4] synonym: "Caspase recruitment domain-containing protein 12" EXACT [UniProtKB:Q9NPP4] synonym: "Clan protein" EXACT [UniProtKB:Q9NPP4] synonym: "Ice protease-activating factor" EXACT [UniProtKB:Q9NPP4] synonym: "Ipaf" EXACT [UniProtKB:Q9NPP4] xref: EMBL:AAH31555.1 xref: EMBL:AAK14776.1 xref: EMBL:AAK14777.1 xref: EMBL:AAK14778.1 xref: EMBL:AAK14779.1 xref: EMBL:AAK38730.1 xref: EMBL:AAK53443.1 xref: EMBL:AAK59843.1 xref: EMBL:AAQ88519.1 xref: EMBL:CAB97523.1 xref: UniProtKB:Q96J81 xref: UniProtKB:Q96J82 xref: UniProtKB:Q96J83 xref: UniProtKB:Q9NPP4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018805 ! NLRC4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0058857 name: SCRT2_HUMAN def: "Transcriptional repressor scratch 2" [UniProtKB:Q9NQ03] synonym: "Scratch homolog 2 zinc finger protein" EXACT [UniProtKB:Q9NQ03] xref: EMBL:AAM98768.1 xref: EMBL:CAC00548.3 xref: UniProtKB:Q9NQ03 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019852 ! SCRT2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058858 name: SLAF7_HUMAN def: "SLAM family member 7 precursor" [UniProtKB:Q9NQ25] synonym: "CD2 subset 1" EXACT [UniProtKB:Q9NQ25] synonym: "CD2-like receptor-activating cytotoxic cells" EXACT [UniProtKB:Q9NQ25] synonym: "CD319 antigen" EXACT [UniProtKB:Q9NQ25] synonym: "CRACC" EXACT [UniProtKB:Q9NQ25] synonym: "Membrane protein FOAP-12" EXACT [UniProtKB:Q9NQ25] synonym: "Novel Ly9" EXACT [UniProtKB:Q9NQ25] synonym: "Protein 19A" EXACT [UniProtKB:Q9NQ25] xref: EMBL:AAH27867.1 xref: EMBL:AAK11549.1 xref: EMBL:AAL26989.1 xref: EMBL:AAQ88876.1 xref: EMBL:BAB61022.1 xref: EMBL:CAB76561.1 xref: EMBL:CAB81950.2 xref: EMBL:CAC00579.1 xref: EMBL:CAD39085.1 xref: EMBL:CAH73507.1 xref: EMBL:CAH73508.1 xref: UniProtKB:Q8N6Y8 xref: UniProtKB:Q8ND32 xref: UniProtKB:Q9NQ25 xref: UniProtKB:Q9NY08 xref: UniProtKB:Q9NY23 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019931 ! SLAMF7_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002050 ! natural killer cell mediated cytotoxicity [Term] id: CCO:B0058859 name: ESM1_HUMAN def: "Endothelial cell-specific molecule 1 precursor" [UniProtKB:Q9NQ30] synonym: "ESM-1" EXACT [UniProtKB:Q9NQ30] synonym: "ESM-1 secretory protein" EXACT [UniProtKB:Q9NQ30] xref: EMBL:AAH11989.1 xref: EMBL:CAA61597.1 xref: EMBL:CAB94771.1 xref: UniProtKB:Q15330 xref: UniProtKB:Q96ES3 xref: UniProtKB:Q9NQ30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017729 ! ESM1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0058860 name: ASCL3_HUMAN def: "Achaete-scute homolog 3" [UniProtKB:Q9NQ33] synonym: "bHLH transcriptional regulator Sgn-1" EXACT [UniProtKB:Q9NQ33] xref: EMBL:BAB83913.1 xref: EMBL:CAB92288.1 xref: UniProtKB:Q8WYQ6 xref: UniProtKB:Q9NQ33 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017077 ! ASCL3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058861 name: TMM9B_HUMAN def: "Transmembrane protein 9B precursor" [UniProtKB:Q9NQ34] xref: EMBL:AAH40124.1 xref: EMBL:AAQ89428.1 xref: EMBL:CAB92287.1 xref: UniProtKB:Q9NQ34 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020292 ! TMEM9B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020539 ! ddx24-c11orf15 physical interaction relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058862 name: ISK5_HUMAN def: "Serine protease inhibitor Kazal-type 5 precursor" [UniProtKB:Q9NQ38] synonym: "LEKTI" EXACT [UniProtKB:Q9NQ38] synonym: "Lympho-epithelial Kazal-type-related inhibitor" EXACT [UniProtKB:Q9NQ38] xref: EMBL:AAK97139.1 xref: EMBL:AAK97140.1 xref: EMBL:CAB40839.1 xref: EMBL:CAB96877.1 xref: UniProtKB:O75770 xref: UniProtKB:Q96PP2 xref: UniProtKB:Q96PP3 xref: UniProtKB:Q9NQ38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018325 ! SPINK5_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0001664 ! lamellar body relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0002394 ! regulation of T cell differentiation [Term] id: CCO:B0058863 name: LHX9_HUMAN def: "LIM/homeobox protein Lhx9" [UniProtKB:Q9NQ69] synonym: "LIM homeobox protein 9" EXACT [UniProtKB:Q9NQ69] xref: EMBL:CAB97493.1 xref: EMBL:CAB98128.1 xref: EMBL:CAC33174.1 xref: EMBL:CAH71760.1 xref: UniProtKB:Q5VUE3 xref: UniProtKB:Q9BYU6 xref: UniProtKB:Q9NQ69 xref: UniProtKB:Q9NQ70 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018491 ! LHX9_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058864 name: GPC5C_HUMAN def: "G-protein coupled receptor family C group 5 member C precursor" [UniProtKB:Q9NQ84] synonym: "RAIG-3" EXACT [UniProtKB:Q9NQ84] synonym: "Retinoic acid-induced gene 3 protein" EXACT [UniProtKB:Q9NQ84] xref: EMBL:AAF72870.1 xref: EMBL:AAH16860.2 xref: EMBL:AAP36103.1 xref: EMBL:BAC11595.1 xref: EMBL:CAC00633.1 xref: UniProtKB:Q9NQ84 xref: UniProtKB:Q9NZG5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017997 ! GPRC5C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018452 ! bat5-gprc5c physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0066538 ! GPC5C_HUMAN-Phosphotyrosine324 relationship: transforms_into CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 [Term] id: CCO:B0058865 name: HEYL_HUMAN def: "Hairy/enhancer-of-split related with YRPW motif-like protein" [UniProtKB:Q9NQ87] synonym: "Hairy-related transcription factor 3" EXACT [UniProtKB:Q9NQ87] synonym: "hHeyL" EXACT [UniProtKB:Q9NQ87] synonym: "hHRT3" EXACT [UniProtKB:Q9NQ87] xref: EMBL:AAG31158.1 xref: EMBL:AAH06087.1 xref: EMBL:CAB75716.1 xref: EMBL:CAI19572.1 xref: UniProtKB:Q5TG99 xref: UniProtKB:Q9NQ87 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018128 ! HEYL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015683 ! heyl-rbpms physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058866 name: A1CF_HUMAN def: "APOBEC1 complementation factor" [UniProtKB:Q9NQ94] synonym: "APOBEC1-stimulating protein" EXACT [UniProtKB:Q9NQ94] xref: EMBL:AAF34824.1 xref: EMBL:AAF76221.1 xref: EMBL:AAF76222.1 xref: EMBL:BAA91086.1 xref: EMBL:CAB94754.1 xref: EMBL:CAB94755.1 xref: EMBL:CAI14233.1 xref: EMBL:CAI14235.1 xref: EMBL:CAI14236.1 xref: EMBL:CAI15762.1 xref: EMBL:CAI15763.1 xref: EMBL:CAI15764.1 xref: UniProtKB:Q5SZQ0 xref: UniProtKB:Q9NQ93 xref: UniProtKB:Q9NQ94 xref: UniProtKB:Q9NQX8 xref: UniProtKB:Q9NQX9 xref: UniProtKB:Q9NXC9 xref: UniProtKB:Q9NZD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016860 ! A1CF_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0001073 ! apolipoprotein B mRNA editing enzyme complex relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0058867 name: HPS4_HUMAN def: "Hermansky-Pudlak syndrome 4 protein" [UniProtKB:Q9NQG7] synonym: "Light-ear protein homolog" EXACT [UniProtKB:Q9NQG7] xref: EMBL:AAK95330.1 xref: EMBL:BAB33337.1 xref: EMBL:BAB71540.1 xref: EMBL:CAB97208.1 xref: EMBL:CAD28549.1 xref: EMBL:CAI17880.1 xref: UniProtKB:Q5H8V6 xref: UniProtKB:Q96LX6 xref: UniProtKB:Q9BY93 xref: UniProtKB:Q9NQG7 xref: UniProtKB:Q9UH37 xref: UniProtKB:Q9UH38 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018157 ! HPS4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015952 ! hsp1-hsp4-11 physical interaction relationship: participates_in CCO:I0015953 ! hsp1-hsp4-12 physical interaction relationship: participates_in CCO:I0016126 ! hsp1-hsp4-1 physical interaction relationship: participates_in CCO:I0016127 ! hsp1-hsp4-2 physical interaction relationship: participates_in CCO:I0016128 ! hsp1-hsp4-14 physical interaction relationship: participates_in CCO:I0017381 ! hsp1-hsp4-3 physical interaction relationship: participates_in CCO:I0017382 ! hsp1-hsp4-4 physical interaction relationship: participates_in CCO:I0017515 ! hsp1-hsp4-9 physical interaction relationship: participates_in CCO:I0018200 ! hsp1-hsp4-8 physical interaction relationship: participates_in CCO:I0018201 ! hsp1-hsp4-10 physical interaction relationship: participates_in CCO:I0018202 ! hsp1-hsp4-15 physical interaction relationship: participates_in CCO:I0018666 ! hsp1-hsp4-7 physical interaction relationship: participates_in CCO:I0018668 ! hsp1-hsp4-13 physical interaction relationship: participates_in CCO:I0019501 ! hsp1-hsp4-5 physical interaction relationship: participates_in CCO:I0019502 ! hsp1-hsp4-6 physical interaction relationship: participates_in CCO:P0002964 ! protein stabilization relationship: transforms_into CCO:B0066894 ! HPS4_HUMAN-Phosphoserine355 [Term] id: CCO:B0058868 name: DMRT3_HUMAN def: "Doublesex- and mab-3-related transcription factor 3" [UniProtKB:Q9NQL9] xref: EMBL:AAF78892.1 xref: EMBL:AAI13585.1 xref: EMBL:AAI17246.1 xref: EMBL:CAB99336.1 xref: EMBL:CAC37947.1 xref: UniProtKB:Q7LA03 xref: UniProtKB:Q7LCH8 xref: UniProtKB:Q96SC7 xref: UniProtKB:Q9NQL9 xref: UniProtKB:Q9NRQ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017589 ! DMRT3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058869 name: OR2S1_HUMAN def: "Olfactory receptor 2S2" [UniProtKB:Q9NQN1] synonym: "Olfactory receptor OR9-3" EXACT [UniProtKB:Q9NQN1] xref: EMBL:AAI04870.1 xref: EMBL:AAI13652.1 xref: EMBL:AAK95086.1 xref: EMBL:CAB96728.2 xref: EMBL:DAA04841.1 xref: UniProtKB:Q2M3L0 xref: UniProtKB:Q6IF19 xref: UniProtKB:Q96R42 xref: UniProtKB:Q9NQN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019114 ! OR2S2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058870 name: Q9NQR6_HUMAN def: "DMRT2/terra-like protein" [UniProtKB:Q9NQR6] xref: EMBL:AAF86295.1 xref: UniProtKB:Q9NQR6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017588 ! DMRT2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058871 name: AVEN_HUMAN def: "Cell death regulator Aven" [UniProtKB:Q9NQS1] xref: EMBL:AAF91470.1 xref: EMBL:AAH10488.1 xref: EMBL:AAH63533.1 xref: UniProtKB:Q9NQS1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017104 ! AVEN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0063685 ! AVEN_HUMAN-Phosphoserine94 [Term] id: CCO:B0058872 name: GPR84_HUMAN def: "Probable G-protein coupled receptor 84" [UniProtKB:Q9NQS5] synonym: "Inflammation-related G-protein coupled receptor EX33" EXACT [UniProtKB:Q9NQS5] xref: EMBL:AAF91467.1 xref: EMBL:AAH20614.1 xref: EMBL:AAK01857.1 xref: EMBL:BAB89299.1 xref: UniProtKB:Q9NQS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018036 ! GPR84_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058873 name: PRD10_HUMAN def: "PR domain zinc finger protein 10" [UniProtKB:Q9NQV6] synonym: "PR domain-containing protein 10" EXACT [UniProtKB:Q9NQV6] synonym: "Tristanin" EXACT [UniProtKB:Q9NQV6] xref: EMBL:AAF87243.1 xref: EMBL:AAP30847.1 xref: EMBL:BAA86545.2 xref: UniProtKB:Q863Z2 xref: UniProtKB:Q9NQV6 xref: UniProtKB:Q9ULI9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019487 ! PRDM10_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069487 ! PRD10_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0069488 ! PRD10_HUMAN-Phosphothreonine342 relationship: transforms_into CCO:B0069489 ! PRD10_HUMAN-Phosphoserine1002 [Term] id: CCO:B0058874 name: PRDM9_HUMAN def: "PR domain zinc finger protein 9" [UniProtKB:Q9NQV7] synonym: "PR domain-containing protein 9" EXACT [UniProtKB:Q9NQV7] xref: EMBL:AAF87242.1 xref: EMBL:ABD47939.1 xref: UniProtKB:Q27Q50 xref: UniProtKB:Q9NQV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019500 ! PRDM9_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058875 name: PRDM8_HUMAN def: "PR domain zinc finger protein 8" [UniProtKB:Q9NQV8] synonym: "PR domain-containing protein 8" EXACT [UniProtKB:Q9NQV8] xref: EMBL:AAF87241.1 xref: EMBL:AAH71584.1 xref: EMBL:BAF84826.1 xref: EMBL:EAX05851.1 xref: UniProtKB:A8K7X2 xref: UniProtKB:Q6IQ36 xref: UniProtKB:Q9NQV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019499 ! PRDM8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058876 name: PRDM7_HUMAN def: "PR domain zinc finger protein 7" [UniProtKB:Q9NQW5] synonym: "PR domain-containing protein 7" EXACT [UniProtKB:Q9NQW5] xref: EMBL:AAF78084.1 xref: EMBL:AAF78085.1 xref: UniProtKB:Q9NQW4 xref: UniProtKB:Q9NQW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019498 ! PRDM7_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058877 name: CNGB3_HUMAN def: "Cyclic nucleotide-gated cation channel beta-3" [UniProtKB:Q9NQW8] synonym: "CNG channel beta-3" EXACT [UniProtKB:Q9NQW8] synonym: "Cone photoreceptor cGMP-gated channel subunit beta" EXACT [UniProtKB:Q9NQW8] synonym: "Cyclic nucleotide-gated cation channel modulatory subunit" EXACT [UniProtKB:Q9NQW8] synonym: "Cyclic nucleotide-gated channel beta-3" EXACT [UniProtKB:Q9NQW8] xref: EMBL:AAF80179.1 xref: EMBL:AAF86274.1 xref: UniProtKB:Q9NQW8 xref: UniProtKB:Q9NRE9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017400 ! CNGB3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001499 ! intracellular cGMP activated cation channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000185 ! photoreceptor outer segment relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058878 name: PRDM6_HUMAN def: "PR domain zinc finger protein 6" [UniProtKB:Q9NQX0] synonym: "PR domain-containing protein 6" EXACT [UniProtKB:Q9NQX0] xref: EMBL:AAF78078.1 xref: EMBL:AAF78079.1 xref: UniProtKB:Q9NQW9 xref: UniProtKB:Q9NQX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019497 ! PRDM6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0003048 ! negative regulation of smooth muscle cell differentiation [Term] id: CCO:B0058879 name: PRDM5_HUMAN def: "PR domain zinc finger protein 5" [UniProtKB:Q9NQX1] synonym: "PR domain-containing protein 5" EXACT [UniProtKB:Q9NQX1] xref: EMBL:AAF78077.1 xref: EMBL:AAH66942.1 xref: EMBL:AAI21038.1 xref: EMBL:BAG51686.1 xref: UniProtKB:Q0VAJ0 xref: UniProtKB:Q6NXQ7 xref: UniProtKB:Q9NQX1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019496 ! PRDM5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058880 name: ZN331_HUMAN def: "Zinc finger protein 331" [UniProtKB:Q9NQX6] synonym: "C2H2-like zinc finger protein rearranged in thyroid adenomas" EXACT [UniProtKB:Q9NQX6] synonym: "Zinc finger protein 463" EXACT [UniProtKB:Q9NQX6] xref: EMBL:AAF70179.2 xref: EMBL:AAF78075.1 xref: EMBL:AAH09433.1 xref: UniProtKB:Q96GJ4 xref: UniProtKB:Q9NQX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020707 ! ZNF331_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058881 name: ZNF71_HUMAN def: "Endothelial zinc finger protein induced by tumor necrosis factor alpha" [UniProtKB:Q9NQZ8] synonym: "Zinc finger protein 71" EXACT [UniProtKB:Q9NQZ8] xref: EMBL:AAA61315.1 xref: EMBL:AAD23608.1 xref: EMBL:AAF88036.1 xref: EMBL:AAH14280.1 xref: EMBL:CAC16174.1 xref: UniProtKB:Q15919 xref: UniProtKB:Q9NQZ8 xref: UniProtKB:Q9UC09 xref: UniProtKB:Q9UQD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020982 ! ZNF71_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058882 name: ZN302_HUMAN def: "Zinc finger protein 302" [UniProtKB:Q9NR11] synonym: "ZNF135-like" EXACT [UniProtKB:Q9NR11] synonym: "ZNF140-like" EXACT [UniProtKB:Q9NR11] xref: EMBL:AAF67475.1 xref: EMBL:AAF74775.1 xref: EMBL:AAH24176.1 xref: EMBL:AAK11224.1 xref: UniProtKB:Q9BZD8 xref: UniProtKB:Q9NR11 xref: UniProtKB:Q9P0J4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020697 ! ZNF302_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058883 name: Q9NR26_HUMAN def: "CD164" [UniProtKB:Q9NR26] synonym: "CD164 antigen, sialomucin, isoform CRA_a" EXACT [UniProtKB:Q9NR26] synonym: "CD164 molecule, sialomucin" EXACT [UniProtKB:Q9NR26] synonym: "cDNA, FLJ92676, Homo sapiens CD164 antigen, sialomucin (CD164), mRNA" EXACT [UniProtKB:Q9NR26] xref: EMBL:AAF85965.1 xref: EMBL:AAG53903.1 xref: EMBL:AAG53906.1 xref: EMBL:AAH11522.1 xref: EMBL:BAG35275.1 xref: EMBL:CAI40704.1 xref: EMBL:EAW48348.1 xref: UniProtKB:Q9NR26 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018683 ! CD164_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: participates_in CCO:P0000707 ! negative regulation of cell adhesion relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0058884 name: DBLOH_HUMAN def: "Diablo homolog, mitochondrial precursor" [UniProtKB:Q9NR28] synonym: "Direct IAP-binding protein with low pI" EXACT [UniProtKB:Q9NR28] synonym: "Second mitochondria-derived activator of caspase" EXACT [UniProtKB:Q9NR28] synonym: "Smac protein" EXACT [UniProtKB:Q9NR28] xref: EMBL:AAF87716.1 xref: EMBL:AAG22077.1 xref: EMBL:AAH04417.1 xref: EMBL:AAH11909.1 xref: EMBL:BAB14994.1 xref: EMBL:BAB71568.1 xref: UniProtKB:Q96LV0 xref: UniProtKB:Q9BT11 xref: UniProtKB:Q9HAV6 xref: UniProtKB:Q9NR28 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017525 ! DIABLO_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0017874 ! birc7-diablo-4 physical interaction relationship: participates_in CCO:I0017876 ! birc4-diablo-5 physical interaction relationship: participates_in CCO:I0018028 ! birc7-diablo-3 physical interaction relationship: participates_in CCO:I0018031 ! birc4-diablo-4 physical interaction relationship: participates_in CCO:I0018179 ! birc4-diablo-1 physical interaction relationship: participates_in CCO:I0018185 ! birc7-diablo-2 physical interaction relationship: participates_in CCO:I0018188 ! birc7-diablo-6 physical interaction relationship: participates_in CCO:I0018377 ! birc2-diablo-1 physical interaction relationship: participates_in CCO:I0018378 ! birc4-diablo-6 physical interaction relationship: participates_in CCO:I0018380 ! birc2-diablo-2 physical interaction relationship: participates_in CCO:I0018619 ! mihb-diablo physical interaction relationship: participates_in CCO:I0018620 ! mihc-diablo physical interaction relationship: participates_in CCO:I0019246 ! birc7-diablo-7 physical interaction relationship: participates_in CCO:I0019247 ! birc4-diablo-2 physical interaction relationship: participates_in CCO:I0019301 ! birc2-traf2-3 physical interaction relationship: participates_in CCO:I0019302 ! birc3-traf2-2 physical interaction relationship: participates_in CCO:I0019361 ! birc7-diablo-8 physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000832 ! induction of apoptosis via death domain receptors relationship: participates_in CCO:P0000842 ! caspase activation via cytochrome c [Term] id: CCO:B0058885 name: SAR1A_HUMAN def: "GTP-binding protein SAR1a" [UniProtKB:Q9NR31] synonym: "COPII-associated small GTPase" EXACT [UniProtKB:Q9NR31] xref: EMBL:AAF81741.1 xref: EMBL:AAG16638.1 xref: EMBL:AAH03658.1 xref: EMBL:CAB66658.1 xref: UniProtKB:Q9NR31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019837 ! SAR1A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0070318 ! SAR1A_HUMAN-Phosphothreonine139 [Term] id: CCO:B0058886 name: ASH1L_HUMAN def: "Probable histone-lysine N-methyltransferase ASH1L" [UniProtKB:Q9NR48] synonym: "Absent small and homeotic disks protein 1 homolog" EXACT [UniProtKB:Q9NR48] synonym: "ASH1-like protein" EXACT [UniProtKB:Q9NR48] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9NR48] synonym: "huASH1" EXACT [UniProtKB:Q9NR48] synonym: "Lysine N-methyltransferase 2H" EXACT [UniProtKB:Q9NR48] xref: EMBL:AAF68983.1 xref: EMBL:BAA92658.1 xref: EMBL:BAD92305.1 xref: EMBL:CAI12716.2 xref: EMBL:CAI12722.1 xref: EMBL:CAI13211.2 xref: EMBL:CAI13212.1 xref: UniProtKB:Q59GP1 xref: UniProtKB:Q5T714 xref: UniProtKB:Q5T715 xref: UniProtKB:Q9NR48 xref: UniProtKB:Q9P2C7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017082 ! ASH1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063628 ! ASH1L_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0063629 ! ASH1L_HUMAN-Phosphoserine1681 [Term] id: CCO:B0058887 name: BATF3_HUMAN def: "Basic leucine zipper transcriptional factor ATF-like 3" [UniProtKB:Q9NR55] synonym: "21 kDa small nuclear factor isolated from T-cells" EXACT [UniProtKB:Q9NR55] synonym: "B-ATF-3" EXACT [UniProtKB:Q9NR55] synonym: "Jun dimerization protein p21SNFT" EXACT [UniProtKB:Q9NR55] xref: EMBL:AAF73966.1 xref: EMBL:AAI17490.1 xref: EMBL:AAI17492.1 xref: EMBL:CAI17048.1 xref: EMBL:EAW93381.1 xref: UniProtKB:Q9NR55 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017130 ! BATF3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058888 name: ASAH2_HUMAN def: "Neutral ceramidase" [UniProtKB:Q9NR71] synonym: "Acylsphingosine deacylase 2" EXACT [UniProtKB:Q9NR71] synonym: "BCDase" EXACT [UniProtKB:Q9NR71] synonym: "EC 3.5.1.23" EXACT [UniProtKB:Q9NR71] synonym: "hCD" EXACT [UniProtKB:Q9NR71] synonym: "LCDase" EXACT [UniProtKB:Q9NR71] synonym: "N-acylsphingosine amidohydrolase 2" EXACT [UniProtKB:Q9NR71] synonym: "N-CDase" EXACT [UniProtKB:Q9NR71] synonym: "NCDase" EXACT [UniProtKB:Q9NR71] synonym: "Non-lysosomal ceramidase" EXACT [UniProtKB:Q9NR71] xref: EMBL:AAF86240.1 xref: EMBL:AAI07106.1 xref: EMBL:AAL06061.1 xref: EMBL:AAQ04667.2 xref: EMBL:CAI15766.1 xref: EMBL:CAI15767.1 xref: EMBL:CAI15870.1 xref: EMBL:CAI17190.1 xref: UniProtKB:Q3KNU1 xref: UniProtKB:Q5SNT7 xref: UniProtKB:Q5SZP6 xref: UniProtKB:Q5SZP7 xref: UniProtKB:Q5T1D5 xref: UniProtKB:Q71ME6 xref: UniProtKB:Q9NR71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017056 ! ASAH2_human relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003524 ! ceramidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058889 name: ARHG3_HUMAN def: "Rho guanine nucleotide exchange factor 3" [UniProtKB:Q9NR81] synonym: "Exchange factor found in platelets and leukemic and neuronal tissues" EXACT [UniProtKB:Q9NR81] synonym: "XPLN" EXACT [UniProtKB:Q9NR81] xref: EMBL:AAF79954.1 xref: EMBL:AAH54345.2 xref: EMBL:AAH68513.1 xref: EMBL:AAH98122.2 xref: EMBL:AAH98272.2 xref: EMBL:AAH99715.1 xref: EMBL:AAI04724.2 xref: EMBL:AAP97313.1 xref: EMBL:BAB14891.1 xref: EMBL:BAD92898.1 xref: EMBL:CAB66766.1 xref: UniProtKB:Q4FZB6 xref: UniProtKB:Q4QQI5 xref: UniProtKB:Q4QQQ0 xref: UniProtKB:Q59F00 xref: UniProtKB:Q6NUN3 xref: UniProtKB:Q7Z4U2 xref: UniProtKB:Q7Z5T2 xref: UniProtKB:Q9H7T4 xref: UniProtKB:Q9NR81 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017014 ! ARHGEF3_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000783 ! Rho protein signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0058890 name: S2A4R_HUMAN def: "SLC2A4 regulator" [UniProtKB:Q9NR83] synonym: "GEF" EXACT [UniProtKB:Q9NR83] synonym: "GLUT4 enhancer factor" EXACT [UniProtKB:Q9NR83] synonym: "HDBP-1" EXACT [UniProtKB:Q9NR83] synonym: "Huntington disease gene regulatory region-binding protein 1" EXACT [UniProtKB:Q9NR83] xref: EMBL:AAF97516.2 xref: EMBL:AAH01402.2 xref: EMBL:AAH17446.1 xref: EMBL:AAH28349.2 xref: EMBL:AAH52306.1 xref: EMBL:BAD29732.1 xref: EMBL:BAD29733.1 xref: EMBL:CAC44024.1 xref: UniProtKB:Q6F6I6 xref: UniProtKB:Q6F6I7 xref: UniProtKB:Q6GTK5 xref: UniProtKB:Q8TAH5 xref: UniProtKB:Q8WVW7 xref: UniProtKB:Q96QD3 xref: UniProtKB:Q9BV85 xref: UniProtKB:Q9NR83 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019823 ! SLC2A4RG_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058891 name: TLR9_HUMAN def: "Toll-like receptor 9 precursor" [UniProtKB:Q9NR96] synonym: "CD289 antigen" EXACT [UniProtKB:Q9NR96] xref: EMBL:AAF72189.1 xref: EMBL:AAF72190.1 xref: EMBL:AAF78037.1 xref: EMBL:AAG01734.1 xref: EMBL:AAG01735.1 xref: EMBL:AAG01736.1 xref: EMBL:AAH32713.1 xref: EMBL:AAQ89443.1 xref: EMBL:BAB19259.1 xref: UniProtKB:Q6UVZ2 xref: UniProtKB:Q9HD68 xref: UniProtKB:Q9HD69 xref: UniProtKB:Q9HD70 xref: UniProtKB:Q9NR96 xref: UniProtKB:Q9NYC2 xref: UniProtKB:Q9NYC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020284 ! TLR9_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005568 ! siRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002297 ! positive regulation of interferon-alpha biosynthetic process relationship: participates_in CCO:P0002300 ! positive regulation of interferon-beta biosynthetic process [Term] id: CCO:B0058892 name: TLR8_HUMAN def: "Toll-like receptor 8 precursor" [UniProtKB:Q9NR97] synonym: "CD288 antigen" EXACT [UniProtKB:Q9NR97] xref: EMBL:AAF64061.1 xref: EMBL:AAF78036.1 xref: EMBL:AAI01077.1 xref: EMBL:AAI01078.1 xref: EMBL:AAQ88663.1 xref: UniProtKB:Q495P4 xref: UniProtKB:Q6UXL6 xref: UniProtKB:Q9NR97 xref: UniProtKB:Q9NYG9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020283 ! TLR8_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001423 ! Toll binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002297 ! positive regulation of interferon-alpha biosynthetic process relationship: participates_in CCO:P0002300 ! positive regulation of interferon-beta biosynthetic process relationship: participates_in CCO:P0002357 ! positive regulation of interleukin-8 biosynthetic process [Term] id: CCO:B0058893 name: Q9NRB8_HUMAN def: "G-protein coupled receptor EDG-7" [UniProtKB:Q9NRB8] xref: EMBL:AAF91291.1 xref: UniProtKB:Q9NRB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058894 name: SPTN5_HUMAN def: "Spectrin beta chain, brain 4" [UniProtKB:Q9NRC6] synonym: "Beta-V spectrin" EXACT [UniProtKB:Q9NRC6] synonym: "BSPECV" EXACT [UniProtKB:Q9NRC6] synonym: "Spectrin, non-erythroid beta chain 4" EXACT [UniProtKB:Q9NRC6] xref: EMBL:AAF65317.1 xref: UniProtKB:Q9NRC6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020027 ! SPTBN5_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000529 ! spectrin relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0003005 ! barbed-end actin filament capping [Term] id: CCO:B0058895 name: SIRT7_HUMAN def: "NAD-dependent deacetylase sirtuin-7" [UniProtKB:Q9NRC8] synonym: "EC 3.5.1.-" EXACT [UniProtKB:Q9NRC8] synonym: "SIR2-like protein 7" EXACT [UniProtKB:Q9NRC8] xref: EMBL:AAF43431.1 xref: EMBL:AAH17305.1 xref: EMBL:AAI01792.1 xref: EMBL:AAI01794.1 xref: EMBL:BAA92044.1 xref: EMBL:CAB70848.2 xref: UniProtKB:Q3MIK4 xref: UniProtKB:Q9NRC8 xref: UniProtKB:Q9NSZ6 xref: UniProtKB:Q9NUS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019917 ! SIRT7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020063 ! maged1-sirt7 physical interaction relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058896 name: DUOX2_HUMAN def: "Dual oxidase 2 precursor" [UniProtKB:Q9NRD8] synonym: "EC 1.11.1.-" EXACT [UniProtKB:Q9NRD8] synonym: "EC 1.6.3.1" EXACT [UniProtKB:Q9NRD8] synonym: "Large NOX 2" EXACT [UniProtKB:Q9NRD8] synonym: "Long NOX 2" EXACT [UniProtKB:Q9NRD8] synonym: "NADH/NADPH thyroid oxidase p138-tox" EXACT [UniProtKB:Q9NRD8] synonym: "NADPH oxidase/peroxidase DUOX2" EXACT [UniProtKB:Q9NRD8] synonym: "NADPH thyroid oxidase 2" EXACT [UniProtKB:Q9NRD8] synonym: "p138 thyroid oxidase" EXACT [UniProtKB:Q9NRD8] synonym: "Thyroid oxidase 2" EXACT [UniProtKB:Q9NRD8] xref: EMBL:AAF20055.1 xref: EMBL:AAF73922.1 xref: EMBL:AAF78954.1 xref: UniProtKB:A8MQ13 xref: UniProtKB:Q9NR02 xref: UniProtKB:Q9NRD8 xref: UniProtKB:Q9UHF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017631 ! DUOX2_human relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003062 ! NAD(P)H oxidase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0058897 name: DUOX1_HUMAN def: "Dual oxidase 1 precursor" [UniProtKB:Q9NRD9] synonym: "EC 1.11.1.-" EXACT [UniProtKB:Q9NRD9] synonym: "EC 1.6.3.1" EXACT [UniProtKB:Q9NRD9] synonym: "Large NOX 1" EXACT [UniProtKB:Q9NRD9] synonym: "Long NOX 1" EXACT [UniProtKB:Q9NRD9] synonym: "NADPH thyroid oxidase 1" EXACT [UniProtKB:Q9NRD9] synonym: "Thyroid oxidase 1" EXACT [UniProtKB:Q9NRD9] xref: EMBL:AAF71295.1 xref: EMBL:AAF73921.1 xref: EMBL:AAI14629.1 xref: EMBL:BAC87516.1 xref: EMBL:BAD18816.1 xref: UniProtKB:A6NH28 xref: UniProtKB:Q14C94 xref: UniProtKB:Q6ZMB3 xref: UniProtKB:Q6ZR09 xref: UniProtKB:Q9NRD9 xref: UniProtKB:Q9NZC1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017630 ! DUOX1_human relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003062 ! NAD(P)H oxidase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_function CCO:F0007987 ! NADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:B0058898 name: TSH2_HUMAN def: "Teashirt homolog 2" [UniProtKB:Q9NRE2] synonym: "Ovarian cancer-related protein 10-2" EXACT [UniProtKB:Q9NRE2] synonym: "OVC10-2" EXACT [UniProtKB:Q9NRE2] synonym: "Zinc finger protein 218" EXACT [UniProtKB:Q9NRE2] xref: EMBL:AAF76850.1 xref: EMBL:BAC03610.1 xref: EMBL:CAE45871.1 xref: EMBL:CAI95385.1 xref: EMBL:CAI95730.1 xref: UniProtKB:Q4VXM4 xref: UniProtKB:Q6N003 xref: UniProtKB:Q8N260 xref: UniProtKB:Q9NRE2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008447 ! TSHZ2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058899 name: SH2B1_HUMAN def: "SH2B adapter protein 1" [UniProtKB:Q9NRF2] synonym: "Pro-rich, PH and SH2 domain-containing signaling mediator" EXACT [UniProtKB:Q9NRF2] synonym: "PSM" EXACT [UniProtKB:Q9NRF2] synonym: "SH2 domain-containing protein 1B" EXACT [UniProtKB:Q9NRF2] xref: EMBL:AAF73912.1 xref: EMBL:AAF73913.1 xref: EMBL:AAF73914.1 xref: EMBL:AAH10704.1 xref: EMBL:BAA92537.1 xref: EMBL:BAB55148.1 xref: EMBL:BAF83021.1 xref: EMBL:CAB43208.1 xref: EMBL:CAD28530.1 xref: UniProtKB:A8K2R7 xref: UniProtKB:Q96FK3 xref: UniProtKB:Q96SX3 xref: UniProtKB:Q9NRF1 xref: UniProtKB:Q9NRF2 xref: UniProtKB:Q9NRF3 xref: UniProtKB:Q9P2P7 xref: UniProtKB:Q9Y3Y3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019886 ! SH2B1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0070463 ! SH2B1_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0070464 ! SH2B1_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0070465 ! SH2B1_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0070466 ! SH2B1_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0070467 ! SH2B1_HUMAN-Phosphotyrosine439 relationship: transforms_into CCO:B0070468 ! SH2B1_HUMAN-Phosphotyrosine494 [Term] id: CCO:B0058900 name: TULP4_HUMAN def: "Tubby-related protein 4" [UniProtKB:Q9NRJ4] synonym: "Tubby superfamily protein" EXACT [UniProtKB:Q9NRJ4] synonym: "Tubby-like protein 4" EXACT [UniProtKB:Q9NRJ4] xref: EMBL:AAF87975.1 xref: EMBL:AAG01020.1 xref: EMBL:BAA92635.1 xref: EMBL:CAI16559.1 xref: EMBL:CAI20993.1 xref: EMBL:EAW47662.1 xref: UniProtKB:Q5T3M3 xref: UniProtKB:Q9HD22 xref: UniProtKB:Q9NRJ4 xref: UniProtKB:Q9P2F0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020383 ! TULP4_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058901 name: BAZ1A_HUMAN def: "Bromodomain adjacent to zinc finger domain protein 1A" [UniProtKB:Q9NRL2] synonym: "ATP-dependent chromatin-remodeling protein" EXACT [UniProtKB:Q9NRL2] synonym: "ATP-utilizing chromatin assembly and remodeling factor 1" EXACT [UniProtKB:Q9NRL2] synonym: "CHRAC subunit ACF1" EXACT [UniProtKB:Q9NRL2] synonym: "hACF1" EXACT [UniProtKB:Q9NRL2] synonym: "hWALp1" EXACT [UniProtKB:Q9NRL2] synonym: "WCRF180" EXACT [UniProtKB:Q9NRL2] synonym: "Williams syndrome transcription factor-related chromatin-remodeling factor 180" EXACT [UniProtKB:Q9NRL2] xref: EMBL:AAF28995.1 xref: EMBL:AAF32366.1 xref: EMBL:AAF70601.1 xref: EMBL:BAA89209.1 xref: EMBL:CAB43261.1 xref: UniProtKB:Q9NRL2 xref: UniProtKB:Q9NZ15 xref: UniProtKB:Q9P065 xref: UniProtKB:Q9UIG1 xref: UniProtKB:Q9Y3V3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017131 ! BAZ1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018542 ! baz1a-baz1b-1 physical interaction relationship: participates_in CCO:I0019447 ! baz1b-smarca5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063743 ! BAZ1A_HUMAN-Phosphotyrosine606 relationship: transforms_into CCO:B0063744 ! BAZ1A_HUMAN-Phosphoserine1339 relationship: transforms_into CCO:B0063745 ! BAZ1A_HUMAN-Phosphoserine1353 relationship: transforms_into CCO:B0063746 ! BAZ1A_HUMAN-Phosphoserine1363 relationship: transforms_into CCO:B0063747 ! BAZ1A_HUMAN-Phosphothreonine1367 relationship: transforms_into CCO:B0063748 ! BAZ1A_HUMAN-Phosphoserine1371 relationship: transforms_into CCO:B0063749 ! BAZ1A_HUMAN-Phosphoserine1402 relationship: transforms_into CCO:B0063750 ! BAZ1A_HUMAN-Phosphoserine1413 relationship: transforms_into CCO:B0063751 ! BAZ1A_HUMAN-Phosphoserine1417 relationship: transforms_into CCO:B0063752 ! BAZ1A_HUMAN-Phosphothreonine1547 [Term] id: CCO:B0058902 name: CYTL1_HUMAN def: "Cytokine-like protein 1 precursor" [UniProtKB:Q9NRR1] synonym: "Protein C17" EXACT [UniProtKB:Q9NRR1] xref: EMBL:AAF73372.1 xref: EMBL:AAH31391.1 xref: EMBL:AAQ89459.1 xref: UniProtKB:Q9NRR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017514 ! CYTL1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058903 name: C42S2_HUMAN def: "CDC42 small effector protein 2" [UniProtKB:Q9NRR3] synonym: "Small effector of CDC42 protein 2" EXACT [UniProtKB:Q9NRR3] xref: EMBL:AAF87598.1 xref: EMBL:AAH96703.1 xref: EMBL:AAH96738.1 xref: EMBL:AAH98349.1 xref: EMBL:EAW62373.1 xref: UniProtKB:Q4KMT9 xref: UniProtKB:Q9NRR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017198 ! CDC42SE2_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:B0058904 name: C42S1_HUMAN def: "CDC42 small effector protein 1" [UniProtKB:Q9NRR8] synonym: "CDC42-binding protein SCIP1" EXACT [UniProtKB:Q9NRR8] synonym: "Small effector of CDC42 protein 1" EXACT [UniProtKB:Q9NRR8] xref: EMBL:AAF87597.1 xref: EMBL:AAF97248.1 xref: EMBL:AAG17723.1 xref: EMBL:AAH12796.2 xref: EMBL:AAH41604.1 xref: EMBL:CAI13349.1 xref: EMBL:EAW53477.1 xref: UniProtKB:Q9HB17 xref: UniProtKB:Q9NQR2 xref: UniProtKB:Q9NRR8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017197 ! CDC42SE1_human relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape [Term] id: CCO:B0058905 name: RAB6B_HUMAN def: "Ras-related protein Rab-6B" [UniProtKB:Q9NRW1] xref: EMBL:AAF61637.1 xref: EMBL:AAH02510.1 xref: EMBL:AAM21088.1 xref: EMBL:AAP35927.1 xref: UniProtKB:Q9NRW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019603 ! RAB6B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069693 ! RAB6B_HUMAN-Cysteine methyl ester208 [Term] id: CCO:B0058906 name: DUS22_HUMAN def: "Dual specificity protein phosphatase 22" [UniProtKB:Q9NRW4] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9NRW4] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9NRW4] synonym: "JNK-stimulatory phosphatase-1" EXACT [UniProtKB:Q9NRW4] synonym: "JSP-1" EXACT [UniProtKB:Q9NRW4] synonym: "LMW-DSP2" EXACT [UniProtKB:Q9NRW4] synonym: "Mitogen-activated protein kinase phosphatase x" EXACT [UniProtKB:Q9NRW4] xref: EMBL:AAF86649.1 xref: EMBL:AAH16844.1 xref: EMBL:AAH22847.1 xref: EMBL:AAL18850.1 xref: EMBL:AAP76376.1 xref: EMBL:BAD92234.1 xref: EMBL:CAH72534.1 xref: EMBL:CAH72535.1 xref: UniProtKB:Q59GW2 xref: UniProtKB:Q5VWR2 xref: UniProtKB:Q96AR1 xref: UniProtKB:Q9NRW4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017635 ! DUSP22_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000412 ! inactivation of MAPK activity relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0058907 name: GLRX2_HUMAN def: "Glutaredoxin-2, mitochondrial precursor" [UniProtKB:Q9NS18] xref: EMBL:AAD34128.1 xref: EMBL:AAF37320.2 xref: EMBL:AAH28113.1 xref: EMBL:AAK72499.1 xref: EMBL:AAK83089.1 xref: EMBL:ABA03170.1 xref: EMBL:CAI10820.1 xref: EMBL:CAI10821.1 xref: UniProtKB:Q3LR69 xref: UniProtKB:Q7L1N7 xref: UniProtKB:Q96JC0 xref: UniProtKB:Q9NS18 xref: UniProtKB:Q9Y3D4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017933 ! GLRX2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: participates_in CCO:P0001269 ! regulation of cell redox homeostasis relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066469 ! GLRX2_HUMAN-cysteine77 [Term] id: CCO:B0058908 name: KCNH7_HUMAN def: "Potassium voltage-gated channel subfamily H member 7" [UniProtKB:Q9NS40] synonym: "Eag-related protein 3" EXACT [UniProtKB:Q9NS40] synonym: "Ether-a-go-go-related gene potassium channel 3" EXACT [UniProtKB:Q9NS40] synonym: "Ether-a-go-go-related protein 3" EXACT [UniProtKB:Q9NS40] synonym: "HERG-3" EXACT [UniProtKB:Q9NS40] synonym: "Voltage-gated potassium channel subunit Kv11.3" EXACT [UniProtKB:Q9NS40] xref: EMBL:AAD01946.1 xref: UniProtKB:Q9NS40 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018396 ! KCNH7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0067293 ! KCNH7_HUMAN-Phosphoserine349 relationship: transforms_into CCO:B0067294 ! KCNH7_HUMAN-Phosphoserine350 relationship: transforms_into CCO:B0067295 ! KCNH7_HUMAN-Phosphoserine353 [Term] id: CCO:B0058909 name: GP173_HUMAN def: "Probable G-protein coupled receptor 173" [UniProtKB:Q9NS66] synonym: "Super conserved receptor expressed in brain 3" EXACT [UniProtKB:Q9NS66] xref: EMBL:AAH09861.1 xref: EMBL:BAA96647.1 xref: UniProtKB:Q9NS66 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017986 ! GPR173_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058910 name: GPR27_HUMAN def: "Probable G-protein coupled receptor 27" [UniProtKB:Q9NS67] synonym: "Super conserved receptor expressed in brain 1" EXACT [UniProtKB:Q9NS67] xref: EMBL:BAA96645.1 xref: UniProtKB:Q9NS67 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018013 ! GPR27_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058911 name: TNR19_HUMAN def: "Tumor necrosis factor receptor superfamily member 19 precursor" [UniProtKB:Q9NS68] synonym: "Toxicity and JNK inducer" EXACT [UniProtKB:Q9NS68] synonym: "TRADE" EXACT [UniProtKB:Q9NS68] xref: EMBL:AAF71828.1 xref: EMBL:AAH47321.1 xref: EMBL:AAK28395.1 xref: EMBL:AAK28396.1 xref: EMBL:AAQ89247.1 xref: EMBL:BAB03269.1 xref: UniProtKB:Q9BXZ9 xref: UniProtKB:Q9BY00 xref: UniProtKB:Q9NS68 xref: UniProtKB:Q9NZV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020315 ! TNFRSF19_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001358 ! tumor necrosis factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019367 ! taj-traf1 physical interaction relationship: participates_in CCO:I0019368 ! taj-traf2 physical interaction relationship: participates_in CCO:I0019369 ! traf5-taj physical interaction relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000772 ! JNK cascade [Term] id: CCO:B0058912 name: FGF21_HUMAN def: "Fibroblast growth factor 21 precursor" [UniProtKB:Q9NSA1] synonym: "FGF-21" EXACT [UniProtKB:Q9NSA1] xref: EMBL:AAQ89444.1 xref: EMBL:BAA99415.1 xref: UniProtKB:Q9NSA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017798 ! FGF21_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058913 name: HOME2_HUMAN def: "Homer protein homolog 2" [UniProtKB:Q9NSB8] synonym: "Cupidin" EXACT [UniProtKB:Q9NSB8] synonym: "Homer-2" EXACT [UniProtKB:Q9NSB8] xref: EMBL:AAC71027.1 xref: EMBL:AAC71028.1 xref: EMBL:AAD13748.1 xref: EMBL:AAH12109.1 xref: EMBL:CAB75537.1 xref: EMBL:CAB75538.1 xref: EMBL:CAB75539.1 xref: EMBL:CAB75540.1 xref: UniProtKB:O95269 xref: UniProtKB:O95349 xref: UniProtKB:Q9NSB6 xref: UniProtKB:Q9NSB7 xref: UniProtKB:Q9NSB8 xref: UniProtKB:Q9UNT7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018153 ! HOMER2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004333 ! GKAP/Homer scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000751 ! metabotropic glutamate receptor signaling pathway [Term] id: CCO:B0058914 name: SALL1_HUMAN def: "Sal-like protein 1" [UniProtKB:Q9NSC2] synonym: "HSal1" EXACT [UniProtKB:Q9NSC2] synonym: "Spalt-like transcription factor 1" EXACT [UniProtKB:Q9NSC2] synonym: "Zinc finger protein SALL1" EXACT [UniProtKB:Q9NSC2] xref: EMBL:AAB99908.1 xref: EMBL:AAF19263.1 xref: EMBL:CAB41399.1 xref: EMBL:CAB41400.1 xref: UniProtKB:Q99881 xref: UniProtKB:Q9NSC2 xref: UniProtKB:Q9NSC3 xref: UniProtKB:Q9P1R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019832 ! SALL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070312 ! SALL1_HUMAN-Phosphoserine586 [Term] id: CCO:B0058915 name: HOME3_HUMAN def: "Homer protein homolog 3" [UniProtKB:Q9NSC5] synonym: "Homer-3" EXACT [UniProtKB:Q9NSC5] xref: EMBL:AAB81545.1 xref: EMBL:AAC71029.1 xref: EMBL:AAH12113.1 xref: EMBL:CAB75536.1 xref: EMBL:CAB75544.1 xref: EMBL:CAB75545.1 xref: UniProtKB:O14580 xref: UniProtKB:O95350 xref: UniProtKB:Q9NSB9 xref: UniProtKB:Q9NSC0 xref: UniProtKB:Q9NSC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018154 ! HOMER3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015427 ! dlc2-homer3 physical interaction relationship: participates_in CCO:I0019439 ! pax6-homer3-1 physical interaction relationship: participates_in CCO:I0019440 ! pax6-homer3-2 physical interaction relationship: participates_in CCO:I0019510 ! pax6-homer3-3 physical interaction relationship: participates_in CCO:P0000751 ! metabotropic glutamate receptor signaling pathway relationship: transforms_into CCO:B0066889 ! HOME3_HUMAN-Phosphoserine159 [Term] id: CCO:B0058916 name: Q9NSC9_HUMAN def: "Olfactory receptor" [UniProtKB:Q9NSC9] xref: EMBL:CAB89291.1 xref: UniProtKB:Q9NSC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021270 ! OR51A1P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058917 name: ZN275_HUMAN def: "Zinc finger protein 275" [UniProtKB:Q9NSD4] xref: UniProtKB:Q9NSD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020689 ! ZNF275_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058918 name: RL3R1_HUMAN def: "Relaxin-3 receptor 1" [UniProtKB:Q9NSD7] synonym: "G protein-coupled receptor SALPR" EXACT [UniProtKB:Q9NSD7] synonym: "GPCR135" EXACT [UniProtKB:Q9NSD7] synonym: "Relaxin family peptide receptor 3" EXACT [UniProtKB:Q9NSD7] synonym: "RLN3 receptor 1" EXACT [UniProtKB:Q9NSD7] synonym: "Somatostatin- and angiotensin-like peptide receptor" EXACT [UniProtKB:Q9NSD7] xref: EMBL:AAI13439.1 xref: EMBL:AAI13441.1 xref: EMBL:AAO92063.1 xref: EMBL:AAQ92315.1 xref: EMBL:BAA93001.1 xref: UniProtKB:Q14DA5 xref: UniProtKB:Q9NSD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019749 ! RXFP3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0003100 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:B0058919 name: CISH_HUMAN def: "Cytokine-inducible SH2-containing protein" [UniProtKB:Q9NSE2] synonym: "CIS" EXACT [UniProtKB:Q9NSE2] synonym: "CIS-1" EXACT [UniProtKB:Q9NSE2] synonym: "Protein G18" EXACT [UniProtKB:Q9NSE2] synonym: "SOCS" EXACT [UniProtKB:Q9NSE2] synonym: "Suppressor of cytokine signaling" EXACT [UniProtKB:Q9NSE2] xref: EMBL:AAD28471.2 xref: EMBL:AAF97410.1 xref: EMBL:AAH31590.1 xref: EMBL:AAH64354.1 xref: EMBL:BAA92328.1 xref: UniProtKB:Q9NS38 xref: UniProtKB:Q9NSE2 xref: UniProtKB:Q9Y5R1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017369 ! CISH_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0018505 ! epor-cish-6 physical interaction relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0058920 name: BRWD1_HUMAN def: "Bromodomain and WD repeat-containing protein 1" [UniProtKB:Q9NSI6] synonym: "WD repeat-containing protein 9" EXACT [UniProtKB:Q9NSI6] xref: EMBL:BAA92123.1 xref: EMBL:BAD74071.1 xref: EMBL:BAD74072.1 xref: EMBL:CAA10896.1 xref: EMBL:CAB90452.1 xref: EMBL:CAC37033.2 xref: EMBL:CAC44371.1 xref: EMBL:CAC44372.1 xref: UniProtKB:O43721 xref: UniProtKB:Q5R2V0 xref: UniProtKB:Q5R2V1 xref: UniProtKB:Q8TCV3 xref: UniProtKB:Q96QG9 xref: UniProtKB:Q96QH0 xref: UniProtKB:Q9NSI6 xref: UniProtKB:Q9NUK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017182 ! BRWD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063992 ! BRWD1_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0063993 ! BRWD1_HUMAN-Phosphoserine701 relationship: transforms_into CCO:B0063994 ! BRWD1_HUMAN-Phosphothreonine1275 relationship: transforms_into CCO:B0063995 ! BRWD1_HUMAN-Phosphoserine1289 relationship: transforms_into CCO:B0063996 ! BRWD1_HUMAN-Phosphoserine1605 relationship: transforms_into CCO:B0063997 ! BRWD1_HUMAN-Phosphoserine1607 relationship: transforms_into CCO:B0063998 ! BRWD1_HUMAN-Phosphoserine1786 relationship: transforms_into CCO:B0063999 ! BRWD1_HUMAN-Phosphoserine1788 relationship: transforms_into CCO:B0064000 ! BRWD1_HUMAN-Phosphoserine1793 relationship: transforms_into CCO:B0064001 ! BRWD1_HUMAN-Phosphoserine1904 relationship: transforms_into CCO:B0064002 ! BRWD1_HUMAN-Phosphoserine1905 relationship: transforms_into CCO:B0064003 ! BRWD1_HUMAN-Phosphoserine1907 relationship: transforms_into CCO:B0064004 ! BRWD1_HUMAN-Phosphoserine1910 relationship: transforms_into CCO:B0064005 ! BRWD1_HUMAN-Phosphoserine2018 relationship: transforms_into CCO:B0064006 ! BRWD1_HUMAN-Phosphoserine2020 relationship: transforms_into CCO:B0064007 ! BRWD1_HUMAN-Phosphoserine2052 [Term] id: CCO:B0058921 name: ZN834_HUMAN def: "Zinc finger protein 834" [UniProtKB:Q9NSJ1] synonym: "Zinc finger protein ZnFP01" EXACT [UniProtKB:Q9NSJ1] xref: EMBL:CAB90395.1 xref: UniProtKB:Q9NSJ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022817 ! ZNF834_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058922 name: Q9NSM3_HUMAN def: "Putative uncharacterized protein DKFZp434B1272" [UniProtKB:Q9NSM3] xref: EMBL:CAB82385.1 xref: UniProtKB:Q9NSM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021271 ! DKFZp434B1272_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0058923 name: TREX1_HUMAN def: "Three prime repair exonuclease 1" [UniProtKB:Q9NSU2] synonym: "3'-5' exonuclease TREX1" EXACT [UniProtKB:Q9NSU2] synonym: "DNase III" EXACT [UniProtKB:Q9NSU2] synonym: "EC 3.1.11.2" EXACT [UniProtKB:Q9NSU2] xref: EMBL:AAD48774.2 xref: EMBL:AAH23630.1 xref: EMBL:AAK07613.1 xref: EMBL:AAK07614.1 xref: EMBL:AAK07615.1 xref: EMBL:AAK07616.1 xref: EMBL:AAL82504.1 xref: EMBL:CAB50866.1 xref: UniProtKB:Q8TEU2 xref: UniProtKB:Q9BPW1 xref: UniProtKB:Q9NSU2 xref: UniProtKB:Q9Y4X2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008464 ! TREX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000645 ! mismatch repair relationship: transforms_into CCO:B0071533 ! TREX1_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0071534 ! TREX1_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0071535 ! TREX1_HUMAN-Phosphoserine316 [Term] id: CCO:B0058924 name: SIRT3_HUMAN def: "NAD-dependent deacetylase sirtuin-3, mitochondrial precursor" [UniProtKB:Q9NTG7] synonym: "EC 3.5.1.-" EXACT [UniProtKB:Q9NTG7] synonym: "hSIRT3" EXACT [UniProtKB:Q9NTG7] synonym: "SIR2-like protein 3" EXACT [UniProtKB:Q9NTG7] xref: EMBL:AAD40851.1 xref: EMBL:AAH01042.1 xref: EMBL:CAB70674.1 xref: UniProtKB:Q9NTG7 xref: UniProtKB:Q9Y6E8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019913 ! SIRT3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0020543 ! dnm1l-sirt3 physical interaction relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058925 name: AT8A2_HUMAN def: "Probable phospholipid-transporting ATPase IB" [UniProtKB:Q9NTI2] synonym: "ATPase class I type 8A member 2" EXACT [UniProtKB:Q9NTI2] synonym: "EC 3.6.3.1" EXACT [UniProtKB:Q9NTI2] synonym: "ML-1" EXACT [UniProtKB:Q9NTI2] xref: EMBL:AAF40215.2 xref: EMBL:BAC04396.1 xref: EMBL:CAB70658.1 xref: EMBL:CAB99084.1 xref: EMBL:CAD97848.1 xref: EMBL:CAH70146.1 xref: EMBL:CAH70513.1 xref: EMBL:CAH70876.1 xref: EMBL:CAH71291.1 xref: EMBL:CAH73647.1 xref: EMBL:CAH74073.1 xref: UniProtKB:Q9H527 xref: UniProtKB:Q9NPU6 xref: UniProtKB:Q9NTI2 xref: UniProtKB:Q9NTL2 xref: UniProtKB:Q9NYM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017091 ! ATP8A2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000490 ! phospholipid-translocating ATPase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0063649 ! AT8A2_HUMAN-Phosphothreonine5 [Term] id: CCO:B0058926 name: ZFP57_HUMAN def: "Zinc finger protein 57 homolog" [UniProtKB:Q9NU63] synonym: "Zfp-57" EXACT [UniProtKB:Q9NU63] synonym: "Zinc finger protein 698" EXACT [UniProtKB:Q9NU63] xref: EMBL:CAB89275.2 xref: EMBL:CAI17624.2 xref: EMBL:CAI18028.2 xref: EMBL:CAI41919.2 xref: EMBL:CAI95569.2 xref: UniProtKB:Q5SSB1 xref: UniProtKB:Q9NU63 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020592 ! ZFP57_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058927 name: PLCX1_HUMAN def: "Phosphatidylinositol-specific phospholipase C X domain-containing protein 1" [UniProtKB:Q9NUJ7] synonym: "PI-PLC X domain-containing protein 1" EXACT [UniProtKB:Q9NUJ7] xref: EMBL:AAH05028.1 xref: EMBL:BAA92127.1 xref: EMBL:CAI43217.1 xref: EMBL:CAM28359.1 xref: EMBL:CAM28360.1 xref: EMBL:EAW66822.1 xref: UniProtKB:A2BH51 xref: UniProtKB:A2BH52 xref: UniProtKB:Q9NUJ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019439 ! PLCXD1_human relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058928 name: TBC23_HUMAN def: "TBC1 domain family member 23" [UniProtKB:Q9NUY8] synonym: "HCV non-structural protein 4A-transactivated protein 1" EXACT [UniProtKB:Q9NUY8] xref: EMBL:AAH10221.1 xref: EMBL:AAH20955.1 xref: EMBL:AAW66944.1 xref: EMBL:BAA91881.1 xref: EMBL:BAA91973.1 xref: EMBL:CAD28488.1 xref: UniProtKB:Q8TCN8 xref: UniProtKB:Q8WUB7 xref: UniProtKB:Q96D90 xref: UniProtKB:Q9NUY8 xref: UniProtKB:Q9NV75 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020165 ! TBC1D23_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071216 ! TBC23_HUMAN-Phosphoserine474 relationship: transforms_into CCO:B0071217 ! TBC23_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0071218 ! TBC23_HUMAN-Phosphothreonine514 [Term] id: CCO:B0058929 name: ZN701_HUMAN def: "Zinc finger protein 701" [UniProtKB:Q9NV72] xref: EMBL:AAH80612.2 xref: EMBL:BAA91884.1 xref: UniProtKB:Q66K42 xref: UniProtKB:Q9NV72 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020907 ! ZNF701_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058930 name: NFIP2_HUMAN def: "NEDD4 family-interacting protein 2" [UniProtKB:Q9NV92] synonym: "NEDD4 WW domain-binding protein 5A" EXACT [UniProtKB:Q9NV92] synonym: "Putative MAPK-activating protein PM04/PM05/PM06/PM07" EXACT [UniProtKB:Q9NV92] synonym: "Putative NF-kappa-B-activating protein 413" EXACT [UniProtKB:Q9NV92] xref: EMBL:AAH21988.1 xref: EMBL:AAH26126.1 xref: EMBL:BAA86479.1 xref: EMBL:BAA91863.1 xref: EMBL:BAC77372.1 xref: EMBL:BAC77381.1 xref: EMBL:BAC77382.1 xref: EMBL:BAC77383.1 xref: EMBL:BAC77384.1 xref: EMBL:CAH71782.1 xref: EMBL:CAH73355.1 xref: UniProtKB:Q7Z2H3 xref: UniProtKB:Q7Z428 xref: UniProtKB:Q8TAR3 xref: UniProtKB:Q9NV92 xref: UniProtKB:Q9ULQ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018777 ! NDFIP2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058931 name: RIC8B_HUMAN def: "Synembryn-B" [UniProtKB:Q9NVN3] synonym: "Brain synembrin" EXACT [UniProtKB:Q9NVN3] synonym: "hSyn" EXACT [UniProtKB:Q9NVN3] synonym: "Protein Ric-8B" EXACT [UniProtKB:Q9NVN3] xref: EMBL:AAH34220.1 xref: EMBL:AAO65923.1 xref: EMBL:BAA91717.1 xref: EMBL:BAC87276.1 xref: UniProtKB:Q4G103 xref: UniProtKB:Q6ZRN4 xref: UniProtKB:Q86WD3 xref: UniProtKB:Q9NVN3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019741 ! RIC8B_human relationship: has_function CCO:F0000253 ! G-protein alpha-subunit binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058932 name: ASF1B_HUMAN def: "Histone chaperone ASF1B" [UniProtKB:Q9NVP2] synonym: "Anti-silencing function protein 1 homolog B" EXACT [UniProtKB:Q9NVP2] synonym: "CCG1-interacting factor A-II" EXACT [UniProtKB:Q9NVP2] synonym: "CIA-II" EXACT [UniProtKB:Q9NVP2] synonym: "hAsf1" EXACT [UniProtKB:Q9NVP2] synonym: "hAsf1b" EXACT [UniProtKB:Q9NVP2] synonym: "hCIA-II" EXACT [UniProtKB:Q9NVP2] xref: EMBL:AAH07726.1 xref: EMBL:AAH10014.1 xref: EMBL:AAH36521.1 xref: EMBL:AAK82973.1 xref: EMBL:BAA91602.1 xref: EMBL:BAA91708.1 xref: EMBL:BAC87709.1 xref: EMBL:BAD96800.1 xref: EMBL:CAG33516.1 xref: UniProtKB:Q53G51 xref: UniProtKB:Q9NVP2 xref: UniProtKB:Q9NVZ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017080 ! ASF1B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063626 ! ASF1B_HUMAN-Phosphoserine142 [Term] id: CCO:B0058933 name: FAIM1_HUMAN def: "Fas apoptotic inhibitory molecule 1" [UniProtKB:Q9NVQ4] xref: EMBL:AAH12478.1 xref: EMBL:BAA91695.1 xref: EMBL:BAC86174.1 xref: UniProtKB:Q9NVQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017758 ! FAIM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0058934 name: RNF12_HUMAN def: "E3 ubiquitin-protein ligase RNF12" [UniProtKB:Q9NVW2] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9NVW2] synonym: "LIM domain-interacting RING finger protein" EXACT [UniProtKB:Q9NVW2] synonym: "R-LIM" EXACT [UniProtKB:Q9NVW2] synonym: "Renal carcinoma antigen NY-REN-43" EXACT [UniProtKB:Q9NVW2] synonym: "RING finger LIM domain-binding protein" EXACT [UniProtKB:Q9NVW2] synonym: "RING finger protein 12" EXACT [UniProtKB:Q9NVW2] xref: EMBL:AAD42875.1 xref: EMBL:BAA91632.1 xref: EMBL:CAC14228.1 xref: UniProtKB:Q9NVW2 xref: UniProtKB:Q9Y598 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019758 ! RNF12_human relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0070105 ! RNF12_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0070106 ! RNF12_HUMAN-Phosphoserine230 [Term] id: CCO:B0058935 name: ZN358_HUMAN def: "Zinc finger protein 358" [UniProtKB:Q9NW07] xref: EMBL:AAH03585.1 xref: EMBL:AAH14002.1 xref: EMBL:BAA91582.1 xref: UniProtKB:Q9BTM7 xref: UniProtKB:Q9NW07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020718 ! ZNF358_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058936 name: IFT57_HUMAN def: "Intraflagellar transport protein 57 homolog" [UniProtKB:Q9NWB7] synonym: "Dermal papilla-derived protein 8" EXACT [UniProtKB:Q9NWB7] synonym: "Estrogen-related receptor beta-like protein 1" EXACT [UniProtKB:Q9NWB7] synonym: "HIP1-interacting protein" EXACT [UniProtKB:Q9NWB7] synonym: "MHS4R2" EXACT [UniProtKB:Q9NWB7] xref: EMBL:AAH09690.2 xref: EMBL:AAH11899.1 xref: EMBL:AAK13588.1 xref: EMBL:AAK28373.1 xref: EMBL:BAA91466.1 xref: EMBL:BAB87803.1 xref: EMBL:CAG33532.1 xref: EMBL:EAW79730.1 xref: UniProtKB:Q96DA9 xref: UniProtKB:Q9NWB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018235 ! IFT57_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000484 ! basal body relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0058937 name: Q9NWF0_HUMAN xref: UniProtKB:Q9NWF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058938 name: SLTM_HUMAN def: "SAFB-like transcription modulator" [UniProtKB:Q9NWH9] synonym: "Modulator of estrogen-induced transcription" EXACT [UniProtKB:Q9NWH9] xref: EMBL:AAH14944.1 xref: EMBL:AAH46119.3 xref: EMBL:AAI08657.1 xref: EMBL:BAA91401.1 xref: EMBL:BAB14502.1 xref: EMBL:BAB14971.1 xref: EMBL:BAD18423.1 xref: EMBL:CAH56362.1 xref: UniProtKB:Q2VPK7 xref: UniProtKB:Q52MB3 xref: UniProtKB:Q658J7 xref: UniProtKB:Q6ZNF2 xref: UniProtKB:Q86TK6 xref: UniProtKB:Q9H7C3 xref: UniProtKB:Q9H8U9 xref: UniProtKB:Q9NWH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019936 ! SLTM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070579 ! SLTM_HUMAN-Phosphoserine93 relationship: transforms_into CCO:B0070580 ! SLTM_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0070581 ! SLTM_HUMAN-Phosphoserine139 relationship: transforms_into CCO:B0070582 ! SLTM_HUMAN-Phosphoserine289 relationship: transforms_into CCO:B0070583 ! SLTM_HUMAN-Phosphoserine421 relationship: transforms_into CCO:B0070584 ! SLTM_HUMAN-Phosphoserine550 relationship: transforms_into CCO:B0070585 ! SLTM_HUMAN-Phosphoserine551 relationship: transforms_into CCO:B0070586 ! SLTM_HUMAN-Phosphoserine553 relationship: transforms_into CCO:B0070587 ! SLTM_HUMAN-Phosphoserine590 relationship: transforms_into CCO:B0070588 ! SLTM_HUMAN-Phosphoserine1002 relationship: transforms_into CCO:B0070589 ! SLTM_HUMAN-Phosphoserine1014 [Term] id: CCO:B0058939 name: PAG1_HUMAN def: "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1" [UniProtKB:Q9NWQ8] synonym: "Csk-binding protein" EXACT [UniProtKB:Q9NWQ8] synonym: "Transmembrane adapter protein PAG" EXACT [UniProtKB:Q9NWQ8] synonym: "Transmembrane phosphoprotein Cbp" EXACT [UniProtKB:Q9NWQ8] xref: EMBL:AAF67343.1 xref: EMBL:AAH90931.1 xref: EMBL:AAI12160.1 xref: EMBL:BAA91321.1 xref: UniProtKB:Q2M1Z9 xref: UniProtKB:Q5BKU4 xref: UniProtKB:Q9NWQ8 xref: UniProtKB:Q9NYK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019289 ! PAG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002981 ! regulation of T cell activation relationship: participates_in CCO:P0002986 ! negative regulation of T cell activation relationship: transforms_into CCO:B0069054 ! PAG1_HUMAN-Phosphotyrosine163 relationship: transforms_into CCO:B0069055 ! PAG1_HUMAN-Phosphotyrosine181 relationship: transforms_into CCO:B0069056 ! PAG1_HUMAN-Phosphotyrosine227 relationship: transforms_into CCO:B0069057 ! PAG1_HUMAN-Phosphotyrosine317 relationship: transforms_into CCO:B0069058 ! PAG1_HUMAN-Phosphotyrosine341 relationship: transforms_into CCO:B0069059 ! PAG1_HUMAN-Phosphotyrosine359 relationship: transforms_into CCO:B0069060 ! PAG1_HUMAN-Phosphotyrosine387 relationship: transforms_into CCO:B0069061 ! PAG1_HUMAN-Phosphotyrosine417 [Term] id: CCO:B0058940 name: PK1IP_HUMAN def: "p21-activated protein kinase-interacting protein 1" [UniProtKB:Q9NWT1] synonym: "hPIP1" EXACT [UniProtKB:Q9NWT1] synonym: "PAK/PLC-interacting protein 1" EXACT [UniProtKB:Q9NWT1] synonym: "PAK1-interacting protein 1" EXACT [UniProtKB:Q9NWT1] synonym: "WD repeat-containing protein 84" EXACT [UniProtKB:Q9NWT1] xref: EMBL:AAH10907.1 xref: EMBL:AAK57477.1 xref: EMBL:BAA91296.1 xref: EMBL:CAI14002.1 xref: UniProtKB:Q5T4J2 xref: UniProtKB:Q96QJ8 xref: UniProtKB:Q96T87 xref: UniProtKB:Q9NWT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019405 ! PAK1IP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0069318 ! PK1IP_HUMAN-Phosphoserine320 [Term] id: CCO:B0058941 name: HIF1N_HUMAN def: "Hypoxia-inducible factor 1-alpha inhibitor" [UniProtKB:Q9NWT6] synonym: "EC 1.14.11.16" EXACT [UniProtKB:Q9NWT6] synonym: "Factor inhibiting HIF-1" EXACT [UniProtKB:Q9NWT6] synonym: "FIH-1" EXACT [UniProtKB:Q9NWT6] synonym: "Hypoxia-inducible factor asparagine hydroxylase" EXACT [UniProtKB:Q9NWT6] xref: EMBL:AAH07719.1 xref: EMBL:AAL27308.1 xref: EMBL:BAA91291.1 xref: EMBL:CAB94885.1 xref: EMBL:CAH73566.1 xref: UniProtKB:Q5W147 xref: UniProtKB:Q969Q7 xref: UniProtKB:Q9NPV5 xref: UniProtKB:Q9NWT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018131 ! HIF1AN_human relationship: has_function CCO:F0000979 ! peptide-aspartate beta-dioxygenase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015193 ! asb9-hif1an physical interaction relationship: participates_in CCO:I0015339 ! asb13-hif1an physical interaction relationship: participates_in CCO:I0015728 ! hif1an-invs physical interaction relationship: participates_in CCO:I0018400 ! hif1a-hif1an-1 direct interaction relationship: participates_in CCO:I0018401 ! hif1a-hif1an-2 direct interaction relationship: participates_in CCO:I0018402 ! hif1a-hif1an-3 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058942 name: CLN6_HUMAN def: "Ceroid-lipofuscinosis neuronal protein 6" [UniProtKB:Q9NWW5] synonym: "Protein CLN6" EXACT [UniProtKB:Q9NWW5] xref: EMBL:AAH10849.1 xref: EMBL:AAH13130.1 xref: EMBL:BAA91260.1 xref: EMBL:BAB55226.1 xref: EMBL:CAG33525.1 xref: UniProtKB:Q6IAB1 xref: UniProtKB:Q96SR0 xref: UniProtKB:Q9NWW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017389 ! CLN6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002579 ! positive regulation of proteolysis relationship: transforms_into CCO:B0064391 ! CLN6_HUMAN-Phosphoserine31 [Term] id: CCO:B0058943 name: ASB6_HUMAN def: "Ankyrin repeat and SOCS box protein 6" [UniProtKB:Q9NWX5] synonym: "ASB-6" EXACT [UniProtKB:Q9NWX5] xref: EMBL:AAH65913.1 xref: EMBL:BAA91250.1 xref: EMBL:BAB14355.1 xref: UniProtKB:Q9NWX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017070 ! ASB6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058944 name: IRAK4_HUMAN def: "Interleukin-1 receptor-associated kinase 4" [UniProtKB:Q9NWZ3] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9NWZ3] synonym: "IRAK-4" EXACT [UniProtKB:Q9NWZ3] synonym: "NY-REN-64 antigen" EXACT [UniProtKB:Q9NWZ3] xref: EMBL:AAD42884.1 xref: EMBL:AAH13316.1 xref: EMBL:AAM15772.1 xref: EMBL:AAN75440.1 xref: EMBL:BAA91232.1 xref: UniProtKB:Q8TDF7 xref: UniProtKB:Q9NWZ3 xref: UniProtKB:Q9Y589 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018311 ! IRAK4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015994 ! st2-irak4-1 physical interaction relationship: participates_in CCO:I0017857 ! peli1-irak1-1 physical interaction relationship: participates_in CCO:I0018034 ! pellino-irak-irak4 physical interaction relationship: participates_in CCO:I0018146 ! irak4-peli2-4 phosphorylation relationship: participates_in CCO:I0018774 ! irak4-peli2-3 physical interaction relationship: participates_in CCO:I0019233 ! irak4-peli2-1 physical interaction relationship: participates_in CCO:I0020577 ! irak4-tbpl1 physical interaction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0058945 name: NALP2_HUMAN def: "NACHT, LRR and PYD domains-containing protein 2" [UniProtKB:Q9NX02] synonym: "Nucleotide-binding site protein 1" EXACT [UniProtKB:Q9NX02] synonym: "PYRIN domain and NACHT domain-containing protein 1" EXACT [UniProtKB:Q9NX02] synonym: "PYRIN-containing APAF1-like protein 2" EXACT [UniProtKB:Q9NX02] xref: EMBL:AAG15253.1 xref: EMBL:AAG30289.1 xref: EMBL:AAH01039.1 xref: EMBL:AAH03592.1 xref: EMBL:AAH39269.1 xref: EMBL:AAL69962.1 xref: EMBL:BAA91223.1 xref: EMBL:BAA91377.1 xref: EMBL:BAB15293.1 xref: EMBL:BAD92537.1 xref: EMBL:BAD96973.1 xref: EMBL:BAD96989.1 xref: UniProtKB:Q53FL5 xref: UniProtKB:Q59G09 xref: UniProtKB:Q8IXT0 xref: UniProtKB:Q9BVN5 xref: UniProtKB:Q9H6G6 xref: UniProtKB:Q9HAV9 xref: UniProtKB:Q9NWK3 xref: UniProtKB:Q9NX02 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018711 ! NLRP2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004944 ! Pyrin domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002178 ! positive regulation of caspase activity [Term] id: CCO:B0058946 name: DDT4_HUMAN def: "DNA-damage-inducible transcript 4 protein" [UniProtKB:Q9NX09] synonym: "HIF-1 responsive protein RTP801" EXACT [UniProtKB:Q9NX09] synonym: "Protein regulated in development and DNA damage response 1" EXACT [UniProtKB:Q9NX09] synonym: "REDD-1" EXACT [UniProtKB:Q9NX09] xref: EMBL:AAH00708.1 xref: EMBL:AAH07714.1 xref: EMBL:AAH15236.1 xref: EMBL:AAL38424.1 xref: EMBL:AAM10442.1 xref: EMBL:BAA91214.1 xref: EMBL:CAB66603.1 xref: EMBL:CAH73863.1 xref: EMBL:EAW54452.1 xref: UniProtKB:Q9H0S3 xref: UniProtKB:Q9NX09 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017544 ! DDIT4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:B0058947 name: SOLH2_HUMAN def: "Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2" [UniProtKB:Q9NX45] xref: EMBL:AAH25383.1 xref: EMBL:AAW78547.1 xref: EMBL:BAA91175.1 xref: EMBL:CAC42466.1 xref: EMBL:EAX08554.1 xref: EMBL:EAX08555.1 xref: UniProtKB:Q5EGC3 xref: UniProtKB:Q8TC74 xref: UniProtKB:Q96QX4 xref: UniProtKB:Q9NX45 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019979 ! SOHLH2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058948 name: RHBL2_HUMAN def: "Rhomboid-related protein 2" [UniProtKB:Q9NX52] synonym: "EC 3.4.21.105" EXACT [UniProtKB:Q9NX52] synonym: "Rhomboid-like protein 2" EXACT [UniProtKB:Q9NX52] synonym: "RRP2" EXACT [UniProtKB:Q9NX52] xref: EMBL:AAH13103.1 xref: EMBL:AAM95697.1 xref: EMBL:BAA91168.1 xref: EMBL:CAI23052.1 xref: UniProtKB:Q6P175 xref: UniProtKB:Q8NER8 xref: UniProtKB:Q96E02 xref: UniProtKB:Q9NX52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019708 ! RHBDL2_human relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058949 name: RAB20_HUMAN def: "Ras-related protein Rab-20" [UniProtKB:Q9NX57] xref: EMBL:AAH26025.1 xref: EMBL:BAA91163.1 xref: EMBL:BAA91171.1 xref: EMBL:CAC81247.1 xref: UniProtKB:Q9NX49 xref: UniProtKB:Q9NX57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019578 ! RAB20_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058950 name: ZN434_HUMAN def: "Zinc finger protein 434" [UniProtKB:Q9NX65] synonym: "Cervical cancer suppressor gene 5 protein" EXACT [UniProtKB:Q9NX65] synonym: "HCCS-5" EXACT [UniProtKB:Q9NX65] xref: EMBL:AAM73658.1 xref: EMBL:AAP57398.1 xref: EMBL:BAA91155.1 xref: UniProtKB:Q7Z6G2 xref: UniProtKB:Q8NFX8 xref: UniProtKB:Q9NX65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020748 ! ZNF434_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058951 name: SIRT5_HUMAN def: "NAD-dependent deacetylase sirtuin-5" [UniProtKB:Q9NXA8] synonym: "EC 3.5.1.-" EXACT [UniProtKB:Q9NXA8] synonym: "SIR2-like protein 5" EXACT [UniProtKB:Q9NXA8] xref: EMBL:AAD40853.1 xref: EMBL:AAH00126.1 xref: EMBL:BAA91107.1 xref: EMBL:CAI19838.1 xref: EMBL:CAL38292.1 xref: UniProtKB:Q5T294 xref: UniProtKB:Q9NXA8 xref: UniProtKB:Q9Y6E6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019915 ! SIRT5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058952 name: CNTLN_HUMAN def: "Centlein" [UniProtKB:Q9NXG0] synonym: "Centrosomal protein" EXACT [UniProtKB:Q9NXG0] xref: EMBL:BAA91052.1 xref: EMBL:BAB13850.1 xref: EMBL:BAC05319.1 xref: EMBL:CAH70424.1 xref: EMBL:CAH70425.1 xref: EMBL:CAH70743.2 xref: EMBL:CAH72682.2 xref: EMBL:CAH72684.1 xref: EMBL:CAI14630.2 xref: EMBL:CAI16195.2 xref: UniProtKB:A5Z2X6 xref: UniProtKB:Q5VYJ0 xref: UniProtKB:Q8N1G9 xref: UniProtKB:Q9HAJ5 xref: UniProtKB:Q9NXG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017413 ! CNTLN_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058953 name: PP14D_HUMAN def: "Protein phosphatase 1 regulatory subunit 14D" [UniProtKB:Q9NXH3] synonym: "Gastrointestinal and brain-specific PP1-inhibitory protein 1" EXACT [UniProtKB:Q9NXH3] synonym: "GBPI-1" EXACT [UniProtKB:Q9NXH3] xref: EMBL:AAH96716.1 xref: EMBL:AAH98124.1 xref: EMBL:AAL25829.1 xref: EMBL:BAA91037.1 xref: UniProtKB:Q4V773 xref: UniProtKB:Q9NXH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019474 ! PPP1R14D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002057 ! regulation of phosphorylation relationship: transforms_into CCO:B0069447 ! PP14D_HUMAN-Phosphothreonine58 [Term] id: CCO:B0058954 name: M4A12_HUMAN def: "Membrane-spanning 4-domains subfamily A member 12" [UniProtKB:Q9NXJ0] xref: EMBL:AAH29793.1 xref: EMBL:BAA91020.1 xref: UniProtKB:Q8N6L4 xref: UniProtKB:Q9NXJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018541 ! MS4A12_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058955 name: YD003_HUMAN def: "Putative Rho guanine nucleotide exchange factor FLJ20184" [UniProtKB:Q9NXL2] xref: EMBL:AAI05696.1 xref: EMBL:BAA90998.1 xref: EMBL:EAX06187.1 xref: UniProtKB:Q9NXL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0058956 name: ZN586_HUMAN def: "Zinc finger protein 586" [UniProtKB:Q9NXT0] xref: EMBL:BAA90930.1 xref: EMBL:BAG63522.1 xref: EMBL:EAW72533.1 xref: UniProtKB:A8MY63 xref: UniProtKB:Q9NXT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020839 ! ZNF586_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058957 name: CLC5A_HUMAN def: "C-type lectin domain family 5 member A" [UniProtKB:Q9NY25] synonym: "C-type lectin superfamily member 5" EXACT [UniProtKB:Q9NY25] synonym: "MDL-1" EXACT [UniProtKB:Q9NY25] synonym: "Myeloid DAP12-associating lectin" EXACT [UniProtKB:Q9NY25] xref: EMBL:AAF02491.1 xref: EMBL:AAH93714.1 xref: EMBL:AAI12100.1 xref: EMBL:AAI13099.1 xref: EMBL:AAS07444.1 xref: EMBL:CAB71334.1 xref: UniProtKB:Q52M11 xref: UniProtKB:Q9NY25 xref: UniProtKB:Q9UKQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017380 ! CLEC5A_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058958 name: BARH2_HUMAN def: "BarH-like 2 homeobox protein" [UniProtKB:Q9NY43] xref: EMBL:AAI26440.1 xref: EMBL:AAI26442.1 xref: EMBL:AAQ01189.1 xref: EMBL:CAB92440.1 xref: UniProtKB:A0AVP2 xref: UniProtKB:Q7Z4N7 xref: UniProtKB:Q9NY43 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017126 ! BARHL2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001276 ! regulation of axon extension relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002524 ! positive regulation of translation [Term] id: CCO:B0058959 name: Q9NY94_HUMAN def: "SCL protein" [UniProtKB:Q9NY94] xref: EMBL:CAB72254.1 xref: UniProtKB:Q9NY94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021272 ! SCL_human relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0058960 name: DACT1_HUMAN def: "Dapper homolog 1" [UniProtKB:Q9NYF0] synonym: "hDPR1" EXACT [UniProtKB:Q9NYF0] synonym: "Hepatocellular carcinoma novel gene 3 protein" EXACT [UniProtKB:Q9NYF0] xref: EMBL:AAF65569.1 xref: EMBL:CAD61905.1 xref: EMBL:DAA00310.1 xref: UniProtKB:Q86TY0 xref: UniProtKB:Q9NYF0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017519 ! DACT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0058961 name: FA13B_HUMAN def: "Protein FAM13B1" [UniProtKB:Q9NYF5] synonym: "GAP-like protein N61" EXACT [UniProtKB:Q9NYF5] xref: EMBL:AAF63764.1 xref: EMBL:AAF67482.1 xref: EMBL:AAH56887.1 xref: UniProtKB:Q6PGQ2 xref: UniProtKB:Q9NYF5 xref: UniProtKB:Q9P0I7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021117 ! FAM13B1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058962 name: BCLF1_HUMAN def: "Bcl-2-associated transcription factor 1" [UniProtKB:Q9NYF8] synonym: "Btf" EXACT [UniProtKB:Q9NYF8] xref: EMBL:AAF64304.1 xref: EMBL:AAH47687.1 xref: EMBL:AAH47887.1 xref: EMBL:AAH56894.1 xref: EMBL:AAH63846.1 xref: EMBL:BAA11481.2 xref: EMBL:CAB96722.1 xref: UniProtKB:Q14673 xref: UniProtKB:Q86WU6 xref: UniProtKB:Q86WY0 xref: UniProtKB:Q9NYF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017140 ! BCLAF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017678 ! emd-bclaf1-3 physical interaction relationship: participates_in CCO:I0018300 ! emd-bclaf1-1 physical interaction relationship: participates_in CCO:I0018301 ! emd-bclaf1-2 direct interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0063813 ! BCLF1_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0063814 ! BCLF1_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0063815 ! BCLF1_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0063816 ! BCLF1_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0063817 ! BCLF1_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0063818 ! BCLF1_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0063819 ! BCLF1_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0063820 ! BCLF1_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0063821 ! BCLF1_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0063822 ! BCLF1_HUMAN-Phosphoserine183 relationship: transforms_into CCO:B0063823 ! BCLF1_HUMAN-Phosphoserine198 relationship: transforms_into CCO:B0063824 ! BCLF1_HUMAN-Phosphoserine217 relationship: transforms_into CCO:B0063825 ! BCLF1_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0063826 ! BCLF1_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0063827 ! BCLF1_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0063828 ! BCLF1_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0063829 ! BCLF1_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0063830 ! BCLF1_HUMAN-Phosphotyrosine284 relationship: transforms_into CCO:B0063831 ! BCLF1_HUMAN-Phosphoserine285 relationship: transforms_into CCO:B0063832 ! BCLF1_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0063833 ! BCLF1_HUMAN-Phosphoserine290 relationship: transforms_into CCO:B0063834 ! BCLF1_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0063835 ! BCLF1_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0063836 ! BCLF1_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0063837 ! BCLF1_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0063838 ! BCLF1_HUMAN-Phosphothreonine341 relationship: transforms_into CCO:B0063839 ! BCLF1_HUMAN-Phosphoserine385 relationship: transforms_into CCO:B0063840 ! BCLF1_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0063841 ! BCLF1_HUMAN-Phosphoserine397 relationship: transforms_into CCO:B0063842 ! BCLF1_HUMAN-Phosphothreonine402 relationship: transforms_into CCO:B0063843 ! BCLF1_HUMAN-Phosphothreonine405 relationship: transforms_into CCO:B0063844 ! BCLF1_HUMAN-Phosphotyrosine408 relationship: transforms_into CCO:B0063845 ! BCLF1_HUMAN-Phosphoserine443 relationship: transforms_into CCO:B0063846 ! BCLF1_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0063847 ! BCLF1_HUMAN-Phosphothreonine489 relationship: transforms_into CCO:B0063848 ! BCLF1_HUMAN-Phosphothreonine494 relationship: transforms_into CCO:B0063849 ! BCLF1_HUMAN-Phosphoserine496 relationship: transforms_into CCO:B0063850 ! BCLF1_HUMAN-Phosphoserine502 relationship: transforms_into CCO:B0063851 ! BCLF1_HUMAN-Phosphotyrosine511 relationship: transforms_into CCO:B0063852 ! BCLF1_HUMAN-Phosphoserine512 relationship: transforms_into CCO:B0063853 ! BCLF1_HUMAN-Phosphoserine525 relationship: transforms_into CCO:B0063854 ! BCLF1_HUMAN-Phosphothreonine526 relationship: transforms_into CCO:B0063855 ! BCLF1_HUMAN-Phosphoserine531 relationship: transforms_into CCO:B0063856 ! BCLF1_HUMAN-Phosphoserine578 relationship: transforms_into CCO:B0063857 ! BCLF1_HUMAN-Phosphoserine648 relationship: transforms_into CCO:B0063858 ! BCLF1_HUMAN-Phosphoserine658 relationship: transforms_into CCO:B0063859 ! BCLF1_HUMAN-Phosphothreonine661 relationship: transforms_into CCO:B0063860 ! BCLF1_HUMAN-Phosphoserine690 relationship: transforms_into CCO:B0063861 ! BCLF1_HUMAN-Phosphoserine711 relationship: transforms_into CCO:B0063862 ! BCLF1_HUMAN-Phosphoserine720 relationship: transforms_into CCO:B0063863 ! BCLF1_HUMAN-Phosphoserine760 relationship: transforms_into CCO:B0063864 ! BCLF1_HUMAN-Phosphothreonine840 [Term] id: CCO:B0058963 name: PSD3_HUMAN def: "PH and SEC7 domain-containing protein 3" [UniProtKB:Q9NYI0] synonym: "Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6" EXACT [UniProtKB:Q9NYI0] synonym: "Hepatocellular carcinoma-associated antigen 67" EXACT [UniProtKB:Q9NYI0] synonym: "Pleckstrin homology and SEC7 domain-containing protein 3" EXACT [UniProtKB:Q9NYI0] xref: EMBL:AAF61269.2 xref: EMBL:AAH75044.1 xref: EMBL:AAH75045.1 xref: EMBL:AAM74203.1 xref: EMBL:BAA76786.2 xref: UniProtKB:A6NFQ4 xref: UniProtKB:Q6B003 xref: UniProtKB:Q9NYI0 xref: UniProtKB:Q9Y2F1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019526 ! PSD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0069565 ! PSD3_HUMAN-Phosphoserine770 relationship: transforms_into CCO:B0069566 ! PSD3_HUMAN-Phosphoserine1011 relationship: transforms_into CCO:B0069567 ! PSD3_HUMAN-Phosphoserine1012 relationship: transforms_into CCO:B0069568 ! PSD3_HUMAN-Phosphoserine1020 [Term] id: CCO:B0058964 name: TLR7_HUMAN def: "Toll-like receptor 7 precursor" [UniProtKB:Q9NYK1] xref: EMBL:AAF60188.1 xref: EMBL:AAF78035.1 xref: EMBL:AAH33651.1 xref: EMBL:AAQ88659.1 xref: UniProtKB:Q9NR98 xref: UniProtKB:Q9NYK1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020282 ! TLR7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002270 ! positive regulation of interferon-gamma biosynthetic process relationship: participates_in CCO:P0002297 ! positive regulation of interferon-alpha biosynthetic process relationship: participates_in CCO:P0002300 ! positive regulation of interferon-beta biosynthetic process relationship: participates_in CCO:P0002357 ! positive regulation of interleukin-8 biosynthetic process relationship: transforms_into CCO:B0071420 ! TLR7_HUMAN-Phosphoserine1010 [Term] id: CCO:B0058965 name: GPR83_HUMAN def: "Probable G-protein coupled receptor 83 precursor" [UniProtKB:Q9NYM4] synonym: "G-protein coupled receptor 72" EXACT [UniProtKB:Q9NYM4] xref: EMBL:AAF43705.1 xref: EMBL:AAH67473.1 xref: EMBL:BAA96064.1 xref: EMBL:BAG37605.1 xref: EMBL:EAW66929.1 xref: UniProtKB:Q6NWR4 xref: UniProtKB:Q9NYM4 xref: UniProtKB:Q9P1Y8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018035 ! GPR83_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001321 ! neuropeptide Y receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058966 name: RASLC_HUMAN def: "Ras-like protein family member 12" [UniProtKB:Q9NYN1] synonym: "RAS-like protein Ris" EXACT [UniProtKB:Q9NYN1] xref: EMBL:AAF60286.1 xref: EMBL:AAH53734.1 xref: EMBL:EAW77709.1 xref: UniProtKB:Q9NYN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019631 ! RASL12_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058967 name: Q9NYN8_HUMAN xref: UniProtKB:Q9NYN8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058968 name: CELR1_HUMAN def: "Cadherin EGF LAG seven-pass G-type receptor 1 precursor" [UniProtKB:Q9NYQ6] synonym: "Flamingo homolog 2" EXACT [UniProtKB:Q9NYQ6] synonym: "hFmi2" EXACT [UniProtKB:Q9NYQ6] xref: EMBL:AAF61930.1 xref: EMBL:AAH00059.2 xref: EMBL:CAI19319.1 xref: EMBL:CAI20967.1 xref: EMBL:CAI23555.1 xref: UniProtKB:O95722 xref: UniProtKB:Q5TH47 xref: UniProtKB:Q9BWQ5 xref: UniProtKB:Q9NYQ6 xref: UniProtKB:Q9Y506 xref: UniProtKB:Q9Y526 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017328 ! CELSR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020273 ! celsr1-psap physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway relationship: transforms_into CCO:B0064253 ! CELR1_HUMAN-3-hydroxyasparagine1666 relationship: transforms_into CCO:B0064254 ! CELR1_HUMAN-3-hydroxyaspartate1889 relationship: transforms_into CCO:B0064255 ! CELR1_HUMAN-Phosphoserine2761 relationship: transforms_into CCO:B0064256 ! CELR1_HUMAN-Phosphoserine2764 [Term] id: CCO:B0058969 name: KBRS2_HUMAN def: "NF-kappa-B inhibitor-interacting Ras-like protein 2" [UniProtKB:Q9NYR9] synonym: "I-kappa-B-interacting Ras-like protein 2" EXACT [UniProtKB:Q9NYR9] synonym: "Kappa B-Ras protein 2" EXACT [UniProtKB:Q9NYR9] synonym: "KappaB-Ras2" EXACT [UniProtKB:Q9NYR9] xref: EMBL:AAF34999.1 xref: EMBL:AAH07450.1 xref: EMBL:AAH63498.1 xref: EMBL:ABC40741.1 xref: EMBL:BAB55006.1 xref: EMBL:CAB70873.2 xref: EMBL:EAW60791.1 xref: UniProtKB:A6NCZ5 xref: UniProtKB:Q6PK52 xref: UniProtKB:Q96KC7 xref: UniProtKB:Q9NSX1 xref: UniProtKB:Q9NYR9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018377 ! NKIRAS2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058970 name: KBRS1_HUMAN def: "NF-kappa-B inhibitor-interacting Ras-like protein 1" [UniProtKB:Q9NYS0] synonym: "I-kappa-B-interacting Ras-like protein 1" EXACT [UniProtKB:Q9NYS0] synonym: "Kappa B-Ras protein 1" EXACT [UniProtKB:Q9NYS0] synonym: "KappaB-Ras1" EXACT [UniProtKB:Q9NYS0] xref: EMBL:AAF34998.1 xref: EMBL:AAH12145.1 xref: EMBL:AAH66940.1 xref: EMBL:ABC40740.1 xref: EMBL:BAB55341.1 xref: UniProtKB:Q96K18 xref: UniProtKB:Q9NYS0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018376 ! NKIRAS1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0058971 name: WSB2_HUMAN def: "WD repeat and SOCS box-containing protein 2" [UniProtKB:Q9NYS7] synonym: "CS box-containing WD protein" EXACT [UniProtKB:Q9NYS7] synonym: "WSB-2" EXACT [UniProtKB:Q9NYS7] xref: EMBL:AAF71302.1 xref: EMBL:AAF80478.1 xref: EMBL:AAH15887.1 xref: UniProtKB:Q9NRX9 xref: UniProtKB:Q9NYS7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020501 ! WSB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020306 ! ezh2-wsb2 physical interaction relationship: participates_in CCO:I0020657 ! rpn1-wsb2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0058972 name: PLEK2_HUMAN def: "Pleckstrin-2" [UniProtKB:Q9NYT0] xref: EMBL:AAF34791.1 xref: EMBL:AAH01226.1 xref: EMBL:AAH08056.2 xref: UniProtKB:Q96JT0 xref: UniProtKB:Q9NYT0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019442 ! PLEK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069412 ! PLEK2_HUMAN-Phosphotyrosine333 [Term] id: CCO:B0058973 name: ZN226_HUMAN def: "Zinc finger protein 226" [UniProtKB:Q9NYT6] xref: EMBL:AAF34786.1 xref: EMBL:AAF88103.1 xref: EMBL:AAH24197.1 xref: EMBL:BAB14398.1 xref: UniProtKB:Q96TE6 xref: UniProtKB:Q9NS44 xref: UniProtKB:Q9NYT6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020666 ! ZNF226_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058974 name: RRN3_HUMAN def: "RNA polymerase I-specific transcription initiation factor RRN3" [UniProtKB:Q9NYV6] synonym: "TIF-IA" EXACT [UniProtKB:Q9NYV6] synonym: "Transcription initiation factor IA" EXACT [UniProtKB:Q9NYV6] xref: EMBL:AAF66160.1 xref: EMBL:AAH71868.1 xref: EMBL:CAC07955.1 xref: UniProtKB:Q6IPL4 xref: UniProtKB:Q9H4F0 xref: UniProtKB:Q9NYV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019796 ! RRN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070193 ! RRN3_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0070194 ! RRN3_HUMAN-Phosphoserine170 relationship: transforms_into CCO:B0070195 ! RRN3_HUMAN-Phosphoserine172 relationship: transforms_into CCO:B0070196 ! RRN3_HUMAN-Phosphoserine640 [Term] id: CCO:B0058975 name: T2R16_HUMAN def: "Taste receptor type 2 member 16" [UniProtKB:Q9NYV7] synonym: "T2R16" EXACT [UniProtKB:Q9NYV7] xref: EMBL:AAF43912.1 xref: EMBL:AAH95524.1 xref: EMBL:AAP21892.1 xref: EMBL:AAU21158.1 xref: UniProtKB:Q502V3 xref: UniProtKB:Q549U8 xref: UniProtKB:Q645W1 xref: UniProtKB:Q9NYV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020097 ! TAS2R16_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005055 ! bitter taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058976 name: T2R14_HUMAN def: "Taste receptor type 2 member 14" [UniProtKB:Q9NYV8] synonym: "T2R14" EXACT [UniProtKB:Q9NYV8] synonym: "Taste receptor family B member 1" EXACT [UniProtKB:Q9NYV8] synonym: "TRB1" EXACT [UniProtKB:Q9NYV8] xref: EMBL:AAF43911.1 xref: EMBL:AAH69148.1 xref: EMBL:AAI01994.1 xref: EMBL:AAI01995.1 xref: EMBL:AAI03700.1 xref: EMBL:AAU21146.1 xref: UniProtKB:Q645X3 xref: UniProtKB:Q9NYV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020096 ! TAS2R14_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_function CCO:F0005055 ! bitter taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058977 name: T2R13_HUMAN def: "Taste receptor type 2 member 13" [UniProtKB:Q9NYV9] synonym: "T2R13" EXACT [UniProtKB:Q9NYV9] synonym: "Taste receptor family B member 3" EXACT [UniProtKB:Q9NYV9] synonym: "TRB3" EXACT [UniProtKB:Q9NYV9] xref: EMBL:AAF43910.1 xref: EMBL:AAH69376.1 xref: EMBL:AAH95518.1 xref: EMBL:AAU21147.1 xref: UniProtKB:Q4G0I5 xref: UniProtKB:Q502V8 xref: UniProtKB:Q645X2 xref: UniProtKB:Q9NYV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020095 ! TAS2R13_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058978 name: T2R10_HUMAN def: "Taste receptor type 2 member 10" [UniProtKB:Q9NYW0] synonym: "T2R10" EXACT [UniProtKB:Q9NYW0] synonym: "Taste receptor family B member 2" EXACT [UniProtKB:Q9NYW0] synonym: "TRB2" EXACT [UniProtKB:Q9NYW0] xref: EMBL:AAF43909.1 xref: EMBL:AAH69089.1 xref: EMBL:AAI01763.1 xref: EMBL:AAI01765.1 xref: EMBL:AAU21148.1 xref: UniProtKB:Q3MIM9 xref: UniProtKB:Q6NTD9 xref: UniProtKB:Q9NYW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020093 ! TAS2R10_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058979 name: TA2R9_HUMAN def: "Taste receptor type 2 member 9" [UniProtKB:Q9NYW1] synonym: "T2R9" EXACT [UniProtKB:Q9NYW1] synonym: "Taste receptor family B member 6" EXACT [UniProtKB:Q9NYW1] synonym: "TRB6" EXACT [UniProtKB:Q9NYW1] xref: EMBL:AAF43908.1 xref: EMBL:AAH69066.1 xref: EMBL:AAH95519.1 xref: EMBL:AAU21150.1 xref: EMBL:BAD97966.1 xref: EMBL:BAD97967.1 xref: EMBL:BAD97968.1 xref: UniProtKB:Q502V7 xref: UniProtKB:Q50KT0 xref: UniProtKB:Q50KT1 xref: UniProtKB:Q645W9 xref: UniProtKB:Q9NYW1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020118 ! TAS2R9_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058980 name: TA2R8_HUMAN def: "Taste receptor type 2 member 8" [UniProtKB:Q9NYW2] synonym: "T2R8" EXACT [UniProtKB:Q9NYW2] synonym: "Taste receptor family B member 5" EXACT [UniProtKB:Q9NYW2] synonym: "TRB5" EXACT [UniProtKB:Q9NYW2] xref: EMBL:AAF43907.1 xref: EMBL:AAH69084.1 xref: EMBL:AAH69551.1 xref: EMBL:AAH96701.1 xref: EMBL:AAH96735.1 xref: EMBL:AAH98353.1 xref: EMBL:AAU21137.1 xref: UniProtKB:Q4KN29 xref: UniProtKB:Q645Y2 xref: UniProtKB:Q9NYW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020117 ! TAS2R8_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058981 name: TA2R7_HUMAN def: "Taste receptor type 2 member 7" [UniProtKB:Q9NYW3] synonym: "T2R7" EXACT [UniProtKB:Q9NYW3] synonym: "Taste receptor family B member 4" EXACT [UniProtKB:Q9NYW3] synonym: "TRB4" EXACT [UniProtKB:Q9NYW3] xref: EMBL:AAF43906.1 xref: EMBL:AAH69091.1 xref: EMBL:AAH93992.1 xref: EMBL:AAI13562.1 xref: EMBL:AAU21138.1 xref: UniProtKB:Q645Y1 xref: UniProtKB:Q9NYW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020116 ! TAS2R7_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058982 name: TA2R4_HUMAN def: "Taste receptor type 2 member 4" [UniProtKB:Q9NYW5] synonym: "T2R4" EXACT [UniProtKB:Q9NYW5] xref: EMBL:AAF43904.1 xref: EMBL:AAS02039.1 xref: EMBL:AAU21154.1 xref: UniProtKB:Q645W5 xref: UniProtKB:Q75MV8 xref: UniProtKB:Q9NYW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020115 ! TAS2R4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058983 name: TA2R3_HUMAN def: "Taste receptor type 2 member 3" [UniProtKB:Q9NYW6] synonym: "T2R3" EXACT [UniProtKB:Q9NYW6] xref: EMBL:AAF43903.1 xref: EMBL:AAH69337.1 xref: EMBL:AAH95523.1 xref: EMBL:AAS02038.1 xref: EMBL:AAU21157.1 xref: UniProtKB:Q645W2 xref: UniProtKB:Q75MV6 xref: UniProtKB:Q9NYW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020114 ! TAS2R3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0071074 ! TA2R3_HUMAN-Phosphotyrosine246 [Term] id: CCO:B0058984 name: TA2R1_HUMAN def: "Taste receptor type 2 member 1" [UniProtKB:Q9NYW7] synonym: "T2R1" EXACT [UniProtKB:Q9NYW7] synonym: "Taste receptor family B member 7" EXACT [UniProtKB:Q9NYW7] synonym: "TRB7" EXACT [UniProtKB:Q9NYW7] xref: EMBL:AAF43902.1 xref: EMBL:AAI01730.1 xref: EMBL:AAI01732.1 xref: EMBL:AAU21051.1 xref: UniProtKB:Q646G8 xref: UniProtKB:Q9NYW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020113 ! TAS2R1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001979 ! taste receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058985 name: RBAK_HUMAN def: "RB-associated KRAB zinc finger protein" [UniProtKB:Q9NYW8] synonym: "hRBaK" EXACT [UniProtKB:Q9NYW8] synonym: "RB-associated KRAB repressor" EXACT [UniProtKB:Q9NYW8] synonym: "Zinc finger protein 769" EXACT [UniProtKB:Q9NYW8] xref: EMBL:AAF43389.1 xref: EMBL:AAQ93364.1 xref: EMBL:BAF85758.1 xref: EMBL:EAW87321.1 xref: UniProtKB:A6NDF2 xref: UniProtKB:A8KAK4 xref: UniProtKB:Q9NYW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019645 ! RBAK_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058986 name: CALY_HUMAN def: "Neuron-specific vesicular protein calcyon" [UniProtKB:Q9NYX4] xref: EMBL:AAF34714.1 xref: EMBL:AAH38978.1 xref: EMBL:CAH70279.1 xref: EMBL:CAH70280.1 xref: EMBL:CAH70281.1 xref: EMBL:EAW61334.1 xref: UniProtKB:Q5VWX3 xref: UniProtKB:Q5VWY5 xref: UniProtKB:Q5VWY6 xref: UniProtKB:Q9NYX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022086 ! CALY_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway relationship: participates_in CCO:P0002557 ! positive regulation of endocytosis relationship: transforms_into CCO:B0065817 ! CALY_HUMAN-Phosphotyrosine151 [Term] id: CCO:B0058987 name: IL20_HUMAN def: "Interleukin-20 precursor" [UniProtKB:Q9NYY1] synonym: "Four alpha helix cytokine Zcyto10" EXACT [UniProtKB:Q9NYY1] synonym: "IL-20" EXACT [UniProtKB:Q9NYY1] xref: EMBL:AAF36679.1 xref: EMBL:AAH69311.1 xref: EMBL:AAH69364.1 xref: EMBL:AAH69398.1 xref: EMBL:AAH69425.1 xref: EMBL:AAH69449.1 xref: EMBL:AAH69487.1 xref: EMBL:AAH69523.1 xref: EMBL:AAH69559.1 xref: EMBL:AAH74948.1 xref: EMBL:AAH74949.1 xref: EMBL:AAI17387.1 xref: EMBL:AAI17391.1 xref: EMBL:AAK84423.1 xref: EMBL:AAQ88686.1 xref: UniProtKB:Q17RB3 xref: UniProtKB:Q96QZ6 xref: UniProtKB:Q9NYY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018256 ! IL20_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0006148 ! interleukin-20 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0002082 ! positive regulation of tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002420 ! positive regulation of epidermal cell differentiation relationship: participates_in CCO:P0002432 ! positive regulation of keratinocyte differentiation [Term] id: CCO:B0058988 name: SIGL8_HUMAN def: "Sialic acid-binding Ig-like lectin 8 precursor" [UniProtKB:Q9NYZ4] synonym: "CD329 antigen" EXACT [UniProtKB:Q9NYZ4] synonym: "CDw329" EXACT [UniProtKB:Q9NYZ4] synonym: "SAF-2" EXACT [UniProtKB:Q9NYZ4] synonym: "Sialoadhesin family member 2" EXACT [UniProtKB:Q9NYZ4] synonym: "Siglec-8" EXACT [UniProtKB:Q9NYZ4] xref: EMBL:AAF27622.1 xref: EMBL:AAF34702.1 xref: EMBL:AAG00573.1 xref: EMBL:AAH53319.1 xref: EMBL:AAK55140.1 xref: UniProtKB:Q7Z728 xref: UniProtKB:Q9NYZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019906 ! SIGLEC8_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058989 name: PEN2_HUMAN def: "Gamma-secretase subunit PEN-2" [UniProtKB:Q9NZ42] synonym: "Presenilin enhancer protein 2" EXACT [UniProtKB:Q9NZ42] xref: EMBL:AAF67646.1 xref: EMBL:AAH09575.1 xref: UniProtKB:Q9NZ42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019363 ! PSENEN_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016196 ! tmed10-psen1-4 physical interaction relationship: participates_in CCO:I0017775 ! tmed10-psenen-2 physical interaction relationship: participates_in CCO:I0018565 ! tmed10-psen1-5 physical interaction relationship: participates_in CCO:I0018697 ! tmed10-psen1 physical interaction relationship: participates_in CCO:I0018886 ! tmed10-psenen physical interaction relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0000755 ! Notch receptor processing [Term] id: CCO:B0058990 name: Q9NZ48_HUMAN def: "Uncharacterized hematopoietic stem/progenitor cells protein MDS026" [UniProtKB:Q9NZ48] xref: EMBL:AAF67639.1 xref: UniProtKB:Q9NZ48 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0058991 name: EHF_HUMAN def: "ETS homologous factor" [UniProtKB:Q9NZC4] synonym: "Epithelium-specific Ets transcription factor 3" EXACT [UniProtKB:Q9NZC4] synonym: "ESE-3" EXACT [UniProtKB:Q9NZC4] synonym: "ETS domain-containing transcription factor" EXACT [UniProtKB:Q9NZC4] synonym: "hEHF" EXACT [UniProtKB:Q9NZC4] xref: EMBL:AAD30990.1 xref: EMBL:AAD30991.1 xref: EMBL:AAF06998.1 xref: EMBL:AAF61670.1 xref: EMBL:AAG35644.1 xref: EMBL:AAH38995.1 xref: EMBL:AAW80658.1 xref: EMBL:CAC12700.1 xref: EMBL:CAC12701.1 xref: UniProtKB:Q9H509 xref: UniProtKB:Q9NZC4 xref: UniProtKB:Q9UKF9 xref: UniProtKB:Q9Y5V4 xref: UniProtKB:Q9Y5V5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017668 ! EHF_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064932 ! EHF_HUMAN-Phosphoserine242 [Term] id: CCO:B0058992 name: SMAL1_HUMAN def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1" [UniProtKB:Q9NZC9] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9NZC9] synonym: "HepA-related protein" EXACT [UniProtKB:Q9NZC9] synonym: "hHARP" EXACT [UniProtKB:Q9NZC9] synonym: "Sucrose nonfermenting protein 2-like 1" EXACT [UniProtKB:Q9NZC9] xref: EMBL:AAF24984.1 xref: EMBL:AAF70454.1 xref: EMBL:AAH16482.1 xref: EMBL:AAH43341.1 xref: EMBL:AAL73034.1 xref: EMBL:AAX93097.1 xref: EMBL:BAA90955.1 xref: EMBL:CAB59251.1 xref: EMBL:EAW70567.1 xref: UniProtKB:A6NEH0 xref: UniProtKB:Q53R00 xref: UniProtKB:Q96AY1 xref: UniProtKB:Q9NXQ5 xref: UniProtKB:Q9NZC9 xref: UniProtKB:Q9UFH3 xref: UniProtKB:Q9UI93 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019944 ! SMARCAL1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058993 name: GPC5D_HUMAN def: "G-protein coupled receptor family C group 5 member D" [UniProtKB:Q9NZD1] xref: EMBL:AAF72873.1 xref: EMBL:AAH69341.1 xref: EMBL:AAI07078.1 xref: EMBL:AAI07079.1 xref: EMBL:BAB89342.1 xref: EMBL:BAC79169.1 xref: UniProtKB:Q3KNV3 xref: UniProtKB:Q7Z5J9 xref: UniProtKB:Q8TDS6 xref: UniProtKB:Q9NZD1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017998 ! GPRC5D_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001420 ! sevenless binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058994 name: AHSP_HUMAN def: "Alpha-hemoglobin-stabilizing protein" [UniProtKB:Q9NZD4] synonym: "Erythroid differentiation-related factor" EXACT [UniProtKB:Q9NZD4] synonym: "Erythroid-associated factor" EXACT [UniProtKB:Q9NZD4] xref: EMBL:AAF64279.1 xref: EMBL:AAH35842.1 xref: EMBL:AAK50856.1 xref: EMBL:AAL82894.1 xref: EMBL:AAO49381.1 xref: UniProtKB:Q8TD01 xref: UniProtKB:Q9NZD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016935 ! AHSP_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004445 ! hemoglobin binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000401 ! hemoglobin complex relationship: participates_in CCO:I0019184 ! ahsp-hba1-1 direct interaction relationship: participates_in CCO:P0002964 ! protein stabilization [Term] id: CCO:B0058995 name: SPG21_HUMAN def: "Maspardin" [UniProtKB:Q9NZD8] synonym: "Acid cluster protein 33" EXACT [UniProtKB:Q9NZD8] synonym: "Spastic paraplegia 21 autosomal recessive Mast syndrome protein" EXACT [UniProtKB:Q9NZD8] xref: EMBL:AAF64275.1 xref: EMBL:AAH00244.1 xref: EMBL:AAK14917.1 xref: EMBL:BAD18813.1 xref: UniProtKB:Q6ZMB6 xref: UniProtKB:Q9NZD8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020013 ! SPG21_human relationship: has_function CCO:F0005692 ! CD4 receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: participates_in CCO:I0015044 ! gga2-spg21 physical interaction relationship: participates_in CCO:I0015051 ! c6orf166-spg21 physical interaction relationship: participates_in CCO:I0015130 ! spg21-traf2 physical interaction relationship: participates_in CCO:I0015212 ! rabac1-spg21 physical interaction relationship: participates_in CCO:I0015243 ! ctps2-spg21 physical interaction relationship: participates_in CCO:I0015378 ! mtmr9-spg21 physical interaction relationship: participates_in CCO:I0015461 ! spg21-znf263 physical interaction relationship: participates_in CCO:I0015474 ! prps1-spg21 physical interaction relationship: participates_in CCO:I0015527 ! cutc-spg21 physical interaction relationship: participates_in CCO:I0015602 ! rtn4-spg21 physical interaction relationship: participates_in CCO:P0002969 ! antigen receptor-mediated signaling pathway [Term] id: CCO:B0058996 name: GPC5B_HUMAN def: "G-protein coupled receptor family C group 5 member B precursor" [UniProtKB:Q9NZH0] synonym: "A-69G12.1" EXACT [UniProtKB:Q9NZH0] synonym: "RAIG-2" EXACT [UniProtKB:Q9NZH0] synonym: "Retinoic acid-induced gene 2 protein" EXACT [UniProtKB:Q9NZH0] xref: EMBL:AAC27544.1 xref: EMBL:AAF05331.1 xref: EMBL:AAF67321.1 xref: EMBL:AAH34467.1 xref: EMBL:BAC11414.1 xref: EMBL:CAC00632.1 xref: UniProtKB:O75205 xref: UniProtKB:Q8NBZ8 xref: UniProtKB:Q9NZH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017996 ! GPRC5B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001420 ! sevenless binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0058997 name: GRHL1_HUMAN def: "Grainyhead-like protein 1 homolog" [UniProtKB:Q9NZI5] synonym: "Mammalian grainyhead" EXACT [UniProtKB:Q9NZI5] synonym: "NH32" EXACT [UniProtKB:Q9NZI5] synonym: "Transcription factor CP2-like 2" EXACT [UniProtKB:Q9NZI5] synonym: "Transcription factor LBP-32" EXACT [UniProtKB:Q9NZI5] xref: EMBL:AAF32276.1 xref: EMBL:AAH67519.1 xref: EMBL:AAH67520.1 xref: EMBL:AAH67521.1 xref: EMBL:AAM22616.1 xref: EMBL:AAX93273.1 xref: UniProtKB:A6NLA4 xref: UniProtKB:Q53T93 xref: UniProtKB:Q6NWN7 xref: UniProtKB:Q6NWN8 xref: UniProtKB:Q6NWN9 xref: UniProtKB:Q8NI33 xref: UniProtKB:Q9NZI5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018057 ! GRHL1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0058998 name: TF2L1_HUMAN def: "Transcription factor CP2-like protein 1" [UniProtKB:Q9NZI6] synonym: "CP2-related transcriptional repressor 1" EXACT [UniProtKB:Q9NZI6] synonym: "CRTR-1" EXACT [UniProtKB:Q9NZI6] synonym: "Transcription factor LBP-9" EXACT [UniProtKB:Q9NZI6] xref: EMBL:AAF32275.1 xref: EMBL:AAH64698.1 xref: EMBL:AAX88871.1 xref: UniProtKB:Q4ZG43 xref: UniProtKB:Q9NZI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020240 ! TFCP2L1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0003207 ! general transcriptional repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0058999 name: UBIP1_HUMAN def: "Upstream-binding protein 1" [UniProtKB:Q9NZI7] synonym: "LBP-1" EXACT [UniProtKB:Q9NZI7] xref: EMBL:AAF32274.1 xref: EMBL:AAH47235.1 xref: EMBL:BAB14501.1 xref: EMBL:CAH18658.1 xref: UniProtKB:Q68CT0 xref: UniProtKB:Q86Y57 xref: UniProtKB:Q9H8V0 xref: UniProtKB:Q9NZI7 xref: UniProtKB:Q9UD76 xref: UniProtKB:Q9UD78 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020399 ! UBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0001129 ! negative regulation of transcription [Term] id: CCO:B0059000 name: IF2B1_HUMAN def: "Insulin-like growth factor 2 mRNA-binding protein 1" [UniProtKB:Q9NZI8] synonym: "Coding region determinant-binding protein" EXACT [UniProtKB:Q9NZI8] synonym: "CRD-BP" EXACT [UniProtKB:Q9NZI8] synonym: "IGF-II mRNA-binding protein 1" EXACT [UniProtKB:Q9NZI8] synonym: "IGF2 mRNA-binding protein 1" EXACT [UniProtKB:Q9NZI8] synonym: "IMP-1" EXACT [UniProtKB:Q9NZI8] synonym: "VICKZ family member 1" EXACT [UniProtKB:Q9NZI8] synonym: "Zipcode-binding protein 1" EXACT [UniProtKB:Q9NZI8] xref: EMBL:AAF37203.1 xref: UniProtKB:Q9NZI8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018220 ! IGF2BP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006094 ! translation regulator activity relationship: has_function CCO:F0007303 ! mRNA 5'-UTR binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: transforms_into CCO:B0067007 ! IF2B1_HUMAN-Phosphoserine181 [Term] id: CCO:B0059001 name: MTCH1_HUMAN def: "Mitochondrial carrier homolog 1" [UniProtKB:Q9NZJ7] synonym: "Presenilin-associated protein" EXACT [UniProtKB:Q9NZJ7] xref: EMBL:AAD52644.3 xref: EMBL:AAF07936.1 xref: EMBL:AAF12793.3 xref: EMBL:AAH00702.2 xref: EMBL:AAH06507.1 xref: EMBL:AAH09962.2 xref: EMBL:AAI10915.1 xref: EMBL:AAQ88883.1 xref: EMBL:CAI23305.1 xref: EMBL:CAI23306.1 xref: UniProtKB:Q6PK60 xref: UniProtKB:Q6UX45 xref: UniProtKB:Q7L465 xref: UniProtKB:Q9BW23 xref: UniProtKB:Q9NZJ7 xref: UniProtKB:Q9NZR6 xref: UniProtKB:Q9UJZ5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018673 ! MTCH1_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000673 ! caspase activation relationship: participates_in CCO:P0000884 ! regulation of signal transduction relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0068316 ! MTCH1_HUMAN-Phosphoserine381 [Term] id: CCO:B0059002 name: Q9NZL1_HUMAN def: "Aspartyl protease" [UniProtKB:Q9NZL1] xref: EMBL:AAF35836.1 xref: UniProtKB:Q9NZL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017113 ! BACE2_human relationship: has_function CCO:F0000659 ! aspartic-type endopeptidase activity relationship: has_function CCO:F0000663 ! pepsin A activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0002375 ! aspartic-type signal peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002133 ! negative regulation of amyloid precursor protein biosynthetic process [Term] id: CCO:B0059003 name: Q9NZL2_HUMAN def: "Aspartyl protease" [UniProtKB:Q9NZL2] synonym: "Beta-site APP-cleaving enzyme 2, isoform CRA_a" EXACT [UniProtKB:Q9NZL2] xref: EMBL:AAF35835.1 xref: EMBL:EAX09611.1 xref: UniProtKB:Q9NZL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017113 ! BACE2_human relationship: has_function CCO:F0000659 ! aspartic-type endopeptidase activity relationship: has_function CCO:F0000663 ! pepsin A activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0002375 ! aspartic-type signal peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0002133 ! negative regulation of amyloid precursor protein biosynthetic process [Term] id: CCO:B0059004 name: ZN224_HUMAN def: "Zinc finger protein 224" [UniProtKB:Q9NZL3] synonym: "BMZF-2" EXACT [UniProtKB:Q9NZL3] synonym: "Bone marrow zinc finger 2" EXACT [UniProtKB:Q9NZL3] synonym: "Zinc finger protein 233" EXACT [UniProtKB:Q9NZL3] synonym: "Zinc finger protein 255" EXACT [UniProtKB:Q9NZL3] synonym: "Zinc finger protein 27" EXACT [UniProtKB:Q9NZL3] synonym: "Zinc finger protein KOX22" EXACT [UniProtKB:Q9NZL3] xref: EMBL:AAD32448.1 xref: EMBL:AAF04106.2 xref: EMBL:AAF24968.1 xref: EMBL:AAH51902.1 xref: EMBL:AAN61121.1 xref: EMBL:CAA36579.1 xref: UniProtKB:A6NFW9 xref: UniProtKB:P17033 xref: UniProtKB:Q86V10 xref: UniProtKB:Q8IZC8 xref: UniProtKB:Q9NZL3 xref: UniProtKB:Q9UID9 xref: UniProtKB:Q9Y2P6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020664 ! ZNF224_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072069 ! ZN224_HUMAN-Phosphoserine245 [Term] id: CCO:B0059005 name: IRPL1_HUMAN def: "X-linked interleukin-1 receptor accessory protein-like 1 precursor" [UniProtKB:Q9NZN1] synonym: "IL1RAPL-1" EXACT [UniProtKB:Q9NZN1] synonym: "Oligophrenin-4" EXACT [UniProtKB:Q9NZN1] synonym: "Three immunoglobulin domain-containing IL-1 receptor-related 2" EXACT [UniProtKB:Q9NZN1] synonym: "TIGIRR-2" EXACT [UniProtKB:Q9NZN1] xref: EMBL:AAF59411.1 xref: EMBL:AAG21369.1 xref: EMBL:BAC81119.1 xref: EMBL:CAB56046.1 xref: UniProtKB:Q9NZN1 xref: UniProtKB:Q9UJ53 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018316 ! IL1RAPL1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059006 name: ARHGC_HUMAN def: "Rho guanine nucleotide exchange factor 12" [UniProtKB:Q9NZN5] synonym: "Leukemia-associated RhoGEF" EXACT [UniProtKB:Q9NZN5] xref: EMBL:AAF36817.1 xref: EMBL:AAH63117.1 xref: EMBL:BAA20836.2 xref: UniProtKB:O15086 xref: UniProtKB:Q6P526 xref: UniProtKB:Q9NZN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017021 ! ARHGEF12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018359 ! abca1-arhgef12 physical interaction relationship: participates_in CCO:I0018704 ! arhgef12-rhoa-1 direct interaction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0063549 ! ARHGC_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0063550 ! ARHGC_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0063551 ! ARHGC_HUMAN-Phosphothreonine736 relationship: transforms_into CCO:B0063552 ! ARHGC_HUMAN-Phosphoserine1288 [Term] id: CCO:B0059007 name: OR6C3_HUMAN def: "Olfactory receptor 6C3" [UniProtKB:Q9NZP0] synonym: "HSA8" EXACT [UniProtKB:Q9NZP0] xref: EMBL:AAF40353.1 xref: UniProtKB:Q9NZP0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019200 ! OR6C3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059008 name: OR6C2_HUMAN def: "Olfactory receptor 6C2" [UniProtKB:Q9NZP2] synonym: "HSA3" EXACT [UniProtKB:Q9NZP2] xref: EMBL:AAF40351.1 xref: UniProtKB:Q9NZP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019199 ! OR6C2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059009 name: RABJ_HUMAN def: "Rab and DnaJ domain-containing protein" [UniProtKB:Q9NZQ0] xref: EMBL:AAF44347.1 xref: EMBL:AAH34049.1 xref: EMBL:AAM22521.1 xref: EMBL:CAI46214.1 xref: EMBL:DAA01323.1 xref: EMBL:EAX00735.1 xref: EMBL:EAX00736.1 xref: EMBL:EAX00737.1 xref: UniProtKB:Q5JV88 xref: UniProtKB:Q86Y24 xref: UniProtKB:Q9NZQ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019610 ! RBJ_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0059010 name: SPN90_HUMAN def: "SH3 adapter protein SPIN90" [UniProtKB:Q9NZQ3] synonym: "AF3p21" EXACT [UniProtKB:Q9NZQ3] synonym: "Dia-interacting protein 1" EXACT [UniProtKB:Q9NZQ3] synonym: "Diaphanous protein-interacting protein" EXACT [UniProtKB:Q9NZQ3] synonym: "DIP-1" EXACT [UniProtKB:Q9NZQ3] synonym: "NCK-interacting protein with SH3 domain" EXACT [UniProtKB:Q9NZQ3] synonym: "SH3 protein interacting with Nck, 90 kDa" EXACT [UniProtKB:Q9NZQ3] synonym: "VacA-interacting protein, 54 kDa" EXACT [UniProtKB:Q9NZQ3] synonym: "VIP54" EXACT [UniProtKB:Q9NZQ3] xref: EMBL:AAF35985.1 xref: EMBL:AAK09094.1 xref: EMBL:BAB63204.1 xref: EMBL:BAB63205.1 xref: EMBL:CAB65089.2 xref: UniProtKB:Q9NZQ3 xref: UniProtKB:Q9UGM8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020017 ! NCKIPSD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070801 ! SPN90_HUMAN-Phosphothreonine181 [Term] id: CCO:B0059011 name: PD1L1_HUMAN def: "Programmed cell death 1 ligand 1 precursor" [UniProtKB:Q9NZQ7] synonym: "B7 homolog 1" EXACT [UniProtKB:Q9NZQ7] synonym: "B7-H1" EXACT [UniProtKB:Q9NZQ7] synonym: "CD274 antigen" EXACT [UniProtKB:Q9NZQ7] synonym: "PD-L1" EXACT [UniProtKB:Q9NZQ7] synonym: "PDCD1 ligand 1" EXACT [UniProtKB:Q9NZQ7] synonym: "Programmed death ligand 1" EXACT [UniProtKB:Q9NZQ7] xref: EMBL:AAF25807.1 xref: EMBL:AAG18508.1 xref: EMBL:AAH69381.1 xref: EMBL:AAH74984.1 xref: EMBL:AAI13735.1 xref: EMBL:AAI13737.1 xref: EMBL:AAP13470.1 xref: EMBL:AAP42144.1 xref: EMBL:AAU09634.1 xref: EMBL:BAA91966.1 xref: EMBL:CAI15983.1 xref: UniProtKB:Q14CJ2 xref: UniProtKB:Q66RK1 xref: UniProtKB:Q6WEX4 xref: UniProtKB:Q9NUZ5 xref: UniProtKB:Q9NZQ7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019326 ! CD274_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation [Term] id: CCO:B0059012 name: TMOD2_HUMAN def: "Tropomodulin-2" [UniProtKB:Q9NZR1] synonym: "N-Tmod" EXACT [UniProtKB:Q9NZR1] synonym: "Neuronal tropomodulin" EXACT [UniProtKB:Q9NZR1] xref: EMBL:AAF31668.1 xref: EMBL:AAH64961.1 xref: UniProtKB:Q9NZR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020293 ! TMOD2_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001654 ! tropomyosin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:P0002533 ! positive regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059013 name: VSX1_HUMAN def: "Visual system homeobox 1" [UniProtKB:Q9NZR4] synonym: "Homeodomain protein RINX" EXACT [UniProtKB:Q9NZR4] synonym: "Retinal inner nuclear layer homeobox protein" EXACT [UniProtKB:Q9NZR4] synonym: "Transcription factor VSX1" EXACT [UniProtKB:Q9NZR4] xref: EMBL:AAF37425.2 xref: EMBL:AAF99656.1 xref: EMBL:AAF99657.1 xref: EMBL:AAI26229.1 xref: EMBL:ABI23973.1 xref: EMBL:CAI18918.1 xref: UniProtKB:Q0GM65 xref: UniProtKB:Q5TF40 xref: UniProtKB:Q5TF41 xref: UniProtKB:Q9HCU3 xref: UniProtKB:Q9NU27 xref: UniProtKB:Q9NZR4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020465 ! VSX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059014 name: KLRF1_HUMAN def: "Killer cell lectin-like receptor subfamily F member 1" [UniProtKB:Q9NZS2] synonym: "Activating coreceptor NKp80" EXACT [UniProtKB:Q9NZS2] synonym: "Lectin-like receptor F1" EXACT [UniProtKB:Q9NZS2] xref: EMBL:AAF37804.1 xref: EMBL:AAF37805.1 xref: EMBL:AAH98354.1 xref: EMBL:AAL14873.1 xref: EMBL:AAL14874.1 xref: EMBL:CAC29425.1 xref: UniProtKB:Q4KMT5 xref: UniProtKB:Q96PR2 xref: UniProtKB:Q96PR3 xref: UniProtKB:Q9NZS1 xref: UniProtKB:Q9NZS2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018429 ! KLRF1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0004977 ! MHC class I receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0059015 name: BFAR_HUMAN def: "Bifunctional apoptosis regulator" [UniProtKB:Q9NZS9] synonym: "RING finger protein 47" EXACT [UniProtKB:Q9NZS9] xref: EMBL:AAF59975.1 xref: EMBL:AAH03054.1 xref: UniProtKB:Q9NZS9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017144 ! BFAR_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0063873 ! BFAR_HUMAN-Phosphoserine376 [Term] id: CCO:B0059016 name: CALL5_HUMAN def: "Calmodulin-like protein 5" [UniProtKB:Q9NZT1] synonym: "Calmodulin-like skin protein" EXACT [UniProtKB:Q9NZT1] xref: EMBL:AAF66821.1 xref: EMBL:AAH39172.1 xref: EMBL:CAI11030.1 xref: UniProtKB:Q5SQI3 xref: UniProtKB:Q8IXU8 xref: UniProtKB:Q9NZT1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017218 ! CALML5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064057 ! CALL5_HUMAN-N-acetylalanine2 [Term] id: CCO:B0059017 name: OGFR_HUMAN def: "Opioid growth factor receptor" [UniProtKB:Q9NZT2] synonym: "7-60 protein" EXACT [UniProtKB:Q9NZT2] synonym: "OGFr" EXACT [UniProtKB:Q9NZT2] synonym: "Zeta-type opioid receptor" EXACT [UniProtKB:Q9NZT2] xref: EMBL:AAD03737.1 xref: EMBL:AAD03745.1 xref: EMBL:AAF64404.1 xref: EMBL:AAF64405.1 xref: EMBL:AAF64406.1 xref: EMBL:AAH14137.1 xref: EMBL:BAB15775.1 xref: EMBL:CAC28882.1 xref: EMBL:CAI95763.1 xref: UniProtKB:O96029 xref: UniProtKB:Q4VXW5 xref: UniProtKB:Q96CM2 xref: UniProtKB:Q9BQW1 xref: UniProtKB:Q9H4H0 xref: UniProtKB:Q9H7J5 xref: UniProtKB:Q9NZT2 xref: UniProtKB:Q9NZT3 xref: UniProtKB:Q9NZT4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019041 ! OGFR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0068962 ! OGFR_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0068963 ! OGFR_HUMAN-Phosphoserine349 relationship: transforms_into CCO:B0068964 ! OGFR_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0068965 ! OGFR_HUMAN-Phosphoserine378 relationship: transforms_into CCO:B0068966 ! OGFR_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0068967 ! OGFR_HUMAN-Phosphoserine484 [Term] id: CCO:B0059018 name: LMCD1_HUMAN def: "LIM and cysteine-rich domains protein 1" [UniProtKB:Q9NZU5] synonym: "Dyxin" EXACT [UniProtKB:Q9NZU5] xref: EMBL:AAF34411.1 xref: EMBL:AAG36778.1 xref: EMBL:AAH00646.1 xref: EMBL:BAB13976.1 xref: UniProtKB:Q9NZU5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018508 ! LMCD1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0059019 name: CABP3_HUMAN def: "Calcium-binding protein 3" [UniProtKB:Q9NZU6] synonym: "CaBP3" EXACT [UniProtKB:Q9NZU6] xref: EMBL:AAF25792.1 xref: EMBL:AAF27810.1 xref: EMBL:AAF27811.1 xref: UniProtKB:Q9NYY0 xref: UniProtKB:Q9NZT9 xref: UniProtKB:Q9NZU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017204 ! CABP3_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059020 name: CRIM1_HUMAN def: "Cysteine-rich motor neuron 1 protein precursor" [UniProtKB:Q9NZV1] synonym: "CRIM-1" EXACT [UniProtKB:Q9NZV1] synonym: "Cysteine-rich repeat-containing protein S52" EXACT [UniProtKB:Q9NZV1] xref: EMBL:AAF34409.1 xref: EMBL:AAG37011.1 xref: EMBL:AAI11990.1 xref: EMBL:AAI13372.1 xref: EMBL:AAQ88737.1 xref: EMBL:BAD92376.1 xref: UniProtKB:Q2M2G4 xref: UniProtKB:Q59GH0 xref: UniProtKB:Q7LCQ5 xref: UniProtKB:Q9H318 xref: UniProtKB:Q9NZV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017458 ! CRIM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: transforms_into CCO:B0064467 ! CRIM1_HUMAN-Phosphothreonine1035 [Term] id: CCO:B0059021 name: ZIM2_HUMAN def: "Zinc finger imprinted 2" [UniProtKB:Q9NZV7] xref: EMBL:AAF61478.1 xref: EMBL:AAI04877.1 xref: EMBL:AAI04879.1 xref: UniProtKB:Q2M3K1 xref: UniProtKB:Q9NZV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020606 ! ZIM2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059022 name: Q9NZX6_HUMAN def: "HSPC060" [UniProtKB:Q9NZX6] xref: EMBL:AAF29032.1 xref: UniProtKB:Q9NZX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:B0059023 name: CHMP5_HUMAN def: "Charged multivesicular body protein 5" [UniProtKB:Q9NZZ3] synonym: "Chromatin-modifying protein 5" EXACT [UniProtKB:Q9NZZ3] synonym: "hVps60" EXACT [UniProtKB:Q9NZZ3] synonym: "SNF7 domain-containing protein 2" EXACT [UniProtKB:Q9NZZ3] synonym: "Vacuolar protein-sorting-associated protein 60" EXACT [UniProtKB:Q9NZZ3] synonym: "Vps60" EXACT [UniProtKB:Q9NZZ3] xref: EMBL:AAD27743.1 xref: EMBL:AAF29140.1 xref: EMBL:AAF42917.1 xref: EMBL:AAG23821.1 xref: EMBL:AAH06974.1 xref: EMBL:AAH07457.1 xref: EMBL:AAH16698.1 xref: EMBL:AAH20796.1 xref: EMBL:AAH21168.1 xref: EMBL:CAH72744.1 xref: UniProtKB:Q5VXW2 xref: UniProtKB:Q96AV2 xref: UniProtKB:Q9HB68 xref: UniProtKB:Q9NYS4 xref: UniProtKB:Q9NZZ3 xref: UniProtKB:Q9Y323 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017356 ! CHMP5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015702 ! appbp2-chmp5 physical interaction relationship: participates_in CCO:P0000491 ! regulation of receptor recycling relationship: transforms_into CCO:B0064354 ! CHMP5_HUMAN-Phosphoserine219 [Term] id: CCO:B0059024 name: CNIH4_HUMAN def: "Protein cornichon homolog 4" [UniProtKB:Q9P003] xref: EMBL:AAF29127.1 xref: EMBL:AAH00573.1 xref: EMBL:CAB66864.1 xref: UniProtKB:Q9H0X8 xref: UniProtKB:Q9P003 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017403 ! CNIH4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059025 name: TAP26_HUMAN def: "Thyroid transcription factor 1-associated protein 26" [UniProtKB:Q9P031] synonym: "Coiled-coil domain-containing protein 59" EXACT [UniProtKB:Q9P031] synonym: "TTF-1-associated protein 26" EXACT [UniProtKB:Q9P031] synonym: "TTF-1-associated protein BR2" EXACT [UniProtKB:Q9P031] xref: EMBL:AAF29092.1 xref: EMBL:AAG43569.1 xref: EMBL:AAH20647.1 xref: EMBL:BAA91524.1 xref: UniProtKB:Q9H2V5 xref: UniProtKB:Q9NW62 xref: UniProtKB:Q9P031 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020148 ! CCDC59_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059026 name: PTAD1_HUMAN def: "Protein tyrosine phosphatase-like protein PTPLAD1" [UniProtKB:Q9P035] synonym: "B-ind1" EXACT [UniProtKB:Q9P035] synonym: "Butyrate-induced protein 1" EXACT [UniProtKB:Q9P035] synonym: "hB-ind1" EXACT [UniProtKB:Q9P035] synonym: "Protein-tyrosine phosphatase-like A domain-containing protein 1" EXACT [UniProtKB:Q9P035] xref: EMBL:AAF29085.1 xref: EMBL:AAH19873.1 xref: EMBL:AAH35508.1 xref: EMBL:AAH47685.1 xref: EMBL:AAH58912.1 xref: EMBL:ABB83547.1 xref: EMBL:BAB55101.1 xref: EMBL:BAC11249.1 xref: EMBL:BAC11277.1 xref: EMBL:CAB69070.1 xref: UniProtKB:A0PJA1 xref: UniProtKB:Q280Z3 xref: UniProtKB:Q6PD63 xref: UniProtKB:Q8IUI5 xref: UniProtKB:Q8NC86 xref: UniProtKB:Q8NCB1 xref: UniProtKB:Q96T12 xref: UniProtKB:Q9NQA7 xref: UniProtKB:Q9P035 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019536 ! PTPLAD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017040 ! tnfrsf1b-q9p035 physical interaction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001131 ! Rac protein signal transduction relationship: transforms_into CCO:B0069587 ! PTAD1_HUMAN-Phosphoserine114 [Term] id: CCO:B0059027 name: Q9P0G0_HUMAN def: "HSPC076" [UniProtKB:Q9P0G0] xref: EMBL:AAF28899.1 xref: UniProtKB:Q9P0G0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059028 name: NDUAD_HUMAN def: "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13" [UniProtKB:Q9P0J0] synonym: "Cell death regulatory protein GRIM-19" EXACT [UniProtKB:Q9P0J0] synonym: "CI-B16.6" EXACT [UniProtKB:Q9P0J0] synonym: "Complex I-B16.6" EXACT [UniProtKB:Q9P0J0] synonym: "Gene associated with retinoic-interferon-induced mortality 19 protein" EXACT [UniProtKB:Q9P0J0] synonym: "GRIM-19" EXACT [UniProtKB:Q9P0J0] synonym: "NADH-ubiquinone oxidoreductase B16.6 subunit" EXACT [UniProtKB:Q9P0J0] xref: EMBL:AAD27748.1 xref: EMBL:AAF67481.1 xref: EMBL:AAG28167.1 xref: EMBL:AAG44670.1 xref: EMBL:AAH00589.2 xref: EMBL:AAH09189.1 xref: UniProtKB:Q6PKI0 xref: UniProtKB:Q9H2L3 xref: UniProtKB:Q9P0J0 xref: UniProtKB:Q9Y327 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018743 ! NDUFA13_human relationship: has_function CCO:F0000447 ! NADH dehydrogenase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0001250 ! apoptotic nuclear changes relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068550 ! NDUAD_HUMAN-N-acetylalanine2 [Term] id: CCO:B0059029 name: VAPA_HUMAN def: "Vesicle-associated membrane protein-associated protein A" [UniProtKB:Q9P0L0] synonym: "33 kDa Vamp-associated protein" EXACT [UniProtKB:Q9P0L0] synonym: "VAMP-A" EXACT [UniProtKB:Q9P0L0] synonym: "VAMP-associated protein A" EXACT [UniProtKB:Q9P0L0] synonym: "VAP-33" EXACT [UniProtKB:Q9P0L0] synonym: "VAP-A" EXACT [UniProtKB:Q9P0L0] xref: EMBL:AAC26508.1 xref: EMBL:AAD09742.1 xref: EMBL:AAD13576.1 xref: EMBL:AAF72105.1 xref: EMBL:AAH02992.2 xref: EMBL:AAV38424.1 xref: UniProtKB:O75453 xref: UniProtKB:Q5U0E7 xref: UniProtKB:Q9P0L0 xref: UniProtKB:Q9UBZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020432 ! VAPA_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001374 ! vesicle relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0059030 name: ZN167_HUMAN def: "Zinc finger protein 167" [UniProtKB:Q9P0L1] synonym: "ZFP" EXACT [UniProtKB:Q9P0L1] synonym: "Zinc finger protein 448" EXACT [UniProtKB:Q9P0L1] synonym: "Zinc finger protein 64" EXACT [UniProtKB:Q9P0L1] synonym: "Zinc finger protein with KRAB and SCAN domains 7" EXACT [UniProtKB:Q9P0L1] xref: EMBL:AAF72104.1 xref: EMBL:AAH10555.1 xref: EMBL:AAH63020.1 xref: EMBL:AAQ16302.1 xref: UniProtKB:Q6WL09 xref: UniProtKB:Q96FQ2 xref: UniProtKB:Q9P0L1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020637 ! ZNF167_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015080 ! nfic-znf167 physical interaction relationship: participates_in CCO:I0015498 ! znf167-znf434 physical interaction relationship: participates_in CCO:I0015544 ! scand1-znf167 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059031 name: IL17C_HUMAN def: "Interleukin-17C precursor" [UniProtKB:Q9P0M4] synonym: "Cytokine CX2" EXACT [UniProtKB:Q9P0M4] synonym: "IL-17C" EXACT [UniProtKB:Q9P0M4] xref: EMBL:AAF28105.1 xref: EMBL:AAG27921.1 xref: EMBL:AAH69152.1 xref: EMBL:AAI01836.1 xref: EMBL:AAI12197.1 xref: EMBL:AAQ88835.1 xref: UniProtKB:Q3MIG8 xref: UniProtKB:Q9HC75 xref: UniProtKB:Q9P0M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018251 ! IL17C_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0059032 name: H2AW_HUMAN def: "Core histone macro-H2A.2" [UniProtKB:Q9P0M6] synonym: "Histone macroH2A2" EXACT [UniProtKB:Q9P0M6] synonym: "mH2A2" EXACT [UniProtKB:Q9P0M6] xref: EMBL:AAF72101.1 xref: EMBL:AAH16172.1 xref: EMBL:AAK52471.1 xref: EMBL:BAB14239.1 xref: EMBL:CAI13683.1 xref: UniProtKB:Q5SQT2 xref: UniProtKB:Q9P0M6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018098 ! H2AFY2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000183 ! Barr body relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: participates_in CCO:P0000803 ! dosage compensation [Term] id: CCO:B0059033 name: TBCD7_HUMAN def: "TBC1 domain family member 7" [UniProtKB:Q9P0N9] xref: EMBL:AAF36159.1 xref: EMBL:AAH07054.1 xref: UniProtKB:Q9P0N9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020182 ! TBC1D7_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059034 name: CXXC1_HUMAN def: "CpG-binding protein" [UniProtKB:Q9P0U4] synonym: "CXXC-type zinc finger protein 1" EXACT [UniProtKB:Q9P0U4] synonym: "PHD finger and CXXC domain-containing protein 1" EXACT [UniProtKB:Q9P0U4] xref: EMBL:AAF37799.1 xref: EMBL:AAH14940.1 xref: EMBL:AAH15733.1 xref: EMBL:AAH29922.1 xref: EMBL:BAA96307.1 xref: EMBL:CAB66796.1 xref: UniProtKB:Q8N2W4 xref: UniProtKB:Q96BC8 xref: UniProtKB:Q9P0U4 xref: UniProtKB:Q9P2V7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017506 ! CXXC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019171 ! tbp-cxxc1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064605 ! CXXC1_HUMAN-Phosphoserine224 relationship: transforms_into CCO:B0064606 ! CXXC1_HUMAN-Phosphothreonine227 [Term] id: CCO:B0059035 name: CAC1I_HUMAN def: "Voltage-dependent T-type calcium channel subunit alpha-1I" [UniProtKB:Q9P0X4] synonym: "Ca(v)3.3" EXACT [UniProtKB:Q9P0X4] synonym: "Voltage-gated calcium channel subunit alpha Cav3.3" EXACT [UniProtKB:Q9P0X4] xref: EMBL:AAD45251.1 xref: EMBL:AAF25722.1 xref: EMBL:AAF44626.1 xref: EMBL:AAM67414.1 xref: EMBL:BAA86434.1 xref: EMBL:CAI17903.1 xref: EMBL:CAI19180.1 xref: EMBL:CAI19662.1 xref: UniProtKB:O95504 xref: UniProtKB:Q5JZ88 xref: UniProtKB:Q7Z6S9 xref: UniProtKB:Q8NFX6 xref: UniProtKB:Q9NZC8 xref: UniProtKB:Q9P0X4 xref: UniProtKB:Q9UH15 xref: UniProtKB:Q9UH30 xref: UniProtKB:Q9ULU9 xref: UniProtKB:Q9UNE6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017209 ! CACNA1I_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001513 ! voltage-gated calcium channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001841 ! low voltage-gated calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000448 ! voltage-gated calcium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059036 name: GMIP_HUMAN def: "GEM-interacting protein" [UniProtKB:Q9P107] synonym: "GMIP" EXACT [UniProtKB:Q9P107] xref: EMBL:AAF61330.1 xref: EMBL:AAI26437.1 xref: EMBL:EAW84839.1 xref: UniProtKB:A0AVN9 xref: UniProtKB:Q9P107 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017940 ! GMIP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0066476 ! GMIP_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0066477 ! GMIP_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0066478 ! GMIP_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0066479 ! GMIP_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0066480 ! GMIP_HUMAN-Phosphoserine441 relationship: transforms_into CCO:B0066481 ! GMIP_HUMAN-Phosphoserine914 relationship: transforms_into CCO:B0066482 ! GMIP_HUMAN-Phosphoserine919 relationship: transforms_into CCO:B0066483 ! GMIP_HUMAN-Phosphoserine923 [Term] id: CCO:B0059037 name: CLC1B_HUMAN def: "C-type lectin domain family 1 member B" [UniProtKB:Q9P126] synonym: "C-type lectin-like receptor 2" EXACT [UniProtKB:Q9P126] synonym: "CLEC-2" EXACT [UniProtKB:Q9P126] xref: EMBL:AAF36777.1 xref: EMBL:AAH29554.1 xref: EMBL:AAQ88962.1 xref: UniProtKB:Q6UWX7 xref: UniProtKB:Q8NHR6 xref: UniProtKB:Q9P126 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017376 ! CLEC1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0064377 ! CLC1B_HUMAN-Phosphotyrosine7 [Term] id: CCO:B0059038 name: TAAR3_HUMAN def: "Putative trace amine-associated receptor 3" [UniProtKB:Q9P1P4] synonym: "G-protein coupled receptor 57" EXACT [UniProtKB:Q9P1P4] xref: EMBL:AAF27279.1 xref: UniProtKB:Q9P1P4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020122 ! TAAR3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059039 name: TAAR2_HUMAN def: "Trace amine-associated receptor 2" [UniProtKB:Q9P1P5] synonym: "G-protein coupled receptor 58" EXACT [UniProtKB:Q9P1P5] xref: EMBL:AAF27278.1 xref: EMBL:AAH67461.1 xref: EMBL:AAH67462.1 xref: EMBL:AAH67463.1 xref: EMBL:AAV70122.1 xref: EMBL:AAV70150.1 xref: EMBL:CAH72103.1 xref: UniProtKB:Q5QD02 xref: UniProtKB:Q6NWS1 xref: UniProtKB:Q6NWS2 xref: UniProtKB:Q6NWS3 xref: UniProtKB:Q9P1P5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020121 ! TAAR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059040 name: OR1A1_HUMAN def: "Olfactory receptor 1A1" [UniProtKB:Q9P1Q5] synonym: "Olfactory receptor 17-7" EXACT [UniProtKB:Q9P1Q5] synonym: "Olfactory receptor OR17-11" EXACT [UniProtKB:Q9P1Q5] synonym: "OR17-7" EXACT [UniProtKB:Q9P1Q5] xref: EMBL:AAF37311.1 xref: EMBL:AAI41936.1 xref: EMBL:AAK95040.1 xref: EMBL:DAA04639.1 xref: EMBL:EAW90520.1 xref: UniProtKB:A5D914 xref: UniProtKB:Q6IFM1 xref: UniProtKB:Q96R87 xref: UniProtKB:Q9P1Q5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019057 ! OR1A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059041 name: Q9P1T0_HUMAN def: "AS12 protein" [UniProtKB:Q9P1T0] xref: EMBL:AAF35254.1 xref: UniProtKB:Q9P1T0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059042 name: Q9P1T1_HUMAN def: "AS11 protein" [UniProtKB:Q9P1T1] xref: EMBL:AAF35253.1 xref: UniProtKB:Q9P1T1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000030 ! two-component response regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059043 name: MDFIC_HUMAN def: "MyoD family inhibitor domain-containing protein" [UniProtKB:Q9P1T7] synonym: "HIC" EXACT [UniProtKB:Q9P1T7] synonym: "I-mfa domain-containing protein" EXACT [UniProtKB:Q9P1T7] xref: EMBL:AAF36998.1 xref: EMBL:AAF36999.1 xref: EMBL:AAP33842.1 xref: UniProtKB:Q9P1T6 xref: UniProtKB:Q9P1T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018595 ! MDFIC_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004391 ! cyclin binding relationship: has_function CCO:F0004610 ! Tat protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002910 ! positive regulation of viral transcription relationship: transforms_into CCO:B0068108 ! MDFIC_HUMAN-Phosphoserine249 relationship: transforms_into CCO:B0068109 ! MDFIC_HUMAN-Phosphoserine252 [Term] id: CCO:B0059044 name: Q9P1V4_HUMAN xref: UniProtKB:Q9P1V4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059045 name: SIRPG_HUMAN def: "Signal-regulatory protein gamma precursor" [UniProtKB:Q9P1W8] synonym: "CD172 antigen-like family member B" EXACT [UniProtKB:Q9P1W8] synonym: "CD172g antigen" EXACT [UniProtKB:Q9P1W8] synonym: "Signal-regulatory protein beta-2" EXACT [UniProtKB:Q9P1W8] synonym: "SIRP-b2" EXACT [UniProtKB:Q9P1W8] synonym: "SIRP-beta-2" EXACT [UniProtKB:Q9P1W8] xref: EMBL:AAH20629.2 xref: EMBL:AAH64532.1 xref: EMBL:AAV88530.1 xref: EMBL:AAV88531.1 xref: EMBL:BAA95692.1 xref: EMBL:CAC00474.1 xref: EMBL:CAI16692.2 xref: EMBL:CAM23420.1 xref: EMBL:CAM28283.1 xref: EMBL:CAM28285.1 xref: UniProtKB:Q5D051 xref: UniProtKB:Q5JV25 xref: UniProtKB:Q5MKL4 xref: UniProtKB:Q8WWA5 xref: UniProtKB:Q9NQK8 xref: UniProtKB:Q9P1W8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019911 ! SIRPG_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: participates_in CCO:P0001239 ! positive regulation of cell-cell adhesion relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation [Term] id: CCO:B0059046 name: ZBTB4_HUMAN def: "Zinc finger and BTB domain-containing protein 4" [UniProtKB:Q9P1Z0] synonym: "KAISO-L1" EXACT [UniProtKB:Q9P1Z0] synonym: "KAISO-like zinc finger protein 1" EXACT [UniProtKB:Q9P1Z0] xref: EMBL:AAH33259.1 xref: EMBL:AAH43352.1 xref: EMBL:AAP59447.1 xref: EMBL:BAA96062.2 xref: UniProtKB:Q7Z697 xref: UniProtKB:Q86XJ4 xref: UniProtKB:Q8N4V8 xref: UniProtKB:Q9P1Z0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011782 ! ZBTB4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059047 name: CACO1_HUMAN def: "Calcium-binding and coiled-coil domain-containing protein 1" [UniProtKB:Q9P1Z2] synonym: "Calphoglin" EXACT [UniProtKB:Q9P1Z2] synonym: "Coiled-coil coactivator protein" EXACT [UniProtKB:Q9P1Z2] synonym: "Sarcoma antigen NY-SAR-3" EXACT [UniProtKB:Q9P1Z2] xref: EMBL:AAH03177.1 xref: EMBL:AAO65163.1 xref: EMBL:AAQ15251.1 xref: EMBL:AAQ88763.1 xref: EMBL:AAT68474.1 xref: EMBL:BAA96060.1 xref: EMBL:BAB55428.1 xref: EMBL:CAB66829.1 xref: EMBL:CAG38598.1 xref: EMBL:EAW96728.1 xref: UniProtKB:Q6FI59 xref: UniProtKB:Q71RC3 xref: UniProtKB:Q86WF8 xref: UniProtKB:Q96JU3 xref: UniProtKB:Q9H090 xref: UniProtKB:Q9P1Z2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017211 ! CALCOCO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: transforms_into CCO:B0064046 ! CACO1_HUMAN-Phosphoserine563 [Term] id: CCO:B0059048 name: PLCE1_HUMAN def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1" [UniProtKB:Q9P212] synonym: "EC 3.1.4.11" EXACT [UniProtKB:Q9P212] synonym: "Pancreas-enriched phospholipase C" EXACT [UniProtKB:Q9P212] synonym: "Phosphoinositide-specific phospholipase C epsilon-1" EXACT [UniProtKB:Q9P212] synonym: "Phospholipase C-epsilon-1" EXACT [UniProtKB:Q9P212] synonym: "PLC-epsilon-1" EXACT [UniProtKB:Q9P212] xref: EMBL:AAF22005.1 xref: EMBL:AAG17145.2 xref: EMBL:AAG28341.1 xref: EMBL:AAY45890.1 xref: EMBL:BAA96040.2 xref: EMBL:BAB14090.1 xref: EMBL:CAH70739.1 xref: EMBL:CAH73288.1 xref: EMBL:CAH73757.1 xref: EMBL:CAI16674.1 xref: EMBL:EAW50043.1 xref: UniProtKB:A6NLA1 xref: UniProtKB:Q1X6H8 xref: UniProtKB:Q5VWL5 xref: UniProtKB:Q9H9X8 xref: UniProtKB:Q9HBX6 xref: UniProtKB:Q9HC53 xref: UniProtKB:Q9P212 xref: UniProtKB:Q9UHV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019433 ! PLCE1_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003512 ! Ras GTPase binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000466 ! regulation of cell growth relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000715 ! epidermal growth factor receptor signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0000782 ! Ras protein signal transduction relationship: participates_in CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002698 ! regulation of Ras protein signal transduction relationship: participates_in CCO:P0002762 ! inositol phosphate-mediated signaling [Term] id: CCO:B0059049 name: POGK_HUMAN def: "Pogo transposable element with KRAB domain" [UniProtKB:Q9P215] xref: EMBL:AAM12422.1 xref: EMBL:BAA96037.1 xref: UniProtKB:Q8TE07 xref: UniProtKB:Q9P215 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019466 ! POGK_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0069434 ! POGK_HUMAN-Phosphoserine534 [Term] id: CCO:B0059050 name: DAPLE_HUMAN def: "Protein Daple" [UniProtKB:Q9P219] synonym: "Coiled-coil domain-containing protein 88C" EXACT [UniProtKB:Q9P219] synonym: "Dvl-associating protein with a high frequency of leucine residues" EXACT [UniProtKB:Q9P219] synonym: "hDaple" EXACT [UniProtKB:Q9P219] synonym: "HkRP2" EXACT [UniProtKB:Q9P219] synonym: "Hook-related protein 2" EXACT [UniProtKB:Q9P219] xref: EMBL:AAH28565.2 xref: EMBL:AAH35914.1 xref: EMBL:BAA96033.2 xref: EMBL:CAD62629.1 xref: EMBL:CAH10602.1 xref: UniProtKB:Q69YK1 xref: UniProtKB:Q7L1M2 xref: UniProtKB:Q86SX7 xref: UniProtKB:Q8IYG8 xref: UniProtKB:Q9P219 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017522 ! CCDC88C_human relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_function CCO:F0005879 ! protein self-association relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000246 ! insoluble fraction relationship: participates_in CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001483 ! protein destabilization relationship: transforms_into CCO:B0064630 ! DAPLE_HUMAN-Phosphoserine1806 [Term] id: CCO:B0059051 name: RHG23_HUMAN def: "Rho GTPase-activating protein 23" [UniProtKB:Q9P227] synonym: "Rho-type GTPase-activating protein 23" EXACT [UniProtKB:Q9P227] xref: EMBL:BAA96025.1 xref: UniProtKB:Q9P227 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019723 ! ARHGAP23_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069974 ! RHG23_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0069975 ! RHG23_HUMAN-Phosphoserine372 relationship: transforms_into CCO:B0069976 ! RHG23_HUMAN-Phosphoserine423 [Term] id: CCO:B0059052 name: ZFAT_HUMAN def: "Zinc finger protein ZFAT" [UniProtKB:Q9P243] synonym: "Zinc finger protein 406" EXACT [UniProtKB:Q9P243] xref: EMBL:AAH25423.1 xref: EMBL:AAH46180.1 xref: EMBL:AAI01767.1 xref: EMBL:AAI01769.1 xref: EMBL:BAA96009.1 xref: EMBL:BAD12567.1 xref: EMBL:BAD12568.1 xref: EMBL:BAD12569.1 xref: EMBL:BAD12570.1 xref: UniProtKB:Q3MIM5 xref: UniProtKB:Q6PJ01 xref: UniProtKB:Q75PJ6 xref: UniProtKB:Q75PJ7 xref: UniProtKB:Q75PJ9 xref: UniProtKB:Q86X64 xref: UniProtKB:Q9P243 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022801 ! ZFAT_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059053 name: ZN492_HUMAN def: "Zinc finger protein 492" [UniProtKB:Q9P255] xref: EMBL:AAI10576.1 xref: EMBL:BAA95997.1 xref: UniProtKB:Q08EI7 xref: UniProtKB:Q08EI8 xref: UniProtKB:Q9P255 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020776 ! ZNF492_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059054 name: PAK7_HUMAN def: "Serine/threonine-protein kinase PAK 7" [UniProtKB:Q9P286] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9P286] synonym: "p21-activated kinase 7" EXACT [UniProtKB:Q9P286] synonym: "PAK-5" EXACT [UniProtKB:Q9P286] synonym: "PAK-7" EXACT [UniProtKB:Q9P286] xref: EMBL:BAA86578.1 xref: EMBL:BAA94194.1 xref: EMBL:CAH71126.1 xref: EMBL:CAI23529.1 xref: EMBL:CAI42211.1 xref: UniProtKB:Q5W115 xref: UniProtKB:Q9BX09 xref: UniProtKB:Q9P286 xref: UniProtKB:Q9ULF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006030 ! PAK7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: transforms_into CCO:B0069076 ! PAK7_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0069077 ! PAK7_HUMAN-Phosphothreonine107 [Term] id: CCO:B0059055 name: C5ARL_HUMAN def: "C5a anaphylatoxin chemotactic receptor C5L2" [UniProtKB:Q9P296] synonym: "G-protein coupled receptor 77" EXACT [UniProtKB:Q9P296] xref: EMBL:AAH67478.1 xref: EMBL:AAK12640.1 xref: EMBL:AAP23197.1 xref: EMBL:BAA95414.1 xref: UniProtKB:Q9P296 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017199 ! GPR77_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0064025 ! C5ARL_HUMAN-Phosphoserine326 [Term] id: CCO:B0059056 name: CHD7_HUMAN def: "Chromodomain-helicase-DNA-binding protein 7" [UniProtKB:Q9P2D1] synonym: "ATP-dependent helicase CHD7" EXACT [UniProtKB:Q9P2D1] synonym: "CHD-7" EXACT [UniProtKB:Q9P2D1] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9P2D1] xref: EMBL:AAH14681.1 xref: EMBL:AAH51264.1 xref: EMBL:AAH53890.1 xref: EMBL:AAH68000.1 xref: EMBL:AAH80627.1 xref: EMBL:AAI10819.1 xref: EMBL:BAA91113.1 xref: EMBL:BAA91116.1 xref: EMBL:BAA92654.1 xref: UniProtKB:Q05DI5 xref: UniProtKB:Q2TAN4 xref: UniProtKB:Q66K35 xref: UniProtKB:Q7Z6C0 xref: UniProtKB:Q7Z7Q2 xref: UniProtKB:Q9NXA0 xref: UniProtKB:Q9NXA3 xref: UniProtKB:Q9P2D1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017352 ! CHD7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064328 ! CHD7_HUMAN-Phosphoserine2254 relationship: transforms_into CCO:B0064329 ! CHD7_HUMAN-Phosphoserine2255 relationship: transforms_into CCO:B0064330 ! CHD7_HUMAN-Phosphothreonine2350 relationship: transforms_into CCO:B0064331 ! CHD7_HUMAN-Phosphoserine2356 relationship: transforms_into CCO:B0064332 ! CHD7_HUMAN-Phosphoserine2533 relationship: transforms_into CCO:B0064333 ! CHD7_HUMAN-Phosphoserine2559 [Term] id: CCO:B0059057 name: ZN319_HUMAN def: "Zinc finger protein 319" [UniProtKB:Q9P2F9] xref: EMBL:AAH93919.1 xref: EMBL:AAI01768.1 xref: EMBL:BAA92626.1 xref: UniProtKB:Q52LH8 xref: UniProtKB:Q9P2F9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020701 ! ZNF319_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059058 name: RCOR3_HUMAN def: "REST corepressor 3" [UniProtKB:Q9P2K3] xref: EMBL:AAH31608.1 xref: EMBL:BAA91872.1 xref: EMBL:BAA92581.1 xref: EMBL:CAH72432.1 xref: EMBL:CAH72433.1 xref: EMBL:CAH73871.1 xref: EMBL:CAH73872.1 xref: UniProtKB:Q5VT47 xref: UniProtKB:Q7L9I5 xref: UniProtKB:Q8N5U3 xref: UniProtKB:Q9NV83 xref: UniProtKB:Q9P2K3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019661 ! RCOR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069846 ! RCOR3_HUMAN-Phosphoserine156 [Term] id: CCO:B0059059 name: E2AK4_HUMAN def: "Eukaryotic translation initiation factor 2-alpha kinase 4" [UniProtKB:Q9P2K8] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9P2K8] synonym: "GCN2-like protein" EXACT [UniProtKB:Q9P2K8] xref: EMBL:AAH09350.2 xref: EMBL:AAH78179.1 xref: EMBL:BAA92576.1 xref: EMBL:BAB15625.1 xref: EMBL:CAB58360.1 xref: EMBL:CAB70849.1 xref: EMBL:CAB75678.1 xref: EMBL:CAH10626.1 xref: UniProtKB:Q69YL7 xref: UniProtKB:Q6DC97 xref: UniProtKB:Q96GN6 xref: UniProtKB:Q9H5K1 xref: UniProtKB:Q9NSQ3 xref: UniProtKB:Q9NSZ5 xref: UniProtKB:Q9P2K8 xref: UniProtKB:Q9UJ56 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017650 ! EIF2AK4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015263 ! eif2ak4-ewsr1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0064911 ! E2AK4_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0064912 ! E2AK4_HUMAN-Phosphothreonine667 relationship: transforms_into CCO:B0064913 ! E2AK4_HUMAN-Phosphothreonine899 relationship: transforms_into CCO:B0064914 ! E2AK4_HUMAN-Phosphothreonine904 [Term] id: CCO:B0059060 name: TBC14_HUMAN def: "TBC1 domain family member 14" [UniProtKB:Q9P2M4] xref: EMBL:AAH41167.1 xref: EMBL:BAA92560.1 xref: EMBL:CAD38726.1 xref: UniProtKB:Q8IW15 xref: UniProtKB:Q8NDK3 xref: UniProtKB:Q9P2M4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020159 ! TBC1D14_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059061 name: GBG13_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 precursor" [UniProtKB:Q9P2W3] xref: EMBL:AAH93760.1 xref: EMBL:AAH95525.1 xref: EMBL:AAK40269.1 xref: EMBL:AAK61257.1 xref: EMBL:AAM12594.1 xref: EMBL:BAA92768.1 xref: EMBL:CAB53059.2 xref: UniProtKB:Q52LX0 xref: UniProtKB:Q9P2W3 xref: UniProtKB:Q9UJJ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017883 ! GNG13_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0059062 name: IMPCT_HUMAN def: "Protein IMPACT" [UniProtKB:Q9P2X3] synonym: "Imprinted and ancient gene protein homolog" EXACT [UniProtKB:Q9P2X3] xref: EMBL:AAG23917.1 xref: EMBL:AAG35736.1 xref: EMBL:AAH34016.1 xref: EMBL:AAH36074.1 xref: EMBL:BAA95160.1 xref: EMBL:BAF85222.1 xref: EMBL:EAX01186.1 xref: UniProtKB:A8MXG0 xref: UniProtKB:Q49AM0 xref: UniProtKB:Q9H2X4 xref: UniProtKB:Q9P2X3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018278 ! IMPACT_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0059063 name: ZN219_HUMAN def: "Zinc finger protein 219" [UniProtKB:Q9P2Y4] xref: EMBL:AAH00694.1 xref: EMBL:AAH36105.1 xref: EMBL:BAA90526.1 xref: UniProtKB:Q8IYC1 xref: UniProtKB:Q9BW28 xref: UniProtKB:Q9P2Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020660 ! ZNF219_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072068 ! ZN219_HUMAN-Phosphoserine175 [Term] id: CCO:B0059064 name: POK7_HUMAN def: "HERV-K_1q23.3 provirus ancestral Pol protein" [UniProtKB:Q9QC07] synonym: "HERV-K(C1a) Pol protein" EXACT [UniProtKB:Q9QC07] synonym: "HERV-K110 Pol protein" EXACT [UniProtKB:Q9QC07] synonym: "HERV-K18 Pol protein" EXACT [UniProtKB:Q9QC07] xref: EMBL:AAL60056.1 xref: EMBL:AAS46612.1 xref: EMBL:CAB56603.1 xref: UniProtKB:Q6QAI9 xref: UniProtKB:Q96PI5 xref: UniProtKB:Q9QC07 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0059065 name: MBD2_HUMAN def: "Methyl-CpG-binding domain protein 2" [UniProtKB:Q9UBB5] synonym: "Demethylase" EXACT [UniProtKB:Q9UBB5] synonym: "DMTase" EXACT [UniProtKB:Q9UBB5] synonym: "Methyl-CpG-binding protein MBD2" EXACT [UniProtKB:Q9UBB5] xref: EMBL:AAC68871.1 xref: EMBL:AAC68875.1 xref: EMBL:AAD56596.1 xref: EMBL:AAD56597.1 xref: EMBL:AAH32638.1 xref: UniProtKB:O95242 xref: UniProtKB:Q9UBB5 xref: UniProtKB:Q9UIS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018578 ! MBD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017738 ! mbd2-p66a physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001129 ! negative regulation of transcription relationship: transforms_into CCO:B0068041 ! MBD2_HUMAN-Phosphoserine181 relationship: transforms_into CCO:B0068042 ! MBD2_HUMAN-Phosphoserine407 [Term] id: CCO:B0059066 name: GALP_HUMAN def: "Galanin-like peptide precursor" [UniProtKB:Q9UBC7] xref: EMBL:AAF19724.1 xref: EMBL:AAF19725.1 xref: EMBL:AAQ99038.1 xref: UniProtKB:A1KXL3 xref: UniProtKB:Q9UBC7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017860 ! GALP_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0059067 name: HSFX1_HUMAN def: "Heat shock transcription factor, X-linked" [UniProtKB:Q9UBD0] xref: EMBL:AAD45879.1 xref: EMBL:AAD45880.1 xref: EMBL:AAH21706.1 xref: EMBL:EAW99371.1 xref: UniProtKB:Q9UBD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018165 ! HSFX1_human relationship: encoded_by CCO:G0018166 ! HSFX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018906 ! a2bp1-lw_1 physical interaction relationship: participates_in CCO:I0018956 ! atxn1-lw_1 physical interaction relationship: participates_in CCO:I0019001 ! atxn1-lw_1-1 physical interaction relationship: participates_in CCO:I0019048 ! atxn1-lw_1-2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059068 name: XCL2_HUMAN def: "Cytokine SCM-1 beta precursor" [UniProtKB:Q9UBD3] synonym: "C motif chemokine 2" EXACT [UniProtKB:Q9UBD3] synonym: "XC chemokine ligand 2" EXACT [UniProtKB:Q9UBD3] xref: EMBL:AAH69360.1 xref: EMBL:AAH70308.1 xref: EMBL:BAA09858.1 xref: EMBL:CAB46689.1 xref: UniProtKB:Q9UBD3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020507 ! XCL2_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059069 name: CLCF1_HUMAN def: "Cardiotrophin-like cytokine factor 1 precursor" [UniProtKB:Q9UBD9] synonym: "B cell-stimulating factor 3" EXACT [UniProtKB:Q9UBD9] synonym: "BSF-3" EXACT [UniProtKB:Q9UBD9] synonym: "NNT-1" EXACT [UniProtKB:Q9UBD9] synonym: "Novel neurotrophin-1" EXACT [UniProtKB:Q9UBD9] xref: EMBL:AAD54284.1 xref: EMBL:AAF00991.1 xref: EMBL:AAF00992.1 xref: EMBL:AAH12939.1 xref: EMBL:AAH66229.1 xref: EMBL:AAH66230.1 xref: EMBL:AAH66231.1 xref: EMBL:AAL15436.1 xref: UniProtKB:Q6NZA4 xref: UniProtKB:Q9UBD9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017382 ! CLCF1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000776 ! JAK-STAT cascade relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002082 ! positive regulation of tyrosine phosphorylation of Stat3 protein relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:B0059070 name: NLK_HUMAN def: "Serine/threonine kinase NLK" [UniProtKB:Q9UBE8] synonym: "EC 2.7.11.24" EXACT [UniProtKB:Q9UBE8] synonym: "Nemo-like kinase" EXACT [UniProtKB:Q9UBE8] synonym: "Protein LAK1" EXACT [UniProtKB:Q9UBE8] xref: EMBL:AAD56013.1 xref: EMBL:AAF04857.1 xref: EMBL:AAH64663.1 xref: EMBL:ABC40748.1 xref: UniProtKB:Q2PNI9 xref: UniProtKB:Q6P2A3 xref: UniProtKB:Q9UBE8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018803 ! NLK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017373 ! tak1-stat3-4 physical interaction relationship: participates_in CCO:I0017667 ! myb-nlk physical interaction relationship: participates_in CCO:I0018059 ! tak1-stat3-5 physical interaction relationship: participates_in CCO:I0018060 ! tak1-stat3-6 physical interaction relationship: participates_in CCO:I0019052 ! atxn1-nlk physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0068738 ! NLK_HUMAN-Phosphothreonine286 relationship: transforms_into CCO:B0068739 ! NLK_HUMAN-Phosphothreonine291 relationship: transforms_into CCO:B0068740 ! NLK_HUMAN-Phosphotyrosine293 [Term] id: CCO:B0059071 name: RBX2_HUMAN def: "RING-box protein 2" [UniProtKB:Q9UBF6] synonym: "CKBBP1" EXACT [UniProtKB:Q9UBF6] synonym: "CKII beta-binding protein 1" EXACT [UniProtKB:Q9UBF6] synonym: "Rbx2" EXACT [UniProtKB:Q9UBF6] synonym: "Regulator of cullins 2" EXACT [UniProtKB:Q9UBF6] synonym: "RING finger protein 7" EXACT [UniProtKB:Q9UBF6] synonym: "Sensitive to apoptosis gene protein" EXACT [UniProtKB:Q9UBF6] xref: EMBL:AAD25962.1 xref: EMBL:AAD30147.1 xref: EMBL:AAD55984.1 xref: EMBL:AAH05966.1 xref: EMBL:AAH08627.1 xref: EMBL:AAK37450.1 xref: EMBL:AAP36012.1 xref: UniProtKB:Q9BXN8 xref: UniProtKB:Q9UBF6 xref: UniProtKB:Q9Y5M7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019652 ! RNF7_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0014970 ! itm2c-rnf7 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000838 ! induction of apoptosis by oxidative stress relationship: transforms_into CCO:B0069834 ! RBX2_HUMAN-Phosphothreonine10 [Term] id: CCO:B0059072 name: PI4KB_HUMAN def: "Phosphatidylinositol 4-kinase beta" [UniProtKB:Q9UBF8] synonym: "EC 2.7.1.67" EXACT [UniProtKB:Q9UBF8] synonym: "NPIK" EXACT [UniProtKB:Q9UBF8] synonym: "PI4K-beta" EXACT [UniProtKB:Q9UBF8] synonym: "PI4K92" EXACT [UniProtKB:Q9UBF8] synonym: "PI4Kbeta" EXACT [UniProtKB:Q9UBF8] synonym: "PtdIns 4-kinase beta" EXACT [UniProtKB:Q9UBF8] xref: EMBL:AAC51156.1 xref: EMBL:AAH00029.1 xref: EMBL:AAH40300.1 xref: EMBL:BAA21661.1 xref: EMBL:CAA09495.1 xref: EMBL:CAA09496.1 xref: EMBL:CAH70324.1 xref: UniProtKB:O15096 xref: UniProtKB:P78405 xref: UniProtKB:Q5VWC1 xref: UniProtKB:Q9BWR6 xref: UniProtKB:Q9UBF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019394 ! PI4KB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002761 ! phosphoinositide-mediated signaling relationship: transforms_into CCO:B0069298 ! PI4KB_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0069299 ! PI4KB_HUMAN-Phosphothreonine263 relationship: transforms_into CCO:B0069300 ! PI4KB_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0069301 ! PI4KB_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0069302 ! PI4KB_HUMAN-Phosphoserine294 relationship: transforms_into CCO:B0069303 ! PI4KB_HUMAN-Phosphoserine428 relationship: transforms_into CCO:B0069304 ! PI4KB_HUMAN-Phosphothreonine438 relationship: transforms_into CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: transforms_into CCO:B0069306 ! PI4KB_HUMAN-Phosphothreonine517 relationship: transforms_into CCO:B0069307 ! PI4KB_HUMAN-Phosphothreonine519 [Term] id: CCO:B0059073 name: RBPJL_HUMAN def: "Recombining binding protein suppressor of hairless-like protein" [UniProtKB:Q9UBG7] synonym: "Transcription factor RBP-L" EXACT [UniProtKB:Q9UBG7] xref: EMBL:BAA86121.1 xref: EMBL:BAA87051.1 xref: EMBL:BAA88232.1 xref: EMBL:CAI21080.1 xref: UniProtKB:O95723 xref: UniProtKB:Q5QPU9 xref: UniProtKB:Q9UBG7 xref: UniProtKB:Q9ULV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019650 ! RBPJL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059074 name: XPR1_HUMAN def: "Xenotropic and polytropic retrovirus receptor 1" [UniProtKB:Q9UBH6] synonym: "Protein SYG1 homolog" EXACT [UniProtKB:Q9UBH6] synonym: "X-receptor" EXACT [UniProtKB:Q9UBH6] synonym: "Xenotropic and polytropic murine leukemia virus receptor X3" EXACT [UniProtKB:Q9UBH6] xref: EMBL:AAD08928.1 xref: EMBL:AAD10196.1 xref: EMBL:AAD17211.1 xref: EMBL:AAH41142.1 xref: EMBL:CAB61383.1 xref: EMBL:CAB70825.1 xref: EMBL:CAH70457.1 xref: EMBL:CAH70458.1 xref: EMBL:CAH74089.1 xref: EMBL:CAH74090.1 xref: EMBL:CAH74113.1 xref: EMBL:CAH74114.1 xref: EMBL:EAW91086.1 xref: UniProtKB:O95719 xref: UniProtKB:Q7L8K9 xref: UniProtKB:Q8IW20 xref: UniProtKB:Q9NT19 xref: UniProtKB:Q9UBH6 xref: UniProtKB:Q9UFB9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020510 ! XPR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: transforms_into CCO:B0071892 ! XPR1_HUMAN-Phosphoserine666 relationship: transforms_into CCO:B0071893 ! XPR1_HUMAN-Phosphoserine668 relationship: transforms_into CCO:B0071894 ! XPR1_HUMAN-Phosphothreonine690 [Term] id: CCO:B0059075 name: GBG12_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor" [UniProtKB:Q9UBI6] xref: EMBL:AAF04571.1 xref: EMBL:AAF17220.1 xref: EMBL:AAH05940.1 xref: EMBL:AAK53385.1 xref: EMBL:AAM12593.1 xref: UniProtKB:Q9BRV5 xref: UniProtKB:Q9UBI6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017882 ! GNG12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: transforms_into CCO:B0066397 ! GBG12_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066398 ! GBG12_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0066399 ! GBG12_HUMAN-Phosphotyrosine42 [Term] id: CCO:B0059076 name: P2RX2_HUMAN def: "P2X purinoceptor 2" [UniProtKB:Q9UBL9] synonym: "ATP receptor" EXACT [UniProtKB:Q9UBL9] synonym: "P2X2" EXACT [UniProtKB:Q9UBL9] synonym: "Purinergic receptor" EXACT [UniProtKB:Q9UBL9] xref: EMBL:AAD42947.1 xref: EMBL:AAD42948.1 xref: EMBL:AAF19170.1 xref: EMBL:AAF19171.1 xref: EMBL:AAF19172.1 xref: EMBL:AAF19173.1 xref: EMBL:AAF19174.1 xref: EMBL:AAF74201.1 xref: EMBL:AAF74202.1 xref: EMBL:AAF74203.1 xref: EMBL:AAF74204.1 xref: EMBL:AAQ54329.1 xref: UniProtKB:A6NGB4 xref: UniProtKB:A6NH93 xref: UniProtKB:A6NHC2 xref: UniProtKB:A6NHU3 xref: UniProtKB:A6NIG9 xref: UniProtKB:Q6V9R6 xref: UniProtKB:Q9NR37 xref: UniProtKB:Q9NR38 xref: UniProtKB:Q9UBL9 xref: UniProtKB:Q9UHD5 xref: UniProtKB:Q9UHD6 xref: UniProtKB:Q9UHD7 xref: UniProtKB:Q9Y637 xref: UniProtKB:Q9Y638 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019259 ! P2RX2_human relationship: has_function CCO:F0000165 ! purinergic nucleotide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001273 ! ATP-gated cation channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002733 ! ligand-gated ion channel activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002968 ! positive regulation of calcium-mediated signaling [Term] id: CCO:B0059077 name: PEMT_HUMAN def: "Phosphatidylethanolamine N-methyltransferase" [UniProtKB:Q9UBM1] synonym: "EC 2.1.1.17" EXACT [UniProtKB:Q9UBM1] synonym: "PEAMT" EXACT [UniProtKB:Q9UBM1] synonym: "PEMT" EXACT [UniProtKB:Q9UBM1] synonym: "PEMT2" EXACT [UniProtKB:Q9UBM1] xref: EMBL:AAD53291.1 xref: EMBL:AAD53292.1 xref: EMBL:AAF14867.1 xref: EMBL:AAK19172.1 xref: EMBL:BAA82407.1 xref: UniProtKB:Q9UBM1 xref: UniProtKB:Q9UHY6 xref: UniProtKB:Q9Y6V9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019362 ! PEMT_human relationship: has_function CCO:F0000987 ! phosphatidylethanolamine N-methyltransferase activity relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001757 ! N-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059078 name: DHCR7_HUMAN def: "7-dehydrocholesterol reductase" [UniProtKB:Q9UBM7] synonym: "7-DHC reductase" EXACT [UniProtKB:Q9UBM7] synonym: "EC 1.3.1.21" EXACT [UniProtKB:Q9UBM7] synonym: "Putative sterol reductase SR-2" EXACT [UniProtKB:Q9UBM7] synonym: "Sterol Delta(7)-reductase" EXACT [UniProtKB:Q9UBM7] xref: EMBL:AAC05086.1 xref: EMBL:AAC18345.1 xref: EMBL:AAD02816.1 xref: EMBL:AAD09766.1 xref: EMBL:AAD24762.1 xref: EMBL:AAH00054.1 xref: UniProtKB:O60492 xref: UniProtKB:O60717 xref: UniProtKB:Q9UBM7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017574 ! DHCR7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006901 ! 7-dehydrocholesterol reductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000257 ! nuclear outer membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002045 ! regulation of cell proliferation [Term] id: CCO:B0059079 name: TR10D_HUMAN def: "Tumor necrosis factor receptor superfamily member 10D precursor" [UniProtKB:Q9UBN6] synonym: "CD264 antigen" EXACT [UniProtKB:Q9UBN6] synonym: "DcR2" EXACT [UniProtKB:Q9UBN6] synonym: "Decoy receptor 2" EXACT [UniProtKB:Q9UBN6] synonym: "TNF-related apoptosis-inducing ligand receptor 4" EXACT [UniProtKB:Q9UBN6] synonym: "TRAIL receptor 4" EXACT [UniProtKB:Q9UBN6] synonym: "TRAIL receptor with a truncated death domain" EXACT [UniProtKB:Q9UBN6] synonym: "TRAIL-R4" EXACT [UniProtKB:Q9UBN6] xref: EMBL:AAC32765.1 xref: EMBL:AAC32766.1 xref: EMBL:AAC52053.1 xref: EMBL:AAD03477.1 xref: EMBL:AAH52270.1 xref: EMBL:AAQ88652.1 xref: UniProtKB:Q9UBN6 xref: UniProtKB:Q9Y6Q4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020337 ! TNFRSF10D_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059080 name: DKK3_HUMAN def: "Dickkopf-related protein 3 precursor" [UniProtKB:Q9UBP4] synonym: "Dickkopf-3" EXACT [UniProtKB:Q9UBP4] synonym: "Dkk-3" EXACT [UniProtKB:Q9UBP4] synonym: "hDkk-3" EXACT [UniProtKB:Q9UBP4] xref: EMBL:AAF02676.1 xref: EMBL:AAH07660.1 xref: EMBL:AAQ88744.1 xref: EMBL:BAA85488.1 xref: EMBL:BAA87044.2 xref: EMBL:BAA90548.1 xref: EMBL:BAB84360.1 xref: EMBL:BAB84361.1 xref: UniProtKB:Q9UBP4 xref: UniProtKB:Q9ULB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017581 ! DKK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0017594 ! ubqln4-dkk3 physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0059081 name: HEY2_HUMAN def: "Hairy/enhancer-of-split related with YRPW motif protein 2" [UniProtKB:Q9UBP5] synonym: "Cardiovascular helix-loop-helix factor 1" EXACT [UniProtKB:Q9UBP5] synonym: "Hairy and enhancer of split-related protein 2" EXACT [UniProtKB:Q9UBP5] synonym: "Hairy-related transcription factor 2" EXACT [UniProtKB:Q9UBP5] synonym: "hCHF1" EXACT [UniProtKB:Q9UBP5] synonym: "HES-related repressor protein 2" EXACT [UniProtKB:Q9UBP5] synonym: "HESR-2" EXACT [UniProtKB:Q9UBP5] synonym: "hHRT2" EXACT [UniProtKB:Q9UBP5] synonym: "Protein gridlock homolog" EXACT [UniProtKB:Q9UBP5] xref: EMBL:AAF20173.1 xref: EMBL:AAF37296.1 xref: EMBL:AAF44781.1 xref: EMBL:AAG31157.1 xref: EMBL:AAH07707.1 xref: EMBL:AAV38870.1 xref: EMBL:AAV38871.1 xref: EMBL:BAA96781.1 xref: EMBL:CAB56839.1 xref: EMBL:CAB87581.1 xref: UniProtKB:Q9UBP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018127 ! HEY2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015624 ! hey2-plscr1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059082 name: CKLF_HUMAN def: "Chemokine-like factor" [UniProtKB:Q9UBR5] synonym: "C32" EXACT [UniProtKB:Q9UBR5] xref: EMBL:AAF06722.1 xref: EMBL:AAF19350.1 xref: EMBL:AAF19599.1 xref: EMBL:AAF19600.1 xref: EMBL:AAF21255.1 xref: EMBL:AAF36144.1 xref: EMBL:AAH04380.1 xref: EMBL:AAQ89358.1 xref: EMBL:AAT70694.1 xref: UniProtKB:Q9UBR5 xref: UniProtKB:Q9UHM7 xref: UniProtKB:Q9UHN8 xref: UniProtKB:Q9UI41 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017371 ! CKLF_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059083 name: RNF14_HUMAN def: "E3 ubiquitin-protein ligase RNF14" [UniProtKB:Q9UBS8] synonym: "Androgen receptor-associated protein 54" EXACT [UniProtKB:Q9UBS8] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9UBS8] synonym: "HFB30" EXACT [UniProtKB:Q9UBS8] synonym: "RING finger protein 14" EXACT [UniProtKB:Q9UBS8] synonym: "Triad2 protein" EXACT [UniProtKB:Q9UBS8] xref: EMBL:AAD21842.1 xref: EMBL:AAI26186.1 xref: EMBL:BAA34792.1 xref: EMBL:BAA78677.1 xref: EMBL:CAG32983.1 xref: UniProtKB:A0AV26 xref: UniProtKB:A6NMR2 xref: UniProtKB:O94793 xref: UniProtKB:Q6IBV0 xref: UniProtKB:Q9UBS8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019759 ! RNF14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070107 ! RNF14_HUMAN-Phosphoserine348 [Term] id: CCO:B0059084 name: DKK4_HUMAN def: "Dickkopf-related protein 4 precursor" [UniProtKB:Q9UBT3] synonym: "Dickkopf-4" EXACT [UniProtKB:Q9UBT3] synonym: "Dkk-4" EXACT [UniProtKB:Q9UBT3] synonym: "hDkk-4" EXACT [UniProtKB:Q9UBT3] xref: EMBL:AAF02677.1 xref: EMBL:AAI07047.1 xref: EMBL:AAI07048.1 xref: EMBL:BAA33438.1 xref: EMBL:BAA33475.1 xref: UniProtKB:Q3KNX0 xref: UniProtKB:Q9UBT3 xref: UniProtKB:Q9Y4C3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017582 ! DKK4_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0059085 name: DKK2_HUMAN def: "Dickkopf-related protein 2 precursor" [UniProtKB:Q9UBU2] synonym: "Dickkopf-2" EXACT [UniProtKB:Q9UBU2] synonym: "Dkk-2" EXACT [UniProtKB:Q9UBU2] synonym: "hDkk-2" EXACT [UniProtKB:Q9UBU2] xref: EMBL:AAF02675.1 xref: EMBL:AAH75077.1 xref: EMBL:AAH75078.1 xref: EMBL:AAI26329.1 xref: EMBL:AAI26331.1 xref: EMBL:AAQ88780.1 xref: EMBL:BAA85465.1 xref: EMBL:BAA87056.1 xref: UniProtKB:A0AVE9 xref: UniProtKB:Q9UBU2 xref: UniProtKB:Q9UIU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017580 ! DKK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway [Term] id: CCO:B0059086 name: SE1L1_HUMAN def: "Protein sel-1 homolog 1 precursor" [UniProtKB:Q9UBV2] synonym: "Sel-1L" EXACT [UniProtKB:Q9UBV2] synonym: "Suppressor of lin-12-like protein 1" EXACT [UniProtKB:Q9UBV2] xref: EMBL:AAF24176.1 xref: EMBL:AAF29413.1 xref: EMBL:AAL40905.1 xref: EMBL:AAQ89014.1 xref: EMBL:BAA87904.1 xref: EMBL:BAA89204.1 xref: UniProtKB:Q6UWT6 xref: UniProtKB:Q9P1T9 xref: UniProtKB:Q9UBV2 xref: UniProtKB:Q9UHK7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019860 ! SEL1L_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016984 ! tnfrsf1a-sel1l physical interaction relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0059087 name: B4GT7_HUMAN def: "Beta-1,4-galactosyltransferase 7" [UniProtKB:Q9UBV7] synonym: "b4Gal-T7" EXACT [UniProtKB:Q9UBV7] synonym: "Beta-1,4-GalTase 7" EXACT [UniProtKB:Q9UBV7] synonym: "Beta4Gal-T7" EXACT [UniProtKB:Q9UBV7] synonym: "EC 2.4.1.-" EXACT [UniProtKB:Q9UBV7] synonym: "UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7" EXACT [UniProtKB:Q9UBV7] synonym: "UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7" EXACT [UniProtKB:Q9UBV7] xref: EMBL:AAF22225.1 xref: EMBL:AAH07317.1 xref: EMBL:AAH62983.1 xref: EMBL:AAH72403.1 xref: EMBL:AAQ88941.1 xref: EMBL:BAA83414.1 xref: EMBL:CAB56424.1 xref: UniProtKB:Q9UBV7 xref: UniProtKB:Q9UHN2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017112 ! B4GALT7_human relationship: has_function CCO:F0001853 ! galactosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006198 ! xylosylprotein 4-beta-galactosyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002783 ! negative regulation of fibroblast proliferation [Term] id: CCO:B0059088 name: ZMYM2_HUMAN def: "Zinc finger MYM-type protein 2" [UniProtKB:Q9UBW7] synonym: "Fused in myeloproliferative disorders protein" EXACT [UniProtKB:Q9UBW7] synonym: "Rearranged in atypical myeloproliferative disorder protein" EXACT [UniProtKB:Q9UBW7] synonym: "Zinc finger protein 198" EXACT [UniProtKB:Q9UBW7] xref: EMBL:AAB88464.1 xref: EMBL:AAC01561.1 xref: EMBL:AAC23591.1 xref: EMBL:AAH36372.1 xref: EMBL:CAA07604.1 xref: EMBL:CAA12204.1 xref: EMBL:CAA73875.1 xref: EMBL:CAH56193.1 xref: EMBL:CAH70133.1 xref: EMBL:CAH71822.1 xref: EMBL:EAX08244.1 xref: UniProtKB:A6NDG0 xref: UniProtKB:A6NI02 xref: UniProtKB:O43212 xref: UniProtKB:O43434 xref: UniProtKB:O60898 xref: UniProtKB:Q5W0Q4 xref: UniProtKB:Q63HP0 xref: UniProtKB:Q8NE39 xref: UniProtKB:Q9H538 xref: UniProtKB:Q9UBW7 xref: UniProtKB:Q9UEU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020615 ! ZMYM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072044 ! ZMYM2_HUMAN-Phosphoserine305 relationship: transforms_into CCO:B0072045 ! ZMYM2_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0072046 ! ZMYM2_HUMAN-Phosphoserine838 relationship: transforms_into CCO:B0072047 ! ZMYM2_HUMAN-Phosphothreonine1376 [Term] id: CCO:B0059089 name: HESX1_HUMAN def: "Homeobox expressed in ES cells 1" [UniProtKB:Q9UBX0] synonym: "hAnf" EXACT [UniProtKB:Q9UBX0] synonym: "Homeobox protein ANF" EXACT [UniProtKB:Q9UBX0] xref: EMBL:AAB39561.1 xref: EMBL:AAB88275.1 xref: EMBL:AAC24523.1 xref: EMBL:AAH69515.1 xref: EMBL:AAH93979.1 xref: EMBL:AAI12090.1 xref: UniProtKB:Q52LC5 xref: UniProtKB:Q99667 xref: UniProtKB:Q9UBX0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018124 ! HESX1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059090 name: DUX4_HUMAN def: "Double homeobox protein 4" [UniProtKB:Q9UBX2] synonym: "Double homeobox protein 10" EXACT [UniProtKB:Q9UBX2] synonym: "Double homeobox protein 4/10" EXACT [UniProtKB:Q9UBX2] xref: EMBL:AAD54067.2 xref: EMBL:AAD54068.2 xref: EMBL:AAK91509.1 xref: UniProtKB:Q9UBX2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017641 ! DUX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059091 name: CLN8_HUMAN def: "Protein CLN8" [UniProtKB:Q9UBY8] xref: EMBL:AAF13115.1 xref: EMBL:AAF13116.1 xref: EMBL:AAF13117.1 xref: EMBL:AAF13118.1 xref: EMBL:AAF13119.1 xref: EMBL:AAH07725.1 xref: EMBL:AAP35698.1 xref: UniProtKB:Q86U71 xref: UniProtKB:Q96I95 xref: UniProtKB:Q9UBY8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017390 ! CLN8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001534 ! ER-Golgi intermediate compartment membrane relationship: participates_in CCO:P0002148 ! negative regulation of apoptosis relationship: participates_in CCO:P0002578 ! negative regulation of proteolysis [Term] id: CCO:B0059092 name: REV1_HUMAN def: "DNA repair protein REV1" [UniProtKB:Q9UBZ9] synonym: "AIBP80" EXACT [UniProtKB:Q9UBZ9] synonym: "Alpha integrin-binding protein 80" EXACT [UniProtKB:Q9UBZ9] synonym: "EC 2.7.7.-" EXACT [UniProtKB:Q9UBZ9] synonym: "Rev1-like terminal deoxycytidyl transferase" EXACT [UniProtKB:Q9UBZ9] xref: EMBL:AAF06731.1 xref: EMBL:AAF18986.1 xref: EMBL:AAK43708.1 xref: EMBL:AAY24314.1 xref: EMBL:BAA92079.1 xref: EMBL:BAB21441.1 xref: EMBL:CAB38231.1 xref: UniProtKB:O95941 xref: UniProtKB:Q53SI7 xref: UniProtKB:Q9C0J4 xref: UniProtKB:Q9NUP2 xref: UniProtKB:Q9UBZ9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019680 ! REV1_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0059093 name: Q9UC05_HUMAN def: "Zinc finger protein 72 (Krueppel-related zinc finger protein)." [UniProtKB:Q9UC05] xref: EMBL:CAC16145.1 xref: UniProtKB:Q9UC05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021274 ! ZNF72_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059094 name: ZNF70_HUMAN def: "Zinc finger protein 70" [UniProtKB:Q9UC06] synonym: "Zinc finger protein N27C7-1" EXACT [UniProtKB:Q9UC06] xref: EMBL:AAH40161.1 xref: EMBL:BAB83033.1 xref: EMBL:CAC16148.1 xref: EMBL:CAG30501.1 xref: UniProtKB:Q9UC06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020981 ! ZNF70_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059095 name: ZNF69_HUMAN def: "Zinc finger protein 69" [UniProtKB:Q9UC07] synonym: "hZNF3" EXACT [UniProtKB:Q9UC07] xref: EMBL:AAH51309.1 xref: EMBL:CAC16147.1 xref: UniProtKB:Q86VA7 xref: UniProtKB:Q9UC07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020980 ! ZNF69_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059096 name: Q9UCY6_HUMAN def: "Orphan nuclear receptor steroidogenic factor 1, SF-1(long terminal repeat-binding protein, ELP)" [UniProtKB:Q9UCY6] xref: UniProtKB:Q9UCY6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059097 name: Q9UD04_HUMAN def: "GHDTA" [UniProtKB:Q9UD04] xref: UniProtKB:Q9UD04 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059098 name: NKX12_HUMAN def: "NK1 transcription factor-related protein 2" [UniProtKB:Q9UD57] synonym: "Homeobox protein SAX-1" EXACT [UniProtKB:Q9UD57] synonym: "NKX-1.1" EXACT [UniProtKB:Q9UD57] xref: UniProtKB:Q9UD57 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018793 ! NKX1-2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059099 name: PPR1B_HUMAN def: "Protein phosphatase 1 regulatory subunit 1B" [UniProtKB:Q9UD71] synonym: "DARPP-32" EXACT [UniProtKB:Q9UD71] synonym: "Dopamine- and cAMP-regulated neuronal phosphoprotein" EXACT [UniProtKB:Q9UD71] xref: EMBL:AAH01519.1 xref: EMBL:AAL59016.1 xref: EMBL:AAM76683.1 xref: EMBL:AAP35094.1 xref: EMBL:AAP35095.1 xref: EMBL:AAP35096.1 xref: EMBL:AAP35097.1 xref: EMBL:AAP35098.1 xref: EMBL:AAP35739.1 xref: EMBL:BAB14931.1 xref: UniProtKB:Q547V9 xref: UniProtKB:Q547W0 xref: UniProtKB:Q9H7G1 xref: UniProtKB:Q9UD71 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019483 ! PPP1R1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020407 ! ppp1r1b-dlgap4 physical interaction relationship: participates_in CCO:I0020630 ! ppp1r1b-robo2 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069461 ! PPR1B_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0069462 ! PPR1B_HUMAN-Phosphothreonine34 relationship: transforms_into CCO:B0069463 ! PPR1B_HUMAN-Phosphothreonine75 relationship: transforms_into CCO:B0069464 ! PPR1B_HUMAN-Phosphoserine198 [Term] id: CCO:B0059100 name: Q9UDC8_HUMAN def: "Reverse transcriptase homolog" [UniProtKB:Q9UDC8] xref: UniProtKB:Q9UDC8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0059101 name: Q9UDC9_HUMAN def: "Reverse transcriptase homolog" [UniProtKB:Q9UDC9] xref: UniProtKB:Q9UDC9 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0059102 name: Q9UDD7_HUMAN def: "G protein-coupled receptor homolog clone H8" [UniProtKB:Q9UDD7] xref: UniProtKB:Q9UDD7 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059103 name: Q9UDF1_HUMAN def: "Fibroblast growth factor receptor 1 THIRD immunoglobulin domain, FGFR 1 IG domain III" [UniProtKB:Q9UDF1] xref: UniProtKB:Q9UDF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001344 ! fibroblast growth factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:B0059104 name: ZN212_HUMAN def: "Zinc finger protein 212" [UniProtKB:Q9UDV6] synonym: "Zinc finger protein C2H2-150" EXACT [UniProtKB:Q9UDV6] xref: EMBL:AAC51296.1 xref: EMBL:AAD45826.2 xref: EMBL:AAH22785.2 xref: UniProtKB:Q13396 xref: UniProtKB:Q8N664 xref: UniProtKB:Q9UDV6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020655 ! ZNF212_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059105 name: ZN282_HUMAN def: "Zinc finger protein 282" [UniProtKB:Q9UDV7] synonym: "HTLV-I U5RE-binding protein 1" EXACT [UniProtKB:Q9UDV7] synonym: "HUB-1" EXACT [UniProtKB:Q9UDV7] xref: EMBL:AAH73805.1 xref: EMBL:BAA24380.1 xref: UniProtKB:O43691 xref: UniProtKB:Q6DKK0 xref: UniProtKB:Q9UDV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020692 ! ZNF282_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072090 ! ZN282_HUMAN-Phosphotyrosine161 [Term] id: CCO:B0059106 name: MALT1_HUMAN def: "Mucosa-associated lymphoid tissue lymphoma translocation protein 1" [UniProtKB:Q9UDY8] synonym: "EC 3.4.22.-" EXACT [UniProtKB:Q9UDY8] synonym: "MALT lymphoma-associated translocation" EXACT [UniProtKB:Q9UDY8] synonym: "Paracaspase" EXACT [UniProtKB:Q9UDY8] xref: EMBL:AAD38507.2 xref: EMBL:AAG38589.1 xref: EMBL:AAH30143.1 xref: EMBL:BAA83099.1 xref: EMBL:CAB70725.1 xref: UniProtKB:Q9NTB7 xref: UniProtKB:Q9UDY8 xref: UniProtKB:Q9ULX4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018561 ! MALT1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004132 ! kinase activator activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_function CCO:F0005879 ! protein self-association relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001453 ! CBM complex relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000769 ! activation of NF-kappaB-inducing kinase activity relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002970 ! T cell receptor signaling pathway relationship: participates_in CCO:P0002988 ! positive regulation of T cell activation relationship: transforms_into CCO:B0067858 ! MALT1_HUMAN-Phosphoserine135 [Term] id: CCO:B0059107 name: CFDP1_HUMAN def: "Craniofacial development protein 1" [UniProtKB:Q9UEE9] synonym: "Bucentaur" EXACT [UniProtKB:Q9UEE9] xref: EMBL:AAH00991.1 xref: EMBL:AAP88821.1 xref: EMBL:BAA20069.1 xref: EMBL:BAA20070.1 xref: EMBL:BAA31860.1 xref: EMBL:BAA31864.1 xref: EMBL:BAA31865.1 xref: EMBL:BAA31867.1 xref: EMBL:CAG46908.1 xref: UniProtKB:O00393 xref: UniProtKB:O00404 xref: UniProtKB:Q9UEE9 xref: UniProtKB:Q9UEF0 xref: UniProtKB:Q9UEF1 xref: UniProtKB:Q9UEF8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017339 ! CFDP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015368 ! cfdp1-ewsr1 physical interaction relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: transforms_into CCO:B0064299 ! CFDP1_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0064300 ! CFDP1_HUMAN-Phosphoserine250 [Term] id: CCO:B0059108 name: KLOT_HUMAN def: "Klotho precursor" [UniProtKB:Q9UEF7] synonym: "EC 3.2.1.31" EXACT [UniProtKB:Q9UEF7] xref: EMBL:BAA23382.1 xref: EMBL:BAA24940.1 xref: EMBL:BAA24941.1 xref: EMBL:CAC94767.1 xref: EMBL:CAC94773.1 xref: EMBL:CAH71888.1 xref: UniProtKB:Q5VZ95 xref: UniProtKB:Q96KV5 xref: UniProtKB:Q96KW5 xref: UniProtKB:Q9UEF7 xref: UniProtKB:Q9UEI9 xref: UniProtKB:Q9Y4F0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018426 ! KL_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds relationship: has_function CCO:F0000950 ! beta-glucuronidase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001637 ! vitamin D binding relationship: has_function CCO:F0001889 ! beta-glucosidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0005808 ! cation binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: transforms_into CCO:B0067386 ! KLOT_HUMAN-Phosphotyrosine497 [Term] id: CCO:B0059109 name: ZN629_HUMAN def: "Zinc finger protein 629" [UniProtKB:Q9UEG4] synonym: "Zinc finger protein 65" EXACT [UniProtKB:Q9UEG4] xref: EMBL:AAA61332.1 xref: EMBL:BAA20784.1 xref: UniProtKB:Q15938 xref: UniProtKB:Q9UEG4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020866 ! ZNF629_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059110 name: VTI1B_HUMAN def: "Vesicle transport through interaction with t-SNAREs homolog 1B" [UniProtKB:Q9UEU0] synonym: "Vesicle transport v-SNARE protein Vti1-like 1" EXACT [UniProtKB:Q9UEU0] synonym: "Vti1-rp1" EXACT [UniProtKB:Q9UEU0] xref: EMBL:AAC52016.1 xref: EMBL:AAC73059.1 xref: EMBL:AAH03142.1 xref: EMBL:AAV38155.1 xref: EMBL:CAG33038.1 xref: EMBL:CAG46892.1 xref: UniProtKB:O43547 xref: UniProtKB:Q96J28 xref: UniProtKB:Q9UEU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020467 ! VTI1B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020568 ! golgb1-vti1b physical interaction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059111 name: Q9UEV7_HUMAN def: "Lymphocyte-specific protein 1" [UniProtKB:Q9UEV7] xref: EMBL:AAC00495.1 xref: UniProtKB:Q9UEV7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018526 ! LSP1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059112 name: Q9UEV8_HUMAN def: "Lymphocyte specific protein 1" [UniProtKB:Q9UEV8] xref: EMBL:AAB99825.1 xref: UniProtKB:Q9UEV8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018526 ! LSP1_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059113 name: MARCO_HUMAN def: "Macrophage receptor MARCO" [UniProtKB:Q9UEW3] synonym: "Macrophage receptor with collagenous structure" EXACT [UniProtKB:Q9UEW3] synonym: "Scavenger receptor class A member 2" EXACT [UniProtKB:Q9UEW3] xref: EMBL:AAC08800.1 xref: EMBL:AAD41064.1 xref: EMBL:AAH16004.1 xref: UniProtKB:Q9UEW3 xref: UniProtKB:Q9Y5S3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018570 ! MARCO_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001365 ! scavenger receptor activity relationship: has_function CCO:F0001838 ! pattern recognition receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0059114 name: ZBT47_HUMAN def: "Zinc finger and BTB domain-containing protein 47" [UniProtKB:Q9UFB7] synonym: "Zinc finger protein 651" EXACT [UniProtKB:Q9UFB7] xref: EMBL:AAH21855.1 xref: EMBL:BAA86504.1 xref: EMBL:CAB61386.2 xref: UniProtKB:Q8WTY8 xref: UniProtKB:Q9UFB7 xref: UniProtKB:Q9ULN0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020562 ! ZBTB47_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059115 name: Q9UFT8_HUMAN def: "Putative uncharacterized protein DKFZp586M0622 (SMAD, mothers against DPP homolog 1 (Drosophila), isoform CRA_b)" [UniProtKB:Q9UFT8] xref: EMBL:CAB55898.1 xref: EMBL:EAX05039.1 xref: UniProtKB:Q9UFT8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021276 ! DKFZp586M0622_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059116 name: TBC29_HUMAN def: "Putative TBC1 domain family member 29" [UniProtKB:Q9UFV1] xref: EMBL:AAH96718.1 xref: EMBL:CAB55896.1 xref: EMBL:EAW51238.1 xref: UniProtKB:Q9UFV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020170 ! TBC1D29_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059117 name: CGBP1_HUMAN def: "CGG triplet repeat-binding protein 1" [UniProtKB:Q9UFW8] synonym: "20 kDa CGG-binding protein" EXACT [UniProtKB:Q9UFW8] synonym: "CGG-binding protein 1" EXACT [UniProtKB:Q9UFW8] synonym: "p20-CGGBP DNA-binding protein" EXACT [UniProtKB:Q9UFW8] xref: EMBL:AAD04161.1 xref: EMBL:AAH52980.1 xref: EMBL:CAA03974.1 xref: EMBL:CAB55894.1 xref: EMBL:CAG33135.1 xref: EMBL:CAL38583.1 xref: UniProtKB:O15183 xref: UniProtKB:Q9UFW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017343 ! CGGBP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064301 ! CGBP1_HUMAN-Phosphoserine164 [Term] id: CCO:B0059118 name: Q9UFY1_HUMAN def: "Putative uncharacterized protein DKFZp434N101" [UniProtKB:Q9UFY1] xref: EMBL:CAB53696.1 xref: UniProtKB:Q9UFY1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021277 ! DKFZp434N101_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059119 name: Q9UG07_HUMAN def: "Putative uncharacterized protein DKFZp586M1622" [UniProtKB:Q9UG07] synonym: "Dishevelled, dsh homolog 3 (Drosophila), isoform CRA_b" EXACT [UniProtKB:Q9UG07] xref: EMBL:CAB53713.1 xref: EMBL:EAW78294.1 xref: UniProtKB:Q9UG07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021278 ! DKFZp586M1622_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059120 name: O14J1_HUMAN def: "Olfactory receptor 14J1" [UniProtKB:Q9UGF5] synonym: "Hs6M1-28" EXACT [UniProtKB:Q9UGF5] synonym: "Olfactory receptor 5U1" EXACT [UniProtKB:Q9UGF5] synonym: "Olfactory receptor OR6-25" EXACT [UniProtKB:Q9UGF5] xref: EMBL:CAB65799.1 xref: EMBL:CAI17513.1 xref: EMBL:CAI18129.1 xref: EMBL:DAA04839.1 xref: UniProtKB:Q5ST27 xref: UniProtKB:Q9UGF5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018952 ! OR14J1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059121 name: OR5V1_HUMAN def: "Olfactory receptor 5V1" [UniProtKB:Q9UGF6] synonym: "Hs6M1-21" EXACT [UniProtKB:Q9UGF6] synonym: "Olfactory receptor OR6-26" EXACT [UniProtKB:Q9UGF6] xref: EMBL:CAB65797.1 xref: EMBL:CAD31042.1 xref: EMBL:CAI17829.1 xref: EMBL:CAI18131.1 xref: EMBL:DAA04838.1 xref: UniProtKB:Q5SQI9 xref: UniProtKB:Q8IVL3 xref: UniProtKB:Q9UGF6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019194 ! OR5V1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059122 name: O12D3_HUMAN def: "Olfactory receptor 12D3" [UniProtKB:Q9UGF7] synonym: "Hs6M1-27" EXACT [UniProtKB:Q9UGF7] synonym: "Olfactory receptor OR6-27" EXACT [UniProtKB:Q9UGF7] xref: EMBL:AAH69082.1 xref: EMBL:AAH69154.1 xref: EMBL:AAI03893.1 xref: EMBL:CAB65796.1 xref: EMBL:CAD31041.1 xref: EMBL:CAI17830.1 xref: EMBL:CAI18132.1 xref: EMBL:CAM25848.1 xref: EMBL:DAA04837.1 xref: UniProtKB:A2BDZ1 xref: UniProtKB:Q5SQI8 xref: UniProtKB:Q6IF23 xref: UniProtKB:Q9UGF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018939 ! OR12D3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059123 name: SRGEF_HUMAN def: "Secretion-regulating guanine nucleotide exchange factor" [UniProtKB:Q9UGK8] synonym: "Deafness locus-associated putative guanine nucleotide exchange factor" EXACT [UniProtKB:Q9UGK8] synonym: "DelGEF" EXACT [UniProtKB:Q9UGK8] synonym: "Guanine nucleotide exchange factor-related protein" EXACT [UniProtKB:Q9UGK8] xref: EMBL:AAH65375.1 xref: EMBL:CAB60832.1 xref: EMBL:CAB60833.1 xref: UniProtKB:Q9UGK8 xref: UniProtKB:Q9UGK9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020036 ! SERGEF_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017352 ! zcsl2-gnefr-1 physical interaction relationship: participates_in CCO:I0017353 ! zcsl2-gnefr-3 physical interaction relationship: participates_in CCO:I0018299 ! zcsl2-gnefr-2 physical interaction relationship: participates_in CCO:I0018776 ! sec5-gnefr-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070912 ! SRGEF_HUMAN-Phosphoserine427 [Term] id: CCO:B0059124 name: JAD1B_HUMAN def: "Histone demethylase JARID1B" [UniProtKB:Q9UGL1] synonym: "Cancer/testis antigen 31" EXACT [UniProtKB:Q9UGL1] synonym: "CT31" EXACT [UniProtKB:Q9UGL1] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q9UGL1] synonym: "Jumonji/ARID domain-containing protein 1B" EXACT [UniProtKB:Q9UGL1] synonym: "PLU-1" EXACT [UniProtKB:Q9UGL1] synonym: "RBP2-H1" EXACT [UniProtKB:Q9UGL1] synonym: "Retinoblastoma-binding protein 2 homolog 1" EXACT [UniProtKB:Q9UGL1] xref: EMBL:AAD16061.1 xref: EMBL:CAB43532.1 xref: EMBL:CAB63108.1 xref: UniProtKB:O95811 xref: UniProtKB:Q15752 xref: UniProtKB:Q9UGL1 xref: UniProtKB:Q9Y3Q5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018353 ! JARID1B_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0067183 ! JAD1B_HUMAN-Phosphoserine1383 relationship: transforms_into CCO:B0067184 ! JAD1B_HUMAN-Phosphoserine1384 relationship: transforms_into CCO:B0067185 ! JAD1B_HUMAN-Phosphoserine1405 [Term] id: CCO:B0059125 name: DPOLL_HUMAN def: "DNA polymerase lambda" [UniProtKB:Q9UGP5] synonym: "DNA polymerase beta-2" EXACT [UniProtKB:Q9UGP5] synonym: "DNA polymerase kappa" EXACT [UniProtKB:Q9UGP5] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9UGP5] synonym: "EC 4.2.99.-" EXACT [UniProtKB:Q9UGP5] synonym: "Pol beta2" EXACT [UniProtKB:Q9UGP5] synonym: "Pol Lambda" EXACT [UniProtKB:Q9UGP5] xref: EMBL:AAF27541.1 xref: EMBL:AAG22519.1 xref: EMBL:AAH68529.1 xref: EMBL:AAM77696.1 xref: EMBL:BAB14050.1 xref: EMBL:CAB65074.1 xref: EMBL:CAI41032.1 xref: UniProtKB:Q5JQP5 xref: UniProtKB:Q6NUM2 xref: UniProtKB:Q9HA10 xref: UniProtKB:Q9HB35 xref: UniProtKB:Q9UGP5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017609 ! POLL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000628 ! DNA replication relationship: transforms_into CCO:B0064856 ! DPOLL_HUMAN-Phosphoserine246 [Term] id: CCO:B0059126 name: TCF20_HUMAN def: "Transcription factor 20" [UniProtKB:Q9UGU0] synonym: "AR1" EXACT [UniProtKB:Q9UGU0] synonym: "Nuclear factor SPBP" EXACT [UniProtKB:Q9UGU0] synonym: "SPRE-binding protein" EXACT [UniProtKB:Q9UGU0] synonym: "Stromelysin 1 PDGF-responsive element-binding protein" EXACT [UniProtKB:Q9UGU0] xref: EMBL:AAC36392.1 xref: EMBL:AAG28930.1 xref: EMBL:BAA22961.1 xref: EMBL:CAB42440.1 xref: EMBL:CAI95721.1 xref: UniProtKB:O14528 xref: UniProtKB:Q13078 xref: UniProtKB:Q4V353 xref: UniProtKB:Q9H4M0 xref: UniProtKB:Q9UGU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020213 ! TCF20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071265 ! TCF20_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0071266 ! TCF20_HUMAN-Phosphoserine419 relationship: transforms_into CCO:B0071267 ! TCF20_HUMAN-Phosphoserine430 relationship: transforms_into CCO:B0071268 ! TCF20_HUMAN-Phosphoserine505 relationship: transforms_into CCO:B0071269 ! TCF20_HUMAN-Phosphoserine538 relationship: transforms_into CCO:B0071270 ! TCF20_HUMAN-Phosphotyrosine548 relationship: transforms_into CCO:B0071271 ! TCF20_HUMAN-Phosphoserine559 relationship: transforms_into CCO:B0071272 ! TCF20_HUMAN-Phosphoserine574 relationship: transforms_into CCO:B0071273 ! TCF20_HUMAN-Phosphoserine583 relationship: transforms_into CCO:B0071274 ! TCF20_HUMAN-Phosphoserine627 relationship: transforms_into CCO:B0071275 ! TCF20_HUMAN-Phosphoserine640 relationship: transforms_into CCO:B0071276 ! TCF20_HUMAN-Phosphoserine871 relationship: transforms_into CCO:B0071277 ! TCF20_HUMAN-Phosphoserine1005 relationship: transforms_into CCO:B0071278 ! TCF20_HUMAN-Phosphoserine1122 relationship: transforms_into CCO:B0071279 ! TCF20_HUMAN-Phosphoserine1335 relationship: transforms_into CCO:B0071280 ! TCF20_HUMAN-Phosphoserine1361 relationship: transforms_into CCO:B0071281 ! TCF20_HUMAN-Phosphoserine1522 relationship: transforms_into CCO:B0071282 ! TCF20_HUMAN-Phosphoserine1669 relationship: transforms_into CCO:B0071283 ! TCF20_HUMAN-Phosphothreonine1671 [Term] id: CCO:B0059127 name: HM2L1_HUMAN def: "High mobility group protein 2-like 1" [UniProtKB:Q9UGU5] synonym: "Protein HMGBCG" EXACT [UniProtKB:Q9UGU5] xref: EMBL:CAA08991.1 xref: EMBL:CAA08992.1 xref: EMBL:CAB45240.1 xref: EMBL:CAG30390.1 xref: EMBL:CAI21632.1 xref: UniProtKB:O75672 xref: UniProtKB:O75673 xref: UniProtKB:Q9UGU5 xref: UniProtKB:Q9UMT5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018138 ! HMG2L1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059128 name: NDRG3_HUMAN def: "Protein NDRG3" [UniProtKB:Q9UGV2] xref: EMBL:AAK34944.1 xref: EMBL:AAL08807.1 xref: EMBL:BAB14620.1 xref: EMBL:BAB20067.1 xref: EMBL:BAB55277.1 xref: EMBL:CAI21399.1 xref: EMBL:CAI21461.1 xref: UniProtKB:Q5TH32 xref: UniProtKB:Q96PL8 xref: UniProtKB:Q96SM2 xref: UniProtKB:Q9BXY7 xref: UniProtKB:Q9H3N7 xref: UniProtKB:Q9H411 xref: UniProtKB:Q9H8J6 xref: UniProtKB:Q9UGV2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018741 ! NDRG3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: transforms_into CCO:B0068540 ! NDRG3_HUMAN-Phosphothreonine322 relationship: transforms_into CCO:B0068541 ! NDRG3_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0068542 ! NDRG3_HUMAN-Phosphothreonine332 relationship: transforms_into CCO:B0068543 ! NDRG3_HUMAN-Phosphoserine334 relationship: transforms_into CCO:B0068544 ! NDRG3_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0068545 ! NDRG3_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0068546 ! NDRG3_HUMAN-Phosphoserine374 [Term] id: CCO:B0059129 name: Q9UH66_HUMAN def: "7h3 protein" [UniProtKB:Q9UH66] xref: EMBL:AAF22843.1 xref: UniProtKB:Q9UH66 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059130 name: MLX_HUMAN def: "Max-like protein X" [UniProtKB:Q9UH92] synonym: "BigMax protein" EXACT [UniProtKB:Q9UH92] synonym: "Max-like bHLHZip protein" EXACT [UniProtKB:Q9UH92] synonym: "Protein Mlx" EXACT [UniProtKB:Q9UH92] synonym: "Transcription factor-like protein 4" EXACT [UniProtKB:Q9UH92] xref: EMBL:AAF14638.1 xref: EMBL:AAG40145.1 xref: EMBL:AAG40146.1 xref: EMBL:AAG40147.1 xref: EMBL:AAH10689.1 xref: EMBL:AAP88814.1 xref: EMBL:BAA90977.1 xref: UniProtKB:Q53XM6 xref: UniProtKB:Q96FL2 xref: UniProtKB:Q9H2V0 xref: UniProtKB:Q9H2V1 xref: UniProtKB:Q9H2V2 xref: UniProtKB:Q9NXN3 xref: UniProtKB:Q9UH92 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018638 ! MLX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014995 ! gabarapl2-mlx physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068241 ! MLX_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0068242 ! MLX_HUMAN-Phosphoserine48 [Term] id: CCO:B0059131 name: MK1I1_HUMAN def: "Mitogen-activated protein kinase kinase 1-interacting protein 1" [UniProtKB:Q9UHA4] synonym: "MEK-binding partner 1" EXACT [UniProtKB:Q9UHA4] synonym: "Mp1" EXACT [UniProtKB:Q9UHA4] xref: EMBL:AAF17239.1 xref: EMBL:AAG35540.1 xref: EMBL:AAH26245.1 xref: UniProtKB:Q9H364 xref: UniProtKB:Q9UHA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018630 ! MAP2K1IP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004132 ! kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: participates_in CCO:P0000410 ! activation of MAPKK activity [Term] id: CCO:B0059132 name: LIMA1_HUMAN def: "LIM domain and actin-binding protein 1" [UniProtKB:Q9UHB6] synonym: "Epithelial protein lost in neoplasm" EXACT [UniProtKB:Q9UHB6] xref: EMBL:AAF23755.1 xref: EMBL:AAF23756.1 xref: EMBL:AAF67491.1 xref: EMBL:AAG17267.1 xref: EMBL:AAH01247.2 xref: EMBL:AAH10664.1 xref: EMBL:AAI10816.1 xref: EMBL:BAA90914.1 xref: EMBL:BAA91092.1 xref: EMBL:BAA91120.1 xref: EMBL:BAB14625.1 xref: EMBL:CAB66845.1 xref: UniProtKB:Q2TAN7 xref: UniProtKB:Q9BVF2 xref: UniProtKB:Q9H8J1 xref: UniProtKB:Q9HBN5 xref: UniProtKB:Q9NX96 xref: UniProtKB:Q9NXC3 xref: UniProtKB:Q9NXU6 xref: UniProtKB:Q9P0H8 xref: UniProtKB:Q9UHB5 xref: UniProtKB:Q9UHB6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018494 ! LIMA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0001328 ! negative regulation of actin filament depolymerization relationship: transforms_into CCO:B0067646 ! LIMA1_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0067647 ! LIMA1_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0067648 ! LIMA1_HUMAN-Phosphoserine225 relationship: transforms_into CCO:B0067649 ! LIMA1_HUMAN-Phosphotyrosine229 relationship: transforms_into CCO:B0067650 ! LIMA1_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0067651 ! LIMA1_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0067652 ! LIMA1_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0067653 ! LIMA1_HUMAN-Phosphoserine369 relationship: transforms_into CCO:B0067654 ! LIMA1_HUMAN-Phosphoserine374 relationship: transforms_into CCO:B0067655 ! LIMA1_HUMAN-Phosphothreonine487 relationship: transforms_into CCO:B0067656 ! LIMA1_HUMAN-Phosphoserine490 relationship: transforms_into CCO:B0067657 ! LIMA1_HUMAN-Phosphoserine541 relationship: transforms_into CCO:B0067658 ! LIMA1_HUMAN-Phosphoserine604 relationship: transforms_into CCO:B0067659 ! LIMA1_HUMAN-Phosphoserine609 relationship: transforms_into CCO:B0067660 ! LIMA1_HUMAN-Phosphoserine617 relationship: transforms_into CCO:B0067661 ! LIMA1_HUMAN-Phosphoserine619 relationship: transforms_into CCO:B0067662 ! LIMA1_HUMAN-Phosphoserine622 relationship: transforms_into CCO:B0067663 ! LIMA1_HUMAN-Phosphoserine686 relationship: transforms_into CCO:B0067664 ! LIMA1_HUMAN-Phosphoserine692 relationship: transforms_into CCO:B0067665 ! LIMA1_HUMAN-Phosphoserine698 relationship: transforms_into CCO:B0067666 ! LIMA1_HUMAN-Phosphotyrosine752 [Term] id: CCO:B0059133 name: AFF4_HUMAN def: "AF4/FMR2 family member 4" [UniProtKB:Q9UHB7] synonym: "ALL1-fused gene from chromosome 5q31" EXACT [UniProtKB:Q9UHB7] synonym: "Major CDK9 elongation factor-associated protein" EXACT [UniProtKB:Q9UHB7] xref: EMBL:AAF18981.1 xref: EMBL:AAF28915.1 xref: EMBL:AAH63007.1 xref: EMBL:AAI00288.1 xref: EMBL:AAM00184.2 xref: EMBL:BAD92784.1 xref: UniProtKB:Q498B2 xref: UniProtKB:Q59FB3 xref: UniProtKB:Q6P592 xref: UniProtKB:Q8TDR1 xref: UniProtKB:Q9P0E4 xref: UniProtKB:Q9UHB7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006029 ! AFF4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0065473 ! AFF4_HUMAN-Phosphoserine387 relationship: transforms_into CCO:B0065474 ! AFF4_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0065475 ! AFF4_HUMAN-Phosphoserine389 relationship: transforms_into CCO:B0065476 ! AFF4_HUMAN-Phosphoserine392 relationship: transforms_into CCO:B0065477 ! AFF4_HUMAN-Phosphoserine499 relationship: transforms_into CCO:B0065478 ! AFF4_HUMAN-Phosphoserine549 relationship: transforms_into CCO:B0065479 ! AFF4_HUMAN-Phosphothreonine674 relationship: transforms_into CCO:B0065480 ! AFF4_HUMAN-Phosphoserine694 relationship: transforms_into CCO:B0065481 ! AFF4_HUMAN-Phosphoserine703 relationship: transforms_into CCO:B0065482 ! AFF4_HUMAN-Phosphoserine706 relationship: transforms_into CCO:B0065483 ! AFF4_HUMAN-Phosphotyrosine712 relationship: transforms_into CCO:B0065484 ! AFF4_HUMAN-Phosphoserine1043 relationship: transforms_into CCO:B0065485 ! AFF4_HUMAN-Phosphoserine1055 relationship: transforms_into CCO:B0065486 ! AFF4_HUMAN-Phosphoserine1058 relationship: transforms_into CCO:B0065487 ! AFF4_HUMAN-Phosphoserine1062 [Term] id: CCO:B0059134 name: ACCN3_HUMAN def: "Amiloride-sensitive cation channel 3" [UniProtKB:Q9UHC3] synonym: "Acid-sensing ion channel 3" EXACT [UniProtKB:Q9UHC3] synonym: "ASIC3" EXACT [UniProtKB:Q9UHC3] synonym: "hASIC3" EXACT [UniProtKB:Q9UHC3] synonym: "hTNaC1" EXACT [UniProtKB:Q9UHC3] synonym: "Neuronal amiloride-sensitive cation channel 3" EXACT [UniProtKB:Q9UHC3] synonym: "Testis sodium channel 1" EXACT [UniProtKB:Q9UHC3] xref: EMBL:AAC62935.1 xref: EMBL:AAC64188.1 xref: EMBL:AAF19817.1 xref: EMBL:AAF19818.1 xref: EMBL:BAA25897.1 xref: EMBL:BAD92658.1 xref: UniProtKB:O60263 xref: UniProtKB:O75906 xref: UniProtKB:Q59FN9 xref: UniProtKB:Q9UER8 xref: UniProtKB:Q9UHC3 xref: UniProtKB:Q9UHC4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016882 ! ACCN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065313 ! ACCN3_HUMAN-Phosphotyrosine375 relationship: transforms_into CCO:B0065314 ! ACCN3_HUMAN-Phosphoserine521 [Term] id: CCO:B0059135 name: CNTP2_HUMAN def: "Contactin-associated protein-like 2 precursor" [UniProtKB:Q9UHC6] synonym: "Cell recognition molecule Caspr2" EXACT [UniProtKB:Q9UHC6] xref: EMBL:AAF25199.1 xref: EMBL:AAH93780.1 xref: EMBL:AAI13374.1 xref: EMBL:AAK34932.1 xref: EMBL:AAK49902.1 xref: EMBL:AAK49903.1 xref: EMBL:BAA74891.1 xref: EMBL:CAI45967.1 xref: UniProtKB:Q14DG2 xref: UniProtKB:Q52LV1 xref: UniProtKB:Q5H9Q7 xref: UniProtKB:Q9UHC6 xref: UniProtKB:Q9UQ12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017418 ! CNTNAP2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017287 ! cntnap2-kiaa1224 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059136 name: IL19_HUMAN def: "Interleukin-19 precursor" [UniProtKB:Q9UHD0] synonym: "IL-19" EXACT [UniProtKB:Q9UHD0] synonym: "Melanoma differentiation-associated protein-like protein" EXACT [UniProtKB:Q9UHD0] synonym: "NG.1" EXACT [UniProtKB:Q9UHD0] xref: EMBL:AAF06663.1 xref: EMBL:AAG16755.1 xref: EMBL:AAK64498.1 xref: EMBL:AAK91776.1 xref: EMBL:AAN40906.1 xref: EMBL:CAB72342.1 xref: UniProtKB:Q96QR4 xref: UniProtKB:Q9NUA0 xref: UniProtKB:Q9UHD0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018254 ! IL19_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059137 name: CIDEB_HUMAN def: "Cell death activator CIDE-B" [UniProtKB:Q9UHD4] synonym: "Cell death-inducing DFFA-like effector B" EXACT [UniProtKB:Q9UHD4] xref: EMBL:AAF23324.1 xref: EMBL:AAF27658.1 xref: EMBL:AAH35970.1 xref: EMBL:BAA91132.1 xref: UniProtKB:Q9NNW9 xref: UniProtKB:Q9UHD4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017363 ! CIDEB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis relationship: transforms_into CCO:B0064355 ! CIDEB_HUMAN-Phosphoserine17 [Term] id: CCO:B0059138 name: TRPS1_HUMAN def: "Zinc finger transcription factor Trps1" [UniProtKB:Q9UHF7] synonym: "Tricho-rhino-phalangeal syndrome type I protein" EXACT [UniProtKB:Q9UHF7] synonym: "Zinc finger protein GC79" EXACT [UniProtKB:Q9UHF7] xref: EMBL:AAF23614.1 xref: EMBL:AAG21134.1 xref: EMBL:BAA91441.1 xref: UniProtKB:Q9NWE1 xref: UniProtKB:Q9UHF7 xref: UniProtKB:Q9UHH6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020363 ! TRPS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071586 ! TRPS1_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0071587 ! TRPS1_HUMAN-Phosphoserine892 relationship: transforms_into CCO:B0071588 ! TRPS1_HUMAN-Phosphoserine1081 relationship: transforms_into CCO:B0071589 ! TRPS1_HUMAN-Phosphoserine1085 [Term] id: CCO:B0059139 name: PCSK1_HUMAN def: "ProSAAS precursor" [UniProtKB:Q9UHG2] synonym: "pro-SAAS" EXACT [UniProtKB:Q9UHG2] synonym: "Proprotein convertase 1 inhibitor" EXACT [UniProtKB:Q9UHG2] synonym: "Proprotein convertase subtilisin/kexin type 1 inhibitor" EXACT [UniProtKB:Q9UHG2] xref: EMBL:AAF22643.1 xref: EMBL:AAH02851.1 xref: UniProtKB:Q4VC04 xref: UniProtKB:Q9UHG2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019323 ! PCSK1N_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000985 ! secretory granule relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0059140 name: IP6K2_HUMAN def: "Inositol hexakisphosphate kinase 2" [UniProtKB:Q9UHH9] synonym: "EC 2.7.4.21" EXACT [UniProtKB:Q9UHH9] synonym: "InsP6 kinase 2" EXACT [UniProtKB:Q9UHH9] synonym: "P(i)-uptake stimulator" EXACT [UniProtKB:Q9UHH9] synonym: "PiUS" EXACT [UniProtKB:Q9UHH9] xref: EMBL:AAF15057.1 xref: EMBL:AAG01984.1 xref: EMBL:AAH01864.1 xref: EMBL:AAH04469.2 xref: EMBL:AAH19694.1 xref: EMBL:AAH65533.1 xref: EMBL:CAB55936.1 xref: EMBL:CAB70780.1 xref: UniProtKB:Q6P0N8 xref: UniProtKB:Q9BSZ6 xref: UniProtKB:Q9BUW3 xref: UniProtKB:Q9H4P7 xref: UniProtKB:Q9NT63 xref: UniProtKB:Q9UFU6 xref: UniProtKB:Q9UHH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018299 ! IHPK2_human relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0001903 ! inositol trisphosphate 3-kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015343 ! ihpk2-plscr1 physical interaction relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:B0059141 name: DDX20_HUMAN def: "Probable ATP-dependent RNA helicase DDX20" [UniProtKB:Q9UHI6] synonym: "Component of gems 3" EXACT [UniProtKB:Q9UHI6] synonym: "DEAD box protein 20" EXACT [UniProtKB:Q9UHI6] synonym: "DEAD box protein DP 103" EXACT [UniProtKB:Q9UHI6] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9UHI6] synonym: "Gemin-3" EXACT [UniProtKB:Q9UHI6] xref: EMBL:AAD42744.1 xref: EMBL:AAF14544.1 xref: EMBL:AAH11556.1 xref: EMBL:BAA91727.1 xref: EMBL:CAB55686.2 xref: EMBL:CAB63734.2 xref: UniProtKB:Q96F72 xref: UniProtKB:Q9NVM3 xref: UniProtKB:Q9UF59 xref: UniProtKB:Q9UHI6 xref: UniProtKB:Q9UIY0 xref: UniProtKB:Q9Y659 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017546 ! DDX20_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0017671 ! gemin5-ddx20-1 physical interaction relationship: participates_in CCO:I0018463 ! bat2-ddx20 physical interaction relationship: participates_in CCO:I0018600 ! gemin5-gemin4-1 physical interaction relationship: participates_in CCO:I0018601 ! gemin5-smn1-1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0064695 ! DDX20_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0064696 ! DDX20_HUMAN-Phosphoserine500 relationship: transforms_into CCO:B0064697 ! DDX20_HUMAN-Phosphoserine532 relationship: transforms_into CCO:B0064698 ! DDX20_HUMAN-Phosphothreonine552 relationship: transforms_into CCO:B0064699 ! DDX20_HUMAN-Phosphoserine649 relationship: transforms_into CCO:B0064700 ! DDX20_HUMAN-Phosphoserine652 relationship: transforms_into CCO:B0064701 ! DDX20_HUMAN-Phosphoserine654 relationship: transforms_into CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: transforms_into CCO:B0064703 ! DDX20_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0064704 ! DDX20_HUMAN-Phosphoserine677 relationship: transforms_into CCO:B0064705 ! DDX20_HUMAN-Phosphoserine678 relationship: transforms_into CCO:B0064706 ! DDX20_HUMAN-Phosphoserine703 relationship: transforms_into CCO:B0064707 ! DDX20_HUMAN-Phosphothreonine705 relationship: transforms_into CCO:B0064708 ! DDX20_HUMAN-Phosphoserine714 [Term] id: CCO:B0059142 name: SMBT1_HUMAN def: "Scm-like with four MBT domains protein 1" [UniProtKB:Q9UHJ3] synonym: "Renal ubiquitous protein 1" EXACT [UniProtKB:Q9UHJ3] xref: EMBL:AAF19794.1 xref: EMBL:AAH14614.1 xref: EMBL:CAB45734.1 xref: UniProtKB:Q96C73 xref: UniProtKB:Q9UHJ3 xref: UniProtKB:Q9Y4Q9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019946 ! SFMBT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015336 ! phc1-sfmbt1 physical interaction relationship: participates_in CCO:I0015778 ! acp1-sfmbt1 physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070614 ! SMBT1_HUMAN-Phosphoserine765 relationship: transforms_into CCO:B0070615 ! SMBT1_HUMAN-Phosphoserine767 relationship: transforms_into CCO:B0070616 ! SMBT1_HUMAN-Phosphoserine775 [Term] id: CCO:B0059143 name: NUFP1_HUMAN def: "Nuclear fragile X mental retardation-interacting protein 1" [UniProtKB:Q9UHK0] synonym: "Nuclear FMRP-interacting protein 1" EXACT [UniProtKB:Q9UHK0] xref: EMBL:AAF15315.1 xref: EMBL:AAH17745.1 xref: EMBL:CAC40689.2 xref: EMBL:CAI12865.1 xref: UniProtKB:Q8WVM5 xref: UniProtKB:Q96SG1 xref: UniProtKB:Q9UHK0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018888 ! NUFIP1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000316 ! perichromatin fibrils relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0002007 ! presynaptic active zone relationship: located_in CCO:C0002088 ! cytosolic ribosome relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068910 ! NUFP1_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0068911 ! NUFP1_HUMAN-Phosphoserine338 relationship: transforms_into CCO:B0068912 ! NUFP1_HUMAN-Phosphoserine340 relationship: transforms_into CCO:B0068913 ! NUFP1_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0068914 ! NUFP1_HUMAN-Phosphotyrosine476 relationship: transforms_into CCO:B0068915 ! NUFP1_HUMAN-Phosphothreonine487 relationship: transforms_into CCO:B0068916 ! NUFP1_HUMAN-Phosphoserine489 [Term] id: CCO:B0059144 name: DDX25_HUMAN def: "ATP-dependent RNA helicase DDX25" [UniProtKB:Q9UHL0] synonym: "DEAD box protein 25" EXACT [UniProtKB:Q9UHL0] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9UHL0] synonym: "Gonadotropin-regulated testicular RNA helicase" EXACT [UniProtKB:Q9UHL0] xref: EMBL:AAF21371.2 xref: EMBL:AAH35388.2 xref: EMBL:AAH50360.2 xref: EMBL:AAU84667.1 xref: UniProtKB:Q5XVN2 xref: UniProtKB:Q86W81 xref: UniProtKB:Q8IYP1 xref: UniProtKB:Q9UHL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017547 ! DDX25_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001574 ! chromatoid body relationship: participates_in CCO:P0000660 ! regulation of translation [Term] id: CCO:B0059145 name: DPOG2_HUMAN def: "DNA polymerase subunit gamma-2, mitochondrial precursor" [UniProtKB:Q9UHN1] synonym: "DNA polymerase gamma accessory 55 kDa subunit" EXACT [UniProtKB:Q9UHN1] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9UHN1] synonym: "Mitochondrial DNA polymerase accessory subunit" EXACT [UniProtKB:Q9UHN1] synonym: "MtPolB" EXACT [UniProtKB:Q9UHN1] synonym: "p55" EXACT [UniProtKB:Q9UHN1] synonym: "PolG-beta" EXACT [UniProtKB:Q9UHN1] xref: EMBL:AAC51321.1 xref: EMBL:AAD50382.1 xref: EMBL:AAD56542.1 xref: EMBL:AAD56640.1 xref: EMBL:AAH00913.2 xref: EMBL:AAH09194.1 xref: UniProtKB:O00419 xref: UniProtKB:Q0IJ81 xref: UniProtKB:Q96GW2 xref: UniProtKB:Q9UHN1 xref: UniProtKB:Q9UK35 xref: UniProtKB:Q9UK94 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017607 ! POLG2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001178 ! glycine-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000045 ! mitochondrial chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0018214 ! polg-polg2-3 physical interaction relationship: participates_in CCO:I0018215 ! polg-polg2-4 physical interaction relationship: participates_in CCO:I0018864 ! polg-polg2-1 direct interaction relationship: participates_in CCO:I0019289 ! polg-polg2-2 physical interaction relationship: participates_in CCO:I0019442 ! polg-polg2-5 physical interaction relationship: participates_in CCO:I0019443 ! polg-polg2-6 physical interaction relationship: participates_in CCO:I0019444 ! dpol-gamma_human physical interaction relationship: participates_in CCO:P0000628 ! DNA replication relationship: participates_in CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:B0059146 name: CLC2D_HUMAN def: "C-type lectin domain family 2 member D" [UniProtKB:Q9UHP7] synonym: "Lectin-like NK cell receptor" EXACT [UniProtKB:Q9UHP7] synonym: "Lectin-like transcript 1" EXACT [UniProtKB:Q9UHP7] synonym: "LLT-1" EXACT [UniProtKB:Q9UHP7] synonym: "Osteoclast inhibitory lectin" EXACT [UniProtKB:Q9UHP7] xref: EMBL:AAF22159.1 xref: EMBL:AAG00514.1 xref: EMBL:AAG00515.1 xref: EMBL:AAG00516.1 xref: EMBL:AAH19883.1 xref: EMBL:AAN59996.1 xref: EMBL:EAW96114.1 xref: UniProtKB:Q6YID5 xref: UniProtKB:Q8WUP7 xref: UniProtKB:Q9HD37 xref: UniProtKB:Q9HD38 xref: UniProtKB:Q9UHP7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017377 ! CLEC2D_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0059147 name: BI2L1_HUMAN def: "Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1" [UniProtKB:Q9UHR4] synonym: "BAI1-associated protein 2-like protein 1" EXACT [UniProtKB:Q9UHR4] synonym: "Insulin receptor tyrosine kinase substrate" EXACT [UniProtKB:Q9UHR4] xref: EMBL:AAD20937.1 xref: EMBL:AAF17223.2 xref: EMBL:AAH13888.1 xref: EMBL:AAS07549.1 xref: EMBL:AAS07550.1 xref: EMBL:BAB15671.1 xref: EMBL:EAL23890.1 xref: EMBL:EAW76706.1 xref: UniProtKB:A4D268 xref: UniProtKB:Q75L21 xref: UniProtKB:Q75L22 xref: UniProtKB:Q96CV4 xref: UniProtKB:Q9H5F5 xref: UniProtKB:Q9UHR4 xref: UniProtKB:Q9Y2M8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017152 ! BAIAP2L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0063903 ! BI2L1_HUMAN-Phosphothreonine248 relationship: transforms_into CCO:B0063904 ! BI2L1_HUMAN-Phosphothreonine257 relationship: transforms_into CCO:B0063905 ! BI2L1_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0063906 ! BI2L1_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0063907 ! BI2L1_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0063908 ! BI2L1_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0063909 ! BI2L1_HUMAN-Phosphothreonine412 relationship: transforms_into CCO:B0063910 ! BI2L1_HUMAN-Phosphoserine414 [Term] id: CCO:B0059148 name: S30BP_HUMAN def: "SAP30-binding protein" [UniProtKB:Q9UHR5] synonym: "Transcriptional regulator protein HCNGP" EXACT [UniProtKB:Q9UHR5] xref: EMBL:AAF17221.1 xref: EMBL:AAH07592.1 xref: EMBL:AAH13409.2 xref: EMBL:AAH30233.1 xref: EMBL:AAH63793.1 xref: EMBL:AAL47177.1 xref: EMBL:AAL92491.1 xref: EMBL:AAM10497.1 xref: EMBL:BAC04514.1 xref: UniProtKB:Q8N1R5 xref: UniProtKB:Q8TDR8 xref: UniProtKB:Q96D27 xref: UniProtKB:Q9UHR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019824 ! SAP30BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: transforms_into CCO:B0070279 ! S30BP_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0070280 ! S30BP_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0070281 ! S30BP_HUMAN-Phosphoserine43 relationship: transforms_into CCO:B0070282 ! S30BP_HUMAN-Phosphoserine113 [Term] id: CCO:B0059149 name: Q9UHV4_HUMAN def: "PDZ domain-containing guanine nucleotide exchange factor I" [UniProtKB:Q9UHV4] xref: EMBL:AAF22004.1 xref: UniProtKB:Q9UHV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0059150 name: RPGFL_HUMAN def: "Rap guanine nucleotide exchange factor-like 1" [UniProtKB:Q9UHV5] synonym: "Link GEFII" EXACT [UniProtKB:Q9UHV5] synonym: "Link guanine nucleotide exchange factor II" EXACT [UniProtKB:Q9UHV5] xref: EMBL:AAF22003.1 xref: EMBL:AAI15375.1 xref: EMBL:AAI15376.1 xref: EMBL:BAG36274.1 xref: UniProtKB:Q9UHV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022605 ! RAPGEFL1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0059151 name: PUF60_HUMAN def: "Poly(U)-binding-splicing factor PUF60" [UniProtKB:Q9UHX1] synonym: "60 kDa poly(U)-binding-splicing factor" EXACT [UniProtKB:Q9UHX1] synonym: "FBP-interacting repressor" EXACT [UniProtKB:Q9UHX1] synonym: "FUSE-binding protein-interacting repressor" EXACT [UniProtKB:Q9UHX1] synonym: "Ro-binding protein 1" EXACT [UniProtKB:Q9UHX1] synonym: "RoBP1" EXACT [UniProtKB:Q9UHX1] synonym: "Siah-binding protein 1" EXACT [UniProtKB:Q9UHX1] synonym: "Siah-BP1" EXACT [UniProtKB:Q9UHX1] xref: EMBL:AAB41656.1 xref: EMBL:AAF05605.1 xref: EMBL:AAF23589.1 xref: EMBL:AAF27522.2 xref: EMBL:AAH08875.1 xref: EMBL:AAH09734.1 xref: EMBL:AAH11265.1 xref: EMBL:AAH11979.1 xref: EMBL:CAG33424.1 xref: EMBL:EAW82189.1 xref: UniProtKB:Q969E7 xref: UniProtKB:Q96D94 xref: UniProtKB:Q96H63 xref: UniProtKB:Q99628 xref: UniProtKB:Q9NZA0 xref: UniProtKB:Q9UHX1 xref: UniProtKB:Q9UJY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019557 ! PUF60_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069621 ! PUF60_HUMAN-Phosphothreonine60 relationship: transforms_into CCO:B0069622 ! PUF60_HUMAN-Phosphoserine206 [Term] id: CCO:B0059152 name: EMR2_HUMAN def: "EGF-like module-containing mucin-like hormone receptor-like 2 precursor" [UniProtKB:Q9UHX3] synonym: "CD312 antigen" EXACT [UniProtKB:Q9UHX3] synonym: "EGF-like module EMR2" EXACT [UniProtKB:Q9UHX3] xref: EMBL:AAC05172.1 xref: EMBL:AAF21974.1 xref: EMBL:BAC06146.1 xref: UniProtKB:Q8NG96 xref: UniProtKB:Q9UHX3 xref: UniProtKB:Q9Y4B1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017705 ! EMR2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0059153 name: EVL_HUMAN def: "Ena/VASP-like protein" [UniProtKB:Q9UI08] synonym: "Ena/vasodilator-stimulated phosphoprotein-like" EXACT [UniProtKB:Q9UI08] xref: EMBL:AAD20040.1 xref: EMBL:AAF17197.1 xref: EMBL:AAF21709.1 xref: EMBL:AAH23997.1 xref: EMBL:AAH32358.1 xref: EMBL:AAP97156.1 xref: EMBL:CAB63763.2 xref: UniProtKB:O95884 xref: UniProtKB:Q7Z522 xref: UniProtKB:Q8TBV1 xref: UniProtKB:Q9UF25 xref: UniProtKB:Q9UI08 xref: UniProtKB:Q9UIC2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017743 ! EVL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018430 ! hck-evl-1 physical interaction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0065172 ! EVL_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0065173 ! EVL_HUMAN-Phosphothreonine250 relationship: transforms_into CCO:B0065174 ! EVL_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0065175 ! EVL_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0065176 ! EVL_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0065177 ! EVL_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0065178 ! EVL_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0065179 ! EVL_HUMAN-Phosphoserine349 [Term] id: CCO:B0059154 name: EI2BD_HUMAN def: "Translation initiation factor eIF-2B subunit delta" [UniProtKB:Q9UI10] synonym: "eIF-2B GDP-GTP exchange factor subunit delta" EXACT [UniProtKB:Q9UI10] xref: EMBL:AAF17195.1 xref: EMBL:AAH01870.1 xref: EMBL:AAH91502.1 xref: EMBL:CAB57260.1 xref: EMBL:CAB57261.1 xref: EMBL:CAB57304.1 xref: EMBL:CAB57305.1 xref: UniProtKB:Q5BJF4 xref: UniProtKB:Q9BUV9 xref: UniProtKB:Q9UBG4 xref: UniProtKB:Q9UI10 xref: UniProtKB:Q9UIQ9 xref: UniProtKB:Q9UJ95 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017671 ! EIF2B4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000660 ! regulation of translation relationship: transforms_into CCO:B0064937 ! EI2BD_HUMAN-Phosphothreonine86 [Term] id: CCO:B0059155 name: CYH4_HUMAN def: "Cytohesin-4" [UniProtKB:Q9UIA0] synonym: "PH, SEC7 and coiled-coil domain-containing protein 4" EXACT [UniProtKB:Q9UIA0] xref: EMBL:AAF15389.1 xref: EMBL:AAF28896.1 xref: EMBL:AAH41161.1 xref: EMBL:CAG30437.1 xref: EMBL:CAI22121.1 xref: UniProtKB:Q5R3F9 xref: UniProtKB:Q9UGT6 xref: UniProtKB:Q9UIA0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017512 ! CYTH4_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0064610 ! CYH4_HUMAN-Phosphoserine356 [Term] id: CCO:B0059156 name: ZN639_HUMAN def: "Zinc finger protein 639" [UniProtKB:Q9UID6] synonym: "Zinc finger protein ANC_2H01" EXACT [UniProtKB:Q9UID6] synonym: "Zinc finger protein ZASC1" EXACT [UniProtKB:Q9UID6] xref: EMBL:AAF21240.1 xref: EMBL:AAH20500.1 xref: EMBL:AAH26181.1 xref: EMBL:BAC77610.1 xref: UniProtKB:Q9UID6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020868 ! ZNF639_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018915 ! aptx-znf639 physical interaction relationship: participates_in CCO:I0018918 ! aptx-znf639-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072201 ! ZN639_HUMAN-Phosphotyrosine4 [Term] id: CCO:B0059157 name: Q9UID7_HUMAN def: "CYR61 protein" [UniProtKB:Q9UID7] xref: EMBL:AAF21597.1 xref: UniProtKB:Q9UID7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017513 ! CYR61_human relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0059158 name: ZN230_HUMAN def: "Zinc finger protein 230" [UniProtKB:Q9UIE0] synonym: "Zinc finger protein FDZF2" EXACT [UniProtKB:Q9UIE0] xref: EMBL:AAB62180.1 xref: EMBL:AAF18685.1 xref: EMBL:AAF66074.1 xref: EMBL:AAH50340.2 xref: EMBL:AAH94708.1 xref: UniProtKB:O15322 xref: UniProtKB:Q504X7 xref: UniProtKB:Q86W84 xref: UniProtKB:Q9P1U6 xref: UniProtKB:Q9UIE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020669 ! ZNF230_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017483 ! mitap1-znf230 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059159 name: BAZ2B_HUMAN def: "Bromodomain adjacent to zinc finger domain protein 2B" [UniProtKB:Q9UIF8] synonym: "hWALp4" EXACT [UniProtKB:Q9UIF8] xref: EMBL:AAH12576.1 xref: EMBL:BAA89212.1 xref: EMBL:BAA96000.2 xref: EMBL:BAB55231.1 xref: EMBL:CAB45759.1 xref: EMBL:CAD39044.2 xref: UniProtKB:Q96EA1 xref: UniProtKB:Q96SQ8 xref: UniProtKB:Q9P252 xref: UniProtKB:Q9UIF8 xref: UniProtKB:Q9Y4N8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017134 ! BAZ2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015007 ! baz2b-ctbp2 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063780 ! BAZ2B_HUMAN-Phosphothreonine1087 [Term] id: CCO:B0059160 name: BAZ2A_HUMAN def: "Bromodomain adjacent to zinc finger domain protein 2A" [UniProtKB:Q9UIF9] synonym: "hWALp3" EXACT [UniProtKB:Q9UIF9] synonym: "Tip5" EXACT [UniProtKB:Q9UIF9] synonym: "Transcription termination factor I-interacting protein 5" EXACT [UniProtKB:Q9UIF9] synonym: "TTF-I-interacting protein 5" EXACT [UniProtKB:Q9UIF9] xref: EMBL:AAB60864.1 xref: EMBL:AAH08965.2 xref: EMBL:BAA20773.2 xref: EMBL:BAA89211.1 xref: UniProtKB:O00536 xref: UniProtKB:O15030 xref: UniProtKB:Q96H26 xref: UniProtKB:Q9UIF9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017133 ! BAZ2A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016322 ! smarca5-baz2a physical interaction relationship: participates_in CCO:I0018637 ! baz2a-fbl colocalization relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063771 ! BAZ2A_HUMAN-Phosphoserine469 relationship: transforms_into CCO:B0063772 ! BAZ2A_HUMAN-Phosphothreonine521 relationship: transforms_into CCO:B0063773 ! BAZ2A_HUMAN-Phosphoserine1024 relationship: transforms_into CCO:B0063774 ! BAZ2A_HUMAN-Phosphoserine1370 relationship: transforms_into CCO:B0063775 ! BAZ2A_HUMAN-Phosphoserine1532 relationship: transforms_into CCO:B0063776 ! BAZ2A_HUMAN-Phosphoserine1720 relationship: transforms_into CCO:B0063777 ! BAZ2A_HUMAN-Phosphoserine1743 relationship: transforms_into CCO:B0063778 ! BAZ2A_HUMAN-Phosphoserine1751 relationship: transforms_into CCO:B0063779 ! BAZ2A_HUMAN-Phosphoserine1756 [Term] id: CCO:B0059161 name: BAZ1B_HUMAN def: "Bromodomain adjacent to zinc finger domain protein 1B" [UniProtKB:Q9UIG0] synonym: "hWALP2" EXACT [UniProtKB:Q9UIG0] synonym: "Williams syndrome transcription factor" EXACT [UniProtKB:Q9UIG0] synonym: "Williams-Beuren syndrome chromosomal region 9 protein" EXACT [UniProtKB:Q9UIG0] xref: EMBL:AAC97879.1 xref: EMBL:AAD04720.1 xref: EMBL:AAD08675.1 xref: EMBL:BAA89210.1 xref: UniProtKB:O95039 xref: UniProtKB:O95247 xref: UniProtKB:O95277 xref: UniProtKB:Q9UIG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017132 ! BAZ1B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016152 ! baz1b-myo1c physical interaction relationship: participates_in CCO:I0016154 ! baz1b-smrca5 physical interaction relationship: participates_in CCO:I0016321 ! smarca5-myo1c physical interaction relationship: participates_in CCO:I0016322 ! smarca5-baz2a physical interaction relationship: participates_in CCO:I0017735 ! baz1b-myo1c-1 physical interaction relationship: participates_in CCO:I0018542 ! baz1a-baz1b-1 physical interaction relationship: participates_in CCO:I0018638 ! baz1b-polr1a colocalization relationship: participates_in CCO:I0019447 ! baz1b-smarca5 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0063753 ! BAZ1B_HUMAN-Phosphoserine161 relationship: transforms_into CCO:B0063754 ! BAZ1B_HUMAN-Phosphoserine167 relationship: transforms_into CCO:B0063755 ! BAZ1B_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0063756 ! BAZ1B_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0063757 ! BAZ1B_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0063758 ! BAZ1B_HUMAN-Phosphoserine347 relationship: transforms_into CCO:B0063759 ! BAZ1B_HUMAN-Phosphoserine349 relationship: transforms_into CCO:B0063760 ! BAZ1B_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0063761 ! BAZ1B_HUMAN-Phosphoserine374 relationship: transforms_into CCO:B0063762 ! BAZ1B_HUMAN-Phosphoserine699 relationship: transforms_into CCO:B0063763 ! BAZ1B_HUMAN-Phosphoserine705 relationship: transforms_into CCO:B0063764 ! BAZ1B_HUMAN-Phosphoserine708 relationship: transforms_into CCO:B0063765 ! BAZ1B_HUMAN-Phosphoserine716 relationship: transforms_into CCO:B0063766 ! BAZ1B_HUMAN-Phosphoserine947 relationship: transforms_into CCO:B0063767 ! BAZ1B_HUMAN-Phosphoserine1147 relationship: transforms_into CCO:B0063768 ! BAZ1B_HUMAN-Phosphoserine1315 relationship: transforms_into CCO:B0063769 ! BAZ1B_HUMAN-Phosphoserine1342 relationship: transforms_into CCO:B0063770 ! BAZ1B_HUMAN-Phosphoserine1468 [Term] id: CCO:B0059162 name: KLF15_HUMAN def: "Krueppel-like factor 15" [UniProtKB:Q9UIH9] synonym: "Kidney-enriched krueppel-like factor" EXACT [UniProtKB:Q9UIH9] xref: EMBL:AAH36733.1 xref: EMBL:BAA88561.1 xref: UniProtKB:Q9UIH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018413 ! KLF15_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0059163 name: ZN107_HUMAN def: "Zinc finger protein 107" [UniProtKB:Q9UII5] synonym: "Zinc finger protein 588" EXACT [UniProtKB:Q9UII5] synonym: "Zinc finger protein ZFD25" EXACT [UniProtKB:Q9UII5] xref: EMBL:AAH47243.1 xref: EMBL:BAA85623.1 xref: UniProtKB:Q9UII5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0011821 ! ZNF107_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059164 name: SIX4_HUMAN def: "Homeobox protein SIX4" [UniProtKB:Q9UIU6] synonym: "Sine oculis homeobox homolog 4" EXACT [UniProtKB:Q9UIU6] xref: EMBL:AAH98135.1 xref: EMBL:BAA86223.1 xref: UniProtKB:Q4V764 xref: UniProtKB:Q9UIU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019923 ! SIX4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002625 ! positive regulation of transcription relationship: transforms_into CCO:B0070564 ! SIX4_HUMAN-Phosphoserine619 [Term] id: CCO:B0059165 name: SPB13_HUMAN def: "Serpin B13" [UniProtKB:Q9UIV8] synonym: "HaCaT UV-repressible serpin" EXACT [UniProtKB:Q9UIV8] synonym: "Headpin" EXACT [UniProtKB:Q9UIV8] synonym: "Hurpin" EXACT [UniProtKB:Q9UIV8] synonym: "Proteinase inhibitor 13" EXACT [UniProtKB:Q9UIV8] xref: EMBL:AAD55765.1 xref: EMBL:AAF72879.1 xref: EMBL:AAI01822.1 xref: EMBL:CAA04935.2 xref: EMBL:CAA04936.2 xref: EMBL:CAA04937.1 xref: EMBL:CAC03569.1 xref: UniProtKB:Q3MII2 xref: UniProtKB:Q9HCX1 xref: UniProtKB:Q9UBW1 xref: UniProtKB:Q9UIV8 xref: UniProtKB:Q9UKG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020007 ! SERPINB13_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001246 ! regulation of proteolysis [Term] id: CCO:B0059166 name: VAX2_HUMAN def: "Ventral anterior homeobox 2" [UniProtKB:Q9UIW0] xref: EMBL:AAH06336.1 xref: EMBL:CAB56166.1 xref: UniProtKB:Q9UIW0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020438 ! VAX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004674 ! chromatin DNA binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059167 name: PLXA1_HUMAN def: "Plexin-A1 precursor" [UniProtKB:Q9UIW2] synonym: "Semaphorin receptor NOV" EXACT [UniProtKB:Q9UIW2] xref: EMBL:CAB57274.1 xref: UniProtKB:Q9UIW2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019446 ! PLXNA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069421 ! PLXA1_HUMAN-Phosphotyrosine122 [Term] id: CCO:B0059168 name: GP160_HUMAN def: "Probable G-protein coupled receptor 160" [UniProtKB:Q9UJ42] xref: EMBL:AAH00181.1 xref: EMBL:BAB89296.1 xref: EMBL:CAB55314.1 xref: UniProtKB:Q9UJ42 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017982 ! GPR160_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059169 name: Q9UJ49_HUMAN def: "Latrophilin-2" [UniProtKB:Q9UJ49] xref: EMBL:CAB60205.1 xref: UniProtKB:Q9UJ49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021279 ! LPHH1_human relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059170 name: TRM6_HUMAN def: "tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6" [UniProtKB:Q9UJA5] synonym: "tRNA(m1A58)-methyltransferase subunit TRM6" EXACT [UniProtKB:Q9UJA5] synonym: "tRNA(m1A58)MTase subunit TRM6" EXACT [UniProtKB:Q9UJA5] xref: EMBL:AAD27718.1 xref: EMBL:AAH01262.1 xref: EMBL:BAA86467.1 xref: EMBL:CAB55274.1 xref: UniProtKB:Q76P92 xref: UniProtKB:Q9BQV5 xref: UniProtKB:Q9UJA5 xref: UniProtKB:Q9ULR7 xref: UniProtKB:Q9Y2Z8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020362 ! TRMT6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018633 ! trm61-trm6-1 physical interaction relationship: participates_in CCO:P0000661 ! regulation of translational initiation relationship: transforms_into CCO:B0071582 ! TRM6_HUMAN-Phosphothreonine107 [Term] id: CCO:B0059171 name: METRN_HUMAN def: "Meteorin precursor" [UniProtKB:Q9UJH8] xref: EMBL:AAH00662.1 xref: EMBL:AAK61247.1 xref: EMBL:CAB56188.1 xref: UniProtKB:Q9UJH8 xref: UniProtKB:Q9UJH9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018607 ! METRN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0002950 ! positive regulation of axonogenesis [Term] id: CCO:B0059172 name: ZN643_HUMAN def: "Zinc finger protein 643" [UniProtKB:Q9UJL9] xref: EMBL:AAH17498.1 xref: EMBL:CAB70626.1 xref: UniProtKB:Q9UJL9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020871 ! ZNF643_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059173 name: ZN391_HUMAN def: "Zinc finger protein 391" [UniProtKB:Q9UJN7] xref: EMBL:CAB51755.1 xref: UniProtKB:Q9UJN7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020726 ! ZNF391_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072118 ! ZN391_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0072119 ! ZN391_HUMAN-Phosphothreonine49 [Term] id: CCO:B0059174 name: SALL4_HUMAN def: "Sal-like protein 4" [UniProtKB:Q9UJQ4] synonym: "Zinc finger protein SALL4" EXACT [UniProtKB:Q9UJQ4] xref: EMBL:AAI11715.1 xref: EMBL:AAO44950.1 xref: EMBL:CAB61485.1 xref: UniProtKB:Q540H3 xref: UniProtKB:Q9UJQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019835 ! SALL4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059175 name: LEF1_HUMAN def: "Lymphoid enhancer-binding factor 1" [UniProtKB:Q9UJU2] synonym: "LEF-1" EXACT [UniProtKB:Q9UJU2] synonym: "T cell-specific transcription factor 1-alpha" EXACT [UniProtKB:Q9UJU2] synonym: "TCF1-alpha" EXACT [UniProtKB:Q9UJU2] xref: EMBL:AAF13268.1 xref: EMBL:AAG01022.1 xref: EMBL:AAG26886.1 xref: EMBL:AAH50632.1 xref: UniProtKB:Q9HAZ0 xref: UniProtKB:Q9UJU2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018468 ! LEF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016320 ! lef1-tle1-1 direct interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: participates_in CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0059176 name: ZF112_HUMAN def: "Zinc finger protein 112 homolog" [UniProtKB:Q9UJU3] synonym: "Zfp-112" EXACT [UniProtKB:Q9UJU3] synonym: "Zinc finger protein 228" EXACT [UniProtKB:Q9UJU3] xref: EMBL:AAF12816.1 xref: EMBL:AAG23968.1 xref: UniProtKB:Q9HCA7 xref: UniProtKB:Q9UJU3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021025 ! ZFP112_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059177 name: DBNL_HUMAN def: "Drebrin-like protein" [UniProtKB:Q9UJU6] synonym: "Cervical mucin-associated protein" EXACT [UniProtKB:Q9UJU6] synonym: "Cervical SH3P7" EXACT [UniProtKB:Q9UJU6] synonym: "Drebrin-F" EXACT [UniProtKB:Q9UJU6] synonym: "HIP-55" EXACT [UniProtKB:Q9UJU6] synonym: "HPK1-interacting protein of 55 kDa" EXACT [UniProtKB:Q9UJU6] synonym: "SH3 domain-containing protein 7" EXACT [UniProtKB:Q9UJU6] xref: EMBL:AAF13701.1 xref: EMBL:AAF80228.1 xref: EMBL:AAF81273.1 xref: EMBL:AAG13120.1 xref: EMBL:AAG17262.2 xref: EMBL:AAH11677.1 xref: EMBL:AAH31687.1 xref: EMBL:BAB55065.1 xref: EMBL:CAG33448.1 xref: EMBL:EAL23770.1 xref: EMBL:EAW61132.1 xref: UniProtKB:A4D2I9 xref: UniProtKB:P84070 xref: UniProtKB:Q6IAI8 xref: UniProtKB:Q96F30 xref: UniProtKB:Q96K74 xref: UniProtKB:Q9HBN8 xref: UniProtKB:Q9NR72 xref: UniProtKB:Q9UJU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017526 ! DBNL_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: participates_in CCO:P0001131 ! Rac protein signal transduction relationship: transforms_into CCO:B0064635 ! DBNL_HUMAN-Phosphotyrosine162 relationship: transforms_into CCO:B0064636 ! DBNL_HUMAN-Phosphoserine178 relationship: transforms_into CCO:B0064637 ! DBNL_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0064638 ! DBNL_HUMAN-Phosphoserine269 relationship: transforms_into CCO:B0064639 ! DBNL_HUMAN-Phosphothreonine270 relationship: transforms_into CCO:B0064640 ! DBNL_HUMAN-Phosphoserine272 relationship: transforms_into CCO:B0064641 ! DBNL_HUMAN-Phosphoserine275 relationship: transforms_into CCO:B0064642 ! DBNL_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0064643 ! DBNL_HUMAN-Phosphothreonine291 relationship: transforms_into CCO:B0064644 ! DBNL_HUMAN-Phosphotyrosine334 relationship: transforms_into CCO:B0064645 ! DBNL_HUMAN-Phosphotyrosine344 [Term] id: CCO:B0059178 name: ZN229_HUMAN def: "Zinc finger protein 229" [UniProtKB:Q9UJW7] xref: EMBL:AAF07964.1 xref: EMBL:AAG23970.1 xref: EMBL:AAO45840.1 xref: EMBL:BAD92594.1 xref: UniProtKB:Q59FV2 xref: UniProtKB:Q86WL9 xref: UniProtKB:Q9UJW7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020668 ! ZNF229_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059179 name: ZN180_HUMAN def: "Zinc finger protein 180" [UniProtKB:Q9UJW8] synonym: "HHZ168" EXACT [UniProtKB:Q9UJW8] xref: EMBL:AAF07950.1 xref: EMBL:AAF71790.1 xref: UniProtKB:Q9P1U2 xref: UniProtKB:Q9UJW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020641 ! ZNF180_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072059 ! ZN180_HUMAN-Phosphoserine68 [Term] id: CCO:B0059180 name: SRTD3_HUMAN def: "SERTA domain-containing protein 3" [UniProtKB:Q9UJW9] synonym: "Replication protein-binding trans-activator" EXACT [UniProtKB:Q9UJW9] synonym: "RPA-binding trans-activator" EXACT [UniProtKB:Q9UJW9] xref: EMBL:AAF05761.1 xref: EMBL:AAH14061.1 xref: EMBL:AAH50643.1 xref: EMBL:BAG51975.1 xref: EMBL:EAW56966.1 xref: UniProtKB:B3KQB3 xref: UniProtKB:Q96CQ2 xref: UniProtKB:Q9UJW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020041 ! SERTAD3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015434 ! sertad3-ushbp1 physical interaction relationship: participates_in CCO:I0019415 ! ushbp1-sertad3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0059181 name: GDF2_HUMAN def: "Growth/differentiation factor 2 precursor" [UniProtKB:Q9UK05] synonym: "BMP-9" EXACT [UniProtKB:Q9UK05] synonym: "Bone morphogenetic protein 9" EXACT [UniProtKB:Q9UK05] synonym: "GDF-2" EXACT [UniProtKB:Q9UK05] xref: EMBL:AAD40309.1 xref: EMBL:AAD56960.1 xref: EMBL:AAH69643.1 xref: EMBL:AAH74921.1 xref: UniProtKB:Q9UK05 xref: UniProtKB:Q9Y571 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017905 ! GDF2_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0001003 ! negative regulation of endothelial cell migration relationship: participates_in CCO:P0001255 ! negative regulation of cell growth relationship: participates_in CCO:P0001270 ! BMP signaling pathway relationship: participates_in CCO:P0001714 ! activin receptor signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0059182 name: GBG8_HUMAN def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 precursor" [UniProtKB:Q9UK08] synonym: "Gamma-9" EXACT [UniProtKB:Q9UK08] xref: EMBL:AAF04569.1 xref: EMBL:AAH95514.1 xref: EMBL:AAM12589.1 xref: UniProtKB:Q4VBM5 xref: UniProtKB:Q9UK08 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017890 ! GNG8_human relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:B0059183 name: ZN225_HUMAN def: "Zinc finger protein 225" [UniProtKB:Q9UK10] xref: EMBL:AAF04107.1 xref: EMBL:AAF24967.1 xref: EMBL:AAF88105.1 xref: EMBL:AAI08913.1 xref: EMBL:BAD97197.1 xref: UniProtKB:Q53F12 xref: UniProtKB:Q9NS46 xref: UniProtKB:Q9UID8 xref: UniProtKB:Q9UK10 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020665 ! ZNF225_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072070 ! ZN225_HUMAN-Phosphothreonine283 [Term] id: CCO:B0059184 name: ZN223_HUMAN def: "Zinc finger protein 223" [UniProtKB:Q9UK11] xref: EMBL:AAF04105.1 xref: UniProtKB:Q9UK11 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020663 ! ZNF223_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059185 name: ZN222_HUMAN def: "Zinc finger protein 222" [UniProtKB:Q9UK12] xref: EMBL:AAF04104.1 xref: EMBL:AAF66075.1 xref: UniProtKB:Q9P1U5 xref: UniProtKB:Q9UK12 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020662 ! ZNF222_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059186 name: ZN221_HUMAN def: "Zinc finger protein 221" [UniProtKB:Q9UK13] xref: EMBL:AAF04103.1 xref: EMBL:AAF63029.1 xref: EMBL:AAI11982.1 xref: EMBL:AAI13427.1 xref: UniProtKB:Q2M2H2 xref: UniProtKB:Q9P1U8 xref: UniProtKB:Q9UK13 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020661 ! ZNF221_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059187 name: Q9UK67_HUMAN def: "70 kDa SHP-1L protein" [UniProtKB:Q9UK67] xref: EMBL:AAD53317.1 xref: UniProtKB:Q9UK67 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0059188 name: FEM1B_HUMAN def: "Protein fem-1 homolog B" [UniProtKB:Q9UK73] synonym: "F1A-alpha" EXACT [UniProtKB:Q9UK73] synonym: "Fem-1-like death receptor-binding protein alpha" EXACT [UniProtKB:Q9UK73] synonym: "FEM1-beta" EXACT [UniProtKB:Q9UK73] synonym: "FEM1b" EXACT [UniProtKB:Q9UK73] xref: EMBL:AAF05314.1 xref: EMBL:AAF69303.1 xref: EMBL:AAH10122.1 xref: EMBL:AAH14558.1 xref: EMBL:BAA23692.2 xref: EMBL:BAF82856.1 xref: EMBL:EAW77818.1 xref: UniProtKB:O43146 xref: UniProtKB:Q9UK73 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017773 ! FEM1B_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001425 ! death receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0059189 name: AKA11_HUMAN def: "A-kinase anchor protein 11" [UniProtKB:Q9UKA4] synonym: "A kinase anchor protein 220 kDa" EXACT [UniProtKB:Q9UKA4] synonym: "AKAP 220" EXACT [UniProtKB:Q9UKA4] synonym: "hAKAP220" EXACT [UniProtKB:Q9UKA4] synonym: "PRKA11" EXACT [UniProtKB:Q9UKA4] synonym: "Protein kinase A-anchoring protein 11" EXACT [UniProtKB:Q9UKA4] xref: EMBL:AAF07045.1 xref: EMBL:BAA31604.2 xref: EMBL:BAA92117.1 xref: EMBL:CAB89419.1 xref: UniProtKB:O75124 xref: UniProtKB:Q9NUK7 xref: UniProtKB:Q9UKA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016940 ! AKAP11_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001751 ! protein phosphatase 1 binding relationship: has_function CCO:F0008036 ! protein kinase A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0065495 ! AKA11_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0065496 ! AKA11_HUMAN-Phosphoserine433 relationship: transforms_into CCO:B0065497 ! AKA11_HUMAN-Phosphoserine448 relationship: transforms_into CCO:B0065498 ! AKA11_HUMAN-Phosphothreonine1100 relationship: transforms_into CCO:B0065499 ! AKA11_HUMAN-Phosphothreonine1104 relationship: transforms_into CCO:B0065500 ! AKA11_HUMAN-Phosphoserine1337 relationship: transforms_into CCO:B0065501 ! AKA11_HUMAN-Phosphoserine1340 [Term] id: CCO:B0059190 name: RCAN3_HUMAN def: "Calcipressin-3" [UniProtKB:Q9UKA8] synonym: "Down syndrome candidate region 1-like protein 2" EXACT [UniProtKB:Q9UKA8] synonym: "MCIP3" EXACT [UniProtKB:Q9UKA8] synonym: "Myocyte-enriched calcineurin-interacting protein 3" EXACT [UniProtKB:Q9UKA8] synonym: "Regulator of calcineurin 3" EXACT [UniProtKB:Q9UKA8] xref: EMBL:AAF01684.1 xref: EMBL:AAF01685.1 xref: EMBL:AAH35854.1 xref: EMBL:CAI21916.1 xref: UniProtKB:Q5TGC6 xref: UniProtKB:Q9NUC8 xref: UniProtKB:Q9UKA7 xref: UniProtKB:Q9UKA8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019655 ! RCAN3_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0004625 ! troponin I binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: transforms_into CCO:B0069835 ! RCAN3_HUMAN-Phosphotyrosine120 relationship: transforms_into CCO:B0069836 ! RCAN3_HUMAN-Phosphoserine148 relationship: transforms_into CCO:B0069837 ! RCAN3_HUMAN-Phosphoserine152 [Term] id: CCO:B0059191 name: GMEB2_HUMAN def: "Glucocorticoid modulatory element-binding protein 2" [UniProtKB:Q9UKD1] synonym: "DNA-binding protein p79PIF" EXACT [UniProtKB:Q9UKD1] synonym: "GMEB-2" EXACT [UniProtKB:Q9UKD1] synonym: "Parvovirus initiation factor p79" EXACT [UniProtKB:Q9UKD1] synonym: "PIF p79" EXACT [UniProtKB:Q9UKD1] xref: EMBL:AAD51351.1 xref: EMBL:AAH36305.1 xref: EMBL:BAA86583.1 xref: EMBL:CAB63765.1 xref: EMBL:CAI17956.1 xref: EMBL:CAI22265.1 xref: UniProtKB:Q5TDS0 xref: UniProtKB:Q9H431 xref: UniProtKB:Q9H4X7 xref: UniProtKB:Q9H4X8 xref: UniProtKB:Q9UF78 xref: UniProtKB:Q9UKD1 xref: UniProtKB:Q9ULF1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017939 ! GMEB2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018973 ! atxn1-gmeb2 physical interaction relationship: participates_in CCO:I0019077 ! atxn1-gmeb2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059192 name: PITC1_HUMAN def: "Cytoplasmic phosphatidylinositol transfer protein 1" [UniProtKB:Q9UKF7] synonym: "M-rdgB beta" EXACT [UniProtKB:Q9UKF7] synonym: "MrdgBbeta" EXACT [UniProtKB:Q9UKF7] synonym: "RdgBbeta" EXACT [UniProtKB:Q9UKF7] synonym: "Retinal degeneration B homolog beta" EXACT [UniProtKB:Q9UKF7] xref: EMBL:AAF06148.1 xref: EMBL:AAH07905.1 xref: EMBL:AAH67095.1 xref: UniProtKB:Q96I07 xref: UniProtKB:Q9UKF7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019401 ! PITPNC1_human relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0001978 ! phosphatidylinositol transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0069312 ! PITC1_HUMAN-Phosphoserine274 [Term] id: CCO:B0059193 name: BORG2_HUMAN def: "Cdc42 effector protein 3" [UniProtKB:Q9UKI2] synonym: "Binder of Rho GTPases 2" EXACT [UniProtKB:Q9UKI2] synonym: "MSE55-related Cdc42-binding protein" EXACT [UniProtKB:Q9UKI2] xref: EMBL:AAC71773.1 xref: EMBL:AAD16888.1 xref: EMBL:AAD48815.1 xref: EMBL:AAH19270.1 xref: EMBL:AAP35854.1 xref: EMBL:AAX93072.1 xref: EMBL:CAB66776.1 xref: UniProtKB:O95353 xref: UniProtKB:Q9UKI2 xref: UniProtKB:Q9UQJ0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017172 ! CDC42EP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015362 ! cdc42ep3-cdc42ep3 physical interaction relationship: participates_in CCO:I0020493 ! umps-cdc42ep3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000822 ! regulation of cell shape relationship: transforms_into CCO:B0063952 ! BORG2_HUMAN-Phosphoserine89 relationship: transforms_into CCO:B0063953 ! BORG2_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0063954 ! BORG2_HUMAN-Phosphoserine100 [Term] id: CCO:B0059194 name: RCOR1_HUMAN def: "REST corepressor 1" [UniProtKB:Q9UKL0] synonym: "Protein CoREST" EXACT [UniProtKB:Q9UKL0] xref: EMBL:AAF01498.1 xref: EMBL:AAH51003.1 xref: EMBL:AAH64495.1 xref: EMBL:BAA06686.1 xref: UniProtKB:Q15044 xref: UniProtKB:Q6P2I9 xref: UniProtKB:Q86VG5 xref: UniProtKB:Q9UKL0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019659 ! RCOR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018536 ! smarca4-rcor1 physical interaction relationship: participates_in CCO:I0018537 ! smarcc2-rcor1 physical interaction relationship: participates_in CCO:I0018538 ! hdac1-rcor1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0069843 ! RCOR1_HUMAN-Phosphoserine124 relationship: transforms_into CCO:B0069844 ! RCOR1_HUMAN-Phosphoserine257 relationship: transforms_into CCO:B0069845 ! RCOR1_HUMAN-Phosphoserine457 [Term] id: CCO:B0059195 name: O52A1_HUMAN def: "Olfactory receptor 52A1" [UniProtKB:Q9UKL2] synonym: "HPFH1OR" EXACT [UniProtKB:Q9UKL2] synonym: "Odorant receptor HOR3'beta4" EXACT [UniProtKB:Q9UKL2] synonym: "Olfactory receptor OR11-319" EXACT [UniProtKB:Q9UKL2] xref: EMBL:AAD51279.1 xref: EMBL:AAG42367.1 xref: EMBL:AAI11723.1 xref: EMBL:DAA04829.1 xref: UniProtKB:Q6IF31 xref: UniProtKB:Q9UKL2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019002 ! OR52A1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059196 name: MUC12_HUMAN def: "Mucin-12 precursor" [UniProtKB:Q9UKN1] synonym: "MUC-11" EXACT [UniProtKB:Q9UKN1] synonym: "MUC-12" EXACT [UniProtKB:Q9UKN1] synonym: "Mucin-11" EXACT [UniProtKB:Q9UKN1] xref: EMBL:AAD55678.1 xref: EMBL:AAD55679.1 xref: UniProtKB:Q9UKN0 xref: UniProtKB:Q9UKN1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018682 ! MUC12_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000466 ! regulation of cell growth [Term] id: CCO:B0059197 name: PRDM4_HUMAN def: "PR domain zinc finger protein 4" [UniProtKB:Q9UKN5] synonym: "PR domain-containing protein 4" EXACT [UniProtKB:Q9UKN5] xref: EMBL:AAD55249.2 xref: EMBL:AAH35581.1 xref: EMBL:CAB61401.1 xref: UniProtKB:Q9UFA6 xref: UniProtKB:Q9UKN5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019495 ! PRDM4_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059198 name: ITBP2_HUMAN def: "Integrin beta-1-binding protein 2" [UniProtKB:Q9UKP3] synonym: "Melusin" EXACT [UniProtKB:Q9UKP3] xref: EMBL:AAF01676.1 xref: EMBL:AAL36913.1 xref: UniProtKB:Q549J7 xref: UniProtKB:Q9UKP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018342 ! ITGB1BP2_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000934 ! Z disc relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059199 name: UR2R_HUMAN def: "Urotensin II receptor" [UniProtKB:Q9UKP6] synonym: "G-protein coupled receptor 14" EXACT [UniProtKB:Q9UKP6] synonym: "UR-II-R" EXACT [UniProtKB:Q9UKP6] xref: EMBL:AAD55578.1 xref: UniProtKB:Q9UKP6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020417 ! UTS2R_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000159 ! urotensin II receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059200 name: PACN3_HUMAN def: "Protein kinase C and casein kinase substrate in neurons protein 3" [UniProtKB:Q9UKS6] synonym: "Endophilin I" EXACT [UniProtKB:Q9UKS6] synonym: "SH3 domain-containing protein 6511" EXACT [UniProtKB:Q9UKS6] xref: EMBL:AAF04472.1 xref: EMBL:AAG31023.1 xref: EMBL:AAH07914.1 xref: EMBL:AAH11889.1 xref: EMBL:AAK29207.1 xref: EMBL:BAA91267.1 xref: UniProtKB:A6NH84 xref: UniProtKB:Q9H331 xref: UniProtKB:Q9NWV9 xref: UniProtKB:Q9UKS6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019285 ! PACSIN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017834 ! sos1-pacsin3-1 physical interaction relationship: participates_in CCO:I0017838 ! sos2-pacsin3-1 physical interaction relationship: participates_in CCO:I0017895 ! adam15-pacsin3-3 physical interaction relationship: participates_in CCO:I0018339 ! adam9-pacsin3-1 physical interaction relationship: participates_in CCO:I0018525 ! adam9-pacsin3-3 physical interaction relationship: participates_in CCO:I0018566 ! adam15-pacsin3-1 physical interaction relationship: participates_in CCO:I0019217 ! sos2-pacsin3-2 physical interaction relationship: participates_in CCO:I0019220 ! sos1-pacsin3-2 physical interaction relationship: participates_in CCO:P0002556 ! negative regulation of endocytosis relationship: transforms_into CCO:B0069045 ! PACN3_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0069046 ! PACN3_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0069047 ! PACN3_HUMAN-Phosphothreonine324 relationship: transforms_into CCO:B0069048 ! PACN3_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0069049 ! PACN3_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0069050 ! PACN3_HUMAN-Phosphoserine383 [Term] id: CCO:B0059201 name: ACSL6_HUMAN def: "Long-chain-fatty-acid--CoA ligase 6" [UniProtKB:Q9UKU0] synonym: "EC 6.2.1.3" EXACT [UniProtKB:Q9UKU0] synonym: "LACS 6" EXACT [UniProtKB:Q9UKU0] synonym: "Long-chain acyl-CoA synthetase 6" EXACT [UniProtKB:Q9UKU0] xref: EMBL:AAD17853.1 xref: EMBL:AAD47199.1 xref: EMBL:BAA74860.1 xref: UniProtKB:O94924 xref: UniProtKB:O95829 xref: UniProtKB:Q9UKU0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016905 ! ACSL6_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000867 ! long-chain-fatty-acid-CoA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000793 ! neuroblast proliferation [Term] id: CCO:B0059202 name: TRHDE_HUMAN def: "Thyrotropin-releasing hormone-degrading ectoenzyme" [UniProtKB:Q9UKU6] synonym: "EC 3.4.19.6" EXACT [UniProtKB:Q9UKU6] synonym: "PAP-II" EXACT [UniProtKB:Q9UKU6] synonym: "Pyroglutamyl-peptidase II" EXACT [UniProtKB:Q9UKU6] synonym: "Thyroliberinase" EXACT [UniProtKB:Q9UKU6] synonym: "TRH-DE" EXACT [UniProtKB:Q9UKU6] synonym: "TRH-degrading ectoenzyme" EXACT [UniProtKB:Q9UKU6] synonym: "TRH-specific aminopeptidase" EXACT [UniProtKB:Q9UKU6] xref: EMBL:AAF13141.1 xref: EMBL:AAQ89125.1 xref: UniProtKB:Q6UWJ4 xref: UniProtKB:Q9UKU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020352 ! TRHDE_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0000648 ! membrane alanyl aminopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003471 ! pyroglutamyl-peptidase II activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059203 name: ACAD8_HUMAN def: "Isobutyryl-CoA dehydrogenase, mitochondrial precursor" [UniProtKB:Q9UKU7] synonym: "ACAD-8" EXACT [UniProtKB:Q9UKU7] synonym: "Activator-recruited cofactor 42 kDa component" EXACT [UniProtKB:Q9UKU7] synonym: "Acyl-CoA dehydrogenase family member 8" EXACT [UniProtKB:Q9UKU7] synonym: "ARC42" EXACT [UniProtKB:Q9UKU7] synonym: "EC 1.3.99.-" EXACT [UniProtKB:Q9UKU7] xref: EMBL:AAF12736.1 xref: EMBL:AAF97922.1 xref: EMBL:AAH01964.1 xref: EMBL:BAA91109.1 xref: UniProtKB:Q9BUS8 xref: UniProtKB:Q9UKU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016880 ! ACAD8_human relationship: has_function CCO:F0000480 ! acyl-CoA dehydrogenase activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059204 name: ANGL2_HUMAN def: "Angiopoietin-related protein 2 precursor" [UniProtKB:Q9UKU9] synonym: "Angiopoietin-like 2" EXACT [UniProtKB:Q9UKU9] xref: EMBL:AAD55357.1 xref: EMBL:AAH12368.1 xref: EMBL:AAQ88641.1 xref: EMBL:CAI39725.1 xref: UniProtKB:Q5JT58 xref: UniProtKB:Q9UKU9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016966 ! ANGPTL2_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059205 name: ACINU_HUMAN def: "Apoptotic chromatin condensation inducer in the nucleus" [UniProtKB:Q9UKV3] synonym: "Acinus" EXACT [UniProtKB:Q9UKV3] xref: EMBL:AAD56724.1 xref: EMBL:AAD56725.1 xref: EMBL:AAD56726.1 xref: EMBL:BAA31645.2 xref: EMBL:CAB43681.2 xref: EMBL:CAD62309.1 xref: UniProtKB:O75158 xref: UniProtKB:Q9UG91 xref: UniProtKB:Q9UKV1 xref: UniProtKB:Q9UKV2 xref: UniProtKB:Q9UKV3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016897 ! ACIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020393 ! pafah1b2-acin1 physical interaction relationship: participates_in CCO:I0020506 ! akr1c3-acin1 physical interaction relationship: participates_in CCO:I0020563 ! btbd10-acin1 physical interaction relationship: participates_in CCO:P0001251 ! apoptotic chromosome condensation relationship: participates_in CCO:P0002471 ! positive regulation of monocyte differentiation relationship: transforms_into CCO:B0065320 ! ACINU_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0065321 ! ACINU_HUMAN-Phosphoserine169 relationship: transforms_into CCO:B0065322 ! ACINU_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0065323 ! ACINU_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0065324 ! ACINU_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0065325 ! ACINU_HUMAN-Phosphoserine229 relationship: transforms_into CCO:B0065326 ! ACINU_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0065327 ! ACINU_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0065328 ! ACINU_HUMAN-Phosphothreonine254 relationship: transforms_into CCO:B0065329 ! ACINU_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0065330 ! ACINU_HUMAN-Phosphothreonine269 relationship: transforms_into CCO:B0065331 ! ACINU_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0065332 ! ACINU_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0065333 ! ACINU_HUMAN-Phosphoserine365 relationship: transforms_into CCO:B0065334 ! ACINU_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0065335 ! ACINU_HUMAN-Phosphoserine386 relationship: transforms_into CCO:B0065336 ! ACINU_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0065337 ! ACINU_HUMAN-Phosphothreonine393 relationship: transforms_into CCO:B0065338 ! ACINU_HUMAN-Phosphothreonine408 relationship: transforms_into CCO:B0065339 ! ACINU_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0065340 ! ACINU_HUMAN-Phosphothreonine414 relationship: transforms_into CCO:B0065341 ! ACINU_HUMAN-Phosphoserine424 relationship: transforms_into CCO:B0065342 ! ACINU_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0065343 ! ACINU_HUMAN-Phosphoserine434 relationship: transforms_into CCO:B0065344 ! ACINU_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0065345 ! ACINU_HUMAN-Phosphoserine478 relationship: transforms_into CCO:B0065346 ! ACINU_HUMAN-Phosphoserine490 relationship: transforms_into CCO:B0065347 ! ACINU_HUMAN-Phosphotyrosine512 relationship: transforms_into CCO:B0065348 ! ACINU_HUMAN-Phosphoserine561 relationship: transforms_into CCO:B0065349 ! ACINU_HUMAN-Phosphoserine655 relationship: transforms_into CCO:B0065350 ! ACINU_HUMAN-Phosphoserine657 relationship: transforms_into CCO:B0065351 ! ACINU_HUMAN-Phosphoserine661 relationship: transforms_into CCO:B0065352 ! ACINU_HUMAN-Phosphoserine676 relationship: transforms_into CCO:B0065353 ! ACINU_HUMAN-Phosphothreonine682 relationship: transforms_into CCO:B0065354 ! ACINU_HUMAN-Phosphoserine710 relationship: transforms_into CCO:B0065355 ! ACINU_HUMAN-Phosphoserine714 relationship: transforms_into CCO:B0065356 ! ACINU_HUMAN-Phosphothreonine720 relationship: transforms_into CCO:B0065357 ! ACINU_HUMAN-Phosphoserine729 relationship: transforms_into CCO:B0065358 ! ACINU_HUMAN-Phosphoserine814 relationship: transforms_into CCO:B0065359 ! ACINU_HUMAN-Phosphoserine815 relationship: transforms_into CCO:B0065360 ! ACINU_HUMAN-Phosphothreonine830 relationship: transforms_into CCO:B0065361 ! ACINU_HUMAN-Phosphoserine838 relationship: transforms_into CCO:B0065362 ! ACINU_HUMAN-Phosphothreonine840 relationship: transforms_into CCO:B0065363 ! ACINU_HUMAN-Phosphoserine895 relationship: transforms_into CCO:B0065364 ! ACINU_HUMAN-Phosphoserine898 relationship: transforms_into CCO:B0065365 ! ACINU_HUMAN-Phosphothreonine976 relationship: transforms_into CCO:B0065366 ! ACINU_HUMAN-Phosphothreonine978 relationship: transforms_into CCO:B0065367 ! ACINU_HUMAN-Phosphoserine981 relationship: transforms_into CCO:B0065368 ! ACINU_HUMAN-Phosphoserine983 relationship: transforms_into CCO:B0065369 ! ACINU_HUMAN-Phosphoserine1004 relationship: transforms_into CCO:B0065370 ! ACINU_HUMAN-Phosphoserine1176 relationship: transforms_into CCO:B0065371 ! ACINU_HUMAN-Phosphoserine1178 relationship: transforms_into CCO:B0065372 ! ACINU_HUMAN-Phosphoserine1180 relationship: transforms_into CCO:B0065373 ! ACINU_HUMAN-Phosphoserine1284 [Term] id: CCO:B0059206 name: AMFR2_HUMAN def: "Autocrine motility factor receptor, isoform 2" [UniProtKB:Q9UKV5] synonym: "AMF receptor, isoform 2" EXACT [UniProtKB:Q9UKV5] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9UKV5] synonym: "gp78" EXACT [UniProtKB:Q9UKV5] synonym: "RING finger protein 45" EXACT [UniProtKB:Q9UKV5] xref: EMBL:AAD56722.1 xref: EMBL:AAH69197.1 xref: UniProtKB:Q8IZ70 xref: UniProtKB:Q9UKV5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016958 ! AMFR_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000050 ! integral to membrane of membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: participates_in CCO:P0001358 ! endoplasmic reticulum unfolded protein response relationship: transforms_into CCO:B0065613 ! AMFR2_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0065614 ! AMFR2_HUMAN-Phosphoserine523 relationship: transforms_into CCO:B0065615 ! AMFR2_HUMAN-Phosphoserine542 [Term] id: CCO:B0059207 name: VAV3_HUMAN def: "Guanine nucleotide exchange factor VAV3" [UniProtKB:Q9UKW4] synonym: "VAV-3" EXACT [UniProtKB:Q9UKW4] xref: EMBL:AAC79695.1 xref: EMBL:AAD20348.1 xref: EMBL:AAD20349.1 xref: UniProtKB:O95230 xref: UniProtKB:Q9UKW4 xref: UniProtKB:Q9Y5X8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020435 ! VAV3_human relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:B0059208 name: ELF5_HUMAN def: "ETS-related transcription factor Elf-5" [UniProtKB:Q9UKW6] synonym: "E74-like factor 5" EXACT [UniProtKB:Q9UKW6] synonym: "Epithelium-restricted ESE-1-related Ets factor" EXACT [UniProtKB:Q9UKW6] synonym: "Epithelium-specific Ets transcription factor 2" EXACT [UniProtKB:Q9UKW6] synonym: "ESE-2" EXACT [UniProtKB:Q9UKW6] xref: EMBL:AAC79755.1 xref: EMBL:AAD22960.1 xref: EMBL:AAD22961.1 xref: EMBL:AAH29743.1 xref: EMBL:BAC11101.1 xref: UniProtKB:O95175 xref: UniProtKB:Q8N2K9 xref: UniProtKB:Q96QY3 xref: UniProtKB:Q9UKW5 xref: UniProtKB:Q9UKW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017685 ! ELF5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008960 ! elf5-rps15a physical interaction relationship: participates_in CCO:I0015355 ! elf5-sirt6 physical interaction relationship: participates_in CCO:I0017528 ! elf5-ubqln4 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059209 name: CDV3_HUMAN def: "Protein CDV3 homolog" [UniProtKB:Q9UKY7] xref: EMBL:AAF02423.1 xref: EMBL:AAH07338.1 xref: UniProtKB:Q96IP9 xref: UniProtKB:Q9UKY7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017322 ! CDV3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000815 ! cell proliferation relationship: transforms_into CCO:B0064241 ! CDV3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0064242 ! CDV3_HUMAN-Phosphothreonine4 relationship: transforms_into CCO:B0064243 ! CDV3_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0064244 ! CDV3_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0064245 ! CDV3_HUMAN-Phosphotyrosine95 relationship: transforms_into CCO:B0064246 ! CDV3_HUMAN-Phosphothreonine182 relationship: transforms_into CCO:B0064247 ! CDV3_HUMAN-Phosphotyrosine190 relationship: transforms_into CCO:B0064248 ! CDV3_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0064249 ! CDV3_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0064250 ! CDV3_HUMAN-Phosphotyrosine244 [Term] id: CCO:B0059210 name: CB029_HUMAN def: "Uncharacterized protein C2orf29" [UniProtKB:Q9UKZ1] xref: EMBL:AAF02418.1 xref: EMBL:AAH18664.2 xref: EMBL:AAH64421.1 xref: EMBL:AAY15088.1 xref: UniProtKB:Q6P2M9 xref: UniProtKB:Q8N681 xref: UniProtKB:Q9UKZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017246 ! C2orf29_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059211 name: TEN1_HUMAN def: "Teneurin-1" [UniProtKB:Q9UKZ4] synonym: "Protein Odd Oz/ten-m homolog 1" EXACT [UniProtKB:Q9UKZ4] synonym: "Ten-1" EXACT [UniProtKB:Q9UKZ4] synonym: "Ten-m1" EXACT [UniProtKB:Q9UKZ4] synonym: "Tenascin-M1" EXACT [UniProtKB:Q9UKZ4] xref: EMBL:AAF04723.1 xref: EMBL:CAI42154.1 xref: EMBL:CAI42710.1 xref: EMBL:CAI42721.1 xref: EMBL:CAI42742.1 xref: EMBL:CAI42975.1 xref: EMBL:CAI43065.1 xref: UniProtKB:Q5JZ17 xref: UniProtKB:Q9UKZ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020229 ! ODZ1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation relationship: transforms_into CCO:B0071324 ! TEN1_HUMAN-Phosphoserine2580 [Term] id: CCO:B0059212 name: Q9UL14_HUMAN def: "Olfactory receptor 17-1" [UniProtKB:Q9UL14] xref: EMBL:AAF03263.1 xref: UniProtKB:Q9UL14 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021280 ! OR17-1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059213 name: TBX21_HUMAN def: "T-box transcription factor TBX21" [UniProtKB:Q9UL17] synonym: "T-box protein 21" EXACT [UniProtKB:Q9UL17] synonym: "T-cell-specific T-box transcription factor T-bet" EXACT [UniProtKB:Q9UL17] synonym: "Transcription factor TBLYM" EXACT [UniProtKB:Q9UL17] xref: EMBL:AAF00055.1 xref: EMBL:AAF61243.1 xref: EMBL:AAH39739.1 xref: UniProtKB:Q9UL17 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020196 ! TBX21_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002815 ! positive regulation of isotype switching to IgG isotypes [Term] id: CCO:B0059214 name: RAB21_HUMAN def: "Ras-related protein Rab-21" [UniProtKB:Q9UL25] xref: EMBL:AAF00048.1 xref: EMBL:AAH21901.1 xref: EMBL:AAH92475.1 xref: EMBL:BAA07682.1 xref: UniProtKB:Q14466 xref: UniProtKB:Q569H3 xref: UniProtKB:Q9UL25 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019579 ! RAB21_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069674 ! RAB21_HUMAN-N-acetylalanine2 [Term] id: CCO:B0059215 name: Q9UL31_HUMAN def: "GTP-binding protein RAB2B" [UniProtKB:Q9UL31] xref: EMBL:AAF00042.1 xref: UniProtKB:Q9UL31 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019586 ! RAB2B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0059216 name: ZN236_HUMAN def: "Zinc finger protein 236" [UniProtKB:Q9UL36] xref: EMBL:AAD55328.1 xref: EMBL:AAD55329.1 xref: UniProtKB:Q9UL36 xref: UniProtKB:Q9UL37 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020674 ! ZNF236_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059217 name: TCFL5_HUMAN def: "Transcription factor-like 5 protein" [UniProtKB:Q9UL49] synonym: "Cha transcription factor" EXACT [UniProtKB:Q9UL49] synonym: "E2BP-1" EXACT [UniProtKB:Q9UL49] synonym: "HPV-16 E2-binding protein 1" EXACT [UniProtKB:Q9UL49] xref: EMBL:AAD53986.1 xref: EMBL:BAA36557.1 xref: EMBL:CAC12752.2 xref: EMBL:CAC24700.1 xref: UniProtKB:O94771 xref: UniProtKB:Q9BYW0 xref: UniProtKB:Q9UL49 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020218 ! TCFL5_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002045 ! regulation of cell proliferation relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: participates_in CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:B0059218 name: ZN215_HUMAN def: "Zinc finger protein 215" [UniProtKB:Q9UL58] synonym: "BAZ 2" EXACT [UniProtKB:Q9UL58] synonym: "BWSCR2-associated zinc finger protein 2" EXACT [UniProtKB:Q9UL58] synonym: "Zinc finger protein with KRAB and SCAN domains 11" EXACT [UniProtKB:Q9UL58] xref: EMBL:AAF00005.1 xref: UniProtKB:Q9UL58 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020658 ! ZNF215_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059219 name: ZN214_HUMAN def: "Zinc finger protein 214" [UniProtKB:Q9UL59] synonym: "BAZ 1" EXACT [UniProtKB:Q9UL59] synonym: "BWSCR2-associated zinc finger protein 1" EXACT [UniProtKB:Q9UL59] xref: EMBL:AAF00004.1 xref: UniProtKB:Q9UL59 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020657 ! ZNF214_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059220 name: Q9ULA3_HUMAN xref: UniProtKB:Q9ULA3 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059221 name: RAB23_HUMAN def: "Ras-related protein Rab-23" [UniProtKB:Q9ULC3] xref: EMBL:AAF29101.1 xref: EMBL:AAH15021.1 xref: EMBL:AAM21099.1 xref: EMBL:AAT79492.1 xref: EMBL:BAA87324.1 xref: EMBL:BAB40309.1 xref: EMBL:CAI21564.1 xref: UniProtKB:Q8NI06 xref: UniProtKB:Q9P023 xref: UniProtKB:Q9ULC3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019580 ! RAB23_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0002578 ! negative regulation of proteolysis [Term] id: CCO:B0059222 name: ZN777_HUMAN def: "Zinc finger protein 777" [UniProtKB:Q9ULD5] xref: EMBL:AAH23985.2 xref: EMBL:BAA86599.1 xref: EMBL:BAC11033.1 xref: UniProtKB:Q8N2R2 xref: UniProtKB:Q8N659 xref: UniProtKB:Q9ULD5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020933 ! ZNF777_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072240 ! ZN777_HUMAN-Phosphoserine554 [Term] id: CCO:B0059223 name: KCNH3_HUMAN def: "Potassium voltage-gated channel subfamily H member 3" [UniProtKB:Q9ULD8] synonym: "BEC1" EXACT [UniProtKB:Q9ULD8] synonym: "Brain-specific eag-like channel 1" EXACT [UniProtKB:Q9ULD8] synonym: "ELK channel 2" EXACT [UniProtKB:Q9ULD8] synonym: "ELK2" EXACT [UniProtKB:Q9ULD8] synonym: "Ether-a-go-go-like potassium channel 2" EXACT [UniProtKB:Q9ULD8] synonym: "Voltage-gated potassium channel subunit Kv12.2" EXACT [UniProtKB:Q9ULD8] xref: EMBL:BAA83590.1 xref: EMBL:BAA86596.1 xref: UniProtKB:Q9ULD8 xref: UniProtKB:Q9UQ06 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018392 ! KCNH3_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059224 name: ARMS_HUMAN def: "Ankyrin repeat-rich membrane spanning protein" [UniProtKB:Q9ULH0] synonym: "Kinase D-interacting substrate of 220 kDa" EXACT [UniProtKB:Q9ULH0] xref: EMBL:AAH94714.1 xref: EMBL:AAI30611.1 xref: EMBL:BAA86564.2 xref: EMBL:BAB14285.1 xref: EMBL:BAB14728.1 xref: EMBL:CAB63746.1 xref: EMBL:CAB70807.1 xref: EMBL:CAE45935.1 xref: UniProtKB:A1L4N4 xref: UniProtKB:Q4VC08 xref: UniProtKB:Q6MZU2 xref: UniProtKB:Q9H889 xref: UniProtKB:Q9H9E4 xref: UniProtKB:Q9NT37 xref: UniProtKB:Q9UF42 xref: UniProtKB:Q9ULH0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017044 ! ARMS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0063598 ! ARMS_HUMAN-Phosphoserine918 relationship: transforms_into CCO:B0063599 ! ARMS_HUMAN-Phosphoserine1294 relationship: transforms_into CCO:B0063600 ! ARMS_HUMAN-Phosphoserine1359 relationship: transforms_into CCO:B0063601 ! ARMS_HUMAN-Phosphoserine1362 relationship: transforms_into CCO:B0063602 ! ARMS_HUMAN-Phosphoserine1365 relationship: transforms_into CCO:B0063603 ! ARMS_HUMAN-Phosphoserine1521 relationship: transforms_into CCO:B0063604 ! ARMS_HUMAN-Phosphoserine1526 [Term] id: CCO:B0059225 name: DDEF1_HUMAN def: "130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein" [UniProtKB:Q9ULH1] synonym: "ADP-ribosylation factor-directed GTPase-activating protein 1" EXACT [UniProtKB:Q9ULH1] synonym: "ARF GTPase-activating protein 1" EXACT [UniProtKB:Q9ULH1] synonym: "DEF-1" EXACT [UniProtKB:Q9ULH1] synonym: "Development and differentiation-enhancing factor 1" EXACT [UniProtKB:Q9ULH1] synonym: "Differentiation-enhancing factor 1" EXACT [UniProtKB:Q9ULH1] synonym: "PIP2-dependent ARF1 GAP" EXACT [UniProtKB:Q9ULH1] xref: EMBL:BAA86563.1 xref: EMBL:CAD97831.1 xref: UniProtKB:Q9ULH1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017539 ! DDEF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018428 ! hck-ddef1-1 physical interaction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0064685 ! DDEF1_HUMAN-Phosphoserine839 relationship: transforms_into CCO:B0064686 ! DDEF1_HUMAN-Phosphoserine843 relationship: transforms_into CCO:B0064687 ! DDEF1_HUMAN-Phosphoserine1008 relationship: transforms_into CCO:B0064688 ! DDEF1_HUMAN-Phosphoserine1027 [Term] id: CCO:B0059226 name: MKL2_HUMAN def: "MKL/myocardin-like protein 2" [UniProtKB:Q9ULH7] synonym: "Megakaryoblastic leukemia 2" EXACT [UniProtKB:Q9ULH7] synonym: "MRTF-B" EXACT [UniProtKB:Q9ULH7] synonym: "Myocardin-related transcription factor B" EXACT [UniProtKB:Q9ULH7] xref: EMBL:AAH47761.1 xref: EMBL:AAQ82435.1 xref: EMBL:BAA86557.2 xref: EMBL:BAC04200.1 xref: EMBL:CAH18657.1 xref: UniProtKB:A6ND53 xref: UniProtKB:Q68CT1 xref: UniProtKB:Q6UB16 xref: UniProtKB:Q86WW2 xref: UniProtKB:Q8N226 xref: UniProtKB:Q9ULH7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018632 ! MKL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017672 ! mkl2-srf-1 physical interaction relationship: participates_in CCO:I0018008 ! mkl2-mkl2-1 physical interaction relationship: participates_in CCO:I0018009 ! mkl2-mkl1-1 physical interaction relationship: participates_in CCO:I0018303 ! srf-mkl2-1 physical interaction relationship: participates_in CCO:I0019355 ! srf-mlk2-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0068215 ! MKL2_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0068216 ! MKL2_HUMAN-Phosphothreonine367 relationship: transforms_into CCO:B0068217 ! MKL2_HUMAN-Phosphothreonine370 relationship: transforms_into CCO:B0068218 ! MKL2_HUMAN-Phosphoserine921 [Term] id: CCO:B0059227 name: ZMIZ1_HUMAN def: "Zinc finger MIZ domain-containing protein 1" [UniProtKB:Q9ULJ6] synonym: "PIAS-like protein Zimp10" EXACT [UniProtKB:Q9ULJ6] synonym: "Retinoic acid-induced protein 17" EXACT [UniProtKB:Q9ULJ6] xref: EMBL:AAP13542.1 xref: EMBL:BAA86538.2 xref: UniProtKB:Q7Z7E6 xref: UniProtKB:Q9ULJ6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020614 ! ZMIZ1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0017287 ! cntnap2-kiaa1224 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059228 name: PKHG1_HUMAN def: "Pleckstrin homology domain-containing family G member 1" [UniProtKB:Q9ULL1] xref: EMBL:BAA86523.1 xref: EMBL:CAI12939.1 xref: UniProtKB:Q5T1F2 xref: UniProtKB:Q9ULL1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019413 ! PLEKHG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0069341 ! PKHG1_HUMAN-Phosphoserine1150 relationship: transforms_into CCO:B0069342 ! PKHG1_HUMAN-Phosphoserine1192 relationship: transforms_into CCO:B0069343 ! PKHG1_HUMAN-Phosphoserine1245 [Term] id: CCO:B0059229 name: ZN490_HUMAN def: "Zinc finger protein 490" [UniProtKB:Q9ULM2] xref: EMBL:AAH38586.1 xref: EMBL:BAA86512.1 xref: UniProtKB:Q9ULM2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020774 ! ZNF490_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017484 ! dtnbp1-znf490 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059230 name: YETS2_HUMAN def: "YEATS domain-containing protein 2" [UniProtKB:Q9ULM3] xref: EMBL:AAH82270.1 xref: EMBL:BAA86511.1 xref: EMBL:BAA91487.1 xref: UniProtKB:Q641P6 xref: UniProtKB:Q9NW96 xref: UniProtKB:Q9ULM3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020513 ! YEATS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071922 ! YETS2_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0071923 ! YETS2_HUMAN-Phosphoserine144 relationship: transforms_into CCO:B0071924 ! YETS2_HUMAN-Phosphoserine447 relationship: transforms_into CCO:B0071925 ! YETS2_HUMAN-Phosphoserine465 relationship: transforms_into CCO:B0071926 ! YETS2_HUMAN-Phosphoserine519 [Term] id: CCO:B0059231 name: TBC24_HUMAN def: "TBC1 domain family member 24" [UniProtKB:Q9ULP9] xref: EMBL:AAI12390.1 xref: EMBL:AAI27015.1 xref: EMBL:AAI27016.1 xref: EMBL:BAA86485.1 xref: UniProtKB:A0JNW3 xref: UniProtKB:Q2KJ08 xref: UniProtKB:Q9ULP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020166 ! TBC1D24_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059232 name: PAI2B_HUMAN def: "Polyadenylate-binding protein-interacting protein 2B" [UniProtKB:Q9ULR5] synonym: "PABP-interacting protein 2B" EXACT [UniProtKB:Q9ULR5] synonym: "PAIP-2B" EXACT [UniProtKB:Q9ULR5] synonym: "Poly(A)-binding protein-interacting protein 2B" EXACT [UniProtKB:Q9ULR5] xref: EMBL:BAA86469.1 xref: UniProtKB:Q9ULR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019290 ! PAIP2B_human relationship: has_function CCO:F0000118 ! translation repressor activity, nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002630 ! negative regulation of translational initiation [Term] id: CCO:B0059233 name: FZD4_HUMAN def: "Frizzled-4 precursor" [UniProtKB:Q9ULV1] synonym: "CD344 antigen" EXACT [UniProtKB:Q9ULV1] synonym: "Fz-4" EXACT [UniProtKB:Q9ULV1] synonym: "FzE4" EXACT [UniProtKB:Q9ULV1] synonym: "hFz4" EXACT [UniProtKB:Q9ULV1] xref: EMBL:AAI14528.1 xref: EMBL:AAI14623.1 xref: EMBL:AAR23924.1 xref: EMBL:BAA86286.1 xref: UniProtKB:Q14C97 xref: UniProtKB:Q6S9E4 xref: UniProtKB:Q9ULV1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017853 ! FZD4_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001271 ! non-G-protein coupled 7TM receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005719 ! Wnt receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0059234 name: CBLC_HUMAN def: "Signal transduction protein CBL-C" [UniProtKB:Q9ULV8] synonym: "CBL-3" EXACT [UniProtKB:Q9ULV8] synonym: "RING finger protein 57" EXACT [UniProtKB:Q9ULV8] synonym: "SH3-binding protein CBL-C" EXACT [UniProtKB:Q9ULV8] xref: EMBL:AAD34341.1 xref: EMBL:AAD34342.1 xref: EMBL:AAH28915.1 xref: EMBL:BAA86298.1 xref: UniProtKB:Q8N1E5 xref: UniProtKB:Q9ULV8 xref: UniProtKB:Q9Y5Z2 xref: UniProtKB:Q9Y5Z3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017247 ! CBLC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000717 ! negative regulation of epidermal growth factor receptor activity relationship: transforms_into CCO:B0064093 ! CBLC_HUMAN-Phosphoserine40 [Term] id: CCO:B0059235 name: ABT1_HUMAN def: "Activator of basal transcription 1" [UniProtKB:Q9ULW3] synonym: "Basal transcriptional activator" EXACT [UniProtKB:Q9ULW3] synonym: "hABT1" EXACT [UniProtKB:Q9ULW3] xref: EMBL:AAH48812.1 xref: EMBL:AAH66313.1 xref: EMBL:BAA86886.1 xref: EMBL:CAC40824.1 xref: UniProtKB:Q9ULW3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016877 ! ABT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059236 name: RAB26_HUMAN def: "Ras-related protein Rab-26" [UniProtKB:Q9ULW5] xref: EMBL:AAH66913.1 xref: EMBL:AAM21100.1 xref: EMBL:BAA84707.1 xref: UniProtKB:Q6NXS7 xref: UniProtKB:Q9ULW5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019583 ! RAB26_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001150 ! intrinsic to plasma membrane relationship: participates_in CCO:I0018234 ! gch1-rab26-1 physical interaction relationship: participates_in CCO:I0018624 ! gch1-rab26 physical interaction relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0059237 name: Q9ULW9_HUMAN def: "3',5'-cyclic nucleotide phosphodiesterase 10A2" [UniProtKB:Q9ULW9] xref: EMBL:BAA84467.1 xref: UniProtKB:Q9ULW9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021281 ! PDE10A2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059238 name: APEL_HUMAN def: "Apelin precursor" [UniProtKB:Q9ULZ1] synonym: "APJ endogenous ligand" EXACT [UniProtKB:Q9ULZ1] xref: EMBL:AAF25815.1 xref: EMBL:AAH21104.2 xref: EMBL:BAA84975.1 xref: EMBL:CAI95697.1 xref: UniProtKB:Q4VY08 xref: UniProtKB:Q8WU89 xref: UniProtKB:Q9ULZ1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016985 ! APLN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065689 ! APEL_HUMAN-Pyrrolidone carboxylic acid65 [Term] id: CCO:B0059239 name: STAP1_HUMAN def: "Signal-transducing adaptor protein 1" [UniProtKB:Q9ULZ2] synonym: "BCR downstream-signaling protein 1" EXACT [UniProtKB:Q9ULZ2] synonym: "Docking protein BRDG1" EXACT [UniProtKB:Q9ULZ2] synonym: "STAP-1" EXACT [UniProtKB:Q9ULZ2] synonym: "Stem cell adaptor protein 1" EXACT [UniProtKB:Q9ULZ2] xref: EMBL:AAH14958.1 xref: EMBL:BAA85311.1 xref: UniProtKB:Q9ULZ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020064 ! STAP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0070963 ! STAP1_HUMAN-Phosphotyrosine168 relationship: transforms_into CCO:B0070964 ! STAP1_HUMAN-Phosphoserine196 [Term] id: CCO:B0059240 name: Q9UM77_HUMAN def: "Olfactory receptor 17-210" [UniProtKB:Q9UM77] xref: EMBL:AAC99555.1 xref: UniProtKB:Q9UM77 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021282 ! OR1E3P_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059241 name: CLC4A_HUMAN def: "C-type lectin domain family 4 member A" [UniProtKB:Q9UMR7] synonym: "C-type lectin DDB27" EXACT [UniProtKB:Q9UMR7] synonym: "C-type lectin superfamily member 6" EXACT [UniProtKB:Q9UMR7] synonym: "Dendritic cell immunoreceptor" EXACT [UniProtKB:Q9UMR7] synonym: "Lectin-like immunoreceptor" EXACT [UniProtKB:Q9UMR7] xref: EMBL:AAF14348.1 xref: EMBL:AAF75560.1 xref: EMBL:AAG35593.1 xref: EMBL:AAH74822.1 xref: EMBL:AAH74874.1 xref: EMBL:AAI17440.1 xref: EMBL:AAI17442.1 xref: EMBL:AAL56016.1 xref: EMBL:CAB54001.1 xref: UniProtKB:Q17R69 xref: UniProtKB:Q8WXW9 xref: UniProtKB:Q9H2Z9 xref: UniProtKB:Q9NS33 xref: UniProtKB:Q9UI34 xref: UniProtKB:Q9UMR7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017378 ! CLEC4A_human relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0059242 name: PHTF1_HUMAN def: "Putative homeodomain transcription factor 1" [UniProtKB:Q9UMS5] xref: EMBL:AAH02447.1 xref: EMBL:CAB51572.1 xref: EMBL:CAH72503.1 xref: EMBL:CAH72504.1 xref: EMBL:CAI22547.1 xref: EMBL:CAI22549.1 xref: UniProtKB:Q5VWP7 xref: UniProtKB:Q5VWP8 xref: UniProtKB:Q9BUP2 xref: UniProtKB:Q9H1X8 xref: UniProtKB:Q9UMS5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019387 ! PHTF1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059243 name: NENF_HUMAN def: "Neudesin precursor" [UniProtKB:Q9UMX5] synonym: "Cell immortalization-related protein 2" EXACT [UniProtKB:Q9UMX5] synonym: "Neuron-derived neurotrophic factor" EXACT [UniProtKB:Q9UMX5] synonym: "Secreted protein of unknown function" EXACT [UniProtKB:Q9UMX5] synonym: "SPUF protein" EXACT [UniProtKB:Q9UMX5] xref: EMBL:AAD51419.1 xref: EMBL:AAH08823.1 xref: EMBL:AAX07829.1 xref: EMBL:BAD72063.1 xref: EMBL:BAD96855.1 xref: EMBL:EAW93389.1 xref: UniProtKB:A1KYQ8 xref: UniProtKB:Q53FZ6 xref: UniProtKB:Q5TM90 xref: UniProtKB:Q9UMX5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018753 ! NENF_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0002211 ! positive regulation of MAPKKK cascade [Term] id: CCO:B0059244 name: GUC1B_HUMAN def: "Guanylyl cyclase-activating protein 2" [UniProtKB:Q9UMX6] synonym: "GCAP 2" EXACT [UniProtKB:Q9UMX6] synonym: "Guanylate cyclase activator 1B" EXACT [UniProtKB:Q9UMX6] xref: EMBL:AAD47279.1 xref: EMBL:CAB89166.1 xref: UniProtKB:Q9NU15 xref: UniProtKB:Q9UMX6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0012954 ! GUCA1B_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001692 ! calcium sensitive guanylate cyclase activator activity relationship: has_function CCO:F0004359 ! guanylate cyclase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000711 ! receptor guanylyl cyclase signaling pathway [Term] id: CCO:B0059245 name: DAPP1_HUMAN def: "Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide" [UniProtKB:Q9UN19] synonym: "B lymphocyte adapter protein Bam32" EXACT [UniProtKB:Q9UN19] synonym: "B-cell adapter molecule of 32 kDa" EXACT [UniProtKB:Q9UN19] synonym: "hDAPP1" EXACT [UniProtKB:Q9UN19] xref: EMBL:AAD49697.1 xref: EMBL:AAF14578.1 xref: EMBL:AAF29038.1 xref: EMBL:AAF44351.1 xref: EMBL:AAH12924.1 xref: EMBL:CAD28547.1 xref: UniProtKB:Q8TCK5 xref: UniProtKB:Q9UHF2 xref: UniProtKB:Q9UN19 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017523 ! DAPP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064631 ! DAPP1_HUMAN-Phosphotyrosine139 relationship: transforms_into CCO:B0064632 ! DAPP1_HUMAN-Phosphoserine141 [Term] id: CCO:B0059246 name: SCML1_HUMAN def: "Sex comb on midleg-like protein 1" [UniProtKB:Q9UN30] xref: EMBL:AAD47635.1 xref: EMBL:AAI05029.1 xref: EMBL:CAI42727.1 xref: UniProtKB:Q5H969 xref: UniProtKB:Q9UN30 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019848 ! SCML1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070349 ! SCML1_HUMAN-Phosphoserine17 [Term] id: CCO:B0059247 name: SOX13_HUMAN def: "SOX-13 protein" [UniProtKB:Q9UN79] synonym: "Islet cell antigen 12" EXACT [UniProtKB:Q9UN79] synonym: "Type 1 diabetes autoantigen ICA12" EXACT [UniProtKB:Q9UN79] xref: EMBL:AAC83687.1 xref: EMBL:AAD16237.1 xref: EMBL:AAD50120.1 xref: EMBL:AAF23875.1 xref: UniProtKB:O95275 xref: UniProtKB:O95826 xref: UniProtKB:Q9UHW7 xref: UniProtKB:Q9UN79 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019990 ! SOX13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070749 ! SOX13_HUMAN-Phosphoserine317 relationship: transforms_into CCO:B0070750 ! SOX13_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0070751 ! SOX13_HUMAN-Phosphoserine368 [Term] id: CCO:B0059248 name: RHG26_HUMAN def: "Rho GTPase-activating protein 26" [UniProtKB:Q9UNA1] synonym: "GTPase regulator associated with focal adhesion kinase" EXACT [UniProtKB:Q9UNA1] synonym: "Oligophrenin-1-like protein" EXACT [UniProtKB:Q9UNA1] synonym: "Rho-type GTPase-activating protein 26" EXACT [UniProtKB:Q9UNA1] xref: EMBL:AAD39482.1 xref: EMBL:BAA31596.1 xref: EMBL:CAA71414.2 xref: EMBL:CAC29145.2 xref: EMBL:CAC29146.2 xref: UniProtKB:O75117 xref: UniProtKB:Q9BYS6 xref: UniProtKB:Q9BYS7 xref: UniProtKB:Q9UJ00 xref: UniProtKB:Q9UNA1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019726 ! ARHGAP26_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059249 name: POLI_HUMAN def: "DNA polymerase iota" [UniProtKB:Q9UNA4] synonym: "EC 2.7.7.7" EXACT [UniProtKB:Q9UNA4] synonym: "Eta2" EXACT [UniProtKB:Q9UNA4] synonym: "RAD30 homolog B" EXACT [UniProtKB:Q9UNA4] xref: EMBL:AAD50381.1 xref: EMBL:AAF63383.1 xref: EMBL:AAH32662.1 xref: EMBL:AAM11872.1 xref: EMBL:CAB66605.1 xref: UniProtKB:Q8N590 xref: UniProtKB:Q9H0S1 xref: UniProtKB:Q9NYH6 xref: UniProtKB:Q9UNA4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019469 ! POLI_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0015013 ! dvl2-poli physical interaction relationship: participates_in CCO:I0015106 ! dazap2-poli physical interaction relationship: participates_in CCO:I0015436 ! ndp52-poli physical interaction relationship: participates_in CCO:P0000628 ! DNA replication [Term] id: CCO:B0059250 name: EDAR_HUMAN def: "Tumor necrosis factor receptor superfamily member EDAR precursor" [UniProtKB:Q9UNE0] synonym: "Anhidrotic ectodysplasin receptor 1" EXACT [UniProtKB:Q9UNE0] synonym: "Downless homolog" EXACT [UniProtKB:Q9UNE0] synonym: "Ectodermal dysplasia receptor" EXACT [UniProtKB:Q9UNE0] synonym: "Ectodysplasin-A receptor" EXACT [UniProtKB:Q9UNE0] synonym: "EDA-A1 receptor" EXACT [UniProtKB:Q9UNE0] xref: EMBL:AAD50076.1 xref: EMBL:AAD50077.1 xref: EMBL:AAH93870.1 xref: EMBL:AAH93872.1 xref: UniProtKB:Q52LL5 xref: UniProtKB:Q9UND9 xref: UniProtKB:Q9UNE0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017656 ! EDAR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001896 ! apical part of cell relationship: participates_in CCO:I0015932 ! edar-traf3 physical interaction relationship: participates_in CCO:I0015933 ! edar-nik physical interaction relationship: participates_in CCO:I0015934 ! edar-eda physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064919 ! EDAR_HUMAN-Phosphoserine324 [Term] id: CCO:B0059251 name: STUB1_HUMAN def: "STIP1 homology and U box-containing protein 1" [UniProtKB:Q9UNE7] synonym: "Antigen NY-CO-7" EXACT [UniProtKB:Q9UNE7] synonym: "Carboxy terminus of Hsp70-interacting protein" EXACT [UniProtKB:Q9UNE7] synonym: "CLL-associated antigen KW-8" EXACT [UniProtKB:Q9UNE7] synonym: "E3 ubiquitin-protein ligase CHIP" EXACT [UniProtKB:Q9UNE7] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9UNE7] xref: EMBL:AAC18038.1 xref: EMBL:AAD33400.1 xref: EMBL:AAG17211.1 xref: EMBL:AAH07545.1 xref: EMBL:AAH17178.1 xref: EMBL:AAH22788.1 xref: EMBL:AAH63617.1 xref: EMBL:AAK61242.1 xref: EMBL:AAL99927.1 xref: UniProtKB:O60526 xref: UniProtKB:Q969U2 xref: UniProtKB:Q9HBT1 xref: UniProtKB:Q9UNE7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020076 ! STUB1_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002521 ! Hsp90 protein inhibitor activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004344 ! Hsp70/Hsc70 protein inhibitor activity relationship: has_function CCO:F0004456 ! Hsp70 protein binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_function CCO:F0004601 ! TPR domain binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_function CCO:F0008202 ! Hsp90 protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001219 ! ubiquitin conjugating enzyme complex relationship: participates_in CCO:P0001282 ! ubiquitin-dependent SMAD protein catabolic process relationship: participates_in CCO:P0001432 ! positive regulation of protein ubiquitination relationship: participates_in CCO:P0001503 ! regulation of glucocorticoid metabolic process relationship: participates_in CCO:P0001617 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process relationship: transforms_into CCO:B0070980 ! STUB1_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0070981 ! STUB1_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0070982 ! STUB1_HUMAN-Phosphoserine273 relationship: transforms_into CCO:B0070983 ! STUB1_HUMAN-Phosphothreonine276 [Term] id: CCO:B0059252 name: Q9UNJ2_HUMAN xref: UniProtKB:Q9UNJ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000788 ! myosin complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059253 name: TF2AY_HUMAN def: "TFIIA-alpha and beta-like factor" [UniProtKB:Q9UNN4] synonym: "General transcription factor II A, 1-like factor" EXACT [UniProtKB:Q9UNN4] xref: EMBL:AAD39617.1 xref: EMBL:AAD39634.1 xref: EMBL:AAH25991.1 xref: UniProtKB:Q9UNN4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020237 ! GTF2A1L_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000276 ! transcription factor TFIIA complex relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059254 name: FAF1_HUMAN def: "FAS-associated factor 1" [UniProtKB:Q9UNN5] synonym: "hFAF1" EXACT [UniProtKB:Q9UNN5] synonym: "UBX domain-containing protein 12" EXACT [UniProtKB:Q9UNN5] synonym: "UBX domain-containing protein 3A" EXACT [UniProtKB:Q9UNN5] xref: EMBL:AAD27713.1 xref: EMBL:AAD51876.1 xref: EMBL:AAD51886.1 xref: EMBL:AAH04970.1 xref: EMBL:AAH67100.1 xref: EMBL:CAB63755.1 xref: EMBL:CAB67705.1 xref: UniProtKB:Q9UF34 xref: UniProtKB:Q9UNN5 xref: UniProtKB:Q9UNT3 xref: UniProtKB:Q9Y2Z3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017757 ! FAF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020245 ! ascc2-faf1 physical interaction relationship: participates_in CCO:P0000771 ! cytoplasmic sequestering of NF-kappaB relationship: participates_in CCO:P0001414 ! positive regulation of protein complex assembly relationship: participates_in CCO:P0002147 ! positive regulation of apoptosis relationship: transforms_into CCO:B0065192 ! FAF1_HUMAN-Phosphotyrosine225 relationship: transforms_into CCO:B0066114 ! FAF1_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0066115 ! FAF1_HUMAN-Phosphothreonine580 [Term] id: CCO:B0059255 name: PPIE_HUMAN def: "Peptidyl-prolyl cis-trans isomerase E" [UniProtKB:Q9UNP9] synonym: "Cyclophilin E" EXACT [UniProtKB:Q9UNP9] synonym: "Cyclophilin-33" EXACT [UniProtKB:Q9UNP9] synonym: "EC 5.2.1.8" EXACT [UniProtKB:Q9UNP9] synonym: "PPIase E" EXACT [UniProtKB:Q9UNP9] synonym: "Rotamase E" EXACT [UniProtKB:Q9UNP9] xref: EMBL:AAC00006.1 xref: EMBL:AAC00007.1 xref: EMBL:AAD19906.1 xref: EMBL:AAD19907.1 xref: EMBL:AAH04898.1 xref: EMBL:AAH08451.1 xref: EMBL:AAI07737.1 xref: EMBL:CAI19350.1 xref: EMBL:CAI19579.1 xref: UniProtKB:O43634 xref: UniProtKB:O43635 xref: UniProtKB:Q32Q72 xref: UniProtKB:Q5TGA0 xref: UniProtKB:Q9UIZ5 xref: UniProtKB:Q9UNP9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019481 ! PPIE_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003031 ! cyclosporin A binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0015630 ! ppie-xab2 physical interaction relationship: participates_in CCO:I0016277 ! ppie-mll-2 physical interaction relationship: participates_in CCO:I0018192 ! ppie-cyp33-1 physical interaction relationship: participates_in CCO:I0020402 ! phyhip-ppie physical interaction relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059256 name: TTF2_HUMAN def: "Transcription termination factor 2" [UniProtKB:Q9UNY4] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9UNY4] synonym: "F2" EXACT [UniProtKB:Q9UNY4] synonym: "Factor 2" EXACT [UniProtKB:Q9UNY4] synonym: "HuF2" EXACT [UniProtKB:Q9UNY4] synonym: "Lodestar homolog" EXACT [UniProtKB:Q9UNY4] synonym: "RNA polymerase II termination factor" EXACT [UniProtKB:Q9UNY4] synonym: "Transcription release factor 2" EXACT [UniProtKB:Q9UNY4] xref: EMBL:AAC64044.1 xref: EMBL:AAD49435.1 xref: EMBL:AAH30058.1 xref: EMBL:CAH71961.1 xref: EMBL:CAI12731.1 xref: EMBL:CAI12738.1 xref: UniProtKB:O75921 xref: UniProtKB:Q5T2K7 xref: UniProtKB:Q5VVU8 xref: UniProtKB:Q8N6I8 xref: UniProtKB:Q9UNY4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020379 ! TTF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071623 ! TTF2_HUMAN-Phosphoserine396 relationship: transforms_into CCO:B0071624 ! TTF2_HUMAN-Phosphoserine460 relationship: transforms_into CCO:B0071625 ! TTF2_HUMAN-Phosphoserine883 [Term] id: CCO:B0059257 name: ZN232_HUMAN def: "Zinc finger protein 232" [UniProtKB:Q9UNY5] synonym: "Zinc finger and SCAN domain-containing protein 11" EXACT [UniProtKB:Q9UNY5] xref: EMBL:AAD46135.1 xref: EMBL:AAH16039.2 xref: EMBL:CAB95963.1 xref: UniProtKB:Q9UNY5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020670 ! ZNF232_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015459 ! znf232-znf446 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059258 name: PA24C_HUMAN def: "Cytosolic phospholipase A2 gamma precursor" [UniProtKB:Q9UP65] synonym: "cPLA2-gamma" EXACT [UniProtKB:Q9UP65] synonym: "EC 3.1.1.4" EXACT [UniProtKB:Q9UP65] synonym: "Phospholipase A2 group IVC" EXACT [UniProtKB:Q9UP65] xref: EMBL:AAC32823.1 xref: EMBL:AAC78835.1 xref: EMBL:AAH63416.1 xref: EMBL:AAR25453.1 xref: EMBL:BAC87745.1 xref: EMBL:CAB43312.3 xref: UniProtKB:O75457 xref: UniProtKB:Q9UG68 xref: UniProtKB:Q9UP65 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019284 ! PLA2G4C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069041 ! PA24C_HUMAN-Phosphotyrosine530 relationship: transforms_into CCO:B0069042 ! PA24C_HUMAN-Cysteine methyl ester538 [Term] id: CCO:B0059259 name: GPR34_HUMAN def: "Probable G-protein coupled receptor 34" [UniProtKB:Q9UPC5] xref: EMBL:AAD17248.1 xref: EMBL:AAD50531.1 xref: EMBL:AAH20678.1 xref: EMBL:BAB55362.1 xref: UniProtKB:O95853 xref: UniProtKB:Q9UPC5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018017 ! GPR34_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059260 name: Q9UPH3_HUMAN xref: UniProtKB:Q9UPH3 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059261 name: LHX61_HUMAN def: "LIM/homeobox protein Lhx6.1" [UniProtKB:Q9UPM6] synonym: "Lhx6" EXACT [UniProtKB:Q9UPM6] synonym: "LIM homeobox protein 6.1" EXACT [UniProtKB:Q9UPM6] xref: EMBL:AAI03938.1 xref: EMBL:BAA83422.1 xref: EMBL:BAA83423.1 xref: EMBL:CAB66505.1 xref: EMBL:CAI14703.1 xref: UniProtKB:Q5T7S8 xref: UniProtKB:Q9NTK3 xref: UniProtKB:Q9UPM5 xref: UniProtKB:Q9UPM6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018489 ! LHX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059262 name: IQEC3_HUMAN def: "IQ motif and SEC7 domain-containing protein 3" [UniProtKB:Q9UPP2] xref: EMBL:AAH24764.1 xref: EMBL:BAA83062.1 xref: UniProtKB:A6NKV9 xref: UniProtKB:Q8TB43 xref: UniProtKB:Q9UPP2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018307 ! IQSEC3_human relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0001526 ! regulation of ARF protein signal transduction relationship: transforms_into CCO:B0067146 ! IQEC3_HUMAN-Phosphothreonine649 relationship: transforms_into CCO:B0067147 ! IQEC3_HUMAN-Phosphoserine1019 [Term] id: CCO:B0059263 name: CENG2_HUMAN def: "Centaurin-gamma-2" [UniProtKB:Q9UPQ3] synonym: "AGAP-1" EXACT [UniProtKB:Q9UPQ3] synonym: "ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1" EXACT [UniProtKB:Q9UPQ3] synonym: "GGAP1" EXACT [UniProtKB:Q9UPQ3] synonym: "GTP-binding and GTPase-activating protein 1" EXACT [UniProtKB:Q9UPQ3] xref: EMBL:AAH60814.1 xref: EMBL:AAK56506.1 xref: EMBL:AAL04172.1 xref: EMBL:BAA83051.2 xref: EMBL:BAA91862.1 xref: UniProtKB:Q541S5 xref: UniProtKB:Q6P9D7 xref: UniProtKB:Q9NV93 xref: UniProtKB:Q9UPQ3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0008587 ! CENTG2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001583 ! regulation of ARF GTPase activity relationship: transforms_into CCO:B0064270 ! CENG2_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0064271 ! CENG2_HUMAN-Phosphothreonine836 [Term] id: CCO:B0059264 name: TRI35_HUMAN def: "Tripartite motif-containing protein 35" [UniProtKB:Q9UPQ4] synonym: "Hemopoietic lineage switch protein 5" EXACT [UniProtKB:Q9UPQ4] xref: EMBL:AAH18337.1 xref: EMBL:AAH69226.1 xref: EMBL:AAO85480.1 xref: EMBL:BAA83050.1 xref: UniProtKB:Q86XQ0 xref: UniProtKB:Q8WVA4 xref: UniProtKB:Q9UPQ4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020355 ! TRIM35_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:B0059265 name: PLCL2_HUMAN def: "Inactive phospholipase C-like protein 2" [UniProtKB:Q9UPR0] synonym: "Phospholipase C epsilon 2" EXACT [UniProtKB:Q9UPR0] synonym: "Phospholipase C-L2" EXACT [UniProtKB:Q9UPR0] synonym: "PLC-L(2)" EXACT [UniProtKB:Q9UPR0] synonym: "PLC-L2" EXACT [UniProtKB:Q9UPR0] xref: EMBL:AAH36392.1 xref: EMBL:BAA83044.1 xref: EMBL:BAB14606.1 xref: EMBL:CAB55974.1 xref: UniProtKB:Q8N498 xref: UniProtKB:Q9H8L0 xref: UniProtKB:Q9UFP9 xref: UniProtKB:Q9UPR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019438 ! PLCL2_human relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069402 ! PLCL2_HUMAN-Phosphothreonine584 relationship: transforms_into CCO:B0069403 ! PLCL2_HUMAN-Phosphoserine1113 [Term] id: CCO:B0059266 name: SMG5_HUMAN def: "Protein SMG5" [UniProtKB:Q9UPR3] synonym: "EST1-like protein B" EXACT [UniProtKB:Q9UPR3] synonym: "LPTS-interacting protein" EXACT [UniProtKB:Q9UPR3] synonym: "LPTS-RP1" EXACT [UniProtKB:Q9UPR3] synonym: "SMG-5 homolog" EXACT [UniProtKB:Q9UPR3] xref: EMBL:AAH07453.2 xref: EMBL:AAH38296.1 xref: EMBL:AAO17582.1 xref: EMBL:AAQ84301.1 xref: EMBL:BAA83041.2 xref: EMBL:BAC53623.1 xref: EMBL:CAH56374.1 xref: EMBL:CAI14160.1 xref: EMBL:CAI15525.1 xref: UniProtKB:Q5QJE7 xref: UniProtKB:Q659C7 xref: UniProtKB:Q8IXC0 xref: UniProtKB:Q8IY09 xref: UniProtKB:Q96IJ7 xref: UniProtKB:Q9UPR3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019951 ! SMG5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008162 ! protein phosphatase 2A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002016 ! regulation of dephosphorylation [Term] id: CCO:B0059267 name: ZN409_HUMAN def: "Zinc finger protein 409" [UniProtKB:Q9UPU6] xref: EMBL:BAA83008.2 xref: UniProtKB:Q9UPU6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020735 ! ZNF409_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059268 name: TBD2B_HUMAN def: "TBC1 domain family member 2B" [UniProtKB:Q9UPU7] xref: EMBL:AAH33712.1 xref: EMBL:AAI52466.1 xref: EMBL:BAA83007.1 xref: EMBL:BAA90990.1 xref: EMBL:EAW99188.1 xref: EMBL:EAW99190.1 xref: UniProtKB:A7MD42 xref: UniProtKB:Q8N1F9 xref: UniProtKB:Q9NXM0 xref: UniProtKB:Q9UPU7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020187 ! TBC1D2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity relationship: transforms_into CCO:B0071240 ! TBD2B_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0071241 ! TBD2B_HUMAN-Phosphoserine511 relationship: transforms_into CCO:B0071242 ! TBD2B_HUMAN-Phosphoserine949 relationship: transforms_into CCO:B0071243 ! TBD2B_HUMAN-Phosphoserine957 [Term] id: CCO:B0059269 name: TRAK1_HUMAN def: "Trafficking kinesin-binding protein 1" [UniProtKB:Q9UPV9] synonym: "106 kDa O-GlcNAc transferase-interacting protein" EXACT [UniProtKB:Q9UPV9] xref: EMBL:AAH15922.1 xref: EMBL:BAA82994.2 xref: UniProtKB:Q96B69 xref: UniProtKB:Q9UPV9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020345 ! TRAK1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004207 ! kinesin-associated mitochondrial adaptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0059270 name: SATB2_HUMAN def: "DNA-binding protein SATB2" [UniProtKB:Q9UPW6] synonym: "Special AT-rich sequence-binding protein 2" EXACT [UniProtKB:Q9UPW6] xref: EMBL:AAH98136.1 xref: EMBL:AAH99723.1 xref: EMBL:AAI03501.1 xref: EMBL:BAA82986.1 xref: UniProtKB:Q4V763 xref: UniProtKB:Q9UPW6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019840 ! SATB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070322 ! SATB2_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0070323 ! SATB2_HUMAN-Phosphoserine446 relationship: transforms_into CCO:B0070324 ! SATB2_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0070325 ! SATB2_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0070326 ! SATB2_HUMAN-Phosphoserine452 [Term] id: CCO:B0059271 name: UN13A_HUMAN def: "Protein unc-13 homolog A" [UniProtKB:Q9UPW8] synonym: "Munc13-1" EXACT [UniProtKB:Q9UPW8] xref: EMBL:BAA82984.2 xref: UniProtKB:Q9UPW8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020407 ! UNC13A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017291 ! epb41l3-kiaa1032 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0071732 ! UN13A_HUMAN-Phosphoserine245 [Term] id: CCO:B0059272 name: SHAN2_HUMAN def: "SH3 and multiple ankyrin repeat domains protein 2" [UniProtKB:Q9UPX8] synonym: "Cortactin-binding protein 1" EXACT [UniProtKB:Q9UPX8] synonym: "CortBP1" EXACT [UniProtKB:Q9UPX8] synonym: "Shank2" EXACT [UniProtKB:Q9UPX8] xref: EMBL:AAF02496.1 xref: EMBL:AAH93885.1 xref: EMBL:AAI12098.1 xref: EMBL:AAZ77790.1 xref: EMBL:BAA82974.1 xref: UniProtKB:Q3Y8G9 xref: UniProtKB:Q52LK2 xref: UniProtKB:Q9UKP1 xref: UniProtKB:Q9UPX8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019890 ! SHANK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0070475 ! SHAN2_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0070476 ! SHAN2_HUMAN-Phosphothreonine509 relationship: transforms_into CCO:B0070477 ! SHAN2_HUMAN-Phosphothreonine682 relationship: transforms_into CCO:B0070478 ! SHAN2_HUMAN-Phosphoserine1052 relationship: transforms_into CCO:B0070479 ! SHAN2_HUMAN-Phosphoserine1113 relationship: transforms_into CCO:B0070480 ! SHAN2_HUMAN-Phosphoserine1117 relationship: transforms_into CCO:B0070481 ! SHAN2_HUMAN-Phosphothreonine1119 [Term] id: CCO:B0059273 name: KCNH4_HUMAN def: "Potassium voltage-gated channel subfamily H member 4" [UniProtKB:Q9UQ05] synonym: "BEC2" EXACT [UniProtKB:Q9UQ05] synonym: "Brain-specific eag-like channel 2" EXACT [UniProtKB:Q9UQ05] synonym: "ELK channel 1" EXACT [UniProtKB:Q9UQ05] synonym: "ELK1" EXACT [UniProtKB:Q9UQ05] synonym: "Ether-a-go-go-like potassium channel 1" EXACT [UniProtKB:Q9UQ05] synonym: "Voltage-gated potassium channel subunit Kv12.3" EXACT [UniProtKB:Q9UQ05] xref: EMBL:BAA83592.1 xref: UniProtKB:Q9UQ05 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018393 ! KCNH4_human relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000401 ! two-component signal transduction system (phosphorelay) relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059274 name: MOK_HUMAN def: "MAPK/MAK/MRK overlapping kinase" [UniProtKB:Q9UQ07] synonym: "EC 2.7.11.22" EXACT [UniProtKB:Q9UQ07] synonym: "MOK protein kinase" EXACT [UniProtKB:Q9UQ07] synonym: "RAGE-1" EXACT [UniProtKB:Q9UQ07] synonym: "Renal tumor antigen 1" EXACT [UniProtKB:Q9UQ07] xref: EMBL:AAB38079.1 xref: EMBL:AAB38082.1 xref: EMBL:AAB38085.1 xref: EMBL:AAB38087.1 xref: EMBL:AAH53536.1 xref: EMBL:BAA81688.1 xref: UniProtKB:Q92790 xref: UniProtKB:Q93067 xref: UniProtKB:Q9UQ07 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018643 ! RAGE_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059275 name: Q9UQ19_HUMAN xref: UniProtKB:Q9UQ19 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059276 name: CNTN6_HUMAN def: "Contactin-6 precursor" [UniProtKB:Q9UQ52] synonym: "hNB-3" EXACT [UniProtKB:Q9UQ52] synonym: "Neural recognition molecule NB-3" EXACT [UniProtKB:Q9UQ52] xref: EMBL:AAI13119.1 xref: EMBL:BAA82612.1 xref: UniProtKB:Q2KHM2 xref: UniProtKB:Q9UQ52 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017416 ! CNTN6_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:B0059277 name: CTND2_HUMAN def: "Catenin delta-2" [UniProtKB:Q9UQB3] synonym: "Delta-catenin" EXACT [UniProtKB:Q9UQB3] synonym: "GT24" EXACT [UniProtKB:Q9UQB3] synonym: "Neural plakophilin-related ARM-repeat protein" EXACT [UniProtKB:Q9UQB3] synonym: "Neurojungin" EXACT [UniProtKB:Q9UQB3] synonym: "NPRAP" EXACT [UniProtKB:Q9UQB3] xref: EMBL:AAB68599.1 xref: EMBL:AAB83940.1 xref: EMBL:AAB88185.1 xref: EMBL:AAB96357.1 xref: EMBL:AAB97957.1 xref: EMBL:AAC63103.1 xref: EMBL:AAD00453.1 xref: EMBL:BAA36163.1 xref: UniProtKB:O00379 xref: UniProtKB:O15390 xref: UniProtKB:O43206 xref: UniProtKB:O43840 xref: UniProtKB:Q13589 xref: UniProtKB:Q9UM66 xref: UniProtKB:Q9UPM3 xref: UniProtKB:Q9UQB3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017492 ! CTNND2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0064576 ! CTND2_HUMAN-Phosphoserine32 relationship: transforms_into CCO:B0064577 ! CTND2_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0064578 ! CTND2_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0064579 ! CTND2_HUMAN-Phosphoserine415 relationship: transforms_into CCO:B0064580 ! CTND2_HUMAN-Phosphoserine474 relationship: transforms_into CCO:B0064581 ! CTND2_HUMAN-Phosphotyrosine516 relationship: transforms_into CCO:B0064582 ! CTND2_HUMAN-Phosphoserine534 relationship: transforms_into CCO:B0064583 ! CTND2_HUMAN-Phosphoserine537 relationship: transforms_into CCO:B0064584 ! CTND2_HUMAN-Phosphoserine1072 relationship: transforms_into CCO:B0064585 ! CTND2_HUMAN-Phosphoserine1076 relationship: transforms_into CCO:B0064586 ! CTND2_HUMAN-Phosphoserine1127 [Term] id: CCO:B0059278 name: BAIP2_HUMAN def: "Brain-specific angiogenesis inhibitor 1-associated protein 2" [UniProtKB:Q9UQB8] synonym: "BAI-associated protein 2" EXACT [UniProtKB:Q9UQB8] synonym: "BAI1-associated protein 2" EXACT [UniProtKB:Q9UQB8] synonym: "Fas ligand-associated factor 3" EXACT [UniProtKB:Q9UQB8] synonym: "FLAF3" EXACT [UniProtKB:Q9UQB8] synonym: "Insulin receptor substrate p53" EXACT [UniProtKB:Q9UQB8] synonym: "Insulin receptor substrate p53/p58" EXACT [UniProtKB:Q9UQB8] synonym: "Insulin receptor substrate protein of 53 kDa" EXACT [UniProtKB:Q9UQB8] synonym: "IRS-58" EXACT [UniProtKB:Q9UQB8] synonym: "IRSp53" EXACT [UniProtKB:Q9UQB8] synonym: "IRSp53/58" EXACT [UniProtKB:Q9UQB8] synonym: "Protein BAP2" EXACT [UniProtKB:Q9UQB8] xref: EMBL:AAB93497.1 xref: EMBL:AAH14020.1 xref: EMBL:AAH32559.1 xref: EMBL:BAA36586.1 xref: EMBL:BAA36587.1 xref: EMBL:BAA74773.1 xref: EMBL:BAA74774.1 xref: EMBL:BAC57945.1 xref: EMBL:BAC57946.1 xref: EMBL:BAC57947.1 xref: EMBL:BAC57948.1 xref: EMBL:BAD96390.1 xref: UniProtKB:O43858 xref: UniProtKB:Q53HB1 xref: UniProtKB:Q86WC1 xref: UniProtKB:Q8N5C0 xref: UniProtKB:Q96CR7 xref: UniProtKB:Q9UBR3 xref: UniProtKB:Q9UQ43 xref: UniProtKB:Q9UQB8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017122 ! BAIAP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015162 ! baiap2-nckipsd physical interaction relationship: participates_in CCO:I0015834 ! baiap2-eps8 physical interaction relationship: participates_in CCO:I0017548 ! baiap2-atn1 physical interaction relationship: participates_in CCO:I0018443 ! pbx2-irsp53 physical interaction relationship: participates_in CCO:I0020255 ! baiap2-c14orf1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000818 ! insulin receptor signaling pathway relationship: transforms_into CCO:B0063710 ! BAIP2_HUMAN-Phosphotyrosine157 relationship: transforms_into CCO:B0063711 ! BAIP2_HUMAN-Phosphothreonine296 relationship: transforms_into CCO:B0063712 ! BAIP2_HUMAN-Phosphotyrosine310 relationship: transforms_into CCO:B0063713 ! BAIP2_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0063714 ! BAIP2_HUMAN-Phosphoserine325 relationship: transforms_into CCO:B0063715 ! BAIP2_HUMAN-Phosphotyrosine337 relationship: transforms_into CCO:B0063716 ! BAIP2_HUMAN-Phosphoserine346 relationship: transforms_into CCO:B0063717 ! BAIP2_HUMAN-Phosphothreonine348 relationship: transforms_into CCO:B0063718 ! BAIP2_HUMAN-Phosphoserine366 relationship: transforms_into CCO:B0063719 ! BAIP2_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0063720 ! BAIP2_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0063721 ! BAIP2_HUMAN-Phosphoserine454 relationship: transforms_into CCO:B0063722 ! BAIP2_HUMAN-Phosphotyrosine491 relationship: transforms_into CCO:B0063723 ! BAIP2_HUMAN-Phosphotyrosine505 [Term] id: CCO:B0059279 name: Q9UQD2_HUMAN def: "R31665_2 [AA 1-673 ] (Zinc finger protein 28 homolog (Mouse), isoform CRA_b)" [UniProtKB:Q9UQD2] xref: EMBL:AAD23606.1 xref: EMBL:EAW72464.1 xref: UniProtKB:Q9UQD2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020587 ! ZFP28_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059280 name: JIP1_HUMAN def: "C-jun-amino-terminal kinase-interacting protein 1" [UniProtKB:Q9UQF2] synonym: "IB-1" EXACT [UniProtKB:Q9UQF2] synonym: "Islet-brain 1" EXACT [UniProtKB:Q9UQF2] synonym: "JIP-1" EXACT [UniProtKB:Q9UQF2] synonym: "JNK MAP kinase scaffold protein 1" EXACT [UniProtKB:Q9UQF2] synonym: "JNK-interacting protein 1" EXACT [UniProtKB:Q9UQF2] synonym: "Mitogen-activated protein kinase 8-interacting protein 1" EXACT [UniProtKB:Q9UQF2] xref: EMBL:AAC19150.1 xref: EMBL:AAD20443.1 xref: UniProtKB:O43407 xref: UniProtKB:Q9UQF2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018365 ! MAPK8IP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018208 ! mapk8ip1-app-2 physical interaction relationship: participates_in CCO:I0018526 ! mapk8ip1-app-4 direct interaction relationship: participates_in CCO:I0018573 ! mapk8ip1-app-1 physical interaction relationship: participates_in CCO:I0018855 ! mapk8ip1-app-3 physical interaction relationship: participates_in CCO:I0020434 ! recql5-mapk8ip1 physical interaction relationship: participates_in CCO:P0002689 ! regulation of JNK cascade relationship: transforms_into CCO:B0067219 ! JIP1_HUMAN-Phosphothreonine103 relationship: transforms_into CCO:B0067220 ! JIP1_HUMAN-Phosphothreonine205 [Term] id: CCO:B0059281 name: POK20_HUMAN def: "HERV-K_3q27.3 provirus ancestral Pol protein" [UniProtKB:Q9UQG0] xref: EMBL:AAC63290.1 xref: EMBL:AAC63292.1 xref: EMBL:AAO27434.1 xref: UniProtKB:Q6KH06 xref: UniProtKB:Q86YP3 xref: UniProtKB:Q9UQG0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0059282 name: TENN_HUMAN def: "Tenascin-N precursor" [UniProtKB:Q9UQP3] synonym: "TN-N" EXACT [UniProtKB:Q9UQP3] xref: EMBL:CAB41260.1 xref: EMBL:CAI19286.1 xref: EMBL:CAI19966.1 xref: UniProtKB:Q5R360 xref: UniProtKB:Q9UQP3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020231 ! TNN_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000709 ! cell surface relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059283 name: SH2B3_HUMAN def: "SH2B adapter protein 3" [UniProtKB:Q9UQQ2] synonym: "Lymphocyte adapter protein" EXACT [UniProtKB:Q9UQQ2] synonym: "Lymphocyte-specific adapter protein Lnk" EXACT [UniProtKB:Q9UQQ2] synonym: "Signal transduction protein Lnk" EXACT [UniProtKB:Q9UQQ2] xref: EMBL:AAC71695.1 xref: EMBL:CAB42642.1 xref: UniProtKB:O95184 xref: UniProtKB:Q9UQQ2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019888 ! SH2B3_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059284 name: SCML2_HUMAN def: "Sex comb on midleg-like protein 2" [UniProtKB:Q9UQR0] xref: EMBL:AAH51913.1 xref: EMBL:AAH64617.1 xref: EMBL:CAB38943.1 xref: EMBL:CAD38792.1 xref: UniProtKB:Q86U98 xref: UniProtKB:Q8IWD0 xref: UniProtKB:Q8NDP2 xref: UniProtKB:Q9UGC5 xref: UniProtKB:Q9UQR0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019849 ! SCML2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0070350 ! SCML2_HUMAN-Phosphoserine256 relationship: transforms_into CCO:B0070351 ! SCML2_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0070352 ! SCML2_HUMAN-Phosphoserine267 relationship: transforms_into CCO:B0070353 ! SCML2_HUMAN-Phosphoserine299 relationship: transforms_into CCO:B0070354 ! SCML2_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0070355 ! SCML2_HUMAN-Phosphothreonine305 relationship: transforms_into CCO:B0070356 ! SCML2_HUMAN-Phosphoserine499 relationship: transforms_into CCO:B0070357 ! SCML2_HUMAN-Phosphothreonine503 relationship: transforms_into CCO:B0070358 ! SCML2_HUMAN-Phosphoserine511 relationship: transforms_into CCO:B0070359 ! SCML2_HUMAN-Phosphoserine570 relationship: transforms_into CCO:B0070360 ! SCML2_HUMAN-Phosphoserine576 relationship: transforms_into CCO:B0070361 ! SCML2_HUMAN-Phosphoserine583 relationship: transforms_into CCO:B0070362 ! SCML2_HUMAN-Phosphoserine590 relationship: transforms_into CCO:B0070363 ! SCML2_HUMAN-Phosphoserine594 [Term] id: CCO:B0059285 name: ZN148_HUMAN def: "Zinc finger protein 148" [UniProtKB:Q9UQR1] synonym: "Transcription factor ZBP-89" EXACT [UniProtKB:Q9UQR1] synonym: "Zinc finger DNA-binding protein 89" EXACT [UniProtKB:Q9UQR1] xref: EMBL:AAB57692.1 xref: EMBL:AAC39926.1 xref: EMBL:AAH50260.1 xref: EMBL:CAA15422.1 xref: UniProtKB:O00389 xref: UniProtKB:O43591 xref: UniProtKB:Q58EY5 xref: UniProtKB:Q9UQR1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020632 ! ZNF148_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072050 ! ZN148_HUMAN-Phosphothreonine194 relationship: transforms_into CCO:B0072051 ! ZN148_HUMAN-Phosphoserine250 relationship: transforms_into CCO:B0072052 ! ZN148_HUMAN-Phosphothreonine305 relationship: transforms_into CCO:B0072053 ! ZN148_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0072054 ! ZN148_HUMAN-Phosphoserine412 relationship: transforms_into CCO:B0072055 ! ZN148_HUMAN-Phosphoserine784 [Term] id: CCO:B0059286 name: LAMP3_HUMAN def: "Lysosome-associated membrane glycoprotein 3 precursor" [UniProtKB:Q9UQV4] synonym: "CD208 antigen" EXACT [UniProtKB:Q9UQV4] synonym: "DC LAMP" EXACT [UniProtKB:Q9UQV4] synonym: "DC-lysosome-associated membrane glycoprotein" EXACT [UniProtKB:Q9UQV4] synonym: "LAMP-3" EXACT [UniProtKB:Q9UQV4] synonym: "Lysosomal-associated membrane protein 3" EXACT [UniProtKB:Q9UQV4] synonym: "Protein TSC403" EXACT [UniProtKB:Q9UQV4] xref: EMBL:AAH32940.1 xref: EMBL:BAA34533.1 xref: EMBL:CAA06691.1 xref: UniProtKB:O94781 xref: UniProtKB:Q8NEC8 xref: UniProtKB:Q9UQV4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018455 ! LAMP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059287 name: POK3_HUMAN def: "HERV-K_19q12 provirus ancestral Pol protein" [UniProtKB:Q9WJR5] synonym: "HERV-K(C19) Pol protein" EXACT [UniProtKB:Q9WJR5] xref: EMBL:AAB63115.1 xref: EMBL:CAA76882.1 xref: UniProtKB:O15312 xref: UniProtKB:Q9WJR5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019468 ! ERVK6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000920 ! ribonuclease H activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002244 ! integrase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000641 ! RNA-dependent DNA replication [Term] id: CCO:B0059288 name: Q9Y220_HUMAN xref: UniProtKB:Q9Y220 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059289 name: PDE10_HUMAN def: "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A" [UniProtKB:Q9Y233] synonym: "EC 3.1.4.17" EXACT [UniProtKB:Q9Y233] xref: EMBL:AAD32595.1 xref: EMBL:AAD32596.1 xref: EMBL:AAI04859.1 xref: EMBL:AAI04861.1 xref: EMBL:BAA78034.1 xref: EMBL:CAB92797.2 xref: EMBL:CAH72023.1 xref: EMBL:CAI20436.1 xref: UniProtKB:Q9NTV4 xref: UniProtKB:Q9Y233 xref: UniProtKB:Q9Y5T1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019330 ! PDE10A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020687 ! wdr3-pde10a physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059290 name: NOD1_HUMAN def: "Nucleotide-binding oligomerization domain-containing protein 1" [UniProtKB:Q9Y239] synonym: "Caspase recruitment domain-containing protein 4" EXACT [UniProtKB:Q9Y239] xref: EMBL:AAD28350.1 xref: EMBL:AAD29125.1 xref: EMBL:AAD43922.1 xref: EMBL:AAH40339.1 xref: EMBL:AAS46897.1 xref: UniProtKB:Q549U4 xref: UniProtKB:Q8IWF5 xref: UniProtKB:Q9Y239 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018815 ! NOD1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0005721 ! peptidoglycan binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0059291 name: CLC11_HUMAN def: "C-type lectin domain family 11 member A precursor" [UniProtKB:Q9Y240] synonym: "C-type lectin superfamily member 3" EXACT [UniProtKB:Q9Y240] synonym: "Lymphocyte secreted C-type lectin" EXACT [UniProtKB:Q9Y240] synonym: "p47" EXACT [UniProtKB:Q9Y240] synonym: "Stem cell growth factor" EXACT [UniProtKB:Q9Y240] xref: EMBL:AAC39569.1 xref: EMBL:AAD26533.1 xref: EMBL:AAH05810.1 xref: EMBL:BAA32404.1 xref: UniProtKB:Q9Y240 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017374 ! CLEC11A_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation [Term] id: CCO:B0059292 name: CCL26_HUMAN def: "C-C motif chemokine 26 precursor" [UniProtKB:Q9Y258] synonym: "CC chemokine IMAC" EXACT [UniProtKB:Q9Y258] synonym: "Eotaxin-3" EXACT [UniProtKB:Q9Y258] synonym: "Macrophage inflammatory protein 4-alpha" EXACT [UniProtKB:Q9Y258] synonym: "MIP-4-alpha" EXACT [UniProtKB:Q9Y258] synonym: "Small-inducible cytokine A26" EXACT [UniProtKB:Q9Y258] synonym: "Thymic stroma chemokine-1" EXACT [UniProtKB:Q9Y258] synonym: "TSC-1" EXACT [UniProtKB:Q9Y258] xref: EMBL:AAD15411.1 xref: EMBL:AAD22197.1 xref: EMBL:AAD46495.1 xref: EMBL:AAF09265.1 xref: EMBL:AAH69394.1 xref: EMBL:AAH93773.1 xref: EMBL:AAI01666.1 xref: EMBL:AAQ89252.1 xref: EMBL:BAA36704.1 xref: EMBL:BAA84579.1 xref: UniProtKB:Q52LV8 xref: UniProtKB:Q9Y258 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017271 ! CCL26_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001674 ! chemokine activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059293 name: PLAP_HUMAN def: "Phospholipase A-2-activating protein" [UniProtKB:Q9Y263] synonym: "PLA2P" EXACT [UniProtKB:Q9Y263] synonym: "PLAP" EXACT [UniProtKB:Q9Y263] xref: EMBL:AAD03030.1 xref: EMBL:AAD42075.1 xref: EMBL:AAH32551.1 xref: EMBL:BAA91803.1 xref: EMBL:BAA92105.1 xref: EMBL:BAD97264.1 xref: EMBL:CAB42881.1 xref: EMBL:CAB63739.1 xref: EMBL:CAH72641.1 xref: UniProtKB:Q53EU5 xref: UniProtKB:Q5VY33 xref: UniProtKB:Q9NUL8 xref: UniProtKB:Q9NVE9 xref: UniProtKB:Q9UF53 xref: UniProtKB:Q9Y263 xref: UniProtKB:Q9Y5L1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019427 ! PLAA_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003029 ! phospholipase A2 activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059294 name: ANGP4_HUMAN def: "Angiopoietin-4 precursor" [UniProtKB:Q9Y264] synonym: "ANG-3" EXACT [UniProtKB:Q9Y264] synonym: "ANG-4" EXACT [UniProtKB:Q9Y264] xref: EMBL:AAD21587.1 xref: EMBL:AAD31728.1 xref: EMBL:AAI11977.1 xref: EMBL:AAI11979.1 xref: EMBL:CAC09933.2 xref: EMBL:CAI22922.1 xref: UniProtKB:Q5TFF4 xref: UniProtKB:Q9H4Z4 xref: UniProtKB:Q9Y264 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016974 ! ANGPT4_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0004384 ! transmembrane receptor protein tyrosine kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059295 name: RASD1_HUMAN def: "Dexamethasone-induced Ras-related protein 1 precursor" [UniProtKB:Q9Y272] synonym: "Activator of G-protein signaling 1" EXACT [UniProtKB:Q9Y272] xref: EMBL:AAD34206.1 xref: EMBL:AAD34621.1 xref: EMBL:AAF01364.1 xref: EMBL:AAF72997.1 xref: EMBL:AAG44256.1 xref: EMBL:AAH18041.1 xref: EMBL:AAM21071.1 xref: UniProtKB:Q9NYB4 xref: UniProtKB:Q9Y272 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019624 ! RASD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014982 ! plscr1-rasd1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0069749 ! RASD1_HUMAN-S-nitrosocysteine11 relationship: transforms_into CCO:B0069750 ! RASD1_HUMAN-Cysteine methyl ester278 [Term] id: CCO:B0059296 name: TN13B_HUMAN def: "Tumor necrosis factor ligand superfamily member 13B" [UniProtKB:Q9Y275] synonym: "B cell-activating factor" EXACT [UniProtKB:Q9Y275] synonym: "B lymphocyte stimulator" EXACT [UniProtKB:Q9Y275] synonym: "BAFF" EXACT [UniProtKB:Q9Y275] synonym: "BLyS" EXACT [UniProtKB:Q9Y275] synonym: "CD257 antigen" EXACT [UniProtKB:Q9Y275] synonym: "Dendritic cell-derived TNF-like molecule" EXACT [UniProtKB:Q9Y275] synonym: "TALL-1" EXACT [UniProtKB:Q9Y275] synonym: "TNF- and APOL-related leukocyte expressed ligand 1" EXACT [UniProtKB:Q9Y275] xref: EMBL:AAD21092.1 xref: EMBL:AAD25356.1 xref: EMBL:AAD29421.1 xref: EMBL:AAF01432.1 xref: EMBL:AAF60219.1 xref: EMBL:AAH20674.1 xref: EMBL:AAQ89240.1 xref: EMBL:BAB90856.1 xref: UniProtKB:Q9Y275 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020294 ! TNFSF13B_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001465 ! tumor necrosis factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017363 ! tac1-blys-3 physical interaction relationship: participates_in CCO:I0017365 ! tac1-ztnf4 physical interaction relationship: participates_in CCO:I0017366 ! bcma-ztnf4-1 physical interaction relationship: participates_in CCO:I0017502 ! tac1-tall_1 physical interaction relationship: participates_in CCO:I0017503 ! tac1-tall_1-1 physical interaction relationship: participates_in CCO:I0017869 ! tac1-blys-2 physical interaction relationship: participates_in CCO:I0018020 ! tac1-blys-4 direct interaction relationship: participates_in CCO:I0018492 ! tac1-blys physical interaction relationship: participates_in CCO:I0019359 ! tac1-blys-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000815 ! cell proliferation relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0001353 ! positive regulation of B cell proliferation relationship: participates_in CCO:P0001401 ! T cell costimulation relationship: participates_in CCO:P0001402 ! B cell costimulation relationship: participates_in CCO:P0002041 ! positive regulation of T cell proliferation relationship: participates_in CCO:P0002592 ! positive regulation of survival gene product expression [Term] id: CCO:B0059297 name: VSIG4_HUMAN def: "V-set and immunoglobulin domain-containing protein 4 precursor" [UniProtKB:Q9Y279] synonym: "Protein Z39Ig" EXACT [UniProtKB:Q9Y279] xref: EMBL:AAH10525.1 xref: EMBL:AAQ88707.1 xref: EMBL:CAB51536.1 xref: UniProtKB:Q6UXI4 xref: UniProtKB:Q9Y279 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020464 ! VSIG4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002047 ! negative regulation of T cell proliferation [Term] id: CCO:B0059298 name: INVS_HUMAN def: "Inversin" [UniProtKB:Q9Y283] synonym: "Inversion of embryo turning homolog" EXACT [UniProtKB:Q9Y283] synonym: "Nephrocystin-2" EXACT [UniProtKB:Q9Y283] xref: EMBL:AAC79436.1 xref: EMBL:AAC79456.1 xref: EMBL:AAC79457.1 xref: EMBL:AAD02131.2 xref: EMBL:AAH06370.1 xref: EMBL:AAH41665.1 xref: EMBL:CAH72173.1 xref: EMBL:CAH72174.1 xref: EMBL:CAI39744.1 xref: EMBL:CAI40807.1 xref: UniProtKB:Q5W0T6 xref: UniProtKB:Q8IVX8 xref: UniProtKB:Q9BRB9 xref: UniProtKB:Q9Y283 xref: UniProtKB:Q9Y488 xref: UniProtKB:Q9Y498 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018296 ! INVS_human relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015728 ! hif1an-invs physical interaction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0059299 name: T53G5_HUMAN def: "TP53-target gene 5 protein" [UniProtKB:Q9Y2B4] synonym: "TP53-inducible gene 5 protein" EXACT [UniProtKB:Q9Y2B4] xref: EMBL:AAH36785.1 xref: EMBL:BAA76405.1 xref: EMBL:CAC18107.1 xref: UniProtKB:Q9Y2B4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020112 ! TP53TG5_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:B0059300 name: ZN652_HUMAN def: "Zinc finger protein 652" [UniProtKB:Q9Y2D9] xref: EMBL:BAA76768.2 xref: EMBL:CAI45974.1 xref: UniProtKB:Q5H9Q0 xref: UniProtKB:Q9Y2D9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020875 ! ZNF652_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017804 ! cbfa2t2-znf652-3 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072206 ! ZN652_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0072207 ! ZN652_HUMAN-Phosphoserine380 [Term] id: CCO:B0059301 name: DTX4_HUMAN def: "Protein deltex-4" [UniProtKB:Q9Y2E6] synonym: "Deltex4" EXACT [UniProtKB:Q9Y2E6] synonym: "RING finger protein 155" EXACT [UniProtKB:Q9Y2E6] xref: EMBL:AAI19012.1 xref: EMBL:AAI22862.1 xref: EMBL:BAA76781.1 xref: UniProtKB:Q0VF38 xref: UniProtKB:Q9Y2E6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017628 ! DTX4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: transforms_into CCO:B0064903 ! DTX4_HUMAN-Phosphoserine376 [Term] id: CCO:B0059302 name: CK009_HUMAN def: "Uncharacterized protein C11orf9" [UniProtKB:Q9Y2G1] xref: EMBL:AAF28400.1 xref: EMBL:BAA76798.2 xref: EMBL:EAW73968.1 xref: UniProtKB:Q9P1Q6 xref: UniProtKB:Q9Y2G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017370 ! C11orf9_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059303 name: CARD8_HUMAN def: "Caspase recruitment domain-containing protein 8" [UniProtKB:Q9Y2G2] synonym: "Apoptotic protein NDPP1" EXACT [UniProtKB:Q9Y2G2] synonym: "CARD-inhibitor of NF-kappa-B-activating ligand" EXACT [UniProtKB:Q9Y2G2] synonym: "CARDINAL" EXACT [UniProtKB:Q9Y2G2] synonym: "DACAR" EXACT [UniProtKB:Q9Y2G2] synonym: "TUCAN" EXACT [UniProtKB:Q9Y2G2] synonym: "Tumor up-regulated CARD-containing antagonist of CASP9" EXACT [UniProtKB:Q9Y2G2] xref: EMBL:AAG50014.1 xref: EMBL:AAH56891.1 xref: EMBL:AAK01126.1 xref: EMBL:AAK08982.1 xref: EMBL:AAL02427.1 xref: EMBL:AAM46959.1 xref: EMBL:BAA76799.2 xref: UniProtKB:Q6PGP8 xref: UniProtKB:Q96P82 xref: UniProtKB:Q9Y2G2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017231 ! CARD8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0004943 ! NACHT domain binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0002131 ! regulation of apoptosis relationship: participates_in CCO:P0002163 ! negative regulation of I-kappaB kinase/NF-kappaB cascade relationship: participates_in CCO:P0002178 ! positive regulation of caspase activity [Term] id: CCO:B0059304 name: ZFP30_HUMAN def: "Zinc finger protein 30 homolog" [UniProtKB:Q9Y2G7] synonym: "Zfp-30" EXACT [UniProtKB:Q9Y2G7] synonym: "Zinc finger protein 745" EXACT [UniProtKB:Q9Y2G7] xref: EMBL:AAH41087.1 xref: EMBL:BAA76805.2 xref: UniProtKB:Q58EY8 xref: UniProtKB:Q9Y2G7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020589 ! ZFP30_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059305 name: SBNO2_HUMAN def: "Protein strawberry notch homolog 2" [UniProtKB:Q9Y2G9] xref: EMBL:AAC28919.1 xref: EMBL:AAI06022.1 xref: EMBL:BAA76807.2 xref: EMBL:BAB84928.1 xref: EMBL:BAF85096.1 xref: UniProtKB:A8K8P2 xref: UniProtKB:O75257 xref: UniProtKB:Q3KQX0 xref: UniProtKB:Q8TEM0 xref: UniProtKB:Q9Y2G9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019842 ! SBNO2_human relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0059306 name: ZN510_HUMAN def: "Zinc finger protein 510" [UniProtKB:Q9Y2H8] xref: EMBL:AAH58022.1 xref: EMBL:BAA76816.2 xref: UniProtKB:Q9Y2H8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020788 ! ZNF510_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059307 name: FYV1_HUMAN def: "FYVE finger-containing phosphoinositide kinase" [UniProtKB:Q9Y2I7] synonym: "1-phosphatidylinositol-4-phosphate 5-kinase" EXACT [UniProtKB:Q9Y2I7] synonym: "EC 2.7.1.68" EXACT [UniProtKB:Q9Y2I7] synonym: "p235" EXACT [UniProtKB:Q9Y2I7] synonym: "Phosphatidylinositol-3-phosphate 5-kinase type III" EXACT [UniProtKB:Q9Y2I7] synonym: "PIKfyve" EXACT [UniProtKB:Q9Y2I7] synonym: "PIP5K" EXACT [UniProtKB:Q9Y2I7] synonym: "PtdIns(4)P-5-kinase" EXACT [UniProtKB:Q9Y2I7] xref: EMBL:AAR19397.1 xref: EMBL:BAA76825.1 xref: EMBL:BAC03674.1 xref: UniProtKB:Q8NB67 xref: UniProtKB:Q9Y2I7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017851 ! PIP5K3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0066327 ! FYV1_HUMAN-Phosphotyrosine46 relationship: transforms_into CCO:B0066328 ! FYV1_HUMAN-Phosphoserine307 relationship: transforms_into CCO:B0066329 ! FYV1_HUMAN-Phosphoserine318 relationship: transforms_into CCO:B0066330 ! FYV1_HUMAN-Phosphoserine329 relationship: transforms_into CCO:B0066331 ! FYV1_HUMAN-Phosphotyrosine1155 relationship: transforms_into CCO:B0066332 ! FYV1_HUMAN-Phosphotyrosine1772 [Term] id: CCO:B0059308 name: TBC30_HUMAN def: "TBC1 domain family member 30" [UniProtKB:Q9Y2I9] xref: EMBL:BAA76828.1 xref: UniProtKB:Q9Y2I9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020171 ! TBC1D30_human relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059309 name: ZBTB1_HUMAN def: "Zinc finger and BTB domain-containing protein 1" [UniProtKB:Q9Y2K1] xref: EMBL:AAH50719.1 xref: EMBL:BAA76841.2 xref: EMBL:CAD66584.1 xref: UniProtKB:Q86SW8 xref: UniProtKB:Q9Y2K1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020566 ! ZBTB1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071981 ! ZBTB1_HUMAN-Phosphothreonine169 relationship: transforms_into CCO:B0071982 ! ZBTB1_HUMAN-Phosphoserine355 relationship: transforms_into CCO:B0071983 ! ZBTB1_HUMAN-Phosphothreonine356 [Term] id: CCO:B0059310 name: ZKSC5_HUMAN def: "Zinc finger protein with KRAB and SCAN domains 5" [UniProtKB:Q9Y2L8] synonym: "Zfp-95" EXACT [UniProtKB:Q9Y2L8] synonym: "Zinc finger protein 95 homolog" EXACT [UniProtKB:Q9Y2L8] xref: EMBL:AAF24219.1 xref: EMBL:BAA76859.2 xref: UniProtKB:Q9Y2L8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020612 ! ZKSCAN5_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059311 name: ZN835_HUMAN def: "Zinc finger protein 835" [UniProtKB:Q9Y2P0] xref: EMBL:AAD23609.1 xref: UniProtKB:Q9Y2P0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0022818 ! ZNF835_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059312 name: ZN256_HUMAN def: "Zinc finger protein 256" [UniProtKB:Q9Y2P7] synonym: "BMZF-3" EXACT [UniProtKB:Q9Y2P7] synonym: "Bone marrow zinc finger 3" EXACT [UniProtKB:Q9Y2P7] xref: EMBL:AAD32449.1 xref: EMBL:AAH01438.2 xref: UniProtKB:Q9BV71 xref: UniProtKB:Q9Y2P7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020681 ! ZNF256_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059313 name: ZN257_HUMAN def: "Zinc finger protein 257" [UniProtKB:Q9Y2Q1] synonym: "BMZF-4" EXACT [UniProtKB:Q9Y2Q1] synonym: "Bone marrow zinc finger 4" EXACT [UniProtKB:Q9Y2Q1] xref: EMBL:AAD20957.1 xref: UniProtKB:Q9Y2Q1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020682 ! ZNF257_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059314 name: PTN22_HUMAN def: "Tyrosine-protein phosphatase non-receptor type 22" [UniProtKB:Q9Y2R2] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9Y2R2] synonym: "Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP" EXACT [UniProtKB:Q9Y2R2] synonym: "Lymphoid phosphatase" EXACT [UniProtKB:Q9Y2R2] synonym: "LyP" EXACT [UniProtKB:Q9Y2R2] xref: EMBL:AAD00904.1 xref: EMBL:AAD00905.1 xref: EMBL:AAD27764.1 xref: UniProtKB:O95063 xref: UniProtKB:O95064 xref: UniProtKB:Q9Y2R2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019548 ! PTPN22_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059315 name: AXN2_HUMAN def: "Axin-2" [UniProtKB:Q9Y2T1] synonym: "Axil" EXACT [UniProtKB:Q9Y2T1] synonym: "Axin-like protein" EXACT [UniProtKB:Q9Y2T1] synonym: "Axis inhibition protein 2" EXACT [UniProtKB:Q9Y2T1] synonym: "Conductin" EXACT [UniProtKB:Q9Y2T1] xref: EMBL:AAD20976.1 xref: EMBL:AAF22799.1 xref: EMBL:AAI01534.1 xref: EMBL:BAB19762.1 xref: UniProtKB:Q3MJ88 xref: UniProtKB:Q9H3M6 xref: UniProtKB:Q9UH84 xref: UniProtKB:Q9Y2T1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017106 ! AXIN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway relationship: transforms_into CCO:B0063686 ! AXN2_HUMAN-Phosphoserine630 relationship: transforms_into CCO:B0063687 ! AXN2_HUMAN-Phosphoserine639 relationship: transforms_into CCO:B0063688 ! AXN2_HUMAN-Phosphothreonine640 [Term] id: CCO:B0059316 name: GPR52_HUMAN def: "Probable G-protein coupled receptor 52" [UniProtKB:Q9Y2T5] xref: EMBL:AAD22409.1 xref: EMBL:AAH67456.1 xref: EMBL:AAH67457.1 xref: EMBL:AAH67458.1 xref: EMBL:AAH67459.1 xref: EMBL:AAH67460.1 xref: EMBL:AAH69460.1 xref: EMBL:AAH95532.1 xref: EMBL:CAA18160.1 xref: UniProtKB:O75654 xref: UniProtKB:Q4VBL6 xref: UniProtKB:Q6ISM0 xref: UniProtKB:Q9Y2T5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018024 ! GPR52_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059317 name: GPR55_HUMAN def: "Probable G-protein coupled receptor 55" [UniProtKB:Q9Y2T6] xref: EMBL:AAD22410.1 xref: EMBL:AAH32694.1 xref: EMBL:CAG46575.1 xref: UniProtKB:Q8N580 xref: UniProtKB:Q9Y2T6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018025 ! GPR55_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059318 name: M3K2_HUMAN def: "Mitogen-activated protein kinase kinase kinase 2" [UniProtKB:Q9Y2U5] synonym: "EC 2.7.11.25" EXACT [UniProtKB:Q9Y2U5] synonym: "MAPK/ERK kinase kinase 2" EXACT [UniProtKB:Q9Y2U5] synonym: "MEK kinase 2" EXACT [UniProtKB:Q9Y2U5] synonym: "MEKK 2" EXACT [UniProtKB:Q9Y2U5] xref: EMBL:AAD28547.1 xref: EMBL:AAF63496.1 xref: EMBL:AAY15043.1 xref: EMBL:AAY15070.1 xref: EMBL:BAC11348.1 xref: EMBL:BAD92200.1 xref: UniProtKB:Q53QL9 xref: UniProtKB:Q53S75 xref: UniProtKB:Q59GZ6 xref: UniProtKB:Q8NC32 xref: UniProtKB:Q9NYK3 xref: UniProtKB:Q9Y2U5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018538 ! MAP3K2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016738 ! map3k3-map3k2 physical interaction relationship: participates_in CCO:P0000411 ! activation of MAPK activity relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: transforms_into CCO:B0067811 ! M3K2_HUMAN-Phosphoserine153 relationship: transforms_into CCO:B0067812 ! M3K2_HUMAN-Phosphoserine159 relationship: transforms_into CCO:B0067813 ! M3K2_HUMAN-Phosphoserine163 relationship: transforms_into CCO:B0067814 ! M3K2_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0067815 ! M3K2_HUMAN-Phosphoserine297 relationship: transforms_into CCO:B0067816 ! M3K2_HUMAN-Phosphothreonine304 relationship: transforms_into CCO:B0067817 ! M3K2_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0067818 ! M3K2_HUMAN-Phosphothreonine524 [Term] id: CCO:B0059319 name: RX_HUMAN def: "Retinal homeobox protein Rx" [UniProtKB:Q9Y2V3] synonym: "Retina and anterior neural fold homeobox protein" EXACT [UniProtKB:Q9Y2V3] xref: EMBL:AAD23438.1 xref: UniProtKB:Q9Y2V3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019815 ! RAX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059320 name: TR150_HUMAN def: "Thyroid hormone receptor-associated protein 3" [UniProtKB:Q9Y2W1] synonym: "Thyroid hormone receptor-associated protein complex 150 kDa component" EXACT [UniProtKB:Q9Y2W1] synonym: "Trap150" EXACT [UniProtKB:Q9Y2W1] xref: EMBL:AAD22034.1 xref: EMBL:AAH37554.1 xref: EMBL:AAI12331.1 xref: EMBL:AAI12351.1 xref: EMBL:CAH71859.1 xref: UniProtKB:Q5VTK6 xref: UniProtKB:Q9Y2W1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020339 ! THRAP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: transforms_into CCO:B0071494 ! TR150_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0071495 ! TR150_HUMAN-Phosphoserine211 relationship: transforms_into CCO:B0071496 ! TR150_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0071497 ! TR150_HUMAN-Phosphoserine237 relationship: transforms_into CCO:B0071498 ! TR150_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0071499 ! TR150_HUMAN-Phosphoserine243 relationship: transforms_into CCO:B0071500 ! TR150_HUMAN-Phosphoserine248 relationship: transforms_into CCO:B0071501 ! TR150_HUMAN-Phosphoserine253 relationship: transforms_into CCO:B0071502 ! TR150_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0071503 ! TR150_HUMAN-Phosphoserine268 relationship: transforms_into CCO:B0071504 ! TR150_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0071505 ! TR150_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0071506 ! TR150_HUMAN-Phosphothreonine324 relationship: transforms_into CCO:B0071507 ! TR150_HUMAN-Phosphoserine379 relationship: transforms_into CCO:B0071508 ! TR150_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0071509 ! TR150_HUMAN-Phosphoserine408 relationship: transforms_into CCO:B0071510 ! TR150_HUMAN-Phosphoserine444 relationship: transforms_into CCO:B0071511 ! TR150_HUMAN-Phosphoserine508 relationship: transforms_into CCO:B0071512 ! TR150_HUMAN-Phosphoserine534 relationship: transforms_into CCO:B0071513 ! TR150_HUMAN-Phosphoserine535 relationship: transforms_into CCO:B0071514 ! TR150_HUMAN-Phosphoserine575 relationship: transforms_into CCO:B0071515 ! TR150_HUMAN-Phosphothreonine662 relationship: transforms_into CCO:B0071516 ! TR150_HUMAN-Phosphoserine672 relationship: transforms_into CCO:B0071517 ! TR150_HUMAN-Phosphoserine682 relationship: transforms_into CCO:B0071518 ! TR150_HUMAN-Phosphoserine684 relationship: transforms_into CCO:B0071519 ! TR150_HUMAN-Phosphoserine698 relationship: transforms_into CCO:B0071520 ! TR150_HUMAN-Phosphoserine823 relationship: transforms_into CCO:B0071521 ! TR150_HUMAN-Phosphothreonine833 relationship: transforms_into CCO:B0071522 ! TR150_HUMAN-Phosphothreonine874 relationship: transforms_into CCO:B0071523 ! TR150_HUMAN-Phosphoserine928 relationship: transforms_into CCO:B0071524 ! TR150_HUMAN-Phosphoserine939 relationship: transforms_into CCO:B0071525 ! TR150_HUMAN-Phosphothreonine941 [Term] id: CCO:B0059321 name: ZN281_HUMAN def: "Zinc finger protein 281" [UniProtKB:Q9Y2X9] synonym: "GC-box-binding zinc finger protein 1" EXACT [UniProtKB:Q9Y2X9] synonym: "Transcription factor ZBP-99" EXACT [UniProtKB:Q9Y2X9] synonym: "Zinc finger DNA-binding protein 99" EXACT [UniProtKB:Q9Y2X9] xref: EMBL:AAD21084.1 xref: EMBL:AAH60820.1 xref: EMBL:CAB70967.1 xref: EMBL:CAB70968.1 xref: UniProtKB:Q9NY92 xref: UniProtKB:Q9Y2X9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020691 ! ZNF281_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0072086 ! ZN281_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0072087 ! ZN281_HUMAN-Phosphoserine484 relationship: transforms_into CCO:B0072088 ! ZN281_HUMAN-Phosphoserine785 relationship: transforms_into CCO:B0072089 ! ZN281_HUMAN-Phosphoserine807 [Term] id: CCO:B0059322 name: AR2BP_HUMAN def: "ADP-ribosylation factor-like protein 2-binding protein" [UniProtKB:Q9Y2Y0] synonym: "ARF-like 2-binding protein" EXACT [UniProtKB:Q9Y2Y0] synonym: "Binder of ARF2 protein 1" EXACT [UniProtKB:Q9Y2Y0] xref: EMBL:AAD20633.1 xref: EMBL:AAH03087.1 xref: EMBL:AAH94878.1 xref: UniProtKB:Q504R0 xref: UniProtKB:Q9Y2Y0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016998 ! ARL2BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065695 ! AR2BP_HUMAN-Phosphoserine157 [Term] id: CCO:B0059323 name: RPC10_HUMAN def: "DNA-directed RNA polymerase III subunit RPC10" [UniProtKB:Q9Y2Y1] synonym: "DNA-directed RNA polymerase III subunit K" EXACT [UniProtKB:Q9Y2Y1] synonym: "DNA-directed RNA polymerases III 12.5 kDa polypeptide" EXACT [UniProtKB:Q9Y2Y1] synonym: "hRPC11" EXACT [UniProtKB:Q9Y2Y1] synonym: "HsC11p" EXACT [UniProtKB:Q9Y2Y1] synonym: "RNA polymerase III subunit C10" EXACT [UniProtKB:Q9Y2Y1] synonym: "RNA polymerase III subunit C11" EXACT [UniProtKB:Q9Y2Y1] synonym: "RPC11" EXACT [UniProtKB:Q9Y2Y1] xref: EMBL:AAD31424.1 xref: EMBL:AAF18268.1 xref: EMBL:AAG43123.1 xref: EMBL:AAH11932.1 xref: EMBL:AAK61210.1 xref: EMBL:ABD95903.1 xref: EMBL:CAI95605.1 xref: UniProtKB:Q1W6H4 xref: UniProtKB:Q96S35 xref: UniProtKB:Q9Y2Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019781 ! POLR3K_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000271 ! DNA-directed RNA polymerase III complex relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059324 name: ZBT32_HUMAN def: "Zinc finger and BTB domain-containing protein 32" [UniProtKB:Q9Y2Y4] synonym: "FANCC-interacting protein" EXACT [UniProtKB:Q9Y2Y4] synonym: "Fanconi anemia zinc finger protein" EXACT [UniProtKB:Q9Y2Y4] synonym: "Testis zinc finger protein" EXACT [UniProtKB:Q9Y2Y4] xref: EMBL:AAD27708.1 xref: EMBL:AAD48448.1 xref: EMBL:AAH17700.1 xref: UniProtKB:Q8WVP2 xref: UniProtKB:Q9Y2Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020552 ! ZBTB32_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017567 ! fazf-atxn1 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059325 name: PRG3_HUMAN def: "Proteoglycan 3 precursor" [UniProtKB:Q9Y2Y8] synonym: "Eosinophil major basic protein homolog" EXACT [UniProtKB:Q9Y2Y8] synonym: "Prepro-major basic protein homolog" EXACT [UniProtKB:Q9Y2Y8] synonym: "Prepro-MBPH" EXACT [UniProtKB:Q9Y2Y8] xref: EMBL:AAD24471.1 xref: EMBL:AAG41952.1 xref: EMBL:AAH69126.1 xref: EMBL:AAI01614.1 xref: EMBL:AAI13412.1 xref: EMBL:AAQ89289.1 xref: UniProtKB:Q9Y2Y8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019506 ! PRG3_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002357 ! positive regulation of interleukin-8 biosynthetic process [Term] id: CCO:B0059326 name: KLF13_HUMAN def: "Krueppel-like factor 13" [UniProtKB:Q9Y2Y9] synonym: "Basic transcription element-binding protein 3" EXACT [UniProtKB:Q9Y2Y9] synonym: "BTE-binding protein 3" EXACT [UniProtKB:Q9Y2Y9] synonym: "Novel Sp1-like zinc finger transcription factor 1" EXACT [UniProtKB:Q9Y2Y9] synonym: "RANTES factor of late activated T-lymphocytes 1" EXACT [UniProtKB:Q9Y2Y9] synonym: "RFLAT-1" EXACT [UniProtKB:Q9Y2Y9] synonym: "Transcription factor BTEB3" EXACT [UniProtKB:Q9Y2Y9] synonym: "Transcription factor NSLP1" EXACT [UniProtKB:Q9Y2Y9] xref: EMBL:AAD26864.1 xref: EMBL:AAD34020.1 xref: EMBL:AAH10438.1 xref: EMBL:AAH12741.1 xref: EMBL:AAH13946.1 xref: UniProtKB:Q9Y2Y9 xref: UniProtKB:Q9Y356 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018411 ! KLF13_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0059327 name: GPR89_HUMAN def: "Protein GPR89" [UniProtKB:Q9Y302] synonym: "Putative MAPK-activating protein PM01" EXACT [UniProtKB:Q9Y302] synonym: "Putative NF-kappa-B-activating protein 90" EXACT [UniProtKB:Q9Y302] xref: EMBL:AAD27722.1 xref: EMBL:AAF21463.1 xref: EMBL:AAF36121.1 xref: EMBL:AAH03187.1 xref: EMBL:AAH67816.1 xref: EMBL:AAP35325.1 xref: EMBL:AAQ89325.1 xref: EMBL:BAC77377.1 xref: EMBL:BAC77378.1 xref: EMBL:BAD96943.1 xref: EMBL:CAH56393.1 xref: EMBL:CAH72386.1 xref: EMBL:CAI13224.2 xref: EMBL:CAI13712.2 xref: EMBL:CAI18821.1 xref: EMBL:CAM28366.1 xref: UniProtKB:A6NN37 xref: UniProtKB:Q53FQ9 xref: UniProtKB:Q5T2V8 xref: UniProtKB:Q5T5P5 xref: UniProtKB:Q659E2 xref: UniProtKB:Q6NVY5 xref: UniProtKB:Q9P0S4 xref: UniProtKB:Q9Y302 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018040 ! GPR89A_human relationship: encoded_by CCO:G0018041 ! GPR89B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0059328 name: NSG2_HUMAN def: "Neuron-specific protein family member 2" [UniProtKB:Q9Y328] synonym: "HMP19" EXACT [UniProtKB:Q9Y328] synonym: "Protein p19" EXACT [UniProtKB:Q9Y328] xref: EMBL:AAD30539.1 xref: EMBL:AAF14874.1 xref: EMBL:AAH02619.1 xref: UniProtKB:Q9UHX8 xref: UniProtKB:Q9Y328 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018877 ! NSG2_human relationship: has_function CCO:F0008009 ! dopamine receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:P0000747 ! dopamine receptor signaling pathway [Term] id: CCO:B0059329 name: ZBT12_HUMAN def: "Zinc finger and BTB domain-containing protein 12" [UniProtKB:Q9Y330] synonym: "Protein G10" EXACT [UniProtKB:Q9Y330] xref: EMBL:AAD21810.1 xref: EMBL:AAH43609.1 xref: EMBL:BAB63293.1 xref: EMBL:CAI17750.1 xref: EMBL:CAI18229.1 xref: EMBL:CAI41855.1 xref: UniProtKB:Q5JQ98 xref: UniProtKB:Q9Y330 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020545 ! ZBTB12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0071958 ! ZBT12_HUMAN-Phosphothreonine19 [Term] id: CCO:B0059330 name: SIGL9_HUMAN def: "Sialic acid-binding Ig-like lectin 9 precursor" [UniProtKB:Q9Y336] synonym: "Protein FOAP-9" EXACT [UniProtKB:Q9Y336] synonym: "Siglec-9" EXACT [UniProtKB:Q9Y336] xref: EMBL:AAD26428.2 xref: EMBL:AAF71455.1 xref: EMBL:AAF87223.1 xref: EMBL:AAG23261.1 xref: EMBL:AAQ89272.1 xref: EMBL:BAB41100.1 xref: UniProtKB:Q9BYI9 xref: UniProtKB:Q9Y336 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019907 ! SIGLEC9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:B0059331 name: Q9Y347_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q9Y347] xref: EMBL:AAD33911.1 xref: UniProtKB:Q9Y347 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021283 ! OR52K3P_human relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059332 name: IFT52_HUMAN def: "Intraflagellar transport protein 52 homolog" [UniProtKB:Q9Y366] synonym: "Protein NGD5 homolog" EXACT [UniProtKB:Q9Y366] xref: EMBL:AAD34048.1 xref: EMBL:AAH39831.1 xref: EMBL:CAI18925.1 xref: EMBL:CAI42316.1 xref: UniProtKB:Q5H8Z0 xref: UniProtKB:Q9H1G3 xref: UniProtKB:Q9H1G4 xref: UniProtKB:Q9H1H2 xref: UniProtKB:Q9Y366 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018234 ! IFT52_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000758 ! smoothened signaling pathway relationship: participates_in CCO:P0002579 ! positive regulation of proteolysis [Term] id: CCO:B0059333 name: SHLB1_HUMAN def: "Endophilin-B1" [UniProtKB:Q9Y371] synonym: "Bax-interacting factor 1" EXACT [UniProtKB:Q9Y371] synonym: "Bif-1" EXACT [UniProtKB:Q9Y371] synonym: "SH3 domain-containing GRB2-like protein B1" EXACT [UniProtKB:Q9Y371] xref: EMBL:AAD34056.1 xref: EMBL:AAF73017.1 xref: EMBL:AAF81225.1 xref: EMBL:AAH07455.1 xref: EMBL:AAK27365.1 xref: EMBL:BAA91999.1 xref: EMBL:BAD88797.1 xref: EMBL:CAC10394.1 xref: EMBL:CAC10395.1 xref: UniProtKB:Q5H8U5 xref: UniProtKB:Q9H3Z0 xref: UniProtKB:Q9NR47 xref: UniProtKB:Q9NYA9 xref: UniProtKB:Q9Y371 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019898 ! SH3GLB1_human relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005636 ! lysophosphatidic acid acyltransferase activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: participates_in CCO:P0000481 ! protein insertion into mitochondrial membrane during induction of apoptosis relationship: participates_in CCO:P0000671 ! anti-apoptosis [Term] id: CCO:B0059334 name: UTP11_HUMAN def: "Probable U3 small nucleolar RNA-associated protein 11" [UniProtKB:Q9Y3A2] synonym: "U3 snoRNA-associated protein 11" EXACT [UniProtKB:Q9Y3A2] synonym: "UTP11-like protein" EXACT [UniProtKB:Q9Y3A2] xref: EMBL:AAD34089.1 xref: EMBL:AAF75562.1 xref: EMBL:AAH05182.1 xref: EMBL:CAH69932.1 xref: UniProtKB:Q5VT93 xref: UniProtKB:Q9BS98 xref: UniProtKB:Q9NS31 xref: UniProtKB:Q9Y3A2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020426 ! UTP11L_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0002175 ! small-subunit processome relationship: participates_in CCO:P0000672 ! induction of apoptosis relationship: participates_in CCO:P0002757 ! nerve growth factor receptor signaling pathway relationship: transforms_into CCO:B0071765 ! UTP11_HUMAN-Phosphotyrosine50 [Term] id: CCO:B0059335 name: GOT1B_HUMAN def: "Vesicle transport protein GOT1B" [UniProtKB:Q9Y3E0] synonym: "Golgi transport 1 homolog B" EXACT [UniProtKB:Q9Y3E0] synonym: "hGOT1a" EXACT [UniProtKB:Q9Y3E0] synonym: "Putative NF-kappa-B-activating protein 470" EXACT [UniProtKB:Q9Y3E0] xref: EMBL:AAD34136.1 xref: EMBL:AAF65181.1 xref: EMBL:AAH12455.1 xref: EMBL:AAQ89334.1 xref: EMBL:BAC77373.1 xref: EMBL:CAB66506.1 xref: EMBL:CAG33670.1 xref: UniProtKB:Q54A40 xref: UniProtKB:Q6I9W6 xref: UniProtKB:Q9P1R9 xref: UniProtKB:Q9Y3E0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017952 ! GOLT1B_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002162 ! positive regulation of I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0059336 name: HDGR3_HUMAN def: "Hepatoma-derived growth factor-related protein 3" [UniProtKB:Q9Y3E1] synonym: "Hepatoma-derived growth factor 2" EXACT [UniProtKB:Q9Y3E1] synonym: "HRP-3" EXACT [UniProtKB:Q9Y3E1] xref: EMBL:AAD34137.1 xref: EMBL:AAH15483.1 xref: EMBL:AAH40554.1 xref: EMBL:AAM27001.1 xref: EMBL:BAA90477.1 xref: EMBL:BAA91597.1 xref: UniProtKB:Q9Y3E1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018111 ! HDGFRP3_human relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059337 name: GBG5L_HUMAN xref: UniProtKB:Q9Y3K8 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059338 name: 3BP1_HUMAN def: "SH3 domain-binding protein 1" [UniProtKB:Q9Y3L3] synonym: "3BP-1" EXACT [UniProtKB:Q9Y3L3] xref: EMBL:AAH08282.1 xref: EMBL:BAC85842.1 xref: EMBL:CAB75671.2 xref: EMBL:CAG30462.1 xref: EMBL:CAI20370.2 xref: UniProtKB:Q5R3N0 xref: UniProtKB:Q6IBZ2 xref: UniProtKB:Q6ZVL9 xref: UniProtKB:Q96HQ5 xref: UniProtKB:Q9NSQ9 xref: UniProtKB:Q9Y3L3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016844 ! SH3BP1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018431 ! hck-sh3bp1-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059339 name: CBY1_HUMAN def: "Protein chibby homolog 1" [UniProtKB:Q9Y3M2] synonym: "ARPP-binding protein" EXACT [UniProtKB:Q9Y3M2] synonym: "Cytosolic leucine-rich protein" EXACT [UniProtKB:Q9Y3M2] synonym: "PIGEA-14" EXACT [UniProtKB:Q9Y3M2] synonym: "PKD2 interactor, Golgi and endoplasmic reticulum-associated 1" EXACT [UniProtKB:Q9Y3M2] xref: EMBL:AAH16139.1 xref: EMBL:AAL56062.1 xref: EMBL:BAA88119.1 xref: EMBL:BAC78839.1 xref: EMBL:CAB43547.1 xref: EMBL:CAB63442.1 xref: EMBL:CAB66621.1 xref: EMBL:CAG30296.1 xref: EMBL:DAA05582.1 xref: EMBL:EAW60254.1 xref: UniProtKB:Q66GT6 xref: UniProtKB:Q9UIK9 xref: UniProtKB:Q9Y3M2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017254 ! CBY1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway relationship: participates_in CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:B0059340 name: ZN337_HUMAN def: "Zinc finger protein 337" [UniProtKB:Q9Y3M9] xref: EMBL:AAH21298.1 xref: EMBL:CAB43216.1 xref: EMBL:CAB43548.2 xref: UniProtKB:Q9Y3M9 xref: UniProtKB:Q9Y3Y5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020711 ! ZNF337_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019949 ! commd3-znf337 physical interaction relationship: participates_in CCO:I0020516 ! atp5c1-znf337 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059341 name: OR2W1_HUMAN def: "Olfactory receptor 2W1" [UniProtKB:Q9Y3N9] synonym: "Hs6M1-15" EXACT [UniProtKB:Q9Y3N9] synonym: "Olfactory receptor OR6-13" EXACT [UniProtKB:Q9Y3N9] xref: EMBL:AAI03871.1 xref: EMBL:AAI03872.1 xref: EMBL:AAI03873.1 xref: EMBL:AAK95113.1 xref: EMBL:CAB42853.1 xref: EMBL:CAC20514.1 xref: EMBL:CAC20515.1 xref: EMBL:CAC20516.1 xref: EMBL:CAC20517.1 xref: EMBL:CAC20518.1 xref: EMBL:CAC20519.1 xref: EMBL:CAC20520.1 xref: EMBL:CAC20521.1 xref: EMBL:CAC20522.1 xref: EMBL:CAC20523.1 xref: EMBL:CAI18243.1 xref: EMBL:CAI41643.1 xref: EMBL:CAI41768.2 xref: EMBL:CAM26052.1 xref: EMBL:DAA04920.1 xref: UniProtKB:Q5JNZ1 xref: UniProtKB:Q6IEU0 xref: UniProtKB:Q96R17 xref: UniProtKB:Q9GZL0 xref: UniProtKB:Q9GZL1 xref: UniProtKB:Q9Y3N9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019124 ! OR2W1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059342 name: SIT1_HUMAN def: "Signaling threshold-regulating transmembrane adapter 1 precursor" [UniProtKB:Q9Y3P8] synonym: "gp30/40" EXACT [UniProtKB:Q9Y3P8] synonym: "SHP2-interacting transmembrane adapter protein" EXACT [UniProtKB:Q9Y3P8] synonym: "Suppression-inducing transmembrane adapter 1" EXACT [UniProtKB:Q9Y3P8] xref: EMBL:AAI02030.1 xref: EMBL:AAI04492.1 xref: EMBL:AAI07485.1 xref: EMBL:CAB41504.1 xref: EMBL:CAC81313.1 xref: EMBL:CAI13446.1 xref: UniProtKB:Q9Y3P8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019918 ! SIT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002981 ! regulation of T cell activation relationship: transforms_into CCO:B0070550 ! SIT1_HUMAN-Phosphoserine80 relationship: transforms_into CCO:B0070551 ! SIT1_HUMAN-Phosphoserine83 relationship: transforms_into CCO:B0070552 ! SIT1_HUMAN-Phosphotyrosine90 relationship: transforms_into CCO:B0070553 ! SIT1_HUMAN-Phosphotyrosine95 relationship: transforms_into CCO:B0070554 ! SIT1_HUMAN-Phosphothreonine98 relationship: transforms_into CCO:B0070555 ! SIT1_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0070556 ! SIT1_HUMAN-Phosphotyrosine127 relationship: transforms_into CCO:B0070557 ! SIT1_HUMAN-Phosphothreonine144 relationship: transforms_into CCO:B0070558 ! SIT1_HUMAN-Phosphotyrosine148 relationship: transforms_into CCO:B0070559 ! SIT1_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0070560 ! SIT1_HUMAN-Phosphotyrosine169 relationship: transforms_into CCO:B0070561 ! SIT1_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0070562 ! SIT1_HUMAN-Phosphotyrosine188 [Term] id: CCO:B0059343 name: GRIP1_HUMAN def: "Glutamate receptor-interacting protein 1" [UniProtKB:Q9Y3R0] synonym: "GRIP1 protein" EXACT [UniProtKB:Q9Y3R0] xref: EMBL:CAB39895.1 xref: UniProtKB:Q9Y3R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018069 ! GRIP1_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:B0059344 name: WNK2_HUMAN def: "Serine/threonine-protein kinase WNK2" [UniProtKB:Q9Y3S1] synonym: "Antigen NY-CO-43" EXACT [UniProtKB:Q9Y3S1] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y3S1] synonym: "Protein kinase with no lysine 2" EXACT [UniProtKB:Q9Y3S1] synonym: "Protein kinase, lysine-deficient 2" EXACT [UniProtKB:Q9Y3S1] synonym: "Serologically defined colon cancer antigen 43" EXACT [UniProtKB:Q9Y3S1] xref: EMBL:AAH37965.1 xref: EMBL:BAB18648.1 xref: EMBL:BAB21851.2 xref: EMBL:CAB44308.5 xref: UniProtKB:Q8IY36 xref: UniProtKB:Q9C0A3 xref: UniProtKB:Q9H3P4 xref: UniProtKB:Q9Y3S1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020481 ! WNK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019012 ! atxn1-wnk2 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: transforms_into CCO:B0071861 ! WNK2_HUMAN-Phosphoserine352 relationship: transforms_into CCO:B0071862 ! WNK2_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0071863 ! WNK2_HUMAN-Phosphoserine1817 relationship: transforms_into CCO:B0071864 ! WNK2_HUMAN-Phosphoserine1818 [Term] id: CCO:B0059345 name: PYGO1_HUMAN def: "Pygopus homolog 1" [UniProtKB:Q9Y3Y4] xref: EMBL:AAL91370.1 xref: EMBL:CAB43209.1 xref: UniProtKB:Q9Y3Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019564 ! PYGO1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0059346 name: Q9Y408_HUMAN def: "Putative uncharacterized protein DKFZp566D133" [UniProtKB:Q9Y408] xref: EMBL:CAB43250.1 xref: UniProtKB:Q9Y408 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021284 ! GARNL2P_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction [Term] id: CCO:B0059347 name: HBS1L_HUMAN def: "HBS1-like protein" [UniProtKB:Q9Y450] synonym: "ERFS" EXACT [UniProtKB:Q9Y450] xref: EMBL:AAD00645.1 xref: EMBL:AAH01465.1 xref: EMBL:AAH40849.1 xref: EMBL:BAA82990.1 xref: EMBL:CAD30873.1 xref: EMBL:CAD30874.1 xref: EMBL:CAI17912.1 xref: EMBL:CAI17913.1 xref: EMBL:CAI17914.1 xref: UniProtKB:Q5T7G3 xref: UniProtKB:Q8NDW9 xref: UniProtKB:Q9UPW3 xref: UniProtKB:Q9Y450 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018106 ! HBS1L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059348 name: ZN711_HUMAN def: "Zinc finger protein 711" [UniProtKB:Q9Y462] synonym: "Zinc finger protein 6" EXACT [UniProtKB:Q9Y462] xref: EMBL:AAH67294.1 xref: EMBL:CAA39837.2 xref: UniProtKB:Q6NX42 xref: UniProtKB:Q9Y462 xref: UniProtKB:Q9Y4J6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020914 ! ZNF711_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0072226 ! ZN711_HUMAN-Phosphoserine210 [Term] id: CCO:B0059349 name: DYR1B_HUMAN def: "Dual specificity tyrosine-phosphorylation-regulated kinase 1B" [UniProtKB:Q9Y463] synonym: "EC 2.7.12.1" EXACT [UniProtKB:Q9Y463] synonym: "Minibrain-related kinase" EXACT [UniProtKB:Q9Y463] synonym: "Mirk protein kinase" EXACT [UniProtKB:Q9Y463] xref: EMBL:AAC28914.1 xref: EMBL:AAF15893.1 xref: EMBL:AAH18751.1 xref: EMBL:AAH25291.1 xref: EMBL:CAA76989.1 xref: EMBL:CAA76990.1 xref: EMBL:CAA76991.1 xref: UniProtKB:O75258 xref: UniProtKB:O75788 xref: UniProtKB:O75789 xref: UniProtKB:Q9Y463 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017649 ! DYRK1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015947 ! dyrk1b-map2k3-1 physical interaction relationship: participates_in CCO:I0016123 ! dyrk1b-ranbp9-3 physical interaction relationship: participates_in CCO:I0016287 ! dyrk1b-ranbp9-2 direct interaction relationship: participates_in CCO:I0016288 ! dyrk1b-tcf1-3 phosphorylation relationship: participates_in CCO:I0017746 ! dyrk1b-dcohm-1 physical interaction relationship: participates_in CCO:I0018066 ! dyrk1b-ranbp9-4 physical interaction relationship: participates_in CCO:I0018323 ! dyrk1b-dcohm-2 direct interaction relationship: participates_in CCO:I0018324 ! dyrk1b-dcohm-3 physical interaction relationship: participates_in CCO:I0018325 ! dyrk1b-tcf1-1 direct interaction relationship: participates_in CCO:I0018649 ! dyrk1b-map2k3-2 phosphorylation relationship: participates_in CCO:I0018650 ! dyrk1b-tcf1-2 phosphorylation relationship: participates_in CCO:I0019499 ! dyrk1b-ranbp9-1 physical interaction relationship: participates_in CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064908 ! DYR1B_HUMAN-Phosphotyrosine271 relationship: transforms_into CCO:B0064909 ! DYR1B_HUMAN-Phosphotyrosine273 [Term] id: CCO:B0059350 name: NR2E1_HUMAN def: "Nuclear receptor subfamily 2 group E member 1" [UniProtKB:Q9Y466] synonym: "hTll" EXACT [UniProtKB:Q9Y466] synonym: "Nuclear receptor TLX" EXACT [UniProtKB:Q9Y466] synonym: "Protein tailless homolog" EXACT [UniProtKB:Q9Y466] synonym: "Tll" EXACT [UniProtKB:Q9Y466] xref: EMBL:AAG31945.1 xref: EMBL:AAH28031.1 xref: EMBL:AAL05871.1 xref: EMBL:CAA73725.1 xref: EMBL:CAB75626.1 xref: UniProtKB:Q9Y466 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018858 ! NR2E1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0068820 ! NR2E1_HUMAN-Phosphoserine301 [Term] id: CCO:B0059351 name: SALL2_HUMAN def: "Sal-like protein 2" [UniProtKB:Q9Y467] synonym: "HSal2" EXACT [UniProtKB:Q9Y467] synonym: "Zinc finger protein SALL2" EXACT [UniProtKB:Q9Y467] xref: EMBL:AAL74188.1 xref: EMBL:BAA21638.2 xref: UniProtKB:Q9Y467 xref: UniProtKB:Q9Y4G1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019833 ! SALL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070313 ! SALL2_HUMAN-Phosphoserine609 relationship: transforms_into CCO:B0070314 ! SALL2_HUMAN-Phosphothreonine616 relationship: transforms_into CCO:B0070315 ! SALL2_HUMAN-Phosphoserine623 [Term] id: CCO:B0059352 name: LMBL1_HUMAN def: "Lethal(3)malignant brain tumor-like protein" [UniProtKB:Q9Y468] synonym: "H-L(3)MBT" EXACT [UniProtKB:Q9Y468] synonym: "H-l(3)mbt protein" EXACT [UniProtKB:Q9Y468] synonym: "L(3)mbt protein homolog" EXACT [UniProtKB:Q9Y468] synonym: "L(3)mbt-like" EXACT [UniProtKB:Q9Y468] synonym: "L3MBTL1" EXACT [UniProtKB:Q9Y468] xref: EMBL:AAC69438.1 xref: EMBL:AAH39820.1 xref: EMBL:BAA31656.1 xref: EMBL:CAB53714.1 xref: EMBL:CAC16800.1 xref: EMBL:CAC18508.1 xref: EMBL:CAI23043.1 xref: EMBL:CAI42318.1 xref: UniProtKB:Q5H8Y8 xref: UniProtKB:Q8IUV7 xref: UniProtKB:Q9H1E6 xref: UniProtKB:Q9H1G5 xref: UniProtKB:Q9UG06 xref: UniProtKB:Q9UJB9 xref: UniProtKB:Q9Y468 xref: UniProtKB:Q9Y4C9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018504 ! L3MBTL_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059353 name: AAKB1_HUMAN def: "5'-AMP-activated protein kinase subunit beta-1" [UniProtKB:Q9Y478] synonym: "AMPK beta-1 chain" EXACT [UniProtKB:Q9Y478] synonym: "AMPKb" EXACT [UniProtKB:Q9Y478] xref: EMBL:AAB71326.1 xref: EMBL:AAC98897.1 xref: EMBL:AAD00625.1 xref: EMBL:AAD09237.1 xref: EMBL:AAH01007.1 xref: EMBL:AAH01056.1 xref: EMBL:AAH01823.1 xref: EMBL:AAH17671.1 xref: EMBL:CAA12024.1 xref: EMBL:CAA73146.1 xref: UniProtKB:Q9UBV0 xref: UniProtKB:Q9UE20 xref: UniProtKB:Q9UEX2 xref: UniProtKB:Q9Y478 xref: UniProtKB:Q9Y6V8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016865 ! PRKAB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007179 ! prkaa1-aakg1-1 physical interaction relationship: participates_in CCO:I0020307 ! f10-prkab1 physical interaction relationship: participates_in CCO:I0020381 ! ndufa7-prkab1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0065231 ! AAKB1_HUMAN-Phosphothreonine4 relationship: transforms_into CCO:B0065232 ! AAKB1_HUMAN-Phosphoserine5 relationship: transforms_into CCO:B0065233 ! AAKB1_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0065234 ! AAKB1_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0065235 ! AAKB1_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0065236 ! AAKB1_HUMAN-Phosphoserine96 relationship: transforms_into CCO:B0065237 ! AAKB1_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0065238 ! AAKB1_HUMAN-Phosphoserine108 relationship: transforms_into CCO:B0065239 ! AAKB1_HUMAN-Phosphoserine182 [Term] id: CCO:B0059354 name: Q9Y4A3_HUMAN def: "R33590_1" [UniProtKB:Q9Y4A3] xref: EMBL:AAC34469.1 xref: UniProtKB:Q9Y4A3 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059355 name: NF2L3_HUMAN def: "Nuclear factor erythroid 2-related factor 3" [UniProtKB:Q9Y4A8] synonym: "NF-E2-related factor 3" EXACT [UniProtKB:Q9Y4A8] synonym: "NFE2-related factor 3" EXACT [UniProtKB:Q9Y4A8] synonym: "Nuclear factor, erythroid derived 2, like 3" EXACT [UniProtKB:Q9Y4A8] xref: EMBL:AAF61404.1 xref: EMBL:AAF61415.1 xref: EMBL:AAG43275.1 xref: EMBL:AAH49219.1 xref: EMBL:AAH56142.1 xref: EMBL:AAH68455.1 xref: EMBL:AAP22344.1 xref: EMBL:BAA76288.1 xref: UniProtKB:Q6NUS0 xref: UniProtKB:Q7Z498 xref: UniProtKB:Q86UJ4 xref: UniProtKB:Q86VR5 xref: UniProtKB:Q9UQA4 xref: UniProtKB:Q9Y4A8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018764 ! NFE2L3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059356 name: O10H1_HUMAN def: "Olfactory receptor 10H1" [UniProtKB:Q9Y4A9] xref: EMBL:AAC08454.1 xref: EMBL:AAK95069.1 xref: UniProtKB:Q96R59 xref: UniProtKB:Q9Y4A9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018914 ! OR10H1_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059357 name: JHD2A_HUMAN def: "JmjC domain-containing histone demethylation protein 2A" [UniProtKB:Q9Y4C1] synonym: "EC 1.14.11.-" EXACT [UniProtKB:Q9Y4C1] synonym: "Jumonji domain-containing protein 1A" EXACT [UniProtKB:Q9Y4C1] xref: EMBL:AAY24210.1 xref: EMBL:BAA34462.2 xref: EMBL:CAE45820.1 xref: EMBL:CAH18373.1 xref: EMBL:CAH18459.3 xref: UniProtKB:Q53S72 xref: UniProtKB:Q68D47 xref: UniProtKB:Q68UT9 xref: UniProtKB:Q6N050 xref: UniProtKB:Q8IY08 xref: UniProtKB:Q9Y4C1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018359 ! JMJD1A_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000861 ! hormone-mediated signaling relationship: participates_in CCO:P0001280 ! androgen receptor signaling pathway relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0059358 name: MFHA1_HUMAN def: "Malignant fibrous histiocytoma-amplified sequence 1" [UniProtKB:Q9Y4C4] synonym: "Malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1" EXACT [UniProtKB:Q9Y4C4] xref: EMBL:AAH14226.2 xref: EMBL:BAA74737.1 xref: UniProtKB:Q96CI0 xref: UniProtKB:Q9Y4C4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018610 ! MFHAS1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: transforms_into CCO:B0068151 ! MFHA1_HUMAN-Phosphotyrosine447 relationship: transforms_into CCO:B0068152 ! MFHA1_HUMAN-Phosphoserine450 relationship: transforms_into CCO:B0068153 ! MFHA1_HUMAN-Phosphoserine455 relationship: transforms_into CCO:B0068154 ! MFHA1_HUMAN-Phosphoserine468 [Term] id: CCO:B0059359 name: PLXD1_HUMAN def: "Plexin-D1 precursor" [UniProtKB:Q9Y4D7] xref: EMBL:AAH03526.1 xref: EMBL:AAH11848.1 xref: EMBL:AAM49063.1 xref: EMBL:BAA31595.1 xref: UniProtKB:Q6PJS9 xref: UniProtKB:Q8IZJ2 xref: UniProtKB:Q9BTQ2 xref: UniProtKB:Q9Y4D7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019452 ! PLXND1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059360 name: FARP1_HUMAN def: "FERM, RhoGEF and pleckstrin domain-containing protein 1" [UniProtKB:Q9Y4F1] synonym: "Chondrocyte-derived ezrin-like protein" EXACT [UniProtKB:Q9Y4F1] xref: EMBL:AAH41595.1 xref: EMBL:AAH71592.1 xref: EMBL:BAA24267.1 xref: EMBL:CAI10953.1 xref: EMBL:CAI12946.1 xref: EMBL:CAI39458.1 xref: UniProtKB:Q6IQ29 xref: UniProtKB:Q9Y4F1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017763 ! FARP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001985 ! regulation of Rho protein signal transduction relationship: transforms_into CCO:B0066123 ! FARP1_HUMAN-Phosphothreonine24 relationship: transforms_into CCO:B0066124 ! FARP1_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0066125 ! FARP1_HUMAN-Phosphoserine340 relationship: transforms_into CCO:B0066126 ! FARP1_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0066127 ! FARP1_HUMAN-Phosphoserine889 relationship: transforms_into CCO:B0066128 ! FARP1_HUMAN-Phosphoserine896 relationship: transforms_into CCO:B0066129 ! FARP1_HUMAN-Phosphothreonine898 relationship: transforms_into CCO:B0066130 ! FARP1_HUMAN-Phosphoserine899 [Term] id: CCO:B0059361 name: PKHM1_HUMAN def: "Pleckstrin homology domain-containing family M member 1" [UniProtKB:Q9Y4G2] synonym: "162 kDa adapter protein" EXACT [UniProtKB:Q9Y4G2] synonym: "AP162" EXACT [UniProtKB:Q9Y4G2] xref: EMBL:AAH64361.1 xref: EMBL:BAA20813.2 xref: EMBL:BAB84929.1 xref: EMBL:CAB91652.1 xref: EMBL:CAB97526.1 xref: UniProtKB:Q6P2R5 xref: UniProtKB:Q8TEL9 xref: UniProtKB:Q9NPP5 xref: UniProtKB:Q9NYA0 xref: UniProtKB:Q9Y4G2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019420 ! PLEKHM1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: transforms_into CCO:B0069359 ! PKHM1_HUMAN-Phosphoserine435 [Term] id: CCO:B0059362 name: RPGF2_HUMAN def: "Rap guanine nucleotide exchange factor 2" [UniProtKB:Q9Y4G8] synonym: "Neural RAP guanine nucleotide exchange protein" EXACT [UniProtKB:Q9Y4G8] synonym: "nRap GEP" EXACT [UniProtKB:Q9Y4G8] synonym: "PDZ domain-containing guanine nucleotide exchange factor 1" EXACT [UniProtKB:Q9Y4G8] synonym: "PDZ-GEF1" EXACT [UniProtKB:Q9Y4G8] synonym: "RA-GEF" EXACT [UniProtKB:Q9Y4G8] xref: EMBL:BAA20772.2 xref: UniProtKB:Q9Y4G8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019785 ! RAPGEF2_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003522 ! Rap guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006230 ! Rap GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000403 ! MAPKKK cascade relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction relationship: participates_in CCO:P0001149 ! cAMP-mediated signaling relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0070162 ! RPGF2_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0070163 ! RPGF2_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0070164 ! RPGF2_HUMAN-Phosphoserine935 relationship: transforms_into CCO:B0070165 ! RPGF2_HUMAN-Phosphoserine1022 relationship: transforms_into CCO:B0070166 ! RPGF2_HUMAN-Phosphoserine1116 relationship: transforms_into CCO:B0070167 ! RPGF2_HUMAN-Phosphothreonine1119 [Term] id: CCO:B0059363 name: GPSM3_HUMAN def: "G-protein-signaling modulator 3" [UniProtKB:Q9Y4H4] synonym: "Activator of G-protein signaling 4" EXACT [UniProtKB:Q9Y4H4] synonym: "G18.1b" EXACT [UniProtKB:Q9Y4H4] synonym: "Protein G18" EXACT [UniProtKB:Q9Y4H4] xref: EMBL:AAF67476.1 xref: EMBL:AAH18724.1 xref: EMBL:CAB51288.1 xref: EMBL:CAI17541.1 xref: EMBL:CAI18360.1 xref: EMBL:CAI41816.1 xref: UniProtKB:Q9Y4H4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018045 ! GPSM3_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018461 ! g18_1b-fgfr3 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059364 name: Q9Y4I4_HUMAN def: "Death adaptor molecule RAIDD-2" [UniProtKB:Q9Y4I4] xref: EMBL:AAD38345.1 xref: UniProtKB:Q9Y4I4 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:B0059365 name: M4K5_HUMAN def: "Mitogen-activated protein kinase kinase kinase kinase 5" [UniProtKB:Q9Y4K4] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y4K4] synonym: "KHS" EXACT [UniProtKB:Q9Y4K4] synonym: "Kinase homologous to SPS1/STE20" EXACT [UniProtKB:Q9Y4K4] synonym: "MAPK/ERK kinase kinase kinase 5" EXACT [UniProtKB:Q9Y4K4] synonym: "MEK kinase kinase 5" EXACT [UniProtKB:Q9Y4K4] synonym: "MEKKK 5" EXACT [UniProtKB:Q9Y4K4] xref: EMBL:AAB48435.1 xref: EMBL:AAH36013.1 xref: UniProtKB:Q8IYF6 xref: UniProtKB:Q9Y4K4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018552 ! MAP4K5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015913 ! map4k5-crk-2 physical interaction relationship: participates_in CCO:I0015916 ! map4k5-crk-4 physical interaction relationship: participates_in CCO:I0016010 ! map4k5-crk-1 physical interaction relationship: participates_in CCO:I0016011 ! map4k5-crkl-1 physical interaction relationship: participates_in CCO:I0016108 ! map4k5-grb2-1 physical interaction relationship: participates_in CCO:I0016246 ! map4k5-crk-3 physical interaction relationship: participates_in CCO:P0000767 ! protein kinase cascade relationship: participates_in CCO:P0000774 ! activation of JNK activity relationship: transforms_into CCO:B0067833 ! M4K5_HUMAN-Phosphotyrosine31 relationship: transforms_into CCO:B0067834 ! M4K5_HUMAN-Phosphoserine335 [Term] id: CCO:B0059366 name: KLF12_HUMAN def: "Krueppel-like factor 12" [UniProtKB:Q9Y4X4] synonym: "Transcriptional repressor AP-2rep" EXACT [UniProtKB:Q9Y4X4] xref: EMBL:AAF14863.1 xref: EMBL:AAF29086.1 xref: EMBL:AAH19680.1 xref: EMBL:AAK12082.1 xref: EMBL:CAB46982.1 xref: EMBL:CAH70670.1 xref: EMBL:CAH71998.1 xref: EMBL:CAH74171.1 xref: EMBL:CAI15634.1 xref: UniProtKB:Q5VZM7 xref: UniProtKB:Q9UHZ0 xref: UniProtKB:Q9Y4X4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018410 ! KLF12_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015642 ! ehmt2-klf12 physical interaction relationship: participates_in CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:B0059367 name: Q9Y4Y3_HUMAN def: "E7 protein" [UniProtKB:Q9Y4Y3] xref: EMBL:CAB44707.1 xref: UniProtKB:Q9Y4Y3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021285 ! HPV45 E7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059368 name: HES2_HUMAN def: "Transcription factor HES-2" [UniProtKB:Q9Y543] synonym: "Hairy and enhancer of split 2" EXACT [UniProtKB:Q9Y543] xref: EMBL:AAH12091.1 xref: EMBL:CAB46198.1 xref: EMBL:CAB46199.1 xref: UniProtKB:Q96EN4 xref: UniProtKB:Q9Y542 xref: UniProtKB:Q9Y543 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018118 ! HES2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059369 name: LRP12_HUMAN def: "Low-density lipoprotein receptor-related protein 12 precursor" [UniProtKB:Q9Y561] synonym: "Suppressor of tumorigenicity protein 7" EXACT [UniProtKB:Q9Y561] xref: EMBL:AAD44360.1 xref: EMBL:AAH32109.1 xref: UniProtKB:Q9Y561 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018521 ! LRP12_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001362 ! low-density lipoprotein receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017658 ! st7-gnb2l1-2 physical interaction relationship: participates_in CCO:I0017662 ! st7-madhip-2 physical interaction relationship: participates_in CCO:I0018575 ! st7-actn2-1 physical interaction relationship: participates_in CCO:I0018576 ! st7-ttid-1 physical interaction relationship: participates_in CCO:I0018577 ! st7-snap25bp-1 physical interaction relationship: participates_in CCO:I0019337 ! st7-gnb2l1-1 physical interaction relationship: participates_in CCO:I0019338 ! st7-madhip-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059370 name: RIPK3_HUMAN def: "Receptor-interacting serine/threonine-protein kinase 3" [UniProtKB:Q9Y572] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y572] synonym: "Receptor-interacting protein 3" EXACT [UniProtKB:Q9Y572] synonym: "RIP-3" EXACT [UniProtKB:Q9Y572] synonym: "RIP-like protein kinase 3" EXACT [UniProtKB:Q9Y572] xref: EMBL:AAD39005.1 xref: EMBL:AAH62584.1 xref: EMBL:AAS16359.1 xref: EMBL:AAS75516.1 xref: EMBL:AAS75517.1 xref: EMBL:EAW66021.1 xref: UniProtKB:Q5J795 xref: UniProtKB:Q5J796 xref: UniProtKB:Q6P5Y1 xref: UniProtKB:Q9Y572 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0006013 ! RIPK3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000831 ! induction of apoptosis by extracellular signals [Term] id: CCO:B0059371 name: ASB4_HUMAN def: "Ankyrin repeat and SOCS box protein 4" [UniProtKB:Q9Y574] synonym: "ASB-4" EXACT [UniProtKB:Q9Y574] xref: EMBL:AAB83943.2 xref: EMBL:AAD41896.1 xref: UniProtKB:O14586 xref: UniProtKB:Q9Y574 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017068 ! ASB4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059372 name: ASB3_HUMAN def: "Ankyrin repeat and SOCS box protein 3" [UniProtKB:Q9Y575] synonym: "ASB-3" EXACT [UniProtKB:Q9Y575] xref: EMBL:AAD41895.1 xref: EMBL:AAH06488.1 xref: EMBL:AAH09569.1 xref: EMBL:BAA91455.1 xref: EMBL:BAA91599.1 xref: UniProtKB:Q9NVZ2 xref: UniProtKB:Q9Y575 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017067 ! ASB3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059373 name: ASB1_HUMAN def: "Ankyrin repeat and SOCS box protein 1" [UniProtKB:Q9Y576] synonym: "ASB-1" EXACT [UniProtKB:Q9Y576] xref: EMBL:AAD41894.1 xref: EMBL:AAH14528.1 xref: EMBL:AAX88934.1 xref: EMBL:BAA86460.1 xref: UniProtKB:A6NL50 xref: UniProtKB:Q4ZG29 xref: UniProtKB:Q9ULS4 xref: UniProtKB:Q9Y576 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017065 ! ASB1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0002031 ! negative regulation of cytokine biosynthetic process [Term] id: CCO:B0059374 name: OR1A2_HUMAN def: "Olfactory receptor 1A2" [UniProtKB:Q9Y585] synonym: "Olfactory receptor 17-6" EXACT [UniProtKB:Q9Y585] synonym: "Olfactory receptor OR17-10" EXACT [UniProtKB:Q9Y585] synonym: "OR17-6" EXACT [UniProtKB:Q9Y585] xref: EMBL:AAD39545.1 xref: EMBL:AAH69092.1 xref: EMBL:AAI06734.1 xref: EMBL:AAI06735.1 xref: EMBL:AAK95041.1 xref: EMBL:DAA04640.1 xref: UniProtKB:Q3KPH3 xref: UniProtKB:Q6IFM0 xref: UniProtKB:Q6NTD8 xref: UniProtKB:Q96R86 xref: UniProtKB:Q9Y585 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019058 ! OR1A2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059375 name: ZSC21_HUMAN def: "Zinc finger and SCAN domain-containing protein 21" [UniProtKB:Q9Y5A6] synonym: "Renal carcinoma antigen NY-REN-21" EXACT [UniProtKB:Q9Y5A6] synonym: "Zfp-38" EXACT [UniProtKB:Q9Y5A6] synonym: "Zinc finger protein 38 homolog" EXACT [UniProtKB:Q9Y5A6] xref: EMBL:AAD42866.1 xref: EMBL:AAH47309.1 xref: EMBL:CAB66799.1 xref: UniProtKB:Q9H0B5 xref: UniProtKB:Q9Y5A6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0021003 ! ZSCAN21_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059376 name: GCFC_HUMAN def: "GC-rich sequence DNA-binding factor homolog" [UniProtKB:Q9Y5B6] xref: EMBL:AAD34617.1 xref: EMBL:AAF72944.1 xref: EMBL:AAK68721.1 xref: EMBL:AAK68722.1 xref: EMBL:AAK68723.1 xref: EMBL:AAK68724.1 xref: EMBL:CAC40813.1 xref: EMBL:CAC40814.1 xref: UniProtKB:Q96DU8 xref: UniProtKB:Q9NYQ0 xref: UniProtKB:Q9Y5B6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017892 ! GCFC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002369 ! regulation of transcription relationship: transforms_into CCO:B0066404 ! GCFC_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0066405 ! GCFC_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0066406 ! GCFC_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0066407 ! GCFC_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0066408 ! GCFC_HUMAN-Phosphoserine158 relationship: transforms_into CCO:B0066409 ! GCFC_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0066410 ! GCFC_HUMAN-Phosphoserine262 relationship: transforms_into CCO:B0066411 ! GCFC_HUMAN-Phosphothreonine378 relationship: transforms_into CCO:B0066412 ! GCFC_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0066413 ! GCFC_HUMAN-Phosphoserine557 relationship: transforms_into CCO:B0066414 ! GCFC_HUMAN-Phosphoserine558 [Term] id: CCO:B0059377 name: ANGL3_HUMAN def: "Angiopoietin-related protein 3 precursor" [UniProtKB:Q9Y5C1] synonym: "ANG-5" EXACT [UniProtKB:Q9Y5C1] synonym: "Angiopoietin-5" EXACT [UniProtKB:Q9Y5C1] synonym: "Angiopoietin-like 3" EXACT [UniProtKB:Q9Y5C1] xref: EMBL:AAD34156.1 xref: EMBL:AAH58287.1 xref: EMBL:AAQ88640.1 xref: EMBL:AAS66984.1 xref: UniProtKB:Q9Y5C1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0016967 ! ANGPTL3_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001215 ! phospholipase inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0005862 ! cell surface binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0016012 ! itgav-angptl3-1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000762 ! integrin-mediated signaling pathway relationship: participates_in CCO:P0001258 ! positive regulation of cell migration [Term] id: CCO:B0059378 name: HEY1_HUMAN def: "Hairy/enhancer-of-split related with YRPW motif protein 1" [UniProtKB:Q9Y5J3] synonym: "Cardiovascular helix-loop-helix factor 2" EXACT [UniProtKB:Q9Y5J3] synonym: "CHF-2" EXACT [UniProtKB:Q9Y5J3] synonym: "Hairy and enhancer of split-related protein 1" EXACT [UniProtKB:Q9Y5J3] synonym: "Hairy-related transcription factor 1" EXACT [UniProtKB:Q9Y5J3] synonym: "HES-related repressor protein 1" EXACT [UniProtKB:Q9Y5J3] synonym: "HESR-1" EXACT [UniProtKB:Q9Y5J3] synonym: "hHRT1" EXACT [UniProtKB:Q9Y5J3] xref: EMBL:AAD38967.1 xref: EMBL:AAD51749.1 xref: EMBL:AAF37297.1 xref: EMBL:AAG31156.1 xref: EMBL:AAH01873.1 xref: EMBL:AAV38868.1 xref: EMBL:CAB75715.1 xref: UniProtKB:Q5TZS3 xref: UniProtKB:Q9NYP4 xref: UniProtKB:Q9Y5J3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018126 ! HEY1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000754 ! Notch signaling pathway relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059379 name: HRH3_HUMAN def: "Histamine H3 receptor" [UniProtKB:Q9Y5N1] synonym: "G-protein coupled receptor 97" EXACT [UniProtKB:Q9Y5N1] synonym: "HH3R" EXACT [UniProtKB:Q9Y5N1] xref: EMBL:AAD38151.1 xref: EMBL:AAH96840.1 xref: EMBL:AAK50040.1 xref: EMBL:BAB17030.1 xref: EMBL:BAB20090.1 xref: EMBL:CAC04014.1 xref: EMBL:CAC39434.1 xref: EMBL:CAC51025.1 xref: UniProtKB:Q4QRI7 xref: UniProtKB:Q9GZX2 xref: UniProtKB:Q9H4K8 xref: UniProtKB:Q9Y5N1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018160 ! HRH3_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger [Term] id: CCO:B0059380 name: O51B4_HUMAN def: "Olfactory receptor 51B4" [UniProtKB:Q9Y5P0] synonym: "Odorant receptor HOR5'beta1" EXACT [UniProtKB:Q9Y5P0] xref: EMBL:AAD29426.2 xref: EMBL:AAH69094.1 xref: UniProtKB:Q6NTD7 xref: UniProtKB:Q9Y5P0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018984 ! OR51B4_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059381 name: O51B2_HUMAN def: "Olfactory receptor 51B2" [UniProtKB:Q9Y5P1] synonym: "Odorant receptor HOR5'beta3" EXACT [UniProtKB:Q9Y5P1] xref: EMBL:AAD29425.2 xref: EMBL:AAK94988.1 xref: UniProtKB:Q96RD4 xref: UniProtKB:Q9Y5P1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018983 ! OR51B2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059382 name: HEMK1_HUMAN def: "HemK methyltransferase family member 1" [UniProtKB:Q9Y5R4] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q9Y5R4] synonym: "M.HsaHemKP" EXACT [UniProtKB:Q9Y5R4] xref: EMBL:AAD26417.1 xref: EMBL:AAD51328.1 xref: EMBL:AAH00781.1 xref: UniProtKB:Q9Y5R4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018114 ! HEMK1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001757 ! N-methyltransferase activity relationship: has_function CCO:F0001813 ! protein methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000646 ! DNA methylation [Term] id: CCO:B0059383 name: DMRT2_HUMAN def: "Doublesex- and mab-3-related transcription factor 2" [UniProtKB:Q9Y5R5] synonym: "Doublesex-like 2 protein" EXACT [UniProtKB:Q9Y5R5] synonym: "DSXL-2" EXACT [UniProtKB:Q9Y5R5] xref: EMBL:AAD40475.1 xref: EMBL:AAF86291.1 xref: EMBL:AAF86293.1 xref: EMBL:CAB59891.1 xref: UniProtKB:Q9Y5R5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017588 ! DMRT2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059384 name: DMRT1_HUMAN def: "Doublesex- and mab-3-related transcription factor 1" [UniProtKB:Q9Y5R6] synonym: "DM domain expressed in testis protein 1" EXACT [UniProtKB:Q9Y5R6] xref: EMBL:AAD40474.1 xref: EMBL:AAH40847.1 xref: EMBL:CAB82427.1 xref: EMBL:CAB82851.1 xref: EMBL:CAB99335.1 xref: UniProtKB:Q8IW77 xref: UniProtKB:Q9Y5R6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017587 ! DMRT1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059385 name: MRCKB_HUMAN def: "Serine/threonine-protein kinase MRCK beta" [UniProtKB:Q9Y5S2] synonym: "CDC42-binding protein kinase beta" EXACT [UniProtKB:Q9Y5S2] synonym: "DMPK-like beta" EXACT [UniProtKB:Q9Y5S2] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y5S2] synonym: "MRCK beta" EXACT [UniProtKB:Q9Y5S2] synonym: "Myotonic dystrophy kinase-related CDC42-binding kinase beta" EXACT [UniProtKB:Q9Y5S2] synonym: "Myotonic dystrophy protein kinase-like beta" EXACT [UniProtKB:Q9Y5S2] xref: EMBL:AAD37506.1 xref: EMBL:AAH47871.1 xref: EMBL:ABC67469.1 xref: EMBL:BAA86438.2 xref: UniProtKB:Q2L7A5 xref: UniProtKB:Q86TJ1 xref: UniProtKB:Q9ULU5 xref: UniProtKB:Q9Y5S2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018652 ! CDC42BPB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade relationship: participates_in CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: transforms_into CCO:B0068275 ! MRCKB_HUMAN-Phosphoserine221 relationship: transforms_into CCO:B0068276 ! MRCKB_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0068277 ! MRCKB_HUMAN-Phosphothreonine239 relationship: transforms_into CCO:B0068278 ! MRCKB_HUMAN-Phosphoserine914 relationship: transforms_into CCO:B0068279 ! MRCKB_HUMAN-Phosphotyrosine954 relationship: transforms_into CCO:B0068280 ! MRCKB_HUMAN-Phosphothreonine1196 relationship: transforms_into CCO:B0068281 ! MRCKB_HUMAN-Phosphoserine1690 relationship: transforms_into CCO:B0068282 ! MRCKB_HUMAN-Phosphoserine1693 [Term] id: CCO:B0059386 name: NOX1_HUMAN def: "NADPH oxidase 1" [UniProtKB:Q9Y5S8] synonym: "EC 1.-.-.-" EXACT [UniProtKB:Q9Y5S8] synonym: "Mitogenic oxidase 1" EXACT [UniProtKB:Q9Y5S8] synonym: "MOX1" EXACT [UniProtKB:Q9Y5S8] synonym: "NADH/NADPH mitogenic oxidase subunit P65-MOX" EXACT [UniProtKB:Q9Y5S8] synonym: "NOH-1" EXACT [UniProtKB:Q9Y5S8] synonym: "NOX-1" EXACT [UniProtKB:Q9Y5S8] xref: EMBL:AAD38133.1 xref: EMBL:AAF23232.1 xref: EMBL:AAF23233.1 xref: EMBL:AAF23234.1 xref: EMBL:AAH75014.1 xref: EMBL:AAH75015.1 xref: EMBL:ABC40742.1 xref: EMBL:CAI42336.1 xref: EMBL:CAI42337.1 xref: UniProtKB:O95691 xref: UniProtKB:Q2PP02 xref: UniProtKB:Q9Y5S8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018821 ! NOX1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003063 ! superoxide-generating NADPH oxidase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004338 ! voltage-gated proton channel activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007332 ! Rac GTPase binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_function CCO:F0007987 ! NADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001708 ! NADPH oxidase complex relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: participates_in CCO:P0002523 ! positive regulation of integrin biosynthetic process relationship: participates_in CCO:P0002859 ! positive regulation of smooth muscle cell proliferation [Term] id: CCO:B0059387 name: TNR18_HUMAN def: "Tumor necrosis factor receptor superfamily member 18 precursor" [UniProtKB:Q9Y5U5] synonym: "Activation-inducible TNFR family receptor" EXACT [UniProtKB:Q9Y5U5] synonym: "Glucocorticoid-induced TNFR-related protein" EXACT [UniProtKB:Q9Y5U5] xref: EMBL:AAD19694.1 xref: EMBL:AAD22635.1 xref: EMBL:AAF63506.1 xref: EMBL:AAQ89236.1 xref: EMBL:AAV38339.1 xref: UniProtKB:O95851 xref: UniProtKB:Q9NYJ9 xref: UniProtKB:Q9Y5U5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020314 ! TNFRSF18_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001358 ! tumor necrosis factor receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000671 ! anti-apoptosis relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059388 name: KLF2_HUMAN def: "Krueppel-like factor 2" [UniProtKB:Q9Y5W3] synonym: "Lung krueppel-like factor" EXACT [UniProtKB:Q9Y5W3] xref: EMBL:AAD25076.1 xref: EMBL:AAD55891.1 xref: EMBL:AAF13295.1 xref: EMBL:AAH71983.1 xref: EMBL:ABK41959.1 xref: UniProtKB:Q6IPC4 xref: UniProtKB:Q9UJS5 xref: UniProtKB:Q9UKR6 xref: UniProtKB:Q9Y5W3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018417 ! KLF2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:B0059389 name: WIF1_HUMAN def: "Wnt inhibitory factor 1 precursor" [UniProtKB:Q9Y5W5] synonym: "WIF-1" EXACT [UniProtKB:Q9Y5W5] xref: EMBL:AAD25402.1 xref: EMBL:AAH18037.1 xref: EMBL:AAQ88710.1 xref: UniProtKB:Q6UXI1 xref: UniProtKB:Q8WVG4 xref: UniProtKB:Q9Y5W5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020476 ! WIF1_human relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0059390 name: SNX13_HUMAN def: "Sorting nexin-13" [UniProtKB:Q9Y5W8] synonym: "RGS domain- and PHOX domain-containing protein" EXACT [UniProtKB:Q9Y5W8] synonym: "RGS-PX1" EXACT [UniProtKB:Q9Y5W8] xref: EMBL:AAD27835.1 xref: EMBL:AAH22060.1 xref: EMBL:AAL37728.1 xref: EMBL:BAA34433.1 xref: UniProtKB:O94821 xref: UniProtKB:Q8WVZ2 xref: UniProtKB:Q8WXH8 xref: UniProtKB:Q9Y5W8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019969 ! SNX13_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000886 ! negative regulation of signal transduction relationship: transforms_into CCO:B0070711 ! SNX13_HUMAN-Phosphothreonine359 [Term] id: CCO:B0059391 name: NR2E3_HUMAN def: "Photoreceptor-specific nuclear receptor" [UniProtKB:Q9Y5X4] synonym: "Nuclear receptor subfamily 2 group E member 3" EXACT [UniProtKB:Q9Y5X4] synonym: "Retina-specific nuclear receptor" EXACT [UniProtKB:Q9Y5X4] xref: EMBL:AAD28301.1 xref: EMBL:AAF22227.1 xref: EMBL:CAB82769.1 xref: UniProtKB:Q9UHM4 xref: UniProtKB:Q9Y5X4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018859 ! NR2E3_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: participates_in CCO:P0000708 ! signal transduction relationship: transforms_into CCO:B0068821 ! NR2E3_HUMAN-Phosphothreonine333 [Term] id: CCO:B0059392 name: NPFF2_HUMAN def: "Neuropeptide FF receptor 2" [UniProtKB:Q9Y5X5] synonym: "G-protein coupled receptor 74" EXACT [UniProtKB:Q9Y5X5] synonym: "G-protein coupled receptor HLWAR77" EXACT [UniProtKB:Q9Y5X5] synonym: "Neuropeptide G-protein coupled receptor" EXACT [UniProtKB:Q9Y5X5] xref: EMBL:AAD22047.1 xref: EMBL:AAF87078.1 xref: EMBL:AAG41398.1 xref: EMBL:AAK58513.1 xref: EMBL:AAK94197.1 xref: EMBL:CAC85427.1 xref: UniProtKB:Q96RV1 xref: UniProtKB:Q9NR49 xref: UniProtKB:Q9Y5X5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018833 ! NPFFR2_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001769 ! neuropeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059393 name: GPR44_HUMAN def: "Putative G-protein coupled receptor 44" [UniProtKB:Q9Y5Y4] synonym: "CD294 antigen" EXACT [UniProtKB:Q9Y5Y4] synonym: "Chemoattractant receptor-homologous molecule expressed on Th2 cells" EXACT [UniProtKB:Q9Y5Y4] xref: EMBL:AAD21055.1 xref: EMBL:AAD34539.1 xref: EMBL:AAH96841.1 xref: EMBL:AAR92484.1 xref: EMBL:BAA74518.1 xref: UniProtKB:O94765 xref: UniProtKB:Q4QRI6 xref: UniProtKB:Q9Y5Y4 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018022 ! GPR44_human relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000214 ! prostaglandin J receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001298 ! prostaglandin D receptor activity relationship: has_function CCO:F0001300 ! prostaglandin F receptor activity relationship: has_function CCO:F0001320 ! N-formyl peptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: participates_in CCO:P0001145 ! calcium-mediated signaling relationship: participates_in CCO:P0002533 ! positive regulation of G-protein coupled receptor protein signaling pathway [Term] id: CCO:B0059394 name: BACE2_HUMAN def: "Beta-secretase 2 precursor" [UniProtKB:Q9Y5Z0] synonym: "Asp 1" EXACT [UniProtKB:Q9Y5Z0] synonym: "ASP1" EXACT [UniProtKB:Q9Y5Z0] synonym: "Aspartic-like protease 56 kDa" EXACT [UniProtKB:Q9Y5Z0] synonym: "Aspartyl protease 1" EXACT [UniProtKB:Q9Y5Z0] synonym: "Beta-site APP-cleaving enzyme 2" EXACT [UniProtKB:Q9Y5Z0] synonym: "Down region aspartic protease" EXACT [UniProtKB:Q9Y5Z0] synonym: "EC 3.4.23.45" EXACT [UniProtKB:Q9Y5Z0] synonym: "Memapsin-1" EXACT [UniProtKB:Q9Y5Z0] synonym: "Membrane-associated aspartic protease 1" EXACT [UniProtKB:Q9Y5Z0] xref: EMBL:AAD45240.1 xref: EMBL:AAD45963.1 xref: EMBL:AAF13714.1 xref: EMBL:AAF17078.1 xref: EMBL:AAF26368.1 xref: EMBL:AAF29494.1 xref: EMBL:AAH14453.1 xref: EMBL:AAQ89286.1 xref: EMBL:CAB90458.1 xref: EMBL:CAB90554.1 xref: UniProtKB:Q9UJT6 xref: UniProtKB:Q9Y5Z0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017113 ! BACE2_human relationship: has_function CCO:F0000659 ! aspartic-type endopeptidase activity relationship: has_function CCO:F0000663 ! pepsin A activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0002375 ! aspartic-type signal peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0002133 ! negative regulation of amyloid precursor protein biosynthetic process [Term] id: CCO:B0059395 name: ETV7_HUMAN def: "Transcription factor ETV7" [UniProtKB:Q9Y603] synonym: "ETS-related protein Tel2" EXACT [UniProtKB:Q9Y603] synonym: "Tel-related Ets factor" EXACT [UniProtKB:Q9Y603] synonym: "Transcription factor Tel-2" EXACT [UniProtKB:Q9Y603] xref: EMBL:AAD33989.1 xref: EMBL:AAD43250.1 xref: EMBL:AAD43251.1 xref: EMBL:AAD43252.1 xref: EMBL:AAF25007.3 xref: EMBL:AAF28350.1 xref: EMBL:AAF44742.1 xref: EMBL:AAF44743.1 xref: EMBL:AAH35853.1 xref: EMBL:CAC17012.1 xref: EMBL:CAI21615.1 xref: UniProtKB:Q5R3L4 xref: UniProtKB:Q9NZ65 xref: UniProtKB:Q9NZ66 xref: UniProtKB:Q9NZ68 xref: UniProtKB:Q9NZR8 xref: UniProtKB:Q9UNJ7 xref: UniProtKB:Q9Y5K4 xref: UniProtKB:Q9Y603 xref: UniProtKB:Q9Y604 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017742 ! ETV7_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059396 name: IRAK3_HUMAN def: "Interleukin-1 receptor-associated kinase 3" [UniProtKB:Q9Y616] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y616] synonym: "IL-1 receptor-associated kinase M" EXACT [UniProtKB:Q9Y616] synonym: "IRAK-3" EXACT [UniProtKB:Q9Y616] synonym: "IRAK-M" EXACT [UniProtKB:Q9Y616] xref: EMBL:AAD40879.1 xref: EMBL:AAH57800.1 xref: EMBL:AAH69388.1 xref: UniProtKB:Q9Y616 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018310 ! IRAK3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017989 ! irak3-myd88-ex1 physical interaction relationship: participates_in CCO:I0017992 ! irak3-traf6-ex1 physical interaction relationship: participates_in CCO:I0017997 ! irak3-irak3-ex1 physical interaction relationship: participates_in CCO:I0017999 ! irak1-irak3-ex1 physical interaction relationship: participates_in CCO:I0018001 ! irak2-irak3-ex1 physical interaction relationship: participates_in CCO:I0018002 ! irak3-irak1-ex1 physical interaction relationship: participates_in CCO:I0018003 ! irak3-irak2-ex1 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: participates_in CCO:P0002175 ! regulation of protein complex disassembly [Term] id: CCO:B0059397 name: GPR56_HUMAN def: "G-protein coupled receptor 56 precursor" [UniProtKB:Q9Y653] synonym: "Protein TM7XN1" EXACT [UniProtKB:Q9Y653] xref: EMBL:AAD30545.1 xref: EMBL:AAH08770.1 xref: EMBL:AAP35975.1 xref: EMBL:AAQ88766.1 xref: EMBL:BAC06124.1 xref: EMBL:CAB37294.1 xref: EMBL:EAW82939.1 xref: EMBL:EAW82940.1 xref: UniProtKB:A6NIT7 xref: UniProtKB:A6NJV9 xref: UniProtKB:O95966 xref: UniProtKB:Q8NGB3 xref: UniProtKB:Q96HB4 xref: UniProtKB:Q9Y653 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018026 ! GPR56_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: participates_in CCO:P0000753 ! neuropeptide signaling pathway [Term] id: CCO:B0059398 name: Q9Y656_HUMAN def: "WSB-1 isoform" [UniProtKB:Q9Y656] xref: EMBL:AAD43037.1 xref: UniProtKB:Q9Y656 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059399 name: ARL5A_HUMAN def: "ADP-ribosylation factor-like protein 5A" [UniProtKB:Q9Y689] xref: EMBL:AAD40383.1 xref: EMBL:AAH01254.1 xref: EMBL:AAM12605.1 xref: EMBL:AAP88831.1 xref: EMBL:AAP97188.1 xref: UniProtKB:Q9Y689 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017037 ! ARL5A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0059400 name: MORF4_HUMAN xref: UniProtKB:Q9Y690 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000815 ! cell proliferation [Term] id: CCO:B0059401 name: GMEB1_HUMAN def: "Glucocorticoid modulatory element-binding protein 1" [UniProtKB:Q9Y692] synonym: "DNA-binding protein p96PIF" EXACT [UniProtKB:Q9Y692] synonym: "GMEB-1" EXACT [UniProtKB:Q9Y692] synonym: "Parvovirus initiation factor p96" EXACT [UniProtKB:Q9Y692] synonym: "PIF p96" EXACT [UniProtKB:Q9Y692] xref: EMBL:AAD39355.1 xref: EMBL:AAD51352.1 xref: EMBL:AAG01189.1 xref: EMBL:AAH01473.1 xref: EMBL:BAA91410.1 xref: UniProtKB:Q9NWH1 xref: UniProtKB:Q9UKD0 xref: UniProtKB:Q9Y692 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017938 ! GMEB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0066473 ! GMEB1_HUMAN-Phosphoserine129 [Term] id: CCO:B0059402 name: CLIC4_HUMAN def: "Chloride intracellular channel protein 4" [UniProtKB:Q9Y696] synonym: "Intracellular chloride ion channel protein p64H1" EXACT [UniProtKB:Q9Y696] xref: EMBL:AAD26136.1 xref: EMBL:AAD38446.1 xref: EMBL:AAH12444.1 xref: EMBL:CAB55916.1 xref: UniProtKB:Q9UFW9 xref: UniProtKB:Q9UQJ6 xref: UniProtKB:Q9Y696 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017387 ! CLIC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0001259 ! negative regulation of cell migration relationship: transforms_into CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 [Term] id: CCO:B0059403 name: SAR1B_HUMAN def: "GTP-binding protein SAR1b" [UniProtKB:Q9Y6B6] synonym: "GTBPB" EXACT [UniProtKB:Q9Y6B6] xref: EMBL:AAD40372.1 xref: EMBL:AAH02847.1 xref: EMBL:AAH93034.1 xref: EMBL:AAP97161.1 xref: UniProtKB:Q567T4 xref: UniProtKB:Q9Y6B6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019838 ! SAR1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:B0059404 name: SIRT4_HUMAN def: "NAD-dependent deacetylase sirtuin-4" [UniProtKB:Q9Y6E7] synonym: "EC 3.5.1.-" EXACT [UniProtKB:Q9Y6E7] synonym: "SIR2-like protein 4" EXACT [UniProtKB:Q9Y6E7] xref: EMBL:AAB95634.1 xref: EMBL:AAD40852.1 xref: EMBL:AAI09320.1 xref: EMBL:AAI09321.1 xref: UniProtKB:O43346 xref: UniProtKB:Q32M33 xref: UniProtKB:Q9Y6E7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019914 ! SIRT4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: participates_in CCO:P0000648 ! chromatin silencing relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0070545 ! SIRT4_HUMAN-Phosphoserine255 relationship: transforms_into CCO:B0070546 ! SIRT4_HUMAN-Phosphoserine261 relationship: transforms_into CCO:B0070547 ! SIRT4_HUMAN-Phosphoserine262 [Term] id: CCO:B0059405 name: WNT6_HUMAN def: "Protein Wnt-6 precursor" [UniProtKB:Q9Y6F9] xref: EMBL:AAD41674.1 xref: EMBL:AAG38661.1 xref: EMBL:AAG45154.1 xref: EMBL:AAH04329.1 xref: EMBL:AAP36124.1 xref: EMBL:BAB55603.1 xref: UniProtKB:Q9H1J6 xref: UniProtKB:Q9H238 xref: UniProtKB:Q9Y6F9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020492 ! WNT6_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: participates_in CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway relationship: participates_in CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:B0059406 name: WSB1_HUMAN def: "WD repeat and SOCS box-containing protein 1" [UniProtKB:Q9Y6I7] synonym: "SOCS box-containing WD protein SWiP-1" EXACT [UniProtKB:Q9Y6I7] synonym: "WSB-1" EXACT [UniProtKB:Q9Y6I7] xref: EMBL:AAD20954.2 xref: EMBL:AAD28808.1 xref: EMBL:AAD43036.1 xref: EMBL:AAF17193.1 xref: EMBL:AAF82746.1 xref: EMBL:AAH21110.1 xref: EMBL:CAB53693.1 xref: UniProtKB:Q9NRB1 xref: UniProtKB:Q9UBH9 xref: UniProtKB:Q9UNN6 xref: UniProtKB:Q9Y6I7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020500 ! WSB1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059407 name: CABIN_HUMAN def: "Calcineurin-binding protein cabin-1" [UniProtKB:Q9Y6J0] synonym: "CAIN" EXACT [UniProtKB:Q9Y6J0] synonym: "Calcineurin inhibitor" EXACT [UniProtKB:Q9Y6J0] xref: EMBL:AAD40846.1 xref: EMBL:BAA20788.2 xref: EMBL:CAB62954.1 xref: UniProtKB:Q9Y460 xref: UniProtKB:Q9Y6J0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017202 ! CABIN1_human relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: transforms_into CCO:B0064034 ! CABIN_HUMAN-Phosphothreonine2089 [Term] id: CCO:B0059408 name: SMA5O_HUMAN def: "SMAD5 opposite strand protein" [UniProtKB:Q9Y6J3] synonym: "10.3 kDa proline-rich protein DAMS" EXACT [UniProtKB:Q9Y6J3] xref: EMBL:AAD20804.1 xref: UniProtKB:Q9Y6J3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019937 ! SMAD5OS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000708 ! signal transduction [Term] id: CCO:B0059409 name: STYL1_HUMAN def: "Serine/threonine/tyrosine-interacting-like protein 1" [UniProtKB:Q9Y6J8] synonym: "Dual specificity phosphatase inhibitor MK-STYX" EXACT [UniProtKB:Q9Y6J8] synonym: "Dual specificity protein phosphatase 24" EXACT [UniProtKB:Q9Y6J8] synonym: "Map kinase phosphatase-like protein MK-STYX" EXACT [UniProtKB:Q9Y6J8] xref: EMBL:AAD36983.1 xref: EMBL:AAD53723.1 xref: EMBL:AAD53724.1 xref: EMBL:AAF04111.1 xref: EMBL:AAF04112.1 xref: EMBL:AAF04113.1 xref: EMBL:AAF04114.1 xref: EMBL:AAH24035.1 xref: EMBL:AAS07535.1 xref: UniProtKB:Q9UBP1 xref: UniProtKB:Q9UK06 xref: UniProtKB:Q9UK07 xref: UniProtKB:Q9UKG2 xref: UniProtKB:Q9UKG3 xref: UniProtKB:Q9Y6J8 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020080 ! STYXL1_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059410 name: IF2B2_HUMAN def: "Insulin-like growth factor 2 mRNA-binding protein 2" [UniProtKB:Q9Y6M1] synonym: "Hepatocellular carcinoma autoantigen p62" EXACT [UniProtKB:Q9Y6M1] synonym: "IGF-II mRNA-binding protein 2" EXACT [UniProtKB:Q9Y6M1] synonym: "IGF2 mRNA-binding protein 2" EXACT [UniProtKB:Q9Y6M1] synonym: "IMP-2" EXACT [UniProtKB:Q9Y6M1] synonym: "VICKZ family member 2" EXACT [UniProtKB:Q9Y6M1] xref: EMBL:AAD31596.1 xref: UniProtKB:Q9Y6M1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018221 ! IGF2BP2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006094 ! translation regulator activity relationship: has_function CCO:F0007303 ! mRNA 5'-UTR binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001849 ! cytoskeletal part relationship: participates_in CCO:P0000660 ! regulation of translation relationship: participates_in CCO:P0001135 ! negative regulation of translation relationship: participates_in CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: transforms_into CCO:B0067008 ! IF2B2_HUMAN-Phosphoserine162 relationship: transforms_into CCO:B0067009 ! IF2B2_HUMAN-Phosphoserine164 [Term] id: CCO:B0059411 name: ROBO1_HUMAN def: "Roundabout homolog 1 precursor" [UniProtKB:Q9Y6N7] synonym: "Deleted in U twenty twenty" EXACT [UniProtKB:Q9Y6N7] synonym: "H-Robo-1" EXACT [UniProtKB:Q9Y6N7] xref: EMBL:AAC39575.1 xref: EMBL:AAH01969.1 xref: EMBL:CAD98093.1 xref: UniProtKB:Q7Z300 xref: UniProtKB:Q9BUS7 xref: UniProtKB:Q9Y6N7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019762 ! ROBO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019231 ! robo1-robo2 physical interaction relationship: participates_in CCO:I0020491 ! tubb4-robo1 physical interaction relationship: participates_in CCO:P0002950 ! positive regulation of axonogenesis relationship: transforms_into CCO:B0070124 ! ROBO1_HUMAN-Phosphoserine940 relationship: transforms_into CCO:B0070125 ! ROBO1_HUMAN-Phosphotyrosine1038 relationship: transforms_into CCO:B0070126 ! ROBO1_HUMAN-Phosphoserine1055 relationship: transforms_into CCO:B0070127 ! ROBO1_HUMAN-Phosphotyrosine1073 relationship: transforms_into CCO:B0070128 ! ROBO1_HUMAN-Phosphotyrosine1114 relationship: transforms_into CCO:B0070129 ! ROBO1_HUMAN-Phosphothreonine1240 [Term] id: CCO:B0059412 name: STON1_HUMAN def: "Stonin-1" [UniProtKB:Q9Y6Q2] synonym: "Stoned B-like factor" EXACT [UniProtKB:Q9Y6Q2] xref: EMBL:AAD39617.1 xref: EMBL:AAK11719.1 xref: EMBL:AAK57559.1 xref: UniProtKB:Q96JE3 xref: UniProtKB:Q9BYX3 xref: UniProtKB:Q9Y6Q2 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020072 ! STON1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: participates_in CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:B0059413 name: TNR11_HUMAN def: "Tumor necrosis factor receptor superfamily member 11A precursor" [UniProtKB:Q9Y6Q6] synonym: "CD265 antigen" EXACT [UniProtKB:Q9Y6Q6] synonym: "ODFR" EXACT [UniProtKB:Q9Y6Q6] synonym: "Osteoclast differentiation factor receptor" EXACT [UniProtKB:Q9Y6Q6] synonym: "Receptor activator of NF-KB" EXACT [UniProtKB:Q9Y6Q6] xref: EMBL:AAB86809.1 xref: UniProtKB:Q9Y6Q6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020310 ! TNFRSF11A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015927 ! rank-traf2 physical interaction relationship: participates_in CCO:I0015928 ! rank-traf5 physical interaction relationship: participates_in CCO:I0015929 ! rank-traf6 physical interaction relationship: participates_in CCO:P0000708 ! signal transduction relationship: participates_in CCO:P0000816 ! positive regulation of cell proliferation relationship: transforms_into CCO:B0071442 ! TNR11_HUMAN-Phosphoserine463 [Term] id: CCO:B0059414 name: NUMBL_HUMAN def: "Numb-like protein" [UniProtKB:Q9Y6R0] synonym: "Numb-R" EXACT [UniProtKB:Q9Y6R0] xref: EMBL:AAD01549.1 xref: EMBL:AAP88809.1 xref: UniProtKB:Q7Z4J9 xref: UniProtKB:Q9Y6R0 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018889 ! NUMBL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016159 ! a2bp1-numbl physical interaction relationship: participates_in CCO:I0017546 ! numbl-a2bp1 physical interaction relationship: participates_in CCO:I0017563 ! numbl-atxn1 physical interaction relationship: participates_in CCO:P0000793 ! neuroblast proliferation relationship: transforms_into CCO:B0068927 ! NUMBL_HUMAN-Phosphoserine263 relationship: transforms_into CCO:B0068928 ! NUMBL_HUMAN-Phosphothreonine268 relationship: transforms_into CCO:B0068929 ! NUMBL_HUMAN-Phosphothreonine279 relationship: transforms_into CCO:B0068930 ! NUMBL_HUMAN-Phosphoserine411 [Term] id: CCO:B0059415 name: Z780B_HUMAN def: "Zinc finger protein 780B" [UniProtKB:Q9Y6R6] synonym: "Zinc finger protein 779" EXACT [UniProtKB:Q9Y6R6] xref: EMBL:AAD39268.1 xref: UniProtKB:Q9Y6R6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020539 ! ZNF780B_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0059416 name: Q9Y6T0_HUMAN def: "Similarity by BLASTN to AF063018" [UniProtKB:Q9Y6T0] xref: EMBL:AAD30180.1 xref: UniProtKB:Q9Y6T0 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:P0002369 ! regulation of transcription [Term] id: CCO:B0059417 name: DGKB_HUMAN def: "Diacylglycerol kinase beta" [UniProtKB:Q9Y6T7] synonym: "90 kDa diacylglycerol kinase" EXACT [UniProtKB:Q9Y6T7] synonym: "DAG kinase beta" EXACT [UniProtKB:Q9Y6T7] synonym: "DGK-beta" EXACT [UniProtKB:Q9Y6T7] synonym: "Diglyceride kinase beta" EXACT [UniProtKB:Q9Y6T7] synonym: "EC 2.7.1.107" EXACT [UniProtKB:Q9Y6T7] xref: EMBL:AAC25525.1 xref: EMBL:AAI05006.1 xref: EMBL:AAP21868.1 xref: EMBL:AAP22362.1 xref: EMBL:AAS07495.1 xref: EMBL:AAS07533.1 xref: EMBL:BAA34438.1 xref: EMBL:CAC09945.1 xref: UniProtKB:A8MXU2 xref: UniProtKB:O75241 xref: UniProtKB:Q2M377 xref: UniProtKB:Q75MF9 xref: UniProtKB:Q75MU7 xref: UniProtKB:Q86UI5 xref: UniProtKB:Q86UM9 xref: UniProtKB:Q9UQ29 xref: UniProtKB:Q9Y6T7 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017565 ! DGKB_human relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:P0000740 ! activation of protein kinase C activity relationship: participates_in CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:B0059418 name: WASF2_HUMAN def: "Wiskott-Aldrich syndrome protein family member 2" [UniProtKB:Q9Y6W5] synonym: "Protein WAVE-2" EXACT [UniProtKB:Q9Y6W5] synonym: "Verprolin homology domain-containing protein 2" EXACT [UniProtKB:Q9Y6W5] synonym: "WASP family protein member 2" EXACT [UniProtKB:Q9Y6W5] xref: EMBL:AAH40943.1 xref: EMBL:BAA81795.1 xref: EMBL:CAC18518.1 xref: UniProtKB:O60794 xref: UniProtKB:Q9UDY7 xref: UniProtKB:Q9Y6W5 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0020469 ! WASF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: transforms_into CCO:B0071823 ! WASF2_HUMAN-Phosphoserine482 relationship: transforms_into CCO:B0071824 ! WASF2_HUMAN-Phosphoserine484 relationship: transforms_into CCO:B0071825 ! WASF2_HUMAN-Phosphoserine488 relationship: transforms_into CCO:B0071826 ! WASF2_HUMAN-Phosphoserine489 [Term] id: CCO:B0059419 name: DUS10_HUMAN def: "Dual specificity protein phosphatase 10" [UniProtKB:Q9Y6W6] synonym: "EC 3.1.3.16" EXACT [UniProtKB:Q9Y6W6] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q9Y6W6] synonym: "MAP kinase phosphatase 5" EXACT [UniProtKB:Q9Y6W6] synonym: "Mitogen-activated protein kinase phosphatase 5" EXACT [UniProtKB:Q9Y6W6] synonym: "MKP-5" EXACT [UniProtKB:Q9Y6W6] xref: EMBL:AAD51857.1 xref: EMBL:AAH31405.1 xref: EMBL:AAH63826.1 xref: EMBL:BAA81668.1 xref: EMBL:CAH71120.1 xref: UniProtKB:Q6GSI4 xref: UniProtKB:Q9Y6W6 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017632 ! DUSP10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000772 ! JNK cascade relationship: transforms_into CCO:B0064904 ! DUS10_HUMAN-Phosphoserine4 [Term] id: CCO:B0059420 name: CMTA1_HUMAN def: "Calmodulin-binding transcription activator 1" [UniProtKB:Q9Y6Y1] xref: EMBL:BAA74856.3 xref: EMBL:CAH72347.1 xref: EMBL:CAH72663.1 xref: EMBL:CAI17064.1 xref: EMBL:CAI20961.1 xref: EMBL:CAI21433.1 xref: EMBL:CAI21596.1 xref: EMBL:CAI21790.1 xref: UniProtKB:Q5VUE1 xref: UniProtKB:Q9Y6Y1 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0017395 ! CAMTA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: transforms_into CCO:B0064402 ! CMTA1_HUMAN-Phosphotyrosine117 [Term] id: CCO:B0059421 name: Q9Y6Y5_HUMAN xref: UniProtKB:Q9Y6Y5 is_a: CCO:B0000000 ! core cell cycle protein relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059422 name: Q9Y6Y6_HUMAN xref: UniProtKB:Q9Y6Y6 is_a: CCO:B0000000 ! core cell cycle protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:P0001584 ! regulation of Rab GTPase activity [Term] id: CCO:B0059423 name: LY96_HUMAN def: "Lymphocyte antigen 96 precursor" [UniProtKB:Q9Y6Y9] synonym: "ESOP-1" EXACT [UniProtKB:Q9Y6Y9] synonym: "Protein MD-2" EXACT [UniProtKB:Q9Y6Y9] xref: EMBL:AAF89635.1 xref: EMBL:AAH20690.1 xref: EMBL:BAA78717.1 xref: UniProtKB:Q9Y6Y9 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0018534 ! LY96_human relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:P0000709 ! cell surface receptor linked signal transduction relationship: participates_in CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:B0061983 name: RFX6_HUMAN def: "DNA-binding protein RFX6" [UniProtKB:Q8HWS3] synonym: "Regulatory factor X 6" EXACT [UniProtKB:Q8HWS3] synonym: "Regulatory factor X domain-containing protein 1" EXACT [UniProtKB:Q8HWS3] xref: EMBL:AAH39248.1 xref: EMBL:CAI23444.2 xref: EMBL:EAW48213.1 xref: UniProtKB:Q5T6B3 xref: UniProtKB:Q8HWS3 is_a: CCO:B0000000 ! core cell cycle protein relationship: encoded_by CCO:G0019688 ! RFX6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0005784 ! ccnk-rfxdc1 physical interaction relationship: participates_in CCO:I0015277 ! rfx2-rfxdc1 physical interaction relationship: participates_in CCO:I0015307 ! rfxdc1-ss18l1 physical interaction relationship: participates_in CCO:I0015311 ! dtx2-rfxdc1 physical interaction relationship: participates_in CCO:I0015510 ! lmo3-rfxdc1 physical interaction relationship: participates_in CCO:I0015759 ! rfx3-rfxdc1 physical interaction relationship: participates_in CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:B0061984 name: P121A_HUMAN def: "Nuclear envelope pore membrane protein POM 121" [UniProtKB:Q96HA1] synonym: "Nuclear envelope pore membrane protein POM 121A" EXACT [UniProtKB:Q96HA1] synonym: "Pore membrane protein of 121 kDa" EXACT [UniProtKB:Q96HA1] xref: EMBL:AAH01518.2 xref: EMBL:AAH08794.1 xref: EMBL:BAA31593.2 xref: EMBL:BAB14097.1 xref: EMBL:BAF80887.1 xref: EMBL:BAF85237.1 xref: EMBL:CAB45713.1 xref: EMBL:CAD28472.1 xref: UniProtKB:A6NFS9 xref: UniProtKB:A8CDT4 xref: UniProtKB:A8K933 xref: UniProtKB:O75115 xref: UniProtKB:Q96DI0 xref: UniProtKB:Q96HA1 xref: UniProtKB:Q9H9X1 xref: UniProtKB:Q9Y2N3 xref: UniProtKB:Q9Y4S7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006038 ! POM121_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0005821 ! c10orf3-pom121 physical interaction relationship: participates_in CCO:I0015077 ! pom121-trip6 physical interaction relationship: participates_in CCO:I0015231 ! pom121-trim23 physical interaction relationship: participates_in CCO:I0015670 ! nfkbia-pom121 physical interaction relationship: participates_in CCO:I0015789 ! lpxn-pom121 physical interaction [Term] id: CCO:B0061985 name: JPH1_HUMAN def: "Junctophilin-1" [UniProtKB:Q9HDC5] synonym: "JP-1" EXACT [UniProtKB:Q9HDC5] synonym: "Junctophilin type 1" EXACT [UniProtKB:Q9HDC5] xref: EMBL:BAB11986.1 xref: UniProtKB:Q9HDC5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018368 ! JPH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008962 ! smad3-sry-3 physical interaction relationship: transforms_into CCO:B0067222 ! JPH1_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0067223 ! JPH1_HUMAN-Phosphoserine216 relationship: transforms_into CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0067225 ! JPH1_HUMAN-Phosphothreonine448 relationship: transforms_into CCO:B0067226 ! JPH1_HUMAN-Phosphoserine452 relationship: transforms_into CCO:B0067227 ! JPH1_HUMAN-Phosphothreonine461 relationship: transforms_into CCO:B0067228 ! JPH1_HUMAN-Phosphoserine465 relationship: transforms_into CCO:B0067229 ! JPH1_HUMAN-Phosphoserine469 [Term] id: CCO:B0061986 name: FOX1A_HUMAN def: "Fox-1 homolog A" [UniProtKB:Q9NWB1] synonym: "Ataxin-2-binding protein 1" EXACT [UniProtKB:Q9NWB1] synonym: "Hexaribonucleotide-binding protein 1" EXACT [UniProtKB:Q9NWB1] xref: EMBL:AAF78291.1 xref: EMBL:AAI13692.1 xref: EMBL:AAL71904.1 xref: EMBL:AAL83405.1 xref: EMBL:AAL83406.1 xref: EMBL:AAL83407.1 xref: EMBL:AAL83408.1 xref: EMBL:AAL83409.1 xref: EMBL:AAP41925.1 xref: EMBL:BAA91472.1 xref: UniProtKB:Q7Z7I7 xref: UniProtKB:Q8TAE3 xref: UniProtKB:Q8TAF2 xref: UniProtKB:Q8WYB2 xref: UniProtKB:Q9NS20 xref: UniProtKB:Q9NWB1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006424 ! FOX1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: participates_in CCO:I0006644 ! lzts2-a2bp1 physical interaction relationship: participates_in CCO:I0008701 ! a2bp1-psmf1 physical interaction relationship: participates_in CCO:I0008766 ! psmf1-a2bp1 physical interaction relationship: participates_in CCO:I0016159 ! a2bp1-numbl physical interaction relationship: participates_in CCO:I0016177 ! a2bp1-atxn1 physical interaction relationship: participates_in CCO:I0016178 ! a2bp1-rbm9 physical interaction relationship: participates_in CCO:I0017543 ! dvl2-a2bp1 physical interaction relationship: participates_in CCO:I0017544 ! hnrpf-a2bp1 physical interaction relationship: participates_in CCO:I0017545 ! kifap3-a2bp1 physical interaction relationship: participates_in CCO:I0017546 ! numbl-a2bp1 physical interaction relationship: participates_in CCO:I0018904 ! a2bp1-atxn1-1 physical interaction relationship: participates_in CCO:I0018905 ! a2bp1-atxn2 physical interaction relationship: participates_in CCO:I0018906 ! a2bp1-lw_1 physical interaction relationship: participates_in CCO:I0018907 ! a2bp1-maged1 physical interaction relationship: participates_in CCO:I0018908 ! a2bp1-rbm9-1 physical interaction [Term] id: CCO:B0061987 name: MRLC3_HUMAN def: "Myosin regulatory light chain MRLC3" [UniProtKB:P19105] synonym: "MLC-2B" EXACT [UniProtKB:P19105] synonym: "Myosin regulatory light chain 2, nonsarcomeric" EXACT [UniProtKB:P19105] synonym: "Myosin RLC" EXACT [UniProtKB:P19105] xref: EMBL:AAH16372.1 xref: EMBL:AAH31972.1 xref: EMBL:AAH32748.1 xref: EMBL:CAA38201.1 xref: UniProtKB:P19105 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018660 ! MRLC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007068 ! lrpprc-eif3s8-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016445 ! chuk-mlcb physical interaction relationship: participates_in CCO:I0016486 ! ikbke-mlcb physical interaction relationship: participates_in CCO:I0016564 ! ikbkg-mlcb physical interaction relationship: participates_in CCO:I0016766 ! map3k3-mlcb physical interaction relationship: participates_in CCO:I0017035 ! tnfrsf1a-mlcb physical interaction relationship: participates_in CCO:I0018070 ! cdc42bpa-mlcb-1 phosphorylation relationship: transforms_into CCO:B0068289 ! MRLC3_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0068290 ! MRLC3_HUMAN-Phosphothreonine18 relationship: transforms_into CCO:B0068291 ! MRLC3_HUMAN-Phosphoserine19 [Term] id: CCO:B0061988 name: IL12A_HUMAN def: "Interleukin-12 subunit alpha precursor" [UniProtKB:P29459] synonym: "CLMF p35" EXACT [UniProtKB:P29459] synonym: "Cytotoxic lymphocyte maturation factor 35 kDa subunit" EXACT [UniProtKB:P29459] synonym: "IL-12 subunit p35" EXACT [UniProtKB:P29459] synonym: "IL-12A" EXACT [UniProtKB:P29459] synonym: "NK cell stimulatory factor chain 1" EXACT [UniProtKB:P29459] synonym: "NKSF1" EXACT [UniProtKB:P29459] xref: EMBL:AAA35694.1 xref: EMBL:AAA59937.1 xref: EMBL:AAK84425.1 xref: UniProtKB:P29459 xref: UniProtKB:Q96QZ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018249 ! IL12A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008981 ! il12a-il12b-1 direct interaction [Term] id: CCO:B0061989 name: IN80E_HUMAN def: "INO80 complex subunit E" [UniProtKB:Q8NBZ0] synonym: "Coiled-coil domain-containing protein 95" EXACT [UniProtKB:Q8NBZ0] xref: EMBL:AAH47712.1 xref: EMBL:BAC11424.1 xref: UniProtKB:Q8NBZ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018281 ! INO80E_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007778 ! fj90652-ruvbl-1 physical interaction [Term] id: CCO:B0061990 name: IN80B_HUMAN def: "INO80 complex subunit B" [UniProtKB:Q9C086] synonym: "High mobility group AT-hook 1-like 4" EXACT [UniProtKB:Q9C086] synonym: "PAP-1-associated protein 1" EXACT [UniProtKB:Q9C086] synonym: "PAPA-1" EXACT [UniProtKB:Q9C086] synonym: "Zinc finger HIT domain-containing protein 4" EXACT [UniProtKB:Q9C086] xref: EMBL:AAH50666.1 xref: EMBL:AAH64425.1 xref: EMBL:BAB21111.1 xref: UniProtKB:Q9C086 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018279 ! INO80B_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: participates_in CCO:I0007774 ! znhit4-ruvbl-1 physical interaction relationship: participates_in CCO:I0020024 ! znhit4-cd81 physical interaction relationship: participates_in CCO:I0020573 ! znhit4-rxrip110 physical interaction relationship: transforms_into CCO:B0067089 ! IN80B_HUMAN-Phosphoserine84 relationship: transforms_into CCO:B0067090 ! IN80B_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0067091 ! IN80B_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0067092 ! IN80B_HUMAN-Phosphoserine119 [Term] id: CCO:B0061991 name: INO80_HUMAN def: "Putative DNA helicase INO80 complex homolog 1" [UniProtKB:Q9ULG1] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9ULG1] synonym: "hINO80" EXACT [UniProtKB:Q9ULG1] xref: EMBL:BAA86573.1 xref: EMBL:CAB70675.1 xref: UniProtKB:Q9NTG6 xref: UniProtKB:Q9ULG1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018287 ! INO80_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007770 ! ruvbl1-ruvbl2 physical interaction relationship: participates_in CCO:I0007771 ! ruvbl2-ruvbl1 physical interaction relationship: transforms_into CCO:B0067116 ! INO80_HUMAN-Phosphoserine1490 relationship: transforms_into CCO:B0067117 ! INO80_HUMAN-Phosphoserine1512 relationship: transforms_into CCO:B0067118 ! INO80_HUMAN-Phosphoserine1516 relationship: transforms_into CCO:B0067119 ! INO80_HUMAN-Phosphothreonine1550 [Term] id: CCO:B0061992 name: IN80D_HUMAN def: "INO80 complex subunit D" [UniProtKB:Q53TQ3] xref: EMBL:AAH04193.2 xref: EMBL:AAH11687.1 xref: EMBL:AAH17290.2 xref: EMBL:AAX93069.1 xref: EMBL:BAA91079.1 xref: EMBL:BAG53330.1 xref: UniProtKB:B3KU68 xref: UniProtKB:Q53TQ3 xref: UniProtKB:Q6PJC6 xref: UniProtKB:Q6PJU1 xref: UniProtKB:Q6PKA1 xref: UniProtKB:Q9NXD5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018280 ! INO80D_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007779 ! flj20309-ruvbl-2 physical interaction [Term] id: CCO:B0061993 name: CG064_HUMAN def: "Uncharacterized protein C7orf64" [UniProtKB:Q5RL73] xref: EMBL:AAH33561.1 xref: EMBL:AAH44570.1 xref: EMBL:AAI04866.1 xref: EMBL:AAI04868.1 xref: EMBL:BAB70806.1 xref: EMBL:CAI45942.1 xref: EMBL:EAL24148.1 xref: EMBL:EAW76839.1 xref: UniProtKB:Q5H9T2 xref: UniProtKB:Q5RL73 xref: UniProtKB:Q8IYW7 xref: UniProtKB:Q96NS0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0017341 ! C7orf64_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0008082 ! cdkn2c-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0008238 ! smpd3-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0008269 ! mnat1-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0008273 ! mphosph6-dkfzp564o05 physical interaction relationship: participates_in CCO:I0019571 ! trib3-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019577 ! cdk5rap2-dkfzp564o05 physical interaction relationship: participates_in CCO:I0019618 ! serpinb9-dkfzp564o05 physical interaction relationship: participates_in CCO:I0019639 ! znf24-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019740 ! hspb1-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019810 ! rfc5-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019815 ! rpa2-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019845 ! taf9-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019858 ! tk1-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0019976 ! dnmt2-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020058 ! mafg-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020073 ! mllt3-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020093 ! np-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020121 ! ppp1r8-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020140 ! rab27a-dkfzp564o0523 physical interaction relationship: participates_in CCO:I0020203 ! tnfsf10-dkfzp564o052 physical interaction relationship: participates_in CCO:I0020338 ! id2-dkfzp564o0523 physical interaction [Term] id: CCO:B0061994 name: F173A_HUMAN def: "Protein FAM173A" [UniProtKB:Q9BQD7] xref: EMBL:AAH01181.1 xref: EMBL:AAH02624.1 xref: EMBL:AAK61248.1 xref: UniProtKB:Q9BQD7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0017753 ! FAM173A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008265 ! c16orf24-tp53 physical interaction relationship: participates_in CCO:I0019766 ! c16orf24-htatip physical interaction relationship: participates_in CCO:I0020068 ! c16orf24-pfn2 physical interaction relationship: participates_in CCO:I0020069 ! c16orf24-sh3gl3 physical interaction [Term] id: CCO:B0062767 name: RWD2B_HUMAN def: "RWD domain-containing protein 2B" [UniProtKB:P57060] xref: EMBL:AAH12546.1 xref: EMBL:AAH17912.1 xref: EMBL:AAK14918.1 xref: EMBL:BAA90913.1 xref: EMBL:CAB88085.1 xref: EMBL:CAB90431.1 xref: UniProtKB:P57060 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022621 ! RWDD2B_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0014958 ! c21orf6-gadd45g physical interaction [Term] id: CCO:B0062768 name: PDC10_HUMAN def: "Programmed cell death protein 10" [UniProtKB:Q9BUL8] synonym: "Cerebral cavernous malformations 3 protein" EXACT [UniProtKB:Q9BUL8] synonym: "TF-1 cell apoptosis-related protein 15" EXACT [UniProtKB:Q9BUL8] xref: EMBL:AAB72225.1 xref: EMBL:AAH02506.1 xref: EMBL:AAH16353.1 xref: EMBL:CAG33388.1 xref: UniProtKB:O14811 xref: UniProtKB:Q9BUL8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022493 ! PDCD10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014960 ! pdcd10-stk24 physical interaction relationship: participates_in CCO:I0015528 ! pdcd10-stk25 physical interaction [Term] id: CCO:B0062769 name: EXOC7_HUMAN def: "Exocyst complex component 7" [UniProtKB:Q9UPT5] synonym: "Exocyst complex component Exo70" EXACT [UniProtKB:Q9UPT5] xref: EMBL:AAH11045.1 xref: EMBL:AAH18466.1 xref: EMBL:BAA83019.1 xref: EMBL:BAB14026.1 xref: EMBL:BAB14095.1 xref: EMBL:BAB14694.1 xref: EMBL:CAD38992.2 xref: UniProtKB:Q8ND93 xref: UniProtKB:Q8WV91 xref: UniProtKB:Q96FF0 xref: UniProtKB:Q9H8C3 xref: UniProtKB:Q9H9X3 xref: UniProtKB:Q9HA32 xref: UniProtKB:Q9UPT5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022231 ! EXOC7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000024 ! exocyst relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002178 ! centriolar satellite relationship: participates_in CCO:I0014961 ! exoc7-hgs physical interaction relationship: participates_in CCO:I0015819 ! exoc7-prp19 physical interaction relationship: transforms_into CCO:B0066033 ! EXOC7_HUMAN-Phosphoserine250 [Term] id: CCO:B0062770 name: ZDHC3_HUMAN def: "Palmitoyltransferase ZDHHC3" [UniProtKB:Q9NYG2] synonym: "DHHC-3" EXACT [UniProtKB:Q9NYG2] synonym: "DHHC1 protein" EXACT [UniProtKB:Q9NYG2] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q9NYG2] synonym: "Zinc finger DHHC domain-containing protein 3" EXACT [UniProtKB:Q9NYG2] synonym: "Zinc finger protein 373" EXACT [UniProtKB:Q9NYG2] xref: EMBL:AAF63570.1 xref: EMBL:AAH15467.1 xref: EMBL:AAL34547.1 xref: EMBL:AAV83779.1 xref: UniProtKB:Q53A17 xref: UniProtKB:Q96BL0 xref: UniProtKB:Q9NYG2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022799 ! ZDHHC3_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0014963 ! ewsr1-zdhhc3 physical interaction [Term] id: CCO:B0062771 name: FBX28_HUMAN def: "F-box only protein 28" [UniProtKB:Q9NVF7] xref: EMBL:AAH31576.1 xref: EMBL:BAA32327.1 xref: EMBL:BAA91795.1 xref: EMBL:CAH70934.1 xref: UniProtKB:O75070 xref: UniProtKB:Q9NVF7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022253 ! FBXO28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014964 ! fbxo28-traf2 physical interaction relationship: transforms_into CCO:B0066146 ! FBX28_HUMAN-Phosphoserine235 relationship: transforms_into CCO:B0066147 ! FBX28_HUMAN-Phosphoserine344 [Term] id: CCO:B0062772 name: DD19A_HUMAN def: "ATP-dependent RNA helicase DDX19A" [UniProtKB:Q9NUU7] synonym: "DDX19-like protein" EXACT [UniProtKB:Q9NUU7] synonym: "DEAD box protein 19A" EXACT [UniProtKB:Q9NUU7] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9NUU7] xref: EMBL:AAH05162.1 xref: EMBL:AAH06544.1 xref: EMBL:BAA92022.1 xref: EMBL:BAD96982.1 xref: EMBL:CAH10622.1 xref: UniProtKB:Q53FM0 xref: UniProtKB:Q9NUU7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022173 ! DDX19A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0014965 ! ddx19a-mdfi physical interaction [Term] id: CCO:B0062773 name: ITM2C_HUMAN def: "Integral membrane protein 2C" [UniProtKB:Q9NQX7] synonym: "Cerebral protein 14" EXACT [UniProtKB:Q9NQX7] synonym: "Transmembrane protein BRI3" EXACT [UniProtKB:Q9NQX7] xref: EMBL:AAF89492.1 xref: EMBL:AAG44792.1 xref: EMBL:AAH02424.1 xref: EMBL:AAH25742.1 xref: EMBL:AAH50668.1 xref: EMBL:AAH98563.1 xref: EMBL:AAL15434.1 xref: EMBL:BAB46927.1 xref: EMBL:BAC03562.1 xref: EMBL:BAC11570.1 xref: EMBL:BAD96417.1 xref: EMBL:CAB66538.1 xref: EMBL:CAD28460.1 xref: EMBL:CAG33489.1 xref: UniProtKB:Q4G0A8 xref: UniProtKB:Q53H84 xref: UniProtKB:Q6IAE7 xref: UniProtKB:Q86VK5 xref: UniProtKB:Q8N288 xref: UniProtKB:Q8TAW0 xref: UniProtKB:Q9BUP8 xref: UniProtKB:Q9NQX7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022344 ! ITM2C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0014970 ! itm2c-rnf7 physical interaction relationship: transforms_into CCO:B0067164 ! ITM2C_HUMAN-Phosphothreonine37 [Term] id: CCO:B0062774 name: S22AO_HUMAN def: "Solute carrier family 22 member 24" [UniProtKB:Q8N4F4] xref: EMBL:AAH34394.1 xref: UniProtKB:Q8N4F4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022629 ! SLC22A24_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0014972 ! ewsr1-mgc34821 physical interaction [Term] id: CCO:B0062775 name: TESC_HUMAN def: "Tescalcin" [UniProtKB:Q96BS2] synonym: "TSC" EXACT [UniProtKB:Q96BS2] xref: EMBL:AAH15221.1 xref: EMBL:AAL35615.1 xref: EMBL:BAA91288.1 xref: EMBL:EAW98101.1 xref: UniProtKB:Q96BS2 xref: UniProtKB:Q9NWT9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022705 ! TESC_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004135 ! phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000935 ! lamellipodium relationship: participates_in CCO:I0014973 ! hmg20a-tesc physical interaction relationship: participates_in CCO:I0019433 ! tesc-hmg20a physical interaction [Term] id: CCO:B0062776 name: DYDC1_HUMAN def: "DPY30 domain-containing protein 1" [UniProtKB:Q8WWB3] xref: EMBL:AAH19250.1 xref: EMBL:AAQ84766.1 xref: EMBL:BAC86339.1 xref: EMBL:CAI13699.1 xref: EMBL:CAI13701.1 xref: EMBL:CAI13702.1 xref: UniProtKB:Q5QP03 xref: UniProtKB:Q5QP04 xref: UniProtKB:Q6WNP4 xref: UniProtKB:Q6ZU87 xref: UniProtKB:Q8WWB3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022199 ! DYDC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014974 ! dydc1-nme5 physical interaction [Term] id: CCO:B0062777 name: RBM41_HUMAN def: "RNA-binding protein 41" [UniProtKB:Q96IZ5] synonym: "RNA-binding motif protein 41" EXACT [UniProtKB:Q96IZ5] xref: EMBL:AAH06986.1 xref: EMBL:BAA91957.1 xref: EMBL:BAB14660.1 xref: EMBL:CAC19636.1 xref: EMBL:CAI41564.1 xref: UniProtKB:Q5JSN7 xref: UniProtKB:Q5JSN8 xref: UniProtKB:Q96IZ5 xref: UniProtKB:Q9H8F7 xref: UniProtKB:Q9NV04 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022559 ! RBM41_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014979 ! flj11016-hnrpk physical interaction relationship: transforms_into CCO:B0069821 ! RBM41_HUMAN-Phosphoserine232 [Term] id: CCO:B0062778 name: ADPPT_HUMAN def: "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase" [UniProtKB:Q9NRN7] synonym: "4'-phosphopantetheinyl transferase" EXACT [UniProtKB:Q9NRN7] synonym: "AASD-PPT" EXACT [UniProtKB:Q9NRN7] synonym: "Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase" EXACT [UniProtKB:Q9NRN7] synonym: "EC 2.7.8.-" EXACT [UniProtKB:Q9NRN7] synonym: "LYS5 ortholog" EXACT [UniProtKB:Q9NRN7] xref: EMBL:AAD34075.1 xref: EMBL:AAF36143.1 xref: EMBL:AAF86879.1 xref: EMBL:AAG30872.1 xref: EMBL:AAG49439.1 xref: EMBL:AAH15470.1 xref: EMBL:AAH16728.1 xref: EMBL:CAB43257.1 xref: UniProtKB:Q9C068 xref: UniProtKB:Q9NRN7 xref: UniProtKB:Q9P0Q3 xref: UniProtKB:Q9UG80 xref: UniProtKB:Q9Y389 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022025 ! AASDHPPT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0014985 ! aasdhppt-mdfi physical interaction relationship: participates_in CCO:I0015268 ! aasdhppt-traf2 physical interaction relationship: transforms_into CCO:B0065435 ! ADPPT_HUMAN-Phosphoserine258 [Term] id: CCO:B0062779 name: PHP14_HUMAN def: "14 kDa phosphohistidine phosphatase" [UniProtKB:Q9NRX4] synonym: "EC 3.1.3.-" EXACT [UniProtKB:Q9NRX4] synonym: "Phosphohistidine phosphatase 1" EXACT [UniProtKB:Q9NRX4] synonym: "Protein janus-A homolog" EXACT [UniProtKB:Q9NRX4] xref: EMBL:AAF80759.1 xref: EMBL:AAG01156.1 xref: EMBL:AAH24648.1 xref: EMBL:AAN52504.1 xref: EMBL:CAB66579.1 xref: UniProtKB:Q9H0Y3 xref: UniProtKB:Q9NRX4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022512 ! PHPT1_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0002302 ! phosphohistidine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0014989 ! dnmt3l-phpt1 physical interaction relationship: participates_in CCO:I0018978 ! atxn1-phpt1 physical interaction relationship: participates_in CCO:I0019101 ! atxn1-phpt1-1 physical interaction relationship: transforms_into CCO:B0069289 ! PHP14_HUMAN-Phosphotyrosine93 [Term] id: CCO:B0062780 name: NUP54_HUMAN def: "Nucleoporin p54" [UniProtKB:Q7Z3B4] synonym: "54 kDa nucleoporin" EXACT [UniProtKB:Q7Z3B4] xref: EMBL:AAF67488.1 xref: EMBL:BAA91735.1 xref: EMBL:CAD97957.1 xref: UniProtKB:Q7Z3B4 xref: UniProtKB:Q96EA7 xref: UniProtKB:Q9NVL5 xref: UniProtKB:Q9P0I1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022465 ! NUP54_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0014994 ! nup54-nup62 physical interaction [Term] id: CCO:B0062781 name: CA190_HUMAN def: "Uncharacterized protein C1orf190" [UniProtKB:Q96LR2] xref: EMBL:AAH34422.1 xref: EMBL:BAB71608.1 xref: EMBL:CAH72471.1 xref: UniProtKB:Q96LR2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022082 ! C1orf190_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015002 ! loc541468-thap7 physical interaction relationship: participates_in CCO:I0015292 ! loc541468-loc55565 physical interaction relationship: participates_in CCO:I0015538 ! hgs-loc541468 physical interaction [Term] id: CCO:B0062782 name: CL031_HUMAN def: "UPF0446 protein C12orf31" [UniProtKB:Q9BRT6] xref: EMBL:AAH06002.1 xref: EMBL:AAH70232.1 xref: EMBL:AAI07781.1 xref: EMBL:BAC03699.1 xref: UniProtKB:Q3B766 xref: UniProtKB:Q9BRT6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022134 ! C12orf31_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015003 ! mgc14817-nfic physical interaction [Term] id: CCO:B0062783 name: CL011_HUMAN def: "Uncharacterized protein C12orf11" [UniProtKB:Q9NVM9] synonym: "Sarcoma antigen NY-SAR-95" EXACT [UniProtKB:Q9NVM9] xref: EMBL:AAH03081.1 xref: EMBL:AAH08368.1 xref: EMBL:AAO65180.1 xref: EMBL:BAA91721.1 xref: EMBL:BAA91725.1 xref: EMBL:CAB70726.1 xref: UniProtKB:Q86WE2 xref: UniProtKB:Q96HM2 xref: UniProtKB:Q9BTX2 xref: UniProtKB:Q9NTB6 xref: UniProtKB:Q9NVM5 xref: UniProtKB:Q9NVM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022132 ! C12orf11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015004 ! c12orf11-znf655 physical interaction relationship: transforms_into CCO:B0065877 ! CL011_HUMAN-Phosphoserine626 [Term] id: CCO:B0062784 name: HEBP2_HUMAN def: "Heme-binding protein 2" [UniProtKB:Q9Y5Z4] synonym: "Placental protein 23" EXACT [UniProtKB:Q9Y5Z4] synonym: "PP23" EXACT [UniProtKB:Q9Y5Z4] synonym: "Protein SOUL" EXACT [UniProtKB:Q9Y5Z4] xref: EMBL:AAD32099.1 xref: EMBL:AAH08205.1 xref: EMBL:AAH10290.1 xref: EMBL:AAH93037.1 xref: EMBL:AAL07394.1 xref: EMBL:AAR88624.1 xref: EMBL:CAI20539.1 xref: UniProtKB:Q96P57 xref: UniProtKB:Q9Y5Z4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022304 ! HEBP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015009 ! hebp2-pdcd6 physical interaction [Term] id: CCO:B0062785 name: CEP70_HUMAN def: "Centrosomal protein of 70 kDa" [UniProtKB:Q8NHQ1] synonym: "Cep70" EXACT [UniProtKB:Q8NHQ1] synonym: "p10-binding protein" EXACT [UniProtKB:Q8NHQ1] xref: EMBL:AAG35616.1 xref: EMBL:AAG35791.1 xref: EMBL:AAH16050.1 xref: EMBL:AAH30598.1 xref: EMBL:BAB14403.1 xref: UniProtKB:Q8NHQ1 xref: UniProtKB:Q96B31 xref: UniProtKB:Q9H2C3 xref: UniProtKB:Q9H2Z1 xref: UniProtKB:Q9H940 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022113 ! CEP70_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:I0015015 ! cep70-myst2 physical interaction relationship: participates_in CCO:I0015499 ! cep70-znf408 physical interaction relationship: participates_in CCO:I0015518 ! cep70-znf426 physical interaction relationship: participates_in CCO:I0015585 ! cep70-nrip1 physical interaction relationship: participates_in CCO:I0015732 ! cep70-tceb3b physical interaction [Term] id: CCO:B0062786 name: CR056_HUMAN def: "Putative uncharacterized protein C18orf56" [UniProtKB:Q8TAI1] xref: EMBL:AAH28301.1 xref: UniProtKB:Q8TAI1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022153 ! C18orf56_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015031 ! c18orf56-mdfi physical interaction [Term] id: CCO:B0062787 name: STX8_HUMAN def: "Syntaxin-8" [UniProtKB:Q9UNK0] xref: EMBL:AAC36466.1 xref: EMBL:AAC95285.1 xref: EMBL:AAD20831.1 xref: EMBL:AAH09713.1 xref: UniProtKB:O60712 xref: UniProtKB:Q9UNK0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022683 ! STX8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015032 ! creb3-stx8 physical interaction [Term] id: CCO:B0062788 name: ZN638_HUMAN def: "Zinc finger protein 638" [UniProtKB:Q14966] synonym: "CTCL tumor antigen se33-1" EXACT [UniProtKB:Q14966] synonym: "Cutaneous T-cell lymphoma-associated antigen se33-1" EXACT [UniProtKB:Q14966] synonym: "Nuclear protein 220" EXACT [UniProtKB:Q14966] synonym: "Zinc finger matrin-like protein" EXACT [UniProtKB:Q14966] xref: EMBL:AAF66079.1 xref: EMBL:AAG34909.1 xref: EMBL:AAH24000.1 xref: EMBL:AAH64530.1 xref: EMBL:AAH83513.1 xref: EMBL:AAM97681.1 xref: EMBL:AAY14979.1 xref: EMBL:BAA11748.1 xref: EMBL:CAD97667.1 xref: EMBL:CAH18177.1 xref: UniProtKB:Q14966 xref: UniProtKB:Q53R34 xref: UniProtKB:Q5XJ05 xref: UniProtKB:Q68DP3 xref: UniProtKB:Q6P2H2 xref: UniProtKB:Q7Z3T7 xref: UniProtKB:Q8NF92 xref: UniProtKB:Q8TCA1 xref: UniProtKB:Q9H2G1 xref: UniProtKB:Q9NP37 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022810 ! ZNF638_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015033 ! wwp1-znf638 physical interaction relationship: transforms_into CCO:B0072186 ! ZN638_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0072187 ! ZN638_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0072188 ! ZN638_HUMAN-Phosphoserine420 relationship: transforms_into CCO:B0072189 ! ZN638_HUMAN-Phosphoserine508 relationship: transforms_into CCO:B0072190 ! ZN638_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0072191 ! ZN638_HUMAN-Phosphoserine520 relationship: transforms_into CCO:B0072192 ! ZN638_HUMAN-Phosphoserine522 relationship: transforms_into CCO:B0072193 ! ZN638_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0072194 ! ZN638_HUMAN-Phosphoserine558 relationship: transforms_into CCO:B0072195 ! ZN638_HUMAN-Phosphoserine560 relationship: transforms_into CCO:B0072196 ! ZN638_HUMAN-Phosphoserine605 relationship: transforms_into CCO:B0072197 ! ZN638_HUMAN-Phosphoserine1100 relationship: transforms_into CCO:B0072198 ! ZN638_HUMAN-Phosphoserine1401 relationship: transforms_into CCO:B0072199 ! ZN638_HUMAN-Phosphoserine1825 relationship: transforms_into CCO:B0072200 ! ZN638_HUMAN-Phosphoserine1882 [Term] id: CCO:B0062789 name: MMTA2_HUMAN def: "Multiple myeloma tumor-associated protein 2" [UniProtKB:Q9BU76] synonym: "hMMTAG2" EXACT [UniProtKB:Q9BU76] xref: EMBL:AAH02843.1 xref: EMBL:AAH62585.1 xref: EMBL:AAN15215.1 xref: EMBL:BAC85598.1 xref: EMBL:BAC86431.1 xref: EMBL:CAI23119.1 xref: UniProtKB:Q6P5Y0 xref: UniProtKB:Q6ZTZ6 xref: UniProtKB:Q6ZWA6 xref: UniProtKB:Q8IZH3 xref: UniProtKB:Q9BU76 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022402 ! MMTAG2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015038 ! mmtag2-sdcbp2 physical interaction relationship: transforms_into CCO:B0068244 ! MMTA2_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0068245 ! MMTA2_HUMAN-Phosphoserine164 [Term] id: CCO:B0062790 name: PLOD3_HUMAN def: "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 precursor" [UniProtKB:O60568] synonym: "EC 1.14.11.4" EXACT [UniProtKB:O60568] synonym: "LH3" EXACT [UniProtKB:O60568] synonym: "Lysyl hydroxylase 3" EXACT [UniProtKB:O60568] xref: EMBL:AAC34808.1 xref: EMBL:AAC39753.1 xref: EMBL:AAD45831.1 xref: EMBL:AAF63701.1 xref: EMBL:AAH11674.1 xref: EMBL:AAO61775.1 xref: UniProtKB:O60568 xref: UniProtKB:Q540C3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022521 ! PLOD3_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001936 ! procollagen-lysine 5-dioxygenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001057 ! rough endoplasmic reticulum membrane relationship: participates_in CCO:I0015039 ! pepp2-plod3 physical interaction relationship: participates_in CCO:I0019412 ! plod3-pepp2 physical interaction [Term] id: CCO:B0062791 name: NECP2_HUMAN def: "Adaptin ear-binding coat-associated protein 2" [UniProtKB:Q9NVZ3] synonym: "NECAP endocytosis-associated protein 2" EXACT [UniProtKB:Q9NVZ3] synonym: "NECAP-2" EXACT [UniProtKB:Q9NVZ3] xref: EMBL:AAH17014.1 xref: EMBL:AAH18914.1 xref: EMBL:BAA91598.1 xref: EMBL:BAB14605.1 xref: EMBL:BAB15758.1 xref: EMBL:CAH71454.1 xref: EMBL:CAI22843.1 xref: UniProtKB:Q5VSU4 xref: UniProtKB:Q5VSU5 xref: UniProtKB:Q9H7L1 xref: UniProtKB:Q9H8L1 xref: UniProtKB:Q9NVZ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022443 ! NECAP2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000970 ! clathrin vesicle coat relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0015040 ! necap2-traf2 physical interaction relationship: participates_in CCO:I0015783 ! necap2-nmi physical interaction [Term] id: CCO:B0062792 name: TSNAX_HUMAN def: "Translin-associated protein X" [UniProtKB:Q99598] synonym: "Translin-associated factor X" EXACT [UniProtKB:Q99598] xref: EMBL:AAH10376.1 xref: EMBL:AAH11797.1 xref: EMBL:AAK58640.1 xref: EMBL:CAA64469.1 xref: UniProtKB:Q99598 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022744 ! TSNAX_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015043 ! gadd45g-tsnax physical interaction relationship: participates_in CCO:I0015407 ! pbxip1-tsnax physical interaction relationship: transforms_into CCO:B0071608 ! TSNAX_HUMAN-Phosphoserine33 relationship: transforms_into CCO:B0071609 ! TSNAX_HUMAN-Phosphotyrosine237 [Term] id: CCO:B0062793 name: BAHD1_HUMAN def: "Bromo adjacent homology domain-containing 1 protein" [UniProtKB:Q8TBE0] synonym: "BAH domain-containing protein 1" EXACT [UniProtKB:Q8TBE0] xref: EMBL:AAH22782.1 xref: EMBL:BAA76789.2 xref: EMBL:CAD38779.1 xref: UniProtKB:Q8NDF7 xref: UniProtKB:Q8TBE0 xref: UniProtKB:Q9Y2F4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022068 ! BAHD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015045 ! bahd1-mdfi physical interaction relationship: participates_in CCO:I0015065 ! bahd1-khdrbs3 physical interaction relationship: participates_in CCO:I0015486 ! bahd1-traf2 physical interaction relationship: participates_in CCO:I0015516 ! bahd1-dvl2 physical interaction relationship: transforms_into CCO:B0065792 ! BAHD1_HUMAN-Phosphoserine101 relationship: transforms_into CCO:B0065793 ! BAHD1_HUMAN-Phosphoserine121 [Term] id: CCO:B0062794 name: TRI32_HUMAN def: "Tripartite motif-containing protein 32" [UniProtKB:Q13049] synonym: "72 kDa Tat-interacting protein" EXACT [UniProtKB:Q13049] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q13049] synonym: "Zinc finger protein HT2A" EXACT [UniProtKB:Q13049] xref: EMBL:AAA86474.1 xref: EMBL:AAH03154.1 xref: EMBL:CAB92723.1 xref: UniProtKB:Q13049 xref: UniProtKB:Q9NQP8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022735 ! TRIM32_human relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015046 ! pde9a-trim32 physical interaction relationship: participates_in CCO:I0016174 ! atxn1-trim32 physical interaction relationship: participates_in CCO:I0017610 ! atxn1-trim32-1 physical interaction relationship: transforms_into CCO:B0071553 ! TRI32_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0071554 ! TRI32_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0071555 ! TRI32_HUMAN-Phosphoserine339 [Term] id: CCO:B0062795 name: CA165_HUMAN def: "Coiled-coil domain-containing protein C1orf165" [UniProtKB:Q7L4P6] xref: EMBL:AAH07932.2 xref: EMBL:AAH11804.1 xref: EMBL:BAB13864.1 xref: UniProtKB:Q7L4P6 xref: UniProtKB:Q96A62 xref: UniProtKB:Q9HAI3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022081 ! C1orf165_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015047 ! c1orf165-grap2 physical interaction relationship: participates_in CCO:I0015303 ! c1orf165-ctnnbip1 physical interaction relationship: participates_in CCO:I0020536 ! ddr1-c1orf165 physical interaction [Term] id: CCO:B0062796 name: ARMC7_HUMAN def: "Armadillo repeat-containing protein 7" [UniProtKB:Q9H6L4] xref: EMBL:AAH11728.1 xref: EMBL:BAB15242.1 xref: UniProtKB:Q9H6L4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022048 ! ARMC7_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015050 ! armc7-kctd13 physical interaction [Term] id: CCO:B0062797 name: AKIR2_HUMAN def: "Akirin-2" [UniProtKB:Q53H80] xref: EMBL:AAH00764.1 xref: EMBL:AAH03042.1 xref: EMBL:AAH05051.1 xref: EMBL:BAD96421.1 xref: EMBL:CAI21541.1 xref: UniProtKB:Q53H80 xref: UniProtKB:Q9BQB1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022031 ! Akirin2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015051 ! c6orf166-spg21 physical interaction relationship: transforms_into CCO:B0065556 ! AKIR2_HUMAN-Phosphoserine18 relationship: transforms_into CCO:B0065557 ! AKIR2_HUMAN-Phosphoserine21 [Term] id: CCO:B0062798 name: BAMBI_HUMAN def: "BMP and activin membrane-bound inhibitor homolog precursor" [UniProtKB:Q13145] synonym: "Non-metastatic gene A protein" EXACT [UniProtKB:Q13145] synonym: "Putative transmembrane protein NMA" EXACT [UniProtKB:Q13145] xref: EMBL:AAC50435.1 xref: EMBL:AAH19252.1 xref: EMBL:AAP35466.1 xref: EMBL:AAR02414.1 xref: EMBL:CAC16002.1 xref: UniProtKB:Q13145 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022069 ! BAMBI_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015053 ! bambi-sox30 physical interaction [Term] id: CCO:B0062799 name: Q9BRG3_HUMAN def: "C18orf45 protein (Chromosome 18 open reading frame 45) (cDNA, FLJ94820)" [UniProtKB:Q9BRG3] xref: EMBL:AAH06280.1 xref: EMBL:AAH54507.1 xref: EMBL:BAG36814.1 xref: EMBL:EAX01150.1 xref: UniProtKB:Q9BRG3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022857 ! C18orf45_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015058 ! c18orf45-mdfi physical interaction [Term] id: CCO:B0062800 name: ENOX1_HUMAN def: "Ecto-NOX disulfide-thiol exchanger 1" [UniProtKB:Q8TC92] synonym: "Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase" EXACT [UniProtKB:Q8TC92] synonym: "cCNOX" EXACT [UniProtKB:Q8TC92] synonym: "Cell proliferation-inducing gene 38 protein" EXACT [UniProtKB:Q8TC92] synonym: "cNOX" EXACT [UniProtKB:Q8TC92] synonym: "Constitutive Ecto-NOX" EXACT [UniProtKB:Q8TC92] xref: EMBL:AAH24178.1 xref: EMBL:AAT08035.1 xref: EMBL:ABO28524.1 xref: EMBL:BAA91442.1 xref: EMBL:CAH70584.2 xref: EMBL:CAH72199.2 xref: EMBL:CAI16283.2 xref: EMBL:EAX08693.1 xref: UniProtKB:A4GU15 xref: UniProtKB:A6NMH9 xref: UniProtKB:Q2TU81 xref: UniProtKB:Q5VT11 xref: UniProtKB:Q8TC92 xref: UniProtKB:Q9NWE0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022219 ! ENOX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015063 ! flj10094-nif3l1 physical interaction relationship: participates_in CCO:I0015799 ! cova1-flj10094 physical interaction relationship: participates_in CCO:I0019747 ! itgb3bp-flj10094 physical interaction relationship: transforms_into CCO:B0066008 ! ENOX1_HUMAN-Phosphoserine403 [Term] id: CCO:B0062801 name: Q8WWF6_HUMAN def: "DnaJ (Hsp40) homolog, subfamily B, member 3 (Putative uncharacterized protein tmp_locus_21) (HCG3 protein)" [UniProtKB:Q8WWF6] xref: EMBL:AAH17590.1 xref: EMBL:AAH24013.1 xref: EMBL:AAM08934.1 xref: EMBL:AAY24024.1 xref: UniProtKB:Q8WWF6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022848 ! DNAJB3_human relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015066 ! ewsr1-hcg3 physical interaction [Term] id: CCO:B0062802 name: FAS_HUMAN def: "Fatty acid synthase" [UniProtKB:P49327] synonym: "EC 2.3.1.85" EXACT [UniProtKB:P49327] xref: EMBL:AAA73576.1 xref: EMBL:AAB35516.1 xref: EMBL:AAC50259.1 xref: EMBL:AAH07267.1 xref: EMBL:AAH07909.1 xref: EMBL:AAH14634.2 xref: EMBL:AAH63242.1 xref: EMBL:AAS09886.1 xref: UniProtKB:P49327 xref: UniProtKB:Q13479 xref: UniProtKB:Q16702 xref: UniProtKB:Q6P4U5 xref: UniProtKB:Q6SS02 xref: UniProtKB:Q969R1 xref: UniProtKB:Q96C68 xref: UniProtKB:Q96IT0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022250 ! FASN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0015069 ! ewsr1-fasn physical interaction relationship: participates_in CCO:I0016621 ! map3k1-fasn physical interaction relationship: participates_in CCO:I0016714 ! map3k3-fasn physical interaction relationship: participates_in CCO:I0016805 ! nfkb2-fasn physical interaction relationship: transforms_into CCO:B0066134 ! FAS_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0066135 ! FAS_HUMAN-Phosphoserine207 relationship: transforms_into CCO:B0066136 ! FAS_HUMAN-Phosphoserine2198 relationship: transforms_into CCO:B0066137 ! FAS_HUMAN-Phosphothreonine2204 relationship: transforms_into CCO:B0066138 ! FAS_HUMAN-Phosphoserine2236 [Term] id: CCO:B0062803 name: APEX2_HUMAN def: "DNA-(apurinic or apyrimidinic site) lyase 2" [UniProtKB:Q9UBZ4] synonym: "AP endonuclease 2" EXACT [UniProtKB:Q9UBZ4] synonym: "AP endonuclease XTH2" EXACT [UniProtKB:Q9UBZ4] synonym: "APEX nuclease 2" EXACT [UniProtKB:Q9UBZ4] synonym: "APEX nuclease-like 2" EXACT [UniProtKB:Q9UBZ4] synonym: "Apurinic-apyrimidinic endonuclease 2" EXACT [UniProtKB:Q9UBZ4] synonym: "EC 4.2.99.18" EXACT [UniProtKB:Q9UBZ4] xref: EMBL:AAD43041.1 xref: EMBL:AAH02959.1 xref: EMBL:AAW56941.1 xref: EMBL:BAA78422.1 xref: EMBL:BAB13764.1 xref: EMBL:CAB45242.1 xref: EMBL:CAI43126.1 xref: UniProtKB:Q9UBZ4 xref: UniProtKB:Q9Y5X7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022043 ! APEX2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000411 ! DNA-(apurinic or apyrimidinic site) lyase activity relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0015070 ! apex2-traf2 physical interaction [Term] id: CCO:B0062804 name: S100P_HUMAN def: "Protein S100-P" [UniProtKB:P25815] synonym: "S100 calcium-binding protein P" EXACT [UniProtKB:P25815] xref: EMBL:AAH06819.1 xref: EMBL:AAO41114.1 xref: EMBL:AAP35953.1 xref: EMBL:CAA46566.1 xref: UniProtKB:P25815 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022623 ! S100P_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015074 ! s100a1-s100p physical interaction relationship: participates_in CCO:I0016005 ! s100a1-s100p-3 direct interaction relationship: participates_in CCO:I0016006 ! myh9-s100p direct interaction relationship: participates_in CCO:I0017960 ! s100a1-s100p-1 physical interaction relationship: participates_in CCO:I0019186 ! s100a1-s100p-2 physical interaction relationship: participates_in CCO:I0019187 ! s100a1-s100p-7 physical interaction relationship: participates_in CCO:I0019327 ! s100a1-s100p-4 colocalization [Term] id: CCO:B0062805 name: APBP2_HUMAN def: "Amyloid protein-binding protein 2" [UniProtKB:Q92624] synonym: "Amyloid beta precursor protein-binding protein 2" EXACT [UniProtKB:Q92624] synonym: "APP-BP2" EXACT [UniProtKB:Q92624] synonym: "Protein interacting with APP tail 1" EXACT [UniProtKB:Q92624] xref: EMBL:AAC83973.1 xref: EMBL:AAH18121.1 xref: EMBL:BAA13217.1 xref: UniProtKB:O95095 xref: UniProtKB:Q8WVC9 xref: UniProtKB:Q92624 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022042 ! APPBP2_human relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015075 ! appbp2-cntfr physical interaction relationship: participates_in CCO:I0015099 ! appbp2-c1orf166 physical interaction relationship: participates_in CCO:I0015124 ! appbp2-eid3 physical interaction relationship: participates_in CCO:I0015232 ! appbp2-creb3 physical interaction relationship: participates_in CCO:I0015432 ! appbp2-wnt5b physical interaction relationship: participates_in CCO:I0015702 ! appbp2-chmp5 physical interaction [Term] id: CCO:B0062806 name: Q96HZ8_HUMAN def: "Putative uncharacterized protein (ZCCHC14 protein)" [UniProtKB:Q96HZ8] xref: EMBL:AAH07926.1 xref: EMBL:AAH28304.1 xref: UniProtKB:Q96HZ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022854 ! ZCCHC14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015076 ! nfic-zcchc14 physical interaction [Term] id: CCO:B0062807 name: WWP2_HUMAN def: "NEDD4-like E3 ubiquitin-protein ligase WWP2" [UniProtKB:O00308] synonym: "AIP2" EXACT [UniProtKB:O00308] synonym: "Atrophin-1-interacting protein 2" EXACT [UniProtKB:O00308] synonym: "EC 6.3.2.-" EXACT [UniProtKB:O00308] synonym: "WW domain-containing protein 2" EXACT [UniProtKB:O00308] xref: EMBL:AAC51325.1 xref: EMBL:AAH00108.1 xref: EMBL:AAH13645.1 xref: EMBL:AAH64531.1 xref: EMBL:EAW83287.1 xref: UniProtKB:A6NEP1 xref: UniProtKB:O00308 xref: UniProtKB:Q96CZ2 xref: UniProtKB:Q9BWN6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022788 ! WWP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015084 ! ewsr1-wwp2 physical interaction relationship: participates_in CCO:I0015226 ! sf1-wwp2 physical interaction relationship: transforms_into CCO:B0071883 ! WWP2_HUMAN-Phosphoserine211 [Term] id: CCO:B0062808 name: SPAT2_HUMAN def: "Spermatogenesis-associated protein 2" [UniProtKB:Q9UM82] synonym: "Spermatogenesis-associated protein PD1" EXACT [UniProtKB:Q9UM82] xref: EMBL:AAD28324.1 xref: EMBL:AAH09481.1 xref: EMBL:BAA34477.2 xref: EMBL:CAB46029.1 xref: UniProtKB:O94857 xref: UniProtKB:Q9UM82 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022669 ! SPATA2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015092 ! spata2-traf2 physical interaction relationship: participates_in CCO:I0015127 ! dut-spata2 physical interaction relationship: transforms_into CCO:B0070789 ! SPAT2_HUMAN-Phosphoserine253 [Term] id: CCO:B0062809 name: HOOK2_HUMAN def: "Protein Hook homolog 2" [UniProtKB:Q96ED9] synonym: "h-hook2" EXACT [UniProtKB:Q96ED9] synonym: "hHK2" EXACT [UniProtKB:Q96ED9] xref: EMBL:AAC09299.1 xref: EMBL:AAH12443.1 xref: UniProtKB:O60562 xref: UniProtKB:Q96ED9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022313 ! HOOK2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0015093 ! hook2-myst2 physical interaction relationship: participates_in CCO:I0015370 ! hook2-znf250 physical interaction relationship: participates_in CCO:I0015479 ! hook2-ralbp1 physical interaction relationship: participates_in CCO:I0015573 ! drr1-hook2 physical interaction relationship: participates_in CCO:I0015709 ! eps8-hook2 physical interaction relationship: transforms_into CCO:B0066891 ! HOOK2_HUMAN-Phosphoserine163 [Term] id: CCO:B0062810 name: CP048_HUMAN def: "Uncharacterized protein C16orf48" [UniProtKB:Q9H0I2] xref: EMBL:AAH08284.1 xref: EMBL:AAQ89193.1 xref: EMBL:CAB66720.1 xref: UniProtKB:Q6UWD7 xref: UniProtKB:Q9H0I2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022148 ! C16orf48_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: participates_in CCO:I0015096 ! c16orf48-tsc22d4 physical interaction relationship: participates_in CCO:I0015128 ! c16orf48-traf2 physical interaction relationship: participates_in CCO:I0015222 ! c16orf48-mdfi physical interaction relationship: participates_in CCO:I0015607 ! c16orf48-dvl2 physical interaction [Term] id: CCO:B0062811 name: NDUB1_HUMAN def: "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1" [UniProtKB:O75438] synonym: "CI-MNLL" EXACT [UniProtKB:O75438] synonym: "Complex I-MNLL" EXACT [UniProtKB:O75438] synonym: "NADH-ubiquinone oxidoreductase MNLL subunit" EXACT [UniProtKB:O75438] xref: EMBL:AAC39914.1 xref: EMBL:AAD42054.1 xref: EMBL:AAH09691.2 xref: UniProtKB:O75438 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022437 ! NDUFB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015107 ! ewsr1-ndufb1 physical interaction [Term] id: CCO:B0062812 name: DYL2_HUMAN def: "Dynein light chain 2, cytoplasmic" [UniProtKB:Q96FJ2] synonym: "Dynein light chain LC8-type 2" EXACT [UniProtKB:Q96FJ2] xref: EMBL:AAH10744.1 xref: EMBL:AAP97230.1 xref: UniProtKB:Q96FJ2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022201 ! DYNLL2_human relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0000995 ! dynein complex relationship: participates_in CCO:I0015110 ! birc4-dlc2 physical interaction relationship: participates_in CCO:I0015427 ! dlc2-homer3 physical interaction relationship: participates_in CCO:I0015438 ! dlc2-ewsr1 physical interaction [Term] id: CCO:B0062813 name: YB056_HUMAN def: "Uncharacterized protein MGC13057" [UniProtKB:Q9BSF0] xref: EMBL:AAH05083.1 xref: EMBL:AAX93233.1 xref: EMBL:BAG36193.1 xref: EMBL:EAX10878.1 xref: UniProtKB:Q53TC7 xref: UniProtKB:Q9BSF0 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015112 ! mgc13057-prkar1a physical interaction relationship: transforms_into CCO:B0071918 ! YB056_HUMAN-Phosphoserine40 [Term] id: CCO:B0062814 name: GFAP_HUMAN def: "Glial fibrillary acidic protein" [UniProtKB:P14136] synonym: "GFAP" EXACT [UniProtKB:P14136] xref: EMBL:AAA52528.1 xref: EMBL:AAA52529.1 xref: EMBL:AAB22581.1 xref: EMBL:AAH13596.1 xref: EMBL:AAH41765.1 xref: EMBL:AAH62609.1 xref: EMBL:AAL16662.1 xref: EMBL:AAN87903.1 xref: EMBL:AAN87904.1 xref: EMBL:AAN87907.1 xref: EMBL:BAC87610.1 xref: EMBL:BAD96403.1 xref: EMBL:CAB61354.2 xref: EMBL:CAC69881.1 xref: UniProtKB:P14136 xref: UniProtKB:Q53H98 xref: UniProtKB:Q5D055 xref: UniProtKB:Q6ZQS3 xref: UniProtKB:Q7Z5J6 xref: UniProtKB:Q7Z5J7 xref: UniProtKB:Q96KS4 xref: UniProtKB:Q96P18 xref: UniProtKB:Q9UFD0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022275 ! GFAP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015113 ! gfap-pdlim1 physical interaction relationship: participates_in CCO:I0015569 ! gfap-grap2 physical interaction relationship: participates_in CCO:I0015616 ! gfap-pdzk1 physical interaction relationship: participates_in CCO:I0018874 ! app-nsf-2 physical interaction relationship: transforms_into CCO:B0066445 ! GFAP_HUMAN-Phosphothreonine110 relationship: transforms_into CCO:B0066446 ! GFAP_HUMAN-Phosphothreonine383 [Term] id: CCO:B0062815 name: CC116_HUMAN def: "Coiled-coil domain-containing protein 116" [UniProtKB:Q8IYX3] xref: EMBL:AAH33499.1 xref: EMBL:BAC04145.1 xref: UniProtKB:Q8IYX3 xref: UniProtKB:Q8N9Y9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022096 ! CCDC116_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015114 ! flj36046-mdfi physical interaction [Term] id: CCO:B0062816 name: NSUN4_HUMAN def: "Putative methyltransferase NSUN4" [UniProtKB:Q96CB9] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q96CB9] synonym: "NOL1/NOP2/Sun domain family member 4" EXACT [UniProtKB:Q96CB9] xref: EMBL:AAH14441.1 xref: EMBL:AAH16907.1 xref: EMBL:BAB13847.1 xref: EMBL:CAI21962.1 xref: UniProtKB:Q5TDF7 xref: UniProtKB:Q96AN8 xref: UniProtKB:Q96CB9 xref: UniProtKB:Q9HAJ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022459 ! NSUN4_human relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015120 ! ewsr1-nsun4 physical interaction [Term] id: CCO:B0062817 name: KRR1_HUMAN def: "KRR1 small subunit processome component homolog" [UniProtKB:Q13601] synonym: "HIV-1 Rev-binding protein 2" EXACT [UniProtKB:Q13601] synonym: "Rev-interacting protein 1" EXACT [UniProtKB:Q13601] synonym: "Rip-1" EXACT [UniProtKB:Q13601] xref: EMBL:AAB00557.1 xref: EMBL:AAH16778.1 xref: EMBL:AAH26107.1 xref: EMBL:AAH33887.1 xref: UniProtKB:Q13601 xref: UniProtKB:Q8NEA8 xref: UniProtKB:Q8TC37 xref: UniProtKB:Q96AT5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022357 ! KRR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015129 ! ewsr1-hrb2 physical interaction relationship: transforms_into CCO:B0067444 ! KRR1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0067445 ! KRR1_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0067446 ! KRR1_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0067447 ! KRR1_HUMAN-Phosphothreonine337 relationship: transforms_into CCO:B0067448 ! KRR1_HUMAN-Phosphothreonine339 [Term] id: CCO:B0062818 name: Q6PKC6_HUMAN def: "WDR6 protein" [UniProtKB:Q6PKC6] xref: EMBL:AAH02826.1 xref: UniProtKB:Q6PKC6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022840 ! WDR6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015135 ! cdc42ep4-wdr6 physical interaction [Term] id: CCO:B0062819 name: PRAF1_HUMAN def: "Prenylated Rab acceptor protein 1" [UniProtKB:Q9UI14] synonym: "PRA1 family protein 1" EXACT [UniProtKB:Q9UI14] xref: EMBL:AAF17190.1 xref: EMBL:AAH08950.1 xref: EMBL:AAP97229.1 xref: EMBL:AAV38767.1 xref: EMBL:CAB43107.1 xref: EMBL:CAG33495.1 xref: EMBL:CAG46913.1 xref: UniProtKB:Q7Z4Y2 xref: UniProtKB:Q9UI14 xref: UniProtKB:Q9Y3R1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022528 ! RABAC1_human relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0015136 ! rab33a-rabac1 physical interaction relationship: participates_in CCO:I0015212 ! rabac1-spg21 physical interaction relationship: participates_in CCO:I0015623 ! nif3l1-rabac1 physical interaction relationship: participates_in CCO:I0015825 ! rab1a-rabac1 physical interaction [Term] id: CCO:B0062820 name: Q96BR9_HUMAN def: "Zinc finger and BTB domain containing 8" [UniProtKB:Q96BR9] synonym: "cDNA FLJ90065 fis, clone HEMBA1003497, weakly similar to ZINC FINGER PROTEIN 151" EXACT [UniProtKB:Q96BR9] synonym: "HCG39683, isoform CRA_b" EXACT [UniProtKB:Q96BR9] xref: EMBL:AAH15239.1 xref: EMBL:BAC11050.1 xref: EMBL:EAX07522.1 xref: UniProtKB:Q96BR9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0020571 ! ZBTB8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015137 ! myst2-q96br9 physical interaction relationship: participates_in CCO:I0015145 ! hkr3-q96br9 physical interaction relationship: participates_in CCO:I0015239 ! lmo3-q96br9 physical interaction relationship: participates_in CCO:I0015487 ! dvl2-q96br9 physical interaction relationship: participates_in CCO:I0015646 ! q96br9-zfp276 physical interaction relationship: participates_in CCO:I0015764 ! q96br9-znf408 physical interaction relationship: participates_in CCO:I0015769 ! q96br9-znf250 physical interaction [Term] id: CCO:B0062821 name: SSBP4_HUMAN def: "Single-stranded DNA-binding protein 4" [UniProtKB:Q9BWG4] xref: EMBL:AAH00274.1 xref: UniProtKB:Q9BWG4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022678 ! SSBP4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015138 ! ldb1-ssbp4 physical interaction relationship: transforms_into CCO:B0070935 ! SSBP4_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0070936 ! SSBP4_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0070937 ! SSBP4_HUMAN-Phosphothreonine355 [Term] id: CCO:B0062822 name: CK065_HUMAN def: "Uncharacterized protein C11orf65" [UniProtKB:Q8NCR3] xref: EMBL:AAH29536.1 xref: EMBL:AAH59411.1 xref: UniProtKB:Q6PCA8 xref: UniProtKB:Q8NCR3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022130 ! C11orf65_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015140 ! mgc33948-sumo1 physical interaction [Term] id: CCO:B0062823 name: HPCL4_HUMAN def: "Hippocalcin-like protein 4" [UniProtKB:Q9UM19] synonym: "HLP4" EXACT [UniProtKB:Q9UM19] xref: EMBL:AAH30827.1 xref: EMBL:BAA86892.1 xref: EMBL:CAB66526.1 xref: EMBL:CAI19574.1 xref: UniProtKB:Q5TG97 xref: UniProtKB:Q8N611 xref: UniProtKB:Q9UM19 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022315 ! HPCAL4_human relationship: has_function CCO:F0001514 ! calcium channel regulator activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015142 ! dtx2-hpcal4 physical interaction relationship: participates_in CCO:I0015736 ! hpcal4-tsc22d3 physical interaction [Term] id: CCO:B0062824 name: AP2M1_HUMAN def: "AP-2 complex subunit mu-1" [UniProtKB:Q96CW1] synonym: "Adaptin-mu2" EXACT [UniProtKB:Q96CW1] synonym: "AP-2 mu-2 chain" EXACT [UniProtKB:Q96CW1] synonym: "Clathrin assembly protein complex 2 medium chain" EXACT [UniProtKB:Q96CW1] synonym: "Clathrin coat assembly protein AP50" EXACT [UniProtKB:Q96CW1] synonym: "Clathrin coat-associated protein AP50" EXACT [UniProtKB:Q96CW1] synonym: "HA2 50 kDa subunit" EXACT [UniProtKB:Q96CW1] synonym: "Plasma membrane adaptor AP-2 50 kDa protein" EXACT [UniProtKB:Q96CW1] xref: EMBL:AAA93254.1 xref: EMBL:AAH04996.1 xref: EMBL:AAH13796.1 xref: EMBL:AAH14030.1 xref: EMBL:AAP35972.1 xref: EMBL:BAA09762.2 xref: EMBL:EAW78290.1 xref: UniProtKB:A6NE12 xref: UniProtKB:P20172 xref: UniProtKB:P53679 xref: UniProtKB:Q96CW1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022039 ! AP2M1_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: located_in CCO:C0000977 ! clathrin coat of coated pit relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0015143 ! ap2m1-dvl2 physical interaction relationship: participates_in CCO:I0015233 ! ap2m1-med4 physical interaction relationship: participates_in CCO:I0015244 ! ap2m1-znfn1a1 physical interaction relationship: participates_in CCO:I0015542 ! ap2m1-tbc1d5 physical interaction relationship: transforms_into CCO:B0065665 ! AP2M1_HUMAN-Phosphothreonine156 [Term] id: CCO:B0062825 name: TIFA_HUMAN def: "TRAF-interacting protein with FHA domain-containing protein A" [UniProtKB:Q96CG3] synonym: "Putative MAPK-activating protein PM14" EXACT [UniProtKB:Q96CG3] synonym: "Putative NF-kappa-B-activating protein 20" EXACT [UniProtKB:Q96CG3] synonym: "TRAF2-binding protein" EXACT [UniProtKB:Q96CG3] xref: EMBL:AAH14259.1 xref: EMBL:AAY40963.1 xref: EMBL:BAB86902.1 xref: EMBL:BAC77364.1 xref: EMBL:BAC77391.1 xref: EMBL:BAF85589.1 xref: EMBL:EAX06273.1 xref: UniProtKB:Q96CG3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022714 ! TIFA_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015152 ! sdcbp2-tifa physical interaction relationship: participates_in CCO:I0015274 ! dvl2-tifa physical interaction relationship: participates_in CCO:I0015296 ! nif3l1-tifa physical interaction relationship: participates_in CCO:I0015820 ! tifa-traf2 physical interaction [Term] id: CCO:B0062826 name: DPY30_HUMAN def: "Protein dpy-30 homolog" [UniProtKB:Q9C005] synonym: "Dpy-30-like protein" EXACT [UniProtKB:Q9C005] xref: EMBL:AAH15970.1 xref: EMBL:AAK00640.1 xref: UniProtKB:Q9C005 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022196 ! DPY30_human relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015154 ! ash2l-loc84661 physical interaction [Term] id: CCO:B0062827 name: LRRN4_HUMAN def: "Leucine-rich repeat neuronal protein 4 precursor" [UniProtKB:Q8WUT4] synonym: "Neuronal leucine-rich repeat protein 4" EXACT [UniProtKB:Q8WUT4] synonym: "NLRR-4" EXACT [UniProtKB:Q8WUT4] xref: EMBL:AAH27720.1 xref: EMBL:CAI23479.1 xref: EMBL:CAI42165.1 xref: UniProtKB:Q5JWV6 xref: UniProtKB:Q8WUT4 xref: UniProtKB:Q9H419 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022377 ! LRRN4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015158 ! c20orf75-mdfi physical interaction [Term] id: CCO:B0062828 name: CC120_HUMAN def: "Coiled-coil domain-containing protein 120" [UniProtKB:Q96HB5] xref: EMBL:AAH08769.1 xref: UniProtKB:Q96HB5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022097 ! CCDC120_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015160 ! jm11-pscd2 physical interaction relationship: participates_in CCO:I0015421 ! jm11-mdfi physical interaction relationship: transforms_into CCO:B0065834 ! CC120_HUMAN-Phosphoserine331 relationship: transforms_into CCO:B0065835 ! CC120_HUMAN-Phosphoserine358 [Term] id: CCO:B0062829 name: Q6GU34_HUMAN def: "NCK interacting protein with SH3 domain" [UniProtKB:Q6GU34] xref: EMBL:AAH16052.1 xref: UniProtKB:Q6GU34 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0020017 ! NCKIPSD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015162 ! baiap2-nckipsd physical interaction relationship: participates_in CCO:I0015504 ! nck2-nckipsd physical interaction [Term] id: CCO:B0062830 name: R3GEF_HUMAN def: "Guanine nucleotide exchange factor for Rab3A" [UniProtKB:Q8TBN0] synonym: "Rab3A-interacting-like protein 1" EXACT [UniProtKB:Q8TBN0] synonym: "Rabin3-like 1" EXACT [UniProtKB:Q8TBN0] xref: EMBL:AAF28399.1 xref: EMBL:AAH22239.1 xref: EMBL:AAH51820.1 xref: UniProtKB:Q86V32 xref: UniProtKB:Q8TBN0 xref: UniProtKB:Q9P1Q8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022551 ! RAB3IL1_human relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015164 ! rab11a-rab3il1 physical interaction [Term] id: CCO:B0062831 name: SHPS1_HUMAN def: "Tyrosine-protein phosphatase non-receptor type substrate 1 precursor" [UniProtKB:P78324] synonym: "Bit" EXACT [UniProtKB:P78324] synonym: "Brain Ig-like molecule with tyrosine-based activation motifs" EXACT [UniProtKB:P78324] synonym: "CD172 antigen-like family member A" EXACT [UniProtKB:P78324] synonym: "CD172a antigen" EXACT [UniProtKB:P78324] synonym: "Inhibitory receptor SHPS-1" EXACT [UniProtKB:P78324] synonym: "Macrophage fusion receptor" EXACT [UniProtKB:P78324] synonym: "MyD-1 antigen" EXACT [UniProtKB:P78324] synonym: "p84" EXACT [UniProtKB:P78324] synonym: "SHP substrate 1" EXACT [UniProtKB:P78324] synonym: "SHPS-1" EXACT [UniProtKB:P78324] synonym: "Signal-regulatory protein alpha-1" EXACT [UniProtKB:P78324] synonym: "Sirp-alpha-1" EXACT [UniProtKB:P78324] synonym: "Sirp-alpha-2" EXACT [UniProtKB:P78324] synonym: "Sirp-alpha-3" EXACT [UniProtKB:P78324] xref: EMBL:AAF19260.1 xref: EMBL:AAH26692.1 xref: EMBL:AAH33092.1 xref: EMBL:AAH38510.1 xref: EMBL:AAH75849.1 xref: EMBL:BAA12974.1 xref: EMBL:BAA87929.1 xref: EMBL:CAA71403.1 xref: EMBL:CAA71944.1 xref: EMBL:CAB38874.2 xref: EMBL:CAC12723.2 xref: UniProtKB:O00683 xref: UniProtKB:O43799 xref: UniProtKB:P78324 xref: UniProtKB:Q8N517 xref: UniProtKB:Q8TAL8 xref: UniProtKB:Q9H0Z2 xref: UniProtKB:Q9UDX2 xref: UniProtKB:Q9UIJ6 xref: UniProtKB:Q9Y4U9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022652 ! SIRPA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015166 ! nol3-ptpns1 physical interaction relationship: participates_in CCO:I0015981 ! ptpn6-sirpa-1 physical interaction relationship: transforms_into CCO:B0070507 ! SHPS1_HUMAN-Phosphotyrosine428 relationship: transforms_into CCO:B0070508 ! SHPS1_HUMAN-Phosphotyrosine452 relationship: transforms_into CCO:B0070509 ! SHPS1_HUMAN-Phosphotyrosine469 relationship: transforms_into CCO:B0070510 ! SHPS1_HUMAN-Phosphotyrosine495 [Term] id: CCO:B0062832 name: EAA3_HUMAN def: "Excitatory amino acid transporter 3" [UniProtKB:P43005] synonym: "Excitatory amino-acid carrier 1" EXACT [UniProtKB:P43005] synonym: "Neuronal and epithelial glutamate transporter" EXACT [UniProtKB:P43005] synonym: "Sodium-dependent glutamate/aspartate transporter 3" EXACT [UniProtKB:P43005] synonym: "Solute carrier family 1 member 1" EXACT [UniProtKB:P43005] xref: EMBL:AAA50430.1 xref: EMBL:AAA53215.1 xref: EMBL:AAA68628.1 xref: EMBL:AAC25029.1 xref: EMBL:AAC27511.3 xref: EMBL:AAH33040.1 xref: EMBL:BAB83767.1 xref: EMBL:CAH71965.1 xref: EMBL:CAI41264.1 xref: UniProtKB:O75587 xref: UniProtKB:P43005 xref: UniProtKB:Q5VZ24 xref: UniProtKB:Q8N199 xref: UniProtKB:Q9UEW2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022207 ! SLC1A1_human relationship: has_function CCO:F0001552 ! L-glutamate transmembrane transporter activity relationship: has_function CCO:F0002742 ! symporter activity relationship: has_function CCO:F0003597 ! sodium:dicarboxylate symporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015176 ! ewsr1-slc1a1 physical interaction [Term] id: CCO:B0062833 name: Q9NXX0_HUMAN def: "CDNA FLJ20011 fis, clone ADKA03432 (ILF3 protein) (CDNA: FLJ22168 fis, clone HRC00618)" [UniProtKB:Q9NXX0] xref: EMBL:AAH03086.1 xref: EMBL:BAA90887.1 xref: EMBL:BAB15245.1 xref: EMBL:CAG33504.1 xref: UniProtKB:Q9NXX0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004884 ! ILF3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015180 ! ilf3-trip6 physical interaction relationship: participates_in CCO:I0015340 ! ilf3-mdfi physical interaction [Term] id: CCO:B0062834 name: DPPA4_HUMAN def: "Developmental pluripotency-associated protein 4" [UniProtKB:Q7L190] xref: EMBL:AAH32846.2 xref: EMBL:BAA91765.1 xref: EMBL:BAB14188.1 xref: UniProtKB:Q7L190 xref: UniProtKB:Q9H9N5 xref: UniProtKB:Q9NVI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022195 ! DPPA4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015184 ! dppa4-ldoc1 physical interaction relationship: participates_in CCO:I0019407 ! sh3gl1-dppa4-1 physical interaction relationship: participates_in CCO:I0019979 ! dppa4-sh3gl1 physical interaction relationship: participates_in CCO:I0019980 ! sh3gl1-dppa4 physical interaction relationship: participates_in CCO:I0019981 ! dppa4-sh3gl3 physical interaction [Term] id: CCO:B0062835 name: Q8IV21_HUMAN def: "Solute carrier family 35 (UDP-galactose transporter), member A2" [UniProtKB:Q8IV21] synonym: "Solute carrier family 35 (UDP-galactose transporter), member A2, isoform CRA_c" EXACT [UniProtKB:Q8IV21] xref: EMBL:AAH35747.1 xref: EMBL:EAW50733.1 xref: UniProtKB:Q8IV21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022843 ! SLC35A2_human relationship: has_function CCO:F0001577 ! sugar:hydrogen symporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015195 ! mdfi-slc35a2 physical interaction [Term] id: CCO:B0062836 name: Q8WVG2_HUMAN def: "WDR37 protein" [UniProtKB:Q8WVG2] xref: EMBL:AAH18044.1 xref: UniProtKB:Q8WVG2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022782 ! WDR37_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015199 ! ewsr1-wdr37 physical interaction [Term] id: CCO:B0062837 name: CPSF5_HUMAN def: "Cleavage and polyadenylation specificity factor subunit 5" [UniProtKB:O43809] synonym: "Cleavage and polyadenylation specificity factor 25 kDa subunit" EXACT [UniProtKB:O43809] synonym: "CPSF 25 kDa subunit" EXACT [UniProtKB:O43809] synonym: "Nucleoside diphosphate-linked moiety X motif 21" EXACT [UniProtKB:O43809] synonym: "Nudix motif 21" EXACT [UniProtKB:O43809] synonym: "Pre-mRNA cleavage factor Im 25 kDa subunit" EXACT [UniProtKB:O43809] xref: EMBL:AAH01403.1 xref: EMBL:CAA05026.1 xref: EMBL:CAD97606.1 xref: EMBL:CAG33200.1 xref: UniProtKB:O43809 xref: UniProtKB:Q6IB85 xref: UniProtKB:Q6NE84 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022149 ! NUDT21_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015202 ! cpsf5-nif3l1 physical interaction relationship: participates_in CCO:I0016162 ! atxn1-cpsf5 physical interaction relationship: participates_in CCO:I0016469 ! ikbke-o43809 physical interaction relationship: participates_in CCO:I0016864 ! relb-o43809 physical interaction relationship: participates_in CCO:I0017554 ! cpsf5-atxn1 physical interaction relationship: transforms_into CCO:B0065891 ! CPSF5_HUMAN-Phosphotyrosine40 [Term] id: CCO:B0062838 name: CS060_HUMAN def: "Uncharacterized protein C19orf60" [UniProtKB:Q96EN9] xref: EMBL:AAH12078.1 xref: EMBL:BAA91400.1 xref: EMBL:BAC03773.1 xref: EMBL:EAW84723.1 xref: UniProtKB:Q8NAX4 xref: UniProtKB:Q96EN9 xref: UniProtKB:Q9NWI0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022155 ! C19orf60_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015206 ! flj20850-mdfi physical interaction [Term] id: CCO:B0062839 name: TM147_HUMAN def: "Transmembrane protein 147" [UniProtKB:Q9BVK8] synonym: "Protein NIFIE 14" EXACT [UniProtKB:Q9BVK8] xref: EMBL:AAH01118.1 xref: EMBL:CAA77013.1 xref: UniProtKB:O75790 xref: UniProtKB:Q9BVK8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022717 ! TMEM147_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015211 ! abi3-nifie14 physical interaction [Term] id: CCO:B0062840 name: CG034_HUMAN def: "Uncharacterized protein C7orf34 precursor" [UniProtKB:Q96L11] synonym: "MSSP-binding protein CTM-1" EXACT [UniProtKB:Q96L11] xref: EMBL:AAH14596.1 xref: EMBL:BAB88941.1 xref: EMBL:BAB88942.1 xref: EMBL:EAL23778.1 xref: UniProtKB:A4D2H8 xref: UniProtKB:Q8TDV6 xref: UniProtKB:Q96L11 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022117 ! C7orf34_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015217 ! c7orf34-hkr3 physical interaction [Term] id: CCO:B0062841 name: DDX17_HUMAN def: "Probable ATP-dependent RNA helicase DDX17" [UniProtKB:Q92841] synonym: "DEAD box protein 17" EXACT [UniProtKB:Q92841] synonym: "DEAD box protein p72" EXACT [UniProtKB:Q92841] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q92841] synonym: "RNA-dependent helicase p72" EXACT [UniProtKB:Q92841] xref: EMBL:AAC50787.1 xref: EMBL:AAH00595.2 xref: EMBL:CAB09792.1 xref: EMBL:CAG30318.1 xref: EMBL:CAH10627.2 xref: UniProtKB:Q69YT1 xref: UniProtKB:Q6ICD6 xref: UniProtKB:Q92841 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022174 ! DDX17_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001767 ! RNA-dependent ATPase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0015218 ! ddx17-sf1 physical interaction relationship: transforms_into CCO:B0065926 ! DDX17_HUMAN-Phosphotyrosine200 relationship: transforms_into CCO:B0065927 ! DDX17_HUMAN-Phosphothreonine444 relationship: transforms_into CCO:B0065928 ! DDX17_HUMAN-Phosphoserine593 relationship: transforms_into CCO:B0065929 ! DDX17_HUMAN-Phosphoserine597 [Term] id: CCO:B0062842 name: CL012_HUMAN def: "Uncharacterized protein C12orf12" [UniProtKB:Q8TC90] xref: EMBL:AAH24183.1 xref: EMBL:AAH26075.1 xref: EMBL:AAH27600.1 xref: EMBL:AAH34491.1 xref: UniProtKB:Q8TC47 xref: UniProtKB:Q8TC90 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022133 ! C12orf12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015220 ! c12orf12-mdfi physical interaction [Term] id: CCO:B0062843 name: GNMT_HUMAN def: "Glycine N-methyltransferase" [UniProtKB:Q14749] synonym: "EC 2.1.1.20" EXACT [UniProtKB:Q14749] xref: EMBL:AAF78289.1 xref: EMBL:AAF78290.1 xref: EMBL:AAH32627.1 xref: EMBL:CAA44164.1 xref: UniProtKB:Q14749 xref: UniProtKB:Q9NNZ1 xref: UniProtKB:Q9NS24 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022282 ! GNMT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015228 ! gnmt-nif3l1 physical interaction relationship: participates_in CCO:I0015298 ! arrb1-gnmt physical interaction relationship: transforms_into CCO:B0066503 ! GNMT_HUMAN-N-acetylvaline2 relationship: transforms_into CCO:B0066504 ! GNMT_HUMAN-Phosphoserine235 [Term] id: CCO:B0062844 name: AQP5_HUMAN def: "Aquaporin-5" [UniProtKB:P55064] synonym: "AQP-5" EXACT [UniProtKB:P55064] xref: EMBL:AAC50474.1 xref: EMBL:AAH32946.1 xref: UniProtKB:P55064 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022046 ! AQP5_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0002717 ! water channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: participates_in CCO:I0015229 ! aqp5-mdfi physical interaction [Term] id: CCO:B0062845 name: RAI2_HUMAN def: "Retinoic acid-induced protein 2" [UniProtKB:Q9Y5P3] xref: EMBL:AAD33688.1 xref: EMBL:AAH27937.1 xref: EMBL:CAI42725.1 xref: UniProtKB:B1B1K2 xref: UniProtKB:Q8N6X7 xref: UniProtKB:Q9Y5P3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022556 ! RAI2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0015235 ! ctbp2-rai2 physical interaction [Term] id: CCO:B0062846 name: RN183_HUMAN def: "RING finger protein 183" [UniProtKB:Q96D59] xref: EMBL:AAH13036.1 xref: UniProtKB:Q96D59 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022591 ! RNF183_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015240 ! ewsr1-rnf183 physical interaction [Term] id: CCO:B0062847 name: DHRS1_HUMAN def: "Dehydrogenase/reductase SDR family member 1" [UniProtKB:Q96LJ7] synonym: "EC 1.1.-.-" EXACT [UniProtKB:Q96LJ7] xref: EMBL:AAH14057.1 xref: EMBL:AAH15943.1 xref: EMBL:AAN32660.1 xref: EMBL:BAB71694.1 xref: EMBL:CAD38773.1 xref: EMBL:CAD62314.1 xref: UniProtKB:Q8NDG3 xref: UniProtKB:Q96B59 xref: UniProtKB:Q96CQ5 xref: UniProtKB:Q96LJ7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022185 ! DHRS1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:I0015242 ! dhrs1-mdfi physical interaction [Term] id: CCO:B0062848 name: NO40_HUMAN def: "Nucleolar protein of 40 kDa" [UniProtKB:Q9NP64] synonym: "Pnn-interacting nucleolar protein" EXACT [UniProtKB:Q9NP64] synonym: "pNO40" EXACT [UniProtKB:Q9NP64] synonym: "PS1D protein" EXACT [UniProtKB:Q9NP64] synonym: "Putative S1 RNA-binding domain protein" EXACT [UniProtKB:Q9NP64] synonym: "Zinc finger CCHC domain-containing protein 17" EXACT [UniProtKB:Q9NP64] xref: EMBL:AAF36163.1 xref: EMBL:AAF36171.1 xref: EMBL:AAF72518.3 xref: EMBL:AAH00685.1 xref: EMBL:AAH07446.1 xref: EMBL:AAH50609.1 xref: EMBL:BAA91984.1 xref: EMBL:BAB14066.1 xref: EMBL:BAB14799.1 xref: EMBL:CAH71849.1 xref: UniProtKB:Q6PKH4 xref: UniProtKB:Q9NP64 xref: UniProtKB:Q9NYG4 xref: UniProtKB:Q9P0M8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022448 ! ZCCHC17_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0015247 ! ps1d-sdcbp2 physical interaction relationship: transforms_into CCO:B0068756 ! NO40_HUMAN-Phosphoserine114 [Term] id: CCO:B0062849 name: RD23A_HUMAN def: "UV excision repair protein RAD23 homolog A" [UniProtKB:P54725] synonym: "hHR23A" EXACT [UniProtKB:P54725] xref: EMBL:AAB51177.1 xref: EMBL:AAH14026.1 xref: EMBL:AAN39383.1 xref: EMBL:BAA04767.1 xref: UniProtKB:P54725 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022563 ! RAD23A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015251 ! rad23a-sqstm1 physical interaction relationship: participates_in CCO:I0015344 ! ewsr1-rad23a physical interaction relationship: participates_in CCO:I0015786 ! rad23a-traf2 physical interaction relationship: participates_in CCO:I0017614 ! atxn3-rad23a physical interaction relationship: participates_in CCO:I0019125 ! atxn7-rad23a physical interaction relationship: participates_in CCO:I0019428 ! rad23a-sqstm1-1 physical interaction relationship: transforms_into CCO:B0069847 ! RD23A_HUMAN-Phosphoserine123 relationship: transforms_into CCO:B0069848 ! RD23A_HUMAN-Phosphoserine128 relationship: transforms_into CCO:B0069849 ! RD23A_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0069850 ! RD23A_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0069851 ! RD23A_HUMAN-Phosphoserine295 relationship: transforms_into CCO:B0069852 ! RD23A_HUMAN-Phosphoserine357 [Term] id: CCO:B0062850 name: Q96AW5_HUMAN def: "QARS protein" [UniProtKB:Q96AW5] xref: EMBL:AAH16634.2 xref: UniProtKB:Q96AW5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022851 ! QARS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015257 ! qars-traf2 physical interaction [Term] id: CCO:B0062851 name: C170L_HUMAN def: "Cep170-like protein" [UniProtKB:Q96L14] xref: EMBL:AAH14590.2 xref: UniProtKB:Q96L14 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022077 ! CEP170L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015258 ! kiaa0470l-lmo3 physical interaction relationship: participates_in CCO:I0015373 ! kiaa0470l-runx1t1 physical interaction relationship: participates_in CCO:I0015672 ! abi3-kiaa0470l physical interaction [Term] id: CCO:B0062852 name: KELL_HUMAN def: "Kell blood group glycoprotein" [UniProtKB:P23276] synonym: "CD238 antigen" EXACT [UniProtKB:P23276] synonym: "EC 3.4.24.-" EXACT [UniProtKB:P23276] xref: EMBL:AAA03192.1 xref: EMBL:AAB33459.1 xref: EMBL:AAB47018.1 xref: EMBL:AAH03135.1 xref: EMBL:AAH50639.1 xref: EMBL:AAK69488.1 xref: EMBL:AAO38053.1 xref: UniProtKB:P23276 xref: UniProtKB:Q96RS8 xref: UniProtKB:Q99885 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022351 ! KEL_human relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000691 ! neprilysin activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003189 ! endothelin-converting enzyme activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015264 ! ewsr1-kel physical interaction [Term] id: CCO:B0062853 name: GNL3L_HUMAN def: "Guanine nucleotide-binding protein-like 3-like protein" [UniProtKB:Q9NVN8] xref: EMBL:AAH11720.1 xref: EMBL:BAA91712.1 xref: EMBL:CAI40396.1 xref: UniProtKB:Q9NVN8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022281 ! GNL3L_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015267 ! gnl3l-ldoc1 physical interaction [Term] id: CCO:B0062854 name: NAGK_HUMAN def: "N-acetyl-D-glucosamine kinase" [UniProtKB:Q9UJ70] synonym: "EC 2.7.1.59" EXACT [UniProtKB:Q9UJ70] synonym: "GlcNAc kinase" EXACT [UniProtKB:Q9UJ70] synonym: "N-acetylglucosamine kinase" EXACT [UniProtKB:Q9UJ70] xref: EMBL:AAH01029.1 xref: EMBL:AAH05371.1 xref: EMBL:AAY14748.1 xref: EMBL:BAA91923.1 xref: EMBL:BAD96365.1 xref: EMBL:CAB61848.1 xref: EMBL:CAG33552.1 xref: UniProtKB:Q53HD5 xref: UniProtKB:Q6IA84 xref: UniProtKB:Q9BS29 xref: UniProtKB:Q9BVP0 xref: UniProtKB:Q9NV37 xref: UniProtKB:Q9UJ70 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022425 ! NAGK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015272 ! dach1-nagk physical interaction relationship: transforms_into CCO:B0068436 ! NAGK_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0068437 ! NAGK_HUMAN-Phosphotyrosine205 [Term] id: CCO:B0062855 name: MFSD3_HUMAN def: "Major facilitator superfamily domain-containing protein 3" [UniProtKB:Q96ES6] xref: EMBL:AAH11982.1 xref: UniProtKB:Q96ES6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022397 ! MFSD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015275 ! mdfi-mfsd3 physical interaction [Term] id: CCO:B0062856 name: F103A_HUMAN def: "Protein FAM103A1" [UniProtKB:Q9BTL3] xref: EMBL:AAH03627.1 xref: EMBL:AAH27181.1 xref: EMBL:AAI12330.1 xref: UniProtKB:Q2M1J8 xref: UniProtKB:Q9BTL3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022234 ! FAM103A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015279 ! c6orf119-pepp2 physical interaction relationship: transforms_into CCO:B0066034 ! F103A_HUMAN-Phosphoserine36 [Term] id: CCO:B0062857 name: MGN2_HUMAN def: "Protein mago nashi homolog 2" [UniProtKB:Q96A72] xref: EMBL:AAF86648.1 xref: EMBL:AAH10905.1 xref: EMBL:BAA91522.1 xref: EMBL:BAB14202.1 xref: UniProtKB:Q96A72 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022399 ! MAGOHB_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015281 ! hmg20a-magoh2 physical interaction [Term] id: CCO:B0062858 name: SNP23_HUMAN def: "Synaptosomal-associated protein 23" [UniProtKB:O00161] synonym: "SNAP-23" EXACT [UniProtKB:O00161] synonym: "Vesicle-membrane fusion protein SNAP-23" EXACT [UniProtKB:O00161] xref: EMBL:AAC50537.1 xref: EMBL:AAH00148.1 xref: EMBL:AAH03686.1 xref: EMBL:AAH22890.1 xref: EMBL:AAP35562.1 xref: EMBL:CAA09864.1 xref: EMBL:CAA70760.1 xref: EMBL:CAA70761.1 xref: EMBL:CAC07504.1 xref: EMBL:CAG33493.1 xref: UniProtKB:O00161 xref: UniProtKB:O00162 xref: UniProtKB:Q13602 xref: UniProtKB:Q6IAE3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022660 ! SNAP23_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0015286 ! abi3-snap23 physical interaction relationship: transforms_into CCO:B0070686 ! SNP23_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0070687 ! SNP23_HUMAN-Phosphoserine110 [Term] id: CCO:B0062859 name: RBM42_HUMAN def: "RNA-binding protein 42" [UniProtKB:Q9BTD8] synonym: "RNA-binding motif protein 42" EXACT [UniProtKB:Q9BTD8] xref: EMBL:AAB57629.1 xref: EMBL:AAH02868.1 xref: EMBL:AAH04204.1 xref: EMBL:AAH31682.1 xref: UniProtKB:O00320 xref: UniProtKB:Q8N5R7 xref: UniProtKB:Q9BTD8 xref: UniProtKB:Q9BU66 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022560 ! RBM42_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015287 ! hnrpk-mgc10433 physical interaction [Term] id: CCO:B0062860 name: Q9BWD7_HUMAN def: "FASTK protein" [UniProtKB:Q9BWD7] xref: EMBL:AAH00377.1 xref: UniProtKB:Q9BWD7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0017765 ! FASTK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015294 ! fastk-mdfi physical interaction [Term] id: CCO:B0062861 name: NCS1_HUMAN def: "Neuronal calcium sensor 1" [UniProtKB:P62166] synonym: "Frequenin homolog" EXACT [UniProtKB:P62166] synonym: "Frequenin-like protein" EXACT [UniProtKB:P62166] synonym: "Frequenin-like ubiquitous protein" EXACT [UniProtKB:P62166] synonym: "NCS-1" EXACT [UniProtKB:P62166] xref: EMBL:AAF01804.1 xref: EMBL:AAH04856.1 xref: EMBL:AAP97256.1 xref: EMBL:CAA58867.1 xref: EMBL:CAI16951.1 xref: UniProtKB:P36610 xref: UniProtKB:P62166 xref: UniProtKB:Q9UK26 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022433 ! FREQ_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001005 ! dendrite relationship: participates_in CCO:I0015299 ! dtx2-freq physical interaction [Term] id: CCO:B0062862 name: AP1M1_HUMAN def: "AP-1 complex subunit mu-1" [UniProtKB:Q9BXS5] synonym: "Adaptor protein complex AP-1 mu-1 subunit" EXACT [UniProtKB:Q9BXS5] synonym: "Adaptor-related protein complex 1 mu-1 subunit" EXACT [UniProtKB:Q9BXS5] synonym: "AP-mu chain family member mu1A" EXACT [UniProtKB:Q9BXS5] synonym: "Clathrin assembly protein complex 1 medium chain 1" EXACT [UniProtKB:Q9BXS5] synonym: "Clathrin coat assembly protein AP47" EXACT [UniProtKB:Q9BXS5] synonym: "Clathrin coat-associated protein AP47" EXACT [UniProtKB:Q9BXS5] synonym: "Golgi adaptor HA1/AP1 adaptin mu-1 subunit" EXACT [UniProtKB:Q9BXS5] synonym: "Mu-adaptin 1" EXACT [UniProtKB:Q9BXS5] synonym: "Mu1A-adaptin" EXACT [UniProtKB:Q9BXS5] xref: EMBL:AAH17469.1 xref: EMBL:AAK28024.1 xref: UniProtKB:Q9BXS5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022037 ! AP1M1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015300 ! ap1m1-mtf1 physical interaction relationship: participates_in CCO:I0015650 ! ap1m1-dvl2 physical interaction relationship: participates_in CCO:I0015773 ! ap1m1-ldoc1 physical interaction relationship: transforms_into CCO:B0065657 ! AP1M1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0065658 ! AP1M1_HUMAN-Phosphothreonine152 relationship: transforms_into CCO:B0065659 ! AP1M1_HUMAN-Phosphothreonine154 [Term] id: CCO:B0062863 name: ZMY10_HUMAN def: "Zinc finger MYND domain-containing protein 10" [UniProtKB:O75800] synonym: "BLu protein" EXACT [UniProtKB:O75800] xref: EMBL:AAB67311.1 xref: EMBL:AAC24726.1 xref: EMBL:AAC24728.1 xref: EMBL:AAH33732.1 xref: EMBL:CAD38688.1 xref: EMBL:EAW65104.1 xref: UniProtKB:A6NK41 xref: UniProtKB:O14570 xref: UniProtKB:O75800 xref: UniProtKB:O75801 xref: UniProtKB:Q8N4R6 xref: UniProtKB:Q8NDN6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022803 ! ZMYND10_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015302 ! tsc22d4-zmynd10 physical interaction relationship: participates_in CCO:I0019414 ! zmynd10-tsc22d4 physical interaction [Term] id: CCO:B0062864 name: HSB11_HUMAN def: "Heat shock protein beta-11" [UniProtKB:Q9Y547] synonym: "Hspb11" EXACT [UniProtKB:Q9Y547] synonym: "Placental protein 25" EXACT [UniProtKB:Q9Y547] synonym: "PP25" EXACT [UniProtKB:Q9Y547] xref: EMBL:AAD43011.1 xref: EMBL:AAH05245.1 xref: EMBL:AAQ03618.1 xref: EMBL:AAQ03994.1 xref: EMBL:EAX06717.1 xref: UniProtKB:A6NG57 xref: UniProtKB:Q9Y547 xref: UniProtKB:Q9Y684 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022320 ! HSPB11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015305 ! c1orf41-rabl4 physical interaction [Term] id: CCO:B0062865 name: S18L1_HUMAN def: "SS18-like protein 1" [UniProtKB:O75177] synonym: "SYT homolog 1" EXACT [UniProtKB:O75177] xref: EMBL:AAH34494.1 xref: EMBL:BAA31668.1 xref: EMBL:CAI18836.1 xref: UniProtKB:O75177 xref: UniProtKB:Q5JXJ3 xref: UniProtKB:Q8NE69 xref: UniProtKB:Q9BR55 xref: UniProtKB:Q9H4K6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022624 ! SS18L1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015307 ! rfxdc1-ss18l1 physical interaction [Term] id: CCO:B0062866 name: CD177_HUMAN def: "CD177 antigen precursor" [UniProtKB:Q8N6Q3] synonym: "CD177 antigen" EXACT [UniProtKB:Q8N6Q3] synonym: "HNA-2a" EXACT [UniProtKB:Q8N6Q3] synonym: "Human neutrophil alloantigen 2a" EXACT [UniProtKB:Q8N6Q3] synonym: "NB1 glycoprotein" EXACT [UniProtKB:Q8N6Q3] synonym: "NB1 GP" EXACT [UniProtKB:Q8N6Q3] synonym: "Polycythemia rubra vera protein 1" EXACT [UniProtKB:Q8N6Q3] synonym: "PRV-1" EXACT [UniProtKB:Q8N6Q3] xref: EMBL:AAG00895.1 xref: EMBL:AAH29167.1 xref: EMBL:AAQ89291.1 xref: EMBL:AAV38914.1 xref: EMBL:CAC44459.1 xref: EMBL:CAC83724.1 xref: EMBL:CAC83758.1 xref: UniProtKB:Q711Q2 xref: UniProtKB:Q8N6Q3 xref: UniProtKB:Q8NCV9 xref: UniProtKB:Q96QH1 xref: UniProtKB:Q9HDA5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022107 ! CD177_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0015315 ! ewsr1-prv1 physical interaction relationship: participates_in CCO:I0015734 ! csen-prv1 physical interaction [Term] id: CCO:B0062867 name: ZN607_HUMAN def: "Zinc finger protein 607" [UniProtKB:Q96SK3] xref: EMBL:AAH14850.1 xref: EMBL:BAB55313.1 xref: UniProtKB:Q96C40 xref: UniProtKB:Q96SK3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022808 ! ZNF607_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015316 ! mdfi-znf607 physical interaction [Term] id: CCO:B0062868 name: DGC6L_HUMAN def: "Protein DGCR6L" [UniProtKB:Q9BY27] synonym: "DiGeorge syndrome critical region 6-like protein" EXACT [UniProtKB:Q9BY27] xref: EMBL:AAH00682.1 xref: EMBL:AAK15585.1 xref: EMBL:CAG30247.1 xref: UniProtKB:Q9BW33 xref: UniProtKB:Q9BY27 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022183 ! DGCR6L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015318 ! dgcr6l-mbip physical interaction [Term] id: CCO:B0062869 name: EMD_HUMAN def: "Emerin" [UniProtKB:P50402] xref: EMBL:AAA92645.1 xref: EMBL:AAH00738.1 xref: EMBL:AAP36065.1 xref: EMBL:BAA10972.1 xref: EMBL:CAA57817.1 xref: EMBL:CAA60500.1 xref: UniProtKB:P50402 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022217 ! EMD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0015323 ! creb3-emd physical interaction relationship: participates_in CCO:I0017678 ! emd-bclaf1-3 physical interaction relationship: participates_in CCO:I0018300 ! emd-bclaf1-1 physical interaction relationship: participates_in CCO:I0018301 ! emd-bclaf1-2 direct interaction relationship: participates_in CCO:I0019404 ! emd-sh3gl2-1 physical interaction relationship: participates_in CCO:I0019986 ! emd-sh3gl2 physical interaction relationship: participates_in CCO:I0019987 ! emd-sh3gl3 physical interaction relationship: transforms_into CCO:B0065992 ! EMD_HUMAN-Phosphoserine49 relationship: transforms_into CCO:B0065993 ! EMD_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0065994 ! EMD_HUMAN-Phosphoserine54 relationship: transforms_into CCO:B0065995 ! EMD_HUMAN-Phosphotyrosine59 relationship: transforms_into CCO:B0065996 ! EMD_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0065997 ! EMD_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0065998 ! EMD_HUMAN-Phosphotyrosine74 relationship: transforms_into CCO:B0065999 ! EMD_HUMAN-Phosphotyrosine85 relationship: transforms_into CCO:B0066000 ! EMD_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0066001 ! EMD_HUMAN-Phosphotyrosine95 relationship: transforms_into CCO:B0066002 ! EMD_HUMAN-Phosphotyrosine99 relationship: transforms_into CCO:B0066003 ! EMD_HUMAN-Phosphotyrosine105 relationship: transforms_into CCO:B0066004 ! EMD_HUMAN-Phosphoserine120 relationship: transforms_into CCO:B0066005 ! EMD_HUMAN-Phosphotyrosine161 relationship: transforms_into CCO:B0066006 ! EMD_HUMAN-Phosphoserine163 relationship: transforms_into CCO:B0066007 ! EMD_HUMAN-Phosphotyrosine167 [Term] id: CCO:B0062870 name: IPO13_HUMAN def: "Importin-13" [UniProtKB:O94829] synonym: "Imp13" EXACT [UniProtKB:O94829] synonym: "Kap13" EXACT [UniProtKB:O94829] synonym: "Karyopherin-13" EXACT [UniProtKB:O94829] synonym: "Ran-binding protein 13" EXACT [UniProtKB:O94829] synonym: "RanBP13" EXACT [UniProtKB:O94829] xref: EMBL:AAF73471.1 xref: EMBL:AAH08194.1 xref: EMBL:BAA34444.2 xref: EMBL:BAB14575.1 xref: EMBL:CAB55966.1 xref: EMBL:CAI16798.1 xref: EMBL:EAX07072.1 xref: UniProtKB:O94829 xref: UniProtKB:Q5T4X3 xref: UniProtKB:Q7LC04 xref: UniProtKB:Q96HS3 xref: UniProtKB:Q9H8N3 xref: UniProtKB:Q9UFR1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022340 ! IPO13_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015328 ! ipo13-pax6 physical interaction relationship: participates_in CCO:I0015631 ! cart1-ipo13 physical interaction relationship: participates_in CCO:I0019409 ! cart1-cart1 physical interaction [Term] id: CCO:B0062871 name: SPY2_HUMAN def: "Protein sprouty homolog 2" [UniProtKB:O43597] synonym: "Spry-2" EXACT [UniProtKB:O43597] xref: EMBL:AAC04258.1 xref: EMBL:AAH15745.1 xref: EMBL:CAD28524.1 xref: EMBL:CAI14911.1 xref: UniProtKB:O43597 xref: UniProtKB:Q5T6Z7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022673 ! SPRY2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015333 ! spry2-traf2 physical interaction [Term] id: CCO:B0062872 name: IMP3_HUMAN def: "U3 small nucleolar ribonucleoprotein protein IMP3" [UniProtKB:Q9NV31] synonym: "BRMS2" EXACT [UniProtKB:Q9NV31] synonym: "U3 snoRNP protein IMP3" EXACT [UniProtKB:Q9NV31] xref: EMBL:AAH06487.1 xref: EMBL:AAH11745.1 xref: EMBL:AAL06639.1 xref: EMBL:BAA91929.1 xref: EMBL:BAD96841.1 xref: EMBL:CAB66847.1 xref: UniProtKB:Q53G10 xref: UniProtKB:Q9NV31 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022338 ! IMP3_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0015341 ! imp3-lpxn physical interaction [Term] id: CCO:B0062873 name: LIMS1_HUMAN def: "LIM and senescent cell antigen-like-containing domain protein 1" [UniProtKB:P48059] synonym: "Particularly interesting new Cys-His protein 1" EXACT [UniProtKB:P48059] synonym: "PINCH-1" EXACT [UniProtKB:P48059] synonym: "Renal carcinoma antigen NY-REN-48" EXACT [UniProtKB:P48059] xref: EMBL:AAA20086.2 xref: EMBL:AAH05341.1 xref: EMBL:AAY14983.1 xref: UniProtKB:P48059 xref: UniProtKB:Q53TE0 xref: UniProtKB:Q9BS44 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011822 ! LIMS1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: participates_in CCO:I0015349 ! lims1-lpxn physical interaction relationship: transforms_into CCO:B0067673 ! LIMS1_HUMAN-N-acetylalanine2 [Term] id: CCO:B0062874 name: TRI31_HUMAN def: "Tripartite motif-containing protein 31" [UniProtKB:Q9BZY9] xref: EMBL:AAG50165.1 xref: EMBL:AAG50166.1 xref: EMBL:AAH16866.1 xref: EMBL:AAH17017.1 xref: EMBL:AAP35321.1 xref: EMBL:BAD96449.1 xref: EMBL:CAA69165.1 xref: EMBL:CAI17583.1 xref: EMBL:CAI18183.1 xref: EMBL:CAI18447.1 xref: UniProtKB:A6NLX6 xref: UniProtKB:Q53H52 xref: UniProtKB:Q5RI37 xref: UniProtKB:Q5SRJ7 xref: UniProtKB:Q5SRJ8 xref: UniProtKB:Q5SS28 xref: UniProtKB:Q96AK4 xref: UniProtKB:Q96AP8 xref: UniProtKB:Q99579 xref: UniProtKB:Q9BZY8 xref: UniProtKB:Q9BZY9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022734 ! TRIM31_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015350 ! traf2-trim31 physical interaction [Term] id: CCO:B0062875 name: NOL4_HUMAN def: "Nucleolar protein 4" [UniProtKB:O94818] synonym: "Nucleolar-localized protein" EXACT [UniProtKB:O94818] xref: EMBL:AAH00313.1 xref: EMBL:AAP35409.1 xref: EMBL:BAA34576.1 xref: EMBL:BAA34797.1 xref: UniProtKB:O94818 xref: UniProtKB:Q9BWF1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022449 ! NOL4_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: participates_in CCO:I0015354 ! ctbp2-nol4 physical interaction relationship: participates_in CCO:I0015817 ! nol4-snapc5 physical interaction relationship: participates_in CCO:I0020608 ! nol4-hrmt1l2 physical interaction [Term] id: CCO:B0062876 name: PARVA_HUMAN def: "Alpha-parvin" [UniProtKB:Q9NVD7] synonym: "Actopaxin" EXACT [UniProtKB:Q9NVD7] synonym: "Calponin-like integrin-linked kinase-binding protein" EXACT [UniProtKB:Q9NVD7] synonym: "CH-ILKBP" EXACT [UniProtKB:Q9NVD7] synonym: "Matrix-remodeling-associated protein 2" EXACT [UniProtKB:Q9NVD7] xref: EMBL:AAG27173.1 xref: EMBL:AAH14535.1 xref: EMBL:AAH16713.1 xref: EMBL:AAK49911.1 xref: EMBL:BAA91815.1 xref: EMBL:BAB14009.1 xref: UniProtKB:Q96C85 xref: UniProtKB:Q9HA48 xref: UniProtKB:Q9NVD7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022492 ! PARVA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015356 ! ilk-parva physical interaction relationship: transforms_into CCO:B0069115 ! PARVA_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0069117 ! PARVA_HUMAN-Phosphothreonine36 [Term] id: CCO:B0062877 name: Q8TBE5_HUMAN def: "Zinc finger protein Pegasus (IKAROS family zinc finger protein 5)." [UniProtKB:Q8TBE5] xref: EMBL:AAH22564.1 xref: UniProtKB:Q8TBE5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0018246 ! IKZF5_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0015364 ! ldoc1-znfn1a5 physical interaction [Term] id: CCO:B0062878 name: CXAR_HUMAN def: "Coxsackievirus and adenovirus receptor precursor" [UniProtKB:P78310] synonym: "Coxsackievirus B-adenovirus receptor" EXACT [UniProtKB:P78310] synonym: "CVB3-binding protein" EXACT [UniProtKB:P78310] synonym: "hCAR" EXACT [UniProtKB:P78310] synonym: "HCVADR" EXACT [UniProtKB:P78310] xref: EMBL:AAC51234.1 xref: EMBL:AAD31772.1 xref: EMBL:AAF05908.1 xref: EMBL:AAF24344.1 xref: EMBL:AAG01088.1 xref: EMBL:AAH03684.1 xref: EMBL:AAH10536.1 xref: EMBL:AAL68878.1 xref: EMBL:AAL68879.1 xref: EMBL:AAL68880.1 xref: EMBL:AAV38679.1 xref: EMBL:CAA68868.1 xref: UniProtKB:O00694 xref: UniProtKB:P78310 xref: UniProtKB:Q8WWT6 xref: UniProtKB:Q8WWT7 xref: UniProtKB:Q8WWT8 xref: UniProtKB:Q9UKV4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022166 ! CXADR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015375 ! cxadr-ewsr1 physical interaction relationship: transforms_into CCO:B0065917 ! CXAR_HUMAN-Phosphoserine293 relationship: transforms_into CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: transforms_into CCO:B0065919 ! CXAR_HUMAN-Phosphoserine306 relationship: transforms_into CCO:B0065920 ! CXAR_HUMAN-Phosphoserine323 relationship: transforms_into CCO:B0065921 ! CXAR_HUMAN-Phosphoserine332 [Term] id: CCO:B0062879 name: CTSR1_HUMAN def: "Cation channel sperm-associated protein 1" [UniProtKB:Q8NEC5] synonym: "CatSper1" EXACT [UniProtKB:Q8NEC5] synonym: "hCatSper" EXACT [UniProtKB:Q8NEC5] xref: EMBL:AAH32950.1 xref: EMBL:AAH36522.1 xref: EMBL:AAL14105.1 xref: UniProtKB:Q8NEC5 xref: UniProtKB:Q96P76 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022161 ! CATSPER1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0015379 ! catsper1-trip6 physical interaction relationship: participates_in CCO:I0015501 ! catsper1-mdfi physical interaction [Term] id: CCO:B0062880 name: THAP1_HUMAN def: "THAP domain-containing protein 1" [UniProtKB:Q9NVV9] xref: EMBL:AAH21721.1 xref: EMBL:BAA91635.1 xref: EMBL:BAD96951.1 xref: EMBL:CAG33537.1 xref: UniProtKB:Q53FQ1 xref: UniProtKB:Q6IA99 xref: UniProtKB:Q9NVV9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022710 ! THAP1_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015382 ! thap1-znf408 physical interaction relationship: participates_in CCO:I0015655 ! nup62-thap1 physical interaction relationship: participates_in CCO:I0015812 ! dvl2-thap1 physical interaction [Term] id: CCO:B0062881 name: TPGS2_HUMAN def: "Tubulin polyglutamylase complex subunit 2" [UniProtKB:Q68CL5] synonym: "PGs2" EXACT [UniProtKB:Q68CL5] xref: EMBL:AAH15178.2 xref: EMBL:AAH22199.2 xref: EMBL:AAH87845.1 xref: EMBL:AAT06747.1 xref: EMBL:BAD38633.1 xref: EMBL:CAB43322.2 xref: UniProtKB:Q4KN59 xref: UniProtKB:Q68CL5 xref: UniProtKB:Q8WTU3 xref: UniProtKB:Q96BT9 xref: UniProtKB:Q9Y435 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022727 ! C18orf10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0015385 ! c18orf10-ewsr1 physical interaction [Term] id: CCO:B0062882 name: PRR14_HUMAN def: "Proline-rich protein 14" [UniProtKB:Q9BWN1] xref: EMBL:AAH00119.1 xref: EMBL:AAH21934.1 xref: EMBL:AAH50677.1 xref: EMBL:BAC11207.1 xref: EMBL:EAW52222.1 xref: UniProtKB:Q8WTX2 xref: UniProtKB:Q9BWN1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022535 ! PRR14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015389 ! cbx5-mgc3121 physical interaction [Term] id: CCO:B0062883 name: CB065_HUMAN def: "Uncharacterized protein C2orf65" [UniProtKB:Q8TC57] xref: EMBL:AAH14602.1 xref: EMBL:AAH25997.1 xref: EMBL:AAX93225.1 xref: EMBL:BAC85295.1 xref: EMBL:EAW99611.1 xref: UniProtKB:Q6ZP30 xref: UniProtKB:Q8TC57 xref: UniProtKB:Q96L07 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022091 ! C2orf65_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015390 ! crx-loc130951 physical interaction [Term] id: CCO:B0062884 name: VASP_HUMAN def: "Vasodilator-stimulated phosphoprotein" [UniProtKB:P50552] synonym: "VASP" EXACT [UniProtKB:P50552] xref: EMBL:AAH26019.1 xref: EMBL:AAH38224.1 xref: EMBL:CAA67147.2 xref: EMBL:CAA86523.1 xref: UniProtKB:P50552 xref: UniProtKB:Q6PIZ1 xref: UniProtKB:Q93035 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022772 ! VASP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015395 ! nol3-vasp physical interaction relationship: transforms_into CCO:B0071777 ! VASP_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0071778 ! VASP_HUMAN-Phosphotyrosine39 relationship: transforms_into CCO:B0071779 ! VASP_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0071780 ! VASP_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0071781 ! VASP_HUMAN-Phosphothreonine278 relationship: transforms_into CCO:B0071782 ! VASP_HUMAN-Phosphothreonine316 relationship: transforms_into CCO:B0071783 ! VASP_HUMAN-Phosphoserine322 relationship: transforms_into CCO:B0071784 ! VASP_HUMAN-Phosphoserine323 [Term] id: CCO:B0062885 name: RL9_HUMAN def: "60S ribosomal protein L9" [UniProtKB:P32969] xref: EMBL:AAA63752.1 xref: EMBL:AAB01040.1 xref: EMBL:AAB01041.1 xref: EMBL:AAH00483.1 xref: EMBL:AAH04156.1 xref: EMBL:AAH04206.1 xref: EMBL:AAH07967.1 xref: EMBL:AAH12149.1 xref: EMBL:AAH31906.1 xref: EMBL:AAH66318.1 xref: EMBL:AAH70214.1 xref: EMBL:BAA03401.1 xref: EMBL:BAA25830.1 xref: EMBL:BAB93494.1 xref: UniProtKB:P32969 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022582 ! RPL9_human relationship: encoded_by CCO:G0022583 ! RPL9P7_human relationship: encoded_by CCO:G0022584 ! RPL9P8_human relationship: encoded_by CCO:G0022585 ! RPL9P9_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0015397 ! dhps-rpl9 physical interaction [Term] id: CCO:B0062886 name: Q8N656_HUMAN def: "SALL2 protein" [UniProtKB:Q8N656] xref: EMBL:AAH24245.1 xref: EMBL:AAH90958.1 xref: UniProtKB:Q8N656 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0019833 ! SALL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015400 ! sall2-zimp7 physical interaction relationship: participates_in CCO:I0015771 ! ewsr1-sall2 physical interaction [Term] id: CCO:B0062887 name: CETP_HUMAN def: "Cholesteryl ester transfer protein precursor" [UniProtKB:P11597] synonym: "Lipid transfer protein I" EXACT [UniProtKB:P11597] xref: EMBL:AAA51977.1 xref: EMBL:AAA51978.1 xref: EMBL:AAB59388.1 xref: EMBL:AAB86604.1 xref: EMBL:AAD14876.1 xref: EMBL:AAH25739.1 xref: UniProtKB:P11597 xref: UniProtKB:Q13987 xref: UniProtKB:Q13988 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022115 ! CETP_human relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001671 ! phospholipid transporter activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0002880 ! cholesterol binding relationship: has_function CCO:F0003584 ! cholesterol transporter activity relationship: has_function CCO:F0003586 ! triglyceride binding relationship: has_function CCO:F0004640 ! phosphatidylcholine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0001374 ! vesicle relationship: located_in CCO:C0002144 ! high-density lipoprotein particle relationship: participates_in CCO:I0015405 ! cetp-ewsr1 physical interaction relationship: participates_in CCO:I0020510 ! arpc3-cetp physical interaction [Term] id: CCO:B0062888 name: NDUV1_HUMAN def: "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor" [UniProtKB:P49821] synonym: "CI-51kD" EXACT [UniProtKB:P49821] synonym: "Complex I-51kD" EXACT [UniProtKB:P49821] synonym: "EC 1.6.5.3" EXACT [UniProtKB:P49821] synonym: "EC 1.6.99.3" EXACT [UniProtKB:P49821] synonym: "NADH dehydrogenase flavoprotein 1" EXACT [UniProtKB:P49821] synonym: "NADH-ubiquinone oxidoreductase 51 kDa subunit" EXACT [UniProtKB:P49821] xref: EMBL:AAB24883.1 xref: EMBL:AAB29698.2 xref: EMBL:AAC39722.1 xref: EMBL:AAC39750.1 xref: EMBL:AAD40373.1 xref: EMBL:AAH08146.1 xref: EMBL:AAH15645.1 xref: EMBL:CAA76757.1 xref: UniProtKB:O60924 xref: UniProtKB:O60940 xref: UniProtKB:P49821 xref: UniProtKB:Q16104 xref: UniProtKB:Q96BF8 xref: UniProtKB:Q96HS7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022441 ! NDUFV1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015409 ! ewsr1-ndufv1 physical interaction relationship: transforms_into CCO:B0068554 ! NDUV1_HUMAN-N6-acetyllysine81 relationship: transforms_into CCO:B0068555 ! NDUV1_HUMAN-N6-acetyllysine104 relationship: transforms_into CCO:B0068556 ! NDUV1_HUMAN-N6-acetyllysine375 [Term] id: CCO:B0062889 name: RNPS1_HUMAN def: "RNA-binding protein with serine-rich domain 1" [UniProtKB:Q15287] synonym: "SR-related protein LDC2" EXACT [UniProtKB:Q15287] xref: EMBL:AAA92859.1 xref: EMBL:AAC39791.1 xref: EMBL:AAF72519.1 xref: EMBL:AAH01659.1 xref: EMBL:AAH01838.1 xref: EMBL:AAI08317.1 xref: EMBL:AAL56665.1 xref: UniProtKB:O75308 xref: UniProtKB:Q15287 xref: UniProtKB:Q32P25 xref: UniProtKB:Q8WY42 xref: UniProtKB:Q9NYG3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022594 ! RNPS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015411 ! dvl2-rnps1 physical interaction relationship: transforms_into CCO:B0070108 ! RNPS1_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0070109 ! RNPS1_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0070110 ! RNPS1_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0070111 ! RNPS1_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0070112 ! RNPS1_HUMAN-Phosphoserine157 relationship: transforms_into CCO:B0070113 ! RNPS1_HUMAN-Phosphotyrosine205 relationship: transforms_into CCO:B0070114 ! RNPS1_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0070115 ! RNPS1_HUMAN-Phosphoserine266 relationship: transforms_into CCO:B0070116 ! RNPS1_HUMAN-Phosphoserine287 relationship: transforms_into CCO:B0070117 ! RNPS1_HUMAN-Phosphoserine289 [Term] id: CCO:B0062890 name: CPSF7_HUMAN def: "Cleavage and polyadenylation specificity factor subunit 7" [UniProtKB:Q8N684] synonym: "Cleavage and polyadenylation specificity factor 59 kDa subunit" EXACT [UniProtKB:Q8N684] synonym: "CPSF 59 kDa subunit" EXACT [UniProtKB:Q8N684] synonym: "Pre-mRNA cleavage factor Im 59 kDa subunit" EXACT [UniProtKB:Q8N684] xref: EMBL:AAH18135.1 xref: EMBL:BAB14118.1 xref: EMBL:CAC21678.1 xref: EMBL:CAC81661.1 xref: EMBL:CAD97884.1 xref: UniProtKB:Q7Z3H9 xref: UniProtKB:Q8N684 xref: UniProtKB:Q9H025 xref: UniProtKB:Q9H9V1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022151 ! CPSF7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015416 ! dvl2-flj12529 physical interaction relationship: participates_in CCO:I0015636 ! flj12529-hrmt1l1 physical interaction relationship: participates_in CCO:I0015654 ! ewsr1-flj12529 physical interaction relationship: participates_in CCO:I0015816 ! flj12529-nck2 physical interaction relationship: participates_in CCO:I0016165 ! atxn1-flj12529 physical interaction relationship: participates_in CCO:I0017629 ! atxn1-flj12529-1 physical interaction relationship: transforms_into CCO:B0065894 ! CPSF7_HUMAN-Phosphotyrosine72 relationship: transforms_into CCO:B0065895 ! CPSF7_HUMAN-Phosphothreonine73 relationship: transforms_into CCO:B0065896 ! CPSF7_HUMAN-Phosphoserine197 relationship: transforms_into CCO:B0065897 ! CPSF7_HUMAN-Phosphothreonine203 relationship: transforms_into CCO:B0065898 ! CPSF7_HUMAN-Phosphoserine413 relationship: transforms_into CCO:B0065899 ! CPSF7_HUMAN-Phosphoserine423 relationship: transforms_into CCO:B0065900 ! CPSF7_HUMAN-Phosphoserine429 [Term] id: CCO:B0062891 name: C43BP_HUMAN def: "Collagen type IV alpha-3-binding protein" [UniProtKB:Q9Y5P4] synonym: "Ceramide transfer protein" EXACT [UniProtKB:Q9Y5P4] synonym: "Goodpasture antigen-binding protein" EXACT [UniProtKB:Q9Y5P4] synonym: "GPBP" EXACT [UniProtKB:Q9Y5P4] synonym: "hCERT" EXACT [UniProtKB:Q9Y5P4] synonym: "StAR-related lipid transfer protein 11" EXACT [UniProtKB:Q9Y5P4] synonym: "StARD11" EXACT [UniProtKB:Q9Y5P4] synonym: "START domain-containing protein 11" EXACT [UniProtKB:Q9Y5P4] xref: EMBL:AAD30288.1 xref: EMBL:AAG42046.1 xref: EMBL:AAG42051.1 xref: EMBL:AAH00102.1 xref: EMBL:AAR26717.1 xref: EMBL:AAR26718.1 xref: EMBL:BAB58974.1 xref: EMBL:BAB58977.1 xref: EMBL:BAC03762.1 xref: UniProtKB:Q53YV1 xref: UniProtKB:Q53YV2 xref: UniProtKB:Q96Q85 xref: UniProtKB:Q96Q88 xref: UniProtKB:Q9H2S7 xref: UniProtKB:Q9H2S8 xref: UniProtKB:Q9Y5P4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022079 ! COL4A3BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015422 ! col4a3bp-csnk1g2 physical interaction relationship: participates_in CCO:I0015632 ! col4a3bp-itgb3bp physical interaction relationship: participates_in CCO:I0015809 ! col4a3bp-rtn4 physical interaction relationship: transforms_into CCO:B0065802 ! C43BP_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0065803 ! C43BP_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0065804 ! C43BP_HUMAN-Phosphoserine377 relationship: transforms_into CCO:B0065805 ! C43BP_HUMAN-Phosphoserine380 relationship: transforms_into CCO:B0065806 ! C43BP_HUMAN-Phosphoserine611 [Term] id: CCO:B0062892 name: RO52_HUMAN def: "52 kDa Ro protein" [UniProtKB:P19474] synonym: "52 kDa ribonucleoprotein autoantigen Ro/SS-A" EXACT [UniProtKB:P19474] synonym: "RING finger protein 81" EXACT [UniProtKB:P19474] synonym: "Ro(SS-A)" EXACT [UniProtKB:P19474] synonym: "Sjoegren syndrome type A antigen" EXACT [UniProtKB:P19474] synonym: "SS-A" EXACT [UniProtKB:P19474] synonym: "Tripartite motif-containing protein 21" EXACT [UniProtKB:P19474] xref: EMBL:AAA36581.1 xref: EMBL:AAA36651.1 xref: EMBL:AAA79867.1 xref: EMBL:AAB87094.1 xref: EMBL:AAH10861.1 xref: EMBL:AAK76432.1 xref: UniProtKB:P19474 xref: UniProtKB:Q96RF8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022596 ! TRIM21_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0015423 ! nif3l1-trim21 physical interaction relationship: participates_in CCO:I0018211 ! ncoa3-crebbp-ncoa2-1 physical interaction relationship: participates_in CCO:I0018213 ! ncoa1-ncoa2-crebbp physical interaction [Term] id: CCO:B0062893 name: SAM50_HUMAN def: "Sorting and assembly machinery component 50 homolog" [UniProtKB:Q9Y512] xref: EMBL:AAD34046.1 xref: EMBL:AAH07830.1 xref: EMBL:AAH11681.1 xref: EMBL:AAH15200.1 xref: EMBL:BAA91498.1 xref: EMBL:CAB51401.1 xref: EMBL:CAG30369.1 xref: UniProtKB:Q969Y9 xref: UniProtKB:Q96I46 xref: UniProtKB:Q9NW85 xref: UniProtKB:Q9UQM9 xref: UniProtKB:Q9Y512 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022634 ! SAMM50_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: participates_in CCO:I0015425 ! meox2-samm50 physical interaction [Term] id: CCO:B0062894 name: CHM2B_HUMAN def: "Charged multivesicular body protein 2b" [UniProtKB:Q9UQN3] synonym: "CHMP2.5" EXACT [UniProtKB:Q9UQN3] synonym: "CHMP2b" EXACT [UniProtKB:Q9UQN3] synonym: "Chromatin-modifying protein 2b" EXACT [UniProtKB:Q9UQN3] synonym: "hVps2-2" EXACT [UniProtKB:Q9UQN3] synonym: "Vacuolar protein-sorting-associated protein 2-2" EXACT [UniProtKB:Q9UQN3] synonym: "Vps2-2" EXACT [UniProtKB:Q9UQN3] xref: EMBL:AAD34079.1 xref: EMBL:AAH01553.1 xref: EMBL:BAD96374.1 xref: EMBL:CAB45721.1 xref: EMBL:CAG38487.1 xref: UniProtKB:Q53HC7 xref: UniProtKB:Q9UQN3 xref: UniProtKB:Q9Y4U6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022122 ! CHMP2B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015428 ! chmp2b-traf2 physical interaction relationship: transforms_into CCO:B0065856 ! CHM2B_HUMAN-Phosphoserine199 [Term] id: CCO:B0062895 name: CK068_HUMAN def: "Uncharacterized protein C11orf68" [UniProtKB:Q9H3H3] synonym: "Basophilic leukemia-expressed protein Bles03" EXACT [UniProtKB:Q9H3H3] synonym: "Protein p5326" EXACT [UniProtKB:Q9H3H3] xref: EMBL:AAG43171.1 xref: EMBL:AAH04414.1 xref: EMBL:AAH10512.1 xref: EMBL:AAH13185.1 xref: UniProtKB:Q9BT13 xref: UniProtKB:Q9H3H3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022131 ! C11orf68_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015429 ! bles03-wbscr1 physical interaction relationship: participates_in CCO:I0020391 ! bles03-sh3gl3 physical interaction [Term] id: CCO:B0062896 name: ZMY19_HUMAN def: "Zinc finger MYND domain-containing protein 19" [UniProtKB:Q96E35] synonym: "MCH-R1-interacting zinc finger protein" EXACT [UniProtKB:Q96E35] synonym: "Melanin-concentrating hormone receptor 1-interacting zinc finger protein" EXACT [UniProtKB:Q96E35] xref: EMBL:AAH12948.1 xref: EMBL:CAC16691.1 xref: EMBL:CAI14585.1 xref: UniProtKB:Q5T366 xref: UniProtKB:Q96E35 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022804 ! ZMYND19_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: participates_in CCO:I0015441 ! kctd13-zmynd19 physical interaction [Term] id: CCO:B0062897 name: DDX39_HUMAN def: "ATP-dependent RNA helicase DDX39" [UniProtKB:O00148] synonym: "DEAD box protein 39" EXACT [UniProtKB:O00148] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O00148] synonym: "Nuclear RNA helicase URH49" EXACT [UniProtKB:O00148] xref: EMBL:AAB50231.1 xref: EMBL:AAH01009.1 xref: EMBL:BAB15509.1 xref: UniProtKB:O00148 xref: UniProtKB:Q9BVP6 xref: UniProtKB:Q9H5W0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022177 ! DDX39_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015446 ! ddx39-hcc1 physical interaction [Term] id: CCO:B0062898 name: Q9BU74_HUMAN def: "ZNF434 protein" [UniProtKB:Q9BU74] xref: EMBL:AAH02859.1 xref: UniProtKB:Q9BU74 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0020748 ! ZNF434_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015448 ! scand1-znf434 physical interaction relationship: participates_in CCO:I0015498 ! znf167-znf434 physical interaction relationship: participates_in CCO:I0015554 ! znf24-znf434 physical interaction [Term] id: CCO:B0062899 name: GCSH_HUMAN def: "Glycine cleavage system H protein, mitochondrial precursor" [UniProtKB:P23434] xref: EMBL:AAA36011.1 xref: EMBL:AAH00790.1 xref: EMBL:AAH20922.1 xref: EMBL:AAP50260.1 xref: EMBL:BAA00625.1 xref: UniProtKB:P23434 xref: UniProtKB:Q9H1E9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022270 ! GCSH_human relationship: has_function CCO:F0000523 ! aminomethyltransferase activity relationship: has_function CCO:F0004659 ! lipoic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000507 ! glycine cleavage complex relationship: participates_in CCO:I0015450 ! gcsh-nmi physical interaction relationship: participates_in CCO:I0020008 ! gcsh-ing5 physical interaction [Term] id: CCO:B0062900 name: PHIPL_HUMAN def: "Phytanoyl-CoA hydroxylase-interacting protein-like" [UniProtKB:Q96FC7] xref: EMBL:AAH11268.2 xref: EMBL:AAQ88529.1 xref: EMBL:BAB47425.1 xref: EMBL:BAB70832.1 xref: EMBL:CAB97028.1 xref: EMBL:CAD39006.1 xref: EMBL:CAH18267.1 xref: EMBL:EAW54185.1 xref: UniProtKB:Q68DF3 xref: UniProtKB:Q6UXY3 xref: UniProtKB:Q8N3W3 xref: UniProtKB:Q96FC7 xref: UniProtKB:Q96JM9 xref: UniProtKB:Q96NP7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022510 ! PHYHIPL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015453 ! pde9a-phyhipl physical interaction [Term] id: CCO:B0062901 name: MR1L1_HUMAN def: "MORF4 family-associated protein 1-like 1" [UniProtKB:Q96HT8] xref: EMBL:AAF67011.1 xref: EMBL:AAG23794.1 xref: EMBL:AAH08087.1 xref: EMBL:AAH66897.1 xref: EMBL:EAW82383.1 xref: UniProtKB:Q6NXT8 xref: UniProtKB:Q96HT8 xref: UniProtKB:Q9P0J5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022407 ! MRFAP1L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015455 ! morf4l1-mrfap1l1 physical interaction [Term] id: CCO:B0062902 name: NPDC1_HUMAN def: "Neural proliferation differentiation and control protein 1 precursor" [UniProtKB:Q9NQX5] synonym: "NPDC-1" EXACT [UniProtKB:Q9NQX5] xref: EMBL:AAF76225.1 xref: EMBL:AAF82603.1 xref: EMBL:AAH04217.1 xref: EMBL:AAK27328.1 xref: EMBL:CAB43321.1 xref: EMBL:CAI12775.1 xref: UniProtKB:Q5SPY8 xref: UniProtKB:Q9BTD6 xref: UniProtKB:Q9BXT3 xref: UniProtKB:Q9NQS2 xref: UniProtKB:Q9NQX5 xref: UniProtKB:Q9Y434 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022452 ! NPDC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015457 ! hnrpk-npdc1 physical interaction relationship: participates_in CCO:I0015530 ! mdfi-npdc1 physical interaction [Term] id: CCO:B0062903 name: UBP2_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 2" [UniProtKB:O75604] synonym: "41 kDa ubiquitin-specific protease" EXACT [UniProtKB:O75604] synonym: "Deubiquitinating enzyme 2" EXACT [UniProtKB:O75604] synonym: "EC 3.1.2.15" EXACT [UniProtKB:O75604] synonym: "Ubiquitin thioesterase 2" EXACT [UniProtKB:O75604] synonym: "Ubiquitin-specific-processing protease 2" EXACT [UniProtKB:O75604] xref: EMBL:AAC28392.1 xref: EMBL:AAH02854.1 xref: EMBL:AAH02955.1 xref: EMBL:BAB71388.1 xref: UniProtKB:O75604 xref: UniProtKB:Q96MB9 xref: UniProtKB:Q9BQ21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022762 ! USP2_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015464 ! traf2-usp2 physical interaction [Term] id: CCO:B0062904 name: TRI41_HUMAN def: "Tripartite motif-containing protein 41" [UniProtKB:Q8WV44] xref: EMBL:AAG23782.1 xref: EMBL:AAH04956.1 xref: EMBL:AAH09762.2 xref: EMBL:AAH18765.2 xref: EMBL:AAH71887.1 xref: EMBL:AAH90953.1 xref: EMBL:BAB70617.1 xref: EMBL:BAD07472.1 xref: EMBL:BAD07473.1 xref: EMBL:CAG33630.1 xref: UniProtKB:Q5BKT0 xref: UniProtKB:Q7L484 xref: UniProtKB:Q8WV44 xref: UniProtKB:Q96Q10 xref: UniProtKB:Q9BSL8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022736 ! TRIM41_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015468 ! trim41-znf263 physical interaction relationship: participates_in CCO:I0015714 ! trim41-znf473 physical interaction relationship: participates_in CCO:I0020602 ! mpp3-trim41 physical interaction relationship: transforms_into CCO:B0071561 ! TRI41_HUMAN-Phosphoserine447 [Term] id: CCO:B0062905 name: CEP72_HUMAN def: "Centrosomal protein of 72 kDa" [UniProtKB:Q9P209] synonym: "Cep72" EXACT [UniProtKB:Q9P209] xref: EMBL:AAH00132.1 xref: EMBL:AAH01750.1 xref: EMBL:BAA91685.1 xref: EMBL:BAA96043.1 xref: UniProtKB:Q9BV03 xref: UniProtKB:Q9BWM3 xref: UniProtKB:Q9NVR4 xref: UniProtKB:Q9P209 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022114 ! CEP72_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015469 ! cep72-znf417 physical interaction relationship: transforms_into CCO:B0065855 ! CEP72_HUMAN-Phosphoserine237 [Term] id: CCO:B0062906 name: SERP2_HUMAN def: "Stress-associated endoplasmic reticulum protein 2" [UniProtKB:Q8N6R1] synonym: "Ribosome-associated membrane protein RAMP4-2" EXACT [UniProtKB:Q8N6R1] xref: EMBL:AAH29067.1 xref: EMBL:CAI12995.1 xref: UniProtKB:Q8N6R1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022642 ! SERP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015477 ! c13orf21-ewsr1 physical interaction [Term] id: CCO:B0062907 name: DYDC2_HUMAN def: "DPY30 domain-containing protein 2" [UniProtKB:Q96IM9] xref: EMBL:AAH07374.1 xref: EMBL:BAC04148.1 xref: EMBL:CAI13698.1 xref: EMBL:CAI13703.1 xref: EMBL:CAI13704.1 xref: UniProtKB:Q5QP07 xref: UniProtKB:Q5QP11 xref: UniProtKB:Q96IM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022200 ! DYDC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015478 ! mgc16186-nme5 physical interaction [Term] id: CCO:B0062908 name: HPCL1_HUMAN def: "Hippocalcin-like protein 1" [UniProtKB:P37235] synonym: "Calcium-binding protein BDR-1" EXACT [UniProtKB:P37235] synonym: "HLP2" EXACT [UniProtKB:P37235] synonym: "VILIP-3" EXACT [UniProtKB:P37235] synonym: "Visinin-like protein 3" EXACT [UniProtKB:P37235] xref: EMBL:AAH09846.1 xref: EMBL:AAH17028.1 xref: EMBL:AAH17482.1 xref: EMBL:BAA03754.1 xref: UniProtKB:P37235 xref: UniProtKB:Q969S5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022314 ! HPCAL1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015480 ! dtx2-hpcal1 physical interaction relationship: participates_in CCO:I0015682 ! hmg20a-hpcal1 physical interaction relationship: participates_in CCO:I0018995 ! atxn1-hpcal1 physical interaction [Term] id: CCO:B0062909 name: RLP24_HUMAN def: "Probable ribosome biogenesis protein RLP24" [UniProtKB:Q9UHA3] synonym: "Ribosomal protein L24-like" EXACT [UniProtKB:Q9UHA3] xref: EMBL:AAF17241.1 xref: EMBL:AAF86651.1 xref: EMBL:AAG43138.1 xref: EMBL:AAH08409.1 xref: EMBL:AAH08422.1 xref: EMBL:AAH08449.1 xref: EMBL:AAH08499.1 xref: EMBL:AAH09593.1 xref: EMBL:AAH09604.1 xref: EMBL:AAH12913.1 xref: EMBL:AAH14576.1 xref: EMBL:AAH16312.1 xref: EMBL:AAH16331.1 xref: EMBL:AAH16725.1 xref: EMBL:AAH16777.1 xref: EMBL:AAH26266.1 xref: EMBL:AAH26267.1 xref: EMBL:AAH28672.1 xref: EMBL:AAH35995.1 xref: EMBL:AAH93067.1 xref: EMBL:AAK26249.1 xref: EMBL:CAG33460.1 xref: UniProtKB:Q561V8 xref: UniProtKB:Q8N6S8 xref: UniProtKB:Q96B04 xref: UniProtKB:Q96C76 xref: UniProtKB:Q96HJ1 xref: UniProtKB:Q9UHA3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022586 ! C15orf15_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000407 ! ribosome relationship: participates_in CCO:I0015481 ! c15orf15-dnmt3l physical interaction [Term] id: CCO:B0062910 name: FATE1_HUMAN def: "Fetal and adult testis-expressed transcript protein" [UniProtKB:Q969F0] synonym: "Cancer/testis antigen 43" EXACT [UniProtKB:Q969F0] synonym: "CT43" EXACT [UniProtKB:Q969F0] synonym: "Tumor antigen BJ-HCC-2" EXACT [UniProtKB:Q969F0] xref: EMBL:AAH22064.1 xref: EMBL:AAK69024.1 xref: EMBL:AAM48744.1 xref: EMBL:BAB71454.1 xref: UniProtKB:Q969F0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022252 ! FATE1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015482 ! fate1-traf2 physical interaction relationship: participates_in CCO:I0017591 ! fate1-tbp physical interaction [Term] id: CCO:B0062911 name: YE036_HUMAN def: "Putative uncharacterized protein LOC116349 precursor" [UniProtKB:Q8N2X6] xref: EMBL:AAH14011.2 xref: EMBL:AAH29796.1 xref: UniProtKB:Q8N2X6 xref: UniProtKB:Q96CR9 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015484 ! q8n2x6-traf2 physical interaction relationship: participates_in CCO:I0015765 ! q8n2x6-trip6 physical interaction [Term] id: CCO:B0062912 name: PRPF3_HUMAN def: "U4/U6 small nuclear ribonucleoprotein Prp3" [UniProtKB:O43395] synonym: "hPrp3" EXACT [UniProtKB:O43395] synonym: "Pre-mRNA-splicing factor 3" EXACT [UniProtKB:O43395] synonym: "U4/U6 snRNP 90 kDa protein" EXACT [UniProtKB:O43395] xref: EMBL:AAC09069.1 xref: EMBL:AAC51926.1 xref: EMBL:AAH00184.1 xref: EMBL:AAH01954.1 xref: EMBL:CAH70312.1 xref: EMBL:EAW53556.1 xref: UniProtKB:O43395 xref: UniProtKB:O43446 xref: UniProtKB:Q5VT54 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022532 ! PRPF3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015490 ! dvl2-prpf3 physical interaction relationship: transforms_into CCO:B0069556 ! PRPF3_HUMAN-Phosphoserine133 relationship: transforms_into CCO:B0069557 ! PRPF3_HUMAN-Phosphoserine356 relationship: transforms_into CCO:B0069558 ! PRPF3_HUMAN-Phosphoserine619 [Term] id: CCO:B0062913 name: GNPI1_HUMAN def: "Glucosamine-6-phosphate isomerase 1" [UniProtKB:P46926] synonym: "EC 3.5.99.6" EXACT [UniProtKB:P46926] synonym: "GlcN6P deaminase 1" EXACT [UniProtKB:P46926] synonym: "Glucosamine-6-phosphate deaminase 1" EXACT [UniProtKB:P46926] synonym: "GNPDA 1" EXACT [UniProtKB:P46926] synonym: "Oscillin" EXACT [UniProtKB:P46926] xref: EMBL:AAB84217.1 xref: EMBL:AAB88748.1 xref: EMBL:AAC05123.1 xref: EMBL:AAC62119.1 xref: EMBL:AAH12853.1 xref: EMBL:AAH20769.1 xref: EMBL:AAH22322.1 xref: EMBL:BAA06544.2 xref: EMBL:CAA05259.1 xref: UniProtKB:P46926 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022283 ! GNPDA1_human relationship: has_function CCO:F0000761 ! glucosamine-6-phosphate deaminase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015492 ! ewsr1-gnpda1 physical interaction [Term] id: CCO:B0062914 name: Q96HL7_HUMAN def: "EPB41L3 protein" [UniProtKB:Q96HL7] xref: EMBL:AAH08377.2 xref: UniProtKB:Q96HL7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022204 ! EPB41L3_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0015495 ! mbip-q96hl7 physical interaction [Term] id: CCO:B0062915 name: NCALD_HUMAN def: "Neurocalcin-delta" [UniProtKB:P61601] xref: EMBL:AAH36098.1 xref: EMBL:AAH63428.1 xref: EMBL:AAK34951.1 xref: EMBL:CAB66547.1 xref: UniProtKB:P29554 xref: UniProtKB:P61601 xref: UniProtKB:Q8IYC3 xref: UniProtKB:Q9H0W2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022428 ! NCALD_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0002987 ! tubulin binding relationship: has_function CCO:F0004372 ! clathrin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000975 ! clathrin coat of trans-Golgi network vesicle relationship: participates_in CCO:I0015508 ! dtx2-ncald physical interaction [Term] id: CCO:B0062916 name: STAM2_HUMAN def: "Signal transducing adapter molecule 2" [UniProtKB:O75886] synonym: "Hrs-binding protein" EXACT [UniProtKB:O75886] synonym: "STAM-2" EXACT [UniProtKB:O75886] xref: EMBL:AAC63963.1 xref: EMBL:AAC63964.1 xref: EMBL:AAH28740.1 xref: EMBL:AAY14712.1 xref: EMBL:CAB63735.1 xref: UniProtKB:O75886 xref: UniProtKB:Q7LDQ0 xref: UniProtKB:Q9UF58 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022680 ! STAM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015513 ! l3mbtl2-stam2 physical interaction relationship: participates_in CCO:I0015651 ! hgs-stam2 physical interaction relationship: participates_in CCO:I0015829 ! stam2-stambp physical interaction relationship: transforms_into CCO:B0070960 ! STAM2_HUMAN-Phosphotyrosine192 relationship: transforms_into CCO:B0070961 ! STAM2_HUMAN-Phosphotyrosine371 relationship: transforms_into CCO:B0070962 ! STAM2_HUMAN-Phosphotyrosine374 [Term] id: CCO:B0062917 name: SNAA_HUMAN def: "Alpha-soluble NSF attachment protein" [UniProtKB:P54920] synonym: "N-ethylmaleimide-sensitive factor attachment protein alpha" EXACT [UniProtKB:P54920] synonym: "SNAP-alpha" EXACT [UniProtKB:P54920] xref: EMBL:AAC80170.1 xref: EMBL:AAH01165.1 xref: EMBL:AAH07432.1 xref: EMBL:AAH28234.1 xref: EMBL:AAH91511.1 xref: EMBL:AAV38375.1 xref: UniProtKB:P54920 xref: UniProtKB:Q96IK3 xref: UniProtKB:Q9BVJ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022659 ! NAPA_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015514 ! napa-rtn4 physical interaction [Term] id: CCO:B0062918 name: ELAV3_HUMAN def: "ELAV-like protein 3" [UniProtKB:Q14576] synonym: "Hu-antigen C" EXACT [UniProtKB:Q14576] synonym: "HuC" EXACT [UniProtKB:Q14576] synonym: "Paraneoplastic cerebellar degeneration-associated antigen" EXACT [UniProtKB:Q14576] synonym: "Paraneoplastic limbic encephalitis antigen 21" EXACT [UniProtKB:Q14576] xref: EMBL:AAA58677.1 xref: EMBL:AAH14144.1 xref: EMBL:AAK67714.1 xref: EMBL:BAA21838.1 xref: UniProtKB:Q14576 xref: UniProtKB:Q16135 xref: UniProtKB:Q96CL8 xref: UniProtKB:Q96QS9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022216 ! ELAVL3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015517 ! elavl3-ewsr1 physical interaction [Term] id: CCO:B0062919 name: NRBP_HUMAN def: "Nuclear receptor-binding protein" [UniProtKB:Q9UHY1] xref: EMBL:AAF21967.1 xref: EMBL:AAH01221.1 xref: EMBL:AAY14847.1 xref: EMBL:BAA91993.1 xref: EMBL:BAB55185.1 xref: EMBL:BAD96856.1 xref: EMBL:CAB66617.1 xref: UniProtKB:Q53FZ5 xref: UniProtKB:Q96SU3 xref: UniProtKB:Q9UHY1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022457 ! NRBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015519 ! bcon3-tsc22d4 physical interaction relationship: participates_in CCO:I0015963 ! nrbp-rac3-2 physical interaction relationship: participates_in CCO:I0019283 ! nrbp-rac3-3 physical interaction relationship: participates_in CCO:I0019506 ! nrbp-rac3-1 physical interaction relationship: transforms_into CCO:B0068826 ! NRBP_HUMAN-Phosphothreonine431 relationship: transforms_into CCO:B0068827 ! NRBP_HUMAN-Phosphothreonine433 relationship: transforms_into CCO:B0068828 ! NRBP_HUMAN-Phosphothreonine441 [Term] id: CCO:B0062920 name: Q96FY4_HUMAN def: "Sorbin and SH3 domain containing 3" [UniProtKB:Q96FY4] xref: EMBL:AAH10146.1 xref: UniProtKB:Q96FY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0020449 ! SORBS3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015521 ! scam_1-zbtb25 physical interaction relationship: participates_in CCO:I0015560 ! efs-scam_1 physical interaction relationship: participates_in CCO:I0015676 ! dvl2-scam_1 physical interaction relationship: participates_in CCO:I0015758 ! hnrpk-scam_1 physical interaction [Term] id: CCO:B0062921 name: Q8IYD4_HUMAN def: "ELAVL4 protein" [UniProtKB:Q8IYD4] xref: EMBL:AAH36071.1 xref: UniProtKB:Q8IYD4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022844 ! ELAVL4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015524 ! elavl4-ewsr1 physical interaction [Term] id: CCO:B0062922 name: CF165_HUMAN def: "Uncharacterized protein C6orf165" [UniProtKB:Q8IYR0] xref: EMBL:AAH35083.2 xref: EMBL:BAC04234.1 xref: EMBL:CAD92567.1 xref: UniProtKB:Q8IYR0 xref: UniProtKB:Q8N9U4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022116 ! C6orf165_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015532 ! c6orf165-mdfi physical interaction [Term] id: CCO:B0062923 name: ATG12_HUMAN def: "Autophagy-related protein 12" [UniProtKB:O94817] synonym: "APG12-like" EXACT [UniProtKB:O94817] xref: EMBL:AAH11033.1 xref: EMBL:AAH12266.2 xref: EMBL:BAA36493.1 xref: UniProtKB:O94817 xref: UniProtKB:Q6PJV2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022058 ! ATG12_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015537 ! apg12l-mdfi physical interaction [Term] id: CCO:B0062924 name: DPCD_HUMAN def: "Protein DPCD" [UniProtKB:Q9BVM2] xref: EMBL:AAH01082.2 xref: EMBL:AAH31695.1 xref: EMBL:AAS46252.1 xref: EMBL:BAF82843.1 xref: EMBL:CAB53691.2 xref: EMBL:CAI41040.1 xref: UniProtKB:A8K289 xref: UniProtKB:Q6QNL3 xref: UniProtKB:Q8N5R1 xref: UniProtKB:Q9BVM2 xref: UniProtKB:Q9UFY6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022194 ! DPCD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015545 ! dpcd-ruvbl2 physical interaction [Term] id: CCO:B0062925 name: HDDC3_HUMAN def: "HD domain-containing protein 3" [UniProtKB:Q8N4P3] xref: EMBL:AAH33794.1 xref: UniProtKB:Q8N4P3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022303 ! HDDC3_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015546 ! hddc3-nmi physical interaction [Term] id: CCO:B0062926 name: PRR13_HUMAN def: "Proline-rich protein 13" [UniProtKB:Q9NZ81] xref: EMBL:AAF67628.1 xref: EMBL:AAH14257.1 xref: EMBL:AAH16064.1 xref: EMBL:AAH66943.1 xref: EMBL:CAE45980.1 xref: EMBL:CAG38490.1 xref: UniProtKB:Q6FIG7 xref: UniProtKB:Q6MZP8 xref: UniProtKB:Q6NXQ6 xref: UniProtKB:Q6PKF9 xref: UniProtKB:Q9NZ81 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022534 ! PRR13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015549 ! dkfzp564j157-sdcbp2 physical interaction [Term] id: CCO:B0062927 name: Q9Y260_HUMAN def: "DNA-binding protein ABP/ZF (Transient receptor potential cation channel, subfamily V, member 6, isoform CRA_a) (ABP/ZF) (TRPV6 protein)" [UniProtKB:Q9Y260] xref: EMBL:AAB40152.1 xref: EMBL:AAH34814.1 xref: EMBL:CAA58757.1 xref: EMBL:EAW51897.1 xref: UniProtKB:Q9Y260 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022866 ! TRPV6_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015550 ! mdfi-zfab physical interaction [Term] id: CCO:B0062928 name: PVRL2_HUMAN def: "Poliovirus receptor-related protein 2 precursor" [UniProtKB:Q92692] synonym: "CD112 antigen" EXACT [UniProtKB:Q92692] synonym: "Herpes virus entry mediator B" EXACT [UniProtKB:Q92692] synonym: "HveB" EXACT [UniProtKB:Q92692] synonym: "Nectin-2" EXACT [UniProtKB:Q92692] xref: EMBL:AAC23797.1 xref: EMBL:AAC82348.1 xref: EMBL:AAD02503.1 xref: EMBL:AAH03091.1 xref: EMBL:CAA56342.1 xref: UniProtKB:O75455 xref: UniProtKB:Q92692 xref: UniProtKB:Q96J29 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022545 ! PVRL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015553 ! mdfi-pvrl2 physical interaction relationship: transforms_into CCO:B0069640 ! PVRL2_HUMAN-Phosphoserine433 [Term] id: CCO:B0062929 name: MALL_HUMAN def: "MAL-like protein" [UniProtKB:Q13021] synonym: "Protein BENE" EXACT [UniProtKB:Q13021] xref: EMBL:AAA76738.1 xref: EMBL:AAH03179.1 xref: UniProtKB:Q13021 xref: UniProtKB:Q9BTU0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022388 ! MALL_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000981 ! clathrin-coated vesicle relationship: located_in CCO:C0002123 ! membrane raft relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:I0015556 ! bene-creb3 physical interaction [Term] id: CCO:B0062930 name: RT18B_HUMAN def: "28S ribosomal protein S18b, mitochondrial precursor" [UniProtKB:Q9Y676] synonym: "MRP-S18-2" EXACT [UniProtKB:Q9Y676] synonym: "MRP-S18-b" EXACT [UniProtKB:Q9Y676] synonym: "Mrps18b" EXACT [UniProtKB:Q9Y676] xref: EMBL:AAD43025.1 xref: EMBL:AAF36103.1 xref: EMBL:AAH05373.1 xref: EMBL:BAD13699.1 xref: EMBL:BAD13700.1 xref: EMBL:BAE78614.1 xref: EMBL:CAH56415.1 xref: EMBL:CAI17765.1 xref: EMBL:CAI17840.1 xref: EMBL:CAI18162.2 xref: EMBL:CAI18569.1 xref: EMBL:CAI41878.1 xref: EMBL:CAM25911.1 xref: EMBL:CAP58452.1 xref: EMBL:EAX03304.1 xref: UniProtKB:A6NDQ0 xref: UniProtKB:Q659G4 xref: UniProtKB:Q9BS27 xref: UniProtKB:Q9Y676 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022618 ! MRPS18B_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000346 ! mitochondrial small ribosomal subunit relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0015557 ! ewsr1-mrps18b physical interaction [Term] id: CCO:B0062931 name: FUZZY_HUMAN def: "Protein fuzzy homolog" [UniProtKB:Q9BT04] xref: EMBL:AAH04445.1 xref: EMBL:AAH10092.1 xref: EMBL:AAH16793.1 xref: EMBL:BAB15454.1 xref: EMBL:EAW52538.1 xref: UniProtKB:Q6PJY0 xref: UniProtKB:Q9BT04 xref: UniProtKB:Q9H613 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022264 ! FUZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0015583 ! c1orf89-flj22688 physical interaction [Term] id: CCO:B0062932 name: GLRX3_HUMAN def: "Glutaredoxin-3" [UniProtKB:O76003] synonym: "PKC-interacting cousin of thioredoxin" EXACT [UniProtKB:O76003] synonym: "PKC-theta-interacting protein" EXACT [UniProtKB:O76003] synonym: "PKCq-interacting protein" EXACT [UniProtKB:O76003] synonym: "Thioredoxin-like protein 2" EXACT [UniProtKB:O76003] xref: EMBL:AAF28841.1 xref: EMBL:AAF28844.1 xref: EMBL:AAH05289.1 xref: EMBL:AAH14372.2 xref: EMBL:CAA09375.1 xref: EMBL:CAC40691.1 xref: EMBL:EAW49152.1 xref: UniProtKB:O76003 xref: UniProtKB:Q5JV01 xref: UniProtKB:Q96CE0 xref: UniProtKB:Q9P1B0 xref: UniProtKB:Q9P1B1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022278 ! GLRX3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015605 ! ciapin1-txnl2 physical interaction relationship: participates_in CCO:I0018137 ! prkcq-txnl2-3 physical interaction relationship: participates_in CCO:I0018138 ! prkcq-txnl2-4 colocalization relationship: participates_in CCO:I0018175 ! prkcq-txnl2-5 physical interaction relationship: participates_in CCO:I0018588 ! prkcq-txnl2-2 physical interaction relationship: participates_in CCO:I0019225 ! prkcq-txnl2-1 physical interaction relationship: transforms_into CCO:B0066470 ! GLRX3_HUMAN-N-acetylalanine2 [Term] id: CCO:B0062933 name: TSN3_HUMAN def: "Tetraspanin-3" [UniProtKB:O60637] synonym: "Tetraspanin TM4-A" EXACT [UniProtKB:O60637] synonym: "Transmembrane 4 superfamily member 8" EXACT [UniProtKB:O60637] synonym: "Tspan-3" EXACT [UniProtKB:O60637] xref: EMBL:AAC69716.1 xref: EMBL:AAF08362.1 xref: EMBL:AAH00704.1 xref: EMBL:AAH04280.1 xref: EMBL:AAH09248.1 xref: EMBL:AAH11206.1 xref: EMBL:BAA91613.1 xref: EMBL:BAA91615.1 xref: EMBL:BAA91627.1 xref: UniProtKB:O60637 xref: UniProtKB:Q9BW22 xref: UniProtKB:Q9NVX9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022743 ! TSPAN3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015609 ! ewsr1-tspan3 physical interaction [Term] id: CCO:B0062934 name: HAX1_HUMAN def: "HCLS1-associated protein X-1" [UniProtKB:O00165] synonym: "HAX-1" EXACT [UniProtKB:O00165] synonym: "HS1-associating protein X-1" EXACT [UniProtKB:O00165] synonym: "HS1-binding protein 1" EXACT [UniProtKB:O00165] xref: EMBL:AAB51196.1 xref: EMBL:AAH05240.1 xref: EMBL:AAH14314.1 xref: EMBL:AAH15209.1 xref: EMBL:AAH16730.1 xref: EMBL:BAF83315.1 xref: EMBL:CAH70481.1 xref: EMBL:EAW53212.1 xref: UniProtKB:O00165 xref: UniProtKB:Q5VYD5 xref: UniProtKB:Q96AU4 xref: UniProtKB:Q9BS80 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022300 ! HAX1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0015611 ! eif3s5-hs1bp1 physical interaction relationship: participates_in CCO:I0016684 ! map3k3-hs1bp1 physical interaction relationship: participates_in CCO:I0016994 ! tnfrsf1a-hs1bp1 physical interaction relationship: participates_in CCO:I0020289 ! dgkd-hs1bp1 physical interaction relationship: transforms_into CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 [Term] id: CCO:B0062935 name: SF3B4_HUMAN def: "Splicing factor 3B subunit 4" [UniProtKB:Q15427] synonym: "Pre-mRNA-splicing factor SF3b 49 kDa subunit" EXACT [UniProtKB:Q15427] synonym: "SAP 49" EXACT [UniProtKB:Q15427] synonym: "SF3b50" EXACT [UniProtKB:Q15427] synonym: "Spliceosome-associated protein 49" EXACT [UniProtKB:Q15427] xref: EMBL:AAA60300.1 xref: EMBL:AAH04273.1 xref: EMBL:AAH13886.1 xref: UniProtKB:Q15427 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022644 ! SF3B4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015612 ! nck2-sf3b4 physical interaction relationship: transforms_into CCO:B0070395 ! SF3B4_HUMAN-Phosphotyrosine16 relationship: transforms_into CCO:B0070396 ! SF3B4_HUMAN-Phosphotyrosine56 [Term] id: CCO:B0062936 name: RWDD1_HUMAN def: "RWD domain-containing protein 1" [UniProtKB:Q9H446] synonym: "DRG family-regulatory protein 2" EXACT [UniProtKB:Q9H446] xref: EMBL:AAD27733.1 xref: EMBL:AAD40376.1 xref: EMBL:AAH15802.1 xref: EMBL:CAC14427.1 xref: UniProtKB:Q9H446 xref: UniProtKB:Q9Y313 xref: UniProtKB:Q9Y6B3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022622 ! RWDD1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015615 ! drg2-rwdd1 physical interaction [Term] id: CCO:B0062937 name: CCD91_HUMAN def: "Coiled-coil domain-containing protein 91" [UniProtKB:Q7Z6B0] synonym: "GGA-binding partner" EXACT [UniProtKB:Q7Z6B0] synonym: "p56 accessory protein" EXACT [UniProtKB:Q7Z6B0] xref: EMBL:AAH28682.1 xref: EMBL:AAP20065.1 xref: EMBL:AAP42284.1 xref: EMBL:BAA91995.1 xref: EMBL:CAG33558.1 xref: EMBL:CAH18385.1 xref: UniProtKB:Q68D43 xref: UniProtKB:Q6IA78 xref: UniProtKB:Q7Z6B0 xref: UniProtKB:Q8NEN7 xref: UniProtKB:Q9NUW9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022103 ! CCDC91_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0015618 ! ewsr1-ggabp physical interaction [Term] id: CCO:B0062938 name: YA004_HUMAN def: "Putative coiled-coil domain-containing protein MGC12538" [UniProtKB:Q96IX9] xref: EMBL:AAH07072.1 xref: EMBL:CAI22641.1 xref: UniProtKB:Q96IX9 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015625 ! mgc12538-traf2 physical interaction [Term] id: CCO:B0062939 name: F105B_HUMAN def: "Protein FAM105B" [UniProtKB:Q96BN8] xref: EMBL:AAH07706.3 xref: EMBL:AAH15392.2 xref: EMBL:BAC03828.1 xref: UniProtKB:Q8NAS0 xref: UniProtKB:Q96BN8 xref: UniProtKB:Q96IA3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022235 ! FAM105B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015635 ! dvl2-loc90268 physical interaction [Term] id: CCO:B0062940 name: LERL1_HUMAN def: "Leptin receptor overlapping transcript-like 1" [UniProtKB:O95214] xref: EMBL:AAC98697.1 xref: EMBL:AAH00642.1 xref: EMBL:AAQ89037.1 xref: UniProtKB:O95214 xref: UniProtKB:Q9BW48 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022368 ! LEPROTL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015644 ! klrg1-leprotl1 physical interaction [Term] id: CCO:B0062941 name: NTNG2_HUMAN def: "Netrin-G2 precursor" [UniProtKB:Q96CW9] synonym: "Laminet-2" EXACT [UniProtKB:Q96CW9] xref: EMBL:AAH13770.1 xref: EMBL:AAQ88532.1 xref: EMBL:BAB47486.2 xref: UniProtKB:Q6UXY0 xref: UniProtKB:Q96CW9 xref: UniProtKB:Q96JH0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022460 ! NTNG2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001959 ! anchored to plasma membrane relationship: participates_in CCO:I0015645 ! ewsr1-ntng2 physical interaction [Term] id: CCO:B0062942 name: CSR2B_HUMAN def: "Cysteine-rich protein 2-binding protein" [UniProtKB:Q9H8E8] synonym: "CRP2-binding partner" EXACT [UniProtKB:Q9H8E8] synonym: "CRP2BP" EXACT [UniProtKB:Q9H8E8] synonym: "CSRP2-binding protein" EXACT [UniProtKB:Q9H8E8] xref: EMBL:AAG10249.1 xref: EMBL:AAH07537.1 xref: EMBL:BAB14669.1 xref: EMBL:CAB56651.2 xref: UniProtKB:Q96GW6 xref: UniProtKB:Q96IH3 xref: UniProtKB:Q9H8E8 xref: UniProtKB:Q9HBF0 xref: UniProtKB:Q9UIY5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022157 ! CSRP2BP_human relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0004370 ! LIM domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015658 ! csrp2bp-mbip physical interaction [Term] id: CCO:B0062943 name: LASP1_HUMAN def: "LIM and SH3 domain protein 1" [UniProtKB:Q14847] synonym: "LASP-1" EXACT [UniProtKB:Q14847] synonym: "MLN 50" EXACT [UniProtKB:Q14847] xref: EMBL:AAH07560.1 xref: EMBL:AAH12460.1 xref: EMBL:CAA57833.1 xref: UniProtKB:Q14847 xref: UniProtKB:Q96ED2 xref: UniProtKB:Q96IG0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022361 ! LASP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015659 ! lasp1-mdfi physical interaction relationship: transforms_into CCO:B0067572 ! LASP1_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0067573 ! LASP1_HUMAN-Phosphothreonine68 relationship: transforms_into CCO:B0067574 ! LASP1_HUMAN-Phosphothreonine104 relationship: transforms_into CCO:B0067575 ! LASP1_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0067576 ! LASP1_HUMAN-Phosphoserine151 relationship: transforms_into CCO:B0067577 ! LASP1_HUMAN-Phosphotyrosine171 [Term] id: CCO:B0062944 name: Q96IH6_HUMAN def: "EMILIN1 protein" [UniProtKB:Q96IH6] xref: EMBL:AAH07530.1 xref: UniProtKB:Q96IH6 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0015661 ! nmi-q96ih6 physical interaction [Term] id: CCO:B0062945 name: UBL7_HUMAN def: "Ubiquitin-like protein 7" [UniProtKB:Q96S82] synonym: "BMSC-UbP" EXACT [UniProtKB:Q96S82] synonym: "Bone marrow stromal cell ubiquitin-like protein" EXACT [UniProtKB:Q96S82] synonym: "Ubiquitin-like protein SB132" EXACT [UniProtKB:Q96S82] xref: EMBL:AAH07913.1 xref: EMBL:AAH30055.1 xref: EMBL:AAH33919.1 xref: EMBL:AAK67643.1 xref: UniProtKB:Q96I03 xref: UniProtKB:Q96S82 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022757 ! UBL7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015671 ! ercc1-sb132 physical interaction relationship: transforms_into CCO:B0071671 ! UBL7_HUMAN-Phosphoserine230 [Term] id: CCO:B0062946 name: THEG_HUMAN def: "Testicular haploid expressed gene protein" [UniProtKB:Q9P2T0] synonym: "Cancer/testis antigen 56" EXACT [UniProtKB:Q9P2T0] synonym: "CT56" EXACT [UniProtKB:Q9P2T0] xref: EMBL:AAG17663.1 xref: EMBL:AAH28574.1 xref: EMBL:BAA93718.1 xref: EMBL:EAW61204.1 xref: UniProtKB:A6NMJ8 xref: UniProtKB:Q9P2T0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022711 ! THEG_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0015675 ! mdfi-theg physical interaction [Term] id: CCO:B0062947 name: SFR16_HUMAN def: "Splicing factor, arginine/serine-rich 16" [UniProtKB:Q8N2M8] synonym: "Suppressor of white-apricot homolog 2" EXACT [UniProtKB:Q8N2M8] xref: EMBL:AAC82339.1 xref: EMBL:AAC82340.1 xref: EMBL:AAH13178.1 xref: EMBL:AAH80554.1 xref: EMBL:AAQ89303.1 xref: EMBL:BAC11078.1 xref: UniProtKB:O96026 xref: UniProtKB:Q6UW71 xref: UniProtKB:Q8N2M8 xref: UniProtKB:Q96DX2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022646 ! SFRS16_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015681 ! pepp2-sfrs16 physical interaction relationship: participates_in CCO:I0017565 ! sfrs16-atxn1 physical interaction relationship: transforms_into CCO:B0070403 ! SFR16_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0070404 ! SFR16_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0070405 ! SFR16_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0070406 ! SFR16_HUMAN-Phosphothreonine304 relationship: transforms_into CCO:B0070407 ! SFR16_HUMAN-Phosphoserine316 relationship: transforms_into CCO:B0070408 ! SFR16_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0070409 ! SFR16_HUMAN-Phosphoserine516 relationship: transforms_into CCO:B0070410 ! SFR16_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0070411 ! SFR16_HUMAN-Phosphoserine520 relationship: transforms_into CCO:B0070412 ! SFR16_HUMAN-Phosphoserine532 [Term] id: CCO:B0062948 name: CHAC1_HUMAN def: "Cation transport regulator-like protein 1" [UniProtKB:Q9BUX1] xref: EMBL:AAH01683.1 xref: EMBL:AAH01847.1 xref: EMBL:AAH19625.1 xref: UniProtKB:Q9BUX1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022121 ! CHAC1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0015686 ! mgc4504-pepp2 physical interaction relationship: participates_in CCO:I0019425 ! mgc4504-pepp2-1 physical interaction [Term] id: CCO:B0062949 name: XTP3A_HUMAN def: "XTP3-transactivated gene A protein" [UniProtKB:Q9H773] synonym: "RS21C6" EXACT [UniProtKB:Q9H773] xref: EMBL:AAH01344.1 xref: EMBL:AAK14927.1 xref: EMBL:AAK48422.1 xref: EMBL:AAR26724.1 xref: EMBL:BAB15025.1 xref: EMBL:CAG33616.1 xref: UniProtKB:Q9H773 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022790 ! XTP3TPA_human relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015687 ! nif3l1-xtp3tpa physical interaction relationship: transforms_into CCO:B0071898 ! XTP3A_HUMAN-Phosphoserine138 [Term] id: CCO:B0062950 name: Q8N4C1_HUMAN def: "TRPV5 protein" [UniProtKB:Q8N4C1] xref: EMBL:AAH34740.1 xref: UniProtKB:Q8N4C1 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015698 ! ewsr1-q8n4c1 physical interaction [Term] id: CCO:B0062951 name: Q96F93_HUMAN def: "ZNF101 protein" [UniProtKB:Q96F93] xref: EMBL:AAH11502.2 xref: UniProtKB:Q96F93 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0020616 ! ZNF101_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015699 ! mdfi-znf101 physical interaction [Term] id: CCO:B0062952 name: Q9BPY1_HUMAN def: "C1orf116 protein" [UniProtKB:Q9BPY1] xref: EMBL:AAH01943.1 xref: UniProtKB:Q9BPY1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022856 ! C1orf116_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015701 ! c1orf116-homer1 physical interaction [Term] id: CCO:B0062953 name: KIME_HUMAN def: "Mevalonate kinase" [UniProtKB:Q03426] synonym: "EC 2.7.1.36" EXACT [UniProtKB:Q03426] synonym: "MK" EXACT [UniProtKB:Q03426] xref: EMBL:AAB59362.1 xref: EMBL:AAF82407.1 xref: EMBL:AAH16140.1 xref: EMBL:CAA53059.1 xref: EMBL:CAA53060.1 xref: UniProtKB:Q03426 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022352 ! MVK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000893 ! mevalonate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000359 ! peroxisome relationship: participates_in CCO:I0015708 ! ewsr1-mvk physical interaction [Term] id: CCO:B0062954 name: DNPEP_HUMAN def: "Aspartyl aminopeptidase" [UniProtKB:Q9ULA0] synonym: "EC 3.4.11.21" EXACT [UniProtKB:Q9ULA0] xref: EMBL:AAD01211.2 xref: EMBL:AAH00653.2 xref: EMBL:BAA92014.1 xref: UniProtKB:Q9BW44 xref: UniProtKB:Q9NUV5 xref: UniProtKB:Q9ULA0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022192 ! DNPEP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015713 ! dnpep-mdfi physical interaction [Term] id: CCO:B0062955 name: HNRPM_HUMAN def: "Heterogeneous nuclear ribonucleoprotein M" [UniProtKB:P52272] synonym: "hnRNP M" EXACT [UniProtKB:P52272] xref: EMBL:AAA36192.1 xref: EMBL:AAC16002.1 xref: EMBL:AAH00138.2 xref: EMBL:AAH08895.2 xref: EMBL:AAH19580.1 xref: EMBL:AAL31359.1 xref: UniProtKB:P52272 xref: UniProtKB:Q15584 xref: UniProtKB:Q8WZ44 xref: UniProtKB:Q96H56 xref: UniProtKB:Q9BWL9 xref: UniProtKB:Q9Y492 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022310 ! HNRNPM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015730 ! hnrpm-lmo3 physical interaction relationship: transforms_into CCO:B0066868 ! HNRPM_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0066869 ! HNRPM_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0066870 ! HNRPM_HUMAN-Phosphoserine468 relationship: transforms_into CCO:B0066871 ! HNRPM_HUMAN-Phosphoserine513 relationship: transforms_into CCO:B0066872 ! HNRPM_HUMAN-Phosphoserine528 relationship: transforms_into CCO:B0066873 ! HNRPM_HUMAN-Phosphoserine588 relationship: transforms_into CCO:B0066874 ! HNRPM_HUMAN-Phosphoserine618 relationship: transforms_into CCO:B0066875 ! HNRPM_HUMAN-Phosphoserine633 relationship: transforms_into CCO:B0066876 ! HNRPM_HUMAN-Phosphoserine637 relationship: transforms_into CCO:B0066877 ! HNRPM_HUMAN-Phosphoserine701 [Term] id: CCO:B0062956 name: ODPX_HUMAN def: "Pyruvate dehydrogenase protein X component, mitochondrial precursor" [UniProtKB:O00330] synonym: "Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex" EXACT [UniProtKB:O00330] synonym: "E3-binding protein" EXACT [UniProtKB:O00330] synonym: "E3BP" EXACT [UniProtKB:O00330] synonym: "Lipoyl-containing pyruvate dehydrogenase complex component X" EXACT [UniProtKB:O00330] synonym: "proX" EXACT [UniProtKB:O00330] xref: EMBL:AAB50223.1 xref: EMBL:AAB66315.1 xref: EMBL:AAC39661.1 xref: EMBL:AAH10389.1 xref: EMBL:CAA73606.1 xref: EMBL:CAC18649.1 xref: UniProtKB:O00330 xref: UniProtKB:O60221 xref: UniProtKB:Q96FV8 xref: UniProtKB:Q99783 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022475 ! PDHX_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0004659 ! lipoic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0015742 ! ewsr1-pdhx physical interaction [Term] id: CCO:B0062957 name: PHLA1_HUMAN def: "Pleckstrin homology-like domain family A member 1" [UniProtKB:Q8WV24] synonym: "Apoptosis-associated nuclear protein" EXACT [UniProtKB:Q8WV24] synonym: "PQ-rich protein" EXACT [UniProtKB:Q8WV24] synonym: "Proline- and glutamine-rich protein" EXACT [UniProtKB:Q8WV24] synonym: "Proline- and histidine-rich protein" EXACT [UniProtKB:Q8WV24] synonym: "T-cell death-associated gene 51 protein" EXACT [UniProtKB:Q8WV24] xref: EMBL:AAF36387.1 xref: EMBL:AAF64165.1 xref: EMBL:AAH18929.3 xref: EMBL:AAI10821.1 xref: EMBL:CAA90576.1 xref: UniProtKB:Q15184 xref: UniProtKB:Q2TAN2 xref: UniProtKB:Q8WV24 xref: UniProtKB:Q9NZ17 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022511 ! PHLDA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0015743 ! mdfi-phlda1 physical interaction relationship: participates_in CCO:I0018523 ! phlda1-eif3s7-2 physical interaction relationship: participates_in CCO:I0019279 ! phlda1-eif3s7-1 physical interaction [Term] id: CCO:B0062958 name: CJ012_HUMAN def: "Uncharacterized protein C10orf12" [UniProtKB:Q8N655] xref: EMBL:AAH24315.1 xref: EMBL:BAB14396.1 xref: EMBL:CAB43214.1 xref: EMBL:CAH70916.1 xref: UniProtKB:Q8N655 xref: UniProtKB:Q9H945 xref: UniProtKB:Q9Y457 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022126 ! C10orf12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015744 ! c10orf12-ewsr1 physical interaction relationship: transforms_into CCO:B0065871 ! CJ012_HUMAN-Phosphoserine273 relationship: transforms_into CCO:B0065872 ! CJ012_HUMAN-Phosphothreonine428 relationship: transforms_into CCO:B0065873 ! CJ012_HUMAN-Phosphothreonine993 relationship: transforms_into CCO:B0065874 ! CJ012_HUMAN-Phosphoserine996 [Term] id: CCO:B0062959 name: CH048_HUMAN def: "Uncharacterized protein C8orf48" [UniProtKB:Q96LL4] xref: EMBL:AAH31245.1 xref: EMBL:AAQ02889.1 xref: EMBL:BAB71677.1 xref: EMBL:BAB71692.1 xref: UniProtKB:Q96LJ9 xref: UniProtKB:Q96LL4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022119 ! C8orf48_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015747 ! c8orf48-mdfi physical interaction [Term] id: CCO:B0062960 name: DCTD_HUMAN def: "Deoxycytidylate deaminase" [UniProtKB:P32321] synonym: "dCMP deaminase" EXACT [UniProtKB:P32321] synonym: "EC 3.5.4.12" EXACT [UniProtKB:P32321] xref: EMBL:AAA35755.1 xref: EMBL:AAC37579.1 xref: EMBL:AAH01286.1 xref: UniProtKB:P32321 xref: UniProtKB:Q9BVD8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022172 ! DCTD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015780 ! dctd-nif3l1 physical interaction relationship: transforms_into CCO:B0065925 ! DCTD_HUMAN-Phosphotyrosine79 [Term] id: CCO:B0062961 name: MTHFS_HUMAN def: "5-formyltetrahydrofolate cyclo-ligase" [UniProtKB:P49914] synonym: "5,10-methenyl-tetrahydrofolate synthetase" EXACT [UniProtKB:P49914] synonym: "EC 6.3.3.2" EXACT [UniProtKB:P49914] synonym: "Methenyl-THF synthetase" EXACT [UniProtKB:P49914] synonym: "MTHFS" EXACT [UniProtKB:P49914] xref: EMBL:AAC41945.1 xref: EMBL:AAH19921.1 xref: UniProtKB:P49914 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022410 ! MTHFS_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001665 ! folic acid binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004368 ! 5-formyltetrahydrofolate cyclo-ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015781 ! mthfs-tsc22d4 physical interaction relationship: transforms_into CCO:B0068318 ! MTHFS_HUMAN-N-acetylalanine2 [Term] id: CCO:B0062962 name: KCMB1_HUMAN def: "Calcium-activated potassium channel subunit beta-1" [UniProtKB:Q16558] synonym: "BK channel subunit beta-1" EXACT [UniProtKB:Q16558] synonym: "BKbeta" EXACT [UniProtKB:Q16558] synonym: "BKbeta1" EXACT [UniProtKB:Q16558] synonym: "Calcium-activated potassium channel subunit beta" EXACT [UniProtKB:Q16558] synonym: "Calcium-activated potassium channel, subfamily M subunit beta-1" EXACT [UniProtKB:Q16558] synonym: "Charybdotoxin receptor subunit beta-1" EXACT [UniProtKB:Q16558] synonym: "Hbeta1" EXACT [UniProtKB:Q16558] synonym: "K(VCA)beta-1" EXACT [UniProtKB:Q16558] synonym: "Maxi K channel subunit beta-1" EXACT [UniProtKB:Q16558] synonym: "Slo-beta" EXACT [UniProtKB:Q16558] synonym: "Slo-beta-1" EXACT [UniProtKB:Q16558] xref: EMBL:AAA81327.1 xref: EMBL:AAB02394.1 xref: EMBL:AAB16825.1 xref: EMBL:AAB16826.1 xref: EMBL:AAB16827.1 xref: EMBL:AAB61396.1 xref: EMBL:AAB61397.1 xref: EMBL:AAB88805.1 xref: EMBL:AAH25707.1 xref: EMBL:AAK95827.1 xref: EMBL:AAS20193.1 xref: EMBL:BAG36693.1 xref: EMBL:EAW61474.1 xref: UniProtKB:O00707 xref: UniProtKB:O00708 xref: UniProtKB:P78475 xref: UniProtKB:Q16558 xref: UniProtKB:Q53YR0 xref: UniProtKB:Q8TAX3 xref: UniProtKB:Q93005 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022350 ! KCNMB1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0002726 ! calcium-activated potassium channel activity relationship: has_function CCO:F0002867 ! potassium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015788 ! ewsr1-kcnmb1 physical interaction [Term] id: CCO:B0062963 name: Q96G05_HUMAN def: "ETNK2 protein" [UniProtKB:Q96G05] synonym: "Ethanolamine kinase 2" EXACT [UniProtKB:Q96G05] synonym: "Ethanolamine kinase 2, isoform CRA_b" EXACT [UniProtKB:Q96G05] xref: EMBL:AAH10082.1 xref: EMBL:CAI16602.1 xref: EMBL:EAW91502.1 xref: UniProtKB:Q96G05 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022853 ! ETNK2_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015793 ! etnk2-nol3 physical interaction [Term] id: CCO:B0062964 name: TEX28_HUMAN def: "Testis-specific protein TEX28" [UniProtKB:O15482] xref: EMBL:AAB71379.1 xref: EMBL:AAH26183.1 xref: EMBL:CAI41959.1 xref: EMBL:CAI43243.1 xref: EMBL:EAW72754.1 xref: UniProtKB:B1B1E8 xref: UniProtKB:O15482 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022707 ! TEX28_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015802 ! cxorf2-eps8 physical interaction [Term] id: CCO:B0062965 name: FA46B_HUMAN def: "Protein FAM46B" [UniProtKB:Q96A09] xref: EMBL:AAH12790.1 xref: EMBL:AAH14160.1 xref: EMBL:CAI13555.1 xref: UniProtKB:Q96A09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022245 ! FAM46B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015806 ! fam46b-pepp2 physical interaction relationship: participates_in CCO:I0017559 ! fam46b-atxn1 physical interaction [Term] id: CCO:B0062966 name: FA71C_HUMAN def: "Protein FAM71C" [UniProtKB:Q8NEG0] xref: EMBL:AAH31221.1 xref: UniProtKB:Q8NEG0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022247 ! FAM71C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015807 ! mgc39520-rab2 physical interaction [Term] id: CCO:B0062967 name: FA96A_HUMAN def: "UPF0195 protein FAM96A" [UniProtKB:Q9H5X1] xref: EMBL:AAH08865.1 xref: EMBL:BAB15496.1 xref: UniProtKB:Q9H5X1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022249 ! FAM96A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015810 ! flj22875-wdr39 physical interaction [Term] id: CCO:B0062968 name: VPS28_HUMAN def: "Vacuolar protein sorting-associated protein 28 homolog" [UniProtKB:Q9UK41] synonym: "H-Vps28" EXACT [UniProtKB:Q9UK41] xref: EMBL:AAF00499.1 xref: EMBL:AAH06485.1 xref: EMBL:AAH19321.1 xref: UniProtKB:Q9UK41 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022777 ! VPS28_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0015848 ! tsg101-vps28-1 physical interaction relationship: participates_in CCO:I0020686 ! vps28-fabp3 physical interaction [Term] id: CCO:B0062969 name: NLTP_HUMAN def: "Non-specific lipid-transfer protein" [UniProtKB:P22307] synonym: "EC 2.3.1.176" EXACT [UniProtKB:P22307] synonym: "NSL-TP" EXACT [UniProtKB:P22307] synonym: "Propanoyl-CoA C-acyltransferase" EXACT [UniProtKB:P22307] synonym: "SCP-2" EXACT [UniProtKB:P22307] synonym: "SCP-chi" EXACT [UniProtKB:P22307] synonym: "SCP-X" EXACT [UniProtKB:P22307] synonym: "SCPX" EXACT [UniProtKB:P22307] synonym: "Sterol carrier protein 2" EXACT [UniProtKB:P22307] synonym: "Sterol carrier protein X" EXACT [UniProtKB:P22307] xref: EMBL:AAA03557.1 xref: EMBL:AAA03558.1 xref: EMBL:AAA03559.1 xref: EMBL:AAB24921.1 xref: EMBL:AAB41286.1 xref: EMBL:AAH05911.1 xref: UniProtKB:P22307 xref: UniProtKB:Q15432 xref: UniProtKB:Q16622 xref: UniProtKB:Q99430 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022447 ! SCP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015863 ! scp2-cav1-3 physical interaction relationship: participates_in CCO:I0015864 ! cav1-scp2-3 physical interaction relationship: transforms_into CCO:B0068741 ! NLTP_HUMAN-N6-acetyllysine142 relationship: transforms_into CCO:B0068742 ! NLTP_HUMAN-N6-acetyllysine173 relationship: transforms_into CCO:B0068743 ! NLTP_HUMAN-Phosphotyrosine197 relationship: transforms_into CCO:B0068744 ! NLTP_HUMAN-Phosphotyrosine204 relationship: transforms_into CCO:B0068745 ! NLTP_HUMAN-N6-acetyllysine282 relationship: transforms_into CCO:B0068746 ! NLTP_HUMAN-N6-acetyllysine341 relationship: transforms_into CCO:B0068747 ! NLTP_HUMAN-Phosphoserine425 relationship: transforms_into CCO:B0068748 ! NLTP_HUMAN-N6-acetyllysine453 [Term] id: CCO:B0062970 name: NIN_HUMAN def: "Ninein" [UniProtKB:Q8N4C6] synonym: "Glycogen synthase kinase 3 beta-interacting protein" EXACT [UniProtKB:Q8N4C6] synonym: "GSK3B-interacting protein" EXACT [UniProtKB:Q8N4C6] synonym: "hNinein" EXACT [UniProtKB:Q8N4C6] xref: EMBL:AAF23015.2 xref: EMBL:AAG17027.1 xref: EMBL:AAG33512.2 xref: EMBL:AAH34708.2 xref: EMBL:AAH65521.1 xref: EMBL:AAK00628.1 xref: EMBL:AAK00629.1 xref: EMBL:AAK00630.1 xref: EMBL:AAK27375.1 xref: EMBL:AAK27376.1 xref: EMBL:AAK27377.1 xref: EMBL:BAB13391.2 xref: EMBL:BAB15640.1 xref: UniProtKB:Q6P0P6 xref: UniProtKB:Q8N4C6 xref: UniProtKB:Q9BWU6 xref: UniProtKB:Q9C012 xref: UniProtKB:Q9C013 xref: UniProtKB:Q9C014 xref: UniProtKB:Q9H5I6 xref: UniProtKB:Q9HAT7 xref: UniProtKB:Q9HBY5 xref: UniProtKB:Q9HCK7 xref: UniProtKB:Q9UH61 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022445 ! NIN_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0015865 ! gsk3b-nin-1 physical interaction relationship: participates_in CCO:I0018720 ! gsk3b-nin-2 phosphorylation relationship: transforms_into CCO:B0068719 ! NIN_HUMAN-Phosphoserine1550 [Term] id: CCO:B0062971 name: ISK7_HUMAN def: "Serine protease inhibitor Kazal-type 7 precursor" [UniProtKB:P58062] synonym: "ECRG-2" EXACT [UniProtKB:P58062] synonym: "Esophagus cancer-related gene 2 protein" EXACT [UniProtKB:P58062] xref: EMBL:AAI09386.1 xref: EMBL:AAI10068.1 xref: EMBL:AAK27795.1 xref: EMBL:AAQ89431.1 xref: UniProtKB:P58062 xref: UniProtKB:Q32LY0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022343 ! SPINK7_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0015880 ! spink7-mt2a-1 direct interaction relationship: participates_in CCO:I0017806 ! mt2a-spink7 physical interaction relationship: participates_in CCO:I0017807 ! spink7-mt2a-2 physical interaction relationship: participates_in CCO:I0018724 ! spink7-mt2a physical interaction relationship: participates_in CCO:I0018725 ! spink7-ebp42 physical interaction relationship: participates_in CCO:I0019480 ! spink7-mt2a-3 colocalization [Term] id: CCO:B0062972 name: LSM2_HUMAN def: "U6 snRNA-associated Sm-like protein LSm2" [UniProtKB:Q9Y333] synonym: "Protein G7b" EXACT [UniProtKB:Q9Y333] synonym: "Small nuclear ribonuclear protein D homolog" EXACT [UniProtKB:Q9Y333] synonym: "snRNP core Sm-like protein Sm-x5" EXACT [UniProtKB:Q9Y333] xref: EMBL:AAD21818.1 xref: EMBL:AAD56226.1 xref: EMBL:AAG33023.1 xref: EMBL:AAG49438.1 xref: EMBL:AAH09192.1 xref: EMBL:BAB63302.1 xref: EMBL:CAB52190.1 xref: UniProtKB:Q9Y333 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022378 ! LSM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015890 ! lsm2-znf408-2 physical interaction relationship: participates_in CCO:I0017320 ! lsm2-znf408-1 physical interaction relationship: participates_in CCO:I0017340 ! znf408-lsm2 physical interaction relationship: participates_in CCO:I0018450 ! lsm2-znf408 physical interaction relationship: transforms_into CCO:B0067786 ! LSM2_HUMAN-Phosphotyrosine35 relationship: transforms_into CCO:B0067787 ! LSM2_HUMAN-Phosphothreonine79 [Term] id: CCO:B0062973 name: NCF1_HUMAN def: "Neutrophil cytosol factor 1" [UniProtKB:P14598] synonym: "47 kDa autosomal chronic granulomatous disease protein" EXACT [UniProtKB:P14598] synonym: "47 kDa neutrophil oxidase factor" EXACT [UniProtKB:P14598] synonym: "NCF-1" EXACT [UniProtKB:P14598] synonym: "NCF-47K" EXACT [UniProtKB:P14598] synonym: "Neutrophil NADPH oxidase factor 1" EXACT [UniProtKB:P14598] synonym: "Nox organizer 2" EXACT [UniProtKB:P14598] synonym: "Nox-organizing protein 2" EXACT [UniProtKB:P14598] synonym: "p47-phox" EXACT [UniProtKB:P14598] synonym: "SH3 and PX domain-containing protein 1A" EXACT [UniProtKB:P14598] xref: EMBL:AAA57209.1 xref: EMBL:AAA59901.1 xref: EMBL:AAA93232.1 xref: EMBL:AAB95193.1 xref: EMBL:AAF34737.1 xref: EMBL:AAH02816.1 xref: EMBL:AAH65731.1 xref: EMBL:AAK19516.1 xref: EMBL:AAK19517.1 xref: EMBL:AAK19518.1 xref: EMBL:AAS07465.1 xref: EMBL:ABC40737.1 xref: EMBL:BAF84783.1 xref: EMBL:BAG54596.1 xref: UniProtKB:A6NEH2 xref: UniProtKB:A8K7S9 xref: UniProtKB:O43842 xref: UniProtKB:P14598 xref: UniProtKB:Q2PP07 xref: UniProtKB:Q9BU90 xref: UniProtKB:Q9BXI7 xref: UniProtKB:Q9BXI8 xref: UniProtKB:Q9UDV9 xref: UniProtKB:Q9UMU2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022430 ! NCF1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015897 ! abi1-ncf1-1 physical interaction relationship: participates_in CCO:I0015918 ! abi1-ncf1-3 physical interaction relationship: participates_in CCO:I0015919 ! abi1-ncf1-4 physical interaction relationship: participates_in CCO:I0016226 ! abi1-ncf1-2 physical interaction relationship: participates_in CCO:I0019227 ! abi1-ncf3-3 physical interaction relationship: transforms_into CCO:B0068456 ! NCF1_HUMAN-Phosphoserine303 relationship: transforms_into CCO:B0068457 ! NCF1_HUMAN-Phosphoserine304 relationship: transforms_into CCO:B0068458 ! NCF1_HUMAN-Phosphoserine320 relationship: transforms_into CCO:B0068459 ! NCF1_HUMAN-Phosphoserine328 relationship: transforms_into CCO:B0068460 ! NCF1_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0068461 ! NCF1_HUMAN-Phosphoserine348 [Term] id: CCO:B0062974 name: BMP1_HUMAN def: "Bone morphogenetic protein 1 precursor" [UniProtKB:P13497] synonym: "BMP-1" EXACT [UniProtKB:P13497] synonym: "EC 3.4.24.19" EXACT [UniProtKB:P13497] synonym: "Mammalian tolloid protein" EXACT [UniProtKB:P13497] synonym: "mTld" EXACT [UniProtKB:P13497] synonym: "PCP" EXACT [UniProtKB:P13497] synonym: "Procollagen C-proteinase" EXACT [UniProtKB:P13497] xref: EMBL:AAA51833.1 xref: EMBL:AAA93462.1 xref: EMBL:AAC41703.1 xref: EMBL:AAC41710.1 xref: EMBL:CAA69973.1 xref: EMBL:CAA69974.1 xref: EMBL:CAA69975.1 xref: UniProtKB:P13497 xref: UniProtKB:Q13292 xref: UniProtKB:Q13872 xref: UniProtKB:Q14874 xref: UniProtKB:Q99421 xref: UniProtKB:Q99422 xref: UniProtKB:Q99423 xref: UniProtKB:Q9UL38 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022073 ! BMP1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001983 ! astacin activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003519 ! procollagen C-endopeptidase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0015910 ! adra1a-bmp1-1 physical interaction [Term] id: CCO:B0062975 name: WASP_HUMAN def: "Wiskott-Aldrich syndrome protein" [UniProtKB:P42768] synonym: "WASp" EXACT [UniProtKB:P42768] xref: EMBL:AAA60381.1 xref: EMBL:AAA62663.1 xref: EMBL:AAC50140.1 xref: EMBL:AAD26691.1 xref: EMBL:AAH02961.1 xref: EMBL:AAH12738.1 xref: UniProtKB:P42768 xref: UniProtKB:Q9BU11 xref: UniProtKB:Q9UNJ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022781 ! WAS_human relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000734 ! vesicle membrane relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: participates_in CCO:I0015937 ! csnk2a1-was-1 phosphorylation relationship: participates_in CCO:I0015938 ! csnk2a1-was-2 phosphorylation relationship: participates_in CCO:I0016236 ! cdc42-was-5 physical interaction relationship: participates_in CCO:I0016278 ! wasp-cdc42-1 direct interaction relationship: participates_in CCO:I0018006 ! cdc42-was-8 physical interaction relationship: participates_in CCO:I0018481 ! cdc42-was-2 direct interaction relationship: participates_in CCO:I0018502 ! wasp-arp2-1 physical interaction relationship: participates_in CCO:I0019236 ! cdc42-was-1 physical interaction relationship: participates_in CCO:I0019237 ! cdc42-was-3 physical interaction relationship: participates_in CCO:I0019346 ! cdc42-was-4 direct interaction relationship: participates_in CCO:I0019350 ! cdc42-was-6 physical interaction relationship: transforms_into CCO:B0071827 ! WASP_HUMAN-Phosphotyrosine291 relationship: transforms_into CCO:B0071828 ! WASP_HUMAN-Phosphoserine483 relationship: transforms_into CCO:B0071829 ! WASP_HUMAN-Phosphoserine484 [Term] id: CCO:B0062976 name: FLOT1_HUMAN def: "Flotillin-1" [UniProtKB:O75955] xref: EMBL:AAC35387.1 xref: EMBL:AAD40192.1 xref: EMBL:AAF17215.1 xref: EMBL:AAH01146.1 xref: EMBL:BAB63320.1 xref: UniProtKB:O75955 xref: UniProtKB:Q969J8 xref: UniProtKB:Q9UHW1 xref: UniProtKB:Q9UNV8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022256 ! FLOT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015940 ! flot1-cav1-1 physical interaction relationship: transforms_into CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 [Term] id: CCO:B0062977 name: FLOT2_HUMAN def: "Flotillin-2" [UniProtKB:Q14254] synonym: "Epidermal surface antigen" EXACT [UniProtKB:Q14254] synonym: "ESA" EXACT [UniProtKB:Q14254] xref: EMBL:AAA65729.1 xref: EMBL:AAH17292.1 xref: EMBL:AAV38285.1 xref: UniProtKB:Q14254 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022257 ! FLOT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015941 ! flot2-cav1-1 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 [Term] id: CCO:B0062978 name: HPS1_HUMAN def: "Hermansky-Pudlak syndrome 1 protein" [UniProtKB:Q92902] xref: EMBL:AAB17869.1 xref: EMBL:AAB70662.1 xref: EMBL:AAC52074.1 xref: EMBL:AAH00175.1 xref: UniProtKB:O15402 xref: UniProtKB:O15502 xref: UniProtKB:Q92902 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022316 ! HPS1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: participates_in CCO:I0015952 ! hsp1-hsp4-11 physical interaction relationship: participates_in CCO:I0015953 ! hsp1-hsp4-12 physical interaction relationship: participates_in CCO:I0016126 ! hsp1-hsp4-1 physical interaction relationship: participates_in CCO:I0016127 ! hsp1-hsp4-2 physical interaction relationship: participates_in CCO:I0016128 ! hsp1-hsp4-14 physical interaction relationship: participates_in CCO:I0017381 ! hsp1-hsp4-3 physical interaction relationship: participates_in CCO:I0017382 ! hsp1-hsp4-4 physical interaction relationship: participates_in CCO:I0017515 ! hsp1-hsp4-9 physical interaction relationship: participates_in CCO:I0018200 ! hsp1-hsp4-8 physical interaction relationship: participates_in CCO:I0018201 ! hsp1-hsp4-10 physical interaction relationship: participates_in CCO:I0018202 ! hsp1-hsp4-15 physical interaction relationship: participates_in CCO:I0018666 ! hsp1-hsp4-7 physical interaction relationship: participates_in CCO:I0018668 ! hsp1-hsp4-13 physical interaction relationship: participates_in CCO:I0019501 ! hsp1-hsp4-5 physical interaction relationship: participates_in CCO:I0019502 ! hsp1-hsp4-6 physical interaction [Term] id: CCO:B0062979 name: GEMI5_HUMAN def: "Gem-associated protein 5" [UniProtKB:Q8TEQ6] synonym: "Gemin5" EXACT [UniProtKB:Q8TEQ6] xref: EMBL:AAH08776.2 xref: EMBL:AAH14147.2 xref: EMBL:AAI13615.1 xref: EMBL:AAL38980.1 xref: EMBL:BAB14222.1 xref: EMBL:BAB84892.1 xref: EMBL:CAB56035.2 xref: UniProtKB:Q14CV0 xref: UniProtKB:Q8TEQ6 xref: UniProtKB:Q8WWV4 xref: UniProtKB:Q969W4 xref: UniProtKB:Q9H9K3 xref: UniProtKB:Q9UFI5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022273 ! GEMIN5_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003544 ! snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000817 ! nuclear body relationship: participates_in CCO:I0015968 ! gemin5-eif4e-1 colocalization relationship: participates_in CCO:I0016318 ! gemin5-eif4e direct interaction relationship: participates_in CCO:I0017671 ! gemin5-ddx20-1 physical interaction relationship: participates_in CCO:I0018600 ! gemin5-gemin4-1 physical interaction relationship: participates_in CCO:I0019445 ! eif4e-gemin5 direct interaction relationship: transforms_into CCO:B0066442 ! GEMI5_HUMAN-Phosphoserine778 relationship: transforms_into CCO:B0066443 ! GEMI5_HUMAN-Phosphothreonine807 relationship: transforms_into CCO:B0066444 ! GEMI5_HUMAN-Phosphoserine1417 [Term] id: CCO:B0062980 name: TRPC6_HUMAN def: "Short transient receptor potential channel 6" [UniProtKB:Q9Y210] synonym: "TrpC6" EXACT [UniProtKB:Q9Y210] xref: EMBL:AAC63289.2 xref: EMBL:AAH93658.1 xref: EMBL:AAH93660.1 xref: EMBL:CAA06943.1 xref: EMBL:CAC01684.1 xref: EMBL:CAC01685.1 xref: EMBL:CAC01686.1 xref: EMBL:CAC06090.1 xref: UniProtKB:Q52M59 xref: UniProtKB:Q9HCW3 xref: UniProtKB:Q9NQA8 xref: UniProtKB:Q9NQA9 xref: UniProtKB:Q9Y210 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022741 ! TRPC6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015971 ! mx1-trpc6-1 physical interaction relationship: participates_in CCO:I0017400 ! mx1-trpc6-4 physical interaction relationship: participates_in CCO:I0017915 ! mx1-trpc6-2 physical interaction relationship: participates_in CCO:I0019449 ! mx1-trpc6-3 physical interaction relationship: transforms_into CCO:B0071583 ! TRPC6_HUMAN-Phosphothreonine70 relationship: transforms_into CCO:B0071584 ! TRPC6_HUMAN-Phosphoserine815 relationship: transforms_into CCO:B0071585 ! TRPC6_HUMAN-Phosphoserine839 [Term] id: CCO:B0062981 name: LAIR1_HUMAN def: "Leukocyte-associated immunoglobulin-like receptor 1 precursor" [UniProtKB:Q6GTX8] synonym: "CD305 antigen" EXACT [UniProtKB:Q6GTX8] synonym: "hLAIR1" EXACT [UniProtKB:Q6GTX8] synonym: "LAIR-1" EXACT [UniProtKB:Q6GTX8] xref: EMBL:AAB69324.1 xref: EMBL:AAF17107.1 xref: EMBL:AAF71274.2 xref: EMBL:AAF71275.2 xref: EMBL:AAH27899.1 xref: EMBL:CAG46848.1 xref: UniProtKB:Q6GTX8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022359 ! LAIR1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0015979 ! ptpn6-lair1-1 physical interaction relationship: transforms_into CCO:B0067518 ! LAIR1_HUMAN-Phosphotyrosine251 relationship: transforms_into CCO:B0067519 ! LAIR1_HUMAN-Phosphotyrosine281 [Term] id: CCO:B0062982 name: DICER_HUMAN def: "Endoribonuclease Dicer" [UniProtKB:Q9UPY3] synonym: "EC 3.1.26.-" EXACT [UniProtKB:Q9UPY3] synonym: "Helicase MOI" EXACT [UniProtKB:Q9UPY3] synonym: "Helicase with RNase motif" EXACT [UniProtKB:Q9UPY3] xref: EMBL:BAA76772.2 xref: EMBL:BAA78691.1 xref: EMBL:CAB38857.2 xref: UniProtKB:O95943 xref: UniProtKB:Q9UPY3 xref: UniProtKB:Q9UQ02 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022188 ! DICER1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0015984 ! dicer1-tarbp2-1 physical interaction relationship: participates_in CCO:I0017368 ! eif2c2-dicer1-2 physical interaction relationship: participates_in CCO:I0017370 ! eif2c2-dicer1-3 physical interaction relationship: participates_in CCO:I0017405 ! dicer1-tarbp2-2 direct interaction relationship: participates_in CCO:I0017406 ! tarbp2-dicer direct interaction relationship: participates_in CCO:I0017701 ! dicer1-eif2c1-2 physical interaction relationship: participates_in CCO:I0018042 ! dicer1-eif2c2-3 physical interaction relationship: participates_in CCO:I0018496 ! dicer1-eif2c2-2 physical interaction relationship: participates_in CCO:I0018499 ! eif2c2-dicer1-1 physical interaction relationship: participates_in CCO:I0018688 ! dicer1-tarbp2-4 physical interaction relationship: participates_in CCO:I0018689 ! dicer1-tarbp2-6 physical interaction relationship: participates_in CCO:I0018795 ! eif2c1-dicer1-1 physical interaction relationship: participates_in CCO:I0019306 ! dicer1-tarbp2-8 physical interaction relationship: participates_in CCO:I0019362 ! dicer1-eif2c2-4 physical interaction relationship: participates_in CCO:I0019459 ! dicer1-tarbp2-3 physical interaction relationship: transforms_into CCO:B0065951 ! DICER_HUMAN-Phosphotyrosine654 relationship: transforms_into CCO:B0065952 ! DICER_HUMAN-Phosphoserine1006 [Term] id: CCO:B0062983 name: NPHN_HUMAN def: "Nephrin precursor" [UniProtKB:O60500] synonym: "Renal glomerulus-specific cell adhesion receptor" EXACT [UniProtKB:O60500] xref: EMBL:AAC39687.1 xref: EMBL:AAF36451.1 xref: EMBL:AAG17141.1 xref: UniProtKB:A6NDH2 xref: UniProtKB:O60500 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022453 ! NPHS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0015995 ! nphs1-nck2 physical interaction relationship: participates_in CCO:I0015996 ! nphs1-nck2-1 colocalization relationship: participates_in CCO:I0016339 ! nck1-nphs1 physical interaction relationship: participates_in CCO:I0016340 ! nck1-nphs1-1 physical interaction relationship: participates_in CCO:I0018108 ! nphs1-nck1 physical interaction relationship: transforms_into CCO:B0068815 ! NPHN_HUMAN-Phosphoserine432 [Term] id: CCO:B0062984 name: LEG4_HUMAN def: "Galectin-4" [UniProtKB:P56470] synonym: "Antigen NY-CO-27" EXACT [UniProtKB:P56470] synonym: "L-36 lactose-binding protein" EXACT [UniProtKB:P56470] synonym: "L36LBP" EXACT [UniProtKB:P56470] synonym: "Lactose-binding lectin 4" EXACT [UniProtKB:P56470] xref: EMBL:AAB86590.1 xref: EMBL:AAC51763.1 xref: EMBL:AAH03661.1 xref: EMBL:AAH05146.1 xref: EMBL:AAH34750.1 xref: EMBL:BAA22165.1 xref: UniProtKB:P56470 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022366 ! LGALS4_human relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: participates_in CCO:I0020358 ! lgals4-arpc3 physical interaction relationship: participates_in CCO:I0020443 ! rras2-lgals4 physical interaction [Term] id: CCO:B0062985 name: PIMT_HUMAN def: "Protein-L-isoaspartate(D-aspartate) O-methyltransferase" [UniProtKB:P22061] synonym: "EC 2.1.1.77" EXACT [UniProtKB:P22061] synonym: "L-isoaspartyl protein carboxyl methyltransferase" EXACT [UniProtKB:P22061] synonym: "PIMT" EXACT [UniProtKB:P22061] synonym: "Protein L-isoaspartyl/D-aspartyl methyltransferase" EXACT [UniProtKB:P22061] synonym: "Protein-beta-aspartate methyltransferase" EXACT [UniProtKB:P22061] xref: EMBL:AAA90933.1 xref: EMBL:AAA90934.1 xref: EMBL:AAB38386.1 xref: EMBL:AAC60639.2 xref: EMBL:AAC60640.1 xref: EMBL:AAC60641.2 xref: EMBL:AAH07501.1 xref: EMBL:AAH08748.1 xref: EMBL:BAA02991.1 xref: EMBL:BAA05028.1 xref: EMBL:BAA05029.1 xref: EMBL:BAA05030.1 xref: EMBL:CAH72862.1 xref: EMBL:CAH72863.1 xref: UniProtKB:P22061 xref: UniProtKB:Q14661 xref: UniProtKB:Q16556 xref: UniProtKB:Q5VYC1 xref: UniProtKB:Q5VYC2 xref: UniProtKB:Q93061 xref: UniProtKB:Q96II9 xref: UniProtKB:Q99625 xref: UniProtKB:Q9BQV7 xref: UniProtKB:Q9BQV8 xref: UniProtKB:Q9NP03 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022515 ! PCMT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0020396 ! pcmt1-chd3 physical interaction relationship: participates_in CCO:I0020618 ! pcmt1-apoa1 physical interaction relationship: transforms_into CCO:B0069309 ! PIMT_HUMAN-N-acetylalanine2 [Term] id: CCO:B0062986 name: VPS4A_HUMAN def: "Vacuolar protein sorting-associating protein 4A" [UniProtKB:Q9UN37] synonym: "hVPS4" EXACT [UniProtKB:Q9UN37] synonym: "Protein SKD2" EXACT [UniProtKB:Q9UN37] synonym: "VPS4-1" EXACT [UniProtKB:Q9UN37] xref: EMBL:AAD42971.1 xref: EMBL:AAD49227.1 xref: EMBL:AAF17203.1 xref: EMBL:AAG01470.1 xref: EMBL:AAH47932.1 xref: EMBL:AAK52408.1 xref: EMBL:AAL75948.1 xref: UniProtKB:Q8TF07 xref: UniProtKB:Q9UI03 xref: UniProtKB:Q9UN37 xref: UniProtKB:Q9Y582 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022779 ! VPS4A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005696 ! ATPase activity, coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction [Term] id: CCO:B0062987 name: F120A_HUMAN def: "Constitutive coactivator of PPAR-gamma-like protein 1" [UniProtKB:Q9NZB2] synonym: "Protein FAM120A" EXACT [UniProtKB:Q9NZB2] xref: EMBL:AAC09364.1 xref: EMBL:AAF72866.1 xref: EMBL:AAF72867.1 xref: EMBL:AAH07879.2 xref: EMBL:AAH98584.1 xref: EMBL:AAI11737.1 xref: EMBL:BAA11500.2 xref: EMBL:CAI96105.1 xref: EMBL:CAI96106.1 xref: EMBL:CAI96108.1 xref: EMBL:CAI96109.1 xref: UniProtKB:A6NGU0 xref: UniProtKB:O60649 xref: UniProtKB:Q14688 xref: UniProtKB:Q4VXF4 xref: UniProtKB:Q4VXF5 xref: UniProtKB:Q4VXG2 xref: UniProtKB:Q96I21 xref: UniProtKB:Q9NZB1 xref: UniProtKB:Q9NZB2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022239 ! FAM120A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: transforms_into CCO:B0066047 ! F120A_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0066048 ! F120A_HUMAN-Phosphoserine383 relationship: transforms_into CCO:B0066049 ! F120A_HUMAN-Phosphotyrosine393 relationship: transforms_into CCO:B0066050 ! F120A_HUMAN-Phosphotyrosine395 relationship: transforms_into CCO:B0066051 ! F120A_HUMAN-Omega-N-methylated arginine982 relationship: transforms_into CCO:B0066052 ! F120A_HUMAN-Phosphothreonine991 relationship: transforms_into CCO:B0066053 ! F120A_HUMAN-Phosphoserine1023 [Term] id: CCO:B0062988 name: COPB_HUMAN def: "Coatomer subunit beta" [UniProtKB:P53618] synonym: "Beta-coat protein" EXACT [UniProtKB:P53618] synonym: "Beta-COP" EXACT [UniProtKB:P53618] xref: EMBL:AAD41240.1 xref: EMBL:AAH37280.1 xref: EMBL:AAL39009.1 xref: EMBL:CAA57622.1 xref: EMBL:CAB66528.1 xref: UniProtKB:P53618 xref: UniProtKB:Q6GTT7 xref: UniProtKB:Q9NTK2 xref: UniProtKB:Q9UNW7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022147 ! COPB1_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000379 ! Golgi-associated vesicle relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000971 ! COPI vesicle coat relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction [Term] id: CCO:B0062989 name: LMNA_HUMAN def: "Lamin-A/C" [UniProtKB:P02545] synonym: "70 kDa lamin" EXACT [UniProtKB:P02545] synonym: "Renal carcinoma antigen NY-REN-32" EXACT [UniProtKB:P02545] xref: EMBL:AAA36160.1 xref: EMBL:AAA36164.1 xref: EMBL:AAH00511.1 xref: EMBL:AAH03162.1 xref: EMBL:AAH14507.1 xref: EMBL:AAK59326.1 xref: EMBL:CAA27173.1 xref: EMBL:CAA27174.1 xref: UniProtKB:P02545 xref: UniProtKB:P02546 xref: UniProtKB:Q969I8 xref: UniProtKB:Q96JA2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022373 ! LMNA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: participates_in CCO:I0019757 ! lmna-htatip physical interaction relationship: transforms_into CCO:B0067691 ! LMNA_HUMAN-Blocked amino end (Met)1 relationship: transforms_into CCO:B0067692 ! LMNA_HUMAN-Phosphothreonine10 relationship: transforms_into CCO:B0067693 ! LMNA_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0067694 ! LMNA_HUMAN-Phosphothreonine19 relationship: transforms_into CCO:B0067695 ! LMNA_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0067696 ! LMNA_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0067697 ! LMNA_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0067698 ! LMNA_HUMAN-Phosphoserine392 relationship: transforms_into CCO:B0067699 ! LMNA_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0067700 ! LMNA_HUMAN-Phosphoserine403 relationship: transforms_into CCO:B0067701 ! LMNA_HUMAN-Phosphoserine404 relationship: transforms_into CCO:B0067702 ! LMNA_HUMAN-Phosphoserine406 relationship: transforms_into CCO:B0067703 ! LMNA_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0067704 ! LMNA_HUMAN-Phosphothreonine409 relationship: transforms_into CCO:B0067705 ! LMNA_HUMAN-Phosphoserine414 relationship: transforms_into CCO:B0067706 ! LMNA_HUMAN-Phosphothreonine416 relationship: transforms_into CCO:B0067707 ! LMNA_HUMAN-N6-acetyllysine417 relationship: transforms_into CCO:B0067708 ! LMNA_HUMAN-Phosphoserine423 relationship: transforms_into CCO:B0067709 ! LMNA_HUMAN-Phosphothreonine424 relationship: transforms_into CCO:B0067710 ! LMNA_HUMAN-Phosphothreonine496 relationship: transforms_into CCO:B0067711 ! LMNA_HUMAN-Phosphothreonine505 relationship: transforms_into CCO:B0067712 ! LMNA_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0067713 ! LMNA_HUMAN-Phosphothreonine510 relationship: transforms_into CCO:B0067714 ! LMNA_HUMAN-Phosphoserine628 relationship: transforms_into CCO:B0067715 ! LMNA_HUMAN-Phosphoserine632 relationship: transforms_into CCO:B0067716 ! LMNA_HUMAN-Phosphoserine636 relationship: transforms_into CCO:B0067717 ! LMNA_HUMAN-Phosphoserine652 [Term] id: CCO:B0062990 name: SFXN3_HUMAN def: "Sideroflexin-3" [UniProtKB:Q9BWM7] xref: EMBL:AAH00124.2 xref: EMBL:BAC11151.1 xref: EMBL:CAI10936.1 xref: UniProtKB:Q8NCJ0 xref: UniProtKB:Q9BWM7 xref: UniProtKB:Q9NTP4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022650 ! SFXN3_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001835 ! cation transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction [Term] id: CCO:B0062991 name: FAT1_HUMAN def: "Protocadherin Fat 1 precursor" [UniProtKB:Q14517] synonym: "Cadherin-related tumor suppressor homolog" EXACT [UniProtKB:Q14517] synonym: "Protein fat homolog" EXACT [UniProtKB:Q14517] xref: EMBL:CAA60685.1 xref: UniProtKB:Q14517 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022251 ! FAT_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: transforms_into CCO:B0066139 ! FAT1_HUMAN-Phosphothreonine152 relationship: transforms_into CCO:B0066140 ! FAT1_HUMAN-Phosphothreonine464 relationship: transforms_into CCO:B0066141 ! FAT1_HUMAN-Phosphotyrosine468 relationship: transforms_into CCO:B0066142 ! FAT1_HUMAN-Phosphotyrosine2604 relationship: transforms_into CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: transforms_into CCO:B0066144 ! FAT1_HUMAN-Phosphothreonine2616 relationship: transforms_into CCO:B0066145 ! FAT1_HUMAN-Phosphoserine4274 [Term] id: CCO:B0062992 name: TRIPC_HUMAN def: "Probable E3 ubiquitin-protein ligase TRIP12" [UniProtKB:Q14669] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q14669] synonym: "Thyroid receptor-interacting protein 12" EXACT [UniProtKB:Q14669] synonym: "TRIP-12" EXACT [UniProtKB:Q14669] xref: EMBL:AAC41731.1 xref: EMBL:BAA05837.2 xref: UniProtKB:Q14669 xref: UniProtKB:Q15644 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022738 ! TRIP12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016007 ! cftr-ebp-3 physical interaction relationship: transforms_into CCO:B0071567 ! TRIPC_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0071568 ! TRIPC_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0071569 ! TRIPC_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0071570 ! TRIPC_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0071571 ! TRIPC_HUMAN-Phosphoserine312 relationship: transforms_into CCO:B0071572 ! TRIPC_HUMAN-Phosphotyrosine507 relationship: transforms_into CCO:B0071573 ! TRIPC_HUMAN-Phosphoserine991 relationship: transforms_into CCO:B0071574 ! TRIPC_HUMAN-Phosphoserine997 relationship: transforms_into CCO:B0071575 ! TRIPC_HUMAN-Phosphoserine1317 relationship: transforms_into CCO:B0071576 ! TRIPC_HUMAN-Phosphoserine1322 relationship: transforms_into CCO:B0071577 ! TRIPC_HUMAN-Phosphoserine1427 relationship: transforms_into CCO:B0071578 ! TRIPC_HUMAN-Phosphoserine1577 relationship: transforms_into CCO:B0071579 ! TRIPC_HUMAN-Phosphothreonine1592 [Term] id: CCO:B0062993 name: MDR1_HUMAN def: "Multidrug resistance protein 1" [UniProtKB:P08183] synonym: "ATP-binding cassette sub-family B member 1" EXACT [UniProtKB:P08183] synonym: "CD243 antigen" EXACT [UniProtKB:P08183] synonym: "EC 3.6.3.44" EXACT [UniProtKB:P08183] synonym: "P-glycoprotein 1" EXACT [UniProtKB:P08183] xref: EMBL:AAA59575.1 xref: EMBL:AAA59576.1 xref: EMBL:AAA88047.1 xref: EMBL:AAA88048.1 xref: EMBL:AAB69423.1 xref: EMBL:AAM49149.1 xref: EMBL:AAW82430.1 xref: EMBL:CAA41558.1 xref: UniProtKB:P08183 xref: UniProtKB:Q12755 xref: UniProtKB:Q14812 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022393 ! ABCB1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001995 ! xenobiotic-transporting ATPase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016009 ! abcb1-rnf2 physical interaction relationship: participates_in CCO:I0017492 ! abcb1-rnf2-1 physical interaction [Term] id: CCO:B0062994 name: ERAP1_HUMAN def: "Endoplasmic reticulum aminopeptidase 1" [UniProtKB:Q9NZ08] synonym: "A-LAP" EXACT [UniProtKB:Q9NZ08] synonym: "Adipocyte-derived leucine aminopeptidase" EXACT [UniProtKB:Q9NZ08] synonym: "Aminopeptidase PILS" EXACT [UniProtKB:Q9NZ08] synonym: "ARTS-1" EXACT [UniProtKB:Q9NZ08] synonym: "EC 3.4.11.-" EXACT [UniProtKB:Q9NZ08] synonym: "PILS-AP" EXACT [UniProtKB:Q9NZ08] synonym: "Puromycin-insensitive leucyl-specific aminopeptidase" EXACT [UniProtKB:Q9NZ08] synonym: "Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator" EXACT [UniProtKB:Q9NZ08] xref: EMBL:AAF07395.1 xref: EMBL:AAF20384.1 xref: EMBL:AAF34664.1 xref: EMBL:AAH30775.1 xref: EMBL:AAK37777.1 xref: EMBL:AAK37778.1 xref: EMBL:AAQ88953.1 xref: EMBL:BAA25451.2 xref: UniProtKB:O60278 xref: UniProtKB:Q6UWY6 xref: UniProtKB:Q8NEL4 xref: UniProtKB:Q8TAD0 xref: UniProtKB:Q9NZ08 xref: UniProtKB:Q9UHF8 xref: UniProtKB:Q9UKY2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022224 ! ERAP1_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0000647 ! leucyl aminopeptidase activity relationship: has_function CCO:F0000648 ! membrane alanyl aminopeptidase activity relationship: has_function CCO:F0000687 ! methionyl aminopeptidase activity relationship: has_function CCO:F0001440 ! interleukin-6 receptor binding relationship: has_function CCO:F0001453 ! interleukin-1, Type II receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016013 ! il6r-arts1 physical interaction relationship: participates_in CCO:I0018767 ! tnfrsf1a-arts1 physical interaction [Term] id: CCO:B0062995 name: RRP5_HUMAN def: "Protein RRP5 homolog" [UniProtKB:Q14690] synonym: "Programmed cell death protein 11" EXACT [UniProtKB:Q14690] xref: EMBL:AAG01992.1 xref: EMBL:AAH49838.1 xref: EMBL:BAA11502.1 xref: EMBL:CAH71487.1 xref: EMBL:CAI15102.1 xref: EMBL:CAI16749.1 xref: EMBL:EAW49641.1 xref: UniProtKB:Q14690 xref: UniProtKB:Q5W093 xref: UniProtKB:Q86VQ8 xref: UniProtKB:Q9H4P1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022608 ! PDCD11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016014 ! nfkb1-pdcd11-2 physical interaction relationship: participates_in CCO:I0016015 ! rela-pdcd11-1 physical interaction relationship: participates_in CCO:I0017841 ! nfkb1-pdcd11-1 physical interaction relationship: transforms_into CCO:B0070197 ! RRP5_HUMAN-Phosphoserine1360 relationship: transforms_into CCO:B0070198 ! RRP5_HUMAN-Phosphoserine1493 relationship: transforms_into CCO:B0070199 ! RRP5_HUMAN-Phosphoserine1498 [Term] id: CCO:B0062996 name: RNF11_HUMAN def: "RING finger protein 11" [UniProtKB:Q9Y3C5] synonym: "Sid 1669" EXACT [UniProtKB:Q9Y3C5] xref: EMBL:AAD34118.1 xref: EMBL:AAH20964.1 xref: EMBL:AAH47654.1 xref: EMBL:BAA84683.1 xref: UniProtKB:Q9Y3C5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022593 ! RNF11_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: participates_in CCO:I0016028 ! rn11-amsh-2 physical interaction relationship: participates_in CCO:I0016029 ! rn11-amsh-3 physical interaction relationship: participates_in CCO:I0016030 ! rn11-suf2-1 physical interaction relationship: participates_in CCO:I0018145 ! rnf11-amsh-1 physical interaction relationship: participates_in CCO:I0018198 ! rnf11-ep15-1 physical interaction [Term] id: CCO:B0062997 name: CLH1_HUMAN def: "Clathrin heavy chain 1" [UniProtKB:Q00610] synonym: "CLH-17" EXACT [UniProtKB:Q00610] xref: EMBL:AAH51800.1 xref: EMBL:AAH54489.1 xref: EMBL:BAA04801.2 xref: EMBL:CAA39363.1 xref: EMBL:CAE45761.1 xref: UniProtKB:Q00610 xref: UniProtKB:Q6N0A0 xref: UniProtKB:Q86TF2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022138 ! CLTC_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000963 ! clathrin coat relationship: located_in CCO:C0000975 ! clathrin coat of trans-Golgi network vesicle relationship: located_in CCO:C0000977 ! clathrin coat of coated pit relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0016036 ! cltc-g22p1 physical interaction relationship: participates_in CCO:I0016360 ! rel-cltc physical interaction relationship: participates_in CCO:I0016380 ! nfkbia-cltc physical interaction relationship: participates_in CCO:I0016402 ! nfkbib-cltc physical interaction relationship: participates_in CCO:I0016438 ! chuk-cltc physical interaction relationship: participates_in CCO:I0016459 ! ikbkb-cltc physical interaction relationship: participates_in CCO:I0016475 ! ikbke-cltc physical interaction relationship: participates_in CCO:I0016523 ! ikbkg-cltc physical interaction relationship: participates_in CCO:I0016579 ! tank-cltc physical interaction relationship: participates_in CCO:I0016708 ! map3k3-cltc physical interaction relationship: participates_in CCO:I0016801 ! nfkb2-cltc-1 physical interaction relationship: participates_in CCO:I0016871 ! relb-cltc physical interaction relationship: participates_in CCO:I0016950 ! q9nyj8-cltc physical interaction relationship: participates_in CCO:I0017012 ! tnfrsf1a-cltc physical interaction relationship: participates_in CCO:I0017074 ! tradd-cltc physical interaction relationship: participates_in CCO:I0017125 ! traf2-cltc physical interaction relationship: transforms_into CCO:B0065881 ! CLH1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0065882 ! CLH1_HUMAN-Phosphothreonine394 relationship: transforms_into CCO:B0065883 ! CLH1_HUMAN-Phosphotyrosine634 relationship: transforms_into CCO:B0065884 ! CLH1_HUMAN-Phosphotyrosine899 relationship: transforms_into CCO:B0065885 ! CLH1_HUMAN-Phosphoserine1494 [Term] id: CCO:B0062998 name: Q9H0V7_HUMAN def: "Putative uncharacterized protein DKFZp564O0523" [UniProtKB:Q9H0V7] xref: EMBL:CAB66554.1 xref: UniProtKB:Q9H0V7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022861 ! DKFZp564O0523_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016040 ! gadd45g-dkfzp564o052 physical interaction [Term] id: CCO:B0062999 name: PR40A_HUMAN def: "Pre-mRNA-processing factor 40 homolog A" [UniProtKB:O75400] synonym: "Fas ligand-associated factor 1" EXACT [UniProtKB:O75400] synonym: "Formin-binding protein 11" EXACT [UniProtKB:O75400] synonym: "Formin-binding protein 3" EXACT [UniProtKB:O75400] synonym: "Huntingtin yeast partner A" EXACT [UniProtKB:O75400] synonym: "Huntingtin-interacting protein A" EXACT [UniProtKB:O75400] synonym: "NY-REN-6 antigen" EXACT [UniProtKB:O75400] xref: EMBL:AAB93495.1 xref: EMBL:AAC27501.1 xref: EMBL:AAC27502.1 xref: EMBL:AAC27506.1 xref: EMBL:AAD42862.1 xref: EMBL:AAF36145.1 xref: EMBL:AAH11788.1 xref: EMBL:AAH27178.1 xref: EMBL:BAA91277.1 xref: EMBL:BAB15016.1 xref: UniProtKB:O43856 xref: UniProtKB:O75400 xref: UniProtKB:O75404 xref: UniProtKB:Q8TBQ1 xref: UniProtKB:Q9H782 xref: UniProtKB:Q9NWU9 xref: UniProtKB:Q9P0Q2 xref: UniProtKB:Q9Y5A8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022527 ! PRPF40A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016055 ! hd-fnbp3 physical interaction relationship: participates_in CCO:I0016056 ! hd-fnbp3-1 physical interaction relationship: participates_in CCO:I0016057 ! hd-fnbp3-2 physical interaction relationship: participates_in CCO:I0016091 ! fnbp3-pias4 physical interaction relationship: participates_in CCO:I0016106 ! fnbp3-zhx1 physical interaction relationship: participates_in CCO:I0019829 ! serpinb9-fnbp3 physical interaction relationship: transforms_into CCO:B0069476 ! PR40A_HUMAN-Phosphoserine34 relationship: transforms_into CCO:B0069477 ! PR40A_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0069478 ! PR40A_HUMAN-Phosphothreonine373 relationship: transforms_into CCO:B0069479 ! PR40A_HUMAN-Phosphoserine883 relationship: transforms_into CCO:B0069480 ! PR40A_HUMAN-Phosphoserine885 relationship: transforms_into CCO:B0069481 ! PR40A_HUMAN-Phosphoserine888 relationship: transforms_into CCO:B0069482 ! PR40A_HUMAN-Phosphothreonine932 relationship: transforms_into CCO:B0069483 ! PR40A_HUMAN-Phosphoserine933 relationship: transforms_into CCO:B0069484 ! PR40A_HUMAN-Phosphoserine935 relationship: transforms_into CCO:B0069485 ! PR40A_HUMAN-Phosphoserine938 [Term] id: CCO:B0063000 name: SUMO3_HUMAN def: "Small ubiquitin-related modifier 3 precursor" [UniProtKB:P55854] synonym: "SMT3 homolog 1" EXACT [UniProtKB:P55854] synonym: "SUMO-2" EXACT [UniProtKB:P55854] synonym: "SUMO-3" EXACT [UniProtKB:P55854] synonym: "Ubiquitin-like protein SMT3A" EXACT [UniProtKB:P55854] xref: EMBL:AAH00036.1 xref: EMBL:AAH08420.1 xref: EMBL:AAP35654.1 xref: EMBL:BAD96311.1 xref: EMBL:CAA67896.1 xref: EMBL:CAG46970.1 xref: EMBL:CAG46985.1 xref: UniProtKB:P55854 xref: UniProtKB:Q53HI9 xref: UniProtKB:Q6FGD4 xref: UniProtKB:Q9BWR4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022686 ! SUMO3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016098 ! pias4-smt3h1 physical interaction [Term] id: CCO:B0063001 name: SUMO2_HUMAN def: "Small ubiquitin-related modifier 2 precursor" [UniProtKB:P61956] synonym: "HSMT3" EXACT [UniProtKB:P61956] synonym: "Sentrin-2" EXACT [UniProtKB:P61956] synonym: "SMT3 homolog 2" EXACT [UniProtKB:P61956] synonym: "SUMO-2" EXACT [UniProtKB:P61956] synonym: "SUMO-3" EXACT [UniProtKB:P61956] synonym: "Ubiquitin-like protein SMT3B" EXACT [UniProtKB:P61956] xref: EMBL:AAD45399.1 xref: EMBL:AAH08450.1 xref: EMBL:AAH16775.1 xref: EMBL:AAH22340.1 xref: EMBL:AAH62713.1 xref: EMBL:AAH68465.1 xref: EMBL:AAH70159.1 xref: EMBL:AAH71645.1 xref: EMBL:AAH71646.1 xref: EMBL:AAI07854.1 xref: EMBL:CAA67897.1 xref: UniProtKB:P55855 xref: UniProtKB:P61956 xref: UniProtKB:Q32Q42 xref: UniProtKB:Q6IPZ6 xref: UniProtKB:Q96HK1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022685 ! SUMO2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016099 ! pias4-smt3h2 physical interaction relationship: participates_in CCO:I0016100 ! smt3h2-setdb1 physical interaction relationship: participates_in CCO:I0016119 ! pias4-smt3h2-1 physical interaction relationship: participates_in CCO:I0018165 ! smt3h2-pias4 physical interaction relationship: participates_in CCO:I0019552 ! sumo2-chd3 physical interaction relationship: participates_in CCO:I0019631 ! timp1-sumo2 physical interaction relationship: participates_in CCO:I0019948 ! chn2-sumo2 physical interaction relationship: participates_in CCO:I0020052 ! lama4-sumo2 physical interaction relationship: participates_in CCO:I0020112 ! plaur-sumo2 physical interaction relationship: participates_in CCO:I0020454 ! sumo2-maf1 physical interaction relationship: participates_in CCO:I0020654 ! rnf2-sumo2 physical interaction [Term] id: CCO:B0063002 name: MBD4_HUMAN def: "Methyl-CpG-binding domain protein 4" [UniProtKB:O95243] synonym: "EC 3.2.2.-" EXACT [UniProtKB:O95243] synonym: "Methyl-CpG-binding endonuclease 1" EXACT [UniProtKB:O95243] synonym: "Methyl-CpG-binding protein MBD4" EXACT [UniProtKB:O95243] synonym: "Mismatch-specific DNA N-glycosylase" EXACT [UniProtKB:O95243] xref: EMBL:AAC68879.1 xref: EMBL:AAD22195.1 xref: EMBL:AAD50374.1 xref: EMBL:AAH11752.1 xref: EMBL:AAM00008.1 xref: EMBL:AAP97338.1 xref: EMBL:CAG29301.1 xref: UniProtKB:O95243 xref: UniProtKB:Q7Z4T3 xref: UniProtKB:Q96F09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022390 ! MBD4_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000287 ! satellite DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000917 ! endodeoxyribonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016112 ! fadd-mbd4 physical interaction relationship: participates_in CCO:I0016255 ! fadd-mbd4-1 physical interaction relationship: participates_in CCO:I0016256 ! mbd4-fadd-1 physical interaction relationship: participates_in CCO:I0018310 ! fadd-mbd4-3 physical interaction relationship: participates_in CCO:I0018459 ! csnk2b-mbd4 physical interaction relationship: participates_in CCO:I0018786 ! mbd4-fadd physical interaction relationship: participates_in CCO:I0018787 ! fadd-mbd4-2 physical interaction [Term] id: CCO:B0063003 name: SNRPA_HUMAN def: "U1 small nuclear ribonucleoprotein A" [UniProtKB:P09012] synonym: "U1 snRNP protein A" EXACT [UniProtKB:P09012] synonym: "U1-A" EXACT [UniProtKB:P09012] synonym: "U1A protein" EXACT [UniProtKB:P09012] xref: EMBL:AAA61245.1 xref: EMBL:AAH00405.1 xref: EMBL:AAH08290.1 xref: EMBL:CAA29653.1 xref: UniProtKB:P09012 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022661 ! SNRPA_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0016121 ! snrpa-sfpq-1 physical interaction relationship: participates_in CCO:I0018503 ! snrpa-sfpq-4 physical interaction relationship: participates_in CCO:I0018827 ! snrpa-sfpq-3 physical interaction relationship: participates_in CCO:I0019497 ! snrpa-sfpq-2 physical interaction relationship: transforms_into CCO:B0070696 ! SNRPA_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063004 name: RANB9_HUMAN def: "Ran-binding protein 9" [UniProtKB:Q96S59] synonym: "BPM-L" EXACT [UniProtKB:Q96S59] synonym: "BPM90" EXACT [UniProtKB:Q96S59] synonym: "Ran-binding protein M" EXACT [UniProtKB:Q96S59] synonym: "RanBP7" EXACT [UniProtKB:Q96S59] synonym: "RanBP9" EXACT [UniProtKB:Q96S59] synonym: "RanBPM" EXACT [UniProtKB:Q96S59] xref: EMBL:AAH19886.1 xref: EMBL:AAH52781.1 xref: EMBL:AAH63849.1 xref: EMBL:AAK15469.1 xref: EMBL:BAA23216.1 xref: EMBL:BAB62525.1 xref: EMBL:CAI19841.1 xref: EMBL:CAI21594.1 xref: UniProtKB:A0PJA2 xref: UniProtKB:O94764 xref: UniProtKB:Q6P3T7 xref: UniProtKB:Q7LBR2 xref: UniProtKB:Q7Z7F9 xref: UniProtKB:Q96S59 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022557 ! RANBP9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001985 ! Ran GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0016123 ! dyrk1b-ranbp9-3 physical interaction relationship: participates_in CCO:I0016287 ! dyrk1b-ranbp9-2 direct interaction relationship: participates_in CCO:I0018066 ! dyrk1b-ranbp9-4 physical interaction relationship: participates_in CCO:I0019499 ! dyrk1b-ranbp9-1 physical interaction relationship: transforms_into CCO:B0069731 ! RANB9_HUMAN-Phosphoserine603 [Term] id: CCO:B0063005 name: GAN_HUMAN def: "Gigaxonin" [UniProtKB:Q9H2C0] synonym: "Kelch-like protein 16" EXACT [UniProtKB:Q9H2C0] xref: EMBL:AAG35311.1 xref: EMBL:AAH44840.1 xref: UniProtKB:Q9H2C0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022267 ! GAN_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000441 ! neurofilament relationship: participates_in CCO:I0016135 ! gan-map1b physical interaction relationship: participates_in CCO:I0017764 ! gan-map1b-1 physical interaction relationship: participates_in CCO:I0019282 ! gan-map1b-2 physical interaction relationship: transforms_into CCO:B0066364 ! GAN_HUMAN-Phosphotyrosine471 [Term] id: CCO:B0063006 name: ANTR1_HUMAN def: "Anthrax toxin receptor 1 precursor" [UniProtKB:Q9H6X2] synonym: "Tumor endothelial marker 8" EXACT [UniProtKB:Q9H6X2] xref: EMBL:AAH12074.1 xref: EMBL:AAK52094.1 xref: EMBL:AAL26496.1 xref: EMBL:BAA91707.1 xref: EMBL:BAB15128.1 xref: UniProtKB:Q96P02 xref: UniProtKB:Q9H6X2 xref: UniProtKB:Q9NVP3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022034 ! ANTXR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016146 ! lrp6-tem8 physical interaction relationship: participates_in CCO:I0016147 ! lrp6-tem8-1 physical interaction relationship: participates_in CCO:I0016148 ! lrp6-tem8-2 physical interaction relationship: transforms_into CCO:B0065647 ! ANTR1_HUMAN-Phosphoserine362 relationship: transforms_into CCO:B0065648 ! ANTR1_HUMAN-Phosphotyrosine425 [Term] id: CCO:B0063007 name: ANTR2_HUMAN def: "Anthrax toxin receptor 2 precursor" [UniProtKB:P58335] synonym: "Capillary morphogenesis gene 2 protein" EXACT [UniProtKB:P58335] synonym: "CMG-2" EXACT [UniProtKB:P58335] xref: EMBL:AAH34001.1 xref: EMBL:AAK77222.1 xref: EMBL:AAP04016.1 xref: EMBL:BAB70976.1 xref: EMBL:BAC03731.1 xref: EMBL:BAD93150.1 xref: EMBL:CAI46157.2 xref: UniProtKB:P58335 xref: UniProtKB:Q59E98 xref: UniProtKB:Q5JPE9 xref: UniProtKB:Q86UI1 xref: UniProtKB:Q8N4J8 xref: UniProtKB:Q8NB13 xref: UniProtKB:Q96NC7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022035 ! ANTXR2_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016149 ! lrp6-cmg2 physical interaction relationship: participates_in CCO:I0017909 ! lrp6-cmg2-1 colocalization [Term] id: CCO:B0063008 name: WIPF1_HUMAN def: "WAS/WASL-interacting protein family member 1" [UniProtKB:O43516] synonym: "Protein PRPL-2" EXACT [UniProtKB:O43516] synonym: "WASP-interacting protein" EXACT [UniProtKB:O43516] synonym: "Wiskott-Aldrich syndrome protein-interacting protein" EXACT [UniProtKB:O43516] xref: EMBL:AAC03767.1 xref: EMBL:AAD45972.1 xref: EMBL:AAH02914.1 xref: EMBL:AAY14708.1 xref: EMBL:CAA60014.1 xref: EMBL:CAE45928.1 xref: UniProtKB:O43516 xref: UniProtKB:Q15220 xref: UniProtKB:Q53TA9 xref: UniProtKB:Q6MZU9 xref: UniProtKB:Q9BU37 xref: UniProtKB:Q9UNP1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022787 ! WIPF1_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001653 ! profilin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0016151 ! nck1-waspip-3 physical interaction relationship: participates_in CCO:I0017910 ! nck1-waspip-2 physical interaction relationship: transforms_into CCO:B0071843 ! WIPF1_HUMAN-Phosphoserine350 [Term] id: CCO:B0063009 name: CA094_HUMAN def: "Uncharacterized protein C1orf94" [UniProtKB:Q6P1W5] xref: EMBL:AAH07637.1 xref: EMBL:AAH64845.1 xref: UniProtKB:Q6P1W5 xref: UniProtKB:Q96IC8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022080 ! C1orf94_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016168 ! atxn1-c1orf94 physical interaction relationship: participates_in CCO:I0017627 ! c1orf94-atxn1 physical interaction relationship: participates_in CCO:I0017630 ! atxn1-c1orf94-1 physical interaction [Term] id: CCO:B0063010 name: PKHA5_HUMAN def: "Pleckstrin homology domain-containing family A member 5" [UniProtKB:Q9HAU0] synonym: "PEPP-2" EXACT [UniProtKB:Q9HAU0] synonym: "Phosphoinositol 3-phosphate-binding protein 2" EXACT [UniProtKB:Q9HAU0] xref: EMBL:AAG22817.1 xref: EMBL:AAH00969.1 xref: EMBL:AAH13133.3 xref: EMBL:AAI27093.1 xref: EMBL:BAA91742.1 xref: EMBL:BAB14419.1 xref: EMBL:BAB21777.2 xref: EMBL:CAD38934.1 xref: UniProtKB:A0JP03 xref: UniProtKB:Q8N3K6 xref: UniProtKB:Q96DY9 xref: UniProtKB:Q9BVR4 xref: UniProtKB:Q9C0H7 xref: UniProtKB:Q9H924 xref: UniProtKB:Q9HAU0 xref: UniProtKB:Q9NVK8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022517 ! PLEKHA5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016169 ! atxn1-plekha5 physical interaction relationship: participates_in CCO:I0017605 ! atxn1-plekha5-1 physical interaction relationship: transforms_into CCO:B0069330 ! PKHA5_HUMAN-Phosphotyrosine128 relationship: transforms_into CCO:B0069331 ! PKHA5_HUMAN-Phosphotyrosine134 relationship: transforms_into CCO:B0069332 ! PKHA5_HUMAN-Phosphothreonine438 relationship: transforms_into CCO:B0069333 ! PKHA5_HUMAN-Phosphothreonine476 relationship: transforms_into CCO:B0069334 ! PKHA5_HUMAN-Phosphoserine568 relationship: transforms_into CCO:B0069335 ! PKHA5_HUMAN-Phosphoserine855 relationship: transforms_into CCO:B0069336 ! PKHA5_HUMAN-Phosphothreonine857 relationship: transforms_into CCO:B0069337 ! PKHA5_HUMAN-Phosphoserine933 relationship: transforms_into CCO:B0069338 ! PKHA5_HUMAN-Phosphoserine937 [Term] id: CCO:B0063011 name: U2AF2_HUMAN def: "Splicing factor U2AF 65 kDa subunit" [UniProtKB:P26368] synonym: "hU2AF(65)" EXACT [UniProtKB:P26368] synonym: "hU2AF65" EXACT [UniProtKB:P26368] synonym: "U2 auxiliary factor 65 kDa subunit" EXACT [UniProtKB:P26368] synonym: "U2 snRNP auxiliary factor large subunit" EXACT [UniProtKB:P26368] xref: EMBL:AAH08740.1 xref: EMBL:AAH30574.1 xref: EMBL:CAA45409.1 xref: EMBL:EAW72404.1 xref: UniProtKB:P26368 xref: UniProtKB:Q96HC5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022751 ! U2AF2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016175 ! atxn1-u2af2 physical interaction relationship: participates_in CCO:I0017568 ! u2af2-atxn1 physical interaction relationship: participates_in CCO:I0017611 ! atxn1-u2af2-2 physical interaction relationship: participates_in CCO:I0019108 ! atxn1-u2af2-1 physical interaction relationship: transforms_into CCO:B0071651 ! U2AF2_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0071652 ! U2AF2_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0071653 ! U2AF2_HUMAN-Phosphoserine53 relationship: transforms_into CCO:B0071654 ! U2AF2_HUMAN-Phosphoserine55 relationship: transforms_into CCO:B0071655 ! U2AF2_HUMAN-Phosphoserine79 [Term] id: CCO:B0063012 name: YYAP1_HUMAN def: "YY1-associated protein 1" [UniProtKB:Q9H869] synonym: "Hepatocellular carcinoma susceptibility protein" EXACT [UniProtKB:Q9H869] synonym: "Hepatocellular carcinoma-associated protein 2" EXACT [UniProtKB:Q9H869] xref: EMBL:AAH01655.2 xref: EMBL:AAH01843.2 xref: EMBL:AAH08766.2 xref: EMBL:AAH09358.2 xref: EMBL:AAH14906.1 xref: EMBL:AAL74055.1 xref: EMBL:AAL75971.1 xref: EMBL:AAO13249.1 xref: EMBL:AAT34990.1 xref: EMBL:BAA91871.1 xref: EMBL:BAB14748.1 xref: EMBL:CAH71642.1 xref: EMBL:CAH71643.1 xref: EMBL:CAH71644.1 xref: EMBL:CAH71646.1 xref: EMBL:CAH73350.1 xref: EMBL:CAH73351.1 xref: EMBL:CAH73352.1 xref: EMBL:CAH73354.1 xref: UniProtKB:Q5VYZ4 xref: UniProtKB:Q5VYZ7 xref: UniProtKB:Q7L4C3 xref: UniProtKB:Q7L5E2 xref: UniProtKB:Q8IXA6 xref: UniProtKB:Q8TEW5 xref: UniProtKB:Q8TF04 xref: UniProtKB:Q96HB6 xref: UniProtKB:Q9BQ64 xref: UniProtKB:Q9H869 xref: UniProtKB:Q9NV84 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022792 ! YY1AP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016182 ! atxn1-yy1ap1 physical interaction relationship: participates_in CCO:I0018960 ! atxn1-yy1ap1-1 physical interaction relationship: participates_in CCO:I0018985 ! atxn1-yy1ap1-2 physical interaction relationship: participates_in CCO:I0019068 ! atxn1-yy1ap1-3 physical interaction relationship: transforms_into CCO:B0071930 ! YYAP1_HUMAN-Phosphoserine724 [Term] id: CCO:B0063013 name: CIC_HUMAN def: "Protein capicua homolog" [UniProtKB:Q96RK0] xref: EMBL:AAD11988.1 xref: EMBL:AAK73515.1 xref: EMBL:BAA20765.1 xref: UniProtKB:Q7LGI1 xref: UniProtKB:Q96RK0 xref: UniProtKB:Q9UEG5 xref: UniProtKB:Q9Y6T1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022125 ! CIC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016187 ! cenpj-cic physical interaction relationship: participates_in CCO:I0017572 ! trim22-cic physical interaction relationship: participates_in CCO:I0017573 ! znrd1-cic physical interaction relationship: participates_in CCO:I0017618 ! cic-gabpb2 physical interaction relationship: participates_in CCO:I0018948 ! atxn1-cic physical interaction relationship: participates_in CCO:I0018968 ! atxn1-cic-1 physical interaction relationship: participates_in CCO:I0018991 ! atxn1-cic-2 physical interaction relationship: participates_in CCO:I0019025 ! atxn1-cic-3 physical interaction relationship: participates_in CCO:I0019129 ! cic-atxn1 physical interaction relationship: participates_in CCO:I0019130 ! cic-cenpj physical interaction relationship: participates_in CCO:I0019131 ! cic-prkcabp physical interaction relationship: transforms_into CCO:B0065860 ! CIC_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0065861 ! CIC_HUMAN-Phosphoserine904 relationship: transforms_into CCO:B0065862 ! CIC_HUMAN-Phosphothreonine1291 relationship: transforms_into CCO:B0065863 ! CIC_HUMAN-Phosphoserine1294 relationship: transforms_into CCO:B0065864 ! CIC_HUMAN-Phosphoserine1373 relationship: transforms_into CCO:B0065865 ! CIC_HUMAN-Phosphoserine1378 relationship: transforms_into CCO:B0065866 ! CIC_HUMAN-Phosphoserine1382 relationship: transforms_into CCO:B0065867 ! CIC_HUMAN-Phosphoserine1397 relationship: transforms_into CCO:B0065868 ! CIC_HUMAN-Phosphoserine1402 relationship: transforms_into CCO:B0065869 ! CIC_HUMAN-Phosphoserine1409 relationship: transforms_into CCO:B0065870 ! CIC_HUMAN-Phosphoserine1462 [Term] id: CCO:B0063014 name: AHSA1_HUMAN def: "Activator of 90 kDa heat shock protein ATPase homolog 1" [UniProtKB:O95433] synonym: "AHA1" EXACT [UniProtKB:O95433] synonym: "p38" EXACT [UniProtKB:O95433] xref: EMBL:AAD09623.1 xref: EMBL:AAF29000.1 xref: EMBL:AAF80755.1 xref: EMBL:AAH00321.1 xref: EMBL:AAH07398.2 xref: EMBL:CAB45684.1 xref: UniProtKB:O95433 xref: UniProtKB:Q96IL6 xref: UniProtKB:Q9P060 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022029 ! AHSA1_human relationship: has_function CCO:F0000200 ! ATPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004342 ! chaperone activator activity relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0016191 ! gch1-aha1-2 physical interaction relationship: participates_in CCO:I0018231 ! gch1-aha1-1 physical interaction relationship: participates_in CCO:I0018298 ! ahsa1-hspca-1 physical interaction relationship: participates_in CCO:I0018627 ! gch1-aha1 physical interaction [Term] id: CCO:B0063015 name: TMEDA_HUMAN def: "Transmembrane emp24 domain-containing protein 10 precursor" [UniProtKB:P49755] synonym: "21 kDa transmembrane-trafficking protein" EXACT [UniProtKB:P49755] synonym: "p24delta" EXACT [UniProtKB:P49755] synonym: "S31I125" EXACT [UniProtKB:P49755] synonym: "S31III125" EXACT [UniProtKB:P49755] synonym: "Tmp-21-I" EXACT [UniProtKB:P49755] synonym: "Transmembrane protein Tmp21" EXACT [UniProtKB:P49755] xref: EMBL:AAB03625.1 xref: EMBL:AAC42003.1 xref: EMBL:AAD31941.1 xref: EMBL:AAH01496.1 xref: EMBL:AAH01825.1 xref: EMBL:CAA06213.1 xref: EMBL:CAA66071.1 xref: EMBL:CAA66073.1 xref: EMBL:CAD66561.1 xref: EMBL:CAD89913.1 xref: UniProtKB:P49755 xref: UniProtKB:Q15602 xref: UniProtKB:Q16536 xref: UniProtKB:Q86TC2 xref: UniProtKB:Q86TS5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022719 ! TMED10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016196 ! tmed10-psen1-4 physical interaction relationship: participates_in CCO:I0017773 ! tmed10-psen1-3 physical interaction relationship: participates_in CCO:I0017774 ! tmed10-ncstn-2 physical interaction relationship: participates_in CCO:I0017775 ! tmed10-psenen-2 physical interaction relationship: participates_in CCO:I0018565 ! tmed10-psen1-5 physical interaction relationship: participates_in CCO:I0018697 ! tmed10-psen1 physical interaction relationship: participates_in CCO:I0018884 ! tmed10-psen1-1 physical interaction relationship: participates_in CCO:I0018885 ! tmed10-ncstn physical interaction relationship: participates_in CCO:I0018886 ! tmed10-psenen physical interaction relationship: transforms_into CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 relationship: transforms_into CCO:B0071422 ! TMEDA_HUMAN-Omega-N-methylated arginine176 [Term] id: CCO:B0063016 name: NCBP2_HUMAN def: "Nuclear cap-binding protein subunit 2" [UniProtKB:P52298] synonym: "20 kDa nuclear cap-binding protein" EXACT [UniProtKB:P52298] synonym: "CBP20" EXACT [UniProtKB:P52298] synonym: "Cell proliferation-inducing gene 55 protein" EXACT [UniProtKB:P52298] synonym: "NCBP 20 kDa subunit" EXACT [UniProtKB:P52298] synonym: "NCBP-interacting protein 1" EXACT [UniProtKB:P52298] synonym: "NIP1" EXACT [UniProtKB:P52298] xref: EMBL:AAH01255.1 xref: EMBL:AAP35488.1 xref: EMBL:AAV85455.1 xref: EMBL:BAA09599.1 xref: EMBL:CAA58962.1 xref: UniProtKB:P52298 xref: UniProtKB:Q14924 xref: UniProtKB:Q2TS50 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022429 ! NCBP2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000071 ! RNA cap binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0002172 ! mRNA cap binding complex relationship: participates_in CCO:I0016200 ! ncbp1-ncbp2-1 direct interaction relationship: participates_in CCO:I0016201 ! ncbp1-ncbp2-2 direct interaction relationship: participates_in CCO:I0016202 ! ncbp1-ncbp2-3 direct interaction relationship: participates_in CCO:I0018150 ! eif4gi-ncbp2 physical interaction relationship: participates_in CCO:I0018151 ! eif4gi-ncbp1 physical interaction relationship: participates_in CCO:I0018250 ! ncbp1-ncbp2-4 direct interaction relationship: participates_in CCO:I0018251 ! ncbp1-ncbp2-5 direct interaction relationship: transforms_into CCO:B0068454 ! NCBP2_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0068455 ! NCBP2_HUMAN-Phosphoserine18 [Term] id: CCO:B0063017 name: H31T_HUMAN def: "Histone H3.1t" [UniProtKB:Q16695] synonym: "H3/g" EXACT [UniProtKB:Q16695] synonym: "H3/t" EXACT [UniProtKB:Q16695] synonym: "H3t" EXACT [UniProtKB:Q16695] xref: EMBL:AAH69079.1 xref: EMBL:AAI01838.1 xref: EMBL:AAI01840.1 xref: EMBL:AAN39284.1 xref: EMBL:CAA90020.1 xref: EMBL:CAG46810.1 xref: EMBL:CAI23333.1 xref: UniProtKB:Q16695 xref: UniProtKB:Q6FGU4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022299 ! HIST3H3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016211 ! h3_peptide-fbxl11 direct interaction relationship: participates_in CCO:I0017026 ! tnfrsf1a-hist3h3 physical interaction relationship: transforms_into CCO:B0066722 ! H31T_HUMAN-Phosphothreonine4 relationship: transforms_into CCO:B0066723 ! H31T_HUMAN-N6-methylated lysine5 relationship: transforms_into CCO:B0066724 ! H31T_HUMAN-Citrulline9 relationship: transforms_into CCO:B0066725 ! H31T_HUMAN-dimethylarginine9 relationship: transforms_into CCO:B0066726 ! H31T_HUMAN-N6-acetyllysine10 relationship: transforms_into CCO:B0066727 ! H31T_HUMAN-lysine10 relationship: transforms_into CCO:B0066728 ! H31T_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0066729 ! H31T_HUMAN-Phosphothreonine12 relationship: transforms_into CCO:B0066730 ! H31T_HUMAN-N6-acetyllysine15 relationship: transforms_into CCO:B0066731 ! H31T_HUMAN-dimethylarginine18 relationship: transforms_into CCO:B0066732 ! H31T_HUMAN-Citrulline18 relationship: transforms_into CCO:B0066733 ! H31T_HUMAN-N6-acetyllysine19 relationship: transforms_into CCO:B0066734 ! H31T_HUMAN-lysine19 relationship: transforms_into CCO:B0066735 ! H31T_HUMAN-N6-acetyllysine24 relationship: transforms_into CCO:B0066736 ! H31T_HUMAN-N6-acetyllysine28 relationship: transforms_into CCO:B0066737 ! H31T_HUMAN-lysine28 relationship: transforms_into CCO:B0066738 ! H31T_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0066739 ! H31T_HUMAN-N6-acetyllysine37 relationship: transforms_into CCO:B0066740 ! H31T_HUMAN-lysine37 relationship: transforms_into CCO:B0066741 ! H31T_HUMAN-N6-methylated lysine65 relationship: transforms_into CCO:B0066742 ! H31T_HUMAN-N6-methylated lysine80 relationship: transforms_into CCO:B0066743 ! H31T_HUMAN-N6-methylated lysine123 [Term] id: CCO:B0063018 name: CDR2_HUMAN def: "Cerebellar degeneration-related protein 2" [UniProtKB:Q01850] synonym: "Major Yo paraneoplastic antigen" EXACT [UniProtKB:Q01850] synonym: "Paraneoplastic cerebellar degeneration-associated antigen" EXACT [UniProtKB:Q01850] xref: EMBL:AAA51961.1 xref: EMBL:AAB20813.1 xref: EMBL:AAH17503.2 xref: EMBL:BAA02360.1 xref: UniProtKB:Q01850 xref: UniProtKB:Q13977 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022111 ! CDR2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016212 ! morf4l2-cdr2-3 direct interaction relationship: participates_in CCO:I0018269 ! cdr2-morf4l2-1 direct interaction relationship: participates_in CCO:I0018406 ! morf4l2-cdr2-1 physical interaction relationship: participates_in CCO:I0018407 ! morf4l2-cdr2-2 physical interaction relationship: participates_in CCO:I0018760 ! cdr2-morf4l2-2 physical interaction relationship: participates_in CCO:I0019479 ! cdr2-morf4l2 direct interaction [Term] id: CCO:B0063019 name: QSK_HUMAN def: "Serine/threonine-protein kinase QSK" [UniProtKB:Q9Y2K2] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9Y2K2] synonym: "Salt-inducible kinase 3" EXACT [UniProtKB:Q9Y2K2] synonym: "SIK-3" EXACT [UniProtKB:Q9Y2K2] synonym: "SIK3" EXACT [UniProtKB:Q9Y2K2] xref: EMBL:AAH35583.3 xref: EMBL:AAH63887.1 xref: EMBL:AAH86858.1 xref: EMBL:AAT06749.1 xref: EMBL:BAA76843.2 xref: EMBL:BAB14006.1 xref: EMBL:BAD92564.1 xref: UniProtKB:Q59FY2 xref: UniProtKB:Q5M9N1 xref: UniProtKB:Q6P3R6 xref: UniProtKB:Q8IYM8 xref: UniProtKB:Q9HA50 xref: UniProtKB:Q9Y2K2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022550 ! QSK_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006258 ! qsk-ywhaz-3 physical interaction relationship: participates_in CCO:I0007837 ! qsk-ywhaz-2 physical interaction relationship: participates_in CCO:I0017827 ! qsk-ywhaz-4 direct interaction relationship: participates_in CCO:I0018268 ! qsk-ywhaz-1 physical interaction relationship: participates_in CCO:I0018274 ! qsk-ywhaz-5 direct interaction relationship: transforms_into CCO:B0069657 ! QSK_HUMAN-Phosphothreonine163 relationship: transforms_into CCO:B0069658 ! QSK_HUMAN-Phosphoserine167 relationship: transforms_into CCO:B0069659 ! QSK_HUMAN-Phosphoserine533 relationship: transforms_into CCO:B0069660 ! QSK_HUMAN-Phosphoserine534 relationship: transforms_into CCO:B0069661 ! QSK_HUMAN-Phosphoserine568 [Term] id: CCO:B0063020 name: NU107_HUMAN def: "Nuclear pore complex protein Nup107" [UniProtKB:P57740] synonym: "107 kDa nucleoporin" EXACT [UniProtKB:P57740] synonym: "Nucleoporin Nup107" EXACT [UniProtKB:P57740] xref: EMBL:AAH43343.1 xref: EMBL:CAC03716.1 xref: UniProtKB:P57740 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022461 ! NUP107_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016215 ! nup107-nup160-1 physical interaction relationship: transforms_into CCO:B0068892 ! NU107_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0068893 ! NU107_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0068894 ! NU107_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0068895 ! NU107_HUMAN-Phosphothreonine46 relationship: transforms_into CCO:B0068896 ! NU107_HUMAN-Phosphothreonine55 relationship: transforms_into CCO:B0068897 ! NU107_HUMAN-Phosphoserine58 relationship: transforms_into CCO:B0068898 ! NU107_HUMAN-Phosphothreonine64 relationship: transforms_into CCO:B0068899 ! NU107_HUMAN-Phosphoserine69 relationship: transforms_into CCO:B0068900 ! NU107_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0068901 ! NU107_HUMAN-Phosphoserine86 [Term] id: CCO:B0063021 name: NU133_HUMAN def: "Nuclear pore complex protein Nup133" [UniProtKB:Q8WUM0] synonym: "133 kDa nucleoporin" EXACT [UniProtKB:Q8WUM0] synonym: "Nucleoporin Nup133" EXACT [UniProtKB:Q8WUM0] xref: EMBL:AAH20107.1 xref: EMBL:BAA91829.1 xref: EMBL:BAA91885.1 xref: EMBL:BAB14106.1 xref: EMBL:CAI19048.1 xref: EMBL:CAI22011.1 xref: EMBL:CAI22354.1 xref: UniProtKB:Q5T8N0 xref: UniProtKB:Q8WUM0 xref: UniProtKB:Q9H9W2 xref: UniProtKB:Q9NV71 xref: UniProtKB:Q9NVC4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022462 ! NUP133_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016216 ! nup133-nup160-1 physical interaction relationship: transforms_into CCO:B0068902 ! NU133_HUMAN-Phosphoserine27 relationship: transforms_into CCO:B0068903 ! NU133_HUMAN-Phosphothreonine28 relationship: transforms_into CCO:B0068904 ! NU133_HUMAN-Phosphoserine41 relationship: transforms_into CCO:B0068905 ! NU133_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0068906 ! NU133_HUMAN-Phosphoserine50 relationship: transforms_into CCO:B0068907 ! NU133_HUMAN-Phosphoserine501 [Term] id: CCO:B0063022 name: APBA1_HUMAN def: "Amyloid beta A4 precursor protein-binding family A member 1" [UniProtKB:Q02410] synonym: "Adapter protein X11alpha" EXACT [UniProtKB:Q02410] synonym: "Mint-1" EXACT [UniProtKB:Q02410] synonym: "Neuron-specific X11 protein" EXACT [UniProtKB:Q02410] synonym: "Neuronal Munc18-1-interacting protein 1" EXACT [UniProtKB:Q02410] xref: EMBL:AAA61307.1 xref: EMBL:AAC05304.1 xref: EMBL:AAC39766.1 xref: EMBL:CAH74104.1 xref: EMBL:CAI15443.1 xref: UniProtKB:O14914 xref: UniProtKB:O60570 xref: UniProtKB:Q02410 xref: UniProtKB:Q5VYR8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022040 ! APBA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: participates_in CCO:I0016220 ! app-apb1-1 physical interaction relationship: participates_in CCO:I0019223 ! app-apba1-1 physical interaction relationship: participates_in CCO:I0019224 ! apba1-app-1 physical interaction [Term] id: CCO:B0063023 name: COG4_HUMAN def: "Conserved oligomeric Golgi complex subunit 4" [UniProtKB:Q9H9E3] synonym: "COG complex subunit 4" EXACT [UniProtKB:Q9H9E3] synonym: "Component of oligomeric Golgi complex 4" EXACT [UniProtKB:Q9H9E3] xref: EMBL:AAH00796.1 xref: EMBL:AAH06306.2 xref: EMBL:AAH13347.2 xref: EMBL:AAH72438.1 xref: EMBL:BAB14286.1 xref: EMBL:BAB15483.1 xref: EMBL:BAC05682.1 xref: EMBL:CAB43272.1 xref: UniProtKB:Q96D40 xref: UniProtKB:Q9BRF0 xref: UniProtKB:Q9BVZ2 xref: UniProtKB:Q9H5Y4 xref: UniProtKB:Q9H9E3 xref: UniProtKB:Q9Y3W3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022143 ! COG4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016222 ! cog4-cog7-1 physical interaction relationship: participates_in CCO:I0016223 ! cog7-cog4-1 physical interaction relationship: transforms_into CCO:B0065888 ! COG4_HUMAN-Phosphotyrosine714 [Term] id: CCO:B0063024 name: COG5_HUMAN def: "Conserved oligomeric Golgi complex subunit 5" [UniProtKB:Q9UP83] synonym: "13S Golgi transport complex 90 kDa subunit" EXACT [UniProtKB:Q9UP83] synonym: "COG complex subunit 5" EXACT [UniProtKB:Q9UP83] synonym: "Component of oligomeric Golgi complex 5" EXACT [UniProtKB:Q9UP83] synonym: "Golgi transport complex 1" EXACT [UniProtKB:Q9UP83] synonym: "GTC-90" EXACT [UniProtKB:Q9UP83] xref: EMBL:AAB63816.2 xref: EMBL:AAC69276.1 xref: EMBL:AAC83406.1 xref: EMBL:AAH68540.1 xref: EMBL:EAL24392.1 xref: EMBL:EAL24393.1 xref: EMBL:EAW83395.1 xref: EMBL:EAW83396.1 xref: UniProtKB:A4D0R6 xref: UniProtKB:A4D0R7 xref: UniProtKB:O14555 xref: UniProtKB:O95008 xref: UniProtKB:Q6NUL5 xref: UniProtKB:Q9UP83 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022144 ! COG5_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000842 ! Golgi transport complex relationship: participates_in CCO:I0016224 ! cog5-cog7-1 physical interaction relationship: participates_in CCO:I0016225 ! cog7-cog5-1 physical interaction relationship: transforms_into CCO:B0065889 ! COG5_HUMAN-Phosphoserine197 [Term] id: CCO:B0063025 name: EEA1_HUMAN def: "Early endosome antigen 1" [UniProtKB:Q15075] synonym: "Endosome-associated protein p162" EXACT [UniProtKB:Q15075] synonym: "Zinc finger FYVE domain-containing protein 2" EXACT [UniProtKB:Q15075] xref: EMBL:AAA79121.1 xref: EMBL:CAA55632.1 xref: UniProtKB:Q14221 xref: UniProtKB:Q15075 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022212 ! EEA1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000899 ! extrinsic to plasma membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: located_in CCO:C0002117 ! serine-pyruvate aminotransferase complex relationship: participates_in CCO:I0016229 ! rab5-eea1-1 physical interaction relationship: participates_in CCO:I0017985 ! eea1-rab5b-1 physical interaction relationship: participates_in CCO:I0017986 ! eea1-rab5a-1 physical interaction relationship: participates_in CCO:I0018477 ! eea1-rab22a-1 physical interaction relationship: participates_in CCO:I0018478 ! eea1-rab22a-2 physical interaction relationship: participates_in CCO:I0018593 ! eea1-rab5b-2 physical interaction relationship: participates_in CCO:I0018594 ! eea1-rab5b-3 colocalization relationship: participates_in CCO:I0018771 ! eea1-rab22a-3 physical interaction relationship: participates_in CCO:I0018772 ! eea1-rab5a-2 physical interaction [Term] id: CCO:B0063026 name: NCF2_HUMAN def: "Neutrophil cytosol factor 2" [UniProtKB:P19878] synonym: "67 kDa neutrophil oxidase factor" EXACT [UniProtKB:P19878] synonym: "NADPH oxidase activator 2" EXACT [UniProtKB:P19878] synonym: "NCF-2" EXACT [UniProtKB:P19878] synonym: "Neutrophil NADPH oxidase factor 2" EXACT [UniProtKB:P19878] synonym: "p67-phox" EXACT [UniProtKB:P19878] xref: EMBL:AAA36379.1 xref: EMBL:AAB60320.1 xref: EMBL:AAH01606.1 xref: EMBL:AAM89263.1 xref: EMBL:AAP36107.1 xref: EMBL:ABC40738.1 xref: EMBL:CAC19686.1 xref: UniProtKB:P19878 xref: UniProtKB:Q2PP06 xref: UniProtKB:Q8NFC7 xref: UniProtKB:Q9BV51 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022431 ! NCF2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000177 ! acrosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016242 ! cdc42-ncf2-1 physical interaction relationship: participates_in CCO:I0016243 ! rac1-ncf2-2 physical interaction relationship: participates_in CCO:I0016244 ! rac2-ncf2-1 physical interaction relationship: participates_in CCO:I0018171 ! rac1-ncf2-3 direct interaction [Term] id: CCO:B0063027 name: ZRAN1_HUMAN def: "Zinc finger Ran-binding domain-containing protein 1" [UniProtKB:Q9UGI0] synonym: "Protein TRABID" EXACT [UniProtKB:Q9UGI0] xref: EMBL:CAB64449.1 xref: EMBL:CAH72159.1 xref: EMBL:CAI16103.1 xref: EMBL:EAW49252.1 xref: UniProtKB:Q5SQP6 xref: UniProtKB:Q9UGI0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022828 ! ZRANB1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016266 ! traf6-trabid physical interaction [Term] id: CCO:B0063028 name: OIP5_HUMAN def: "Opa-interacting protein 5" [UniProtKB:O43482] synonym: "Cancer/testis antigen 86" EXACT [UniProtKB:O43482] synonym: "CT86" EXACT [UniProtKB:O43482] xref: EMBL:AAC39561.1 xref: EMBL:AAH15050.1 xref: UniProtKB:O43482 xref: UniProtKB:Q96BX7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022477 ! OIP5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000730 ! chromocenter relationship: located_in CCO:C0000750 ! Cajal body relationship: participates_in CCO:I0016273 ! raf1-oip5 physical interaction relationship: participates_in CCO:I0017687 ! raf1-oip5-3 physical interaction relationship: participates_in CCO:I0017760 ! raf1-oip5-2 physical interaction relationship: participates_in CCO:I0018501 ! braf-oip5 physical interaction relationship: participates_in CCO:I0019378 ! raf1-oip5-1 physical interaction [Term] id: CCO:B0063029 name: KPYM_HUMAN def: "Pyruvate kinase isozymes M1/M2" [UniProtKB:P14618] synonym: "CTHBP" EXACT [UniProtKB:P14618] synonym: "Cytosolic thyroid hormone-binding protein" EXACT [UniProtKB:P14618] synonym: "EC 2.7.1.40" EXACT [UniProtKB:P14618] synonym: "Pyruvate kinase 2/3" EXACT [UniProtKB:P14618] synonym: "Pyruvate kinase muscle isozyme" EXACT [UniProtKB:P14618] synonym: "THBP1" EXACT [UniProtKB:P14618] xref: EMBL:AAA36449.1 xref: EMBL:AAA36672.1 xref: EMBL:AAC39559.1 xref: EMBL:AAH00481.3 xref: EMBL:AAH07640.1 xref: EMBL:AAH07952.3 xref: EMBL:AAH12811.3 xref: EMBL:AAH35198.1 xref: EMBL:AAQ15274.1 xref: EMBL:BAD96647.1 xref: EMBL:CAA39849.1 xref: EMBL:EAW77884.1 xref: UniProtKB:A6NFK3 xref: UniProtKB:P14618 xref: UniProtKB:P14786 xref: UniProtKB:Q53GK4 xref: UniProtKB:Q96E76 xref: UniProtKB:Q9BWB5 xref: UniProtKB:Q9UPF2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022356 ! PKM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016274 ! raf1-pkm2 physical interaction relationship: participates_in CCO:I0017680 ! raf1-pkm2-2 physical interaction relationship: participates_in CCO:I0018809 ! araf-pkm2 physical interaction relationship: participates_in CCO:I0019371 ! raf1-pkm2-1 physical interaction relationship: transforms_into CCO:B0067432 ! KPYM_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0067433 ! KPYM_HUMAN-Phosphoserine37 relationship: transforms_into CCO:B0067434 ! KPYM_HUMAN-Phosphothreonine45 relationship: transforms_into CCO:B0067435 ! KPYM_HUMAN-Phosphotyrosine83 relationship: transforms_into CCO:B0067436 ! KPYM_HUMAN-Phosphotyrosine105 relationship: transforms_into CCO:B0067437 ! KPYM_HUMAN-Phosphotyrosine148 relationship: transforms_into CCO:B0067438 ! KPYM_HUMAN-Phosphothreonine328 relationship: transforms_into CCO:B0067439 ! KPYM_HUMAN-Phosphotyrosine390 [Term] id: CCO:B0063030 name: SFRS2_HUMAN def: "Splicing factor, arginine/serine-rich 2" [UniProtKB:Q01130] synonym: "Protein PR264" EXACT [UniProtKB:Q01130] synonym: "SC-35" EXACT [UniProtKB:Q01130] synonym: "Splicing component, 35 kDa" EXACT [UniProtKB:Q01130] synonym: "Splicing factor SC35" EXACT [UniProtKB:Q01130] xref: EMBL:AAA60162.1 xref: EMBL:AAA60306.1 xref: EMBL:AAH00339.1 xref: EMBL:AAH01303.1 xref: EMBL:AAH70086.1 xref: EMBL:AAP35914.1 xref: EMBL:CAA44307.1 xref: EMBL:CAA53383.1 xref: UniProtKB:Q01130 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022647 ! SFRS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016281 ! cir-sfrs2-1 physical interaction relationship: participates_in CCO:I0018656 ! cir-sfrs2-2 physical interaction relationship: participates_in CCO:I0018658 ! cir-sfrs2-3 physical interaction relationship: participates_in CCO:I0018831 ! sfrs2-1700023b02rik colocalization relationship: transforms_into CCO:B0070417 ! SFRS2_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0070418 ! SFRS2_HUMAN-Phosphotyrosine23 relationship: transforms_into CCO:B0070419 ! SFRS2_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0070420 ! SFRS2_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0070421 ! SFRS2_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0070422 ! SFRS2_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0070423 ! SFRS2_HUMAN-Phosphoserine204 relationship: transforms_into CCO:B0070424 ! SFRS2_HUMAN-Phosphoserine206 relationship: transforms_into CCO:B0070425 ! SFRS2_HUMAN-Phosphoserine208 relationship: transforms_into CCO:B0070426 ! SFRS2_HUMAN-Phosphoserine212 relationship: transforms_into CCO:B0070427 ! SFRS2_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0070428 ! SFRS2_HUMAN-Phosphoserine221 [Term] id: CCO:B0063031 name: U2AF1_HUMAN def: "Splicing factor U2AF 35 kDa subunit" [UniProtKB:Q01081] synonym: "U2 auxiliary factor 35 kDa subunit" EXACT [UniProtKB:Q01081] synonym: "U2 snRNP auxiliary factor small subunit" EXACT [UniProtKB:Q01081] xref: EMBL:AAA36619.1 xref: EMBL:AAH01177.1 xref: EMBL:AAH01923.1 xref: EMBL:BAA95534.1 xref: UniProtKB:Q01081 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022750 ! U2AF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016282 ! cir-u2af1-1 physical interaction relationship: participates_in CCO:I0018655 ! cir-u2af1-2 physical interaction relationship: participates_in CCO:I0018659 ! cir-u2af1-3 physical interaction relationship: participates_in CCO:I0018832 ! cir-u2af1-4 direct interaction relationship: transforms_into CCO:B0071647 ! U2AF1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0071648 ! U2AF1_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0071649 ! U2AF1_HUMAN-Phosphoserine195 relationship: transforms_into CCO:B0071650 ! U2AF1_HUMAN-Phosphoserine197 [Term] id: CCO:B0063032 name: MAGI2_HUMAN def: "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2" [UniProtKB:Q86UL8] synonym: "Atrophin-1-interacting protein 1" EXACT [UniProtKB:Q86UL8] synonym: "Atrophin-1-interacting protein A" EXACT [UniProtKB:Q86UL8] synonym: "MAGI-2" EXACT [UniProtKB:Q86UL8] synonym: "Membrane-associated guanylate kinase inverted 2" EXACT [UniProtKB:Q86UL8] xref: EMBL:AAC05370.1 xref: EMBL:AAC23438.1 xref: EMBL:AAC25530.1 xref: EMBL:AAC61488.1 xref: EMBL:AAC79151.1 xref: EMBL:AAD15413.2 xref: EMBL:AAF66080.1 xref: EMBL:AAP21886.1 xref: EMBL:AAP22360.1 xref: EMBL:BAA31680.2 xref: UniProtKB:O60434 xref: UniProtKB:O60510 xref: UniProtKB:Q86UI7 xref: UniProtKB:Q86UL8 xref: UniProtKB:Q9NP44 xref: UniProtKB:Q9UDQ5 xref: UniProtKB:Q9UDU1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022387 ! MAGI2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016327 ! magi2-adrb1-2 direct interaction relationship: participates_in CCO:I0016328 ! magi2-adrb1-1 direct interaction relationship: participates_in CCO:I0017294 ! kiaa1206-aip1 physical interaction relationship: transforms_into CCO:B0067854 ! MAGI2_HUMAN-Phosphotyrosine362 relationship: transforms_into CCO:B0067855 ! MAGI2_HUMAN-Phosphotyrosine366 relationship: transforms_into CCO:B0067856 ! MAGI2_HUMAN-Phosphotyrosine827 relationship: transforms_into CCO:B0067857 ! MAGI2_HUMAN-Phosphoserine1014 [Term] id: CCO:B0063033 name: GOPC_HUMAN def: "Golgi-associated PDZ and coiled-coil motif-containing protein" [UniProtKB:Q9HD26] synonym: "CFTR-associated ligand" EXACT [UniProtKB:Q9HD26] synonym: "Fused in glioblastoma" EXACT [UniProtKB:Q9HD26] synonym: "PDZ protein interacting specifically with TC10" EXACT [UniProtKB:Q9HD26] synonym: "PIST" EXACT [UniProtKB:Q9HD26] xref: EMBL:AAG00572.1 xref: EMBL:AAH09553.1 xref: EMBL:AAK57733.1 xref: EMBL:AAL47160.1 xref: EMBL:BAD92622.1 xref: EMBL:CAH70198.1 xref: EMBL:CAH70199.1 xref: EMBL:CAI43172.1 xref: EMBL:CAI43173.1 xref: EMBL:EAW48205.1 xref: UniProtKB:A6NM30 xref: UniProtKB:Q59FS4 xref: UniProtKB:Q969U8 xref: UniProtKB:Q9HD26 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022285 ! GOPC_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005778 ! cystic fibrosis transmembrane conductance regulator binding relationship: has_function CCO:F0007779 ! syntaxin-6 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0016329 ! gopc-adrb1-1 direct interaction relationship: participates_in CCO:I0018286 ! cftr-pist-1 physical interaction relationship: transforms_into CCO:B0066518 ! GOPC_HUMAN-Phosphotyrosine457 relationship: transforms_into CCO:B0066519 ! GOPC_HUMAN-Phosphotyrosine462 [Term] id: CCO:B0063034 name: RRAGD_HUMAN def: "Ras-related GTP-binding protein D" [UniProtKB:Q9NQL2] synonym: "Rag D" EXACT [UniProtKB:Q9NQL2] xref: EMBL:AAG32663.1 xref: EMBL:AAH03088.1 xref: EMBL:CAB70775.2 xref: EMBL:CAB99361.1 xref: EMBL:CAB99362.1 xref: UniProtKB:Q7L8F9 xref: UniProtKB:Q9NPG0 xref: UniProtKB:Q9NQL2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022607 ! RRAGD_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016331 ! rraga-rragd-3 physical interaction relationship: participates_in CCO:I0016333 ! rragb-rragd-1 physical interaction relationship: participates_in CCO:I0016335 ! rragd-rraga-4 physical interaction relationship: participates_in CCO:I0017938 ! rraga-rragd-2 physical interaction relationship: participates_in CCO:I0018099 ! rraga-rragd-1 physical interaction [Term] id: CCO:B0063035 name: C1QBP_HUMAN def: "Complement component 1 Q subcomponent-binding protein, mitochondrial precursor" [UniProtKB:Q07021] synonym: "C1qBP" EXACT [UniProtKB:Q07021] synonym: "GC1q-R protein" EXACT [UniProtKB:Q07021] synonym: "Glycoprotein gC1qBP" EXACT [UniProtKB:Q07021] synonym: "Hyaluronan-binding protein 1" EXACT [UniProtKB:Q07021] synonym: "Mitochondrial matrix protein p32" EXACT [UniProtKB:Q07021] synonym: "p33" EXACT [UniProtKB:Q07021] xref: EMBL:AAA16315.1 xref: EMBL:AAA73055.1 xref: EMBL:AAF78763.1 xref: EMBL:AAH00435.1 xref: EMBL:AAH13731.1 xref: EMBL:AAK26580.1 xref: EMBL:AAV38701.1 xref: EMBL:AAV38702.1 xref: EMBL:ABC79624.1 xref: EMBL:CAA53512.1 xref: UniProtKB:Q07021 xref: UniProtKB:Q2HXR8 xref: UniProtKB:Q9NNY8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022078 ! C1QBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016355 ! rel-c1qbp physical interaction relationship: participates_in CCO:I0016455 ! ikbkb-c1qbp physical interaction relationship: participates_in CCO:I0016693 ! map3k3-c1qbp physical interaction relationship: participates_in CCO:I0016866 ! relb-c1qbp physical interaction relationship: participates_in CCO:I0016944 ! q9nyj8-c1qbp physical interaction relationship: participates_in CCO:I0016999 ! tnfrsf1a-c1qbp physical interaction relationship: participates_in CCO:I0017066 ! tradd-c1qbp physical interaction relationship: participates_in CCO:I0017095 ! traf1-c1qbp physical interaction relationship: transforms_into CCO:B0065800 ! C1QBP_HUMAN-Phosphotyrosine188 relationship: transforms_into CCO:B0065801 ! C1QBP_HUMAN-Phosphoserine201 [Term] id: CCO:B0063036 name: WDR37_HUMAN def: "WD repeat-containing protein 37" [UniProtKB:Q9Y2I8] xref: EMBL:BAA76826.2 xref: EMBL:CAB66761.1 xref: EMBL:CAI15166.1 xref: UniProtKB:Q5SW03 xref: UniProtKB:Q9NTJ6 xref: UniProtKB:Q9Y2I8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022782 ! WDR37_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016362 ! rel-wdr37 physical interaction [Term] id: CCO:B0063037 name: Q9UQC1_HUMAN def: "Heat shock protein 72" [UniProtKB:Q9UQC1] xref: EMBL:BAA77235.1 xref: UniProtKB:Q9UQC1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022865 ! HSP70-1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016363 ! rel-hsp70_1 physical interaction relationship: participates_in CCO:I0016381 ! nfkbia-hsp70_1 physical interaction relationship: participates_in CCO:I0016405 ! nfkbib-hsp70_1 physical interaction relationship: participates_in CCO:I0016439 ! chuk-hsp70_1 physical interaction relationship: participates_in CCO:I0016461 ! ikbkb-hsp70_1 physical interaction relationship: participates_in CCO:I0016478 ! ikbke-hsp70_1 physical interaction relationship: participates_in CCO:I0016528 ! ikbkg-hsp70_1 physical interaction relationship: participates_in CCO:I0016580 ! tank-hsp70_1 physical interaction relationship: participates_in CCO:I0016629 ! map3k1-hsp70_1 physical interaction relationship: participates_in CCO:I0016721 ! map3k3-hsp70_1 physical interaction relationship: participates_in CCO:I0016809 ! nfkb2-hsp70_1-1 physical interaction relationship: participates_in CCO:I0016875 ! relb-hsp70_1 physical interaction relationship: participates_in CCO:I0016903 ! ripk1-hsp70_1 physical interaction relationship: participates_in CCO:I0016913 ! ripk2-hsp70_1 physical interaction relationship: participates_in CCO:I0016930 ! map3k7ip1-hsp70_1 physical interaction relationship: participates_in CCO:I0016952 ! q9nyj8-hsp70_1 physical interaction relationship: participates_in CCO:I0016972 ! tbk1-hsp70_1 physical interaction relationship: participates_in CCO:I0017017 ! tnfrsf1a-hsp70_1 physical interaction relationship: participates_in CCO:I0017076 ! tradd-hsp70_1 physical interaction relationship: participates_in CCO:I0017101 ! traf1-hsp70_1 physical interaction relationship: participates_in CCO:I0017127 ! traf2-hsp70_1 physical interaction relationship: participates_in CCO:I0017145 ! traf6-hsp70_1 physical interaction [Term] id: CCO:B0063038 name: UACA_HUMAN def: "Uveal autoantigen with coiled-coil domains and ankyrin repeats" [UniProtKB:Q9BZF9] xref: EMBL:AAG49577.1 xref: EMBL:AAI13408.1 xref: EMBL:AAI13410.1 xref: EMBL:BAA91457.1 xref: EMBL:BAB13387.2 xref: EMBL:CAD39123.1 xref: UniProtKB:Q14DD3 xref: UniProtKB:Q8N3B8 xref: UniProtKB:Q9BZF9 xref: UniProtKB:Q9HCL1 xref: UniProtKB:Q9NWC6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022753 ! UACA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016365 ! rel-q9bzf9 physical interaction relationship: participates_in CCO:I0016735 ! map3k3-q9bzf9 physical interaction relationship: transforms_into CCO:B0071661 ! UACA_HUMAN-Phosphotyrosine723 relationship: transforms_into CCO:B0071662 ! UACA_HUMAN-Phosphothreonine1065 [Term] id: CCO:B0063039 name: FKBP5_HUMAN def: "FK506-binding protein 5" [UniProtKB:Q13451] synonym: "51 kDa FK506-binding protein" EXACT [UniProtKB:Q13451] synonym: "54 kDa progesterone receptor-associated immunophilin" EXACT [UniProtKB:Q13451] synonym: "Androgen-regulated protein 6" EXACT [UniProtKB:Q13451] synonym: "EC 5.2.1.8" EXACT [UniProtKB:Q13451] synonym: "FF1 antigen" EXACT [UniProtKB:Q13451] synonym: "FKBP-51" EXACT [UniProtKB:Q13451] synonym: "FKBP54" EXACT [UniProtKB:Q13451] synonym: "HSP90-binding immunophilin" EXACT [UniProtKB:Q13451] synonym: "P54" EXACT [UniProtKB:Q13451] synonym: "Peptidyl-prolyl cis-trans isomerase" EXACT [UniProtKB:Q13451] synonym: "PPIase" EXACT [UniProtKB:Q13451] synonym: "Rotamase" EXACT [UniProtKB:Q13451] xref: EMBL:AAA86245.1 xref: EMBL:AAC51189.1 xref: EMBL:AAH42605.1 xref: EMBL:AAL54872.1 xref: UniProtKB:Q13451 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022255 ! FKBP5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016366 ! rel-fkbp5 physical interaction relationship: participates_in CCO:I0017205 ! chuk-fkbp5 physical interaction relationship: participates_in CCO:I0017212 ! ikbke-fkbp5 physical interaction relationship: participates_in CCO:I0017225 ! map3k1-fkbp5 physical interaction relationship: participates_in CCO:I0018585 ! fkbp5-chuk physical interaction relationship: transforms_into CCO:B0066198 ! FKBP5_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0066199 ! FKBP5_HUMAN-Phosphoserine445 [Term] id: CCO:B0063040 name: RPOM_HUMAN def: "DNA-directed RNA polymerase, mitochondrial precursor" [UniProtKB:O00411] synonym: "EC 2.7.7.6" EXACT [UniProtKB:O00411] synonym: "MtRPOL" EXACT [UniProtKB:O00411] xref: EMBL:AAB58255.1 xref: EMBL:AAC06147.1 xref: UniProtKB:O00411 xref: UniProtKB:O60370 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022606 ! POLRMT_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0016375 ! nfkbia-polrmt physical interaction relationship: participates_in CCO:I0016789 ! nfkb2-polrmt physical interaction [Term] id: CCO:B0063041 name: SPRR3_HUMAN def: "Small proline-rich protein 3" [UniProtKB:Q9UBC9] synonym: "22 kDa pancornulin" EXACT [UniProtKB:Q9UBC9] synonym: "Cornifin beta" EXACT [UniProtKB:Q9UBC9] synonym: "Esophagin" EXACT [UniProtKB:Q9UBC9] xref: EMBL:AAD11938.1 xref: EMBL:AAH17802.1 xref: EMBL:AAM74559.1 xref: EMBL:AAY26394.1 xref: EMBL:CAB65098.1 xref: EMBL:CAI19803.1 xref: UniProtKB:O75597 xref: UniProtKB:Q4ZGI7 xref: UniProtKB:Q5T525 xref: UniProtKB:Q8NET7 xref: UniProtKB:Q9UBC9 xref: UniProtKB:Q9UDG3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022671 ! SPRR3_human relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016382 ! nfkbia-sprr3 physical interaction [Term] id: CCO:B0063042 name: PTN13_HUMAN def: "Tyrosine-protein phosphatase non-receptor type 13" [UniProtKB:Q12923] synonym: "EC 3.1.3.48" EXACT [UniProtKB:Q12923] synonym: "FAP-1" EXACT [UniProtKB:Q12923] synonym: "Fas-associated protein-tyrosine phosphatase 1" EXACT [UniProtKB:Q12923] synonym: "hPTPE1" EXACT [UniProtKB:Q12923] synonym: "Protein-tyrosine phosphatase 1E" EXACT [UniProtKB:Q12923] synonym: "Protein-tyrosine phosphatase PTPL1" EXACT [UniProtKB:Q12923] synonym: "PTP-BAS" EXACT [UniProtKB:Q12923] synonym: "PTP-E1" EXACT [UniProtKB:Q12923] xref: EMBL:AAB60339.1 xref: EMBL:AAC41755.1 xref: EMBL:AAF63474.1 xref: EMBL:AAH39610.1 xref: EMBL:BAA04750.1 xref: EMBL:BAA04751.1 xref: EMBL:BAA04752.1 xref: EMBL:CAA56124.1 xref: EMBL:CAA56563.1 xref: UniProtKB:Q12923 xref: UniProtKB:Q15159 xref: UniProtKB:Q15263 xref: UniProtKB:Q15264 xref: UniProtKB:Q15265 xref: UniProtKB:Q15674 xref: UniProtKB:Q16826 xref: UniProtKB:Q8IWH7 xref: UniProtKB:Q9NYN9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022540 ! PTPN13_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: participates_in CCO:I0016385 ! nfkbia-ptpn13 physical interaction [Term] id: CCO:B0063043 name: BAG2_HUMAN def: "BAG family molecular chaperone regulator 2" [UniProtKB:O95816] synonym: "BAG-2" EXACT [UniProtKB:O95816] synonym: "Bcl-2-associated athanogene 2" EXACT [UniProtKB:O95816] xref: EMBL:AAD16121.1 xref: EMBL:AAI25040.1 xref: EMBL:CAB43388.1 xref: EMBL:CAG38527.1 xref: EMBL:CAI20515.1 xref: EMBL:CAI21565.1 xref: UniProtKB:O95816 xref: UniProtKB:Q08AS9 xref: UniProtKB:Q6FID0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022066 ! BAG2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004341 ! chaperone regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0016387 ! nfkbib-bag2 physical interaction relationship: participates_in CCO:I0016589 ! map3k1-bag2 physical interaction relationship: participates_in CCO:I0016659 ! map3k3-bag2 physical interaction relationship: participates_in CCO:I0016935 ! q9nyj8-bag2 physical interaction relationship: participates_in CCO:I0016982 ! tnfrsf1a-bag2 physical interaction relationship: participates_in CCO:I0017087 ! traf1-bag2 physical interaction relationship: participates_in CCO:I0017111 ! traf2-bag2 physical interaction [Term] id: CCO:B0063044 name: SLPI_HUMAN def: "Antileukoproteinase precursor" [UniProtKB:P03973] synonym: "ALP" EXACT [UniProtKB:P03973] synonym: "BLPI" EXACT [UniProtKB:P03973] synonym: "HUSI-1" EXACT [UniProtKB:P03973] synonym: "MPI" EXACT [UniProtKB:P03973] synonym: "Mucus proteinase inhibitor" EXACT [UniProtKB:P03973] synonym: "Protease inhibitor WAP4" EXACT [UniProtKB:P03973] synonym: "Secretory leukocyte protease inhibitor" EXACT [UniProtKB:P03973] synonym: "Seminal proteinase inhibitor" EXACT [UniProtKB:P03973] synonym: "WAP four-disulfide core domain protein 4" EXACT [UniProtKB:P03973] xref: EMBL:AAD19661.1 xref: EMBL:AAH20708.1 xref: EMBL:CAA28158.1 xref: EMBL:CAA28187.1 xref: EMBL:CAA28188.1 xref: EMBL:CAB64235.1 xref: UniProtKB:P03973 xref: UniProtKB:P07757 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022656 ! SLPI_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0004441 ! protease inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0016393 ! nfkbib-slpi physical interaction [Term] id: CCO:B0063045 name: SYIC_HUMAN def: "Isoleucyl-tRNA synthetase, cytoplasmic" [UniProtKB:P41252] synonym: "EC 6.1.1.5" EXACT [UniProtKB:P41252] synonym: "IleRS" EXACT [UniProtKB:P41252] synonym: "IRS" EXACT [UniProtKB:P41252] synonym: "Isoleucine--tRNA ligase" EXACT [UniProtKB:P41252] xref: EMBL:AAA80153.1 xref: EMBL:BAA05835.1 xref: EMBL:CAI16202.2 xref: UniProtKB:P41252 xref: UniProtKB:Q5TCD0 xref: UniProtKB:Q9H588 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022691 ! IARS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001180 ! isoleucine-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016395 ! nfkbib-iars physical interaction relationship: participates_in CCO:I0016513 ! ikbkg-iars physical interaction relationship: participates_in CCO:I0016575 ! tank-iars physical interaction relationship: participates_in CCO:I0016690 ! map3k3-iars physical interaction relationship: participates_in CCO:I0016791 ! nfkb2-iars-1 physical interaction relationship: transforms_into CCO:B0071040 ! SYIC_HUMAN-Phosphoserine1051 [Term] id: CCO:B0063046 name: SYEP_HUMAN def: "Bifunctional aminoacyl-tRNA synthetase" [UniProtKB:P07814] synonym: "Proliferation-inducing gene 32 protein" EXACT [UniProtKB:P07814] xref: EMBL:AAH15494.1 xref: EMBL:AAH34797.1 xref: EMBL:AAH46156.1 xref: EMBL:AAH58921.1 xref: EMBL:AAI26276.1 xref: EMBL:AAS72877.1 xref: EMBL:CAA30354.1 xref: EMBL:CAA38224.1 xref: EMBL:CAI45949.1 xref: UniProtKB:A0AVA9 xref: UniProtKB:P07814 xref: UniProtKB:Q05BP6 xref: UniProtKB:Q05DF8 xref: UniProtKB:Q5DSM1 xref: UniProtKB:Q5H9S5 xref: UniProtKB:Q6PD57 xref: UniProtKB:Q86X73 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022689 ! EPRS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016396 ! nfkbib-eprs physical interaction relationship: participates_in CCO:I0016454 ! ikbkb-eprs physical interaction relationship: participates_in CCO:I0016793 ! nfkb2-eprs physical interaction relationship: participates_in CCO:I0016865 ! relb-eprs physical interaction relationship: participates_in CCO:I0019896 ! arf4l-eprs physical interaction relationship: participates_in CCO:I0020478 ! th1l-eprs physical interaction relationship: transforms_into CCO:B0071033 ! SYEP_HUMAN-Phosphoserine885 relationship: transforms_into CCO:B0071034 ! SYEP_HUMAN-Phosphoserine886 relationship: transforms_into CCO:B0071035 ! SYEP_HUMAN-Phosphothreonine888 relationship: transforms_into CCO:B0071036 ! SYEP_HUMAN-Phosphoserine891 relationship: transforms_into CCO:B0071037 ! SYEP_HUMAN-Phosphothreonine898 relationship: transforms_into CCO:B0071038 ! SYEP_HUMAN-Phosphoserine1000 [Term] id: CCO:B0063047 name: LYSC_HUMAN def: "Lysozyme C precursor" [UniProtKB:P61626] synonym: "1,4-beta-N-acetylmuramidase C" EXACT [UniProtKB:P61626] synonym: "EC 3.2.1.17" EXACT [UniProtKB:P61626] xref: EMBL:AAA36188.1 xref: EMBL:AAA59535.1 xref: EMBL:AAA59536.1 xref: EMBL:AAC63078.1 xref: EMBL:AAH04147.1 xref: EMBL:CAA32175.1 xref: UniProtKB:P00695 xref: UniProtKB:P61626 xref: UniProtKB:Q13170 xref: UniProtKB:Q9UCF8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022382 ! LYZ_human relationship: has_function CCO:F0000326 ! lysozyme activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0016398 ! nfkbib-lyz physical interaction relationship: participates_in CCO:I0016457 ! ikbkb-lyz physical interaction [Term] id: CCO:B0063048 name: RL35A_HUMAN def: "60S ribosomal protein L35a" [UniProtKB:P18077] synonym: "Cell growth-inhibiting gene 33 protein" EXACT [UniProtKB:P18077] xref: EMBL:AAH01037.1 xref: EMBL:AAH10949.1 xref: EMBL:AAH17093.1 xref: EMBL:AAH61890.1 xref: EMBL:AAX11429.1 xref: EMBL:CAA37138.1 xref: EMBL:CAA64325.1 xref: EMBL:EAW92249.1 xref: UniProtKB:P18077 xref: UniProtKB:Q08ES9 xref: UniProtKB:Q9BVN7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022577 ! RPL35A_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016403 ! nfkbib-rpl35a physical interaction relationship: participates_in CCO:I0016626 ! map3k1-rpl35a physical interaction relationship: participates_in CCO:I0020152 ! rpl35a-sh3gl3 physical interaction [Term] id: CCO:B0063049 name: EXOC4_HUMAN def: "Exocyst complex component 4" [UniProtKB:Q96A65] synonym: "Exocyst complex component Sec8" EXACT [UniProtKB:Q96A65] xref: EMBL:AAF66445.1 xref: EMBL:AAK57456.1 xref: EMBL:BAB14225.1 xref: EMBL:BAB21790.1 xref: EMBL:BAB55298.1 xref: EMBL:CAD39134.1 xref: UniProtKB:Q96A65 xref: UniProtKB:Q9C0G4 xref: UniProtKB:Q9H9K0 xref: UniProtKB:Q9P102 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022230 ! EXOC4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0016406 ! nfkbib-sec8l1 physical interaction relationship: transforms_into CCO:B0066032 ! EXOC4_HUMAN-Phosphothreonine237 [Term] id: CCO:B0063050 name: RLA0L_HUMAN def: "60S acidic ribosomal protein P0-like" [UniProtKB:Q8NHW5] xref: EMBL:AAL62450.1 xref: EMBL:EAX00373.1 xref: UniProtKB:Q8NHW5 is_a: CCO:U0000007 ! cell cycle protein relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0016410 ! nfkbib-q8nhw5 physical interaction relationship: participates_in CCO:I0016541 ! ikbkg-q8nhw5 physical interaction relationship: participates_in CCO:I0016634 ! map3k1-q8nhw5 physical interaction relationship: participates_in CCO:I0016815 ! nfkb2-q8nhw5 physical interaction relationship: participates_in CCO:I0016880 ! relb-q8nhw5 physical interaction relationship: participates_in CCO:I0016974 ! tbk1-q8nhw5 physical interaction [Term] id: CCO:B0063051 name: HNRPU_HUMAN def: "Heterogeneous nuclear ribonucleoprotein U" [UniProtKB:Q00839] synonym: "hnRNP U" EXACT [UniProtKB:Q00839] synonym: "p120" EXACT [UniProtKB:Q00839] synonym: "pp120" EXACT [UniProtKB:Q00839] synonym: "SAF-A" EXACT [UniProtKB:Q00839] synonym: "Scaffold attachment factor A" EXACT [UniProtKB:Q00839] xref: EMBL:AAC19382.1 xref: EMBL:AAH03367.1 xref: EMBL:AAH03621.1 xref: EMBL:AAH07950.2 xref: EMBL:AAH24767.1 xref: EMBL:AAH34925.1 xref: EMBL:CAA46472.1 xref: EMBL:CAI11058.1 xref: UniProtKB:O75507 xref: UniProtKB:Q00839 xref: UniProtKB:Q8N174 xref: UniProtKB:Q96HY9 xref: UniProtKB:Q9BQ09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022312 ! HNRNPU_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0016414 ! nfkbib-hnrpu physical interaction relationship: participates_in CCO:I0016463 ! ikbkb-hnrpu physical interaction relationship: participates_in CCO:I0016549 ! ikbkg-hnrpu physical interaction relationship: participates_in CCO:I0016582 ! tank-hnrpu physical interaction relationship: participates_in CCO:I0016817 ! nfkb2-hnrpu physical interaction relationship: participates_in CCO:I0016882 ! relb-hnrpu physical interaction relationship: transforms_into CCO:B0066878 ! HNRPU_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066879 ! HNRPU_HUMAN-Phosphoserine4 relationship: transforms_into CCO:B0066880 ! HNRPU_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0066881 ! HNRPU_HUMAN-Omega-N-methylarginine50 relationship: transforms_into CCO:B0066882 ! HNRPU_HUMAN-Phosphoserine59 relationship: transforms_into CCO:B0066883 ! HNRPU_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0066884 ! HNRPU_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0066885 ! HNRPU_HUMAN-Phosphoserine270 relationship: transforms_into CCO:B0066886 ! HNRPU_HUMAN-Phosphotyrosine472 relationship: transforms_into CCO:B0066887 ! HNRPU_HUMAN-Omega-N-methylated arginine732 relationship: transforms_into CCO:B0066888 ! HNRPU_HUMAN-Omega-N-methylated arginine738 [Term] id: CCO:B0063052 name: CC28A_HUMAN def: "Coiled-coil domain-containing protein 28A" [UniProtKB:Q8IWP9] synonym: "CCRL1AP" EXACT [UniProtKB:Q8IWP9] xref: EMBL:AAH13019.1 xref: EMBL:AAH80566.1 xref: EMBL:AAI08718.1 xref: EMBL:AAN87344.1 xref: EMBL:CAB43315.1 xref: EMBL:CAI42866.1 xref: UniProtKB:Q32NC7 xref: UniProtKB:Q66K67 xref: UniProtKB:Q8IWP9 xref: UniProtKB:Q96E23 xref: UniProtKB:Q9Y430 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022100 ! CCDC28A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016417 ! nfkbib-q8iwp9 physical interaction relationship: transforms_into CCO:B0065838 ! CC28A_HUMAN-Phosphotyrosine26 [Term] id: CCO:B0063053 name: ARHG2_HUMAN def: "Rho guanine nucleotide exchange factor 2" [UniProtKB:Q92974] synonym: "GEF-H1" EXACT [UniProtKB:Q92974] synonym: "Guanine nucleotide exchange factor H1" EXACT [UniProtKB:Q92974] synonym: "Microtubule-regulated Rho-GEF" EXACT [UniProtKB:Q92974] synonym: "Proliferating cell nucleolar antigen p40" EXACT [UniProtKB:Q92974] xref: EMBL:AAC97383.1 xref: EMBL:AAH20567.1 xref: EMBL:AAL96658.1 xref: EMBL:AAP36075.1 xref: EMBL:BAA31626.3 xref: EMBL:CAA33634.1 xref: EMBL:CAC21656.1 xref: EMBL:CAH72627.1 xref: EMBL:CAH72629.1 xref: EMBL:CAH72630.1 xref: EMBL:EAW53013.1 xref: EMBL:EAW53015.1 xref: UniProtKB:O75142 xref: UniProtKB:Q15079 xref: UniProtKB:Q5VY92 xref: UniProtKB:Q8TDA3 xref: UniProtKB:Q8WUG4 xref: UniProtKB:Q92974 xref: UniProtKB:Q9H023 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0021148 ! ARHGEF2_human relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003531 ! Rho GTPase binding relationship: has_function CCO:F0004518 ! Rac guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007332 ! Rac GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000434 ! microtubule relationship: participates_in CCO:I0016428 ! nfkbie-arhgef2 physical interaction relationship: transforms_into CCO:B0065712 ! ARHG2_HUMAN-Phosphoserine143 relationship: transforms_into CCO:B0065713 ! ARHG2_HUMAN-Phosphoserine149 relationship: transforms_into CCO:B0065714 ! ARHG2_HUMAN-Phosphothreonine152 relationship: transforms_into CCO:B0065715 ! ARHG2_HUMAN-Phosphothreonine153 relationship: transforms_into CCO:B0065716 ! ARHG2_HUMAN-Phosphoserine163 relationship: transforms_into CCO:B0065717 ! ARHG2_HUMAN-Phosphoserine645 relationship: transforms_into CCO:B0065718 ! ARHG2_HUMAN-Phosphoserine648 relationship: transforms_into CCO:B0065719 ! ARHG2_HUMAN-Phosphothreonine679 relationship: transforms_into CCO:B0065720 ! ARHG2_HUMAN-Phosphoserine696 relationship: transforms_into CCO:B0065721 ! ARHG2_HUMAN-Phosphoserine886 relationship: transforms_into CCO:B0065722 ! ARHG2_HUMAN-Phosphotyrosine894 relationship: transforms_into CCO:B0065723 ! ARHG2_HUMAN-Phosphoserine896 relationship: transforms_into CCO:B0065724 ! ARHG2_HUMAN-Phosphoserine932 relationship: transforms_into CCO:B0065725 ! ARHG2_HUMAN-Phosphoserine940 relationship: transforms_into CCO:B0065726 ! ARHG2_HUMAN-Phosphoserine941 relationship: transforms_into CCO:B0065727 ! ARHG2_HUMAN-Phosphoserine956 relationship: transforms_into CCO:B0065728 ! ARHG2_HUMAN-Phosphoserine960 [Term] id: CCO:B0063054 name: TPM3_HUMAN def: "Tropomyosin alpha-3 chain" [UniProtKB:P06753] synonym: "Gamma-tropomyosin" EXACT [UniProtKB:P06753] synonym: "hTM5" EXACT [UniProtKB:P06753] synonym: "Tropomyosin-3" EXACT [UniProtKB:P06753] synonym: "Tropomyosin-5" EXACT [UniProtKB:P06753] xref: EMBL:AAF87083.1 xref: EMBL:AAH00771.1 xref: EMBL:AAH08407.1 xref: EMBL:AAH08425.1 xref: EMBL:AAH15403.1 xref: EMBL:AAH72428.1 xref: EMBL:CAA27243.1 xref: EMBL:CAA27798.1 xref: EMBL:CAB37185.1 xref: EMBL:CAH71264.1 xref: UniProtKB:P06753 xref: UniProtKB:P12324 xref: UniProtKB:Q969Q2 xref: UniProtKB:Q9NQH8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022730 ! TPM3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016442 ! chuk-tpm3 physical interaction relationship: participates_in CCO:I0016483 ! ikbke-tpm3 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0071481 ! TPM3_HUMAN-Phosphotyrosine162 relationship: transforms_into CCO:B0071482 ! TPM3_HUMAN-Phosphothreonine252 relationship: transforms_into CCO:B0071483 ! TPM3_HUMAN-Phosphoserine283 [Term] id: CCO:B0063055 name: MYO1D_HUMAN def: "Myosin-Id" [UniProtKB:O94832] xref: EMBL:AAH30602.1 xref: EMBL:BAA34447.2 xref: UniProtKB:O94832 xref: UniProtKB:Q8NHP9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022421 ! MYO1D_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000788 ! myosin complex relationship: participates_in CCO:I0016446 ! chuk-myo1d physical interaction relationship: participates_in CCO:I0016568 ! ikbkg-myo1d physical interaction relationship: participates_in CCO:I0016657 ! map3k1-myo1d physical interaction relationship: participates_in CCO:I0016772 ! map3k3-myo1d physical interaction relationship: participates_in CCO:I0016920 ! ripk2-myo1d physical interaction relationship: transforms_into CCO:B0068397 ! MYO1D_HUMAN-Phosphotyrosine536 [Term] id: CCO:B0063056 name: TFR1_HUMAN def: "Transferrin receptor protein 1" [UniProtKB:P02786] synonym: "CD71 antigen" EXACT [UniProtKB:P02786] synonym: "p90" EXACT [UniProtKB:P02786] synonym: "T9" EXACT [UniProtKB:P02786] synonym: "TfR" EXACT [UniProtKB:P02786] synonym: "TfR1" EXACT [UniProtKB:P02786] synonym: "TR" EXACT [UniProtKB:P02786] synonym: "Trfr" EXACT [UniProtKB:P02786] xref: EMBL:AAA61153.1 xref: EMBL:AAF04564.1 xref: EMBL:AAH01188.1 xref: EMBL:BAD92491.1 xref: EMBL:CAA25527.1 xref: UniProtKB:P02786 xref: UniProtKB:Q59G55 xref: UniProtKB:Q9UCN0 xref: UniProtKB:Q9UCU5 xref: UniProtKB:Q9UDF9 xref: UniProtKB:Q9UK21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022708 ! TFRC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016473 ! ikbke-tfrc physical interaction relationship: participates_in CCO:I0017410 ! tfrc-tf physical interaction relationship: transforms_into CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: transforms_into CCO:B0071375 ! TFR1_HUMAN-Phosphoserine24 [Term] id: CCO:B0063057 name: SYVC_HUMAN def: "Valyl-tRNA synthetase" [UniProtKB:P26640] synonym: "EC 6.1.1.9" EXACT [UniProtKB:P26640] synonym: "Protein G7a" EXACT [UniProtKB:P26640] synonym: "Valine--tRNA ligase" EXACT [UniProtKB:P26640] synonym: "ValRS" EXACT [UniProtKB:P26640] xref: EMBL:AAA81332.1 xref: EMBL:AAD21819.1 xref: EMBL:AAH12808.1 xref: EMBL:BAB63303.1 xref: EMBL:CAA41990.1 xref: EMBL:CAI17732.1 xref: EMBL:CAI18211.1 xref: EMBL:CAI18384.1 xref: UniProtKB:P26640 xref: UniProtKB:Q5JQ90 xref: UniProtKB:Q96E77 xref: UniProtKB:Q9UQM2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022697 ! VARS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001190 ! valine-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0016487 ! ikbkg-vars2 physical interaction relationship: transforms_into CCO:B0071063 ! SYVC_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0071064 ! SYVC_HUMAN-Phosphotyrosine300 [Term] id: CCO:B0063058 name: SYRC_HUMAN def: "Arginyl-tRNA synthetase, cytoplasmic" [UniProtKB:P54136] synonym: "Arginine--tRNA ligase" EXACT [UniProtKB:P54136] synonym: "ArgRS" EXACT [UniProtKB:P54136] synonym: "EC 6.1.1.19" EXACT [UniProtKB:P54136] xref: EMBL:AAB35627.1 xref: EMBL:AAH00528.1 xref: EMBL:AAH14619.1 xref: EMBL:AAP36058.1 xref: UniProtKB:P54136 xref: UniProtKB:Q9BWA1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022696 ! RARS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001172 ! arginine-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016494 ! ikbkg-rars physical interaction relationship: participates_in CCO:I0016573 ! tank-rars physical interaction relationship: participates_in CCO:I0016779 ! nfkb2-rars physical interaction relationship: participates_in CCO:I0016988 ! tnfrsf1a-rars physical interaction [Term] id: CCO:B0063059 name: ATPO_HUMAN def: "ATP synthase subunit O, mitochondrial precursor" [UniProtKB:P48047] synonym: "Oligomycin sensitivity conferral protein" EXACT [UniProtKB:P48047] synonym: "OSCP" EXACT [UniProtKB:P48047] xref: EMBL:AAH21233.1 xref: EMBL:AAH22865.1 xref: EMBL:AAV38639.1 xref: EMBL:BAD96682.1 xref: EMBL:CAA58219.1 xref: EMBL:CAG33103.1 xref: UniProtKB:P48047 xref: UniProtKB:Q5U042 xref: UniProtKB:Q6IBI2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022061 ! ATP5O_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016497 ! ikbkg-atp5o physical interaction relationship: transforms_into CCO:B0065759 ! ATPO_HUMAN-N6-acetyllysine60 relationship: transforms_into CCO:B0065760 ! ATPO_HUMAN-N6-acetyllysine70 relationship: transforms_into CCO:B0065761 ! ATPO_HUMAN-N6-acetyllysine158 relationship: transforms_into CCO:B0065762 ! ATPO_HUMAN-N6-acetyllysine162 relationship: transforms_into CCO:B0065763 ! ATPO_HUMAN-N6-acetyllysine172 relationship: transforms_into CCO:B0065764 ! ATPO_HUMAN-N6-acetyllysine176 relationship: transforms_into CCO:B0065765 ! ATPO_HUMAN-N6-acetyllysine192 [Term] id: CCO:B0063060 name: SYMC_HUMAN def: "Methionyl-tRNA synthetase, cytoplasmic" [UniProtKB:P56192] synonym: "EC 6.1.1.10" EXACT [UniProtKB:P56192] synonym: "Methionine--tRNA ligase" EXACT [UniProtKB:P56192] synonym: "MetRS" EXACT [UniProtKB:P56192] xref: EMBL:AAH02384.1 xref: EMBL:AAH06328.1 xref: EMBL:AAH11639.1 xref: EMBL:AAH11849.1 xref: EMBL:AAH15011.1 xref: EMBL:AAP36002.1 xref: EMBL:BAA95668.1 xref: EMBL:BAD96487.1 xref: EMBL:CAA64381.1 xref: EMBL:CAA89153.1 xref: UniProtKB:P56192 xref: UniProtKB:Q14895 xref: UniProtKB:Q53H14 xref: UniProtKB:Q96A15 xref: UniProtKB:Q96BZ0 xref: UniProtKB:Q9NSE0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022693 ! MARS_human relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001183 ! methionine-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016499 ! ikbkg-mars physical interaction relationship: participates_in CCO:I0016599 ! map3k1-mars physical interaction relationship: participates_in CCO:I0016678 ! map3k3-mars physical interaction relationship: participates_in CCO:I0016782 ! nfkb2-mars physical interaction [Term] id: CCO:B0063061 name: RS5_HUMAN def: "40S ribosomal protein S5" [UniProtKB:P46782] xref: EMBL:AAA85658.1 xref: EMBL:AAH15405.1 xref: EMBL:AAH18151.1 xref: EMBL:BAA25815.1 xref: EMBL:BAB79493.1 xref: UniProtKB:P46782 xref: UniProtKB:Q96BN0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022615 ! RPS5_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016500 ! ikbkg-rps5 physical interaction relationship: participates_in CCO:I0016783 ! nfkb2-rps5 physical interaction relationship: participates_in CCO:I0016859 ! relb-rps5 physical interaction relationship: participates_in CCO:I0016962 ! tbk1-rps5 physical interaction relationship: transforms_into CCO:B0070213 ! RS5_HUMAN-N-acetylthreonine2 [Term] id: CCO:B0063062 name: SFXN1_HUMAN def: "Sideroflexin-1" [UniProtKB:Q9H9B4] synonym: "TCC" EXACT [UniProtKB:Q9H9B4] synonym: "Tricarboxylate carrier protein" EXACT [UniProtKB:Q9H9B4] xref: EMBL:AAH20517.1 xref: EMBL:AAH63241.1 xref: EMBL:AAL56007.1 xref: EMBL:BAB14003.1 xref: EMBL:BAB14318.1 xref: UniProtKB:Q9H9B4 xref: UniProtKB:Q9HA53 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022649 ! SFXN1_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001835 ! cation transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:I0016503 ! ikbkg-sfxn1 physical interaction relationship: transforms_into CCO:B0070449 ! SFXN1_HUMAN-N-acetylserine2 [Term] id: CCO:B0063063 name: MYO1C_HUMAN def: "Myosin-Ic" [UniProtKB:O00159] synonym: "MMI-beta" EXACT [UniProtKB:O00159] synonym: "MMIb" EXACT [UniProtKB:O00159] synonym: "Myosin I beta" EXACT [UniProtKB:O00159] xref: EMBL:AAH44891.2 xref: EMBL:AAH68013.1 xref: EMBL:BAF85599.1 xref: EMBL:CAA67131.1 xref: UniProtKB:O00159 xref: UniProtKB:Q6NVJ7 xref: UniProtKB:Q86Y95 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022420 ! MYO1C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000783 ! lateral plasma membrane relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0000790 ! unconventional myosin complex relationship: located_in CCO:C0001356 ! filamentous actin relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016506 ! ikbkg-myo1c physical interaction relationship: participates_in CCO:I0016683 ! map3k3-myo1c physical interaction relationship: transforms_into CCO:B0068393 ! MYO1C_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0068394 ! MYO1C_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0068395 ! MYO1C_HUMAN-N6-methyllysine348 relationship: transforms_into CCO:B0068396 ! MYO1C_HUMAN-Phosphoserine373 [Term] id: CCO:B0063064 name: TBA4B_HUMAN def: "Putative tubulin-like protein alpha-4B" [UniProtKB:Q9H853] synonym: "Alpha-tubulin 4B" EXACT [UniProtKB:Q9H853] xref: EMBL:BAB14767.1 xref: UniProtKB:Q9H853 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022702 ! TUBA4B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0016516 ! ikbkg-q9h853 physical interaction [Term] id: CCO:B0063065 name: Q9BZT1_HUMAN def: "PNAS-101" [UniProtKB:Q9BZT1] xref: EMBL:AAK07533.1 xref: UniProtKB:Q9BZT1 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016518 ! ikbkg-q9bzt1 physical interaction [Term] id: CCO:B0063066 name: PYR1_HUMAN def: "CAD protein" [UniProtKB:P27708] xref: EMBL:AAA51907.1 xref: EMBL:AAH65510.1 xref: EMBL:BAA11423.1 xref: UniProtKB:P27708 xref: UniProtKB:Q6P0Q0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022547 ! CAD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016519 ! ikbkg-cad physical interaction relationship: participates_in CCO:I0016612 ! map3k1-cad physical interaction relationship: participates_in CCO:I0016703 ! map3k3-cad physical interaction relationship: participates_in CCO:I0016799 ! nfkb2-cad-1 physical interaction relationship: participates_in CCO:I0016869 ! relb-cad physical interaction relationship: participates_in CCO:I0016900 ! ripk1-cad physical interaction relationship: participates_in CCO:I0016947 ! q9nyj8-cad physical interaction relationship: participates_in CCO:I0017005 ! tnfrsf1a-cad physical interaction relationship: participates_in CCO:I0017069 ! tradd-cad physical interaction relationship: participates_in CCO:I0017122 ! traf2-cad physical interaction relationship: transforms_into CCO:B0069649 ! PYR1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0069650 ! PYR1_HUMAN-Phosphoserine1423 relationship: transforms_into CCO:B0069651 ! PYR1_HUMAN-Phosphoserine1823 relationship: transforms_into CCO:B0069652 ! PYR1_HUMAN-Phosphoserine1859 [Term] id: CCO:B0063067 name: CALX_HUMAN def: "Calnexin precursor" [UniProtKB:P27824] synonym: "IP90" EXACT [UniProtKB:P27824] synonym: "Major histocompatibility complex class I antigen-binding protein p88" EXACT [UniProtKB:P27824] synonym: "p90" EXACT [UniProtKB:P27824] xref: EMBL:AAA21013.1 xref: EMBL:AAA21749.1 xref: EMBL:AAA35696.1 xref: EMBL:AAA36125.1 xref: EMBL:AAH03552.1 xref: EMBL:AAH42843.1 xref: EMBL:CAB72137.1 xref: UniProtKB:P27824 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022085 ! CANX_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0016520 ! ikbkg-canx physical interaction relationship: participates_in CCO:I0017006 ! tnfrsf1a-canx physical interaction relationship: transforms_into CCO:B0065813 ! CALX_HUMAN-Phosphoserine554 relationship: transforms_into CCO:B0065814 ! CALX_HUMAN-Phosphothreonine562 relationship: transforms_into CCO:B0065815 ! CALX_HUMAN-Phosphoserine564 relationship: transforms_into CCO:B0065816 ! CALX_HUMAN-Phosphoserine583 [Term] id: CCO:B0063068 name: ESYT1_HUMAN def: "Extended synaptotagmin-1" [UniProtKB:Q9BSJ8] synonym: "E-Syt1" EXACT [UniProtKB:Q9BSJ8] synonym: "Membrane-bound C2 domain-containing protein" EXACT [UniProtKB:Q9BSJ8] synonym: "Protein FAM62A" EXACT [UniProtKB:Q9BSJ8] xref: EMBL:AAH04998.1 xref: EMBL:ABJ97705.1 xref: EMBL:BAA34467.1 xref: EMBL:BAB15139.1 xref: EMBL:BAB15268.1 xref: EMBL:BAF83026.1 xref: EMBL:CAB43284.1 xref: EMBL:EAW96891.1 xref: UniProtKB:A0FGR7 xref: UniProtKB:A8K2S2 xref: UniProtKB:O94848 xref: UniProtKB:Q6PJN4 xref: UniProtKB:Q9BSJ8 xref: UniProtKB:Q9H6J1 xref: UniProtKB:Q9H6W2 xref: UniProtKB:Q9Y416 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022228 ! FAM62A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016522 ! ikbkg-q9bsj8 physical interaction relationship: transforms_into CCO:B0066026 ! ESYT1_HUMAN-Phosphotyrosine822 relationship: transforms_into CCO:B0066027 ! ESYT1_HUMAN-Phosphoserine963 relationship: transforms_into CCO:B0066028 ! ESYT1_HUMAN-Phosphotyrosine1009 relationship: transforms_into CCO:B0066029 ! ESYT1_HUMAN-Phosphoserine1034 [Term] id: CCO:B0063069 name: FA7_HUMAN def: "Coagulation factor VII precursor" [UniProtKB:P08709] synonym: "EC 3.4.21.21" EXACT [UniProtKB:P08709] synonym: "Eptacog alfa" EXACT [UniProtKB:P08709] synonym: "Proconvertin" EXACT [UniProtKB:P08709] synonym: "Serum prothrombin conversion accelerator" EXACT [UniProtKB:P08709] synonym: "SPCA" EXACT [UniProtKB:P08709] xref: EMBL:AAA51983.1 xref: EMBL:AAA88040.1 xref: EMBL:AAA88041.1 xref: EMBL:AAL66184.1 xref: EMBL:AAP33841.1 xref: EMBL:ABD17891.1 xref: EMBL:CAI41381.1 xref: UniProtKB:P08709 xref: UniProtKB:Q14339 xref: UniProtKB:Q5JVF2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022248 ! F7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016526 ! ikbkg-f7 physical interaction relationship: transforms_into CCO:B0066103 ! FA7_HUMAN-4-carboxyglutamate66 relationship: transforms_into CCO:B0066104 ! FA7_HUMAN-4-carboxyglutamate67 relationship: transforms_into CCO:B0066105 ! FA7_HUMAN-4-carboxyglutamate74 relationship: transforms_into CCO:B0066106 ! FA7_HUMAN-4-carboxyglutamate76 relationship: transforms_into CCO:B0066107 ! FA7_HUMAN-4-carboxyglutamate79 relationship: transforms_into CCO:B0066108 ! FA7_HUMAN-4-carboxyglutamate80 relationship: transforms_into CCO:B0066109 ! FA7_HUMAN-4-carboxyglutamate85 relationship: transforms_into CCO:B0066110 ! FA7_HUMAN-4-carboxyglutamate86 relationship: transforms_into CCO:B0066111 ! FA7_HUMAN-4-carboxyglutamate89 relationship: transforms_into CCO:B0066112 ! FA7_HUMAN-4-carboxyglutamate95 relationship: transforms_into CCO:B0066113 ! FA7_HUMAN-3-hydroxyaspartate123 [Term] id: CCO:B0063070 name: IDH3A_HUMAN def: "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor" [UniProtKB:P50213] synonym: "EC 1.1.1.41" EXACT [UniProtKB:P50213] synonym: "Isocitric dehydrogenase" EXACT [UniProtKB:P50213] synonym: "NAD(+)-specific ICDH" EXACT [UniProtKB:P50213] xref: EMBL:AAA85639.1 xref: EMBL:AAH21967.1 xref: EMBL:CAC09449.1 xref: UniProtKB:P50213 xref: UniProtKB:Q9H3X0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022329 ! IDH3A_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000849 ! isocitrate dehydrogenase (NAD+) activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0016527 ! ikbkg-idh3a physical interaction [Term] id: CCO:B0063071 name: Q96RI3_HUMAN def: "Short heat shock protein 60 Hsp60s2" [UniProtKB:Q96RI3] xref: EMBL:AAK60261.1 xref: UniProtKB:Q96RI3 is_a: CCO:U0000007 ! cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016532 ! ikbkg-q96ri3 physical interaction [Term] id: CCO:B0063072 name: SYLC_HUMAN def: "Leucyl-tRNA synthetase, cytoplasmic" [UniProtKB:Q9P2J5] synonym: "EC 6.1.1.4" EXACT [UniProtKB:Q9P2J5] synonym: "Leucine--tRNA ligase" EXACT [UniProtKB:Q9P2J5] synonym: "LeuRS" EXACT [UniProtKB:Q9P2J5] xref: EMBL:BAA92590.1 xref: EMBL:BAA95667.1 xref: UniProtKB:Q9NSE1 xref: UniProtKB:Q9P2J5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022692 ! LARS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016536 ! ikbkg-kiaa1352 physical interaction relationship: participates_in CCO:I0016581 ! tank-kiaa1352 physical interaction relationship: transforms_into CCO:B0071041 ! SYLC_HUMAN-Phosphoserine718 relationship: transforms_into CCO:B0071042 ! SYLC_HUMAN-Phosphothreonine721 relationship: transforms_into CCO:B0071043 ! SYLC_HUMAN-Phosphothreonine728 [Term] id: CCO:B0063073 name: USO1_HUMAN def: "General vesicular transport factor p115" [UniProtKB:O60763] synonym: "Protein USO1 homolog" EXACT [UniProtKB:O60763] synonym: "TAP" EXACT [UniProtKB:O60763] synonym: "Transcytosis-associated protein" EXACT [UniProtKB:O60763] synonym: "Vesicle-docking protein" EXACT [UniProtKB:O60763] xref: EMBL:AAH06398.1 xref: EMBL:AAH32654.1 xref: EMBL:BAA25300.1 xref: UniProtKB:O60763 xref: UniProtKB:Q6PK63 xref: UniProtKB:Q8N592 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022767 ! USO1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016542 ! ikbkg-vdp physical interaction relationship: transforms_into CCO:B0071755 ! USO1_HUMAN-Phosphoserine942 [Term] id: CCO:B0063074 name: UBP18_HUMAN def: "Ubl carboxyl-terminal hydrolase 18" [UniProtKB:Q9UMW8] synonym: "43 kDa ISG15-specific protease" EXACT [UniProtKB:Q9UMW8] synonym: "EC 3.1.2.-" EXACT [UniProtKB:Q9UMW8] synonym: "hUBP43" EXACT [UniProtKB:Q9UMW8] synonym: "ISG15-specific-processing protease" EXACT [UniProtKB:Q9UMW8] synonym: "Ubl thioesterase 18" EXACT [UniProtKB:Q9UMW8] xref: EMBL:AAD49967.1 xref: EMBL:AAH14896.1 xref: EMBL:CAB66625.1 xref: EMBL:CAB76398.1 xref: UniProtKB:Q9NY71 xref: UniProtKB:Q9UMW8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022760 ! USP18_human relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0016546 ! ikbkg-usp18 physical interaction [Term] id: CCO:B0063075 name: ADT3_HUMAN def: "ADP/ATP translocase 3" [UniProtKB:P12236] synonym: "Adenine nucleotide translocator 2" EXACT [UniProtKB:P12236] synonym: "ADP,ATP carrier protein 3" EXACT [UniProtKB:P12236] synonym: "ADP,ATP carrier protein, isoform T2" EXACT [UniProtKB:P12236] synonym: "ANT 3" EXACT [UniProtKB:P12236] synonym: "Solute carrier family 25 member 6" EXACT [UniProtKB:P12236] xref: EMBL:AAA36750.1 xref: EMBL:AAG01998.1 xref: EMBL:AAH07295.1 xref: EMBL:AAH07850.1 xref: EMBL:AAH08737.1 xref: EMBL:AAH08935.1 xref: EMBL:AAH14775.1 xref: EMBL:AAH31912.1 xref: UniProtKB:P12236 xref: UniProtKB:Q96C49 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022027 ! SLC25A6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016554 ! ikbkg-slc25a6 physical interaction relationship: participates_in CCO:I0016643 ! map3k1-slc25a6 physical interaction relationship: participates_in CCO:I0016749 ! map3k3-slc25a6 physical interaction relationship: participates_in CCO:I0017028 ! tnfrsf1a-slc25a6 physical interaction relationship: participates_in CCO:I0017080 ! tradd-slc25a6 physical interaction relationship: participates_in CCO:I0019624 ! slc25a6-chd3 physical interaction relationship: participates_in CCO:I0019718 ! fgfr3-slc25a6 physical interaction relationship: participates_in CCO:I0020467 ! strn4-slc25a6 physical interaction relationship: transforms_into CCO:B0065450 ! ADT3_HUMAN-N-acetylthreonine2 relationship: transforms_into CCO:B0065451 ! ADT3_HUMAN-Phosphotyrosine191 [Term] id: CCO:B0063076 name: PRKDC_HUMAN def: "DNA-dependent protein kinase catalytic subunit" [UniProtKB:P78527] synonym: "DNA-PK catalytic subunit" EXACT [UniProtKB:P78527] synonym: "DNA-PKcs" EXACT [UniProtKB:P78527] synonym: "DNPK1" EXACT [UniProtKB:P78527] synonym: "EC 2.7.11.1" EXACT [UniProtKB:P78527] synonym: "p460" EXACT [UniProtKB:P78527] xref: EMBL:AAA79184.1 xref: EMBL:AAA79244.1 xref: EMBL:AAB39925.5 xref: EMBL:AAB51722.1 xref: EMBL:AAC50210.3 xref: EMBL:AAC52019.2 xref: EMBL:AAK40350.1 xref: EMBL:AAP69525.1 xref: EMBL:BAB79635.1 xref: EMBL:BAD92097.1 xref: UniProtKB:P78527 xref: UniProtKB:P78528 xref: UniProtKB:Q13327 xref: UniProtKB:Q13337 xref: UniProtKB:Q14175 xref: UniProtKB:Q59H99 xref: UniProtKB:Q7Z611 xref: UniProtKB:Q96SE6 xref: UniProtKB:Q9UME3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022530 ! PRKDC_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016557 ! ikbkg-prkdc physical interaction relationship: participates_in CCO:I0016755 ! map3k3-prkdc physical interaction relationship: participates_in CCO:I0016827 ! nfkb2-prkdc physical interaction relationship: participates_in CCO:I0016885 ! relb-prkdc physical interaction relationship: participates_in CCO:I0017030 ! tnfrsf1a-prkdc physical interaction relationship: participates_in CCO:I0017082 ! tradd-prkdc physical interaction relationship: transforms_into CCO:B0069516 ! PRKDC_HUMAN-Phosphoserine893 relationship: transforms_into CCO:B0069517 ! PRKDC_HUMAN-Phosphothreonine2603 relationship: transforms_into CCO:B0069518 ! PRKDC_HUMAN-Phosphothreonine2609 relationship: transforms_into CCO:B0069519 ! PRKDC_HUMAN-Phosphoserine2612 relationship: transforms_into CCO:B0069520 ! PRKDC_HUMAN-Phosphothreonine2638 relationship: transforms_into CCO:B0069521 ! PRKDC_HUMAN-Phosphothreonine2647 relationship: transforms_into CCO:B0069522 ! PRKDC_HUMAN-Phosphothreonine2649 relationship: transforms_into CCO:B0069523 ! PRKDC_HUMAN-Phosphotyrosine2743 relationship: transforms_into CCO:B0069524 ! PRKDC_HUMAN-Phosphoserine3205 relationship: transforms_into CCO:B0069525 ! PRKDC_HUMAN-Phosphoserine4026 [Term] id: CCO:B0063077 name: IPO9_HUMAN def: "Importin-9" [UniProtKB:Q96P70] synonym: "Imp9" EXACT [UniProtKB:Q96P70] synonym: "Ran-binding protein 9" EXACT [UniProtKB:Q96P70] synonym: "RanbP9" EXACT [UniProtKB:Q96P70] xref: EMBL:AAF28951.1 xref: EMBL:AAH03604.2 xref: EMBL:AAL01416.1 xref: EMBL:BAA86506.1 xref: EMBL:BAA91588.1 xref: EMBL:BAB55181.1 xref: EMBL:BAC04383.1 xref: EMBL:BAC11173.1 xref: EMBL:CAD38991.1 xref: UniProtKB:Q8N1Y1 xref: UniProtKB:Q8N3I2 xref: UniProtKB:Q8NCG9 xref: UniProtKB:Q96P70 xref: UniProtKB:Q96SU6 xref: UniProtKB:Q9NW01 xref: UniProtKB:Q9P0A8 xref: UniProtKB:Q9ULM8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022341 ! IPO9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016563 ! ikbkg-ipo9 physical interaction relationship: transforms_into CCO:B0067121 ! IPO9_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063078 name: RS16_HUMAN def: "40S ribosomal protein S16" [UniProtKB:P62249] xref: EMBL:AAA60583.1 xref: EMBL:AAH04324.1 xref: EMBL:AAH07977.1 xref: EMBL:BAB79479.1 xref: UniProtKB:P17008 xref: UniProtKB:P62249 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022610 ! RPS16_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016566 ! ikbkg-rps16 physical interaction relationship: participates_in CCO:I0016655 ! map3k1-rps16 physical interaction relationship: participates_in CCO:I0016769 ! map3k3-rps16 physical interaction relationship: participates_in CCO:I0016836 ! nfkb2-rps16 physical interaction relationship: participates_in CCO:I0017036 ! tnfrsf1a-rps16 physical interaction relationship: participates_in CCO:I0017085 ! tradd-rps16 physical interaction [Term] id: CCO:B0063079 name: BAG5_HUMAN def: "BAG family molecular chaperone regulator 5" [UniProtKB:Q9UL15] synonym: "BAG-5" EXACT [UniProtKB:Q9UL15] synonym: "Bcl-2-associated athanogene 5" EXACT [UniProtKB:Q9UL15] xref: EMBL:AAD16124.2 xref: EMBL:AAH44216.2 xref: EMBL:AAH50551.1 xref: EMBL:BAA74896.1 xref: UniProtKB:O94950 xref: UniProtKB:Q86W59 xref: UniProtKB:Q9UL15 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022067 ! BAG5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016597 ! map3k1-bag5 physical interaction relationship: participates_in CCO:I0016677 ! map3k3-bag5 physical interaction [Term] id: CCO:B0063080 name: TCPA_HUMAN def: "T-complex protein 1 subunit alpha" [UniProtKB:P17987] synonym: "CCT-alpha" EXACT [UniProtKB:P17987] synonym: "TCP-1-alpha" EXACT [UniProtKB:P17987] xref: EMBL:AAA61059.1 xref: EMBL:AAA61060.1 xref: EMBL:AAH00665.1 xref: EMBL:AAP35615.1 xref: EMBL:CAA37064.1 xref: EMBL:CAI21851.1 xref: UniProtKB:P17987 xref: UniProtKB:Q15556 xref: UniProtKB:Q5TCM3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022703 ! CCT1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0016609 ! map3k1-cct1 physical interaction relationship: participates_in CCO:I0016701 ! map3k3-cct1 physical interaction relationship: participates_in CCO:I0016967 ! tbk1-cct1 physical interaction relationship: transforms_into CCO:B0071288 ! TCPA_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0071289 ! TCPA_HUMAN-N6-acetyllysine400 relationship: transforms_into CCO:B0071290 ! TCPA_HUMAN-Phosphoserine544 [Term] id: CCO:B0063081 name: SSRD_HUMAN def: "Translocon-associated protein subunit delta precursor" [UniProtKB:P51571] synonym: "Signal sequence receptor subunit delta" EXACT [UniProtKB:P51571] synonym: "SSR-delta" EXACT [UniProtKB:P51571] synonym: "TRAP-delta" EXACT [UniProtKB:P51571] xref: EMBL:AAH03371.1 xref: EMBL:AAP35856.1 xref: EMBL:CAA62211.1 xref: EMBL:CAA92215.1 xref: EMBL:CAA93157.1 xref: UniProtKB:P51571 xref: UniProtKB:Q53XY1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022679 ! SSR4_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000365 ! translocon complex relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0016610 ! map3k1-ssr4 physical interaction relationship: participates_in CCO:I0017003 ! tnfrsf1a-ssr4 physical interaction [Term] id: CCO:B0063082 name: AAAT_HUMAN def: "Neutral amino acid transporter B(0)" [UniProtKB:Q15758] synonym: "ATB(0)" EXACT [UniProtKB:Q15758] synonym: "Baboon M7 virus receptor" EXACT [UniProtKB:Q15758] synonym: "RD114/simian type D retrovirus receptor" EXACT [UniProtKB:Q15758] synonym: "Sodium-dependent neutral amino acid transporter type 2" EXACT [UniProtKB:Q15758] synonym: "Solute carrier family 1 member 5" EXACT [UniProtKB:Q15758] xref: EMBL:AAC50629.1 xref: EMBL:AAD09812.1 xref: EMBL:AAD27806.1 xref: EMBL:AAH00062.1 xref: EMBL:AAK77026.1 xref: UniProtKB:O95720 xref: UniProtKB:Q15758 xref: UniProtKB:Q96RL9 xref: UniProtKB:Q9BWQ3 xref: UniProtKB:Q9UNP2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022019 ! SLC1A5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016611 ! map3k1-slc1a5 physical interaction relationship: participates_in CCO:I0017004 ! tnfrsf1a-slc1a5 physical interaction relationship: participates_in CCO:I0020664 ! slc1a5-tbc1d17 physical interaction relationship: transforms_into CCO:B0065230 ! AAAT_HUMAN-Phosphoserine535 [Term] id: CCO:B0063083 name: RL3_HUMAN def: "60S ribosomal protein L3" [UniProtKB:P39023] synonym: "HIV-1 TAR RNA-binding protein B" EXACT [UniProtKB:P39023] synonym: "TARBP-B" EXACT [UniProtKB:P39023] xref: EMBL:AAA60291.1 xref: EMBL:AAA91344.1 xref: EMBL:AAH02408.1 xref: EMBL:AAH06483.1 xref: EMBL:AAH08003.1 xref: EMBL:AAH12146.1 xref: EMBL:AAH12786.1 xref: EMBL:AAH13674.1 xref: EMBL:AAH14017.1 xref: EMBL:AAH15032.1 xref: EMBL:AAH15767.1 xref: EMBL:AAH63662.1 xref: EMBL:AAH88373.1 xref: EMBL:AAI07712.1 xref: EMBL:BAA25828.1 xref: EMBL:BAB93474.1 xref: EMBL:CAA18450.1 xref: EMBL:CAA51839.1 xref: EMBL:CAG30452.1 xref: UniProtKB:P39023 xref: UniProtKB:Q15548 xref: UniProtKB:Q5I0G0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022580 ! RPL3_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016616 ! map3k1-rpl3 physical interaction relationship: transforms_into CCO:B0070085 ! RL3_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0070086 ! RL3_HUMAN-Phosphotyrosine307 [Term] id: CCO:B0063084 name: ECHB_HUMAN def: "Trifunctional enzyme subunit beta, mitochondrial precursor" [UniProtKB:P55084] synonym: "TP-beta" EXACT [UniProtKB:P55084] xref: EMBL:AAG39280.1 xref: EMBL:AAH14572.1 xref: EMBL:AAH17564.1 xref: EMBL:AAH30824.1 xref: EMBL:AAH66963.1 xref: EMBL:AAY14644.1 xref: EMBL:BAA03942.1 xref: EMBL:BAA22061.1 xref: UniProtKB:O14969 xref: UniProtKB:P55084 xref: UniProtKB:Q53TA6 xref: UniProtKB:Q96C77 xref: UniProtKB:Q9H3F5 xref: UniProtKB:Q9T2V8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022210 ! HADHB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016617 ! map3k1-hadhb physical interaction relationship: participates_in CCO:I0016800 ! nfkb2-hadhb physical interaction relationship: participates_in CCO:I0016911 ! ripk2-hadhb physical interaction relationship: transforms_into CCO:B0065979 ! ECHB_HUMAN-N6-acetyllysine201 relationship: transforms_into CCO:B0065980 ! ECHB_HUMAN-N6-acetyllysine348 [Term] id: CCO:B0063085 name: RS11_HUMAN def: "40S ribosomal protein S11" [UniProtKB:P62280] xref: EMBL:AAH07283.1 xref: EMBL:AAH07603.1 xref: EMBL:AAH07945.1 xref: EMBL:AAH10028.1 xref: EMBL:AAH16378.1 xref: EMBL:AAH70224.1 xref: EMBL:AAI00026.1 xref: EMBL:BAA25818.1 xref: EMBL:BAA88215.1 xref: EMBL:CAA29834.1 xref: UniProtKB:P04643 xref: UniProtKB:P62280 xref: UniProtKB:Q498Y6 xref: UniProtKB:Q6IRY0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022609 ! RPS11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016619 ! map3k1-rps11 physical interaction relationship: participates_in CCO:I0016803 ! nfkb2-rps11 physical interaction relationship: participates_in CCO:I0016872 ! relb-rps11 physical interaction relationship: transforms_into CCO:B0070200 ! RS11_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063086 name: TCPZ_HUMAN def: "T-complex protein 1 subunit zeta" [UniProtKB:P40227] synonym: "Acute morphine dependence-related protein 2" EXACT [UniProtKB:P40227] synonym: "CCT-zeta" EXACT [UniProtKB:P40227] synonym: "CCT-zeta-1" EXACT [UniProtKB:P40227] synonym: "HTR3" EXACT [UniProtKB:P40227] synonym: "TCP-1-zeta" EXACT [UniProtKB:P40227] synonym: "Tcp20" EXACT [UniProtKB:P40227] xref: EMBL:AAA58676.1 xref: EMBL:AAA61061.1 xref: EMBL:AAI06943.1 xref: EMBL:AAK61354.1 xref: EMBL:AAS07451.1 xref: EMBL:BAB61032.1 xref: UniProtKB:P40227 xref: UniProtKB:Q3KP28 xref: UniProtKB:Q75LP4 xref: UniProtKB:Q96S46 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022704 ! CCT6A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016623 ! map3k1-cct6a physical interaction relationship: participates_in CCO:I0016718 ! map3k3-cct6a physical interaction relationship: participates_in CCO:I0016970 ! tbk1-cct6a physical interaction [Term] id: CCO:B0063087 name: GEMI4_HUMAN def: "Component of gems 4" [UniProtKB:P57678] synonym: "Gemin-4" EXACT [UniProtKB:P57678] synonym: "p97" EXACT [UniProtKB:P57678] xref: EMBL:AAF35283.1 xref: EMBL:CAB45743.3 xref: EMBL:CAB45755.1 xref: UniProtKB:P57678 xref: UniProtKB:Q9NZS7 xref: UniProtKB:Q9UG32 xref: UniProtKB:Q9Y4Q2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022272 ! GEMIN4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016624 ! map3k1-gemin4 physical interaction relationship: participates_in CCO:I0016806 ! nfkb2-gemin4 physical interaction relationship: participates_in CCO:I0016912 ! ripk2-gemin4 physical interaction relationship: participates_in CCO:I0018600 ! gemin5-gemin4-1 physical interaction relationship: transforms_into CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 [Term] id: CCO:B0063088 name: RCN2_HUMAN def: "Reticulocalbin-2 precursor" [UniProtKB:Q14257] synonym: "Calcium-binding protein ERC-55" EXACT [UniProtKB:Q14257] synonym: "E6-binding protein" EXACT [UniProtKB:Q14257] synonym: "E6BP" EXACT [UniProtKB:Q14257] xref: EMBL:AAH04892.1 xref: EMBL:CAA55343.1 xref: UniProtKB:Q14257 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022562 ! RCN2_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0016625 ! map3k1-rcn2 physical interaction relationship: participates_in CCO:I0016902 ! ripk1-rcn2 physical interaction relationship: participates_in CCO:I0017015 ! tnfrsf1a-rcn2 physical interaction relationship: participates_in CCO:I0017075 ! tradd-rcn2 physical interaction relationship: participates_in CCO:I0017100 ! traf1-rcn2 physical interaction relationship: participates_in CCO:I0017143 ! traf6-rcn2 physical interaction [Term] id: CCO:B0063089 name: ECHA_HUMAN def: "Trifunctional enzyme subunit alpha, mitochondrial precursor" [UniProtKB:P40939] synonym: "78 kDa gastrin-binding protein" EXACT [UniProtKB:P40939] synonym: "TP-alpha" EXACT [UniProtKB:P40939] xref: EMBL:AAA56664.1 xref: EMBL:AAH09235.1 xref: EMBL:BAA03941.1 xref: UniProtKB:P40939 xref: UniProtKB:Q16679 xref: UniProtKB:Q96GT7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022209 ! HADHA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016628 ! map3k1-hadha physical interaction relationship: participates_in CCO:I0016808 ! nfkb2-hadha physical interaction relationship: participates_in CCO:I0017016 ! tnfrsf1a-hadha physical interaction relationship: participates_in CCO:I0017144 ! traf6-hadha physical interaction relationship: transforms_into CCO:B0065976 ! ECHA_HUMAN-N6-acetyllysine569 relationship: transforms_into CCO:B0065977 ! ECHA_HUMAN-N6-acetyllysine728 relationship: transforms_into CCO:B0065978 ! ECHA_HUMAN-Phosphoserine756 [Term] id: CCO:B0063090 name: RL14_HUMAN def: "60S ribosomal protein L14" [UniProtKB:P50914] synonym: "CAG-ISL 7" EXACT [UniProtKB:P50914] xref: EMBL:AAC16021.1 xref: EMBL:AAH00606.1 xref: EMBL:AAH05134.1 xref: EMBL:AAH09294.1 xref: EMBL:AAH19651.1 xref: EMBL:AAH22805.1 xref: EMBL:AAH29036.1 xref: EMBL:BAA13443.1 xref: EMBL:BAB21253.1 xref: EMBL:BAB79460.1 xref: UniProtKB:P50914 xref: UniProtKB:Q8TBD5 xref: UniProtKB:Q8WUT0 xref: UniProtKB:Q92579 xref: UniProtKB:Q96GR0 xref: UniProtKB:Q9BSB8 xref: UniProtKB:Q9BW65 xref: UniProtKB:Q9BYF6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022570 ! RPL14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016631 ! map3k1-rpl14 physical interaction relationship: transforms_into CCO:B0070063 ! RL14_HUMAN-Phosphoserine139 [Term] id: CCO:B0063091 name: RL35_HUMAN def: "60S ribosomal protein L35" [UniProtKB:P42766] xref: EMBL:AAA51648.1 xref: EMBL:AAH00348.1 xref: EMBL:AAH10919.1 xref: EMBL:AAH71915.1 xref: EMBL:AAH94828.1 xref: EMBL:BAB21255.1 xref: EMBL:CAG33158.1 xref: EMBL:CAI39638.1 xref: EMBL:CAI39639.1 xref: UniProtKB:P42766 xref: UniProtKB:Q4VBY5 xref: UniProtKB:Q5JTN5 xref: UniProtKB:Q6IBC7 xref: UniProtKB:Q96QJ7 xref: UniProtKB:Q9BYF4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022578 ! RPL35_human relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0016646 ! map3k1-rpl35 physical interaction [Term] id: CCO:B0063092 name: HS105_HUMAN def: "Heat shock protein 105 kDa" [UniProtKB:Q92598] synonym: "Antigen NY-CO-25" EXACT [UniProtKB:Q92598] synonym: "Heat shock 110 kDa protein" EXACT [UniProtKB:Q92598] xref: EMBL:AAC18044.1 xref: EMBL:AAH37553.1 xref: EMBL:BAA13192.2 xref: EMBL:BAA34779.1 xref: EMBL:BAA34780.1 xref: EMBL:CAI12428.1 xref: EMBL:CAI12429.1 xref: EMBL:CAI12430.1 xref: EMBL:EAX08482.1 xref: UniProtKB:O95739 xref: UniProtKB:Q5TBM6 xref: UniProtKB:Q5TBM7 xref: UniProtKB:Q5TBM8 xref: UniProtKB:Q92598 xref: UniProtKB:Q9UPC4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022317 ! HSPH1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0016647 ! map3k1-hsph1 physical interaction relationship: participates_in CCO:I0020336 ! hsph1-chd3 physical interaction relationship: transforms_into CCO:B0066913 ! HS105_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0066914 ! HS105_HUMAN-Phosphoserine384 relationship: transforms_into CCO:B0066915 ! HS105_HUMAN-Phosphoserine509 relationship: transforms_into CCO:B0066916 ! HS105_HUMAN-Phosphoserine557 relationship: transforms_into CCO:B0066917 ! HS105_HUMAN-Phosphothreonine700 relationship: transforms_into CCO:B0066918 ! HS105_HUMAN-Phosphoserine809 relationship: transforms_into CCO:B0066919 ! HS105_HUMAN-Phosphothreonine815 [Term] id: CCO:B0063093 name: RL10_HUMAN def: "60S ribosomal protein L10" [UniProtKB:P27635] synonym: "Laminin receptor homolog" EXACT [UniProtKB:P27635] synonym: "Protein QM" EXACT [UniProtKB:P27635] synonym: "Tumor suppressor QM" EXACT [UniProtKB:P27635] xref: EMBL:AAA36021.1 xref: EMBL:AAA36378.1 xref: EMBL:AAA63253.1 xref: EMBL:AAA92646.1 xref: EMBL:AAB22173.1 xref: EMBL:AAB27665.1 xref: EMBL:AAH03358.1 xref: EMBL:AAH26276.1 xref: EMBL:AAH71918.1 xref: EMBL:AAL88713.1 xref: EMBL:ABC88559.1 xref: EMBL:ABC88560.1 xref: EMBL:ABC88561.1 xref: EMBL:ABC88562.1 xref: EMBL:ABC88563.1 xref: EMBL:ABC88564.1 xref: EMBL:ABC88565.1 xref: EMBL:ABC88566.1 xref: EMBL:ABC88567.1 xref: EMBL:ABC88568.1 xref: EMBL:ABC88569.1 xref: EMBL:ABC88570.1 xref: EMBL:ABC88571.1 xref: EMBL:ABC88572.1 xref: EMBL:BAA28595.1 xref: EMBL:BAD97029.1 xref: EMBL:CAG33078.1 xref: EMBL:CAG46866.1 xref: EMBL:CAI43214.1 xref: EMBL:CAI43230.1 xref: EMBL:CAM45852.1 xref: EMBL:CAM45853.1 xref: UniProtKB:A3KQT0 xref: UniProtKB:P27635 xref: UniProtKB:Q16470 xref: UniProtKB:Q2HXT7 xref: UniProtKB:Q53FH7 xref: UniProtKB:Q6FGN8 xref: UniProtKB:Q8TDA5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022569 ! RPL10_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016650 ! map3k1-rpl10 physical interaction relationship: participates_in CCO:I0020441 ! rpl10-tbpl1 physical interaction [Term] id: CCO:B0063094 name: USP9X_HUMAN def: "Probable ubiquitin carboxyl-terminal hydrolase FAF-X" [UniProtKB:Q93008] synonym: "Deubiquitinating enzyme FAF-X" EXACT [UniProtKB:Q93008] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q93008] synonym: "Fat facets protein-related, X-linked" EXACT [UniProtKB:Q93008] synonym: "Ubiquitin thioesterase FAF-X" EXACT [UniProtKB:Q93008] synonym: "Ubiquitin-specific protease 9, X chromosome" EXACT [UniProtKB:Q93008] synonym: "Ubiquitin-specific-processing protease FAF-X" EXACT [UniProtKB:Q93008] xref: EMBL:AAC25395.1 xref: EMBL:CAA66942.1 xref: EMBL:CAD13527.2 xref: EMBL:CAD18900.2 xref: UniProtKB:O75550 xref: UniProtKB:Q8WWT3 xref: UniProtKB:Q8WX12 xref: UniProtKB:Q93008 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022768 ! USP9X_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016653 ! map3k1-usp9x physical interaction relationship: participates_in CCO:I0016835 ! nfkb2-usp9x physical interaction relationship: participates_in CCO:I0016889 ! relb-usp9x physical interaction relationship: transforms_into CCO:B0071756 ! USP9X_HUMAN-Phosphoserine1593 relationship: transforms_into CCO:B0071757 ! USP9X_HUMAN-Phosphotyrosine1808 relationship: transforms_into CCO:B0071758 ! USP9X_HUMAN-Phosphoserine2436 relationship: transforms_into CCO:B0071759 ! USP9X_HUMAN-Phosphotyrosine2533 relationship: transforms_into CCO:B0071760 ! USP9X_HUMAN-Phosphoserine2540 [Term] id: CCO:B0063095 name: RPAP3_HUMAN def: "RNA polymerase II-associated protein 3" [UniProtKB:Q9H6T3] xref: EMBL:AAH56415.1 xref: EMBL:BAB15170.1 xref: EMBL:EAW57938.1 xref: UniProtKB:Q6PHR5 xref: UniProtKB:Q9H6T3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022601 ! RPAP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016661 ! map3k3-q9h6t3 physical interaction relationship: transforms_into CCO:B0070152 ! RPAP3_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0070153 ! RPAP3_HUMAN-Phosphothreonine111 relationship: transforms_into CCO:B0070154 ! RPAP3_HUMAN-Phosphoserine116 relationship: transforms_into CCO:B0070155 ! RPAP3_HUMAN-Phosphoserine119 relationship: transforms_into CCO:B0070156 ! RPAP3_HUMAN-Phosphoserine121 relationship: transforms_into CCO:B0070157 ! RPAP3_HUMAN-Phosphoserine481 [Term] id: CCO:B0063096 name: HSP74_HUMAN def: "Heat shock 70 kDa protein 4" [UniProtKB:P34932] synonym: "Heat shock 70-related protein APG-2" EXACT [UniProtKB:P34932] synonym: "HSP70RY" EXACT [UniProtKB:P34932] xref: EMBL:AAA02807.1 xref: EMBL:AAI10862.1 xref: EMBL:AAI26123.1 xref: EMBL:AAI26125.1 xref: EMBL:BAA75062.1 xref: UniProtKB:O95756 xref: UniProtKB:P34932 xref: UniProtKB:Q2TAL4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022322 ! HSPA4_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016665 ! map3k3-hspa4 physical interaction relationship: participates_in CCO:I0016922 ! map3k7ip1-hspa4 physical interaction relationship: participates_in CCO:I0017113 ! traf2-hspa4 physical interaction relationship: transforms_into CCO:B0066927 ! HSP74_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0066928 ! HSP74_HUMAN-Phosphotyrosine89 relationship: transforms_into CCO:B0066929 ! HSP74_HUMAN-Phosphotyrosine336 relationship: transforms_into CCO:B0066930 ! HSP74_HUMAN-Phosphothreonine538 relationship: transforms_into CCO:B0066931 ! HSP74_HUMAN-Phosphoserine552 relationship: transforms_into CCO:B0066932 ! HSP74_HUMAN-Phosphotyrosine660 [Term] id: CCO:B0063097 name: TMOD3_HUMAN def: "Tropomodulin-3" [UniProtKB:Q9NYL9] synonym: "U-Tmod" EXACT [UniProtKB:Q9NYL9] synonym: "Ubiquitous tropomodulin" EXACT [UniProtKB:Q9NYL9] xref: EMBL:AAF31670.1 xref: EMBL:AAF45299.1 xref: EMBL:AAH20542.1 xref: EMBL:CAB70801.1 xref: UniProtKB:Q9NT43 xref: UniProtKB:Q9NYL9 xref: UniProtKB:Q9NZR0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022724 ! TMOD3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016671 ! map3k3-tmod3 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0071434 ! TMOD3_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0071435 ! TMOD3_HUMAN-Phosphoserine71 [Term] id: CCO:B0063098 name: PFD6_HUMAN def: "Prefoldin subunit 6" [UniProtKB:O15212] synonym: "Protein Ke2" EXACT [UniProtKB:O15212] xref: EMBL:AAH39033.1 xref: EMBL:AAH59783.1 xref: EMBL:CAB09993.1 xref: UniProtKB:O15212 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022507 ! PFDN6_human relationship: has_function CCO:F0001238 ! retinoid-X receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004420 ! thyroid hormone receptor coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0005774 ! retinoic acid receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0016673 ! map3k3-pfdn6 physical interaction [Term] id: CCO:B0063099 name: UBL4A_HUMAN def: "Ubiquitin-like protein 4A" [UniProtKB:P11441] synonym: "Ubiquitin-like protein GDX" EXACT [UniProtKB:P11441] xref: EMBL:AAA36790.1 xref: EMBL:AAA92650.1 xref: EMBL:AAH43346.1 xref: EMBL:AAH53589.1 xref: UniProtKB:P11441 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022756 ! UBL4A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016674 ! map3k3-ubl4 physical interaction relationship: transforms_into CCO:B0071668 ! UBL4A_HUMAN-N6-acetyllysine48 relationship: transforms_into CCO:B0071669 ! UBL4A_HUMAN-N6-acetyllysine54 relationship: transforms_into CCO:B0071670 ! UBL4A_HUMAN-Phosphoserine126 [Term] id: CCO:B0063100 name: SERA_HUMAN def: "D-3-phosphoglycerate dehydrogenase" [UniProtKB:O43175] synonym: "3-PGDH" EXACT [UniProtKB:O43175] synonym: "EC 1.1.1.95" EXACT [UniProtKB:O43175] xref: EMBL:AAB88664.1 xref: EMBL:AAD51415.1 xref: EMBL:AAH00303.1 xref: EMBL:AAH01349.1 xref: EMBL:AAH11262.1 xref: EMBL:CAG33076.1 xref: EMBL:CAI22212.1 xref: EMBL:CAI22407.1 xref: UniProtKB:O43175 xref: UniProtKB:Q5SZU3 xref: UniProtKB:Q9BQ01 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022640 ! PHGDH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016687 ! map3k3-phgdh physical interaction relationship: transforms_into CCO:B0070376 ! SERA_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063101 name: MYO1B_HUMAN def: "Myosin-Ib" [UniProtKB:O43795] synonym: "MMI-alpha" EXACT [UniProtKB:O43795] synonym: "MMIa" EXACT [UniProtKB:O43795] synonym: "MYH-1c" EXACT [UniProtKB:O43795] synonym: "Myosin I alpha" EXACT [UniProtKB:O43795] xref: EMBL:AAH53558.1 xref: EMBL:CAA04712.1 xref: EMBL:CAA04713.1 xref: UniProtKB:O43794 xref: UniProtKB:O43795 xref: UniProtKB:Q7Z6L5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022419 ! MYO1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000788 ! myosin complex relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016692 ! map3k3-myo1b physical interaction [Term] id: CCO:B0063102 name: SCO2_HUMAN def: "Protein SCO2 homolog, mitochondrial precursor" [UniProtKB:O43819] xref: EMBL:AAF05313.1 xref: EMBL:AAI02025.1 xref: EMBL:AAI02026.1 xref: EMBL:CAA16671.1 xref: EMBL:CAG30455.1 xref: UniProtKB:O43819 xref: UniProtKB:Q3T1B5 xref: UniProtKB:Q9UK87 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022638 ! SCO2_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: participates_in CCO:I0016695 ! map3k3-sco2 physical interaction [Term] id: CCO:B0063103 name: PFD4_HUMAN def: "Prefoldin subunit 4" [UniProtKB:Q9NQP4] synonym: "Protein C-1" EXACT [UniProtKB:Q9NQP4] xref: EMBL:AAB17063.1 xref: EMBL:AAH10953.1 xref: EMBL:CAI19316.1 xref: UniProtKB:Q5TD11 xref: UniProtKB:Q92779 xref: UniProtKB:Q9NQP4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022506 ! PFDN4_human relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0016697 ! map3k3-pfdn4 physical interaction relationship: transforms_into CCO:B0069238 ! PFD4_HUMAN-Phosphoserine125 [Term] id: CCO:B0063104 name: PLOD1_HUMAN def: "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor" [UniProtKB:Q02809] synonym: "EC 1.14.11.4" EXACT [UniProtKB:Q02809] synonym: "LH1" EXACT [UniProtKB:Q02809] synonym: "Lysyl hydroxylase 1" EXACT [UniProtKB:Q02809] xref: EMBL:AAA60116.1 xref: EMBL:AAH16657.1 xref: EMBL:AAM12752.1 xref: EMBL:CAC19722.1 xref: UniProtKB:Q02809 xref: UniProtKB:Q96AV9 xref: UniProtKB:Q9H132 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022520 ! PLOD1_human relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001936 ! procollagen-lysine 5-dioxygenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors relationship: has_function CCO:F0004662 ! L-ascorbic acid binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001057 ! rough endoplasmic reticulum membrane relationship: participates_in CCO:I0016717 ! map3k3-plod physical interaction [Term] id: CCO:B0063105 name: Q9C083_HUMAN def: "MM-1 gamma" [UniProtKB:Q9C083] synonym: "Prefoldin subunit 5, isoform CRA_c" EXACT [UniProtKB:Q9C083] xref: EMBL:BAB32646.1 xref: EMBL:EAW96685.1 xref: UniProtKB:Q9C083 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022859 ! mm-1_human relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0016719 ! map3k3-mm_1 physical interaction [Term] id: CCO:B0063106 name: F10A1_HUMAN def: "Hsc70-interacting protein" [UniProtKB:P50502] synonym: "Hip" EXACT [UniProtKB:P50502] synonym: "Progesterone receptor-associated p48 protein" EXACT [UniProtKB:P50502] synonym: "Protein FAM10A1" EXACT [UniProtKB:P50502] synonym: "Putative tumor suppressor ST13" EXACT [UniProtKB:P50502] synonym: "Renal carcinoma antigen NY-REN-33" EXACT [UniProtKB:P50502] synonym: "Suppression of tumorigenicity protein 13" EXACT [UniProtKB:P50502] xref: EMBL:AAB38382.1 xref: EMBL:AAC97526.1 xref: EMBL:AAH52982.1 xref: EMBL:AAH71629.1 xref: EMBL:CAB10844.1 xref: EMBL:CAG30472.1 xref: UniProtKB:O14999 xref: UniProtKB:P50502 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022236 ! ST13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016720 ! map3k3-st13 physical interaction relationship: participates_in CCO:I0020343 ! igsf2-st13 physical interaction relationship: transforms_into CCO:B0066035 ! F10A1_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0066036 ! F10A1_HUMAN-Phosphoserine76 relationship: transforms_into CCO:B0066037 ! F10A1_HUMAN-Phosphoserine79 relationship: transforms_into CCO:B0066038 ! F10A1_HUMAN-Phosphoserine181 [Term] id: CCO:B0063107 name: RL40_HUMAN def: "60S ribosomal protein L40" [UniProtKB:P62987] synonym: "CEP52" EXACT [UniProtKB:P62987] xref: EMBL:AAC25582.1 xref: EMBL:AAK31162.1 xref: EMBL:CAA40312.1 xref: EMBL:CAA40313.1 xref: EMBL:CAA40314.1 xref: EMBL:CAA68439.1 xref: UniProtKB:P14793 xref: UniProtKB:P62987 xref: UniProtKB:Q9BX98 xref: UniProtKB:Q9UPK7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005864 ! UBA52_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016725 ! map3k3-uba52-1 physical interaction relationship: participates_in CCO:I0017020 ! tnfrsf1a-uba52 physical interaction relationship: transforms_into CCO:B0070087 ! RL40_HUMAN-N6,N6,N6-trimethyllysine22 [Term] id: CCO:B0063108 name: PIHD1_HUMAN def: "PIH1 domain-containing protein 1" [UniProtKB:Q9NWS0] synonym: "Nucleolar protein 17 homolog" EXACT [UniProtKB:Q9NWS0] xref: EMBL:AAH01108.1 xref: EMBL:BAA91307.1 xref: UniProtKB:Q9BVL0 xref: UniProtKB:Q9NWS0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022514 ! PIH1D1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016728 ! map3k3-q9nws0 physical interaction [Term] id: CCO:B0063109 name: Q96LM8_HUMAN def: "cDNA FLJ25361 fis, clone TST01713" [UniProtKB:Q96LM8] xref: EMBL:BAB71660.1 xref: UniProtKB:Q96LM8 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016730 ! map3k3-q96lm8 physical interaction [Term] id: CCO:B0063110 name: Q8N532_HUMAN def: "TUBA1C protein" [UniProtKB:Q8N532] xref: EMBL:AAH33064.1 xref: UniProtKB:Q8N532 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008266 ! TUBA1C_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0016732 ! map3k3-q8n532 physical interaction [Term] id: CCO:B0063111 name: LAP4_HUMAN def: "Protein LAP4" [UniProtKB:Q14160] synonym: "hScrib" EXACT [UniProtKB:Q14160] synonym: "Protein scribble homolog" EXACT [UniProtKB:Q14160] xref: EMBL:AAH09490.2 xref: EMBL:AAH14632.2 xref: EMBL:AAH63590.1 xref: EMBL:AAL38976.1 xref: EMBL:AAP88017.1 xref: EMBL:AAP88018.1 xref: EMBL:BAA09768.3 xref: UniProtKB:Q14160 xref: UniProtKB:Q6P496 xref: UniProtKB:Q7Z5D1 xref: UniProtKB:Q8WWV8 xref: UniProtKB:Q96C69 xref: UniProtKB:Q96GG1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022360 ! SCRIB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016733 ! map3k3-kiaa0147 physical interaction relationship: transforms_into CCO:B0067540 ! LAP4_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0067541 ! LAP4_HUMAN-Phosphoserine487 relationship: transforms_into CCO:B0067542 ! LAP4_HUMAN-Phosphoserine504 relationship: transforms_into CCO:B0067543 ! LAP4_HUMAN-Phosphothreonine689 relationship: transforms_into CCO:B0067544 ! LAP4_HUMAN-Phosphothreonine749 relationship: transforms_into CCO:B0067545 ! LAP4_HUMAN-Phosphothreonine826 relationship: transforms_into CCO:B0067546 ! LAP4_HUMAN-Phosphotyrosine834 relationship: transforms_into CCO:B0067547 ! LAP4_HUMAN-Phosphoserine835 relationship: transforms_into CCO:B0067548 ! LAP4_HUMAN-Phosphoserine853 relationship: transforms_into CCO:B0067549 ! LAP4_HUMAN-Phosphoserine939 relationship: transforms_into CCO:B0067550 ! LAP4_HUMAN-Phosphothreonine941 relationship: transforms_into CCO:B0067551 ! LAP4_HUMAN-Phosphoserine1140 relationship: transforms_into CCO:B0067552 ! LAP4_HUMAN-Phosphoserine1220 relationship: transforms_into CCO:B0067553 ! LAP4_HUMAN-Phosphoserine1223 relationship: transforms_into CCO:B0067554 ! LAP4_HUMAN-Phosphoserine1225 relationship: transforms_into CCO:B0067555 ! LAP4_HUMAN-Phosphoserine1226 relationship: transforms_into CCO:B0067556 ! LAP4_HUMAN-Phosphoserine1232 relationship: transforms_into CCO:B0067557 ! LAP4_HUMAN-Phosphoserine1306 relationship: transforms_into CCO:B0067558 ! LAP4_HUMAN-Phosphoserine1309 relationship: transforms_into CCO:B0067559 ! LAP4_HUMAN-Phosphothreonine1342 relationship: transforms_into CCO:B0067560 ! LAP4_HUMAN-Phosphoserine1348 relationship: transforms_into CCO:B0067561 ! LAP4_HUMAN-Phosphotyrosine1360 relationship: transforms_into CCO:B0067562 ! LAP4_HUMAN-Phosphoserine1378 relationship: transforms_into CCO:B0067563 ! LAP4_HUMAN-Phosphoserine1437 relationship: transforms_into CCO:B0067564 ! LAP4_HUMAN-Phosphoserine1439 relationship: transforms_into CCO:B0067565 ! LAP4_HUMAN-Phosphoserine1448 relationship: transforms_into CCO:B0067566 ! LAP4_HUMAN-Phosphoserine1475 relationship: transforms_into CCO:B0067567 ! LAP4_HUMAN-Phosphoserine1486 relationship: transforms_into CCO:B0067568 ! LAP4_HUMAN-Phosphoserine1508 relationship: transforms_into CCO:B0067569 ! LAP4_HUMAN-Phosphoserine1547 relationship: transforms_into CCO:B0067570 ! LAP4_HUMAN-Phosphoserine1561 relationship: transforms_into CCO:B0067571 ! LAP4_HUMAN-Phosphoserine1566 [Term] id: CCO:B0063112 name: UXT_HUMAN def: "Protein UXT" [UniProtKB:Q9UBK9] synonym: "Androgen receptor trapped clone 27 protein" EXACT [UniProtKB:Q9UBK9] synonym: "ART-27" EXACT [UniProtKB:Q9UBK9] synonym: "Ubiquitously expressed transcript protein" EXACT [UniProtKB:Q9UBK9] xref: EMBL:AAD28698.1 xref: EMBL:AAD39839.1 xref: EMBL:AAD39840.1 xref: EMBL:AAH00720.1 xref: EMBL:AAH08890.1 xref: EMBL:CAI42447.1 xref: EMBL:CAI42448.1 xref: UniProtKB:Q5JZG3 xref: UniProtKB:Q9UBK9 xref: UniProtKB:Q9Y6E5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022769 ! UXT_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000149 ! gamma-tubulin complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0016734 ! map3k3-uxt physical interaction [Term] id: CCO:B0063113 name: MYPT1_HUMAN def: "Protein phosphatase 1 regulatory subunit 12A" [UniProtKB:O14974] synonym: "Myosin phosphatase target subunit 1" EXACT [UniProtKB:O14974] synonym: "Myosin phosphatase-targeting subunit 1" EXACT [UniProtKB:O14974] synonym: "Protein phosphatase myosin-binding subunit" EXACT [UniProtKB:O14974] xref: EMBL:AAH47898.1 xref: EMBL:AAH92481.1 xref: EMBL:AAI11753.1 xref: EMBL:AAM49717.1 xref: EMBL:AAQ88438.1 xref: EMBL:BAA22378.1 xref: EMBL:BAB39107.1 xref: UniProtKB:O14974 xref: UniProtKB:Q2NKL4 xref: UniProtKB:Q569H0 xref: UniProtKB:Q86WU3 xref: UniProtKB:Q8NFR6 xref: UniProtKB:Q9BYH0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022424 ! PPP1R12A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016741 ! map3k3-ppp1r12a physical interaction relationship: transforms_into CCO:B0068403 ! MYPT1_HUMAN-Phosphoserine422 relationship: transforms_into CCO:B0068404 ! MYPT1_HUMAN-Phosphothreonine443 relationship: transforms_into CCO:B0068405 ! MYPT1_HUMAN-Phosphoserine445 relationship: transforms_into CCO:B0068406 ! MYPT1_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0068407 ! MYPT1_HUMAN-Phosphothreonine508 relationship: transforms_into CCO:B0068408 ! MYPT1_HUMAN-Phosphoserine509 relationship: transforms_into CCO:B0068409 ! MYPT1_HUMAN-Phosphoserine566 relationship: transforms_into CCO:B0068410 ! MYPT1_HUMAN-Phosphoserine569 relationship: transforms_into CCO:B0068411 ! MYPT1_HUMAN-Phosphothreonine696 relationship: transforms_into CCO:B0068412 ! MYPT1_HUMAN-Phosphoserine852 relationship: transforms_into CCO:B0068413 ! MYPT1_HUMAN-Phosphoserine871 relationship: transforms_into CCO:B0068414 ! MYPT1_HUMAN-Phosphotyrosine890 relationship: transforms_into CCO:B0068415 ! MYPT1_HUMAN-Phosphotyrosine901 relationship: transforms_into CCO:B0068416 ! MYPT1_HUMAN-Phosphoserine910 relationship: transforms_into CCO:B0068417 ! MYPT1_HUMAN-Phosphotyrosine911 [Term] id: CCO:B0063114 name: Q8N8K8_HUMAN def: "Lon protease homolog" [UniProtKB:Q8N8K8] synonym: "EC 3.4.21.-" EXACT [UniProtKB:Q8N8K8] xref: EMBL:BAC04829.1 xref: UniProtKB:Q8N8K8 is_a: CCO:U0000007 ! cell cycle protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000645 ! ATP-dependent peptidase activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016750 ! map3k3-q8n8k8 physical interaction [Term] id: CCO:B0063115 name: F10A4_HUMAN def: "Protein FAM10A4" [UniProtKB:Q8IZP2] xref: EMBL:AAN16377.1 xref: UniProtKB:Q8IZP2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022237 ! FAM10A4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016751 ! map3k3-q8izp2 physical interaction relationship: transforms_into CCO:B0066039 ! F10A4_HUMAN-Phosphoserine71 relationship: transforms_into CCO:B0066040 ! F10A4_HUMAN-Phosphoserine72 relationship: transforms_into CCO:B0066041 ! F10A4_HUMAN-Phosphoserine75 [Term] id: CCO:B0063116 name: PYGM_HUMAN def: "Glycogen phosphorylase, muscle form" [UniProtKB:P11217] synonym: "EC 2.4.1.1" EXACT [UniProtKB:P11217] synonym: "Myophosphorylase" EXACT [UniProtKB:P11217] xref: EMBL:AAA36216.1 xref: EMBL:AAA60231.1 xref: EMBL:AAC17451.1 xref: EMBL:AAC52081.1 xref: EMBL:AAI26393.1 xref: EMBL:AAI30515.1 xref: EMBL:CAA26834.1 xref: UniProtKB:A0AVK1 xref: UniProtKB:P11217 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022546 ! PYGM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016752 ! map3k3-pygm physical interaction relationship: transforms_into CCO:B0069646 ! PYGM_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0069647 ! PYGM_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0069648 ! PYGM_HUMAN-Phosphotyrosine473 [Term] id: CCO:B0063117 name: Q9UFQ0_HUMAN def: "Putative uncharacterized protein DKFZp434K0435" [UniProtKB:Q9UFQ0] xref: EMBL:CAB55973.1 xref: UniProtKB:Q9UFQ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022863 ! DKFZp434K0435_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016754 ! map3k3-dkfzp434k0435 physical interaction [Term] id: CCO:B0063118 name: LEG7_HUMAN def: "Galectin-7" [UniProtKB:P47929] synonym: "Gal-7" EXACT [UniProtKB:P47929] synonym: "HKL-14" EXACT [UniProtKB:P47929] synonym: "p53-induced gene 1 protein" EXACT [UniProtKB:P47929] synonym: "PI7" EXACT [UniProtKB:P47929] xref: EMBL:AAA67899.1 xref: EMBL:AAA86820.1 xref: EMBL:AAH42911.2 xref: EMBL:AAH61588.1 xref: EMBL:AAH73743.1 xref: UniProtKB:P47929 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022367 ! LGALS7_human relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016758 ! map3k3-lgals7 physical interaction [Term] id: CCO:B0063119 name: SC16A_HUMAN def: "Protein transport protein Sec16A" [UniProtKB:O15027] synonym: "Protein SEC16 homolog A" EXACT [UniProtKB:O15027] xref: EMBL:AAH08332.1 xref: EMBL:AAH28183.1 xref: EMBL:ABI78944.1 xref: EMBL:BAA20769.4 xref: EMBL:CAI13949.1 xref: EMBL:CAI13951.1 xref: EMBL:CAI13952.1 xref: UniProtKB:A1YCA4 xref: UniProtKB:O15027 xref: UniProtKB:Q5SXP0 xref: UniProtKB:Q5SXP1 xref: UniProtKB:Q8N347 xref: UniProtKB:Q96HP1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022637 ! SEC16A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016759 ! map3k3-kiaa0310 physical interaction relationship: transforms_into CCO:B0070327 ! SC16A_HUMAN-Phosphoserine136 relationship: transforms_into CCO:B0070328 ! SC16A_HUMAN-Phosphothreonine415 relationship: transforms_into CCO:B0070329 ! SC16A_HUMAN-Phosphoserine417 relationship: transforms_into CCO:B0070330 ! SC16A_HUMAN-Phosphoserine1149 relationship: transforms_into CCO:B0070331 ! SC16A_HUMAN-Phosphoserine1169 relationship: transforms_into CCO:B0070332 ! SC16A_HUMAN-Phosphoserine1190 relationship: transforms_into CCO:B0070333 ! SC16A_HUMAN-Phosphoserine1191 relationship: transforms_into CCO:B0070334 ! SC16A_HUMAN-Phosphoserine1786 relationship: transforms_into CCO:B0070335 ! SC16A_HUMAN-Phosphoserine1844 relationship: transforms_into CCO:B0070336 ! SC16A_HUMAN-Phosphothreonine1876 relationship: transforms_into CCO:B0070337 ! SC16A_HUMAN-Phosphoserine1903 relationship: transforms_into CCO:B0070338 ! SC16A_HUMAN-Phosphoserine1905 relationship: transforms_into CCO:B0070339 ! SC16A_HUMAN-Phosphoserine2107 [Term] id: CCO:B0063120 name: DNJC7_HUMAN def: "DnaJ homolog subfamily C member 7" [UniProtKB:Q99615] synonym: "Tetratricopeptide repeat protein 2" EXACT [UniProtKB:Q99615] synonym: "TPR repeat protein 2" EXACT [UniProtKB:Q99615] xref: EMBL:AAB36872.1 xref: EMBL:AAH11837.2 xref: EMBL:AAH33772.1 xref: UniProtKB:Q99615 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022191 ! DNAJC7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016764 ! map3k3-dnajc7 physical interaction relationship: participates_in CCO:I0016934 ! map3k7ip1-dnajc7 physical interaction relationship: transforms_into CCO:B0065955 ! DNJC7_HUMAN-Phosphotyrosine50 [Term] id: CCO:B0063121 name: MYO1A_HUMAN def: "Myosin-Ia" [UniProtKB:Q9UBC5] synonym: "BBM-I" EXACT [UniProtKB:Q9UBC5] synonym: "BBMI" EXACT [UniProtKB:Q9UBC5] synonym: "Brush border myosin I" EXACT [UniProtKB:Q9UBC5] synonym: "MIHC" EXACT [UniProtKB:Q9UBC5] synonym: "Myosin I heavy chain" EXACT [UniProtKB:Q9UBC5] xref: EMBL:AAC27437.1 xref: EMBL:AAC78645.1 xref: EMBL:AAD31189.1 xref: EMBL:AAH59387.1 xref: UniProtKB:Q9UBC5 xref: UniProtKB:Q9UQD7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022418 ! MYO1A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000460 ! brush border relationship: located_in CCO:C0000706 ! basal plasma membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000783 ! lateral plasma membrane relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0001056 ! cortical actin cytoskeleton relationship: located_in CCO:C0001356 ! filamentous actin relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0016765 ! map3k3-myo1a physical interaction [Term] id: CCO:B0063122 name: U5S1_HUMAN def: "116 kDa U5 small nuclear ribonucleoprotein component" [UniProtKB:Q15029] synonym: "Elongation factor Tu GTP-binding domain-containing protein 2" EXACT [UniProtKB:Q15029] synonym: "hSNU114" EXACT [UniProtKB:Q15029] synonym: "U5 snRNP-specific protein, 116 kDa" EXACT [UniProtKB:Q15029] synonym: "U5-116 kDa" EXACT [UniProtKB:Q15029] xref: EMBL:AAH02360.1 xref: EMBL:BAA04699.2 xref: UniProtKB:Q15029 xref: UniProtKB:Q9BUR0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022752 ! EFTUD2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0016777 ! nfkb2-snrp116 physical interaction relationship: transforms_into CCO:B0071659 ! U5S1_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0071660 ! U5S1_HUMAN-Phosphothreonine86 [Term] id: CCO:B0063123 name: Q12803_HUMAN def: "Leukophysin (ATP-dependent RNA helicase A)" [UniProtKB:Q12803] xref: EMBL:AAA03571.1 xref: EMBL:BAG70062.1 xref: EMBL:BAG70186.1 xref: UniProtKB:Q12803 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022832 ! LKP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016811 ! nfkb2-lkp physical interaction [Term] id: CCO:B0063124 name: H2B1B_HUMAN def: "Histone H2B type 1-B" [UniProtKB:P33778] synonym: "H2B.1" EXACT [UniProtKB:P33778] synonym: "H2B.f" EXACT [UniProtKB:P33778] synonym: "H2B/f" EXACT [UniProtKB:P33778] xref: EMBL:AAH96728.1 xref: EMBL:AAN06685.1 xref: EMBL:CAA40406.1 xref: UniProtKB:P33778 xref: UniProtKB:Q4KN36 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022297 ! HIST1H2BB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016833 ! nfkb2-hist1h2bb physical interaction relationship: participates_in CCO:I0017034 ! tnfrsf1a-hist1h2bb physical interaction relationship: transforms_into CCO:B0066698 ! H2B1B_HUMAN-N6-acetyllysine6 relationship: transforms_into CCO:B0066699 ! H2B1B_HUMAN-N6-acetyllysine12 relationship: transforms_into CCO:B0066700 ! H2B1B_HUMAN-N6-acetyllysine13 relationship: transforms_into CCO:B0066701 ! H2B1B_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0066702 ! H2B1B_HUMAN-N6-acetyllysine16 relationship: transforms_into CCO:B0066703 ! H2B1B_HUMAN-N6-acetyllysine17 relationship: transforms_into CCO:B0066704 ! H2B1B_HUMAN-N6-acetyllysine21 relationship: transforms_into CCO:B0066705 ! H2B1B_HUMAN-N6-acetyllysine24 relationship: transforms_into CCO:B0066706 ! H2B1B_HUMAN-N6-methylated lysine47 relationship: transforms_into CCO:B0066707 ! H2B1B_HUMAN-N6-methylated lysine58 relationship: transforms_into CCO:B0066708 ! H2B1B_HUMAN-N6-acetyllysine109 relationship: transforms_into CCO:B0066709 ! H2B1B_HUMAN-lysine109 [Term] id: CCO:B0063125 name: DHB4_HUMAN def: "Peroxisomal multifunctional enzyme type 2" [UniProtKB:P51659] synonym: "17-beta-HSD 4" EXACT [UniProtKB:P51659] synonym: "17-beta-hydroxysteroid dehydrogenase 4" EXACT [UniProtKB:P51659] synonym: "D-bifunctional protein" EXACT [UniProtKB:P51659] synonym: "DBP" EXACT [UniProtKB:P51659] synonym: "MFE-2" EXACT [UniProtKB:P51659] xref: EMBL:AAD08652.1 xref: EMBL:AAH03098.1 xref: EMBL:CAA60643.1 xref: UniProtKB:P51659 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022184 ! HSD17B4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016868 ! relb-hsd17b4 physical interaction relationship: transforms_into CCO:B0065946 ! DHB4_HUMAN-Phosphoserine3 relationship: transforms_into CCO:B0065947 ! DHB4_HUMAN-Phosphoserine309 relationship: transforms_into CCO:B0065948 ! DHB4_HUMAN-N6-acetyllysine663 [Term] id: CCO:B0063126 name: CPSF6_HUMAN def: "Cleavage and polyadenylation specificity factor subunit 6" [UniProtKB:Q16630] synonym: "Cleavage and polyadenylation specificity factor 68 kDa subunit" EXACT [UniProtKB:Q16630] synonym: "CPSF 68 kDa subunit" EXACT [UniProtKB:Q16630] synonym: "Pre-mRNA cleavage factor Im 68 kDa subunit" EXACT [UniProtKB:Q16630] synonym: "Protein HPBRII-4/7" EXACT [UniProtKB:Q16630] xref: EMBL:AAH00714.1 xref: EMBL:AAH05000.1 xref: EMBL:BAD97288.1 xref: EMBL:CAA47751.1 xref: EMBL:CAA47752.1 xref: UniProtKB:Q16630 xref: UniProtKB:Q53ES1 xref: UniProtKB:Q9BSJ7 xref: UniProtKB:Q9BW18 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022150 ! CPSF6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016874 ! relb-hpbrii_4 physical interaction relationship: transforms_into CCO:B0065892 ! CPSF6_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0065893 ! CPSF6_HUMAN-Phosphothreonine404 [Term] id: CCO:B0063127 name: Q96TA9_HUMAN def: "SWI related protein" [UniProtKB:Q96TA9] xref: EMBL:BAB55599.1 xref: UniProtKB:Q96TA9 is_a: CCO:U0000007 ! cell cycle protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0016881 ! relb-q96ta9 physical interaction [Term] id: CCO:B0063128 name: NQO2_HUMAN def: "Ribosyldihydronicotinamide dehydrogenase [quinone]" [UniProtKB:P16083] synonym: "EC 1.10.99.2" EXACT [UniProtKB:P16083] synonym: "NRH dehydrogenase [quinone] 2" EXACT [UniProtKB:P16083] synonym: "NRH:quinone oxidoreductase 2" EXACT [UniProtKB:P16083] synonym: "QR2" EXACT [UniProtKB:P16083] synonym: "Quinone reductase 2" EXACT [UniProtKB:P16083] xref: EMBL:AAA60239.1 xref: EMBL:AAB60642.3 xref: EMBL:AAH06096.1 xref: EMBL:AAW29945.1 xref: EMBL:BAB16974.1 xref: EMBL:CAI23294.1 xref: UniProtKB:P16083 xref: UniProtKB:Q5TD04 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022456 ! NQO2_human relationship: has_function CCO:F0000129 ! dihydronicotinamide riboside quinone reductase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002099 ! NADPH dehydrogenase (quinone) activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007988 ! coenzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0016887 ! relb-nqo2 physical interaction [Term] id: CCO:B0063129 name: HS74L_HUMAN def: "Heat shock 70 kDa protein 4L" [UniProtKB:O95757] synonym: "Heat shock 70-related protein APG-1" EXACT [UniProtKB:O95757] synonym: "Osmotic stress protein 94" EXACT [UniProtKB:O95757] xref: EMBL:AAH40560.1 xref: EMBL:AAY40975.1 xref: EMBL:BAA75063.1 xref: UniProtKB:O95757 xref: UniProtKB:Q4W5M5 xref: UniProtKB:Q8IWA2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022319 ! HSPA4L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016929 ! map3k7ip1-osp94 physical interaction relationship: transforms_into CCO:B0066921 ! HS74L_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0066922 ! HS74L_HUMAN-Phosphothreonine761 [Term] id: CCO:B0063130 name: LDHB_HUMAN def: "L-lactate dehydrogenase B chain" [UniProtKB:P07195] synonym: "EC 1.1.1.27" EXACT [UniProtKB:P07195] synonym: "LDH heart subunit" EXACT [UniProtKB:P07195] synonym: "LDH-B" EXACT [UniProtKB:P07195] synonym: "LDH-H" EXACT [UniProtKB:P07195] synonym: "Renal carcinoma antigen NY-REN-46" EXACT [UniProtKB:P07195] xref: EMBL:AAH02362.1 xref: EMBL:AAH15122.1 xref: EMBL:AAH71860.1 xref: EMBL:CAA32033.1 xref: EMBL:CAA68701.1 xref: UniProtKB:P07195 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022363 ! LDHB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0016981 ! tbk1-ldhb physical interaction relationship: transforms_into CCO:B0067606 ! LDHB_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0067607 ! LDHB_HUMAN-Phosphotyrosine240 [Term] id: CCO:B0063131 name: OST48_HUMAN def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor" [UniProtKB:P39656] synonym: "DDOST 48 kDa subunit" EXACT [UniProtKB:P39656] synonym: "EC 2.4.1.119" EXACT [UniProtKB:P39656] synonym: "Oligosaccharyl transferase 48 kDa subunit" EXACT [UniProtKB:P39656] xref: EMBL:AAH02594.1 xref: EMBL:BAA06126.1 xref: EMBL:BAA23670.1 xref: EMBL:BAB93478.1 xref: UniProtKB:O43244 xref: UniProtKB:P39656 xref: UniProtKB:Q8NI93 xref: UniProtKB:Q9BUI2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022485 ! DDOST_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017013 ! tnfrsf1a-ddost physical interaction [Term] id: CCO:B0063132 name: ERLN1_HUMAN def: "Erlin-1" [UniProtKB:O75477] synonym: "Endoplasmic reticulum lipid raft-associated protein 1" EXACT [UniProtKB:O75477] synonym: "Protein KE04" EXACT [UniProtKB:O75477] synonym: "SPFH domain-containing protein 1" EXACT [UniProtKB:O75477] synonym: "Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1" EXACT [UniProtKB:O75477] xref: EMBL:AAC26658.1 xref: EMBL:AAH31791.1 xref: EMBL:BAD96200.1 xref: EMBL:CAQ10515.1 xref: EMBL:EAW49846.1 xref: UniProtKB:B0QZ42 xref: UniProtKB:O75477 xref: UniProtKB:Q53HV0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022227 ! ERLIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017138 ! traf6-o75477 physical interaction [Term] id: CCO:B0063133 name: BRI3B_HUMAN def: "BRI3-binding protein" [UniProtKB:Q8WY22] synonym: "Cervical cancer 1 proto-oncogene-binding protein KG19" EXACT [UniProtKB:Q8WY22] synonym: "HCCR-1" EXACT [UniProtKB:Q8WY22] synonym: "I3-binding protein" EXACT [UniProtKB:Q8WY22] xref: EMBL:AAH34525.1 xref: EMBL:AAL33003.2 xref: EMBL:AAL54382.1 xref: UniProtKB:Q8WY22 xref: UniProtKB:Q8WY23 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022075 ! BRI3BP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017147 ! traf6-bri3bp physical interaction [Term] id: CCO:B0063134 name: PAPOA_HUMAN def: "Poly(A) polymerase alpha" [UniProtKB:P51003] synonym: "EC 2.7.7.19" EXACT [UniProtKB:P51003] synonym: "PAP-alpha" EXACT [UniProtKB:P51003] synonym: "Polynucleotide adenylyltransferase alpha" EXACT [UniProtKB:P51003] xref: EMBL:AAH00927.1 xref: EMBL:AAH36014.1 xref: EMBL:CAD61935.1 xref: EMBL:CAD62628.1 xref: EMBL:CAD66560.1 xref: UniProtKB:P51003 xref: UniProtKB:Q86SX4 xref: UniProtKB:Q86TV0 xref: UniProtKB:Q8IYF5 xref: UniProtKB:Q9BVU2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022490 ! PAPOLA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017157 ! rel-papola physical interaction relationship: transforms_into CCO:B0069092 ! PAPOA_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0069093 ! PAPOA_HUMAN-Phosphoserine553 [Term] id: CCO:B0063135 name: RPA49_HUMAN def: "DNA-directed RNA polymerase I subunit RPA49" [UniProtKB:Q9GZS1] synonym: "DNA-directed RNA polymerase I subunit E" EXACT [UniProtKB:Q9GZS1] synonym: "RNA polymerase I subunit A49" EXACT [UniProtKB:Q9GZS1] synonym: "RNA polymerase I-associated factor 1" EXACT [UniProtKB:Q9GZS1] synonym: "RNA polymerase I-associated factor 53" EXACT [UniProtKB:Q9GZS1] xref: EMBL:AAH01337.1 xref: EMBL:AAH14331.1 xref: EMBL:BAB14579.1 xref: EMBL:BAB14791.1 xref: EMBL:BAC03629.1 xref: EMBL:CAG33594.1 xref: EMBL:CAH73518.1 xref: EMBL:CAH73519.1 xref: UniProtKB:Q5VZT3 xref: UniProtKB:Q8NBA9 xref: UniProtKB:Q96L20 xref: UniProtKB:Q9GZS1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022598 ! POLR1E_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017176 ! nfkbib-q9gzs1 physical interaction relationship: transforms_into CCO:B0070149 ! RPA49_HUMAN-Phosphoserine225 [Term] id: CCO:B0063136 name: PDCD2_HUMAN def: "Programmed cell death protein 2" [UniProtKB:Q16342] synonym: "Zinc finger MYND domain-containing protein 7" EXACT [UniProtKB:Q16342] synonym: "Zinc finger protein Rp-8" EXACT [UniProtKB:Q16342] xref: EMBL:AAB34865.1 xref: EMBL:AAH08378.1 xref: EMBL:CAA20285.1 xref: UniProtKB:Q16342 xref: UniProtKB:Q9UH12 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022495 ! PDCD2_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017177 ! nfkbib-pdcd2 physical interaction [Term] id: CCO:B0063137 name: RPA1_HUMAN def: "DNA-directed RNA polymerase I subunit RPA1" [UniProtKB:O95602] synonym: "A190" EXACT [UniProtKB:O95602] synonym: "DNA-directed RNA polymerase I largest subunit" EXACT [UniProtKB:O95602] synonym: "DNA-directed RNA polymerase I subunit A" EXACT [UniProtKB:O95602] synonym: "EC 2.7.7.6" EXACT [UniProtKB:O95602] synonym: "RNA polymerase I 194 kDa subunit" EXACT [UniProtKB:O95602] synonym: "RNA polymerase I subunit A1" EXACT [UniProtKB:O95602] synonym: "RPA194" EXACT [UniProtKB:O95602] xref: EMBL:AAC99959.1 xref: EMBL:AAD09356.1 xref: EMBL:AAI17174.1 xref: EMBL:AAI26304.1 xref: EMBL:CAB55942.1 xref: UniProtKB:O95602 xref: UniProtKB:Q0VG05 xref: UniProtKB:Q9UEH0 xref: UniProtKB:Q9UFT9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022597 ! POLR1A_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017178 ! nfkbib-polr1a physical interaction relationship: transforms_into CCO:B0070145 ! RPA1_HUMAN-Phosphothreonine1580 [Term] id: CCO:B0063138 name: RPAB3_HUMAN def: "DNA-directed RNA polymerases I, II, and III subunit RPABC3" [UniProtKB:P52434] synonym: "DNA-directed RNA polymerase II subunit H" EXACT [UniProtKB:P52434] synonym: "DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide" EXACT [UniProtKB:P52434] synonym: "hRPB8" EXACT [UniProtKB:P52434] synonym: "RNA polymerases I, II, and III subunit ABC3" EXACT [UniProtKB:P52434] synonym: "RPB17" EXACT [UniProtKB:P52434] synonym: "RPB8" EXACT [UniProtKB:P52434] xref: EMBL:AAA91458.1 xref: EMBL:AAH00739.1 xref: EMBL:CAA89060.1 xref: EMBL:CAB92189.1 xref: UniProtKB:P52434 xref: UniProtKB:P53802 xref: UniProtKB:Q969R0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022600 ! POLR2H_human relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: participates_in CCO:I0017181 ! nfkbib-polr2h physical interaction relationship: transforms_into CCO:B0070151 ! RPAB3_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063139 name: GSLG1_HUMAN def: "Golgi apparatus protein 1 precursor" [UniProtKB:Q92896] synonym: "CFR-1" EXACT [UniProtKB:Q92896] synonym: "Cysteine-rich fibroblast growth factor receptor" EXACT [UniProtKB:Q92896] synonym: "E-selectin ligand 1" EXACT [UniProtKB:Q92896] synonym: "ESL-1" EXACT [UniProtKB:Q92896] synonym: "Golgi sialoglycoprotein MG-160" EXACT [UniProtKB:Q92896] xref: EMBL:AAB02178.1 xref: EMBL:AAB06460.1 xref: UniProtKB:Q13221 xref: UniProtKB:Q92896 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022290 ! GLG1_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0003590 ! fibroblast growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017191 ! nfkb2-glg1 physical interaction [Term] id: CCO:B0063140 name: KTN1_HUMAN def: "Kinectin" [UniProtKB:Q86UP2] synonym: "CG-1 antigen" EXACT [UniProtKB:Q86UP2] synonym: "Kinesin receptor" EXACT [UniProtKB:Q86UP2] xref: EMBL:AAB65853.1 xref: EMBL:AAH50555.1 xref: EMBL:AAP20418.1 xref: EMBL:BAA02794.2 xref: EMBL:CAA80271.1 xref: UniProtKB:Q13999 xref: UniProtKB:Q14707 xref: UniProtKB:Q15387 xref: UniProtKB:Q86UP2 xref: UniProtKB:Q86W57 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022358 ! KTN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017215 ! ikbke-ktn1 physical interaction relationship: transforms_into CCO:B0067513 ! KTN1_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0067514 ! KTN1_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0067515 ! KTN1_HUMAN-Phosphothreonine153 relationship: transforms_into CCO:B0067516 ! KTN1_HUMAN-Phosphoserine156 [Term] id: CCO:B0063141 name: Q9NWG8_HUMAN def: "cDNA FLJ10035 fis, clone HEMBA1000919" [UniProtKB:Q9NWG8] xref: EMBL:BAA91413.1 xref: UniProtKB:Q9NWG8 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017216 ! ikbkg-q9nwg8 physical interaction [Term] id: CCO:B0063142 name: PDRG1_HUMAN def: "p53 and DNA damage-regulated protein 1" [UniProtKB:Q9NUG6] xref: EMBL:AAH01856.2 xref: EMBL:AAH09334.1 xref: EMBL:AAP45329.1 xref: EMBL:CAB88101.2 xref: UniProtKB:Q96GP3 xref: UniProtKB:Q9BUW8 xref: UniProtKB:Q9NUG6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022498 ! PDRG1_human relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000777 ! prefoldin complex relationship: participates_in CCO:I0017236 ! map3k3-c20orf126 physical interaction [Term] id: CCO:B0063143 name: UBP11_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 11" [UniProtKB:P51784] synonym: "Deubiquitinating enzyme 11" EXACT [UniProtKB:P51784] synonym: "EC 3.1.2.15" EXACT [UniProtKB:P51784] synonym: "Ubiquitin thioesterase 11" EXACT [UniProtKB:P51784] synonym: "Ubiquitin-specific-processing protease 11" EXACT [UniProtKB:P51784] xref: EMBL:AAC50450.1 xref: EMBL:AAH00350.4 xref: EMBL:BAC20463.1 xref: EMBL:CAD20056.1 xref: UniProtKB:P51784 xref: UniProtKB:Q8IUG6 xref: UniProtKB:Q9BWE1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022758 ! USP11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017254 ! relb-usp11 physical interaction relationship: participates_in CCO:I0020494 ! usp11-setdb1 physical interaction relationship: participates_in CCO:I0020684 ! usp11-tbl3 physical interaction relationship: transforms_into CCO:B0071675 ! UBP11_HUMAN-Phosphoserine905 relationship: transforms_into CCO:B0071676 ! UBP11_HUMAN-Phosphoserine910 [Term] id: CCO:B0063144 name: AZI2_HUMAN def: "5-azacytidine-induced protein 2" [UniProtKB:Q9H6S1] synonym: "Nak-associated protein 1" EXACT [UniProtKB:Q9H6S1] synonym: "NF-kappa-B-activating kinase-associated protein 1" EXACT [UniProtKB:Q9H6S1] synonym: "TILP" EXACT [UniProtKB:Q9H6S1] xref: EMBL:AAF22368.1 xref: EMBL:AAF22369.1 xref: EMBL:AAH01139.1 xref: EMBL:AAH01853.1 xref: EMBL:AAO05967.1 xref: EMBL:BAB15182.1 xref: UniProtKB:Q86W99 xref: UniProtKB:Q9BQF1 xref: UniProtKB:Q9H6S1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022063 ! AZI2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017260 ! tbk1-tilp physical interaction [Term] id: CCO:B0063145 name: CTLA4_HUMAN def: "Cytotoxic T-lymphocyte protein 4 precursor" [UniProtKB:P16410] synonym: "CD152 antigen" EXACT [UniProtKB:P16410] synonym: "CTLA-4" EXACT [UniProtKB:P16410] synonym: "Cytotoxic T-lymphocyte-associated antigen 4" EXACT [UniProtKB:P16410] xref: EMBL:AAA52127.1 xref: EMBL:AAA52773.1 xref: EMBL:AAF02499.1 xref: EMBL:AAH74842.1 xref: EMBL:AAH74893.1 xref: EMBL:AAL07473.1 xref: EMBL:AAL40932.1 xref: EMBL:AAX93176.1 xref: EMBL:ABC67470.1 xref: UniProtKB:P16410 xref: UniProtKB:Q53TD5 xref: UniProtKB:Q8WXJ1 xref: UniProtKB:Q96P43 xref: UniProtKB:Q9UKN9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022160 ! CTLA4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017265 ! cd80-ctla4-1 direct interaction relationship: participates_in CCO:I0017815 ! cd86-ctla4-1 direct interaction [Term] id: CCO:B0063146 name: I10R1_HUMAN def: "Interleukin-10 receptor alpha chain precursor" [UniProtKB:Q13651] synonym: "CDw210a antigen" EXACT [UniProtKB:Q13651] synonym: "IL-10R-A" EXACT [UniProtKB:Q13651] synonym: "IL-10R1" EXACT [UniProtKB:Q13651] xref: EMBL:AAA17896.1 xref: EMBL:AAH28082.1 xref: EMBL:AAN86349.1 xref: UniProtKB:Q13651 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022325 ! IL10RA_human relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001266 ! interleukin-10 receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017266 ! il10-il10ra-1 direct interaction [Term] id: CCO:B0063147 name: HS12A_HUMAN def: "Heat shock 70 kDa protein 12A" [UniProtKB:O43301] xref: EMBL:BAA24847.1 xref: UniProtKB:O43301 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022318 ! HSPA12A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017278 ! nrcam-hspa12a-1 physical interaction relationship: participates_in CCO:I0017280 ! nrcam-hspa12a physical interaction relationship: transforms_into CCO:B0066920 ! HS12A_HUMAN-Phosphoserine23 [Term] id: CCO:B0063148 name: K1199_HUMAN def: "Protein KIAA1199 precursor" [UniProtKB:Q8WUJ3] xref: EMBL:AAG41059.1 xref: EMBL:AAH20256.1 xref: EMBL:BAA86513.1 xref: EMBL:CAB94391.1 xref: UniProtKB:Q8WUJ3 xref: UniProtKB:Q9H1K5 xref: UniProtKB:Q9NPN9 xref: UniProtKB:Q9ULM1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022345 ! KIAA1199_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017282 ! kiaa0463-kiaa1199 physical interaction [Term] id: CCO:B0063149 name: PDC6I_HUMAN def: "Programmed cell death 6-interacting protein" [UniProtKB:Q8WUM4] synonym: "ALG-2-interacting protein 1" EXACT [UniProtKB:Q8WUM4] synonym: "Hp95" EXACT [UniProtKB:Q8WUM4] synonym: "PDCD6-interacting protein" EXACT [UniProtKB:Q8WUM4] xref: EMBL:AAF08220.1 xref: EMBL:AAH20066.1 xref: EMBL:AAK20398.1 xref: EMBL:AAP36031.1 xref: EMBL:BAA92092.1 xref: EMBL:BAA92613.1 xref: UniProtKB:Q8WUM4 xref: UniProtKB:Q9BX86 xref: UniProtKB:Q9NUN0 xref: UniProtKB:Q9P2H2 xref: UniProtKB:Q9UKL5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022494 ! PDCD6IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017283 ! kiaa0463-pdcd6ip physical interaction relationship: participates_in CCO:I0020619 ! pdcd6ip-ramp3 physical interaction relationship: transforms_into CCO:B0069157 ! PDC6I_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0069158 ! PDC6I_HUMAN-Phosphoserine730 relationship: transforms_into CCO:B0069159 ! PDC6I_HUMAN-Phosphothreonine738 relationship: transforms_into CCO:B0069160 ! PDC6I_HUMAN-Phosphothreonine741 [Term] id: CCO:B0063150 name: TTC28_HUMAN def: "Tetratricopeptide repeat protein 28" [UniProtKB:Q96AY4] synonym: "TPR repeat protein 28" EXACT [UniProtKB:Q96AY4] xref: EMBL:AAH16465.1 xref: EMBL:BAA82995.3 xref: EMBL:CAB45760.2 xref: EMBL:CAB62963.1 xref: EMBL:CAB62964.1 xref: EMBL:CAB70697.1 xref: UniProtKB:O95928 xref: UniProtKB:O95929 xref: UniProtKB:Q96AY4 xref: UniProtKB:Q9NTE4 xref: UniProtKB:Q9UG31 xref: UniProtKB:Q9UGG5 xref: UniProtKB:Q9UPV8 xref: UniProtKB:Q9Y3S5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022747 ! TTC28_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017284 ! kiaa0543-kiaa1043 physical interaction relationship: transforms_into CCO:B0071615 ! TTC28_HUMAN-Phosphoserine1339 relationship: transforms_into CCO:B0071616 ! TTC28_HUMAN-Phosphoserine1343 relationship: transforms_into CCO:B0071617 ! TTC28_HUMAN-Phosphoserine1633 relationship: transforms_into CCO:B0071618 ! TTC28_HUMAN-Phosphoserine1706 [Term] id: CCO:B0063151 name: AT7L1_HUMAN def: "Ataxin-7-like protein 1" [UniProtKB:Q9ULK2] synonym: "Ataxin-7-like protein 4" EXACT [UniProtKB:Q9ULK2] xref: EMBL:AAH30616.1 xref: EMBL:BAA86532.1 xref: UniProtKB:Q8N2T0 xref: UniProtKB:Q9ULK2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022055 ! ATXN7L1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017285 ! kiaa0543-kiaa1218 physical interaction [Term] id: CCO:B0063152 name: THS7A_HUMAN def: "Thrombospondin type-1 domain-containing protein 7A precursor" [UniProtKB:Q9UPZ6] xref: EMBL:BAA76804.2 xref: UniProtKB:Q9UPZ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022713 ! THSD7A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017290 ! kiaa0960-ddef2 physical interaction relationship: transforms_into CCO:B0071386 ! THS7A_HUMAN-Phosphotyrosine1341 [Term] id: CCO:B0063153 name: E41L3_HUMAN def: "Band 4.1-like protein 3" [UniProtKB:Q9Y2J2] synonym: "4.1B" EXACT [UniProtKB:Q9Y2J2] synonym: "DAL-1" EXACT [UniProtKB:Q9Y2J2] synonym: "Differentially expressed in adenocarcinoma of the lung protein 1" EXACT [UniProtKB:Q9Y2J2] xref: EMBL:AAC79806.1 xref: EMBL:AAH06141.1 xref: EMBL:BAA76831.1 xref: UniProtKB:O95713 xref: UniProtKB:Q9BRP5 xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022204 ! EPB41L3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017291 ! epb41l3-kiaa1032 physical interaction relationship: transforms_into CCO:B0065960 ! E41L3_HUMAN-Phosphoserine88 relationship: transforms_into CCO:B0065961 ! E41L3_HUMAN-Phosphoserine443 relationship: transforms_into CCO:B0065962 ! E41L3_HUMAN-Phosphoserine460 relationship: transforms_into CCO:B0065963 ! E41L3_HUMAN-Phosphothreonine462 relationship: transforms_into CCO:B0065964 ! E41L3_HUMAN-Phosphothreonine469 relationship: transforms_into CCO:B0065965 ! E41L3_HUMAN-Phosphothreonine703 relationship: transforms_into CCO:B0065966 ! E41L3_HUMAN-Phosphothreonine704 relationship: transforms_into CCO:B0065967 ! E41L3_HUMAN-Phosphoserine708 relationship: transforms_into CCO:B0065968 ! E41L3_HUMAN-Phosphoserine762 relationship: transforms_into CCO:B0065969 ! E41L3_HUMAN-Phosphothreonine784 relationship: transforms_into CCO:B0065970 ! E41L3_HUMAN-Phosphoserine787 relationship: transforms_into CCO:B0065971 ! E41L3_HUMAN-Phosphoserine788 relationship: transforms_into CCO:B0065972 ! E41L3_HUMAN-Phosphoserine962 relationship: transforms_into CCO:B0065973 ! E41L3_HUMAN-Phosphothreonine1081 [Term] id: CCO:B0063154 name: BTBD3_HUMAN def: "BTB/POZ domain-containing protein 3" [UniProtKB:Q9Y2F9] xref: EMBL:BAA76796.2 xref: EMBL:CAC22147.1 xref: UniProtKB:Q9Y2F9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022076 ! BTBD3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017295 ! kiaa1206-btbd3 physical interaction [Term] id: CCO:B0063155 name: WDTC1_HUMAN def: "WD and tetratricopeptide repeats protein 1" [UniProtKB:Q8N5D0] xref: EMBL:AAH32523.1 xref: EMBL:BAA82989.1 xref: EMBL:BAA91868.1 xref: UniProtKB:Q8N5D0 xref: UniProtKB:Q9NV87 xref: UniProtKB:Q9UPW4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022786 ! WDTC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017298 ! crsp3-wdtc1 physical interaction [Term] id: CCO:B0063156 name: SRBS2_HUMAN def: "Sorbin and SH3 domain-containing protein 2" [UniProtKB:O94875] synonym: "Arg/Abl-interacting protein 2" EXACT [UniProtKB:O94875] synonym: "ArgBP2" EXACT [UniProtKB:O94875] synonym: "Sorbin" EXACT [UniProtKB:O94875] xref: EMBL:AAC05508.1 xref: EMBL:AAC05509.1 xref: EMBL:AAH11883.1 xref: EMBL:BAA34497.2 xref: EMBL:EAX04630.1 xref: EMBL:EAX04631.1 xref: UniProtKB:A6NEK9 xref: UniProtKB:O60592 xref: UniProtKB:O60593 xref: UniProtKB:O94875 xref: UniProtKB:Q96EX0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0008430 ! SORBS2_human relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000934 ! Z disc relationship: participates_in CCO:I0017300 ! sema6a-kiaa0777 physical interaction relationship: transforms_into CCO:B0070871 ! SRBS2_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0070872 ! SRBS2_HUMAN-Phosphoserine259 relationship: transforms_into CCO:B0070873 ! SRBS2_HUMAN-Phosphothreonine277 relationship: transforms_into CCO:B0070874 ! SRBS2_HUMAN-Phosphoserine278 relationship: transforms_into CCO:B0070875 ! SRBS2_HUMAN-Phosphoserine298 relationship: transforms_into CCO:B0070876 ! SRBS2_HUMAN-Phosphoserine299 relationship: transforms_into CCO:B0070877 ! SRBS2_HUMAN-Phosphoserine301 relationship: transforms_into CCO:B0070878 ! SRBS2_HUMAN-Phosphoserine302 relationship: transforms_into CCO:B0070879 ! SRBS2_HUMAN-Phosphothreonine371 relationship: transforms_into CCO:B0070880 ! SRBS2_HUMAN-Phosphoserine376 relationship: transforms_into CCO:B0070881 ! SRBS2_HUMAN-Phosphoserine750 relationship: transforms_into CCO:B0070882 ! SRBS2_HUMAN-Phosphoserine1017 relationship: transforms_into CCO:B0070883 ! SRBS2_HUMAN-Phosphoserine1018 [Term] id: CCO:B0063157 name: LSM4_HUMAN def: "U6 snRNA-associated Sm-like protein LSm4" [UniProtKB:Q9Y4Z0] synonym: "Glycine-rich protein" EXACT [UniProtKB:Q9Y4Z0] synonym: "GRP" EXACT [UniProtKB:Q9Y4Z0] xref: EMBL:AAD56228.1 xref: EMBL:AAF17216.1 xref: EMBL:AAF90055.1 xref: EMBL:AAH00387.1 xref: EMBL:AAH03652.1 xref: EMBL:AAH22198.1 xref: EMBL:AAH23665.1 xref: EMBL:CAB45867.1 xref: UniProtKB:Q9Y4Z0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022379 ! LSM4_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000290 ! snRNP U6 relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: participates_in CCO:I0017321 ! lsm4-nmi physical interaction relationship: participates_in CCO:I0017322 ! lsm4-pepp2 physical interaction relationship: transforms_into CCO:B0067788 ! LSM4_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0063158 name: IF6_HUMAN def: "Eukaryotic translation initiation factor 6" [UniProtKB:P56537] synonym: "B(2)GCN homolog" EXACT [UniProtKB:P56537] synonym: "B4 integrin interactor" EXACT [UniProtKB:P56537] synonym: "CAB" EXACT [UniProtKB:P56537] synonym: "eIF-6" EXACT [UniProtKB:P56537] synonym: "p27(BBP)" EXACT [UniProtKB:P56537] xref: EMBL:AAB97735.1 xref: EMBL:AAC39897.1 xref: EMBL:AAH01119.1 xref: EMBL:AAH11845.1 xref: EMBL:AAH19305.1 xref: EMBL:BAB93472.1 xref: EMBL:CAA72243.1 xref: EMBL:CAC17101.1 xref: UniProtKB:P56537 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022334 ! EIF6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017330 ! xrn2-itgb4bp physical interaction relationship: transforms_into CCO:B0067053 ! IF6_HUMAN-Phosphotyrosine113 relationship: transforms_into CCO:B0067054 ! IF6_HUMAN-Phosphoserine174 relationship: transforms_into CCO:B0067055 ! IF6_HUMAN-Phosphoserine175 relationship: transforms_into CCO:B0067056 ! IF6_HUMAN-Phosphoserine239 relationship: transforms_into CCO:B0067057 ! IF6_HUMAN-Phosphoserine243 [Term] id: CCO:B0063159 name: PARPT_HUMAN def: "TCDD-inducible poly [ADP-ribose] polymerase" [UniProtKB:Q7Z3E1] synonym: "EC 2.4.2.30" EXACT [UniProtKB:Q7Z3E1] synonym: "PARP-7" EXACT [UniProtKB:Q7Z3E1] synonym: "Poly [ADP-ribose] polymerase 7" EXACT [UniProtKB:Q7Z3E1] xref: EMBL:AAH50350.2 xref: EMBL:CAB45747.2 xref: EMBL:CAD97929.1 xref: EMBL:CAH18441.1 xref: UniProtKB:Q68CY9 xref: UniProtKB:Q7Z3E1 xref: UniProtKB:Q86VP4 xref: UniProtKB:Q9Y4P7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022491 ! TIPARP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017332 ! xrn2-dkfzp686n0351 physical interaction [Term] id: CCO:B0063160 name: COMT_HUMAN def: "Catechol O-methyltransferase" [UniProtKB:P21964] synonym: "EC 2.1.1.6" EXACT [UniProtKB:P21964] xref: EMBL:AAA68927.1 xref: EMBL:AAA68928.1 xref: EMBL:AAA68929.1 xref: EMBL:AAH11935.1 xref: EMBL:AAI00019.1 xref: EMBL:AAP88929.1 xref: EMBL:BAF83129.1 xref: EMBL:CAA81263.1 xref: EMBL:CAG30308.1 xref: EMBL:CAG33278.1 xref: EMBL:EAX03010.1 xref: UniProtKB:P21964 xref: UniProtKB:Q6IB07 xref: UniProtKB:Q6ICE6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022146 ! COMT_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001758 ! O-methyltransferase activity relationship: has_function CCO:F0003066 ! catechol O-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017333 ! xrn2-comt physical interaction relationship: participates_in CCO:I0020582 ! litaf-comt physical interaction relationship: transforms_into CCO:B0065890 ! COMT_HUMAN-Phosphoserine267 [Term] id: CCO:B0063161 name: MOCS3_HUMAN def: "Molybdenum cofactor synthesis protein 3" [UniProtKB:O95396] synonym: "EC 6.-.-.-" EXACT [UniProtKB:O95396] synonym: "Molybdopterin synthase sulfurylase" EXACT [UniProtKB:O95396] synonym: "MPT synthase sulfurylase" EXACT [UniProtKB:O95396] xref: EMBL:AAC72412.1 xref: EMBL:AAH15939.1 xref: EMBL:CAB53750.1 xref: UniProtKB:O95396 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022403 ! MOCS3_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017334 ! xrn2-mocs3 physical interaction [Term] id: CCO:B0063162 name: TADBP_HUMAN def: "TAR DNA-binding protein 43" [UniProtKB:Q13148] synonym: "TDP-43" EXACT [UniProtKB:Q13148] xref: EMBL:AAA70033.1 xref: EMBL:AAH71657.1 xref: EMBL:AAH95435.1 xref: EMBL:CAB43367.1 xref: EMBL:CAG38565.1 xref: EMBL:CAI22098.1 xref: UniProtKB:Q13148 xref: UniProtKB:Q6FI92 xref: UniProtKB:Q96DJ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022701 ! TARDBP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0017336 ! xrn2-tardbp physical interaction relationship: participates_in CCO:I0019846 ! tardbp-setdb1 physical interaction relationship: participates_in CCO:I0019847 ! tardbp-zhx1 physical interaction relationship: transforms_into CCO:B0071082 ! TADBP_HUMAN-Phosphoserine91 relationship: transforms_into CCO:B0071083 ! TADBP_HUMAN-Phosphoserine92 [Term] id: CCO:B0063163 name: ZN330_HUMAN def: "Zinc finger protein 330" [UniProtKB:Q9Y3S2] synonym: "Nucleolar autoantigen 36" EXACT [UniProtKB:Q9Y3S2] synonym: "Nucleolar cysteine-rich protein" EXACT [UniProtKB:Q9Y3S2] xref: EMBL:AAH04421.1 xref: EMBL:CAB43112.1 xref: EMBL:CAC18679.1 xref: UniProtKB:Q9Y3S2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022807 ! ZNF330_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0001017 ! midbody relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: participates_in CCO:I0017342 ! znf408-noa36 physical interaction relationship: transforms_into CCO:B0072110 ! ZN330_HUMAN-Phosphotyrosine308 relationship: transforms_into CCO:B0072111 ! ZN330_HUMAN-Phosphotyrosine315 [Term] id: CCO:B0063164 name: CC136_HUMAN def: "Coiled-coil domain-containing protein 136" [UniProtKB:Q96JN2] synonym: "Nasopharyngeal carcinoma-associated gene 6 protein" EXACT [UniProtKB:Q96JN2] xref: EMBL:AAI50332.1 xref: EMBL:AAI52409.1 xref: EMBL:BAB14590.1 xref: EMBL:BAB47422.1 xref: EMBL:BAC85854.1 xref: EMBL:CAB61359.1 xref: EMBL:EAL24111.1 xref: EMBL:EAW83682.1 xref: EMBL:EAW83684.1 xref: UniProtKB:A4D1K1 xref: UniProtKB:A7MCY7 xref: UniProtKB:A8MYA7 xref: UniProtKB:Q6ZVK7 xref: UniProtKB:Q96JN2 xref: UniProtKB:Q9H8M3 xref: UniProtKB:Q9UFE1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022098 ! CCDC136_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017343 ! znf408-kiaa1793 physical interaction [Term] id: CCO:B0063165 name: RPB11_HUMAN def: "DNA-directed RNA polymerase II subunit RPB11-a" [UniProtKB:P52435] synonym: "DNA-directed RNA polymerase II 13.3 kDa polypeptide" EXACT [UniProtKB:P52435] synonym: "DNA-directed RNA polymerase II subunit J-1" EXACT [UniProtKB:P52435] synonym: "RNA polymerase II subunit B11-a" EXACT [UniProtKB:P52435] synonym: "RPB11a" EXACT [UniProtKB:P52435] xref: EMBL:AAD05361.1 xref: EMBL:AAH24165.1 xref: EMBL:AAH65711.1 xref: EMBL:CAA57785.1 xref: EMBL:CAA67075.1 xref: UniProtKB:O43375 xref: UniProtKB:P52435 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022602 ! POLR2J_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction [Term] id: CCO:B0063166 name: RPB7_HUMAN def: "DNA-directed RNA polymerase II subunit RPB7" [UniProtKB:P62487] synonym: "DNA-directed RNA polymerase II 19 kDa polypeptide" EXACT [UniProtKB:P62487] synonym: "DNA-directed RNA polymerase II subunit G" EXACT [UniProtKB:P62487] synonym: "RNA polymerase II subunit B7" EXACT [UniProtKB:P62487] xref: EMBL:AAA86500.1 xref: EMBL:AAB96827.1 xref: EMBL:AAI12163.1 xref: EMBL:AAI12165.1 xref: UniProtKB:P52433 xref: UniProtKB:P62487 xref: UniProtKB:Q2M1Z4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022604 ! POLR2G_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction [Term] id: CCO:B0063167 name: RPAB1_HUMAN def: "DNA-directed RNA polymerases I, II, and III subunit RPABC1" [UniProtKB:P19388] synonym: "DNA-directed RNA polymerase II 23 kDa polypeptide" EXACT [UniProtKB:P19388] synonym: "DNA-directed RNA polymerase II subunit E" EXACT [UniProtKB:P19388] synonym: "RNA polymerases I, II, and III subunit ABC1" EXACT [UniProtKB:P19388] synonym: "RPB5" EXACT [UniProtKB:P19388] synonym: "XAP4" EXACT [UniProtKB:P19388] xref: EMBL:AAA62401.1 xref: EMBL:AAB19339.1 xref: EMBL:AAC03238.1 xref: EMBL:AAH04441.1 xref: EMBL:AAH34144.1 xref: EMBL:BAA07406.1 xref: UniProtKB:O43380 xref: UniProtKB:P19388 xref: UniProtKB:Q6PIH5 xref: UniProtKB:Q9BT06 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022599 ! POLR2E_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction [Term] id: CCO:B0063168 name: RPB2_HUMAN def: "DNA-directed RNA polymerase II subunit RPB2" [UniProtKB:P30876] synonym: "DNA-directed RNA polymerase II 140 kDa polypeptide" EXACT [UniProtKB:P30876] synonym: "DNA-directed RNA polymerase II subunit B" EXACT [UniProtKB:P30876] synonym: "EC 2.7.7.6" EXACT [UniProtKB:P30876] synonym: "RNA polymerase II subunit 2" EXACT [UniProtKB:P30876] synonym: "RNA polymerase II subunit B2" EXACT [UniProtKB:P30876] xref: EMBL:AAC09367.1 xref: EMBL:AAH23503.2 xref: EMBL:CAA45124.1 xref: UniProtKB:P30876 xref: UniProtKB:Q8IZ61 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022603 ! POLR2B_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: participates_in CCO:I0006505 ! q9btt4-q71f56-1 physical interaction relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction [Term] id: CCO:B0063169 name: SR140_HUMAN def: "U2-associated protein SR140" [UniProtKB:O15042] synonym: "140 kDa Ser/Arg-rich domain protein" EXACT [UniProtKB:O15042] xref: EMBL:AAH06474.1 xref: EMBL:AAH16323.1 xref: EMBL:AAI05605.1 xref: EMBL:AAI11693.1 xref: EMBL:BAA20790.1 xref: EMBL:DAA00075.1 xref: UniProtKB:A0PJ60 xref: UniProtKB:O15042 xref: UniProtKB:Q0D2M1 xref: UniProtKB:Q2NKQ7 xref: UniProtKB:Q9BR70 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022676 ! SR140_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: transforms_into CCO:B0070858 ! SR140_HUMAN-Phosphoserine811 relationship: transforms_into CCO:B0070859 ! SR140_HUMAN-Phosphoserine946 relationship: transforms_into CCO:B0070860 ! SR140_HUMAN-Phosphoserine948 [Term] id: CCO:B0063170 name: DCD_HUMAN def: "Dermcidin precursor" [UniProtKB:P81605] synonym: "Preproteolysin" EXACT [UniProtKB:P81605] xref: EMBL:AAH62682.1 xref: EMBL:AAH69108.1 xref: EMBL:AAK94785.1 xref: EMBL:AAL18349.1 xref: EMBL:AAL25801.1 xref: UniProtKB:P58461 xref: UniProtKB:P81605 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022171 ! DCD_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction [Term] id: CCO:B0063171 name: DDX52_HUMAN def: "Probable ATP-dependent RNA helicase DDX52" [UniProtKB:Q9Y2R4] synonym: "ATP-dependent RNA helicase ROK1-like" EXACT [UniProtKB:Q9Y2R4] synonym: "DEAD box protein 52" EXACT [UniProtKB:Q9Y2R4] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9Y2R4] xref: EMBL:AAD27766.1 xref: EMBL:AAH41785.1 xref: EMBL:BAA91812.1 xref: EMBL:BAC04214.1 xref: EMBL:CAA09374.1 xref: UniProtKB:Q86YG1 xref: UniProtKB:Q8N213 xref: UniProtKB:Q9NVE0 xref: UniProtKB:Q9Y2R4 xref: UniProtKB:Q9Y482 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022179 ! DDX52_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006506 ! q9nwa0-q71f56-1 physical interaction relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: transforms_into CCO:B0065941 ! DDX52_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0065942 ! DDX52_HUMAN-Phosphoserine99 [Term] id: CCO:B0063172 name: CC026_HUMAN def: "Uncharacterized protein C3orf26" [UniProtKB:Q9BQ75] xref: EMBL:AAH06475.1 xref: EMBL:AAH06512.1 xref: EMBL:BAF84081.1 xref: EMBL:BAG35386.1 xref: UniProtKB:A8K5S7 xref: UniProtKB:Q9BQ75 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022094 ! C3orf26_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction [Term] id: CCO:B0063173 name: UC5IP_HUMAN def: "UCHL5-interacting protein" [UniProtKB:Q99871] synonym: "26S proteasome-associated UCH37-interacting protein 1" EXACT [UniProtKB:Q99871] synonym: "X-linked protein STS1769" EXACT [UniProtKB:Q99871] xref: EMBL:AAF75785.1 xref: EMBL:AAH08141.3 xref: EMBL:CAA67665.1 xref: UniProtKB:Q96HS8 xref: UniProtKB:Q99871 xref: UniProtKB:Q9NP54 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022764 ! UCHL5IP_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: transforms_into CCO:B0071709 ! UC5IP_HUMAN-Phosphoserine16 [Term] id: CCO:B0063174 name: IDLC_HUMAN def: "Axonemal dynein light intermediate polypeptide 1" [UniProtKB:O14645] synonym: "hp28" EXACT [UniProtKB:O14645] synonym: "Inner dynein arm light chain, axonemal" EXACT [UniProtKB:O14645] xref: EMBL:AAB69193.1 xref: EMBL:AAH39074.1 xref: EMBL:AAH46117.1 xref: EMBL:CAI20553.1 xref: UniProtKB:O14645 xref: UniProtKB:Q05BL9 xref: UniProtKB:Q5TGH0 xref: UniProtKB:Q7L0I5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022331 ! DNALI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction relationship: participates_in CCO:I0020305 ! eps8-dnali1 physical interaction [Term] id: CCO:B0063175 name: DIMT1_HUMAN def: "Probable dimethyladenosine transferase" [UniProtKB:Q9UNQ2] synonym: "18S rRNA dimethylase" EXACT [UniProtKB:Q9UNQ2] synonym: "DIM1 dimethyladenosine transferase 1-like" EXACT [UniProtKB:Q9UNQ2] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q9UNQ2] synonym: "S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase" EXACT [UniProtKB:Q9UNQ2] xref: EMBL:AAC72947.1 xref: EMBL:AAC97955.1 xref: EMBL:AAH02841.1 xref: EMBL:AAH10874.1 xref: EMBL:CAA08815.1 xref: UniProtKB:O76025 xref: UniProtKB:Q9BU77 xref: UniProtKB:Q9UES1 xref: UniProtKB:Q9UNQ2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022189 ! DIMT1L_human relationship: has_function CCO:F0000035 ! rRNA (adenine-N6,N6-)-dimethyltransferase activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0002014 ! rRNA methyltransferase activity relationship: has_function CCO:F0003155 ! rRNA (adenine) methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0006507 ! q9nx70-q71f56-1 physical interaction [Term] id: CCO:B0063176 name: DDX50_HUMAN def: "ATP-dependent RNA helicase DDX50" [UniProtKB:Q9BQ39] synonym: "DEAD box protein 50" EXACT [UniProtKB:Q9BQ39] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9BQ39] synonym: "Gu-beta" EXACT [UniProtKB:Q9BQ39] synonym: "Nucleolar protein Gu2" EXACT [UniProtKB:Q9BQ39] xref: EMBL:AAH00210.1 xref: EMBL:AAH00272.1 xref: EMBL:AAH18637.2 xref: EMBL:AAK29402.1 xref: UniProtKB:Q8WV76 xref: UniProtKB:Q9BQ39 xref: UniProtKB:Q9BWI8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022178 ! DDX50_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006508 ! crsp7-q71f56-1 physical interaction relationship: transforms_into CCO:B0065939 ! DDX50_HUMAN-Phosphoserine45 relationship: transforms_into CCO:B0065940 ! DDX50_HUMAN-Phosphoserine82 [Term] id: CCO:B0063177 name: UBA1_HUMAN def: "Ubiquitin-like modifier-activating enzyme 1" [UniProtKB:P22314] synonym: "Protein A1S9" EXACT [UniProtKB:P22314] synonym: "Ubiquitin-activating enzyme E1" EXACT [UniProtKB:P22314] xref: EMBL:AAA61246.1 xref: EMBL:AAH13041.1 xref: EMBL:CAA37078.1 xref: EMBL:CAA40296.1 xref: EMBL:CAI41708.1 xref: EMBL:EAW59290.1 xref: UniProtKB:P22314 xref: UniProtKB:Q5JRR8 xref: UniProtKB:Q96E13 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022754 ! UBA1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002013 ! small protein activating enzyme activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0017590 ! ube1-taf9 physical interaction relationship: transforms_into CCO:B0071664 ! UBA1_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0071665 ! UBA1_HUMAN-Phosphotyrosine55 [Term] id: CCO:B0063178 name: ALDOA_HUMAN def: "Fructose-bisphosphate aldolase A" [UniProtKB:P04075] synonym: "EC 4.1.2.13" EXACT [UniProtKB:P04075] synonym: "Lung cancer antigen NY-LU-1" EXACT [UniProtKB:P04075] synonym: "Muscle-type aldolase" EXACT [UniProtKB:P04075] xref: EMBL:AAA51690.1 xref: EMBL:AAA51697.1 xref: EMBL:AAH00367.2 xref: EMBL:AAH04333.1 xref: EMBL:AAH10660.1 xref: EMBL:AAH12880.1 xref: EMBL:AAH13614.1 xref: EMBL:AAH15888.1 xref: EMBL:AAH16170.1 xref: EMBL:AAH16800.1 xref: EMBL:CAA28861.1 xref: EMBL:CAA30979.1 xref: EMBL:CAG46678.1 xref: UniProtKB:P04075 xref: UniProtKB:Q6FH76 xref: UniProtKB:Q96B15 xref: UniProtKB:Q9BWD9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022033 ! ALDOA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: transforms_into CCO:B0065592 ! ALDOA_HUMAN-Phosphotyrosine3 relationship: transforms_into CCO:B0065593 ! ALDOA_HUMAN-Phosphotyrosine5 relationship: transforms_into CCO:B0065594 ! ALDOA_HUMAN-N6-acetyllysine13 relationship: transforms_into CCO:B0065595 ! ALDOA_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0065596 ! ALDOA_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0065597 ! ALDOA_HUMAN-N6-acetyllysine42 relationship: transforms_into CCO:B0065598 ! ALDOA_HUMAN-Phosphoserine46 relationship: transforms_into CCO:B0065599 ! ALDOA_HUMAN-Phosphothreonine65 relationship: transforms_into CCO:B0065600 ! ALDOA_HUMAN-Phosphotyrosine204 relationship: transforms_into CCO:B0065601 ! ALDOA_HUMAN-Phosphotyrosine223 relationship: transforms_into CCO:B0065602 ! ALDOA_HUMAN-Phosphothreonine235 relationship: transforms_into CCO:B0065603 ! ALDOA_HUMAN-Phosphothreonine241 relationship: transforms_into CCO:B0065604 ! ALDOA_HUMAN-Phosphoserine354 relationship: transforms_into CCO:B0065605 ! ALDOA_HUMAN-Phosphoserine356 [Term] id: CCO:B0063179 name: LDHA_HUMAN def: "L-lactate dehydrogenase A chain" [UniProtKB:P00338] synonym: "Cell proliferation-inducing gene 19 protein" EXACT [UniProtKB:P00338] synonym: "EC 1.1.1.27" EXACT [UniProtKB:P00338] synonym: "LDH muscle subunit" EXACT [UniProtKB:P00338] synonym: "LDH-A" EXACT [UniProtKB:P00338] synonym: "LDH-M" EXACT [UniProtKB:P00338] synonym: "Renal carcinoma antigen NY-REN-59" EXACT [UniProtKB:P00338] xref: EMBL:AAB20418.1 xref: EMBL:AAH67223.1 xref: EMBL:AAS00490.1 xref: EMBL:BAC85389.1 xref: EMBL:BAD96798.1 xref: EMBL:CAA26088.1 xref: EMBL:CAA26879.1 xref: EMBL:CAG33056.1 xref: EMBL:CAG46515.1 xref: UniProtKB:P00338 xref: UniProtKB:Q53G53 xref: UniProtKB:Q6IBM7 xref: UniProtKB:Q6ZNV1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022362 ! LDHA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: transforms_into CCO:B0067604 ! LDHA_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0067605 ! LDHA_HUMAN-Phosphotyrosine239 [Term] id: CCO:B0063180 name: SERC_HUMAN def: "Phosphoserine aminotransferase" [UniProtKB:Q9Y617] synonym: "EC 2.6.1.52" EXACT [UniProtKB:Q9Y617] synonym: "Phosphohydroxythreonine aminotransferase" EXACT [UniProtKB:Q9Y617] synonym: "PSAT" EXACT [UniProtKB:Q9Y617] xref: EMBL:AAD42052.1 xref: EMBL:AAH00971.1 xref: EMBL:AAH04863.1 xref: EMBL:AAH16645.1 xref: EMBL:AAH18129.1 xref: EMBL:AAP35486.1 xref: UniProtKB:Q96AW2 xref: UniProtKB:Q9BQ12 xref: UniProtKB:Q9Y617 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022641 ! PSAT1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001021 ! phosphoserine transaminase activity relationship: has_function CCO:F0001944 ! transaminase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction [Term] id: CCO:B0063181 name: MDHC_HUMAN def: "Malate dehydrogenase, cytoplasmic" [UniProtKB:P40925] synonym: "Cytosolic malate dehydrogenase" EXACT [UniProtKB:P40925] synonym: "EC 1.1.1.37" EXACT [UniProtKB:P40925] xref: EMBL:AAC16436.1 xref: EMBL:AAH01484.1 xref: EMBL:AAY14893.1 xref: EMBL:BAA09513.1 xref: EMBL:CAG33686.1 xref: UniProtKB:P40925 xref: UniProtKB:Q6I9V0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022392 ! MDH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0020372 ! mpp3-mdh1 physical interaction relationship: transforms_into CCO:B0068110 ! MDHC_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0068111 ! MDHC_HUMAN-Phosphotyrosine210 [Term] id: CCO:B0063182 name: EF2_HUMAN def: "Elongation factor 2" [UniProtKB:P13639] synonym: "EF-2" EXACT [UniProtKB:P13639] xref: EMBL:AAA50388.1 xref: EMBL:AAI26260.1 xref: EMBL:AAX34409.1 xref: EMBL:CAA35829.1 xref: EMBL:CAA77750.1 xref: UniProtKB:P13639 xref: UniProtKB:Q58J86 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022213 ! EEF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0065981 ! EF2_HUMAN-Phosphothreonine54 relationship: transforms_into CCO:B0065982 ! EF2_HUMAN-Phosphothreonine57 relationship: transforms_into CCO:B0065983 ! EF2_HUMAN-Phosphothreonine59 relationship: transforms_into CCO:B0065984 ! EF2_HUMAN-Phosphotyrosine265 relationship: transforms_into CCO:B0065985 ! EF2_HUMAN-Phosphoserine502 relationship: transforms_into CCO:B0065986 ! EF2_HUMAN-Diphthamide715 [Term] id: CCO:B0063183 name: RL5_HUMAN def: "60S ribosomal protein L5" [UniProtKB:P46777] xref: EMBL:AAA85654.1 xref: EMBL:AAB18361.1 xref: EMBL:AAG39281.1 xref: EMBL:BAD96324.1 xref: EMBL:CAI22505.1 xref: UniProtKB:P46777 xref: UniProtKB:Q53HH6 xref: UniProtKB:Q9H3F4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022581 ! RPL5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: transforms_into CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 [Term] id: CCO:B0063184 name: MYG1_HUMAN def: "UPF0160 protein MYG1" [UniProtKB:Q9HB07] xref: EMBL:AAG17847.1 xref: UniProtKB:Q9HB07 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022415 ! C12orf10_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction [Term] id: CCO:B0063185 name: SYAC_HUMAN def: "Alanyl-tRNA synthetase, cytoplasmic" [UniProtKB:P49588] synonym: "Alanine--tRNA ligase" EXACT [UniProtKB:P49588] synonym: "AlaRS" EXACT [UniProtKB:P49588] synonym: "EC 6.1.1.7" EXACT [UniProtKB:P49588] synonym: "Renal carcinoma antigen NY-REN-42" EXACT [UniProtKB:P49588] xref: EMBL:AAH11451.1 xref: EMBL:BAA06808.1 xref: EMBL:BAD96544.1 xref: EMBL:EAW51839.1 xref: UniProtKB:A6NF14 xref: UniProtKB:P49588 xref: UniProtKB:Q53GV7 xref: UniProtKB:Q96FA0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022688 ! AARS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction relationship: transforms_into CCO:B0071020 ! SYAC_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0071021 ! SYAC_HUMAN-Phosphoserine555 relationship: transforms_into CCO:B0071022 ! SYAC_HUMAN-Phosphothreonine578 relationship: transforms_into CCO:B0071023 ! SYAC_HUMAN-Phosphotyrosine580 [Term] id: CCO:B0063186 name: SIAS_HUMAN def: "Sialic acid synthase" [UniProtKB:Q9NR45] synonym: "EC 2.5.1.56" EXACT [UniProtKB:Q9NR45] synonym: "EC 2.5.1.57" EXACT [UniProtKB:Q9NR45] synonym: "N-acetylneuraminate synthase" EXACT [UniProtKB:Q9NR45] synonym: "N-acetylneuraminate-9-phosphate synthase" EXACT [UniProtKB:Q9NR45] synonym: "N-acetylneuraminic acid phosphate synthase" EXACT [UniProtKB:Q9NR45] synonym: "N-acetylneuraminic acid synthase" EXACT [UniProtKB:Q9NR45] xref: EMBL:AAF75261.1 xref: EMBL:AAH00008.1 xref: EMBL:AAH19315.1 xref: EMBL:BAA91818.1 xref: EMBL:CAI13886.1 xref: UniProtKB:Q8WUV9 xref: UniProtKB:Q9BWS6 xref: UniProtKB:Q9NR45 xref: UniProtKB:Q9NVD4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022654 ! NANS_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0002126 ! N-acylneuraminate cytidylyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006752 ! N-acylneuraminate-9-phosphate synthase activity relationship: has_function CCO:F0007806 ! N-acetylneuraminate synthase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006537 ! hspcb-aars physical interaction [Term] id: CCO:B0063187 name: DDX23_HUMAN def: "Probable ATP-dependent RNA helicase DDX23" [UniProtKB:Q9BUQ8] synonym: "100 kDa U5 snRNP-specific protein" EXACT [UniProtKB:Q9BUQ8] synonym: "DEAD box protein 23" EXACT [UniProtKB:Q9BUQ8] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9BUQ8] synonym: "PRP28 homolog" EXACT [UniProtKB:Q9BUQ8] synonym: "U5-100kD" EXACT [UniProtKB:Q9BUQ8] xref: EMBL:AAB87902.1 xref: EMBL:AAH02366.1 xref: UniProtKB:O43188 xref: UniProtKB:Q9BUQ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022176 ! DDX23_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: transforms_into CCO:B0065935 ! DDX23_HUMAN-Phosphoserine14 relationship: transforms_into CCO:B0065936 ! DDX23_HUMAN-Phosphothreonine25 relationship: transforms_into CCO:B0065937 ! DDX23_HUMAN-Phosphoserine107 relationship: transforms_into CCO:B0065938 ! DDX23_HUMAN-Phosphoserine109 [Term] id: CCO:B0063188 name: H12_HUMAN def: "Histone H1.2" [UniProtKB:P16403] synonym: "Histone H1d" EXACT [UniProtKB:P16403] xref: EMBL:AAH02649.1 xref: EMBL:AAN06700.1 xref: EMBL:CAA40408.1 xref: UniProtKB:P16403 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022292 ! HIST1H1C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: transforms_into CCO:B0066675 ! H12_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066676 ! H12_HUMAN-Phosphothreonine31 relationship: transforms_into CCO:B0066677 ! H12_HUMAN-Phosphoserine36 relationship: transforms_into CCO:B0066678 ! H12_HUMAN-Phosphoserine173 [Term] id: CCO:B0063189 name: RU2A_HUMAN def: "U2 small nuclear ribonucleoprotein A'" [UniProtKB:P09661] synonym: "U2 snRNP-A'" EXACT [UniProtKB:P09661] xref: EMBL:AAH22816.1 xref: EMBL:AAH71717.1 xref: EMBL:CAA31838.1 xref: UniProtKB:P09661 xref: UniProtKB:Q8TBD2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022620 ! SNRPA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0007786 ! top1-2 physical interaction relationship: transforms_into CCO:B0070268 ! RU2A_HUMAN-Phosphoserine197 [Term] id: CCO:B0063190 name: H1X_HUMAN def: "Histone H1x" [UniProtKB:Q92522] xref: EMBL:AAH00426.1 xref: EMBL:AAH10435.1 xref: EMBL:BAA11018.1 xref: UniProtKB:Q92522 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022293 ! H1FX_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006548 ! top1-npm1 physical interaction relationship: participates_in CCO:I0006549 ! top1-hnrpc physical interaction relationship: transforms_into CCO:B0066679 ! H1X_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066680 ! H1X_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0066681 ! H1X_HUMAN-Phosphoserine31 [Term] id: CCO:B0063191 name: GREM1_HUMAN def: "Gremlin-1 precursor" [UniProtKB:O60565] synonym: "Cell proliferation-inducing gene 2 protein" EXACT [UniProtKB:O60565] synonym: "Cysteine knot superfamily 1, BMP antagonist 1" EXACT [UniProtKB:O60565] synonym: "DAN domain family member 2" EXACT [UniProtKB:O60565] synonym: "Down-regulated in Mos-transformed cells protein" EXACT [UniProtKB:O60565] synonym: "IHG-2" EXACT [UniProtKB:O60565] synonym: "Increased in high glucose protein 2" EXACT [UniProtKB:O60565] xref: EMBL:AAC39725.1 xref: EMBL:AAF06677.1 xref: EMBL:AAG23891.1 xref: EMBL:AAH69525.1 xref: EMBL:AAH93778.1 xref: EMBL:AAI01612.1 xref: EMBL:AAP69985.1 xref: EMBL:BAA84462.1 xref: EMBL:BAC04620.1 xref: EMBL:BAC04643.1 xref: UniProtKB:O60565 xref: UniProtKB:Q52LV3 xref: UniProtKB:Q8N914 xref: UniProtKB:Q8N936 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022289 ! GREM1_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0017393 ! grem1-14_3_3 eta-1 direct interaction relationship: participates_in CCO:I0017394 ! 14_3_3 eta-grem1 direct interaction relationship: participates_in CCO:I0018873 ! grem1-14_3_3 eta physical interaction relationship: participates_in CCO:I0019514 ! grem1-14_3_3 eta-2 physical interaction relationship: participates_in CCO:I0019515 ! 14_3_3 eta-grem1-1 physical interaction [Term] id: CCO:B0063192 name: TRPC3_HUMAN def: "Short transient receptor potential channel 3" [UniProtKB:Q13507] synonym: "hTrp-3" EXACT [UniProtKB:Q13507] synonym: "hTrp3" EXACT [UniProtKB:Q13507] synonym: "Transient receptor protein 3" EXACT [UniProtKB:Q13507] synonym: "TRP-3" EXACT [UniProtKB:Q13507] synonym: "TrpC3" EXACT [UniProtKB:Q13507] xref: EMBL:AAC51653.1 xref: EMBL:AAH93682.1 xref: EMBL:AAH93684.1 xref: EMBL:CAA61448.1 xref: EMBL:CAA74083.1 xref: UniProtKB:O00593 xref: UniProtKB:Q13507 xref: UniProtKB:Q15660 xref: UniProtKB:Q52M35 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022740 ! TRPC3_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002736 ! store-operated calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017402 ! mx1-trpc3-2 physical interaction relationship: participates_in CCO:I0019450 ! mx1-trpc3-1 physical interaction [Term] id: CCO:B0063193 name: FA48A_HUMAN def: "Protein FAM48A" [UniProtKB:Q8NEM7] synonym: "p38-interacting protein" EXACT [UniProtKB:Q8NEM7] synonym: "p38IP" EXACT [UniProtKB:Q8NEM7] xref: EMBL:AAD40550.1 xref: EMBL:AAH30686.1 xref: EMBL:AAQ15220.1 xref: EMBL:CAB62207.1 xref: EMBL:CAI14005.1 xref: EMBL:CAI15193.1 xref: UniProtKB:Q71RF3 xref: UniProtKB:Q8NEM7 xref: UniProtKB:Q9Y6A6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022246 ! FAM48A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017404 ! fam48a-mapk14 physical interaction relationship: participates_in CCO:I0019034 ! atxn1-fam48a physical interaction relationship: participates_in CCO:I0019299 ! fam48a-mapk14-1 physical interaction relationship: participates_in CCO:I0019300 ! fam48a-mapk14-2 physical interaction [Term] id: CCO:B0063194 name: MOFA1_HUMAN def: "MORF4 family-associated protein 1" [UniProtKB:Q9Y605] synonym: "Protein associated with MRG of 14 kDa" EXACT [UniProtKB:Q9Y605] synonym: "Protein PGR1" EXACT [UniProtKB:Q9Y605] xref: EMBL:AAD38498.1 xref: EMBL:AAH22797.1 xref: EMBL:CAG33425.1 xref: UniProtKB:Q9Y605 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022404 ! MRFAP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017413 ! morf4l2-mrfap1-1 physical interaction [Term] id: CCO:B0063195 name: SYHC_HUMAN def: "Histidyl-tRNA synthetase, cytoplasmic" [UniProtKB:P12081] synonym: "EC 6.1.1.21" EXACT [UniProtKB:P12081] synonym: "HisRS" EXACT [UniProtKB:P12081] synonym: "Histidine--tRNA ligase" EXACT [UniProtKB:P12081] xref: EMBL:AAA58668.1 xref: EMBL:AAA73973.1 xref: EMBL:AAH11807.1 xref: EMBL:AAH80514.1 xref: EMBL:CAA28956.1 xref: EMBL:CAA77607.1 xref: UniProtKB:P12081 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022690 ! HARS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001179 ! histidine-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017432 ! tnik-hars physical interaction [Term] id: CCO:B0063196 name: TRIM2_HUMAN def: "Tripartite motif-containing protein 2" [UniProtKB:Q9C040] synonym: "RING finger protein 86" EXACT [UniProtKB:Q9C040] xref: EMBL:AAG53472.1 xref: EMBL:AAH05016.1 xref: EMBL:AAH11052.1 xref: EMBL:BAA25443.1 xref: EMBL:CAB53687.2 xref: UniProtKB:O60272 xref: UniProtKB:Q9BSI9 xref: UniProtKB:Q9C040 xref: UniProtKB:Q9UFZ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022737 ! TRIM2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017468 ! tnik-trim2 physical interaction [Term] id: CCO:B0063197 name: MUC13_HUMAN def: "Mucin-13 precursor" [UniProtKB:Q9H3R2] synonym: "Down-regulated in colon cancer 1" EXACT [UniProtKB:Q9H3R2] synonym: "MUC-13" EXACT [UniProtKB:Q9H3R2] xref: EMBL:AAK56861.1 xref: EMBL:AAQ89190.1 xref: EMBL:BAA90925.1 xref: EMBL:BAB19651.1 xref: UniProtKB:Q6UWD9 xref: UniProtKB:Q9H3R2 xref: UniProtKB:Q9NXT5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022412 ! MUC13_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction [Term] id: CCO:B0063198 name: SORL_HUMAN def: "Sortilin-related receptor precursor" [UniProtKB:Q92673] synonym: "LDLR relative with 11 ligand-binding repeats" EXACT [UniProtKB:Q92673] synonym: "Low-density lipoprotein receptor relative with 11 ligand-binding repeats" EXACT [UniProtKB:Q92673] synonym: "LR11" EXACT [UniProtKB:Q92673] synonym: "SorLA" EXACT [UniProtKB:Q92673] synonym: "SorLA-1" EXACT [UniProtKB:Q92673] synonym: "Sorting protein-related receptor containing LDLR class A repeats" EXACT [UniProtKB:Q92673] xref: EMBL:AAC50891.2 xref: EMBL:CAA69325.1 xref: UniProtKB:Q92673 xref: UniProtKB:Q92856 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022668 ! SORL1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0004336 ! low-density lipoprotein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction [Term] id: CCO:B0063199 name: REPS1_HUMAN def: "RalBP1-associated Eps domain-containing protein 1" [UniProtKB:Q96D71] synonym: "RalBP1-interacting protein 1" EXACT [UniProtKB:Q96D71] xref: EMBL:AAH12764.1 xref: EMBL:AAH21211.1 xref: EMBL:AAK34942.1 xref: EMBL:CAD38569.1 xref: EMBL:CAI42877.1 xref: UniProtKB:Q5JWJ7 xref: UniProtKB:Q8NDR7 xref: UniProtKB:Q8WU62 xref: UniProtKB:Q96D71 xref: UniProtKB:Q9BXY9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022564 ! REPS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0069860 ! REPS1_HUMAN-Phosphoserine66 relationship: transforms_into CCO:B0069861 ! REPS1_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0069862 ! REPS1_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0069863 ! REPS1_HUMAN-Phosphoserine118 relationship: transforms_into CCO:B0069864 ! REPS1_HUMAN-Phosphothreonine121 relationship: transforms_into CCO:B0069865 ! REPS1_HUMAN-Phosphoserine122 relationship: transforms_into CCO:B0069866 ! REPS1_HUMAN-Phosphoserine220 relationship: transforms_into CCO:B0069867 ! REPS1_HUMAN-Phosphotyrosine236 relationship: transforms_into CCO:B0069868 ! REPS1_HUMAN-Phosphoserine255 relationship: transforms_into CCO:B0069869 ! REPS1_HUMAN-Phosphoserine437 relationship: transforms_into CCO:B0069870 ! REPS1_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0069871 ! REPS1_HUMAN-Phosphoserine657 relationship: transforms_into CCO:B0069872 ! REPS1_HUMAN-Phosphoserine699 [Term] id: CCO:B0063200 name: SH3L2_HUMAN def: "SH3 domain-binding glutamic acid-rich-like protein 2" [UniProtKB:Q9UJC5] synonym: "Fovea-associated SH3 domain-binding protein" EXACT [UniProtKB:Q9UJC5] xref: EMBL:AAK37526.1 xref: EMBL:CAB55867.2 xref: EMBL:CAC35771.1 xref: UniProtKB:Q9BPY5 xref: UniProtKB:Q9UJC5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022651 ! SH3BGRL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction [Term] id: CCO:B0063201 name: EPN4_HUMAN def: "Clathrin interactor 1" [UniProtKB:Q14677] synonym: "Clathrin-interacting protein localized in the trans-Golgi region" EXACT [UniProtKB:Q14677] synonym: "Clint" EXACT [UniProtKB:Q14677] synonym: "Enthoprotin" EXACT [UniProtKB:Q14677] synonym: "Epsin-4" EXACT [UniProtKB:Q14677] synonym: "Epsin-related protein" EXACT [UniProtKB:Q14677] synonym: "EpsinR" EXACT [UniProtKB:Q14677] xref: EMBL:AAH04467.1 xref: EMBL:AAH13091.1 xref: EMBL:AAL30768.1 xref: EMBL:BAA11488.2 xref: EMBL:BAC03971.1 xref: EMBL:DAA00062.1 xref: UniProtKB:Q14677 xref: UniProtKB:Q8NAF1 xref: UniProtKB:Q96E05 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022223 ! CLINT1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0066016 ! EPN4_HUMAN-Phosphoserine22 relationship: transforms_into CCO:B0066017 ! EPN4_HUMAN-Phosphoserine26 relationship: transforms_into CCO:B0066018 ! EPN4_HUMAN-Phosphoserine163 relationship: transforms_into CCO:B0066019 ! EPN4_HUMAN-Phosphoserine227 relationship: transforms_into CCO:B0066020 ! EPN4_HUMAN-Phosphoserine232 relationship: transforms_into CCO:B0066021 ! EPN4_HUMAN-Phosphoserine234 relationship: transforms_into CCO:B0066022 ! EPN4_HUMAN-Phosphoserine245 relationship: transforms_into CCO:B0066023 ! EPN4_HUMAN-Phosphothreonine272 relationship: transforms_into CCO:B0066024 ! EPN4_HUMAN-Phosphoserine299 [Term] id: CCO:B0063202 name: ATD3A_HUMAN def: "ATPase family AAA domain-containing protein 3A" [UniProtKB:Q9NVI7] xref: EMBL:AAH07803.1 xref: EMBL:AAH11814.1 xref: EMBL:AAH14101.1 xref: EMBL:AAH33109.1 xref: EMBL:AAH63607.1 xref: EMBL:BAA91764.1 xref: EMBL:BAC03595.1 xref: EMBL:CAI22954.1 xref: EMBL:CAI22955.1 xref: UniProtKB:Q5SV23 xref: UniProtKB:Q8N275 xref: UniProtKB:Q96A50 xref: UniProtKB:Q9NVI7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022057 ! ATAD3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0065756 ! ATD3A_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0065757 ! ATD3A_HUMAN-N6-acetyllysine539 [Term] id: CCO:B0063203 name: AT2A3_HUMAN def: "Sarcoplasmic/endoplasmic reticulum calcium ATPase 3" [UniProtKB:Q93084] synonym: "Calcium pump 3" EXACT [UniProtKB:Q93084] synonym: "EC 3.6.3.8" EXACT [UniProtKB:Q93084] synonym: "SERCA3" EXACT [UniProtKB:Q93084] synonym: "SR Ca(2+)-ATPase 3" EXACT [UniProtKB:Q93084] xref: EMBL:AAB29700.1 xref: EMBL:AAC24525.1 xref: EMBL:AAC24526.1 xref: EMBL:AAH35729.1 xref: EMBL:AAL78967.1 xref: EMBL:AAL78968.1 xref: EMBL:CAA75739.1 xref: EMBL:CAA75747.1 xref: EMBL:CAA75748.1 xref: EMBL:CAA93736.1 xref: EMBL:CAA93737.1 xref: UniProtKB:O60900 xref: UniProtKB:O60901 xref: UniProtKB:O75501 xref: UniProtKB:O75502 xref: UniProtKB:Q16115 xref: UniProtKB:Q8TEX5 xref: UniProtKB:Q8TEX6 xref: UniProtKB:Q93084 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022054 ! ATP2A3_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001602 ! calcium-transporting ATPase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000802 ! sarcoplasmic reticulum relationship: located_in CCO:C0001358 ! nuclear membrane relationship: located_in CCO:C0001507 ! sarcoplasmic reticulum membrane relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0065755 ! AT2A3_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0063204 name: AP1B1_HUMAN def: "AP-1 complex subunit beta-1" [UniProtKB:Q10567] synonym: "Adapter-related protein complex 1 subunit beta-1" EXACT [UniProtKB:Q10567] synonym: "Adaptor protein complex AP-1 subunit beta-1" EXACT [UniProtKB:Q10567] synonym: "Beta-adaptin 1" EXACT [UniProtKB:Q10567] synonym: "Beta1-adaptin" EXACT [UniProtKB:Q10567] synonym: "Clathrin assembly protein complex 1 beta large chain" EXACT [UniProtKB:Q10567] synonym: "Golgi adaptor HA1/AP1 adaptin beta subunit" EXACT [UniProtKB:Q10567] xref: EMBL:AAC50684.2 xref: EMBL:AAC98702.1 xref: UniProtKB:P78436 xref: UniProtKB:Q10567 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022036 ! AP1B1_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0065656 ! AP1B1_HUMAN-Phosphotyrosine897 [Term] id: CCO:B0063205 name: TACD1_HUMAN def: "Tumor-associated calcium signal transducer 1 precursor" [UniProtKB:P16422] synonym: "Adenocarcinoma-associated antigen" EXACT [UniProtKB:P16422] synonym: "CD326 antigen" EXACT [UniProtKB:P16422] synonym: "Cell surface glycoprotein Trop-1" EXACT [UniProtKB:P16422] synonym: "EGP" EXACT [UniProtKB:P16422] synonym: "Epithelial cell surface antigen" EXACT [UniProtKB:P16422] synonym: "Epithelial glycoprotein" EXACT [UniProtKB:P16422] synonym: "KS 1/4 antigen" EXACT [UniProtKB:P16422] synonym: "KSA" EXACT [UniProtKB:P16422] synonym: "Major gastrointestinal tumor-associated protein GA733-2" EXACT [UniProtKB:P16422] xref: EMBL:AAA35723.1 xref: EMBL:AAA35861.1 xref: EMBL:AAA36151.1 xref: EMBL:AAA59543.1 xref: EMBL:AAB00775.1 xref: EMBL:AAH14785.1 xref: EMBL:AAY15095.1 xref: EMBL:CAA32870.1 xref: EMBL:CAG47055.1 xref: EMBL:CAG47078.1 xref: EMBL:EAX00218.1 xref: UniProtKB:P16422 xref: UniProtKB:P18180 xref: UniProtKB:Q6FG26 xref: UniProtKB:Q6FG49 xref: UniProtKB:Q96C47 xref: UniProtKB:Q9UCD0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022700 ! TACSTD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017488 ! cftr-asha1 physical interaction relationship: transforms_into CCO:B0071080 ! TACD1_HUMAN-Pyrrolidone carboxylic acid24 [Term] id: CCO:B0063206 name: HSP77_HUMAN def: "Putative heat shock 70 kDa protein 7" [UniProtKB:P48741] synonym: "Heat shock 70 kDa protein B" EXACT [UniProtKB:P48741] xref: EMBL:AAA52696.1 xref: UniProtKB:P19790 xref: UniProtKB:P48741 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004837 ! HSPA7_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction [Term] id: CCO:B0063207 name: CYTB_HUMAN def: "Cystatin-B" [UniProtKB:P04080] synonym: "CPI-B" EXACT [UniProtKB:P04080] synonym: "Liver thiol proteinase inhibitor" EXACT [UniProtKB:P04080] synonym: "Stefin-B" EXACT [UniProtKB:P04080] xref: EMBL:AAA35727.1 xref: EMBL:AAA99014.1 xref: EMBL:AAF44059.1 xref: EMBL:AAH03370.1 xref: EMBL:AAH10532.1 xref: EMBL:BAA95541.1 xref: UniProtKB:P04080 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022167 ! CSTB_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: transforms_into CCO:B0065922 ! CYTB_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0063208 name: SNX4_HUMAN def: "Sorting nexin-4" [UniProtKB:O95219] xref: EMBL:AAC83149.1 xref: EMBL:AAH18762.1 xref: UniProtKB:O95219 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022667 ! SNX4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction [Term] id: CCO:B0063209 name: CALU_HUMAN def: "Calumenin precursor" [UniProtKB:O43852] synonym: "Crocalbin" EXACT [UniProtKB:O43852] synonym: "IEF SSP 9302" EXACT [UniProtKB:O43852] xref: EMBL:AAB97725.1 xref: EMBL:AAC17216.1 xref: EMBL:AAF76141.1 xref: EMBL:AAH13383.1 xref: EMBL:AAK72908.1 xref: EMBL:CAG46634.1 xref: UniProtKB:O43852 xref: UniProtKB:O60456 xref: UniProtKB:Q6FHB9 xref: UniProtKB:Q96RL3 xref: UniProtKB:Q9NR43 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022084 ! CALU_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: transforms_into CCO:B0065811 ! CALU_HUMAN-Phosphoserine44 relationship: transforms_into CCO:B0065812 ! CALU_HUMAN-Phosphothreonine65 [Term] id: CCO:B0063210 name: RCN1_HUMAN def: "Reticulocalbin-1 precursor" [UniProtKB:Q15293] xref: EMBL:AAH10120.1 xref: EMBL:BAA07670.1 xref: UniProtKB:Q15293 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022561 ! RCN1_human relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0018958 ! atxn1-rcn1 physical interaction relationship: participates_in CCO:I0018980 ! atxn1-rcn1-1 physical interaction relationship: participates_in CCO:I0019080 ! atxn1-rcn1-2 physical interaction [Term] id: CCO:B0063211 name: SQRD_HUMAN def: "Sulfide:quinone oxidoreductase, mitochondrial precursor" [UniProtKB:Q9Y6N5] synonym: "EC 1.-.-.-" EXACT [UniProtKB:Q9Y6N5] xref: EMBL:AAD34039.1 xref: EMBL:AAD41160.1 xref: EMBL:AAH16836.1 xref: UniProtKB:Q9UQM8 xref: UniProtKB:Q9Y6N5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022675 ! SQRDL_human relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: participates_in CCO:I0006606 ! cftr-ebp-1 physical interaction relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction [Term] id: CCO:B0063212 name: SPTA1_HUMAN def: "Spectrin alpha chain, erythrocyte" [UniProtKB:P02549] synonym: "Erythroid alpha-spectrin" EXACT [UniProtKB:P02549] xref: EMBL:AAA53103.1 xref: EMBL:AAA60569.1 xref: EMBL:AAA60575.1 xref: EMBL:AAA60577.1 xref: EMBL:AAA60994.1 xref: UniProtKB:P02549 xref: UniProtKB:Q15514 xref: UniProtKB:Q6LDY5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022672 ! SPTA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017489 ! spta1-sptb2-1 direct interaction relationship: participates_in CCO:I0018139 ! abi1-spta1-2 physical interaction relationship: participates_in CCO:I0019197 ! spta1-sptb2-2 direct interaction relationship: participates_in CCO:I0019198 ! spta1-sptb2-3 direct interaction relationship: participates_in CCO:I0019199 ! spta1-sptb1-1 direct interaction relationship: participates_in CCO:I0019226 ! abi1-spta1-1 physical interaction [Term] id: CCO:B0063213 name: HCD2_HUMAN def: "3-hydroxyacyl-CoA dehydrogenase type-2" [UniProtKB:Q99714] synonym: "3-hydroxy-2-methylbutyryl-CoA dehydrogenase" EXACT [UniProtKB:Q99714] synonym: "3-hydroxyacyl-CoA dehydrogenase type II" EXACT [UniProtKB:Q99714] synonym: "EC 1.1.1.178" EXACT [UniProtKB:Q99714] synonym: "EC 1.1.1.35" EXACT [UniProtKB:Q99714] synonym: "Endoplasmic reticulum-associated amyloid beta-peptide-binding protein" EXACT [UniProtKB:Q99714] synonym: "Short-chain type dehydrogenase/reductase XH98G2" EXACT [UniProtKB:Q99714] synonym: "Type II HADH" EXACT [UniProtKB:Q99714] xref: EMBL:AAB68958.1 xref: EMBL:AAC15902.1 xref: EMBL:AAC16419.1 xref: EMBL:AAC39900.1 xref: EMBL:AAC51812.1 xref: EMBL:AAH00372.1 xref: EMBL:AAH08708.1 xref: EMBL:AAM18189.1 xref: UniProtKB:Q8TCV9 xref: UniProtKB:Q96HD5 xref: UniProtKB:Q99714 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022302 ! HSD17B10_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000376 ! 3-hydroxyacyl-CoA dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002064 ! 7-alpha-hydroxysteroid dehydrogenase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006328 ! 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0017493 ! app-hadh2-1 physical interaction relationship: participates_in CCO:I0017644 ! hadh2-app-2 physical interaction relationship: participates_in CCO:I0018136 ! app-hadh2-2 physical interaction relationship: participates_in CCO:I0018569 ! hadh2-app-1 physical interaction relationship: transforms_into CCO:B0066766 ! HCD2_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063214 name: VA0D1_HUMAN def: "V-type proton ATPase subunit d 1" [UniProtKB:P61421] synonym: "32 kDa accessory protein" EXACT [UniProtKB:P61421] synonym: "P39" EXACT [UniProtKB:P61421] synonym: "V-ATPase 40 kDa accessory protein" EXACT [UniProtKB:P61421] synonym: "V-ATPase AC39 subunit" EXACT [UniProtKB:P61421] synonym: "V-ATPase subunit d 1" EXACT [UniProtKB:P61421] synonym: "Vacuolar proton pump subunit d 1" EXACT [UniProtKB:P61421] xref: EMBL:AAC15852.1 xref: EMBL:AAH08861.1 xref: EMBL:CAA50591.1 xref: UniProtKB:P12953 xref: UniProtKB:P61421 xref: UniProtKB:Q02547 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022770 ! ATP6V0D1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017553 ! atp6v0d1-atxn1 physical interaction relationship: transforms_into CCO:B0071772 ! VA0D1_HUMAN-Phosphotyrosine270 relationship: transforms_into CCO:B0071773 ! VA0D1_HUMAN-Phosphoserine283 [Term] id: CCO:B0063215 name: FA46A_HUMAN def: "Protein FAM46A" [UniProtKB:Q96IP4] synonym: "HBV X-transactivated gene 11 protein" EXACT [UniProtKB:Q96IP4] xref: EMBL:AAH00683.1 xref: EMBL:AAH07351.1 xref: EMBL:AAM53071.1 xref: EMBL:AAW66943.1 xref: EMBL:BAA90903.1 xref: EMBL:BAF84798.1 xref: EMBL:CAI23544.1 xref: EMBL:CAI23545.1 xref: EMBL:EAW48692.1 xref: UniProtKB:A8K7U4 xref: UniProtKB:Q5TF86 xref: UniProtKB:Q8NFZ9 xref: UniProtKB:Q96IP4 xref: UniProtKB:Q9BW32 xref: UniProtKB:Q9NXV5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022244 ! FAM46A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017558 ! fam46a-atxn1 physical interaction [Term] id: CCO:B0063216 name: ZC3HA_HUMAN def: "Zinc finger CCCH domain-containing protein 10" [UniProtKB:Q96K80] xref: EMBL:AAH18708.1 xref: EMBL:BAB55059.1 xref: UniProtKB:Q96K80 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022797 ! ZC3H10_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017560 ! zc3h10-atxn1 physical interaction relationship: participates_in CCO:I0018992 ! atxn1-zc3h10 physical interaction relationship: participates_in CCO:I0019036 ! atxn1-zc3h10-1 physical interaction [Term] id: CCO:B0063217 name: M11D1_HUMAN def: "Protein RSM22 homolog, mitochondrial precursor" [UniProtKB:Q9H7H0] synonym: "EC 2.1.1.-" EXACT [UniProtKB:Q9H7H0] synonym: "False p73 target gene protein" EXACT [UniProtKB:Q9H7H0] synonym: "Methyltransferase 11 domain-containing protein 1" EXACT [UniProtKB:Q9H7H0] xref: EMBL:AAH05053.1 xref: EMBL:AAK08200.1 xref: EMBL:AAK08201.1 xref: EMBL:BAB14919.1 xref: EMBL:EAW66433.1 xref: EMBL:EAW66434.1 xref: UniProtKB:Q9BSH1 xref: UniProtKB:Q9BZH2 xref: UniProtKB:Q9BZH3 xref: UniProtKB:Q9H7H0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022383 ! METT11D1_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0017561 ! q9h7h0-atxn1 physical interaction relationship: participates_in CCO:I0018952 ! atxn1-q9h7h0 physical interaction relationship: participates_in CCO:I0018972 ! atxn1-q9h7h0-1 physical interaction relationship: participates_in CCO:I0019076 ! atxn1-q9h7h0-2 physical interaction relationship: participates_in CCO:I0019094 ! atxn1-q9h7h0-3 physical interaction [Term] id: CCO:B0063218 name: ZCH13_HUMAN def: "Zinc finger CCHC domain-containing protein 13" [UniProtKB:Q8WW36] xref: EMBL:AAH21176.1 xref: UniProtKB:Q8WW36 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022798 ! ZCCHC13_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017569 ! zcchc13-atxn1 physical interaction [Term] id: CCO:B0063219 name: RN138_HUMAN def: "E3 ubiquitin-protein ligase RNF138" [UniProtKB:Q8WVD3] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q8WVD3] synonym: "Nemo-like kinase-associated RING finger protein" EXACT [UniProtKB:Q8WVD3] synonym: "NLK-associated RING finger protein" EXACT [UniProtKB:Q8WVD3] synonym: "RING finger protein 138" EXACT [UniProtKB:Q8WVD3] xref: EMBL:AAD46623.2 xref: EMBL:AAH18107.1 xref: EMBL:AAP35524.1 xref: EMBL:BAB14614.1 xref: EMBL:CAB63712.1 xref: EMBL:CAG33431.1 xref: UniProtKB:Q8WVD3 xref: UniProtKB:Q9H8K2 xref: UniProtKB:Q9UF87 xref: UniProtKB:Q9UKI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022589 ! RNF138_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0017587 ! rnf138-taf9 physical interaction relationship: transforms_into CCO:B0070100 ! RN138_HUMAN-Phosphoserine124 [Term] id: CCO:B0063220 name: IDH3B_HUMAN def: "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor" [UniProtKB:O43837] synonym: "EC 1.1.1.41" EXACT [UniProtKB:O43837] synonym: "Isocitric dehydrogenase" EXACT [UniProtKB:O43837] synonym: "NAD(+)-specific ICDH" EXACT [UniProtKB:O43837] xref: EMBL:AAB94295.1 xref: EMBL:AAD09339.1 xref: EMBL:AAD09340.1 xref: EMBL:AAH01960.1 xref: EMBL:CAB43266.1 xref: EMBL:CAC01442.2 xref: EMBL:CAC01443.1 xref: UniProtKB:O43837 xref: UniProtKB:O95106 xref: UniProtKB:Q5JXS8 xref: UniProtKB:Q9NQ06 xref: UniProtKB:Q9NQ07 xref: UniProtKB:Q9UEX0 xref: UniProtKB:Q9UG99 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022330 ! IDH3B_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000849 ! isocitrate dehydrogenase (NAD+) activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0017612 ! atxn2-idh3b physical interaction relationship: participates_in CCO:I0020575 ! hrmt1l2-idh3b physical interaction relationship: participates_in CCO:I0020643 ! rab35-idh3b physical interaction [Term] id: CCO:B0063221 name: AT7L2_HUMAN def: "Ataxin-7-like protein 2" [UniProtKB:Q5T6C5] xref: EMBL:CAI22937.1 xref: UniProtKB:Q5T6C5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022056 ! ATXN7L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017616 ! atxn7l2-mdfi physical interaction relationship: participates_in CCO:I0019126 ! atxn7l2-cbx3 physical interaction relationship: participates_in CCO:I0019127 ! atxn7l2-lamb1 physical interaction [Term] id: CCO:B0063222 name: OSTA_HUMAN def: "Organic solute transporter subunit alpha" [UniProtKB:Q86UW1] synonym: "OST-alpha" EXACT [UniProtKB:Q86UW1] xref: EMBL:AAP23993.1 xref: EMBL:BAD18802.1 xref: EMBL:EAW53665.1 xref: UniProtKB:Q6ZMC7 xref: UniProtKB:Q86UW1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022486 ! OSTA_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017628 ! atxn1-q86uw1-1 physical interaction [Term] id: CCO:B0063223 name: Q8N6V2_HUMAN def: "UBASH3A protein" [UniProtKB:Q8N6V2] xref: EMBL:AAH28138.1 xref: UniProtKB:Q8N6V2 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction [Term] id: CCO:B0063224 name: INSL6_HUMAN def: "Insulin-like peptide INSL6 precursor" [UniProtKB:Q9Y581] synonym: "Insulin-like peptide 6" EXACT [UniProtKB:Q9Y581] synonym: "Relaxin/insulin-like factor 1" EXACT [UniProtKB:Q9Y581] xref: EMBL:AAD39003.1 xref: EMBL:AAF29604.1 xref: EMBL:AAI26474.1 xref: EMBL:AAI26476.1 xref: EMBL:CAD13336.1 xref: UniProtKB:A0AVS0 xref: UniProtKB:Q9NS16 xref: UniProtKB:Q9Y581 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022339 ! INSL6_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction [Term] id: CCO:B0063225 name: LMNB1_HUMAN def: "Lamin-B1" [UniProtKB:P20700] xref: EMBL:AAA36162.1 xref: EMBL:AAC37575.1 xref: EMBL:AAH12295.1 xref: EMBL:AAI03724.1 xref: UniProtKB:P20700 xref: UniProtKB:Q3SYN7 xref: UniProtKB:Q96EI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022374 ! LMNB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: transforms_into CCO:B0067718 ! LMNB1_HUMAN-Phosphoserine13 relationship: transforms_into CCO:B0067719 ! LMNB1_HUMAN-Phosphothreonine19 relationship: transforms_into CCO:B0067720 ! LMNB1_HUMAN-Phosphothreonine20 relationship: transforms_into CCO:B0067721 ! LMNB1_HUMAN-Phosphoserine23 relationship: transforms_into CCO:B0067722 ! LMNB1_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0067723 ! LMNB1_HUMAN-Phosphoserine200 relationship: transforms_into CCO:B0067724 ! LMNB1_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0067725 ! LMNB1_HUMAN-Phosphoserine393 relationship: transforms_into CCO:B0067726 ! LMNB1_HUMAN-Phosphoserine404 relationship: transforms_into CCO:B0067727 ! LMNB1_HUMAN-Phosphothreonine575 [Term] id: CCO:B0063226 name: FN3K_HUMAN def: "Fructosamine-3-kinase" [UniProtKB:Q9H479] synonym: "EC 2.7.1.-" EXACT [UniProtKB:Q9H479] xref: EMBL:AAH42680.1 xref: EMBL:CAC16393.1 xref: UniProtKB:Q9H479 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022259 ! FN3K_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction relationship: transforms_into CCO:B0066228 ! FN3K_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0066229 ! FN3K_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0066230 ! FN3K_HUMAN-Phosphotyrosine263 [Term] id: CCO:B0063227 name: MEP1B_HUMAN def: "Meprin A subunit beta precursor" [UniProtKB:Q16820] synonym: "EC 3.4.24.18" EXACT [UniProtKB:Q16820] synonym: "Endopeptidase-2" EXACT [UniProtKB:Q16820] synonym: "N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta" EXACT [UniProtKB:Q16820] synonym: "PABA peptide hydrolase" EXACT [UniProtKB:Q16820] synonym: "PPH beta" EXACT [UniProtKB:Q16820] xref: EMBL:AAU05377.1 xref: EMBL:CAA57107.1 xref: UniProtKB:Q16820 xref: UniProtKB:Q670J1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022396 ! MEP1B_human relationship: has_function CCO:F0000686 ! meprin A activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001983 ! astacin activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0006664 ! npm_alk-gak physical interaction [Term] id: CCO:B0063228 name: CD22_HUMAN def: "B-cell receptor CD22 precursor" [UniProtKB:P20273] synonym: "B-lymphocyte cell adhesion molecule" EXACT [UniProtKB:P20273] synonym: "BL-CAM" EXACT [UniProtKB:P20273] synonym: "CD22 antigen" EXACT [UniProtKB:P20273] synonym: "Leu-14" EXACT [UniProtKB:P20273] synonym: "Sialic acid-binding Ig-like lectin 2" EXACT [UniProtKB:P20273] synonym: "Siglec-2" EXACT [UniProtKB:P20273] xref: EMBL:AAB06448.1 xref: EMBL:AAB06449.1 xref: EMBL:BAA36564.1 xref: EMBL:BAA36565.1 xref: EMBL:BAA36566.1 xref: EMBL:BAA36567.1 xref: EMBL:BAA36568.1 xref: EMBL:BAA36569.1 xref: EMBL:BAA36571.1 xref: EMBL:BAA36572.1 xref: EMBL:BAA36573.1 xref: EMBL:BAA36575.1 xref: EMBL:CAA36988.1 xref: EMBL:CAA42006.1 xref: UniProtKB:O95699 xref: UniProtKB:O95701 xref: UniProtKB:O95702 xref: UniProtKB:O95703 xref: UniProtKB:P20273 xref: UniProtKB:Q01665 xref: UniProtKB:Q92872 xref: UniProtKB:Q92873 xref: UniProtKB:Q9UQA6 xref: UniProtKB:Q9UQA7 xref: UniProtKB:Q9UQA8 xref: UniProtKB:Q9UQA9 xref: UniProtKB:Q9UQB0 xref: UniProtKB:Q9Y2A6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022108 ! CD22_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017641 ! cd22-lyn-1 physical interaction relationship: participates_in CCO:I0017642 ! lyn-cd22-1 physical interaction relationship: participates_in CCO:I0017861 ! cd22-ptpn6-2 physical interaction relationship: participates_in CCO:I0017897 ! cd22-ptpn6-1 physical interaction relationship: participates_in CCO:I0017898 ! ptpn6-cd22-1 physical interaction relationship: participates_in CCO:I0017904 ! ptpn-6-cd22-2 physical interaction relationship: participates_in CCO:I0017905 ! cd22-ksyk-1 physical interaction relationship: participates_in CCO:I0017906 ! cd22-plcg1 physical interaction relationship: transforms_into CCO:B0065843 ! CD22_HUMAN-Phosphotyrosine762 relationship: transforms_into CCO:B0065844 ! CD22_HUMAN-Phosphotyrosine807 relationship: transforms_into CCO:B0065845 ! CD22_HUMAN-Phosphotyrosine822 relationship: transforms_into CCO:B0065846 ! CD22_HUMAN-Phosphotyrosine842 [Term] id: CCO:B0063229 name: SCRB1_HUMAN def: "Scavenger receptor class B member 1" [UniProtKB:Q8WTV0] synonym: "CD36 and LIMPII analogous 1" EXACT [UniProtKB:Q8WTV0] synonym: "CD36 antigen" EXACT [UniProtKB:Q8WTV0] synonym: "CD36 antigen-like 1" EXACT [UniProtKB:Q8WTV0] synonym: "CLA-1" EXACT [UniProtKB:Q8WTV0] synonym: "Collagen type I receptor, thrombospondin receptor-like 1" EXACT [UniProtKB:Q8WTV0] synonym: "SR-BI" EXACT [UniProtKB:Q8WTV0] synonym: "SRB1" EXACT [UniProtKB:Q8WTV0] xref: EMBL:AAH80647.1 xref: EMBL:AAQ08185.1 xref: EMBL:CAA80277.1 xref: UniProtKB:Q14016 xref: UniProtKB:Q6KFX4 xref: UniProtKB:Q8WTV0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022639 ! SCARB1_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017657 ! hrmt1l1-scarb1-1 physical interaction [Term] id: CCO:B0063230 name: Q9Y6X7_HUMAN def: "KIAA0864 protein" [UniProtKB:Q9Y6X7] xref: EMBL:BAA74887.2 xref: UniProtKB:Q9Y6X7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022867 ! KIAA0864_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0006677 ! grb2-egfr-1 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0063231 name: TESK1_HUMAN def: "Dual specificity testis-specific protein kinase 1" [UniProtKB:Q15569] synonym: "EC 2.7.12.1" EXACT [UniProtKB:Q15569] synonym: "Testicular protein kinase 1" EXACT [UniProtKB:Q15569] xref: EMBL:AAH38448.1 xref: EMBL:AAH67130.1 xref: EMBL:BAA09459.1 xref: EMBL:CAI13441.1 xref: EMBL:EAW58375.1 xref: UniProtKB:Q15569 xref: UniProtKB:Q8IXZ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022706 ! TESK1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017665 ! tesk1-spry4 physical interaction relationship: participates_in CCO:I0017666 ! spry4-tesk1 physical interaction relationship: participates_in CCO:I0018474 ! tesk1-spry4-2 physical interaction relationship: participates_in CCO:I0018475 ! tesk1-spry4-3 physical interaction relationship: transforms_into CCO:B0071344 ! TESK1_HUMAN-Phosphoserine220 [Term] id: CCO:B0063232 name: CPSM_HUMAN def: "Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor" [UniProtKB:P31327] synonym: "Carbamoyl-phosphate synthetase I" EXACT [UniProtKB:P31327] synonym: "CPSase I" EXACT [UniProtKB:P31327] synonym: "EC 6.3.4.16" EXACT [UniProtKB:P31327] xref: EMBL:AAD38072.1 xref: EMBL:AAN77181.1 xref: EMBL:AAO31763.1 xref: EMBL:AAP84318.1 xref: EMBL:BAA14328.1 xref: EMBL:CAA75785.1 xref: EMBL:CAE45707.1 xref: UniProtKB:O43774 xref: UniProtKB:P31327 xref: UniProtKB:Q7Z5I5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022152 ! CPS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017679 ! raf1-cps1-1 physical interaction relationship: participates_in CCO:I0017685 ! raf1-cps1-2 physical interaction relationship: participates_in CCO:I0017686 ! raf1-cps1-3 physical interaction relationship: participates_in CCO:I0018050 ! araf-cps1 physical interaction relationship: participates_in CCO:I0018813 ! araf-cps1-1 physical interaction relationship: participates_in CCO:I0018823 ! araf-cps1-2 physical interaction relationship: participates_in CCO:I0019375 ! raf1-cps1 physical interaction relationship: transforms_into CCO:B0065901 ! CPSM_HUMAN-N6-acetyllysine55 relationship: transforms_into CCO:B0065902 ! CPSM_HUMAN-N6-acetyllysine119 relationship: transforms_into CCO:B0065903 ! CPSM_HUMAN-N6-acetyllysine287 relationship: transforms_into CCO:B0065904 ! CPSM_HUMAN-N6-acetyllysine527 relationship: transforms_into CCO:B0065905 ! CPSM_HUMAN-N6-acetyllysine841 relationship: transforms_into CCO:B0065906 ! CPSM_HUMAN-N6-acetyllysine892 relationship: transforms_into CCO:B0065907 ! CPSM_HUMAN-Phosphoserine898 relationship: transforms_into CCO:B0065908 ! CPSM_HUMAN-N6-acetyllysine1291 [Term] id: CCO:B0063233 name: BCA3_HUMAN def: "Proline-rich protein BCA3" [UniProtKB:Q9NQ31] synonym: "AKIP1" EXACT [UniProtKB:Q9NQ31] synonym: "Breast cancer-associated gene 3 protein" EXACT [UniProtKB:Q9NQ31] synonym: "PKA-interacting protein" EXACT [UniProtKB:Q9NQ31] xref: EMBL:AAH30996.1 xref: EMBL:AAM12862.1 xref: EMBL:AAM12863.1 xref: EMBL:AAM12864.1 xref: EMBL:AAM12865.1 xref: EMBL:AAM12866.1 xref: EMBL:AAM12867.1 xref: EMBL:AAM34785.1 xref: EMBL:BAC11537.1 xref: EMBL:CAB92290.1 xref: UniProtKB:Q8NBS2 xref: UniProtKB:Q8TAC6 xref: UniProtKB:Q8TAD3 xref: UniProtKB:Q8TAE0 xref: UniProtKB:Q9NQ31 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022070 ! BCA3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0017699 ! bca3-prkaca-3 physical interaction relationship: participates_in CCO:I0017700 ! bca3-prkaca-4 physical interaction relationship: participates_in CCO:I0017868 ! bca3-prkaca-1 physical interaction relationship: participates_in CCO:I0018013 ! bca3-prkaca-2 physical interaction [Term] id: CCO:B0063234 name: MGN_HUMAN def: "Protein mago nashi homolog" [UniProtKB:P61326] xref: EMBL:AAC39606.1 xref: EMBL:AAD32457.1 xref: EMBL:AAH18211.1 xref: EMBL:CAI18914.1 xref: UniProtKB:O35169 xref: UniProtKB:P50606 xref: UniProtKB:P61326 xref: UniProtKB:Q5SW69 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022400 ! MAGOH_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0017742 ! magoh-ddx48-1 physical interaction relationship: participates_in CCO:I0017948 ! casc3-ddx48 physical interaction relationship: participates_in CCO:I0018062 ! magoh-ddx48-2 physical interaction [Term] id: CCO:B0063235 name: VATC1_HUMAN def: "V-type proton ATPase subunit C 1" [UniProtKB:P21283] synonym: "V-ATPase subunit C 1" EXACT [UniProtKB:P21283] synonym: "Vacuolar proton pump subunit C 1" EXACT [UniProtKB:P21283] xref: EMBL:AAA36803.1 xref: EMBL:AAH10960.1 xref: EMBL:AAL50383.1 xref: EMBL:CAA48903.1 xref: UniProtKB:P21283 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022773 ! ATP6V1C1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017772 ! arf6-atp6v1c1-5 physical interaction relationship: participates_in CCO:I0017947 ! arf6-atp6v1c1-6 physical interaction relationship: participates_in CCO:I0018882 ! arf6-atp6v1c1-2 physical interaction relationship: participates_in CCO:I0019520 ! arf6-atp6v1c1-4 physical interaction relationship: transforms_into CCO:B0071785 ! VATC1_HUMAN-N-acetylthreonine2 [Term] id: CCO:B0063236 name: DDX58_HUMAN def: "Probable ATP-dependent RNA helicase DDX58" [UniProtKB:O95786] synonym: "DEAD-box protein 58" EXACT [UniProtKB:O95786] synonym: "EC 3.6.1.-" EXACT [UniProtKB:O95786] synonym: "Retinoic acid-inducible gene 1 protein" EXACT [UniProtKB:O95786] synonym: "RIG-1" EXACT [UniProtKB:O95786] synonym: "RIG-I" EXACT [UniProtKB:O95786] xref: EMBL:AAD19826.1 xref: EMBL:CAB70840.1 xref: EMBL:CAH71251.1 xref: EMBL:CAH72600.1 xref: EMBL:CAI46068.1 xref: UniProtKB:O95786 xref: UniProtKB:Q5HYE1 xref: UniProtKB:Q5VYT1 xref: UniProtKB:Q9NT04 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022180 ! DDX58_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0017780 ! ddx58-mavs-1 physical interaction [Term] id: CCO:B0063237 name: Q8IUB0_HUMAN def: "Elongation factor 1-alpha" [UniProtKB:Q8IUB0] xref: EMBL:AAN09722.1 xref: EMBL:AAN51932.1 xref: EMBL:BAF82131.1 xref: UniProtKB:Q8IUB0 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017801 ! zbtb16-q8iub0-2 direct interaction relationship: participates_in CCO:I0017829 ! zbtb16-q8iub0-3 physical interaction relationship: participates_in CCO:I0018410 ! zbtb16-q8iub0-1 physical interaction relationship: participates_in CCO:I0018761 ! zbtb16-q8iub0 physical interaction [Term] id: CCO:B0063238 name: ODBB_HUMAN def: "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor" [UniProtKB:P21953] synonym: "BCKDH E1-beta" EXACT [UniProtKB:P21953] synonym: "Branched-chain alpha-keto acid dehydrogenase E1 component beta chain" EXACT [UniProtKB:P21953] synonym: "EC 1.2.4.4" EXACT [UniProtKB:P21953] xref: EMBL:AAA51812.1 xref: EMBL:AAB16763.1 xref: EMBL:AAH40139.1 xref: EMBL:BAA14389.1 xref: EMBL:CAA36685.1 xref: UniProtKB:P21953 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022472 ! BCKDHB_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000382 ! 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003398 ! carboxy-lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000497 ! mitochondrial alpha-ketoglutarate dehydrogenase complex relationship: participates_in CCO:I0017814 ! bckdha-bckdhb-1 direct interaction relationship: participates_in CCO:I0018119 ! bckdha-bckdhb-5 direct interaction relationship: participates_in CCO:I0018120 ! bckdha-bckdhb-6 direct interaction relationship: participates_in CCO:I0018121 ! bckdha-bckdhb-7 direct interaction relationship: participates_in CCO:I0018122 ! bckdha-bckdhb-8 direct interaction relationship: participates_in CCO:I0018252 ! bckdha-bckdhb-2 direct interaction relationship: participates_in CCO:I0018253 ! bckdha-bckdhb-3 direct interaction relationship: participates_in CCO:I0018254 ! bckdha-bckdhb-4 direct interaction relationship: participates_in CCO:I0018711 ! bckdha-bckdhb-9 direct interaction relationship: participates_in CCO:I0018712 ! bckdha-bckdhb-10 direct interaction relationship: participates_in CCO:I0018713 ! bckdha-bckdhb-11 direct interaction relationship: participates_in CCO:I0018714 ! bckdha-bckdhb-12 direct interaction relationship: participates_in CCO:I0018715 ! bckdha-bckdhb-13 direct interaction relationship: participates_in CCO:I0018716 ! bckdha-bckdhb-14 direct interaction [Term] id: CCO:B0063239 name: ICAM3_HUMAN def: "Intercellular adhesion molecule 3 precursor" [UniProtKB:P32942] synonym: "CD50 antigen" EXACT [UniProtKB:P32942] synonym: "CDw50" EXACT [UniProtKB:P32942] synonym: "ICAM-3" EXACT [UniProtKB:P32942] synonym: "ICAM-R" EXACT [UniProtKB:P32942] xref: EMBL:AAB24331.2 xref: EMBL:AAH58903.1 xref: EMBL:ABB01007.1 xref: EMBL:CAA49369.1 xref: EMBL:CAA49473.1 xref: EMBL:EAW84092.1 xref: UniProtKB:P32942 xref: UniProtKB:Q6PD68 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022327 ! ICAM3_human relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0017816 ! icam3-itgal-1 direct interaction [Term] id: CCO:B0063240 name: KPCD1_HUMAN def: "Serine/threonine-protein kinase D1" [UniProtKB:Q15139] synonym: "EC 2.7.11.13" EXACT [UniProtKB:Q15139] synonym: "nPKC-D1" EXACT [UniProtKB:Q15139] synonym: "nPKC-mu" EXACT [UniProtKB:Q15139] synonym: "Protein kinase C mu type" EXACT [UniProtKB:Q15139] synonym: "Protein kinase D" EXACT [UniProtKB:Q15139] xref: EMBL:BAG36853.1 xref: EMBL:CAA53384.1 xref: EMBL:EAW65971.1 xref: UniProtKB:A6NL64 xref: UniProtKB:B2RAF6 xref: UniProtKB:Q15139 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0021046 ! PRKD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017826 ! mt2a-prkd1 physical interaction relationship: participates_in CCO:I0018727 ! mt2a-prkd1-1 physical interaction relationship: participates_in CCO:I0018758 ! prkd1-mt2a-2 physical interaction relationship: participates_in CCO:I0018759 ! mt2a-prkd1-2 colocalization relationship: participates_in CCO:I0019208 ! prkd1-mt2a physical interaction relationship: participates_in CCO:I0019209 ! prkd1-mt2a-1 physical interaction relationship: participates_in CCO:I0019210 ! mt2a-prkd1-3 colocalization relationship: transforms_into CCO:B0067390 ! KPCD1_HUMAN-Phosphotyrosine95 relationship: transforms_into CCO:B0067391 ! KPCD1_HUMAN-Phosphoserine205 relationship: transforms_into CCO:B0067392 ! KPCD1_HUMAN-Phosphothreonine210 relationship: transforms_into CCO:B0067393 ! KPCD1_HUMAN-Phosphotyrosine432 relationship: transforms_into CCO:B0067394 ! KPCD1_HUMAN-Phosphotyrosine463 relationship: transforms_into CCO:B0067395 ! KPCD1_HUMAN-Phosphotyrosine502 relationship: transforms_into CCO:B0067396 ! KPCD1_HUMAN-Phosphoserine738 relationship: transforms_into CCO:B0067397 ! KPCD1_HUMAN-Phosphoserine742 relationship: transforms_into CCO:B0067398 ! KPCD1_HUMAN-Phosphoserine910 [Term] id: CCO:B0063241 name: SNX18_HUMAN def: "Sorting nexin-18" [UniProtKB:Q96RF0] synonym: "SH3 and PX domain-containing protein 3B" EXACT [UniProtKB:Q96RF0] synonym: "Sorting nexin-associated Golgi protein 1" EXACT [UniProtKB:Q96RF0] xref: EMBL:AAH60791.1 xref: EMBL:AAH67860.1 xref: EMBL:AAI17219.1 xref: EMBL:AAI17221.1 xref: EMBL:AAK82415.1 xref: EMBL:EAW54894.1 xref: UniProtKB:Q05BB3 xref: UniProtKB:Q0VG02 xref: UniProtKB:Q96RF0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022665 ! SNX18_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0017836 ! sos1-snag1-1 physical interaction relationship: participates_in CCO:I0017840 ! sos2-snag1-1 physical interaction [Term] id: CCO:B0063242 name: PELI1_HUMAN def: "Protein pellino homolog 1" [UniProtKB:Q96FA3] synonym: "Pellino-1" EXACT [UniProtKB:Q96FA3] synonym: "Pellino-related intracellular-signaling molecule" EXACT [UniProtKB:Q96FA3] xref: EMBL:AAG15393.1 xref: EMBL:AAG17451.1 xref: EMBL:AAH11419.1 xref: EMBL:AAH50019.1 xref: EMBL:AAH63611.1 xref: EMBL:BAB55280.1 xref: EMBL:CAC04320.1 xref: UniProtKB:Q96FA3 xref: UniProtKB:Q96SM0 xref: UniProtKB:Q9GZY5 xref: UniProtKB:Q9HCX0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022501 ! PELI1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017857 ! peli1-irak1-1 physical interaction relationship: participates_in CCO:I0018034 ! pellino-irak-irak4 physical interaction [Term] id: CCO:B0063243 name: TAB3_HUMAN def: "Mitogen-activated protein kinase kinase kinase 7-interacting protein 3" [UniProtKB:Q8N5C8] synonym: "NF-kappa-B-activating protein 1" EXACT [UniProtKB:Q8N5C8] synonym: "TAK1-binding protein 3" EXACT [UniProtKB:Q8N5C8] xref: EMBL:AAH32526.1 xref: EMBL:AAQ88279.1 xref: EMBL:AAQ92938.1 xref: EMBL:AAQ92939.1 xref: EMBL:AAR06179.1 xref: UniProtKB:Q6VQR0 xref: UniProtKB:Q8N5C8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022699 ! MAP3K7IP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017858 ! peli1-irak1-2 physical interaction relationship: transforms_into CCO:B0071076 ! TAB3_HUMAN-Phosphoserine60 relationship: transforms_into CCO:B0071077 ! TAB3_HUMAN-Phosphothreonine404 relationship: transforms_into CCO:B0071078 ! TAB3_HUMAN-Phosphoserine408 relationship: transforms_into CCO:B0071079 ! TAB3_HUMAN-Phosphoserine492 [Term] id: CCO:B0063244 name: HTRA2_HUMAN def: "Serine protease HTRA2, mitochondrial precursor" [UniProtKB:O43464] synonym: "EC 3.4.21.108" EXACT [UniProtKB:O43464] synonym: "High temperature requirement protein A2" EXACT [UniProtKB:O43464] synonym: "HtrA2" EXACT [UniProtKB:O43464] synonym: "Omi stress-regulated endoprotease" EXACT [UniProtKB:O43464] synonym: "Serine protease 25" EXACT [UniProtKB:O43464] synonym: "Serine proteinase OMI" EXACT [UniProtKB:O43464] xref: EMBL:AAB94569.2 xref: EMBL:AAF66596.1 xref: EMBL:AAF66597.1 xref: EMBL:AAF66598.1 xref: EMBL:AAG13126.1 xref: EMBL:AAH00096.1 xref: UniProtKB:O43464 xref: UniProtKB:Q9HBZ4 xref: UniProtKB:Q9P0Y3 xref: UniProtKB:Q9P0Y4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022323 ! HTRA2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000341 ! mitochondrial intermembrane space relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: participates_in CCO:I0017873 ! birc7-prss25-2 physical interaction relationship: participates_in CCO:I0017875 ! birc4-prss25-3 physical interaction relationship: participates_in CCO:I0018029 ! birc7-prss25-1 physical interaction relationship: participates_in CCO:I0018030 ! birc4-prss25-2 physical interaction relationship: participates_in CCO:I0019357 ! omi-xiap physical interaction relationship: participates_in CCO:I0019358 ! omi-xiap-1 physical interaction [Term] id: CCO:B0063245 name: GCKR_HUMAN def: "Glucokinase regulatory protein" [UniProtKB:Q14397] synonym: "Glucokinase regulator" EXACT [UniProtKB:Q14397] xref: EMBL:AAP72013.1 xref: EMBL:AAY14850.1 xref: EMBL:CAA70779.2 xref: EMBL:CAA88367.1 xref: EMBL:CAB61828.1 xref: UniProtKB:Q14397 xref: UniProtKB:Q53RY6 xref: UniProtKB:Q99522 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022269 ! GCKR_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0017891 ! gck-gckr-3 direct interaction relationship: participates_in CCO:I0018074 ! gck-gckr-2 direct interaction [Term] id: CCO:B0063246 name: CASC3_HUMAN def: "Protein CASC3" [UniProtKB:O15234] synonym: "Btz" EXACT [UniProtKB:O15234] synonym: "Cancer susceptibility candidate gene 3 protein" EXACT [UniProtKB:O15234] synonym: "Metastatic lymph node protein 51" EXACT [UniProtKB:O15234] synonym: "Protein barentsz" EXACT [UniProtKB:O15234] synonym: "Protein MLN 51" EXACT [UniProtKB:O15234] xref: EMBL:AAH44656.1 xref: EMBL:AAH50526.1 xref: EMBL:CAC27699.1 xref: UniProtKB:O15234 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022088 ! CASC3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017948 ! casc3-ddx48 physical interaction relationship: participates_in CCO:I0017949 ! casc3-ddx48-1 physical interaction relationship: participates_in CCO:I0018578 ! btz-eif4aiii physical interaction relationship: transforms_into CCO:B0065820 ! CASC3_HUMAN-Phosphoserine363 relationship: transforms_into CCO:B0065821 ! CASC3_HUMAN-Phosphoserine373 [Term] id: CCO:B0063247 name: SAE2_HUMAN def: "SUMO-activating enzyme subunit 2" [UniProtKB:Q9UBT2] synonym: "Anthracycline-associated resistance ARX" EXACT [UniProtKB:Q9UBT2] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q9UBT2] synonym: "Ubiquitin-like 1-activating enzyme E1B" EXACT [UniProtKB:Q9UBT2] xref: EMBL:AAC99992.1 xref: EMBL:AAD12784.1 xref: EMBL:AAD23914.1 xref: EMBL:AAD24434.1 xref: EMBL:AAH03153.1 xref: EMBL:AAP88783.1 xref: EMBL:BAA34795.1 xref: EMBL:BAD92109.1 xref: EMBL:CAB66839.1 xref: EMBL:CAG33037.1 xref: UniProtKB:O95605 xref: UniProtKB:Q59H87 xref: UniProtKB:Q6IBP6 xref: UniProtKB:Q9NTJ1 xref: UniProtKB:Q9UBT2 xref: UniProtKB:Q9UED2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022633 ! UBA2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0017956 ! sumo1-uble1a-2 physical interaction relationship: participates_in CCO:I0018263 ! dj_1-uba2 physical interaction relationship: transforms_into CCO:B0070290 ! SAE2_HUMAN-Phosphoserine592 [Term] id: CCO:B0063248 name: HA25_HUMAN def: "HLA class II histocompatibility antigen, DQ(5) alpha chain precursor" [UniProtKB:P01907] synonym: "DC-1 alpha chain" EXACT [UniProtKB:P01907] xref: EMBL:AAA59707.1 xref: EMBL:AAA59758.1 xref: EMBL:AAA74633.1 xref: EMBL:AAU87978.1 xref: EMBL:AAU88007.1 xref: EMBL:AAU88022.1 xref: EMBL:AAU88028.1 xref: EMBL:ABA86855.1 xref: EMBL:CAA25141.1 xref: EMBL:CAI18230.1 xref: EMBL:CAJ14960.1 xref: UniProtKB:P01907 xref: UniProtKB:Q06751 xref: UniProtKB:Q29994 xref: UniProtKB:Q30086 xref: UniProtKB:Q5Y7D5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004776 ! HLA-DQA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001670 ! MHC class II protein complex relationship: participates_in CCO:I0017957 ! hcrt-hla_dqa1-1 physical interaction [Term] id: CCO:B0063249 name: HB25_HUMAN def: "HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor" [UniProtKB:P03992] synonym: "DC-1" EXACT [UniProtKB:P03992] synonym: "DQ(5)" EXACT [UniProtKB:P03992] xref: EMBL:AAA36247.1 xref: EMBL:AAA59677.1 xref: EMBL:AAA59697.1 xref: EMBL:AAA59762.1 xref: EMBL:AAA59769.1 xref: EMBL:AAC41973.1 xref: UniProtKB:O19713 xref: UniProtKB:O78223 xref: UniProtKB:P03992 xref: UniProtKB:Q29966 xref: UniProtKB:Q30082 xref: UniProtKB:Q30089 xref: UniProtKB:Q30095 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0011773 ! HLA-DQB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001670 ! MHC class II protein complex relationship: participates_in CCO:I0017957 ! hcrt-hla_dqa1-1 physical interaction [Term] id: CCO:B0063250 name: OS9_HUMAN def: "Protein OS-9 precursor" [UniProtKB:Q13438] synonym: "Amplified in osteosarcoma 9" EXACT [UniProtKB:Q13438] xref: EMBL:AAB06495.1 xref: EMBL:AAC39523.2 xref: EMBL:BAA24362.1 xref: EMBL:BAA24363.1 xref: EMBL:EAW97046.1 xref: UniProtKB:A6NDD1 xref: UniProtKB:O00579 xref: UniProtKB:Q13438 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022484 ! OS9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: participates_in CCO:I0007175 ! hif1a-os9-4 direct interaction relationship: participates_in CCO:I0017966 ! os9-egln1 physical interaction relationship: participates_in CCO:I0017967 ! os9-egln1-1 physical interaction relationship: participates_in CCO:I0017968 ! os9-hif1a physical interaction relationship: participates_in CCO:I0017969 ! os9-egln1-2 physical interaction relationship: participates_in CCO:I0017970 ! os9-egln1-3 physical interaction relationship: participates_in CCO:I0018125 ! hif1a-os9 physical interaction relationship: participates_in CCO:I0018265 ! hif1a-os9-1 direct interaction relationship: participates_in CCO:I0018266 ! os9-egln3-1 physical interaction relationship: participates_in CCO:I0018267 ! hif1a-os9-5 direct interaction [Term] id: CCO:B0063251 name: TIM44_HUMAN def: "Mitochondrial import inner membrane translocase subunit TIM44 precursor" [UniProtKB:O43615] xref: EMBL:AAB97740.1 xref: EMBL:AAH33628.1 xref: UniProtKB:O43615 xref: UniProtKB:Q8N193 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022715 ! TIMM44_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000330 ! mitochondrial inner membrane presequence translocase complex relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0018049 ! araf-htim44 physical interaction relationship: participates_in CCO:I0018805 ! araf-htim44-1 physical interaction relationship: participates_in CCO:I0018817 ! araf-htim44-2 physical interaction [Term] id: CCO:B0063252 name: ASSY_HUMAN def: "Argininosuccinate synthase" [UniProtKB:P00966] synonym: "Citrulline--aspartate ligase" EXACT [UniProtKB:P00966] synonym: "EC 6.3.4.5" EXACT [UniProtKB:P00966] xref: EMBL:AAA51782.1 xref: EMBL:AAA51783.1 xref: EMBL:AAH09243.1 xref: EMBL:AAH21676.1 xref: EMBL:AAH52288.1 xref: EMBL:AAK67487.1 xref: EMBL:CAA25771.1 xref: UniProtKB:P00966 xref: UniProtKB:Q6LDL2 xref: UniProtKB:Q86UZ0 xref: UniProtKB:Q96GT4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022053 ! ASS1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000530 ! argininosuccinate synthase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018052 ! araf-ass physical interaction relationship: participates_in CCO:I0018806 ! araf-ass-1 physical interaction relationship: participates_in CCO:I0018818 ! araf-ass-2 physical interaction relationship: participates_in CCO:I0018824 ! araf-ass-3 physical interaction relationship: participates_in CCO:I0019660 ! ascc2-ass physical interaction relationship: transforms_into CCO:B0065754 ! ASSY_HUMAN-Phosphoserine352 [Term] id: CCO:B0063253 name: NUD14_HUMAN def: "Uridine diphosphate glucose pyrophosphatase" [UniProtKB:O95848] synonym: "EC 3.6.1.45" EXACT [UniProtKB:O95848] synonym: "Nucleoside diphosphate-linked moiety X motif 14" EXACT [UniProtKB:O95848] synonym: "Nudix motif 14" EXACT [UniProtKB:O95848] synonym: "UDPG pyrophosphatase" EXACT [UniProtKB:O95848] synonym: "UGPPase" EXACT [UniProtKB:O95848] xref: EMBL:AAD15563.1 xref: EMBL:AAH41584.1 xref: EMBL:BAC65455.1 xref: UniProtKB:O95848 xref: UniProtKB:Q86SJ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022463 ! NUDT14_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002114 ! UDP-sugar diphosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018054 ! araf-nudt14 physical interaction relationship: participates_in CCO:I0018810 ! araf-nudt14-1 physical interaction relationship: participates_in CCO:I0018819 ! araf-nudt14-2 physical interaction relationship: participates_in CCO:I0019372 ! raf1-nudt14 physical interaction [Term] id: CCO:B0063254 name: IL33_HUMAN def: "Interleukin-33 precursor" [UniProtKB:O95760] synonym: "IL-1F11" EXACT [UniProtKB:O95760] synonym: "IL-33" EXACT [UniProtKB:O95760] synonym: "Interleukin-1 family member 11" EXACT [UniProtKB:O95760] synonym: "NF-HEV" EXACT [UniProtKB:O95760] synonym: "Nuclear factor from high endothelial venules" EXACT [UniProtKB:O95760] xref: EMBL:AAH47085.1 xref: EMBL:AAX86998.1 xref: EMBL:BAA75892.1 xref: EMBL:CAG28547.1 xref: EMBL:CAI16003.1 xref: UniProtKB:O95760 xref: UniProtKB:Q2YEJ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022337 ! IL33_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0018100 ! c9orf26-il1rl1-1 direct interaction relationship: participates_in CCO:I0019313 ! il1rl1-c9orf26-1 direct interaction [Term] id: CCO:B0063255 name: CN37_HUMAN def: "2',3'-cyclic-nucleotide 3'-phosphodiesterase" [UniProtKB:P09543] synonym: "CNP" EXACT [UniProtKB:P09543] synonym: "CNPase" EXACT [UniProtKB:P09543] synonym: "EC 3.1.4.37" EXACT [UniProtKB:P09543] xref: EMBL:AAA35704.1 xref: EMBL:AAB23928.2 xref: EMBL:AAB24298.2 xref: EMBL:AAH01362.1 xref: EMBL:AAH06392.1 xref: EMBL:AAH11046.1 xref: EMBL:AAH28040.1 xref: EMBL:BAA02435.1 xref: EMBL:BAA39694.1 xref: UniProtKB:P09543 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022140 ! CNP_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000585 ! 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: transforms_into CCO:B0065886 ! CN37_HUMAN-Phosphotyrosine110 relationship: transforms_into CCO:B0065887 ! CN37_HUMAN-Phosphotyrosine373 [Term] id: CCO:B0063256 name: TMM33_HUMAN def: "Transmembrane protein 33" [UniProtKB:P57088] synonym: "Protein DB83" EXACT [UniProtKB:P57088] xref: EMBL:AAH00948.2 xref: EMBL:BAA91665.1 xref: EMBL:BAB14384.1 xref: EMBL:CAG33541.1 xref: UniProtKB:P57088 xref: UniProtKB:Q9H953 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022722 ! TMEM33_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction [Term] id: CCO:B0063257 name: PDIA6_HUMAN def: "Protein disulfide-isomerase A6 precursor" [UniProtKB:Q15084] synonym: "EC 5.3.4.1" EXACT [UniProtKB:Q15084] synonym: "Protein disulfide isomerase P5" EXACT [UniProtKB:Q15084] synonym: "Thioredoxin domain-containing protein 7" EXACT [UniProtKB:Q15084] xref: EMBL:AAB50217.1 xref: EMBL:AAH01312.1 xref: EMBL:BAA08450.1 xref: EMBL:BAC86977.1 xref: UniProtKB:Q15084 xref: UniProtKB:Q6ZSH5 xref: UniProtKB:Q99778 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022496 ! PDIA6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007051 ! mit1a-ef1-fila physical interaction relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: transforms_into CCO:B0069187 ! PDIA6_HUMAN-Phosphoserine428 [Term] id: CCO:B0063258 name: VPS35_HUMAN def: "Vacuolar protein sorting-associated protein 35" [UniProtKB:Q96QK1] synonym: "hVPS35" EXACT [UniProtKB:Q96QK1] synonym: "Maternal-embryonic 3" EXACT [UniProtKB:Q96QK1] synonym: "Vesicle protein sorting 35" EXACT [UniProtKB:Q96QK1] xref: EMBL:AAF02778.2 xref: EMBL:AAF89953.1 xref: EMBL:AAG01989.1 xref: EMBL:AAG09687.1 xref: EMBL:AAG40619.1 xref: EMBL:AAH02414.1 xref: EMBL:AAH10362.1 xref: EMBL:AAH93036.1 xref: EMBL:BAA91137.1 xref: EMBL:BAA91790.1 xref: EMBL:BAB14626.1 xref: EMBL:CAB66822.1 xref: EMBL:CAC21686.1 xref: UniProtKB:Q561W2 xref: UniProtKB:Q96QK1 xref: UniProtKB:Q9H016 xref: UniProtKB:Q9H096 xref: UniProtKB:Q9H4P3 xref: UniProtKB:Q9H8J0 xref: UniProtKB:Q9NRS7 xref: UniProtKB:Q9NVG2 xref: UniProtKB:Q9NX80 xref: UniProtKB:Q9NZK2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022778 ! VPS35_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0007052 ! mit1b-ef1-fila-1 physical interaction relationship: transforms_into CCO:B0071817 ! VPS35_HUMAN-Phosphoserine7 relationship: transforms_into CCO:B0071818 ! VPS35_HUMAN-Phosphotyrosine791 [Term] id: CCO:B0063259 name: APBB3_HUMAN def: "Amyloid beta A4 precursor protein-binding family B member 3" [UniProtKB:O95704] synonym: "Fe65-like protein 2" EXACT [UniProtKB:O95704] synonym: "Fe65L2" EXACT [UniProtKB:O95704] xref: EMBL:AAF65172.1 xref: EMBL:AAF65173.1 xref: EMBL:AAF65174.1 xref: EMBL:AAF65175.1 xref: EMBL:AAI25188.1 xref: EMBL:BAA35188.1 xref: EMBL:BAA78674.1 xref: UniProtKB:O95704 xref: UniProtKB:Q08AG4 xref: UniProtKB:Q9NYX6 xref: UniProtKB:Q9NYX7 xref: UniProtKB:Q9NYX8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022041 ! APBB3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018133 ! app-apbb3 physical interaction relationship: participates_in CCO:I0018134 ! apbb3-aplp2 physical interaction [Term] id: CCO:B0063260 name: RL1D1_HUMAN def: "Ribosomal L1 domain-containing protein 1" [UniProtKB:O76021] synonym: "CATX-11" EXACT [UniProtKB:O76021] synonym: "Cellular senescence-inhibited gene protein" EXACT [UniProtKB:O76021] synonym: "Protein PBK1" EXACT [UniProtKB:O76021] xref: EMBL:AAF98239.1 xref: EMBL:AAH19069.2 xref: EMBL:AAI12229.1 xref: EMBL:AAI13700.1 xref: EMBL:AAN46298.1 xref: EMBL:AAT06742.1 xref: EMBL:CAA07491.1 xref: EMBL:CAB43231.2 xref: UniProtKB:O76021 xref: UniProtKB:Q2M1T7 xref: UniProtKB:Q6PL22 xref: UniProtKB:Q8IWS7 xref: UniProtKB:Q8WUZ1 xref: UniProtKB:Q9HDA9 xref: UniProtKB:Q9Y3Z9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022571 ! RSL1D1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007072 ! c20orf20-epc1-2 physical interaction relationship: transforms_into CCO:B0070067 ! RL1D1_HUMAN-Phosphothreonine340 relationship: transforms_into CCO:B0070068 ! RL1D1_HUMAN-Phosphothreonine358 relationship: transforms_into CCO:B0070069 ! RL1D1_HUMAN-Phosphoserine361 relationship: transforms_into CCO:B0070070 ! RL1D1_HUMAN-Phosphoserine392 relationship: transforms_into CCO:B0070071 ! RL1D1_HUMAN-Phosphoserine396 relationship: transforms_into CCO:B0070072 ! RL1D1_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0070073 ! RL1D1_HUMAN-Phosphothreonine423 relationship: transforms_into CCO:B0070074 ! RL1D1_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0070075 ! RL1D1_HUMAN-Phosphoserine443 relationship: transforms_into CCO:B0070076 ! RL1D1_HUMAN-Phosphothreonine465 relationship: transforms_into CCO:B0070077 ! RL1D1_HUMAN-Phosphoserine467 [Term] id: CCO:B0063261 name: PELI2_HUMAN def: "Protein pellino homolog 2" [UniProtKB:Q9HAT8] synonym: "Pellino-2" EXACT [UniProtKB:Q9HAT8] xref: EMBL:AAG15390.1 xref: EMBL:AAH09476.1 xref: UniProtKB:Q9HAT8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022502 ! PELI2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018146 ! irak4-peli2-4 phosphorylation relationship: participates_in CCO:I0018147 ! irak1-peli2-3 physical interaction relationship: participates_in CCO:I0018773 ! irak1-peli2-2 physical interaction relationship: participates_in CCO:I0018774 ! irak4-peli2-3 physical interaction relationship: participates_in CCO:I0019233 ! irak4-peli2-1 physical interaction [Term] id: CCO:B0063262 name: CNRP1_HUMAN def: "CB1 cannabinoid receptor-interacting protein 1" [UniProtKB:Q96F85] synonym: "CRIP-1" EXACT [UniProtKB:Q96F85] xref: EMBL:AAH11535.1 xref: EMBL:AAH35125.1 xref: EMBL:AAN41658.1 xref: EMBL:AAX93120.1 xref: EMBL:BAG34727.1 xref: EMBL:CAB53688.1 xref: EMBL:EAW99877.1 xref: UniProtKB:B2R4D0 xref: UniProtKB:Q49AN4 xref: UniProtKB:Q96F85 xref: UniProtKB:Q9UFZ0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022141 ! CNRIP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018232 ! gch1-cb1_1p1-1 physical interaction relationship: participates_in CCO:I0018625 ! gch1-cb1_1p1 physical interaction [Term] id: CCO:B0063263 name: GFRP_HUMAN def: "GTP cyclohydrolase 1 feedback regulatory protein" [UniProtKB:P30047] synonym: "GFRP" EXACT [UniProtKB:P30047] synonym: "GTP cyclohydrolase I feedback regulatory protein" EXACT [UniProtKB:P30047] synonym: "p35" EXACT [UniProtKB:P30047] xref: EMBL:AAB37337.1 xref: EMBL:AAI12263.1 xref: EMBL:AAI12265.1 xref: UniProtKB:P30047 xref: UniProtKB:Q2M1Q2 xref: UniProtKB:Q99749 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022276 ! GCHFR_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018237 ! gch1-grfp physical interaction [Term] id: CCO:B0063264 name: CX04A_HUMAN def: "Protein CXorf40A" [UniProtKB:Q8TE69] synonym: "Endothelial-overexpressed lipopolysaccharide-associated factor 1" EXACT [UniProtKB:Q8TE69] xref: EMBL:AAH65539.1 xref: EMBL:AAI04931.1 xref: EMBL:AAI04933.1 xref: EMBL:AAL71889.1 xref: UniProtKB:Q2M3E9 xref: UniProtKB:Q8TE69 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022165 ! CXorf40A_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018248 ! mt2a-cxorf40a-2 physical interaction relationship: participates_in CCO:I0018564 ! cxorf40a-mt2a-1 physical interaction [Term] id: CCO:B0063265 name: SNTA1_HUMAN def: "Alpha-1-syntrophin" [UniProtKB:Q13424] synonym: "59 kDa dystrophin-associated protein A1 acidic component 1" EXACT [UniProtKB:Q13424] synonym: "Pro-TGF-alpha cytoplasmic domain-interacting protein 1" EXACT [UniProtKB:Q13424] synonym: "Syntrophin-1" EXACT [UniProtKB:Q13424] synonym: "TACIP1" EXACT [UniProtKB:Q13424] xref: EMBL:AAB36398.1 xref: EMBL:AAC50448.1 xref: EMBL:AAH26215.1 xref: EMBL:CAC15884.1 xref: UniProtKB:Q13424 xref: UniProtKB:Q16438 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022662 ! SNTA1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018347 ! abca1-utrn physical interaction relationship: participates_in CCO:I0018349 ! abca1-snta1 physical interaction relationship: participates_in CCO:I0020173 ! snta1-g22p1 physical interaction relationship: participates_in CCO:I0020668 ! snta1-med8 physical interaction relationship: transforms_into CCO:B0070697 ! SNTA1_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0070698 ! SNTA1_HUMAN-Phosphoserine193 [Term] id: CCO:B0063266 name: SNTB1_HUMAN def: "Beta-1-syntrophin" [UniProtKB:Q13884] synonym: "59 kDa dystrophin-associated protein A1 basic component 1" EXACT [UniProtKB:Q13884] synonym: "BSYN2" EXACT [UniProtKB:Q13884] synonym: "DAPA1B" EXACT [UniProtKB:Q13884] synonym: "Syntrophin-2" EXACT [UniProtKB:Q13884] synonym: "Tax interaction protein 43" EXACT [UniProtKB:Q13884] synonym: "TIP-43" EXACT [UniProtKB:Q13884] xref: EMBL:AAA81523.1 xref: EMBL:AAB84253.1 xref: EMBL:AAH98573.1 xref: UniProtKB:O14912 xref: UniProtKB:Q13884 xref: UniProtKB:Q4KMG8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022663 ! SNTB1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018347 ! abca1-utrn physical interaction relationship: participates_in CCO:I0018348 ! abca1-sntb1-1 physical interaction relationship: participates_in CCO:I0018676 ! abca1-sntb1 physical interaction relationship: transforms_into CCO:B0070699 ! SNTB1_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0070700 ! SNTB1_HUMAN-Phosphoserine87 relationship: transforms_into CCO:B0070701 ! SNTB1_HUMAN-Phosphothreonine214 relationship: transforms_into CCO:B0070702 ! SNTB1_HUMAN-Phosphoserine219 relationship: transforms_into CCO:B0070703 ! SNTB1_HUMAN-Phosphoserine236 relationship: transforms_into CCO:B0070704 ! SNTB1_HUMAN-Phosphoserine389 [Term] id: CCO:B0063267 name: ACCN1_HUMAN def: "Amiloride-sensitive cation channel 1, neuronal" [UniProtKB:Q16515] synonym: "Acid-sensing ion channel 2" EXACT [UniProtKB:Q16515] synonym: "Amiloride-sensitive brain sodium channel" EXACT [UniProtKB:Q16515] synonym: "Amiloride-sensitive cation channel neuronal 1" EXACT [UniProtKB:Q16515] synonym: "ASIC2" EXACT [UniProtKB:Q16515] synonym: "BNaC1" EXACT [UniProtKB:Q16515] synonym: "BNC1" EXACT [UniProtKB:Q16515] synonym: "Brain sodium channel 1" EXACT [UniProtKB:Q16515] synonym: "Mammalian degenerin homolog" EXACT [UniProtKB:Q16515] xref: EMBL:AAB49182.1 xref: EMBL:AAC50432.1 xref: EMBL:AAC50498.1 xref: EMBL:AAH75042.1 xref: EMBL:AAH75043.1 xref: EMBL:CAD38879.1 xref: UniProtKB:Q13553 xref: UniProtKB:Q16515 xref: UniProtKB:Q6DJU1 xref: UniProtKB:Q8N3E2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022023 ! ACCN1_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001527 ! sodium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002737 ! amiloride-sensitive sodium channel activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018352 ! acnn1-prkcabp-1 physical interaction relationship: participates_in CCO:I0018353 ! accn1-prkcabp-1 physical interaction relationship: participates_in CCO:I0018567 ! accn1-prkcabp-2 physical interaction [Term] id: CCO:B0063268 name: MPDZ_HUMAN def: "Multiple PDZ domain protein" [UniProtKB:O75970] synonym: "Multi-PDZ domain protein 1" EXACT [UniProtKB:O75970] xref: EMBL:AAC61870.1 xref: EMBL:BAC05409.1 xref: EMBL:CAA04680.1 xref: EMBL:CAH71899.1 xref: EMBL:CAH71900.1 xref: EMBL:CAI40490.1 xref: EMBL:CAI40491.1 xref: EMBL:CAI40492.1 xref: EMBL:CAI40493.1 xref: EMBL:CAI40494.1 xref: EMBL:CAI40495.1 xref: EMBL:CAI41236.1 xref: EMBL:CAI41237.1 xref: EMBL:CAI41238.1 xref: EMBL:CAI41239.1 xref: EMBL:CAI41240.1 xref: EMBL:CAI56786.1 xref: EMBL:EAW58704.1 xref: UniProtKB:A6NLC2 xref: UniProtKB:O43798 xref: UniProtKB:O75970 xref: UniProtKB:Q5CZ80 xref: UniProtKB:Q5JTX3 xref: UniProtKB:Q5JTX6 xref: UniProtKB:Q5JTX7 xref: UniProtKB:Q5JUC3 xref: UniProtKB:Q5JUC4 xref: UniProtKB:Q5VZ62 xref: UniProtKB:Q8N790 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022406 ! MPDZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018360 ! abca1-mpdz physical interaction relationship: transforms_into CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: transforms_into CCO:B0068253 ! MPDZ_HUMAN-Phosphoserine483 [Term] id: CCO:B0063269 name: LIN7B_HUMAN def: "Lin-7 homolog B" [UniProtKB:Q9HAP6] synonym: "hLin7B" EXACT [UniProtKB:Q9HAP6] synonym: "hVeli2" EXACT [UniProtKB:Q9HAP6] synonym: "Lin-7B" EXACT [UniProtKB:Q9HAP6] synonym: "MALS-2" EXACT [UniProtKB:Q9HAP6] synonym: "Mammalian lin-seven protein 2" EXACT [UniProtKB:Q9HAP6] synonym: "Veli-2 protein" EXACT [UniProtKB:Q9HAP6] synonym: "Vertebrate lin-7 homolog 2" EXACT [UniProtKB:Q9HAP6] xref: EMBL:AAG34117.1 xref: EMBL:AAH27618.1 xref: EMBL:AAQ89104.1 xref: UniProtKB:Q9HAP6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022370 ! LIN7B_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0018362 ! abca1-lin7b physical interaction [Term] id: CCO:B0063270 name: DZIP1_HUMAN def: "Zinc finger protein DZIP1" [UniProtKB:Q86YF9] synonym: "DAZ-interacting protein 1/2" EXACT [UniProtKB:Q86YF9] xref: EMBL:AAH41804.1 xref: EMBL:AAL36978.1 xref: EMBL:AAL36979.1 xref: EMBL:BAA76840.2 xref: EMBL:CAB43211.2 xref: EMBL:CAH71601.1 xref: UniProtKB:Q5W078 xref: UniProtKB:Q86YF9 xref: UniProtKB:Q8WY45 xref: UniProtKB:Q8WY46 xref: UniProtKB:Q9UGA5 xref: UniProtKB:Q9Y2K0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022202 ! DZIP1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0018393 ! daz1-dzip1-1 physical interaction [Term] id: CCO:B0063271 name: DZIP3_HUMAN def: "E3 ubiquitin-protein ligase DZIP3" [UniProtKB:Q86Y13] synonym: "DAZ-interacting protein 3" EXACT [UniProtKB:Q86Y13] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q86Y13] synonym: "hRUL138" EXACT [UniProtKB:Q86Y13] synonym: "RNA-binding ubiquitin ligase of 138 kDa" EXACT [UniProtKB:Q86Y13] xref: EMBL:AAH39018.1 xref: EMBL:AAH56674.1 xref: EMBL:AAH63882.1 xref: EMBL:AAK69484.1 xref: EMBL:AAO72967.1 xref: EMBL:AAO72968.1 xref: EMBL:AAO72969.1 xref: EMBL:AAO72970.1 xref: EMBL:BAA31650.2 xref: UniProtKB:O75162 xref: UniProtKB:Q6P3R9 xref: UniProtKB:Q6PH82 xref: UniProtKB:Q86Y13 xref: UniProtKB:Q86Y14 xref: UniProtKB:Q86Y15 xref: UniProtKB:Q86Y16 xref: UniProtKB:Q8IWI0 xref: UniProtKB:Q96RS9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022203 ! DZIP3_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004687 ! polyubiquitin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018394 ! daz1-dzip3-1 physical interaction relationship: participates_in CCO:I0019029 ! atxn1-dzip3 physical interaction [Term] id: CCO:B0063272 name: Q8WY44_HUMAN def: "Quaking protein 3" [UniProtKB:Q8WY44] xref: EMBL:AAL36980.1 xref: UniProtKB:Q8WY44 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022849 ! QK3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018396 ! daz1-qk3-1 physical interaction [Term] id: CCO:B0063273 name: GHR_HUMAN def: "Growth hormone receptor precursor" [UniProtKB:P10912] synonym: "GH receptor" EXACT [UniProtKB:P10912] synonym: "Somatotropin receptor" EXACT [UniProtKB:P10912] xref: EMBL:AAA52555.1 xref: EMBL:CAA29808.1 xref: EMBL:CAC06613.1 xref: UniProtKB:P10912 xref: UniProtKB:Q9HCX2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022277 ! GHR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001250 ! growth hormone receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018413 ! ghr-ncoa6-1 physical interaction relationship: participates_in CCO:I0018423 ! ncoa6-ghr-2 physical interaction relationship: participates_in CCO:I0019182 ! gh1-ghr-3 direct interaction relationship: participates_in CCO:I0019320 ! gh1-ghr-1 direct interaction relationship: participates_in CCO:I0019321 ! gh1-ghr-2 direct interaction [Term] id: CCO:B0063274 name: SMYD3_HUMAN def: "SET and MYND domain-containing protein 3" [UniProtKB:Q9H7B4] synonym: "EC 2.1.1.43" EXACT [UniProtKB:Q9H7B4] synonym: "Zinc finger MYND domain-containing protein 1" EXACT [UniProtKB:Q9H7B4] xref: EMBL:AAH17079.2 xref: EMBL:AAH31010.1 xref: EMBL:AAO31695.1 xref: EMBL:BAB14981.1 xref: EMBL:BAB86333.1 xref: EMBL:CAI14744.1 xref: EMBL:CAI14745.1 xref: EMBL:CAI14746.1 xref: EMBL:CAI15419.1 xref: EMBL:CAI16395.1 xref: EMBL:CAI16628.1 xref: EMBL:CAI16629.1 xref: EMBL:CAI16630.1 xref: EMBL:EAW77142.1 xref: UniProtKB:B1AN38 xref: UniProtKB:Q86TL8 xref: UniProtKB:Q8N5Z6 xref: UniProtKB:Q96AI5 xref: UniProtKB:Q9H7B4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022658 ! SMYD3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018439 ! pbx2-smyd3 physical interaction [Term] id: CCO:B0063275 name: ZDHC7_HUMAN def: "Palmitoyltransferase ZDHHC7" [UniProtKB:Q9NXF8] synonym: "DHHC-7" EXACT [UniProtKB:Q9NXF8] synonym: "EC 2.3.1.-" EXACT [UniProtKB:Q9NXF8] synonym: "Zinc finger DHHC domain-containing protein 7" EXACT [UniProtKB:Q9NXF8] synonym: "Zinc finger protein 370" EXACT [UniProtKB:Q9NXF8] xref: EMBL:AAH17702.1 xref: EMBL:AAH18772.1 xref: EMBL:BAA91055.1 xref: EMBL:BAA91814.1 xref: UniProtKB:Q8WV42 xref: UniProtKB:Q9NVD8 xref: UniProtKB:Q9NXF8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022800 ! ZDHHC7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003132 ! palmitoyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018440 ! pbx2-zdhhc7 physical interaction [Term] id: CCO:B0063276 name: CS029_HUMAN def: "Uncharacterized protein C19orf29" [UniProtKB:Q8WUQ7] synonym: "Renal carcinoma antigen NY-REN-24" EXACT [UniProtKB:Q8WUQ7] xref: EMBL:AAC24305.1 xref: EMBL:AAC32903.1 xref: EMBL:AAD42868.1 xref: EMBL:AAH04262.1 xref: EMBL:AAH19848.1 xref: EMBL:EAW69298.1 xref: UniProtKB:A6NNA9 xref: UniProtKB:O75229 xref: UniProtKB:Q7LE08 xref: UniProtKB:Q8WUQ7 xref: UniProtKB:Q9BTA6 xref: UniProtKB:Q9Y5A4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022154 ! C19orf29_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: participates_in CCO:I0018469 ! lst1-q8wuq7 physical interaction relationship: transforms_into CCO:B0065909 ! CS029_HUMAN-Phosphoserine421 [Term] id: CCO:B0063277 name: Q8NG21_HUMAN def: "Putative regulatory uORF" [UniProtKB:Q8NG21] xref: EMBL:AAM69366.1 xref: UniProtKB:Q8NG21 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022847 ! EIF4GI_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018484 ! ddx48-eif4gi physical interaction [Term] id: CCO:B0063278 name: TOM1_HUMAN def: "Target of Myb protein 1" [UniProtKB:O60784] xref: EMBL:CAA07362.1 xref: EMBL:CAG30481.1 xref: EMBL:CAI17951.1 xref: EMBL:CAI21633.1 xref: UniProtKB:O60784 xref: UniProtKB:Q5TIJ6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022726 ! TOM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018524 ! tom1-tollip-3 physical interaction relationship: transforms_into CCO:B0071443 ! TOM1_HUMAN-Phosphoserine130 relationship: transforms_into CCO:B0071444 ! TOM1_HUMAN-Phosphoserine131 relationship: transforms_into CCO:B0071445 ! TOM1_HUMAN-Phosphothreonine139 relationship: transforms_into CCO:B0071446 ! TOM1_HUMAN-Phosphothreonine174 relationship: transforms_into CCO:B0071447 ! TOM1_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0071448 ! TOM1_HUMAN-Phosphoserine180 relationship: transforms_into CCO:B0071449 ! TOM1_HUMAN-Phosphoserine461 relationship: transforms_into CCO:B0071450 ! TOM1_HUMAN-Phosphoserine462 relationship: transforms_into CCO:B0071451 ! TOM1_HUMAN-Phosphoserine464 [Term] id: CCO:B0063279 name: MT1H_HUMAN def: "Metallothionein-1H" [UniProtKB:P80294] synonym: "Metallothionein-0" EXACT [UniProtKB:P80294] synonym: "Metallothionein-IH" EXACT [UniProtKB:P80294] synonym: "MT-0" EXACT [UniProtKB:P80294] synonym: "MT-1H" EXACT [UniProtKB:P80294] synonym: "MT-IH" EXACT [UniProtKB:P80294] xref: EMBL:AAB30081.1 xref: EMBL:AAH08408.1 xref: EMBL:AAH59780.1 xref: EMBL:AAP35835.1 xref: EMBL:CAA45516.1 xref: EMBL:CAA46046.1 xref: UniProtKB:P80294 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022408 ! MT1H_human relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006255 ! cadmium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018574 ! dnajc1-mt1h-1 physical interaction relationship: transforms_into CCO:B0068302 ! MT1H_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0063280 name: MYOTI_HUMAN def: "Myotilin" [UniProtKB:Q9UBF9] synonym: "57 kDa cytoskeletal protein" EXACT [UniProtKB:Q9UBF9] synonym: "Myofibrillar titin-like Ig domains protein" EXACT [UniProtKB:Q9UBF9] synonym: "Titin immunoglobulin domain protein" EXACT [UniProtKB:Q9UBF9] xref: EMBL:AAD29051.2 xref: EMBL:AAD44754.1 xref: EMBL:AAH05376.1 xref: UniProtKB:A0A4R6 xref: UniProtKB:Q9UBF9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022423 ! MYOT_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0018576 ! st7-ttid-1 physical interaction [Term] id: CCO:B0063281 name: DOCK2_HUMAN def: "Dedicator of cytokinesis protein 2" [UniProtKB:Q92608] xref: EMBL:AAH16996.1 xref: EMBL:AAI04901.1 xref: EMBL:AAI13458.1 xref: EMBL:BAA13200.1 xref: UniProtKB:Q2M3I0 xref: UniProtKB:Q92608 xref: UniProtKB:Q96AK7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022193 ! DOCK2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018592 ! rac1-dock2-1 physical interaction relationship: transforms_into CCO:B0065956 ! DOCK2_HUMAN-Phosphotyrosine209 relationship: transforms_into CCO:B0065957 ! DOCK2_HUMAN-Phosphotyrosine212 relationship: transforms_into CCO:B0065958 ! DOCK2_HUMAN-Phosphoserine1706 [Term] id: CCO:B0063282 name: GEMI2_HUMAN def: "Survival of motor neuron protein-interacting protein 1" [UniProtKB:O14893] synonym: "Component of gems 2" EXACT [UniProtKB:O14893] synonym: "Gemin-2" EXACT [UniProtKB:O14893] synonym: "SMN-interacting protein 1" EXACT [UniProtKB:O14893] xref: EMBL:AAB82297.1 xref: EMBL:AAI04969.1 xref: EMBL:BAB03508.1 xref: EMBL:BAB03509.1 xref: EMBL:BAB03510.1 xref: EMBL:CAC16117.2 xref: UniProtKB:O14893 xref: UniProtKB:Q2M3B3 xref: UniProtKB:Q9H4F5 xref: UniProtKB:Q9NS77 xref: UniProtKB:Q9NS78 xref: UniProtKB:Q9NS79 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022271 ! SIP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018600 ! gemin5-gemin4-1 physical interaction relationship: transforms_into CCO:B0066440 ! GEMI2_HUMAN-Phosphothreonine48 [Term] id: CCO:B0063283 name: TRM61_HUMAN def: "tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61" [UniProtKB:Q96FX7] synonym: "EC 2.1.1.36" EXACT [UniProtKB:Q96FX7] synonym: "tRNA(m1A58)-methyltransferase subunit TRM61" EXACT [UniProtKB:Q96FX7] synonym: "tRNA(m1A58)MTase subunit TRM61" EXACT [UniProtKB:Q96FX7] xref: EMBL:AAH10167.1 xref: EMBL:BAC05168.1 xref: UniProtKB:A6NN78 xref: UniProtKB:Q8N7Q9 xref: UniProtKB:Q96FX7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022739 ! TRM61_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018633 ! trm61-trm6-1 physical interaction relationship: transforms_into CCO:B0071580 ! TRM61_HUMAN-Phosphoserine2 relationship: transforms_into CCO:B0071581 ! TRM61_HUMAN-Phosphoserine19 [Term] id: CCO:B0063284 name: GYS1_HUMAN def: "Glycogen [starch] synthase, muscle" [UniProtKB:P13807] synonym: "EC 2.4.1.11" EXACT [UniProtKB:P13807] xref: EMBL:AAA88046.1 xref: EMBL:AAB60385.1 xref: EMBL:AAH02617.1 xref: EMBL:AAH07688.1 xref: EMBL:CAA83916.1 xref: UniProtKB:P13807 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022291 ! GYS1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000792 ! glycogen (starch) synthase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0018694 ! gsk3b-gys-1 phosphorylation relationship: transforms_into CCO:B0066666 ! GYS1_HUMAN-Phosphoserine8 relationship: transforms_into CCO:B0066667 ! GYS1_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0066668 ! GYS1_HUMAN-Phosphoserine641 relationship: transforms_into CCO:B0066669 ! GYS1_HUMAN-Phosphoserine645 relationship: transforms_into CCO:B0066670 ! GYS1_HUMAN-Phosphoserine649 relationship: transforms_into CCO:B0066671 ! GYS1_HUMAN-Phosphoserine653 relationship: transforms_into CCO:B0066672 ! GYS1_HUMAN-Phosphoserine657 relationship: transforms_into CCO:B0066673 ! GYS1_HUMAN-Phosphoserine698 relationship: transforms_into CCO:B0066674 ! GYS1_HUMAN-Phosphoserine710 [Term] id: CCO:B0063285 name: RABE1_HUMAN def: "Rab GTPase-binding effector protein 1" [UniProtKB:Q15276] synonym: "Rabaptin-4" EXACT [UniProtKB:Q15276] synonym: "Rabaptin-5" EXACT [UniProtKB:Q15276] synonym: "Rabaptin-5alpha" EXACT [UniProtKB:Q15276] synonym: "Renal carcinoma antigen NY-REN-17" EXACT [UniProtKB:Q15276] xref: EMBL:AAC70781.1 xref: EMBL:AAH41700.1 xref: EMBL:CAA62580.1 xref: UniProtKB:O95369 xref: UniProtKB:Q15276 xref: UniProtKB:Q8IVX3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022554 ! RABEP1_human relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0002022 ! recycling endosome relationship: participates_in CCO:I0018705 ! rab5a-rabep1-1 direct interaction relationship: transforms_into CCO:B0069699 ! RABE1_HUMAN-Phosphoserine407 relationship: transforms_into CCO:B0069700 ! RABE1_HUMAN-Phosphothreonine408 relationship: transforms_into CCO:B0069701 ! RABE1_HUMAN-Phosphoserine410 [Term] id: CCO:B0063286 name: LEG3_HUMAN def: "Galectin-3" [UniProtKB:P17931] synonym: "35 kDa lectin" EXACT [UniProtKB:P17931] synonym: "Carbohydrate-binding protein 35" EXACT [UniProtKB:P17931] synonym: "CBP 35" EXACT [UniProtKB:P17931] synonym: "Galactose-specific lectin 3" EXACT [UniProtKB:P17931] synonym: "Galactoside-binding protein" EXACT [UniProtKB:P17931] synonym: "GALBP" EXACT [UniProtKB:P17931] synonym: "IgE-binding protein" EXACT [UniProtKB:P17931] synonym: "L-31" EXACT [UniProtKB:P17931] synonym: "Laminin-binding protein" EXACT [UniProtKB:P17931] synonym: "Lectin L-29" EXACT [UniProtKB:P17931] synonym: "Mac-2 antigen" EXACT [UniProtKB:P17931] xref: EMBL:AAA35607.1 xref: EMBL:AAA36163.1 xref: EMBL:AAA88086.1 xref: EMBL:AAB26229.1 xref: EMBL:AAB86584.1 xref: EMBL:AAH01120.1 xref: EMBL:AAH53667.1 xref: EMBL:BAA22164.1 xref: UniProtKB:P17931 xref: UniProtKB:Q16005 xref: UniProtKB:Q96J47 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022365 ! LGALS3_human relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0004196 ! IgE binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: transforms_into CCO:B0067610 ! LEG3_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0067611 ! LEG3_HUMAN-Phosphoserine6 relationship: transforms_into CCO:B0067612 ! LEG3_HUMAN-Phosphoserine12 [Term] id: CCO:B0063287 name: G8_HUMAN def: "Protein G8" [UniProtKB:Q9UBA6] xref: EMBL:CAB56506.1 xref: EMBL:CAB56508.1 xref: UniProtKB:Q9UBA6 xref: UniProtKB:Q9UBA8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022266 ! C6orf48_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction [Term] id: CCO:B0063288 name: B3GN9_HUMAN def: "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" [UniProtKB:Q6UX72] synonym: "Beta-1,3-N-acetylglucosaminyltransferase-9" EXACT [UniProtKB:Q6UX72] synonym: "Beta3Gn-T9" EXACT [UniProtKB:Q6UX72] synonym: "BGnT-9" EXACT [UniProtKB:Q6UX72] synonym: "EC 2.4.1.-" EXACT [UniProtKB:Q6UX72] xref: EMBL:AAH12191.1 xref: EMBL:AAQ88849.1 xref: EMBL:EAW83079.1 xref: UniProtKB:Q6UX72 xref: UniProtKB:Q96EK0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022064 ! B3GNT9_human relationship: has_function CCO:F0001853 ! galactosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction [Term] id: CCO:B0063289 name: CH055_HUMAN def: "UPF0670 protein C8orf55 precursor" [UniProtKB:Q8WUY1] synonym: "Mesenchymal stem cell protein DSCD75" EXACT [UniProtKB:Q8WUY1] xref: EMBL:AAF65450.1 xref: EMBL:AAH01311.1 xref: EMBL:AAH19104.1 xref: EMBL:BAC11600.1 xref: EMBL:BAG37983.1 xref: UniProtKB:B2RDN6 xref: UniProtKB:Q8NBN2 xref: UniProtKB:Q8WUY1 xref: UniProtKB:Q9NYI2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022120 ! C8orf55_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007478 ! cftr-ebp physical interaction relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction [Term] id: CCO:B0063290 name: XPP3_HUMAN def: "Probable Xaa-Pro aminopeptidase 3" [UniProtKB:Q9NQH7] synonym: "Aminopeptidase P3" EXACT [UniProtKB:Q9NQH7] synonym: "APP3" EXACT [UniProtKB:Q9NQH7] synonym: "EC 3.4.11.9" EXACT [UniProtKB:Q9NQH7] synonym: "X-Pro aminopeptidase 3" EXACT [UniProtKB:Q9NQH7] xref: EMBL:AAH01208.1 xref: EMBL:AAH01681.1 xref: EMBL:AAH04989.1 xref: EMBL:CAB97210.1 xref: EMBL:CAD38980.1 xref: EMBL:CAG30328.1 xref: EMBL:CAG33677.1 xref: EMBL:CAI19023.1 xref: EMBL:CAI20492.1 xref: UniProtKB:Q6I9V9 xref: UniProtKB:Q8NDA6 xref: UniProtKB:Q9BV27 xref: UniProtKB:Q9BVH0 xref: UniProtKB:Q9NQH7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022789 ! XPNPEP3_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001785 ! metalloexopeptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001914 ! X-Pro aminopeptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction [Term] id: CCO:B0063291 name: ZO3_HUMAN def: "Tight junction protein ZO-3" [UniProtKB:O95049] synonym: "Tight junction protein 3" EXACT [UniProtKB:O95049] synonym: "Zona occludens protein 3" EXACT [UniProtKB:O95049] synonym: "Zonula occludens protein 3" EXACT [UniProtKB:O95049] xref: EMBL:AAC72274.1 xref: EMBL:EAW69293.1 xref: UniProtKB:A6NFP3 xref: UniProtKB:O95049 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022827 ! TJP3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: transforms_into CCO:B0072272 ! ZO3_HUMAN-Phosphoserine159 relationship: transforms_into CCO:B0072273 ! ZO3_HUMAN-Phosphoserine164 relationship: transforms_into CCO:B0072274 ! ZO3_HUMAN-Phosphoserine169 relationship: transforms_into CCO:B0072275 ! ZO3_HUMAN-Phosphoserine579 relationship: transforms_into CCO:B0072276 ! ZO3_HUMAN-Phosphoserine919 relationship: transforms_into CCO:B0072277 ! ZO3_HUMAN-Phosphoserine920 [Term] id: CCO:B0063292 name: SAP_HUMAN def: "Proactivator polypeptide precursor" [UniProtKB:P07602] xref: EMBL:AAA36594.1 xref: EMBL:AAA36595.1 xref: EMBL:AAA36596.1 xref: EMBL:AAA52560.1 xref: EMBL:AAA60303.1 xref: EMBL:AAB59494.1 xref: EMBL:AAH01503.1 xref: EMBL:AAH04275.1 xref: EMBL:AAH07612.1 xref: EMBL:BAA00321.1 xref: EMBL:CAA40391.1 xref: EMBL:CAA40392.1 xref: EMBL:CAG33027.1 xref: UniProtKB:P07292 xref: UniProtKB:P07602 xref: UniProtKB:P15793 xref: UniProtKB:P78538 xref: UniProtKB:P78541 xref: UniProtKB:P78546 xref: UniProtKB:P78547 xref: UniProtKB:P78558 xref: UniProtKB:Q6IBQ6 xref: UniProtKB:Q92739 xref: UniProtKB:Q92740 xref: UniProtKB:Q92741 xref: UniProtKB:Q92742 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022636 ! PSAP_human relationship: has_function CCO:F0000571 ! cerebroside-sulfatase activity relationship: has_function CCO:F0000755 ! galactosylceramidase activity relationship: has_function CCO:F0000767 ! glucosylceramidase activity relationship: has_function CCO:F0000942 ! alpha-galactosidase activity relationship: has_function CCO:F0000949 ! beta-galactosidase activity relationship: has_function CCO:F0001127 ! sphingomyelin phosphodiesterase activity relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction relationship: participates_in CCO:I0020273 ! celsr1-psap physical interaction relationship: participates_in CCO:I0020361 ! maff-psap physical interaction [Term] id: CCO:B0063293 name: LIN7C_HUMAN def: "Lin-7 homolog C" [UniProtKB:Q9NUP9] synonym: "Lin-7C" EXACT [UniProtKB:Q9NUP9] synonym: "MALS-3" EXACT [UniProtKB:Q9NUP9] synonym: "Mammalian lin-seven protein 3" EXACT [UniProtKB:Q9NUP9] synonym: "Veli-3 protein" EXACT [UniProtKB:Q9NUP9] synonym: "Vertebrate lin-7 homolog 3" EXACT [UniProtKB:Q9NUP9] xref: EMBL:AAH53907.1 xref: EMBL:BAA92072.1 xref: UniProtKB:Q9NUP9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022371 ! LIN7C_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: participates_in CCO:I0007479 ! cftr-atp2a2 physical interaction [Term] id: CCO:B0063294 name: IL1RA_HUMAN def: "Interleukin-1 receptor antagonist protein precursor" [UniProtKB:P18510] synonym: "Anakinra" EXACT [UniProtKB:P18510] synonym: "ICIL-1RA" EXACT [UniProtKB:P18510] synonym: "IL-1ra" EXACT [UniProtKB:P18510] synonym: "IL-1RN" EXACT [UniProtKB:P18510] synonym: "IL1 inhibitor" EXACT [UniProtKB:P18510] synonym: "IRAP" EXACT [UniProtKB:P18510] xref: EMBL:AAA59138.1 xref: EMBL:AAB41943.1 xref: EMBL:AAB92268.1 xref: EMBL:AAB92269.1 xref: EMBL:AAB92270.1 xref: EMBL:AAC39672.1 xref: EMBL:AAH09745.1 xref: EMBL:AAN87150.1 xref: EMBL:CAA36262.1 xref: EMBL:CAA37386.1 xref: EMBL:CAA45832.1 xref: EMBL:CAA59087.1 xref: EMBL:CAD29879.1 xref: UniProtKB:P18510 xref: UniProtKB:Q14628 xref: UniProtKB:Q7RTZ4 xref: UniProtKB:Q96GD6 xref: UniProtKB:Q9UPC0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022336 ! IL1RN_human relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001451 ! interleukin-1 receptor binding relationship: has_function CCO:F0001454 ! interleukin-1 receptor antagonist activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018739 ! il1r1-il1rn-1 direct interaction [Term] id: CCO:B0063295 name: PEPL_HUMAN def: "Periplakin" [UniProtKB:O60437] synonym: "190 kDa paraneoplastic pemphigus antigen" EXACT [UniProtKB:O60437] synonym: "195 kDa cornified envelope precursor protein" EXACT [UniProtKB:O60437] xref: EMBL:AAC17738.1 xref: EMBL:AAC39668.1 xref: EMBL:AAD17459.1 xref: EMBL:BAA25494.1 xref: UniProtKB:O60314 xref: UniProtKB:O60437 xref: UniProtKB:O60454 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022503 ! PPL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018768 ! ppl-akt1-2 physical interaction relationship: transforms_into CCO:B0069211 ! PEPL_HUMAN-Phosphoserine1331 relationship: transforms_into CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 [Term] id: CCO:B0063296 name: EXOC2_HUMAN def: "Exocyst complex component 2" [UniProtKB:Q96KP1] synonym: "Exocyst complex component Sec5" EXACT [UniProtKB:Q96KP1] xref: EMBL:AAH16918.2 xref: EMBL:AAH80542.1 xref: EMBL:BAA91963.1 xref: EMBL:CAC92092.1 xref: EMBL:CAH70772.1 xref: EMBL:CAI19790.1 xref: EMBL:CAI46189.1 xref: UniProtKB:Q5JPC8 xref: UniProtKB:Q96AN6 xref: UniProtKB:Q96KP1 xref: UniProtKB:Q9NUZ8 xref: UniProtKB:Q9UJM7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022229 ! EXOC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018776 ! sec5-gnefr-1 physical interaction relationship: transforms_into CCO:B0066030 ! EXOC2_HUMAN-Phosphoserine432 relationship: transforms_into CCO:B0066031 ! EXOC2_HUMAN-Phosphoserine435 [Term] id: CCO:B0063297 name: PGTB2_HUMAN def: "Geranylgeranyl transferase type-2 subunit beta" [UniProtKB:P53611] synonym: "EC 2.5.1.60" EXACT [UniProtKB:P53611] synonym: "Geranylgeranyl transferase type II subunit beta" EXACT [UniProtKB:P53611] synonym: "GGTase-II-beta" EXACT [UniProtKB:P53611] synonym: "Rab geranyl-geranyltransferase subunit beta" EXACT [UniProtKB:P53611] synonym: "Rab geranylgeranyltransferase subunit beta" EXACT [UniProtKB:P53611] synonym: "Rab GG transferase beta" EXACT [UniProtKB:P53611] synonym: "Rab GGTase beta" EXACT [UniProtKB:P53611] synonym: "Type II protein geranyl-geranyltransferase subunit beta" EXACT [UniProtKB:P53611] xref: EMBL:AAA91473.1 xref: EMBL:AAH20790.1 xref: EMBL:CAA66638.1 xref: EMBL:CAA69383.1 xref: UniProtKB:P53611 xref: UniProtKB:Q92697 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022509 ! RABGGTB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018799 ! araf-rabggtb physical interaction relationship: participates_in CCO:I0018803 ! araf-rabggtb-1 physical interaction relationship: participates_in CCO:I0018814 ! araf-rabggtb-2 physical interaction relationship: transforms_into CCO:B0069244 ! PGTB2_HUMAN-Phosphothreonine3 [Term] id: CCO:B0063298 name: PPLA_HUMAN def: "Cardiac phospholamban" [UniProtKB:P26678] synonym: "PLB" EXACT [UniProtKB:P26678] xref: EMBL:AAA60083.1 xref: EMBL:AAA60109.1 xref: EMBL:AAD55950.1 xref: EMBL:AAH05269.1 xref: UniProtKB:P26678 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022525 ! PLN_human relationship: has_function CCO:F0001514 ! calcium channel regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005613 ! ATPase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000802 ! sarcoplasmic reticulum relationship: participates_in CCO:I0018835 ! dmpk-pln-3 phosphorylation relationship: participates_in CCO:I0018836 ! dmpk-pln-4 phosphorylation relationship: participates_in CCO:I0019261 ! dmpk-pln-1 phosphorylation relationship: participates_in CCO:I0019262 ! dmpk-pln-2 phosphorylation relationship: transforms_into CCO:B0069457 ! PPLA_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0069458 ! PPLA_HUMAN-Phosphoserine16 relationship: transforms_into CCO:B0069459 ! PPLA_HUMAN-Phosphothreonine17 [Term] id: CCO:B0063299 name: SNTB2_HUMAN def: "Beta-2-syntrophin" [UniProtKB:Q13425] synonym: "59 kDa dystrophin-associated protein A1 basic component 2" EXACT [UniProtKB:Q13425] synonym: "SNT3" EXACT [UniProtKB:Q13425] synonym: "SNTL" EXACT [UniProtKB:Q13425] synonym: "Syntrophin-3" EXACT [UniProtKB:Q13425] synonym: "Syntrophin-like" EXACT [UniProtKB:Q13425] xref: EMBL:AAC50449.1 xref: EMBL:AAH48215.1 xref: EMBL:AAK15149.1 xref: UniProtKB:Q13425 xref: UniProtKB:Q9BY09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022664 ! SNTB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018858 ! erbb4-sntb2-1 physical interaction relationship: transforms_into CCO:B0070705 ! SNTB2_HUMAN-Phosphoserine95 relationship: transforms_into CCO:B0070706 ! SNTB2_HUMAN-Phosphoserine110 relationship: transforms_into CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: transforms_into CCO:B0070708 ! SNTB2_HUMAN-Phosphoserine222 relationship: transforms_into CCO:B0070709 ! SNTB2_HUMAN-Phosphoserine233 relationship: transforms_into CCO:B0070710 ! SNTB2_HUMAN-Phosphoserine393 [Term] id: CCO:B0063300 name: TSSK6_HUMAN def: "Testis-specific serine/threonine-protein kinase 6" [UniProtKB:Q9BXA6] synonym: "Cancer/testis antigen 72" EXACT [UniProtKB:Q9BXA6] synonym: "CT72" EXACT [UniProtKB:Q9BXA6] synonym: "EC 2.7.11.1" EXACT [UniProtKB:Q9BXA6] synonym: "Serine/threonine-protein kinase SSTK" EXACT [UniProtKB:Q9BXA6] synonym: "Small serine/threonine kinase" EXACT [UniProtKB:Q9BXA6] synonym: "TSSK-6" EXACT [UniProtKB:Q9BXA6] xref: EMBL:AAH14611.1 xref: EMBL:AAK29414.1 xref: EMBL:AAK48827.1 xref: EMBL:BAB71697.1 xref: EMBL:BAD18805.1 xref: UniProtKB:Q6ZMC4 xref: UniProtKB:Q96LJ4 xref: UniProtKB:Q9BXA6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022745 ! TSSK6_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018863 ! tssk6-hspcb-2 physical interaction relationship: participates_in CCO:I0019509 ! tssk6-hspcb-1 physical interaction [Term] id: CCO:B0063301 name: STXB1_HUMAN def: "Syntaxin-binding protein 1" [UniProtKB:P61764] synonym: "N-Sec1" EXACT [UniProtKB:P61764] synonym: "p67" EXACT [UniProtKB:P61764] synonym: "Unc-18 homolog" EXACT [UniProtKB:P61764] synonym: "Unc-18-1" EXACT [UniProtKB:P61764] synonym: "Unc-18A" EXACT [UniProtKB:P61764] xref: EMBL:AAC39688.1 xref: EMBL:AAC39689.1 xref: EMBL:AAH15749.1 xref: EMBL:BAA19483.1 xref: UniProtKB:P61764 xref: UniProtKB:Q28208 xref: UniProtKB:Q62759 xref: UniProtKB:Q64320 xref: UniProtKB:Q96TG8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022684 ! STXBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007604 ! app-nsf-1 physical interaction relationship: transforms_into CCO:B0070987 ! STXB1_HUMAN-Phosphothreonine107 relationship: transforms_into CCO:B0070988 ! STXB1_HUMAN-Phosphoserine142 relationship: transforms_into CCO:B0070989 ! STXB1_HUMAN-Phosphotyrosine145 relationship: transforms_into CCO:B0070990 ! STXB1_HUMAN-Phosphoserine146 relationship: transforms_into CCO:B0070991 ! STXB1_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0070992 ! STXB1_HUMAN-Phosphothreonine346 relationship: transforms_into CCO:B0070993 ! STXB1_HUMAN-Phosphotyrosine473 relationship: transforms_into CCO:B0070994 ! STXB1_HUMAN-Phosphoserine507 relationship: transforms_into CCO:B0070995 ! STXB1_HUMAN-Phosphoserine509 [Term] id: CCO:B0063302 name: PTN2_HUMAN def: "Tyrosine-protein phosphatase non-receptor type 2" [UniProtKB:P17706] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P17706] synonym: "T-cell protein-tyrosine phosphatase" EXACT [UniProtKB:P17706] synonym: "TCPTP" EXACT [UniProtKB:P17706] xref: EMBL:AAA65997.1 xref: EMBL:AAH08244.1 xref: UniProtKB:P17706 xref: UniProtKB:Q96HR2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022541 ! PTPN2_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018879 ! wasl-ptpn2-1 dephosphorylation relationship: participates_in CCO:I0018880 ! wasl-ptpn2-2 phosphorylation [Term] id: CCO:B0063303 name: VPP2_HUMAN def: "V-type proton ATPase 116 kDa subunit a isoform 2" [UniProtKB:Q9Y487] synonym: "Lysosomal H(+)-transporting ATPase V0 subunit a2" EXACT [UniProtKB:Q9Y487] synonym: "TJ6" EXACT [UniProtKB:Q9Y487] synonym: "V-ATPase 116 kDa isoform a2" EXACT [UniProtKB:Q9Y487] synonym: "Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2" EXACT [UniProtKB:Q9Y487] xref: EMBL:AAD04632.1 xref: EMBL:AAH68531.1 xref: EMBL:BAF82080.1 xref: EMBL:EAW98434.1 xref: UniProtKB:A8K026 xref: UniProtKB:Q6NUM0 xref: UniProtKB:Q9Y487 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022775 ! ATP6V0A2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000177 ! acrosome relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018881 ! pscd2-atp6v0a2-6 physical interaction relationship: participates_in CCO:I0019519 ! pscd2-atp6v0a2-7 physical interaction relationship: transforms_into CCO:B0071813 ! VPP2_HUMAN-Phosphoserine177 relationship: transforms_into CCO:B0071814 ! VPP2_HUMAN-Phosphoserine695 relationship: transforms_into CCO:B0071815 ! VPP2_HUMAN-Phosphoserine700 relationship: transforms_into CCO:B0071816 ! VPP2_HUMAN-Phosphoserine704 [Term] id: CCO:B0063304 name: CE350_HUMAN def: "Centrosome-associated protein 350" [UniProtKB:Q5VT06] synonym: "Centrosome-associated protein of 350 kDa" EXACT [UniProtKB:Q5VT06] synonym: "Cep350" EXACT [UniProtKB:Q5VT06] xref: EMBL:AAL55733.1 xref: EMBL:AAL91355.1 xref: EMBL:CAH72345.1 xref: EMBL:CAI14833.1 xref: EMBL:CAI15177.1 xref: UniProtKB:O75068 xref: UniProtKB:Q5VT06 xref: UniProtKB:Q8TDK3 xref: UniProtKB:Q8WY20 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022112 ! CEP350_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018909 ! aptx-cep350 physical interaction relationship: transforms_into CCO:B0065847 ! CE350_HUMAN-Phosphothreonine878 relationship: transforms_into CCO:B0065848 ! CE350_HUMAN-Phosphothreonine1253 relationship: transforms_into CCO:B0065849 ! CE350_HUMAN-Phosphoserine1256 relationship: transforms_into CCO:B0065850 ! CE350_HUMAN-Phosphoserine1259 relationship: transforms_into CCO:B0065851 ! CE350_HUMAN-Phosphoserine1818 relationship: transforms_into CCO:B0065852 ! CE350_HUMAN-Phosphothreonine2204 relationship: transforms_into CCO:B0065853 ! CE350_HUMAN-Phosphoserine2206 relationship: transforms_into CCO:B0065854 ! CE350_HUMAN-Phosphoserine2460 [Term] id: CCO:B0063305 name: VTM2L_HUMAN def: "V-set and transmembrane domain-containing protein 2-like protein precursor" [UniProtKB:Q96N03] xref: EMBL:AAH33818.1 xref: EMBL:BAB71113.1 xref: EMBL:CAD39072.2 xref: EMBL:CAI42205.1 xref: EMBL:CAI42206.2 xref: EMBL:CAI42207.1 xref: UniProtKB:Q5JWZ4 xref: UniProtKB:Q5JWZ5 xref: UniProtKB:Q8ND45 xref: UniProtKB:Q96N03 xref: UniProtKB:Q9BR37 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022780 ! VSTM2L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018945 ! atxn1-c20orf102 physical interaction relationship: participates_in CCO:I0018966 ! atxn1-c20orf102-1 physical interaction relationship: participates_in CCO:I0019023 ! atxn1-c20orf102-2 physical interaction [Term] id: CCO:B0063306 name: Z804A_HUMAN def: "Zinc finger protein 804A" [UniProtKB:Q7Z570] xref: EMBL:AAP92799.1 xref: EMBL:BAD18549.1 xref: UniProtKB:Q6ZN26 xref: UniProtKB:Q7Z570 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022796 ! ZNF804A_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0018946 ! atxn1-c2orf10 physical interaction relationship: participates_in CCO:I0019024 ! atxn1-c2orf10-1 physical interaction [Term] id: CCO:B0063307 name: CLC4F_HUMAN def: "C-type lectin domain family 4 member F" [UniProtKB:Q8N1N0] synonym: "C-type lectin 13" EXACT [UniProtKB:Q8N1N0] synonym: "C-type lectin superfamily member 13" EXACT [UniProtKB:Q8N1N0] xref: EMBL:BAC04786.1 xref: UniProtKB:Q8N1N0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022135 ! CLEC4F_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0018949 ! atxn1-clec4f physical interaction relationship: participates_in CCO:I0019087 ! atxn1-clec4f-1 physical interaction [Term] id: CCO:B0063308 name: FPPS_HUMAN def: "Farnesyl pyrophosphate synthetase" [UniProtKB:P14324] synonym: "Farnesyl diphosphate synthetase" EXACT [UniProtKB:P14324] synonym: "FPP synthetase" EXACT [UniProtKB:P14324] synonym: "FPS" EXACT [UniProtKB:P14324] xref: EMBL:AAA35820.1 xref: EMBL:AAA52423.1 xref: EMBL:AAH10004.1 xref: EMBL:BAA03523.2 xref: EMBL:BAF83773.1 xref: EMBL:CAI12715.1 xref: EMBL:EAW53076.1 xref: UniProtKB:P14324 xref: UniProtKB:Q96G29 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022260 ! FDPS_human relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018951 ! atxn1-fdps physical interaction [Term] id: CCO:B0063309 name: GPTC8_HUMAN def: "G patch domain-containing protein 8" [UniProtKB:Q9UKJ3] xref: EMBL:AAF03681.1 xref: EMBL:BAA25479.2 xref: UniProtKB:O60300 xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022288 ! GPATCH8_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018954 ! atxn1-kiaa0553 physical interaction relationship: participates_in CCO:I0018976 ! atxn1-kiaa0553-1 physical interaction relationship: participates_in CCO:I0018997 ! atxn1-kiaa0553-2 physical interaction relationship: participates_in CCO:I0019045 ! atxn1-kiaa0553-3 physical interaction relationship: transforms_into CCO:B0066558 ! GPTC8_HUMAN-Phosphoserine86 relationship: transforms_into CCO:B0066559 ! GPTC8_HUMAN-Phosphoserine237 relationship: transforms_into CCO:B0066560 ! GPTC8_HUMAN-Phosphothreonine242 relationship: transforms_into CCO:B0066561 ! GPTC8_HUMAN-Phosphoserine325 relationship: transforms_into CCO:B0066562 ! GPTC8_HUMAN-Phosphoserine327 relationship: transforms_into CCO:B0066563 ! GPTC8_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0066564 ! GPTC8_HUMAN-Phosphoserine498 relationship: transforms_into CCO:B0066565 ! GPTC8_HUMAN-Phosphoserine501 relationship: transforms_into CCO:B0066566 ! GPTC8_HUMAN-Phosphoserine596 relationship: transforms_into CCO:B0066567 ! GPTC8_HUMAN-Phosphoserine601 relationship: transforms_into CCO:B0066568 ! GPTC8_HUMAN-Phosphotyrosine618 relationship: transforms_into CCO:B0066569 ! GPTC8_HUMAN-Phosphoserine620 relationship: transforms_into CCO:B0066570 ! GPTC8_HUMAN-Phosphoserine622 relationship: transforms_into CCO:B0066571 ! GPTC8_HUMAN-Phosphoserine663 relationship: transforms_into CCO:B0066572 ! GPTC8_HUMAN-Phosphoserine668 relationship: transforms_into CCO:B0066573 ! GPTC8_HUMAN-Phosphoserine694 relationship: transforms_into CCO:B0066574 ! GPTC8_HUMAN-Phosphothreonine702 [Term] id: CCO:B0063310 name: Q96D80_HUMAN def: "cDNA FLJ34055 fis, clone FCBBF3000229, highly similar to Syntabulin" [UniProtKB:Q96D80] synonym: "GOLSYN protein" EXACT [UniProtKB:Q96D80] xref: EMBL:AAH12082.1 xref: EMBL:BAG52343.1 xref: UniProtKB:Q96D80 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022852 ! GOLSYN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018971 ! atxn1-q96d80 physical interaction relationship: participates_in CCO:I0019075 ! atxn1-q96d80-1 physical interaction relationship: participates_in CCO:I0019093 ! atxn1-q96d80-2 physical interaction [Term] id: CCO:B0063311 name: SMS1_HUMAN def: "Phosphatidylcholine:ceramide cholinephosphotransferase 1" [UniProtKB:Q86VZ5] synonym: "EC 2.7.8.27" EXACT [UniProtKB:Q86VZ5] synonym: "Medulla oblongata-derived protein" EXACT [UniProtKB:Q86VZ5] synonym: "Protein Mob" EXACT [UniProtKB:Q86VZ5] synonym: "Sphingomyelin synthase 1" EXACT [UniProtKB:Q86VZ5] synonym: "Transmembrane protein 23" EXACT [UniProtKB:Q86VZ5] xref: EMBL:AAH42899.1 xref: EMBL:AAP37279.1 xref: EMBL:AAQ22363.1 xref: EMBL:AAQ82051.1 xref: EMBL:AAR13294.1 xref: EMBL:BAD16809.1 xref: EMBL:CAD79708.1 xref: UniProtKB:Q68U43 xref: UniProtKB:Q6EKK0 xref: UniProtKB:Q75SP1 xref: UniProtKB:Q86VZ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022657 ! SGMS1_human relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005071 ! sphingomyelin synthase activity relationship: has_function CCO:F0006799 ! ceramide cholinephosphotransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000020 ! Golgi trans cisterna relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000988 ! integral to Golgi membrane relationship: participates_in CCO:I0018983 ! atxn1-tmem23 physical interaction [Term] id: CCO:B0063312 name: TTC19_HUMAN def: "Tetratricopeptide repeat protein 19" [UniProtKB:Q6DKK2] synonym: "TPR repeat protein 19" EXACT [UniProtKB:Q6DKK2] xref: EMBL:AAH11698.2 xref: EMBL:AAH73796.1 xref: EMBL:AAI05129.1 xref: EMBL:AAI12108.1 xref: EMBL:BAA91103.1 xref: EMBL:BAG51820.1 xref: UniProtKB:Q2M248 xref: UniProtKB:Q6DKK2 xref: UniProtKB:Q7L3U8 xref: UniProtKB:Q9NXB2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022746 ! TTC19_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0018984 ! atxn1-ttc19 physical interaction [Term] id: CCO:B0063313 name: ATX2L_HUMAN def: "Ataxin-2-like protein" [UniProtKB:Q8WWM7] synonym: "Ataxin-2 domain protein" EXACT [UniProtKB:Q8WWM7] synonym: "Ataxin-2-related protein" EXACT [UniProtKB:Q8WWM7] xref: EMBL:AAB19201.1 xref: EMBL:AAC69607.1 xref: EMBL:AAH10239.1 xref: EMBL:AAH68012.1 xref: EMBL:AAO12056.1 xref: EMBL:AAO12057.1 xref: EMBL:AAO12058.1 xref: EMBL:AAO12059.1 xref: EMBL:AAO12060.1 xref: EMBL:CAC38068.1 xref: EMBL:CAC38069.3 xref: EMBL:CAC38070.3 xref: EMBL:CAC38071.3 xref: EMBL:CAC38072.3 xref: UniProtKB:O95135 xref: UniProtKB:Q6NVJ8 xref: UniProtKB:Q6PJW6 xref: UniProtKB:Q8IU61 xref: UniProtKB:Q8IU95 xref: UniProtKB:Q8WWM3 xref: UniProtKB:Q8WWM4 xref: UniProtKB:Q8WWM5 xref: UniProtKB:Q8WWM6 xref: UniProtKB:Q8WWM7 xref: UniProtKB:Q99703 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022062 ! ATXN2L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0018989 ! atxn1-atxn2l physical interaction relationship: participates_in CCO:I0019020 ! atxn1-atxn2l-1 physical interaction relationship: transforms_into CCO:B0065766 ! ATX2L_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0065767 ! ATX2L_HUMAN-Phosphoserine111 relationship: transforms_into CCO:B0065768 ! ATX2L_HUMAN-Phosphotyrosine264 relationship: transforms_into CCO:B0065769 ! ATX2L_HUMAN-Phosphotyrosine309 relationship: transforms_into CCO:B0065770 ! ATX2L_HUMAN-Phosphoserine335 relationship: transforms_into CCO:B0065771 ! ATX2L_HUMAN-Phosphoserine339 relationship: transforms_into CCO:B0065772 ! ATX2L_HUMAN-Phosphoserine341 relationship: transforms_into CCO:B0065773 ! ATX2L_HUMAN-Phosphotyrosine349 relationship: transforms_into CCO:B0065774 ! ATX2L_HUMAN-Omega-N-methylated arginine361 relationship: transforms_into CCO:B0065775 ! ATX2L_HUMAN-Phosphoserine390 relationship: transforms_into CCO:B0065776 ! ATX2L_HUMAN-Phosphoserine391 relationship: transforms_into CCO:B0065777 ! ATX2L_HUMAN-Phosphoserine409 relationship: transforms_into CCO:B0065778 ! ATX2L_HUMAN-Phosphoserine449 relationship: transforms_into CCO:B0065779 ! ATX2L_HUMAN-Phosphoserine493 relationship: transforms_into CCO:B0065780 ! ATX2L_HUMAN-Phosphoserine496 relationship: transforms_into CCO:B0065781 ! ATX2L_HUMAN-Phosphoserine557 relationship: transforms_into CCO:B0065782 ! ATX2L_HUMAN-Phosphoserine558 relationship: transforms_into CCO:B0065783 ! ATX2L_HUMAN-Phosphoserine559 relationship: transforms_into CCO:B0065784 ! ATX2L_HUMAN-Phosphoserine563 relationship: transforms_into CCO:B0065785 ! ATX2L_HUMAN-Phosphoserine589 relationship: transforms_into CCO:B0065786 ! ATX2L_HUMAN-Phosphoserine594 relationship: transforms_into CCO:B0065787 ! ATX2L_HUMAN-Phosphoserine597 relationship: transforms_into CCO:B0065788 ! ATX2L_HUMAN-Phosphoserine598 relationship: transforms_into CCO:B0065789 ! ATX2L_HUMAN-Phosphoserine630 relationship: transforms_into CCO:B0065790 ! ATX2L_HUMAN-Phosphoserine634 relationship: transforms_into CCO:B0065791 ! ATX2L_HUMAN-Phosphoserine684 [Term] id: CCO:B0063314 name: HSN2_HUMAN def: "Protein HSN2 precursor" [UniProtKB:Q6IFS5] xref: EMBL:AAI30468.1 xref: EMBL:AAI30470.1 xref: EMBL:DAA04494.1 xref: UniProtKB:A1L4B0 xref: UniProtKB:Q6IFS5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022321 ! HSN2_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0018996 ! atxn1-hsn2 physical interaction [Term] id: CCO:B0063315 name: SAPS2_HUMAN def: "SAPS domain family member 2" [UniProtKB:O75170] xref: EMBL:AAH00976.2 xref: EMBL:BAA31660.2 xref: EMBL:CAO03456.1 xref: EMBL:CAO03458.1 xref: EMBL:CAO03561.1 xref: EMBL:CAO03563.1 xref: EMBL:CAO03642.1 xref: EMBL:CAO03644.1 xref: UniProtKB:A6PVG3 xref: UniProtKB:O75170 xref: UniProtKB:Q7Z5G5 xref: UniProtKB:Q9UGB9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022635 ! SAPS2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0018998 ! atxn1-kiaa0685 physical interaction relationship: participates_in CCO:I0019046 ! atxn1-kiaa0685-1 physical interaction [Term] id: CCO:B0063316 name: R3HD2_HUMAN def: "R3H domain-containing protein 2" [UniProtKB:Q9Y2K5] xref: EMBL:AAH41857.1 xref: EMBL:AAI04996.2 xref: EMBL:AAI12227.2 xref: EMBL:BAA76846.2 xref: UniProtKB:Q2M1T9 xref: UniProtKB:Q3ZCT5 xref: UniProtKB:Q9Y2K5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022552 ! R3HDM2_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0018999 ! atxn1-r3hdm2 physical interaction relationship: participates_in CCO:I0019047 ! atxn1-r3hdm2-1 physical interaction [Term] id: CCO:B0063317 name: MTER2_HUMAN def: "mTERF domain-containing protein 2" [UniProtKB:Q7Z6M4] xref: EMBL:AAF28919.1 xref: EMBL:AAH53533.2 xref: UniProtKB:Q7Z6M4 xref: UniProtKB:Q9P0E0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022409 ! MTERFD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019002 ! atxn1-mterfd2 physical interaction [Term] id: CCO:B0063318 name: OAZ1_HUMAN def: "Ornithine decarboxylase antizyme" [UniProtKB:P54368] synonym: "ODC-Az" EXACT [UniProtKB:P54368] xref: EMBL:AAA82154.1 xref: EMBL:AAA82155.1 xref: EMBL:AAC02802.1 xref: EMBL:AAC02803.1 xref: EMBL:AAW56074.1 xref: EMBL:BAA11373.1 xref: EMBL:BAA11374.1 xref: EMBL:BAA13497.1 xref: EMBL:BAA23101.1 xref: UniProtKB:O43382 xref: UniProtKB:P54368 xref: UniProtKB:Q14989 xref: UniProtKB:Q92595 xref: UniProtKB:Q9UPL9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022471 ! OAZ1_human relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001698 ! ornithine decarboxylase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019003 ! atxn1-oaz1 physical interaction [Term] id: CCO:B0063319 name: Q86UT2_HUMAN def: "RICS protein" [UniProtKB:Q86UT2] xref: EMBL:AAH51236.1 xref: EMBL:AAH65371.1 xref: UniProtKB:Q86UT2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022567 ! RICS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019007 ! atxn1-rics physical interaction relationship: participates_in CCO:I0019058 ! atxn1-rics-1 physical interaction [Term] id: CCO:B0063320 name: ARIP4_HUMAN def: "Helicase ARIP4" [UniProtKB:Q9Y4B4] synonym: "Androgen receptor-interacting protein 4" EXACT [UniProtKB:Q9Y4B4] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9Y4B4] synonym: "RAD54-like protein 2" EXACT [UniProtKB:Q9Y4B4] xref: EMBL:AAH01474.2 xref: EMBL:AAH24298.1 xref: EMBL:BAA34529.2 xref: UniProtKB:Q8TB57 xref: UniProtKB:Q9BV54 xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022047 ! RAD54L2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019010 ! atxn1-kiaa0809 physical interaction relationship: participates_in CCO:I0019062 ! atxn1-kiaa0809-1 physical interaction relationship: transforms_into CCO:B0065745 ! ARIP4_HUMAN-Phosphoserine187 relationship: transforms_into CCO:B0065746 ! ARIP4_HUMAN-Phosphoserine188 relationship: transforms_into CCO:B0065747 ! ARIP4_HUMAN-Phosphoserine189 relationship: transforms_into CCO:B0065748 ! ARIP4_HUMAN-Phosphoserine191 relationship: transforms_into CCO:B0065749 ! ARIP4_HUMAN-Phosphoserine1138 relationship: transforms_into CCO:B0065750 ! ARIP4_HUMAN-Phosphoserine1169 relationship: transforms_into CCO:B0065751 ! ARIP4_HUMAN-Phosphoserine1172 [Term] id: CCO:B0063321 name: CYTC_HUMAN def: "Cystatin-C precursor" [UniProtKB:P01034] synonym: "Cystatin-3" EXACT [UniProtKB:P01034] synonym: "Gamma-trace" EXACT [UniProtKB:P01034] synonym: "Neuroendocrine basic polypeptide" EXACT [UniProtKB:P01034] synonym: "Post-gamma-globulin" EXACT [UniProtKB:P01034] xref: EMBL:AAA52164.1 xref: EMBL:AAH13083.1 xref: EMBL:AAI10306.1 xref: EMBL:AAP35485.1 xref: EMBL:CAA29096.1 xref: EMBL:CAA36497.1 xref: EMBL:CAA43856.2 xref: EMBL:CAC05424.1 xref: EMBL:CAG46785.1 xref: EMBL:CAG46815.1 xref: EMBL:EAX10137.1 xref: UniProtKB:P01034 xref: UniProtKB:Q6FGW9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022168 ! CST3_human relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0019026 ! atxn1-cst3 physical interaction [Term] id: CCO:B0063322 name: ENTP6_HUMAN def: "Ectonucleoside triphosphate diphosphohydrolase 6" [UniProtKB:O75354] synonym: "CD39 antigen-like 2" EXACT [UniProtKB:O75354] synonym: "EC 3.6.1.6" EXACT [UniProtKB:O75354] synonym: "NTPDase 6" EXACT [UniProtKB:O75354] xref: EMBL:AAC39883.1 xref: EMBL:AAH25980.1 xref: EMBL:AAP92131.1 xref: EMBL:CAB41571.1 xref: UniProtKB:O75354 xref: UniProtKB:Q7Z5B5 xref: UniProtKB:Q8TAS7 xref: UniProtKB:Q9UJD1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022220 ! ENTPD6_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003573 ! nucleoside-diphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019033 ! atxn1-entpd6 physical interaction [Term] id: CCO:B0063323 name: Q9NXG9_HUMAN def: "cDNA FLJ20259 fis, clone COLF7443" [UniProtKB:Q9NXG9] xref: EMBL:BAA91042.1 xref: UniProtKB:Q9NXG9 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019037 ! atxn1-q9nxg9 physical interaction [Term] id: CCO:B0063324 name: Q12914_HUMAN def: "Uncharacterized protein C11orf41 (G2)." [UniProtKB:Q12914] xref: EMBL:AAA21253.1 xref: UniProtKB:Q12914 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019039 ! atxn1-g2 physical interaction [Term] id: CCO:B0063325 name: KCAB2_HUMAN def: "Voltage-gated potassium channel subunit beta-2" [UniProtKB:Q13303] synonym: "HKvbeta2" EXACT [UniProtKB:Q13303] synonym: "K(+) channel subunit beta-2" EXACT [UniProtKB:Q13303] synonym: "Kv-beta-2" EXACT [UniProtKB:Q13303] xref: EMBL:AAB84170.1 xref: EMBL:AAB99859.1 xref: EMBL:AAC50955.1 xref: EMBL:AAI26425.1 xref: EMBL:AAI30414.1 xref: EMBL:CAC08512.1 xref: EMBL:CAI19885.1 xref: UniProtKB:A0AVM9 xref: UniProtKB:O43659 xref: UniProtKB:Q13303 xref: UniProtKB:Q5TG82 xref: UniProtKB:Q5TG83 xref: UniProtKB:Q99411 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022348 ! KCNAB2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019044 ! atxn1-kcnab2 physical interaction relationship: transforms_into CCO:B0067264 ! KCAB2_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0067265 ! KCAB2_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0067266 ! KCAB2_HUMAN-Phosphotyrosine25 relationship: transforms_into CCO:B0067267 ! KCAB2_HUMAN-Phosphotyrosine360 [Term] id: CCO:B0063326 name: Q4ZG59_HUMAN def: "Putative uncharacterized protein R3HDM" [UniProtKB:Q4ZG59] xref: EMBL:AAX88922.1 xref: UniProtKB:Q4ZG59 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022833 ! R3HDM_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019056 ! atxn1-r3hdm physical interaction [Term] id: CCO:B0063327 name: UBP2L_HUMAN def: "Ubiquitin-associated protein 2-like" [UniProtKB:Q14157] synonym: "Protein NICE-4" EXACT [UniProtKB:Q14157] xref: EMBL:AAH03170.1 xref: EMBL:BAA09765.1 xref: EMBL:CAB65099.1 xref: EMBL:CAB65101.2 xref: EMBL:CAH71283.1 xref: EMBL:CAH71284.1 xref: EMBL:CAH71285.1 xref: UniProtKB:Q14157 xref: UniProtKB:Q5VU75 xref: UniProtKB:Q5VU76 xref: UniProtKB:Q9BTU3 xref: UniProtKB:Q9UGL2 xref: UniProtKB:Q9UGL3 xref: UniProtKB:Q9UGL5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022761 ! UBAP2L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019066 ! atxn1-ubap2l physical interaction relationship: transforms_into CCO:B0071679 ! UBP2L_HUMAN-Phosphoserine360 relationship: transforms_into CCO:B0071680 ! UBP2L_HUMAN-Phosphoserine416 relationship: transforms_into CCO:B0071681 ! UBP2L_HUMAN-Phosphothreonine419 relationship: transforms_into CCO:B0071682 ! UBP2L_HUMAN-Phosphoserine439 relationship: transforms_into CCO:B0071683 ! UBP2L_HUMAN-Phosphoserine453 relationship: transforms_into CCO:B0071684 ! UBP2L_HUMAN-Phosphoserine454 relationship: transforms_into CCO:B0071685 ! UBP2L_HUMAN-Phosphoserine467 relationship: transforms_into CCO:B0071686 ! UBP2L_HUMAN-Phosphoserine470 relationship: transforms_into CCO:B0071687 ! UBP2L_HUMAN-Phosphoserine471 relationship: transforms_into CCO:B0071688 ! UBP2L_HUMAN-Phosphoserine477 relationship: transforms_into CCO:B0071689 ! UBP2L_HUMAN-Phosphoserine605 relationship: transforms_into CCO:B0071690 ! UBP2L_HUMAN-Phosphoserine607 relationship: transforms_into CCO:B0071691 ! UBP2L_HUMAN-Phosphoserine608 relationship: transforms_into CCO:B0071692 ! UBP2L_HUMAN-Phosphoserine609 relationship: transforms_into CCO:B0071693 ! UBP2L_HUMAN-Phosphotyrosine834 relationship: transforms_into CCO:B0071694 ! UBP2L_HUMAN-Phosphotyrosine835 relationship: transforms_into CCO:B0071695 ! UBP2L_HUMAN-Phosphothreonine844 relationship: transforms_into CCO:B0071696 ! UBP2L_HUMAN-Phosphoserine852 relationship: transforms_into CCO:B0071697 ! UBP2L_HUMAN-Phosphoserine859 [Term] id: CCO:B0063328 name: AHDC1_HUMAN def: "A.T hook DNA-binding motif-containing protein 1" [UniProtKB:Q5TGY3] xref: EMBL:AAB50205.1 xref: EMBL:AAH02677.2 xref: EMBL:AAH14394.3 xref: EMBL:BAC86163.1 xref: EMBL:CAI19618.1 xref: EMBL:CAI19619.1 xref: UniProtKB:Q5TGY3 xref: UniProtKB:Q5TGY4 xref: UniProtKB:Q6PJK1 xref: UniProtKB:Q6ZUQ6 xref: UniProtKB:Q99769 xref: UniProtKB:Q9NUF5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022028 ! AHDC1_human relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019074 ! atxn1-rp1_159a19_1 physical interaction relationship: participates_in CCO:I0019090 ! atxn1-rp1_159a19_1-1 physical interaction relationship: transforms_into CCO:B0065488 ! AHDC1_HUMAN-Phosphoserine70 relationship: transforms_into CCO:B0065489 ! AHDC1_HUMAN-Phosphoserine829 relationship: transforms_into CCO:B0065490 ! AHDC1_HUMAN-Phosphoserine846 relationship: transforms_into CCO:B0065491 ! AHDC1_HUMAN-Phosphoserine1399 relationship: transforms_into CCO:B0065492 ! AHDC1_HUMAN-Phosphoserine1403 relationship: transforms_into CCO:B0065493 ! AHDC1_HUMAN-Phosphoserine1549 [Term] id: CCO:B0063329 name: PTGDS_HUMAN def: "Prostaglandin-H2 D-isomerase precursor" [UniProtKB:P41222] synonym: "Beta-trace protein" EXACT [UniProtKB:P41222] synonym: "Cerebrin-28" EXACT [UniProtKB:P41222] synonym: "EC 5.3.99.2" EXACT [UniProtKB:P41222] synonym: "Glutathione-independent PGD synthetase" EXACT [UniProtKB:P41222] synonym: "Lipocalin-type prostaglandin-D synthase" EXACT [UniProtKB:P41222] synonym: "PGD2 synthase" EXACT [UniProtKB:P41222] synonym: "PGDS" EXACT [UniProtKB:P41222] synonym: "PGDS2" EXACT [UniProtKB:P41222] synonym: "Prostaglandin-D2 synthase" EXACT [UniProtKB:P41222] xref: EMBL:AAA36494.2 xref: EMBL:AAB51074.1 xref: EMBL:AAH05939.1 xref: EMBL:AAH41463.1 xref: EMBL:AAK07679.1 xref: EMBL:AAV38724.1 xref: EMBL:AAV38725.1 xref: EMBL:ABB84464.1 xref: EMBL:CAI12758.1 xref: UniProtKB:P41222 xref: UniProtKB:Q5SQ10 xref: UniProtKB:Q7M4P3 xref: UniProtKB:Q9UC22 xref: UniProtKB:Q9UCC9 xref: UniProtKB:Q9UCD9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022538 ! PTGDS_human relationship: has_function CCO:F0001040 ! prostaglandin-D synthase activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001639 ! retinoid binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000372 ! rough endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: participates_in CCO:I0019079 ! atxn1-ptgds physical interaction relationship: participates_in CCO:I0019102 ! atxn1-ptgds-1 physical interaction [Term] id: CCO:B0063330 name: ZN609_HUMAN def: "Zinc finger protein 609" [UniProtKB:O15014] xref: EMBL:AAI10402.1 xref: EMBL:BAA20755.1 xref: UniProtKB:O15014 xref: UniProtKB:Q0D2I2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022809 ! ZNF609_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019082 ! atxn1-znf609 physical interaction relationship: transforms_into CCO:B0072179 ! ZN609_HUMAN-Phosphoserine576 relationship: transforms_into CCO:B0072180 ! ZN609_HUMAN-Phosphoserine578 relationship: transforms_into CCO:B0072181 ! ZN609_HUMAN-Phosphoserine842 relationship: transforms_into CCO:B0072182 ! ZN609_HUMAN-Phosphoserine846 relationship: transforms_into CCO:B0072183 ! ZN609_HUMAN-Phosphoserine849 [Term] id: CCO:B0063331 name: KLHL8_HUMAN def: "Kelch-like protein 8" [UniProtKB:Q9P2G9] xref: EMBL:AAH41384.1 xref: EMBL:BAA92616.2 xref: UniProtKB:Q9P2G9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022355 ! KLHL8_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019095 ! atxn1-klhl8 physical interaction [Term] id: CCO:B0063332 name: SYNC_HUMAN def: "Asparaginyl-tRNA synthetase, cytoplasmic" [UniProtKB:O43776] synonym: "AsnRS" EXACT [UniProtKB:O43776] synonym: "Asparagine--tRNA ligase" EXACT [UniProtKB:O43776] synonym: "EC 6.1.1.22" EXACT [UniProtKB:O43776] xref: EMBL:AAH01687.1 xref: EMBL:BAA34600.1 xref: EMBL:BAD96555.1 xref: EMBL:CAA04008.1 xref: UniProtKB:O43776 xref: UniProtKB:Q53GU6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022695 ! NARS_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001173 ! aspartate-tRNA ligase activity relationship: has_function CCO:F0001174 ! asparagine-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019100 ! atxn1-nars physical interaction relationship: transforms_into CCO:B0071060 ! SYNC_HUMAN-Phosphoserine61 relationship: transforms_into CCO:B0071061 ! SYNC_HUMAN-Phosphoserine482 [Term] id: CCO:B0063333 name: Q5SQU0_HUMAN def: "SAR1 gene homolog A (S. cerevisiae)" [UniProtKB:Q5SQU0] xref: EMBL:CAI13687.1 xref: UniProtKB:Q5SQU0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0019837 ! SAR1A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: participates_in CCO:I0019103 ! atxn1-sara1 physical interaction [Term] id: CCO:B0063334 name: ERG25_HUMAN def: "C-4 methylsterol oxidase" [UniProtKB:Q15800] synonym: "EC 1.14.13.72" EXACT [UniProtKB:Q15800] synonym: "Methylsterol monooxygenase" EXACT [UniProtKB:Q15800] xref: EMBL:AAB81566.1 xref: EMBL:AAC50587.1 xref: EMBL:AAH10653.1 xref: EMBL:AAI07880.1 xref: UniProtKB:Q15800 xref: UniProtKB:Q32Q24 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022226 ! SC4MOL_human relationship: has_function CCO:F0000052 ! C-4 methylsterol oxidase activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019104 ! atxn1-sc4mol physical interaction [Term] id: CCO:B0063335 name: SFR14_HUMAN def: "Putative splicing factor, arginine/serine-rich 14" [UniProtKB:Q8IX01] synonym: "Arginine/serine-rich-splicing factor 14" EXACT [UniProtKB:Q8IX01] xref: EMBL:AAC06129.1 xref: EMBL:AAH20586.1 xref: EMBL:AAN77117.1 xref: EMBL:BAA20820.2 xref: EMBL:CAI46012.1 xref: EMBL:CAI46117.1 xref: UniProtKB:O15071 xref: UniProtKB:O60369 xref: UniProtKB:Q5JPH7 xref: UniProtKB:Q8IX01 xref: UniProtKB:Q8WUF7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022645 ! SFRS14_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019105 ! atxn1-sfrs14 physical interaction relationship: transforms_into CCO:B0070398 ! SFR14_HUMAN-Phosphothreonine7 relationship: transforms_into CCO:B0070399 ! SFR14_HUMAN-Phosphothreonine275 relationship: transforms_into CCO:B0070400 ! SFR14_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0070401 ! SFR14_HUMAN-Phosphoserine315 relationship: transforms_into CCO:B0070402 ! SFR14_HUMAN-Phosphoserine940 [Term] id: CCO:B0063336 name: SIA7F_HUMAN def: "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" [UniProtKB:Q969X2] synonym: "EC 2.4.99.-" EXACT [UniProtKB:Q969X2] synonym: "GalNAc alpha-2,6-sialyltransferase VI" EXACT [UniProtKB:Q969X2] synonym: "hST6GalNAc VI" EXACT [UniProtKB:Q969X2] synonym: "Sialyltransferase 7F" EXACT [UniProtKB:Q969X2] synonym: "ST6GalNAc VI" EXACT [UniProtKB:Q969X2] xref: EMBL:AAH06564.1 xref: EMBL:AAH07802.1 xref: EMBL:AAH16299.1 xref: EMBL:AAQ89035.1 xref: EMBL:BAA87035.1 xref: EMBL:BAB14715.1 xref: EMBL:CAD45373.1 xref: EMBL:CAG33599.1 xref: EMBL:CAI12609.1 xref: EMBL:CAI12610.1 xref: EMBL:CAI12611.1 xref: EMBL:CAI12612.1 xref: EMBL:EAW87711.1 xref: EMBL:EAW87712.1 xref: EMBL:EAW87714.1 xref: UniProtKB:Q5T9C4 xref: UniProtKB:Q5T9C5 xref: UniProtKB:Q969X2 xref: UniProtKB:Q9H8A2 xref: UniProtKB:Q9ULB8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022653 ! ST6GALNAC6_human relationship: has_function CCO:F0001849 ! sialyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000988 ! integral to Golgi membrane relationship: participates_in CCO:I0019107 ! atxn1-st6galnac6 physical interaction [Term] id: CCO:B0063337 name: Q8NAK8_HUMAN def: "cDNA FLJ35171 fis, clone PLACE6013220, weakly similar to TRICHOHYALIN" [UniProtKB:Q8NAK8] xref: EMBL:BAC03904.1 xref: UniProtKB:Q8NAK8 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019113 ! atxn2-flj35171 physical interaction [Term] id: CCO:B0063338 name: CX045_HUMAN def: "Uncharacterized protein CXorf45" [UniProtKB:Q9H5U8] xref: EMBL:AAI17378.1 xref: EMBL:AAI17380.1 xref: EMBL:BAB15521.1 xref: EMBL:BAD96874.1 xref: EMBL:CAI43016.2 xref: UniProtKB:Q17RC3 xref: UniProtKB:Q5JXY9 xref: UniProtKB:Q9H5U8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022164 ! CXorf45_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019163 ! rere-cxorf45 physical interaction [Term] id: CCO:B0063339 name: EMID2_HUMAN def: "Collagen alpha-1(XXVI) chain precursor" [UniProtKB:Q96A83] synonym: "EMI domain-containing protein 2" EXACT [UniProtKB:Q96A83] synonym: "Emilin and multimerin domain-containing protein 2" EXACT [UniProtKB:Q96A83] synonym: "Protein Emu2" EXACT [UniProtKB:Q96A83] xref: EMBL:CAC94778.1 xref: UniProtKB:Q96A83 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022218 ! EMID2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019172 ! tbp-emid2 physical interaction [Term] id: CCO:B0063340 name: 2DRA_HUMAN def: "HLA class II histocompatibility antigen, DR alpha chain precursor" [UniProtKB:P01903] synonym: "MHC class II antigen DRA" EXACT [UniProtKB:P01903] xref: EMBL:AAA36275.1 xref: EMBL:AAA36301.1 xref: EMBL:AAA36302.1 xref: EMBL:AAA59783.1 xref: EMBL:AAA59785.1 xref: EMBL:AAH32350.1 xref: EMBL:AAH71659.1 xref: EMBL:AAO23887.1 xref: EMBL:CAA23782.1 xref: EMBL:CAA25076.1 xref: EMBL:CAB06609.1 xref: EMBL:CAG33294.1 xref: EMBL:CAI17571.1 xref: EMBL:CAI18266.1 xref: EMBL:CAI18476.1 xref: EMBL:CAM26203.1 xref: EMBL:EAX03630.1 xref: UniProtKB:A2BET4 xref: UniProtKB:P01903 xref: UniProtKB:Q30160 xref: UniProtKB:Q6IAZ1 xref: UniProtKB:Q861I2 xref: UniProtKB:Q9TP70 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0013651 ! HLA-DRA_human relationship: has_function CCO:F0004979 ! MHC class II receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001670 ! MHC class II protein complex relationship: participates_in CCO:I0019183 ! ha-hla_dra-1 physical interaction [Term] id: CCO:B0063341 name: Q8N2T6_HUMAN def: "TRBC1 protein" [UniProtKB:Q8N2T6] xref: EMBL:AAH30533.1 xref: UniProtKB:Q8N2T6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022846 ! TRBC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019183 ! ha-hla_dra-1 physical interaction [Term] id: CCO:B0063342 name: ATPF2_HUMAN def: "ATP synthase mitochondrial F1 complex assembly factor 2 precursor" [UniProtKB:Q8N5M1] synonym: "ATP12 homolog" EXACT [UniProtKB:Q8N5M1] xref: EMBL:AAH04114.1 xref: EMBL:AAH32126.1 xref: EMBL:AAP34466.1 xref: EMBL:BAF82946.1 xref: EMBL:EAW55680.1 xref: UniProtKB:A6NDE5 xref: UniProtKB:A8K2J2 xref: UniProtKB:Q6XYC7 xref: UniProtKB:Q8N5M1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022059 ! ATPAF2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000820 ! nuclear speck relationship: participates_in CCO:I0019190 ! atp12-f1alpha-1 direct interaction [Term] id: CCO:B0063343 name: MUC7_HUMAN def: "Mucin-7 precursor" [UniProtKB:Q8TAX7] synonym: "Apo-MG2" EXACT [UniProtKB:Q8TAX7] synonym: "MUC-7" EXACT [UniProtKB:Q8TAX7] synonym: "Salivary mucin-7" EXACT [UniProtKB:Q8TAX7] xref: EMBL:AAH25688.1 xref: UniProtKB:Q8TAX7 xref: UniProtKB:Q9UCD7 xref: UniProtKB:Q9UCD8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022413 ! MUC7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0019277 ! muc7-lama5 physical interaction relationship: participates_in CCO:I0019278 ! muc7-pfn2 physical interaction [Term] id: CCO:B0063344 name: CSTF2_HUMAN def: "Cleavage stimulation factor 64 kDa subunit" [UniProtKB:P33240] synonym: "CF-1 64 kDa subunit" EXACT [UniProtKB:P33240] synonym: "CSTF 64 kDa subunit" EXACT [UniProtKB:P33240] synonym: "CstF-64" EXACT [UniProtKB:P33240] xref: EMBL:AAA35724.1 xref: EMBL:AAH17712.1 xref: EMBL:AAH33135.1 xref: EMBL:AAP88780.1 xref: EMBL:CAB06072.2 xref: EMBL:CAI42680.1 xref: EMBL:CAI42681.1 xref: UniProtKB:P33240 xref: UniProtKB:Q5H951 xref: UniProtKB:Q6LA74 xref: UniProtKB:Q8N502 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022158 ! CSTF2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019314 ! sub1-cstf2-1 physical interaction relationship: participates_in CCO:I0019535 ! cstf2-chd3 physical interaction relationship: participates_in CCO:I0019701 ! cstf2-htatip physical interaction relationship: participates_in CCO:I0019702 ! cstf2-ikbkap physical interaction relationship: transforms_into CCO:B0065910 ! CSTF2_HUMAN-Phosphoserine154 relationship: transforms_into CCO:B0065911 ! CSTF2_HUMAN-Phosphoserine518 relationship: transforms_into CCO:B0065912 ! CSTF2_HUMAN-Phosphoserine524 [Term] id: CCO:B0063345 name: PEBB_HUMAN def: "Core-binding factor subunit beta" [UniProtKB:Q13951] synonym: "CBF-beta" EXACT [UniProtKB:Q13951] synonym: "PEA2-beta" EXACT [UniProtKB:Q13951] synonym: "PEBP2-beta" EXACT [UniProtKB:Q13951] synonym: "Polyomavirus enhancer-binding protein 2 beta subunit" EXACT [UniProtKB:Q13951] synonym: "SL3-3 enhancer factor 1 subunit beta" EXACT [UniProtKB:Q13951] synonym: "SL3/AKV core-binding factor beta subunit" EXACT [UniProtKB:Q13951] xref: EMBL:AAA02868.1 xref: EMBL:AAH18509.1 xref: EMBL:AAP35508.1 xref: UniProtKB:Q13124 xref: UniProtKB:Q13951 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022499 ! CBFB_human relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0019319 ! cbfb-runx1-1 direct interaction [Term] id: CCO:B0063346 name: CAPR1_HUMAN def: "Caprin-1" [UniProtKB:Q14444] synonym: "Cell cycle associated protein 1" EXACT [UniProtKB:Q14444] synonym: "Cytoplasmic activation- and proliferation-associated protein 1" EXACT [UniProtKB:Q14444] synonym: "GPI-anchored membrane protein 1" EXACT [UniProtKB:Q14444] synonym: "GPI-anchored protein p137" EXACT [UniProtKB:Q14444] synonym: "GPI-p137" EXACT [UniProtKB:Q14444] synonym: "Membrane component chromosome 11 surface marker 1" EXACT [UniProtKB:Q14444] synonym: "p137GPI" EXACT [UniProtKB:Q14444] xref: EMBL:AAH01731.2 xref: EMBL:CAA61751.1 xref: EMBL:CAA88096.1 xref: EMBL:DAA01118.1 xref: EMBL:DAA01121.1 xref: EMBL:EAW68177.1 xref: EMBL:EAW68178.1 xref: UniProtKB:A6NMY7 xref: UniProtKB:Q14444 xref: UniProtKB:Q15074 xref: UniProtKB:Q6IMN4 xref: UniProtKB:Q6IMN7 xref: UniProtKB:Q9BV09 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022087 ! CAPRIN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: transforms_into CCO:B0065818 ! CAPR1_HUMAN-Phosphoserine611 relationship: transforms_into CCO:B0065819 ! CAPR1_HUMAN-Phosphoserine615 [Term] id: CCO:B0063347 name: LMO7_HUMAN def: "LIM domain only protein 7" [UniProtKB:Q8WWI1] synonym: "F-box only protein 20" EXACT [UniProtKB:Q8WWI1] synonym: "LOMP" EXACT [UniProtKB:Q8WWI1] xref: EMBL:AAB86592.1 xref: EMBL:AAC96299.1 xref: EMBL:AAC96300.1 xref: EMBL:AAD33924.1 xref: EMBL:AAF04521.1 xref: EMBL:AAL37480.1 xref: EMBL:BAA74881.2 xref: UniProtKB:O15462 xref: UniProtKB:O95346 xref: UniProtKB:Q8WWI1 xref: UniProtKB:Q9UKC1 xref: UniProtKB:Q9UQM5 xref: UniProtKB:Q9Y6A7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022375 ! LMO7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007836 ! cftr-ebp-2 physical interaction relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0067728 ! LMO7_HUMAN-Phosphoserine246 relationship: transforms_into CCO:B0067729 ! LMO7_HUMAN-Phosphoserine276 relationship: transforms_into CCO:B0067730 ! LMO7_HUMAN-Phosphoserine322 relationship: transforms_into CCO:B0067731 ! LMO7_HUMAN-Phosphotyrosine323 relationship: transforms_into CCO:B0067732 ! LMO7_HUMAN-Phosphoserine342 relationship: transforms_into CCO:B0067733 ! LMO7_HUMAN-Phosphoserine345 relationship: transforms_into CCO:B0067734 ! LMO7_HUMAN-Phosphoserine706 relationship: transforms_into CCO:B0067735 ! LMO7_HUMAN-Phosphoserine709 relationship: transforms_into CCO:B0067736 ! LMO7_HUMAN-Phosphoserine805 relationship: transforms_into CCO:B0067737 ! LMO7_HUMAN-Phosphoserine867 relationship: transforms_into CCO:B0067738 ! LMO7_HUMAN-Phosphoserine873 relationship: transforms_into CCO:B0067739 ! LMO7_HUMAN-Phosphoserine895 relationship: transforms_into CCO:B0067740 ! LMO7_HUMAN-Phosphothreonine913 relationship: transforms_into CCO:B0067741 ! LMO7_HUMAN-Phosphoserine919 relationship: transforms_into CCO:B0067742 ! LMO7_HUMAN-Phosphoserine926 relationship: transforms_into CCO:B0067743 ! LMO7_HUMAN-Phosphothreonine932 relationship: transforms_into CCO:B0067744 ! LMO7_HUMAN-Phosphothreonine949 relationship: transforms_into CCO:B0067745 ! LMO7_HUMAN-Phosphoserine955 relationship: transforms_into CCO:B0067746 ! LMO7_HUMAN-Phosphoserine960 relationship: transforms_into CCO:B0067747 ! LMO7_HUMAN-Phosphoserine988 relationship: transforms_into CCO:B0067748 ! LMO7_HUMAN-Phosphoserine991 relationship: transforms_into CCO:B0067749 ! LMO7_HUMAN-Phosphoserine994 relationship: transforms_into CCO:B0067750 ! LMO7_HUMAN-Phosphoserine995 relationship: transforms_into CCO:B0067751 ! LMO7_HUMAN-Phosphoserine1026 relationship: transforms_into CCO:B0067752 ! LMO7_HUMAN-Phosphoserine1044 relationship: transforms_into CCO:B0067753 ! LMO7_HUMAN-Phosphothreonine1048 relationship: transforms_into CCO:B0067754 ! LMO7_HUMAN-Phosphoserine1423 relationship: transforms_into CCO:B0067755 ! LMO7_HUMAN-Phosphoserine1493 relationship: transforms_into CCO:B0067756 ! LMO7_HUMAN-Phosphoserine1510 relationship: transforms_into CCO:B0067757 ! LMO7_HUMAN-Phosphoserine1516 relationship: transforms_into CCO:B0067758 ! LMO7_HUMAN-Phosphoserine1563 relationship: transforms_into CCO:B0067759 ! LMO7_HUMAN-Phosphoserine1586 relationship: transforms_into CCO:B0067760 ! LMO7_HUMAN-Phosphoserine1593 relationship: transforms_into CCO:B0067761 ! LMO7_HUMAN-Phosphoserine1595 relationship: transforms_into CCO:B0067762 ! LMO7_HUMAN-Phosphoserine1597 relationship: transforms_into CCO:B0067763 ! LMO7_HUMAN-Phosphoserine1601 relationship: transforms_into CCO:B0067764 ! LMO7_HUMAN-Phosphotyrosine1672 [Term] id: CCO:B0063348 name: F10C1_HUMAN def: "Protein FRA10AC1" [UniProtKB:Q70Z53] xref: EMBL:AAH18007.1 xref: EMBL:AAK55529.1 xref: EMBL:BAC03556.1 xref: EMBL:CAD24470.1 xref: EMBL:CAD24471.1 xref: EMBL:CAD24472.1 xref: EMBL:CAD24473.1 xref: EMBL:CAD24474.1 xref: EMBL:CAH73836.1 xref: UniProtKB:Q70Z49 xref: UniProtKB:Q70Z50 xref: UniProtKB:Q70Z51 xref: UniProtKB:Q70Z52 xref: UniProtKB:Q70Z53 xref: UniProtKB:Q8N293 xref: UniProtKB:Q8WVH5 xref: UniProtKB:Q96JQ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022238 ! FRA10AC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019403 ! c10orf4-map3k12-1 physical interaction relationship: participates_in CCO:I0019929 ! fra10ac1-eef1d physical interaction relationship: participates_in CCO:I0020517 ! fra10ac1-map3k12 physical interaction relationship: transforms_into CCO:B0066042 ! F10C1_HUMAN-Phosphoserine12 relationship: transforms_into CCO:B0066043 ! F10C1_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0066044 ! F10C1_HUMAN-Phosphoserine252 relationship: transforms_into CCO:B0066045 ! F10C1_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0066046 ! F10C1_HUMAN-Phosphoserine285 [Term] id: CCO:B0063349 name: PTN4_HUMAN def: "Tyrosine-protein phosphatase non-receptor type 4" [UniProtKB:P29074] synonym: "EC 3.1.3.48" EXACT [UniProtKB:P29074] synonym: "MEG" EXACT [UniProtKB:P29074] synonym: "Protein-tyrosine phosphatase MEG1" EXACT [UniProtKB:P29074] synonym: "PTPase-MEG1" EXACT [UniProtKB:P29074] xref: EMBL:AAA36530.1 xref: EMBL:AAH10674.1 xref: UniProtKB:P29074 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022542 ! PTPN4_human relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001091 ! non-membrane spanning protein tyrosine phosphatase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: participates_in CCO:I0019406 ! ptpn4-htatip-1 physical interaction relationship: participates_in CCO:I0019805 ! ptpn4-htatip physical interaction relationship: participates_in CCO:I0019921 ! atrx-ptpn4 physical interaction [Term] id: CCO:B0063350 name: TRI11_HUMAN def: "Tripartite motif-containing protein 11" [UniProtKB:Q96F44] synonym: "EC 6.3.2.-" EXACT [UniProtKB:Q96F44] synonym: "Protein BIA1" EXACT [UniProtKB:Q96F44] synonym: "RING finger protein 92" EXACT [UniProtKB:Q96F44] xref: EMBL:AAG53498.1 xref: EMBL:AAH11629.1 xref: EMBL:AAH69227.1 xref: EMBL:AAM63957.1 xref: EMBL:BAC11254.1 xref: EMBL:CAH71671.1 xref: EMBL:CAH71672.1 xref: UniProtKB:A6NKE2 xref: UniProtKB:Q5VSU1 xref: UniProtKB:Q8NCA6 xref: UniProtKB:Q96F44 xref: UniProtKB:Q9C022 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022732 ! TRIM11_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0019441 ! pax6-trim11-1 physical interaction relationship: participates_in CCO:I0019511 ! pax6-trim11-2 physical interaction [Term] id: CCO:B0063351 name: TRPC7_HUMAN def: "Short transient receptor potential channel 7" [UniProtKB:Q9HCX4] synonym: "TRP7 protein" EXACT [UniProtKB:Q9HCX4] synonym: "TrpC7" EXACT [UniProtKB:Q9HCX4] xref: EMBL:CAC03489.1 xref: UniProtKB:Q9HCX4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022742 ! TRPC7_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019453 ! mx1-trpc7-7 physical interaction [Term] id: CCO:B0063352 name: H2B1H_HUMAN def: "Histone H2B type 1-H" [UniProtKB:Q93079] synonym: "H2B.j" EXACT [UniProtKB:Q93079] synonym: "H2B/j" EXACT [UniProtKB:Q93079] xref: EMBL:AAH96116.1 xref: EMBL:AAH96117.1 xref: EMBL:AAH96118.1 xref: EMBL:AAH96119.1 xref: EMBL:AAN06691.1 xref: EMBL:CAB02543.1 xref: EMBL:CAB39185.1 xref: UniProtKB:Q4VB74 xref: UniProtKB:Q93079 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022298 ! HIST1H2BH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0066710 ! H2B1H_HUMAN-N6-acetyllysine6 relationship: transforms_into CCO:B0066711 ! H2B1H_HUMAN-N6-acetyllysine12 relationship: transforms_into CCO:B0066712 ! H2B1H_HUMAN-N6-acetyllysine13 relationship: transforms_into CCO:B0066713 ! H2B1H_HUMAN-Phosphoserine15 relationship: transforms_into CCO:B0066714 ! H2B1H_HUMAN-N6-acetyllysine16 relationship: transforms_into CCO:B0066715 ! H2B1H_HUMAN-N6-acetyllysine17 relationship: transforms_into CCO:B0066716 ! H2B1H_HUMAN-N6-acetyllysine21 relationship: transforms_into CCO:B0066717 ! H2B1H_HUMAN-N6-acetyllysine24 relationship: transforms_into CCO:B0066718 ! H2B1H_HUMAN-N6-methyllysine47 relationship: transforms_into CCO:B0066719 ! H2B1H_HUMAN-N6,N6-dimethyllysine58 relationship: transforms_into CCO:B0066720 ! H2B1H_HUMAN-N6-acetyllysine109 relationship: transforms_into CCO:B0066721 ! H2B1H_HUMAN-N6-methyllysine109 [Term] id: CCO:B0063353 name: RS26_HUMAN def: "40S ribosomal protein S26" [UniProtKB:P62854] xref: EMBL:AAC26987.1 xref: EMBL:AAH02604.1 xref: EMBL:AAH15832.1 xref: EMBL:AAH70220.1 xref: EMBL:AAI05277.1 xref: EMBL:AAI05799.1 xref: EMBL:CAA49345.1 xref: EMBL:CAA54808.1 xref: EMBL:CAA55818.1 xref: UniProtKB:P02383 xref: UniProtKB:P62854 xref: UniProtKB:P70394 xref: UniProtKB:Q06722 xref: UniProtKB:Q3MHD8 xref: UniProtKB:Q6IRY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022612 ! RPS26_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0070201 ! RS26_HUMAN-Phosphothreonine96 [Term] id: CCO:B0063354 name: AP2A1_HUMAN def: "AP-2 complex subunit alpha-1" [UniProtKB:O95782] synonym: "100 kDa coated vesicle protein A" EXACT [UniProtKB:O95782] synonym: "Adapter-related protein complex 2 alpha-1 subunit" EXACT [UniProtKB:O95782] synonym: "Adaptor protein complex AP-2 subunit alpha-1" EXACT [UniProtKB:O95782] synonym: "Alpha-adaptin A" EXACT [UniProtKB:O95782] synonym: "Alpha1-adaptin" EXACT [UniProtKB:O95782] synonym: "Clathrin assembly protein complex 2 alpha-A large chain" EXACT [UniProtKB:O95782] synonym: "Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit" EXACT [UniProtKB:O95782] xref: EMBL:AAD15564.1 xref: EMBL:AAH14214.1 xref: EMBL:AAL11039.1 xref: EMBL:AAL11040.1 xref: EMBL:CAB66859.1 xref: UniProtKB:O95782 xref: UniProtKB:Q96CI7 xref: UniProtKB:Q96PP6 xref: UniProtKB:Q96PP7 xref: UniProtKB:Q9H070 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022038 ! AP2A1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0020652 ! rit1-ap2a1 physical interaction relationship: transforms_into CCO:B0065660 ! AP2A1_HUMAN-Phosphothreonine650 relationship: transforms_into CCO:B0065661 ! AP2A1_HUMAN-Phosphoserine652 relationship: transforms_into CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: transforms_into CCO:B0065663 ! AP2A1_HUMAN-Phosphoserine655 [Term] id: CCO:B0063355 name: HNRH2_HUMAN def: "Heterogeneous nuclear ribonucleoprotein H2" [UniProtKB:P55795] synonym: "FTP-3" EXACT [UniProtKB:P55795] synonym: "Heterogeneous nuclear ribonucleoprotein H'" EXACT [UniProtKB:P55795] synonym: "hnRNP H'" EXACT [UniProtKB:P55795] synonym: "hnRNP H2" EXACT [UniProtKB:P55795] xref: EMBL:AAB64202.1 xref: EMBL:CAB55879.2 xref: UniProtKB:P55795 xref: UniProtKB:Q9HHA7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022309 ! HNRNPH2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0066855 ! HNRH2_HUMAN-Phosphoserine104 relationship: transforms_into CCO:B0066856 ! HNRH2_HUMAN-Phosphothreonine107 relationship: transforms_into CCO:B0066857 ! HNRH2_HUMAN-Asymmetric dimethylarginine217 relationship: transforms_into CCO:B0066858 ! HNRH2_HUMAN-Phosphoserine310 [Term] id: CCO:B0063356 name: RL27A_HUMAN def: "60S ribosomal protein L27a" [UniProtKB:P46776] xref: EMBL:AAA85656.1 xref: EMBL:AAH05326.1 xref: EMBL:AAH20169.1 xref: EMBL:BAA25837.1 xref: EMBL:BAA77361.1 xref: UniProtKB:P46776 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022574 ! RPL27A_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0063357 name: UGDH_HUMAN def: "UDP-glucose 6-dehydrogenase" [UniProtKB:O60701] synonym: "EC 1.1.1.22" EXACT [UniProtKB:O60701] synonym: "UDP-Glc dehydrogenase" EXACT [UniProtKB:O60701] synonym: "UDP-GlcDH" EXACT [UniProtKB:O60701] synonym: "UDPGDH" EXACT [UniProtKB:O60701] xref: EMBL:AAC05135.1 xref: EMBL:AAC36095.1 xref: EMBL:AAH22781.1 xref: EMBL:CAA07609.1 xref: EMBL:CAB75891.1 xref: UniProtKB:O60589 xref: UniProtKB:O60701 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022765 ! UGDH_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0071714 ! UGDH_HUMAN-Phosphotyrosine473 [Term] id: CCO:B0063358 name: ADT1_HUMAN def: "ADP/ATP translocase 1" [UniProtKB:P12235] synonym: "Adenine nucleotide translocator 1" EXACT [UniProtKB:P12235] synonym: "ADP,ATP carrier protein 1" EXACT [UniProtKB:P12235] synonym: "ADP,ATP carrier protein, heart/skeletal muscle isoform T1" EXACT [UniProtKB:P12235] synonym: "ANT 1" EXACT [UniProtKB:P12235] synonym: "Solute carrier family 25 member 4" EXACT [UniProtKB:P12235] xref: EMBL:AAA36751.1 xref: EMBL:AAA51736.1 xref: EMBL:AAA61223.1 xref: EMBL:AAH08664.1 xref: EMBL:AAH61589.1 xref: EMBL:AAH63643.1 xref: UniProtKB:P12235 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022026 ! SLC25A4_human relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001626 ! ATP:ADP antiporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002678 ! adenine transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0065445 ! ADT1_HUMAN-N-acetylglycine2 relationship: transforms_into CCO:B0065446 ! ADT1_HUMAN-Phosphothreonine126 relationship: transforms_into CCO:B0065447 ! ADT1_HUMAN-Phosphoserine127 relationship: transforms_into CCO:B0065448 ! ADT1_HUMAN-Phosphotyrosine191 relationship: transforms_into CCO:B0065449 ! ADT1_HUMAN-Phosphotyrosine195 [Term] id: CCO:B0063359 name: DLDH_HUMAN def: "Dihydrolipoyl dehydrogenase, mitochondrial precursor" [UniProtKB:P09622] synonym: "Dihydrolipoamide dehydrogenase" EXACT [UniProtKB:P09622] synonym: "EC 1.8.1.4" EXACT [UniProtKB:P09622] synonym: "Glycine cleavage system L protein" EXACT [UniProtKB:P09622] xref: EMBL:AAA35759.1 xref: EMBL:AAA35764.1 xref: EMBL:AAA59527.1 xref: EMBL:AAB01381.1 xref: EMBL:AAH18648.1 xref: EMBL:AAH18696.1 xref: EMBL:BAD92940.1 xref: EMBL:EAL24389.1 xref: UniProtKB:P09622 xref: UniProtKB:Q14131 xref: UniProtKB:Q14167 xref: UniProtKB:Q59EV8 xref: UniProtKB:Q8WTS4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022190 ! DLD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0065953 ! DLDH_HUMAN-N6-acetyllysine127 [Term] id: CCO:B0063360 name: RL23A_HUMAN def: "60S ribosomal protein L23a" [UniProtKB:P62750] xref: EMBL:AAA03341.1 xref: EMBL:AAA35681.1 xref: EMBL:AAB03210.1 xref: EMBL:AAB17510.1 xref: EMBL:AAC51934.1 xref: EMBL:AAH14459.1 xref: EMBL:AAH58041.1 xref: UniProtKB:P29316 xref: UniProtKB:P39024 xref: UniProtKB:P62750 xref: UniProtKB:Q92774 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022572 ! RPL23A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0070078 ! RL23A_HUMAN-Phosphoserine43 [Term] id: CCO:B0063361 name: GLYM_HUMAN def: "Serine hydroxymethyltransferase, mitochondrial precursor" [UniProtKB:P34897] synonym: "EC 2.1.2.1" EXACT [UniProtKB:P34897] synonym: "Glycine hydroxymethyltransferase" EXACT [UniProtKB:P34897] synonym: "Serine methylase" EXACT [UniProtKB:P34897] synonym: "SHMT" EXACT [UniProtKB:P34897] xref: EMBL:AAA63258.1 xref: EMBL:AAA64572.1 xref: EMBL:AAH11911.1 xref: EMBL:AAH13677.1 xref: EMBL:AAH44211.1 xref: EMBL:AAP35512.1 xref: EMBL:CAA72999.1 xref: UniProtKB:O00740 xref: UniProtKB:P34897 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022279 ! SHMT2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000791 ! glycine hydroxymethyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0063362 name: TPM2_HUMAN def: "Tropomyosin beta chain" [UniProtKB:P07951] synonym: "Beta-tropomyosin" EXACT [UniProtKB:P07951] synonym: "Tropomyosin-2" EXACT [UniProtKB:P07951] xref: EMBL:AAA36773.1 xref: EMBL:AAA51842.1 xref: EMBL:AAA61229.1 xref: EMBL:AAA61230.1 xref: EMBL:AAB59509.1 xref: EMBL:AAF17621.1 xref: EMBL:AAH11776.1 xref: EMBL:BAD96978.1 xref: EMBL:CAA29971.1 xref: EMBL:CAI10974.1 xref: EMBL:CAI10977.1 xref: EMBL:EAW58354.1 xref: UniProtKB:A6NM85 xref: UniProtKB:P06468 xref: UniProtKB:P07951 xref: UniProtKB:Q13894 xref: UniProtKB:Q53FM4 xref: UniProtKB:Q5TCU4 xref: UniProtKB:Q5TCU7 xref: UniProtKB:Q9UH67 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022729 ! TPM2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0071478 ! TPM2_HUMAN-N-acetylmethionine1 relationship: transforms_into CCO:B0071479 ! TPM2_HUMAN-Phosphothreonine252 relationship: transforms_into CCO:B0071480 ! TPM2_HUMAN-Phosphoserine283 [Term] id: CCO:B0063363 name: SERPH_HUMAN def: "Serpin H1 precursor" [UniProtKB:P50454] synonym: "47 kDa heat shock protein" EXACT [UniProtKB:P50454] synonym: "Arsenic-transactivated protein 3" EXACT [UniProtKB:P50454] synonym: "AsTP3" EXACT [UniProtKB:P50454] synonym: "Cell proliferation-inducing gene 14 protein" EXACT [UniProtKB:P50454] synonym: "Collagen-binding protein" EXACT [UniProtKB:P50454] synonym: "Colligin" EXACT [UniProtKB:P50454] synonym: "Rheumatoid arthritis-related antigen RA-A47" EXACT [UniProtKB:P50454] xref: EMBL:AAH14623.1 xref: EMBL:AAH36298.2 xref: EMBL:AAH70087.1 xref: EMBL:AAP35758.1 xref: EMBL:AAP93914.1 xref: EMBL:AAU95378.1 xref: EMBL:BAA11829.1 xref: EMBL:BAA96788.1 xref: EMBL:BAA96789.1 xref: EMBL:CAA43795.1 xref: UniProtKB:P29043 xref: UniProtKB:P50454 xref: UniProtKB:Q5XPB4 xref: UniProtKB:Q6NSJ6 xref: UniProtKB:Q8IY96 xref: UniProtKB:Q9NP88 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022643 ! SERPINH1_human relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001649 ! collagen binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0063364 name: ARPC4_HUMAN def: "Actin-related protein 2/3 complex subunit 4" [UniProtKB:P59998] synonym: "Arp2/3 complex 20 kDa subunit" EXACT [UniProtKB:P59998] synonym: "p20-ARC" EXACT [UniProtKB:P59998] xref: EMBL:AAB64192.1 xref: EMBL:AAB71548.1 xref: EMBL:AAH12596.3 xref: UniProtKB:O15509 xref: UniProtKB:P59998 xref: UniProtKB:Q6P0W5 xref: UniProtKB:Q96QJ3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022050 ! ARPC4_human relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000443 ! Arp2/3 protein complex relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0019526 ! arpc5l-arpc4 physical interaction relationship: participates_in CCO:I0020477 ! th1l-arpc4 physical interaction relationship: transforms_into CCO:B0065752 ! ARPC4_HUMAN-N-acetylthreonine2 [Term] id: CCO:B0063365 name: ABLM3_HUMAN def: "Actin-binding LIM protein 3" [UniProtKB:O94929] synonym: "abLIM-3" EXACT [UniProtKB:O94929] synonym: "Actin-binding LIM protein family member 3" EXACT [UniProtKB:O94929] xref: EMBL:AAH01665.1 xref: EMBL:ABD83327.1 xref: EMBL:BAA74866.2 xref: EMBL:BAD38663.1 xref: EMBL:BAF82425.1 xref: EMBL:CAH56270.1 xref: UniProtKB:A8K121 xref: UniProtKB:O94929 xref: UniProtKB:Q19VH3 xref: UniProtKB:Q658S1 xref: UniProtKB:Q68CI5 xref: UniProtKB:Q9BV32 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022022 ! ABLIM3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0065301 ! ABLM3_HUMAN-Phosphoserine277 relationship: transforms_into CCO:B0065302 ! ABLM3_HUMAN-Phosphoserine280 relationship: transforms_into CCO:B0065303 ! ABLM3_HUMAN-Phosphoserine282 relationship: transforms_into CCO:B0065304 ! ABLM3_HUMAN-Phosphoserine372 relationship: transforms_into CCO:B0065305 ! ABLM3_HUMAN-Phosphoserine373 relationship: transforms_into CCO:B0065306 ! ABLM3_HUMAN-Phosphoserine388 relationship: transforms_into CCO:B0065307 ! ABLM3_HUMAN-Phosphoserine394 relationship: transforms_into CCO:B0065308 ! ABLM3_HUMAN-Phosphoserine503 relationship: transforms_into CCO:B0065309 ! ABLM3_HUMAN-Phosphoserine504 [Term] id: CCO:B0063366 name: GMFB_HUMAN def: "Glia maturation factor beta" [UniProtKB:P60983] synonym: "GMF-beta" EXACT [UniProtKB:P60983] xref: EMBL:AAA58614.1 xref: EMBL:BAA19232.1 xref: EMBL:CAG46910.1 xref: UniProtKB:P17774 xref: UniProtKB:P60983 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022280 ! GMFB_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0066474 ! GMFB_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0066475 ! GMFB_HUMAN-Phosphotyrosine84 [Term] id: CCO:B0063367 name: RL26_HUMAN def: "60S ribosomal protein L26" [UniProtKB:P61254] xref: EMBL:AAA60279.1 xref: EMBL:AAH71664.1 xref: EMBL:BAB79467.1 xref: EMBL:CAA49189.1 xref: UniProtKB:P61254 xref: UniProtKB:Q02877 xref: UniProtKB:Q6IPY2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022573 ! RPL26_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0070079 ! RL26_HUMAN-Phosphothreonine139 [Term] id: CCO:B0063368 name: RS28_HUMAN def: "40S ribosomal protein S28" [UniProtKB:P62857] xref: EMBL:AAB07066.1 xref: EMBL:AAC15855.1 xref: EMBL:AAH00354.1 xref: EMBL:AAH21239.1 xref: EMBL:AAH70217.1 xref: EMBL:AAH70218.1 xref: EMBL:BAA28594.1 xref: EMBL:BAB79484.1 xref: EMBL:CAG33336.1 xref: UniProtKB:P25112 xref: UniProtKB:P62857 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022613 ! RPS28_human relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0070202 ! RS28_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0063369 name: TPM1_HUMAN def: "Tropomyosin alpha-1 chain" [UniProtKB:P09493] synonym: "Alpha-tropomyosin" EXACT [UniProtKB:P09493] synonym: "Tropomyosin-1" EXACT [UniProtKB:P09493] xref: EMBL:AAA36771.1 xref: EMBL:AAA61225.1 xref: EMBL:AAA61226.1 xref: EMBL:AAA61227.1 xref: EMBL:AAH07433.1 xref: EMBL:AAH50473.1 xref: EMBL:CAA30930.1 xref: UniProtKB:P09493 xref: UniProtKB:P09494 xref: UniProtKB:P10469 xref: UniProtKB:Q86W64 xref: UniProtKB:Q96IK2 xref: UniProtKB:Q9UCY9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022728 ! TPM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0071477 ! TPM1_HUMAN-N-acetylmethionine1 [Term] id: CCO:B0063370 name: SRC8_HUMAN def: "Src substrate cortactin" [UniProtKB:Q14247] synonym: "Amplaxin" EXACT [UniProtKB:Q14247] synonym: "Oncogene EMS1" EXACT [UniProtKB:Q14247] xref: EMBL:AAA58455.1 xref: UniProtKB:Q14247 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022677 ! CTTN_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: transforms_into CCO:B0070884 ! SRC8_HUMAN-Phosphoserine113 relationship: transforms_into CCO:B0070885 ! SRC8_HUMAN-Phosphoserine117 relationship: transforms_into CCO:B0070886 ! SRC8_HUMAN-Phosphotyrosine141 relationship: transforms_into CCO:B0070887 ! SRC8_HUMAN-Phosphotyrosine215 relationship: transforms_into CCO:B0070888 ! SRC8_HUMAN-Phosphotyrosine334 relationship: transforms_into CCO:B0070889 ! SRC8_HUMAN-Phosphothreonine399 relationship: transforms_into CCO:B0070890 ! SRC8_HUMAN-Phosphothreonine401 relationship: transforms_into CCO:B0070891 ! SRC8_HUMAN-Phosphoserine405 relationship: transforms_into CCO:B0070892 ! SRC8_HUMAN-Phosphothreonine411 relationship: transforms_into CCO:B0070893 ! SRC8_HUMAN-Phosphoserine417 relationship: transforms_into CCO:B0070894 ! SRC8_HUMAN-Phosphoserine418 relationship: transforms_into CCO:B0070895 ! SRC8_HUMAN-Phosphotyrosine421 relationship: transforms_into CCO:B0070896 ! SRC8_HUMAN-Phosphotyrosine446 relationship: transforms_into CCO:B0070897 ! SRC8_HUMAN-Phosphotyrosine453 [Term] id: CCO:B0063371 name: CBR1_HUMAN def: "Carbonyl reductase [NADPH] 1" [UniProtKB:P16152] synonym: "15-hydroxyprostaglandin dehydrogenase [NADP+]" EXACT [UniProtKB:P16152] synonym: "EC 1.1.1.184" EXACT [UniProtKB:P16152] synonym: "EC 1.1.1.189" EXACT [UniProtKB:P16152] synonym: "EC 1.1.1.197" EXACT [UniProtKB:P16152] synonym: "NADPH-dependent carbonyl reductase 1" EXACT [UniProtKB:P16152] synonym: "Prostaglandin 9-ketoreductase" EXACT [UniProtKB:P16152] synonym: "Prostaglandin-E(2) 9-reductase" EXACT [UniProtKB:P16152] xref: EMBL:AAA17881.1 xref: EMBL:AAA52070.1 xref: EMBL:AAH02511.1 xref: EMBL:AAH15640.1 xref: EMBL:AAV38646.1 xref: EMBL:ABK97430.1 xref: EMBL:BAA33498.1 xref: EMBL:BAA89424.1 xref: EMBL:BAA95508.1 xref: EMBL:BAE45940.1 xref: EMBL:CAG46509.1 xref: UniProtKB:P16152 xref: UniProtKB:Q3LHW8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022092 ! CBR1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction relationship: participates_in CCO:I0020526 ! cbr1-ercc8 physical interaction relationship: transforms_into CCO:B0065831 ! CBR1_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0065832 ! CBR1_HUMAN-Phosphotyrosine194 relationship: transforms_into CCO:B0065833 ! CBR1_HUMAN-N6-1-carboxyethyl lysine239 [Term] id: CCO:B0063372 name: CT160_HUMAN def: "Uncharacterized protein C20orf160" [UniProtKB:Q9NUG4] xref: EMBL:AAH30254.1 xref: EMBL:AAH32455.1 xref: EMBL:BAB71363.1 xref: EMBL:CAI42581.1 xref: UniProtKB:Q5JYR9 xref: UniProtKB:Q8N5F1 xref: UniProtKB:Q8N6G8 xref: UniProtKB:Q96MD5 xref: UniProtKB:Q9NUG4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022159 ! C20orf160_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0007948 ! egfr-shc1-1 physical interaction [Term] id: CCO:B0063373 name: LDLR_HUMAN def: "Low-density lipoprotein receptor precursor" [UniProtKB:P01130] synonym: "LDL receptor" EXACT [UniProtKB:P01130] xref: EMBL:AAA56833.1 xref: EMBL:AAH14514.1 xref: EMBL:AAM56036.1 xref: EMBL:AAP36025.1 xref: EMBL:AAP72971.1 xref: UniProtKB:P01130 xref: UniProtKB:Q53ZD9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022364 ! LDLR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019518 ! ldlr-hsp90b1 physical interaction relationship: transforms_into CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 [Term] id: CCO:B0063374 name: TTHY_HUMAN def: "Transthyretin precursor" [UniProtKB:P02766] synonym: "ATTR" EXACT [UniProtKB:P02766] synonym: "Prealbumin" EXACT [UniProtKB:P02766] synonym: "TBPA" EXACT [UniProtKB:P02766] synonym: "TTR" EXACT [UniProtKB:P02766] xref: EMBL:AAA36784.1 xref: EMBL:AAA60011.1 xref: EMBL:AAA60012.1 xref: EMBL:AAA60013.1 xref: EMBL:AAA60018.1 xref: EMBL:AAA61181.1 xref: EMBL:AAA73473.1 xref: EMBL:AAA98771.1 xref: EMBL:AAD14098.1 xref: EMBL:AAD14937.2 xref: EMBL:AAH05310.1 xref: EMBL:AAH20791.1 xref: EMBL:AAP35853.1 xref: EMBL:BAA00059.1 xref: EMBL:CAA42087.1 xref: EMBL:CAG33189.1 xref: UniProtKB:P02766 xref: UniProtKB:Q6IB96 xref: UniProtKB:Q9UBZ6 xref: UniProtKB:Q9UCM9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022748 ! TTR_human relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0002782 ! thyroid hormone transmembrane transporter activity relationship: has_function CCO:F0003468 ! retinal binding relationship: has_function CCO:F0004190 ! retinol binding relationship: has_function CCO:F0005682 ! hormone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: participates_in CCO:I0019581 ! ddr1-ttr physical interaction relationship: participates_in CCO:I0019637 ! ttr-ikbkap physical interaction relationship: participates_in CCO:I0019869 ! ttr-chd3 physical interaction relationship: participates_in CCO:I0019870 ! ttr-setdb1 physical interaction relationship: transforms_into CCO:B0071626 ! TTHY_HUMAN-4-carboxyglutamate62 [Term] id: CCO:B0063375 name: ALDH2_HUMAN def: "Aldehyde dehydrogenase, mitochondrial precursor" [UniProtKB:P05091] synonym: "ALDH class 2" EXACT [UniProtKB:P05091] synonym: "ALDH-E2" EXACT [UniProtKB:P05091] synonym: "ALDHI" EXACT [UniProtKB:P05091] synonym: "EC 1.2.1.3" EXACT [UniProtKB:P05091] xref: EMBL:AAA51693.1 xref: EMBL:AAA51694.1 xref: EMBL:AAA62825.1 xref: EMBL:AAB59500.1 xref: EMBL:AAH02967.1 xref: EMBL:AAH71839.1 xref: EMBL:AAT41621.1 xref: EMBL:CAA28990.1 xref: EMBL:CAA68290.1 xref: EMBL:CAG33272.1 xref: UniProtKB:P05091 xref: UniProtKB:Q03639 xref: UniProtKB:Q6IB13 xref: UniProtKB:Q6IV71 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022032 ! ALDH2_human relationship: has_function CCO:F0000507 ! aldehyde dehydrogenase (NAD) activity relationship: has_function CCO:F0000508 ! aldehyde dehydrogenase [NAD(P)+] activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0019596 ! itgb3bp-aldh2 physical interaction relationship: transforms_into CCO:B0065591 ! ALDH2_HUMAN-N6-acetyllysine368 [Term] id: CCO:B0063376 name: RSRC1_HUMAN def: "Arginine/serine-rich coiled-coil protein 1" [UniProtKB:Q96IZ7] xref: EMBL:AAF64267.1 xref: EMBL:AAH06982.1 xref: EMBL:AAH10357.1 xref: UniProtKB:Q96IZ7 xref: UniProtKB:Q96QK2 xref: UniProtKB:Q9NZE5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022617 ! RSRC1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019602 ! rsrc1-gdf9 physical interaction [Term] id: CCO:B0063377 name: ECH1_HUMAN def: "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor" [UniProtKB:Q13011] synonym: "EC 5.3.3.-" EXACT [UniProtKB:Q13011] xref: EMBL:AAB86485.1 xref: EMBL:AAC50222.1 xref: EMBL:AAH11792.1 xref: EMBL:AAH17408.1 xref: UniProtKB:Q13011 xref: UniProtKB:Q8WVX0 xref: UniProtKB:Q96EZ9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022208 ! ECH1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019629 ! timp1-ech1 physical interaction relationship: participates_in CCO:I0020165 ! serpinb9-ech1 physical interaction relationship: transforms_into CCO:B0065974 ! ECH1_HUMAN-Phosphoserine28 relationship: transforms_into CCO:B0065975 ! ECH1_HUMAN-Phosphoserine30 [Term] id: CCO:B0063378 name: CN139_HUMAN def: "Uncharacterized protein C14orf139" [UniProtKB:Q9H761] xref: EMBL:AAH08299.1 xref: EMBL:BAB15037.1 xref: EMBL:CAG33618.1 xref: UniProtKB:Q6IA18 xref: UniProtKB:Q9H761 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022139 ! C14orf139_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019672 ! c14orf139-sqstm1 physical interaction [Term] id: CCO:B0063379 name: F134A_HUMAN def: "Protein FAM134A" [UniProtKB:Q8NC44] xref: EMBL:AAH64950.1 xref: EMBL:BAC11332.1 xref: EMBL:CAB66692.2 xref: UniProtKB:Q6P1P5 xref: UniProtKB:Q8NC44 xref: UniProtKB:Q9H0K7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022240 ! FAM134A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019678 ! c2orf17-chd3 physical interaction relationship: transforms_into CCO:B0066054 ! F134A_HUMAN-Phosphothreonine279 relationship: transforms_into CCO:B0066055 ! F134A_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0066056 ! F134A_HUMAN-Phosphoserine283 relationship: transforms_into CCO:B0066057 ! F134A_HUMAN-Phosphothreonine306 relationship: transforms_into CCO:B0066058 ! F134A_HUMAN-Phosphoserine308 relationship: transforms_into CCO:B0066059 ! F134A_HUMAN-Phosphoserine311 relationship: transforms_into CCO:B0066060 ! F134A_HUMAN-Phosphoserine385 [Term] id: CCO:B0063380 name: PDIP2_HUMAN def: "Polymerase delta-interacting protein 2" [UniProtKB:Q9Y2S7] synonym: "38 kDa DNA polymerase delta interaction protein" EXACT [UniProtKB:Q9Y2S7] synonym: "p38" EXACT [UniProtKB:Q9Y2S7] xref: EMBL:AAD26998.1 xref: EMBL:AAH00655.1 xref: EMBL:AAH09265.1 xref: EMBL:AAK92018.1 xref: UniProtKB:Q96JE4 xref: UniProtKB:Q9Y2S7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022497 ! POLDIP2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0019696 ! cpe-poldip2 physical interaction relationship: participates_in CCO:I0019910 ! ascc2-poldip2 physical interaction [Term] id: CCO:B0063381 name: EPN1_HUMAN def: "Epsin-1" [UniProtKB:Q9Y6I3] synonym: "EH domain-binding mitotic phosphoprotein" EXACT [UniProtKB:Q9Y6I3] synonym: "EPS-15-interacting protein 1" EXACT [UniProtKB:Q9Y6I3] xref: EMBL:AAD38326.1 xref: EMBL:AAH44651.1 xref: EMBL:BAB14041.1 xref: UniProtKB:Q86ST3 xref: UniProtKB:Q9HA18 xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022222 ! EPN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019713 ! epn1-med31 physical interaction relationship: transforms_into CCO:B0066009 ! EPN1_HUMAN-Phosphoserine357 relationship: transforms_into CCO:B0066010 ! EPN1_HUMAN-Phosphoserine395 relationship: transforms_into CCO:B0066011 ! EPN1_HUMAN-Phosphoserine410 relationship: transforms_into CCO:B0066012 ! EPN1_HUMAN-Phosphoserine429 relationship: transforms_into CCO:B0066013 ! EPN1_HUMAN-Phosphothreonine435 relationship: transforms_into CCO:B0066014 ! EPN1_HUMAN-Phosphothreonine439 relationship: transforms_into CCO:B0066015 ! EPN1_HUMAN-Phosphothreonine469 [Term] id: CCO:B0063382 name: HNRPR_HUMAN def: "Heterogeneous nuclear ribonucleoprotein R" [UniProtKB:O43390] synonym: "hnRNP R" EXACT [UniProtKB:O43390] xref: EMBL:AAC39540.1 xref: EMBL:CAI19026.1 xref: UniProtKB:O43390 xref: UniProtKB:Q5TEH1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022311 ! HNRNPR_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: participates_in CCO:I0019736 ! hnrpr-hrmt1l2 physical interaction [Term] id: CCO:B0063383 name: LYAR_HUMAN def: "Cell growth-regulating nucleolar protein" [UniProtKB:Q9NX58] xref: EMBL:AAF42870.1 xref: EMBL:AAH15796.1 xref: EMBL:BAA91162.1 xref: EMBL:CAB66684.1 xref: EMBL:CAG38579.1 xref: UniProtKB:Q6FI78 xref: UniProtKB:Q9NX58 xref: UniProtKB:Q9NYS1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022381 ! LYAR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019759 ! lyar-zhx1 physical interaction relationship: transforms_into CCO:B0067797 ! LYAR_HUMAN-Phosphoserine244 relationship: transforms_into CCO:B0067798 ! LYAR_HUMAN-Phosphoserine258 relationship: transforms_into CCO:B0067799 ! LYAR_HUMAN-Phosphoserine276 [Term] id: CCO:B0063384 name: MA2A2_HUMAN def: "Alpha-mannosidase 2x" [UniProtKB:P49641] synonym: "Alpha-mannosidase IIx" EXACT [UniProtKB:P49641] synonym: "EC 3.2.1.114" EXACT [UniProtKB:P49641] synonym: "MAN IIx" EXACT [UniProtKB:P49641] synonym: "Mannosidase alpha class 2A member 2" EXACT [UniProtKB:P49641] synonym: "Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase" EXACT [UniProtKB:P49641] xref: EMBL:AAA92022.1 xref: EMBL:BAA09510.1 xref: UniProtKB:P49641 xref: UniProtKB:Q13754 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022385 ! MAN2A2_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000944 ! alpha-mannosidase activity relationship: has_function CCO:F0000955 ! mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003018 ! mannosidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0004356 ! carbohydrate binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019761 ! man2a2-chd3 physical interaction relationship: participates_in CCO:I0020065 ! man2a2-git1 physical interaction relationship: participates_in CCO:I0020066 ! man2a2-ikbkap physical interaction [Term] id: CCO:B0063385 name: RM44_HUMAN def: "39S ribosomal protein L44, mitochondrial precursor" [UniProtKB:Q9H9J2] synonym: "EC 3.1.26.-" EXACT [UniProtKB:Q9H9J2] synonym: "L44mt" EXACT [UniProtKB:Q9H9J2] synonym: "MRP-L44" EXACT [UniProtKB:Q9H9J2] xref: EMBL:AAH12058.1 xref: EMBL:AAY14925.1 xref: EMBL:BAB14234.1 xref: EMBL:BAB14802.1 xref: EMBL:CAG33574.1 xref: UniProtKB:Q53S16 xref: UniProtKB:Q6IA62 xref: UniProtKB:Q9H821 xref: UniProtKB:Q9H9J2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022588 ! MRPL44_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000921 ! ribonuclease III activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0019768 ! mrpl44-setdb1 physical interaction relationship: transforms_into CCO:B0070092 ! RM44_HUMAN-Phosphoserine251 relationship: transforms_into CCO:B0070093 ! RM44_HUMAN-Phosphoserine255 [Term] id: CCO:B0063386 name: NP1L5_HUMAN def: "Nucleosome assembly protein 1-like 5" [UniProtKB:Q96NT1] xref: EMBL:AAI04884.1 xref: EMBL:BAB70793.1 xref: EMBL:EAX06025.1 xref: UniProtKB:Q96NT1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0006041 ! NAP1L5_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0008278 ! nap1l5-ptn physical interaction relationship: participates_in CCO:I0019770 ! nap1l5-htatip physical interaction [Term] id: CCO:B0063387 name: PUR6_HUMAN def: "Multifunctional protein ADE2" [UniProtKB:P22234] xref: EMBL:AAH10273.1 xref: EMBL:AAH19255.1 xref: EMBL:AAP35634.1 xref: EMBL:CAA37801.1 xref: UniProtKB:P22234 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022544 ! PAICS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019777 ! paics-chd3 physical interaction relationship: transforms_into CCO:B0069634 ! PUR6_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0069635 ! PUR6_HUMAN-Phosphoserine27 [Term] id: CCO:B0063388 name: PEX2_HUMAN def: "Peroxisome assembly factor 1" [UniProtKB:P28328] synonym: "35 kDa peroxisomal membrane protein" EXACT [UniProtKB:P28328] synonym: "PAF-1" EXACT [UniProtKB:P28328] synonym: "Peroxin-2" EXACT [UniProtKB:P28328] synonym: "Peroxisomal membrane protein 3" EXACT [UniProtKB:P28328] synonym: "RING finger protein 72" EXACT [UniProtKB:P28328] xref: EMBL:AAA60141.1 xref: EMBL:AAC12785.1 xref: EMBL:AAF97687.1 xref: EMBL:AAH05375.1 xref: EMBL:AAH93043.1 xref: UniProtKB:P28328 xref: UniProtKB:Q567S6 xref: UniProtKB:Q9BW41 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022504 ! PXMP3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000361 ! integral to peroxisomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019807 ! pxmp3-tle1 physical interaction [Term] id: CCO:B0063389 name: T4S1_HUMAN def: "Transmembrane 4 L6 family member 1" [UniProtKB:P30408] synonym: "M3S1" EXACT [UniProtKB:P30408] synonym: "Membrane component surface marker 1" EXACT [UniProtKB:P30408] synonym: "Tumor-associated antigen L6" EXACT [UniProtKB:P30408] xref: EMBL:AAA36158.1 xref: EMBL:AAH08442.1 xref: EMBL:AAH10166.1 xref: EMBL:CAG33234.1 xref: UniProtKB:P30408 xref: UniProtKB:Q6IB51 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022698 ! TM4SF1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019861 ! tm4sf1-ddr1 physical interaction [Term] id: CCO:B0063390 name: TMPS3_HUMAN def: "Transmembrane protease, serine 3" [UniProtKB:P57727] synonym: "EC 3.4.21.-" EXACT [UniProtKB:P57727] synonym: "Serine protease TADG-12" EXACT [UniProtKB:P57727] synonym: "Tumor-associated differentially-expressed gene 12 protein" EXACT [UniProtKB:P57727] xref: EMBL:AAG37012.1 xref: EMBL:AAH74846.1 xref: EMBL:AAH74847.1 xref: EMBL:AAQ88823.1 xref: EMBL:BAB20077.1 xref: EMBL:BAB20078.1 xref: EMBL:BAB20079.1 xref: EMBL:BAB20080.1 xref: EMBL:BAD18806.1 xref: UniProtKB:P57727 xref: UniProtKB:Q6ZMC3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022725 ! TMPRSS3_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001365 ! scavenger receptor activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003551 ! sodium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019862 ! tmprss3-rxra physical interaction [Term] id: CCO:B0063391 name: UBE2B_HUMAN def: "Ubiquitin-conjugating enzyme E2 B" [UniProtKB:P63146] synonym: "E2-17 kDa" EXACT [UniProtKB:P63146] synonym: "EC 6.3.2.19" EXACT [UniProtKB:P63146] synonym: "hHR6B" EXACT [UniProtKB:P63146] synonym: "HR6B" EXACT [UniProtKB:P63146] synonym: "Ubiquitin carrier protein B" EXACT [UniProtKB:P63146] synonym: "Ubiquitin-protein ligase B" EXACT [UniProtKB:P63146] xref: EMBL:AAA35982.1 xref: EMBL:AAH05979.1 xref: EMBL:AAH08404.1 xref: EMBL:AAH08470.1 xref: EMBL:AAP35734.1 xref: EMBL:AAY68224.1 xref: EMBL:CAA37339.1 xref: EMBL:CAG28562.1 xref: UniProtKB:P23567 xref: UniProtKB:P63146 xref: UniProtKB:Q4PJ15 xref: UniProtKB:Q9D0J6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022755 ! UBE2B_human relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0019872 ! ube2b-med31 physical interaction [Term] id: CCO:B0063392 name: ASAH1_HUMAN def: "Acid ceramidase precursor" [UniProtKB:Q13510] synonym: "AC" EXACT [UniProtKB:Q13510] synonym: "Acylsphingosine deacylase" EXACT [UniProtKB:Q13510] synonym: "EC 3.5.1.23" EXACT [UniProtKB:Q13510] synonym: "N-acylsphingosine amidohydrolase" EXACT [UniProtKB:Q13510] synonym: "PHP32" EXACT [UniProtKB:Q13510] synonym: "Putative 32 kDa heart protein" EXACT [UniProtKB:Q13510] xref: EMBL:AAC50907.1 xref: EMBL:AAC73009.1 xref: EMBL:AAF91230.1 xref: EMBL:AAH16481.1 xref: UniProtKB:Q13510 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022051 ! ASAH1_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003524 ! ceramidase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:I0019901 ! asah1-setdb1 physical interaction [Term] id: CCO:B0063393 name: FUND2_HUMAN def: "FUN14 domain-containing protein 2" [UniProtKB:Q9BWH2] synonym: "Cervical cancer proto-oncogene 3 protein" EXACT [UniProtKB:Q9BWH2] synonym: "HCC-3" EXACT [UniProtKB:Q9BWH2] synonym: "Hepatitis C virus core-binding protein 6" EXACT [UniProtKB:Q9BWH2] xref: EMBL:AAG44731.1 xref: EMBL:AAH00255.2 xref: EMBL:AAH72685.1 xref: EMBL:AAI08658.1 xref: EMBL:AAK51136.1 xref: EMBL:AAN51931.1 xref: EMBL:CAC81242.1 xref: EMBL:CAI41659.1 xref: EMBL:EAW72643.1 xref: UniProtKB:Q8NHX8 xref: UniProtKB:Q9BWH2 xref: UniProtKB:Q9H2I6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022262 ! FUNDC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019905 ! ascc2-fundc2 physical interaction relationship: participates_in CCO:I0020043 ! itgb3bp-fundc2 physical interaction relationship: participates_in CCO:I0020149 ! rgs1-fundc2 physical interaction relationship: participates_in CCO:I0020488 ! tp53i3-fundc2 physical interaction relationship: transforms_into CCO:B0066302 ! FUND2_HUMAN-Phosphoserine151 [Term] id: CCO:B0063394 name: PIN4_HUMAN def: "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4" [UniProtKB:Q9Y237] synonym: "EC 5.2.1.8" EXACT [UniProtKB:Q9Y237] synonym: "hPar14" EXACT [UniProtKB:Q9Y237] synonym: "Par14" EXACT [UniProtKB:Q9Y237] synonym: "Parvulin 14" EXACT [UniProtKB:Q9Y237] synonym: "Peptidyl-prolyl cis/trans isomerase EPVH" EXACT [UniProtKB:Q9Y237] synonym: "PPIase Pin4" EXACT [UniProtKB:Q9Y237] synonym: "Rotamase Pin4" EXACT [UniProtKB:Q9Y237] xref: EMBL:AAD27893.1 xref: EMBL:AAH05234.2 xref: EMBL:BAA82320.1 xref: EMBL:CAI39856.1 xref: UniProtKB:Q5HYW6 xref: UniProtKB:Q9Y237 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022516 ! PIN4_human relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: participates_in CCO:I0019908 ! ascc2-pin4 physical interaction relationship: participates_in CCO:I0020459 ! sptan1-pin4 physical interaction [Term] id: CCO:B0063395 name: ATPK_HUMAN def: "ATP synthase subunit f, mitochondrial" [UniProtKB:P56134] xref: EMBL:AAC34895.1 xref: EMBL:AAC39887.1 xref: EMBL:AAH03678.1 xref: EMBL:AAL06647.1 xref: UniProtKB:O76079 xref: UniProtKB:P56134 xref: UniProtKB:Q96L83 xref: UniProtKB:Q9BTI8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022060 ! ATP5J2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019917 ! atp5j2-aof2 physical interaction relationship: participates_in CCO:I0020251 ! atp5j2-arl10c physical interaction relationship: participates_in CCO:I0020252 ! atp5j2-capns1 physical interaction relationship: participates_in CCO:I0020253 ! atp5j2-zfpl1 physical interaction relationship: transforms_into CCO:B0065758 ! ATPK_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063396 name: VAS1_HUMAN def: "V-type proton ATPase subunit S1 precursor" [UniProtKB:Q15904] synonym: "Protein XAP-3" EXACT [UniProtKB:Q15904] synonym: "V-ATPase Ac45 subunit" EXACT [UniProtKB:Q15904] synonym: "V-ATPase S1 accessory protein" EXACT [UniProtKB:Q15904] synonym: "V-ATPase subunit S1" EXACT [UniProtKB:Q15904] synonym: "Vacuolar proton pump subunit S1" EXACT [UniProtKB:Q15904] xref: EMBL:AAH00724.1 xref: EMBL:BAA03938.1 xref: UniProtKB:Q15904 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022771 ! ATP6AP1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006277 ! hydrogen ion transporting ATP synthase activity, rotational mechanism relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000355 ! vacuole relationship: located_in CCO:C0000356 ! vacuolar membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: participates_in CCO:I0019918 ! atp6ap1-ang physical interaction [Term] id: CCO:B0063397 name: Q6ZUH1_HUMAN def: "cDNA FLJ43719 fis, clone TESOP2006060" [UniProtKB:Q6ZUH1] xref: EMBL:BAC86254.1 xref: UniProtKB:Q6ZUH1 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019922 ! q6zuh1-centa1 physical interaction [Term] id: CCO:B0063398 name: VPS11_HUMAN def: "Vacuolar protein sorting-associated protein 11 homolog" [UniProtKB:Q9H270] synonym: "hVPS11" EXACT [UniProtKB:Q9H270] synonym: "RING finger protein 108" EXACT [UniProtKB:Q9H270] xref: EMBL:AAG23761.1 xref: EMBL:AAG34677.1 xref: EMBL:AAH12051.1 xref: EMBL:AAH65563.1 xref: EMBL:BAA95163.2 xref: EMBL:BAB15320.1 xref: UniProtKB:Q8WY89 xref: UniProtKB:Q96EP8 xref: UniProtKB:Q9H270 xref: UniProtKB:Q9H6D9 xref: UniProtKB:Q9HCS6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022776 ! VPS11_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: participates_in CCO:I0019925 ! bcar1-vps11 physical interaction relationship: participates_in CCO:I0020685 ! vps11-tfap2b physical interaction [Term] id: CCO:B0063399 name: Q9NUW4_HUMAN def: "BRIX" [UniProtKB:Q9NUW4] synonym: "Brix domain containing 2, isoform CRA_b" EXACT [UniProtKB:Q9NUW4] synonym: "cDNA FLJ11100 fis, clone PLACE1005550" EXACT [UniProtKB:Q9NUW4] xref: EMBL:AAQ76802.1 xref: EMBL:BAA92003.1 xref: EMBL:EAW55910.1 xref: UniProtKB:Q9NUW4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022862 ! BXDC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019927 ! brix-setdb1 physical interaction [Term] id: CCO:B0063400 name: YLPM1_HUMAN def: "YLP motif-containing protein 1" [UniProtKB:P49750] synonym: "Nuclear protein ZAP3" EXACT [UniProtKB:P49750] synonym: "ZAP113" EXACT [UniProtKB:P49750] xref: EMBL:AAC42006.1 xref: EMBL:AAC42008.1 xref: EMBL:AAF61275.1 xref: EMBL:AAH07792.1 xref: UniProtKB:P49750 xref: UniProtKB:P49752 xref: UniProtKB:Q96I64 xref: UniProtKB:Q9P1V7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022791 ! YLPM1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019930 ! ylpm1-hrmt1l2 physical interaction relationship: transforms_into CCO:B0071928 ! YLPM1_HUMAN-Phosphoserine634 relationship: transforms_into CCO:B0071929 ! YLPM1_HUMAN-Phosphoserine924 [Term] id: CCO:B0063401 name: ORA2P_HUMAN def: "Putative protein ORAI2-2" [UniProtKB:Q9H9Y3] xref: EMBL:AAG23755.1 xref: EMBL:AAP22352.1 xref: EMBL:BAB14085.1 xref: EMBL:CAG33568.1 xref: UniProtKB:Q6IA68 xref: UniProtKB:Q8WY94 xref: UniProtKB:Q9H9Y3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022483 ! ORAI2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019932 ! c7orf19-gdf9 physical interaction relationship: participates_in CCO:I0019933 ! c7orf19-setdb1 physical interaction relationship: participates_in CCO:I0020261 ! c7orf19-med31 physical interaction [Term] id: CCO:B0063402 name: CI046_HUMAN def: "Transmembrane protein C9orf46" [UniProtKB:Q9HBL7] xref: EMBL:AAF67643.1 xref: EMBL:AAG09722.1 xref: EMBL:AAH08212.1 xref: EMBL:BAB55219.1 xref: EMBL:CAH70364.1 xref: UniProtKB:Q9HBL7 xref: UniProtKB:Q9NZ44 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022124 ! C9orf46_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0019935 ! c9orf46-g22p1 physical interaction [Term] id: CCO:B0063403 name: COMD3_HUMAN def: "COMM domain-containing protein 3" [UniProtKB:Q9UBI1] synonym: "Protein Bup" EXACT [UniProtKB:Q9UBI1] synonym: "Protein PIL" EXACT [UniProtKB:Q9UBI1] xref: EMBL:AAD44480.1 xref: EMBL:AAF17240.1 xref: EMBL:AAH22898.1 xref: EMBL:AAS22241.1 xref: UniProtKB:Q9UBI1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022145 ! COMMD3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019949 ! commd3-znf337 physical interaction [Term] id: CCO:B0063404 name: APOM_HUMAN def: "Apolipoprotein M" [UniProtKB:O95445] synonym: "Apo-M" EXACT [UniProtKB:O95445] synonym: "ApoM" EXACT [UniProtKB:O95445] synonym: "Protein G3a" EXACT [UniProtKB:O95445] xref: EMBL:AAD11443.2 xref: EMBL:AAD18084.1 xref: EMBL:AAF29014.1 xref: EMBL:AAH20683.1 xref: EMBL:BAB63389.1 xref: EMBL:CAB51604.1 xref: EMBL:CAI17788.1 xref: EMBL:CAI18319.1 xref: EMBL:CAI18511.1 xref: UniProtKB:O95445 xref: UniProtKB:Q9P046 xref: UniProtKB:Q9UMP6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022045 ! APOM_human relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: participates_in CCO:I0019950 ! klf6-apom physical interaction [Term] id: CCO:B0063405 name: CD017_HUMAN def: "Uncharacterized protein C4orf17" [UniProtKB:Q53FE4] xref: EMBL:AAH69805.1 xref: EMBL:AAH74759.1 xref: EMBL:BAD97065.1 xref: EMBL:CAB66772.1 xref: EMBL:CAG38573.1 xref: UniProtKB:Q53FE4 xref: UniProtKB:Q6FI84 xref: UniProtKB:Q6IS77 xref: UniProtKB:Q9H0D9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022105 ! C4orf17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019968 ! c4orf17-chd3 physical interaction relationship: participates_in CCO:I0019969 ! c4orf17-sh3gl3 physical interaction [Term] id: CCO:B0063406 name: GP183_HUMAN def: "G-protein coupled receptor 183" [UniProtKB:P32249] synonym: "EBV-induced G-protein coupled receptor 2" EXACT [UniProtKB:P32249] xref: EMBL:AAA35924.1 xref: EMBL:AAH20752.1 xref: EMBL:BAD97110.1 xref: EMBL:BAF84780.1 xref: EMBL:BAG36232.1 xref: EMBL:CAI14308.1 xref: EMBL:EAX09018.1 xref: UniProtKB:B2R8N5 xref: UniProtKB:P32249 xref: UniProtKB:Q53F99 xref: UniProtKB:Q5JUH7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022286 ! GPR183_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019982 ! ebi2-mta1 physical interaction [Term] id: CCO:B0063407 name: EIF3M_HUMAN def: "Eukaryotic translation initiation factor 3 subunit M" [UniProtKB:Q7L2H7] synonym: "eIF3m" EXACT [UniProtKB:Q7L2H7] synonym: "Fetal lung protein B5" EXACT [UniProtKB:Q7L2H7] synonym: "hFL-B5" EXACT [UniProtKB:Q7L2H7] synonym: "PCI domain-containing protein 1" EXACT [UniProtKB:Q7L2H7] xref: EMBL:AAC17108.1 xref: EMBL:AAH19103.1 xref: EMBL:AAH51292.1 xref: EMBL:AAK07542.1 xref: EMBL:AAX12524.1 xref: EMBL:ABD14422.1 xref: EMBL:BAD96284.1 xref: EMBL:CAG29296.1 xref: EMBL:EAW68217.1 xref: UniProtKB:O60735 xref: UniProtKB:Q2F836 xref: UniProtKB:Q53HL6 xref: UniProtKB:Q7L2H7 xref: UniProtKB:Q9BXW1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022215 ! EIF3M_human relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019984 ! eif3s5-ga17 physical interaction relationship: transforms_into CCO:B0065989 ! EIF3M_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0065990 ! EIF3M_HUMAN-Phosphoserine337 relationship: transforms_into CCO:B0065991 ! EIF3M_HUMAN-Phosphotyrosine351 [Term] id: CCO:B0063408 name: Q76MU0_HUMAN def: "Cortactin" [UniProtKB:Q76MU0] xref: EMBL:BAD06416.1 xref: UniProtKB:Q76MU0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022842 ! EMS1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0019988 ! ems1-chd3 physical interaction [Term] id: CCO:B0063409 name: DC1L2_HUMAN def: "Cytoplasmic dynein 1 light intermediate chain 2" [UniProtKB:O43237] synonym: "Dynein light intermediate chain 2, cytosolic" EXACT [UniProtKB:O43237] synonym: "LIC-2" EXACT [UniProtKB:O43237] synonym: "LIC53/55" EXACT [UniProtKB:O43237] xref: EMBL:AAB88513.1 xref: EMBL:AAH25959.1 xref: UniProtKB:O43237 xref: UniProtKB:Q8TAT3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022170 ! DYNC1LI2_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000428 ! cytoplasmic dynein complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000995 ! dynein complex relationship: participates_in CCO:I0019990 ! epb49-dncli2 physical interaction relationship: transforms_into CCO:B0065923 ! DC1L2_HUMAN-Phosphoserine194 relationship: transforms_into CCO:B0065924 ! DC1L2_HUMAN-Phosphoserine446 [Term] id: CCO:B0063410 name: MYO15_HUMAN def: "Myosin-XV" [UniProtKB:Q9UKN7] synonym: "Unconventional myosin-15" EXACT [UniProtKB:Q9UKN7] xref: EMBL:AAF05903.1 xref: UniProtKB:Q9UKN7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022417 ! MYO15A_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0001706 ! cell projection relationship: participates_in CCO:I0019992 ! eps8-myo15a physical interaction [Term] id: CCO:B0063411 name: F176A_HUMAN def: "Protein FAM176A" [UniProtKB:Q9H8M9] synonym: "Transmembrane protein 166" EXACT [UniProtKB:Q9H8M9] xref: EMBL:AAG17981.1 xref: EMBL:AAH16157.1 xref: EMBL:AAH63016.1 xref: EMBL:AAY14774.1 xref: EMBL:BAB14580.1 xref: EMBL:CAG33595.1 xref: UniProtKB:Q9H8M9 xref: UniProtKB:Q9HC41 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022241 ! FAM176A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0008233 ! flj13391-ptn physical interaction [Term] id: CCO:B0063412 name: PR38A_HUMAN def: "Pre-mRNA-splicing factor 38A" [UniProtKB:Q8NAV1] xref: EMBL:AAH00777.2 xref: EMBL:AAH63655.1 xref: EMBL:AAI05005.1 xref: EMBL:AAI05007.1 xref: EMBL:BAB55405.1 xref: EMBL:BAC03796.1 xref: EMBL:CAI12289.1 xref: UniProtKB:Q8NAV1 xref: UniProtKB:Q96JW1 xref: UniProtKB:Q9BVZ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022526 ! PRPF38A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020003 ! rp5_965l7_1-pola2 physical interaction relationship: transforms_into CCO:B0069466 ! PR38A_HUMAN-Phosphoserine182 relationship: transforms_into CCO:B0069467 ! PR38A_HUMAN-Phosphoserine193 relationship: transforms_into CCO:B0069468 ! PR38A_HUMAN-Phosphoserine194 relationship: transforms_into CCO:B0069469 ! PR38A_HUMAN-Phosphoserine209 relationship: transforms_into CCO:B0069470 ! PR38A_HUMAN-Phosphoserine226 relationship: transforms_into CCO:B0069471 ! PR38A_HUMAN-Phosphothreonine228 relationship: transforms_into CCO:B0069472 ! PR38A_HUMAN-Phosphoserine260 relationship: transforms_into CCO:B0069473 ! PR38A_HUMAN-Phosphoserine262 relationship: transforms_into CCO:B0069474 ! PR38A_HUMAN-Phosphoserine279 relationship: transforms_into CCO:B0069475 ! PR38A_HUMAN-Phosphoserine281 [Term] id: CCO:B0063413 name: CH033_HUMAN def: "UPF0488 protein C8orf33" [UniProtKB:Q9H7E9] xref: EMBL:AAH10001.1 xref: EMBL:AAH15181.1 xref: EMBL:BAB14943.1 xref: EMBL:CAG33611.1 xref: EMBL:EAW82023.1 xref: UniProtKB:A6NGC0 xref: UniProtKB:Q96BT8 xref: UniProtKB:Q9H7E9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022118 ! C8orf33_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020004 ! c8orf33-git1 physical interaction [Term] id: CCO:B0063414 name: FUS_HUMAN def: "RNA-binding protein FUS" [UniProtKB:P35637] synonym: "75 kDa DNA-pairing protein" EXACT [UniProtKB:P35637] synonym: "Oncogene FUS" EXACT [UniProtKB:P35637] synonym: "Oncogene TLS" EXACT [UniProtKB:P35637] synonym: "POMp75" EXACT [UniProtKB:P35637] synonym: "Translocated in liposarcoma protein" EXACT [UniProtKB:P35637] xref: EMBL:AAB27102.1 xref: EMBL:AAB27103.1 xref: EMBL:AAC35284.1 xref: EMBL:AAC35285.1 xref: EMBL:AAH00402.1 xref: EMBL:AAH02459.1 xref: EMBL:CAA50558.1 xref: EMBL:CAA50559.1 xref: UniProtKB:P35637 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022263 ! FUS_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020006 ! fus-hrmt1l2 physical interaction relationship: transforms_into CCO:B0066317 ! FUS_HUMAN-Omega-N-methylated arginine216 relationship: transforms_into CCO:B0066318 ! FUS_HUMAN-Omega-N-methylated arginine218 [Term] id: CCO:B0063415 name: GEMI7_HUMAN def: "Gem-associated protein 7" [UniProtKB:Q9H840] synonym: "Gemin-7" EXACT [UniProtKB:Q9H840] synonym: "SIP3" EXACT [UniProtKB:Q9H840] xref: EMBL:AAH07793.1 xref: EMBL:AAM44083.1 xref: EMBL:BAB14780.1 xref: UniProtKB:Q9H840 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022274 ! GEMIN7_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000817 ! nuclear body relationship: participates_in CCO:I0020009 ! gemin7-htatip physical interaction [Term] id: CCO:B0063416 name: CC113_HUMAN def: "Coiled-coil domain-containing protein 113" [UniProtKB:Q9H0I3] xref: EMBL:AAF29037.1 xref: EMBL:AAI26446.1 xref: EMBL:AAI26448.1 xref: EMBL:CAB66719.1 xref: EMBL:CAG38537.1 xref: UniProtKB:Q9H0I3 xref: UniProtKB:Q9NZX2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022095 ! CCDC113_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001750 ! protein complex relationship: participates_in CCO:I0020034 ! dkfzp434n1418-git1 physical interaction relationship: participates_in CCO:I0020035 ! dkfzp434n1418-pfn2 physical interaction [Term] id: CCO:B0063417 name: KCD15_HUMAN def: "BTB/POZ domain-containing protein KCTD15" [UniProtKB:Q96SI1] xref: EMBL:AAH01185.1 xref: EMBL:AAH09335.1 xref: EMBL:BAB55443.1 xref: UniProtKB:Q96SI1 xref: UniProtKB:Q9BVI6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022349 ! KCTD15_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020050 ! kctd15-ren physical interaction relationship: participates_in CCO:I0020580 ! kctd15-rfp physical interaction relationship: transforms_into CCO:B0067281 ! KCD15_HUMAN-Phosphoserine31 relationship: transforms_into CCO:B0067282 ! KCD15_HUMAN-Phosphoserine35 relationship: transforms_into CCO:B0067283 ! KCD15_HUMAN-Phosphoserine38 [Term] id: CCO:B0063418 name: PPA5_HUMAN def: "Tartrate-resistant acid phosphatase type 5 precursor" [UniProtKB:P13686] synonym: "Acid phosphatase 5, tartrate resistant" EXACT [UniProtKB:P13686] synonym: "EC 3.1.3.2" EXACT [UniProtKB:P13686] synonym: "Tartrate-resistant acid ATPase" EXACT [UniProtKB:P13686] synonym: "TR-AP" EXACT [UniProtKB:P13686] synonym: "TrATPase" EXACT [UniProtKB:P13686] xref: EMBL:AAA76849.1 xref: EMBL:AAH25414.1 xref: EMBL:AAI11015.1 xref: EMBL:CAA32771.1 xref: EMBL:CAG33359.1 xref: UniProtKB:P13686 xref: UniProtKB:Q2TAB1 xref: UniProtKB:Q6IAS6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022523 ! ACP5_human relationship: has_function CCO:F0000478 ! acid phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020067 ! mapk9-acp5 physical interaction relationship: participates_in CCO:I0020097 ! pdcd5-acp5 physical interaction relationship: participates_in CCO:I0020299 ! egr2-acp5 physical interaction relationship: participates_in CCO:I0020440 ! rpa2-acp5 physical interaction relationship: participates_in CCO:I0020484 ! tnfsf10-acp5 physical interaction [Term] id: CCO:B0063419 name: PGAM5_HUMAN def: "Phosphoglycerate mutase family member 5 precursor" [UniProtKB:Q96HS1] synonym: "Bcl-XL-binding protein v68" EXACT [UniProtKB:Q96HS1] xref: EMBL:AAH08196.1 xref: EMBL:AAK60627.1 xref: UniProtKB:Q96HS1 xref: UniProtKB:Q96JB0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022508 ! PGAM5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020071 ! mgc5352-hspa1a physical interaction relationship: participates_in CCO:I0020072 ! mgc5352-setdb1 physical interaction [Term] id: CCO:B0063420 name: Q6FID1_HUMAN def: "MRPL42 protein (Mitochondrial ribosomal protein L42, isoform CRA_b)" [UniProtKB:Q6FID1] xref: EMBL:CAG38526.1 xref: EMBL:EAW97484.1 xref: UniProtKB:Q6FID1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022835 ! MRPL42_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020076 ! mrpl42-ikbkap physical interaction [Term] id: CCO:B0063421 name: MYL9_HUMAN def: "Myosin regulatory light polypeptide 9" [UniProtKB:P24844] synonym: "LC20" EXACT [UniProtKB:P24844] synonym: "MLC-2C" EXACT [UniProtKB:P24844] synonym: "Myosin regulatory light chain 2, smooth muscle isoform" EXACT [UniProtKB:P24844] synonym: "Myosin regulatory light chain 9" EXACT [UniProtKB:P24844] synonym: "Myosin regulatory light chain MRLC1" EXACT [UniProtKB:P24844] synonym: "Myosin RLC" EXACT [UniProtKB:P24844] xref: EMBL:AAA59852.1 xref: EMBL:BAB88917.1 xref: EMBL:CAB75369.1 xref: UniProtKB:P24844 xref: UniProtKB:Q9H136 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022416 ! MYL9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020079 ! myh9-myl9 physical interaction relationship: transforms_into CCO:B0068377 ! MYL9_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0068378 ! MYL9_HUMAN-Phosphothreonine19 relationship: transforms_into CCO:B0068379 ! MYL9_HUMAN-Phosphoserine20 relationship: transforms_into CCO:B0068380 ! MYL9_HUMAN-Phosphoserine29 relationship: transforms_into CCO:B0068381 ! MYL9_HUMAN-Phosphothreonine135 [Term] id: CCO:B0063422 name: NDUA6_HUMAN def: "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6" [UniProtKB:P56556] synonym: "CI-B14" EXACT [UniProtKB:P56556] synonym: "Complex I-B14" EXACT [UniProtKB:P56556] synonym: "LYR motif-containing protein 6" EXACT [UniProtKB:P56556] synonym: "NADH-ubiquinone oxidoreductase B14 subunit" EXACT [UniProtKB:P56556] xref: EMBL:AAC04267.1 xref: EMBL:AAH02772.1 xref: EMBL:CAG30415.1 xref: EMBL:CAI19953.1 xref: UniProtKB:O43675 xref: UniProtKB:P56556 xref: UniProtKB:Q6IC39 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022435 ! NDUFA6_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020082 ! ndufa6-tbpl1 physical interaction relationship: transforms_into CCO:B0068547 ! NDUA6_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063423 name: NDUB9_HUMAN def: "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9" [UniProtKB:Q9Y6M9] synonym: "CI-B22" EXACT [UniProtKB:Q9Y6M9] synonym: "Complex I-B22" EXACT [UniProtKB:Q9Y6M9] synonym: "LYR motif-containing protein 3" EXACT [UniProtKB:Q9Y6M9] synonym: "NADH-ubiquinone oxidoreductase B22 subunit" EXACT [UniProtKB:Q9Y6M9] xref: EMBL:AAD32452.1 xref: EMBL:AAD42057.1 xref: EMBL:AAF99683.1 xref: EMBL:AAH07672.1 xref: UniProtKB:Q9UQE8 xref: UniProtKB:Q9Y6M9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022438 ! NDUFB9_human relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020084 ! ndufb9-ikbkap physical interaction relationship: participates_in CCO:I0020085 ! ndufb9-sh3gl3 physical interaction relationship: participates_in CCO:I0020382 ! ndufb9-gdf9 physical interaction relationship: transforms_into CCO:B0068551 ! NDUB9_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063424 name: NDUV2_HUMAN def: "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial precursor" [UniProtKB:P19404] synonym: "EC 1.6.5.3" EXACT [UniProtKB:P19404] synonym: "EC 1.6.99.3" EXACT [UniProtKB:P19404] synonym: "NADH-ubiquinone oxidoreductase 24 kDa subunit" EXACT [UniProtKB:P19404] xref: EMBL:AAA75390.1 xref: EMBL:AAH01632.1 xref: EMBL:AAH17487.1 xref: UniProtKB:P19404 xref: UniProtKB:Q9BV41 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022442 ! NDUFV2_human relationship: has_function CCO:F0000447 ! NADH dehydrogenase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008139 ! 2 iron, 2 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020086 ! ndufv2-htatip physical interaction relationship: participates_in CCO:I0020383 ! ndufv2-sp110 physical interaction [Term] id: CCO:B0063425 name: THOC7_HUMAN def: "THO complex subunit 7 homolog" [UniProtKB:Q6I9Y2] synonym: "Ngg1-interacting factor 3-like protein 1-binding protein 1" EXACT [UniProtKB:Q6I9Y2] synonym: "NIF3L1-binding protein 1" EXACT [UniProtKB:Q6I9Y2] xref: EMBL:AAH20599.2 xref: EMBL:AAH65012.1 xref: EMBL:BAB15656.1 xref: EMBL:CAG33654.1 xref: EMBL:EAW65418.1 xref: UniProtKB:Q6I9Y2 xref: UniProtKB:Q6P1L3 xref: UniProtKB:Q8WUF2 xref: UniProtKB:Q9H5H0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022712 ! THOC7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020089 ! nif3l1bp1-chd3 physical interaction [Term] id: CCO:B0063426 name: NPS3A_HUMAN def: "Protein NipSnap homolog 3A" [UniProtKB:Q9UFN0] synonym: "NipSnap3A" EXACT [UniProtKB:Q9UFN0] synonym: "NipSnap4" EXACT [UniProtKB:Q9UFN0] synonym: "Target for Salmonella secreted protein C" EXACT [UniProtKB:Q9UFN0] synonym: "TassC" EXACT [UniProtKB:Q9UFN0] xref: EMBL:AAF28977.1 xref: EMBL:AAH05935.1 xref: EMBL:BAB14777.1 xref: EMBL:CAB55992.2 xref: EMBL:CAH73580.1 xref: EMBL:EAW58990.1 xref: UniProtKB:A6NM55 xref: UniProtKB:Q5VX32 xref: UniProtKB:Q9BRV7 xref: UniProtKB:Q9H843 xref: UniProtKB:Q9P083 xref: UniProtKB:Q9UFN0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022454 ! NIPSNAP3A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020090 ! nipsnap3a-ikbkap physical interaction relationship: participates_in CCO:I0020091 ! nipsnap3a-setdb1 physical interaction [Term] id: CCO:B0063427 name: NIT1_HUMAN def: "Nitrilase homolog 1" [UniProtKB:Q86X76] synonym: "EC 3.5.-.-" EXACT [UniProtKB:Q86X76] xref: EMBL:AAC39901.1 xref: EMBL:AAC39907.1 xref: EMBL:AAH46149.1 xref: EMBL:CAG46613.1 xref: EMBL:CAG46644.1 xref: UniProtKB:O76091 xref: UniProtKB:Q86X76 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022446 ! NIT1_human relationship: has_function CCO:F0000053 ! nitrilase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020092 ! nit1-g22p1 physical interaction [Term] id: CCO:B0063428 name: PRG2_HUMAN def: "Bone marrow proteoglycan precursor" [UniProtKB:P13727] synonym: "BMPG" EXACT [UniProtKB:P13727] synonym: "Proteoglycan 2" EXACT [UniProtKB:P13727] xref: EMBL:AAA35796.1 xref: EMBL:AAA35965.1 xref: EMBL:AAA36203.1 xref: EMBL:AAH05929.1 xref: EMBL:CAA32250.1 xref: EMBL:CAA46670.1 xref: EMBL:CAA68751.1 xref: EMBL:CAA81207.1 xref: EMBL:CAG29307.1 xref: UniProtKB:P13727 xref: UniProtKB:P81448 xref: UniProtKB:Q14227 xref: UniProtKB:Q6ICT2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022529 ! PRG2_human relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0020128 ! prg2-chd3 physical interaction [Term] id: CCO:B0063429 name: TGT_HUMAN def: "Queuine tRNA-ribosyltransferase" [UniProtKB:Q9BXR0] synonym: "EC 2.4.2.29" EXACT [UniProtKB:Q9BXR0] synonym: "Guanine insertion enzyme" EXACT [UniProtKB:Q9BXR0] synonym: "tRNA-guanine transglycosylase" EXACT [UniProtKB:Q9BXR0] xref: EMBL:AAG60033.1 xref: EMBL:AAG60034.1 xref: EMBL:AAH15350.1 xref: UniProtKB:Q96BQ4 xref: UniProtKB:Q9BXQ9 xref: UniProtKB:Q9BXR0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022709 ! QTRT1_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001940 ! queuine tRNA-ribosyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000407 ! ribosome relationship: participates_in CCO:I0020135 ! qtrt1-setdb1 physical interaction relationship: participates_in CCO:I0020136 ! qtrt1-sh3gl3 physical interaction [Term] id: CCO:B0063430 name: RIFK_HUMAN def: "Riboflavin kinase" [UniProtKB:Q969G6] synonym: "ATP:riboflavin 5'-phosphotransferase" EXACT [UniProtKB:Q969G6] synonym: "EC 2.7.1.26" EXACT [UniProtKB:Q969G6] synonym: "Flavokinase" EXACT [UniProtKB:Q969G6] xref: EMBL:AAH07069.1 xref: EMBL:BAA92033.1 xref: EMBL:CAI40676.1 xref: UniProtKB:Q5JSG9 xref: UniProtKB:Q969G6 xref: UniProtKB:Q9NUT7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022568 ! RFK_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001981 ! riboflavin kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0020137 ! rab1a-rfk physical interaction [Term] id: CCO:B0063431 name: Q5STK0_HUMAN def: "Ral guanine nucleotide dissociation stimulator-like 2 (Ral guanine nucleotide dissociation stimulator-like 2, isoform CRA_b)" [UniProtKB:Q5STK0] xref: EMBL:CAI17521.1 xref: EMBL:CAI18118.1 xref: EMBL:CAI41832.1 xref: EMBL:CAQ08027.1 xref: EMBL:CAQ08257.1 xref: EMBL:EAX03709.1 xref: UniProtKB:Q5STK0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0019694 ! RGL2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020143 ! rgl2-htatip physical interaction relationship: participates_in CCO:I0020144 ! rgl2-myst2 physical interaction [Term] id: CCO:B0063432 name: RER1_HUMAN def: "Protein RER1" [UniProtKB:O15258] xref: EMBL:AAC72940.1 xref: EMBL:AAH04965.1 xref: EMBL:CAA04754.1 xref: UniProtKB:O15258 xref: UniProtKB:O95322 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022565 ! RER1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000988 ! integral to Golgi membrane relationship: participates_in CCO:I0020147 ! rer1-sh3gl3 physical interaction relationship: transforms_into CCO:B0069879 ! RER1_HUMAN-Phosphoserine95 [Term] id: CCO:B0063433 name: EDEM2_HUMAN def: "ER degradation-enhancing alpha-mannosidase-like 2 precursor" [UniProtKB:Q9BV94] xref: EMBL:AAH01371.1 xref: EMBL:AAH16184.1 xref: EMBL:AAQ88943.1 xref: EMBL:BAA91806.1 xref: EMBL:BAB14731.1 xref: EMBL:CAG33547.1 xref: EMBL:CAH73763.1 xref: EMBL:CAI19292.1 xref: UniProtKB:Q6GU33 xref: UniProtKB:Q6IA89 xref: UniProtKB:Q6UWZ4 xref: UniProtKB:Q9BV94 xref: UniProtKB:Q9H4U0 xref: UniProtKB:Q9H886 xref: UniProtKB:Q9NTL9 xref: UniProtKB:Q9NVE6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022211 ! EDEM2_human relationship: has_function CCO:F0000954 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020154 ! rps3a-c20orf31 physical interaction [Term] id: CCO:B0063434 name: KLDC2_HUMAN def: "Kelch domain-containing protein 2" [UniProtKB:Q9Y2U9] synonym: "HCLP-1" EXACT [UniProtKB:Q9Y2U9] synonym: "Hepatocellular carcinoma-associated antigen 33" EXACT [UniProtKB:Q9Y2U9] synonym: "Host cell factor homolog LCP" EXACT [UniProtKB:Q9Y2U9] synonym: "Host cell factor-like protein 1" EXACT [UniProtKB:Q9Y2U9] xref: EMBL:AAD21038.1 xref: EMBL:AAF66246.1 xref: EMBL:AAH02335.1 xref: EMBL:AAH24192.1 xref: EMBL:BAA91898.1 xref: EMBL:CAD61901.1 xref: EMBL:CAG33486.1 xref: EMBL:EAW65750.1 xref: UniProtKB:Q6IAF0 xref: UniProtKB:Q86TY9 xref: UniProtKB:Q9Y2U9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022354 ! KLHDC2_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020176 ! strn4-klhdc2 physical interaction [Term] id: CCO:B0063435 name: SYN1_HUMAN def: "Synapsin-1" [UniProtKB:P17600] synonym: "Brain protein 4.1" EXACT [UniProtKB:P17600] synonym: "Synapsin I" EXACT [UniProtKB:P17600] xref: EMBL:AAA60608.1 xref: EMBL:AAC41930.1 xref: EMBL:AAC41931.1 xref: EMBL:CAI42446.1 xref: EMBL:CAI42462.1 xref: UniProtKB:O75825 xref: UniProtKB:P17600 xref: UniProtKB:Q5H9A9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022694 ! SYN1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020179 ! syn1-htatip physical interaction relationship: transforms_into CCO:B0071044 ! SYN1_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0071045 ! SYN1_HUMAN-Phosphoserine39 relationship: transforms_into CCO:B0071046 ! SYN1_HUMAN-Phosphoserine62 relationship: transforms_into CCO:B0071047 ! SYN1_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0071048 ! SYN1_HUMAN-Phosphotyrosine312 relationship: transforms_into CCO:B0071049 ! SYN1_HUMAN-Phosphothreonine337 relationship: transforms_into CCO:B0071050 ! SYN1_HUMAN-Phosphoserine427 relationship: transforms_into CCO:B0071051 ! SYN1_HUMAN-Phosphoserine510 relationship: transforms_into CCO:B0071052 ! SYN1_HUMAN-Phosphothreonine512 relationship: transforms_into CCO:B0071053 ! SYN1_HUMAN-Phosphoserine520 relationship: transforms_into CCO:B0071054 ! SYN1_HUMAN-Phosphoserine551 relationship: transforms_into CCO:B0071055 ! SYN1_HUMAN-Phosphoserine553 relationship: transforms_into CCO:B0071056 ! SYN1_HUMAN-Phosphoserine568 relationship: transforms_into CCO:B0071057 ! SYN1_HUMAN-Phosphoserine605 relationship: transforms_into CCO:B0071058 ! SYN1_HUMAN-Phosphoserine665 relationship: transforms_into CCO:B0071059 ! SYN1_HUMAN-Phosphoserine704 [Term] id: CCO:B0063436 name: TR10C_HUMAN def: "Tumor necrosis factor receptor superfamily member 10C precursor" [UniProtKB:O14798] synonym: "Antagonist decoy receptor for TRAIL/Apo-2L" EXACT [UniProtKB:O14798] synonym: "CD263 antigen" EXACT [UniProtKB:O14798] synonym: "DcR1" EXACT [UniProtKB:O14798] synonym: "Decoy receptor 1" EXACT [UniProtKB:O14798] synonym: "Decoy TRAIL receptor without death domain" EXACT [UniProtKB:O14798] synonym: "Lymphocyte inhibitor of TRAIL" EXACT [UniProtKB:O14798] synonym: "TNF-related apoptosis-inducing ligand receptor 3" EXACT [UniProtKB:O14798] synonym: "TRAIL receptor 3" EXACT [UniProtKB:O14798] synonym: "Trail receptor without an intracellular domain" EXACT [UniProtKB:O14798] synonym: "TRAIL-R3" EXACT [UniProtKB:O14798] xref: EMBL:AAB67104.1 xref: EMBL:AAB67110.1 xref: EMBL:AAB71413.1 xref: EMBL:AAB81181.1 xref: EMBL:AAB87506.1 xref: EMBL:AAC05593.1 xref: EMBL:AAI25042.1 xref: EMBL:AAI25043.1 xref: EMBL:AAQ88648.1 xref: EMBL:CAG46655.1 xref: UniProtKB:O14755 xref: UniProtKB:O14798 xref: UniProtKB:Q08AS6 xref: UniProtKB:Q6FH98 xref: UniProtKB:Q6UXM5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022731 ! TNFRSF10C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020200 ! tnfrsf10c-zhx1 physical interaction relationship: participates_in CCO:I0020482 ! tnfrsf10c-apoa1 physical interaction [Term] id: CCO:B0063437 name: Q6IBM8_HUMAN def: "U5-116KD protein" [UniProtKB:Q6IBM8] xref: EMBL:CAG33055.1 xref: UniProtKB:Q6IBM8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022838 ! U5-116KD_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020211 ! u5_116kd-arpc3 physical interaction [Term] id: CCO:B0063438 name: NDRG1_HUMAN def: "Protein NDRG1" [UniProtKB:Q92597] synonym: "Differentiation-related gene 1 protein" EXACT [UniProtKB:Q92597] synonym: "DRG-1" EXACT [UniProtKB:Q92597] synonym: "N-myc downstream-regulated gene 1 protein" EXACT [UniProtKB:Q92597] synonym: "Nickel-specific induction protein Cap43" EXACT [UniProtKB:Q92597] synonym: "Reducing agents and tunicamycin-responsive protein" EXACT [UniProtKB:Q92597] synonym: "Rit42" EXACT [UniProtKB:Q92597] synonym: "RTP" EXACT [UniProtKB:Q92597] xref: EMBL:AAC13419.1 xref: EMBL:AAF71305.1 xref: EMBL:AAH03175.1 xref: EMBL:BAA13505.1 xref: EMBL:CAA63430.1 xref: UniProtKB:O15207 xref: UniProtKB:Q92597 xref: UniProtKB:Q9NYR6 xref: UniProtKB:Q9UK29 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022434 ! NDRG1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020231 ! arf4l-ndrg1 physical interaction relationship: transforms_into CCO:B0068529 ! NDRG1_HUMAN-Phosphoserine319 relationship: transforms_into CCO:B0068530 ! NDRG1_HUMAN-Phosphoserine326 relationship: transforms_into CCO:B0068531 ! NDRG1_HUMAN-Phosphothreonine328 relationship: transforms_into CCO:B0068532 ! NDRG1_HUMAN-Phosphoserine330 relationship: transforms_into CCO:B0068533 ! NDRG1_HUMAN-Phosphoserine332 relationship: transforms_into CCO:B0068534 ! NDRG1_HUMAN-Phosphoserine333 relationship: transforms_into CCO:B0068535 ! NDRG1_HUMAN-Phosphothreonine335 relationship: transforms_into CCO:B0068536 ! NDRG1_HUMAN-Phosphoserine336 relationship: transforms_into CCO:B0068537 ! NDRG1_HUMAN-Phosphoserine364 relationship: transforms_into CCO:B0068538 ! NDRG1_HUMAN-Phosphothreonine366 relationship: transforms_into CCO:B0068539 ! NDRG1_HUMAN-Phosphothreonine375 [Term] id: CCO:B0063439 name: Q6IBM5_HUMAN def: "ARHGDIA protein" [UniProtKB:Q6IBM5] synonym: "Rho GDP dissociation inhibitor (GDI) alpha" EXACT [UniProtKB:Q6IBM5] synonym: "Rho GDP dissociation inhibitor (GDI) alpha, isoform CRA_a" EXACT [UniProtKB:Q6IBM5] xref: EMBL:AAI06045.1 xref: EMBL:CAG33058.1 xref: EMBL:EAW89697.1 xref: UniProtKB:Q6IBM5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0004692 ! ARHGDIA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020236 ! arhgdia-sh3gl3 physical interaction [Term] id: CCO:B0063440 name: RNAS6_HUMAN def: "Ribonuclease K6 precursor" [UniProtKB:Q93091] synonym: "EC 3.1.27.-" EXACT [UniProtKB:Q93091] synonym: "RNase K6" EXACT [UniProtKB:Q93091] xref: EMBL:AAC51848.1 xref: EMBL:AAH20848.1 xref: UniProtKB:Q93091 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022592 ! RNASE6_human relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000919 ! pancreatic ribonuclease activity relationship: has_function CCO:F0000934 ! ribonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: participates_in CCO:I0020239 ! arr3-rnase6 physical interaction [Term] id: CCO:B0063441 name: RNZ2_HUMAN def: "Zinc phosphodiesterase ELAC protein 2" [UniProtKB:Q9BQ52] synonym: "EC 3.1.26.11" EXACT [UniProtKB:Q9BQ52] synonym: "ElaC homolog protein 2" EXACT [UniProtKB:Q9BQ52] synonym: "Heredity prostate cancer protein 2" EXACT [UniProtKB:Q9BQ52] synonym: "Ribonuclease Z 2" EXACT [UniProtKB:Q9BQ52] synonym: "RNase Z 2" EXACT [UniProtKB:Q9BQ52] synonym: "tRNA 3 endonuclease 2" EXACT [UniProtKB:Q9BQ52] synonym: "tRNase Z 2" EXACT [UniProtKB:Q9BQ52] xref: EMBL:AAG24440.1 xref: EMBL:AAG24441.1 xref: EMBL:AAH01939.1 xref: EMBL:AAH04158.1 xref: EMBL:BAA91666.1 xref: EMBL:BAC85964.1 xref: EMBL:BAC86026.1 xref: EMBL:CAG33542.1 xref: UniProtKB:Q6IA94 xref: UniProtKB:Q9BQ52 xref: UniProtKB:Q9HAS8 xref: UniProtKB:Q9HAS9 xref: UniProtKB:Q9NVT1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022595 ! ELAC2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020244 ! ascc2-elac2 physical interaction relationship: participates_in CCO:I0020279 ! cutl1-elac2 physical interaction relationship: transforms_into CCO:B0070118 ! RNZ2_HUMAN-Phosphoserine199 relationship: transforms_into CCO:B0070119 ! RNZ2_HUMAN-Phosphoserine208 [Term] id: CCO:B0063442 name: TUTLA_HUMAN def: "Protein turtle homolog A precursor" [UniProtKB:Q9P2J2] synonym: "Immunoglobulin superfamily member 9A" EXACT [UniProtKB:Q9P2J2] xref: EMBL:BAA92593.1 xref: UniProtKB:Q9P2J2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022749 ! IGSF9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: participates_in CCO:I0020247 ! ascc2-igsf9 physical interaction [Term] id: CCO:B0063443 name: LIPL_HUMAN def: "Lipoprotein lipase precursor" [UniProtKB:P06858] synonym: "EC 3.1.1.34" EXACT [UniProtKB:P06858] synonym: "LPL" EXACT [UniProtKB:P06858] xref: EMBL:AAA59528.1 xref: EMBL:AAB20999.1 xref: EMBL:AAB21000.1 xref: EMBL:AAB59536.1 xref: EMBL:AAH11353.1 xref: EMBL:AAP35372.1 xref: EMBL:CAA32564.1 xref: EMBL:CAA38372.1 xref: EMBL:CAA48230.1 xref: UniProtKB:P06858 xref: UniProtKB:Q16282 xref: UniProtKB:Q16283 xref: UniProtKB:Q96FC4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022372 ! LPL_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000865 ! lipoprotein lipase activity relationship: has_function CCO:F0000999 ! phospholipase activity relationship: has_function CCO:F0001164 ! triacylglycerol lipase activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0001672 ! chylomicron relationship: participates_in CCO:I0020248 ! ascc2-lpl physical interaction [Term] id: CCO:B0063444 name: ATIF1_HUMAN def: "ATPase inhibitor, mitochondrial precursor" [UniProtKB:Q9UII2] xref: EMBL:AAF97495.1 xref: EMBL:AAH09677.1 xref: EMBL:BAA88422.1 xref: UniProtKB:Q9UII2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0021034 ! ATPIF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020254 ! atpif1-chd3 physical interaction [Term] id: CCO:B0063445 name: BLMH_HUMAN def: "Bleomycin hydrolase" [UniProtKB:Q13867] synonym: "BH" EXACT [UniProtKB:Q13867] synonym: "BLM hydrolase" EXACT [UniProtKB:Q13867] synonym: "BMH" EXACT [UniProtKB:Q13867] synonym: "EC 3.4.22.40" EXACT [UniProtKB:Q13867] xref: EMBL:AAC72951.1 xref: EMBL:AAH03616.1 xref: EMBL:AAP35664.1 xref: EMBL:BAD97123.1 xref: EMBL:CAA63078.1 xref: UniProtKB:Q13867 xref: UniProtKB:Q53F86 xref: UniProtKB:Q9UER9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022072 ! BLMH_human relationship: has_function CCO:F0000646 ! aminopeptidase activity relationship: has_function CCO:F0000649 ! carboxypeptidase activity relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001890 ! bleomycin hydrolase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020257 ! blmh-trio physical interaction [Term] id: CCO:B0063446 name: CK001_HUMAN def: "Uncharacterized protein C11orf1" [UniProtKB:Q9H5F2] xref: EMBL:AAH20628.1 xref: EMBL:BAB15674.1 xref: EMBL:CAB96538.1 xref: UniProtKB:Q9H5F2 xref: UniProtKB:Q9NQC6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022127 ! C11orf1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020258 ! c11orf1-setdb1 physical interaction [Term] id: CCO:B0063447 name: CI025_HUMAN def: "Uncharacterized protein C9orf25" [UniProtKB:Q8IW50] xref: EMBL:AAH25348.1 xref: EMBL:AAH41009.1 xref: EMBL:BAG53270.1 xref: EMBL:CAI13147.1 xref: EMBL:CAI13149.1 xref: EMBL:CAI13151.1 xref: EMBL:CAI13152.1 xref: EMBL:CAI13153.1 xref: EMBL:CAI15969.1 xref: EMBL:CAI15970.1 xref: EMBL:CAI15972.1 xref: EMBL:CAI15973.1 xref: EMBL:CAI15974.1 xref: EMBL:CAM16095.1 xref: EMBL:CAM22385.1 xref: EMBL:EAW58454.1 xref: UniProtKB:A2A364 xref: UniProtKB:Q5T590 xref: UniProtKB:Q5T591 xref: UniProtKB:Q5T592 xref: UniProtKB:Q5T594 xref: UniProtKB:Q5T595 xref: UniProtKB:Q8IW50 xref: UniProtKB:Q8TAZ8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022123 ! C9orf25_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020263 ! c9orf25-pola2 physical interaction relationship: transforms_into CCO:B0065857 ! CI025_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0065858 ! CI025_HUMAN-Phosphothreonine113 relationship: transforms_into CCO:B0065859 ! CI025_HUMAN-Phosphoserine115 [Term] id: CCO:B0063448 name: STAR9_HUMAN def: "StAR-related lipid transfer protein 9" [UniProtKB:Q9P2P6] synonym: "StARD9" EXACT [UniProtKB:Q9P2P6] synonym: "START domain-containing protein 9" EXACT [UniProtKB:Q9P2P6] xref: EMBL:BAA92538.1 xref: EMBL:BAC85502.1 xref: EMBL:CAB63725.1 xref: EMBL:CAH10513.1 xref: EMBL:CAH18258.1 xref: UniProtKB:Q68DG2 xref: UniProtKB:Q6AI01 xref: UniProtKB:Q6ZWK0 xref: UniProtKB:Q9P2P6 xref: UniProtKB:Q9UF70 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022681 ! STARD9_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: participates_in CCO:I0020272 ! cdk5rap2-stard9 physical interaction [Term] id: CCO:B0063449 name: STT3A_HUMAN def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A" [UniProtKB:P46977] synonym: "B5" EXACT [UniProtKB:P46977] synonym: "EC 2.4.1.119" EXACT [UniProtKB:P46977] synonym: "Integral membrane protein 1" EXACT [UniProtKB:P46977] synonym: "Oligosaccharyl transferase subunit STT3A" EXACT [UniProtKB:P46977] synonym: "STT3-A" EXACT [UniProtKB:P46977] synonym: "Transmembrane protein TMC" EXACT [UniProtKB:P46977] xref: EMBL:AAB05994.1 xref: EMBL:AAH20965.1 xref: EMBL:AAH48348.2 xref: EMBL:AAL77539.1 xref: EMBL:AAP35764.1 xref: EMBL:BAF82729.1 xref: EMBL:BAF83346.1 xref: EMBL:EAW67647.1 xref: UniProtKB:P46977 xref: UniProtKB:Q86XU9 xref: UniProtKB:Q8TE35 xref: UniProtKB:Q8WUB4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022682 ! STT3A_human relationship: has_function CCO:F0000959 ! oligosaccharyl transferase activity relationship: has_function CCO:F0000962 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000535 ! oligosaccharyl transferase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020281 ! csde1-itm1 physical interaction [Term] id: CCO:B0063450 name: DHX34_HUMAN def: "Probable ATP-dependent RNA helicase DHX34" [UniProtKB:Q14147] synonym: "DEAH box protein 34" EXACT [UniProtKB:Q14147] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q14147] xref: EMBL:BAA09483.2 xref: UniProtKB:Q14147 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022187 ! DHX34_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020291 ! dhx34-pola2 physical interaction [Term] id: CCO:B0063451 name: Q9H0E4_HUMAN def: "Putative uncharacterized protein DKFZp434D1428" [UniProtKB:Q9H0E4] xref: EMBL:CAB66764.1 xref: UniProtKB:Q9H0E4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022860 ! DKFZp434D1428_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020292 ! dkfzp434d1428-chd3 physical interaction [Term] id: CCO:B0063452 name: DPYL4_HUMAN def: "Dihydropyrimidinase-related protein 4" [UniProtKB:O14531] synonym: "Collapsin response mediator protein 3" EXACT [UniProtKB:O14531] synonym: "CRMP-3" EXACT [UniProtKB:O14531] synonym: "DRP-4" EXACT [UniProtKB:O14531] synonym: "ULIP4 protein" EXACT [UniProtKB:O14531] synonym: "UNC33-like phosphoprotein 4" EXACT [UniProtKB:O14531] xref: EMBL:BAA21886.1 xref: EMBL:CAA71872.1 xref: EMBL:CAI12185.1 xref: UniProtKB:O00240 xref: UniProtKB:O14531 xref: UniProtKB:Q5T0Q7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022197 ! DPYSL4_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020296 ! dpysl4-sh3gl3 physical interaction relationship: transforms_into CCO:B0065959 ! DPYL4_HUMAN-Phosphoserine544 [Term] id: CCO:B0063453 name: DRG1_HUMAN def: "Developmentally-regulated GTP-binding protein 1" [UniProtKB:Q9Y295] synonym: "DRG-1" EXACT [UniProtKB:Q9Y295] synonym: "NEDD-3" EXACT [UniProtKB:Q9Y295] synonym: "Neural precursor cell expressed developmentally down-regulated protein 3" EXACT [UniProtKB:Q9Y295] xref: EMBL:AAD12240.1 xref: EMBL:AAH19285.1 xref: EMBL:AAH20803.1 xref: EMBL:AAP35901.1 xref: EMBL:CAA06775.1 xref: EMBL:CAG30374.1 xref: EMBL:CAG46856.1 xref: EMBL:CAH71744.1 xref: EMBL:CAI12876.1 xref: UniProtKB:Q6FGP8 xref: UniProtKB:Q8WW69 xref: UniProtKB:Q9UGF2 xref: UniProtKB:Q9Y295 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022198 ! DRG1_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020297 ! drg1-capns1 physical interaction [Term] id: CCO:B0063454 name: CD48_HUMAN def: "CD48 antigen precursor" [UniProtKB:P09326] synonym: "B-lymphocyte activation marker BLAST-1" EXACT [UniProtKB:P09326] synonym: "BCM1 surface antigen" EXACT [UniProtKB:P09326] synonym: "CD48 antigen" EXACT [UniProtKB:P09326] synonym: "Leukocyte antigen MEM-102" EXACT [UniProtKB:P09326] synonym: "TCT.1" EXACT [UniProtKB:P09326] xref: EMBL:AAA35602.1 xref: EMBL:AAA36211.1 xref: EMBL:AAA62834.1 xref: EMBL:AAH16182.1 xref: EMBL:CAA29647.1 xref: EMBL:CAC00578.1 xref: UniProtKB:P09326 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022109 ! CD48_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: participates_in CCO:I0020298 ! eef1d-cd48 physical interaction [Term] id: CCO:B0063455 name: EPCR_HUMAN def: "Endothelial protein C receptor precursor" [UniProtKB:Q9UNN8] synonym: "Activated protein C receptor" EXACT [UniProtKB:Q9UNN8] synonym: "APC receptor" EXACT [UniProtKB:Q9UNN8] synonym: "CD201 antigen" EXACT [UniProtKB:Q9UNN8] synonym: "Endothelial cell protein C receptor" EXACT [UniProtKB:Q9UNN8] xref: EMBL:AAA63647.1 xref: EMBL:AAD43967.1 xref: EMBL:AAH14451.1 xref: EMBL:AAK53045.1 xref: EMBL:BAA77249.2 xref: EMBL:CAA61450.1 xref: EMBL:CAC16283.1 xref: EMBL:CAG33229.1 xref: UniProtKB:Q14218 xref: UniProtKB:Q6IB56 xref: UniProtKB:Q96CB3 xref: UniProtKB:Q9ULX1 xref: UniProtKB:Q9UNN8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022221 ! PROCR_human relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020304 ! epb49-procr physical interaction [Term] id: CCO:B0063456 name: FA10_HUMAN def: "Coagulation factor X precursor" [UniProtKB:P00742] synonym: "EC 3.4.21.6" EXACT [UniProtKB:P00742] synonym: "Stuart factor" EXACT [UniProtKB:P00742] synonym: "Stuart-Prower factor" EXACT [UniProtKB:P00742] xref: EMBL:AAA51984.1 xref: EMBL:AAA52421.1 xref: EMBL:AAA52486.1 xref: EMBL:AAA52490.1 xref: EMBL:AAA52636.1 xref: EMBL:AAA52764.1 xref: EMBL:AAH46125.1 xref: EMBL:AAM19347.1 xref: UniProtKB:P00742 xref: UniProtKB:Q14340 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022242 ! F10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020307 ! f10-prkab1 physical interaction relationship: participates_in CCO:I0020551 ! f10-mgst3 physical interaction relationship: transforms_into CCO:B0066062 ! FA10_HUMAN-4-carboxyglutamate46 relationship: transforms_into CCO:B0066063 ! FA10_HUMAN-4-carboxyglutamate47 relationship: transforms_into CCO:B0066064 ! FA10_HUMAN-4-carboxyglutamate54 relationship: transforms_into CCO:B0066065 ! FA10_HUMAN-4-carboxyglutamate56 relationship: transforms_into CCO:B0066066 ! FA10_HUMAN-4-carboxyglutamate59 relationship: transforms_into CCO:B0066067 ! FA10_HUMAN-4-carboxyglutamate60 relationship: transforms_into CCO:B0066068 ! FA10_HUMAN-4-carboxyglutamate65 relationship: transforms_into CCO:B0066069 ! FA10_HUMAN-4-carboxyglutamate66 relationship: transforms_into CCO:B0066070 ! FA10_HUMAN-4-carboxyglutamate69 relationship: transforms_into CCO:B0066071 ! FA10_HUMAN-4-carboxyglutamate72 relationship: transforms_into CCO:B0066072 ! FA10_HUMAN-4-carboxyglutamate79 relationship: transforms_into CCO:B0066073 ! FA10_HUMAN-3-hydroxyaspartate103 [Term] id: CCO:B0063457 name: CCD17_HUMAN def: "Coiled-coil domain-containing protein 17" [UniProtKB:Q96LX7] xref: EMBL:AAH29888.1 xref: EMBL:AAI28178.1 xref: EMBL:AAI28179.1 xref: EMBL:BAB71539.1 xref: EMBL:CAI22466.1 xref: UniProtKB:A1A4Y7 xref: UniProtKB:Q0P683 xref: UniProtKB:Q5T629 xref: UniProtKB:Q96LX7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022101 ! CCDC17_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020311 ! fgfr3-q96lx7 physical interaction [Term] id: CCO:B0063458 name: HBAZ_HUMAN def: "Hemoglobin subunit zeta" [UniProtKB:P02008] synonym: "HBAZ" EXACT [UniProtKB:P02008] synonym: "Hemoglobin zeta chain" EXACT [UniProtKB:P02008] synonym: "Zeta-globin" EXACT [UniProtKB:P02008] xref: EMBL:AAA61306.1 xref: EMBL:AAB59406.1 xref: EMBL:AAH27892.1 xref: EMBL:AAK61214.1 xref: EMBL:CAB06552.1 xref: UniProtKB:P02008 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022301 ! HBZ_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020312 ! fgfr3-hbz physical interaction relationship: transforms_into CCO:B0066757 ! HBAZ_HUMAN-N-acetylserine2 [Term] id: CCO:B0063459 name: GOLI_HUMAN def: "Goliath homolog precursor" [UniProtKB:Q86XS8] synonym: "RING finger protein 130" EXACT [UniProtKB:Q86XS8] xref: EMBL:AAF67007.1 xref: EMBL:AAH17100.2 xref: EMBL:AAH65244.1 xref: EMBL:AAH82267.1 xref: EMBL:AAI08307.1 xref: EMBL:AAM08686.1 xref: UniProtKB:Q32P32 xref: UniProtKB:Q641P9 xref: UniProtKB:Q6P177 xref: UniProtKB:Q7L2U2 xref: UniProtKB:Q86XS8 xref: UniProtKB:Q9P0J9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022284 ! RNF130_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020315 ! fgfr3-rnf130 physical interaction [Term] id: CCO:B0063460 name: P34_HUMAN def: "Alpha- and gamma-adaptin-binding protein p34" [UniProtKB:Q6PD74] xref: EMBL:AAH01975.1 xref: EMBL:AAH47026.1 xref: EMBL:AAH58886.1 xref: EMBL:BAB13845.1 xref: EMBL:CAB66649.1 xref: EMBL:CAG38571.1 xref: UniProtKB:Q6FI86 xref: UniProtKB:Q6PD74 xref: UniProtKB:Q7Z5X9 xref: UniProtKB:Q9H0P1 xref: UniProtKB:Q9HAK0 is_a: CCO:U0000007 ! cell cycle protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020316 ! p34-eif3s8 physical interaction relationship: transforms_into CCO:B0069021 ! P34_HUMAN-Phosphoserine310 relationship: transforms_into CCO:B0069022 ! P34_HUMAN-Phosphoserine311 [Term] id: CCO:B0063461 name: CB044_HUMAN def: "WD repeat-containing protein C2orf44" [UniProtKB:Q9H6R7] xref: EMBL:AAG17255.1 xref: EMBL:AAH35698.1 xref: EMBL:AAY24115.1 xref: EMBL:BAB15186.1 xref: EMBL:EAX00771.1 xref: UniProtKB:Q8IYK0 xref: UniProtKB:Q9H6R7 xref: UniProtKB:Q9HBP5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022090 ! C2orf44_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020317 ! flj21945-med31 physical interaction relationship: participates_in CCO:I0020641 ! rab35-flj21945 physical interaction relationship: transforms_into CCO:B0065828 ! CB044_HUMAN-Phosphoserine529 relationship: transforms_into CCO:B0065829 ! CB044_HUMAN-Phosphothreonine530 relationship: transforms_into CCO:B0065830 ! CB044_HUMAN-Phosphoserine690 [Term] id: CCO:B0063462 name: CO029_HUMAN def: "Uncharacterized protein C15orf29" [UniProtKB:Q9H079] xref: EMBL:AAH26234.1 xref: EMBL:AAI11001.1 xref: EMBL:BAB15394.1 xref: EMBL:CAB66842.1 xref: UniProtKB:Q2TAC0 xref: UniProtKB:Q9H079 xref: UniProtKB:Q9H670 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022142 ! C15orf29_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020318 ! c15orf29-myst2 physical interaction [Term] id: CCO:B0063463 name: FMNL_HUMAN def: "Formin-like protein 1" [UniProtKB:O95466] synonym: "CLL-associated antigen KW-13" EXACT [UniProtKB:O95466] synonym: "Leukocyte formin" EXACT [UniProtKB:O95466] xref: EMBL:AAH01710.2 xref: EMBL:AAH09000.2 xref: EMBL:AAH21906.1 xref: EMBL:AAH73988.1 xref: EMBL:AAL99920.1 xref: EMBL:AAP32476.1 xref: EMBL:CAA07870.1 xref: EMBL:CAG33040.1 xref: UniProtKB:O95466 xref: UniProtKB:Q6DKG5 xref: UniProtKB:Q6IBP3 xref: UniProtKB:Q86UH1 xref: UniProtKB:Q8N671 xref: UniProtKB:Q8TDH1 xref: UniProtKB:Q96H10 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022258 ! FMNL1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020319 ! fmnl1-g22p1 physical interaction relationship: transforms_into CCO:B0066218 ! FMNL_HUMAN-Phosphoserine184 relationship: transforms_into CCO:B0066219 ! FMNL_HUMAN-Phosphoserine624 [Term] id: CCO:B0063464 name: ABCF1_HUMAN def: "ATP-binding cassette sub-family F member 1" [UniProtKB:Q8NE71] synonym: "ATP-binding cassette 50" EXACT [UniProtKB:Q8NE71] synonym: "TNF-alpha-stimulated ABC protein" EXACT [UniProtKB:Q8NE71] xref: EMBL:AAC70891.1 xref: EMBL:AAH34488.1 xref: EMBL:BAB63325.1 xref: EMBL:BAC54928.1 xref: EMBL:CAH10648.1 xref: EMBL:CAI17836.1 xref: EMBL:CAI17837.1 xref: EMBL:CAI18158.1 xref: EMBL:CAI18159.1 xref: EMBL:CAI18562.1 xref: EMBL:CAI18563.1 xref: UniProtKB:O14897 xref: UniProtKB:Q69YP6 xref: UniProtKB:Q8NE71 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022020 ! ABCF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020345 ! itgb3bp-abcf1 physical interaction relationship: transforms_into CCO:B0065268 ! ABCF1_HUMAN-Phosphoserine24 relationship: transforms_into CCO:B0065269 ! ABCF1_HUMAN-Phosphoserine105 relationship: transforms_into CCO:B0065270 ! ABCF1_HUMAN-Phosphothreonine108 relationship: transforms_into CCO:B0065271 ! ABCF1_HUMAN-Phosphoserine109 relationship: transforms_into CCO:B0065272 ! ABCF1_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0065273 ! ABCF1_HUMAN-Phosphoserine166 relationship: transforms_into CCO:B0065274 ! ABCF1_HUMAN-Phosphoserine228 relationship: transforms_into CCO:B0065275 ! ABCF1_HUMAN-Phosphoserine595 [Term] id: CCO:B0063465 name: CD027_HUMAN def: "UPF0609 protein C4orf27" [UniProtKB:Q9NWY4] xref: EMBL:AAH10367.1 xref: EMBL:BAA91241.1 xref: EMBL:CAB66608.1 xref: UniProtKB:Q9NWY4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022106 ! C4orf27_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020347 ! itgb3bp-flj20534 physical interaction [Term] id: CCO:B0063466 name: RT31_HUMAN def: "28S ribosomal protein S31, mitochondrial precursor" [UniProtKB:Q92665] synonym: "Imogen 38" EXACT [UniProtKB:Q92665] synonym: "MRP-S31" EXACT [UniProtKB:Q92665] synonym: "S31mt" EXACT [UniProtKB:Q92665] xref: EMBL:AAH22045.1 xref: EMBL:CAA92951.1 xref: EMBL:CAH70977.1 xref: EMBL:CAH72771.1 xref: UniProtKB:Q5VYC8 xref: UniProtKB:Q8WTV8 xref: UniProtKB:Q92665 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022619 ! MRPS31_human relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0020348 ! itgb3bp-mrps31 physical interaction [Term] id: CCO:B0063467 name: OFD1_HUMAN def: "Oral-facial-digital syndrome 1 protein" [UniProtKB:O75665] synonym: "Protein 71-7A" EXACT [UniProtKB:O75665] xref: EMBL:AAH96344.1 xref: EMBL:CAA75436.1 xref: EMBL:CAA76185.1 xref: UniProtKB:O75665 xref: UniProtKB:O75666 xref: UniProtKB:Q4VAK4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022476 ! OFD1_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: participates_in CCO:I0020349 ! itgb3bp-ofd1 physical interaction [Term] id: CCO:B0063468 name: UBP33_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 33" [UniProtKB:Q8TEY7] synonym: "Deubiquitinating enzyme 33" EXACT [UniProtKB:Q8TEY7] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q8TEY7] synonym: "Ubiquitin thioesterase 33" EXACT [UniProtKB:Q8TEY7] synonym: "Ubiquitin-specific-processing protease 33" EXACT [UniProtKB:Q8TEY7] synonym: "VHL-interacting deubiquitinating enzyme 1" EXACT [UniProtKB:Q8TEY7] xref: EMBL:AAH16663.1 xref: EMBL:AAL78314.1 xref: EMBL:AAL78315.1 xref: EMBL:BAA83049.1 xref: EMBL:BAB14279.1 xref: UniProtKB:Q8TEY6 xref: UniProtKB:Q8TEY7 xref: UniProtKB:Q96AV6 xref: UniProtKB:Q9H9F0 xref: UniProtKB:Q9UPQ5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022763 ! USP33_human relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001069 ! VCB complex relationship: participates_in CCO:I0020350 ! itgb3bp-usp33 physical interaction relationship: transforms_into CCO:B0071698 ! UBP33_HUMAN-Phosphoserine439 [Term] id: CCO:B0063469 name: ODF2L_HUMAN def: "Outer dense fiber protein 2-like" [UniProtKB:Q9ULJ1] xref: EMBL:AAH29420.1 xref: EMBL:AAH47368.1 xref: EMBL:AAH91490.1 xref: EMBL:BAA86543.1 xref: EMBL:CAI23513.1 xref: EMBL:CAI23514.1 xref: EMBL:EAW73190.1 xref: EMBL:EAW73192.1 xref: UniProtKB:Q05C40 xref: UniProtKB:Q5BJG5 xref: UniProtKB:Q5TBX3 xref: UniProtKB:Q5TBX4 xref: UniProtKB:Q86X31 xref: UniProtKB:Q9ULJ1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022473 ! ODF2L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020354 ! kiaa1229-erbb3 physical interaction [Term] id: CCO:B0063470 name: BR44L_HUMAN def: "Brain protein 44-like protein" [UniProtKB:Q9Y5U8] xref: EMBL:AAD34124.1 xref: EMBL:AAD39918.1 xref: EMBL:AAG23822.1 xref: EMBL:AAH00810.1 xref: EMBL:CAI19654.1 xref: UniProtKB:Q5TI66 xref: UniProtKB:Q9HB67 xref: UniProtKB:Q9UQN4 xref: UniProtKB:Q9Y5U8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022074 ! BRP44L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020362 ! maged1-brp44l physical interaction relationship: transforms_into CCO:B0065799 ! BR44L_HUMAN-N-acetylalanine2 [Term] id: CCO:B0063471 name: TM216_HUMAN def: "Transmembrane protein 216" [UniProtKB:Q9P0N5] xref: EMBL:AAF36164.1 xref: EMBL:AAH11010.1 xref: EMBL:CAG33447.1 xref: UniProtKB:A8MZ23 xref: UniProtKB:Q9P0N5 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022718 ! TMEM216_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020367 ! mgc:13379-mcm3ap physical interaction [Term] id: CCO:B0063472 name: F101B_HUMAN def: "Protein FAM101B" [UniProtKB:Q8N5W9] xref: EMBL:AAH31341.1 xref: UniProtKB:Q8N5W9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022233 ! FAM101B_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020369 ! mgc45871-htatip physical interaction [Term] id: CCO:B0063473 name: CC137_HUMAN def: "Coiled-coil domain-containing protein 137" [UniProtKB:Q6PK04] xref: EMBL:AAH09369.1 xref: UniProtKB:Q6PK04 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022099 ! CCDC137_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020373 ! mpp3-mgc16597 physical interaction relationship: transforms_into CCO:B0065836 ! CC137_HUMAN-Phosphoserine19 relationship: transforms_into CCO:B0065837 ! CC137_HUMAN-Phosphoserine233 [Term] id: CCO:B0063474 name: RS2_HUMAN def: "40S ribosomal protein S2" [UniProtKB:P15880] synonym: "LLRep3 protein" EXACT [UniProtKB:P15880] synonym: "S4" EXACT [UniProtKB:P15880] xref: EMBL:AAH01795.1 xref: EMBL:AAH06559.1 xref: EMBL:AAH08862.1 xref: EMBL:AAH10165.1 xref: EMBL:AAH12354.1 xref: EMBL:AAH16178.1 xref: EMBL:AAH16951.1 xref: EMBL:AAH18993.1 xref: EMBL:AAH21545.1 xref: EMBL:AAH23541.1 xref: EMBL:AAH25677.1 xref: EMBL:AAH66321.1 xref: EMBL:AAH68051.1 xref: EMBL:AAH71922.1 xref: EMBL:AAH71923.1 xref: EMBL:AAH71924.1 xref: EMBL:AAH73966.1 xref: EMBL:AAH75830.1 xref: EMBL:AAI03757.1 xref: EMBL:AAI05986.1 xref: EMBL:CAA35078.1 xref: UniProtKB:P15880 xref: UniProtKB:Q3MIB1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022614 ! RPS2_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: participates_in CCO:I0020374 ! mpp3-rps2 physical interaction relationship: transforms_into CCO:B0070203 ! RS2_HUMAN-Phosphoserine77 relationship: transforms_into CCO:B0070204 ! RS2_HUMAN-Phosphotyrosine82 relationship: transforms_into CCO:B0070205 ! RS2_HUMAN-Phosphoserine85 relationship: transforms_into CCO:B0070206 ! RS2_HUMAN-Phosphotyrosine133 relationship: transforms_into CCO:B0070207 ! RS2_HUMAN-Phosphoserine264 relationship: transforms_into CCO:B0070208 ! RS2_HUMAN-Phosphothreonine278 relationship: transforms_into CCO:B0070209 ! RS2_HUMAN-Phosphoserine281 relationship: transforms_into CCO:B0070210 ! RS2_HUMAN-Phosphothreonine293 [Term] id: CCO:B0063475 name: HMGCL_HUMAN def: "Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor" [UniProtKB:P35914] synonym: "3-hydroxy-3-methylglutarate-CoA lyase" EXACT [UniProtKB:P35914] synonym: "EC 4.1.3.4" EXACT [UniProtKB:P35914] synonym: "HL" EXACT [UniProtKB:P35914] synonym: "HMG-CoA lyase" EXACT [UniProtKB:P35914] xref: EMBL:AAA92733.1 xref: EMBL:AAB19099.1 xref: EMBL:AAH10570.1 xref: UniProtKB:P35914 xref: UniProtKB:Q96FP8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022307 ! HMGCL_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020375 ! ms4a7-hmgcl physical interaction relationship: transforms_into CCO:B0066831 ! HMGCL_HUMAN-N6-acetyllysine48 [Term] id: CCO:B0063476 name: PTHD2_HUMAN def: "Patched domain-containing protein 2" [UniProtKB:Q9P2K9] synonym: "Protein dispatched homolog 3" EXACT [UniProtKB:Q9P2K9] xref: EMBL:BAA92575.1 xref: EMBL:CAB55303.1 xref: EMBL:CAH70606.1 xref: EMBL:CAI22474.1 xref: UniProtKB:Q5VTU9 xref: UniProtKB:Q9P2K9 xref: UniProtKB:Q9UJD6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022539 ! PTCHD2_human relationship: has_function CCO:F0001752 ! hedgehog receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020378 ! mycbp-kiaa1337 physical interaction [Term] id: CCO:B0063477 name: NDUA7_HUMAN def: "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7" [UniProtKB:O95182] synonym: "CI-B14.5a" EXACT [UniProtKB:O95182] synonym: "Complex I-B14.5a" EXACT [UniProtKB:O95182] synonym: "NADH-ubiquinone oxidoreductase subunit B14.5a" EXACT [UniProtKB:O95182] xref: EMBL:AAC99399.1 xref: EMBL:AAD05427.1 xref: EMBL:AAH03102.1 xref: UniProtKB:O95182 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022436 ! NDUFA7_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020381 ! ndufa7-prkab1 physical interaction relationship: transforms_into CCO:B0068548 ! NDUA7_HUMAN-N-acetylalanine2 relationship: transforms_into CCO:B0068549 ! NDUA7_HUMAN-Phosphoserine63 [Term] id: CCO:B0063478 name: FXYD3_HUMAN def: "FXYD domain-containing ion transport regulator 3 precursor" [UniProtKB:Q14802] synonym: "Chloride conductance inducer protein Mat-8" EXACT [UniProtKB:Q14802] synonym: "Mammary tumor 8 kDa protein" EXACT [UniProtKB:Q14802] synonym: "Phospholemman-like" EXACT [UniProtKB:Q14802] xref: EMBL:AAA73922.1 xref: EMBL:AAH05238.1 xref: EMBL:AAH90044.1 xref: EMBL:AAP35358.1 xref: EMBL:CAA63604.1 xref: EMBL:CAG33226.1 xref: EMBL:CAG46994.1 xref: UniProtKB:A6NDE0 xref: UniProtKB:Q13211 xref: UniProtKB:Q14802 xref: UniProtKB:Q6IB59 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022265 ! FXYD3_human relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020385 ! nr4a1-fxyd3 physical interaction [Term] id: CCO:B0063479 name: NUDT5_HUMAN def: "ADP-sugar pyrophosphatase" [UniProtKB:Q9UKK9] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9UKK9] synonym: "EC 3.6.1.13" EXACT [UniProtKB:Q9UKK9] synonym: "Nucleoside diphosphate-linked moiety X motif 5" EXACT [UniProtKB:Q9UKK9] synonym: "Nudix motif 5" EXACT [UniProtKB:Q9UKK9] synonym: "YSA1H" EXACT [UniProtKB:Q9UKK9] xref: EMBL:AAF06734.1 xref: EMBL:AAF25479.1 xref: EMBL:AAF29079.1 xref: EMBL:AAH00025.1 xref: EMBL:CAG33476.1 xref: UniProtKB:Q6IAG0 xref: UniProtKB:Q9UH49 xref: UniProtKB:Q9UKK9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022464 ! NUDT5_human relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004079 ! ADP-sugar diphosphatase activity relationship: has_function CCO:F0006933 ! ADP-ribose diphosphatase activity relationship: has_function CCO:F0008047 ! ADP reductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: participates_in CCO:I0020389 ! nudt5-mcm3ap physical interaction relationship: transforms_into CCO:B0068908 ! NUDT5_HUMAN-Phosphoserine9 relationship: transforms_into CCO:B0068909 ! NUDT5_HUMAN-Phosphotyrosine74 [Term] id: CCO:B0063480 name: PACN1_HUMAN def: "Protein kinase C and casein kinase substrate in neurons protein 1" [UniProtKB:Q9BY11] xref: EMBL:AAH40228.1 xref: EMBL:AAK29206.1 xref: EMBL:BAA92617.2 xref: EMBL:CAD38895.1 xref: UniProtKB:Q9BY11 xref: UniProtKB:Q9P2G8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022489 ! PACSIN1_human relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020392 ! pacsin1-myst2 physical interaction relationship: transforms_into CCO:B0069044 ! PACN1_HUMAN-Phosphotyrosine394 [Term] id: CCO:B0063481 name: PIGC_HUMAN def: "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C" [UniProtKB:Q92535] synonym: "EC 2.4.1.198" EXACT [UniProtKB:Q92535] synonym: "Phosphatidylinositol-glycan biosynthesis class C protein" EXACT [UniProtKB:Q92535] synonym: "PIG-C" EXACT [UniProtKB:Q92535] xref: EMBL:AAH06539.1 xref: EMBL:AAP35380.1 xref: EMBL:BAA12812.1 xref: EMBL:BAA22866.1 xref: EMBL:CAB10071.1 xref: EMBL:CAG29288.1 xref: UniProtKB:O14491 xref: UniProtKB:Q92535 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022513 ! PIGC_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0003613 ! phosphatidylinositol N-acetylglucosaminyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020404 ! pigc-zhx1 physical interaction [Term] id: CCO:B0063482 name: WDR89_HUMAN def: "WD repeat-containing protein 89" [UniProtKB:Q96FK6] xref: EMBL:AAH10698.1 xref: EMBL:AAO06950.1 xref: EMBL:BAC04530.1 xref: EMBL:CAD62336.1 xref: UniProtKB:Q96FK6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022785 ! WDR89_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020405 ! polr3f-c14orf150 physical interaction relationship: transforms_into CCO:B0071840 ! WDR89_HUMAN-Phosphoserine67 relationship: transforms_into CCO:B0071841 ! WDR89_HUMAN-Phosphotyrosine69 [Term] id: CCO:B0063483 name: CBR3_HUMAN def: "Carbonyl reductase [NADPH] 3" [UniProtKB:O75828] synonym: "EC 1.1.1.184" EXACT [UniProtKB:O75828] synonym: "NADPH-dependent carbonyl reductase 3" EXACT [UniProtKB:O75828] xref: EMBL:AAH02812.1 xref: EMBL:BAA33500.1 xref: EMBL:BAA34207.1 xref: EMBL:BAA89425.1 xref: EMBL:BAA95547.1 xref: UniProtKB:O75828 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022093 ! CBR3_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000565 ! carbonyl reductase (NADPH) activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020427 ! rab35-cbr3 physical interaction [Term] id: CCO:B0063484 name: RN146_HUMAN def: "RING finger protein 146" [UniProtKB:Q9NTX7] synonym: "Dactylidin" EXACT [UniProtKB:Q9NTX7] xref: EMBL:AAH08235.1 xref: EMBL:BAB55196.1 xref: EMBL:BAB55359.1 xref: EMBL:CAB66763.1 xref: EMBL:CAB76254.1 xref: EMBL:CAB76255.1 xref: EMBL:CAC85986.1 xref: EMBL:CAG38545.1 xref: UniProtKB:Q6FIB2 xref: UniProtKB:Q7L8H4 xref: UniProtKB:Q96K03 xref: UniProtKB:Q9NTX6 xref: UniProtKB:Q9NTX7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022590 ! RNF146_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020438 ! rnf146-pfn2 physical interaction [Term] id: CCO:B0063485 name: S38A3_HUMAN def: "Sodium-coupled neutral amino acid transporter 3" [UniProtKB:Q99624] synonym: "N-system amino acid transporter 1" EXACT [UniProtKB:Q99624] synonym: "Na(+)-coupled neutral amino acid transporter 3" EXACT [UniProtKB:Q99624] synonym: "Solute carrier family 38 member 3" EXACT [UniProtKB:Q99624] synonym: "System N amino acid transporter 1" EXACT [UniProtKB:Q99624] xref: EMBL:AAB47236.1 xref: EMBL:AAG15313.1 xref: EMBL:AAH42875.1 xref: EMBL:CAD97624.1 xref: EMBL:CAG33251.1 xref: UniProtKB:Q6IB34 xref: UniProtKB:Q99624 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022632 ! SLC38A3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020453 ! slc38a3-setdb1 physical interaction relationship: transforms_into CCO:B0070286 ! S38A3_HUMAN-Phosphoserine52 relationship: transforms_into CCO:B0070287 ! S38A3_HUMAN-Phosphoserine54 [Term] id: CCO:B0063486 name: PRRT2_HUMAN def: "Proline-rich transmembrane protein 2" [UniProtKB:Q7Z6L0] xref: EMBL:AAH11405.1 xref: EMBL:AAH53594.1 xref: EMBL:BAC03843.1 xref: EMBL:BAC11067.1 xref: EMBL:CAD38881.1 xref: UniProtKB:Q7Z6L0 xref: UniProtKB:Q8N2N8 xref: UniProtKB:Q8NAQ7 xref: UniProtKB:Q8ND36 xref: UniProtKB:Q96FA8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022536 ! PRRT2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020455 ! snap25-loc112476 physical interaction [Term] id: CCO:B0063487 name: Q5JU30_HUMAN def: "SH2 domain containing 3C" [UniProtKB:Q5JU30] xref: EMBL:CAI39762.1 xref: EMBL:CAI41178.1 xref: UniProtKB:Q5JU30 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0019889 ! SH2D3C_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020458 ! sncaip-sh2d3c physical interaction [Term] id: CCO:B0063488 name: KAD5_HUMAN def: "Adenylate kinase isoenzyme 5" [UniProtKB:Q9Y6K8] synonym: "AK 5" EXACT [UniProtKB:Q9Y6K8] synonym: "ATP-AMP transphosphorylase 5" EXACT [UniProtKB:Q9Y6K8] synonym: "EC 2.7.4.3" EXACT [UniProtKB:Q9Y6K8] xref: EMBL:AAD27956.1 xref: EMBL:AAH12467.2 xref: UniProtKB:Q96EC9 xref: UniProtKB:Q9Y6K8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022346 ! AK5_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020461 ! strn4-ak5 physical interaction [Term] id: CCO:B0063489 name: CLD12_HUMAN def: "Claudin-12" [UniProtKB:P56749] xref: EMBL:AAH36754.1 xref: EMBL:AAH68532.1 xref: EMBL:CAB60617.1 xref: EMBL:CAB66704.1 xref: UniProtKB:P56749 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022137 ! CLDN12_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020463 ! strn4-cldn12 physical interaction relationship: transforms_into CCO:B0065880 ! CLD12_HUMAN-Phosphoserine228 [Term] id: CCO:B0063490 name: NBEA_HUMAN def: "Neurobeachin" [UniProtKB:Q8NFP9] synonym: "Lysosomal-trafficking regulator 2" EXACT [UniProtKB:Q8NFP9] synonym: "Protein BCL8B" EXACT [UniProtKB:Q8NFP9] xref: EMBL:AAD41633.1 xref: EMBL:AAM53531.1 xref: EMBL:BAA91485.1 xref: EMBL:BAB13370.1 xref: EMBL:CAB70903.2 xref: UniProtKB:Q8NFP9 xref: UniProtKB:Q9HCM8 xref: UniProtKB:Q9NSU1 xref: UniProtKB:Q9NW98 xref: UniProtKB:Q9Y6J1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022427 ! NBEA_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020465 ! strn4-nbea physical interaction relationship: transforms_into CCO:B0068447 ! NBEA_HUMAN-Phosphoserine1529 [Term] id: CCO:B0063491 name: SPRN_HUMAN def: "Shadow of prion protein precursor" [UniProtKB:Q5BIV9] synonym: "Protein shadoo" EXACT [UniProtKB:Q5BIV9] xref: EMBL:AAH40198.1 xref: EMBL:CAG34288.1 xref: UniProtKB:Q5BIV9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022670 ! SPRN_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0020468 ! strn4-sprn physical interaction [Term] id: CCO:B0063492 name: Q8IZ48_HUMAN def: "Fas-binding factor 1." [UniProtKB:Q8IZ48] xref: EMBL:AAH23549.1 xref: UniProtKB:Q8IZ48 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022845 ! FBF1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020471 ! tcea2-fbf1 physical interaction [Term] id: CCO:B0063493 name: PYR5_HUMAN def: "Uridine 5'-monophosphate synthase" [UniProtKB:P11172] synonym: "UMP synthase" EXACT [UniProtKB:P11172] xref: EMBL:AAA61255.1 xref: EMBL:AAA61256.1 xref: EMBL:AAH00364.1 xref: EMBL:AAH07511.1 xref: EMBL:AAT85801.1 xref: EMBL:BAA19920.1 xref: EMBL:BAA19921.1 xref: EMBL:BAA19923.1 xref: EMBL:BAB20663.1 xref: EMBL:BAB93468.1 xref: EMBL:CAB45710.3 xref: EMBL:CAG33068.1 xref: UniProtKB:O00758 xref: UniProtKB:O00759 xref: UniProtKB:O00760 xref: UniProtKB:P11172 xref: UniProtKB:Q16862 xref: UniProtKB:Q9H3Q2 xref: UniProtKB:Q9UG49 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022548 ! UMPS_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000970 ! orotate phosphoribosyltransferase activity relationship: has_function CCO:F0000972 ! orotidine-5'-phosphate decarboxylase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003398 ! carboxy-lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: participates_in CCO:I0020493 ! umps-cdc42ep3 physical interaction relationship: transforms_into CCO:B0069653 ! PYR5_HUMAN-Phosphotyrosine37 [Term] id: CCO:B0063494 name: UBP13_HUMAN def: "Ubiquitin carboxyl-terminal hydrolase 13" [UniProtKB:Q92995] synonym: "Deubiquitinating enzyme 13" EXACT [UniProtKB:Q92995] synonym: "EC 3.1.2.15" EXACT [UniProtKB:Q92995] synonym: "Isopeptidase T-3" EXACT [UniProtKB:Q92995] synonym: "ISOT-3" EXACT [UniProtKB:Q92995] synonym: "Ubiquitin thioesterase 13" EXACT [UniProtKB:Q92995] synonym: "Ubiquitin-specific-processing protease 13" EXACT [UniProtKB:Q92995] xref: EMBL:AAC63405.1 xref: EMBL:AAH16146.1 xref: EMBL:EAW78383.1 xref: UniProtKB:Q92995 xref: UniProtKB:Q96B25 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022759 ! USP13_human relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020495 ! usp13-dvl1 physical interaction relationship: transforms_into CCO:B0071677 ! UBP13_HUMAN-Phosphothreonine122 [Term] id: CCO:B0063495 name: S2538_HUMAN def: "Solute carrier family 25 member 38" [UniProtKB:Q96DW6] xref: EMBL:AAH13194.1 xref: EMBL:BAA91253.1 xref: EMBL:CAG33523.1 xref: UniProtKB:Q96DW6 xref: UniProtKB:Q9NWX2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022630 ! SLC25A38_human relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020499 ! znf435-flj20551 physical interaction [Term] id: CCO:B0063496 name: ACTY_HUMAN def: "Beta-centractin" [UniProtKB:P42025] synonym: "Actin-related protein 1B" EXACT [UniProtKB:P42025] synonym: "ARP1B" EXACT [UniProtKB:P42025] xref: EMBL:AAH04374.1 xref: EMBL:AAH06372.1 xref: EMBL:AAH10090.1 xref: EMBL:AAY24280.1 xref: EMBL:CAA57691.1 xref: UniProtKB:P42025 xref: UniProtKB:Q53SK5 xref: UniProtKB:Q9BRB7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022024 ! ACTR1B_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000429 ! dynactin complex relationship: participates_in CCO:I0020501 ! actr1b-chd3 physical interaction [Term] id: CCO:B0063497 name: Q6IBE6_HUMAN def: "SIAT4C protein" [UniProtKB:Q6IBE6] synonym: "cDNA, FLJ95600, Homo sapiens sialyltransferase 4C (beta-galactosidealpha-2,3-sialyltransferase) (SIAT4C), mRNA" EXACT [UniProtKB:Q6IBE6] synonym: "ST3 beta-galactoside alpha-2,3-sialyltransferase 4, isoform CRA_c" EXACT [UniProtKB:Q6IBE6] xref: EMBL:BAG37279.1 xref: EMBL:CAG33139.1 xref: EMBL:EAW67695.1 xref: UniProtKB:Q6IBE6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022836 ! SIAT4C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020508 ! arhgdia-siat4c physical interaction [Term] id: CCO:B0063498 name: NDUS7_HUMAN def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial precursor" [UniProtKB:O75251] synonym: "CI-20kD" EXACT [UniProtKB:O75251] synonym: "Complex I-20kD" EXACT [UniProtKB:O75251] synonym: "EC 1.6.5.3" EXACT [UniProtKB:O75251] synonym: "EC 1.6.99.3" EXACT [UniProtKB:O75251] synonym: "NADH-ubiquinone oxidoreductase 20 kDa subunit" EXACT [UniProtKB:O75251] synonym: "PSST subunit" EXACT [UniProtKB:O75251] xref: EMBL:AAC27669.1 xref: EMBL:AAH01715.2 xref: EMBL:AAH05954.1 xref: EMBL:AAI11518.1 xref: UniProtKB:O75251 xref: UniProtKB:Q2T9H7 xref: UniProtKB:Q9BV17 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022440 ! NDUFS7_human relationship: has_function CCO:F0000447 ! NADH dehydrogenase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH relationship: has_function CCO:F0003253 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008141 ! 4 iron, 4 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: participates_in CCO:I0020514 ! arrb2-ndufs7 physical interaction [Term] id: CCO:B0063499 name: HN1L_HUMAN def: "Hematological and neurological expressed 1-like protein" [UniProtKB:Q9H910] synonym: "HN1-like protein" EXACT [UniProtKB:Q9H910] xref: EMBL:AAH14438.1 xref: EMBL:AAH60853.1 xref: EMBL:AAK61289.1 xref: EMBL:AAP72616.1 xref: EMBL:AAP83791.1 xref: EMBL:AAP83792.1 xref: EMBL:AAT06741.1 xref: EMBL:BAB14434.1 xref: UniProtKB:Q6EIC7 xref: UniProtKB:Q9H910 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022308 ! HN1L_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020518 ! c16orf34-g22p1 physical interaction relationship: participates_in CCO:I0020647 ! rasa4-c16orf34 physical interaction relationship: participates_in CCO:I0020665 ! slc25a20-c16orf34 physical interaction relationship: transforms_into CCO:B0066840 ! HN1L_HUMAN-Phosphoserine25 relationship: transforms_into CCO:B0066841 ! HN1L_HUMAN-Phosphoserine30 relationship: transforms_into CCO:B0066842 ! HN1L_HUMAN-Phosphothreonine35 relationship: transforms_into CCO:B0066843 ! HN1L_HUMAN-Phosphoserine75 relationship: transforms_into CCO:B0066844 ! HN1L_HUMAN-Phosphothreonine76 relationship: transforms_into CCO:B0066845 ! HN1L_HUMAN-Phosphoserine97 relationship: transforms_into CCO:B0066846 ! HN1L_HUMAN-Phosphoserine125 relationship: transforms_into CCO:B0066847 ! HN1L_HUMAN-Phosphoserine132 relationship: transforms_into CCO:B0066848 ! HN1L_HUMAN-Phosphoserine144 [Term] id: CCO:B0063500 name: Q53YB2_HUMAN def: "Putative receptor protein (Transmembrane protein 11, isoform CRA_a) (cDNA, FLJ92237)" [UniProtKB:Q53YB2] xref: EMBL:AAP35414.1 xref: EMBL:BAG34905.1 xref: EMBL:EAX02598.1 xref: UniProtKB:Q53YB2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0020290 ! TMEM11_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020519 ! q53yb2-scmh1 physical interaction [Term] id: CCO:B0063501 name: CCD50_HUMAN def: "Coiled-coil domain-containing protein 50" [UniProtKB:Q8IVM0] synonym: "Protein Ymer" EXACT [UniProtKB:Q8IVM0] xref: EMBL:AAH65004.1 xref: EMBL:CAC95196.1 xref: EMBL:CAD89526.1 xref: UniProtKB:Q86VH7 xref: UniProtKB:Q8IVM0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022102 ! CCDC50_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020522 ! c3orf6-rps3a physical interaction relationship: transforms_into CCO:B0065839 ! CCD50_HUMAN-Phosphotyrosine140 relationship: transforms_into CCO:B0065840 ! CCD50_HUMAN-Phosphotyrosine144 relationship: transforms_into CCO:B0065841 ! CCD50_HUMAN-Phosphotyrosine145 relationship: transforms_into CCO:B0065842 ! CCD50_HUMAN-Phosphotyrosine279 [Term] id: CCO:B0063502 name: Q9UJD7_HUMAN def: "Putative uncharacterized protein" [UniProtKB:Q9UJD7] synonym: "Patched domain containing 2" EXACT [UniProtKB:Q9UJD7] xref: EMBL:CAB55302.1 xref: EMBL:CAI22475.1 xref: UniProtKB:Q9UJD7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022539 ! PTCHD2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020525 ! rp1_69m21_1-mdfi physical interaction [Term] id: CCO:B0063503 name: QCR8_HUMAN def: "Cytochrome b-c1 complex subunit 8" [UniProtKB:O14949] synonym: "Complex III subunit 8" EXACT [UniProtKB:O14949] synonym: "Complex III subunit VIII" EXACT [UniProtKB:O14949] synonym: "Ubiquinol-cytochrome c reductase complex 9.5 kDa protein" EXACT [UniProtKB:O14949] synonym: "Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C" EXACT [UniProtKB:O14949] xref: EMBL:AAH01390.1 xref: EMBL:AAH90048.1 xref: EMBL:BAA23321.1 xref: UniProtKB:O14949 xref: UniProtKB:Q5FVE2 xref: UniProtKB:Q9BV88 xref: UniProtKB:Q9T2V7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022549 ! UQCRQ_human relationship: has_function CCO:F0001727 ! ubiquinol-cytochrome-c reductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000766 ! membrane relationship: participates_in CCO:I0020532 ! ercc8-qp_c physical interaction [Term] id: CCO:B0063504 name: CAH12_HUMAN def: "Carbonic anhydrase 12 precursor" [UniProtKB:O43570] synonym: "CA-XII" EXACT [UniProtKB:O43570] synonym: "Carbonate dehydratase XII" EXACT [UniProtKB:O43570] synonym: "Carbonic anhydrase XII" EXACT [UniProtKB:O43570] synonym: "EC 4.2.1.1" EXACT [UniProtKB:O43570] synonym: "HOM-RCC-3.1.3 tumor antigen" EXACT [UniProtKB:O43570] xref: EMBL:AAC39789.1 xref: EMBL:AAC63952.1 xref: EMBL:AAH00278.1 xref: EMBL:AAH11691.1 xref: EMBL:AAH23981.1 xref: EMBL:AAP35302.1 xref: UniProtKB:O43570 xref: UniProtKB:Q53YE5 xref: UniProtKB:Q9BWG2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022083 ! CA12_human relationship: has_function CCO:F0000564 ! carbonate dehydratase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020534 ! cutl1-ca12 physical interaction [Term] id: CCO:B0063505 name: DDX18_HUMAN def: "ATP-dependent RNA helicase DDX18" [UniProtKB:Q9NVP1] synonym: "DEAD box protein 18" EXACT [UniProtKB:Q9NVP1] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q9NVP1] synonym: "MrDb" EXACT [UniProtKB:Q9NVP1] synonym: "Myc-regulated DEAD box protein" EXACT [UniProtKB:Q9NVP1] xref: EMBL:AAH01238.1 xref: EMBL:AAH03360.1 xref: EMBL:AAH24739.1 xref: EMBL:BAA91709.1 xref: EMBL:CAA67295.1 xref: EMBL:CAG33341.1 xref: UniProtKB:Q6GTZ9 xref: UniProtKB:Q6IAU4 xref: UniProtKB:Q92732 xref: UniProtKB:Q9BQB7 xref: UniProtKB:Q9NVP1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022175 ! DDX18_human relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020537 ! ddx18-inadl physical interaction relationship: participates_in CCO:I0020538 ! ddx18-mta1 physical interaction [Term] id: CCO:B0063506 name: DHX29_HUMAN def: "Putative ATP-dependent RNA helicase DHX29" [UniProtKB:Q7Z478] synonym: "DEAH box protein 29" EXACT [UniProtKB:Q7Z478] synonym: "EC 3.6.1.-" EXACT [UniProtKB:Q7Z478] synonym: "Nucleic acid helicase DDXx" EXACT [UniProtKB:Q7Z478] xref: EMBL:AAC25394.1 xref: EMBL:AAH56219.1 xref: EMBL:AAK64516.1 xref: EMBL:CAB45191.1 xref: EMBL:CAD39154.1 xref: EMBL:CAH56153.1 xref: EMBL:CAH56172.1 xref: UniProtKB:O75549 xref: UniProtKB:Q63HN0 xref: UniProtKB:Q63HN3 xref: UniProtKB:Q7Z478 xref: UniProtKB:Q8IWW2 xref: UniProtKB:Q8N3A1 xref: UniProtKB:Q9UMH2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022186 ! DHX29_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020541 ! dhx29-tbc1d17 physical interaction relationship: transforms_into CCO:B0065949 ! DHX29_HUMAN-Phosphoserine192 relationship: transforms_into CCO:B0065950 ! DHX29_HUMAN-Phosphoserine200 [Term] id: CCO:B0063507 name: LY6H_HUMAN def: "Lymphocyte antigen 6H precursor" [UniProtKB:O94772] synonym: "Ly-6H" EXACT [UniProtKB:O94772] xref: EMBL:AAH28894.1 xref: EMBL:AAH30192.1 xref: EMBL:BAA34115.1 xref: EMBL:CAG33315.1 xref: UniProtKB:O94772 xref: UniProtKB:Q6IAX0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022380 ! LY6H_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001149 ! anchored to membrane relationship: participates_in CCO:I0020546 ! dvl3-ly6h physical interaction [Term] id: CCO:B0063508 name: ICLN_HUMAN def: "Methylosome subunit pICln" [UniProtKB:P54105] synonym: "Chloride channel, nucleotide sensitive 1A" EXACT [UniProtKB:P54105] synonym: "Chloride conductance regulatory protein ICln" EXACT [UniProtKB:P54105] synonym: "Chloride ion current inducer protein" EXACT [UniProtKB:P54105] synonym: "ClCI" EXACT [UniProtKB:P54105] synonym: "I(Cln)" EXACT [UniProtKB:P54105] synonym: "Reticulocyte pICln" EXACT [UniProtKB:P54105] xref: EMBL:AAB03316.1 xref: EMBL:AAB61444.1 xref: EMBL:AAB88806.1 xref: EMBL:AAC50111.1 xref: EMBL:AAF76858.1 xref: EMBL:AAF76859.1 xref: EMBL:AAF76861.1 xref: EMBL:AAI19635.1 xref: EMBL:AAI19636.1 xref: EMBL:AAV38710.1 xref: EMBL:CAA62902.1 xref: UniProtKB:P54105 xref: UniProtKB:Q0VDK6 xref: UniProtKB:Q9NRD2 xref: UniProtKB:Q9NRD3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022328 ! CLNS1A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020547 ! eif4a2-clns1a physical interaction relationship: transforms_into CCO:B0067001 ! ICLN_HUMAN-N-acetylserine2 relationship: transforms_into CCO:B0067002 ! ICLN_HUMAN-Phosphoserine102 relationship: transforms_into CCO:B0067003 ! ICLN_HUMAN-Phosphoserine193 relationship: transforms_into CCO:B0067004 ! ICLN_HUMAN-Phosphothreonine223 [Term] id: CCO:B0063509 name: Q75KN0_HUMAN def: "Putative uncharacterized protein FLJ10842" [UniProtKB:Q75KN0] xref: EMBL:AAS07538.1 xref: UniProtKB:Q75KN0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022841 ! FLJ10842_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020557 ! flj10842-pdlim1 physical interaction [Term] id: CCO:B0063510 name: PTCD3_HUMAN def: "Pentatricopeptide repeat-containing protein 3, mitochondrial precursor" [UniProtKB:Q96EY7] synonym: "Transformation-related gene 15 protein" EXACT [UniProtKB:Q96EY7] synonym: "TRG-15" EXACT [UniProtKB:Q96EY7] xref: EMBL:AAH01758.3 xref: EMBL:AAH11832.3 xref: EMBL:AAQ18037.1 xref: EMBL:BAA91370.1 xref: EMBL:CAH56345.1 xref: UniProtKB:A6NHD2 xref: UniProtKB:Q597H0 xref: UniProtKB:Q658Y9 xref: UniProtKB:Q96EY7 xref: UniProtKB:Q9BUZ8 xref: UniProtKB:Q9NWL0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022537 ! PTCD3_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: participates_in CCO:I0020558 ! flj20758-tbpl1 physical interaction [Term] id: CCO:B0063511 name: Q96I30_HUMAN def: "GPR108 protein" [UniProtKB:Q96I30] xref: EMBL:AAH07862.1 xref: UniProtKB:Q96I30 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022855 ! GPR108_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020562 ! glra2-gpr108 physical interaction [Term] id: CCO:B0063512 name: Q6IBL2_HUMAN def: "OS-9 protein" [UniProtKB:Q6IBL2] xref: EMBL:CAG33072.1 xref: UniProtKB:Q6IBL2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022837 ! OS-9_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020578 ! itgb3bp-os_9 physical interaction [Term] id: CCO:B0063513 name: S35E1_HUMAN def: "Solute carrier family 35 member E1" [UniProtKB:Q96K37] xref: EMBL:AAH14557.1 xref: EMBL:AAH62562.1 xref: EMBL:BAB55306.1 xref: EMBL:BAB55410.1 xref: EMBL:BAC11565.1 xref: EMBL:CAE45863.1 xref: UniProtKB:Q8NBQ2 xref: UniProtKB:Q96JV7 xref: UniProtKB:Q96K37 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022631 ! SLC35E1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020581 ! lama3-slc35e1 physical interaction relationship: transforms_into CCO:B0070284 ! S35E1_HUMAN-Phosphothreonine352 relationship: transforms_into CCO:B0070285 ! S35E1_HUMAN-Phosphoserine363 [Term] id: CCO:B0063514 name: LAMA3_HUMAN def: "Laminin subunit alpha-3 precursor" [UniProtKB:Q16787] synonym: "E170" EXACT [UniProtKB:Q16787] synonym: "Epiligrin 170 kDa subunit" EXACT [UniProtKB:Q16787] synonym: "Nicein subunit alpha" EXACT [UniProtKB:Q16787] xref: EMBL:AAA59483.1 xref: EMBL:AAQ72570.1 xref: EMBL:BAD13428.1 xref: EMBL:CAA59325.1 xref: EMBL:CAA59428.1 xref: EMBL:CAA59429.1 xref: UniProtKB:Q13679 xref: UniProtKB:Q13680 xref: UniProtKB:Q16787 xref: UniProtKB:Q6VU68 xref: UniProtKB:Q76E14 xref: UniProtKB:Q96TG0 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0021057 ! LAMA3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020581 ! lama3-slc35e1 physical interaction [Term] id: CCO:B0063515 name: F100A_HUMAN def: "Protein FAM100A" [UniProtKB:Q8TB05] xref: EMBL:AAH12018.1 xref: EMBL:AAH25327.1 xref: EMBL:AAH62534.1 xref: EMBL:AAQ04656.1 xref: UniProtKB:Q71MF6 xref: UniProtKB:Q8TB05 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022232 ! FAM100A_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020584 ! loc124402-med8 physical interaction [Term] id: CCO:B0063516 name: M6PBP_HUMAN def: "Mannose-6-phosphate receptor-binding protein 1" [UniProtKB:O60664] synonym: "47 kDa mannose 6-phosphate receptor-binding protein" EXACT [UniProtKB:O60664] synonym: "47 kDa MPR-binding protein" EXACT [UniProtKB:O60664] synonym: "Cargo selection protein TIP47" EXACT [UniProtKB:O60664] synonym: "Placental protein 17" EXACT [UniProtKB:O60664] synonym: "PP17" EXACT [UniProtKB:O60664] xref: EMBL:AAC39751.1 xref: EMBL:AAD11619.1 xref: EMBL:AAD11620.1 xref: EMBL:AAD11622.1 xref: EMBL:AAH01590.1 xref: EMBL:AAH05818.1 xref: EMBL:AAH07566.1 xref: EMBL:AAH19278.1 xref: EMBL:AAP35899.1 xref: EMBL:BAD96774.1 xref: UniProtKB:O60664 xref: UniProtKB:Q53G77 xref: UniProtKB:Q9BS03 xref: UniProtKB:Q9UBD7 xref: UniProtKB:Q9UP92 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022384 ! M6PRBP1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000382 ! lipid particle relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002166 ! monolayer-surrounded lipid storage body outer lipid monolayer relationship: participates_in CCO:I0020587 ! m6prbp1-tbpl1 physical interaction [Term] id: CCO:B0063517 name: B3GNL_HUMAN def: "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1" [UniProtKB:Q67FW5] synonym: "Beta1,3-N-acetylglucosaminyltransferase-like protein 1" EXACT [UniProtKB:Q67FW5] synonym: "Beta3Gn-T-like protein 1" EXACT [UniProtKB:Q67FW5] synonym: "Beta3Gn-T8" EXACT [UniProtKB:Q67FW5] synonym: "Beta3GnTL1" EXACT [UniProtKB:Q67FW5] synonym: "BGnT-8" EXACT [UniProtKB:Q67FW5] synonym: "BGnT-like protein 1" EXACT [UniProtKB:Q67FW5] synonym: "EC 2.4.1.-" EXACT [UniProtKB:Q67FW5] xref: EMBL:AAH19623.1 xref: EMBL:AAQ74775.1 xref: EMBL:AAT47555.1 xref: UniProtKB:Q67FW5 xref: UniProtKB:Q6GV30 xref: UniProtKB:Q8WUT3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022065 ! B3GNTL1_human relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020594 ! mpp3-b3gntl1 physical interaction [Term] id: CCO:B0063518 name: IDUA_HUMAN def: "Alpha-L-iduronidase precursor" [UniProtKB:P35475] synonym: "EC 3.2.1.76" EXACT [UniProtKB:P35475] xref: EMBL:AAA51698.1 xref: EMBL:AAA81589.1 xref: UniProtKB:P35475 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022332 ! IDUA_human relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000434 ! L-iduronidase activity relationship: has_function CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0005808 ! cation binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: participates_in CCO:I0020596 ! mpp3-idua physical interaction [Term] id: CCO:B0063519 name: KBTB4_HUMAN def: "Kelch repeat and BTB domain-containing protein 4" [UniProtKB:Q9NVX7] synonym: "BTB and kelch domain-containing protein 4" EXACT [UniProtKB:Q9NVX7] xref: EMBL:AAH02736.1 xref: EMBL:BAA91616.1 xref: EMBL:BAA91880.1 xref: EMBL:CAD28521.1 xref: EMBL:CAG33551.1 xref: UniProtKB:Q6IA85 xref: UniProtKB:Q9BUC3 xref: UniProtKB:Q9NV76 xref: UniProtKB:Q9NVX7 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022347 ! KBTBD4_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020598 ! mpp3-kbtbd4 physical interaction [Term] id: CCO:B0063520 name: MORN2_HUMAN def: "MORN repeat-containing protein 2" [UniProtKB:Q502X0] synonym: "MORN motif protein in testis" EXACT [UniProtKB:Q502X0] xref: EMBL:AAH95472.1 xref: EMBL:AAI02033.1 xref: EMBL:AAI02035.1 xref: EMBL:AAI02036.1 xref: EMBL:AAQ73170.1 xref: UniProtKB:Q502X0 xref: UniProtKB:Q6UL00 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022405 ! MORN2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020599 ! mpp3-mopt physical interaction relationship: transforms_into CCO:B0068250 ! MORN2_HUMAN-Phosphotyrosine38 [Term] id: CCO:B0063521 name: RAB31_HUMAN def: "Ras-related protein Rab-31" [UniProtKB:Q13636] synonym: "Rab-22B" EXACT [UniProtKB:Q13636] xref: EMBL:AAB02832.1 xref: EMBL:AAC50773.1 xref: EMBL:AAG09690.1 xref: EMBL:AAG13847.1 xref: EMBL:AAH01148.1 xref: EMBL:AAM21105.1 xref: EMBL:AAV38830.1 xref: EMBL:AAV38831.1 xref: EMBL:CAG28587.1 xref: UniProtKB:Q13636 xref: UniProtKB:Q15770 xref: UniProtKB:Q9HC00 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022553 ! RAB31_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020600 ! mpp3-rab31 physical interaction relationship: transforms_into CCO:B0069675 ! RAB31_HUMAN-Phosphoserine35 [Term] id: CCO:B0063522 name: TMM51_HUMAN def: "Transmembrane protein 51" [UniProtKB:Q9NW97] xref: EMBL:AAH00202.1 xref: EMBL:AAH00593.1 xref: EMBL:BAA91486.1 xref: EMBL:CAG33401.1 xref: EMBL:CAI23267.1 xref: UniProtKB:Q9NW97 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022723 ! TMEM51_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020603 ! mrpl12-tmem51 physical interaction relationship: transforms_into CCO:B0071433 ! TMM51_HUMAN-Phosphoserine115 [Term] id: CCO:B0063523 name: RM38_HUMAN def: "39S ribosomal protein L38, mitochondrial precursor" [UniProtKB:Q96DV4] synonym: "L38mt" EXACT [UniProtKB:Q96DV4] synonym: "MRP-L38" EXACT [UniProtKB:Q96DV4] xref: EMBL:AAF28940.1 xref: EMBL:AAH13311.1 xref: EMBL:BAB54935.1 xref: UniProtKB:Q96DV4 xref: UniProtKB:Q96Q66 xref: UniProtKB:Q9P0B9 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022587 ! MRPL38_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: participates_in CCO:I0020604 ! mrpl38-prim1 physical interaction [Term] id: CCO:B0063524 name: Q9HC74_HUMAN def: "Putative uncharacterized protein SBBI23" [UniProtKB:Q9HC74] xref: EMBL:AAG27922.1 xref: UniProtKB:Q9HC74 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0005592 ! SEPT9_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020605 ! sept9-rab10 physical interaction [Term] id: CCO:B0063525 name: NOVA1_HUMAN def: "RNA-binding protein Nova-1" [UniProtKB:P51513] synonym: "Neuro-oncological ventral antigen 1" EXACT [UniProtKB:P51513] synonym: "Onconeural ventral antigen 1" EXACT [UniProtKB:P51513] synonym: "Paraneoplastic Ri antigen" EXACT [UniProtKB:P51513] synonym: "Ventral neuron-specific protein 1" EXACT [UniProtKB:P51513] xref: EMBL:AAA16022.1 xref: EMBL:AAH75038.1 xref: EMBL:AAH75039.1 xref: EMBL:CAA94810.1 xref: UniProtKB:P51513 xref: UniProtKB:Q6B004 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022451 ! NOVA1_human relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: participates_in CCO:I0020609 ! nova1-smarcc2 physical interaction [Term] id: CCO:B0063526 name: NSF1C_HUMAN def: "NSFL1 cofactor p47" [UniProtKB:Q9UNZ2] synonym: "p97 cofactor p47" EXACT [UniProtKB:Q9UNZ2] synonym: "UBX domain-containing protein 2C" EXACT [UniProtKB:Q9UNZ2] xref: EMBL:AAD44488.1 xref: EMBL:AAF17199.1 xref: EMBL:AAH02801.1 xref: EMBL:AAP97139.1 xref: EMBL:BAA91731.1 xref: EMBL:CAB96827.1 xref: UniProtKB:Q7Z533 xref: UniProtKB:Q9H102 xref: UniProtKB:Q9NVL9 xref: UniProtKB:Q9UI06 xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022458 ! NSFL1C_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020610 ! nsfl1c-anp32a physical interaction relationship: participates_in CCO:I0020611 ! nsfl1c-glmn physical interaction relationship: participates_in CCO:I0020612 ! nsfl1c-srp14 physical interaction relationship: transforms_into CCO:B0068865 ! NSF1C_HUMAN-Phosphoserine74 relationship: transforms_into CCO:B0068866 ! NSF1C_HUMAN-Phosphoserine114 relationship: transforms_into CCO:B0068867 ! NSF1C_HUMAN-Phosphoserine140 relationship: transforms_into CCO:B0068868 ! NSF1C_HUMAN-Phosphoserine165 relationship: transforms_into CCO:B0068869 ! NSF1C_HUMAN-Phosphotyrosine167 relationship: transforms_into CCO:B0068870 ! NSF1C_HUMAN-Phosphoserine176 relationship: transforms_into CCO:B0068871 ! NSF1C_HUMAN-Phosphoserine272 [Term] id: CCO:B0063527 name: CDAN1_HUMAN def: "Codanin-1" [UniProtKB:Q8IWY9] xref: EMBL:AAH01092.1 xref: EMBL:AAH08333.1 xref: EMBL:AAH08334.1 xref: EMBL:AAH52568.1 xref: EMBL:AAH66640.1 xref: EMBL:AAO14994.1 xref: EMBL:AAQ88832.1 xref: UniProtKB:Q6NYD0 xref: UniProtKB:Q7Z7L5 xref: UniProtKB:Q8IWY9 xref: UniProtKB:Q969N3 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022110 ! CDAN1_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020624 ! pdpk1-cdan1 physical interaction [Term] id: CCO:B0063528 name: PA2GX_HUMAN def: "Group 10 secretory phospholipase A2 precursor" [UniProtKB:O15496] synonym: "EC 3.1.1.4" EXACT [UniProtKB:O15496] synonym: "Group X secretory phospholipase A2" EXACT [UniProtKB:O15496] synonym: "GX sPLA2" EXACT [UniProtKB:O15496] synonym: "Phosphatidylcholine 2-acylhydrolase GX" EXACT [UniProtKB:O15496] synonym: "sPLA2-X" EXACT [UniProtKB:O15496] xref: EMBL:AAB64410.1 xref: EMBL:AAH69539.1 xref: EMBL:AAI06732.1 xref: EMBL:AAI06733.1 xref: EMBL:CAG33166.1 xref: UniProtKB:O15496 xref: UniProtKB:Q6NT23 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022488 ! PLA2G10_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020627 ! pla2g10-myo10 physical interaction [Term] id: CCO:B0063529 name: SURF2_HUMAN def: "Surfeit locus protein 2" [UniProtKB:Q15527] synonym: "Surf-2" EXACT [UniProtKB:Q15527] xref: EMBL:AAH14411.1 xref: EMBL:CAA84477.1 xref: UniProtKB:Q15527 xref: UniProtKB:Q96CD1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022687 ! SURF2_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020628 ! plaur-surf2 physical interaction relationship: transforms_into CCO:B0070997 ! SURF2_HUMAN-Phosphothreonine154 relationship: transforms_into CCO:B0070998 ! SURF2_HUMAN-Phosphoserine155 relationship: transforms_into CCO:B0070999 ! SURF2_HUMAN-Phosphoserine156 relationship: transforms_into CCO:B0071000 ! SURF2_HUMAN-Phosphoserine163 relationship: transforms_into CCO:B0071001 ! SURF2_HUMAN-Phosphothreonine190 relationship: transforms_into CCO:B0071002 ! SURF2_HUMAN-Phosphothreonine195 [Term] id: CCO:B0063530 name: NCPR_HUMAN def: "NADPH--cytochrome P450 reductase" [UniProtKB:P16435] synonym: "CPR" EXACT [UniProtKB:P16435] synonym: "EC 1.6.2.4" EXACT [UniProtKB:P16435] synonym: "P450R" EXACT [UniProtKB:P16435] xref: EMBL:AAB21814.1 xref: EMBL:AAG09798.1 xref: EMBL:AAH34277.1 xref: EMBL:BAB18572.1 xref: UniProtKB:P16435 xref: UniProtKB:Q16455 xref: UniProtKB:Q8N181 xref: UniProtKB:Q9H3M8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022432 ! POR_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020629 ! por-g22p1 physical interaction relationship: transforms_into CCO:B0068520 ! NCPR_HUMAN-N-acetylglycine2 relationship: transforms_into CCO:B0068521 ! NCPR_HUMAN-Phosphotyrosine575 [Term] id: CCO:B0063531 name: CLCB_HUMAN def: "Clathrin light chain B" [UniProtKB:P09497] synonym: "Lcb" EXACT [UniProtKB:P09497] xref: EMBL:AAA51818.1 xref: EMBL:AAA59506.1 xref: EMBL:AAH06332.1 xref: EMBL:AAH06457.1 xref: EMBL:CAG38814.1 xref: UniProtKB:P09497 xref: UniProtKB:Q6FHW1 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022136 ! CLTB_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000963 ! clathrin coat relationship: located_in CCO:C0000975 ! clathrin coat of trans-Golgi network vesicle relationship: located_in CCO:C0000977 ! clathrin coat of coated pit relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: participates_in CCO:I0020631 ! pqbp1-cltb physical interaction relationship: transforms_into CCO:B0065878 ! CLCB_HUMAN-Phosphoserine11 relationship: transforms_into CCO:B0065879 ! CLCB_HUMAN-Phosphoserine13 [Term] id: CCO:B0063532 name: APMAP_HUMAN def: "Adipocyte plasma membrane-associated protein" [UniProtKB:Q9HDC9] synonym: "BSCv protein" EXACT [UniProtKB:Q9HDC9] xref: EMBL:AAH03501.1 xref: EMBL:AAQ89435.1 xref: EMBL:BAB11885.1 xref: EMBL:BAB15253.1 xref: EMBL:BAB15578.1 xref: EMBL:CAB75499.1 xref: UniProtKB:Q6UVZ8 xref: UniProtKB:Q9GZS8 xref: UniProtKB:Q9HDC9 xref: UniProtKB:Q9NUB2 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022044 ! APMAP_human relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0003409 ! strictosidine synthase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: participates_in CCO:I0020648 ! rasa4-apmap physical interaction [Term] id: CCO:B0063533 name: IFRD1_HUMAN def: "Interferon-related developmental regulator 1" [UniProtKB:O00458] synonym: "Nerve growth factor-inducible protein PC4" EXACT [UniProtKB:O00458] xref: EMBL:AAC24562.1 xref: EMBL:AAH01272.1 xref: EMBL:AAV38692.1 xref: EMBL:AAV38693.1 xref: EMBL:CAA71366.1 xref: UniProtKB:O00458 xref: UniProtKB:O75234 xref: UniProtKB:Q5U013 xref: UniProtKB:Q9BVE4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022335 ! IFRD1_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020653 ! rit1-ifrd1 physical interaction relationship: transforms_into CCO:B0067061 ! IFRD1_HUMAN-Phosphoserine21 [Term] id: CCO:B0063534 name: SPYA_HUMAN def: "Serine--pyruvate aminotransferase" [UniProtKB:P21549] synonym: "AGT" EXACT [UniProtKB:P21549] synonym: "Alanine--glyoxylate aminotransferase" EXACT [UniProtKB:P21549] synonym: "EC 2.6.1.44" EXACT [UniProtKB:P21549] synonym: "EC 2.6.1.51" EXACT [UniProtKB:P21549] synonym: "SPT" EXACT [UniProtKB:P21549] xref: EMBL:AAA51680.1 xref: EMBL:BAA02632.1 xref: EMBL:CAA37493.1 xref: EMBL:CAA39572.1 xref: UniProtKB:P21549 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022674 ! AGXT_human relationship: has_function CCO:F0001123 ! serine-pyruvate transaminase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001916 ! alanine-glyoxylate transaminase activity relationship: has_function CCO:F0001944 ! transaminase activity relationship: has_function CCO:F0003212 ! amino acid binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000359 ! peroxisome relationship: participates_in CCO:I0020667 ! sncaip-agxt physical interaction [Term] id: CCO:B0063535 name: SNX24_HUMAN def: "Sorting nexin-24" [UniProtKB:Q9Y343] xref: EMBL:AAD32668.1 xref: EMBL:AAH10886.1 xref: EMBL:AAH69012.1 xref: EMBL:AAK98769.1 xref: EMBL:AAQ88465.1 xref: UniProtKB:Q6UY33 xref: UniProtKB:Q9Y343 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022666 ! SNX24_human relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020669 ! snx24-sh3gl3 physical interaction [Term] id: CCO:B0063536 name: CK061_HUMAN def: "Uncharacterized protein C11orf61" [UniProtKB:Q6P1R3] xref: EMBL:AAH64919.1 xref: EMBL:BAB15618.1 xref: EMBL:CAC21648.1 xref: UniProtKB:Q6P1R3 xref: UniProtKB:Q9H042 xref: UniProtKB:Q9H5K8 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022129 ! C11orf61_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020672 ! strn4-flj23342 physical interaction relationship: transforms_into CCO:B0065875 ! CK061_HUMAN-Phosphoserine48 relationship: transforms_into CCO:B0065876 ! CK061_HUMAN-Phosphoserine436 [Term] id: CCO:B0063537 name: CX026_HUMAN def: "UPF0368 protein Cxorf26" [UniProtKB:Q9BVG4] xref: EMBL:AAH01220.1 xref: EMBL:AAH51894.1 xref: UniProtKB:Q9BVG4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022163 ! CXorf26_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020673 ! strn4-cxorf26 physical interaction relationship: transforms_into CCO:B0065915 ! CX026_HUMAN-Phosphoserine126 relationship: transforms_into CCO:B0065916 ! CX026_HUMAN-Phosphoserine197 [Term] id: CCO:B0063538 name: TMM22_HUMAN def: "Transmembrane protein 22" [UniProtKB:Q8TBE7] xref: EMBL:AAH00111.1 xref: EMBL:AAH22557.1 xref: EMBL:CAB66596.1 xref: UniProtKB:Q8TBE7 xref: UniProtKB:Q9BWN4 xref: UniProtKB:Q9H0S6 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022721 ! TMEM22_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020678 ! tmem22-centb5 physical interaction relationship: transforms_into CCO:B0071432 ! TMM22_HUMAN-Phosphoserine409 [Term] id: CCO:B0063539 name: TRI16_HUMAN def: "Tripartite motif-containing protein 16" [UniProtKB:O95361] synonym: "Estrogen-responsive B box protein" EXACT [UniProtKB:O95361] xref: EMBL:AAC79080.1 xref: EMBL:AAH01564.1 xref: EMBL:AAH53514.1 xref: EMBL:AAH67096.1 xref: UniProtKB:O95361 xref: UniProtKB:Q7Z6I2 xref: UniProtKB:Q96BE8 xref: UniProtKB:Q96J43 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022733 ! TRIM16_human relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: participates_in CCO:I0020681 ! trim16-setdb1 physical interaction relationship: transforms_into CCO:B0071550 ! TRI16_HUMAN-Phosphoserine60 [Term] id: CCO:B0063540 name: WDR3_HUMAN def: "WD repeat-containing protein 3" [UniProtKB:Q9UNX4] xref: EMBL:AAD45865.1 xref: UniProtKB:Q9UNX4 is_a: CCO:U0000007 ! cell cycle protein relationship: encoded_by CCO:G0022783 ! WDR3_human relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: participates_in CCO:I0020687 ! wdr3-pde10a physical interaction relationship: transforms_into CCO:B0071836 ! WDR3_HUMAN-Phosphoserine240 relationship: transforms_into CCO:B0071837 ! WDR3_HUMAN-Phosphoserine241 relationship: transforms_into CCO:B0071838 ! WDR3_HUMAN-Phosphotyrosine723 [Term] id: CCO:B0063541 name: ARHG7_HUMAN-Phosphoserine518 def: "Protein ARHG7_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:Q14155] xref: UniProtKB:Q14155 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055966 ! ARHG7_HUMAN [Term] id: CCO:B0063542 name: ARHG7_HUMAN-Phosphoserine694 def: "Protein ARHG7_HUMAN with the residue 694 substituted with Phosphoserine" [UniProtKB:Q14155] xref: UniProtKB:Q14155 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055966 ! ARHG7_HUMAN [Term] id: CCO:B0063543 name: ARHG8_HUMAN-Phosphoserine100 def: "Protein ARHG8_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q7Z628] xref: UniProtKB:Q7Z628 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057190 ! ARHG8_HUMAN [Term] id: CCO:B0063544 name: ARHG8_HUMAN-Phosphoserine106 def: "Protein ARHG8_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q7Z628] xref: UniProtKB:Q7Z628 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057190 ! ARHG8_HUMAN [Term] id: CCO:B0063545 name: ARHGB_HUMAN-Phosphoserine663 def: "Protein ARHGB_HUMAN with the residue 663 substituted with Phosphoserine" [UniProtKB:O15085] xref: UniProtKB:O15085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054404 ! ARHGB_HUMAN [Term] id: CCO:B0063546 name: ARHGB_HUMAN-Phosphothreonine668 def: "Protein ARHGB_HUMAN with the residue 668 substituted with Phosphothreonine" [UniProtKB:O15085] xref: UniProtKB:O15085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054404 ! ARHGB_HUMAN [Term] id: CCO:B0063547 name: ARHGB_HUMAN-Phosphothreonine672 def: "Protein ARHGB_HUMAN with the residue 672 substituted with Phosphothreonine" [UniProtKB:O15085] xref: UniProtKB:O15085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054404 ! ARHGB_HUMAN [Term] id: CCO:B0063548 name: ARHGB_HUMAN-Phosphoserine1155 def: "Protein ARHGB_HUMAN with the residue 1155 substituted with Phosphoserine" [UniProtKB:O15085] xref: UniProtKB:O15085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054404 ! ARHGB_HUMAN [Term] id: CCO:B0063549 name: ARHGC_HUMAN-Phosphoserine41 def: "Protein ARHGC_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q9NZN5] xref: UniProtKB:Q9NZN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059006 ! ARHGC_HUMAN [Term] id: CCO:B0063550 name: ARHGC_HUMAN-Phosphoserine341 def: "Protein ARHGC_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q9NZN5] xref: UniProtKB:Q9NZN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059006 ! ARHGC_HUMAN [Term] id: CCO:B0063551 name: ARHGC_HUMAN-Phosphothreonine736 def: "Protein ARHGC_HUMAN with the residue 736 substituted with Phosphothreonine" [UniProtKB:Q9NZN5] xref: UniProtKB:Q9NZN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059006 ! ARHGC_HUMAN [Term] id: CCO:B0063552 name: ARHGC_HUMAN-Phosphoserine1288 def: "Protein ARHGC_HUMAN with the residue 1288 substituted with Phosphoserine" [UniProtKB:Q9NZN5] xref: UniProtKB:Q9NZN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059006 ! ARHGC_HUMAN [Term] id: CCO:B0063553 name: ARHGG_HUMAN-Phosphoserine41 def: "Protein ARHGG_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063554 name: ARHGG_HUMAN-Phosphoserine107 def: "Protein ARHGG_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063555 name: ARHGG_HUMAN-Phosphoserine174 def: "Protein ARHGG_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063556 name: ARHGG_HUMAN-Phosphoserine208 def: "Protein ARHGG_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063557 name: ARHGG_HUMAN-Phosphoserine227 def: "Protein ARHGG_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063558 name: ARHGG_HUMAN-Phosphoserine230 def: "Protein ARHGG_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063559 name: ARHGG_HUMAN-Phosphoserine240 def: "Protein ARHGG_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063560 name: ARHGG_HUMAN-Phosphoserine577 def: "Protein ARHGG_HUMAN with the residue 577 substituted with Phosphoserine" [UniProtKB:Q5VV41] xref: UniProtKB:Q5VV41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056657 ! ARHGG_HUMAN [Term] id: CCO:B0063561 name: ARHGH_HUMAN-Phosphoserine138 def: "Protein ARHGH_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q96PE2] xref: UniProtKB:Q96PE2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058330 ! ARHGH_HUMAN [Term] id: CCO:B0063562 name: ARHGI_HUMAN-Phosphoserine209 def: "Protein ARHGI_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q6ZSZ5] xref: UniProtKB:Q6ZSZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057060 ! ARHGI_HUMAN [Term] id: CCO:B0063563 name: ARHGI_HUMAN-Phosphothreonine212 def: "Protein ARHGI_HUMAN with the residue 212 substituted with Phosphothreonine" [UniProtKB:Q6ZSZ5] xref: UniProtKB:Q6ZSZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057060 ! ARHGI_HUMAN [Term] id: CCO:B0063564 name: ARHGI_HUMAN-Phosphoserine733 def: "Protein ARHGI_HUMAN with the residue 733 substituted with Phosphoserine" [UniProtKB:Q6ZSZ5] xref: UniProtKB:Q6ZSZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057060 ! ARHGI_HUMAN [Term] id: CCO:B0063565 name: ARHGI_HUMAN-Phosphoserine1101 def: "Protein ARHGI_HUMAN with the residue 1101 substituted with Phosphoserine" [UniProtKB:Q6ZSZ5] xref: UniProtKB:Q6ZSZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057060 ! ARHGI_HUMAN [Term] id: CCO:B0063566 name: ARHGI_HUMAN-Phosphoserine1103 def: "Protein ARHGI_HUMAN with the residue 1103 substituted with Phosphoserine" [UniProtKB:Q6ZSZ5] xref: UniProtKB:Q6ZSZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057060 ! ARHGI_HUMAN [Term] id: CCO:B0063567 name: ARHGI_HUMAN-Phosphoserine1124 def: "Protein ARHGI_HUMAN with the residue 1124 substituted with Phosphoserine" [UniProtKB:Q6ZSZ5] xref: UniProtKB:Q6ZSZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057060 ! ARHGI_HUMAN [Term] id: CCO:B0063568 name: ARHGI_HUMAN-Phosphoserine1130 def: "Protein ARHGI_HUMAN with the residue 1130 substituted with Phosphoserine" [UniProtKB:Q6ZSZ5] xref: UniProtKB:Q6ZSZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057060 ! ARHGI_HUMAN [Term] id: CCO:B0063569 name: ARH_HUMAN-Phosphoserine14 def: "Protein ARH_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q5SW96] xref: UniProtKB:Q5SW96 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056547 ! ARH_HUMAN [Term] id: CCO:B0063570 name: ARH_HUMAN-Phosphoserine186 def: "Protein ARH_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:Q5SW96] xref: UniProtKB:Q5SW96 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056547 ! ARH_HUMAN [Term] id: CCO:B0063571 name: ARI1B_HUMAN-Phosphoserine516 def: "Protein ARI1B_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q8NFD5] xref: UniProtKB:Q8NFD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:B0063572 name: ARI1B_HUMAN-Phosphoserine1555 def: "Protein ARI1B_HUMAN with the residue 1555 substituted with Phosphoserine" [UniProtKB:Q8NFD5] xref: UniProtKB:Q8NFD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:B0063573 name: ARI1B_HUMAN-Phosphoserine1559 def: "Protein ARI1B_HUMAN with the residue 1559 substituted with Phosphoserine" [UniProtKB:Q8NFD5] xref: UniProtKB:Q8NFD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000799 ! SWI/SNF complex relationship: transformation_of CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:B0063574 name: ARI3A_HUMAN-Phosphoserine77 def: "Protein ARI3A_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q99856] xref: UniProtKB:Q99856 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058459 ! ARI3A_HUMAN [Term] id: CCO:B0063575 name: ARI3A_HUMAN-Phosphoserine81 def: "Protein ARI3A_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:Q99856] xref: UniProtKB:Q99856 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058459 ! ARI3A_HUMAN [Term] id: CCO:B0063576 name: ARI3A_HUMAN-Phosphoserine88 def: "Protein ARI3A_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q99856] xref: UniProtKB:Q99856 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058459 ! ARI3A_HUMAN [Term] id: CCO:B0063577 name: ARI3B_HUMAN-Phosphoserine89 def: "Protein ARI3B_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q8IVW6] xref: UniProtKB:Q8IVW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057349 ! ARI3B_HUMAN [Term] id: CCO:B0063578 name: ARI4B_HUMAN-Phosphoserine666 def: "Protein ARI4B_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063579 name: ARI4B_HUMAN-Phosphoserine675 def: "Protein ARI4B_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063580 name: ARI4B_HUMAN-Phosphoserine778 def: "Protein ARI4B_HUMAN with the residue 778 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063581 name: ARI4B_HUMAN-Phosphoserine790 def: "Protein ARI4B_HUMAN with the residue 790 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063582 name: ARI4B_HUMAN-Phosphothreonine793 def: "Protein ARI4B_HUMAN with the residue 793 substituted with Phosphothreonine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063583 name: ARI4B_HUMAN-Phosphoserine912 def: "Protein ARI4B_HUMAN with the residue 912 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063584 name: ARI4B_HUMAN-Phosphothreonine1150 def: "Protein ARI4B_HUMAN with the residue 1150 substituted with Phosphothreonine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063585 name: ARI4B_HUMAN-Phosphoserine1152 def: "Protein ARI4B_HUMAN with the residue 1152 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063586 name: ARI4B_HUMAN-Phosphoserine1153 def: "Protein ARI4B_HUMAN with the residue 1153 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063587 name: ARI4B_HUMAN-Phosphoserine1155 def: "Protein ARI4B_HUMAN with the residue 1155 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063588 name: ARI4B_HUMAN-Phosphoserine1159 def: "Protein ARI4B_HUMAN with the residue 1159 substituted with Phosphoserine" [UniProtKB:Q4LE39] xref: UniProtKB:Q4LE39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0026855 ! ARI4B_HUMAN [Term] id: CCO:B0063589 name: ARID2_HUMAN-Phosphoserine631 def: "Protein ARID2_HUMAN with the residue 631 substituted with Phosphoserine" [UniProtKB:Q68CP9] xref: UniProtKB:Q68CP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:B0063590 name: ARID2_HUMAN-Phosphoserine635 def: "Protein ARID2_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:Q68CP9] xref: UniProtKB:Q68CP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:B0063591 name: ARID2_HUMAN-Phosphothreonine653 def: "Protein ARID2_HUMAN with the residue 653 substituted with Phosphothreonine" [UniProtKB:Q68CP9] xref: UniProtKB:Q68CP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:B0063592 name: ARID2_HUMAN-Phosphoserine689 def: "Protein ARID2_HUMAN with the residue 689 substituted with Phosphoserine" [UniProtKB:Q68CP9] xref: UniProtKB:Q68CP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:B0063593 name: ARID2_HUMAN-Phosphothreonine692 def: "Protein ARID2_HUMAN with the residue 692 substituted with Phosphothreonine" [UniProtKB:Q68CP9] xref: UniProtKB:Q68CP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:B0063594 name: ARID2_HUMAN-Phosphoserine1496 def: "Protein ARID2_HUMAN with the residue 1496 substituted with Phosphoserine" [UniProtKB:Q68CP9] xref: UniProtKB:Q68CP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:B0063595 name: ARL11_HUMAN-Phosphoserine6 def: "Protein ARL11_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q969Q4] xref: UniProtKB:Q969Q4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058138 ! ARL11_HUMAN [Term] id: CCO:B0063596 name: ARL14_HUMAN-Phosphotyrosine31 def: "Protein ARL14_HUMAN with the residue 31 substituted with Phosphotyrosine" [UniProtKB:Q8N4G2] xref: UniProtKB:Q8N4G2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057466 ! ARL14_HUMAN [Term] id: CCO:B0063597 name: ARM10_HUMAN-Phosphoserine45 def: "Protein ARM10_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q8N2F6] xref: UniProtKB:Q8N2F6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057443 ! ARM10_HUMAN [Term] id: CCO:B0063598 name: ARMS_HUMAN-Phosphoserine918 def: "Protein ARMS_HUMAN with the residue 918 substituted with Phosphoserine" [UniProtKB:Q9ULH0] xref: UniProtKB:Q9ULH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059224 ! ARMS_HUMAN [Term] id: CCO:B0063599 name: ARMS_HUMAN-Phosphoserine1294 def: "Protein ARMS_HUMAN with the residue 1294 substituted with Phosphoserine" [UniProtKB:Q9ULH0] xref: UniProtKB:Q9ULH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059224 ! ARMS_HUMAN [Term] id: CCO:B0063600 name: ARMS_HUMAN-Phosphoserine1359 def: "Protein ARMS_HUMAN with the residue 1359 substituted with Phosphoserine" [UniProtKB:Q9ULH0] xref: UniProtKB:Q9ULH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059224 ! ARMS_HUMAN [Term] id: CCO:B0063601 name: ARMS_HUMAN-Phosphoserine1362 def: "Protein ARMS_HUMAN with the residue 1362 substituted with Phosphoserine" [UniProtKB:Q9ULH0] xref: UniProtKB:Q9ULH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059224 ! ARMS_HUMAN [Term] id: CCO:B0063602 name: ARMS_HUMAN-Phosphoserine1365 def: "Protein ARMS_HUMAN with the residue 1365 substituted with Phosphoserine" [UniProtKB:Q9ULH0] xref: UniProtKB:Q9ULH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059224 ! ARMS_HUMAN [Term] id: CCO:B0063603 name: ARMS_HUMAN-Phosphoserine1521 def: "Protein ARMS_HUMAN with the residue 1521 substituted with Phosphoserine" [UniProtKB:Q9ULH0] xref: UniProtKB:Q9ULH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059224 ! ARMS_HUMAN [Term] id: CCO:B0063604 name: ARMS_HUMAN-Phosphoserine1526 def: "Protein ARMS_HUMAN with the residue 1526 substituted with Phosphoserine" [UniProtKB:Q9ULH0] xref: UniProtKB:Q9ULH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059224 ! ARMS_HUMAN [Term] id: CCO:B0063605 name: ARP11_HUMAN-Phosphotyrosine102 def: "Protein ARP11_HUMAN with the residue 102 substituted with Phosphotyrosine" [UniProtKB:Q9C0K3] comment: By similarity xref: UniProtKB:Q9C0K3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058623 ! ARP11_HUMAN [Term] id: CCO:B0063606 name: ARP19_HUMAN-N-acetylserine2 def: "Protein ARP19_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P56211] comment: in isoform ARPP-19; By similarity xref: UniProtKB:P56211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055542 ! ARP19_HUMAN [Term] id: CCO:B0063607 name: ARP19_HUMAN-N-acetylmethionine17 def: "Protein ARP19_HUMAN with the residue 17 substituted with N-acetylmethionine" [UniProtKB:P56211] comment: in isoform ARPP-16; By similarity xref: UniProtKB:P56211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055542 ! ARP19_HUMAN [Term] id: CCO:B0063608 name: ARP19_HUMAN-Phosphoserine62 def: "Protein ARP19_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:P56211] xref: UniProtKB:P56211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055542 ! ARP19_HUMAN [Term] id: CCO:B0063609 name: ARP19_HUMAN-Phosphoserine104 def: "Protein ARP19_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:P56211] comment: by PKA; By similarity xref: UniProtKB:P56211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0002867 ! potassium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055542 ! ARP19_HUMAN [Term] id: CCO:B0063610 name: ARP3_HUMAN-Phosphotyrosine16 def: "Protein ARP3_HUMAN with the residue 16 substituted with Phosphotyrosine" [UniProtKB:P61158] xref: UniProtKB:P61158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021502 ! ARP3_HUMAN [Term] id: CCO:B0063611 name: ARP3_HUMAN-Phosphotyrosine202 def: "Protein ARP3_HUMAN with the residue 202 substituted with Phosphotyrosine" [UniProtKB:P61158] xref: UniProtKB:P61158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021502 ! ARP3_HUMAN [Term] id: CCO:B0063612 name: ARP5L_HUMAN-Phosphoserine64 def: "Protein ARP5L_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q9BPX5] xref: UniProtKB:Q9BPX5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058471 ! ARP5L_HUMAN [Term] id: CCO:B0063613 name: ARP8_HUMAN-Phosphoserine412 def: "Protein ARP8_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:Q9H981] xref: UniProtKB:Q9H981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006058 ! ARP8_HUMAN [Term] id: CCO:B0063614 name: ARRB1_HUMAN-Phosphotyrosine47 def: "Protein ARRB1_HUMAN with the residue 47 substituted with Phosphotyrosine" [UniProtKB:P49407] comment: By similarity xref: UniProtKB:P49407 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055424 ! ARRB1_HUMAN [Term] id: CCO:B0063615 name: ARRB1_HUMAN-Phosphothreonine410 def: "Protein ARRB1_HUMAN with the residue 410 substituted with Phosphothreonine" [UniProtKB:P49407] comment: By similarity xref: UniProtKB:P49407 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0055424 ! ARRB1_HUMAN [Term] id: CCO:B0063616 name: ARRB1_HUMAN-Phosphoserine412 def: "Protein ARRB1_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:P49407] comment: By similarity xref: UniProtKB:P49407 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055424 ! ARRB1_HUMAN [Term] id: CCO:B0063617 name: ARRB2_HUMAN-Phosphotyrosine48 def: "Protein ARRB2_HUMAN with the residue 48 substituted with Phosphotyrosine" [UniProtKB:P32121] comment: By similarity xref: UniProtKB:P32121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055250 ! ARRB2_HUMAN [Term] id: CCO:B0063618 name: AS250_HUMAN-Phosphoserine373 def: "Protein AS250_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:Q2PPJ7] comment: By similarity xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063619 name: AS250_HUMAN-Phosphoserine376 def: "Protein AS250_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q2PPJ7] comment: By similarity xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063620 name: AS250_HUMAN-Phosphoserine379 def: "Protein AS250_HUMAN with the residue 379 substituted with Phosphoserine" [UniProtKB:Q2PPJ7] comment: By similarity xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063621 name: AS250_HUMAN-Phosphoserine486 def: "Protein AS250_HUMAN with the residue 486 substituted with Phosphoserine" [UniProtKB:Q2PPJ7] comment: by PKB; xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063622 name: AS250_HUMAN-Phosphoserine696 def: "Protein AS250_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:Q2PPJ7] comment: by PKB; xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063623 name: AS250_HUMAN-Phosphothreonine715 def: "Protein AS250_HUMAN with the residue 715 substituted with Phosphothreonine" [UniProtKB:Q2PPJ7] comment: by PKB; xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063624 name: AS250_HUMAN-Phosphoserine820 def: "Protein AS250_HUMAN with the residue 820 substituted with Phosphoserine" [UniProtKB:Q2PPJ7] xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063625 name: AS250_HUMAN-Phosphoserine821 def: "Protein AS250_HUMAN with the residue 821 substituted with Phosphoserine" [UniProtKB:Q2PPJ7] xref: UniProtKB:Q2PPJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056222 ! AS250_HUMAN [Term] id: CCO:B0063626 name: ASF1B_HUMAN-Phosphoserine142 def: "Protein ASF1B_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q9NVP2] xref: UniProtKB:Q9NVP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058932 ! ASF1B_HUMAN [Term] id: CCO:B0063627 name: ASGR2_HUMAN-Phosphoserine13 def: "Protein ASGR2_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P07307] comment: By similarity xref: UniProtKB:P07307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019143 ! ASGR2_HUMAN [Term] id: CCO:B0063628 name: ASH1L_HUMAN-Phosphoserine22 def: "Protein ASH1L_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:Q9NR48] xref: UniProtKB:Q9NR48 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0058886 ! ASH1L_HUMAN [Term] id: CCO:B0063629 name: ASH1L_HUMAN-Phosphoserine1681 def: "Protein ASH1L_HUMAN with the residue 1681 substituted with Phosphoserine" [UniProtKB:Q9NR48] xref: UniProtKB:Q9NR48 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058886 ! ASH1L_HUMAN [Term] id: CCO:B0063630 name: ASPP1_HUMAN-Phosphoserine681 def: "Protein ASPP1_HUMAN with the residue 681 substituted with Phosphoserine" [UniProtKB:Q96KQ4] xref: UniProtKB:Q96KQ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002046 ! ASPP1_HUMAN [Term] id: CCO:B0063631 name: ASPP2_HUMAN-Phosphoserine556 def: "Protein ASPP2_HUMAN with the residue 556 substituted with Phosphoserine" [UniProtKB:Q13625] xref: UniProtKB:Q13625 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001764 ! ASPP2_HUMAN [Term] id: CCO:B0063632 name: ASPP2_HUMAN-Phosphoserine569 def: "Protein ASPP2_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q13625] xref: UniProtKB:Q13625 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001764 ! ASPP2_HUMAN [Term] id: CCO:B0063633 name: ASXL1_HUMAN-Phosphoserine503 def: "Protein ASXL1_HUMAN with the residue 503 substituted with Phosphoserine" [UniProtKB:Q8IXJ9] comment: By similarity xref: UniProtKB:Q8IXJ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057379 ! ASXL1_HUMAN [Term] id: CCO:B0063634 name: ASXL2_HUMAN-Phosphoserine137 def: "Protein ASXL2_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q76L83] xref: UniProtKB:Q76L83 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057105 ! ASXL2_HUMAN [Term] id: CCO:B0063635 name: ASXL2_HUMAN-Phosphoserine139 def: "Protein ASXL2_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q76L83] xref: UniProtKB:Q76L83 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057105 ! ASXL2_HUMAN [Term] id: CCO:B0063636 name: ASXL2_HUMAN-Phosphoserine146 def: "Protein ASXL2_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q76L83] xref: UniProtKB:Q76L83 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057105 ! ASXL2_HUMAN [Term] id: CCO:B0063637 name: ASXL2_HUMAN-Phosphoserine517 def: "Protein ASXL2_HUMAN with the residue 517 substituted with Phosphoserine" [UniProtKB:Q76L83] xref: UniProtKB:Q76L83 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057105 ! ASXL2_HUMAN [Term] id: CCO:B0063638 name: ASXL2_HUMAN-Phosphoserine834 def: "Protein ASXL2_HUMAN with the residue 834 substituted with Phosphoserine" [UniProtKB:Q76L83] xref: UniProtKB:Q76L83 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057105 ! ASXL2_HUMAN [Term] id: CCO:B0063639 name: ASXL2_HUMAN-Phosphoserine845 def: "Protein ASXL2_HUMAN with the residue 845 substituted with Phosphoserine" [UniProtKB:Q76L83] xref: UniProtKB:Q76L83 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057105 ! ASXL2_HUMAN [Term] id: CCO:B0063640 name: AT10A_HUMAN-Phosphoserine646 def: "Protein AT10A_HUMAN with the residue 646 substituted with Phosphoserine" [UniProtKB:O60312] comment: By similarity xref: UniProtKB:O60312 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000490 ! phospholipid-translocating ATPase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054544 ! AT10A_HUMAN [Term] id: CCO:B0063641 name: AT1A3_HUMAN-Phosphoserine265 def: "Protein AT1A3_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:P13637] comment: By similarity xref: UniProtKB:P13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:B0063642 name: AT1A3_HUMAN-Phosphothreonine368 def: "Protein AT1A3_HUMAN with the residue 368 substituted with Phosphothreonine" [UniProtKB:P13637] comment: By similarity xref: UniProtKB:P13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001603 ! sodium:potassium-exchanging ATPase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002558 ! monovalent inorganic cation transmembrane transporter activity relationship: has_function CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000447 ! sodium:potassium-exchanging ATPase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:B0063643 name: AT1A3_HUMAN-Phosphotyrosine493 def: "Protein AT1A3_HUMAN with the residue 493 substituted with Phosphotyrosine" [UniProtKB:P13637] comment: By similarity xref: UniProtKB:P13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:B0063644 name: AT1A3_HUMAN-Phosphotyrosine548 def: "Protein AT1A3_HUMAN with the residue 548 substituted with Phosphotyrosine" [UniProtKB:P13637] comment: By similarity xref: UniProtKB:P13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:B0063645 name: AT1A3_HUMAN-Phosphotyrosine549 def: "Protein AT1A3_HUMAN with the residue 549 substituted with Phosphotyrosine" [UniProtKB:P13637] comment: By similarity xref: UniProtKB:P13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:B0063646 name: AT1A3_HUMAN-Phosphoserine933 def: "Protein AT1A3_HUMAN with the residue 933 substituted with Phosphoserine" [UniProtKB:P13637] comment: by PKA; By similarity xref: UniProtKB:P13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:B0063647 name: AT2A2_HUMAN-Nitrated tyrosine294 def: "Protein AT2A2_HUMAN with the residue 294 substituted with Nitrated tyrosine" [UniProtKB:P16615] xref: UniProtKB:P16615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:B0063648 name: AT2A2_HUMAN-Nitrated tyrosine295 def: "Protein AT2A2_HUMAN with the residue 295 substituted with Nitrated tyrosine" [UniProtKB:P16615] xref: UniProtKB:P16615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:B0063649 name: AT8A2_HUMAN-Phosphothreonine5 def: "Protein AT8A2_HUMAN with the residue 5 substituted with Phosphothreonine" [UniProtKB:Q9NTI2] comment: By similarity xref: UniProtKB:Q9NTI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058925 ! AT8A2_HUMAN [Term] id: CCO:B0063650 name: ATF1_HUMAN-Phosphoserine63 def: "Protein ATF1_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:P18846] comment: by CaMK1; xref: UniProtKB:P18846 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055105 ! ATF1_HUMAN [Term] id: CCO:B0063651 name: ATF2_HUMAN-Phosphothreonine69 def: "Protein ATF2_HUMAN with the residue 69 substituted with Phosphothreonine" [UniProtKB:P15336] comment: by MAPK14; xref: UniProtKB:P15336 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018367 ! ATF2_HUMAN [Term] id: CCO:B0063652 name: ATF2_HUMAN-Phosphothreonine71 def: "Protein ATF2_HUMAN with the residue 71 substituted with Phosphothreonine" [UniProtKB:P15336] comment: by MAPK14; xref: UniProtKB:P15336 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0018367 ! ATF2_HUMAN [Term] id: CCO:B0063653 name: ATF2_HUMAN-Phosphoserine112 def: "Protein ATF2_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:P15336] xref: UniProtKB:P15336 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018367 ! ATF2_HUMAN [Term] id: CCO:B0063654 name: ATF2_HUMAN-Phosphoserine328 def: "Protein ATF2_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P15336] xref: UniProtKB:P15336 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018367 ! ATF2_HUMAN [Term] id: CCO:B0063655 name: ATN1_HUMAN-Phosphothreonine646 def: "Protein ATN1_HUMAN with the residue 646 substituted with Phosphothreonine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0063656 name: ATN1_HUMAN-Phosphotyrosine729 def: "Protein ATN1_HUMAN with the residue 729 substituted with Phosphotyrosine" [UniProtKB:P54259] xref: UniProtKB:P54259 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:B0063657 name: ATP7A_HUMAN-Phosphoserine353 def: "Protein ATP7A_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q04656] comment: By similarity xref: UniProtKB:Q04656 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055732 ! ATP7A_HUMAN [Term] id: CCO:B0063658 name: ATP7A_HUMAN-Phosphoserine357 def: "Protein ATP7A_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q04656] comment: By similarity xref: UniProtKB:Q04656 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055732 ! ATP7A_HUMAN [Term] id: CCO:B0063659 name: ATRIP_HUMAN-Phosphoserine224 def: "Protein ATRIP_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:Q8WXE1] xref: UniProtKB:Q8WXE1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002009 ! ATRIP_HUMAN [Term] id: CCO:B0063660 name: ATR_HUMAN-Phosphothreonine1989 def: "Protein ATR_HUMAN with the residue 1989 substituted with Phosphothreonine" [UniProtKB:Q13535] xref: UniProtKB:Q13535 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001756 ! ATR_HUMAN [Term] id: CCO:B0063661 name: ATX1_HUMAN-Phosphoserine238 def: "Protein ATX1_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:P54253] xref: UniProtKB:P54253 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001806 ! poly(U) binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005507 ! poly(rG) binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005879 ! protein self-association relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0001636 ! nuclear RNA export factor complex relationship: located_in CCO:C0001640 ! nuclear inclusion body relationship: transformation_of CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:B0063662 name: ATX1_HUMAN-Phosphoserine253 def: "Protein ATX1_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:P54253] xref: UniProtKB:P54253 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:B0063663 name: ATX2_HUMAN-Phosphoserine466 def: "Protein ATX2_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063664 name: ATX2_HUMAN-Phosphoserine554 def: "Protein ATX2_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063665 name: ATX2_HUMAN-Phosphoserine558 def: "Protein ATX2_HUMAN with the residue 558 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063666 name: ATX2_HUMAN-Phosphoserine644 def: "Protein ATX2_HUMAN with the residue 644 substituted with Phosphoserine" [UniProtKB:Q99700] comment: By similarity xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063667 name: ATX2_HUMAN-Phosphoserine667 def: "Protein ATX2_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063668 name: ATX2_HUMAN-Phosphoserine684 def: "Protein ATX2_HUMAN with the residue 684 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063669 name: ATX2_HUMAN-Phosphothreonine741 def: "Protein ATX2_HUMAN with the residue 741 substituted with Phosphothreonine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063670 name: ATX2_HUMAN-Phosphoserine744 def: "Protein ATX2_HUMAN with the residue 744 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063671 name: ATX2_HUMAN-Phosphothreonine771 def: "Protein ATX2_HUMAN with the residue 771 substituted with Phosphothreonine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063672 name: ATX2_HUMAN-Phosphoserine772 def: "Protein ATX2_HUMAN with the residue 772 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063673 name: ATX2_HUMAN-Phosphoserine776 def: "Protein ATX2_HUMAN with the residue 776 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063674 name: ATX2_HUMAN-Phosphoserine784 def: "Protein ATX2_HUMAN with the residue 784 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063675 name: ATX2_HUMAN-Phosphoserine828 def: "Protein ATX2_HUMAN with the residue 828 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063676 name: ATX2_HUMAN-Phosphoserine839 def: "Protein ATX2_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000410 ! polysome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002047 ! stress granule relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063677 name: ATX2_HUMAN-Phosphoserine849 def: "Protein ATX2_HUMAN with the residue 849 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063678 name: ATX2_HUMAN-Phosphoserine857 def: "Protein ATX2_HUMAN with the residue 857 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063679 name: ATX2_HUMAN-Phosphoserine861 def: "Protein ATX2_HUMAN with the residue 861 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063680 name: ATX2_HUMAN-Phosphoserine863 def: "Protein ATX2_HUMAN with the residue 863 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063681 name: ATX2_HUMAN-Phosphoserine865 def: "Protein ATX2_HUMAN with the residue 865 substituted with Phosphoserine" [UniProtKB:Q99700] comment: By similarity xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063682 name: ATX2_HUMAN-Phosphoserine888 def: "Protein ATX2_HUMAN with the residue 888 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063683 name: ATX2_HUMAN-Phosphoserine889 def: "Protein ATX2_HUMAN with the residue 889 substituted with Phosphoserine" [UniProtKB:Q99700] xref: UniProtKB:Q99700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:B0063684 name: AURKB_HUMAN-Phosphothreonine35 def: "Protein AURKB_HUMAN with the residue 35 substituted with Phosphothreonine" [UniProtKB:Q96GD4] xref: UniProtKB:Q96GD4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:B0063685 name: AVEN_HUMAN-Phosphoserine94 def: "Protein AVEN_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q9NQS1] xref: UniProtKB:Q9NQS1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058871 ! AVEN_HUMAN [Term] id: CCO:B0063686 name: AXN2_HUMAN-Phosphoserine630 def: "Protein AXN2_HUMAN with the residue 630 substituted with Phosphoserine" [UniProtKB:Q9Y2T1] xref: UniProtKB:Q9Y2T1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059315 ! AXN2_HUMAN [Term] id: CCO:B0063687 name: AXN2_HUMAN-Phosphoserine639 def: "Protein AXN2_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:Q9Y2T1] xref: UniProtKB:Q9Y2T1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059315 ! AXN2_HUMAN [Term] id: CCO:B0063688 name: AXN2_HUMAN-Phosphothreonine640 def: "Protein AXN2_HUMAN with the residue 640 substituted with Phosphothreonine" [UniProtKB:Q9Y2T1] xref: UniProtKB:Q9Y2T1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059315 ! AXN2_HUMAN [Term] id: CCO:B0063689 name: B2L14_HUMAN-Phosphoserine152 def: "Protein B2L14_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q9BZR8] xref: UniProtKB:Q9BZR8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058605 ! B2L14_HUMAN [Term] id: CCO:B0063690 name: BACH1_HUMAN-Phosphoserine196 def: "Protein BACH1_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:O14867] xref: UniProtKB:O14867 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054384 ! BACH1_HUMAN [Term] id: CCO:B0063691 name: BACH1_HUMAN-Phosphoserine445 def: "Protein BACH1_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:O14867] xref: UniProtKB:O14867 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054384 ! BACH1_HUMAN [Term] id: CCO:B0063692 name: BAG3_HUMAN-Phosphoserine134 def: "Protein BAG3_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063693 name: BAG3_HUMAN-Phosphoserine136 def: "Protein BAG3_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063694 name: BAG3_HUMAN-Phosphoserine171 def: "Protein BAG3_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063695 name: BAG3_HUMAN-Phosphoserine173 def: "Protein BAG3_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063696 name: BAG3_HUMAN-Phosphoserine194 def: "Protein BAG3_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063697 name: BAG3_HUMAN-Phosphotyrosine240 def: "Protein BAG3_HUMAN with the residue 240 substituted with Phosphotyrosine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063698 name: BAG3_HUMAN-Phosphotyrosine247 def: "Protein BAG3_HUMAN with the residue 247 substituted with Phosphotyrosine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063699 name: BAG3_HUMAN-Phosphoserine275 def: "Protein BAG3_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063700 name: BAG3_HUMAN-Phosphoserine279 def: "Protein BAG3_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063701 name: BAG3_HUMAN-Phosphothreonine285 def: "Protein BAG3_HUMAN with the residue 285 substituted with Phosphothreonine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004345 ! Hsp70/Hsc70 protein regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063702 name: BAG3_HUMAN-Phosphoserine289 def: "Protein BAG3_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063703 name: BAG3_HUMAN-Phosphoserine291 def: "Protein BAG3_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063704 name: BAG3_HUMAN-Phosphoserine377 def: "Protein BAG3_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:O95817] xref: UniProtKB:O95817 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:B0063705 name: BAI1_HUMAN-Phosphoserine1278 def: "Protein BAI1_HUMAN with the residue 1278 substituted with Phosphoserine" [UniProtKB:O14514] comment: By similarity xref: UniProtKB:O14514 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054348 ! BAI1_HUMAN [Term] id: CCO:B0063706 name: BAI1_HUMAN-Phosphoserine1469 def: "Protein BAI1_HUMAN with the residue 1469 substituted with Phosphoserine" [UniProtKB:O14514] comment: By similarity xref: UniProtKB:O14514 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054348 ! BAI1_HUMAN [Term] id: CCO:B0063707 name: BAI2_HUMAN-Phosphotyrosine1339 def: "Protein BAI2_HUMAN with the residue 1339 substituted with Phosphotyrosine" [UniProtKB:O60241] comment: By similarity xref: UniProtKB:O60241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021210 ! BAI2_HUMAN [Term] id: CCO:B0063708 name: BAI3_HUMAN-Phosphoserine1220 def: "Protein BAI3_HUMAN with the residue 1220 substituted with Phosphoserine" [UniProtKB:O60242] comment: By similarity xref: UniProtKB:O60242 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003198 ! brain-specific angiogenesis inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054536 ! BAI3_HUMAN [Term] id: CCO:B0063709 name: BAI3_HUMAN-Phosphoserine1411 def: "Protein BAI3_HUMAN with the residue 1411 substituted with Phosphoserine" [UniProtKB:O60242] comment: By similarity xref: UniProtKB:O60242 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054536 ! BAI3_HUMAN [Term] id: CCO:B0063710 name: BAIP2_HUMAN-Phosphotyrosine157 def: "Protein BAIP2_HUMAN with the residue 157 substituted with Phosphotyrosine" [UniProtKB:Q9UQB8] comment: By similarity xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063711 name: BAIP2_HUMAN-Phosphothreonine296 def: "Protein BAIP2_HUMAN with the residue 296 substituted with Phosphothreonine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063712 name: BAIP2_HUMAN-Phosphotyrosine310 def: "Protein BAIP2_HUMAN with the residue 310 substituted with Phosphotyrosine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063713 name: BAIP2_HUMAN-Phosphoserine323 def: "Protein BAIP2_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063714 name: BAIP2_HUMAN-Phosphoserine325 def: "Protein BAIP2_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063715 name: BAIP2_HUMAN-Phosphotyrosine337 def: "Protein BAIP2_HUMAN with the residue 337 substituted with Phosphotyrosine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063716 name: BAIP2_HUMAN-Phosphoserine346 def: "Protein BAIP2_HUMAN with the residue 346 substituted with Phosphoserine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063717 name: BAIP2_HUMAN-Phosphothreonine348 def: "Protein BAIP2_HUMAN with the residue 348 substituted with Phosphothreonine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063718 name: BAIP2_HUMAN-Phosphoserine366 def: "Protein BAIP2_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063719 name: BAIP2_HUMAN-Phosphoserine452 def: "Protein BAIP2_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:Q9UQB8] comment: By similarity xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063720 name: BAIP2_HUMAN-Phosphoserine453 def: "Protein BAIP2_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q9UQB8] comment: By similarity xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063721 name: BAIP2_HUMAN-Phosphoserine454 def: "Protein BAIP2_HUMAN with the residue 454 substituted with Phosphoserine" [UniProtKB:Q9UQB8] comment: By similarity xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063722 name: BAIP2_HUMAN-Phosphotyrosine491 def: "Protein BAIP2_HUMAN with the residue 491 substituted with Phosphotyrosine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063723 name: BAIP2_HUMAN-Phosphotyrosine505 def: "Protein BAIP2_HUMAN with the residue 505 substituted with Phosphotyrosine" [UniProtKB:Q9UQB8] xref: UniProtKB:Q9UQB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:B0063724 name: BAP1_HUMAN-Phosphoserine395 def: "Protein BAP1_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q92560] xref: UniProtKB:Q92560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058063 ! BAP1_HUMAN [Term] id: CCO:B0063725 name: BAP1_HUMAN-Phosphothreonine487 def: "Protein BAP1_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:Q92560] xref: UniProtKB:Q92560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058063 ! BAP1_HUMAN [Term] id: CCO:B0063726 name: BAP1_HUMAN-Phosphoserine489 def: "Protein BAP1_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q92560] xref: UniProtKB:Q92560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058063 ! BAP1_HUMAN [Term] id: CCO:B0063727 name: BAP1_HUMAN-Phosphoserine583 def: "Protein BAP1_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:Q92560] xref: UniProtKB:Q92560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058063 ! BAP1_HUMAN [Term] id: CCO:B0063728 name: BAP1_HUMAN-Phosphoserine592 def: "Protein BAP1_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:Q92560] xref: UniProtKB:Q92560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058063 ! BAP1_HUMAN [Term] id: CCO:B0063729 name: BAP1_HUMAN-Phosphoserine597 def: "Protein BAP1_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:Q92560] xref: UniProtKB:Q92560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058063 ! BAP1_HUMAN [Term] id: CCO:B0063730 name: BARD1_HUMAN-Phosphoserine148 def: "Protein BARD1_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q99728] xref: UniProtKB:Q99728 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002086 ! BARD1_HUMAN [Term] id: CCO:B0063731 name: BARD1_HUMAN-Phosphoserine391 def: "Protein BARD1_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q99728] xref: UniProtKB:Q99728 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002086 ! BARD1_HUMAN [Term] id: CCO:B0063732 name: BARD1_HUMAN-Phosphothreonine394 def: "Protein BARD1_HUMAN with the residue 394 substituted with Phosphothreonine" [UniProtKB:Q99728] xref: UniProtKB:Q99728 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002086 ! BARD1_HUMAN [Term] id: CCO:B0063733 name: BASI_HUMAN-Phosphoserine362 def: "Protein BASI_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:P35613] xref: UniProtKB:P35613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_function CCO:F0001662 ! mannose binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0055296 ! BASI_HUMAN [Term] id: CCO:B0063734 name: BASI_HUMAN-Phosphoserine368 def: "Protein BASI_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:P35613] xref: UniProtKB:P35613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055296 ! BASI_HUMAN [Term] id: CCO:B0063735 name: BAT2_HUMAN-Phosphoserine383 def: "Protein BAT2_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063736 name: BAT2_HUMAN-Phosphoserine766 def: "Protein BAT2_HUMAN with the residue 766 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063737 name: BAT2_HUMAN-Phosphothreonine997 def: "Protein BAT2_HUMAN with the residue 997 substituted with Phosphothreonine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063738 name: BAT2_HUMAN-Phosphoserine1085 def: "Protein BAT2_HUMAN with the residue 1085 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063739 name: BAT2_HUMAN-Phosphothreonine1087 def: "Protein BAT2_HUMAN with the residue 1087 substituted with Phosphothreonine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063740 name: BAT2_HUMAN-Phosphotyrosine1094 def: "Protein BAT2_HUMAN with the residue 1094 substituted with Phosphotyrosine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063741 name: BAT2_HUMAN-Phosphoserine1147 def: "Protein BAT2_HUMAN with the residue 1147 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063742 name: BAT2_HUMAN-Phosphoserine1306 def: "Protein BAT2_HUMAN with the residue 1306 substituted with Phosphoserine" [UniProtKB:P48634] xref: UniProtKB:P48634 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:B0063743 name: BAZ1A_HUMAN-Phosphotyrosine606 def: "Protein BAZ1A_HUMAN with the residue 606 substituted with Phosphotyrosine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063744 name: BAZ1A_HUMAN-Phosphoserine1339 def: "Protein BAZ1A_HUMAN with the residue 1339 substituted with Phosphoserine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063745 name: BAZ1A_HUMAN-Phosphoserine1353 def: "Protein BAZ1A_HUMAN with the residue 1353 substituted with Phosphoserine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063746 name: BAZ1A_HUMAN-Phosphoserine1363 def: "Protein BAZ1A_HUMAN with the residue 1363 substituted with Phosphoserine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063747 name: BAZ1A_HUMAN-Phosphothreonine1367 def: "Protein BAZ1A_HUMAN with the residue 1367 substituted with Phosphothreonine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063748 name: BAZ1A_HUMAN-Phosphoserine1371 def: "Protein BAZ1A_HUMAN with the residue 1371 substituted with Phosphoserine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063749 name: BAZ1A_HUMAN-Phosphoserine1402 def: "Protein BAZ1A_HUMAN with the residue 1402 substituted with Phosphoserine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063750 name: BAZ1A_HUMAN-Phosphoserine1413 def: "Protein BAZ1A_HUMAN with the residue 1413 substituted with Phosphoserine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063751 name: BAZ1A_HUMAN-Phosphoserine1417 def: "Protein BAZ1A_HUMAN with the residue 1417 substituted with Phosphoserine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063752 name: BAZ1A_HUMAN-Phosphothreonine1547 def: "Protein BAZ1A_HUMAN with the residue 1547 substituted with Phosphothreonine" [UniProtKB:Q9NRL2] xref: UniProtKB:Q9NRL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058901 ! BAZ1A_HUMAN [Term] id: CCO:B0063753 name: BAZ1B_HUMAN-Phosphoserine161 def: "Protein BAZ1B_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q9UIG0] comment: By similarity xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063754 name: BAZ1B_HUMAN-Phosphoserine167 def: "Protein BAZ1B_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063755 name: BAZ1B_HUMAN-Phosphoserine189 def: "Protein BAZ1B_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063756 name: BAZ1B_HUMAN-Phosphoserine330 def: "Protein BAZ1B_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063757 name: BAZ1B_HUMAN-Phosphoserine345 def: "Protein BAZ1B_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063758 name: BAZ1B_HUMAN-Phosphoserine347 def: "Protein BAZ1B_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002171 ! centromeric heterochromatin relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063759 name: BAZ1B_HUMAN-Phosphoserine349 def: "Protein BAZ1B_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063760 name: BAZ1B_HUMAN-Phosphoserine361 def: "Protein BAZ1B_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063761 name: BAZ1B_HUMAN-Phosphoserine374 def: "Protein BAZ1B_HUMAN with the residue 374 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063762 name: BAZ1B_HUMAN-Phosphoserine699 def: "Protein BAZ1B_HUMAN with the residue 699 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063763 name: BAZ1B_HUMAN-Phosphoserine705 def: "Protein BAZ1B_HUMAN with the residue 705 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063764 name: BAZ1B_HUMAN-Phosphoserine708 def: "Protein BAZ1B_HUMAN with the residue 708 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063765 name: BAZ1B_HUMAN-Phosphoserine716 def: "Protein BAZ1B_HUMAN with the residue 716 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063766 name: BAZ1B_HUMAN-Phosphoserine947 def: "Protein BAZ1B_HUMAN with the residue 947 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063767 name: BAZ1B_HUMAN-Phosphoserine1147 def: "Protein BAZ1B_HUMAN with the residue 1147 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063768 name: BAZ1B_HUMAN-Phosphoserine1315 def: "Protein BAZ1B_HUMAN with the residue 1315 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063769 name: BAZ1B_HUMAN-Phosphoserine1342 def: "Protein BAZ1B_HUMAN with the residue 1342 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063770 name: BAZ1B_HUMAN-Phosphoserine1468 def: "Protein BAZ1B_HUMAN with the residue 1468 substituted with Phosphoserine" [UniProtKB:Q9UIG0] xref: UniProtKB:Q9UIG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:B0063771 name: BAZ2A_HUMAN-Phosphoserine469 def: "Protein BAZ2A_HUMAN with the residue 469 substituted with Phosphoserine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063772 name: BAZ2A_HUMAN-Phosphothreonine521 def: "Protein BAZ2A_HUMAN with the residue 521 substituted with Phosphothreonine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000321 ! nucleolus organizer region relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063773 name: BAZ2A_HUMAN-Phosphoserine1024 def: "Protein BAZ2A_HUMAN with the residue 1024 substituted with Phosphoserine" [UniProtKB:Q9UIF9] comment: By similarity xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063774 name: BAZ2A_HUMAN-Phosphoserine1370 def: "Protein BAZ2A_HUMAN with the residue 1370 substituted with Phosphoserine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063775 name: BAZ2A_HUMAN-Phosphoserine1532 def: "Protein BAZ2A_HUMAN with the residue 1532 substituted with Phosphoserine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063776 name: BAZ2A_HUMAN-Phosphoserine1720 def: "Protein BAZ2A_HUMAN with the residue 1720 substituted with Phosphoserine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063777 name: BAZ2A_HUMAN-Phosphoserine1743 def: "Protein BAZ2A_HUMAN with the residue 1743 substituted with Phosphoserine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063778 name: BAZ2A_HUMAN-Phosphoserine1751 def: "Protein BAZ2A_HUMAN with the residue 1751 substituted with Phosphoserine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063779 name: BAZ2A_HUMAN-Phosphoserine1756 def: "Protein BAZ2A_HUMAN with the residue 1756 substituted with Phosphoserine" [UniProtKB:Q9UIF9] xref: UniProtKB:Q9UIF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:B0063780 name: BAZ2B_HUMAN-Phosphothreonine1087 def: "Protein BAZ2B_HUMAN with the residue 1087 substituted with Phosphothreonine" [UniProtKB:Q9UIF8] xref: UniProtKB:Q9UIF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059159 ! BAZ2B_HUMAN [Term] id: CCO:B0063781 name: BBX_HUMAN-Phosphoserine479 def: "Protein BBX_HUMAN with the residue 479 substituted with Phosphoserine" [UniProtKB:Q8WY36] xref: UniProtKB:Q8WY36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058038 ! BBX_HUMAN [Term] id: CCO:B0063782 name: BBX_HUMAN-Phosphoserine485 def: "Protein BBX_HUMAN with the residue 485 substituted with Phosphoserine" [UniProtKB:Q8WY36] xref: UniProtKB:Q8WY36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058038 ! BBX_HUMAN [Term] id: CCO:B0063783 name: BBX_HUMAN-Phosphothreonine809 def: "Protein BBX_HUMAN with the residue 809 substituted with Phosphothreonine" [UniProtKB:Q8WY36] xref: UniProtKB:Q8WY36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058038 ! BBX_HUMAN [Term] id: CCO:B0063784 name: BBX_HUMAN-Phosphoserine822 def: "Protein BBX_HUMAN with the residue 822 substituted with Phosphoserine" [UniProtKB:Q8WY36] xref: UniProtKB:Q8WY36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058038 ! BBX_HUMAN [Term] id: CCO:B0063785 name: BCAR1_HUMAN-Phosphoserine134 def: "Protein BCAR1_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0063786 name: BCAR1_HUMAN-Phosphothreonine269 def: "Protein BCAR1_HUMAN with the residue 269 substituted with Phosphothreonine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0063787 name: BCAR1_HUMAN-Phosphoserine292 def: "Protein BCAR1_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:P56945] xref: UniProtKB:P56945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:B0063788 name: BCKD_HUMAN-Phosphoserine31 def: "Protein BCKD_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:O14874] comment: By similarity xref: UniProtKB:O14874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054385 ! BCKD_HUMAN [Term] id: CCO:B0063789 name: BCKD_HUMAN-Phosphoserine33 def: "Protein BCKD_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:O14874] xref: UniProtKB:O14874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054385 ! BCKD_HUMAN [Term] id: CCO:B0063790 name: BCKD_HUMAN-Phosphothreonine35 def: "Protein BCKD_HUMAN with the residue 35 substituted with Phosphothreonine" [UniProtKB:O14874] comment: By similarity xref: UniProtKB:O14874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054385 ! BCKD_HUMAN [Term] id: CCO:B0063791 name: BCKD_HUMAN-Phosphoserine52 def: "Protein BCKD_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:O14874] comment: by autocatalysis; By similarity xref: UniProtKB:O14874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000029 ! two-component sensor activity relationship: has_function CCO:F0001044 ! protein histidine kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups relationship: has_function CCO:F0008313 ! [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000497 ! mitochondrial alpha-ketoglutarate dehydrogenase complex relationship: transformation_of CCO:B0054385 ! BCKD_HUMAN [Term] id: CCO:B0063792 name: BCL7A_HUMAN-Phosphoserine154 def: "Protein BCL7A_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q4VC05] xref: UniProtKB:Q4VC05 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056331 ! BCL7A_HUMAN [Term] id: CCO:B0063793 name: BCL7A_HUMAN-Phosphoserine186 def: "Protein BCL7A_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:Q4VC05] xref: UniProtKB:Q4VC05 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056331 ! BCL7A_HUMAN [Term] id: CCO:B0063794 name: BCL7A_HUMAN-Phosphoserine203 def: "Protein BCL7A_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q4VC05] xref: UniProtKB:Q4VC05 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0056331 ! BCL7A_HUMAN [Term] id: CCO:B0063795 name: BCL7A_HUMAN-Phosphoserine207 def: "Protein BCL7A_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:Q4VC05] xref: UniProtKB:Q4VC05 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056331 ! BCL7A_HUMAN [Term] id: CCO:B0063796 name: BCL9L_HUMAN-Phosphoserine21 def: "Protein BCL9L_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063797 name: BCL9L_HUMAN-Phosphoserine25 def: "Protein BCL9L_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063798 name: BCL9L_HUMAN-N6-acetyllysine36 def: "Protein BCL9L_HUMAN with the residue 36 substituted with N6-acetyllysine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063799 name: BCL9L_HUMAN-Phosphoserine88 def: "Protein BCL9L_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063800 name: BCL9L_HUMAN-Phosphoserine118 def: "Protein BCL9L_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063801 name: BCL9L_HUMAN-Phosphoserine750 def: "Protein BCL9L_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063802 name: BCL9L_HUMAN-Phosphoserine813 def: "Protein BCL9L_HUMAN with the residue 813 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063803 name: BCL9L_HUMAN-Phosphoserine915 def: "Protein BCL9L_HUMAN with the residue 915 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063804 name: BCL9L_HUMAN-Phosphoserine954 def: "Protein BCL9L_HUMAN with the residue 954 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063805 name: BCL9L_HUMAN-Phosphothreonine957 def: "Protein BCL9L_HUMAN with the residue 957 substituted with Phosphothreonine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063806 name: BCL9L_HUMAN-Phosphoserine987 def: "Protein BCL9L_HUMAN with the residue 987 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063807 name: BCL9L_HUMAN-Phosphoserine991 def: "Protein BCL9L_HUMAN with the residue 991 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063808 name: BCL9L_HUMAN-Phosphoserine997 def: "Protein BCL9L_HUMAN with the residue 997 substituted with Phosphoserine" [UniProtKB:Q86UU0] comment: By similarity xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063809 name: BCL9L_HUMAN-Phosphoserine999 def: "Protein BCL9L_HUMAN with the residue 999 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063810 name: BCL9L_HUMAN-Phosphoserine1004 def: "Protein BCL9L_HUMAN with the residue 1004 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063811 name: BCL9L_HUMAN-Phosphoserine1010 def: "Protein BCL9L_HUMAN with the residue 1010 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063812 name: BCL9L_HUMAN-Phosphoserine1017 def: "Protein BCL9L_HUMAN with the residue 1017 substituted with Phosphoserine" [UniProtKB:Q86UU0] xref: UniProtKB:Q86UU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057256 ! BCL9L_HUMAN [Term] id: CCO:B0063813 name: BCLF1_HUMAN-Phosphoserine102 def: "Protein BCLF1_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063814 name: BCLF1_HUMAN-Phosphoserine104 def: "Protein BCLF1_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063815 name: BCLF1_HUMAN-Phosphoserine119 def: "Protein BCLF1_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063816 name: BCLF1_HUMAN-Phosphoserine148 def: "Protein BCLF1_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063817 name: BCLF1_HUMAN-Phosphoserine151 def: "Protein BCLF1_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063818 name: BCLF1_HUMAN-Phosphoserine153 def: "Protein BCLF1_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063819 name: BCLF1_HUMAN-Phosphoserine161 def: "Protein BCLF1_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063820 name: BCLF1_HUMAN-Phosphoserine177 def: "Protein BCLF1_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063821 name: BCLF1_HUMAN-Phosphoserine181 def: "Protein BCLF1_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063822 name: BCLF1_HUMAN-Phosphoserine183 def: "Protein BCLF1_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063823 name: BCLF1_HUMAN-Phosphoserine198 def: "Protein BCLF1_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063824 name: BCLF1_HUMAN-Phosphoserine217 def: "Protein BCLF1_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063825 name: BCLF1_HUMAN-Phosphoserine222 def: "Protein BCLF1_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063826 name: BCLF1_HUMAN-Phosphoserine264 def: "Protein BCLF1_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063827 name: BCLF1_HUMAN-Phosphoserine268 def: "Protein BCLF1_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063828 name: BCLF1_HUMAN-Phosphoserine276 def: "Protein BCLF1_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063829 name: BCLF1_HUMAN-Phosphoserine281 def: "Protein BCLF1_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063830 name: BCLF1_HUMAN-Phosphotyrosine284 def: "Protein BCLF1_HUMAN with the residue 284 substituted with Phosphotyrosine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063831 name: BCLF1_HUMAN-Phosphoserine285 def: "Protein BCLF1_HUMAN with the residue 285 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063832 name: BCLF1_HUMAN-Phosphoserine287 def: "Protein BCLF1_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063833 name: BCLF1_HUMAN-Phosphoserine290 def: "Protein BCLF1_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063834 name: BCLF1_HUMAN-Phosphoserine297 def: "Protein BCLF1_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063835 name: BCLF1_HUMAN-Phosphoserine315 def: "Protein BCLF1_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063836 name: BCLF1_HUMAN-Phosphoserine319 def: "Protein BCLF1_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063837 name: BCLF1_HUMAN-Phosphoserine320 def: "Protein BCLF1_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063838 name: BCLF1_HUMAN-Phosphothreonine341 def: "Protein BCLF1_HUMAN with the residue 341 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063839 name: BCLF1_HUMAN-Phosphoserine385 def: "Protein BCLF1_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063840 name: BCLF1_HUMAN-Phosphoserine389 def: "Protein BCLF1_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063841 name: BCLF1_HUMAN-Phosphoserine397 def: "Protein BCLF1_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063842 name: BCLF1_HUMAN-Phosphothreonine402 def: "Protein BCLF1_HUMAN with the residue 402 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063843 name: BCLF1_HUMAN-Phosphothreonine405 def: "Protein BCLF1_HUMAN with the residue 405 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063844 name: BCLF1_HUMAN-Phosphotyrosine408 def: "Protein BCLF1_HUMAN with the residue 408 substituted with Phosphotyrosine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063845 name: BCLF1_HUMAN-Phosphoserine443 def: "Protein BCLF1_HUMAN with the residue 443 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063846 name: BCLF1_HUMAN-Phosphoserine450 def: "Protein BCLF1_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063847 name: BCLF1_HUMAN-Phosphothreonine489 def: "Protein BCLF1_HUMAN with the residue 489 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063848 name: BCLF1_HUMAN-Phosphothreonine494 def: "Protein BCLF1_HUMAN with the residue 494 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063849 name: BCLF1_HUMAN-Phosphoserine496 def: "Protein BCLF1_HUMAN with the residue 496 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063850 name: BCLF1_HUMAN-Phosphoserine502 def: "Protein BCLF1_HUMAN with the residue 502 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063851 name: BCLF1_HUMAN-Phosphotyrosine511 def: "Protein BCLF1_HUMAN with the residue 511 substituted with Phosphotyrosine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063852 name: BCLF1_HUMAN-Phosphoserine512 def: "Protein BCLF1_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063853 name: BCLF1_HUMAN-Phosphoserine525 def: "Protein BCLF1_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063854 name: BCLF1_HUMAN-Phosphothreonine526 def: "Protein BCLF1_HUMAN with the residue 526 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063855 name: BCLF1_HUMAN-Phosphoserine531 def: "Protein BCLF1_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063856 name: BCLF1_HUMAN-Phosphoserine578 def: "Protein BCLF1_HUMAN with the residue 578 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063857 name: BCLF1_HUMAN-Phosphoserine648 def: "Protein BCLF1_HUMAN with the residue 648 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063858 name: BCLF1_HUMAN-Phosphoserine658 def: "Protein BCLF1_HUMAN with the residue 658 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063859 name: BCLF1_HUMAN-Phosphothreonine661 def: "Protein BCLF1_HUMAN with the residue 661 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063860 name: BCLF1_HUMAN-Phosphoserine690 def: "Protein BCLF1_HUMAN with the residue 690 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063861 name: BCLF1_HUMAN-Phosphoserine711 def: "Protein BCLF1_HUMAN with the residue 711 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063862 name: BCLF1_HUMAN-Phosphoserine720 def: "Protein BCLF1_HUMAN with the residue 720 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063863 name: BCLF1_HUMAN-Phosphoserine760 def: "Protein BCLF1_HUMAN with the residue 760 substituted with Phosphoserine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063864 name: BCLF1_HUMAN-Phosphothreonine840 def: "Protein BCLF1_HUMAN with the residue 840 substituted with Phosphothreonine" [UniProtKB:Q9NYF8] xref: UniProtKB:Q9NYF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058962 ! BCLF1_HUMAN [Term] id: CCO:B0063865 name: BCLW_HUMAN-Phosphoserine192 def: "Protein BCLW_HUMAN with the residue 192 substituted with Phosphoserine" [UniProtKB:Q92843] xref: UniProtKB:Q92843 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: transformation_of CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:B0063866 name: BCOR_HUMAN-Phosphoserine423 def: "Protein BCOR_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:Q6W2J9] xref: UniProtKB:Q6W2J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056966 ! BCOR_HUMAN [Term] id: CCO:B0063867 name: BCOR_HUMAN-Phosphoserine469 def: "Protein BCOR_HUMAN with the residue 469 substituted with Phosphoserine" [UniProtKB:Q6W2J9] xref: UniProtKB:Q6W2J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056966 ! BCOR_HUMAN [Term] id: CCO:B0063868 name: BCOR_HUMAN-Phosphoserine473 def: "Protein BCOR_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:Q6W2J9] xref: UniProtKB:Q6W2J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056966 ! BCOR_HUMAN [Term] id: CCO:B0063869 name: BCOR_HUMAN-Phosphoserine480 def: "Protein BCOR_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:Q6W2J9] xref: UniProtKB:Q6W2J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056966 ! BCOR_HUMAN [Term] id: CCO:B0063870 name: BCOR_HUMAN-Phosphoserine1142 def: "Protein BCOR_HUMAN with the residue 1142 substituted with Phosphoserine" [UniProtKB:Q6W2J9] comment: By similarity xref: UniProtKB:Q6W2J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056966 ! BCOR_HUMAN [Term] id: CCO:B0063871 name: BCOR_HUMAN-Phosphoserine1410 def: "Protein BCOR_HUMAN with the residue 1410 substituted with Phosphoserine" [UniProtKB:Q6W2J9] xref: UniProtKB:Q6W2J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056966 ! BCOR_HUMAN [Term] id: CCO:B0063872 name: BDP1_HUMAN-Phosphoserine2196 def: "Protein BDP1_HUMAN with the residue 2196 substituted with Phosphoserine" [UniProtKB:A6H8Y1] xref: UniProtKB:A6H8Y1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053780 ! BDP1_HUMAN [Term] id: CCO:B0063873 name: BFAR_HUMAN-Phosphoserine376 def: "Protein BFAR_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q9NZS9] xref: UniProtKB:Q9NZS9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059015 ! BFAR_HUMAN [Term] id: CCO:B0063874 name: BGH3_HUMAN-4-carboxyglutamate108 def: "Protein BGH3_HUMAN with the residue 108 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063875 name: BGH3_HUMAN-4-carboxyglutamate126 def: "Protein BGH3_HUMAN with the residue 126 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063876 name: BGH3_HUMAN-4-carboxyglutamate131 def: "Protein BGH3_HUMAN with the residue 131 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000237 ! extracellular space relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063877 name: BGH3_HUMAN-4-carboxyglutamate133 def: "Protein BGH3_HUMAN with the residue 133 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063878 name: BGH3_HUMAN-4-carboxyglutamate146 def: "Protein BGH3_HUMAN with the residue 146 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063879 name: BGH3_HUMAN-4-carboxyglutamate154 def: "Protein BGH3_HUMAN with the residue 154 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063880 name: BGH3_HUMAN-4-carboxyglutamate166 def: "Protein BGH3_HUMAN with the residue 166 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063881 name: BGH3_HUMAN-4-carboxyglutamate184 def: "Protein BGH3_HUMAN with the residue 184 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063882 name: BGH3_HUMAN-4-carboxyglutamate248 def: "Protein BGH3_HUMAN with the residue 248 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063883 name: BGH3_HUMAN-4-carboxyglutamate250 def: "Protein BGH3_HUMAN with the residue 250 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063884 name: BGH3_HUMAN-4-carboxyglutamate254 def: "Protein BGH3_HUMAN with the residue 254 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063885 name: BGH3_HUMAN-4-carboxyglutamate270 def: "Protein BGH3_HUMAN with the residue 270 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063886 name: BGH3_HUMAN-4-carboxyglutamate283 def: "Protein BGH3_HUMAN with the residue 283 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063887 name: BGH3_HUMAN-4-carboxyglutamate286 def: "Protein BGH3_HUMAN with the residue 286 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063888 name: BGH3_HUMAN-4-carboxyglutamate291 def: "Protein BGH3_HUMAN with the residue 291 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063889 name: BGH3_HUMAN-4-carboxyglutamate301 def: "Protein BGH3_HUMAN with the residue 301 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063890 name: BGH3_HUMAN-4-carboxyglutamate319 def: "Protein BGH3_HUMAN with the residue 319 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063891 name: BGH3_HUMAN-4-carboxyglutamate328 def: "Protein BGH3_HUMAN with the residue 328 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063892 name: BGH3_HUMAN-4-carboxyglutamate331 def: "Protein BGH3_HUMAN with the residue 331 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063893 name: BGH3_HUMAN-4-carboxyglutamate336 def: "Protein BGH3_HUMAN with the residue 336 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063894 name: BGH3_HUMAN-4-carboxyglutamate529 def: "Protein BGH3_HUMAN with the residue 529 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063895 name: BGH3_HUMAN-4-carboxyglutamate534 def: "Protein BGH3_HUMAN with the residue 534 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063896 name: BGH3_HUMAN-4-carboxyglutamate545 def: "Protein BGH3_HUMAN with the residue 545 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063897 name: BGH3_HUMAN-4-carboxyglutamate554 def: "Protein BGH3_HUMAN with the residue 554 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063898 name: BGH3_HUMAN-4-carboxyglutamate564 def: "Protein BGH3_HUMAN with the residue 564 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063899 name: BGH3_HUMAN-4-carboxyglutamate576 def: "Protein BGH3_HUMAN with the residue 576 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063900 name: BGH3_HUMAN-4-carboxyglutamate598 def: "Protein BGH3_HUMAN with the residue 598 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063901 name: BGH3_HUMAN-4-carboxyglutamate611 def: "Protein BGH3_HUMAN with the residue 611 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063902 name: BGH3_HUMAN-4-carboxyglutamate615 def: "Protein BGH3_HUMAN with the residue 615 substituted with 4-carboxyglutamate" [UniProtKB:Q15582] comment: Potential xref: UniProtKB:Q15582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037751 ! BGH3_HUMAN [Term] id: CCO:B0063903 name: BI2L1_HUMAN-Phosphothreonine248 def: "Protein BI2L1_HUMAN with the residue 248 substituted with Phosphothreonine" [UniProtKB:Q9UHR4] xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063904 name: BI2L1_HUMAN-Phosphothreonine257 def: "Protein BI2L1_HUMAN with the residue 257 substituted with Phosphothreonine" [UniProtKB:Q9UHR4] xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063905 name: BI2L1_HUMAN-Phosphoserine261 def: "Protein BI2L1_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:Q9UHR4] xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063906 name: BI2L1_HUMAN-Phosphoserine281 def: "Protein BI2L1_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q9UHR4] xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063907 name: BI2L1_HUMAN-Phosphoserine329 def: "Protein BI2L1_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q9UHR4] comment: By similarity xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063908 name: BI2L1_HUMAN-Phosphoserine331 def: "Protein BI2L1_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q9UHR4] xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063909 name: BI2L1_HUMAN-Phosphothreonine412 def: "Protein BI2L1_HUMAN with the residue 412 substituted with Phosphothreonine" [UniProtKB:Q9UHR4] xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063910 name: BI2L1_HUMAN-Phosphoserine414 def: "Protein BI2L1_HUMAN with the residue 414 substituted with Phosphoserine" [UniProtKB:Q9UHR4] xref: UniProtKB:Q9UHR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059147 ! BI2L1_HUMAN [Term] id: CCO:B0063911 name: BIG1_HUMAN-Phosphoserine1569 def: "Protein BIG1_HUMAN with the residue 1569 substituted with Phosphoserine" [UniProtKB:Q9Y6D6] xref: UniProtKB:Q9Y6D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024694 ! BIG1_HUMAN [Term] id: CCO:B0063912 name: BIG2_HUMAN-Phosphoserine218 def: "Protein BIG2_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063913 name: BIG2_HUMAN-Phosphoserine227 def: "Protein BIG2_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063914 name: BIG2_HUMAN-Phosphoserine614 def: "Protein BIG2_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063915 name: BIG2_HUMAN-Phosphothreonine616 def: "Protein BIG2_HUMAN with the residue 616 substituted with Phosphothreonine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063916 name: BIG2_HUMAN-Phosphoserine690 def: "Protein BIG2_HUMAN with the residue 690 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063917 name: BIG2_HUMAN-Phosphothreonine691 def: "Protein BIG2_HUMAN with the residue 691 substituted with Phosphothreonine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063918 name: BIG2_HUMAN-Phosphoserine1511 def: "Protein BIG2_HUMAN with the residue 1511 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063919 name: BIG2_HUMAN-Phosphoserine1513 def: "Protein BIG2_HUMAN with the residue 1513 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063920 name: BIG2_HUMAN-Phosphoserine1514 def: "Protein BIG2_HUMAN with the residue 1514 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003516 ! myosin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063921 name: BIG2_HUMAN-Phosphoserine1525 def: "Protein BIG2_HUMAN with the residue 1525 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063922 name: BIG2_HUMAN-Phosphoserine1528 def: "Protein BIG2_HUMAN with the residue 1528 substituted with Phosphoserine" [UniProtKB:Q9Y6D5] xref: UniProtKB:Q9Y6D5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024696 ! BIG2_HUMAN [Term] id: CCO:B0063923 name: BIG3_HUMAN-Phosphoserine1651 def: "Protein BIG3_HUMAN with the residue 1651 substituted with Phosphoserine" [UniProtKB:Q5TH69] comment: By similarity xref: UniProtKB:Q5TH69 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056626 ! BIG3_HUMAN [Term] id: CCO:B0063924 name: BIM_HUMAN-Phosphoserine77 def: "Protein BIM_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:O43521] xref: UniProtKB:O43521 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006003 ! BIM_HUMAN [Term] id: CCO:B0063925 name: BIRC4_HUMAN-Phosphoserine87 def: "Protein BIRC4_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:P98170] comment: by PKB; xref: UniProtKB:P98170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005787 ! caspase inhibitor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:B0063926 name: BIRC4_HUMAN-Phosphotyrosine139 def: "Protein BIRC4_HUMAN with the residue 139 substituted with Phosphotyrosine" [UniProtKB:P98170] xref: UniProtKB:P98170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:B0063927 name: BIRC6_HUMAN-Phosphoserine452 def: "Protein BIRC6_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:Q9NR09] xref: UniProtKB:Q9NR09 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039811 ! BIRC6_HUMAN [Term] id: CCO:B0063928 name: BLM_HUMAN-Phosphoserine48 def: "Protein BLM_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063929 name: BLM_HUMAN-Phosphoserine53 def: "Protein BLM_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063930 name: BLM_HUMAN-Phosphothreonine57 def: "Protein BLM_HUMAN with the residue 57 substituted with Phosphothreonine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063931 name: BLM_HUMAN-Phosphothreonine114 def: "Protein BLM_HUMAN with the residue 114 substituted with Phosphothreonine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063932 name: BLM_HUMAN-Phosphoserine358 def: "Protein BLM_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063933 name: BLM_HUMAN-Phosphoserine1295 def: "Protein BLM_HUMAN with the residue 1295 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063934 name: BLM_HUMAN-Phosphoserine1303 def: "Protein BLM_HUMAN with the residue 1303 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063935 name: BLM_HUMAN-Phosphoserine1310 def: "Protein BLM_HUMAN with the residue 1310 substituted with Phosphoserine" [UniProtKB:P54132] xref: UniProtKB:P54132 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:B0063936 name: BLNK_HUMAN-Phosphotyrosine72 def: "Protein BLNK_HUMAN with the residue 72 substituted with Phosphotyrosine" [UniProtKB:Q8WV28] xref: UniProtKB:Q8WV28 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057988 ! BLNK_HUMAN [Term] id: CCO:B0063937 name: BLNK_HUMAN-Phosphotyrosine84 def: "Protein BLNK_HUMAN with the residue 84 substituted with Phosphotyrosine" [UniProtKB:Q8WV28] xref: UniProtKB:Q8WV28 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057988 ! BLNK_HUMAN [Term] id: CCO:B0063938 name: BLNK_HUMAN-Phosphotyrosine96 def: "Protein BLNK_HUMAN with the residue 96 substituted with Phosphotyrosine" [UniProtKB:Q8WV28] xref: UniProtKB:Q8WV28 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057988 ! BLNK_HUMAN [Term] id: CCO:B0063939 name: BLNK_HUMAN-Phosphotyrosine178 def: "Protein BLNK_HUMAN with the residue 178 substituted with Phosphotyrosine" [UniProtKB:Q8WV28] xref: UniProtKB:Q8WV28 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001378 ! transmembrane receptor protein tyrosine kinase adaptor protein activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057988 ! BLNK_HUMAN [Term] id: CCO:B0063940 name: BLNK_HUMAN-Phosphotyrosine189 def: "Protein BLNK_HUMAN with the residue 189 substituted with Phosphotyrosine" [UniProtKB:Q8WV28] xref: UniProtKB:Q8WV28 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057988 ! BLNK_HUMAN [Term] id: CCO:B0063941 name: BMAL1_HUMAN-N6-acetyllysine538 def: "Protein BMAL1_HUMAN with the residue 538 substituted with N6-acetyllysine" [UniProtKB:O00327] comment: By similarity xref: UniProtKB:O00327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054311 ! BMAL1_HUMAN [Term] id: CCO:B0063942 name: BMI1_HUMAN-Phosphoserine251 def: "Protein BMI1_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:P35226] xref: UniProtKB:P35226 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055279 ! BMI1_HUMAN [Term] id: CCO:B0063943 name: BMI1_HUMAN-Phosphoserine253 def: "Protein BMI1_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:P35226] xref: UniProtKB:P35226 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055279 ! BMI1_HUMAN [Term] id: CCO:B0063944 name: BMI1_HUMAN-Phosphoserine255 def: "Protein BMI1_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:P35226] xref: UniProtKB:P35226 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055279 ! BMI1_HUMAN [Term] id: CCO:B0063945 name: BNC1_HUMAN-Phosphoserine537 def: "Protein BNC1_HUMAN with the residue 537 substituted with Phosphoserine" [UniProtKB:Q01954] xref: UniProtKB:Q01954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0024472 ! BNC1_HUMAN [Term] id: CCO:B0063946 name: BNC1_HUMAN-Phosphoserine541 def: "Protein BNC1_HUMAN with the residue 541 substituted with Phosphoserine" [UniProtKB:Q01954] xref: UniProtKB:Q01954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024472 ! BNC1_HUMAN [Term] id: CCO:B0063947 name: BORA_HUMAN-Phosphoserine183 def: "Protein BORA_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q6PGQ7] xref: UniProtKB:Q6PGQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001914 ! BORA_HUMAN [Term] id: CCO:B0063948 name: BORA_HUMAN-Phosphoserine189 def: "Protein BORA_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q6PGQ7] xref: UniProtKB:Q6PGQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001914 ! BORA_HUMAN [Term] id: CCO:B0063949 name: BORA_HUMAN-Phosphoserine191 def: "Protein BORA_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q6PGQ7] xref: UniProtKB:Q6PGQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001914 ! BORA_HUMAN [Term] id: CCO:B0063950 name: BOREA_HUMAN-Phosphothreonine189 def: "Protein BOREA_HUMAN with the residue 189 substituted with Phosphothreonine" [UniProtKB:Q53HL2] xref: UniProtKB:Q53HL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001839 ! BOREA_HUMAN [Term] id: CCO:B0063951 name: BOREA_HUMAN-Phosphothreonine204 def: "Protein BOREA_HUMAN with the residue 204 substituted with Phosphothreonine" [UniProtKB:Q53HL2] xref: UniProtKB:Q53HL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001839 ! BOREA_HUMAN [Term] id: CCO:B0063952 name: BORG2_HUMAN-Phosphoserine89 def: "Protein BORG2_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q9UKI2] xref: UniProtKB:Q9UKI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001650 ! cytoskeletal regulatory protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059193 ! BORG2_HUMAN [Term] id: CCO:B0063953 name: BORG2_HUMAN-Phosphoserine91 def: "Protein BORG2_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q9UKI2] comment: By similarity xref: UniProtKB:Q9UKI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059193 ! BORG2_HUMAN [Term] id: CCO:B0063954 name: BORG2_HUMAN-Phosphoserine100 def: "Protein BORG2_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q9UKI2] xref: UniProtKB:Q9UKI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059193 ! BORG2_HUMAN [Term] id: CCO:B0063955 name: BORG4_HUMAN-Phosphoserine64 def: "Protein BORG4_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q9H3Q1] xref: UniProtKB:Q9H3Q1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058708 ! BORG4_HUMAN [Term] id: CCO:B0063956 name: BORG4_HUMAN-Phosphoserine138 def: "Protein BORG4_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q9H3Q1] xref: UniProtKB:Q9H3Q1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003532 ! GTP-Rho binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058708 ! BORG4_HUMAN [Term] id: CCO:B0063957 name: BORG4_HUMAN-Phosphoserine142 def: "Protein BORG4_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q9H3Q1] xref: UniProtKB:Q9H3Q1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058708 ! BORG4_HUMAN [Term] id: CCO:B0063958 name: BORG4_HUMAN-Phosphoserine174 def: "Protein BORG4_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:Q9H3Q1] xref: UniProtKB:Q9H3Q1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058708 ! BORG4_HUMAN [Term] id: CCO:B0063959 name: BORG4_HUMAN-Phosphoserine292 def: "Protein BORG4_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q9H3Q1] xref: UniProtKB:Q9H3Q1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058708 ! BORG4_HUMAN [Term] id: CCO:B0063960 name: BORG4_HUMAN-Phosphoserine295 def: "Protein BORG4_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q9H3Q1] xref: UniProtKB:Q9H3Q1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058708 ! BORG4_HUMAN [Term] id: CCO:B0063961 name: BORG5_HUMAN-Phosphoserine101 def: "Protein BORG5_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063962 name: BORG5_HUMAN-Phosphoserine106 def: "Protein BORG5_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063963 name: BORG5_HUMAN-Phosphoserine113 def: "Protein BORG5_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063964 name: BORG5_HUMAN-Phosphoserine121 def: "Protein BORG5_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063965 name: BORG5_HUMAN-Phosphoserine190 def: "Protein BORG5_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063966 name: BORG5_HUMAN-Phosphoserine192 def: "Protein BORG5_HUMAN with the residue 192 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063967 name: BORG5_HUMAN-Phosphoserine195 def: "Protein BORG5_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063968 name: BORG5_HUMAN-Phosphoserine350 def: "Protein BORG5_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063969 name: BORG5_HUMAN-Phosphoserine353 def: "Protein BORG5_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q00587] xref: UniProtKB:Q00587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:B0063970 name: BPTF_HUMAN-Phosphoserine216 def: "Protein BPTF_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063971 name: BPTF_HUMAN-Phosphoserine572 def: "Protein BPTF_HUMAN with the residue 572 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063972 name: BPTF_HUMAN-Phosphoserine763 def: "Protein BPTF_HUMAN with the residue 763 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063973 name: BPTF_HUMAN-Phosphoserine817 def: "Protein BPTF_HUMAN with the residue 817 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063974 name: BPTF_HUMAN-Phosphotyrosine839 def: "Protein BPTF_HUMAN with the residue 839 substituted with Phosphotyrosine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063975 name: BPTF_HUMAN-Phosphothreonine1064 def: "Protein BPTF_HUMAN with the residue 1064 substituted with Phosphothreonine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063976 name: BPTF_HUMAN-Phosphoserine1300 def: "Protein BPTF_HUMAN with the residue 1300 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063977 name: BPTF_HUMAN-Phosphoserine1827 def: "Protein BPTF_HUMAN with the residue 1827 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063978 name: BPTF_HUMAN-Phosphoserine1833 def: "Protein BPTF_HUMAN with the residue 1833 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063979 name: BPTF_HUMAN-Phosphoserine2098 def: "Protein BPTF_HUMAN with the residue 2098 substituted with Phosphoserine" [UniProtKB:Q12830] xref: UniProtKB:Q12830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055846 ! BPTF_HUMAN [Term] id: CCO:B0063980 name: BRAF1_HUMAN-N-acetylalanine2 def: "Protein BRAF1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P15056] xref: UniProtKB:P15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:B0063981 name: BRAP_HUMAN-Phosphoserine52 def: "Protein BRAP_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q7Z569] xref: UniProtKB:Q7Z569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:B0063982 name: BRCA1_HUMAN-Phosphoserine395 def: "Protein BRCA1_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0063983 name: BRCA1_HUMAN-Phosphoserine398 def: "Protein BRCA1_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0063984 name: BRCA1_HUMAN-Phosphoserine403 def: "Protein BRCA1_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0063985 name: BRCA1_HUMAN-Phosphoserine753 def: "Protein BRCA1_HUMAN with the residue 753 substituted with Phosphoserine" [UniProtKB:P38398] xref: UniProtKB:P38398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:B0063986 name: BRD8_HUMAN-Phosphoserine637 def: "Protein BRD8_HUMAN with the residue 637 substituted with Phosphoserine" [UniProtKB:Q9H0E9] xref: UniProtKB:Q9H0E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001239 ! thyroid hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058651 ! BRD8_HUMAN [Term] id: CCO:B0063987 name: BRD8_HUMAN-Phosphoserine641 def: "Protein BRD8_HUMAN with the residue 641 substituted with Phosphoserine" [UniProtKB:Q9H0E9] xref: UniProtKB:Q9H0E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058651 ! BRD8_HUMAN [Term] id: CCO:B0063988 name: BRD8_HUMAN-Phosphothreonine1151 def: "Protein BRD8_HUMAN with the residue 1151 substituted with Phosphothreonine" [UniProtKB:Q9H0E9] xref: UniProtKB:Q9H0E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058651 ! BRD8_HUMAN [Term] id: CCO:B0063989 name: BRD8_HUMAN-Phosphoserine1152 def: "Protein BRD8_HUMAN with the residue 1152 substituted with Phosphoserine" [UniProtKB:Q9H0E9] xref: UniProtKB:Q9H0E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058651 ! BRD8_HUMAN [Term] id: CCO:B0063990 name: BRPF1_HUMAN-Phosphoserine120 def: "Protein BRPF1_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P55201] xref: UniProtKB:P55201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038294 ! BRPF1_HUMAN [Term] id: CCO:B0063991 name: BRPF1_HUMAN-Phosphoserine1187 def: "Protein BRPF1_HUMAN with the residue 1187 substituted with Phosphoserine" [UniProtKB:P55201] xref: UniProtKB:P55201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038294 ! BRPF1_HUMAN [Term] id: CCO:B0063992 name: BRWD1_HUMAN-Phosphoserine696 def: "Protein BRWD1_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0063993 name: BRWD1_HUMAN-Phosphoserine701 def: "Protein BRWD1_HUMAN with the residue 701 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0063994 name: BRWD1_HUMAN-Phosphothreonine1275 def: "Protein BRWD1_HUMAN with the residue 1275 substituted with Phosphothreonine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0063995 name: BRWD1_HUMAN-Phosphoserine1289 def: "Protein BRWD1_HUMAN with the residue 1289 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0063996 name: BRWD1_HUMAN-Phosphoserine1605 def: "Protein BRWD1_HUMAN with the residue 1605 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0063997 name: BRWD1_HUMAN-Phosphoserine1607 def: "Protein BRWD1_HUMAN with the residue 1607 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0063998 name: BRWD1_HUMAN-Phosphoserine1786 def: "Protein BRWD1_HUMAN with the residue 1786 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0063999 name: BRWD1_HUMAN-Phosphoserine1788 def: "Protein BRWD1_HUMAN with the residue 1788 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064000 name: BRWD1_HUMAN-Phosphoserine1793 def: "Protein BRWD1_HUMAN with the residue 1793 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064001 name: BRWD1_HUMAN-Phosphoserine1904 def: "Protein BRWD1_HUMAN with the residue 1904 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064002 name: BRWD1_HUMAN-Phosphoserine1905 def: "Protein BRWD1_HUMAN with the residue 1905 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064003 name: BRWD1_HUMAN-Phosphoserine1907 def: "Protein BRWD1_HUMAN with the residue 1907 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064004 name: BRWD1_HUMAN-Phosphoserine1910 def: "Protein BRWD1_HUMAN with the residue 1910 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064005 name: BRWD1_HUMAN-Phosphoserine2018 def: "Protein BRWD1_HUMAN with the residue 2018 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064006 name: BRWD1_HUMAN-Phosphoserine2020 def: "Protein BRWD1_HUMAN with the residue 2020 substituted with Phosphoserine" [UniProtKB:Q9NSI6] xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064007 name: BRWD1_HUMAN-Phosphoserine2052 def: "Protein BRWD1_HUMAN with the residue 2052 substituted with Phosphoserine" [UniProtKB:Q9NSI6] comment: By similarity xref: UniProtKB:Q9NSI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058920 ! BRWD1_HUMAN [Term] id: CCO:B0064008 name: BT3L3_HUMAN-Phosphoserine77 def: "Protein BT3L3_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q13892] xref: UniProtKB:Q13892 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0032323 ! BT3L3_HUMAN [Term] id: CCO:B0064009 name: BTAF1_HUMAN-Phosphotyrosine1359 def: "Protein BTAF1_HUMAN with the residue 1359 substituted with Phosphotyrosine" [UniProtKB:O14981] xref: UniProtKB:O14981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016937 ! BTAF1_HUMAN [Term] id: CCO:B0064010 name: BTB14_HUMAN-Phosphoserine259 def: "Protein BTB14_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:Q96RE7] comment: by PKC; By similarity xref: UniProtKB:Q96RE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058374 ! BTB14_HUMAN [Term] id: CCO:B0064011 name: BTF3_HUMAN-Phosphoserine30 def: "Protein BTF3_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:P20290] xref: UniProtKB:P20290 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032333 ! BTF3_HUMAN [Term] id: CCO:B0064012 name: BTK_HUMAN-N-acetylalanine2 def: "Protein BTK_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q06187] xref: UniProtKB:Q06187 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:B0064013 name: BTK_HUMAN-Phosphotyrosine40 def: "Protein BTK_HUMAN with the residue 40 substituted with Phosphotyrosine" [UniProtKB:Q06187] comment: By similarity xref: UniProtKB:Q06187 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:B0064014 name: BTK_HUMAN-Phosphotyrosine223 def: "Protein BTK_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:Q06187] comment: by autocatalysis; xref: UniProtKB:Q06187 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:B0064015 name: BTK_HUMAN-Phosphotyrosine344 def: "Protein BTK_HUMAN with the residue 344 substituted with Phosphotyrosine" [UniProtKB:Q06187] comment: By similarity xref: UniProtKB:Q06187 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:B0064016 name: BTK_HUMAN-Phosphotyrosine551 def: "Protein BTK_HUMAN with the residue 551 substituted with Phosphotyrosine" [UniProtKB:Q06187] comment: by autocatalysis; xref: UniProtKB:Q06187 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:B0064017 name: BZW1_HUMAN-Phosphoserine411 def: "Protein BZW1_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q7L1Q6] xref: UniProtKB:Q7L1Q6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057115 ! BZW1_HUMAN [Term] id: CCO:B0064018 name: BZW1_HUMAN-Phosphoserine413 def: "Protein BZW1_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q7L1Q6] xref: UniProtKB:Q7L1Q6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057115 ! BZW1_HUMAN [Term] id: CCO:B0064019 name: C2D1A_HUMAN-Phosphotyrosine207 def: "Protein C2D1A_HUMAN with the residue 207 substituted with Phosphotyrosine" [UniProtKB:Q6P1N0] xref: UniProtKB:Q6P1N0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056880 ! C2D1A_HUMAN [Term] id: CCO:B0064020 name: C2D1A_HUMAN-Phosphoserine208 def: "Protein C2D1A_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q6P1N0] xref: UniProtKB:Q6P1N0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056880 ! C2D1A_HUMAN [Term] id: CCO:B0064021 name: C2D1A_HUMAN-Phosphoserine455 def: "Protein C2D1A_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q6P1N0] xref: UniProtKB:Q6P1N0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056880 ! C2D1A_HUMAN [Term] id: CCO:B0064022 name: C3AR_HUMAN-Sulfotyrosine174 def: "Protein C3AR_HUMAN with the residue 174 substituted with Sulfotyrosine" [UniProtKB:Q16581] xref: UniProtKB:Q16581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001230 ! complement component C3a receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001284 ! anaphylatoxin receptor activity relationship: has_function CCO:F0001285 ! C3a anaphylatoxin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056154 ! C3AR_HUMAN [Term] id: CCO:B0064023 name: C3AR_HUMAN-Sulfotyrosine184 def: "Protein C3AR_HUMAN with the residue 184 substituted with Sulfotyrosine" [UniProtKB:Q16581] xref: UniProtKB:Q16581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056154 ! C3AR_HUMAN [Term] id: CCO:B0064024 name: C3AR_HUMAN-Sulfotyrosine318 def: "Protein C3AR_HUMAN with the residue 318 substituted with Sulfotyrosine" [UniProtKB:Q16581] xref: UniProtKB:Q16581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056154 ! C3AR_HUMAN [Term] id: CCO:B0064025 name: C5ARL_HUMAN-Phosphoserine326 def: "Protein C5ARL_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:Q9P296] comment: By similarity xref: UniProtKB:Q9P296 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001286 ! C5a anaphylatoxin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059055 ! C5ARL_HUMAN [Term] id: CCO:B0064026 name: C5AR_HUMAN-Sulfotyrosine11 def: "Protein C5AR_HUMAN with the residue 11 substituted with Sulfotyrosine" [UniProtKB:P21730] xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064027 name: C5AR_HUMAN-Sulfotyrosine14 def: "Protein C5AR_HUMAN with the residue 14 substituted with Sulfotyrosine" [UniProtKB:P21730] xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064028 name: C5AR_HUMAN-Phosphoserine314 def: "Protein C5AR_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:P21730] comment: Probable xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064029 name: C5AR_HUMAN-Phosphoserine317 def: "Protein C5AR_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:P21730] comment: Probable xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064030 name: C5AR_HUMAN-Phosphoserine327 def: "Protein C5AR_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:P21730] comment: Probable xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001284 ! anaphylatoxin receptor activity relationship: has_function CCO:F0001286 ! C5a anaphylatoxin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064031 name: C5AR_HUMAN-Phosphoserine332 def: "Protein C5AR_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:P21730] comment: Probable xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064032 name: C5AR_HUMAN-Phosphoserine334 def: "Protein C5AR_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:P21730] comment: Probable xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064033 name: C5AR_HUMAN-Phosphoserine338 def: "Protein C5AR_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:P21730] comment: Probable xref: UniProtKB:P21730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055137 ! C5AR_HUMAN [Term] id: CCO:B0064034 name: CABIN_HUMAN-Phosphothreonine2089 def: "Protein CABIN_HUMAN with the residue 2089 substituted with Phosphothreonine" [UniProtKB:Q9Y6J0] xref: UniProtKB:Q9Y6J0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059407 ! CABIN_HUMAN [Term] id: CCO:B0064035 name: CABYR_HUMAN-Phosphothreonine151 def: "Protein CABYR_HUMAN with the residue 151 substituted with Phosphothreonine" [UniProtKB:O75952] comment: Probable xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064036 name: CABYR_HUMAN-Phosphoserine155 def: "Protein CABYR_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:O75952] comment: Probable xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064037 name: CABYR_HUMAN-Phosphoserine240 def: "Protein CABYR_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:O75952] xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064038 name: CABYR_HUMAN-Phosphoserine359 def: "Protein CABYR_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:O75952] xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064039 name: CABYR_HUMAN-Phosphoserine362 def: "Protein CABYR_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:O75952] xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0002007 ! cAMP-dependent protein kinase regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064040 name: CABYR_HUMAN-Phosphoserine413 def: "Protein CABYR_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:O75952] xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064041 name: CABYR_HUMAN-Phosphoserine461 def: "Protein CABYR_HUMAN with the residue 461 substituted with Phosphoserine" [UniProtKB:O75952] xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064042 name: CABYR_HUMAN-Phosphoserine469 def: "Protein CABYR_HUMAN with the residue 469 substituted with Phosphoserine" [UniProtKB:O75952] xref: UniProtKB:O75952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054680 ! CABYR_HUMAN [Term] id: CCO:B0064043 name: CAC1D_HUMAN-Phosphoserine1475 def: "Protein CAC1D_HUMAN with the residue 1475 substituted with Phosphoserine" [UniProtKB:Q01668] comment: by PKA; Potential xref: UniProtKB:Q01668 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001513 ! voltage-gated calcium channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001840 ! high voltage-gated calcium channel activity relationship: has_function CCO:F0002727 ! dihydropyridine-sensitive calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000448 ! voltage-gated calcium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055694 ! CAC1D_HUMAN [Term] id: CCO:B0064044 name: CAC1D_HUMAN-Phosphoserine1905 def: "Protein CAC1D_HUMAN with the residue 1905 substituted with Phosphoserine" [UniProtKB:Q01668] xref: UniProtKB:Q01668 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055694 ! CAC1D_HUMAN [Term] id: CCO:B0064045 name: CACB3_HUMAN-Phosphotyrosine171 def: "Protein CACB3_HUMAN with the residue 171 substituted with Phosphotyrosine" [UniProtKB:P54284] xref: UniProtKB:P54284 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001513 ! voltage-gated calcium channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002727 ! dihydropyridine-sensitive calcium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000448 ! voltage-gated calcium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055513 ! CACB3_HUMAN [Term] id: CCO:B0064046 name: CACO1_HUMAN-Phosphoserine563 def: "Protein CACO1_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:Q9P1Z2] comment: By similarity xref: UniProtKB:Q9P1Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059047 ! CACO1_HUMAN [Term] id: CCO:B0064047 name: CAF1A_HUMAN-Phosphoserine206 def: "Protein CAF1A_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0064048 name: CAF1A_HUMAN-Phosphothreonine704 def: "Protein CAF1A_HUMAN with the residue 704 substituted with Phosphothreonine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0064049 name: CAF1A_HUMAN-Phosphoserine855 def: "Protein CAF1A_HUMAN with the residue 855 substituted with Phosphoserine" [UniProtKB:Q13111] xref: UniProtKB:Q13111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:B0064050 name: CAF1B_HUMAN-Phosphoserine409 def: "Protein CAF1B_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0064051 name: CAF1B_HUMAN-Phosphothreonine419 def: "Protein CAF1B_HUMAN with the residue 419 substituted with Phosphothreonine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0064052 name: CAF1B_HUMAN-Phosphothreonine433 def: "Protein CAF1B_HUMAN with the residue 433 substituted with Phosphothreonine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0064053 name: CAF1B_HUMAN-Phosphothreonine524 def: "Protein CAF1B_HUMAN with the residue 524 substituted with Phosphothreonine" [UniProtKB:Q13112] xref: UniProtKB:Q13112 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001743 ! CAF1B_HUMAN [Term] id: CCO:B0064054 name: CALCA_HUMAN-Phenylalanine amide119 def: "Protein CALCA_HUMAN with the residue 119 substituted with Phenylalanine amide" [UniProtKB:P06881] xref: UniProtKB:P06881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054907 ! CALCA_HUMAN [Term] id: CCO:B0064055 name: CALCB_HUMAN-Phenylalanine amide118 def: "Protein CALCB_HUMAN with the residue 118 substituted with Phenylalanine amide" [UniProtKB:P10092] xref: UniProtKB:P10092 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054970 ! CALCB_HUMAN [Term] id: CCO:B0064056 name: CALC_HUMAN-Proline amide116 def: "Protein CALC_HUMAN with the residue 116 substituted with Proline amide" [UniProtKB:P01258] xref: UniProtKB:P01258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054845 ! CALC_HUMAN [Term] id: CCO:B0064057 name: CALL5_HUMAN-N-acetylalanine2 def: "Protein CALL5_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9NZT1] xref: UniProtKB:Q9NZT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059016 ! CALL5_HUMAN [Term] id: CCO:B0064058 name: CANB1_HUMAN-Phosphotyrosine106 def: "Protein CANB1_HUMAN with the residue 106 substituted with Phosphotyrosine" [UniProtKB:P63098] comment: By similarity xref: UniProtKB:P63098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001088 ! calcium-dependent protein serine/threonine phosphatase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001648 ! calmodulin inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000504 ! calcineurin complex relationship: transformation_of CCO:B0055624 ! CANB1_HUMAN [Term] id: CCO:B0064059 name: CAP1_HUMAN-Phosphoserine290 def: "Protein CAP1_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0064060 name: CAP1_HUMAN-Phosphoserine295 def: "Protein CAP1_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0064061 name: CAP1_HUMAN-Phosphoserine301 def: "Protein CAP1_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0064062 name: CAP1_HUMAN-Phosphoserine308 def: "Protein CAP1_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:Q01518] xref: UniProtKB:Q01518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023915 ! CAP1_HUMAN [Term] id: CCO:B0064063 name: CAPR2_HUMAN-Phosphoserine547 def: "Protein CAPR2_HUMAN with the residue 547 substituted with Phosphoserine" [UniProtKB:Q6IMN6] xref: UniProtKB:Q6IMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056819 ! CAPR2_HUMAN [Term] id: CCO:B0064064 name: CAPR2_HUMAN-Phosphoserine554 def: "Protein CAPR2_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:Q6IMN6] xref: UniProtKB:Q6IMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056819 ! CAPR2_HUMAN [Term] id: CCO:B0064065 name: CAPR2_HUMAN-Phosphothreonine560 def: "Protein CAPR2_HUMAN with the residue 560 substituted with Phosphothreonine" [UniProtKB:Q6IMN6] xref: UniProtKB:Q6IMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056819 ! CAPR2_HUMAN [Term] id: CCO:B0064066 name: CAPR2_HUMAN-Phosphotyrosine924 def: "Protein CAPR2_HUMAN with the residue 924 substituted with Phosphotyrosine" [UniProtKB:Q6IMN6] xref: UniProtKB:Q6IMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0056819 ! CAPR2_HUMAN [Term] id: CCO:B0064067 name: CAR14_HUMAN-Phosphoserine544 def: "Protein CAR14_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:Q9BXL6] xref: UniProtKB:Q9BXL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008000 ! CARD domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0058558 ! CAR14_HUMAN [Term] id: CCO:B0064068 name: CARD6_HUMAN-Phosphoserine468 def: "Protein CARD6_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:Q9BX69] xref: UniProtKB:Q9BX69 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058544 ! CARD6_HUMAN [Term] id: CCO:B0064069 name: CARD9_HUMAN-Phosphoserine460 def: "Protein CARD9_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q9H257] xref: UniProtKB:Q9H257 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058679 ! CARD9_HUMAN [Term] id: CCO:B0064070 name: CASC5_HUMAN-Phosphoserine1845 def: "Protein CASC5_HUMAN with the residue 1845 substituted with Phosphoserine" [UniProtKB:Q8NG31] xref: UniProtKB:Q8NG31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:B0064071 name: CASL_HUMAN-Phosphotyrosine317 def: "Protein CASL_HUMAN with the residue 317 substituted with Phosphotyrosine" [UniProtKB:Q14511] xref: UniProtKB:Q14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001782 ! CASL_HUMAN [Term] id: CCO:B0064072 name: CASL_HUMAN-Phosphotyrosine345 def: "Protein CASL_HUMAN with the residue 345 substituted with Phosphotyrosine" [UniProtKB:Q14511] xref: UniProtKB:Q14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001782 ! CASL_HUMAN [Term] id: CCO:B0064073 name: CASP3_HUMAN-Phosphoserine26 def: "Protein CASP3_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:P42574] comment: By similarity xref: UniProtKB:P42574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055351 ! CASP3_HUMAN [Term] id: CCO:B0064074 name: CASP3_HUMAN-S-nitrosocysteine163 def: "Protein CASP3_HUMAN with the residue 163 substituted with S-nitrosocysteine" [UniProtKB:P42574] comment: in inhibited form; xref: UniProtKB:P42574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055351 ! CASP3_HUMAN [Term] id: CCO:B0064075 name: CASP4_HUMAN-Phosphoserine83 def: "Protein CASP4_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P49662] xref: UniProtKB:P49662 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040471 ! CASP4_HUMAN [Term] id: CCO:B0064076 name: CASP6_HUMAN-Phosphoserine257 def: "Protein CASP6_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:P55212] xref: UniProtKB:P55212 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055531 ! CASP6_HUMAN [Term] id: CCO:B0064077 name: CASP8_HUMAN-Phosphoserine188 def: "Protein CASP8_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:Q14790] comment: By similarity xref: UniProtKB:Q14790 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:B0064078 name: CASP8_HUMAN-Phosphoserine219 def: "Protein CASP8_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q14790] xref: UniProtKB:Q14790 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:B0064079 name: CASP8_HUMAN-Phosphotyrosine334 def: "Protein CASP8_HUMAN with the residue 334 substituted with Phosphotyrosine" [UniProtKB:Q14790] xref: UniProtKB:Q14790 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:B0064080 name: CASP9_HUMAN-Phosphothreonine125 def: "Protein CASP9_HUMAN with the residue 125 substituted with Phosphothreonine" [UniProtKB:P55211] xref: UniProtKB:P55211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005903 ! CASP9_HUMAN [Term] id: CCO:B0064081 name: CASP9_HUMAN-Phosphoserine302 def: "Protein CASP9_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:P55211] xref: UniProtKB:P55211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005903 ! CASP9_HUMAN [Term] id: CCO:B0064082 name: CASP9_HUMAN-Phosphoserine307 def: "Protein CASP9_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:P55211] xref: UniProtKB:P55211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004519 ! caspase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005903 ! CASP9_HUMAN [Term] id: CCO:B0064083 name: CASP9_HUMAN-Phosphoserine310 def: "Protein CASP9_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:P55211] xref: UniProtKB:P55211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005903 ! CASP9_HUMAN [Term] id: CCO:B0064084 name: CASPA_HUMAN-Phosphoserine216 def: "Protein CASPA_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q92851] xref: UniProtKB:Q92851 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058106 ! CASPA_HUMAN [Term] id: CCO:B0064085 name: CATA_HUMAN-Phosphotyrosine231 def: "Protein CATA_HUMAN with the residue 231 substituted with Phosphotyrosine" [UniProtKB:P04040] xref: UniProtKB:P04040 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019335 ! CATA_HUMAN [Term] id: CCO:B0064086 name: CATA_HUMAN-Phosphotyrosine308 def: "Protein CATA_HUMAN with the residue 308 substituted with Phosphotyrosine" [UniProtKB:P04040] xref: UniProtKB:P04040 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019335 ! CATA_HUMAN [Term] id: CCO:B0064087 name: CATA_HUMAN-Phosphoserine422 def: "Protein CATA_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:P04040] comment: By similarity xref: UniProtKB:P04040 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019335 ! CATA_HUMAN [Term] id: CCO:B0064088 name: CATA_HUMAN-Phosphoserine517 def: "Protein CATA_HUMAN with the residue 517 substituted with Phosphoserine" [UniProtKB:P04040] comment: By similarity xref: UniProtKB:P04040 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019335 ! CATA_HUMAN [Term] id: CCO:B0064089 name: CAYP1_HUMAN-Phosphoserine40 def: "Protein CAYP1_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q13938] comment: by PKA; Potential xref: UniProtKB:Q13938 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055953 ! CAYP1_HUMAN [Term] id: CCO:B0064090 name: CBLB_HUMAN-Phosphoserine521 def: "Protein CBLB_HUMAN with the residue 521 substituted with Phosphoserine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0064091 name: CBLB_HUMAN-Phosphoserine525 def: "Protein CBLB_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0064092 name: CBLB_HUMAN-Phosphoserine529 def: "Protein CBLB_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:Q13191] xref: UniProtKB:Q13191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005819 ! CBLB_HUMAN [Term] id: CCO:B0064093 name: CBLC_HUMAN-Phosphoserine40 def: "Protein CBLC_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q9ULV8] xref: UniProtKB:Q9ULV8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059234 ! CBLC_HUMAN [Term] id: CCO:B0064094 name: CBP_HUMAN-Phosphoserine121 def: "Protein CBP_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008146 ! MyoD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000011 ! histone acetyltransferase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0064095 name: CBP_HUMAN-Phosphoserine2063 def: "Protein CBP_HUMAN with the residue 2063 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0064096 name: CBP_HUMAN-Phosphoserine2076 def: "Protein CBP_HUMAN with the residue 2076 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0064097 name: CBP_HUMAN-Phosphoserine2079 def: "Protein CBP_HUMAN with the residue 2079 substituted with Phosphoserine" [UniProtKB:Q92793] xref: UniProtKB:Q92793 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:B0064098 name: CBX3_HUMAN-Phosphoserine93 def: "Protein CBX3_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q13185] xref: UniProtKB:Q13185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055884 ! CBX3_HUMAN [Term] id: CCO:B0064099 name: CBX3_HUMAN-Phosphoserine95 def: "Protein CBX3_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q13185] xref: UniProtKB:Q13185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055884 ! CBX3_HUMAN [Term] id: CCO:B0064100 name: CBX3_HUMAN-Phosphoserine176 def: "Protein CBX3_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q13185] xref: UniProtKB:Q13185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000254 ! nuclear inner membrane relationship: located_in CCO:C0000299 ! polytene chromosome chromocenter relationship: located_in CCO:C0000309 ! nuclear euchromatin relationship: located_in CCO:C0000310 ! nuclear heterochromatin relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0002169 ! condensed chromosome, centromeric region relationship: located_in CCO:C0002174 ! nuclear centromeric heterochromatin relationship: transformation_of CCO:B0055884 ! CBX3_HUMAN [Term] id: CCO:B0064101 name: CBX4_HUMAN-Phosphoserine413 def: "Protein CBX4_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:O00257] xref: UniProtKB:O00257 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054304 ! CBX4_HUMAN [Term] id: CCO:B0064102 name: CBX4_HUMAN-Phosphothreonine495 def: "Protein CBX4_HUMAN with the residue 495 substituted with Phosphothreonine" [UniProtKB:O00257] xref: UniProtKB:O00257 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054304 ! CBX4_HUMAN [Term] id: CCO:B0064103 name: CBX6_HUMAN-Phosphoserine301 def: "Protein CBX6_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:O95503] xref: UniProtKB:O95503 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054770 ! CBX6_HUMAN [Term] id: CCO:B0064104 name: CBX6_HUMAN-Phosphoserine303 def: "Protein CBX6_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:O95503] xref: UniProtKB:O95503 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054770 ! CBX6_HUMAN [Term] id: CCO:B0064105 name: CBX8_HUMAN-Phosphoserine110 def: "Protein CBX8_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:Q9HC52] xref: UniProtKB:Q9HC52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:B0064106 name: CBX8_HUMAN-Phosphoserine130 def: "Protein CBX8_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q9HC52] xref: UniProtKB:Q9HC52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:B0064107 name: CBX8_HUMAN-Phosphoserine256 def: "Protein CBX8_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q9HC52] xref: UniProtKB:Q9HC52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:B0064108 name: CBX8_HUMAN-Phosphoserine265 def: "Protein CBX8_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q9HC52] xref: UniProtKB:Q9HC52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:B0064109 name: CBX8_HUMAN-Phosphoserine332 def: "Protein CBX8_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:Q9HC52] xref: UniProtKB:Q9HC52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001285 ! PcG protein complex relationship: transformation_of CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:B0064110 name: CBX8_HUMAN-Phosphoserine352 def: "Protein CBX8_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q9HC52] xref: UniProtKB:Q9HC52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:B0064111 name: CCKN_HUMAN-Sulfotyrosine97 def: "Protein CCKN_HUMAN with the residue 97 substituted with Sulfotyrosine" [UniProtKB:P06307] xref: UniProtKB:P06307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001004 ! axon relationship: transformation_of CCO:B0054903 ! CCKN_HUMAN [Term] id: CCO:B0064112 name: CCKN_HUMAN-Phenylalanine amide103 def: "Protein CCKN_HUMAN with the residue 103 substituted with Phenylalanine amide" [UniProtKB:P06307] xref: UniProtKB:P06307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054903 ! CCKN_HUMAN [Term] id: CCO:B0064113 name: CCKN_HUMAN-Sulfotyrosine111 def: "Protein CCKN_HUMAN with the residue 111 substituted with Sulfotyrosine" [UniProtKB:P06307] comment: By similarity xref: UniProtKB:P06307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054903 ! CCKN_HUMAN [Term] id: CCO:B0064114 name: CCKN_HUMAN-Sulfotyrosine113 def: "Protein CCKN_HUMAN with the residue 113 substituted with Sulfotyrosine" [UniProtKB:P06307] comment: By similarity xref: UniProtKB:P06307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054903 ! CCKN_HUMAN [Term] id: CCO:B0064115 name: CCM2_HUMAN-Phosphoserine384 def: "Protein CCM2_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q9BSQ5] xref: UniProtKB:Q9BSQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058509 ! CCM2_HUMAN [Term] id: CCO:B0064116 name: CCNH_HUMAN-Phosphoserine322 def: "Protein CCNH_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:P51946] xref: UniProtKB:P51946 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001652 ! CCNH_HUMAN [Term] id: CCO:B0064117 name: CCNL1_HUMAN-Phosphothreonine325 def: "Protein CCNL1_HUMAN with the residue 325 substituted with Phosphothreonine" [UniProtKB:Q9UK58] xref: UniProtKB:Q9UK58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002218 ! CCNL1_HUMAN [Term] id: CCO:B0064118 name: CCNL1_HUMAN-Phosphoserine335 def: "Protein CCNL1_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q9UK58] xref: UniProtKB:Q9UK58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002218 ! CCNL1_HUMAN [Term] id: CCO:B0064119 name: CCNL1_HUMAN-Phosphoserine338 def: "Protein CCNL1_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:Q9UK58] xref: UniProtKB:Q9UK58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002218 ! CCNL1_HUMAN [Term] id: CCO:B0064120 name: CCNL1_HUMAN-Phosphoserine342 def: "Protein CCNL1_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:Q9UK58] xref: UniProtKB:Q9UK58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002218 ! CCNL1_HUMAN [Term] id: CCO:B0064121 name: CCR10_HUMAN-Phosphothreonine295 def: "Protein CCR10_HUMAN with the residue 295 substituted with Phosphothreonine" [UniProtKB:P46092] xref: UniProtKB:P46092 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0018440 ! CCR10_HUMAN [Term] id: CCO:B0064122 name: CCR10_HUMAN-Phosphoserine296 def: "Protein CCR10_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:P46092] xref: UniProtKB:P46092 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018440 ! CCR10_HUMAN [Term] id: CCO:B0064123 name: CCR2_HUMAN-Sulfotyrosine26 def: "Protein CCR2_HUMAN with the residue 26 substituted with Sulfotyrosine" [UniProtKB:P41597] xref: UniProtKB:P41597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_function CCO:F0004740 ! CCR2 chemokine receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055344 ! CCR2_HUMAN [Term] id: CCO:B0064124 name: CCR5_HUMAN-Sulfotyrosine3 def: "Protein CCR5_HUMAN with the residue 3 substituted with Sulfotyrosine" [UniProtKB:P51681] xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064125 name: CCR5_HUMAN-Sulfotyrosine10 def: "Protein CCR5_HUMAN with the residue 10 substituted with Sulfotyrosine" [UniProtKB:P51681] comment: Potential xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064126 name: CCR5_HUMAN-Sulfotyrosine14 def: "Protein CCR5_HUMAN with the residue 14 substituted with Sulfotyrosine" [UniProtKB:P51681] comment: Potential xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064127 name: CCR5_HUMAN-Sulfotyrosine15 def: "Protein CCR5_HUMAN with the residue 15 substituted with Sulfotyrosine" [UniProtKB:P51681] comment: Potential xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064128 name: CCR5_HUMAN-Phosphoserine336 def: "Protein CCR5_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:P51681] comment: by BARK1; xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064129 name: CCR5_HUMAN-Phosphoserine337 def: "Protein CCR5_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:P51681] comment: by BARK1; xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064130 name: CCR5_HUMAN-Phosphoserine342 def: "Protein CCR5_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:P51681] comment: by BARK1; xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064131 name: CCR5_HUMAN-Phosphoserine349 def: "Protein CCR5_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:P51681] comment: by BARK1; xref: UniProtKB:P51681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:B0064132 name: CCR7_HUMAN-Phosphoserine151 def: "Protein CCR7_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:P32248] xref: UniProtKB:P32248 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055258 ! CCR7_HUMAN [Term] id: CCO:B0064133 name: CD19_HUMAN-Phosphoserine227 def: "Protein CD19_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P15391] comment: By similarity xref: UniProtKB:P15391 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055035 ! CD19_HUMAN [Term] id: CCO:B0064134 name: CD19_HUMAN-Phosphotyrosine348 def: "Protein CD19_HUMAN with the residue 348 substituted with Phosphotyrosine" [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055035 ! CD19_HUMAN [Term] id: CCO:B0064135 name: CD19_HUMAN-Phosphotyrosine378 def: "Protein CD19_HUMAN with the residue 378 substituted with Phosphotyrosine" [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055035 ! CD19_HUMAN [Term] id: CCO:B0064136 name: CD19_HUMAN-Phosphotyrosine409 def: "Protein CD19_HUMAN with the residue 409 substituted with Phosphotyrosine" [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055035 ! CD19_HUMAN [Term] id: CCO:B0064137 name: CD19_HUMAN-Phosphotyrosine439 def: "Protein CD19_HUMAN with the residue 439 substituted with Phosphotyrosine" [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055035 ! CD19_HUMAN [Term] id: CCO:B0064138 name: CD19_HUMAN-Phosphoserine497 def: "Protein CD19_HUMAN with the residue 497 substituted with Phosphoserine" [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055035 ! CD19_HUMAN [Term] id: CCO:B0064139 name: CD226_HUMAN-Phosphoserine290 def: "Protein CD226_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:Q15762] xref: UniProtKB:Q15762 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056106 ! CD226_HUMAN [Term] id: CCO:B0064140 name: CD226_HUMAN-Phosphotyrosine322 def: "Protein CD226_HUMAN with the residue 322 substituted with Phosphotyrosine" [UniProtKB:Q15762] xref: UniProtKB:Q15762 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056106 ! CD226_HUMAN [Term] id: CCO:B0064141 name: CD244_HUMAN-Phosphotyrosine271 def: "Protein CD244_HUMAN with the residue 271 substituted with Phosphotyrosine" [UniProtKB:Q9BZW8] xref: UniProtKB:Q9BZW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058610 ! CD244_HUMAN [Term] id: CCO:B0064142 name: CD244_HUMAN-Phosphotyrosine369 def: "Protein CD244_HUMAN with the residue 369 substituted with Phosphotyrosine" [UniProtKB:Q9BZW8] comment: By similarity xref: UniProtKB:Q9BZW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058610 ! CD244_HUMAN [Term] id: CCO:B0064143 name: CD276_HUMAN-Phosphoserine525 def: "Protein CD276_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q5ZPR3] xref: UniProtKB:Q5ZPR3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056685 ! CD276_HUMAN [Term] id: CCO:B0064144 name: CD27_HUMAN-Phosphoserine219 def: "Protein CD27_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:P26842] comment: Potential xref: UniProtKB:P26842 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055193 ! CD27_HUMAN [Term] id: CCO:B0064145 name: CD2AP_HUMAN-Phosphoserine224 def: "Protein CD2AP_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:Q9Y5K6] xref: UniProtKB:Q9Y5K6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001678 ! beta-catenin binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: located_in CCO:C0001172 ! leading edge relationship: located_in CCO:C0001356 ! filamentous actin relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0002257 ! CD2AP_HUMAN [Term] id: CCO:B0064146 name: CD2L2_HUMAN-Phosphoserine47 def: "Protein CD2L2_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0064147 name: CD2L2_HUMAN-Phosphoserine574 def: "Protein CD2L2_HUMAN with the residue 574 substituted with Phosphoserine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0064148 name: CD2L2_HUMAN-Phosphothreonine758 def: "Protein CD2L2_HUMAN with the residue 758 substituted with Phosphothreonine" [UniProtKB:Q9UQ88] xref: UniProtKB:Q9UQ88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:B0064149 name: CD2L5_HUMAN-Phosphoserine349 def: "Protein CD2L5_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001060 ! cyclin-dependent protein kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0064150 name: CD2L5_HUMAN-Phosphothreonine871 def: "Protein CD2L5_HUMAN with the residue 871 substituted with Phosphothreonine" [UniProtKB:Q14004] xref: UniProtKB:Q14004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001771 ! CD2L5_HUMAN [Term] id: CCO:B0064151 name: CD33_HUMAN-Phosphotyrosine340 def: "Protein CD33_HUMAN with the residue 340 substituted with Phosphotyrosine" [UniProtKB:P20138] xref: UniProtKB:P20138 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055113 ! CD33_HUMAN [Term] id: CCO:B0064152 name: CD33_HUMAN-Phosphotyrosine358 def: "Protein CD33_HUMAN with the residue 358 substituted with Phosphotyrosine" [UniProtKB:P20138] xref: UniProtKB:P20138 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055113 ! CD33_HUMAN [Term] id: CCO:B0064153 name: CD3D_HUMAN-Phosphotyrosine149 def: "Protein CD3D_HUMAN with the residue 149 substituted with Phosphotyrosine" [UniProtKB:P04234] xref: UniProtKB:P04234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054890 ! CD3D_HUMAN [Term] id: CCO:B0064154 name: CD3D_HUMAN-Phosphotyrosine160 def: "Protein CD3D_HUMAN with the residue 160 substituted with Phosphotyrosine" [UniProtKB:P04234] xref: UniProtKB:P04234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: transformation_of CCO:B0054890 ! CD3D_HUMAN [Term] id: CCO:B0064155 name: CD3E_HUMAN-Phosphotyrosine188 def: "Protein CD3E_HUMAN with the residue 188 substituted with Phosphotyrosine" [UniProtKB:P07766] xref: UniProtKB:P07766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054916 ! CD3E_HUMAN [Term] id: CCO:B0064156 name: CD3E_HUMAN-Phosphotyrosine199 def: "Protein CD3E_HUMAN with the residue 199 substituted with Phosphotyrosine" [UniProtKB:P07766] xref: UniProtKB:P07766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054916 ! CD3E_HUMAN [Term] id: CCO:B0064157 name: CD3G_HUMAN-Phosphoserine145 def: "Protein CD3G_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:P09693] xref: UniProtKB:P09693 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054949 ! CD3G_HUMAN [Term] id: CCO:B0064158 name: CD3G_HUMAN-Phosphoserine148 def: "Protein CD3G_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:P09693] xref: UniProtKB:P09693 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054949 ! CD3G_HUMAN [Term] id: CCO:B0064159 name: CD3G_HUMAN-Phosphotyrosine160 def: "Protein CD3G_HUMAN with the residue 160 substituted with Phosphotyrosine" [UniProtKB:P09693] xref: UniProtKB:P09693 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054949 ! CD3G_HUMAN [Term] id: CCO:B0064160 name: CD3G_HUMAN-Phosphotyrosine171 def: "Protein CD3G_HUMAN with the residue 171 substituted with Phosphotyrosine" [UniProtKB:P09693] xref: UniProtKB:P09693 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_function CCO:F0005691 ! T cell receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: transformation_of CCO:B0054949 ! CD3G_HUMAN [Term] id: CCO:B0064161 name: CD3Z_HUMAN-Phosphoserine58 def: "Protein CD3Z_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064162 name: CD3Z_HUMAN-Phosphotyrosine64 def: "Protein CD3Z_HUMAN with the residue 64 substituted with Phosphotyrosine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064163 name: CD3Z_HUMAN-Phosphotyrosine72 def: "Protein CD3Z_HUMAN with the residue 72 substituted with Phosphotyrosine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064164 name: CD3Z_HUMAN-Phosphotyrosine83 def: "Protein CD3Z_HUMAN with the residue 83 substituted with Phosphotyrosine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064165 name: CD3Z_HUMAN-Phosphotyrosine111 def: "Protein CD3Z_HUMAN with the residue 111 substituted with Phosphotyrosine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064166 name: CD3Z_HUMAN-Phosphotyrosine123 def: "Protein CD3Z_HUMAN with the residue 123 substituted with Phosphotyrosine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064167 name: CD3Z_HUMAN-Phosphotyrosine142 def: "Protein CD3Z_HUMAN with the residue 142 substituted with Phosphotyrosine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064168 name: CD3Z_HUMAN-Phosphotyrosine153 def: "Protein CD3Z_HUMAN with the residue 153 substituted with Phosphotyrosine" [UniProtKB:P20963] xref: UniProtKB:P20963 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:B0064169 name: CD47_HUMAN-Pyrrolidone carboxylic acid19 def: "Protein CD47_HUMAN with the residue 19 substituted with Pyrrolidone carboxylic acid" [UniProtKB:Q08722] comment: Probable xref: UniProtKB:Q08722 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055793 ! CD47_HUMAN [Term] id: CCO:B0064170 name: CD5_HUMAN-Phosphoserine439 def: "Protein CD5_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:P06127] xref: UniProtKB:P06127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054901 ! CD5_HUMAN [Term] id: CCO:B0064171 name: CD5_HUMAN-Phosphotyrosine453 def: "Protein CD5_HUMAN with the residue 453 substituted with Phosphotyrosine" [UniProtKB:P06127] xref: UniProtKB:P06127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001365 ! scavenger receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054901 ! CD5_HUMAN [Term] id: CCO:B0064172 name: CD5_HUMAN-Phosphoserine460 def: "Protein CD5_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:P06127] xref: UniProtKB:P06127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054901 ! CD5_HUMAN [Term] id: CCO:B0064173 name: CD79A_HUMAN-Phosphotyrosine188 def: "Protein CD79A_HUMAN with the residue 188 substituted with Phosphotyrosine" [UniProtKB:P11912] comment: by SRC-type Tyr-kinases; By similarity xref: UniProtKB:P11912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054996 ! CD79A_HUMAN [Term] id: CCO:B0064174 name: CD79A_HUMAN-Phosphotyrosine210 def: "Protein CD79A_HUMAN with the residue 210 substituted with Phosphotyrosine" [UniProtKB:P11912] comment: by Tyr-kinases; By similarity xref: UniProtKB:P11912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000354 ! multivesicular body relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000889 ! B cell receptor complex relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0054996 ! CD79A_HUMAN [Term] id: CCO:B0064175 name: CD8B_HUMAN-Phosphotyrosine209 def: "Protein CD8B_HUMAN with the residue 209 substituted with Phosphotyrosine" [UniProtKB:P10966] comment: Potential xref: UniProtKB:P10966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054983 ! CD8B_HUMAN [Term] id: CCO:B0064176 name: CD97_HUMAN-Phosphoserine831 def: "Protein CD97_HUMAN with the residue 831 substituted with Phosphoserine" [UniProtKB:P48960] xref: UniProtKB:P48960 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055413 ! CD97_HUMAN [Term] id: CCO:B0064177 name: CD97_HUMAN-Phosphoserine833 def: "Protein CD97_HUMAN with the residue 833 substituted with Phosphoserine" [UniProtKB:P48960] xref: UniProtKB:P48960 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055413 ! CD97_HUMAN [Term] id: CCO:B0064178 name: CDA7L_HUMAN-Phosphoserine21 def: "Protein CDA7L_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064179 name: CDA7L_HUMAN-Phosphothreonine77 def: "Protein CDA7L_HUMAN with the residue 77 substituted with Phosphothreonine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064180 name: CDA7L_HUMAN-Phosphoserine79 def: "Protein CDA7L_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064181 name: CDA7L_HUMAN-Phosphoserine105 def: "Protein CDA7L_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064182 name: CDA7L_HUMAN-Phosphoserine108 def: "Protein CDA7L_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064183 name: CDA7L_HUMAN-Phosphoserine114 def: "Protein CDA7L_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064184 name: CDA7L_HUMAN-Phosphoserine117 def: "Protein CDA7L_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064185 name: CDA7L_HUMAN-Phosphoserine261 def: "Protein CDA7L_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:Q96GN5] xref: UniProtKB:Q96GN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058219 ! CDA7L_HUMAN [Term] id: CCO:B0064186 name: CDC20_HUMAN-Phosphoserine41 def: "Protein CDC20_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q12834] xref: UniProtKB:Q12834 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001733 ! CDC20_HUMAN [Term] id: CCO:B0064187 name: CDC23_HUMAN-Phosphothreonine578 def: "Protein CDC23_HUMAN with the residue 578 substituted with Phosphothreonine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0064188 name: CDC23_HUMAN-Phosphoserine587 def: "Protein CDC23_HUMAN with the residue 587 substituted with Phosphoserine" [UniProtKB:Q9UJX2] xref: UniProtKB:Q9UJX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002212 ! CDC23_HUMAN [Term] id: CCO:B0064189 name: CDC26_HUMAN-Phosphoserine42 def: "Protein CDC26_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q8NHZ8] xref: UniProtKB:Q8NHZ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001986 ! CDC26_HUMAN [Term] id: CCO:B0064190 name: CDC27_HUMAN-Phosphoserine339 def: "Protein CDC27_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:P30260] xref: UniProtKB:P30260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001572 ! CDC27_HUMAN [Term] id: CCO:B0064191 name: CDC37_HUMAN-Phosphoserine377 def: "Protein CDC37_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q16543] xref: UniProtKB:Q16543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001819 ! CDC37_HUMAN [Term] id: CCO:B0064192 name: CDC5L_HUMAN-Phosphothreonine227 def: "Protein CDC5L_HUMAN with the residue 227 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0064193 name: CDC5L_HUMAN-Phosphoserine317 def: "Protein CDC5L_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0064194 name: CDC5L_HUMAN-Phosphothreonine377 def: "Protein CDC5L_HUMAN with the residue 377 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0064195 name: CDC5L_HUMAN-Phosphothreonine415 def: "Protein CDC5L_HUMAN with the residue 415 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0064196 name: CDC5L_HUMAN-Phosphothreonine424 def: "Protein CDC5L_HUMAN with the residue 424 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0064197 name: CDC5L_HUMAN-Phosphothreonine429 def: "Protein CDC5L_HUMAN with the residue 429 substituted with Phosphothreonine" [UniProtKB:Q99459] xref: UniProtKB:Q99459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:B0064198 name: CDC6_HUMAN-Phosphoserine45 def: "Protein CDC6_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q99741] xref: UniProtKB:Q99741 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:B0064199 name: CDC73_HUMAN-Phosphoserine212 def: "Protein CDC73_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q6P1J9] xref: UniProtKB:Q6P1J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001911 ! CDC73_HUMAN [Term] id: CCO:B0064200 name: CDCA2_HUMAN-Phosphoserine121 def: "Protein CDCA2_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064201 name: CDCA2_HUMAN-Phosphoserine127 def: "Protein CDCA2_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064202 name: CDCA2_HUMAN-Phosphoserine129 def: "Protein CDCA2_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064203 name: CDCA2_HUMAN-Phosphoserine132 def: "Protein CDCA2_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064204 name: CDCA2_HUMAN-Phosphoserine310 def: "Protein CDCA2_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064205 name: CDCA2_HUMAN-Phosphothreonine313 def: "Protein CDCA2_HUMAN with the residue 313 substituted with Phosphothreonine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064206 name: CDCA2_HUMAN-Phosphoserine408 def: "Protein CDCA2_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064207 name: CDCA2_HUMAN-Phosphothreonine413 def: "Protein CDCA2_HUMAN with the residue 413 substituted with Phosphothreonine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064208 name: CDCA2_HUMAN-Phosphoserine592 def: "Protein CDCA2_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064209 name: CDCA2_HUMAN-Phosphothreonine604 def: "Protein CDCA2_HUMAN with the residue 604 substituted with Phosphothreonine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064210 name: CDCA2_HUMAN-Phosphoserine727 def: "Protein CDCA2_HUMAN with the residue 727 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064211 name: CDCA2_HUMAN-Phosphoserine757 def: "Protein CDCA2_HUMAN with the residue 757 substituted with Phosphoserine" [UniProtKB:Q69YH5] xref: UniProtKB:Q69YH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001905 ! CDCA2_HUMAN [Term] id: CCO:B0064212 name: CDCA3_HUMAN-Phosphoserine29 def: "Protein CDCA3_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0064213 name: CDCA3_HUMAN-Phosphoserine31 def: "Protein CDCA3_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0064214 name: CDCA3_HUMAN-Phosphothreonine37 def: "Protein CDCA3_HUMAN with the residue 37 substituted with Phosphothreonine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0064215 name: CDCA3_HUMAN-Phosphoserine44 def: "Protein CDCA3_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0064216 name: CDCA3_HUMAN-Phosphoserine64 def: "Protein CDCA3_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0064217 name: CDCA3_HUMAN-Phosphothreonine76 def: "Protein CDCA3_HUMAN with the residue 76 substituted with Phosphothreonine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0064218 name: CDCA3_HUMAN-Phosphoserine87 def: "Protein CDCA3_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q99618] xref: UniProtKB:Q99618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002076 ! CDCA3_HUMAN [Term] id: CCO:B0064219 name: CDCA5_HUMAN-Phosphoserine29 def: "Protein CDCA5_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064220 name: CDCA5_HUMAN-Phosphoserine33 def: "Protein CDCA5_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064221 name: CDCA5_HUMAN-Phosphoserine35 def: "Protein CDCA5_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064222 name: CDCA5_HUMAN-Phosphoserine83 def: "Protein CDCA5_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064223 name: CDCA5_HUMAN-Phosphothreonine105 def: "Protein CDCA5_HUMAN with the residue 105 substituted with Phosphothreonine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064224 name: CDCA5_HUMAN-Phosphothreonine111 def: "Protein CDCA5_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000538 ! cohesin complex relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064225 name: CDCA5_HUMAN-Phosphothreonine115 def: "Protein CDCA5_HUMAN with the residue 115 substituted with Phosphothreonine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064226 name: CDCA5_HUMAN-Phosphoserine209 def: "Protein CDCA5_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q96FF9] xref: UniProtKB:Q96FF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002038 ! CDCA5_HUMAN [Term] id: CCO:B0064227 name: CDGAP_HUMAN-Phosphothreonine789 def: "Protein CDGAP_HUMAN with the residue 789 substituted with Phosphothreonine" [UniProtKB:Q2M1Z3] comment: By similarity xref: UniProtKB:Q2M1Z3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056207 ! CDGAP_HUMAN [Term] id: CCO:B0064228 name: CDGAP_HUMAN-Phosphoserine1105 def: "Protein CDGAP_HUMAN with the residue 1105 substituted with Phosphoserine" [UniProtKB:Q2M1Z3] comment: By similarity xref: UniProtKB:Q2M1Z3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056207 ! CDGAP_HUMAN [Term] id: CCO:B0064229 name: CDGAP_HUMAN-Phosphoserine1106 def: "Protein CDGAP_HUMAN with the residue 1106 substituted with Phosphoserine" [UniProtKB:Q2M1Z3] comment: By similarity xref: UniProtKB:Q2M1Z3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0056207 ! CDGAP_HUMAN [Term] id: CCO:B0064230 name: CDN1B_HUMAN-Phosphotyrosine74 def: "Protein CDN1B_HUMAN with the residue 74 substituted with Phosphotyrosine" [UniProtKB:P46527] comment: by SRC; xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0064231 name: CDN1B_HUMAN-Phosphotyrosine88 def: "Protein CDN1B_HUMAN with the residue 88 substituted with Phosphotyrosine" [UniProtKB:P46527] comment: by ABL, LYN and SRC; xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0064232 name: CDN1B_HUMAN-Phosphotyrosine89 def: "Protein CDN1B_HUMAN with the residue 89 substituted with Phosphotyrosine" [UniProtKB:P46527] xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0064233 name: CDN1B_HUMAN-Phosphothreonine157 def: "Protein CDN1B_HUMAN with the residue 157 substituted with Phosphothreonine" [UniProtKB:P46527] comment: by PKB/AKT1; xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0064234 name: CDN1B_HUMAN-Phosphothreonine187 def: "Protein CDN1B_HUMAN with the residue 187 substituted with Phosphothreonine" [UniProtKB:P46527] comment: by PKB/AKT1 and CDK2; xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0064235 name: CDN1B_HUMAN-Phosphothreonine198 def: "Protein CDN1B_HUMAN with the residue 198 substituted with Phosphothreonine" [UniProtKB:P46527] comment: by PKB/AKT1; RPS6KA4 and RPS6KA5; xref: UniProtKB:P46527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:B0064236 name: CDN1C_HUMAN-Phosphoserine268 def: "Protein CDN1C_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:P49918] xref: UniProtKB:P49918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001640 ! CDN1C_HUMAN [Term] id: CCO:B0064237 name: CDT1_HUMAN-Phosphothreonine29 def: "Protein CDT1_HUMAN with the residue 29 substituted with Phosphothreonine" [UniProtKB:Q9H211] xref: UniProtKB:Q9H211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:B0064238 name: CDT1_HUMAN-Phosphoserine31 def: "Protein CDT1_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q9H211] xref: UniProtKB:Q9H211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:B0064239 name: CDT1_HUMAN-Phosphoserine372 def: "Protein CDT1_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q9H211] xref: UniProtKB:Q9H211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:B0064240 name: CDT1_HUMAN-Phosphoserine394 def: "Protein CDT1_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q9H211] xref: UniProtKB:Q9H211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:B0064241 name: CDV3_HUMAN-N-acetylalanine2 def: "Protein CDV3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9UKY7] comment: By similarity xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064242 name: CDV3_HUMAN-Phosphothreonine4 def: "Protein CDV3_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:Q9UKY7] comment: By similarity xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064243 name: CDV3_HUMAN-Phosphoserine8 def: "Protein CDV3_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q9UKY7] comment: By similarity xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064244 name: CDV3_HUMAN-Phosphoserine25 def: "Protein CDV3_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q9UKY7] xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064245 name: CDV3_HUMAN-Phosphotyrosine95 def: "Protein CDV3_HUMAN with the residue 95 substituted with Phosphotyrosine" [UniProtKB:Q9UKY7] xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064246 name: CDV3_HUMAN-Phosphothreonine182 def: "Protein CDV3_HUMAN with the residue 182 substituted with Phosphothreonine" [UniProtKB:Q9UKY7] xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064247 name: CDV3_HUMAN-Phosphotyrosine190 def: "Protein CDV3_HUMAN with the residue 190 substituted with Phosphotyrosine" [UniProtKB:Q9UKY7] xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064248 name: CDV3_HUMAN-Phosphoserine197 def: "Protein CDV3_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q9UKY7] xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064249 name: CDV3_HUMAN-Phosphoserine216 def: "Protein CDV3_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q9UKY7] xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064250 name: CDV3_HUMAN-Phosphotyrosine244 def: "Protein CDV3_HUMAN with the residue 244 substituted with Phosphotyrosine" [UniProtKB:Q9UKY7] xref: UniProtKB:Q9UKY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059209 ! CDV3_HUMAN [Term] id: CCO:B0064251 name: CEBPZ_HUMAN-Phosphoserine973 def: "Protein CEBPZ_HUMAN with the residue 973 substituted with Phosphoserine" [UniProtKB:Q03701] xref: UniProtKB:Q03701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024821 ! CEBPZ_HUMAN [Term] id: CCO:B0064252 name: CEBPZ_HUMAN-Phosphoserine978 def: "Protein CEBPZ_HUMAN with the residue 978 substituted with Phosphoserine" [UniProtKB:Q03701] xref: UniProtKB:Q03701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024821 ! CEBPZ_HUMAN [Term] id: CCO:B0064253 name: CELR1_HUMAN-3-hydroxyasparagine1666 def: "Protein CELR1_HUMAN with the residue 1666 substituted with 3-hydroxyasparagine" [UniProtKB:Q9NYQ6] comment: Potential xref: UniProtKB:Q9NYQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058968 ! CELR1_HUMAN [Term] id: CCO:B0064254 name: CELR1_HUMAN-3-hydroxyaspartate1889 def: "Protein CELR1_HUMAN with the residue 1889 substituted with 3-hydroxyaspartate" [UniProtKB:Q9NYQ6] comment: Potential xref: UniProtKB:Q9NYQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058968 ! CELR1_HUMAN [Term] id: CCO:B0064255 name: CELR1_HUMAN-Phosphoserine2761 def: "Protein CELR1_HUMAN with the residue 2761 substituted with Phosphoserine" [UniProtKB:Q9NYQ6] xref: UniProtKB:Q9NYQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058968 ! CELR1_HUMAN [Term] id: CCO:B0064256 name: CELR1_HUMAN-Phosphoserine2764 def: "Protein CELR1_HUMAN with the residue 2764 substituted with Phosphoserine" [UniProtKB:Q9NYQ6] xref: UniProtKB:Q9NYQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058968 ! CELR1_HUMAN [Term] id: CCO:B0064257 name: CENB2_HUMAN-Phosphoserine379 def: "Protein CENB2_HUMAN with the residue 379 substituted with Phosphoserine" [UniProtKB:Q15057] xref: UniProtKB:Q15057 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033904 ! CENB2_HUMAN [Term] id: CCO:B0064258 name: CENB2_HUMAN-Phosphoserine384 def: "Protein CENB2_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q15057] xref: UniProtKB:Q15057 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033904 ! CENB2_HUMAN [Term] id: CCO:B0064259 name: CEND2_HUMAN-Phosphotyrosine191 def: "Protein CEND2_HUMAN with the residue 191 substituted with Phosphotyrosine" [UniProtKB:Q96P48] xref: UniProtKB:Q96P48 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001670 ! phosphatidylinositol-3,4,5-triphosphate binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0002052 ! CEND2_HUMAN [Term] id: CCO:B0064260 name: CEND2_HUMAN-Phosphoserine1195 def: "Protein CEND2_HUMAN with the residue 1195 substituted with Phosphoserine" [UniProtKB:Q96P48] xref: UniProtKB:Q96P48 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002052 ! CEND2_HUMAN [Term] id: CCO:B0064261 name: CEND3_HUMAN-Phosphotyrosine1403 def: "Protein CEND3_HUMAN with the residue 1403 substituted with Phosphotyrosine" [UniProtKB:Q8WWN8] comment: By similarity xref: UniProtKB:Q8WWN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024597 ! CEND3_HUMAN [Term] id: CCO:B0064262 name: CEND3_HUMAN-Phosphotyrosine1408 def: "Protein CEND3_HUMAN with the residue 1408 substituted with Phosphotyrosine" [UniProtKB:Q8WWN8] comment: By similarity xref: UniProtKB:Q8WWN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024597 ! CEND3_HUMAN [Term] id: CCO:B0064263 name: CEND3_HUMAN-Phosphoserine1444 def: "Protein CEND3_HUMAN with the residue 1444 substituted with Phosphoserine" [UniProtKB:Q8WWN8] xref: UniProtKB:Q8WWN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024597 ! CEND3_HUMAN [Term] id: CCO:B0064264 name: CENG1_HUMAN-Phosphoserine149 def: "Protein CENG1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q99490] comment: By similarity xref: UniProtKB:Q99490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058417 ! CENG1_HUMAN [Term] id: CCO:B0064265 name: CENG1_HUMAN-Phosphoserine267 def: "Protein CENG1_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q99490] comment: By similarity xref: UniProtKB:Q99490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058417 ! CENG1_HUMAN [Term] id: CCO:B0064266 name: CENG1_HUMAN-Phosphoserine638 def: "Protein CENG1_HUMAN with the residue 638 substituted with Phosphoserine" [UniProtKB:Q99490] comment: By similarity xref: UniProtKB:Q99490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058417 ! CENG1_HUMAN [Term] id: CCO:B0064267 name: CENG1_HUMAN-Phosphoserine808 def: "Protein CENG1_HUMAN with the residue 808 substituted with Phosphoserine" [UniProtKB:Q99490] comment: By similarity xref: UniProtKB:Q99490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058417 ! CENG1_HUMAN [Term] id: CCO:B0064268 name: CENG1_HUMAN-Phosphoserine865 def: "Protein CENG1_HUMAN with the residue 865 substituted with Phosphoserine" [UniProtKB:Q99490] comment: By similarity xref: UniProtKB:Q99490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058417 ! CENG1_HUMAN [Term] id: CCO:B0064269 name: CENG1_HUMAN-Phosphoserine927 def: "Protein CENG1_HUMAN with the residue 927 substituted with Phosphoserine" [UniProtKB:Q99490] comment: By similarity xref: UniProtKB:Q99490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058417 ! CENG1_HUMAN [Term] id: CCO:B0064270 name: CENG2_HUMAN-Phosphoserine315 def: "Protein CENG2_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q9UPQ3] xref: UniProtKB:Q9UPQ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059263 ! CENG2_HUMAN [Term] id: CCO:B0064271 name: CENG2_HUMAN-Phosphothreonine836 def: "Protein CENG2_HUMAN with the residue 836 substituted with Phosphothreonine" [UniProtKB:Q9UPQ3] xref: UniProtKB:Q9UPQ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059263 ! CENG2_HUMAN [Term] id: CCO:B0064272 name: CENG3_HUMAN-Phosphothreonine324 def: "Protein CENG3_HUMAN with the residue 324 substituted with Phosphothreonine" [UniProtKB:Q96P47] xref: UniProtKB:Q96P47 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058317 ! CENG3_HUMAN [Term] id: CCO:B0064273 name: CENG3_HUMAN-Phosphothreonine326 def: "Protein CENG3_HUMAN with the residue 326 substituted with Phosphothreonine" [UniProtKB:Q96P47] xref: UniProtKB:Q96P47 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058317 ! CENG3_HUMAN [Term] id: CCO:B0064274 name: CENG3_HUMAN-Phosphoserine336 def: "Protein CENG3_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:Q96P47] xref: UniProtKB:Q96P47 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058317 ! CENG3_HUMAN [Term] id: CCO:B0064275 name: CENG3_HUMAN-Phosphoserine443 def: "Protein CENG3_HUMAN with the residue 443 substituted with Phosphoserine" [UniProtKB:Q96P47] xref: UniProtKB:Q96P47 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058317 ! CENG3_HUMAN [Term] id: CCO:B0064276 name: CENPC_HUMAN-Phosphoserine261 def: "Protein CENPC_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0064277 name: CENPC_HUMAN-Phosphoserine763 def: "Protein CENPC_HUMAN with the residue 763 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0064278 name: CENPC_HUMAN-Phosphoserine773 def: "Protein CENPC_HUMAN with the residue 773 substituted with Phosphoserine" [UniProtKB:Q03188] xref: UniProtKB:Q03188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:B0064279 name: CENPE_HUMAN-Phosphoserine2647 def: "Protein CENPE_HUMAN with the residue 2647 substituted with Phosphoserine" [UniProtKB:Q02224] xref: UniProtKB:Q02224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001715 ! CENPE_HUMAN [Term] id: CCO:B0064280 name: CENPF_HUMAN-Phosphoserine106 def: "Protein CENPF_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0064281 name: CENPF_HUMAN-Phosphothreonine144 def: "Protein CENPF_HUMAN with the residue 144 substituted with Phosphothreonine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0064282 name: CENPF_HUMAN-Phosphoserine834 def: "Protein CENPF_HUMAN with the residue 834 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0064283 name: CENPF_HUMAN-Phosphoserine1248 def: "Protein CENPF_HUMAN with the residue 1248 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0064284 name: CENPF_HUMAN-Phosphoserine1748 def: "Protein CENPF_HUMAN with the residue 1748 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0064285 name: CENPF_HUMAN-Phosphoserine2512 def: "Protein CENPF_HUMAN with the residue 2512 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0064286 name: CENPF_HUMAN-Phosphoserine3122 def: "Protein CENPF_HUMAN with the residue 3122 substituted with Phosphoserine" [UniProtKB:P49454] xref: UniProtKB:P49454 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001629 ! CENPF_HUMAN [Term] id: CCO:B0064287 name: CENPR_HUMAN-Phosphoserine17 def: "Protein CENPR_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q13352] xref: UniProtKB:Q13352 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:B0064288 name: CENPU_HUMAN-Phosphothreonine78 def: "Protein CENPU_HUMAN with the residue 78 substituted with Phosphothreonine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064289 name: CENPU_HUMAN-Phosphoserine94 def: "Protein CENPU_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064290 name: CENPU_HUMAN-Phosphoserine108 def: "Protein CENPU_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064291 name: CENPU_HUMAN-Phosphothreonine110 def: "Protein CENPU_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064292 name: CENPU_HUMAN-Phosphoserine111 def: "Protein CENPU_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064293 name: CENPU_HUMAN-Phosphoserine136 def: "Protein CENPU_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064294 name: CENPU_HUMAN-Phosphoserine139 def: "Protein CENPU_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064295 name: CENPU_HUMAN-Phosphoserine141 def: "Protein CENPU_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064296 name: CENPU_HUMAN-Phosphoserine229 def: "Protein CENPU_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:Q71F23] xref: UniProtKB:Q71F23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057096 ! CENPU_HUMAN [Term] id: CCO:B0064297 name: CEP55_HUMAN-Phosphothreonine430 def: "Protein CEP55_HUMAN with the residue 430 substituted with Phosphothreonine" [UniProtKB:Q53EZ4] xref: UniProtKB:Q53EZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001837 ! CEP55_HUMAN [Term] id: CCO:B0064298 name: CEP76_HUMAN-Phosphoserine83 def: "Protein CEP76_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q8TAP6] xref: UniProtKB:Q8TAP6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005244 ! CEP76_HUMAN [Term] id: CCO:B0064299 name: CFDP1_HUMAN-Phosphoserine116 def: "Protein CFDP1_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q9UEE9] xref: UniProtKB:Q9UEE9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059107 ! CFDP1_HUMAN [Term] id: CCO:B0064300 name: CFDP1_HUMAN-Phosphoserine250 def: "Protein CFDP1_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:Q9UEE9] xref: UniProtKB:Q9UEE9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0059107 ! CFDP1_HUMAN [Term] id: CCO:B0064301 name: CGBP1_HUMAN-Phosphoserine164 def: "Protein CGBP1_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q9UFW8] xref: UniProtKB:Q9UFW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059117 ! CGBP1_HUMAN [Term] id: CCO:B0064302 name: CH10_HUMAN-Phosphotyrosine88 def: "Protein CH10_HUMAN with the residue 88 substituted with Phosphotyrosine" [UniProtKB:P61604] xref: UniProtKB:P61604 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_function CCO:F0008056 ! chaperone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0006092 ! CH10_HUMAN [Term] id: CCO:B0064303 name: CHD3_HUMAN-Phosphoserine1361 def: "Protein CHD3_HUMAN with the residue 1361 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0064304 name: CHD3_HUMAN-Phosphoserine1364 def: "Protein CHD3_HUMAN with the residue 1364 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0064305 name: CHD3_HUMAN-Phosphoserine1367 def: "Protein CHD3_HUMAN with the residue 1367 substituted with Phosphoserine" [UniProtKB:Q12873] xref: UniProtKB:Q12873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:B0064306 name: CHD4_HUMAN-Phosphoserine103 def: "Protein CHD4_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064307 name: CHD4_HUMAN-Phosphoserine428 def: "Protein CHD4_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064308 name: CHD4_HUMAN-Phosphoserine515 def: "Protein CHD4_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064309 name: CHD4_HUMAN-Phosphothreonine517 def: "Protein CHD4_HUMAN with the residue 517 substituted with Phosphothreonine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064310 name: CHD4_HUMAN-Phosphothreonine529 def: "Protein CHD4_HUMAN with the residue 529 substituted with Phosphothreonine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064311 name: CHD4_HUMAN-Phosphoserine531 def: "Protein CHD4_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064312 name: CHD4_HUMAN-Phosphoserine1308 def: "Protein CHD4_HUMAN with the residue 1308 substituted with Phosphoserine" [UniProtKB:Q14839] comment: By similarity xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064313 name: CHD4_HUMAN-Phosphoserine1349 def: "Protein CHD4_HUMAN with the residue 1349 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064314 name: CHD4_HUMAN-Phosphoserine1531 def: "Protein CHD4_HUMAN with the residue 1531 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064315 name: CHD4_HUMAN-Phosphoserine1535 def: "Protein CHD4_HUMAN with the residue 1535 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064316 name: CHD4_HUMAN-Phosphoserine1537 def: "Protein CHD4_HUMAN with the residue 1537 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064317 name: CHD4_HUMAN-Phosphothreonine1540 def: "Protein CHD4_HUMAN with the residue 1540 substituted with Phosphothreonine" [UniProtKB:Q14839] comment: By similarity xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064318 name: CHD4_HUMAN-Phosphothreonine1542 def: "Protein CHD4_HUMAN with the residue 1542 substituted with Phosphothreonine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064319 name: CHD4_HUMAN-Phosphothreonine1545 def: "Protein CHD4_HUMAN with the residue 1545 substituted with Phosphothreonine" [UniProtKB:Q14839] comment: By similarity xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064320 name: CHD4_HUMAN-Phosphothreonine1549 def: "Protein CHD4_HUMAN with the residue 1549 substituted with Phosphothreonine" [UniProtKB:Q14839] comment: By similarity xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064321 name: CHD4_HUMAN-Phosphoserine1570 def: "Protein CHD4_HUMAN with the residue 1570 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064322 name: CHD4_HUMAN-Phosphoserine1576 def: "Protein CHD4_HUMAN with the residue 1576 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064323 name: CHD4_HUMAN-Phosphoserine1602 def: "Protein CHD4_HUMAN with the residue 1602 substituted with Phosphoserine" [UniProtKB:Q14839] xref: UniProtKB:Q14839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056018 ! CHD4_HUMAN [Term] id: CCO:B0064324 name: CHD6_HUMAN-Phosphoserine53 def: "Protein CHD6_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q8TD26] xref: UniProtKB:Q8TD26 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057921 ! CHD6_HUMAN [Term] id: CCO:B0064325 name: CHD6_HUMAN-Phosphoserine1069 def: "Protein CHD6_HUMAN with the residue 1069 substituted with Phosphoserine" [UniProtKB:Q8TD26] xref: UniProtKB:Q8TD26 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057921 ! CHD6_HUMAN [Term] id: CCO:B0064326 name: CHD6_HUMAN-Phosphoserine1073 def: "Protein CHD6_HUMAN with the residue 1073 substituted with Phosphoserine" [UniProtKB:Q8TD26] xref: UniProtKB:Q8TD26 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057921 ! CHD6_HUMAN [Term] id: CCO:B0064327 name: CHD6_HUMAN-Phosphoserine2041 def: "Protein CHD6_HUMAN with the residue 2041 substituted with Phosphoserine" [UniProtKB:Q8TD26] xref: UniProtKB:Q8TD26 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057921 ! CHD6_HUMAN [Term] id: CCO:B0064328 name: CHD7_HUMAN-Phosphoserine2254 def: "Protein CHD7_HUMAN with the residue 2254 substituted with Phosphoserine" [UniProtKB:Q9P2D1] xref: UniProtKB:Q9P2D1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059056 ! CHD7_HUMAN [Term] id: CCO:B0064329 name: CHD7_HUMAN-Phosphoserine2255 def: "Protein CHD7_HUMAN with the residue 2255 substituted with Phosphoserine" [UniProtKB:Q9P2D1] xref: UniProtKB:Q9P2D1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059056 ! CHD7_HUMAN [Term] id: CCO:B0064330 name: CHD7_HUMAN-Phosphothreonine2350 def: "Protein CHD7_HUMAN with the residue 2350 substituted with Phosphothreonine" [UniProtKB:Q9P2D1] xref: UniProtKB:Q9P2D1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059056 ! CHD7_HUMAN [Term] id: CCO:B0064331 name: CHD7_HUMAN-Phosphoserine2356 def: "Protein CHD7_HUMAN with the residue 2356 substituted with Phosphoserine" [UniProtKB:Q9P2D1] xref: UniProtKB:Q9P2D1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059056 ! CHD7_HUMAN [Term] id: CCO:B0064332 name: CHD7_HUMAN-Phosphoserine2533 def: "Protein CHD7_HUMAN with the residue 2533 substituted with Phosphoserine" [UniProtKB:Q9P2D1] xref: UniProtKB:Q9P2D1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059056 ! CHD7_HUMAN [Term] id: CCO:B0064333 name: CHD7_HUMAN-Phosphoserine2559 def: "Protein CHD7_HUMAN with the residue 2559 substituted with Phosphoserine" [UniProtKB:Q9P2D1] xref: UniProtKB:Q9P2D1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059056 ! CHD7_HUMAN [Term] id: CCO:B0064334 name: CHD8_HUMAN-Phosphoserine271 def: "Protein CHD8_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0064335 name: CHD8_HUMAN-Phosphoserine274 def: "Protein CHD8_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0064336 name: CHD8_HUMAN-Phosphoserine283 def: "Protein CHD8_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0064337 name: CHD8_HUMAN-Phosphoserine1697 def: "Protein CHD8_HUMAN with the residue 1697 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0064338 name: CHD8_HUMAN-Phosphoserine1716 def: "Protein CHD8_HUMAN with the residue 1716 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0064339 name: CHD8_HUMAN-Phosphoserine1729 def: "Protein CHD8_HUMAN with the residue 1729 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0064340 name: CHD8_HUMAN-Phosphoserine1767 def: "Protein CHD8_HUMAN with the residue 1767 substituted with Phosphoserine" [UniProtKB:Q9HCK8] xref: UniProtKB:Q9HCK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:B0064341 name: CHD9_HUMAN-Phosphoserine550 def: "Protein CHD9_HUMAN with the residue 550 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064342 name: CHD9_HUMAN-Phosphoserine611 def: "Protein CHD9_HUMAN with the residue 611 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064343 name: CHD9_HUMAN-Phosphoserine612 def: "Protein CHD9_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064344 name: CHD9_HUMAN-Phosphoserine616 def: "Protein CHD9_HUMAN with the residue 616 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064345 name: CHD9_HUMAN-Phosphothreonine625 def: "Protein CHD9_HUMAN with the residue 625 substituted with Phosphothreonine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064346 name: CHD9_HUMAN-Phosphotyrosine645 def: "Protein CHD9_HUMAN with the residue 645 substituted with Phosphotyrosine" [UniProtKB:Q3L8U1] comment: By similarity xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064347 name: CHD9_HUMAN-Phosphoserine1468 def: "Protein CHD9_HUMAN with the residue 1468 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064348 name: CHD9_HUMAN-Phosphoserine1472 def: "Protein CHD9_HUMAN with the residue 1472 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064349 name: CHD9_HUMAN-Phosphothreonine2013 def: "Protein CHD9_HUMAN with the residue 2013 substituted with Phosphothreonine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064350 name: CHD9_HUMAN-Phosphoserine2026 def: "Protein CHD9_HUMAN with the residue 2026 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064351 name: CHD9_HUMAN-Phosphoserine2879 def: "Protein CHD9_HUMAN with the residue 2879 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064352 name: CHD9_HUMAN-Phosphoserine2883 def: "Protein CHD9_HUMAN with the residue 2883 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064353 name: CHD9_HUMAN-Phosphoserine2891 def: "Protein CHD9_HUMAN with the residue 2891 substituted with Phosphoserine" [UniProtKB:Q3L8U1] xref: UniProtKB:Q3L8U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056261 ! CHD9_HUMAN [Term] id: CCO:B0064354 name: CHMP5_HUMAN-Phosphoserine219 def: "Protein CHMP5_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q9NZZ3] xref: UniProtKB:Q9NZZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059023 ! CHMP5_HUMAN [Term] id: CCO:B0064355 name: CIDEB_HUMAN-Phosphoserine17 def: "Protein CIDEB_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q9UHD4] comment: By similarity xref: UniProtKB:Q9UHD4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0059137 ! CIDEB_HUMAN [Term] id: CCO:B0064356 name: CIP4_HUMAN-Phosphoserine296 def: "Protein CIP4_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q15642] xref: UniProtKB:Q15642 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056090 ! CIP4_HUMAN [Term] id: CCO:B0064357 name: CIP4_HUMAN-Phosphoserine299 def: "Protein CIP4_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:Q15642] xref: UniProtKB:Q15642 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056090 ! CIP4_HUMAN [Term] id: CCO:B0064358 name: CIP4_HUMAN-Phosphoserine335 def: "Protein CIP4_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q15642] xref: UniProtKB:Q15642 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056090 ! CIP4_HUMAN [Term] id: CCO:B0064359 name: CIP4_HUMAN-Phosphoserine351 def: "Protein CIP4_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q15642] xref: UniProtKB:Q15642 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056090 ! CIP4_HUMAN [Term] id: CCO:B0064360 name: CIR_HUMAN-Phosphoserine202 def: "Protein CIR_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q86X95] xref: UniProtKB:Q86X95 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:B0064361 name: CJ119_HUMAN-Phosphoserine298 def: "Protein CJ119_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:Q9BTE3] xref: UniProtKB:Q9BTE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005262 ! CJ119_HUMAN [Term] id: CCO:B0064362 name: CK5P2_HUMAN-Phosphoserine1887 def: "Protein CK5P2_HUMAN with the residue 1887 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0064363 name: CK5P2_HUMAN-Phosphoserine1893 def: "Protein CK5P2_HUMAN with the residue 1893 substituted with Phosphoserine" [UniProtKB:Q96SN8] xref: UniProtKB:Q96SN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:B0064364 name: CKAP2_HUMAN-Phosphoserine595 def: "Protein CKAP2_HUMAN with the residue 595 substituted with Phosphoserine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0064365 name: CKAP2_HUMAN-Phosphothreonine596 def: "Protein CKAP2_HUMAN with the residue 596 substituted with Phosphothreonine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0064366 name: CKAP2_HUMAN-Phosphotyrosine599 def: "Protein CKAP2_HUMAN with the residue 599 substituted with Phosphotyrosine" [UniProtKB:Q8WWK9] xref: UniProtKB:Q8WWK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002006 ! CKAP2_HUMAN [Term] id: CCO:B0064367 name: CKAP4_HUMAN-Phosphoserine312 def: "Protein CKAP4_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q07065] xref: UniProtKB:Q07065 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001534 ! ER-Golgi intermediate compartment membrane relationship: transformation_of CCO:B0005829 ! CKAP4_HUMAN [Term] id: CCO:B0064368 name: CKAP4_HUMAN-Phosphothreonine316 def: "Protein CKAP4_HUMAN with the residue 316 substituted with Phosphothreonine" [UniProtKB:Q07065] xref: UniProtKB:Q07065 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005829 ! CKAP4_HUMAN [Term] id: CCO:B0064369 name: CKAP4_HUMAN-Phosphoserine330 def: "Protein CKAP4_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q07065] xref: UniProtKB:Q07065 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005829 ! CKAP4_HUMAN [Term] id: CCO:B0064370 name: CLAP1_HUMAN-Phosphoserine647 def: "Protein CLAP1_HUMAN with the residue 647 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0064371 name: CLAP1_HUMAN-Phosphoserine649 def: "Protein CLAP1_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0064372 name: CLAP1_HUMAN-Phosphothreonine656 def: "Protein CLAP1_HUMAN with the residue 656 substituted with Phosphothreonine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0005864 ! kinetochore binding relationship: has_function CCO:F0008033 ! microtubule plus-end binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000396 ! kinetochore microtubule relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000436 ! spindle microtubule relationship: located_in CCO:C0000439 ! cytoplasmic microtubule relationship: located_in CCO:C0001096 ! cortical microtubule cytoskeleton relationship: located_in CCO:C0001299 ! centrosomal corona relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0064373 name: CLAP1_HUMAN-Phosphoserine688 def: "Protein CLAP1_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0064374 name: CLAP1_HUMAN-Phosphoserine695 def: "Protein CLAP1_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0064375 name: CLAP1_HUMAN-Phosphothreonine711 def: "Protein CLAP1_HUMAN with the residue 711 substituted with Phosphothreonine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0064376 name: CLAP1_HUMAN-Phosphoserine714 def: "Protein CLAP1_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:Q7Z460] xref: UniProtKB:Q7Z460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:B0064377 name: CLC1B_HUMAN-Phosphotyrosine7 def: "Protein CLC1B_HUMAN with the residue 7 substituted with Phosphotyrosine" [UniProtKB:Q9P126] xref: UniProtKB:Q9P126 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059037 ! CLC1B_HUMAN [Term] id: CCO:B0064378 name: CLC7A_HUMAN-Phosphotyrosine15 def: "Protein CLC7A_HUMAN with the residue 15 substituted with Phosphotyrosine" [UniProtKB:Q9BXN2] comment: By similarity xref: UniProtKB:Q9BXN2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058561 ! CLC7A_HUMAN [Term] id: CCO:B0064379 name: CLC7A_HUMAN-Phosphoserine160 def: "Protein CLC7A_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:Q9BXN2] xref: UniProtKB:Q9BXN2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058561 ! CLC7A_HUMAN [Term] id: CCO:B0064380 name: CLIC1_HUMAN-N-acetylalanine2 def: "Protein CLIC1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O00299] xref: UniProtKB:O00299 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054309 ! CLIC1_HUMAN [Term] id: CCO:B0064381 name: CLIC1_HUMAN-Phosphotyrosine233 def: "Protein CLIC1_HUMAN with the residue 233 substituted with Phosphotyrosine" [UniProtKB:O00299] comment: By similarity xref: UniProtKB:O00299 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054309 ! CLIC1_HUMAN [Term] id: CCO:B0064382 name: CLIC4_HUMAN-N-acetylalanine2 def: "Protein CLIC4_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y696] xref: UniProtKB:Q9Y696 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001515 ! voltage-gated chloride channel activity relationship: has_function CCO:F0001522 ! chloride channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004658 ! chloride ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000459 ! microvillus relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0059402 ! CLIC4_HUMAN [Term] id: CCO:B0064383 name: CLIP1_HUMAN-Phosphothreonine45 def: "Protein CLIP1_HUMAN with the residue 45 substituted with Phosphothreonine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0064384 name: CLIP1_HUMAN-Phosphoserine48 def: "Protein CLIP1_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0064385 name: CLIP1_HUMAN-Phosphothreonine140 def: "Protein CLIP1_HUMAN with the residue 140 substituted with Phosphothreonine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0064386 name: CLIP1_HUMAN-Phosphoserine143 def: "Protein CLIP1_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0064387 name: CLIP1_HUMAN-Phosphoserine147 def: "Protein CLIP1_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0064388 name: CLIP1_HUMAN-Phosphoserine197 def: "Protein CLIP1_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:P30622] xref: UniProtKB:P30622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001580 ! CLIP1_HUMAN [Term] id: CCO:B0064389 name: CLN3_HUMAN-Phosphoserine12 def: "Protein CLN3_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q13286] xref: UniProtKB:Q13286 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055893 ! CLN3_HUMAN [Term] id: CCO:B0064390 name: CLN3_HUMAN-Phosphoserine14 def: "Protein CLN3_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q13286] xref: UniProtKB:Q13286 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055893 ! CLN3_HUMAN [Term] id: CCO:B0064391 name: CLN6_HUMAN-Phosphoserine31 def: "Protein CLN6_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q9NWW5] xref: UniProtKB:Q9NWW5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058942 ! CLN6_HUMAN [Term] id: CCO:B0064392 name: CLSPN_HUMAN-Phosphoserine83 def: "Protein CLSPN_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064393 name: CLSPN_HUMAN-Phosphoserine225 def: "Protein CLSPN_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064394 name: CLSPN_HUMAN-Phosphoserine720 def: "Protein CLSPN_HUMAN with the residue 720 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064395 name: CLSPN_HUMAN-Phosphothreonine724 def: "Protein CLSPN_HUMAN with the residue 724 substituted with Phosphothreonine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064396 name: CLSPN_HUMAN-Phosphoserine808 def: "Protein CLSPN_HUMAN with the residue 808 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064397 name: CLSPN_HUMAN-Phosphoserine810 def: "Protein CLSPN_HUMAN with the residue 810 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064398 name: CLSPN_HUMAN-Phosphoserine1012 def: "Protein CLSPN_HUMAN with the residue 1012 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064399 name: CLSPN_HUMAN-Phosphoserine1018 def: "Protein CLSPN_HUMAN with the residue 1018 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064400 name: CLSPN_HUMAN-Phosphoserine1020 def: "Protein CLSPN_HUMAN with the residue 1020 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064401 name: CLSPN_HUMAN-Phosphoserine1156 def: "Protein CLSPN_HUMAN with the residue 1156 substituted with Phosphoserine" [UniProtKB:Q9HAW4] xref: UniProtKB:Q9HAW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002142 ! CLSPN_HUMAN [Term] id: CCO:B0064402 name: CMTA1_HUMAN-Phosphotyrosine117 def: "Protein CMTA1_HUMAN with the residue 117 substituted with Phosphotyrosine" [UniProtKB:Q9Y6Y1] xref: UniProtKB:Q9Y6Y1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059420 ! CMTA1_HUMAN [Term] id: CCO:B0064403 name: CN043_HUMAN-Phosphoserine461 def: "Protein CN043_HUMAN with the residue 461 substituted with Phosphoserine" [UniProtKB:Q6PJG2] xref: UniProtKB:Q6PJG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056920 ! CN043_HUMAN [Term] id: CCO:B0064404 name: CN043_HUMAN-Phosphoserine661 def: "Protein CN043_HUMAN with the residue 661 substituted with Phosphoserine" [UniProtKB:Q6PJG2] xref: UniProtKB:Q6PJG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056920 ! CN043_HUMAN [Term] id: CCO:B0064405 name: CN043_HUMAN-Phosphoserine700 def: "Protein CN043_HUMAN with the residue 700 substituted with Phosphoserine" [UniProtKB:Q6PJG2] xref: UniProtKB:Q6PJG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056920 ! CN043_HUMAN [Term] id: CCO:B0064406 name: CN043_HUMAN-Phosphothreonine704 def: "Protein CN043_HUMAN with the residue 704 substituted with Phosphothreonine" [UniProtKB:Q6PJG2] xref: UniProtKB:Q6PJG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056920 ! CN043_HUMAN [Term] id: CCO:B0064407 name: CN043_HUMAN-Phosphothreonine715 def: "Protein CN043_HUMAN with the residue 715 substituted with Phosphothreonine" [UniProtKB:Q6PJG2] xref: UniProtKB:Q6PJG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056920 ! CN043_HUMAN [Term] id: CCO:B0064408 name: CN043_HUMAN-Phosphoserine923 def: "Protein CN043_HUMAN with the residue 923 substituted with Phosphoserine" [UniProtKB:Q6PJG2] xref: UniProtKB:Q6PJG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056920 ! CN043_HUMAN [Term] id: CCO:B0064409 name: CND2_HUMAN-Phosphoserine70 def: "Protein CND2_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0064410 name: CND2_HUMAN-Phosphoserine87 def: "Protein CND2_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0064411 name: CND2_HUMAN-Phosphoserine432 def: "Protein CND2_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0064412 name: CND2_HUMAN-Phosphothreonine614 def: "Protein CND2_HUMAN with the residue 614 substituted with Phosphothreonine" [UniProtKB:Q15003] xref: UniProtKB:Q15003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001797 ! CND2_HUMAN [Term] id: CCO:B0064413 name: CND3_HUMAN-Phosphoserine1002 def: "Protein CND3_HUMAN with the residue 1002 substituted with Phosphoserine" [UniProtKB:Q9BPX3] xref: UniProtKB:Q9BPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002092 ! CND3_HUMAN [Term] id: CCO:B0064414 name: CNDD3_HUMAN-Phosphoserine1348 def: "Protein CNDD3_HUMAN with the residue 1348 substituted with Phosphoserine" [UniProtKB:P42695] xref: UniProtKB:P42695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001614 ! CNDD3_HUMAN [Term] id: CCO:B0064415 name: CNDH2_HUMAN-Phosphoserine282 def: "Protein CNDH2_HUMAN with the residue 282 substituted with Phosphoserine" [UniProtKB:Q6IBW4] xref: UniProtKB:Q6IBW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041259 ! CNDH2_HUMAN [Term] id: CCO:B0064416 name: CNKR1_HUMAN-Phosphoserine305 def: "Protein CNKR1_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q969H4] xref: UniProtKB:Q969H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000489 ! cell cortex relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058131 ! CNKR1_HUMAN [Term] id: CCO:B0064417 name: CNKR1_HUMAN-Phosphoserine307 def: "Protein CNKR1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q969H4] xref: UniProtKB:Q969H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058131 ! CNKR1_HUMAN [Term] id: CCO:B0064418 name: CNKR1_HUMAN-Phosphoserine314 def: "Protein CNKR1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:Q969H4] xref: UniProtKB:Q969H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058131 ! CNKR1_HUMAN [Term] id: CCO:B0064419 name: CNKR2_HUMAN-Phosphoserine248 def: "Protein CNKR2_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:Q8WXI2] comment: By similarity xref: UniProtKB:Q8WXI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058022 ! CNKR2_HUMAN [Term] id: CCO:B0064420 name: CNKR2_HUMAN-Phosphoserine325 def: "Protein CNKR2_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:Q8WXI2] comment: By similarity xref: UniProtKB:Q8WXI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058022 ! CNKR2_HUMAN [Term] id: CCO:B0064421 name: CNKR2_HUMAN-Phosphoserine390 def: "Protein CNKR2_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:Q8WXI2] comment: By similarity xref: UniProtKB:Q8WXI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058022 ! CNKR2_HUMAN [Term] id: CCO:B0064422 name: CNKR2_HUMAN-Phosphoserine467 def: "Protein CNKR2_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:Q8WXI2] comment: By similarity xref: UniProtKB:Q8WXI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058022 ! CNKR2_HUMAN [Term] id: CCO:B0064423 name: CNKR2_HUMAN-Phosphothreonine846 def: "Protein CNKR2_HUMAN with the residue 846 substituted with Phosphothreonine" [UniProtKB:Q8WXI2] comment: By similarity xref: UniProtKB:Q8WXI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058022 ! CNKR2_HUMAN [Term] id: CCO:B0064424 name: CNKR2_HUMAN-Phosphoserine908 def: "Protein CNKR2_HUMAN with the residue 908 substituted with Phosphoserine" [UniProtKB:Q8WXI2] comment: By similarity xref: UniProtKB:Q8WXI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058022 ! CNKR2_HUMAN [Term] id: CCO:B0064425 name: CNKR3_HUMAN-Phosphoserine381 def: "Protein CNKR3_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q6P9H4] comment: By similarity xref: UniProtKB:Q6P9H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056898 ! CNKR3_HUMAN [Term] id: CCO:B0064426 name: CNOT2_HUMAN-Phosphothreonine93 def: "Protein CNOT2_HUMAN with the residue 93 substituted with Phosphothreonine" [UniProtKB:Q9NZN8] xref: UniProtKB:Q9NZN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049757 ! CNOT2_HUMAN [Term] id: CCO:B0064427 name: CNOT2_HUMAN-Phosphoserine165 def: "Protein CNOT2_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q9NZN8] xref: UniProtKB:Q9NZN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049757 ! CNOT2_HUMAN [Term] id: CCO:B0064428 name: CNOT3_HUMAN-Phosphoserine299 def: "Protein CNOT3_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:O75175] xref: UniProtKB:O75175 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054611 ! CNOT3_HUMAN [Term] id: CCO:B0064429 name: CNOT4_HUMAN-Phosphoserine71 def: "Protein CNOT4_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:O95628] xref: UniProtKB:O95628 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054775 ! CNOT4_HUMAN [Term] id: CCO:B0064430 name: CNTP1_HUMAN-Phosphoserine1383 def: "Protein CNTP1_HUMAN with the residue 1383 substituted with Phosphoserine" [UniProtKB:P78357] comment: By similarity xref: UniProtKB:P78357 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055641 ! CNTP1_HUMAN [Term] id: CCO:B0064431 name: CO1A2_HUMAN-Pyrrolidone carboxylic acid80 def: "Protein CO1A2_HUMAN with the residue 80 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P08123] comment: By similarity xref: UniProtKB:P08123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054920 ! CO1A2_HUMAN [Term] id: CCO:B0064432 name: CO1A2_HUMAN-Allysine84 def: "Protein CO1A2_HUMAN with the residue 84 substituted with Allysine" [UniProtKB:P08123] xref: UniProtKB:P08123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054920 ! CO1A2_HUMAN [Term] id: CCO:B0064433 name: CO1A2_HUMAN-Hydroxyproline420 def: "Protein CO1A2_HUMAN with the residue 420 substituted with Hydroxyproline" [UniProtKB:P08123] xref: UniProtKB:P08123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054920 ! CO1A2_HUMAN [Term] id: CCO:B0064434 name: CO1A2_HUMAN-Hydroxyproline441 def: "Protein CO1A2_HUMAN with the residue 441 substituted with Hydroxyproline" [UniProtKB:P08123] xref: UniProtKB:P08123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054920 ! CO1A2_HUMAN [Term] id: CCO:B0064435 name: CO1A2_HUMAN-Hydroxyproline444 def: "Protein CO1A2_HUMAN with the residue 444 substituted with Hydroxyproline" [UniProtKB:P08123] xref: UniProtKB:P08123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054920 ! CO1A2_HUMAN [Term] id: CCO:B0064436 name: CO3A1_HUMAN-5-hydroxylysine263 def: "Protein CO3A1_HUMAN with the residue 263 substituted with 5-hydroxylysine" [UniProtKB:P02461] xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064437 name: CO3A1_HUMAN-5-hydroxylysine284 def: "Protein CO3A1_HUMAN with the residue 284 substituted with 5-hydroxylysine" [UniProtKB:P02461] xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064438 name: CO3A1_HUMAN-5-hydroxylysine860 def: "Protein CO3A1_HUMAN with the residue 860 substituted with 5-hydroxylysine" [UniProtKB:P02461] xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064439 name: CO3A1_HUMAN-5-hydroxylysine977 def: "Protein CO3A1_HUMAN with the residue 977 substituted with 5-hydroxylysine" [UniProtKB:P02461] xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064440 name: CO3A1_HUMAN-5-hydroxylysine1094 def: "Protein CO3A1_HUMAN with the residue 1094 substituted with 5-hydroxylysine" [UniProtKB:P02461] comment: partial; xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064441 name: CO3A1_HUMAN-5-hydroxylysine1106 def: "Protein CO3A1_HUMAN with the residue 1106 substituted with 5-hydroxylysine" [UniProtKB:P02461] xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064442 name: CO3A1_HUMAN-Phosphotyrosine1378 def: "Protein CO3A1_HUMAN with the residue 1378 substituted with Phosphotyrosine" [UniProtKB:P02461] xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064443 name: CO3A1_HUMAN-Phosphoserine1383 def: "Protein CO3A1_HUMAN with the residue 1383 substituted with Phosphoserine" [UniProtKB:P02461] xref: UniProtKB:P02461 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000205 ! collagen relationship: located_in CCO:C0000210 ! collagen type III relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001109 ! extracellular matrix relationship: transformation_of CCO:B0054859 ! CO3A1_HUMAN [Term] id: CCO:B0064444 name: CO4A3_HUMAN-Phosphoserine1435 def: "Protein CO4A3_HUMAN with the residue 1435 substituted with Phosphoserine" [UniProtKB:Q01955] comment: By similarity xref: UniProtKB:Q01955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055696 ! CO4A3_HUMAN [Term] id: CCO:B0064445 name: CO4A3_HUMAN-Phosphoserine1437 def: "Protein CO4A3_HUMAN with the residue 1437 substituted with Phosphoserine" [UniProtKB:Q01955] comment: By similarity xref: UniProtKB:Q01955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001771 ! metalloendopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000205 ! collagen relationship: located_in CCO:C0000211 ! collagen type IV relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055696 ! CO4A3_HUMAN [Term] id: CCO:B0064446 name: CO4A4_HUMAN-Phosphoserine139 def: "Protein CO4A4_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:P53420] xref: UniProtKB:P53420 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000205 ! collagen relationship: located_in CCO:C0000211 ! collagen type IV relationship: located_in CCO:C0000227 ! basement membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055509 ! CO4A4_HUMAN [Term] id: CCO:B0064447 name: COG3_HUMAN-N-acetylalanine2 def: "Protein COG3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q96JB2] xref: UniProtKB:Q96JB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058237 ! COG3_HUMAN [Term] id: CCO:B0064448 name: COG3_HUMAN-Phosphoserine533 def: "Protein COG3_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:Q96JB2] comment: By similarity xref: UniProtKB:Q96JB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000380 ! cis-Golgi network relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000842 ! Golgi transport complex relationship: transformation_of CCO:B0058237 ! COG3_HUMAN [Term] id: CCO:B0064449 name: CPEB1_HUMAN-Phosphothreonine172 def: "Protein CPEB1_HUMAN with the residue 172 substituted with Phosphothreonine" [UniProtKB:Q9BZB8] comment: by STK6 and CAMK2A; By similarity xref: UniProtKB:Q9BZB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0058593 ! CPEB1_HUMAN [Term] id: CCO:B0064450 name: CPLX3_HUMAN-Cysteine methyl ester155 def: "Protein CPLX3_HUMAN with the residue 155 substituted with Cysteine methyl ester" [UniProtKB:Q8WVH0] comment: By similarity xref: UniProtKB:Q8WVH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057992 ! CPLX3_HUMAN [Term] id: CCO:B0064451 name: CPLX4_HUMAN-Cysteine methyl ester157 def: "Protein CPLX4_HUMAN with the residue 157 substituted with Cysteine methyl ester" [UniProtKB:Q7Z7G2] comment: By similarity xref: UniProtKB:Q7Z7G2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0004214 ! syntaxin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0057214 ! CPLX4_HUMAN [Term] id: CCO:B0064452 name: CPT1A_HUMAN-N-acetylalanine2 def: "Protein CPT1A_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P50416] comment: By similarity xref: UniProtKB:P50416 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000568 ! carnitine O-palmitoyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: transformation_of CCO:B0055450 ! CPT1A_HUMAN [Term] id: CCO:B0064453 name: CPT1A_HUMAN-Phosphothreonine588 def: "Protein CPT1A_HUMAN with the residue 588 substituted with Phosphothreonine" [UniProtKB:P50416] comment: By similarity xref: UniProtKB:P50416 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055450 ! CPT1A_HUMAN [Term] id: CCO:B0064454 name: CPT1A_HUMAN-Phosphothreonine604 def: "Protein CPT1A_HUMAN with the residue 604 substituted with Phosphothreonine" [UniProtKB:P50416] comment: By similarity xref: UniProtKB:P50416 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055450 ! CPT1A_HUMAN [Term] id: CCO:B0064455 name: CPT1A_HUMAN-Phosphoserine741 def: "Protein CPT1A_HUMAN with the residue 741 substituted with Phosphoserine" [UniProtKB:P50416] comment: By similarity xref: UniProtKB:P50416 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055450 ! CPT1A_HUMAN [Term] id: CCO:B0064456 name: CPT1A_HUMAN-Phosphoserine747 def: "Protein CPT1A_HUMAN with the residue 747 substituted with Phosphoserine" [UniProtKB:P50416] comment: By similarity xref: UniProtKB:P50416 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055450 ! CPT1A_HUMAN [Term] id: CCO:B0064457 name: CPT2_HUMAN-N6-acetyllysine544 def: "Protein CPT2_HUMAN with the residue 544 substituted with N6-acetyllysine" [UniProtKB:P23786] comment: By similarity xref: UniProtKB:P23786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055167 ! CPT2_HUMAN [Term] id: CCO:B0064458 name: CR025_HUMAN-Phosphoserine326 def: "Protein CR025_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:Q96B23] xref: UniProtKB:Q96B23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005186 ! CR025_HUMAN [Term] id: CCO:B0064459 name: CR025_HUMAN-Phosphoserine329 def: "Protein CR025_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q96B23] xref: UniProtKB:Q96B23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005186 ! CR025_HUMAN [Term] id: CCO:B0064460 name: CR3L2_HUMAN-Phosphoserine191 def: "Protein CR3L2_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q70SY1] xref: UniProtKB:Q70SY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057093 ! CR3L2_HUMAN [Term] id: CCO:B0064461 name: CR3L3_HUMAN-Phosphoserine256 def: "Protein CR3L3_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q68CJ9] xref: UniProtKB:Q68CJ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056698 ! CR3L3_HUMAN [Term] id: CCO:B0064462 name: CR3L3_HUMAN-Phosphoserine260 def: "Protein CR3L3_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:Q68CJ9] xref: UniProtKB:Q68CJ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056698 ! CR3L3_HUMAN [Term] id: CCO:B0064463 name: CREM_HUMAN-Phosphoserine271 def: "Protein CREM_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q03060] xref: UniProtKB:Q03060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055719 ! CREM_HUMAN [Term] id: CCO:B0064464 name: CREM_HUMAN-Phosphoserine274 def: "Protein CREM_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q03060] xref: UniProtKB:Q03060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055719 ! CREM_HUMAN [Term] id: CCO:B0064465 name: CREM_HUMAN-Phosphoserine277 def: "Protein CREM_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q03060] xref: UniProtKB:Q03060 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001743 ! cAMP response element binding protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055719 ! CREM_HUMAN [Term] id: CCO:B0064466 name: CRF_HUMAN-Isoleucine amide194 def: "Protein CRF_HUMAN with the residue 194 substituted with Isoleucine amide" [UniProtKB:P06850] xref: UniProtKB:P06850 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0054906 ! CRF_HUMAN [Term] id: CCO:B0064467 name: CRIM1_HUMAN-Phosphothreonine1035 def: "Protein CRIM1_HUMAN with the residue 1035 substituted with Phosphothreonine" [UniProtKB:Q9NZV1] xref: UniProtKB:Q9NZV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001213 ! enzyme inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001347 ! insulin-like growth factor receptor activity relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059020 ! CRIM1_HUMAN [Term] id: CCO:B0064468 name: CRIP2_HUMAN-Phosphotyrosine77 def: "Protein CRIP2_HUMAN with the residue 77 substituted with Phosphotyrosine" [UniProtKB:P52943] xref: UniProtKB:P52943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048868 ! CRIP2_HUMAN [Term] id: CCO:B0064469 name: CRKL_HUMAN-Phosphoserine107 def: "Protein CRKL_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:P46109] comment: By similarity xref: UniProtKB:P46109 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055377 ! CRKL_HUMAN [Term] id: CCO:B0064470 name: CRKL_HUMAN-Phosphotyrosine132 def: "Protein CRKL_HUMAN with the residue 132 substituted with Phosphotyrosine" [UniProtKB:P46109] comment: By similarity xref: UniProtKB:P46109 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055377 ! CRKL_HUMAN [Term] id: CCO:B0064471 name: CRKL_HUMAN-Phosphotyrosine207 def: "Protein CRKL_HUMAN with the residue 207 substituted with Phosphotyrosine" [UniProtKB:P46109] xref: UniProtKB:P46109 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055377 ! CRKL_HUMAN [Term] id: CCO:B0064472 name: CRKL_HUMAN-Phosphotyrosine251 def: "Protein CRKL_HUMAN with the residue 251 substituted with Phosphotyrosine" [UniProtKB:P46109] xref: UniProtKB:P46109 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055377 ! CRKL_HUMAN [Term] id: CCO:B0064473 name: CRK_HUMAN-Phosphoserine41 def: "Protein CRK_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:P46108] comment: By similarity xref: UniProtKB:P46108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0006109 ! protein phosphorylated amino acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:B0064474 name: CRK_HUMAN-Phosphothreonine42 def: "Protein CRK_HUMAN with the residue 42 substituted with Phosphothreonine" [UniProtKB:P46108] comment: By similarity xref: UniProtKB:P46108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:B0064475 name: CRK_HUMAN-Phosphoserine74 def: "Protein CRK_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:P46108] xref: UniProtKB:P46108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:B0064476 name: CRK_HUMAN-Phosphoserine83 def: "Protein CRK_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P46108] xref: UniProtKB:P46108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:B0064477 name: CRK_HUMAN-Phosphotyrosine221 def: "Protein CRK_HUMAN with the residue 221 substituted with Phosphotyrosine" [UniProtKB:P46108] xref: UniProtKB:P46108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:B0064478 name: CRK_HUMAN-Phosphotyrosine239 def: "Protein CRK_HUMAN with the residue 239 substituted with Phosphotyrosine" [UniProtKB:P46108] xref: UniProtKB:P46108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:B0064479 name: CRTC1_HUMAN-Phosphoserine64 def: "Protein CRTC1_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q6UUV9] comment: By similarity xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064480 name: CRTC1_HUMAN-Phosphoserine86 def: "Protein CRTC1_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q6UUV9] comment: By similarity xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064481 name: CRTC1_HUMAN-Phosphoserine139 def: "Protein CRTC1_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q6UUV9] comment: By similarity xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001743 ! cAMP response element binding protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064482 name: CRTC1_HUMAN-Phosphothreonine149 def: "Protein CRTC1_HUMAN with the residue 149 substituted with Phosphothreonine" [UniProtKB:Q6UUV9] comment: By similarity xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064483 name: CRTC1_HUMAN-Phosphoserine151 def: "Protein CRTC1_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q6UUV9] comment: by SNF1lK2; xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064484 name: CRTC1_HUMAN-Phosphothreonine161 def: "Protein CRTC1_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:Q6UUV9] xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064485 name: CRTC1_HUMAN-Phosphoserine172 def: "Protein CRTC1_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q6UUV9] xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064486 name: CRTC1_HUMAN-Phosphoserine277 def: "Protein CRTC1_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q6UUV9] comment: By similarity xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064487 name: CRTC1_HUMAN-Phosphoserine440 def: "Protein CRTC1_HUMAN with the residue 440 substituted with Phosphoserine" [UniProtKB:Q6UUV9] comment: By similarity xref: UniProtKB:Q6UUV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056949 ! CRTC1_HUMAN [Term] id: CCO:B0064488 name: CRTC2_HUMAN-Phosphoserine64 def: "Protein CRTC2_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064489 name: CRTC2_HUMAN-Phosphoserine70 def: "Protein CRTC2_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064490 name: CRTC2_HUMAN-Phosphoserine86 def: "Protein CRTC2_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064491 name: CRTC2_HUMAN-Phosphoserine90 def: "Protein CRTC2_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064492 name: CRTC2_HUMAN-Phosphotyrosine130 def: "Protein CRTC2_HUMAN with the residue 130 substituted with Phosphotyrosine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064493 name: CRTC2_HUMAN-Phosphoserine136 def: "Protein CRTC2_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064494 name: CRTC2_HUMAN-Phosphothreonine169 def: "Protein CRTC2_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:Q53ET0] comment: By similarity xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064495 name: CRTC2_HUMAN-Phosphoserine171 def: "Protein CRTC2_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q53ET0] comment: by SNF1LK2; xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064496 name: CRTC2_HUMAN-Phosphothreonine177 def: "Protein CRTC2_HUMAN with the residue 177 substituted with Phosphothreonine" [UniProtKB:Q53ET0] comment: By similarity xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064497 name: CRTC2_HUMAN-Phosphoserine306 def: "Protein CRTC2_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064498 name: CRTC2_HUMAN-Phosphoserine368 def: "Protein CRTC2_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064499 name: CRTC2_HUMAN-Phosphoserine393 def: "Protein CRTC2_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064500 name: CRTC2_HUMAN-Phosphoserine433 def: "Protein CRTC2_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064501 name: CRTC2_HUMAN-Phosphoserine456 def: "Protein CRTC2_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064502 name: CRTC2_HUMAN-Phosphoserine489 def: "Protein CRTC2_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064503 name: CRTC2_HUMAN-Phosphoserine492 def: "Protein CRTC2_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064504 name: CRTC2_HUMAN-Phosphothreonine501 def: "Protein CRTC2_HUMAN with the residue 501 substituted with Phosphothreonine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064505 name: CRTC2_HUMAN-Phosphoserine613 def: "Protein CRTC2_HUMAN with the residue 613 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064506 name: CRTC2_HUMAN-Phosphoserine624 def: "Protein CRTC2_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:Q53ET0] xref: UniProtKB:Q53ET0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056349 ! CRTC2_HUMAN [Term] id: CCO:B0064507 name: CRTC3_HUMAN-Phosphoserine62 def: "Protein CRTC3_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q6UUV7] comment: By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064508 name: CRTC3_HUMAN-Phosphoserine129 def: "Protein CRTC3_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q6UUV7] comment: By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064509 name: CRTC3_HUMAN-Phosphothreonine160 def: "Protein CRTC3_HUMAN with the residue 160 substituted with Phosphothreonine" [UniProtKB:Q6UUV7] comment: By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064510 name: CRTC3_HUMAN-Phosphoserine162 def: "Protein CRTC3_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:Q6UUV7] comment: by SNF1LK2; By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064511 name: CRTC3_HUMAN-Phosphothreonine168 def: "Protein CRTC3_HUMAN with the residue 168 substituted with Phosphothreonine" [UniProtKB:Q6UUV7] comment: By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064512 name: CRTC3_HUMAN-Phosphoserine305 def: "Protein CRTC3_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q6UUV7] comment: By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064513 name: CRTC3_HUMAN-Phosphoserine370 def: "Protein CRTC3_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:Q6UUV7] xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064514 name: CRTC3_HUMAN-Phosphoserine391 def: "Protein CRTC3_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q6UUV7] xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064515 name: CRTC3_HUMAN-Phosphoserine396 def: "Protein CRTC3_HUMAN with the residue 396 substituted with Phosphoserine" [UniProtKB:Q6UUV7] xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064516 name: CRTC3_HUMAN-Phosphoserine410 def: "Protein CRTC3_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q6UUV7] comment: By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064517 name: CRTC3_HUMAN-Phosphoserine443 def: "Protein CRTC3_HUMAN with the residue 443 substituted with Phosphoserine" [UniProtKB:Q6UUV7] xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064518 name: CRTC3_HUMAN-Phosphoserine543 def: "Protein CRTC3_HUMAN with the residue 543 substituted with Phosphoserine" [UniProtKB:Q6UUV7] comment: By similarity xref: UniProtKB:Q6UUV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056948 ! CRTC3_HUMAN [Term] id: CCO:B0064519 name: CRY1_HUMAN-Phosphoserine247 def: "Protein CRY1_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:Q16526] comment: by MAPK; By similarity xref: UniProtKB:Q16526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056142 ! CRY1_HUMAN [Term] id: CCO:B0064520 name: CRY1_HUMAN-Phosphotyrosine432 def: "Protein CRY1_HUMAN with the residue 432 substituted with Phosphotyrosine" [UniProtKB:Q16526] xref: UniProtKB:Q16526 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056142 ! CRY1_HUMAN [Term] id: CCO:B0064521 name: CRY2_HUMAN-Phosphoserine266 def: "Protein CRY2_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q49AN0] comment: by MAPK; By similarity xref: UniProtKB:Q49AN0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056304 ! CRY2_HUMAN [Term] id: CCO:B0064522 name: CRY2_HUMAN-Phosphoserine558 def: "Protein CRY2_HUMAN with the residue 558 substituted with Phosphoserine" [UniProtKB:Q49AN0] comment: by MAPK; By similarity xref: UniProtKB:Q49AN0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056304 ! CRY2_HUMAN [Term] id: CCO:B0064523 name: CRYAA_HUMAN-N-acetylmethionine1 def: "Protein CRYAA_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064524 name: CRYAA_HUMAN-Phosphothreonine13 def: "Protein CRYAA_HUMAN with the residue 13 substituted with Phosphothreonine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064525 name: CRYAA_HUMAN-Omega-N-methylated arginine21 def: "Protein CRYAA_HUMAN with the residue 21 substituted with Omega-N-methylated arginine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064526 name: CRYAA_HUMAN-Phosphoserine45 def: "Protein CRYAA_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064527 name: CRYAA_HUMAN-N6-acetyllysine70 def: "Protein CRYAA_HUMAN with the residue 70 substituted with N6-acetyllysine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064528 name: CRYAA_HUMAN-N6-acetyllysine78 def: "Protein CRYAA_HUMAN with the residue 78 substituted with N6-acetyllysine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064529 name: CRYAA_HUMAN-N6-acetyllysine88 def: "Protein CRYAA_HUMAN with the residue 88 substituted with N6-acetyllysine" [UniProtKB:P02489] comment: alternate; xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064530 name: CRYAA_HUMAN-lysine88 def: "Protein CRYAA_HUMAN with the residue 88 substituted with lysine" [UniProtKB:P02489] comment: alternate; xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064531 name: CRYAA_HUMAN-asparagine101 def: "Protein CRYAA_HUMAN with the residue 101 substituted with asparagine" [UniProtKB:P02489] comment: partial; xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064532 name: CRYAA_HUMAN-Phosphoserine122 def: "Protein CRYAA_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001488 ! structural constituent of eye lens relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064533 name: CRYAA_HUMAN-Phosphothreonine140 def: "Protein CRYAA_HUMAN with the residue 140 substituted with Phosphothreonine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064534 name: CRYAA_HUMAN-N6-acetyllysine145 def: "Protein CRYAA_HUMAN with the residue 145 substituted with N6-acetyllysine" [UniProtKB:P02489] xref: UniProtKB:P02489 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054860 ! CRYAA_HUMAN [Term] id: CCO:B0064535 name: CRYAB_HUMAN-N-acetylmethionine1 def: "Protein CRYAB_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P02511] comment: Probable xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064536 name: CRYAB_HUMAN-Phosphoserine19 def: "Protein CRYAB_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064537 name: CRYAB_HUMAN-Phosphoserine21 def: "Protein CRYAB_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064538 name: CRYAB_HUMAN-Omega-N-methylated arginine22 def: "Protein CRYAB_HUMAN with the residue 22 substituted with Omega-N-methylated arginine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064539 name: CRYAB_HUMAN-Phosphoserine43 def: "Protein CRYAB_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064540 name: CRYAB_HUMAN-Phosphoserine45 def: "Protein CRYAB_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064541 name: CRYAB_HUMAN-Omega-N-methylated arginine50 def: "Protein CRYAB_HUMAN with the residue 50 substituted with Omega-N-methylated arginine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001488 ! structural constituent of eye lens relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064542 name: CRYAB_HUMAN-Phosphoserine53 def: "Protein CRYAB_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064543 name: CRYAB_HUMAN-Phosphoserine59 def: "Protein CRYAB_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064544 name: CRYAB_HUMAN-Phosphoserine76 def: "Protein CRYAB_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:P02511] xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064545 name: CRYAB_HUMAN-N6-acetyllysine92 def: "Protein CRYAB_HUMAN with the residue 92 substituted with N6-acetyllysine" [UniProtKB:P02511] comment: partial; xref: UniProtKB:P02511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:B0064546 name: CSDE1_HUMAN-Phosphothreonine444 def: "Protein CSDE1_HUMAN with the residue 444 substituted with Phosphothreonine" [UniProtKB:O75534] xref: UniProtKB:O75534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054648 ! CSDE1_HUMAN [Term] id: CCO:B0064547 name: CSDE1_HUMAN-Phosphoserine445 def: "Protein CSDE1_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:O75534] xref: UniProtKB:O75534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054648 ! CSDE1_HUMAN [Term] id: CCO:B0064548 name: CSDE1_HUMAN-Phosphoserine514 def: "Protein CSDE1_HUMAN with the residue 514 substituted with Phosphoserine" [UniProtKB:O75534] xref: UniProtKB:O75534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054648 ! CSDE1_HUMAN [Term] id: CCO:B0064549 name: CSEN_HUMAN-Phosphoserine63 def: "Protein CSEN_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:Q9Y2W7] comment: by CK1; xref: UniProtKB:Q9Y2W7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020218 ! CSEN_HUMAN [Term] id: CCO:B0064550 name: CSF1R_HUMAN-Phosphoserine555 def: "Protein CSF1R_HUMAN with the residue 555 substituted with Phosphoserine" [UniProtKB:P07333] xref: UniProtKB:P07333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054912 ! CSF1R_HUMAN [Term] id: CCO:B0064551 name: CSF1R_HUMAN-Phosphotyrosine556 def: "Protein CSF1R_HUMAN with the residue 556 substituted with Phosphotyrosine" [UniProtKB:P07333] xref: UniProtKB:P07333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054912 ! CSF1R_HUMAN [Term] id: CCO:B0064552 name: CSF1R_HUMAN-Phosphothreonine562 def: "Protein CSF1R_HUMAN with the residue 562 substituted with Phosphothreonine" [UniProtKB:P07333] xref: UniProtKB:P07333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001348 ! macrophage colony stimulating factor receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054912 ! CSF1R_HUMAN [Term] id: CCO:B0064553 name: CSF1R_HUMAN-Phosphothreonine567 def: "Protein CSF1R_HUMAN with the residue 567 substituted with Phosphothreonine" [UniProtKB:P07333] xref: UniProtKB:P07333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054912 ! CSF1R_HUMAN [Term] id: CCO:B0064554 name: CSF1R_HUMAN-Phosphotyrosine699 def: "Protein CSF1R_HUMAN with the residue 699 substituted with Phosphotyrosine" [UniProtKB:P07333] comment: by autocatalysis; By similarity xref: UniProtKB:P07333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054912 ! CSF1R_HUMAN [Term] id: CCO:B0064555 name: CSF1R_HUMAN-Phosphotyrosine708 def: "Protein CSF1R_HUMAN with the residue 708 substituted with Phosphotyrosine" [UniProtKB:P07333] comment: by autocatalysis; By similarity xref: UniProtKB:P07333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054912 ! CSF1R_HUMAN [Term] id: CCO:B0064556 name: CSF1R_HUMAN-Phosphotyrosine809 def: "Protein CSF1R_HUMAN with the residue 809 substituted with Phosphotyrosine" [UniProtKB:P07333] comment: by autocatalysis; By similarity xref: UniProtKB:P07333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054912 ! CSF1R_HUMAN [Term] id: CCO:B0064557 name: CSKI1_HUMAN-Phosphotyrosine253 def: "Protein CSKI1_HUMAN with the residue 253 substituted with Phosphotyrosine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064558 name: CSKI1_HUMAN-Phosphoserine646 def: "Protein CSKI1_HUMAN with the residue 646 substituted with Phosphoserine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064559 name: CSKI1_HUMAN-Phosphothreonine775 def: "Protein CSKI1_HUMAN with the residue 775 substituted with Phosphothreonine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064560 name: CSKI1_HUMAN-Phosphoserine787 def: "Protein CSKI1_HUMAN with the residue 787 substituted with Phosphoserine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064561 name: CSKI1_HUMAN-Phosphothreonine1065 def: "Protein CSKI1_HUMAN with the residue 1065 substituted with Phosphothreonine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064562 name: CSKI1_HUMAN-Phosphoserine1067 def: "Protein CSKI1_HUMAN with the residue 1067 substituted with Phosphoserine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064563 name: CSKI1_HUMAN-Phosphoserine1257 def: "Protein CSKI1_HUMAN with the residue 1257 substituted with Phosphoserine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064564 name: CSKI1_HUMAN-Phosphoserine1364 def: "Protein CSKI1_HUMAN with the residue 1364 substituted with Phosphoserine" [UniProtKB:Q8WXD9] comment: By similarity xref: UniProtKB:Q8WXD9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:B0064565 name: CSPG4_HUMAN-Phosphothreonine21 def: "Protein CSPG4_HUMAN with the residue 21 substituted with Phosphothreonine" [UniProtKB:Q6UVK1] xref: UniProtKB:Q6UVK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001387 ! receptor signaling protein tyrosine phosphatase signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001808 ! receptor signaling protein tyrosine kinase signaling protein activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0056950 ! CSPG4_HUMAN [Term] id: CCO:B0064566 name: CSPG4_HUMAN-Phosphothreonine2252 def: "Protein CSPG4_HUMAN with the residue 2252 substituted with Phosphothreonine" [UniProtKB:Q6UVK1] comment: by PKC/PRKCA; By similarity xref: UniProtKB:Q6UVK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056950 ! CSPG4_HUMAN [Term] id: CCO:B0064567 name: CTBP1_HUMAN-Phosphoserine300 def: "Protein CTBP1_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q13363] xref: UniProtKB:Q13363 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0007309 ! cofactor binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0021721 ! CTBP1_HUMAN [Term] id: CCO:B0064568 name: CTBP1_HUMAN-Phosphoserine422 def: "Protein CTBP1_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q13363] comment: by HIPK2; xref: UniProtKB:Q13363 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021721 ! CTBP1_HUMAN [Term] id: CCO:B0064569 name: CTBP2_HUMAN-Phosphoserine428 def: "Protein CTBP2_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:P56545] comment: By similarity xref: UniProtKB:P56545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0007309 ! cofactor binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0021723 ! CTBP2_HUMAN [Term] id: CCO:B0064570 name: CTCF_HUMAN-Phosphothreonine374 def: "Protein CTCF_HUMAN with the residue 374 substituted with Phosphothreonine" [UniProtKB:P49711] xref: UniProtKB:P49711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001630 ! CTCF_HUMAN [Term] id: CCO:B0064571 name: CTCF_HUMAN-Phosphoserine402 def: "Protein CTCF_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:P49711] xref: UniProtKB:P49711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001630 ! CTCF_HUMAN [Term] id: CCO:B0064572 name: CTF18_HUMAN-Phosphoserine225 def: "Protein CTF18_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q8WVB6] xref: UniProtKB:Q8WVB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043835 ! CTF18_HUMAN [Term] id: CCO:B0064573 name: CTF18_HUMAN-Phosphoserine865 def: "Protein CTF18_HUMAN with the residue 865 substituted with Phosphoserine" [UniProtKB:Q8WVB6] xref: UniProtKB:Q8WVB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043835 ! CTF18_HUMAN [Term] id: CCO:B0064574 name: CTNA1_HUMAN-Phosphotyrosine177 def: "Protein CTNA1_HUMAN with the residue 177 substituted with Phosphotyrosine" [UniProtKB:P35221] xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0064575 name: CTNA1_HUMAN-Phosphotyrosine619 def: "Protein CTNA1_HUMAN with the residue 619 substituted with Phosphotyrosine" [UniProtKB:P35221] xref: UniProtKB:P35221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:B0064576 name: CTND2_HUMAN-Phosphoserine32 def: "Protein CTND2_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064577 name: CTND2_HUMAN-Phosphoserine267 def: "Protein CTND2_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064578 name: CTND2_HUMAN-Phosphoserine276 def: "Protein CTND2_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064579 name: CTND2_HUMAN-Phosphoserine415 def: "Protein CTND2_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064580 name: CTND2_HUMAN-Phosphoserine474 def: "Protein CTND2_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:Q9UQB3] xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064581 name: CTND2_HUMAN-Phosphotyrosine516 def: "Protein CTND2_HUMAN with the residue 516 substituted with Phosphotyrosine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064582 name: CTND2_HUMAN-Phosphoserine534 def: "Protein CTND2_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064583 name: CTND2_HUMAN-Phosphoserine537 def: "Protein CTND2_HUMAN with the residue 537 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064584 name: CTND2_HUMAN-Phosphoserine1072 def: "Protein CTND2_HUMAN with the residue 1072 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064585 name: CTND2_HUMAN-Phosphoserine1076 def: "Protein CTND2_HUMAN with the residue 1076 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064586 name: CTND2_HUMAN-Phosphoserine1127 def: "Protein CTND2_HUMAN with the residue 1127 substituted with Phosphoserine" [UniProtKB:Q9UQB3] comment: By similarity xref: UniProtKB:Q9UQB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059277 ! CTND2_HUMAN [Term] id: CCO:B0064587 name: CTNL1_HUMAN-Phosphoserine538 def: "Protein CTNL1_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:Q9UBT7] xref: UniProtKB:Q9UBT7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0006104 ! cadherin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005881 ! CTNL1_HUMAN [Term] id: CCO:B0064588 name: CUL2_HUMAN-Phosphothreonine661 def: "Protein CUL2_HUMAN with the residue 661 substituted with Phosphothreonine" [UniProtKB:Q13617] xref: UniProtKB:Q13617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001760 ! CUL2_HUMAN [Term] id: CCO:B0064589 name: CUL4A_HUMAN-Phosphoserine10 def: "Protein CUL4A_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:Q13619] xref: UniProtKB:Q13619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: transformation_of CCO:B0001762 ! CUL4A_HUMAN [Term] id: CCO:B0064590 name: CUL4B_HUMAN-Phosphothreonine30 def: "Protein CUL4B_HUMAN with the residue 30 substituted with Phosphothreonine" [UniProtKB:Q13620] xref: UniProtKB:Q13620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001763 ! CUL4B_HUMAN [Term] id: CCO:B0064591 name: CUL4B_HUMAN-Phosphothreonine31 def: "Protein CUL4B_HUMAN with the residue 31 substituted with Phosphothreonine" [UniProtKB:Q13620] xref: UniProtKB:Q13620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001763 ! CUL4B_HUMAN [Term] id: CCO:B0064592 name: CUL4B_HUMAN-Phosphoserine35 def: "Protein CUL4B_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q13620] xref: UniProtKB:Q13620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001763 ! CUL4B_HUMAN [Term] id: CCO:B0064593 name: CUL4B_HUMAN-Phosphoserine128 def: "Protein CUL4B_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:Q13620] xref: UniProtKB:Q13620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001763 ! CUL4B_HUMAN [Term] id: CCO:B0064594 name: CUL4B_HUMAN-Phosphoserine175 def: "Protein CUL4B_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:Q13620] xref: UniProtKB:Q13620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001763 ! CUL4B_HUMAN [Term] id: CCO:B0064595 name: CUL5_HUMAN-Phosphothreonine210 def: "Protein CUL5_HUMAN with the residue 210 substituted with Phosphothreonine" [UniProtKB:Q93034] xref: UniProtKB:Q93034 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002027 ! CUL5_HUMAN [Term] id: CCO:B0064596 name: CUX1_HUMAN-Phosphoserine1496 def: "Protein CUX1_HUMAN with the residue 1496 substituted with Phosphoserine" [UniProtKB:P39880] xref: UniProtKB:P39880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:B0064597 name: CXCR2_HUMAN-Phosphoserine347 def: "Protein CXCR2_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:P25025] comment: Probable xref: UniProtKB:P25025 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055176 ! CXCR2_HUMAN [Term] id: CCO:B0064598 name: CXCR2_HUMAN-Phosphoserine351 def: "Protein CXCR2_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:P25025] comment: Probable xref: UniProtKB:P25025 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001264 ! interleukin-8 receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001673 ! mast cell granule relationship: transformation_of CCO:B0055176 ! CXCR2_HUMAN [Term] id: CCO:B0064599 name: CXCR2_HUMAN-Phosphoserine352 def: "Protein CXCR2_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:P25025] comment: Probable xref: UniProtKB:P25025 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055176 ! CXCR2_HUMAN [Term] id: CCO:B0064600 name: CXCR2_HUMAN-Phosphoserine353 def: "Protein CXCR2_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:P25025] comment: Probable xref: UniProtKB:P25025 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055176 ! CXCR2_HUMAN [Term] id: CCO:B0064601 name: CXCR4_HUMAN-Sulfotyrosine21 def: "Protein CXCR4_HUMAN with the residue 21 substituted with Sulfotyrosine" [UniProtKB:P61073] xref: UniProtKB:P61073 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:B0064602 name: CXCR4_HUMAN-Phosphoserine319 def: "Protein CXCR4_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:P61073] xref: UniProtKB:P61073 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001292 ! chemokine receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0003174 ! C-C chemokine receptor activity relationship: has_function CCO:F0003175 ! C-X-C chemokine receptor activity relationship: has_function CCO:F0004926 ! myosin light chain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001172 ! leading edge relationship: transformation_of CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:B0064603 name: CXCR4_HUMAN-Phosphoserine348 def: "Protein CXCR4_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:P61073] xref: UniProtKB:P61073 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:B0064604 name: CXCR4_HUMAN-Phosphoserine351 def: "Protein CXCR4_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:P61073] xref: UniProtKB:P61073 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:B0064605 name: CXXC1_HUMAN-Phosphoserine224 def: "Protein CXXC1_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:Q9P0U4] xref: UniProtKB:Q9P0U4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006110 ! unmethylated CpG binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0059034 ! CXXC1_HUMAN [Term] id: CCO:B0064606 name: CXXC1_HUMAN-Phosphothreonine227 def: "Protein CXXC1_HUMAN with the residue 227 substituted with Phosphothreonine" [UniProtKB:Q9P0U4] xref: UniProtKB:Q9P0U4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059034 ! CXXC1_HUMAN [Term] id: CCO:B0064607 name: CYC_HUMAN-N-acetylglycine2 def: "Protein CYC_HUMAN with the residue 2 substituted with N-acetylglycine" [UniProtKB:P99999] xref: UniProtKB:P99999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006087 ! electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000341 ! mitochondrial intermembrane space relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055677 ! CYC_HUMAN [Term] id: CCO:B0064608 name: CYFP1_HUMAN-Phosphotyrosine108 def: "Protein CYFP1_HUMAN with the residue 108 substituted with Phosphotyrosine" [UniProtKB:Q7L576] xref: UniProtKB:Q7L576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037573 ! CYFP1_HUMAN [Term] id: CCO:B0064609 name: CYFP1_HUMAN-Phosphothreonine1068 def: "Protein CYFP1_HUMAN with the residue 1068 substituted with Phosphothreonine" [UniProtKB:Q7L576] xref: UniProtKB:Q7L576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037573 ! CYFP1_HUMAN [Term] id: CCO:B0064610 name: CYH4_HUMAN-Phosphoserine356 def: "Protein CYH4_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:Q9UIA0] xref: UniProtKB:Q9UIA0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059155 ! CYH4_HUMAN [Term] id: CCO:B0064611 name: CYTSA_HUMAN-Phosphoserine832 def: "Protein CYTSA_HUMAN with the residue 832 substituted with Phosphoserine" [UniProtKB:Q69YQ0] xref: UniProtKB:Q69YQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001906 ! CYTSA_HUMAN [Term] id: CCO:B0064612 name: CYTSA_HUMAN-Phosphoserine868 def: "Protein CYTSA_HUMAN with the residue 868 substituted with Phosphoserine" [UniProtKB:Q69YQ0] xref: UniProtKB:Q69YQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001906 ! CYTSA_HUMAN [Term] id: CCO:B0064613 name: CYTSA_HUMAN-Phosphothreonine874 def: "Protein CYTSA_HUMAN with the residue 874 substituted with Phosphothreonine" [UniProtKB:Q69YQ0] xref: UniProtKB:Q69YQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001906 ! CYTSA_HUMAN [Term] id: CCO:B0064614 name: DAB2P_HUMAN-Phosphoserine992 def: "Protein DAB2P_HUMAN with the residue 992 substituted with Phosphoserine" [UniProtKB:Q5VWQ8] xref: UniProtKB:Q5VWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001899 ! DAB2P_HUMAN [Term] id: CCO:B0064615 name: DAB2P_HUMAN-Phosphoserine995 def: "Protein DAB2P_HUMAN with the residue 995 substituted with Phosphoserine" [UniProtKB:Q5VWQ8] xref: UniProtKB:Q5VWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001899 ! DAB2P_HUMAN [Term] id: CCO:B0064616 name: DAB2_HUMAN-Phosphothreonine151 def: "Protein DAB2_HUMAN with the residue 151 substituted with Phosphothreonine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064617 name: DAB2_HUMAN-Phosphotyrosine170 def: "Protein DAB2_HUMAN with the residue 170 substituted with Phosphotyrosine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064618 name: DAB2_HUMAN-Phosphothreonine221 def: "Protein DAB2_HUMAN with the residue 221 substituted with Phosphothreonine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064619 name: DAB2_HUMAN-Phosphoserine227 def: "Protein DAB2_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064620 name: DAB2_HUMAN-Phosphotyrosine342 def: "Protein DAB2_HUMAN with the residue 342 substituted with Phosphotyrosine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064621 name: DAB2_HUMAN-Phosphoserine393 def: "Protein DAB2_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064622 name: DAB2_HUMAN-Phosphoserine394 def: "Protein DAB2_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064623 name: DAB2_HUMAN-Phosphoserine401 def: "Protein DAB2_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:P98082] xref: UniProtKB:P98082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0055668 ! DAB2_HUMAN [Term] id: CCO:B0064624 name: DAD1_HUMAN-N-acetylserine2 def: "Protein DAD1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P61803] xref: UniProtKB:P61803 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000962 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000535 ! oligosaccharyl transferase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055612 ! DAD1_HUMAN [Term] id: CCO:B0064625 name: DAP1_HUMAN-N-acetylserine2 def: "Protein DAP1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P51397] xref: UniProtKB:P51397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055463 ! DAP1_HUMAN [Term] id: CCO:B0064626 name: DAP1_HUMAN-Phosphoserine3 def: "Protein DAP1_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:P51397] xref: UniProtKB:P51397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055463 ! DAP1_HUMAN [Term] id: CCO:B0064627 name: DAP1_HUMAN-Phosphoserine49 def: "Protein DAP1_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:P51397] xref: UniProtKB:P51397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055463 ! DAP1_HUMAN [Term] id: CCO:B0064628 name: DAP1_HUMAN-Phosphoserine51 def: "Protein DAP1_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P51397] xref: UniProtKB:P51397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055463 ! DAP1_HUMAN [Term] id: CCO:B0064629 name: DAP1_HUMAN-Phosphoserine91 def: "Protein DAP1_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:P51397] xref: UniProtKB:P51397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055463 ! DAP1_HUMAN [Term] id: CCO:B0064630 name: DAPLE_HUMAN-Phosphoserine1806 def: "Protein DAPLE_HUMAN with the residue 1806 substituted with Phosphoserine" [UniProtKB:Q9P219] xref: UniProtKB:Q9P219 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059050 ! DAPLE_HUMAN [Term] id: CCO:B0064631 name: DAPP1_HUMAN-Phosphotyrosine139 def: "Protein DAPP1_HUMAN with the residue 139 substituted with Phosphotyrosine" [UniProtKB:Q9UN19] xref: UniProtKB:Q9UN19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059245 ! DAPP1_HUMAN [Term] id: CCO:B0064632 name: DAPP1_HUMAN-Phosphoserine141 def: "Protein DAPP1_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q9UN19] comment: By similarity xref: UniProtKB:Q9UN19 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0005556 ! phosphoinositide 3-kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059245 ! DAPP1_HUMAN [Term] id: CCO:B0064633 name: DBF4A_HUMAN-Phosphoserine354 def: "Protein DBF4A_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q9UBU7] xref: UniProtKB:Q9UBU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002194 ! DBF4A_HUMAN [Term] id: CCO:B0064634 name: DBF4A_HUMAN-Phosphoserine359 def: "Protein DBF4A_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:Q9UBU7] xref: UniProtKB:Q9UBU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002194 ! DBF4A_HUMAN [Term] id: CCO:B0064635 name: DBNL_HUMAN-Phosphotyrosine162 def: "Protein DBNL_HUMAN with the residue 162 substituted with Phosphotyrosine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064636 name: DBNL_HUMAN-Phosphoserine178 def: "Protein DBNL_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064637 name: DBNL_HUMAN-Phosphoserine232 def: "Protein DBNL_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064638 name: DBNL_HUMAN-Phosphoserine269 def: "Protein DBNL_HUMAN with the residue 269 substituted with Phosphoserine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064639 name: DBNL_HUMAN-Phosphothreonine270 def: "Protein DBNL_HUMAN with the residue 270 substituted with Phosphothreonine" [UniProtKB:Q9UJU6] comment: By similarity xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064640 name: DBNL_HUMAN-Phosphoserine272 def: "Protein DBNL_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064641 name: DBNL_HUMAN-Phosphoserine275 def: "Protein DBNL_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064642 name: DBNL_HUMAN-Phosphoserine283 def: "Protein DBNL_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064643 name: DBNL_HUMAN-Phosphothreonine291 def: "Protein DBNL_HUMAN with the residue 291 substituted with Phosphothreonine" [UniProtKB:Q9UJU6] xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064644 name: DBNL_HUMAN-Phosphotyrosine334 def: "Protein DBNL_HUMAN with the residue 334 substituted with Phosphotyrosine" [UniProtKB:Q9UJU6] comment: By similarity xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064645 name: DBNL_HUMAN-Phosphotyrosine344 def: "Protein DBNL_HUMAN with the residue 344 substituted with Phosphotyrosine" [UniProtKB:Q9UJU6] comment: By similarity xref: UniProtKB:Q9UJU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:B0064646 name: DCBD2_HUMAN-Phosphoserine606 def: "Protein DCBD2_HUMAN with the residue 606 substituted with Phosphoserine" [UniProtKB:Q96PD2] xref: UniProtKB:Q96PD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058328 ! DCBD2_HUMAN [Term] id: CCO:B0064647 name: DCBD2_HUMAN-Phosphotyrosine750 def: "Protein DCBD2_HUMAN with the residue 750 substituted with Phosphotyrosine" [UniProtKB:Q96PD2] xref: UniProtKB:Q96PD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058328 ! DCBD2_HUMAN [Term] id: CCO:B0064648 name: DCLK1_HUMAN-Phosphoserine305 def: "Protein DCLK1_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064649 name: DCLK1_HUMAN-Phosphoserine307 def: "Protein DCLK1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064650 name: DCLK1_HUMAN-Phosphoserine332 def: "Protein DCLK1_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064651 name: DCLK1_HUMAN-Phosphothreonine336 def: "Protein DCLK1_HUMAN with the residue 336 substituted with Phosphothreonine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064652 name: DCLK1_HUMAN-Phosphoserine364 def: "Protein DCLK1_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064653 name: DCLK1_HUMAN-Phosphoserine376 def: "Protein DCLK1_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064654 name: DCLK1_HUMAN-Phosphotyrosine493 def: "Protein DCLK1_HUMAN with the residue 493 substituted with Phosphotyrosine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064655 name: DCLK1_HUMAN-Phosphotyrosine520 def: "Protein DCLK1_HUMAN with the residue 520 substituted with Phosphotyrosine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064656 name: DCLK1_HUMAN-Phosphoserine722 def: "Protein DCLK1_HUMAN with the residue 722 substituted with Phosphoserine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064657 name: DCLK1_HUMAN-Phosphoserine726 def: "Protein DCLK1_HUMAN with the residue 726 substituted with Phosphoserine" [UniProtKB:O15075] comment: By similarity xref: UniProtKB:O15075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030613 ! DCLK1_HUMAN [Term] id: CCO:B0064658 name: DCMC_HUMAN-Phosphoserine387 def: "Protein DCMC_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:O95822] xref: UniProtKB:O95822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054797 ! DCMC_HUMAN [Term] id: CCO:B0064659 name: DCOR_HUMAN-Phosphoserine303 def: "Protein DCOR_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:P11926] comment: by CK2; By similarity xref: UniProtKB:P11926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054997 ! DCOR_HUMAN [Term] id: CCO:B0064660 name: DCOR_HUMAN-S-nitrosocysteine360 def: "Protein DCOR_HUMAN with the residue 360 substituted with S-nitrosocysteine" [UniProtKB:P11926] comment: in inhibited form; Probable xref: UniProtKB:P11926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054997 ! DCOR_HUMAN [Term] id: CCO:B0064661 name: DCP1A_HUMAN-Phosphoserine142 def: "Protein DCP1A_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0064662 name: DCP1A_HUMAN-Phosphothreonine401 def: "Protein DCP1A_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0064663 name: DCP1A_HUMAN-Phosphoserine522 def: "Protein DCP1A_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q9NPI6] xref: UniProtKB:Q9NPI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:B0064664 name: DCX_HUMAN-Phosphothreonine95 def: "Protein DCX_HUMAN with the residue 95 substituted with Phosphothreonine" [UniProtKB:O43602] comment: by PKC; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064665 name: DCX_HUMAN-Phosphotyrosine151 def: "Protein DCX_HUMAN with the residue 151 substituted with Phosphotyrosine" [UniProtKB:O43602] comment: by ABL; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064666 name: DCX_HUMAN-Phosphoserine155 def: "Protein DCX_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:O43602] comment: by PKC; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064667 name: DCX_HUMAN-Phosphoserine171 def: "Protein DCX_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:O43602] comment: by CK2; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064668 name: DCX_HUMAN-Phosphoserine191 def: "Protein DCX_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:O43602] comment: by PKC; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064669 name: DCX_HUMAN-Phosphoserine196 def: "Protein DCX_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:O43602] comment: by CK2; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064670 name: DCX_HUMAN-Phosphoserine346 def: "Protein DCX_HUMAN with the residue 346 substituted with Phosphoserine" [UniProtKB:O43602] comment: by CK2; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064671 name: DCX_HUMAN-Phosphoserine375 def: "Protein DCX_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:O43602] comment: by PKC; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064672 name: DCX_HUMAN-Phosphoserine385 def: "Protein DCX_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:O43602] comment: By similarity xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064673 name: DCX_HUMAN-Phosphoserine387 def: "Protein DCX_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:O43602] comment: by CK2; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064674 name: DCX_HUMAN-Phosphoserine398 def: "Protein DCX_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:O43602] comment: By similarity xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064675 name: DCX_HUMAN-Phosphothreonine402 def: "Protein DCX_HUMAN with the residue 402 substituted with Phosphothreonine" [UniProtKB:O43602] comment: by PKC and MAPK; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064676 name: DCX_HUMAN-Phosphoserine408 def: "Protein DCX_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:O43602] comment: by MAPK; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064677 name: DCX_HUMAN-Phosphoserine411 def: "Protein DCX_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:O43602] xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064678 name: DCX_HUMAN-Phosphothreonine412 def: "Protein DCX_HUMAN with the residue 412 substituted with Phosphothreonine" [UniProtKB:O43602] comment: by MAPK; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064679 name: DCX_HUMAN-Phosphoserine415 def: "Protein DCX_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:O43602] comment: by MAPK; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064680 name: DCX_HUMAN-Phosphoserine418 def: "Protein DCX_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:O43602] comment: by PKC; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064681 name: DCX_HUMAN-Phosphoserine430 def: "Protein DCX_HUMAN with the residue 430 substituted with Phosphoserine" [UniProtKB:O43602] comment: by CK2; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064682 name: DCX_HUMAN-Phosphoserine436 def: "Protein DCX_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:O43602] comment: by CK2; Potential xref: UniProtKB:O43602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030615 ! DCX_HUMAN [Term] id: CCO:B0064683 name: DD19B_HUMAN-Phosphoserine86 def: "Protein DD19B_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q9UMR2] xref: UniProtKB:Q9UMR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0043447 ! DD19B_HUMAN [Term] id: CCO:B0064684 name: DDAH1_HUMAN-N-acetylalanine2 def: "Protein DDAH1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O94760] xref: UniProtKB:O94760 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003126 ! dimethylargininase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054696 ! DDAH1_HUMAN [Term] id: CCO:B0064685 name: DDEF1_HUMAN-Phosphoserine839 def: "Protein DDEF1_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:Q9ULH1] xref: UniProtKB:Q9ULH1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059225 ! DDEF1_HUMAN [Term] id: CCO:B0064686 name: DDEF1_HUMAN-Phosphoserine843 def: "Protein DDEF1_HUMAN with the residue 843 substituted with Phosphoserine" [UniProtKB:Q9ULH1] xref: UniProtKB:Q9ULH1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059225 ! DDEF1_HUMAN [Term] id: CCO:B0064687 name: DDEF1_HUMAN-Phosphoserine1008 def: "Protein DDEF1_HUMAN with the residue 1008 substituted with Phosphoserine" [UniProtKB:Q9ULH1] xref: UniProtKB:Q9ULH1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059225 ! DDEF1_HUMAN [Term] id: CCO:B0064688 name: DDEF1_HUMAN-Phosphoserine1027 def: "Protein DDEF1_HUMAN with the residue 1027 substituted with Phosphoserine" [UniProtKB:Q9ULH1] xref: UniProtKB:Q9ULH1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059225 ! DDEF1_HUMAN [Term] id: CCO:B0064689 name: DDEF2_HUMAN-Phosphoserine701 def: "Protein DDEF2_HUMAN with the residue 701 substituted with Phosphoserine" [UniProtKB:O43150] xref: UniProtKB:O43150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054450 ! DDEF2_HUMAN [Term] id: CCO:B0064690 name: DDR2_HUMAN-Phosphotyrosine736 def: "Protein DDR2_HUMAN with the residue 736 substituted with Phosphotyrosine" [UniProtKB:Q16832] xref: UniProtKB:Q16832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056178 ! DDR2_HUMAN [Term] id: CCO:B0064691 name: DDR2_HUMAN-Phosphotyrosine740 def: "Protein DDR2_HUMAN with the residue 740 substituted with Phosphotyrosine" [UniProtKB:Q16832] comment: by autocatalysis; By similarity xref: UniProtKB:Q16832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056178 ! DDR2_HUMAN [Term] id: CCO:B0064692 name: DDX1_HUMAN-Phosphothreonine80 def: "Protein DDX1_HUMAN with the residue 80 substituted with Phosphothreonine" [UniProtKB:Q92499] xref: UniProtKB:Q92499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058058 ! DDX1_HUMAN [Term] id: CCO:B0064693 name: DDX1_HUMAN-Phosphothreonine83 def: "Protein DDX1_HUMAN with the residue 83 substituted with Phosphothreonine" [UniProtKB:Q92499] xref: UniProtKB:Q92499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058058 ! DDX1_HUMAN [Term] id: CCO:B0064694 name: DDX1_HUMAN-Phosphotyrosine628 def: "Protein DDX1_HUMAN with the residue 628 substituted with Phosphotyrosine" [UniProtKB:Q92499] xref: UniProtKB:Q92499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0058058 ! DDX1_HUMAN [Term] id: CCO:B0064695 name: DDX20_HUMAN-Phosphoserine48 def: "Protein DDX20_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064696 name: DDX20_HUMAN-Phosphoserine500 def: "Protein DDX20_HUMAN with the residue 500 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064697 name: DDX20_HUMAN-Phosphoserine532 def: "Protein DDX20_HUMAN with the residue 532 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064698 name: DDX20_HUMAN-Phosphothreonine552 def: "Protein DDX20_HUMAN with the residue 552 substituted with Phosphothreonine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064699 name: DDX20_HUMAN-Phosphoserine649 def: "Protein DDX20_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064700 name: DDX20_HUMAN-Phosphoserine652 def: "Protein DDX20_HUMAN with the residue 652 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064701 name: DDX20_HUMAN-Phosphoserine654 def: "Protein DDX20_HUMAN with the residue 654 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064702 name: DDX20_HUMAN-Phosphoserine656 def: "Protein DDX20_HUMAN with the residue 656 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064703 name: DDX20_HUMAN-Phosphoserine672 def: "Protein DDX20_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064704 name: DDX20_HUMAN-Phosphoserine677 def: "Protein DDX20_HUMAN with the residue 677 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064705 name: DDX20_HUMAN-Phosphoserine678 def: "Protein DDX20_HUMAN with the residue 678 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064706 name: DDX20_HUMAN-Phosphoserine703 def: "Protein DDX20_HUMAN with the residue 703 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064707 name: DDX20_HUMAN-Phosphothreonine705 def: "Protein DDX20_HUMAN with the residue 705 substituted with Phosphothreonine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064708 name: DDX20_HUMAN-Phosphoserine714 def: "Protein DDX20_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:Q9UHI6] xref: UniProtKB:Q9UHI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:B0064709 name: DDX24_HUMAN-Phosphoserine94 def: "Protein DDX24_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q9GZR7] xref: UniProtKB:Q9GZR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:B0064710 name: DDX24_HUMAN-Phosphoserine287 def: "Protein DDX24_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q9GZR7] xref: UniProtKB:Q9GZR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:B0064711 name: DDX24_HUMAN-Phosphoserine295 def: "Protein DDX24_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q9GZR7] xref: UniProtKB:Q9GZR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000309 ! RNA helicase activity relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:B0064712 name: DDX54_HUMAN-Phosphoserine34 def: "Protein DDX54_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:Q8TDD1] xref: UniProtKB:Q8TDD1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057925 ! DDX54_HUMAN [Term] id: CCO:B0064713 name: DDX54_HUMAN-Phosphoserine39 def: "Protein DDX54_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q8TDD1] xref: UniProtKB:Q8TDD1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057925 ! DDX54_HUMAN [Term] id: CCO:B0064714 name: DDX54_HUMAN-Phosphoserine41 def: "Protein DDX54_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q8TDD1] xref: UniProtKB:Q8TDD1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057925 ! DDX54_HUMAN [Term] id: CCO:B0064715 name: DDX54_HUMAN-Phosphoserine75 def: "Protein DDX54_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q8TDD1] xref: UniProtKB:Q8TDD1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057925 ! DDX54_HUMAN [Term] id: CCO:B0064716 name: DDX54_HUMAN-Phosphoserine644 def: "Protein DDX54_HUMAN with the residue 644 substituted with Phosphoserine" [UniProtKB:Q8TDD1] xref: UniProtKB:Q8TDD1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057925 ! DDX54_HUMAN [Term] id: CCO:B0064717 name: DDX54_HUMAN-Phosphoserine782 def: "Protein DDX54_HUMAN with the residue 782 substituted with Phosphoserine" [UniProtKB:Q8TDD1] xref: UniProtKB:Q8TDD1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057925 ! DDX54_HUMAN [Term] id: CCO:B0064718 name: DDX54_HUMAN-Phosphoserine788 def: "Protein DDX54_HUMAN with the residue 788 substituted with Phosphoserine" [UniProtKB:Q8TDD1] xref: UniProtKB:Q8TDD1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057925 ! DDX54_HUMAN [Term] id: CCO:B0064719 name: DDX5_HUMAN-Phosphotyrosine202 def: "Protein DDX5_HUMAN with the residue 202 substituted with Phosphotyrosine" [UniProtKB:P17844] xref: UniProtKB:P17844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005729 ! DDX5_HUMAN [Term] id: CCO:B0064720 name: DEAF1_HUMAN-Phosphoserine176 def: "Protein DEAF1_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:O75398] xref: UniProtKB:O75398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054631 ! DEAF1_HUMAN [Term] id: CCO:B0064721 name: DEF1_HUMAN-Phosphotyrosine85 def: "Protein DEF1_HUMAN with the residue 85 substituted with Phosphotyrosine" [UniProtKB:P59665] xref: UniProtKB:P59665 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006339 ! DEF1_HUMAN [Term] id: CCO:B0064722 name: DEMA_HUMAN-Phosphothreonine10 def: "Protein DEMA_HUMAN with the residue 10 substituted with Phosphothreonine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064723 name: DEMA_HUMAN-Phosphoserine14 def: "Protein DEMA_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064724 name: DEMA_HUMAN-Phosphoserine16 def: "Protein DEMA_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064725 name: DEMA_HUMAN-Phosphoserine22 def: "Protein DEMA_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064726 name: DEMA_HUMAN-Phosphoserine26 def: "Protein DEMA_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064727 name: DEMA_HUMAN-Phosphoserine28 def: "Protein DEMA_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064728 name: DEMA_HUMAN-Phosphoserine87 def: "Protein DEMA_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q08495] comment: By similarity xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064729 name: DEMA_HUMAN-Phosphothreonine91 def: "Protein DEMA_HUMAN with the residue 91 substituted with Phosphothreonine" [UniProtKB:Q08495] comment: By similarity xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064730 name: DEMA_HUMAN-Phosphoserine92 def: "Protein DEMA_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064731 name: DEMA_HUMAN-Phosphoserine96 def: "Protein DEMA_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064732 name: DEMA_HUMAN-Phosphoserine105 def: "Protein DEMA_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064733 name: DEMA_HUMAN-Phosphoserine156 def: "Protein DEMA_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064734 name: DEMA_HUMAN-Phosphoserine226 def: "Protein DEMA_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064735 name: DEMA_HUMAN-Phosphoserine289 def: "Protein DEMA_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064736 name: DEMA_HUMAN-Phosphoserine333 def: "Protein DEMA_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064737 name: DEMA_HUMAN-Phosphoserine372 def: "Protein DEMA_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q08495] xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064738 name: DEMA_HUMAN-Phosphoserine403 def: "Protein DEMA_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:Q08495] comment: by PKA; xref: UniProtKB:Q08495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:B0064739 name: DEP1A_HUMAN-Phosphoserine512 def: "Protein DEP1A_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q5TB30] xref: UniProtKB:Q5TB30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056604 ! DEP1A_HUMAN [Term] id: CCO:B0064740 name: DEPD7_HUMAN-Phosphoserine152 def: "Protein DEPD7_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q96QD5] xref: UniProtKB:Q96QD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0058352 ! DEPD7_HUMAN [Term] id: CCO:B0064741 name: DERL1_HUMAN-Phosphothreonine202 def: "Protein DERL1_HUMAN with the residue 202 substituted with Phosphothreonine" [UniProtKB:Q9BUN8] xref: UniProtKB:Q9BUN8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005648 ! MHC class I protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: transformation_of CCO:B0058523 ! DERL1_HUMAN [Term] id: CCO:B0064742 name: DFFA_HUMAN-Phosphoserine257 def: "Protein DFFA_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:O00273] xref: UniProtKB:O00273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054307 ! DFFA_HUMAN [Term] id: CCO:B0064743 name: DFFA_HUMAN-Phosphoserine310 def: "Protein DFFA_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:O00273] xref: UniProtKB:O00273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054307 ! DFFA_HUMAN [Term] id: CCO:B0064744 name: DFFA_HUMAN-Phosphoserine315 def: "Protein DFFA_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:O00273] xref: UniProtKB:O00273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000933 ! caspase-activated deoxyribonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0054307 ! DFFA_HUMAN [Term] id: CCO:B0064745 name: DGCR8_HUMAN-Phosphoserine92 def: "Protein DGCR8_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q8WYQ5] xref: UniProtKB:Q8WYQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:B0064746 name: DGCR8_HUMAN-Phosphoserine95 def: "Protein DGCR8_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q8WYQ5] xref: UniProtKB:Q8WYQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:B0064747 name: DGCR8_HUMAN-Phosphoserine109 def: "Protein DGCR8_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q8WYQ5] xref: UniProtKB:Q8WYQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:B0064748 name: DGCR8_HUMAN-Phosphoserine271 def: "Protein DGCR8_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q8WYQ5] xref: UniProtKB:Q8WYQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:B0064749 name: DGCR8_HUMAN-Phosphoserine275 def: "Protein DGCR8_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q8WYQ5] xref: UniProtKB:Q8WYQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:B0064750 name: DGCR8_HUMAN-Phosphoserine377 def: "Protein DGCR8_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q8WYQ5] xref: UniProtKB:Q8WYQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:B0064751 name: DGKA_HUMAN-Phosphotyrosine22 def: "Protein DGKA_HUMAN with the residue 22 substituted with Phosphotyrosine" [UniProtKB:P23743] xref: UniProtKB:P23743 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0055162 ! DGKA_HUMAN [Term] id: CCO:B0064752 name: DGKI_HUMAN-Phosphoserine1049 def: "Protein DGKI_HUMAN with the residue 1049 substituted with Phosphoserine" [UniProtKB:O75912] xref: UniProtKB:O75912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054677 ! DGKI_HUMAN [Term] id: CCO:B0064753 name: DGKI_HUMAN-Phosphotyrosine1053 def: "Protein DGKI_HUMAN with the residue 1053 substituted with Phosphotyrosine" [UniProtKB:O75912] xref: UniProtKB:O75912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054677 ! DGKI_HUMAN [Term] id: CCO:B0064754 name: DGKK_HUMAN-Phosphotyrosine78 def: "Protein DGKK_HUMAN with the residue 78 substituted with Phosphotyrosine" [UniProtKB:Q5KSL6] xref: UniProtKB:Q5KSL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056515 ! DGKK_HUMAN [Term] id: CCO:B0064755 name: DGKZ_HUMAN-Phosphoserine686 def: "Protein DGKZ_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:Q13574] xref: UniProtKB:Q13574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055932 ! DGKZ_HUMAN [Term] id: CCO:B0064756 name: DHE3_HUMAN-N6-acetyllysine84 def: "Protein DHE3_HUMAN with the residue 84 substituted with N6-acetyllysine" [UniProtKB:P00367] comment: By similarity xref: UniProtKB:P00367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000771 ! glutamate dehydrogenase activity relationship: has_function CCO:F0000772 ! glutamate dehydrogenase [NAD(P)+] activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:B0064757 name: DHE3_HUMAN-Phosphotyrosine135 def: "Protein DHE3_HUMAN with the residue 135 substituted with Phosphotyrosine" [UniProtKB:P00367] comment: By similarity xref: UniProtKB:P00367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:B0064758 name: DHE3_HUMAN-Phosphoserine227 def: "Protein DHE3_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P00367] comment: By similarity xref: UniProtKB:P00367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:B0064759 name: DHE3_HUMAN-N6-acetyllysine503 def: "Protein DHE3_HUMAN with the residue 503 substituted with N6-acetyllysine" [UniProtKB:P00367] comment: By similarity xref: UniProtKB:P00367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:B0064760 name: DHE3_HUMAN-Phosphotyrosine512 def: "Protein DHE3_HUMAN with the residue 512 substituted with Phosphotyrosine" [UniProtKB:P00367] comment: By similarity xref: UniProtKB:P00367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:B0064761 name: DHE3_HUMAN-N6-acetyllysine527 def: "Protein DHE3_HUMAN with the residue 527 substituted with N6-acetyllysine" [UniProtKB:P00367] comment: By similarity xref: UniProtKB:P00367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:B0064762 name: DHYS_HUMAN-Phosphoserine78 def: "Protein DHYS_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:P49366] xref: UniProtKB:P49366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055423 ! DHYS_HUMAN [Term] id: CCO:B0064763 name: DHYS_HUMAN-Phosphothreonine88 def: "Protein DHYS_HUMAN with the residue 88 substituted with Phosphothreonine" [UniProtKB:P49366] xref: UniProtKB:P49366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055423 ! DHYS_HUMAN [Term] id: CCO:B0064764 name: DIAP2_HUMAN-Phosphotyrosine632 def: "Protein DIAP2_HUMAN with the residue 632 substituted with Phosphotyrosine" [UniProtKB:O60879] xref: UniProtKB:O60879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054584 ! DIAP2_HUMAN [Term] id: CCO:B0064765 name: DIXC1_HUMAN-Phosphotyrosine642 def: "Protein DIXC1_HUMAN with the residue 642 substituted with Phosphotyrosine" [UniProtKB:Q155Q3] xref: UniProtKB:Q155Q3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056077 ! DIXC1_HUMAN [Term] id: CCO:B0064766 name: DLG1_HUMAN-Phosphothreonine115 def: "Protein DLG1_HUMAN with the residue 115 substituted with Phosphothreonine" [UniProtKB:Q12959] xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0064767 name: DLG1_HUMAN-Phosphoserine122 def: "Protein DLG1_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q12959] xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0064768 name: DLG1_HUMAN-Phosphoserine575 def: "Protein DLG1_HUMAN with the residue 575 substituted with Phosphoserine" [UniProtKB:Q12959] xref: UniProtKB:Q12959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:B0064769 name: DLG3_HUMAN-Phosphotyrosine808 def: "Protein DLG3_HUMAN with the residue 808 substituted with Phosphotyrosine" [UniProtKB:Q92796] xref: UniProtKB:Q92796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023306 ! DLG3_HUMAN [Term] id: CCO:B0064770 name: DLGP4_HUMAN-Phosphoserine368 def: "Protein DLGP4_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q9Y2H0] comment: By similarity xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064771 name: DLGP4_HUMAN-Phosphotyrosine369 def: "Protein DLGP4_HUMAN with the residue 369 substituted with Phosphotyrosine" [UniProtKB:Q9Y2H0] xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064772 name: DLGP4_HUMAN-Phosphoserine378 def: "Protein DLGP4_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:Q9Y2H0] comment: By similarity xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064773 name: DLGP4_HUMAN-Phosphoserine397 def: "Protein DLGP4_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q9Y2H0] comment: By similarity xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064774 name: DLGP4_HUMAN-Phosphoserine421 def: "Protein DLGP4_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q9Y2H0] comment: By similarity xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064775 name: DLGP4_HUMAN-Phosphoserine512 def: "Protein DLGP4_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q9Y2H0] comment: By similarity xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064776 name: DLGP4_HUMAN-Phosphothreonine915 def: "Protein DLGP4_HUMAN with the residue 915 substituted with Phosphothreonine" [UniProtKB:Q9Y2H0] xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064777 name: DLGP4_HUMAN-Phosphoserine973 def: "Protein DLGP4_HUMAN with the residue 973 substituted with Phosphoserine" [UniProtKB:Q9Y2H0] comment: By similarity xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064778 name: DLGP4_HUMAN-Phosphotyrosine984 def: "Protein DLGP4_HUMAN with the residue 984 substituted with Phosphotyrosine" [UniProtKB:Q9Y2H0] xref: UniProtKB:Q9Y2H0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:B0064779 name: DLGP5_HUMAN-Phosphothreonine326 def: "Protein DLGP5_HUMAN with the residue 326 substituted with Phosphothreonine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0064780 name: DLGP5_HUMAN-Phosphothreonine338 def: "Protein DLGP5_HUMAN with the residue 338 substituted with Phosphothreonine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0064781 name: DLGP5_HUMAN-Phosphothreonine344 def: "Protein DLGP5_HUMAN with the residue 344 substituted with Phosphothreonine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0064782 name: DLGP5_HUMAN-Phosphoserine725 def: "Protein DLGP5_HUMAN with the residue 725 substituted with Phosphoserine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0064783 name: DLGP5_HUMAN-Phosphothreonine784 def: "Protein DLGP5_HUMAN with the residue 784 substituted with Phosphothreonine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0064784 name: DLGP5_HUMAN-Phosphothreonine799 def: "Protein DLGP5_HUMAN with the residue 799 substituted with Phosphothreonine" [UniProtKB:Q15398] xref: UniProtKB:Q15398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001807 ! DLGP5_HUMAN [Term] id: CCO:B0064785 name: DLX2_HUMAN-Phosphoserine227 def: "Protein DLX2_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q07687] xref: UniProtKB:Q07687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037982 ! DLX2_HUMAN [Term] id: CCO:B0064786 name: DLX2_HUMAN-Phosphoserine232 def: "Protein DLX2_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q07687] xref: UniProtKB:Q07687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0037982 ! DLX2_HUMAN [Term] id: CCO:B0064787 name: DMPK_HUMAN-Phosphoserine226 def: "Protein DMPK_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:Q09013] comment: by autocatalysis; By similarity xref: UniProtKB:Q09013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:B0064788 name: DMPK_HUMAN-Phosphoserine238 def: "Protein DMPK_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q09013] comment: by autocatalysis; By similarity xref: UniProtKB:Q09013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:B0064789 name: DMPK_HUMAN-Phosphothreonine244 def: "Protein DMPK_HUMAN with the residue 244 substituted with Phosphothreonine" [UniProtKB:Q09013] comment: by autocatalysis; By similarity xref: UniProtKB:Q09013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:B0064790 name: DMWD_HUMAN-Phosphoserine545 def: "Protein DMWD_HUMAN with the residue 545 substituted with Phosphoserine" [UniProtKB:Q09019] xref: UniProtKB:Q09019 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0001726 ! DMWD_HUMAN [Term] id: CCO:B0064791 name: DNER_HUMAN-Phosphotyrosine711 def: "Protein DNER_HUMAN with the residue 711 substituted with Phosphotyrosine" [UniProtKB:Q8NFT8] comment: By similarity xref: UniProtKB:Q8NFT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057608 ! DNER_HUMAN [Term] id: CCO:B0064792 name: DNER_HUMAN-Phosphotyrosine718 def: "Protein DNER_HUMAN with the residue 718 substituted with Phosphotyrosine" [UniProtKB:Q8NFT8] comment: By similarity xref: UniProtKB:Q8NFT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004372 ! clathrin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0057608 ! DNER_HUMAN [Term] id: CCO:B0064793 name: DNER_HUMAN-Phosphotyrosine721 def: "Protein DNER_HUMAN with the residue 721 substituted with Phosphotyrosine" [UniProtKB:Q8NFT8] comment: By similarity xref: UniProtKB:Q8NFT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057608 ! DNER_HUMAN [Term] id: CCO:B0064794 name: DNJA1_HUMAN-Phosphoserine340 def: "Protein DNJA1_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:P31689] xref: UniProtKB:P31689 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:B0064795 name: DNJC1_HUMAN-Phosphoserine363 def: "Protein DNJC1_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q96KC8] comment: By similarity xref: UniProtKB:Q96KC8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058258 ! DNJC1_HUMAN [Term] id: CCO:B0064796 name: DNJC1_HUMAN-Phosphothreonine365 def: "Protein DNJC1_HUMAN with the residue 365 substituted with Phosphothreonine" [UniProtKB:Q96KC8] comment: By similarity xref: UniProtKB:Q96KC8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058258 ! DNJC1_HUMAN [Term] id: CCO:B0064797 name: DNJC1_HUMAN-Phosphoserine381 def: "Protein DNJC1_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q96KC8] xref: UniProtKB:Q96KC8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058258 ! DNJC1_HUMAN [Term] id: CCO:B0064798 name: DNJC1_HUMAN-Phosphoserine430 def: "Protein DNJC1_HUMAN with the residue 430 substituted with Phosphoserine" [UniProtKB:Q96KC8] xref: UniProtKB:Q96KC8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000200 ! ATPase activator activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004345 ! Hsp70/Hsc70 protein regulator activity relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0058258 ! DNJC1_HUMAN [Term] id: CCO:B0064799 name: DNJC1_HUMAN-Phosphoserine479 def: "Protein DNJC1_HUMAN with the residue 479 substituted with Phosphoserine" [UniProtKB:Q96KC8] comment: By similarity xref: UniProtKB:Q96KC8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058258 ! DNJC1_HUMAN [Term] id: CCO:B0064800 name: DNJC1_HUMAN-Phosphoserine480 def: "Protein DNJC1_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:Q96KC8] comment: By similarity xref: UniProtKB:Q96KC8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058258 ! DNJC1_HUMAN [Term] id: CCO:B0064801 name: DNLI1_HUMAN-Phosphoserine49 def: "Protein DNLI1_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064802 name: DNLI1_HUMAN-Phosphoserine51 def: "Protein DNLI1_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064803 name: DNLI1_HUMAN-Phosphoserine66 def: "Protein DNLI1_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000413 ! DNA ligase activity relationship: has_function CCO:F0000414 ! DNA ligase (ATP) activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064804 name: DNLI1_HUMAN-Phosphoserine76 def: "Protein DNLI1_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064805 name: DNLI1_HUMAN-Phosphoserine141 def: "Protein DNLI1_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064806 name: DNLI1_HUMAN-Phosphothreonine195 def: "Protein DNLI1_HUMAN with the residue 195 substituted with Phosphothreonine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064807 name: DNLI1_HUMAN-Phosphoserine201 def: "Protein DNLI1_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064808 name: DNLI1_HUMAN-Phosphoserine230 def: "Protein DNLI1_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064809 name: DNLI1_HUMAN-Phosphothreonine233 def: "Protein DNLI1_HUMAN with the residue 233 substituted with Phosphothreonine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064810 name: DNLI1_HUMAN-Phosphoserine911 def: "Protein DNLI1_HUMAN with the residue 911 substituted with Phosphoserine" [UniProtKB:P18858] xref: UniProtKB:P18858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001534 ! DNLI1_HUMAN [Term] id: CCO:B0064811 name: DNLI3_HUMAN-Phosphothreonine122 def: "Protein DNLI3_HUMAN with the residue 122 substituted with Phosphothreonine" [UniProtKB:P49916] comment: By similarity xref: UniProtKB:P49916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000413 ! DNA ligase activity relationship: has_function CCO:F0000414 ! DNA ligase (ATP) activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001638 ! DNLI3_HUMAN [Term] id: CCO:B0064812 name: DNLI3_HUMAN-Phosphoserine123 def: "Protein DNLI3_HUMAN with the residue 123 substituted with Phosphoserine" [UniProtKB:P49916] xref: UniProtKB:P49916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001638 ! DNLI3_HUMAN [Term] id: CCO:B0064813 name: DNLI3_HUMAN-Phosphoserine140 def: "Protein DNLI3_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P49916] xref: UniProtKB:P49916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001638 ! DNLI3_HUMAN [Term] id: CCO:B0064814 name: DNLI3_HUMAN-Phosphoserine155 def: "Protein DNLI3_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:P49916] xref: UniProtKB:P49916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001638 ! DNLI3_HUMAN [Term] id: CCO:B0064815 name: DNLI4_HUMAN-Phosphothreonine347 def: "Protein DNLI4_HUMAN with the residue 347 substituted with Phosphothreonine" [UniProtKB:P49917] xref: UniProtKB:P49917 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000413 ! DNA ligase activity relationship: has_function CCO:F0000414 ! DNA ligase (ATP) activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000506 ! DNA-dependent protein kinase complex relationship: located_in CCO:C0001480 ! DNA ligase IV complex relationship: transformation_of CCO:B0001639 ! DNLI4_HUMAN [Term] id: CCO:B0064816 name: DNM1L_HUMAN-Phosphoserine616 def: "Protein DNM1L_HUMAN with the residue 616 substituted with Phosphoserine" [UniProtKB:O00429] xref: UniProtKB:O00429 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054320 ! DNM1L_HUMAN [Term] id: CCO:B0064817 name: DNMT1_HUMAN-Phosphoserine732 def: "Protein DNMT1_HUMAN with the residue 732 substituted with Phosphoserine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0064818 name: DNMT1_HUMAN-Phosphotyrosine969 def: "Protein DNMT1_HUMAN with the residue 969 substituted with Phosphotyrosine" [UniProtKB:P26358] xref: UniProtKB:P26358 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:B0064819 name: DOCK1_HUMAN-Phosphoserine1751 def: "Protein DOCK1_HUMAN with the residue 1751 substituted with Phosphoserine" [UniProtKB:Q14185] xref: UniProtKB:Q14185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:B0064820 name: DOCK7_HUMAN-Phosphoserine30 def: "Protein DOCK7_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064821 name: DOCK7_HUMAN-Phosphoserine180 def: "Protein DOCK7_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064822 name: DOCK7_HUMAN-Phosphoserine182 def: "Protein DOCK7_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064823 name: DOCK7_HUMAN-Phosphoserine882 def: "Protein DOCK7_HUMAN with the residue 882 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064824 name: DOCK7_HUMAN-Phosphoserine888 def: "Protein DOCK7_HUMAN with the residue 888 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064825 name: DOCK7_HUMAN-Phosphoserine900 def: "Protein DOCK7_HUMAN with the residue 900 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064826 name: DOCK7_HUMAN-Phosphothreonine907 def: "Protein DOCK7_HUMAN with the residue 907 substituted with Phosphothreonine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064827 name: DOCK7_HUMAN-Phosphoserine910 def: "Protein DOCK7_HUMAN with the residue 910 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064828 name: DOCK7_HUMAN-Phosphoserine964 def: "Protein DOCK7_HUMAN with the residue 964 substituted with Phosphoserine" [UniProtKB:Q96N67] comment: By similarity xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064829 name: DOCK7_HUMAN-Phosphothreonine966 def: "Protein DOCK7_HUMAN with the residue 966 substituted with Phosphothreonine" [UniProtKB:Q96N67] comment: By similarity xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064830 name: DOCK7_HUMAN-Phosphoserine1383 def: "Protein DOCK7_HUMAN with the residue 1383 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064831 name: DOCK7_HUMAN-Phosphoserine1432 def: "Protein DOCK7_HUMAN with the residue 1432 substituted with Phosphoserine" [UniProtKB:Q96N67] xref: UniProtKB:Q96N67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0007332 ! Rac GTPase binding relationship: has_function CCO:F0008038 ! GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001897 ! basal part of cell relationship: transformation_of CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:B0064832 name: DOK1_HUMAN-Phosphoserine269 def: "Protein DOK1_HUMAN with the residue 269 substituted with Phosphoserine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064833 name: DOK1_HUMAN-Phosphoserine281 def: "Protein DOK1_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064834 name: DOK1_HUMAN-Phosphoserine291 def: "Protein DOK1_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064835 name: DOK1_HUMAN-Phosphotyrosine296 def: "Protein DOK1_HUMAN with the residue 296 substituted with Phosphotyrosine" [UniProtKB:Q99704] comment: By similarity xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064836 name: DOK1_HUMAN-Phosphotyrosine315 def: "Protein DOK1_HUMAN with the residue 315 substituted with Phosphotyrosine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064837 name: DOK1_HUMAN-Phosphotyrosine337 def: "Protein DOK1_HUMAN with the residue 337 substituted with Phosphotyrosine" [UniProtKB:Q99704] comment: By similarity xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064838 name: DOK1_HUMAN-Phosphotyrosine341 def: "Protein DOK1_HUMAN with the residue 341 substituted with Phosphotyrosine" [UniProtKB:Q99704] comment: By similarity xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064839 name: DOK1_HUMAN-Phosphotyrosine362 def: "Protein DOK1_HUMAN with the residue 362 substituted with Phosphotyrosine" [UniProtKB:Q99704] comment: by INSR; xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064840 name: DOK1_HUMAN-Phosphotyrosine377 def: "Protein DOK1_HUMAN with the residue 377 substituted with Phosphotyrosine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064841 name: DOK1_HUMAN-Phosphotyrosine398 def: "Protein DOK1_HUMAN with the residue 398 substituted with Phosphotyrosine" [UniProtKB:Q99704] comment: by INSR; xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064842 name: DOK1_HUMAN-Phosphotyrosine402 def: "Protein DOK1_HUMAN with the residue 402 substituted with Phosphotyrosine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064843 name: DOK1_HUMAN-Phosphotyrosine409 def: "Protein DOK1_HUMAN with the residue 409 substituted with Phosphotyrosine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064844 name: DOK1_HUMAN-Phosphotyrosine449 def: "Protein DOK1_HUMAN with the residue 449 substituted with Phosphotyrosine" [UniProtKB:Q99704] xref: UniProtKB:Q99704 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058443 ! DOK1_HUMAN [Term] id: CCO:B0064845 name: DOK2_HUMAN-Phosphotyrosine271 def: "Protein DOK2_HUMAN with the residue 271 substituted with Phosphotyrosine" [UniProtKB:O60496] comment: By similarity xref: UniProtKB:O60496 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001379 ! transmembrane receptor protein tyrosine kinase docking protein activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054562 ! DOK2_HUMAN [Term] id: CCO:B0064846 name: DOK2_HUMAN-Phosphotyrosine299 def: "Protein DOK2_HUMAN with the residue 299 substituted with Phosphotyrosine" [UniProtKB:O60496] xref: UniProtKB:O60496 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054562 ! DOK2_HUMAN [Term] id: CCO:B0064847 name: DOK2_HUMAN-Phosphotyrosine345 def: "Protein DOK2_HUMAN with the residue 345 substituted with Phosphotyrosine" [UniProtKB:O60496] comment: By similarity xref: UniProtKB:O60496 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054562 ! DOK2_HUMAN [Term] id: CCO:B0064848 name: DOK3_HUMAN-Phosphoserine330 def: "Protein DOK3_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q7L591] xref: UniProtKB:Q7L591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057120 ! DOK3_HUMAN [Term] id: CCO:B0064849 name: DOK3_HUMAN-Phosphotyrosine381 def: "Protein DOK3_HUMAN with the residue 381 substituted with Phosphotyrosine" [UniProtKB:Q7L591] comment: By similarity xref: UniProtKB:Q7L591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057120 ! DOK3_HUMAN [Term] id: CCO:B0064850 name: DP13A_HUMAN-Phosphothreonine399 def: "Protein DP13A_HUMAN with the residue 399 substituted with Phosphothreonine" [UniProtKB:Q9UKG1] xref: UniProtKB:Q9UKG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002219 ! DP13A_HUMAN [Term] id: CCO:B0064851 name: DPOA2_HUMAN-Phosphoserine126 def: "Protein DPOA2_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q14181] xref: UniProtKB:Q14181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:B0064852 name: DPOA2_HUMAN-Phosphoserine147 def: "Protein DPOA2_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:Q14181] xref: UniProtKB:Q14181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:B0064853 name: DPOA2_HUMAN-Phosphoserine149 def: "Protein DPOA2_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q14181] xref: UniProtKB:Q14181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:B0064854 name: DPOD3_HUMAN-Phosphoserine458 def: "Protein DPOD3_HUMAN with the residue 458 substituted with Phosphoserine" [UniProtKB:Q15054] xref: UniProtKB:Q15054 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:B0064855 name: DPOE3_HUMAN-Phosphothreonine83 def: "Protein DPOE3_HUMAN with the residue 83 substituted with Phosphothreonine" [UniProtKB:Q9NRF9] xref: UniProtKB:Q9NRF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005885 ! DPOE3_HUMAN [Term] id: CCO:B0064856 name: DPOLL_HUMAN-Phosphoserine246 def: "Protein DPOLL_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q9UGP5] xref: UniProtKB:Q9UGP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059125 ! DPOLL_HUMAN [Term] id: CCO:B0064857 name: DPOLM_HUMAN-Phosphoserine12 def: "Protein DPOLM_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q9NP87] xref: UniProtKB:Q9NP87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0000416 ! DNA nucleotidylexotransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058840 ! DPOLM_HUMAN [Term] id: CCO:B0064858 name: DPOLZ_HUMAN-Phosphothreonine582 def: "Protein DPOLZ_HUMAN with the residue 582 substituted with Phosphothreonine" [UniProtKB:O60673] xref: UniProtKB:O60673 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054574 ! DPOLZ_HUMAN [Term] id: CCO:B0064859 name: DPOLZ_HUMAN-Phosphoserine583 def: "Protein DPOLZ_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:O60673] xref: UniProtKB:O60673 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054574 ! DPOLZ_HUMAN [Term] id: CCO:B0064860 name: DPOLZ_HUMAN-Phosphothreonine2298 def: "Protein DPOLZ_HUMAN with the residue 2298 substituted with Phosphothreonine" [UniProtKB:O60673] xref: UniProtKB:O60673 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054574 ! DPOLZ_HUMAN [Term] id: CCO:B0064861 name: DPOLZ_HUMAN-Phosphoserine2522 def: "Protein DPOLZ_HUMAN with the residue 2522 substituted with Phosphoserine" [UniProtKB:O60673] xref: UniProtKB:O60673 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054574 ! DPOLZ_HUMAN [Term] id: CCO:B0064862 name: DPYL2_HUMAN-Phosphotyrosine32 def: "Protein DPYL2_HUMAN with the residue 32 substituted with Phosphotyrosine" [UniProtKB:Q16555] comment: By similarity xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064863 name: DPYL2_HUMAN-Phosphotyrosine431 def: "Protein DPYL2_HUMAN with the residue 431 substituted with Phosphotyrosine" [UniProtKB:Q16555] comment: By similarity xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064864 name: DPYL2_HUMAN-Phosphothreonine462 def: "Protein DPYL2_HUMAN with the residue 462 substituted with Phosphothreonine" [UniProtKB:Q16555] comment: By similarity xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064865 name: DPYL2_HUMAN-Phosphoserine465 def: "Protein DPYL2_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q16555] comment: By similarity xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064866 name: DPYL2_HUMAN-Phosphotyrosine499 def: "Protein DPYL2_HUMAN with the residue 499 substituted with Phosphotyrosine" [UniProtKB:Q16555] comment: By similarity xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064867 name: DPYL2_HUMAN-Phosphothreonine509 def: "Protein DPYL2_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q16555] xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064868 name: DPYL2_HUMAN-Phosphothreonine514 def: "Protein DPYL2_HUMAN with the residue 514 substituted with Phosphothreonine" [UniProtKB:Q16555] comment: in vitro; xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064869 name: DPYL2_HUMAN-Phosphoserine518 def: "Protein DPYL2_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:Q16555] xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000628 ! dihydropyrimidinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064870 name: DPYL2_HUMAN-Phosphoserine522 def: "Protein DPYL2_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q16555] xref: UniProtKB:Q16555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:B0064871 name: DPYL3_HUMAN-Phosphotyrosine499 def: "Protein DPYL3_HUMAN with the residue 499 substituted with Phosphotyrosine" [UniProtKB:Q14195] comment: By similarity xref: UniProtKB:Q14195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055970 ! DPYL3_HUMAN [Term] id: CCO:B0064872 name: DPYL3_HUMAN-Phosphothreonine509 def: "Protein DPYL3_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q14195] comment: By similarity xref: UniProtKB:Q14195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055970 ! DPYL3_HUMAN [Term] id: CCO:B0064873 name: DPYL3_HUMAN-Phosphoserine522 def: "Protein DPYL3_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q14195] xref: UniProtKB:Q14195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055970 ! DPYL3_HUMAN [Term] id: CCO:B0064874 name: DPYL3_HUMAN-Phosphoserine551 def: "Protein DPYL3_HUMAN with the residue 551 substituted with Phosphoserine" [UniProtKB:Q14195] xref: UniProtKB:Q14195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000628 ! dihydropyrimidinase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0055970 ! DPYL3_HUMAN [Term] id: CCO:B0064875 name: DPYL5_HUMAN-Phosphothreonine509 def: "Protein DPYL5_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q9BPU6] xref: UniProtKB:Q9BPU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058468 ! DPYL5_HUMAN [Term] id: CCO:B0064876 name: DPYL5_HUMAN-Phosphothreonine514 def: "Protein DPYL5_HUMAN with the residue 514 substituted with Phosphothreonine" [UniProtKB:Q9BPU6] xref: UniProtKB:Q9BPU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058468 ! DPYL5_HUMAN [Term] id: CCO:B0064877 name: DPYL5_HUMAN-Phosphothreonine516 def: "Protein DPYL5_HUMAN with the residue 516 substituted with Phosphothreonine" [UniProtKB:Q9BPU6] xref: UniProtKB:Q9BPU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058468 ! DPYL5_HUMAN [Term] id: CCO:B0064878 name: DPYL5_HUMAN-Phosphoserine534 def: "Protein DPYL5_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:Q9BPU6] xref: UniProtKB:Q9BPU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058468 ! DPYL5_HUMAN [Term] id: CCO:B0064879 name: DREB_HUMAN-Phosphothreonine331 def: "Protein DREB_HUMAN with the residue 331 substituted with Phosphothreonine" [UniProtKB:Q16643] xref: UniProtKB:Q16643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001653 ! profilin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001674 ! actomyosin relationship: transformation_of CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:B0064880 name: DRG2_HUMAN-Phosphoserine199 def: "Protein DRG2_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:P55039] comment: By similarity xref: UniProtKB:P55039 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055522 ! DRG2_HUMAN [Term] id: CCO:B0064881 name: DSN1_HUMAN-Phosphoserine77 def: "Protein DSN1_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q9H410] xref: UniProtKB:Q9H410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002134 ! DSN1_HUMAN [Term] id: CCO:B0064882 name: DSN1_HUMAN-Phosphoserine81 def: "Protein DSN1_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:Q9H410] xref: UniProtKB:Q9H410 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000092 ! MIS12/MIND type complex relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002134 ! DSN1_HUMAN [Term] id: CCO:B0064883 name: DSRAD_HUMAN-Phosphothreonine601 def: "Protein DSRAD_HUMAN with the residue 601 substituted with Phosphothreonine" [UniProtKB:P55265] xref: UniProtKB:P55265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055532 ! DSRAD_HUMAN [Term] id: CCO:B0064884 name: DSRAD_HUMAN-Phosphoserine614 def: "Protein DSRAD_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:P55265] xref: UniProtKB:P55265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055532 ! DSRAD_HUMAN [Term] id: CCO:B0064885 name: DSRAD_HUMAN-Phosphothreonine808 def: "Protein DSRAD_HUMAN with the residue 808 substituted with Phosphothreonine" [UniProtKB:P55265] xref: UniProtKB:P55265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000311 ! double-stranded RNA adenosine deaminase activity relationship: has_function CCO:F0000485 ! adenosine deaminase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055532 ! DSRAD_HUMAN [Term] id: CCO:B0064886 name: DSRAD_HUMAN-Phosphothreonine818 def: "Protein DSRAD_HUMAN with the residue 818 substituted with Phosphothreonine" [UniProtKB:P55265] xref: UniProtKB:P55265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055532 ! DSRAD_HUMAN [Term] id: CCO:B0064887 name: DSRAD_HUMAN-Phosphoserine823 def: "Protein DSRAD_HUMAN with the residue 823 substituted with Phosphoserine" [UniProtKB:P55265] xref: UniProtKB:P55265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055532 ! DSRAD_HUMAN [Term] id: CCO:B0064888 name: DSRAD_HUMAN-Phosphoserine825 def: "Protein DSRAD_HUMAN with the residue 825 substituted with Phosphoserine" [UniProtKB:P55265] xref: UniProtKB:P55265 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055532 ! DSRAD_HUMAN [Term] id: CCO:B0064889 name: DTBP1_HUMAN-Phosphoserine316 def: "Protein DTBP1_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q96EV8] xref: UniProtKB:Q96EV8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005258 ! DTBP1_HUMAN [Term] id: CCO:B0064890 name: DTBP1_HUMAN-Phosphoserine321 def: "Protein DTBP1_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q96EV8] xref: UniProtKB:Q96EV8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001638 ! sarcolemma relationship: transformation_of CCO:B0005258 ! DTBP1_HUMAN [Term] id: CCO:B0064891 name: DTL_HUMAN-Phosphoserine485 def: "Protein DTL_HUMAN with the residue 485 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064892 name: DTL_HUMAN-Phosphoserine490 def: "Protein DTL_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064893 name: DTL_HUMAN-Phosphoserine495 def: "Protein DTL_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064894 name: DTL_HUMAN-Phosphoserine510 def: "Protein DTL_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064895 name: DTL_HUMAN-Phosphoserine512 def: "Protein DTL_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064896 name: DTL_HUMAN-Phosphoserine557 def: "Protein DTL_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064897 name: DTL_HUMAN-Phosphoserine676 def: "Protein DTL_HUMAN with the residue 676 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064898 name: DTL_HUMAN-Phosphoserine679 def: "Protein DTL_HUMAN with the residue 679 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064899 name: DTL_HUMAN-Phosphoserine681 def: "Protein DTL_HUMAN with the residue 681 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064900 name: DTL_HUMAN-Phosphoserine682 def: "Protein DTL_HUMAN with the residue 682 substituted with Phosphoserine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064901 name: DTL_HUMAN-Phosphothreonine684 def: "Protein DTL_HUMAN with the residue 684 substituted with Phosphothreonine" [UniProtKB:Q9NZJ0] xref: UniProtKB:Q9NZJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:B0064902 name: DTX2_HUMAN-Phosphoserine360 def: "Protein DTX2_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q86UW9] xref: UniProtKB:Q86UW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:B0064903 name: DTX4_HUMAN-Phosphoserine376 def: "Protein DTX4_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q9Y2E6] xref: UniProtKB:Q9Y2E6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059301 ! DTX4_HUMAN [Term] id: CCO:B0064904 name: DUS10_HUMAN-Phosphoserine4 def: "Protein DUS10_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:Q9Y6W6] xref: UniProtKB:Q9Y6W6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059419 ! DUS10_HUMAN [Term] id: CCO:B0064905 name: DUS16_HUMAN-Phosphoserine501 def: "Protein DUS16_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q9BY84] xref: UniProtKB:Q9BY84 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037152 ! DUS16_HUMAN [Term] id: CCO:B0064906 name: DUS6_HUMAN-Phosphoserine331 def: "Protein DUS6_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q16828] xref: UniProtKB:Q16828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001087 ! protein serine/threonine phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003513 ! MAP kinase tyrosine/serine/threonine phosphatase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001824 ! DUS6_HUMAN [Term] id: CCO:B0064907 name: DUT_HUMAN-Phosphoserine99 def: "Protein DUT_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:P33316] xref: UniProtKB:P33316 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055266 ! DUT_HUMAN [Term] id: CCO:B0064908 name: DYR1B_HUMAN-Phosphotyrosine271 def: "Protein DYR1B_HUMAN with the residue 271 substituted with Phosphotyrosine" [UniProtKB:Q9Y463] comment: by autocatalysis; xref: UniProtKB:Q9Y463 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:B0064909 name: DYR1B_HUMAN-Phosphotyrosine273 def: "Protein DYR1B_HUMAN with the residue 273 substituted with Phosphotyrosine" [UniProtKB:Q9Y463] comment: by autocatalysis; xref: UniProtKB:Q9Y463 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:B0064910 name: DYRK2_HUMAN-Phosphotyrosine382 def: "Protein DYRK2_HUMAN with the residue 382 substituted with Phosphotyrosine" [UniProtKB:Q92630] xref: UniProtKB:Q92630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005265 ! DYRK2_HUMAN [Term] id: CCO:B0064911 name: E2AK4_HUMAN-Phosphoserine230 def: "Protein E2AK4_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q9P2K8] xref: UniProtKB:Q9P2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001061 ! eukaryotic translation initiation factor 2alpha kinase activity relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0002088 ! cytosolic ribosome relationship: transformation_of CCO:B0059059 ! E2AK4_HUMAN [Term] id: CCO:B0064912 name: E2AK4_HUMAN-Phosphothreonine667 def: "Protein E2AK4_HUMAN with the residue 667 substituted with Phosphothreonine" [UniProtKB:Q9P2K8] xref: UniProtKB:Q9P2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059059 ! E2AK4_HUMAN [Term] id: CCO:B0064913 name: E2AK4_HUMAN-Phosphothreonine899 def: "Protein E2AK4_HUMAN with the residue 899 substituted with Phosphothreonine" [UniProtKB:Q9P2K8] comment: by autocatalysis; By similarity xref: UniProtKB:Q9P2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059059 ! E2AK4_HUMAN [Term] id: CCO:B0064914 name: E2AK4_HUMAN-Phosphothreonine904 def: "Protein E2AK4_HUMAN with the residue 904 substituted with Phosphothreonine" [UniProtKB:Q9P2K8] comment: by autocatalysis; By similarity xref: UniProtKB:Q9P2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059059 ! E2AK4_HUMAN [Term] id: CCO:B0064915 name: E2F7_HUMAN-Phosphoserine410 def: "Protein E2F7_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q96AV8] xref: UniProtKB:Q96AV8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002031 ! E2F7_HUMAN [Term] id: CCO:B0064916 name: EAF2_HUMAN-Phosphoserine146 def: "Protein EAF2_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q96CJ1] xref: UniProtKB:Q96CJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058183 ! EAF2_HUMAN [Term] id: CCO:B0064917 name: EAF2_HUMAN-Phosphoserine151 def: "Protein EAF2_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q96CJ1] xref: UniProtKB:Q96CJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058183 ! EAF2_HUMAN [Term] id: CCO:B0064918 name: EAF2_HUMAN-Phosphoserine154 def: "Protein EAF2_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q96CJ1] xref: UniProtKB:Q96CJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058183 ! EAF2_HUMAN [Term] id: CCO:B0064919 name: EDAR_HUMAN-Phosphoserine324 def: "Protein EDAR_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:Q9UNE0] comment: By similarity xref: UniProtKB:Q9UNE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059250 ! EDAR_HUMAN [Term] id: CCO:B0064920 name: EDC4_HUMAN-Phosphoserine809 def: "Protein EDC4_HUMAN with the residue 809 substituted with Phosphoserine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0064921 name: EDC4_HUMAN-Phosphothreonine821 def: "Protein EDC4_HUMAN with the residue 821 substituted with Phosphothreonine" [UniProtKB:Q6P2E9] xref: UniProtKB:Q6P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:B0064922 name: EF1A1_HUMAN-Phosphotyrosine86 def: "Protein EF1A1_HUMAN with the residue 86 substituted with Phosphotyrosine" [UniProtKB:P68104] xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0064923 name: EF1A1_HUMAN-Phosphotyrosine141 def: "Protein EF1A1_HUMAN with the residue 141 substituted with Phosphotyrosine" [UniProtKB:P68104] xref: UniProtKB:P68104 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:B0064924 name: EF1D_HUMAN-N-acetylalanine2 def: "Protein EF1D_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P29692] xref: UniProtKB:P29692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:B0064925 name: EF1D_HUMAN-Phosphoserine60 def: "Protein EF1D_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:P29692] xref: UniProtKB:P29692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:B0064926 name: EF1D_HUMAN-Phosphoserine119 def: "Protein EF1D_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:P29692] xref: UniProtKB:P29692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:B0064927 name: EF1D_HUMAN-Phosphothreonine129 def: "Protein EF1D_HUMAN with the residue 129 substituted with Phosphothreonine" [UniProtKB:P29692] xref: UniProtKB:P29692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:B0064928 name: EF1D_HUMAN-Phosphoserine133 def: "Protein EF1D_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:P29692] xref: UniProtKB:P29692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:B0064929 name: EF1D_HUMAN-Phosphothreonine147 def: "Protein EF1D_HUMAN with the residue 147 substituted with Phosphothreonine" [UniProtKB:P29692] xref: UniProtKB:P29692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:B0064930 name: EF1D_HUMAN-Phosphoserine162 def: "Protein EF1D_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:P29692] xref: UniProtKB:P29692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:B0064931 name: EGFR_HUMAN-Phosphotyrosine869 def: "Protein EGFR_HUMAN with the residue 869 substituted with Phosphotyrosine" [UniProtKB:P00533] xref: UniProtKB:P00533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001462 ! EGFR_HUMAN [Term] id: CCO:B0064932 name: EHF_HUMAN-Phosphoserine242 def: "Protein EHF_HUMAN with the residue 242 substituted with Phosphoserine" [UniProtKB:Q9NZC4] xref: UniProtKB:Q9NZC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058991 ! EHF_HUMAN [Term] id: CCO:B0064933 name: EI24_HUMAN-Phosphoserine75 def: "Protein EI24_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:O14681] xref: UniProtKB:O14681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054365 ! EI24_HUMAN [Term] id: CCO:B0064934 name: EI24_HUMAN-Phosphoserine337 def: "Protein EI24_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:O14681] comment: By similarity xref: UniProtKB:O14681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054365 ! EI24_HUMAN [Term] id: CCO:B0064935 name: EI24_HUMAN-Phosphoserine345 def: "Protein EI24_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:O14681] xref: UniProtKB:O14681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054365 ! EI24_HUMAN [Term] id: CCO:B0064936 name: EI24_HUMAN-Phosphoserine349 def: "Protein EI24_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:O14681] xref: UniProtKB:O14681 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054365 ! EI24_HUMAN [Term] id: CCO:B0064937 name: EI2BD_HUMAN-Phosphothreonine86 def: "Protein EI2BD_HUMAN with the residue 86 substituted with Phosphothreonine" [UniProtKB:Q9UI10] xref: UniProtKB:Q9UI10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000417 ! eukaryotic translation initiation factor 2B complex relationship: transformation_of CCO:B0059154 ! EI2BD_HUMAN [Term] id: CCO:B0064938 name: EI2BE_HUMAN-Phosphoserine525 def: "Protein EI2BE_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004653 ! translation initiation factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000417 ! eukaryotic translation initiation factor 2B complex relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064939 name: EI2BE_HUMAN-Phosphoserine527 def: "Protein EI2BE_HUMAN with the residue 527 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064940 name: EI2BE_HUMAN-Phosphoserine529 def: "Protein EI2BE_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064941 name: EI2BE_HUMAN-Phosphoserine532 def: "Protein EI2BE_HUMAN with the residue 532 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064942 name: EI2BE_HUMAN-Phosphoserine535 def: "Protein EI2BE_HUMAN with the residue 535 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064943 name: EI2BE_HUMAN-Phosphoserine540 def: "Protein EI2BE_HUMAN with the residue 540 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064944 name: EI2BE_HUMAN-Phosphoserine544 def: "Protein EI2BE_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064945 name: EI2BE_HUMAN-Phosphoserine717 def: "Protein EI2BE_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064946 name: EI2BE_HUMAN-Phosphoserine718 def: "Protein EI2BE_HUMAN with the residue 718 substituted with Phosphoserine" [UniProtKB:Q13144] xref: UniProtKB:Q13144 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:B0064947 name: EIF1_HUMAN-Phosphotyrosine30 def: "Protein EIF1_HUMAN with the residue 30 substituted with Phosphotyrosine" [UniProtKB:P41567] xref: UniProtKB:P41567 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0019928 ! EIF1_HUMAN [Term] id: CCO:B0064948 name: EIF2A_HUMAN-Phosphoserine506 def: "Protein EIF2A_HUMAN with the residue 506 substituted with Phosphoserine" [UniProtKB:Q9BY44] xref: UniProtKB:Q9BY44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058570 ! EIF2A_HUMAN [Term] id: CCO:B0064949 name: EIF2A_HUMAN-Phosphothreonine512 def: "Protein EIF2A_HUMAN with the residue 512 substituted with Phosphothreonine" [UniProtKB:Q9BY44] xref: UniProtKB:Q9BY44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0005784 ! ribosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000416 ! eukaryotic translation initiation factor 2 complex relationship: transformation_of CCO:B0058570 ! EIF2A_HUMAN [Term] id: CCO:B0064950 name: EIF2A_HUMAN-Phosphoserine517 def: "Protein EIF2A_HUMAN with the residue 517 substituted with Phosphoserine" [UniProtKB:Q9BY44] xref: UniProtKB:Q9BY44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058570 ! EIF2A_HUMAN [Term] id: CCO:B0064951 name: EIF2A_HUMAN-Phosphothreonine518 def: "Protein EIF2A_HUMAN with the residue 518 substituted with Phosphothreonine" [UniProtKB:Q9BY44] xref: UniProtKB:Q9BY44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058570 ! EIF2A_HUMAN [Term] id: CCO:B0064952 name: EIF2A_HUMAN-Phosphothreonine522 def: "Protein EIF2A_HUMAN with the residue 522 substituted with Phosphothreonine" [UniProtKB:Q9BY44] xref: UniProtKB:Q9BY44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058570 ! EIF2A_HUMAN [Term] id: CCO:B0064953 name: EIF3A_HUMAN-Phosphotyrosine382 def: "Protein EIF3A_HUMAN with the residue 382 substituted with Phosphotyrosine" [UniProtKB:Q14152] xref: UniProtKB:Q14152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055965 ! EIF3A_HUMAN [Term] id: CCO:B0064954 name: EIF3A_HUMAN-Phosphoserine584 def: "Protein EIF3A_HUMAN with the residue 584 substituted with Phosphoserine" [UniProtKB:Q14152] xref: UniProtKB:Q14152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0055965 ! EIF3A_HUMAN [Term] id: CCO:B0064955 name: EIF3A_HUMAN-Phosphoserine1336 def: "Protein EIF3A_HUMAN with the residue 1336 substituted with Phosphoserine" [UniProtKB:Q14152] xref: UniProtKB:Q14152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055965 ! EIF3A_HUMAN [Term] id: CCO:B0064956 name: EIF3B_HUMAN-Phosphoserine78 def: "Protein EIF3B_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0064957 name: EIF3B_HUMAN-Phosphoserine81 def: "Protein EIF3B_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0064958 name: EIF3B_HUMAN-Phosphoserine239 def: "Protein EIF3B_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:P55884] xref: UniProtKB:P55884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026275 ! EIF3B_HUMAN [Term] id: CCO:B0064959 name: EIF3C_HUMAN-Phosphothreonine6 def: "Protein EIF3C_HUMAN with the residue 6 substituted with Phosphothreonine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0064960 name: EIF3C_HUMAN-Phosphoserine9 def: "Protein EIF3C_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0064961 name: EIF3C_HUMAN-Phosphoserine11 def: "Protein EIF3C_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0064962 name: EIF3C_HUMAN-Phosphoserine13 def: "Protein EIF3C_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0064963 name: EIF3C_HUMAN-Phosphoserine15 def: "Protein EIF3C_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0064964 name: EIF3C_HUMAN-Phosphoserine16 def: "Protein EIF3C_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0064965 name: EIF3C_HUMAN-Phosphoserine18 def: "Protein EIF3C_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q99613] xref: UniProtKB:Q99613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026271 ! EIF3C_HUMAN [Term] id: CCO:B0064966 name: EIF3E_HUMAN-Phosphoserine399 def: "Protein EIF3E_HUMAN with the residue 399 substituted with Phosphoserine" [UniProtKB:P60228] xref: UniProtKB:P60228 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:B0064967 name: EIF3H_HUMAN-Phosphothreonine8 def: "Protein EIF3H_HUMAN with the residue 8 substituted with Phosphothreonine" [UniProtKB:O15372] xref: UniProtKB:O15372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:B0064968 name: EIF3H_HUMAN-Phosphoserine10 def: "Protein EIF3H_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:O15372] xref: UniProtKB:O15372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:B0064969 name: EIF3H_HUMAN-Phosphothreonine11 def: "Protein EIF3H_HUMAN with the residue 11 substituted with Phosphothreonine" [UniProtKB:O15372] xref: UniProtKB:O15372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:B0064970 name: EIF3H_HUMAN-Phosphoserine183 def: "Protein EIF3H_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:O15372] xref: UniProtKB:O15372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000418 ! eukaryotic translation initiation factor 3 complex relationship: transformation_of CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:B0064971 name: ELAV1_HUMAN-Phosphoserine202 def: "Protein ELAV1_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q15717] xref: UniProtKB:Q15717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056099 ! ELAV1_HUMAN [Term] id: CCO:B0064972 name: ELAV1_HUMAN-arginine217 def: "Protein ELAV1_HUMAN with the residue 217 substituted with arginine" [UniProtKB:Q15717] comment: by CARM1; xref: UniProtKB:Q15717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000313 ! mRNA binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056099 ! ELAV1_HUMAN [Term] id: CCO:B0064973 name: ELAV2_HUMAN-Phosphoserine221 def: "Protein ELAV2_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q12926] xref: UniProtKB:Q12926 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055858 ! ELAV2_HUMAN [Term] id: CCO:B0064974 name: ELF1_HUMAN-Phosphoserine163 def: "Protein ELF1_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:P32519] xref: UniProtKB:P32519 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006027 ! ELF1_HUMAN [Term] id: CCO:B0064975 name: ELF2_HUMAN-Phosphoserine191 def: "Protein ELF2_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q15723] xref: UniProtKB:Q15723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056101 ! ELF2_HUMAN [Term] id: CCO:B0064976 name: ELF2_HUMAN-Phosphoserine363 def: "Protein ELF2_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q15723] xref: UniProtKB:Q15723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056101 ! ELF2_HUMAN [Term] id: CCO:B0064977 name: ELF2_HUMAN-Phosphoserine372 def: "Protein ELF2_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q15723] xref: UniProtKB:Q15723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056101 ! ELF2_HUMAN [Term] id: CCO:B0064978 name: ELF4_HUMAN-Phosphoserine151 def: "Protein ELF4_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q99607] xref: UniProtKB:Q99607 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058430 ! ELF4_HUMAN [Term] id: CCO:B0064979 name: ELF4_HUMAN-Phosphothreonine643 def: "Protein ELF4_HUMAN with the residue 643 substituted with Phosphothreonine" [UniProtKB:Q99607] xref: UniProtKB:Q99607 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0058430 ! ELF4_HUMAN [Term] id: CCO:B0064980 name: ELF4_HUMAN-Phosphoserine648 def: "Protein ELF4_HUMAN with the residue 648 substituted with Phosphoserine" [UniProtKB:Q99607] xref: UniProtKB:Q99607 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058430 ! ELF4_HUMAN [Term] id: CCO:B0064981 name: ELK3_HUMAN-Phosphoserine245 def: "Protein ELK3_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:P41970] xref: UniProtKB:P41970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055345 ! ELK3_HUMAN [Term] id: CCO:B0064982 name: ELL_HUMAN-Phosphothreonine170 def: "Protein ELL_HUMAN with the residue 170 substituted with Phosphothreonine" [UniProtKB:P55199] xref: UniProtKB:P55199 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055529 ! ELL_HUMAN [Term] id: CCO:B0064983 name: ELL_HUMAN-Phosphoserine309 def: "Protein ELL_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:P55199] xref: UniProtKB:P55199 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055529 ! ELL_HUMAN [Term] id: CCO:B0064984 name: ELL_HUMAN-Phosphoserine561 def: "Protein ELL_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:P55199] xref: UniProtKB:P55199 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055529 ! ELL_HUMAN [Term] id: CCO:B0064985 name: ELN_HUMAN-Hydroxyproline34 def: "Protein ELN_HUMAN with the residue 34 substituted with Hydroxyproline" [UniProtKB:P15502] xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064986 name: ELN_HUMAN-Hydroxyproline65 def: "Protein ELN_HUMAN with the residue 65 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064987 name: ELN_HUMAN-Hydroxyproline67 def: "Protein ELN_HUMAN with the residue 67 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064988 name: ELN_HUMAN-Hydroxyproline88 def: "Protein ELN_HUMAN with the residue 88 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064989 name: ELN_HUMAN-Allysine104 def: "Protein ELN_HUMAN with the residue 104 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064990 name: ELN_HUMAN-4-hydroxyproline116 def: "Protein ELN_HUMAN with the residue 116 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064991 name: ELN_HUMAN-Hydroxyproline156 def: "Protein ELN_HUMAN with the residue 156 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064992 name: ELN_HUMAN-Hydroxyproline167 def: "Protein ELN_HUMAN with the residue 167 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064993 name: ELN_HUMAN-Hydroxyproline170 def: "Protein ELN_HUMAN with the residue 170 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064994 name: ELN_HUMAN-Hydroxyproline177 def: "Protein ELN_HUMAN with the residue 177 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064995 name: ELN_HUMAN-4-hydroxyproline190 def: "Protein ELN_HUMAN with the residue 190 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064996 name: ELN_HUMAN-Allysine241 def: "Protein ELN_HUMAN with the residue 241 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064997 name: ELN_HUMAN-Allysine261 def: "Protein ELN_HUMAN with the residue 261 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064998 name: ELN_HUMAN-Allysine265 def: "Protein ELN_HUMAN with the residue 265 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0064999 name: ELN_HUMAN-4-hydroxyproline283 def: "Protein ELN_HUMAN with the residue 283 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065000 name: ELN_HUMAN-4-hydroxyproline286 def: "Protein ELN_HUMAN with the residue 286 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065001 name: ELN_HUMAN-Hydroxyproline290 def: "Protein ELN_HUMAN with the residue 290 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065002 name: ELN_HUMAN-Allysine312 def: "Protein ELN_HUMAN with the residue 312 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065003 name: ELN_HUMAN-Allysine315 def: "Protein ELN_HUMAN with the residue 315 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065004 name: ELN_HUMAN-4-hydroxyproline327 def: "Protein ELN_HUMAN with the residue 327 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065005 name: ELN_HUMAN-4-hydroxyproline342 def: "Protein ELN_HUMAN with the residue 342 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065006 name: ELN_HUMAN-4-hydroxyproline347 def: "Protein ELN_HUMAN with the residue 347 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065007 name: ELN_HUMAN-Hydroxyproline352 def: "Protein ELN_HUMAN with the residue 352 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065008 name: ELN_HUMAN-Hydroxyproline355 def: "Protein ELN_HUMAN with the residue 355 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065009 name: ELN_HUMAN-4-hydroxyproline360 def: "Protein ELN_HUMAN with the residue 360 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065010 name: ELN_HUMAN-Allysine375 def: "Protein ELN_HUMAN with the residue 375 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065011 name: ELN_HUMAN-Allysine379 def: "Protein ELN_HUMAN with the residue 379 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065012 name: ELN_HUMAN-Allysine382 def: "Protein ELN_HUMAN with the residue 382 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065013 name: ELN_HUMAN-4-hydroxyproline415 def: "Protein ELN_HUMAN with the residue 415 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065014 name: ELN_HUMAN-Hydroxyproline421 def: "Protein ELN_HUMAN with the residue 421 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065015 name: ELN_HUMAN-4-hydroxyproline427 def: "Protein ELN_HUMAN with the residue 427 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065016 name: ELN_HUMAN-Allysine451 def: "Protein ELN_HUMAN with the residue 451 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065017 name: ELN_HUMAN-Hydroxyproline465 def: "Protein ELN_HUMAN with the residue 465 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065018 name: ELN_HUMAN-Hydroxyproline467 def: "Protein ELN_HUMAN with the residue 467 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065019 name: ELN_HUMAN-4-hydroxyproline481 def: "Protein ELN_HUMAN with the residue 481 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065020 name: ELN_HUMAN-Allysine492 def: "Protein ELN_HUMAN with the residue 492 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065021 name: ELN_HUMAN-Allysine496 def: "Protein ELN_HUMAN with the residue 496 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065022 name: ELN_HUMAN-Hydroxyproline522 def: "Protein ELN_HUMAN with the residue 522 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065023 name: ELN_HUMAN-Hydroxyproline550 def: "Protein ELN_HUMAN with the residue 550 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065024 name: ELN_HUMAN-Allysine558 def: "Protein ELN_HUMAN with the residue 558 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065025 name: ELN_HUMAN-Allysine562 def: "Protein ELN_HUMAN with the residue 562 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065026 name: ELN_HUMAN-Allysine566 def: "Protein ELN_HUMAN with the residue 566 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065027 name: ELN_HUMAN-4-hydroxyproline580 def: "Protein ELN_HUMAN with the residue 580 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065028 name: ELN_HUMAN-4-hydroxyproline589 def: "Protein ELN_HUMAN with the residue 589 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: Probable xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065029 name: ELN_HUMAN-4-hydroxyproline598 def: "Protein ELN_HUMAN with the residue 598 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: Probable xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065030 name: ELN_HUMAN-4-hydroxyproline607 def: "Protein ELN_HUMAN with the residue 607 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065031 name: ELN_HUMAN-Hydroxyproline646 def: "Protein ELN_HUMAN with the residue 646 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065032 name: ELN_HUMAN-Allysine653 def: "Protein ELN_HUMAN with the residue 653 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065033 name: ELN_HUMAN-Allysine656 def: "Protein ELN_HUMAN with the residue 656 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065034 name: ELN_HUMAN-4-hydroxyproline677 def: "Protein ELN_HUMAN with the residue 677 substituted with 4-hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001487 ! extracellular matrix structural constituent relationship: has_function CCO:F0004318 ! extracellular matrix constituent conferring elasticity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065035 name: ELN_HUMAN-Allysine693 def: "Protein ELN_HUMAN with the residue 693 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065036 name: ELN_HUMAN-Allysine697 def: "Protein ELN_HUMAN with the residue 697 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065037 name: ELN_HUMAN-Allysine735 def: "Protein ELN_HUMAN with the residue 735 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065038 name: ELN_HUMAN-Allysine738 def: "Protein ELN_HUMAN with the residue 738 substituted with Allysine" [UniProtKB:P15502] comment: By similarity xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065039 name: ELN_HUMAN-Hydroxyproline769 def: "Protein ELN_HUMAN with the residue 769 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065040 name: ELN_HUMAN-Hydroxyproline772 def: "Protein ELN_HUMAN with the residue 772 substituted with Hydroxyproline" [UniProtKB:P15502] comment: partial; xref: UniProtKB:P15502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055038 ! ELN_HUMAN [Term] id: CCO:B0065041 name: ELOA1_HUMAN-Phosphoserine125 def: "Protein ELOA1_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q14241] xref: UniProtKB:Q14241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003481 ! RNA polymerase II transcription elongation factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055974 ! ELOA1_HUMAN [Term] id: CCO:B0065042 name: ELOA1_HUMAN-Phosphoserine137 def: "Protein ELOA1_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q14241] xref: UniProtKB:Q14241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055974 ! ELOA1_HUMAN [Term] id: CCO:B0065043 name: ELP3_HUMAN-Phosphotyrosine202 def: "Protein ELP3_HUMAN with the residue 202 substituted with Phosphotyrosine" [UniProtKB:Q9H9T3] xref: UniProtKB:Q9H9T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0002009 ! phosphorylase kinase regulator activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003481 ! RNA polymerase II transcription elongation factor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: located_in CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme relationship: transformation_of CCO:B0058757 ! ELP3_HUMAN [Term] id: CCO:B0065044 name: ELP4_HUMAN-Phosphoserine37 def: "Protein ELP4_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q96EB1] xref: UniProtKB:Q96EB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058203 ! ELP4_HUMAN [Term] id: CCO:B0065045 name: ELP4_HUMAN-Phosphoserine42 def: "Protein ELP4_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q96EB1] xref: UniProtKB:Q96EB1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000815 ! H3/H4 histone acetyltransferase activity relationship: has_function CCO:F0002009 ! phosphorylase kinase regulator activity relationship: has_function CCO:F0003481 ! RNA polymerase II transcription elongation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: located_in CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme relationship: located_in CCO:C0001582 ! Elongator holoenzyme complex relationship: transformation_of CCO:B0058203 ! ELP4_HUMAN [Term] id: CCO:B0065046 name: EM55_HUMAN-Phosphoserine19 def: "Protein EM55_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q00013] comment: By similarity xref: UniProtKB:Q00013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000802 ! guanylate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0019045 ! EM55_HUMAN [Term] id: CCO:B0065047 name: EM55_HUMAN-Phosphothreonine49 def: "Protein EM55_HUMAN with the residue 49 substituted with Phosphothreonine" [UniProtKB:Q00013] xref: UniProtKB:Q00013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019045 ! EM55_HUMAN [Term] id: CCO:B0065048 name: EM55_HUMAN-Phosphoserine57 def: "Protein EM55_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:Q00013] xref: UniProtKB:Q00013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019045 ! EM55_HUMAN [Term] id: CCO:B0065049 name: EM55_HUMAN-Phosphoserine243 def: "Protein EM55_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:Q00013] xref: UniProtKB:Q00013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019045 ! EM55_HUMAN [Term] id: CCO:B0065050 name: EMAL4_HUMAN-Phosphoserine895 def: "Protein EMAL4_HUMAN with the residue 895 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065051 name: EMAL4_HUMAN-Phosphothreonine897 def: "Protein EMAL4_HUMAN with the residue 897 substituted with Phosphothreonine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065052 name: EMAL4_HUMAN-Phosphoserine903 def: "Protein EMAL4_HUMAN with the residue 903 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065053 name: EMAL4_HUMAN-Phosphothreonine909 def: "Protein EMAL4_HUMAN with the residue 909 substituted with Phosphothreonine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065054 name: EMAL4_HUMAN-Phosphothreonine921 def: "Protein EMAL4_HUMAN with the residue 921 substituted with Phosphothreonine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065055 name: EMAL4_HUMAN-Phosphoserine934 def: "Protein EMAL4_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065056 name: EMAL4_HUMAN-Phosphoserine942 def: "Protein EMAL4_HUMAN with the residue 942 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065057 name: EMAL4_HUMAN-Phosphoserine946 def: "Protein EMAL4_HUMAN with the residue 946 substituted with Phosphoserine" [UniProtKB:Q9HC35] xref: UniProtKB:Q9HC35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002144 ! EMAL4_HUMAN [Term] id: CCO:B0065058 name: EMR3_HUMAN-Phosphoserine141 def: "Protein EMR3_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q9BY15] xref: UniProtKB:Q9BY15 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058565 ! EMR3_HUMAN [Term] id: CCO:B0065059 name: EMR3_HUMAN-Phosphothreonine175 def: "Protein EMR3_HUMAN with the residue 175 substituted with Phosphothreonine" [UniProtKB:Q9BY15] xref: UniProtKB:Q9BY15 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058565 ! EMR3_HUMAN [Term] id: CCO:B0065060 name: EMSY_HUMAN-Phosphoserine209 def: "Protein EMSY_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q7Z589] xref: UniProtKB:Q7Z589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057175 ! EMSY_HUMAN [Term] id: CCO:B0065061 name: EMSY_HUMAN-Phosphoserine238 def: "Protein EMSY_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q7Z589] xref: UniProtKB:Q7Z589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057175 ! EMSY_HUMAN [Term] id: CCO:B0065062 name: EMSY_HUMAN-Phosphothreonine262 def: "Protein EMSY_HUMAN with the residue 262 substituted with Phosphothreonine" [UniProtKB:Q7Z589] xref: UniProtKB:Q7Z589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057175 ! EMSY_HUMAN [Term] id: CCO:B0065063 name: EMSY_HUMAN-Phosphothreonine273 def: "Protein EMSY_HUMAN with the residue 273 substituted with Phosphothreonine" [UniProtKB:Q7Z589] xref: UniProtKB:Q7Z589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057175 ! EMSY_HUMAN [Term] id: CCO:B0065064 name: EMSY_HUMAN-Phosphothreonine274 def: "Protein EMSY_HUMAN with the residue 274 substituted with Phosphothreonine" [UniProtKB:Q7Z589] xref: UniProtKB:Q7Z589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057175 ! EMSY_HUMAN [Term] id: CCO:B0065065 name: EMSY_HUMAN-Phosphoserine1130 def: "Protein EMSY_HUMAN with the residue 1130 substituted with Phosphoserine" [UniProtKB:Q7Z589] xref: UniProtKB:Q7Z589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057175 ! EMSY_HUMAN [Term] id: CCO:B0065066 name: EMSY_HUMAN-Phosphoserine1136 def: "Protein EMSY_HUMAN with the residue 1136 substituted with Phosphoserine" [UniProtKB:Q7Z589] xref: UniProtKB:Q7Z589 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057175 ! EMSY_HUMAN [Term] id: CCO:B0065067 name: ENL_HUMAN-Phosphoserine155 def: "Protein ENL_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q03111] xref: UniProtKB:Q03111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055720 ! ENL_HUMAN [Term] id: CCO:B0065068 name: ENL_HUMAN-Phosphoserine209 def: "Protein ENL_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q03111] xref: UniProtKB:Q03111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055720 ! ENL_HUMAN [Term] id: CCO:B0065069 name: ENL_HUMAN-Phosphoserine292 def: "Protein ENL_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q03111] xref: UniProtKB:Q03111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055720 ! ENL_HUMAN [Term] id: CCO:B0065070 name: ENL_HUMAN-Phosphoserine359 def: "Protein ENL_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:Q03111] xref: UniProtKB:Q03111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055720 ! ENL_HUMAN [Term] id: CCO:B0065071 name: ENL_HUMAN-Phosphoserine361 def: "Protein ENL_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q03111] xref: UniProtKB:Q03111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055720 ! ENL_HUMAN [Term] id: CCO:B0065072 name: ENL_HUMAN-Phosphoserine366 def: "Protein ENL_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q03111] xref: UniProtKB:Q03111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055720 ! ENL_HUMAN [Term] id: CCO:B0065073 name: ENL_HUMAN-Phosphoserine475 def: "Protein ENL_HUMAN with the residue 475 substituted with Phosphoserine" [UniProtKB:Q03111] xref: UniProtKB:Q03111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055720 ! ENL_HUMAN [Term] id: CCO:B0065074 name: ENPL_HUMAN-Phosphoserine306 def: "Protein ENPL_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:P14625] comment: By similarity xref: UniProtKB:P14625 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055025 ! ENPL_HUMAN [Term] id: CCO:B0065075 name: ENPL_HUMAN-Phosphotyrosine677 def: "Protein ENPL_HUMAN with the residue 677 substituted with Phosphotyrosine" [UniProtKB:P14625] xref: UniProtKB:P14625 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055025 ! ENPL_HUMAN [Term] id: CCO:B0065076 name: EP15_HUMAN-Phosphoserine140 def: "Protein EP15_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P42566] xref: UniProtKB:P42566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:B0065077 name: EP400_HUMAN-Phosphothreonine314 def: "Protein EP400_HUMAN with the residue 314 substituted with Phosphothreonine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065078 name: EP400_HUMAN-Phosphoserine315 def: "Protein EP400_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065079 name: EP400_HUMAN-Phosphothreonine320 def: "Protein EP400_HUMAN with the residue 320 substituted with Phosphothreonine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065080 name: EP400_HUMAN-Phosphoserine941 def: "Protein EP400_HUMAN with the residue 941 substituted with Phosphoserine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065081 name: EP400_HUMAN-Phosphoserine943 def: "Protein EP400_HUMAN with the residue 943 substituted with Phosphoserine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065082 name: EP400_HUMAN-Phosphothreonine945 def: "Protein EP400_HUMAN with the residue 945 substituted with Phosphothreonine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065083 name: EP400_HUMAN-Phosphoserine1728 def: "Protein EP400_HUMAN with the residue 1728 substituted with Phosphoserine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065084 name: EP400_HUMAN-Phosphoserine1732 def: "Protein EP400_HUMAN with the residue 1732 substituted with Phosphoserine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065085 name: EP400_HUMAN-Phosphothreonine2814 def: "Protein EP400_HUMAN with the residue 2814 substituted with Phosphothreonine" [UniProtKB:Q96L91] xref: UniProtKB:Q96L91 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005916 ! EP400_HUMAN [Term] id: CCO:B0065086 name: EPB42_HUMAN-Phosphoserine248 def: "Protein EPB42_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:P16452] comment: by PKA; Probable xref: UniProtKB:P16452 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055051 ! EPB42_HUMAN [Term] id: CCO:B0065087 name: EPHA2_HUMAN-Phosphotyrosine575 def: "Protein EPHA2_HUMAN with the residue 575 substituted with Phosphotyrosine" [UniProtKB:P29317] xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0065088 name: EPHA2_HUMAN-Phosphoserine892 def: "Protein EPHA2_HUMAN with the residue 892 substituted with Phosphoserine" [UniProtKB:P29317] xref: UniProtKB:P29317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005832 ! EPHA2_HUMAN [Term] id: CCO:B0065089 name: EPHB3_HUMAN-Phosphotyrosine600 def: "Protein EPHB3_HUMAN with the residue 600 substituted with Phosphotyrosine" [UniProtKB:P54753] xref: UniProtKB:P54753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001340 ! ephrin receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001690 ! axon guidance receptor activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0014968 ! EPHB3_HUMAN [Term] id: CCO:B0065090 name: EPHB4_HUMAN-Phosphothreonine976 def: "Protein EPHB4_HUMAN with the residue 976 substituted with Phosphothreonine" [UniProtKB:P54760] xref: UniProtKB:P54760 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005833 ! EPHB4_HUMAN [Term] id: CCO:B0065091 name: EPOR_HUMAN-Phosphotyrosine368 def: "Protein EPOR_HUMAN with the residue 368 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065092 name: EPOR_HUMAN-Phosphotyrosine426 def: "Protein EPOR_HUMAN with the residue 426 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065093 name: EPOR_HUMAN-Phosphotyrosine454 def: "Protein EPOR_HUMAN with the residue 454 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065094 name: EPOR_HUMAN-Phosphotyrosine456 def: "Protein EPOR_HUMAN with the residue 456 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065095 name: EPOR_HUMAN-Phosphotyrosine468 def: "Protein EPOR_HUMAN with the residue 468 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065096 name: EPOR_HUMAN-Phosphotyrosine485 def: "Protein EPOR_HUMAN with the residue 485 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065097 name: EPOR_HUMAN-Phosphotyrosine489 def: "Protein EPOR_HUMAN with the residue 489 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065098 name: EPOR_HUMAN-Phosphotyrosine504 def: "Protein EPOR_HUMAN with the residue 504 substituted with Phosphotyrosine" [UniProtKB:P19235] comment: by JAK2; By similarity xref: UniProtKB:P19235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001247 ! erythropoietin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:B0065099 name: EPS8_HUMAN-Phosphotyrosine525 def: "Protein EPS8_HUMAN with the residue 525 substituted with Phosphotyrosine" [UniProtKB:Q12929] xref: UniProtKB:Q12929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019772 ! EPS8_HUMAN [Term] id: CCO:B0065100 name: EPS8_HUMAN-Phosphotyrosine774 def: "Protein EPS8_HUMAN with the residue 774 substituted with Phosphotyrosine" [UniProtKB:Q12929] xref: UniProtKB:Q12929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019772 ! EPS8_HUMAN [Term] id: CCO:B0065101 name: EPS8_HUMAN-Phosphoserine811 def: "Protein EPS8_HUMAN with the residue 811 substituted with Phosphoserine" [UniProtKB:Q12929] xref: UniProtKB:Q12929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019772 ! EPS8_HUMAN [Term] id: CCO:B0065102 name: EPS8_HUMAN-Phosphoserine815 def: "Protein EPS8_HUMAN with the residue 815 substituted with Phosphoserine" [UniProtKB:Q12929] xref: UniProtKB:Q12929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019772 ! EPS8_HUMAN [Term] id: CCO:B0065103 name: ERBB2_HUMAN-Phosphotyrosine735 def: "Protein ERBB2_HUMAN with the residue 735 substituted with Phosphotyrosine" [UniProtKB:P04626] xref: UniProtKB:P04626 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001343 ! epidermal growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005796 ! ErbB-3 class receptor binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001751 ! receptor complex relationship: transformation_of CCO:B0005540 ! ERBB2_HUMAN [Term] id: CCO:B0065104 name: ERBB4_HUMAN-Phosphotyrosine733 def: "Protein ERBB4_HUMAN with the residue 733 substituted with Phosphotyrosine" [UniProtKB:Q15303] xref: UniProtKB:Q15303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:B0065105 name: ERC6L_HUMAN-Phosphoserine14 def: "Protein ERC6L_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065106 name: ERC6L_HUMAN-Phosphoserine774 def: "Protein ERC6L_HUMAN with the residue 774 substituted with Phosphoserine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065107 name: ERC6L_HUMAN-Phosphoserine807 def: "Protein ERC6L_HUMAN with the residue 807 substituted with Phosphoserine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065108 name: ERC6L_HUMAN-Phosphoserine810 def: "Protein ERC6L_HUMAN with the residue 810 substituted with Phosphoserine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065109 name: ERC6L_HUMAN-Phosphothreonine813 def: "Protein ERC6L_HUMAN with the residue 813 substituted with Phosphothreonine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065110 name: ERC6L_HUMAN-Phosphoserine820 def: "Protein ERC6L_HUMAN with the residue 820 substituted with Phosphoserine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065111 name: ERC6L_HUMAN-Phosphoserine1028 def: "Protein ERC6L_HUMAN with the residue 1028 substituted with Phosphoserine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065112 name: ERC6L_HUMAN-Phosphoserine1069 def: "Protein ERC6L_HUMAN with the residue 1069 substituted with Phosphoserine" [UniProtKB:Q2NKX8] xref: UniProtKB:Q2NKX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041256 ! ERC6L_HUMAN [Term] id: CCO:B0065113 name: ERCC6_HUMAN-Phosphoserine158 def: "Protein ERCC6_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065114 name: ERCC6_HUMAN-Phosphoserine429 def: "Protein ERCC6_HUMAN with the residue 429 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065115 name: ERCC6_HUMAN-Phosphoserine430 def: "Protein ERCC6_HUMAN with the residue 430 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065116 name: ERCC6_HUMAN-Phosphoserine486 def: "Protein ERCC6_HUMAN with the residue 486 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065117 name: ERCC6_HUMAN-Phosphoserine489 def: "Protein ERCC6_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065118 name: ERCC6_HUMAN-Phosphoserine1142 def: "Protein ERCC6_HUMAN with the residue 1142 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065119 name: ERCC6_HUMAN-Phosphoserine1348 def: "Protein ERCC6_HUMAN with the residue 1348 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065120 name: ERCC6_HUMAN-Phosphoserine1461 def: "Protein ERCC6_HUMAN with the residue 1461 substituted with Phosphoserine" [UniProtKB:Q03468] xref: UniProtKB:Q03468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:B0065121 name: ERF1_HUMAN-N-acetylalanine2 def: "Protein ERF1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62495] xref: UniProtKB:P62495 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000318 ! translation release factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001699 ! translation termination factor activity relationship: has_function CCO:F0003040 ! translation release factor activity, codon specific relationship: has_function CCO:F0005784 ! ribosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055619 ! ERF1_HUMAN [Term] id: CCO:B0065122 name: ERF_HUMAN-Phosphothreonine3 def: "Protein ERF_HUMAN with the residue 3 substituted with Phosphothreonine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065123 name: ERF_HUMAN-Phosphothreonine7 def: "Protein ERF_HUMAN with the residue 7 substituted with Phosphothreonine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065124 name: ERF_HUMAN-Phosphotyrosine16 def: "Protein ERF_HUMAN with the residue 16 substituted with Phosphotyrosine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065125 name: ERF_HUMAN-Phosphoserine20 def: "Protein ERF_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065126 name: ERF_HUMAN-Phosphothreonine148 def: "Protein ERF_HUMAN with the residue 148 substituted with Phosphothreonine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065127 name: ERF_HUMAN-Phosphoserine171 def: "Protein ERF_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065128 name: ERF_HUMAN-Phosphoserine327 def: "Protein ERF_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065129 name: ERF_HUMAN-Phosphoserine431 def: "Protein ERF_HUMAN with the residue 431 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065130 name: ERF_HUMAN-Phosphoserine435 def: "Protein ERF_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065131 name: ERF_HUMAN-Phosphothreonine441 def: "Protein ERF_HUMAN with the residue 441 substituted with Phosphothreonine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000294 ! ligand-regulated transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065132 name: ERF_HUMAN-Phosphoserine444 def: "Protein ERF_HUMAN with the residue 444 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065133 name: ERF_HUMAN-Phosphoserine548 def: "Protein ERF_HUMAN with the residue 548 substituted with Phosphoserine" [UniProtKB:P50548] xref: UniProtKB:P50548 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001642 ! ERF_HUMAN [Term] id: CCO:B0065134 name: ERG_HUMAN-Phosphoserine93 def: "Protein ERG_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:P11308] xref: UniProtKB:P11308 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054991 ! ERG_HUMAN [Term] id: CCO:B0065135 name: ERR1_HUMAN-Phosphoserine19 def: "Protein ERR1_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:P11474] comment: By similarity xref: UniProtKB:P11474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038838 ! ERR1_HUMAN [Term] id: CCO:B0065136 name: ERR1_HUMAN-Phosphoserine22 def: "Protein ERR1_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:P11474] xref: UniProtKB:P11474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038838 ! ERR1_HUMAN [Term] id: CCO:B0065137 name: ERR1_HUMAN-Phosphoserine27 def: "Protein ERR1_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P11474] xref: UniProtKB:P11474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0038838 ! ERR1_HUMAN [Term] id: CCO:B0065138 name: ESCO1_HUMAN-Phosphoserine200 def: "Protein ESCO1_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q5FWF5] xref: UniProtKB:Q5FWF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001848 ! ESCO1_HUMAN [Term] id: CCO:B0065139 name: ESCO2_HUMAN-Phosphoserine75 def: "Protein ESCO2_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q56NI9] xref: UniProtKB:Q56NI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001841 ! ESCO2_HUMAN [Term] id: CCO:B0065140 name: ESCO2_HUMAN-Phosphoserine244 def: "Protein ESCO2_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:Q56NI9] xref: UniProtKB:Q56NI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001841 ! ESCO2_HUMAN [Term] id: CCO:B0065141 name: ESF1_HUMAN-Phosphoserine75 def: "Protein ESF1_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065142 name: ESF1_HUMAN-Phosphoserine77 def: "Protein ESF1_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065143 name: ESF1_HUMAN-Phosphoserine79 def: "Protein ESF1_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065144 name: ESF1_HUMAN-Phosphoserine82 def: "Protein ESF1_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065145 name: ESF1_HUMAN-Phosphoserine90 def: "Protein ESF1_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065146 name: ESF1_HUMAN-Phosphoserine153 def: "Protein ESF1_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065147 name: ESF1_HUMAN-Phosphoserine179 def: "Protein ESF1_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065148 name: ESF1_HUMAN-Phosphoserine180 def: "Protein ESF1_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065149 name: ESF1_HUMAN-Phosphoserine198 def: "Protein ESF1_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065150 name: ESF1_HUMAN-Phosphoserine296 def: "Protein ESF1_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065151 name: ESF1_HUMAN-Phosphoserine298 def: "Protein ESF1_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065152 name: ESF1_HUMAN-Phosphothreonine311 def: "Protein ESF1_HUMAN with the residue 311 substituted with Phosphothreonine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065153 name: ESF1_HUMAN-Phosphoserine312 def: "Protein ESF1_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065154 name: ESF1_HUMAN-Phosphoserine313 def: "Protein ESF1_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065155 name: ESF1_HUMAN-Phosphoserine657 def: "Protein ESF1_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065156 name: ESF1_HUMAN-Phosphoserine663 def: "Protein ESF1_HUMAN with the residue 663 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065157 name: ESF1_HUMAN-Phosphothreonine693 def: "Protein ESF1_HUMAN with the residue 693 substituted with Phosphothreonine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065158 name: ESF1_HUMAN-Phosphoserine694 def: "Protein ESF1_HUMAN with the residue 694 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065159 name: ESF1_HUMAN-Phosphoserine735 def: "Protein ESF1_HUMAN with the residue 735 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065160 name: ESF1_HUMAN-Phosphoserine823 def: "Protein ESF1_HUMAN with the residue 823 substituted with Phosphoserine" [UniProtKB:Q9H501] xref: UniProtKB:Q9H501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058722 ! ESF1_HUMAN [Term] id: CCO:B0065161 name: ESPL1_HUMAN-Phosphoserine1396 def: "Protein ESPL1_HUMAN with the residue 1396 substituted with Phosphoserine" [UniProtKB:Q14674] xref: UniProtKB:Q14674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001787 ! ESPL1_HUMAN [Term] id: CCO:B0065162 name: ESPL1_HUMAN-Phosphoserine1399 def: "Protein ESPL1_HUMAN with the residue 1399 substituted with Phosphoserine" [UniProtKB:Q14674] xref: UniProtKB:Q14674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001787 ! ESPL1_HUMAN [Term] id: CCO:B0065163 name: ESR2_HUMAN-Phosphoserine87 def: "Protein ESR2_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q92731] comment: By similarity xref: UniProtKB:Q92731 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0004376 ! estrogen receptor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007301 ! receptor antagonist activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0058084 ! ESR2_HUMAN [Term] id: CCO:B0065164 name: ESR2_HUMAN-Phosphotyrosine488 def: "Protein ESR2_HUMAN with the residue 488 substituted with Phosphotyrosine" [UniProtKB:Q92731] comment: By similarity xref: UniProtKB:Q92731 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058084 ! ESR2_HUMAN [Term] id: CCO:B0065165 name: ETBR2_HUMAN-Phosphoserine471 def: "Protein ETBR2_HUMAN with the residue 471 substituted with Phosphoserine" [UniProtKB:O60883] comment: By similarity xref: UniProtKB:O60883 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054585 ! ETBR2_HUMAN [Term] id: CCO:B0065166 name: ETS1_HUMAN-Phosphothreonine38 def: "Protein ETS1_HUMAN with the residue 38 substituted with Phosphothreonine" [UniProtKB:P14921] comment: by MAPK; By similarity xref: UniProtKB:P14921 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030313 ! ETS1_HUMAN [Term] id: CCO:B0065167 name: ETS1_HUMAN-Phosphotyrosine205 def: "Protein ETS1_HUMAN with the residue 205 substituted with Phosphotyrosine" [UniProtKB:P14921] xref: UniProtKB:P14921 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030313 ! ETS1_HUMAN [Term] id: CCO:B0065168 name: ETS1_HUMAN-Phosphotyrosine223 def: "Protein ETS1_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:P14921] xref: UniProtKB:P14921 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030313 ! ETS1_HUMAN [Term] id: CCO:B0065169 name: ETV4_HUMAN-Phosphoserine140 def: "Protein ETV4_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:P43268] xref: UniProtKB:P43268 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055362 ! ETV4_HUMAN [Term] id: CCO:B0065170 name: ETV4_HUMAN-Phosphoserine149 def: "Protein ETV4_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:P43268] xref: UniProtKB:P43268 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055362 ! ETV4_HUMAN [Term] id: CCO:B0065171 name: ETV6_HUMAN-Phosphothreonine18 def: "Protein ETV6_HUMAN with the residue 18 substituted with Phosphothreonine" [UniProtKB:P41212] xref: UniProtKB:P41212 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028354 ! ETV6_HUMAN [Term] id: CCO:B0065172 name: EVL_HUMAN-Phosphoserine246 def: "Protein EVL_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065173 name: EVL_HUMAN-Phosphothreonine250 def: "Protein EVL_HUMAN with the residue 250 substituted with Phosphothreonine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065174 name: EVL_HUMAN-Phosphoserine304 def: "Protein EVL_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065175 name: EVL_HUMAN-Phosphoserine306 def: "Protein EVL_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001653 ! profilin binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065176 name: EVL_HUMAN-Phosphoserine329 def: "Protein EVL_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065177 name: EVL_HUMAN-Phosphoserine331 def: "Protein EVL_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065178 name: EVL_HUMAN-Phosphoserine345 def: "Protein EVL_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065179 name: EVL_HUMAN-Phosphoserine349 def: "Protein EVL_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q9UI08] xref: UniProtKB:Q9UI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:B0065180 name: EXO1_HUMAN-Phosphoserine422 def: "Protein EXO1_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q9UQ84] xref: UniProtKB:Q9UQ84 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002240 ! EXO1_HUMAN [Term] id: CCO:B0065181 name: EXOC1_HUMAN-Phosphoserine470 def: "Protein EXOC1_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:Q9NV70] xref: UniProtKB:Q9NV70 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000024 ! exocyst relationship: transformation_of CCO:B0005592 ! EXOC1_HUMAN [Term] id: CCO:B0065182 name: EXOC1_HUMAN-Phosphoserine473 def: "Protein EXOC1_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:Q9NV70] xref: UniProtKB:Q9NV70 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005592 ! EXOC1_HUMAN [Term] id: CCO:B0065183 name: EXOC8_HUMAN-Phosphothreonine142 def: "Protein EXOC8_HUMAN with the residue 142 substituted with Phosphothreonine" [UniProtKB:Q8IYI6] xref: UniProtKB:Q8IYI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005255 ! EXOC8_HUMAN [Term] id: CCO:B0065184 name: EXOS2_HUMAN-Phosphoserine124 def: "Protein EXOS2_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q13868] xref: UniProtKB:Q13868 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039757 ! EXOS2_HUMAN [Term] id: CCO:B0065185 name: EYA3_HUMAN-Phosphoserine266 def: "Protein EYA3_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q99504] xref: UniProtKB:Q99504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058420 ! EYA3_HUMAN [Term] id: CCO:B0065186 name: EYA4_HUMAN-Phosphoserine361 def: "Protein EYA4_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:O95677] xref: UniProtKB:O95677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054782 ! EYA4_HUMAN [Term] id: CCO:B0065187 name: EZH2_HUMAN-Phosphothreonine339 def: "Protein EZH2_HUMAN with the residue 339 substituted with Phosphothreonine" [UniProtKB:Q15910] xref: UniProtKB:Q15910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:B0065188 name: EZH2_HUMAN-Phosphoserine366 def: "Protein EZH2_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q15910] xref: UniProtKB:Q15910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:B0065189 name: EZH2_HUMAN-Phosphothreonine367 def: "Protein EZH2_HUMAN with the residue 367 substituted with Phosphothreonine" [UniProtKB:Q15910] xref: UniProtKB:Q15910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:B0065190 name: FABP6_HUMAN-N-acetylalanine2 def: "Protein FABP6_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P51161] comment: By similarity xref: UniProtKB:P51161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055461 ! FABP6_HUMAN [Term] id: CCO:B0065191 name: FADD_HUMAN-Phosphoserine194 def: "Protein FADD_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q13158] comment: Probable xref: UniProtKB:Q13158 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001425 ! death receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:B0065192 name: FAF1_HUMAN-Phosphotyrosine225 def: "Protein FAF1_HUMAN with the residue 225 substituted with Phosphotyrosine" [UniProtKB:Q9UNN5] xref: UniProtKB:Q9UNN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059254 ! FAF1_HUMAN [Term] id: CCO:B0065193 name: 1433G_HUMAN-N-acetylmethionine1 def: "Protein 1433G_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P61981] comment: alternate; xref: UniProtKB:P61981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005489 ! 1433G_HUMAN [Term] id: CCO:B0065194 name: 2A5A_HUMAN-Phosphoserine41 def: "Protein 2A5A_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q15172] xref: UniProtKB:Q15172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:B0065195 name: 2A5A_HUMAN-Phosphoserine42 def: "Protein 2A5A_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q15172] xref: UniProtKB:Q15172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:B0065196 name: 2A5D_HUMAN-Phosphoserine573 def: "Protein 2A5D_HUMAN with the residue 573 substituted with Phosphoserine" [UniProtKB:Q14738] xref: UniProtKB:Q14738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002006 ! protein phosphatase type 2A regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000029 ! protein phosphatase type 2A complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005515 ! 2A5D_HUMAN [Term] id: CCO:B0065197 name: 3BP2_HUMAN-Phosphoserine278 def: "Protein 3BP2_HUMAN with the residue 278 substituted with Phosphoserine" [UniProtKB:P78314] xref: UniProtKB:P78314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055636 ! 3BP2_HUMAN [Term] id: CCO:B0065198 name: 3BP5_HUMAN-Phosphoserine351 def: "Protein 3BP5_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:O60239] comment: by MAPK12 and MAPK9; By similarity xref: UniProtKB:O60239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017622 ! 3BP5_HUMAN [Term] id: CCO:B0065199 name: 3BP5_HUMAN-Phosphoserine418 def: "Protein 3BP5_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:O60239] comment: By similarity xref: UniProtKB:O60239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017622 ! 3BP5_HUMAN [Term] id: CCO:B0065200 name: 3BP5_HUMAN-Phosphoserine421 def: "Protein 3BP5_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:O60239] comment: by MAPK12; By similarity xref: UniProtKB:O60239 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017622 ! 3BP5_HUMAN [Term] id: CCO:B0065201 name: 4EBP1_HUMAN-N-acetylserine2 def: "Protein 4EBP1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065202 name: 4EBP1_HUMAN-Phosphoserine35 def: "Protein 4EBP1_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065203 name: 4EBP1_HUMAN-Phosphothreonine36 def: "Protein 4EBP1_HUMAN with the residue 36 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065204 name: 4EBP1_HUMAN-Phosphothreonine37 def: "Protein 4EBP1_HUMAN with the residue 37 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065205 name: 4EBP1_HUMAN-Phosphothreonine41 def: "Protein 4EBP1_HUMAN with the residue 41 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065206 name: 4EBP1_HUMAN-Phosphothreonine46 def: "Protein 4EBP1_HUMAN with the residue 46 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065207 name: 4EBP1_HUMAN-Phosphothreonine50 def: "Protein 4EBP1_HUMAN with the residue 50 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065208 name: 4EBP1_HUMAN-Phosphotyrosine54 def: "Protein 4EBP1_HUMAN with the residue 54 substituted with Phosphotyrosine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001770 ! eukaryotic initiation factor 4E binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065209 name: 4EBP1_HUMAN-Phosphoserine65 def: "Protein 4EBP1_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q13541] comment: by MAPK1 and MAPK3; xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065210 name: 4EBP1_HUMAN-Phosphothreonine68 def: "Protein 4EBP1_HUMAN with the residue 68 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065211 name: 4EBP1_HUMAN-Phosphothreonine70 def: "Protein 4EBP1_HUMAN with the residue 70 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065212 name: 4EBP1_HUMAN-Phosphothreonine77 def: "Protein 4EBP1_HUMAN with the residue 77 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065213 name: 4EBP1_HUMAN-Phosphothreonine82 def: "Protein 4EBP1_HUMAN with the residue 82 substituted with Phosphothreonine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065214 name: 4EBP1_HUMAN-Phosphoserine83 def: "Protein 4EBP1_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065215 name: 4EBP1_HUMAN-Phosphoserine94 def: "Protein 4EBP1_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065216 name: 4EBP1_HUMAN-Phosphoserine101 def: "Protein 4EBP1_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065217 name: 4EBP1_HUMAN-Phosphoserine112 def: "Protein 4EBP1_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:Q13541] xref: UniProtKB:Q13541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:B0065218 name: 4EBP2_HUMAN-Phosphothreonine37 def: "Protein 4EBP2_HUMAN with the residue 37 substituted with Phosphothreonine" [UniProtKB:Q13542] xref: UniProtKB:Q13542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055928 ! 4EBP2_HUMAN [Term] id: CCO:B0065219 name: 4EBP2_HUMAN-Phosphothreonine46 def: "Protein 4EBP2_HUMAN with the residue 46 substituted with Phosphothreonine" [UniProtKB:Q13542] xref: UniProtKB:Q13542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001770 ! eukaryotic initiation factor 4E binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055928 ! 4EBP2_HUMAN [Term] id: CCO:B0065220 name: 4EBP2_HUMAN-Phosphoserine65 def: "Protein 4EBP2_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q13542] comment: by MAPK1 and MAPK3; By similarity xref: UniProtKB:Q13542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055928 ! 4EBP2_HUMAN [Term] id: CCO:B0065221 name: 4ET_HUMAN-Phosphoserine120 def: "Protein 4ET_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0065222 name: 4ET_HUMAN-Phosphoserine136 def: "Protein 4ET_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0065223 name: 4ET_HUMAN-Phosphoserine138 def: "Protein 4ET_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0065224 name: 4ET_HUMAN-Phosphoserine345 def: "Protein 4ET_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0065225 name: 4ET_HUMAN-Phosphoserine564 def: "Protein 4ET_HUMAN with the residue 564 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0065226 name: 4ET_HUMAN-Phosphoserine951 def: "Protein 4ET_HUMAN with the residue 951 substituted with Phosphoserine" [UniProtKB:Q9NRA8] xref: UniProtKB:Q9NRA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:B0065227 name: 5HT6R_HUMAN-Phosphotyrosine125 def: "Protein 5HT6R_HUMAN with the residue 125 substituted with Phosphotyrosine" [UniProtKB:P50406] xref: UniProtKB:P50406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:B0065228 name: A4_HUMAN-Phosphotyrosine762 def: "Protein A4_HUMAN with the residue 762 substituted with Phosphotyrosine" [UniProtKB:P05067] xref: UniProtKB:P05067 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005474 ! A4_HUMAN [Term] id: CCO:B0065229 name: AA3R_HUMAN-Phosphoserine317 def: "Protein AA3R_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:P33765] comment: By similarity xref: UniProtKB:P33765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000164 ! adenosine receptor activity, G-protein coupled relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055269 ! AA3R_HUMAN [Term] id: CCO:B0065230 name: AAAT_HUMAN-Phosphoserine535 def: "Protein AAAT_HUMAN with the residue 535 substituted with Phosphoserine" [UniProtKB:Q15758] xref: UniProtKB:Q15758 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002648 ! amino acid transmembrane transporter activity relationship: has_function CCO:F0002652 ! neutral amino acid transmembrane transporter activity relationship: has_function CCO:F0002742 ! symporter activity relationship: has_function CCO:F0003597 ! sodium:dicarboxylate symporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0063082 ! AAAT_HUMAN [Term] id: CCO:B0065231 name: AAKB1_HUMAN-Phosphothreonine4 def: "Protein AAKB1_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:Q9Y478] xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065232 name: AAKB1_HUMAN-Phosphoserine5 def: "Protein AAKB1_HUMAN with the residue 5 substituted with Phosphoserine" [UniProtKB:Q9Y478] xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065233 name: AAKB1_HUMAN-Phosphoserine6 def: "Protein AAKB1_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q9Y478] xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065234 name: AAKB1_HUMAN-Phosphoserine24 def: "Protein AAKB1_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q9Y478] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065235 name: AAKB1_HUMAN-Phosphoserine25 def: "Protein AAKB1_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q9Y478] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065236 name: AAKB1_HUMAN-Phosphoserine96 def: "Protein AAKB1_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q9Y478] comment: By similarity xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065237 name: AAKB1_HUMAN-Phosphoserine101 def: "Protein AAKB1_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q9Y478] comment: By similarity xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065238 name: AAKB1_HUMAN-Phosphoserine108 def: "Protein AAKB1_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q9Y478] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065239 name: AAKB1_HUMAN-Phosphoserine182 def: "Protein AAKB1_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q9Y478] comment: By similarity xref: UniProtKB:Q9Y478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:B0065240 name: AAKB2_HUMAN-Phosphoserine108 def: "Protein AAKB2_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:O43741] xref: UniProtKB:O43741 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054517 ! AAKB2_HUMAN [Term] id: CCO:B0065241 name: AAKB2_HUMAN-Phosphoserine183 def: "Protein AAKB2_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:O43741] comment: By similarity xref: UniProtKB:O43741 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: located_in CCO:C0001298 ! AMP-activated protein kinase complex relationship: transformation_of CCO:B0054517 ! AAKB2_HUMAN [Term] id: CCO:B0065242 name: AAKG2_HUMAN-Phosphoserine65 def: "Protein AAKG2_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] comment: By similarity xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065243 name: AAKG2_HUMAN-Phosphoserine71 def: "Protein AAKG2_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] comment: By similarity xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065244 name: AAKG2_HUMAN-Phosphoserine73 def: "Protein AAKG2_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] comment: By similarity xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065245 name: AAKG2_HUMAN-Phosphoserine90 def: "Protein AAKG2_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] comment: By similarity xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065246 name: AAKG2_HUMAN-Phosphoserine138 def: "Protein AAKG2_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] comment: By similarity xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065247 name: AAKG2_HUMAN-Phosphoserine157 def: "Protein AAKG2_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065248 name: AAKG2_HUMAN-Phosphoserine161 def: "Protein AAKG2_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] comment: By similarity xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065249 name: AAKG2_HUMAN-Phosphoserine162 def: "Protein AAKG2_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065250 name: AAKG2_HUMAN-Phosphothreonine167 def: "Protein AAKG2_HUMAN with the residue 167 substituted with Phosphothreonine" [UniProtKB:Q9UGJ0] xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065251 name: AAKG2_HUMAN-Phosphoserine196 def: "Protein AAKG2_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:Q9UGJ0] comment: By similarity xref: UniProtKB:Q9UGJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016326 ! AAKG2_HUMAN [Term] id: CCO:B0065252 name: AAPK1_HUMAN-Phosphothreonine260 def: "Protein AAPK1_HUMAN with the residue 260 substituted with Phosphothreonine" [UniProtKB:Q13131] comment: By similarity xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0065253 name: AAPK1_HUMAN-Phosphoserine347 def: "Protein AAPK1_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q13131] xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0065254 name: AAPK1_HUMAN-Phosphotyrosine433 def: "Protein AAPK1_HUMAN with the residue 433 substituted with Phosphotyrosine" [UniProtKB:Q13131] xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0065255 name: AAPK1_HUMAN-Phosphoserine477 def: "Protein AAPK1_HUMAN with the residue 477 substituted with Phosphoserine" [UniProtKB:Q13131] xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0065256 name: AAPK1_HUMAN-Phosphothreonine481 def: "Protein AAPK1_HUMAN with the residue 481 substituted with Phosphothreonine" [UniProtKB:Q13131] xref: UniProtKB:Q13131 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:B0065257 name: AAPK2_HUMAN-Phosphothreonine172 def: "Protein AAPK2_HUMAN with the residue 172 substituted with Phosphothreonine" [UniProtKB:P54646] comment: by STK11; By similarity xref: UniProtKB:P54646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055514 ! AAPK2_HUMAN [Term] id: CCO:B0065258 name: AAPK2_HUMAN-Phosphoserine173 def: "Protein AAPK2_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:P54646] xref: UniProtKB:P54646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055514 ! AAPK2_HUMAN [Term] id: CCO:B0065259 name: AAPK2_HUMAN-Phosphoserine176 def: "Protein AAPK2_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:P54646] xref: UniProtKB:P54646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055514 ! AAPK2_HUMAN [Term] id: CCO:B0065260 name: AAPK2_HUMAN-Phosphothreonine258 def: "Protein AAPK2_HUMAN with the residue 258 substituted with Phosphothreonine" [UniProtKB:P54646] comment: By similarity xref: UniProtKB:P54646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055514 ! AAPK2_HUMAN [Term] id: CCO:B0065261 name: AAPK2_HUMAN-Phosphoserine377 def: "Protein AAPK2_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:P54646] xref: UniProtKB:P54646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055514 ! AAPK2_HUMAN [Term] id: CCO:B0065262 name: AAPK2_HUMAN-Phosphoserine491 def: "Protein AAPK2_HUMAN with the residue 491 substituted with Phosphoserine" [UniProtKB:P54646] comment: By similarity xref: UniProtKB:P54646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055514 ! AAPK2_HUMAN [Term] id: CCO:B0065263 name: AAPK2_HUMAN-Phosphoserine500 def: "Protein AAPK2_HUMAN with the residue 500 substituted with Phosphoserine" [UniProtKB:P54646] comment: By similarity xref: UniProtKB:P54646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055514 ! AAPK2_HUMAN [Term] id: CCO:B0065264 name: AB1IP_HUMAN-Phosphoserine531 def: "Protein AB1IP_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:Q7Z5R6] comment: By similarity xref: UniProtKB:Q7Z5R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028914 ! AB1IP_HUMAN [Term] id: CCO:B0065265 name: ABCA2_HUMAN-Phosphoserine1327 def: "Protein ABCA2_HUMAN with the residue 1327 substituted with Phosphoserine" [UniProtKB:Q9BZC7] xref: UniProtKB:Q9BZC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058595 ! ABCA2_HUMAN [Term] id: CCO:B0065266 name: ABCA2_HUMAN-Phosphoserine1331 def: "Protein ABCA2_HUMAN with the residue 1331 substituted with Phosphoserine" [UniProtKB:Q9BZC7] xref: UniProtKB:Q9BZC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001725 ! ATP-binding cassette (ABC) transporter complex relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: transformation_of CCO:B0058595 ! ABCA2_HUMAN [Term] id: CCO:B0065267 name: ABCA2_HUMAN-Phosphothreonine2412 def: "Protein ABCA2_HUMAN with the residue 2412 substituted with Phosphothreonine" [UniProtKB:Q9BZC7] xref: UniProtKB:Q9BZC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058595 ! ABCA2_HUMAN [Term] id: CCO:B0065268 name: ABCF1_HUMAN-Phosphoserine24 def: "Protein ABCF1_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065269 name: ABCF1_HUMAN-Phosphoserine105 def: "Protein ABCF1_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065270 name: ABCF1_HUMAN-Phosphothreonine108 def: "Protein ABCF1_HUMAN with the residue 108 substituted with Phosphothreonine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065271 name: ABCF1_HUMAN-Phosphoserine109 def: "Protein ABCF1_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065272 name: ABCF1_HUMAN-Phosphoserine140 def: "Protein ABCF1_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065273 name: ABCF1_HUMAN-Phosphoserine166 def: "Protein ABCF1_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065274 name: ABCF1_HUMAN-Phosphoserine228 def: "Protein ABCF1_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065275 name: ABCF1_HUMAN-Phosphoserine595 def: "Protein ABCF1_HUMAN with the residue 595 substituted with Phosphoserine" [UniProtKB:Q8NE71] xref: UniProtKB:Q8NE71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:B0065276 name: ABI1_HUMAN-Phosphoserine216 def: "Protein ABI1_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q8IZP0] xref: UniProtKB:Q8IZP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:B0065277 name: ABI2_HUMAN-Phosphoserine227 def: "Protein ABI2_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q9NYB9] xref: UniProtKB:Q9NYB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038095 ! ABI2_HUMAN [Term] id: CCO:B0065278 name: ABL2_HUMAN-Phosphoserine620 def: "Protein ABL2_HUMAN with the residue 620 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0065279 name: ABL2_HUMAN-Phosphoserine633 def: "Protein ABL2_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0065280 name: ABL2_HUMAN-Phosphoserine655 def: "Protein ABL2_HUMAN with the residue 655 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0065281 name: ABL2_HUMAN-Phosphoserine915 def: "Protein ABL2_HUMAN with the residue 915 substituted with Phosphoserine" [UniProtKB:P42684] xref: UniProtKB:P42684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:B0065282 name: ABLM1_HUMAN-Phosphoserine216 def: "Protein ABLM1_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:O14639] comment: By similarity xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065283 name: ABLM1_HUMAN-Phosphoserine353 def: "Protein ABLM1_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:O14639] comment: By similarity xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065284 name: ABLM1_HUMAN-Phosphotyrosine357 def: "Protein ABLM1_HUMAN with the residue 357 substituted with Phosphotyrosine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065285 name: ABLM1_HUMAN-Phosphoserine367 def: "Protein ABLM1_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:O14639] comment: By similarity xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065286 name: ABLM1_HUMAN-Phosphotyrosine373 def: "Protein ABLM1_HUMAN with the residue 373 substituted with Phosphotyrosine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065287 name: ABLM1_HUMAN-Phosphotyrosine396 def: "Protein ABLM1_HUMAN with the residue 396 substituted with Phosphotyrosine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065288 name: ABLM1_HUMAN-Phosphotyrosine406 def: "Protein ABLM1_HUMAN with the residue 406 substituted with Phosphotyrosine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065289 name: ABLM1_HUMAN-Phosphotyrosine410 def: "Protein ABLM1_HUMAN with the residue 410 substituted with Phosphotyrosine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065290 name: ABLM1_HUMAN-Phosphoserine431 def: "Protein ABLM1_HUMAN with the residue 431 substituted with Phosphoserine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065291 name: ABLM1_HUMAN-Phosphoserine435 def: "Protein ABLM1_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065292 name: ABLM1_HUMAN-Phosphotyrosine439 def: "Protein ABLM1_HUMAN with the residue 439 substituted with Phosphotyrosine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065293 name: ABLM1_HUMAN-Phosphoserine450 def: "Protein ABLM1_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:O14639] comment: By similarity xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065294 name: ABLM1_HUMAN-Phosphoserine452 def: "Protein ABLM1_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065295 name: ABLM1_HUMAN-Phosphoserine458 def: "Protein ABLM1_HUMAN with the residue 458 substituted with Phosphoserine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065296 name: ABLM1_HUMAN-Phosphotyrosine461 def: "Protein ABLM1_HUMAN with the residue 461 substituted with Phosphotyrosine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065297 name: ABLM1_HUMAN-Phosphoserine473 def: "Protein ABLM1_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065298 name: ABLM1_HUMAN-Phosphoserine587 def: "Protein ABLM1_HUMAN with the residue 587 substituted with Phosphoserine" [UniProtKB:O14639] comment: By similarity xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065299 name: ABLM1_HUMAN-Phosphoserine655 def: "Protein ABLM1_HUMAN with the residue 655 substituted with Phosphoserine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065300 name: ABLM1_HUMAN-Phosphoserine706 def: "Protein ABLM1_HUMAN with the residue 706 substituted with Phosphoserine" [UniProtKB:O14639] xref: UniProtKB:O14639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:B0065301 name: ABLM3_HUMAN-Phosphoserine277 def: "Protein ABLM3_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:O94929] comment: By similarity xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065302 name: ABLM3_HUMAN-Phosphoserine280 def: "Protein ABLM3_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:O94929] comment: By similarity xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065303 name: ABLM3_HUMAN-Phosphoserine282 def: "Protein ABLM3_HUMAN with the residue 282 substituted with Phosphoserine" [UniProtKB:O94929] comment: By similarity xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065304 name: ABLM3_HUMAN-Phosphoserine372 def: "Protein ABLM3_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:O94929] xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065305 name: ABLM3_HUMAN-Phosphoserine373 def: "Protein ABLM3_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:O94929] xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065306 name: ABLM3_HUMAN-Phosphoserine388 def: "Protein ABLM3_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:O94929] xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065307 name: ABLM3_HUMAN-Phosphoserine394 def: "Protein ABLM3_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:O94929] xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065308 name: ABLM3_HUMAN-Phosphoserine503 def: "Protein ABLM3_HUMAN with the residue 503 substituted with Phosphoserine" [UniProtKB:O94929] xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065309 name: ABLM3_HUMAN-Phosphoserine504 def: "Protein ABLM3_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:O94929] xref: UniProtKB:O94929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063365 ! ABLM3_HUMAN [Term] id: CCO:B0065310 name: ACACB_HUMAN-Phosphoserine220 def: "Protein ACACB_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:O00763] comment: By similarity xref: UniProtKB:O00763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054342 ! ACACB_HUMAN [Term] id: CCO:B0065311 name: ACACB_HUMAN-Phosphoserine222 def: "Protein ACACB_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:O00763] comment: By similarity xref: UniProtKB:O00763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054342 ! ACACB_HUMAN [Term] id: CCO:B0065312 name: ACCN2_HUMAN-Phosphoserine479 def: "Protein ACCN2_HUMAN with the residue 479 substituted with Phosphoserine" [UniProtKB:P78348] comment: by PKA; xref: UniProtKB:P78348 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055639 ! ACCN2_HUMAN [Term] id: CCO:B0065313 name: ACCN3_HUMAN-Phosphotyrosine375 def: "Protein ACCN3_HUMAN with the residue 375 substituted with Phosphotyrosine" [UniProtKB:Q9UHC3] xref: UniProtKB:Q9UHC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059134 ! ACCN3_HUMAN [Term] id: CCO:B0065314 name: ACCN3_HUMAN-Phosphoserine521 def: "Protein ACCN3_HUMAN with the residue 521 substituted with Phosphoserine" [UniProtKB:Q9UHC3] comment: By similarity xref: UniProtKB:Q9UHC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001524 ! cation channel activity relationship: has_function CCO:F0001527 ! sodium channel activity relationship: has_function CCO:F0002737 ! amiloride-sensitive sodium channel activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059134 ! ACCN3_HUMAN [Term] id: CCO:B0065315 name: ACE_HUMAN-Phosphothreonine716 def: "Protein ACE_HUMAN with the residue 716 substituted with Phosphothreonine" [UniProtKB:P12821] xref: UniProtKB:P12821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055006 ! ACE_HUMAN [Term] id: CCO:B0065316 name: ACE_HUMAN-Phosphoserine1299 def: "Protein ACE_HUMAN with the residue 1299 substituted with Phosphoserine" [UniProtKB:P12821] xref: UniProtKB:P12821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055006 ! ACE_HUMAN [Term] id: CCO:B0065317 name: ACHA6_HUMAN-Phosphotyrosine102 def: "Protein ACHA6_HUMAN with the residue 102 substituted with Phosphotyrosine" [UniProtKB:Q15825] xref: UniProtKB:Q15825 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0002870 ! acetylcholine receptor activity relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0032798 ! ACHA6_HUMAN [Term] id: CCO:B0065318 name: ACHB_HUMAN-Phosphotyrosine390 def: "Protein ACHB_HUMAN with the residue 390 substituted with Phosphotyrosine" [UniProtKB:P11230] comment: by Tyr-kinases; By similarity xref: UniProtKB:P11230 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054987 ! ACHB_HUMAN [Term] id: CCO:B0065319 name: ACHD_HUMAN-Phosphotyrosine390 def: "Protein ACHD_HUMAN with the residue 390 substituted with Phosphotyrosine" [UniProtKB:Q07001] comment: by Tyr-kinases; By similarity xref: UniProtKB:Q07001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001241 ! nicotinic acetylcholine-activated cation-selective channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001505 ! extracellular ligand-gated ion channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004488 ! neurotransmitter receptor activity relationship: has_function CCO:F0005634 ! acetylcholine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000449 ! nicotinic acetylcholine-gated receptor-channel complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0055779 ! ACHD_HUMAN [Term] id: CCO:B0065320 name: ACINU_HUMAN-Phosphoserine166 def: "Protein ACINU_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065321 name: ACINU_HUMAN-Phosphoserine169 def: "Protein ACINU_HUMAN with the residue 169 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065322 name: ACINU_HUMAN-Phosphoserine208 def: "Protein ACINU_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065323 name: ACINU_HUMAN-Phosphoserine216 def: "Protein ACINU_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065324 name: ACINU_HUMAN-Phosphoserine228 def: "Protein ACINU_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065325 name: ACINU_HUMAN-Phosphoserine229 def: "Protein ACINU_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065326 name: ACINU_HUMAN-Phosphoserine240 def: "Protein ACINU_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065327 name: ACINU_HUMAN-Phosphoserine243 def: "Protein ACINU_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065328 name: ACINU_HUMAN-Phosphothreonine254 def: "Protein ACINU_HUMAN with the residue 254 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065329 name: ACINU_HUMAN-Phosphoserine256 def: "Protein ACINU_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065330 name: ACINU_HUMAN-Phosphothreonine269 def: "Protein ACINU_HUMAN with the residue 269 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065331 name: ACINU_HUMAN-Phosphoserine295 def: "Protein ACINU_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065332 name: ACINU_HUMAN-Phosphoserine328 def: "Protein ACINU_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065333 name: ACINU_HUMAN-Phosphoserine365 def: "Protein ACINU_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065334 name: ACINU_HUMAN-Phosphoserine384 def: "Protein ACINU_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065335 name: ACINU_HUMAN-Phosphoserine386 def: "Protein ACINU_HUMAN with the residue 386 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065336 name: ACINU_HUMAN-Phosphoserine388 def: "Protein ACINU_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065337 name: ACINU_HUMAN-Phosphothreonine393 def: "Protein ACINU_HUMAN with the residue 393 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065338 name: ACINU_HUMAN-Phosphothreonine408 def: "Protein ACINU_HUMAN with the residue 408 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065339 name: ACINU_HUMAN-Phosphoserine410 def: "Protein ACINU_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065340 name: ACINU_HUMAN-Phosphothreonine414 def: "Protein ACINU_HUMAN with the residue 414 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065341 name: ACINU_HUMAN-Phosphoserine424 def: "Protein ACINU_HUMAN with the residue 424 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065342 name: ACINU_HUMAN-Phosphoserine425 def: "Protein ACINU_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065343 name: ACINU_HUMAN-Phosphoserine434 def: "Protein ACINU_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065344 name: ACINU_HUMAN-Phosphoserine453 def: "Protein ACINU_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065345 name: ACINU_HUMAN-Phosphoserine478 def: "Protein ACINU_HUMAN with the residue 478 substituted with Phosphoserine" [UniProtKB:Q9UKV3] comment: By similarity xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065346 name: ACINU_HUMAN-Phosphoserine490 def: "Protein ACINU_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065347 name: ACINU_HUMAN-Phosphotyrosine512 def: "Protein ACINU_HUMAN with the residue 512 substituted with Phosphotyrosine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065348 name: ACINU_HUMAN-Phosphoserine561 def: "Protein ACINU_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065349 name: ACINU_HUMAN-Phosphoserine655 def: "Protein ACINU_HUMAN with the residue 655 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065350 name: ACINU_HUMAN-Phosphoserine657 def: "Protein ACINU_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065351 name: ACINU_HUMAN-Phosphoserine661 def: "Protein ACINU_HUMAN with the residue 661 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065352 name: ACINU_HUMAN-Phosphoserine676 def: "Protein ACINU_HUMAN with the residue 676 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065353 name: ACINU_HUMAN-Phosphothreonine682 def: "Protein ACINU_HUMAN with the residue 682 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065354 name: ACINU_HUMAN-Phosphoserine710 def: "Protein ACINU_HUMAN with the residue 710 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065355 name: ACINU_HUMAN-Phosphoserine714 def: "Protein ACINU_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065356 name: ACINU_HUMAN-Phosphothreonine720 def: "Protein ACINU_HUMAN with the residue 720 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065357 name: ACINU_HUMAN-Phosphoserine729 def: "Protein ACINU_HUMAN with the residue 729 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065358 name: ACINU_HUMAN-Phosphoserine814 def: "Protein ACINU_HUMAN with the residue 814 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065359 name: ACINU_HUMAN-Phosphoserine815 def: "Protein ACINU_HUMAN with the residue 815 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065360 name: ACINU_HUMAN-Phosphothreonine830 def: "Protein ACINU_HUMAN with the residue 830 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065361 name: ACINU_HUMAN-Phosphoserine838 def: "Protein ACINU_HUMAN with the residue 838 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065362 name: ACINU_HUMAN-Phosphothreonine840 def: "Protein ACINU_HUMAN with the residue 840 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] comment: By similarity xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065363 name: ACINU_HUMAN-Phosphoserine895 def: "Protein ACINU_HUMAN with the residue 895 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065364 name: ACINU_HUMAN-Phosphoserine898 def: "Protein ACINU_HUMAN with the residue 898 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065365 name: ACINU_HUMAN-Phosphothreonine976 def: "Protein ACINU_HUMAN with the residue 976 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065366 name: ACINU_HUMAN-Phosphothreonine978 def: "Protein ACINU_HUMAN with the residue 978 substituted with Phosphothreonine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065367 name: ACINU_HUMAN-Phosphoserine981 def: "Protein ACINU_HUMAN with the residue 981 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065368 name: ACINU_HUMAN-Phosphoserine983 def: "Protein ACINU_HUMAN with the residue 983 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065369 name: ACINU_HUMAN-Phosphoserine1004 def: "Protein ACINU_HUMAN with the residue 1004 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065370 name: ACINU_HUMAN-Phosphoserine1176 def: "Protein ACINU_HUMAN with the residue 1176 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065371 name: ACINU_HUMAN-Phosphoserine1178 def: "Protein ACINU_HUMAN with the residue 1178 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065372 name: ACINU_HUMAN-Phosphoserine1180 def: "Protein ACINU_HUMAN with the residue 1180 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065373 name: ACINU_HUMAN-Phosphoserine1284 def: "Protein ACINU_HUMAN with the residue 1284 substituted with Phosphoserine" [UniProtKB:Q9UKV3] xref: UniProtKB:Q9UKV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:B0065374 name: ACM1_HUMAN-Phosphothreonine428 def: "Protein ACM1_HUMAN with the residue 428 substituted with Phosphothreonine" [UniProtKB:P11229] comment: Potential xref: UniProtKB:P11229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001319 ! muscarinic acetylcholine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0054986 ! ACM1_HUMAN [Term] id: CCO:B0065375 name: ACM1_HUMAN-Phosphoserine451 def: "Protein ACM1_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:P11229] comment: Potential xref: UniProtKB:P11229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054986 ! ACM1_HUMAN [Term] id: CCO:B0065376 name: ACM1_HUMAN-Phosphothreonine455 def: "Protein ACM1_HUMAN with the residue 455 substituted with Phosphothreonine" [UniProtKB:P11229] comment: Potential xref: UniProtKB:P11229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054986 ! ACM1_HUMAN [Term] id: CCO:B0065377 name: ACM1_HUMAN-Phosphoserine457 def: "Protein ACM1_HUMAN with the residue 457 substituted with Phosphoserine" [UniProtKB:P11229] comment: Potential xref: UniProtKB:P11229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054986 ! ACM1_HUMAN [Term] id: CCO:B0065378 name: ACM2_HUMAN-Phosphoserine232 def: "Protein ACM2_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:P08172] comment: By similarity xref: UniProtKB:P08172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054923 ! ACM2_HUMAN [Term] id: CCO:B0065379 name: ACM2_HUMAN-Phosphoserine234 def: "Protein ACM2_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:P08172] comment: By similarity xref: UniProtKB:P08172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001319 ! muscarinic acetylcholine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0054923 ! ACM2_HUMAN [Term] id: CCO:B0065380 name: ACM2_HUMAN-Phosphothreonine446 def: "Protein ACM2_HUMAN with the residue 446 substituted with Phosphothreonine" [UniProtKB:P08172] comment: Potential xref: UniProtKB:P08172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054923 ! ACM2_HUMAN [Term] id: CCO:B0065381 name: ACM2_HUMAN-Phosphothreonine450 def: "Protein ACM2_HUMAN with the residue 450 substituted with Phosphothreonine" [UniProtKB:P08172] comment: Potential xref: UniProtKB:P08172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054923 ! ACM2_HUMAN [Term] id: CCO:B0065382 name: ACM2_HUMAN-Phosphothreonine465 def: "Protein ACM2_HUMAN with the residue 465 substituted with Phosphothreonine" [UniProtKB:P08172] comment: Potential xref: UniProtKB:P08172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054923 ! ACM2_HUMAN [Term] id: CCO:B0065383 name: ACM4_HUMAN-Phosphothreonine459 def: "Protein ACM4_HUMAN with the residue 459 substituted with Phosphothreonine" [UniProtKB:P08173] comment: Potential xref: UniProtKB:P08173 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001319 ! muscarinic acetylcholine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0054924 ! ACM4_HUMAN [Term] id: CCO:B0065384 name: ACM4_HUMAN-Phosphothreonine463 def: "Protein ACM4_HUMAN with the residue 463 substituted with Phosphothreonine" [UniProtKB:P08173] comment: Potential xref: UniProtKB:P08173 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054924 ! ACM4_HUMAN [Term] id: CCO:B0065385 name: ACM4_HUMAN-Phosphothreonine477 def: "Protein ACM4_HUMAN with the residue 477 substituted with Phosphothreonine" [UniProtKB:P08173] comment: Potential xref: UniProtKB:P08173 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054924 ! ACM4_HUMAN [Term] id: CCO:B0065386 name: ACM5_HUMAN-Phosphothreonine501 def: "Protein ACM5_HUMAN with the residue 501 substituted with Phosphothreonine" [UniProtKB:P08912] comment: Potential xref: UniProtKB:P08912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001319 ! muscarinic acetylcholine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0054936 ! ACM5_HUMAN [Term] id: CCO:B0065387 name: ACM5_HUMAN-Phosphothreonine505 def: "Protein ACM5_HUMAN with the residue 505 substituted with Phosphothreonine" [UniProtKB:P08912] comment: Potential xref: UniProtKB:P08912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054936 ! ACM5_HUMAN [Term] id: CCO:B0065388 name: ACO11_HUMAN-Phosphoserine367 def: "Protein ACO11_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q8WXI4] xref: UniProtKB:Q8WXI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000566 ! carboxylesterase activity relationship: has_function CCO:F0003107 ! acyl-CoA thioesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058024 ! ACO11_HUMAN [Term] id: CCO:B0065389 name: ACSL1_HUMAN-N-acetylmethionine1 def: "Protein ACSL1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P33121] xref: UniProtKB:P33121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000867 ! long-chain-fatty-acid-CoA ligase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055264 ! ACSL1_HUMAN [Term] id: CCO:B0065390 name: ACSL1_HUMAN-Phosphotyrosine84 def: "Protein ACSL1_HUMAN with the residue 84 substituted with Phosphotyrosine" [UniProtKB:P33121] comment: By similarity xref: UniProtKB:P33121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055264 ! ACSL1_HUMAN [Term] id: CCO:B0065391 name: ACSL1_HUMAN-N6-acetyllysine543 def: "Protein ACSL1_HUMAN with the residue 543 substituted with N6-acetyllysine" [UniProtKB:P33121] comment: By similarity xref: UniProtKB:P33121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055264 ! ACSL1_HUMAN [Term] id: CCO:B0065392 name: ACSL1_HUMAN-N6-acetyllysine632 def: "Protein ACSL1_HUMAN with the residue 632 substituted with N6-acetyllysine" [UniProtKB:P33121] comment: By similarity xref: UniProtKB:P33121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055264 ! ACSL1_HUMAN [Term] id: CCO:B0065393 name: ACTB_HUMAN-Phosphotyrosine53 def: "Protein ACTB_HUMAN with the residue 53 substituted with Phosphotyrosine" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0065394 name: ACTB_HUMAN-Phosphotyrosine91 def: "Protein ACTB_HUMAN with the residue 91 substituted with Phosphotyrosine" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0065395 name: ACTB_HUMAN-Phosphotyrosine198 def: "Protein ACTB_HUMAN with the residue 198 substituted with Phosphotyrosine" [UniProtKB:P60709] xref: UniProtKB:P60709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:B0065396 name: ACTG_HUMAN-Phosphotyrosine198 def: "Protein ACTG_HUMAN with the residue 198 substituted with Phosphotyrosine" [UniProtKB:P63261] xref: UniProtKB:P63261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:B0065397 name: ACTG_HUMAN-Phosphotyrosine294 def: "Protein ACTG_HUMAN with the residue 294 substituted with Phosphotyrosine" [UniProtKB:P63261] xref: UniProtKB:P63261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:B0065398 name: ACTN1_HUMAN-Phosphotyrosine193 def: "Protein ACTN1_HUMAN with the residue 193 substituted with Phosphotyrosine" [UniProtKB:P12814] xref: UniProtKB:P12814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:B0065399 name: ADA2A_HUMAN-Phosphoserine297 def: "Protein ADA2A_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:P08913] xref: UniProtKB:P08913 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054937 ! ADA2A_HUMAN [Term] id: CCO:B0065400 name: ADA2A_HUMAN-Phosphoserine298 def: "Protein ADA2A_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:P08913] xref: UniProtKB:P08913 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054937 ! ADA2A_HUMAN [Term] id: CCO:B0065401 name: ADA2A_HUMAN-Phosphoserine299 def: "Protein ADA2A_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:P08913] xref: UniProtKB:P08913 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054937 ! ADA2A_HUMAN [Term] id: CCO:B0065402 name: ADAM9_HUMAN-Phosphotyrosine815 def: "Protein ADAM9_HUMAN with the residue 815 substituted with Phosphotyrosine" [UniProtKB:Q13443] xref: UniProtKB:Q13443 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005372 ! ADAM9_HUMAN [Term] id: CCO:B0065403 name: ADA_HUMAN-N-acetylalanine2 def: "Protein ADA_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P00813] xref: UniProtKB:P00813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000485 ! adenosine deaminase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004140 ! deaminase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054829 ! ADA_HUMAN [Term] id: CCO:B0065404 name: ADCY5_HUMAN-Phosphoserine8 def: "Protein ADCY5_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:O95622] comment: By similarity xref: UniProtKB:O95622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054773 ! ADCY5_HUMAN [Term] id: CCO:B0065405 name: ADCY6_HUMAN-Phosphoserine54 def: "Protein ADCY6_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:O43306] xref: UniProtKB:O43306 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054469 ! ADCY6_HUMAN [Term] id: CCO:B0065406 name: ADCY6_HUMAN-Phosphoserine576 def: "Protein ADCY6_HUMAN with the residue 576 substituted with Phosphoserine" [UniProtKB:O43306] xref: UniProtKB:O43306 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054469 ! ADCY6_HUMAN [Term] id: CCO:B0065407 name: ADCY9_HUMAN-Phosphoserine365 def: "Protein ADCY9_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:O60503] xref: UniProtKB:O60503 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054563 ! ADCY9_HUMAN [Term] id: CCO:B0065408 name: ADCY9_HUMAN-Phosphothreonine608 def: "Protein ADCY9_HUMAN with the residue 608 substituted with Phosphothreonine" [UniProtKB:O60503] comment: By similarity xref: UniProtKB:O60503 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054563 ! ADCY9_HUMAN [Term] id: CCO:B0065409 name: ADCY9_HUMAN-Phosphoserine610 def: "Protein ADCY9_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:O60503] comment: By similarity xref: UniProtKB:O60503 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054563 ! ADCY9_HUMAN [Term] id: CCO:B0065410 name: ADCYA_HUMAN-Phosphothreonine809 def: "Protein ADCYA_HUMAN with the residue 809 substituted with Phosphothreonine" [UniProtKB:Q96PN6] xref: UniProtKB:Q96PN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000494 ! adenylate cyclase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003413 ! phosphorus-oxygen lyase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058339 ! ADCYA_HUMAN [Term] id: CCO:B0065411 name: ADCYA_HUMAN-Phosphoserine810 def: "Protein ADCYA_HUMAN with the residue 810 substituted with Phosphoserine" [UniProtKB:Q96PN6] xref: UniProtKB:Q96PN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058339 ! ADCYA_HUMAN [Term] id: CCO:B0065412 name: ADIPO_HUMAN-5-hydroxylysine33 def: "Protein ADIPO_HUMAN with the residue 33 substituted with 5-hydroxylysine" [UniProtKB:Q15848] comment: Probable xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065413 name: ADIPO_HUMAN-4-hydroxyproline44 def: "Protein ADIPO_HUMAN with the residue 44 substituted with 4-hydroxyproline" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065414 name: ADIPO_HUMAN-4-hydroxyproline47 def: "Protein ADIPO_HUMAN with the residue 47 substituted with 4-hydroxyproline" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065415 name: ADIPO_HUMAN-4-hydroxyproline53 def: "Protein ADIPO_HUMAN with the residue 53 substituted with 4-hydroxyproline" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065416 name: ADIPO_HUMAN-5-hydroxylysine65 def: "Protein ADIPO_HUMAN with the residue 65 substituted with 5-hydroxylysine" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065417 name: ADIPO_HUMAN-5-hydroxylysine68 def: "Protein ADIPO_HUMAN with the residue 68 substituted with 5-hydroxylysine" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065418 name: ADIPO_HUMAN-4-hydroxyproline71 def: "Protein ADIPO_HUMAN with the residue 71 substituted with 4-hydroxyproline" [UniProtKB:Q15848] comment: partial; xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065419 name: ADIPO_HUMAN-4-hydroxyproline76 def: "Protein ADIPO_HUMAN with the residue 76 substituted with 4-hydroxyproline" [UniProtKB:Q15848] comment: partial; xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065420 name: ADIPO_HUMAN-5-hydroxylysine77 def: "Protein ADIPO_HUMAN with the residue 77 substituted with 5-hydroxylysine" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065421 name: ADIPO_HUMAN-4-hydroxyproline91 def: "Protein ADIPO_HUMAN with the residue 91 substituted with 4-hydroxyproline" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065422 name: ADIPO_HUMAN-4-hydroxyproline95 def: "Protein ADIPO_HUMAN with the residue 95 substituted with 4-hydroxyproline" [UniProtKB:Q15848] comment: partial; xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065423 name: ADIPO_HUMAN-5-hydroxylysine101 def: "Protein ADIPO_HUMAN with the residue 101 substituted with 5-hydroxylysine" [UniProtKB:Q15848] xref: UniProtKB:Q15848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:B0065424 name: ADML_HUMAN-Arginine amide41 def: "Protein ADML_HUMAN with the residue 41 substituted with Arginine amide" [UniProtKB:P35318] xref: UniProtKB:P35318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055286 ! ADML_HUMAN [Term] id: CCO:B0065425 name: ADML_HUMAN-Tyrosine amide146 def: "Protein ADML_HUMAN with the residue 146 substituted with Tyrosine amide" [UniProtKB:P35318] xref: UniProtKB:P35318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055286 ! ADML_HUMAN [Term] id: CCO:B0065426 name: ADNP_HUMAN-Phosphoserine98 def: "Protein ADNP_HUMAN with the residue 98 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065427 name: ADNP_HUMAN-Phosphoserine409 def: "Protein ADNP_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065428 name: ADNP_HUMAN-Phosphoserine413 def: "Protein ADNP_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065429 name: ADNP_HUMAN-Phosphoserine709 def: "Protein ADNP_HUMAN with the residue 709 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065430 name: ADNP_HUMAN-Phosphoserine736 def: "Protein ADNP_HUMAN with the residue 736 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065431 name: ADNP_HUMAN-Phosphoserine876 def: "Protein ADNP_HUMAN with the residue 876 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065432 name: ADNP_HUMAN-Phosphoserine878 def: "Protein ADNP_HUMAN with the residue 878 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065433 name: ADNP_HUMAN-Phosphoserine953 def: "Protein ADNP_HUMAN with the residue 953 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065434 name: ADNP_HUMAN-Phosphoserine955 def: "Protein ADNP_HUMAN with the residue 955 substituted with Phosphoserine" [UniProtKB:Q9H2P0] xref: UniProtKB:Q9H2P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058688 ! ADNP_HUMAN [Term] id: CCO:B0065435 name: ADPPT_HUMAN-Phosphoserine258 def: "Protein ADPPT_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q9NRN7] xref: UniProtKB:Q9NRN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008384 ! holo-[acyl-carrier-protein] synthase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0062778 ! ADPPT_HUMAN [Term] id: CCO:B0065436 name: ADRB1_HUMAN-Phosphoserine312 def: "Protein ADRB1_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:P08588] comment: by PKA; Potential xref: UniProtKB:P08588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054929 ! ADRB1_HUMAN [Term] id: CCO:B0065437 name: ADRB1_HUMAN-Phosphoserine412 def: "Protein ADRB1_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:P08588] comment: by PKA; Potential xref: UniProtKB:P08588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054929 ! ADRB1_HUMAN [Term] id: CCO:B0065438 name: ADRB2_HUMAN-Phosphoserine246 def: "Protein ADRB2_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:P07550] xref: UniProtKB:P07550 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:B0065439 name: ADRB2_HUMAN-Phosphoserine261 def: "Protein ADRB2_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:P07550] comment: by PKA; Potential xref: UniProtKB:P07550 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001277 ! adrenoceptor activity relationship: has_function CCO:F0001281 ! beta-adrenergic receptor activity relationship: has_function CCO:F0001283 ! beta2-adrenergic receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0008089 ! norepinephrine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001638 ! sarcolemma relationship: located_in CCO:C0001751 ! receptor complex relationship: located_in CCO:C0001843 ! intracellular part relationship: transformation_of CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:B0065440 name: ADRB2_HUMAN-Phosphoserine262 def: "Protein ADRB2_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:P07550] comment: by PKA; Potential xref: UniProtKB:P07550 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:B0065441 name: ADRB2_HUMAN-Phosphoserine345 def: "Protein ADRB2_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:P07550] comment: by PKA; xref: UniProtKB:P07550 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:B0065442 name: ADRB2_HUMAN-Phosphoserine346 def: "Protein ADRB2_HUMAN with the residue 346 substituted with Phosphoserine" [UniProtKB:P07550] comment: by PKA; xref: UniProtKB:P07550 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:B0065443 name: ADRB2_HUMAN-Phosphoserine355 def: "Protein ADRB2_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:P07550] comment: by BARK; Probable xref: UniProtKB:P07550 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:B0065444 name: ADRB2_HUMAN-Phosphoserine356 def: "Protein ADRB2_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:P07550] comment: by BARK; Probable xref: UniProtKB:P07550 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:B0065445 name: ADT1_HUMAN-N-acetylglycine2 def: "Protein ADT1_HUMAN with the residue 2 substituted with N-acetylglycine" [UniProtKB:P12235] xref: UniProtKB:P12235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063358 ! ADT1_HUMAN [Term] id: CCO:B0065446 name: ADT1_HUMAN-Phosphothreonine126 def: "Protein ADT1_HUMAN with the residue 126 substituted with Phosphothreonine" [UniProtKB:P12235] comment: By similarity xref: UniProtKB:P12235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063358 ! ADT1_HUMAN [Term] id: CCO:B0065447 name: ADT1_HUMAN-Phosphoserine127 def: "Protein ADT1_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:P12235] comment: By similarity xref: UniProtKB:P12235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063358 ! ADT1_HUMAN [Term] id: CCO:B0065448 name: ADT1_HUMAN-Phosphotyrosine191 def: "Protein ADT1_HUMAN with the residue 191 substituted with Phosphotyrosine" [UniProtKB:P12235] xref: UniProtKB:P12235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063358 ! ADT1_HUMAN [Term] id: CCO:B0065449 name: ADT1_HUMAN-Phosphotyrosine195 def: "Protein ADT1_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:P12235] comment: By similarity xref: UniProtKB:P12235 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063358 ! ADT1_HUMAN [Term] id: CCO:B0065450 name: ADT3_HUMAN-N-acetylthreonine2 def: "Protein ADT3_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P12236] xref: UniProtKB:P12236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001626 ! ATP:ADP antiporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000330 ! mitochondrial inner membrane presequence translocase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:B0065451 name: ADT3_HUMAN-Phosphotyrosine191 def: "Protein ADT3_HUMAN with the residue 191 substituted with Phosphotyrosine" [UniProtKB:P12236] xref: UniProtKB:P12236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:B0065452 name: AEBP2_HUMAN-Phosphoserine18 def: "Protein AEBP2_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q6ZN18] xref: UniProtKB:Q6ZN18 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057006 ! AEBP2_HUMAN [Term] id: CCO:B0065453 name: AEBP2_HUMAN-Phosphoserine24 def: "Protein AEBP2_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q6ZN18] xref: UniProtKB:Q6ZN18 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057006 ! AEBP2_HUMAN [Term] id: CCO:B0065454 name: AEBP2_HUMAN-Phosphoserine27 def: "Protein AEBP2_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q6ZN18] xref: UniProtKB:Q6ZN18 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057006 ! AEBP2_HUMAN [Term] id: CCO:B0065455 name: AEBP2_HUMAN-Phosphoserine206 def: "Protein AEBP2_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q6ZN18] xref: UniProtKB:Q6ZN18 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057006 ! AEBP2_HUMAN [Term] id: CCO:B0065456 name: AEBP2_HUMAN-Phosphoserine210 def: "Protein AEBP2_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:Q6ZN18] xref: UniProtKB:Q6ZN18 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057006 ! AEBP2_HUMAN [Term] id: CCO:B0065457 name: AEBP2_HUMAN-Phosphoserine211 def: "Protein AEBP2_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:Q6ZN18] xref: UniProtKB:Q6ZN18 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057006 ! AEBP2_HUMAN [Term] id: CCO:B0065458 name: AF1L2_HUMAN-Phosphotyrosine383 def: "Protein AF1L2_HUMAN with the residue 383 substituted with Phosphotyrosine" [UniProtKB:Q8N4X5] xref: UniProtKB:Q8N4X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001964 ! AF1L2_HUMAN [Term] id: CCO:B0065459 name: AF9_HUMAN-Phosphoserine288 def: "Protein AF9_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:P42568] xref: UniProtKB:P42568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:B0065460 name: AF9_HUMAN-Phosphoserine294 def: "Protein AF9_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:P42568] xref: UniProtKB:P42568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:B0065461 name: AF9_HUMAN-Phosphoserine412 def: "Protein AF9_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:P42568] xref: UniProtKB:P42568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:B0065462 name: AF9_HUMAN-Phosphoserine419 def: "Protein AF9_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:P42568] xref: UniProtKB:P42568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:B0065463 name: AF9_HUMAN-Phosphoserine429 def: "Protein AF9_HUMAN with the residue 429 substituted with Phosphoserine" [UniProtKB:P42568] xref: UniProtKB:P42568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:B0065464 name: AF9_HUMAN-Phosphoserine483 def: "Protein AF9_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:P42568] xref: UniProtKB:P42568 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:B0065465 name: AFAD_HUMAN-Phosphotyrosine94 def: "Protein AFAD_HUMAN with the residue 94 substituted with Phosphotyrosine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0065466 name: AFAD_HUMAN-Phosphoserine215 def: "Protein AFAD_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0065467 name: AFAD_HUMAN-Phosphotyrosine1213 def: "Protein AFAD_HUMAN with the residue 1213 substituted with Phosphotyrosine" [UniProtKB:P55196] comment: By similarity xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0065468 name: AFAD_HUMAN-Phosphothreonine1215 def: "Protein AFAD_HUMAN with the residue 1215 substituted with Phosphothreonine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0065469 name: AFAD_HUMAN-Phosphoserine1679 def: "Protein AFAD_HUMAN with the residue 1679 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0065470 name: AFAD_HUMAN-Phosphoserine1704 def: "Protein AFAD_HUMAN with the residue 1704 substituted with Phosphoserine" [UniProtKB:P55196] xref: UniProtKB:P55196 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:B0065471 name: AFF3_HUMAN-Phosphothreonine310 def: "Protein AFF3_HUMAN with the residue 310 substituted with Phosphothreonine" [UniProtKB:P51826] xref: UniProtKB:P51826 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055482 ! AFF3_HUMAN [Term] id: CCO:B0065472 name: AFF3_HUMAN-Phosphoserine316 def: "Protein AFF3_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:P51826] xref: UniProtKB:P51826 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055482 ! AFF3_HUMAN [Term] id: CCO:B0065473 name: AFF4_HUMAN-Phosphoserine387 def: "Protein AFF4_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065474 name: AFF4_HUMAN-Phosphoserine388 def: "Protein AFF4_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065475 name: AFF4_HUMAN-Phosphoserine389 def: "Protein AFF4_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065476 name: AFF4_HUMAN-Phosphoserine392 def: "Protein AFF4_HUMAN with the residue 392 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065477 name: AFF4_HUMAN-Phosphoserine499 def: "Protein AFF4_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065478 name: AFF4_HUMAN-Phosphoserine549 def: "Protein AFF4_HUMAN with the residue 549 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065479 name: AFF4_HUMAN-Phosphothreonine674 def: "Protein AFF4_HUMAN with the residue 674 substituted with Phosphothreonine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065480 name: AFF4_HUMAN-Phosphoserine694 def: "Protein AFF4_HUMAN with the residue 694 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065481 name: AFF4_HUMAN-Phosphoserine703 def: "Protein AFF4_HUMAN with the residue 703 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065482 name: AFF4_HUMAN-Phosphoserine706 def: "Protein AFF4_HUMAN with the residue 706 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065483 name: AFF4_HUMAN-Phosphotyrosine712 def: "Protein AFF4_HUMAN with the residue 712 substituted with Phosphotyrosine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065484 name: AFF4_HUMAN-Phosphoserine1043 def: "Protein AFF4_HUMAN with the residue 1043 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065485 name: AFF4_HUMAN-Phosphoserine1055 def: "Protein AFF4_HUMAN with the residue 1055 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065486 name: AFF4_HUMAN-Phosphoserine1058 def: "Protein AFF4_HUMAN with the residue 1058 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065487 name: AFF4_HUMAN-Phosphoserine1062 def: "Protein AFF4_HUMAN with the residue 1062 substituted with Phosphoserine" [UniProtKB:Q9UHB7] xref: UniProtKB:Q9UHB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059133 ! AFF4_HUMAN [Term] id: CCO:B0065488 name: AHDC1_HUMAN-Phosphoserine70 def: "Protein AHDC1_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:Q5TGY3] xref: UniProtKB:Q5TGY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:B0065489 name: AHDC1_HUMAN-Phosphoserine829 def: "Protein AHDC1_HUMAN with the residue 829 substituted with Phosphoserine" [UniProtKB:Q5TGY3] xref: UniProtKB:Q5TGY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:B0065490 name: AHDC1_HUMAN-Phosphoserine846 def: "Protein AHDC1_HUMAN with the residue 846 substituted with Phosphoserine" [UniProtKB:Q5TGY3] xref: UniProtKB:Q5TGY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:B0065491 name: AHDC1_HUMAN-Phosphoserine1399 def: "Protein AHDC1_HUMAN with the residue 1399 substituted with Phosphoserine" [UniProtKB:Q5TGY3] xref: UniProtKB:Q5TGY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:B0065492 name: AHDC1_HUMAN-Phosphoserine1403 def: "Protein AHDC1_HUMAN with the residue 1403 substituted with Phosphoserine" [UniProtKB:Q5TGY3] xref: UniProtKB:Q5TGY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:B0065493 name: AHDC1_HUMAN-Phosphoserine1549 def: "Protein AHDC1_HUMAN with the residue 1549 substituted with Phosphoserine" [UniProtKB:Q5TGY3] xref: UniProtKB:Q5TGY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:B0065494 name: AIDA_HUMAN-Phosphoserine144 def: "Protein AIDA_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q96BJ3] xref: UniProtKB:Q96BJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0058165 ! AIDA_HUMAN [Term] id: CCO:B0065495 name: AKA11_HUMAN-Phosphoserine422 def: "Protein AKA11_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q9UKA4] xref: UniProtKB:Q9UKA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059189 ! AKA11_HUMAN [Term] id: CCO:B0065496 name: AKA11_HUMAN-Phosphoserine433 def: "Protein AKA11_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:Q9UKA4] xref: UniProtKB:Q9UKA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059189 ! AKA11_HUMAN [Term] id: CCO:B0065497 name: AKA11_HUMAN-Phosphoserine448 def: "Protein AKA11_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:Q9UKA4] xref: UniProtKB:Q9UKA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059189 ! AKA11_HUMAN [Term] id: CCO:B0065498 name: AKA11_HUMAN-Phosphothreonine1100 def: "Protein AKA11_HUMAN with the residue 1100 substituted with Phosphothreonine" [UniProtKB:Q9UKA4] xref: UniProtKB:Q9UKA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059189 ! AKA11_HUMAN [Term] id: CCO:B0065499 name: AKA11_HUMAN-Phosphothreonine1104 def: "Protein AKA11_HUMAN with the residue 1104 substituted with Phosphothreonine" [UniProtKB:Q9UKA4] xref: UniProtKB:Q9UKA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059189 ! AKA11_HUMAN [Term] id: CCO:B0065500 name: AKA11_HUMAN-Phosphoserine1337 def: "Protein AKA11_HUMAN with the residue 1337 substituted with Phosphoserine" [UniProtKB:Q9UKA4] xref: UniProtKB:Q9UKA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059189 ! AKA11_HUMAN [Term] id: CCO:B0065501 name: AKA11_HUMAN-Phosphoserine1340 def: "Protein AKA11_HUMAN with the residue 1340 substituted with Phosphoserine" [UniProtKB:Q9UKA4] xref: UniProtKB:Q9UKA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059189 ! AKA11_HUMAN [Term] id: CCO:B0065502 name: AKA12_HUMAN-Phosphoserine19 def: "Protein AKA12_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065503 name: AKA12_HUMAN-Phosphoserine219 def: "Protein AKA12_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065504 name: AKA12_HUMAN-Phosphoserine253 def: "Protein AKA12_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065505 name: AKA12_HUMAN-Phosphoserine283 def: "Protein AKA12_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065506 name: AKA12_HUMAN-Phosphoserine286 def: "Protein AKA12_HUMAN with the residue 286 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065507 name: AKA12_HUMAN-Phosphoserine312 def: "Protein AKA12_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065508 name: AKA12_HUMAN-Phosphoserine388 def: "Protein AKA12_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065509 name: AKA12_HUMAN-Phosphoserine483 def: "Protein AKA12_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065510 name: AKA12_HUMAN-Phosphoserine505 def: "Protein AKA12_HUMAN with the residue 505 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065511 name: AKA12_HUMAN-Phosphoserine565 def: "Protein AKA12_HUMAN with the residue 565 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008036 ! protein kinase A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065512 name: AKA12_HUMAN-Phosphoserine566 def: "Protein AKA12_HUMAN with the residue 566 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065513 name: AKA12_HUMAN-Phosphoserine568 def: "Protein AKA12_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065514 name: AKA12_HUMAN-Phosphoserine569 def: "Protein AKA12_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065515 name: AKA12_HUMAN-Phosphoserine598 def: "Protein AKA12_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065516 name: AKA12_HUMAN-Phosphoserine612 def: "Protein AKA12_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065517 name: AKA12_HUMAN-Phosphoserine627 def: "Protein AKA12_HUMAN with the residue 627 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065518 name: AKA12_HUMAN-Phosphoserine629 def: "Protein AKA12_HUMAN with the residue 629 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065519 name: AKA12_HUMAN-Phosphoserine645 def: "Protein AKA12_HUMAN with the residue 645 substituted with Phosphoserine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065520 name: AKA12_HUMAN-Phosphothreonine646 def: "Protein AKA12_HUMAN with the residue 646 substituted with Phosphothreonine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065521 name: AKA12_HUMAN-Phosphoserine648 def: "Protein AKA12_HUMAN with the residue 648 substituted with Phosphoserine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065522 name: AKA12_HUMAN-Phosphoserine696 def: "Protein AKA12_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065523 name: AKA12_HUMAN-Phosphoserine697 def: "Protein AKA12_HUMAN with the residue 697 substituted with Phosphoserine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065524 name: AKA12_HUMAN-Phosphoserine698 def: "Protein AKA12_HUMAN with the residue 698 substituted with Phosphoserine" [UniProtKB:Q02952] comment: By similarity xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065525 name: AKA12_HUMAN-Phosphoserine732 def: "Protein AKA12_HUMAN with the residue 732 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065526 name: AKA12_HUMAN-Phosphoserine887 def: "Protein AKA12_HUMAN with the residue 887 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065527 name: AKA12_HUMAN-Phosphoserine1331 def: "Protein AKA12_HUMAN with the residue 1331 substituted with Phosphoserine" [UniProtKB:Q02952] xref: UniProtKB:Q02952 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055718 ! AKA12_HUMAN [Term] id: CCO:B0065528 name: AKAP3_HUMAN-Phosphoserine205 def: "Protein AKAP3_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065529 name: AKAP3_HUMAN-Phosphoserine208 def: "Protein AKAP3_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065530 name: AKAP3_HUMAN-Phosphoserine403 def: "Protein AKAP3_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065531 name: AKAP3_HUMAN-Phosphotyrosine404 def: "Protein AKAP3_HUMAN with the residue 404 substituted with Phosphotyrosine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065532 name: AKAP3_HUMAN-Phosphoserine440 def: "Protein AKAP3_HUMAN with the residue 440 substituted with Phosphoserine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065533 name: AKAP3_HUMAN-Phosphoserine612 def: "Protein AKAP3_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008036 ! protein kinase A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000177 ! acrosome relationship: located_in CCO:C0000629 ! microtubule-based flagellum relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065534 name: AKAP3_HUMAN-Phosphoserine635 def: "Protein AKAP3_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065535 name: AKAP3_HUMAN-Phosphoserine636 def: "Protein AKAP3_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:O75969] xref: UniProtKB:O75969 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054682 ! AKAP3_HUMAN [Term] id: CCO:B0065536 name: AKAP4_HUMAN-Phosphoserine62 def: "Protein AKAP4_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065537 name: AKAP4_HUMAN-Phosphoserine63 def: "Protein AKAP4_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065538 name: AKAP4_HUMAN-Phosphoserine64 def: "Protein AKAP4_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065539 name: AKAP4_HUMAN-Phosphoserine65 def: "Protein AKAP4_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065540 name: AKAP4_HUMAN-Phosphoserine151 def: "Protein AKAP4_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065541 name: AKAP4_HUMAN-Phosphothreonine265 def: "Protein AKAP4_HUMAN with the residue 265 substituted with Phosphothreonine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065542 name: AKAP4_HUMAN-Phosphoserine268 def: "Protein AKAP4_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065543 name: AKAP4_HUMAN-Phosphoserine272 def: "Protein AKAP4_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065544 name: AKAP4_HUMAN-Phosphoserine293 def: "Protein AKAP4_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065545 name: AKAP4_HUMAN-Phosphoserine300 def: "Protein AKAP4_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065546 name: AKAP4_HUMAN-Phosphotyrosine303 def: "Protein AKAP4_HUMAN with the residue 303 substituted with Phosphotyrosine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065547 name: AKAP4_HUMAN-Phosphoserine304 def: "Protein AKAP4_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065548 name: AKAP4_HUMAN-Phosphoserine447 def: "Protein AKAP4_HUMAN with the residue 447 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065549 name: AKAP4_HUMAN-Phosphotyrosine448 def: "Protein AKAP4_HUMAN with the residue 448 substituted with Phosphotyrosine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065550 name: AKAP4_HUMAN-Phosphoserine450 def: "Protein AKAP4_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065551 name: AKAP4_HUMAN-Phosphoserine492 def: "Protein AKAP4_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008036 ! protein kinase A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000481 ! cilium relationship: located_in CCO:C0000501 ! cAMP-dependent protein kinase complex relationship: located_in CCO:C0000629 ! microtubule-based flagellum relationship: located_in CCO:C0000896 ! flagellum relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065552 name: AKAP4_HUMAN-Phosphoserine536 def: "Protein AKAP4_HUMAN with the residue 536 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065553 name: AKAP4_HUMAN-Phosphoserine539 def: "Protein AKAP4_HUMAN with the residue 539 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065554 name: AKAP4_HUMAN-Phosphoserine665 def: "Protein AKAP4_HUMAN with the residue 665 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065555 name: AKAP4_HUMAN-Phosphoserine667 def: "Protein AKAP4_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:Q5JQC9] xref: UniProtKB:Q5JQC9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056456 ! AKAP4_HUMAN [Term] id: CCO:B0065556 name: AKIR2_HUMAN-Phosphoserine18 def: "Protein AKIR2_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q53H80] xref: UniProtKB:Q53H80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062797 ! AKIR2_HUMAN [Term] id: CCO:B0065557 name: AKIR2_HUMAN-Phosphoserine21 def: "Protein AKIR2_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q53H80] xref: UniProtKB:Q53H80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062797 ! AKIR2_HUMAN [Term] id: CCO:B0065558 name: AKNA_HUMAN-Phosphoserine839 def: "Protein AKNA_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:Q7Z591] xref: UniProtKB:Q7Z591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057176 ! AKNA_HUMAN [Term] id: CCO:B0065559 name: AKNA_HUMAN-Phosphoserine848 def: "Protein AKNA_HUMAN with the residue 848 substituted with Phosphoserine" [UniProtKB:Q7Z591] xref: UniProtKB:Q7Z591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057176 ! AKNA_HUMAN [Term] id: CCO:B0065560 name: AKP13_HUMAN-Phosphoserine983 def: "Protein AKP13_HUMAN with the residue 983 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065561 name: AKP13_HUMAN-Phosphoserine1559 def: "Protein AKP13_HUMAN with the residue 1559 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065562 name: AKP13_HUMAN-Phosphoserine1645 def: "Protein AKP13_HUMAN with the residue 1645 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065563 name: AKP13_HUMAN-Phosphoserine1647 def: "Protein AKP13_HUMAN with the residue 1647 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065564 name: AKP13_HUMAN-Phosphoserine1876 def: "Protein AKP13_HUMAN with the residue 1876 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065565 name: AKP13_HUMAN-Phosphoserine1929 def: "Protein AKP13_HUMAN with the residue 1929 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001058 ! cAMP-dependent protein kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065566 name: AKP13_HUMAN-Phosphoserine1932 def: "Protein AKP13_HUMAN with the residue 1932 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065567 name: AKP13_HUMAN-Phosphoserine2398 def: "Protein AKP13_HUMAN with the residue 2398 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065568 name: AKP13_HUMAN-Phosphoserine2402 def: "Protein AKP13_HUMAN with the residue 2402 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065569 name: AKP13_HUMAN-Phosphoserine2703 def: "Protein AKP13_HUMAN with the residue 2703 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065570 name: AKP13_HUMAN-Phosphoserine2709 def: "Protein AKP13_HUMAN with the residue 2709 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065571 name: AKP13_HUMAN-Phosphoserine2728 def: "Protein AKP13_HUMAN with the residue 2728 substituted with Phosphoserine" [UniProtKB:Q12802] xref: UniProtKB:Q12802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055843 ! AKP13_HUMAN [Term] id: CCO:B0065572 name: AKP8L_HUMAN-Phosphothreonine292 def: "Protein AKP8L_HUMAN with the residue 292 substituted with Phosphothreonine" [UniProtKB:Q9ULX6] xref: UniProtKB:Q9ULX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:B0065573 name: AKP8L_HUMAN-Phosphothreonine294 def: "Protein AKP8L_HUMAN with the residue 294 substituted with Phosphothreonine" [UniProtKB:Q9ULX6] xref: UniProtKB:Q9ULX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:B0065574 name: AKP8L_HUMAN-Phosphoserine297 def: "Protein AKP8L_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:Q9ULX6] xref: UniProtKB:Q9ULX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003596 ! DEAD/H-box RNA helicase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:B0065575 name: AKP8L_HUMAN-Phosphoserine300 def: "Protein AKP8L_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q9ULX6] xref: UniProtKB:Q9ULX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:B0065576 name: AKP8L_HUMAN-Phosphoserine302 def: "Protein AKP8L_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:Q9ULX6] xref: UniProtKB:Q9ULX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:B0065577 name: AKP8L_HUMAN-Phosphothreonine308 def: "Protein AKP8L_HUMAN with the residue 308 substituted with Phosphothreonine" [UniProtKB:Q9ULX6] xref: UniProtKB:Q9ULX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:B0065578 name: AKT2_HUMAN-Phosphoserine126 def: "Protein AKT2_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:P31751] xref: UniProtKB:P31751 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005910 ! AKT2_HUMAN [Term] id: CCO:B0065579 name: AKTS1_HUMAN-Phosphoserine88 def: "Protein AKTS1_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q96B36] xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065580 name: AKTS1_HUMAN-Phosphoserine92 def: "Protein AKTS1_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q96B36] xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065581 name: AKTS1_HUMAN-Phosphoserine116 def: "Protein AKTS1_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q96B36] comment: By similarity xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001864 ! cytosolic part relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065582 name: AKTS1_HUMAN-Phosphoserine183 def: "Protein AKTS1_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q96B36] xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065583 name: AKTS1_HUMAN-Phosphoserine202 def: "Protein AKTS1_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q96B36] xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065584 name: AKTS1_HUMAN-Phosphoserine203 def: "Protein AKTS1_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q96B36] xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065585 name: AKTS1_HUMAN-Phosphoserine211 def: "Protein AKTS1_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:Q96B36] xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065586 name: AKTS1_HUMAN-Phosphoserine212 def: "Protein AKTS1_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q96B36] xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065587 name: AKTS1_HUMAN-Phosphothreonine246 def: "Protein AKTS1_HUMAN with the residue 246 substituted with Phosphothreonine" [UniProtKB:Q96B36] comment: by PKB/AKT1; xref: UniProtKB:Q96B36 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:B0065588 name: ALBU_HUMAN-Phosphoserine82 def: "Protein ALBU_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:P02768] xref: UniProtKB:P02768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054874 ! ALBU_HUMAN [Term] id: CCO:B0065589 name: ALBU_HUMAN-Phosphotyrosine108 def: "Protein ALBU_HUMAN with the residue 108 substituted with Phosphotyrosine" [UniProtKB:P02768] xref: UniProtKB:P02768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054874 ! ALBU_HUMAN [Term] id: CCO:B0065590 name: ALBU_HUMAN-Phosphotyrosine164 def: "Protein ALBU_HUMAN with the residue 164 substituted with Phosphotyrosine" [UniProtKB:P02768] xref: UniProtKB:P02768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054874 ! ALBU_HUMAN [Term] id: CCO:B0065591 name: ALDH2_HUMAN-N6-acetyllysine368 def: "Protein ALDH2_HUMAN with the residue 368 substituted with N6-acetyllysine" [UniProtKB:P05091] comment: By similarity xref: UniProtKB:P05091 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063375 ! ALDH2_HUMAN [Term] id: CCO:B0065592 name: ALDOA_HUMAN-Phosphotyrosine3 def: "Protein ALDOA_HUMAN with the residue 3 substituted with Phosphotyrosine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065593 name: ALDOA_HUMAN-Phosphotyrosine5 def: "Protein ALDOA_HUMAN with the residue 5 substituted with Phosphotyrosine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065594 name: ALDOA_HUMAN-N6-acetyllysine13 def: "Protein ALDOA_HUMAN with the residue 13 substituted with N6-acetyllysine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065595 name: ALDOA_HUMAN-Phosphoserine36 def: "Protein ALDOA_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P04075] comment: By similarity xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065596 name: ALDOA_HUMAN-Phosphoserine39 def: "Protein ALDOA_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:P04075] comment: By similarity xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065597 name: ALDOA_HUMAN-N6-acetyllysine42 def: "Protein ALDOA_HUMAN with the residue 42 substituted with N6-acetyllysine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065598 name: ALDOA_HUMAN-Phosphoserine46 def: "Protein ALDOA_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065599 name: ALDOA_HUMAN-Phosphothreonine65 def: "Protein ALDOA_HUMAN with the residue 65 substituted with Phosphothreonine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000751 ! fructose-bisphosphate aldolase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065600 name: ALDOA_HUMAN-Phosphotyrosine204 def: "Protein ALDOA_HUMAN with the residue 204 substituted with Phosphotyrosine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065601 name: ALDOA_HUMAN-Phosphotyrosine223 def: "Protein ALDOA_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065602 name: ALDOA_HUMAN-Phosphothreonine235 def: "Protein ALDOA_HUMAN with the residue 235 substituted with Phosphothreonine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065603 name: ALDOA_HUMAN-Phosphothreonine241 def: "Protein ALDOA_HUMAN with the residue 241 substituted with Phosphothreonine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065604 name: ALDOA_HUMAN-Phosphoserine354 def: "Protein ALDOA_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065605 name: ALDOA_HUMAN-Phosphoserine356 def: "Protein ALDOA_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:P04075] xref: UniProtKB:P04075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063178 ! ALDOA_HUMAN [Term] id: CCO:B0065606 name: ALK_HUMAN-Phosphotyrosine1283 def: "Protein ALK_HUMAN with the residue 1283 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0065607 name: ALK_HUMAN-Phosphotyrosine1359 def: "Protein ALK_HUMAN with the residue 1359 substituted with Phosphotyrosine" [UniProtKB:Q9UM73] xref: UniProtKB:Q9UM73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:B0065608 name: ALS2_HUMAN-Phosphoserine483 def: "Protein ALS2_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:Q96Q42] xref: UniProtKB:Q96Q42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058350 ! ALS2_HUMAN [Term] id: CCO:B0065609 name: ALS2_HUMAN-Phosphoserine492 def: "Protein ALS2_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q96Q42] xref: UniProtKB:Q96Q42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058350 ! ALS2_HUMAN [Term] id: CCO:B0065610 name: ALS2_HUMAN-Phosphothreonine1344 def: "Protein ALS2_HUMAN with the residue 1344 substituted with Phosphothreonine" [UniProtKB:Q96Q42] xref: UniProtKB:Q96Q42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001392 ! Ran guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003575 ! Rab guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0003592 ! Rab GTPase binding relationship: has_function CCO:F0004518 ! Rac guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005870 ! protein serine/threonine kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000740 ! postsynaptic density relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001663 ! vesicular fraction relationship: located_in CCO:C0001729 ! dendritic spine relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0058350 ! ALS2_HUMAN [Term] id: CCO:B0065611 name: ALS2_HUMAN-Phosphoserine1464 def: "Protein ALS2_HUMAN with the residue 1464 substituted with Phosphoserine" [UniProtKB:Q96Q42] xref: UniProtKB:Q96Q42 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058350 ! ALS2_HUMAN [Term] id: CCO:B0065612 name: AMFR1_HUMAN-Phosphoserine194 def: "Protein AMFR1_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:P26442] comment: Potential xref: UniProtKB:P26442 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055191 ! AMFR1_HUMAN [Term] id: CCO:B0065613 name: AMFR2_HUMAN-Phosphoserine516 def: "Protein AMFR2_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q9UKV5] xref: UniProtKB:Q9UKV5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059206 ! AMFR2_HUMAN [Term] id: CCO:B0065614 name: AMFR2_HUMAN-Phosphoserine523 def: "Protein AMFR2_HUMAN with the residue 523 substituted with Phosphoserine" [UniProtKB:Q9UKV5] xref: UniProtKB:Q9UKV5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059206 ! AMFR2_HUMAN [Term] id: CCO:B0065615 name: AMFR2_HUMAN-Phosphoserine542 def: "Protein AMFR2_HUMAN with the residue 542 substituted with Phosphoserine" [UniProtKB:Q9UKV5] xref: UniProtKB:Q9UKV5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059206 ! AMFR2_HUMAN [Term] id: CCO:B0065616 name: AMGO1_HUMAN-Phosphoserine477 def: "Protein AMGO1_HUMAN with the residue 477 substituted with Phosphoserine" [UniProtKB:Q86WK6] xref: UniProtKB:Q86WK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057275 ! AMGO1_HUMAN [Term] id: CCO:B0065617 name: AMOT_HUMAN-Phosphoserine305 def: "Protein AMOT_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q4VCS5] xref: UniProtKB:Q4VCS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056332 ! AMOT_HUMAN [Term] id: CCO:B0065618 name: AMOT_HUMAN-Phosphoserine312 def: "Protein AMOT_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q4VCS5] xref: UniProtKB:Q4VCS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005868 ! angiostatin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0056332 ! AMOT_HUMAN [Term] id: CCO:B0065619 name: AMOT_HUMAN-Phosphoserine712 def: "Protein AMOT_HUMAN with the residue 712 substituted with Phosphoserine" [UniProtKB:Q4VCS5] comment: By similarity xref: UniProtKB:Q4VCS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056332 ! AMOT_HUMAN [Term] id: CCO:B0065620 name: AMOT_HUMAN-Phosphothreonine1061 def: "Protein AMOT_HUMAN with the residue 1061 substituted with Phosphothreonine" [UniProtKB:Q4VCS5] xref: UniProtKB:Q4VCS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056332 ! AMOT_HUMAN [Term] id: CCO:B0065621 name: AMPE_HUMAN-Phosphotyrosine12 def: "Protein AMPE_HUMAN with the residue 12 substituted with Phosphotyrosine" [UniProtKB:Q07075] comment: By similarity xref: UniProtKB:Q07075 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055781 ! AMPE_HUMAN [Term] id: CCO:B0065622 name: AN32A_HUMAN-Phosphothreonine15 def: "Protein AN32A_HUMAN with the residue 15 substituted with Phosphothreonine" [UniProtKB:P39687] xref: UniProtKB:P39687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006073 ! AN32A_HUMAN [Term] id: CCO:B0065623 name: AN32A_HUMAN-Phosphoserine17 def: "Protein AN32A_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:P39687] xref: UniProtKB:P39687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006073 ! AN32A_HUMAN [Term] id: CCO:B0065624 name: ANC2_HUMAN-Phosphoserine470 def: "Protein ANC2_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:Q9UJX6] xref: UniProtKB:Q9UJX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002216 ! ANC2_HUMAN [Term] id: CCO:B0065625 name: ANGT_HUMAN-aspartate34 def: "Protein ANGT_HUMAN with the residue 34 substituted with aspartate" [UniProtKB:P01019] comment: in form angiotensin-A; xref: UniProtKB:P01019 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032938 ! ANGT_HUMAN [Term] id: CCO:B0065626 name: ANK3_HUMAN-Phosphotyrosine533 def: "Protein ANK3_HUMAN with the residue 533 substituted with Phosphotyrosine" [UniProtKB:Q12955] xref: UniProtKB:Q12955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041526 ! ANK3_HUMAN [Term] id: CCO:B0065627 name: ANK3_HUMAN-Phosphoserine1459 def: "Protein ANK3_HUMAN with the residue 1459 substituted with Phosphoserine" [UniProtKB:Q12955] xref: UniProtKB:Q12955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041526 ! ANK3_HUMAN [Term] id: CCO:B0065628 name: ANLN_HUMAN-Phosphoserine54 def: "Protein ANLN_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065629 name: ANLN_HUMAN-Phosphoserine72 def: "Protein ANLN_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065630 name: ANLN_HUMAN-Phosphoserine172 def: "Protein ANLN_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065631 name: ANLN_HUMAN-Phosphothreonine364 def: "Protein ANLN_HUMAN with the residue 364 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065632 name: ANLN_HUMAN-Phosphothreonine393 def: "Protein ANLN_HUMAN with the residue 393 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065633 name: ANLN_HUMAN-Phosphothreonine397 def: "Protein ANLN_HUMAN with the residue 397 substituted with Phosphothreonine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065634 name: ANLN_HUMAN-Phosphoserine518 def: "Protein ANLN_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065635 name: ANLN_HUMAN-Phosphoserine553 def: "Protein ANLN_HUMAN with the residue 553 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065636 name: ANLN_HUMAN-Phosphoserine658 def: "Protein ANLN_HUMAN with the residue 658 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065637 name: ANLN_HUMAN-Phosphoserine664 def: "Protein ANLN_HUMAN with the residue 664 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065638 name: ANLN_HUMAN-Phosphoserine792 def: "Protein ANLN_HUMAN with the residue 792 substituted with Phosphoserine" [UniProtKB:Q9NQW6] xref: UniProtKB:Q9NQW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002155 ! ANLN_HUMAN [Term] id: CCO:B0065639 name: ANM1_HUMAN-Phosphotyrosine299 def: "Protein ANM1_HUMAN with the residue 299 substituted with Phosphotyrosine" [UniProtKB:Q99873] xref: UniProtKB:Q99873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005713 ! ANM1_HUMAN [Term] id: CCO:B0065640 name: ANPRC_HUMAN-Phosphoserine533 def: "Protein ANPRC_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:P17342] xref: UniProtKB:P17342 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055086 ! ANPRC_HUMAN [Term] id: CCO:B0065641 name: ANR17_HUMAN-Phosphotyrosine1333 def: "Protein ANR17_HUMAN with the residue 1333 substituted with Phosphotyrosine" [UniProtKB:O75179] xref: UniProtKB:O75179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054612 ! ANR17_HUMAN [Term] id: CCO:B0065642 name: ANR17_HUMAN-Phosphoserine2042 def: "Protein ANR17_HUMAN with the residue 2042 substituted with Phosphoserine" [UniProtKB:O75179] xref: UniProtKB:O75179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054612 ! ANR17_HUMAN [Term] id: CCO:B0065643 name: ANR17_HUMAN-Phosphoserine2045 def: "Protein ANR17_HUMAN with the residue 2045 substituted with Phosphoserine" [UniProtKB:O75179] xref: UniProtKB:O75179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054612 ! ANR17_HUMAN [Term] id: CCO:B0065644 name: ANR17_HUMAN-Phosphoserine2047 def: "Protein ANR17_HUMAN with the residue 2047 substituted with Phosphoserine" [UniProtKB:O75179] xref: UniProtKB:O75179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054612 ! ANR17_HUMAN [Term] id: CCO:B0065645 name: ANR17_HUMAN-Phosphoserine2059 def: "Protein ANR17_HUMAN with the residue 2059 substituted with Phosphoserine" [UniProtKB:O75179] xref: UniProtKB:O75179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054612 ! ANR17_HUMAN [Term] id: CCO:B0065646 name: ANR17_HUMAN-Phosphoserine2067 def: "Protein ANR17_HUMAN with the residue 2067 substituted with Phosphoserine" [UniProtKB:O75179] xref: UniProtKB:O75179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054612 ! ANR17_HUMAN [Term] id: CCO:B0065647 name: ANTR1_HUMAN-Phosphoserine362 def: "Protein ANTR1_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q9H6X2] xref: UniProtKB:Q9H6X2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063006 ! ANTR1_HUMAN [Term] id: CCO:B0065648 name: ANTR1_HUMAN-Phosphotyrosine425 def: "Protein ANTR1_HUMAN with the residue 425 substituted with Phosphotyrosine" [UniProtKB:Q9H6X2] xref: UniProtKB:Q9H6X2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063006 ! ANTR1_HUMAN [Term] id: CCO:B0065649 name: ANXA1_HUMAN-Phosphotyrosine39 def: "Protein ANXA1_HUMAN with the residue 39 substituted with Phosphotyrosine" [UniProtKB:P04083] xref: UniProtKB:P04083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001479 ! ANXA1_HUMAN [Term] id: CCO:B0065650 name: ANXA2_HUMAN-Phosphotyrosine199 def: "Protein ANXA2_HUMAN with the residue 199 substituted with Phosphotyrosine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0065651 name: ANXA2_HUMAN-Phosphotyrosine238 def: "Protein ANXA2_HUMAN with the residue 238 substituted with Phosphotyrosine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0065652 name: ANXA2_HUMAN-Phosphotyrosine316 def: "Protein ANXA2_HUMAN with the residue 316 substituted with Phosphotyrosine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0065653 name: ANXA2_HUMAN-Phosphotyrosine317 def: "Protein ANXA2_HUMAN with the residue 317 substituted with Phosphotyrosine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0065654 name: ANXA2_HUMAN-Phosphotyrosine318 def: "Protein ANXA2_HUMAN with the residue 318 substituted with Phosphotyrosine" [UniProtKB:P07355] xref: UniProtKB:P07355 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005736 ! ANXA2_HUMAN [Term] id: CCO:B0065655 name: ANXA5_HUMAN-Phosphotyrosine94 def: "Protein ANXA5_HUMAN with the residue 94 substituted with Phosphotyrosine" [UniProtKB:P08758] xref: UniProtKB:P08758 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001215 ! phospholipase inhibitor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0015822 ! ANXA5_HUMAN [Term] id: CCO:B0065656 name: AP1B1_HUMAN-Phosphotyrosine897 def: "Protein AP1B1_HUMAN with the residue 897 substituted with Phosphotyrosine" [UniProtKB:Q10567] xref: UniProtKB:Q10567 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063204 ! AP1B1_HUMAN [Term] id: CCO:B0065657 name: AP1M1_HUMAN-N-acetylserine2 def: "Protein AP1M1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9BXS5] xref: UniProtKB:Q9BXS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062862 ! AP1M1_HUMAN [Term] id: CCO:B0065658 name: AP1M1_HUMAN-Phosphothreonine152 def: "Protein AP1M1_HUMAN with the residue 152 substituted with Phosphothreonine" [UniProtKB:Q9BXS5] comment: By similarity xref: UniProtKB:Q9BXS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0062862 ! AP1M1_HUMAN [Term] id: CCO:B0065659 name: AP1M1_HUMAN-Phosphothreonine154 def: "Protein AP1M1_HUMAN with the residue 154 substituted with Phosphothreonine" [UniProtKB:Q9BXS5] comment: By similarity xref: UniProtKB:Q9BXS5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062862 ! AP1M1_HUMAN [Term] id: CCO:B0065660 name: AP2A1_HUMAN-Phosphothreonine650 def: "Protein AP2A1_HUMAN with the residue 650 substituted with Phosphothreonine" [UniProtKB:O95782] comment: By similarity xref: UniProtKB:O95782 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063354 ! AP2A1_HUMAN [Term] id: CCO:B0065661 name: AP2A1_HUMAN-Phosphoserine652 def: "Protein AP2A1_HUMAN with the residue 652 substituted with Phosphoserine" [UniProtKB:O95782] comment: By similarity xref: UniProtKB:O95782 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063354 ! AP2A1_HUMAN [Term] id: CCO:B0065662 name: AP2A1_HUMAN-Phosphothreonine653 def: "Protein AP2A1_HUMAN with the residue 653 substituted with Phosphothreonine" [UniProtKB:O95782] comment: By similarity xref: UniProtKB:O95782 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0000967 ! AP-2 adaptor complex relationship: located_in CCO:C0000975 ! clathrin coat of trans-Golgi network vesicle relationship: located_in CCO:C0000976 ! clathrin adaptor complex relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0063354 ! AP2A1_HUMAN [Term] id: CCO:B0065663 name: AP2A1_HUMAN-Phosphoserine655 def: "Protein AP2A1_HUMAN with the residue 655 substituted with Phosphoserine" [UniProtKB:O95782] comment: By similarity xref: UniProtKB:O95782 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063354 ! AP2A1_HUMAN [Term] id: CCO:B0065664 name: AP2C_HUMAN-Phosphoserine434 def: "Protein AP2C_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:Q92754] xref: UniProtKB:Q92754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005377 ! AP2C_HUMAN [Term] id: CCO:B0065665 name: AP2M1_HUMAN-Phosphothreonine156 def: "Protein AP2M1_HUMAN with the residue 156 substituted with Phosphothreonine" [UniProtKB:Q96CW1] comment: By similarity xref: UniProtKB:Q96CW1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062824 ! AP2M1_HUMAN [Term] id: CCO:B0065666 name: AP3B1_HUMAN-Phosphoserine276 def: "Protein AP3B1_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:O00203] xref: UniProtKB:O00203 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054299 ! AP3B1_HUMAN [Term] id: CCO:B0065667 name: AP3B1_HUMAN-Phosphoserine609 def: "Protein AP3B1_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:O00203] xref: UniProtKB:O00203 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0054299 ! AP3B1_HUMAN [Term] id: CCO:B0065668 name: AP3D1_HUMAN-Phosphoserine632 def: "Protein AP3D1_HUMAN with the residue 632 substituted with Phosphoserine" [UniProtKB:O14617] xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065669 name: AP3D1_HUMAN-Phosphoserine634 def: "Protein AP3D1_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:O14617] xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065670 name: AP3D1_HUMAN-Phosphoserine636 def: "Protein AP3D1_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:O14617] xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065671 name: AP3D1_HUMAN-Phosphoserine658 def: "Protein AP3D1_HUMAN with the residue 658 substituted with Phosphoserine" [UniProtKB:O14617] xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065672 name: AP3D1_HUMAN-Phosphoserine759 def: "Protein AP3D1_HUMAN with the residue 759 substituted with Phosphoserine" [UniProtKB:O14617] comment: By similarity xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000962 ! membrane coat relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065673 name: AP3D1_HUMAN-Phosphothreonine762 def: "Protein AP3D1_HUMAN with the residue 762 substituted with Phosphothreonine" [UniProtKB:O14617] comment: By similarity xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065674 name: AP3D1_HUMAN-Phosphoserine764 def: "Protein AP3D1_HUMAN with the residue 764 substituted with Phosphoserine" [UniProtKB:O14617] comment: By similarity xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065675 name: AP3D1_HUMAN-Phosphoserine788 def: "Protein AP3D1_HUMAN with the residue 788 substituted with Phosphoserine" [UniProtKB:O14617] comment: By similarity xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065676 name: AP3D1_HUMAN-Phosphoserine829 def: "Protein AP3D1_HUMAN with the residue 829 substituted with Phosphoserine" [UniProtKB:O14617] xref: UniProtKB:O14617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:B0065677 name: AP4A_HUMAN-N-acetylalanine2 def: "Protein AP4A_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P50583] xref: UniProtKB:P50583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055454 ! AP4A_HUMAN [Term] id: CCO:B0065678 name: APAF_HUMAN-Phosphothreonine204 def: "Protein APAF_HUMAN with the residue 204 substituted with Phosphothreonine" [UniProtKB:O14727] xref: UniProtKB:O14727 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054371 ! APAF_HUMAN [Term] id: CCO:B0065679 name: APAF_HUMAN-Phosphoserine238 def: "Protein APAF_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:O14727] xref: UniProtKB:O14727 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054371 ! APAF_HUMAN [Term] id: CCO:B0065680 name: APAF_HUMAN-Phosphoserine248 def: "Protein APAF_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:O14727] xref: UniProtKB:O14727 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054371 ! APAF_HUMAN [Term] id: CCO:B0065681 name: APBA3_HUMAN-Phosphoserine372 def: "Protein APBA3_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:O96018] xref: UniProtKB:O96018 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0016816 ! APBA3_HUMAN [Term] id: CCO:B0065682 name: APC1_HUMAN-Phosphoserine51 def: "Protein APC1_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0065683 name: APC1_HUMAN-Phosphoserine60 def: "Protein APC1_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0065684 name: APC1_HUMAN-Phosphothreonine65 def: "Protein APC1_HUMAN with the residue 65 substituted with Phosphothreonine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0065685 name: APC1_HUMAN-Phosphoserine341 def: "Protein APC1_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0065686 name: APC1_HUMAN-Phosphoserine547 def: "Protein APC1_HUMAN with the residue 547 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0065687 name: APC1_HUMAN-Phosphoserine563 def: "Protein APC1_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:Q9H1A4] xref: UniProtKB:Q9H1A4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002125 ! APC1_HUMAN [Term] id: CCO:B0065688 name: APC4_HUMAN-Phosphoserine777 def: "Protein APC4_HUMAN with the residue 777 substituted with Phosphoserine" [UniProtKB:Q9UJX5] xref: UniProtKB:Q9UJX5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002215 ! APC4_HUMAN [Term] id: CCO:B0065689 name: APEL_HUMAN-Pyrrolidone carboxylic acid65 def: "Protein APEL_HUMAN with the residue 65 substituted with Pyrrolidone carboxylic acid" [UniProtKB:Q9ULZ1] comment: By similarity xref: UniProtKB:Q9ULZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0059238 ! APEL_HUMAN [Term] id: CCO:B0065690 name: APEX1_HUMAN-Phosphotyrosine262 def: "Protein APEX1_HUMAN with the residue 262 substituted with Phosphotyrosine" [UniProtKB:P27695] xref: UniProtKB:P27695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055194 ! APEX1_HUMAN [Term] id: CCO:B0065691 name: API5_HUMAN-Phosphoserine464 def: "Protein API5_HUMAN with the residue 464 substituted with Phosphoserine" [UniProtKB:Q9BZZ5] xref: UniProtKB:Q9BZZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058612 ! API5_HUMAN [Term] id: CCO:B0065692 name: APLP2_HUMAN-Phosphotyrosine750 def: "Protein APLP2_HUMAN with the residue 750 substituted with Phosphotyrosine" [UniProtKB:Q06481] xref: UniProtKB:Q06481 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005374 ! APLP2_HUMAN [Term] id: CCO:B0065693 name: APLP2_HUMAN-Phosphotyrosine755 def: "Protein APLP2_HUMAN with the residue 755 substituted with Phosphotyrosine" [UniProtKB:Q06481] xref: UniProtKB:Q06481 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005374 ! APLP2_HUMAN [Term] id: CCO:B0065694 name: APOA2_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein APOA2_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P02652] xref: UniProtKB:P02652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054863 ! APOA2_HUMAN [Term] id: CCO:B0065695 name: AR2BP_HUMAN-Phosphoserine157 def: "Protein AR2BP_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:Q9Y2Y0] xref: UniProtKB:Q9Y2Y0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000341 ! mitochondrial intermembrane space relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0059322 ! AR2BP_HUMAN [Term] id: CCO:B0065696 name: ARBK1_HUMAN-Phosphoserine670 def: "Protein ARBK1_HUMAN with the residue 670 substituted with Phosphoserine" [UniProtKB:P25098] xref: UniProtKB:P25098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055180 ! ARBK1_HUMAN [Term] id: CCO:B0065697 name: ARD1A_HUMAN-Phosphoserine205 def: "Protein ARD1A_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:P41227] xref: UniProtKB:P41227 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005243 ! ARD1A_HUMAN [Term] id: CCO:B0065698 name: ARF1_HUMAN-Phosphoserine147 def: "Protein ARF1_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:P84077] xref: UniProtKB:P84077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015288 ! ARF1_HUMAN [Term] id: CCO:B0065699 name: ARFG1_HUMAN-Phosphoserine304 def: "Protein ARFG1_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q8N6T3] xref: UniProtKB:Q8N6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:B0065700 name: ARFG2_HUMAN-Phosphoserine146 def: "Protein ARFG2_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q8N6H7] xref: UniProtKB:Q8N6H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057489 ! ARFG2_HUMAN [Term] id: CCO:B0065701 name: ARFG2_HUMAN-Phosphoserine337 def: "Protein ARFG2_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q8N6H7] comment: By similarity xref: UniProtKB:Q8N6H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057489 ! ARFG2_HUMAN [Term] id: CCO:B0065702 name: ARFG2_HUMAN-Phosphoserine368 def: "Protein ARFG2_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q8N6H7] xref: UniProtKB:Q8N6H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057489 ! ARFG2_HUMAN [Term] id: CCO:B0065703 name: ARFG2_HUMAN-Phosphoserine432 def: "Protein ARFG2_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:Q8N6H7] xref: UniProtKB:Q8N6H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057489 ! ARFG2_HUMAN [Term] id: CCO:B0065704 name: ARFG2_HUMAN-Phosphoserine498 def: "Protein ARFG2_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:Q8N6H7] xref: UniProtKB:Q8N6H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057489 ! ARFG2_HUMAN [Term] id: CCO:B0065705 name: ARFG3_HUMAN-Phosphoserine143 def: "Protein ARFG3_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q9NP61] xref: UniProtKB:Q9NP61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058833 ! ARFG3_HUMAN [Term] id: CCO:B0065706 name: ARFG3_HUMAN-Phosphoserine270 def: "Protein ARFG3_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q9NP61] xref: UniProtKB:Q9NP61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058833 ! ARFG3_HUMAN [Term] id: CCO:B0065707 name: ARFG3_HUMAN-Phosphoserine331 def: "Protein ARFG3_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q9NP61] xref: UniProtKB:Q9NP61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058833 ! ARFG3_HUMAN [Term] id: CCO:B0065708 name: ARFG3_HUMAN-Phosphoserine453 def: "Protein ARFG3_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q9NP61] xref: UniProtKB:Q9NP61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058833 ! ARFG3_HUMAN [Term] id: CCO:B0065709 name: ARGAL_HUMAN-Phosphotyrosine131 def: "Protein ARGAL_HUMAN with the residue 131 substituted with Phosphotyrosine" [UniProtKB:Q9HCE6] xref: UniProtKB:Q9HCE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058804 ! ARGAL_HUMAN [Term] id: CCO:B0065710 name: ARGAL_HUMAN-Phosphotyrosine152 def: "Protein ARGAL_HUMAN with the residue 152 substituted with Phosphotyrosine" [UniProtKB:Q9HCE6] comment: By similarity xref: UniProtKB:Q9HCE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058804 ! ARGAL_HUMAN [Term] id: CCO:B0065711 name: ARHG1_HUMAN-Phosphoserine863 def: "Protein ARHG1_HUMAN with the residue 863 substituted with Phosphoserine" [UniProtKB:Q92888] xref: UniProtKB:Q92888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002023 ! ARHG1_HUMAN [Term] id: CCO:B0065712 name: ARHG2_HUMAN-Phosphoserine143 def: "Protein ARHG2_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q92974] comment: by PAK4; xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065713 name: ARHG2_HUMAN-Phosphoserine149 def: "Protein ARHG2_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065714 name: ARHG2_HUMAN-Phosphothreonine152 def: "Protein ARHG2_HUMAN with the residue 152 substituted with Phosphothreonine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065715 name: ARHG2_HUMAN-Phosphothreonine153 def: "Protein ARHG2_HUMAN with the residue 153 substituted with Phosphothreonine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065716 name: ARHG2_HUMAN-Phosphoserine163 def: "Protein ARHG2_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065717 name: ARHG2_HUMAN-Phosphoserine645 def: "Protein ARHG2_HUMAN with the residue 645 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065718 name: ARHG2_HUMAN-Phosphoserine648 def: "Protein ARHG2_HUMAN with the residue 648 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065719 name: ARHG2_HUMAN-Phosphothreonine679 def: "Protein ARHG2_HUMAN with the residue 679 substituted with Phosphothreonine" [UniProtKB:Q92974] comment: by MAPK1 or MAPK3; xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065720 name: ARHG2_HUMAN-Phosphoserine696 def: "Protein ARHG2_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065721 name: ARHG2_HUMAN-Phosphoserine886 def: "Protein ARHG2_HUMAN with the residue 886 substituted with Phosphoserine" [UniProtKB:Q92974] comment: by PAK1 and STK6; xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065722 name: ARHG2_HUMAN-Phosphotyrosine894 def: "Protein ARHG2_HUMAN with the residue 894 substituted with Phosphotyrosine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065723 name: ARHG2_HUMAN-Phosphoserine896 def: "Protein ARHG2_HUMAN with the residue 896 substituted with Phosphoserine" [UniProtKB:Q92974] comment: by PAK4; xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065724 name: ARHG2_HUMAN-Phosphoserine932 def: "Protein ARHG2_HUMAN with the residue 932 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065725 name: ARHG2_HUMAN-Phosphoserine940 def: "Protein ARHG2_HUMAN with the residue 940 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065726 name: ARHG2_HUMAN-Phosphoserine941 def: "Protein ARHG2_HUMAN with the residue 941 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065727 name: ARHG2_HUMAN-Phosphoserine956 def: "Protein ARHG2_HUMAN with the residue 956 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065728 name: ARHG2_HUMAN-Phosphoserine960 def: "Protein ARHG2_HUMAN with the residue 960 substituted with Phosphoserine" [UniProtKB:Q92974] xref: UniProtKB:Q92974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:B0065729 name: ARHG5_HUMAN-Phosphoserine11 def: "Protein ARHG5_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065730 name: ARHG5_HUMAN-Phosphoserine184 def: "Protein ARHG5_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065731 name: ARHG5_HUMAN-Phosphoserine445 def: "Protein ARHG5_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065732 name: ARHG5_HUMAN-Phosphoserine450 def: "Protein ARHG5_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065733 name: ARHG5_HUMAN-Phosphotyrosine1097 def: "Protein ARHG5_HUMAN with the residue 1097 substituted with Phosphotyrosine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065734 name: ARHG5_HUMAN-Phosphotyrosine1100 def: "Protein ARHG5_HUMAN with the residue 1100 substituted with Phosphotyrosine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065735 name: ARHG5_HUMAN-Phosphoserine1126 def: "Protein ARHG5_HUMAN with the residue 1126 substituted with Phosphoserine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065736 name: ARHG5_HUMAN-Phosphotyrosine1370 def: "Protein ARHG5_HUMAN with the residue 1370 substituted with Phosphotyrosine" [UniProtKB:Q12774] xref: UniProtKB:Q12774 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:B0065737 name: ARHG6_HUMAN-Phosphoserine122 def: "Protein ARHG6_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q15052] comment: By similarity xref: UniProtKB:Q15052 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056039 ! ARHG6_HUMAN [Term] id: CCO:B0065738 name: ARHG6_HUMAN-Phosphoserine225 def: "Protein ARHG6_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q15052] xref: UniProtKB:Q15052 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056039 ! ARHG6_HUMAN [Term] id: CCO:B0065739 name: ARHG6_HUMAN-Phosphoserine488 def: "Protein ARHG6_HUMAN with the residue 488 substituted with Phosphoserine" [UniProtKB:Q15052] xref: UniProtKB:Q15052 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056039 ! ARHG6_HUMAN [Term] id: CCO:B0065740 name: ARHG6_HUMAN-Phosphoserine640 def: "Protein ARHG6_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q15052] comment: By similarity xref: UniProtKB:Q15052 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0056039 ! ARHG6_HUMAN [Term] id: CCO:B0065741 name: ARHG6_HUMAN-Phosphothreonine650 def: "Protein ARHG6_HUMAN with the residue 650 substituted with Phosphothreonine" [UniProtKB:Q15052] comment: By similarity xref: UniProtKB:Q15052 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056039 ! ARHG6_HUMAN [Term] id: CCO:B0065742 name: ARHG6_HUMAN-Phosphoserine684 def: "Protein ARHG6_HUMAN with the residue 684 substituted with Phosphoserine" [UniProtKB:Q15052] xref: UniProtKB:Q15052 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056039 ! ARHG6_HUMAN [Term] id: CCO:B0065743 name: ARHG7_HUMAN-Phosphoserine176 def: "Protein ARHG7_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q14155] comment: By similarity xref: UniProtKB:Q14155 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055966 ! ARHG7_HUMAN [Term] id: CCO:B0065744 name: ARHG7_HUMAN-Phosphoserine249 def: "Protein ARHG7_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q14155] xref: UniProtKB:Q14155 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055966 ! ARHG7_HUMAN [Term] id: CCO:B0065745 name: ARIP4_HUMAN-Phosphoserine187 def: "Protein ARIP4_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:Q9Y4B4] xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:B0065746 name: ARIP4_HUMAN-Phosphoserine188 def: "Protein ARIP4_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:Q9Y4B4] xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:B0065747 name: ARIP4_HUMAN-Phosphoserine189 def: "Protein ARIP4_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q9Y4B4] xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:B0065748 name: ARIP4_HUMAN-Phosphoserine191 def: "Protein ARIP4_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q9Y4B4] xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:B0065749 name: ARIP4_HUMAN-Phosphoserine1138 def: "Protein ARIP4_HUMAN with the residue 1138 substituted with Phosphoserine" [UniProtKB:Q9Y4B4] xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:B0065750 name: ARIP4_HUMAN-Phosphoserine1169 def: "Protein ARIP4_HUMAN with the residue 1169 substituted with Phosphoserine" [UniProtKB:Q9Y4B4] xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:B0065751 name: ARIP4_HUMAN-Phosphoserine1172 def: "Protein ARIP4_HUMAN with the residue 1172 substituted with Phosphoserine" [UniProtKB:Q9Y4B4] xref: UniProtKB:Q9Y4B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:B0065752 name: ARPC4_HUMAN-N-acetylthreonine2 def: "Protein ARPC4_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P59998] xref: UniProtKB:P59998 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063364 ! ARPC4_HUMAN [Term] id: CCO:B0065753 name: ARS2_HUMAN-Phosphoserine136 def: "Protein ARS2_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q9BXP5] xref: UniProtKB:Q9BXP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:B0065754 name: ASSY_HUMAN-Phosphoserine352 def: "Protein ASSY_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:P00966] xref: UniProtKB:P00966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063252 ! ASSY_HUMAN [Term] id: CCO:B0065755 name: AT2A3_HUMAN-N-acetylmethionine1 def: "Protein AT2A3_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q93084] xref: UniProtKB:Q93084 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063203 ! AT2A3_HUMAN [Term] id: CCO:B0065756 name: ATD3A_HUMAN-N-acetylserine2 def: "Protein ATD3A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9NVI7] xref: UniProtKB:Q9NVI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063202 ! ATD3A_HUMAN [Term] id: CCO:B0065757 name: ATD3A_HUMAN-N6-acetyllysine539 def: "Protein ATD3A_HUMAN with the residue 539 substituted with N6-acetyllysine" [UniProtKB:Q9NVI7] comment: By similarity xref: UniProtKB:Q9NVI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063202 ! ATD3A_HUMAN [Term] id: CCO:B0065758 name: ATPK_HUMAN-N-acetylalanine2 def: "Protein ATPK_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P56134] comment: By similarity xref: UniProtKB:P56134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000337 ! mitochondrial proton-transporting ATP synthase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001924 ! proton-transporting ATP synthase complex, coupling factor F(o) relationship: transformation_of CCO:B0063395 ! ATPK_HUMAN [Term] id: CCO:B0065759 name: ATPO_HUMAN-N6-acetyllysine60 def: "Protein ATPO_HUMAN with the residue 60 substituted with N6-acetyllysine" [UniProtKB:P48047] comment: By similarity xref: UniProtKB:P48047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:B0065760 name: ATPO_HUMAN-N6-acetyllysine70 def: "Protein ATPO_HUMAN with the residue 70 substituted with N6-acetyllysine" [UniProtKB:P48047] comment: By similarity xref: UniProtKB:P48047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:B0065761 name: ATPO_HUMAN-N6-acetyllysine158 def: "Protein ATPO_HUMAN with the residue 158 substituted with N6-acetyllysine" [UniProtKB:P48047] comment: By similarity xref: UniProtKB:P48047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:B0065762 name: ATPO_HUMAN-N6-acetyllysine162 def: "Protein ATPO_HUMAN with the residue 162 substituted with N6-acetyllysine" [UniProtKB:P48047] comment: By similarity xref: UniProtKB:P48047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:B0065763 name: ATPO_HUMAN-N6-acetyllysine172 def: "Protein ATPO_HUMAN with the residue 172 substituted with N6-acetyllysine" [UniProtKB:P48047] comment: By similarity xref: UniProtKB:P48047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:B0065764 name: ATPO_HUMAN-N6-acetyllysine176 def: "Protein ATPO_HUMAN with the residue 176 substituted with N6-acetyllysine" [UniProtKB:P48047] comment: By similarity xref: UniProtKB:P48047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001746 ! drug binding relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006277 ! hydrogen ion transporting ATP synthase activity, rotational mechanism relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000337 ! mitochondrial proton-transporting ATP synthase complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: transformation_of CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:B0065765 name: ATPO_HUMAN-N6-acetyllysine192 def: "Protein ATPO_HUMAN with the residue 192 substituted with N6-acetyllysine" [UniProtKB:P48047] comment: By similarity xref: UniProtKB:P48047 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:B0065766 name: ATX2L_HUMAN-N-acetylmethionine1 def: "Protein ATX2L_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065767 name: ATX2L_HUMAN-Phosphoserine111 def: "Protein ATX2L_HUMAN with the residue 111 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065768 name: ATX2L_HUMAN-Phosphotyrosine264 def: "Protein ATX2L_HUMAN with the residue 264 substituted with Phosphotyrosine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065769 name: ATX2L_HUMAN-Phosphotyrosine309 def: "Protein ATX2L_HUMAN with the residue 309 substituted with Phosphotyrosine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065770 name: ATX2L_HUMAN-Phosphoserine335 def: "Protein ATX2L_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065771 name: ATX2L_HUMAN-Phosphoserine339 def: "Protein ATX2L_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065772 name: ATX2L_HUMAN-Phosphoserine341 def: "Protein ATX2L_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065773 name: ATX2L_HUMAN-Phosphotyrosine349 def: "Protein ATX2L_HUMAN with the residue 349 substituted with Phosphotyrosine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065774 name: ATX2L_HUMAN-Omega-N-methylated arginine361 def: "Protein ATX2L_HUMAN with the residue 361 substituted with Omega-N-methylated arginine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065775 name: ATX2L_HUMAN-Phosphoserine390 def: "Protein ATX2L_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065776 name: ATX2L_HUMAN-Phosphoserine391 def: "Protein ATX2L_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065777 name: ATX2L_HUMAN-Phosphoserine409 def: "Protein ATX2L_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065778 name: ATX2L_HUMAN-Phosphoserine449 def: "Protein ATX2L_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065779 name: ATX2L_HUMAN-Phosphoserine493 def: "Protein ATX2L_HUMAN with the residue 493 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065780 name: ATX2L_HUMAN-Phosphoserine496 def: "Protein ATX2L_HUMAN with the residue 496 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065781 name: ATX2L_HUMAN-Phosphoserine557 def: "Protein ATX2L_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065782 name: ATX2L_HUMAN-Phosphoserine558 def: "Protein ATX2L_HUMAN with the residue 558 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065783 name: ATX2L_HUMAN-Phosphoserine559 def: "Protein ATX2L_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065784 name: ATX2L_HUMAN-Phosphoserine563 def: "Protein ATX2L_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065785 name: ATX2L_HUMAN-Phosphoserine589 def: "Protein ATX2L_HUMAN with the residue 589 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065786 name: ATX2L_HUMAN-Phosphoserine594 def: "Protein ATX2L_HUMAN with the residue 594 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065787 name: ATX2L_HUMAN-Phosphoserine597 def: "Protein ATX2L_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065788 name: ATX2L_HUMAN-Phosphoserine598 def: "Protein ATX2L_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065789 name: ATX2L_HUMAN-Phosphoserine630 def: "Protein ATX2L_HUMAN with the residue 630 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065790 name: ATX2L_HUMAN-Phosphoserine634 def: "Protein ATX2L_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065791 name: ATX2L_HUMAN-Phosphoserine684 def: "Protein ATX2L_HUMAN with the residue 684 substituted with Phosphoserine" [UniProtKB:Q8WWM7] xref: UniProtKB:Q8WWM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:B0065792 name: BAHD1_HUMAN-Phosphoserine101 def: "Protein BAHD1_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:Q8TBE0] xref: UniProtKB:Q8TBE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062793 ! BAHD1_HUMAN [Term] id: CCO:B0065793 name: BAHD1_HUMAN-Phosphoserine121 def: "Protein BAHD1_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q8TBE0] xref: UniProtKB:Q8TBE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062793 ! BAHD1_HUMAN [Term] id: CCO:B0065794 name: BCORL_HUMAN-Phosphoserine48 def: "Protein BCORL_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q5H9F3] xref: UniProtKB:Q5H9F3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056438 ! BCORL_HUMAN [Term] id: CCO:B0065795 name: BCORL_HUMAN-Phosphoserine613 def: "Protein BCORL_HUMAN with the residue 613 substituted with Phosphoserine" [UniProtKB:Q5H9F3] xref: UniProtKB:Q5H9F3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056438 ! BCORL_HUMAN [Term] id: CCO:B0065796 name: BCORL_HUMAN-Phosphoserine1033 def: "Protein BCORL_HUMAN with the residue 1033 substituted with Phosphoserine" [UniProtKB:Q5H9F3] xref: UniProtKB:Q5H9F3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056438 ! BCORL_HUMAN [Term] id: CCO:B0065797 name: BCORL_HUMAN-Phosphoserine1162 def: "Protein BCORL_HUMAN with the residue 1162 substituted with Phosphoserine" [UniProtKB:Q5H9F3] xref: UniProtKB:Q5H9F3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056438 ! BCORL_HUMAN [Term] id: CCO:B0065798 name: BL1S1_HUMAN-Phosphothreonine107 def: "Protein BL1S1_HUMAN with the residue 107 substituted with Phosphothreonine" [UniProtKB:P78537] xref: UniProtKB:P78537 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0006194 ! BL1S1_HUMAN [Term] id: CCO:B0065799 name: BR44L_HUMAN-N-acetylalanine2 def: "Protein BR44L_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y5U8] comment: By similarity xref: UniProtKB:Q9Y5U8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0063470 ! BR44L_HUMAN [Term] id: CCO:B0065800 name: C1QBP_HUMAN-Phosphotyrosine188 def: "Protein C1QBP_HUMAN with the residue 188 substituted with Phosphotyrosine" [UniProtKB:Q07021] xref: UniProtKB:Q07021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:B0065801 name: C1QBP_HUMAN-Phosphoserine201 def: "Protein C1QBP_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:Q07021] xref: UniProtKB:Q07021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000223 ! complement component C1q binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:B0065802 name: C43BP_HUMAN-Phosphoserine132 def: "Protein C43BP_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q9Y5P4] comment: by PKD; xref: UniProtKB:Q9Y5P4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:B0065803 name: C43BP_HUMAN-Phosphoserine315 def: "Protein C43BP_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q9Y5P4] xref: UniProtKB:Q9Y5P4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:B0065804 name: C43BP_HUMAN-Phosphoserine377 def: "Protein C43BP_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q9Y5P4] xref: UniProtKB:Q9Y5P4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:B0065805 name: C43BP_HUMAN-Phosphoserine380 def: "Protein C43BP_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q9Y5P4] comment: By similarity xref: UniProtKB:Q9Y5P4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:B0065806 name: C43BP_HUMAN-Phosphoserine611 def: "Protein C43BP_HUMAN with the residue 611 substituted with Phosphoserine" [UniProtKB:Q9Y5P4] comment: By similarity xref: UniProtKB:Q9Y5P4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:B0065807 name: CA149_HUMAN-Phosphoserine118 def: "Protein CA149_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q9HAF1] xref: UniProtKB:Q9HAF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049761 ! CA149_HUMAN [Term] id: CCO:B0065808 name: CA149_HUMAN-Phosphothreonine120 def: "Protein CA149_HUMAN with the residue 120 substituted with Phosphothreonine" [UniProtKB:Q9HAF1] xref: UniProtKB:Q9HAF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049761 ! CA149_HUMAN [Term] id: CCO:B0065809 name: CA149_HUMAN-Phosphoserine122 def: "Protein CA149_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q9HAF1] xref: UniProtKB:Q9HAF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049761 ! CA149_HUMAN [Term] id: CCO:B0065810 name: CAD10_HUMAN-Phosphoserine784 def: "Protein CAD10_HUMAN with the residue 784 substituted with Phosphoserine" [UniProtKB:Q9Y6N8] xref: UniProtKB:Q9Y6N8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0006177 ! CAD10_HUMAN [Term] id: CCO:B0065811 name: CALU_HUMAN-Phosphoserine44 def: "Protein CALU_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:O43852] xref: UniProtKB:O43852 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063209 ! CALU_HUMAN [Term] id: CCO:B0065812 name: CALU_HUMAN-Phosphothreonine65 def: "Protein CALU_HUMAN with the residue 65 substituted with Phosphothreonine" [UniProtKB:O43852] xref: UniProtKB:O43852 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063209 ! CALU_HUMAN [Term] id: CCO:B0065813 name: CALX_HUMAN-Phosphoserine554 def: "Protein CALX_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:P27824] xref: UniProtKB:P27824 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063067 ! CALX_HUMAN [Term] id: CCO:B0065814 name: CALX_HUMAN-Phosphothreonine562 def: "Protein CALX_HUMAN with the residue 562 substituted with Phosphothreonine" [UniProtKB:P27824] xref: UniProtKB:P27824 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063067 ! CALX_HUMAN [Term] id: CCO:B0065815 name: CALX_HUMAN-Phosphoserine564 def: "Protein CALX_HUMAN with the residue 564 substituted with Phosphoserine" [UniProtKB:P27824] xref: UniProtKB:P27824 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063067 ! CALX_HUMAN [Term] id: CCO:B0065816 name: CALX_HUMAN-Phosphoserine583 def: "Protein CALX_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:P27824] xref: UniProtKB:P27824 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063067 ! CALX_HUMAN [Term] id: CCO:B0065817 name: CALY_HUMAN-Phosphotyrosine151 def: "Protein CALY_HUMAN with the residue 151 substituted with Phosphotyrosine" [UniProtKB:Q9NYX4] xref: UniProtKB:Q9NYX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0004940 ! clathrin light chain binding relationship: has_function CCO:F0008009 ! dopamine receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0058986 ! CALY_HUMAN [Term] id: CCO:B0065818 name: CAPR1_HUMAN-Phosphoserine611 def: "Protein CAPR1_HUMAN with the residue 611 substituted with Phosphoserine" [UniProtKB:Q14444] xref: UniProtKB:Q14444 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0063346 ! CAPR1_HUMAN [Term] id: CCO:B0065819 name: CAPR1_HUMAN-Phosphoserine615 def: "Protein CAPR1_HUMAN with the residue 615 substituted with Phosphoserine" [UniProtKB:Q14444] xref: UniProtKB:Q14444 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063346 ! CAPR1_HUMAN [Term] id: CCO:B0065820 name: CASC3_HUMAN-Phosphoserine363 def: "Protein CASC3_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:O15234] xref: UniProtKB:O15234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0063246 ! CASC3_HUMAN [Term] id: CCO:B0065821 name: CASC3_HUMAN-Phosphoserine373 def: "Protein CASC3_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:O15234] xref: UniProtKB:O15234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063246 ! CASC3_HUMAN [Term] id: CCO:B0065822 name: CASS4_HUMAN-Phosphoserine200 def: "Protein CASS4_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q9NQ75] xref: UniProtKB:Q9NQ75 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022762 ! CASS4_HUMAN [Term] id: CCO:B0065823 name: CASS4_HUMAN-Phosphoserine249 def: "Protein CASS4_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q9NQ75] xref: UniProtKB:Q9NQ75 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022762 ! CASS4_HUMAN [Term] id: CCO:B0065824 name: CASS4_HUMAN-Phosphoserine305 def: "Protein CASS4_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q9NQ75] xref: UniProtKB:Q9NQ75 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022762 ! CASS4_HUMAN [Term] id: CCO:B0065825 name: CASS4_HUMAN-Phosphotyrosine329 def: "Protein CASS4_HUMAN with the residue 329 substituted with Phosphotyrosine" [UniProtKB:Q9NQ75] xref: UniProtKB:Q9NQ75 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022762 ! CASS4_HUMAN [Term] id: CCO:B0065826 name: CASS4_HUMAN-Phosphotyrosine350 def: "Protein CASS4_HUMAN with the residue 350 substituted with Phosphotyrosine" [UniProtKB:Q9NQ75] xref: UniProtKB:Q9NQ75 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022762 ! CASS4_HUMAN [Term] id: CCO:B0065827 name: CASS4_HUMAN-Phosphoserine390 def: "Protein CASS4_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:Q9NQ75] xref: UniProtKB:Q9NQ75 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022762 ! CASS4_HUMAN [Term] id: CCO:B0065828 name: CB044_HUMAN-Phosphoserine529 def: "Protein CB044_HUMAN with the residue 529 substituted with Phosphoserine" [UniProtKB:Q9H6R7] xref: UniProtKB:Q9H6R7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063461 ! CB044_HUMAN [Term] id: CCO:B0065829 name: CB044_HUMAN-Phosphothreonine530 def: "Protein CB044_HUMAN with the residue 530 substituted with Phosphothreonine" [UniProtKB:Q9H6R7] xref: UniProtKB:Q9H6R7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063461 ! CB044_HUMAN [Term] id: CCO:B0065830 name: CB044_HUMAN-Phosphoserine690 def: "Protein CB044_HUMAN with the residue 690 substituted with Phosphoserine" [UniProtKB:Q9H6R7] xref: UniProtKB:Q9H6R7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063461 ! CB044_HUMAN [Term] id: CCO:B0065831 name: CBR1_HUMAN-N-acetylserine2 def: "Protein CBR1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P16152] xref: UniProtKB:P16152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063371 ! CBR1_HUMAN [Term] id: CCO:B0065832 name: CBR1_HUMAN-Phosphotyrosine194 def: "Protein CBR1_HUMAN with the residue 194 substituted with Phosphotyrosine" [UniProtKB:P16152] xref: UniProtKB:P16152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063371 ! CBR1_HUMAN [Term] id: CCO:B0065833 name: CBR1_HUMAN-N6-1-carboxyethyl lysine239 def: "Protein CBR1_HUMAN with the residue 239 substituted with N6-1-carboxyethyl lysine" [UniProtKB:P16152] xref: UniProtKB:P16152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000565 ! carbonyl reductase (NADPH) activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0006334 ! 15-hydroxyprostaglandin dehydrogenase (NADP+) activity relationship: has_function CCO:F0007574 ! prostaglandin-E2 9-reductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063371 ! CBR1_HUMAN [Term] id: CCO:B0065834 name: CC120_HUMAN-Phosphoserine331 def: "Protein CC120_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q96HB5] xref: UniProtKB:Q96HB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062828 ! CC120_HUMAN [Term] id: CCO:B0065835 name: CC120_HUMAN-Phosphoserine358 def: "Protein CC120_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:Q96HB5] xref: UniProtKB:Q96HB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062828 ! CC120_HUMAN [Term] id: CCO:B0065836 name: CC137_HUMAN-Phosphoserine19 def: "Protein CC137_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q6PK04] xref: UniProtKB:Q6PK04 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063473 ! CC137_HUMAN [Term] id: CCO:B0065837 name: CC137_HUMAN-Phosphoserine233 def: "Protein CC137_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:Q6PK04] xref: UniProtKB:Q6PK04 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063473 ! CC137_HUMAN [Term] id: CCO:B0065838 name: CC28A_HUMAN-Phosphotyrosine26 def: "Protein CC28A_HUMAN with the residue 26 substituted with Phosphotyrosine" [UniProtKB:Q8IWP9] xref: UniProtKB:Q8IWP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063052 ! CC28A_HUMAN [Term] id: CCO:B0065839 name: CCD50_HUMAN-Phosphotyrosine140 def: "Protein CCD50_HUMAN with the residue 140 substituted with Phosphotyrosine" [UniProtKB:Q8IVM0] xref: UniProtKB:Q8IVM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063501 ! CCD50_HUMAN [Term] id: CCO:B0065840 name: CCD50_HUMAN-Phosphotyrosine144 def: "Protein CCD50_HUMAN with the residue 144 substituted with Phosphotyrosine" [UniProtKB:Q8IVM0] xref: UniProtKB:Q8IVM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063501 ! CCD50_HUMAN [Term] id: CCO:B0065841 name: CCD50_HUMAN-Phosphotyrosine145 def: "Protein CCD50_HUMAN with the residue 145 substituted with Phosphotyrosine" [UniProtKB:Q8IVM0] xref: UniProtKB:Q8IVM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063501 ! CCD50_HUMAN [Term] id: CCO:B0065842 name: CCD50_HUMAN-Phosphotyrosine279 def: "Protein CCD50_HUMAN with the residue 279 substituted with Phosphotyrosine" [UniProtKB:Q8IVM0] xref: UniProtKB:Q8IVM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063501 ! CCD50_HUMAN [Term] id: CCO:B0065843 name: CD22_HUMAN-Phosphotyrosine762 def: "Protein CD22_HUMAN with the residue 762 substituted with Phosphotyrosine" [UniProtKB:P20273] comment: By similarity xref: UniProtKB:P20273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:B0065844 name: CD22_HUMAN-Phosphotyrosine807 def: "Protein CD22_HUMAN with the residue 807 substituted with Phosphotyrosine" [UniProtKB:P20273] comment: By similarity xref: UniProtKB:P20273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:B0065845 name: CD22_HUMAN-Phosphotyrosine822 def: "Protein CD22_HUMAN with the residue 822 substituted with Phosphotyrosine" [UniProtKB:P20273] comment: By similarity xref: UniProtKB:P20273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:B0065846 name: CD22_HUMAN-Phosphotyrosine842 def: "Protein CD22_HUMAN with the residue 842 substituted with Phosphotyrosine" [UniProtKB:P20273] comment: By similarity xref: UniProtKB:P20273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:B0065847 name: CE350_HUMAN-Phosphothreonine878 def: "Protein CE350_HUMAN with the residue 878 substituted with Phosphothreonine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065848 name: CE350_HUMAN-Phosphothreonine1253 def: "Protein CE350_HUMAN with the residue 1253 substituted with Phosphothreonine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065849 name: CE350_HUMAN-Phosphoserine1256 def: "Protein CE350_HUMAN with the residue 1256 substituted with Phosphoserine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065850 name: CE350_HUMAN-Phosphoserine1259 def: "Protein CE350_HUMAN with the residue 1259 substituted with Phosphoserine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000388 ! spindle relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065851 name: CE350_HUMAN-Phosphoserine1818 def: "Protein CE350_HUMAN with the residue 1818 substituted with Phosphoserine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065852 name: CE350_HUMAN-Phosphothreonine2204 def: "Protein CE350_HUMAN with the residue 2204 substituted with Phosphothreonine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065853 name: CE350_HUMAN-Phosphoserine2206 def: "Protein CE350_HUMAN with the residue 2206 substituted with Phosphoserine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065854 name: CE350_HUMAN-Phosphoserine2460 def: "Protein CE350_HUMAN with the residue 2460 substituted with Phosphoserine" [UniProtKB:Q5VT06] xref: UniProtKB:Q5VT06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:B0065855 name: CEP72_HUMAN-Phosphoserine237 def: "Protein CEP72_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q9P209] xref: UniProtKB:Q9P209 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0062905 ! CEP72_HUMAN [Term] id: CCO:B0065856 name: CHM2B_HUMAN-Phosphoserine199 def: "Protein CHM2B_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q9UQN3] xref: UniProtKB:Q9UQN3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0062894 ! CHM2B_HUMAN [Term] id: CCO:B0065857 name: CI025_HUMAN-Phosphoserine102 def: "Protein CI025_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q8IW50] xref: UniProtKB:Q8IW50 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063447 ! CI025_HUMAN [Term] id: CCO:B0065858 name: CI025_HUMAN-Phosphothreonine113 def: "Protein CI025_HUMAN with the residue 113 substituted with Phosphothreonine" [UniProtKB:Q8IW50] xref: UniProtKB:Q8IW50 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063447 ! CI025_HUMAN [Term] id: CCO:B0065859 name: CI025_HUMAN-Phosphoserine115 def: "Protein CI025_HUMAN with the residue 115 substituted with Phosphoserine" [UniProtKB:Q8IW50] xref: UniProtKB:Q8IW50 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063447 ! CI025_HUMAN [Term] id: CCO:B0065860 name: CIC_HUMAN-Phosphoserine279 def: "Protein CIC_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q96RK0] xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065861 name: CIC_HUMAN-Phosphoserine904 def: "Protein CIC_HUMAN with the residue 904 substituted with Phosphoserine" [UniProtKB:Q96RK0] comment: By similarity xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065862 name: CIC_HUMAN-Phosphothreonine1291 def: "Protein CIC_HUMAN with the residue 1291 substituted with Phosphothreonine" [UniProtKB:Q96RK0] comment: By similarity xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065863 name: CIC_HUMAN-Phosphoserine1294 def: "Protein CIC_HUMAN with the residue 1294 substituted with Phosphoserine" [UniProtKB:Q96RK0] comment: By similarity xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065864 name: CIC_HUMAN-Phosphoserine1373 def: "Protein CIC_HUMAN with the residue 1373 substituted with Phosphoserine" [UniProtKB:Q96RK0] xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065865 name: CIC_HUMAN-Phosphoserine1378 def: "Protein CIC_HUMAN with the residue 1378 substituted with Phosphoserine" [UniProtKB:Q96RK0] xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065866 name: CIC_HUMAN-Phosphoserine1382 def: "Protein CIC_HUMAN with the residue 1382 substituted with Phosphoserine" [UniProtKB:Q96RK0] xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065867 name: CIC_HUMAN-Phosphoserine1397 def: "Protein CIC_HUMAN with the residue 1397 substituted with Phosphoserine" [UniProtKB:Q96RK0] xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065868 name: CIC_HUMAN-Phosphoserine1402 def: "Protein CIC_HUMAN with the residue 1402 substituted with Phosphoserine" [UniProtKB:Q96RK0] comment: By similarity xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065869 name: CIC_HUMAN-Phosphoserine1409 def: "Protein CIC_HUMAN with the residue 1409 substituted with Phosphoserine" [UniProtKB:Q96RK0] xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065870 name: CIC_HUMAN-Phosphoserine1462 def: "Protein CIC_HUMAN with the residue 1462 substituted with Phosphoserine" [UniProtKB:Q96RK0] xref: UniProtKB:Q96RK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:B0065871 name: CJ012_HUMAN-Phosphoserine273 def: "Protein CJ012_HUMAN with the residue 273 substituted with Phosphoserine" [UniProtKB:Q8N655] xref: UniProtKB:Q8N655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062958 ! CJ012_HUMAN [Term] id: CCO:B0065872 name: CJ012_HUMAN-Phosphothreonine428 def: "Protein CJ012_HUMAN with the residue 428 substituted with Phosphothreonine" [UniProtKB:Q8N655] xref: UniProtKB:Q8N655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062958 ! CJ012_HUMAN [Term] id: CCO:B0065873 name: CJ012_HUMAN-Phosphothreonine993 def: "Protein CJ012_HUMAN with the residue 993 substituted with Phosphothreonine" [UniProtKB:Q8N655] xref: UniProtKB:Q8N655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062958 ! CJ012_HUMAN [Term] id: CCO:B0065874 name: CJ012_HUMAN-Phosphoserine996 def: "Protein CJ012_HUMAN with the residue 996 substituted with Phosphoserine" [UniProtKB:Q8N655] xref: UniProtKB:Q8N655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062958 ! CJ012_HUMAN [Term] id: CCO:B0065875 name: CK061_HUMAN-Phosphoserine48 def: "Protein CK061_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q6P1R3] xref: UniProtKB:Q6P1R3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063536 ! CK061_HUMAN [Term] id: CCO:B0065876 name: CK061_HUMAN-Phosphoserine436 def: "Protein CK061_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q6P1R3] comment: By similarity xref: UniProtKB:Q6P1R3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063536 ! CK061_HUMAN [Term] id: CCO:B0065877 name: CL011_HUMAN-Phosphoserine626 def: "Protein CL011_HUMAN with the residue 626 substituted with Phosphoserine" [UniProtKB:Q9NVM9] xref: UniProtKB:Q9NVM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062783 ! CL011_HUMAN [Term] id: CCO:B0065878 name: CLCB_HUMAN-Phosphoserine11 def: "Protein CLCB_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P09497] comment: By similarity xref: UniProtKB:P09497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063531 ! CLCB_HUMAN [Term] id: CCO:B0065879 name: CLCB_HUMAN-Phosphoserine13 def: "Protein CLCB_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P09497] comment: By similarity xref: UniProtKB:P09497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063531 ! CLCB_HUMAN [Term] id: CCO:B0065880 name: CLD12_HUMAN-Phosphoserine228 def: "Protein CLD12_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:P56749] comment: By similarity xref: UniProtKB:P56749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0063489 ! CLD12_HUMAN [Term] id: CCO:B0065881 name: CLH1_HUMAN-N-acetylalanine2 def: "Protein CLH1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q00610] xref: UniProtKB:Q00610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:B0065882 name: CLH1_HUMAN-Phosphothreonine394 def: "Protein CLH1_HUMAN with the residue 394 substituted with Phosphothreonine" [UniProtKB:Q00610] xref: UniProtKB:Q00610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:B0065883 name: CLH1_HUMAN-Phosphotyrosine634 def: "Protein CLH1_HUMAN with the residue 634 substituted with Phosphotyrosine" [UniProtKB:Q00610] xref: UniProtKB:Q00610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:B0065884 name: CLH1_HUMAN-Phosphotyrosine899 def: "Protein CLH1_HUMAN with the residue 899 substituted with Phosphotyrosine" [UniProtKB:Q00610] xref: UniProtKB:Q00610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:B0065885 name: CLH1_HUMAN-Phosphoserine1494 def: "Protein CLH1_HUMAN with the residue 1494 substituted with Phosphoserine" [UniProtKB:Q00610] xref: UniProtKB:Q00610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:B0065886 name: CN37_HUMAN-Phosphotyrosine110 def: "Protein CN37_HUMAN with the residue 110 substituted with Phosphotyrosine" [UniProtKB:P09543] comment: By similarity xref: UniProtKB:P09543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063255 ! CN37_HUMAN [Term] id: CCO:B0065887 name: CN37_HUMAN-Phosphotyrosine373 def: "Protein CN37_HUMAN with the residue 373 substituted with Phosphotyrosine" [UniProtKB:P09543] comment: By similarity xref: UniProtKB:P09543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063255 ! CN37_HUMAN [Term] id: CCO:B0065888 name: COG4_HUMAN-Phosphotyrosine714 def: "Protein COG4_HUMAN with the residue 714 substituted with Phosphotyrosine" [UniProtKB:Q9H9E3] xref: UniProtKB:Q9H9E3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000842 ! Golgi transport complex relationship: transformation_of CCO:B0063023 ! COG4_HUMAN [Term] id: CCO:B0065889 name: COG5_HUMAN-Phosphoserine197 def: "Protein COG5_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q9UP83] xref: UniProtKB:Q9UP83 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063024 ! COG5_HUMAN [Term] id: CCO:B0065890 name: COMT_HUMAN-Phosphoserine267 def: "Protein COMT_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:P21964] comment: By similarity xref: UniProtKB:P21964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063160 ! COMT_HUMAN [Term] id: CCO:B0065891 name: CPSF5_HUMAN-Phosphotyrosine40 def: "Protein CPSF5_HUMAN with the residue 40 substituted with Phosphotyrosine" [UniProtKB:O43809] xref: UniProtKB:O43809 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0001637 ! paraspeckles relationship: transformation_of CCO:B0062837 ! CPSF5_HUMAN [Term] id: CCO:B0065892 name: CPSF6_HUMAN-Phosphoserine165 def: "Protein CPSF6_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q16630] xref: UniProtKB:Q16630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063126 ! CPSF6_HUMAN [Term] id: CCO:B0065893 name: CPSF6_HUMAN-Phosphothreonine404 def: "Protein CPSF6_HUMAN with the residue 404 substituted with Phosphothreonine" [UniProtKB:Q16630] xref: UniProtKB:Q16630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000415 ! mRNA cleavage factor complex relationship: located_in CCO:C0001637 ! paraspeckles relationship: transformation_of CCO:B0063126 ! CPSF6_HUMAN [Term] id: CCO:B0065894 name: CPSF7_HUMAN-Phosphotyrosine72 def: "Protein CPSF7_HUMAN with the residue 72 substituted with Phosphotyrosine" [UniProtKB:Q8N684] xref: UniProtKB:Q8N684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:B0065895 name: CPSF7_HUMAN-Phosphothreonine73 def: "Protein CPSF7_HUMAN with the residue 73 substituted with Phosphothreonine" [UniProtKB:Q8N684] xref: UniProtKB:Q8N684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:B0065896 name: CPSF7_HUMAN-Phosphoserine197 def: "Protein CPSF7_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q8N684] xref: UniProtKB:Q8N684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:B0065897 name: CPSF7_HUMAN-Phosphothreonine203 def: "Protein CPSF7_HUMAN with the residue 203 substituted with Phosphothreonine" [UniProtKB:Q8N684] xref: UniProtKB:Q8N684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:B0065898 name: CPSF7_HUMAN-Phosphoserine413 def: "Protein CPSF7_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q8N684] xref: UniProtKB:Q8N684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:B0065899 name: CPSF7_HUMAN-Phosphoserine423 def: "Protein CPSF7_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:Q8N684] xref: UniProtKB:Q8N684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:B0065900 name: CPSF7_HUMAN-Phosphoserine429 def: "Protein CPSF7_HUMAN with the residue 429 substituted with Phosphoserine" [UniProtKB:Q8N684] xref: UniProtKB:Q8N684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:B0065901 name: CPSM_HUMAN-N6-acetyllysine55 def: "Protein CPSM_HUMAN with the residue 55 substituted with N6-acetyllysine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065902 name: CPSM_HUMAN-N6-acetyllysine119 def: "Protein CPSM_HUMAN with the residue 119 substituted with N6-acetyllysine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065903 name: CPSM_HUMAN-N6-acetyllysine287 def: "Protein CPSM_HUMAN with the residue 287 substituted with N6-acetyllysine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065904 name: CPSM_HUMAN-N6-acetyllysine527 def: "Protein CPSM_HUMAN with the residue 527 substituted with N6-acetyllysine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065905 name: CPSM_HUMAN-N6-acetyllysine841 def: "Protein CPSM_HUMAN with the residue 841 substituted with N6-acetyllysine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000561 ! carbamoyl-phosphate synthase activity relationship: has_function CCO:F0000562 ! carbamoyl-phosphate synthase (ammonia) activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065906 name: CPSM_HUMAN-N6-acetyllysine892 def: "Protein CPSM_HUMAN with the residue 892 substituted with N6-acetyllysine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065907 name: CPSM_HUMAN-Phosphoserine898 def: "Protein CPSM_HUMAN with the residue 898 substituted with Phosphoserine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065908 name: CPSM_HUMAN-N6-acetyllysine1291 def: "Protein CPSM_HUMAN with the residue 1291 substituted with N6-acetyllysine" [UniProtKB:P31327] comment: By similarity xref: UniProtKB:P31327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:B0065909 name: CS029_HUMAN-Phosphoserine421 def: "Protein CS029_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q8WUQ7] xref: UniProtKB:Q8WUQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063276 ! CS029_HUMAN [Term] id: CCO:B0065910 name: CSTF2_HUMAN-Phosphoserine154 def: "Protein CSTF2_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:P33240] xref: UniProtKB:P33240 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063344 ! CSTF2_HUMAN [Term] id: CCO:B0065911 name: CSTF2_HUMAN-Phosphoserine518 def: "Protein CSTF2_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:P33240] xref: UniProtKB:P33240 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063344 ! CSTF2_HUMAN [Term] id: CCO:B0065912 name: CSTF2_HUMAN-Phosphoserine524 def: "Protein CSTF2_HUMAN with the residue 524 substituted with Phosphoserine" [UniProtKB:P33240] xref: UniProtKB:P33240 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063344 ! CSTF2_HUMAN [Term] id: CCO:B0065913 name: CUL7_HUMAN-Phosphoserine329 def: "Protein CUL7_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q14999] xref: UniProtKB:Q14999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004689 ! ubiquitin protein ligase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000282 ! anaphase-promoting complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: transformation_of CCO:B0001795 ! CUL7_HUMAN [Term] id: CCO:B0065914 name: CUL7_HUMAN-Phosphoserine339 def: "Protein CUL7_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:Q14999] xref: UniProtKB:Q14999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001795 ! CUL7_HUMAN [Term] id: CCO:B0065915 name: CX026_HUMAN-Phosphoserine126 def: "Protein CX026_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q9BVG4] xref: UniProtKB:Q9BVG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063537 ! CX026_HUMAN [Term] id: CCO:B0065916 name: CX026_HUMAN-Phosphoserine197 def: "Protein CX026_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q9BVG4] xref: UniProtKB:Q9BVG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063537 ! CX026_HUMAN [Term] id: CCO:B0065917 name: CXAR_HUMAN-Phosphoserine293 def: "Protein CXAR_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:P78310] comment: By similarity xref: UniProtKB:P78310 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062878 ! CXAR_HUMAN [Term] id: CCO:B0065918 name: CXAR_HUMAN-Phosphoserine300 def: "Protein CXAR_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:P78310] comment: By similarity xref: UniProtKB:P78310 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000780 ! basolateral plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0062878 ! CXAR_HUMAN [Term] id: CCO:B0065919 name: CXAR_HUMAN-Phosphoserine306 def: "Protein CXAR_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:P78310] xref: UniProtKB:P78310 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062878 ! CXAR_HUMAN [Term] id: CCO:B0065920 name: CXAR_HUMAN-Phosphoserine323 def: "Protein CXAR_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:P78310] comment: By similarity xref: UniProtKB:P78310 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062878 ! CXAR_HUMAN [Term] id: CCO:B0065921 name: CXAR_HUMAN-Phosphoserine332 def: "Protein CXAR_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:P78310] xref: UniProtKB:P78310 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062878 ! CXAR_HUMAN [Term] id: CCO:B0065922 name: CYTB_HUMAN-N-acetylmethionine1 def: "Protein CYTB_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P04080] comment: Probable xref: UniProtKB:P04080 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063207 ! CYTB_HUMAN [Term] id: CCO:B0065923 name: DC1L2_HUMAN-Phosphoserine194 def: "Protein DC1L2_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:O43237] xref: UniProtKB:O43237 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063409 ! DC1L2_HUMAN [Term] id: CCO:B0065924 name: DC1L2_HUMAN-Phosphoserine446 def: "Protein DC1L2_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:O43237] xref: UniProtKB:O43237 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063409 ! DC1L2_HUMAN [Term] id: CCO:B0065925 name: DCTD_HUMAN-Phosphotyrosine79 def: "Protein DCTD_HUMAN with the residue 79 substituted with Phosphotyrosine" [UniProtKB:P32321] xref: UniProtKB:P32321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000603 ! dCMP deaminase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0062960 ! DCTD_HUMAN [Term] id: CCO:B0065926 name: DDX17_HUMAN-Phosphotyrosine200 def: "Protein DDX17_HUMAN with the residue 200 substituted with Phosphotyrosine" [UniProtKB:Q92841] xref: UniProtKB:Q92841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062841 ! DDX17_HUMAN [Term] id: CCO:B0065927 name: DDX17_HUMAN-Phosphothreonine444 def: "Protein DDX17_HUMAN with the residue 444 substituted with Phosphothreonine" [UniProtKB:Q92841] xref: UniProtKB:Q92841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062841 ! DDX17_HUMAN [Term] id: CCO:B0065928 name: DDX17_HUMAN-Phosphoserine593 def: "Protein DDX17_HUMAN with the residue 593 substituted with Phosphoserine" [UniProtKB:Q92841] xref: UniProtKB:Q92841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062841 ! DDX17_HUMAN [Term] id: CCO:B0065929 name: DDX17_HUMAN-Phosphoserine597 def: "Protein DDX17_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:Q92841] xref: UniProtKB:Q92841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062841 ! DDX17_HUMAN [Term] id: CCO:B0065930 name: DDX21_HUMAN-Phosphoserine13 def: "Protein DDX21_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0065931 name: DDX21_HUMAN-Phosphoserine164 def: "Protein DDX21_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0065932 name: DDX21_HUMAN-Phosphoserine168 def: "Protein DDX21_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0065933 name: DDX21_HUMAN-Phosphoserine173 def: "Protein DDX21_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0065934 name: DDX21_HUMAN-Phosphothreonine315 def: "Protein DDX21_HUMAN with the residue 315 substituted with Phosphothreonine" [UniProtKB:Q9NR30] xref: UniProtKB:Q9NR30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:B0065935 name: DDX23_HUMAN-Phosphoserine14 def: "Protein DDX23_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q9BUQ8] xref: UniProtKB:Q9BUQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063187 ! DDX23_HUMAN [Term] id: CCO:B0065936 name: DDX23_HUMAN-Phosphothreonine25 def: "Protein DDX23_HUMAN with the residue 25 substituted with Phosphothreonine" [UniProtKB:Q9BUQ8] xref: UniProtKB:Q9BUQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063187 ! DDX23_HUMAN [Term] id: CCO:B0065937 name: DDX23_HUMAN-Phosphoserine107 def: "Protein DDX23_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:Q9BUQ8] xref: UniProtKB:Q9BUQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000284 ! snRNP U5 relationship: transformation_of CCO:B0063187 ! DDX23_HUMAN [Term] id: CCO:B0065938 name: DDX23_HUMAN-Phosphoserine109 def: "Protein DDX23_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q9BUQ8] xref: UniProtKB:Q9BUQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063187 ! DDX23_HUMAN [Term] id: CCO:B0065939 name: DDX50_HUMAN-Phosphoserine45 def: "Protein DDX50_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q9BQ39] xref: UniProtKB:Q9BQ39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063176 ! DDX50_HUMAN [Term] id: CCO:B0065940 name: DDX50_HUMAN-Phosphoserine82 def: "Protein DDX50_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q9BQ39] xref: UniProtKB:Q9BQ39 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063176 ! DDX50_HUMAN [Term] id: CCO:B0065941 name: DDX52_HUMAN-Phosphoserine39 def: "Protein DDX52_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q9Y2R4] xref: UniProtKB:Q9Y2R4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063171 ! DDX52_HUMAN [Term] id: CCO:B0065942 name: DDX52_HUMAN-Phosphoserine99 def: "Protein DDX52_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q9Y2R4] xref: UniProtKB:Q9Y2R4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063171 ! DDX52_HUMAN [Term] id: CCO:B0065943 name: DESP_HUMAN-Phosphotyrosine28 def: "Protein DESP_HUMAN with the residue 28 substituted with Phosphotyrosine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0065944 name: DESP_HUMAN-Phosphotyrosine56 def: "Protein DESP_HUMAN with the residue 56 substituted with Phosphotyrosine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0065945 name: DESP_HUMAN-Phosphotyrosine2275 def: "Protein DESP_HUMAN with the residue 2275 substituted with Phosphotyrosine" [UniProtKB:P15924] xref: UniProtKB:P15924 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:B0065946 name: DHB4_HUMAN-Phosphoserine3 def: "Protein DHB4_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:P51659] comment: By similarity xref: UniProtKB:P51659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063125 ! DHB4_HUMAN [Term] id: CCO:B0065947 name: DHB4_HUMAN-Phosphoserine309 def: "Protein DHB4_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:P51659] comment: By similarity xref: UniProtKB:P51659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000376 ! 3-hydroxyacyl-CoA dehydrogenase activity relationship: has_function CCO:F0000724 ! estradiol 17-beta-dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001636 ! sterol carrier activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002716 ! sterol transporter activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003402 ! hydro-lyase activity relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0005463 ! 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000363 ! peroxisomal matrix relationship: transformation_of CCO:B0063125 ! DHB4_HUMAN [Term] id: CCO:B0065948 name: DHB4_HUMAN-N6-acetyllysine663 def: "Protein DHB4_HUMAN with the residue 663 substituted with N6-acetyllysine" [UniProtKB:P51659] comment: By similarity xref: UniProtKB:P51659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063125 ! DHB4_HUMAN [Term] id: CCO:B0065949 name: DHX29_HUMAN-Phosphoserine192 def: "Protein DHX29_HUMAN with the residue 192 substituted with Phosphoserine" [UniProtKB:Q7Z478] xref: UniProtKB:Q7Z478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063506 ! DHX29_HUMAN [Term] id: CCO:B0065950 name: DHX29_HUMAN-Phosphoserine200 def: "Protein DHX29_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q7Z478] xref: UniProtKB:Q7Z478 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063506 ! DHX29_HUMAN [Term] id: CCO:B0065951 name: DICER_HUMAN-Phosphotyrosine654 def: "Protein DICER_HUMAN with the residue 654 substituted with Phosphotyrosine" [UniProtKB:Q9UPY3] xref: UniProtKB:Q9UPY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:B0065952 name: DICER_HUMAN-Phosphoserine1006 def: "Protein DICER_HUMAN with the residue 1006 substituted with Phosphoserine" [UniProtKB:Q9UPY3] xref: UniProtKB:Q9UPY3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:B0065953 name: DLDH_HUMAN-N6-acetyllysine127 def: "Protein DLDH_HUMAN with the residue 127 substituted with N6-acetyllysine" [UniProtKB:P09622] comment: By similarity xref: UniProtKB:P09622 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000619 ! dihydrolipoyl dehydrogenase activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0007986 ! FAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0063359 ! DLDH_HUMAN [Term] id: CCO:B0065954 name: DNJB4_HUMAN-Phosphoserine122 def: "Protein DNJB4_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q9UDY4] xref: UniProtKB:Q9UDY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016224 ! DNJB4_HUMAN [Term] id: CCO:B0065955 name: DNJC7_HUMAN-Phosphotyrosine50 def: "Protein DNJC7_HUMAN with the residue 50 substituted with Phosphotyrosine" [UniProtKB:Q99615] xref: UniProtKB:Q99615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063120 ! DNJC7_HUMAN [Term] id: CCO:B0065956 name: DOCK2_HUMAN-Phosphotyrosine209 def: "Protein DOCK2_HUMAN with the residue 209 substituted with Phosphotyrosine" [UniProtKB:Q92608] xref: UniProtKB:Q92608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063281 ! DOCK2_HUMAN [Term] id: CCO:B0065957 name: DOCK2_HUMAN-Phosphotyrosine212 def: "Protein DOCK2_HUMAN with the residue 212 substituted with Phosphotyrosine" [UniProtKB:Q92608] xref: UniProtKB:Q92608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063281 ! DOCK2_HUMAN [Term] id: CCO:B0065958 name: DOCK2_HUMAN-Phosphoserine1706 def: "Protein DOCK2_HUMAN with the residue 1706 substituted with Phosphoserine" [UniProtKB:Q92608] comment: By similarity xref: UniProtKB:Q92608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0004518 ! Rac guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0005691 ! T cell receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063281 ! DOCK2_HUMAN [Term] id: CCO:B0065959 name: DPYL4_HUMAN-Phosphoserine544 def: "Protein DPYL4_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:O14531] xref: UniProtKB:O14531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063452 ! DPYL4_HUMAN [Term] id: CCO:B0065960 name: E41L3_HUMAN-Phosphoserine88 def: "Protein E41L3_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065961 name: E41L3_HUMAN-Phosphoserine443 def: "Protein E41L3_HUMAN with the residue 443 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065962 name: E41L3_HUMAN-Phosphoserine460 def: "Protein E41L3_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065963 name: E41L3_HUMAN-Phosphothreonine462 def: "Protein E41L3_HUMAN with the residue 462 substituted with Phosphothreonine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065964 name: E41L3_HUMAN-Phosphothreonine469 def: "Protein E41L3_HUMAN with the residue 469 substituted with Phosphothreonine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065965 name: E41L3_HUMAN-Phosphothreonine703 def: "Protein E41L3_HUMAN with the residue 703 substituted with Phosphothreonine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065966 name: E41L3_HUMAN-Phosphothreonine704 def: "Protein E41L3_HUMAN with the residue 704 substituted with Phosphothreonine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065967 name: E41L3_HUMAN-Phosphoserine708 def: "Protein E41L3_HUMAN with the residue 708 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065968 name: E41L3_HUMAN-Phosphoserine762 def: "Protein E41L3_HUMAN with the residue 762 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065969 name: E41L3_HUMAN-Phosphothreonine784 def: "Protein E41L3_HUMAN with the residue 784 substituted with Phosphothreonine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065970 name: E41L3_HUMAN-Phosphoserine787 def: "Protein E41L3_HUMAN with the residue 787 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065971 name: E41L3_HUMAN-Phosphoserine788 def: "Protein E41L3_HUMAN with the residue 788 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065972 name: E41L3_HUMAN-Phosphoserine962 def: "Protein E41L3_HUMAN with the residue 962 substituted with Phosphoserine" [UniProtKB:Q9Y2J2] xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065973 name: E41L3_HUMAN-Phosphothreonine1081 def: "Protein E41L3_HUMAN with the residue 1081 substituted with Phosphothreonine" [UniProtKB:Q9Y2J2] comment: By similarity xref: UniProtKB:Q9Y2J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:B0065974 name: ECH1_HUMAN-Phosphoserine28 def: "Protein ECH1_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q13011] xref: UniProtKB:Q13011 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063377 ! ECH1_HUMAN [Term] id: CCO:B0065975 name: ECH1_HUMAN-Phosphoserine30 def: "Protein ECH1_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q13011] xref: UniProtKB:Q13011 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000722 ! enoyl-CoA hydratase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000359 ! peroxisome relationship: transformation_of CCO:B0063377 ! ECH1_HUMAN [Term] id: CCO:B0065976 name: ECHA_HUMAN-N6-acetyllysine569 def: "Protein ECHA_HUMAN with the residue 569 substituted with N6-acetyllysine" [UniProtKB:P40939] comment: By similarity xref: UniProtKB:P40939 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063089 ! ECHA_HUMAN [Term] id: CCO:B0065977 name: ECHA_HUMAN-N6-acetyllysine728 def: "Protein ECHA_HUMAN with the residue 728 substituted with N6-acetyllysine" [UniProtKB:P40939] comment: By similarity xref: UniProtKB:P40939 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000016 ! acyl-CoA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000376 ! 3-hydroxyacyl-CoA dehydrogenase activity relationship: has_function CCO:F0000470 ! acetyl-CoA C-acetyltransferase activity relationship: has_function CCO:F0000473 ! acetyl-CoA C-acyltransferase activity relationship: has_function CCO:F0000722 ! enoyl-CoA hydratase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003187 ! long-chain-enoyl-CoA hydratase activity relationship: has_function CCO:F0003188 ! long-chain-3-hydroxyacyl-CoA dehydrogenase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0007988 ! coenzyme binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000797 ! fatty acid beta-oxidation multienzyme complex relationship: transformation_of CCO:B0063089 ! ECHA_HUMAN [Term] id: CCO:B0065978 name: ECHA_HUMAN-Phosphoserine756 def: "Protein ECHA_HUMAN with the residue 756 substituted with Phosphoserine" [UniProtKB:P40939] xref: UniProtKB:P40939 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063089 ! ECHA_HUMAN [Term] id: CCO:B0065979 name: ECHB_HUMAN-N6-acetyllysine201 def: "Protein ECHB_HUMAN with the residue 201 substituted with N6-acetyllysine" [UniProtKB:P55084] comment: By similarity xref: UniProtKB:P55084 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063084 ! ECHB_HUMAN [Term] id: CCO:B0065980 name: ECHB_HUMAN-N6-acetyllysine348 def: "Protein ECHB_HUMAN with the residue 348 substituted with N6-acetyllysine" [UniProtKB:P55084] comment: By similarity xref: UniProtKB:P55084 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000376 ! 3-hydroxyacyl-CoA dehydrogenase activity relationship: has_function CCO:F0000473 ! acetyl-CoA C-acyltransferase activity relationship: has_function CCO:F0000722 ! enoyl-CoA hydratase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000326 ! mitochondrial envelope relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0063084 ! ECHB_HUMAN [Term] id: CCO:B0065981 name: EF2_HUMAN-Phosphothreonine54 def: "Protein EF2_HUMAN with the residue 54 substituted with Phosphothreonine" [UniProtKB:P13639] comment: By similarity xref: UniProtKB:P13639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063182 ! EF2_HUMAN [Term] id: CCO:B0065982 name: EF2_HUMAN-Phosphothreonine57 def: "Protein EF2_HUMAN with the residue 57 substituted with Phosphothreonine" [UniProtKB:P13639] xref: UniProtKB:P13639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063182 ! EF2_HUMAN [Term] id: CCO:B0065983 name: EF2_HUMAN-Phosphothreonine59 def: "Protein EF2_HUMAN with the residue 59 substituted with Phosphothreonine" [UniProtKB:P13639] comment: By similarity xref: UniProtKB:P13639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063182 ! EF2_HUMAN [Term] id: CCO:B0065984 name: EF2_HUMAN-Phosphotyrosine265 def: "Protein EF2_HUMAN with the residue 265 substituted with Phosphotyrosine" [UniProtKB:P13639] xref: UniProtKB:P13639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063182 ! EF2_HUMAN [Term] id: CCO:B0065985 name: EF2_HUMAN-Phosphoserine502 def: "Protein EF2_HUMAN with the residue 502 substituted with Phosphoserine" [UniProtKB:P13639] xref: UniProtKB:P13639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063182 ! EF2_HUMAN [Term] id: CCO:B0065986 name: EF2_HUMAN-Diphthamide715 def: "Protein EF2_HUMAN with the residue 715 substituted with Diphthamide" [UniProtKB:P13639] xref: UniProtKB:P13639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063182 ! EF2_HUMAN [Term] id: CCO:B0065987 name: EHMT2_HUMAN-Phosphoserine173 def: "Protein EHMT2_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q96KQ7] xref: UniProtKB:Q96KQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:B0065988 name: EHMT2_HUMAN-Phosphothreonine1210 def: "Protein EHMT2_HUMAN with the residue 1210 substituted with Phosphothreonine" [UniProtKB:Q96KQ7] xref: UniProtKB:Q96KQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:B0065989 name: EIF3M_HUMAN-N-acetylserine2 def: "Protein EIF3M_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q7L2H7] xref: UniProtKB:Q7L2H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063407 ! EIF3M_HUMAN [Term] id: CCO:B0065990 name: EIF3M_HUMAN-Phosphoserine337 def: "Protein EIF3M_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q7L2H7] xref: UniProtKB:Q7L2H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063407 ! EIF3M_HUMAN [Term] id: CCO:B0065991 name: EIF3M_HUMAN-Phosphotyrosine351 def: "Protein EIF3M_HUMAN with the residue 351 substituted with Phosphotyrosine" [UniProtKB:Q7L2H7] xref: UniProtKB:Q7L2H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063407 ! EIF3M_HUMAN [Term] id: CCO:B0065992 name: EMD_HUMAN-Phosphoserine49 def: "Protein EMD_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:P50402] comment: by PKA; xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0065993 name: EMD_HUMAN-Phosphoserine52 def: "Protein EMD_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0065994 name: EMD_HUMAN-Phosphoserine54 def: "Protein EMD_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0065995 name: EMD_HUMAN-Phosphotyrosine59 def: "Protein EMD_HUMAN with the residue 59 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0065996 name: EMD_HUMAN-Phosphoserine60 def: "Protein EMD_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0065997 name: EMD_HUMAN-Phosphoserine66 def: "Protein EMD_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0065998 name: EMD_HUMAN-Phosphotyrosine74 def: "Protein EMD_HUMAN with the residue 74 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0065999 name: EMD_HUMAN-Phosphotyrosine85 def: "Protein EMD_HUMAN with the residue 85 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066000 name: EMD_HUMAN-Phosphoserine87 def: "Protein EMD_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066001 name: EMD_HUMAN-Phosphotyrosine95 def: "Protein EMD_HUMAN with the residue 95 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066002 name: EMD_HUMAN-Phosphotyrosine99 def: "Protein EMD_HUMAN with the residue 99 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066003 name: EMD_HUMAN-Phosphotyrosine105 def: "Protein EMD_HUMAN with the residue 105 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000254 ! nuclear inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066004 name: EMD_HUMAN-Phosphoserine120 def: "Protein EMD_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066005 name: EMD_HUMAN-Phosphotyrosine161 def: "Protein EMD_HUMAN with the residue 161 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066006 name: EMD_HUMAN-Phosphoserine163 def: "Protein EMD_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066007 name: EMD_HUMAN-Phosphotyrosine167 def: "Protein EMD_HUMAN with the residue 167 substituted with Phosphotyrosine" [UniProtKB:P50402] xref: UniProtKB:P50402 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:B0066008 name: ENOX1_HUMAN-Phosphoserine403 def: "Protein ENOX1_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:Q8TC92] comment: By similarity xref: UniProtKB:Q8TC92 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001644 ! copper ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0062800 ! ENOX1_HUMAN [Term] id: CCO:B0066009 name: EPN1_HUMAN-Phosphoserine357 def: "Protein EPN1_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q9Y6I3] comment: by CDC2; xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:B0066010 name: EPN1_HUMAN-Phosphoserine395 def: "Protein EPN1_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q9Y6I3] comment: By similarity xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:B0066011 name: EPN1_HUMAN-Phosphoserine410 def: "Protein EPN1_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q9Y6I3] xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:B0066012 name: EPN1_HUMAN-Phosphoserine429 def: "Protein EPN1_HUMAN with the residue 429 substituted with Phosphoserine" [UniProtKB:Q9Y6I3] xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:B0066013 name: EPN1_HUMAN-Phosphothreonine435 def: "Protein EPN1_HUMAN with the residue 435 substituted with Phosphothreonine" [UniProtKB:Q9Y6I3] xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:B0066014 name: EPN1_HUMAN-Phosphothreonine439 def: "Protein EPN1_HUMAN with the residue 439 substituted with Phosphothreonine" [UniProtKB:Q9Y6I3] xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:B0066015 name: EPN1_HUMAN-Phosphothreonine469 def: "Protein EPN1_HUMAN with the residue 469 substituted with Phosphothreonine" [UniProtKB:Q9Y6I3] xref: UniProtKB:Q9Y6I3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:B0066016 name: EPN4_HUMAN-Phosphoserine22 def: "Protein EPN4_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066017 name: EPN4_HUMAN-Phosphoserine26 def: "Protein EPN4_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066018 name: EPN4_HUMAN-Phosphoserine163 def: "Protein EPN4_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:Q14677] comment: By similarity xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066019 name: EPN4_HUMAN-Phosphoserine227 def: "Protein EPN4_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066020 name: EPN4_HUMAN-Phosphoserine232 def: "Protein EPN4_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066021 name: EPN4_HUMAN-Phosphoserine234 def: "Protein EPN4_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066022 name: EPN4_HUMAN-Phosphoserine245 def: "Protein EPN4_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066023 name: EPN4_HUMAN-Phosphothreonine272 def: "Protein EPN4_HUMAN with the residue 272 substituted with Phosphothreonine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066024 name: EPN4_HUMAN-Phosphoserine299 def: "Protein EPN4_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:Q14677] xref: UniProtKB:Q14677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063201 ! EPN4_HUMAN [Term] id: CCO:B0066025 name: ERG19_HUMAN-Phosphoserine96 def: "Protein ERG19_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:P53602] xref: UniProtKB:P53602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000634 ! diphosphomevalonate decarboxylase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0025709 ! ERG19_HUMAN [Term] id: CCO:B0066026 name: ESYT1_HUMAN-Phosphotyrosine822 def: "Protein ESYT1_HUMAN with the residue 822 substituted with Phosphotyrosine" [UniProtKB:Q9BSJ8] xref: UniProtKB:Q9BSJ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063068 ! ESYT1_HUMAN [Term] id: CCO:B0066027 name: ESYT1_HUMAN-Phosphoserine963 def: "Protein ESYT1_HUMAN with the residue 963 substituted with Phosphoserine" [UniProtKB:Q9BSJ8] xref: UniProtKB:Q9BSJ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063068 ! ESYT1_HUMAN [Term] id: CCO:B0066028 name: ESYT1_HUMAN-Phosphotyrosine1009 def: "Protein ESYT1_HUMAN with the residue 1009 substituted with Phosphotyrosine" [UniProtKB:Q9BSJ8] xref: UniProtKB:Q9BSJ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063068 ! ESYT1_HUMAN [Term] id: CCO:B0066029 name: ESYT1_HUMAN-Phosphoserine1034 def: "Protein ESYT1_HUMAN with the residue 1034 substituted with Phosphoserine" [UniProtKB:Q9BSJ8] xref: UniProtKB:Q9BSJ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063068 ! ESYT1_HUMAN [Term] id: CCO:B0066030 name: EXOC2_HUMAN-Phosphoserine432 def: "Protein EXOC2_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:Q96KP1] xref: UniProtKB:Q96KP1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003600 ! Ral GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063296 ! EXOC2_HUMAN [Term] id: CCO:B0066031 name: EXOC2_HUMAN-Phosphoserine435 def: "Protein EXOC2_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:Q96KP1] comment: By similarity xref: UniProtKB:Q96KP1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063296 ! EXOC2_HUMAN [Term] id: CCO:B0066032 name: EXOC4_HUMAN-Phosphothreonine237 def: "Protein EXOC4_HUMAN with the residue 237 substituted with Phosphothreonine" [UniProtKB:Q96A65] xref: UniProtKB:Q96A65 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000024 ! exocyst relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063049 ! EXOC4_HUMAN [Term] id: CCO:B0066033 name: EXOC7_HUMAN-Phosphoserine250 def: "Protein EXOC7_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:Q9UPT5] xref: UniProtKB:Q9UPT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062769 ! EXOC7_HUMAN [Term] id: CCO:B0066034 name: F103A_HUMAN-Phosphoserine36 def: "Protein F103A_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q9BTL3] xref: UniProtKB:Q9BTL3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062856 ! F103A_HUMAN [Term] id: CCO:B0066035 name: F10A1_HUMAN-Phosphoserine75 def: "Protein F10A1_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:P50502] xref: UniProtKB:P50502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063106 ! F10A1_HUMAN [Term] id: CCO:B0066036 name: F10A1_HUMAN-Phosphoserine76 def: "Protein F10A1_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:P50502] xref: UniProtKB:P50502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063106 ! F10A1_HUMAN [Term] id: CCO:B0066037 name: F10A1_HUMAN-Phosphoserine79 def: "Protein F10A1_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:P50502] xref: UniProtKB:P50502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063106 ! F10A1_HUMAN [Term] id: CCO:B0066038 name: F10A1_HUMAN-Phosphoserine181 def: "Protein F10A1_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:P50502] xref: UniProtKB:P50502 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063106 ! F10A1_HUMAN [Term] id: CCO:B0066039 name: F10A4_HUMAN-Phosphoserine71 def: "Protein F10A4_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q8IZP2] xref: UniProtKB:Q8IZP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063115 ! F10A4_HUMAN [Term] id: CCO:B0066040 name: F10A4_HUMAN-Phosphoserine72 def: "Protein F10A4_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:Q8IZP2] xref: UniProtKB:Q8IZP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063115 ! F10A4_HUMAN [Term] id: CCO:B0066041 name: F10A4_HUMAN-Phosphoserine75 def: "Protein F10A4_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q8IZP2] xref: UniProtKB:Q8IZP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063115 ! F10A4_HUMAN [Term] id: CCO:B0066042 name: F10C1_HUMAN-Phosphoserine12 def: "Protein F10C1_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q70Z53] comment: By similarity xref: UniProtKB:Q70Z53 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:B0066043 name: F10C1_HUMAN-Phosphoserine251 def: "Protein F10C1_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:Q70Z53] xref: UniProtKB:Q70Z53 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:B0066044 name: F10C1_HUMAN-Phosphoserine252 def: "Protein F10C1_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:Q70Z53] xref: UniProtKB:Q70Z53 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:B0066045 name: F10C1_HUMAN-Phosphoserine283 def: "Protein F10C1_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q70Z53] comment: By similarity xref: UniProtKB:Q70Z53 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:B0066046 name: F10C1_HUMAN-Phosphoserine285 def: "Protein F10C1_HUMAN with the residue 285 substituted with Phosphoserine" [UniProtKB:Q70Z53] comment: By similarity xref: UniProtKB:Q70Z53 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:B0066047 name: F120A_HUMAN-Phosphoserine30 def: "Protein F120A_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q9NZB2] xref: UniProtKB:Q9NZB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062987 ! F120A_HUMAN [Term] id: CCO:B0066048 name: F120A_HUMAN-Phosphoserine383 def: "Protein F120A_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q9NZB2] xref: UniProtKB:Q9NZB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062987 ! F120A_HUMAN [Term] id: CCO:B0066049 name: F120A_HUMAN-Phosphotyrosine393 def: "Protein F120A_HUMAN with the residue 393 substituted with Phosphotyrosine" [UniProtKB:Q9NZB2] xref: UniProtKB:Q9NZB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062987 ! F120A_HUMAN [Term] id: CCO:B0066050 name: F120A_HUMAN-Phosphotyrosine395 def: "Protein F120A_HUMAN with the residue 395 substituted with Phosphotyrosine" [UniProtKB:Q9NZB2] xref: UniProtKB:Q9NZB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062987 ! F120A_HUMAN [Term] id: CCO:B0066051 name: F120A_HUMAN-Omega-N-methylated arginine982 def: "Protein F120A_HUMAN with the residue 982 substituted with Omega-N-methylated arginine" [UniProtKB:Q9NZB2] xref: UniProtKB:Q9NZB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062987 ! F120A_HUMAN [Term] id: CCO:B0066052 name: F120A_HUMAN-Phosphothreonine991 def: "Protein F120A_HUMAN with the residue 991 substituted with Phosphothreonine" [UniProtKB:Q9NZB2] xref: UniProtKB:Q9NZB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062987 ! F120A_HUMAN [Term] id: CCO:B0066053 name: F120A_HUMAN-Phosphoserine1023 def: "Protein F120A_HUMAN with the residue 1023 substituted with Phosphoserine" [UniProtKB:Q9NZB2] xref: UniProtKB:Q9NZB2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062987 ! F120A_HUMAN [Term] id: CCO:B0066054 name: F134A_HUMAN-Phosphothreonine279 def: "Protein F134A_HUMAN with the residue 279 substituted with Phosphothreonine" [UniProtKB:Q8NC44] xref: UniProtKB:Q8NC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:B0066055 name: F134A_HUMAN-Phosphoserine281 def: "Protein F134A_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q8NC44] xref: UniProtKB:Q8NC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:B0066056 name: F134A_HUMAN-Phosphoserine283 def: "Protein F134A_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q8NC44] xref: UniProtKB:Q8NC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:B0066057 name: F134A_HUMAN-Phosphothreonine306 def: "Protein F134A_HUMAN with the residue 306 substituted with Phosphothreonine" [UniProtKB:Q8NC44] xref: UniProtKB:Q8NC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:B0066058 name: F134A_HUMAN-Phosphoserine308 def: "Protein F134A_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:Q8NC44] xref: UniProtKB:Q8NC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:B0066059 name: F134A_HUMAN-Phosphoserine311 def: "Protein F134A_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q8NC44] xref: UniProtKB:Q8NC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:B0066060 name: F134A_HUMAN-Phosphoserine385 def: "Protein F134A_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:Q8NC44] xref: UniProtKB:Q8NC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:B0066061 name: F16P2_HUMAN-Phosphotyrosine216 def: "Protein F16P2_HUMAN with the residue 216 substituted with Phosphotyrosine" [UniProtKB:O00757] xref: UniProtKB:O00757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000750 ! fructose-2,6-bisphosphate 2-phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005685 ! phosphoric ester hydrolase activity relationship: has_function CCO:F0008485 ! fructose 1,6-bisphosphate 1-phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0043612 ! F16P2_HUMAN [Term] id: CCO:B0066062 name: FA10_HUMAN-4-carboxyglutamate46 def: "Protein FA10_HUMAN with the residue 46 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066063 name: FA10_HUMAN-4-carboxyglutamate47 def: "Protein FA10_HUMAN with the residue 47 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066064 name: FA10_HUMAN-4-carboxyglutamate54 def: "Protein FA10_HUMAN with the residue 54 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066065 name: FA10_HUMAN-4-carboxyglutamate56 def: "Protein FA10_HUMAN with the residue 56 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066066 name: FA10_HUMAN-4-carboxyglutamate59 def: "Protein FA10_HUMAN with the residue 59 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066067 name: FA10_HUMAN-4-carboxyglutamate60 def: "Protein FA10_HUMAN with the residue 60 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066068 name: FA10_HUMAN-4-carboxyglutamate65 def: "Protein FA10_HUMAN with the residue 65 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066069 name: FA10_HUMAN-4-carboxyglutamate66 def: "Protein FA10_HUMAN with the residue 66 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066070 name: FA10_HUMAN-4-carboxyglutamate69 def: "Protein FA10_HUMAN with the residue 69 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066071 name: FA10_HUMAN-4-carboxyglutamate72 def: "Protein FA10_HUMAN with the residue 72 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066072 name: FA10_HUMAN-4-carboxyglutamate79 def: "Protein FA10_HUMAN with the residue 79 substituted with 4-carboxyglutamate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000329 ! coagulation factor Xa activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066073 name: FA10_HUMAN-3-hydroxyaspartate103 def: "Protein FA10_HUMAN with the residue 103 substituted with 3-hydroxyaspartate" [UniProtKB:P00742] xref: UniProtKB:P00742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:B0066074 name: FA21C_HUMAN-Phosphoserine158 def: "Protein FA21C_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066075 name: FA21C_HUMAN-Phosphoserine160 def: "Protein FA21C_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066076 name: FA21C_HUMAN-Phosphoserine230 def: "Protein FA21C_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066077 name: FA21C_HUMAN-Phosphoserine238 def: "Protein FA21C_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066078 name: FA21C_HUMAN-Phosphoserine250 def: "Protein FA21C_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066079 name: FA21C_HUMAN-Phosphoserine265 def: "Protein FA21C_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066080 name: FA21C_HUMAN-Phosphoserine284 def: "Protein FA21C_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066081 name: FA21C_HUMAN-Phosphothreonine287 def: "Protein FA21C_HUMAN with the residue 287 substituted with Phosphothreonine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066082 name: FA21C_HUMAN-Phosphoserine288 def: "Protein FA21C_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066083 name: FA21C_HUMAN-Phosphothreonine331 def: "Protein FA21C_HUMAN with the residue 331 substituted with Phosphothreonine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066084 name: FA21C_HUMAN-Phosphoserine333 def: "Protein FA21C_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066085 name: FA21C_HUMAN-Phosphoserine352 def: "Protein FA21C_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066086 name: FA21C_HUMAN-Phosphoserine356 def: "Protein FA21C_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066087 name: FA21C_HUMAN-Phosphoserine441 def: "Protein FA21C_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066088 name: FA21C_HUMAN-Phosphoserine498 def: "Protein FA21C_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066089 name: FA21C_HUMAN-Phosphothreonine502 def: "Protein FA21C_HUMAN with the residue 502 substituted with Phosphothreonine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066090 name: FA21C_HUMAN-Phosphoserine504 def: "Protein FA21C_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066091 name: FA21C_HUMAN-Phosphoserine539 def: "Protein FA21C_HUMAN with the residue 539 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066092 name: FA21C_HUMAN-Phosphoserine619 def: "Protein FA21C_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066093 name: FA21C_HUMAN-Phosphoserine620 def: "Protein FA21C_HUMAN with the residue 620 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066094 name: FA21C_HUMAN-Phosphoserine752 def: "Protein FA21C_HUMAN with the residue 752 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] comment: By similarity xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066095 name: FA21C_HUMAN-Phosphothreonine797 def: "Protein FA21C_HUMAN with the residue 797 substituted with Phosphothreonine" [UniProtKB:Q9Y4E1] comment: By similarity xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066096 name: FA21C_HUMAN-Phosphothreonine799 def: "Protein FA21C_HUMAN with the residue 799 substituted with Phosphothreonine" [UniProtKB:Q9Y4E1] comment: By similarity xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066097 name: FA21C_HUMAN-Phosphoserine802 def: "Protein FA21C_HUMAN with the residue 802 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] comment: By similarity xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066098 name: FA21C_HUMAN-Phosphoserine874 def: "Protein FA21C_HUMAN with the residue 874 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] comment: By similarity xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066099 name: FA21C_HUMAN-Phosphoserine1033 def: "Protein FA21C_HUMAN with the residue 1033 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] comment: By similarity xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066100 name: FA21C_HUMAN-Phosphoserine1054 def: "Protein FA21C_HUMAN with the residue 1054 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066101 name: FA21C_HUMAN-Phosphoserine1158 def: "Protein FA21C_HUMAN with the residue 1158 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066102 name: FA21C_HUMAN-Phosphoserine1159 def: "Protein FA21C_HUMAN with the residue 1159 substituted with Phosphoserine" [UniProtKB:Q9Y4E1] xref: UniProtKB:Q9Y4E1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:B0066103 name: FA7_HUMAN-4-carboxyglutamate66 def: "Protein FA7_HUMAN with the residue 66 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066104 name: FA7_HUMAN-4-carboxyglutamate67 def: "Protein FA7_HUMAN with the residue 67 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066105 name: FA7_HUMAN-4-carboxyglutamate74 def: "Protein FA7_HUMAN with the residue 74 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066106 name: FA7_HUMAN-4-carboxyglutamate76 def: "Protein FA7_HUMAN with the residue 76 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066107 name: FA7_HUMAN-4-carboxyglutamate79 def: "Protein FA7_HUMAN with the residue 79 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066108 name: FA7_HUMAN-4-carboxyglutamate80 def: "Protein FA7_HUMAN with the residue 80 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066109 name: FA7_HUMAN-4-carboxyglutamate85 def: "Protein FA7_HUMAN with the residue 85 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000327 ! coagulation factor VIIa activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001786 ! serine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066110 name: FA7_HUMAN-4-carboxyglutamate86 def: "Protein FA7_HUMAN with the residue 86 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066111 name: FA7_HUMAN-4-carboxyglutamate89 def: "Protein FA7_HUMAN with the residue 89 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066112 name: FA7_HUMAN-4-carboxyglutamate95 def: "Protein FA7_HUMAN with the residue 95 substituted with 4-carboxyglutamate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066113 name: FA7_HUMAN-3-hydroxyaspartate123 def: "Protein FA7_HUMAN with the residue 123 substituted with 3-hydroxyaspartate" [UniProtKB:P08709] xref: UniProtKB:P08709 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:B0066114 name: FAF1_HUMAN-Phosphoserine320 def: "Protein FAF1_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q9UNN5] xref: UniProtKB:Q9UNN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059254 ! FAF1_HUMAN [Term] id: CCO:B0066115 name: FAF1_HUMAN-Phosphothreonine580 def: "Protein FAF1_HUMAN with the residue 580 substituted with Phosphothreonine" [UniProtKB:Q9UNN5] comment: By similarity xref: UniProtKB:Q9UNN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002008 ! protein kinase CK2 regulator activity relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004344 ! Hsp70/Hsc70 protein inhibitor activity relationship: has_function CCO:F0004628 ! heat shock protein binding relationship: has_function CCO:F0008045 ! NF-kappaB binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001184 ! CD95 death-inducing signaling complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0059254 ! FAF1_HUMAN [Term] id: CCO:B0066116 name: FAIM2_HUMAN-Phosphotyrosine38 def: "Protein FAIM2_HUMAN with the residue 38 substituted with Phosphotyrosine" [UniProtKB:Q9BWQ8] comment: By similarity xref: UniProtKB:Q9BWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0058535 ! FAIM2_HUMAN [Term] id: CCO:B0066117 name: FAK1_HUMAN-Phosphotyrosine570 def: "Protein FAK1_HUMAN with the residue 570 substituted with Phosphotyrosine" [UniProtKB:Q05397] xref: UniProtKB:Q05397 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:B0066118 name: FANCE_HUMAN-Phosphoserine249 def: "Protein FANCE_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q9HB96] xref: UniProtKB:Q9HB96 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005576 ! FANCE_HUMAN [Term] id: CCO:B0066119 name: FANCJ_HUMAN-Phosphothreonine918 def: "Protein FANCJ_HUMAN with the residue 918 substituted with Phosphothreonine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000487 ! ATP-dependent DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0066120 name: FANCJ_HUMAN-Phosphotyrosine921 def: "Protein FANCJ_HUMAN with the residue 921 substituted with Phosphotyrosine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0066121 name: FANCJ_HUMAN-Phosphoserine927 def: "Protein FANCJ_HUMAN with the residue 927 substituted with Phosphoserine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0066122 name: FANCJ_HUMAN-Phosphoserine930 def: "Protein FANCJ_HUMAN with the residue 930 substituted with Phosphoserine" [UniProtKB:Q9BX63] xref: UniProtKB:Q9BX63 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002107 ! FANCJ_HUMAN [Term] id: CCO:B0066123 name: FARP1_HUMAN-Phosphothreonine24 def: "Protein FARP1_HUMAN with the residue 24 substituted with Phosphothreonine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066124 name: FARP1_HUMAN-Phosphoserine336 def: "Protein FARP1_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066125 name: FARP1_HUMAN-Phosphoserine340 def: "Protein FARP1_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066126 name: FARP1_HUMAN-Phosphoserine427 def: "Protein FARP1_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066127 name: FARP1_HUMAN-Phosphoserine889 def: "Protein FARP1_HUMAN with the residue 889 substituted with Phosphoserine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066128 name: FARP1_HUMAN-Phosphoserine896 def: "Protein FARP1_HUMAN with the residue 896 substituted with Phosphoserine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066129 name: FARP1_HUMAN-Phosphothreonine898 def: "Protein FARP1_HUMAN with the residue 898 substituted with Phosphothreonine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066130 name: FARP1_HUMAN-Phosphoserine899 def: "Protein FARP1_HUMAN with the residue 899 substituted with Phosphoserine" [UniProtKB:Q9Y4F1] xref: UniProtKB:Q9Y4F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059360 ! FARP1_HUMAN [Term] id: CCO:B0066131 name: FARP2_HUMAN-Phosphoserine375 def: "Protein FARP2_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:O94887] comment: By similarity xref: UniProtKB:O94887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054705 ! FARP2_HUMAN [Term] id: CCO:B0066132 name: FARP2_HUMAN-Phosphoserine876 def: "Protein FARP2_HUMAN with the residue 876 substituted with Phosphoserine" [UniProtKB:O94887] comment: By similarity xref: UniProtKB:O94887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054705 ! FARP2_HUMAN [Term] id: CCO:B0066133 name: FARP2_HUMAN-Phosphoserine881 def: "Protein FARP2_HUMAN with the residue 881 substituted with Phosphoserine" [UniProtKB:O94887] comment: By similarity xref: UniProtKB:O94887 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000900 ! extrinsic to membrane relationship: transformation_of CCO:B0054705 ! FARP2_HUMAN [Term] id: CCO:B0066134 name: FAS_HUMAN-N-acetylmethionine1 def: "Protein FAS_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P49327] xref: UniProtKB:P49327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000733 ! fatty-acid synthase activity relationship: has_function CCO:F0000736 ! 3-oxoacyl-[acyl-carrier-protein] synthase activity relationship: has_function CCO:F0000737 ! 3-oxoacyl-[acyl-carrier-protein] reductase activity relationship: has_function CCO:F0000738 ! 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity relationship: has_function CCO:F0000740 ! enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity relationship: has_function CCO:F0000741 ! oleoyl-[acyl-carrier-protein] hydrolase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003360 ! hydrolase activity, acting on ester bonds relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0004104 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity relationship: has_function CCO:F0004637 ! phosphopantetheine binding relationship: has_function CCO:F0007309 ! cofactor binding relationship: has_function CCO:F0008251 ! [acyl-carrier-protein] S-acetyltransferase activity relationship: has_function CCO:F0008252 ! [acyl-carrier-protein] S-malonyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0001659 ! glycogen granule relationship: transformation_of CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:B0066135 name: FAS_HUMAN-Phosphoserine207 def: "Protein FAS_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:P49327] xref: UniProtKB:P49327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:B0066136 name: FAS_HUMAN-Phosphoserine2198 def: "Protein FAS_HUMAN with the residue 2198 substituted with Phosphoserine" [UniProtKB:P49327] xref: UniProtKB:P49327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:B0066137 name: FAS_HUMAN-Phosphothreonine2204 def: "Protein FAS_HUMAN with the residue 2204 substituted with Phosphothreonine" [UniProtKB:P49327] xref: UniProtKB:P49327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:B0066138 name: FAS_HUMAN-Phosphoserine2236 def: "Protein FAS_HUMAN with the residue 2236 substituted with Phosphoserine" [UniProtKB:P49327] xref: UniProtKB:P49327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:B0066139 name: FAT1_HUMAN-Phosphothreonine152 def: "Protein FAT1_HUMAN with the residue 152 substituted with Phosphothreonine" [UniProtKB:Q14517] xref: UniProtKB:Q14517 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062991 ! FAT1_HUMAN [Term] id: CCO:B0066140 name: FAT1_HUMAN-Phosphothreonine464 def: "Protein FAT1_HUMAN with the residue 464 substituted with Phosphothreonine" [UniProtKB:Q14517] xref: UniProtKB:Q14517 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062991 ! FAT1_HUMAN [Term] id: CCO:B0066141 name: FAT1_HUMAN-Phosphotyrosine468 def: "Protein FAT1_HUMAN with the residue 468 substituted with Phosphotyrosine" [UniProtKB:Q14517] xref: UniProtKB:Q14517 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062991 ! FAT1_HUMAN [Term] id: CCO:B0066142 name: FAT1_HUMAN-Phosphotyrosine2604 def: "Protein FAT1_HUMAN with the residue 2604 substituted with Phosphotyrosine" [UniProtKB:Q14517] xref: UniProtKB:Q14517 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062991 ! FAT1_HUMAN [Term] id: CCO:B0066143 name: FAT1_HUMAN-Phosphoserine2611 def: "Protein FAT1_HUMAN with the residue 2611 substituted with Phosphoserine" [UniProtKB:Q14517] xref: UniProtKB:Q14517 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000989 ! filopodium relationship: transformation_of CCO:B0062991 ! FAT1_HUMAN [Term] id: CCO:B0066144 name: FAT1_HUMAN-Phosphothreonine2616 def: "Protein FAT1_HUMAN with the residue 2616 substituted with Phosphothreonine" [UniProtKB:Q14517] xref: UniProtKB:Q14517 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062991 ! FAT1_HUMAN [Term] id: CCO:B0066145 name: FAT1_HUMAN-Phosphoserine4274 def: "Protein FAT1_HUMAN with the residue 4274 substituted with Phosphoserine" [UniProtKB:Q14517] xref: UniProtKB:Q14517 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062991 ! FAT1_HUMAN [Term] id: CCO:B0066146 name: FBX28_HUMAN-Phosphoserine235 def: "Protein FBX28_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q9NVF7] xref: UniProtKB:Q9NVF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062771 ! FBX28_HUMAN [Term] id: CCO:B0066147 name: FBX28_HUMAN-Phosphoserine344 def: "Protein FBX28_HUMAN with the residue 344 substituted with Phosphoserine" [UniProtKB:Q9NVF7] xref: UniProtKB:Q9NVF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062771 ! FBX28_HUMAN [Term] id: CCO:B0066148 name: FCERG_HUMAN-Phosphotyrosine65 def: "Protein FCERG_HUMAN with the residue 65 substituted with Phosphotyrosine" [UniProtKB:P30273] xref: UniProtKB:P30273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055217 ! FCERG_HUMAN [Term] id: CCO:B0066149 name: FCERG_HUMAN-Phosphotyrosine76 def: "Protein FCERG_HUMAN with the residue 76 substituted with Phosphotyrosine" [UniProtKB:P30273] xref: UniProtKB:P30273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004152 ! IgE receptor activity relationship: has_function CCO:F0004196 ! IgE binding relationship: has_function CCO:F0004197 ! IgG binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001498 ! Fc-epsilon receptor I complex relationship: transformation_of CCO:B0055217 ! FCERG_HUMAN [Term] id: CCO:B0066150 name: FCERG_HUMAN-Phosphothreonine78 def: "Protein FCERG_HUMAN with the residue 78 substituted with Phosphothreonine" [UniProtKB:P30273] comment: By similarity xref: UniProtKB:P30273 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055217 ! FCERG_HUMAN [Term] id: CCO:B0066151 name: FCGR1_HUMAN-Phosphotyrosine133 def: "Protein FCGR1_HUMAN with the residue 133 substituted with Phosphotyrosine" [UniProtKB:P12314] xref: UniProtKB:P12314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042824 ! FCGR1_HUMAN [Term] id: CCO:B0066152 name: FCGR1_HUMAN-Phosphotyrosine138 def: "Protein FCGR1_HUMAN with the residue 138 substituted with Phosphotyrosine" [UniProtKB:P12314] xref: UniProtKB:P12314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0004197 ! IgG binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0042824 ! FCGR1_HUMAN [Term] id: CCO:B0066153 name: FCN2_HUMAN-Hydroxyproline77 def: "Protein FCN2_HUMAN with the residue 77 substituted with Hydroxyproline" [UniProtKB:Q15485] xref: UniProtKB:Q15485 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020112 ! FCN2_HUMAN [Term] id: CCO:B0066154 name: FCN2_HUMAN-Hydroxyproline80 def: "Protein FCN2_HUMAN with the residue 80 substituted with Hydroxyproline" [UniProtKB:Q15485] xref: UniProtKB:Q15485 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020112 ! FCN2_HUMAN [Term] id: CCO:B0066155 name: FCN2_HUMAN-Hydroxyproline86 def: "Protein FCN2_HUMAN with the residue 86 substituted with Hydroxyproline" [UniProtKB:Q15485] xref: UniProtKB:Q15485 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0020112 ! FCN2_HUMAN [Term] id: CCO:B0066156 name: FCN3_HUMAN-Hydroxyproline50 def: "Protein FCN3_HUMAN with the residue 50 substituted with Hydroxyproline" [UniProtKB:O75636] xref: UniProtKB:O75636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054661 ! FCN3_HUMAN [Term] id: CCO:B0066157 name: FCN3_HUMAN-Hydroxyproline53 def: "Protein FCN3_HUMAN with the residue 53 substituted with Hydroxyproline" [UniProtKB:O75636] xref: UniProtKB:O75636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054661 ! FCN3_HUMAN [Term] id: CCO:B0066158 name: FCN3_HUMAN-Hydroxyproline59 def: "Protein FCN3_HUMAN with the residue 59 substituted with Hydroxyproline" [UniProtKB:O75636] xref: UniProtKB:O75636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054661 ! FCN3_HUMAN [Term] id: CCO:B0066159 name: FCN3_HUMAN-Hydroxyproline65 def: "Protein FCN3_HUMAN with the residue 65 substituted with Hydroxyproline" [UniProtKB:O75636] xref: UniProtKB:O75636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054661 ! FCN3_HUMAN [Term] id: CCO:B0066160 name: FCN3_HUMAN-Hydroxyproline68 def: "Protein FCN3_HUMAN with the residue 68 substituted with Hydroxyproline" [UniProtKB:O75636] xref: UniProtKB:O75636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: transformation_of CCO:B0054661 ! FCN3_HUMAN [Term] id: CCO:B0066161 name: FCN3_HUMAN-Hydroxyproline77 def: "Protein FCN3_HUMAN with the residue 77 substituted with Hydroxyproline" [UniProtKB:O75636] xref: UniProtKB:O75636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054661 ! FCN3_HUMAN [Term] id: CCO:B0066162 name: FERM2_HUMAN-Phosphoserine159 def: "Protein FERM2_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:Q96AC1] xref: UniProtKB:Q96AC1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058150 ! FERM2_HUMAN [Term] id: CCO:B0066163 name: FERM2_HUMAN-Phosphoserine181 def: "Protein FERM2_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q96AC1] xref: UniProtKB:Q96AC1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001356 ! filamentous actin relationship: transformation_of CCO:B0058150 ! FERM2_HUMAN [Term] id: CCO:B0066164 name: FERM2_HUMAN-Phosphoserine666 def: "Protein FERM2_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:Q96AC1] xref: UniProtKB:Q96AC1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058150 ! FERM2_HUMAN [Term] id: CCO:B0066165 name: FER_HUMAN-Phosphotyrosine402 def: "Protein FER_HUMAN with the residue 402 substituted with Phosphotyrosine" [UniProtKB:P16591] xref: UniProtKB:P16591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055057 ! FER_HUMAN [Term] id: CCO:B0066166 name: FER_HUMAN-Phosphoserine434 def: "Protein FER_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:P16591] xref: UniProtKB:P16591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055057 ! FER_HUMAN [Term] id: CCO:B0066167 name: FER_HUMAN-Phosphotyrosine714 def: "Protein FER_HUMAN with the residue 714 substituted with Phosphotyrosine" [UniProtKB:P16591] comment: by autocatalysis; xref: UniProtKB:P16591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055057 ! FER_HUMAN [Term] id: CCO:B0066168 name: FES_HUMAN-Phosphotyrosine713 def: "Protein FES_HUMAN with the residue 713 substituted with Phosphotyrosine" [UniProtKB:P07332] comment: by autocatalysis; By similarity xref: UniProtKB:P07332 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054911 ! FES_HUMAN [Term] id: CCO:B0066169 name: FETUA_HUMAN-Phosphoserine138 def: "Protein FETUA_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:P02765] xref: UniProtKB:P02765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054873 ! FETUA_HUMAN [Term] id: CCO:B0066170 name: FETUA_HUMAN-Phosphoserine325 def: "Protein FETUA_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:P02765] comment: By similarity xref: UniProtKB:P02765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054873 ! FETUA_HUMAN [Term] id: CCO:B0066171 name: FETUA_HUMAN-Phosphoserine328 def: "Protein FETUA_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P02765] comment: By similarity xref: UniProtKB:P02765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054873 ! FETUA_HUMAN [Term] id: CCO:B0066172 name: FETUA_HUMAN-Phosphoserine330 def: "Protein FETUA_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P02765] xref: UniProtKB:P02765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0004133 ! kinase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: transformation_of CCO:B0054873 ! FETUA_HUMAN [Term] id: CCO:B0066173 name: FFAR1_HUMAN-Phosphotyrosine44 def: "Protein FFAR1_HUMAN with the residue 44 substituted with Phosphotyrosine" [UniProtKB:O14842] comment: By similarity xref: UniProtKB:O14842 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054382 ! FFAR1_HUMAN [Term] id: CCO:B0066174 name: FGD1_HUMAN-Phosphoserine48 def: "Protein FGD1_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:P98174] xref: UniProtKB:P98174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055676 ! FGD1_HUMAN [Term] id: CCO:B0066175 name: FGD1_HUMAN-Phosphoserine205 def: "Protein FGD1_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:P98174] xref: UniProtKB:P98174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055676 ! FGD1_HUMAN [Term] id: CCO:B0066176 name: FGD1_HUMAN-Phosphothreonine704 def: "Protein FGD1_HUMAN with the residue 704 substituted with Phosphothreonine" [UniProtKB:P98174] xref: UniProtKB:P98174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055676 ! FGD1_HUMAN [Term] id: CCO:B0066177 name: FGD1_HUMAN-Phosphothreonine711 def: "Protein FGD1_HUMAN with the residue 711 substituted with Phosphothreonine" [UniProtKB:P98174] xref: UniProtKB:P98174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004648 ! small GTPase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0055676 ! FGD1_HUMAN [Term] id: CCO:B0066178 name: FGD1_HUMAN-Phosphoserine715 def: "Protein FGD1_HUMAN with the residue 715 substituted with Phosphoserine" [UniProtKB:P98174] xref: UniProtKB:P98174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055676 ! FGD1_HUMAN [Term] id: CCO:B0066179 name: FGD3_HUMAN-Phosphoserine128 def: "Protein FGD3_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:Q5JSP0] xref: UniProtKB:Q5JSP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004648 ! small GTPase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: transformation_of CCO:B0056480 ! FGD3_HUMAN [Term] id: CCO:B0066180 name: FGD5_HUMAN-Phosphoserine632 def: "Protein FGD5_HUMAN with the residue 632 substituted with Phosphoserine" [UniProtKB:Q6ZNL6] comment: By similarity xref: UniProtKB:Q6ZNL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057029 ! FGD5_HUMAN [Term] id: CCO:B0066181 name: FGD5_HUMAN-Phosphoserine635 def: "Protein FGD5_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:Q6ZNL6] comment: By similarity xref: UniProtKB:Q6ZNL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057029 ! FGD5_HUMAN [Term] id: CCO:B0066182 name: FGD6_HUMAN-Phosphoserine515 def: "Protein FGD6_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:Q6ZV73] xref: UniProtKB:Q6ZV73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057083 ! FGD6_HUMAN [Term] id: CCO:B0066183 name: FGD6_HUMAN-Phosphoserine721 def: "Protein FGD6_HUMAN with the residue 721 substituted with Phosphoserine" [UniProtKB:Q6ZV73] xref: UniProtKB:Q6ZV73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004648 ! small GTPase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: transformation_of CCO:B0057083 ! FGD6_HUMAN [Term] id: CCO:B0066184 name: FGFR1_HUMAN-Phosphotyrosine653 def: "Protein FGFR1_HUMAN with the residue 653 substituted with Phosphotyrosine" [UniProtKB:P11362] xref: UniProtKB:P11362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005868 ! FGFR1_HUMAN [Term] id: CCO:B0066185 name: FGFR4_HUMAN-Phosphotyrosine643 def: "Protein FGFR4_HUMAN with the residue 643 substituted with Phosphotyrosine" [UniProtKB:P22455] comment: by autocatalysis; By similarity xref: UniProtKB:P22455 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055147 ! FGFR4_HUMAN [Term] id: CCO:B0066186 name: FHL2_HUMAN-Phosphoserine238 def: "Protein FHL2_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q14192] xref: UniProtKB:Q14192 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005830 ! FHL2_HUMAN [Term] id: CCO:B0066187 name: FIBA_HUMAN-Phosphoserine22 def: "Protein FIBA_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:P02671] xref: UniProtKB:P02671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:B0066188 name: FIBA_HUMAN-Phosphotyrosine277 def: "Protein FIBA_HUMAN with the residue 277 substituted with Phosphotyrosine" [UniProtKB:P02671] xref: UniProtKB:P02671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:B0066189 name: FIBA_HUMAN-Phosphoserine364 def: "Protein FIBA_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:P02671] xref: UniProtKB:P02671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000202 ! fibrinogen complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001130 ! platelet alpha granule lumen relationship: transformation_of CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:B0066190 name: FIBA_HUMAN-Phosphothreonine412 def: "Protein FIBA_HUMAN with the residue 412 substituted with Phosphothreonine" [UniProtKB:P02671] xref: UniProtKB:P02671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:B0066191 name: FIBA_HUMAN-Phosphoserine524 def: "Protein FIBA_HUMAN with the residue 524 substituted with Phosphoserine" [UniProtKB:P02671] xref: UniProtKB:P02671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:B0066192 name: FIBA_HUMAN-Phosphoserine549 def: "Protein FIBA_HUMAN with the residue 549 substituted with Phosphoserine" [UniProtKB:P02671] xref: UniProtKB:P02671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:B0066193 name: FIBA_HUMAN-Phosphoserine609 def: "Protein FIBA_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:P02671] xref: UniProtKB:P02671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:B0066194 name: FIBB_HUMAN-Pyrrolidone carboxylic acid31 def: "Protein FIBB_HUMAN with the residue 31 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P02675] xref: UniProtKB:P02675 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054866 ! FIBB_HUMAN [Term] id: CCO:B0066195 name: FIBG_HUMAN-Sulfotyrosine444 def: "Protein FIBG_HUMAN with the residue 444 substituted with Sulfotyrosine" [UniProtKB:P02679] xref: UniProtKB:P02679 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054867 ! FIBG_HUMAN [Term] id: CCO:B0066196 name: FIBG_HUMAN-Sulfotyrosine448 def: "Protein FIBG_HUMAN with the residue 448 substituted with Sulfotyrosine" [UniProtKB:P02679] xref: UniProtKB:P02679 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054867 ! FIBG_HUMAN [Term] id: CCO:B0066197 name: FIZ1_HUMAN-Phosphothreonine74 def: "Protein FIZ1_HUMAN with the residue 74 substituted with Phosphothreonine" [UniProtKB:Q96SL8] xref: UniProtKB:Q96SL8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058392 ! FIZ1_HUMAN [Term] id: CCO:B0066198 name: FKBP5_HUMAN-Phosphoserine13 def: "Protein FKBP5_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:Q13451] xref: UniProtKB:Q13451 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001658 ! FK506 binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063039 ! FKBP5_HUMAN [Term] id: CCO:B0066199 name: FKBP5_HUMAN-Phosphoserine445 def: "Protein FKBP5_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:Q13451] xref: UniProtKB:Q13451 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063039 ! FKBP5_HUMAN [Term] id: CCO:B0066200 name: FKBP8_HUMAN-Phosphotyrosine322 def: "Protein FKBP8_HUMAN with the residue 322 substituted with Phosphotyrosine" [UniProtKB:Q14318] xref: UniProtKB:Q14318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055978 ! FKBP8_HUMAN [Term] id: CCO:B0066201 name: FLCN_HUMAN-Phosphoserine62 def: "Protein FLCN_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q8NFG4] xref: UniProtKB:Q8NFG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001981 ! FLCN_HUMAN [Term] id: CCO:B0066202 name: FLCN_HUMAN-Phosphoserine73 def: "Protein FLCN_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:Q8NFG4] xref: UniProtKB:Q8NFG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001981 ! FLCN_HUMAN [Term] id: CCO:B0066203 name: FLI1_HUMAN-Phosphoserine76 def: "Protein FLI1_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q01543] xref: UniProtKB:Q01543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055690 ! FLI1_HUMAN [Term] id: CCO:B0066204 name: FLI1_HUMAN-Phosphoserine86 def: "Protein FLI1_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q01543] xref: UniProtKB:Q01543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055690 ! FLI1_HUMAN [Term] id: CCO:B0066205 name: FLI1_HUMAN-Phosphoserine89 def: "Protein FLI1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q01543] xref: UniProtKB:Q01543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055690 ! FLI1_HUMAN [Term] id: CCO:B0066206 name: FLII_HUMAN-N-acetylmethionine1 def: "Protein FLII_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q13045] xref: UniProtKB:Q13045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055869 ! FLII_HUMAN [Term] id: CCO:B0066207 name: FLII_HUMAN-Phosphoserine406 def: "Protein FLII_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:Q13045] xref: UniProtKB:Q13045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055869 ! FLII_HUMAN [Term] id: CCO:B0066208 name: FLII_HUMAN-Phosphoserine436 def: "Protein FLII_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q13045] comment: By similarity xref: UniProtKB:Q13045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055869 ! FLII_HUMAN [Term] id: CCO:B0066209 name: FLII_HUMAN-Phosphoserine856 def: "Protein FLII_HUMAN with the residue 856 substituted with Phosphoserine" [UniProtKB:Q13045] xref: UniProtKB:Q13045 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055869 ! FLII_HUMAN [Term] id: CCO:B0066210 name: FLNA_HUMAN-Phosphotyrosine373 def: "Protein FLNA_HUMAN with the residue 373 substituted with Phosphotyrosine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0066211 name: FLNA_HUMAN-Phosphotyrosine1604 def: "Protein FLNA_HUMAN with the residue 1604 substituted with Phosphotyrosine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0066212 name: FLNA_HUMAN-Phosphotyrosine2388 def: "Protein FLNA_HUMAN with the residue 2388 substituted with Phosphotyrosine" [UniProtKB:P21333] xref: UniProtKB:P21333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:B0066213 name: FLNC_HUMAN-Phosphotyrosine2683 def: "Protein FLNC_HUMAN with the residue 2683 substituted with Phosphotyrosine" [UniProtKB:Q14315] xref: UniProtKB:Q14315 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0041399 ! FLNC_HUMAN [Term] id: CCO:B0066214 name: FLOT1_HUMAN-Phosphotyrosine203 def: "Protein FLOT1_HUMAN with the residue 203 substituted with Phosphotyrosine" [UniProtKB:O75955] xref: UniProtKB:O75955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000385 ! microtubule organizing center relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000815 ! flotillin complex relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0002123 ! membrane raft relationship: located_in CCO:C0002178 ! centriolar satellite relationship: transformation_of CCO:B0062976 ! FLOT1_HUMAN [Term] id: CCO:B0066215 name: FLOT2_HUMAN-Phosphotyrosine192 def: "Protein FLOT2_HUMAN with the residue 192 substituted with Phosphotyrosine" [UniProtKB:Q14254] comment: By similarity xref: UniProtKB:Q14254 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000815 ! flotillin complex relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0062977 ! FLOT2_HUMAN [Term] id: CCO:B0066216 name: FMNL2_HUMAN-Phosphoserine171 def: "Protein FMNL2_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q96PY5] xref: UniProtKB:Q96PY5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058348 ! FMNL2_HUMAN [Term] id: CCO:B0066217 name: FMNL2_HUMAN-Phosphoserine1017 def: "Protein FMNL2_HUMAN with the residue 1017 substituted with Phosphoserine" [UniProtKB:Q96PY5] xref: UniProtKB:Q96PY5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058348 ! FMNL2_HUMAN [Term] id: CCO:B0066218 name: FMNL_HUMAN-Phosphoserine184 def: "Protein FMNL_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:O95466] xref: UniProtKB:O95466 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0003531 ! Rho GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063463 ! FMNL_HUMAN [Term] id: CCO:B0066219 name: FMNL_HUMAN-Phosphoserine624 def: "Protein FMNL_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:O95466] xref: UniProtKB:O95466 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063463 ! FMNL_HUMAN [Term] id: CCO:B0066220 name: FMOD_HUMAN-Pyrrolidone carboxylic acid19 def: "Protein FMOD_HUMAN with the residue 19 substituted with Pyrrolidone carboxylic acid" [UniProtKB:Q06828] xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066221 name: FMOD_HUMAN-Sulfotyrosine20 def: "Protein FMOD_HUMAN with the residue 20 substituted with Sulfotyrosine" [UniProtKB:Q06828] xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066222 name: FMOD_HUMAN-Sulfotyrosine38 def: "Protein FMOD_HUMAN with the residue 38 substituted with Sulfotyrosine" [UniProtKB:Q06828] comment: Probable xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066223 name: FMOD_HUMAN-Sulfotyrosine39 def: "Protein FMOD_HUMAN with the residue 39 substituted with Sulfotyrosine" [UniProtKB:Q06828] comment: Probable xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066224 name: FMOD_HUMAN-Sulfotyrosine45 def: "Protein FMOD_HUMAN with the residue 45 substituted with Sulfotyrosine" [UniProtKB:Q06828] comment: Probable xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066225 name: FMOD_HUMAN-Sulfotyrosine47 def: "Protein FMOD_HUMAN with the residue 47 substituted with Sulfotyrosine" [UniProtKB:Q06828] comment: Probable xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066226 name: FMOD_HUMAN-Sulfotyrosine53 def: "Protein FMOD_HUMAN with the residue 53 substituted with Sulfotyrosine" [UniProtKB:Q06828] xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066227 name: FMOD_HUMAN-Sulfotyrosine55 def: "Protein FMOD_HUMAN with the residue 55 substituted with Sulfotyrosine" [UniProtKB:Q06828] xref: UniProtKB:Q06828 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: transformation_of CCO:B0055774 ! FMOD_HUMAN [Term] id: CCO:B0066228 name: FN3K_HUMAN-N-acetylmethionine1 def: "Protein FN3K_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q9H479] xref: UniProtKB:Q9H479 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063226 ! FN3K_HUMAN [Term] id: CCO:B0066229 name: FN3K_HUMAN-Phosphoserine258 def: "Protein FN3K_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q9H479] xref: UniProtKB:Q9H479 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004426 ! fructosamine-3-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0063226 ! FN3K_HUMAN [Term] id: CCO:B0066230 name: FN3K_HUMAN-Phosphotyrosine263 def: "Protein FN3K_HUMAN with the residue 263 substituted with Phosphotyrosine" [UniProtKB:Q9H479] xref: UniProtKB:Q9H479 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063226 ! FN3K_HUMAN [Term] id: CCO:B0066231 name: FNBP1_HUMAN-Phosphoserine349 def: "Protein FNBP1_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q96RU3] xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0066232 name: FNBP1_HUMAN-Phosphoserine359 def: "Protein FNBP1_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:Q96RU3] xref: UniProtKB:Q96RU3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:B0066233 name: FNBP2_HUMAN-Phosphoserine799 def: "Protein FNBP2_HUMAN with the residue 799 substituted with Phosphoserine" [UniProtKB:O75044] comment: By similarity xref: UniProtKB:O75044 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054598 ! FNBP2_HUMAN [Term] id: CCO:B0066234 name: FNTA_HUMAN-Phosphoserine373 def: "Protein FNTA_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:P49354] xref: UniProtKB:P49354 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055421 ! FNTA_HUMAN [Term] id: CCO:B0066235 name: FNTB_HUMAN-Phosphotyrosine300 def: "Protein FNTB_HUMAN with the residue 300 substituted with Phosphotyrosine" [UniProtKB:P49356] xref: UniProtKB:P49356 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:B0066236 name: FOG1_HUMAN-Phosphoserine489 def: "Protein FOG1_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q8IX07] comment: By similarity xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066237 name: FOG1_HUMAN-Phosphoserine492 def: "Protein FOG1_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q8IX07] comment: By similarity xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066238 name: FOG1_HUMAN-Phosphoserine636 def: "Protein FOG1_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:Q8IX07] comment: By similarity xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066239 name: FOG1_HUMAN-Phosphothreonine651 def: "Protein FOG1_HUMAN with the residue 651 substituted with Phosphothreonine" [UniProtKB:Q8IX07] comment: By similarity xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066240 name: FOG1_HUMAN-Phosphoserine664 def: "Protein FOG1_HUMAN with the residue 664 substituted with Phosphoserine" [UniProtKB:Q8IX07] xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066241 name: FOG1_HUMAN-Phosphoserine666 def: "Protein FOG1_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:Q8IX07] xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066242 name: FOG1_HUMAN-Phosphotyrosine696 def: "Protein FOG1_HUMAN with the residue 696 substituted with Phosphotyrosine" [UniProtKB:Q8IX07] xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066243 name: FOG1_HUMAN-Phosphothreonine697 def: "Protein FOG1_HUMAN with the residue 697 substituted with Phosphothreonine" [UniProtKB:Q8IX07] xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066244 name: FOG1_HUMAN-Phosphoserine784 def: "Protein FOG1_HUMAN with the residue 784 substituted with Phosphoserine" [UniProtKB:Q8IX07] xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066245 name: FOG1_HUMAN-Phosphoserine933 def: "Protein FOG1_HUMAN with the residue 933 substituted with Phosphoserine" [UniProtKB:Q8IX07] comment: By similarity xref: UniProtKB:Q8IX07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057367 ! FOG1_HUMAN [Term] id: CCO:B0066246 name: FOSL2_HUMAN-Phosphoserine83 def: "Protein FOSL2_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P15408] xref: UniProtKB:P15408 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055036 ! FOSL2_HUMAN [Term] id: CCO:B0066247 name: FOSL2_HUMAN-Phosphoserine120 def: "Protein FOSL2_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P15408] xref: UniProtKB:P15408 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055036 ! FOSL2_HUMAN [Term] id: CCO:B0066248 name: FOSL2_HUMAN-Phosphoserine200 def: "Protein FOSL2_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:P15408] xref: UniProtKB:P15408 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055036 ! FOSL2_HUMAN [Term] id: CCO:B0066249 name: FOSL2_HUMAN-Phosphoserine230 def: "Protein FOSL2_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:P15408] xref: UniProtKB:P15408 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055036 ! FOSL2_HUMAN [Term] id: CCO:B0066250 name: FOSL2_HUMAN-Phosphoserine308 def: "Protein FOSL2_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:P15408] xref: UniProtKB:P15408 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055036 ! FOSL2_HUMAN [Term] id: CCO:B0066251 name: FOSL2_HUMAN-Phosphoserine320 def: "Protein FOSL2_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:P15408] xref: UniProtKB:P15408 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055036 ! FOSL2_HUMAN [Term] id: CCO:B0066252 name: FOXC1_HUMAN-Phosphoserine235 def: "Protein FOXC1_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q12948] xref: UniProtKB:Q12948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000310 ! nuclear heterochromatin relationship: transformation_of CCO:B0001735 ! FOXC1_HUMAN [Term] id: CCO:B0066253 name: FOXC1_HUMAN-Phosphoserine241 def: "Protein FOXC1_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:Q12948] xref: UniProtKB:Q12948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001735 ! FOXC1_HUMAN [Term] id: CCO:B0066254 name: FOXC2_HUMAN-Phosphoserine36 def: "Protein FOXC2_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0066255 name: FOXC2_HUMAN-Phosphoserine215 def: "Protein FOXC2_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0066256 name: FOXC2_HUMAN-Phosphoserine288 def: "Protein FOXC2_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q99958] xref: UniProtKB:Q99958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016732 ! FOXC2_HUMAN [Term] id: CCO:B0066257 name: FOXJ2_HUMAN-Phosphotyrosine259 def: "Protein FOXJ2_HUMAN with the residue 259 substituted with Phosphotyrosine" [UniProtKB:Q9P0K8] xref: UniProtKB:Q9P0K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039140 ! FOXJ2_HUMAN [Term] id: CCO:B0066258 name: FOXJ2_HUMAN-Phosphoserine261 def: "Protein FOXJ2_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:Q9P0K8] xref: UniProtKB:Q9P0K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039140 ! FOXJ2_HUMAN [Term] id: CCO:B0066259 name: FOXJ3_HUMAN-Phosphoserine223 def: "Protein FOXJ3_HUMAN with the residue 223 substituted with Phosphoserine" [UniProtKB:Q9UPW0] xref: UniProtKB:Q9UPW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0039141 ! FOXJ3_HUMAN [Term] id: CCO:B0066260 name: FOXK1_HUMAN-Phosphoserine101 def: "Protein FOXK1_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0066261 name: FOXK1_HUMAN-Phosphoserine239 def: "Protein FOXK1_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0066262 name: FOXK1_HUMAN-Phosphoserine243 def: "Protein FOXK1_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0066263 name: FOXK1_HUMAN-Phosphoserine253 def: "Protein FOXK1_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0066264 name: FOXK1_HUMAN-Phosphoserine257 def: "Protein FOXK1_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0066265 name: FOXK1_HUMAN-Phosphoserine455 def: "Protein FOXK1_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:P85037] xref: UniProtKB:P85037 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015239 ! FOXK1_HUMAN [Term] id: CCO:B0066266 name: FOXM1_HUMAN-Phosphoserine331 def: "Protein FOXM1_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q08050] xref: UniProtKB:Q08050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055788 ! FOXM1_HUMAN [Term] id: CCO:B0066267 name: FOXM1_HUMAN-Phosphothreonine620 def: "Protein FOXM1_HUMAN with the residue 620 substituted with Phosphothreonine" [UniProtKB:Q08050] xref: UniProtKB:Q08050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055788 ! FOXM1_HUMAN [Term] id: CCO:B0066268 name: FOXM1_HUMAN-Phosphothreonine627 def: "Protein FOXM1_HUMAN with the residue 627 substituted with Phosphothreonine" [UniProtKB:Q08050] xref: UniProtKB:Q08050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055788 ! FOXM1_HUMAN [Term] id: CCO:B0066269 name: FOXM1_HUMAN-Phosphothreonine662 def: "Protein FOXM1_HUMAN with the residue 662 substituted with Phosphothreonine" [UniProtKB:Q08050] comment: Probable xref: UniProtKB:Q08050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055788 ! FOXM1_HUMAN [Term] id: CCO:B0066270 name: FOXM1_HUMAN-Phosphoserine704 def: "Protein FOXM1_HUMAN with the residue 704 substituted with Phosphoserine" [UniProtKB:Q08050] xref: UniProtKB:Q08050 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055788 ! FOXM1_HUMAN [Term] id: CCO:B0066271 name: FOXO1_HUMAN-Phosphoserine287 def: "Protein FOXO1_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q12778] xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0066272 name: FOXO1_HUMAN-Phosphoserine322 def: "Protein FOXO1_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:Q12778] comment: by CK1; xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0066273 name: FOXO1_HUMAN-Phosphoserine325 def: "Protein FOXO1_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:Q12778] comment: by CK1; xref: UniProtKB:Q12778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:B0066274 name: FOXP1_HUMAN-Phosphoserine440 def: "Protein FOXP1_HUMAN with the residue 440 substituted with Phosphoserine" [UniProtKB:Q9H334] xref: UniProtKB:Q9H334 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015712 ! FOXP1_HUMAN [Term] id: CCO:B0066275 name: FR1OP_HUMAN-Phosphoserine156 def: "Protein FR1OP_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:O95684] xref: UniProtKB:O95684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054783 ! FR1OP_HUMAN [Term] id: CCO:B0066276 name: FR1OP_HUMAN-Phosphoserine160 def: "Protein FR1OP_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:O95684] xref: UniProtKB:O95684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054783 ! FR1OP_HUMAN [Term] id: CCO:B0066277 name: FR1OP_HUMAN-Phosphotyrosine337 def: "Protein FR1OP_HUMAN with the residue 337 substituted with Phosphotyrosine" [UniProtKB:O95684] comment: By similarity xref: UniProtKB:O95684 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0054783 ! FR1OP_HUMAN [Term] id: CCO:B0066278 name: FRIH_HUMAN-Phosphoserine183 def: "Protein FRIH_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:P02794] xref: UniProtKB:P02794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033704 ! FRIH_HUMAN [Term] id: CCO:B0066279 name: FRK_HUMAN-Phosphotyrosine46 def: "Protein FRK_HUMAN with the residue 46 substituted with Phosphotyrosine" [UniProtKB:P42685] xref: UniProtKB:P42685 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001613 ! FRK_HUMAN [Term] id: CCO:B0066280 name: FRMD6_HUMAN-Phosphoserine544 def: "Protein FRMD6_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:Q96NE9] xref: UniProtKB:Q96NE9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005267 ! FRMD6_HUMAN [Term] id: CCO:B0066281 name: FRS2_HUMAN-Phosphothreonine288 def: "Protein FRS2_HUMAN with the residue 288 substituted with Phosphothreonine" [UniProtKB:Q8WU20] comment: By similarity xref: UniProtKB:Q8WU20 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001378 ! transmembrane receptor protein tyrosine kinase adaptor protein activity relationship: has_function CCO:F0001379 ! transmembrane receptor protein tyrosine kinase docking protein activity relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003112 ! regulator of G-protein signaling activity relationship: has_function CCO:F0004134 ! phosphatase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057975 ! FRS2_HUMAN [Term] id: CCO:B0066282 name: FRYL_HUMAN-Phosphoserine2272 def: "Protein FRYL_HUMAN with the residue 2272 substituted with Phosphoserine" [UniProtKB:O94915] xref: UniProtKB:O94915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054711 ! FRYL_HUMAN [Term] id: CCO:B0066283 name: FRY_HUMAN-Phosphothreonine951 def: "Protein FRY_HUMAN with the residue 951 substituted with Phosphothreonine" [UniProtKB:Q5TBA9] xref: UniProtKB:Q5TBA9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056605 ! FRY_HUMAN [Term] id: CCO:B0066284 name: FRY_HUMAN-Phosphotyrosine954 def: "Protein FRY_HUMAN with the residue 954 substituted with Phosphotyrosine" [UniProtKB:Q5TBA9] xref: UniProtKB:Q5TBA9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056605 ! FRY_HUMAN [Term] id: CCO:B0066285 name: FSCN1_HUMAN-N-acetylthreonine2 def: "Protein FSCN1_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:Q16658] comment: Probable xref: UniProtKB:Q16658 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056170 ! FSCN1_HUMAN [Term] id: CCO:B0066286 name: FSCN1_HUMAN-Phosphoserine38 def: "Protein FSCN1_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:Q16658] xref: UniProtKB:Q16658 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056170 ! FSCN1_HUMAN [Term] id: CCO:B0066287 name: FSCN1_HUMAN-Phosphoserine39 def: "Protein FSCN1_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q16658] comment: by PKC; xref: UniProtKB:Q16658 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000989 ! filopodium relationship: transformation_of CCO:B0056170 ! FSCN1_HUMAN [Term] id: CCO:B0066288 name: FUBP1_HUMAN-Phosphotyrosine58 def: "Protein FUBP1_HUMAN with the residue 58 substituted with Phosphotyrosine" [UniProtKB:Q96AE4] xref: UniProtKB:Q96AE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:B0066289 name: FUBP1_HUMAN-Phosphoserine140 def: "Protein FUBP1_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q96AE4] xref: UniProtKB:Q96AE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:B0066290 name: FUBP1_HUMAN-Phosphothreonine153 def: "Protein FUBP1_HUMAN with the residue 153 substituted with Phosphothreonine" [UniProtKB:Q96AE4] xref: UniProtKB:Q96AE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:B0066291 name: FUBP1_HUMAN-Phosphoserine630 def: "Protein FUBP1_HUMAN with the residue 630 substituted with Phosphoserine" [UniProtKB:Q96AE4] xref: UniProtKB:Q96AE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:B0066292 name: FUBP2_HUMAN-Phosphothreonine100 def: "Protein FUBP2_HUMAN with the residue 100 substituted with Phosphothreonine" [UniProtKB:Q92945] xref: UniProtKB:Q92945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058114 ! FUBP2_HUMAN [Term] id: CCO:B0066293 name: FUBP2_HUMAN-Phosphoserine132 def: "Protein FUBP2_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q92945] xref: UniProtKB:Q92945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058114 ! FUBP2_HUMAN [Term] id: CCO:B0066294 name: FUBP2_HUMAN-Phosphoserine181 def: "Protein FUBP2_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q92945] xref: UniProtKB:Q92945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058114 ! FUBP2_HUMAN [Term] id: CCO:B0066295 name: FUBP2_HUMAN-Phosphoserine274 def: "Protein FUBP2_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q92945] xref: UniProtKB:Q92945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058114 ! FUBP2_HUMAN [Term] id: CCO:B0066296 name: FUBP2_HUMAN-Phosphoserine480 def: "Protein FUBP2_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:Q92945] xref: UniProtKB:Q92945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058114 ! FUBP2_HUMAN [Term] id: CCO:B0066297 name: FUBP2_HUMAN-Phosphoserine670 def: "Protein FUBP2_HUMAN with the residue 670 substituted with Phosphoserine" [UniProtKB:Q92945] xref: UniProtKB:Q92945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058114 ! FUBP2_HUMAN [Term] id: CCO:B0066298 name: FUBP3_HUMAN-N-acetylalanine2 def: "Protein FUBP3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q96I24] xref: UniProtKB:Q96I24 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058224 ! FUBP3_HUMAN [Term] id: CCO:B0066299 name: FUBP3_HUMAN-Phosphoserine296 def: "Protein FUBP3_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q96I24] xref: UniProtKB:Q96I24 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058224 ! FUBP3_HUMAN [Term] id: CCO:B0066300 name: FUBP3_HUMAN-Phosphoserine569 def: "Protein FUBP3_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q96I24] xref: UniProtKB:Q96I24 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058224 ! FUBP3_HUMAN [Term] id: CCO:B0066301 name: FUMH_HUMAN-Phosphotyrosine491 def: "Protein FUMH_HUMAN with the residue 491 substituted with Phosphotyrosine" [UniProtKB:P07954] xref: UniProtKB:P07954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000752 ! fumarate hydratase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0001903 ! tricarboxylic acid cycle enzyme complex relationship: transformation_of CCO:B0001496 ! FUMH_HUMAN [Term] id: CCO:B0066302 name: FUND2_HUMAN-Phosphoserine151 def: "Protein FUND2_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q9BWH2] xref: UniProtKB:Q9BWH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0063393 ! FUND2_HUMAN [Term] id: CCO:B0066303 name: FURIN_HUMAN-Phosphoserine773 def: "Protein FURIN_HUMAN with the residue 773 substituted with Phosphoserine" [UniProtKB:P09958] comment: by CK2; xref: UniProtKB:P09958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000256 ! protease binding relationship: has_function CCO:F0000644 ! endopeptidase activity relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0000706 ! furin activity relationship: has_function CCO:F0000715 ! subtilase activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003378 ! proprotein convertase activity relationship: has_function CCO:F0005639 ! peptide binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007336 ! nerve growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: transformation_of CCO:B0023793 ! FURIN_HUMAN [Term] id: CCO:B0066304 name: FURIN_HUMAN-Phosphoserine775 def: "Protein FURIN_HUMAN with the residue 775 substituted with Phosphoserine" [UniProtKB:P09958] comment: by CK2; xref: UniProtKB:P09958 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023793 ! FURIN_HUMAN [Term] id: CCO:B0066305 name: FUSIP_HUMAN-Phosphotyrosine110 def: "Protein FUSIP_HUMAN with the residue 110 substituted with Phosphotyrosine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066306 name: FUSIP_HUMAN-Phosphoserine129 def: "Protein FUSIP_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066307 name: FUSIP_HUMAN-Phosphoserine131 def: "Protein FUSIP_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066308 name: FUSIP_HUMAN-Phosphoserine133 def: "Protein FUSIP_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066309 name: FUSIP_HUMAN-Phosphoserine156 def: "Protein FUSIP_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066310 name: FUSIP_HUMAN-Phosphoserine158 def: "Protein FUSIP_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066311 name: FUSIP_HUMAN-Phosphoserine160 def: "Protein FUSIP_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066312 name: FUSIP_HUMAN-Phosphoserine235 def: "Protein FUSIP_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066313 name: FUSIP_HUMAN-Phosphoserine251 def: "Protein FUSIP_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066314 name: FUSIP_HUMAN-Phosphoserine253 def: "Protein FUSIP_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066315 name: FUSIP_HUMAN-Phosphothreonine255 def: "Protein FUSIP_HUMAN with the residue 255 substituted with Phosphothreonine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_function CCO:F0008001 ! RS domain binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066316 name: FUSIP_HUMAN-Phosphoserine256 def: "Protein FUSIP_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:O75494] xref: UniProtKB:O75494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:B0066317 name: FUS_HUMAN-Omega-N-methylated arginine216 def: "Protein FUS_HUMAN with the residue 216 substituted with Omega-N-methylated arginine" [UniProtKB:P35637] xref: UniProtKB:P35637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063414 ! FUS_HUMAN [Term] id: CCO:B0066318 name: FUS_HUMAN-Omega-N-methylated arginine218 def: "Protein FUS_HUMAN with the residue 218 substituted with Omega-N-methylated arginine" [UniProtKB:P35637] xref: UniProtKB:P35637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063414 ! FUS_HUMAN [Term] id: CCO:B0066319 name: FYB_HUMAN-Phosphoserine28 def: "Protein FYB_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:O15117] comment: By similarity xref: UniProtKB:O15117 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054407 ! FYB_HUMAN [Term] id: CCO:B0066320 name: FYB_HUMAN-Phosphoserine46 def: "Protein FYB_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:O15117] xref: UniProtKB:O15117 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054407 ! FYB_HUMAN [Term] id: CCO:B0066321 name: FYB_HUMAN-Phosphothreonine158 def: "Protein FYB_HUMAN with the residue 158 substituted with Phosphothreonine" [UniProtKB:O15117] xref: UniProtKB:O15117 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054407 ! FYB_HUMAN [Term] id: CCO:B0066322 name: FYB_HUMAN-Phosphotyrosine571 def: "Protein FYB_HUMAN with the residue 571 substituted with Phosphotyrosine" [UniProtKB:O15117] xref: UniProtKB:O15117 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054407 ! FYB_HUMAN [Term] id: CCO:B0066323 name: FYB_HUMAN-Phosphoserine573 def: "Protein FYB_HUMAN with the residue 573 substituted with Phosphoserine" [UniProtKB:O15117] xref: UniProtKB:O15117 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054407 ! FYB_HUMAN [Term] id: CCO:B0066324 name: FYN_HUMAN-Phosphotyrosine213 def: "Protein FYN_HUMAN with the residue 213 substituted with Phosphotyrosine" [UniProtKB:P06241] xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0066325 name: FYN_HUMAN-Phosphotyrosine214 def: "Protein FYN_HUMAN with the residue 214 substituted with Phosphotyrosine" [UniProtKB:P06241] xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0066326 name: FYN_HUMAN-Phosphotyrosine440 def: "Protein FYN_HUMAN with the residue 440 substituted with Phosphotyrosine" [UniProtKB:P06241] xref: UniProtKB:P06241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:B0066327 name: FYV1_HUMAN-Phosphotyrosine46 def: "Protein FYV1_HUMAN with the residue 46 substituted with Phosphotyrosine" [UniProtKB:Q9Y2I7] xref: UniProtKB:Q9Y2I7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059307 ! FYV1_HUMAN [Term] id: CCO:B0066328 name: FYV1_HUMAN-Phosphoserine307 def: "Protein FYV1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q9Y2I7] comment: By similarity xref: UniProtKB:Q9Y2I7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059307 ! FYV1_HUMAN [Term] id: CCO:B0066329 name: FYV1_HUMAN-Phosphoserine318 def: "Protein FYV1_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q9Y2I7] xref: UniProtKB:Q9Y2I7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059307 ! FYV1_HUMAN [Term] id: CCO:B0066330 name: FYV1_HUMAN-Phosphoserine329 def: "Protein FYV1_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q9Y2I7] xref: UniProtKB:Q9Y2I7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059307 ! FYV1_HUMAN [Term] id: CCO:B0066331 name: FYV1_HUMAN-Phosphotyrosine1155 def: "Protein FYV1_HUMAN with the residue 1155 substituted with Phosphotyrosine" [UniProtKB:Q9Y2I7] xref: UniProtKB:Q9Y2I7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059307 ! FYV1_HUMAN [Term] id: CCO:B0066332 name: FYV1_HUMAN-Phosphotyrosine1772 def: "Protein FYV1_HUMAN with the residue 1772 substituted with Phosphotyrosine" [UniProtKB:Q9Y2I7] xref: UniProtKB:Q9Y2I7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003116 ! phosphatidylinositol phosphate kinase activity relationship: has_function CCO:F0003117 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0059307 ! FYV1_HUMAN [Term] id: CCO:B0066333 name: FZR_HUMAN-Phosphothreonine32 def: "Protein FZR_HUMAN with the residue 32 substituted with Phosphothreonine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0066334 name: FZR_HUMAN-Phosphoserine40 def: "Protein FZR_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0066335 name: FZR_HUMAN-Phosphoserine137 def: "Protein FZR_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0066336 name: FZR_HUMAN-Phosphoserine138 def: "Protein FZR_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0066337 name: FZR_HUMAN-Phosphoserine146 def: "Protein FZR_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q9UM11] xref: UniProtKB:Q9UM11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002229 ! FZR_HUMAN [Term] id: CCO:B0066338 name: G3BP1_HUMAN-Phosphothreonine143 def: "Protein G3BP1_HUMAN with the residue 143 substituted with Phosphothreonine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0066339 name: G3BP1_HUMAN-Phosphoserine373 def: "Protein G3BP1_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:Q13283] xref: UniProtKB:Q13283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028328 ! G3BP1_HUMAN [Term] id: CCO:B0066340 name: G3BP2_HUMAN-Phosphoserine235 def: "Protein G3BP2_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q9UN86] xref: UniProtKB:Q9UN86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028327 ! G3BP2_HUMAN [Term] id: CCO:B0066341 name: G3PT_HUMAN-Phosphothreonine318 def: "Protein G3PT_HUMAN with the residue 318 substituted with Phosphothreonine" [UniProtKB:O14556] comment: By similarity xref: UniProtKB:O14556 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054351 ! G3PT_HUMAN [Term] id: CCO:B0066342 name: GA2L1_HUMAN-Phosphothreonine193 def: "Protein GA2L1_HUMAN with the residue 193 substituted with Phosphothreonine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066343 name: GA2L1_HUMAN-Phosphoserine297 def: "Protein GA2L1_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066344 name: GA2L1_HUMAN-Phosphothreonine391 def: "Protein GA2L1_HUMAN with the residue 391 substituted with Phosphothreonine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066345 name: GA2L1_HUMAN-Phosphoserine394 def: "Protein GA2L1_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066346 name: GA2L1_HUMAN-Phosphoserine436 def: "Protein GA2L1_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066347 name: GA2L1_HUMAN-Phosphoserine438 def: "Protein GA2L1_HUMAN with the residue 438 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066348 name: GA2L1_HUMAN-Phosphoserine489 def: "Protein GA2L1_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066349 name: GA2L1_HUMAN-Phosphoserine490 def: "Protein GA2L1_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066350 name: GA2L1_HUMAN-Phosphoserine492 def: "Protein GA2L1_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066351 name: GA2L1_HUMAN-Phosphothreonine498 def: "Protein GA2L1_HUMAN with the residue 498 substituted with Phosphothreonine" [UniProtKB:Q99501] xref: UniProtKB:Q99501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002067 ! GA2L1_HUMAN [Term] id: CCO:B0066352 name: GA2L3_HUMAN-Phosphoserine438 def: "Protein GA2L3_HUMAN with the residue 438 substituted with Phosphoserine" [UniProtKB:Q86XJ1] xref: UniProtKB:Q86XJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001944 ! GA2L3_HUMAN [Term] id: CCO:B0066353 name: GA2L3_HUMAN-Phosphothreonine441 def: "Protein GA2L3_HUMAN with the residue 441 substituted with Phosphothreonine" [UniProtKB:Q86XJ1] xref: UniProtKB:Q86XJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001944 ! GA2L3_HUMAN [Term] id: CCO:B0066354 name: GA2L3_HUMAN-Phosphoserine570 def: "Protein GA2L3_HUMAN with the residue 570 substituted with Phosphoserine" [UniProtKB:Q86XJ1] xref: UniProtKB:Q86XJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001944 ! GA2L3_HUMAN [Term] id: CCO:B0066355 name: GAB1_HUMAN-Phosphotyrosine259 def: "Protein GAB1_HUMAN with the residue 259 substituted with Phosphotyrosine" [UniProtKB:Q13480] xref: UniProtKB:Q13480 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:B0066356 name: GAB1_HUMAN-Phosphoserine266 def: "Protein GAB1_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q13480] xref: UniProtKB:Q13480 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:B0066357 name: GAB1_HUMAN-Phosphotyrosine406 def: "Protein GAB1_HUMAN with the residue 406 substituted with Phosphotyrosine" [UniProtKB:Q13480] xref: UniProtKB:Q13480 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:B0066358 name: GAB1_HUMAN-Phosphothreonine503 def: "Protein GAB1_HUMAN with the residue 503 substituted with Phosphothreonine" [UniProtKB:Q13480] comment: By similarity xref: UniProtKB:Q13480 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:B0066359 name: GAB1_HUMAN-Phosphotyrosine627 def: "Protein GAB1_HUMAN with the residue 627 substituted with Phosphotyrosine" [UniProtKB:Q13480] xref: UniProtKB:Q13480 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:B0066360 name: GAB1_HUMAN-Phosphotyrosine659 def: "Protein GAB1_HUMAN with the residue 659 substituted with Phosphotyrosine" [UniProtKB:Q13480] xref: UniProtKB:Q13480 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:B0066361 name: GAB2_HUMAN-Phosphoserine543 def: "Protein GAB2_HUMAN with the residue 543 substituted with Phosphoserine" [UniProtKB:Q9UQC2] xref: UniProtKB:Q9UQC2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005924 ! GAB2_HUMAN [Term] id: CCO:B0066362 name: GALA_HUMAN-Phosphoserine117 def: "Protein GALA_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:P22466] xref: UniProtKB:P22466 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000985 ! secretory granule relationship: transformation_of CCO:B0055148 ! GALA_HUMAN [Term] id: CCO:B0066363 name: GALR2_HUMAN-Phosphotyrosine213 def: "Protein GALR2_HUMAN with the residue 213 substituted with Phosphotyrosine" [UniProtKB:O43603] xref: UniProtKB:O43603 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054498 ! GALR2_HUMAN [Term] id: CCO:B0066364 name: GAN_HUMAN-Phosphotyrosine471 def: "Protein GAN_HUMAN with the residue 471 substituted with Phosphotyrosine" [UniProtKB:Q9H2C0] xref: UniProtKB:Q9H2C0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063005 ! GAN_HUMAN [Term] id: CCO:B0066365 name: GAPD1_HUMAN-Phosphothreonine390 def: "Protein GAPD1_HUMAN with the residue 390 substituted with Phosphothreonine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066366 name: GAPD1_HUMAN-Phosphothreonine458 def: "Protein GAPD1_HUMAN with the residue 458 substituted with Phosphothreonine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066367 name: GAPD1_HUMAN-Phosphoserine466 def: "Protein GAPD1_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066368 name: GAPD1_HUMAN-Phosphothreonine470 def: "Protein GAPD1_HUMAN with the residue 470 substituted with Phosphothreonine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066369 name: GAPD1_HUMAN-Phosphoserine566 def: "Protein GAPD1_HUMAN with the residue 566 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066370 name: GAPD1_HUMAN-Phosphoserine569 def: "Protein GAPD1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066371 name: GAPD1_HUMAN-Phosphoserine742 def: "Protein GAPD1_HUMAN with the residue 742 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066372 name: GAPD1_HUMAN-Phosphoserine746 def: "Protein GAPD1_HUMAN with the residue 746 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066373 name: GAPD1_HUMAN-Phosphothreonine747 def: "Protein GAPD1_HUMAN with the residue 747 substituted with Phosphothreonine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066374 name: GAPD1_HUMAN-Phosphoserine748 def: "Protein GAPD1_HUMAN with the residue 748 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066375 name: GAPD1_HUMAN-Phosphoserine902 def: "Protein GAPD1_HUMAN with the residue 902 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066376 name: GAPD1_HUMAN-Phosphoserine903 def: "Protein GAPD1_HUMAN with the residue 903 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066377 name: GAPD1_HUMAN-Phosphoserine966 def: "Protein GAPD1_HUMAN with the residue 966 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0005038 ! GTPase activating protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066378 name: GAPD1_HUMAN-Phosphoserine1019 def: "Protein GAPD1_HUMAN with the residue 1019 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066379 name: GAPD1_HUMAN-Phosphoserine1096 def: "Protein GAPD1_HUMAN with the residue 1096 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066380 name: GAPD1_HUMAN-Phosphoserine1105 def: "Protein GAPD1_HUMAN with the residue 1105 substituted with Phosphoserine" [UniProtKB:Q14C86] xref: UniProtKB:Q14C86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056032 ! GAPD1_HUMAN [Term] id: CCO:B0066381 name: GARL3_HUMAN-Phosphothreonine827 def: "Protein GARL3_HUMAN with the residue 827 substituted with Phosphothreonine" [UniProtKB:Q5VVW2] xref: UniProtKB:Q5VVW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0056661 ! GARL3_HUMAN [Term] id: CCO:B0066382 name: GAS2_HUMAN-Phosphoserine282 def: "Protein GAS2_HUMAN with the residue 282 substituted with Phosphoserine" [UniProtKB:O43903] comment: By similarity xref: UniProtKB:O43903 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001401 ! GAS2_HUMAN [Term] id: CCO:B0066383 name: GAST_HUMAN-acid59 def: "Protein GAST_HUMAN with the residue 59 substituted with acid" [UniProtKB:P01350] comment: in form big gastrin; xref: UniProtKB:P01350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054854 ! GAST_HUMAN [Term] id: CCO:B0066384 name: GAST_HUMAN-acid76 def: "Protein GAST_HUMAN with the residue 76 substituted with acid" [UniProtKB:P01350] comment: in form gastrin; xref: UniProtKB:P01350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054854 ! GAST_HUMAN [Term] id: CCO:B0066385 name: GAST_HUMAN-Sulfotyrosine87 def: "Protein GAST_HUMAN with the residue 87 substituted with Sulfotyrosine" [UniProtKB:P01350] comment: partial; xref: UniProtKB:P01350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0054854 ! GAST_HUMAN [Term] id: CCO:B0066386 name: GAST_HUMAN-Phenylalanine amide92 def: "Protein GAST_HUMAN with the residue 92 substituted with Phenylalanine amide" [UniProtKB:P01350] xref: UniProtKB:P01350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054854 ! GAST_HUMAN [Term] id: CCO:B0066387 name: GAST_HUMAN-Phosphoserine96 def: "Protein GAST_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:P01350] comment: By similarity xref: UniProtKB:P01350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054854 ! GAST_HUMAN [Term] id: CCO:B0066388 name: GBB1_HUMAN-N-acetylserine2 def: "Protein GBB1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62873] xref: UniProtKB:P62873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055621 ! GBB1_HUMAN [Term] id: CCO:B0066389 name: GBB2_HUMAN-N-acetylserine2 def: "Protein GBB2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62879] xref: UniProtKB:P62879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055623 ! GBB2_HUMAN [Term] id: CCO:B0066390 name: GBB2_HUMAN-Phosphotyrosine239 def: "Protein GBB2_HUMAN with the residue 239 substituted with Phosphotyrosine" [UniProtKB:P62879] comment: By similarity xref: UniProtKB:P62879 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055623 ! GBB2_HUMAN [Term] id: CCO:B0066391 name: GBB3_HUMAN-Phosphoserine74 def: "Protein GBB3_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:P16520] comment: By similarity xref: UniProtKB:P16520 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055056 ! GBB3_HUMAN [Term] id: CCO:B0066392 name: GBB4_HUMAN-N-acetylserine2 def: "Protein GBB4_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9HAV0] xref: UniProtKB:Q9HAV0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058769 ! GBB4_HUMAN [Term] id: CCO:B0066393 name: GBF1_HUMAN-Phosphothreonine507 def: "Protein GBF1_HUMAN with the residue 507 substituted with Phosphothreonine" [UniProtKB:Q92538] xref: UniProtKB:Q92538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005359 ! GBF1_HUMAN [Term] id: CCO:B0066394 name: GBF1_HUMAN-Phosphoserine662 def: "Protein GBF1_HUMAN with the residue 662 substituted with Phosphoserine" [UniProtKB:Q92538] xref: UniProtKB:Q92538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005359 ! GBF1_HUMAN [Term] id: CCO:B0066395 name: GBF1_HUMAN-Phosphoserine1298 def: "Protein GBF1_HUMAN with the residue 1298 substituted with Phosphoserine" [UniProtKB:Q92538] xref: UniProtKB:Q92538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005359 ! GBF1_HUMAN [Term] id: CCO:B0066396 name: GBF1_HUMAN-Phosphoserine1318 def: "Protein GBF1_HUMAN with the residue 1318 substituted with Phosphoserine" [UniProtKB:Q92538] xref: UniProtKB:Q92538 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005359 ! GBF1_HUMAN [Term] id: CCO:B0066397 name: GBG12_HUMAN-N-acetylserine2 def: "Protein GBG12_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9UBI6] comment: By similarity xref: UniProtKB:Q9UBI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059075 ! GBG12_HUMAN [Term] id: CCO:B0066398 name: GBG12_HUMAN-Phosphoserine26 def: "Protein GBG12_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q9UBI6] xref: UniProtKB:Q9UBI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059075 ! GBG12_HUMAN [Term] id: CCO:B0066399 name: GBG12_HUMAN-Phosphotyrosine42 def: "Protein GBG12_HUMAN with the residue 42 substituted with Phosphotyrosine" [UniProtKB:Q9UBI6] xref: UniProtKB:Q9UBI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059075 ! GBG12_HUMAN [Term] id: CCO:B0066400 name: GBG2_HUMAN-N-acetylalanine2 def: "Protein GBG2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P59768] comment: By similarity xref: UniProtKB:P59768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055589 ! GBG2_HUMAN [Term] id: CCO:B0066401 name: GBG2_HUMAN-Phosphothreonine52 def: "Protein GBG2_HUMAN with the residue 52 substituted with Phosphothreonine" [UniProtKB:P59768] comment: By similarity xref: UniProtKB:P59768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055589 ! GBG2_HUMAN [Term] id: CCO:B0066402 name: GBG3_HUMAN-Phosphothreonine5 def: "Protein GBG3_HUMAN with the residue 5 substituted with Phosphothreonine" [UniProtKB:P63215] comment: By similarity xref: UniProtKB:P63215 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055632 ! GBG3_HUMAN [Term] id: CCO:B0066403 name: GBG3_HUMAN-Phosphoserine9 def: "Protein GBG3_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P63215] comment: By similarity xref: UniProtKB:P63215 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055632 ! GBG3_HUMAN [Term] id: CCO:B0066404 name: GCFC_HUMAN-Phosphoserine16 def: "Protein GCFC_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066405 name: GCFC_HUMAN-Phosphoserine62 def: "Protein GCFC_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066406 name: GCFC_HUMAN-Phosphoserine154 def: "Protein GCFC_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066407 name: GCFC_HUMAN-Phosphoserine155 def: "Protein GCFC_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066408 name: GCFC_HUMAN-Phosphoserine158 def: "Protein GCFC_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066409 name: GCFC_HUMAN-Phosphoserine191 def: "Protein GCFC_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066410 name: GCFC_HUMAN-Phosphoserine262 def: "Protein GCFC_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066411 name: GCFC_HUMAN-Phosphothreonine378 def: "Protein GCFC_HUMAN with the residue 378 substituted with Phosphothreonine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066412 name: GCFC_HUMAN-Phosphoserine380 def: "Protein GCFC_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066413 name: GCFC_HUMAN-Phosphoserine557 def: "Protein GCFC_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066414 name: GCFC_HUMAN-Phosphoserine558 def: "Protein GCFC_HUMAN with the residue 558 substituted with Phosphoserine" [UniProtKB:Q9Y5B6] xref: UniProtKB:Q9Y5B6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059376 ! GCFC_HUMAN [Term] id: CCO:B0066415 name: GCF_HUMAN-Phosphoserine16 def: "Protein GCF_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066416 name: GCF_HUMAN-Phosphoserine17 def: "Protein GCF_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066417 name: GCF_HUMAN-Phosphoserine19 def: "Protein GCF_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066418 name: GCF_HUMAN-Phosphoserine96 def: "Protein GCF_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066419 name: GCF_HUMAN-Phosphothreonine97 def: "Protein GCF_HUMAN with the residue 97 substituted with Phosphothreonine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066420 name: GCF_HUMAN-Phosphoserine129 def: "Protein GCF_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:P16383] comment: By similarity xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066421 name: GCF_HUMAN-Phosphoserine180 def: "Protein GCF_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066422 name: GCF_HUMAN-Phosphoserine429 def: "Protein GCF_HUMAN with the residue 429 substituted with Phosphoserine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066423 name: GCF_HUMAN-Phosphoserine430 def: "Protein GCF_HUMAN with the residue 430 substituted with Phosphoserine" [UniProtKB:P16383] xref: UniProtKB:P16383 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055049 ! GCF_HUMAN [Term] id: CCO:B0066424 name: GCN1L_HUMAN-N-acetylalanine2 def: "Protein GCN1L_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q92616] xref: UniProtKB:Q92616 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000407 ! ribosome relationship: transformation_of CCO:B0058073 ! GCN1L_HUMAN [Term] id: CCO:B0066425 name: GCN1L_HUMAN-Phosphoserine95 def: "Protein GCN1L_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q92616] xref: UniProtKB:Q92616 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058073 ! GCN1L_HUMAN [Term] id: CCO:B0066426 name: GCN1L_HUMAN-Phosphoserine96 def: "Protein GCN1L_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q92616] xref: UniProtKB:Q92616 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058073 ! GCN1L_HUMAN [Term] id: CCO:B0066427 name: GCN1L_HUMAN-Phosphothreonine956 def: "Protein GCN1L_HUMAN with the residue 956 substituted with Phosphothreonine" [UniProtKB:Q92616] xref: UniProtKB:Q92616 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058073 ! GCN1L_HUMAN [Term] id: CCO:B0066428 name: GCR_HUMAN-Phosphoserine113 def: "Protein GCR_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:P04150] comment: By similarity xref: UniProtKB:P04150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054886 ! GCR_HUMAN [Term] id: CCO:B0066429 name: GCR_HUMAN-Phosphoserine141 def: "Protein GCR_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:P04150] comment: By similarity xref: UniProtKB:P04150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001236 ! glucocorticoid receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0054886 ! GCR_HUMAN [Term] id: CCO:B0066430 name: GCR_HUMAN-Phosphoserine203 def: "Protein GCR_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:P04150] xref: UniProtKB:P04150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054886 ! GCR_HUMAN [Term] id: CCO:B0066431 name: GCR_HUMAN-Phosphoserine211 def: "Protein GCR_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:P04150] xref: UniProtKB:P04150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054886 ! GCR_HUMAN [Term] id: CCO:B0066432 name: GCR_HUMAN-Phosphoserine226 def: "Protein GCR_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:P04150] comment: By similarity xref: UniProtKB:P04150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054886 ! GCR_HUMAN [Term] id: CCO:B0066433 name: GDE_HUMAN-Phosphotyrosine584 def: "Protein GDE_HUMAN with the residue 584 substituted with Phosphotyrosine" [UniProtKB:P35573] xref: UniProtKB:P35573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000604 ! glycogen debranching enzyme activity relationship: has_function CCO:F0000605 ! 4-alpha-glucanotransferase activity relationship: has_function CCO:F0000606 ! amylo-alpha-1,6-glucosidase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds relationship: has_function CCO:F0005808 ! cation binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001710 ! isoamylase complex relationship: transformation_of CCO:B0026523 ! GDE_HUMAN [Term] id: CCO:B0066434 name: GDIA_HUMAN-Phosphotyrosine333 def: "Protein GDIA_HUMAN with the residue 333 substituted with Phosphotyrosine" [UniProtKB:P31150] xref: UniProtKB:P31150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055233 ! GDIA_HUMAN [Term] id: CCO:B0066435 name: GDIA_HUMAN-Phosphotyrosine339 def: "Protein GDIA_HUMAN with the residue 339 substituted with Phosphotyrosine" [UniProtKB:P31150] comment: By similarity xref: UniProtKB:P31150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001397 ! GDP-dissociation inhibitor activity relationship: has_function CCO:F0001398 ! Rab GDP-dissociation inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055233 ! GDIA_HUMAN [Term] id: CCO:B0066436 name: GDIB_HUMAN-Phosphoserine61 def: "Protein GDIB_HUMAN with the residue 61 substituted with Phosphoserine" [UniProtKB:P50395] xref: UniProtKB:P50395 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055448 ! GDIB_HUMAN [Term] id: CCO:B0066437 name: GDIB_HUMAN-Phosphotyrosine203 def: "Protein GDIB_HUMAN with the residue 203 substituted with Phosphotyrosine" [UniProtKB:P50395] xref: UniProtKB:P50395 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001398 ! Rab GDP-dissociation inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055448 ! GDIB_HUMAN [Term] id: CCO:B0066438 name: GDIR2_HUMAN-N-acetylthreonine2 def: "Protein GDIR2_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P52566] xref: UniProtKB:P52566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055486 ! GDIR2_HUMAN [Term] id: CCO:B0066439 name: GDIR2_HUMAN-Phosphotyrosine24 def: "Protein GDIR2_HUMAN with the residue 24 substituted with Phosphotyrosine" [UniProtKB:P52566] xref: UniProtKB:P52566 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055486 ! GDIR2_HUMAN [Term] id: CCO:B0066440 name: GEMI2_HUMAN-Phosphothreonine48 def: "Protein GEMI2_HUMAN with the residue 48 substituted with Phosphothreonine" [UniProtKB:O14893] xref: UniProtKB:O14893 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0063282 ! GEMI2_HUMAN [Term] id: CCO:B0066441 name: GEMI4_HUMAN-Phosphoserine205 def: "Protein GEMI4_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:P57678] xref: UniProtKB:P57678 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0063087 ! GEMI4_HUMAN [Term] id: CCO:B0066442 name: GEMI5_HUMAN-Phosphoserine778 def: "Protein GEMI5_HUMAN with the residue 778 substituted with Phosphoserine" [UniProtKB:Q8TEQ6] xref: UniProtKB:Q8TEQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062979 ! GEMI5_HUMAN [Term] id: CCO:B0066443 name: GEMI5_HUMAN-Phosphothreonine807 def: "Protein GEMI5_HUMAN with the residue 807 substituted with Phosphothreonine" [UniProtKB:Q8TEQ6] xref: UniProtKB:Q8TEQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062979 ! GEMI5_HUMAN [Term] id: CCO:B0066444 name: GEMI5_HUMAN-Phosphoserine1417 def: "Protein GEMI5_HUMAN with the residue 1417 substituted with Phosphoserine" [UniProtKB:Q8TEQ6] comment: By similarity xref: UniProtKB:Q8TEQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062979 ! GEMI5_HUMAN [Term] id: CCO:B0066445 name: GFAP_HUMAN-Phosphothreonine110 def: "Protein GFAP_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:P14136] comment: By similarity xref: UniProtKB:P14136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0062814 ! GFAP_HUMAN [Term] id: CCO:B0066446 name: GFAP_HUMAN-Phosphothreonine383 def: "Protein GFAP_HUMAN with the residue 383 substituted with Phosphothreonine" [UniProtKB:P14136] comment: By similarity xref: UniProtKB:P14136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062814 ! GFAP_HUMAN [Term] id: CCO:B0066447 name: GIT1_HUMAN-Phosphoserine373 def: "Protein GIT1_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0066448 name: GIT1_HUMAN-Phosphotyrosine383 def: "Protein GIT1_HUMAN with the residue 383 substituted with Phosphotyrosine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0066449 name: GIT1_HUMAN-Phosphothreonine392 def: "Protein GIT1_HUMAN with the residue 392 substituted with Phosphothreonine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0066450 name: GIT1_HUMAN-Phosphoserine410 def: "Protein GIT1_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0066451 name: GIT1_HUMAN-Phosphoserine596 def: "Protein GIT1_HUMAN with the residue 596 substituted with Phosphoserine" [UniProtKB:Q9Y2X7] xref: UniProtKB:Q9Y2X7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:B0066452 name: GIT2_HUMAN-Phosphoserine394 def: "Protein GIT2_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066453 name: GIT2_HUMAN-Phosphoserine397 def: "Protein GIT2_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066454 name: GIT2_HUMAN-Phosphothreonine401 def: "Protein GIT2_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:Q14161] comment: By similarity xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001693 ! ARF GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066455 name: GIT2_HUMAN-Phosphoserine415 def: "Protein GIT2_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066456 name: GIT2_HUMAN-Phosphoserine418 def: "Protein GIT2_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066457 name: GIT2_HUMAN-Phosphoserine421 def: "Protein GIT2_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066458 name: GIT2_HUMAN-Phosphotyrosine484 def: "Protein GIT2_HUMAN with the residue 484 substituted with Phosphotyrosine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066459 name: GIT2_HUMAN-Phosphothreonine488 def: "Protein GIT2_HUMAN with the residue 488 substituted with Phosphothreonine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066460 name: GIT2_HUMAN-Phosphotyrosine492 def: "Protein GIT2_HUMAN with the residue 492 substituted with Phosphotyrosine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066461 name: GIT2_HUMAN-Phosphoserine496 def: "Protein GIT2_HUMAN with the residue 496 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066462 name: GIT2_HUMAN-Phosphoserine559 def: "Protein GIT2_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066463 name: GIT2_HUMAN-Phosphoserine586 def: "Protein GIT2_HUMAN with the residue 586 substituted with Phosphoserine" [UniProtKB:Q14161] comment: By similarity xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066464 name: GIT2_HUMAN-Phosphoserine614 def: "Protein GIT2_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:Q14161] xref: UniProtKB:Q14161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055967 ! GIT2_HUMAN [Term] id: CCO:B0066465 name: GKAP1_HUMAN-Phosphoserine23 def: "Protein GKAP1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q5VSY0] xref: UniProtKB:Q5VSY0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056643 ! GKAP1_HUMAN [Term] id: CCO:B0066466 name: GKAP1_HUMAN-Phosphoserine25 def: "Protein GKAP1_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q5VSY0] xref: UniProtKB:Q5VSY0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056643 ! GKAP1_HUMAN [Term] id: CCO:B0066467 name: GKAP1_HUMAN-Phosphoserine27 def: "Protein GKAP1_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q5VSY0] xref: UniProtKB:Q5VSY0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056643 ! GKAP1_HUMAN [Term] id: CCO:B0066468 name: GKAP1_HUMAN-Phosphoserine106 def: "Protein GKAP1_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q5VSY0] comment: by PKG; By similarity xref: UniProtKB:Q5VSY0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056643 ! GKAP1_HUMAN [Term] id: CCO:B0066469 name: GLRX2_HUMAN-cysteine77 def: "Protein GLRX2_HUMAN with the residue 77 substituted with cysteine" [UniProtKB:Q9NS18] comment: alternate; xref: UniProtKB:Q9NS18 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0002139 ! arsenate reductase (glutaredoxin) activity relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0002532 ! protein disulfide oxidoreductase activity relationship: has_function CCO:F0002535 ! glutathione disulfide oxidoreductase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008139 ! 2 iron, 2 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0058907 ! GLRX2_HUMAN [Term] id: CCO:B0066470 name: GLRX3_HUMAN-N-acetylalanine2 def: "Protein GLRX3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O76003] comment: By similarity xref: UniProtKB:O76003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0002532 ! protein disulfide oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0062932 ! GLRX3_HUMAN [Term] id: CCO:B0066471 name: GLUC_HUMAN-Arginine amide127 def: "Protein GLUC_HUMAN with the residue 127 substituted with Arginine amide" [UniProtKB:P01275] xref: UniProtKB:P01275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0054848 ! GLUC_HUMAN [Term] id: CCO:B0066472 name: GMCLL_HUMAN-Phosphotyrosine424 def: "Protein GMCLL_HUMAN with the residue 424 substituted with Phosphotyrosine" [UniProtKB:Q8NEA9] xref: UniProtKB:Q8NEA9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057588 ! GMCLL_HUMAN [Term] id: CCO:B0066473 name: GMEB1_HUMAN-Phosphoserine129 def: "Protein GMEB1_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q9Y692] xref: UniProtKB:Q9Y692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059401 ! GMEB1_HUMAN [Term] id: CCO:B0066474 name: GMFB_HUMAN-N-acetylserine2 def: "Protein GMFB_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P60983] comment: By similarity xref: UniProtKB:P60983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063366 ! GMFB_HUMAN [Term] id: CCO:B0066475 name: GMFB_HUMAN-Phosphotyrosine84 def: "Protein GMFB_HUMAN with the residue 84 substituted with Phosphotyrosine" [UniProtKB:P60983] xref: UniProtKB:P60983 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063366 ! GMFB_HUMAN [Term] id: CCO:B0066476 name: GMIP_HUMAN-Phosphoserine71 def: "Protein GMIP_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q9P107] comment: By similarity xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066477 name: GMIP_HUMAN-Phosphoserine234 def: "Protein GMIP_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q9P107] xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066478 name: GMIP_HUMAN-Phosphoserine243 def: "Protein GMIP_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:Q9P107] xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066479 name: GMIP_HUMAN-Phosphoserine437 def: "Protein GMIP_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q9P107] xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066480 name: GMIP_HUMAN-Phosphoserine441 def: "Protein GMIP_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:Q9P107] xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066481 name: GMIP_HUMAN-Phosphoserine914 def: "Protein GMIP_HUMAN with the residue 914 substituted with Phosphoserine" [UniProtKB:Q9P107] xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066482 name: GMIP_HUMAN-Phosphoserine919 def: "Protein GMIP_HUMAN with the residue 919 substituted with Phosphoserine" [UniProtKB:Q9P107] xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066483 name: GMIP_HUMAN-Phosphoserine923 def: "Protein GMIP_HUMAN with the residue 923 substituted with Phosphoserine" [UniProtKB:Q9P107] xref: UniProtKB:Q9P107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059036 ! GMIP_HUMAN [Term] id: CCO:B0066484 name: GNA15_HUMAN-ADP-ribosylarginine186 def: "Protein GNA15_HUMAN with the residue 186 substituted with ADP-ribosylarginine" [UniProtKB:P30679] comment: by cholera toxin; By similarity xref: UniProtKB:P30679 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0055225 ! GNA15_HUMAN [Term] id: CCO:B0066485 name: GNAI2_HUMAN-Phosphotyrosine69 def: "Protein GNAI2_HUMAN with the residue 69 substituted with Phosphotyrosine" [UniProtKB:P04899] xref: UniProtKB:P04899 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005754 ! GNAI2_HUMAN [Term] id: CCO:B0066486 name: GNAI3_HUMAN-Phosphotyrosine69 def: "Protein GNAI3_HUMAN with the residue 69 substituted with Phosphotyrosine" [UniProtKB:P08754] xref: UniProtKB:P08754 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0030269 ! GNAI3_HUMAN [Term] id: CCO:B0066487 name: GNAL_HUMAN-ADP-ribosylarginine188 def: "Protein GNAL_HUMAN with the residue 188 substituted with ADP-ribosylarginine" [UniProtKB:P38405] comment: by cholera toxin; By similarity xref: UniProtKB:P38405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027551 ! GNAL_HUMAN [Term] id: CCO:B0066488 name: GNAS1_HUMAN-Phosphoserine694 def: "Protein GNAS1_HUMAN with the residue 694 substituted with Phosphoserine" [UniProtKB:Q5JWF2] comment: By similarity xref: UniProtKB:Q5JWF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027554 ! GNAS1_HUMAN [Term] id: CCO:B0066489 name: GNAS1_HUMAN-ADP-ribosylarginine844 def: "Protein GNAS1_HUMAN with the residue 844 substituted with ADP-ribosylarginine" [UniProtKB:Q5JWF2] comment: by cholera toxin; By similarity xref: UniProtKB:Q5JWF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0027554 ! GNAS1_HUMAN [Term] id: CCO:B0066490 name: GNAS2_HUMAN-Phosphoserine51 def: "Protein GNAS2_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P63092] comment: By similarity xref: UniProtKB:P63092 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0004044 ! guanyl nucleotide binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: located_in CCO:C0001468 ! trans-Golgi network membrane relationship: transformation_of CCO:B0027550 ! GNAS2_HUMAN [Term] id: CCO:B0066491 name: GNAS2_HUMAN-ADP-ribosylarginine201 def: "Protein GNAS2_HUMAN with the residue 201 substituted with ADP-ribosylarginine" [UniProtKB:P63092] comment: by cholera toxin; By similarity xref: UniProtKB:P63092 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027550 ! GNAS2_HUMAN [Term] id: CCO:B0066492 name: GNL1_HUMAN-Phosphoserine32 def: "Protein GNL1_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066493 name: GNL1_HUMAN-Phosphoserine33 def: "Protein GNL1_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066494 name: GNL1_HUMAN-Phosphoserine34 def: "Protein GNL1_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066495 name: GNL1_HUMAN-Phosphothreonine48 def: "Protein GNL1_HUMAN with the residue 48 substituted with Phosphothreonine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066496 name: GNL1_HUMAN-Phosphothreonine50 def: "Protein GNL1_HUMAN with the residue 50 substituted with Phosphothreonine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066497 name: GNL1_HUMAN-Phosphoserine51 def: "Protein GNL1_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066498 name: GNL1_HUMAN-Phosphoserine68 def: "Protein GNL1_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066499 name: GNL1_HUMAN-Phosphoserine324 def: "Protein GNL1_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066500 name: GNL1_HUMAN-Phosphoserine561 def: "Protein GNL1_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066501 name: GNL1_HUMAN-Phosphoserine562 def: "Protein GNL1_HUMAN with the residue 562 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066502 name: GNL1_HUMAN-Phosphoserine563 def: "Protein GNL1_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:P36915] xref: UniProtKB:P36915 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055312 ! GNL1_HUMAN [Term] id: CCO:B0066503 name: GNMT_HUMAN-N-acetylvaline2 def: "Protein GNMT_HUMAN with the residue 2 substituted with N-acetylvaline" [UniProtKB:Q14749] comment: By similarity xref: UniProtKB:Q14749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001665 ! folic acid binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001757 ! N-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003612 ! glycine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0062843 ! GNMT_HUMAN [Term] id: CCO:B0066504 name: GNMT_HUMAN-Phosphoserine235 def: "Protein GNMT_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q14749] comment: By similarity xref: UniProtKB:Q14749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062843 ! GNMT_HUMAN [Term] id: CCO:B0066505 name: GO45_HUMAN-Phosphoserine353 def: "Protein GO45_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q9H2G9] xref: UniProtKB:Q9H2G9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000377 ! Golgi lumen relationship: transformation_of CCO:B0028029 ! GO45_HUMAN [Term] id: CCO:B0066506 name: GO45_HUMAN-Phosphothreonine369 def: "Protein GO45_HUMAN with the residue 369 substituted with Phosphothreonine" [UniProtKB:Q9H2G9] xref: UniProtKB:Q9H2G9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028029 ! GO45_HUMAN [Term] id: CCO:B0066507 name: GOGA2_HUMAN-Phosphoserine426 def: "Protein GOGA2_HUMAN with the residue 426 substituted with Phosphoserine" [UniProtKB:Q08379] xref: UniProtKB:Q08379 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006274 ! GOGA2_HUMAN [Term] id: CCO:B0066508 name: GOGB1_HUMAN-Phosphoserine17 def: "Protein GOGB1_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q14789] xref: UniProtKB:Q14789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000376 ! Golgi stack relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:B0066509 name: GOGB1_HUMAN-Phosphoserine38 def: "Protein GOGB1_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:Q14789] xref: UniProtKB:Q14789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:B0066510 name: GOGB1_HUMAN-Phosphothreonine45 def: "Protein GOGB1_HUMAN with the residue 45 substituted with Phosphothreonine" [UniProtKB:Q14789] xref: UniProtKB:Q14789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:B0066511 name: GOGB1_HUMAN-Phosphothreonine46 def: "Protein GOGB1_HUMAN with the residue 46 substituted with Phosphothreonine" [UniProtKB:Q14789] xref: UniProtKB:Q14789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:B0066512 name: GON1_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein GON1_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P01148] xref: UniProtKB:P01148 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054835 ! GON1_HUMAN [Term] id: CCO:B0066513 name: GON1_HUMAN-Glycine amide33 def: "Protein GON1_HUMAN with the residue 33 substituted with Glycine amide" [UniProtKB:P01148] xref: UniProtKB:P01148 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001480 ! luteinizing hormone-releasing factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0054835 ! GON1_HUMAN [Term] id: CCO:B0066514 name: GON2_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein GON2_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:O43555] comment: By similarity xref: UniProtKB:O43555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054489 ! GON2_HUMAN [Term] id: CCO:B0066515 name: GON2_HUMAN-Glycine amide33 def: "Protein GON2_HUMAN with the residue 33 substituted with Glycine amide" [UniProtKB:O43555] xref: UniProtKB:O43555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0054489 ! GON2_HUMAN [Term] id: CCO:B0066516 name: GON4L_HUMAN-Phosphoserine181 def: "Protein GON4L_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q3T8J9] xref: UniProtKB:Q3T8J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056276 ! GON4L_HUMAN [Term] id: CCO:B0066517 name: GON4L_HUMAN-Phosphoserine188 def: "Protein GON4L_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:Q3T8J9] xref: UniProtKB:Q3T8J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056276 ! GON4L_HUMAN [Term] id: CCO:B0066518 name: GOPC_HUMAN-Phosphotyrosine457 def: "Protein GOPC_HUMAN with the residue 457 substituted with Phosphotyrosine" [UniProtKB:Q9HD26] xref: UniProtKB:Q9HD26 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063033 ! GOPC_HUMAN [Term] id: CCO:B0066519 name: GOPC_HUMAN-Phosphotyrosine462 def: "Protein GOPC_HUMAN with the residue 462 substituted with Phosphotyrosine" [UniProtKB:Q9HD26] xref: UniProtKB:Q9HD26 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063033 ! GOPC_HUMAN [Term] id: CCO:B0066520 name: GORS2_HUMAN-Phosphothreonine433 def: "Protein GORS2_HUMAN with the residue 433 substituted with Phosphothreonine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0066521 name: GORS2_HUMAN-Phosphoserine436 def: "Protein GORS2_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0066522 name: GORS2_HUMAN-Phosphoserine449 def: "Protein GORS2_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q9H8Y8] xref: UniProtKB:Q9H8Y8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:B0066523 name: GP116_HUMAN-Phosphothreonine221 def: "Protein GP116_HUMAN with the residue 221 substituted with Phosphothreonine" [UniProtKB:Q8IZF2] xref: UniProtKB:Q8IZF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057402 ! GP116_HUMAN [Term] id: CCO:B0066524 name: GP125_HUMAN-Phosphothreonine208 def: "Protein GP125_HUMAN with the residue 208 substituted with Phosphothreonine" [UniProtKB:Q8IWK6] xref: UniProtKB:Q8IWK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057361 ! GP125_HUMAN [Term] id: CCO:B0066525 name: GP126_HUMAN-Phosphoserine1162 def: "Protein GP126_HUMAN with the residue 1162 substituted with Phosphoserine" [UniProtKB:Q86SQ4] xref: UniProtKB:Q86SQ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033405 ! GP126_HUMAN [Term] id: CCO:B0066526 name: GP126_HUMAN-Phosphoserine1165 def: "Protein GP126_HUMAN with the residue 1165 substituted with Phosphoserine" [UniProtKB:Q86SQ4] xref: UniProtKB:Q86SQ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0033405 ! GP126_HUMAN [Term] id: CCO:B0066527 name: GP128_HUMAN-Phosphotyrosine760 def: "Protein GP128_HUMAN with the residue 760 substituted with Phosphotyrosine" [UniProtKB:Q96K78] xref: UniProtKB:Q96K78 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058255 ! GP128_HUMAN [Term] id: CCO:B0066528 name: GP155_HUMAN-Phosphotyrosine451 def: "Protein GP155_HUMAN with the residue 451 substituted with Phosphotyrosine" [UniProtKB:Q7Z3F1] xref: UniProtKB:Q7Z3F1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057149 ! GP155_HUMAN [Term] id: CCO:B0066529 name: GP158_HUMAN-Phosphoserine904 def: "Protein GP158_HUMAN with the residue 904 substituted with Phosphoserine" [UniProtKB:Q5T848] comment: By similarity xref: UniProtKB:Q5T848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056596 ! GP158_HUMAN [Term] id: CCO:B0066530 name: GP1BA_HUMAN-Phosphotyrosine292 def: "Protein GP1BA_HUMAN with the residue 292 substituted with Phosphotyrosine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0066531 name: GP1BA_HUMAN-Phosphotyrosine294 def: "Protein GP1BA_HUMAN with the residue 294 substituted with Phosphotyrosine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0066532 name: GP1BA_HUMAN-Phosphotyrosine295 def: "Protein GP1BA_HUMAN with the residue 295 substituted with Phosphotyrosine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0066533 name: GP1BA_HUMAN-Phosphoserine603 def: "Protein GP1BA_HUMAN with the residue 603 substituted with Phosphoserine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0066534 name: GP1BA_HUMAN-Phosphoserine606 def: "Protein GP1BA_HUMAN with the residue 606 substituted with Phosphoserine" [UniProtKB:P07359] xref: UniProtKB:P07359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:B0066535 name: GP1BB_HUMAN-Phosphoserine191 def: "Protein GP1BB_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:P13224] comment: by PKA; xref: UniProtKB:P13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055010 ! GP1BB_HUMAN [Term] id: CCO:B0066536 name: GP1BB_HUMAN-Phosphothreonine193 def: "Protein GP1BB_HUMAN with the residue 193 substituted with Phosphothreonine" [UniProtKB:P13224] xref: UniProtKB:P13224 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001129 ! platelet alpha granule membrane relationship: transformation_of CCO:B0055010 ! GP1BB_HUMAN [Term] id: CCO:B0066537 name: GPBL1_HUMAN-Phosphoserine49 def: "Protein GPBL1_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:Q9HC44] xref: UniProtKB:Q9HC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058796 ! GPBL1_HUMAN [Term] id: CCO:B0066538 name: GPC5C_HUMAN-Phosphotyrosine324 def: "Protein GPC5C_HUMAN with the residue 324 substituted with Phosphotyrosine" [UniProtKB:Q9NQ84] xref: UniProtKB:Q9NQ84 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058864 ! GPC5C_HUMAN [Term] id: CCO:B0066539 name: GPC5C_HUMAN-Phosphoserine398 def: "Protein GPC5C_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:Q9NQ84] xref: UniProtKB:Q9NQ84 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0058864 ! GPC5C_HUMAN [Term] id: CCO:B0066540 name: GPN1_HUMAN-Phosphoserine312 def: "Protein GPN1_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q9HCN4] xref: UniProtKB:Q9HCN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058813 ! GPN1_HUMAN [Term] id: CCO:B0066541 name: GPN1_HUMAN-Phosphoserine314 def: "Protein GPN1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:Q9HCN4] xref: UniProtKB:Q9HCN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058813 ! GPN1_HUMAN [Term] id: CCO:B0066542 name: GPN1_HUMAN-Phosphoserine338 def: "Protein GPN1_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:Q9HCN4] xref: UniProtKB:Q9HCN4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058813 ! GPN1_HUMAN [Term] id: CCO:B0066543 name: GPR12_HUMAN-Phosphoserine330 def: "Protein GPR12_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P47775] comment: Potential xref: UniProtKB:P47775 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055385 ! GPR12_HUMAN [Term] id: CCO:B0066544 name: GPR12_HUMAN-Phosphoserine332 def: "Protein GPR12_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:P47775] comment: Potential xref: UniProtKB:P47775 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055385 ! GPR12_HUMAN [Term] id: CCO:B0066545 name: GPR39_HUMAN-Phosphoserine380 def: "Protein GPR39_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:O43194] comment: By similarity xref: UniProtKB:O43194 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054460 ! GPR39_HUMAN [Term] id: CCO:B0066546 name: GPR3_HUMAN-Phosphoserine324 def: "Protein GPR3_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:P46089] comment: Potential xref: UniProtKB:P46089 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055372 ! GPR3_HUMAN [Term] id: CCO:B0066547 name: GPR3_HUMAN-Phosphoserine326 def: "Protein GPR3_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:P46089] comment: Potential xref: UniProtKB:P46089 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055372 ! GPR3_HUMAN [Term] id: CCO:B0066548 name: GPR3_HUMAN-Phosphoserine328 def: "Protein GPR3_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P46089] comment: Potential xref: UniProtKB:P46089 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055372 ! GPR3_HUMAN [Term] id: CCO:B0066549 name: GPR6_HUMAN-Phosphoserine356 def: "Protein GPR6_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:P46095] comment: Potential xref: UniProtKB:P46095 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0000170 ! lysosphingolipid and lysophosphatidic acid receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055375 ! GPR6_HUMAN [Term] id: CCO:B0066550 name: GPR6_HUMAN-Phosphoserine358 def: "Protein GPR6_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:P46095] comment: Potential xref: UniProtKB:P46095 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055375 ! GPR6_HUMAN [Term] id: CCO:B0066551 name: GPR6_HUMAN-Phosphoserine360 def: "Protein GPR6_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:P46095] comment: Potential xref: UniProtKB:P46095 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055375 ! GPR6_HUMAN [Term] id: CCO:B0066552 name: GPSM1_HUMAN-Phosphoserine448 def: "Protein GPSM1_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:Q86YR5] xref: UniProtKB:Q86YR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057309 ! GPSM1_HUMAN [Term] id: CCO:B0066553 name: GPSM1_HUMAN-Phosphoserine469 def: "Protein GPSM1_HUMAN with the residue 469 substituted with Phosphoserine" [UniProtKB:Q86YR5] xref: UniProtKB:Q86YR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057309 ! GPSM1_HUMAN [Term] id: CCO:B0066554 name: GPSM1_HUMAN-Phosphoserine470 def: "Protein GPSM1_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:Q86YR5] xref: UniProtKB:Q86YR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057309 ! GPSM1_HUMAN [Term] id: CCO:B0066555 name: GPSM2_HUMAN-Phosphoserine476 def: "Protein GPSM2_HUMAN with the residue 476 substituted with Phosphoserine" [UniProtKB:P81274] xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0066556 name: GPSM2_HUMAN-Phosphothreonine479 def: "Protein GPSM2_HUMAN with the residue 479 substituted with Phosphothreonine" [UniProtKB:P81274] xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0066557 name: GPSM2_HUMAN-Phosphoserine534 def: "Protein GPSM2_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:P81274] xref: UniProtKB:P81274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:B0066558 name: GPTC8_HUMAN-Phosphoserine86 def: "Protein GPTC8_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066559 name: GPTC8_HUMAN-Phosphoserine237 def: "Protein GPTC8_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066560 name: GPTC8_HUMAN-Phosphothreonine242 def: "Protein GPTC8_HUMAN with the residue 242 substituted with Phosphothreonine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066561 name: GPTC8_HUMAN-Phosphoserine325 def: "Protein GPTC8_HUMAN with the residue 325 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066562 name: GPTC8_HUMAN-Phosphoserine327 def: "Protein GPTC8_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066563 name: GPTC8_HUMAN-Phosphoserine345 def: "Protein GPTC8_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066564 name: GPTC8_HUMAN-Phosphoserine498 def: "Protein GPTC8_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066565 name: GPTC8_HUMAN-Phosphoserine501 def: "Protein GPTC8_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066566 name: GPTC8_HUMAN-Phosphoserine596 def: "Protein GPTC8_HUMAN with the residue 596 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066567 name: GPTC8_HUMAN-Phosphoserine601 def: "Protein GPTC8_HUMAN with the residue 601 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066568 name: GPTC8_HUMAN-Phosphotyrosine618 def: "Protein GPTC8_HUMAN with the residue 618 substituted with Phosphotyrosine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066569 name: GPTC8_HUMAN-Phosphoserine620 def: "Protein GPTC8_HUMAN with the residue 620 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066570 name: GPTC8_HUMAN-Phosphoserine622 def: "Protein GPTC8_HUMAN with the residue 622 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066571 name: GPTC8_HUMAN-Phosphoserine663 def: "Protein GPTC8_HUMAN with the residue 663 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066572 name: GPTC8_HUMAN-Phosphoserine668 def: "Protein GPTC8_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066573 name: GPTC8_HUMAN-Phosphoserine694 def: "Protein GPTC8_HUMAN with the residue 694 substituted with Phosphoserine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066574 name: GPTC8_HUMAN-Phosphothreonine702 def: "Protein GPTC8_HUMAN with the residue 702 substituted with Phosphothreonine" [UniProtKB:Q9UKJ3] xref: UniProtKB:Q9UKJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:B0066575 name: GPX1_HUMAN-N6-acetyllysine146 def: "Protein GPX1_HUMAN with the residue 146 substituted with N6-acetyllysine" [UniProtKB:P07203] comment: By similarity xref: UniProtKB:P07203 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0000982 ! glutathione peroxidase activity relationship: has_function CCO:F0001897 ! selenium binding relationship: has_function CCO:F0001987 ! proteasome inhibitor activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0005835 ! glutathione binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0054910 ! GPX1_HUMAN [Term] id: CCO:B0066576 name: GRAP2_HUMAN-Phosphotyrosine45 def: "Protein GRAP2_HUMAN with the residue 45 substituted with Phosphotyrosine" [UniProtKB:O75791] xref: UniProtKB:O75791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054668 ! GRAP2_HUMAN [Term] id: CCO:B0066577 name: GRAP2_HUMAN-Phosphothreonine262 def: "Protein GRAP2_HUMAN with the residue 262 substituted with Phosphothreonine" [UniProtKB:O75791] xref: UniProtKB:O75791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054668 ! GRAP2_HUMAN [Term] id: CCO:B0066578 name: GRB10_HUMAN-Phosphoserine104 def: "Protein GRB10_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:Q13322] xref: UniProtKB:Q13322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:B0066579 name: GRB10_HUMAN-Phosphoserine150 def: "Protein GRB10_HUMAN with the residue 150 substituted with Phosphoserine" [UniProtKB:Q13322] comment: By similarity xref: UniProtKB:Q13322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:B0066580 name: GRB10_HUMAN-Phosphotyrosine404 def: "Protein GRB10_HUMAN with the residue 404 substituted with Phosphotyrosine" [UniProtKB:Q13322] xref: UniProtKB:Q13322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:B0066581 name: GRB10_HUMAN-Phosphoserine418 def: "Protein GRB10_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:Q13322] xref: UniProtKB:Q13322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:B0066582 name: GRB10_HUMAN-Phosphothreonine422 def: "Protein GRB10_HUMAN with the residue 422 substituted with Phosphothreonine" [UniProtKB:Q13322] xref: UniProtKB:Q13322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:B0066583 name: GRB10_HUMAN-Phosphoserine431 def: "Protein GRB10_HUMAN with the residue 431 substituted with Phosphoserine" [UniProtKB:Q13322] comment: By similarity xref: UniProtKB:Q13322 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:B0066584 name: GRB14_HUMAN-Phosphoserine372 def: "Protein GRB14_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q14449] comment: By similarity xref: UniProtKB:Q14449 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055984 ! GRB14_HUMAN [Term] id: CCO:B0066585 name: GRB2_HUMAN-Phosphothreonine211 def: "Protein GRB2_HUMAN with the residue 211 substituted with Phosphothreonine" [UniProtKB:P62993] xref: UniProtKB:P62993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:B0066586 name: GRB7_HUMAN-Phosphothreonine297 def: "Protein GRB7_HUMAN with the residue 297 substituted with Phosphothreonine" [UniProtKB:Q14451] comment: By similarity xref: UniProtKB:Q14451 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055985 ! GRB7_HUMAN [Term] id: CCO:B0066587 name: GRB7_HUMAN-Phosphoserine361 def: "Protein GRB7_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q14451] xref: UniProtKB:Q14451 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055985 ! GRB7_HUMAN [Term] id: CCO:B0066588 name: GRB7_HUMAN-Phosphoserine366 def: "Protein GRB7_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q14451] comment: By similarity xref: UniProtKB:Q14451 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055985 ! GRB7_HUMAN [Term] id: CCO:B0066589 name: GRDN_HUMAN-Phosphoserine1387 def: "Protein GRDN_HUMAN with the residue 1387 substituted with Phosphoserine" [UniProtKB:Q3V6T2] xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005850 ! protein kinase B binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066590 name: GRDN_HUMAN-Phosphoserine1417 def: "Protein GRDN_HUMAN with the residue 1417 substituted with Phosphoserine" [UniProtKB:Q3V6T2] comment: by PKB/AKT1; xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066591 name: GRDN_HUMAN-Phosphothreonine1559 def: "Protein GRDN_HUMAN with the residue 1559 substituted with Phosphothreonine" [UniProtKB:Q3V6T2] comment: By similarity xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066592 name: GRDN_HUMAN-Phosphothreonine1560 def: "Protein GRDN_HUMAN with the residue 1560 substituted with Phosphothreonine" [UniProtKB:Q3V6T2] comment: By similarity xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066593 name: GRDN_HUMAN-Phosphoserine1561 def: "Protein GRDN_HUMAN with the residue 1561 substituted with Phosphoserine" [UniProtKB:Q3V6T2] comment: By similarity xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066594 name: GRDN_HUMAN-Phosphothreonine1673 def: "Protein GRDN_HUMAN with the residue 1673 substituted with Phosphothreonine" [UniProtKB:Q3V6T2] xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066595 name: GRDN_HUMAN-Phosphoserine1675 def: "Protein GRDN_HUMAN with the residue 1675 substituted with Phosphoserine" [UniProtKB:Q3V6T2] comment: By similarity xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066596 name: GRDN_HUMAN-Phosphoserine1702 def: "Protein GRDN_HUMAN with the residue 1702 substituted with Phosphoserine" [UniProtKB:Q3V6T2] comment: By similarity xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066597 name: GRDN_HUMAN-Phosphoserine1837 def: "Protein GRDN_HUMAN with the residue 1837 substituted with Phosphoserine" [UniProtKB:Q3V6T2] xref: UniProtKB:Q3V6T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:B0066598 name: GRIA1_HUMAN-Phosphoserine645 def: "Protein GRIA1_HUMAN with the residue 645 substituted with Phosphoserine" [UniProtKB:P42261] comment: By similarity xref: UniProtKB:P42261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020627 ! GRIA1_HUMAN [Term] id: CCO:B0066599 name: GRIA1_HUMAN-Phosphoserine710 def: "Protein GRIA1_HUMAN with the residue 710 substituted with Phosphoserine" [UniProtKB:P42261] comment: By similarity xref: UniProtKB:P42261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001695 ! glutamate receptor activity relationship: has_function CCO:F0002734 ! kainate selective glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0020627 ! GRIA1_HUMAN [Term] id: CCO:B0066600 name: GRIA1_HUMAN-Phosphoserine849 def: "Protein GRIA1_HUMAN with the residue 849 substituted with Phosphoserine" [UniProtKB:P42261] comment: By similarity xref: UniProtKB:P42261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020627 ! GRIA1_HUMAN [Term] id: CCO:B0066601 name: GRIA1_HUMAN-Phosphoserine863 def: "Protein GRIA1_HUMAN with the residue 863 substituted with Phosphoserine" [UniProtKB:P42261] comment: By similarity xref: UniProtKB:P42261 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020627 ! GRIA1_HUMAN [Term] id: CCO:B0066602 name: GRIA2_HUMAN-Phosphoserine683 def: "Protein GRIA2_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:P42262] comment: by PKC; By similarity xref: UniProtKB:P42262 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020601 ! GRIA2_HUMAN [Term] id: CCO:B0066603 name: GRIA2_HUMAN-Phosphoserine717 def: "Protein GRIA2_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:P42262] comment: by PKG; By similarity xref: UniProtKB:P42262 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020601 ! GRIA2_HUMAN [Term] id: CCO:B0066604 name: GRIA2_HUMAN-Phosphotyrosine869 def: "Protein GRIA2_HUMAN with the residue 869 substituted with Phosphotyrosine" [UniProtKB:P42262] comment: By similarity xref: UniProtKB:P42262 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020601 ! GRIA2_HUMAN [Term] id: CCO:B0066605 name: GRIA2_HUMAN-Phosphotyrosine876 def: "Protein GRIA2_HUMAN with the residue 876 substituted with Phosphotyrosine" [UniProtKB:P42262] comment: By similarity xref: UniProtKB:P42262 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020601 ! GRIA2_HUMAN [Term] id: CCO:B0066606 name: GRIA2_HUMAN-Phosphoserine880 def: "Protein GRIA2_HUMAN with the residue 880 substituted with Phosphoserine" [UniProtKB:P42262] comment: By similarity xref: UniProtKB:P42262 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001312 ! alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001695 ! glutamate receptor activity relationship: has_function CCO:F0002734 ! kainate selective glutamate receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0020601 ! GRIA2_HUMAN [Term] id: CCO:B0066607 name: GRIA3_HUMAN-Phosphotyrosine877 def: "Protein GRIA3_HUMAN with the residue 877 substituted with Phosphotyrosine" [UniProtKB:P42263] comment: By similarity xref: UniProtKB:P42263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020622 ! GRIA3_HUMAN [Term] id: CCO:B0066608 name: GRIA3_HUMAN-Phosphotyrosine887 def: "Protein GRIA3_HUMAN with the residue 887 substituted with Phosphotyrosine" [UniProtKB:P42263] comment: By similarity xref: UniProtKB:P42263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0020622 ! GRIA3_HUMAN [Term] id: CCO:B0066609 name: GRIK1_HUMAN-Phosphoserine725 def: "Protein GRIK1_HUMAN with the residue 725 substituted with Phosphoserine" [UniProtKB:P39086] comment: by PKC; Potential xref: UniProtKB:P39086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020614 ! GRIK1_HUMAN [Term] id: CCO:B0066610 name: GRIK1_HUMAN-Phosphothreonine761 def: "Protein GRIK1_HUMAN with the residue 761 substituted with Phosphothreonine" [UniProtKB:P39086] comment: by PKC; Potential xref: UniProtKB:P39086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020614 ! GRIK1_HUMAN [Term] id: CCO:B0066611 name: GRIK3_HUMAN-Phosphotyrosine544 def: "Protein GRIK3_HUMAN with the residue 544 substituted with Phosphotyrosine" [UniProtKB:Q13003] xref: UniProtKB:Q13003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020605 ! GRIK3_HUMAN [Term] id: CCO:B0066612 name: GRIPE_HUMAN-Phosphothreonine754 def: "Protein GRIPE_HUMAN with the residue 754 substituted with Phosphothreonine" [UniProtKB:Q6GYQ0] xref: UniProtKB:Q6GYQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056736 ! GRIPE_HUMAN [Term] id: CCO:B0066613 name: GRIPE_HUMAN-Phosphoserine773 def: "Protein GRIPE_HUMAN with the residue 773 substituted with Phosphoserine" [UniProtKB:Q6GYQ0] xref: UniProtKB:Q6GYQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056736 ! GRIPE_HUMAN [Term] id: CCO:B0066614 name: GRIPE_HUMAN-Phosphothreonine778 def: "Protein GRIPE_HUMAN with the residue 778 substituted with Phosphothreonine" [UniProtKB:Q6GYQ0] xref: UniProtKB:Q6GYQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056736 ! GRIPE_HUMAN [Term] id: CCO:B0066615 name: GRIPE_HUMAN-Phosphoserine797 def: "Protein GRIPE_HUMAN with the residue 797 substituted with Phosphoserine" [UniProtKB:Q6GYQ0] xref: UniProtKB:Q6GYQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056736 ! GRIPE_HUMAN [Term] id: CCO:B0066616 name: GRIPE_HUMAN-Phosphoserine860 def: "Protein GRIPE_HUMAN with the residue 860 substituted with Phosphoserine" [UniProtKB:Q6GYQ0] xref: UniProtKB:Q6GYQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056736 ! GRIPE_HUMAN [Term] id: CCO:B0066617 name: GRIPE_HUMAN-Phosphoserine861 def: "Protein GRIPE_HUMAN with the residue 861 substituted with Phosphoserine" [UniProtKB:Q6GYQ0] xref: UniProtKB:Q6GYQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056736 ! GRIPE_HUMAN [Term] id: CCO:B0066618 name: GRIPE_HUMAN-Phosphoserine864 def: "Protein GRIPE_HUMAN with the residue 864 substituted with Phosphoserine" [UniProtKB:Q6GYQ0] xref: UniProtKB:Q6GYQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056736 ! GRIPE_HUMAN [Term] id: CCO:B0066619 name: GRK5_HUMAN-Phosphoserine484 def: "Protein GRK5_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:P34947] comment: by autocatalysis; By similarity xref: UniProtKB:P34947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055271 ! GRK5_HUMAN [Term] id: CCO:B0066620 name: GRK5_HUMAN-Phosphothreonine485 def: "Protein GRK5_HUMAN with the residue 485 substituted with Phosphothreonine" [UniProtKB:P34947] comment: by autocatalysis; By similarity xref: UniProtKB:P34947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055271 ! GRK5_HUMAN [Term] id: CCO:B0066621 name: GRK6_HUMAN-Phosphoserine484 def: "Protein GRK6_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:P43250] comment: by autocatalysis; By similarity xref: UniProtKB:P43250 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055361 ! GRK6_HUMAN [Term] id: CCO:B0066622 name: GRK6_HUMAN-Phosphothreonine485 def: "Protein GRK6_HUMAN with the residue 485 substituted with Phosphothreonine" [UniProtKB:P43250] comment: by autocatalysis; By similarity xref: UniProtKB:P43250 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055361 ! GRK6_HUMAN [Term] id: CCO:B0066623 name: GRK7_HUMAN-Cysteine methyl ester550 def: "Protein GRK7_HUMAN with the residue 550 substituted with Cysteine methyl ester" [UniProtKB:Q8WTQ7] comment: Potential xref: UniProtKB:Q8WTQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057968 ! GRK7_HUMAN [Term] id: CCO:B0066624 name: GRLF1_HUMAN-Phosphoserine589 def: "Protein GRLF1_HUMAN with the residue 589 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0066625 name: GRLF1_HUMAN-Phosphothreonine963 def: "Protein GRLF1_HUMAN with the residue 963 substituted with Phosphothreonine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0066626 name: GRLF1_HUMAN-Phosphoserine975 def: "Protein GRLF1_HUMAN with the residue 975 substituted with Phosphoserine" [UniProtKB:Q9NRY4] xref: UniProtKB:Q9NRY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002160 ! GRLF1_HUMAN [Term] id: CCO:B0066627 name: GRM1_HUMAN-Phosphotyrosine1109 def: "Protein GRM1_HUMAN with the residue 1109 substituted with Phosphotyrosine" [UniProtKB:Q13255] xref: UniProtKB:Q13255 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0042245 ! GRM1_HUMAN [Term] id: CCO:B0066628 name: GRM1_HUMAN-Phosphotyrosine1111 def: "Protein GRM1_HUMAN with the residue 1111 substituted with Phosphotyrosine" [UniProtKB:Q13255] xref: UniProtKB:Q13255 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0042245 ! GRM1_HUMAN [Term] id: CCO:B0066629 name: GRP1_HUMAN-Phosphothreonine184 def: "Protein GRP1_HUMAN with the residue 184 substituted with Phosphothreonine" [UniProtKB:O95267] comment: by PKC; xref: UniProtKB:O95267 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054743 ! GRP1_HUMAN [Term] id: CCO:B0066630 name: GRP2_HUMAN-Phosphoserine116 def: "Protein GRP2_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q7LDG7] comment: By similarity xref: UniProtKB:Q7LDG7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0057123 ! GRP2_HUMAN [Term] id: CCO:B0066631 name: GRP2_HUMAN-Phosphoserine117 def: "Protein GRP2_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q7LDG7] comment: By similarity xref: UniProtKB:Q7LDG7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057123 ! GRP2_HUMAN [Term] id: CCO:B0066632 name: GRP75_HUMAN-Phosphotyrosine568 def: "Protein GRP75_HUMAN with the residue 568 substituted with Phosphotyrosine" [UniProtKB:P38646] xref: UniProtKB:P38646 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:B0066633 name: GRP_HUMAN-Methionine amide50 def: "Protein GRP_HUMAN with the residue 50 substituted with Methionine amide" [UniProtKB:P07492] xref: UniProtKB:P07492 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054913 ! GRP_HUMAN [Term] id: CCO:B0066634 name: GSE1_HUMAN-Phosphoserine826 def: "Protein GSE1_HUMAN with the residue 826 substituted with Phosphoserine" [UniProtKB:Q14687] xref: UniProtKB:Q14687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005595 ! GSE1_HUMAN [Term] id: CCO:B0066635 name: GSE1_HUMAN-Phosphoserine828 def: "Protein GSE1_HUMAN with the residue 828 substituted with Phosphoserine" [UniProtKB:Q14687] xref: UniProtKB:Q14687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005595 ! GSE1_HUMAN [Term] id: CCO:B0066636 name: GSE1_HUMAN-Phosphoserine909 def: "Protein GSE1_HUMAN with the residue 909 substituted with Phosphoserine" [UniProtKB:Q14687] xref: UniProtKB:Q14687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005595 ! GSE1_HUMAN [Term] id: CCO:B0066637 name: GSE1_HUMAN-Phosphoserine1101 def: "Protein GSE1_HUMAN with the residue 1101 substituted with Phosphoserine" [UniProtKB:Q14687] xref: UniProtKB:Q14687 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005595 ! GSE1_HUMAN [Term] id: CCO:B0066638 name: GSUB_HUMAN-Phosphothreonine68 def: "Protein GSUB_HUMAN with the residue 68 substituted with Phosphothreonine" [UniProtKB:O96001] comment: by PKG; Probable xref: UniProtKB:O96001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054818 ! GSUB_HUMAN [Term] id: CCO:B0066639 name: GSUB_HUMAN-Phosphothreonine119 def: "Protein GSUB_HUMAN with the residue 119 substituted with Phosphothreonine" [UniProtKB:O96001] comment: by PKG; Probable xref: UniProtKB:O96001 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001221 ! type 1 serine/threonine specific protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0054818 ! GSUB_HUMAN [Term] id: CCO:B0066640 name: GT2D1_HUMAN-Phosphoserine448 def: "Protein GT2D1_HUMAN with the residue 448 substituted with Phosphoserine" [UniProtKB:Q9UHL9] xref: UniProtKB:Q9UHL9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027079 ! GT2D1_HUMAN [Term] id: CCO:B0066641 name: GT2D1_HUMAN-Phosphoserine654 def: "Protein GT2D1_HUMAN with the residue 654 substituted with Phosphoserine" [UniProtKB:Q9UHL9] xref: UniProtKB:Q9UHL9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027079 ! GT2D1_HUMAN [Term] id: CCO:B0066642 name: GTF2I_HUMAN-N-acetylalanine2 def: "Protein GTF2I_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066643 name: GTF2I_HUMAN-Phosphoserine103 def: "Protein GTF2I_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066644 name: GTF2I_HUMAN-Phosphoserine207 def: "Protein GTF2I_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066645 name: GTF2I_HUMAN-Phosphoserine210 def: "Protein GTF2I_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066646 name: GTF2I_HUMAN-Phosphotyrosine248 def: "Protein GTF2I_HUMAN with the residue 248 substituted with Phosphotyrosine" [UniProtKB:P78347] comment: by BTK; xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066647 name: GTF2I_HUMAN-Phosphotyrosine318 def: "Protein GTF2I_HUMAN with the residue 318 substituted with Phosphotyrosine" [UniProtKB:P78347] comment: by BTK; Probable xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066648 name: GTF2I_HUMAN-Phosphotyrosine398 def: "Protein GTF2I_HUMAN with the residue 398 substituted with Phosphotyrosine" [UniProtKB:P78347] comment: by BTK; xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066649 name: GTF2I_HUMAN-Phosphotyrosine503 def: "Protein GTF2I_HUMAN with the residue 503 substituted with Phosphotyrosine" [UniProtKB:P78347] comment: by BTK; xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066650 name: GTF2I_HUMAN-Phosphoserine515 def: "Protein GTF2I_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066651 name: GTF2I_HUMAN-Phosphoserine517 def: "Protein GTF2I_HUMAN with the residue 517 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066652 name: GTF2I_HUMAN-Phosphothreonine558 def: "Protein GTF2I_HUMAN with the residue 558 substituted with Phosphothreonine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066653 name: GTF2I_HUMAN-Phosphoserine668 def: "Protein GTF2I_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066654 name: GTF2I_HUMAN-Phosphoserine674 def: "Protein GTF2I_HUMAN with the residue 674 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066655 name: GTF2I_HUMAN-Phosphoserine679 def: "Protein GTF2I_HUMAN with the residue 679 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066656 name: GTF2I_HUMAN-Phosphothreonine687 def: "Protein GTF2I_HUMAN with the residue 687 substituted with Phosphothreonine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066657 name: GTF2I_HUMAN-Phosphoserine823 def: "Protein GTF2I_HUMAN with the residue 823 substituted with Phosphoserine" [UniProtKB:P78347] xref: UniProtKB:P78347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:B0066658 name: GTSE1_HUMAN-Phosphoserine477 def: "Protein GTSE1_HUMAN with the residue 477 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066659 name: GTSE1_HUMAN-Phosphothreonine479 def: "Protein GTSE1_HUMAN with the residue 479 substituted with Phosphothreonine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066660 name: GTSE1_HUMAN-Phosphoserine480 def: "Protein GTSE1_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066661 name: GTSE1_HUMAN-Phosphoserine509 def: "Protein GTSE1_HUMAN with the residue 509 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066662 name: GTSE1_HUMAN-Phosphothreonine513 def: "Protein GTSE1_HUMAN with the residue 513 substituted with Phosphothreonine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066663 name: GTSE1_HUMAN-Phosphoserine516 def: "Protein GTSE1_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066664 name: GTSE1_HUMAN-Phosphoserine520 def: "Protein GTSE1_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066665 name: GTSE1_HUMAN-Phosphothreonine526 def: "Protein GTSE1_HUMAN with the residue 526 substituted with Phosphothreonine" [UniProtKB:Q9NYZ3] xref: UniProtKB:Q9NYZ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002180 ! GTSE1_HUMAN [Term] id: CCO:B0066666 name: GYS1_HUMAN-Phosphoserine8 def: "Protein GYS1_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:P13807] comment: by PKA; By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066667 name: GYS1_HUMAN-Phosphoserine11 def: "Protein GYS1_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066668 name: GYS1_HUMAN-Phosphoserine641 def: "Protein GYS1_HUMAN with the residue 641 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066669 name: GYS1_HUMAN-Phosphoserine645 def: "Protein GYS1_HUMAN with the residue 645 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066670 name: GYS1_HUMAN-Phosphoserine649 def: "Protein GYS1_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066671 name: GYS1_HUMAN-Phosphoserine653 def: "Protein GYS1_HUMAN with the residue 653 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066672 name: GYS1_HUMAN-Phosphoserine657 def: "Protein GYS1_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066673 name: GYS1_HUMAN-Phosphoserine698 def: "Protein GYS1_HUMAN with the residue 698 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066674 name: GYS1_HUMAN-Phosphoserine710 def: "Protein GYS1_HUMAN with the residue 710 substituted with Phosphoserine" [UniProtKB:P13807] comment: By similarity xref: UniProtKB:P13807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:B0066675 name: H12_HUMAN-N-acetylserine2 def: "Protein H12_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P16403] xref: UniProtKB:P16403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063188 ! H12_HUMAN [Term] id: CCO:B0066676 name: H12_HUMAN-Phosphothreonine31 def: "Protein H12_HUMAN with the residue 31 substituted with Phosphothreonine" [UniProtKB:P16403] xref: UniProtKB:P16403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063188 ! H12_HUMAN [Term] id: CCO:B0066677 name: H12_HUMAN-Phosphoserine36 def: "Protein H12_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P16403] xref: UniProtKB:P16403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063188 ! H12_HUMAN [Term] id: CCO:B0066678 name: H12_HUMAN-Phosphoserine173 def: "Protein H12_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:P16403] xref: UniProtKB:P16403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0063188 ! H12_HUMAN [Term] id: CCO:B0066679 name: H1X_HUMAN-N-acetylserine2 def: "Protein H1X_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q92522] xref: UniProtKB:Q92522 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0063190 ! H1X_HUMAN [Term] id: CCO:B0066680 name: H1X_HUMAN-Phosphoserine2 def: "Protein H1X_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q92522] xref: UniProtKB:Q92522 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063190 ! H1X_HUMAN [Term] id: CCO:B0066681 name: H1X_HUMAN-Phosphoserine31 def: "Protein H1X_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q92522] xref: UniProtKB:Q92522 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063190 ! H1X_HUMAN [Term] id: CCO:B0066682 name: H2A1C_HUMAN-N-acetylserine2 def: "Protein H2A1C_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q93077] xref: UniProtKB:Q93077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0021917 ! H2A1C_HUMAN [Term] id: CCO:B0066683 name: H2A1C_HUMAN-Phosphoserine2 def: "Protein H2A1C_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q93077] xref: UniProtKB:Q93077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021917 ! H2A1C_HUMAN [Term] id: CCO:B0066684 name: H2A1C_HUMAN-Citrulline4 def: "Protein H2A1C_HUMAN with the residue 4 substituted with Citrulline" [UniProtKB:Q93077] comment: alternate; xref: UniProtKB:Q93077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021917 ! H2A1C_HUMAN [Term] id: CCO:B0066685 name: H2A1C_HUMAN-dimethylarginine4 def: "Protein H2A1C_HUMAN with the residue 4 substituted with dimethylarginine" [UniProtKB:Q93077] comment: alternate; By similarity xref: UniProtKB:Q93077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021917 ! H2A1C_HUMAN [Term] id: CCO:B0066686 name: H2A1C_HUMAN-N6-acetyllysine6 def: "Protein H2A1C_HUMAN with the residue 6 substituted with N6-acetyllysine" [UniProtKB:Q93077] xref: UniProtKB:Q93077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021917 ! H2A1C_HUMAN [Term] id: CCO:B0066687 name: H2A1C_HUMAN-Phosphothreonine121 def: "Protein H2A1C_HUMAN with the residue 121 substituted with Phosphothreonine" [UniProtKB:Q93077] comment: Probable xref: UniProtKB:Q93077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021917 ! H2A1C_HUMAN [Term] id: CCO:B0066688 name: H2A2A_HUMAN-N-acetylserine2 def: "Protein H2A2A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q6FI13] xref: UniProtKB:Q6FI13 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021914 ! H2A2A_HUMAN [Term] id: CCO:B0066689 name: H2A2A_HUMAN-Phosphoserine2 def: "Protein H2A2A_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q6FI13] xref: UniProtKB:Q6FI13 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021914 ! H2A2A_HUMAN [Term] id: CCO:B0066690 name: H2A2A_HUMAN-Citrulline4 def: "Protein H2A2A_HUMAN with the residue 4 substituted with Citrulline" [UniProtKB:Q6FI13] comment: alternate; xref: UniProtKB:Q6FI13 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021914 ! H2A2A_HUMAN [Term] id: CCO:B0066691 name: H2A2A_HUMAN-dimethylarginine4 def: "Protein H2A2A_HUMAN with the residue 4 substituted with dimethylarginine" [UniProtKB:Q6FI13] comment: alternate; By similarity xref: UniProtKB:Q6FI13 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021914 ! H2A2A_HUMAN [Term] id: CCO:B0066692 name: H2A2A_HUMAN-N6-acetyllysine6 def: "Protein H2A2A_HUMAN with the residue 6 substituted with N6-acetyllysine" [UniProtKB:Q6FI13] xref: UniProtKB:Q6FI13 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021914 ! H2A2A_HUMAN [Term] id: CCO:B0066693 name: H2A2A_HUMAN-Phosphothreonine121 def: "Protein H2A2A_HUMAN with the residue 121 substituted with Phosphothreonine" [UniProtKB:Q6FI13] comment: Probable xref: UniProtKB:Q6FI13 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021914 ! H2A2A_HUMAN [Term] id: CCO:B0066694 name: H2AY_HUMAN-N6-methyllysine18 def: "Protein H2AY_HUMAN with the residue 18 substituted with N6-methyllysine" [UniProtKB:O75367] xref: UniProtKB:O75367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000183 ! Barr body relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0054625 ! H2AY_HUMAN [Term] id: CCO:B0066695 name: H2AY_HUMAN-N6,N6-dimethyllysine123 def: "Protein H2AY_HUMAN with the residue 123 substituted with N6,N6-dimethyllysine" [UniProtKB:O75367] comment: Probable xref: UniProtKB:O75367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054625 ! H2AY_HUMAN [Term] id: CCO:B0066696 name: H2AY_HUMAN-Phosphothreonine129 def: "Protein H2AY_HUMAN with the residue 129 substituted with Phosphothreonine" [UniProtKB:O75367] xref: UniProtKB:O75367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054625 ! H2AY_HUMAN [Term] id: CCO:B0066697 name: H2AY_HUMAN-Phosphothreonine178 def: "Protein H2AY_HUMAN with the residue 178 substituted with Phosphothreonine" [UniProtKB:O75367] xref: UniProtKB:O75367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054625 ! H2AY_HUMAN [Term] id: CCO:B0066698 name: H2B1B_HUMAN-N6-acetyllysine6 def: "Protein H2B1B_HUMAN with the residue 6 substituted with N6-acetyllysine" [UniProtKB:P33778] xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066699 name: H2B1B_HUMAN-N6-acetyllysine12 def: "Protein H2B1B_HUMAN with the residue 12 substituted with N6-acetyllysine" [UniProtKB:P33778] xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066700 name: H2B1B_HUMAN-N6-acetyllysine13 def: "Protein H2B1B_HUMAN with the residue 13 substituted with N6-acetyllysine" [UniProtKB:P33778] xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066701 name: H2B1B_HUMAN-Phosphoserine15 def: "Protein H2B1B_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:P33778] comment: by STK4; xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066702 name: H2B1B_HUMAN-N6-acetyllysine16 def: "Protein H2B1B_HUMAN with the residue 16 substituted with N6-acetyllysine" [UniProtKB:P33778] xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066703 name: H2B1B_HUMAN-N6-acetyllysine17 def: "Protein H2B1B_HUMAN with the residue 17 substituted with N6-acetyllysine" [UniProtKB:P33778] xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066704 name: H2B1B_HUMAN-N6-acetyllysine21 def: "Protein H2B1B_HUMAN with the residue 21 substituted with N6-acetyllysine" [UniProtKB:P33778] xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066705 name: H2B1B_HUMAN-N6-acetyllysine24 def: "Protein H2B1B_HUMAN with the residue 24 substituted with N6-acetyllysine" [UniProtKB:P33778] comment: By similarity xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066706 name: H2B1B_HUMAN-N6-methylated lysine47 def: "Protein H2B1B_HUMAN with the residue 47 substituted with N6-methylated lysine" [UniProtKB:P33778] comment: Probable xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066707 name: H2B1B_HUMAN-N6-methylated lysine58 def: "Protein H2B1B_HUMAN with the residue 58 substituted with N6-methylated lysine" [UniProtKB:P33778] comment: Probable xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066708 name: H2B1B_HUMAN-N6-acetyllysine109 def: "Protein H2B1B_HUMAN with the residue 109 substituted with N6-acetyllysine" [UniProtKB:P33778] comment: alternate; xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066709 name: H2B1B_HUMAN-lysine109 def: "Protein H2B1B_HUMAN with the residue 109 substituted with lysine" [UniProtKB:P33778] comment: alternate; Probable xref: UniProtKB:P33778 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:B0066710 name: H2B1H_HUMAN-N6-acetyllysine6 def: "Protein H2B1H_HUMAN with the residue 6 substituted with N6-acetyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066711 name: H2B1H_HUMAN-N6-acetyllysine12 def: "Protein H2B1H_HUMAN with the residue 12 substituted with N6-acetyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066712 name: H2B1H_HUMAN-N6-acetyllysine13 def: "Protein H2B1H_HUMAN with the residue 13 substituted with N6-acetyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066713 name: H2B1H_HUMAN-Phosphoserine15 def: "Protein H2B1H_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q93079] comment: by STK4; xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066714 name: H2B1H_HUMAN-N6-acetyllysine16 def: "Protein H2B1H_HUMAN with the residue 16 substituted with N6-acetyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066715 name: H2B1H_HUMAN-N6-acetyllysine17 def: "Protein H2B1H_HUMAN with the residue 17 substituted with N6-acetyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066716 name: H2B1H_HUMAN-N6-acetyllysine21 def: "Protein H2B1H_HUMAN with the residue 21 substituted with N6-acetyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066717 name: H2B1H_HUMAN-N6-acetyllysine24 def: "Protein H2B1H_HUMAN with the residue 24 substituted with N6-acetyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066718 name: H2B1H_HUMAN-N6-methyllysine47 def: "Protein H2B1H_HUMAN with the residue 47 substituted with N6-methyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066719 name: H2B1H_HUMAN-N6,N6-dimethyllysine58 def: "Protein H2B1H_HUMAN with the residue 58 substituted with N6,N6-dimethyllysine" [UniProtKB:Q93079] xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066720 name: H2B1H_HUMAN-N6-acetyllysine109 def: "Protein H2B1H_HUMAN with the residue 109 substituted with N6-acetyllysine" [UniProtKB:Q93079] comment: alternate; xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066721 name: H2B1H_HUMAN-N6-methyllysine109 def: "Protein H2B1H_HUMAN with the residue 109 substituted with N6-methyllysine" [UniProtKB:Q93079] comment: alternate; xref: UniProtKB:Q93079 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063352 ! H2B1H_HUMAN [Term] id: CCO:B0066722 name: H31T_HUMAN-Phosphothreonine4 def: "Protein H31T_HUMAN with the residue 4 substituted with Phosphothreonine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066723 name: H31T_HUMAN-N6-methylated lysine5 def: "Protein H31T_HUMAN with the residue 5 substituted with N6-methylated lysine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066724 name: H31T_HUMAN-Citrulline9 def: "Protein H31T_HUMAN with the residue 9 substituted with Citrulline" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066725 name: H31T_HUMAN-dimethylarginine9 def: "Protein H31T_HUMAN with the residue 9 substituted with dimethylarginine" [UniProtKB:Q16695] comment: by PRMT5; alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066726 name: H31T_HUMAN-N6-acetyllysine10 def: "Protein H31T_HUMAN with the residue 10 substituted with N6-acetyllysine" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066727 name: H31T_HUMAN-lysine10 def: "Protein H31T_HUMAN with the residue 10 substituted with lysine" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066728 name: H31T_HUMAN-Phosphoserine11 def: "Protein H31T_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066729 name: H31T_HUMAN-Phosphothreonine12 def: "Protein H31T_HUMAN with the residue 12 substituted with Phosphothreonine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066730 name: H31T_HUMAN-N6-acetyllysine15 def: "Protein H31T_HUMAN with the residue 15 substituted with N6-acetyllysine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066731 name: H31T_HUMAN-dimethylarginine18 def: "Protein H31T_HUMAN with the residue 18 substituted with dimethylarginine" [UniProtKB:Q16695] comment: by CARM1; alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066732 name: H31T_HUMAN-Citrulline18 def: "Protein H31T_HUMAN with the residue 18 substituted with Citrulline" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000113 ! nucleosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066733 name: H31T_HUMAN-N6-acetyllysine19 def: "Protein H31T_HUMAN with the residue 19 substituted with N6-acetyllysine" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066734 name: H31T_HUMAN-lysine19 def: "Protein H31T_HUMAN with the residue 19 substituted with lysine" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066735 name: H31T_HUMAN-N6-acetyllysine24 def: "Protein H31T_HUMAN with the residue 24 substituted with N6-acetyllysine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066736 name: H31T_HUMAN-N6-acetyllysine28 def: "Protein H31T_HUMAN with the residue 28 substituted with N6-acetyllysine" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066737 name: H31T_HUMAN-lysine28 def: "Protein H31T_HUMAN with the residue 28 substituted with lysine" [UniProtKB:Q16695] comment: alternate; xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066738 name: H31T_HUMAN-Phosphoserine29 def: "Protein H31T_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066739 name: H31T_HUMAN-N6-acetyllysine37 def: "Protein H31T_HUMAN with the residue 37 substituted with N6-acetyllysine" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066740 name: H31T_HUMAN-lysine37 def: "Protein H31T_HUMAN with the residue 37 substituted with lysine" [UniProtKB:Q16695] comment: alternate; By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066741 name: H31T_HUMAN-N6-methylated lysine65 def: "Protein H31T_HUMAN with the residue 65 substituted with N6-methylated lysine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066742 name: H31T_HUMAN-N6-methylated lysine80 def: "Protein H31T_HUMAN with the residue 80 substituted with N6-methylated lysine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066743 name: H31T_HUMAN-N6-methylated lysine123 def: "Protein H31T_HUMAN with the residue 123 substituted with N6-methylated lysine" [UniProtKB:Q16695] comment: By similarity xref: UniProtKB:Q16695 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:B0066744 name: HABP4_HUMAN-Phosphoserine97 def: "Protein HABP4_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q5JVS0] xref: UniProtKB:Q5JVS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037756 ! HABP4_HUMAN [Term] id: CCO:B0066745 name: HABP4_HUMAN-Phosphoserine108 def: "Protein HABP4_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q5JVS0] xref: UniProtKB:Q5JVS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0037756 ! HABP4_HUMAN [Term] id: CCO:B0066746 name: HAP28_HUMAN-Phosphoserine19 def: "Protein HAP28_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q13442] xref: UniProtKB:Q13442 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055908 ! HAP28_HUMAN [Term] id: CCO:B0066747 name: HAP28_HUMAN-Phosphoserine57 def: "Protein HAP28_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:Q13442] xref: UniProtKB:Q13442 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055908 ! HAP28_HUMAN [Term] id: CCO:B0066748 name: HAP28_HUMAN-Phosphoserine60 def: "Protein HAP28_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q13442] xref: UniProtKB:Q13442 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055908 ! HAP28_HUMAN [Term] id: CCO:B0066749 name: HAP28_HUMAN-Phosphoserine63 def: "Protein HAP28_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:Q13442] xref: UniProtKB:Q13442 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055908 ! HAP28_HUMAN [Term] id: CCO:B0066750 name: HAP28_HUMAN-Phosphotyrosine70 def: "Protein HAP28_HUMAN with the residue 70 substituted with Phosphotyrosine" [UniProtKB:Q13442] xref: UniProtKB:Q13442 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055908 ! HAP28_HUMAN [Term] id: CCO:B0066751 name: HAP28_HUMAN-Phosphoserine176 def: "Protein HAP28_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q13442] xref: UniProtKB:Q13442 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055908 ! HAP28_HUMAN [Term] id: CCO:B0066752 name: HASP_HUMAN-Phosphoserine93 def: "Protein HASP_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q8TF76] xref: UniProtKB:Q8TF76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001999 ! HASP_HUMAN [Term] id: CCO:B0066753 name: HASP_HUMAN-Phosphothreonine97 def: "Protein HASP_HUMAN with the residue 97 substituted with Phosphothreonine" [UniProtKB:Q8TF76] xref: UniProtKB:Q8TF76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001999 ! HASP_HUMAN [Term] id: CCO:B0066754 name: HASP_HUMAN-Phosphoserine143 def: "Protein HASP_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q8TF76] xref: UniProtKB:Q8TF76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001999 ! HASP_HUMAN [Term] id: CCO:B0066755 name: HASP_HUMAN-Phosphoserine147 def: "Protein HASP_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:Q8TF76] xref: UniProtKB:Q8TF76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001999 ! HASP_HUMAN [Term] id: CCO:B0066756 name: HAX1_HUMAN-N-acetylserine2 def: "Protein HAX1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:O00165] xref: UniProtKB:O00165 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004231 ! interleukin-1 binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0062934 ! HAX1_HUMAN [Term] id: CCO:B0066757 name: HBAZ_HUMAN-N-acetylserine2 def: "Protein HBAZ_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P02008] xref: UniProtKB:P02008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001572 ! oxygen transporter activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0004183 ! oxygen binding relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000401 ! hemoglobin complex relationship: transformation_of CCO:B0063458 ! HBAZ_HUMAN [Term] id: CCO:B0066758 name: HBA_HUMAN-Phosphotyrosine25 def: "Protein HBA_HUMAN with the residue 25 substituted with Phosphotyrosine" [UniProtKB:P69905] xref: UniProtKB:P69905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001572 ! oxygen transporter activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004183 ! oxygen binding relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000401 ! hemoglobin complex relationship: transformation_of CCO:B0006221 ! HBA_HUMAN [Term] id: CCO:B0066759 name: HBA_HUMAN-Phosphotyrosine43 def: "Protein HBA_HUMAN with the residue 43 substituted with Phosphotyrosine" [UniProtKB:P69905] xref: UniProtKB:P69905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006221 ! HBA_HUMAN [Term] id: CCO:B0066760 name: HBB_HUMAN-N-acetylalanine2 def: "Protein HBB_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P68871] comment: in variant Raleigh; xref: UniProtKB:P68871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:B0066761 name: HBB_HUMAN-2-iminyl-valine2 def: "Protein HBB_HUMAN with the residue 2 substituted with 2-iminyl-valine" [UniProtKB:P68871] comment: in Hb A1b; xref: UniProtKB:P68871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:B0066762 name: HBB_HUMAN-S-nitrosocysteine94 def: "Protein HBB_HUMAN with the residue 94 substituted with S-nitrosocysteine" [UniProtKB:P68871] xref: UniProtKB:P68871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:B0066763 name: HBB_HUMAN-Phosphotyrosine131 def: "Protein HBB_HUMAN with the residue 131 substituted with Phosphotyrosine" [UniProtKB:P68871] xref: UniProtKB:P68871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001572 ! oxygen transporter activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004183 ! oxygen binding relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0004445 ! hemoglobin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000401 ! hemoglobin complex relationship: transformation_of CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:B0066764 name: HCC1_HUMAN-N-acetylalanine2 def: "Protein HCC1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P82979] xref: UniProtKB:P82979 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055658 ! HCC1_HUMAN [Term] id: CCO:B0066765 name: HCC1_HUMAN-Phosphoserine163 def: "Protein HCC1_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:P82979] xref: UniProtKB:P82979 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055658 ! HCC1_HUMAN [Term] id: CCO:B0066766 name: HCD2_HUMAN-N-acetylalanine2 def: "Protein HCD2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q99714] comment: By similarity xref: UniProtKB:Q99714 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063213 ! HCD2_HUMAN [Term] id: CCO:B0066767 name: HCFC1_HUMAN-Phosphoserine1205 def: "Protein HCFC1_HUMAN with the residue 1205 substituted with Phosphoserine" [UniProtKB:P51610] xref: UniProtKB:P51610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:B0066768 name: HCK_HUMAN-Phosphotyrosine209 def: "Protein HCK_HUMAN with the residue 209 substituted with Phosphotyrosine" [UniProtKB:P08631] xref: UniProtKB:P08631 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:B0066769 name: HCLS1_HUMAN-Phosphotyrosine103 def: "Protein HCLS1_HUMAN with the residue 103 substituted with Phosphotyrosine" [UniProtKB:P14317] xref: UniProtKB:P14317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055023 ! HCLS1_HUMAN [Term] id: CCO:B0066770 name: HCLS1_HUMAN-Phosphotyrosine140 def: "Protein HCLS1_HUMAN with the residue 140 substituted with Phosphotyrosine" [UniProtKB:P14317] comment: By similarity xref: UniProtKB:P14317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055023 ! HCLS1_HUMAN [Term] id: CCO:B0066771 name: HCLS1_HUMAN-Phosphotyrosine198 def: "Protein HCLS1_HUMAN with the residue 198 substituted with Phosphotyrosine" [UniProtKB:P14317] xref: UniProtKB:P14317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055023 ! HCLS1_HUMAN [Term] id: CCO:B0066772 name: HCLS1_HUMAN-Phosphotyrosine222 def: "Protein HCLS1_HUMAN with the residue 222 substituted with Phosphotyrosine" [UniProtKB:P14317] xref: UniProtKB:P14317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055023 ! HCLS1_HUMAN [Term] id: CCO:B0066773 name: HCLS1_HUMAN-Phosphoserine275 def: "Protein HCLS1_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:P14317] xref: UniProtKB:P14317 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055023 ! HCLS1_HUMAN [Term] id: CCO:B0066774 name: HDAC4_HUMAN-Phosphoserine565 def: "Protein HDAC4_HUMAN with the residue 565 substituted with Phosphoserine" [UniProtKB:P56524] xref: UniProtKB:P56524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001679 ! HDAC4_HUMAN [Term] id: CCO:B0066775 name: HDAC4_HUMAN-Phosphoserine633 def: "Protein HDAC4_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:P56524] xref: UniProtKB:P56524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001679 ! HDAC4_HUMAN [Term] id: CCO:B0066776 name: HDAC7_HUMAN-Phosphoserine109 def: "Protein HDAC7_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q8WUI4] xref: UniProtKB:Q8WUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002002 ! HDAC7_HUMAN [Term] id: CCO:B0066777 name: HDAC7_HUMAN-Phosphoserine283 def: "Protein HDAC7_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q8WUI4] xref: UniProtKB:Q8WUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002002 ! HDAC7_HUMAN [Term] id: CCO:B0066778 name: HDAC7_HUMAN-Phosphothreonine286 def: "Protein HDAC7_HUMAN with the residue 286 substituted with Phosphothreonine" [UniProtKB:Q8WUI4] xref: UniProtKB:Q8WUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002002 ! HDAC7_HUMAN [Term] id: CCO:B0066779 name: HDAC7_HUMAN-Phosphoserine486 def: "Protein HDAC7_HUMAN with the residue 486 substituted with Phosphoserine" [UniProtKB:Q8WUI4] xref: UniProtKB:Q8WUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002002 ! HDAC7_HUMAN [Term] id: CCO:B0066780 name: HDGF_HUMAN-Phosphoserine107 def: "Protein HDGF_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066781 name: HDGF_HUMAN-Phosphoserine132 def: "Protein HDGF_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066782 name: HDGF_HUMAN-Phosphoserine133 def: "Protein HDGF_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066783 name: HDGF_HUMAN-Phosphoserine165 def: "Protein HDGF_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066784 name: HDGF_HUMAN-Phosphoserine199 def: "Protein HDGF_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:P51858] comment: By similarity xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066785 name: HDGF_HUMAN-Phosphothreonine200 def: "Protein HDGF_HUMAN with the residue 200 substituted with Phosphothreonine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066786 name: HDGF_HUMAN-Phosphoserine202 def: "Protein HDGF_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066787 name: HDGF_HUMAN-Phosphoserine206 def: "Protein HDGF_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066788 name: HDGF_HUMAN-Phosphoserine239 def: "Protein HDGF_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:P51858] xref: UniProtKB:P51858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055484 ! HDGF_HUMAN [Term] id: CCO:B0066789 name: HD_HUMAN-Phosphoserine413 def: "Protein HD_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:P42858] xref: UniProtKB:P42858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005407 ! HD_HUMAN [Term] id: CCO:B0066790 name: HD_HUMAN-Phosphoserine1872 def: "Protein HD_HUMAN with the residue 1872 substituted with Phosphoserine" [UniProtKB:P42858] xref: UniProtKB:P42858 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005407 ! HD_HUMAN [Term] id: CCO:B0066791 name: HELB_HUMAN-Phosphoserine708 def: "Protein HELB_HUMAN with the residue 708 substituted with Phosphoserine" [UniProtKB:Q8NG08] xref: UniProtKB:Q8NG08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057611 ! HELB_HUMAN [Term] id: CCO:B0066792 name: HELB_HUMAN-Phosphoserine709 def: "Protein HELB_HUMAN with the residue 709 substituted with Phosphoserine" [UniProtKB:Q8NG08] xref: UniProtKB:Q8NG08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003578 ! single-stranded DNA-dependent ATP-dependent DNA helicase activity relationship: has_function CCO:F0005803 ! ATP-dependent 5'-3' DNA helicase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000266 ! alpha DNA polymerase:primase complex relationship: transformation_of CCO:B0057611 ! HELB_HUMAN [Term] id: CCO:B0066793 name: HELB_HUMAN-Phosphoserine967 def: "Protein HELB_HUMAN with the residue 967 substituted with Phosphoserine" [UniProtKB:Q8NG08] xref: UniProtKB:Q8NG08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057611 ! HELB_HUMAN [Term] id: CCO:B0066794 name: HELB_HUMAN-Phosphoserine971 def: "Protein HELB_HUMAN with the residue 971 substituted with Phosphoserine" [UniProtKB:Q8NG08] comment: By similarity xref: UniProtKB:Q8NG08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057611 ! HELB_HUMAN [Term] id: CCO:B0066795 name: HELB_HUMAN-Phosphoserine1021 def: "Protein HELB_HUMAN with the residue 1021 substituted with Phosphoserine" [UniProtKB:Q8NG08] xref: UniProtKB:Q8NG08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057611 ! HELB_HUMAN [Term] id: CCO:B0066796 name: HELB_HUMAN-Phosphoserine1048 def: "Protein HELB_HUMAN with the residue 1048 substituted with Phosphoserine" [UniProtKB:Q8NG08] xref: UniProtKB:Q8NG08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057611 ! HELB_HUMAN [Term] id: CCO:B0066797 name: HES7_HUMAN-Phosphoserine170 def: "Protein HES7_HUMAN with the residue 170 substituted with Phosphoserine" [UniProtKB:Q9BYE0] xref: UniProtKB:Q9BYE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058576 ! HES7_HUMAN [Term] id: CCO:B0066798 name: HEXI2_HUMAN-Phosphoserine29 def: "Protein HEXI2_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q96MH2] xref: UniProtKB:Q96MH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002049 ! HEXI2_HUMAN [Term] id: CCO:B0066799 name: HEXI2_HUMAN-Phosphothreonine32 def: "Protein HEXI2_HUMAN with the residue 32 substituted with Phosphothreonine" [UniProtKB:Q96MH2] xref: UniProtKB:Q96MH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001217 ! cyclin-dependent protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003544 ! snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002049 ! HEXI2_HUMAN [Term] id: CCO:B0066800 name: HEXI2_HUMAN-Phosphoserine76 def: "Protein HEXI2_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q96MH2] xref: UniProtKB:Q96MH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002049 ! HEXI2_HUMAN [Term] id: CCO:B0066801 name: HEXI2_HUMAN-Phosphoserine81 def: "Protein HEXI2_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:Q96MH2] xref: UniProtKB:Q96MH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002049 ! HEXI2_HUMAN [Term] id: CCO:B0066802 name: HGS_HUMAN-Phosphotyrosine132 def: "Protein HGS_HUMAN with the residue 132 substituted with Phosphotyrosine" [UniProtKB:O14964] xref: UniProtKB:O14964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:B0066803 name: HINT1_HUMAN-N-acetylalanine2 def: "Protein HINT1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P49773] comment: By similarity xref: UniProtKB:P49773 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055436 ! HINT1_HUMAN [Term] id: CCO:B0066804 name: HIPK2_HUMAN-Phosphotyrosine361 def: "Protein HIPK2_HUMAN with the residue 361 substituted with Phosphotyrosine" [UniProtKB:Q9H2X6] xref: UniProtKB:Q9H2X6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006246 ! virion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000817 ! nuclear body relationship: transformation_of CCO:B0002130 ! HIPK2_HUMAN [Term] id: CCO:B0066805 name: HIPK3_HUMAN-Phosphotyrosine359 def: "Protein HIPK3_HUMAN with the residue 359 substituted with Phosphotyrosine" [UniProtKB:Q9H422] xref: UniProtKB:Q9H422 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0015655 ! HIPK3_HUMAN [Term] id: CCO:B0066806 name: HIRA_HUMAN-Phosphothreonine576 def: "Protein HIRA_HUMAN with the residue 576 substituted with Phosphothreonine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0066807 name: HIRA_HUMAN-Phosphoserine584 def: "Protein HIRA_HUMAN with the residue 584 substituted with Phosphoserine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0066808 name: HIRA_HUMAN-Phosphothreonine586 def: "Protein HIRA_HUMAN with the residue 586 substituted with Phosphothreonine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0066809 name: HIRA_HUMAN-Phosphoserine610 def: "Protein HIRA_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0066810 name: HIRA_HUMAN-Phosphoserine611 def: "Protein HIRA_HUMAN with the residue 611 substituted with Phosphoserine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0066811 name: HIRA_HUMAN-Phosphoserine612 def: "Protein HIRA_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0066812 name: HIRA_HUMAN-Phosphoserine614 def: "Protein HIRA_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:P54198] xref: UniProtKB:P54198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016028 ! HIRA_HUMAN [Term] id: CCO:B0066813 name: HLTF_HUMAN-Phosphothreonine390 def: "Protein HLTF_HUMAN with the residue 390 substituted with Phosphothreonine" [UniProtKB:Q14527] xref: UniProtKB:Q14527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055989 ! HLTF_HUMAN [Term] id: CCO:B0066814 name: HLTF_HUMAN-Phosphotyrosine394 def: "Protein HLTF_HUMAN with the residue 394 substituted with Phosphotyrosine" [UniProtKB:Q14527] xref: UniProtKB:Q14527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055989 ! HLTF_HUMAN [Term] id: CCO:B0066815 name: HLTF_HUMAN-Phosphoserine397 def: "Protein HLTF_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q14527] xref: UniProtKB:Q14527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055989 ! HLTF_HUMAN [Term] id: CCO:B0066816 name: HLTF_HUMAN-Phosphoserine398 def: "Protein HLTF_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:Q14527] xref: UniProtKB:Q14527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055989 ! HLTF_HUMAN [Term] id: CCO:B0066817 name: HLTF_HUMAN-Phosphoserine400 def: "Protein HLTF_HUMAN with the residue 400 substituted with Phosphoserine" [UniProtKB:Q14527] xref: UniProtKB:Q14527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055989 ! HLTF_HUMAN [Term] id: CCO:B0066818 name: HLTF_HUMAN-Phosphoserine635 def: "Protein HLTF_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:Q14527] comment: By similarity xref: UniProtKB:Q14527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055989 ! HLTF_HUMAN [Term] id: CCO:B0066819 name: HLTF_HUMAN-Phosphothreonine736 def: "Protein HLTF_HUMAN with the residue 736 substituted with Phosphothreonine" [UniProtKB:Q14527] xref: UniProtKB:Q14527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055989 ! HLTF_HUMAN [Term] id: CCO:B0066820 name: HM20A_HUMAN-Phosphoserine105 def: "Protein HM20A_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q9NP66] xref: UniProtKB:Q9NP66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005296 ! HM20A_HUMAN [Term] id: CCO:B0066821 name: HMGA1_HUMAN-N-acetylserine2 def: "Protein HMGA1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P17096] comment: By similarity xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066822 name: HMGA1_HUMAN-dimethylarginine26 def: "Protein HMGA1_HUMAN with the residue 26 substituted with dimethylarginine" [UniProtKB:P17096] comment: in isoform HMG-I; alternate; xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066823 name: HMGA1_HUMAN-Omega-N-methylarginine26 def: "Protein HMGA1_HUMAN with the residue 26 substituted with Omega-N-methylarginine" [UniProtKB:P17096] comment: in isoform HMG-I; alternate; xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066824 name: HMGA1_HUMAN-Phosphoserine36 def: "Protein HMGA1_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P17096] xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000276 ! AT DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005774 ! retinoic acid receptor binding relationship: has_function CCO:F0005775 ! peroxisome proliferator activated receptor binding relationship: has_function CCO:F0006286 ! retinoid X receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066825 name: HMGA1_HUMAN-Phosphoserine44 def: "Protein HMGA1_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:P17096] xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066826 name: HMGA1_HUMAN-Phosphoserine49 def: "Protein HMGA1_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:P17096] comment: By similarity xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066827 name: HMGA1_HUMAN-Phosphothreonine53 def: "Protein HMGA1_HUMAN with the residue 53 substituted with Phosphothreonine" [UniProtKB:P17096] xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066828 name: HMGA1_HUMAN-Phosphoserine99 def: "Protein HMGA1_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:P17096] comment: in isoform HMG-I and isoform HMG-Y; xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066829 name: HMGA1_HUMAN-Phosphoserine102 def: "Protein HMGA1_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:P17096] comment: by CK; in isoform HMG-I and isoform HMG-Y; xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066830 name: HMGA1_HUMAN-Phosphoserine103 def: "Protein HMGA1_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:P17096] comment: by CK; in isoform HMG-I and isoform HMG-Y; xref: UniProtKB:P17096 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:B0066831 name: HMGCL_HUMAN-N6-acetyllysine48 def: "Protein HMGCL_HUMAN with the residue 48 substituted with N6-acetyllysine" [UniProtKB:P35914] comment: By similarity xref: UniProtKB:P35914 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000828 ! hydroxymethylglutaryl-CoA lyase activity relationship: has_function CCO:F0003396 ! lyase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: transformation_of CCO:B0063475 ! HMGCL_HUMAN [Term] id: CCO:B0066832 name: HMGN2_HUMAN-Phosphoserine25 def: "Protein HMGN2_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:P05204] xref: UniProtKB:P05204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054898 ! HMGN2_HUMAN [Term] id: CCO:B0066833 name: HMGN2_HUMAN-Phosphoserine29 def: "Protein HMGN2_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:P05204] xref: UniProtKB:P05204 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054898 ! HMGN2_HUMAN [Term] id: CCO:B0066834 name: HMHA1_HUMAN-Phosphoserine23 def: "Protein HMHA1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q92619] xref: UniProtKB:Q92619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058075 ! HMHA1_HUMAN [Term] id: CCO:B0066835 name: HMHA1_HUMAN-Phosphoserine25 def: "Protein HMHA1_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q92619] xref: UniProtKB:Q92619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058075 ! HMHA1_HUMAN [Term] id: CCO:B0066836 name: HMHA1_HUMAN-Phosphoserine1027 def: "Protein HMHA1_HUMAN with the residue 1027 substituted with Phosphoserine" [UniProtKB:Q92619] comment: By similarity xref: UniProtKB:Q92619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058075 ! HMHA1_HUMAN [Term] id: CCO:B0066837 name: HMHA1_HUMAN-Phosphoserine1030 def: "Protein HMHA1_HUMAN with the residue 1030 substituted with Phosphoserine" [UniProtKB:Q92619] comment: By similarity xref: UniProtKB:Q92619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058075 ! HMHA1_HUMAN [Term] id: CCO:B0066838 name: HMHA1_HUMAN-Phosphoserine1032 def: "Protein HMHA1_HUMAN with the residue 1032 substituted with Phosphoserine" [UniProtKB:Q92619] comment: By similarity xref: UniProtKB:Q92619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058075 ! HMHA1_HUMAN [Term] id: CCO:B0066839 name: HMOX1_HUMAN-Phosphoserine229 def: "Protein HMOX1_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:P09601] xref: UniProtKB:P09601 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000804 ! heme oxygenase (decyclizing) activity relationship: has_function CCO:F0001004 ! phospholipase D activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0054947 ! HMOX1_HUMAN [Term] id: CCO:B0066840 name: HN1L_HUMAN-Phosphoserine25 def: "Protein HN1L_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066841 name: HN1L_HUMAN-Phosphoserine30 def: "Protein HN1L_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066842 name: HN1L_HUMAN-Phosphothreonine35 def: "Protein HN1L_HUMAN with the residue 35 substituted with Phosphothreonine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066843 name: HN1L_HUMAN-Phosphoserine75 def: "Protein HN1L_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066844 name: HN1L_HUMAN-Phosphothreonine76 def: "Protein HN1L_HUMAN with the residue 76 substituted with Phosphothreonine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066845 name: HN1L_HUMAN-Phosphoserine97 def: "Protein HN1L_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066846 name: HN1L_HUMAN-Phosphoserine125 def: "Protein HN1L_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066847 name: HN1L_HUMAN-Phosphoserine132 def: "Protein HN1L_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066848 name: HN1L_HUMAN-Phosphoserine144 def: "Protein HN1L_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q9H910] xref: UniProtKB:Q9H910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:B0066849 name: HNF1A_HUMAN-Phosphoserine247 def: "Protein HNF1A_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:P20823] comment: By similarity xref: UniProtKB:P20823 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006008 ! HNF1A_HUMAN [Term] id: CCO:B0066850 name: HNF1B_HUMAN-Phosphoserine75 def: "Protein HNF1B_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:P35680] comment: By similarity xref: UniProtKB:P35680 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055299 ! HNF1B_HUMAN [Term] id: CCO:B0066851 name: HNF1B_HUMAN-Phosphoserine80 def: "Protein HNF1B_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:P35680] comment: By similarity xref: UniProtKB:P35680 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055299 ! HNF1B_HUMAN [Term] id: CCO:B0066852 name: HNRDL_HUMAN-Phosphoserine241 def: "Protein HNRDL_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:O14979] xref: UniProtKB:O14979 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054395 ! HNRDL_HUMAN [Term] id: CCO:B0066853 name: HNRDL_HUMAN-Omega-N-methylated arginine408 def: "Protein HNRDL_HUMAN with the residue 408 substituted with Omega-N-methylated arginine" [UniProtKB:O14979] xref: UniProtKB:O14979 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054395 ! HNRDL_HUMAN [Term] id: CCO:B0066854 name: HNRH1_HUMAN-Phosphothreonine107 def: "Protein HNRH1_HUMAN with the residue 107 substituted with Phosphothreonine" [UniProtKB:P31943] xref: UniProtKB:P31943 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001806 ! poly(U) binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:B0066855 name: HNRH2_HUMAN-Phosphoserine104 def: "Protein HNRH2_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:P55795] xref: UniProtKB:P55795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063355 ! HNRH2_HUMAN [Term] id: CCO:B0066856 name: HNRH2_HUMAN-Phosphothreonine107 def: "Protein HNRH2_HUMAN with the residue 107 substituted with Phosphothreonine" [UniProtKB:P55795] xref: UniProtKB:P55795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0063355 ! HNRH2_HUMAN [Term] id: CCO:B0066857 name: HNRH2_HUMAN-Asymmetric dimethylarginine217 def: "Protein HNRH2_HUMAN with the residue 217 substituted with Asymmetric dimethylarginine" [UniProtKB:P55795] comment: By similarity xref: UniProtKB:P55795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063355 ! HNRH2_HUMAN [Term] id: CCO:B0066858 name: HNRH2_HUMAN-Phosphoserine310 def: "Protein HNRH2_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:P55795] xref: UniProtKB:P55795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063355 ! HNRH2_HUMAN [Term] id: CCO:B0066859 name: HNRL1_HUMAN-Phosphoserine194 def: "Protein HNRL1_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q9BUJ2] xref: UniProtKB:Q9BUJ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058522 ! HNRL1_HUMAN [Term] id: CCO:B0066860 name: HNRL1_HUMAN-Phosphoserine512 def: "Protein HNRL1_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q9BUJ2] xref: UniProtKB:Q9BUJ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0058522 ! HNRL1_HUMAN [Term] id: CCO:B0066861 name: HNRL1_HUMAN-Phosphoserine718 def: "Protein HNRL1_HUMAN with the residue 718 substituted with Phosphoserine" [UniProtKB:Q9BUJ2] xref: UniProtKB:Q9BUJ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058522 ! HNRL1_HUMAN [Term] id: CCO:B0066862 name: HNRPC_HUMAN-Phosphoserine120 def: "Protein HNRPC_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0066863 name: HNRPC_HUMAN-Phosphoserine121 def: "Protein HNRPC_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:P07910] xref: UniProtKB:P07910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:B0066864 name: HNRPF_HUMAN-N-acetylmethionine1 def: "Protein HNRPF_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P52597] comment: alternate; xref: UniProtKB:P52597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005814 ! HNRPF_HUMAN [Term] id: CCO:B0066865 name: HNRPG_HUMAN-Phosphoserine326 def: "Protein HNRPG_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0066866 name: HNRPG_HUMAN-Phosphotyrosine327 def: "Protein HNRPG_HUMAN with the residue 327 substituted with Phosphotyrosine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0066867 name: HNRPG_HUMAN-Phosphoserine329 def: "Protein HNRPG_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:P38159] xref: UniProtKB:P38159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:B0066868 name: HNRPM_HUMAN-N-acetylalanine2 def: "Protein HNRPM_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066869 name: HNRPM_HUMAN-Phosphoserine432 def: "Protein HNRPM_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066870 name: HNRPM_HUMAN-Phosphoserine468 def: "Protein HNRPM_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066871 name: HNRPM_HUMAN-Phosphoserine513 def: "Protein HNRPM_HUMAN with the residue 513 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066872 name: HNRPM_HUMAN-Phosphoserine528 def: "Protein HNRPM_HUMAN with the residue 528 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066873 name: HNRPM_HUMAN-Phosphoserine588 def: "Protein HNRPM_HUMAN with the residue 588 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066874 name: HNRPM_HUMAN-Phosphoserine618 def: "Protein HNRPM_HUMAN with the residue 618 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066875 name: HNRPM_HUMAN-Phosphoserine633 def: "Protein HNRPM_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066876 name: HNRPM_HUMAN-Phosphoserine637 def: "Protein HNRPM_HUMAN with the residue 637 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066877 name: HNRPM_HUMAN-Phosphoserine701 def: "Protein HNRPM_HUMAN with the residue 701 substituted with Phosphoserine" [UniProtKB:P52272] xref: UniProtKB:P52272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:B0066878 name: HNRPU_HUMAN-N-acetylserine2 def: "Protein HNRPU_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066879 name: HNRPU_HUMAN-Phosphoserine4 def: "Protein HNRPU_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066880 name: HNRPU_HUMAN-Phosphoserine26 def: "Protein HNRPU_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066881 name: HNRPU_HUMAN-Omega-N-methylarginine50 def: "Protein HNRPU_HUMAN with the residue 50 substituted with Omega-N-methylarginine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066882 name: HNRPU_HUMAN-Phosphoserine59 def: "Protein HNRPU_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066883 name: HNRPU_HUMAN-Phosphoserine66 def: "Protein HNRPU_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066884 name: HNRPU_HUMAN-Phosphoserine188 def: "Protein HNRPU_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066885 name: HNRPU_HUMAN-Phosphoserine270 def: "Protein HNRPU_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066886 name: HNRPU_HUMAN-Phosphotyrosine472 def: "Protein HNRPU_HUMAN with the residue 472 substituted with Phosphotyrosine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066887 name: HNRPU_HUMAN-Omega-N-methylated arginine732 def: "Protein HNRPU_HUMAN with the residue 732 substituted with Omega-N-methylated arginine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001020 ! heterogeneous nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066888 name: HNRPU_HUMAN-Omega-N-methylated arginine738 def: "Protein HNRPU_HUMAN with the residue 738 substituted with Omega-N-methylated arginine" [UniProtKB:Q00839] xref: UniProtKB:Q00839 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:B0066889 name: HOME3_HUMAN-Phosphoserine159 def: "Protein HOME3_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:Q9NSC5] xref: UniProtKB:Q9NSC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0058915 ! HOME3_HUMAN [Term] id: CCO:B0066890 name: HOMEZ_HUMAN-Phosphothreonine427 def: "Protein HOMEZ_HUMAN with the residue 427 substituted with Phosphothreonine" [UniProtKB:Q8IX15] xref: UniProtKB:Q8IX15 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057368 ! HOMEZ_HUMAN [Term] id: CCO:B0066891 name: HOOK2_HUMAN-Phosphoserine163 def: "Protein HOOK2_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:Q96ED9] xref: UniProtKB:Q96ED9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062809 ! HOOK2_HUMAN [Term] id: CCO:B0066892 name: HPBP1_HUMAN-Phosphoserine354 def: "Protein HPBP1_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q9NZL4] xref: UniProtKB:Q9NZL4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005199 ! HPBP1_HUMAN [Term] id: CCO:B0066893 name: HPBP1_HUMAN-Phosphoserine359 def: "Protein HPBP1_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:Q9NZL4] xref: UniProtKB:Q9NZL4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005199 ! HPBP1_HUMAN [Term] id: CCO:B0066894 name: HPS4_HUMAN-Phosphoserine355 def: "Protein HPS4_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q9NQG7] xref: UniProtKB:Q9NQG7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0001705 ! platelet dense granule relationship: transformation_of CCO:B0058867 ! HPS4_HUMAN [Term] id: CCO:B0066895 name: HRH1_HUMAN-Phosphoserine275 def: "Protein HRH1_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:P35367] xref: UniProtKB:P35367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001310 ! histamine receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055287 ! HRH1_HUMAN [Term] id: CCO:B0066896 name: HRH1_HUMAN-Phosphothreonine279 def: "Protein HRH1_HUMAN with the residue 279 substituted with Phosphothreonine" [UniProtKB:P35367] xref: UniProtKB:P35367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055287 ! HRH1_HUMAN [Term] id: CCO:B0066897 name: HRX_HUMAN-Phosphoserine136 def: "Protein HRX_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066898 name: HRX_HUMAN-Phosphoserine153 def: "Protein HRX_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066899 name: HRX_HUMAN-Phosphoserine197 def: "Protein HRX_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066900 name: HRX_HUMAN-Phosphoserine202 def: "Protein HRX_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066901 name: HRX_HUMAN-Phosphothreonine506 def: "Protein HRX_HUMAN with the residue 506 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066902 name: HRX_HUMAN-Phosphoserine680 def: "Protein HRX_HUMAN with the residue 680 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066903 name: HRX_HUMAN-Phosphoserine831 def: "Protein HRX_HUMAN with the residue 831 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066904 name: HRX_HUMAN-Phosphothreonine840 def: "Protein HRX_HUMAN with the residue 840 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066905 name: HRX_HUMAN-Phosphoserine1056 def: "Protein HRX_HUMAN with the residue 1056 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066906 name: HRX_HUMAN-Phosphothreonine1839 def: "Protein HRX_HUMAN with the residue 1839 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066907 name: HRX_HUMAN-Phosphoserine2098 def: "Protein HRX_HUMAN with the residue 2098 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066908 name: HRX_HUMAN-Phosphothreonine2147 def: "Protein HRX_HUMAN with the residue 2147 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066909 name: HRX_HUMAN-Phosphothreonine2525 def: "Protein HRX_HUMAN with the residue 2525 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066910 name: HRX_HUMAN-Phosphoserine2955 def: "Protein HRX_HUMAN with the residue 2955 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066911 name: HRX_HUMAN-Phosphothreonine3372 def: "Protein HRX_HUMAN with the residue 3372 substituted with Phosphothreonine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066912 name: HRX_HUMAN-Phosphoserine3518 def: "Protein HRX_HUMAN with the residue 3518 substituted with Phosphoserine" [UniProtKB:Q03164] xref: UniProtKB:Q03164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:B0066913 name: HS105_HUMAN-Phosphoserine31 def: "Protein HS105_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q92598] xref: UniProtKB:Q92598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:B0066914 name: HS105_HUMAN-Phosphoserine384 def: "Protein HS105_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q92598] xref: UniProtKB:Q92598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:B0066915 name: HS105_HUMAN-Phosphoserine509 def: "Protein HS105_HUMAN with the residue 509 substituted with Phosphoserine" [UniProtKB:Q92598] comment: By similarity xref: UniProtKB:Q92598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:B0066916 name: HS105_HUMAN-Phosphoserine557 def: "Protein HS105_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:Q92598] xref: UniProtKB:Q92598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:B0066917 name: HS105_HUMAN-Phosphothreonine700 def: "Protein HS105_HUMAN with the residue 700 substituted with Phosphothreonine" [UniProtKB:Q92598] xref: UniProtKB:Q92598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:B0066918 name: HS105_HUMAN-Phosphoserine809 def: "Protein HS105_HUMAN with the residue 809 substituted with Phosphoserine" [UniProtKB:Q92598] xref: UniProtKB:Q92598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:B0066919 name: HS105_HUMAN-Phosphothreonine815 def: "Protein HS105_HUMAN with the residue 815 substituted with Phosphothreonine" [UniProtKB:Q92598] xref: UniProtKB:Q92598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:B0066920 name: HS12A_HUMAN-Phosphoserine23 def: "Protein HS12A_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:O43301] comment: By similarity xref: UniProtKB:O43301 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063147 ! HS12A_HUMAN [Term] id: CCO:B0066921 name: HS74L_HUMAN-Phosphoserine74 def: "Protein HS74L_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:O95757] comment: By similarity xref: UniProtKB:O95757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063129 ! HS74L_HUMAN [Term] id: CCO:B0066922 name: HS74L_HUMAN-Phosphothreonine761 def: "Protein HS74L_HUMAN with the residue 761 substituted with Phosphothreonine" [UniProtKB:O95757] xref: UniProtKB:O95757 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063129 ! HS74L_HUMAN [Term] id: CCO:B0066923 name: HSF1_HUMAN-Phosphothreonine369 def: "Protein HSF1_HUMAN with the residue 369 substituted with Phosphothreonine" [UniProtKB:Q00613] xref: UniProtKB:Q00613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:B0066924 name: HSP71_HUMAN-Phosphotyrosine41 def: "Protein HSP71_HUMAN with the residue 41 substituted with Phosphotyrosine" [UniProtKB:P08107] xref: UniProtKB:P08107 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005822 ! HSP71_HUMAN [Term] id: CCO:B0066925 name: HSP72_HUMAN-Phosphotyrosine42 def: "Protein HSP72_HUMAN with the residue 42 substituted with Phosphotyrosine" [UniProtKB:P54652] xref: UniProtKB:P54652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001670 ! HSP72_HUMAN [Term] id: CCO:B0066926 name: HSP72_HUMAN-Phosphotyrosine108 def: "Protein HSP72_HUMAN with the residue 108 substituted with Phosphotyrosine" [UniProtKB:P54652] xref: UniProtKB:P54652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000709 ! cell surface relationship: transformation_of CCO:B0001670 ! HSP72_HUMAN [Term] id: CCO:B0066927 name: HSP74_HUMAN-Phosphoserine76 def: "Protein HSP74_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:P34932] xref: UniProtKB:P34932 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:B0066928 name: HSP74_HUMAN-Phosphotyrosine89 def: "Protein HSP74_HUMAN with the residue 89 substituted with Phosphotyrosine" [UniProtKB:P34932] xref: UniProtKB:P34932 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:B0066929 name: HSP74_HUMAN-Phosphotyrosine336 def: "Protein HSP74_HUMAN with the residue 336 substituted with Phosphotyrosine" [UniProtKB:P34932] xref: UniProtKB:P34932 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:B0066930 name: HSP74_HUMAN-Phosphothreonine538 def: "Protein HSP74_HUMAN with the residue 538 substituted with Phosphothreonine" [UniProtKB:P34932] xref: UniProtKB:P34932 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:B0066931 name: HSP74_HUMAN-Phosphoserine552 def: "Protein HSP74_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:P34932] xref: UniProtKB:P34932 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:B0066932 name: HSP74_HUMAN-Phosphotyrosine660 def: "Protein HSP74_HUMAN with the residue 660 substituted with Phosphotyrosine" [UniProtKB:P34932] comment: By similarity xref: UniProtKB:P34932 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:B0066933 name: HSP7C_HUMAN-Phosphotyrosine107 def: "Protein HSP7C_HUMAN with the residue 107 substituted with Phosphotyrosine" [UniProtKB:P11142] xref: UniProtKB:P11142 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:B0066934 name: HSPB8_HUMAN-Phosphoserine24 def: "Protein HSPB8_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q9UJY1] xref: UniProtKB:Q9UJY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0024107 ! HSPB8_HUMAN [Term] id: CCO:B0066935 name: HSPB8_HUMAN-Phosphotyrosine118 def: "Protein HSPB8_HUMAN with the residue 118 substituted with Phosphotyrosine" [UniProtKB:Q9UJY1] xref: UniProtKB:Q9UJY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024107 ! HSPB8_HUMAN [Term] id: CCO:B0066936 name: HTF4_HUMAN-Phosphoserine44 def: "Protein HTF4_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q99081] xref: UniProtKB:Q99081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058408 ! HTF4_HUMAN [Term] id: CCO:B0066937 name: HTF4_HUMAN-Phosphoserine47 def: "Protein HTF4_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q99081] xref: UniProtKB:Q99081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058408 ! HTF4_HUMAN [Term] id: CCO:B0066938 name: HTF4_HUMAN-Phosphoserine305 def: "Protein HTF4_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q99081] xref: UniProtKB:Q99081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058408 ! HTF4_HUMAN [Term] id: CCO:B0066939 name: HTF4_HUMAN-Phosphothreonine313 def: "Protein HTF4_HUMAN with the residue 313 substituted with Phosphothreonine" [UniProtKB:Q99081] xref: UniProtKB:Q99081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058408 ! HTF4_HUMAN [Term] id: CCO:B0066940 name: HTF4_HUMAN-Phosphoserine333 def: "Protein HTF4_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q99081] xref: UniProtKB:Q99081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058408 ! HTF4_HUMAN [Term] id: CCO:B0066941 name: HTSF1_HUMAN-Phosphoserine387 def: "Protein HTSF1_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066942 name: HTSF1_HUMAN-Phosphoserine481 def: "Protein HTSF1_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066943 name: HTSF1_HUMAN-Phosphoserine494 def: "Protein HTSF1_HUMAN with the residue 494 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066944 name: HTSF1_HUMAN-Phosphoserine498 def: "Protein HTSF1_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066945 name: HTSF1_HUMAN-Phosphoserine557 def: "Protein HTSF1_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066946 name: HTSF1_HUMAN-Phosphoserine561 def: "Protein HTSF1_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066947 name: HTSF1_HUMAN-Phosphoserine579 def: "Protein HTSF1_HUMAN with the residue 579 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066948 name: HTSF1_HUMAN-Phosphoserine597 def: "Protein HTSF1_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066949 name: HTSF1_HUMAN-Phosphoserine600 def: "Protein HTSF1_HUMAN with the residue 600 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066950 name: HTSF1_HUMAN-Phosphoserine607 def: "Protein HTSF1_HUMAN with the residue 607 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066951 name: HTSF1_HUMAN-Phosphoserine616 def: "Protein HTSF1_HUMAN with the residue 616 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066952 name: HTSF1_HUMAN-Phosphoserine624 def: "Protein HTSF1_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066953 name: HTSF1_HUMAN-Phosphoserine642 def: "Protein HTSF1_HUMAN with the residue 642 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066954 name: HTSF1_HUMAN-Phosphoserine676 def: "Protein HTSF1_HUMAN with the residue 676 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066955 name: HTSF1_HUMAN-Phosphoserine702 def: "Protein HTSF1_HUMAN with the residue 702 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066956 name: HTSF1_HUMAN-Phosphoserine713 def: "Protein HTSF1_HUMAN with the residue 713 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066957 name: HTSF1_HUMAN-Phosphoserine714 def: "Protein HTSF1_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066958 name: HTSF1_HUMAN-Phosphoserine721 def: "Protein HTSF1_HUMAN with the residue 721 substituted with Phosphoserine" [UniProtKB:O43719] xref: UniProtKB:O43719 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:B0066959 name: HUWE1_HUMAN-Phosphoserine1368 def: "Protein HUWE1_HUMAN with the residue 1368 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0066960 name: HUWE1_HUMAN-Phosphoserine2365 def: "Protein HUWE1_HUMAN with the residue 2365 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0066961 name: HUWE1_HUMAN-Phosphoserine3662 def: "Protein HUWE1_HUMAN with the residue 3662 substituted with Phosphoserine" [UniProtKB:Q7Z6Z7] xref: UniProtKB:Q7Z6Z7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:B0066962 name: HXB2_HUMAN-Phosphothreonine52 def: "Protein HXB2_HUMAN with the residue 52 substituted with Phosphothreonine" [UniProtKB:P14652] xref: UniProtKB:P14652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055027 ! HXB2_HUMAN [Term] id: CCO:B0066963 name: HXB2_HUMAN-Phosphoserine55 def: "Protein HXB2_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:P14652] xref: UniProtKB:P14652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055027 ! HXB2_HUMAN [Term] id: CCO:B0066964 name: HXC10_HUMAN-Phosphoserine189 def: "Protein HXC10_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q9NYD6] xref: UniProtKB:Q9NYD6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005451 ! HXC10_HUMAN [Term] id: CCO:B0066965 name: HXD11_HUMAN-Phosphoserine203 def: "Protein HXD11_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:P31277] xref: UniProtKB:P31277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055242 ! HXD11_HUMAN [Term] id: CCO:B0066966 name: HXK1_HUMAN-Phosphotyrosine27 def: "Protein HXK1_HUMAN with the residue 27 substituted with Phosphotyrosine" [UniProtKB:P19367] comment: By similarity xref: UniProtKB:P19367 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000807 ! hexokinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0018524 ! HXK1_HUMAN [Term] id: CCO:B0066967 name: I18RA_HUMAN-Phosphothreonine401 def: "Protein I18RA_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:O95256] xref: UniProtKB:O95256 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054740 ! I18RA_HUMAN [Term] id: CCO:B0066968 name: I2BP1_HUMAN-Phosphoserine66 def: "Protein I2BP1_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q8IU81] xref: UniProtKB:Q8IU81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057319 ! I2BP1_HUMAN [Term] id: CCO:B0066969 name: I2BP1_HUMAN-Phosphoserine125 def: "Protein I2BP1_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q8IU81] xref: UniProtKB:Q8IU81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057319 ! I2BP1_HUMAN [Term] id: CCO:B0066970 name: I2BP1_HUMAN-Phosphoserine186 def: "Protein I2BP1_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:Q8IU81] xref: UniProtKB:Q8IU81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057319 ! I2BP1_HUMAN [Term] id: CCO:B0066971 name: I2BP1_HUMAN-Phosphoserine421 def: "Protein I2BP1_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q8IU81] xref: UniProtKB:Q8IU81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057319 ! I2BP1_HUMAN [Term] id: CCO:B0066972 name: I2BP1_HUMAN-Phosphoserine436 def: "Protein I2BP1_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q8IU81] xref: UniProtKB:Q8IU81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057319 ! I2BP1_HUMAN [Term] id: CCO:B0066973 name: I2BP1_HUMAN-Phosphoserine453 def: "Protein I2BP1_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q8IU81] xref: UniProtKB:Q8IU81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057319 ! I2BP1_HUMAN [Term] id: CCO:B0066974 name: I2BP1_HUMAN-Phosphoserine457 def: "Protein I2BP1_HUMAN with the residue 457 substituted with Phosphoserine" [UniProtKB:Q8IU81] xref: UniProtKB:Q8IU81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057319 ! I2BP1_HUMAN [Term] id: CCO:B0066975 name: I2BP2_HUMAN-Phosphoserine360 def: "Protein I2BP2_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q7Z5L9] xref: UniProtKB:Q7Z5L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057183 ! I2BP2_HUMAN [Term] id: CCO:B0066976 name: I2BP2_HUMAN-Phosphoserine455 def: "Protein I2BP2_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q7Z5L9] xref: UniProtKB:Q7Z5L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057183 ! I2BP2_HUMAN [Term] id: CCO:B0066977 name: I2BP2_HUMAN-Phosphoserine457 def: "Protein I2BP2_HUMAN with the residue 457 substituted with Phosphoserine" [UniProtKB:Q7Z5L9] xref: UniProtKB:Q7Z5L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057183 ! I2BP2_HUMAN [Term] id: CCO:B0066978 name: I2BP2_HUMAN-Phosphoserine460 def: "Protein I2BP2_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q7Z5L9] xref: UniProtKB:Q7Z5L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057183 ! I2BP2_HUMAN [Term] id: CCO:B0066979 name: IAPP_HUMAN-Tyrosine amide70 def: "Protein IAPP_HUMAN with the residue 70 substituted with Tyrosine amide" [UniProtKB:P10997] xref: UniProtKB:P10997 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0054984 ! IAPP_HUMAN [Term] id: CCO:B0066980 name: IASPP_HUMAN-Phosphoserine102 def: "Protein IASPP_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066981 name: IASPP_HUMAN-Phosphoserine110 def: "Protein IASPP_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066982 name: IASPP_HUMAN-Phosphoserine113 def: "Protein IASPP_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066983 name: IASPP_HUMAN-Phosphoserine119 def: "Protein IASPP_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066984 name: IASPP_HUMAN-Phosphoserine120 def: "Protein IASPP_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066985 name: IASPP_HUMAN-Phosphothreonine123 def: "Protein IASPP_HUMAN with the residue 123 substituted with Phosphothreonine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066986 name: IASPP_HUMAN-Phosphoserine134 def: "Protein IASPP_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066987 name: IASPP_HUMAN-Phosphoserine158 def: "Protein IASPP_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066988 name: IASPP_HUMAN-Phosphoserine183 def: "Protein IASPP_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066989 name: IASPP_HUMAN-Phosphoserine187 def: "Protein IASPP_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066990 name: IASPP_HUMAN-Phosphoserine203 def: "Protein IASPP_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066991 name: IASPP_HUMAN-Phosphoserine225 def: "Protein IASPP_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066992 name: IASPP_HUMAN-Phosphoserine316 def: "Protein IASPP_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066993 name: IASPP_HUMAN-Phosphoserine332 def: "Protein IASPP_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066994 name: IASPP_HUMAN-Phosphoserine526 def: "Protein IASPP_HUMAN with the residue 526 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066995 name: IASPP_HUMAN-Phosphoserine567 def: "Protein IASPP_HUMAN with the residue 567 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066996 name: IASPP_HUMAN-Phosphoserine597 def: "Protein IASPP_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:Q8WUF5] xref: UniProtKB:Q8WUF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057979 ! IASPP_HUMAN [Term] id: CCO:B0066997 name: IBP1_HUMAN-Phosphoserine126 def: "Protein IBP1_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:P08833] xref: UniProtKB:P08833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001651 ! insulin-like growth factor binding relationship: has_function CCO:F0004188 ! growth factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: transformation_of CCO:B0054932 ! IBP1_HUMAN [Term] id: CCO:B0066998 name: IBP1_HUMAN-Phosphoserine144 def: "Protein IBP1_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:P08833] xref: UniProtKB:P08833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054932 ! IBP1_HUMAN [Term] id: CCO:B0066999 name: IBP1_HUMAN-Phosphoserine194 def: "Protein IBP1_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:P08833] xref: UniProtKB:P08833 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054932 ! IBP1_HUMAN [Term] id: CCO:B0067000 name: ICK_HUMAN-Phosphotyrosine156 def: "Protein ICK_HUMAN with the residue 156 substituted with Phosphotyrosine" [UniProtKB:Q9UPZ9] xref: UniProtKB:Q9UPZ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018166 ! ICK_HUMAN [Term] id: CCO:B0067001 name: ICLN_HUMAN-N-acetylserine2 def: "Protein ICLN_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P54105] xref: UniProtKB:P54105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063508 ! ICLN_HUMAN [Term] id: CCO:B0067002 name: ICLN_HUMAN-Phosphoserine102 def: "Protein ICLN_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:P54105] xref: UniProtKB:P54105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0063508 ! ICLN_HUMAN [Term] id: CCO:B0067003 name: ICLN_HUMAN-Phosphoserine193 def: "Protein ICLN_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:P54105] xref: UniProtKB:P54105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063508 ! ICLN_HUMAN [Term] id: CCO:B0067004 name: ICLN_HUMAN-Phosphothreonine223 def: "Protein ICLN_HUMAN with the residue 223 substituted with Phosphothreonine" [UniProtKB:P54105] xref: UniProtKB:P54105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063508 ! ICLN_HUMAN [Term] id: CCO:B0067005 name: IF16_HUMAN-Phosphoserine106 def: "Protein IF16_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q16666] xref: UniProtKB:Q16666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056172 ! IF16_HUMAN [Term] id: CCO:B0067006 name: IF16_HUMAN-Phosphoserine153 def: "Protein IF16_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:Q16666] xref: UniProtKB:Q16666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056172 ! IF16_HUMAN [Term] id: CCO:B0067007 name: IF2B1_HUMAN-Phosphoserine181 def: "Protein IF2B1_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q9NZI8] xref: UniProtKB:Q9NZI8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059000 ! IF2B1_HUMAN [Term] id: CCO:B0067008 name: IF2B2_HUMAN-Phosphoserine162 def: "Protein IF2B2_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:Q9Y6M1] xref: UniProtKB:Q9Y6M1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059410 ! IF2B2_HUMAN [Term] id: CCO:B0067009 name: IF2B2_HUMAN-Phosphoserine164 def: "Protein IF2B2_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q9Y6M1] xref: UniProtKB:Q9Y6M1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059410 ! IF2B2_HUMAN [Term] id: CCO:B0067010 name: IF2M_HUMAN-Phosphothreonine688 def: "Protein IF2M_HUMAN with the residue 688 substituted with Phosphothreonine" [UniProtKB:P46199] comment: By similarity xref: UniProtKB:P46199 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_function CCO:F0005786 ! ribosomal small subunit binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0023063 ! IF2M_HUMAN [Term] id: CCO:B0067011 name: IF2P_HUMAN-Phosphoserine107 def: "Protein IF2P_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067012 name: IF2P_HUMAN-Phosphoserine113 def: "Protein IF2P_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067013 name: IF2P_HUMAN-Phosphoserine135 def: "Protein IF2P_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067014 name: IF2P_HUMAN-Phosphoserine137 def: "Protein IF2P_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067015 name: IF2P_HUMAN-Phosphoserine164 def: "Protein IF2P_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067016 name: IF2P_HUMAN-Phosphoserine182 def: "Protein IF2P_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067017 name: IF2P_HUMAN-Phosphoserine183 def: "Protein IF2P_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067018 name: IF2P_HUMAN-Phosphoserine186 def: "Protein IF2P_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067019 name: IF2P_HUMAN-Phosphoserine190 def: "Protein IF2P_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067020 name: IF2P_HUMAN-Phosphoserine214 def: "Protein IF2P_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067021 name: IF2P_HUMAN-Phosphoserine1168 def: "Protein IF2P_HUMAN with the residue 1168 substituted with Phosphoserine" [UniProtKB:O60841] xref: UniProtKB:O60841 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:B0067022 name: IF4A1_HUMAN-Phosphothreonine158 def: "Protein IF4A1_HUMAN with the residue 158 substituted with Phosphothreonine" [UniProtKB:P60842] xref: UniProtKB:P60842 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005679 ! IF4A1_HUMAN [Term] id: CCO:B0067023 name: IF4A3_HUMAN-N-acetylalanine2 def: "Protein IF4A3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P38919] xref: UniProtKB:P38919 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055320 ! IF4A3_HUMAN [Term] id: CCO:B0067024 name: IF4A3_HUMAN-Phosphothreonine163 def: "Protein IF4A3_HUMAN with the residue 163 substituted with Phosphothreonine" [UniProtKB:P38919] xref: UniProtKB:P38919 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055320 ! IF4A3_HUMAN [Term] id: CCO:B0067025 name: IF4B_HUMAN-Phosphoserine497 def: "Protein IF4B_HUMAN with the residue 497 substituted with Phosphoserine" [UniProtKB:P23588] comment: By similarity xref: UniProtKB:P23588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:B0067026 name: IF4G1_HUMAN-Phosphothreonine205 def: "Protein IF4G1_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067027 name: IF4G1_HUMAN-Phosphothreonine207 def: "Protein IF4G1_HUMAN with the residue 207 substituted with Phosphothreonine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067028 name: IF4G1_HUMAN-Phosphothreonine223 def: "Protein IF4G1_HUMAN with the residue 223 substituted with Phosphothreonine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067029 name: IF4G1_HUMAN-Phosphotyrosine594 def: "Protein IF4G1_HUMAN with the residue 594 substituted with Phosphotyrosine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067030 name: IF4G1_HUMAN-Phosphothreonine647 def: "Protein IF4G1_HUMAN with the residue 647 substituted with Phosphothreonine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067031 name: IF4G1_HUMAN-Phosphoserine1093 def: "Protein IF4G1_HUMAN with the residue 1093 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067032 name: IF4G1_HUMAN-Phosphoserine1146 def: "Protein IF4G1_HUMAN with the residue 1146 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067033 name: IF4G1_HUMAN-Phosphoserine1148 def: "Protein IF4G1_HUMAN with the residue 1148 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067034 name: IF4G1_HUMAN-Phosphoserine1186 def: "Protein IF4G1_HUMAN with the residue 1186 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067035 name: IF4G1_HUMAN-Phosphoserine1188 def: "Protein IF4G1_HUMAN with the residue 1188 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067036 name: IF4G1_HUMAN-Phosphoserine1210 def: "Protein IF4G1_HUMAN with the residue 1210 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067037 name: IF4G1_HUMAN-Phosphoserine1232 def: "Protein IF4G1_HUMAN with the residue 1232 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067038 name: IF4G1_HUMAN-Phosphoserine1597 def: "Protein IF4G1_HUMAN with the residue 1597 substituted with Phosphoserine" [UniProtKB:Q04637] xref: UniProtKB:Q04637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:B0067039 name: IF4G2_HUMAN-Phosphothreonine514 def: "Protein IF4G2_HUMAN with the residue 514 substituted with Phosphothreonine" [UniProtKB:P78344] xref: UniProtKB:P78344 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001699 ! IF4G2_HUMAN [Term] id: CCO:B0067040 name: IF4G3_HUMAN-Phosphoserine230 def: "Protein IF4G3_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:O43432] xref: UniProtKB:O43432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016344 ! IF4G3_HUMAN [Term] id: CCO:B0067041 name: IF4G3_HUMAN-Phosphoserine232 def: "Protein IF4G3_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:O43432] xref: UniProtKB:O43432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000071 ! RNA cap binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: transformation_of CCO:B0016344 ! IF4G3_HUMAN [Term] id: CCO:B0067042 name: IF4G3_HUMAN-Phosphoserine267 def: "Protein IF4G3_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:O43432] comment: By similarity xref: UniProtKB:O43432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016344 ! IF4G3_HUMAN [Term] id: CCO:B0067043 name: IF4G3_HUMAN-Phosphoserine495 def: "Protein IF4G3_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:O43432] xref: UniProtKB:O43432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016344 ! IF4G3_HUMAN [Term] id: CCO:B0067044 name: IF4G3_HUMAN-Phosphoserine1156 def: "Protein IF4G3_HUMAN with the residue 1156 substituted with Phosphoserine" [UniProtKB:O43432] comment: by CaMK1; xref: UniProtKB:O43432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016344 ! IF4G3_HUMAN [Term] id: CCO:B0067045 name: IF4H_HUMAN-N-acetylalanine2 def: "Protein IF4H_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q15056] xref: UniProtKB:Q15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056040 ! IF4H_HUMAN [Term] id: CCO:B0067046 name: IF4H_HUMAN-Phosphotyrosine12 def: "Protein IF4H_HUMAN with the residue 12 substituted with Phosphotyrosine" [UniProtKB:Q15056] xref: UniProtKB:Q15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056040 ! IF4H_HUMAN [Term] id: CCO:B0067047 name: IF4H_HUMAN-Phosphotyrosine45 def: "Protein IF4H_HUMAN with the residue 45 substituted with Phosphotyrosine" [UniProtKB:Q15056] xref: UniProtKB:Q15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056040 ! IF4H_HUMAN [Term] id: CCO:B0067048 name: IF4H_HUMAN-Phosphotyrosine101 def: "Protein IF4H_HUMAN with the residue 101 substituted with Phosphotyrosine" [UniProtKB:Q15056] xref: UniProtKB:Q15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056040 ! IF4H_HUMAN [Term] id: CCO:B0067049 name: IF4H_HUMAN-Phosphoserine193 def: "Protein IF4H_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:Q15056] xref: UniProtKB:Q15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001739 ! translation factor activity, nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000778 ! eukaryotic translation initiation factor 4F complex relationship: transformation_of CCO:B0056040 ! IF4H_HUMAN [Term] id: CCO:B0067050 name: IF5_HUMAN-Phosphoserine10 def: "Protein IF5_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0067051 name: IF5_HUMAN-Phosphoserine229 def: "Protein IF5_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0067052 name: IF5_HUMAN-Phosphoserine419 def: "Protein IF5_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:P55010] xref: UniProtKB:P55010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051549 ! IF5_HUMAN [Term] id: CCO:B0067053 name: IF6_HUMAN-Phosphotyrosine113 def: "Protein IF6_HUMAN with the residue 113 substituted with Phosphotyrosine" [UniProtKB:P56537] xref: UniProtKB:P56537 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063158 ! IF6_HUMAN [Term] id: CCO:B0067054 name: IF6_HUMAN-Phosphoserine174 def: "Protein IF6_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:P56537] comment: by CK1; xref: UniProtKB:P56537 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063158 ! IF6_HUMAN [Term] id: CCO:B0067055 name: IF6_HUMAN-Phosphoserine175 def: "Protein IF6_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:P56537] comment: by CK1; xref: UniProtKB:P56537 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063158 ! IF6_HUMAN [Term] id: CCO:B0067056 name: IF6_HUMAN-Phosphoserine239 def: "Protein IF6_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:P56537] xref: UniProtKB:P56537 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063158 ! IF6_HUMAN [Term] id: CCO:B0067057 name: IF6_HUMAN-Phosphoserine243 def: "Protein IF6_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:P56537] xref: UniProtKB:P56537 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005784 ! ribosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063158 ! IF6_HUMAN [Term] id: CCO:B0067058 name: IFIH1_HUMAN-Phosphoserine289 def: "Protein IFIH1_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q9BYX4] comment: By similarity xref: UniProtKB:Q9BYX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058587 ! IFIH1_HUMAN [Term] id: CCO:B0067059 name: IFIH1_HUMAN-Phosphoserine301 def: "Protein IFIH1_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:Q9BYX4] comment: By similarity xref: UniProtKB:Q9BYX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058587 ! IFIH1_HUMAN [Term] id: CCO:B0067060 name: IFIH1_HUMAN-Phosphoserine645 def: "Protein IFIH1_HUMAN with the residue 645 substituted with Phosphoserine" [UniProtKB:Q9BYX4] comment: By similarity xref: UniProtKB:Q9BYX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058587 ! IFIH1_HUMAN [Term] id: CCO:B0067061 name: IFRD1_HUMAN-Phosphoserine21 def: "Protein IFRD1_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:O00458] xref: UniProtKB:O00458 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063533 ! IFRD1_HUMAN [Term] id: CCO:B0067062 name: IGSF8_HUMAN-Phosphoserine12 def: "Protein IGSF8_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q969P0] comment: By similarity xref: UniProtKB:Q969P0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058136 ! IGSF8_HUMAN [Term] id: CCO:B0067063 name: IKBE_HUMAN-Phosphoserine157 def: "Protein IKBE_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:O00221] comment: Probable xref: UniProtKB:O00221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:B0067064 name: IKBE_HUMAN-Phosphoserine161 def: "Protein IKBE_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:O00221] comment: Probable xref: UniProtKB:O00221 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:B0067065 name: IKBP1_HUMAN-Phosphoserine56 def: "Protein IKBP1_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:Q5VVH5] comment: By similarity xref: UniProtKB:Q5VVH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056658 ! IKBP1_HUMAN [Term] id: CCO:B0067066 name: IKBP1_HUMAN-Phosphoserine62 def: "Protein IKBP1_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q5VVH5] comment: By similarity xref: UniProtKB:Q5VVH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056658 ! IKBP1_HUMAN [Term] id: CCO:B0067067 name: IKBP1_HUMAN-Phosphoserine235 def: "Protein IKBP1_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q5VVH5] comment: By similarity xref: UniProtKB:Q5VVH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056658 ! IKBP1_HUMAN [Term] id: CCO:B0067068 name: IKBP1_HUMAN-Phosphothreonine237 def: "Protein IKBP1_HUMAN with the residue 237 substituted with Phosphothreonine" [UniProtKB:Q5VVH5] comment: By similarity xref: UniProtKB:Q5VVH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056658 ! IKBP1_HUMAN [Term] id: CCO:B0067069 name: IKBP1_HUMAN-Phosphoserine242 def: "Protein IKBP1_HUMAN with the residue 242 substituted with Phosphoserine" [UniProtKB:Q5VVH5] comment: By similarity xref: UniProtKB:Q5VVH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056658 ! IKBP1_HUMAN [Term] id: CCO:B0067070 name: IKBP1_HUMAN-Phosphothreonine247 def: "Protein IKBP1_HUMAN with the residue 247 substituted with Phosphothreonine" [UniProtKB:Q5VVH5] comment: By similarity xref: UniProtKB:Q5VVH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056658 ! IKBP1_HUMAN [Term] id: CCO:B0067071 name: IKZF3_HUMAN-Phosphothreonine169 def: "Protein IKZF3_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:Q9UKT9] xref: UniProtKB:Q9UKT9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038370 ! IKZF3_HUMAN [Term] id: CCO:B0067072 name: IL1AP_HUMAN-Phosphothreonine395 def: "Protein IL1AP_HUMAN with the residue 395 substituted with Phosphothreonine" [UniProtKB:Q9NPH3] comment: By similarity xref: UniProtKB:Q9NPH3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058853 ! IL1AP_HUMAN [Term] id: CCO:B0067073 name: IL1AP_HUMAN-Phosphothreonine398 def: "Protein IL1AP_HUMAN with the residue 398 substituted with Phosphothreonine" [UniProtKB:Q9NPH3] comment: By similarity xref: UniProtKB:Q9NPH3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058853 ! IL1AP_HUMAN [Term] id: CCO:B0067074 name: IL2RG_HUMAN-Phosphothreonine161 def: "Protein IL2RG_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:P31785] comment: By similarity xref: UniProtKB:P31785 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055246 ! IL2RG_HUMAN [Term] id: CCO:B0067075 name: IL2RG_HUMAN-Phosphotyrosine325 def: "Protein IL2RG_HUMAN with the residue 325 substituted with Phosphotyrosine" [UniProtKB:P31785] comment: By similarity xref: UniProtKB:P31785 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001258 ! interleukin-2 receptor activity relationship: has_function CCO:F0001260 ! interleukin-4 receptor activity relationship: has_function CCO:F0001263 ! interleukin-7 receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004240 ! interleukin-2 binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055246 ! IL2RG_HUMAN [Term] id: CCO:B0067076 name: IL4RA_HUMAN-Phosphotyrosine497 def: "Protein IL4RA_HUMAN with the residue 497 substituted with Phosphotyrosine" [UniProtKB:P24394] xref: UniProtKB:P24394 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055171 ! IL4RA_HUMAN [Term] id: CCO:B0067077 name: IL4RA_HUMAN-Phosphotyrosine575 def: "Protein IL4RA_HUMAN with the residue 575 substituted with Phosphotyrosine" [UniProtKB:P24394] comment: Probable xref: UniProtKB:P24394 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055171 ! IL4RA_HUMAN [Term] id: CCO:B0067078 name: IL4RA_HUMAN-Phosphotyrosine603 def: "Protein IL4RA_HUMAN with the residue 603 substituted with Phosphotyrosine" [UniProtKB:P24394] comment: Probable xref: UniProtKB:P24394 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055171 ! IL4RA_HUMAN [Term] id: CCO:B0067079 name: IL4RA_HUMAN-Phosphotyrosine631 def: "Protein IL4RA_HUMAN with the residue 631 substituted with Phosphotyrosine" [UniProtKB:P24394] comment: Probable xref: UniProtKB:P24394 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001260 ! interleukin-4 receptor activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055171 ! IL4RA_HUMAN [Term] id: CCO:B0067080 name: IL7RA_HUMAN-Phosphotyrosine159 def: "Protein IL7RA_HUMAN with the residue 159 substituted with Phosphotyrosine" [UniProtKB:P16871] xref: UniProtKB:P16871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055060 ! IL7RA_HUMAN [Term] id: CCO:B0067081 name: IL7RA_HUMAN-Phosphotyrosine169 def: "Protein IL7RA_HUMAN with the residue 169 substituted with Phosphotyrosine" [UniProtKB:P16871] xref: UniProtKB:P16871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001263 ! interleukin-7 receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055060 ! IL7RA_HUMAN [Term] id: CCO:B0067082 name: IL7RA_HUMAN-Phosphothreonine282 def: "Protein IL7RA_HUMAN with the residue 282 substituted with Phosphothreonine" [UniProtKB:P16871] comment: by PKC; Potential xref: UniProtKB:P16871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055060 ! IL7RA_HUMAN [Term] id: CCO:B0067083 name: ILF2_HUMAN-Phosphothreonine388 def: "Protein ILF2_HUMAN with the residue 388 substituted with Phosphothreonine" [UniProtKB:Q12905] xref: UniProtKB:Q12905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055855 ! ILF2_HUMAN [Term] id: CCO:B0067084 name: ILF3_HUMAN-Phosphotyrosine579 def: "Protein ILF3_HUMAN with the residue 579 substituted with Phosphotyrosine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0067085 name: ILF3_HUMAN-Phosphoserine792 def: "Protein ILF3_HUMAN with the residue 792 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0067086 name: ILF3_HUMAN-Phosphoserine810 def: "Protein ILF3_HUMAN with the residue 810 substituted with Phosphoserine" [UniProtKB:Q12906] xref: UniProtKB:Q12906 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001734 ! ILF3_HUMAN [Term] id: CCO:B0067087 name: IMB1_HUMAN-Phosphoserine12 def: "Protein IMB1_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q14974] xref: UniProtKB:Q14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005409 ! IMB1_HUMAN [Term] id: CCO:B0067088 name: IMDH2_HUMAN-Phosphotyrosine400 def: "Protein IMDH2_HUMAN with the residue 400 substituted with Phosphotyrosine" [UniProtKB:P12268] xref: UniProtKB:P12268 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054998 ! IMDH2_HUMAN [Term] id: CCO:B0067089 name: IN80B_HUMAN-Phosphoserine84 def: "Protein IN80B_HUMAN with the residue 84 substituted with Phosphoserine" [UniProtKB:Q9C086] xref: UniProtKB:Q9C086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061990 ! IN80B_HUMAN [Term] id: CCO:B0067090 name: IN80B_HUMAN-Phosphoserine86 def: "Protein IN80B_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q9C086] xref: UniProtKB:Q9C086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061990 ! IN80B_HUMAN [Term] id: CCO:B0067091 name: IN80B_HUMAN-Phosphoserine117 def: "Protein IN80B_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q9C086] xref: UniProtKB:Q9C086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061990 ! IN80B_HUMAN [Term] id: CCO:B0067092 name: IN80B_HUMAN-Phosphoserine119 def: "Protein IN80B_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q9C086] xref: UniProtKB:Q9C086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061990 ! IN80B_HUMAN [Term] id: CCO:B0067093 name: INADL_HUMAN-Phosphoserine455 def: "Protein INADL_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q8NI35] comment: By similarity xref: UniProtKB:Q8NI35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0057881 ! INADL_HUMAN [Term] id: CCO:B0067094 name: INADL_HUMAN-Phosphoserine522 def: "Protein INADL_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q8NI35] xref: UniProtKB:Q8NI35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057881 ! INADL_HUMAN [Term] id: CCO:B0067095 name: INADL_HUMAN-Phosphoserine645 def: "Protein INADL_HUMAN with the residue 645 substituted with Phosphoserine" [UniProtKB:Q8NI35] xref: UniProtKB:Q8NI35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057881 ! INADL_HUMAN [Term] id: CCO:B0067096 name: INADL_HUMAN-Phosphothreonine1209 def: "Protein INADL_HUMAN with the residue 1209 substituted with Phosphothreonine" [UniProtKB:Q8NI35] xref: UniProtKB:Q8NI35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057881 ! INADL_HUMAN [Term] id: CCO:B0067097 name: INADL_HUMAN-Phosphoserine1212 def: "Protein INADL_HUMAN with the residue 1212 substituted with Phosphoserine" [UniProtKB:Q8NI35] xref: UniProtKB:Q8NI35 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057881 ! INADL_HUMAN [Term] id: CCO:B0067098 name: INAR1_HUMAN-Phosphotyrosine466 def: "Protein INAR1_HUMAN with the residue 466 substituted with Phosphotyrosine" [UniProtKB:P17181] comment: by TYK2; Probable xref: UniProtKB:P17181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055085 ! INAR1_HUMAN [Term] id: CCO:B0067099 name: INAR1_HUMAN-Phosphotyrosine481 def: "Protein INAR1_HUMAN with the residue 481 substituted with Phosphotyrosine" [UniProtKB:P17181] comment: by TYK2; Probable xref: UniProtKB:P17181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001251 ! interferon receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008346 ! type I interferon receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055085 ! INAR1_HUMAN [Term] id: CCO:B0067100 name: INCE_HUMAN-Phosphothreonine145 def: "Protein INCE_HUMAN with the residue 145 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067101 name: INCE_HUMAN-Phosphoserine218 def: "Protein INCE_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067102 name: INCE_HUMAN-Phosphoserine446 def: "Protein INCE_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067103 name: INCE_HUMAN-Phosphothreonine507 def: "Protein INCE_HUMAN with the residue 507 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067104 name: INCE_HUMAN-Phosphothreonine509 def: "Protein INCE_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067105 name: INCE_HUMAN-Phosphoserine510 def: "Protein INCE_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067106 name: INCE_HUMAN-Phosphoserine514 def: "Protein INCE_HUMAN with the residue 514 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067107 name: INCE_HUMAN-Phosphoserine828 def: "Protein INCE_HUMAN with the residue 828 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067108 name: INCE_HUMAN-Phosphoserine831 def: "Protein INCE_HUMAN with the residue 831 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067109 name: INCE_HUMAN-Phosphothreonine832 def: "Protein INCE_HUMAN with the residue 832 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067110 name: INCE_HUMAN-Phosphothreonine892 def: "Protein INCE_HUMAN with the residue 892 substituted with Phosphothreonine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067111 name: INCE_HUMAN-Phosphoserine893 def: "Protein INCE_HUMAN with the residue 893 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067112 name: INCE_HUMAN-Phosphoserine894 def: "Protein INCE_HUMAN with the residue 894 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067113 name: INCE_HUMAN-Phosphoserine914 def: "Protein INCE_HUMAN with the residue 914 substituted with Phosphoserine" [UniProtKB:Q9NQS7] xref: UniProtKB:Q9NQS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002154 ! INCE_HUMAN [Term] id: CCO:B0067114 name: INGR1_HUMAN-Phosphoserine369 def: "Protein INGR1_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:P15260] comment: By similarity xref: UniProtKB:P15260 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001253 ! interferon-gamma receptor activity relationship: has_function CCO:F0004221 ! cytokine binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055033 ! INGR1_HUMAN [Term] id: CCO:B0067115 name: INGR2_HUMAN-Phosphoserine198 def: "Protein INGR2_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:P38484] xref: UniProtKB:P38484 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001253 ! interferon-gamma receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055319 ! INGR2_HUMAN [Term] id: CCO:B0067116 name: INO80_HUMAN-Phosphoserine1490 def: "Protein INO80_HUMAN with the residue 1490 substituted with Phosphoserine" [UniProtKB:Q9ULG1] xref: UniProtKB:Q9ULG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061991 ! INO80_HUMAN [Term] id: CCO:B0067117 name: INO80_HUMAN-Phosphoserine1512 def: "Protein INO80_HUMAN with the residue 1512 substituted with Phosphoserine" [UniProtKB:Q9ULG1] xref: UniProtKB:Q9ULG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061991 ! INO80_HUMAN [Term] id: CCO:B0067118 name: INO80_HUMAN-Phosphoserine1516 def: "Protein INO80_HUMAN with the residue 1516 substituted with Phosphoserine" [UniProtKB:Q9ULG1] xref: UniProtKB:Q9ULG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061991 ! INO80_HUMAN [Term] id: CCO:B0067119 name: INO80_HUMAN-Phosphothreonine1550 def: "Protein INO80_HUMAN with the residue 1550 substituted with Phosphothreonine" [UniProtKB:Q9ULG1] xref: UniProtKB:Q9ULG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0061991 ! INO80_HUMAN [Term] id: CCO:B0067120 name: INSRR_HUMAN-Phosphotyrosine1145 def: "Protein INSRR_HUMAN with the residue 1145 substituted with Phosphotyrosine" [UniProtKB:P14616] comment: by autocatalysis; By similarity xref: UniProtKB:P14616 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0029069 ! INSRR_HUMAN [Term] id: CCO:B0067121 name: IPO9_HUMAN-N-acetylalanine2 def: "Protein IPO9_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q96P70] xref: UniProtKB:Q96P70 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001985 ! Ran GTPase binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063077 ! IPO9_HUMAN [Term] id: CCO:B0067122 name: IPP2L_HUMAN-Phosphothreonine73 def: "Protein IPP2L_HUMAN with the residue 73 substituted with Phosphothreonine" [UniProtKB:Q96PQ5] comment: by GSK3; By similarity xref: UniProtKB:Q96PQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058341 ! IPP2L_HUMAN [Term] id: CCO:B0067123 name: IPP2L_HUMAN-Phosphoserine87 def: "Protein IPP2L_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q96PQ5] comment: by CK2; By similarity xref: UniProtKB:Q96PQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058341 ! IPP2L_HUMAN [Term] id: CCO:B0067124 name: IPP2L_HUMAN-Phosphoserine121 def: "Protein IPP2L_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q96PQ5] comment: By similarity xref: UniProtKB:Q96PQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058341 ! IPP2L_HUMAN [Term] id: CCO:B0067125 name: IPP2L_HUMAN-Phosphoserine122 def: "Protein IPP2L_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q96PQ5] comment: By similarity xref: UniProtKB:Q96PQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058341 ! IPP2L_HUMAN [Term] id: CCO:B0067126 name: IPP2M_HUMAN-Phosphoserine121 def: "Protein IPP2M_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q6NXS1] comment: By similarity xref: UniProtKB:Q6NXS1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056868 ! IPP2M_HUMAN [Term] id: CCO:B0067127 name: IPP2M_HUMAN-Phosphoserine122 def: "Protein IPP2M_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q6NXS1] comment: By similarity xref: UniProtKB:Q6NXS1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056868 ! IPP2M_HUMAN [Term] id: CCO:B0067128 name: IPP2_HUMAN-Phosphoserine20 def: "Protein IPP2_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P41236] xref: UniProtKB:P41236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055339 ! IPP2_HUMAN [Term] id: CCO:B0067129 name: IPP2_HUMAN-Phosphothreonine73 def: "Protein IPP2_HUMAN with the residue 73 substituted with Phosphothreonine" [UniProtKB:P41236] comment: by GSK3; By similarity xref: UniProtKB:P41236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055339 ! IPP2_HUMAN [Term] id: CCO:B0067130 name: IPP2_HUMAN-Phosphoserine87 def: "Protein IPP2_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:P41236] xref: UniProtKB:P41236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055339 ! IPP2_HUMAN [Term] id: CCO:B0067131 name: IPP2_HUMAN-Phosphothreonine89 def: "Protein IPP2_HUMAN with the residue 89 substituted with Phosphothreonine" [UniProtKB:P41236] xref: UniProtKB:P41236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055339 ! IPP2_HUMAN [Term] id: CCO:B0067132 name: IPP2_HUMAN-Phosphothreonine92 def: "Protein IPP2_HUMAN with the residue 92 substituted with Phosphothreonine" [UniProtKB:P41236] xref: UniProtKB:P41236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001221 ! type 1 serine/threonine specific protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055339 ! IPP2_HUMAN [Term] id: CCO:B0067133 name: IPP2_HUMAN-Phosphoserine121 def: "Protein IPP2_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:P41236] xref: UniProtKB:P41236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055339 ! IPP2_HUMAN [Term] id: CCO:B0067134 name: IPP2_HUMAN-Phosphoserine122 def: "Protein IPP2_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:P41236] xref: UniProtKB:P41236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055339 ! IPP2_HUMAN [Term] id: CCO:B0067135 name: IQCB1_HUMAN-Phosphoserine572 def: "Protein IQCB1_HUMAN with the residue 572 substituted with Phosphoserine" [UniProtKB:Q15051] xref: UniProtKB:Q15051 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0001443 ! photoreceptor connecting cilium relationship: transformation_of CCO:B0056038 ! IQCB1_HUMAN [Term] id: CCO:B0067136 name: IQEC1_HUMAN-Phosphoserine107 def: "Protein IQEC1_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:Q6DN90] comment: By similarity xref: UniProtKB:Q6DN90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056728 ! IQEC1_HUMAN [Term] id: CCO:B0067137 name: IQEC1_HUMAN-Phosphoserine180 def: "Protein IQEC1_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:Q6DN90] xref: UniProtKB:Q6DN90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056728 ! IQEC1_HUMAN [Term] id: CCO:B0067138 name: IQEC1_HUMAN-Phosphothreonine362 def: "Protein IQEC1_HUMAN with the residue 362 substituted with Phosphothreonine" [UniProtKB:Q6DN90] xref: UniProtKB:Q6DN90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056728 ! IQEC1_HUMAN [Term] id: CCO:B0067139 name: IQEC1_HUMAN-Phosphoserine512 def: "Protein IQEC1_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q6DN90] xref: UniProtKB:Q6DN90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056728 ! IQEC1_HUMAN [Term] id: CCO:B0067140 name: IQEC1_HUMAN-Phosphoserine515 def: "Protein IQEC1_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:Q6DN90] comment: By similarity xref: UniProtKB:Q6DN90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056728 ! IQEC1_HUMAN [Term] id: CCO:B0067141 name: IQEC2_HUMAN-Phosphoserine82 def: "Protein IQEC2_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q5JU85] comment: By similarity xref: UniProtKB:Q5JU85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056485 ! IQEC2_HUMAN [Term] id: CCO:B0067142 name: IQEC2_HUMAN-Phosphotyrosine89 def: "Protein IQEC2_HUMAN with the residue 89 substituted with Phosphotyrosine" [UniProtKB:Q5JU85] comment: By similarity xref: UniProtKB:Q5JU85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056485 ! IQEC2_HUMAN [Term] id: CCO:B0067143 name: IQEC2_HUMAN-Phosphotyrosine611 def: "Protein IQEC2_HUMAN with the residue 611 substituted with Phosphotyrosine" [UniProtKB:Q5JU85] comment: By similarity xref: UniProtKB:Q5JU85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056485 ! IQEC2_HUMAN [Term] id: CCO:B0067144 name: IQEC2_HUMAN-Phosphotyrosine923 def: "Protein IQEC2_HUMAN with the residue 923 substituted with Phosphotyrosine" [UniProtKB:Q5JU85] comment: By similarity xref: UniProtKB:Q5JU85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056485 ! IQEC2_HUMAN [Term] id: CCO:B0067145 name: IQEC2_HUMAN-Phosphotyrosine1119 def: "Protein IQEC2_HUMAN with the residue 1119 substituted with Phosphotyrosine" [UniProtKB:Q5JU85] comment: By similarity xref: UniProtKB:Q5JU85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056485 ! IQEC2_HUMAN [Term] id: CCO:B0067146 name: IQEC3_HUMAN-Phosphothreonine649 def: "Protein IQEC3_HUMAN with the residue 649 substituted with Phosphothreonine" [UniProtKB:Q9UPP2] comment: By similarity xref: UniProtKB:Q9UPP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059262 ! IQEC3_HUMAN [Term] id: CCO:B0067147 name: IQEC3_HUMAN-Phosphoserine1019 def: "Protein IQEC3_HUMAN with the residue 1019 substituted with Phosphoserine" [UniProtKB:Q9UPP2] comment: By similarity xref: UniProtKB:Q9UPP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059262 ! IQEC3_HUMAN [Term] id: CCO:B0067148 name: IQGA1_HUMAN-Phosphotyrosine654 def: "Protein IQGA1_HUMAN with the residue 654 substituted with Phosphotyrosine" [UniProtKB:P46940] xref: UniProtKB:P46940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:B0067149 name: IQGA1_HUMAN-Phosphotyrosine1510 def: "Protein IQGA1_HUMAN with the residue 1510 substituted with Phosphotyrosine" [UniProtKB:P46940] xref: UniProtKB:P46940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:B0067150 name: IQGA3_HUMAN-Phosphoserine1424 def: "Protein IQGA3_HUMAN with the residue 1424 substituted with Phosphoserine" [UniProtKB:Q86VI3] xref: UniProtKB:Q86VI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001404 ! Ras GTPase activator activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0018395 ! IQGA3_HUMAN [Term] id: CCO:B0067151 name: IQGA3_HUMAN-Phosphotyrosine1537 def: "Protein IQGA3_HUMAN with the residue 1537 substituted with Phosphotyrosine" [UniProtKB:Q86VI3] xref: UniProtKB:Q86VI3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018395 ! IQGA3_HUMAN [Term] id: CCO:B0067152 name: IRAK1_HUMAN-Phosphoserine568 def: "Protein IRAK1_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:P51617] xref: UniProtKB:P51617 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001070 ! NF-kappaB-inducing kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001948 ! interleukin-1 receptor complex relationship: transformation_of CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:B0067153 name: IRK2_HUMAN-Phosphotyrosine337 def: "Protein IRK2_HUMAN with the residue 337 substituted with Phosphotyrosine" [UniProtKB:P63252] xref: UniProtKB:P63252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030995 ! IRK2_HUMAN [Term] id: CCO:B0067154 name: IRS4_HUMAN-Phosphotyrosine1038 def: "Protein IRS4_HUMAN with the residue 1038 substituted with Phosphotyrosine" [UniProtKB:O14654] xref: UniProtKB:O14654 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0051815 ! IRS4_HUMAN [Term] id: CCO:B0067155 name: ISL1_HUMAN-Phosphothreonine182 def: "Protein ISL1_HUMAN with the residue 182 substituted with Phosphothreonine" [UniProtKB:P61371] xref: UniProtKB:P61371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055610 ! ISL1_HUMAN [Term] id: CCO:B0067156 name: ISL2_HUMAN-Phosphoserine154 def: "Protein ISL2_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q96A47] xref: UniProtKB:Q96A47 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058146 ! ISL2_HUMAN [Term] id: CCO:B0067157 name: ISL2_HUMAN-Phosphoserine157 def: "Protein ISL2_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:Q96A47] xref: UniProtKB:Q96A47 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058146 ! ISL2_HUMAN [Term] id: CCO:B0067158 name: ITA2B_HUMAN-acid891 def: "Protein ITA2B_HUMAN with the residue 891 substituted with acid" [UniProtKB:P08514] comment: in light chain form 1; xref: UniProtKB:P08514 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:B0067159 name: ITA4_HUMAN-Phosphoserine1021 def: "Protein ITA4_HUMAN with the residue 1021 substituted with Phosphoserine" [UniProtKB:P13612] xref: UniProtKB:P13612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000544 ! integrin complex relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055015 ! ITA4_HUMAN [Term] id: CCO:B0067160 name: ITCH_HUMAN-Phosphotyrosine420 def: "Protein ITCH_HUMAN with the residue 420 substituted with Phosphotyrosine" [UniProtKB:Q96J02] xref: UniProtKB:Q96J02 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058235 ! ITCH_HUMAN [Term] id: CCO:B0067161 name: ITK_HUMAN-Phosphotyrosine180 def: "Protein ITK_HUMAN with the residue 180 substituted with Phosphotyrosine" [UniProtKB:Q08881] comment: by autocatalysis; xref: UniProtKB:Q08881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055796 ! ITK_HUMAN [Term] id: CCO:B0067162 name: ITK_HUMAN-Phosphotyrosine512 def: "Protein ITK_HUMAN with the residue 512 substituted with Phosphotyrosine" [UniProtKB:Q08881] comment: by autocatalysis; xref: UniProtKB:Q08881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055796 ! ITK_HUMAN [Term] id: CCO:B0067163 name: ITK_HUMAN-Phosphoserine565 def: "Protein ITK_HUMAN with the residue 565 substituted with Phosphoserine" [UniProtKB:Q08881] xref: UniProtKB:Q08881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055796 ! ITK_HUMAN [Term] id: CCO:B0067164 name: ITM2C_HUMAN-Phosphothreonine37 def: "Protein ITM2C_HUMAN with the residue 37 substituted with Phosphothreonine" [UniProtKB:Q9NQX7] comment: By similarity xref: UniProtKB:Q9NQX7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062773 ! ITM2C_HUMAN [Term] id: CCO:B0067165 name: ITPR1_HUMAN-Phosphotyrosine482 def: "Protein ITPR1_HUMAN with the residue 482 substituted with Phosphotyrosine" [UniProtKB:Q14643] comment: Potential xref: UniProtKB:Q14643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056007 ! ITPR1_HUMAN [Term] id: CCO:B0067166 name: ITPR1_HUMAN-Phosphoserine1598 def: "Protein ITPR1_HUMAN with the residue 1598 substituted with Phosphoserine" [UniProtKB:Q14643] xref: UniProtKB:Q14643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001496 ! inositol 1,4,5-triphosphate-sensitive calcium-release channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001708 ! inositol-1,4,5-triphosphate receptor activity relationship: has_function CCO:F0002565 ! calcium ion transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001132 ! platelet dense tubular network membrane relationship: transformation_of CCO:B0056007 ! ITPR1_HUMAN [Term] id: CCO:B0067167 name: ITPR1_HUMAN-Phosphoserine1764 def: "Protein ITPR1_HUMAN with the residue 1764 substituted with Phosphoserine" [UniProtKB:Q14643] xref: UniProtKB:Q14643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056007 ! ITPR1_HUMAN [Term] id: CCO:B0067168 name: ITPR1_HUMAN-Phosphotyrosine2664 def: "Protein ITPR1_HUMAN with the residue 2664 substituted with Phosphotyrosine" [UniProtKB:Q14643] comment: Potential xref: UniProtKB:Q14643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056007 ! ITPR1_HUMAN [Term] id: CCO:B0067169 name: ITPR2_HUMAN-Phosphoserine1160 def: "Protein ITPR2_HUMAN with the residue 1160 substituted with Phosphoserine" [UniProtKB:Q14571] xref: UniProtKB:Q14571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055994 ! ITPR2_HUMAN [Term] id: CCO:B0067170 name: ITPR2_HUMAN-Phosphotyrosine2607 def: "Protein ITPR2_HUMAN with the residue 2607 substituted with Phosphotyrosine" [UniProtKB:Q14571] comment: Potential xref: UniProtKB:Q14571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001496 ! inositol 1,4,5-triphosphate-sensitive calcium-release channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001708 ! inositol-1,4,5-triphosphate receptor activity relationship: has_function CCO:F0002565 ! calcium ion transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055994 ! ITPR2_HUMAN [Term] id: CCO:B0067171 name: ITPR3_HUMAN-Phosphoserine916 def: "Protein ITPR3_HUMAN with the residue 916 substituted with Phosphoserine" [UniProtKB:Q14573] xref: UniProtKB:Q14573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055995 ! ITPR3_HUMAN [Term] id: CCO:B0067172 name: ITPR3_HUMAN-Phosphoserine934 def: "Protein ITPR3_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:Q14573] xref: UniProtKB:Q14573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055995 ! ITPR3_HUMAN [Term] id: CCO:B0067173 name: ITPR3_HUMAN-Phosphoserine1832 def: "Protein ITPR3_HUMAN with the residue 1832 substituted with Phosphoserine" [UniProtKB:Q14573] xref: UniProtKB:Q14573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001496 ! inositol 1,4,5-triphosphate-sensitive calcium-release channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001708 ! inositol-1,4,5-triphosphate receptor activity relationship: has_function CCO:F0002565 ! calcium ion transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000460 ! brush border relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055995 ! ITPR3_HUMAN [Term] id: CCO:B0067174 name: ITPR3_HUMAN-Phosphotyrosine2583 def: "Protein ITPR3_HUMAN with the residue 2583 substituted with Phosphotyrosine" [UniProtKB:Q14573] comment: Potential xref: UniProtKB:Q14573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055995 ! ITPR3_HUMAN [Term] id: CCO:B0067175 name: ITPR3_HUMAN-Phosphoserine2670 def: "Protein ITPR3_HUMAN with the residue 2670 substituted with Phosphoserine" [UniProtKB:Q14573] xref: UniProtKB:Q14573 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055995 ! ITPR3_HUMAN [Term] id: CCO:B0067176 name: ITSN2_HUMAN-Phosphoserine883 def: "Protein ITSN2_HUMAN with the residue 883 substituted with Phosphoserine" [UniProtKB:Q9NZM3] xref: UniProtKB:Q9NZM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:B0067177 name: ITSN2_HUMAN-Phosphoserine888 def: "Protein ITSN2_HUMAN with the residue 888 substituted with Phosphoserine" [UniProtKB:Q9NZM3] xref: UniProtKB:Q9NZM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:B0067178 name: JAD1A_HUMAN-Phosphoserine1111 def: "Protein JAD1A_HUMAN with the residue 1111 substituted with Phosphoserine" [UniProtKB:P29375] xref: UniProtKB:P29375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055213 ! JAD1A_HUMAN [Term] id: CCO:B0067179 name: JAD1A_HUMAN-Phosphoserine1331 def: "Protein JAD1A_HUMAN with the residue 1331 substituted with Phosphoserine" [UniProtKB:P29375] xref: UniProtKB:P29375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000901 ! cyclin-dependent protein kinase activating kinase holoenzyme complex relationship: transformation_of CCO:B0055213 ! JAD1A_HUMAN [Term] id: CCO:B0067180 name: JAD1A_HUMAN-Phosphoserine1598 def: "Protein JAD1A_HUMAN with the residue 1598 substituted with Phosphoserine" [UniProtKB:P29375] xref: UniProtKB:P29375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055213 ! JAD1A_HUMAN [Term] id: CCO:B0067181 name: JAD1A_HUMAN-Phosphoserine1603 def: "Protein JAD1A_HUMAN with the residue 1603 substituted with Phosphoserine" [UniProtKB:P29375] xref: UniProtKB:P29375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055213 ! JAD1A_HUMAN [Term] id: CCO:B0067182 name: JAD1A_HUMAN-Phosphoserine1666 def: "Protein JAD1A_HUMAN with the residue 1666 substituted with Phosphoserine" [UniProtKB:P29375] xref: UniProtKB:P29375 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055213 ! JAD1A_HUMAN [Term] id: CCO:B0067183 name: JAD1B_HUMAN-Phosphoserine1383 def: "Protein JAD1B_HUMAN with the residue 1383 substituted with Phosphoserine" [UniProtKB:Q9UGL1] xref: UniProtKB:Q9UGL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059124 ! JAD1B_HUMAN [Term] id: CCO:B0067184 name: JAD1B_HUMAN-Phosphoserine1384 def: "Protein JAD1B_HUMAN with the residue 1384 substituted with Phosphoserine" [UniProtKB:Q9UGL1] xref: UniProtKB:Q9UGL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059124 ! JAD1B_HUMAN [Term] id: CCO:B0067185 name: JAD1B_HUMAN-Phosphoserine1405 def: "Protein JAD1B_HUMAN with the residue 1405 substituted with Phosphoserine" [UniProtKB:Q9UGL1] xref: UniProtKB:Q9UGL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059124 ! JAD1B_HUMAN [Term] id: CCO:B0067186 name: JAD1C_HUMAN-Phosphoserine317 def: "Protein JAD1C_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:P41229] xref: UniProtKB:P41229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055337 ! JAD1C_HUMAN [Term] id: CCO:B0067187 name: JAD1C_HUMAN-Phosphoserine1359 def: "Protein JAD1C_HUMAN with the residue 1359 substituted with Phosphoserine" [UniProtKB:P41229] xref: UniProtKB:P41229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055337 ! JAD1C_HUMAN [Term] id: CCO:B0067188 name: JADE1_HUMAN-Phosphoserine8 def: "Protein JADE1_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q6IE81] xref: UniProtKB:Q6IE81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056759 ! JADE1_HUMAN [Term] id: CCO:B0067189 name: JADE1_HUMAN-Phosphoserine9 def: "Protein JADE1_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:Q6IE81] xref: UniProtKB:Q6IE81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056759 ! JADE1_HUMAN [Term] id: CCO:B0067190 name: JADE1_HUMAN-Phosphoserine10 def: "Protein JADE1_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:Q6IE81] xref: UniProtKB:Q6IE81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056759 ! JADE1_HUMAN [Term] id: CCO:B0067191 name: JADE1_HUMAN-Phosphoserine13 def: "Protein JADE1_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:Q6IE81] xref: UniProtKB:Q6IE81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056759 ! JADE1_HUMAN [Term] id: CCO:B0067192 name: JADE1_HUMAN-Phosphoserine89 def: "Protein JADE1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q6IE81] xref: UniProtKB:Q6IE81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056759 ! JADE1_HUMAN [Term] id: CCO:B0067193 name: JADE1_HUMAN-Phosphothreonine92 def: "Protein JADE1_HUMAN with the residue 92 substituted with Phosphothreonine" [UniProtKB:Q6IE81] xref: UniProtKB:Q6IE81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056759 ! JADE1_HUMAN [Term] id: CCO:B0067194 name: JAK2_HUMAN-Phosphotyrosine570 def: "Protein JAK2_HUMAN with the residue 570 substituted with Phosphotyrosine" [UniProtKB:O60674] comment: By similarity xref: UniProtKB:O60674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001414 ! JAK2_HUMAN [Term] id: CCO:B0067195 name: JAK2_HUMAN-Phosphotyrosine813 def: "Protein JAK2_HUMAN with the residue 813 substituted with Phosphotyrosine" [UniProtKB:O60674] comment: By similarity xref: UniProtKB:O60674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001414 ! JAK2_HUMAN [Term] id: CCO:B0067196 name: JAK2_HUMAN-Phosphotyrosine1008 def: "Protein JAK2_HUMAN with the residue 1008 substituted with Phosphotyrosine" [UniProtKB:O60674] xref: UniProtKB:O60674 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001414 ! JAK2_HUMAN [Term] id: CCO:B0067197 name: JDP2_HUMAN-Phosphothreonine148 def: "Protein JDP2_HUMAN with the residue 148 substituted with Phosphothreonine" [UniProtKB:Q8WYK2] comment: by MAPK8; xref: UniProtKB:Q8WYK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058043 ! JDP2_HUMAN [Term] id: CCO:B0067198 name: JHD1A_HUMAN-Phosphoserine390 def: "Protein JHD1A_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0067199 name: JHD1A_HUMAN-Phosphoserine394 def: "Protein JHD1A_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0067200 name: JHD1A_HUMAN-Phosphoserine692 def: "Protein JHD1A_HUMAN with the residue 692 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0067201 name: JHD1A_HUMAN-Phosphoserine721 def: "Protein JHD1A_HUMAN with the residue 721 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0067202 name: JHD1A_HUMAN-Phosphoserine832 def: "Protein JHD1A_HUMAN with the residue 832 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0067203 name: JHD1A_HUMAN-Phosphothreonine844 def: "Protein JHD1A_HUMAN with the residue 844 substituted with Phosphothreonine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0067204 name: JHD1A_HUMAN-Phosphoserine869 def: "Protein JHD1A_HUMAN with the residue 869 substituted with Phosphoserine" [UniProtKB:Q9Y2K7] xref: UniProtKB:Q9Y2K7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:B0067205 name: JHD2B_HUMAN-Phosphoserine291 def: "Protein JHD2B_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:Q7LBC6] xref: UniProtKB:Q7LBC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057122 ! JHD2B_HUMAN [Term] id: CCO:B0067206 name: JHD2B_HUMAN-Phosphoserine773 def: "Protein JHD2B_HUMAN with the residue 773 substituted with Phosphoserine" [UniProtKB:Q7LBC6] xref: UniProtKB:Q7LBC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057122 ! JHD2B_HUMAN [Term] id: CCO:B0067207 name: JHD2B_HUMAN-Phosphoserine779 def: "Protein JHD2B_HUMAN with the residue 779 substituted with Phosphoserine" [UniProtKB:Q7LBC6] xref: UniProtKB:Q7LBC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057122 ! JHD2B_HUMAN [Term] id: CCO:B0067208 name: JHD2B_HUMAN-Phosphoserine798 def: "Protein JHD2B_HUMAN with the residue 798 substituted with Phosphoserine" [UniProtKB:Q7LBC6] xref: UniProtKB:Q7LBC6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057122 ! JHD2B_HUMAN [Term] id: CCO:B0067209 name: JHD2C_HUMAN-Phosphoserine373 def: "Protein JHD2C_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:Q15652] xref: UniProtKB:Q15652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056093 ! JHD2C_HUMAN [Term] id: CCO:B0067210 name: JHD2C_HUMAN-Phosphoserine376 def: "Protein JHD2C_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q15652] xref: UniProtKB:Q15652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056093 ! JHD2C_HUMAN [Term] id: CCO:B0067211 name: JHD2C_HUMAN-Phosphoserine379 def: "Protein JHD2C_HUMAN with the residue 379 substituted with Phosphoserine" [UniProtKB:Q15652] xref: UniProtKB:Q15652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056093 ! JHD2C_HUMAN [Term] id: CCO:B0067212 name: JHD2C_HUMAN-Phosphoserine430 def: "Protein JHD2C_HUMAN with the residue 430 substituted with Phosphoserine" [UniProtKB:Q15652] xref: UniProtKB:Q15652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056093 ! JHD2C_HUMAN [Term] id: CCO:B0067213 name: JHD2C_HUMAN-Phosphoserine638 def: "Protein JHD2C_HUMAN with the residue 638 substituted with Phosphoserine" [UniProtKB:Q15652] xref: UniProtKB:Q15652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056093 ! JHD2C_HUMAN [Term] id: CCO:B0067214 name: JHD2C_HUMAN-Phosphoserine641 def: "Protein JHD2C_HUMAN with the residue 641 substituted with Phosphoserine" [UniProtKB:Q15652] xref: UniProtKB:Q15652 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056093 ! JHD2C_HUMAN [Term] id: CCO:B0067215 name: JHD3A_HUMAN-Phosphotyrosine547 def: "Protein JHD3A_HUMAN with the residue 547 substituted with Phosphotyrosine" [UniProtKB:O75164] xref: UniProtKB:O75164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008199 ! histone demethylase activity (H3-K36 specific) relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054610 ! JHD3A_HUMAN [Term] id: CCO:B0067216 name: JHD3B_HUMAN-Phosphothreonine305 def: "Protein JHD3B_HUMAN with the residue 305 substituted with Phosphothreonine" [UniProtKB:O94953] comment: By similarity xref: UniProtKB:O94953 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054713 ! JHD3B_HUMAN [Term] id: CCO:B0067217 name: JHD3B_HUMAN-Phosphoserine566 def: "Protein JHD3B_HUMAN with the residue 566 substituted with Phosphoserine" [UniProtKB:O94953] xref: UniProtKB:O94953 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054713 ! JHD3B_HUMAN [Term] id: CCO:B0067218 name: JHD3B_HUMAN-Phosphoserine622 def: "Protein JHD3B_HUMAN with the residue 622 substituted with Phosphoserine" [UniProtKB:O94953] xref: UniProtKB:O94953 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054713 ! JHD3B_HUMAN [Term] id: CCO:B0067219 name: JIP1_HUMAN-Phosphothreonine103 def: "Protein JIP1_HUMAN with the residue 103 substituted with Phosphothreonine" [UniProtKB:Q9UQF2] comment: by MAPK8, MAPK9 and MAPK10; xref: UniProtKB:Q9UQF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001384 ! MAP-kinase scaffold activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004206 ! kinesin binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059280 ! JIP1_HUMAN [Term] id: CCO:B0067220 name: JIP1_HUMAN-Phosphothreonine205 def: "Protein JIP1_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:Q9UQF2] comment: by MAPK8, MAPK9 and MAPK10; xref: UniProtKB:Q9UQF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059280 ! JIP1_HUMAN [Term] id: CCO:B0067221 name: JMY_HUMAN-Phosphoserine974 def: "Protein JMY_HUMAN with the residue 974 substituted with Phosphoserine" [UniProtKB:Q8N9B5] xref: UniProtKB:Q8N9B5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040022 ! JMY_HUMAN [Term] id: CCO:B0067222 name: JPH1_HUMAN-Phosphoserine157 def: "Protein JPH1_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067223 name: JPH1_HUMAN-Phosphoserine216 def: "Protein JPH1_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067224 name: JPH1_HUMAN-Phosphoserine220 def: "Protein JPH1_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000802 ! sarcoplasmic reticulum relationship: located_in CCO:C0000934 ! Z disc relationship: located_in CCO:C0001001 ! junctional membrane complex relationship: located_in CCO:C0001507 ! sarcoplasmic reticulum membrane relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067225 name: JPH1_HUMAN-Phosphothreonine448 def: "Protein JPH1_HUMAN with the residue 448 substituted with Phosphothreonine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067226 name: JPH1_HUMAN-Phosphoserine452 def: "Protein JPH1_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067227 name: JPH1_HUMAN-Phosphothreonine461 def: "Protein JPH1_HUMAN with the residue 461 substituted with Phosphothreonine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067228 name: JPH1_HUMAN-Phosphoserine465 def: "Protein JPH1_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067229 name: JPH1_HUMAN-Phosphoserine469 def: "Protein JPH1_HUMAN with the residue 469 substituted with Phosphoserine" [UniProtKB:Q9HDC5] xref: UniProtKB:Q9HDC5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:B0067230 name: JUND_HUMAN-Phosphoserine255 def: "Protein JUND_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:P17535] xref: UniProtKB:P17535 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055089 ! JUND_HUMAN [Term] id: CCO:B0067231 name: JUND_HUMAN-Phosphoserine259 def: "Protein JUND_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:P17535] xref: UniProtKB:P17535 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055089 ! JUND_HUMAN [Term] id: CCO:B0067232 name: K1219_HUMAN-Phosphoserine417 def: "Protein K1219_HUMAN with the residue 417 substituted with Phosphoserine" [UniProtKB:Q86X10] xref: UniProtKB:Q86X10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057283 ! K1219_HUMAN [Term] id: CCO:B0067233 name: K1219_HUMAN-Phosphoserine421 def: "Protein K1219_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q86X10] xref: UniProtKB:Q86X10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057283 ! K1219_HUMAN [Term] id: CCO:B0067234 name: K1219_HUMAN-Phosphoserine720 def: "Protein K1219_HUMAN with the residue 720 substituted with Phosphoserine" [UniProtKB:Q86X10] comment: By similarity xref: UniProtKB:Q86X10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057283 ! K1219_HUMAN [Term] id: CCO:B0067235 name: K1267_HUMAN-Phosphoserine249 def: "Protein K1267_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q7Z3B3] xref: UniProtKB:Q7Z3B3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005600 ! K1267_HUMAN [Term] id: CCO:B0067236 name: K1688_HUMAN-Phosphoserine173 def: "Protein K1688_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q9C0H5] xref: UniProtKB:Q9C0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058620 ! K1688_HUMAN [Term] id: CCO:B0067237 name: K1688_HUMAN-Phosphoserine248 def: "Protein K1688_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:Q9C0H5] xref: UniProtKB:Q9C0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058620 ! K1688_HUMAN [Term] id: CCO:B0067238 name: K1688_HUMAN-Phosphoserine406 def: "Protein K1688_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:Q9C0H5] xref: UniProtKB:Q9C0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0058620 ! K1688_HUMAN [Term] id: CCO:B0067239 name: K1688_HUMAN-Phosphoserine407 def: "Protein K1688_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q9C0H5] xref: UniProtKB:Q9C0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058620 ! K1688_HUMAN [Term] id: CCO:B0067240 name: K1688_HUMAN-Phosphoserine604 def: "Protein K1688_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:Q9C0H5] xref: UniProtKB:Q9C0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058620 ! K1688_HUMAN [Term] id: CCO:B0067241 name: K1C18_HUMAN-Phosphotyrosine13 def: "Protein K1C18_HUMAN with the residue 13 substituted with Phosphotyrosine" [UniProtKB:P05783] xref: UniProtKB:P05783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001489 ! K1C18_HUMAN [Term] id: CCO:B0067242 name: K2018_HUMAN-Phosphoserine1769 def: "Protein K2018_HUMAN with the residue 1769 substituted with Phosphoserine" [UniProtKB:Q68DE3] xref: UniProtKB:Q68DE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056702 ! K2018_HUMAN [Term] id: CCO:B0067243 name: K2018_HUMAN-Phosphoserine1775 def: "Protein K2018_HUMAN with the residue 1775 substituted with Phosphoserine" [UniProtKB:Q68DE3] xref: UniProtKB:Q68DE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000954 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056702 ! K2018_HUMAN [Term] id: CCO:B0067244 name: K2C5_HUMAN-Phosphotyrosine60 def: "Protein K2C5_HUMAN with the residue 60 substituted with Phosphotyrosine" [UniProtKB:P13647] xref: UniProtKB:P13647 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005811 ! K2C5_HUMAN [Term] id: CCO:B0067245 name: K2C5_HUMAN-Phosphotyrosine66 def: "Protein K2C5_HUMAN with the residue 66 substituted with Phosphotyrosine" [UniProtKB:P13647] xref: UniProtKB:P13647 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005811 ! K2C5_HUMAN [Term] id: CCO:B0067246 name: K2C7_HUMAN-N-acetylserine2 def: "Protein K2C7_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P08729] xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0067247 name: K2C7_HUMAN-Phosphotyrosine205 def: "Protein K2C7_HUMAN with the residue 205 substituted with Phosphotyrosine" [UniProtKB:P08729] xref: UniProtKB:P08729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:B0067248 name: K2C8_HUMAN-Phosphotyrosine204 def: "Protein K2C8_HUMAN with the residue 204 substituted with Phosphotyrosine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0067249 name: K2C8_HUMAN-Phosphotyrosine267 def: "Protein K2C8_HUMAN with the residue 267 substituted with Phosphotyrosine" [UniProtKB:P05787] xref: UniProtKB:P05787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:B0067250 name: KAISO_HUMAN-Phosphotyrosine442 def: "Protein KAISO_HUMAN with the residue 442 substituted with Phosphotyrosine" [UniProtKB:Q86T24] xref: UniProtKB:Q86T24 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057236 ! KAISO_HUMAN [Term] id: CCO:B0067251 name: KALRN_HUMAN-Phosphoserine1750 def: "Protein KALRN_HUMAN with the residue 1750 substituted with Phosphoserine" [UniProtKB:O60229] xref: UniProtKB:O60229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: transformation_of CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:B0067252 name: KALRN_HUMAN-Phosphoserine1753 def: "Protein KALRN_HUMAN with the residue 1753 substituted with Phosphoserine" [UniProtKB:O60229] xref: UniProtKB:O60229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:B0067253 name: KALRN_HUMAN-Phosphoserine1756 def: "Protein KALRN_HUMAN with the residue 1756 substituted with Phosphoserine" [UniProtKB:O60229] xref: UniProtKB:O60229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:B0067254 name: KALRN_HUMAN-Phosphoserine1773 def: "Protein KALRN_HUMAN with the residue 1773 substituted with Phosphoserine" [UniProtKB:O60229] xref: UniProtKB:O60229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:B0067255 name: KALRN_HUMAN-Phosphoserine1799 def: "Protein KALRN_HUMAN with the residue 1799 substituted with Phosphoserine" [UniProtKB:O60229] xref: UniProtKB:O60229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:B0067256 name: KALRN_HUMAN-Phosphoserine1817 def: "Protein KALRN_HUMAN with the residue 1817 substituted with Phosphoserine" [UniProtKB:O60229] xref: UniProtKB:O60229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:B0067257 name: KALRN_HUMAN-Phosphoserine2261 def: "Protein KALRN_HUMAN with the residue 2261 substituted with Phosphoserine" [UniProtKB:O60229] xref: UniProtKB:O60229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:B0067258 name: KAP1_HUMAN-Phosphoserine77 def: "Protein KAP1_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P31321] xref: UniProtKB:P31321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021337 ! KAP1_HUMAN [Term] id: CCO:B0067259 name: KAP1_HUMAN-Phosphoserine83 def: "Protein KAP1_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:P31321] xref: UniProtKB:P31321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021337 ! KAP1_HUMAN [Term] id: CCO:B0067260 name: KC1A_HUMAN-Phosphothreonine321 def: "Protein KC1A_HUMAN with the residue 321 substituted with Phosphothreonine" [UniProtKB:P48729] xref: UniProtKB:P48729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055410 ! KC1A_HUMAN [Term] id: CCO:B0067261 name: KC1D_HUMAN-Phosphothreonine347 def: "Protein KC1D_HUMAN with the residue 347 substituted with Phosphothreonine" [UniProtKB:P48730] xref: UniProtKB:P48730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001051 ! casein kinase I activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0017481 ! KC1D_HUMAN [Term] id: CCO:B0067262 name: KC1D_HUMAN-Phosphothreonine349 def: "Protein KC1D_HUMAN with the residue 349 substituted with Phosphothreonine" [UniProtKB:P48730] xref: UniProtKB:P48730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017481 ! KC1D_HUMAN [Term] id: CCO:B0067263 name: KC1D_HUMAN-Phosphoserine384 def: "Protein KC1D_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:P48730] xref: UniProtKB:P48730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017481 ! KC1D_HUMAN [Term] id: CCO:B0067264 name: KCAB2_HUMAN-Phosphoserine9 def: "Protein KCAB2_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:Q13303] comment: By similarity xref: UniProtKB:Q13303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063325 ! KCAB2_HUMAN [Term] id: CCO:B0067265 name: KCAB2_HUMAN-Phosphoserine20 def: "Protein KCAB2_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q13303] comment: By similarity xref: UniProtKB:Q13303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063325 ! KCAB2_HUMAN [Term] id: CCO:B0067266 name: KCAB2_HUMAN-Phosphotyrosine25 def: "Protein KCAB2_HUMAN with the residue 25 substituted with Phosphotyrosine" [UniProtKB:Q13303] xref: UniProtKB:Q13303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063325 ! KCAB2_HUMAN [Term] id: CCO:B0067267 name: KCAB2_HUMAN-Phosphotyrosine360 def: "Protein KCAB2_HUMAN with the residue 360 substituted with Phosphotyrosine" [UniProtKB:Q13303] comment: By similarity xref: UniProtKB:Q13303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0002867 ! potassium channel regulator activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063325 ! KCAB2_HUMAN [Term] id: CCO:B0067268 name: KCC2B_HUMAN-Phosphotyrosine17 def: "Protein KCC2B_HUMAN with the residue 17 substituted with Phosphotyrosine" [UniProtKB:Q13554] comment: By similarity xref: UniProtKB:Q13554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016545 ! KCC2B_HUMAN [Term] id: CCO:B0067269 name: KCC2B_HUMAN-Phosphothreonine287 def: "Protein KCC2B_HUMAN with the residue 287 substituted with Phosphothreonine" [UniProtKB:Q13554] comment: By similarity xref: UniProtKB:Q13554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016545 ! KCC2B_HUMAN [Term] id: CCO:B0067270 name: KCC2B_HUMAN-Phosphoserine315 def: "Protein KCC2B_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q13554] comment: By similarity xref: UniProtKB:Q13554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016545 ! KCC2B_HUMAN [Term] id: CCO:B0067271 name: KCC2B_HUMAN-Phosphoserine367 def: "Protein KCC2B_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q13554] comment: By similarity xref: UniProtKB:Q13554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016545 ! KCC2B_HUMAN [Term] id: CCO:B0067272 name: KCC2B_HUMAN-Phosphoserine397 def: "Protein KCC2B_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q13554] comment: By similarity xref: UniProtKB:Q13554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016545 ! KCC2B_HUMAN [Term] id: CCO:B0067273 name: KCC2D_HUMAN-Phosphotyrosine231 def: "Protein KCC2D_HUMAN with the residue 231 substituted with Phosphotyrosine" [UniProtKB:Q13557] comment: By similarity xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067274 name: KCC2D_HUMAN-Phosphothreonine287 def: "Protein KCC2D_HUMAN with the residue 287 substituted with Phosphothreonine" [UniProtKB:Q13557] comment: By similarity xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067275 name: KCC2D_HUMAN-Phosphoserine315 def: "Protein KCC2D_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q13557] xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000503 ! calcium- and calmodulin-dependent protein kinase complex relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067276 name: KCC2D_HUMAN-Phosphoserine319 def: "Protein KCC2D_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q13557] xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067277 name: KCC2D_HUMAN-Phosphoserine330 def: "Protein KCC2D_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q13557] xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067278 name: KCC2D_HUMAN-Phosphothreonine331 def: "Protein KCC2D_HUMAN with the residue 331 substituted with Phosphothreonine" [UniProtKB:Q13557] xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067279 name: KCC2D_HUMAN-Phosphoserine333 def: "Protein KCC2D_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q13557] xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067280 name: KCC2D_HUMAN-Phosphothreonine337 def: "Protein KCC2D_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:Q13557] xref: UniProtKB:Q13557 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016505 ! KCC2D_HUMAN [Term] id: CCO:B0067281 name: KCD15_HUMAN-Phosphoserine31 def: "Protein KCD15_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q96SI1] xref: UniProtKB:Q96SI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063417 ! KCD15_HUMAN [Term] id: CCO:B0067282 name: KCD15_HUMAN-Phosphoserine35 def: "Protein KCD15_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q96SI1] xref: UniProtKB:Q96SI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063417 ! KCD15_HUMAN [Term] id: CCO:B0067283 name: KCD15_HUMAN-Phosphoserine38 def: "Protein KCD15_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:Q96SI1] xref: UniProtKB:Q96SI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063417 ! KCD15_HUMAN [Term] id: CCO:B0067284 name: KCIP2_HUMAN-Phosphothreonine103 def: "Protein KCIP2_HUMAN with the residue 103 substituted with Phosphothreonine" [UniProtKB:Q9NS61] xref: UniProtKB:Q9NS61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020223 ! KCIP2_HUMAN [Term] id: CCO:B0067285 name: KCIP2_HUMAN-Phosphotyrosine111 def: "Protein KCIP2_HUMAN with the residue 111 substituted with Phosphotyrosine" [UniProtKB:Q9NS61] xref: UniProtKB:Q9NS61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001518 ! A-type (transient outward) potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0006275 ! ER retention sequence binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0020223 ! KCIP2_HUMAN [Term] id: CCO:B0067286 name: KCMA1_HUMAN-Phosphoserine569 def: "Protein KCMA1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q12791] xref: UniProtKB:Q12791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:B0067287 name: KCMA1_HUMAN-Phosphothreonine763 def: "Protein KCMA1_HUMAN with the residue 763 substituted with Phosphothreonine" [UniProtKB:Q12791] comment: By similarity xref: UniProtKB:Q12791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:B0067288 name: KCMA1_HUMAN-Phosphoserine765 def: "Protein KCMA1_HUMAN with the residue 765 substituted with Phosphoserine" [UniProtKB:Q12791] comment: By similarity xref: UniProtKB:Q12791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:B0067289 name: KCMA1_HUMAN-Phosphoserine977 def: "Protein KCMA1_HUMAN with the residue 977 substituted with Phosphoserine" [UniProtKB:Q12791] comment: By similarity xref: UniProtKB:Q12791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:B0067290 name: KCMA1_HUMAN-Phosphoserine978 def: "Protein KCMA1_HUMAN with the residue 978 substituted with Phosphoserine" [UniProtKB:Q12791] comment: By similarity xref: UniProtKB:Q12791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:B0067291 name: KCMA1_HUMAN-Phosphotyrosine1086 def: "Protein KCMA1_HUMAN with the residue 1086 substituted with Phosphotyrosine" [UniProtKB:Q12791] xref: UniProtKB:Q12791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002726 ! calcium-activated potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008239 ! large conductance calcium-activated potassium channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001727 ! terminal button relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:B0067292 name: KCMA1_HUMAN-Phosphothreonine1088 def: "Protein KCMA1_HUMAN with the residue 1088 substituted with Phosphothreonine" [UniProtKB:Q12791] comment: By similarity xref: UniProtKB:Q12791 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:B0067293 name: KCNH7_HUMAN-Phosphoserine349 def: "Protein KCNH7_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q9NS40] xref: UniProtKB:Q9NS40 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058908 ! KCNH7_HUMAN [Term] id: CCO:B0067294 name: KCNH7_HUMAN-Phosphoserine350 def: "Protein KCNH7_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:Q9NS40] xref: UniProtKB:Q9NS40 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058908 ! KCNH7_HUMAN [Term] id: CCO:B0067295 name: KCNH7_HUMAN-Phosphoserine353 def: "Protein KCNH7_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q9NS40] xref: UniProtKB:Q9NS40 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001512 ! voltage-gated ion channel activity relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001526 ! potassium channel activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058908 ! KCNH7_HUMAN [Term] id: CCO:B0067296 name: KGP1A_HUMAN-N-acetylserine2 def: "Protein KGP1A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q13976] comment: By similarity xref: UniProtKB:Q13976 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014816 ! KGP1A_HUMAN [Term] id: CCO:B0067297 name: KGP1A_HUMAN-Phosphothreonine59 def: "Protein KGP1A_HUMAN with the residue 59 substituted with Phosphothreonine" [UniProtKB:Q13976] comment: by autocatalysis; By similarity xref: UniProtKB:Q13976 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014816 ! KGP1A_HUMAN [Term] id: CCO:B0067298 name: KHDR1_HUMAN-Phosphoserine15 def: "Protein KHDR1_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q07666] xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0067299 name: KHDR1_HUMAN-Phosphoserine29 def: "Protein KHDR1_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q07666] xref: UniProtKB:Q07666 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:B0067300 name: KI13B_HUMAN-Phosphoserine1379 def: "Protein KI13B_HUMAN with the residue 1379 substituted with Phosphoserine" [UniProtKB:Q9NQT8] xref: UniProtKB:Q9NQT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005849 ! KI13B_HUMAN [Term] id: CCO:B0067301 name: KI13B_HUMAN-Phosphoserine1382 def: "Protein KI13B_HUMAN with the residue 1382 substituted with Phosphoserine" [UniProtKB:Q9NQT8] xref: UniProtKB:Q9NQT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005849 ! KI13B_HUMAN [Term] id: CCO:B0067302 name: KI13B_HUMAN-Phosphoserine1432 def: "Protein KI13B_HUMAN with the residue 1432 substituted with Phosphoserine" [UniProtKB:Q9NQT8] xref: UniProtKB:Q9NQT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005849 ! KI13B_HUMAN [Term] id: CCO:B0067303 name: KI13B_HUMAN-Phosphoserine1438 def: "Protein KI13B_HUMAN with the residue 1438 substituted with Phosphoserine" [UniProtKB:Q9NQT8] xref: UniProtKB:Q9NQT8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005849 ! KI13B_HUMAN [Term] id: CCO:B0067304 name: KI67_HUMAN-Phosphoserine131 def: "Protein KI67_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067305 name: KI67_HUMAN-Phosphoserine264 def: "Protein KI67_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067306 name: KI67_HUMAN-Phosphothreonine347 def: "Protein KI67_HUMAN with the residue 347 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067307 name: KI67_HUMAN-Phosphothreonine401 def: "Protein KI67_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067308 name: KI67_HUMAN-Phosphoserine411 def: "Protein KI67_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067309 name: KI67_HUMAN-Phosphoserine538 def: "Protein KI67_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067310 name: KI67_HUMAN-Phosphothreonine761 def: "Protein KI67_HUMAN with the residue 761 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067311 name: KI67_HUMAN-Phosphoserine859 def: "Protein KI67_HUMAN with the residue 859 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067312 name: KI67_HUMAN-Phosphothreonine1017 def: "Protein KI67_HUMAN with the residue 1017 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067313 name: KI67_HUMAN-Phosphothreonine1111 def: "Protein KI67_HUMAN with the residue 1111 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067314 name: KI67_HUMAN-Phosphothreonine1176 def: "Protein KI67_HUMAN with the residue 1176 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067315 name: KI67_HUMAN-Phosphothreonine1237 def: "Protein KI67_HUMAN with the residue 1237 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067316 name: KI67_HUMAN-Phosphoserine1256 def: "Protein KI67_HUMAN with the residue 1256 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067317 name: KI67_HUMAN-Phosphothreonine1261 def: "Protein KI67_HUMAN with the residue 1261 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067318 name: KI67_HUMAN-Phosphothreonine1315 def: "Protein KI67_HUMAN with the residue 1315 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067319 name: KI67_HUMAN-Phosphothreonine1383 def: "Protein KI67_HUMAN with the residue 1383 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067320 name: KI67_HUMAN-Phosphothreonine1503 def: "Protein KI67_HUMAN with the residue 1503 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067321 name: KI67_HUMAN-Phosphoserine1506 def: "Protein KI67_HUMAN with the residue 1506 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067322 name: KI67_HUMAN-Phosphothreonine1540 def: "Protein KI67_HUMAN with the residue 1540 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067323 name: KI67_HUMAN-Phosphoserine1546 def: "Protein KI67_HUMAN with the residue 1546 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067324 name: KI67_HUMAN-Phosphotyrosine1552 def: "Protein KI67_HUMAN with the residue 1552 substituted with Phosphotyrosine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067325 name: KI67_HUMAN-Phosphothreonine1565 def: "Protein KI67_HUMAN with the residue 1565 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067326 name: KI67_HUMAN-Phosphoserine1571 def: "Protein KI67_HUMAN with the residue 1571 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067327 name: KI67_HUMAN-Phosphoserine1689 def: "Protein KI67_HUMAN with the residue 1689 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067328 name: KI67_HUMAN-Phosphothreonine1719 def: "Protein KI67_HUMAN with the residue 1719 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067329 name: KI67_HUMAN-Phosphoserine1721 def: "Protein KI67_HUMAN with the residue 1721 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067330 name: KI67_HUMAN-Phosphoserine1726 def: "Protein KI67_HUMAN with the residue 1726 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067331 name: KI67_HUMAN-Phosphothreonine1747 def: "Protein KI67_HUMAN with the residue 1747 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067332 name: KI67_HUMAN-Phosphothreonine1784 def: "Protein KI67_HUMAN with the residue 1784 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067333 name: KI67_HUMAN-Phosphothreonine1841 def: "Protein KI67_HUMAN with the residue 1841 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067334 name: KI67_HUMAN-Phosphoserine1864 def: "Protein KI67_HUMAN with the residue 1864 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067335 name: KI67_HUMAN-Phosphothreonine1869 def: "Protein KI67_HUMAN with the residue 1869 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067336 name: KI67_HUMAN-Phosphothreonine2065 def: "Protein KI67_HUMAN with the residue 2065 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067337 name: KI67_HUMAN-Phosphoserine2072 def: "Protein KI67_HUMAN with the residue 2072 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067338 name: KI67_HUMAN-Phosphothreonine2113 def: "Protein KI67_HUMAN with the residue 2113 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067339 name: KI67_HUMAN-Phosphoserine2135 def: "Protein KI67_HUMAN with the residue 2135 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067340 name: KI67_HUMAN-Phosphothreonine2203 def: "Protein KI67_HUMAN with the residue 2203 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067341 name: KI67_HUMAN-Phosphothreonine2211 def: "Protein KI67_HUMAN with the residue 2211 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067342 name: KI67_HUMAN-Phosphoserine2239 def: "Protein KI67_HUMAN with the residue 2239 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067343 name: KI67_HUMAN-Phosphoserine2299 def: "Protein KI67_HUMAN with the residue 2299 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067344 name: KI67_HUMAN-Phosphothreonine2325 def: "Protein KI67_HUMAN with the residue 2325 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067345 name: KI67_HUMAN-Phosphothreonine2328 def: "Protein KI67_HUMAN with the residue 2328 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067346 name: KI67_HUMAN-Phosphothreonine2332 def: "Protein KI67_HUMAN with the residue 2332 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067347 name: KI67_HUMAN-Phosphoserine2344 def: "Protein KI67_HUMAN with the residue 2344 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067348 name: KI67_HUMAN-Phosphothreonine2352 def: "Protein KI67_HUMAN with the residue 2352 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067349 name: KI67_HUMAN-Phosphoserine2355 def: "Protein KI67_HUMAN with the residue 2355 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067350 name: KI67_HUMAN-Phosphothreonine2389 def: "Protein KI67_HUMAN with the residue 2389 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067351 name: KI67_HUMAN-Phosphoserine2395 def: "Protein KI67_HUMAN with the residue 2395 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067352 name: KI67_HUMAN-Phosphoserine2420 def: "Protein KI67_HUMAN with the residue 2420 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067353 name: KI67_HUMAN-Phosphothreonine2426 def: "Protein KI67_HUMAN with the residue 2426 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067354 name: KI67_HUMAN-Phosphothreonine2446 def: "Protein KI67_HUMAN with the residue 2446 substituted with Phosphothreonine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067355 name: KI67_HUMAN-Phosphoserine2466 def: "Protein KI67_HUMAN with the residue 2466 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067356 name: KI67_HUMAN-Phosphoserine2588 def: "Protein KI67_HUMAN with the residue 2588 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067357 name: KI67_HUMAN-Phosphoserine3041 def: "Protein KI67_HUMAN with the residue 3041 substituted with Phosphoserine" [UniProtKB:P46013] xref: UniProtKB:P46013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001622 ! KI67_HUMAN [Term] id: CCO:B0067358 name: KIF15_HUMAN-Phosphoserine568 def: "Protein KIF15_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:Q9NS87] xref: UniProtKB:Q9NS87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002165 ! KIF15_HUMAN [Term] id: CCO:B0067359 name: KIF22_HUMAN-Phosphoserine412 def: "Protein KIF22_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:Q14807] xref: UniProtKB:Q14807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0001792 ! KIF22_HUMAN [Term] id: CCO:B0067360 name: KIF22_HUMAN-Phosphoserine427 def: "Protein KIF22_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q14807] xref: UniProtKB:Q14807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001792 ! KIF22_HUMAN [Term] id: CCO:B0067361 name: KIF23_HUMAN-Phosphothreonine861 def: "Protein KIF23_HUMAN with the residue 861 substituted with Phosphothreonine" [UniProtKB:Q02241] xref: UniProtKB:Q02241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001716 ! KIF23_HUMAN [Term] id: CCO:B0067362 name: KIF2C_HUMAN-Phosphoserine106 def: "Protein KIF2C_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q99661] xref: UniProtKB:Q99661 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000322 ! microtubule motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004138 ! centromeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000431 ! kinesin complex relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0002080 ! KIF2C_HUMAN [Term] id: CCO:B0067363 name: KIF2C_HUMAN-Phosphoserine166 def: "Protein KIF2C_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q99661] xref: UniProtKB:Q99661 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002080 ! KIF2C_HUMAN [Term] id: CCO:B0067364 name: KIT_HUMAN-Phosphotyrosine568 def: "Protein KIT_HUMAN with the residue 568 substituted with Phosphotyrosine" [UniProtKB:P10721] comment: By similarity xref: UniProtKB:P10721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054977 ! KIT_HUMAN [Term] id: CCO:B0067365 name: KIT_HUMAN-Phosphotyrosine570 def: "Protein KIT_HUMAN with the residue 570 substituted with Phosphotyrosine" [UniProtKB:P10721] comment: By similarity xref: UniProtKB:P10721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054977 ! KIT_HUMAN [Term] id: CCO:B0067366 name: KIT_HUMAN-Phosphotyrosine703 def: "Protein KIT_HUMAN with the residue 703 substituted with Phosphotyrosine" [UniProtKB:P10721] comment: By similarity xref: UniProtKB:P10721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001352 ! stem cell factor receptor activity relationship: has_function CCO:F0001353 ! vascular endothelial growth factor receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000702 ! external side of plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054977 ! KIT_HUMAN [Term] id: CCO:B0067367 name: KIT_HUMAN-Phosphotyrosine823 def: "Protein KIT_HUMAN with the residue 823 substituted with Phosphotyrosine" [UniProtKB:P10721] comment: by autocatalysis; By similarity xref: UniProtKB:P10721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054977 ! KIT_HUMAN [Term] id: CCO:B0067368 name: KIT_HUMAN-Phosphotyrosine936 def: "Protein KIT_HUMAN with the residue 936 substituted with Phosphotyrosine" [UniProtKB:P10721] xref: UniProtKB:P10721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054977 ! KIT_HUMAN [Term] id: CCO:B0067369 name: KKCC2_HUMAN-Phosphoserine129 def: "Protein KKCC2_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q96RR4] comment: By similarity xref: UniProtKB:Q96RR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058383 ! KKCC2_HUMAN [Term] id: CCO:B0067370 name: KKCC2_HUMAN-Phosphoserine133 def: "Protein KKCC2_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:Q96RR4] comment: By similarity xref: UniProtKB:Q96RR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001053 ! calmodulin-dependent protein kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058383 ! KKCC2_HUMAN [Term] id: CCO:B0067371 name: KKCC2_HUMAN-Phosphoserine495 def: "Protein KKCC2_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:Q96RR4] comment: By similarity xref: UniProtKB:Q96RR4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058383 ! KKCC2_HUMAN [Term] id: CCO:B0067372 name: KLF10_HUMAN-Phosphoserine249 def: "Protein KLF10_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q13118] xref: UniProtKB:Q13118 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055875 ! KLF10_HUMAN [Term] id: CCO:B0067373 name: KLF14_HUMAN-Phosphothreonine237 def: "Protein KLF14_HUMAN with the residue 237 substituted with Phosphothreonine" [UniProtKB:Q8TD94] xref: UniProtKB:Q8TD94 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057922 ! KLF14_HUMAN [Term] id: CCO:B0067374 name: KLF16_HUMAN-Phosphoserine99 def: "Protein KLF16_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q9BXK1] xref: UniProtKB:Q9BXK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058557 ! KLF16_HUMAN [Term] id: CCO:B0067375 name: KLF16_HUMAN-Phosphoserine102 def: "Protein KLF16_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q9BXK1] xref: UniProtKB:Q9BXK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058557 ! KLF16_HUMAN [Term] id: CCO:B0067376 name: KLF16_HUMAN-Phosphoserine109 def: "Protein KLF16_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q9BXK1] xref: UniProtKB:Q9BXK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058557 ! KLF16_HUMAN [Term] id: CCO:B0067377 name: KLF16_HUMAN-Phosphothreonine152 def: "Protein KLF16_HUMAN with the residue 152 substituted with Phosphothreonine" [UniProtKB:Q9BXK1] xref: UniProtKB:Q9BXK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058557 ! KLF16_HUMAN [Term] id: CCO:B0067378 name: KLF1_HUMAN-Phosphothreonine23 def: "Protein KLF1_HUMAN with the residue 23 substituted with Phosphothreonine" [UniProtKB:Q13351] comment: by CK2; Probable xref: UniProtKB:Q13351 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055900 ! KLF1_HUMAN [Term] id: CCO:B0067379 name: KLF1_HUMAN-N6-acetyllysine274 def: "Protein KLF1_HUMAN with the residue 274 substituted with N6-acetyllysine" [UniProtKB:Q13351] comment: By similarity xref: UniProtKB:Q13351 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055900 ! KLF1_HUMAN [Term] id: CCO:B0067380 name: KLF1_HUMAN-N6-acetyllysine288 def: "Protein KLF1_HUMAN with the residue 288 substituted with N6-acetyllysine" [UniProtKB:Q13351] comment: By similarity xref: UniProtKB:Q13351 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055900 ! KLF1_HUMAN [Term] id: CCO:B0067381 name: KLF3_HUMAN-Phosphoserine92 def: "Protein KLF3_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:P57682] xref: UniProtKB:P57682 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055559 ! KLF3_HUMAN [Term] id: CCO:B0067382 name: KLF3_HUMAN-Phosphoserine101 def: "Protein KLF3_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:P57682] xref: UniProtKB:P57682 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055559 ! KLF3_HUMAN [Term] id: CCO:B0067383 name: KLF3_HUMAN-Phosphoserine250 def: "Protein KLF3_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:P57682] xref: UniProtKB:P57682 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055559 ! KLF3_HUMAN [Term] id: CCO:B0067384 name: KLH12_HUMAN-Phosphothreonine31 def: "Protein KLH12_HUMAN with the residue 31 substituted with Phosphothreonine" [UniProtKB:Q53G59] xref: UniProtKB:Q53G59 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056358 ! KLH12_HUMAN [Term] id: CCO:B0067385 name: KLH12_HUMAN-Phosphothreonine36 def: "Protein KLH12_HUMAN with the residue 36 substituted with Phosphothreonine" [UniProtKB:Q53G59] xref: UniProtKB:Q53G59 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056358 ! KLH12_HUMAN [Term] id: CCO:B0067386 name: KLOT_HUMAN-Phosphotyrosine497 def: "Protein KLOT_HUMAN with the residue 497 substituted with Phosphotyrosine" [UniProtKB:Q9UEF7] comment: By similarity xref: UniProtKB:Q9UEF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059108 ! KLOT_HUMAN [Term] id: CCO:B0067387 name: KNG1_HUMAN-acid19 def: "Protein KNG1_HUMAN with the residue 19 substituted with acid" [UniProtKB:P01042] comment: in mature form; By similarity xref: UniProtKB:P01042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001224 ! cysteine protease inhibitor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0054832 ! KNG1_HUMAN [Term] id: CCO:B0067388 name: KNG1_HUMAN-4-hydroxyproline383 def: "Protein KNG1_HUMAN with the residue 383 substituted with 4-hydroxyproline" [UniProtKB:P01042] comment: partial; xref: UniProtKB:P01042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054832 ! KNG1_HUMAN [Term] id: CCO:B0067389 name: KPCA_HUMAN-Phosphotyrosine195 def: "Protein KPCA_HUMAN with the residue 195 substituted with Phosphotyrosine" [UniProtKB:P17252] xref: UniProtKB:P17252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001529 ! KPCA_HUMAN [Term] id: CCO:B0067390 name: KPCD1_HUMAN-Phosphotyrosine95 def: "Protein KPCD1_HUMAN with the residue 95 substituted with Phosphotyrosine" [UniProtKB:Q15139] xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067391 name: KPCD1_HUMAN-Phosphoserine205 def: "Protein KPCD1_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:Q15139] xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067392 name: KPCD1_HUMAN-Phosphothreonine210 def: "Protein KPCD1_HUMAN with the residue 210 substituted with Phosphothreonine" [UniProtKB:Q15139] xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067393 name: KPCD1_HUMAN-Phosphotyrosine432 def: "Protein KPCD1_HUMAN with the residue 432 substituted with Phosphotyrosine" [UniProtKB:Q15139] xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067394 name: KPCD1_HUMAN-Phosphotyrosine463 def: "Protein KPCD1_HUMAN with the residue 463 substituted with Phosphotyrosine" [UniProtKB:Q15139] xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067395 name: KPCD1_HUMAN-Phosphotyrosine502 def: "Protein KPCD1_HUMAN with the residue 502 substituted with Phosphotyrosine" [UniProtKB:Q15139] xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067396 name: KPCD1_HUMAN-Phosphoserine738 def: "Protein KPCD1_HUMAN with the residue 738 substituted with Phosphoserine" [UniProtKB:Q15139] comment: By similarity xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067397 name: KPCD1_HUMAN-Phosphoserine742 def: "Protein KPCD1_HUMAN with the residue 742 substituted with Phosphoserine" [UniProtKB:Q15139] comment: By similarity xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067398 name: KPCD1_HUMAN-Phosphoserine910 def: "Protein KPCD1_HUMAN with the residue 910 substituted with Phosphoserine" [UniProtKB:Q15139] comment: by autocatalysis; By similarity xref: UniProtKB:Q15139 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:B0067399 name: KPCD2_HUMAN-Phosphoserine197 def: "Protein KPCD2_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q9BZL6] xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067400 name: KPCD2_HUMAN-Phosphoserine198 def: "Protein KPCD2_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:Q9BZL6] xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067401 name: KPCD2_HUMAN-Phosphoserine200 def: "Protein KPCD2_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q9BZL6] xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067402 name: KPCD2_HUMAN-Phosphoserine203 def: "Protein KPCD2_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q9BZL6] xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067403 name: KPCD2_HUMAN-Phosphoserine206 def: "Protein KPCD2_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q9BZL6] xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067404 name: KPCD2_HUMAN-Phosphoserine212 def: "Protein KPCD2_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q9BZL6] comment: By similarity xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067405 name: KPCD2_HUMAN-Phosphoserine214 def: "Protein KPCD2_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q9BZL6] xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067406 name: KPCD2_HUMAN-Phosphoserine710 def: "Protein KPCD2_HUMAN with the residue 710 substituted with Phosphoserine" [UniProtKB:Q9BZL6] xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067407 name: KPCD2_HUMAN-Phosphoserine876 def: "Protein KPCD2_HUMAN with the residue 876 substituted with Phosphoserine" [UniProtKB:Q9BZL6] comment: by autocatalysis; xref: UniProtKB:Q9BZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058604 ! KPCD2_HUMAN [Term] id: CCO:B0067408 name: KPCD3_HUMAN-Phosphoserine41 def: "Protein KPCD3_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:O94806] xref: UniProtKB:O94806 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054699 ! KPCD3_HUMAN [Term] id: CCO:B0067409 name: KPCD3_HUMAN-Phosphoserine44 def: "Protein KPCD3_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:O94806] xref: UniProtKB:O94806 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054699 ! KPCD3_HUMAN [Term] id: CCO:B0067410 name: KPCD3_HUMAN-Phosphoserine213 def: "Protein KPCD3_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:O94806] comment: By similarity xref: UniProtKB:O94806 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054699 ! KPCD3_HUMAN [Term] id: CCO:B0067411 name: KPCD3_HUMAN-Phosphoserine216 def: "Protein KPCD3_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:O94806] comment: By similarity xref: UniProtKB:O94806 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054699 ! KPCD3_HUMAN [Term] id: CCO:B0067412 name: KPCD3_HUMAN-Phosphoserine364 def: "Protein KPCD3_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:O94806] xref: UniProtKB:O94806 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054699 ! KPCD3_HUMAN [Term] id: CCO:B0067413 name: KPCD3_HUMAN-Phosphoserine391 def: "Protein KPCD3_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:O94806] xref: UniProtKB:O94806 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054699 ! KPCD3_HUMAN [Term] id: CCO:B0067414 name: KPCD3_HUMAN-Phosphoserine735 def: "Protein KPCD3_HUMAN with the residue 735 substituted with Phosphoserine" [UniProtKB:O94806] xref: UniProtKB:O94806 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054699 ! KPCD3_HUMAN [Term] id: CCO:B0067415 name: KPCD_HUMAN-Phosphoserine130 def: "Protein KPCD_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067416 name: KPCD_HUMAN-Phosphoserine302 def: "Protein KPCD_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067417 name: KPCD_HUMAN-Phosphoserine304 def: "Protein KPCD_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067418 name: KPCD_HUMAN-Phosphoserine307 def: "Protein KPCD_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067419 name: KPCD_HUMAN-Phosphotyrosine313 def: "Protein KPCD_HUMAN with the residue 313 substituted with Phosphotyrosine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067420 name: KPCD_HUMAN-Phosphotyrosine334 def: "Protein KPCD_HUMAN with the residue 334 substituted with Phosphotyrosine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067421 name: KPCD_HUMAN-Phosphotyrosine374 def: "Protein KPCD_HUMAN with the residue 374 substituted with Phosphotyrosine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067422 name: KPCD_HUMAN-Phosphothreonine507 def: "Protein KPCD_HUMAN with the residue 507 substituted with Phosphothreonine" [UniProtKB:Q05655] comment: by PDPK1; By similarity xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067423 name: KPCD_HUMAN-Phosphoserine645 def: "Protein KPCD_HUMAN with the residue 645 substituted with Phosphoserine" [UniProtKB:Q05655] comment: Potential xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067424 name: KPCD_HUMAN-Phosphoserine664 def: "Protein KPCD_HUMAN with the residue 664 substituted with Phosphoserine" [UniProtKB:Q05655] xref: UniProtKB:Q05655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:B0067425 name: KPCE_HUMAN-Phosphothreonine309 def: "Protein KPCE_HUMAN with the residue 309 substituted with Phosphothreonine" [UniProtKB:Q02156] xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0067426 name: KPCE_HUMAN-Phosphoserine316 def: "Protein KPCE_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q02156] xref: UniProtKB:Q02156 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025054 ! KPCE_HUMAN [Term] id: CCO:B0067427 name: KPCL_HUMAN-Phosphoserine28 def: "Protein KPCL_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:P24723] comment: by autocatalysis; Probable xref: UniProtKB:P24723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025046 ! KPCL_HUMAN [Term] id: CCO:B0067428 name: KPCL_HUMAN-Phosphoserine32 def: "Protein KPCL_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:P24723] comment: by autocatalysis; Probable xref: UniProtKB:P24723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025046 ! KPCL_HUMAN [Term] id: CCO:B0067429 name: KPCL_HUMAN-Phosphothreonine513 def: "Protein KPCL_HUMAN with the residue 513 substituted with Phosphothreonine" [UniProtKB:P24723] comment: Probable xref: UniProtKB:P24723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025046 ! KPCL_HUMAN [Term] id: CCO:B0067430 name: KPCL_HUMAN-Phosphothreonine656 def: "Protein KPCL_HUMAN with the residue 656 substituted with Phosphothreonine" [UniProtKB:P24723] comment: Probable xref: UniProtKB:P24723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025046 ! KPCL_HUMAN [Term] id: CCO:B0067431 name: KPCL_HUMAN-Phosphoserine675 def: "Protein KPCL_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:P24723] comment: Probable xref: UniProtKB:P24723 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001064 ! protein kinase C activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025046 ! KPCL_HUMAN [Term] id: CCO:B0067432 name: KPYM_HUMAN-N-acetylserine2 def: "Protein KPYM_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P14618] xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067433 name: KPYM_HUMAN-Phosphoserine37 def: "Protein KPYM_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:P14618] xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067434 name: KPYM_HUMAN-Phosphothreonine45 def: "Protein KPYM_HUMAN with the residue 45 substituted with Phosphothreonine" [UniProtKB:P14618] xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067435 name: KPYM_HUMAN-Phosphotyrosine83 def: "Protein KPYM_HUMAN with the residue 83 substituted with Phosphotyrosine" [UniProtKB:P14618] xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001108 ! pyruvate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067436 name: KPYM_HUMAN-Phosphotyrosine105 def: "Protein KPYM_HUMAN with the residue 105 substituted with Phosphotyrosine" [UniProtKB:P14618] xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067437 name: KPYM_HUMAN-Phosphotyrosine148 def: "Protein KPYM_HUMAN with the residue 148 substituted with Phosphotyrosine" [UniProtKB:P14618] comment: By similarity xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067438 name: KPYM_HUMAN-Phosphothreonine328 def: "Protein KPYM_HUMAN with the residue 328 substituted with Phosphothreonine" [UniProtKB:P14618] xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067439 name: KPYM_HUMAN-Phosphotyrosine390 def: "Protein KPYM_HUMAN with the residue 390 substituted with Phosphotyrosine" [UniProtKB:P14618] xref: UniProtKB:P14618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:B0067440 name: KRBA2_HUMAN-Phosphoserine115 def: "Protein KRBA2_HUMAN with the residue 115 substituted with Phosphoserine" [UniProtKB:Q6ZNG9] xref: UniProtKB:Q6ZNG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057025 ! KRBA2_HUMAN [Term] id: CCO:B0067441 name: KRBA2_HUMAN-Phosphothreonine117 def: "Protein KRBA2_HUMAN with the residue 117 substituted with Phosphothreonine" [UniProtKB:Q6ZNG9] xref: UniProtKB:Q6ZNG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057025 ! KRBA2_HUMAN [Term] id: CCO:B0067442 name: KRBA2_HUMAN-Phosphotyrosine125 def: "Protein KRBA2_HUMAN with the residue 125 substituted with Phosphotyrosine" [UniProtKB:Q6ZNG9] xref: UniProtKB:Q6ZNG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057025 ! KRBA2_HUMAN [Term] id: CCO:B0067443 name: KRBA2_HUMAN-Phosphoserine483 def: "Protein KRBA2_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:Q6ZNG9] xref: UniProtKB:Q6ZNG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057025 ! KRBA2_HUMAN [Term] id: CCO:B0067444 name: KRR1_HUMAN-N-acetylalanine2 def: "Protein KRR1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q13601] xref: UniProtKB:Q13601 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062817 ! KRR1_HUMAN [Term] id: CCO:B0067445 name: KRR1_HUMAN-Phosphoserine3 def: "Protein KRR1_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:Q13601] xref: UniProtKB:Q13601 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062817 ! KRR1_HUMAN [Term] id: CCO:B0067446 name: KRR1_HUMAN-Phosphoserine336 def: "Protein KRR1_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:Q13601] xref: UniProtKB:Q13601 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062817 ! KRR1_HUMAN [Term] id: CCO:B0067447 name: KRR1_HUMAN-Phosphothreonine337 def: "Protein KRR1_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:Q13601] xref: UniProtKB:Q13601 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000322 ! small nucleolar ribonucleoprotein complex relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0062817 ! KRR1_HUMAN [Term] id: CCO:B0067448 name: KRR1_HUMAN-Phosphothreonine339 def: "Protein KRR1_HUMAN with the residue 339 substituted with Phosphothreonine" [UniProtKB:Q13601] xref: UniProtKB:Q13601 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062817 ! KRR1_HUMAN [Term] id: CCO:B0067449 name: KS6A1_HUMAN-Phosphoserine221 def: "Protein KS6A1_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067450 name: KS6A1_HUMAN-Phosphothreonine225 def: "Protein KS6A1_HUMAN with the residue 225 substituted with Phosphothreonine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067451 name: KS6A1_HUMAN-Phosphothreonine348 def: "Protein KS6A1_HUMAN with the residue 348 substituted with Phosphothreonine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067452 name: KS6A1_HUMAN-Phosphothreonine359 def: "Protein KS6A1_HUMAN with the residue 359 substituted with Phosphothreonine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067453 name: KS6A1_HUMAN-Phosphoserine363 def: "Protein KS6A1_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067454 name: KS6A1_HUMAN-Phosphoserine369 def: "Protein KS6A1_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067455 name: KS6A1_HUMAN-Phosphoserine380 def: "Protein KS6A1_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q15418] comment: by autocatalysis; xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067456 name: KS6A1_HUMAN-Phosphothreonine573 def: "Protein KS6A1_HUMAN with the residue 573 substituted with Phosphothreonine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067457 name: KS6A1_HUMAN-Phosphoserine732 def: "Protein KS6A1_HUMAN with the residue 732 substituted with Phosphoserine" [UniProtKB:Q15418] xref: UniProtKB:Q15418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:B0067458 name: KS6A2_HUMAN-Phosphoserine218 def: "Protein KS6A2_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q15349] xref: UniProtKB:Q15349 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0028634 ! KS6A2_HUMAN [Term] id: CCO:B0067459 name: KS6A2_HUMAN-Phosphothreonine356 def: "Protein KS6A2_HUMAN with the residue 356 substituted with Phosphothreonine" [UniProtKB:Q15349] comment: By similarity xref: UniProtKB:Q15349 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028634 ! KS6A2_HUMAN [Term] id: CCO:B0067460 name: KS6A2_HUMAN-Phosphoserine360 def: "Protein KS6A2_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q15349] comment: By similarity xref: UniProtKB:Q15349 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028634 ! KS6A2_HUMAN [Term] id: CCO:B0067461 name: KS6A2_HUMAN-Phosphoserine377 def: "Protein KS6A2_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q15349] comment: by autocatalysis; By similarity xref: UniProtKB:Q15349 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028634 ! KS6A2_HUMAN [Term] id: CCO:B0067462 name: KS6A2_HUMAN-Phosphothreonine570 def: "Protein KS6A2_HUMAN with the residue 570 substituted with Phosphothreonine" [UniProtKB:Q15349] comment: By similarity xref: UniProtKB:Q15349 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028634 ! KS6A2_HUMAN [Term] id: CCO:B0067463 name: KS6A2_HUMAN-Phosphoserine730 def: "Protein KS6A2_HUMAN with the residue 730 substituted with Phosphoserine" [UniProtKB:Q15349] comment: By similarity xref: UniProtKB:Q15349 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028634 ! KS6A2_HUMAN [Term] id: CCO:B0067464 name: KS6A3_HUMAN-Phosphoserine227 def: "Protein KS6A3_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P51812] xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067465 name: KS6A3_HUMAN-Phosphothreonine231 def: "Protein KS6A3_HUMAN with the residue 231 substituted with Phosphothreonine" [UniProtKB:P51812] xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067466 name: KS6A3_HUMAN-Phosphothreonine365 def: "Protein KS6A3_HUMAN with the residue 365 substituted with Phosphothreonine" [UniProtKB:P51812] xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067467 name: KS6A3_HUMAN-Phosphoserine369 def: "Protein KS6A3_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:P51812] xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067468 name: KS6A3_HUMAN-Phosphoserine375 def: "Protein KS6A3_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:P51812] xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067469 name: KS6A3_HUMAN-Phosphoserine386 def: "Protein KS6A3_HUMAN with the residue 386 substituted with Phosphoserine" [UniProtKB:P51812] comment: By similarity xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067470 name: KS6A3_HUMAN-Phosphothreonine577 def: "Protein KS6A3_HUMAN with the residue 577 substituted with Phosphothreonine" [UniProtKB:P51812] comment: By similarity xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067471 name: KS6A3_HUMAN-Phosphoserine715 def: "Protein KS6A3_HUMAN with the residue 715 substituted with Phosphoserine" [UniProtKB:P51812] xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067472 name: KS6A3_HUMAN-Phosphoserine737 def: "Protein KS6A3_HUMAN with the residue 737 substituted with Phosphoserine" [UniProtKB:P51812] comment: By similarity xref: UniProtKB:P51812 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028618 ! KS6A3_HUMAN [Term] id: CCO:B0067473 name: KS6A5_HUMAN-Phosphoserine212 def: "Protein KS6A5_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:O75582] comment: by autocatalysis; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067474 name: KS6A5_HUMAN-Phosphoserine360 def: "Protein KS6A5_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:O75582] comment: by MAPK3, MAPK1 and MAPK14; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067475 name: KS6A5_HUMAN-Phosphoserine376 def: "Protein KS6A5_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:O75582] comment: by autocatalysis; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067476 name: KS6A5_HUMAN-Phosphoserine381 def: "Protein KS6A5_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:O75582] comment: by autocatalysis; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067477 name: KS6A5_HUMAN-Phosphothreonine581 def: "Protein KS6A5_HUMAN with the residue 581 substituted with Phosphothreonine" [UniProtKB:O75582] comment: by MAPK1, MAPK3 and MAPK14; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067478 name: KS6A5_HUMAN-Phosphoserine750 def: "Protein KS6A5_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:O75582] comment: by autocatalysis; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067479 name: KS6A5_HUMAN-Phosphoserine752 def: "Protein KS6A5_HUMAN with the residue 752 substituted with Phosphoserine" [UniProtKB:O75582] comment: by autocatalysis; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067480 name: KS6A5_HUMAN-Phosphoserine758 def: "Protein KS6A5_HUMAN with the residue 758 substituted with Phosphoserine" [UniProtKB:O75582] comment: by autocatalysis; xref: UniProtKB:O75582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:B0067481 name: KS6A6_HUMAN-Phosphoserine232 def: "Protein KS6A6_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q9UK32] xref: UniProtKB:Q9UK32 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028620 ! KS6A6_HUMAN [Term] id: CCO:B0067482 name: KS6A6_HUMAN-Phosphothreonine368 def: "Protein KS6A6_HUMAN with the residue 368 substituted with Phosphothreonine" [UniProtKB:Q9UK32] comment: By similarity xref: UniProtKB:Q9UK32 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028620 ! KS6A6_HUMAN [Term] id: CCO:B0067483 name: KS6A6_HUMAN-Phosphoserine372 def: "Protein KS6A6_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q9UK32] comment: By similarity xref: UniProtKB:Q9UK32 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028620 ! KS6A6_HUMAN [Term] id: CCO:B0067484 name: KS6A6_HUMAN-Phosphoserine389 def: "Protein KS6A6_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:Q9UK32] comment: By similarity xref: UniProtKB:Q9UK32 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028620 ! KS6A6_HUMAN [Term] id: CCO:B0067485 name: KS6A6_HUMAN-Phosphothreonine581 def: "Protein KS6A6_HUMAN with the residue 581 substituted with Phosphothreonine" [UniProtKB:Q9UK32] comment: By similarity xref: UniProtKB:Q9UK32 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028620 ! KS6A6_HUMAN [Term] id: CCO:B0067486 name: KS6A6_HUMAN-Phosphoserine742 def: "Protein KS6A6_HUMAN with the residue 742 substituted with Phosphoserine" [UniProtKB:Q9UK32] comment: By similarity xref: UniProtKB:Q9UK32 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028620 ! KS6A6_HUMAN [Term] id: CCO:B0067487 name: KS6B1_HUMAN-Phosphoserine441 def: "Protein KS6B1_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:P23443] xref: UniProtKB:P23443 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0028633 ! KS6B1_HUMAN [Term] id: CCO:B0067488 name: KS6B1_HUMAN-Phosphothreonine444 def: "Protein KS6B1_HUMAN with the residue 444 substituted with Phosphothreonine" [UniProtKB:P23443] xref: UniProtKB:P23443 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028633 ! KS6B1_HUMAN [Term] id: CCO:B0067489 name: KS6B1_HUMAN-Phosphoserine447 def: "Protein KS6B1_HUMAN with the residue 447 substituted with Phosphoserine" [UniProtKB:P23443] xref: UniProtKB:P23443 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028633 ! KS6B1_HUMAN [Term] id: CCO:B0067490 name: KS6C1_HUMAN-Phosphoserine423 def: "Protein KS6C1_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:Q96S38] xref: UniProtKB:Q96S38 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058385 ! KS6C1_HUMAN [Term] id: CCO:B0067491 name: KS6C1_HUMAN-Phosphoserine427 def: "Protein KS6C1_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q96S38] xref: UniProtKB:Q96S38 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058385 ! KS6C1_HUMAN [Term] id: CCO:B0067492 name: KS6C1_HUMAN-Phosphoserine583 def: "Protein KS6C1_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:Q96S38] comment: By similarity xref: UniProtKB:Q96S38 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058385 ! KS6C1_HUMAN [Term] id: CCO:B0067493 name: KS6C1_HUMAN-Phosphoserine640 def: "Protein KS6C1_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q96S38] comment: By similarity xref: UniProtKB:Q96S38 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058385 ! KS6C1_HUMAN [Term] id: CCO:B0067494 name: KSR1_HUMAN-Phosphothreonine268 def: "Protein KSR1_HUMAN with the residue 268 substituted with Phosphothreonine" [UniProtKB:Q8IVT5] xref: UniProtKB:Q8IVT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057348 ! KSR1_HUMAN [Term] id: CCO:B0067495 name: KSR1_HUMAN-Phosphothreonine272 def: "Protein KSR1_HUMAN with the residue 272 substituted with Phosphothreonine" [UniProtKB:Q8IVT5] xref: UniProtKB:Q8IVT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057348 ! KSR1_HUMAN [Term] id: CCO:B0067496 name: KSR1_HUMAN-Phosphoserine309 def: "Protein KSR1_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:Q8IVT5] xref: UniProtKB:Q8IVT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057348 ! KSR1_HUMAN [Term] id: CCO:B0067497 name: KSR1_HUMAN-Phosphoserine332 def: "Protein KSR1_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:Q8IVT5] xref: UniProtKB:Q8IVT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057348 ! KSR1_HUMAN [Term] id: CCO:B0067498 name: KSR1_HUMAN-Phosphoserine404 def: "Protein KSR1_HUMAN with the residue 404 substituted with Phosphoserine" [UniProtKB:Q8IVT5] xref: UniProtKB:Q8IVT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057348 ! KSR1_HUMAN [Term] id: CCO:B0067499 name: KSR1_HUMAN-Phosphoserine567 def: "Protein KSR1_HUMAN with the residue 567 substituted with Phosphoserine" [UniProtKB:Q8IVT5] xref: UniProtKB:Q8IVT5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057348 ! KSR1_HUMAN [Term] id: CCO:B0067500 name: KSR2_HUMAN-Phosphoserine474 def: "Protein KSR2_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:Q6VAB6] comment: by MARK3; By similarity xref: UniProtKB:Q6VAB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056960 ! KSR2_HUMAN [Term] id: CCO:B0067501 name: KSYK_HUMAN-Phosphotyrosine296 def: "Protein KSYK_HUMAN with the residue 296 substituted with Phosphotyrosine" [UniProtKB:P43405] xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067502 name: KSYK_HUMAN-Phosphoserine297 def: "Protein KSYK_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:P43405] xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067503 name: KSYK_HUMAN-Phosphoserine316 def: "Protein KSYK_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:P43405] comment: By similarity xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067504 name: KSYK_HUMAN-Phosphoserine319 def: "Protein KSYK_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:P43405] comment: By similarity xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067505 name: KSYK_HUMAN-Phosphotyrosine323 def: "Protein KSYK_HUMAN with the residue 323 substituted with Phosphotyrosine" [UniProtKB:P43405] comment: by LYN; xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000889 ! B cell receptor complex relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067506 name: KSYK_HUMAN-Phosphotyrosine348 def: "Protein KSYK_HUMAN with the residue 348 substituted with Phosphotyrosine" [UniProtKB:P43405] xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067507 name: KSYK_HUMAN-Phosphotyrosine352 def: "Protein KSYK_HUMAN with the residue 352 substituted with Phosphotyrosine" [UniProtKB:P43405] xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067508 name: KSYK_HUMAN-Phosphotyrosine525 def: "Protein KSYK_HUMAN with the residue 525 substituted with Phosphotyrosine" [UniProtKB:P43405] comment: by autocatalysis; By similarity xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067509 name: KSYK_HUMAN-Phosphotyrosine526 def: "Protein KSYK_HUMAN with the residue 526 substituted with Phosphotyrosine" [UniProtKB:P43405] xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067510 name: KSYK_HUMAN-Phosphotyrosine546 def: "Protein KSYK_HUMAN with the residue 546 substituted with Phosphotyrosine" [UniProtKB:P43405] comment: By similarity xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067511 name: KSYK_HUMAN-Phosphotyrosine629 def: "Protein KSYK_HUMAN with the residue 629 substituted with Phosphotyrosine" [UniProtKB:P43405] comment: By similarity xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067512 name: KSYK_HUMAN-Phosphotyrosine630 def: "Protein KSYK_HUMAN with the residue 630 substituted with Phosphotyrosine" [UniProtKB:P43405] comment: By similarity xref: UniProtKB:P43405 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:B0067513 name: KTN1_HUMAN-Phosphoserine75 def: "Protein KTN1_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q86UP2] xref: UniProtKB:Q86UP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063140 ! KTN1_HUMAN [Term] id: CCO:B0067514 name: KTN1_HUMAN-Phosphoserine77 def: "Protein KTN1_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q86UP2] xref: UniProtKB:Q86UP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063140 ! KTN1_HUMAN [Term] id: CCO:B0067515 name: KTN1_HUMAN-Phosphothreonine153 def: "Protein KTN1_HUMAN with the residue 153 substituted with Phosphothreonine" [UniProtKB:Q86UP2] xref: UniProtKB:Q86UP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063140 ! KTN1_HUMAN [Term] id: CCO:B0067516 name: KTN1_HUMAN-Phosphoserine156 def: "Protein KTN1_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q86UP2] xref: UniProtKB:Q86UP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063140 ! KTN1_HUMAN [Term] id: CCO:B0067517 name: L2GL2_HUMAN-Phosphoserine1015 def: "Protein L2GL2_HUMAN with the residue 1015 substituted with Phosphoserine" [UniProtKB:Q6P1M3] xref: UniProtKB:Q6P1M3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001913 ! L2GL2_HUMAN [Term] id: CCO:B0067518 name: LAIR1_HUMAN-Phosphotyrosine251 def: "Protein LAIR1_HUMAN with the residue 251 substituted with Phosphotyrosine" [UniProtKB:Q6GTX8] xref: UniProtKB:Q6GTX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062981 ! LAIR1_HUMAN [Term] id: CCO:B0067519 name: LAIR1_HUMAN-Phosphotyrosine281 def: "Protein LAIR1_HUMAN with the residue 281 substituted with Phosphotyrosine" [UniProtKB:Q6GTX8] xref: UniProtKB:Q6GTX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062981 ! LAIR1_HUMAN [Term] id: CCO:B0067520 name: LAP2A_HUMAN-Phosphoserine66 def: "Protein LAP2A_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001652 ! lamin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067521 name: LAP2A_HUMAN-Phosphoserine67 def: "Protein LAP2A_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067522 name: LAP2A_HUMAN-Phosphothreonine74 def: "Protein LAP2A_HUMAN with the residue 74 substituted with Phosphothreonine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067523 name: LAP2A_HUMAN-Phosphoserine79 def: "Protein LAP2A_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067524 name: LAP2A_HUMAN-Phosphoserine156 def: "Protein LAP2A_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067525 name: LAP2A_HUMAN-Phosphothreonine160 def: "Protein LAP2A_HUMAN with the residue 160 substituted with Phosphothreonine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067526 name: LAP2A_HUMAN-Phosphothreonine164 def: "Protein LAP2A_HUMAN with the residue 164 substituted with Phosphothreonine" [UniProtKB:P42166] comment: By similarity xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067527 name: LAP2A_HUMAN-Phosphoserine168 def: "Protein LAP2A_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067528 name: LAP2A_HUMAN-Phosphoserine177 def: "Protein LAP2A_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:P42166] comment: By similarity xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067529 name: LAP2A_HUMAN-Phosphoserine180 def: "Protein LAP2A_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:P42166] comment: By similarity xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067530 name: LAP2A_HUMAN-Phosphoserine184 def: "Protein LAP2A_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067531 name: LAP2A_HUMAN-Phosphoserine272 def: "Protein LAP2A_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067532 name: LAP2A_HUMAN-Phosphoserine310 def: "Protein LAP2A_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067533 name: LAP2A_HUMAN-Phosphoserine351 def: "Protein LAP2A_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067534 name: LAP2A_HUMAN-Phosphoserine370 def: "Protein LAP2A_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067535 name: LAP2A_HUMAN-Phosphoserine424 def: "Protein LAP2A_HUMAN with the residue 424 substituted with Phosphoserine" [UniProtKB:P42166] xref: UniProtKB:P42166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:B0067536 name: LAP2_HUMAN-Phosphoserine569 def: "Protein LAP2_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0067537 name: LAP2_HUMAN-Phosphoserine934 def: "Protein LAP2_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0067538 name: LAP2_HUMAN-Phosphoserine1060 def: "Protein LAP2_HUMAN with the residue 1060 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0067539 name: LAP2_HUMAN-Phosphoserine1286 def: "Protein LAP2_HUMAN with the residue 1286 substituted with Phosphoserine" [UniProtKB:Q96RT1] xref: UniProtKB:Q96RT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002059 ! LAP2_HUMAN [Term] id: CCO:B0067540 name: LAP4_HUMAN-Phosphoserine35 def: "Protein LAP4_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067541 name: LAP4_HUMAN-Phosphoserine487 def: "Protein LAP4_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067542 name: LAP4_HUMAN-Phosphoserine504 def: "Protein LAP4_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067543 name: LAP4_HUMAN-Phosphothreonine689 def: "Protein LAP4_HUMAN with the residue 689 substituted with Phosphothreonine" [UniProtKB:Q14160] comment: By similarity xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067544 name: LAP4_HUMAN-Phosphothreonine749 def: "Protein LAP4_HUMAN with the residue 749 substituted with Phosphothreonine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067545 name: LAP4_HUMAN-Phosphothreonine826 def: "Protein LAP4_HUMAN with the residue 826 substituted with Phosphothreonine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067546 name: LAP4_HUMAN-Phosphotyrosine834 def: "Protein LAP4_HUMAN with the residue 834 substituted with Phosphotyrosine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067547 name: LAP4_HUMAN-Phosphoserine835 def: "Protein LAP4_HUMAN with the residue 835 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067548 name: LAP4_HUMAN-Phosphoserine853 def: "Protein LAP4_HUMAN with the residue 853 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067549 name: LAP4_HUMAN-Phosphoserine939 def: "Protein LAP4_HUMAN with the residue 939 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067550 name: LAP4_HUMAN-Phosphothreonine941 def: "Protein LAP4_HUMAN with the residue 941 substituted with Phosphothreonine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067551 name: LAP4_HUMAN-Phosphoserine1140 def: "Protein LAP4_HUMAN with the residue 1140 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067552 name: LAP4_HUMAN-Phosphoserine1220 def: "Protein LAP4_HUMAN with the residue 1220 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067553 name: LAP4_HUMAN-Phosphoserine1223 def: "Protein LAP4_HUMAN with the residue 1223 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067554 name: LAP4_HUMAN-Phosphoserine1225 def: "Protein LAP4_HUMAN with the residue 1225 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067555 name: LAP4_HUMAN-Phosphoserine1226 def: "Protein LAP4_HUMAN with the residue 1226 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067556 name: LAP4_HUMAN-Phosphoserine1232 def: "Protein LAP4_HUMAN with the residue 1232 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067557 name: LAP4_HUMAN-Phosphoserine1306 def: "Protein LAP4_HUMAN with the residue 1306 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067558 name: LAP4_HUMAN-Phosphoserine1309 def: "Protein LAP4_HUMAN with the residue 1309 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067559 name: LAP4_HUMAN-Phosphothreonine1342 def: "Protein LAP4_HUMAN with the residue 1342 substituted with Phosphothreonine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067560 name: LAP4_HUMAN-Phosphoserine1348 def: "Protein LAP4_HUMAN with the residue 1348 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067561 name: LAP4_HUMAN-Phosphotyrosine1360 def: "Protein LAP4_HUMAN with the residue 1360 substituted with Phosphotyrosine" [UniProtKB:Q14160] comment: By similarity xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067562 name: LAP4_HUMAN-Phosphoserine1378 def: "Protein LAP4_HUMAN with the residue 1378 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067563 name: LAP4_HUMAN-Phosphoserine1437 def: "Protein LAP4_HUMAN with the residue 1437 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067564 name: LAP4_HUMAN-Phosphoserine1439 def: "Protein LAP4_HUMAN with the residue 1439 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067565 name: LAP4_HUMAN-Phosphoserine1448 def: "Protein LAP4_HUMAN with the residue 1448 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067566 name: LAP4_HUMAN-Phosphoserine1475 def: "Protein LAP4_HUMAN with the residue 1475 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067567 name: LAP4_HUMAN-Phosphoserine1486 def: "Protein LAP4_HUMAN with the residue 1486 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067568 name: LAP4_HUMAN-Phosphoserine1508 def: "Protein LAP4_HUMAN with the residue 1508 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067569 name: LAP4_HUMAN-Phosphoserine1547 def: "Protein LAP4_HUMAN with the residue 1547 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067570 name: LAP4_HUMAN-Phosphoserine1561 def: "Protein LAP4_HUMAN with the residue 1561 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067571 name: LAP4_HUMAN-Phosphoserine1566 def: "Protein LAP4_HUMAN with the residue 1566 substituted with Phosphoserine" [UniProtKB:Q14160] xref: UniProtKB:Q14160 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:B0067572 name: LASP1_HUMAN-N-acetylmethionine1 def: "Protein LASP1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q14847] xref: UniProtKB:Q14847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062943 ! LASP1_HUMAN [Term] id: CCO:B0067573 name: LASP1_HUMAN-Phosphothreonine68 def: "Protein LASP1_HUMAN with the residue 68 substituted with Phosphothreonine" [UniProtKB:Q14847] xref: UniProtKB:Q14847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062943 ! LASP1_HUMAN [Term] id: CCO:B0067574 name: LASP1_HUMAN-Phosphothreonine104 def: "Protein LASP1_HUMAN with the residue 104 substituted with Phosphothreonine" [UniProtKB:Q14847] xref: UniProtKB:Q14847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062943 ! LASP1_HUMAN [Term] id: CCO:B0067575 name: LASP1_HUMAN-Phosphoserine146 def: "Protein LASP1_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q14847] xref: UniProtKB:Q14847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002557 ! ion transmembrane transporter activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0001056 ! cortical actin cytoskeleton relationship: transformation_of CCO:B0062943 ! LASP1_HUMAN [Term] id: CCO:B0067576 name: LASP1_HUMAN-Phosphoserine151 def: "Protein LASP1_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q14847] xref: UniProtKB:Q14847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062943 ! LASP1_HUMAN [Term] id: CCO:B0067577 name: LASP1_HUMAN-Phosphotyrosine171 def: "Protein LASP1_HUMAN with the residue 171 substituted with Phosphotyrosine" [UniProtKB:Q14847] xref: UniProtKB:Q14847 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062943 ! LASP1_HUMAN [Term] id: CCO:B0067578 name: LATS2_HUMAN-Phosphothreonine279 def: "Protein LATS2_HUMAN with the residue 279 substituted with Phosphothreonine" [UniProtKB:Q9NRM7] xref: UniProtKB:Q9NRM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002159 ! LATS2_HUMAN [Term] id: CCO:B0067579 name: LATS2_HUMAN-Phosphoserine380 def: "Protein LATS2_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q9NRM7] xref: UniProtKB:Q9NRM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000144 ! spindle pole relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: transformation_of CCO:B0002159 ! LATS2_HUMAN [Term] id: CCO:B0067580 name: LAT_HUMAN-Phosphothreonine39 def: "Protein LAT_HUMAN with the residue 39 substituted with Phosphothreonine" [UniProtKB:O43561] xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067581 name: LAT_HUMAN-Phosphoserine84 def: "Protein LAT_HUMAN with the residue 84 substituted with Phosphoserine" [UniProtKB:O43561] xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000186 ! immunological synapse relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067582 name: LAT_HUMAN-Phosphoserine101 def: "Protein LAT_HUMAN with the residue 101 substituted with Phosphoserine" [UniProtKB:O43561] xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067583 name: LAT_HUMAN-Phosphoserine109 def: "Protein LAT_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:O43561] xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067584 name: LAT_HUMAN-Phosphotyrosine110 def: "Protein LAT_HUMAN with the residue 110 substituted with Phosphotyrosine" [UniProtKB:O43561] comment: Probable xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067585 name: LAT_HUMAN-Phosphotyrosine156 def: "Protein LAT_HUMAN with the residue 156 substituted with Phosphotyrosine" [UniProtKB:O43561] comment: Probable xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067586 name: LAT_HUMAN-Phosphotyrosine161 def: "Protein LAT_HUMAN with the residue 161 substituted with Phosphotyrosine" [UniProtKB:O43561] comment: Probable xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067587 name: LAT_HUMAN-Phosphotyrosine200 def: "Protein LAT_HUMAN with the residue 200 substituted with Phosphotyrosine" [UniProtKB:O43561] xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067588 name: LAT_HUMAN-Phosphotyrosine220 def: "Protein LAT_HUMAN with the residue 220 substituted with Phosphotyrosine" [UniProtKB:O43561] comment: Probable xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067589 name: LAT_HUMAN-Phosphoserine224 def: "Protein LAT_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:O43561] xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067590 name: LAT_HUMAN-Phosphotyrosine255 def: "Protein LAT_HUMAN with the residue 255 substituted with Phosphotyrosine" [UniProtKB:O43561] comment: Probable xref: UniProtKB:O43561 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054492 ! LAT_HUMAN [Term] id: CCO:B0067591 name: LAX1_HUMAN-Phosphotyrosine193 def: "Protein LAX1_HUMAN with the residue 193 substituted with Phosphotyrosine" [UniProtKB:Q8IWV1] comment: Probable xref: UniProtKB:Q8IWV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057364 ! LAX1_HUMAN [Term] id: CCO:B0067592 name: LAX1_HUMAN-Phosphotyrosine268 def: "Protein LAX1_HUMAN with the residue 268 substituted with Phosphotyrosine" [UniProtKB:Q8IWV1] comment: Probable xref: UniProtKB:Q8IWV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057364 ! LAX1_HUMAN [Term] id: CCO:B0067593 name: LAX1_HUMAN-Phosphotyrosine294 def: "Protein LAX1_HUMAN with the residue 294 substituted with Phosphotyrosine" [UniProtKB:Q8IWV1] comment: Probable xref: UniProtKB:Q8IWV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057364 ! LAX1_HUMAN [Term] id: CCO:B0067594 name: LAX1_HUMAN-Phosphotyrosine373 def: "Protein LAX1_HUMAN with the residue 373 substituted with Phosphotyrosine" [UniProtKB:Q8IWV1] comment: Probable xref: UniProtKB:Q8IWV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0057364 ! LAX1_HUMAN [Term] id: CCO:B0067595 name: LBH_HUMAN-Phosphoserine63 def: "Protein LBH_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:Q53QV2] xref: UniProtKB:Q53QV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056363 ! LBH_HUMAN [Term] id: CCO:B0067596 name: LBH_HUMAN-Phosphothreonine69 def: "Protein LBH_HUMAN with the residue 69 substituted with Phosphothreonine" [UniProtKB:Q53QV2] xref: UniProtKB:Q53QV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056363 ! LBH_HUMAN [Term] id: CCO:B0067597 name: LCOR_HUMAN-Phosphoserine351 def: "Protein LCOR_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q96JN0] xref: UniProtKB:Q96JN0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058246 ! LCOR_HUMAN [Term] id: CCO:B0067598 name: LCOR_HUMAN-Phosphoserine359 def: "Protein LCOR_HUMAN with the residue 359 substituted with Phosphoserine" [UniProtKB:Q96JN0] xref: UniProtKB:Q96JN0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058246 ! LCOR_HUMAN [Term] id: CCO:B0067599 name: LCOR_HUMAN-Phosphoserine363 def: "Protein LCOR_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q96JN0] xref: UniProtKB:Q96JN0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058246 ! LCOR_HUMAN [Term] id: CCO:B0067600 name: LCOR_HUMAN-Phosphoserine367 def: "Protein LCOR_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q96JN0] xref: UniProtKB:Q96JN0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058246 ! LCOR_HUMAN [Term] id: CCO:B0067601 name: LCP2_HUMAN-Phosphotyrosine23 def: "Protein LCP2_HUMAN with the residue 23 substituted with Phosphotyrosine" [UniProtKB:Q13094] comment: By similarity xref: UniProtKB:Q13094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055872 ! LCP2_HUMAN [Term] id: CCO:B0067602 name: LCP2_HUMAN-Phosphotyrosine173 def: "Protein LCP2_HUMAN with the residue 173 substituted with Phosphotyrosine" [UniProtKB:Q13094] xref: UniProtKB:Q13094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055872 ! LCP2_HUMAN [Term] id: CCO:B0067603 name: LCP2_HUMAN-Phosphoserine207 def: "Protein LCP2_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:Q13094] xref: UniProtKB:Q13094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055872 ! LCP2_HUMAN [Term] id: CCO:B0067604 name: LDHA_HUMAN-N-acetylalanine2 def: "Protein LDHA_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P00338] xref: UniProtKB:P00338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063179 ! LDHA_HUMAN [Term] id: CCO:B0067605 name: LDHA_HUMAN-Phosphotyrosine239 def: "Protein LDHA_HUMAN with the residue 239 substituted with Phosphotyrosine" [UniProtKB:P00338] xref: UniProtKB:P00338 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000859 ! L-lactate dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0063179 ! LDHA_HUMAN [Term] id: CCO:B0067606 name: LDHB_HUMAN-N-acetylalanine2 def: "Protein LDHB_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P07195] xref: UniProtKB:P07195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063130 ! LDHB_HUMAN [Term] id: CCO:B0067607 name: LDHB_HUMAN-Phosphotyrosine240 def: "Protein LDHB_HUMAN with the residue 240 substituted with Phosphotyrosine" [UniProtKB:P07195] xref: UniProtKB:P07195 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000859 ! L-lactate dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063130 ! LDHB_HUMAN [Term] id: CCO:B0067608 name: LDLR_HUMAN-Phosphotyrosine845 def: "Protein LDLR_HUMAN with the residue 845 substituted with Phosphotyrosine" [UniProtKB:P01130] xref: UniProtKB:P01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001362 ! low-density lipoprotein receptor activity relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_function CCO:F0004352 ! very-low-density lipoprotein receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001033 ! clathrin-coated endocytic vesicle membrane relationship: transformation_of CCO:B0063373 ! LDLR_HUMAN [Term] id: CCO:B0067609 name: LEG1_HUMAN-N-acetylalanine2 def: "Protein LEG1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P09382] xref: UniProtKB:P09382 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054942 ! LEG1_HUMAN [Term] id: CCO:B0067610 name: LEG3_HUMAN-N-acetylalanine2 def: "Protein LEG3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P17931] comment: By similarity xref: UniProtKB:P17931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063286 ! LEG3_HUMAN [Term] id: CCO:B0067611 name: LEG3_HUMAN-Phosphoserine6 def: "Protein LEG3_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:P17931] xref: UniProtKB:P17931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063286 ! LEG3_HUMAN [Term] id: CCO:B0067612 name: LEG3_HUMAN-Phosphoserine12 def: "Protein LEG3_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:P17931] xref: UniProtKB:P17931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063286 ! LEG3_HUMAN [Term] id: CCO:B0067613 name: LEO1_HUMAN-Phosphoserine10 def: "Protein LEO1_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067614 name: LEO1_HUMAN-Phosphoserine14 def: "Protein LEO1_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067615 name: LEO1_HUMAN-Phosphoserine151 def: "Protein LEO1_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067616 name: LEO1_HUMAN-Phosphoserine154 def: "Protein LEO1_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067617 name: LEO1_HUMAN-Phosphoserine162 def: "Protein LEO1_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067618 name: LEO1_HUMAN-Phosphoserine171 def: "Protein LEO1_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067619 name: LEO1_HUMAN-Phosphoserine179 def: "Protein LEO1_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067620 name: LEO1_HUMAN-Phosphothreonine188 def: "Protein LEO1_HUMAN with the residue 188 substituted with Phosphothreonine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067621 name: LEO1_HUMAN-Phosphoserine197 def: "Protein LEO1_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067622 name: LEO1_HUMAN-Phosphoserine205 def: "Protein LEO1_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067623 name: LEO1_HUMAN-Phosphoserine212 def: "Protein LEO1_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067624 name: LEO1_HUMAN-Phosphoserine220 def: "Protein LEO1_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067625 name: LEO1_HUMAN-Phosphoserine229 def: "Protein LEO1_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067626 name: LEO1_HUMAN-Phosphoserine238 def: "Protein LEO1_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067627 name: LEO1_HUMAN-Phosphoserine271 def: "Protein LEO1_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067628 name: LEO1_HUMAN-Phosphoserine277 def: "Protein LEO1_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067629 name: LEO1_HUMAN-Phosphoserine279 def: "Protein LEO1_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067630 name: LEO1_HUMAN-Phosphoserine294 def: "Protein LEO1_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067631 name: LEO1_HUMAN-Phosphoserine296 def: "Protein LEO1_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067632 name: LEO1_HUMAN-Phosphoserine300 def: "Protein LEO1_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067633 name: LEO1_HUMAN-Phosphothreonine302 def: "Protein LEO1_HUMAN with the residue 302 substituted with Phosphothreonine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067634 name: LEO1_HUMAN-Phosphoserine551 def: "Protein LEO1_HUMAN with the residue 551 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067635 name: LEO1_HUMAN-Phosphoserine607 def: "Protein LEO1_HUMAN with the residue 607 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067636 name: LEO1_HUMAN-Phosphoserine608 def: "Protein LEO1_HUMAN with the residue 608 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067637 name: LEO1_HUMAN-Phosphoserine610 def: "Protein LEO1_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067638 name: LEO1_HUMAN-Phosphoserine614 def: "Protein LEO1_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067639 name: LEO1_HUMAN-Phosphothreonine629 def: "Protein LEO1_HUMAN with the residue 629 substituted with Phosphothreonine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067640 name: LEO1_HUMAN-Phosphoserine630 def: "Protein LEO1_HUMAN with the residue 630 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067641 name: LEO1_HUMAN-Phosphoserine658 def: "Protein LEO1_HUMAN with the residue 658 substituted with Phosphoserine" [UniProtKB:Q8WVC0] xref: UniProtKB:Q8WVC0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:B0067642 name: LEUK_HUMAN-Phosphoserine355 def: "Protein LEUK_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:P16150] xref: UniProtKB:P16150 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055047 ! LEUK_HUMAN [Term] id: CCO:B0067643 name: LGR6_HUMAN-Phosphoserine457 def: "Protein LGR6_HUMAN with the residue 457 substituted with Phosphoserine" [UniProtKB:Q9HBX8] xref: UniProtKB:Q9HBX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003181 ! protein-hormone receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058794 ! LGR6_HUMAN [Term] id: CCO:B0067644 name: LHX5_HUMAN-Phosphotyrosine119 def: "Protein LHX5_HUMAN with the residue 119 substituted with Phosphotyrosine" [UniProtKB:Q9H2C1] xref: UniProtKB:Q9H2C1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058680 ! LHX5_HUMAN [Term] id: CCO:B0067645 name: LIFR_HUMAN-Phosphoserine927 def: "Protein LIFR_HUMAN with the residue 927 substituted with Phosphoserine" [UniProtKB:P42702] xref: UniProtKB:P42702 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055355 ! LIFR_HUMAN [Term] id: CCO:B0067646 name: LIMA1_HUMAN-Phosphoserine15 def: "Protein LIMA1_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067647 name: LIMA1_HUMAN-Phosphoserine132 def: "Protein LIMA1_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067648 name: LIMA1_HUMAN-Phosphoserine225 def: "Protein LIMA1_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067649 name: LIMA1_HUMAN-Phosphotyrosine229 def: "Protein LIMA1_HUMAN with the residue 229 substituted with Phosphotyrosine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067650 name: LIMA1_HUMAN-Phosphoserine230 def: "Protein LIMA1_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067651 name: LIMA1_HUMAN-Phosphoserine362 def: "Protein LIMA1_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067652 name: LIMA1_HUMAN-Phosphoserine365 def: "Protein LIMA1_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067653 name: LIMA1_HUMAN-Phosphoserine369 def: "Protein LIMA1_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:Q9UHB6] comment: By similarity xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067654 name: LIMA1_HUMAN-Phosphoserine374 def: "Protein LIMA1_HUMAN with the residue 374 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067655 name: LIMA1_HUMAN-Phosphothreonine487 def: "Protein LIMA1_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067656 name: LIMA1_HUMAN-Phosphoserine490 def: "Protein LIMA1_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067657 name: LIMA1_HUMAN-Phosphoserine541 def: "Protein LIMA1_HUMAN with the residue 541 substituted with Phosphoserine" [UniProtKB:Q9UHB6] comment: By similarity xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0000324 ! actin monomer binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067658 name: LIMA1_HUMAN-Phosphoserine604 def: "Protein LIMA1_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067659 name: LIMA1_HUMAN-Phosphoserine609 def: "Protein LIMA1_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067660 name: LIMA1_HUMAN-Phosphoserine617 def: "Protein LIMA1_HUMAN with the residue 617 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067661 name: LIMA1_HUMAN-Phosphoserine619 def: "Protein LIMA1_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067662 name: LIMA1_HUMAN-Phosphoserine622 def: "Protein LIMA1_HUMAN with the residue 622 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067663 name: LIMA1_HUMAN-Phosphoserine686 def: "Protein LIMA1_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067664 name: LIMA1_HUMAN-Phosphoserine692 def: "Protein LIMA1_HUMAN with the residue 692 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067665 name: LIMA1_HUMAN-Phosphoserine698 def: "Protein LIMA1_HUMAN with the residue 698 substituted with Phosphoserine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067666 name: LIMA1_HUMAN-Phosphotyrosine752 def: "Protein LIMA1_HUMAN with the residue 752 substituted with Phosphotyrosine" [UniProtKB:Q9UHB6] xref: UniProtKB:Q9UHB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:B0067667 name: LIMD1_HUMAN-Phosphoserine296 def: "Protein LIMD1_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q9UGP4] xref: UniProtKB:Q9UGP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031064 ! LIMD1_HUMAN [Term] id: CCO:B0067668 name: LIMD1_HUMAN-Phosphoserine304 def: "Protein LIMD1_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q9UGP4] xref: UniProtKB:Q9UGP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031064 ! LIMD1_HUMAN [Term] id: CCO:B0067669 name: LIMD1_HUMAN-Phosphoserine421 def: "Protein LIMD1_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q9UGP4] xref: UniProtKB:Q9UGP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031064 ! LIMD1_HUMAN [Term] id: CCO:B0067670 name: LIMD1_HUMAN-Phosphoserine424 def: "Protein LIMD1_HUMAN with the residue 424 substituted with Phosphoserine" [UniProtKB:Q9UGP4] xref: UniProtKB:Q9UGP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031064 ! LIMD1_HUMAN [Term] id: CCO:B0067671 name: LIMK1_HUMAN-Phosphoserine302 def: "Protein LIMK1_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:P53667] xref: UniProtKB:P53667 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:B0067672 name: LIMK1_HUMAN-Phosphoserine307 def: "Protein LIMK1_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:P53667] xref: UniProtKB:P53667 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:B0067673 name: LIMS1_HUMAN-N-acetylalanine2 def: "Protein LIMS1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P48059] xref: UniProtKB:P48059 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062873 ! LIMS1_HUMAN [Term] id: CCO:B0067674 name: LIN9_HUMAN-Phosphoserine65 def: "Protein LIN9_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q5TKA1] xref: UniProtKB:Q5TKA1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001894 ! LIN9_HUMAN [Term] id: CCO:B0067675 name: LIN9_HUMAN-Phosphothreonine297 def: "Protein LIN9_HUMAN with the residue 297 substituted with Phosphothreonine" [UniProtKB:Q5TKA1] xref: UniProtKB:Q5TKA1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001894 ! LIN9_HUMAN [Term] id: CCO:B0067676 name: LIN9_HUMAN-Phosphothreonine304 def: "Protein LIN9_HUMAN with the residue 304 substituted with Phosphothreonine" [UniProtKB:Q5TKA1] xref: UniProtKB:Q5TKA1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001894 ! LIN9_HUMAN [Term] id: CCO:B0067677 name: LIPA1_HUMAN-Phosphothreonine230 def: "Protein LIPA1_HUMAN with the residue 230 substituted with Phosphothreonine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0067678 name: LIPA1_HUMAN-Phosphoserine244 def: "Protein LIPA1_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0067679 name: LIPA1_HUMAN-Phosphoserine741 def: "Protein LIPA1_HUMAN with the residue 741 substituted with Phosphoserine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0067680 name: LIPA1_HUMAN-Phosphoserine745 def: "Protein LIPA1_HUMAN with the residue 745 substituted with Phosphoserine" [UniProtKB:Q13136] xref: UniProtKB:Q13136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:B0067681 name: LIRB3_HUMAN-Phosphothreonine480 def: "Protein LIRB3_HUMAN with the residue 480 substituted with Phosphothreonine" [UniProtKB:O75022] xref: UniProtKB:O75022 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054593 ! LIRB3_HUMAN [Term] id: CCO:B0067682 name: LIRB4_HUMAN-Phosphotyrosine360 def: "Protein LIRB4_HUMAN with the residue 360 substituted with Phosphotyrosine" [UniProtKB:Q8NHJ6] xref: UniProtKB:Q8NHJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057875 ! LIRB4_HUMAN [Term] id: CCO:B0067683 name: LMBL2_HUMAN-Phosphoserine12 def: "Protein LMBL2_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q969R5] xref: UniProtKB:Q969R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:B0067684 name: LMBL2_HUMAN-Phosphoserine13 def: "Protein LMBL2_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:Q969R5] xref: UniProtKB:Q969R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:B0067685 name: LMBL2_HUMAN-Phosphothreonine66 def: "Protein LMBL2_HUMAN with the residue 66 substituted with Phosphothreonine" [UniProtKB:Q969R5] xref: UniProtKB:Q969R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:B0067686 name: LMBL2_HUMAN-Phosphothreonine76 def: "Protein LMBL2_HUMAN with the residue 76 substituted with Phosphothreonine" [UniProtKB:Q969R5] xref: UniProtKB:Q969R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:B0067687 name: LMBL2_HUMAN-Phosphoserine683 def: "Protein LMBL2_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:Q969R5] xref: UniProtKB:Q969R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:B0067688 name: LMBL2_HUMAN-Phosphoserine688 def: "Protein LMBL2_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:Q969R5] xref: UniProtKB:Q969R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:B0067689 name: LMBL2_HUMAN-Phosphoserine689 def: "Protein LMBL2_HUMAN with the residue 689 substituted with Phosphoserine" [UniProtKB:Q969R5] xref: UniProtKB:Q969R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:B0067690 name: LMBL3_HUMAN-Phosphoserine608 def: "Protein LMBL3_HUMAN with the residue 608 substituted with Phosphoserine" [UniProtKB:Q96JM7] xref: UniProtKB:Q96JM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058245 ! LMBL3_HUMAN [Term] id: CCO:B0067691 name: LMNA_HUMAN-Blocked amino end (Met)1 def: "Protein LMNA_HUMAN with the residue 1 substituted with Blocked amino end (Met)" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067692 name: LMNA_HUMAN-Phosphothreonine10 def: "Protein LMNA_HUMAN with the residue 10 substituted with Phosphothreonine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067693 name: LMNA_HUMAN-Phosphoserine12 def: "Protein LMNA_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:P02545] comment: By similarity xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067694 name: LMNA_HUMAN-Phosphothreonine19 def: "Protein LMNA_HUMAN with the residue 19 substituted with Phosphothreonine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067695 name: LMNA_HUMAN-Phosphoserine22 def: "Protein LMNA_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067696 name: LMNA_HUMAN-Phosphoserine277 def: "Protein LMNA_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067697 name: LMNA_HUMAN-Phosphoserine390 def: "Protein LMNA_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067698 name: LMNA_HUMAN-Phosphoserine392 def: "Protein LMNA_HUMAN with the residue 392 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067699 name: LMNA_HUMAN-Phosphoserine395 def: "Protein LMNA_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067700 name: LMNA_HUMAN-Phosphoserine403 def: "Protein LMNA_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067701 name: LMNA_HUMAN-Phosphoserine404 def: "Protein LMNA_HUMAN with the residue 404 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067702 name: LMNA_HUMAN-Phosphoserine406 def: "Protein LMNA_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067703 name: LMNA_HUMAN-Phosphoserine407 def: "Protein LMNA_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067704 name: LMNA_HUMAN-Phosphothreonine409 def: "Protein LMNA_HUMAN with the residue 409 substituted with Phosphothreonine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067705 name: LMNA_HUMAN-Phosphoserine414 def: "Protein LMNA_HUMAN with the residue 414 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067706 name: LMNA_HUMAN-Phosphothreonine416 def: "Protein LMNA_HUMAN with the residue 416 substituted with Phosphothreonine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067707 name: LMNA_HUMAN-N6-acetyllysine417 def: "Protein LMNA_HUMAN with the residue 417 substituted with N6-acetyllysine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067708 name: LMNA_HUMAN-Phosphoserine423 def: "Protein LMNA_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067709 name: LMNA_HUMAN-Phosphothreonine424 def: "Protein LMNA_HUMAN with the residue 424 substituted with Phosphothreonine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067710 name: LMNA_HUMAN-Phosphothreonine496 def: "Protein LMNA_HUMAN with the residue 496 substituted with Phosphothreonine" [UniProtKB:P02545] comment: By similarity xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067711 name: LMNA_HUMAN-Phosphothreonine505 def: "Protein LMNA_HUMAN with the residue 505 substituted with Phosphothreonine" [UniProtKB:P02545] comment: By similarity xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067712 name: LMNA_HUMAN-Phosphoserine507 def: "Protein LMNA_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:P02545] comment: By similarity xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067713 name: LMNA_HUMAN-Phosphothreonine510 def: "Protein LMNA_HUMAN with the residue 510 substituted with Phosphothreonine" [UniProtKB:P02545] comment: By similarity xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067714 name: LMNA_HUMAN-Phosphoserine628 def: "Protein LMNA_HUMAN with the residue 628 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067715 name: LMNA_HUMAN-Phosphoserine632 def: "Protein LMNA_HUMAN with the residue 632 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067716 name: LMNA_HUMAN-Phosphoserine636 def: "Protein LMNA_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067717 name: LMNA_HUMAN-Phosphoserine652 def: "Protein LMNA_HUMAN with the residue 652 substituted with Phosphoserine" [UniProtKB:P02545] xref: UniProtKB:P02545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:B0067718 name: LMNB1_HUMAN-Phosphoserine13 def: "Protein LMNB1_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067719 name: LMNB1_HUMAN-Phosphothreonine19 def: "Protein LMNB1_HUMAN with the residue 19 substituted with Phosphothreonine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067720 name: LMNB1_HUMAN-Phosphothreonine20 def: "Protein LMNB1_HUMAN with the residue 20 substituted with Phosphothreonine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067721 name: LMNB1_HUMAN-Phosphoserine23 def: "Protein LMNB1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067722 name: LMNB1_HUMAN-Phosphoserine28 def: "Protein LMNB1_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067723 name: LMNB1_HUMAN-Phosphoserine200 def: "Protein LMNB1_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067724 name: LMNB1_HUMAN-Phosphoserine391 def: "Protein LMNB1_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067725 name: LMNB1_HUMAN-Phosphoserine393 def: "Protein LMNB1_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067726 name: LMNB1_HUMAN-Phosphoserine404 def: "Protein LMNB1_HUMAN with the residue 404 substituted with Phosphoserine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067727 name: LMNB1_HUMAN-Phosphothreonine575 def: "Protein LMNB1_HUMAN with the residue 575 substituted with Phosphothreonine" [UniProtKB:P20700] xref: UniProtKB:P20700 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000254 ! nuclear inner membrane relationship: located_in CCO:C0000255 ! lamin filament relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063225 ! LMNB1_HUMAN [Term] id: CCO:B0067728 name: LMO7_HUMAN-Phosphoserine246 def: "Protein LMO7_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067729 name: LMO7_HUMAN-Phosphoserine276 def: "Protein LMO7_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067730 name: LMO7_HUMAN-Phosphoserine322 def: "Protein LMO7_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067731 name: LMO7_HUMAN-Phosphotyrosine323 def: "Protein LMO7_HUMAN with the residue 323 substituted with Phosphotyrosine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067732 name: LMO7_HUMAN-Phosphoserine342 def: "Protein LMO7_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067733 name: LMO7_HUMAN-Phosphoserine345 def: "Protein LMO7_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067734 name: LMO7_HUMAN-Phosphoserine706 def: "Protein LMO7_HUMAN with the residue 706 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067735 name: LMO7_HUMAN-Phosphoserine709 def: "Protein LMO7_HUMAN with the residue 709 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067736 name: LMO7_HUMAN-Phosphoserine805 def: "Protein LMO7_HUMAN with the residue 805 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067737 name: LMO7_HUMAN-Phosphoserine867 def: "Protein LMO7_HUMAN with the residue 867 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067738 name: LMO7_HUMAN-Phosphoserine873 def: "Protein LMO7_HUMAN with the residue 873 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067739 name: LMO7_HUMAN-Phosphoserine895 def: "Protein LMO7_HUMAN with the residue 895 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067740 name: LMO7_HUMAN-Phosphothreonine913 def: "Protein LMO7_HUMAN with the residue 913 substituted with Phosphothreonine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067741 name: LMO7_HUMAN-Phosphoserine919 def: "Protein LMO7_HUMAN with the residue 919 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067742 name: LMO7_HUMAN-Phosphoserine926 def: "Protein LMO7_HUMAN with the residue 926 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067743 name: LMO7_HUMAN-Phosphothreonine932 def: "Protein LMO7_HUMAN with the residue 932 substituted with Phosphothreonine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067744 name: LMO7_HUMAN-Phosphothreonine949 def: "Protein LMO7_HUMAN with the residue 949 substituted with Phosphothreonine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067745 name: LMO7_HUMAN-Phosphoserine955 def: "Protein LMO7_HUMAN with the residue 955 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067746 name: LMO7_HUMAN-Phosphoserine960 def: "Protein LMO7_HUMAN with the residue 960 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067747 name: LMO7_HUMAN-Phosphoserine988 def: "Protein LMO7_HUMAN with the residue 988 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067748 name: LMO7_HUMAN-Phosphoserine991 def: "Protein LMO7_HUMAN with the residue 991 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067749 name: LMO7_HUMAN-Phosphoserine994 def: "Protein LMO7_HUMAN with the residue 994 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067750 name: LMO7_HUMAN-Phosphoserine995 def: "Protein LMO7_HUMAN with the residue 995 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067751 name: LMO7_HUMAN-Phosphoserine1026 def: "Protein LMO7_HUMAN with the residue 1026 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067752 name: LMO7_HUMAN-Phosphoserine1044 def: "Protein LMO7_HUMAN with the residue 1044 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067753 name: LMO7_HUMAN-Phosphothreonine1048 def: "Protein LMO7_HUMAN with the residue 1048 substituted with Phosphothreonine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067754 name: LMO7_HUMAN-Phosphoserine1423 def: "Protein LMO7_HUMAN with the residue 1423 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067755 name: LMO7_HUMAN-Phosphoserine1493 def: "Protein LMO7_HUMAN with the residue 1493 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067756 name: LMO7_HUMAN-Phosphoserine1510 def: "Protein LMO7_HUMAN with the residue 1510 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067757 name: LMO7_HUMAN-Phosphoserine1516 def: "Protein LMO7_HUMAN with the residue 1516 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067758 name: LMO7_HUMAN-Phosphoserine1563 def: "Protein LMO7_HUMAN with the residue 1563 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067759 name: LMO7_HUMAN-Phosphoserine1586 def: "Protein LMO7_HUMAN with the residue 1586 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067760 name: LMO7_HUMAN-Phosphoserine1593 def: "Protein LMO7_HUMAN with the residue 1593 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067761 name: LMO7_HUMAN-Phosphoserine1595 def: "Protein LMO7_HUMAN with the residue 1595 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067762 name: LMO7_HUMAN-Phosphoserine1597 def: "Protein LMO7_HUMAN with the residue 1597 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067763 name: LMO7_HUMAN-Phosphoserine1601 def: "Protein LMO7_HUMAN with the residue 1601 substituted with Phosphoserine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067764 name: LMO7_HUMAN-Phosphotyrosine1672 def: "Protein LMO7_HUMAN with the residue 1672 substituted with Phosphotyrosine" [UniProtKB:Q8WWI1] xref: UniProtKB:Q8WWI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:B0067765 name: LPHN1_HUMAN-Phosphoserine1377 def: "Protein LPHN1_HUMAN with the residue 1377 substituted with Phosphoserine" [UniProtKB:O94910] comment: By similarity xref: UniProtKB:O94910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054710 ! LPHN1_HUMAN [Term] id: CCO:B0067766 name: LPHN1_HUMAN-Phosphotyrosine1440 def: "Protein LPHN1_HUMAN with the residue 1440 substituted with Phosphotyrosine" [UniProtKB:O94910] xref: UniProtKB:O94910 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054710 ! LPHN1_HUMAN [Term] id: CCO:B0067767 name: LPHN2_HUMAN-Phosphoserine1381 def: "Protein LPHN2_HUMAN with the residue 1381 substituted with Phosphoserine" [UniProtKB:O95490] comment: By similarity xref: UniProtKB:O95490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054767 ! LPHN2_HUMAN [Term] id: CCO:B0067768 name: LPHN2_HUMAN-Phosphoserine1387 def: "Protein LPHN2_HUMAN with the residue 1387 substituted with Phosphoserine" [UniProtKB:O95490] comment: By similarity xref: UniProtKB:O95490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054767 ! LPHN2_HUMAN [Term] id: CCO:B0067769 name: LPHN3_HUMAN-Phosphothreonine610 def: "Protein LPHN3_HUMAN with the residue 610 substituted with Phosphothreonine" [UniProtKB:Q9HAR2] xref: UniProtKB:Q9HAR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058766 ! LPHN3_HUMAN [Term] id: CCO:B0067770 name: LPHN3_HUMAN-Phosphothreonine1445 def: "Protein LPHN3_HUMAN with the residue 1445 substituted with Phosphothreonine" [UniProtKB:Q9HAR2] comment: By similarity xref: UniProtKB:Q9HAR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058766 ! LPHN3_HUMAN [Term] id: CCO:B0067771 name: LRC41_HUMAN-Phosphoserine357 def: "Protein LRC41_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q15345] xref: UniProtKB:Q15345 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043602 ! LRC41_HUMAN [Term] id: CCO:B0067772 name: LRC59_HUMAN-Phosphoserine23 def: "Protein LRC59_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q96AG4] xref: UniProtKB:Q96AG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005845 ! LRC59_HUMAN [Term] id: CCO:B0067773 name: LRC59_HUMAN-Phosphoserine25 def: "Protein LRC59_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q96AG4] xref: UniProtKB:Q96AG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005845 ! LRC59_HUMAN [Term] id: CCO:B0067774 name: LRCH4_HUMAN-Phosphoserine182 def: "Protein LRCH4_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:O75427] xref: UniProtKB:O75427 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054634 ! LRCH4_HUMAN [Term] id: CCO:B0067775 name: LRCH4_HUMAN-Phosphoserine183 def: "Protein LRCH4_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:O75427] xref: UniProtKB:O75427 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0054634 ! LRCH4_HUMAN [Term] id: CCO:B0067776 name: LRCH4_HUMAN-Phosphoserine521 def: "Protein LRCH4_HUMAN with the residue 521 substituted with Phosphoserine" [UniProtKB:O75427] xref: UniProtKB:O75427 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054634 ! LRCH4_HUMAN [Term] id: CCO:B0067777 name: LRP2_HUMAN-Phosphoserine4463 def: "Protein LRP2_HUMAN with the residue 4463 substituted with Phosphoserine" [UniProtKB:P98164] comment: By similarity xref: UniProtKB:P98164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000460 ! brush border relationship: located_in CCO:C0000462 ! coated pit relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: transformation_of CCO:B0055671 ! LRP2_HUMAN [Term] id: CCO:B0067778 name: LRP2_HUMAN-Phosphoserine4471 def: "Protein LRP2_HUMAN with the residue 4471 substituted with Phosphoserine" [UniProtKB:P98164] comment: By similarity xref: UniProtKB:P98164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055671 ! LRP2_HUMAN [Term] id: CCO:B0067779 name: LRRF1_HUMAN-Phosphoserine120 def: "Protein LRRF1_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0067780 name: LRRF1_HUMAN-Phosphoserine124 def: "Protein LRRF1_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0067781 name: LRRF1_HUMAN-Phosphoserine581 def: "Protein LRRF1_HUMAN with the residue 581 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0067782 name: LRRF1_HUMAN-Phosphoserine618 def: "Protein LRRF1_HUMAN with the residue 618 substituted with Phosphoserine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0067783 name: LRRF1_HUMAN-Phosphothreonine676 def: "Protein LRRF1_HUMAN with the residue 676 substituted with Phosphothreonine" [UniProtKB:Q32MZ4] xref: UniProtKB:Q32MZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032520 ! LRRF1_HUMAN [Term] id: CCO:B0067784 name: LRSM1_HUMAN-Phosphoserine234 def: "Protein LRSM1_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q6UWE0] xref: UniProtKB:Q6UWE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006335 ! LRSM1_HUMAN [Term] id: CCO:B0067785 name: LRSM1_HUMAN-Phosphoserine604 def: "Protein LRSM1_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:Q6UWE0] xref: UniProtKB:Q6UWE0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0006335 ! LRSM1_HUMAN [Term] id: CCO:B0067786 name: LSM2_HUMAN-Phosphotyrosine35 def: "Protein LSM2_HUMAN with the residue 35 substituted with Phosphotyrosine" [UniProtKB:Q9Y333] xref: UniProtKB:Q9Y333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062972 ! LSM2_HUMAN [Term] id: CCO:B0067787 name: LSM2_HUMAN-Phosphothreonine79 def: "Protein LSM2_HUMAN with the residue 79 substituted with Phosphothreonine" [UniProtKB:Q9Y333] xref: UniProtKB:Q9Y333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003545 ! U6 snRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0062972 ! LSM2_HUMAN [Term] id: CCO:B0067788 name: LSM4_HUMAN-N-acetylmethionine1 def: "Protein LSM4_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q9Y4Z0] xref: UniProtKB:Q9Y4Z0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063157 ! LSM4_HUMAN [Term] id: CCO:B0067789 name: LSP1_HUMAN-Phosphoserine85 def: "Protein LSP1_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:P33241] comment: By similarity xref: UniProtKB:P33241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055265 ! LSP1_HUMAN [Term] id: CCO:B0067790 name: LSP1_HUMAN-Phosphothreonine175 def: "Protein LSP1_HUMAN with the residue 175 substituted with Phosphothreonine" [UniProtKB:P33241] comment: By similarity xref: UniProtKB:P33241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055265 ! LSP1_HUMAN [Term] id: CCO:B0067791 name: LSP1_HUMAN-Phosphoserine177 def: "Protein LSP1_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:P33241] comment: By similarity xref: UniProtKB:P33241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055265 ! LSP1_HUMAN [Term] id: CCO:B0067792 name: LSP1_HUMAN-Phosphoserine252 def: "Protein LSP1_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:P33241] comment: by MAPKAPK2; xref: UniProtKB:P33241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055265 ! LSP1_HUMAN [Term] id: CCO:B0067793 name: LST1_HUMAN-Phosphotyrosine88 def: "Protein LST1_HUMAN with the residue 88 substituted with Phosphotyrosine" [UniProtKB:O00453] xref: UniProtKB:O00453 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054322 ! LST1_HUMAN [Term] id: CCO:B0067794 name: LTK_HUMAN-Phosphotyrosine672 def: "Protein LTK_HUMAN with the residue 672 substituted with Phosphotyrosine" [UniProtKB:P29376] xref: UniProtKB:P29376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055214 ! LTK_HUMAN [Term] id: CCO:B0067795 name: LTK_HUMAN-Phosphotyrosine676 def: "Protein LTK_HUMAN with the residue 676 substituted with Phosphotyrosine" [UniProtKB:P29376] comment: by autocatalysis; By similarity xref: UniProtKB:P29376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055214 ! LTK_HUMAN [Term] id: CCO:B0067796 name: LTK_HUMAN-Phosphotyrosine677 def: "Protein LTK_HUMAN with the residue 677 substituted with Phosphotyrosine" [UniProtKB:P29376] xref: UniProtKB:P29376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055214 ! LTK_HUMAN [Term] id: CCO:B0067797 name: LYAR_HUMAN-Phosphoserine244 def: "Protein LYAR_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:Q9NX58] xref: UniProtKB:Q9NX58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063383 ! LYAR_HUMAN [Term] id: CCO:B0067798 name: LYAR_HUMAN-Phosphoserine258 def: "Protein LYAR_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q9NX58] xref: UniProtKB:Q9NX58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0063383 ! LYAR_HUMAN [Term] id: CCO:B0067799 name: LYAR_HUMAN-Phosphoserine276 def: "Protein LYAR_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q9NX58] xref: UniProtKB:Q9NX58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063383 ! LYAR_HUMAN [Term] id: CCO:B0067800 name: LYN_HUMAN-Phosphotyrosine306 def: "Protein LYN_HUMAN with the residue 306 substituted with Phosphotyrosine" [UniProtKB:P07948] xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0067801 name: LYN_HUMAN-Phosphotyrosine473 def: "Protein LYN_HUMAN with the residue 473 substituted with Phosphotyrosine" [UniProtKB:P07948] xref: UniProtKB:P07948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:B0067802 name: LYOX_HUMAN-2',4',5'-topaquinone355 def: "Protein LYOX_HUMAN with the residue 355 substituted with 2',4',5'-topaquinone" [UniProtKB:P28300] comment: By similarity xref: UniProtKB:P28300 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055199 ! LYOX_HUMAN [Term] id: CCO:B0067803 name: LYST_HUMAN-Phosphoserine2213 def: "Protein LYST_HUMAN with the residue 2213 substituted with Phosphoserine" [UniProtKB:Q99698] comment: By similarity xref: UniProtKB:Q99698 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: transformation_of CCO:B0058442 ! LYST_HUMAN [Term] id: CCO:B0067804 name: LYST_HUMAN-Phosphoserine2217 def: "Protein LYST_HUMAN with the residue 2217 substituted with Phosphoserine" [UniProtKB:Q99698] comment: By similarity xref: UniProtKB:Q99698 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058442 ! LYST_HUMAN [Term] id: CCO:B0067805 name: M3K11_HUMAN-Phosphoserine789 def: "Protein M3K11_HUMAN with the residue 789 substituted with Phosphoserine" [UniProtKB:Q16584] xref: UniProtKB:Q16584 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001820 ! M3K11_HUMAN [Term] id: CCO:B0067806 name: M3K1_HUMAN-Phosphoserine297 def: "Protein M3K1_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0067807 name: M3K1_HUMAN-Phosphoserine300 def: "Protein M3K1_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0067808 name: M3K1_HUMAN-Phosphoserine507 def: "Protein M3K1_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0067809 name: M3K1_HUMAN-Phosphoserine511 def: "Protein M3K1_HUMAN with the residue 511 substituted with Phosphoserine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0067810 name: M3K1_HUMAN-Phosphoserine1020 def: "Protein M3K1_HUMAN with the residue 1020 substituted with Phosphoserine" [UniProtKB:Q13233] xref: UniProtKB:Q13233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:B0067811 name: M3K2_HUMAN-Phosphoserine153 def: "Protein M3K2_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:Q9Y2U5] xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067812 name: M3K2_HUMAN-Phosphoserine159 def: "Protein M3K2_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:Q9Y2U5] xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067813 name: M3K2_HUMAN-Phosphoserine163 def: "Protein M3K2_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:Q9Y2U5] xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067814 name: M3K2_HUMAN-Phosphoserine164 def: "Protein M3K2_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q9Y2U5] xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067815 name: M3K2_HUMAN-Phosphoserine297 def: "Protein M3K2_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:Q9Y2U5] xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067816 name: M3K2_HUMAN-Phosphothreonine304 def: "Protein M3K2_HUMAN with the residue 304 substituted with Phosphothreonine" [UniProtKB:Q9Y2U5] comment: By similarity xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067817 name: M3K2_HUMAN-Phosphoserine331 def: "Protein M3K2_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q9Y2U5] comment: By similarity xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001075 ! MAP kinase kinase kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067818 name: M3K2_HUMAN-Phosphothreonine524 def: "Protein M3K2_HUMAN with the residue 524 substituted with Phosphothreonine" [UniProtKB:Q9Y2U5] comment: By similarity xref: UniProtKB:Q9Y2U5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:B0067819 name: M3K6_HUMAN-Phosphothreonine806 def: "Protein M3K6_HUMAN with the residue 806 substituted with Phosphothreonine" [UniProtKB:O95382] comment: By similarity xref: UniProtKB:O95382 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054754 ! M3K6_HUMAN [Term] id: CCO:B0067820 name: M3K8_HUMAN-Phosphoserine141 def: "Protein M3K8_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:P41279] xref: UniProtKB:P41279 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005520 ! M3K8_HUMAN [Term] id: CCO:B0067821 name: M3KL4_HUMAN-Phosphoserine614 def: "Protein M3KL4_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:Q5TCX8] xref: UniProtKB:Q5TCX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018759 ! M3KL4_HUMAN [Term] id: CCO:B0067822 name: M4K1_HUMAN-Phosphoserine366 def: "Protein M4K1_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067823 name: M4K1_HUMAN-Phosphoserine368 def: "Protein M4K1_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067824 name: M4K1_HUMAN-Phosphoserine374 def: "Protein M4K1_HUMAN with the residue 374 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067825 name: M4K1_HUMAN-Phosphoserine376 def: "Protein M4K1_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067826 name: M4K1_HUMAN-Phosphotyrosine381 def: "Protein M4K1_HUMAN with the residue 381 substituted with Phosphotyrosine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067827 name: M4K1_HUMAN-Phosphoserine407 def: "Protein M4K1_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067828 name: M4K1_HUMAN-Phosphoserine413 def: "Protein M4K1_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001845 ! MAP kinase kinase kinase kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067829 name: M4K1_HUMAN-Phosphoserine421 def: "Protein M4K1_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067830 name: M4K1_HUMAN-Phosphoserine586 def: "Protein M4K1_HUMAN with the residue 586 substituted with Phosphoserine" [UniProtKB:Q92918] xref: UniProtKB:Q92918 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:B0067831 name: M4K2_HUMAN-Phosphoserine328 def: "Protein M4K2_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q12851] xref: UniProtKB:Q12851 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005706 ! M4K2_HUMAN [Term] id: CCO:B0067832 name: M4K2_HUMAN-Phosphoserine394 def: "Protein M4K2_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q12851] xref: UniProtKB:Q12851 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005706 ! M4K2_HUMAN [Term] id: CCO:B0067833 name: M4K5_HUMAN-Phosphotyrosine31 def: "Protein M4K5_HUMAN with the residue 31 substituted with Phosphotyrosine" [UniProtKB:Q9Y4K4] xref: UniProtKB:Q9Y4K4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:B0067834 name: M4K5_HUMAN-Phosphoserine335 def: "Protein M4K5_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q9Y4K4] xref: UniProtKB:Q9Y4K4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:B0067835 name: MACF4_HUMAN-Phosphoserine2362 def: "Protein MACF4_HUMAN with the residue 2362 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067836 name: MACF4_HUMAN-Phosphoserine2930 def: "Protein MACF4_HUMAN with the residue 2930 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067837 name: MACF4_HUMAN-Phosphoserine2931 def: "Protein MACF4_HUMAN with the residue 2931 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067838 name: MACF4_HUMAN-Phosphoserine2956 def: "Protein MACF4_HUMAN with the residue 2956 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067839 name: MACF4_HUMAN-Phosphoserine5797 def: "Protein MACF4_HUMAN with the residue 5797 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067840 name: MACF4_HUMAN-Phosphoserine5801 def: "Protein MACF4_HUMAN with the residue 5801 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067841 name: MACF4_HUMAN-Phosphothreonine5804 def: "Protein MACF4_HUMAN with the residue 5804 substituted with Phosphothreonine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067842 name: MACF4_HUMAN-Phosphoserine5842 def: "Protein MACF4_HUMAN with the residue 5842 substituted with Phosphoserine" [UniProtKB:Q96PK2] xref: UniProtKB:Q96PK2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002053 ! MACF4_HUMAN [Term] id: CCO:B0067843 name: MADD_HUMAN-Phosphoserine818 def: "Protein MADD_HUMAN with the residue 818 substituted with Phosphoserine" [UniProtKB:Q8WXG6] xref: UniProtKB:Q8WXG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002010 ! MADD_HUMAN [Term] id: CCO:B0067844 name: MADD_HUMAN-Phosphoserine820 def: "Protein MADD_HUMAN with the residue 820 substituted with Phosphoserine" [UniProtKB:Q8WXG6] xref: UniProtKB:Q8WXG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002010 ! MADD_HUMAN [Term] id: CCO:B0067845 name: MADD_HUMAN-Phosphoserine921 def: "Protein MADD_HUMAN with the residue 921 substituted with Phosphoserine" [UniProtKB:Q8WXG6] xref: UniProtKB:Q8WXG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001425 ! death receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003575 ! Rab guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0004382 ! protein kinase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0002010 ! MADD_HUMAN [Term] id: CCO:B0067846 name: MADD_HUMAN-Phosphoserine1270 def: "Protein MADD_HUMAN with the residue 1270 substituted with Phosphoserine" [UniProtKB:Q8WXG6] xref: UniProtKB:Q8WXG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002010 ! MADD_HUMAN [Term] id: CCO:B0067847 name: MAF1_HUMAN-Phosphoserine60 def: "Protein MAF1_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q9H063] xref: UniProtKB:Q9H063 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005301 ! MAF1_HUMAN [Term] id: CCO:B0067848 name: MAF1_HUMAN-Phosphoserine68 def: "Protein MAF1_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:Q9H063] xref: UniProtKB:Q9H063 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005301 ! MAF1_HUMAN [Term] id: CCO:B0067849 name: MAGD1_HUMAN-Phosphotyrosine92 def: "Protein MAGD1_HUMAN with the residue 92 substituted with Phosphotyrosine" [UniProtKB:Q9Y5V3] xref: UniProtKB:Q9Y5V3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0006204 ! MAGD1_HUMAN [Term] id: CCO:B0067850 name: MAGG1_HUMAN-Phosphoserine57 def: "Protein MAGG1_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:Q96MG7] xref: UniProtKB:Q96MG7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0022490 ! MAGG1_HUMAN [Term] id: CCO:B0067851 name: MAGG1_HUMAN-Phosphoserine60 def: "Protein MAGG1_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q96MG7] xref: UniProtKB:Q96MG7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022490 ! MAGG1_HUMAN [Term] id: CCO:B0067852 name: MAGG1_HUMAN-Phosphoserine64 def: "Protein MAGG1_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q96MG7] xref: UniProtKB:Q96MG7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022490 ! MAGG1_HUMAN [Term] id: CCO:B0067853 name: MAGI1_HUMAN-Phosphotyrosine866 def: "Protein MAGI1_HUMAN with the residue 866 substituted with Phosphotyrosine" [UniProtKB:Q96QZ7] comment: By similarity xref: UniProtKB:Q96QZ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058358 ! MAGI1_HUMAN [Term] id: CCO:B0067854 name: MAGI2_HUMAN-Phosphotyrosine362 def: "Protein MAGI2_HUMAN with the residue 362 substituted with Phosphotyrosine" [UniProtKB:Q86UL8] comment: By similarity xref: UniProtKB:Q86UL8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063032 ! MAGI2_HUMAN [Term] id: CCO:B0067855 name: MAGI2_HUMAN-Phosphotyrosine366 def: "Protein MAGI2_HUMAN with the residue 366 substituted with Phosphotyrosine" [UniProtKB:Q86UL8] comment: By similarity xref: UniProtKB:Q86UL8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063032 ! MAGI2_HUMAN [Term] id: CCO:B0067856 name: MAGI2_HUMAN-Phosphotyrosine827 def: "Protein MAGI2_HUMAN with the residue 827 substituted with Phosphotyrosine" [UniProtKB:Q86UL8] comment: By similarity xref: UniProtKB:Q86UL8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004211 ! phosphatase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0063032 ! MAGI2_HUMAN [Term] id: CCO:B0067857 name: MAGI2_HUMAN-Phosphoserine1014 def: "Protein MAGI2_HUMAN with the residue 1014 substituted with Phosphoserine" [UniProtKB:Q86UL8] comment: By similarity xref: UniProtKB:Q86UL8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063032 ! MAGI2_HUMAN [Term] id: CCO:B0067858 name: MALT1_HUMAN-Phosphoserine135 def: "Protein MALT1_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q9UDY8] xref: UniProtKB:Q9UDY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059106 ! MALT1_HUMAN [Term] id: CCO:B0067859 name: MAP1B_HUMAN-Phosphoserine336 def: "Protein MAP1B_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067860 name: MAP1B_HUMAN-Phosphothreonine527 def: "Protein MAP1B_HUMAN with the residue 527 substituted with Phosphothreonine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067861 name: MAP1B_HUMAN-Phosphoserine541 def: "Protein MAP1B_HUMAN with the residue 541 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067862 name: MAP1B_HUMAN-Phosphoserine544 def: "Protein MAP1B_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067863 name: MAP1B_HUMAN-Phosphoserine561 def: "Protein MAP1B_HUMAN with the residue 561 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067864 name: MAP1B_HUMAN-Phosphothreonine569 def: "Protein MAP1B_HUMAN with the residue 569 substituted with Phosphothreonine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067865 name: MAP1B_HUMAN-Phosphoserine614 def: "Protein MAP1B_HUMAN with the residue 614 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067866 name: MAP1B_HUMAN-Phosphoserine828 def: "Protein MAP1B_HUMAN with the residue 828 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067867 name: MAP1B_HUMAN-Phosphoserine831 def: "Protein MAP1B_HUMAN with the residue 831 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067868 name: MAP1B_HUMAN-Phosphoserine832 def: "Protein MAP1B_HUMAN with the residue 832 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067869 name: MAP1B_HUMAN-Phosphoserine937 def: "Protein MAP1B_HUMAN with the residue 937 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067870 name: MAP1B_HUMAN-Phosphoserine992 def: "Protein MAP1B_HUMAN with the residue 992 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067871 name: MAP1B_HUMAN-Phosphoserine995 def: "Protein MAP1B_HUMAN with the residue 995 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067872 name: MAP1B_HUMAN-Phosphoserine1016 def: "Protein MAP1B_HUMAN with the residue 1016 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067873 name: MAP1B_HUMAN-Phosphotyrosine1062 def: "Protein MAP1B_HUMAN with the residue 1062 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067874 name: MAP1B_HUMAN-Phosphothreonine1067 def: "Protein MAP1B_HUMAN with the residue 1067 substituted with Phosphothreonine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067875 name: MAP1B_HUMAN-Phosphoserine1154 def: "Protein MAP1B_HUMAN with the residue 1154 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067876 name: MAP1B_HUMAN-Phosphoserine1208 def: "Protein MAP1B_HUMAN with the residue 1208 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067877 name: MAP1B_HUMAN-Phosphoserine1252 def: "Protein MAP1B_HUMAN with the residue 1252 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067878 name: MAP1B_HUMAN-Phosphoserine1256 def: "Protein MAP1B_HUMAN with the residue 1256 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067879 name: MAP1B_HUMAN-Phosphoserine1260 def: "Protein MAP1B_HUMAN with the residue 1260 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067880 name: MAP1B_HUMAN-Phosphoserine1265 def: "Protein MAP1B_HUMAN with the residue 1265 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067881 name: MAP1B_HUMAN-Phosphoserine1276 def: "Protein MAP1B_HUMAN with the residue 1276 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067882 name: MAP1B_HUMAN-Phosphoserine1280 def: "Protein MAP1B_HUMAN with the residue 1280 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067883 name: MAP1B_HUMAN-Phosphothreonine1282 def: "Protein MAP1B_HUMAN with the residue 1282 substituted with Phosphothreonine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067884 name: MAP1B_HUMAN-Phosphoserine1312 def: "Protein MAP1B_HUMAN with the residue 1312 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067885 name: MAP1B_HUMAN-Phosphoserine1322 def: "Protein MAP1B_HUMAN with the residue 1322 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067886 name: MAP1B_HUMAN-Phosphoserine1324 def: "Protein MAP1B_HUMAN with the residue 1324 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067887 name: MAP1B_HUMAN-Phosphotyrosine1336 def: "Protein MAP1B_HUMAN with the residue 1336 substituted with Phosphotyrosine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067888 name: MAP1B_HUMAN-Phosphotyrosine1337 def: "Protein MAP1B_HUMAN with the residue 1337 substituted with Phosphotyrosine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067889 name: MAP1B_HUMAN-Phosphoserine1339 def: "Protein MAP1B_HUMAN with the residue 1339 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067890 name: MAP1B_HUMAN-Phosphoserine1376 def: "Protein MAP1B_HUMAN with the residue 1376 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067891 name: MAP1B_HUMAN-Phosphoserine1378 def: "Protein MAP1B_HUMAN with the residue 1378 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067892 name: MAP1B_HUMAN-Phosphoserine1387 def: "Protein MAP1B_HUMAN with the residue 1387 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067893 name: MAP1B_HUMAN-Phosphoserine1389 def: "Protein MAP1B_HUMAN with the residue 1389 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067894 name: MAP1B_HUMAN-Phosphoserine1396 def: "Protein MAP1B_HUMAN with the residue 1396 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067895 name: MAP1B_HUMAN-Phosphoserine1400 def: "Protein MAP1B_HUMAN with the residue 1400 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067896 name: MAP1B_HUMAN-Phosphoserine1408 def: "Protein MAP1B_HUMAN with the residue 1408 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067897 name: MAP1B_HUMAN-Phosphoserine1427 def: "Protein MAP1B_HUMAN with the residue 1427 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067898 name: MAP1B_HUMAN-Phosphoserine1438 def: "Protein MAP1B_HUMAN with the residue 1438 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067899 name: MAP1B_HUMAN-Phosphoserine1443 def: "Protein MAP1B_HUMAN with the residue 1443 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067900 name: MAP1B_HUMAN-Phosphoserine1501 def: "Protein MAP1B_HUMAN with the residue 1501 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067901 name: MAP1B_HUMAN-Phosphoserine1618 def: "Protein MAP1B_HUMAN with the residue 1618 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067902 name: MAP1B_HUMAN-Phosphoserine1620 def: "Protein MAP1B_HUMAN with the residue 1620 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067903 name: MAP1B_HUMAN-Phosphoserine1625 def: "Protein MAP1B_HUMAN with the residue 1625 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067904 name: MAP1B_HUMAN-Phosphothreonine1633 def: "Protein MAP1B_HUMAN with the residue 1633 substituted with Phosphothreonine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067905 name: MAP1B_HUMAN-Phosphotyrosine1762 def: "Protein MAP1B_HUMAN with the residue 1762 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067906 name: MAP1B_HUMAN-Phosphoserine1772 def: "Protein MAP1B_HUMAN with the residue 1772 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067907 name: MAP1B_HUMAN-Phosphoserine1779 def: "Protein MAP1B_HUMAN with the residue 1779 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067908 name: MAP1B_HUMAN-Phosphoserine1782 def: "Protein MAP1B_HUMAN with the residue 1782 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067909 name: MAP1B_HUMAN-Phosphoserine1785 def: "Protein MAP1B_HUMAN with the residue 1785 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067910 name: MAP1B_HUMAN-Phosphothreonine1788 def: "Protein MAP1B_HUMAN with the residue 1788 substituted with Phosphothreonine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067911 name: MAP1B_HUMAN-Phosphoserine1793 def: "Protein MAP1B_HUMAN with the residue 1793 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067912 name: MAP1B_HUMAN-Phosphotyrosine1796 def: "Protein MAP1B_HUMAN with the residue 1796 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067913 name: MAP1B_HUMAN-Phosphoserine1797 def: "Protein MAP1B_HUMAN with the residue 1797 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067914 name: MAP1B_HUMAN-Phosphoserine1817 def: "Protein MAP1B_HUMAN with the residue 1817 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067915 name: MAP1B_HUMAN-Phosphoserine1819 def: "Protein MAP1B_HUMAN with the residue 1819 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067916 name: MAP1B_HUMAN-Phosphotyrosine1830 def: "Protein MAP1B_HUMAN with the residue 1830 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067917 name: MAP1B_HUMAN-Phosphotyrosine1870 def: "Protein MAP1B_HUMAN with the residue 1870 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067918 name: MAP1B_HUMAN-Phosphotyrosine1872 def: "Protein MAP1B_HUMAN with the residue 1872 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067919 name: MAP1B_HUMAN-Phosphoserine1881 def: "Protein MAP1B_HUMAN with the residue 1881 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067920 name: MAP1B_HUMAN-Phosphotyrosine1904 def: "Protein MAP1B_HUMAN with the residue 1904 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067921 name: MAP1B_HUMAN-Phosphotyrosine1905 def: "Protein MAP1B_HUMAN with the residue 1905 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067922 name: MAP1B_HUMAN-Phosphoserine1915 def: "Protein MAP1B_HUMAN with the residue 1915 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067923 name: MAP1B_HUMAN-Phosphothreonine1932 def: "Protein MAP1B_HUMAN with the residue 1932 substituted with Phosphothreonine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067924 name: MAP1B_HUMAN-Phosphotyrosine1938 def: "Protein MAP1B_HUMAN with the residue 1938 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067925 name: MAP1B_HUMAN-Phosphotyrosine1940 def: "Protein MAP1B_HUMAN with the residue 1940 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067926 name: MAP1B_HUMAN-Phosphothreonine1949 def: "Protein MAP1B_HUMAN with the residue 1949 substituted with Phosphothreonine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067927 name: MAP1B_HUMAN-Phosphotyrosine1957 def: "Protein MAP1B_HUMAN with the residue 1957 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067928 name: MAP1B_HUMAN-Phosphotyrosine1974 def: "Protein MAP1B_HUMAN with the residue 1974 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067929 name: MAP1B_HUMAN-Phosphotyrosine2025 def: "Protein MAP1B_HUMAN with the residue 2025 substituted with Phosphotyrosine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067930 name: MAP1B_HUMAN-Phosphothreonine2034 def: "Protein MAP1B_HUMAN with the residue 2034 substituted with Phosphothreonine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067931 name: MAP1B_HUMAN-Phosphoserine2072 def: "Protein MAP1B_HUMAN with the residue 2072 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067932 name: MAP1B_HUMAN-Phosphoserine2098 def: "Protein MAP1B_HUMAN with the residue 2098 substituted with Phosphoserine" [UniProtKB:P46821] comment: By similarity xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067933 name: MAP1B_HUMAN-Phosphoserine2209 def: "Protein MAP1B_HUMAN with the residue 2209 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067934 name: MAP1B_HUMAN-Phosphoserine2211 def: "Protein MAP1B_HUMAN with the residue 2211 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067935 name: MAP1B_HUMAN-Phosphoserine2289 def: "Protein MAP1B_HUMAN with the residue 2289 substituted with Phosphoserine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067936 name: MAP1B_HUMAN-Phosphothreonine2334 def: "Protein MAP1B_HUMAN with the residue 2334 substituted with Phosphothreonine" [UniProtKB:P46821] xref: UniProtKB:P46821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055380 ! MAP1B_HUMAN [Term] id: CCO:B0067937 name: MAP4_HUMAN-N-acetylalanine2 def: "Protein MAP4_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067938 name: MAP4_HUMAN-Phosphoserine94 def: "Protein MAP4_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067939 name: MAP4_HUMAN-Phosphothreonine96 def: "Protein MAP4_HUMAN with the residue 96 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067940 name: MAP4_HUMAN-Phosphothreonine97 def: "Protein MAP4_HUMAN with the residue 97 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067941 name: MAP4_HUMAN-Phosphoserine99 def: "Protein MAP4_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067942 name: MAP4_HUMAN-Phosphoserine197 def: "Protein MAP4_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067943 name: MAP4_HUMAN-Phosphoserine202 def: "Protein MAP4_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067944 name: MAP4_HUMAN-Phosphoserine253 def: "Protein MAP4_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:P27816] comment: By similarity xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067945 name: MAP4_HUMAN-Phosphoserine280 def: "Protein MAP4_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067946 name: MAP4_HUMAN-Phosphothreonine282 def: "Protein MAP4_HUMAN with the residue 282 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067947 name: MAP4_HUMAN-Phosphothreonine287 def: "Protein MAP4_HUMAN with the residue 287 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067948 name: MAP4_HUMAN-Phosphothreonine380 def: "Protein MAP4_HUMAN with the residue 380 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067949 name: MAP4_HUMAN-Phosphoserine384 def: "Protein MAP4_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067950 name: MAP4_HUMAN-Phosphothreonine484 def: "Protein MAP4_HUMAN with the residue 484 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067951 name: MAP4_HUMAN-Phosphoserine507 def: "Protein MAP4_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067952 name: MAP4_HUMAN-Phosphoserine510 def: "Protein MAP4_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067953 name: MAP4_HUMAN-Phosphothreonine521 def: "Protein MAP4_HUMAN with the residue 521 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067954 name: MAP4_HUMAN-Phosphothreonine526 def: "Protein MAP4_HUMAN with the residue 526 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067955 name: MAP4_HUMAN-Phosphothreonine571 def: "Protein MAP4_HUMAN with the residue 571 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067956 name: MAP4_HUMAN-Phosphoserine609 def: "Protein MAP4_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067957 name: MAP4_HUMAN-Phosphoserine624 def: "Protein MAP4_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:P27816] comment: By similarity xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067958 name: MAP4_HUMAN-Phosphothreonine627 def: "Protein MAP4_HUMAN with the residue 627 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067959 name: MAP4_HUMAN-Phosphoserine636 def: "Protein MAP4_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067960 name: MAP4_HUMAN-Phosphoserine643 def: "Protein MAP4_HUMAN with the residue 643 substituted with Phosphoserine" [UniProtKB:P27816] comment: By similarity xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067961 name: MAP4_HUMAN-Phosphoserine656 def: "Protein MAP4_HUMAN with the residue 656 substituted with Phosphoserine" [UniProtKB:P27816] comment: By similarity xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067962 name: MAP4_HUMAN-Phosphoserine696 def: "Protein MAP4_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067963 name: MAP4_HUMAN-Phosphoserine742 def: "Protein MAP4_HUMAN with the residue 742 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067964 name: MAP4_HUMAN-Phosphoserine745 def: "Protein MAP4_HUMAN with the residue 745 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067965 name: MAP4_HUMAN-Phosphoserine760 def: "Protein MAP4_HUMAN with the residue 760 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067966 name: MAP4_HUMAN-Phosphoserine764 def: "Protein MAP4_HUMAN with the residue 764 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067967 name: MAP4_HUMAN-Phosphoserine768 def: "Protein MAP4_HUMAN with the residue 768 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067968 name: MAP4_HUMAN-Phosphoserine787 def: "Protein MAP4_HUMAN with the residue 787 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067969 name: MAP4_HUMAN-Phosphoserine793 def: "Protein MAP4_HUMAN with the residue 793 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067970 name: MAP4_HUMAN-Phosphothreonine811 def: "Protein MAP4_HUMAN with the residue 811 substituted with Phosphothreonine" [UniProtKB:P27816] comment: By similarity xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067971 name: MAP4_HUMAN-Phosphoserine825 def: "Protein MAP4_HUMAN with the residue 825 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067972 name: MAP4_HUMAN-Phosphoserine827 def: "Protein MAP4_HUMAN with the residue 827 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067973 name: MAP4_HUMAN-Phosphothreonine828 def: "Protein MAP4_HUMAN with the residue 828 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067974 name: MAP4_HUMAN-Phosphothreonine874 def: "Protein MAP4_HUMAN with the residue 874 substituted with Phosphothreonine" [UniProtKB:P27816] comment: By similarity xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067975 name: MAP4_HUMAN-Phosphoserine899 def: "Protein MAP4_HUMAN with the residue 899 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067976 name: MAP4_HUMAN-Phosphoserine915 def: "Protein MAP4_HUMAN with the residue 915 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067977 name: MAP4_HUMAN-Phosphothreonine917 def: "Protein MAP4_HUMAN with the residue 917 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067978 name: MAP4_HUMAN-Phosphothreonine925 def: "Protein MAP4_HUMAN with the residue 925 substituted with Phosphothreonine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067979 name: MAP4_HUMAN-Phosphoserine928 def: "Protein MAP4_HUMAN with the residue 928 substituted with Phosphoserine" [UniProtKB:P27816] comment: By similarity xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067980 name: MAP4_HUMAN-Phosphoserine1000 def: "Protein MAP4_HUMAN with the residue 1000 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067981 name: MAP4_HUMAN-Phosphotyrosine1001 def: "Protein MAP4_HUMAN with the residue 1001 substituted with Phosphotyrosine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067982 name: MAP4_HUMAN-Phosphoserine1073 def: "Protein MAP4_HUMAN with the residue 1073 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067983 name: MAP4_HUMAN-Phosphoserine1151 def: "Protein MAP4_HUMAN with the residue 1151 substituted with Phosphoserine" [UniProtKB:P27816] xref: UniProtKB:P27816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:B0067984 name: MAPK2_HUMAN-Phosphotyrosine63 def: "Protein MAPK2_HUMAN with the residue 63 substituted with Phosphotyrosine" [UniProtKB:P49137] xref: UniProtKB:P49137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:B0067985 name: MAPK2_HUMAN-Phosphoserine328 def: "Protein MAPK2_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P49137] comment: by autocatalysis; By similarity xref: UniProtKB:P49137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:B0067986 name: MAPK2_HUMAN-Phosphothreonine334 def: "Protein MAPK2_HUMAN with the residue 334 substituted with Phosphothreonine" [UniProtKB:P49137] comment: by MAPK; By similarity xref: UniProtKB:P49137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:B0067987 name: MAPK2_HUMAN-Phosphothreonine338 def: "Protein MAPK2_HUMAN with the residue 338 substituted with Phosphothreonine" [UniProtKB:P49137] comment: By similarity xref: UniProtKB:P49137 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:B0067988 name: MARE2_HUMAN-Phosphoserine208 def: "Protein MARE2_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q15555] xref: UniProtKB:Q15555 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000754 ! microtubule cytoskeleton relationship: transformation_of CCO:B0001811 ! MARE2_HUMAN [Term] id: CCO:B0067989 name: MARK1_HUMAN-Phosphoserine588 def: "Protein MARK1_HUMAN with the residue 588 substituted with Phosphoserine" [UniProtKB:Q9P0L2] xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0067990 name: MARK1_HUMAN-Phosphothreonine596 def: "Protein MARK1_HUMAN with the residue 596 substituted with Phosphothreonine" [UniProtKB:Q9P0L2] xref: UniProtKB:Q9P0L2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:B0067991 name: MARK2_HUMAN-Phosphothreonine42 def: "Protein MARK2_HUMAN with the residue 42 substituted with Phosphothreonine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0067992 name: MARK2_HUMAN-Phosphoserine576 def: "Protein MARK2_HUMAN with the residue 576 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0067993 name: MARK2_HUMAN-Phosphoserine621 def: "Protein MARK2_HUMAN with the residue 621 substituted with Phosphoserine" [UniProtKB:Q7KZI7] xref: UniProtKB:Q7KZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:B0067994 name: MARK3_HUMAN-Phosphoserine563 def: "Protein MARK3_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0067995 name: MARK3_HUMAN-Phosphoserine566 def: "Protein MARK3_HUMAN with the residue 566 substituted with Phosphoserine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0067996 name: MARK3_HUMAN-Phosphothreonine572 def: "Protein MARK3_HUMAN with the residue 572 substituted with Phosphothreonine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0067997 name: MARK3_HUMAN-Phosphothreonine614 def: "Protein MARK3_HUMAN with the residue 614 substituted with Phosphothreonine" [UniProtKB:P27448] xref: UniProtKB:P27448 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:B0067998 name: MAST2_HUMAN-Phosphoserine74 def: "Protein MAST2_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q6P0Q8] xref: UniProtKB:Q6P0Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004211 ! phosphatase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056876 ! MAST2_HUMAN [Term] id: CCO:B0067999 name: MAST2_HUMAN-Phosphoserine151 def: "Protein MAST2_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q6P0Q8] comment: By similarity xref: UniProtKB:Q6P0Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056876 ! MAST2_HUMAN [Term] id: CCO:B0068000 name: MAST2_HUMAN-Phosphoserine900 def: "Protein MAST2_HUMAN with the residue 900 substituted with Phosphoserine" [UniProtKB:Q6P0Q8] xref: UniProtKB:Q6P0Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056876 ! MAST2_HUMAN [Term] id: CCO:B0068001 name: MAST2_HUMAN-Phosphoserine1503 def: "Protein MAST2_HUMAN with the residue 1503 substituted with Phosphoserine" [UniProtKB:Q6P0Q8] xref: UniProtKB:Q6P0Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056876 ! MAST2_HUMAN [Term] id: CCO:B0068002 name: MAST2_HUMAN-Phosphothreonine1508 def: "Protein MAST2_HUMAN with the residue 1508 substituted with Phosphothreonine" [UniProtKB:Q6P0Q8] xref: UniProtKB:Q6P0Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056876 ! MAST2_HUMAN [Term] id: CCO:B0068003 name: MATN2_HUMAN-Phosphoserine894 def: "Protein MATN2_HUMAN with the residue 894 substituted with Phosphoserine" [UniProtKB:O00339] xref: UniProtKB:O00339 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030003 ! MATN2_HUMAN [Term] id: CCO:B0068004 name: MATN2_HUMAN-Phosphothreonine895 def: "Protein MATN2_HUMAN with the residue 895 substituted with Phosphothreonine" [UniProtKB:O00339] xref: UniProtKB:O00339 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: transformation_of CCO:B0030003 ! MATN2_HUMAN [Term] id: CCO:B0068005 name: MATR3_HUMAN-Phosphoserine533 def: "Protein MATR3_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:P43243] xref: UniProtKB:P43243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:B0068006 name: MAVS_HUMAN-Phosphothreonine147 def: "Protein MAVS_HUMAN with the residue 147 substituted with Phosphothreonine" [UniProtKB:Q7Z434] comment: By similarity xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068007 name: MAVS_HUMAN-Phosphoserine152 def: "Protein MAVS_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068008 name: MAVS_HUMAN-Phosphoserine157 def: "Protein MAVS_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068009 name: MAVS_HUMAN-Phosphothreonine163 def: "Protein MAVS_HUMAN with the residue 163 substituted with Phosphothreonine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068010 name: MAVS_HUMAN-Phosphoserine165 def: "Protein MAVS_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068011 name: MAVS_HUMAN-Phosphoserine222 def: "Protein MAVS_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068012 name: MAVS_HUMAN-Phosphoserine233 def: "Protein MAVS_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068013 name: MAVS_HUMAN-Phosphothreonine234 def: "Protein MAVS_HUMAN with the residue 234 substituted with Phosphothreonine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068014 name: MAVS_HUMAN-Phosphoserine253 def: "Protein MAVS_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068015 name: MAVS_HUMAN-Phosphoserine258 def: "Protein MAVS_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q7Z434] xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068016 name: MAVS_HUMAN-Phosphoserine366 def: "Protein MAVS_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q7Z434] comment: By similarity xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068017 name: MAVS_HUMAN-Phosphoserine373 def: "Protein MAVS_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:Q7Z434] comment: By similarity xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068018 name: MAVS_HUMAN-Phosphoserine375 def: "Protein MAVS_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:Q7Z434] comment: By similarity xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068019 name: MAVS_HUMAN-Phosphothreonine398 def: "Protein MAVS_HUMAN with the residue 398 substituted with Phosphothreonine" [UniProtKB:Q7Z434] comment: By similarity xref: UniProtKB:Q7Z434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: transformation_of CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:B0068020 name: MBB1A_HUMAN-Phosphoserine11 def: "Protein MBB1A_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068021 name: MBB1A_HUMAN-Phosphotyrosine60 def: "Protein MBB1A_HUMAN with the residue 60 substituted with Phosphotyrosine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068022 name: MBB1A_HUMAN-Phosphoserine775 def: "Protein MBB1A_HUMAN with the residue 775 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068023 name: MBB1A_HUMAN-Phosphoserine1159 def: "Protein MBB1A_HUMAN with the residue 1159 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068024 name: MBB1A_HUMAN-Phosphoserine1163 def: "Protein MBB1A_HUMAN with the residue 1163 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068025 name: MBB1A_HUMAN-Phosphoserine1166 def: "Protein MBB1A_HUMAN with the residue 1166 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068026 name: MBB1A_HUMAN-Phosphoserine1186 def: "Protein MBB1A_HUMAN with the residue 1186 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068027 name: MBB1A_HUMAN-Phosphothreonine1190 def: "Protein MBB1A_HUMAN with the residue 1190 substituted with Phosphothreonine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000406 ! DNA-directed DNA polymerase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001645 ! NLS-dependent protein nuclear import complex relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068028 name: MBB1A_HUMAN-Phosphothreonine1196 def: "Protein MBB1A_HUMAN with the residue 1196 substituted with Phosphothreonine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068029 name: MBB1A_HUMAN-Phosphoserine1207 def: "Protein MBB1A_HUMAN with the residue 1207 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068030 name: MBB1A_HUMAN-Phosphoserine1241 def: "Protein MBB1A_HUMAN with the residue 1241 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068031 name: MBB1A_HUMAN-Phosphothreonine1244 def: "Protein MBB1A_HUMAN with the residue 1244 substituted with Phosphothreonine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068032 name: MBB1A_HUMAN-Phosphoserine1248 def: "Protein MBB1A_HUMAN with the residue 1248 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068033 name: MBB1A_HUMAN-Phosphoserine1267 def: "Protein MBB1A_HUMAN with the residue 1267 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068034 name: MBB1A_HUMAN-Phosphoserine1290 def: "Protein MBB1A_HUMAN with the residue 1290 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068035 name: MBB1A_HUMAN-Phosphoserine1293 def: "Protein MBB1A_HUMAN with the residue 1293 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068036 name: MBB1A_HUMAN-Phosphoserine1303 def: "Protein MBB1A_HUMAN with the residue 1303 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068037 name: MBB1A_HUMAN-Phosphoserine1308 def: "Protein MBB1A_HUMAN with the residue 1308 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068038 name: MBB1A_HUMAN-Phosphoserine1314 def: "Protein MBB1A_HUMAN with the residue 1314 substituted with Phosphoserine" [UniProtKB:Q9BQG0] xref: UniProtKB:Q9BQG0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058481 ! MBB1A_HUMAN [Term] id: CCO:B0068039 name: MBD1_HUMAN-Phosphoserine391 def: "Protein MBD1_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q9UIS9] xref: UniProtKB:Q9UIS9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:B0068040 name: MBD1_HUMAN-Phosphoserine399 def: "Protein MBD1_HUMAN with the residue 399 substituted with Phosphoserine" [UniProtKB:Q9UIS9] xref: UniProtKB:Q9UIS9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:B0068041 name: MBD2_HUMAN-Phosphoserine181 def: "Protein MBD2_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q9UBB5] xref: UniProtKB:Q9UBB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059065 ! MBD2_HUMAN [Term] id: CCO:B0068042 name: MBD2_HUMAN-Phosphoserine407 def: "Protein MBD2_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q9UBB5] xref: UniProtKB:Q9UBB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000287 ! satellite DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001837 ! methyl-CpG binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059065 ! MBD2_HUMAN [Term] id: CCO:B0068043 name: MBIP1_HUMAN-Phosphoserine91 def: "Protein MBIP1_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q9NS73] xref: UniProtKB:Q9NS73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005271 ! MBIP1_HUMAN [Term] id: CCO:B0068044 name: MCA3_HUMAN-N-acetylalanine2 def: "Protein MCA3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O43324] xref: UniProtKB:O43324 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054472 ! MCA3_HUMAN [Term] id: CCO:B0068045 name: MCAF1_HUMAN-Phosphoserine113 def: "Protein MCAF1_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q6VMQ6] xref: UniProtKB:Q6VMQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056962 ! MCAF1_HUMAN [Term] id: CCO:B0068046 name: MCAF1_HUMAN-Phosphothreonine118 def: "Protein MCAF1_HUMAN with the residue 118 substituted with Phosphothreonine" [UniProtKB:Q6VMQ6] xref: UniProtKB:Q6VMQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056962 ! MCAF1_HUMAN [Term] id: CCO:B0068047 name: MCAF1_HUMAN-Phosphoserine473 def: "Protein MCAF1_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:Q6VMQ6] xref: UniProtKB:Q6VMQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056962 ! MCAF1_HUMAN [Term] id: CCO:B0068048 name: MCAF1_HUMAN-Phosphoserine477 def: "Protein MCAF1_HUMAN with the residue 477 substituted with Phosphoserine" [UniProtKB:Q6VMQ6] xref: UniProtKB:Q6VMQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056962 ! MCAF1_HUMAN [Term] id: CCO:B0068049 name: MCAF1_HUMAN-Phosphoserine496 def: "Protein MCAF1_HUMAN with the residue 496 substituted with Phosphoserine" [UniProtKB:Q6VMQ6] xref: UniProtKB:Q6VMQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056962 ! MCAF1_HUMAN [Term] id: CCO:B0068050 name: MCAF1_HUMAN-Phosphoserine673 def: "Protein MCAF1_HUMAN with the residue 673 substituted with Phosphoserine" [UniProtKB:Q6VMQ6] xref: UniProtKB:Q6VMQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056962 ! MCAF1_HUMAN [Term] id: CCO:B0068051 name: MCAF1_HUMAN-Phosphoserine899 def: "Protein MCAF1_HUMAN with the residue 899 substituted with Phosphoserine" [UniProtKB:Q6VMQ6] xref: UniProtKB:Q6VMQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056962 ! MCAF1_HUMAN [Term] id: CCO:B0068052 name: MCAT_HUMAN-N6-acetyllysine148 def: "Protein MCAT_HUMAN with the residue 148 substituted with N6-acetyllysine" [UniProtKB:O43772] comment: By similarity xref: UniProtKB:O43772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054520 ! MCAT_HUMAN [Term] id: CCO:B0068053 name: MCAT_HUMAN-N6-acetyllysine244 def: "Protein MCAT_HUMAN with the residue 244 substituted with N6-acetyllysine" [UniProtKB:O43772] comment: By similarity xref: UniProtKB:O43772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054520 ! MCAT_HUMAN [Term] id: CCO:B0068054 name: MCF2L_HUMAN-Phosphoserine975 def: "Protein MCF2L_HUMAN with the residue 975 substituted with Phosphoserine" [UniProtKB:O15068] xref: UniProtKB:O15068 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054403 ! MCF2L_HUMAN [Term] id: CCO:B0068055 name: MCF2_HUMAN-Phosphoserine742 def: "Protein MCF2_HUMAN with the residue 742 substituted with Phosphoserine" [UniProtKB:P10911] xref: UniProtKB:P10911 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054981 ! MCF2_HUMAN [Term] id: CCO:B0068056 name: MCH_HUMAN-Isoleucine amide143 def: "Protein MCH_HUMAN with the residue 143 substituted with Isoleucine amide" [UniProtKB:P20382] comment: By similarity xref: UniProtKB:P20382 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055120 ! MCH_HUMAN [Term] id: CCO:B0068057 name: MCL1_HUMAN-Phosphoserine121 def: "Protein MCL1_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q07820] xref: UniProtKB:Q07820 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055785 ! MCL1_HUMAN [Term] id: CCO:B0068058 name: MCL1_HUMAN-Phosphothreonine163 def: "Protein MCL1_HUMAN with the residue 163 substituted with Phosphothreonine" [UniProtKB:Q07820] comment: by MAPK; xref: UniProtKB:Q07820 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002724 ! protein channel activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055785 ! MCL1_HUMAN [Term] id: CCO:B0068059 name: MCLN1_HUMAN-Phosphoserine10 def: "Protein MCLN1_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:Q9GZU1] comment: By similarity xref: UniProtKB:Q9GZU1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028808 ! MCLN1_HUMAN [Term] id: CCO:B0068060 name: MCLN1_HUMAN-Phosphothreonine34 def: "Protein MCLN1_HUMAN with the residue 34 substituted with Phosphothreonine" [UniProtKB:Q9GZU1] comment: By similarity xref: UniProtKB:Q9GZU1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028808 ! MCLN1_HUMAN [Term] id: CCO:B0068061 name: MCLN1_HUMAN-Phosphoserine547 def: "Protein MCLN1_HUMAN with the residue 547 substituted with Phosphoserine" [UniProtKB:Q9GZU1] comment: By similarity xref: UniProtKB:Q9GZU1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001524 ! cation channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000348 ! lysosomal membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001340 ! late endosome membrane relationship: transformation_of CCO:B0028808 ! MCLN1_HUMAN [Term] id: CCO:B0068062 name: MCM2_HUMAN-Phosphoserine381 def: "Protein MCM2_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:P49736] xref: UniProtKB:P49736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:B0068063 name: MCM3A_HUMAN-Phosphoserine557 def: "Protein MCM3A_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:O60318] xref: UniProtKB:O60318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054547 ! MCM3A_HUMAN [Term] id: CCO:B0068064 name: MCM4_HUMAN-Phosphoserine31 def: "Protein MCM4_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0068065 name: MCM4_HUMAN-Phosphoserine34 def: "Protein MCM4_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0068066 name: MCM4_HUMAN-Phosphothreonine102 def: "Protein MCM4_HUMAN with the residue 102 substituted with Phosphothreonine" [UniProtKB:P33991] xref: UniProtKB:P33991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:B0068067 name: MCM7_HUMAN-Phosphoserine121 def: "Protein MCM7_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:P33993] xref: UniProtKB:P33993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001589 ! MCM7_HUMAN [Term] id: CCO:B0068068 name: MCM7_HUMAN-Phosphoserine500 def: "Protein MCM7_HUMAN with the residue 500 substituted with Phosphoserine" [UniProtKB:P33993] xref: UniProtKB:P33993 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001589 ! MCM7_HUMAN [Term] id: CCO:B0068069 name: MCTP2_HUMAN-Phosphothreonine144 def: "Protein MCTP2_HUMAN with the residue 144 substituted with Phosphothreonine" [UniProtKB:Q6DN12] xref: UniProtKB:Q6DN12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056726 ! MCTP2_HUMAN [Term] id: CCO:B0068070 name: MCTP2_HUMAN-Phosphoserine145 def: "Protein MCTP2_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:Q6DN12] xref: UniProtKB:Q6DN12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001667 ! calcium-dependent phospholipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056726 ! MCTP2_HUMAN [Term] id: CCO:B0068071 name: MCTS1_HUMAN-Phosphothreonine81 def: "Protein MCTS1_HUMAN with the residue 81 substituted with Phosphothreonine" [UniProtKB:Q9ULC4] comment: by MAPK1 and MAPK3; xref: UniProtKB:Q9ULC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002223 ! MCTS1_HUMAN [Term] id: CCO:B0068072 name: MCTS1_HUMAN-Phosphoserine118 def: "Protein MCTS1_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q9ULC4] comment: by CDC2; xref: UniProtKB:Q9ULC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002223 ! MCTS1_HUMAN [Term] id: CCO:B0068073 name: MD12L_HUMAN-Phosphothreonine462 def: "Protein MD12L_HUMAN with the residue 462 substituted with Phosphothreonine" [UniProtKB:Q86YW9] xref: UniProtKB:Q86YW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038407 ! MD12L_HUMAN [Term] id: CCO:B0068074 name: MD12L_HUMAN-Phosphothreonine474 def: "Protein MD12L_HUMAN with the residue 474 substituted with Phosphothreonine" [UniProtKB:Q86YW9] xref: UniProtKB:Q86YW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038407 ! MD12L_HUMAN [Term] id: CCO:B0068075 name: MD12L_HUMAN-Phosphotyrosine484 def: "Protein MD12L_HUMAN with the residue 484 substituted with Phosphotyrosine" [UniProtKB:Q86YW9] xref: UniProtKB:Q86YW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038407 ! MD12L_HUMAN [Term] id: CCO:B0068076 name: MD12L_HUMAN-Phosphoserine1751 def: "Protein MD12L_HUMAN with the residue 1751 substituted with Phosphoserine" [UniProtKB:Q86YW9] comment: By similarity xref: UniProtKB:Q86YW9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038407 ! MD12L_HUMAN [Term] id: CCO:B0068077 name: MD1L1_HUMAN-Phosphoserine16 def: "Protein MD1L1_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q9Y6D9] xref: UniProtKB:Q9Y6D9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002264 ! MD1L1_HUMAN [Term] id: CCO:B0068078 name: MDC1_HUMAN-Phosphoserine176 def: "Protein MDC1_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068079 name: MDC1_HUMAN-Phosphoserine299 def: "Protein MDC1_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068080 name: MDC1_HUMAN-Phosphothreonine301 def: "Protein MDC1_HUMAN with the residue 301 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068081 name: MDC1_HUMAN-Phosphothreonine341 def: "Protein MDC1_HUMAN with the residue 341 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068082 name: MDC1_HUMAN-Phosphoserine394 def: "Protein MDC1_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068083 name: MDC1_HUMAN-Phosphoserine397 def: "Protein MDC1_HUMAN with the residue 397 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068084 name: MDC1_HUMAN-Phosphothreonine449 def: "Protein MDC1_HUMAN with the residue 449 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068085 name: MDC1_HUMAN-Phosphoserine504 def: "Protein MDC1_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068086 name: MDC1_HUMAN-Phosphoserine793 def: "Protein MDC1_HUMAN with the residue 793 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068087 name: MDC1_HUMAN-Phosphoserine1033 def: "Protein MDC1_HUMAN with the residue 1033 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068088 name: MDC1_HUMAN-Phosphothreonine1198 def: "Protein MDC1_HUMAN with the residue 1198 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068089 name: MDC1_HUMAN-Phosphoserine1212 def: "Protein MDC1_HUMAN with the residue 1212 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068090 name: MDC1_HUMAN-Phosphoserine1400 def: "Protein MDC1_HUMAN with the residue 1400 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068091 name: MDC1_HUMAN-Phosphothreonine1444 def: "Protein MDC1_HUMAN with the residue 1444 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068092 name: MDC1_HUMAN-Phosphothreonine1466 def: "Protein MDC1_HUMAN with the residue 1466 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068093 name: MDC1_HUMAN-Phosphothreonine1589 def: "Protein MDC1_HUMAN with the residue 1589 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068094 name: MDC1_HUMAN-Phosphothreonine1601 def: "Protein MDC1_HUMAN with the residue 1601 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068095 name: MDC1_HUMAN-Phosphoserine1604 def: "Protein MDC1_HUMAN with the residue 1604 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068096 name: MDC1_HUMAN-Phosphothreonine1608 def: "Protein MDC1_HUMAN with the residue 1608 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068097 name: MDC1_HUMAN-Phosphothreonine1630 def: "Protein MDC1_HUMAN with the residue 1630 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068098 name: MDC1_HUMAN-Phosphothreonine1649 def: "Protein MDC1_HUMAN with the residue 1649 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068099 name: MDC1_HUMAN-Phosphothreonine1664 def: "Protein MDC1_HUMAN with the residue 1664 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068100 name: MDC1_HUMAN-Phosphothreonine1671 def: "Protein MDC1_HUMAN with the residue 1671 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068101 name: MDC1_HUMAN-Phosphoserine1681 def: "Protein MDC1_HUMAN with the residue 1681 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068102 name: MDC1_HUMAN-Phosphothreonine1696 def: "Protein MDC1_HUMAN with the residue 1696 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068103 name: MDC1_HUMAN-Phosphothreonine1697 def: "Protein MDC1_HUMAN with the residue 1697 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068104 name: MDC1_HUMAN-Phosphoserine1702 def: "Protein MDC1_HUMAN with the residue 1702 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068105 name: MDC1_HUMAN-Phosphoserine1711 def: "Protein MDC1_HUMAN with the residue 1711 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068106 name: MDC1_HUMAN-Phosphoserine1775 def: "Protein MDC1_HUMAN with the residue 1775 substituted with Phosphoserine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068107 name: MDC1_HUMAN-Phosphothreonine1858 def: "Protein MDC1_HUMAN with the residue 1858 substituted with Phosphothreonine" [UniProtKB:Q14676] xref: UniProtKB:Q14676 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:B0068108 name: MDFIC_HUMAN-Phosphoserine249 def: "Protein MDFIC_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:Q9P1T7] xref: UniProtKB:Q9P1T7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059043 ! MDFIC_HUMAN [Term] id: CCO:B0068109 name: MDFIC_HUMAN-Phosphoserine252 def: "Protein MDFIC_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:Q9P1T7] xref: UniProtKB:Q9P1T7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059043 ! MDFIC_HUMAN [Term] id: CCO:B0068110 name: MDHC_HUMAN-N-acetylserine2 def: "Protein MDHC_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P40925] xref: UniProtKB:P40925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063181 ! MDHC_HUMAN [Term] id: CCO:B0068111 name: MDHC_HUMAN-Phosphotyrosine210 def: "Protein MDHC_HUMAN with the residue 210 substituted with Phosphotyrosine" [UniProtKB:P40925] comment: By similarity xref: UniProtKB:P40925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000869 ! malic enzyme activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003217 ! malate dehydrogenase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0004321 ! L-malate dehydrogenase activity relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0063181 ! MDHC_HUMAN [Term] id: CCO:B0068112 name: MECP2_HUMAN-Phosphoserine80 def: "Protein MECP2_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:P51608] xref: UniProtKB:P51608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:B0068113 name: MECP2_HUMAN-Phosphoserine116 def: "Protein MECP2_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:P51608] xref: UniProtKB:P51608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:B0068114 name: MECP2_HUMAN-Phosphoserine229 def: "Protein MECP2_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:P51608] comment: By similarity xref: UniProtKB:P51608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:B0068115 name: MECP2_HUMAN-Phosphoserine423 def: "Protein MECP2_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:P51608] comment: By similarity xref: UniProtKB:P51608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:B0068116 name: MECP2_HUMAN-Phosphoserine426 def: "Protein MECP2_HUMAN with the residue 426 substituted with Phosphoserine" [UniProtKB:P51608] xref: UniProtKB:P51608 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:B0068117 name: MED12_HUMAN-Phosphotyrosine166 def: "Protein MED12_HUMAN with the residue 166 substituted with Phosphotyrosine" [UniProtKB:Q93074] xref: UniProtKB:Q93074 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005789 ! MED12_HUMAN [Term] id: CCO:B0068118 name: MED12_HUMAN-Phosphoserine635 def: "Protein MED12_HUMAN with the residue 635 substituted with Phosphoserine" [UniProtKB:Q93074] xref: UniProtKB:Q93074 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005789 ! MED12_HUMAN [Term] id: CCO:B0068119 name: MED13_HUMAN-Phosphoserine504 def: "Protein MED13_HUMAN with the residue 504 substituted with Phosphoserine" [UniProtKB:Q9UHV7] xref: UniProtKB:Q9UHV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005794 ! MED13_HUMAN [Term] id: CCO:B0068120 name: MED13_HUMAN-Phosphothreonine519 def: "Protein MED13_HUMAN with the residue 519 substituted with Phosphothreonine" [UniProtKB:Q9UHV7] xref: UniProtKB:Q9UHV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005794 ! MED13_HUMAN [Term] id: CCO:B0068121 name: MED13_HUMAN-Phosphoserine537 def: "Protein MED13_HUMAN with the residue 537 substituted with Phosphoserine" [UniProtKB:Q9UHV7] xref: UniProtKB:Q9UHV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005794 ! MED13_HUMAN [Term] id: CCO:B0068122 name: MED15_HUMAN-Phosphothreonine603 def: "Protein MED15_HUMAN with the residue 603 substituted with Phosphothreonine" [UniProtKB:Q96RN5] xref: UniProtKB:Q96RN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005790 ! MED15_HUMAN [Term] id: CCO:B0068123 name: MED1_HUMAN-Phosphoserine664 def: "Protein MED1_HUMAN with the residue 664 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0068124 name: MED1_HUMAN-Phosphoserine1207 def: "Protein MED1_HUMAN with the residue 1207 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0068125 name: MED1_HUMAN-Phosphothreonine1215 def: "Protein MED1_HUMAN with the residue 1215 substituted with Phosphothreonine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0068126 name: MED1_HUMAN-Phosphoserine1463 def: "Protein MED1_HUMAN with the residue 1463 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0068127 name: MED1_HUMAN-Phosphoserine1479 def: "Protein MED1_HUMAN with the residue 1479 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0068128 name: MED1_HUMAN-Phosphoserine1481 def: "Protein MED1_HUMAN with the residue 1481 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0068129 name: MED1_HUMAN-Phosphoserine1482 def: "Protein MED1_HUMAN with the residue 1482 substituted with Phosphoserine" [UniProtKB:Q15648] xref: UniProtKB:Q15648 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:B0068130 name: MEF2A_HUMAN-Phosphoserine98 def: "Protein MEF2A_HUMAN with the residue 98 substituted with Phosphoserine" [UniProtKB:Q02078] comment: By similarity xref: UniProtKB:Q02078 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055702 ! MEF2A_HUMAN [Term] id: CCO:B0068131 name: MEF2A_HUMAN-Phosphothreonine108 def: "Protein MEF2A_HUMAN with the residue 108 substituted with Phosphothreonine" [UniProtKB:Q02078] comment: By similarity xref: UniProtKB:Q02078 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055702 ! MEF2A_HUMAN [Term] id: CCO:B0068132 name: MEF2A_HUMAN-Phosphoserine235 def: "Protein MEF2A_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q02078] xref: UniProtKB:Q02078 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055702 ! MEF2A_HUMAN [Term] id: CCO:B0068133 name: MEF2A_HUMAN-Phosphoserine255 def: "Protein MEF2A_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:Q02078] xref: UniProtKB:Q02078 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055702 ! MEF2A_HUMAN [Term] id: CCO:B0068134 name: MEF2A_HUMAN-N6-acetyllysine403 def: "Protein MEF2A_HUMAN with the residue 403 substituted with N6-acetyllysine" [UniProtKB:Q02078] comment: alternate; By similarity xref: UniProtKB:Q02078 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055702 ! MEF2A_HUMAN [Term] id: CCO:B0068135 name: MEF2A_HUMAN-Phosphoserine408 def: "Protein MEF2A_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:Q02078] xref: UniProtKB:Q02078 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055702 ! MEF2A_HUMAN [Term] id: CCO:B0068136 name: MEF2C_HUMAN-Phosphoserine59 def: "Protein MEF2C_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:Q06413] comment: by CK2; By similarity xref: UniProtKB:Q06413 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055768 ! MEF2C_HUMAN [Term] id: CCO:B0068137 name: MEF2C_HUMAN-Phosphoserine396 def: "Protein MEF2C_HUMAN with the residue 396 substituted with Phosphoserine" [UniProtKB:Q06413] xref: UniProtKB:Q06413 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055768 ! MEF2C_HUMAN [Term] id: CCO:B0068138 name: MEF2D_HUMAN-Phosphoserine98 def: "Protein MEF2D_HUMAN with the residue 98 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068139 name: MEF2D_HUMAN-Phosphoserine106 def: "Protein MEF2D_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068140 name: MEF2D_HUMAN-Phosphoserine110 def: "Protein MEF2D_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068141 name: MEF2D_HUMAN-Phosphoserine121 def: "Protein MEF2D_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068142 name: MEF2D_HUMAN-Phosphoserine180 def: "Protein MEF2D_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068143 name: MEF2D_HUMAN-Phosphoserine212 def: "Protein MEF2D_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068144 name: MEF2D_HUMAN-Phosphoserine231 def: "Protein MEF2D_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068145 name: MEF2D_HUMAN-Phosphoserine251 def: "Protein MEF2D_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:Q14814] xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068146 name: MEF2D_HUMAN-N6-acetyllysine439 def: "Protein MEF2D_HUMAN with the residue 439 substituted with N6-acetyllysine" [UniProtKB:Q14814] comment: alternate; xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068147 name: MEF2D_HUMAN-Phosphoserine444 def: "Protein MEF2D_HUMAN with the residue 444 substituted with Phosphoserine" [UniProtKB:Q14814] comment: by CDK5; xref: UniProtKB:Q14814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056017 ! MEF2D_HUMAN [Term] id: CCO:B0068148 name: MERTK_HUMAN-Phosphotyrosine754 def: "Protein MERTK_HUMAN with the residue 754 substituted with Phosphotyrosine" [UniProtKB:Q12866] comment: by autocatalysis; By similarity xref: UniProtKB:Q12866 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0018657 ! MERTK_HUMAN [Term] id: CCO:B0068149 name: MET_HUMAN-Phosphotyrosine1230 def: "Protein MET_HUMAN with the residue 1230 substituted with Phosphotyrosine" [UniProtKB:P08581] xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0068150 name: MET_HUMAN-Phosphotyrosine1234 def: "Protein MET_HUMAN with the residue 1234 substituted with Phosphotyrosine" [UniProtKB:P08581] xref: UniProtKB:P08581 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005438 ! MET_HUMAN [Term] id: CCO:B0068151 name: MFHA1_HUMAN-Phosphotyrosine447 def: "Protein MFHA1_HUMAN with the residue 447 substituted with Phosphotyrosine" [UniProtKB:Q9Y4C4] xref: UniProtKB:Q9Y4C4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059358 ! MFHA1_HUMAN [Term] id: CCO:B0068152 name: MFHA1_HUMAN-Phosphoserine450 def: "Protein MFHA1_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q9Y4C4] xref: UniProtKB:Q9Y4C4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059358 ! MFHA1_HUMAN [Term] id: CCO:B0068153 name: MFHA1_HUMAN-Phosphoserine455 def: "Protein MFHA1_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q9Y4C4] xref: UniProtKB:Q9Y4C4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059358 ! MFHA1_HUMAN [Term] id: CCO:B0068154 name: MFHA1_HUMAN-Phosphoserine468 def: "Protein MFHA1_HUMAN with the residue 468 substituted with Phosphoserine" [UniProtKB:Q9Y4C4] xref: UniProtKB:Q9Y4C4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059358 ! MFHA1_HUMAN [Term] id: CCO:B0068155 name: MGAP_HUMAN-Phosphoserine924 def: "Protein MGAP_HUMAN with the residue 924 substituted with Phosphoserine" [UniProtKB:Q8IWI9] xref: UniProtKB:Q8IWI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057360 ! MGAP_HUMAN [Term] id: CCO:B0068156 name: MGAP_HUMAN-Phosphoserine1208 def: "Protein MGAP_HUMAN with the residue 1208 substituted with Phosphoserine" [UniProtKB:Q8IWI9] xref: UniProtKB:Q8IWI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057360 ! MGAP_HUMAN [Term] id: CCO:B0068157 name: MGAP_HUMAN-Phosphoserine1457 def: "Protein MGAP_HUMAN with the residue 1457 substituted with Phosphoserine" [UniProtKB:Q8IWI9] xref: UniProtKB:Q8IWI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057360 ! MGAP_HUMAN [Term] id: CCO:B0068158 name: MGAP_HUMAN-Phosphoserine1973 def: "Protein MGAP_HUMAN with the residue 1973 substituted with Phosphoserine" [UniProtKB:Q8IWI9] xref: UniProtKB:Q8IWI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057360 ! MGAP_HUMAN [Term] id: CCO:B0068159 name: MGMT_HUMAN-Phosphothreonine10 def: "Protein MGMT_HUMAN with the residue 10 substituted with Phosphothreonine" [UniProtKB:P16455] xref: UniProtKB:P16455 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055052 ! MGMT_HUMAN [Term] id: CCO:B0068160 name: MGMT_HUMAN-Phosphothreonine11 def: "Protein MGMT_HUMAN with the residue 11 substituted with Phosphothreonine" [UniProtKB:P16455] xref: UniProtKB:P16455 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055052 ! MGMT_HUMAN [Term] id: CCO:B0068161 name: MGMT_HUMAN-Phosphoserine201 def: "Protein MGMT_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:P16455] xref: UniProtKB:P16455 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000412 ! methylated-DNA-[protein]-cysteine S-methyltransferase activity relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002339 ! DNA-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0055052 ! MGMT_HUMAN [Term] id: CCO:B0068162 name: MIA3_HUMAN-Phosphothreonine382 def: "Protein MIA3_HUMAN with the residue 382 substituted with Phosphothreonine" [UniProtKB:Q5JRA6] comment: By similarity xref: UniProtKB:Q5JRA6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:B0068163 name: MIA3_HUMAN-Phosphoserine727 def: "Protein MIA3_HUMAN with the residue 727 substituted with Phosphoserine" [UniProtKB:Q5JRA6] xref: UniProtKB:Q5JRA6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:B0068164 name: MIA3_HUMAN-Phosphoserine1727 def: "Protein MIA3_HUMAN with the residue 1727 substituted with Phosphoserine" [UniProtKB:Q5JRA6] comment: By similarity xref: UniProtKB:Q5JRA6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:B0068165 name: MIA3_HUMAN-Phosphoserine1739 def: "Protein MIA3_HUMAN with the residue 1739 substituted with Phosphoserine" [UniProtKB:Q5JRA6] comment: By similarity xref: UniProtKB:Q5JRA6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:B0068166 name: MIA3_HUMAN-Phosphoserine1740 def: "Protein MIA3_HUMAN with the residue 1740 substituted with Phosphoserine" [UniProtKB:Q5JRA6] comment: By similarity xref: UniProtKB:Q5JRA6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:B0068167 name: MIA3_HUMAN-Phosphoserine1892 def: "Protein MIA3_HUMAN with the residue 1892 substituted with Phosphoserine" [UniProtKB:Q5JRA6] comment: By similarity xref: UniProtKB:Q5JRA6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:B0068168 name: MIA3_HUMAN-Phosphoserine1906 def: "Protein MIA3_HUMAN with the residue 1906 substituted with Phosphoserine" [UniProtKB:Q5JRA6] xref: UniProtKB:Q5JRA6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:B0068169 name: MIB2_HUMAN-Phosphothreonine200 def: "Protein MIB2_HUMAN with the residue 200 substituted with Phosphothreonine" [UniProtKB:Q96AX9] xref: UniProtKB:Q96AX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058158 ! MIB2_HUMAN [Term] id: CCO:B0068170 name: MIB2_HUMAN-Phosphoserine202 def: "Protein MIB2_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q96AX9] xref: UniProtKB:Q96AX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: transformation_of CCO:B0058158 ! MIB2_HUMAN [Term] id: CCO:B0068171 name: MICA1_HUMAN-Phosphoserine872 def: "Protein MICA1_HUMAN with the residue 872 substituted with Phosphoserine" [UniProtKB:Q8TDZ2] xref: UniProtKB:Q8TDZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057947 ! MICA1_HUMAN [Term] id: CCO:B0068172 name: MICA1_HUMAN-Phosphoserine875 def: "Protein MICA1_HUMAN with the residue 875 substituted with Phosphoserine" [UniProtKB:Q8TDZ2] xref: UniProtKB:Q8TDZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057947 ! MICA1_HUMAN [Term] id: CCO:B0068173 name: MICA1_HUMAN-Phosphoserine876 def: "Protein MICA1_HUMAN with the residue 876 substituted with Phosphoserine" [UniProtKB:Q8TDZ2] xref: UniProtKB:Q8TDZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000894 ! monooxygenase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0057947 ! MICA1_HUMAN [Term] id: CCO:B0068174 name: MIER1_HUMAN-Phosphoserine146 def: "Protein MIER1_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068175 name: MIER1_HUMAN-Phosphotyrosine179 def: "Protein MIER1_HUMAN with the residue 179 substituted with Phosphotyrosine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068176 name: MIER1_HUMAN-Phosphoserine184 def: "Protein MIER1_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068177 name: MIER1_HUMAN-Phosphoserine190 def: "Protein MIER1_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068178 name: MIER1_HUMAN-Phosphoserine401 def: "Protein MIER1_HUMAN with the residue 401 substituted with Phosphoserine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068179 name: MIER1_HUMAN-Phosphothreonine405 def: "Protein MIER1_HUMAN with the residue 405 substituted with Phosphothreonine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068180 name: MIER1_HUMAN-Phosphoserine407 def: "Protein MIER1_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068181 name: MIER1_HUMAN-Phosphoserine507 def: "Protein MIER1_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068182 name: MIER1_HUMAN-Phosphoserine512 def: "Protein MIER1_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q8N108] xref: UniProtKB:Q8N108 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020321 ! MIER1_HUMAN [Term] id: CCO:B0068183 name: MIER3_HUMAN-Phosphoserine52 def: "Protein MIER3_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q7Z3K6] xref: UniProtKB:Q7Z3K6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057152 ! MIER3_HUMAN [Term] id: CCO:B0068184 name: MIER3_HUMAN-Phosphoserine156 def: "Protein MIER3_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q7Z3K6] xref: UniProtKB:Q7Z3K6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057152 ! MIER3_HUMAN [Term] id: CCO:B0068185 name: MIER3_HUMAN-Phosphoserine168 def: "Protein MIER3_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q7Z3K6] comment: By similarity xref: UniProtKB:Q7Z3K6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057152 ! MIER3_HUMAN [Term] id: CCO:B0068186 name: MIF_HUMAN-Phosphotyrosine37 def: "Protein MIF_HUMAN with the residue 37 substituted with Phosphotyrosine" [UniProtKB:P14174] xref: UniProtKB:P14174 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_function CCO:F0007531 ! phenylpyruvate tautomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: transformation_of CCO:B0055021 ! MIF_HUMAN [Term] id: CCO:B0068187 name: MINK1_HUMAN-Phosphoserine777 def: "Protein MINK1_HUMAN with the residue 777 substituted with Phosphoserine" [UniProtKB:Q8N4C8] xref: UniProtKB:Q8N4C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041947 ! MINK1_HUMAN [Term] id: CCO:B0068188 name: MINT_HUMAN-Phosphoserine43 def: "Protein MINT_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068189 name: MINT_HUMAN-Phosphoserine1194 def: "Protein MINT_HUMAN with the residue 1194 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068190 name: MINT_HUMAN-Phosphoserine1287 def: "Protein MINT_HUMAN with the residue 1287 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068191 name: MINT_HUMAN-Phosphoserine1390 def: "Protein MINT_HUMAN with the residue 1390 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068192 name: MINT_HUMAN-Phosphoserine1392 def: "Protein MINT_HUMAN with the residue 1392 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068193 name: MINT_HUMAN-Phosphothreonine1439 def: "Protein MINT_HUMAN with the residue 1439 substituted with Phosphothreonine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068194 name: MINT_HUMAN-Phosphothreonine1441 def: "Protein MINT_HUMAN with the residue 1441 substituted with Phosphothreonine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068195 name: MINT_HUMAN-Phosphoserine1897 def: "Protein MINT_HUMAN with the residue 1897 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068196 name: MINT_HUMAN-Phosphoserine2366 def: "Protein MINT_HUMAN with the residue 2366 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068197 name: MINT_HUMAN-Phosphothreonine2938 def: "Protein MINT_HUMAN with the residue 2938 substituted with Phosphothreonine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068198 name: MINT_HUMAN-Phosphothreonine2950 def: "Protein MINT_HUMAN with the residue 2950 substituted with Phosphothreonine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068199 name: MINT_HUMAN-Phosphoserine3433 def: "Protein MINT_HUMAN with the residue 3433 substituted with Phosphoserine" [UniProtKB:Q96T58] xref: UniProtKB:Q96T58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:B0068200 name: MIST_HUMAN-Phosphotyrosine69 def: "Protein MIST_HUMAN with the residue 69 substituted with Phosphotyrosine" [UniProtKB:Q7Z7G1] comment: by LYN; By similarity xref: UniProtKB:Q7Z7G1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057213 ! MIST_HUMAN [Term] id: CCO:B0068201 name: MIST_HUMAN-Phosphotyrosine96 def: "Protein MIST_HUMAN with the residue 96 substituted with Phosphotyrosine" [UniProtKB:Q7Z7G1] comment: by LYN; By similarity xref: UniProtKB:Q7Z7G1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057213 ! MIST_HUMAN [Term] id: CCO:B0068202 name: MITF_HUMAN-Phosphothreonine54 def: "Protein MITF_HUMAN with the residue 54 substituted with Phosphothreonine" [UniProtKB:O75030] xref: UniProtKB:O75030 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054595 ! MITF_HUMAN [Term] id: CCO:B0068203 name: MITF_HUMAN-Phosphoserine405 def: "Protein MITF_HUMAN with the residue 405 substituted with Phosphoserine" [UniProtKB:O75030] comment: by GSK3; xref: UniProtKB:O75030 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054595 ! MITF_HUMAN [Term] id: CCO:B0068204 name: MITF_HUMAN-Phosphoserine414 def: "Protein MITF_HUMAN with the residue 414 substituted with Phosphoserine" [UniProtKB:O75030] xref: UniProtKB:O75030 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054595 ! MITF_HUMAN [Term] id: CCO:B0068205 name: MIXL1_HUMAN-Phosphotyrosine20 def: "Protein MIXL1_HUMAN with the residue 20 substituted with Phosphotyrosine" [UniProtKB:Q9H2W2] xref: UniProtKB:Q9H2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058690 ! MIXL1_HUMAN [Term] id: CCO:B0068206 name: MK04_HUMAN-Phosphoserine186 def: "Protein MK04_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:P31152] xref: UniProtKB:P31152 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001582 ! MK04_HUMAN [Term] id: CCO:B0068207 name: MK06_HUMAN-Phosphoserine189 def: "Protein MK06_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q16659] xref: UniProtKB:Q16659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001822 ! MK06_HUMAN [Term] id: CCO:B0068208 name: MK06_HUMAN-Phosphoserine386 def: "Protein MK06_HUMAN with the residue 386 substituted with Phosphoserine" [UniProtKB:Q16659] xref: UniProtKB:Q16659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001822 ! MK06_HUMAN [Term] id: CCO:B0068209 name: MK06_HUMAN-Phosphothreonine389 def: "Protein MK06_HUMAN with the residue 389 substituted with Phosphothreonine" [UniProtKB:Q16659] xref: UniProtKB:Q16659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001822 ! MK06_HUMAN [Term] id: CCO:B0068210 name: MK06_HUMAN-Phosphoserine665 def: "Protein MK06_HUMAN with the residue 665 substituted with Phosphoserine" [UniProtKB:Q16659] xref: UniProtKB:Q16659 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001822 ! MK06_HUMAN [Term] id: CCO:B0068211 name: MKL1_HUMAN-Phosphoserine6 def: "Protein MKL1_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q969V6] xref: UniProtKB:Q969V6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058143 ! MKL1_HUMAN [Term] id: CCO:B0068212 name: MKL1_HUMAN-Phosphothreonine305 def: "Protein MKL1_HUMAN with the residue 305 substituted with Phosphothreonine" [UniProtKB:Q969V6] xref: UniProtKB:Q969V6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058143 ! MKL1_HUMAN [Term] id: CCO:B0068213 name: MKL1_HUMAN-Phosphothreonine450 def: "Protein MKL1_HUMAN with the residue 450 substituted with Phosphothreonine" [UniProtKB:Q969V6] xref: UniProtKB:Q969V6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058143 ! MKL1_HUMAN [Term] id: CCO:B0068214 name: MKL1_HUMAN-Phosphoserine454 def: "Protein MKL1_HUMAN with the residue 454 substituted with Phosphoserine" [UniProtKB:Q969V6] xref: UniProtKB:Q969V6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058143 ! MKL1_HUMAN [Term] id: CCO:B0068215 name: MKL2_HUMAN-Phosphoserine66 def: "Protein MKL2_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q9ULH7] xref: UniProtKB:Q9ULH7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:B0068216 name: MKL2_HUMAN-Phosphothreonine367 def: "Protein MKL2_HUMAN with the residue 367 substituted with Phosphothreonine" [UniProtKB:Q9ULH7] xref: UniProtKB:Q9ULH7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:B0068217 name: MKL2_HUMAN-Phosphothreonine370 def: "Protein MKL2_HUMAN with the residue 370 substituted with Phosphothreonine" [UniProtKB:Q9ULH7] xref: UniProtKB:Q9ULH7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:B0068218 name: MKL2_HUMAN-Phosphoserine921 def: "Protein MKL2_HUMAN with the residue 921 substituted with Phosphoserine" [UniProtKB:Q9ULH7] xref: UniProtKB:Q9ULH7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:B0068219 name: MKNK1_HUMAN-Phosphothreonine250 def: "Protein MKNK1_HUMAN with the residue 250 substituted with Phosphothreonine" [UniProtKB:Q9BUB5] xref: UniProtKB:Q9BUB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:B0068220 name: MKNK1_HUMAN-Phosphothreonine255 def: "Protein MKNK1_HUMAN with the residue 255 substituted with Phosphothreonine" [UniProtKB:Q9BUB5] xref: UniProtKB:Q9BUB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:B0068221 name: MKNK1_HUMAN-Phosphothreonine385 def: "Protein MKNK1_HUMAN with the residue 385 substituted with Phosphothreonine" [UniProtKB:Q9BUB5] xref: UniProtKB:Q9BUB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:B0068222 name: MKNK1_HUMAN-Phosphoserine460 def: "Protein MKNK1_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q9BUB5] xref: UniProtKB:Q9BUB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:B0068223 name: MKNK2_HUMAN-Phosphothreonine244 def: "Protein MKNK2_HUMAN with the residue 244 substituted with Phosphothreonine" [UniProtKB:Q9HBH9] xref: UniProtKB:Q9HBH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058786 ! MKNK2_HUMAN [Term] id: CCO:B0068224 name: MKNK2_HUMAN-Phosphothreonine249 def: "Protein MKNK2_HUMAN with the residue 249 substituted with Phosphothreonine" [UniProtKB:Q9HBH9] xref: UniProtKB:Q9HBH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058786 ! MKNK2_HUMAN [Term] id: CCO:B0068225 name: MKNK2_HUMAN-Phosphothreonine379 def: "Protein MKNK2_HUMAN with the residue 379 substituted with Phosphothreonine" [UniProtKB:Q9HBH9] xref: UniProtKB:Q9HBH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058786 ! MKNK2_HUMAN [Term] id: CCO:B0068226 name: MLH1_HUMAN-Phosphoserine477 def: "Protein MLH1_HUMAN with the residue 477 substituted with Phosphoserine" [UniProtKB:P40692] xref: UniProtKB:P40692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_function CCO:F0004987 ! MutSalpha complex binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001601 ! MLH1_HUMAN [Term] id: CCO:B0068227 name: MLL4_HUMAN-Phosphothreonine172 def: "Protein MLL4_HUMAN with the residue 172 substituted with Phosphothreonine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068228 name: MLL4_HUMAN-Phosphothreonine176 def: "Protein MLL4_HUMAN with the residue 176 substituted with Phosphothreonine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068229 name: MLL4_HUMAN-Phosphoserine821 def: "Protein MLL4_HUMAN with the residue 821 substituted with Phosphoserine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068230 name: MLL4_HUMAN-Phosphoserine844 def: "Protein MLL4_HUMAN with the residue 844 substituted with Phosphoserine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068231 name: MLL4_HUMAN-Phosphoserine1032 def: "Protein MLL4_HUMAN with the residue 1032 substituted with Phosphoserine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068232 name: MLL4_HUMAN-Phosphoserine1035 def: "Protein MLL4_HUMAN with the residue 1035 substituted with Phosphoserine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068233 name: MLL4_HUMAN-Phosphoserine1930 def: "Protein MLL4_HUMAN with the residue 1930 substituted with Phosphoserine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068234 name: MLL4_HUMAN-Phosphothreonine1935 def: "Protein MLL4_HUMAN with the residue 1935 substituted with Phosphothreonine" [UniProtKB:Q9UMN6] xref: UniProtKB:Q9UMN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:B0068235 name: MLRV_HUMAN-N,N,N-trimethylalanine2 def: "Protein MLRV_HUMAN with the residue 2 substituted with N,N,N-trimethylalanine" [UniProtKB:P10916] comment: By similarity xref: UniProtKB:P10916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054982 ! MLRV_HUMAN [Term] id: CCO:B0068236 name: MLTK_HUMAN-Phosphothreonine628 def: "Protein MLTK_HUMAN with the residue 628 substituted with Phosphothreonine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0068237 name: MLTK_HUMAN-Phosphoserine727 def: "Protein MLTK_HUMAN with the residue 727 substituted with Phosphoserine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0068238 name: MLTK_HUMAN-Phosphoserine733 def: "Protein MLTK_HUMAN with the residue 733 substituted with Phosphoserine" [UniProtKB:Q9NYL2] xref: UniProtKB:Q9NYL2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:B0068239 name: MLXIP_HUMAN-Phosphoserine27 def: "Protein MLXIP_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q9HAP2] xref: UniProtKB:Q9HAP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000898 ! outer membrane relationship: transformation_of CCO:B0058765 ! MLXIP_HUMAN [Term] id: CCO:B0068240 name: MLXIP_HUMAN-Phosphoserine33 def: "Protein MLXIP_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:Q9HAP2] xref: UniProtKB:Q9HAP2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058765 ! MLXIP_HUMAN [Term] id: CCO:B0068241 name: MLX_HUMAN-Phosphoserine45 def: "Protein MLX_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q9UH92] comment: By similarity xref: UniProtKB:Q9UH92 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059130 ! MLX_HUMAN [Term] id: CCO:B0068242 name: MLX_HUMAN-Phosphoserine48 def: "Protein MLX_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q9UH92] comment: By similarity xref: UniProtKB:Q9UH92 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059130 ! MLX_HUMAN [Term] id: CCO:B0068243 name: MMS19_HUMAN-Phosphoserine371 def: "Protein MMS19_HUMAN with the residue 371 substituted with Phosphoserine" [UniProtKB:Q96T76] comment: By similarity xref: UniProtKB:Q96T76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000279 ! holo TFIIH complex relationship: transformation_of CCO:B0058403 ! MMS19_HUMAN [Term] id: CCO:B0068244 name: MMTA2_HUMAN-Phosphoserine127 def: "Protein MMTA2_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q9BU76] xref: UniProtKB:Q9BU76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062789 ! MMTA2_HUMAN [Term] id: CCO:B0068245 name: MMTA2_HUMAN-Phosphoserine164 def: "Protein MMTA2_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q9BU76] xref: UniProtKB:Q9BU76 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062789 ! MMTA2_HUMAN [Term] id: CCO:B0068246 name: MNX1_HUMAN-Phosphoserine77 def: "Protein MNX1_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P50219] xref: UniProtKB:P50219 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036823 ! MNX1_HUMAN [Term] id: CCO:B0068247 name: MNX1_HUMAN-Phosphoserine79 def: "Protein MNX1_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:P50219] xref: UniProtKB:P50219 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0036823 ! MNX1_HUMAN [Term] id: CCO:B0068248 name: MO4L2_HUMAN-Phosphoserine71 def: "Protein MO4L2_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q15014] xref: UniProtKB:Q15014 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0005370 ! MO4L2_HUMAN [Term] id: CCO:B0068249 name: MON1A_HUMAN-Phosphoserine31 def: "Protein MON1A_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q86VX9] xref: UniProtKB:Q86VX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005970 ! MON1A_HUMAN [Term] id: CCO:B0068250 name: MORN2_HUMAN-Phosphotyrosine38 def: "Protein MORN2_HUMAN with the residue 38 substituted with Phosphotyrosine" [UniProtKB:Q502X0] xref: UniProtKB:Q502X0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063520 ! MORN2_HUMAN [Term] id: CCO:B0068251 name: MP2K4_HUMAN-Phosphoserine90 def: "Protein MP2K4_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:P45985] xref: UniProtKB:P45985 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038116 ! MP2K4_HUMAN [Term] id: CCO:B0068252 name: MPDZ_HUMAN-Phosphoserine230 def: "Protein MPDZ_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:O75970] xref: UniProtKB:O75970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0063268 ! MPDZ_HUMAN [Term] id: CCO:B0068253 name: MPDZ_HUMAN-Phosphoserine483 def: "Protein MPDZ_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:O75970] xref: UniProtKB:O75970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063268 ! MPDZ_HUMAN [Term] id: CCO:B0068254 name: MPIP3_HUMAN-Phosphoserine38 def: "Protein MPIP3_HUMAN with the residue 38 substituted with Phosphoserine" [UniProtKB:P30307] xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0068255 name: MPIP3_HUMAN-Phosphothreonine48 def: "Protein MPIP3_HUMAN with the residue 48 substituted with Phosphothreonine" [UniProtKB:P30307] xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0068256 name: MPIP3_HUMAN-Phosphoserine57 def: "Protein MPIP3_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:P30307] xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0068257 name: MPIP3_HUMAN-Phosphoserine61 def: "Protein MPIP3_HUMAN with the residue 61 substituted with Phosphoserine" [UniProtKB:P30307] xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0068258 name: MPIP3_HUMAN-Phosphoserine64 def: "Protein MPIP3_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:P30307] xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0068259 name: MPIP3_HUMAN-Phosphothreonine67 def: "Protein MPIP3_HUMAN with the residue 67 substituted with Phosphothreonine" [UniProtKB:P30307] xref: UniProtKB:P30307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:B0068260 name: MPP2_HUMAN-Phosphoserine42 def: "Protein MPP2_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q14168] comment: By similarity xref: UniProtKB:Q14168 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000802 ! guanylate kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: transformation_of CCO:B0055968 ! MPP2_HUMAN [Term] id: CCO:B0068261 name: MPP8_HUMAN-Phosphoserine149 def: "Protein MPP8_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0068262 name: MPP8_HUMAN-Phosphoserine189 def: "Protein MPP8_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q99549] xref: UniProtKB:Q99549 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002072 ! MPP8_HUMAN [Term] id: CCO:B0068263 name: MPRI_HUMAN-Phosphoserine2409 def: "Protein MPRI_HUMAN with the residue 2409 substituted with Phosphoserine" [UniProtKB:P11717] xref: UniProtKB:P11717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054994 ! MPRI_HUMAN [Term] id: CCO:B0068264 name: MPRI_HUMAN-Phosphoserine2479 def: "Protein MPRI_HUMAN with the residue 2479 substituted with Phosphoserine" [UniProtKB:P11717] xref: UniProtKB:P11717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054994 ! MPRI_HUMAN [Term] id: CCO:B0068265 name: MPRI_HUMAN-Phosphoserine2484 def: "Protein MPRI_HUMAN with the residue 2484 substituted with Phosphoserine" [UniProtKB:P11717] xref: UniProtKB:P11717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054994 ! MPRI_HUMAN [Term] id: CCO:B0068266 name: MPZL1_HUMAN-Phosphoserine219 def: "Protein MPZL1_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:O95297] xref: UniProtKB:O95297 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054748 ! MPZL1_HUMAN [Term] id: CCO:B0068267 name: MPZL1_HUMAN-Phosphotyrosine241 def: "Protein MPZL1_HUMAN with the residue 241 substituted with Phosphotyrosine" [UniProtKB:O95297] xref: UniProtKB:O95297 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054748 ! MPZL1_HUMAN [Term] id: CCO:B0068268 name: MPZL1_HUMAN-Phosphotyrosine263 def: "Protein MPZL1_HUMAN with the residue 263 substituted with Phosphotyrosine" [UniProtKB:O95297] xref: UniProtKB:O95297 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054748 ! MPZL1_HUMAN [Term] id: CCO:B0068269 name: MRCKA_HUMAN-Phosphoserine222 def: "Protein MRCKA_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q5VT25] comment: by autocatalysis; xref: UniProtKB:Q5VT25 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:B0068270 name: MRCKA_HUMAN-Phosphoserine234 def: "Protein MRCKA_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q5VT25] comment: by autocatalysis; xref: UniProtKB:Q5VT25 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:B0068271 name: MRCKA_HUMAN-Phosphothreonine240 def: "Protein MRCKA_HUMAN with the residue 240 substituted with Phosphothreonine" [UniProtKB:Q5VT25] comment: by autocatalysis; xref: UniProtKB:Q5VT25 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:B0068272 name: MRCKA_HUMAN-Phosphoserine1545 def: "Protein MRCKA_HUMAN with the residue 1545 substituted with Phosphoserine" [UniProtKB:Q5VT25] xref: UniProtKB:Q5VT25 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:B0068273 name: MRCKA_HUMAN-Phosphoserine1719 def: "Protein MRCKA_HUMAN with the residue 1719 substituted with Phosphoserine" [UniProtKB:Q5VT25] xref: UniProtKB:Q5VT25 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:B0068274 name: MRCKA_HUMAN-Phosphoserine1721 def: "Protein MRCKA_HUMAN with the residue 1721 substituted with Phosphoserine" [UniProtKB:Q5VT25] xref: UniProtKB:Q5VT25 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:B0068275 name: MRCKB_HUMAN-Phosphoserine221 def: "Protein MRCKB_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q9Y5S2] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0001172 ! leading edge relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068276 name: MRCKB_HUMAN-Phosphoserine233 def: "Protein MRCKB_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:Q9Y5S2] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068277 name: MRCKB_HUMAN-Phosphothreonine239 def: "Protein MRCKB_HUMAN with the residue 239 substituted with Phosphothreonine" [UniProtKB:Q9Y5S2] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068278 name: MRCKB_HUMAN-Phosphoserine914 def: "Protein MRCKB_HUMAN with the residue 914 substituted with Phosphoserine" [UniProtKB:Q9Y5S2] xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068279 name: MRCKB_HUMAN-Phosphotyrosine954 def: "Protein MRCKB_HUMAN with the residue 954 substituted with Phosphotyrosine" [UniProtKB:Q9Y5S2] comment: By similarity xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068280 name: MRCKB_HUMAN-Phosphothreonine1196 def: "Protein MRCKB_HUMAN with the residue 1196 substituted with Phosphothreonine" [UniProtKB:Q9Y5S2] xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068281 name: MRCKB_HUMAN-Phosphoserine1690 def: "Protein MRCKB_HUMAN with the residue 1690 substituted with Phosphoserine" [UniProtKB:Q9Y5S2] xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068282 name: MRCKB_HUMAN-Phosphoserine1693 def: "Protein MRCKB_HUMAN with the residue 1693 substituted with Phosphoserine" [UniProtKB:Q9Y5S2] xref: UniProtKB:Q9Y5S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059385 ! MRCKB_HUMAN [Term] id: CCO:B0068283 name: MRCKG_HUMAN-Phosphoserine216 def: "Protein MRCKG_HUMAN with the residue 216 substituted with Phosphoserine" [UniProtKB:Q6DT37] comment: by autocatalysis; By similarity xref: UniProtKB:Q6DT37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056729 ! MRCKG_HUMAN [Term] id: CCO:B0068284 name: MRCKG_HUMAN-Phosphoserine228 def: "Protein MRCKG_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q6DT37] comment: by autocatalysis; By similarity xref: UniProtKB:Q6DT37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056729 ! MRCKG_HUMAN [Term] id: CCO:B0068285 name: MRCKG_HUMAN-Phosphothreonine234 def: "Protein MRCKG_HUMAN with the residue 234 substituted with Phosphothreonine" [UniProtKB:Q6DT37] comment: by autocatalysis; By similarity xref: UniProtKB:Q6DT37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056729 ! MRCKG_HUMAN [Term] id: CCO:B0068286 name: MRE11_HUMAN-Phosphoserine649 def: "Protein MRE11_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:P49959] xref: UniProtKB:P49959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000005 ! single-stranded DNA specific endodeoxyribonuclease activity relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0000917 ! endodeoxyribonuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:B0068287 name: MRGBP_HUMAN-Phosphoserine191 def: "Protein MRGBP_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q9NV56] xref: UniProtKB:Q9NV56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001724 ! H4/H2A histone acetyltransferase complex relationship: transformation_of CCO:B0005360 ! MRGBP_HUMAN [Term] id: CCO:B0068288 name: MRGBP_HUMAN-Phosphoserine195 def: "Protein MRGBP_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:Q9NV56] xref: UniProtKB:Q9NV56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005360 ! MRGBP_HUMAN [Term] id: CCO:B0068289 name: MRLC3_HUMAN-N-acetylserine2 def: "Protein MRLC3_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P19105] comment: By similarity xref: UniProtKB:P19105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:B0068290 name: MRLC3_HUMAN-Phosphothreonine18 def: "Protein MRLC3_HUMAN with the residue 18 substituted with Phosphothreonine" [UniProtKB:P19105] comment: by MLCK; xref: UniProtKB:P19105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000788 ! myosin complex relationship: transformation_of CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:B0068291 name: MRLC3_HUMAN-Phosphoserine19 def: "Protein MRLC3_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:P19105] xref: UniProtKB:P19105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:B0068292 name: MS3L1_HUMAN-Phosphoserine367 def: "Protein MS3L1_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q8N5Y2] xref: UniProtKB:Q8N5Y2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057482 ! MS3L1_HUMAN [Term] id: CCO:B0068293 name: MS3L1_HUMAN-Phosphoserine400 def: "Protein MS3L1_HUMAN with the residue 400 substituted with Phosphoserine" [UniProtKB:Q8N5Y2] xref: UniProtKB:Q8N5Y2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057482 ! MS3L1_HUMAN [Term] id: CCO:B0068294 name: MS3L1_HUMAN-Phosphoserine407 def: "Protein MS3L1_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q8N5Y2] xref: UniProtKB:Q8N5Y2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057482 ! MS3L1_HUMAN [Term] id: CCO:B0068295 name: MS3L1_HUMAN-Phosphoserine411 def: "Protein MS3L1_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q8N5Y2] xref: UniProtKB:Q8N5Y2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057482 ! MS3L1_HUMAN [Term] id: CCO:B0068296 name: MSH6_HUMAN-Phosphoserine79 def: "Protein MSH6_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0068297 name: MSH6_HUMAN-Phosphoserine91 def: "Protein MSH6_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0068298 name: MSH6_HUMAN-Phosphoserine200 def: "Protein MSH6_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:P52701] xref: UniProtKB:P52701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:B0068299 name: MST4_HUMAN-Phosphoserine300 def: "Protein MST4_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q9P289] xref: UniProtKB:Q9P289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:B0068300 name: MST4_HUMAN-Phosphoserine304 def: "Protein MST4_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q9P289] xref: UniProtKB:Q9P289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:B0068301 name: MST4_HUMAN-Phosphoserine306 def: "Protein MST4_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q9P289] xref: UniProtKB:Q9P289 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:B0068302 name: MT1H_HUMAN-N-acetylmethionine1 def: "Protein MT1H_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P80294] xref: UniProtKB:P80294 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063279 ! MT1H_HUMAN [Term] id: CCO:B0068303 name: MT2_HUMAN-N-acetylmethionine1 def: "Protein MT2_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P02795] xref: UniProtKB:P02795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054877 ! MT2_HUMAN [Term] id: CCO:B0068304 name: MT2_HUMAN-N6-acetyllysine51 def: "Protein MT2_HUMAN with the residue 51 substituted with N6-acetyllysine" [UniProtKB:P02795] xref: UniProtKB:P02795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054877 ! MT2_HUMAN [Term] id: CCO:B0068305 name: MT3_HUMAN-N-acetylmethionine1 def: "Protein MT3_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P25713] xref: UniProtKB:P25713 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055185 ! MT3_HUMAN [Term] id: CCO:B0068306 name: MTA1_HUMAN-Phosphoserine386 def: "Protein MTA1_HUMAN with the residue 386 substituted with Phosphoserine" [UniProtKB:Q13330] xref: UniProtKB:Q13330 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055899 ! MTA1_HUMAN [Term] id: CCO:B0068307 name: MTA1_HUMAN-Phosphoserine449 def: "Protein MTA1_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q13330] xref: UniProtKB:Q13330 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055899 ! MTA1_HUMAN [Term] id: CCO:B0068308 name: MTA1_HUMAN-Phosphothreonine467 def: "Protein MTA1_HUMAN with the residue 467 substituted with Phosphothreonine" [UniProtKB:Q13330] xref: UniProtKB:Q13330 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055899 ! MTA1_HUMAN [Term] id: CCO:B0068309 name: MTA1_HUMAN-Phosphoserine522 def: "Protein MTA1_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q13330] xref: UniProtKB:Q13330 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055899 ! MTA1_HUMAN [Term] id: CCO:B0068310 name: MTA1_HUMAN-Phosphothreonine564 def: "Protein MTA1_HUMAN with the residue 564 substituted with Phosphothreonine" [UniProtKB:Q13330] xref: UniProtKB:Q13330 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055899 ! MTA1_HUMAN [Term] id: CCO:B0068311 name: MTA1_HUMAN-Phosphoserine576 def: "Protein MTA1_HUMAN with the residue 576 substituted with Phosphoserine" [UniProtKB:Q13330] xref: UniProtKB:Q13330 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055899 ! MTA1_HUMAN [Term] id: CCO:B0068312 name: MTA2_HUMAN-Phosphoserine57 def: "Protein MTA2_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:O94776] xref: UniProtKB:O94776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000816 ! histone deacetylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000805 ! NuRD complex relationship: located_in CCO:C0000806 ! chromatin remodeling complex relationship: transformation_of CCO:B0054698 ! MTA2_HUMAN [Term] id: CCO:B0068313 name: MTA2_HUMAN-Phosphoserine435 def: "Protein MTA2_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:O94776] xref: UniProtKB:O94776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054698 ! MTA2_HUMAN [Term] id: CCO:B0068314 name: MTA2_HUMAN-Phosphothreonine540 def: "Protein MTA2_HUMAN with the residue 540 substituted with Phosphothreonine" [UniProtKB:O94776] xref: UniProtKB:O94776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054698 ! MTA2_HUMAN [Term] id: CCO:B0068315 name: MTBP_HUMAN-Phosphoserine639 def: "Protein MTBP_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:Q96DY7] xref: UniProtKB:Q96DY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041265 ! MTBP_HUMAN [Term] id: CCO:B0068316 name: MTCH1_HUMAN-Phosphoserine381 def: "Protein MTCH1_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9NZJ7] comment: By similarity xref: UniProtKB:Q9NZJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059001 ! MTCH1_HUMAN [Term] id: CCO:B0068317 name: MTG8R_HUMAN-Phosphoserine33 def: "Protein MTG8R_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:O43439] xref: UniProtKB:O43439 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054482 ! MTG8R_HUMAN [Term] id: CCO:B0068318 name: MTHFS_HUMAN-N-acetylalanine2 def: "Protein MTHFS_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P49914] comment: By similarity xref: UniProtKB:P49914 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062961 ! MTHFS_HUMAN [Term] id: CCO:B0068319 name: MTMR6_HUMAN-Phosphoserine589 def: "Protein MTMR6_HUMAN with the residue 589 substituted with Phosphoserine" [UniProtKB:Q9Y217] xref: UniProtKB:Q9Y217 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006052 ! MTMR6_HUMAN [Term] id: CCO:B0068320 name: MTMR9_HUMAN-Phosphoserine548 def: "Protein MTMR9_HUMAN with the residue 548 substituted with Phosphoserine" [UniProtKB:Q96QG7] xref: UniProtKB:Q96QG7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004354 ! enzyme regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026696 ! MTMR9_HUMAN [Term] id: CCO:B0068321 name: MTPN_HUMAN-N-acetylcysteine2 def: "Protein MTPN_HUMAN with the residue 2 substituted with N-acetylcysteine" [UniProtKB:P58546] comment: By similarity xref: UniProtKB:P58546 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001004 ! axon relationship: transformation_of CCO:B0055571 ! MTPN_HUMAN [Term] id: CCO:B0068322 name: MTSSL_HUMAN-Phosphoserine441 def: "Protein MTSSL_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0068323 name: MTSSL_HUMAN-Phosphoserine456 def: "Protein MTSSL_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0068324 name: MTSSL_HUMAN-Phosphoserine579 def: "Protein MTSSL_HUMAN with the residue 579 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0068325 name: MTSSL_HUMAN-Phosphoserine624 def: "Protein MTSSL_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0068326 name: MTSSL_HUMAN-Phosphoserine634 def: "Protein MTSSL_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:Q765P7] xref: UniProtKB:Q765P7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039174 ! MTSSL_HUMAN [Term] id: CCO:B0068327 name: MX1_HUMAN-Phosphotyrosine129 def: "Protein MX1_HUMAN with the residue 129 substituted with Phosphotyrosine" [UniProtKB:P20591] xref: UniProtKB:P20591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055123 ! MX1_HUMAN [Term] id: CCO:B0068328 name: MX1_HUMAN-Phosphotyrosine451 def: "Protein MX1_HUMAN with the residue 451 substituted with Phosphotyrosine" [UniProtKB:P20591] xref: UniProtKB:P20591 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055123 ! MX1_HUMAN [Term] id: CCO:B0068329 name: MY18A_HUMAN-Phosphoserine72 def: "Protein MY18A_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:Q92614] comment: By similarity xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068330 name: MY18A_HUMAN-Phosphoserine74 def: "Protein MY18A_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q92614] comment: By similarity xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068331 name: MY18A_HUMAN-Phosphoserine83 def: "Protein MY18A_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q92614] comment: By similarity xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068332 name: MY18A_HUMAN-Phosphoserine102 def: "Protein MY18A_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q92614] comment: By similarity xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068333 name: MY18A_HUMAN-Phosphoserine140 def: "Protein MY18A_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068334 name: MY18A_HUMAN-Phosphoserine164 def: "Protein MY18A_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q92614] comment: By similarity xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068335 name: MY18A_HUMAN-Phosphoserine234 def: "Protein MY18A_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068336 name: MY18A_HUMAN-Phosphoserine1039 def: "Protein MY18A_HUMAN with the residue 1039 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068337 name: MY18A_HUMAN-Phosphoserine1063 def: "Protein MY18A_HUMAN with the residue 1063 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068338 name: MY18A_HUMAN-Phosphoserine1067 def: "Protein MY18A_HUMAN with the residue 1067 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068339 name: MY18A_HUMAN-Phosphoserine1070 def: "Protein MY18A_HUMAN with the residue 1070 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068340 name: MY18A_HUMAN-Phosphoserine1942 def: "Protein MY18A_HUMAN with the residue 1942 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068341 name: MY18A_HUMAN-Phosphoserine1970 def: "Protein MY18A_HUMAN with the residue 1970 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068342 name: MY18A_HUMAN-Phosphoserine1974 def: "Protein MY18A_HUMAN with the residue 1974 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068343 name: MY18A_HUMAN-Phosphoserine1998 def: "Protein MY18A_HUMAN with the residue 1998 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068344 name: MY18A_HUMAN-Phosphoserine2002 def: "Protein MY18A_HUMAN with the residue 2002 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068345 name: MY18A_HUMAN-Phosphoserine2007 def: "Protein MY18A_HUMAN with the residue 2007 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068346 name: MY18A_HUMAN-Phosphoserine2020 def: "Protein MY18A_HUMAN with the residue 2020 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000788 ! myosin complex relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068347 name: MY18A_HUMAN-Phosphoserine2036 def: "Protein MY18A_HUMAN with the residue 2036 substituted with Phosphoserine" [UniProtKB:Q92614] comment: By similarity xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068348 name: MY18A_HUMAN-Phosphoserine2041 def: "Protein MY18A_HUMAN with the residue 2041 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068349 name: MY18A_HUMAN-Phosphoserine2043 def: "Protein MY18A_HUMAN with the residue 2043 substituted with Phosphoserine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068350 name: MY18A_HUMAN-Phosphothreonine2045 def: "Protein MY18A_HUMAN with the residue 2045 substituted with Phosphothreonine" [UniProtKB:Q92614] xref: UniProtKB:Q92614 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:B0068351 name: MYCB2_HUMAN-Phosphoserine1586 def: "Protein MYCB2_HUMAN with the residue 1586 substituted with Phosphoserine" [UniProtKB:O75592] comment: By similarity xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068352 name: MYCB2_HUMAN-Phosphoserine2749 def: "Protein MYCB2_HUMAN with the residue 2749 substituted with Phosphoserine" [UniProtKB:O75592] xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068353 name: MYCB2_HUMAN-Phosphoserine2751 def: "Protein MYCB2_HUMAN with the residue 2751 substituted with Phosphoserine" [UniProtKB:O75592] xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068354 name: MYCB2_HUMAN-Phosphoserine2774 def: "Protein MYCB2_HUMAN with the residue 2774 substituted with Phosphoserine" [UniProtKB:O75592] xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068355 name: MYCB2_HUMAN-Phosphoserine2831 def: "Protein MYCB2_HUMAN with the residue 2831 substituted with Phosphoserine" [UniProtKB:O75592] xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068356 name: MYCB2_HUMAN-Phosphoserine3052 def: "Protein MYCB2_HUMAN with the residue 3052 substituted with Phosphoserine" [UniProtKB:O75592] xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068357 name: MYCB2_HUMAN-Phosphothreonine3883 def: "Protein MYCB2_HUMAN with the residue 3883 substituted with Phosphothreonine" [UniProtKB:O75592] comment: By similarity xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068358 name: MYCB2_HUMAN-Phosphoserine3893 def: "Protein MYCB2_HUMAN with the residue 3893 substituted with Phosphoserine" [UniProtKB:O75592] xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068359 name: MYCB2_HUMAN-Phosphoserine3894 def: "Protein MYCB2_HUMAN with the residue 3894 substituted with Phosphoserine" [UniProtKB:O75592] xref: UniProtKB:O75592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054654 ! MYCB2_HUMAN [Term] id: CCO:B0068360 name: MYCL1_HUMAN-Phosphothreonine310 def: "Protein MYCL1_HUMAN with the residue 310 substituted with Phosphothreonine" [UniProtKB:P12524] comment: By similarity xref: UniProtKB:P12524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055000 ! MYCL1_HUMAN [Term] id: CCO:B0068361 name: MYCL1_HUMAN-Phosphoserine313 def: "Protein MYCL1_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:P12524] comment: By similarity xref: UniProtKB:P12524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055000 ! MYCL1_HUMAN [Term] id: CCO:B0068362 name: MYCL2_HUMAN-Phosphoserine306 def: "Protein MYCL2_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:P12525] comment: By similarity xref: UniProtKB:P12525 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055001 ! MYCL2_HUMAN [Term] id: CCO:B0068363 name: MYCN_HUMAN-Phosphothreonine58 def: "Protein MYCN_HUMAN with the residue 58 substituted with Phosphothreonine" [UniProtKB:P04198] xref: UniProtKB:P04198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:B0068364 name: MYCN_HUMAN-Phosphoserine62 def: "Protein MYCN_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:P04198] xref: UniProtKB:P04198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:B0068365 name: MYCN_HUMAN-Phosphoserine261 def: "Protein MYCN_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:P04198] comment: by CK2; xref: UniProtKB:P04198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:B0068366 name: MYCN_HUMAN-Phosphoserine263 def: "Protein MYCN_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:P04198] comment: by CK2; xref: UniProtKB:P04198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:B0068367 name: MYCPP_HUMAN-Phosphoserine728 def: "Protein MYCPP_HUMAN with the residue 728 substituted with Phosphoserine" [UniProtKB:Q7Z401] xref: UniProtKB:Q7Z401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057157 ! MYCPP_HUMAN [Term] id: CCO:B0068368 name: MYCPP_HUMAN-Phosphoserine731 def: "Protein MYCPP_HUMAN with the residue 731 substituted with Phosphoserine" [UniProtKB:Q7Z401] xref: UniProtKB:Q7Z401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057157 ! MYCPP_HUMAN [Term] id: CCO:B0068369 name: MYCPP_HUMAN-Phosphoserine1281 def: "Protein MYCPP_HUMAN with the residue 1281 substituted with Phosphoserine" [UniProtKB:Q7Z401] xref: UniProtKB:Q7Z401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057157 ! MYCPP_HUMAN [Term] id: CCO:B0068370 name: MYCPP_HUMAN-Phosphoserine1511 def: "Protein MYCPP_HUMAN with the residue 1511 substituted with Phosphoserine" [UniProtKB:Q7Z401] xref: UniProtKB:Q7Z401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057157 ! MYCPP_HUMAN [Term] id: CCO:B0068371 name: MYCPP_HUMAN-Phosphoserine1587 def: "Protein MYCPP_HUMAN with the residue 1587 substituted with Phosphoserine" [UniProtKB:Q7Z401] xref: UniProtKB:Q7Z401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057157 ! MYCPP_HUMAN [Term] id: CCO:B0068372 name: MYH10_HUMAN-Phosphotyrosine1415 def: "Protein MYH10_HUMAN with the residue 1415 substituted with Phosphotyrosine" [UniProtKB:P35580] xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0068373 name: MYH10_HUMAN-Phosphoserine1939 def: "Protein MYH10_HUMAN with the residue 1939 substituted with Phosphoserine" [UniProtKB:P35580] xref: UniProtKB:P35580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:B0068374 name: MYH14_HUMAN-Phosphotyrosine778 def: "Protein MYH14_HUMAN with the residue 778 substituted with Phosphotyrosine" [UniProtKB:Q7Z406] xref: UniProtKB:Q7Z406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005971 ! MYH14_HUMAN [Term] id: CCO:B0068375 name: MYH9_HUMAN-Phosphotyrosine1408 def: "Protein MYH9_HUMAN with the residue 1408 substituted with Phosphotyrosine" [UniProtKB:P35579] xref: UniProtKB:P35579 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:B0068376 name: MYL6_HUMAN-Phosphotyrosine29 def: "Protein MYL6_HUMAN with the residue 29 substituted with Phosphotyrosine" [UniProtKB:P60660] xref: UniProtKB:P60660 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_function CCO:F0004599 ! actin-dependent ATPase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000788 ! myosin complex relationship: located_in CCO:C0000790 ! unconventional myosin complex relationship: transformation_of CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:B0068377 name: MYL9_HUMAN-N-acetylserine2 def: "Protein MYL9_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P24844] comment: By similarity xref: UniProtKB:P24844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063421 ! MYL9_HUMAN [Term] id: CCO:B0068378 name: MYL9_HUMAN-Phosphothreonine19 def: "Protein MYL9_HUMAN with the residue 19 substituted with Phosphothreonine" [UniProtKB:P24844] comment: by MLCK; xref: UniProtKB:P24844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063421 ! MYL9_HUMAN [Term] id: CCO:B0068379 name: MYL9_HUMAN-Phosphoserine20 def: "Protein MYL9_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P24844] comment: by MLCK; xref: UniProtKB:P24844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063421 ! MYL9_HUMAN [Term] id: CCO:B0068380 name: MYL9_HUMAN-Phosphoserine29 def: "Protein MYL9_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:P24844] comment: By similarity xref: UniProtKB:P24844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000423 ! muscle myosin complex relationship: located_in CCO:C0000788 ! myosin complex relationship: transformation_of CCO:B0063421 ! MYL9_HUMAN [Term] id: CCO:B0068381 name: MYL9_HUMAN-Phosphothreonine135 def: "Protein MYL9_HUMAN with the residue 135 substituted with Phosphothreonine" [UniProtKB:P24844] comment: By similarity xref: UniProtKB:P24844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063421 ! MYL9_HUMAN [Term] id: CCO:B0068382 name: MYLK_HUMAN-Phosphoserine1438 def: "Protein MYLK_HUMAN with the residue 1438 substituted with Phosphoserine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0068383 name: MYLK_HUMAN-Phosphoserine1760 def: "Protein MYLK_HUMAN with the residue 1760 substituted with Phosphoserine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0068384 name: MYLK_HUMAN-Phosphoserine1772 def: "Protein MYLK_HUMAN with the residue 1772 substituted with Phosphoserine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001055 ! myosin light chain kinase activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0068385 name: MYLK_HUMAN-Phosphothreonine1774 def: "Protein MYLK_HUMAN with the residue 1774 substituted with Phosphothreonine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0068386 name: MYLK_HUMAN-Phosphothreonine1778 def: "Protein MYLK_HUMAN with the residue 1778 substituted with Phosphothreonine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0068387 name: MYLK_HUMAN-Phosphoserine1779 def: "Protein MYLK_HUMAN with the residue 1779 substituted with Phosphoserine" [UniProtKB:Q15746] xref: UniProtKB:Q15746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0036528 ! MYLK_HUMAN [Term] id: CCO:B0068388 name: MYO10_HUMAN-Phosphoserine960 def: "Protein MYO10_HUMAN with the residue 960 substituted with Phosphoserine" [UniProtKB:Q9HD67] xref: UniProtKB:Q9HD67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058826 ! MYO10_HUMAN [Term] id: CCO:B0068389 name: MYO10_HUMAN-Phosphoserine962 def: "Protein MYO10_HUMAN with the residue 962 substituted with Phosphoserine" [UniProtKB:Q9HD67] xref: UniProtKB:Q9HD67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058826 ! MYO10_HUMAN [Term] id: CCO:B0068390 name: MYO10_HUMAN-Phosphoserine968 def: "Protein MYO10_HUMAN with the residue 968 substituted with Phosphoserine" [UniProtKB:Q9HD67] xref: UniProtKB:Q9HD67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000321 ! motor activity relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000788 ! myosin complex relationship: transformation_of CCO:B0058826 ! MYO10_HUMAN [Term] id: CCO:B0068391 name: MYO10_HUMAN-Phosphoserine969 def: "Protein MYO10_HUMAN with the residue 969 substituted with Phosphoserine" [UniProtKB:Q9HD67] xref: UniProtKB:Q9HD67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058826 ! MYO10_HUMAN [Term] id: CCO:B0068392 name: MYO10_HUMAN-Phosphoserine1007 def: "Protein MYO10_HUMAN with the residue 1007 substituted with Phosphoserine" [UniProtKB:Q9HD67] xref: UniProtKB:Q9HD67 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058826 ! MYO10_HUMAN [Term] id: CCO:B0068393 name: MYO1C_HUMAN-N-acetylmethionine1 def: "Protein MYO1C_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:O00159] xref: UniProtKB:O00159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063063 ! MYO1C_HUMAN [Term] id: CCO:B0068394 name: MYO1C_HUMAN-Phosphoserine3 def: "Protein MYO1C_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:O00159] xref: UniProtKB:O00159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063063 ! MYO1C_HUMAN [Term] id: CCO:B0068395 name: MYO1C_HUMAN-N6-methyllysine348 def: "Protein MYO1C_HUMAN with the residue 348 substituted with N6-methyllysine" [UniProtKB:O00159] xref: UniProtKB:O00159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063063 ! MYO1C_HUMAN [Term] id: CCO:B0068396 name: MYO1C_HUMAN-Phosphoserine373 def: "Protein MYO1C_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:O00159] xref: UniProtKB:O00159 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063063 ! MYO1C_HUMAN [Term] id: CCO:B0068397 name: MYO1D_HUMAN-Phosphotyrosine536 def: "Protein MYO1D_HUMAN with the residue 536 substituted with Phosphotyrosine" [UniProtKB:O94832] comment: By similarity xref: UniProtKB:O94832 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063055 ! MYO1D_HUMAN [Term] id: CCO:B0068398 name: MYO9B_HUMAN-Phosphoserine716 def: "Protein MYO9B_HUMAN with the residue 716 substituted with Phosphoserine" [UniProtKB:Q13459] xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0068399 name: MYO9B_HUMAN-Phosphoserine1354 def: "Protein MYO9B_HUMAN with the residue 1354 substituted with Phosphoserine" [UniProtKB:Q13459] xref: UniProtKB:Q13459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031122 ! MYO9B_HUMAN [Term] id: CCO:B0068400 name: MYPC3_HUMAN-Phosphoserine275 def: "Protein MYPC3_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q14896] comment: by PKA and PKC; By similarity xref: UniProtKB:Q14896 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056023 ! MYPC3_HUMAN [Term] id: CCO:B0068401 name: MYPC3_HUMAN-Phosphoserine284 def: "Protein MYPC3_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q14896] comment: by PKA and PKC; By similarity xref: UniProtKB:Q14896 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056023 ! MYPC3_HUMAN [Term] id: CCO:B0068402 name: MYPC3_HUMAN-Phosphoserine304 def: "Protein MYPC3_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q14896] comment: by PKA and PKC; By similarity xref: UniProtKB:Q14896 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056023 ! MYPC3_HUMAN [Term] id: CCO:B0068403 name: MYPT1_HUMAN-Phosphoserine422 def: "Protein MYPT1_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:O14974] xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068404 name: MYPT1_HUMAN-Phosphothreonine443 def: "Protein MYPT1_HUMAN with the residue 443 substituted with Phosphothreonine" [UniProtKB:O14974] comment: By similarity xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068405 name: MYPT1_HUMAN-Phosphoserine445 def: "Protein MYPT1_HUMAN with the residue 445 substituted with Phosphoserine" [UniProtKB:O14974] xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068406 name: MYPT1_HUMAN-Phosphoserine507 def: "Protein MYPT1_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:O14974] xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068407 name: MYPT1_HUMAN-Phosphothreonine508 def: "Protein MYPT1_HUMAN with the residue 508 substituted with Phosphothreonine" [UniProtKB:O14974] comment: By similarity xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068408 name: MYPT1_HUMAN-Phosphoserine509 def: "Protein MYPT1_HUMAN with the residue 509 substituted with Phosphoserine" [UniProtKB:O14974] comment: By similarity xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068409 name: MYPT1_HUMAN-Phosphoserine566 def: "Protein MYPT1_HUMAN with the residue 566 substituted with Phosphoserine" [UniProtKB:O14974] comment: By similarity xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068410 name: MYPT1_HUMAN-Phosphoserine569 def: "Protein MYPT1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:O14974] comment: By similarity xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068411 name: MYPT1_HUMAN-Phosphothreonine696 def: "Protein MYPT1_HUMAN with the residue 696 substituted with Phosphothreonine" [UniProtKB:O14974] comment: by ROCK1 and CDC42BP; xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068412 name: MYPT1_HUMAN-Phosphoserine852 def: "Protein MYPT1_HUMAN with the residue 852 substituted with Phosphoserine" [UniProtKB:O14974] comment: by ROCK1; By similarity xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068413 name: MYPT1_HUMAN-Phosphoserine871 def: "Protein MYPT1_HUMAN with the residue 871 substituted with Phosphoserine" [UniProtKB:O14974] comment: By similarity xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068414 name: MYPT1_HUMAN-Phosphotyrosine890 def: "Protein MYPT1_HUMAN with the residue 890 substituted with Phosphotyrosine" [UniProtKB:O14974] xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068415 name: MYPT1_HUMAN-Phosphotyrosine901 def: "Protein MYPT1_HUMAN with the residue 901 substituted with Phosphotyrosine" [UniProtKB:O14974] xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068416 name: MYPT1_HUMAN-Phosphoserine910 def: "Protein MYPT1_HUMAN with the residue 910 substituted with Phosphoserine" [UniProtKB:O14974] xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068417 name: MYPT1_HUMAN-Phosphotyrosine911 def: "Protein MYPT1_HUMAN with the residue 911 substituted with Phosphotyrosine" [UniProtKB:O14974] xref: UniProtKB:O14974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:B0068418 name: MYPT2_HUMAN-Phosphoserine839 def: "Protein MYPT2_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:O60237] comment: By similarity xref: UniProtKB:O60237 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054535 ! MYPT2_HUMAN [Term] id: CCO:B0068419 name: MYPT2_HUMAN-Phosphoserine947 def: "Protein MYPT2_HUMAN with the residue 947 substituted with Phosphoserine" [UniProtKB:O60237] xref: UniProtKB:O60237 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054535 ! MYPT2_HUMAN [Term] id: CCO:B0068420 name: MYSM1_HUMAN-Phosphoserine218 def: "Protein MYSM1_HUMAN with the residue 218 substituted with Phosphoserine" [UniProtKB:Q5VVJ2] xref: UniProtKB:Q5VVJ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056659 ! MYSM1_HUMAN [Term] id: CCO:B0068421 name: MYSM1_HUMAN-Phosphoserine234 def: "Protein MYSM1_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q5VVJ2] xref: UniProtKB:Q5VVJ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056659 ! MYSM1_HUMAN [Term] id: CCO:B0068422 name: MYSM1_HUMAN-Phosphoserine267 def: "Protein MYSM1_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q5VVJ2] xref: UniProtKB:Q5VVJ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056659 ! MYSM1_HUMAN [Term] id: CCO:B0068423 name: MYST1_HUMAN-Phosphoserine37 def: "Protein MYST1_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q9H7Z6] comment: By similarity xref: UniProtKB:Q9H7Z6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058748 ! MYST1_HUMAN [Term] id: CCO:B0068424 name: MYST1_HUMAN-Phosphoserine42 def: "Protein MYST1_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q9H7Z6] comment: By similarity xref: UniProtKB:Q9H7Z6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000103 ! kinetochore relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058748 ! MYST1_HUMAN [Term] id: CCO:B0068425 name: MYST3_HUMAN-Phosphothreonine418 def: "Protein MYST3_HUMAN with the residue 418 substituted with Phosphothreonine" [UniProtKB:Q92794] xref: UniProtKB:Q92794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:B0068426 name: MYST3_HUMAN-Phosphoserine420 def: "Protein MYST3_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:Q92794] xref: UniProtKB:Q92794 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:B0068427 name: MZF1_HUMAN-Phosphoserine394 def: "Protein MZF1_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:P28698] xref: UniProtKB:P28698 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055206 ! MZF1_HUMAN [Term] id: CCO:B0068428 name: NAB1_HUMAN-Phosphoserine328 def: "Protein NAB1_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q13506] xref: UniProtKB:Q13506 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055920 ! NAB1_HUMAN [Term] id: CCO:B0068429 name: NAB1_HUMAN-Phosphoserine403 def: "Protein NAB1_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:Q13506] comment: By similarity xref: UniProtKB:Q13506 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055920 ! NAB1_HUMAN [Term] id: CCO:B0068430 name: NAB2_HUMAN-Phosphoserine6 def: "Protein NAB2_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q15742] xref: UniProtKB:Q15742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056102 ! NAB2_HUMAN [Term] id: CCO:B0068431 name: NAB2_HUMAN-Phosphoserine159 def: "Protein NAB2_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:Q15742] xref: UniProtKB:Q15742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056102 ! NAB2_HUMAN [Term] id: CCO:B0068432 name: NAB2_HUMAN-Phosphoserine162 def: "Protein NAB2_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:Q15742] xref: UniProtKB:Q15742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056102 ! NAB2_HUMAN [Term] id: CCO:B0068433 name: NAB2_HUMAN-Phosphoserine171 def: "Protein NAB2_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q15742] xref: UniProtKB:Q15742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056102 ! NAB2_HUMAN [Term] id: CCO:B0068434 name: NAB2_HUMAN-Phosphoserine479 def: "Protein NAB2_HUMAN with the residue 479 substituted with Phosphoserine" [UniProtKB:Q15742] xref: UniProtKB:Q15742 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056102 ! NAB2_HUMAN [Term] id: CCO:B0068435 name: NACA_HUMAN-Phosphoserine191 def: "Protein NACA_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q13765] xref: UniProtKB:Q13765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:B0068436 name: NAGK_HUMAN-Phosphoserine76 def: "Protein NAGK_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q9UJ70] xref: UniProtKB:Q9UJ70 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062854 ! NAGK_HUMAN [Term] id: CCO:B0068437 name: NAGK_HUMAN-Phosphotyrosine205 def: "Protein NAGK_HUMAN with the residue 205 substituted with Phosphotyrosine" [UniProtKB:Q9UJ70] xref: UniProtKB:Q9UJ70 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002386 ! N-acylmannosamine kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006073 ! N-acetylglucosamine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0062854 ! NAGK_HUMAN [Term] id: CCO:B0068438 name: NAMPT_HUMAN-Phosphotyrosine34 def: "Protein NAMPT_HUMAN with the residue 34 substituted with Phosphotyrosine" [UniProtKB:P43490] xref: UniProtKB:P43490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0006591 ! nicotinamide phosphoribosyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055366 ! NAMPT_HUMAN [Term] id: CCO:B0068439 name: NAMPT_HUMAN-Phosphotyrosine188 def: "Protein NAMPT_HUMAN with the residue 188 substituted with Phosphotyrosine" [UniProtKB:P43490] xref: UniProtKB:P43490 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055366 ! NAMPT_HUMAN [Term] id: CCO:B0068440 name: NARG1_HUMAN-Phosphoserine855 def: "Protein NARG1_HUMAN with the residue 855 substituted with Phosphoserine" [UniProtKB:Q9BXJ9] xref: UniProtKB:Q9BXJ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003130 ! acetyltransferase activity relationship: has_function CCO:F0005784 ! ribosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058556 ! NARG1_HUMAN [Term] id: CCO:B0068441 name: NARG1_HUMAN-Phosphoserine856 def: "Protein NARG1_HUMAN with the residue 856 substituted with Phosphoserine" [UniProtKB:Q9BXJ9] xref: UniProtKB:Q9BXJ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058556 ! NARG1_HUMAN [Term] id: CCO:B0068442 name: NASP_HUMAN-Phosphoserine408 def: "Protein NASP_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0068443 name: NASP_HUMAN-Phosphothreonine683 def: "Protein NASP_HUMAN with the residue 683 substituted with Phosphothreonine" [UniProtKB:P49321] xref: UniProtKB:P49321 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001626 ! NASP_HUMAN [Term] id: CCO:B0068444 name: NAT10_HUMAN-Phosphoserine934 def: "Protein NAT10_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:Q9H0A0] xref: UniProtKB:Q9H0A0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038667 ! NAT10_HUMAN [Term] id: CCO:B0068445 name: NAT10_HUMAN-Phosphoserine984 def: "Protein NAT10_HUMAN with the residue 984 substituted with Phosphoserine" [UniProtKB:Q9H0A0] xref: UniProtKB:Q9H0A0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0038667 ! NAT10_HUMAN [Term] id: CCO:B0068446 name: NAT10_HUMAN-Phosphoserine987 def: "Protein NAT10_HUMAN with the residue 987 substituted with Phosphoserine" [UniProtKB:Q9H0A0] xref: UniProtKB:Q9H0A0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001700 ! N-acetyltransferase activity relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0038667 ! NAT10_HUMAN [Term] id: CCO:B0068447 name: NBEA_HUMAN-Phosphoserine1529 def: "Protein NBEA_HUMAN with the residue 1529 substituted with Phosphoserine" [UniProtKB:Q8NFP9] comment: By similarity xref: UniProtKB:Q8NFP9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000381 ! trans-Golgi network relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063490 ! NBEA_HUMAN [Term] id: CCO:B0068448 name: NC2B_HUMAN-Phosphoserine105 def: "Protein NC2B_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q01658] xref: UniProtKB:Q01658 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055692 ! NC2B_HUMAN [Term] id: CCO:B0068449 name: NC2B_HUMAN-Phosphoserine166 def: "Protein NC2B_HUMAN with the residue 166 substituted with Phosphoserine" [UniProtKB:Q01658] xref: UniProtKB:Q01658 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055692 ! NC2B_HUMAN [Term] id: CCO:B0068450 name: NC2B_HUMAN-Phosphoserine167 def: "Protein NC2B_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:Q01658] xref: UniProtKB:Q01658 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055692 ! NC2B_HUMAN [Term] id: CCO:B0068451 name: NCBP1_HUMAN-Phosphothreonine21 def: "Protein NCBP1_HUMAN with the residue 21 substituted with Phosphothreonine" [UniProtKB:Q09161] xref: UniProtKB:Q09161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055805 ! NCBP1_HUMAN [Term] id: CCO:B0068452 name: NCBP1_HUMAN-Phosphoserine22 def: "Protein NCBP1_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:Q09161] xref: UniProtKB:Q09161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000071 ! RNA cap binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0002172 ! mRNA cap binding complex relationship: transformation_of CCO:B0055805 ! NCBP1_HUMAN [Term] id: CCO:B0068453 name: NCBP1_HUMAN-Phosphoserine674 def: "Protein NCBP1_HUMAN with the residue 674 substituted with Phosphoserine" [UniProtKB:Q09161] xref: UniProtKB:Q09161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055805 ! NCBP1_HUMAN [Term] id: CCO:B0068454 name: NCBP2_HUMAN-Phosphoserine13 def: "Protein NCBP2_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P52298] comment: By similarity xref: UniProtKB:P52298 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:B0068455 name: NCBP2_HUMAN-Phosphoserine18 def: "Protein NCBP2_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:P52298] xref: UniProtKB:P52298 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:B0068456 name: NCF1_HUMAN-Phosphoserine303 def: "Protein NCF1_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:P14598] xref: UniProtKB:P14598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:B0068457 name: NCF1_HUMAN-Phosphoserine304 def: "Protein NCF1_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:P14598] xref: UniProtKB:P14598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:B0068458 name: NCF1_HUMAN-Phosphoserine320 def: "Protein NCF1_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:P14598] xref: UniProtKB:P14598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:B0068459 name: NCF1_HUMAN-Phosphoserine328 def: "Protein NCF1_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P14598] xref: UniProtKB:P14598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:B0068460 name: NCF1_HUMAN-Phosphoserine345 def: "Protein NCF1_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:P14598] xref: UniProtKB:P14598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:B0068461 name: NCF1_HUMAN-Phosphoserine348 def: "Protein NCF1_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:P14598] xref: UniProtKB:P14598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:B0068462 name: NCK1_HUMAN-Phosphoserine85 def: "Protein NCK1_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:P16333] xref: UniProtKB:P16333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055048 ! NCK1_HUMAN [Term] id: CCO:B0068463 name: NCK1_HUMAN-Phosphoserine96 def: "Protein NCK1_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:P16333] xref: UniProtKB:P16333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000734 ! vesicle membrane relationship: transformation_of CCO:B0055048 ! NCK1_HUMAN [Term] id: CCO:B0068464 name: NCK1_HUMAN-Phosphotyrosine105 def: "Protein NCK1_HUMAN with the residue 105 substituted with Phosphotyrosine" [UniProtKB:P16333] xref: UniProtKB:P16333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055048 ! NCK1_HUMAN [Term] id: CCO:B0068465 name: NCK2_HUMAN-Phosphothreonine92 def: "Protein NCK2_HUMAN with the residue 92 substituted with Phosphothreonine" [UniProtKB:O43639] xref: UniProtKB:O43639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_function CCO:F0004332 ! receptor signaling complex scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: transformation_of CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:B0068466 name: NCK2_HUMAN-Phosphotyrosine110 def: "Protein NCK2_HUMAN with the residue 110 substituted with Phosphotyrosine" [UniProtKB:O43639] xref: UniProtKB:O43639 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:B0068467 name: NCOA1_HUMAN-Phosphoserine103 def: "Protein NCOA1_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068468 name: NCOA1_HUMAN-Phosphoserine372 def: "Protein NCOA1_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001882 ! acyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005585 ! nuclear hormone receptor binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068469 name: NCOA1_HUMAN-Phosphoserine395 def: "Protein NCOA1_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068470 name: NCOA1_HUMAN-Phosphoserine517 def: "Protein NCOA1_HUMAN with the residue 517 substituted with Phosphoserine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068471 name: NCOA1_HUMAN-Phosphoserine569 def: "Protein NCOA1_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068472 name: NCOA1_HUMAN-Phosphoserine1033 def: "Protein NCOA1_HUMAN with the residue 1033 substituted with Phosphoserine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068473 name: NCOA1_HUMAN-Phosphothreonine1179 def: "Protein NCOA1_HUMAN with the residue 1179 substituted with Phosphothreonine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068474 name: NCOA1_HUMAN-Phosphoserine1185 def: "Protein NCOA1_HUMAN with the residue 1185 substituted with Phosphoserine" [UniProtKB:Q15788] xref: UniProtKB:Q15788 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056112 ! NCOA1_HUMAN [Term] id: CCO:B0068475 name: NCOA2_HUMAN-Phosphoserine493 def: "Protein NCOA2_HUMAN with the residue 493 substituted with Phosphoserine" [UniProtKB:Q15596] xref: UniProtKB:Q15596 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056076 ! NCOA2_HUMAN [Term] id: CCO:B0068476 name: NCOA2_HUMAN-Phosphoserine699 def: "Protein NCOA2_HUMAN with the residue 699 substituted with Phosphoserine" [UniProtKB:Q15596] comment: By similarity xref: UniProtKB:Q15596 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004420 ! thyroid hormone receptor coactivator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005585 ! nuclear hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056076 ! NCOA2_HUMAN [Term] id: CCO:B0068477 name: NCOA2_HUMAN-Phosphoserine716 def: "Protein NCOA2_HUMAN with the residue 716 substituted with Phosphoserine" [UniProtKB:Q15596] comment: By similarity xref: UniProtKB:Q15596 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056076 ! NCOA2_HUMAN [Term] id: CCO:B0068478 name: NCOA3_HUMAN-Phosphoserine214 def: "Protein NCOA3_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q9Y6Q9] xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0068479 name: NCOA3_HUMAN-Phosphoserine551 def: "Protein NCOA3_HUMAN with the residue 551 substituted with Phosphoserine" [UniProtKB:Q9Y6Q9] xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0068480 name: NCOA3_HUMAN-Phosphoserine728 def: "Protein NCOA3_HUMAN with the residue 728 substituted with Phosphoserine" [UniProtKB:Q9Y6Q9] xref: UniProtKB:Q9Y6Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:B0068481 name: NCOA5_HUMAN-Phosphotyrosine127 def: "Protein NCOA5_HUMAN with the residue 127 substituted with Phosphotyrosine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068482 name: NCOA5_HUMAN-Phosphoserine151 def: "Protein NCOA5_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068483 name: NCOA5_HUMAN-Phosphoserine377 def: "Protein NCOA5_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068484 name: NCOA5_HUMAN-Phosphoserine378 def: "Protein NCOA5_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068485 name: NCOA5_HUMAN-Phosphoserine381 def: "Protein NCOA5_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068486 name: NCOA5_HUMAN-Phosphoserine387 def: "Protein NCOA5_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068487 name: NCOA5_HUMAN-Phosphoserine404 def: "Protein NCOA5_HUMAN with the residue 404 substituted with Phosphoserine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068488 name: NCOA5_HUMAN-Phosphothreonine420 def: "Protein NCOA5_HUMAN with the residue 420 substituted with Phosphothreonine" [UniProtKB:Q9HCD5] xref: UniProtKB:Q9HCD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058802 ! NCOA5_HUMAN [Term] id: CCO:B0068489 name: NCOA7_HUMAN-Phosphothreonine134 def: "Protein NCOA7_HUMAN with the residue 134 substituted with Phosphothreonine" [UniProtKB:Q8NI08] xref: UniProtKB:Q8NI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:B0068490 name: NCOA7_HUMAN-Phosphoserine208 def: "Protein NCOA7_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q8NI08] xref: UniProtKB:Q8NI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:B0068491 name: NCOA7_HUMAN-Phosphoserine209 def: "Protein NCOA7_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q8NI08] xref: UniProtKB:Q8NI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:B0068492 name: NCOA7_HUMAN-Phosphothreonine210 def: "Protein NCOA7_HUMAN with the residue 210 substituted with Phosphothreonine" [UniProtKB:Q8NI08] xref: UniProtKB:Q8NI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:B0068493 name: NCOA7_HUMAN-Phosphoserine211 def: "Protein NCOA7_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:Q8NI08] xref: UniProtKB:Q8NI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:B0068494 name: NCOA7_HUMAN-Phosphoserine441 def: "Protein NCOA7_HUMAN with the residue 441 substituted with Phosphoserine" [UniProtKB:Q8NI08] xref: UniProtKB:Q8NI08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:B0068495 name: NCOR1_HUMAN-Phosphoserine158 def: "Protein NCOR1_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068496 name: NCOR1_HUMAN-Phosphoserine172 def: "Protein NCOR1_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068497 name: NCOR1_HUMAN-Phosphoserine224 def: "Protein NCOR1_HUMAN with the residue 224 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068498 name: NCOR1_HUMAN-Phosphoserine999 def: "Protein NCOR1_HUMAN with the residue 999 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068499 name: NCOR1_HUMAN-Phosphoserine1450 def: "Protein NCOR1_HUMAN with the residue 1450 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068500 name: NCOR1_HUMAN-Phosphoserine1472 def: "Protein NCOR1_HUMAN with the residue 1472 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068501 name: NCOR1_HUMAN-Phosphoserine1977 def: "Protein NCOR1_HUMAN with the residue 1977 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068502 name: NCOR1_HUMAN-Phosphoserine2120 def: "Protein NCOR1_HUMAN with the residue 2120 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068503 name: NCOR1_HUMAN-Phosphoserine2151 def: "Protein NCOR1_HUMAN with the residue 2151 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068504 name: NCOR1_HUMAN-Phosphoserine2184 def: "Protein NCOR1_HUMAN with the residue 2184 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068505 name: NCOR1_HUMAN-Phosphotyrosine2432 def: "Protein NCOR1_HUMAN with the residue 2432 substituted with Phosphotyrosine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068506 name: NCOR1_HUMAN-Phosphothreonine2434 def: "Protein NCOR1_HUMAN with the residue 2434 substituted with Phosphothreonine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068507 name: NCOR1_HUMAN-Phosphoserine2436 def: "Protein NCOR1_HUMAN with the residue 2436 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068508 name: NCOR1_HUMAN-Phosphoserine2438 def: "Protein NCOR1_HUMAN with the residue 2438 substituted with Phosphoserine" [UniProtKB:O75376] xref: UniProtKB:O75376 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:B0068509 name: NCOR2_HUMAN-Phosphothreonine156 def: "Protein NCOR2_HUMAN with the residue 156 substituted with Phosphothreonine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068510 name: NCOR2_HUMAN-Phosphoserine745 def: "Protein NCOR2_HUMAN with the residue 745 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068511 name: NCOR2_HUMAN-Phosphoserine746 def: "Protein NCOR2_HUMAN with the residue 746 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068512 name: NCOR2_HUMAN-Phosphoserine750 def: "Protein NCOR2_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068513 name: NCOR2_HUMAN-Phosphoserine753 def: "Protein NCOR2_HUMAN with the residue 753 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068514 name: NCOR2_HUMAN-Phosphoserine1251 def: "Protein NCOR2_HUMAN with the residue 1251 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068515 name: NCOR2_HUMAN-Phosphoserine1479 def: "Protein NCOR2_HUMAN with the residue 1479 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068516 name: NCOR2_HUMAN-Phosphotyrosine2043 def: "Protein NCOR2_HUMAN with the residue 2043 substituted with Phosphotyrosine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068517 name: NCOR2_HUMAN-Phosphoserine2063 def: "Protein NCOR2_HUMAN with the residue 2063 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068518 name: NCOR2_HUMAN-Phosphothreonine2065 def: "Protein NCOR2_HUMAN with the residue 2065 substituted with Phosphothreonine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001414 ! Notch binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068519 name: NCOR2_HUMAN-Phosphoserine2226 def: "Protein NCOR2_HUMAN with the residue 2226 substituted with Phosphoserine" [UniProtKB:Q9Y618] xref: UniProtKB:Q9Y618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:B0068520 name: NCPR_HUMAN-N-acetylglycine2 def: "Protein NCPR_HUMAN with the residue 2 substituted with N-acetylglycine" [UniProtKB:P16435] xref: UniProtKB:P16435 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063530 ! NCPR_HUMAN [Term] id: CCO:B0068521 name: NCPR_HUMAN-Phosphotyrosine575 def: "Protein NCPR_HUMAN with the residue 575 substituted with Phosphotyrosine" [UniProtKB:P16435] comment: By similarity xref: UniProtKB:P16435 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000451 ! NADPH-hemoprotein reductase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0002446 ! FMN binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063530 ! NCPR_HUMAN [Term] id: CCO:B0068522 name: NDE1_HUMAN-Phosphoserine231 def: "Protein NDE1_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0068523 name: NDE1_HUMAN-Phosphoserine239 def: "Protein NDE1_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0068524 name: NDE1_HUMAN-Phosphothreonine240 def: "Protein NDE1_HUMAN with the residue 240 substituted with Phosphothreonine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0068525 name: NDE1_HUMAN-Phosphothreonine243 def: "Protein NDE1_HUMAN with the residue 243 substituted with Phosphothreonine" [UniProtKB:Q9NXR1] xref: UniProtKB:Q9NXR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002173 ! NDE1_HUMAN [Term] id: CCO:B0068526 name: NDF1_HUMAN-Phosphoserine274 def: "Protein NDF1_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q13562] comment: By similarity xref: UniProtKB:Q13562 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055929 ! NDF1_HUMAN [Term] id: CCO:B0068527 name: NDF1_HUMAN-Phosphoserine335 def: "Protein NDF1_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q13562] comment: By similarity xref: UniProtKB:Q13562 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055929 ! NDF1_HUMAN [Term] id: CCO:B0068528 name: NDK5_HUMAN-Phosphotyrosine58 def: "Protein NDK5_HUMAN with the residue 58 substituted with Phosphotyrosine" [UniProtKB:P56597] xref: UniProtKB:P56597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000936 ! nucleoside diphosphate kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0055546 ! NDK5_HUMAN [Term] id: CCO:B0068529 name: NDRG1_HUMAN-Phosphoserine319 def: "Protein NDRG1_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068530 name: NDRG1_HUMAN-Phosphoserine326 def: "Protein NDRG1_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068531 name: NDRG1_HUMAN-Phosphothreonine328 def: "Protein NDRG1_HUMAN with the residue 328 substituted with Phosphothreonine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068532 name: NDRG1_HUMAN-Phosphoserine330 def: "Protein NDRG1_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068533 name: NDRG1_HUMAN-Phosphoserine332 def: "Protein NDRG1_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068534 name: NDRG1_HUMAN-Phosphoserine333 def: "Protein NDRG1_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068535 name: NDRG1_HUMAN-Phosphothreonine335 def: "Protein NDRG1_HUMAN with the residue 335 substituted with Phosphothreonine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068536 name: NDRG1_HUMAN-Phosphoserine336 def: "Protein NDRG1_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068537 name: NDRG1_HUMAN-Phosphoserine364 def: "Protein NDRG1_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068538 name: NDRG1_HUMAN-Phosphothreonine366 def: "Protein NDRG1_HUMAN with the residue 366 substituted with Phosphothreonine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068539 name: NDRG1_HUMAN-Phosphothreonine375 def: "Protein NDRG1_HUMAN with the residue 375 substituted with Phosphothreonine" [UniProtKB:Q92597] xref: UniProtKB:Q92597 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:B0068540 name: NDRG3_HUMAN-Phosphothreonine322 def: "Protein NDRG3_HUMAN with the residue 322 substituted with Phosphothreonine" [UniProtKB:Q9UGV2] xref: UniProtKB:Q9UGV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059128 ! NDRG3_HUMAN [Term] id: CCO:B0068541 name: NDRG3_HUMAN-Phosphoserine331 def: "Protein NDRG3_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q9UGV2] xref: UniProtKB:Q9UGV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059128 ! NDRG3_HUMAN [Term] id: CCO:B0068542 name: NDRG3_HUMAN-Phosphothreonine332 def: "Protein NDRG3_HUMAN with the residue 332 substituted with Phosphothreonine" [UniProtKB:Q9UGV2] xref: UniProtKB:Q9UGV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059128 ! NDRG3_HUMAN [Term] id: CCO:B0068543 name: NDRG3_HUMAN-Phosphoserine334 def: "Protein NDRG3_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q9UGV2] xref: UniProtKB:Q9UGV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059128 ! NDRG3_HUMAN [Term] id: CCO:B0068544 name: NDRG3_HUMAN-Phosphoserine335 def: "Protein NDRG3_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q9UGV2] xref: UniProtKB:Q9UGV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059128 ! NDRG3_HUMAN [Term] id: CCO:B0068545 name: NDRG3_HUMAN-Phosphoserine352 def: "Protein NDRG3_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q9UGV2] xref: UniProtKB:Q9UGV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059128 ! NDRG3_HUMAN [Term] id: CCO:B0068546 name: NDRG3_HUMAN-Phosphoserine374 def: "Protein NDRG3_HUMAN with the residue 374 substituted with Phosphoserine" [UniProtKB:Q9UGV2] xref: UniProtKB:Q9UGV2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059128 ! NDRG3_HUMAN [Term] id: CCO:B0068547 name: NDUA6_HUMAN-N-acetylalanine2 def: "Protein NDUA6_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P56556] comment: By similarity xref: UniProtKB:P56556 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001359 ! mitochondrial membrane relationship: transformation_of CCO:B0063422 ! NDUA6_HUMAN [Term] id: CCO:B0068548 name: NDUA7_HUMAN-N-acetylalanine2 def: "Protein NDUA7_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O95182] comment: By similarity xref: UniProtKB:O95182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063477 ! NDUA7_HUMAN [Term] id: CCO:B0068549 name: NDUA7_HUMAN-Phosphoserine63 def: "Protein NDUA7_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:O95182] xref: UniProtKB:O95182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063477 ! NDUA7_HUMAN [Term] id: CCO:B0068550 name: NDUAD_HUMAN-N-acetylalanine2 def: "Protein NDUAD_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9P0J0] comment: By similarity xref: UniProtKB:Q9P0J0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059028 ! NDUAD_HUMAN [Term] id: CCO:B0068551 name: NDUB9_HUMAN-N-acetylalanine2 def: "Protein NDUB9_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9Y6M9] xref: UniProtKB:Q9Y6M9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063423 ! NDUB9_HUMAN [Term] id: CCO:B0068552 name: NDUS4_HUMAN-Phosphothreonine32 def: "Protein NDUS4_HUMAN with the residue 32 substituted with Phosphothreonine" [UniProtKB:O43181] xref: UniProtKB:O43181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054454 ! NDUS4_HUMAN [Term] id: CCO:B0068553 name: NDUS4_HUMAN-Phosphoserine34 def: "Protein NDUS4_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:O43181] xref: UniProtKB:O43181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054454 ! NDUS4_HUMAN [Term] id: CCO:B0068554 name: NDUV1_HUMAN-N6-acetyllysine81 def: "Protein NDUV1_HUMAN with the residue 81 substituted with N6-acetyllysine" [UniProtKB:P49821] comment: By similarity xref: UniProtKB:P49821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000447 ! NADH dehydrogenase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001740 ! NADH dehydrogenase (ubiquinone) activity relationship: has_function CCO:F0002446 ! FMN binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008141 ! 4 iron, 4 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000332 ! mitochondrial respiratory chain relationship: located_in CCO:C0000333 ! mitochondrial respiratory chain complex I relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0062888 ! NDUV1_HUMAN [Term] id: CCO:B0068555 name: NDUV1_HUMAN-N6-acetyllysine104 def: "Protein NDUV1_HUMAN with the residue 104 substituted with N6-acetyllysine" [UniProtKB:P49821] comment: By similarity xref: UniProtKB:P49821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062888 ! NDUV1_HUMAN [Term] id: CCO:B0068556 name: NDUV1_HUMAN-N6-acetyllysine375 def: "Protein NDUV1_HUMAN with the residue 375 substituted with N6-acetyllysine" [UniProtKB:P49821] comment: By similarity xref: UniProtKB:P49821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062888 ! NDUV1_HUMAN [Term] id: CCO:B0068557 name: NEB2_HUMAN-Phosphothreonine205 def: "Protein NEB2_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:Q96SB3] xref: UniProtKB:Q96SB3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:B0068558 name: NED4L_HUMAN-Phosphothreonine318 def: "Protein NED4L_HUMAN with the residue 318 substituted with Phosphothreonine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0068559 name: NED4L_HUMAN-Phosphoserine449 def: "Protein NED4L_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0003551 ! sodium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0068560 name: NED4L_HUMAN-Phosphoserine464 def: "Protein NED4L_HUMAN with the residue 464 substituted with Phosphoserine" [UniProtKB:Q96PU5] xref: UniProtKB:Q96PU5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:B0068561 name: NEK4_HUMAN-Phosphoserine484 def: "Protein NEK4_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:P51957] xref: UniProtKB:P51957 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001655 ! NEK4_HUMAN [Term] id: CCO:B0068562 name: NELFA_HUMAN-Phosphothreonine157 def: "Protein NELFA_HUMAN with the residue 157 substituted with Phosphothreonine" [UniProtKB:Q9H3P2] xref: UniProtKB:Q9H3P2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058707 ! NELFA_HUMAN [Term] id: CCO:B0068563 name: NELFA_HUMAN-Phosphoserine233 def: "Protein NELFA_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:Q9H3P2] xref: UniProtKB:Q9H3P2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0058707 ! NELFA_HUMAN [Term] id: CCO:B0068564 name: NELFA_HUMAN-Phosphoserine363 def: "Protein NELFA_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q9H3P2] xref: UniProtKB:Q9H3P2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058707 ! NELFA_HUMAN [Term] id: CCO:B0068565 name: NELFA_HUMAN-Phosphothreonine365 def: "Protein NELFA_HUMAN with the residue 365 substituted with Phosphothreonine" [UniProtKB:Q9H3P2] xref: UniProtKB:Q9H3P2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058707 ! NELFA_HUMAN [Term] id: CCO:B0068566 name: NELFB_HUMAN-Phosphoserine557 def: "Protein NELFB_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:Q8WX92] xref: UniProtKB:Q8WX92 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058011 ! NELFB_HUMAN [Term] id: CCO:B0068567 name: NELFE_HUMAN-Phosphoserine51 def: "Protein NELFE_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P18615] xref: UniProtKB:P18615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:B0068568 name: NELFE_HUMAN-Phosphoserine115 def: "Protein NELFE_HUMAN with the residue 115 substituted with Phosphoserine" [UniProtKB:P18615] xref: UniProtKB:P18615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:B0068569 name: NELFE_HUMAN-Phosphoserine131 def: "Protein NELFE_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:P18615] xref: UniProtKB:P18615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:B0068570 name: NELFE_HUMAN-Phosphoserine181 def: "Protein NELFE_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:P18615] xref: UniProtKB:P18615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:B0068571 name: NELFE_HUMAN-Phosphoserine191 def: "Protein NELFE_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:P18615] xref: UniProtKB:P18615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:B0068572 name: NELFE_HUMAN-Phosphoserine281 def: "Protein NELFE_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:P18615] xref: UniProtKB:P18615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:B0068573 name: NELFE_HUMAN-Phosphoserine353 def: "Protein NELFE_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:P18615] xref: UniProtKB:P18615 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:B0068574 name: NEMO_HUMAN-Phosphoserine377 def: "Protein NEMO_HUMAN with the residue 377 substituted with Phosphoserine" [UniProtKB:Q9Y6K9] xref: UniProtKB:Q9Y6K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:B0068575 name: NEMO_HUMAN-Phosphoserine387 def: "Protein NEMO_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q9Y6K9] xref: UniProtKB:Q9Y6K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:B0068576 name: NEU1_HUMAN-Glycine amide28 def: "Protein NEU1_HUMAN with the residue 28 substituted with Glycine amide" [UniProtKB:P01178] xref: UniProtKB:P01178 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017141 ! NEU1_HUMAN [Term] id: CCO:B0068577 name: NEU2_HUMAN-Glycine amide28 def: "Protein NEU2_HUMAN with the residue 28 substituted with Glycine amide" [UniProtKB:P01185] xref: UniProtKB:P01185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_function CCO:F0001482 ! neurohypophyseal hormone activity relationship: has_function CCO:F0004866 ! oxytocin receptor binding relationship: has_function CCO:F0004902 ! V1A vasopressin receptor binding relationship: has_function CCO:F0004903 ! V1B vasopressin receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0017140 ! NEU2_HUMAN [Term] id: CCO:B0068578 name: NEUG_HUMAN-N-acetylmethionine1 def: "Protein NEUG_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q92686] comment: By similarity xref: UniProtKB:Q92686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058082 ! NEUG_HUMAN [Term] id: CCO:B0068579 name: NEUG_HUMAN-Phosphoserine36 def: "Protein NEUG_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q92686] comment: by PKC; By similarity xref: UniProtKB:Q92686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058082 ! NEUG_HUMAN [Term] id: CCO:B0068580 name: NEUM_HUMAN-Phosphoserine41 def: "Protein NEUM_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:P17677] comment: By similarity xref: UniProtKB:P17677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0055091 ! NEUM_HUMAN [Term] id: CCO:B0068581 name: NEUM_HUMAN-Phosphothreonine94 def: "Protein NEUM_HUMAN with the residue 94 substituted with Phosphothreonine" [UniProtKB:P17677] comment: By similarity xref: UniProtKB:P17677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055091 ! NEUM_HUMAN [Term] id: CCO:B0068582 name: NEUM_HUMAN-Phosphothreonine181 def: "Protein NEUM_HUMAN with the residue 181 substituted with Phosphothreonine" [UniProtKB:P17677] comment: By similarity xref: UniProtKB:P17677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055091 ! NEUM_HUMAN [Term] id: CCO:B0068583 name: NEUM_HUMAN-Phosphoserine202 def: "Protein NEUM_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:P17677] comment: by CK2; By similarity xref: UniProtKB:P17677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055091 ! NEUM_HUMAN [Term] id: CCO:B0068584 name: NEUM_HUMAN-Phosphoserine203 def: "Protein NEUM_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:P17677] comment: by CK2; By similarity xref: UniProtKB:P17677 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055091 ! NEUM_HUMAN [Term] id: CCO:B0068585 name: NEXN_HUMAN-Phosphoserine80 def: "Protein NEXN_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q0ZGT2] xref: UniProtKB:Q0ZGT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055833 ! NEXN_HUMAN [Term] id: CCO:B0068586 name: NEXN_HUMAN-Phosphoserine357 def: "Protein NEXN_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q0ZGT2] xref: UniProtKB:Q0ZGT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055833 ! NEXN_HUMAN [Term] id: CCO:B0068587 name: NEXN_HUMAN-Phosphoserine365 def: "Protein NEXN_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q0ZGT2] xref: UniProtKB:Q0ZGT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000476 ! cell-substrate adherens junction relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0055833 ! NEXN_HUMAN [Term] id: CCO:B0068588 name: NEXN_HUMAN-Phosphothreonine370 def: "Protein NEXN_HUMAN with the residue 370 substituted with Phosphothreonine" [UniProtKB:Q0ZGT2] xref: UniProtKB:Q0ZGT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055833 ! NEXN_HUMAN [Term] id: CCO:B0068589 name: NEXN_HUMAN-Phosphoserine569 def: "Protein NEXN_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q0ZGT2] xref: UniProtKB:Q0ZGT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055833 ! NEXN_HUMAN [Term] id: CCO:B0068590 name: NF1_HUMAN-Phosphotyrosine2476 def: "Protein NF1_HUMAN with the residue 2476 substituted with Phosphotyrosine" [UniProtKB:P21359] xref: UniProtKB:P21359 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:B0068591 name: NF2IP_HUMAN-Phosphoserine88 def: "Protein NF2IP_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068592 name: NF2IP_HUMAN-Phosphoserine90 def: "Protein NF2IP_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068593 name: NF2IP_HUMAN-Phosphoserine92 def: "Protein NF2IP_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068594 name: NF2IP_HUMAN-Phosphoserine127 def: "Protein NF2IP_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068595 name: NF2IP_HUMAN-Phosphoserine198 def: "Protein NF2IP_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068596 name: NF2IP_HUMAN-Phosphoserine201 def: "Protein NF2IP_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068597 name: NF2IP_HUMAN-Phosphoserine204 def: "Protein NF2IP_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068598 name: NF2IP_HUMAN-Phosphothreonine316 def: "Protein NF2IP_HUMAN with the residue 316 substituted with Phosphothreonine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068599 name: NF2IP_HUMAN-Phosphoserine369 def: "Protein NF2IP_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068600 name: NF2IP_HUMAN-Phosphoserine390 def: "Protein NF2IP_HUMAN with the residue 390 substituted with Phosphoserine" [UniProtKB:Q8NCF5] xref: UniProtKB:Q8NCF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057565 ! NF2IP_HUMAN [Term] id: CCO:B0068601 name: NF2L1_HUMAN-Phosphotyrosine645 def: "Protein NF2L1_HUMAN with the residue 645 substituted with Phosphotyrosine" [UniProtKB:Q14494] xref: UniProtKB:Q14494 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032380 ! NF2L1_HUMAN [Term] id: CCO:B0068602 name: NF2L2_HUMAN-Phosphoserine40 def: "Protein NF2L2_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q16236] comment: by PKC; xref: UniProtKB:Q16236 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056129 ! NF2L2_HUMAN [Term] id: CCO:B0068603 name: NFAC1_HUMAN-Phosphoserine117 def: "Protein NFAC1_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:O95644] xref: UniProtKB:O95644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001658 ! FK506 binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054779 ! NFAC1_HUMAN [Term] id: CCO:B0068604 name: NFAC2_HUMAN-Phosphoserine53 def: "Protein NFAC2_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068605 name: NFAC2_HUMAN-Phosphoserine56 def: "Protein NFAC2_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068606 name: NFAC2_HUMAN-Phosphoserine99 def: "Protein NFAC2_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068607 name: NFAC2_HUMAN-Phosphoserine110 def: "Protein NFAC2_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068608 name: NFAC2_HUMAN-Phosphoserine168 def: "Protein NFAC2_HUMAN with the residue 168 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068609 name: NFAC2_HUMAN-Phosphoserine171 def: "Protein NFAC2_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068610 name: NFAC2_HUMAN-Phosphoserine172 def: "Protein NFAC2_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068611 name: NFAC2_HUMAN-Phosphoserine174 def: "Protein NFAC2_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068612 name: NFAC2_HUMAN-Phosphoserine175 def: "Protein NFAC2_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068613 name: NFAC2_HUMAN-Phosphoserine177 def: "Protein NFAC2_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068614 name: NFAC2_HUMAN-Phosphoserine180 def: "Protein NFAC2_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068615 name: NFAC2_HUMAN-Phosphoserine213 def: "Protein NFAC2_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068616 name: NFAC2_HUMAN-Phosphoserine217 def: "Protein NFAC2_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068617 name: NFAC2_HUMAN-Phosphoserine221 def: "Protein NFAC2_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068618 name: NFAC2_HUMAN-Phosphoserine236 def: "Protein NFAC2_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068619 name: NFAC2_HUMAN-Phosphoserine243 def: "Protein NFAC2_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068620 name: NFAC2_HUMAN-Phosphoserine268 def: "Protein NFAC2_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068621 name: NFAC2_HUMAN-Phosphoserine274 def: "Protein NFAC2_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068622 name: NFAC2_HUMAN-Phosphoserine276 def: "Protein NFAC2_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068623 name: NFAC2_HUMAN-Phosphoserine280 def: "Protein NFAC2_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068624 name: NFAC2_HUMAN-Phosphoserine326 def: "Protein NFAC2_HUMAN with the residue 326 substituted with Phosphoserine" [UniProtKB:Q13469] xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068625 name: NFAC2_HUMAN-Phosphoserine330 def: "Protein NFAC2_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q13469] xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068626 name: NFAC2_HUMAN-Phosphoserine363 def: "Protein NFAC2_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q13469] comment: By similarity xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068627 name: NFAC2_HUMAN-Phosphothreonine585 def: "Protein NFAC2_HUMAN with the residue 585 substituted with Phosphothreonine" [UniProtKB:Q13469] xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068628 name: NFAC2_HUMAN-Phosphothreonine599 def: "Protein NFAC2_HUMAN with the residue 599 substituted with Phosphothreonine" [UniProtKB:Q13469] xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068629 name: NFAC2_HUMAN-Phosphoserine605 def: "Protein NFAC2_HUMAN with the residue 605 substituted with Phosphoserine" [UniProtKB:Q13469] xref: UniProtKB:Q13469 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:B0068630 name: NFAC4_HUMAN-Phosphoserine272 def: "Protein NFAC4_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q14934] xref: UniProtKB:Q14934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056026 ! NFAC4_HUMAN [Term] id: CCO:B0068631 name: NFAC4_HUMAN-Phosphoserine289 def: "Protein NFAC4_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q14934] xref: UniProtKB:Q14934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056026 ! NFAC4_HUMAN [Term] id: CCO:B0068632 name: NFAC4_HUMAN-Phosphoserine334 def: "Protein NFAC4_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q14934] xref: UniProtKB:Q14934 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056026 ! NFAC4_HUMAN [Term] id: CCO:B0068633 name: NFAM1_HUMAN-Phosphotyrosine220 def: "Protein NFAM1_HUMAN with the residue 220 substituted with Phosphotyrosine" [UniProtKB:Q8NET5] comment: Probable xref: UniProtKB:Q8NET5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057595 ! NFAM1_HUMAN [Term] id: CCO:B0068634 name: NFAM1_HUMAN-Phosphotyrosine231 def: "Protein NFAM1_HUMAN with the residue 231 substituted with Phosphotyrosine" [UniProtKB:Q8NET5] comment: Probable xref: UniProtKB:Q8NET5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057595 ! NFAM1_HUMAN [Term] id: CCO:B0068635 name: NFIA_HUMAN-Phosphoserine258 def: "Protein NFIA_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q12857] xref: UniProtKB:Q12857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0025416 ! NFIA_HUMAN [Term] id: CCO:B0068636 name: NFIA_HUMAN-Phosphoserine265 def: "Protein NFIA_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q12857] xref: UniProtKB:Q12857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025416 ! NFIA_HUMAN [Term] id: CCO:B0068637 name: NFIA_HUMAN-Phosphoserine280 def: "Protein NFIA_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q12857] xref: UniProtKB:Q12857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025416 ! NFIA_HUMAN [Term] id: CCO:B0068638 name: NFIA_HUMAN-Phosphoserine287 def: "Protein NFIA_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q12857] xref: UniProtKB:Q12857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025416 ! NFIA_HUMAN [Term] id: CCO:B0068639 name: NFIA_HUMAN-Phosphoserine300 def: "Protein NFIA_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q12857] xref: UniProtKB:Q12857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025416 ! NFIA_HUMAN [Term] id: CCO:B0068640 name: NFIA_HUMAN-Phosphoserine305 def: "Protein NFIA_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q12857] xref: UniProtKB:Q12857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025416 ! NFIA_HUMAN [Term] id: CCO:B0068641 name: NFIA_HUMAN-Phosphoserine319 def: "Protein NFIA_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q12857] xref: UniProtKB:Q12857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025416 ! NFIA_HUMAN [Term] id: CCO:B0068642 name: NFIB_HUMAN-Phosphoserine63 def: "Protein NFIB_HUMAN with the residue 63 substituted with Phosphoserine" [UniProtKB:O00712] comment: By similarity xref: UniProtKB:O00712 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025414 ! NFIB_HUMAN [Term] id: CCO:B0068643 name: NFIB_HUMAN-Phosphoserine264 def: "Protein NFIB_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:O00712] comment: By similarity xref: UniProtKB:O00712 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025414 ! NFIB_HUMAN [Term] id: CCO:B0068644 name: NFIB_HUMAN-Phosphoserine292 def: "Protein NFIB_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:O00712] comment: By similarity xref: UniProtKB:O00712 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0025414 ! NFIB_HUMAN [Term] id: CCO:B0068645 name: NFIB_HUMAN-Phosphoserine295 def: "Protein NFIB_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:O00712] comment: By similarity xref: UniProtKB:O00712 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025414 ! NFIB_HUMAN [Term] id: CCO:B0068646 name: NFIC_HUMAN-Phosphoserine4 def: "Protein NFIC_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068647 name: NFIC_HUMAN-Phosphoserine194 def: "Protein NFIC_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068648 name: NFIC_HUMAN-Phosphoserine304 def: "Protein NFIC_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068649 name: NFIC_HUMAN-Phosphoserine305 def: "Protein NFIC_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068650 name: NFIC_HUMAN-Phosphoserine323 def: "Protein NFIC_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068651 name: NFIC_HUMAN-Phosphoserine333 def: "Protein NFIC_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068652 name: NFIC_HUMAN-Phosphoserine337 def: "Protein NFIC_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:P08651] comment: By similarity xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068653 name: NFIC_HUMAN-Phosphoserine339 def: "Protein NFIC_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068654 name: NFIC_HUMAN-Phosphoserine343 def: "Protein NFIC_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:P08651] xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068655 name: NFIC_HUMAN-Phosphothreonine378 def: "Protein NFIC_HUMAN with the residue 378 substituted with Phosphothreonine" [UniProtKB:P08651] comment: By similarity xref: UniProtKB:P08651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025412 ! NFIC_HUMAN [Term] id: CCO:B0068656 name: NFIL3_HUMAN-Phosphoserine286 def: "Protein NFIL3_HUMAN with the residue 286 substituted with Phosphoserine" [UniProtKB:Q16649] comment: By similarity xref: UniProtKB:Q16649 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056167 ! NFIL3_HUMAN [Term] id: CCO:B0068657 name: NFIL3_HUMAN-Phosphoserine301 def: "Protein NFIL3_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:Q16649] xref: UniProtKB:Q16649 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056167 ! NFIL3_HUMAN [Term] id: CCO:B0068658 name: NFIX_HUMAN-Phosphoserine280 def: "Protein NFIX_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q14938] xref: UniProtKB:Q14938 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025407 ! NFIX_HUMAN [Term] id: CCO:B0068659 name: NFIX_HUMAN-Phosphoserine284 def: "Protein NFIX_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q14938] comment: By similarity xref: UniProtKB:Q14938 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025407 ! NFIX_HUMAN [Term] id: CCO:B0068660 name: NFIX_HUMAN-Phosphoserine288 def: "Protein NFIX_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q14938] comment: By similarity xref: UniProtKB:Q14938 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025407 ! NFIX_HUMAN [Term] id: CCO:B0068661 name: NFKB1_HUMAN-S-nitrosocysteine61 def: "Protein NFKB1_HUMAN with the residue 61 substituted with S-nitrosocysteine" [UniProtKB:P19838] xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068662 name: NFKB1_HUMAN-Phosphoserine337 def: "Protein NFKB1_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:P19838] comment: by PKA; Potential xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068663 name: NFKB1_HUMAN-N6-acetyllysine431 def: "Protein NFKB1_HUMAN with the residue 431 substituted with N6-acetyllysine" [UniProtKB:P19838] comment: by EP300; Probable xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068664 name: NFKB1_HUMAN-N6-acetyllysine440 def: "Protein NFKB1_HUMAN with the residue 440 substituted with N6-acetyllysine" [UniProtKB:P19838] comment: by EP300; Probable xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068665 name: NFKB1_HUMAN-N6-acetyllysine441 def: "Protein NFKB1_HUMAN with the residue 441 substituted with N6-acetyllysine" [UniProtKB:P19838] comment: by EP300; Probable xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068666 name: NFKB1_HUMAN-Phosphoserine903 def: "Protein NFKB1_HUMAN with the residue 903 substituted with Phosphoserine" [UniProtKB:P19838] comment: by GSK3-beta; in vitro; xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068667 name: NFKB1_HUMAN-Phosphoserine907 def: "Protein NFKB1_HUMAN with the residue 907 substituted with Phosphoserine" [UniProtKB:P19838] comment: by GSK3-beta; in vitro; xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068668 name: NFKB1_HUMAN-Phosphoserine927 def: "Protein NFKB1_HUMAN with the residue 927 substituted with Phosphoserine" [UniProtKB:P19838] comment: by IKKB; xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068669 name: NFKB1_HUMAN-Phosphoserine932 def: "Protein NFKB1_HUMAN with the residue 932 substituted with Phosphoserine" [UniProtKB:P19838] comment: by IKKB; xref: UniProtKB:P19838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:B0068670 name: NFKB2_HUMAN-Phosphothreonine429 def: "Protein NFKB2_HUMAN with the residue 429 substituted with Phosphothreonine" [UniProtKB:Q00653] xref: UniProtKB:Q00653 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:B0068671 name: NFM_HUMAN-N-acetylserine2 def: "Protein NFM_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P07197] comment: By similarity xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068672 name: NFM_HUMAN-Phosphotyrosine320 def: "Protein NFM_HUMAN with the residue 320 substituted with Phosphotyrosine" [UniProtKB:P07197] comment: By similarity xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068673 name: NFM_HUMAN-Phosphoserine511 def: "Protein NFM_HUMAN with the residue 511 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068674 name: NFM_HUMAN-Phosphoserine545 def: "Protein NFM_HUMAN with the residue 545 substituted with Phosphoserine" [UniProtKB:P07197] comment: By similarity xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068675 name: NFM_HUMAN-Phosphoserine553 def: "Protein NFM_HUMAN with the residue 553 substituted with Phosphoserine" [UniProtKB:P07197] comment: By similarity xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068676 name: NFM_HUMAN-Phosphoserine559 def: "Protein NFM_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:P07197] comment: By similarity xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068677 name: NFM_HUMAN-Phosphoserine615 def: "Protein NFM_HUMAN with the residue 615 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068678 name: NFM_HUMAN-Phosphoserine620 def: "Protein NFM_HUMAN with the residue 620 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068679 name: NFM_HUMAN-Phosphoserine628 def: "Protein NFM_HUMAN with the residue 628 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068680 name: NFM_HUMAN-Phosphoserine633 def: "Protein NFM_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068681 name: NFM_HUMAN-Phosphoserine654 def: "Protein NFM_HUMAN with the residue 654 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000440 ! intermediate filament relationship: located_in CCO:C0000441 ! neurofilament relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001300 ! neuromuscular junction relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068682 name: NFM_HUMAN-Phosphoserine659 def: "Protein NFM_HUMAN with the residue 659 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068683 name: NFM_HUMAN-Phosphoserine667 def: "Protein NFM_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068684 name: NFM_HUMAN-Phosphoserine672 def: "Protein NFM_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068685 name: NFM_HUMAN-Phosphoserine680 def: "Protein NFM_HUMAN with the residue 680 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068686 name: NFM_HUMAN-Phosphoserine685 def: "Protein NFM_HUMAN with the residue 685 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068687 name: NFM_HUMAN-Phosphoserine736 def: "Protein NFM_HUMAN with the residue 736 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068688 name: NFM_HUMAN-Phosphoserine783 def: "Protein NFM_HUMAN with the residue 783 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068689 name: NFM_HUMAN-Phosphoserine788 def: "Protein NFM_HUMAN with the residue 788 substituted with Phosphoserine" [UniProtKB:P07197] xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068690 name: NFM_HUMAN-Phosphoserine837 def: "Protein NFM_HUMAN with the residue 837 substituted with Phosphoserine" [UniProtKB:P07197] comment: By similarity xref: UniProtKB:P07197 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:B0068691 name: NFX1_HUMAN-Phosphoserine49 def: "Protein NFX1_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:Q12986] xref: UniProtKB:Q12986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055863 ! NFX1_HUMAN [Term] id: CCO:B0068692 name: NFX1_HUMAN-Phosphoserine50 def: "Protein NFX1_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q12986] xref: UniProtKB:Q12986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055863 ! NFX1_HUMAN [Term] id: CCO:B0068693 name: NFX1_HUMAN-Phosphotyrosine1041 def: "Protein NFX1_HUMAN with the residue 1041 substituted with Phosphotyrosine" [UniProtKB:Q12986] xref: UniProtKB:Q12986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055863 ! NFX1_HUMAN [Term] id: CCO:B0068694 name: NFXL1_HUMAN-Phosphoserine50 def: "Protein NFXL1_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q6ZNB6] xref: UniProtKB:Q6ZNB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057019 ! NFXL1_HUMAN [Term] id: CCO:B0068695 name: NFXL1_HUMAN-Phosphoserine65 def: "Protein NFXL1_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q6ZNB6] xref: UniProtKB:Q6ZNB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057019 ! NFXL1_HUMAN [Term] id: CCO:B0068696 name: NFXL1_HUMAN-Phosphoserine106 def: "Protein NFXL1_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q6ZNB6] xref: UniProtKB:Q6ZNB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057019 ! NFXL1_HUMAN [Term] id: CCO:B0068697 name: NFXL1_HUMAN-Phosphoserine107 def: "Protein NFXL1_HUMAN with the residue 107 substituted with Phosphoserine" [UniProtKB:Q6ZNB6] xref: UniProtKB:Q6ZNB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057019 ! NFXL1_HUMAN [Term] id: CCO:B0068698 name: NFXL1_HUMAN-Phosphoserine108 def: "Protein NFXL1_HUMAN with the residue 108 substituted with Phosphoserine" [UniProtKB:Q6ZNB6] xref: UniProtKB:Q6ZNB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057019 ! NFXL1_HUMAN [Term] id: CCO:B0068699 name: NFXL1_HUMAN-Phosphoserine109 def: "Protein NFXL1_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q6ZNB6] xref: UniProtKB:Q6ZNB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057019 ! NFXL1_HUMAN [Term] id: CCO:B0068700 name: NGAP_HUMAN-Phosphoserine16 def: "Protein NGAP_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q9UJF2] xref: UniProtKB:Q9UJF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019350 ! NGAP_HUMAN [Term] id: CCO:B0068701 name: NGAP_HUMAN-Phosphoserine663 def: "Protein NGAP_HUMAN with the residue 663 substituted with Phosphoserine" [UniProtKB:Q9UJF2] xref: UniProtKB:Q9UJF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019350 ! NGAP_HUMAN [Term] id: CCO:B0068702 name: NGDN_HUMAN-Phosphoserine142 def: "Protein NGDN_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q8NEJ9] xref: UniProtKB:Q8NEJ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057591 ! NGDN_HUMAN [Term] id: CCO:B0068703 name: NGDN_HUMAN-Phosphoserine143 def: "Protein NGDN_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:Q8NEJ9] xref: UniProtKB:Q8NEJ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057591 ! NGDN_HUMAN [Term] id: CCO:B0068704 name: NGEF_HUMAN-Phosphotyrosine179 def: "Protein NGEF_HUMAN with the residue 179 substituted with Phosphotyrosine" [UniProtKB:Q8N5V2] comment: By similarity xref: UniProtKB:Q8N5V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0057480 ! NGEF_HUMAN [Term] id: CCO:B0068705 name: NGEF_HUMAN-Phosphoserine606 def: "Protein NGEF_HUMAN with the residue 606 substituted with Phosphoserine" [UniProtKB:Q8N5V2] comment: By similarity xref: UniProtKB:Q8N5V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057480 ! NGEF_HUMAN [Term] id: CCO:B0068706 name: NGF_HUMAN-Phosphoserine84 def: "Protein NGF_HUMAN with the residue 84 substituted with Phosphoserine" [UniProtKB:P01138] xref: UniProtKB:P01138 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001464 ! nerve growth factor receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000377 ! Golgi lumen relationship: transformation_of CCO:B0054834 ! NGF_HUMAN [Term] id: CCO:B0068707 name: NHERF_HUMAN-N-acetylserine2 def: "Protein NHERF_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:O14745] xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068708 name: NHERF_HUMAN-Phosphoserine280 def: "Protein NHERF_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:O14745] xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068709 name: NHERF_HUMAN-Phosphoserine288 def: "Protein NHERF_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:O14745] comment: By similarity xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004711 ! beta-2 adrenergic receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068710 name: NHERF_HUMAN-Phosphoserine290 def: "Protein NHERF_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:O14745] xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068711 name: NHERF_HUMAN-Phosphoserine291 def: "Protein NHERF_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:O14745] xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068712 name: NHERF_HUMAN-Phosphothreonine293 def: "Protein NHERF_HUMAN with the residue 293 substituted with Phosphothreonine" [UniProtKB:O14745] xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068713 name: NHERF_HUMAN-Phosphoserine294 def: "Protein NHERF_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:O14745] comment: By similarity xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068714 name: NHERF_HUMAN-Phosphoserine302 def: "Protein NHERF_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:O14745] comment: By similarity xref: UniProtKB:O14745 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:B0068715 name: NHRF2_HUMAN-Phosphoserine183 def: "Protein NHRF2_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q15599] xref: UniProtKB:Q15599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0025069 ! NHRF2_HUMAN [Term] id: CCO:B0068716 name: NHRF2_HUMAN-Phosphoserine254 def: "Protein NHRF2_HUMAN with the residue 254 substituted with Phosphoserine" [UniProtKB:Q15599] xref: UniProtKB:Q15599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025069 ! NHRF2_HUMAN [Term] id: CCO:B0068717 name: NHRF2_HUMAN-Phosphoserine272 def: "Protein NHRF2_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q15599] comment: By similarity xref: UniProtKB:Q15599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025069 ! NHRF2_HUMAN [Term] id: CCO:B0068718 name: NHRF2_HUMAN-Phosphoserine275 def: "Protein NHRF2_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:Q15599] xref: UniProtKB:Q15599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025069 ! NHRF2_HUMAN [Term] id: CCO:B0068719 name: NIN_HUMAN-Phosphoserine1550 def: "Protein NIN_HUMAN with the residue 1550 substituted with Phosphoserine" [UniProtKB:Q8N4C6] xref: UniProtKB:Q8N4C6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062970 ! NIN_HUMAN [Term] id: CCO:B0068720 name: NIPA_HUMAN-Phosphothreonine333 def: "Protein NIPA_HUMAN with the residue 333 substituted with Phosphothreonine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068721 name: NIPA_HUMAN-Phosphoserine335 def: "Protein NIPA_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068722 name: NIPA_HUMAN-Phosphoserine338 def: "Protein NIPA_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068723 name: NIPA_HUMAN-Phosphoserine344 def: "Protein NIPA_HUMAN with the residue 344 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068724 name: NIPA_HUMAN-Phosphoserine357 def: "Protein NIPA_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068725 name: NIPA_HUMAN-Phosphothreonine384 def: "Protein NIPA_HUMAN with the residue 384 substituted with Phosphothreonine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068726 name: NIPA_HUMAN-Phosphothreonine387 def: "Protein NIPA_HUMAN with the residue 387 substituted with Phosphothreonine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068727 name: NIPA_HUMAN-Phosphoserine394 def: "Protein NIPA_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q86WB0] xref: UniProtKB:Q86WB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001941 ! NIPA_HUMAN [Term] id: CCO:B0068728 name: NIPBL_HUMAN-Phosphoserine139 def: "Protein NIPBL_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068729 name: NIPBL_HUMAN-Phosphoserine150 def: "Protein NIPBL_HUMAN with the residue 150 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068730 name: NIPBL_HUMAN-Phosphoserine162 def: "Protein NIPBL_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068731 name: NIPBL_HUMAN-Phosphoserine306 def: "Protein NIPBL_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068732 name: NIPBL_HUMAN-Phosphoserine350 def: "Protein NIPBL_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068733 name: NIPBL_HUMAN-Phosphoserine1160 def: "Protein NIPBL_HUMAN with the residue 1160 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068734 name: NIPBL_HUMAN-Phosphoserine2509 def: "Protein NIPBL_HUMAN with the residue 2509 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068735 name: NIPBL_HUMAN-Phosphoserine2511 def: "Protein NIPBL_HUMAN with the residue 2511 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068736 name: NIPBL_HUMAN-Phosphoserine2513 def: "Protein NIPBL_HUMAN with the residue 2513 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068737 name: NIPBL_HUMAN-Phosphoserine2515 def: "Protein NIPBL_HUMAN with the residue 2515 substituted with Phosphoserine" [UniProtKB:Q6KC79] xref: UniProtKB:Q6KC79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001908 ! NIPBL_HUMAN [Term] id: CCO:B0068738 name: NLK_HUMAN-Phosphothreonine286 def: "Protein NLK_HUMAN with the residue 286 substituted with Phosphothreonine" [UniProtKB:Q9UBE8] comment: By similarity xref: UniProtKB:Q9UBE8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001073 ! MAP kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:B0068739 name: NLK_HUMAN-Phosphothreonine291 def: "Protein NLK_HUMAN with the residue 291 substituted with Phosphothreonine" [UniProtKB:Q9UBE8] comment: By similarity xref: UniProtKB:Q9UBE8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:B0068740 name: NLK_HUMAN-Phosphotyrosine293 def: "Protein NLK_HUMAN with the residue 293 substituted with Phosphotyrosine" [UniProtKB:Q9UBE8] comment: By similarity xref: UniProtKB:Q9UBE8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:B0068741 name: NLTP_HUMAN-N6-acetyllysine142 def: "Protein NLTP_HUMAN with the residue 142 substituted with N6-acetyllysine" [UniProtKB:P22307] comment: By similarity xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068742 name: NLTP_HUMAN-N6-acetyllysine173 def: "Protein NLTP_HUMAN with the residue 173 substituted with N6-acetyllysine" [UniProtKB:P22307] comment: By similarity xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068743 name: NLTP_HUMAN-Phosphotyrosine197 def: "Protein NLTP_HUMAN with the residue 197 substituted with Phosphotyrosine" [UniProtKB:P22307] xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068744 name: NLTP_HUMAN-Phosphotyrosine204 def: "Protein NLTP_HUMAN with the residue 204 substituted with Phosphotyrosine" [UniProtKB:P22307] xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068745 name: NLTP_HUMAN-N6-acetyllysine282 def: "Protein NLTP_HUMAN with the residue 282 substituted with N6-acetyllysine" [UniProtKB:P22307] comment: By similarity xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001636 ! sterol carrier activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005302 ! propanoyl-CoA C-acyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000359 ! peroxisome relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068746 name: NLTP_HUMAN-N6-acetyllysine341 def: "Protein NLTP_HUMAN with the residue 341 substituted with N6-acetyllysine" [UniProtKB:P22307] comment: By similarity xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068747 name: NLTP_HUMAN-Phosphoserine425 def: "Protein NLTP_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:P22307] comment: By similarity xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068748 name: NLTP_HUMAN-N6-acetyllysine453 def: "Protein NLTP_HUMAN with the residue 453 substituted with N6-acetyllysine" [UniProtKB:P22307] comment: By similarity xref: UniProtKB:P22307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:B0068749 name: NMB_HUMAN-Methionine amide56 def: "Protein NMB_HUMAN with the residue 56 substituted with Methionine amide" [UniProtKB:P08949] xref: UniProtKB:P08949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054938 ! NMB_HUMAN [Term] id: CCO:B0068750 name: NMDZ1_HUMAN-Phosphoserine889 def: "Protein NMDZ1_HUMAN with the residue 889 substituted with Phosphoserine" [UniProtKB:Q05586] comment: by PKC; Probable xref: UniProtKB:Q05586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055744 ! NMDZ1_HUMAN [Term] id: CCO:B0068751 name: NMDZ1_HUMAN-Phosphoserine890 def: "Protein NMDZ1_HUMAN with the residue 890 substituted with Phosphoserine" [UniProtKB:Q05586] comment: by PKC; Probable xref: UniProtKB:Q05586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001311 ! ionotropic glutamate receptor activity relationship: has_function CCO:F0001313 ! N-methyl-D-aspartate selective glutamate receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001508 ! extracellular-glutamate-gated ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0003209 ! glycine binding relationship: has_function CCO:F0003210 ! glutamate binding relationship: has_function CCO:F0005582 ! glutamate receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000740 ! postsynaptic density relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000845 ! N-methyl-D-aspartate selective glutamate receptor complex relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001005 ! dendrite relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0055744 ! NMDZ1_HUMAN [Term] id: CCO:B0068752 name: NMDZ1_HUMAN-Phosphoserine896 def: "Protein NMDZ1_HUMAN with the residue 896 substituted with Phosphoserine" [UniProtKB:Q05586] comment: by PKC; Probable xref: UniProtKB:Q05586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055744 ! NMDZ1_HUMAN [Term] id: CCO:B0068753 name: NMDZ1_HUMAN-Phosphoserine897 def: "Protein NMDZ1_HUMAN with the residue 897 substituted with Phosphoserine" [UniProtKB:Q05586] comment: by PKC; Probable xref: UniProtKB:Q05586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055744 ! NMDZ1_HUMAN [Term] id: CCO:B0068754 name: NMS_HUMAN-Asparagine amide141 def: "Protein NMS_HUMAN with the residue 141 substituted with Asparagine amide" [UniProtKB:Q5H8A3] comment: By similarity xref: UniProtKB:Q5H8A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000196 ! G-protein-coupled receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0056430 ! NMS_HUMAN [Term] id: CCO:B0068755 name: NMU_HUMAN-Asparagine amide166 def: "Protein NMU_HUMAN with the residue 166 substituted with Asparagine amide" [UniProtKB:P48645] comment: By similarity xref: UniProtKB:P48645 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055409 ! NMU_HUMAN [Term] id: CCO:B0068756 name: NO40_HUMAN-Phosphoserine114 def: "Protein NO40_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q9NP64] xref: UniProtKB:Q9NP64 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062848 ! NO40_HUMAN [Term] id: CCO:B0068757 name: NO66_HUMAN-Phosphoserine109 def: "Protein NO66_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q9H6W3] xref: UniProtKB:Q9H6W3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058736 ! NO66_HUMAN [Term] id: CCO:B0068758 name: NOG1_HUMAN-Phosphoserine558 def: "Protein NOG1_HUMAN with the residue 558 substituted with Phosphoserine" [UniProtKB:Q9BZE4] xref: UniProtKB:Q9BZE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002116 ! NOG1_HUMAN [Term] id: CCO:B0068759 name: NOG1_HUMAN-Phosphoserine578 def: "Protein NOG1_HUMAN with the residue 578 substituted with Phosphoserine" [UniProtKB:Q9BZE4] xref: UniProtKB:Q9BZE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002116 ! NOG1_HUMAN [Term] id: CCO:B0068760 name: NOL1_HUMAN-Phosphoserine36 def: "Protein NOL1_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0068761 name: NOL1_HUMAN-Phosphoserine666 def: "Protein NOL1_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0068762 name: NOL1_HUMAN-Phosphoserine675 def: "Protein NOL1_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0068763 name: NOL1_HUMAN-Phosphothreonine739 def: "Protein NOL1_HUMAN with the residue 739 substituted with Phosphothreonine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0068764 name: NOL1_HUMAN-Phosphothreonine776 def: "Protein NOL1_HUMAN with the residue 776 substituted with Phosphothreonine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0068765 name: NOL1_HUMAN-Phosphoserine786 def: "Protein NOL1_HUMAN with the residue 786 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0068766 name: NOL1_HUMAN-Phosphoserine812 def: "Protein NOL1_HUMAN with the residue 812 substituted with Phosphoserine" [UniProtKB:P46087] xref: UniProtKB:P46087 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001623 ! NOL1_HUMAN [Term] id: CCO:B0068767 name: NOL8_HUMAN-Phosphoserine296 def: "Protein NOL8_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068768 name: NOL8_HUMAN-Phosphoserine298 def: "Protein NOL8_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068769 name: NOL8_HUMAN-Phosphothreonine302 def: "Protein NOL8_HUMAN with the residue 302 substituted with Phosphothreonine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068770 name: NOL8_HUMAN-Phosphoserine304 def: "Protein NOL8_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068771 name: NOL8_HUMAN-Phosphoserine365 def: "Protein NOL8_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068772 name: NOL8_HUMAN-Phosphoserine378 def: "Protein NOL8_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068773 name: NOL8_HUMAN-Phosphothreonine381 def: "Protein NOL8_HUMAN with the residue 381 substituted with Phosphothreonine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068774 name: NOL8_HUMAN-Phosphoserine801 def: "Protein NOL8_HUMAN with the residue 801 substituted with Phosphoserine" [UniProtKB:Q76FK4] comment: By similarity xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068775 name: NOL8_HUMAN-Phosphoserine837 def: "Protein NOL8_HUMAN with the residue 837 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068776 name: NOL8_HUMAN-Phosphoserine838 def: "Protein NOL8_HUMAN with the residue 838 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068777 name: NOL8_HUMAN-Phosphoserine843 def: "Protein NOL8_HUMAN with the residue 843 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068778 name: NOL8_HUMAN-Phosphoserine845 def: "Protein NOL8_HUMAN with the residue 845 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068779 name: NOL8_HUMAN-Phosphothreonine888 def: "Protein NOL8_HUMAN with the residue 888 substituted with Phosphothreonine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068780 name: NOL8_HUMAN-Phosphoserine890 def: "Protein NOL8_HUMAN with the residue 890 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068781 name: NOL8_HUMAN-Phosphoserine1036 def: "Protein NOL8_HUMAN with the residue 1036 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068782 name: NOL8_HUMAN-Phosphoserine1082 def: "Protein NOL8_HUMAN with the residue 1082 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068783 name: NOL8_HUMAN-Phosphoserine1083 def: "Protein NOL8_HUMAN with the residue 1083 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068784 name: NOL8_HUMAN-Phosphoserine1084 def: "Protein NOL8_HUMAN with the residue 1084 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068785 name: NOL8_HUMAN-Phosphoserine1099 def: "Protein NOL8_HUMAN with the residue 1099 substituted with Phosphoserine" [UniProtKB:Q76FK4] xref: UniProtKB:Q76FK4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057103 ! NOL8_HUMAN [Term] id: CCO:B0068786 name: NOLC1_HUMAN-Phosphoserine366 def: "Protein NOLC1_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0068787 name: NOLC1_HUMAN-Phosphoserine580 def: "Protein NOLC1_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0068788 name: NOLC1_HUMAN-Phosphoserine582 def: "Protein NOLC1_HUMAN with the residue 582 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0068789 name: NOLC1_HUMAN-Phosphoserine622 def: "Protein NOLC1_HUMAN with the residue 622 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0068790 name: NOLC1_HUMAN-Phosphoserine686 def: "Protein NOLC1_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:Q14978] xref: UniProtKB:Q14978 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001793 ! NOLC1_HUMAN [Term] id: CCO:B0068791 name: NOS3_HUMAN-Phosphotyrosine81 def: "Protein NOS3_HUMAN with the residue 81 substituted with Phosphotyrosine" [UniProtKB:P29474] xref: UniProtKB:P29474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055215 ! NOS3_HUMAN [Term] id: CCO:B0068792 name: NOS3_HUMAN-Phosphothreonine495 def: "Protein NOS3_HUMAN with the residue 495 substituted with Phosphothreonine" [UniProtKB:P29474] comment: By similarity xref: UniProtKB:P29474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055215 ! NOS3_HUMAN [Term] id: CCO:B0068793 name: NOS3_HUMAN-Phosphoserine633 def: "Protein NOS3_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:P29474] comment: By similarity xref: UniProtKB:P29474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055215 ! NOS3_HUMAN [Term] id: CCO:B0068794 name: NOS3_HUMAN-Phosphothreonine1175 def: "Protein NOS3_HUMAN with the residue 1175 substituted with Phosphothreonine" [UniProtKB:P29474] comment: By similarity xref: UniProtKB:P29474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055215 ! NOS3_HUMAN [Term] id: CCO:B0068795 name: NOS3_HUMAN-Phosphoserine1177 def: "Protein NOS3_HUMAN with the residue 1177 substituted with Phosphoserine" [UniProtKB:P29474] comment: By similarity xref: UniProtKB:P29474 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055215 ! NOS3_HUMAN [Term] id: CCO:B0068796 name: NOSTN_HUMAN-Phosphothreonine174 def: "Protein NOSTN_HUMAN with the residue 174 substituted with Phosphothreonine" [UniProtKB:Q8IVI9] xref: UniProtKB:Q8IVI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0023770 ! NOSTN_HUMAN [Term] id: CCO:B0068797 name: NOSTN_HUMAN-Phosphoserine176 def: "Protein NOSTN_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q8IVI9] xref: UniProtKB:Q8IVI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023770 ! NOSTN_HUMAN [Term] id: CCO:B0068798 name: NOSTN_HUMAN-Phosphothreonine177 def: "Protein NOSTN_HUMAN with the residue 177 substituted with Phosphothreonine" [UniProtKB:Q8IVI9] xref: UniProtKB:Q8IVI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023770 ! NOSTN_HUMAN [Term] id: CCO:B0068799 name: NOTC2_HUMAN-Phosphothreonine1716 def: "Protein NOTC2_HUMAN with the residue 1716 substituted with Phosphothreonine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0068800 name: NOTC2_HUMAN-Phosphoserine1778 def: "Protein NOTC2_HUMAN with the residue 1778 substituted with Phosphoserine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0068801 name: NOTC2_HUMAN-Phosphothreonine1802 def: "Protein NOTC2_HUMAN with the residue 1802 substituted with Phosphothreonine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0068802 name: NOTC2_HUMAN-Phosphoserine1804 def: "Protein NOTC2_HUMAN with the residue 1804 substituted with Phosphoserine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0068803 name: NOTC2_HUMAN-Phosphothreonine2074 def: "Protein NOTC2_HUMAN with the residue 2074 substituted with Phosphothreonine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0068804 name: NOTC2_HUMAN-Phosphoserine2081 def: "Protein NOTC2_HUMAN with the residue 2081 substituted with Phosphoserine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0068805 name: NOTC2_HUMAN-Phosphothreonine2097 def: "Protein NOTC2_HUMAN with the residue 2097 substituted with Phosphothreonine" [UniProtKB:Q04721] xref: UniProtKB:Q04721 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001719 ! NOTC2_HUMAN [Term] id: CCO:B0068806 name: NOXA1_HUMAN-Phosphoserine172 def: "Protein NOXA1_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q86UR1] comment: by PKA; xref: UniProtKB:Q86UR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057254 ! NOXA1_HUMAN [Term] id: CCO:B0068807 name: NOXA1_HUMAN-Phosphoserine461 def: "Protein NOXA1_HUMAN with the residue 461 substituted with Phosphoserine" [UniProtKB:Q86UR1] comment: by PKA; xref: UniProtKB:Q86UR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057254 ! NOXA1_HUMAN [Term] id: CCO:B0068808 name: NP1L1_HUMAN-Phosphoserine69 def: "Protein NP1L1_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:P55209] xref: UniProtKB:P55209 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:B0068809 name: NP1L1_HUMAN-Phosphoserine143 def: "Protein NP1L1_HUMAN with the residue 143 substituted with Phosphoserine" [UniProtKB:P55209] xref: UniProtKB:P55209 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:B0068810 name: NPFF1_HUMAN-Phosphotyrosine216 def: "Protein NPFF1_HUMAN with the residue 216 substituted with Phosphotyrosine" [UniProtKB:Q9GZQ6] xref: UniProtKB:Q9GZQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058633 ! NPFF1_HUMAN [Term] id: CCO:B0068811 name: NPFF1_HUMAN-Phosphothreonine218 def: "Protein NPFF1_HUMAN with the residue 218 substituted with Phosphothreonine" [UniProtKB:Q9GZQ6] xref: UniProtKB:Q9GZQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058633 ! NPFF1_HUMAN [Term] id: CCO:B0068812 name: NPFF1_HUMAN-Phosphotyrosine225 def: "Protein NPFF1_HUMAN with the residue 225 substituted with Phosphotyrosine" [UniProtKB:Q9GZQ6] xref: UniProtKB:Q9GZQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058633 ! NPFF1_HUMAN [Term] id: CCO:B0068813 name: NPFF_HUMAN-Phenylalanine amide76 def: "Protein NPFF_HUMAN with the residue 76 substituted with Phenylalanine amide" [UniProtKB:O15130] comment: By similarity xref: UniProtKB:O15130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0054409 ! NPFF_HUMAN [Term] id: CCO:B0068814 name: NPFF_HUMAN-Phenylalanine amide110 def: "Protein NPFF_HUMAN with the residue 110 substituted with Phenylalanine amide" [UniProtKB:O15130] comment: By similarity xref: UniProtKB:O15130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054409 ! NPFF_HUMAN [Term] id: CCO:B0068815 name: NPHN_HUMAN-Phosphoserine432 def: "Protein NPHN_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:O60500] xref: UniProtKB:O60500 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0062983 ! NPHN_HUMAN [Term] id: CCO:B0068816 name: NPY_HUMAN-Tyrosine amide64 def: "Protein NPY_HUMAN with the residue 64 substituted with Tyrosine amide" [UniProtKB:P01303] xref: UniProtKB:P01303 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000196 ! G-protein-coupled receptor binding relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_function CCO:F0001514 ! calcium channel regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000243 ! cell relationship: transformation_of CCO:B0054851 ! NPY_HUMAN [Term] id: CCO:B0068817 name: NR1D1_HUMAN-Phosphoserine23 def: "Protein NR1D1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:P20393] xref: UniProtKB:P20393 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055121 ! NR1D1_HUMAN [Term] id: CCO:B0068818 name: NR2C2_HUMAN-Phosphoserine219 def: "Protein NR2C2_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:P49116] xref: UniProtKB:P49116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055416 ! NR2C2_HUMAN [Term] id: CCO:B0068819 name: NR2C2_HUMAN-Phosphothreonine224 def: "Protein NR2C2_HUMAN with the residue 224 substituted with Phosphothreonine" [UniProtKB:P49116] xref: UniProtKB:P49116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055416 ! NR2C2_HUMAN [Term] id: CCO:B0068820 name: NR2E1_HUMAN-Phosphoserine301 def: "Protein NR2E1_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:Q9Y466] xref: UniProtKB:Q9Y466 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002433 ! pseudouridine synthase activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059350 ! NR2E1_HUMAN [Term] id: CCO:B0068821 name: NR2E3_HUMAN-Phosphothreonine333 def: "Protein NR2E3_HUMAN with the residue 333 substituted with Phosphothreonine" [UniProtKB:Q9Y5X4] xref: UniProtKB:Q9Y5X4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059391 ! NR2E3_HUMAN [Term] id: CCO:B0068822 name: NR4A1_HUMAN-Phosphoserine341 def: "Protein NR4A1_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:P22736] comment: by PKA; By similarity xref: UniProtKB:P22736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055150 ! NR4A1_HUMAN [Term] id: CCO:B0068823 name: NR4A1_HUMAN-Phosphoserine351 def: "Protein NR4A1_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:P22736] comment: by PKA; By similarity xref: UniProtKB:P22736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055150 ! NR4A1_HUMAN [Term] id: CCO:B0068824 name: NR4A2_HUMAN-Phosphoserine181 def: "Protein NR4A2_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:P43354] xref: UniProtKB:P43354 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055363 ! NR4A2_HUMAN [Term] id: CCO:B0068825 name: NRBF2_HUMAN-Phosphoserine120 def: "Protein NRBF2_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:Q96F24] xref: UniProtKB:Q96F24 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058209 ! NRBF2_HUMAN [Term] id: CCO:B0068826 name: NRBP_HUMAN-Phosphothreonine431 def: "Protein NRBP_HUMAN with the residue 431 substituted with Phosphothreonine" [UniProtKB:Q9UHY1] xref: UniProtKB:Q9UHY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062919 ! NRBP_HUMAN [Term] id: CCO:B0068827 name: NRBP_HUMAN-Phosphothreonine433 def: "Protein NRBP_HUMAN with the residue 433 substituted with Phosphothreonine" [UniProtKB:Q9UHY1] xref: UniProtKB:Q9UHY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062919 ! NRBP_HUMAN [Term] id: CCO:B0068828 name: NRBP_HUMAN-Phosphothreonine441 def: "Protein NRBP_HUMAN with the residue 441 substituted with Phosphothreonine" [UniProtKB:Q9UHY1] comment: By similarity xref: UniProtKB:Q9UHY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0062919 ! NRBP_HUMAN [Term] id: CCO:B0068829 name: NRF1_HUMAN-Phosphoserine39 def: "Protein NRF1_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q16656] comment: by CK2; xref: UniProtKB:Q16656 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056169 ! NRF1_HUMAN [Term] id: CCO:B0068830 name: NRF1_HUMAN-Phosphoserine44 def: "Protein NRF1_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q16656] comment: by CK2; xref: UniProtKB:Q16656 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056169 ! NRF1_HUMAN [Term] id: CCO:B0068831 name: NRF1_HUMAN-Phosphoserine46 def: "Protein NRF1_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:Q16656] comment: by CK2; xref: UniProtKB:Q16656 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056169 ! NRF1_HUMAN [Term] id: CCO:B0068832 name: NRF1_HUMAN-Phosphoserine47 def: "Protein NRF1_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q16656] comment: by CK2; xref: UniProtKB:Q16656 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056169 ! NRF1_HUMAN [Term] id: CCO:B0068833 name: NRF1_HUMAN-Phosphoserine52 def: "Protein NRF1_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q16656] comment: by CK2; xref: UniProtKB:Q16656 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056169 ! NRF1_HUMAN [Term] id: CCO:B0068834 name: NRG2_HUMAN-Phosphoserine809 def: "Protein NRG2_HUMAN with the residue 809 substituted with Phosphoserine" [UniProtKB:O14511] comment: By similarity xref: UniProtKB:O14511 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054346 ! NRG2_HUMAN [Term] id: CCO:B0068835 name: NRG3_HUMAN-Phosphoserine116 def: "Protein NRG3_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:P56975] xref: UniProtKB:P56975 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055554 ! NRG3_HUMAN [Term] id: CCO:B0068836 name: NRG3_HUMAN-Phosphoserine119 def: "Protein NRG3_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:P56975] xref: UniProtKB:P56975 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001702 ! growth factor activity relationship: has_function CCO:F0004384 ! transmembrane receptor protein tyrosine kinase activator activity relationship: has_function CCO:F0004611 ! receptor tyrosine kinase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055554 ! NRG3_HUMAN [Term] id: CCO:B0068837 name: NRIP1_HUMAN-Phosphoserine104 def: "Protein NRIP1_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_function CCO:F0005585 ! nuclear hormone receptor binding relationship: has_function CCO:F0005587 ! glucocorticoid receptor binding relationship: has_function CCO:F0005720 ! histone deacetylase binding relationship: has_function CCO:F0006286 ! retinoid X receptor binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068838 name: NRIP1_HUMAN-N6-acetyllysine111 def: "Protein NRIP1_HUMAN with the residue 111 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068839 name: NRIP1_HUMAN-N6-acetyllysine158 def: "Protein NRIP1_HUMAN with the residue 158 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068840 name: NRIP1_HUMAN-Phosphothreonine207 def: "Protein NRIP1_HUMAN with the residue 207 substituted with Phosphothreonine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068841 name: NRIP1_HUMAN-N6-acetyllysine286 def: "Protein NRIP1_HUMAN with the residue 286 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068842 name: NRIP1_HUMAN-N6-acetyllysine310 def: "Protein NRIP1_HUMAN with the residue 310 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068843 name: NRIP1_HUMAN-Phosphoserine356 def: "Protein NRIP1_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068844 name: NRIP1_HUMAN-Phosphoserine378 def: "Protein NRIP1_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068845 name: NRIP1_HUMAN-N6-acetyllysine446 def: "Protein NRIP1_HUMAN with the residue 446 substituted with N6-acetyllysine" [UniProtKB:P48552] xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068846 name: NRIP1_HUMAN-N6-acetyllysine481 def: "Protein NRIP1_HUMAN with the residue 481 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068847 name: NRIP1_HUMAN-Phosphoserine487 def: "Protein NRIP1_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068848 name: NRIP1_HUMAN-Phosphoserine518 def: "Protein NRIP1_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068849 name: NRIP1_HUMAN-N6-acetyllysine528 def: "Protein NRIP1_HUMAN with the residue 528 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068850 name: NRIP1_HUMAN-Phosphoserine542 def: "Protein NRIP1_HUMAN with the residue 542 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068851 name: NRIP1_HUMAN-N6-acetyllysine606 def: "Protein NRIP1_HUMAN with the residue 606 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068852 name: NRIP1_HUMAN-Phosphoserine671 def: "Protein NRIP1_HUMAN with the residue 671 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068853 name: NRIP1_HUMAN-Phosphothreonine731 def: "Protein NRIP1_HUMAN with the residue 731 substituted with Phosphothreonine" [UniProtKB:P48552] xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068854 name: NRIP1_HUMAN-N6-acetyllysine931 def: "Protein NRIP1_HUMAN with the residue 931 substituted with N6-acetyllysine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068855 name: NRIP1_HUMAN-Phosphoserine1001 def: "Protein NRIP1_HUMAN with the residue 1001 substituted with Phosphoserine" [UniProtKB:P48552] comment: By similarity xref: UniProtKB:P48552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:B0068856 name: NRP1_HUMAN-Phosphotyrosine920 def: "Protein NRP1_HUMAN with the residue 920 substituted with Phosphotyrosine" [UniProtKB:O14786] xref: UniProtKB:O14786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005447 ! NRP1_HUMAN [Term] id: CCO:B0068857 name: NSBP1_HUMAN-Phosphoserine20 def: "Protein NSBP1_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P82970] xref: UniProtKB:P82970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055657 ! NSBP1_HUMAN [Term] id: CCO:B0068858 name: NSBP1_HUMAN-Phosphoserine24 def: "Protein NSBP1_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:P82970] xref: UniProtKB:P82970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055657 ! NSBP1_HUMAN [Term] id: CCO:B0068859 name: NSBP1_HUMAN-Phosphothreonine31 def: "Protein NSBP1_HUMAN with the residue 31 substituted with Phosphothreonine" [UniProtKB:P82970] xref: UniProtKB:P82970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055657 ! NSBP1_HUMAN [Term] id: CCO:B0068860 name: NSBP1_HUMAN-Phosphotyrosine76 def: "Protein NSBP1_HUMAN with the residue 76 substituted with Phosphotyrosine" [UniProtKB:P82970] xref: UniProtKB:P82970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055657 ! NSBP1_HUMAN [Term] id: CCO:B0068861 name: NSD1_HUMAN-Phosphoserine766 def: "Protein NSD1_HUMAN with the residue 766 substituted with Phosphoserine" [UniProtKB:Q96L73] xref: UniProtKB:Q96L73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058266 ! NSD1_HUMAN [Term] id: CCO:B0068862 name: NSD1_HUMAN-Phosphoserine2471 def: "Protein NSD1_HUMAN with the residue 2471 substituted with Phosphoserine" [UniProtKB:Q96L73] xref: UniProtKB:Q96L73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003472 ! ligand-dependent nuclear receptor binding relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_function CCO:F0005710 ! histone lysine N-methyltransferase activity (H4-K20 specific) relationship: has_function CCO:F0005774 ! retinoic acid receptor binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006286 ! retinoid X receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_function CCO:F0006292 ! histone lysine N-methyltransferase activity (H3-K36 specific) relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058266 ! NSD1_HUMAN [Term] id: CCO:B0068863 name: NSD2_HUMAN-Phosphoserine102 def: "Protein NSD2_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:O96028] xref: UniProtKB:O96028 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054823 ! NSD2_HUMAN [Term] id: CCO:B0068864 name: NSD2_HUMAN-Phosphothreonine544 def: "Protein NSD2_HUMAN with the residue 544 substituted with Phosphothreonine" [UniProtKB:O96028] xref: UniProtKB:O96028 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054823 ! NSD2_HUMAN [Term] id: CCO:B0068865 name: NSF1C_HUMAN-Phosphoserine74 def: "Protein NSF1C_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q9UNZ2] comment: By similarity xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:B0068866 name: NSF1C_HUMAN-Phosphoserine114 def: "Protein NSF1C_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q9UNZ2] xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:B0068867 name: NSF1C_HUMAN-Phosphoserine140 def: "Protein NSF1C_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q9UNZ2] xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:B0068868 name: NSF1C_HUMAN-Phosphoserine165 def: "Protein NSF1C_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q9UNZ2] xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:B0068869 name: NSF1C_HUMAN-Phosphotyrosine167 def: "Protein NSF1C_HUMAN with the residue 167 substituted with Phosphotyrosine" [UniProtKB:Q9UNZ2] xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:B0068870 name: NSF1C_HUMAN-Phosphoserine176 def: "Protein NSF1C_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q9UNZ2] comment: By similarity xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:B0068871 name: NSF1C_HUMAN-Phosphoserine272 def: "Protein NSF1C_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q9UNZ2] xref: UniProtKB:Q9UNZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:B0068872 name: NTAL_HUMAN-Phosphotyrosine58 def: "Protein NTAL_HUMAN with the residue 58 substituted with Phosphotyrosine" [UniProtKB:Q9GZY6] comment: By similarity xref: UniProtKB:Q9GZY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058644 ! NTAL_HUMAN [Term] id: CCO:B0068873 name: NTAL_HUMAN-Phosphoserine59 def: "Protein NTAL_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:Q9GZY6] comment: By similarity xref: UniProtKB:Q9GZY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058644 ! NTAL_HUMAN [Term] id: CCO:B0068874 name: NTAL_HUMAN-Phosphotyrosine136 def: "Protein NTAL_HUMAN with the residue 136 substituted with Phosphotyrosine" [UniProtKB:Q9GZY6] comment: Probable xref: UniProtKB:Q9GZY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058644 ! NTAL_HUMAN [Term] id: CCO:B0068875 name: NTAL_HUMAN-Phosphotyrosine193 def: "Protein NTAL_HUMAN with the residue 193 substituted with Phosphotyrosine" [UniProtKB:Q9GZY6] comment: Probable xref: UniProtKB:Q9GZY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058644 ! NTAL_HUMAN [Term] id: CCO:B0068876 name: NTAL_HUMAN-Phosphotyrosine233 def: "Protein NTAL_HUMAN with the residue 233 substituted with Phosphotyrosine" [UniProtKB:Q9GZY6] xref: UniProtKB:Q9GZY6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0058644 ! NTAL_HUMAN [Term] id: CCO:B0068877 name: NTRK1_HUMAN-Phosphotyrosine496 def: "Protein NTRK1_HUMAN with the residue 496 substituted with Phosphotyrosine" [UniProtKB:P04629] comment: by autocatalysis; xref: UniProtKB:P04629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054892 ! NTRK1_HUMAN [Term] id: CCO:B0068878 name: NTRK1_HUMAN-Phosphotyrosine676 def: "Protein NTRK1_HUMAN with the residue 676 substituted with Phosphotyrosine" [UniProtKB:P04629] comment: by autocatalysis; xref: UniProtKB:P04629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054892 ! NTRK1_HUMAN [Term] id: CCO:B0068879 name: NTRK1_HUMAN-Phosphotyrosine680 def: "Protein NTRK1_HUMAN with the residue 680 substituted with Phosphotyrosine" [UniProtKB:P04629] comment: by autocatalysis; xref: UniProtKB:P04629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005795 ! neurotrophin binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054892 ! NTRK1_HUMAN [Term] id: CCO:B0068880 name: NTRK1_HUMAN-Phosphotyrosine681 def: "Protein NTRK1_HUMAN with the residue 681 substituted with Phosphotyrosine" [UniProtKB:P04629] comment: by autocatalysis; xref: UniProtKB:P04629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054892 ! NTRK1_HUMAN [Term] id: CCO:B0068881 name: NTRK1_HUMAN-Phosphotyrosine791 def: "Protein NTRK1_HUMAN with the residue 791 substituted with Phosphotyrosine" [UniProtKB:P04629] comment: by autocatalysis; xref: UniProtKB:P04629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054892 ! NTRK1_HUMAN [Term] id: CCO:B0068882 name: NTRK2_HUMAN-Phosphotyrosine516 def: "Protein NTRK2_HUMAN with the residue 516 substituted with Phosphotyrosine" [UniProtKB:Q16620] comment: by autocatalysis; By similarity xref: UniProtKB:Q16620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056161 ! NTRK2_HUMAN [Term] id: CCO:B0068883 name: NTRK2_HUMAN-Phosphotyrosine702 def: "Protein NTRK2_HUMAN with the residue 702 substituted with Phosphotyrosine" [UniProtKB:Q16620] comment: by autocatalysis; By similarity xref: UniProtKB:Q16620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056161 ! NTRK2_HUMAN [Term] id: CCO:B0068884 name: NTRK2_HUMAN-Phosphotyrosine706 def: "Protein NTRK2_HUMAN with the residue 706 substituted with Phosphotyrosine" [UniProtKB:Q16620] comment: by autocatalysis; By similarity xref: UniProtKB:Q16620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005795 ! neurotrophin binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056161 ! NTRK2_HUMAN [Term] id: CCO:B0068885 name: NTRK2_HUMAN-Phosphotyrosine707 def: "Protein NTRK2_HUMAN with the residue 707 substituted with Phosphotyrosine" [UniProtKB:Q16620] comment: by autocatalysis; By similarity xref: UniProtKB:Q16620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056161 ! NTRK2_HUMAN [Term] id: CCO:B0068886 name: NTRK2_HUMAN-Phosphotyrosine817 def: "Protein NTRK2_HUMAN with the residue 817 substituted with Phosphotyrosine" [UniProtKB:Q16620] comment: by autocatalysis; By similarity xref: UniProtKB:Q16620 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056161 ! NTRK2_HUMAN [Term] id: CCO:B0068887 name: NTRK3_HUMAN-Phosphotyrosine516 def: "Protein NTRK3_HUMAN with the residue 516 substituted with Phosphotyrosine" [UniProtKB:Q16288] comment: by autocatalysis; By similarity xref: UniProtKB:Q16288 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056133 ! NTRK3_HUMAN [Term] id: CCO:B0068888 name: NTRK3_HUMAN-Phosphotyrosine705 def: "Protein NTRK3_HUMAN with the residue 705 substituted with Phosphotyrosine" [UniProtKB:Q16288] comment: by autocatalysis; By similarity xref: UniProtKB:Q16288 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005795 ! neurotrophin binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056133 ! NTRK3_HUMAN [Term] id: CCO:B0068889 name: NTRK3_HUMAN-Phosphotyrosine709 def: "Protein NTRK3_HUMAN with the residue 709 substituted with Phosphotyrosine" [UniProtKB:Q16288] comment: by autocatalysis; By similarity xref: UniProtKB:Q16288 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056133 ! NTRK3_HUMAN [Term] id: CCO:B0068890 name: NTRK3_HUMAN-Phosphotyrosine710 def: "Protein NTRK3_HUMAN with the residue 710 substituted with Phosphotyrosine" [UniProtKB:Q16288] comment: by autocatalysis; By similarity xref: UniProtKB:Q16288 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056133 ! NTRK3_HUMAN [Term] id: CCO:B0068891 name: NTRK3_HUMAN-Phosphotyrosine834 def: "Protein NTRK3_HUMAN with the residue 834 substituted with Phosphotyrosine" [UniProtKB:Q16288] comment: By similarity xref: UniProtKB:Q16288 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056133 ! NTRK3_HUMAN [Term] id: CCO:B0068892 name: NU107_HUMAN-Phosphoserine4 def: "Protein NU107_HUMAN with the residue 4 substituted with Phosphoserine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068893 name: NU107_HUMAN-Phosphoserine11 def: "Protein NU107_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068894 name: NU107_HUMAN-Phosphoserine37 def: "Protein NU107_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068895 name: NU107_HUMAN-Phosphothreonine46 def: "Protein NU107_HUMAN with the residue 46 substituted with Phosphothreonine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068896 name: NU107_HUMAN-Phosphothreonine55 def: "Protein NU107_HUMAN with the residue 55 substituted with Phosphothreonine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068897 name: NU107_HUMAN-Phosphoserine58 def: "Protein NU107_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068898 name: NU107_HUMAN-Phosphothreonine64 def: "Protein NU107_HUMAN with the residue 64 substituted with Phosphothreonine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001632 ! nucleocytoplasmic transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000260 ! nuclear pore relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068899 name: NU107_HUMAN-Phosphoserine69 def: "Protein NU107_HUMAN with the residue 69 substituted with Phosphoserine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068900 name: NU107_HUMAN-Phosphoserine77 def: "Protein NU107_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068901 name: NU107_HUMAN-Phosphoserine86 def: "Protein NU107_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:P57740] xref: UniProtKB:P57740 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:B0068902 name: NU133_HUMAN-Phosphoserine27 def: "Protein NU133_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q8WUM0] xref: UniProtKB:Q8WUM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063021 ! NU133_HUMAN [Term] id: CCO:B0068903 name: NU133_HUMAN-Phosphothreonine28 def: "Protein NU133_HUMAN with the residue 28 substituted with Phosphothreonine" [UniProtKB:Q8WUM0] xref: UniProtKB:Q8WUM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063021 ! NU133_HUMAN [Term] id: CCO:B0068904 name: NU133_HUMAN-Phosphoserine41 def: "Protein NU133_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q8WUM0] xref: UniProtKB:Q8WUM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063021 ! NU133_HUMAN [Term] id: CCO:B0068905 name: NU133_HUMAN-Phosphoserine45 def: "Protein NU133_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q8WUM0] xref: UniProtKB:Q8WUM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063021 ! NU133_HUMAN [Term] id: CCO:B0068906 name: NU133_HUMAN-Phosphoserine50 def: "Protein NU133_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:Q8WUM0] xref: UniProtKB:Q8WUM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063021 ! NU133_HUMAN [Term] id: CCO:B0068907 name: NU133_HUMAN-Phosphoserine501 def: "Protein NU133_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q8WUM0] comment: By similarity xref: UniProtKB:Q8WUM0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001632 ! nucleocytoplasmic transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000104 ! condensed chromosome kinetochore relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000260 ! nuclear pore relationship: transformation_of CCO:B0063021 ! NU133_HUMAN [Term] id: CCO:B0068908 name: NUDT5_HUMAN-Phosphoserine9 def: "Protein NUDT5_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:Q9UKK9] comment: By similarity xref: UniProtKB:Q9UKK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063479 ! NUDT5_HUMAN [Term] id: CCO:B0068909 name: NUDT5_HUMAN-Phosphotyrosine74 def: "Protein NUDT5_HUMAN with the residue 74 substituted with Phosphotyrosine" [UniProtKB:Q9UKK9] xref: UniProtKB:Q9UKK9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063479 ! NUDT5_HUMAN [Term] id: CCO:B0068910 name: NUFP1_HUMAN-Phosphoserine133 def: "Protein NUFP1_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:Q9UHK0] xref: UniProtKB:Q9UHK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:B0068911 name: NUFP1_HUMAN-Phosphoserine338 def: "Protein NUFP1_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:Q9UHK0] xref: UniProtKB:Q9UHK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:B0068912 name: NUFP1_HUMAN-Phosphoserine340 def: "Protein NUFP1_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q9UHK0] xref: UniProtKB:Q9UHK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:B0068913 name: NUFP1_HUMAN-Phosphoserine342 def: "Protein NUFP1_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:Q9UHK0] xref: UniProtKB:Q9UHK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:B0068914 name: NUFP1_HUMAN-Phosphotyrosine476 def: "Protein NUFP1_HUMAN with the residue 476 substituted with Phosphotyrosine" [UniProtKB:Q9UHK0] xref: UniProtKB:Q9UHK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:B0068915 name: NUFP1_HUMAN-Phosphothreonine487 def: "Protein NUFP1_HUMAN with the residue 487 substituted with Phosphothreonine" [UniProtKB:Q9UHK0] xref: UniProtKB:Q9UHK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:B0068916 name: NUFP1_HUMAN-Phosphoserine489 def: "Protein NUFP1_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q9UHK0] xref: UniProtKB:Q9UHK0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:B0068917 name: NUMA1_HUMAN-Phosphoserine198 def: "Protein NUMA1_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068918 name: NUMA1_HUMAN-Phosphoserine1788 def: "Protein NUMA1_HUMAN with the residue 1788 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068919 name: NUMA1_HUMAN-Phosphoserine1789 def: "Protein NUMA1_HUMAN with the residue 1789 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068920 name: NUMA1_HUMAN-Phosphoserine1792 def: "Protein NUMA1_HUMAN with the residue 1792 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068921 name: NUMA1_HUMAN-Phosphoserine1800 def: "Protein NUMA1_HUMAN with the residue 1800 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068922 name: NUMA1_HUMAN-Phosphothreonine1804 def: "Protein NUMA1_HUMAN with the residue 1804 substituted with Phosphothreonine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068923 name: NUMA1_HUMAN-Phosphotyrosine1836 def: "Protein NUMA1_HUMAN with the residue 1836 substituted with Phosphotyrosine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068924 name: NUMA1_HUMAN-Phosphoserine1837 def: "Protein NUMA1_HUMAN with the residue 1837 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068925 name: NUMA1_HUMAN-Phosphoserine1887 def: "Protein NUMA1_HUMAN with the residue 1887 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068926 name: NUMA1_HUMAN-Phosphoserine1991 def: "Protein NUMA1_HUMAN with the residue 1991 substituted with Phosphoserine" [UniProtKB:Q14980] xref: UniProtKB:Q14980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:B0068927 name: NUMBL_HUMAN-Phosphoserine263 def: "Protein NUMBL_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q9Y6R0] xref: UniProtKB:Q9Y6R0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059414 ! NUMBL_HUMAN [Term] id: CCO:B0068928 name: NUMBL_HUMAN-Phosphothreonine268 def: "Protein NUMBL_HUMAN with the residue 268 substituted with Phosphothreonine" [UniProtKB:Q9Y6R0] xref: UniProtKB:Q9Y6R0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059414 ! NUMBL_HUMAN [Term] id: CCO:B0068929 name: NUMBL_HUMAN-Phosphothreonine279 def: "Protein NUMBL_HUMAN with the residue 279 substituted with Phosphothreonine" [UniProtKB:Q9Y6R0] xref: UniProtKB:Q9Y6R0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059414 ! NUMBL_HUMAN [Term] id: CCO:B0068930 name: NUMBL_HUMAN-Phosphoserine411 def: "Protein NUMBL_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q9Y6R0] xref: UniProtKB:Q9Y6R0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059414 ! NUMBL_HUMAN [Term] id: CCO:B0068931 name: NUP98_HUMAN-Phosphoserine608 def: "Protein NUP98_HUMAN with the residue 608 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068932 name: NUP98_HUMAN-Phosphoserine612 def: "Protein NUP98_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068933 name: NUP98_HUMAN-Phosphoserine623 def: "Protein NUP98_HUMAN with the residue 623 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068934 name: NUP98_HUMAN-Phosphoserine839 def: "Protein NUP98_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068935 name: NUP98_HUMAN-Phosphoserine888 def: "Protein NUP98_HUMAN with the residue 888 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068936 name: NUP98_HUMAN-Phosphoserine934 def: "Protein NUP98_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068937 name: NUP98_HUMAN-Phosphothreonine1000 def: "Protein NUP98_HUMAN with the residue 1000 substituted with Phosphothreonine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068938 name: NUP98_HUMAN-Phosphoserine1023 def: "Protein NUP98_HUMAN with the residue 1023 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068939 name: NUP98_HUMAN-Phosphoserine1028 def: "Protein NUP98_HUMAN with the residue 1028 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068940 name: NUP98_HUMAN-Phosphoserine1043 def: "Protein NUP98_HUMAN with the residue 1043 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068941 name: NUP98_HUMAN-Phosphoserine1060 def: "Protein NUP98_HUMAN with the residue 1060 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003535 ! structural constituent of nuclear pore relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001358 ! nuclear membrane relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068942 name: NUP98_HUMAN-Phosphoserine1064 def: "Protein NUP98_HUMAN with the residue 1064 substituted with Phosphoserine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068943 name: NUP98_HUMAN-Phosphothreonine1070 def: "Protein NUP98_HUMAN with the residue 1070 substituted with Phosphothreonine" [UniProtKB:P52948] xref: UniProtKB:P52948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055505 ! NUP98_HUMAN [Term] id: CCO:B0068944 name: NUPL_HUMAN-Phosphothreonine177 def: "Protein NUPL_HUMAN with the residue 177 substituted with Phosphothreonine" [UniProtKB:P52594] xref: UniProtKB:P52594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055487 ! NUPL_HUMAN [Term] id: CCO:B0068945 name: NUPL_HUMAN-Phosphoserine179 def: "Protein NUPL_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:P52594] comment: By similarity xref: UniProtKB:P52594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055487 ! NUPL_HUMAN [Term] id: CCO:B0068946 name: NUPL_HUMAN-Phosphoserine181 def: "Protein NUPL_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:P52594] xref: UniProtKB:P52594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055487 ! NUPL_HUMAN [Term] id: CCO:B0068947 name: NUSAP_HUMAN-Phosphothreonine182 def: "Protein NUSAP_HUMAN with the residue 182 substituted with Phosphothreonine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0068948 name: NUSAP_HUMAN-Phosphothreonine349 def: "Protein NUSAP_HUMAN with the residue 349 substituted with Phosphothreonine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0068949 name: NUSAP_HUMAN-Phosphoserine352 def: "Protein NUSAP_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q9BXS6] xref: UniProtKB:Q9BXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002108 ! NUSAP_HUMAN [Term] id: CCO:B0068950 name: O52E8_HUMAN-Phosphoserine140 def: "Protein O52E8_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q6IFG1] xref: UniProtKB:Q6IFG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056789 ! O52E8_HUMAN [Term] id: CCO:B0068951 name: O52E8_HUMAN-Phosphoserine144 def: "Protein O52E8_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q6IFG1] xref: UniProtKB:Q6IFG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056789 ! O52E8_HUMAN [Term] id: CCO:B0068952 name: O56A3_HUMAN-Phosphotyrosine172 def: "Protein O56A3_HUMAN with the residue 172 substituted with Phosphotyrosine" [UniProtKB:Q8NH54] xref: UniProtKB:Q8NH54 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057829 ! O56A3_HUMAN [Term] id: CCO:B0068953 name: ODBA_HUMAN-Phosphoserine337 def: "Protein ODBA_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:P12694] xref: UniProtKB:P12694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000345 ! alpha-ketoacid dehydrogenase activity relationship: has_function CCO:F0000382 ! 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003203 ! cyclin-dependent protein kinase 5 activator regulator activity relationship: has_function CCO:F0003226 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor relationship: has_function CCO:F0003398 ! carboxy-lyase activity relationship: has_function CCO:F0004609 ! potassium ion binding relationship: has_function CCO:F0004983 ! protein complex binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000342 ! mitochondrial matrix relationship: located_in CCO:C0000497 ! mitochondrial alpha-ketoglutarate dehydrogenase complex relationship: transformation_of CCO:B0055003 ! ODBA_HUMAN [Term] id: CCO:B0068954 name: ODBA_HUMAN-Phosphotyrosine345 def: "Protein ODBA_HUMAN with the residue 345 substituted with Phosphotyrosine" [UniProtKB:P12694] xref: UniProtKB:P12694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055003 ! ODBA_HUMAN [Term] id: CCO:B0068955 name: ODBA_HUMAN-Phosphoserine347 def: "Protein ODBA_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:P12694] xref: UniProtKB:P12694 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055003 ! ODBA_HUMAN [Term] id: CCO:B0068956 name: ODPA_HUMAN-Phosphoserine232 def: "Protein ODPA_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:P08559] xref: UniProtKB:P08559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025860 ! ODPA_HUMAN [Term] id: CCO:B0068957 name: ODPA_HUMAN-Phosphotyrosine289 def: "Protein ODPA_HUMAN with the residue 289 substituted with Phosphotyrosine" [UniProtKB:P08559] xref: UniProtKB:P08559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025860 ! ODPA_HUMAN [Term] id: CCO:B0068958 name: ODPA_HUMAN-Phosphoserine293 def: "Protein ODPA_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:P08559] xref: UniProtKB:P08559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025860 ! ODPA_HUMAN [Term] id: CCO:B0068959 name: ODPA_HUMAN-Phosphoserine295 def: "Protein ODPA_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:P08559] xref: UniProtKB:P08559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025860 ! ODPA_HUMAN [Term] id: CCO:B0068960 name: ODPA_HUMAN-Phosphoserine300 def: "Protein ODPA_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:P08559] xref: UniProtKB:P08559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025860 ! ODPA_HUMAN [Term] id: CCO:B0068961 name: ODPA_HUMAN-Phosphotyrosine301 def: "Protein ODPA_HUMAN with the residue 301 substituted with Phosphotyrosine" [UniProtKB:P08559] xref: UniProtKB:P08559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025860 ! ODPA_HUMAN [Term] id: CCO:B0068962 name: OGFR_HUMAN-Phosphoserine315 def: "Protein OGFR_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q9NZT2] xref: UniProtKB:Q9NZT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059017 ! OGFR_HUMAN [Term] id: CCO:B0068963 name: OGFR_HUMAN-Phosphoserine349 def: "Protein OGFR_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q9NZT2] xref: UniProtKB:Q9NZT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059017 ! OGFR_HUMAN [Term] id: CCO:B0068964 name: OGFR_HUMAN-Phosphoserine361 def: "Protein OGFR_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9NZT2] xref: UniProtKB:Q9NZT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059017 ! OGFR_HUMAN [Term] id: CCO:B0068965 name: OGFR_HUMAN-Phosphoserine378 def: "Protein OGFR_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:Q9NZT2] xref: UniProtKB:Q9NZT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059017 ! OGFR_HUMAN [Term] id: CCO:B0068966 name: OGFR_HUMAN-Phosphoserine420 def: "Protein OGFR_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:Q9NZT2] xref: UniProtKB:Q9NZT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059017 ! OGFR_HUMAN [Term] id: CCO:B0068967 name: OGFR_HUMAN-Phosphoserine484 def: "Protein OGFR_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:Q9NZT2] xref: UniProtKB:Q9NZT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001323 ! opioid receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059017 ! OGFR_HUMAN [Term] id: CCO:B0068968 name: OMP_HUMAN-N-acetylalanine2 def: "Protein OMP_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P47874] comment: By similarity xref: UniProtKB:P47874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055387 ! OMP_HUMAN [Term] id: CCO:B0068969 name: OPA1_HUMAN-Phosphoserine21 def: "Protein OPA1_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:O60313] xref: UniProtKB:O60313 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054545 ! OPA1_HUMAN [Term] id: CCO:B0068970 name: OPA1_HUMAN-Phosphoserine22 def: "Protein OPA1_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:O60313] xref: UniProtKB:O60313 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054545 ! OPA1_HUMAN [Term] id: CCO:B0068971 name: OPA1_HUMAN-Phosphothreonine652 def: "Protein OPA1_HUMAN with the residue 652 substituted with Phosphothreonine" [UniProtKB:O60313] comment: By similarity xref: UniProtKB:O60313 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054545 ! OPA1_HUMAN [Term] id: CCO:B0068972 name: OPSD_HUMAN-N-acetylmethionine1 def: "Protein OPSD_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P08100] comment: By similarity xref: UniProtKB:P08100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054919 ! OPSD_HUMAN [Term] id: CCO:B0068973 name: OPSD_HUMAN-Phosphoserine334 def: "Protein OPSD_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:P08100] comment: By similarity xref: UniProtKB:P08100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054919 ! OPSD_HUMAN [Term] id: CCO:B0068974 name: OPSD_HUMAN-Phosphoserine338 def: "Protein OPSD_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:P08100] comment: By similarity xref: UniProtKB:P08100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054919 ! OPSD_HUMAN [Term] id: CCO:B0068975 name: OPSD_HUMAN-Phosphoserine343 def: "Protein OPSD_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:P08100] comment: By similarity xref: UniProtKB:P08100 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002410 ! photoreceptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000185 ! photoreceptor outer segment relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054919 ! OPSD_HUMAN [Term] id: CCO:B0068976 name: OPTN_HUMAN-Phosphoserine170 def: "Protein OPTN_HUMAN with the residue 170 substituted with Phosphoserine" [UniProtKB:Q96CV9] xref: UniProtKB:Q96CV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030838 ! OPTN_HUMAN [Term] id: CCO:B0068977 name: OPTN_HUMAN-Phosphoserine171 def: "Protein OPTN_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q96CV9] xref: UniProtKB:Q96CV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030838 ! OPTN_HUMAN [Term] id: CCO:B0068978 name: OPTN_HUMAN-Phosphoserine173 def: "Protein OPTN_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q96CV9] xref: UniProtKB:Q96CV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030838 ! OPTN_HUMAN [Term] id: CCO:B0068979 name: OPTN_HUMAN-Phosphoserine174 def: "Protein OPTN_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:Q96CV9] xref: UniProtKB:Q96CV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030838 ! OPTN_HUMAN [Term] id: CCO:B0068980 name: OPTN_HUMAN-Phosphoserine177 def: "Protein OPTN_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:Q96CV9] comment: By similarity xref: UniProtKB:Q96CV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0030838 ! OPTN_HUMAN [Term] id: CCO:B0068981 name: OR1C1_HUMAN-Phosphothreonine7 def: "Protein OR1C1_HUMAN with the residue 7 substituted with Phosphothreonine" [UniProtKB:Q15619] xref: UniProtKB:Q15619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056080 ! OR1C1_HUMAN [Term] id: CCO:B0068982 name: OR4S2_HUMAN-Phosphoserine227 def: "Protein OR4S2_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q8NH73] xref: UniProtKB:Q8NH73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001322 ! olfactory receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057844 ! OR4S2_HUMAN [Term] id: CCO:B0068983 name: ORC1_HUMAN-Phosphoserine196 def: "Protein ORC1_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0068984 name: ORC1_HUMAN-Phosphothreonine203 def: "Protein ORC1_HUMAN with the residue 203 substituted with Phosphothreonine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0068985 name: ORC1_HUMAN-Phosphothreonine337 def: "Protein ORC1_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0068986 name: ORC1_HUMAN-Phosphoserine340 def: "Protein ORC1_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0068987 name: ORC1_HUMAN-Phosphoserine427 def: "Protein ORC1_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0068988 name: ORC1_HUMAN-Phosphoserine478 def: "Protein ORC1_HUMAN with the residue 478 substituted with Phosphoserine" [UniProtKB:Q13415] xref: UniProtKB:Q13415 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:B0068989 name: ORC2_HUMAN-Phosphothreonine116 def: "Protein ORC2_HUMAN with the residue 116 substituted with Phosphothreonine" [UniProtKB:Q13416] xref: UniProtKB:Q13416 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:B0068990 name: ORC2_HUMAN-Phosphoserine280 def: "Protein ORC2_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q13416] xref: UniProtKB:Q13416 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000280 ! DNA replication origin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000135 ! origin recognition complex relationship: located_in CCO:C0000158 ! inner kinetochore of condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000269 ! nuclear origin of replication recognition complex relationship: transformation_of CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:B0068991 name: ORC3_HUMAN-Phosphoserine23 def: "Protein ORC3_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q9UBD5] xref: UniProtKB:Q9UBD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:B0068992 name: OREX_HUMAN-Pyrrolidone carboxylic acid34 def: "Protein OREX_HUMAN with the residue 34 substituted with Pyrrolidone carboxylic acid" [UniProtKB:O43612] comment: By similarity xref: UniProtKB:O43612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054501 ! OREX_HUMAN [Term] id: CCO:B0068993 name: OREX_HUMAN-Leucine amide66 def: "Protein OREX_HUMAN with the residue 66 substituted with Leucine amide" [UniProtKB:O43612] comment: By similarity xref: UniProtKB:O43612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054501 ! OREX_HUMAN [Term] id: CCO:B0068994 name: OREX_HUMAN-Methionine amide97 def: "Protein OREX_HUMAN with the residue 97 substituted with Methionine amide" [UniProtKB:O43612] comment: By similarity xref: UniProtKB:O43612 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000372 ! rough endoplasmic reticulum relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0054501 ! OREX_HUMAN [Term] id: CCO:B0068995 name: OSMR_HUMAN-Phosphoserine826 def: "Protein OSMR_HUMAN with the residue 826 substituted with Phosphoserine" [UniProtKB:Q99650] xref: UniProtKB:Q99650 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058434 ! OSMR_HUMAN [Term] id: CCO:B0068996 name: OSMR_HUMAN-Phosphotyrosine837 def: "Protein OSMR_HUMAN with the residue 837 substituted with Phosphotyrosine" [UniProtKB:Q99650] xref: UniProtKB:Q99650 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity relationship: has_function CCO:F0001269 ! oncostatin-M receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000457 ! oncostatin-M receptor complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058434 ! OSMR_HUMAN [Term] id: CCO:B0068997 name: OSMR_HUMAN-Phosphoserine889 def: "Protein OSMR_HUMAN with the residue 889 substituted with Phosphoserine" [UniProtKB:Q99650] xref: UniProtKB:Q99650 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058434 ! OSMR_HUMAN [Term] id: CCO:B0068998 name: OSTC_HUMAN-4-carboxyglutamate68 def: "Protein OSTC_HUMAN with the residue 68 substituted with 4-carboxyglutamate" [UniProtKB:P02818] comment: partial; xref: UniProtKB:P02818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054878 ! OSTC_HUMAN [Term] id: CCO:B0068999 name: OSTC_HUMAN-4-carboxyglutamate72 def: "Protein OSTC_HUMAN with the residue 72 substituted with 4-carboxyglutamate" [UniProtKB:P02818] xref: UniProtKB:P02818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054878 ! OSTC_HUMAN [Term] id: CCO:B0069000 name: OSTC_HUMAN-4-carboxyglutamate75 def: "Protein OSTC_HUMAN with the residue 75 substituted with 4-carboxyglutamate" [UniProtKB:P02818] xref: UniProtKB:P02818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001749 ! structural constituent of bone relationship: has_function CCO:F0006252 ! hydroxyapatite binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0054878 ! OSTC_HUMAN [Term] id: CCO:B0069001 name: OSTF1_HUMAN-Phosphothreonine200 def: "Protein OSTF1_HUMAN with the residue 200 substituted with Phosphothreonine" [UniProtKB:Q92882] xref: UniProtKB:Q92882 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058109 ! OSTF1_HUMAN [Term] id: CCO:B0069002 name: OSTF1_HUMAN-Phosphoserine202 def: "Protein OSTF1_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q92882] xref: UniProtKB:Q92882 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058109 ! OSTF1_HUMAN [Term] id: CCO:B0069003 name: OSTF1_HUMAN-Phosphoserine213 def: "Protein OSTF1_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:Q92882] xref: UniProtKB:Q92882 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058109 ! OSTF1_HUMAN [Term] id: CCO:B0069004 name: OSTN_HUMAN-Arginine amide132 def: "Protein OSTN_HUMAN with the residue 132 substituted with Arginine amide" [UniProtKB:P61366] comment: Potential xref: UniProtKB:P61366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: transformation_of CCO:B0055609 ! OSTN_HUMAN [Term] id: CCO:B0069005 name: OTU7B_HUMAN-Phosphoserine100 def: "Protein OTU7B_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q6GQQ9] xref: UniProtKB:Q6GQQ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056735 ! OTU7B_HUMAN [Term] id: CCO:B0069006 name: OTU7B_HUMAN-Phosphoserine449 def: "Protein OTU7B_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q6GQQ9] xref: UniProtKB:Q6GQQ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056735 ! OTU7B_HUMAN [Term] id: CCO:B0069007 name: OX1R_HUMAN-Phosphotyrosine27 def: "Protein OX1R_HUMAN with the residue 27 substituted with Phosphotyrosine" [UniProtKB:O43613] xref: UniProtKB:O43613 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0003180 ! orexin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054502 ! OX1R_HUMAN [Term] id: CCO:B0069008 name: OX26_HUMAN-Pyrrolidone carboxylic acid91 def: "Protein OX26_HUMAN with the residue 91 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P83859] comment: By similarity xref: UniProtKB:P83859 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055661 ! OX26_HUMAN [Term] id: CCO:B0069009 name: OX26_HUMAN-Phenylalanine amide133 def: "Protein OX26_HUMAN with the residue 133 substituted with Phenylalanine amide" [UniProtKB:P83859] comment: By similarity xref: UniProtKB:P83859 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055661 ! OX26_HUMAN [Term] id: CCO:B0069010 name: OXSR1_HUMAN-Phosphoserine339 def: "Protein OXSR1_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:O95747] xref: UniProtKB:O95747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054791 ! OXSR1_HUMAN [Term] id: CCO:B0069011 name: OXSR1_HUMAN-Phosphoserine427 def: "Protein OXSR1_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:O95747] xref: UniProtKB:O95747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054791 ! OXSR1_HUMAN [Term] id: CCO:B0069012 name: P2R3B_HUMAN-Phosphotyrosine184 def: "Protein P2R3B_HUMAN with the residue 184 substituted with Phosphotyrosine" [UniProtKB:Q9Y5P8] xref: UniProtKB:Q9Y5P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002258 ! P2R3B_HUMAN [Term] id: CCO:B0069013 name: P2RX4_HUMAN-Phosphotyrosine378 def: "Protein P2RX4_HUMAN with the residue 378 substituted with Phosphotyrosine" [UniProtKB:Q99571] comment: By similarity xref: UniProtKB:Q99571 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058423 ! P2RX4_HUMAN [Term] id: CCO:B0069014 name: P2RX5_HUMAN-Phosphotyrosine55 def: "Protein P2RX5_HUMAN with the residue 55 substituted with Phosphotyrosine" [UniProtKB:Q93086] xref: UniProtKB:Q93086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000165 ! purinergic nucleotide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001273 ! ATP-gated cation channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058122 ! P2RX5_HUMAN [Term] id: CCO:B0069015 name: P2RX6_HUMAN-Phosphotyrosine54 def: "Protein P2RX6_HUMAN with the residue 54 substituted with Phosphotyrosine" [UniProtKB:O15547] xref: UniProtKB:O15547 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000165 ! purinergic nucleotide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001273 ! ATP-gated cation channel activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002725 ! channel activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0054447 ! P2RX6_HUMAN [Term] id: CCO:B0069016 name: P2RX7_HUMAN-Phosphotyrosine343 def: "Protein P2RX7_HUMAN with the residue 343 substituted with Phosphotyrosine" [UniProtKB:Q99572] xref: UniProtKB:Q99572 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000132 ! lipopolysaccharide binding relationship: has_function CCO:F0000165 ! purinergic nucleotide receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001273 ! ATP-gated cation channel activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001391 ! bleb relationship: transformation_of CCO:B0058424 ! P2RX7_HUMAN [Term] id: CCO:B0069017 name: P2RY1_HUMAN-Phosphoserine352 def: "Protein P2RY1_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:P47900] xref: UniProtKB:P47900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055394 ! P2RY1_HUMAN [Term] id: CCO:B0069018 name: P2RY1_HUMAN-Phosphoserine354 def: "Protein P2RY1_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:P47900] xref: UniProtKB:P47900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055394 ! P2RY1_HUMAN [Term] id: CCO:B0069019 name: P2RY4_HUMAN-Phosphoserine333 def: "Protein P2RY4_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:P51582] comment: Probable xref: UniProtKB:P51582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055469 ! P2RY4_HUMAN [Term] id: CCO:B0069020 name: P2RY4_HUMAN-Phosphoserine334 def: "Protein P2RY4_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:P51582] comment: Probable xref: UniProtKB:P51582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0002552 ! uridine nucleotide receptor activity relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_function CCO:F0006065 ! UTP-activated nucleotide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055469 ! P2RY4_HUMAN [Term] id: CCO:B0069021 name: P34_HUMAN-Phosphoserine310 def: "Protein P34_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q6PD74] xref: UniProtKB:Q6PD74 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063460 ! P34_HUMAN [Term] id: CCO:B0069022 name: P34_HUMAN-Phosphoserine311 def: "Protein P34_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q6PD74] xref: UniProtKB:Q6PD74 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063460 ! P34_HUMAN [Term] id: CCO:B0069023 name: P3C2G_HUMAN-Phosphotyrosine419 def: "Protein P3C2G_HUMAN with the residue 419 substituted with Phosphotyrosine" [UniProtKB:O75747] xref: UniProtKB:O75747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054663 ! P3C2G_HUMAN [Term] id: CCO:B0069024 name: P55G_HUMAN-Phosphotyrosine199 def: "Protein P55G_HUMAN with the residue 199 substituted with Phosphotyrosine" [UniProtKB:Q92569] comment: By similarity xref: UniProtKB:Q92569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0005556 ! phosphoinositide 3-kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: transformation_of CCO:B0026600 ! P55G_HUMAN [Term] id: CCO:B0069025 name: P55G_HUMAN-Phosphotyrosine341 def: "Protein P55G_HUMAN with the residue 341 substituted with Phosphotyrosine" [UniProtKB:Q92569] comment: By similarity xref: UniProtKB:Q92569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026600 ! P55G_HUMAN [Term] id: CCO:B0069026 name: P66A_HUMAN-Phosphoserine340 def: "Protein P66A_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0069027 name: P66A_HUMAN-Phosphoserine548 def: "Protein P66A_HUMAN with the residue 548 substituted with Phosphoserine" [UniProtKB:Q86YP4] xref: UniProtKB:Q86YP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:B0069028 name: P66B_HUMAN-Phosphoserine134 def: "Protein P66B_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0069029 name: P66B_HUMAN-Phosphoserine333 def: "Protein P66B_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q8WXI9] xref: UniProtKB:Q8WXI9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:B0069030 name: P80C_HUMAN-Phosphoserine271 def: "Protein P80C_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:P38432] xref: UniProtKB:P38432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:B0069031 name: P80C_HUMAN-Phosphothreonine290 def: "Protein P80C_HUMAN with the residue 290 substituted with Phosphothreonine" [UniProtKB:P38432] xref: UniProtKB:P38432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:B0069032 name: P80C_HUMAN-Phosphoserine301 def: "Protein P80C_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:P38432] xref: UniProtKB:P38432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:B0069033 name: P85A_HUMAN-Phosphotyrosine452 def: "Protein P85A_HUMAN with the residue 452 substituted with Phosphotyrosine" [UniProtKB:P27986] xref: UniProtKB:P27986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:B0069034 name: P85A_HUMAN-Phosphotyrosine467 def: "Protein P85A_HUMAN with the residue 467 substituted with Phosphotyrosine" [UniProtKB:P27986] xref: UniProtKB:P27986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001461 ! insulin-like growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_function CCO:F0004212 ! protein phosphatase binding relationship: has_function CCO:F0005556 ! phosphoinositide 3-kinase regulator activity relationship: has_function CCO:F0005796 ! ErbB-3 class receptor binding relationship: has_function CCO:F0005874 ! insulin binding relationship: has_function CCO:F0005875 ! insulin receptor substrate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: located_in CCO:C0002115 ! 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex relationship: transformation_of CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:B0069035 name: P85A_HUMAN-Phosphotyrosine556 def: "Protein P85A_HUMAN with the residue 556 substituted with Phosphotyrosine" [UniProtKB:P27986] xref: UniProtKB:P27986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:B0069036 name: P85A_HUMAN-Phosphotyrosine580 def: "Protein P85A_HUMAN with the residue 580 substituted with Phosphotyrosine" [UniProtKB:P27986] xref: UniProtKB:P27986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:B0069037 name: P85A_HUMAN-Phosphotyrosine607 def: "Protein P85A_HUMAN with the residue 607 substituted with Phosphotyrosine" [UniProtKB:P27986] xref: UniProtKB:P27986 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:B0069038 name: P85B_HUMAN-Phosphotyrosine365 def: "Protein P85B_HUMAN with the residue 365 substituted with Phosphotyrosine" [UniProtKB:O00459] xref: UniProtKB:O00459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026602 ! P85B_HUMAN [Term] id: CCO:B0069039 name: P85B_HUMAN-Phosphotyrosine464 def: "Protein P85B_HUMAN with the residue 464 substituted with Phosphotyrosine" [UniProtKB:O00459] xref: UniProtKB:O00459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026602 ! P85B_HUMAN [Term] id: CCO:B0069040 name: P85B_HUMAN-Phosphotyrosine467 def: "Protein P85B_HUMAN with the residue 467 substituted with Phosphotyrosine" [UniProtKB:O00459] xref: UniProtKB:O00459 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003115 ! 1-phosphatidylinositol-3-kinase activity relationship: has_function CCO:F0005556 ! phosphoinositide 3-kinase regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: transformation_of CCO:B0026602 ! P85B_HUMAN [Term] id: CCO:B0069041 name: PA24C_HUMAN-Phosphotyrosine530 def: "Protein PA24C_HUMAN with the residue 530 substituted with Phosphotyrosine" [UniProtKB:Q9UP65] xref: UniProtKB:Q9UP65 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059258 ! PA24C_HUMAN [Term] id: CCO:B0069042 name: PA24C_HUMAN-Cysteine methyl ester538 def: "Protein PA24C_HUMAN with the residue 538 substituted with Cysteine methyl ester" [UniProtKB:Q9UP65] xref: UniProtKB:Q9UP65 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000999 ! phospholipase activity relationship: has_function CCO:F0001002 ! phospholipase A2 activity relationship: has_function CCO:F0001666 ! phospholipid binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006803 ! calcium-independent phospholipase A2 activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059258 ! PA24C_HUMAN [Term] id: CCO:B0069043 name: PA2G4_HUMAN-Phosphoserine361 def: "Protein PA2G4_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9UQ80] xref: UniProtKB:Q9UQ80 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:B0069044 name: PACN1_HUMAN-Phosphotyrosine394 def: "Protein PACN1_HUMAN with the residue 394 substituted with Phosphotyrosine" [UniProtKB:Q9BY11] comment: By similarity xref: UniProtKB:Q9BY11 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063480 ! PACN1_HUMAN [Term] id: CCO:B0069045 name: PACN3_HUMAN-Phosphoserine276 def: "Protein PACN3_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q9UKS6] xref: UniProtKB:Q9UKS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:B0069046 name: PACN3_HUMAN-Phosphoserine319 def: "Protein PACN3_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q9UKS6] xref: UniProtKB:Q9UKS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:B0069047 name: PACN3_HUMAN-Phosphothreonine324 def: "Protein PACN3_HUMAN with the residue 324 substituted with Phosphothreonine" [UniProtKB:Q9UKS6] xref: UniProtKB:Q9UKS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:B0069048 name: PACN3_HUMAN-Phosphoserine327 def: "Protein PACN3_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:Q9UKS6] xref: UniProtKB:Q9UKS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:B0069049 name: PACN3_HUMAN-Phosphoserine354 def: "Protein PACN3_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q9UKS6] xref: UniProtKB:Q9UKS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:B0069050 name: PACN3_HUMAN-Phosphoserine383 def: "Protein PACN3_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q9UKS6] xref: UniProtKB:Q9UKS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:B0069051 name: PAF1_HUMAN-Phosphoserine456 def: "Protein PAF1_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:Q8N7H5] xref: UniProtKB:Q8N7H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057502 ! PAF1_HUMAN [Term] id: CCO:B0069052 name: PAF1_HUMAN-Phosphoserine460 def: "Protein PAF1_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q8N7H5] xref: UniProtKB:Q8N7H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057502 ! PAF1_HUMAN [Term] id: CCO:B0069053 name: PAF1_HUMAN-Phosphoserine466 def: "Protein PAF1_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q8N7H5] xref: UniProtKB:Q8N7H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057502 ! PAF1_HUMAN [Term] id: CCO:B0069054 name: PAG1_HUMAN-Phosphotyrosine163 def: "Protein PAG1_HUMAN with the residue 163 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] comment: By similarity xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069055 name: PAG1_HUMAN-Phosphotyrosine181 def: "Protein PAG1_HUMAN with the residue 181 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] comment: By similarity xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069056 name: PAG1_HUMAN-Phosphotyrosine227 def: "Protein PAG1_HUMAN with the residue 227 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] comment: By similarity xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069057 name: PAG1_HUMAN-Phosphotyrosine317 def: "Protein PAG1_HUMAN with the residue 317 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] comment: by FYN; xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069058 name: PAG1_HUMAN-Phosphotyrosine341 def: "Protein PAG1_HUMAN with the residue 341 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069059 name: PAG1_HUMAN-Phosphotyrosine359 def: "Protein PAG1_HUMAN with the residue 359 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069060 name: PAG1_HUMAN-Phosphotyrosine387 def: "Protein PAG1_HUMAN with the residue 387 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] comment: By similarity xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069061 name: PAG1_HUMAN-Phosphotyrosine417 def: "Protein PAG1_HUMAN with the residue 417 substituted with Phosphotyrosine" [UniProtKB:Q9NWQ8] xref: UniProtKB:Q9NWQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:B0069062 name: PAIRB_HUMAN-Phosphothreonine255 def: "Protein PAIRB_HUMAN with the residue 255 substituted with Phosphothreonine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000314 ! mRNA 3'-UTR binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0069063 name: PAIRB_HUMAN-Phosphoserine394 def: "Protein PAIRB_HUMAN with the residue 394 substituted with Phosphoserine" [UniProtKB:Q8NC51] xref: UniProtKB:Q8NC51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:B0069064 name: PAK1_HUMAN-Phosphothreonine230 def: "Protein PAK1_HUMAN with the residue 230 substituted with Phosphothreonine" [UniProtKB:Q13153] xref: UniProtKB:Q13153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:B0069065 name: PAK2_HUMAN-Phosphoserine58 def: "Protein PAK2_HUMAN with the residue 58 substituted with Phosphoserine" [UniProtKB:Q13177] xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0069066 name: PAK2_HUMAN-Phosphothreonine169 def: "Protein PAK2_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:Q13177] xref: UniProtKB:Q13177 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:B0069067 name: PAK4_HUMAN-Phosphoserine99 def: "Protein PAK4_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069068 name: PAK4_HUMAN-Phosphoserine104 def: "Protein PAK4_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069069 name: PAK4_HUMAN-Phosphoserine148 def: "Protein PAK4_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069070 name: PAK4_HUMAN-Phosphoserine167 def: "Protein PAK4_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069071 name: PAK4_HUMAN-Phosphoserine181 def: "Protein PAK4_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069072 name: PAK4_HUMAN-Phosphothreonine207 def: "Protein PAK4_HUMAN with the residue 207 substituted with Phosphothreonine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069073 name: PAK4_HUMAN-Phosphoserine267 def: "Protein PAK4_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069074 name: PAK4_HUMAN-Phosphoserine291 def: "Protein PAK4_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:O96013] xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069075 name: PAK4_HUMAN-Phosphoserine474 def: "Protein PAK4_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:O96013] comment: by autocatalysis; xref: UniProtKB:O96013 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:B0069076 name: PAK7_HUMAN-Phosphoserine104 def: "Protein PAK7_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:Q9P286] comment: By similarity xref: UniProtKB:Q9P286 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059054 ! PAK7_HUMAN [Term] id: CCO:B0069077 name: PAK7_HUMAN-Phosphothreonine107 def: "Protein PAK7_HUMAN with the residue 107 substituted with Phosphothreonine" [UniProtKB:Q9P286] comment: By similarity xref: UniProtKB:Q9P286 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0059054 ! PAK7_HUMAN [Term] id: CCO:B0069078 name: PALM2_HUMAN-Phosphoserine318 def: "Protein PALM2_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q8IXS6] xref: UniProtKB:Q8IXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057380 ! PALM2_HUMAN [Term] id: CCO:B0069079 name: PALM2_HUMAN-Phosphoserine358 def: "Protein PALM2_HUMAN with the residue 358 substituted with Phosphoserine" [UniProtKB:Q8IXS6] comment: By similarity xref: UniProtKB:Q8IXS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057380 ! PALM2_HUMAN [Term] id: CCO:B0069080 name: PALMD_HUMAN-Phosphoserine135 def: "Protein PALMD_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q9NP74] xref: UniProtKB:Q9NP74 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058837 ! PALMD_HUMAN [Term] id: CCO:B0069081 name: PALMD_HUMAN-Phosphoserine321 def: "Protein PALMD_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q9NP74] xref: UniProtKB:Q9NP74 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058837 ! PALMD_HUMAN [Term] id: CCO:B0069082 name: PALMD_HUMAN-Phosphoserine370 def: "Protein PALMD_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:Q9NP74] xref: UniProtKB:Q9NP74 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058837 ! PALMD_HUMAN [Term] id: CCO:B0069083 name: PALMD_HUMAN-Phosphoserine385 def: "Protein PALMD_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:Q9NP74] comment: By similarity xref: UniProtKB:Q9NP74 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058837 ! PALMD_HUMAN [Term] id: CCO:B0069084 name: PALMD_HUMAN-Phosphoserine515 def: "Protein PALMD_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:Q9NP74] xref: UniProtKB:Q9NP74 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058837 ! PALMD_HUMAN [Term] id: CCO:B0069085 name: PALM_HUMAN-Phosphothreonine141 def: "Protein PALM_HUMAN with the residue 141 substituted with Phosphothreonine" [UniProtKB:O75781] xref: UniProtKB:O75781 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054665 ! PALM_HUMAN [Term] id: CCO:B0069086 name: PALM_HUMAN-Phosphothreonine145 def: "Protein PALM_HUMAN with the residue 145 substituted with Phosphothreonine" [UniProtKB:O75781] xref: UniProtKB:O75781 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054665 ! PALM_HUMAN [Term] id: CCO:B0069087 name: PALM_HUMAN-Phosphoserine152 def: "Protein PALM_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:O75781] comment: By similarity xref: UniProtKB:O75781 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054665 ! PALM_HUMAN [Term] id: CCO:B0069088 name: PALM_HUMAN-Phosphothreonine158 def: "Protein PALM_HUMAN with the residue 158 substituted with Phosphothreonine" [UniProtKB:O75781] comment: By similarity xref: UniProtKB:O75781 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: transformation_of CCO:B0054665 ! PALM_HUMAN [Term] id: CCO:B0069089 name: PALM_HUMAN-Phosphoserine346 def: "Protein PALM_HUMAN with the residue 346 substituted with Phosphoserine" [UniProtKB:O75781] comment: By similarity xref: UniProtKB:O75781 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054665 ! PALM_HUMAN [Term] id: CCO:B0069090 name: PALM_HUMAN-Phosphothreonine367 def: "Protein PALM_HUMAN with the residue 367 substituted with Phosphothreonine" [UniProtKB:O75781] comment: By similarity xref: UniProtKB:O75781 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054665 ! PALM_HUMAN [Term] id: CCO:B0069091 name: PALM_HUMAN-Phosphoserine369 def: "Protein PALM_HUMAN with the residue 369 substituted with Phosphoserine" [UniProtKB:O75781] comment: By similarity xref: UniProtKB:O75781 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054665 ! PALM_HUMAN [Term] id: CCO:B0069092 name: PAPOA_HUMAN-Phosphoserine24 def: "Protein PAPOA_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:P51003] xref: UniProtKB:P51003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001025 ! polynucleotide adenylyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063134 ! PAPOA_HUMAN [Term] id: CCO:B0069093 name: PAPOA_HUMAN-Phosphoserine553 def: "Protein PAPOA_HUMAN with the residue 553 substituted with Phosphoserine" [UniProtKB:P51003] xref: UniProtKB:P51003 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063134 ! PAPOA_HUMAN [Term] id: CCO:B0069094 name: PAR12_HUMAN-Phosphoserine258 def: "Protein PAR12_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q9H0J9] xref: UniProtKB:Q9H0J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006037 ! PAR12_HUMAN [Term] id: CCO:B0069095 name: PAR12_HUMAN-Phosphoserine263 def: "Protein PAR12_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q9H0J9] xref: UniProtKB:Q9H0J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006037 ! PAR12_HUMAN [Term] id: CCO:B0069096 name: PAR3L_HUMAN-Phosphotyrosine1000 def: "Protein PAR3L_HUMAN with the residue 1000 substituted with Phosphotyrosine" [UniProtKB:Q8TEW8] xref: UniProtKB:Q8TEW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001997 ! PAR3L_HUMAN [Term] id: CCO:B0069097 name: PARD3_HUMAN-Phosphotyrosine489 def: "Protein PARD3_HUMAN with the residue 489 substituted with Phosphotyrosine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0069098 name: PARD3_HUMAN-Phosphoserine692 def: "Protein PARD3_HUMAN with the residue 692 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0069099 name: PARD3_HUMAN-Phosphoserine809 def: "Protein PARD3_HUMAN with the residue 809 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0069100 name: PARD3_HUMAN-Phosphoserine873 def: "Protein PARD3_HUMAN with the residue 873 substituted with Phosphoserine" [UniProtKB:Q8TEW0] xref: UniProtKB:Q8TEW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:B0069101 name: PARF_HUMAN-Phosphoserine402 def: "Protein PARF_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069102 name: PARF_HUMAN-Phosphoserine425 def: "Protein PARF_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069103 name: PARF_HUMAN-Phosphoserine427 def: "Protein PARF_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069104 name: PARF_HUMAN-Phosphoserine454 def: "Protein PARF_HUMAN with the residue 454 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069105 name: PARF_HUMAN-Phosphoserine464 def: "Protein PARF_HUMAN with the residue 464 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069106 name: PARF_HUMAN-Phosphoserine470 def: "Protein PARF_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069107 name: PARF_HUMAN-Phosphoserine471 def: "Protein PARF_HUMAN with the residue 471 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069108 name: PARF_HUMAN-Phosphoserine577 def: "Protein PARF_HUMAN with the residue 577 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069109 name: PARF_HUMAN-Phosphoserine580 def: "Protein PARF_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069110 name: PARF_HUMAN-Phosphoserine596 def: "Protein PARF_HUMAN with the residue 596 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069111 name: PARF_HUMAN-Phosphothreonine599 def: "Protein PARF_HUMAN with the residue 599 substituted with Phosphothreonine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069112 name: PARF_HUMAN-Phosphoserine640 def: "Protein PARF_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069113 name: PARF_HUMAN-Phosphoserine641 def: "Protein PARF_HUMAN with the residue 641 substituted with Phosphoserine" [UniProtKB:Q3YEC7] xref: UniProtKB:Q3YEC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056279 ! PARF_HUMAN [Term] id: CCO:B0069114 name: PARP1_HUMAN-N-acetylalanine2 def: "Protein PARP1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P09874] xref: UniProtKB:P09874 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:B0069115 name: PARVA_HUMAN-Phosphoserine14 def: "Protein PARVA_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q9NVD7] xref: UniProtKB:Q9NVD7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062876 ! PARVA_HUMAN [Term] id: CCO:B0069116 name: PARVA_HUMAN-Phosphoserine19 def: "Protein PARVA_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q9NVD7] xref: UniProtKB:Q9NVD7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0062876 ! PARVA_HUMAN [Term] id: CCO:B0069117 name: PARVA_HUMAN-Phosphothreonine36 def: "Protein PARVA_HUMAN with the residue 36 substituted with Phosphothreonine" [UniProtKB:Q9NVD7] xref: UniProtKB:Q9NVD7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062876 ! PARVA_HUMAN [Term] id: CCO:B0069118 name: PASK_HUMAN-Phosphoserine116 def: "Protein PASK_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069119 name: PASK_HUMAN-Phosphoserine524 def: "Protein PASK_HUMAN with the residue 524 substituted with Phosphoserine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069120 name: PASK_HUMAN-Phosphoserine533 def: "Protein PASK_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069121 name: PASK_HUMAN-Phosphothreonine1161 def: "Protein PASK_HUMAN with the residue 1161 substituted with Phosphothreonine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069122 name: PASK_HUMAN-Phosphothreonine1165 def: "Protein PASK_HUMAN with the residue 1165 substituted with Phosphothreonine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069123 name: PASK_HUMAN-Phosphoserine1273 def: "Protein PASK_HUMAN with the residue 1273 substituted with Phosphoserine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069124 name: PASK_HUMAN-Phosphoserine1277 def: "Protein PASK_HUMAN with the residue 1277 substituted with Phosphoserine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069125 name: PASK_HUMAN-Phosphoserine1280 def: "Protein PASK_HUMAN with the residue 1280 substituted with Phosphoserine" [UniProtKB:Q96RG2] xref: UniProtKB:Q96RG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058375 ! PASK_HUMAN [Term] id: CCO:B0069126 name: PAWR_HUMAN-Phosphothreonine163 def: "Protein PAWR_HUMAN with the residue 163 substituted with Phosphothreonine" [UniProtKB:Q96IZ0] comment: by PKA; By similarity xref: UniProtKB:Q96IZ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058234 ! PAWR_HUMAN [Term] id: CCO:B0069127 name: PAWR_HUMAN-Phosphotyrosine226 def: "Protein PAWR_HUMAN with the residue 226 substituted with Phosphotyrosine" [UniProtKB:Q96IZ0] xref: UniProtKB:Q96IZ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058234 ! PAWR_HUMAN [Term] id: CCO:B0069128 name: PAWR_HUMAN-Phosphoserine228 def: "Protein PAWR_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q96IZ0] xref: UniProtKB:Q96IZ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058234 ! PAWR_HUMAN [Term] id: CCO:B0069129 name: PAWR_HUMAN-Phosphothreonine229 def: "Protein PAWR_HUMAN with the residue 229 substituted with Phosphothreonine" [UniProtKB:Q96IZ0] xref: UniProtKB:Q96IZ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058234 ! PAWR_HUMAN [Term] id: CCO:B0069130 name: PAWR_HUMAN-Phosphoserine231 def: "Protein PAWR_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q96IZ0] xref: UniProtKB:Q96IZ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058234 ! PAWR_HUMAN [Term] id: CCO:B0069131 name: PAX8_HUMAN-Phosphothreonine279 def: "Protein PAX8_HUMAN with the residue 279 substituted with Phosphothreonine" [UniProtKB:Q06710] comment: By similarity xref: UniProtKB:Q06710 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055771 ! PAX8_HUMAN [Term] id: CCO:B0069132 name: PAX8_HUMAN-Phosphothreonine283 def: "Protein PAX8_HUMAN with the residue 283 substituted with Phosphothreonine" [UniProtKB:Q06710] comment: By similarity xref: UniProtKB:Q06710 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055771 ! PAX8_HUMAN [Term] id: CCO:B0069133 name: PAXI_HUMAN-Phosphoserine85 def: "Protein PAXI_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0069134 name: PAXI_HUMAN-Phosphoserine126 def: "Protein PAXI_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0069135 name: PAXI_HUMAN-Phosphoserine130 def: "Protein PAXI_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0069136 name: PAXI_HUMAN-Phosphoserine137 def: "Protein PAXI_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:P49023] xref: UniProtKB:P49023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005837 ! PAXI_HUMAN [Term] id: CCO:B0069137 name: PB1_HUMAN-Phosphoserine131 def: "Protein PB1_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0069138 name: PB1_HUMAN-Phosphoserine314 def: "Protein PB1_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0069139 name: PB1_HUMAN-Phosphoserine316 def: "Protein PB1_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0069140 name: PB1_HUMAN-Phosphoserine319 def: "Protein PB1_HUMAN with the residue 319 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0069141 name: PB1_HUMAN-Phosphoserine353 def: "Protein PB1_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0069142 name: PB1_HUMAN-Phosphoserine355 def: "Protein PB1_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0069143 name: PB1_HUMAN-Phosphoserine1405 def: "Protein PB1_HUMAN with the residue 1405 substituted with Phosphoserine" [UniProtKB:Q86U86] xref: UniProtKB:Q86U86 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001938 ! PB1_HUMAN [Term] id: CCO:B0069144 name: PBIP1_HUMAN-Phosphoserine45 def: "Protein PBIP1_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q96AQ6] xref: UniProtKB:Q96AQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058154 ! PBIP1_HUMAN [Term] id: CCO:B0069145 name: PBIP1_HUMAN-Phosphoserine146 def: "Protein PBIP1_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q96AQ6] xref: UniProtKB:Q96AQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058154 ! PBIP1_HUMAN [Term] id: CCO:B0069146 name: PBIP1_HUMAN-Phosphoserine147 def: "Protein PBIP1_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:Q96AQ6] xref: UniProtKB:Q96AQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058154 ! PBIP1_HUMAN [Term] id: CCO:B0069147 name: PBIP1_HUMAN-Phosphoserine148 def: "Protein PBIP1_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q96AQ6] xref: UniProtKB:Q96AQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058154 ! PBIP1_HUMAN [Term] id: CCO:B0069148 name: PBIP1_HUMAN-Phosphothreonine152 def: "Protein PBIP1_HUMAN with the residue 152 substituted with Phosphothreonine" [UniProtKB:Q96AQ6] xref: UniProtKB:Q96AQ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0058154 ! PBIP1_HUMAN [Term] id: CCO:B0069149 name: PBX2_HUMAN-Phosphoserine330 def: "Protein PBX2_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:P40425] xref: UniProtKB:P40425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0008012 ! advanced glycation end-product receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:B0069150 name: PBX3_HUMAN-Phosphoserine121 def: "Protein PBX3_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:P40426] xref: UniProtKB:P40426 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055330 ! PBX3_HUMAN [Term] id: CCO:B0069151 name: PCAF_HUMAN-Phosphotyrosine729 def: "Protein PCAF_HUMAN with the residue 729 substituted with Phosphotyrosine" [UniProtKB:Q92831] xref: UniProtKB:Q92831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002019 ! PCAF_HUMAN [Term] id: CCO:B0069152 name: PCGF2_HUMAN-Phosphothreonine344 def: "Protein PCGF2_HUMAN with the residue 344 substituted with Phosphothreonine" [UniProtKB:P35227] xref: UniProtKB:P35227 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055280 ! PCGF2_HUMAN [Term] id: CCO:B0069153 name: PCNP_HUMAN-Phosphoserine87 def: "Protein PCNP_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0069154 name: PCNP_HUMAN-Phosphoserine119 def: "Protein PCNP_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q8WW12] xref: UniProtKB:Q8WW12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002005 ! PCNP_HUMAN [Term] id: CCO:B0069155 name: PCSK9_HUMAN-Phosphoserine47 def: "Protein PCSK9_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q8NBP7] xref: UniProtKB:Q8NBP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057558 ! PCSK9_HUMAN [Term] id: CCO:B0069156 name: PCSK9_HUMAN-Phosphoserine688 def: "Protein PCSK9_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:Q8NBP7] xref: UniProtKB:Q8NBP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057558 ! PCSK9_HUMAN [Term] id: CCO:B0069157 name: PDC6I_HUMAN-N-acetylalanine2 def: "Protein PDC6I_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q8WUM4] xref: UniProtKB:Q8WUM4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063149 ! PDC6I_HUMAN [Term] id: CCO:B0069158 name: PDC6I_HUMAN-Phosphoserine730 def: "Protein PDC6I_HUMAN with the residue 730 substituted with Phosphoserine" [UniProtKB:Q8WUM4] xref: UniProtKB:Q8WUM4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063149 ! PDC6I_HUMAN [Term] id: CCO:B0069159 name: PDC6I_HUMAN-Phosphothreonine738 def: "Protein PDC6I_HUMAN with the residue 738 substituted with Phosphothreonine" [UniProtKB:Q8WUM4] xref: UniProtKB:Q8WUM4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063149 ! PDC6I_HUMAN [Term] id: CCO:B0069160 name: PDC6I_HUMAN-Phosphothreonine741 def: "Protein PDC6I_HUMAN with the residue 741 substituted with Phosphothreonine" [UniProtKB:Q8WUM4] xref: UniProtKB:Q8WUM4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063149 ! PDC6I_HUMAN [Term] id: CCO:B0069161 name: PDCD4_HUMAN-Phosphoserine78 def: "Protein PDCD4_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:Q53EL6] xref: UniProtKB:Q53EL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001836 ! PDCD4_HUMAN [Term] id: CCO:B0069162 name: PDCD4_HUMAN-Phosphoserine80 def: "Protein PDCD4_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q53EL6] xref: UniProtKB:Q53EL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001836 ! PDCD4_HUMAN [Term] id: CCO:B0069163 name: PDE1B_HUMAN-Phosphoserine466 def: "Protein PDE1B_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q01064] comment: By similarity xref: UniProtKB:Q01064 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000588 ! calmodulin-dependent cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055683 ! PDE1B_HUMAN [Term] id: CCO:B0069164 name: PDE3A_HUMAN-Phosphoserine312 def: "Protein PDE3A_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q14432] xref: UniProtKB:Q14432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055982 ! PDE3A_HUMAN [Term] id: CCO:B0069165 name: PDE3A_HUMAN-Phosphoserine428 def: "Protein PDE3A_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q14432] xref: UniProtKB:Q14432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055982 ! PDE3A_HUMAN [Term] id: CCO:B0069166 name: PDE3A_HUMAN-Phosphothreonine440 def: "Protein PDE3A_HUMAN with the residue 440 substituted with Phosphothreonine" [UniProtKB:Q14432] xref: UniProtKB:Q14432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000590 ! cGMP-inhibited cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055982 ! PDE3A_HUMAN [Term] id: CCO:B0069167 name: PDE3A_HUMAN-Phosphoserine495 def: "Protein PDE3A_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:Q14432] comment: By similarity xref: UniProtKB:Q14432 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055982 ! PDE3A_HUMAN [Term] id: CCO:B0069168 name: PDE3B_HUMAN-Phosphoserine442 def: "Protein PDE3B_HUMAN with the residue 442 substituted with Phosphoserine" [UniProtKB:Q13370] xref: UniProtKB:Q13370 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000590 ! cGMP-inhibited cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055902 ! PDE3B_HUMAN [Term] id: CCO:B0069169 name: PDE3B_HUMAN-Phosphothreonine444 def: "Protein PDE3B_HUMAN with the residue 444 substituted with Phosphothreonine" [UniProtKB:Q13370] xref: UniProtKB:Q13370 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055902 ! PDE3B_HUMAN [Term] id: CCO:B0069170 name: PDE3B_HUMAN-Phosphothreonine625 def: "Protein PDE3B_HUMAN with the residue 625 substituted with Phosphothreonine" [UniProtKB:Q13370] comment: By similarity xref: UniProtKB:Q13370 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055902 ! PDE3B_HUMAN [Term] id: CCO:B0069171 name: PDE4A_HUMAN-Phosphoserine686 def: "Protein PDE4A_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:P27815] comment: Probable xref: UniProtKB:P27815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000587 ! 3',5'-cyclic-AMP phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055195 ! PDE4A_HUMAN [Term] id: CCO:B0069172 name: PDE4A_HUMAN-Phosphoserine688 def: "Protein PDE4A_HUMAN with the residue 688 substituted with Phosphoserine" [UniProtKB:P27815] comment: Probable xref: UniProtKB:P27815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055195 ! PDE4A_HUMAN [Term] id: CCO:B0069173 name: PDE4B_HUMAN-Phosphothreonine184 def: "Protein PDE4B_HUMAN with the residue 184 substituted with Phosphothreonine" [UniProtKB:Q07343] comment: By similarity xref: UniProtKB:Q07343 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000587 ! 3',5'-cyclic-AMP phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000246 ! insoluble fraction relationship: transformation_of CCO:B0055784 ! PDE4B_HUMAN [Term] id: CCO:B0069174 name: PDE4B_HUMAN-Phosphoserine272 def: "Protein PDE4B_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q07343] comment: By similarity xref: UniProtKB:Q07343 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055784 ! PDE4B_HUMAN [Term] id: CCO:B0069175 name: PDE4B_HUMAN-Phosphotyrosine274 def: "Protein PDE4B_HUMAN with the residue 274 substituted with Phosphotyrosine" [UniProtKB:Q07343] comment: By similarity xref: UniProtKB:Q07343 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055784 ! PDE4B_HUMAN [Term] id: CCO:B0069176 name: PDE4C_HUMAN-Phosphothreonine164 def: "Protein PDE4C_HUMAN with the residue 164 substituted with Phosphothreonine" [UniProtKB:Q08493] xref: UniProtKB:Q08493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055790 ! PDE4C_HUMAN [Term] id: CCO:B0069177 name: PDE4C_HUMAN-Phosphothreonine646 def: "Protein PDE4C_HUMAN with the residue 646 substituted with Phosphothreonine" [UniProtKB:Q08493] xref: UniProtKB:Q08493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000587 ! 3',5'-cyclic-AMP phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055790 ! PDE4C_HUMAN [Term] id: CCO:B0069178 name: PDE4D_HUMAN-Phosphoserine18 def: "Protein PDE4D_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q08499] xref: UniProtKB:Q08499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0000587 ! 3',5'-cyclic-AMP phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000246 ! insoluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000383 ! centrosome relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055792 ! PDE4D_HUMAN [Term] id: CCO:B0069179 name: PDE4D_HUMAN-Phosphoserine20 def: "Protein PDE4D_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q08499] xref: UniProtKB:Q08499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055792 ! PDE4D_HUMAN [Term] id: CCO:B0069180 name: PDE4D_HUMAN-Phosphothreonine25 def: "Protein PDE4D_HUMAN with the residue 25 substituted with Phosphothreonine" [UniProtKB:Q08499] xref: UniProtKB:Q08499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055792 ! PDE4D_HUMAN [Term] id: CCO:B0069181 name: PDE4D_HUMAN-Phosphoserine197 def: "Protein PDE4D_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q08499] xref: UniProtKB:Q08499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055792 ! PDE4D_HUMAN [Term] id: CCO:B0069182 name: PDE4D_HUMAN-Phosphoserine202 def: "Protein PDE4D_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q08499] xref: UniProtKB:Q08499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055792 ! PDE4D_HUMAN [Term] id: CCO:B0069183 name: PDE5A_HUMAN-Phosphoserine102 def: "Protein PDE5A_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:O76074] comment: Potential xref: UniProtKB:O76074 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004465 ! cGMP binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006858 ! 3',5'-cyclic-GMP phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0054692 ! PDE5A_HUMAN [Term] id: CCO:B0069184 name: PDE6A_HUMAN-N-acetylglycine2 def: "Protein PDE6A_HUMAN with the residue 2 substituted with N-acetylglycine" [UniProtKB:P16499] comment: By similarity xref: UniProtKB:P16499 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006858 ! 3',5'-cyclic-GMP phosphodiesterase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055055 ! PDE6A_HUMAN [Term] id: CCO:B0069185 name: PDE7B_HUMAN-Phosphoserine45 def: "Protein PDE7B_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q9NP56] xref: UniProtKB:Q9NP56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027477 ! PDE7B_HUMAN [Term] id: CCO:B0069186 name: PDE9A_HUMAN-Phosphotyrosine29 def: "Protein PDE9A_HUMAN with the residue 29 substituted with Phosphotyrosine" [UniProtKB:O76083] xref: UniProtKB:O76083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054693 ! PDE9A_HUMAN [Term] id: CCO:B0069187 name: PDIA6_HUMAN-Phosphoserine428 def: "Protein PDIA6_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q15084] xref: UniProtKB:Q15084 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000320 ! protein disulfide isomerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003416 ! isomerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000369 ! endoplasmic reticulum lumen relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0063257 ! PDIA6_HUMAN [Term] id: CCO:B0069188 name: PDLI7_HUMAN-Phosphoserine247 def: "Protein PDLI7_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:Q9NR12] xref: UniProtKB:Q9NR12 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005224 ! PDLI7_HUMAN [Term] id: CCO:B0069189 name: PDS5A_HUMAN-Phosphoserine1195 def: "Protein PDS5A_HUMAN with the residue 1195 substituted with Phosphoserine" [UniProtKB:Q29RF7] xref: UniProtKB:Q29RF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001829 ! PDS5A_HUMAN [Term] id: CCO:B0069190 name: PDS5B_HUMAN-Phosphoserine1283 def: "Protein PDS5B_HUMAN with the residue 1283 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0069191 name: PDS5B_HUMAN-Phosphoserine1319 def: "Protein PDS5B_HUMAN with the residue 1319 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0069192 name: PDS5B_HUMAN-Phosphoserine1334 def: "Protein PDS5B_HUMAN with the residue 1334 substituted with Phosphoserine" [UniProtKB:Q9NTI5] xref: UniProtKB:Q9NTI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026257 ! PDS5B_HUMAN [Term] id: CCO:B0069193 name: PDZD1_HUMAN-Phosphoserine492 def: "Protein PDZD1_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q5T2W1] comment: By similarity xref: UniProtKB:Q5T2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025068 ! PDZD1_HUMAN [Term] id: CCO:B0069194 name: PDZD1_HUMAN-Phosphoserine514 def: "Protein PDZD1_HUMAN with the residue 514 substituted with Phosphoserine" [UniProtKB:Q5T2W1] comment: By similarity xref: UniProtKB:Q5T2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001426 ! scavenger receptor binding relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0025068 ! PDZD1_HUMAN [Term] id: CCO:B0069195 name: PDZD8_HUMAN-Phosphoserine496 def: "Protein PDZD8_HUMAN with the residue 496 substituted with Phosphoserine" [UniProtKB:Q8NEN9] xref: UniProtKB:Q8NEN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057592 ! PDZD8_HUMAN [Term] id: CCO:B0069196 name: PDZD8_HUMAN-Phosphoserine538 def: "Protein PDZD8_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:Q8NEN9] xref: UniProtKB:Q8NEN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057592 ! PDZD8_HUMAN [Term] id: CCO:B0069197 name: PEA15_HUMAN-Phosphothreonine6 def: "Protein PEA15_HUMAN with the residue 6 substituted with Phosphothreonine" [UniProtKB:Q15121] xref: UniProtKB:Q15121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001577 ! sugar:hydrogen symporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: transformation_of CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:B0069198 name: PEA15_HUMAN-Phosphoserine25 def: "Protein PEA15_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q15121] xref: UniProtKB:Q15121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:B0069199 name: PEA15_HUMAN-Phosphoserine104 def: "Protein PEA15_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:Q15121] xref: UniProtKB:Q15121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:B0069200 name: PEA15_HUMAN-Phosphotyrosine108 def: "Protein PEA15_HUMAN with the residue 108 substituted with Phosphotyrosine" [UniProtKB:Q15121] xref: UniProtKB:Q15121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:B0069201 name: PEA15_HUMAN-Phosphoserine116 def: "Protein PEA15_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q15121] xref: UniProtKB:Q15121 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:B0069202 name: PEBP1_HUMAN-Phosphothreonine42 def: "Protein PEBP1_HUMAN with the residue 42 substituted with Phosphothreonine" [UniProtKB:P30086] xref: UniProtKB:P30086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027514 ! PEBP1_HUMAN [Term] id: CCO:B0069203 name: PEBP1_HUMAN-Phosphoserine52 def: "Protein PEBP1_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:P30086] xref: UniProtKB:P30086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027514 ! PEBP1_HUMAN [Term] id: CCO:B0069204 name: PEBP1_HUMAN-Phosphoserine54 def: "Protein PEBP1_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:P30086] comment: By similarity xref: UniProtKB:P30086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027514 ! PEBP1_HUMAN [Term] id: CCO:B0069205 name: PECA1_HUMAN-Phosphotyrosine290 def: "Protein PECA1_HUMAN with the residue 290 substituted with Phosphotyrosine" [UniProtKB:P16284] xref: UniProtKB:P16284 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0026626 ! PECA1_HUMAN [Term] id: CCO:B0069206 name: PECR_HUMAN-Phosphotyrosine179 def: "Protein PECR_HUMAN with the residue 179 substituted with Phosphotyrosine" [UniProtKB:Q9BY49] xref: UniProtKB:Q9BY49 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004101 ! trans-2-enoyl-CoA reductase (NADPH) activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000359 ! peroxisome relationship: transformation_of CCO:B0058571 ! PECR_HUMAN [Term] id: CCO:B0069207 name: PEDF_HUMAN-Pyrrolidone carboxylic acid20 def: "Protein PEDF_HUMAN with the residue 20 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P36955] xref: UniProtKB:P36955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055315 ! PEDF_HUMAN [Term] id: CCO:B0069208 name: PEDF_HUMAN-Phosphoserine24 def: "Protein PEDF_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:P36955] comment: by CK2; xref: UniProtKB:P36955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0055315 ! PEDF_HUMAN [Term] id: CCO:B0069209 name: PEDF_HUMAN-Phosphoserine114 def: "Protein PEDF_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:P36955] comment: by CK2; xref: UniProtKB:P36955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055315 ! PEDF_HUMAN [Term] id: CCO:B0069210 name: PEDF_HUMAN-Phosphoserine227 def: "Protein PEDF_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P36955] comment: by PKA; xref: UniProtKB:P36955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055315 ! PEDF_HUMAN [Term] id: CCO:B0069211 name: PEPL_HUMAN-Phosphoserine1331 def: "Protein PEPL_HUMAN with the residue 1331 substituted with Phosphoserine" [UniProtKB:O60437] xref: UniProtKB:O60437 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063295 ! PEPL_HUMAN [Term] id: CCO:B0069212 name: PEPL_HUMAN-Phosphothreonine1579 def: "Protein PEPL_HUMAN with the residue 1579 substituted with Phosphothreonine" [UniProtKB:O60437] xref: UniProtKB:O60437 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0063295 ! PEPL_HUMAN [Term] id: CCO:B0069213 name: PER1_HUMAN-Phosphoserine979 def: "Protein PER1_HUMAN with the residue 979 substituted with Phosphoserine" [UniProtKB:O15534] xref: UniProtKB:O15534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054445 ! PER1_HUMAN [Term] id: CCO:B0069214 name: PER1_HUMAN-Phosphoserine980 def: "Protein PER1_HUMAN with the residue 980 substituted with Phosphoserine" [UniProtKB:O15534] xref: UniProtKB:O15534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054445 ! PER1_HUMAN [Term] id: CCO:B0069215 name: PER1_HUMAN-Phosphoserine1100 def: "Protein PER1_HUMAN with the residue 1100 substituted with Phosphoserine" [UniProtKB:O15534] xref: UniProtKB:O15534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054445 ! PER1_HUMAN [Term] id: CCO:B0069216 name: PER1_HUMAN-Phosphoserine1103 def: "Protein PER1_HUMAN with the residue 1103 substituted with Phosphoserine" [UniProtKB:O15534] xref: UniProtKB:O15534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054445 ! PER1_HUMAN [Term] id: CCO:B0069217 name: PER1_HUMAN-Phosphoserine1104 def: "Protein PER1_HUMAN with the residue 1104 substituted with Phosphoserine" [UniProtKB:O15534] xref: UniProtKB:O15534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054445 ! PER1_HUMAN [Term] id: CCO:B0069218 name: PER1_HUMAN-Phosphoserine1262 def: "Protein PER1_HUMAN with the residue 1262 substituted with Phosphoserine" [UniProtKB:O15534] xref: UniProtKB:O15534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054445 ! PER1_HUMAN [Term] id: CCO:B0069219 name: PER1_HUMAN-Phosphoserine1263 def: "Protein PER1_HUMAN with the residue 1263 substituted with Phosphoserine" [UniProtKB:O15534] xref: UniProtKB:O15534 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054445 ! PER1_HUMAN [Term] id: CCO:B0069220 name: PER2_HUMAN-Phosphoserine527 def: "Protein PER2_HUMAN with the residue 527 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069221 name: PER2_HUMAN-Phosphoserine530 def: "Protein PER2_HUMAN with the residue 530 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069222 name: PER2_HUMAN-Phosphoserine533 def: "Protein PER2_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069223 name: PER2_HUMAN-Phosphoserine540 def: "Protein PER2_HUMAN with the residue 540 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069224 name: PER2_HUMAN-Phosphoserine662 def: "Protein PER2_HUMAN with the residue 662 substituted with Phosphoserine" [UniProtKB:O15055] xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069225 name: PER2_HUMAN-Phosphoserine696 def: "Protein PER2_HUMAN with the residue 696 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069226 name: PER2_HUMAN-Phosphoserine700 def: "Protein PER2_HUMAN with the residue 700 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069227 name: PER2_HUMAN-Phosphoserine714 def: "Protein PER2_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069228 name: PER2_HUMAN-Phosphoserine766 def: "Protein PER2_HUMAN with the residue 766 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069229 name: PER2_HUMAN-Phosphoserine771 def: "Protein PER2_HUMAN with the residue 771 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069230 name: PER2_HUMAN-Phosphothreonine864 def: "Protein PER2_HUMAN with the residue 864 substituted with Phosphothreonine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069231 name: PER2_HUMAN-Phosphoserine945 def: "Protein PER2_HUMAN with the residue 945 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069232 name: PER2_HUMAN-Phosphoserine977 def: "Protein PER2_HUMAN with the residue 977 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069233 name: PER2_HUMAN-Phosphoserine1124 def: "Protein PER2_HUMAN with the residue 1124 substituted with Phosphoserine" [UniProtKB:O15055] comment: By similarity xref: UniProtKB:O15055 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:B0069234 name: PERM_HUMAN-Cysteine sulfenic acid (-SOH)316 def: "Protein PERM_HUMAN with the residue 316 substituted with Cysteine sulfenic acid (-SOH)" [UniProtKB:P05164] xref: UniProtKB:P05164 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000981 ! peroxidase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004249 ! heme binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000347 ! lysosome relationship: transformation_of CCO:B0054897 ! PERM_HUMAN [Term] id: CCO:B0069235 name: PERQ1_HUMAN-Phosphoserine638 def: "Protein PERQ1_HUMAN with the residue 638 substituted with Phosphoserine" [UniProtKB:O75420] xref: UniProtKB:O75420 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054633 ! PERQ1_HUMAN [Term] id: CCO:B0069236 name: PESC_HUMAN-Phosphotyrosine548 def: "Protein PESC_HUMAN with the residue 548 substituted with Phosphotyrosine" [UniProtKB:O00541] xref: UniProtKB:O00541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0001351 ! PESC_HUMAN [Term] id: CCO:B0069237 name: PEX14_HUMAN-Phosphoserine335 def: "Protein PEX14_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:O75381] xref: UniProtKB:O75381 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000360 ! peroxisomal membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054627 ! PEX14_HUMAN [Term] id: CCO:B0069238 name: PFD4_HUMAN-Phosphoserine125 def: "Protein PFD4_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q9NQP4] xref: UniProtKB:Q9NQP4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063103 ! PFD4_HUMAN [Term] id: CCO:B0069239 name: PGBD1_HUMAN-Phosphoserine351 def: "Protein PGBD1_HUMAN with the residue 351 substituted with Phosphoserine" [UniProtKB:Q96JS3] xref: UniProtKB:Q96JS3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058249 ! PGBD1_HUMAN [Term] id: CCO:B0069240 name: PGBD1_HUMAN-Phosphoserine360 def: "Protein PGBD1_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q96JS3] xref: UniProtKB:Q96JS3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058249 ! PGBD1_HUMAN [Term] id: CCO:B0069241 name: PGFRA_HUMAN-Phosphotyrosine762 def: "Protein PGFRA_HUMAN with the residue 762 substituted with Phosphotyrosine" [UniProtKB:P16234] xref: UniProtKB:P16234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020505 ! PGFRA_HUMAN [Term] id: CCO:B0069242 name: PGFRA_HUMAN-Phosphotyrosine768 def: "Protein PGFRA_HUMAN with the residue 768 substituted with Phosphotyrosine" [UniProtKB:P16234] xref: UniProtKB:P16234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020505 ! PGFRA_HUMAN [Term] id: CCO:B0069243 name: PGFRA_HUMAN-Phosphotyrosine1018 def: "Protein PGFRA_HUMAN with the residue 1018 substituted with Phosphotyrosine" [UniProtKB:P16234] xref: UniProtKB:P16234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020505 ! PGFRA_HUMAN [Term] id: CCO:B0069244 name: PGTB2_HUMAN-Phosphothreonine3 def: "Protein PGTB2_HUMAN with the residue 3 substituted with Phosphothreonine" [UniProtKB:P53611] xref: UniProtKB:P53611 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001032 ! prenyltransferase activity relationship: has_function CCO:F0001036 ! Rab-protein geranylgeranyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063297 ! PGTB2_HUMAN [Term] id: CCO:B0069245 name: PHB2_HUMAN-Phosphotyrosine128 def: "Protein PHB2_HUMAN with the residue 128 substituted with Phosphotyrosine" [UniProtKB:Q99623] xref: UniProtKB:Q99623 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003208 ! specific transcriptional repressor activity relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000329 ! mitochondrial inner membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058432 ! PHB2_HUMAN [Term] id: CCO:B0069246 name: PHB2_HUMAN-Phosphotyrosine248 def: "Protein PHB2_HUMAN with the residue 248 substituted with Phosphotyrosine" [UniProtKB:Q99623] xref: UniProtKB:Q99623 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058432 ! PHB2_HUMAN [Term] id: CCO:B0069247 name: PHC1_HUMAN-Phosphotyrosine32 def: "Protein PHC1_HUMAN with the residue 32 substituted with Phosphotyrosine" [UniProtKB:P78364] xref: UniProtKB:P78364 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005264 ! PHC1_HUMAN [Term] id: CCO:B0069248 name: PHF10_HUMAN-Phosphoserine182 def: "Protein PHF10_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q8WUB8] xref: UniProtKB:Q8WUB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:B0069249 name: PHF10_HUMAN-Phosphoserine209 def: "Protein PHF10_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q8WUB8] xref: UniProtKB:Q8WUB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:B0069250 name: PHF10_HUMAN-Phosphoserine213 def: "Protein PHF10_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:Q8WUB8] xref: UniProtKB:Q8WUB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:B0069251 name: PHF12_HUMAN-Phosphoserine133 def: "Protein PHF12_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:Q96QT6] xref: UniProtKB:Q96QT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039070 ! PHF12_HUMAN [Term] id: CCO:B0069252 name: PHF12_HUMAN-Phosphoserine134 def: "Protein PHF12_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q96QT6] xref: UniProtKB:Q96QT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039070 ! PHF12_HUMAN [Term] id: CCO:B0069253 name: PHF12_HUMAN-Phosphothreonine671 def: "Protein PHF12_HUMAN with the residue 671 substituted with Phosphothreonine" [UniProtKB:Q96QT6] xref: UniProtKB:Q96QT6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000831 ! transcriptional repressor complex relationship: transformation_of CCO:B0039070 ! PHF12_HUMAN [Term] id: CCO:B0069254 name: PHF20_HUMAN-Phosphoserine209 def: "Protein PHF20_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q9BVI0] xref: UniProtKB:Q9BVI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058527 ! PHF20_HUMAN [Term] id: CCO:B0069255 name: PHF20_HUMAN-Phosphoserine878 def: "Protein PHF20_HUMAN with the residue 878 substituted with Phosphoserine" [UniProtKB:Q9BVI0] xref: UniProtKB:Q9BVI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058527 ! PHF20_HUMAN [Term] id: CCO:B0069256 name: PHF20_HUMAN-Phosphoserine880 def: "Protein PHF20_HUMAN with the residue 880 substituted with Phosphoserine" [UniProtKB:Q9BVI0] xref: UniProtKB:Q9BVI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058527 ! PHF20_HUMAN [Term] id: CCO:B0069257 name: PHF6_HUMAN-Phosphoserine120 def: "Protein PHF6_HUMAN with the residue 120 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069258 name: PHF6_HUMAN-Phosphoserine138 def: "Protein PHF6_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069259 name: PHF6_HUMAN-Phosphoserine145 def: "Protein PHF6_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069260 name: PHF6_HUMAN-Phosphoserine154 def: "Protein PHF6_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069261 name: PHF6_HUMAN-Phosphoserine155 def: "Protein PHF6_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069262 name: PHF6_HUMAN-Phosphoserine199 def: "Protein PHF6_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069263 name: PHF6_HUMAN-Phosphoserine203 def: "Protein PHF6_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069264 name: PHF6_HUMAN-Phosphoserine204 def: "Protein PHF6_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069265 name: PHF6_HUMAN-Phosphothreonine358 def: "Protein PHF6_HUMAN with the residue 358 substituted with Phosphothreonine" [UniProtKB:Q8IWS0] xref: UniProtKB:Q8IWS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057363 ! PHF6_HUMAN [Term] id: CCO:B0069266 name: PHIP_HUMAN-Phosphoserine136 def: "Protein PHIP_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069267 name: PHIP_HUMAN-Phosphotyrosine140 def: "Protein PHIP_HUMAN with the residue 140 substituted with Phosphotyrosine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069268 name: PHIP_HUMAN-Phosphoserine683 def: "Protein PHIP_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069269 name: PHIP_HUMAN-Phosphoserine911 def: "Protein PHIP_HUMAN with the residue 911 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069270 name: PHIP_HUMAN-Phosphoserine1281 def: "Protein PHIP_HUMAN with the residue 1281 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069271 name: PHIP_HUMAN-Phosphoserine1283 def: "Protein PHIP_HUMAN with the residue 1283 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069272 name: PHIP_HUMAN-Phosphoserine1315 def: "Protein PHIP_HUMAN with the residue 1315 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069273 name: PHIP_HUMAN-Phosphoserine1405 def: "Protein PHIP_HUMAN with the residue 1405 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069274 name: PHIP_HUMAN-Phosphoserine1473 def: "Protein PHIP_HUMAN with the residue 1473 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069275 name: PHIP_HUMAN-Phosphoserine1479 def: "Protein PHIP_HUMAN with the residue 1479 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069276 name: PHIP_HUMAN-Phosphothreonine1480 def: "Protein PHIP_HUMAN with the residue 1480 substituted with Phosphothreonine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069277 name: PHIP_HUMAN-Phosphoserine1591 def: "Protein PHIP_HUMAN with the residue 1591 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069278 name: PHIP_HUMAN-Phosphoserine1592 def: "Protein PHIP_HUMAN with the residue 1592 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069279 name: PHIP_HUMAN-Phosphoserine1734 def: "Protein PHIP_HUMAN with the residue 1734 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069280 name: PHIP_HUMAN-Phosphoserine1762 def: "Protein PHIP_HUMAN with the residue 1762 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069281 name: PHIP_HUMAN-Phosphoserine1783 def: "Protein PHIP_HUMAN with the residue 1783 substituted with Phosphoserine" [UniProtKB:Q8WWQ0] xref: UniProtKB:Q8WWQ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058005 ! PHIP_HUMAN [Term] id: CCO:B0069282 name: PHLP_HUMAN-Phosphoserine18 def: "Protein PHLP_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q13371] xref: UniProtKB:Q13371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003112 ! regulator of G-protein signaling activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055903 ! PHLP_HUMAN [Term] id: CCO:B0069283 name: PHLP_HUMAN-Phosphoserine19 def: "Protein PHLP_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q13371] xref: UniProtKB:Q13371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055903 ! PHLP_HUMAN [Term] id: CCO:B0069284 name: PHLP_HUMAN-Phosphoserine20 def: "Protein PHLP_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q13371] xref: UniProtKB:Q13371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055903 ! PHLP_HUMAN [Term] id: CCO:B0069285 name: PHLP_HUMAN-Phosphoserine25 def: "Protein PHLP_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q13371] xref: UniProtKB:Q13371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055903 ! PHLP_HUMAN [Term] id: CCO:B0069286 name: PHLP_HUMAN-Phosphoserine293 def: "Protein PHLP_HUMAN with the residue 293 substituted with Phosphoserine" [UniProtKB:Q13371] xref: UniProtKB:Q13371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055903 ! PHLP_HUMAN [Term] id: CCO:B0069287 name: PHLP_HUMAN-Phosphoserine296 def: "Protein PHLP_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q13371] xref: UniProtKB:Q13371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055903 ! PHLP_HUMAN [Term] id: CCO:B0069288 name: PHOS_HUMAN-Phosphoserine73 def: "Protein PHOS_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:P20941] comment: by PKA; By similarity xref: UniProtKB:P20941 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055129 ! PHOS_HUMAN [Term] id: CCO:B0069289 name: PHP14_HUMAN-Phosphotyrosine93 def: "Protein PHP14_HUMAN with the residue 93 substituted with Phosphotyrosine" [UniProtKB:Q9NRX4] comment: By similarity xref: UniProtKB:Q9NRX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062779 ! PHP14_HUMAN [Term] id: CCO:B0069290 name: PHS_HUMAN-N-acetylalanine2 def: "Protein PHS_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P61457] xref: UniProtKB:P61457 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:B0069291 name: PI2R_HUMAN-Cysteine methyl ester383 def: "Protein PI2R_HUMAN with the residue 383 substituted with Cysteine methyl ester" [UniProtKB:P43119] xref: UniProtKB:P43119 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000141 ! rhodopsin-like receptor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001301 ! thromboxane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055360 ! PI2R_HUMAN [Term] id: CCO:B0069292 name: PI42B_HUMAN-Phosphotyrosine98 def: "Protein PI42B_HUMAN with the residue 98 substituted with Phosphotyrosine" [UniProtKB:P78356] xref: UniProtKB:P78356 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003116 ! phosphatidylinositol phosphate kinase activity relationship: has_function CCO:F0003117 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity relationship: has_function CCO:F0003118 ! 1-phosphatidylinositol-5-phosphate 4-kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055640 ! PI42B_HUMAN [Term] id: CCO:B0069293 name: PI4KA_HUMAN-Phosphoserine198 def: "Protein PI4KA_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:P42356] xref: UniProtKB:P42356 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055350 ! PI4KA_HUMAN [Term] id: CCO:B0069294 name: PI4KA_HUMAN-Phosphoserine199 def: "Protein PI4KA_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:P42356] xref: UniProtKB:P42356 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055350 ! PI4KA_HUMAN [Term] id: CCO:B0069295 name: PI4KA_HUMAN-Phosphoserine202 def: "Protein PI4KA_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:P42356] xref: UniProtKB:P42356 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055350 ! PI4KA_HUMAN [Term] id: CCO:B0069296 name: PI4KA_HUMAN-Phosphoserine204 def: "Protein PI4KA_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:P42356] xref: UniProtKB:P42356 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055350 ! PI4KA_HUMAN [Term] id: CCO:B0069297 name: PI4KA_HUMAN-Phosphoserine207 def: "Protein PI4KA_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:P42356] xref: UniProtKB:P42356 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055350 ! PI4KA_HUMAN [Term] id: CCO:B0069298 name: PI4KB_HUMAN-Phosphoserine258 def: "Protein PI4KB_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069299 name: PI4KB_HUMAN-Phosphothreonine263 def: "Protein PI4KB_HUMAN with the residue 263 substituted with Phosphothreonine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069300 name: PI4KB_HUMAN-Phosphoserine266 def: "Protein PI4KB_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069301 name: PI4KB_HUMAN-Phosphoserine277 def: "Protein PI4KB_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069302 name: PI4KB_HUMAN-Phosphoserine294 def: "Protein PI4KB_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069303 name: PI4KB_HUMAN-Phosphoserine428 def: "Protein PI4KB_HUMAN with the residue 428 substituted with Phosphoserine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069304 name: PI4KB_HUMAN-Phosphothreonine438 def: "Protein PI4KB_HUMAN with the residue 438 substituted with Phosphothreonine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069305 name: PI4KB_HUMAN-Phosphoserine511 def: "Protein PI4KB_HUMAN with the residue 511 substituted with Phosphoserine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000836 ! inositol or phosphatidylinositol kinase activity relationship: has_function CCO:F0000837 ! 1-phosphatidylinositol 4-kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001057 ! rough endoplasmic reticulum membrane relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069306 name: PI4KB_HUMAN-Phosphothreonine517 def: "Protein PI4KB_HUMAN with the residue 517 substituted with Phosphothreonine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069307 name: PI4KB_HUMAN-Phosphothreonine519 def: "Protein PI4KB_HUMAN with the residue 519 substituted with Phosphothreonine" [UniProtKB:Q9UBF8] xref: UniProtKB:Q9UBF8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:B0069308 name: PIF1_HUMAN-Phosphoserine151 def: "Protein PIF1_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q9H611] xref: UniProtKB:Q9H611 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003578 ! single-stranded DNA-dependent ATP-dependent DNA helicase activity relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_function CCO:F0005803 ! ATP-dependent 5'-3' DNA helicase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000111 ! nuclear chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058731 ! PIF1_HUMAN [Term] id: CCO:B0069309 name: PIMT_HUMAN-N-acetylalanine2 def: "Protein PIMT_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P22061] xref: UniProtKB:P22061 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001084 ! protein-L-isoaspartate (D-aspartate) O-methyltransferase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: transformation_of CCO:B0062985 ! PIMT_HUMAN [Term] id: CCO:B0069310 name: PININ_HUMAN-Phosphoserine450 def: "Protein PININ_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0069311 name: PININ_HUMAN-Phosphoserine552 def: "Protein PININ_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:Q9H307] xref: UniProtKB:Q9H307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002131 ! PININ_HUMAN [Term] id: CCO:B0069312 name: PITC1_HUMAN-Phosphoserine274 def: "Protein PITC1_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q9UKF7] comment: By similarity xref: UniProtKB:Q9UKF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059192 ! PITC1_HUMAN [Term] id: CCO:B0069313 name: PITX1_HUMAN-Phosphoserine46 def: "Protein PITX1_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:P78337] xref: UniProtKB:P78337 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055638 ! PITX1_HUMAN [Term] id: CCO:B0069314 name: PITX1_HUMAN-Phosphoserine48 def: "Protein PITX1_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:P78337] xref: UniProtKB:P78337 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055638 ! PITX1_HUMAN [Term] id: CCO:B0069315 name: PITX1_HUMAN-Phosphoserine50 def: "Protein PITX1_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:P78337] xref: UniProtKB:P78337 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055638 ! PITX1_HUMAN [Term] id: CCO:B0069316 name: PITX1_HUMAN-Phosphoserine51 def: "Protein PITX1_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:P78337] xref: UniProtKB:P78337 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055638 ! PITX1_HUMAN [Term] id: CCO:B0069317 name: PITX1_HUMAN-Phosphothreonine53 def: "Protein PITX1_HUMAN with the residue 53 substituted with Phosphothreonine" [UniProtKB:P78337] xref: UniProtKB:P78337 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055638 ! PITX1_HUMAN [Term] id: CCO:B0069318 name: PK1IP_HUMAN-Phosphoserine320 def: "Protein PK1IP_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q9NWT1] xref: UniProtKB:Q9NWT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058940 ! PK1IP_HUMAN [Term] id: CCO:B0069319 name: PK3C3_HUMAN-Phosphoserine525 def: "Protein PK3C3_HUMAN with the residue 525 substituted with Phosphoserine" [UniProtKB:Q8NEB9] comment: By similarity xref: UniProtKB:Q8NEB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057589 ! PK3C3_HUMAN [Term] id: CCO:B0069320 name: PK3CD_HUMAN-Phosphotyrosine524 def: "Protein PK3CD_HUMAN with the residue 524 substituted with Phosphotyrosine" [UniProtKB:O00329] xref: UniProtKB:O00329 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018352 ! PK3CD_HUMAN [Term] id: CCO:B0069321 name: PKCB1_HUMAN-Phosphoserine406 def: "Protein PKCB1_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069322 name: PKCB1_HUMAN-Phosphoserine460 def: "Protein PKCB1_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069323 name: PKCB1_HUMAN-Phosphoserine462 def: "Protein PKCB1_HUMAN with the residue 462 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069324 name: PKCB1_HUMAN-Phosphoserine465 def: "Protein PKCB1_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069325 name: PKCB1_HUMAN-Phosphoserine488 def: "Protein PKCB1_HUMAN with the residue 488 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069326 name: PKCB1_HUMAN-Phosphoserine495 def: "Protein PKCB1_HUMAN with the residue 495 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069327 name: PKCB1_HUMAN-Phosphothreonine541 def: "Protein PKCB1_HUMAN with the residue 541 substituted with Phosphothreonine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069328 name: PKCB1_HUMAN-Phosphoserine756 def: "Protein PKCB1_HUMAN with the residue 756 substituted with Phosphoserine" [UniProtKB:Q9ULU4] xref: UniProtKB:Q9ULU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:B0069329 name: PKD1_HUMAN-Phosphoserine4288 def: "Protein PKD1_HUMAN with the residue 4288 substituted with Phosphoserine" [UniProtKB:P98161] xref: UniProtKB:P98161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055670 ! PKD1_HUMAN [Term] id: CCO:B0069330 name: PKHA5_HUMAN-Phosphotyrosine128 def: "Protein PKHA5_HUMAN with the residue 128 substituted with Phosphotyrosine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069331 name: PKHA5_HUMAN-Phosphotyrosine134 def: "Protein PKHA5_HUMAN with the residue 134 substituted with Phosphotyrosine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069332 name: PKHA5_HUMAN-Phosphothreonine438 def: "Protein PKHA5_HUMAN with the residue 438 substituted with Phosphothreonine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069333 name: PKHA5_HUMAN-Phosphothreonine476 def: "Protein PKHA5_HUMAN with the residue 476 substituted with Phosphothreonine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069334 name: PKHA5_HUMAN-Phosphoserine568 def: "Protein PKHA5_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069335 name: PKHA5_HUMAN-Phosphoserine855 def: "Protein PKHA5_HUMAN with the residue 855 substituted with Phosphoserine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069336 name: PKHA5_HUMAN-Phosphothreonine857 def: "Protein PKHA5_HUMAN with the residue 857 substituted with Phosphothreonine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069337 name: PKHA5_HUMAN-Phosphoserine933 def: "Protein PKHA5_HUMAN with the residue 933 substituted with Phosphoserine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069338 name: PKHA5_HUMAN-Phosphoserine937 def: "Protein PKHA5_HUMAN with the residue 937 substituted with Phosphoserine" [UniProtKB:Q9HAU0] xref: UniProtKB:Q9HAU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:B0069339 name: PKHA6_HUMAN-Phosphoserine867 def: "Protein PKHA6_HUMAN with the residue 867 substituted with Phosphoserine" [UniProtKB:Q9Y2H5] xref: UniProtKB:Q9Y2H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032137 ! PKHA6_HUMAN [Term] id: CCO:B0069340 name: PKHF2_HUMAN-Phosphoserine248 def: "Protein PKHF2_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:Q9H8W4] xref: UniProtKB:Q9H8W4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005194 ! PKHF2_HUMAN [Term] id: CCO:B0069341 name: PKHG1_HUMAN-Phosphoserine1150 def: "Protein PKHG1_HUMAN with the residue 1150 substituted with Phosphoserine" [UniProtKB:Q9ULL1] xref: UniProtKB:Q9ULL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059228 ! PKHG1_HUMAN [Term] id: CCO:B0069342 name: PKHG1_HUMAN-Phosphoserine1192 def: "Protein PKHG1_HUMAN with the residue 1192 substituted with Phosphoserine" [UniProtKB:Q9ULL1] xref: UniProtKB:Q9ULL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059228 ! PKHG1_HUMAN [Term] id: CCO:B0069343 name: PKHG1_HUMAN-Phosphoserine1245 def: "Protein PKHG1_HUMAN with the residue 1245 substituted with Phosphoserine" [UniProtKB:Q9ULL1] xref: UniProtKB:Q9ULL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0059228 ! PKHG1_HUMAN [Term] id: CCO:B0069344 name: PKHG2_HUMAN-Phosphothreonine445 def: "Protein PKHG2_HUMAN with the residue 445 substituted with Phosphothreonine" [UniProtKB:Q9H7P9] xref: UniProtKB:Q9H7P9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058742 ! PKHG2_HUMAN [Term] id: CCO:B0069345 name: PKHG2_HUMAN-Phosphoserine450 def: "Protein PKHG2_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q9H7P9] xref: UniProtKB:Q9H7P9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058742 ! PKHG2_HUMAN [Term] id: CCO:B0069346 name: PKHG2_HUMAN-Phosphoserine610 def: "Protein PKHG2_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:Q9H7P9] xref: UniProtKB:Q9H7P9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058742 ! PKHG2_HUMAN [Term] id: CCO:B0069347 name: PKHG3_HUMAN-Phosphoserine76 def: "Protein PKHG3_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:A1L390] xref: UniProtKB:A1L390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053712 ! PKHG3_HUMAN [Term] id: CCO:B0069348 name: PKHG3_HUMAN-Phosphoserine640 def: "Protein PKHG3_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:A1L390] comment: By similarity xref: UniProtKB:A1L390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0053712 ! PKHG3_HUMAN [Term] id: CCO:B0069349 name: PKHG3_HUMAN-Phosphoserine643 def: "Protein PKHG3_HUMAN with the residue 643 substituted with Phosphoserine" [UniProtKB:A1L390] comment: By similarity xref: UniProtKB:A1L390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053712 ! PKHG3_HUMAN [Term] id: CCO:B0069350 name: PKHG3_HUMAN-Phosphoserine647 def: "Protein PKHG3_HUMAN with the residue 647 substituted with Phosphoserine" [UniProtKB:A1L390] comment: By similarity xref: UniProtKB:A1L390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053712 ! PKHG3_HUMAN [Term] id: CCO:B0069351 name: PKHG3_HUMAN-Phosphoserine1023 def: "Protein PKHG3_HUMAN with the residue 1023 substituted with Phosphoserine" [UniProtKB:A1L390] comment: By similarity xref: UniProtKB:A1L390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053712 ! PKHG3_HUMAN [Term] id: CCO:B0069352 name: PKHG3_HUMAN-Phosphoserine1037 def: "Protein PKHG3_HUMAN with the residue 1037 substituted with Phosphoserine" [UniProtKB:A1L390] xref: UniProtKB:A1L390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053712 ! PKHG3_HUMAN [Term] id: CCO:B0069353 name: PKHG3_HUMAN-Phosphothreonine1042 def: "Protein PKHG3_HUMAN with the residue 1042 substituted with Phosphothreonine" [UniProtKB:A1L390] xref: UniProtKB:A1L390 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053712 ! PKHG3_HUMAN [Term] id: CCO:B0069354 name: PKHG4_HUMAN-Phosphoserine64 def: "Protein PKHG4_HUMAN with the residue 64 substituted with Phosphoserine" [UniProtKB:Q58EX7] xref: UniProtKB:Q58EX7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0056375 ! PKHG4_HUMAN [Term] id: CCO:B0069355 name: PKHG5_HUMAN-Phosphoserine932 def: "Protein PKHG5_HUMAN with the residue 932 substituted with Phosphoserine" [UniProtKB:O94827] comment: By similarity xref: UniProtKB:O94827 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054702 ! PKHG5_HUMAN [Term] id: CCO:B0069356 name: PKHG5_HUMAN-Phosphoserine934 def: "Protein PKHG5_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:O94827] comment: By similarity xref: UniProtKB:O94827 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054702 ! PKHG5_HUMAN [Term] id: CCO:B0069357 name: PKHG5_HUMAN-Phosphoserine959 def: "Protein PKHG5_HUMAN with the residue 959 substituted with Phosphoserine" [UniProtKB:O94827] comment: By similarity xref: UniProtKB:O94827 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054702 ! PKHG5_HUMAN [Term] id: CCO:B0069358 name: PKHG6_HUMAN-Phosphoserine33 def: "Protein PKHG6_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:Q3KR16] comment: By similarity xref: UniProtKB:Q3KR16 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056256 ! PKHG6_HUMAN [Term] id: CCO:B0069359 name: PKHM1_HUMAN-Phosphoserine435 def: "Protein PKHM1_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:Q9Y4G2] comment: By similarity xref: UniProtKB:Q9Y4G2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059361 ! PKHM1_HUMAN [Term] id: CCO:B0069360 name: PKHM4_HUMAN-Phosphoserine473 def: "Protein PKHM4_HUMAN with the residue 473 substituted with Phosphoserine" [UniProtKB:Q69YJ1] xref: UniProtKB:Q69YJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056713 ! PKHM4_HUMAN [Term] id: CCO:B0069361 name: PKHM4_HUMAN-Phosphoserine488 def: "Protein PKHM4_HUMAN with the residue 488 substituted with Phosphoserine" [UniProtKB:Q69YJ1] xref: UniProtKB:Q69YJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056713 ! PKHM4_HUMAN [Term] id: CCO:B0069362 name: PKHM4_HUMAN-Phosphothreonine492 def: "Protein PKHM4_HUMAN with the residue 492 substituted with Phosphothreonine" [UniProtKB:Q69YJ1] xref: UniProtKB:Q69YJ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056713 ! PKHM4_HUMAN [Term] id: CCO:B0069363 name: PKN1_HUMAN-Phosphoserine533 def: "Protein PKN1_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:Q16512] xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0069364 name: PKN1_HUMAN-Phosphoserine537 def: "Protein PKN1_HUMAN with the residue 537 substituted with Phosphoserine" [UniProtKB:Q16512] xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0069365 name: PKN1_HUMAN-Phosphoserine559 def: "Protein PKN1_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:Q16512] xref: UniProtKB:Q16512 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:B0069366 name: PKN2_HUMAN-Phosphoserine110 def: "Protein PKN2_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0069367 name: PKN2_HUMAN-Phosphothreonine121 def: "Protein PKN2_HUMAN with the residue 121 substituted with Phosphothreonine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0069368 name: PKN2_HUMAN-Phosphothreonine124 def: "Protein PKN2_HUMAN with the residue 124 substituted with Phosphothreonine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0069369 name: PKN2_HUMAN-Phosphoserine362 def: "Protein PKN2_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0069370 name: PKN2_HUMAN-Phosphothreonine628 def: "Protein PKN2_HUMAN with the residue 628 substituted with Phosphothreonine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0069371 name: PKN2_HUMAN-Phosphoserine631 def: "Protein PKN2_HUMAN with the residue 631 substituted with Phosphoserine" [UniProtKB:Q16513] xref: UniProtKB:Q16513 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021020 ! PKN2_HUMAN [Term] id: CCO:B0069372 name: PKN3_HUMAN-Phosphoserine548 def: "Protein PKN3_HUMAN with the residue 548 substituted with Phosphoserine" [UniProtKB:Q6P5Z2] xref: UniProtKB:Q6P5Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021018 ! PKN3_HUMAN [Term] id: CCO:B0069373 name: PKP1_HUMAN-Phosphotyrosine214 def: "Protein PKP1_HUMAN with the residue 214 substituted with Phosphotyrosine" [UniProtKB:Q13835] xref: UniProtKB:Q13835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055947 ! PKP1_HUMAN [Term] id: CCO:B0069374 name: PKP1_HUMAN-Phosphotyrosine499 def: "Protein PKP1_HUMAN with the residue 499 substituted with Phosphotyrosine" [UniProtKB:Q13835] xref: UniProtKB:Q13835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055947 ! PKP1_HUMAN [Term] id: CCO:B0069375 name: PKP2_HUMAN-Phosphoserine151 def: "Protein PKP2_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0069376 name: PKP2_HUMAN-Phosphoserine154 def: "Protein PKP2_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0069377 name: PKP2_HUMAN-Phosphoserine155 def: "Protein PKP2_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0069378 name: PKP2_HUMAN-Phosphotyrosine168 def: "Protein PKP2_HUMAN with the residue 168 substituted with Phosphotyrosine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0069379 name: PKP2_HUMAN-Phosphoserine197 def: "Protein PKP2_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0069380 name: PKP2_HUMAN-Phosphoserine329 def: "Protein PKP2_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q99959] xref: UniProtKB:Q99959 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000463 ! intercellular junction relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000939 ! desmosome relationship: transformation_of CCO:B0005826 ! PKP2_HUMAN [Term] id: CCO:B0069381 name: PLAK_HUMAN-N-acetylmethionine1 def: "Protein PLAK_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P14923] xref: UniProtKB:P14923 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:B0069382 name: PLAK_HUMAN-Phosphotyrosine660 def: "Protein PLAK_HUMAN with the residue 660 substituted with Phosphotyrosine" [UniProtKB:P14923] xref: UniProtKB:P14923 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000465 ! cell-cell adherens junction relationship: located_in CCO:C0000468 ! fascia adherens relationship: located_in CCO:C0000703 ! internal side of plasma membrane relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000934 ! Z disc relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0000939 ! desmosome relationship: transformation_of CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:B0069383 name: PLAK_HUMAN-Phosphoserine665 def: "Protein PLAK_HUMAN with the residue 665 substituted with Phosphoserine" [UniProtKB:P14923] xref: UniProtKB:P14923 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:B0069384 name: PLCB3_HUMAN-Phosphoserine537 def: "Protein PLCB3_HUMAN with the residue 537 substituted with Phosphoserine" [UniProtKB:Q01970] xref: UniProtKB:Q01970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024484 ! PLCB3_HUMAN [Term] id: CCO:B0069385 name: PLCB3_HUMAN-Phosphoserine926 def: "Protein PLCB3_HUMAN with the residue 926 substituted with Phosphoserine" [UniProtKB:Q01970] xref: UniProtKB:Q01970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024484 ! PLCB3_HUMAN [Term] id: CCO:B0069386 name: PLCB3_HUMAN-Phosphoserine931 def: "Protein PLCB3_HUMAN with the residue 931 substituted with Phosphoserine" [UniProtKB:Q01970] xref: UniProtKB:Q01970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024484 ! PLCB3_HUMAN [Term] id: CCO:B0069387 name: PLCB3_HUMAN-Phosphoserine934 def: "Protein PLCB3_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:Q01970] xref: UniProtKB:Q01970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024484 ! PLCB3_HUMAN [Term] id: CCO:B0069388 name: PLCB3_HUMAN-Phosphothreonine1122 def: "Protein PLCB3_HUMAN with the residue 1122 substituted with Phosphothreonine" [UniProtKB:Q01970] xref: UniProtKB:Q01970 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024484 ! PLCB3_HUMAN [Term] id: CCO:B0069389 name: PLCB4_HUMAN-Phosphoserine620 def: "Protein PLCB4_HUMAN with the residue 620 substituted with Phosphoserine" [UniProtKB:Q15147] xref: UniProtKB:Q15147 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056047 ! PLCB4_HUMAN [Term] id: CCO:B0069390 name: PLCB4_HUMAN-Phosphotyrosine623 def: "Protein PLCB4_HUMAN with the residue 623 substituted with Phosphotyrosine" [UniProtKB:Q15147] xref: UniProtKB:Q15147 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056047 ! PLCB4_HUMAN [Term] id: CCO:B0069391 name: PLCB4_HUMAN-Phosphoserine890 def: "Protein PLCB4_HUMAN with the residue 890 substituted with Phosphoserine" [UniProtKB:Q15147] xref: UniProtKB:Q15147 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056047 ! PLCB4_HUMAN [Term] id: CCO:B0069392 name: PLCD3_HUMAN-Phosphoserine105 def: "Protein PLCD3_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q8N3E9] xref: UniProtKB:Q8N3E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057455 ! PLCD3_HUMAN [Term] id: CCO:B0069393 name: PLCD3_HUMAN-Phosphoserine496 def: "Protein PLCD3_HUMAN with the residue 496 substituted with Phosphoserine" [UniProtKB:Q8N3E9] xref: UniProtKB:Q8N3E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057455 ! PLCD3_HUMAN [Term] id: CCO:B0069394 name: PLCG2_HUMAN-Phosphotyrosine733 def: "Protein PLCG2_HUMAN with the residue 733 substituted with Phosphotyrosine" [UniProtKB:P16885] xref: UniProtKB:P16885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0055061 ! PLCG2_HUMAN [Term] id: CCO:B0069395 name: PLCG2_HUMAN-Phosphotyrosine753 def: "Protein PLCG2_HUMAN with the residue 753 substituted with Phosphotyrosine" [UniProtKB:P16885] xref: UniProtKB:P16885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055061 ! PLCG2_HUMAN [Term] id: CCO:B0069396 name: PLCG2_HUMAN-Phosphotyrosine759 def: "Protein PLCG2_HUMAN with the residue 759 substituted with Phosphotyrosine" [UniProtKB:P16885] xref: UniProtKB:P16885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055061 ! PLCG2_HUMAN [Term] id: CCO:B0069397 name: PLCG2_HUMAN-Phosphotyrosine1245 def: "Protein PLCG2_HUMAN with the residue 1245 substituted with Phosphotyrosine" [UniProtKB:P16885] xref: UniProtKB:P16885 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055061 ! PLCG2_HUMAN [Term] id: CCO:B0069398 name: PLCH2_HUMAN-Phosphoserine595 def: "Protein PLCH2_HUMAN with the residue 595 substituted with Phosphoserine" [UniProtKB:O75038] comment: By similarity xref: UniProtKB:O75038 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054596 ! PLCH2_HUMAN [Term] id: CCO:B0069399 name: PLCH2_HUMAN-Phosphoserine605 def: "Protein PLCH2_HUMAN with the residue 605 substituted with Phosphoserine" [UniProtKB:O75038] comment: By similarity xref: UniProtKB:O75038 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054596 ! PLCH2_HUMAN [Term] id: CCO:B0069400 name: PLCL1_HUMAN-Phosphothreonine93 def: "Protein PLCL1_HUMAN with the residue 93 substituted with Phosphothreonine" [UniProtKB:Q15111] comment: by PKA; By similarity xref: UniProtKB:Q15111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056044 ! PLCL1_HUMAN [Term] id: CCO:B0069401 name: PLCL1_HUMAN-Phosphoserine95 def: "Protein PLCL1_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q15111] comment: by PKA; By similarity xref: UniProtKB:Q15111 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000839 ! phosphoinositide phospholipase C activity relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056044 ! PLCL1_HUMAN [Term] id: CCO:B0069402 name: PLCL2_HUMAN-Phosphothreonine584 def: "Protein PLCL2_HUMAN with the residue 584 substituted with Phosphothreonine" [UniProtKB:Q9UPR0] xref: UniProtKB:Q9UPR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059265 ! PLCL2_HUMAN [Term] id: CCO:B0069403 name: PLCL2_HUMAN-Phosphoserine1113 def: "Protein PLCL2_HUMAN with the residue 1113 substituted with Phosphoserine" [UniProtKB:Q9UPR0] xref: UniProtKB:Q9UPR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059265 ! PLCL2_HUMAN [Term] id: CCO:B0069404 name: PLCX2_HUMAN-Phosphotyrosine221 def: "Protein PLCX2_HUMAN with the residue 221 substituted with Phosphotyrosine" [UniProtKB:Q0VAA5] xref: UniProtKB:Q0VAA5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001003 ! phospholipase C activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055818 ! PLCX2_HUMAN [Term] id: CCO:B0069405 name: PLEC1_HUMAN-Phosphoserine1732 def: "Protein PLEC1_HUMAN with the residue 1732 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0069406 name: PLEC1_HUMAN-Phosphotyrosine4155 def: "Protein PLEC1_HUMAN with the residue 4155 substituted with Phosphotyrosine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0069407 name: PLEC1_HUMAN-Phosphoserine4392 def: "Protein PLEC1_HUMAN with the residue 4392 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0069408 name: PLEC1_HUMAN-Phosphotyrosine4393 def: "Protein PLEC1_HUMAN with the residue 4393 substituted with Phosphotyrosine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0069409 name: PLEC1_HUMAN-Phosphothreonine4628 def: "Protein PLEC1_HUMAN with the residue 4628 substituted with Phosphothreonine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0069410 name: PLEC1_HUMAN-Phosphoserine4642 def: "Protein PLEC1_HUMAN with the residue 4642 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0069411 name: PLEC1_HUMAN-Phosphoserine4658 def: "Protein PLEC1_HUMAN with the residue 4658 substituted with Phosphoserine" [UniProtKB:Q15149] xref: UniProtKB:Q15149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050497 ! PLEC1_HUMAN [Term] id: CCO:B0069412 name: PLEK2_HUMAN-Phosphotyrosine333 def: "Protein PLEK2_HUMAN with the residue 333 substituted with Phosphotyrosine" [UniProtKB:Q9NYT0] xref: UniProtKB:Q9NYT0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0058972 ! PLEK2_HUMAN [Term] id: CCO:B0069413 name: PLEK_HUMAN-Phosphoserine113 def: "Protein PLEK_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:P08567] comment: by PKC; xref: UniProtKB:P08567 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054927 ! PLEK_HUMAN [Term] id: CCO:B0069414 name: PLEK_HUMAN-Phosphoserine117 def: "Protein PLEK_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:P08567] comment: by PKC; xref: UniProtKB:P08567 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054927 ! PLEK_HUMAN [Term] id: CCO:B0069415 name: PLEK_HUMAN-Phosphoserine183 def: "Protein PLEK_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:P08567] xref: UniProtKB:P08567 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054927 ! PLEK_HUMAN [Term] id: CCO:B0069416 name: PLEK_HUMAN-Phosphoserine197 def: "Protein PLEK_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:P08567] xref: UniProtKB:P08567 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054927 ! PLEK_HUMAN [Term] id: CCO:B0069417 name: PLK1_HUMAN-Phosphothreonine214 def: "Protein PLK1_HUMAN with the residue 214 substituted with Phosphothreonine" [UniProtKB:P53350] xref: UniProtKB:P53350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:B0069418 name: PLMN_HUMAN-Phosphoserine597 def: "Protein PLMN_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:P00747] xref: UniProtKB:P00747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054826 ! PLMN_HUMAN [Term] id: CCO:B0069419 name: PLSL_HUMAN-Phosphotyrosine28 def: "Protein PLSL_HUMAN with the residue 28 substituted with Phosphotyrosine" [UniProtKB:P13796] xref: UniProtKB:P13796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000187 ! phagocytic cup relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000442 ! actin filament relationship: transformation_of CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:B0069420 name: PLSL_HUMAN-Phosphotyrosine276 def: "Protein PLSL_HUMAN with the residue 276 substituted with Phosphotyrosine" [UniProtKB:P13796] xref: UniProtKB:P13796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:B0069421 name: PLXA1_HUMAN-Phosphotyrosine122 def: "Protein PLXA1_HUMAN with the residue 122 substituted with Phosphotyrosine" [UniProtKB:Q9UIW2] comment: By similarity xref: UniProtKB:Q9UIW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0003598 ! semaphorin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059167 ! PLXA1_HUMAN [Term] id: CCO:B0069422 name: PLXA2_HUMAN-Phosphoserine1645 def: "Protein PLXA2_HUMAN with the residue 1645 substituted with Phosphoserine" [UniProtKB:O75051] comment: By similarity xref: UniProtKB:O75051 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054599 ! PLXA2_HUMAN [Term] id: CCO:B0069423 name: PLXA2_HUMAN-Phosphoserine1648 def: "Protein PLXA2_HUMAN with the residue 1648 substituted with Phosphoserine" [UniProtKB:O75051] comment: By similarity xref: UniProtKB:O75051 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054599 ! PLXA2_HUMAN [Term] id: CCO:B0069424 name: PLXA3_HUMAN-Phosphoserine1607 def: "Protein PLXA3_HUMAN with the residue 1607 substituted with Phosphoserine" [UniProtKB:P51805] xref: UniProtKB:P51805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055480 ! PLXA3_HUMAN [Term] id: CCO:B0069425 name: PLXA3_HUMAN-Phosphoserine1610 def: "Protein PLXA3_HUMAN with the residue 1610 substituted with Phosphoserine" [UniProtKB:P51805] xref: UniProtKB:P51805 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055480 ! PLXA3_HUMAN [Term] id: CCO:B0069426 name: PLXA4_HUMAN-Phosphoserine946 def: "Protein PLXA4_HUMAN with the residue 946 substituted with Phosphoserine" [UniProtKB:Q9HCM2] xref: UniProtKB:Q9HCM2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058812 ! PLXA4_HUMAN [Term] id: CCO:B0069427 name: PLXC1_HUMAN-Phosphothreonine1466 def: "Protein PLXC1_HUMAN with the residue 1466 substituted with Phosphothreonine" [UniProtKB:O60486] xref: UniProtKB:O60486 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054561 ! PLXC1_HUMAN [Term] id: CCO:B0069428 name: PM2LB_HUMAN-Phosphotyrosine10 def: "Protein PM2LB_HUMAN with the residue 10 substituted with Phosphotyrosine" [UniProtKB:Q13670] xref: UniProtKB:Q13670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004616 ! mismatched DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0055938 ! PM2LB_HUMAN [Term] id: CCO:B0069429 name: PML_HUMAN-Phosphothreonine409 def: "Protein PML_HUMAN with the residue 409 substituted with Phosphothreonine" [UniProtKB:P29590] xref: UniProtKB:P29590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001570 ! PML_HUMAN [Term] id: CCO:B0069430 name: PNKP_HUMAN-Phosphoserine114 def: "Protein PNKP_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q96T60] xref: UniProtKB:Q96T60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003548 ! purine nucleotide binding relationship: has_function CCO:F0004124 ! nucleotide kinase activity relationship: has_function CCO:F0006176 ! polynucleotide 3'-phosphatase activity relationship: has_function CCO:F0006177 ! ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:B0069431 name: PNKP_HUMAN-Phosphothreonine118 def: "Protein PNKP_HUMAN with the residue 118 substituted with Phosphothreonine" [UniProtKB:Q96T60] xref: UniProtKB:Q96T60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:B0069432 name: PNKP_HUMAN-Phosphothreonine122 def: "Protein PNKP_HUMAN with the residue 122 substituted with Phosphothreonine" [UniProtKB:Q96T60] xref: UniProtKB:Q96T60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:B0069433 name: PNKP_HUMAN-Phosphoserine126 def: "Protein PNKP_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q96T60] xref: UniProtKB:Q96T60 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:B0069434 name: POGK_HUMAN-Phosphoserine534 def: "Protein POGK_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:Q9P215] xref: UniProtKB:Q9P215 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059049 ! POGK_HUMAN [Term] id: CCO:B0069435 name: POGZ_HUMAN-Phosphoserine333 def: "Protein POGZ_HUMAN with the residue 333 substituted with Phosphoserine" [UniProtKB:Q7Z3K3] xref: UniProtKB:Q7Z3K3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024266 ! POGZ_HUMAN [Term] id: CCO:B0069436 name: POGZ_HUMAN-Phosphoserine419 def: "Protein POGZ_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:Q7Z3K3] xref: UniProtKB:Q7Z3K3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024266 ! POGZ_HUMAN [Term] id: CCO:B0069437 name: POGZ_HUMAN-Phosphoserine425 def: "Protein POGZ_HUMAN with the residue 425 substituted with Phosphoserine" [UniProtKB:Q7Z3K3] xref: UniProtKB:Q7Z3K3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024266 ! POGZ_HUMAN [Term] id: CCO:B0069438 name: POGZ_HUMAN-Phosphoserine1338 def: "Protein POGZ_HUMAN with the residue 1338 substituted with Phosphoserine" [UniProtKB:Q7Z3K3] xref: UniProtKB:Q7Z3K3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024266 ! POGZ_HUMAN [Term] id: CCO:B0069439 name: POGZ_HUMAN-Phosphoserine1364 def: "Protein POGZ_HUMAN with the residue 1364 substituted with Phosphoserine" [UniProtKB:Q7Z3K3] xref: UniProtKB:Q7Z3K3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024266 ! POGZ_HUMAN [Term] id: CCO:B0069440 name: PP14A_HUMAN-Phosphoserine26 def: "Protein PP14A_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q96A00] xref: UniProtKB:Q96A00 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058145 ! PP14A_HUMAN [Term] id: CCO:B0069441 name: PP14A_HUMAN-Phosphothreonine38 def: "Protein PP14A_HUMAN with the residue 38 substituted with Phosphothreonine" [UniProtKB:Q96A00] comment: By similarity xref: UniProtKB:Q96A00 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058145 ! PP14A_HUMAN [Term] id: CCO:B0069442 name: PP14A_HUMAN-Phosphoserine128 def: "Protein PP14A_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:Q96A00] xref: UniProtKB:Q96A00 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058145 ! PP14A_HUMAN [Term] id: CCO:B0069443 name: PP14A_HUMAN-Phosphoserine136 def: "Protein PP14A_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q96A00] xref: UniProtKB:Q96A00 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058145 ! PP14A_HUMAN [Term] id: CCO:B0069444 name: PP14B_HUMAN-Phosphoserine32 def: "Protein PP14B_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q96C90] xref: UniProtKB:Q96C90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058179 ! PP14B_HUMAN [Term] id: CCO:B0069445 name: PP14B_HUMAN-Phosphothreonine57 def: "Protein PP14B_HUMAN with the residue 57 substituted with Phosphothreonine" [UniProtKB:Q96C90] comment: By similarity xref: UniProtKB:Q96C90 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058179 ! PP14B_HUMAN [Term] id: CCO:B0069446 name: PP14C_HUMAN-Phosphothreonine73 def: "Protein PP14C_HUMAN with the residue 73 substituted with Phosphothreonine" [UniProtKB:Q8TAE6] comment: By similarity xref: UniProtKB:Q8TAE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057886 ! PP14C_HUMAN [Term] id: CCO:B0069447 name: PP14D_HUMAN-Phosphothreonine58 def: "Protein PP14D_HUMAN with the residue 58 substituted with Phosphothreonine" [UniProtKB:Q9NXH3] xref: UniProtKB:Q9NXH3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058953 ! PP14D_HUMAN [Term] id: CCO:B0069448 name: PP1A_HUMAN-N-acetylserine2 def: "Protein PP1A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62136] xref: UniProtKB:P62136 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001688 ! PP1A_HUMAN [Term] id: CCO:B0069449 name: PP1B_HUMAN-Phosphotyrosine306 def: "Protein PP1B_HUMAN with the residue 306 substituted with Phosphotyrosine" [UniProtKB:P62140] xref: UniProtKB:P62140 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001689 ! PP1B_HUMAN [Term] id: CCO:B0069450 name: PP1B_HUMAN-Phosphothreonine316 def: "Protein PP1B_HUMAN with the residue 316 substituted with Phosphothreonine" [UniProtKB:P62140] xref: UniProtKB:P62140 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001689 ! PP1B_HUMAN [Term] id: CCO:B0069451 name: PP1G_HUMAN-Phosphothreonine307 def: "Protein PP1G_HUMAN with the residue 307 substituted with Phosphothreonine" [UniProtKB:P36873] xref: UniProtKB:P36873 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000327 ! mitochondrial outer membrane relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0001596 ! PP1G_HUMAN [Term] id: CCO:B0069452 name: PP1R8_HUMAN-Phosphoserine199 def: "Protein PP1R8_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q12972] comment: By similarity xref: UniProtKB:Q12972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:B0069453 name: PP1R8_HUMAN-Phosphoserine204 def: "Protein PP1R8_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:Q12972] comment: By similarity xref: UniProtKB:Q12972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:B0069454 name: PP1R8_HUMAN-Phosphotyrosine264 def: "Protein PP1R8_HUMAN with the residue 264 substituted with Phosphotyrosine" [UniProtKB:Q12972] comment: by LYN; in vitro; xref: UniProtKB:Q12972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001221 ! type 1 serine/threonine specific protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002327 ! ribonuclease E activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:B0069455 name: PP1R8_HUMAN-Phosphotyrosine335 def: "Protein PP1R8_HUMAN with the residue 335 substituted with Phosphotyrosine" [UniProtKB:Q12972] comment: Probable xref: UniProtKB:Q12972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:B0069456 name: PP2BA_HUMAN-Phosphoserine469 def: "Protein PP2BA_HUMAN with the residue 469 substituted with Phosphoserine" [UniProtKB:Q08209] comment: By similarity xref: UniProtKB:Q08209 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016306 ! PP2BA_HUMAN [Term] id: CCO:B0069457 name: PPLA_HUMAN-N-acetylmethionine1 def: "Protein PPLA_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P26678] comment: By similarity xref: UniProtKB:P26678 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063298 ! PPLA_HUMAN [Term] id: CCO:B0069458 name: PPLA_HUMAN-Phosphoserine16 def: "Protein PPLA_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:P26678] comment: by PKA; By similarity xref: UniProtKB:P26678 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063298 ! PPLA_HUMAN [Term] id: CCO:B0069459 name: PPLA_HUMAN-Phosphothreonine17 def: "Protein PPLA_HUMAN with the residue 17 substituted with Phosphothreonine" [UniProtKB:P26678] comment: by CaMK; By similarity xref: UniProtKB:P26678 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063298 ! PPLA_HUMAN [Term] id: CCO:B0069460 name: PPR1A_HUMAN-Phosphothreonine35 def: "Protein PPR1A_HUMAN with the residue 35 substituted with Phosphothreonine" [UniProtKB:Q13522] comment: by PKA; xref: UniProtKB:Q13522 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_function CCO:F0001221 ! type 1 serine/threonine specific protein phosphatase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055924 ! PPR1A_HUMAN [Term] id: CCO:B0069461 name: PPR1B_HUMAN-N-acetylmethionine1 def: "Protein PPR1B_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q9UD71] comment: By similarity xref: UniProtKB:Q9UD71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059099 ! PPR1B_HUMAN [Term] id: CCO:B0069462 name: PPR1B_HUMAN-Phosphothreonine34 def: "Protein PPR1B_HUMAN with the residue 34 substituted with Phosphothreonine" [UniProtKB:Q9UD71] comment: by PKA; By similarity xref: UniProtKB:Q9UD71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059099 ! PPR1B_HUMAN [Term] id: CCO:B0069463 name: PPR1B_HUMAN-Phosphothreonine75 def: "Protein PPR1B_HUMAN with the residue 75 substituted with Phosphothreonine" [UniProtKB:Q9UD71] comment: by CDK5; xref: UniProtKB:Q9UD71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001220 ! protein phosphatase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059099 ! PPR1B_HUMAN [Term] id: CCO:B0069464 name: PPR1B_HUMAN-Phosphoserine198 def: "Protein PPR1B_HUMAN with the residue 198 substituted with Phosphoserine" [UniProtKB:Q9UD71] comment: By similarity xref: UniProtKB:Q9UD71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059099 ! PPR1B_HUMAN [Term] id: CCO:B0069465 name: PR285_HUMAN-Phosphoserine1006 def: "Protein PR285_HUMAN with the residue 1006 substituted with Phosphoserine" [UniProtKB:Q9BYK8] xref: UniProtKB:Q9BYK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006035 ! PR285_HUMAN [Term] id: CCO:B0069466 name: PR38A_HUMAN-Phosphoserine182 def: "Protein PR38A_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q8NAV1] comment: By similarity xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069467 name: PR38A_HUMAN-Phosphoserine193 def: "Protein PR38A_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069468 name: PR38A_HUMAN-Phosphoserine194 def: "Protein PR38A_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069469 name: PR38A_HUMAN-Phosphoserine209 def: "Protein PR38A_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069470 name: PR38A_HUMAN-Phosphoserine226 def: "Protein PR38A_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069471 name: PR38A_HUMAN-Phosphothreonine228 def: "Protein PR38A_HUMAN with the residue 228 substituted with Phosphothreonine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069472 name: PR38A_HUMAN-Phosphoserine260 def: "Protein PR38A_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069473 name: PR38A_HUMAN-Phosphoserine262 def: "Protein PR38A_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069474 name: PR38A_HUMAN-Phosphoserine279 def: "Protein PR38A_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069475 name: PR38A_HUMAN-Phosphoserine281 def: "Protein PR38A_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q8NAV1] xref: UniProtKB:Q8NAV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:B0069476 name: PR40A_HUMAN-Phosphoserine34 def: "Protein PR40A_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069477 name: PR40A_HUMAN-Phosphoserine36 def: "Protein PR40A_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:O75400] comment: By similarity xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069478 name: PR40A_HUMAN-Phosphothreonine373 def: "Protein PR40A_HUMAN with the residue 373 substituted with Phosphothreonine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069479 name: PR40A_HUMAN-Phosphoserine883 def: "Protein PR40A_HUMAN with the residue 883 substituted with Phosphoserine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069480 name: PR40A_HUMAN-Phosphoserine885 def: "Protein PR40A_HUMAN with the residue 885 substituted with Phosphoserine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069481 name: PR40A_HUMAN-Phosphoserine888 def: "Protein PR40A_HUMAN with the residue 888 substituted with Phosphoserine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069482 name: PR40A_HUMAN-Phosphothreonine932 def: "Protein PR40A_HUMAN with the residue 932 substituted with Phosphothreonine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069483 name: PR40A_HUMAN-Phosphoserine933 def: "Protein PR40A_HUMAN with the residue 933 substituted with Phosphoserine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069484 name: PR40A_HUMAN-Phosphoserine935 def: "Protein PR40A_HUMAN with the residue 935 substituted with Phosphoserine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069485 name: PR40A_HUMAN-Phosphoserine938 def: "Protein PR40A_HUMAN with the residue 938 substituted with Phosphoserine" [UniProtKB:O75400] xref: UniProtKB:O75400 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:B0069486 name: PRAM_HUMAN-Phosphoserine382 def: "Protein PRAM_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:Q96QH2] comment: By similarity xref: UniProtKB:Q96QH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001816 ! lipid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058353 ! PRAM_HUMAN [Term] id: CCO:B0069487 name: PRD10_HUMAN-Phosphoserine338 def: "Protein PRD10_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:Q9NQV6] xref: UniProtKB:Q9NQV6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058873 ! PRD10_HUMAN [Term] id: CCO:B0069488 name: PRD10_HUMAN-Phosphothreonine342 def: "Protein PRD10_HUMAN with the residue 342 substituted with Phosphothreonine" [UniProtKB:Q9NQV6] xref: UniProtKB:Q9NQV6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058873 ! PRD10_HUMAN [Term] id: CCO:B0069489 name: PRD10_HUMAN-Phosphoserine1002 def: "Protein PRD10_HUMAN with the residue 1002 substituted with Phosphoserine" [UniProtKB:Q9NQV6] xref: UniProtKB:Q9NQV6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058873 ! PRD10_HUMAN [Term] id: CCO:B0069490 name: PRDM2_HUMAN-Phosphothreonine641 def: "Protein PRDM2_HUMAN with the residue 641 substituted with Phosphothreonine" [UniProtKB:Q13029] xref: UniProtKB:Q13029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055868 ! PRDM2_HUMAN [Term] id: CCO:B0069491 name: PRDM2_HUMAN-Phosphoserine643 def: "Protein PRDM2_HUMAN with the residue 643 substituted with Phosphoserine" [UniProtKB:Q13029] xref: UniProtKB:Q13029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055868 ! PRDM2_HUMAN [Term] id: CCO:B0069492 name: PRDM2_HUMAN-Phosphoserine739 def: "Protein PRDM2_HUMAN with the residue 739 substituted with Phosphoserine" [UniProtKB:Q13029] xref: UniProtKB:Q13029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055868 ! PRDM2_HUMAN [Term] id: CCO:B0069493 name: PRDM2_HUMAN-Phosphoserine743 def: "Protein PRDM2_HUMAN with the residue 743 substituted with Phosphoserine" [UniProtKB:Q13029] xref: UniProtKB:Q13029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055868 ! PRDM2_HUMAN [Term] id: CCO:B0069494 name: PRDX1_HUMAN-Phosphothreonine90 def: "Protein PRDX1_HUMAN with the residue 90 substituted with Phosphothreonine" [UniProtKB:Q06830] comment: by CDC2; xref: UniProtKB:Q06830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055775 ! PRDX1_HUMAN [Term] id: CCO:B0069495 name: PRDX1_HUMAN-Phosphothreonine183 def: "Protein PRDX1_HUMAN with the residue 183 substituted with Phosphothreonine" [UniProtKB:Q06830] xref: UniProtKB:Q06830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055775 ! PRDX1_HUMAN [Term] id: CCO:B0069496 name: PRDX1_HUMAN-Phosphotyrosine194 def: "Protein PRDX1_HUMAN with the residue 194 substituted with Phosphotyrosine" [UniProtKB:Q06830] xref: UniProtKB:Q06830 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055775 ! PRDX1_HUMAN [Term] id: CCO:B0069497 name: PRDX2_HUMAN-N-acetylalanine2 def: "Protein PRDX2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P32119] comment: By similarity xref: UniProtKB:P32119 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055249 ! PRDX2_HUMAN [Term] id: CCO:B0069498 name: PRG4_HUMAN-Phosphothreonine540 def: "Protein PRG4_HUMAN with the residue 540 substituted with Phosphothreonine" [UniProtKB:Q92954] xref: UniProtKB:Q92954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058115 ! PRG4_HUMAN [Term] id: CCO:B0069499 name: PRGC2_HUMAN-Phosphoserine524 def: "Protein PRGC2_HUMAN with the residue 524 substituted with Phosphoserine" [UniProtKB:Q86YN6] xref: UniProtKB:Q86YN6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0004390 ! estrogen receptor binding relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0004458 ! receptor activator activity relationship: has_function CCO:F0007991 ! AF-2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057308 ! PRGC2_HUMAN [Term] id: CCO:B0069500 name: PRGR_HUMAN-Phosphoserine20 def: "Protein PRGR_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069501 name: PRGR_HUMAN-Phosphoserine25 def: "Protein PRGR_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:P06401] comment: by CDK2; in vitro; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069502 name: PRGR_HUMAN-Phosphothreonine41 def: "Protein PRGR_HUMAN with the residue 41 substituted with Phosphothreonine" [UniProtKB:P06401] comment: by CK; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069503 name: PRGR_HUMAN-Phosphoserine102 def: "Protein PRGR_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001634 ! steroid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069504 name: PRGR_HUMAN-Phosphoserine130 def: "Protein PRGR_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069505 name: PRGR_HUMAN-Phosphoserine162 def: "Protein PRGR_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069506 name: PRGR_HUMAN-Phosphoserine190 def: "Protein PRGR_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069507 name: PRGR_HUMAN-Phosphoserine213 def: "Protein PRGR_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069508 name: PRGR_HUMAN-Phosphoserine227 def: "Protein PRGR_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:P06401] comment: by CK; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069509 name: PRGR_HUMAN-Phosphoserine232 def: "Protein PRGR_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:P06401] comment: by CK; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069510 name: PRGR_HUMAN-Phosphoserine345 def: "Protein PRGR_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069511 name: PRGR_HUMAN-Phosphothreonine430 def: "Protein PRGR_HUMAN with the residue 430 substituted with Phosphothreonine" [UniProtKB:P06401] comment: by CDK2; in vitro; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069512 name: PRGR_HUMAN-Phosphoserine552 def: "Protein PRGR_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:P06401] comment: by CK; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069513 name: PRGR_HUMAN-Phosphoserine554 def: "Protein PRGR_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:P06401] comment: by CDK2; in vitro; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069514 name: PRGR_HUMAN-Phosphoserine676 def: "Protein PRGR_HUMAN with the residue 676 substituted with Phosphoserine" [UniProtKB:P06401] xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069515 name: PRGR_HUMAN-Phosphoserine793 def: "Protein PRGR_HUMAN with the residue 793 substituted with Phosphoserine" [UniProtKB:P06401] comment: by CK; xref: UniProtKB:P06401 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:B0069516 name: PRKDC_HUMAN-Phosphoserine893 def: "Protein PRKDC_HUMAN with the residue 893 substituted with Phosphoserine" [UniProtKB:P78527] xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069517 name: PRKDC_HUMAN-Phosphothreonine2603 def: "Protein PRKDC_HUMAN with the residue 2603 substituted with Phosphothreonine" [UniProtKB:P78527] xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069518 name: PRKDC_HUMAN-Phosphothreonine2609 def: "Protein PRKDC_HUMAN with the residue 2609 substituted with Phosphothreonine" [UniProtKB:P78527] comment: by autocatalysis; xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069519 name: PRKDC_HUMAN-Phosphoserine2612 def: "Protein PRKDC_HUMAN with the residue 2612 substituted with Phosphoserine" [UniProtKB:P78527] comment: by autocatalysis; xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069520 name: PRKDC_HUMAN-Phosphothreonine2638 def: "Protein PRKDC_HUMAN with the residue 2638 substituted with Phosphothreonine" [UniProtKB:P78527] comment: by autocatalysis; xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069521 name: PRKDC_HUMAN-Phosphothreonine2647 def: "Protein PRKDC_HUMAN with the residue 2647 substituted with Phosphothreonine" [UniProtKB:P78527] comment: by autocatalysis; xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069522 name: PRKDC_HUMAN-Phosphothreonine2649 def: "Protein PRKDC_HUMAN with the residue 2649 substituted with Phosphothreonine" [UniProtKB:P78527] xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069523 name: PRKDC_HUMAN-Phosphotyrosine2743 def: "Protein PRKDC_HUMAN with the residue 2743 substituted with Phosphotyrosine" [UniProtKB:P78527] xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069524 name: PRKDC_HUMAN-Phosphoserine3205 def: "Protein PRKDC_HUMAN with the residue 3205 substituted with Phosphoserine" [UniProtKB:P78527] xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069525 name: PRKDC_HUMAN-Phosphoserine4026 def: "Protein PRKDC_HUMAN with the residue 4026 substituted with Phosphoserine" [UniProtKB:P78527] xref: UniProtKB:P78527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001048 ! DNA-dependent protein kinase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000506 ! DNA-dependent protein kinase complex relationship: transformation_of CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:B0069526 name: PRKRA_HUMAN-Phosphoserine18 def: "Protein PRKRA_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:O75569] xref: UniProtKB:O75569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054651 ! PRKRA_HUMAN [Term] id: CCO:B0069527 name: PROC_HUMAN-4-carboxyglutamate48 def: "Protein PROC_HUMAN with the residue 48 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069528 name: PROC_HUMAN-4-carboxyglutamate49 def: "Protein PROC_HUMAN with the residue 49 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069529 name: PROC_HUMAN-4-carboxyglutamate56 def: "Protein PROC_HUMAN with the residue 56 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069530 name: PROC_HUMAN-4-carboxyglutamate58 def: "Protein PROC_HUMAN with the residue 58 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069531 name: PROC_HUMAN-4-carboxyglutamate61 def: "Protein PROC_HUMAN with the residue 61 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069532 name: PROC_HUMAN-4-carboxyglutamate62 def: "Protein PROC_HUMAN with the residue 62 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069533 name: PROC_HUMAN-4-carboxyglutamate67 def: "Protein PROC_HUMAN with the residue 67 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069534 name: PROC_HUMAN-4-carboxyglutamate68 def: "Protein PROC_HUMAN with the residue 68 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069535 name: PROC_HUMAN-4-carboxyglutamate71 def: "Protein PROC_HUMAN with the residue 71 substituted with 4-carboxyglutamate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069536 name: PROC_HUMAN-3-hydroxyaspartate113 def: "Protein PROC_HUMAN with the residue 113 substituted with 3-hydroxyaspartate" [UniProtKB:P04070] xref: UniProtKB:P04070 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054884 ! PROC_HUMAN [Term] id: CCO:B0069537 name: PROX1_HUMAN-Phosphoserine177 def: "Protein PROX1_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:Q92786] comment: By similarity xref: UniProtKB:Q92786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058095 ! PROX1_HUMAN [Term] id: CCO:B0069538 name: PROX1_HUMAN-Phosphoserine179 def: "Protein PROX1_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q92786] comment: By similarity xref: UniProtKB:Q92786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058095 ! PROX1_HUMAN [Term] id: CCO:B0069539 name: PROX1_HUMAN-Phosphoserine291 def: "Protein PROX1_HUMAN with the residue 291 substituted with Phosphoserine" [UniProtKB:Q92786] comment: By similarity xref: UniProtKB:Q92786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058095 ! PROX1_HUMAN [Term] id: CCO:B0069540 name: PROX1_HUMAN-Phosphoserine511 def: "Protein PROX1_HUMAN with the residue 511 substituted with Phosphoserine" [UniProtKB:Q92786] comment: By similarity xref: UniProtKB:Q92786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058095 ! PROX1_HUMAN [Term] id: CCO:B0069541 name: PROX1_HUMAN-Phosphoserine514 def: "Protein PROX1_HUMAN with the residue 514 substituted with Phosphoserine" [UniProtKB:Q92786] comment: By similarity xref: UniProtKB:Q92786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058095 ! PROX1_HUMAN [Term] id: CCO:B0069542 name: PROX1_HUMAN-Phosphothreonine650 def: "Protein PROX1_HUMAN with the residue 650 substituted with Phosphothreonine" [UniProtKB:Q92786] comment: By similarity xref: UniProtKB:Q92786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058095 ! PROX1_HUMAN [Term] id: CCO:B0069543 name: PRP19_HUMAN-Phosphoserine307 def: "Protein PRP19_HUMAN with the residue 307 substituted with Phosphoserine" [UniProtKB:Q9UMS4] xref: UniProtKB:Q9UMS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016149 ! PRP19_HUMAN [Term] id: CCO:B0069544 name: PRP19_HUMAN-Phosphothreonine310 def: "Protein PRP19_HUMAN with the residue 310 substituted with Phosphothreonine" [UniProtKB:Q9UMS4] xref: UniProtKB:Q9UMS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016149 ! PRP19_HUMAN [Term] id: CCO:B0069545 name: PRP19_HUMAN-Phosphoserine313 def: "Protein PRP19_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q9UMS4] xref: UniProtKB:Q9UMS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016149 ! PRP19_HUMAN [Term] id: CCO:B0069546 name: PRP19_HUMAN-Phosphotyrosine329 def: "Protein PRP19_HUMAN with the residue 329 substituted with Phosphotyrosine" [UniProtKB:Q9UMS4] xref: UniProtKB:Q9UMS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016149 ! PRP19_HUMAN [Term] id: CCO:B0069547 name: PRP19_HUMAN-Phosphothreonine342 def: "Protein PRP19_HUMAN with the residue 342 substituted with Phosphothreonine" [UniProtKB:Q9UMS4] xref: UniProtKB:Q9UMS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000382 ! lipid particle relationship: transformation_of CCO:B0016149 ! PRP19_HUMAN [Term] id: CCO:B0069548 name: PRP4B_HUMAN-Phosphotyrosine140 def: "Protein PRP4B_HUMAN with the residue 140 substituted with Phosphotyrosine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0069549 name: PRP4B_HUMAN-Phosphoserine142 def: "Protein PRP4B_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0069550 name: PRP4B_HUMAN-Phosphoserine144 def: "Protein PRP4B_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0069551 name: PRP4B_HUMAN-Phosphoserine518 def: "Protein PRP4B_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0069552 name: PRP4B_HUMAN-Phosphoserine519 def: "Protein PRP4B_HUMAN with the residue 519 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0069553 name: PRP4B_HUMAN-Phosphoserine520 def: "Protein PRP4B_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:Q13523] xref: UniProtKB:Q13523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:B0069554 name: PRP8_HUMAN-Phosphoserine1539 def: "Protein PRP8_HUMAN with the residue 1539 substituted with Phosphoserine" [UniProtKB:Q6P2Q9] xref: UniProtKB:Q6P2Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020752 ! PRP8_HUMAN [Term] id: CCO:B0069555 name: PRP8_HUMAN-Phosphoserine2079 def: "Protein PRP8_HUMAN with the residue 2079 substituted with Phosphoserine" [UniProtKB:Q6P2Q9] xref: UniProtKB:Q6P2Q9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020752 ! PRP8_HUMAN [Term] id: CCO:B0069556 name: PRPF3_HUMAN-Phosphoserine133 def: "Protein PRPF3_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:O43395] xref: UniProtKB:O43395 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062912 ! PRPF3_HUMAN [Term] id: CCO:B0069557 name: PRPF3_HUMAN-Phosphoserine356 def: "Protein PRPF3_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:O43395] xref: UniProtKB:O43395 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062912 ! PRPF3_HUMAN [Term] id: CCO:B0069558 name: PRPF3_HUMAN-Phosphoserine619 def: "Protein PRPF3_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:O43395] xref: UniProtKB:O43395 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0062912 ! PRPF3_HUMAN [Term] id: CCO:B0069559 name: PRRX1_HUMAN-Phosphoserine197 def: "Protein PRRX1_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:P54821] comment: Potential xref: UniProtKB:P54821 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055517 ! PRRX1_HUMAN [Term] id: CCO:B0069560 name: PRS10_HUMAN-Phosphotyrosine207 def: "Protein PRS10_HUMAN with the residue 207 substituted with Phosphotyrosine" [UniProtKB:P62333] xref: UniProtKB:P62333 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030905 ! PRS10_HUMAN [Term] id: CCO:B0069561 name: PRS6B_HUMAN-Phosphoserine28 def: "Protein PRS6B_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:P43686] xref: UniProtKB:P43686 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041247 ! PRS6B_HUMAN [Term] id: CCO:B0069562 name: PSA2_HUMAN-Phosphotyrosine57 def: "Protein PSA2_HUMAN with the residue 57 substituted with Phosphotyrosine" [UniProtKB:P25787] xref: UniProtKB:P25787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:B0069563 name: PSA6_HUMAN-Phosphotyrosine160 def: "Protein PSA6_HUMAN with the residue 160 substituted with Phosphotyrosine" [UniProtKB:P60900] xref: UniProtKB:P60900 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:B0069564 name: PSD1_HUMAN-Phosphoserine720 def: "Protein PSD1_HUMAN with the residue 720 substituted with Phosphoserine" [UniProtKB:A5PKW4] comment: By similarity xref: UniProtKB:A5PKW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053775 ! PSD1_HUMAN [Term] id: CCO:B0069565 name: PSD3_HUMAN-Phosphoserine770 def: "Protein PSD3_HUMAN with the residue 770 substituted with Phosphoserine" [UniProtKB:Q9NYI0] xref: UniProtKB:Q9NYI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058963 ! PSD3_HUMAN [Term] id: CCO:B0069566 name: PSD3_HUMAN-Phosphoserine1011 def: "Protein PSD3_HUMAN with the residue 1011 substituted with Phosphoserine" [UniProtKB:Q9NYI0] xref: UniProtKB:Q9NYI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001391 ! ARF guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0058963 ! PSD3_HUMAN [Term] id: CCO:B0069567 name: PSD3_HUMAN-Phosphoserine1012 def: "Protein PSD3_HUMAN with the residue 1012 substituted with Phosphoserine" [UniProtKB:Q9NYI0] comment: By similarity xref: UniProtKB:Q9NYI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058963 ! PSD3_HUMAN [Term] id: CCO:B0069568 name: PSD3_HUMAN-Phosphoserine1020 def: "Protein PSD3_HUMAN with the residue 1020 substituted with Phosphoserine" [UniProtKB:Q9NYI0] xref: UniProtKB:Q9NYI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058963 ! PSD3_HUMAN [Term] id: CCO:B0069569 name: PSIP1_HUMAN-Phosphoserine106 def: "Protein PSIP1_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:O75475] xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069570 name: PSIP1_HUMAN-Phosphothreonine122 def: "Protein PSIP1_HUMAN with the residue 122 substituted with Phosphothreonine" [UniProtKB:O75475] xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069571 name: PSIP1_HUMAN-Phosphoserine129 def: "Protein PSIP1_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:O75475] xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069572 name: PSIP1_HUMAN-Phosphothreonine134 def: "Protein PSIP1_HUMAN with the residue 134 substituted with Phosphothreonine" [UniProtKB:O75475] comment: By similarity xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069573 name: PSIP1_HUMAN-Phosphothreonine141 def: "Protein PSIP1_HUMAN with the residue 141 substituted with Phosphothreonine" [UniProtKB:O75475] xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069574 name: PSIP1_HUMAN-Phosphoserine177 def: "Protein PSIP1_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:O75475] comment: By similarity xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069575 name: PSIP1_HUMAN-Phosphoserine273 def: "Protein PSIP1_HUMAN with the residue 273 substituted with Phosphoserine" [UniProtKB:O75475] xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069576 name: PSIP1_HUMAN-Phosphoserine275 def: "Protein PSIP1_HUMAN with the residue 275 substituted with Phosphoserine" [UniProtKB:O75475] xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069577 name: PSIP1_HUMAN-Phosphothreonine437 def: "Protein PSIP1_HUMAN with the residue 437 substituted with Phosphothreonine" [UniProtKB:O75475] xref: UniProtKB:O75475 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054642 ! PSIP1_HUMAN [Term] id: CCO:B0069578 name: PSMD1_HUMAN-Phosphoserine296 def: "Protein PSMD1_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q99460] xref: UniProtKB:Q99460 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002066 ! PSMD1_HUMAN [Term] id: CCO:B0069579 name: PSMF1_HUMAN-Phosphoserine252 def: "Protein PSMF1_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:Q92530] xref: UniProtKB:Q92530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001987 ! proteasome inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: located_in CCO:C0002080 ! proteasome core complex relationship: transformation_of CCO:B0041263 ! PSMF1_HUMAN [Term] id: CCO:B0069580 name: PSPC1_HUMAN-Phosphoserine509 def: "Protein PSPC1_HUMAN with the residue 509 substituted with Phosphoserine" [UniProtKB:Q8WXF1] xref: UniProtKB:Q8WXF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058017 ! PSPC1_HUMAN [Term] id: CCO:B0069581 name: PSRC1_HUMAN-Phosphoserine137 def: "Protein PSRC1_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0069582 name: PSRC1_HUMAN-Phosphoserine142 def: "Protein PSRC1_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0069583 name: PSRC1_HUMAN-Phosphothreonine145 def: "Protein PSRC1_HUMAN with the residue 145 substituted with Phosphothreonine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0069584 name: PSRC1_HUMAN-Phosphoserine186 def: "Protein PSRC1_HUMAN with the residue 186 substituted with Phosphoserine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0069585 name: PSRC1_HUMAN-Phosphoserine190 def: "Protein PSRC1_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q6PGN9] xref: UniProtKB:Q6PGN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043829 ! PSRC1_HUMAN [Term] id: CCO:B0069586 name: PSYR_HUMAN-Phosphotyrosine113 def: "Protein PSYR_HUMAN with the residue 113 substituted with Phosphotyrosine" [UniProtKB:Q8IYL9] xref: UniProtKB:Q8IYL9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024306 ! PSYR_HUMAN [Term] id: CCO:B0069587 name: PTAD1_HUMAN-Phosphoserine114 def: "Protein PTAD1_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q9P035] xref: UniProtKB:Q9P035 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059026 ! PTAD1_HUMAN [Term] id: CCO:B0069588 name: PTBP1_HUMAN-Phosphotyrosine127 def: "Protein PTBP1_HUMAN with the residue 127 substituted with Phosphotyrosine" [UniProtKB:P26599] xref: UniProtKB:P26599 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037269 ! PTBP1_HUMAN [Term] id: CCO:B0069589 name: PTN11_HUMAN-Phosphotyrosine62 def: "Protein PTN11_HUMAN with the residue 62 substituted with Phosphotyrosine" [UniProtKB:Q06124] xref: UniProtKB:Q06124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:B0069590 name: PTN11_HUMAN-Phosphotyrosine63 def: "Protein PTN11_HUMAN with the residue 63 substituted with Phosphotyrosine" [UniProtKB:Q06124] xref: UniProtKB:Q06124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:B0069591 name: PTN11_HUMAN-Phosphotyrosine66 def: "Protein PTN11_HUMAN with the residue 66 substituted with Phosphotyrosine" [UniProtKB:Q06124] comment: By similarity xref: UniProtKB:Q06124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:B0069592 name: PTN11_HUMAN-Phosphotyrosine546 def: "Protein PTN11_HUMAN with the residue 546 substituted with Phosphotyrosine" [UniProtKB:Q06124] comment: by PDGFR; xref: UniProtKB:Q06124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:B0069593 name: PTN11_HUMAN-Phosphotyrosine584 def: "Protein PTN11_HUMAN with the residue 584 substituted with Phosphotyrosine" [UniProtKB:Q06124] comment: by PDGFR; xref: UniProtKB:Q06124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:B0069594 name: PTN11_HUMAN-Phosphoserine595 def: "Protein PTN11_HUMAN with the residue 595 substituted with Phosphoserine" [UniProtKB:Q06124] xref: UniProtKB:Q06124 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:B0069595 name: PTN1_HUMAN-N-acetylmethionine1 def: "Protein PTN1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P18031] xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069596 name: PTN1_HUMAN-Phosphotyrosine20 def: "Protein PTN1_HUMAN with the residue 20 substituted with Phosphotyrosine" [UniProtKB:P18031] xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069597 name: PTN1_HUMAN-Phosphoserine50 def: "Protein PTN1_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:P18031] comment: by PKB/AKT1; xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069598 name: PTN1_HUMAN-Phosphoserine295 def: "Protein PTN1_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:P18031] xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069599 name: PTN1_HUMAN-Phosphoserine352 def: "Protein PTN1_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:P18031] xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069600 name: PTN1_HUMAN-Phosphoserine378 def: "Protein PTN1_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:P18031] comment: by PKC; xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069601 name: PTN1_HUMAN-Phosphoserine386 def: "Protein PTN1_HUMAN with the residue 386 substituted with Phosphoserine" [UniProtKB:P18031] comment: by CDC2; xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001090 ! protein tyrosine phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069602 name: PTN1_HUMAN-Phosphoserine393 def: "Protein PTN1_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:P18031] comment: By similarity xref: UniProtKB:P18031 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:B0069603 name: PTN6_HUMAN-Phosphotyrosine564 def: "Protein PTN6_HUMAN with the residue 564 substituted with Phosphotyrosine" [UniProtKB:P29350] xref: UniProtKB:P29350 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005608 ! PTN6_HUMAN [Term] id: CCO:B0069604 name: PTPRG_HUMAN-Phosphothreonine115 def: "Protein PTPRG_HUMAN with the residue 115 substituted with Phosphothreonine" [UniProtKB:P23470] comment: By similarity xref: UniProtKB:P23470 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055158 ! PTPRG_HUMAN [Term] id: CCO:B0069605 name: PTRF_HUMAN-N-acetylmethionine1 def: "Protein PTRF_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000303 ! RNA polymerase I transcription termination factor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_function CCO:F0005627 ! rRNA primary transcript binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069606 name: PTRF_HUMAN-Phosphoserine36 def: "Protein PTRF_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069607 name: PTRF_HUMAN-Phosphoserine40 def: "Protein PTRF_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069608 name: PTRF_HUMAN-Phosphotyrosine156 def: "Protein PTRF_HUMAN with the residue 156 substituted with Phosphotyrosine" [UniProtKB:Q6NZI2] comment: By similarity xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069609 name: PTRF_HUMAN-Phosphoserine167 def: "Protein PTRF_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069610 name: PTRF_HUMAN-Phosphoserine202 def: "Protein PTRF_HUMAN with the residue 202 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069611 name: PTRF_HUMAN-Phosphoserine203 def: "Protein PTRF_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069612 name: PTRF_HUMAN-Phosphoserine300 def: "Protein PTRF_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069613 name: PTRF_HUMAN-Phosphothreonine302 def: "Protein PTRF_HUMAN with the residue 302 substituted with Phosphothreonine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069614 name: PTRF_HUMAN-Phosphotyrosine308 def: "Protein PTRF_HUMAN with the residue 308 substituted with Phosphotyrosine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069615 name: PTRF_HUMAN-Phosphoserine365 def: "Protein PTRF_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069616 name: PTRF_HUMAN-Phosphoserine366 def: "Protein PTRF_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069617 name: PTRF_HUMAN-Phosphothreonine376 def: "Protein PTRF_HUMAN with the residue 376 substituted with Phosphothreonine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069618 name: PTRF_HUMAN-Phosphoserine379 def: "Protein PTRF_HUMAN with the residue 379 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069619 name: PTRF_HUMAN-Phosphoserine387 def: "Protein PTRF_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069620 name: PTRF_HUMAN-Phosphoserine389 def: "Protein PTRF_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:Q6NZI2] xref: UniProtKB:Q6NZI2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056873 ! PTRF_HUMAN [Term] id: CCO:B0069621 name: PUF60_HUMAN-Phosphothreonine60 def: "Protein PUF60_HUMAN with the residue 60 substituted with Phosphothreonine" [UniProtKB:Q9UHX1] xref: UniProtKB:Q9UHX1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000901 ! cyclin-dependent protein kinase activating kinase holoenzyme complex relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0059151 ! PUF60_HUMAN [Term] id: CCO:B0069622 name: PUF60_HUMAN-Phosphoserine206 def: "Protein PUF60_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q9UHX1] xref: UniProtKB:Q9UHX1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059151 ! PUF60_HUMAN [Term] id: CCO:B0069623 name: PUM1_HUMAN-Phosphoserine19 def: "Protein PUM1_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q14671] xref: UniProtKB:Q14671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024392 ! PUM1_HUMAN [Term] id: CCO:B0069624 name: PUM1_HUMAN-Phosphoserine75 def: "Protein PUM1_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q14671] xref: UniProtKB:Q14671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0024392 ! PUM1_HUMAN [Term] id: CCO:B0069625 name: PUM1_HUMAN-Phosphoserine209 def: "Protein PUM1_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:Q14671] xref: UniProtKB:Q14671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024392 ! PUM1_HUMAN [Term] id: CCO:B0069626 name: PUM1_HUMAN-Phosphoserine709 def: "Protein PUM1_HUMAN with the residue 709 substituted with Phosphoserine" [UniProtKB:Q14671] xref: UniProtKB:Q14671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024392 ! PUM1_HUMAN [Term] id: CCO:B0069627 name: PUM1_HUMAN-Phosphoserine714 def: "Protein PUM1_HUMAN with the residue 714 substituted with Phosphoserine" [UniProtKB:Q14671] xref: UniProtKB:Q14671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024392 ! PUM1_HUMAN [Term] id: CCO:B0069628 name: PUM2_HUMAN-Phosphoserine82 def: "Protein PUM2_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q8TB72] xref: UniProtKB:Q8TB72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:B0069629 name: PUM2_HUMAN-Phosphoserine136 def: "Protein PUM2_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q8TB72] xref: UniProtKB:Q8TB72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:B0069630 name: PUM2_HUMAN-Phosphoserine178 def: "Protein PUM2_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q8TB72] xref: UniProtKB:Q8TB72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:B0069631 name: PUM2_HUMAN-Phosphoserine182 def: "Protein PUM2_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q8TB72] xref: UniProtKB:Q8TB72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:B0069632 name: PUM2_HUMAN-Phosphothreonine184 def: "Protein PUM2_HUMAN with the residue 184 substituted with Phosphothreonine" [UniProtKB:Q8TB72] xref: UniProtKB:Q8TB72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:B0069633 name: PUM2_HUMAN-Phosphoserine587 def: "Protein PUM2_HUMAN with the residue 587 substituted with Phosphoserine" [UniProtKB:Q8TB72] xref: UniProtKB:Q8TB72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:B0069634 name: PUR6_HUMAN-N-acetylalanine2 def: "Protein PUR6_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P22234] xref: UniProtKB:P22234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063387 ! PUR6_HUMAN [Term] id: CCO:B0069635 name: PUR6_HUMAN-Phosphoserine27 def: "Protein PUR6_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:P22234] xref: UniProtKB:P22234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001012 ! phosphoribosylaminoimidazole carboxylase activity relationship: has_function CCO:F0001013 ! phosphoribosylaminoimidazolesuccinocarboxamide synthase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003396 ! lyase activity relationship: has_function CCO:F0003398 ! carboxy-lyase activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000568 ! phosphoribosylaminoimidazole carboxylase complex relationship: transformation_of CCO:B0063387 ! PUR6_HUMAN [Term] id: CCO:B0069636 name: PURA_HUMAN-Phosphoserine6 def: "Protein PURA_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q00577] xref: UniProtKB:Q00577 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055679 ! PURA_HUMAN [Term] id: CCO:B0069637 name: PURA_HUMAN-Phosphoserine8 def: "Protein PURA_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q00577] xref: UniProtKB:Q00577 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000283 ! double-stranded telomeric DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000111 ! nuclear chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000267 ! DNA replication factor A complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055679 ! PURA_HUMAN [Term] id: CCO:B0069638 name: PURA_HUMAN-Phosphoserine182 def: "Protein PURA_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q00577] xref: UniProtKB:Q00577 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055679 ! PURA_HUMAN [Term] id: CCO:B0069639 name: PURA_HUMAN-Phosphotyrosine253 def: "Protein PURA_HUMAN with the residue 253 substituted with Phosphotyrosine" [UniProtKB:Q00577] comment: By similarity xref: UniProtKB:Q00577 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055679 ! PURA_HUMAN [Term] id: CCO:B0069640 name: PVRL2_HUMAN-Phosphoserine433 def: "Protein PVRL2_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:Q92692] xref: UniProtKB:Q92692 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002529 ! coreceptor activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0062928 ! PVRL2_HUMAN [Term] id: CCO:B0069641 name: PWP2_HUMAN-Phosphothreonine746 def: "Protein PWP2_HUMAN with the residue 746 substituted with Phosphothreonine" [UniProtKB:Q15269] xref: UniProtKB:Q15269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056050 ! PWP2_HUMAN [Term] id: CCO:B0069642 name: PWP2_HUMAN-Phosphoserine891 def: "Protein PWP2_HUMAN with the residue 891 substituted with Phosphoserine" [UniProtKB:Q15269] xref: UniProtKB:Q15269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056050 ! PWP2_HUMAN [Term] id: CCO:B0069643 name: PWP2_HUMAN-Phosphoserine898 def: "Protein PWP2_HUMAN with the residue 898 substituted with Phosphoserine" [UniProtKB:Q15269] xref: UniProtKB:Q15269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056050 ! PWP2_HUMAN [Term] id: CCO:B0069644 name: PWP2_HUMAN-Phosphoserine902 def: "Protein PWP2_HUMAN with the residue 902 substituted with Phosphoserine" [UniProtKB:Q15269] xref: UniProtKB:Q15269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000698 ! serine-type endopeptidase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056050 ! PWP2_HUMAN [Term] id: CCO:B0069645 name: PWP2_HUMAN-Phosphoserine913 def: "Protein PWP2_HUMAN with the residue 913 substituted with Phosphoserine" [UniProtKB:Q15269] xref: UniProtKB:Q15269 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056050 ! PWP2_HUMAN [Term] id: CCO:B0069646 name: PYGM_HUMAN-N-acetylserine2 def: "Protein PYGM_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P11217] comment: By similarity xref: UniProtKB:P11217 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001019 ! phosphorylase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001766 ! glycogen phosphorylase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0004337 ! pyridoxal phosphate binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063116 ! PYGM_HUMAN [Term] id: CCO:B0069647 name: PYGM_HUMAN-Phosphoserine15 def: "Protein PYGM_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:P11217] comment: by PHK; in form phosphorylase A; xref: UniProtKB:P11217 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063116 ! PYGM_HUMAN [Term] id: CCO:B0069648 name: PYGM_HUMAN-Phosphotyrosine473 def: "Protein PYGM_HUMAN with the residue 473 substituted with Phosphotyrosine" [UniProtKB:P11217] comment: By similarity xref: UniProtKB:P11217 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063116 ! PYGM_HUMAN [Term] id: CCO:B0069649 name: PYR1_HUMAN-N-acetylalanine2 def: "Protein PYR1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P27708] xref: UniProtKB:P27708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000545 ! aspartate carbamoyltransferase activity relationship: has_function CCO:F0000561 ! carbamoyl-phosphate synthase activity relationship: has_function CCO:F0000563 ! carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity relationship: has_function CCO:F0000622 ! dihydroorotase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003212 ! amino acid binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003319 ! carboxyl- or carbamoyltransferase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds relationship: has_function CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:B0069650 name: PYR1_HUMAN-Phosphoserine1423 def: "Protein PYR1_HUMAN with the residue 1423 substituted with Phosphoserine" [UniProtKB:P27708] xref: UniProtKB:P27708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:B0069651 name: PYR1_HUMAN-Phosphoserine1823 def: "Protein PYR1_HUMAN with the residue 1823 substituted with Phosphoserine" [UniProtKB:P27708] xref: UniProtKB:P27708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:B0069652 name: PYR1_HUMAN-Phosphoserine1859 def: "Protein PYR1_HUMAN with the residue 1859 substituted with Phosphoserine" [UniProtKB:P27708] xref: UniProtKB:P27708 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:B0069653 name: PYR5_HUMAN-Phosphotyrosine37 def: "Protein PYR5_HUMAN with the residue 37 substituted with Phosphotyrosine" [UniProtKB:P11172] xref: UniProtKB:P11172 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063493 ! PYR5_HUMAN [Term] id: CCO:B0069654 name: PYY_HUMAN-Phosphoserine41 def: "Protein PYY_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:P10082] comment: By similarity xref: UniProtKB:P10082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0054969 ! PYY_HUMAN [Term] id: CCO:B0069655 name: PYY_HUMAN-Tyrosine amide64 def: "Protein PYY_HUMAN with the residue 64 substituted with Tyrosine amide" [UniProtKB:P10082] xref: UniProtKB:P10082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054969 ! PYY_HUMAN [Term] id: CCO:B0069656 name: QORX_HUMAN-N-acetylmethionine1 def: "Protein QORX_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q53FA7] xref: UniProtKB:Q53FA7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056356 ! QORX_HUMAN [Term] id: CCO:B0069657 name: QSK_HUMAN-Phosphothreonine163 def: "Protein QSK_HUMAN with the residue 163 substituted with Phosphothreonine" [UniProtKB:Q9Y2K2] xref: UniProtKB:Q9Y2K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:B0069658 name: QSK_HUMAN-Phosphoserine167 def: "Protein QSK_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:Q9Y2K2] comment: By similarity xref: UniProtKB:Q9Y2K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:B0069659 name: QSK_HUMAN-Phosphoserine533 def: "Protein QSK_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:Q9Y2K2] comment: By similarity xref: UniProtKB:Q9Y2K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:B0069660 name: QSK_HUMAN-Phosphoserine534 def: "Protein QSK_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:Q9Y2K2] comment: By similarity xref: UniProtKB:Q9Y2K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:B0069661 name: QSK_HUMAN-Phosphoserine568 def: "Protein QSK_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:Q9Y2K2] xref: UniProtKB:Q9Y2K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:B0069662 name: RAB12_HUMAN-Phosphoserine21 def: "Protein RAB12_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q6IQ22] xref: UniProtKB:Q6IQ22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056826 ! RAB12_HUMAN [Term] id: CCO:B0069663 name: RAB12_HUMAN-Phosphoserine25 def: "Protein RAB12_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q6IQ22] xref: UniProtKB:Q6IQ22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056826 ! RAB12_HUMAN [Term] id: CCO:B0069664 name: RAB12_HUMAN-Phosphoserine106 def: "Protein RAB12_HUMAN with the residue 106 substituted with Phosphoserine" [UniProtKB:Q6IQ22] comment: By similarity xref: UniProtKB:Q6IQ22 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056826 ! RAB12_HUMAN [Term] id: CCO:B0069665 name: RAB13_HUMAN-Phosphoserine178 def: "Protein RAB13_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:P51153] xref: UniProtKB:P51153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0032555 ! RAB13_HUMAN [Term] id: CCO:B0069666 name: RAB14_HUMAN-N-acetylalanine2 def: "Protein RAB14_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P61106] xref: UniProtKB:P61106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055604 ! RAB14_HUMAN [Term] id: CCO:B0069667 name: RAB14_HUMAN-Phosphothreonine98 def: "Protein RAB14_HUMAN with the residue 98 substituted with Phosphothreonine" [UniProtKB:P61106] comment: By similarity xref: UniProtKB:P61106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000372 ! rough endoplasmic reticulum relationship: located_in CCO:C0000376 ! Golgi stack relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000984 ! trans-Golgi network transport vesicle relationship: located_in CCO:C0001635 ! nuclear envelope-endoplasmic reticulum network relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0055604 ! RAB14_HUMAN [Term] id: CCO:B0069668 name: RAB14_HUMAN-Phosphotyrosine99 def: "Protein RAB14_HUMAN with the residue 99 substituted with Phosphotyrosine" [UniProtKB:P61106] comment: By similarity xref: UniProtKB:P61106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055604 ! RAB14_HUMAN [Term] id: CCO:B0069669 name: RAB14_HUMAN-Cysteine methyl ester215 def: "Protein RAB14_HUMAN with the residue 215 substituted with Cysteine methyl ester" [UniProtKB:P61106] comment: By similarity xref: UniProtKB:P61106 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055604 ! RAB14_HUMAN [Term] id: CCO:B0069670 name: RAB15_HUMAN-Cysteine methyl ester212 def: "Protein RAB15_HUMAN with the residue 212 substituted with Cysteine methyl ester" [UniProtKB:P59190] comment: By similarity xref: UniProtKB:P59190 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055575 ! RAB15_HUMAN [Term] id: CCO:B0069671 name: RAB18_HUMAN-Phosphothreonine29 def: "Protein RAB18_HUMAN with the residue 29 substituted with Phosphothreonine" [UniProtKB:Q9NP72] xref: UniProtKB:Q9NP72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058836 ! RAB18_HUMAN [Term] id: CCO:B0069672 name: RAB19_HUMAN-Cysteine methyl ester217 def: "Protein RAB19_HUMAN with the residue 217 substituted with Cysteine methyl ester" [UniProtKB:A4D1S5] comment: By similarity xref: UniProtKB:A4D1S5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053752 ! RAB19_HUMAN [Term] id: CCO:B0069673 name: RAB1B_HUMAN-N-acetylmethionine1 def: "Protein RAB1B_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q9H0U4] xref: UniProtKB:Q9H0U4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0026021 ! RAB1B_HUMAN [Term] id: CCO:B0069674 name: RAB21_HUMAN-N-acetylalanine2 def: "Protein RAB21_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9UL25] xref: UniProtKB:Q9UL25 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059214 ! RAB21_HUMAN [Term] id: CCO:B0069675 name: RAB31_HUMAN-Phosphoserine35 def: "Protein RAB31_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q13636] xref: UniProtKB:Q13636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063521 ! RAB31_HUMAN [Term] id: CCO:B0069676 name: RAB32_HUMAN-N-acetylalanine2 def: "Protein RAB32_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q13637] xref: UniProtKB:Q13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0055936 ! RAB32_HUMAN [Term] id: CCO:B0069677 name: RAB32_HUMAN-Phosphoserine71 def: "Protein RAB32_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q13637] xref: UniProtKB:Q13637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055936 ! RAB32_HUMAN [Term] id: CCO:B0069678 name: RAB34_HUMAN-Phosphoserine241 def: "Protein RAB34_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:Q9BZG1] xref: UniProtKB:Q9BZG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: transformation_of CCO:B0058598 ! RAB34_HUMAN [Term] id: CCO:B0069679 name: RAB3A_HUMAN-Phosphoserine37 def: "Protein RAB3A_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:P20336] comment: By similarity xref: UniProtKB:P20336 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055116 ! RAB3A_HUMAN [Term] id: CCO:B0069680 name: RAB3A_HUMAN-Phosphoserine188 def: "Protein RAB3A_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:P20336] comment: By similarity xref: UniProtKB:P20336 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055116 ! RAB3A_HUMAN [Term] id: CCO:B0069681 name: RAB3A_HUMAN-Cysteine methyl ester220 def: "Protein RAB3A_HUMAN with the residue 220 substituted with Cysteine methyl ester" [UniProtKB:P20336] xref: UniProtKB:P20336 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055116 ! RAB3A_HUMAN [Term] id: CCO:B0069682 name: RAB3B_HUMAN-Phosphoserine188 def: "Protein RAB3B_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:P20337] comment: By similarity xref: UniProtKB:P20337 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055117 ! RAB3B_HUMAN [Term] id: CCO:B0069683 name: RAB3B_HUMAN-Cysteine methyl ester219 def: "Protein RAB3B_HUMAN with the residue 219 substituted with Cysteine methyl ester" [UniProtKB:P20337] comment: By similarity xref: UniProtKB:P20337 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000985 ! secretory granule relationship: transformation_of CCO:B0055117 ! RAB3B_HUMAN [Term] id: CCO:B0069684 name: RAB3C_HUMAN-Cysteine methyl ester227 def: "Protein RAB3C_HUMAN with the residue 227 substituted with Cysteine methyl ester" [UniProtKB:Q96E17] comment: By similarity xref: UniProtKB:Q96E17 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058200 ! RAB3C_HUMAN [Term] id: CCO:B0069685 name: RAB3D_HUMAN-Cysteine methyl ester219 def: "Protein RAB3D_HUMAN with the residue 219 substituted with Cysteine methyl ester" [UniProtKB:O95716] comment: By similarity xref: UniProtKB:O95716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054785 ! RAB3D_HUMAN [Term] id: CCO:B0069686 name: RAB42_HUMAN-Cysteine methyl ester105 def: "Protein RAB42_HUMAN with the residue 105 substituted with Cysteine methyl ester" [UniProtKB:Q8N4Z0] comment: By similarity xref: UniProtKB:Q8N4Z0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057468 ! RAB42_HUMAN [Term] id: CCO:B0069687 name: RAB43_HUMAN-Phosphoserine193 def: "Protein RAB43_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:Q86YS6] xref: UniProtKB:Q86YS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057311 ! RAB43_HUMAN [Term] id: CCO:B0069688 name: RAB43_HUMAN-Cysteine methyl ester212 def: "Protein RAB43_HUMAN with the residue 212 substituted with Cysteine methyl ester" [UniProtKB:Q86YS6] comment: By similarity xref: UniProtKB:Q86YS6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057311 ! RAB43_HUMAN [Term] id: CCO:B0069689 name: RAB4B_HUMAN-Cysteine methyl ester213 def: "Protein RAB4B_HUMAN with the residue 213 substituted with Cysteine methyl ester" [UniProtKB:P61018] comment: By similarity xref: UniProtKB:P61018 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055601 ! RAB4B_HUMAN [Term] id: CCO:B0069690 name: RAB6A_HUMAN-N-acetylserine2 def: "Protein RAB6A_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P20340] xref: UniProtKB:P20340 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055118 ! RAB6A_HUMAN [Term] id: CCO:B0069691 name: RAB6A_HUMAN-Phosphothreonine180 def: "Protein RAB6A_HUMAN with the residue 180 substituted with Phosphothreonine" [UniProtKB:P20340] comment: By similarity xref: UniProtKB:P20340 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055118 ! RAB6A_HUMAN [Term] id: CCO:B0069692 name: RAB6A_HUMAN-Cysteine methyl ester208 def: "Protein RAB6A_HUMAN with the residue 208 substituted with Cysteine methyl ester" [UniProtKB:P20340] comment: By similarity xref: UniProtKB:P20340 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055118 ! RAB6A_HUMAN [Term] id: CCO:B0069693 name: RAB6B_HUMAN-Cysteine methyl ester208 def: "Protein RAB6B_HUMAN with the residue 208 substituted with Cysteine methyl ester" [UniProtKB:Q9NRW1] comment: By similarity xref: UniProtKB:Q9NRW1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058905 ! RAB6B_HUMAN [Term] id: CCO:B0069694 name: RAB7A_HUMAN-Phosphoserine72 def: "Protein RAB7A_HUMAN with the residue 72 substituted with Phosphoserine" [UniProtKB:P51149] xref: UniProtKB:P51149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055457 ! RAB7A_HUMAN [Term] id: CCO:B0069695 name: RAB7A_HUMAN-Phosphotyrosine183 def: "Protein RAB7A_HUMAN with the residue 183 substituted with Phosphotyrosine" [UniProtKB:P51149] xref: UniProtKB:P51149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055457 ! RAB7A_HUMAN [Term] id: CCO:B0069696 name: RAB7A_HUMAN-Cysteine methyl ester207 def: "Protein RAB7A_HUMAN with the residue 207 substituted with Cysteine methyl ester" [UniProtKB:P51149] comment: By similarity xref: UniProtKB:P51149 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000347 ! lysosome relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0055457 ! RAB7A_HUMAN [Term] id: CCO:B0069697 name: RAB8A_HUMAN-Phosphothreonine192 def: "Protein RAB8A_HUMAN with the residue 192 substituted with Phosphothreonine" [UniProtKB:P61006] xref: UniProtKB:P61006 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032548 ! RAB8A_HUMAN [Term] id: CCO:B0069698 name: RAB9A_HUMAN-Phosphoserine179 def: "Protein RAB9A_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:P51151] xref: UniProtKB:P51151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055458 ! RAB9A_HUMAN [Term] id: CCO:B0069699 name: RABE1_HUMAN-Phosphoserine407 def: "Protein RABE1_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q15276] xref: UniProtKB:Q15276 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063285 ! RABE1_HUMAN [Term] id: CCO:B0069700 name: RABE1_HUMAN-Phosphothreonine408 def: "Protein RABE1_HUMAN with the residue 408 substituted with Phosphothreonine" [UniProtKB:Q15276] xref: UniProtKB:Q15276 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063285 ! RABE1_HUMAN [Term] id: CCO:B0069701 name: RABE1_HUMAN-Phosphoserine410 def: "Protein RABE1_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q15276] xref: UniProtKB:Q15276 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063285 ! RABE1_HUMAN [Term] id: CCO:B0069702 name: RAC2_HUMAN-ADP-ribosylasparagine39 def: "Protein RAC2_HUMAN with the residue 39 substituted with ADP-ribosylasparagine" [UniProtKB:P15153] comment: by botulinum toxin; By similarity xref: UniProtKB:P15153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000253 ! nuclear envelope relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0025802 ! RAC2_HUMAN [Term] id: CCO:B0069703 name: RAC2_HUMAN-Cysteine methyl ester189 def: "Protein RAC2_HUMAN with the residue 189 substituted with Cysteine methyl ester" [UniProtKB:P15153] comment: Probable xref: UniProtKB:P15153 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025802 ! RAC2_HUMAN [Term] id: CCO:B0069704 name: RAC3_HUMAN-Phosphothreonine167 def: "Protein RAC3_HUMAN with the residue 167 substituted with Phosphothreonine" [UniProtKB:P60763] xref: UniProtKB:P60763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025814 ! RAC3_HUMAN [Term] id: CCO:B0069705 name: RAC3_HUMAN-Cysteine methyl ester189 def: "Protein RAC3_HUMAN with the residue 189 substituted with Cysteine methyl ester" [UniProtKB:P60763] comment: By similarity xref: UniProtKB:P60763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0025814 ! RAC3_HUMAN [Term] id: CCO:B0069706 name: RADIL_HUMAN-Phosphoserine206 def: "Protein RADIL_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q96JH8] comment: By similarity xref: UniProtKB:Q96JH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058240 ! RADIL_HUMAN [Term] id: CCO:B0069707 name: RAI1_HUMAN-Phosphoserine683 def: "Protein RAI1_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069708 name: RAI1_HUMAN-Phosphothreonine696 def: "Protein RAI1_HUMAN with the residue 696 substituted with Phosphothreonine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069709 name: RAI1_HUMAN-Phosphoserine880 def: "Protein RAI1_HUMAN with the residue 880 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069710 name: RAI1_HUMAN-Phosphoserine892 def: "Protein RAI1_HUMAN with the residue 892 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069711 name: RAI1_HUMAN-Phosphoserine1108 def: "Protein RAI1_HUMAN with the residue 1108 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069712 name: RAI1_HUMAN-Phosphoserine1122 def: "Protein RAI1_HUMAN with the residue 1122 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069713 name: RAI1_HUMAN-Phosphoserine1352 def: "Protein RAI1_HUMAN with the residue 1352 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069714 name: RAI1_HUMAN-Phosphoserine1358 def: "Protein RAI1_HUMAN with the residue 1358 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069715 name: RAI1_HUMAN-Phosphoserine1374 def: "Protein RAI1_HUMAN with the residue 1374 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069716 name: RAI1_HUMAN-Phosphoserine1431 def: "Protein RAI1_HUMAN with the residue 1431 substituted with Phosphoserine" [UniProtKB:Q7Z5J4] xref: UniProtKB:Q7Z5J4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:B0069717 name: RAI3_HUMAN-Phosphotyrosine317 def: "Protein RAI3_HUMAN with the residue 317 substituted with Phosphotyrosine" [UniProtKB:Q8NFJ5] xref: UniProtKB:Q8NFJ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057603 ! RAI3_HUMAN [Term] id: CCO:B0069718 name: RAI3_HUMAN-Phosphotyrosine320 def: "Protein RAI3_HUMAN with the residue 320 substituted with Phosphotyrosine" [UniProtKB:Q8NFJ5] xref: UniProtKB:Q8NFJ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057603 ! RAI3_HUMAN [Term] id: CCO:B0069719 name: RAI3_HUMAN-Phosphoserine345 def: "Protein RAI3_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:Q8NFJ5] xref: UniProtKB:Q8NFJ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057603 ! RAI3_HUMAN [Term] id: CCO:B0069720 name: RAI3_HUMAN-Phosphotyrosine347 def: "Protein RAI3_HUMAN with the residue 347 substituted with Phosphotyrosine" [UniProtKB:Q8NFJ5] xref: UniProtKB:Q8NFJ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0057603 ! RAI3_HUMAN [Term] id: CCO:B0069721 name: RAI3_HUMAN-Phosphotyrosine350 def: "Protein RAI3_HUMAN with the residue 350 substituted with Phosphotyrosine" [UniProtKB:Q8NFJ5] xref: UniProtKB:Q8NFJ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057603 ! RAI3_HUMAN [Term] id: CCO:B0069722 name: RAIN_HUMAN-Phosphoserine328 def: "Protein RAIN_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q5U651] comment: By similarity xref: UniProtKB:Q5U651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056639 ! RAIN_HUMAN [Term] id: CCO:B0069723 name: RAIN_HUMAN-Phosphoserine331 def: "Protein RAIN_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q5U651] comment: By similarity xref: UniProtKB:Q5U651 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056639 ! RAIN_HUMAN [Term] id: CCO:B0069724 name: RALA_HUMAN-Cysteine methyl ester203 def: "Protein RALA_HUMAN with the residue 203 substituted with Cysteine methyl ester" [UniProtKB:P11233] comment: Probable xref: UniProtKB:P11233 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054988 ! RALA_HUMAN [Term] id: CCO:B0069725 name: RALB_HUMAN-Cysteine methyl ester203 def: "Protein RALB_HUMAN with the residue 203 substituted with Cysteine methyl ester" [UniProtKB:P11234] comment: By similarity xref: UniProtKB:P11234 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054989 ! RALB_HUMAN [Term] id: CCO:B0069726 name: RANB3_HUMAN-Phosphothreonine124 def: "Protein RANB3_HUMAN with the residue 124 substituted with Phosphothreonine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0069727 name: RANB3_HUMAN-Phosphoserine353 def: "Protein RANB3_HUMAN with the residue 353 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0069728 name: RANB3_HUMAN-Phosphoserine355 def: "Protein RANB3_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001985 ! Ran GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0069729 name: RANB3_HUMAN-Phosphoserine357 def: "Protein RANB3_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0069730 name: RANB3_HUMAN-Phosphoserine539 def: "Protein RANB3_HUMAN with the residue 539 substituted with Phosphoserine" [UniProtKB:Q9H6Z4] xref: UniProtKB:Q9H6Z4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:B0069731 name: RANB9_HUMAN-Phosphoserine603 def: "Protein RANB9_HUMAN with the residue 603 substituted with Phosphoserine" [UniProtKB:Q96S59] xref: UniProtKB:Q96S59 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063004 ! RANB9_HUMAN [Term] id: CCO:B0069732 name: RANG_HUMAN-Phosphothreonine7 def: "Protein RANG_HUMAN with the residue 7 substituted with Phosphothreonine" [UniProtKB:P43487] xref: UniProtKB:P43487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001397 ! GDP-dissociation inhibitor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001985 ! Ran GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:B0069733 name: RAN_HUMAN-Phosphotyrosine155 def: "Protein RAN_HUMAN with the residue 155 substituted with Phosphotyrosine" [UniProtKB:P62826] xref: UniProtKB:P62826 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001693 ! RAN_HUMAN [Term] id: CCO:B0069734 name: RAPH1_HUMAN-Phosphoserine54 def: "Protein RAPH1_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069735 name: RAPH1_HUMAN-Phosphoserine610 def: "Protein RAPH1_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069736 name: RAPH1_HUMAN-Phosphoserine827 def: "Protein RAPH1_HUMAN with the residue 827 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069737 name: RAPH1_HUMAN-Phosphothreonine830 def: "Protein RAPH1_HUMAN with the residue 830 substituted with Phosphothreonine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069738 name: RAPH1_HUMAN-Phosphoserine853 def: "Protein RAPH1_HUMAN with the residue 853 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069739 name: RAPH1_HUMAN-Phosphoserine860 def: "Protein RAPH1_HUMAN with the residue 860 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069740 name: RAPH1_HUMAN-Phosphoserine894 def: "Protein RAPH1_HUMAN with the residue 894 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069741 name: RAPH1_HUMAN-Phosphoserine965 def: "Protein RAPH1_HUMAN with the residue 965 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069742 name: RAPH1_HUMAN-Phosphothreonine974 def: "Protein RAPH1_HUMAN with the residue 974 substituted with Phosphothreonine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069743 name: RAPH1_HUMAN-Phosphoserine1154 def: "Protein RAPH1_HUMAN with the residue 1154 substituted with Phosphoserine" [UniProtKB:Q70E73] xref: UniProtKB:Q70E73 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057092 ! RAPH1_HUMAN [Term] id: CCO:B0069744 name: RASA3_HUMAN-Phosphotyrosine66 def: "Protein RASA3_HUMAN with the residue 66 substituted with Phosphotyrosine" [UniProtKB:Q14644] comment: By similarity xref: UniProtKB:Q14644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056008 ! RASA3_HUMAN [Term] id: CCO:B0069745 name: RASA3_HUMAN-Phosphoserine77 def: "Protein RASA3_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q14644] xref: UniProtKB:Q14644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056008 ! RASA3_HUMAN [Term] id: CCO:B0069746 name: RASA3_HUMAN-Phosphothreonine110 def: "Protein RASA3_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:Q14644] xref: UniProtKB:Q14644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056008 ! RASA3_HUMAN [Term] id: CCO:B0069747 name: RASA3_HUMAN-Phosphotyrosine765 def: "Protein RASA3_HUMAN with the residue 765 substituted with Phosphotyrosine" [UniProtKB:Q14644] xref: UniProtKB:Q14644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056008 ! RASA3_HUMAN [Term] id: CCO:B0069748 name: RASA3_HUMAN-Phosphoserine809 def: "Protein RASA3_HUMAN with the residue 809 substituted with Phosphoserine" [UniProtKB:Q14644] xref: UniProtKB:Q14644 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056008 ! RASA3_HUMAN [Term] id: CCO:B0069749 name: RASD1_HUMAN-S-nitrosocysteine11 def: "Protein RASD1_HUMAN with the residue 11 substituted with S-nitrosocysteine" [UniProtKB:Q9Y272] xref: UniProtKB:Q9Y272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0059295 ! RASD1_HUMAN [Term] id: CCO:B0069750 name: RASD1_HUMAN-Cysteine methyl ester278 def: "Protein RASD1_HUMAN with the residue 278 substituted with Cysteine methyl ester" [UniProtKB:Q9Y272] comment: By similarity xref: UniProtKB:Q9Y272 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059295 ! RASD1_HUMAN [Term] id: CCO:B0069751 name: RASEF_HUMAN-Phosphoserine523 def: "Protein RASEF_HUMAN with the residue 523 substituted with Phosphoserine" [UniProtKB:Q8IZ41] xref: UniProtKB:Q8IZ41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057398 ! RASEF_HUMAN [Term] id: CCO:B0069752 name: RASEF_HUMAN-Phosphothreonine526 def: "Protein RASEF_HUMAN with the residue 526 substituted with Phosphothreonine" [UniProtKB:Q8IZ41] xref: UniProtKB:Q8IZ41 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057398 ! RASEF_HUMAN [Term] id: CCO:B0069753 name: RASE_HUMAN-Cysteine methyl ester230 def: "Protein RASE_HUMAN with the residue 230 substituted with Cysteine methyl ester" [UniProtKB:Q7Z444] comment: By similarity xref: UniProtKB:Q7Z444 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057161 ! RASE_HUMAN [Term] id: CCO:B0069754 name: RASF8_HUMAN-Phosphoserine105 def: "Protein RASF8_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q8NHQ8] xref: UniProtKB:Q8NHQ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043423 ! RASF8_HUMAN [Term] id: CCO:B0069755 name: RASM_HUMAN-Cysteine methyl ester205 def: "Protein RASM_HUMAN with the residue 205 substituted with Cysteine methyl ester" [UniProtKB:O14807] comment: By similarity xref: UniProtKB:O14807 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054379 ! RASM_HUMAN [Term] id: CCO:B0069756 name: RB27B_HUMAN-N-acetylthreonine2 def: "Protein RB27B_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:O00194] xref: UniProtKB:O00194 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054297 ! RB27B_HUMAN [Term] id: CCO:B0069757 name: RB27B_HUMAN-Cysteine methyl ester218 def: "Protein RB27B_HUMAN with the residue 218 substituted with Cysteine methyl ester" [UniProtKB:O00194] comment: By similarity xref: UniProtKB:O00194 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054297 ! RB27B_HUMAN [Term] id: CCO:B0069758 name: RB33A_HUMAN-Cysteine methyl ester237 def: "Protein RB33A_HUMAN with the residue 237 substituted with Cysteine methyl ester" [UniProtKB:Q14088] comment: By similarity xref: UniProtKB:Q14088 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055956 ! RB33A_HUMAN [Term] id: CCO:B0069759 name: RB33B_HUMAN-Cysteine methyl ester229 def: "Protein RB33B_HUMAN with the residue 229 substituted with Cysteine methyl ester" [UniProtKB:Q9H082] comment: By similarity xref: UniProtKB:Q9H082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058649 ! RB33B_HUMAN [Term] id: CCO:B0069760 name: RB39A_HUMAN-Cysteine methyl ester217 def: "Protein RB39A_HUMAN with the residue 217 substituted with Cysteine methyl ester" [UniProtKB:Q14964] comment: By similarity xref: UniProtKB:Q14964 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056028 ! RB39A_HUMAN [Term] id: CCO:B0069761 name: RB39B_HUMAN-Cysteine methyl ester213 def: "Protein RB39B_HUMAN with the residue 213 substituted with Cysteine methyl ester" [UniProtKB:Q96DA2] comment: By similarity xref: UniProtKB:Q96DA2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058191 ! RB39B_HUMAN [Term] id: CCO:B0069762 name: RB43L_HUMAN-Cysteine methyl ester181 def: "Protein RB43L_HUMAN with the residue 181 substituted with Cysteine methyl ester" [UniProtKB:A6NDJ8] comment: By similarity xref: UniProtKB:A6NDJ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053791 ! RB43L_HUMAN [Term] id: CCO:B0069763 name: RB6I2_HUMAN-Phosphoserine17 def: "Protein RB6I2_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q8IUD2] xref: UniProtKB:Q8IUD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005865 ! leucine zipper domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000547 ! IkappaB kinase complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: transformation_of CCO:B0057322 ! RB6I2_HUMAN [Term] id: CCO:B0069764 name: RB6I2_HUMAN-Phosphoserine21 def: "Protein RB6I2_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q8IUD2] xref: UniProtKB:Q8IUD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057322 ! RB6I2_HUMAN [Term] id: CCO:B0069765 name: RB6I2_HUMAN-Phosphoserine191 def: "Protein RB6I2_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q8IUD2] xref: UniProtKB:Q8IUD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057322 ! RB6I2_HUMAN [Term] id: CCO:B0069766 name: RB6I2_HUMAN-Phosphoserine252 def: "Protein RB6I2_HUMAN with the residue 252 substituted with Phosphoserine" [UniProtKB:Q8IUD2] comment: By similarity xref: UniProtKB:Q8IUD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057322 ! RB6I2_HUMAN [Term] id: CCO:B0069767 name: RB6I2_HUMAN-Phosphothreonine1046 def: "Protein RB6I2_HUMAN with the residue 1046 substituted with Phosphothreonine" [UniProtKB:Q8IUD2] xref: UniProtKB:Q8IUD2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057322 ! RB6I2_HUMAN [Term] id: CCO:B0069768 name: RBBP7_HUMAN-Phosphoserine354 def: "Protein RBBP7_HUMAN with the residue 354 substituted with Phosphoserine" [UniProtKB:Q16576] xref: UniProtKB:Q16576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005809 ! RBBP7_HUMAN [Term] id: CCO:B0069769 name: RBCC1_HUMAN-Phosphoserine624 def: "Protein RBCC1_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:Q8TDY2] xref: UniProtKB:Q8TDY2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001995 ! RBCC1_HUMAN [Term] id: CCO:B0069770 name: RBCC1_HUMAN-Phosphoserine647 def: "Protein RBCC1_HUMAN with the residue 647 substituted with Phosphoserine" [UniProtKB:Q8TDY2] xref: UniProtKB:Q8TDY2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001995 ! RBCC1_HUMAN [Term] id: CCO:B0069771 name: RBCC1_HUMAN-Phosphoserine653 def: "Protein RBCC1_HUMAN with the residue 653 substituted with Phosphoserine" [UniProtKB:Q8TDY2] xref: UniProtKB:Q8TDY2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001995 ! RBCC1_HUMAN [Term] id: CCO:B0069772 name: RBG1L_HUMAN-Phosphoserine118 def: "Protein RBG1L_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q5R372] comment: By similarity xref: UniProtKB:Q5R372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0033512 ! RBG1L_HUMAN [Term] id: CCO:B0069773 name: RBG1L_HUMAN-Phosphothreonine471 def: "Protein RBG1L_HUMAN with the residue 471 substituted with Phosphothreonine" [UniProtKB:Q5R372] xref: UniProtKB:Q5R372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033512 ! RBG1L_HUMAN [Term] id: CCO:B0069774 name: RBG1L_HUMAN-Phosphoserine480 def: "Protein RBG1L_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:Q5R372] xref: UniProtKB:Q5R372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033512 ! RBG1L_HUMAN [Term] id: CCO:B0069775 name: RBG1L_HUMAN-Phosphoserine490 def: "Protein RBG1L_HUMAN with the residue 490 substituted with Phosphoserine" [UniProtKB:Q5R372] xref: UniProtKB:Q5R372 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033512 ! RBG1L_HUMAN [Term] id: CCO:B0069776 name: RBGP1_HUMAN-Phosphothreonine996 def: "Protein RBGP1_HUMAN with the residue 996 substituted with Phosphothreonine" [UniProtKB:Q9Y3P9] xref: UniProtKB:Q9Y3P9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002254 ! RBGP1_HUMAN [Term] id: CCO:B0069777 name: RBM14_HUMAN-Phosphoserine161 def: "Protein RBM14_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069778 name: RBM14_HUMAN-Phosphothreonine206 def: "Protein RBM14_HUMAN with the residue 206 substituted with Phosphothreonine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069779 name: RBM14_HUMAN-Phosphoserine215 def: "Protein RBM14_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069780 name: RBM14_HUMAN-Phosphoserine220 def: "Protein RBM14_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069781 name: RBM14_HUMAN-Phosphoserine256 def: "Protein RBM14_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069782 name: RBM14_HUMAN-Phosphoserine520 def: "Protein RBM14_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:Q96PK6] comment: By similarity xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069783 name: RBM14_HUMAN-Phosphoserine562 def: "Protein RBM14_HUMAN with the residue 562 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069784 name: RBM14_HUMAN-Phosphothreonine572 def: "Protein RBM14_HUMAN with the residue 572 substituted with Phosphothreonine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0004516 ! protein binding, bridging relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069785 name: RBM14_HUMAN-Phosphoserine582 def: "Protein RBM14_HUMAN with the residue 582 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069786 name: RBM14_HUMAN-Phosphoserine618 def: "Protein RBM14_HUMAN with the residue 618 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069787 name: RBM14_HUMAN-Phosphothreonine629 def: "Protein RBM14_HUMAN with the residue 629 substituted with Phosphothreonine" [UniProtKB:Q96PK6] comment: By similarity xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069788 name: RBM14_HUMAN-Phosphoserine632 def: "Protein RBM14_HUMAN with the residue 632 substituted with Phosphoserine" [UniProtKB:Q96PK6] comment: By similarity xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069789 name: RBM14_HUMAN-Phosphoserine649 def: "Protein RBM14_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:Q96PK6] xref: UniProtKB:Q96PK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:B0069790 name: RBM15_HUMAN-Phosphoserine51 def: "Protein RBM15_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069791 name: RBM15_HUMAN-Phosphoserine83 def: "Protein RBM15_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069792 name: RBM15_HUMAN-Phosphoserine125 def: "Protein RBM15_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069793 name: RBM15_HUMAN-Phosphoserine128 def: "Protein RBM15_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069794 name: RBM15_HUMAN-Phosphoserine179 def: "Protein RBM15_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069795 name: RBM15_HUMAN-Phosphoserine257 def: "Protein RBM15_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069796 name: RBM15_HUMAN-Phosphoserine259 def: "Protein RBM15_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069797 name: RBM15_HUMAN-Phosphoserine292 def: "Protein RBM15_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069798 name: RBM15_HUMAN-Phosphoserine294 def: "Protein RBM15_HUMAN with the residue 294 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069799 name: RBM15_HUMAN-Phosphoserine365 def: "Protein RBM15_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069800 name: RBM15_HUMAN-Phosphothreonine568 def: "Protein RBM15_HUMAN with the residue 568 substituted with Phosphothreonine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069801 name: RBM15_HUMAN-Phosphoserine622 def: "Protein RBM15_HUMAN with the residue 622 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069802 name: RBM15_HUMAN-Phosphoserine656 def: "Protein RBM15_HUMAN with the residue 656 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069803 name: RBM15_HUMAN-Phosphoserine659 def: "Protein RBM15_HUMAN with the residue 659 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069804 name: RBM15_HUMAN-Phosphoserine670 def: "Protein RBM15_HUMAN with the residue 670 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069805 name: RBM15_HUMAN-Phosphoserine674 def: "Protein RBM15_HUMAN with the residue 674 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069806 name: RBM15_HUMAN-Phosphoserine700 def: "Protein RBM15_HUMAN with the residue 700 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069807 name: RBM15_HUMAN-Phosphoserine708 def: "Protein RBM15_HUMAN with the residue 708 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069808 name: RBM15_HUMAN-Phosphoserine724 def: "Protein RBM15_HUMAN with the residue 724 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069809 name: RBM15_HUMAN-Phosphoserine741 def: "Protein RBM15_HUMAN with the residue 741 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069810 name: RBM15_HUMAN-Phosphoserine935 def: "Protein RBM15_HUMAN with the residue 935 substituted with Phosphoserine" [UniProtKB:Q96T37] xref: UniProtKB:Q96T37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058400 ! RBM15_HUMAN [Term] id: CCO:B0069811 name: RBM39_HUMAN-Phosphotyrosine95 def: "Protein RBM39_HUMAN with the residue 95 substituted with Phosphotyrosine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069812 name: RBM39_HUMAN-Phosphoserine97 def: "Protein RBM39_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069813 name: RBM39_HUMAN-Phosphoserine100 def: "Protein RBM39_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069814 name: RBM39_HUMAN-Phosphoserine117 def: "Protein RBM39_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069815 name: RBM39_HUMAN-Phosphoserine127 def: "Protein RBM39_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069816 name: RBM39_HUMAN-Phosphoserine129 def: "Protein RBM39_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069817 name: RBM39_HUMAN-Phosphoserine136 def: "Protein RBM39_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069818 name: RBM39_HUMAN-Phosphoserine334 def: "Protein RBM39_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069819 name: RBM39_HUMAN-Phosphoserine337 def: "Protein RBM39_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069820 name: RBM39_HUMAN-Phosphoserine341 def: "Protein RBM39_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q14498] xref: UniProtKB:Q14498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055987 ! RBM39_HUMAN [Term] id: CCO:B0069821 name: RBM41_HUMAN-Phosphoserine232 def: "Protein RBM41_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q96IZ5] xref: UniProtKB:Q96IZ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062777 ! RBM41_HUMAN [Term] id: CCO:B0069822 name: RBM7_HUMAN-Phosphoserine134 def: "Protein RBM7_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q9Y580] xref: UniProtKB:Q9Y580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002255 ! RBM7_HUMAN [Term] id: CCO:B0069823 name: RBM8A_HUMAN-Phosphoserine56 def: "Protein RBM8A_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:Q9Y5S9] xref: UniProtKB:Q9Y5S9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005223 ! RBM8A_HUMAN [Term] id: CCO:B0069824 name: RBMS1_HUMAN-Phosphoserine112 def: "Protein RBMS1_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:P29558] xref: UniProtKB:P29558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015073 ! RBMS1_HUMAN [Term] id: CCO:B0069825 name: RBMS1_HUMAN-Phosphothreonine208 def: "Protein RBMS1_HUMAN with the residue 208 substituted with Phosphothreonine" [UniProtKB:P29558] xref: UniProtKB:P29558 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015073 ! RBMS1_HUMAN [Term] id: CCO:B0069826 name: RBP1_HUMAN-Phosphothreonine27 def: "Protein RBP1_HUMAN with the residue 27 substituted with Phosphothreonine" [UniProtKB:Q15311] xref: UniProtKB:Q15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:B0069827 name: RBP1_HUMAN-Phosphoserine29 def: "Protein RBP1_HUMAN with the residue 29 substituted with Phosphoserine" [UniProtKB:Q15311] xref: UniProtKB:Q15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:B0069828 name: RBP1_HUMAN-Phosphoserine34 def: "Protein RBP1_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:Q15311] xref: UniProtKB:Q15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:B0069829 name: RBP1_HUMAN-Phosphoserine62 def: "Protein RBP1_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:Q15311] xref: UniProtKB:Q15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:B0069830 name: RBP1_HUMAN-Phosphoserine92 def: "Protein RBP1_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q15311] xref: UniProtKB:Q15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:B0069831 name: RBP1_HUMAN-Phosphoserine93 def: "Protein RBP1_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q15311] xref: UniProtKB:Q15311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0003600 ! Ral GTPase binding relationship: has_function CCO:F0004517 ! Rac GTPase activator activity relationship: has_function CCO:F0005860 ! ATPase activity, coupled to movement of substances relationship: has_function CCO:F0007332 ! Rac GTPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:B0069832 name: RBPMS_HUMAN-Phosphothreonine113 def: "Protein RBPMS_HUMAN with the residue 113 substituted with Phosphothreonine" [UniProtKB:Q93062] xref: UniProtKB:Q93062 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005178 ! RBPMS_HUMAN [Term] id: CCO:B0069833 name: RBPMS_HUMAN-Phosphothreonine118 def: "Protein RBPMS_HUMAN with the residue 118 substituted with Phosphothreonine" [UniProtKB:Q93062] xref: UniProtKB:Q93062 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005178 ! RBPMS_HUMAN [Term] id: CCO:B0069834 name: RBX2_HUMAN-Phosphothreonine10 def: "Protein RBX2_HUMAN with the residue 10 substituted with Phosphothreonine" [UniProtKB:Q9UBF6] comment: by CK2; xref: UniProtKB:Q9UBF6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059071 ! RBX2_HUMAN [Term] id: CCO:B0069835 name: RCAN3_HUMAN-Phosphotyrosine120 def: "Protein RCAN3_HUMAN with the residue 120 substituted with Phosphotyrosine" [UniProtKB:Q9UKA8] comment: By similarity xref: UniProtKB:Q9UKA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059190 ! RCAN3_HUMAN [Term] id: CCO:B0069836 name: RCAN3_HUMAN-Phosphoserine148 def: "Protein RCAN3_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q9UKA8] xref: UniProtKB:Q9UKA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059190 ! RCAN3_HUMAN [Term] id: CCO:B0069837 name: RCAN3_HUMAN-Phosphoserine152 def: "Protein RCAN3_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q9UKA8] xref: UniProtKB:Q9UKA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059190 ! RCAN3_HUMAN [Term] id: CCO:B0069838 name: RCAS1_HUMAN-Phosphoserine36 def: "Protein RCAS1_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:O00559] xref: UniProtKB:O00559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054331 ! RCAS1_HUMAN [Term] id: CCO:B0069839 name: RCAS1_HUMAN-Phosphothreonine41 def: "Protein RCAS1_HUMAN with the residue 41 substituted with Phosphothreonine" [UniProtKB:O00559] xref: UniProtKB:O00559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0003186 ! apoptotic protease activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054331 ! RCAS1_HUMAN [Term] id: CCO:B0069840 name: RCAS1_HUMAN-Phosphotyrosine48 def: "Protein RCAS1_HUMAN with the residue 48 substituted with Phosphotyrosine" [UniProtKB:O00559] xref: UniProtKB:O00559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054331 ! RCAS1_HUMAN [Term] id: CCO:B0069841 name: RCAS1_HUMAN-Phosphotyrosine94 def: "Protein RCAS1_HUMAN with the residue 94 substituted with Phosphotyrosine" [UniProtKB:O00559] xref: UniProtKB:O00559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054331 ! RCAS1_HUMAN [Term] id: CCO:B0069842 name: RCL_HUMAN-Phosphoserine169 def: "Protein RCL_HUMAN with the residue 169 substituted with Phosphoserine" [UniProtKB:O43598] xref: UniProtKB:O43598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054497 ! RCL_HUMAN [Term] id: CCO:B0069843 name: RCOR1_HUMAN-Phosphoserine124 def: "Protein RCOR1_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q9UKL0] xref: UniProtKB:Q9UKL0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059194 ! RCOR1_HUMAN [Term] id: CCO:B0069844 name: RCOR1_HUMAN-Phosphoserine257 def: "Protein RCOR1_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:Q9UKL0] xref: UniProtKB:Q9UKL0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059194 ! RCOR1_HUMAN [Term] id: CCO:B0069845 name: RCOR1_HUMAN-Phosphoserine457 def: "Protein RCOR1_HUMAN with the residue 457 substituted with Phosphoserine" [UniProtKB:Q9UKL0] xref: UniProtKB:Q9UKL0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059194 ! RCOR1_HUMAN [Term] id: CCO:B0069846 name: RCOR3_HUMAN-Phosphoserine156 def: "Protein RCOR3_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q9P2K3] xref: UniProtKB:Q9P2K3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059058 ! RCOR3_HUMAN [Term] id: CCO:B0069847 name: RD23A_HUMAN-Phosphoserine123 def: "Protein RD23A_HUMAN with the residue 123 substituted with Phosphoserine" [UniProtKB:P54725] xref: UniProtKB:P54725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:B0069848 name: RD23A_HUMAN-Phosphoserine128 def: "Protein RD23A_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:P54725] xref: UniProtKB:P54725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000279 ! damaged DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:B0069849 name: RD23A_HUMAN-Phosphoserine133 def: "Protein RD23A_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:P54725] xref: UniProtKB:P54725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:B0069850 name: RD23A_HUMAN-Phosphoserine205 def: "Protein RD23A_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:P54725] xref: UniProtKB:P54725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:B0069851 name: RD23A_HUMAN-Phosphoserine295 def: "Protein RD23A_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:P54725] xref: UniProtKB:P54725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:B0069852 name: RD23A_HUMAN-Phosphoserine357 def: "Protein RD23A_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:P54725] xref: UniProtKB:P54725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:B0069853 name: RED_HUMAN-Phosphoserine460 def: "Protein RED_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q13123] xref: UniProtKB:Q13123 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006239 ! RED_HUMAN [Term] id: CCO:B0069854 name: REG1A_HUMAN-Pyrrolidone carboxylic acid23 def: "Protein REG1A_HUMAN with the residue 23 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P05451] xref: UniProtKB:P05451 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054900 ! REG1A_HUMAN [Term] id: CCO:B0069855 name: REG1B_HUMAN-Pyrrolidone carboxylic acid23 def: "Protein REG1B_HUMAN with the residue 23 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P48304] comment: By similarity xref: UniProtKB:P48304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001659 ! sugar binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055401 ! REG1B_HUMAN [Term] id: CCO:B0069856 name: RELB_HUMAN-Phosphoserine37 def: "Protein RELB_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q01201] xref: UniProtKB:Q01201 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:B0069857 name: REL_HUMAN-Phosphoserine267 def: "Protein REL_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q04864] comment: by PKA; Potential xref: UniProtKB:Q04864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055737 ! REL_HUMAN [Term] id: CCO:B0069858 name: REL_HUMAN-Phosphoserine503 def: "Protein REL_HUMAN with the residue 503 substituted with Phosphoserine" [UniProtKB:Q04864] xref: UniProtKB:Q04864 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055737 ! REL_HUMAN [Term] id: CCO:B0069859 name: REN3B_HUMAN-Phosphothreonine169 def: "Protein REN3B_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:Q9BZI7] xref: UniProtKB:Q9BZI7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005434 ! REN3B_HUMAN [Term] id: CCO:B0069860 name: REPS1_HUMAN-Phosphoserine66 def: "Protein REPS1_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069861 name: REPS1_HUMAN-Phosphoserine110 def: "Protein REPS1_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069862 name: REPS1_HUMAN-Phosphoserine114 def: "Protein REPS1_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069863 name: REPS1_HUMAN-Phosphoserine118 def: "Protein REPS1_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069864 name: REPS1_HUMAN-Phosphothreonine121 def: "Protein REPS1_HUMAN with the residue 121 substituted with Phosphothreonine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069865 name: REPS1_HUMAN-Phosphoserine122 def: "Protein REPS1_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069866 name: REPS1_HUMAN-Phosphoserine220 def: "Protein REPS1_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q96D71] comment: By similarity xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069867 name: REPS1_HUMAN-Phosphotyrosine236 def: "Protein REPS1_HUMAN with the residue 236 substituted with Phosphotyrosine" [UniProtKB:Q96D71] comment: Potential xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069868 name: REPS1_HUMAN-Phosphoserine255 def: "Protein REPS1_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069869 name: REPS1_HUMAN-Phosphoserine437 def: "Protein REPS1_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069870 name: REPS1_HUMAN-Phosphoserine510 def: "Protein REPS1_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069871 name: REPS1_HUMAN-Phosphoserine657 def: "Protein REPS1_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069872 name: REPS1_HUMAN-Phosphoserine699 def: "Protein REPS1_HUMAN with the residue 699 substituted with Phosphoserine" [UniProtKB:Q96D71] xref: UniProtKB:Q96D71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063199 ! REPS1_HUMAN [Term] id: CCO:B0069873 name: REPS2_HUMAN-Phosphoserine260 def: "Protein REPS2_HUMAN with the residue 260 substituted with Phosphoserine" [UniProtKB:Q8NFH8] comment: By similarity xref: UniProtKB:Q8NFH8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057602 ! REPS2_HUMAN [Term] id: CCO:B0069874 name: REQU_HUMAN-Phosphoserine94 def: "Protein REQU_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:Q92785] xref: UniProtKB:Q92785 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058094 ! REQU_HUMAN [Term] id: CCO:B0069875 name: REQU_HUMAN-Phosphoserine97 def: "Protein REQU_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q92785] xref: UniProtKB:Q92785 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058094 ! REQU_HUMAN [Term] id: CCO:B0069876 name: REQU_HUMAN-Phosphoserine142 def: "Protein REQU_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q92785] xref: UniProtKB:Q92785 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058094 ! REQU_HUMAN [Term] id: CCO:B0069877 name: REQU_HUMAN-Phosphothreonine176 def: "Protein REQU_HUMAN with the residue 176 substituted with Phosphothreonine" [UniProtKB:Q92785] xref: UniProtKB:Q92785 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058094 ! REQU_HUMAN [Term] id: CCO:B0069878 name: REQU_HUMAN-Phosphoserine200 def: "Protein REQU_HUMAN with the residue 200 substituted with Phosphoserine" [UniProtKB:Q92785] xref: UniProtKB:Q92785 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058094 ! REQU_HUMAN [Term] id: CCO:B0069879 name: RER1_HUMAN-Phosphoserine95 def: "Protein RER1_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:O15258] comment: By similarity xref: UniProtKB:O15258 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063432 ! RER1_HUMAN [Term] id: CCO:B0069880 name: RERE_HUMAN-Phosphoserine53 def: "Protein RERE_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0069881 name: RERE_HUMAN-Phosphoserine56 def: "Protein RERE_HUMAN with the residue 56 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001807 ! poly-glutamine tract binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0069882 name: RERE_HUMAN-Phosphoserine642 def: "Protein RERE_HUMAN with the residue 642 substituted with Phosphoserine" [UniProtKB:Q9P2R6] xref: UniProtKB:Q9P2R6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:B0069883 name: RERG_HUMAN-Phosphothreonine177 def: "Protein RERG_HUMAN with the residue 177 substituted with Phosphothreonine" [UniProtKB:Q96A58] xref: UniProtKB:Q96A58 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058147 ! RERG_HUMAN [Term] id: CCO:B0069884 name: REST_HUMAN-Phosphoserine864 def: "Protein REST_HUMAN with the residue 864 substituted with Phosphoserine" [UniProtKB:Q13127] xref: UniProtKB:Q13127 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055876 ! REST_HUMAN [Term] id: CCO:B0069885 name: RET_HUMAN-Phosphotyrosine806 def: "Protein RET_HUMAN with the residue 806 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069886 name: RET_HUMAN-Phosphotyrosine809 def: "Protein RET_HUMAN with the residue 809 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069887 name: RET_HUMAN-Phosphotyrosine900 def: "Protein RET_HUMAN with the residue 900 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069888 name: RET_HUMAN-Phosphotyrosine905 def: "Protein RET_HUMAN with the residue 905 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069889 name: RET_HUMAN-Phosphotyrosine981 def: "Protein RET_HUMAN with the residue 981 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069890 name: RET_HUMAN-Phosphotyrosine1015 def: "Protein RET_HUMAN with the residue 1015 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069891 name: RET_HUMAN-Phosphotyrosine1062 def: "Protein RET_HUMAN with the residue 1062 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069892 name: RET_HUMAN-Phosphotyrosine1090 def: "Protein RET_HUMAN with the residue 1090 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069893 name: RET_HUMAN-Phosphotyrosine1096 def: "Protein RET_HUMAN with the residue 1096 substituted with Phosphotyrosine" [UniProtKB:P07949] comment: by autocatalysis; xref: UniProtKB:P07949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017344 ! RET_HUMAN [Term] id: CCO:B0069894 name: REXO4_HUMAN-Phosphoserine15 def: "Protein REXO4_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q9GZR2] xref: UniProtKB:Q9GZR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058634 ! REXO4_HUMAN [Term] id: CCO:B0069895 name: RFC1_HUMAN-Phosphoserine164 def: "Protein RFC1_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0069896 name: RFC1_HUMAN-Phosphothreonine171 def: "Protein RFC1_HUMAN with the residue 171 substituted with Phosphothreonine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0069897 name: RFC1_HUMAN-Phosphoserine281 def: "Protein RFC1_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0069898 name: RFC1_HUMAN-Phosphoserine283 def: "Protein RFC1_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0069899 name: RFC1_HUMAN-Phosphoserine312 def: "Protein RFC1_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:P35251] xref: UniProtKB:P35251 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:B0069900 name: RFRP_HUMAN-Phenylalanine amide92 def: "Protein RFRP_HUMAN with the residue 92 substituted with Phenylalanine amide" [UniProtKB:Q9HCQ7] comment: By similarity xref: UniProtKB:Q9HCQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058817 ! RFRP_HUMAN [Term] id: CCO:B0069901 name: RFRP_HUMAN-Phenylalanine amide131 def: "Protein RFRP_HUMAN with the residue 131 substituted with Phenylalanine amide" [UniProtKB:Q9HCQ7] comment: By similarity xref: UniProtKB:Q9HCQ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058817 ! RFRP_HUMAN [Term] id: CCO:B0069902 name: RFX7_HUMAN-Phosphoserine1081 def: "Protein RFX7_HUMAN with the residue 1081 substituted with Phosphoserine" [UniProtKB:Q2KHR2] xref: UniProtKB:Q2KHR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056202 ! RFX7_HUMAN [Term] id: CCO:B0069903 name: RGAP1_HUMAN-Phosphoserine257 def: "Protein RGAP1_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0069904 name: RGAP1_HUMAN-Phosphoserine573 def: "Protein RGAP1_HUMAN with the residue 573 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0069905 name: RGAP1_HUMAN-Phosphoserine591 def: "Protein RGAP1_HUMAN with the residue 591 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0069906 name: RGAP1_HUMAN-Phosphoserine600 def: "Protein RGAP1_HUMAN with the residue 600 substituted with Phosphoserine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005781 ! alpha-tubulin binding relationship: has_function CCO:F0005782 ! gamma-tubulin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000177 ! acrosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000388 ! spindle relationship: located_in CCO:C0000434 ! microtubule relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0069907 name: RGAP1_HUMAN-Phosphothreonine601 def: "Protein RGAP1_HUMAN with the residue 601 substituted with Phosphothreonine" [UniProtKB:Q9H0H5] xref: UniProtKB:Q9H0H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:B0069908 name: RGF1B_HUMAN-Phosphotyrosine77 def: "Protein RGF1B_HUMAN with the residue 77 substituted with Phosphotyrosine" [UniProtKB:Q0VAM2] xref: UniProtKB:Q0VAM2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0055822 ! RGF1B_HUMAN [Term] id: CCO:B0069909 name: RGL1_HUMAN-Phosphothreonine670 def: "Protein RGL1_HUMAN with the residue 670 substituted with Phosphothreonine" [UniProtKB:Q9NZL6] xref: UniProtKB:Q9NZL6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005550 ! RGL1_HUMAN [Term] id: CCO:B0069910 name: RGL2_HUMAN-Phosphoserine13 def: "Protein RGL2_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:O15211] xref: UniProtKB:O15211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0054416 ! RGL2_HUMAN [Term] id: CCO:B0069911 name: RGL2_HUMAN-Phosphoserine617 def: "Protein RGL2_HUMAN with the residue 617 substituted with Phosphoserine" [UniProtKB:O15211] comment: By similarity xref: UniProtKB:O15211 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054416 ! RGL2_HUMAN [Term] id: CCO:B0069912 name: RGL3_HUMAN-Phosphoserine52 def: "Protein RGL3_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q3MIN7] xref: UniProtKB:Q3MIN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016367 ! RGL3_HUMAN [Term] id: CCO:B0069913 name: RGL3_HUMAN-Phosphoserine508 def: "Protein RGL3_HUMAN with the residue 508 substituted with Phosphoserine" [UniProtKB:Q3MIN7] xref: UniProtKB:Q3MIN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016367 ! RGL3_HUMAN [Term] id: CCO:B0069914 name: RGL3_HUMAN-Phosphoserine512 def: "Protein RGL3_HUMAN with the residue 512 substituted with Phosphoserine" [UniProtKB:Q3MIN7] xref: UniProtKB:Q3MIN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016367 ! RGL3_HUMAN [Term] id: CCO:B0069915 name: RGL3_HUMAN-Phosphoserine569 def: "Protein RGL3_HUMAN with the residue 569 substituted with Phosphoserine" [UniProtKB:Q3MIN7] comment: By similarity xref: UniProtKB:Q3MIN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0016367 ! RGL3_HUMAN [Term] id: CCO:B0069916 name: RGL3_HUMAN-Phosphoserine573 def: "Protein RGL3_HUMAN with the residue 573 substituted with Phosphoserine" [UniProtKB:Q3MIN7] comment: By similarity xref: UniProtKB:Q3MIN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0016367 ! RGL3_HUMAN [Term] id: CCO:B0069917 name: RGNEF_HUMAN-Phosphoserine624 def: "Protein RGNEF_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:Q8N1W1] xref: UniProtKB:Q8N1W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057433 ! RGNEF_HUMAN [Term] id: CCO:B0069918 name: RGN_HUMAN-Phosphoserine3 def: "Protein RGN_HUMAN with the residue 3 substituted with Phosphoserine" [UniProtKB:Q15493] comment: By similarity xref: UniProtKB:Q15493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056070 ! RGN_HUMAN [Term] id: CCO:B0069919 name: RGPS2_HUMAN-Phosphoserine311 def: "Protein RGPS2_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q86X27] xref: UniProtKB:Q86X27 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037994 ! RGPS2_HUMAN [Term] id: CCO:B0069920 name: RGRF1_HUMAN-Phosphoserine739 def: "Protein RGRF1_HUMAN with the residue 739 substituted with Phosphoserine" [UniProtKB:Q13972] comment: By similarity xref: UniProtKB:Q13972 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055954 ! RGRF1_HUMAN [Term] id: CCO:B0069921 name: RGRF2_HUMAN-Phosphoserine737 def: "Protein RGRF2_HUMAN with the residue 737 substituted with Phosphoserine" [UniProtKB:O14827] comment: by CDK5; xref: UniProtKB:O14827 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054381 ! RGRF2_HUMAN [Term] id: CCO:B0069922 name: RGS7_HUMAN-Phosphoserine229 def: "Protein RGS7_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:P49802] comment: By similarity xref: UniProtKB:P49802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0003112 ! regulator of G-protein signaling activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000402 ! heterotrimeric G-protein complex relationship: transformation_of CCO:B0055438 ! RGS7_HUMAN [Term] id: CCO:B0069923 name: RGS7_HUMAN-Phosphoserine434 def: "Protein RGS7_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:P49802] xref: UniProtKB:P49802 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055438 ! RGS7_HUMAN [Term] id: CCO:B0069924 name: RH10L_HUMAN-Phosphotyrosine378 def: "Protein RH10L_HUMAN with the residue 378 substituted with Phosphotyrosine" [UniProtKB:A6NI28] xref: UniProtKB:A6NI28 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053857 ! RH10L_HUMAN [Term] id: CCO:B0069925 name: RHBT1_HUMAN-Phosphoserine480 def: "Protein RHBT1_HUMAN with the residue 480 substituted with Phosphoserine" [UniProtKB:O94844] xref: UniProtKB:O94844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054704 ! RHBT1_HUMAN [Term] id: CCO:B0069926 name: RHBT1_HUMAN-Phosphothreonine483 def: "Protein RHBT1_HUMAN with the residue 483 substituted with Phosphothreonine" [UniProtKB:O94844] xref: UniProtKB:O94844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054704 ! RHBT1_HUMAN [Term] id: CCO:B0069927 name: RHES_HUMAN-Cysteine methyl ester263 def: "Protein RHES_HUMAN with the residue 263 substituted with Cysteine methyl ester" [UniProtKB:Q96D21] comment: By similarity xref: UniProtKB:Q96D21 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058189 ! RHES_HUMAN [Term] id: CCO:B0069928 name: RHG01_HUMAN-Phosphoserine51 def: "Protein RHG01_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q07960] xref: UniProtKB:Q07960 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055787 ! RHG01_HUMAN [Term] id: CCO:B0069929 name: RHG01_HUMAN-Phosphotyrosine65 def: "Protein RHG01_HUMAN with the residue 65 substituted with Phosphotyrosine" [UniProtKB:Q07960] comment: By similarity xref: UniProtKB:Q07960 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004517 ! Rac GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0055787 ! RHG01_HUMAN [Term] id: CCO:B0069930 name: RHG04_HUMAN-Phosphotyrosine171 def: "Protein RHG04_HUMAN with the residue 171 substituted with Phosphotyrosine" [UniProtKB:P98171] xref: UniProtKB:P98171 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055675 ! RHG04_HUMAN [Term] id: CCO:B0069931 name: RHG05_HUMAN-Phosphoserine968 def: "Protein RHG05_HUMAN with the residue 968 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069932 name: RHG05_HUMAN-Phosphoserine1115 def: "Protein RHG05_HUMAN with the residue 1115 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069933 name: RHG05_HUMAN-Phosphoserine1124 def: "Protein RHG05_HUMAN with the residue 1124 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069934 name: RHG05_HUMAN-Phosphothreonine1129 def: "Protein RHG05_HUMAN with the residue 1129 substituted with Phosphothreonine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069935 name: RHG05_HUMAN-Phosphoserine1138 def: "Protein RHG05_HUMAN with the residue 1138 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069936 name: RHG05_HUMAN-Phosphoserine1173 def: "Protein RHG05_HUMAN with the residue 1173 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069937 name: RHG05_HUMAN-Phosphoserine1176 def: "Protein RHG05_HUMAN with the residue 1176 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069938 name: RHG05_HUMAN-Phosphoserine1195 def: "Protein RHG05_HUMAN with the residue 1195 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069939 name: RHG05_HUMAN-Phosphoserine1202 def: "Protein RHG05_HUMAN with the residue 1202 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069940 name: RHG05_HUMAN-Phosphoserine1218 def: "Protein RHG05_HUMAN with the residue 1218 substituted with Phosphoserine" [UniProtKB:Q13017] xref: UniProtKB:Q13017 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019383 ! RHG05_HUMAN [Term] id: CCO:B0069941 name: RHG06_HUMAN-Phosphoserine264 def: "Protein RHG06_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:O43182] xref: UniProtKB:O43182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054455 ! RHG06_HUMAN [Term] id: CCO:B0069942 name: RHG06_HUMAN-Phosphoserine663 def: "Protein RHG06_HUMAN with the residue 663 substituted with Phosphoserine" [UniProtKB:O43182] xref: UniProtKB:O43182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054455 ! RHG06_HUMAN [Term] id: CCO:B0069943 name: RHG06_HUMAN-Phosphoserine673 def: "Protein RHG06_HUMAN with the residue 673 substituted with Phosphoserine" [UniProtKB:O43182] xref: UniProtKB:O43182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054455 ! RHG06_HUMAN [Term] id: CCO:B0069944 name: RHG06_HUMAN-Phosphoserine754 def: "Protein RHG06_HUMAN with the residue 754 substituted with Phosphoserine" [UniProtKB:O43182] xref: UniProtKB:O43182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000442 ! actin filament relationship: transformation_of CCO:B0054455 ! RHG06_HUMAN [Term] id: CCO:B0069945 name: RHG06_HUMAN-Phosphoserine777 def: "Protein RHG06_HUMAN with the residue 777 substituted with Phosphoserine" [UniProtKB:O43182] xref: UniProtKB:O43182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054455 ! RHG06_HUMAN [Term] id: CCO:B0069946 name: RHG06_HUMAN-Phosphoserine928 def: "Protein RHG06_HUMAN with the residue 928 substituted with Phosphoserine" [UniProtKB:O43182] xref: UniProtKB:O43182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054455 ! RHG06_HUMAN [Term] id: CCO:B0069947 name: RHG06_HUMAN-Phosphoserine939 def: "Protein RHG06_HUMAN with the residue 939 substituted with Phosphoserine" [UniProtKB:O43182] xref: UniProtKB:O43182 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054455 ! RHG06_HUMAN [Term] id: CCO:B0069948 name: RHG10_HUMAN-Phosphothreonine109 def: "Protein RHG10_HUMAN with the residue 109 substituted with Phosphothreonine" [UniProtKB:A1A4S6] comment: By similarity xref: UniProtKB:A1A4S6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053705 ! RHG10_HUMAN [Term] id: CCO:B0069949 name: RHG10_HUMAN-Phosphothreonine111 def: "Protein RHG10_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:A1A4S6] comment: By similarity xref: UniProtKB:A1A4S6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053705 ! RHG10_HUMAN [Term] id: CCO:B0069950 name: RHG12_HUMAN-Phosphoserine213 def: "Protein RHG12_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0069951 name: RHG12_HUMAN-Phosphoserine215 def: "Protein RHG12_HUMAN with the residue 215 substituted with Phosphoserine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0069952 name: RHG12_HUMAN-Phosphothreonine230 def: "Protein RHG12_HUMAN with the residue 230 substituted with Phosphothreonine" [UniProtKB:Q8IWW6] xref: UniProtKB:Q8IWW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041376 ! RHG12_HUMAN [Term] id: CCO:B0069953 name: RHG17_HUMAN-Phosphoserine161 def: "Protein RHG17_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q68EM7] comment: By similarity xref: UniProtKB:Q68EM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019132 ! RHG17_HUMAN [Term] id: CCO:B0069954 name: RHG17_HUMAN-Phosphoserine575 def: "Protein RHG17_HUMAN with the residue 575 substituted with Phosphoserine" [UniProtKB:Q68EM7] xref: UniProtKB:Q68EM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019132 ! RHG17_HUMAN [Term] id: CCO:B0069955 name: RHG19_HUMAN-Phosphoserine422 def: "Protein RHG19_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q14CB8] xref: UniProtKB:Q14CB8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056033 ! RHG19_HUMAN [Term] id: CCO:B0069956 name: RHG21_HUMAN-Phosphoserine35 def: "Protein RHG21_HUMAN with the residue 35 substituted with Phosphoserine" [UniProtKB:Q5T5U3] comment: By similarity xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069957 name: RHG21_HUMAN-Phosphoserine458 def: "Protein RHG21_HUMAN with the residue 458 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069958 name: RHG21_HUMAN-Phosphoserine474 def: "Protein RHG21_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069959 name: RHG21_HUMAN-Phosphoserine476 def: "Protein RHG21_HUMAN with the residue 476 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069960 name: RHG21_HUMAN-Phosphoserine923 def: "Protein RHG21_HUMAN with the residue 923 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069961 name: RHG21_HUMAN-Phosphoserine1089 def: "Protein RHG21_HUMAN with the residue 1089 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069962 name: RHG21_HUMAN-Phosphoserine1098 def: "Protein RHG21_HUMAN with the residue 1098 substituted with Phosphoserine" [UniProtKB:Q5T5U3] comment: By similarity xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069963 name: RHG21_HUMAN-Phosphoserine1219 def: "Protein RHG21_HUMAN with the residue 1219 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069964 name: RHG21_HUMAN-Phosphoserine1220 def: "Protein RHG21_HUMAN with the residue 1220 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069965 name: RHG21_HUMAN-Phosphotyrosine1239 def: "Protein RHG21_HUMAN with the residue 1239 substituted with Phosphotyrosine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069966 name: RHG21_HUMAN-Phosphothreonine1282 def: "Protein RHG21_HUMAN with the residue 1282 substituted with Phosphothreonine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069967 name: RHG21_HUMAN-Phosphoserine1377 def: "Protein RHG21_HUMAN with the residue 1377 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069968 name: RHG21_HUMAN-Phosphoserine1382 def: "Protein RHG21_HUMAN with the residue 1382 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069969 name: RHG21_HUMAN-Phosphoserine1430 def: "Protein RHG21_HUMAN with the residue 1430 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069970 name: RHG21_HUMAN-Phosphoserine1431 def: "Protein RHG21_HUMAN with the residue 1431 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069971 name: RHG21_HUMAN-Phosphoserine1432 def: "Protein RHG21_HUMAN with the residue 1432 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069972 name: RHG21_HUMAN-Phosphoserine1526 def: "Protein RHG21_HUMAN with the residue 1526 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069973 name: RHG21_HUMAN-Phosphoserine1668 def: "Protein RHG21_HUMAN with the residue 1668 substituted with Phosphoserine" [UniProtKB:Q5T5U3] xref: UniProtKB:Q5T5U3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056584 ! RHG21_HUMAN [Term] id: CCO:B0069974 name: RHG23_HUMAN-Phosphoserine361 def: "Protein RHG23_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9P227] xref: UniProtKB:Q9P227 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059051 ! RHG23_HUMAN [Term] id: CCO:B0069975 name: RHG23_HUMAN-Phosphoserine372 def: "Protein RHG23_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q9P227] xref: UniProtKB:Q9P227 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0059051 ! RHG23_HUMAN [Term] id: CCO:B0069976 name: RHG23_HUMAN-Phosphoserine423 def: "Protein RHG23_HUMAN with the residue 423 substituted with Phosphoserine" [UniProtKB:Q9P227] xref: UniProtKB:Q9P227 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059051 ! RHG23_HUMAN [Term] id: CCO:B0069977 name: RHG24_HUMAN-Phosphoserine391 def: "Protein RHG24_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q8N264] xref: UniProtKB:Q8N264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:B0069978 name: RHG24_HUMAN-Phosphoserine402 def: "Protein RHG24_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:Q8N264] xref: UniProtKB:Q8N264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:B0069979 name: RHG24_HUMAN-Phosphoserine413 def: "Protein RHG24_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q8N264] xref: UniProtKB:Q8N264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:B0069980 name: RHG24_HUMAN-Phosphoserine415 def: "Protein RHG24_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q8N264] xref: UniProtKB:Q8N264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:B0069981 name: RHG24_HUMAN-Phosphoserine437 def: "Protein RHG24_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q8N264] xref: UniProtKB:Q8N264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:B0069982 name: RHG24_HUMAN-Phosphothreonine452 def: "Protein RHG24_HUMAN with the residue 452 substituted with Phosphothreonine" [UniProtKB:Q8N264] xref: UniProtKB:Q8N264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:B0069983 name: RHG25_HUMAN-Phosphoserine400 def: "Protein RHG25_HUMAN with the residue 400 substituted with Phosphoserine" [UniProtKB:P42331] comment: By similarity xref: UniProtKB:P42331 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0055349 ! RHG25_HUMAN [Term] id: CCO:B0069984 name: RHG29_HUMAN-Phosphoserine171 def: "Protein RHG29_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069985 name: RHG29_HUMAN-Phosphoserine176 def: "Protein RHG29_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069986 name: RHG29_HUMAN-Phosphoserine179 def: "Protein RHG29_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069987 name: RHG29_HUMAN-Phosphoserine190 def: "Protein RHG29_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069988 name: RHG29_HUMAN-Phosphoserine913 def: "Protein RHG29_HUMAN with the residue 913 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069989 name: RHG29_HUMAN-Phosphoserine949 def: "Protein RHG29_HUMAN with the residue 949 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069990 name: RHG29_HUMAN-Phosphoserine1019 def: "Protein RHG29_HUMAN with the residue 1019 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069991 name: RHG29_HUMAN-Phosphoserine1029 def: "Protein RHG29_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069992 name: RHG29_HUMAN-Phosphoserine1146 def: "Protein RHG29_HUMAN with the residue 1146 substituted with Phosphoserine" [UniProtKB:Q52LW3] xref: UniProtKB:Q52LW3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056343 ! RHG29_HUMAN [Term] id: CCO:B0069993 name: RHG30_HUMAN-Phosphoserine987 def: "Protein RHG30_HUMAN with the residue 987 substituted with Phosphoserine" [UniProtKB:Q7Z6I6] xref: UniProtKB:Q7Z6I6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057197 ! RHG30_HUMAN [Term] id: CCO:B0069994 name: RHG30_HUMAN-Phosphoserine988 def: "Protein RHG30_HUMAN with the residue 988 substituted with Phosphoserine" [UniProtKB:Q7Z6I6] xref: UniProtKB:Q7Z6I6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057197 ! RHG30_HUMAN [Term] id: CCO:B0069995 name: RHG30_HUMAN-Phosphoserine996 def: "Protein RHG30_HUMAN with the residue 996 substituted with Phosphoserine" [UniProtKB:Q7Z6I6] xref: UniProtKB:Q7Z6I6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057197 ! RHG30_HUMAN [Term] id: CCO:B0069996 name: RHG30_HUMAN-Phosphotyrosine1087 def: "Protein RHG30_HUMAN with the residue 1087 substituted with Phosphotyrosine" [UniProtKB:Q7Z6I6] xref: UniProtKB:Q7Z6I6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057197 ! RHG30_HUMAN [Term] id: CCO:B0069997 name: RHGBA_HUMAN-Phosphoserine285 def: "Protein RHGBA_HUMAN with the residue 285 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0069998 name: RHGBA_HUMAN-Phosphoserine316 def: "Protein RHGBA_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0069999 name: RHGBA_HUMAN-Phosphoserine318 def: "Protein RHGBA_HUMAN with the residue 318 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070000 name: RHGBA_HUMAN-Phosphothreonine323 def: "Protein RHGBA_HUMAN with the residue 323 substituted with Phosphothreonine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070001 name: RHGBA_HUMAN-Phosphoserine339 def: "Protein RHGBA_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070002 name: RHGBA_HUMAN-Phosphoserine340 def: "Protein RHGBA_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070003 name: RHGBA_HUMAN-Phosphoserine415 def: "Protein RHGBA_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070004 name: RHGBA_HUMAN-Phosphoserine422 def: "Protein RHGBA_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070005 name: RHGBA_HUMAN-Phosphoserine484 def: "Protein RHGBA_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070006 name: RHGBA_HUMAN-Phosphothreonine508 def: "Protein RHGBA_HUMAN with the residue 508 substituted with Phosphothreonine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070007 name: RHGBA_HUMAN-Phosphoserine582 def: "Protein RHGBA_HUMAN with the residue 582 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070008 name: RHGBA_HUMAN-Phosphoserine585 def: "Protein RHGBA_HUMAN with the residue 585 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070009 name: RHGBA_HUMAN-Phosphoserine675 def: "Protein RHGBA_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:Q6P4F7] xref: UniProtKB:Q6P4F7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056889 ! RHGBA_HUMAN [Term] id: CCO:B0070010 name: RHOD_HUMAN-Cysteine methyl ester207 def: "Protein RHOD_HUMAN with the residue 207 substituted with Cysteine methyl ester" [UniProtKB:O00212] comment: By similarity xref: UniProtKB:O00212 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054300 ! RHOD_HUMAN [Term] id: CCO:B0070011 name: RHOF_HUMAN-Cysteine methyl ester208 def: "Protein RHOF_HUMAN with the residue 208 substituted with Cysteine methyl ester" [UniProtKB:Q9HBH0] comment: Potential xref: UniProtKB:Q9HBH0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058784 ! RHOF_HUMAN [Term] id: CCO:B0070012 name: RHOH_HUMAN-Cysteine methyl ester188 def: "Protein RHOH_HUMAN with the residue 188 substituted with Cysteine methyl ester" [UniProtKB:Q15669] comment: By similarity xref: UniProtKB:Q15669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003531 ! Rho GTPase binding relationship: has_function CCO:F0004133 ! kinase inhibitor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056094 ! RHOH_HUMAN [Term] id: CCO:B0070013 name: RHOJ_HUMAN-Cysteine methyl ester211 def: "Protein RHOJ_HUMAN with the residue 211 substituted with Cysteine methyl ester" [UniProtKB:Q9H4E5] comment: By similarity xref: UniProtKB:Q9H4E5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058716 ! RHOJ_HUMAN [Term] id: CCO:B0070014 name: RHOQ_HUMAN-Cysteine methyl ester202 def: "Protein RHOQ_HUMAN with the residue 202 substituted with Cysteine methyl ester" [UniProtKB:P17081] comment: By similarity xref: UniProtKB:P17081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055081 ! RHOQ_HUMAN [Term] id: CCO:B0070015 name: RHPN2_HUMAN-Nitrated tyrosine258 def: "Protein RHPN2_HUMAN with the residue 258 substituted with Nitrated tyrosine" [UniProtKB:Q8IUC4] xref: UniProtKB:Q8IUC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057320 ! RHPN2_HUMAN [Term] id: CCO:B0070016 name: RHPN2_HUMAN-Phosphoserine639 def: "Protein RHPN2_HUMAN with the residue 639 substituted with Phosphoserine" [UniProtKB:Q8IUC4] xref: UniProtKB:Q8IUC4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057320 ! RHPN2_HUMAN [Term] id: CCO:B0070017 name: RICH2_HUMAN-Phosphoserine514 def: "Protein RICH2_HUMAN with the residue 514 substituted with Phosphoserine" [UniProtKB:Q17R89] xref: UniProtKB:Q17R89 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0019135 ! RICH2_HUMAN [Term] id: CCO:B0070018 name: RICS_HUMAN-Phosphoserine856 def: "Protein RICS_HUMAN with the residue 856 substituted with Phosphoserine" [UniProtKB:A7KAX9] comment: By similarity xref: UniProtKB:A7KAX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053947 ! RICS_HUMAN [Term] id: CCO:B0070019 name: RICS_HUMAN-Phosphoserine892 def: "Protein RICS_HUMAN with the residue 892 substituted with Phosphoserine" [UniProtKB:A7KAX9] comment: By similarity xref: UniProtKB:A7KAX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053947 ! RICS_HUMAN [Term] id: CCO:B0070020 name: RICS_HUMAN-Phosphoserine952 def: "Protein RICS_HUMAN with the residue 952 substituted with Phosphoserine" [UniProtKB:A7KAX9] comment: By similarity xref: UniProtKB:A7KAX9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0053947 ! RICS_HUMAN [Term] id: CCO:B0070021 name: RICTR_HUMAN-Phosphoserine1282 def: "Protein RICTR_HUMAN with the residue 1282 substituted with Phosphoserine" [UniProtKB:Q6R327] xref: UniProtKB:Q6R327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048930 ! RICTR_HUMAN [Term] id: CCO:B0070022 name: RICTR_HUMAN-Phosphotyrosine1386 def: "Protein RICTR_HUMAN with the residue 1386 substituted with Phosphotyrosine" [UniProtKB:Q6R327] xref: UniProtKB:Q6R327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048930 ! RICTR_HUMAN [Term] id: CCO:B0070023 name: RICTR_HUMAN-Phosphoserine1388 def: "Protein RICTR_HUMAN with the residue 1388 substituted with Phosphoserine" [UniProtKB:Q6R327] xref: UniProtKB:Q6R327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0002068 ! TORC2 complex relationship: transformation_of CCO:B0048930 ! RICTR_HUMAN [Term] id: CCO:B0070024 name: RICTR_HUMAN-Phosphoserine1396 def: "Protein RICTR_HUMAN with the residue 1396 substituted with Phosphoserine" [UniProtKB:Q6R327] xref: UniProtKB:Q6R327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048930 ! RICTR_HUMAN [Term] id: CCO:B0070025 name: RIF1_HUMAN-Phosphoserine402 def: "Protein RIF1_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070026 name: RIF1_HUMAN-Phosphothreonine409 def: "Protein RIF1_HUMAN with the residue 409 substituted with Phosphothreonine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070027 name: RIF1_HUMAN-Phosphoserine1162 def: "Protein RIF1_HUMAN with the residue 1162 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070028 name: RIF1_HUMAN-Phosphoserine1236 def: "Protein RIF1_HUMAN with the residue 1236 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070029 name: RIF1_HUMAN-Phosphoserine1238 def: "Protein RIF1_HUMAN with the residue 1238 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070030 name: RIF1_HUMAN-Phosphoserine1422 def: "Protein RIF1_HUMAN with the residue 1422 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070031 name: RIF1_HUMAN-Phosphoserine1552 def: "Protein RIF1_HUMAN with the residue 1552 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070032 name: RIF1_HUMAN-Phosphoserine1554 def: "Protein RIF1_HUMAN with the residue 1554 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070033 name: RIF1_HUMAN-Phosphoserine1576 def: "Protein RIF1_HUMAN with the residue 1576 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070034 name: RIF1_HUMAN-Phosphoserine1616 def: "Protein RIF1_HUMAN with the residue 1616 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070035 name: RIF1_HUMAN-Phosphoserine1693 def: "Protein RIF1_HUMAN with the residue 1693 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070036 name: RIF1_HUMAN-Phosphoserine1810 def: "Protein RIF1_HUMAN with the residue 1810 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070037 name: RIF1_HUMAN-Phosphoserine2144 def: "Protein RIF1_HUMAN with the residue 2144 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070038 name: RIF1_HUMAN-Phosphoserine2172 def: "Protein RIF1_HUMAN with the residue 2172 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070039 name: RIF1_HUMAN-Phosphoserine2176 def: "Protein RIF1_HUMAN with the residue 2176 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000190 ! female pronucleus relationship: located_in CCO:C0000191 ! male pronucleus relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070040 name: RIF1_HUMAN-Phosphoserine2196 def: "Protein RIF1_HUMAN with the residue 2196 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070041 name: RIF1_HUMAN-Phosphoserine2205 def: "Protein RIF1_HUMAN with the residue 2205 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070042 name: RIF1_HUMAN-Phosphoserine2260 def: "Protein RIF1_HUMAN with the residue 2260 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070043 name: RIF1_HUMAN-Phosphoserine2265 def: "Protein RIF1_HUMAN with the residue 2265 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070044 name: RIF1_HUMAN-Phosphoserine2339 def: "Protein RIF1_HUMAN with the residue 2339 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070045 name: RIF1_HUMAN-Phosphoserine2391 def: "Protein RIF1_HUMAN with the residue 2391 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070046 name: RIF1_HUMAN-Phosphoserine2393 def: "Protein RIF1_HUMAN with the residue 2393 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070047 name: RIF1_HUMAN-Phosphoserine2465 def: "Protein RIF1_HUMAN with the residue 2465 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070048 name: RIF1_HUMAN-Phosphoserine2471 def: "Protein RIF1_HUMAN with the residue 2471 substituted with Phosphoserine" [UniProtKB:Q5UIP0] xref: UniProtKB:Q5UIP0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:B0070049 name: RIN1_HUMAN-Phosphoserine210 def: "Protein RIN1_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0070050 name: RIN1_HUMAN-Phosphothreonine251 def: "Protein RIN1_HUMAN with the residue 251 substituted with Phosphothreonine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0070051 name: RIN1_HUMAN-Phosphoserine258 def: "Protein RIN1_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0070052 name: RIN1_HUMAN-Phosphoserine609 def: "Protein RIN1_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:Q13671] xref: UniProtKB:Q13671 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:B0070053 name: RIN2_HUMAN-Phosphoserine501 def: "Protein RIN2_HUMAN with the residue 501 substituted with Phosphoserine" [UniProtKB:Q8WYP3] comment: By similarity xref: UniProtKB:Q8WYP3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058047 ! RIN2_HUMAN [Term] id: CCO:B0070054 name: RIN2_HUMAN-Phosphothreonine509 def: "Protein RIN2_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q8WYP3] xref: UniProtKB:Q8WYP3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001388 ! small GTPase regulator activity relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003575 ! Rab guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058047 ! RIN2_HUMAN [Term] id: CCO:B0070055 name: RING1_HUMAN-Phosphoserine187 def: "Protein RING1_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:Q06587] xref: UniProtKB:Q06587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020553 ! RING1_HUMAN [Term] id: CCO:B0070056 name: RING1_HUMAN-Phosphoserine188 def: "Protein RING1_HUMAN with the residue 188 substituted with Phosphoserine" [UniProtKB:Q06587] xref: UniProtKB:Q06587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020553 ! RING1_HUMAN [Term] id: CCO:B0070057 name: RING1_HUMAN-Phosphoserine190 def: "Protein RING1_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q06587] xref: UniProtKB:Q06587 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020553 ! RING1_HUMAN [Term] id: CCO:B0070058 name: RIPK1_HUMAN-Phosphoserine320 def: "Protein RIPK1_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q13546] xref: UniProtKB:Q13546 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:B0070059 name: RK_HUMAN-Phosphoserine21 def: "Protein RK_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q15835] comment: by autocatalysis; By similarity xref: UniProtKB:Q15835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056115 ! RK_HUMAN [Term] id: CCO:B0070060 name: RK_HUMAN-Phosphoserine491 def: "Protein RK_HUMAN with the residue 491 substituted with Phosphoserine" [UniProtKB:Q15835] comment: by autocatalysis; By similarity xref: UniProtKB:Q15835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056115 ! RK_HUMAN [Term] id: CCO:B0070061 name: RK_HUMAN-Phosphothreonine492 def: "Protein RK_HUMAN with the residue 492 substituted with Phosphothreonine" [UniProtKB:Q15835] comment: by autocatalysis; By similarity xref: UniProtKB:Q15835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056115 ! RK_HUMAN [Term] id: CCO:B0070062 name: RK_HUMAN-Cysteine methyl ester560 def: "Protein RK_HUMAN with the residue 560 substituted with Cysteine methyl ester" [UniProtKB:Q15835] comment: By similarity xref: UniProtKB:Q15835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001069 ! G-protein coupled receptor kinase activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0007606 ! rhodopsin kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056115 ! RK_HUMAN [Term] id: CCO:B0070063 name: RL14_HUMAN-Phosphoserine139 def: "Protein RL14_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:P50914] xref: UniProtKB:P50914 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0063090 ! RL14_HUMAN [Term] id: CCO:B0070064 name: RL15_HUMAN-Phosphoserine97 def: "Protein RL15_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:P61313] xref: UniProtKB:P61313 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005857 ! RL15_HUMAN [Term] id: CCO:B0070065 name: RL18A_HUMAN-Phosphoserine123 def: "Protein RL18A_HUMAN with the residue 123 substituted with Phosphoserine" [UniProtKB:Q02543] xref: UniProtKB:Q02543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006300 ! RL18A_HUMAN [Term] id: CCO:B0070066 name: RL18_HUMAN-Phosphothreonine158 def: "Protein RL18_HUMAN with the residue 158 substituted with Phosphothreonine" [UniProtKB:Q07020] xref: UniProtKB:Q07020 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005741 ! RL18_HUMAN [Term] id: CCO:B0070067 name: RL1D1_HUMAN-Phosphothreonine340 def: "Protein RL1D1_HUMAN with the residue 340 substituted with Phosphothreonine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070068 name: RL1D1_HUMAN-Phosphothreonine358 def: "Protein RL1D1_HUMAN with the residue 358 substituted with Phosphothreonine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000407 ! ribosome relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070069 name: RL1D1_HUMAN-Phosphoserine361 def: "Protein RL1D1_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070070 name: RL1D1_HUMAN-Phosphoserine392 def: "Protein RL1D1_HUMAN with the residue 392 substituted with Phosphoserine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070071 name: RL1D1_HUMAN-Phosphoserine396 def: "Protein RL1D1_HUMAN with the residue 396 substituted with Phosphoserine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070072 name: RL1D1_HUMAN-Phosphothreonine401 def: "Protein RL1D1_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070073 name: RL1D1_HUMAN-Phosphothreonine423 def: "Protein RL1D1_HUMAN with the residue 423 substituted with Phosphothreonine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070074 name: RL1D1_HUMAN-Phosphoserine427 def: "Protein RL1D1_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070075 name: RL1D1_HUMAN-Phosphoserine443 def: "Protein RL1D1_HUMAN with the residue 443 substituted with Phosphoserine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070076 name: RL1D1_HUMAN-Phosphothreonine465 def: "Protein RL1D1_HUMAN with the residue 465 substituted with Phosphothreonine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070077 name: RL1D1_HUMAN-Phosphoserine467 def: "Protein RL1D1_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:O76021] xref: UniProtKB:O76021 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:B0070078 name: RL23A_HUMAN-Phosphoserine43 def: "Protein RL23A_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:P62750] xref: UniProtKB:P62750 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063360 ! RL23A_HUMAN [Term] id: CCO:B0070079 name: RL26_HUMAN-Phosphothreonine139 def: "Protein RL26_HUMAN with the residue 139 substituted with Phosphothreonine" [UniProtKB:P61254] xref: UniProtKB:P61254 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000755 ! large ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0063367 ! RL26_HUMAN [Term] id: CCO:B0070080 name: RL29_HUMAN-N6-methyllysine5 def: "Protein RL29_HUMAN with the residue 5 substituted with N6-methyllysine" [UniProtKB:P47914] xref: UniProtKB:P47914 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0028895 ! RL29_HUMAN [Term] id: CCO:B0070081 name: RL29_HUMAN-Phosphoserine142 def: "Protein RL29_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:P47914] xref: UniProtKB:P47914 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028895 ! RL29_HUMAN [Term] id: CCO:B0070082 name: RL31_HUMAN-Phosphoserine98 def: "Protein RL31_HUMAN with the residue 98 substituted with Phosphoserine" [UniProtKB:P62899] xref: UniProtKB:P62899 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015391 ! RL31_HUMAN [Term] id: CCO:B0070083 name: RL31_HUMAN-Phosphotyrosine103 def: "Protein RL31_HUMAN with the residue 103 substituted with Phosphotyrosine" [UniProtKB:P62899] xref: UniProtKB:P62899 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015391 ! RL31_HUMAN [Term] id: CCO:B0070084 name: RL31_HUMAN-Phosphotyrosine108 def: "Protein RL31_HUMAN with the residue 108 substituted with Phosphotyrosine" [UniProtKB:P62899] xref: UniProtKB:P62899 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0015391 ! RL31_HUMAN [Term] id: CCO:B0070085 name: RL3_HUMAN-Phosphoserine13 def: "Protein RL3_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P39023] xref: UniProtKB:P39023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063083 ! RL3_HUMAN [Term] id: CCO:B0070086 name: RL3_HUMAN-Phosphotyrosine307 def: "Protein RL3_HUMAN with the residue 307 substituted with Phosphotyrosine" [UniProtKB:P39023] xref: UniProtKB:P39023 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063083 ! RL3_HUMAN [Term] id: CCO:B0070087 name: RL40_HUMAN-N6,N6,N6-trimethyllysine22 def: "Protein RL40_HUMAN with the residue 22 substituted with N6,N6,N6-trimethyllysine" [UniProtKB:P62987] comment: By similarity xref: UniProtKB:P62987 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063107 ! RL40_HUMAN [Term] id: CCO:B0070088 name: RL4_HUMAN-Phosphoserine365 def: "Protein RL4_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:P36578] xref: UniProtKB:P36578 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005861 ! RL4_HUMAN [Term] id: CCO:B0070089 name: RL5_HUMAN-Phosphoserine286 def: "Protein RL5_HUMAN with the residue 286 substituted with Phosphoserine" [UniProtKB:P46777] xref: UniProtKB:P46777 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001710 ! 5S rRNA binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: transformation_of CCO:B0063183 ! RL5_HUMAN [Term] id: CCO:B0070090 name: RL6_HUMAN-Phosphoserine127 def: "Protein RL6_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q02878] xref: UniProtKB:Q02878 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055717 ! RL6_HUMAN [Term] id: CCO:B0070091 name: RLF_HUMAN-Phosphoserine41 def: "Protein RLF_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q13129] xref: UniProtKB:Q13129 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055877 ! RLF_HUMAN [Term] id: CCO:B0070092 name: RM44_HUMAN-Phosphoserine251 def: "Protein RM44_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:Q9H9J2] comment: By similarity xref: UniProtKB:Q9H9J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063385 ! RM44_HUMAN [Term] id: CCO:B0070093 name: RM44_HUMAN-Phosphoserine255 def: "Protein RM44_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:Q9H9J2] comment: By similarity xref: UniProtKB:Q9H9J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063385 ! RM44_HUMAN [Term] id: CCO:B0070094 name: RMI1_HUMAN-Phosphoserine225 def: "Protein RMI1_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q9H9A7] xref: UniProtKB:Q9H9A7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:B0070095 name: RMP_HUMAN-Phosphothreonine241 def: "Protein RMP_HUMAN with the residue 241 substituted with Phosphothreonine" [UniProtKB:O94763] xref: UniProtKB:O94763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054697 ! RMP_HUMAN [Term] id: CCO:B0070096 name: RMP_HUMAN-Phosphothreonine242 def: "Protein RMP_HUMAN with the residue 242 substituted with Phosphothreonine" [UniProtKB:O94763] xref: UniProtKB:O94763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000777 ! prefoldin complex relationship: transformation_of CCO:B0054697 ! RMP_HUMAN [Term] id: CCO:B0070097 name: RMP_HUMAN-Phosphoserine243 def: "Protein RMP_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:O94763] xref: UniProtKB:O94763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054697 ! RMP_HUMAN [Term] id: CCO:B0070098 name: RMP_HUMAN-Phosphoserine244 def: "Protein RMP_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:O94763] xref: UniProtKB:O94763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054697 ! RMP_HUMAN [Term] id: CCO:B0070099 name: RMP_HUMAN-Phosphoserine439 def: "Protein RMP_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:O94763] comment: By similarity xref: UniProtKB:O94763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054697 ! RMP_HUMAN [Term] id: CCO:B0070100 name: RN138_HUMAN-Phosphoserine124 def: "Protein RN138_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q8WVD3] xref: UniProtKB:Q8WVD3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063219 ! RN138_HUMAN [Term] id: CCO:B0070101 name: RN139_HUMAN-Phosphoserine625 def: "Protein RN139_HUMAN with the residue 625 substituted with Phosphoserine" [UniProtKB:Q8WU17] xref: UniProtKB:Q8WU17 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057974 ! RN139_HUMAN [Term] id: CCO:B0070102 name: RN139_HUMAN-Phosphoserine634 def: "Protein RN139_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:Q8WU17] xref: UniProtKB:Q8WU17 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057974 ! RN139_HUMAN [Term] id: CCO:B0070103 name: RN139_HUMAN-Phosphothreonine635 def: "Protein RN139_HUMAN with the residue 635 substituted with Phosphothreonine" [UniProtKB:Q8WU17] xref: UniProtKB:Q8WU17 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057974 ! RN139_HUMAN [Term] id: CCO:B0070104 name: RN139_HUMAN-Phosphothreonine663 def: "Protein RN139_HUMAN with the residue 663 substituted with Phosphothreonine" [UniProtKB:Q8WU17] xref: UniProtKB:Q8WU17 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057974 ! RN139_HUMAN [Term] id: CCO:B0070105 name: RNF12_HUMAN-Phosphoserine228 def: "Protein RNF12_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q9NVW2] comment: By similarity xref: UniProtKB:Q9NVW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058934 ! RNF12_HUMAN [Term] id: CCO:B0070106 name: RNF12_HUMAN-Phosphoserine230 def: "Protein RNF12_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q9NVW2] comment: By similarity xref: UniProtKB:Q9NVW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058934 ! RNF12_HUMAN [Term] id: CCO:B0070107 name: RNF14_HUMAN-Phosphoserine348 def: "Protein RNF14_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:Q9UBS8] xref: UniProtKB:Q9UBS8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007990 ! androgen receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059083 ! RNF14_HUMAN [Term] id: CCO:B0070108 name: RNPS1_HUMAN-Phosphoserine27 def: "Protein RNPS1_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070109 name: RNPS1_HUMAN-Phosphoserine53 def: "Protein RNPS1_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q15287] comment: by CK2; xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070110 name: RNPS1_HUMAN-Phosphoserine125 def: "Protein RNPS1_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070111 name: RNPS1_HUMAN-Phosphoserine155 def: "Protein RNPS1_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070112 name: RNPS1_HUMAN-Phosphoserine157 def: "Protein RNPS1_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070113 name: RNPS1_HUMAN-Phosphotyrosine205 def: "Protein RNPS1_HUMAN with the residue 205 substituted with Phosphotyrosine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070114 name: RNPS1_HUMAN-Phosphoserine251 def: "Protein RNPS1_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070115 name: RNPS1_HUMAN-Phosphoserine266 def: "Protein RNPS1_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070116 name: RNPS1_HUMAN-Phosphoserine287 def: "Protein RNPS1_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070117 name: RNPS1_HUMAN-Phosphoserine289 def: "Protein RNPS1_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q15287] xref: UniProtKB:Q15287 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:B0070118 name: RNZ2_HUMAN-Phosphoserine199 def: "Protein RNZ2_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q9BQ52] xref: UniProtKB:Q9BQ52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000916 ! endonuclease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063441 ! RNZ2_HUMAN [Term] id: CCO:B0070119 name: RNZ2_HUMAN-Phosphoserine208 def: "Protein RNZ2_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q9BQ52] comment: By similarity xref: UniProtKB:Q9BQ52 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063441 ! RNZ2_HUMAN [Term] id: CCO:B0070120 name: ROA3_HUMAN-Phosphoserine366 def: "Protein ROA3_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:P51991] xref: UniProtKB:P51991 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0028239 ! ROA3_HUMAN [Term] id: CCO:B0070121 name: ROAA_HUMAN-Phosphoserine77 def: "Protein ROAA_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q99729] comment: By similarity xref: UniProtKB:Q99729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058447 ! ROAA_HUMAN [Term] id: CCO:B0070122 name: ROAA_HUMAN-Phosphoserine242 def: "Protein ROAA_HUMAN with the residue 242 substituted with Phosphoserine" [UniProtKB:Q99729] xref: UniProtKB:Q99729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058447 ! ROAA_HUMAN [Term] id: CCO:B0070123 name: ROAA_HUMAN-Omega-N-methylated arginine322 def: "Protein ROAA_HUMAN with the residue 322 substituted with Omega-N-methylated arginine" [UniProtKB:Q99729] xref: UniProtKB:Q99729 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058447 ! ROAA_HUMAN [Term] id: CCO:B0070124 name: ROBO1_HUMAN-Phosphoserine940 def: "Protein ROBO1_HUMAN with the residue 940 substituted with Phosphoserine" [UniProtKB:Q9Y6N7] xref: UniProtKB:Q9Y6N7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:B0070125 name: ROBO1_HUMAN-Phosphotyrosine1038 def: "Protein ROBO1_HUMAN with the residue 1038 substituted with Phosphotyrosine" [UniProtKB:Q9Y6N7] comment: by ABL; in vitro; xref: UniProtKB:Q9Y6N7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001690 ! axon guidance receptor activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:B0070126 name: ROBO1_HUMAN-Phosphoserine1055 def: "Protein ROBO1_HUMAN with the residue 1055 substituted with Phosphoserine" [UniProtKB:Q9Y6N7] xref: UniProtKB:Q9Y6N7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:B0070127 name: ROBO1_HUMAN-Phosphotyrosine1073 def: "Protein ROBO1_HUMAN with the residue 1073 substituted with Phosphotyrosine" [UniProtKB:Q9Y6N7] comment: by ABL; in vitro; xref: UniProtKB:Q9Y6N7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:B0070128 name: ROBO1_HUMAN-Phosphotyrosine1114 def: "Protein ROBO1_HUMAN with the residue 1114 substituted with Phosphotyrosine" [UniProtKB:Q9Y6N7] comment: by ABL; in vitro; xref: UniProtKB:Q9Y6N7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:B0070129 name: ROBO1_HUMAN-Phosphothreonine1240 def: "Protein ROBO1_HUMAN with the residue 1240 substituted with Phosphothreonine" [UniProtKB:Q9Y6N7] xref: UniProtKB:Q9Y6N7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:B0070130 name: ROCK1_HUMAN-Phosphothreonine455 def: "Protein ROCK1_HUMAN with the residue 455 substituted with Phosphothreonine" [UniProtKB:Q13464] xref: UniProtKB:Q13464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055910 ! ROCK1_HUMAN [Term] id: CCO:B0070131 name: ROCK1_HUMAN-Phosphoserine456 def: "Protein ROCK1_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:Q13464] xref: UniProtKB:Q13464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055910 ! ROCK1_HUMAN [Term] id: CCO:B0070132 name: ROCK1_HUMAN-Phosphothreonine1180 def: "Protein ROCK1_HUMAN with the residue 1180 substituted with Phosphothreonine" [UniProtKB:Q13464] xref: UniProtKB:Q13464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055910 ! ROCK1_HUMAN [Term] id: CCO:B0070133 name: ROCK2_HUMAN-Phosphothreonine1078 def: "Protein ROCK2_HUMAN with the residue 1078 substituted with Phosphothreonine" [UniProtKB:O75116] xref: UniProtKB:O75116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054602 ! ROCK2_HUMAN [Term] id: CCO:B0070134 name: ROCK2_HUMAN-Phosphoserine1134 def: "Protein ROCK2_HUMAN with the residue 1134 substituted with Phosphoserine" [UniProtKB:O75116] xref: UniProtKB:O75116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054602 ! ROCK2_HUMAN [Term] id: CCO:B0070135 name: ROCK2_HUMAN-Phosphoserine1137 def: "Protein ROCK2_HUMAN with the residue 1137 substituted with Phosphoserine" [UniProtKB:O75116] xref: UniProtKB:O75116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054602 ! ROCK2_HUMAN [Term] id: CCO:B0070136 name: ROCK2_HUMAN-Phosphoserine1362 def: "Protein ROCK2_HUMAN with the residue 1362 substituted with Phosphoserine" [UniProtKB:O75116] xref: UniProtKB:O75116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054602 ! ROCK2_HUMAN [Term] id: CCO:B0070137 name: ROCK2_HUMAN-Phosphoserine1374 def: "Protein ROCK2_HUMAN with the residue 1374 substituted with Phosphoserine" [UniProtKB:O75116] xref: UniProtKB:O75116 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054602 ! ROCK2_HUMAN [Term] id: CCO:B0070138 name: RON_HUMAN-Phosphotyrosine1353 def: "Protein RON_HUMAN with the residue 1353 substituted with Phosphotyrosine" [UniProtKB:Q04912] comment: by autocatalysis; By similarity xref: UniProtKB:Q04912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055739 ! RON_HUMAN [Term] id: CCO:B0070139 name: RON_HUMAN-Phosphotyrosine1360 def: "Protein RON_HUMAN with the residue 1360 substituted with Phosphotyrosine" [UniProtKB:Q04912] comment: by autocatalysis; By similarity xref: UniProtKB:Q04912 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001348 ! macrophage colony stimulating factor receptor activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055739 ! RON_HUMAN [Term] id: CCO:B0070140 name: ROR1_HUMAN-Phosphotyrosine645 def: "Protein ROR1_HUMAN with the residue 645 substituted with Phosphotyrosine" [UniProtKB:Q01973] comment: by autocatalysis; By similarity xref: UniProtKB:Q01973 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055699 ! ROR1_HUMAN [Term] id: CCO:B0070141 name: ROR2_HUMAN-Phosphoserine449 def: "Protein ROR2_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q01974] xref: UniProtKB:Q01974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055700 ! ROR2_HUMAN [Term] id: CCO:B0070142 name: ROR2_HUMAN-Sulfoserine469 def: "Protein ROR2_HUMAN with the residue 469 substituted with Sulfoserine" [UniProtKB:Q01974] comment: partial; xref: UniProtKB:Q01974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055700 ! ROR2_HUMAN [Term] id: CCO:B0070143 name: ROR2_HUMAN-Sulfoserine471 def: "Protein ROR2_HUMAN with the residue 471 substituted with Sulfoserine" [UniProtKB:Q01974] comment: partial; xref: UniProtKB:Q01974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055700 ! ROR2_HUMAN [Term] id: CCO:B0070144 name: ROR2_HUMAN-Phosphotyrosine646 def: "Protein ROR2_HUMAN with the residue 646 substituted with Phosphotyrosine" [UniProtKB:Q01974] comment: by autocatalysis; By similarity xref: UniProtKB:Q01974 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055700 ! ROR2_HUMAN [Term] id: CCO:B0070145 name: RPA1_HUMAN-Phosphothreonine1580 def: "Protein RPA1_HUMAN with the residue 1580 substituted with Phosphothreonine" [UniProtKB:O95602] xref: UniProtKB:O95602 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063137 ! RPA1_HUMAN [Term] id: CCO:B0070146 name: RPA34_HUMAN-Phosphotyrosine80 def: "Protein RPA34_HUMAN with the residue 80 substituted with Phosphotyrosine" [UniProtKB:O15446] xref: UniProtKB:O15446 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000010 ! RNA polymerase I transcription factor complex relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: located_in CCO:C0000323 ! DNA-directed RNA polymerase I complex relationship: transformation_of CCO:B0054437 ! RPA34_HUMAN [Term] id: CCO:B0070147 name: RPA34_HUMAN-Phosphoserine172 def: "Protein RPA34_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:O15446] xref: UniProtKB:O15446 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054437 ! RPA34_HUMAN [Term] id: CCO:B0070148 name: RPA34_HUMAN-Phosphoserine309 def: "Protein RPA34_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:O15446] xref: UniProtKB:O15446 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054437 ! RPA34_HUMAN [Term] id: CCO:B0070149 name: RPA49_HUMAN-Phosphoserine225 def: "Protein RPA49_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q9GZS1] xref: UniProtKB:Q9GZS1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0063135 ! RPA49_HUMAN [Term] id: CCO:B0070150 name: RPAB2_HUMAN-Phosphoserine2 def: "Protein RPAB2_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P61218] comment: by CK2; By similarity xref: UniProtKB:P61218 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0001068 ! RNA polymerase complex relationship: transformation_of CCO:B0055606 ! RPAB2_HUMAN [Term] id: CCO:B0070151 name: RPAB3_HUMAN-N-acetylalanine2 def: "Protein RPAB3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P52434] xref: UniProtKB:P52434 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063138 ! RPAB3_HUMAN [Term] id: CCO:B0070152 name: RPAP3_HUMAN-Phosphoserine87 def: "Protein RPAP3_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q9H6T3] xref: UniProtKB:Q9H6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063095 ! RPAP3_HUMAN [Term] id: CCO:B0070153 name: RPAP3_HUMAN-Phosphothreonine111 def: "Protein RPAP3_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:Q9H6T3] xref: UniProtKB:Q9H6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063095 ! RPAP3_HUMAN [Term] id: CCO:B0070154 name: RPAP3_HUMAN-Phosphoserine116 def: "Protein RPAP3_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q9H6T3] xref: UniProtKB:Q9H6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063095 ! RPAP3_HUMAN [Term] id: CCO:B0070155 name: RPAP3_HUMAN-Phosphoserine119 def: "Protein RPAP3_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q9H6T3] xref: UniProtKB:Q9H6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063095 ! RPAP3_HUMAN [Term] id: CCO:B0070156 name: RPAP3_HUMAN-Phosphoserine121 def: "Protein RPAP3_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q9H6T3] xref: UniProtKB:Q9H6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063095 ! RPAP3_HUMAN [Term] id: CCO:B0070157 name: RPAP3_HUMAN-Phosphoserine481 def: "Protein RPAP3_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:Q9H6T3] xref: UniProtKB:Q9H6T3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063095 ! RPAP3_HUMAN [Term] id: CCO:B0070158 name: RPB9_HUMAN-Phosphoserine73 def: "Protein RPB9_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:P36954] xref: UniProtKB:P36954 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0055314 ! RPB9_HUMAN [Term] id: CCO:B0070159 name: RPC3_HUMAN-Phosphoserine194 def: "Protein RPC3_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q9BUI4] xref: UniProtKB:Q9BUI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000408 ! DNA-directed RNA polymerase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000271 ! DNA-directed RNA polymerase III complex relationship: transformation_of CCO:B0058521 ! RPC3_HUMAN [Term] id: CCO:B0070160 name: RPC7_HUMAN-Phosphoserine157 def: "Protein RPC7_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:O15318] xref: UniProtKB:O15318 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054428 ! RPC7_HUMAN [Term] id: CCO:B0070161 name: RPE65_HUMAN-N-acetylserine2 def: "Protein RPE65_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q16518] comment: By similarity xref: UniProtKB:Q16518 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056140 ! RPE65_HUMAN [Term] id: CCO:B0070162 name: RPGF2_HUMAN-Phosphoserine418 def: "Protein RPGF2_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:Q9Y4G8] comment: By similarity xref: UniProtKB:Q9Y4G8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:B0070163 name: RPGF2_HUMAN-Phosphoserine420 def: "Protein RPGF2_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:Q9Y4G8] comment: By similarity xref: UniProtKB:Q9Y4G8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:B0070164 name: RPGF2_HUMAN-Phosphoserine935 def: "Protein RPGF2_HUMAN with the residue 935 substituted with Phosphoserine" [UniProtKB:Q9Y4G8] xref: UniProtKB:Q9Y4G8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:B0070165 name: RPGF2_HUMAN-Phosphoserine1022 def: "Protein RPGF2_HUMAN with the residue 1022 substituted with Phosphoserine" [UniProtKB:Q9Y4G8] xref: UniProtKB:Q9Y4G8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:B0070166 name: RPGF2_HUMAN-Phosphoserine1116 def: "Protein RPGF2_HUMAN with the residue 1116 substituted with Phosphoserine" [UniProtKB:Q9Y4G8] xref: UniProtKB:Q9Y4G8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:B0070167 name: RPGF2_HUMAN-Phosphothreonine1119 def: "Protein RPGF2_HUMAN with the residue 1119 substituted with Phosphothreonine" [UniProtKB:Q9Y4G8] xref: UniProtKB:Q9Y4G8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:B0070168 name: RPGF4_HUMAN-Phosphotyrosine681 def: "Protein RPGF4_HUMAN with the residue 681 substituted with Phosphotyrosine" [UniProtKB:Q8WZA2] comment: By similarity xref: UniProtKB:Q8WZA2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058055 ! RPGF4_HUMAN [Term] id: CCO:B0070169 name: RPGF6_HUMAN-Phosphothreonine496 def: "Protein RPGF6_HUMAN with the residue 496 substituted with Phosphothreonine" [UniProtKB:Q8TEU7] xref: UniProtKB:Q8TEU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057956 ! RPGF6_HUMAN [Term] id: CCO:B0070170 name: RPGF6_HUMAN-Phosphoserine1070 def: "Protein RPGF6_HUMAN with the residue 1070 substituted with Phosphoserine" [UniProtKB:Q8TEU7] xref: UniProtKB:Q8TEU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057956 ! RPGF6_HUMAN [Term] id: CCO:B0070171 name: RPGF6_HUMAN-Phosphoserine1494 def: "Protein RPGF6_HUMAN with the residue 1494 substituted with Phosphoserine" [UniProtKB:Q8TEU7] xref: UniProtKB:Q8TEU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057956 ! RPGF6_HUMAN [Term] id: CCO:B0070172 name: RPGF6_HUMAN-Phosphothreonine1507 def: "Protein RPGF6_HUMAN with the residue 1507 substituted with Phosphothreonine" [UniProtKB:Q8TEU7] xref: UniProtKB:Q8TEU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003512 ! Ras GTPase binding relationship: has_function CCO:F0004538 ! GTP-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057956 ! RPGF6_HUMAN [Term] id: CCO:B0070173 name: RPGP2_HUMAN-Phosphoserine7 def: "Protein RPGP2_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q684P5] comment: by PKG/PRKG1; in vitro; xref: UniProtKB:Q684P5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056697 ! RPGP2_HUMAN [Term] id: CCO:B0070174 name: RPGP2_HUMAN-Phosphoserine45 def: "Protein RPGP2_HUMAN with the residue 45 substituted with Phosphoserine" [UniProtKB:Q684P5] xref: UniProtKB:Q684P5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056697 ! RPGP2_HUMAN [Term] id: CCO:B0070175 name: RPGP2_HUMAN-Phosphothreonine49 def: "Protein RPGP2_HUMAN with the residue 49 substituted with Phosphothreonine" [UniProtKB:Q684P5] xref: UniProtKB:Q684P5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056697 ! RPGP2_HUMAN [Term] id: CCO:B0070176 name: RPGP2_HUMAN-Phosphoserine544 def: "Protein RPGP2_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:Q684P5] xref: UniProtKB:Q684P5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056697 ! RPGP2_HUMAN [Term] id: CCO:B0070177 name: RPGP2_HUMAN-Phosphoserine613 def: "Protein RPGP2_HUMAN with the residue 613 substituted with Phosphoserine" [UniProtKB:Q684P5] comment: By similarity xref: UniProtKB:Q684P5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056697 ! RPGP2_HUMAN [Term] id: CCO:B0070178 name: RRBP1_HUMAN-Phosphoserine1276 def: "Protein RRBP1_HUMAN with the residue 1276 substituted with Phosphoserine" [UniProtKB:Q9P2E9] xref: UniProtKB:Q9P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037300 ! RRBP1_HUMAN [Term] id: CCO:B0070179 name: RRBP1_HUMAN-Phosphoserine1277 def: "Protein RRBP1_HUMAN with the residue 1277 substituted with Phosphoserine" [UniProtKB:Q9P2E9] xref: UniProtKB:Q9P2E9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037300 ! RRBP1_HUMAN [Term] id: CCO:B0070180 name: RREB1_HUMAN-Phosphoserine36 def: "Protein RREB1_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070181 name: RREB1_HUMAN-Phosphoserine42 def: "Protein RREB1_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070182 name: RREB1_HUMAN-Phosphoserine231 def: "Protein RREB1_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070183 name: RREB1_HUMAN-Phosphoserine1134 def: "Protein RREB1_HUMAN with the residue 1134 substituted with Phosphoserine" [UniProtKB:Q92766] comment: By similarity xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070184 name: RREB1_HUMAN-Phosphoserine1135 def: "Protein RREB1_HUMAN with the residue 1135 substituted with Phosphoserine" [UniProtKB:Q92766] comment: By similarity xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070185 name: RREB1_HUMAN-Phosphoserine1167 def: "Protein RREB1_HUMAN with the residue 1167 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070186 name: RREB1_HUMAN-Phosphoserine1174 def: "Protein RREB1_HUMAN with the residue 1174 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070187 name: RREB1_HUMAN-Phosphoserine1175 def: "Protein RREB1_HUMAN with the residue 1175 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070188 name: RREB1_HUMAN-Phosphoserine1219 def: "Protein RREB1_HUMAN with the residue 1219 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070189 name: RREB1_HUMAN-Phosphoserine1225 def: "Protein RREB1_HUMAN with the residue 1225 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070190 name: RREB1_HUMAN-Phosphothreonine1315 def: "Protein RREB1_HUMAN with the residue 1315 substituted with Phosphothreonine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000817 ! nuclear body relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070191 name: RREB1_HUMAN-Phosphoserine1388 def: "Protein RREB1_HUMAN with the residue 1388 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070192 name: RREB1_HUMAN-Phosphoserine1653 def: "Protein RREB1_HUMAN with the residue 1653 substituted with Phosphoserine" [UniProtKB:Q92766] xref: UniProtKB:Q92766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058091 ! RREB1_HUMAN [Term] id: CCO:B0070193 name: RRN3_HUMAN-Phosphoserine44 def: "Protein RRN3_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q9NYV6] xref: UniProtKB:Q9NYV6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0058974 ! RRN3_HUMAN [Term] id: CCO:B0070194 name: RRN3_HUMAN-Phosphoserine170 def: "Protein RRN3_HUMAN with the residue 170 substituted with Phosphoserine" [UniProtKB:Q9NYV6] xref: UniProtKB:Q9NYV6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058974 ! RRN3_HUMAN [Term] id: CCO:B0070195 name: RRN3_HUMAN-Phosphoserine172 def: "Protein RRN3_HUMAN with the residue 172 substituted with Phosphoserine" [UniProtKB:Q9NYV6] xref: UniProtKB:Q9NYV6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058974 ! RRN3_HUMAN [Term] id: CCO:B0070196 name: RRN3_HUMAN-Phosphoserine640 def: "Protein RRN3_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q9NYV6] xref: UniProtKB:Q9NYV6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058974 ! RRN3_HUMAN [Term] id: CCO:B0070197 name: RRP5_HUMAN-Phosphoserine1360 def: "Protein RRP5_HUMAN with the residue 1360 substituted with Phosphoserine" [UniProtKB:Q14690] xref: UniProtKB:Q14690 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0062995 ! RRP5_HUMAN [Term] id: CCO:B0070198 name: RRP5_HUMAN-Phosphoserine1493 def: "Protein RRP5_HUMAN with the residue 1493 substituted with Phosphoserine" [UniProtKB:Q14690] xref: UniProtKB:Q14690 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062995 ! RRP5_HUMAN [Term] id: CCO:B0070199 name: RRP5_HUMAN-Phosphoserine1498 def: "Protein RRP5_HUMAN with the residue 1498 substituted with Phosphoserine" [UniProtKB:Q14690] xref: UniProtKB:Q14690 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062995 ! RRP5_HUMAN [Term] id: CCO:B0070200 name: RS11_HUMAN-N-acetylalanine2 def: "Protein RS11_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P62280] xref: UniProtKB:P62280 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004192 ! rRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002087 ! cytosolic large ribosomal subunit relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0063085 ! RS11_HUMAN [Term] id: CCO:B0070201 name: RS26_HUMAN-Phosphothreonine96 def: "Protein RS26_HUMAN with the residue 96 substituted with Phosphothreonine" [UniProtKB:P62854] xref: UniProtKB:P62854 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063353 ! RS26_HUMAN [Term] id: CCO:B0070202 name: RS28_HUMAN-N-acetylmethionine1 def: "Protein RS28_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P62857] comment: By similarity xref: UniProtKB:P62857 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063368 ! RS28_HUMAN [Term] id: CCO:B0070203 name: RS2_HUMAN-Phosphoserine77 def: "Protein RS2_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:P15880] comment: By similarity xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070204 name: RS2_HUMAN-Phosphotyrosine82 def: "Protein RS2_HUMAN with the residue 82 substituted with Phosphotyrosine" [UniProtKB:P15880] comment: By similarity xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070205 name: RS2_HUMAN-Phosphoserine85 def: "Protein RS2_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:P15880] comment: By similarity xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070206 name: RS2_HUMAN-Phosphotyrosine133 def: "Protein RS2_HUMAN with the residue 133 substituted with Phosphotyrosine" [UniProtKB:P15880] comment: By similarity xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070207 name: RS2_HUMAN-Phosphoserine264 def: "Protein RS2_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:P15880] xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070208 name: RS2_HUMAN-Phosphothreonine278 def: "Protein RS2_HUMAN with the residue 278 substituted with Phosphothreonine" [UniProtKB:P15880] xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070209 name: RS2_HUMAN-Phosphoserine281 def: "Protein RS2_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:P15880] xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070210 name: RS2_HUMAN-Phosphothreonine293 def: "Protein RS2_HUMAN with the residue 293 substituted with Phosphothreonine" [UniProtKB:P15880] xref: UniProtKB:P15880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:B0070211 name: RS3_HUMAN-N-acetylalanine2 def: "Protein RS3_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P23396] xref: UniProtKB:P23396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:B0070212 name: RS3_HUMAN-Phosphothreonine220 def: "Protein RS3_HUMAN with the residue 220 substituted with Phosphothreonine" [UniProtKB:P23396] xref: UniProtKB:P23396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:B0070213 name: RS5_HUMAN-N-acetylthreonine2 def: "Protein RS5_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P46782] xref: UniProtKB:P46782 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063061 ! RS5_HUMAN [Term] id: CCO:B0070214 name: RS6_HUMAN-Phosphoserine78 def: "Protein RS6_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:P62753] xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0000756 ! small ribosomal subunit relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070215 name: RS6_HUMAN-Phosphoserine148 def: "Protein RS6_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:P62753] xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070216 name: RS6_HUMAN-Phosphoserine235 def: "Protein RS6_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:P62753] xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070217 name: RS6_HUMAN-Phosphoserine236 def: "Protein RS6_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:P62753] xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070218 name: RS6_HUMAN-Phosphoserine240 def: "Protein RS6_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:P62753] xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070219 name: RS6_HUMAN-Phosphoserine244 def: "Protein RS6_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:P62753] xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070220 name: RS6_HUMAN-Phosphoserine246 def: "Protein RS6_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:P62753] comment: By similarity xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070221 name: RS6_HUMAN-Phosphoserine247 def: "Protein RS6_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:P62753] xref: UniProtKB:P62753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:B0070222 name: RS8_HUMAN-Phosphothreonine130 def: "Protein RS8_HUMAN with the residue 130 substituted with Phosphothreonine" [UniProtKB:P62241] xref: UniProtKB:P62241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0002089 ! cytosolic small ribosomal subunit relationship: transformation_of CCO:B0005734 ! RS8_HUMAN [Term] id: CCO:B0070223 name: RSF1_HUMAN-Phosphoserine382 def: "Protein RSF1_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070224 name: RSF1_HUMAN-Phosphoserine387 def: "Protein RSF1_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070225 name: RSF1_HUMAN-Phosphothreonine496 def: "Protein RSF1_HUMAN with the residue 496 substituted with Phosphothreonine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070226 name: RSF1_HUMAN-Phosphoserine514 def: "Protein RSF1_HUMAN with the residue 514 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070227 name: RSF1_HUMAN-Phosphoserine594 def: "Protein RSF1_HUMAN with the residue 594 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070228 name: RSF1_HUMAN-Phosphoserine612 def: "Protein RSF1_HUMAN with the residue 612 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070229 name: RSF1_HUMAN-Phosphoserine619 def: "Protein RSF1_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070230 name: RSF1_HUMAN-Phosphoserine738 def: "Protein RSF1_HUMAN with the residue 738 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070231 name: RSF1_HUMAN-Phosphoserine768 def: "Protein RSF1_HUMAN with the residue 768 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070232 name: RSF1_HUMAN-Phosphoserine772 def: "Protein RSF1_HUMAN with the residue 772 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070233 name: RSF1_HUMAN-Phosphoserine1086 def: "Protein RSF1_HUMAN with the residue 1086 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070234 name: RSF1_HUMAN-Phosphoserine1088 def: "Protein RSF1_HUMAN with the residue 1088 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070235 name: RSF1_HUMAN-Phosphoserine1095 def: "Protein RSF1_HUMAN with the residue 1095 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070236 name: RSF1_HUMAN-Phosphoserine1211 def: "Protein RSF1_HUMAN with the residue 1211 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070237 name: RSF1_HUMAN-Phosphoserine1213 def: "Protein RSF1_HUMAN with the residue 1213 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070238 name: RSF1_HUMAN-Phosphoserine1216 def: "Protein RSF1_HUMAN with the residue 1216 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070239 name: RSF1_HUMAN-Phosphoserine1267 def: "Protein RSF1_HUMAN with the residue 1267 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070240 name: RSF1_HUMAN-Phosphothreonine1268 def: "Protein RSF1_HUMAN with the residue 1268 substituted with Phosphothreonine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070241 name: RSF1_HUMAN-Phosphotyrosine1271 def: "Protein RSF1_HUMAN with the residue 1271 substituted with Phosphotyrosine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070242 name: RSF1_HUMAN-Phosphothreonine1295 def: "Protein RSF1_HUMAN with the residue 1295 substituted with Phosphothreonine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070243 name: RSF1_HUMAN-Phosphoserine1315 def: "Protein RSF1_HUMAN with the residue 1315 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070244 name: RSF1_HUMAN-Phosphoserine1335 def: "Protein RSF1_HUMAN with the residue 1335 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070245 name: RSF1_HUMAN-Phosphoserine1349 def: "Protein RSF1_HUMAN with the residue 1349 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0005669 ! histone binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001147 ! RSF complex relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070246 name: RSF1_HUMAN-Phosphoserine1354 def: "Protein RSF1_HUMAN with the residue 1354 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070247 name: RSF1_HUMAN-Phosphoserine1365 def: "Protein RSF1_HUMAN with the residue 1365 substituted with Phosphoserine" [UniProtKB:Q96T23] xref: UniProtKB:Q96T23 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:B0070248 name: RSLAA_HUMAN-Cysteine methyl ester200 def: "Protein RSLAA_HUMAN with the residue 200 substituted with Cysteine methyl ester" [UniProtKB:Q92737] comment: By similarity xref: UniProtKB:Q92737 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058085 ! RSLAA_HUMAN [Term] id: CCO:B0070249 name: RSLAB_HUMAN-Cysteine methyl ester200 def: "Protein RSLAB_HUMAN with the residue 200 substituted with Cysteine methyl ester" [UniProtKB:Q96S79] comment: By similarity xref: UniProtKB:Q96S79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058388 ! RSLAB_HUMAN [Term] id: CCO:B0070250 name: RSPO4_HUMAN-Phosphotyrosine112 def: "Protein RSPO4_HUMAN with the residue 112 substituted with Phosphotyrosine" [UniProtKB:Q2I0M5] xref: UniProtKB:Q2I0M5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031672 ! RSPO4_HUMAN [Term] id: CCO:B0070251 name: RT09_HUMAN-Phosphotyrosine262 def: "Protein RT09_HUMAN with the residue 262 substituted with Phosphotyrosine" [UniProtKB:P82933] xref: UniProtKB:P82933 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000315 ! structural constituent of ribosome relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000346 ! mitochondrial small ribosomal subunit relationship: located_in CCO:C0000407 ! ribosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0043448 ! RT09_HUMAN [Term] id: CCO:B0070252 name: RT29_HUMAN-Phosphothreonine93 def: "Protein RT29_HUMAN with the residue 93 substituted with Phosphothreonine" [UniProtKB:P51398] xref: UniProtKB:P51398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055464 ! RT29_HUMAN [Term] id: CCO:B0070253 name: RT29_HUMAN-Phosphothreonine272 def: "Protein RT29_HUMAN with the residue 272 substituted with Phosphothreonine" [UniProtKB:P51398] xref: UniProtKB:P51398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055464 ! RT29_HUMAN [Term] id: CCO:B0070254 name: RTKN_HUMAN-Phosphoserine232 def: "Protein RTKN_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q9BST9] xref: UniProtKB:Q9BST9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058510 ! RTKN_HUMAN [Term] id: CCO:B0070255 name: RTKN_HUMAN-Phosphoserine241 def: "Protein RTKN_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:Q9BST9] xref: UniProtKB:Q9BST9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058510 ! RTKN_HUMAN [Term] id: CCO:B0070256 name: RTKN_HUMAN-Phosphoserine543 def: "Protein RTKN_HUMAN with the residue 543 substituted with Phosphoserine" [UniProtKB:Q9BST9] xref: UniProtKB:Q9BST9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001400 ! GTPase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0003532 ! GTP-Rho binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058510 ! RTKN_HUMAN [Term] id: CCO:B0070257 name: RTN1_HUMAN-Phosphoserine350 def: "Protein RTN1_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:Q16799] comment: By similarity xref: UniProtKB:Q16799 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056177 ! RTN1_HUMAN [Term] id: CCO:B0070258 name: RTN1_HUMAN-Phosphoserine352 def: "Protein RTN1_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q16799] xref: UniProtKB:Q16799 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056177 ! RTN1_HUMAN [Term] id: CCO:B0070259 name: RTN1_HUMAN-Phosphoserine487 def: "Protein RTN1_HUMAN with the residue 487 substituted with Phosphoserine" [UniProtKB:Q16799] xref: UniProtKB:Q16799 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: transformation_of CCO:B0056177 ! RTN1_HUMAN [Term] id: CCO:B0070260 name: RTN2_HUMAN-Phosphoserine44 def: "Protein RTN2_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:O75298] comment: By similarity xref: UniProtKB:O75298 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: transformation_of CCO:B0054615 ! RTN2_HUMAN [Term] id: CCO:B0070261 name: RTN4_HUMAN-Phosphoserine181 def: "Protein RTN4_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q9NQC3] xref: UniProtKB:Q9NQC3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:B0070262 name: RU17_HUMAN-Phosphotyrosine126 def: "Protein RU17_HUMAN with the residue 126 substituted with Phosphotyrosine" [UniProtKB:P08621] xref: UniProtKB:P08621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:B0070263 name: RU17_HUMAN-Phosphoserine226 def: "Protein RU17_HUMAN with the residue 226 substituted with Phosphoserine" [UniProtKB:P08621] xref: UniProtKB:P08621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:B0070264 name: RU17_HUMAN-Phosphoserine266 def: "Protein RU17_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:P08621] xref: UniProtKB:P08621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:B0070265 name: RU17_HUMAN-Phosphoserine268 def: "Protein RU17_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:P08621] xref: UniProtKB:P08621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:B0070266 name: RU17_HUMAN-Phosphoserine320 def: "Protein RU17_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:P08621] xref: UniProtKB:P08621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:B0070267 name: RU17_HUMAN-Phosphoserine410 def: "Protein RU17_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:P08621] xref: UniProtKB:P08621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:B0070268 name: RU2A_HUMAN-Phosphoserine197 def: "Protein RU2A_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:P09661] xref: UniProtKB:P09661 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000288 ! snRNP U2 relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0063189 ! RU2A_HUMAN [Term] id: CCO:B0070269 name: RYBP_HUMAN-Phosphoserine127 def: "Protein RYBP_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q8N488] xref: UniProtKB:Q8N488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057465 ! RYBP_HUMAN [Term] id: CCO:B0070270 name: RYBP_HUMAN-Phosphoserine130 def: "Protein RYBP_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q8N488] xref: UniProtKB:Q8N488 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057465 ! RYBP_HUMAN [Term] id: CCO:B0070271 name: RYK_HUMAN-Phosphotyrosine492 def: "Protein RYK_HUMAN with the residue 492 substituted with Phosphotyrosine" [UniProtKB:P34925] comment: by autocatalysis; By similarity xref: UniProtKB:P34925 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018655 ! RYK_HUMAN [Term] id: CCO:B0070272 name: RYR2_HUMAN-Phosphoserine2806 def: "Protein RYR2_HUMAN with the residue 2806 substituted with Phosphoserine" [UniProtKB:Q92736] comment: by CaMK; By similarity xref: UniProtKB:Q92736 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001495 ! ryanodine-sensitive calcium-release channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0002735 ! calcium-release channel activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0049439 ! RYR2_HUMAN [Term] id: CCO:B0070273 name: S10AA_HUMAN-Phosphotyrosine25 def: "Protein S10AA_HUMAN with the residue 25 substituted with Phosphotyrosine" [UniProtKB:P60903] xref: UniProtKB:P60903 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055600 ! S10AA_HUMAN [Term] id: CCO:B0070274 name: S10AB_HUMAN-Phosphothreonine10 def: "Protein S10AB_HUMAN with the residue 10 substituted with Phosphothreonine" [UniProtKB:P31949] xref: UniProtKB:P31949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0007315 ! S100 beta binding relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:B0070275 name: S10AB_HUMAN-Phosphotyrosine30 def: "Protein S10AB_HUMAN with the residue 30 substituted with Phosphotyrosine" [UniProtKB:P31949] xref: UniProtKB:P31949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:B0070276 name: S10AB_HUMAN-Phosphotyrosine32 def: "Protein S10AB_HUMAN with the residue 32 substituted with Phosphotyrosine" [UniProtKB:P31949] xref: UniProtKB:P31949 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:B0070277 name: S20A1_HUMAN-Phosphoserine265 def: "Protein S20A1_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q8WUM9] xref: UniProtKB:Q8WUM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001554 ! inorganic phosphate transmembrane transporter activity relationship: has_function CCO:F0001613 ! sodium:phosphate symporter activity relationship: has_function CCO:F0002742 ! symporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057982 ! S20A1_HUMAN [Term] id: CCO:B0070278 name: S20A1_HUMAN-Phosphoserine269 def: "Protein S20A1_HUMAN with the residue 269 substituted with Phosphoserine" [UniProtKB:Q8WUM9] xref: UniProtKB:Q8WUM9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057982 ! S20A1_HUMAN [Term] id: CCO:B0070279 name: S30BP_HUMAN-Phosphoserine18 def: "Protein S30BP_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q9UHR5] xref: UniProtKB:Q9UHR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059148 ! S30BP_HUMAN [Term] id: CCO:B0070280 name: S30BP_HUMAN-Phosphoserine22 def: "Protein S30BP_HUMAN with the residue 22 substituted with Phosphoserine" [UniProtKB:Q9UHR5] xref: UniProtKB:Q9UHR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059148 ! S30BP_HUMAN [Term] id: CCO:B0070281 name: S30BP_HUMAN-Phosphoserine43 def: "Protein S30BP_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q9UHR5] xref: UniProtKB:Q9UHR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059148 ! S30BP_HUMAN [Term] id: CCO:B0070282 name: S30BP_HUMAN-Phosphoserine113 def: "Protein S30BP_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q9UHR5] xref: UniProtKB:Q9UHR5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059148 ! S30BP_HUMAN [Term] id: CCO:B0070283 name: S35B2_HUMAN-Phosphoserine427 def: "Protein S35B2_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q8TB61] xref: UniProtKB:Q8TB61 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0006285 ! 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057898 ! S35B2_HUMAN [Term] id: CCO:B0070284 name: S35E1_HUMAN-Phosphothreonine352 def: "Protein S35E1_HUMAN with the residue 352 substituted with Phosphothreonine" [UniProtKB:Q96K37] comment: By similarity xref: UniProtKB:Q96K37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063513 ! S35E1_HUMAN [Term] id: CCO:B0070285 name: S35E1_HUMAN-Phosphoserine363 def: "Protein S35E1_HUMAN with the residue 363 substituted with Phosphoserine" [UniProtKB:Q96K37] xref: UniProtKB:Q96K37 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063513 ! S35E1_HUMAN [Term] id: CCO:B0070286 name: S38A3_HUMAN-Phosphoserine52 def: "Protein S38A3_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q99624] comment: By similarity xref: UniProtKB:Q99624 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063485 ! S38A3_HUMAN [Term] id: CCO:B0070287 name: S38A3_HUMAN-Phosphoserine54 def: "Protein S38A3_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q99624] comment: By similarity xref: UniProtKB:Q99624 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001538 ! L-histidine transmembrane transporter activity relationship: has_function CCO:F0002654 ! L-alanine transmembrane transporter activity relationship: has_function CCO:F0002656 ! L-asparagine transmembrane transporter activity relationship: has_function CCO:F0002660 ! L-glutamine transmembrane transporter activity relationship: has_function CCO:F0002742 ! symporter activity relationship: has_function CCO:F0002746 ! antiporter activity relationship: has_function CCO:F0004656 ! sodium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063485 ! S38A3_HUMAN [Term] id: CCO:B0070288 name: SAA_HUMAN-N4,N4-dimethylasparagine101 def: "Protein SAA_HUMAN with the residue 101 substituted with N4,N4-dimethylasparagine" [UniProtKB:P02735] comment: Probable xref: UniProtKB:P02735 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000196 ! G-protein-coupled receptor binding relationship: has_function CCO:F0001556 ! lipid transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0054869 ! SAA_HUMAN [Term] id: CCO:B0070289 name: SACS_HUMAN-Phosphotyrosine4333 def: "Protein SACS_HUMAN with the residue 4333 substituted with Phosphotyrosine" [UniProtKB:Q9NZJ4] xref: UniProtKB:Q9NZJ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005994 ! SACS_HUMAN [Term] id: CCO:B0070290 name: SAE2_HUMAN-Phosphoserine592 def: "Protein SAE2_HUMAN with the residue 592 substituted with Phosphoserine" [UniProtKB:Q9UBT2] xref: UniProtKB:Q9UBT2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001691 ! enzyme activator activity relationship: has_function CCO:F0002013 ! small protein activating enzyme activity relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063247 ! SAE2_HUMAN [Term] id: CCO:B0070291 name: SAFB1_HUMAN-Phosphoserine55 def: "Protein SAFB1_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070292 name: SAFB1_HUMAN-Phosphoserine288 def: "Protein SAFB1_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070293 name: SAFB1_HUMAN-Phosphoserine344 def: "Protein SAFB1_HUMAN with the residue 344 substituted with Phosphoserine" [UniProtKB:Q15424] comment: By similarity xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070294 name: SAFB1_HUMAN-Phosphoserine373 def: "Protein SAFB1_HUMAN with the residue 373 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070295 name: SAFB1_HUMAN-Phosphoserine383 def: "Protein SAFB1_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070296 name: SAFB1_HUMAN-Phosphoserine384 def: "Protein SAFB1_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070297 name: SAFB1_HUMAN-Phosphoserine555 def: "Protein SAFB1_HUMAN with the residue 555 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070298 name: SAFB1_HUMAN-Phosphoserine557 def: "Protein SAFB1_HUMAN with the residue 557 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070299 name: SAFB1_HUMAN-Phosphoserine589 def: "Protein SAFB1_HUMAN with the residue 589 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070300 name: SAFB1_HUMAN-Phosphoserine601 def: "Protein SAFB1_HUMAN with the residue 601 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070301 name: SAFB1_HUMAN-Phosphoserine604 def: "Protein SAFB1_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070302 name: SAFB1_HUMAN-Phosphoserine808 def: "Protein SAFB1_HUMAN with the residue 808 substituted with Phosphoserine" [UniProtKB:Q15424] xref: UniProtKB:Q15424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:B0070303 name: SAFB2_HUMAN-Phosphoserine31 def: "Protein SAFB2_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q14151] xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070304 name: SAFB2_HUMAN-Phosphoserine109 def: "Protein SAFB2_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:Q14151] xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070305 name: SAFB2_HUMAN-Phosphoserine207 def: "Protein SAFB2_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:Q14151] xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070306 name: SAFB2_HUMAN-Phosphoserine234 def: "Protein SAFB2_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q14151] comment: By similarity xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070307 name: SAFB2_HUMAN-Phosphoserine287 def: "Protein SAFB2_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q14151] xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070308 name: SAFB2_HUMAN-Phosphoserine331 def: "Protein SAFB2_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q14151] comment: By similarity xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070309 name: SAFB2_HUMAN-Phosphoserine343 def: "Protein SAFB2_HUMAN with the residue 343 substituted with Phosphoserine" [UniProtKB:Q14151] xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070310 name: SAFB2_HUMAN-Phosphoserine513 def: "Protein SAFB2_HUMAN with the residue 513 substituted with Phosphoserine" [UniProtKB:Q14151] xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070311 name: SAFB2_HUMAN-Phosphoserine613 def: "Protein SAFB2_HUMAN with the residue 613 substituted with Phosphoserine" [UniProtKB:Q14151] xref: UniProtKB:Q14151 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:B0070312 name: SALL1_HUMAN-Phosphoserine586 def: "Protein SALL1_HUMAN with the residue 586 substituted with Phosphoserine" [UniProtKB:Q9NSC2] comment: By similarity xref: UniProtKB:Q9NSC2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058914 ! SALL1_HUMAN [Term] id: CCO:B0070313 name: SALL2_HUMAN-Phosphoserine609 def: "Protein SALL2_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:Q9Y467] xref: UniProtKB:Q9Y467 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059351 ! SALL2_HUMAN [Term] id: CCO:B0070314 name: SALL2_HUMAN-Phosphothreonine616 def: "Protein SALL2_HUMAN with the residue 616 substituted with Phosphothreonine" [UniProtKB:Q9Y467] xref: UniProtKB:Q9Y467 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059351 ! SALL2_HUMAN [Term] id: CCO:B0070315 name: SALL2_HUMAN-Phosphoserine623 def: "Protein SALL2_HUMAN with the residue 623 substituted with Phosphoserine" [UniProtKB:Q9Y467] xref: UniProtKB:Q9Y467 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059351 ! SALL2_HUMAN [Term] id: CCO:B0070316 name: SAP30_HUMAN-Phosphoserine131 def: "Protein SAP30_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:O75446] xref: UniProtKB:O75446 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054637 ! SAP30_HUMAN [Term] id: CCO:B0070317 name: SAP30_HUMAN-Phosphoserine138 def: "Protein SAP30_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:O75446] xref: UniProtKB:O75446 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000008 ! histone deacetylase complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054637 ! SAP30_HUMAN [Term] id: CCO:B0070318 name: SAR1A_HUMAN-Phosphothreonine139 def: "Protein SAR1A_HUMAN with the residue 139 substituted with Phosphothreonine" [UniProtKB:Q9NR31] xref: UniProtKB:Q9NR31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058885 ! SAR1A_HUMAN [Term] id: CCO:B0070319 name: SAS10_HUMAN-Phosphothreonine362 def: "Protein SAS10_HUMAN with the residue 362 substituted with Phosphothreonine" [UniProtKB:Q9NQZ2] xref: UniProtKB:Q9NQZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006160 ! SAS10_HUMAN [Term] id: CCO:B0070320 name: SAS6_HUMAN-Phosphoserine510 def: "Protein SAS6_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q6UVJ0] xref: UniProtKB:Q6UVJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001918 ! SAS6_HUMAN [Term] id: CCO:B0070321 name: SAS6_HUMAN-Phosphoserine657 def: "Protein SAS6_HUMAN with the residue 657 substituted with Phosphoserine" [UniProtKB:Q6UVJ0] xref: UniProtKB:Q6UVJ0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001918 ! SAS6_HUMAN [Term] id: CCO:B0070322 name: SATB2_HUMAN-Phosphoserine39 def: "Protein SATB2_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q9UPW6] xref: UniProtKB:Q9UPW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059270 ! SATB2_HUMAN [Term] id: CCO:B0070323 name: SATB2_HUMAN-Phosphoserine446 def: "Protein SATB2_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:Q9UPW6] xref: UniProtKB:Q9UPW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059270 ! SATB2_HUMAN [Term] id: CCO:B0070324 name: SATB2_HUMAN-Phosphoserine449 def: "Protein SATB2_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:Q9UPW6] xref: UniProtKB:Q9UPW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059270 ! SATB2_HUMAN [Term] id: CCO:B0070325 name: SATB2_HUMAN-Phosphoserine450 def: "Protein SATB2_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q9UPW6] xref: UniProtKB:Q9UPW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059270 ! SATB2_HUMAN [Term] id: CCO:B0070326 name: SATB2_HUMAN-Phosphoserine452 def: "Protein SATB2_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:Q9UPW6] xref: UniProtKB:Q9UPW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059270 ! SATB2_HUMAN [Term] id: CCO:B0070327 name: SC16A_HUMAN-Phosphoserine136 def: "Protein SC16A_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070328 name: SC16A_HUMAN-Phosphothreonine415 def: "Protein SC16A_HUMAN with the residue 415 substituted with Phosphothreonine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070329 name: SC16A_HUMAN-Phosphoserine417 def: "Protein SC16A_HUMAN with the residue 417 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070330 name: SC16A_HUMAN-Phosphoserine1149 def: "Protein SC16A_HUMAN with the residue 1149 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070331 name: SC16A_HUMAN-Phosphoserine1169 def: "Protein SC16A_HUMAN with the residue 1169 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070332 name: SC16A_HUMAN-Phosphoserine1190 def: "Protein SC16A_HUMAN with the residue 1190 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070333 name: SC16A_HUMAN-Phosphoserine1191 def: "Protein SC16A_HUMAN with the residue 1191 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070334 name: SC16A_HUMAN-Phosphoserine1786 def: "Protein SC16A_HUMAN with the residue 1786 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070335 name: SC16A_HUMAN-Phosphoserine1844 def: "Protein SC16A_HUMAN with the residue 1844 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070336 name: SC16A_HUMAN-Phosphothreonine1876 def: "Protein SC16A_HUMAN with the residue 1876 substituted with Phosphothreonine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070337 name: SC16A_HUMAN-Phosphoserine1903 def: "Protein SC16A_HUMAN with the residue 1903 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070338 name: SC16A_HUMAN-Phosphoserine1905 def: "Protein SC16A_HUMAN with the residue 1905 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070339 name: SC16A_HUMAN-Phosphoserine2107 def: "Protein SC16A_HUMAN with the residue 2107 substituted with Phosphoserine" [UniProtKB:O15027] xref: UniProtKB:O15027 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:B0070340 name: SC23A_HUMAN-Phosphothreonine308 def: "Protein SC23A_HUMAN with the residue 308 substituted with Phosphothreonine" [UniProtKB:Q15436] xref: UniProtKB:Q15436 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005583 ! SC23A_HUMAN [Term] id: CCO:B0070341 name: SCAP_HUMAN-Phosphotyrosine243 def: "Protein SCAP_HUMAN with the residue 243 substituted with Phosphotyrosine" [UniProtKB:Q12770] xref: UniProtKB:Q12770 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0055838 ! SCAP_HUMAN [Term] id: CCO:B0070342 name: SCAP_HUMAN-Phosphoserine851 def: "Protein SCAP_HUMAN with the residue 851 substituted with Phosphoserine" [UniProtKB:Q12770] xref: UniProtKB:Q12770 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055838 ! SCAP_HUMAN [Term] id: CCO:B0070343 name: SCAP_HUMAN-Phosphoserine907 def: "Protein SCAP_HUMAN with the residue 907 substituted with Phosphoserine" [UniProtKB:Q12770] xref: UniProtKB:Q12770 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055838 ! SCAP_HUMAN [Term] id: CCO:B0070344 name: SCFD1_HUMAN-Phosphoserine303 def: "Protein SCFD1_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:Q8WVM8] xref: UniProtKB:Q8WVM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006349 ! SCFD1_HUMAN [Term] id: CCO:B0070345 name: SCG2_HUMAN-Sulfotyrosine151 def: "Protein SCG2_HUMAN with the residue 151 substituted with Sulfotyrosine" [UniProtKB:P13521] xref: UniProtKB:P13521 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055014 ! SCG2_HUMAN [Term] id: CCO:B0070346 name: SCG2_HUMAN-Phosphoserine532 def: "Protein SCG2_HUMAN with the residue 532 substituted with Phosphoserine" [UniProtKB:P13521] xref: UniProtKB:P13521 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0005617 ! chemoattractant activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: transformation_of CCO:B0055014 ! SCG2_HUMAN [Term] id: CCO:B0070347 name: SCG2_HUMAN-Phosphoserine533 def: "Protein SCG2_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:P13521] xref: UniProtKB:P13521 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055014 ! SCG2_HUMAN [Term] id: CCO:B0070348 name: SCMH1_HUMAN-Phosphoserine649 def: "Protein SCMH1_HUMAN with the residue 649 substituted with Phosphoserine" [UniProtKB:Q96GD3] xref: UniProtKB:Q96GD3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:B0070349 name: SCML1_HUMAN-Phosphoserine17 def: "Protein SCML1_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q9UN30] xref: UniProtKB:Q9UN30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059246 ! SCML1_HUMAN [Term] id: CCO:B0070350 name: SCML2_HUMAN-Phosphoserine256 def: "Protein SCML2_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070351 name: SCML2_HUMAN-Phosphoserine258 def: "Protein SCML2_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070352 name: SCML2_HUMAN-Phosphoserine267 def: "Protein SCML2_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070353 name: SCML2_HUMAN-Phosphoserine299 def: "Protein SCML2_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070354 name: SCML2_HUMAN-Phosphoserine300 def: "Protein SCML2_HUMAN with the residue 300 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070355 name: SCML2_HUMAN-Phosphothreonine305 def: "Protein SCML2_HUMAN with the residue 305 substituted with Phosphothreonine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070356 name: SCML2_HUMAN-Phosphoserine499 def: "Protein SCML2_HUMAN with the residue 499 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070357 name: SCML2_HUMAN-Phosphothreonine503 def: "Protein SCML2_HUMAN with the residue 503 substituted with Phosphothreonine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070358 name: SCML2_HUMAN-Phosphoserine511 def: "Protein SCML2_HUMAN with the residue 511 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070359 name: SCML2_HUMAN-Phosphoserine570 def: "Protein SCML2_HUMAN with the residue 570 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070360 name: SCML2_HUMAN-Phosphoserine576 def: "Protein SCML2_HUMAN with the residue 576 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070361 name: SCML2_HUMAN-Phosphoserine583 def: "Protein SCML2_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070362 name: SCML2_HUMAN-Phosphoserine590 def: "Protein SCML2_HUMAN with the residue 590 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070363 name: SCML2_HUMAN-Phosphoserine594 def: "Protein SCML2_HUMAN with the residue 594 substituted with Phosphoserine" [UniProtKB:Q9UQR0] xref: UniProtKB:Q9UQR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059284 ! SCML2_HUMAN [Term] id: CCO:B0070364 name: SCNM1_HUMAN-Phosphoserine144 def: "Protein SCNM1_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q9BWG6] xref: UniProtKB:Q9BWG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005251 ! SCNM1_HUMAN [Term] id: CCO:B0070365 name: SCNM1_HUMAN-Phosphoserine219 def: "Protein SCNM1_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q9BWG6] xref: UniProtKB:Q9BWG6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005251 ! SCNM1_HUMAN [Term] id: CCO:B0070366 name: SDCB1_HUMAN-Phosphotyrosine46 def: "Protein SDCB1_HUMAN with the residue 46 substituted with Phosphotyrosine" [UniProtKB:O00560] xref: UniProtKB:O00560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054332 ! SDCB1_HUMAN [Term] id: CCO:B0070367 name: SDCB1_HUMAN-Phosphotyrosine91 def: "Protein SDCB1_HUMAN with the residue 91 substituted with Phosphotyrosine" [UniProtKB:O00560] xref: UniProtKB:O00560 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001439 ! interleukin-5 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001706 ! cytoskeletal adaptor activity relationship: has_function CCO:F0006157 ! syndecan binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000452 ! interleukin-5 receptor complex relationship: located_in CCO:C0000464 ! adherens junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0054332 ! SDCB1_HUMAN [Term] id: CCO:B0070368 name: SDS3_HUMAN-Phosphoserine237 def: "Protein SDS3_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q9H7L9] xref: UniProtKB:Q9H7L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:B0070369 name: SELS_HUMAN-Phosphoserine140 def: "Protein SELS_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q9BQE4] xref: UniProtKB:Q9BQE4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058480 ! SELS_HUMAN [Term] id: CCO:B0070370 name: SEM4D_HUMAN-Phosphoserine195 def: "Protein SEM4D_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:Q92854] xref: UniProtKB:Q92854 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001407 ! receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058107 ! SEM4D_HUMAN [Term] id: CCO:B0070371 name: SEP10_HUMAN-Phosphoserine451 def: "Protein SEP10_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:Q9P0V9] xref: UniProtKB:Q9P0V9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001135 ! septin complex relationship: transformation_of CCO:B0002183 ! SEP10_HUMAN [Term] id: CCO:B0070372 name: SEPT2_HUMAN-Phosphotyrosine211 def: "Protein SEPT2_HUMAN with the residue 211 substituted with Phosphotyrosine" [UniProtKB:Q15019] xref: UniProtKB:Q15019 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001800 ! SEPT2_HUMAN [Term] id: CCO:B0070373 name: SEPT7_HUMAN-Phosphoserine424 def: "Protein SEPT7_HUMAN with the residue 424 substituted with Phosphoserine" [UniProtKB:Q16181] xref: UniProtKB:Q16181 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001816 ! SEPT7_HUMAN [Term] id: CCO:B0070374 name: SEPT9_HUMAN-Phosphothreonine38 def: "Protein SEPT9_HUMAN with the residue 38 substituted with Phosphothreonine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0070375 name: SEPT9_HUMAN-Phosphotyrosine278 def: "Protein SEPT9_HUMAN with the residue 278 substituted with Phosphotyrosine" [UniProtKB:Q9UHD8] xref: UniProtKB:Q9UHD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002201 ! SEPT9_HUMAN [Term] id: CCO:B0070376 name: SERA_HUMAN-N-acetylalanine2 def: "Protein SERA_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:O43175] xref: UniProtKB:O43175 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000996 ! phosphoglycerate dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0007309 ! cofactor binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063100 ! SERA_HUMAN [Term] id: CCO:B0070377 name: SERC3_HUMAN-Phosphoserine371 def: "Protein SERC3_HUMAN with the residue 371 substituted with Phosphoserine" [UniProtKB:Q13530] comment: By similarity xref: UniProtKB:Q13530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055925 ! SERC3_HUMAN [Term] id: CCO:B0070378 name: SETD2_HUMAN-Phosphoserine624 def: "Protein SETD2_HUMAN with the residue 624 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070379 name: SETD2_HUMAN-Phosphoserine742 def: "Protein SETD2_HUMAN with the residue 742 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070380 name: SETD2_HUMAN-Phosphoserine754 def: "Protein SETD2_HUMAN with the residue 754 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070381 name: SETD2_HUMAN-Phosphoserine1415 def: "Protein SETD2_HUMAN with the residue 1415 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070382 name: SETD2_HUMAN-Phosphoserine1417 def: "Protein SETD2_HUMAN with the residue 1417 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070383 name: SETD2_HUMAN-Phosphothreonine1872 def: "Protein SETD2_HUMAN with the residue 1872 substituted with Phosphothreonine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006268 ! transition metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070384 name: SETD2_HUMAN-Phosphoserine2080 def: "Protein SETD2_HUMAN with the residue 2080 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070385 name: SETD2_HUMAN-Phosphoserine2082 def: "Protein SETD2_HUMAN with the residue 2082 substituted with Phosphoserine" [UniProtKB:Q9BYW2] xref: UniProtKB:Q9BYW2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014847 ! SETD2_HUMAN [Term] id: CCO:B0070386 name: SETD8_HUMAN-Phosphoserine100 def: "Protein SETD8_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:Q9NQR1] xref: UniProtKB:Q9NQR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0035938 ! SETD8_HUMAN [Term] id: CCO:B0070387 name: SF01_HUMAN-N-acetylalanine2 def: "Protein SF01_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q15637] xref: UniProtKB:Q15637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:B0070388 name: SF01_HUMAN-Phosphoserine20 def: "Protein SF01_HUMAN with the residue 20 substituted with Phosphoserine" [UniProtKB:Q15637] comment: by PKG; xref: UniProtKB:Q15637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000407 ! ribosome relationship: transformation_of CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:B0070389 name: SF01_HUMAN-Phosphoserine80 def: "Protein SF01_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q15637] xref: UniProtKB:Q15637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:B0070390 name: SF01_HUMAN-Phosphoserine82 def: "Protein SF01_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q15637] xref: UniProtKB:Q15637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:B0070391 name: SF01_HUMAN-Phosphotyrosine87 def: "Protein SF01_HUMAN with the residue 87 substituted with Phosphotyrosine" [UniProtKB:Q15637] xref: UniProtKB:Q15637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:B0070392 name: SF01_HUMAN-Phosphoserine89 def: "Protein SF01_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q15637] xref: UniProtKB:Q15637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:B0070393 name: SF17A_HUMAN-Phosphoserine537 def: "Protein SF17A_HUMAN with the residue 537 substituted with Phosphoserine" [UniProtKB:Q02040] xref: UniProtKB:Q02040 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055701 ! SF17A_HUMAN [Term] id: CCO:B0070394 name: SF17A_HUMAN-Phosphoserine633 def: "Protein SF17A_HUMAN with the residue 633 substituted with Phosphoserine" [UniProtKB:Q02040] xref: UniProtKB:Q02040 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0055701 ! SF17A_HUMAN [Term] id: CCO:B0070395 name: SF3B4_HUMAN-Phosphotyrosine16 def: "Protein SF3B4_HUMAN with the residue 16 substituted with Phosphotyrosine" [UniProtKB:Q15427] xref: UniProtKB:Q15427 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062935 ! SF3B4_HUMAN [Term] id: CCO:B0070396 name: SF3B4_HUMAN-Phosphotyrosine56 def: "Protein SF3B4_HUMAN with the residue 56 substituted with Phosphotyrosine" [UniProtKB:Q15427] xref: UniProtKB:Q15427 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: transformation_of CCO:B0062935 ! SF3B4_HUMAN [Term] id: CCO:B0070397 name: SFPQ_HUMAN-Phosphothreonine687 def: "Protein SFPQ_HUMAN with the residue 687 substituted with Phosphothreonine" [UniProtKB:P23246] xref: UniProtKB:P23246 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:B0070398 name: SFR14_HUMAN-Phosphothreonine7 def: "Protein SFR14_HUMAN with the residue 7 substituted with Phosphothreonine" [UniProtKB:Q8IX01] xref: UniProtKB:Q8IX01 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063335 ! SFR14_HUMAN [Term] id: CCO:B0070399 name: SFR14_HUMAN-Phosphothreonine275 def: "Protein SFR14_HUMAN with the residue 275 substituted with Phosphothreonine" [UniProtKB:Q8IX01] xref: UniProtKB:Q8IX01 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063335 ! SFR14_HUMAN [Term] id: CCO:B0070400 name: SFR14_HUMAN-Phosphoserine277 def: "Protein SFR14_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q8IX01] xref: UniProtKB:Q8IX01 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063335 ! SFR14_HUMAN [Term] id: CCO:B0070401 name: SFR14_HUMAN-Phosphoserine315 def: "Protein SFR14_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q8IX01] xref: UniProtKB:Q8IX01 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063335 ! SFR14_HUMAN [Term] id: CCO:B0070402 name: SFR14_HUMAN-Phosphoserine940 def: "Protein SFR14_HUMAN with the residue 940 substituted with Phosphoserine" [UniProtKB:Q8IX01] xref: UniProtKB:Q8IX01 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063335 ! SFR14_HUMAN [Term] id: CCO:B0070403 name: SFR16_HUMAN-Phosphoserine270 def: "Protein SFR16_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070404 name: SFR16_HUMAN-Phosphoserine279 def: "Protein SFR16_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070405 name: SFR16_HUMAN-Phosphoserine302 def: "Protein SFR16_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070406 name: SFR16_HUMAN-Phosphothreonine304 def: "Protein SFR16_HUMAN with the residue 304 substituted with Phosphothreonine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070407 name: SFR16_HUMAN-Phosphoserine316 def: "Protein SFR16_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070408 name: SFR16_HUMAN-Phosphoserine320 def: "Protein SFR16_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070409 name: SFR16_HUMAN-Phosphoserine516 def: "Protein SFR16_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070410 name: SFR16_HUMAN-Phosphoserine518 def: "Protein SFR16_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070411 name: SFR16_HUMAN-Phosphoserine520 def: "Protein SFR16_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070412 name: SFR16_HUMAN-Phosphoserine532 def: "Protein SFR16_HUMAN with the residue 532 substituted with Phosphoserine" [UniProtKB:Q8N2M8] xref: UniProtKB:Q8N2M8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:B0070413 name: SFRP2_HUMAN-Phosphoserine289 def: "Protein SFRP2_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q96HF1] xref: UniProtKB:Q96HF1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058221 ! SFRP2_HUMAN [Term] id: CCO:B0070414 name: SFRS1_HUMAN-Phosphotyrosine202 def: "Protein SFRS1_HUMAN with the residue 202 substituted with Phosphotyrosine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0070415 name: SFRS1_HUMAN-Phosphoserine234 def: "Protein SFRS1_HUMAN with the residue 234 substituted with Phosphoserine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0070416 name: SFRS1_HUMAN-Phosphotyrosine237 def: "Protein SFRS1_HUMAN with the residue 237 substituted with Phosphotyrosine" [UniProtKB:Q07955] xref: UniProtKB:Q07955 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:B0070417 name: SFRS2_HUMAN-N-acetylserine2 def: "Protein SFRS2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070418 name: SFRS2_HUMAN-Phosphotyrosine23 def: "Protein SFRS2_HUMAN with the residue 23 substituted with Phosphotyrosine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070419 name: SFRS2_HUMAN-Phosphoserine26 def: "Protein SFRS2_HUMAN with the residue 26 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070420 name: SFRS2_HUMAN-Phosphoserine187 def: "Protein SFRS2_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070421 name: SFRS2_HUMAN-Phosphoserine189 def: "Protein SFRS2_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070422 name: SFRS2_HUMAN-Phosphoserine191 def: "Protein SFRS2_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070423 name: SFRS2_HUMAN-Phosphoserine204 def: "Protein SFRS2_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070424 name: SFRS2_HUMAN-Phosphoserine206 def: "Protein SFRS2_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070425 name: SFRS2_HUMAN-Phosphoserine208 def: "Protein SFRS2_HUMAN with the residue 208 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070426 name: SFRS2_HUMAN-Phosphoserine212 def: "Protein SFRS2_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070427 name: SFRS2_HUMAN-Phosphoserine220 def: "Protein SFRS2_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070428 name: SFRS2_HUMAN-Phosphoserine221 def: "Protein SFRS2_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:Q01130] xref: UniProtKB:Q01130 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:B0070429 name: SFRS5_HUMAN-Phosphoserine117 def: "Protein SFRS5_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q13243] xref: UniProtKB:Q13243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031760 ! SFRS5_HUMAN [Term] id: CCO:B0070430 name: SFRS5_HUMAN-Phosphoserine227 def: "Protein SFRS5_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q13243] xref: UniProtKB:Q13243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031760 ! SFRS5_HUMAN [Term] id: CCO:B0070431 name: SFRS5_HUMAN-Phosphoserine229 def: "Protein SFRS5_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:Q13243] xref: UniProtKB:Q13243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031760 ! SFRS5_HUMAN [Term] id: CCO:B0070432 name: SFRS5_HUMAN-Phosphoserine231 def: "Protein SFRS5_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q13243] xref: UniProtKB:Q13243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0031760 ! SFRS5_HUMAN [Term] id: CCO:B0070433 name: SFRS5_HUMAN-Phosphoserine233 def: "Protein SFRS5_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:Q13243] xref: UniProtKB:Q13243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031760 ! SFRS5_HUMAN [Term] id: CCO:B0070434 name: SFRS5_HUMAN-Phosphoserine250 def: "Protein SFRS5_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:Q13243] xref: UniProtKB:Q13243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031760 ! SFRS5_HUMAN [Term] id: CCO:B0070435 name: SFRS5_HUMAN-Phosphoserine253 def: "Protein SFRS5_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:Q13243] xref: UniProtKB:Q13243 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0031760 ! SFRS5_HUMAN [Term] id: CCO:B0070436 name: SFRS8_HUMAN-Phosphoserine283 def: "Protein SFRS8_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:Q12872] xref: UniProtKB:Q12872 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055853 ! SFRS8_HUMAN [Term] id: CCO:B0070437 name: SFRS8_HUMAN-Phosphoserine604 def: "Protein SFRS8_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:Q12872] xref: UniProtKB:Q12872 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055853 ! SFRS8_HUMAN [Term] id: CCO:B0070438 name: SFRS8_HUMAN-Phosphothreonine642 def: "Protein SFRS8_HUMAN with the residue 642 substituted with Phosphothreonine" [UniProtKB:Q12872] xref: UniProtKB:Q12872 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055853 ! SFRS8_HUMAN [Term] id: CCO:B0070439 name: SFRS8_HUMAN-Phosphoserine834 def: "Protein SFRS8_HUMAN with the residue 834 substituted with Phosphoserine" [UniProtKB:Q12872] xref: UniProtKB:Q12872 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055853 ! SFRS8_HUMAN [Term] id: CCO:B0070440 name: SFRS8_HUMAN-Phosphoserine866 def: "Protein SFRS8_HUMAN with the residue 866 substituted with Phosphoserine" [UniProtKB:Q12872] xref: UniProtKB:Q12872 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055853 ! SFRS8_HUMAN [Term] id: CCO:B0070441 name: SFRS8_HUMAN-Phosphoserine870 def: "Protein SFRS8_HUMAN with the residue 870 substituted with Phosphoserine" [UniProtKB:Q12872] xref: UniProtKB:Q12872 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055853 ! SFRS8_HUMAN [Term] id: CCO:B0070442 name: SFRS8_HUMAN-Phosphoserine909 def: "Protein SFRS8_HUMAN with the residue 909 substituted with Phosphoserine" [UniProtKB:Q12872] xref: UniProtKB:Q12872 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055853 ! SFRS8_HUMAN [Term] id: CCO:B0070443 name: SFTPD_HUMAN-4-hydroxyproline78 def: "Protein SFTPD_HUMAN with the residue 78 substituted with 4-hydroxyproline" [UniProtKB:P35247] comment: By similarity xref: UniProtKB:P35247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055282 ! SFTPD_HUMAN [Term] id: CCO:B0070444 name: SFTPD_HUMAN-5-hydroxylysine87 def: "Protein SFTPD_HUMAN with the residue 87 substituted with 5-hydroxylysine" [UniProtKB:P35247] comment: By similarity xref: UniProtKB:P35247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055282 ! SFTPD_HUMAN [Term] id: CCO:B0070445 name: SFTPD_HUMAN-4-hydroxyproline96 def: "Protein SFTPD_HUMAN with the residue 96 substituted with 4-hydroxyproline" [UniProtKB:P35247] comment: By similarity xref: UniProtKB:P35247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055282 ! SFTPD_HUMAN [Term] id: CCO:B0070446 name: SFTPD_HUMAN-5-hydroxylysine99 def: "Protein SFTPD_HUMAN with the residue 99 substituted with 5-hydroxylysine" [UniProtKB:P35247] comment: By similarity xref: UniProtKB:P35247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055282 ! SFTPD_HUMAN [Term] id: CCO:B0070447 name: SFTPD_HUMAN-4-hydroxyproline171 def: "Protein SFTPD_HUMAN with the residue 171 substituted with 4-hydroxyproline" [UniProtKB:P35247] comment: By similarity xref: UniProtKB:P35247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055282 ! SFTPD_HUMAN [Term] id: CCO:B0070448 name: SFTPD_HUMAN-4-hydroxyproline177 def: "Protein SFTPD_HUMAN with the residue 177 substituted with 4-hydroxyproline" [UniProtKB:P35247] comment: By similarity xref: UniProtKB:P35247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055282 ! SFTPD_HUMAN [Term] id: CCO:B0070449 name: SFXN1_HUMAN-N-acetylserine2 def: "Protein SFXN1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q9H9B4] xref: UniProtKB:Q9H9B4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063062 ! SFXN1_HUMAN [Term] id: CCO:B0070450 name: SGOL1_HUMAN-Phosphoserine256 def: "Protein SGOL1_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q5FBB7] xref: UniProtKB:Q5FBB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001847 ! SGOL1_HUMAN [Term] id: CCO:B0070451 name: SGOL1_HUMAN-Phosphoserine507 def: "Protein SGOL1_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:Q5FBB7] xref: UniProtKB:Q5FBB7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001847 ! SGOL1_HUMAN [Term] id: CCO:B0070452 name: SGOL2_HUMAN-Phosphoserine1144 def: "Protein SGOL2_HUMAN with the residue 1144 substituted with Phosphoserine" [UniProtKB:Q562F6] xref: UniProtKB:Q562F6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001840 ! SGOL2_HUMAN [Term] id: CCO:B0070453 name: SGOL2_HUMAN-Phosphoserine1150 def: "Protein SGOL2_HUMAN with the residue 1150 substituted with Phosphoserine" [UniProtKB:Q562F6] xref: UniProtKB:Q562F6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001840 ! SGOL2_HUMAN [Term] id: CCO:B0070454 name: SGOL2_HUMAN-Phosphoserine1151 def: "Protein SGOL2_HUMAN with the residue 1151 substituted with Phosphoserine" [UniProtKB:Q562F6] xref: UniProtKB:Q562F6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001840 ! SGOL2_HUMAN [Term] id: CCO:B0070455 name: SGT1_HUMAN-Phosphoserine503 def: "Protein SGT1_HUMAN with the residue 503 substituted with Phosphoserine" [UniProtKB:O95905] xref: UniProtKB:O95905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054803 ! SGT1_HUMAN [Term] id: CCO:B0070456 name: SGT1_HUMAN-Phosphoserine505 def: "Protein SGT1_HUMAN with the residue 505 substituted with Phosphoserine" [UniProtKB:O95905] xref: UniProtKB:O95905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054803 ! SGT1_HUMAN [Term] id: CCO:B0070457 name: SGT1_HUMAN-Phosphoserine518 def: "Protein SGT1_HUMAN with the residue 518 substituted with Phosphoserine" [UniProtKB:O95905] xref: UniProtKB:O95905 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054803 ! SGT1_HUMAN [Term] id: CCO:B0070458 name: SH22A_HUMAN-Phosphoserine217 def: "Protein SH22A_HUMAN with the residue 217 substituted with Phosphoserine" [UniProtKB:Q9NP31] xref: UniProtKB:Q9NP31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005476 ! SH22A_HUMAN [Term] id: CCO:B0070459 name: SH22A_HUMAN-Phosphoserine296 def: "Protein SH22A_HUMAN with the residue 296 substituted with Phosphoserine" [UniProtKB:Q9NP31] xref: UniProtKB:Q9NP31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005476 ! SH22A_HUMAN [Term] id: CCO:B0070460 name: SH23A_HUMAN-Phosphoserine123 def: "Protein SH23A_HUMAN with the residue 123 substituted with Phosphoserine" [UniProtKB:Q9BRG2] xref: UniProtKB:Q9BRG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058491 ! SH23A_HUMAN [Term] id: CCO:B0070461 name: SH23A_HUMAN-Phosphoserine125 def: "Protein SH23A_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q9BRG2] xref: UniProtKB:Q9BRG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058491 ! SH23A_HUMAN [Term] id: CCO:B0070462 name: SH23A_HUMAN-Phosphoserine180 def: "Protein SH23A_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:Q9BRG2] xref: UniProtKB:Q9BRG2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058491 ! SH23A_HUMAN [Term] id: CCO:B0070463 name: SH2B1_HUMAN-Phosphoserine88 def: "Protein SH2B1_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q9NRF2] xref: UniProtKB:Q9NRF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058899 ! SH2B1_HUMAN [Term] id: CCO:B0070464 name: SH2B1_HUMAN-Phosphoserine96 def: "Protein SH2B1_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q9NRF2] xref: UniProtKB:Q9NRF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058899 ! SH2B1_HUMAN [Term] id: CCO:B0070465 name: SH2B1_HUMAN-Phosphoserine125 def: "Protein SH2B1_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q9NRF2] comment: By similarity xref: UniProtKB:Q9NRF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058899 ! SH2B1_HUMAN [Term] id: CCO:B0070466 name: SH2B1_HUMAN-Phosphoserine126 def: "Protein SH2B1_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q9NRF2] comment: By similarity xref: UniProtKB:Q9NRF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058899 ! SH2B1_HUMAN [Term] id: CCO:B0070467 name: SH2B1_HUMAN-Phosphotyrosine439 def: "Protein SH2B1_HUMAN with the residue 439 substituted with Phosphotyrosine" [UniProtKB:Q9NRF2] comment: by JAK1, JAK2 and PDGFR; By similarity xref: UniProtKB:Q9NRF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058899 ! SH2B1_HUMAN [Term] id: CCO:B0070468 name: SH2B1_HUMAN-Phosphotyrosine494 def: "Protein SH2B1_HUMAN with the residue 494 substituted with Phosphotyrosine" [UniProtKB:Q9NRF2] comment: by JAK1, JAK2; By similarity xref: UniProtKB:Q9NRF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058899 ! SH2B1_HUMAN [Term] id: CCO:B0070469 name: SH2B2_HUMAN-Phosphotyrosine629 def: "Protein SH2B2_HUMAN with the residue 629 substituted with Phosphotyrosine" [UniProtKB:O14492] xref: UniProtKB:O14492 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001378 ! transmembrane receptor protein tyrosine kinase adaptor protein activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001809 ! JAK pathway signal transduction adaptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000181 ! ruffle relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000442 ! actin filament relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054343 ! SH2B2_HUMAN [Term] id: CCO:B0070470 name: SH2D3_HUMAN-Phosphotyrosine183 def: "Protein SH2D3_HUMAN with the residue 183 substituted with Phosphotyrosine" [UniProtKB:Q8N5H7] xref: UniProtKB:Q8N5H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057474 ! SH2D3_HUMAN [Term] id: CCO:B0070471 name: SH2D3_HUMAN-Phosphotyrosine278 def: "Protein SH2D3_HUMAN with the residue 278 substituted with Phosphotyrosine" [UniProtKB:Q8N5H7] comment: By similarity xref: UniProtKB:Q8N5H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057474 ! SH2D3_HUMAN [Term] id: CCO:B0070472 name: SH2D3_HUMAN-Phosphotyrosine283 def: "Protein SH2D3_HUMAN with the residue 283 substituted with Phosphotyrosine" [UniProtKB:Q8N5H7] comment: By similarity xref: UniProtKB:Q8N5H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057474 ! SH2D3_HUMAN [Term] id: CCO:B0070473 name: SH2D3_HUMAN-Phosphotyrosine793 def: "Protein SH2D3_HUMAN with the residue 793 substituted with Phosphotyrosine" [UniProtKB:Q8N5H7] comment: By similarity xref: UniProtKB:Q8N5H7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057474 ! SH2D3_HUMAN [Term] id: CCO:B0070474 name: SH3B4_HUMAN-Phosphoserine246 def: "Protein SH3B4_HUMAN with the residue 246 substituted with Phosphoserine" [UniProtKB:Q9P0V3] xref: UniProtKB:Q9P0V3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002182 ! SH3B4_HUMAN [Term] id: CCO:B0070475 name: SHAN2_HUMAN-Phosphoserine364 def: "Protein SHAN2_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:Q9UPX8] comment: By similarity xref: UniProtKB:Q9UPX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059272 ! SHAN2_HUMAN [Term] id: CCO:B0070476 name: SHAN2_HUMAN-Phosphothreonine509 def: "Protein SHAN2_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q9UPX8] comment: By similarity xref: UniProtKB:Q9UPX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059272 ! SHAN2_HUMAN [Term] id: CCO:B0070477 name: SHAN2_HUMAN-Phosphothreonine682 def: "Protein SHAN2_HUMAN with the residue 682 substituted with Phosphothreonine" [UniProtKB:Q9UPX8] comment: By similarity xref: UniProtKB:Q9UPX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059272 ! SHAN2_HUMAN [Term] id: CCO:B0070478 name: SHAN2_HUMAN-Phosphoserine1052 def: "Protein SHAN2_HUMAN with the residue 1052 substituted with Phosphoserine" [UniProtKB:Q9UPX8] xref: UniProtKB:Q9UPX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059272 ! SHAN2_HUMAN [Term] id: CCO:B0070479 name: SHAN2_HUMAN-Phosphoserine1113 def: "Protein SHAN2_HUMAN with the residue 1113 substituted with Phosphoserine" [UniProtKB:Q9UPX8] comment: By similarity xref: UniProtKB:Q9UPX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004333 ! GKAP/Homer scaffold activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0059272 ! SHAN2_HUMAN [Term] id: CCO:B0070480 name: SHAN2_HUMAN-Phosphoserine1117 def: "Protein SHAN2_HUMAN with the residue 1117 substituted with Phosphoserine" [UniProtKB:Q9UPX8] comment: By similarity xref: UniProtKB:Q9UPX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059272 ! SHAN2_HUMAN [Term] id: CCO:B0070481 name: SHAN2_HUMAN-Phosphothreonine1119 def: "Protein SHAN2_HUMAN with the residue 1119 substituted with Phosphothreonine" [UniProtKB:Q9UPX8] comment: By similarity xref: UniProtKB:Q9UPX8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059272 ! SHAN2_HUMAN [Term] id: CCO:B0070482 name: SHAN3_HUMAN-Phosphotyrosine122 def: "Protein SHAN3_HUMAN with the residue 122 substituted with Phosphotyrosine" [UniProtKB:Q9BYB0] comment: By similarity xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070483 name: SHAN3_HUMAN-Phosphoserine375 def: "Protein SHAN3_HUMAN with the residue 375 substituted with Phosphoserine" [UniProtKB:Q9BYB0] comment: By similarity xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070484 name: SHAN3_HUMAN-Phosphotyrosine557 def: "Protein SHAN3_HUMAN with the residue 557 substituted with Phosphotyrosine" [UniProtKB:Q9BYB0] comment: By similarity xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070485 name: SHAN3_HUMAN-Phosphotyrosine566 def: "Protein SHAN3_HUMAN with the residue 566 substituted with Phosphotyrosine" [UniProtKB:Q9BYB0] comment: By similarity xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070486 name: SHAN3_HUMAN-Phosphoserine783 def: "Protein SHAN3_HUMAN with the residue 783 substituted with Phosphoserine" [UniProtKB:Q9BYB0] comment: By similarity xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: located_in CCO:C0001902 ! postsynaptic membrane relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070487 name: SHAN3_HUMAN-Phosphoserine1159 def: "Protein SHAN3_HUMAN with the residue 1159 substituted with Phosphoserine" [UniProtKB:Q9BYB0] xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070488 name: SHAN3_HUMAN-Phosphoserine1163 def: "Protein SHAN3_HUMAN with the residue 1163 substituted with Phosphoserine" [UniProtKB:Q9BYB0] xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070489 name: SHAN3_HUMAN-Phosphoserine1644 def: "Protein SHAN3_HUMAN with the residue 1644 substituted with Phosphoserine" [UniProtKB:Q9BYB0] comment: By similarity xref: UniProtKB:Q9BYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058573 ! SHAN3_HUMAN [Term] id: CCO:B0070490 name: SHB_HUMAN-Phosphotyrosine114 def: "Protein SHB_HUMAN with the residue 114 substituted with Phosphotyrosine" [UniProtKB:Q15464] comment: By similarity xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070491 name: SHB_HUMAN-Phosphoserine156 def: "Protein SHB_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q15464] comment: By similarity xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070492 name: SHB_HUMAN-Phosphotyrosine246 def: "Protein SHB_HUMAN with the residue 246 substituted with Phosphotyrosine" [UniProtKB:Q15464] xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070493 name: SHB_HUMAN-Phosphotyrosine268 def: "Protein SHB_HUMAN with the residue 268 substituted with Phosphotyrosine" [UniProtKB:Q15464] comment: By similarity xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070494 name: SHB_HUMAN-Phosphoserine314 def: "Protein SHB_HUMAN with the residue 314 substituted with Phosphoserine" [UniProtKB:Q15464] xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070495 name: SHB_HUMAN-Phosphoserine317 def: "Protein SHB_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q15464] xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070496 name: SHB_HUMAN-Phosphotyrosine336 def: "Protein SHB_HUMAN with the residue 336 substituted with Phosphotyrosine" [UniProtKB:Q15464] comment: By similarity xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070497 name: SHB_HUMAN-Phosphoserine388 def: "Protein SHB_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q15464] xref: UniProtKB:Q15464 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056065 ! SHB_HUMAN [Term] id: CCO:B0070498 name: SHC2_HUMAN-Phosphotyrosine338 def: "Protein SHC2_HUMAN with the residue 338 substituted with Phosphotyrosine" [UniProtKB:P98077] comment: Probable xref: UniProtKB:P98077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055667 ! SHC2_HUMAN [Term] id: CCO:B0070499 name: SHC2_HUMAN-Phosphotyrosine339 def: "Protein SHC2_HUMAN with the residue 339 substituted with Phosphotyrosine" [UniProtKB:P98077] comment: Probable xref: UniProtKB:P98077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055667 ! SHC2_HUMAN [Term] id: CCO:B0070500 name: SHC2_HUMAN-Phosphotyrosine414 def: "Protein SHC2_HUMAN with the residue 414 substituted with Phosphotyrosine" [UniProtKB:P98077] comment: Probable xref: UniProtKB:P98077 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055667 ! SHC2_HUMAN [Term] id: CCO:B0070501 name: SHC4_HUMAN-Phosphotyrosine424 def: "Protein SHC4_HUMAN with the residue 424 substituted with Phosphotyrosine" [UniProtKB:Q6S5L8] xref: UniProtKB:Q6S5L8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056938 ! SHC4_HUMAN [Term] id: CCO:B0070502 name: SHIP1_HUMAN-Phosphotyrosine865 def: "Protein SHIP1_HUMAN with the residue 865 substituted with Phosphotyrosine" [UniProtKB:Q92835] xref: UniProtKB:Q92835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058100 ! SHIP1_HUMAN [Term] id: CCO:B0070503 name: SHIP1_HUMAN-Phosphotyrosine915 def: "Protein SHIP1_HUMAN with the residue 915 substituted with Phosphotyrosine" [UniProtKB:Q92835] xref: UniProtKB:Q92835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058100 ! SHIP1_HUMAN [Term] id: CCO:B0070504 name: SHIP1_HUMAN-Phosphoserine934 def: "Protein SHIP1_HUMAN with the residue 934 substituted with Phosphoserine" [UniProtKB:Q92835] comment: By similarity xref: UniProtKB:Q92835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058100 ! SHIP1_HUMAN [Term] id: CCO:B0070505 name: SHIP1_HUMAN-Phosphotyrosine944 def: "Protein SHIP1_HUMAN with the residue 944 substituted with Phosphotyrosine" [UniProtKB:Q92835] comment: By similarity xref: UniProtKB:Q92835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0000845 ! inositol-polyphosphate 5-phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0008387 ! phosphatase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058100 ! SHIP1_HUMAN [Term] id: CCO:B0070506 name: SHIP1_HUMAN-Phosphotyrosine1022 def: "Protein SHIP1_HUMAN with the residue 1022 substituted with Phosphotyrosine" [UniProtKB:Q92835] xref: UniProtKB:Q92835 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058100 ! SHIP1_HUMAN [Term] id: CCO:B0070507 name: SHPS1_HUMAN-Phosphotyrosine428 def: "Protein SHPS1_HUMAN with the residue 428 substituted with Phosphotyrosine" [UniProtKB:P78324] comment: by Tyr-kinases; Potential xref: UniProtKB:P78324 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062831 ! SHPS1_HUMAN [Term] id: CCO:B0070508 name: SHPS1_HUMAN-Phosphotyrosine452 def: "Protein SHPS1_HUMAN with the residue 452 substituted with Phosphotyrosine" [UniProtKB:P78324] comment: by Tyr-kinases; Potential xref: UniProtKB:P78324 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062831 ! SHPS1_HUMAN [Term] id: CCO:B0070509 name: SHPS1_HUMAN-Phosphotyrosine469 def: "Protein SHPS1_HUMAN with the residue 469 substituted with Phosphotyrosine" [UniProtKB:P78324] comment: by Tyr-kinases; By similarity xref: UniProtKB:P78324 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062831 ! SHPS1_HUMAN [Term] id: CCO:B0070510 name: SHPS1_HUMAN-Phosphotyrosine495 def: "Protein SHPS1_HUMAN with the residue 495 substituted with Phosphotyrosine" [UniProtKB:P78324] comment: by Tyr-kinases; By similarity xref: UniProtKB:P78324 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0062831 ! SHPS1_HUMAN [Term] id: CCO:B0070511 name: SHRM3_HUMAN-Phosphoserine438 def: "Protein SHRM3_HUMAN with the residue 438 substituted with Phosphoserine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070512 name: SHRM3_HUMAN-Phosphoserine442 def: "Protein SHRM3_HUMAN with the residue 442 substituted with Phosphoserine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070513 name: SHRM3_HUMAN-Phosphothreonine575 def: "Protein SHRM3_HUMAN with the residue 575 substituted with Phosphothreonine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070514 name: SHRM3_HUMAN-Phosphoserine581 def: "Protein SHRM3_HUMAN with the residue 581 substituted with Phosphoserine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070515 name: SHRM3_HUMAN-Phosphoserine584 def: "Protein SHRM3_HUMAN with the residue 584 substituted with Phosphoserine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000464 ! adherens junction relationship: located_in CCO:C0000781 ! apical plasma membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001769 ! apical junction complex relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070516 name: SHRM3_HUMAN-Phosphoserine889 def: "Protein SHRM3_HUMAN with the residue 889 substituted with Phosphoserine" [UniProtKB:Q8TF72] comment: By similarity xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070517 name: SHRM3_HUMAN-Phosphoserine909 def: "Protein SHRM3_HUMAN with the residue 909 substituted with Phosphoserine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070518 name: SHRM3_HUMAN-Phosphoserine912 def: "Protein SHRM3_HUMAN with the residue 912 substituted with Phosphoserine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070519 name: SHRM3_HUMAN-Phosphoserine1220 def: "Protein SHRM3_HUMAN with the residue 1220 substituted with Phosphoserine" [UniProtKB:Q8TF72] xref: UniProtKB:Q8TF72 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057967 ! SHRM3_HUMAN [Term] id: CCO:B0070520 name: SI1L1_HUMAN-Phosphoserine161 def: "Protein SI1L1_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:O43166] xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070521 name: SI1L1_HUMAN-Phosphoserine1257 def: "Protein SI1L1_HUMAN with the residue 1257 substituted with Phosphoserine" [UniProtKB:O43166] xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070522 name: SI1L1_HUMAN-Phosphoserine1270 def: "Protein SI1L1_HUMAN with the residue 1270 substituted with Phosphoserine" [UniProtKB:O43166] xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070523 name: SI1L1_HUMAN-Phosphoserine1433 def: "Protein SI1L1_HUMAN with the residue 1433 substituted with Phosphoserine" [UniProtKB:O43166] xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070524 name: SI1L1_HUMAN-Phosphoserine1528 def: "Protein SI1L1_HUMAN with the residue 1528 substituted with Phosphoserine" [UniProtKB:O43166] xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070525 name: SI1L1_HUMAN-Phosphoserine1549 def: "Protein SI1L1_HUMAN with the residue 1549 substituted with Phosphoserine" [UniProtKB:O43166] xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070526 name: SI1L1_HUMAN-Phosphoserine1568 def: "Protein SI1L1_HUMAN with the residue 1568 substituted with Phosphoserine" [UniProtKB:O43166] comment: By similarity xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070527 name: SI1L1_HUMAN-Phosphoserine1585 def: "Protein SI1L1_HUMAN with the residue 1585 substituted with Phosphoserine" [UniProtKB:O43166] xref: UniProtKB:O43166 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:B0070528 name: SI1L2_HUMAN-Phosphoserine1029 def: "Protein SI1L2_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q9P2F8] xref: UniProtKB:Q9P2F8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0023489 ! SI1L2_HUMAN [Term] id: CCO:B0070529 name: SI1L2_HUMAN-Phosphoserine1488 def: "Protein SI1L2_HUMAN with the residue 1488 substituted with Phosphoserine" [UniProtKB:Q9P2F8] xref: UniProtKB:Q9P2F8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023489 ! SI1L2_HUMAN [Term] id: CCO:B0070530 name: SI1L3_HUMAN-Phosphoserine1135 def: "Protein SI1L3_HUMAN with the residue 1135 substituted with Phosphoserine" [UniProtKB:O60292] xref: UniProtKB:O60292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054542 ! SI1L3_HUMAN [Term] id: CCO:B0070531 name: SI1L3_HUMAN-Phosphotyrosine1265 def: "Protein SI1L3_HUMAN with the residue 1265 substituted with Phosphotyrosine" [UniProtKB:O60292] xref: UniProtKB:O60292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0054542 ! SI1L3_HUMAN [Term] id: CCO:B0070532 name: SI1L3_HUMAN-Phosphoserine1364 def: "Protein SI1L3_HUMAN with the residue 1364 substituted with Phosphoserine" [UniProtKB:O60292] xref: UniProtKB:O60292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054542 ! SI1L3_HUMAN [Term] id: CCO:B0070533 name: SIGIR_HUMAN-Phosphoserine380 def: "Protein SIGIR_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q6IA17] comment: By similarity xref: UniProtKB:Q6IA17 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056756 ! SIGIR_HUMAN [Term] id: CCO:B0070534 name: SIN1_HUMAN-Phosphoserine510 def: "Protein SIN1_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q9BPZ7] xref: UniProtKB:Q9BPZ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027730 ! SIN1_HUMAN [Term] id: CCO:B0070535 name: SIN3A_HUMAN-Phosphoserine10 def: "Protein SIN3A_HUMAN with the residue 10 substituted with Phosphoserine" [UniProtKB:Q96ST3] xref: UniProtKB:Q96ST3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:B0070536 name: SIN3A_HUMAN-Phosphoserine277 def: "Protein SIN3A_HUMAN with the residue 277 substituted with Phosphoserine" [UniProtKB:Q96ST3] xref: UniProtKB:Q96ST3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:B0070537 name: SIN3A_HUMAN-Phosphoserine940 def: "Protein SIN3A_HUMAN with the residue 940 substituted with Phosphoserine" [UniProtKB:Q96ST3] xref: UniProtKB:Q96ST3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:B0070538 name: SIPA1_HUMAN-Phosphoserine53 def: "Protein SIPA1_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:Q96FS4] xref: UniProtKB:Q96FS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002039 ! SIPA1_HUMAN [Term] id: CCO:B0070539 name: SIPA1_HUMAN-Phosphoserine55 def: "Protein SIPA1_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:Q96FS4] xref: UniProtKB:Q96FS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002039 ! SIPA1_HUMAN [Term] id: CCO:B0070540 name: SIPA1_HUMAN-Phosphothreonine64 def: "Protein SIPA1_HUMAN with the residue 64 substituted with Phosphothreonine" [UniProtKB:Q96FS4] xref: UniProtKB:Q96FS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002039 ! SIPA1_HUMAN [Term] id: CCO:B0070541 name: SIPA1_HUMAN-Phosphoserine67 def: "Protein SIPA1_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:Q96FS4] xref: UniProtKB:Q96FS4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002039 ! SIPA1_HUMAN [Term] id: CCO:B0070542 name: SIRT1_HUMAN-Phosphoserine27 def: "Protein SIRT1_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q96EB6] xref: UniProtKB:Q96EB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058204 ! SIRT1_HUMAN [Term] id: CCO:B0070543 name: SIRT1_HUMAN-Phosphoserine47 def: "Protein SIRT1_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q96EB6] xref: UniProtKB:Q96EB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000443 ! NAD+ ADP-ribosyltransferase activity relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0004136 ! deacetylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: transformation_of CCO:B0058204 ! SIRT1_HUMAN [Term] id: CCO:B0070544 name: SIRT1_HUMAN-Phosphothreonine719 def: "Protein SIRT1_HUMAN with the residue 719 substituted with Phosphothreonine" [UniProtKB:Q96EB6] xref: UniProtKB:Q96EB6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058204 ! SIRT1_HUMAN [Term] id: CCO:B0070545 name: SIRT4_HUMAN-Phosphoserine255 def: "Protein SIRT4_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:Q9Y6E7] xref: UniProtKB:Q9Y6E7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059404 ! SIRT4_HUMAN [Term] id: CCO:B0070546 name: SIRT4_HUMAN-Phosphoserine261 def: "Protein SIRT4_HUMAN with the residue 261 substituted with Phosphoserine" [UniProtKB:Q9Y6E7] xref: UniProtKB:Q9Y6E7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059404 ! SIRT4_HUMAN [Term] id: CCO:B0070547 name: SIRT4_HUMAN-Phosphoserine262 def: "Protein SIRT4_HUMAN with the residue 262 substituted with Phosphoserine" [UniProtKB:Q9Y6E7] xref: UniProtKB:Q9Y6E7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059404 ! SIRT4_HUMAN [Term] id: CCO:B0070548 name: SIRT6_HUMAN-Phosphothreonine294 def: "Protein SIRT6_HUMAN with the residue 294 substituted with Phosphothreonine" [UniProtKB:Q8N6T7] xref: UniProtKB:Q8N6T7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000449 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003332 ! transferase activity, transferring glycosyl groups relationship: has_function CCO:F0003591 ! NAD-dependent histone deacetylase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000280 ! chromatin silencing complex relationship: transformation_of CCO:B0057492 ! SIRT6_HUMAN [Term] id: CCO:B0070549 name: SIRT6_HUMAN-Phosphoserine303 def: "Protein SIRT6_HUMAN with the residue 303 substituted with Phosphoserine" [UniProtKB:Q8N6T7] xref: UniProtKB:Q8N6T7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057492 ! SIRT6_HUMAN [Term] id: CCO:B0070550 name: SIT1_HUMAN-Phosphoserine80 def: "Protein SIT1_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070551 name: SIT1_HUMAN-Phosphoserine83 def: "Protein SIT1_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070552 name: SIT1_HUMAN-Phosphotyrosine90 def: "Protein SIT1_HUMAN with the residue 90 substituted with Phosphotyrosine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070553 name: SIT1_HUMAN-Phosphotyrosine95 def: "Protein SIT1_HUMAN with the residue 95 substituted with Phosphotyrosine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070554 name: SIT1_HUMAN-Phosphothreonine98 def: "Protein SIT1_HUMAN with the residue 98 substituted with Phosphothreonine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070555 name: SIT1_HUMAN-Phosphoserine102 def: "Protein SIT1_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070556 name: SIT1_HUMAN-Phosphotyrosine127 def: "Protein SIT1_HUMAN with the residue 127 substituted with Phosphotyrosine" [UniProtKB:Q9Y3P8] comment: Probable xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004209 ! kinase binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070557 name: SIT1_HUMAN-Phosphothreonine144 def: "Protein SIT1_HUMAN with the residue 144 substituted with Phosphothreonine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070558 name: SIT1_HUMAN-Phosphotyrosine148 def: "Protein SIT1_HUMAN with the residue 148 substituted with Phosphotyrosine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070559 name: SIT1_HUMAN-Phosphoserine149 def: "Protein SIT1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070560 name: SIT1_HUMAN-Phosphotyrosine169 def: "Protein SIT1_HUMAN with the residue 169 substituted with Phosphotyrosine" [UniProtKB:Q9Y3P8] comment: Probable xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070561 name: SIT1_HUMAN-Phosphoserine182 def: "Protein SIT1_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070562 name: SIT1_HUMAN-Phosphotyrosine188 def: "Protein SIT1_HUMAN with the residue 188 substituted with Phosphotyrosine" [UniProtKB:Q9Y3P8] xref: UniProtKB:Q9Y3P8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:B0070563 name: SIVA_HUMAN-Phosphotyrosine34 def: "Protein SIVA_HUMAN with the residue 34 substituted with Phosphotyrosine" [UniProtKB:O15304] comment: by ABL2; xref: UniProtKB:O15304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000169 ! viral receptor activity relationship: has_function CCO:F0001476 ! CD27 receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0054423 ! SIVA_HUMAN [Term] id: CCO:B0070564 name: SIX4_HUMAN-Phosphoserine619 def: "Protein SIX4_HUMAN with the residue 619 substituted with Phosphoserine" [UniProtKB:Q9UIU6] xref: UniProtKB:Q9UIU6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059164 ! SIX4_HUMAN [Term] id: CCO:B0070565 name: SKAP1_HUMAN-Phosphotyrosine142 def: "Protein SKAP1_HUMAN with the residue 142 substituted with Phosphotyrosine" [UniProtKB:Q86WV1] xref: UniProtKB:Q86WV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0057281 ! SKAP1_HUMAN [Term] id: CCO:B0070566 name: SKAP1_HUMAN-Phosphotyrosine219 def: "Protein SKAP1_HUMAN with the residue 219 substituted with Phosphotyrosine" [UniProtKB:Q86WV1] comment: Probable xref: UniProtKB:Q86WV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057281 ! SKAP1_HUMAN [Term] id: CCO:B0070567 name: SKAP1_HUMAN-Phosphotyrosine232 def: "Protein SKAP1_HUMAN with the residue 232 substituted with Phosphotyrosine" [UniProtKB:Q86WV1] comment: Probable xref: UniProtKB:Q86WV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057281 ! SKAP1_HUMAN [Term] id: CCO:B0070568 name: SKAP1_HUMAN-Phosphotyrosine271 def: "Protein SKAP1_HUMAN with the residue 271 substituted with Phosphotyrosine" [UniProtKB:Q86WV1] comment: by FYN; xref: UniProtKB:Q86WV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057281 ! SKAP1_HUMAN [Term] id: CCO:B0070569 name: SKAP1_HUMAN-Phosphotyrosine295 def: "Protein SKAP1_HUMAN with the residue 295 substituted with Phosphotyrosine" [UniProtKB:Q86WV1] comment: by FYN; Probable xref: UniProtKB:Q86WV1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057281 ! SKAP1_HUMAN [Term] id: CCO:B0070570 name: SKAP2_HUMAN-Phosphotyrosine75 def: "Protein SKAP2_HUMAN with the residue 75 substituted with Phosphotyrosine" [UniProtKB:O75563] comment: By similarity xref: UniProtKB:O75563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054650 ! SKAP2_HUMAN [Term] id: CCO:B0070571 name: SKAP2_HUMAN-Phosphotyrosine151 def: "Protein SKAP2_HUMAN with the residue 151 substituted with Phosphotyrosine" [UniProtKB:O75563] xref: UniProtKB:O75563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054650 ! SKAP2_HUMAN [Term] id: CCO:B0070572 name: SKAP2_HUMAN-Phosphotyrosine197 def: "Protein SKAP2_HUMAN with the residue 197 substituted with Phosphotyrosine" [UniProtKB:O75563] xref: UniProtKB:O75563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054650 ! SKAP2_HUMAN [Term] id: CCO:B0070573 name: SKAP2_HUMAN-Phosphotyrosine261 def: "Protein SKAP2_HUMAN with the residue 261 substituted with Phosphotyrosine" [UniProtKB:O75563] comment: By similarity xref: UniProtKB:O75563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054650 ! SKAP2_HUMAN [Term] id: CCO:B0070574 name: SKAP2_HUMAN-Phosphotyrosine325 def: "Protein SKAP2_HUMAN with the residue 325 substituted with Phosphotyrosine" [UniProtKB:O75563] xref: UniProtKB:O75563 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0054650 ! SKAP2_HUMAN [Term] id: CCO:B0070575 name: SLAF1_HUMAN-Phosphotyrosine281 def: "Protein SLAF1_HUMAN with the residue 281 substituted with Phosphotyrosine" [UniProtKB:Q13291] xref: UniProtKB:Q13291 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000342 ! antigen binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000709 ! cell surface relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055894 ! SLAF1_HUMAN [Term] id: CCO:B0070576 name: SLIB_HUMAN-Leucine amide75 def: "Protein SLIB_HUMAN with the residue 75 substituted with Leucine amide" [UniProtKB:P01286] xref: UniProtKB:P01286 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054850 ! SLIB_HUMAN [Term] id: CCO:B0070577 name: SLIRP_HUMAN-Phosphoserine15 def: "Protein SLIRP_HUMAN with the residue 15 substituted with Phosphoserine" [UniProtKB:Q9GZT3] xref: UniProtKB:Q9GZT3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058635 ! SLIRP_HUMAN [Term] id: CCO:B0070578 name: SLIRP_HUMAN-Phosphoserine102 def: "Protein SLIRP_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q9GZT3] xref: UniProtKB:Q9GZT3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0058635 ! SLIRP_HUMAN [Term] id: CCO:B0070579 name: SLTM_HUMAN-Phosphoserine93 def: "Protein SLTM_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070580 name: SLTM_HUMAN-Phosphoserine97 def: "Protein SLTM_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070581 name: SLTM_HUMAN-Phosphoserine139 def: "Protein SLTM_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q9NWH9] comment: By similarity xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070582 name: SLTM_HUMAN-Phosphoserine289 def: "Protein SLTM_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070583 name: SLTM_HUMAN-Phosphoserine421 def: "Protein SLTM_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070584 name: SLTM_HUMAN-Phosphoserine550 def: "Protein SLTM_HUMAN with the residue 550 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070585 name: SLTM_HUMAN-Phosphoserine551 def: "Protein SLTM_HUMAN with the residue 551 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070586 name: SLTM_HUMAN-Phosphoserine553 def: "Protein SLTM_HUMAN with the residue 553 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070587 name: SLTM_HUMAN-Phosphoserine590 def: "Protein SLTM_HUMAN with the residue 590 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070588 name: SLTM_HUMAN-Phosphoserine1002 def: "Protein SLTM_HUMAN with the residue 1002 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070589 name: SLTM_HUMAN-Phosphoserine1014 def: "Protein SLTM_HUMAN with the residue 1014 substituted with Phosphoserine" [UniProtKB:Q9NWH9] xref: UniProtKB:Q9NWH9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058938 ! SLTM_HUMAN [Term] id: CCO:B0070590 name: SMAD1_HUMAN-Phosphoserine463 def: "Protein SMAD1_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:Q15797] xref: UniProtKB:Q15797 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056114 ! SMAD1_HUMAN [Term] id: CCO:B0070591 name: SMAD1_HUMAN-Phosphoserine465 def: "Protein SMAD1_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q15797] xref: UniProtKB:Q15797 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056114 ! SMAD1_HUMAN [Term] id: CCO:B0070592 name: SMAD2_HUMAN-Phosphothreonine8 def: "Protein SMAD2_HUMAN with the residue 8 substituted with Phosphothreonine" [UniProtKB:Q15796] comment: by MAPK3; xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070593 name: SMAD2_HUMAN-N6-acetyllysine19 def: "Protein SMAD2_HUMAN with the residue 19 substituted with N6-acetyllysine" [UniProtKB:Q15796] xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070594 name: SMAD2_HUMAN-Phosphothreonine220 def: "Protein SMAD2_HUMAN with the residue 220 substituted with Phosphothreonine" [UniProtKB:Q15796] comment: Probable xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070595 name: SMAD2_HUMAN-Phosphoserine240 def: "Protein SMAD2_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q15796] comment: by CAMK2; xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070596 name: SMAD2_HUMAN-Phosphoserine245 def: "Protein SMAD2_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:Q15796] comment: Probable xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070597 name: SMAD2_HUMAN-Phosphoserine250 def: "Protein SMAD2_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:Q15796] comment: Probable xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070598 name: SMAD2_HUMAN-Phosphoserine255 def: "Protein SMAD2_HUMAN with the residue 255 substituted with Phosphoserine" [UniProtKB:Q15796] comment: Probable xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070599 name: SMAD2_HUMAN-Phosphoserine458 def: "Protein SMAD2_HUMAN with the residue 458 substituted with Phosphoserine" [UniProtKB:Q15796] xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070600 name: SMAD2_HUMAN-Phosphoserine465 def: "Protein SMAD2_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q15796] xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070601 name: SMAD2_HUMAN-Phosphoserine467 def: "Protein SMAD2_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:Q15796] xref: UniProtKB:Q15796 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:B0070602 name: SMAD3_HUMAN-Phosphoserine416 def: "Protein SMAD3_HUMAN with the residue 416 substituted with Phosphoserine" [UniProtKB:P84022] xref: UniProtKB:P84022 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002868 ! transport accessory protein activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006174 ! SMAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001751 ! receptor complex relationship: transformation_of CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:B0070603 name: SMAD5_HUMAN-Phosphoserine133 def: "Protein SMAD5_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:Q99717] xref: UniProtKB:Q99717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058446 ! SMAD5_HUMAN [Term] id: CCO:B0070604 name: SMAD5_HUMAN-Phosphoserine463 def: "Protein SMAD5_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:Q99717] xref: UniProtKB:Q99717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058446 ! SMAD5_HUMAN [Term] id: CCO:B0070605 name: SMAD5_HUMAN-Phosphoserine465 def: "Protein SMAD5_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q99717] xref: UniProtKB:Q99717 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0058446 ! SMAD5_HUMAN [Term] id: CCO:B0070606 name: SMAD6_HUMAN-Phosphoserine435 def: "Protein SMAD6_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:O43541] xref: UniProtKB:O43541 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054488 ! SMAD6_HUMAN [Term] id: CCO:B0070607 name: SMAD7_HUMAN-N6-acetyllysine64 def: "Protein SMAD7_HUMAN with the residue 64 substituted with N6-acetyllysine" [UniProtKB:O15105] comment: alternate; xref: UniProtKB:O15105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054406 ! SMAD7_HUMAN [Term] id: CCO:B0070608 name: SMAD7_HUMAN-N6-acetyllysine70 def: "Protein SMAD7_HUMAN with the residue 70 substituted with N6-acetyllysine" [UniProtKB:O15105] comment: alternate; xref: UniProtKB:O15105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054406 ! SMAD7_HUMAN [Term] id: CCO:B0070609 name: SMAD7_HUMAN-Phosphoserine249 def: "Protein SMAD7_HUMAN with the residue 249 substituted with Phosphoserine" [UniProtKB:O15105] comment: By similarity xref: UniProtKB:O15105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054406 ! SMAD7_HUMAN [Term] id: CCO:B0070610 name: SMAD9_HUMAN-Phosphoserine465 def: "Protein SMAD9_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:O15198] xref: UniProtKB:O15198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054414 ! SMAD9_HUMAN [Term] id: CCO:B0070611 name: SMAD9_HUMAN-Phosphoserine467 def: "Protein SMAD9_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:O15198] xref: UniProtKB:O15198 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054414 ! SMAD9_HUMAN [Term] id: CCO:B0070612 name: SMBP2_HUMAN-N-acetylalanine2 def: "Protein SMBP2_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P38935] xref: UniProtKB:P38935 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055321 ! SMBP2_HUMAN [Term] id: CCO:B0070613 name: SMBP2_HUMAN-Phosphoserine656 def: "Protein SMBP2_HUMAN with the residue 656 substituted with Phosphoserine" [UniProtKB:P38935] xref: UniProtKB:P38935 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000275 ! DNA helicase activity relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003574 ! nucleoside-triphosphatase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0055321 ! SMBP2_HUMAN [Term] id: CCO:B0070614 name: SMBT1_HUMAN-Phosphoserine765 def: "Protein SMBT1_HUMAN with the residue 765 substituted with Phosphoserine" [UniProtKB:Q9UHJ3] xref: UniProtKB:Q9UHJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059142 ! SMBT1_HUMAN [Term] id: CCO:B0070615 name: SMBT1_HUMAN-Phosphoserine767 def: "Protein SMBT1_HUMAN with the residue 767 substituted with Phosphoserine" [UniProtKB:Q9UHJ3] xref: UniProtKB:Q9UHJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059142 ! SMBT1_HUMAN [Term] id: CCO:B0070616 name: SMBT1_HUMAN-Phosphoserine775 def: "Protein SMBT1_HUMAN with the residue 775 substituted with Phosphoserine" [UniProtKB:Q9UHJ3] xref: UniProtKB:Q9UHJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059142 ! SMBT1_HUMAN [Term] id: CCO:B0070617 name: SMC1A_HUMAN-Phosphoserine970 def: "Protein SMC1A_HUMAN with the residue 970 substituted with Phosphoserine" [UniProtKB:Q14683] xref: UniProtKB:Q14683 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:B0070618 name: SMC4_HUMAN-Phosphoserine27 def: "Protein SMC4_HUMAN with the residue 27 substituted with Phosphoserine" [UniProtKB:Q9NTJ3] xref: UniProtKB:Q9NTJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002168 ! SMC4_HUMAN [Term] id: CCO:B0070619 name: SMCA1_HUMAN-Phosphotyrosine954 def: "Protein SMCA1_HUMAN with the residue 954 substituted with Phosphotyrosine" [UniProtKB:P28370] xref: UniProtKB:P28370 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0004675 ! nucleosome binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000806 ! chromatin remodeling complex relationship: transformation_of CCO:B0055204 ! SMCA1_HUMAN [Term] id: CCO:B0070620 name: SMCA2_HUMAN-Phosphoserine329 def: "Protein SMCA2_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070621 name: SMCA2_HUMAN-Phosphoserine591 def: "Protein SMCA2_HUMAN with the residue 591 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070622 name: SMCA2_HUMAN-Phosphoserine956 def: "Protein SMCA2_HUMAN with the residue 956 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070623 name: SMCA2_HUMAN-Phosphoserine1377 def: "Protein SMCA2_HUMAN with the residue 1377 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070624 name: SMCA2_HUMAN-Phosphoserine1410 def: "Protein SMCA2_HUMAN with the residue 1410 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070625 name: SMCA2_HUMAN-Phosphoserine1418 def: "Protein SMCA2_HUMAN with the residue 1418 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070626 name: SMCA2_HUMAN-Phosphoserine1419 def: "Protein SMCA2_HUMAN with the residue 1419 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070627 name: SMCA2_HUMAN-N6-acetyllysine1553 def: "Protein SMCA2_HUMAN with the residue 1553 substituted with N6-acetyllysine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070628 name: SMCA2_HUMAN-N6-acetyllysine1555 def: "Protein SMCA2_HUMAN with the residue 1555 substituted with N6-acetyllysine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070629 name: SMCA2_HUMAN-Phosphoserine1572 def: "Protein SMCA2_HUMAN with the residue 1572 substituted with Phosphoserine" [UniProtKB:P51531] xref: UniProtKB:P51531 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:B0070630 name: SMCA4_HUMAN-Phosphoserine613 def: "Protein SMCA4_HUMAN with the residue 613 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006791 ! protein N-terminus binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000119 ! heterochromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070631 name: SMCA4_HUMAN-Phosphoserine1570 def: "Protein SMCA4_HUMAN with the residue 1570 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070632 name: SMCA4_HUMAN-Phosphoserine1575 def: "Protein SMCA4_HUMAN with the residue 1575 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070633 name: SMCA4_HUMAN-Phosphoserine1586 def: "Protein SMCA4_HUMAN with the residue 1586 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070634 name: SMCA4_HUMAN-Phosphoserine1627 def: "Protein SMCA4_HUMAN with the residue 1627 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070635 name: SMCA4_HUMAN-Phosphoserine1631 def: "Protein SMCA4_HUMAN with the residue 1631 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070636 name: SMCA4_HUMAN-Phosphoserine1640 def: "Protein SMCA4_HUMAN with the residue 1640 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070637 name: SMCA4_HUMAN-Phosphoserine1642 def: "Protein SMCA4_HUMAN with the residue 1642 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070638 name: SMCA4_HUMAN-Phosphoserine1644 def: "Protein SMCA4_HUMAN with the residue 1644 substituted with Phosphoserine" [UniProtKB:P51532] xref: UniProtKB:P51532 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:B0070639 name: SMCA5_HUMAN-Phosphoserine66 def: "Protein SMCA5_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:O60264] xref: UniProtKB:O60264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054538 ! SMCA5_HUMAN [Term] id: CCO:B0070640 name: SMCA5_HUMAN-Phosphothreonine113 def: "Protein SMCA5_HUMAN with the residue 113 substituted with Phosphothreonine" [UniProtKB:O60264] xref: UniProtKB:O60264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054538 ! SMCA5_HUMAN [Term] id: CCO:B0070641 name: SMCA5_HUMAN-Phosphoserine116 def: "Protein SMCA5_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:O60264] xref: UniProtKB:O60264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054538 ! SMCA5_HUMAN [Term] id: CCO:B0070642 name: SMCA5_HUMAN-Phosphoserine137 def: "Protein SMCA5_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:O60264] xref: UniProtKB:O60264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054538 ! SMCA5_HUMAN [Term] id: CCO:B0070643 name: SMCA5_HUMAN-Phosphoserine755 def: "Protein SMCA5_HUMAN with the residue 755 substituted with Phosphoserine" [UniProtKB:O60264] xref: UniProtKB:O60264 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003445 ! ATPase activity relationship: has_function CCO:F0004675 ! nucleosome binding relationship: has_function CCO:F0005669 ! histone binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000806 ! chromatin remodeling complex relationship: located_in CCO:C0001147 ! RSF complex relationship: transformation_of CCO:B0054538 ! SMCA5_HUMAN [Term] id: CCO:B0070644 name: SMD2_HUMAN-N-acetylserine2 def: "Protein SMD2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P62316] xref: UniProtKB:P62316 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: transformation_of CCO:B0018244 ! SMD2_HUMAN [Term] id: CCO:B0070645 name: SMG7_HUMAN-Phosphoserine781 def: "Protein SMG7_HUMAN with the residue 781 substituted with Phosphoserine" [UniProtKB:Q92540] xref: UniProtKB:Q92540 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008162 ! protein phosphatase 2A binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058061 ! SMG7_HUMAN [Term] id: CCO:B0070646 name: SMG7_HUMAN-Phosphoserine897 def: "Protein SMG7_HUMAN with the residue 897 substituted with Phosphoserine" [UniProtKB:Q92540] xref: UniProtKB:Q92540 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058061 ! SMG7_HUMAN [Term] id: CCO:B0070647 name: SMN_HUMAN-Phosphothreonine25 def: "Protein SMN_HUMAN with the residue 25 substituted with Phosphothreonine" [UniProtKB:Q16637] xref: UniProtKB:Q16637 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000750 ! Cajal body relationship: transformation_of CCO:B0006110 ! SMN_HUMAN [Term] id: CCO:B0070648 name: SMRC1_HUMAN-Phosphoserine573 def: "Protein SMRC1_HUMAN with the residue 573 substituted with Phosphoserine" [UniProtKB:Q92922] xref: UniProtKB:Q92922 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005418 ! SMRC1_HUMAN [Term] id: CCO:B0070649 name: SMRC2_HUMAN-Phosphoserine286 def: "Protein SMRC2_HUMAN with the residue 286 substituted with Phosphoserine" [UniProtKB:Q8TAQ2] xref: UniProtKB:Q8TAQ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:B0070650 name: SMRCD_HUMAN-Phosphoserine34 def: "Protein SMRCD_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070651 name: SMRCD_HUMAN-Phosphoserine37 def: "Protein SMRCD_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070652 name: SMRCD_HUMAN-Phosphoserine39 def: "Protein SMRCD_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070653 name: SMRCD_HUMAN-Phosphothreonine54 def: "Protein SMRCD_HUMAN with the residue 54 substituted with Phosphothreonine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070654 name: SMRCD_HUMAN-Phosphoserine57 def: "Protein SMRCD_HUMAN with the residue 57 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070655 name: SMRCD_HUMAN-Phosphoserine67 def: "Protein SMRCD_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070656 name: SMRCD_HUMAN-Phosphoserine79 def: "Protein SMRCD_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070657 name: SMRCD_HUMAN-Phosphoserine95 def: "Protein SMRCD_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070658 name: SMRCD_HUMAN-Phosphoserine96 def: "Protein SMRCD_HUMAN with the residue 96 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070659 name: SMRCD_HUMAN-Phosphoserine98 def: "Protein SMRCD_HUMAN with the residue 98 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070660 name: SMRCD_HUMAN-Phosphoserine103 def: "Protein SMRCD_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070661 name: SMRCD_HUMAN-Phosphoserine124 def: "Protein SMRCD_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070662 name: SMRCD_HUMAN-Phosphoserine127 def: "Protein SMRCD_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070663 name: SMRCD_HUMAN-Phosphoserine132 def: "Protein SMRCD_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070664 name: SMRCD_HUMAN-Phosphoserine146 def: "Protein SMRCD_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070665 name: SMRCD_HUMAN-Phosphoserine152 def: "Protein SMRCD_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070666 name: SMRCD_HUMAN-Phosphoserine211 def: "Protein SMRCD_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070667 name: SMRCD_HUMAN-Phosphoserine212 def: "Protein SMRCD_HUMAN with the residue 212 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070668 name: SMRCD_HUMAN-Phosphoserine213 def: "Protein SMRCD_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070669 name: SMRCD_HUMAN-Phosphoserine214 def: "Protein SMRCD_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070670 name: SMRCD_HUMAN-Phosphoserine239 def: "Protein SMRCD_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070671 name: SMRCD_HUMAN-Phosphoserine242 def: "Protein SMRCD_HUMAN with the residue 242 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070672 name: SMRCD_HUMAN-Phosphoserine302 def: "Protein SMRCD_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:Q9H4L7] xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070673 name: SMRCD_HUMAN-Phosphoserine408 def: "Protein SMRCD_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:Q9H4L7] comment: By similarity xref: UniProtKB:Q9H4L7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:B0070674 name: SMRD3_HUMAN-Phosphoserine178 def: "Protein SMRD3_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q6STE5] xref: UniProtKB:Q6STE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056941 ! SMRD3_HUMAN [Term] id: CCO:B0070675 name: SMU1_HUMAN-N-acetylserine2 def: "Protein SMU1_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q2TAY7] xref: UniProtKB:Q2TAY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005691 ! SMU1_HUMAN [Term] id: CCO:B0070676 name: SNAG_HUMAN-Phosphoserine284 def: "Protein SNAG_HUMAN with the residue 284 substituted with Phosphoserine" [UniProtKB:Q99747] comment: By similarity xref: UniProtKB:Q99747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000325 ! mitochondrion relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0058452 ! SNAG_HUMAN [Term] id: CCO:B0070677 name: SNAG_HUMAN-Phosphotyrosine307 def: "Protein SNAG_HUMAN with the residue 307 substituted with Phosphotyrosine" [UniProtKB:Q99747] xref: UniProtKB:Q99747 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058452 ! SNAG_HUMAN [Term] id: CCO:B0070678 name: SNCAP_HUMAN-Phosphothreonine387 def: "Protein SNCAP_HUMAN with the residue 387 substituted with Phosphothreonine" [UniProtKB:Q9Y6H5] xref: UniProtKB:Q9Y6H5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001695 ! presynaptic membrane relationship: located_in CCO:C0001709 ! cell soma relationship: transformation_of CCO:B0006235 ! SNCAP_HUMAN [Term] id: CCO:B0070679 name: SND1_HUMAN-Phosphotyrosine109 def: "Protein SND1_HUMAN with the residue 109 substituted with Phosphotyrosine" [UniProtKB:Q7KZF4] xref: UniProtKB:Q7KZF4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057111 ! SND1_HUMAN [Term] id: CCO:B0070680 name: SND1_HUMAN-Phosphothreonine429 def: "Protein SND1_HUMAN with the residue 429 substituted with Phosphothreonine" [UniProtKB:Q7KZF4] xref: UniProtKB:Q7KZF4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003360 ! hydrolase activity, acting on ester bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000786 ! RNA-induced silencing complex relationship: located_in CCO:C0001642 ! melanosome relationship: transformation_of CCO:B0057111 ! SND1_HUMAN [Term] id: CCO:B0070681 name: SND1_HUMAN-Phosphoserine781 def: "Protein SND1_HUMAN with the residue 781 substituted with Phosphoserine" [UniProtKB:Q7KZF4] xref: UniProtKB:Q7KZF4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057111 ! SND1_HUMAN [Term] id: CCO:B0070682 name: SND1_HUMAN-Phosphotyrosine908 def: "Protein SND1_HUMAN with the residue 908 substituted with Phosphotyrosine" [UniProtKB:Q7KZF4] xref: UniProtKB:Q7KZF4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057111 ! SND1_HUMAN [Term] id: CCO:B0070683 name: SNIP1_HUMAN-Phosphoserine49 def: "Protein SNIP1_HUMAN with the residue 49 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0070684 name: SNIP1_HUMAN-Phosphoserine52 def: "Protein SNIP1_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0070685 name: SNIP1_HUMAN-Phosphoserine54 def: "Protein SNIP1_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q8TAD8] xref: UniProtKB:Q8TAD8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:B0070686 name: SNP23_HUMAN-N-acetylmethionine1 def: "Protein SNP23_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:O00161] xref: UniProtKB:O00161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062858 ! SNP23_HUMAN [Term] id: CCO:B0070687 name: SNP23_HUMAN-Phosphoserine110 def: "Protein SNP23_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:O00161] xref: UniProtKB:O00161 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062858 ! SNP23_HUMAN [Term] id: CCO:B0070688 name: SNP25_HUMAN-Phosphothreonine138 def: "Protein SNP25_HUMAN with the residue 138 substituted with Phosphothreonine" [UniProtKB:P60880] comment: By similarity xref: UniProtKB:P60880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055598 ! SNP25_HUMAN [Term] id: CCO:B0070689 name: SNP25_HUMAN-Phosphoserine187 def: "Protein SNP25_HUMAN with the residue 187 substituted with Phosphoserine" [UniProtKB:P60880] comment: By similarity xref: UniProtKB:P60880 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000880 ! synaptosome relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001141 ! SNARE complex relationship: located_in CCO:C0001707 ! neuron projection relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0055598 ! SNP25_HUMAN [Term] id: CCO:B0070690 name: SNPC1_HUMAN-Phosphoserine289 def: "Protein SNPC1_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:Q16533] xref: UniProtKB:Q16533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056144 ! SNPC1_HUMAN [Term] id: CCO:B0070691 name: SNPC1_HUMAN-Phosphoserine290 def: "Protein SNPC1_HUMAN with the residue 290 substituted with Phosphoserine" [UniProtKB:Q16533] xref: UniProtKB:Q16533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056144 ! SNPC1_HUMAN [Term] id: CCO:B0070692 name: SNPC1_HUMAN-Phosphoserine292 def: "Protein SNPC1_HUMAN with the residue 292 substituted with Phosphoserine" [UniProtKB:Q16533] xref: UniProtKB:Q16533 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056144 ! SNPC1_HUMAN [Term] id: CCO:B0070693 name: SNPC3_HUMAN-Phosphoserine74 def: "Protein SNPC3_HUMAN with the residue 74 substituted with Phosphoserine" [UniProtKB:Q92966] xref: UniProtKB:Q92966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058116 ! SNPC3_HUMAN [Term] id: CCO:B0070694 name: SNPC4_HUMAN-Phosphothreonine1157 def: "Protein SNPC4_HUMAN with the residue 1157 substituted with Phosphothreonine" [UniProtKB:Q5SXM2] xref: UniProtKB:Q5SXM2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000878 ! snRNA-activating protein complex relationship: transformation_of CCO:B0056550 ! SNPC4_HUMAN [Term] id: CCO:B0070695 name: SNPC4_HUMAN-Phosphoserine1224 def: "Protein SNPC4_HUMAN with the residue 1224 substituted with Phosphoserine" [UniProtKB:Q5SXM2] xref: UniProtKB:Q5SXM2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056550 ! SNPC4_HUMAN [Term] id: CCO:B0070696 name: SNRPA_HUMAN-N-acetylalanine2 def: "Protein SNRPA_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P09012] xref: UniProtKB:P09012 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063003 ! SNRPA_HUMAN [Term] id: CCO:B0070697 name: SNTA1_HUMAN-Phosphoserine189 def: "Protein SNTA1_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q13424] xref: UniProtKB:Q13424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0063265 ! SNTA1_HUMAN [Term] id: CCO:B0070698 name: SNTA1_HUMAN-Phosphoserine193 def: "Protein SNTA1_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:Q13424] xref: UniProtKB:Q13424 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063265 ! SNTA1_HUMAN [Term] id: CCO:B0070699 name: SNTB1_HUMAN-N-acetylalanine2 def: "Protein SNTB1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q13884] xref: UniProtKB:Q13884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:B0070700 name: SNTB1_HUMAN-Phosphoserine87 def: "Protein SNTB1_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q13884] xref: UniProtKB:Q13884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:B0070701 name: SNTB1_HUMAN-Phosphothreonine214 def: "Protein SNTB1_HUMAN with the residue 214 substituted with Phosphothreonine" [UniProtKB:Q13884] comment: By similarity xref: UniProtKB:Q13884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:B0070702 name: SNTB1_HUMAN-Phosphoserine219 def: "Protein SNTB1_HUMAN with the residue 219 substituted with Phosphoserine" [UniProtKB:Q13884] xref: UniProtKB:Q13884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:B0070703 name: SNTB1_HUMAN-Phosphoserine236 def: "Protein SNTB1_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:Q13884] comment: By similarity xref: UniProtKB:Q13884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:B0070704 name: SNTB1_HUMAN-Phosphoserine389 def: "Protein SNTB1_HUMAN with the residue 389 substituted with Phosphoserine" [UniProtKB:Q13884] xref: UniProtKB:Q13884 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000761 ! dystrophin-associated glycoprotein complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:B0070705 name: SNTB2_HUMAN-Phosphoserine95 def: "Protein SNTB2_HUMAN with the residue 95 substituted with Phosphoserine" [UniProtKB:Q13425] xref: UniProtKB:Q13425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063299 ! SNTB2_HUMAN [Term] id: CCO:B0070706 name: SNTB2_HUMAN-Phosphoserine110 def: "Protein SNTB2_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:Q13425] xref: UniProtKB:Q13425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063299 ! SNTB2_HUMAN [Term] id: CCO:B0070707 name: SNTB2_HUMAN-Phosphothreonine201 def: "Protein SNTB2_HUMAN with the residue 201 substituted with Phosphothreonine" [UniProtKB:Q13425] xref: UniProtKB:Q13425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000761 ! dystrophin-associated glycoprotein complex relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0063299 ! SNTB2_HUMAN [Term] id: CCO:B0070708 name: SNTB2_HUMAN-Phosphoserine222 def: "Protein SNTB2_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q13425] xref: UniProtKB:Q13425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063299 ! SNTB2_HUMAN [Term] id: CCO:B0070709 name: SNTB2_HUMAN-Phosphoserine233 def: "Protein SNTB2_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:Q13425] xref: UniProtKB:Q13425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063299 ! SNTB2_HUMAN [Term] id: CCO:B0070710 name: SNTB2_HUMAN-Phosphoserine393 def: "Protein SNTB2_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:Q13425] xref: UniProtKB:Q13425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063299 ! SNTB2_HUMAN [Term] id: CCO:B0070711 name: SNX13_HUMAN-Phosphothreonine359 def: "Protein SNX13_HUMAN with the residue 359 substituted with Phosphothreonine" [UniProtKB:Q9Y5W8] xref: UniProtKB:Q9Y5W8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059390 ! SNX13_HUMAN [Term] id: CCO:B0070712 name: SNX17_HUMAN-Phosphothreonine334 def: "Protein SNX17_HUMAN with the residue 334 substituted with Phosphothreonine" [UniProtKB:Q15036] comment: By similarity xref: UniProtKB:Q15036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056037 ! SNX17_HUMAN [Term] id: CCO:B0070713 name: SNX17_HUMAN-Phosphoserine409 def: "Protein SNX17_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q15036] xref: UniProtKB:Q15036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056037 ! SNX17_HUMAN [Term] id: CCO:B0070714 name: SNX17_HUMAN-Phosphoserine415 def: "Protein SNX17_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q15036] xref: UniProtKB:Q15036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056037 ! SNX17_HUMAN [Term] id: CCO:B0070715 name: SNX17_HUMAN-Phosphoserine421 def: "Protein SNX17_HUMAN with the residue 421 substituted with Phosphoserine" [UniProtKB:Q15036] xref: UniProtKB:Q15036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056037 ! SNX17_HUMAN [Term] id: CCO:B0070716 name: SNX17_HUMAN-Phosphoserine437 def: "Protein SNX17_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q15036] xref: UniProtKB:Q15036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_function CCO:F0008008 ! low-density lipoprotein receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0056037 ! SNX17_HUMAN [Term] id: CCO:B0070717 name: SNX17_HUMAN-Phosphoserine440 def: "Protein SNX17_HUMAN with the residue 440 substituted with Phosphoserine" [UniProtKB:Q15036] xref: UniProtKB:Q15036 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056037 ! SNX17_HUMAN [Term] id: CCO:B0070718 name: SOCS6_HUMAN-Phosphoserine419 def: "Protein SOCS6_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:O14544] xref: UniProtKB:O14544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054349 ! SOCS6_HUMAN [Term] id: CCO:B0070719 name: SODM_HUMAN-Nitrated tyrosine58 def: "Protein SODM_HUMAN with the residue 58 substituted with Nitrated tyrosine" [UniProtKB:P04179] xref: UniProtKB:P04179 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0033778 ! SODM_HUMAN [Term] id: CCO:B0070720 name: SOLO_HUMAN-Phosphoserine931 def: "Protein SOLO_HUMAN with the residue 931 substituted with Phosphoserine" [UniProtKB:Q8TER5] xref: UniProtKB:Q8TER5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0057955 ! SOLO_HUMAN [Term] id: CCO:B0070721 name: SOMA_HUMAN-Phosphoserine132 def: "Protein SOMA_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:P01241] xref: UniProtKB:P01241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054843 ! SOMA_HUMAN [Term] id: CCO:B0070722 name: SOMA_HUMAN-glutamine163 def: "Protein SOMA_HUMAN with the residue 163 substituted with glutamine" [UniProtKB:P01241] comment: by deterioration; xref: UniProtKB:P01241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054843 ! SOMA_HUMAN [Term] id: CCO:B0070723 name: SOMA_HUMAN-Phosphoserine176 def: "Protein SOMA_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:P01241] xref: UniProtKB:P01241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001433 ! growth hormone receptor binding relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0054843 ! SOMA_HUMAN [Term] id: CCO:B0070724 name: SOMA_HUMAN-asparagine178 def: "Protein SOMA_HUMAN with the residue 178 substituted with asparagine" [UniProtKB:P01241] comment: by deterioration; xref: UniProtKB:P01241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054843 ! SOMA_HUMAN [Term] id: CCO:B0070725 name: SON_HUMAN-Phosphoserine94 def: "Protein SON_HUMAN with the residue 94 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070726 name: SON_HUMAN-Phosphoserine154 def: "Protein SON_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070727 name: SON_HUMAN-Phosphoserine283 def: "Protein SON_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070728 name: SON_HUMAN-Phosphoserine910 def: "Protein SON_HUMAN with the residue 910 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070729 name: SON_HUMAN-Phosphoserine1651 def: "Protein SON_HUMAN with the residue 1651 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070730 name: SON_HUMAN-Phosphoserine1688 def: "Protein SON_HUMAN with the residue 1688 substituted with Phosphoserine" [UniProtKB:P18583] comment: By similarity xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070731 name: SON_HUMAN-Phosphoserine1697 def: "Protein SON_HUMAN with the residue 1697 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070732 name: SON_HUMAN-Phosphoserine1766 def: "Protein SON_HUMAN with the residue 1766 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070733 name: SON_HUMAN-Phosphoserine1769 def: "Protein SON_HUMAN with the residue 1769 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070734 name: SON_HUMAN-Phosphoserine1784 def: "Protein SON_HUMAN with the residue 1784 substituted with Phosphoserine" [UniProtKB:P18583] comment: By similarity xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070735 name: SON_HUMAN-Phosphoserine1948 def: "Protein SON_HUMAN with the residue 1948 substituted with Phosphoserine" [UniProtKB:P18583] comment: By similarity xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070736 name: SON_HUMAN-Phosphoserine1950 def: "Protein SON_HUMAN with the residue 1950 substituted with Phosphoserine" [UniProtKB:P18583] comment: By similarity xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070737 name: SON_HUMAN-Phosphoserine1961 def: "Protein SON_HUMAN with the residue 1961 substituted with Phosphoserine" [UniProtKB:P18583] comment: By similarity xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070738 name: SON_HUMAN-Phosphoserine2009 def: "Protein SON_HUMAN with the residue 2009 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070739 name: SON_HUMAN-Phosphoserine2011 def: "Protein SON_HUMAN with the residue 2011 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070740 name: SON_HUMAN-Phosphoserine2013 def: "Protein SON_HUMAN with the residue 2013 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070741 name: SON_HUMAN-Phosphoserine2029 def: "Protein SON_HUMAN with the residue 2029 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070742 name: SON_HUMAN-Phosphoserine2031 def: "Protein SON_HUMAN with the residue 2031 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070743 name: SON_HUMAN-N6-acetyllysine2055 def: "Protein SON_HUMAN with the residue 2055 substituted with N6-acetyllysine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070744 name: SON_HUMAN-Phosphoserine2129 def: "Protein SON_HUMAN with the residue 2129 substituted with Phosphoserine" [UniProtKB:P18583] xref: UniProtKB:P18583 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055101 ! SON_HUMAN [Term] id: CCO:B0070745 name: SORT_HUMAN-Phosphoserine825 def: "Protein SORT_HUMAN with the residue 825 substituted with Phosphoserine" [UniProtKB:Q99523] xref: UniProtKB:Q99523 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058421 ! SORT_HUMAN [Term] id: CCO:B0070746 name: SOS1_HUMAN-Phosphoserine1134 def: "Protein SOS1_HUMAN with the residue 1134 substituted with Phosphoserine" [UniProtKB:Q07889] xref: UniProtKB:Q07889 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:B0070747 name: SOS1_HUMAN-Phosphoserine1137 def: "Protein SOS1_HUMAN with the residue 1137 substituted with Phosphoserine" [UniProtKB:Q07889] xref: UniProtKB:Q07889 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:B0070748 name: SOX11_HUMAN-Phosphoserine206 def: "Protein SOX11_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:P35716] xref: UniProtKB:P35716 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020254 ! SOX11_HUMAN [Term] id: CCO:B0070749 name: SOX13_HUMAN-Phosphoserine317 def: "Protein SOX13_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q9UN79] xref: UniProtKB:Q9UN79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059247 ! SOX13_HUMAN [Term] id: CCO:B0070750 name: SOX13_HUMAN-Phosphoserine364 def: "Protein SOX13_HUMAN with the residue 364 substituted with Phosphoserine" [UniProtKB:Q9UN79] xref: UniProtKB:Q9UN79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059247 ! SOX13_HUMAN [Term] id: CCO:B0070751 name: SOX13_HUMAN-Phosphoserine368 def: "Protein SOX13_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q9UN79] xref: UniProtKB:Q9UN79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059247 ! SOX13_HUMAN [Term] id: CCO:B0070752 name: SOX5_HUMAN-Phosphothreonine108 def: "Protein SOX5_HUMAN with the residue 108 substituted with Phosphothreonine" [UniProtKB:P35711] comment: By similarity xref: UniProtKB:P35711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055300 ! SOX5_HUMAN [Term] id: CCO:B0070753 name: SOX5_HUMAN-Phosphoserine414 def: "Protein SOX5_HUMAN with the residue 414 substituted with Phosphoserine" [UniProtKB:P35711] comment: By similarity xref: UniProtKB:P35711 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055300 ! SOX5_HUMAN [Term] id: CCO:B0070754 name: SP100_HUMAN-Phosphoserine18 def: "Protein SP100_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070755 name: SP100_HUMAN-Phosphoserine157 def: "Protein SP100_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070756 name: SP100_HUMAN-Phosphoserine327 def: "Protein SP100_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070757 name: SP100_HUMAN-Phosphoserine328 def: "Protein SP100_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070758 name: SP100_HUMAN-Phosphoserine331 def: "Protein SP100_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070759 name: SP100_HUMAN-Phosphoserine334 def: "Protein SP100_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070760 name: SP100_HUMAN-Phosphothreonine335 def: "Protein SP100_HUMAN with the residue 335 substituted with Phosphothreonine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070761 name: SP100_HUMAN-Phosphoserine407 def: "Protein SP100_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070762 name: SP100_HUMAN-Phosphoserine409 def: "Protein SP100_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070763 name: SP100_HUMAN-Phosphoserine410 def: "Protein SP100_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070764 name: SP100_HUMAN-Phosphoserine451 def: "Protein SP100_HUMAN with the residue 451 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070765 name: SP100_HUMAN-Phosphoserine452 def: "Protein SP100_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070766 name: SP100_HUMAN-Phosphoserine453 def: "Protein SP100_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070767 name: SP100_HUMAN-Phosphoserine456 def: "Protein SP100_HUMAN with the residue 456 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070768 name: SP100_HUMAN-Phosphoserine459 def: "Protein SP100_HUMAN with the residue 459 substituted with Phosphoserine" [UniProtKB:P23497] xref: UniProtKB:P23497 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004213 ! protein domain specific binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:B0070769 name: SP130_HUMAN-Phosphothreonine355 def: "Protein SP130_HUMAN with the residue 355 substituted with Phosphothreonine" [UniProtKB:Q9H0E3] xref: UniProtKB:Q9H0E3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058650 ! SP130_HUMAN [Term] id: CCO:B0070770 name: SP130_HUMAN-Phosphoserine442 def: "Protein SP130_HUMAN with the residue 442 substituted with Phosphoserine" [UniProtKB:Q9H0E3] xref: UniProtKB:Q9H0E3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058650 ! SP130_HUMAN [Term] id: CCO:B0070771 name: SP130_HUMAN-Phosphoserine454 def: "Protein SP130_HUMAN with the residue 454 substituted with Phosphoserine" [UniProtKB:Q9H0E3] xref: UniProtKB:Q9H0E3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058650 ! SP130_HUMAN [Term] id: CCO:B0070772 name: SP130_HUMAN-Phosphoserine455 def: "Protein SP130_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q9H0E3] xref: UniProtKB:Q9H0E3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058650 ! SP130_HUMAN [Term] id: CCO:B0070773 name: SP130_HUMAN-Phosphoserine875 def: "Protein SP130_HUMAN with the residue 875 substituted with Phosphoserine" [UniProtKB:Q9H0E3] xref: UniProtKB:Q9H0E3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058650 ! SP130_HUMAN [Term] id: CCO:B0070774 name: SP16H_HUMAN-Phosphoserine508 def: "Protein SP16H_HUMAN with the residue 508 substituted with Phosphoserine" [UniProtKB:Q9Y5B9] xref: UniProtKB:Q9Y5B9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032537 ! SP16H_HUMAN [Term] id: CCO:B0070775 name: SP16H_HUMAN-Phosphoserine650 def: "Protein SP16H_HUMAN with the residue 650 substituted with Phosphoserine" [UniProtKB:Q9Y5B9] xref: UniProtKB:Q9Y5B9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032537 ! SP16H_HUMAN [Term] id: CCO:B0070776 name: SP16H_HUMAN-Phosphoserine1015 def: "Protein SP16H_HUMAN with the residue 1015 substituted with Phosphoserine" [UniProtKB:Q9Y5B9] xref: UniProtKB:Q9Y5B9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032537 ! SP16H_HUMAN [Term] id: CCO:B0070777 name: SP2_HUMAN-Phosphothreonine550 def: "Protein SP2_HUMAN with the residue 550 substituted with Phosphothreonine" [UniProtKB:Q02086] xref: UniProtKB:Q02086 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055704 ! SP2_HUMAN [Term] id: CCO:B0070778 name: SP30L_HUMAN-Phosphothreonine92 def: "Protein SP30L_HUMAN with the residue 92 substituted with Phosphothreonine" [UniProtKB:Q9HAJ7] xref: UniProtKB:Q9HAJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058763 ! SP30L_HUMAN [Term] id: CCO:B0070779 name: SP30L_HUMAN-Phosphoserine93 def: "Protein SP30L_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q9HAJ7] comment: By similarity xref: UniProtKB:Q9HAJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058763 ! SP30L_HUMAN [Term] id: CCO:B0070780 name: SP30L_HUMAN-Phosphoserine99 def: "Protein SP30L_HUMAN with the residue 99 substituted with Phosphoserine" [UniProtKB:Q9HAJ7] xref: UniProtKB:Q9HAJ7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058763 ! SP30L_HUMAN [Term] id: CCO:B0070781 name: SP3_HUMAN-Phosphoserine73 def: "Protein SP3_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:Q02447] xref: UniProtKB:Q02447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055710 ! SP3_HUMAN [Term] id: CCO:B0070782 name: SP3_HUMAN-Phosphoserine563 def: "Protein SP3_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:Q02447] xref: UniProtKB:Q02447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055710 ! SP3_HUMAN [Term] id: CCO:B0070783 name: SP3_HUMAN-Phosphoserine566 def: "Protein SP3_HUMAN with the residue 566 substituted with Phosphoserine" [UniProtKB:Q02447] xref: UniProtKB:Q02447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055710 ! SP3_HUMAN [Term] id: CCO:B0070784 name: SP3_HUMAN-Phosphoserine646 def: "Protein SP3_HUMAN with the residue 646 substituted with Phosphoserine" [UniProtKB:Q02447] xref: UniProtKB:Q02447 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055710 ! SP3_HUMAN [Term] id: CCO:B0070785 name: SP4_HUMAN-Phosphoserine691 def: "Protein SP4_HUMAN with the residue 691 substituted with Phosphoserine" [UniProtKB:Q02446] xref: UniProtKB:Q02446 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055709 ! SP4_HUMAN [Term] id: CCO:B0070786 name: SPAG5_HUMAN-Phosphoserine43 def: "Protein SPAG5_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0070787 name: SPAG5_HUMAN-Phosphothreonine50 def: "Protein SPAG5_HUMAN with the residue 50 substituted with Phosphothreonine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0070788 name: SPAG5_HUMAN-Phosphoserine65 def: "Protein SPAG5_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q96R06] xref: UniProtKB:Q96R06 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002058 ! SPAG5_HUMAN [Term] id: CCO:B0070789 name: SPAT2_HUMAN-Phosphoserine253 def: "Protein SPAT2_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:Q9UM82] xref: UniProtKB:Q9UM82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062808 ! SPAT2_HUMAN [Term] id: CCO:B0070790 name: SPB4_HUMAN-N-acetylmethionine1 def: "Protein SPB4_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P48594] xref: UniProtKB:P48594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001222 ! endopeptidase inhibitor activity relationship: has_function CCO:F0001223 ! serine-type endopeptidase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055408 ! SPB4_HUMAN [Term] id: CCO:B0070791 name: SPEG_HUMAN-Phosphoserine313 def: "Protein SPEG_HUMAN with the residue 313 substituted with Phosphoserine" [UniProtKB:Q15772] comment: By similarity xref: UniProtKB:Q15772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056109 ! SPEG_HUMAN [Term] id: CCO:B0070792 name: SPEG_HUMAN-Phosphothreonine449 def: "Protein SPEG_HUMAN with the residue 449 substituted with Phosphothreonine" [UniProtKB:Q15772] xref: UniProtKB:Q15772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056109 ! SPEG_HUMAN [Term] id: CCO:B0070793 name: SPEG_HUMAN-Phosphoserine453 def: "Protein SPEG_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q15772] xref: UniProtKB:Q15772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056109 ! SPEG_HUMAN [Term] id: CCO:B0070794 name: SPEG_HUMAN-Phosphoserine476 def: "Protein SPEG_HUMAN with the residue 476 substituted with Phosphoserine" [UniProtKB:Q15772] comment: By similarity xref: UniProtKB:Q15772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056109 ! SPEG_HUMAN [Term] id: CCO:B0070795 name: SPEG_HUMAN-Phosphothreonine599 def: "Protein SPEG_HUMAN with the residue 599 substituted with Phosphothreonine" [UniProtKB:Q15772] xref: UniProtKB:Q15772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056109 ! SPEG_HUMAN [Term] id: CCO:B0070796 name: SPEG_HUMAN-Phosphoserine1172 def: "Protein SPEG_HUMAN with the residue 1172 substituted with Phosphoserine" [UniProtKB:Q15772] comment: By similarity xref: UniProtKB:Q15772 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056109 ! SPEG_HUMAN [Term] id: CCO:B0070797 name: SPF30_HUMAN-Phosphoserine201 def: "Protein SPF30_HUMAN with the residue 201 substituted with Phosphoserine" [UniProtKB:O75940] xref: UniProtKB:O75940 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0054679 ! SPF30_HUMAN [Term] id: CCO:B0070798 name: SPHK1_HUMAN-Phosphothreonine193 def: "Protein SPHK1_HUMAN with the residue 193 substituted with Phosphothreonine" [UniProtKB:Q9NYA1] xref: UniProtKB:Q9NYA1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000614 ! diacylglycerol kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001942 ! sphinganine kinase activity relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003533 ! D-erythro-sphingosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0002176 ! SPHK1_HUMAN [Term] id: CCO:B0070799 name: SPIN1_HUMAN-Phosphoserine124 def: "Protein SPIN1_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q9Y657] xref: UniProtKB:Q9Y657 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002262 ! SPIN1_HUMAN [Term] id: CCO:B0070800 name: SPIN1_HUMAN-Phosphoserine199 def: "Protein SPIN1_HUMAN with the residue 199 substituted with Phosphoserine" [UniProtKB:Q9Y657] xref: UniProtKB:Q9Y657 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002262 ! SPIN1_HUMAN [Term] id: CCO:B0070801 name: SPN90_HUMAN-Phosphothreonine181 def: "Protein SPN90_HUMAN with the residue 181 substituted with Phosphothreonine" [UniProtKB:Q9NZQ3] xref: UniProtKB:Q9NZQ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000440 ! intermediate filament relationship: transformation_of CCO:B0059010 ! SPN90_HUMAN [Term] id: CCO:B0070802 name: SPRE2_HUMAN-Phosphotyrosine228 def: "Protein SPRE2_HUMAN with the residue 228 substituted with Phosphotyrosine" [UniProtKB:Q7Z698] comment: Probable xref: UniProtKB:Q7Z698 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057194 ! SPRE2_HUMAN [Term] id: CCO:B0070803 name: SPRE2_HUMAN-Phosphotyrosine231 def: "Protein SPRE2_HUMAN with the residue 231 substituted with Phosphotyrosine" [UniProtKB:Q7Z698] comment: Probable xref: UniProtKB:Q7Z698 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057194 ! SPRE2_HUMAN [Term] id: CCO:B0070804 name: SPT6H_HUMAN-Phosphoserine73 def: "Protein SPT6H_HUMAN with the residue 73 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070805 name: SPT6H_HUMAN-Phosphoserine75 def: "Protein SPT6H_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070806 name: SPT6H_HUMAN-Phosphoserine78 def: "Protein SPT6H_HUMAN with the residue 78 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070807 name: SPT6H_HUMAN-Phosphoserine125 def: "Protein SPT6H_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070808 name: SPT6H_HUMAN-Phosphoserine179 def: "Protein SPT6H_HUMAN with the residue 179 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070809 name: SPT6H_HUMAN-Phosphoserine267 def: "Protein SPT6H_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070810 name: SPT6H_HUMAN-Phosphothreonine1523 def: "Protein SPT6H_HUMAN with the residue 1523 substituted with Phosphothreonine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070811 name: SPT6H_HUMAN-Phosphoserine1526 def: "Protein SPT6H_HUMAN with the residue 1526 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070812 name: SPT6H_HUMAN-Phosphothreonine1532 def: "Protein SPT6H_HUMAN with the residue 1532 substituted with Phosphothreonine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070813 name: SPT6H_HUMAN-Phosphoserine1535 def: "Protein SPT6H_HUMAN with the residue 1535 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003360 ! hydrolase activity, acting on ester bonds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070814 name: SPT6H_HUMAN-Phosphothreonine1539 def: "Protein SPT6H_HUMAN with the residue 1539 substituted with Phosphothreonine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070815 name: SPT6H_HUMAN-Phosphoserine1701 def: "Protein SPT6H_HUMAN with the residue 1701 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070816 name: SPT6H_HUMAN-Phosphoserine1703 def: "Protein SPT6H_HUMAN with the residue 1703 substituted with Phosphoserine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070817 name: SPT6H_HUMAN-Phosphothreonine1718 def: "Protein SPT6H_HUMAN with the residue 1718 substituted with Phosphothreonine" [UniProtKB:Q7KZ85] xref: UniProtKB:Q7KZ85 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014838 ! SPT6H_HUMAN [Term] id: CCO:B0070818 name: SPTA2_HUMAN-Phosphoserine1029 def: "Protein SPTA2_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q13813] comment: By similarity xref: UniProtKB:Q13813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:B0070819 name: SPTA2_HUMAN-Phosphoserine1031 def: "Protein SPTA2_HUMAN with the residue 1031 substituted with Phosphoserine" [UniProtKB:Q13813] comment: By similarity xref: UniProtKB:Q13813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:B0070820 name: SPTA2_HUMAN-Phosphotyrosine1176 def: "Protein SPTA2_HUMAN with the residue 1176 substituted with Phosphotyrosine" [UniProtKB:Q13813] comment: By similarity xref: UniProtKB:Q13813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:B0070821 name: SPTA2_HUMAN-Phosphoserine1217 def: "Protein SPTA2_HUMAN with the residue 1217 substituted with Phosphoserine" [UniProtKB:Q13813] xref: UniProtKB:Q13813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000529 ! spectrin relationship: transformation_of CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:B0070822 name: SPTA2_HUMAN-Phosphoserine1323 def: "Protein SPTA2_HUMAN with the residue 1323 substituted with Phosphoserine" [UniProtKB:Q13813] xref: UniProtKB:Q13813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:B0070823 name: SPTA2_HUMAN-Phosphotyrosine2423 def: "Protein SPTA2_HUMAN with the residue 2423 substituted with Phosphotyrosine" [UniProtKB:Q13813] xref: UniProtKB:Q13813 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:B0070824 name: SPTB1_HUMAN-Phosphoserine36 def: "Protein SPTB1_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:P11277] comment: By similarity xref: UniProtKB:P11277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054990 ! SPTB1_HUMAN [Term] id: CCO:B0070825 name: SPTB1_HUMAN-Phosphothreonine2110 def: "Protein SPTB1_HUMAN with the residue 2110 substituted with Phosphothreonine" [UniProtKB:P11277] xref: UniProtKB:P11277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054990 ! SPTB1_HUMAN [Term] id: CCO:B0070826 name: SPTB1_HUMAN-Phosphoserine2114 def: "Protein SPTB1_HUMAN with the residue 2114 substituted with Phosphoserine" [UniProtKB:P11277] xref: UniProtKB:P11277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054990 ! SPTB1_HUMAN [Term] id: CCO:B0070827 name: SPTB1_HUMAN-Phosphoserine2117 def: "Protein SPTB1_HUMAN with the residue 2117 substituted with Phosphoserine" [UniProtKB:P11277] xref: UniProtKB:P11277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000529 ! spectrin relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0054990 ! SPTB1_HUMAN [Term] id: CCO:B0070828 name: SPTB1_HUMAN-Phosphoserine2123 def: "Protein SPTB1_HUMAN with the residue 2123 substituted with Phosphoserine" [UniProtKB:P11277] xref: UniProtKB:P11277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054990 ! SPTB1_HUMAN [Term] id: CCO:B0070829 name: SPTB1_HUMAN-Phosphoserine2125 def: "Protein SPTB1_HUMAN with the residue 2125 substituted with Phosphoserine" [UniProtKB:P11277] xref: UniProtKB:P11277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054990 ! SPTB1_HUMAN [Term] id: CCO:B0070830 name: SPTB1_HUMAN-Phosphoserine2128 def: "Protein SPTB1_HUMAN with the residue 2128 substituted with Phosphoserine" [UniProtKB:P11277] xref: UniProtKB:P11277 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054990 ! SPTB1_HUMAN [Term] id: CCO:B0070831 name: SPTB2_HUMAN-Phosphothreonine2159 def: "Protein SPTB2_HUMAN with the residue 2159 substituted with Phosphothreonine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0070832 name: SPTB2_HUMAN-Phosphoserine2160 def: "Protein SPTB2_HUMAN with the residue 2160 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0070833 name: SPTB2_HUMAN-Phosphothreonine2187 def: "Protein SPTB2_HUMAN with the residue 2187 substituted with Phosphothreonine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0070834 name: SPTB2_HUMAN-Phosphothreonine2328 def: "Protein SPTB2_HUMAN with the residue 2328 substituted with Phosphothreonine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0070835 name: SPTB2_HUMAN-Phosphoserine2341 def: "Protein SPTB2_HUMAN with the residue 2341 substituted with Phosphoserine" [UniProtKB:Q01082] xref: UniProtKB:Q01082 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:B0070836 name: SPTN2_HUMAN-Phosphoserine2171 def: "Protein SPTN2_HUMAN with the residue 2171 substituted with Phosphoserine" [UniProtKB:O15020] xref: UniProtKB:O15020 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054399 ! SPTN2_HUMAN [Term] id: CCO:B0070837 name: SPTN2_HUMAN-Phosphoserine2199 def: "Protein SPTN2_HUMAN with the residue 2199 substituted with Phosphoserine" [UniProtKB:O15020] comment: By similarity xref: UniProtKB:O15020 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054399 ! SPTN2_HUMAN [Term] id: CCO:B0070838 name: SPTN2_HUMAN-Phosphothreonine2354 def: "Protein SPTN2_HUMAN with the residue 2354 substituted with Phosphothreonine" [UniProtKB:O15020] comment: By similarity xref: UniProtKB:O15020 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000529 ! spectrin relationship: transformation_of CCO:B0054399 ! SPTN2_HUMAN [Term] id: CCO:B0070839 name: SPTN4_HUMAN-Phosphothreonine2111 def: "Protein SPTN4_HUMAN with the residue 2111 substituted with Phosphothreonine" [UniProtKB:Q9H254] xref: UniProtKB:Q9H254 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058677 ! SPTN4_HUMAN [Term] id: CCO:B0070840 name: SPTN4_HUMAN-Phosphothreonine2112 def: "Protein SPTN4_HUMAN with the residue 2112 substituted with Phosphothreonine" [UniProtKB:Q9H254] xref: UniProtKB:Q9H254 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004447 ! ankyrin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000529 ! spectrin relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0000818 ! PML body relationship: transformation_of CCO:B0058677 ! SPTN4_HUMAN [Term] id: CCO:B0070841 name: SPTN4_HUMAN-Phosphoserine2121 def: "Protein SPTN4_HUMAN with the residue 2121 substituted with Phosphoserine" [UniProtKB:Q9H254] xref: UniProtKB:Q9H254 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058677 ! SPTN4_HUMAN [Term] id: CCO:B0070842 name: SPY1_HUMAN-Phosphotyrosine53 def: "Protein SPY1_HUMAN with the residue 53 substituted with Phosphotyrosine" [UniProtKB:O43609] xref: UniProtKB:O43609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054499 ! SPY1_HUMAN [Term] id: CCO:B0070843 name: SPY4_HUMAN-Phosphoserine125 def: "Protein SPY4_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q9C004] xref: UniProtKB:Q9C004 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0058614 ! SPY4_HUMAN [Term] id: CCO:B0070844 name: SQSTM_HUMAN-Phosphoserine24 def: "Protein SQSTM_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:Q13501] comment: By similarity xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070845 name: SQSTM_HUMAN-Phosphotyrosine148 def: "Protein SQSTM_HUMAN with the residue 148 substituted with Phosphotyrosine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070846 name: SQSTM_HUMAN-Phosphoserine170 def: "Protein SQSTM_HUMAN with the residue 170 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004210 ! protein kinase binding relationship: has_function CCO:F0004611 ! receptor tyrosine kinase binding relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0005797 ! ubiquitin binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000353 ! late endosome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070847 name: SQSTM_HUMAN-Phosphoserine176 def: "Protein SQSTM_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070848 name: SQSTM_HUMAN-Phosphoserine207 def: "Protein SQSTM_HUMAN with the residue 207 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070849 name: SQSTM_HUMAN-Phosphothreonine269 def: "Protein SQSTM_HUMAN with the residue 269 substituted with Phosphothreonine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070850 name: SQSTM_HUMAN-Phosphoserine272 def: "Protein SQSTM_HUMAN with the residue 272 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070851 name: SQSTM_HUMAN-Phosphoserine276 def: "Protein SQSTM_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070852 name: SQSTM_HUMAN-Phosphoserine328 def: "Protein SQSTM_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070853 name: SQSTM_HUMAN-Phosphoserine332 def: "Protein SQSTM_HUMAN with the residue 332 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070854 name: SQSTM_HUMAN-Phosphoserine355 def: "Protein SQSTM_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070855 name: SQSTM_HUMAN-Phosphoserine361 def: "Protein SQSTM_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070856 name: SQSTM_HUMAN-Phosphoserine365 def: "Protein SQSTM_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070857 name: SQSTM_HUMAN-Phosphoserine366 def: "Protein SQSTM_HUMAN with the residue 366 substituted with Phosphoserine" [UniProtKB:Q13501] xref: UniProtKB:Q13501 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:B0070858 name: SR140_HUMAN-Phosphoserine811 def: "Protein SR140_HUMAN with the residue 811 substituted with Phosphoserine" [UniProtKB:O15042] xref: UniProtKB:O15042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063169 ! SR140_HUMAN [Term] id: CCO:B0070859 name: SR140_HUMAN-Phosphoserine946 def: "Protein SR140_HUMAN with the residue 946 substituted with Phosphoserine" [UniProtKB:O15042] xref: UniProtKB:O15042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063169 ! SR140_HUMAN [Term] id: CCO:B0070860 name: SR140_HUMAN-Phosphoserine948 def: "Protein SR140_HUMAN with the residue 948 substituted with Phosphoserine" [UniProtKB:O15042] xref: UniProtKB:O15042 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063169 ! SR140_HUMAN [Term] id: CCO:B0070861 name: SRA1_HUMAN-Phosphoserine60 def: "Protein SRA1_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q9HD15] xref: UniProtKB:Q9HD15 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058823 ! SRA1_HUMAN [Term] id: CCO:B0070862 name: SRA1_HUMAN-Phosphothreonine68 def: "Protein SRA1_HUMAN with the residue 68 substituted with Phosphothreonine" [UniProtKB:Q9HD15] xref: UniProtKB:Q9HD15 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: located_in CCO:C0001172 ! leading edge relationship: transformation_of CCO:B0058823 ! SRA1_HUMAN [Term] id: CCO:B0070863 name: SRBP1_HUMAN-Phosphoserine117 def: "Protein SRBP1_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:P36956] xref: UniProtKB:P36956 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049929 ! SRBP1_HUMAN [Term] id: CCO:B0070864 name: SRBS1_HUMAN-Phosphotyrosine79 def: "Protein SRBS1_HUMAN with the residue 79 substituted with Phosphotyrosine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0070865 name: SRBS1_HUMAN-Phosphoserine86 def: "Protein SRBS1_HUMAN with the residue 86 substituted with Phosphoserine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0070866 name: SRBS1_HUMAN-Phosphoserine472 def: "Protein SRBS1_HUMAN with the residue 472 substituted with Phosphoserine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0070867 name: SRBS1_HUMAN-Phosphoserine665 def: "Protein SRBS1_HUMAN with the residue 665 substituted with Phosphoserine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0070868 name: SRBS1_HUMAN-Phosphothreonine862 def: "Protein SRBS1_HUMAN with the residue 862 substituted with Phosphothreonine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001460 ! insulin receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001705 ! cytoskeletal protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000465 ! cell-cell adherens junction relationship: located_in CCO:C0000467 ! zonula adherens relationship: located_in CCO:C0000476 ! cell-substrate adherens junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0070869 name: SRBS1_HUMAN-Phosphoserine945 def: "Protein SRBS1_HUMAN with the residue 945 substituted with Phosphoserine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0070870 name: SRBS1_HUMAN-Phosphoserine953 def: "Protein SRBS1_HUMAN with the residue 953 substituted with Phosphoserine" [UniProtKB:Q9BX66] xref: UniProtKB:Q9BX66 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:B0070871 name: SRBS2_HUMAN-Phosphoserine30 def: "Protein SRBS2_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070872 name: SRBS2_HUMAN-Phosphoserine259 def: "Protein SRBS2_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:O94875] xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070873 name: SRBS2_HUMAN-Phosphothreonine277 def: "Protein SRBS2_HUMAN with the residue 277 substituted with Phosphothreonine" [UniProtKB:O94875] xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070874 name: SRBS2_HUMAN-Phosphoserine278 def: "Protein SRBS2_HUMAN with the residue 278 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070875 name: SRBS2_HUMAN-Phosphoserine298 def: "Protein SRBS2_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070876 name: SRBS2_HUMAN-Phosphoserine299 def: "Protein SRBS2_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070877 name: SRBS2_HUMAN-Phosphoserine301 def: "Protein SRBS2_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:O94875] xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070878 name: SRBS2_HUMAN-Phosphoserine302 def: "Protein SRBS2_HUMAN with the residue 302 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070879 name: SRBS2_HUMAN-Phosphothreonine371 def: "Protein SRBS2_HUMAN with the residue 371 substituted with Phosphothreonine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070880 name: SRBS2_HUMAN-Phosphoserine376 def: "Protein SRBS2_HUMAN with the residue 376 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070881 name: SRBS2_HUMAN-Phosphoserine750 def: "Protein SRBS2_HUMAN with the residue 750 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070882 name: SRBS2_HUMAN-Phosphoserine1017 def: "Protein SRBS2_HUMAN with the residue 1017 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070883 name: SRBS2_HUMAN-Phosphoserine1018 def: "Protein SRBS2_HUMAN with the residue 1018 substituted with Phosphoserine" [UniProtKB:O94875] comment: By similarity xref: UniProtKB:O94875 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:B0070884 name: SRC8_HUMAN-Phosphoserine113 def: "Protein SRC8_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070885 name: SRC8_HUMAN-Phosphoserine117 def: "Protein SRC8_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070886 name: SRC8_HUMAN-Phosphotyrosine141 def: "Protein SRC8_HUMAN with the residue 141 substituted with Phosphotyrosine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070887 name: SRC8_HUMAN-Phosphotyrosine215 def: "Protein SRC8_HUMAN with the residue 215 substituted with Phosphotyrosine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070888 name: SRC8_HUMAN-Phosphotyrosine334 def: "Protein SRC8_HUMAN with the residue 334 substituted with Phosphotyrosine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070889 name: SRC8_HUMAN-Phosphothreonine399 def: "Protein SRC8_HUMAN with the residue 399 substituted with Phosphothreonine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070890 name: SRC8_HUMAN-Phosphothreonine401 def: "Protein SRC8_HUMAN with the residue 401 substituted with Phosphothreonine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070891 name: SRC8_HUMAN-Phosphoserine405 def: "Protein SRC8_HUMAN with the residue 405 substituted with Phosphoserine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070892 name: SRC8_HUMAN-Phosphothreonine411 def: "Protein SRC8_HUMAN with the residue 411 substituted with Phosphothreonine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070893 name: SRC8_HUMAN-Phosphoserine417 def: "Protein SRC8_HUMAN with the residue 417 substituted with Phosphoserine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070894 name: SRC8_HUMAN-Phosphoserine418 def: "Protein SRC8_HUMAN with the residue 418 substituted with Phosphoserine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070895 name: SRC8_HUMAN-Phosphotyrosine421 def: "Protein SRC8_HUMAN with the residue 421 substituted with Phosphotyrosine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070896 name: SRC8_HUMAN-Phosphotyrosine446 def: "Protein SRC8_HUMAN with the residue 446 substituted with Phosphotyrosine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070897 name: SRC8_HUMAN-Phosphotyrosine453 def: "Protein SRC8_HUMAN with the residue 453 substituted with Phosphotyrosine" [UniProtKB:Q14247] xref: UniProtKB:Q14247 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063370 ! SRC8_HUMAN [Term] id: CCO:B0070898 name: SRCAP_HUMAN-Phosphoserine248 def: "Protein SRCAP_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:Q6ZRS2] xref: UniProtKB:Q6ZRS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0000813 ! histone acetyltransferase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057042 ! SRCAP_HUMAN [Term] id: CCO:B0070899 name: SRCAP_HUMAN-Phosphothreonine2258 def: "Protein SRCAP_HUMAN with the residue 2258 substituted with Phosphothreonine" [UniProtKB:Q6ZRS2] xref: UniProtKB:Q6ZRS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057042 ! SRCAP_HUMAN [Term] id: CCO:B0070900 name: SRCAP_HUMAN-Phosphothreonine2425 def: "Protein SRCAP_HUMAN with the residue 2425 substituted with Phosphothreonine" [UniProtKB:Q6ZRS2] xref: UniProtKB:Q6ZRS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057042 ! SRCAP_HUMAN [Term] id: CCO:B0070901 name: SRCAP_HUMAN-Phosphoserine2430 def: "Protein SRCAP_HUMAN with the residue 2430 substituted with Phosphoserine" [UniProtKB:Q6ZRS2] xref: UniProtKB:Q6ZRS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057042 ! SRCAP_HUMAN [Term] id: CCO:B0070902 name: SRCAP_HUMAN-Phosphoserine2869 def: "Protein SRCAP_HUMAN with the residue 2869 substituted with Phosphoserine" [UniProtKB:Q6ZRS2] xref: UniProtKB:Q6ZRS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057042 ! SRCAP_HUMAN [Term] id: CCO:B0070903 name: SRCAP_HUMAN-Phosphoserine3148 def: "Protein SRCAP_HUMAN with the residue 3148 substituted with Phosphoserine" [UniProtKB:Q6ZRS2] xref: UniProtKB:Q6ZRS2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057042 ! SRCAP_HUMAN [Term] id: CCO:B0070904 name: SRC_HUMAN-Phosphotyrosine439 def: "Protein SRC_HUMAN with the residue 439 substituted with Phosphotyrosine" [UniProtKB:P12931] xref: UniProtKB:P12931 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001380 ! SH3/SH2 adaptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0005635 ! SH2 domain binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000458 ! caveola relationship: transformation_of CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:B0070905 name: SRFB1_HUMAN-Phosphoserine203 def: "Protein SRFB1_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q8NEF9] xref: UniProtKB:Q8NEF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057590 ! SRFB1_HUMAN [Term] id: CCO:B0070906 name: SRFB1_HUMAN-Phosphotyrosine270 def: "Protein SRFB1_HUMAN with the residue 270 substituted with Phosphotyrosine" [UniProtKB:Q8NEF9] xref: UniProtKB:Q8NEF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057590 ! SRFB1_HUMAN [Term] id: CCO:B0070907 name: SRFB1_HUMAN-Phosphoserine273 def: "Protein SRFB1_HUMAN with the residue 273 substituted with Phosphoserine" [UniProtKB:Q8NEF9] xref: UniProtKB:Q8NEF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057590 ! SRFB1_HUMAN [Term] id: CCO:B0070908 name: SRFB1_HUMAN-Phosphoserine274 def: "Protein SRFB1_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:Q8NEF9] xref: UniProtKB:Q8NEF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057590 ! SRFB1_HUMAN [Term] id: CCO:B0070909 name: SRFB1_HUMAN-Phosphoserine276 def: "Protein SRFB1_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q8NEF9] xref: UniProtKB:Q8NEF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057590 ! SRFB1_HUMAN [Term] id: CCO:B0070910 name: SRFB1_HUMAN-Phosphoserine279 def: "Protein SRFB1_HUMAN with the residue 279 substituted with Phosphoserine" [UniProtKB:Q8NEF9] xref: UniProtKB:Q8NEF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057590 ! SRFB1_HUMAN [Term] id: CCO:B0070911 name: SRFB1_HUMAN-Phosphoserine281 def: "Protein SRFB1_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q8NEF9] xref: UniProtKB:Q8NEF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057590 ! SRFB1_HUMAN [Term] id: CCO:B0070912 name: SRGEF_HUMAN-Phosphoserine427 def: "Protein SRGEF_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:Q9UGK8] xref: UniProtKB:Q9UGK8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001392 ! Ran guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059123 ! SRGEF_HUMAN [Term] id: CCO:B0070913 name: SRGP1_HUMAN-Phosphoserine906 def: "Protein SRGP1_HUMAN with the residue 906 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070914 name: SRGP1_HUMAN-Phosphoserine917 def: "Protein SRGP1_HUMAN with the residue 917 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070915 name: SRGP1_HUMAN-Phosphoserine999 def: "Protein SRGP1_HUMAN with the residue 999 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070916 name: SRGP1_HUMAN-Phosphothreonine1001 def: "Protein SRGP1_HUMAN with the residue 1001 substituted with Phosphothreonine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070917 name: SRGP1_HUMAN-Phosphothreonine1004 def: "Protein SRGP1_HUMAN with the residue 1004 substituted with Phosphothreonine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070918 name: SRGP1_HUMAN-Phosphoserine1005 def: "Protein SRGP1_HUMAN with the residue 1005 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070919 name: SRGP1_HUMAN-Phosphoserine1008 def: "Protein SRGP1_HUMAN with the residue 1008 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070920 name: SRGP1_HUMAN-Phosphoserine1010 def: "Protein SRGP1_HUMAN with the residue 1010 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070921 name: SRGP1_HUMAN-Phosphoserine1029 def: "Protein SRGP1_HUMAN with the residue 1029 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070922 name: SRGP1_HUMAN-Phosphoserine1032 def: "Protein SRGP1_HUMAN with the residue 1032 substituted with Phosphoserine" [UniProtKB:Q7Z6B7] xref: UniProtKB:Q7Z6B7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057196 ! SRGP1_HUMAN [Term] id: CCO:B0070923 name: SRGP2_HUMAN-Phosphoserine602 def: "Protein SRGP2_HUMAN with the residue 602 substituted with Phosphoserine" [UniProtKB:O43295] xref: UniProtKB:O43295 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0054466 ! SRGP2_HUMAN [Term] id: CCO:B0070924 name: SRGP2_HUMAN-Phosphoserine1070 def: "Protein SRGP2_HUMAN with the residue 1070 substituted with Phosphoserine" [UniProtKB:O43295] comment: By similarity xref: UniProtKB:O43295 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054466 ! SRGP2_HUMAN [Term] id: CCO:B0070925 name: SRPK1_HUMAN-Phosphoserine51 def: "Protein SRPK1_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q96SB4] comment: by CK2; xref: UniProtKB:Q96SB4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002061 ! SRPK1_HUMAN [Term] id: CCO:B0070926 name: SRPK1_HUMAN-Phosphoserine309 def: "Protein SRPK1_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:Q96SB4] xref: UniProtKB:Q96SB4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002061 ! SRPK1_HUMAN [Term] id: CCO:B0070927 name: SRPK1_HUMAN-Phosphoserine311 def: "Protein SRPK1_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q96SB4] xref: UniProtKB:Q96SB4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002061 ! SRPK1_HUMAN [Term] id: CCO:B0070928 name: SRPK1_HUMAN-Phosphoserine555 def: "Protein SRPK1_HUMAN with the residue 555 substituted with Phosphoserine" [UniProtKB:Q96SB4] comment: by CK2; xref: UniProtKB:Q96SB4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002061 ! SRPK1_HUMAN [Term] id: CCO:B0070929 name: SRPK2_HUMAN-Phosphoserine494 def: "Protein SRPK2_HUMAN with the residue 494 substituted with Phosphoserine" [UniProtKB:P78362] xref: UniProtKB:P78362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022813 ! SRPK2_HUMAN [Term] id: CCO:B0070930 name: SRPK2_HUMAN-Phosphoserine497 def: "Protein SRPK2_HUMAN with the residue 497 substituted with Phosphoserine" [UniProtKB:P78362] xref: UniProtKB:P78362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022813 ! SRPK2_HUMAN [Term] id: CCO:B0070931 name: SSBP3_HUMAN-Phosphoserine347 def: "Protein SSBP3_HUMAN with the residue 347 substituted with Phosphoserine" [UniProtKB:Q9BWW4] xref: UniProtKB:Q9BWW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058541 ! SSBP3_HUMAN [Term] id: CCO:B0070932 name: SSBP3_HUMAN-Phosphothreonine360 def: "Protein SSBP3_HUMAN with the residue 360 substituted with Phosphothreonine" [UniProtKB:Q9BWW4] xref: UniProtKB:Q9BWW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058541 ! SSBP3_HUMAN [Term] id: CCO:B0070933 name: SSBP3_HUMAN-Phosphoserine381 def: "Protein SSBP3_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9BWW4] xref: UniProtKB:Q9BWW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058541 ! SSBP3_HUMAN [Term] id: CCO:B0070934 name: SSBP3_HUMAN-Phosphoserine387 def: "Protein SSBP3_HUMAN with the residue 387 substituted with Phosphoserine" [UniProtKB:Q9BWW4] xref: UniProtKB:Q9BWW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058541 ! SSBP3_HUMAN [Term] id: CCO:B0070935 name: SSBP4_HUMAN-Phosphoserine341 def: "Protein SSBP4_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:Q9BWG4] xref: UniProtKB:Q9BWG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062821 ! SSBP4_HUMAN [Term] id: CCO:B0070936 name: SSBP4_HUMAN-Phosphoserine342 def: "Protein SSBP4_HUMAN with the residue 342 substituted with Phosphoserine" [UniProtKB:Q9BWG4] xref: UniProtKB:Q9BWG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0062821 ! SSBP4_HUMAN [Term] id: CCO:B0070937 name: SSBP4_HUMAN-Phosphothreonine355 def: "Protein SSBP4_HUMAN with the residue 355 substituted with Phosphothreonine" [UniProtKB:Q9BWG4] xref: UniProtKB:Q9BWG4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062821 ! SSBP4_HUMAN [Term] id: CCO:B0070938 name: SSB_HUMAN-Phosphoserine79 def: "Protein SSB_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q04837] xref: UniProtKB:Q04837 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0055736 ! SSB_HUMAN [Term] id: CCO:B0070939 name: SSRA_HUMAN-Phosphoserine247 def: "Protein SSRA_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:P43307] xref: UniProtKB:P43307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006163 ! SSRA_HUMAN [Term] id: CCO:B0070940 name: SSRA_HUMAN-Phosphothreonine260 def: "Protein SSRA_HUMAN with the residue 260 substituted with Phosphothreonine" [UniProtKB:P43307] comment: By similarity xref: UniProtKB:P43307 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006163 ! SSRA_HUMAN [Term] id: CCO:B0070941 name: SSRP1_HUMAN-Phosphothreonine170 def: "Protein SSRP1_HUMAN with the residue 170 substituted with Phosphothreonine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0070942 name: SSRP1_HUMAN-Phosphoserine437 def: "Protein SSRP1_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:Q08945] xref: UniProtKB:Q08945 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:B0070943 name: SSX1_HUMAN-Phosphoserine181 def: "Protein SSX1_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q16384] xref: UniProtKB:Q16384 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056137 ! SSX1_HUMAN [Term] id: CCO:B0070944 name: ST17A_HUMAN-Phosphoserine28 def: "Protein ST17A_HUMAN with the residue 28 substituted with Phosphoserine" [UniProtKB:Q9UEE5] xref: UniProtKB:Q9UEE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0036514 ! ST17A_HUMAN [Term] id: CCO:B0070945 name: ST5_HUMAN-Phosphoserine622 def: "Protein ST5_HUMAN with the residue 622 substituted with Phosphoserine" [UniProtKB:P78524] xref: UniProtKB:P78524 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006063 ! ST5_HUMAN [Term] id: CCO:B0070946 name: STA5A_HUMAN-Phosphoserine193 def: "Protein STA5A_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:P42229] xref: UniProtKB:P42229 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0001609 ! STA5A_HUMAN [Term] id: CCO:B0070947 name: STABP_HUMAN-Phosphoserine2 def: "Protein STABP_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:O95630] xref: UniProtKB:O95630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054776 ! STABP_HUMAN [Term] id: CCO:B0070948 name: STABP_HUMAN-Phosphoserine48 def: "Protein STABP_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:O95630] xref: UniProtKB:O95630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054776 ! STABP_HUMAN [Term] id: CCO:B0070949 name: STABP_HUMAN-Phosphoserine243 def: "Protein STABP_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:O95630] xref: UniProtKB:O95630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054776 ! STABP_HUMAN [Term] id: CCO:B0070950 name: STABP_HUMAN-Phosphoserine245 def: "Protein STABP_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:O95630] xref: UniProtKB:O95630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0054776 ! STABP_HUMAN [Term] id: CCO:B0070951 name: STABP_HUMAN-Phosphoserine247 def: "Protein STABP_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:O95630] xref: UniProtKB:O95630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054776 ! STABP_HUMAN [Term] id: CCO:B0070952 name: STAG1_HUMAN-Phosphoserine1062 def: "Protein STAG1_HUMAN with the residue 1062 substituted with Phosphoserine" [UniProtKB:Q8WVM7] xref: UniProtKB:Q8WVM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002004 ! STAG1_HUMAN [Term] id: CCO:B0070953 name: STAG1_HUMAN-Phosphoserine1065 def: "Protein STAG1_HUMAN with the residue 1065 substituted with Phosphoserine" [UniProtKB:Q8WVM7] xref: UniProtKB:Q8WVM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002004 ! STAG1_HUMAN [Term] id: CCO:B0070954 name: STAG1_HUMAN-Phosphoserine1067 def: "Protein STAG1_HUMAN with the residue 1067 substituted with Phosphoserine" [UniProtKB:Q8WVM7] xref: UniProtKB:Q8WVM7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002004 ! STAG1_HUMAN [Term] id: CCO:B0070955 name: STAG2_HUMAN-Phosphoserine1058 def: "Protein STAG2_HUMAN with the residue 1058 substituted with Phosphoserine" [UniProtKB:Q8N3U4] xref: UniProtKB:Q8N3U4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001962 ! STAG2_HUMAN [Term] id: CCO:B0070956 name: STAG2_HUMAN-Phosphoserine1065 def: "Protein STAG2_HUMAN with the residue 1065 substituted with Phosphoserine" [UniProtKB:Q8N3U4] xref: UniProtKB:Q8N3U4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001962 ! STAG2_HUMAN [Term] id: CCO:B0070957 name: STAM1_HUMAN-Phosphoserine156 def: "Protein STAM1_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q92783] xref: UniProtKB:Q92783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058093 ! STAM1_HUMAN [Term] id: CCO:B0070958 name: STAM1_HUMAN-Phosphotyrosine198 def: "Protein STAM1_HUMAN with the residue 198 substituted with Phosphotyrosine" [UniProtKB:Q92783] xref: UniProtKB:Q92783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058093 ! STAM1_HUMAN [Term] id: CCO:B0070959 name: STAM1_HUMAN-Phosphotyrosine381 def: "Protein STAM1_HUMAN with the residue 381 substituted with Phosphotyrosine" [UniProtKB:Q92783] xref: UniProtKB:Q92783 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058093 ! STAM1_HUMAN [Term] id: CCO:B0070960 name: STAM2_HUMAN-Phosphotyrosine192 def: "Protein STAM2_HUMAN with the residue 192 substituted with Phosphotyrosine" [UniProtKB:O75886] xref: UniProtKB:O75886 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0062916 ! STAM2_HUMAN [Term] id: CCO:B0070961 name: STAM2_HUMAN-Phosphotyrosine371 def: "Protein STAM2_HUMAN with the residue 371 substituted with Phosphotyrosine" [UniProtKB:O75886] xref: UniProtKB:O75886 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062916 ! STAM2_HUMAN [Term] id: CCO:B0070962 name: STAM2_HUMAN-Phosphotyrosine374 def: "Protein STAM2_HUMAN with the residue 374 substituted with Phosphotyrosine" [UniProtKB:O75886] xref: UniProtKB:O75886 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062916 ! STAM2_HUMAN [Term] id: CCO:B0070963 name: STAP1_HUMAN-Phosphotyrosine168 def: "Protein STAP1_HUMAN with the residue 168 substituted with Phosphotyrosine" [UniProtKB:Q9ULZ2] comment: By similarity xref: UniProtKB:Q9ULZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0059239 ! STAP1_HUMAN [Term] id: CCO:B0070964 name: STAP1_HUMAN-Phosphoserine196 def: "Protein STAP1_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:Q9ULZ2] xref: UniProtKB:Q9ULZ2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059239 ! STAP1_HUMAN [Term] id: CCO:B0070965 name: STAT2_HUMAN-Phosphotyrosine690 def: "Protein STAT2_HUMAN with the residue 690 substituted with Phosphotyrosine" [UniProtKB:P52630] comment: by JAK; By similarity xref: UniProtKB:P52630 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023422 ! STAT2_HUMAN [Term] id: CCO:B0070966 name: STAT3_HUMAN-Phosphothreonine714 def: "Protein STAT3_HUMAN with the residue 714 substituted with Phosphothreonine" [UniProtKB:P40763] xref: UniProtKB:P40763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001376 ! hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:B0070967 name: STAT4_HUMAN-Phosphotyrosine693 def: "Protein STAT4_HUMAN with the residue 693 substituted with Phosphotyrosine" [UniProtKB:Q14765] comment: by JAK; By similarity xref: UniProtKB:Q14765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0023418 ! STAT4_HUMAN [Term] id: CCO:B0070968 name: STAT4_HUMAN-Phosphoserine721 def: "Protein STAT4_HUMAN with the residue 721 substituted with Phosphoserine" [UniProtKB:Q14765] comment: By similarity xref: UniProtKB:Q14765 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023418 ! STAT4_HUMAN [Term] id: CCO:B0070969 name: STF1_HUMAN-N6-acetyllysine34 def: "Protein STF1_HUMAN with the residue 34 substituted with N6-acetyllysine" [UniProtKB:Q13285] comment: Probable xref: UniProtKB:Q13285 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055892 ! STF1_HUMAN [Term] id: CCO:B0070970 name: STF1_HUMAN-N6-acetyllysine38 def: "Protein STF1_HUMAN with the residue 38 substituted with N6-acetyllysine" [UniProtKB:Q13285] comment: Probable xref: UniProtKB:Q13285 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055892 ! STF1_HUMAN [Term] id: CCO:B0070971 name: STF1_HUMAN-N6-acetyllysine72 def: "Protein STF1_HUMAN with the residue 72 substituted with N6-acetyllysine" [UniProtKB:Q13285] comment: Probable xref: UniProtKB:Q13285 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000295 ! steroid hormone receptor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001233 ! ligand-dependent nuclear receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001816 ! lipid binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055892 ! STF1_HUMAN [Term] id: CCO:B0070972 name: STF1_HUMAN-Phosphoserine203 def: "Protein STF1_HUMAN with the residue 203 substituted with Phosphoserine" [UniProtKB:Q13285] xref: UniProtKB:Q13285 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055892 ! STF1_HUMAN [Term] id: CCO:B0070973 name: STIL_HUMAN-Phosphoserine753 def: "Protein STIL_HUMAN with the residue 753 substituted with Phosphoserine" [UniProtKB:Q15468] xref: UniProtKB:Q15468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0056068 ! STIL_HUMAN [Term] id: CCO:B0070974 name: STIL_HUMAN-Phosphoserine1004 def: "Protein STIL_HUMAN with the residue 1004 substituted with Phosphoserine" [UniProtKB:Q15468] xref: UniProtKB:Q15468 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056068 ! STIL_HUMAN [Term] id: CCO:B0070975 name: STK3_HUMAN-N-acetylmethionine1 def: "Protein STK3_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q13188] xref: UniProtKB:Q13188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055885 ! STK3_HUMAN [Term] id: CCO:B0070976 name: STK3_HUMAN-Phosphothreonine180 def: "Protein STK3_HUMAN with the residue 180 substituted with Phosphothreonine" [UniProtKB:Q13188] comment: by autocatalysis; Probable xref: UniProtKB:Q13188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055885 ! STK3_HUMAN [Term] id: CCO:B0070977 name: STK3_HUMAN-Phosphoserine316 def: "Protein STK3_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q13188] xref: UniProtKB:Q13188 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055885 ! STK3_HUMAN [Term] id: CCO:B0070978 name: STRN3_HUMAN-Phosphoserine257 def: "Protein STRN3_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:Q13033] xref: UniProtKB:Q13033 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001737 ! STRN3_HUMAN [Term] id: CCO:B0070979 name: STRN4_HUMAN-Phosphoserine276 def: "Protein STRN4_HUMAN with the residue 276 substituted with Phosphoserine" [UniProtKB:Q9NRL3] xref: UniProtKB:Q9NRL3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001647 ! calmodulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0006352 ! STRN4_HUMAN [Term] id: CCO:B0070980 name: STUB1_HUMAN-Phosphoserine19 def: "Protein STUB1_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q9UNE7] xref: UniProtKB:Q9UNE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:B0070981 name: STUB1_HUMAN-Phosphoserine23 def: "Protein STUB1_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q9UNE7] xref: UniProtKB:Q9UNE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:B0070982 name: STUB1_HUMAN-Phosphoserine273 def: "Protein STUB1_HUMAN with the residue 273 substituted with Phosphoserine" [UniProtKB:Q9UNE7] xref: UniProtKB:Q9UNE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:B0070983 name: STUB1_HUMAN-Phosphothreonine276 def: "Protein STUB1_HUMAN with the residue 276 substituted with Phosphothreonine" [UniProtKB:Q9UNE7] xref: UniProtKB:Q9UNE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:B0070984 name: STX12_HUMAN-Phosphoserine139 def: "Protein STX12_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q86Y82] xref: UniProtKB:Q86Y82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057301 ! STX12_HUMAN [Term] id: CCO:B0070985 name: STX12_HUMAN-Phosphoserine142 def: "Protein STX12_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q86Y82] xref: UniProtKB:Q86Y82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001631 ! SNAP receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001950 ! phagocytic vesicle relationship: located_in CCO:C0002123 ! membrane raft relationship: transformation_of CCO:B0057301 ! STX12_HUMAN [Term] id: CCO:B0070986 name: STX1A_HUMAN-Phosphoserine14 def: "Protein STX1A_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q16623] xref: UniProtKB:Q16623 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056163 ! STX1A_HUMAN [Term] id: CCO:B0070987 name: STXB1_HUMAN-Phosphothreonine107 def: "Protein STXB1_HUMAN with the residue 107 substituted with Phosphothreonine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070988 name: STXB1_HUMAN-Phosphoserine142 def: "Protein STXB1_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070989 name: STXB1_HUMAN-Phosphotyrosine145 def: "Protein STXB1_HUMAN with the residue 145 substituted with Phosphotyrosine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070990 name: STXB1_HUMAN-Phosphoserine146 def: "Protein STXB1_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070991 name: STXB1_HUMAN-Phosphoserine345 def: "Protein STXB1_HUMAN with the residue 345 substituted with Phosphoserine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070992 name: STXB1_HUMAN-Phosphothreonine346 def: "Protein STXB1_HUMAN with the residue 346 substituted with Phosphothreonine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070993 name: STXB1_HUMAN-Phosphotyrosine473 def: "Protein STXB1_HUMAN with the residue 473 substituted with Phosphotyrosine" [UniProtKB:P61764] xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070994 name: STXB1_HUMAN-Phosphoserine507 def: "Protein STXB1_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070995 name: STXB1_HUMAN-Phosphoserine509 def: "Protein STXB1_HUMAN with the residue 509 substituted with Phosphoserine" [UniProtKB:P61764] comment: By similarity xref: UniProtKB:P61764 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:B0070996 name: SUFU_HUMAN-Phosphoserine481 def: "Protein SUFU_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:Q9UMX1] xref: UniProtKB:Q9UMX1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002232 ! SUFU_HUMAN [Term] id: CCO:B0070997 name: SURF2_HUMAN-Phosphothreonine154 def: "Protein SURF2_HUMAN with the residue 154 substituted with Phosphothreonine" [UniProtKB:Q15527] xref: UniProtKB:Q15527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063529 ! SURF2_HUMAN [Term] id: CCO:B0070998 name: SURF2_HUMAN-Phosphoserine155 def: "Protein SURF2_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q15527] xref: UniProtKB:Q15527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063529 ! SURF2_HUMAN [Term] id: CCO:B0070999 name: SURF2_HUMAN-Phosphoserine156 def: "Protein SURF2_HUMAN with the residue 156 substituted with Phosphoserine" [UniProtKB:Q15527] xref: UniProtKB:Q15527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063529 ! SURF2_HUMAN [Term] id: CCO:B0071000 name: SURF2_HUMAN-Phosphoserine163 def: "Protein SURF2_HUMAN with the residue 163 substituted with Phosphoserine" [UniProtKB:Q15527] xref: UniProtKB:Q15527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063529 ! SURF2_HUMAN [Term] id: CCO:B0071001 name: SURF2_HUMAN-Phosphothreonine190 def: "Protein SURF2_HUMAN with the residue 190 substituted with Phosphothreonine" [UniProtKB:Q15527] xref: UniProtKB:Q15527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063529 ! SURF2_HUMAN [Term] id: CCO:B0071002 name: SURF2_HUMAN-Phosphothreonine195 def: "Protein SURF2_HUMAN with the residue 195 substituted with Phosphothreonine" [UniProtKB:Q15527] xref: UniProtKB:Q15527 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0063529 ! SURF2_HUMAN [Term] id: CCO:B0071003 name: SUV92_HUMAN-Phosphoserine381 def: "Protein SUV92_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q9H5I1] xref: UniProtKB:Q9H5I1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000278 ! chromatin binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003617 ! histone-lysine N-methyltransferase activity relationship: has_function CCO:F0006291 ! histone lysine N-methyltransferase activity (H3-K9 specific) relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0002168 ! chromosome, centromeric region relationship: transformation_of CCO:B0002139 ! SUV92_HUMAN [Term] id: CCO:B0071004 name: SUV92_HUMAN-Phosphoserine382 def: "Protein SUV92_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:Q9H5I1] xref: UniProtKB:Q9H5I1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002139 ! SUV92_HUMAN [Term] id: CCO:B0071005 name: SUV92_HUMAN-Phosphoserine384 def: "Protein SUV92_HUMAN with the residue 384 substituted with Phosphoserine" [UniProtKB:Q9H5I1] xref: UniProtKB:Q9H5I1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002139 ! SUV92_HUMAN [Term] id: CCO:B0071006 name: SUV92_HUMAN-Phosphoserine388 def: "Protein SUV92_HUMAN with the residue 388 substituted with Phosphoserine" [UniProtKB:Q9H5I1] xref: UniProtKB:Q9H5I1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002139 ! SUV92_HUMAN [Term] id: CCO:B0071007 name: SUZ12_HUMAN-Phosphothreonine418 def: "Protein SUZ12_HUMAN with the residue 418 substituted with Phosphothreonine" [UniProtKB:Q15022] xref: UniProtKB:Q15022 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056036 ! SUZ12_HUMAN [Term] id: CCO:B0071008 name: SUZ12_HUMAN-Phosphoserine546 def: "Protein SUZ12_HUMAN with the residue 546 substituted with Phosphoserine" [UniProtKB:Q15022] xref: UniProtKB:Q15022 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056036 ! SUZ12_HUMAN [Term] id: CCO:B0071009 name: SUZ12_HUMAN-Phosphoserine583 def: "Protein SUZ12_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:Q15022] xref: UniProtKB:Q15022 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056036 ! SUZ12_HUMAN [Term] id: CCO:B0071010 name: SVIL_HUMAN-Phosphoserine221 def: "Protein SVIL_HUMAN with the residue 221 substituted with Phosphoserine" [UniProtKB:O95425] xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071011 name: SVIL_HUMAN-Phosphoserine245 def: "Protein SVIL_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:O95425] xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071012 name: SVIL_HUMAN-Phosphoserine263 def: "Protein SVIL_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:O95425] xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071013 name: SVIL_HUMAN-Phosphoserine270 def: "Protein SVIL_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:O95425] xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071014 name: SVIL_HUMAN-Phosphoserine673 def: "Protein SVIL_HUMAN with the residue 673 substituted with Phosphoserine" [UniProtKB:O95425] comment: By similarity xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071015 name: SVIL_HUMAN-Phosphoserine675 def: "Protein SVIL_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:O95425] comment: By similarity xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071016 name: SVIL_HUMAN-Phosphothreonine736 def: "Protein SVIL_HUMAN with the residue 736 substituted with Phosphothreonine" [UniProtKB:O95425] xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071017 name: SVIL_HUMAN-Phosphothreonine852 def: "Protein SVIL_HUMAN with the residue 852 substituted with Phosphothreonine" [UniProtKB:O95425] xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071018 name: SVIL_HUMAN-Phosphoserine1052 def: "Protein SVIL_HUMAN with the residue 1052 substituted with Phosphoserine" [UniProtKB:O95425] comment: By similarity xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001711 ! costamere relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071019 name: SVIL_HUMAN-Phosphothreonine1175 def: "Protein SVIL_HUMAN with the residue 1175 substituted with Phosphothreonine" [UniProtKB:O95425] xref: UniProtKB:O95425 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:B0071020 name: SYAC_HUMAN-N-acetylmethionine1 def: "Protein SYAC_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P49588] xref: UniProtKB:P49588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063185 ! SYAC_HUMAN [Term] id: CCO:B0071021 name: SYAC_HUMAN-Phosphoserine555 def: "Protein SYAC_HUMAN with the residue 555 substituted with Phosphoserine" [UniProtKB:P49588] xref: UniProtKB:P49588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063185 ! SYAC_HUMAN [Term] id: CCO:B0071022 name: SYAC_HUMAN-Phosphothreonine578 def: "Protein SYAC_HUMAN with the residue 578 substituted with Phosphothreonine" [UniProtKB:P49588] xref: UniProtKB:P49588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000015 ! tRNA binding relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001171 ! alanine-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0003435 ! ligase activity, forming aminoacyl-tRNA and related compounds relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063185 ! SYAC_HUMAN [Term] id: CCO:B0071023 name: SYAC_HUMAN-Phosphotyrosine580 def: "Protein SYAC_HUMAN with the residue 580 substituted with Phosphotyrosine" [UniProtKB:P49588] xref: UniProtKB:P49588 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063185 ! SYAC_HUMAN [Term] id: CCO:B0071024 name: SYCP1_HUMAN-Phosphotyrosine257 def: "Protein SYCP1_HUMAN with the residue 257 substituted with Phosphotyrosine" [UniProtKB:Q15431] xref: UniProtKB:Q15431 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000122 ! synaptonemal complex relationship: located_in CCO:C0000128 ! central element relationship: located_in CCO:C0000129 ! transverse filament relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0001808 ! SYCP1_HUMAN [Term] id: CCO:B0071025 name: SYDE1_HUMAN-Phosphoserine231 def: "Protein SYDE1_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q6ZW31] xref: UniProtKB:Q6ZW31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:B0071026 name: SYDE1_HUMAN-Phosphoserine235 def: "Protein SYDE1_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q6ZW31] xref: UniProtKB:Q6ZW31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:B0071027 name: SYDE1_HUMAN-Phosphoserine244 def: "Protein SYDE1_HUMAN with the residue 244 substituted with Phosphoserine" [UniProtKB:Q6ZW31] xref: UniProtKB:Q6ZW31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:B0071028 name: SYDE1_HUMAN-Phosphothreonine246 def: "Protein SYDE1_HUMAN with the residue 246 substituted with Phosphothreonine" [UniProtKB:Q6ZW31] xref: UniProtKB:Q6ZW31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001405 ! Rho GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:B0071029 name: SYDE1_HUMAN-Phosphoserine247 def: "Protein SYDE1_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:Q6ZW31] xref: UniProtKB:Q6ZW31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:B0071030 name: SYDE1_HUMAN-Phosphoserine681 def: "Protein SYDE1_HUMAN with the residue 681 substituted with Phosphoserine" [UniProtKB:Q6ZW31] xref: UniProtKB:Q6ZW31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:B0071031 name: SYDE1_HUMAN-Phosphoserine683 def: "Protein SYDE1_HUMAN with the residue 683 substituted with Phosphoserine" [UniProtKB:Q6ZW31] xref: UniProtKB:Q6ZW31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:B0071032 name: SYDE2_HUMAN-Phosphoserine544 def: "Protein SYDE2_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:Q5VT97] xref: UniProtKB:Q5VT97 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056649 ! SYDE2_HUMAN [Term] id: CCO:B0071033 name: SYEP_HUMAN-Phosphoserine885 def: "Protein SYEP_HUMAN with the residue 885 substituted with Phosphoserine" [UniProtKB:P07814] xref: UniProtKB:P07814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:B0071034 name: SYEP_HUMAN-Phosphoserine886 def: "Protein SYEP_HUMAN with the residue 886 substituted with Phosphoserine" [UniProtKB:P07814] xref: UniProtKB:P07814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:B0071035 name: SYEP_HUMAN-Phosphothreonine888 def: "Protein SYEP_HUMAN with the residue 888 substituted with Phosphothreonine" [UniProtKB:P07814] xref: UniProtKB:P07814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:B0071036 name: SYEP_HUMAN-Phosphoserine891 def: "Protein SYEP_HUMAN with the residue 891 substituted with Phosphoserine" [UniProtKB:P07814] xref: UniProtKB:P07814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001176 ! glutamate-tRNA ligase activity relationship: has_function CCO:F0001185 ! proline-tRNA ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000245 ! soluble fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:B0071037 name: SYEP_HUMAN-Phosphothreonine898 def: "Protein SYEP_HUMAN with the residue 898 substituted with Phosphothreonine" [UniProtKB:P07814] xref: UniProtKB:P07814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:B0071038 name: SYEP_HUMAN-Phosphoserine1000 def: "Protein SYEP_HUMAN with the residue 1000 substituted with Phosphoserine" [UniProtKB:P07814] xref: UniProtKB:P07814 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:B0071039 name: SYF1_HUMAN-Phosphoserine851 def: "Protein SYF1_HUMAN with the residue 851 substituted with Phosphoserine" [UniProtKB:Q9HCS7] xref: UniProtKB:Q9HCS7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0041548 ! SYF1_HUMAN [Term] id: CCO:B0071040 name: SYIC_HUMAN-Phosphoserine1051 def: "Protein SYIC_HUMAN with the residue 1051 substituted with Phosphoserine" [UniProtKB:P41252] xref: UniProtKB:P41252 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063045 ! SYIC_HUMAN [Term] id: CCO:B0071041 name: SYLC_HUMAN-Phosphoserine718 def: "Protein SYLC_HUMAN with the residue 718 substituted with Phosphoserine" [UniProtKB:Q9P2J5] xref: UniProtKB:Q9P2J5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063072 ! SYLC_HUMAN [Term] id: CCO:B0071042 name: SYLC_HUMAN-Phosphothreonine721 def: "Protein SYLC_HUMAN with the residue 721 substituted with Phosphothreonine" [UniProtKB:Q9P2J5] xref: UniProtKB:Q9P2J5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001170 ! aminoacyl-tRNA ligase activity relationship: has_function CCO:F0001181 ! leucine-tRNA ligase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063072 ! SYLC_HUMAN [Term] id: CCO:B0071043 name: SYLC_HUMAN-Phosphothreonine728 def: "Protein SYLC_HUMAN with the residue 728 substituted with Phosphothreonine" [UniProtKB:Q9P2J5] xref: UniProtKB:Q9P2J5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063072 ! SYLC_HUMAN [Term] id: CCO:B0071044 name: SYN1_HUMAN-Phosphoserine9 def: "Protein SYN1_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P17600] comment: by CaMK1 and PKA; xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071045 name: SYN1_HUMAN-Phosphoserine39 def: "Protein SYN1_HUMAN with the residue 39 substituted with Phosphoserine" [UniProtKB:P17600] xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071046 name: SYN1_HUMAN-Phosphoserine62 def: "Protein SYN1_HUMAN with the residue 62 substituted with Phosphoserine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071047 name: SYN1_HUMAN-Phosphoserine67 def: "Protein SYN1_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071048 name: SYN1_HUMAN-Phosphotyrosine312 def: "Protein SYN1_HUMAN with the residue 312 substituted with Phosphotyrosine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000522 ! synaptic vesicle relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071049 name: SYN1_HUMAN-Phosphothreonine337 def: "Protein SYN1_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071050 name: SYN1_HUMAN-Phosphoserine427 def: "Protein SYN1_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:P17600] xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071051 name: SYN1_HUMAN-Phosphoserine510 def: "Protein SYN1_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071052 name: SYN1_HUMAN-Phosphothreonine512 def: "Protein SYN1_HUMAN with the residue 512 substituted with Phosphothreonine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071053 name: SYN1_HUMAN-Phosphoserine520 def: "Protein SYN1_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071054 name: SYN1_HUMAN-Phosphoserine551 def: "Protein SYN1_HUMAN with the residue 551 substituted with Phosphoserine" [UniProtKB:P17600] xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071055 name: SYN1_HUMAN-Phosphoserine553 def: "Protein SYN1_HUMAN with the residue 553 substituted with Phosphoserine" [UniProtKB:P17600] xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071056 name: SYN1_HUMAN-Phosphoserine568 def: "Protein SYN1_HUMAN with the residue 568 substituted with Phosphoserine" [UniProtKB:P17600] comment: by CaMK2; xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071057 name: SYN1_HUMAN-Phosphoserine605 def: "Protein SYN1_HUMAN with the residue 605 substituted with Phosphoserine" [UniProtKB:P17600] comment: by CaMK2; xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071058 name: SYN1_HUMAN-Phosphoserine665 def: "Protein SYN1_HUMAN with the residue 665 substituted with Phosphoserine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071059 name: SYN1_HUMAN-Phosphoserine704 def: "Protein SYN1_HUMAN with the residue 704 substituted with Phosphoserine" [UniProtKB:P17600] comment: By similarity xref: UniProtKB:P17600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:B0071060 name: SYNC_HUMAN-Phosphoserine61 def: "Protein SYNC_HUMAN with the residue 61 substituted with Phosphoserine" [UniProtKB:O43776] xref: UniProtKB:O43776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063332 ! SYNC_HUMAN [Term] id: CCO:B0071061 name: SYNC_HUMAN-Phosphoserine482 def: "Protein SYNC_HUMAN with the residue 482 substituted with Phosphoserine" [UniProtKB:O43776] comment: By similarity xref: UniProtKB:O43776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063332 ! SYNC_HUMAN [Term] id: CCO:B0071062 name: SYNJ2_HUMAN-Phosphotyrosine130 def: "Protein SYNJ2_HUMAN with the residue 130 substituted with Phosphotyrosine" [UniProtKB:O15056] xref: UniProtKB:O15056 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000198 ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0051188 ! SYNJ2_HUMAN [Term] id: CCO:B0071063 name: SYVC_HUMAN-N-acetylserine2 def: "Protein SYVC_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P26640] xref: UniProtKB:P26640 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063057 ! SYVC_HUMAN [Term] id: CCO:B0071064 name: SYVC_HUMAN-Phosphotyrosine300 def: "Protein SYVC_HUMAN with the residue 300 substituted with Phosphotyrosine" [UniProtKB:P26640] xref: UniProtKB:P26640 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063057 ! SYVC_HUMAN [Term] id: CCO:B0071065 name: T22D3_HUMAN-Phosphoserine122 def: "Protein T22D3_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:Q99576] xref: UniProtKB:Q99576 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058425 ! T22D3_HUMAN [Term] id: CCO:B0071066 name: T22D4_HUMAN-Phosphoserine225 def: "Protein T22D4_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0071067 name: T22D4_HUMAN-Phosphothreonine229 def: "Protein T22D4_HUMAN with the residue 229 substituted with Phosphothreonine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0071068 name: T22D4_HUMAN-Phosphoserine233 def: "Protein T22D4_HUMAN with the residue 233 substituted with Phosphoserine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0071069 name: T22D4_HUMAN-Phosphoserine370 def: "Protein T22D4_HUMAN with the residue 370 substituted with Phosphoserine" [UniProtKB:Q9Y3Q8] xref: UniProtKB:Q9Y3Q8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:B0071070 name: T2EA_HUMAN-Phosphoserine268 def: "Protein T2EA_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:P29083] xref: UniProtKB:P29083 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000277 ! transcription factor TFIIE complex relationship: transformation_of CCO:B0055208 ! T2EA_HUMAN [Term] id: CCO:B0071071 name: T2FB_HUMAN-Phosphoserine142 def: "Protein T2FB_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:P13984] xref: UniProtKB:P13984 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000278 ! transcription factor TFIIF complex relationship: transformation_of CCO:B0020975 ! T2FB_HUMAN [Term] id: CCO:B0071072 name: T2FB_HUMAN-Phosphoserine248 def: "Protein T2FB_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:P13984] xref: UniProtKB:P13984 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020975 ! T2FB_HUMAN [Term] id: CCO:B0071073 name: T2R48_HUMAN-Phosphoserine114 def: "Protein T2R48_HUMAN with the residue 114 substituted with Phosphoserine" [UniProtKB:P59542] xref: UniProtKB:P59542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055585 ! T2R48_HUMAN [Term] id: CCO:B0071074 name: TA2R3_HUMAN-Phosphotyrosine246 def: "Protein TA2R3_HUMAN with the residue 246 substituted with Phosphotyrosine" [UniProtKB:Q9NYW6] xref: UniProtKB:Q9NYW6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058983 ! TA2R3_HUMAN [Term] id: CCO:B0071075 name: TAB2_HUMAN-Phosphoserine372 def: "Protein TAB2_HUMAN with the residue 372 substituted with Phosphoserine" [UniProtKB:Q9NYJ8] xref: UniProtKB:Q9NYJ8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:B0071076 name: TAB3_HUMAN-Phosphoserine60 def: "Protein TAB3_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q8N5C8] xref: UniProtKB:Q8N5C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063243 ! TAB3_HUMAN [Term] id: CCO:B0071077 name: TAB3_HUMAN-Phosphothreonine404 def: "Protein TAB3_HUMAN with the residue 404 substituted with Phosphothreonine" [UniProtKB:Q8N5C8] xref: UniProtKB:Q8N5C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063243 ! TAB3_HUMAN [Term] id: CCO:B0071078 name: TAB3_HUMAN-Phosphoserine408 def: "Protein TAB3_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:Q8N5C8] xref: UniProtKB:Q8N5C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0063243 ! TAB3_HUMAN [Term] id: CCO:B0071079 name: TAB3_HUMAN-Phosphoserine492 def: "Protein TAB3_HUMAN with the residue 492 substituted with Phosphoserine" [UniProtKB:Q8N5C8] xref: UniProtKB:Q8N5C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063243 ! TAB3_HUMAN [Term] id: CCO:B0071080 name: TACD1_HUMAN-Pyrrolidone carboxylic acid24 def: "Protein TACD1_HUMAN with the residue 24 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P16422] comment: Probable xref: UniProtKB:P16422 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063205 ! TACD1_HUMAN [Term] id: CCO:B0071081 name: TACD2_HUMAN-Phosphoserine322 def: "Protein TACD2_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:P09758] xref: UniProtKB:P09758 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054950 ! TACD2_HUMAN [Term] id: CCO:B0071082 name: TADBP_HUMAN-Phosphoserine91 def: "Protein TADBP_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q13148] xref: UniProtKB:Q13148 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063162 ! TADBP_HUMAN [Term] id: CCO:B0071083 name: TADBP_HUMAN-Phosphoserine92 def: "Protein TADBP_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q13148] xref: UniProtKB:Q13148 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063162 ! TADBP_HUMAN [Term] id: CCO:B0071084 name: TAF11_HUMAN-Phosphoserine60 def: "Protein TAF11_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:Q15544] xref: UniProtKB:Q15544 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056072 ! TAF11_HUMAN [Term] id: CCO:B0071085 name: TAF12_HUMAN-Phosphothreonine43 def: "Protein TAF12_HUMAN with the residue 43 substituted with Phosphothreonine" [UniProtKB:Q16514] xref: UniProtKB:Q16514 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0003499 ! transcription initiation factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: transformation_of CCO:B0018582 ! TAF12_HUMAN [Term] id: CCO:B0071086 name: TAF12_HUMAN-Phosphoserine51 def: "Protein TAF12_HUMAN with the residue 51 substituted with Phosphoserine" [UniProtKB:Q16514] xref: UniProtKB:Q16514 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018582 ! TAF12_HUMAN [Term] id: CCO:B0071087 name: TAF2_HUMAN-Phosphoserine1194 def: "Protein TAF2_HUMAN with the residue 1194 substituted with Phosphoserine" [UniProtKB:Q6P1X5] xref: UniProtKB:Q6P1X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001787 ! metallopeptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: transformation_of CCO:B0056881 ! TAF2_HUMAN [Term] id: CCO:B0071088 name: TAF2_HUMAN-Phosphoserine1196 def: "Protein TAF2_HUMAN with the residue 1196 substituted with Phosphoserine" [UniProtKB:Q6P1X5] xref: UniProtKB:Q6P1X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056881 ! TAF2_HUMAN [Term] id: CCO:B0071089 name: TAF2_HUMAN-Phosphoserine1198 def: "Protein TAF2_HUMAN with the residue 1198 substituted with Phosphoserine" [UniProtKB:Q6P1X5] xref: UniProtKB:Q6P1X5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056881 ! TAF2_HUMAN [Term] id: CCO:B0071090 name: TAF3_HUMAN-Phosphoserine183 def: "Protein TAF3_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071091 name: TAF3_HUMAN-Phosphoserine229 def: "Protein TAF3_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071092 name: TAF3_HUMAN-Phosphoserine236 def: "Protein TAF3_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071093 name: TAF3_HUMAN-Phosphoserine243 def: "Protein TAF3_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071094 name: TAF3_HUMAN-Phosphoserine267 def: "Protein TAF3_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071095 name: TAF3_HUMAN-Phosphoserine297 def: "Protein TAF3_HUMAN with the residue 297 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071096 name: TAF3_HUMAN-Phosphoserine410 def: "Protein TAF3_HUMAN with the residue 410 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071097 name: TAF3_HUMAN-Phosphoserine411 def: "Protein TAF3_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071098 name: TAF3_HUMAN-Phosphoserine413 def: "Protein TAF3_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071099 name: TAF3_HUMAN-Phosphoserine415 def: "Protein TAF3_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q5VWG9] xref: UniProtKB:Q5VWG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056663 ! TAF3_HUMAN [Term] id: CCO:B0071100 name: TAF6L_HUMAN-Phosphoserine85 def: "Protein TAF6L_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q9Y6J9] xref: UniProtKB:Q9Y6J9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0023501 ! TAF6L_HUMAN [Term] id: CCO:B0071101 name: TAF6_HUMAN-Phosphoserine626 def: "Protein TAF6_HUMAN with the residue 626 substituted with Phosphoserine" [UniProtKB:P49848] xref: UniProtKB:P49848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055440 ! TAF6_HUMAN [Term] id: CCO:B0071102 name: TAF6_HUMAN-Phosphoserine634 def: "Protein TAF6_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:P49848] xref: UniProtKB:P49848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055440 ! TAF6_HUMAN [Term] id: CCO:B0071103 name: TAF6_HUMAN-Phosphoserine636 def: "Protein TAF6_HUMAN with the residue 636 substituted with Phosphoserine" [UniProtKB:P49848] xref: UniProtKB:P49848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055440 ! TAF6_HUMAN [Term] id: CCO:B0071104 name: TAF6_HUMAN-Phosphoserine653 def: "Protein TAF6_HUMAN with the residue 653 substituted with Phosphoserine" [UniProtKB:P49848] xref: UniProtKB:P49848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055440 ! TAF6_HUMAN [Term] id: CCO:B0071105 name: TAF6_HUMAN-Phosphothreonine660 def: "Protein TAF6_HUMAN with the residue 660 substituted with Phosphothreonine" [UniProtKB:P49848] xref: UniProtKB:P49848 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055440 ! TAF6_HUMAN [Term] id: CCO:B0071106 name: TAF7_HUMAN-Phosphoserine171 def: "Protein TAF7_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q15545] xref: UniProtKB:Q15545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056073 ! TAF7_HUMAN [Term] id: CCO:B0071107 name: TAF7_HUMAN-Phosphoserine213 def: "Protein TAF7_HUMAN with the residue 213 substituted with Phosphoserine" [UniProtKB:Q15545] xref: UniProtKB:Q15545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056073 ! TAF7_HUMAN [Term] id: CCO:B0071108 name: TAF7_HUMAN-Phosphoserine227 def: "Protein TAF7_HUMAN with the residue 227 substituted with Phosphoserine" [UniProtKB:Q15545] xref: UniProtKB:Q15545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: transformation_of CCO:B0056073 ! TAF7_HUMAN [Term] id: CCO:B0071109 name: TAF7_HUMAN-Phosphoserine228 def: "Protein TAF7_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q15545] xref: UniProtKB:Q15545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056073 ! TAF7_HUMAN [Term] id: CCO:B0071110 name: TAF7_HUMAN-Phosphoserine229 def: "Protein TAF7_HUMAN with the residue 229 substituted with Phosphoserine" [UniProtKB:Q15545] xref: UniProtKB:Q15545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056073 ! TAF7_HUMAN [Term] id: CCO:B0071111 name: TAF7_HUMAN-Phosphoserine230 def: "Protein TAF7_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q15545] xref: UniProtKB:Q15545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056073 ! TAF7_HUMAN [Term] id: CCO:B0071112 name: TAF7_HUMAN-Phosphoserine264 def: "Protein TAF7_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q15545] xref: UniProtKB:Q15545 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056073 ! TAF7_HUMAN [Term] id: CCO:B0071113 name: TAF8_HUMAN-Phosphothreonine130 def: "Protein TAF8_HUMAN with the residue 130 substituted with Phosphothreonine" [UniProtKB:Q7Z7C8] xref: UniProtKB:Q7Z7C8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057209 ! TAF8_HUMAN [Term] id: CCO:B0071114 name: TAF9_HUMAN-Phosphothreonine159 def: "Protein TAF9_HUMAN with the residue 159 substituted with Phosphothreonine" [UniProtKB:Q16594] xref: UniProtKB:Q16594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:B0071115 name: TAF9_HUMAN-Phosphothreonine161 def: "Protein TAF9_HUMAN with the residue 161 substituted with Phosphothreonine" [UniProtKB:Q16594] xref: UniProtKB:Q16594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:B0071116 name: TAF9_HUMAN-Phosphothreonine178 def: "Protein TAF9_HUMAN with the residue 178 substituted with Phosphothreonine" [UniProtKB:Q16594] xref: UniProtKB:Q16594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:B0071117 name: TAF9_HUMAN-Phosphoserine181 def: "Protein TAF9_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q16594] xref: UniProtKB:Q16594 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000274 ! transcription factor TFIID complex relationship: transformation_of CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:B0071118 name: TAL1_HUMAN-Phosphoserine122 def: "Protein TAL1_HUMAN with the residue 122 substituted with Phosphoserine" [UniProtKB:P17542] comment: By similarity xref: UniProtKB:P17542 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0055090 ! TAL1_HUMAN [Term] id: CCO:B0071119 name: TANK_HUMAN-Phosphoserine129 def: "Protein TANK_HUMAN with the residue 129 substituted with Phosphoserine" [UniProtKB:Q92844] xref: UniProtKB:Q92844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:B0071120 name: TANK_HUMAN-Phosphoserine225 def: "Protein TANK_HUMAN with the residue 225 substituted with Phosphoserine" [UniProtKB:Q92844] xref: UniProtKB:Q92844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:B0071121 name: TANK_HUMAN-Phosphoserine228 def: "Protein TANK_HUMAN with the residue 228 substituted with Phosphoserine" [UniProtKB:Q92844] xref: UniProtKB:Q92844 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:B0071122 name: TAOK2_HUMAN-Phosphotyrosine43 def: "Protein TAOK2_HUMAN with the residue 43 substituted with Phosphotyrosine" [UniProtKB:Q9UL54] comment: By similarity xref: UniProtKB:Q9UL54 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019513 ! TAOK2_HUMAN [Term] id: CCO:B0071123 name: TAOK2_HUMAN-Phosphoserine181 def: "Protein TAOK2_HUMAN with the residue 181 substituted with Phosphoserine" [UniProtKB:Q9UL54] comment: By similarity xref: UniProtKB:Q9UL54 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019513 ! TAOK2_HUMAN [Term] id: CCO:B0071124 name: TAOK3_HUMAN-Phosphoserine324 def: "Protein TAOK3_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:Q9H2K8] xref: UniProtKB:Q9H2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019510 ! TAOK3_HUMAN [Term] id: CCO:B0071125 name: TAOK3_HUMAN-Phosphoserine331 def: "Protein TAOK3_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q9H2K8] xref: UniProtKB:Q9H2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019510 ! TAOK3_HUMAN [Term] id: CCO:B0071126 name: TAOK3_HUMAN-Phosphoserine346 def: "Protein TAOK3_HUMAN with the residue 346 substituted with Phosphoserine" [UniProtKB:Q9H2K8] comment: By similarity xref: UniProtKB:Q9H2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019510 ! TAOK3_HUMAN [Term] id: CCO:B0071127 name: TAOK3_HUMAN-Phosphoserine349 def: "Protein TAOK3_HUMAN with the residue 349 substituted with Phosphoserine" [UniProtKB:Q9H2K8] comment: By similarity xref: UniProtKB:Q9H2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019510 ! TAOK3_HUMAN [Term] id: CCO:B0071128 name: TAOK3_HUMAN-Phosphoserine442 def: "Protein TAOK3_HUMAN with the residue 442 substituted with Phosphoserine" [UniProtKB:Q9H2K8] xref: UniProtKB:Q9H2K8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0019510 ! TAOK3_HUMAN [Term] id: CCO:B0071129 name: TARA_HUMAN-Phosphothreonine810 def: "Protein TARA_HUMAN with the residue 810 substituted with Phosphothreonine" [UniProtKB:Q9H2D6] xref: UniProtKB:Q9H2D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058684 ! TARA_HUMAN [Term] id: CCO:B0071130 name: TARA_HUMAN-Phosphoserine1949 def: "Protein TARA_HUMAN with the residue 1949 substituted with Phosphoserine" [UniProtKB:Q9H2D6] xref: UniProtKB:Q9H2D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058684 ! TARA_HUMAN [Term] id: CCO:B0071131 name: TARA_HUMAN-Phosphoserine1955 def: "Protein TARA_HUMAN with the residue 1955 substituted with Phosphoserine" [UniProtKB:Q9H2D6] xref: UniProtKB:Q9H2D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058684 ! TARA_HUMAN [Term] id: CCO:B0071132 name: TAU_HUMAN-N-acetylalanine2 def: "Protein TAU_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:P10636] xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071133 name: TAU_HUMAN-Phosphoserine46 def: "Protein TAU_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071134 name: TAU_HUMAN-Phosphothreonine50 def: "Protein TAU_HUMAN with the residue 50 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071135 name: TAU_HUMAN-Phosphothreonine111 def: "Protein TAU_HUMAN with the residue 111 substituted with Phosphothreonine" [UniProtKB:P10636] comment: By similarity xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001679 ! microtubule binding relationship: has_function CCO:F0001687 ! lipoprotein binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005525 ! apolipoprotein E binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0000435 ! microtubule associated complex relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001004 ! axon relationship: located_in CCO:C0001006 ! growth cone relationship: located_in CCO:C0001706 ! cell projection relationship: located_in CCO:C0001946 ! tubulin complex relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071136 name: TAU_HUMAN-Phosphothreonine470 def: "Protein TAU_HUMAN with the residue 470 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071137 name: TAU_HUMAN-asparagine484 def: "Protein TAU_HUMAN with the residue 484 substituted with asparagine" [UniProtKB:P10636] comment: in tau and PHF-tau; partial; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071138 name: TAU_HUMAN-Phosphothreonine492 def: "Protein TAU_HUMAN with the residue 492 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071139 name: TAU_HUMAN-Phosphothreonine498 def: "Protein TAU_HUMAN with the residue 498 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071140 name: TAU_HUMAN-Phosphotyrosine514 def: "Protein TAU_HUMAN with the residue 514 substituted with Phosphotyrosine" [UniProtKB:P10636] comment: by TTBK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071141 name: TAU_HUMAN-Phosphoserine515 def: "Protein TAU_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK and TTBK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071142 name: TAU_HUMAN-Phosphoserine516 def: "Protein TAU_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK and TTBK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071143 name: TAU_HUMAN-Phosphoserine519 def: "Protein TAU_HUMAN with the residue 519 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK and TTBK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071144 name: TAU_HUMAN-Phosphothreonine522 def: "Protein TAU_HUMAN with the residue 522 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071145 name: TAU_HUMAN-Phosphothreonine529 def: "Protein TAU_HUMAN with the residue 529 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071146 name: TAU_HUMAN-Phosphoserine531 def: "Protein TAU_HUMAN with the residue 531 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PKA; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071147 name: TAU_HUMAN-Phosphothreonine534 def: "Protein TAU_HUMAN with the residue 534 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071148 name: TAU_HUMAN-Phosphothreonine548 def: "Protein TAU_HUMAN with the residue 548 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071149 name: TAU_HUMAN-Phosphoserine552 def: "Protein TAU_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071150 name: TAU_HUMAN-Phosphoserine554 def: "Protein TAU_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:P10636] comment: in PHF-tau; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071151 name: TAU_HUMAN-Phosphoserine579 def: "Protein TAU_HUMAN with the residue 579 substituted with Phosphoserine" [UniProtKB:P10636] comment: by MARK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071152 name: TAU_HUMAN-asparagine596 def: "Protein TAU_HUMAN with the residue 596 substituted with asparagine" [UniProtKB:P10636] comment: in tau and PHF-tau; partial; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071153 name: TAU_HUMAN-Phosphoserine610 def: "Protein TAU_HUMAN with the residue 610 substituted with Phosphoserine" [UniProtKB:P10636] comment: by MARK1; in PHF-tau; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071154 name: TAU_HUMAN-Phosphoserine622 def: "Protein TAU_HUMAN with the residue 622 substituted with Phosphoserine" [UniProtKB:P10636] comment: by MARK1; in PHF-tau; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071155 name: TAU_HUMAN-Phosphoserine641 def: "Protein TAU_HUMAN with the residue 641 substituted with Phosphoserine" [UniProtKB:P10636] comment: by MARK1; in PHF-tau; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071156 name: TAU_HUMAN-Phosphoserine673 def: "Protein TAU_HUMAN with the residue 673 substituted with Phosphoserine" [UniProtKB:P10636] comment: by MARK1; in PHF-tau; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071157 name: TAU_HUMAN-Phosphoserine713 def: "Protein TAU_HUMAN with the residue 713 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071158 name: TAU_HUMAN-Phosphoserine717 def: "Protein TAU_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:P10636] comment: By similarity xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071159 name: TAU_HUMAN-Phosphothreonine720 def: "Protein TAU_HUMAN with the residue 720 substituted with Phosphothreonine" [UniProtKB:P10636] xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071160 name: TAU_HUMAN-Phosphoserine721 def: "Protein TAU_HUMAN with the residue 721 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071161 name: TAU_HUMAN-Phosphoserine726 def: "Protein TAU_HUMAN with the residue 726 substituted with Phosphoserine" [UniProtKB:P10636] comment: By similarity xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071162 name: TAU_HUMAN-Phosphoserine729 def: "Protein TAU_HUMAN with the residue 729 substituted with Phosphoserine" [UniProtKB:P10636] comment: By similarity xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071163 name: TAU_HUMAN-Phosphothreonine731 def: "Protein TAU_HUMAN with the residue 731 substituted with Phosphothreonine" [UniProtKB:P10636] comment: By similarity xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071164 name: TAU_HUMAN-Phosphoserine733 def: "Protein TAU_HUMAN with the residue 733 substituted with Phosphoserine" [UniProtKB:P10636] comment: by CaMK2 and TTBK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071165 name: TAU_HUMAN-Phosphoserine739 def: "Protein TAU_HUMAN with the residue 739 substituted with Phosphoserine" [UniProtKB:P10636] comment: by PDPK and TTBK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071166 name: TAU_HUMAN-Phosphothreonine744 def: "Protein TAU_HUMAN with the residue 744 substituted with Phosphothreonine" [UniProtKB:P10636] comment: by TTBK1; xref: UniProtKB:P10636 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:B0071167 name: TB10A_HUMAN-Phosphoserine407 def: "Protein TB10A_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q9BXI6] xref: UniProtKB:Q9BXI6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004335 ! PDZ domain binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000459 ! microvillus relationship: transformation_of CCO:B0058554 ! TB10A_HUMAN [Term] id: CCO:B0071168 name: TB10B_HUMAN-Phosphoserine383 def: "Protein TB10B_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q4KMP7] xref: UniProtKB:Q4KMP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056319 ! TB10B_HUMAN [Term] id: CCO:B0071169 name: TB10B_HUMAN-Phosphoserine386 def: "Protein TB10B_HUMAN with the residue 386 substituted with Phosphoserine" [UniProtKB:Q4KMP7] xref: UniProtKB:Q4KMP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056319 ! TB10B_HUMAN [Term] id: CCO:B0071170 name: TB10B_HUMAN-Phosphoserine403 def: "Protein TB10B_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:Q4KMP7] xref: UniProtKB:Q4KMP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056319 ! TB10B_HUMAN [Term] id: CCO:B0071171 name: TB10B_HUMAN-Phosphoserine412 def: "Protein TB10B_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:Q4KMP7] xref: UniProtKB:Q4KMP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056319 ! TB10B_HUMAN [Term] id: CCO:B0071172 name: TB10B_HUMAN-Phosphoserine432 def: "Protein TB10B_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:Q4KMP7] xref: UniProtKB:Q4KMP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056319 ! TB10B_HUMAN [Term] id: CCO:B0071173 name: TB10B_HUMAN-Phosphothreonine434 def: "Protein TB10B_HUMAN with the residue 434 substituted with Phosphothreonine" [UniProtKB:Q4KMP7] xref: UniProtKB:Q4KMP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0056319 ! TB10B_HUMAN [Term] id: CCO:B0071174 name: TB182_HUMAN-Phosphoserine178 def: "Protein TB182_HUMAN with the residue 178 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071175 name: TB182_HUMAN-Phosphothreonine239 def: "Protein TB182_HUMAN with the residue 239 substituted with Phosphothreonine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071176 name: TB182_HUMAN-Phosphoserine287 def: "Protein TB182_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071177 name: TB182_HUMAN-Phosphoserine301 def: "Protein TB182_HUMAN with the residue 301 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071178 name: TB182_HUMAN-Phosphoserine429 def: "Protein TB182_HUMAN with the residue 429 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071179 name: TB182_HUMAN-Phosphoserine435 def: "Protein TB182_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071180 name: TB182_HUMAN-Phosphoserine494 def: "Protein TB182_HUMAN with the residue 494 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071181 name: TB182_HUMAN-Phosphoserine498 def: "Protein TB182_HUMAN with the residue 498 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071182 name: TB182_HUMAN-Phosphoserine712 def: "Protein TB182_HUMAN with the residue 712 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071183 name: TB182_HUMAN-Phosphoserine744 def: "Protein TB182_HUMAN with the residue 744 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071184 name: TB182_HUMAN-Phosphoserine762 def: "Protein TB182_HUMAN with the residue 762 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071185 name: TB182_HUMAN-Phosphoserine976 def: "Protein TB182_HUMAN with the residue 976 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071186 name: TB182_HUMAN-Phosphothreonine979 def: "Protein TB182_HUMAN with the residue 979 substituted with Phosphothreonine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071187 name: TB182_HUMAN-Phosphoserine983 def: "Protein TB182_HUMAN with the residue 983 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071188 name: TB182_HUMAN-Phosphoserine987 def: "Protein TB182_HUMAN with the residue 987 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071189 name: TB182_HUMAN-Phosphoserine1008 def: "Protein TB182_HUMAN with the residue 1008 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071190 name: TB182_HUMAN-Phosphoserine1133 def: "Protein TB182_HUMAN with the residue 1133 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071191 name: TB182_HUMAN-Phosphoserine1178 def: "Protein TB182_HUMAN with the residue 1178 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071192 name: TB182_HUMAN-Phosphoserine1181 def: "Protein TB182_HUMAN with the residue 1181 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071193 name: TB182_HUMAN-Phosphothreonine1282 def: "Protein TB182_HUMAN with the residue 1282 substituted with Phosphothreonine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071194 name: TB182_HUMAN-Phosphoserine1297 def: "Protein TB182_HUMAN with the residue 1297 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071195 name: TB182_HUMAN-Phosphoserine1328 def: "Protein TB182_HUMAN with the residue 1328 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071196 name: TB182_HUMAN-Phosphoserine1405 def: "Protein TB182_HUMAN with the residue 1405 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071197 name: TB182_HUMAN-Phosphoserine1439 def: "Protein TB182_HUMAN with the residue 1439 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071198 name: TB182_HUMAN-Phosphoserine1473 def: "Protein TB182_HUMAN with the residue 1473 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071199 name: TB182_HUMAN-Phosphoserine1476 def: "Protein TB182_HUMAN with the residue 1476 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071200 name: TB182_HUMAN-Phosphoserine1533 def: "Protein TB182_HUMAN with the residue 1533 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071201 name: TB182_HUMAN-Phosphoserine1545 def: "Protein TB182_HUMAN with the residue 1545 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071202 name: TB182_HUMAN-Phosphoserine1552 def: "Protein TB182_HUMAN with the residue 1552 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071203 name: TB182_HUMAN-Phosphoserine1558 def: "Protein TB182_HUMAN with the residue 1558 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071204 name: TB182_HUMAN-Phosphothreonine1563 def: "Protein TB182_HUMAN with the residue 1563 substituted with Phosphothreonine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071205 name: TB182_HUMAN-Phosphoserine1652 def: "Protein TB182_HUMAN with the residue 1652 substituted with Phosphoserine" [UniProtKB:Q9C0C2] xref: UniProtKB:Q9C0C2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0014982 ! TB182_HUMAN [Term] id: CCO:B0071206 name: TBA4A_HUMAN-Phosphoserine48 def: "Protein TBA4A_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:P68366] xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0071207 name: TBA4A_HUMAN-Phosphoserine340 def: "Protein TBA4A_HUMAN with the residue 340 substituted with Phosphoserine" [UniProtKB:P68366] xref: UniProtKB:P68366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005449 ! TBA4A_HUMAN [Term] id: CCO:B0071208 name: TBB2C_HUMAN-Phosphoserine322 def: "Protein TBB2C_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:P68371] xref: UniProtKB:P68371 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000427 ! GTPase activity relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0005648 ! MHC class I protein binding relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000434 ! microtubule relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0019878 ! TBB2C_HUMAN [Term] id: CCO:B0071209 name: TBC15_HUMAN-Phosphoserine70 def: "Protein TBC15_HUMAN with the residue 70 substituted with Phosphoserine" [UniProtKB:Q8TC07] xref: UniProtKB:Q8TC07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057910 ! TBC15_HUMAN [Term] id: CCO:B0071210 name: TBC15_HUMAN-Phosphotyrosine180 def: "Protein TBC15_HUMAN with the residue 180 substituted with Phosphotyrosine" [UniProtKB:Q8TC07] comment: By similarity xref: UniProtKB:Q8TC07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057910 ! TBC15_HUMAN [Term] id: CCO:B0071211 name: TBC15_HUMAN-Phosphoserine205 def: "Protein TBC15_HUMAN with the residue 205 substituted with Phosphoserine" [UniProtKB:Q8TC07] comment: By similarity xref: UniProtKB:Q8TC07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057910 ! TBC15_HUMAN [Term] id: CCO:B0071212 name: TBC15_HUMAN-Phosphotyrosine215 def: "Protein TBC15_HUMAN with the residue 215 substituted with Phosphotyrosine" [UniProtKB:Q8TC07] xref: UniProtKB:Q8TC07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057910 ! TBC15_HUMAN [Term] id: CCO:B0071213 name: TBC15_HUMAN-Phosphoserine675 def: "Protein TBC15_HUMAN with the residue 675 substituted with Phosphoserine" [UniProtKB:Q8TC07] xref: UniProtKB:Q8TC07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057910 ! TBC15_HUMAN [Term] id: CCO:B0071214 name: TBC15_HUMAN-Phosphothreonine689 def: "Protein TBC15_HUMAN with the residue 689 substituted with Phosphothreonine" [UniProtKB:Q8TC07] xref: UniProtKB:Q8TC07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057910 ! TBC15_HUMAN [Term] id: CCO:B0071215 name: TBC19_HUMAN-Phosphotyrosine25 def: "Protein TBC19_HUMAN with the residue 25 substituted with Phosphotyrosine" [UniProtKB:Q8N5T2] xref: UniProtKB:Q8N5T2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057478 ! TBC19_HUMAN [Term] id: CCO:B0071216 name: TBC23_HUMAN-Phosphoserine474 def: "Protein TBC23_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:Q9NUY8] xref: UniProtKB:Q9NUY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058928 ! TBC23_HUMAN [Term] id: CCO:B0071217 name: TBC23_HUMAN-Phosphoserine507 def: "Protein TBC23_HUMAN with the residue 507 substituted with Phosphoserine" [UniProtKB:Q9NUY8] xref: UniProtKB:Q9NUY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058928 ! TBC23_HUMAN [Term] id: CCO:B0071218 name: TBC23_HUMAN-Phosphothreonine514 def: "Protein TBC23_HUMAN with the residue 514 substituted with Phosphothreonine" [UniProtKB:Q9NUY8] xref: UniProtKB:Q9NUY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058928 ! TBC23_HUMAN [Term] id: CCO:B0071219 name: TBC25_HUMAN-Phosphoserine506 def: "Protein TBC25_HUMAN with the residue 506 substituted with Phosphoserine" [UniProtKB:Q3MII6] xref: UniProtKB:Q3MII6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0056262 ! TBC25_HUMAN [Term] id: CCO:B0071220 name: TBC9B_HUMAN-Phosphoserine411 def: "Protein TBC9B_HUMAN with the residue 411 substituted with Phosphoserine" [UniProtKB:Q66K14] xref: UniProtKB:Q66K14 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056695 ! TBC9B_HUMAN [Term] id: CCO:B0071221 name: TBC9B_HUMAN-Phosphoserine420 def: "Protein TBC9B_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:Q66K14] xref: UniProtKB:Q66K14 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056695 ! TBC9B_HUMAN [Term] id: CCO:B0071222 name: TBC9B_HUMAN-Phosphoserine432 def: "Protein TBC9B_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:Q66K14] xref: UniProtKB:Q66K14 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056695 ! TBC9B_HUMAN [Term] id: CCO:B0071223 name: TBC9B_HUMAN-Phosphoserine435 def: "Protein TBC9B_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:Q66K14] xref: UniProtKB:Q66K14 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056695 ! TBC9B_HUMAN [Term] id: CCO:B0071224 name: TBC9B_HUMAN-Phosphoserine463 def: "Protein TBC9B_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:Q66K14] xref: UniProtKB:Q66K14 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056695 ! TBC9B_HUMAN [Term] id: CCO:B0071225 name: TBCD1_HUMAN-Phosphotyrosine113 def: "Protein TBCD1_HUMAN with the residue 113 substituted with Phosphotyrosine" [UniProtKB:Q86TI0] xref: UniProtKB:Q86TI0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027581 ! TBCD1_HUMAN [Term] id: CCO:B0071226 name: TBCD5_HUMAN-Phosphothreonine42 def: "Protein TBCD5_HUMAN with the residue 42 substituted with Phosphothreonine" [UniProtKB:Q92609] xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071227 name: TBCD5_HUMAN-Phosphoserine43 def: "Protein TBCD5_HUMAN with the residue 43 substituted with Phosphoserine" [UniProtKB:Q92609] xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071228 name: TBCD5_HUMAN-Phosphoserine44 def: "Protein TBCD5_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q92609] xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071229 name: TBCD5_HUMAN-Phosphothreonine45 def: "Protein TBCD5_HUMAN with the residue 45 substituted with Phosphothreonine" [UniProtKB:Q92609] xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071230 name: TBCD5_HUMAN-Phosphoserine522 def: "Protein TBCD5_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q92609] comment: By similarity xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071231 name: TBCD5_HUMAN-Phosphoserine539 def: "Protein TBCD5_HUMAN with the residue 539 substituted with Phosphoserine" [UniProtKB:Q92609] xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071232 name: TBCD5_HUMAN-Phosphoserine541 def: "Protein TBCD5_HUMAN with the residue 541 substituted with Phosphoserine" [UniProtKB:Q92609] comment: By similarity xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071233 name: TBCD5_HUMAN-Phosphoserine544 def: "Protein TBCD5_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:Q92609] xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071234 name: TBCD5_HUMAN-Phosphoserine554 def: "Protein TBCD5_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:Q92609] xref: UniProtKB:Q92609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:B0071235 name: TBCD9_HUMAN-Phosphoserine997 def: "Protein TBCD9_HUMAN with the residue 997 substituted with Phosphoserine" [UniProtKB:Q6ZT07] xref: UniProtKB:Q6ZT07 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0057062 ! TBCD9_HUMAN [Term] id: CCO:B0071236 name: TBD2A_HUMAN-Phosphothreonine186 def: "Protein TBD2A_HUMAN with the residue 186 substituted with Phosphothreonine" [UniProtKB:Q9BYX2] xref: UniProtKB:Q9BYX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058586 ! TBD2A_HUMAN [Term] id: CCO:B0071237 name: TBD2A_HUMAN-Phosphoserine436 def: "Protein TBD2A_HUMAN with the residue 436 substituted with Phosphoserine" [UniProtKB:Q9BYX2] xref: UniProtKB:Q9BYX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058586 ! TBD2A_HUMAN [Term] id: CCO:B0071238 name: TBD2A_HUMAN-Phosphoserine904 def: "Protein TBD2A_HUMAN with the residue 904 substituted with Phosphoserine" [UniProtKB:Q9BYX2] xref: UniProtKB:Q9BYX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058586 ! TBD2A_HUMAN [Term] id: CCO:B0071239 name: TBD2A_HUMAN-Phosphoserine909 def: "Protein TBD2A_HUMAN with the residue 909 substituted with Phosphoserine" [UniProtKB:Q9BYX2] xref: UniProtKB:Q9BYX2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058586 ! TBD2A_HUMAN [Term] id: CCO:B0071240 name: TBD2B_HUMAN-Phosphoserine155 def: "Protein TBD2B_HUMAN with the residue 155 substituted with Phosphoserine" [UniProtKB:Q9UPU7] comment: By similarity xref: UniProtKB:Q9UPU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059268 ! TBD2B_HUMAN [Term] id: CCO:B0071241 name: TBD2B_HUMAN-Phosphoserine511 def: "Protein TBD2B_HUMAN with the residue 511 substituted with Phosphoserine" [UniProtKB:Q9UPU7] comment: By similarity xref: UniProtKB:Q9UPU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059268 ! TBD2B_HUMAN [Term] id: CCO:B0071242 name: TBD2B_HUMAN-Phosphoserine949 def: "Protein TBD2B_HUMAN with the residue 949 substituted with Phosphoserine" [UniProtKB:Q9UPU7] xref: UniProtKB:Q9UPU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059268 ! TBD2B_HUMAN [Term] id: CCO:B0071243 name: TBD2B_HUMAN-Phosphoserine957 def: "Protein TBD2B_HUMAN with the residue 957 substituted with Phosphoserine" [UniProtKB:Q9UPU7] xref: UniProtKB:Q9UPU7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0059268 ! TBD2B_HUMAN [Term] id: CCO:B0071244 name: TCAL1_HUMAN-Phosphoserine31 def: "Protein TCAL1_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071245 name: TCAL1_HUMAN-Phosphoserine32 def: "Protein TCAL1_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071246 name: TCAL1_HUMAN-Phosphoserine36 def: "Protein TCAL1_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071247 name: TCAL1_HUMAN-Phosphoserine37 def: "Protein TCAL1_HUMAN with the residue 37 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071248 name: TCAL1_HUMAN-Phosphoserine41 def: "Protein TCAL1_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071249 name: TCAL1_HUMAN-Phosphoserine42 def: "Protein TCAL1_HUMAN with the residue 42 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071250 name: TCAL1_HUMAN-Phosphoserine47 def: "Protein TCAL1_HUMAN with the residue 47 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071251 name: TCAL1_HUMAN-Phosphoserine48 def: "Protein TCAL1_HUMAN with the residue 48 substituted with Phosphoserine" [UniProtKB:Q15170] xref: UniProtKB:Q15170 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056048 ! TCAL1_HUMAN [Term] id: CCO:B0071252 name: TCAL3_HUMAN-Phosphoserine30 def: "Protein TCAL3_HUMAN with the residue 30 substituted with Phosphoserine" [UniProtKB:Q969E4] xref: UniProtKB:Q969E4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058127 ! TCAL3_HUMAN [Term] id: CCO:B0071253 name: TCAL3_HUMAN-Phosphoserine65 def: "Protein TCAL3_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q969E4] xref: UniProtKB:Q969E4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058127 ! TCAL3_HUMAN [Term] id: CCO:B0071254 name: TCAL4_HUMAN-Phosphotyrosine5 def: "Protein TCAL4_HUMAN with the residue 5 substituted with Phosphotyrosine" [UniProtKB:Q96EI5] xref: UniProtKB:Q96EI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058206 ! TCAL4_HUMAN [Term] id: CCO:B0071255 name: TCAL4_HUMAN-Phosphoserine102 def: "Protein TCAL4_HUMAN with the residue 102 substituted with Phosphoserine" [UniProtKB:Q96EI5] xref: UniProtKB:Q96EI5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058206 ! TCAL4_HUMAN [Term] id: CCO:B0071256 name: TCAL6_HUMAN-Phosphoserine125 def: "Protein TCAL6_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q6IPX3] xref: UniProtKB:Q6IPX3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056823 ! TCAL6_HUMAN [Term] id: CCO:B0071257 name: TCAM2_HUMAN-Phosphoserine16 def: "Protein TCAM2_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q86XR7] comment: by PKC/PRKCE; xref: UniProtKB:Q86XR7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057293 ! TCAM2_HUMAN [Term] id: CCO:B0071258 name: TCEA1_HUMAN-N-acetylmethionine1 def: "Protein TCEA1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P23193] xref: UniProtKB:P23193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055153 ! TCEA1_HUMAN [Term] id: CCO:B0071259 name: TCEA1_HUMAN-Phosphoserine81 def: "Protein TCEA1_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:P23193] xref: UniProtKB:P23193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055153 ! TCEA1_HUMAN [Term] id: CCO:B0071260 name: TCEA1_HUMAN-Phosphoserine97 def: "Protein TCEA1_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:P23193] xref: UniProtKB:P23193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055153 ! TCEA1_HUMAN [Term] id: CCO:B0071261 name: TCEA1_HUMAN-Phosphoserine100 def: "Protein TCEA1_HUMAN with the residue 100 substituted with Phosphoserine" [UniProtKB:P23193] xref: UniProtKB:P23193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055153 ! TCEA1_HUMAN [Term] id: CCO:B0071262 name: TCEA1_HUMAN-Phosphothreonine108 def: "Protein TCEA1_HUMAN with the residue 108 substituted with Phosphothreonine" [UniProtKB:P23193] xref: UniProtKB:P23193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000298 ! transcription elongation regulator activity relationship: has_function CCO:F0000317 ! translation elongation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: transformation_of CCO:B0055153 ! TCEA1_HUMAN [Term] id: CCO:B0071263 name: TCEA1_HUMAN-Phosphoserine110 def: "Protein TCEA1_HUMAN with the residue 110 substituted with Phosphoserine" [UniProtKB:P23193] xref: UniProtKB:P23193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055153 ! TCEA1_HUMAN [Term] id: CCO:B0071264 name: TCEA1_HUMAN-Phosphotyrosine126 def: "Protein TCEA1_HUMAN with the residue 126 substituted with Phosphotyrosine" [UniProtKB:P23193] xref: UniProtKB:P23193 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055153 ! TCEA1_HUMAN [Term] id: CCO:B0071265 name: TCF20_HUMAN-Phosphoserine31 def: "Protein TCF20_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071266 name: TCF20_HUMAN-Phosphoserine419 def: "Protein TCF20_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071267 name: TCF20_HUMAN-Phosphoserine430 def: "Protein TCF20_HUMAN with the residue 430 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071268 name: TCF20_HUMAN-Phosphoserine505 def: "Protein TCF20_HUMAN with the residue 505 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071269 name: TCF20_HUMAN-Phosphoserine538 def: "Protein TCF20_HUMAN with the residue 538 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071270 name: TCF20_HUMAN-Phosphotyrosine548 def: "Protein TCF20_HUMAN with the residue 548 substituted with Phosphotyrosine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071271 name: TCF20_HUMAN-Phosphoserine559 def: "Protein TCF20_HUMAN with the residue 559 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071272 name: TCF20_HUMAN-Phosphoserine574 def: "Protein TCF20_HUMAN with the residue 574 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071273 name: TCF20_HUMAN-Phosphoserine583 def: "Protein TCF20_HUMAN with the residue 583 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071274 name: TCF20_HUMAN-Phosphoserine627 def: "Protein TCF20_HUMAN with the residue 627 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071275 name: TCF20_HUMAN-Phosphoserine640 def: "Protein TCF20_HUMAN with the residue 640 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071276 name: TCF20_HUMAN-Phosphoserine871 def: "Protein TCF20_HUMAN with the residue 871 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071277 name: TCF20_HUMAN-Phosphoserine1005 def: "Protein TCF20_HUMAN with the residue 1005 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071278 name: TCF20_HUMAN-Phosphoserine1122 def: "Protein TCF20_HUMAN with the residue 1122 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071279 name: TCF20_HUMAN-Phosphoserine1335 def: "Protein TCF20_HUMAN with the residue 1335 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071280 name: TCF20_HUMAN-Phosphoserine1361 def: "Protein TCF20_HUMAN with the residue 1361 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071281 name: TCF20_HUMAN-Phosphoserine1522 def: "Protein TCF20_HUMAN with the residue 1522 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071282 name: TCF20_HUMAN-Phosphoserine1669 def: "Protein TCF20_HUMAN with the residue 1669 substituted with Phosphoserine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071283 name: TCF20_HUMAN-Phosphothreonine1671 def: "Protein TCF20_HUMAN with the residue 1671 substituted with Phosphothreonine" [UniProtKB:Q9UGU0] xref: UniProtKB:Q9UGU0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059126 ! TCF20_HUMAN [Term] id: CCO:B0071284 name: TCF25_HUMAN-Phosphoserine602 def: "Protein TCF25_HUMAN with the residue 602 substituted with Phosphoserine" [UniProtKB:Q9BQ70] xref: UniProtKB:Q9BQ70 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058475 ! TCF25_HUMAN [Term] id: CCO:B0071285 name: TCGAP_HUMAN-Phosphoserine570 def: "Protein TCGAP_HUMAN with the residue 570 substituted with Phosphoserine" [UniProtKB:O14559] comment: By similarity xref: UniProtKB:O14559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054352 ! TCGAP_HUMAN [Term] id: CCO:B0071286 name: TCGAP_HUMAN-Phosphotyrosine1169 def: "Protein TCGAP_HUMAN with the residue 1169 substituted with Phosphotyrosine" [UniProtKB:O14559] comment: By similarity xref: UniProtKB:O14559 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005562 ! phosphoinositide binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0054352 ! TCGAP_HUMAN [Term] id: CCO:B0071287 name: TCP4_HUMAN-Phosphoserine118 def: "Protein TCP4_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:P53999] xref: UniProtKB:P53999 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048676 ! TCP4_HUMAN [Term] id: CCO:B0071288 name: TCPA_HUMAN-N-acetylmethionine1 def: "Protein TCPA_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P17987] xref: UniProtKB:P17987 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063080 ! TCPA_HUMAN [Term] id: CCO:B0071289 name: TCPA_HUMAN-N6-acetyllysine400 def: "Protein TCPA_HUMAN with the residue 400 substituted with N6-acetyllysine" [UniProtKB:P17987] xref: UniProtKB:P17987 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063080 ! TCPA_HUMAN [Term] id: CCO:B0071290 name: TCPA_HUMAN-Phosphoserine544 def: "Protein TCPA_HUMAN with the residue 544 substituted with Phosphoserine" [UniProtKB:P17987] xref: UniProtKB:P17987 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063080 ! TCPA_HUMAN [Term] id: CCO:B0071291 name: TCPQ_HUMAN-Phosphoserine23 def: "Protein TCPQ_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:P50990] xref: UniProtKB:P50990 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0005696 ! ATPase activity, coupled relationship: has_function CCO:F0008055 ! unfolded protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:B0071292 name: TDIF2_HUMAN-Phosphoserine21 def: "Protein TDIF2_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071293 name: TDIF2_HUMAN-Phosphoserine117 def: "Protein TDIF2_HUMAN with the residue 117 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071294 name: TDIF2_HUMAN-Phosphoserine121 def: "Protein TDIF2_HUMAN with the residue 121 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071295 name: TDIF2_HUMAN-Phosphothreonine129 def: "Protein TDIF2_HUMAN with the residue 129 substituted with Phosphothreonine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071296 name: TDIF2_HUMAN-Phosphoserine141 def: "Protein TDIF2_HUMAN with the residue 141 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071297 name: TDIF2_HUMAN-Phosphoserine145 def: "Protein TDIF2_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071298 name: TDIF2_HUMAN-Phosphoserine148 def: "Protein TDIF2_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071299 name: TDIF2_HUMAN-Phosphoserine184 def: "Protein TDIF2_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071300 name: TDIF2_HUMAN-Phosphothreonine188 def: "Protein TDIF2_HUMAN with the residue 188 substituted with Phosphothreonine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071301 name: TDIF2_HUMAN-Phosphoserine189 def: "Protein TDIF2_HUMAN with the residue 189 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071302 name: TDIF2_HUMAN-Phosphoserine190 def: "Protein TDIF2_HUMAN with the residue 190 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071303 name: TDIF2_HUMAN-Phosphoserine191 def: "Protein TDIF2_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071304 name: TDIF2_HUMAN-Phosphoserine194 def: "Protein TDIF2_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071305 name: TDIF2_HUMAN-Phosphothreonine232 def: "Protein TDIF2_HUMAN with the residue 232 substituted with Phosphothreonine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071306 name: TDIF2_HUMAN-Phosphoserine324 def: "Protein TDIF2_HUMAN with the residue 324 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071307 name: TDIF2_HUMAN-Phosphoserine330 def: "Protein TDIF2_HUMAN with the residue 330 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071308 name: TDIF2_HUMAN-Phosphoserine381 def: "Protein TDIF2_HUMAN with the residue 381 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071309 name: TDIF2_HUMAN-Phosphoserine528 def: "Protein TDIF2_HUMAN with the residue 528 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071310 name: TDIF2_HUMAN-Phosphoserine532 def: "Protein TDIF2_HUMAN with the residue 532 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071311 name: TDIF2_HUMAN-Phosphoserine533 def: "Protein TDIF2_HUMAN with the residue 533 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071312 name: TDIF2_HUMAN-Phosphoserine543 def: "Protein TDIF2_HUMAN with the residue 543 substituted with Phosphoserine" [UniProtKB:Q5QJE6] xref: UniProtKB:Q5QJE6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056526 ! TDIF2_HUMAN [Term] id: CCO:B0071313 name: TE2IP_HUMAN-Phosphoserine36 def: "Protein TE2IP_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q9NYB0] xref: UniProtKB:Q9NYB0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:B0071314 name: TEAD1_HUMAN-Phosphoserine7 def: "Protein TEAD1_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:P28347] xref: UniProtKB:P28347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032277 ! TEAD1_HUMAN [Term] id: CCO:B0071315 name: TEAD1_HUMAN-Phosphoserine9 def: "Protein TEAD1_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:P28347] xref: UniProtKB:P28347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0032277 ! TEAD1_HUMAN [Term] id: CCO:B0071316 name: TEAD1_HUMAN-Phosphoserine11 def: "Protein TEAD1_HUMAN with the residue 11 substituted with Phosphoserine" [UniProtKB:P28347] xref: UniProtKB:P28347 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032277 ! TEAD1_HUMAN [Term] id: CCO:B0071317 name: TEBP_HUMAN-N6-acetyllysine33 def: "Protein TEBP_HUMAN with the residue 33 substituted with N6-acetyllysine" [UniProtKB:Q15185] xref: UniProtKB:Q15185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056049 ! TEBP_HUMAN [Term] id: CCO:B0071318 name: TEBP_HUMAN-Phosphoserine113 def: "Protein TEBP_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q15185] xref: UniProtKB:Q15185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056049 ! TEBP_HUMAN [Term] id: CCO:B0071319 name: TEBP_HUMAN-Phosphoserine118 def: "Protein TEBP_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q15185] xref: UniProtKB:Q15185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056049 ! TEBP_HUMAN [Term] id: CCO:B0071320 name: TEBP_HUMAN-Phosphoserine148 def: "Protein TEBP_HUMAN with the residue 148 substituted with Phosphoserine" [UniProtKB:Q15185] xref: UniProtKB:Q15185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056049 ! TEBP_HUMAN [Term] id: CCO:B0071321 name: TEBP_HUMAN-Phosphoserine151 def: "Protein TEBP_HUMAN with the residue 151 substituted with Phosphoserine" [UniProtKB:Q15185] xref: UniProtKB:Q15185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056049 ! TEBP_HUMAN [Term] id: CCO:B0071322 name: TEC_HUMAN-Phosphotyrosine206 def: "Protein TEC_HUMAN with the residue 206 substituted with Phosphotyrosine" [UniProtKB:P42680] comment: by autocatalysis; xref: UniProtKB:P42680 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055353 ! TEC_HUMAN [Term] id: CCO:B0071323 name: TEC_HUMAN-Phosphotyrosine519 def: "Protein TEC_HUMAN with the residue 519 substituted with Phosphotyrosine" [UniProtKB:P42680] comment: by autocatalysis; By similarity xref: UniProtKB:P42680 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055353 ! TEC_HUMAN [Term] id: CCO:B0071324 name: TEN1_HUMAN-Phosphoserine2580 def: "Protein TEN1_HUMAN with the residue 2580 substituted with Phosphoserine" [UniProtKB:Q9UKZ4] xref: UniProtKB:Q9UKZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059211 ! TEN1_HUMAN [Term] id: CCO:B0071325 name: TENC1_HUMAN-Phosphoserine455 def: "Protein TENC1_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q63HR2] xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071326 name: TENC1_HUMAN-Phosphoserine466 def: "Protein TENC1_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:Q63HR2] comment: By similarity xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071327 name: TENC1_HUMAN-Phosphoserine481 def: "Protein TENC1_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:Q63HR2] comment: By similarity xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071328 name: TENC1_HUMAN-Phosphotyrosine483 def: "Protein TENC1_HUMAN with the residue 483 substituted with Phosphotyrosine" [UniProtKB:Q63HR2] xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071329 name: TENC1_HUMAN-Phosphotyrosine770 def: "Protein TENC1_HUMAN with the residue 770 substituted with Phosphotyrosine" [UniProtKB:Q63HR2] xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071330 name: TENC1_HUMAN-Phosphoserine832 def: "Protein TENC1_HUMAN with the residue 832 substituted with Phosphoserine" [UniProtKB:Q63HR2] comment: By similarity xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071331 name: TENC1_HUMAN-Phosphoserine835 def: "Protein TENC1_HUMAN with the residue 835 substituted with Phosphoserine" [UniProtKB:Q63HR2] xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001086 ! phosphoprotein phosphatase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071332 name: TENC1_HUMAN-Phosphothreonine914 def: "Protein TENC1_HUMAN with the residue 914 substituted with Phosphothreonine" [UniProtKB:Q63HR2] comment: By similarity xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071333 name: TENC1_HUMAN-Phosphoserine1003 def: "Protein TENC1_HUMAN with the residue 1003 substituted with Phosphoserine" [UniProtKB:Q63HR2] xref: UniProtKB:Q63HR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056690 ! TENC1_HUMAN [Term] id: CCO:B0071334 name: TENR_HUMAN-Phosphoserine724 def: "Protein TENR_HUMAN with the residue 724 substituted with Phosphoserine" [UniProtKB:Q92752] comment: By similarity xref: UniProtKB:Q92752 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: transformation_of CCO:B0058089 ! TENR_HUMAN [Term] id: CCO:B0071335 name: TENX_HUMAN-Phosphothreonine1331 def: "Protein TENX_HUMAN with the residue 1331 substituted with Phosphothreonine" [UniProtKB:P22105] xref: UniProtKB:P22105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055141 ! TENX_HUMAN [Term] id: CCO:B0071336 name: TENX_HUMAN-Phosphothreonine1332 def: "Protein TENX_HUMAN with the residue 1332 substituted with Phosphothreonine" [UniProtKB:P22105] xref: UniProtKB:P22105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055141 ! TENX_HUMAN [Term] id: CCO:B0071337 name: TENX_HUMAN-Phosphotyrosine1417 def: "Protein TENX_HUMAN with the residue 1417 substituted with Phosphotyrosine" [UniProtKB:P22105] xref: UniProtKB:P22105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001407 ! receptor binding relationship: has_function CCO:F0001478 ! integrin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001780 ! heparin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000203 ! proteinaceous extracellular matrix relationship: located_in CCO:C0000207 ! fibrillar collagen relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0055141 ! TENX_HUMAN [Term] id: CCO:B0071338 name: TENX_HUMAN-Phosphoserine3738 def: "Protein TENX_HUMAN with the residue 3738 substituted with Phosphoserine" [UniProtKB:P22105] xref: UniProtKB:P22105 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055141 ! TENX_HUMAN [Term] id: CCO:B0071339 name: TERF1_HUMAN-Phosphoserine434 def: "Protein TERF1_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:P54274] xref: UniProtKB:P54274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001667 ! TERF1_HUMAN [Term] id: CCO:B0071340 name: TERF1_HUMAN-Phosphoserine435 def: "Protein TERF1_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:P54274] xref: UniProtKB:P54274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000283 ! double-stranded telomeric DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000388 ! spindle relationship: transformation_of CCO:B0001667 ! TERF1_HUMAN [Term] id: CCO:B0071341 name: TERF1_HUMAN-Phosphoserine437 def: "Protein TERF1_HUMAN with the residue 437 substituted with Phosphoserine" [UniProtKB:P54274] xref: UniProtKB:P54274 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001667 ! TERF1_HUMAN [Term] id: CCO:B0071342 name: TERT_HUMAN-Phosphothreonine1113 def: "Protein TERT_HUMAN with the residue 1113 substituted with Phosphothreonine" [UniProtKB:O14746] xref: UniProtKB:O14746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000306 ! telomerase activity relationship: has_function CCO:F0000307 ! telomeric template RNA reverse transcriptase activity relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0003351 ! nucleotidyltransferase activity relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: located_in CCO:C0000297 ! telomerase holoenzyme complex relationship: located_in CCO:C0001019 ! ribonucleoprotein complex relationship: transformation_of CCO:B0054372 ! TERT_HUMAN [Term] id: CCO:B0071343 name: TERT_HUMAN-Phosphoserine1125 def: "Protein TERT_HUMAN with the residue 1125 substituted with Phosphoserine" [UniProtKB:O14746] xref: UniProtKB:O14746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054372 ! TERT_HUMAN [Term] id: CCO:B0071344 name: TESK1_HUMAN-Phosphoserine220 def: "Protein TESK1_HUMAN with the residue 220 substituted with Phosphoserine" [UniProtKB:Q15569] comment: by autocatalysis; By similarity xref: UniProtKB:Q15569 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0004328 ! manganese ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063231 ! TESK1_HUMAN [Term] id: CCO:B0071345 name: TEX2_HUMAN-Phosphoserine162 def: "Protein TEX2_HUMAN with the residue 162 substituted with Phosphoserine" [UniProtKB:Q8IWB9] comment: By similarity xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071346 name: TEX2_HUMAN-Phosphoserine196 def: "Protein TEX2_HUMAN with the residue 196 substituted with Phosphoserine" [UniProtKB:Q8IWB9] xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071347 name: TEX2_HUMAN-Phosphothreonine262 def: "Protein TEX2_HUMAN with the residue 262 substituted with Phosphothreonine" [UniProtKB:Q8IWB9] comment: By similarity xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071348 name: TEX2_HUMAN-Phosphoserine265 def: "Protein TEX2_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q8IWB9] comment: By similarity xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071349 name: TEX2_HUMAN-Phosphoserine266 def: "Protein TEX2_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q8IWB9] xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071350 name: TEX2_HUMAN-Phosphothreonine269 def: "Protein TEX2_HUMAN with the residue 269 substituted with Phosphothreonine" [UniProtKB:Q8IWB9] comment: By similarity xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071351 name: TEX2_HUMAN-Phosphoserine270 def: "Protein TEX2_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q8IWB9] xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071352 name: TEX2_HUMAN-Phosphoserine295 def: "Protein TEX2_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q8IWB9] xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071353 name: TEX2_HUMAN-Phosphotyrosine609 def: "Protein TEX2_HUMAN with the residue 609 substituted with Phosphotyrosine" [UniProtKB:Q8IWB9] xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071354 name: TEX2_HUMAN-Phosphoserine751 def: "Protein TEX2_HUMAN with the residue 751 substituted with Phosphoserine" [UniProtKB:Q8IWB9] comment: By similarity xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071355 name: TEX2_HUMAN-Phosphoserine790 def: "Protein TEX2_HUMAN with the residue 790 substituted with Phosphoserine" [UniProtKB:Q8IWB9] comment: By similarity xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071356 name: TEX2_HUMAN-Phosphoserine794 def: "Protein TEX2_HUMAN with the residue 794 substituted with Phosphoserine" [UniProtKB:Q8IWB9] comment: By similarity xref: UniProtKB:Q8IWB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057358 ! TEX2_HUMAN [Term] id: CCO:B0071357 name: TF2AA_HUMAN-Phosphoserine280 def: "Protein TF2AA_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:P52655] comment: by TAF1; xref: UniProtKB:P52655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055488 ! TF2AA_HUMAN [Term] id: CCO:B0071358 name: TF2AA_HUMAN-Phosphoserine281 def: "Protein TF2AA_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:P52655] comment: by TAF1; xref: UniProtKB:P52655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000276 ! transcription factor TFIIA complex relationship: transformation_of CCO:B0055488 ! TF2AA_HUMAN [Term] id: CCO:B0071359 name: TF2AA_HUMAN-Phosphoserine316 def: "Protein TF2AA_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:P52655] comment: by TAF1; xref: UniProtKB:P52655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055488 ! TF2AA_HUMAN [Term] id: CCO:B0071360 name: TF2AA_HUMAN-Phosphoserine321 def: "Protein TF2AA_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:P52655] comment: by TAF1; xref: UniProtKB:P52655 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055488 ! TF2AA_HUMAN [Term] id: CCO:B0071361 name: TF2B_HUMAN-Phosphoserine76 def: "Protein TF2B_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q00403] xref: UniProtKB:Q00403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003090 ! general RNA polymerase II transcription factor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000272 ! transcription factor complex relationship: transformation_of CCO:B0022444 ! TF2B_HUMAN [Term] id: CCO:B0071362 name: TF2H5_HUMAN-Phosphothreonine69 def: "Protein TF2H5_HUMAN with the residue 69 substituted with Phosphothreonine" [UniProtKB:Q6ZYL4] xref: UniProtKB:Q6ZYL4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057091 ! TF2H5_HUMAN [Term] id: CCO:B0071363 name: TF3B_HUMAN-Phosphothreonine365 def: "Protein TF3B_HUMAN with the residue 365 substituted with Phosphothreonine" [UniProtKB:Q92994] xref: UniProtKB:Q92994 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050546 ! TF3B_HUMAN [Term] id: CCO:B0071364 name: TF3B_HUMAN-Phosphoserine450 def: "Protein TF3B_HUMAN with the residue 450 substituted with Phosphoserine" [UniProtKB:Q92994] xref: UniProtKB:Q92994 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0050546 ! TF3B_HUMAN [Term] id: CCO:B0071365 name: TF3C1_HUMAN-Phosphothreonine774 def: "Protein TF3C1_HUMAN with the residue 774 substituted with Phosphothreonine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0071366 name: TF3C1_HUMAN-Phosphothreonine1064 def: "Protein TF3C1_HUMAN with the residue 1064 substituted with Phosphothreonine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0071367 name: TF3C1_HUMAN-Phosphoserine1611 def: "Protein TF3C1_HUMAN with the residue 1611 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0071368 name: TF3C1_HUMAN-Phosphoserine1632 def: "Protein TF3C1_HUMAN with the residue 1632 substituted with Phosphoserine" [UniProtKB:Q12789] xref: UniProtKB:Q12789 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000297 ! RNA polymerase III transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000015 ! transcription factor TFIIIC complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:B0071369 name: TFAM_HUMAN-Phosphoserine193 def: "Protein TFAM_HUMAN with the residue 193 substituted with Phosphoserine" [UniProtKB:Q00059] xref: UniProtKB:Q00059 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055678 ! TFAM_HUMAN [Term] id: CCO:B0071370 name: TFAP4_HUMAN-Phosphoserine124 def: "Protein TFAP4_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q01664] xref: UniProtKB:Q01664 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055693 ! TFAP4_HUMAN [Term] id: CCO:B0071371 name: TFAP4_HUMAN-Phosphoserine139 def: "Protein TFAP4_HUMAN with the residue 139 substituted with Phosphoserine" [UniProtKB:Q01664] xref: UniProtKB:Q01664 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055693 ! TFAP4_HUMAN [Term] id: CCO:B0071372 name: TFG_HUMAN-N-acetylmethionine1 def: "Protein TFG_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:Q92734] xref: UniProtKB:Q92734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:B0071373 name: TFG_HUMAN-Phosphoserine197 def: "Protein TFG_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q92734] xref: UniProtKB:Q92734 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:B0071374 name: TFR1_HUMAN-Phosphotyrosine20 def: "Protein TFR1_HUMAN with the residue 20 substituted with Phosphotyrosine" [UniProtKB:P02786] xref: UniProtKB:P02786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001336 ! transferrin receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: located_in CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: transformation_of CCO:B0063056 ! TFR1_HUMAN [Term] id: CCO:B0071375 name: TFR1_HUMAN-Phosphoserine24 def: "Protein TFR1_HUMAN with the residue 24 substituted with Phosphoserine" [UniProtKB:P02786] xref: UniProtKB:P02786 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063056 ! TFR1_HUMAN [Term] id: CCO:B0071376 name: TGM2_HUMAN-Phosphotyrosine219 def: "Protein TGM2_HUMAN with the residue 219 substituted with Phosphotyrosine" [UniProtKB:P21980] xref: UniProtKB:P21980 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0048975 ! TGM2_HUMAN [Term] id: CCO:B0071377 name: TGS1_HUMAN-Phosphoserine55 def: "Protein TGS1_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:Q96RS0] xref: UniProtKB:Q96RS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:B0071378 name: TGS1_HUMAN-Phosphothreonine60 def: "Protein TGS1_HUMAN with the residue 60 substituted with Phosphothreonine" [UniProtKB:Q96RS0] xref: UniProtKB:Q96RS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:B0071379 name: TGS1_HUMAN-Phosphoserine85 def: "Protein TGS1_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q96RS0] xref: UniProtKB:Q96RS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:B0071380 name: TGS1_HUMAN-Phosphoserine89 def: "Protein TGS1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q96RS0] xref: UniProtKB:Q96RS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:B0071381 name: TGS1_HUMAN-Phosphoserine154 def: "Protein TGS1_HUMAN with the residue 154 substituted with Phosphoserine" [UniProtKB:Q96RS0] xref: UniProtKB:Q96RS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:B0071382 name: TGS1_HUMAN-Phosphoserine438 def: "Protein TGS1_HUMAN with the residue 438 substituted with Phosphoserine" [UniProtKB:Q96RS0] xref: UniProtKB:Q96RS0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:B0071383 name: THOC1_HUMAN-Phosphoserine2 def: "Protein THOC1_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q96FV9] xref: UniProtKB:Q96FV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000785 ! nuclear matrix relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0058211 ! THOC1_HUMAN [Term] id: CCO:B0071384 name: THOC1_HUMAN-Phosphoserine560 def: "Protein THOC1_HUMAN with the residue 560 substituted with Phosphoserine" [UniProtKB:Q96FV9] xref: UniProtKB:Q96FV9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058211 ! THOC1_HUMAN [Term] id: CCO:B0071385 name: THOC4_HUMAN-Phosphoserine8 def: "Protein THOC4_HUMAN with the residue 8 substituted with Phosphoserine" [UniProtKB:Q86V81] xref: UniProtKB:Q86V81 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017403 ! THOC4_HUMAN [Term] id: CCO:B0071386 name: THS7A_HUMAN-Phosphotyrosine1341 def: "Protein THS7A_HUMAN with the residue 1341 substituted with Phosphotyrosine" [UniProtKB:Q9UPZ6] xref: UniProtKB:Q9UPZ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063152 ! THS7A_HUMAN [Term] id: CCO:B0071387 name: THY1_HUMAN-Pyrrolidone carboxylic acid20 def: "Protein THY1_HUMAN with the residue 20 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P04216] comment: By similarity xref: UniProtKB:P04216 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054889 ! THY1_HUMAN [Term] id: CCO:B0071388 name: THYG_HUMAN-Sulfotyrosine24 def: "Protein THYG_HUMAN with the residue 24 substituted with Sulfotyrosine" [UniProtKB:P01266] xref: UniProtKB:P01266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054846 ! THYG_HUMAN [Term] id: CCO:B0071389 name: THYG_HUMAN-Thyroxine24 def: "Protein THYG_HUMAN with the residue 24 substituted with Thyroxine" [UniProtKB:P01266] xref: UniProtKB:P01266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054846 ! THYG_HUMAN [Term] id: CCO:B0071390 name: THYG_HUMAN-Thyroxine1310 def: "Protein THYG_HUMAN with the residue 1310 substituted with Thyroxine" [UniProtKB:P01266] xref: UniProtKB:P01266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054846 ! THYG_HUMAN [Term] id: CCO:B0071391 name: THYG_HUMAN-Thyroxine2573 def: "Protein THYG_HUMAN with the residue 2573 substituted with Thyroxine" [UniProtKB:P01266] xref: UniProtKB:P01266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054846 ! THYG_HUMAN [Term] id: CCO:B0071392 name: THYG_HUMAN-Thyroxine2587 def: "Protein THYG_HUMAN with the residue 2587 substituted with Thyroxine" [UniProtKB:P01266] xref: UniProtKB:P01266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054846 ! THYG_HUMAN [Term] id: CCO:B0071393 name: THYG_HUMAN-Triiodothyronine2766 def: "Protein THYG_HUMAN with the residue 2766 substituted with Triiodothyronine" [UniProtKB:P01266] xref: UniProtKB:P01266 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0054846 ! THYG_HUMAN [Term] id: CCO:B0071394 name: TIA1_HUMAN-Phosphoserine209 def: "Protein TIA1_HUMAN with the residue 209 substituted with Phosphoserine" [UniProtKB:P31483] xref: UniProtKB:P31483 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055244 ! TIA1_HUMAN [Term] id: CCO:B0071395 name: TIA1_HUMAN-Phosphoserine210 def: "Protein TIA1_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:P31483] xref: UniProtKB:P31483 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055244 ! TIA1_HUMAN [Term] id: CCO:B0071396 name: TIAM1_HUMAN-Phosphoserine231 def: "Protein TIAM1_HUMAN with the residue 231 substituted with Phosphoserine" [UniProtKB:Q13009] comment: By similarity xref: UniProtKB:Q13009 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0055865 ! TIAM1_HUMAN [Term] id: CCO:B0071397 name: TIAM1_HUMAN-Phosphotyrosine1323 def: "Protein TIAM1_HUMAN with the residue 1323 substituted with Phosphotyrosine" [UniProtKB:Q13009] comment: By similarity xref: UniProtKB:Q13009 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055865 ! TIAM1_HUMAN [Term] id: CCO:B0071398 name: TIAM2_HUMAN-Phosphothreonine1648 def: "Protein TIAM2_HUMAN with the residue 1648 substituted with Phosphothreonine" [UniProtKB:Q8IVF5] comment: By similarity xref: UniProtKB:Q8IVF5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057343 ! TIAM2_HUMAN [Term] id: CCO:B0071399 name: TIAR_HUMAN-Phosphotyrosine50 def: "Protein TIAR_HUMAN with the residue 50 substituted with Phosphotyrosine" [UniProtKB:Q01085] xref: UniProtKB:Q01085 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055684 ! TIAR_HUMAN [Term] id: CCO:B0071400 name: TIE1_HUMAN-Phosphotyrosine1007 def: "Protein TIE1_HUMAN with the residue 1007 substituted with Phosphotyrosine" [UniProtKB:P35590] comment: by autocatalysis; By similarity xref: UniProtKB:P35590 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055295 ! TIE1_HUMAN [Term] id: CCO:B0071401 name: TIE2_HUMAN-Phosphotyrosine992 def: "Protein TIE2_HUMAN with the residue 992 substituted with Phosphotyrosine" [UniProtKB:Q02763] comment: by autocatalysis; xref: UniProtKB:Q02763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055715 ! TIE2_HUMAN [Term] id: CCO:B0071402 name: TIF1B_HUMAN-Phosphoserine258 def: "Protein TIF1B_HUMAN with the residue 258 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0071403 name: TIF1B_HUMAN-Phosphoserine489 def: "Protein TIF1B_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0071404 name: TIF1B_HUMAN-Phosphoserine752 def: "Protein TIF1B_HUMAN with the residue 752 substituted with Phosphoserine" [UniProtKB:Q13263] xref: UniProtKB:Q13263 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:B0071405 name: TIGD4_HUMAN-Phosphotyrosine375 def: "Protein TIGD4_HUMAN with the residue 375 substituted with Phosphotyrosine" [UniProtKB:Q8IY51] xref: UniProtKB:Q8IY51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057383 ! TIGD4_HUMAN [Term] id: CCO:B0071406 name: TIGD4_HUMAN-Phosphoserine382 def: "Protein TIGD4_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:Q8IY51] xref: UniProtKB:Q8IY51 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057383 ! TIGD4_HUMAN [Term] id: CCO:B0071407 name: TINF2_HUMAN-Phosphoserine295 def: "Protein TINF2_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q9BSI4] xref: UniProtKB:Q9BSI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005630 ! telomeric DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000108 ! chromosome, telomeric region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000296 ! chromosome relationship: transformation_of CCO:B0006245 ! TINF2_HUMAN [Term] id: CCO:B0071408 name: TIPIN_HUMAN-Phosphoserine194 def: "Protein TIPIN_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q9BVW5] xref: UniProtKB:Q9BVW5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002104 ! TIPIN_HUMAN [Term] id: CCO:B0071409 name: TKN1_HUMAN-Methionine amide68 def: "Protein TKN1_HUMAN with the residue 68 substituted with Methionine amide" [UniProtKB:P20366] xref: UniProtKB:P20366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055119 ! TKN1_HUMAN [Term] id: CCO:B0071410 name: TKN1_HUMAN-Methionine amide107 def: "Protein TKN1_HUMAN with the residue 107 substituted with Methionine amide" [UniProtKB:P20366] xref: UniProtKB:P20366 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055119 ! TKN1_HUMAN [Term] id: CCO:B0071411 name: TLE2_HUMAN-Phosphoserine271 def: "Protein TLE2_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q04725] xref: UniProtKB:Q04725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:B0071412 name: TLE2_HUMAN-Phosphoserine281 def: "Protein TLE2_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:Q04725] xref: UniProtKB:Q04725 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:B0071413 name: TLE3_HUMAN-Phosphoserine311 def: "Protein TLE3_HUMAN with the residue 311 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0071414 name: TLE3_HUMAN-Phosphothreonine312 def: "Protein TLE3_HUMAN with the residue 312 substituted with Phosphothreonine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0071415 name: TLE3_HUMAN-Phosphothreonine319 def: "Protein TLE3_HUMAN with the residue 319 substituted with Phosphothreonine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0071416 name: TLE3_HUMAN-Phosphothreonine321 def: "Protein TLE3_HUMAN with the residue 321 substituted with Phosphothreonine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0071417 name: TLE3_HUMAN-Phosphoserine413 def: "Protein TLE3_HUMAN with the residue 413 substituted with Phosphoserine" [UniProtKB:Q04726] xref: UniProtKB:Q04726 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005690 ! TLE3_HUMAN [Term] id: CCO:B0071418 name: TLR3_HUMAN-Phosphotyrosine759 def: "Protein TLR3_HUMAN with the residue 759 substituted with Phosphotyrosine" [UniProtKB:O15455] xref: UniProtKB:O15455 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054438 ! TLR3_HUMAN [Term] id: CCO:B0071419 name: TLR3_HUMAN-Phosphotyrosine858 def: "Protein TLR3_HUMAN with the residue 858 substituted with Phosphotyrosine" [UniProtKB:O15455] xref: UniProtKB:O15455 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: transformation_of CCO:B0054438 ! TLR3_HUMAN [Term] id: CCO:B0071420 name: TLR7_HUMAN-Phosphoserine1010 def: "Protein TLR7_HUMAN with the residue 1010 substituted with Phosphoserine" [UniProtKB:Q9NYK1] comment: By similarity xref: UniProtKB:Q9NYK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0000312 ! single-stranded RNA binding relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001240 ! transmembrane receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005568 ! siRNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000713 ! endosome membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001148 ! intrinsic to membrane relationship: transformation_of CCO:B0058964 ! TLR7_HUMAN [Term] id: CCO:B0071421 name: TMEDA_HUMAN-Omega-N-methylated arginine171 def: "Protein TMEDA_HUMAN with the residue 171 substituted with Omega-N-methylated arginine" [UniProtKB:P49755] comment: By similarity xref: UniProtKB:P49755 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000021 ! Golgi membrane relationship: located_in CCO:C0000373 ! microsome relationship: located_in CCO:C0000374 ! ER-Golgi intermediate compartment relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000380 ! cis-Golgi network relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0001642 ! melanosome relationship: located_in CCO:C0001661 ! zymogen granule membrane relationship: transformation_of CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:B0071422 name: TMEDA_HUMAN-Omega-N-methylated arginine176 def: "Protein TMEDA_HUMAN with the residue 176 substituted with Omega-N-methylated arginine" [UniProtKB:P49755] comment: By similarity xref: UniProtKB:P49755 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:B0071423 name: TMF1_HUMAN-Phosphoserine112 def: "Protein TMF1_HUMAN with the residue 112 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071424 name: TMF1_HUMAN-Phosphoserine328 def: "Protein TMF1_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071425 name: TMF1_HUMAN-Phosphoserine338 def: "Protein TMF1_HUMAN with the residue 338 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071426 name: TMF1_HUMAN-Phosphoserine344 def: "Protein TMF1_HUMAN with the residue 344 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071427 name: TMF1_HUMAN-Phosphotyrosine866 def: "Protein TMF1_HUMAN with the residue 866 substituted with Phosphotyrosine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071428 name: TMF1_HUMAN-Phosphotyrosine877 def: "Protein TMF1_HUMAN with the residue 877 substituted with Phosphotyrosine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071429 name: TMF1_HUMAN-Phosphoserine925 def: "Protein TMF1_HUMAN with the residue 925 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071430 name: TMF1_HUMAN-Phosphothreonine929 def: "Protein TMF1_HUMAN with the residue 929 substituted with Phosphothreonine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071431 name: TMF1_HUMAN-Phosphoserine933 def: "Protein TMF1_HUMAN with the residue 933 substituted with Phosphoserine" [UniProtKB:P82094] xref: UniProtKB:P82094 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:B0071432 name: TMM22_HUMAN-Phosphoserine409 def: "Protein TMM22_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q8TBE7] xref: UniProtKB:Q8TBE7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063538 ! TMM22_HUMAN [Term] id: CCO:B0071433 name: TMM51_HUMAN-Phosphoserine115 def: "Protein TMM51_HUMAN with the residue 115 substituted with Phosphoserine" [UniProtKB:Q9NW97] comment: By similarity xref: UniProtKB:Q9NW97 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0063522 ! TMM51_HUMAN [Term] id: CCO:B0071434 name: TMOD3_HUMAN-Phosphoserine25 def: "Protein TMOD3_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q9NYL9] xref: UniProtKB:Q9NYL9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001654 ! tropomyosin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0063097 ! TMOD3_HUMAN [Term] id: CCO:B0071435 name: TMOD3_HUMAN-Phosphoserine71 def: "Protein TMOD3_HUMAN with the residue 71 substituted with Phosphoserine" [UniProtKB:Q9NYL9] comment: By similarity xref: UniProtKB:Q9NYL9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063097 ! TMOD3_HUMAN [Term] id: CCO:B0071436 name: TNAP1_HUMAN-Phosphoserine278 def: "Protein TNAP1_HUMAN with the residue 278 substituted with Phosphoserine" [UniProtKB:Q13829] xref: UniProtKB:Q13829 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055946 ! TNAP1_HUMAN [Term] id: CCO:B0071437 name: TNAP1_HUMAN-Phosphoserine280 def: "Protein TNAP1_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q13829] xref: UniProtKB:Q13829 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001517 ! voltage-gated potassium channel activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000527 ! voltage-gated potassium channel complex relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0055946 ! TNAP1_HUMAN [Term] id: CCO:B0071438 name: TNAP3_HUMAN-Phosphoserine575 def: "Protein TNAP3_HUMAN with the residue 575 substituted with Phosphoserine" [UniProtKB:P21580] xref: UniProtKB:P21580 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055134 ! TNAP3_HUMAN [Term] id: CCO:B0071439 name: TNIK_HUMAN-Phosphoserine678 def: "Protein TNIK_HUMAN with the residue 678 substituted with Phosphoserine" [UniProtKB:Q9UKE5] xref: UniProtKB:Q9UKE5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:B0071440 name: TNKS1_HUMAN-Phosphoserine365 def: "Protein TNKS1_HUMAN with the residue 365 substituted with Phosphoserine" [UniProtKB:O95271] xref: UniProtKB:O95271 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:B0071441 name: TNNC1_HUMAN-N-acetylmethionine1 def: "Protein TNNC1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P63316] xref: UniProtKB:P63316 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004625 ! troponin I binding relationship: has_function CCO:F0004626 ! troponin T binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0007330 ! calcium-dependent protein binding relationship: has_function CCO:F0008035 ! actin filament binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000424 ! troponin complex relationship: transformation_of CCO:B0055634 ! TNNC1_HUMAN [Term] id: CCO:B0071442 name: TNR11_HUMAN-Phosphoserine463 def: "Protein TNR11_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:Q9Y6Q6] xref: UniProtKB:Q9Y6Q6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0059413 ! TNR11_HUMAN [Term] id: CCO:B0071443 name: TOM1_HUMAN-Phosphoserine130 def: "Protein TOM1_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:O60784] xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071444 name: TOM1_HUMAN-Phosphoserine131 def: "Protein TOM1_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:O60784] xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071445 name: TOM1_HUMAN-Phosphothreonine139 def: "Protein TOM1_HUMAN with the residue 139 substituted with Phosphothreonine" [UniProtKB:O60784] xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071446 name: TOM1_HUMAN-Phosphothreonine174 def: "Protein TOM1_HUMAN with the residue 174 substituted with Phosphothreonine" [UniProtKB:O60784] comment: By similarity xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071447 name: TOM1_HUMAN-Phosphoserine176 def: "Protein TOM1_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:O60784] comment: By similarity xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071448 name: TOM1_HUMAN-Phosphoserine180 def: "Protein TOM1_HUMAN with the residue 180 substituted with Phosphoserine" [UniProtKB:O60784] comment: By similarity xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071449 name: TOM1_HUMAN-Phosphoserine461 def: "Protein TOM1_HUMAN with the residue 461 substituted with Phosphoserine" [UniProtKB:O60784] xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071450 name: TOM1_HUMAN-Phosphoserine462 def: "Protein TOM1_HUMAN with the residue 462 substituted with Phosphoserine" [UniProtKB:O60784] xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071451 name: TOM1_HUMAN-Phosphoserine464 def: "Protein TOM1_HUMAN with the residue 464 substituted with Phosphoserine" [UniProtKB:O60784] xref: UniProtKB:O60784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:B0071452 name: TOP3A_HUMAN-Phosphoserine54 def: "Protein TOP3A_HUMAN with the residue 54 substituted with Phosphoserine" [UniProtKB:Q13472] xref: UniProtKB:Q13472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001753 ! TOP3A_HUMAN [Term] id: CCO:B0071453 name: TOP3A_HUMAN-Phosphoserine771 def: "Protein TOP3A_HUMAN with the residue 771 substituted with Phosphoserine" [UniProtKB:Q13472] xref: UniProtKB:Q13472 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001753 ! TOP3A_HUMAN [Term] id: CCO:B0071454 name: TOPK_HUMAN-Phosphothreonine24 def: "Protein TOPK_HUMAN with the residue 24 substituted with Phosphothreonine" [UniProtKB:Q96KB5] xref: UniProtKB:Q96KB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002045 ! TOPK_HUMAN [Term] id: CCO:B0071455 name: TOPK_HUMAN-Phosphoserine32 def: "Protein TOPK_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:Q96KB5] xref: UniProtKB:Q96KB5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002045 ! TOPK_HUMAN [Term] id: CCO:B0071456 name: TOX4_HUMAN-Phosphoserine182 def: "Protein TOX4_HUMAN with the residue 182 substituted with Phosphoserine" [UniProtKB:O94842] comment: By similarity xref: UniProtKB:O94842 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000112 ! chromatin relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054703 ! TOX4_HUMAN [Term] id: CCO:B0071457 name: TP53B_HUMAN-Phosphoserine222 def: "Protein TP53B_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071458 name: TP53B_HUMAN-Phosphoserine265 def: "Protein TP53B_HUMAN with the residue 265 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071459 name: TP53B_HUMAN-Phosphoserine395 def: "Protein TP53B_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071460 name: TP53B_HUMAN-Phosphoserine398 def: "Protein TP53B_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071461 name: TP53B_HUMAN-Phosphoserine809 def: "Protein TP53B_HUMAN with the residue 809 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071462 name: TP53B_HUMAN-Phosphoserine876 def: "Protein TP53B_HUMAN with the residue 876 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071463 name: TP53B_HUMAN-Phosphoserine877 def: "Protein TP53B_HUMAN with the residue 877 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071464 name: TP53B_HUMAN-Phosphoserine1101 def: "Protein TP53B_HUMAN with the residue 1101 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071465 name: TP53B_HUMAN-Phosphoserine1368 def: "Protein TP53B_HUMAN with the residue 1368 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071466 name: TP53B_HUMAN-Phosphothreonine1372 def: "Protein TP53B_HUMAN with the residue 1372 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071467 name: TP53B_HUMAN-Phosphoserine1435 def: "Protein TP53B_HUMAN with the residue 1435 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071468 name: TP53B_HUMAN-Phosphothreonine1609 def: "Protein TP53B_HUMAN with the residue 1609 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071469 name: TP53B_HUMAN-Phosphoserine1618 def: "Protein TP53B_HUMAN with the residue 1618 substituted with Phosphoserine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071470 name: TP53B_HUMAN-Phosphothreonine1672 def: "Protein TP53B_HUMAN with the residue 1672 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071471 name: TP53B_HUMAN-Phosphothreonine1709 def: "Protein TP53B_HUMAN with the residue 1709 substituted with Phosphothreonine" [UniProtKB:Q12888] xref: UniProtKB:Q12888 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:B0071472 name: TPD52_HUMAN-Phosphoserine171 def: "Protein TPD52_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:P55327] xref: UniProtKB:P55327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005373 ! TPD52_HUMAN [Term] id: CCO:B0071473 name: TPD52_HUMAN-Phosphothreonine173 def: "Protein TPD52_HUMAN with the residue 173 substituted with Phosphothreonine" [UniProtKB:P55327] xref: UniProtKB:P55327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005373 ! TPD52_HUMAN [Term] id: CCO:B0071474 name: TPD52_HUMAN-Phosphoserine176 def: "Protein TPD52_HUMAN with the residue 176 substituted with Phosphoserine" [UniProtKB:P55327] xref: UniProtKB:P55327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005373 ! TPD52_HUMAN [Term] id: CCO:B0071475 name: TPD52_HUMAN-Phosphoserine223 def: "Protein TPD52_HUMAN with the residue 223 substituted with Phosphoserine" [UniProtKB:P55327] xref: UniProtKB:P55327 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005373 ! TPD52_HUMAN [Term] id: CCO:B0071476 name: TPD53_HUMAN-Phosphoserine149 def: "Protein TPD53_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q16890] xref: UniProtKB:Q16890 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0001825 ! TPD53_HUMAN [Term] id: CCO:B0071477 name: TPM1_HUMAN-N-acetylmethionine1 def: "Protein TPM1_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P09493] xref: UniProtKB:P09493 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000425 ! muscle thin filament tropomyosin relationship: located_in CCO:C0000933 ! sarcomere relationship: transformation_of CCO:B0063369 ! TPM1_HUMAN [Term] id: CCO:B0071478 name: TPM2_HUMAN-N-acetylmethionine1 def: "Protein TPM2_HUMAN with the residue 1 substituted with N-acetylmethionine" [UniProtKB:P07951] comment: By similarity xref: UniProtKB:P07951 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063362 ! TPM2_HUMAN [Term] id: CCO:B0071479 name: TPM2_HUMAN-Phosphothreonine252 def: "Protein TPM2_HUMAN with the residue 252 substituted with Phosphothreonine" [UniProtKB:P07951] comment: By similarity xref: UniProtKB:P07951 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063362 ! TPM2_HUMAN [Term] id: CCO:B0071480 name: TPM2_HUMAN-Phosphoserine283 def: "Protein TPM2_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:P07951] comment: By similarity xref: UniProtKB:P07951 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001821 ! structural constituent of muscle relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000425 ! muscle thin filament tropomyosin relationship: transformation_of CCO:B0063362 ! TPM2_HUMAN [Term] id: CCO:B0071481 name: TPM3_HUMAN-Phosphotyrosine162 def: "Protein TPM3_HUMAN with the residue 162 substituted with Phosphotyrosine" [UniProtKB:P06753] xref: UniProtKB:P06753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000323 ! actin binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000425 ! muscle thin filament tropomyosin relationship: transformation_of CCO:B0063054 ! TPM3_HUMAN [Term] id: CCO:B0071482 name: TPM3_HUMAN-Phosphothreonine252 def: "Protein TPM3_HUMAN with the residue 252 substituted with Phosphothreonine" [UniProtKB:P06753] xref: UniProtKB:P06753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063054 ! TPM3_HUMAN [Term] id: CCO:B0071483 name: TPM3_HUMAN-Phosphoserine283 def: "Protein TPM3_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:P06753] comment: By similarity xref: UniProtKB:P06753 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063054 ! TPM3_HUMAN [Term] id: CCO:B0071484 name: TPPP_HUMAN-Phosphothreonine14 def: "Protein TPPP_HUMAN with the residue 14 substituted with Phosphothreonine" [UniProtKB:O94811] xref: UniProtKB:O94811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054701 ! TPPP_HUMAN [Term] id: CCO:B0071485 name: TPPP_HUMAN-Phosphoserine18 def: "Protein TPPP_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:O94811] xref: UniProtKB:O94811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054701 ! TPPP_HUMAN [Term] id: CCO:B0071486 name: TPPP_HUMAN-Phosphoserine32 def: "Protein TPPP_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:O94811] xref: UniProtKB:O94811 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054701 ! TPPP_HUMAN [Term] id: CCO:B0071487 name: TPX2_HUMAN-Phosphothreonine59 def: "Protein TPX2_HUMAN with the residue 59 substituted with Phosphothreonine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0071488 name: TPX2_HUMAN-Phosphoserine257 def: "Protein TPX2_HUMAN with the residue 257 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0071489 name: TPX2_HUMAN-Phosphoserine310 def: "Protein TPX2_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q9ULW0] xref: UniProtKB:Q9ULW0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:B0071490 name: TR10A_HUMAN-Phosphoserine83 def: "Protein TR10A_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:O00220] xref: UniProtKB:O00220 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001360 ! death receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0002016 ! caspase activator activity relationship: has_function CCO:F0006164 ! TRAIL binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054301 ! TR10A_HUMAN [Term] id: CCO:B0071491 name: TR10A_HUMAN-Phosphoserine463 def: "Protein TR10A_HUMAN with the residue 463 substituted with Phosphoserine" [UniProtKB:O00220] xref: UniProtKB:O00220 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054301 ! TR10A_HUMAN [Term] id: CCO:B0071492 name: TR10A_HUMAN-Phosphoserine466 def: "Protein TR10A_HUMAN with the residue 466 substituted with Phosphoserine" [UniProtKB:O00220] xref: UniProtKB:O00220 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054301 ! TR10A_HUMAN [Term] id: CCO:B0071493 name: TR112_HUMAN-Phosphoserine119 def: "Protein TR112_HUMAN with the residue 119 substituted with Phosphoserine" [UniProtKB:Q9UI30] xref: UniProtKB:Q9UI30 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005568 ! TR112_HUMAN [Term] id: CCO:B0071494 name: TR150_HUMAN-Phosphoserine2 def: "Protein TR150_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071495 name: TR150_HUMAN-Phosphoserine211 def: "Protein TR150_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071496 name: TR150_HUMAN-Phosphoserine232 def: "Protein TR150_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071497 name: TR150_HUMAN-Phosphoserine237 def: "Protein TR150_HUMAN with the residue 237 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071498 name: TR150_HUMAN-Phosphoserine240 def: "Protein TR150_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071499 name: TR150_HUMAN-Phosphoserine243 def: "Protein TR150_HUMAN with the residue 243 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071500 name: TR150_HUMAN-Phosphoserine248 def: "Protein TR150_HUMAN with the residue 248 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071501 name: TR150_HUMAN-Phosphoserine253 def: "Protein TR150_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071502 name: TR150_HUMAN-Phosphoserine264 def: "Protein TR150_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071503 name: TR150_HUMAN-Phosphoserine268 def: "Protein TR150_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071504 name: TR150_HUMAN-Phosphoserine315 def: "Protein TR150_HUMAN with the residue 315 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071505 name: TR150_HUMAN-Phosphoserine320 def: "Protein TR150_HUMAN with the residue 320 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071506 name: TR150_HUMAN-Phosphothreonine324 def: "Protein TR150_HUMAN with the residue 324 substituted with Phosphothreonine" [UniProtKB:Q9Y2W1] comment: By similarity xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071507 name: TR150_HUMAN-Phosphoserine379 def: "Protein TR150_HUMAN with the residue 379 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071508 name: TR150_HUMAN-Phosphoserine406 def: "Protein TR150_HUMAN with the residue 406 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071509 name: TR150_HUMAN-Phosphoserine408 def: "Protein TR150_HUMAN with the residue 408 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071510 name: TR150_HUMAN-Phosphoserine444 def: "Protein TR150_HUMAN with the residue 444 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071511 name: TR150_HUMAN-Phosphoserine508 def: "Protein TR150_HUMAN with the residue 508 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071512 name: TR150_HUMAN-Phosphoserine534 def: "Protein TR150_HUMAN with the residue 534 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071513 name: TR150_HUMAN-Phosphoserine535 def: "Protein TR150_HUMAN with the residue 535 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071514 name: TR150_HUMAN-Phosphoserine575 def: "Protein TR150_HUMAN with the residue 575 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071515 name: TR150_HUMAN-Phosphothreonine662 def: "Protein TR150_HUMAN with the residue 662 substituted with Phosphothreonine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071516 name: TR150_HUMAN-Phosphoserine672 def: "Protein TR150_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071517 name: TR150_HUMAN-Phosphoserine682 def: "Protein TR150_HUMAN with the residue 682 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071518 name: TR150_HUMAN-Phosphoserine684 def: "Protein TR150_HUMAN with the residue 684 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] comment: By similarity xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000299 ! transcription cofactor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0005718 ! vitamin D receptor binding relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000009 ! mediator complex relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071519 name: TR150_HUMAN-Phosphoserine698 def: "Protein TR150_HUMAN with the residue 698 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071520 name: TR150_HUMAN-Phosphoserine823 def: "Protein TR150_HUMAN with the residue 823 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071521 name: TR150_HUMAN-Phosphothreonine833 def: "Protein TR150_HUMAN with the residue 833 substituted with Phosphothreonine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071522 name: TR150_HUMAN-Phosphothreonine874 def: "Protein TR150_HUMAN with the residue 874 substituted with Phosphothreonine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071523 name: TR150_HUMAN-Phosphoserine928 def: "Protein TR150_HUMAN with the residue 928 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071524 name: TR150_HUMAN-Phosphoserine939 def: "Protein TR150_HUMAN with the residue 939 substituted with Phosphoserine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071525 name: TR150_HUMAN-Phosphothreonine941 def: "Protein TR150_HUMAN with the residue 941 substituted with Phosphothreonine" [UniProtKB:Q9Y2W1] xref: UniProtKB:Q9Y2W1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:B0071526 name: TRAF4_HUMAN-Phosphoserine426 def: "Protein TRAF4_HUMAN with the residue 426 substituted with Phosphoserine" [UniProtKB:Q9BUZ4] xref: UniProtKB:Q9BUZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058525 ! TRAF4_HUMAN [Term] id: CCO:B0071527 name: TRAF7_HUMAN-Phosphoserine88 def: "Protein TRAF7_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q6Q0C0] xref: UniProtKB:Q6Q0C0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056926 ! TRAF7_HUMAN [Term] id: CCO:B0071528 name: TRAF7_HUMAN-Phosphoserine91 def: "Protein TRAF7_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q6Q0C0] xref: UniProtKB:Q6Q0C0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001656 ! GTP binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0001150 ! intrinsic to plasma membrane relationship: located_in CCO:C0001235 ! cytoplasmic vesicle relationship: transformation_of CCO:B0056926 ! TRAF7_HUMAN [Term] id: CCO:B0071529 name: TRAIP_HUMAN-Phosphoserine259 def: "Protein TRAIP_HUMAN with the residue 259 substituted with Phosphoserine" [UniProtKB:Q9BWF2] xref: UniProtKB:Q9BWF2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058532 ! TRAIP_HUMAN [Term] id: CCO:B0071530 name: TRAT1_HUMAN-Phosphotyrosine79 def: "Protein TRAT1_HUMAN with the residue 79 substituted with Phosphotyrosine" [UniProtKB:Q6PIZ9] comment: Probable xref: UniProtKB:Q6PIZ9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056916 ! TRAT1_HUMAN [Term] id: CCO:B0071531 name: TRBP2_HUMAN-Phosphoserine152 def: "Protein TRBP2_HUMAN with the residue 152 substituted with Phosphoserine" [UniProtKB:Q15633] xref: UniProtKB:Q15633 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000310 ! double-stranded RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056086 ! TRBP2_HUMAN [Term] id: CCO:B0071532 name: TREF1_HUMAN-Phosphoserine491 def: "Protein TREF1_HUMAN with the residue 491 substituted with Phosphoserine" [UniProtKB:Q96PN7] xref: UniProtKB:Q96PN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001820 ! DNA bending activity relationship: has_function CCO:F0003165 ! RNA polymerase II transcription mediator activity relationship: has_function CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058340 ! TREF1_HUMAN [Term] id: CCO:B0071533 name: TREX1_HUMAN-Phosphoserine133 def: "Protein TREX1_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:Q9NSU2] xref: UniProtKB:Q9NSU2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058923 ! TREX1_HUMAN [Term] id: CCO:B0071534 name: TREX1_HUMAN-Phosphoserine222 def: "Protein TREX1_HUMAN with the residue 222 substituted with Phosphoserine" [UniProtKB:Q9NSU2] xref: UniProtKB:Q9NSU2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000059 ! magnesium ion binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000288 ! single-stranded DNA binding relationship: has_function CCO:F0000915 ! nuclease activity relationship: has_function CCO:F0000923 ! exonuclease activity relationship: has_function CCO:F0001818 ! 3'-5'-exodeoxyribonuclease activity relationship: has_function CCO:F0001875 ! 3'-5' exonuclease activity relationship: has_function CCO:F0002192 ! exodeoxyribonuclease III activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0004985 ! MutLalpha complex binding relationship: has_function CCO:F0004987 ! MutSalpha complex binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000253 ! nuclear envelope relationship: transformation_of CCO:B0058923 ! TREX1_HUMAN [Term] id: CCO:B0071535 name: TREX1_HUMAN-Phosphoserine316 def: "Protein TREX1_HUMAN with the residue 316 substituted with Phosphoserine" [UniProtKB:Q9NSU2] xref: UniProtKB:Q9NSU2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058923 ! TREX1_HUMAN [Term] id: CCO:B0071536 name: TRFE_HUMAN-Omega-N-methylated arginine42 def: "Protein TRFE_HUMAN with the residue 42 substituted with Omega-N-methylated arginine" [UniProtKB:P02787] comment: By similarity xref: UniProtKB:P02787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0001778 ! ferric iron binding relationship: has_function CCO:F0002571 ! ferric iron transmembrane transporter activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000237 ! extracellular space relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000983 ! endocytic vesicle relationship: transformation_of CCO:B0054876 ! TRFE_HUMAN [Term] id: CCO:B0071537 name: TRFE_HUMAN-Phosphotyrosine536 def: "Protein TRFE_HUMAN with the residue 536 substituted with Phosphotyrosine" [UniProtKB:P02787] xref: UniProtKB:P02787 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054876 ! TRFE_HUMAN [Term] id: CCO:B0071538 name: TRH_HUMAN-Pyrrolidone carboxylic acid84 def: "Protein TRH_HUMAN with the residue 84 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071539 name: TRH_HUMAN-Proline amide86 def: "Protein TRH_HUMAN with the residue 86 substituted with Proline amide" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071540 name: TRH_HUMAN-Pyrrolidone carboxylic acid114 def: "Protein TRH_HUMAN with the residue 114 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071541 name: TRH_HUMAN-Proline amide116 def: "Protein TRH_HUMAN with the residue 116 substituted with Proline amide" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071542 name: TRH_HUMAN-Pyrrolidone carboxylic acid135 def: "Protein TRH_HUMAN with the residue 135 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071543 name: TRH_HUMAN-Proline amide137 def: "Protein TRH_HUMAN with the residue 137 substituted with Proline amide" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071544 name: TRH_HUMAN-Pyrrolidone carboxylic acid152 def: "Protein TRH_HUMAN with the residue 152 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071545 name: TRH_HUMAN-Proline amide154 def: "Protein TRH_HUMAN with the residue 154 substituted with Proline amide" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001901 ! thyrotropin-releasing hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000245 ! soluble fraction relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071546 name: TRH_HUMAN-Pyrrolidone carboxylic acid186 def: "Protein TRH_HUMAN with the residue 186 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071547 name: TRH_HUMAN-Proline amide188 def: "Protein TRH_HUMAN with the residue 188 substituted with Proline amide" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071548 name: TRH_HUMAN-Pyrrolidone carboxylic acid227 def: "Protein TRH_HUMAN with the residue 227 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071549 name: TRH_HUMAN-Proline amide229 def: "Protein TRH_HUMAN with the residue 229 substituted with Proline amide" [UniProtKB:P20396] comment: By similarity xref: UniProtKB:P20396 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055122 ! TRH_HUMAN [Term] id: CCO:B0071550 name: TRI16_HUMAN-Phosphoserine60 def: "Protein TRI16_HUMAN with the residue 60 substituted with Phosphoserine" [UniProtKB:O95361] xref: UniProtKB:O95361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063539 ! TRI16_HUMAN [Term] id: CCO:B0071551 name: TRI29_HUMAN-Phosphoserine21 def: "Protein TRI29_HUMAN with the residue 21 substituted with Phosphoserine" [UniProtKB:Q14134] xref: UniProtKB:Q14134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:B0071552 name: TRI29_HUMAN-Phosphothreonine476 def: "Protein TRI29_HUMAN with the residue 476 substituted with Phosphothreonine" [UniProtKB:Q14134] xref: UniProtKB:Q14134 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:B0071553 name: TRI32_HUMAN-Phosphoserine328 def: "Protein TRI32_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q13049] xref: UniProtKB:Q13049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062794 ! TRI32_HUMAN [Term] id: CCO:B0071554 name: TRI32_HUMAN-Phosphoserine335 def: "Protein TRI32_HUMAN with the residue 335 substituted with Phosphoserine" [UniProtKB:Q13049] xref: UniProtKB:Q13049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062794 ! TRI32_HUMAN [Term] id: CCO:B0071555 name: TRI32_HUMAN-Phosphoserine339 def: "Protein TRI32_HUMAN with the residue 339 substituted with Phosphoserine" [UniProtKB:Q13049] xref: UniProtKB:Q13049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062794 ! TRI32_HUMAN [Term] id: CCO:B0071556 name: TRI33_HUMAN-Phosphothreonine505 def: "Protein TRI33_HUMAN with the residue 505 substituted with Phosphothreonine" [UniProtKB:Q9UPN9] xref: UniProtKB:Q9UPN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037050 ! TRI33_HUMAN [Term] id: CCO:B0071557 name: TRI33_HUMAN-Phosphoserine862 def: "Protein TRI33_HUMAN with the residue 862 substituted with Phosphoserine" [UniProtKB:Q9UPN9] xref: UniProtKB:Q9UPN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037050 ! TRI33_HUMAN [Term] id: CCO:B0071558 name: TRI33_HUMAN-Phosphothreonine1102 def: "Protein TRI33_HUMAN with the residue 1102 substituted with Phosphothreonine" [UniProtKB:Q9UPN9] xref: UniProtKB:Q9UPN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037050 ! TRI33_HUMAN [Term] id: CCO:B0071559 name: TRI33_HUMAN-Phosphoserine1105 def: "Protein TRI33_HUMAN with the residue 1105 substituted with Phosphoserine" [UniProtKB:Q9UPN9] xref: UniProtKB:Q9UPN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037050 ! TRI33_HUMAN [Term] id: CCO:B0071560 name: TRI33_HUMAN-Phosphoserine1119 def: "Protein TRI33_HUMAN with the residue 1119 substituted with Phosphoserine" [UniProtKB:Q9UPN9] xref: UniProtKB:Q9UPN9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037050 ! TRI33_HUMAN [Term] id: CCO:B0071561 name: TRI41_HUMAN-Phosphoserine447 def: "Protein TRI41_HUMAN with the residue 447 substituted with Phosphoserine" [UniProtKB:Q8WV44] xref: UniProtKB:Q8WV44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0062904 ! TRI41_HUMAN [Term] id: CCO:B0071562 name: TRIO_HUMAN-Phosphothreonine1486 def: "Protein TRIO_HUMAN with the residue 1486 substituted with Phosphothreonine" [UniProtKB:O75962] xref: UniProtKB:O75962 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054681 ! TRIO_HUMAN [Term] id: CCO:B0071563 name: TRIO_HUMAN-Phosphothreonine1844 def: "Protein TRIO_HUMAN with the residue 1844 substituted with Phosphothreonine" [UniProtKB:O75962] xref: UniProtKB:O75962 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054681 ! TRIO_HUMAN [Term] id: CCO:B0071564 name: TRIP4_HUMAN-Phosphotyrosine289 def: "Protein TRIP4_HUMAN with the residue 289 substituted with Phosphotyrosine" [UniProtKB:Q15650] xref: UniProtKB:Q15650 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056092 ! TRIP4_HUMAN [Term] id: CCO:B0071565 name: TRIP6_HUMAN-Phosphoserine142 def: "Protein TRIP6_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q15654] xref: UniProtKB:Q15654 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:B0071566 name: TRIP6_HUMAN-Phosphoserine147 def: "Protein TRIP6_HUMAN with the residue 147 substituted with Phosphoserine" [UniProtKB:Q15654] xref: UniProtKB:Q15654 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:B0071567 name: TRIPC_HUMAN-Phosphoserine77 def: "Protein TRIPC_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071568 name: TRIPC_HUMAN-Phosphoserine85 def: "Protein TRIPC_HUMAN with the residue 85 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071569 name: TRIPC_HUMAN-Phosphoserine88 def: "Protein TRIPC_HUMAN with the residue 88 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071570 name: TRIPC_HUMAN-Phosphoserine310 def: "Protein TRIPC_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071571 name: TRIPC_HUMAN-Phosphoserine312 def: "Protein TRIPC_HUMAN with the residue 312 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071572 name: TRIPC_HUMAN-Phosphotyrosine507 def: "Protein TRIPC_HUMAN with the residue 507 substituted with Phosphotyrosine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071573 name: TRIPC_HUMAN-Phosphoserine991 def: "Protein TRIPC_HUMAN with the residue 991 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071574 name: TRIPC_HUMAN-Phosphoserine997 def: "Protein TRIPC_HUMAN with the residue 997 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006287 ! thyroid hormone receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001750 ! protein complex relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071575 name: TRIPC_HUMAN-Phosphoserine1317 def: "Protein TRIPC_HUMAN with the residue 1317 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071576 name: TRIPC_HUMAN-Phosphoserine1322 def: "Protein TRIPC_HUMAN with the residue 1322 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071577 name: TRIPC_HUMAN-Phosphoserine1427 def: "Protein TRIPC_HUMAN with the residue 1427 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071578 name: TRIPC_HUMAN-Phosphoserine1577 def: "Protein TRIPC_HUMAN with the residue 1577 substituted with Phosphoserine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071579 name: TRIPC_HUMAN-Phosphothreonine1592 def: "Protein TRIPC_HUMAN with the residue 1592 substituted with Phosphothreonine" [UniProtKB:Q14669] xref: UniProtKB:Q14669 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:B0071580 name: TRM61_HUMAN-Phosphoserine2 def: "Protein TRM61_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:Q96FX7] xref: UniProtKB:Q96FX7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063283 ! TRM61_HUMAN [Term] id: CCO:B0071581 name: TRM61_HUMAN-Phosphoserine19 def: "Protein TRM61_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q96FX7] xref: UniProtKB:Q96FX7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001755 ! methyltransferase activity relationship: has_function CCO:F0003151 ! tRNA (adenine-N1-)-methyltransferase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063283 ! TRM61_HUMAN [Term] id: CCO:B0071582 name: TRM6_HUMAN-Phosphothreonine107 def: "Protein TRM6_HUMAN with the residue 107 substituted with Phosphothreonine" [UniProtKB:Q9UJA5] xref: UniProtKB:Q9UJA5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000316 ! translation initiation factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059170 ! TRM6_HUMAN [Term] id: CCO:B0071583 name: TRPC6_HUMAN-Phosphothreonine70 def: "Protein TRPC6_HUMAN with the residue 70 substituted with Phosphothreonine" [UniProtKB:Q9Y210] xref: UniProtKB:Q9Y210 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062980 ! TRPC6_HUMAN [Term] id: CCO:B0071584 name: TRPC6_HUMAN-Phosphoserine815 def: "Protein TRPC6_HUMAN with the residue 815 substituted with Phosphoserine" [UniProtKB:Q9Y210] xref: UniProtKB:Q9Y210 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001492 ! ion channel activity relationship: has_function CCO:F0001525 ! calcium channel activity relationship: has_function CCO:F0001645 ! calcium ion binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0062980 ! TRPC6_HUMAN [Term] id: CCO:B0071585 name: TRPC6_HUMAN-Phosphoserine839 def: "Protein TRPC6_HUMAN with the residue 839 substituted with Phosphoserine" [UniProtKB:Q9Y210] xref: UniProtKB:Q9Y210 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062980 ! TRPC6_HUMAN [Term] id: CCO:B0071586 name: TRPS1_HUMAN-Phosphoserine127 def: "Protein TRPS1_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:Q9UHF7] xref: UniProtKB:Q9UHF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059138 ! TRPS1_HUMAN [Term] id: CCO:B0071587 name: TRPS1_HUMAN-Phosphoserine892 def: "Protein TRPS1_HUMAN with the residue 892 substituted with Phosphoserine" [UniProtKB:Q9UHF7] xref: UniProtKB:Q9UHF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059138 ! TRPS1_HUMAN [Term] id: CCO:B0071588 name: TRPS1_HUMAN-Phosphoserine1081 def: "Protein TRPS1_HUMAN with the residue 1081 substituted with Phosphoserine" [UniProtKB:Q9UHF7] xref: UniProtKB:Q9UHF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059138 ! TRPS1_HUMAN [Term] id: CCO:B0071589 name: TRPS1_HUMAN-Phosphoserine1085 def: "Protein TRPS1_HUMAN with the residue 1085 substituted with Phosphoserine" [UniProtKB:Q9UHF7] xref: UniProtKB:Q9UHF7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059138 ! TRPS1_HUMAN [Term] id: CCO:B0071590 name: TRXR1_HUMAN-Phosphotyrosine161 def: "Protein TRXR1_HUMAN with the residue 161 substituted with Phosphotyrosine" [UniProtKB:Q16881] xref: UniProtKB:Q16881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056179 ! TRXR1_HUMAN [Term] id: CCO:B0071591 name: TRXR1_HUMAN-Phosphotyrosine163 def: "Protein TRXR1_HUMAN with the residue 163 substituted with Phosphotyrosine" [UniProtKB:Q16881] xref: UniProtKB:Q16881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001149 ! thioredoxin-disulfide reductase activity relationship: has_function CCO:F0001897 ! selenium binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0002532 ! protein disulfide oxidoreductase activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003252 ! oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor relationship: has_function CCO:F0007986 ! FAD binding relationship: has_function CCO:F0007987 ! NADP binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0056179 ! TRXR1_HUMAN [Term] id: CCO:B0071592 name: TRXR1_HUMAN-Phosphotyrosine281 def: "Protein TRXR1_HUMAN with the residue 281 substituted with Phosphotyrosine" [UniProtKB:Q16881] xref: UniProtKB:Q16881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056179 ! TRXR1_HUMAN [Term] id: CCO:B0071593 name: TRXR1_HUMAN-Phosphotyrosine572 def: "Protein TRXR1_HUMAN with the residue 572 substituted with Phosphotyrosine" [UniProtKB:Q16881] xref: UniProtKB:Q16881 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056179 ! TRXR1_HUMAN [Term] id: CCO:B0071594 name: TS101_HUMAN-Phosphotyrosine390 def: "Protein TS101_HUMAN with the residue 390 substituted with Phosphotyrosine" [UniProtKB:Q99816] xref: UniProtKB:Q99816 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:B0071595 name: TSC1_HUMAN-Phosphoserine511 def: "Protein TSC1_HUMAN with the residue 511 substituted with Phosphoserine" [UniProtKB:Q92574] xref: UniProtKB:Q92574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002014 ! TSC1_HUMAN [Term] id: CCO:B0071596 name: TSC1_HUMAN-Phosphoserine598 def: "Protein TSC1_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:Q92574] xref: UniProtKB:Q92574 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002014 ! TSC1_HUMAN [Term] id: CCO:B0071597 name: TSC2_HUMAN-Phosphothreonine927 def: "Protein TSC2_HUMAN with the residue 927 substituted with Phosphothreonine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071598 name: TSC2_HUMAN-Phosphoserine1132 def: "Protein TSC2_HUMAN with the residue 1132 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071599 name: TSC2_HUMAN-Phosphoserine1334 def: "Protein TSC2_HUMAN with the residue 1334 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071600 name: TSC2_HUMAN-Phosphoserine1337 def: "Protein TSC2_HUMAN with the residue 1337 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001584 ! TSC1-TSC2 complex relationship: located_in CCO:C0001996 ! perinuclear region of cytoplasm relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071601 name: TSC2_HUMAN-Phosphoserine1338 def: "Protein TSC2_HUMAN with the residue 1338 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071602 name: TSC2_HUMAN-Phosphoserine1341 def: "Protein TSC2_HUMAN with the residue 1341 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071603 name: TSC2_HUMAN-Phosphoserine1449 def: "Protein TSC2_HUMAN with the residue 1449 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071604 name: TSC2_HUMAN-Phosphoserine1452 def: "Protein TSC2_HUMAN with the residue 1452 substituted with Phosphoserine" [UniProtKB:P49815] xref: UniProtKB:P49815 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001637 ! TSC2_HUMAN [Term] id: CCO:B0071605 name: TSG6_HUMAN-Phosphothreonine259 def: "Protein TSG6_HUMAN with the residue 259 substituted with Phosphothreonine" [UniProtKB:P98066] xref: UniProtKB:P98066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055666 ! TSG6_HUMAN [Term] id: CCO:B0071606 name: TSG6_HUMAN-Phosphothreonine262 def: "Protein TSG6_HUMAN with the residue 262 substituted with Phosphothreonine" [UniProtKB:P98066] xref: UniProtKB:P98066 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055666 ! TSG6_HUMAN [Term] id: CCO:B0071607 name: TSH3_HUMAN-Phosphoserine672 def: "Protein TSH3_HUMAN with the residue 672 substituted with Phosphoserine" [UniProtKB:Q63HK5] xref: UniProtKB:Q63HK5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056687 ! TSH3_HUMAN [Term] id: CCO:B0071608 name: TSNAX_HUMAN-Phosphoserine33 def: "Protein TSNAX_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:Q99598] xref: UniProtKB:Q99598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062792 ! TSNAX_HUMAN [Term] id: CCO:B0071609 name: TSNAX_HUMAN-Phosphotyrosine237 def: "Protein TSNAX_HUMAN with the residue 237 substituted with Phosphotyrosine" [UniProtKB:Q99598] comment: By similarity xref: UniProtKB:Q99598 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062792 ! TSNAX_HUMAN [Term] id: CCO:B0071610 name: TSSK4_HUMAN-Phosphothreonine197 def: "Protein TSSK4_HUMAN with the residue 197 substituted with Phosphothreonine" [UniProtKB:Q6SA08] comment: By similarity xref: UniProtKB:Q6SA08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:B0071611 name: TSSK4_HUMAN-Phosphothreonine251 def: "Protein TSSK4_HUMAN with the residue 251 substituted with Phosphothreonine" [UniProtKB:Q6SA08] xref: UniProtKB:Q6SA08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:B0071612 name: TSSK4_HUMAN-Phosphothreonine256 def: "Protein TSSK4_HUMAN with the residue 256 substituted with Phosphothreonine" [UniProtKB:Q6SA08] xref: UniProtKB:Q6SA08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:B0071613 name: TSSK4_HUMAN-Phosphoserine264 def: "Protein TSSK4_HUMAN with the residue 264 substituted with Phosphoserine" [UniProtKB:Q6SA08] xref: UniProtKB:Q6SA08 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:B0071614 name: TSYL2_HUMAN-Phosphoserine18 def: "Protein TSYL2_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q9H2G4] xref: UniProtKB:Q9H2G4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002128 ! TSYL2_HUMAN [Term] id: CCO:B0071615 name: TTC28_HUMAN-Phosphoserine1339 def: "Protein TTC28_HUMAN with the residue 1339 substituted with Phosphoserine" [UniProtKB:Q96AY4] xref: UniProtKB:Q96AY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063150 ! TTC28_HUMAN [Term] id: CCO:B0071616 name: TTC28_HUMAN-Phosphoserine1343 def: "Protein TTC28_HUMAN with the residue 1343 substituted with Phosphoserine" [UniProtKB:Q96AY4] xref: UniProtKB:Q96AY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063150 ! TTC28_HUMAN [Term] id: CCO:B0071617 name: TTC28_HUMAN-Phosphoserine1633 def: "Protein TTC28_HUMAN with the residue 1633 substituted with Phosphoserine" [UniProtKB:Q96AY4] xref: UniProtKB:Q96AY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063150 ! TTC28_HUMAN [Term] id: CCO:B0071618 name: TTC28_HUMAN-Phosphoserine1706 def: "Protein TTC28_HUMAN with the residue 1706 substituted with Phosphoserine" [UniProtKB:Q96AY4] xref: UniProtKB:Q96AY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063150 ! TTC28_HUMAN [Term] id: CCO:B0071619 name: TTF1_HUMAN-Phosphoserine65 def: "Protein TTF1_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q15361] xref: UniProtKB:Q15361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043733 ! TTF1_HUMAN [Term] id: CCO:B0071620 name: TTF1_HUMAN-Phosphoserine403 def: "Protein TTF1_HUMAN with the residue 403 substituted with Phosphoserine" [UniProtKB:Q15361] xref: UniProtKB:Q15361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043733 ! TTF1_HUMAN [Term] id: CCO:B0071621 name: TTF1_HUMAN-Phosphoserine478 def: "Protein TTF1_HUMAN with the residue 478 substituted with Phosphoserine" [UniProtKB:Q15361] xref: UniProtKB:Q15361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043733 ! TTF1_HUMAN [Term] id: CCO:B0071622 name: TTF1_HUMAN-Phosphoserine481 def: "Protein TTF1_HUMAN with the residue 481 substituted with Phosphoserine" [UniProtKB:Q15361] xref: UniProtKB:Q15361 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043733 ! TTF1_HUMAN [Term] id: CCO:B0071623 name: TTF2_HUMAN-Phosphoserine396 def: "Protein TTF2_HUMAN with the residue 396 substituted with Phosphoserine" [UniProtKB:Q9UNY4] xref: UniProtKB:Q9UNY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000304 ! RNA polymerase II transcription termination factor activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0001707 ! DNA-dependent ATPase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000523 ! transcription elongation factor complex relationship: transformation_of CCO:B0059256 ! TTF2_HUMAN [Term] id: CCO:B0071624 name: TTF2_HUMAN-Phosphoserine460 def: "Protein TTF2_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q9UNY4] xref: UniProtKB:Q9UNY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059256 ! TTF2_HUMAN [Term] id: CCO:B0071625 name: TTF2_HUMAN-Phosphoserine883 def: "Protein TTF2_HUMAN with the residue 883 substituted with Phosphoserine" [UniProtKB:Q9UNY4] xref: UniProtKB:Q9UNY4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059256 ! TTF2_HUMAN [Term] id: CCO:B0071626 name: TTHY_HUMAN-4-carboxyglutamate62 def: "Protein TTHY_HUMAN with the residue 62 substituted with 4-carboxyglutamate" [UniProtKB:P02766] comment: in a patient with Moyamoya disease; xref: UniProtKB:P02766 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063374 ! TTHY_HUMAN [Term] id: CCO:B0071627 name: TTK_HUMAN-Phosphothreonine33 def: "Protein TTK_HUMAN with the residue 33 substituted with Phosphothreonine" [UniProtKB:P33981] xref: UniProtKB:P33981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001587 ! TTK_HUMAN [Term] id: CCO:B0071628 name: TTK_HUMAN-Phosphoserine281 def: "Protein TTK_HUMAN with the residue 281 substituted with Phosphoserine" [UniProtKB:P33981] xref: UniProtKB:P33981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001587 ! TTK_HUMAN [Term] id: CCO:B0071629 name: TTK_HUMAN-Phosphoserine321 def: "Protein TTK_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:P33981] xref: UniProtKB:P33981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001587 ! TTK_HUMAN [Term] id: CCO:B0071630 name: TTK_HUMAN-Phosphoserine393 def: "Protein TTK_HUMAN with the residue 393 substituted with Phosphoserine" [UniProtKB:P33981] xref: UniProtKB:P33981 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001587 ! TTK_HUMAN [Term] id: CCO:B0071631 name: TXLNA_HUMAN-Phosphoserine18 def: "Protein TXLNA_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:P40222] xref: UniProtKB:P40222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055326 ! TXLNA_HUMAN [Term] id: CCO:B0071632 name: TXLNA_HUMAN-Phosphoserine19 def: "Protein TXLNA_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:P40222] xref: UniProtKB:P40222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001427 ! cytokine activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004417 ! high molecular weight B cell growth factor receptor binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0055326 ! TXLNA_HUMAN [Term] id: CCO:B0071633 name: TXLNA_HUMAN-Phosphoserine515 def: "Protein TXLNA_HUMAN with the residue 515 substituted with Phosphoserine" [UniProtKB:P40222] xref: UniProtKB:P40222 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055326 ! TXLNA_HUMAN [Term] id: CCO:B0071634 name: TXN4A_HUMAN-Phosphoserine132 def: "Protein TXN4A_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:P83876] xref: UniProtKB:P83876 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: transformation_of CCO:B0001702 ! TXN4A_HUMAN [Term] id: CCO:B0071635 name: TXN4B_HUMAN-Phosphoserine132 def: "Protein TXN4B_HUMAN with the residue 132 substituted with Phosphoserine" [UniProtKB:Q9NX01] xref: UniProtKB:Q9NX01 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: transformation_of CCO:B0002172 ! TXN4B_HUMAN [Term] id: CCO:B0071636 name: TXND1_HUMAN-Phosphoserine247 def: "Protein TXND1_HUMAN with the residue 247 substituted with Phosphoserine" [UniProtKB:Q9H3N1] xref: UniProtKB:Q9H3N1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058705 ! TXND1_HUMAN [Term] id: CCO:B0071637 name: TXND1_HUMAN-Phosphoserine270 def: "Protein TXND1_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q9H3N1] xref: UniProtKB:Q9H3N1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058705 ! TXND1_HUMAN [Term] id: CCO:B0071638 name: TXND1_HUMAN-Phosphoserine280 def: "Protein TXND1_HUMAN with the residue 280 substituted with Phosphoserine" [UniProtKB:Q9H3N1] xref: UniProtKB:Q9H3N1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058705 ! TXND1_HUMAN [Term] id: CCO:B0071639 name: TXNIP_HUMAN-Phosphothreonine349 def: "Protein TXNIP_HUMAN with the residue 349 substituted with Phosphothreonine" [UniProtKB:Q9H3M7] xref: UniProtKB:Q9H3M7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002133 ! TXNIP_HUMAN [Term] id: CCO:B0071640 name: TXNIP_HUMAN-Phosphoserine361 def: "Protein TXNIP_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q9H3M7] xref: UniProtKB:Q9H3M7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002133 ! TXNIP_HUMAN [Term] id: CCO:B0071641 name: TYB10_HUMAN-Phosphothreonine23 def: "Protein TYB10_HUMAN with the residue 23 substituted with Phosphothreonine" [UniProtKB:P63313] xref: UniProtKB:P63313 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0049178 ! TYB10_HUMAN [Term] id: CCO:B0071642 name: TYBN_HUMAN-N-acetylserine2 def: "Protein TYBN_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:Q99406] comment: By similarity xref: UniProtKB:Q99406 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058409 ! TYBN_HUMAN [Term] id: CCO:B0071643 name: TYOBP_HUMAN-Phosphotyrosine91 def: "Protein TYOBP_HUMAN with the residue 91 substituted with Phosphotyrosine" [UniProtKB:O43914] xref: UniProtKB:O43914 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054530 ! TYOBP_HUMAN [Term] id: CCO:B0071644 name: TYOBP_HUMAN-Phosphotyrosine102 def: "Protein TYOBP_HUMAN with the residue 102 substituted with Phosphotyrosine" [UniProtKB:O43914] comment: By similarity xref: UniProtKB:O43914 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001374 ! receptor signaling protein activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054530 ! TYOBP_HUMAN [Term] id: CCO:B0071645 name: TYRO3_HUMAN-Phosphotyrosine685 def: "Protein TYRO3_HUMAN with the residue 685 substituted with Phosphotyrosine" [UniProtKB:Q06418] comment: By similarity xref: UniProtKB:Q06418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0027493 ! TYRO3_HUMAN [Term] id: CCO:B0071646 name: TYRO3_HUMAN-Phosphotyrosine686 def: "Protein TYRO3_HUMAN with the residue 686 substituted with Phosphotyrosine" [UniProtKB:Q06418] comment: by autocatalysis; By similarity xref: UniProtKB:Q06418 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity relationship: has_function CCO:F0001082 ! receptor signaling protein tyrosine kinase activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0027493 ! TYRO3_HUMAN [Term] id: CCO:B0071647 name: U2AF1_HUMAN-N-acetylalanine2 def: "Protein U2AF1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q01081] xref: UniProtKB:Q01081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: located_in CCO:C0000750 ! Cajal body relationship: transformation_of CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:B0071648 name: U2AF1_HUMAN-Phosphoserine59 def: "Protein U2AF1_HUMAN with the residue 59 substituted with Phosphoserine" [UniProtKB:Q01081] xref: UniProtKB:Q01081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:B0071649 name: U2AF1_HUMAN-Phosphoserine195 def: "Protein U2AF1_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:Q01081] xref: UniProtKB:Q01081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:B0071650 name: U2AF1_HUMAN-Phosphoserine197 def: "Protein U2AF1_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q01081] xref: UniProtKB:Q01081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:B0071651 name: U2AF2_HUMAN-N-acetylserine2 def: "Protein U2AF2_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P26368] xref: UniProtKB:P26368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:B0071652 name: U2AF2_HUMAN-Phosphoserine2 def: "Protein U2AF2_HUMAN with the residue 2 substituted with Phosphoserine" [UniProtKB:P26368] xref: UniProtKB:P26368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:B0071653 name: U2AF2_HUMAN-Phosphoserine53 def: "Protein U2AF2_HUMAN with the residue 53 substituted with Phosphoserine" [UniProtKB:P26368] xref: UniProtKB:P26368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: transformation_of CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:B0071654 name: U2AF2_HUMAN-Phosphoserine55 def: "Protein U2AF2_HUMAN with the residue 55 substituted with Phosphoserine" [UniProtKB:P26368] xref: UniProtKB:P26368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:B0071655 name: U2AF2_HUMAN-Phosphoserine79 def: "Protein U2AF2_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:P26368] xref: UniProtKB:P26368 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:B0071656 name: U520_HUMAN-Phosphotyrosine922 def: "Protein U520_HUMAN with the residue 922 substituted with Phosphotyrosine" [UniProtKB:O75643] xref: UniProtKB:O75643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020984 ! U520_HUMAN [Term] id: CCO:B0071657 name: U520_HUMAN-Phosphotyrosine924 def: "Protein U520_HUMAN with the residue 924 substituted with Phosphotyrosine" [UniProtKB:O75643] xref: UniProtKB:O75643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020984 ! U520_HUMAN [Term] id: CCO:B0071658 name: U520_HUMAN-Phosphotyrosine926 def: "Protein U520_HUMAN with the residue 926 substituted with Phosphotyrosine" [UniProtKB:O75643] xref: UniProtKB:O75643 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0020984 ! U520_HUMAN [Term] id: CCO:B0071659 name: U5S1_HUMAN-Phosphoserine19 def: "Protein U5S1_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q15029] xref: UniProtKB:Q15029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063122 ! U5S1_HUMAN [Term] id: CCO:B0071660 name: U5S1_HUMAN-Phosphothreonine86 def: "Protein U5S1_HUMAN with the residue 86 substituted with Phosphothreonine" [UniProtKB:Q15029] xref: UniProtKB:Q15029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063122 ! U5S1_HUMAN [Term] id: CCO:B0071661 name: UACA_HUMAN-Phosphotyrosine723 def: "Protein UACA_HUMAN with the residue 723 substituted with Phosphotyrosine" [UniProtKB:Q9BZF9] xref: UniProtKB:Q9BZF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: transformation_of CCO:B0063038 ! UACA_HUMAN [Term] id: CCO:B0071662 name: UACA_HUMAN-Phosphothreonine1065 def: "Protein UACA_HUMAN with the residue 1065 substituted with Phosphothreonine" [UniProtKB:Q9BZF9] xref: UniProtKB:Q9BZF9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063038 ! UACA_HUMAN [Term] id: CCO:B0071663 name: UAP56_HUMAN-Phosphothreonine172 def: "Protein UAP56_HUMAN with the residue 172 substituted with Phosphothreonine" [UniProtKB:Q13838] xref: UniProtKB:Q13838 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0000488 ! ATP-dependent RNA helicase activity relationship: has_function CCO:F0000803 ! helicase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0001682 ! ATP-dependent helicase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000283 ! spliceosome relationship: transformation_of CCO:B0005899 ! UAP56_HUMAN [Term] id: CCO:B0071664 name: UBA1_HUMAN-Phosphoserine46 def: "Protein UBA1_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:P22314] xref: UniProtKB:P22314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063177 ! UBA1_HUMAN [Term] id: CCO:B0071665 name: UBA1_HUMAN-Phosphotyrosine55 def: "Protein UBA1_HUMAN with the residue 55 substituted with Phosphotyrosine" [UniProtKB:P22314] xref: UniProtKB:P22314 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063177 ! UBA1_HUMAN [Term] id: CCO:B0071666 name: UBC12_HUMAN-Phosphoserine50 def: "Protein UBC12_HUMAN with the residue 50 substituted with Phosphoserine" [UniProtKB:P61081] xref: UniProtKB:P61081 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0003634 ! ribosomal S6-glutamic acid ligase activity relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: transformation_of CCO:B0005329 ! UBC12_HUMAN [Term] id: CCO:B0071667 name: UBF1_HUMAN-Phosphoserine484 def: "Protein UBF1_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:P17480] xref: UniProtKB:P17480 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000290 ! RNA polymerase I transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000320 ! nucleolus relationship: transformation_of CCO:B0055088 ! UBF1_HUMAN [Term] id: CCO:B0071668 name: UBL4A_HUMAN-N6-acetyllysine48 def: "Protein UBL4A_HUMAN with the residue 48 substituted with N6-acetyllysine" [UniProtKB:P11441] xref: UniProtKB:P11441 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063099 ! UBL4A_HUMAN [Term] id: CCO:B0071669 name: UBL4A_HUMAN-N6-acetyllysine54 def: "Protein UBL4A_HUMAN with the residue 54 substituted with N6-acetyllysine" [UniProtKB:P11441] xref: UniProtKB:P11441 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0004170 ! small conjugating protein ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063099 ! UBL4A_HUMAN [Term] id: CCO:B0071670 name: UBL4A_HUMAN-Phosphoserine126 def: "Protein UBL4A_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:P11441] xref: UniProtKB:P11441 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063099 ! UBL4A_HUMAN [Term] id: CCO:B0071671 name: UBL7_HUMAN-Phosphoserine230 def: "Protein UBL7_HUMAN with the residue 230 substituted with Phosphoserine" [UniProtKB:Q96S82] xref: UniProtKB:Q96S82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062945 ! UBL7_HUMAN [Term] id: CCO:B0071672 name: UBN1_HUMAN-Phosphoserine173 def: "Protein UBN1_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q9NPG3] xref: UniProtKB:Q9NPG3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058852 ! UBN1_HUMAN [Term] id: CCO:B0071673 name: UBN1_HUMAN-Phosphoserine175 def: "Protein UBN1_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:Q9NPG3] xref: UniProtKB:Q9NPG3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058852 ! UBN1_HUMAN [Term] id: CCO:B0071674 name: UBN1_HUMAN-Phosphoserine493 def: "Protein UBN1_HUMAN with the residue 493 substituted with Phosphoserine" [UniProtKB:Q9NPG3] xref: UniProtKB:Q9NPG3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058852 ! UBN1_HUMAN [Term] id: CCO:B0071675 name: UBP11_HUMAN-Phosphoserine905 def: "Protein UBP11_HUMAN with the residue 905 substituted with Phosphoserine" [UniProtKB:P51784] xref: UniProtKB:P51784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063143 ! UBP11_HUMAN [Term] id: CCO:B0071676 name: UBP11_HUMAN-Phosphoserine910 def: "Protein UBP11_HUMAN with the residue 910 substituted with Phosphoserine" [UniProtKB:P51784] xref: UniProtKB:P51784 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063143 ! UBP11_HUMAN [Term] id: CCO:B0071677 name: UBP13_HUMAN-Phosphothreonine122 def: "Protein UBP13_HUMAN with the residue 122 substituted with Phosphothreonine" [UniProtKB:Q92995] xref: UniProtKB:Q92995 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063494 ! UBP13_HUMAN [Term] id: CCO:B0071678 name: UBP16_HUMAN-Phosphoserine415 def: "Protein UBP16_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q9Y5T5] xref: UniProtKB:Q9Y5T5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0002259 ! UBP16_HUMAN [Term] id: CCO:B0071679 name: UBP2L_HUMAN-Phosphoserine360 def: "Protein UBP2L_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071680 name: UBP2L_HUMAN-Phosphoserine416 def: "Protein UBP2L_HUMAN with the residue 416 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071681 name: UBP2L_HUMAN-Phosphothreonine419 def: "Protein UBP2L_HUMAN with the residue 419 substituted with Phosphothreonine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071682 name: UBP2L_HUMAN-Phosphoserine439 def: "Protein UBP2L_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071683 name: UBP2L_HUMAN-Phosphoserine453 def: "Protein UBP2L_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071684 name: UBP2L_HUMAN-Phosphoserine454 def: "Protein UBP2L_HUMAN with the residue 454 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071685 name: UBP2L_HUMAN-Phosphoserine467 def: "Protein UBP2L_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071686 name: UBP2L_HUMAN-Phosphoserine470 def: "Protein UBP2L_HUMAN with the residue 470 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071687 name: UBP2L_HUMAN-Phosphoserine471 def: "Protein UBP2L_HUMAN with the residue 471 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071688 name: UBP2L_HUMAN-Phosphoserine477 def: "Protein UBP2L_HUMAN with the residue 477 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071689 name: UBP2L_HUMAN-Phosphoserine605 def: "Protein UBP2L_HUMAN with the residue 605 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071690 name: UBP2L_HUMAN-Phosphoserine607 def: "Protein UBP2L_HUMAN with the residue 607 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071691 name: UBP2L_HUMAN-Phosphoserine608 def: "Protein UBP2L_HUMAN with the residue 608 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071692 name: UBP2L_HUMAN-Phosphoserine609 def: "Protein UBP2L_HUMAN with the residue 609 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071693 name: UBP2L_HUMAN-Phosphotyrosine834 def: "Protein UBP2L_HUMAN with the residue 834 substituted with Phosphotyrosine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071694 name: UBP2L_HUMAN-Phosphotyrosine835 def: "Protein UBP2L_HUMAN with the residue 835 substituted with Phosphotyrosine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071695 name: UBP2L_HUMAN-Phosphothreonine844 def: "Protein UBP2L_HUMAN with the residue 844 substituted with Phosphothreonine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071696 name: UBP2L_HUMAN-Phosphoserine852 def: "Protein UBP2L_HUMAN with the residue 852 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071697 name: UBP2L_HUMAN-Phosphoserine859 def: "Protein UBP2L_HUMAN with the residue 859 substituted with Phosphoserine" [UniProtKB:Q14157] xref: UniProtKB:Q14157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:B0071698 name: UBP33_HUMAN-Phosphoserine439 def: "Protein UBP33_HUMAN with the residue 439 substituted with Phosphoserine" [UniProtKB:Q8TEY7] xref: UniProtKB:Q8TEY7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063468 ! UBP33_HUMAN [Term] id: CCO:B0071699 name: UBP7_HUMAN-Phosphoserine963 def: "Protein UBP7_HUMAN with the residue 963 substituted with Phosphoserine" [UniProtKB:Q93009] xref: UniProtKB:Q93009 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:B0071700 name: UBP8_HUMAN-Phosphoserine452 def: "Protein UBP8_HUMAN with the residue 452 substituted with Phosphoserine" [UniProtKB:P40818] xref: UniProtKB:P40818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040082 ! UBP8_HUMAN [Term] id: CCO:B0071701 name: UBP8_HUMAN-Phosphoserine718 def: "Protein UBP8_HUMAN with the residue 718 substituted with Phosphoserine" [UniProtKB:P40818] xref: UniProtKB:P40818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040082 ! UBP8_HUMAN [Term] id: CCO:B0071702 name: UBP8_HUMAN-Phosphoserine719 def: "Protein UBP8_HUMAN with the residue 719 substituted with Phosphoserine" [UniProtKB:P40818] xref: UniProtKB:P40818 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001199 ! ubiquitin-specific protease activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0040082 ! UBP8_HUMAN [Term] id: CCO:B0071703 name: UBR5_HUMAN-Phosphoserine287 def: "Protein UBR5_HUMAN with the residue 287 substituted with Phosphoserine" [UniProtKB:O95071] xref: UniProtKB:O95071 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054719 ! UBR5_HUMAN [Term] id: CCO:B0071704 name: UBR5_HUMAN-Phosphoserine327 def: "Protein UBR5_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:O95071] xref: UniProtKB:O95071 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054719 ! UBR5_HUMAN [Term] id: CCO:B0071705 name: UBR5_HUMAN-Phosphoserine598 def: "Protein UBR5_HUMAN with the residue 598 substituted with Phosphoserine" [UniProtKB:O95071] xref: UniProtKB:O95071 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054719 ! UBR5_HUMAN [Term] id: CCO:B0071706 name: UBR5_HUMAN-Phosphoserine1549 def: "Protein UBR5_HUMAN with the residue 1549 substituted with Phosphoserine" [UniProtKB:O95071] xref: UniProtKB:O95071 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054719 ! UBR5_HUMAN [Term] id: CCO:B0071707 name: UBR5_HUMAN-Phosphotyrosine1746 def: "Protein UBR5_HUMAN with the residue 1746 substituted with Phosphotyrosine" [UniProtKB:O95071] xref: UniProtKB:O95071 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054719 ! UBR5_HUMAN [Term] id: CCO:B0071708 name: UBR5_HUMAN-Phosphoserine2071 def: "Protein UBR5_HUMAN with the residue 2071 substituted with Phosphoserine" [UniProtKB:O95071] xref: UniProtKB:O95071 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054719 ! UBR5_HUMAN [Term] id: CCO:B0071709 name: UC5IP_HUMAN-Phosphoserine16 def: "Protein UC5IP_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q99871] xref: UniProtKB:Q99871 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0004921 ! thioesterase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0063173 ! UC5IP_HUMAN [Term] id: CCO:B0071710 name: UCN1_HUMAN-Valine amide122 def: "Protein UCN1_HUMAN with the residue 122 substituted with Valine amide" [UniProtKB:P55089] comment: By similarity xref: UniProtKB:P55089 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055527 ! UCN1_HUMAN [Term] id: CCO:B0071711 name: UCN3_HUMAN-Isoleucine amide157 def: "Protein UCN3_HUMAN with the residue 157 substituted with Isoleucine amide" [UniProtKB:Q969E3] comment: Potential xref: UniProtKB:Q969E3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0058126 ! UCN3_HUMAN [Term] id: CCO:B0071712 name: UFO_HUMAN-Phosphoserine93 def: "Protein UFO_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:P30530] xref: UniProtKB:P30530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001579 ! UFO_HUMAN [Term] id: CCO:B0071713 name: UFO_HUMAN-Phosphotyrosine695 def: "Protein UFO_HUMAN with the residue 695 substituted with Phosphotyrosine" [UniProtKB:P30530] xref: UniProtKB:P30530 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001579 ! UFO_HUMAN [Term] id: CCO:B0071714 name: UGDH_HUMAN-Phosphotyrosine473 def: "Protein UGDH_HUMAN with the residue 473 substituted with Phosphotyrosine" [UniProtKB:O60701] comment: By similarity xref: UniProtKB:O60701 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0000466 ! UDP-glucose 6-dehydrogenase activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor relationship: has_function CCO:F0008078 ! NAD binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063357 ! UGDH_HUMAN [Term] id: CCO:B0071715 name: UHRF1_HUMAN-Phosphoserine76 def: "Protein UHRF1_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q96T88] xref: UniProtKB:Q96T88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002063 ! UHRF1_HUMAN [Term] id: CCO:B0071716 name: UHRF1_HUMAN-Phosphoserine91 def: "Protein UHRF1_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q96T88] xref: UniProtKB:Q96T88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002063 ! UHRF1_HUMAN [Term] id: CCO:B0071717 name: UHRF1_HUMAN-Phosphoserine707 def: "Protein UHRF1_HUMAN with the residue 707 substituted with Phosphoserine" [UniProtKB:Q96T88] xref: UniProtKB:Q96T88 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0002063 ! UHRF1_HUMAN [Term] id: CCO:B0071718 name: UHRF2_HUMAN-Phosphoserine667 def: "Protein UHRF2_HUMAN with the residue 667 substituted with Phosphoserine" [UniProtKB:Q96PU4] xref: UniProtKB:Q96PU4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0002054 ! UHRF2_HUMAN [Term] id: CCO:B0071719 name: UIMC1_HUMAN-Phosphoserine44 def: "Protein UIMC1_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071720 name: UIMC1_HUMAN-Phosphoserine46 def: "Protein UIMC1_HUMAN with the residue 46 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071721 name: UIMC1_HUMAN-Phosphoserine140 def: "Protein UIMC1_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071722 name: UIMC1_HUMAN-Phosphoserine402 def: "Protein UIMC1_HUMAN with the residue 402 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071723 name: UIMC1_HUMAN-Phosphoserine415 def: "Protein UIMC1_HUMAN with the residue 415 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071724 name: UIMC1_HUMAN-Phosphoserine419 def: "Protein UIMC1_HUMAN with the residue 419 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071725 name: UIMC1_HUMAN-Phosphoserine597 def: "Protein UIMC1_HUMAN with the residue 597 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071726 name: UIMC1_HUMAN-Phosphoserine627 def: "Protein UIMC1_HUMAN with the residue 627 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071727 name: UIMC1_HUMAN-Phosphoserine653 def: "Protein UIMC1_HUMAN with the residue 653 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071728 name: UIMC1_HUMAN-Phosphoserine677 def: "Protein UIMC1_HUMAN with the residue 677 substituted with Phosphoserine" [UniProtKB:Q96RL1] xref: UniProtKB:Q96RL1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058381 ! UIMC1_HUMAN [Term] id: CCO:B0071729 name: ULK1_HUMAN-Phosphoserine556 def: "Protein ULK1_HUMAN with the residue 556 substituted with Phosphoserine" [UniProtKB:O75385] xref: UniProtKB:O75385 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054628 ! ULK1_HUMAN [Term] id: CCO:B0071730 name: ULK1_HUMAN-Phosphothreonine625 def: "Protein ULK1_HUMAN with the residue 625 substituted with Phosphothreonine" [UniProtKB:O75385] comment: By similarity xref: UniProtKB:O75385 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000358 ! autophagic vacuole relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001024 ! cytoplasmic vesicle membrane relationship: located_in CCO:C0001707 ! neuron projection relationship: transformation_of CCO:B0054628 ! ULK1_HUMAN [Term] id: CCO:B0071731 name: ULK1_HUMAN-Phosphoserine638 def: "Protein ULK1_HUMAN with the residue 638 substituted with Phosphoserine" [UniProtKB:O75385] xref: UniProtKB:O75385 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054628 ! ULK1_HUMAN [Term] id: CCO:B0071732 name: UN13A_HUMAN-Phosphoserine245 def: "Protein UN13A_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:Q9UPW8] comment: By similarity xref: UniProtKB:Q9UPW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0059271 ! UN13A_HUMAN [Term] id: CCO:B0071733 name: UN13B_HUMAN-Phosphothreonine605 def: "Protein UN13B_HUMAN with the residue 605 substituted with Phosphothreonine" [UniProtKB:O14795] xref: UniProtKB:O14795 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001900 ! synapse relationship: transformation_of CCO:B0054377 ! UN13B_HUMAN [Term] id: CCO:B0071734 name: UNC5C_HUMAN-Phosphotyrosine568 def: "Protein UNC5C_HUMAN with the residue 568 substituted with Phosphotyrosine" [UniProtKB:O95185] comment: By similarity xref: UniProtKB:O95185 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001363 ! netrin receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054733 ! UNC5C_HUMAN [Term] id: CCO:B0071735 name: UNC5D_HUMAN-Phosphothreonine210 def: "Protein UNC5D_HUMAN with the residue 210 substituted with Phosphothreonine" [UniProtKB:Q6UXZ4] xref: UniProtKB:Q6UXZ4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0056957 ! UNC5D_HUMAN [Term] id: CCO:B0071736 name: UNK_HUMAN-Phosphoserine378 def: "Protein UNK_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:Q9C0B0] xref: UniProtKB:Q9C0B0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025523 ! UNK_HUMAN [Term] id: CCO:B0071737 name: UNK_HUMAN-Phosphoserine385 def: "Protein UNK_HUMAN with the residue 385 substituted with Phosphoserine" [UniProtKB:Q9C0B0] xref: UniProtKB:Q9C0B0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025523 ! UNK_HUMAN [Term] id: CCO:B0071738 name: UNK_HUMAN-Phosphotyrosine412 def: "Protein UNK_HUMAN with the residue 412 substituted with Phosphotyrosine" [UniProtKB:Q9C0B0] xref: UniProtKB:Q9C0B0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0025523 ! UNK_HUMAN [Term] id: CCO:B0071739 name: UROK_HUMAN-Phosphoserine158 def: "Protein UROK_HUMAN with the residue 158 substituted with Phosphoserine" [UniProtKB:P00749] xref: UniProtKB:P00749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054827 ! UROK_HUMAN [Term] id: CCO:B0071740 name: UROK_HUMAN-Phosphoserine323 def: "Protein UROK_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:P00749] xref: UniProtKB:P00749 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054827 ! UROK_HUMAN [Term] id: CCO:B0071741 name: US6NL_HUMAN-Phosphoserine391 def: "Protein US6NL_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001401 ! GTPase activator activity relationship: has_function CCO:F0001402 ! Rab GTPase activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071742 name: US6NL_HUMAN-Phosphoserine396 def: "Protein US6NL_HUMAN with the residue 396 substituted with Phosphoserine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071743 name: US6NL_HUMAN-Phosphoserine546 def: "Protein US6NL_HUMAN with the residue 546 substituted with Phosphoserine" [UniProtKB:Q92738] comment: By similarity xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071744 name: US6NL_HUMAN-Phosphotyrosine582 def: "Protein US6NL_HUMAN with the residue 582 substituted with Phosphotyrosine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071745 name: US6NL_HUMAN-Phosphoserine585 def: "Protein US6NL_HUMAN with the residue 585 substituted with Phosphoserine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071746 name: US6NL_HUMAN-Phosphoserine617 def: "Protein US6NL_HUMAN with the residue 617 substituted with Phosphoserine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071747 name: US6NL_HUMAN-Phosphoserine673 def: "Protein US6NL_HUMAN with the residue 673 substituted with Phosphoserine" [UniProtKB:Q92738] comment: By similarity xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071748 name: US6NL_HUMAN-Phosphoserine680 def: "Protein US6NL_HUMAN with the residue 680 substituted with Phosphoserine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071749 name: US6NL_HUMAN-Phosphotyrosine710 def: "Protein US6NL_HUMAN with the residue 710 substituted with Phosphotyrosine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071750 name: US6NL_HUMAN-Phosphoserine716 def: "Protein US6NL_HUMAN with the residue 716 substituted with Phosphoserine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071751 name: US6NL_HUMAN-Phosphotyrosine729 def: "Protein US6NL_HUMAN with the residue 729 substituted with Phosphotyrosine" [UniProtKB:Q92738] xref: UniProtKB:Q92738 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058086 ! US6NL_HUMAN [Term] id: CCO:B0071752 name: USF2_HUMAN-Phosphothreonine293 def: "Protein USF2_HUMAN with the residue 293 substituted with Phosphothreonine" [UniProtKB:Q15853] xref: UniProtKB:Q15853 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000291 ! RNA polymerase II transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0005853 ! bHLH transcription factor binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056117 ! USF2_HUMAN [Term] id: CCO:B0071753 name: USH2A_HUMAN-Phosphothreonine1290 def: "Protein USH2A_HUMAN with the residue 1290 substituted with Phosphothreonine" [UniProtKB:O75445] xref: UniProtKB:O75445 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054636 ! USH2A_HUMAN [Term] id: CCO:B0071754 name: USH2A_HUMAN-Phosphoserine1424 def: "Protein USH2A_HUMAN with the residue 1424 substituted with Phosphoserine" [UniProtKB:O75445] xref: UniProtKB:O75445 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054636 ! USH2A_HUMAN [Term] id: CCO:B0071755 name: USO1_HUMAN-Phosphoserine942 def: "Protein USO1_HUMAN with the residue 942 substituted with Phosphoserine" [UniProtKB:O60763] xref: UniProtKB:O60763 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063073 ! USO1_HUMAN [Term] id: CCO:B0071756 name: USP9X_HUMAN-Phosphoserine1593 def: "Protein USP9X_HUMAN with the residue 1593 substituted with Phosphoserine" [UniProtKB:Q93008] xref: UniProtKB:Q93008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:B0071757 name: USP9X_HUMAN-Phosphotyrosine1808 def: "Protein USP9X_HUMAN with the residue 1808 substituted with Phosphotyrosine" [UniProtKB:Q93008] comment: By similarity xref: UniProtKB:Q93008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:B0071758 name: USP9X_HUMAN-Phosphoserine2436 def: "Protein USP9X_HUMAN with the residue 2436 substituted with Phosphoserine" [UniProtKB:Q93008] xref: UniProtKB:Q93008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:B0071759 name: USP9X_HUMAN-Phosphotyrosine2533 def: "Protein USP9X_HUMAN with the residue 2533 substituted with Phosphotyrosine" [UniProtKB:Q93008] xref: UniProtKB:Q93008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000666 ! cysteine-type endopeptidase activity relationship: has_function CCO:F0000675 ! ubiquitin thiolesterase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001783 ! peptidase activity relationship: has_function CCO:F0001784 ! cysteine-type peptidase activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:B0071760 name: USP9X_HUMAN-Phosphoserine2540 def: "Protein USP9X_HUMAN with the residue 2540 substituted with Phosphoserine" [UniProtKB:Q93008] xref: UniProtKB:Q93008 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:B0071761 name: UT14A_HUMAN-Phosphoserine52 def: "Protein UT14A_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0071762 name: UT14A_HUMAN-Phosphoserine77 def: "Protein UT14A_HUMAN with the residue 77 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0071763 name: UT14A_HUMAN-Phosphoserine405 def: "Protein UT14A_HUMAN with the residue 405 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0071764 name: UT14A_HUMAN-Phosphoserine407 def: "Protein UT14A_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:Q9BVJ6] xref: UniProtKB:Q9BVJ6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:B0071765 name: UTP11_HUMAN-Phosphotyrosine50 def: "Protein UTP11_HUMAN with the residue 50 substituted with Phosphotyrosine" [UniProtKB:Q9Y3A2] xref: UniProtKB:Q9Y3A2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059334 ! UTP11_HUMAN [Term] id: CCO:B0071766 name: UTP18_HUMAN-Phosphothreonine204 def: "Protein UTP18_HUMAN with the residue 204 substituted with Phosphothreonine" [UniProtKB:Q9Y5J1] xref: UniProtKB:Q9Y5J1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:B0071767 name: UTP20_HUMAN-Phosphoserine788 def: "Protein UTP20_HUMAN with the residue 788 substituted with Phosphoserine" [UniProtKB:O75691] xref: UniProtKB:O75691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000322 ! small nucleolar ribonucleoprotein complex relationship: transformation_of CCO:B0054662 ! UTP20_HUMAN [Term] id: CCO:B0071768 name: UTP20_HUMAN-Phosphothreonine1741 def: "Protein UTP20_HUMAN with the residue 1741 substituted with Phosphothreonine" [UniProtKB:O75691] xref: UniProtKB:O75691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054662 ! UTP20_HUMAN [Term] id: CCO:B0071769 name: UTP20_HUMAN-Phosphothreonine2064 def: "Protein UTP20_HUMAN with the residue 2064 substituted with Phosphothreonine" [UniProtKB:O75691] xref: UniProtKB:O75691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054662 ! UTP20_HUMAN [Term] id: CCO:B0071770 name: UTP20_HUMAN-Phosphoserine2637 def: "Protein UTP20_HUMAN with the residue 2637 substituted with Phosphoserine" [UniProtKB:O75691] xref: UniProtKB:O75691 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054662 ! UTP20_HUMAN [Term] id: CCO:B0071771 name: V1AR_HUMAN-Phosphoserine404 def: "Protein V1AR_HUMAN with the residue 404 substituted with Phosphoserine" [UniProtKB:P37288] comment: By similarity xref: UniProtKB:P37288 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055318 ! V1AR_HUMAN [Term] id: CCO:B0071772 name: VA0D1_HUMAN-Phosphotyrosine270 def: "Protein VA0D1_HUMAN with the residue 270 substituted with Phosphotyrosine" [UniProtKB:P61421] comment: By similarity xref: UniProtKB:P61421 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001990 ! hydrogen-exporting ATPase activity, phosphorylative mechanism relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: located_in CCO:C0000793 ! vacuolar proton-transporting V-type ATPase complex relationship: transformation_of CCO:B0063214 ! VA0D1_HUMAN [Term] id: CCO:B0071773 name: VA0D1_HUMAN-Phosphoserine283 def: "Protein VA0D1_HUMAN with the residue 283 substituted with Phosphoserine" [UniProtKB:P61421] comment: By similarity xref: UniProtKB:P61421 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063214 ! VA0D1_HUMAN [Term] id: CCO:B0071774 name: VAPB_HUMAN-Phosphoserine159 def: "Protein VAPB_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:O95292] xref: UniProtKB:O95292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001484 ! structural molecule activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004208 ! enzyme binding relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_function CCO:F0007341 ! beta-tubulin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000375 ! Golgi apparatus relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000733 ! endomembrane system relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0054746 ! VAPB_HUMAN [Term] id: CCO:B0071775 name: VAPB_HUMAN-Phosphoserine160 def: "Protein VAPB_HUMAN with the residue 160 substituted with Phosphoserine" [UniProtKB:O95292] xref: UniProtKB:O95292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054746 ! VAPB_HUMAN [Term] id: CCO:B0071776 name: VAPB_HUMAN-Phosphoserine206 def: "Protein VAPB_HUMAN with the residue 206 substituted with Phosphoserine" [UniProtKB:O95292] xref: UniProtKB:O95292 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054746 ! VAPB_HUMAN [Term] id: CCO:B0071777 name: VASP_HUMAN-N-acetylserine2 def: "Protein VASP_HUMAN with the residue 2 substituted with N-acetylserine" [UniProtKB:P50552] xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071778 name: VASP_HUMAN-Phosphotyrosine39 def: "Protein VASP_HUMAN with the residue 39 substituted with Phosphotyrosine" [UniProtKB:P50552] xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071779 name: VASP_HUMAN-Phosphoserine157 def: "Protein VASP_HUMAN with the residue 157 substituted with Phosphoserine" [UniProtKB:P50552] comment: by PKA, PKC, PKG and ROCK1; xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071780 name: VASP_HUMAN-Phosphoserine239 def: "Protein VASP_HUMAN with the residue 239 substituted with Phosphoserine" [UniProtKB:P50552] comment: by PKA and PKG; xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071781 name: VASP_HUMAN-Phosphothreonine278 def: "Protein VASP_HUMAN with the residue 278 substituted with Phosphothreonine" [UniProtKB:P50552] comment: by PKA and PKG; xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071782 name: VASP_HUMAN-Phosphothreonine316 def: "Protein VASP_HUMAN with the residue 316 substituted with Phosphothreonine" [UniProtKB:P50552] xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071783 name: VASP_HUMAN-Phosphoserine322 def: "Protein VASP_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:P50552] xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071784 name: VASP_HUMAN-Phosphoserine323 def: "Protein VASP_HUMAN with the residue 323 substituted with Phosphoserine" [UniProtKB:P50552] comment: By similarity xref: UniProtKB:P50552 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:B0071785 name: VATC1_HUMAN-N-acetylthreonine2 def: "Protein VATC1_HUMAN with the residue 2 substituted with N-acetylthreonine" [UniProtKB:P21283] xref: UniProtKB:P21283 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001491 ! transporter activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0002559 ! hydrogen ion transmembrane transporter activity relationship: has_function CCO:F0003359 ! hydrolase activity relationship: has_function CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances relationship: has_function CCO:F0006283 ! hydrogen ion transporting ATPase activity, rotational mechanism relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000792 ! proton-transporting two-sector ATPase complex relationship: transformation_of CCO:B0063235 ! VATC1_HUMAN [Term] id: CCO:B0071786 name: VATE1_HUMAN-Phosphotyrosine56 def: "Protein VATE1_HUMAN with the residue 56 substituted with Phosphotyrosine" [UniProtKB:P36543] xref: UniProtKB:P36543 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0021842 ! VATE1_HUMAN [Term] id: CCO:B0071787 name: VAV2_HUMAN-Phosphotyrosine142 def: "Protein VAV2_HUMAN with the residue 142 substituted with Phosphotyrosine" [UniProtKB:P52735] comment: by EGFR; xref: UniProtKB:P52735 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055489 ! VAV2_HUMAN [Term] id: CCO:B0071788 name: VAV2_HUMAN-Phosphotyrosine159 def: "Protein VAV2_HUMAN with the residue 159 substituted with Phosphotyrosine" [UniProtKB:P52735] comment: by EGFR; xref: UniProtKB:P52735 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055489 ! VAV2_HUMAN [Term] id: CCO:B0071789 name: VAV2_HUMAN-Phosphotyrosine172 def: "Protein VAV2_HUMAN with the residue 172 substituted with Phosphotyrosine" [UniProtKB:P52735] comment: by EGFR; xref: UniProtKB:P52735 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001456 ! epidermal growth factor receptor binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000444 ! plasma membrane relationship: transformation_of CCO:B0055489 ! VAV2_HUMAN [Term] id: CCO:B0071790 name: VAV_HUMAN-Phosphotyrosine826 def: "Protein VAV_HUMAN with the residue 826 substituted with Phosphotyrosine" [UniProtKB:P15498] xref: UniProtKB:P15498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001390 ! guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0004248 ! diacylglycerol binding relationship: has_function CCO:F0004518 ! Rac guanyl-nucleotide exchange factor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:B0071791 name: VAV_HUMAN-Phosphotyrosine844 def: "Protein VAV_HUMAN with the residue 844 substituted with Phosphotyrosine" [UniProtKB:P15498] comment: By similarity xref: UniProtKB:P15498 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:B0071792 name: VGFR1_HUMAN-Phosphotyrosine1048 def: "Protein VGFR1_HUMAN with the residue 1048 substituted with Phosphotyrosine" [UniProtKB:P17948] xref: UniProtKB:P17948 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:B0071793 name: VGFR2_HUMAN-Phosphotyrosine1054 def: "Protein VGFR2_HUMAN with the residue 1054 substituted with Phosphotyrosine" [UniProtKB:P35968] xref: UniProtKB:P35968 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055305 ! VGFR2_HUMAN [Term] id: CCO:B0071794 name: VGFR2_HUMAN-Phosphotyrosine1059 def: "Protein VGFR2_HUMAN with the residue 1059 substituted with Phosphotyrosine" [UniProtKB:P35968] comment: by autocatalysis; xref: UniProtKB:P35968 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055305 ! VGFR2_HUMAN [Term] id: CCO:B0071795 name: VGFR3_HUMAN-Phosphotyrosine1063 def: "Protein VGFR3_HUMAN with the residue 1063 substituted with Phosphotyrosine" [UniProtKB:P35916] xref: UniProtKB:P35916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055304 ! VGFR3_HUMAN [Term] id: CCO:B0071796 name: VGFR3_HUMAN-Phosphotyrosine1068 def: "Protein VGFR3_HUMAN with the residue 1068 substituted with Phosphotyrosine" [UniProtKB:P35916] comment: by autocatalysis; By similarity xref: UniProtKB:P35916 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055304 ! VGFR3_HUMAN [Term] id: CCO:B0071797 name: VGLL4_HUMAN-Phosphoserine52 def: "Protein VGLL4_HUMAN with the residue 52 substituted with Phosphoserine" [UniProtKB:Q14135] xref: UniProtKB:Q14135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055960 ! VGLL4_HUMAN [Term] id: CCO:B0071798 name: VGLL4_HUMAN-Phosphoserine149 def: "Protein VGLL4_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q14135] xref: UniProtKB:Q14135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055960 ! VGLL4_HUMAN [Term] id: CCO:B0071799 name: VGLL4_HUMAN-Phosphothreonine153 def: "Protein VGLL4_HUMAN with the residue 153 substituted with Phosphothreonine" [UniProtKB:Q14135] xref: UniProtKB:Q14135 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055960 ! VGLL4_HUMAN [Term] id: CCO:B0071800 name: VIME_HUMAN-Phosphotyrosine38 def: "Protein VIME_HUMAN with the residue 38 substituted with Phosphotyrosine" [UniProtKB:P08670] xref: UniProtKB:P08670 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:B0071801 name: VINC_HUMAN-Phosphotyrosine692 def: "Protein VINC_HUMAN with the residue 692 substituted with Phosphotyrosine" [UniProtKB:P18206] xref: UniProtKB:P18206 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:B0071802 name: VINEX_HUMAN-Phosphoserine348 def: "Protein VINEX_HUMAN with the residue 348 substituted with Phosphoserine" [UniProtKB:O60504] xref: UniProtKB:O60504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054564 ! VINEX_HUMAN [Term] id: CCO:B0071803 name: VINEX_HUMAN-Phosphothreonine529 def: "Protein VINEX_HUMAN with the residue 529 substituted with Phosphothreonine" [UniProtKB:O60504] xref: UniProtKB:O60504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001486 ! structural constituent of cytoskeleton relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003605 ! vinculin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000477 ! focal adhesion relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0054564 ! VINEX_HUMAN [Term] id: CCO:B0071804 name: VINEX_HUMAN-Phosphoserine530 def: "Protein VINEX_HUMAN with the residue 530 substituted with Phosphoserine" [UniProtKB:O60504] xref: UniProtKB:O60504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054564 ! VINEX_HUMAN [Term] id: CCO:B0071805 name: VINEX_HUMAN-Phosphoserine545 def: "Protein VINEX_HUMAN with the residue 545 substituted with Phosphoserine" [UniProtKB:O60504] xref: UniProtKB:O60504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054564 ! VINEX_HUMAN [Term] id: CCO:B0071806 name: VINEX_HUMAN-Phosphoserine551 def: "Protein VINEX_HUMAN with the residue 551 substituted with Phosphoserine" [UniProtKB:O60504] xref: UniProtKB:O60504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054564 ! VINEX_HUMAN [Term] id: CCO:B0071807 name: VINEX_HUMAN-Phosphoserine563 def: "Protein VINEX_HUMAN with the residue 563 substituted with Phosphoserine" [UniProtKB:O60504] xref: UniProtKB:O60504 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054564 ! VINEX_HUMAN [Term] id: CCO:B0071808 name: VIPR1_HUMAN-Phosphoserine449 def: "Protein VIPR1_HUMAN with the residue 449 substituted with Phosphoserine" [UniProtKB:P32241] comment: By similarity xref: UniProtKB:P32241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001225 ! signal transducer activity relationship: has_function CCO:F0001226 ! receptor activity relationship: has_function CCO:F0001272 ! G-protein coupled receptor activity relationship: has_function CCO:F0001337 ! vasoactive intestinal polypeptide receptor activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0055253 ! VIPR1_HUMAN [Term] id: CCO:B0071809 name: VIPR1_HUMAN-Phosphoserine455 def: "Protein VIPR1_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:P32241] comment: By similarity xref: UniProtKB:P32241 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055253 ! VIPR1_HUMAN [Term] id: CCO:B0071810 name: VIP_HUMAN-Methionine amide107 def: "Protein VIP_HUMAN with the residue 107 substituted with Methionine amide" [UniProtKB:P01282] xref: UniProtKB:P01282 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001479 ! hormone activity relationship: has_function CCO:F0001481 ! neuropeptide hormone activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: transformation_of CCO:B0054849 ! VIP_HUMAN [Term] id: CCO:B0071811 name: VIP_HUMAN-Asparagine amide152 def: "Protein VIP_HUMAN with the residue 152 substituted with Asparagine amide" [UniProtKB:P01282] xref: UniProtKB:P01282 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054849 ! VIP_HUMAN [Term] id: CCO:B0071812 name: VKIND_HUMAN-Phosphoserine982 def: "Protein VKIND_HUMAN with the residue 982 substituted with Phosphoserine" [UniProtKB:Q76NI1] comment: By similarity xref: UniProtKB:Q76NI1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057109 ! VKIND_HUMAN [Term] id: CCO:B0071813 name: VPP2_HUMAN-Phosphoserine177 def: "Protein VPP2_HUMAN with the residue 177 substituted with Phosphoserine" [UniProtKB:Q9Y487] xref: UniProtKB:Q9Y487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063303 ! VPP2_HUMAN [Term] id: CCO:B0071814 name: VPP2_HUMAN-Phosphoserine695 def: "Protein VPP2_HUMAN with the residue 695 substituted with Phosphoserine" [UniProtKB:Q9Y487] xref: UniProtKB:Q9Y487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063303 ! VPP2_HUMAN [Term] id: CCO:B0071815 name: VPP2_HUMAN-Phosphoserine700 def: "Protein VPP2_HUMAN with the residue 700 substituted with Phosphoserine" [UniProtKB:Q9Y487] xref: UniProtKB:Q9Y487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063303 ! VPP2_HUMAN [Term] id: CCO:B0071816 name: VPP2_HUMAN-Phosphoserine704 def: "Protein VPP2_HUMAN with the residue 704 substituted with Phosphoserine" [UniProtKB:Q9Y487] xref: UniProtKB:Q9Y487 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063303 ! VPP2_HUMAN [Term] id: CCO:B0071817 name: VPS35_HUMAN-Phosphoserine7 def: "Protein VPS35_HUMAN with the residue 7 substituted with Phosphoserine" [UniProtKB:Q96QK1] comment: By similarity xref: UniProtKB:Q96QK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063258 ! VPS35_HUMAN [Term] id: CCO:B0071818 name: VPS35_HUMAN-Phosphotyrosine791 def: "Protein VPS35_HUMAN with the residue 791 substituted with Phosphotyrosine" [UniProtKB:Q96QK1] comment: By similarity xref: UniProtKB:Q96QK1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063258 ! VPS35_HUMAN [Term] id: CCO:B0071819 name: VSX2_HUMAN-N6-acetyllysine11 def: "Protein VSX2_HUMAN with the residue 11 substituted with N6-acetyllysine" [UniProtKB:P58304] comment: By similarity xref: UniProtKB:P58304 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055569 ! VSX2_HUMAN [Term] id: CCO:B0071820 name: VTA1_HUMAN-N-acetylalanine2 def: "Protein VTA1_HUMAN with the residue 2 substituted with N-acetylalanine" [UniProtKB:Q9NP79] xref: UniProtKB:Q9NP79 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005259 ! VTA1_HUMAN [Term] id: CCO:B0071821 name: WAPL_HUMAN-Phosphoserine380 def: "Protein WAPL_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0071822 name: WAPL_HUMAN-Phosphoserine904 def: "Protein WAPL_HUMAN with the residue 904 substituted with Phosphoserine" [UniProtKB:Q7Z5K2] xref: UniProtKB:Q7Z5K2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:B0071823 name: WASF2_HUMAN-Phosphoserine482 def: "Protein WASF2_HUMAN with the residue 482 substituted with Phosphoserine" [UniProtKB:Q9Y6W5] xref: UniProtKB:Q9Y6W5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000323 ! actin binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000753 ! actin cytoskeleton relationship: located_in CCO:C0000935 ! lamellipodium relationship: located_in CCO:C0001706 ! cell projection relationship: transformation_of CCO:B0059418 ! WASF2_HUMAN [Term] id: CCO:B0071824 name: WASF2_HUMAN-Phosphoserine484 def: "Protein WASF2_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:Q9Y6W5] xref: UniProtKB:Q9Y6W5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059418 ! WASF2_HUMAN [Term] id: CCO:B0071825 name: WASF2_HUMAN-Phosphoserine488 def: "Protein WASF2_HUMAN with the residue 488 substituted with Phosphoserine" [UniProtKB:Q9Y6W5] xref: UniProtKB:Q9Y6W5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059418 ! WASF2_HUMAN [Term] id: CCO:B0071826 name: WASF2_HUMAN-Phosphoserine489 def: "Protein WASF2_HUMAN with the residue 489 substituted with Phosphoserine" [UniProtKB:Q9Y6W5] xref: UniProtKB:Q9Y6W5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059418 ! WASF2_HUMAN [Term] id: CCO:B0071827 name: WASP_HUMAN-Phosphotyrosine291 def: "Protein WASP_HUMAN with the residue 291 substituted with Phosphotyrosine" [UniProtKB:P42768] xref: UniProtKB:P42768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:B0071828 name: WASP_HUMAN-Phosphoserine483 def: "Protein WASP_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:P42768] comment: by CK2; xref: UniProtKB:P42768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:B0071829 name: WASP_HUMAN-Phosphoserine484 def: "Protein WASP_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:P42768] comment: by CK2; xref: UniProtKB:P42768 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:B0071830 name: WBP11_HUMAN-Phosphothreonine328 def: "Protein WBP11_HUMAN with the residue 328 substituted with Phosphothreonine" [UniProtKB:Q9Y2W2] xref: UniProtKB:Q9Y2W2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005313 ! WBP11_HUMAN [Term] id: CCO:B0071831 name: WBS14_HUMAN-Phosphoserine23 def: "Protein WBS14_HUMAN with the residue 23 substituted with Phosphoserine" [UniProtKB:Q9NP71] comment: By similarity xref: UniProtKB:Q9NP71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058835 ! WBS14_HUMAN [Term] id: CCO:B0071832 name: WBS14_HUMAN-Phosphoserine25 def: "Protein WBS14_HUMAN with the residue 25 substituted with Phosphoserine" [UniProtKB:Q9NP71] comment: By similarity xref: UniProtKB:Q9NP71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058835 ! WBS14_HUMAN [Term] id: CCO:B0071833 name: WBS14_HUMAN-Phosphothreonine509 def: "Protein WBS14_HUMAN with the residue 509 substituted with Phosphothreonine" [UniProtKB:Q9NP71] comment: By similarity xref: UniProtKB:Q9NP71 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001738 ! transcription factor binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_function CCO:F0006299 ! protein heterodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058835 ! WBS14_HUMAN [Term] id: CCO:B0071834 name: WD51B_HUMAN-Phosphoserine321 def: "Protein WD51B_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:Q8TC44] xref: UniProtKB:Q8TC44 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005998 ! WD51B_HUMAN [Term] id: CCO:B0071835 name: WDR33_HUMAN-Phosphoserine1210 def: "Protein WDR33_HUMAN with the residue 1210 substituted with Phosphoserine" [UniProtKB:Q9C0J8] xref: UniProtKB:Q9C0J8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:B0071836 name: WDR3_HUMAN-Phosphoserine240 def: "Protein WDR3_HUMAN with the residue 240 substituted with Phosphoserine" [UniProtKB:Q9UNX4] xref: UniProtKB:Q9UNX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063540 ! WDR3_HUMAN [Term] id: CCO:B0071837 name: WDR3_HUMAN-Phosphoserine241 def: "Protein WDR3_HUMAN with the residue 241 substituted with Phosphoserine" [UniProtKB:Q9UNX4] xref: UniProtKB:Q9UNX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063540 ! WDR3_HUMAN [Term] id: CCO:B0071838 name: WDR3_HUMAN-Phosphotyrosine723 def: "Protein WDR3_HUMAN with the residue 723 substituted with Phosphotyrosine" [UniProtKB:Q9UNX4] xref: UniProtKB:Q9UNX4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0002175 ! small-subunit processome relationship: transformation_of CCO:B0063540 ! WDR3_HUMAN [Term] id: CCO:B0071839 name: WDR74_HUMAN-Phosphoserine361 def: "Protein WDR74_HUMAN with the residue 361 substituted with Phosphoserine" [UniProtKB:Q6RFH5] xref: UniProtKB:Q6RFH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0006296 ! WDR74_HUMAN [Term] id: CCO:B0071840 name: WDR89_HUMAN-Phosphoserine67 def: "Protein WDR89_HUMAN with the residue 67 substituted with Phosphoserine" [UniProtKB:Q96FK6] xref: UniProtKB:Q96FK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063482 ! WDR89_HUMAN [Term] id: CCO:B0071841 name: WDR89_HUMAN-Phosphotyrosine69 def: "Protein WDR89_HUMAN with the residue 69 substituted with Phosphotyrosine" [UniProtKB:Q96FK6] xref: UniProtKB:Q96FK6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063482 ! WDR89_HUMAN [Term] id: CCO:B0071842 name: WFS1_HUMAN-Phosphoserine32 def: "Protein WFS1_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:O76024] comment: By similarity xref: UniProtKB:O76024 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0008060 ! ATPase binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000364 ! endoplasmic reticulum relationship: located_in CCO:C0000370 ! endoplasmic reticulum membrane relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000767 ! integral to membrane relationship: located_in CCO:C0000990 ! integral to endoplasmic reticulum membrane relationship: located_in CCO:C0001005 ! dendrite relationship: transformation_of CCO:B0054687 ! WFS1_HUMAN [Term] id: CCO:B0071843 name: WIPF1_HUMAN-Phosphoserine350 def: "Protein WIPF1_HUMAN with the residue 350 substituted with Phosphoserine" [UniProtKB:O43516] xref: UniProtKB:O43516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063008 ! WIPF1_HUMAN [Term] id: CCO:B0071844 name: WNK1_HUMAN-Phosphoserine19 def: "Protein WNK1_HUMAN with the residue 19 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071845 name: WNK1_HUMAN-Phosphoserine167 def: "Protein WNK1_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071846 name: WNK1_HUMAN-Phosphoserine174 def: "Protein WNK1_HUMAN with the residue 174 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071847 name: WNK1_HUMAN-Phosphoserine378 def: "Protein WNK1_HUMAN with the residue 378 substituted with Phosphoserine" [UniProtKB:Q9H4A3] comment: by autocatalysis; By similarity xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071848 name: WNK1_HUMAN-Phosphoserine382 def: "Protein WNK1_HUMAN with the residue 382 substituted with Phosphoserine" [UniProtKB:Q9H4A3] comment: by autocatalysis; By similarity xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071849 name: WNK1_HUMAN-Phosphoserine1261 def: "Protein WNK1_HUMAN with the residue 1261 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071850 name: WNK1_HUMAN-Phosphoserine1297 def: "Protein WNK1_HUMAN with the residue 1297 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071851 name: WNK1_HUMAN-Phosphoserine1300 def: "Protein WNK1_HUMAN with the residue 1300 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071852 name: WNK1_HUMAN-Phosphoserine1978 def: "Protein WNK1_HUMAN with the residue 1978 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071853 name: WNK1_HUMAN-Phosphoserine2002 def: "Protein WNK1_HUMAN with the residue 2002 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071854 name: WNK1_HUMAN-Phosphoserine2011 def: "Protein WNK1_HUMAN with the residue 2011 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071855 name: WNK1_HUMAN-Phosphoserine2012 def: "Protein WNK1_HUMAN with the residue 2012 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071856 name: WNK1_HUMAN-Phosphoserine2027 def: "Protein WNK1_HUMAN with the residue 2027 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071857 name: WNK1_HUMAN-Phosphoserine2029 def: "Protein WNK1_HUMAN with the residue 2029 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071858 name: WNK1_HUMAN-Phosphoserine2032 def: "Protein WNK1_HUMAN with the residue 2032 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071859 name: WNK1_HUMAN-Phosphoserine2038 def: "Protein WNK1_HUMAN with the residue 2038 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071860 name: WNK1_HUMAN-Phosphoserine2121 def: "Protein WNK1_HUMAN with the residue 2121 substituted with Phosphoserine" [UniProtKB:Q9H4A3] xref: UniProtKB:Q9H4A3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001216 ! protein kinase inhibitor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058713 ! WNK1_HUMAN [Term] id: CCO:B0071861 name: WNK2_HUMAN-Phosphoserine352 def: "Protein WNK2_HUMAN with the residue 352 substituted with Phosphoserine" [UniProtKB:Q9Y3S1] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y3S1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059344 ! WNK2_HUMAN [Term] id: CCO:B0071862 name: WNK2_HUMAN-Phosphoserine356 def: "Protein WNK2_HUMAN with the residue 356 substituted with Phosphoserine" [UniProtKB:Q9Y3S1] comment: by autocatalysis; By similarity xref: UniProtKB:Q9Y3S1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059344 ! WNK2_HUMAN [Term] id: CCO:B0071863 name: WNK2_HUMAN-Phosphoserine1817 def: "Protein WNK2_HUMAN with the residue 1817 substituted with Phosphoserine" [UniProtKB:Q9Y3S1] xref: UniProtKB:Q9Y3S1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059344 ! WNK2_HUMAN [Term] id: CCO:B0071864 name: WNK2_HUMAN-Phosphoserine1818 def: "Protein WNK2_HUMAN with the residue 1818 substituted with Phosphoserine" [UniProtKB:Q9Y3S1] xref: UniProtKB:Q9Y3S1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059344 ! WNK2_HUMAN [Term] id: CCO:B0071865 name: WNK3_HUMAN-Phosphoserine304 def: "Protein WNK3_HUMAN with the residue 304 substituted with Phosphoserine" [UniProtKB:Q9BYP7] comment: by autocatalysis; By similarity xref: UniProtKB:Q9BYP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058581 ! WNK3_HUMAN [Term] id: CCO:B0071866 name: WNK3_HUMAN-Phosphoserine308 def: "Protein WNK3_HUMAN with the residue 308 substituted with Phosphoserine" [UniProtKB:Q9BYP7] comment: by autocatalysis; By similarity xref: UniProtKB:Q9BYP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058581 ! WNK3_HUMAN [Term] id: CCO:B0071867 name: WNK3_HUMAN-Phosphoserine734 def: "Protein WNK3_HUMAN with the residue 734 substituted with Phosphoserine" [UniProtKB:Q9BYP7] xref: UniProtKB:Q9BYP7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001045 ! protein serine/threonine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058581 ! WNK3_HUMAN [Term] id: CCO:B0071868 name: WRIP1_HUMAN-Phosphoserine65 def: "Protein WRIP1_HUMAN with the residue 65 substituted with Phosphoserine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071869 name: WRIP1_HUMAN-Phosphoserine75 def: "Protein WRIP1_HUMAN with the residue 75 substituted with Phosphoserine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071870 name: WRIP1_HUMAN-Phosphothreonine85 def: "Protein WRIP1_HUMAN with the residue 85 substituted with Phosphothreonine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071871 name: WRIP1_HUMAN-Phosphoserine91 def: "Protein WRIP1_HUMAN with the residue 91 substituted with Phosphoserine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071872 name: WRIP1_HUMAN-Phosphoserine92 def: "Protein WRIP1_HUMAN with the residue 92 substituted with Phosphoserine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071873 name: WRIP1_HUMAN-Phosphothreonine116 def: "Protein WRIP1_HUMAN with the residue 116 substituted with Phosphothreonine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071874 name: WRIP1_HUMAN-Phosphoserine153 def: "Protein WRIP1_HUMAN with the residue 153 substituted with Phosphoserine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071875 name: WRIP1_HUMAN-Phosphotyrosine534 def: "Protein WRIP1_HUMAN with the residue 534 substituted with Phosphotyrosine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071876 name: WRIP1_HUMAN-Phosphotyrosine562 def: "Protein WRIP1_HUMAN with the residue 562 substituted with Phosphotyrosine" [UniProtKB:Q96S55] xref: UniProtKB:Q96S55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:B0071877 name: WRN_HUMAN-Phosphoserine453 def: "Protein WRN_HUMAN with the residue 453 substituted with Phosphoserine" [UniProtKB:Q14191] xref: UniProtKB:Q14191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:B0071878 name: WRN_HUMAN-Phosphoserine467 def: "Protein WRN_HUMAN with the residue 467 substituted with Phosphoserine" [UniProtKB:Q14191] xref: UniProtKB:Q14191 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:B0071879 name: WWC1_HUMAN-Phosphothreonine912 def: "Protein WWC1_HUMAN with the residue 912 substituted with Phosphothreonine" [UniProtKB:Q8IX03] xref: UniProtKB:Q8IX03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:B0071880 name: WWC1_HUMAN-Phosphothreonine929 def: "Protein WWC1_HUMAN with the residue 929 substituted with Phosphothreonine" [UniProtKB:Q8IX03] xref: UniProtKB:Q8IX03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:B0071881 name: WWC1_HUMAN-Phosphoserine931 def: "Protein WWC1_HUMAN with the residue 931 substituted with Phosphoserine" [UniProtKB:Q8IX03] xref: UniProtKB:Q8IX03 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:B0071882 name: WWP1_HUMAN-Phosphothreonine822 def: "Protein WWP1_HUMAN with the residue 822 substituted with Phosphothreonine" [UniProtKB:Q9H0M0] xref: UniProtKB:Q9H0M0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058653 ! WWP1_HUMAN [Term] id: CCO:B0071883 name: WWP2_HUMAN-Phosphoserine211 def: "Protein WWP2_HUMAN with the residue 211 substituted with Phosphoserine" [UniProtKB:O00308] xref: UniProtKB:O00308 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001198 ! ubiquitin-protein ligase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000026 ! ubiquitin ligase complex relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0062807 ! WWP2_HUMAN [Term] id: CCO:B0071884 name: WWTR1_HUMAN-Phosphoserine87 def: "Protein WWTR1_HUMAN with the residue 87 substituted with Phosphoserine" [UniProtKB:Q9GZV5] xref: UniProtKB:Q9GZV5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058638 ! WWTR1_HUMAN [Term] id: CCO:B0071885 name: WWTR1_HUMAN-Phosphoserine89 def: "Protein WWTR1_HUMAN with the residue 89 substituted with Phosphoserine" [UniProtKB:Q9GZV5] comment: By similarity xref: UniProtKB:Q9GZV5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0004454 ! transcription regulator activity relationship: has_function CCO:F0005714 ! protein homodimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0058638 ! WWTR1_HUMAN [Term] id: CCO:B0071886 name: WWTR1_HUMAN-Phosphoserine93 def: "Protein WWTR1_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q9GZV5] comment: By similarity xref: UniProtKB:Q9GZV5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058638 ! WWTR1_HUMAN [Term] id: CCO:B0071887 name: WWTR1_HUMAN-Phosphoserine105 def: "Protein WWTR1_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q9GZV5] xref: UniProtKB:Q9GZV5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058638 ! WWTR1_HUMAN [Term] id: CCO:B0071888 name: XDH_HUMAN-Phosphothreonine222 def: "Protein XDH_HUMAN with the residue 222 substituted with Phosphothreonine" [UniProtKB:P47989] xref: UniProtKB:P47989 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000343 ! catalytic activity relationship: has_function CCO:F0001210 ! xanthine dehydrogenase activity relationship: has_function CCO:F0001211 ! xanthine oxidase activity relationship: has_function CCO:F0001643 ! iron ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0003172 ! oxidoreductase activity relationship: has_function CCO:F0004329 ! molybdenum ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0007986 ! FAD binding relationship: has_function CCO:F0008138 ! iron-sulfur cluster binding relationship: has_function CCO:F0008139 ! 2 iron, 2 sulfur cluster binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000359 ! peroxisome relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0055396 ! XDH_HUMAN [Term] id: CCO:B0071889 name: XPC_HUMAN-Phosphothreonine169 def: "Protein XPC_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0071890 name: XPC_HUMAN-Phosphoserine891 def: "Protein XPC_HUMAN with the residue 891 substituted with Phosphoserine" [UniProtKB:Q01831] xref: UniProtKB:Q01831 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0001714 ! XPC_HUMAN [Term] id: CCO:B0071891 name: XPO7_HUMAN-Phosphotyrosine58 def: "Protein XPO7_HUMAN with the residue 58 substituted with Phosphotyrosine" [UniProtKB:Q9UIA9] xref: UniProtKB:Q9UIA9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001369 ! nuclear export signal receptor activity relationship: has_function CCO:F0001633 ! binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000260 ! nuclear pore relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0005665 ! XPO7_HUMAN [Term] id: CCO:B0071892 name: XPR1_HUMAN-Phosphoserine666 def: "Protein XPR1_HUMAN with the residue 666 substituted with Phosphoserine" [UniProtKB:Q9UBH6] xref: UniProtKB:Q9UBH6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059074 ! XPR1_HUMAN [Term] id: CCO:B0071893 name: XPR1_HUMAN-Phosphoserine668 def: "Protein XPR1_HUMAN with the residue 668 substituted with Phosphoserine" [UniProtKB:Q9UBH6] xref: UniProtKB:Q9UBH6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059074 ! XPR1_HUMAN [Term] id: CCO:B0071894 name: XPR1_HUMAN-Phosphothreonine690 def: "Protein XPR1_HUMAN with the residue 690 substituted with Phosphothreonine" [UniProtKB:Q9UBH6] xref: UniProtKB:Q9UBH6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059074 ! XPR1_HUMAN [Term] id: CCO:B0071895 name: XRCC4_HUMAN-Phosphoserine327 def: "Protein XRCC4_HUMAN with the residue 327 substituted with Phosphoserine" [UniProtKB:Q13426] xref: UniProtKB:Q13426 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001681 ! protein C-terminus binding relationship: has_function CCO:F0003433 ! ligase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000120 ! condensed chromosome relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0000506 ! DNA-dependent protein kinase complex relationship: located_in CCO:C0001480 ! DNA ligase IV complex relationship: transformation_of CCO:B0005651 ! XRCC4_HUMAN [Term] id: CCO:B0071896 name: XRCC4_HUMAN-Phosphoserine328 def: "Protein XRCC4_HUMAN with the residue 328 substituted with Phosphoserine" [UniProtKB:Q13426] xref: UniProtKB:Q13426 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005651 ! XRCC4_HUMAN [Term] id: CCO:B0071897 name: XRN2_HUMAN-Phosphothreonine439 def: "Protein XRN2_HUMAN with the residue 439 substituted with Phosphothreonine" [UniProtKB:Q9H0D6] xref: UniProtKB:Q9H0D6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:B0071898 name: XTP3A_HUMAN-Phosphoserine138 def: "Protein XTP3A_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:Q9H773] xref: UniProtKB:Q9H773 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062949 ! XTP3A_HUMAN [Term] id: CCO:B0071899 name: YA043_HUMAN-Phosphoserine14 def: "Protein YA043_HUMAN with the residue 14 substituted with Phosphoserine" [UniProtKB:Q7L0L9] xref: UniProtKB:Q7L0L9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000767 ! integral to membrane relationship: transformation_of CCO:B0057112 ! YA043_HUMAN [Term] id: CCO:B0071900 name: YAF2_HUMAN-Phosphoserine6 def: "Protein YAF2_HUMAN with the residue 6 substituted with Phosphoserine" [UniProtKB:Q8IY57] xref: UniProtKB:Q8IY57 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057384 ! YAF2_HUMAN [Term] id: CCO:B0071901 name: YAF2_HUMAN-Phosphoserine149 def: "Protein YAF2_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:Q8IY57] xref: UniProtKB:Q8IY57 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057384 ! YAF2_HUMAN [Term] id: CCO:B0071902 name: YAF2_HUMAN-Phosphoserine167 def: "Protein YAF2_HUMAN with the residue 167 substituted with Phosphoserine" [UniProtKB:Q8IY57] xref: UniProtKB:Q8IY57 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057384 ! YAF2_HUMAN [Term] id: CCO:B0071903 name: YAP1_HUMAN-Phosphoserine61 def: "Protein YAP1_HUMAN with the residue 61 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071904 name: YAP1_HUMAN-Phosphoserine109 def: "Protein YAP1_HUMAN with the residue 109 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071905 name: YAP1_HUMAN-Phosphothreonine110 def: "Protein YAP1_HUMAN with the residue 110 substituted with Phosphothreonine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071906 name: YAP1_HUMAN-Phosphoserine127 def: "Protein YAP1_HUMAN with the residue 127 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071907 name: YAP1_HUMAN-Phosphoserine128 def: "Protein YAP1_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071908 name: YAP1_HUMAN-Phosphoserine131 def: "Protein YAP1_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071909 name: YAP1_HUMAN-Phosphoserine138 def: "Protein YAP1_HUMAN with the residue 138 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071910 name: YAP1_HUMAN-Phosphothreonine143 def: "Protein YAP1_HUMAN with the residue 143 substituted with Phosphothreonine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071911 name: YAP1_HUMAN-Phosphoserine149 def: "Protein YAP1_HUMAN with the residue 149 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071912 name: YAP1_HUMAN-Phosphothreonine154 def: "Protein YAP1_HUMAN with the residue 154 substituted with Phosphothreonine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071913 name: YAP1_HUMAN-Phosphoserine236 def: "Protein YAP1_HUMAN with the residue 236 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000272 ! transcription factor complex relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071914 name: YAP1_HUMAN-Phosphoserine238 def: "Protein YAP1_HUMAN with the residue 238 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071915 name: YAP1_HUMAN-Phosphoserine251 def: "Protein YAP1_HUMAN with the residue 251 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071916 name: YAP1_HUMAN-Phosphoserine317 def: "Protein YAP1_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071917 name: YAP1_HUMAN-Phosphoserine321 def: "Protein YAP1_HUMAN with the residue 321 substituted with Phosphoserine" [UniProtKB:P46937] xref: UniProtKB:P46937 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055381 ! YAP1_HUMAN [Term] id: CCO:B0071918 name: YB056_HUMAN-Phosphoserine40 def: "Protein YB056_HUMAN with the residue 40 substituted with Phosphoserine" [UniProtKB:Q9BSF0] comment: By similarity xref: UniProtKB:Q9BSF0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062813 ! YB056_HUMAN [Term] id: CCO:B0071919 name: YES_HUMAN-Phosphotyrosine32 def: "Protein YES_HUMAN with the residue 32 substituted with Phosphotyrosine" [UniProtKB:P07947] xref: UniProtKB:P07947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005465 ! YES_HUMAN [Term] id: CCO:B0071920 name: YES_HUMAN-Phosphotyrosine223 def: "Protein YES_HUMAN with the residue 223 substituted with Phosphotyrosine" [UniProtKB:P07947] xref: UniProtKB:P07947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005465 ! YES_HUMAN [Term] id: CCO:B0071921 name: YES_HUMAN-Phosphotyrosine446 def: "Protein YES_HUMAN with the residue 446 substituted with Phosphotyrosine" [UniProtKB:P07947] xref: UniProtKB:P07947 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005465 ! YES_HUMAN [Term] id: CCO:B0071922 name: YETS2_HUMAN-Phosphoserine118 def: "Protein YETS2_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q9ULM3] xref: UniProtKB:Q9ULM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059230 ! YETS2_HUMAN [Term] id: CCO:B0071923 name: YETS2_HUMAN-Phosphoserine144 def: "Protein YETS2_HUMAN with the residue 144 substituted with Phosphoserine" [UniProtKB:Q9ULM3] xref: UniProtKB:Q9ULM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059230 ! YETS2_HUMAN [Term] id: CCO:B0071924 name: YETS2_HUMAN-Phosphoserine447 def: "Protein YETS2_HUMAN with the residue 447 substituted with Phosphoserine" [UniProtKB:Q9ULM3] xref: UniProtKB:Q9ULM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059230 ! YETS2_HUMAN [Term] id: CCO:B0071925 name: YETS2_HUMAN-Phosphoserine465 def: "Protein YETS2_HUMAN with the residue 465 substituted with Phosphoserine" [UniProtKB:Q9ULM3] xref: UniProtKB:Q9ULM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059230 ! YETS2_HUMAN [Term] id: CCO:B0071926 name: YETS2_HUMAN-Phosphoserine519 def: "Protein YETS2_HUMAN with the residue 519 substituted with Phosphoserine" [UniProtKB:Q9ULM3] xref: UniProtKB:Q9ULM3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059230 ! YETS2_HUMAN [Term] id: CCO:B0071927 name: YK021_HUMAN-Phosphoserine424 def: "Protein YK021_HUMAN with the residue 424 substituted with Phosphoserine" [UniProtKB:Q96M56] xref: UniProtKB:Q96M56 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058280 ! YK021_HUMAN [Term] id: CCO:B0071928 name: YLPM1_HUMAN-Phosphoserine634 def: "Protein YLPM1_HUMAN with the residue 634 substituted with Phosphoserine" [UniProtKB:P49750] xref: UniProtKB:P49750 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0063400 ! YLPM1_HUMAN [Term] id: CCO:B0071929 name: YLPM1_HUMAN-Phosphoserine924 def: "Protein YLPM1_HUMAN with the residue 924 substituted with Phosphoserine" [UniProtKB:P49750] xref: UniProtKB:P49750 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063400 ! YLPM1_HUMAN [Term] id: CCO:B0071930 name: YYAP1_HUMAN-Phosphoserine724 def: "Protein YYAP1_HUMAN with the residue 724 substituted with Phosphoserine" [UniProtKB:Q9H869] xref: UniProtKB:Q9H869 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: transformation_of CCO:B0063012 ! YYAP1_HUMAN [Term] id: CCO:B0071931 name: Z280B_HUMAN-Phosphoserine105 def: "Protein Z280B_HUMAN with the residue 105 substituted with Phosphoserine" [UniProtKB:Q86YH2] xref: UniProtKB:Q86YH2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057304 ! Z280B_HUMAN [Term] id: CCO:B0071932 name: Z280C_HUMAN-Phosphoserine76 def: "Protein Z280C_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q8ND82] xref: UniProtKB:Q8ND82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057575 ! Z280C_HUMAN [Term] id: CCO:B0071933 name: Z280C_HUMAN-Phosphoserine80 def: "Protein Z280C_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q8ND82] xref: UniProtKB:Q8ND82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057575 ! Z280C_HUMAN [Term] id: CCO:B0071934 name: Z280C_HUMAN-Phosphoserine115 def: "Protein Z280C_HUMAN with the residue 115 substituted with Phosphoserine" [UniProtKB:Q8ND82] xref: UniProtKB:Q8ND82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057575 ! Z280C_HUMAN [Term] id: CCO:B0071935 name: Z280C_HUMAN-Phosphoserine118 def: "Protein Z280C_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q8ND82] xref: UniProtKB:Q8ND82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057575 ! Z280C_HUMAN [Term] id: CCO:B0071936 name: Z280C_HUMAN-Phosphothreonine540 def: "Protein Z280C_HUMAN with the residue 540 substituted with Phosphothreonine" [UniProtKB:Q8ND82] xref: UniProtKB:Q8ND82 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057575 ! Z280C_HUMAN [Term] id: CCO:B0071937 name: Z280D_HUMAN-Phosphoserine530 def: "Protein Z280D_HUMAN with the residue 530 substituted with Phosphoserine" [UniProtKB:Q6N043] xref: UniProtKB:Q6N043 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056846 ! Z280D_HUMAN [Term] id: CCO:B0071938 name: Z280D_HUMAN-Phosphoserine545 def: "Protein Z280D_HUMAN with the residue 545 substituted with Phosphoserine" [UniProtKB:Q6N043] xref: UniProtKB:Q6N043 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056846 ! Z280D_HUMAN [Term] id: CCO:B0071939 name: Z324A_HUMAN-Phosphoserine131 def: "Protein Z324A_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:O75467] xref: UniProtKB:O75467 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054638 ! Z324A_HUMAN [Term] id: CCO:B0071940 name: Z3H7B_HUMAN-Phosphotyrosine664 def: "Protein Z3H7B_HUMAN with the residue 664 substituted with Phosphotyrosine" [UniProtKB:Q9UGR2] xref: UniProtKB:Q9UGR2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0029451 ! Z3H7B_HUMAN [Term] id: CCO:B0071941 name: Z512B_HUMAN-Phosphoserine409 def: "Protein Z512B_HUMAN with the residue 409 substituted with Phosphoserine" [UniProtKB:Q96KM6] xref: UniProtKB:Q96KM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058260 ! Z512B_HUMAN [Term] id: CCO:B0071942 name: Z512B_HUMAN-Phosphoserine686 def: "Protein Z512B_HUMAN with the residue 686 substituted with Phosphoserine" [UniProtKB:Q96KM6] xref: UniProtKB:Q96KM6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058260 ! Z512B_HUMAN [Term] id: CCO:B0071943 name: Z518A_HUMAN-Phosphoserine31 def: "Protein Z518A_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:Q6AHZ1] xref: UniProtKB:Q6AHZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056715 ! Z518A_HUMAN [Term] id: CCO:B0071944 name: Z518A_HUMAN-Phosphoserine655 def: "Protein Z518A_HUMAN with the residue 655 substituted with Phosphoserine" [UniProtKB:Q6AHZ1] xref: UniProtKB:Q6AHZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056715 ! Z518A_HUMAN [Term] id: CCO:B0071945 name: Z585A_HUMAN-Phosphoserine118 def: "Protein Z585A_HUMAN with the residue 118 substituted with Phosphoserine" [UniProtKB:Q6P3V2] xref: UniProtKB:Q6P3V2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056888 ! Z585A_HUMAN [Term] id: CCO:B0071946 name: ZA2G_HUMAN-Pyrrolidone carboxylic acid18 def: "Protein ZA2G_HUMAN with the residue 18 substituted with Pyrrolidone carboxylic acid" [UniProtKB:P25311] xref: UniProtKB:P25311 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000934 ! ribonuclease activity relationship: has_function CCO:F0001642 ! fatty acid binding relationship: has_function CCO:F0001832 ! protein transmembrane transporter activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000201 ! extracellular region relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001669 ! MHC class I protein complex relationship: transformation_of CCO:B0055183 ! ZA2G_HUMAN [Term] id: CCO:B0071947 name: ZAP70_HUMAN-Phosphotyrosine248 def: "Protein ZAP70_HUMAN with the residue 248 substituted with Phosphotyrosine" [UniProtKB:P43403] xref: UniProtKB:P43403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:B0071948 name: ZAP70_HUMAN-Phosphoserine289 def: "Protein ZAP70_HUMAN with the residue 289 substituted with Phosphoserine" [UniProtKB:P43403] xref: UniProtKB:P43403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:B0071949 name: ZAP70_HUMAN-Phosphotyrosine292 def: "Protein ZAP70_HUMAN with the residue 292 substituted with Phosphotyrosine" [UniProtKB:P43403] xref: UniProtKB:P43403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:B0071950 name: ZAP70_HUMAN-Phosphotyrosine315 def: "Protein ZAP70_HUMAN with the residue 315 substituted with Phosphotyrosine" [UniProtKB:P43403] xref: UniProtKB:P43403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000031 ! nucleotide binding relationship: has_function CCO:F0001043 ! protein kinase activity relationship: has_function CCO:F0001081 ! non-membrane spanning protein tyrosine kinase activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001655 ! ATP binding relationship: has_function CCO:F0003114 ! kinase activity relationship: has_function CCO:F0003316 ! transferase activity relationship: has_function CCO:F0008374 ! protein tyrosine kinase activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000397 ! cytosol relationship: located_in CCO:C0001630 ! T cell receptor complex relationship: transformation_of CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:B0071951 name: ZAP70_HUMAN-Phosphotyrosine319 def: "Protein ZAP70_HUMAN with the residue 319 substituted with Phosphotyrosine" [UniProtKB:P43403] xref: UniProtKB:P43403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:B0071952 name: ZAP70_HUMAN-Phosphotyrosine492 def: "Protein ZAP70_HUMAN with the residue 492 substituted with Phosphotyrosine" [UniProtKB:P43403] comment: by autocatalysis; xref: UniProtKB:P43403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:B0071953 name: ZAP70_HUMAN-Phosphotyrosine493 def: "Protein ZAP70_HUMAN with the residue 493 substituted with Phosphotyrosine" [UniProtKB:P43403] xref: UniProtKB:P43403 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:B0071954 name: ZBT10_HUMAN-Phosphoserine210 def: "Protein ZBT10_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:Q96DT7] xref: UniProtKB:Q96DT7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058198 ! ZBT10_HUMAN [Term] id: CCO:B0071955 name: ZBT10_HUMAN-Phosphoserine565 def: "Protein ZBT10_HUMAN with the residue 565 substituted with Phosphoserine" [UniProtKB:Q96DT7] xref: UniProtKB:Q96DT7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058198 ! ZBT10_HUMAN [Term] id: CCO:B0071956 name: ZBT10_HUMAN-Phosphoserine647 def: "Protein ZBT10_HUMAN with the residue 647 substituted with Phosphoserine" [UniProtKB:Q96DT7] xref: UniProtKB:Q96DT7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058198 ! ZBT10_HUMAN [Term] id: CCO:B0071957 name: ZBT10_HUMAN-Phosphothreonine721 def: "Protein ZBT10_HUMAN with the residue 721 substituted with Phosphothreonine" [UniProtKB:Q96DT7] xref: UniProtKB:Q96DT7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058198 ! ZBT10_HUMAN [Term] id: CCO:B0071958 name: ZBT12_HUMAN-Phosphothreonine19 def: "Protein ZBT12_HUMAN with the residue 19 substituted with Phosphothreonine" [UniProtKB:Q9Y330] xref: UniProtKB:Q9Y330 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059329 ! ZBT12_HUMAN [Term] id: CCO:B0071959 name: ZBT16_HUMAN-Phosphoserine76 def: "Protein ZBT16_HUMAN with the residue 76 substituted with Phosphoserine" [UniProtKB:Q05516] comment: by PDPK; Potential xref: UniProtKB:Q05516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:B0071960 name: ZBT16_HUMAN-Phosphoserine184 def: "Protein ZBT16_HUMAN with the residue 184 substituted with Phosphoserine" [UniProtKB:Q05516] comment: by PDPK; Potential xref: UniProtKB:Q05516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:B0071961 name: ZBT16_HUMAN-Phosphoserine197 def: "Protein ZBT16_HUMAN with the residue 197 substituted with Phosphoserine" [UniProtKB:Q05516] comment: by PDPK; Potential xref: UniProtKB:Q05516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:B0071962 name: ZBT16_HUMAN-Phosphoserine256 def: "Protein ZBT16_HUMAN with the residue 256 substituted with Phosphoserine" [UniProtKB:Q05516] comment: by PDPK; Potential xref: UniProtKB:Q05516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:B0071963 name: ZBT16_HUMAN-Phosphothreonine282 def: "Protein ZBT16_HUMAN with the residue 282 substituted with Phosphothreonine" [UniProtKB:Q05516] comment: by PDPK; Potential xref: UniProtKB:Q05516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:B0071964 name: ZBT16_HUMAN-Phosphoserine628 def: "Protein ZBT16_HUMAN with the residue 628 substituted with Phosphoserine" [UniProtKB:Q05516] comment: by PDPK; Potential xref: UniProtKB:Q05516 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:B0071965 name: ZBT20_HUMAN-Phosphoserine432 def: "Protein ZBT20_HUMAN with the residue 432 substituted with Phosphoserine" [UniProtKB:Q9HC78] comment: By similarity xref: UniProtKB:Q9HC78 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058799 ! ZBT20_HUMAN [Term] id: CCO:B0071966 name: ZBT38_HUMAN-Phosphoserine130 def: "Protein ZBT38_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q8NAP3] xref: UniProtKB:Q8NAP3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057549 ! ZBT38_HUMAN [Term] id: CCO:B0071967 name: ZBT38_HUMAN-Phosphoserine309 def: "Protein ZBT38_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:Q8NAP3] xref: UniProtKB:Q8NAP3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057549 ! ZBT38_HUMAN [Term] id: CCO:B0071968 name: ZBT40_HUMAN-Phosphothreonine337 def: "Protein ZBT40_HUMAN with the residue 337 substituted with Phosphothreonine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0071969 name: ZBT40_HUMAN-Phosphothreonine412 def: "Protein ZBT40_HUMAN with the residue 412 substituted with Phosphothreonine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0071970 name: ZBT40_HUMAN-Phosphothreonine416 def: "Protein ZBT40_HUMAN with the residue 416 substituted with Phosphothreonine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0071971 name: ZBT40_HUMAN-Phosphothreonine418 def: "Protein ZBT40_HUMAN with the residue 418 substituted with Phosphothreonine" [UniProtKB:Q9NUA8] xref: UniProtKB:Q9NUA8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037805 ! ZBT40_HUMAN [Term] id: CCO:B0071972 name: ZBT44_HUMAN-Phosphoserine135 def: "Protein ZBT44_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q8NCP5] xref: UniProtKB:Q8NCP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057572 ! ZBT44_HUMAN [Term] id: CCO:B0071973 name: ZBT44_HUMAN-Phosphoserine161 def: "Protein ZBT44_HUMAN with the residue 161 substituted with Phosphoserine" [UniProtKB:Q8NCP5] xref: UniProtKB:Q8NCP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057572 ! ZBT44_HUMAN [Term] id: CCO:B0071974 name: ZBT44_HUMAN-Phosphoserine191 def: "Protein ZBT44_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q8NCP5] comment: By similarity xref: UniProtKB:Q8NCP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057572 ! ZBT44_HUMAN [Term] id: CCO:B0071975 name: ZBT44_HUMAN-Phosphoserine194 def: "Protein ZBT44_HUMAN with the residue 194 substituted with Phosphoserine" [UniProtKB:Q8NCP5] comment: By similarity xref: UniProtKB:Q8NCP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057572 ! ZBT44_HUMAN [Term] id: CCO:B0071976 name: ZBT7A_HUMAN-Phosphoserine337 def: "Protein ZBT7A_HUMAN with the residue 337 substituted with Phosphoserine" [UniProtKB:O95365] xref: UniProtKB:O95365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054751 ! ZBT7A_HUMAN [Term] id: CCO:B0071977 name: ZBT7A_HUMAN-Phosphoserine341 def: "Protein ZBT7A_HUMAN with the residue 341 substituted with Phosphoserine" [UniProtKB:O95365] comment: By similarity xref: UniProtKB:O95365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005559 ! histone acetyltransferase binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054751 ! ZBT7A_HUMAN [Term] id: CCO:B0071978 name: ZBT7A_HUMAN-Phosphoserine526 def: "Protein ZBT7A_HUMAN with the residue 526 substituted with Phosphoserine" [UniProtKB:O95365] xref: UniProtKB:O95365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054751 ! ZBT7A_HUMAN [Term] id: CCO:B0071979 name: ZBT7A_HUMAN-Phosphoserine549 def: "Protein ZBT7A_HUMAN with the residue 549 substituted with Phosphoserine" [UniProtKB:O95365] xref: UniProtKB:O95365 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054751 ! ZBT7A_HUMAN [Term] id: CCO:B0071980 name: ZBT7C_HUMAN-Phosphotyrosine331 def: "Protein ZBT7C_HUMAN with the residue 331 substituted with Phosphotyrosine" [UniProtKB:A1YPR0] xref: UniProtKB:A1YPR0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: transformation_of CCO:B0043816 ! ZBT7C_HUMAN [Term] id: CCO:B0071981 name: ZBTB1_HUMAN-Phosphothreonine169 def: "Protein ZBTB1_HUMAN with the residue 169 substituted with Phosphothreonine" [UniProtKB:Q9Y2K1] xref: UniProtKB:Q9Y2K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059309 ! ZBTB1_HUMAN [Term] id: CCO:B0071982 name: ZBTB1_HUMAN-Phosphoserine355 def: "Protein ZBTB1_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:Q9Y2K1] xref: UniProtKB:Q9Y2K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059309 ! ZBTB1_HUMAN [Term] id: CCO:B0071983 name: ZBTB1_HUMAN-Phosphothreonine356 def: "Protein ZBTB1_HUMAN with the residue 356 substituted with Phosphothreonine" [UniProtKB:Q9Y2K1] xref: UniProtKB:Q9Y2K1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059309 ! ZBTB1_HUMAN [Term] id: CCO:B0071984 name: ZBTB2_HUMAN-Phosphoserine435 def: "Protein ZBTB2_HUMAN with the residue 435 substituted with Phosphoserine" [UniProtKB:Q8N680] xref: UniProtKB:Q8N680 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057484 ! ZBTB2_HUMAN [Term] id: CCO:B0071985 name: ZBTB9_HUMAN-Phosphothreonine376 def: "Protein ZBTB9_HUMAN with the residue 376 substituted with Phosphothreonine" [UniProtKB:Q96C00] xref: UniProtKB:Q96C00 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058173 ! ZBTB9_HUMAN [Term] id: CCO:B0071986 name: ZDH17_HUMAN-Phosphotyrosine70 def: "Protein ZDH17_HUMAN with the residue 70 substituted with Phosphotyrosine" [UniProtKB:Q8IUH5] xref: UniProtKB:Q8IUH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057324 ! ZDH17_HUMAN [Term] id: CCO:B0071987 name: ZEB1_HUMAN-Phosphoserine31 def: "Protein ZEB1_HUMAN with the residue 31 substituted with Phosphoserine" [UniProtKB:P37275] xref: UniProtKB:P37275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055317 ! ZEB1_HUMAN [Term] id: CCO:B0071988 name: ZEB1_HUMAN-Phosphoserine33 def: "Protein ZEB1_HUMAN with the residue 33 substituted with Phosphoserine" [UniProtKB:P37275] xref: UniProtKB:P37275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055317 ! ZEB1_HUMAN [Term] id: CCO:B0071989 name: ZEB1_HUMAN-Phosphoserine322 def: "Protein ZEB1_HUMAN with the residue 322 substituted with Phosphoserine" [UniProtKB:P37275] xref: UniProtKB:P37275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055317 ! ZEB1_HUMAN [Term] id: CCO:B0071990 name: ZEB1_HUMAN-Phosphoserine646 def: "Protein ZEB1_HUMAN with the residue 646 substituted with Phosphoserine" [UniProtKB:P37275] xref: UniProtKB:P37275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055317 ! ZEB1_HUMAN [Term] id: CCO:B0071991 name: ZEB1_HUMAN-Phosphoserine679 def: "Protein ZEB1_HUMAN with the residue 679 substituted with Phosphoserine" [UniProtKB:P37275] xref: UniProtKB:P37275 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000300 ! transcription coactivator activity relationship: has_function CCO:F0000301 ! transcription corepressor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055317 ! ZEB1_HUMAN [Term] id: CCO:B0071992 name: ZEP1_HUMAN-Phosphoserine1051 def: "Protein ZEP1_HUMAN with the residue 1051 substituted with Phosphoserine" [UniProtKB:P15822] xref: UniProtKB:P15822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:B0071993 name: ZEP1_HUMAN-Phosphoserine1873 def: "Protein ZEP1_HUMAN with the residue 1873 substituted with Phosphoserine" [UniProtKB:P15822] xref: UniProtKB:P15822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:B0071994 name: ZEP1_HUMAN-Phosphoserine1874 def: "Protein ZEP1_HUMAN with the residue 1874 substituted with Phosphoserine" [UniProtKB:P15822] xref: UniProtKB:P15822 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:B0071995 name: ZEP2_HUMAN-Phosphoserine2071 def: "Protein ZEP2_HUMAN with the residue 2071 substituted with Phosphoserine" [UniProtKB:P31629] xref: UniProtKB:P31629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055245 ! ZEP2_HUMAN [Term] id: CCO:B0071996 name: ZEP2_HUMAN-Phosphoserine2077 def: "Protein ZEP2_HUMAN with the residue 2077 substituted with Phosphoserine" [UniProtKB:P31629] xref: UniProtKB:P31629 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055245 ! ZEP2_HUMAN [Term] id: CCO:B0071997 name: ZEP3_HUMAN-Phosphothreonine2037 def: "Protein ZEP3_HUMAN with the residue 2037 substituted with Phosphothreonine" [UniProtKB:Q5T1R4] xref: UniProtKB:Q5T1R4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056564 ! ZEP3_HUMAN [Term] id: CCO:B0071998 name: ZF106_HUMAN-Phosphoserine859 def: "Protein ZF106_HUMAN with the residue 859 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0071999 name: ZF106_HUMAN-Phosphoserine861 def: "Protein ZF106_HUMAN with the residue 861 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072000 name: ZF106_HUMAN-Phosphoserine864 def: "Protein ZF106_HUMAN with the residue 864 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072001 name: ZF106_HUMAN-Phosphoserine937 def: "Protein ZF106_HUMAN with the residue 937 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072002 name: ZF106_HUMAN-Phosphothreonine1021 def: "Protein ZF106_HUMAN with the residue 1021 substituted with Phosphothreonine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072003 name: ZF106_HUMAN-Phosphoserine1025 def: "Protein ZF106_HUMAN with the residue 1025 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072004 name: ZF106_HUMAN-Phosphoserine1026 def: "Protein ZF106_HUMAN with the residue 1026 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000130 ! opioid peptide activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003582 ! SH3 domain binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000244 ! membrane fraction relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000397 ! cytosol relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072005 name: ZF106_HUMAN-Phosphoserine1031 def: "Protein ZF106_HUMAN with the residue 1031 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072006 name: ZF106_HUMAN-Phosphoserine1261 def: "Protein ZF106_HUMAN with the residue 1261 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072007 name: ZF106_HUMAN-Phosphoserine1279 def: "Protein ZF106_HUMAN with the residue 1279 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072008 name: ZF106_HUMAN-Phosphoserine1281 def: "Protein ZF106_HUMAN with the residue 1281 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] comment: By similarity xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072009 name: ZF106_HUMAN-Phosphoserine1328 def: "Protein ZF106_HUMAN with the residue 1328 substituted with Phosphoserine" [UniProtKB:Q9H2Y7] xref: UniProtKB:Q9H2Y7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058692 ! ZF106_HUMAN [Term] id: CCO:B0072010 name: ZFHX3_HUMAN-Phosphoserine267 def: "Protein ZFHX3_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q15911] xref: UniProtKB:Q15911 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056118 ! ZFHX3_HUMAN [Term] id: CCO:B0072011 name: ZFHX3_HUMAN-Phosphoserine571 def: "Protein ZFHX3_HUMAN with the residue 571 substituted with Phosphoserine" [UniProtKB:Q15911] xref: UniProtKB:Q15911 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056118 ! ZFHX3_HUMAN [Term] id: CCO:B0072012 name: ZFHX3_HUMAN-Phosphoserine1180 def: "Protein ZFHX3_HUMAN with the residue 1180 substituted with Phosphoserine" [UniProtKB:Q15911] xref: UniProtKB:Q15911 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0000293 ! RNA polymerase II transcription factor activity, enhancer binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000272 ! transcription factor complex relationship: located_in CCO:C0000325 ! mitochondrion relationship: transformation_of CCO:B0056118 ! ZFHX3_HUMAN [Term] id: CCO:B0072013 name: ZFHX3_HUMAN-Phosphoserine1197 def: "Protein ZFHX3_HUMAN with the residue 1197 substituted with Phosphoserine" [UniProtKB:Q15911] xref: UniProtKB:Q15911 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056118 ! ZFHX3_HUMAN [Term] id: CCO:B0072014 name: ZFHX3_HUMAN-Phosphoserine1204 def: "Protein ZFHX3_HUMAN with the residue 1204 substituted with Phosphoserine" [UniProtKB:Q15911] xref: UniProtKB:Q15911 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056118 ! ZFHX3_HUMAN [Term] id: CCO:B0072015 name: ZFHX3_HUMAN-Phosphoserine1590 def: "Protein ZFHX3_HUMAN with the residue 1590 substituted with Phosphoserine" [UniProtKB:Q15911] comment: By similarity xref: UniProtKB:Q15911 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056118 ! ZFHX3_HUMAN [Term] id: CCO:B0072016 name: ZFHX4_HUMAN-Phosphoserine1892 def: "Protein ZFHX4_HUMAN with the residue 1892 substituted with Phosphoserine" [UniProtKB:Q86UP3] xref: UniProtKB:Q86UP3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057249 ! ZFHX4_HUMAN [Term] id: CCO:B0072017 name: ZFP62_HUMAN-Phosphothreonine266 def: "Protein ZFP62_HUMAN with the residue 266 substituted with Phosphothreonine" [UniProtKB:Q8NB50] xref: UniProtKB:Q8NB50 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0017875 ! ZFP62_HUMAN [Term] id: CCO:B0072018 name: ZFP91_HUMAN-Phosphoserine82 def: "Protein ZFP91_HUMAN with the residue 82 substituted with Phosphoserine" [UniProtKB:Q96JP5] xref: UniProtKB:Q96JP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058247 ! ZFP91_HUMAN [Term] id: CCO:B0072019 name: ZFP91_HUMAN-Phosphoserine83 def: "Protein ZFP91_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q96JP5] xref: UniProtKB:Q96JP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058247 ! ZFP91_HUMAN [Term] id: CCO:B0072020 name: ZFP91_HUMAN-Phosphoserine103 def: "Protein ZFP91_HUMAN with the residue 103 substituted with Phosphoserine" [UniProtKB:Q96JP5] xref: UniProtKB:Q96JP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058247 ! ZFP91_HUMAN [Term] id: CCO:B0072021 name: ZFP91_HUMAN-Phosphothreonine395 def: "Protein ZFP91_HUMAN with the residue 395 substituted with Phosphothreonine" [UniProtKB:Q96JP5] xref: UniProtKB:Q96JP5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058247 ! ZFP91_HUMAN [Term] id: CCO:B0072022 name: ZFX_HUMAN-Phosphoserine274 def: "Protein ZFX_HUMAN with the residue 274 substituted with Phosphoserine" [UniProtKB:P17010] xref: UniProtKB:P17010 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055062 ! ZFX_HUMAN [Term] id: CCO:B0072023 name: ZFY16_HUMAN-Phosphotyrosine219 def: "Protein ZFY16_HUMAN with the residue 219 substituted with Phosphotyrosine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072024 name: ZFY16_HUMAN-Phosphotyrosine221 def: "Protein ZFY16_HUMAN with the residue 221 substituted with Phosphotyrosine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072025 name: ZFY16_HUMAN-Phosphoserine446 def: "Protein ZFY16_HUMAN with the residue 446 substituted with Phosphoserine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072026 name: ZFY16_HUMAN-Phosphoserine815 def: "Protein ZFY16_HUMAN with the residue 815 substituted with Phosphoserine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001668 ! phosphatidylinositol binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0001997 ! protein transporter activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000351 ! endosome relationship: located_in CCO:C0000352 ! early endosome relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0001339 ! early endosome membrane relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072027 name: ZFY16_HUMAN-Phosphoserine845 def: "Protein ZFY16_HUMAN with the residue 845 substituted with Phosphoserine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072028 name: ZFY16_HUMAN-Phosphoserine939 def: "Protein ZFY16_HUMAN with the residue 939 substituted with Phosphoserine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072029 name: ZFY16_HUMAN-Phosphoserine946 def: "Protein ZFY16_HUMAN with the residue 946 substituted with Phosphoserine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072030 name: ZFY16_HUMAN-Phosphothreonine1209 def: "Protein ZFY16_HUMAN with the residue 1209 substituted with Phosphothreonine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072031 name: ZFY16_HUMAN-Phosphoserine1210 def: "Protein ZFY16_HUMAN with the residue 1210 substituted with Phosphoserine" [UniProtKB:Q7Z3T8] xref: UniProtKB:Q7Z3T8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057155 ! ZFY16_HUMAN [Term] id: CCO:B0072032 name: ZHX1_HUMAN-Phosphotyrosine289 def: "Protein ZHX1_HUMAN with the residue 289 substituted with Phosphotyrosine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0072033 name: ZHX1_HUMAN-Phosphotyrosine303 def: "Protein ZHX1_HUMAN with the residue 303 substituted with Phosphotyrosine" [UniProtKB:Q9UKY1] xref: UniProtKB:Q9UKY1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:B0072034 name: ZHX2_HUMAN-Phosphoserine16 def: "Protein ZHX2_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q9Y6X8] comment: By similarity xref: UniProtKB:Q9Y6X8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022038 ! ZHX2_HUMAN [Term] id: CCO:B0072035 name: ZHX3_HUMAN-Phosphoserine680 def: "Protein ZHX3_HUMAN with the residue 680 substituted with Phosphoserine" [UniProtKB:Q9H4I2] xref: UniProtKB:Q9H4I2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005877 ! sequence-specific DNA binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0022040 ! ZHX3_HUMAN [Term] id: CCO:B0072036 name: ZHX3_HUMAN-Phosphoserine723 def: "Protein ZHX3_HUMAN with the residue 723 substituted with Phosphoserine" [UniProtKB:Q9H4I2] xref: UniProtKB:Q9H4I2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022040 ! ZHX3_HUMAN [Term] id: CCO:B0072037 name: ZHX3_HUMAN-Phosphoserine946 def: "Protein ZHX3_HUMAN with the residue 946 substituted with Phosphoserine" [UniProtKB:Q9H4I2] xref: UniProtKB:Q9H4I2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0022040 ! ZHX3_HUMAN [Term] id: CCO:B0072038 name: ZKSC1_HUMAN-Phosphoserine13 def: "Protein ZKSC1_HUMAN with the residue 13 substituted with Phosphoserine" [UniProtKB:P17029] xref: UniProtKB:P17029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055073 ! ZKSC1_HUMAN [Term] id: CCO:B0072039 name: ZKSC1_HUMAN-Phosphoserine471 def: "Protein ZKSC1_HUMAN with the residue 471 substituted with Phosphoserine" [UniProtKB:P17029] xref: UniProtKB:P17029 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055073 ! ZKSC1_HUMAN [Term] id: CCO:B0072040 name: ZKSC2_HUMAN-Phosphoserine591 def: "Protein ZKSC2_HUMAN with the residue 591 substituted with Phosphoserine" [UniProtKB:Q63HK3] xref: UniProtKB:Q63HK3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056686 ! ZKSC2_HUMAN [Term] id: CCO:B0072041 name: ZKSC2_HUMAN-Phosphothreonine594 def: "Protein ZKSC2_HUMAN with the residue 594 substituted with Phosphothreonine" [UniProtKB:Q63HK3] xref: UniProtKB:Q63HK3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056686 ! ZKSC2_HUMAN [Term] id: CCO:B0072042 name: ZKSC2_HUMAN-Phosphoserine600 def: "Protein ZKSC2_HUMAN with the residue 600 substituted with Phosphoserine" [UniProtKB:Q63HK3] xref: UniProtKB:Q63HK3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056686 ! ZKSC2_HUMAN [Term] id: CCO:B0072043 name: ZKSC4_HUMAN-Phosphoserine165 def: "Protein ZKSC4_HUMAN with the residue 165 substituted with Phosphoserine" [UniProtKB:Q969J2] xref: UniProtKB:Q969J2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058133 ! ZKSC4_HUMAN [Term] id: CCO:B0072044 name: ZMYM2_HUMAN-Phosphoserine305 def: "Protein ZMYM2_HUMAN with the residue 305 substituted with Phosphoserine" [UniProtKB:Q9UBW7] xref: UniProtKB:Q9UBW7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000200 ! cellular_component relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059088 ! ZMYM2_HUMAN [Term] id: CCO:B0072045 name: ZMYM2_HUMAN-Phosphoserine362 def: "Protein ZMYM2_HUMAN with the residue 362 substituted with Phosphoserine" [UniProtKB:Q9UBW7] xref: UniProtKB:Q9UBW7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059088 ! ZMYM2_HUMAN [Term] id: CCO:B0072046 name: ZMYM2_HUMAN-Phosphoserine838 def: "Protein ZMYM2_HUMAN with the residue 838 substituted with Phosphoserine" [UniProtKB:Q9UBW7] xref: UniProtKB:Q9UBW7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059088 ! ZMYM2_HUMAN [Term] id: CCO:B0072047 name: ZMYM2_HUMAN-Phosphothreonine1376 def: "Protein ZMYM2_HUMAN with the residue 1376 substituted with Phosphothreonine" [UniProtKB:Q9UBW7] xref: UniProtKB:Q9UBW7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059088 ! ZMYM2_HUMAN [Term] id: CCO:B0072048 name: ZN101_HUMAN-Phosphoserine433 def: "Protein ZN101_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:Q8IZC7] xref: UniProtKB:Q8IZC7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057401 ! ZN101_HUMAN [Term] id: CCO:B0072049 name: ZN142_HUMAN-Phosphoserine1319 def: "Protein ZN142_HUMAN with the residue 1319 substituted with Phosphoserine" [UniProtKB:P52746] xref: UniProtKB:P52746 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0002378 ! electron carrier activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055498 ! ZN142_HUMAN [Term] id: CCO:B0072050 name: ZN148_HUMAN-Phosphothreonine194 def: "Protein ZN148_HUMAN with the residue 194 substituted with Phosphothreonine" [UniProtKB:Q9UQR1] xref: UniProtKB:Q9UQR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059285 ! ZN148_HUMAN [Term] id: CCO:B0072051 name: ZN148_HUMAN-Phosphoserine250 def: "Protein ZN148_HUMAN with the residue 250 substituted with Phosphoserine" [UniProtKB:Q9UQR1] xref: UniProtKB:Q9UQR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059285 ! ZN148_HUMAN [Term] id: CCO:B0072052 name: ZN148_HUMAN-Phosphothreonine305 def: "Protein ZN148_HUMAN with the residue 305 substituted with Phosphothreonine" [UniProtKB:Q9UQR1] comment: By similarity xref: UniProtKB:Q9UQR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059285 ! ZN148_HUMAN [Term] id: CCO:B0072053 name: ZN148_HUMAN-Phosphoserine306 def: "Protein ZN148_HUMAN with the residue 306 substituted with Phosphoserine" [UniProtKB:Q9UQR1] xref: UniProtKB:Q9UQR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: transformation_of CCO:B0059285 ! ZN148_HUMAN [Term] id: CCO:B0072054 name: ZN148_HUMAN-Phosphoserine412 def: "Protein ZN148_HUMAN with the residue 412 substituted with Phosphoserine" [UniProtKB:Q9UQR1] xref: UniProtKB:Q9UQR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059285 ! ZN148_HUMAN [Term] id: CCO:B0072055 name: ZN148_HUMAN-Phosphoserine784 def: "Protein ZN148_HUMAN with the residue 784 substituted with Phosphoserine" [UniProtKB:Q9UQR1] xref: UniProtKB:Q9UQR1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059285 ! ZN148_HUMAN [Term] id: CCO:B0072056 name: ZN160_HUMAN-Phosphothreonine588 def: "Protein ZN160_HUMAN with the residue 588 substituted with Phosphothreonine" [UniProtKB:Q9HCG1] xref: UniProtKB:Q9HCG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058806 ! ZN160_HUMAN [Term] id: CCO:B0072057 name: ZN169_HUMAN-Phosphoserine145 def: "Protein ZN169_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:Q14929] xref: UniProtKB:Q14929 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056025 ! ZN169_HUMAN [Term] id: CCO:B0072058 name: ZN174_HUMAN-Phosphotyrosine382 def: "Protein ZN174_HUMAN with the residue 382 substituted with Phosphotyrosine" [UniProtKB:Q15697] xref: UniProtKB:Q15697 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056096 ! ZN174_HUMAN [Term] id: CCO:B0072059 name: ZN180_HUMAN-Phosphoserine68 def: "Protein ZN180_HUMAN with the residue 68 substituted with Phosphoserine" [UniProtKB:Q9UJW8] xref: UniProtKB:Q9UJW8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059179 ! ZN180_HUMAN [Term] id: CCO:B0072060 name: ZN192_HUMAN-Phosphoserine12 def: "Protein ZN192_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q15776] xref: UniProtKB:Q15776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056110 ! ZN192_HUMAN [Term] id: CCO:B0072061 name: ZN192_HUMAN-Phosphoserine183 def: "Protein ZN192_HUMAN with the residue 183 substituted with Phosphoserine" [UniProtKB:Q15776] xref: UniProtKB:Q15776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056110 ! ZN192_HUMAN [Term] id: CCO:B0072062 name: ZN192_HUMAN-Phosphoserine191 def: "Protein ZN192_HUMAN with the residue 191 substituted with Phosphoserine" [UniProtKB:Q15776] xref: UniProtKB:Q15776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056110 ! ZN192_HUMAN [Term] id: CCO:B0072063 name: ZN192_HUMAN-Phosphothreonine195 def: "Protein ZN192_HUMAN with the residue 195 substituted with Phosphothreonine" [UniProtKB:Q15776] xref: UniProtKB:Q15776 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056110 ! ZN192_HUMAN [Term] id: CCO:B0072064 name: ZN217_HUMAN-Phosphoserine407 def: "Protein ZN217_HUMAN with the residue 407 substituted with Phosphoserine" [UniProtKB:O75362] xref: UniProtKB:O75362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054623 ! ZN217_HUMAN [Term] id: CCO:B0072065 name: ZN217_HUMAN-Phosphoserine570 def: "Protein ZN217_HUMAN with the residue 570 substituted with Phosphoserine" [UniProtKB:O75362] xref: UniProtKB:O75362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054623 ! ZN217_HUMAN [Term] id: CCO:B0072066 name: ZN217_HUMAN-Phosphoserine795 def: "Protein ZN217_HUMAN with the residue 795 substituted with Phosphoserine" [UniProtKB:O75362] xref: UniProtKB:O75362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054623 ! ZN217_HUMAN [Term] id: CCO:B0072067 name: ZN217_HUMAN-Phosphoserine848 def: "Protein ZN217_HUMAN with the residue 848 substituted with Phosphoserine" [UniProtKB:O75362] xref: UniProtKB:O75362 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054623 ! ZN217_HUMAN [Term] id: CCO:B0072068 name: ZN219_HUMAN-Phosphoserine175 def: "Protein ZN219_HUMAN with the residue 175 substituted with Phosphoserine" [UniProtKB:Q9P2Y4] xref: UniProtKB:Q9P2Y4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059063 ! ZN219_HUMAN [Term] id: CCO:B0072069 name: ZN224_HUMAN-Phosphoserine245 def: "Protein ZN224_HUMAN with the residue 245 substituted with Phosphoserine" [UniProtKB:Q9NZL3] xref: UniProtKB:Q9NZL3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059004 ! ZN224_HUMAN [Term] id: CCO:B0072070 name: ZN225_HUMAN-Phosphothreonine283 def: "Protein ZN225_HUMAN with the residue 283 substituted with Phosphothreonine" [UniProtKB:Q9UK10] xref: UniProtKB:Q9UK10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059183 ! ZN225_HUMAN [Term] id: CCO:B0072071 name: ZN238_HUMAN-Phosphoserine516 def: "Protein ZN238_HUMAN with the residue 516 substituted with Phosphoserine" [UniProtKB:Q99592] xref: UniProtKB:Q99592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000040 ! nuclear chromosome relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058428 ! ZN238_HUMAN [Term] id: CCO:B0072072 name: ZN238_HUMAN-Phosphoserine517 def: "Protein ZN238_HUMAN with the residue 517 substituted with Phosphoserine" [UniProtKB:Q99592] xref: UniProtKB:Q99592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058428 ! ZN238_HUMAN [Term] id: CCO:B0072073 name: ZN239_HUMAN-Phosphoserine41 def: "Protein ZN239_HUMAN with the residue 41 substituted with Phosphoserine" [UniProtKB:Q16600] xref: UniProtKB:Q16600 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056157 ! ZN239_HUMAN [Term] id: CCO:B0072074 name: ZN248_HUMAN-Phosphoserine142 def: "Protein ZN248_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q8NDW4] xref: UniProtKB:Q8NDW4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057583 ! ZN248_HUMAN [Term] id: CCO:B0072075 name: ZN254_HUMAN-Phosphothreonine625 def: "Protein ZN254_HUMAN with the residue 625 substituted with Phosphothreonine" [UniProtKB:O75437] xref: UniProtKB:O75437 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054635 ! ZN254_HUMAN [Term] id: CCO:B0072076 name: ZN264_HUMAN-Phosphoserine80 def: "Protein ZN264_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:O43296] xref: UniProtKB:O43296 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054467 ! ZN264_HUMAN [Term] id: CCO:B0072077 name: ZN264_HUMAN-Phosphotyrosine343 def: "Protein ZN264_HUMAN with the residue 343 substituted with Phosphotyrosine" [UniProtKB:O43296] xref: UniProtKB:O43296 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054467 ! ZN264_HUMAN [Term] id: CCO:B0072078 name: ZN264_HUMAN-Phosphotyrosine483 def: "Protein ZN264_HUMAN with the residue 483 substituted with Phosphotyrosine" [UniProtKB:O43296] xref: UniProtKB:O43296 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054467 ! ZN264_HUMAN [Term] id: CCO:B0072079 name: ZN264_HUMAN-Phosphotyrosine511 def: "Protein ZN264_HUMAN with the residue 511 substituted with Phosphotyrosine" [UniProtKB:O43296] xref: UniProtKB:O43296 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054467 ! ZN264_HUMAN [Term] id: CCO:B0072080 name: ZN267_HUMAN-Phosphothreonine424 def: "Protein ZN267_HUMAN with the residue 424 substituted with Phosphothreonine" [UniProtKB:Q14586] xref: UniProtKB:Q14586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055998 ! ZN267_HUMAN [Term] id: CCO:B0072081 name: ZN267_HUMAN-Phosphotyrosine520 def: "Protein ZN267_HUMAN with the residue 520 substituted with Phosphotyrosine" [UniProtKB:Q14586] xref: UniProtKB:Q14586 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055998 ! ZN267_HUMAN [Term] id: CCO:B0072082 name: ZN276_HUMAN-Phosphoserine90 def: "Protein ZN276_HUMAN with the residue 90 substituted with Phosphoserine" [UniProtKB:Q8N554] xref: UniProtKB:Q8N554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057470 ! ZN276_HUMAN [Term] id: CCO:B0072083 name: ZN276_HUMAN-Phosphoserine93 def: "Protein ZN276_HUMAN with the residue 93 substituted with Phosphoserine" [UniProtKB:Q8N554] xref: UniProtKB:Q8N554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057470 ! ZN276_HUMAN [Term] id: CCO:B0072084 name: ZN276_HUMAN-Phosphoserine357 def: "Protein ZN276_HUMAN with the residue 357 substituted with Phosphoserine" [UniProtKB:Q8N554] comment: By similarity xref: UniProtKB:Q8N554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057470 ! ZN276_HUMAN [Term] id: CCO:B0072085 name: ZN276_HUMAN-Phosphoserine360 def: "Protein ZN276_HUMAN with the residue 360 substituted with Phosphoserine" [UniProtKB:Q8N554] comment: By similarity xref: UniProtKB:Q8N554 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057470 ! ZN276_HUMAN [Term] id: CCO:B0072086 name: ZN281_HUMAN-Phosphoserine395 def: "Protein ZN281_HUMAN with the residue 395 substituted with Phosphoserine" [UniProtKB:Q9Y2X9] xref: UniProtKB:Q9Y2X9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059321 ! ZN281_HUMAN [Term] id: CCO:B0072087 name: ZN281_HUMAN-Phosphoserine484 def: "Protein ZN281_HUMAN with the residue 484 substituted with Phosphoserine" [UniProtKB:Q9Y2X9] xref: UniProtKB:Q9Y2X9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000292 ! specific RNA polymerase II transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: transformation_of CCO:B0059321 ! ZN281_HUMAN [Term] id: CCO:B0072088 name: ZN281_HUMAN-Phosphoserine785 def: "Protein ZN281_HUMAN with the residue 785 substituted with Phosphoserine" [UniProtKB:Q9Y2X9] xref: UniProtKB:Q9Y2X9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059321 ! ZN281_HUMAN [Term] id: CCO:B0072089 name: ZN281_HUMAN-Phosphoserine807 def: "Protein ZN281_HUMAN with the residue 807 substituted with Phosphoserine" [UniProtKB:Q9Y2X9] xref: UniProtKB:Q9Y2X9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059321 ! ZN281_HUMAN [Term] id: CCO:B0072090 name: ZN282_HUMAN-Phosphotyrosine161 def: "Protein ZN282_HUMAN with the residue 161 substituted with Phosphotyrosine" [UniProtKB:Q9UDV7] xref: UniProtKB:Q9UDV7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059105 ! ZN282_HUMAN [Term] id: CCO:B0072091 name: ZN292_HUMAN-Phosphoserine66 def: "Protein ZN292_HUMAN with the residue 66 substituted with Phosphoserine" [UniProtKB:O60281] xref: UniProtKB:O60281 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054539 ! ZN292_HUMAN [Term] id: CCO:B0072092 name: ZN295_HUMAN-Phosphothreonine431 def: "Protein ZN295_HUMAN with the residue 431 substituted with Phosphothreonine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0072093 name: ZN295_HUMAN-Phosphoserine434 def: "Protein ZN295_HUMAN with the residue 434 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0072094 name: ZN295_HUMAN-Phosphoserine438 def: "Protein ZN295_HUMAN with the residue 438 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0072095 name: ZN295_HUMAN-Phosphoserine605 def: "Protein ZN295_HUMAN with the residue 605 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0072096 name: ZN295_HUMAN-Phosphoserine759 def: "Protein ZN295_HUMAN with the residue 759 substituted with Phosphoserine" [UniProtKB:Q9ULJ3] xref: UniProtKB:Q9ULJ3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0037120 ! ZN295_HUMAN [Term] id: CCO:B0072097 name: ZN318_HUMAN-Phosphoserine79 def: "Protein ZN318_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072098 name: ZN318_HUMAN-Phosphoserine81 def: "Protein ZN318_HUMAN with the residue 81 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072099 name: ZN318_HUMAN-Phosphoserine136 def: "Protein ZN318_HUMAN with the residue 136 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072100 name: ZN318_HUMAN-Phosphoserine173 def: "Protein ZN318_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072101 name: ZN318_HUMAN-Phosphoserine214 def: "Protein ZN318_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072102 name: ZN318_HUMAN-Phosphoserine1420 def: "Protein ZN318_HUMAN with the residue 1420 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072103 name: ZN318_HUMAN-Phosphoserine1896 def: "Protein ZN318_HUMAN with the residue 1896 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072104 name: ZN318_HUMAN-Phosphoserine2189 def: "Protein ZN318_HUMAN with the residue 2189 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072105 name: ZN318_HUMAN-Phosphoserine2192 def: "Protein ZN318_HUMAN with the residue 2192 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072106 name: ZN318_HUMAN-Phosphoserine2243 def: "Protein ZN318_HUMAN with the residue 2243 substituted with Phosphoserine" [UniProtKB:Q5VUA4] xref: UniProtKB:Q5VUA4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0032820 ! ZN318_HUMAN [Term] id: CCO:B0072107 name: ZN326_HUMAN-Phosphoserine137 def: "Protein ZN326_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q5BKZ1] xref: UniProtKB:Q5BKZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018465 ! ZN326_HUMAN [Term] id: CCO:B0072108 name: ZN326_HUMAN-Phosphoserine270 def: "Protein ZN326_HUMAN with the residue 270 substituted with Phosphoserine" [UniProtKB:Q5BKZ1] xref: UniProtKB:Q5BKZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018465 ! ZN326_HUMAN [Term] id: CCO:B0072109 name: ZN326_HUMAN-Phosphothreonine274 def: "Protein ZN326_HUMAN with the residue 274 substituted with Phosphothreonine" [UniProtKB:Q5BKZ1] xref: UniProtKB:Q5BKZ1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0018465 ! ZN326_HUMAN [Term] id: CCO:B0072110 name: ZN330_HUMAN-Phosphotyrosine308 def: "Protein ZN330_HUMAN with the residue 308 substituted with Phosphotyrosine" [UniProtKB:Q9Y3S2] xref: UniProtKB:Q9Y3S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063163 ! ZN330_HUMAN [Term] id: CCO:B0072111 name: ZN330_HUMAN-Phosphotyrosine315 def: "Protein ZN330_HUMAN with the residue 315 substituted with Phosphotyrosine" [UniProtKB:Q9Y3S2] xref: UniProtKB:Q9Y3S2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063163 ! ZN330_HUMAN [Term] id: CCO:B0072112 name: ZN335_HUMAN-Phosphoserine416 def: "Protein ZN335_HUMAN with the residue 416 substituted with Phosphoserine" [UniProtKB:Q9H4Z2] xref: UniProtKB:Q9H4Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058721 ! ZN335_HUMAN [Term] id: CCO:B0072113 name: ZN335_HUMAN-Phosphoserine976 def: "Protein ZN335_HUMAN with the residue 976 substituted with Phosphoserine" [UniProtKB:Q9H4Z2] xref: UniProtKB:Q9H4Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058721 ! ZN335_HUMAN [Term] id: CCO:B0072114 name: ZN335_HUMAN-Phosphoserine1153 def: "Protein ZN335_HUMAN with the residue 1153 substituted with Phosphoserine" [UniProtKB:Q9H4Z2] xref: UniProtKB:Q9H4Z2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058721 ! ZN335_HUMAN [Term] id: CCO:B0072115 name: ZN33A_HUMAN-Phosphoserine267 def: "Protein ZN33A_HUMAN with the residue 267 substituted with Phosphoserine" [UniProtKB:Q06730] xref: UniProtKB:Q06730 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055772 ! ZN33A_HUMAN [Term] id: CCO:B0072116 name: ZN367_HUMAN-Phosphoserine310 def: "Protein ZN367_HUMAN with the residue 310 substituted with Phosphoserine" [UniProtKB:Q7RTV3] xref: UniProtKB:Q7RTV3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057138 ! ZN367_HUMAN [Term] id: CCO:B0072117 name: ZN384_HUMAN-Phosphoserine214 def: "Protein ZN384_HUMAN with the residue 214 substituted with Phosphoserine" [UniProtKB:Q8TF68] xref: UniProtKB:Q8TF68 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057966 ! ZN384_HUMAN [Term] id: CCO:B0072118 name: ZN391_HUMAN-Phosphoserine36 def: "Protein ZN391_HUMAN with the residue 36 substituted with Phosphoserine" [UniProtKB:Q9UJN7] xref: UniProtKB:Q9UJN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059173 ! ZN391_HUMAN [Term] id: CCO:B0072119 name: ZN391_HUMAN-Phosphothreonine49 def: "Protein ZN391_HUMAN with the residue 49 substituted with Phosphothreonine" [UniProtKB:Q9UJN7] xref: UniProtKB:Q9UJN7 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059173 ! ZN391_HUMAN [Term] id: CCO:B0072120 name: ZN397_HUMAN-Phosphoserine159 def: "Protein ZN397_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:Q8NF99] xref: UniProtKB:Q8NF99 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057597 ! ZN397_HUMAN [Term] id: CCO:B0072121 name: ZN420_HUMAN-Phosphoserine488 def: "Protein ZN420_HUMAN with the residue 488 substituted with Phosphoserine" [UniProtKB:Q8TAQ5] xref: UniProtKB:Q8TAQ5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057891 ! ZN420_HUMAN [Term] id: CCO:B0072122 name: ZN423_HUMAN-Phosphoserine599 def: "Protein ZN423_HUMAN with the residue 599 substituted with Phosphoserine" [UniProtKB:Q2M1K9] xref: UniProtKB:Q2M1K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056205 ! ZN423_HUMAN [Term] id: CCO:B0072123 name: ZN423_HUMAN-Phosphoserine604 def: "Protein ZN423_HUMAN with the residue 604 substituted with Phosphoserine" [UniProtKB:Q2M1K9] xref: UniProtKB:Q2M1K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056205 ! ZN423_HUMAN [Term] id: CCO:B0072124 name: ZN423_HUMAN-Phosphoserine608 def: "Protein ZN423_HUMAN with the residue 608 substituted with Phosphoserine" [UniProtKB:Q2M1K9] xref: UniProtKB:Q2M1K9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0003205 ! transcription activator activity relationship: has_function CCO:F0003206 ! transcription repressor activity relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056205 ! ZN423_HUMAN [Term] id: CCO:B0072125 name: ZN432_HUMAN-Nitrated tyrosine41 def: "Protein ZN432_HUMAN with the residue 41 substituted with Nitrated tyrosine" [UniProtKB:O94892] xref: UniProtKB:O94892 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0054706 ! ZN432_HUMAN [Term] id: CCO:B0072126 name: ZN444_HUMAN-Phosphoserine232 def: "Protein ZN444_HUMAN with the residue 232 substituted with Phosphoserine" [UniProtKB:Q8N0Y2] xref: UniProtKB:Q8N0Y2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057416 ! ZN444_HUMAN [Term] id: CCO:B0072127 name: ZN444_HUMAN-Phosphoserine235 def: "Protein ZN444_HUMAN with the residue 235 substituted with Phosphoserine" [UniProtKB:Q8N0Y2] xref: UniProtKB:Q8N0Y2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057416 ! ZN444_HUMAN [Term] id: CCO:B0072128 name: ZN460_HUMAN-Phosphoserine367 def: "Protein ZN460_HUMAN with the residue 367 substituted with Phosphoserine" [UniProtKB:Q14592] xref: UniProtKB:Q14592 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056003 ! ZN460_HUMAN [Term] id: CCO:B0072129 name: ZN462_HUMAN-Phosphotyrosine989 def: "Protein ZN462_HUMAN with the residue 989 substituted with Phosphotyrosine" [UniProtKB:Q96JM2] xref: UniProtKB:Q96JM2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058244 ! ZN462_HUMAN [Term] id: CCO:B0072130 name: ZN462_HUMAN-Phosphoserine1330 def: "Protein ZN462_HUMAN with the residue 1330 substituted with Phosphoserine" [UniProtKB:Q96JM2] xref: UniProtKB:Q96JM2 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058244 ! ZN462_HUMAN [Term] id: CCO:B0072131 name: ZN469_HUMAN-Phosphothreonine1553 def: "Protein ZN469_HUMAN with the residue 1553 substituted with Phosphothreonine" [UniProtKB:Q96JG9] xref: UniProtKB:Q96JG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058239 ! ZN469_HUMAN [Term] id: CCO:B0072132 name: ZN469_HUMAN-Phosphoserine3623 def: "Protein ZN469_HUMAN with the residue 3623 substituted with Phosphoserine" [UniProtKB:Q96JG9] xref: UniProtKB:Q96JG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058239 ! ZN469_HUMAN [Term] id: CCO:B0072133 name: ZN469_HUMAN-Phosphoserine3624 def: "Protein ZN469_HUMAN with the residue 3624 substituted with Phosphoserine" [UniProtKB:Q96JG9] xref: UniProtKB:Q96JG9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058239 ! ZN469_HUMAN [Term] id: CCO:B0072134 name: ZN470_HUMAN-Phosphothreonine160 def: "Protein ZN470_HUMAN with the residue 160 substituted with Phosphothreonine" [UniProtKB:Q6ECI4] xref: UniProtKB:Q6ECI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056731 ! ZN470_HUMAN [Term] id: CCO:B0072135 name: ZN470_HUMAN-Phosphothreonine162 def: "Protein ZN470_HUMAN with the residue 162 substituted with Phosphothreonine" [UniProtKB:Q6ECI4] xref: UniProtKB:Q6ECI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056731 ! ZN470_HUMAN [Term] id: CCO:B0072136 name: ZN470_HUMAN-Phosphothreonine166 def: "Protein ZN470_HUMAN with the residue 166 substituted with Phosphothreonine" [UniProtKB:Q6ECI4] xref: UniProtKB:Q6ECI4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056731 ! ZN470_HUMAN [Term] id: CCO:B0072137 name: ZN496_HUMAN-Phosphoserine185 def: "Protein ZN496_HUMAN with the residue 185 substituted with Phosphoserine" [UniProtKB:Q96IT1] xref: UniProtKB:Q96IT1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000289 ! transcription factor activity relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058233 ! ZN496_HUMAN [Term] id: CCO:B0072138 name: ZN507_HUMAN-Phosphoserine195 def: "Protein ZN507_HUMAN with the residue 195 substituted with Phosphoserine" [UniProtKB:Q8TCN5] xref: UniProtKB:Q8TCN5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057915 ! ZN507_HUMAN [Term] id: CCO:B0072139 name: ZN509_HUMAN-Phosphotyrosine652 def: "Protein ZN509_HUMAN with the residue 652 substituted with Phosphotyrosine" [UniProtKB:Q6ZSB9] xref: UniProtKB:Q6ZSB9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057052 ! ZN509_HUMAN [Term] id: CCO:B0072140 name: ZN516_HUMAN-Phosphoserine116 def: "Protein ZN516_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q92618] xref: UniProtKB:Q92618 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058074 ! ZN516_HUMAN [Term] id: CCO:B0072141 name: ZN532_HUMAN-Phosphoserine130 def: "Protein ZN532_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q9HCE3] xref: UniProtKB:Q9HCE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058803 ! ZN532_HUMAN [Term] id: CCO:B0072142 name: ZN532_HUMAN-Phosphoserine133 def: "Protein ZN532_HUMAN with the residue 133 substituted with Phosphoserine" [UniProtKB:Q9HCE3] xref: UniProtKB:Q9HCE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058803 ! ZN532_HUMAN [Term] id: CCO:B0072143 name: ZN532_HUMAN-Phosphoserine134 def: "Protein ZN532_HUMAN with the residue 134 substituted with Phosphoserine" [UniProtKB:Q9HCE3] xref: UniProtKB:Q9HCE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058803 ! ZN532_HUMAN [Term] id: CCO:B0072144 name: ZN532_HUMAN-Phosphothreonine205 def: "Protein ZN532_HUMAN with the residue 205 substituted with Phosphothreonine" [UniProtKB:Q9HCE3] xref: UniProtKB:Q9HCE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058803 ! ZN532_HUMAN [Term] id: CCO:B0072145 name: ZN532_HUMAN-Phosphoserine263 def: "Protein ZN532_HUMAN with the residue 263 substituted with Phosphoserine" [UniProtKB:Q9HCE3] xref: UniProtKB:Q9HCE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058803 ! ZN532_HUMAN [Term] id: CCO:B0072146 name: ZN532_HUMAN-Phosphoserine268 def: "Protein ZN532_HUMAN with the residue 268 substituted with Phosphoserine" [UniProtKB:Q9HCE3] xref: UniProtKB:Q9HCE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058803 ! ZN532_HUMAN [Term] id: CCO:B0072147 name: ZN532_HUMAN-Phosphoserine269 def: "Protein ZN532_HUMAN with the residue 269 substituted with Phosphoserine" [UniProtKB:Q9HCE3] xref: UniProtKB:Q9HCE3 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058803 ! ZN532_HUMAN [Term] id: CCO:B0072148 name: ZN550_HUMAN-Phosphotyrosine259 def: "Protein ZN550_HUMAN with the residue 259 substituted with Phosphotyrosine" [UniProtKB:Q7Z398] xref: UniProtKB:Q7Z398 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057146 ! ZN550_HUMAN [Term] id: CCO:B0072149 name: ZN551_HUMAN-Phosphoserine9 def: "Protein ZN551_HUMAN with the residue 9 substituted with Phosphoserine" [UniProtKB:Q7Z340] xref: UniProtKB:Q7Z340 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057144 ! ZN551_HUMAN [Term] id: CCO:B0072150 name: ZN551_HUMAN-Phosphoserine12 def: "Protein ZN551_HUMAN with the residue 12 substituted with Phosphoserine" [UniProtKB:Q7Z340] xref: UniProtKB:Q7Z340 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057144 ! ZN551_HUMAN [Term] id: CCO:B0072151 name: ZN574_HUMAN-Phosphoserine113 def: "Protein ZN574_HUMAN with the residue 113 substituted with Phosphoserine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072152 name: ZN574_HUMAN-Phosphoserine137 def: "Protein ZN574_HUMAN with the residue 137 substituted with Phosphoserine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072153 name: ZN574_HUMAN-Phosphothreonine154 def: "Protein ZN574_HUMAN with the residue 154 substituted with Phosphothreonine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072154 name: ZN574_HUMAN-Phosphoserine164 def: "Protein ZN574_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072155 name: ZN574_HUMAN-Phosphoserine298 def: "Protein ZN574_HUMAN with the residue 298 substituted with Phosphoserine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072156 name: ZN574_HUMAN-Phosphoserine717 def: "Protein ZN574_HUMAN with the residue 717 substituted with Phosphoserine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072157 name: ZN574_HUMAN-Phosphothreonine724 def: "Protein ZN574_HUMAN with the residue 724 substituted with Phosphothreonine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072158 name: ZN574_HUMAN-Phosphoserine728 def: "Protein ZN574_HUMAN with the residue 728 substituted with Phosphoserine" [UniProtKB:Q6ZN55] xref: UniProtKB:Q6ZN55 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057012 ! ZN574_HUMAN [Term] id: CCO:B0072159 name: ZN576_HUMAN-Phosphothreonine120 def: "Protein ZN576_HUMAN with the residue 120 substituted with Phosphothreonine" [UniProtKB:Q9H609] xref: UniProtKB:Q9H609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058730 ! ZN576_HUMAN [Term] id: CCO:B0072160 name: ZN576_HUMAN-Phosphoserine126 def: "Protein ZN576_HUMAN with the residue 126 substituted with Phosphoserine" [UniProtKB:Q9H609] xref: UniProtKB:Q9H609 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058730 ! ZN576_HUMAN [Term] id: CCO:B0072161 name: ZN579_HUMAN-Phosphoserine483 def: "Protein ZN579_HUMAN with the residue 483 substituted with Phosphoserine" [UniProtKB:Q8NAF0] xref: UniProtKB:Q8NAF0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057546 ! ZN579_HUMAN [Term] id: CCO:B0072162 name: ZN592_HUMAN-Phosphothreonine137 def: "Protein ZN592_HUMAN with the residue 137 substituted with Phosphothreonine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072163 name: ZN592_HUMAN-Phosphoserine142 def: "Protein ZN592_HUMAN with the residue 142 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072164 name: ZN592_HUMAN-Phosphoserine145 def: "Protein ZN592_HUMAN with the residue 145 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072165 name: ZN592_HUMAN-Phosphoserine146 def: "Protein ZN592_HUMAN with the residue 146 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072166 name: ZN592_HUMAN-Phosphoserine331 def: "Protein ZN592_HUMAN with the residue 331 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072167 name: ZN592_HUMAN-Phosphoserine334 def: "Protein ZN592_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072168 name: ZN592_HUMAN-Phosphoserine368 def: "Protein ZN592_HUMAN with the residue 368 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072169 name: ZN592_HUMAN-Phosphoserine460 def: "Protein ZN592_HUMAN with the residue 460 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072170 name: ZN592_HUMAN-Phosphoserine573 def: "Protein ZN592_HUMAN with the residue 573 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072171 name: ZN592_HUMAN-Phosphoserine691 def: "Protein ZN592_HUMAN with the residue 691 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072172 name: ZN592_HUMAN-Phosphoserine1089 def: "Protein ZN592_HUMAN with the residue 1089 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072173 name: ZN592_HUMAN-Phosphoserine1205 def: "Protein ZN592_HUMAN with the residue 1205 substituted with Phosphoserine" [UniProtKB:Q92610] comment: By similarity xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072174 name: ZN592_HUMAN-Phosphoserine1250 def: "Protein ZN592_HUMAN with the residue 1250 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072175 name: ZN592_HUMAN-Phosphoserine1255 def: "Protein ZN592_HUMAN with the residue 1255 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072176 name: ZN592_HUMAN-Phosphoserine1264 def: "Protein ZN592_HUMAN with the residue 1264 substituted with Phosphoserine" [UniProtKB:Q92610] xref: UniProtKB:Q92610 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058071 ! ZN592_HUMAN [Term] id: CCO:B0072177 name: ZN600_HUMAN-Phosphoserine116 def: "Protein ZN600_HUMAN with the residue 116 substituted with Phosphoserine" [UniProtKB:Q6ZNG1] xref: UniProtKB:Q6ZNG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057023 ! ZN600_HUMAN [Term] id: CCO:B0072178 name: ZN600_HUMAN-Phosphoserine124 def: "Protein ZN600_HUMAN with the residue 124 substituted with Phosphoserine" [UniProtKB:Q6ZNG1] xref: UniProtKB:Q6ZNG1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057023 ! ZN600_HUMAN [Term] id: CCO:B0072179 name: ZN609_HUMAN-Phosphoserine576 def: "Protein ZN609_HUMAN with the residue 576 substituted with Phosphoserine" [UniProtKB:O15014] xref: UniProtKB:O15014 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063330 ! ZN609_HUMAN [Term] id: CCO:B0072180 name: ZN609_HUMAN-Phosphoserine578 def: "Protein ZN609_HUMAN with the residue 578 substituted with Phosphoserine" [UniProtKB:O15014] xref: UniProtKB:O15014 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063330 ! ZN609_HUMAN [Term] id: CCO:B0072181 name: ZN609_HUMAN-Phosphoserine842 def: "Protein ZN609_HUMAN with the residue 842 substituted with Phosphoserine" [UniProtKB:O15014] xref: UniProtKB:O15014 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063330 ! ZN609_HUMAN [Term] id: CCO:B0072182 name: ZN609_HUMAN-Phosphoserine846 def: "Protein ZN609_HUMAN with the residue 846 substituted with Phosphoserine" [UniProtKB:O15014] xref: UniProtKB:O15014 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0063330 ! ZN609_HUMAN [Term] id: CCO:B0072183 name: ZN609_HUMAN-Phosphoserine849 def: "Protein ZN609_HUMAN with the residue 849 substituted with Phosphoserine" [UniProtKB:O15014] xref: UniProtKB:O15014 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063330 ! ZN609_HUMAN [Term] id: CCO:B0072184 name: ZN615_HUMAN-Phosphoserine79 def: "Protein ZN615_HUMAN with the residue 79 substituted with Phosphoserine" [UniProtKB:Q8N8J6] xref: UniProtKB:Q8N8J6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057522 ! ZN615_HUMAN [Term] id: CCO:B0072185 name: ZN618_HUMAN-Phosphoserine16 def: "Protein ZN618_HUMAN with the residue 16 substituted with Phosphoserine" [UniProtKB:Q5T7W0] xref: UniProtKB:Q5T7W0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_function CCO:F0006300 ! protein dimerization activity relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056595 ! ZN618_HUMAN [Term] id: CCO:B0072186 name: ZN638_HUMAN-Phosphoserine128 def: "Protein ZN638_HUMAN with the residue 128 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072187 name: ZN638_HUMAN-Phosphoserine383 def: "Protein ZN638_HUMAN with the residue 383 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072188 name: ZN638_HUMAN-Phosphoserine420 def: "Protein ZN638_HUMAN with the residue 420 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072189 name: ZN638_HUMAN-Phosphoserine508 def: "Protein ZN638_HUMAN with the residue 508 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072190 name: ZN638_HUMAN-Phosphoserine510 def: "Protein ZN638_HUMAN with the residue 510 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072191 name: ZN638_HUMAN-Phosphoserine520 def: "Protein ZN638_HUMAN with the residue 520 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072192 name: ZN638_HUMAN-Phosphoserine522 def: "Protein ZN638_HUMAN with the residue 522 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072193 name: ZN638_HUMAN-Phosphoserine552 def: "Protein ZN638_HUMAN with the residue 552 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072194 name: ZN638_HUMAN-Phosphoserine558 def: "Protein ZN638_HUMAN with the residue 558 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072195 name: ZN638_HUMAN-Phosphoserine560 def: "Protein ZN638_HUMAN with the residue 560 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072196 name: ZN638_HUMAN-Phosphoserine605 def: "Protein ZN638_HUMAN with the residue 605 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0000282 ! double-stranded DNA binding relationship: has_function CCO:F0000308 ! RNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000262 ! nucleoplasm relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000820 ! nuclear speck relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072197 name: ZN638_HUMAN-Phosphoserine1100 def: "Protein ZN638_HUMAN with the residue 1100 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072198 name: ZN638_HUMAN-Phosphoserine1401 def: "Protein ZN638_HUMAN with the residue 1401 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072199 name: ZN638_HUMAN-Phosphoserine1825 def: "Protein ZN638_HUMAN with the residue 1825 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072200 name: ZN638_HUMAN-Phosphoserine1882 def: "Protein ZN638_HUMAN with the residue 1882 substituted with Phosphoserine" [UniProtKB:Q14966] xref: UniProtKB:Q14966 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:B0072201 name: ZN639_HUMAN-Phosphotyrosine4 def: "Protein ZN639_HUMAN with the residue 4 substituted with Phosphotyrosine" [UniProtKB:Q9UID6] xref: UniProtKB:Q9UID6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059156 ! ZN639_HUMAN [Term] id: CCO:B0072202 name: ZN644_HUMAN-Phosphoserine309 def: "Protein ZN644_HUMAN with the residue 309 substituted with Phosphoserine" [UniProtKB:Q9H582] xref: UniProtKB:Q9H582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058723 ! ZN644_HUMAN [Term] id: CCO:B0072203 name: ZN644_HUMAN-Phosphoserine1000 def: "Protein ZN644_HUMAN with the residue 1000 substituted with Phosphoserine" [UniProtKB:Q9H582] xref: UniProtKB:Q9H582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058723 ! ZN644_HUMAN [Term] id: CCO:B0072204 name: ZN644_HUMAN-Phosphoserine1189 def: "Protein ZN644_HUMAN with the residue 1189 substituted with Phosphoserine" [UniProtKB:Q9H582] xref: UniProtKB:Q9H582 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058723 ! ZN644_HUMAN [Term] id: CCO:B0072205 name: ZN648_HUMAN-Phosphoserine461 def: "Protein ZN648_HUMAN with the residue 461 substituted with Phosphoserine" [UniProtKB:Q5T619] xref: UniProtKB:Q5T619 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056587 ! ZN648_HUMAN [Term] id: CCO:B0072206 name: ZN652_HUMAN-Phosphoserine204 def: "Protein ZN652_HUMAN with the residue 204 substituted with Phosphoserine" [UniProtKB:Q9Y2D9] xref: UniProtKB:Q9Y2D9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059300 ! ZN652_HUMAN [Term] id: CCO:B0072207 name: ZN652_HUMAN-Phosphoserine380 def: "Protein ZN652_HUMAN with the residue 380 substituted with Phosphoserine" [UniProtKB:Q9Y2D9] xref: UniProtKB:Q9Y2D9 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0059300 ! ZN652_HUMAN [Term] id: CCO:B0072208 name: ZN654_HUMAN-Phosphoserine576 def: "Protein ZN654_HUMAN with the residue 576 substituted with Phosphoserine" [UniProtKB:Q8IZM8] comment: By similarity xref: UniProtKB:Q8IZM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057410 ! ZN654_HUMAN [Term] id: CCO:B0072209 name: ZN654_HUMAN-Phosphoserine580 def: "Protein ZN654_HUMAN with the residue 580 substituted with Phosphoserine" [UniProtKB:Q8IZM8] comment: By similarity xref: UniProtKB:Q8IZM8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057410 ! ZN654_HUMAN [Term] id: CCO:B0072210 name: ZN665_HUMAN-Phosphotyrosine97 def: "Protein ZN665_HUMAN with the residue 97 substituted with Phosphotyrosine" [UniProtKB:Q9H7R5] xref: UniProtKB:Q9H7R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058745 ! ZN665_HUMAN [Term] id: CCO:B0072211 name: ZN665_HUMAN-Phosphotyrosine99 def: "Protein ZN665_HUMAN with the residue 99 substituted with Phosphotyrosine" [UniProtKB:Q9H7R5] xref: UniProtKB:Q9H7R5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058745 ! ZN665_HUMAN [Term] id: CCO:B0072212 name: ZN670_HUMAN-Phosphotyrosine281 def: "Protein ZN670_HUMAN with the residue 281 substituted with Phosphotyrosine" [UniProtKB:Q9BS34] xref: UniProtKB:Q9BS34 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058504 ! ZN670_HUMAN [Term] id: CCO:B0072213 name: ZN687_HUMAN-Phosphoserine140 def: "Protein ZN687_HUMAN with the residue 140 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072214 name: ZN687_HUMAN-Phosphoserine253 def: "Protein ZN687_HUMAN with the residue 253 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072215 name: ZN687_HUMAN-Phosphoserine266 def: "Protein ZN687_HUMAN with the residue 266 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072216 name: ZN687_HUMAN-Phosphoserine271 def: "Protein ZN687_HUMAN with the residue 271 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072217 name: ZN687_HUMAN-Phosphoserine433 def: "Protein ZN687_HUMAN with the residue 433 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072218 name: ZN687_HUMAN-Phosphothreonine900 def: "Protein ZN687_HUMAN with the residue 900 substituted with Phosphothreonine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072219 name: ZN687_HUMAN-Phosphoserine1057 def: "Protein ZN687_HUMAN with the residue 1057 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072220 name: ZN687_HUMAN-Phosphoserine1082 def: "Protein ZN687_HUMAN with the residue 1082 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072221 name: ZN687_HUMAN-Phosphoserine1083 def: "Protein ZN687_HUMAN with the residue 1083 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072222 name: ZN687_HUMAN-Phosphoserine1085 def: "Protein ZN687_HUMAN with the residue 1085 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072223 name: ZN687_HUMAN-Phosphoserine1184 def: "Protein ZN687_HUMAN with the residue 1184 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072224 name: ZN687_HUMAN-Phosphoserine1191 def: "Protein ZN687_HUMAN with the residue 1191 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072225 name: ZN687_HUMAN-Phosphoserine1211 def: "Protein ZN687_HUMAN with the residue 1211 substituted with Phosphoserine" [UniProtKB:Q8N1G0] xref: UniProtKB:Q8N1G0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057427 ! ZN687_HUMAN [Term] id: CCO:B0072226 name: ZN711_HUMAN-Phosphoserine210 def: "Protein ZN711_HUMAN with the residue 210 substituted with Phosphoserine" [UniProtKB:Q9Y462] xref: UniProtKB:Q9Y462 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059348 ! ZN711_HUMAN [Term] id: CCO:B0072227 name: ZN717_HUMAN-Phosphoserine391 def: "Protein ZN717_HUMAN with the residue 391 substituted with Phosphoserine" [UniProtKB:Q9BY31] xref: UniProtKB:Q9BY31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058568 ! ZN717_HUMAN [Term] id: CCO:B0072228 name: ZN717_HUMAN-Phosphothreonine396 def: "Protein ZN717_HUMAN with the residue 396 substituted with Phosphothreonine" [UniProtKB:Q9BY31] xref: UniProtKB:Q9BY31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058568 ! ZN717_HUMAN [Term] id: CCO:B0072229 name: ZN717_HUMAN-Phosphoserine398 def: "Protein ZN717_HUMAN with the residue 398 substituted with Phosphoserine" [UniProtKB:Q9BY31] xref: UniProtKB:Q9BY31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058568 ! ZN717_HUMAN [Term] id: CCO:B0072230 name: ZN717_HUMAN-Phosphotyrosine402 def: "Protein ZN717_HUMAN with the residue 402 substituted with Phosphotyrosine" [UniProtKB:Q9BY31] xref: UniProtKB:Q9BY31 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058568 ! ZN717_HUMAN [Term] id: CCO:B0072231 name: ZN740_HUMAN-Phosphoserine44 def: "Protein ZN740_HUMAN with the residue 44 substituted with Phosphoserine" [UniProtKB:Q8NDX6] xref: UniProtKB:Q8NDX6 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057585 ! ZN740_HUMAN [Term] id: CCO:B0072232 name: ZN768_HUMAN-Phosphoserine17 def: "Protein ZN768_HUMAN with the residue 17 substituted with Phosphoserine" [UniProtKB:Q9H5H4] xref: UniProtKB:Q9H5H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058725 ! ZN768_HUMAN [Term] id: CCO:B0072233 name: ZN768_HUMAN-Phosphoserine18 def: "Protein ZN768_HUMAN with the residue 18 substituted with Phosphoserine" [UniProtKB:Q9H5H4] xref: UniProtKB:Q9H5H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000270 ! DNA-directed RNA polymerase II, core complex relationship: transformation_of CCO:B0058725 ! ZN768_HUMAN [Term] id: CCO:B0072234 name: ZN768_HUMAN-Phosphoserine83 def: "Protein ZN768_HUMAN with the residue 83 substituted with Phosphoserine" [UniProtKB:Q9H5H4] xref: UniProtKB:Q9H5H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058725 ! ZN768_HUMAN [Term] id: CCO:B0072235 name: ZN768_HUMAN-Phosphoserine97 def: "Protein ZN768_HUMAN with the residue 97 substituted with Phosphoserine" [UniProtKB:Q9H5H4] xref: UniProtKB:Q9H5H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058725 ! ZN768_HUMAN [Term] id: CCO:B0072236 name: ZN768_HUMAN-Phosphoserine125 def: "Protein ZN768_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q9H5H4] xref: UniProtKB:Q9H5H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058725 ! ZN768_HUMAN [Term] id: CCO:B0072237 name: ZN768_HUMAN-Phosphoserine295 def: "Protein ZN768_HUMAN with the residue 295 substituted with Phosphoserine" [UniProtKB:Q9H5H4] xref: UniProtKB:Q9H5H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058725 ! ZN768_HUMAN [Term] id: CCO:B0072238 name: ZN768_HUMAN-Phosphoserine299 def: "Protein ZN768_HUMAN with the residue 299 substituted with Phosphoserine" [UniProtKB:Q9H5H4] xref: UniProtKB:Q9H5H4 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0058725 ! ZN768_HUMAN [Term] id: CCO:B0072239 name: ZN775_HUMAN-Phosphothreonine304 def: "Protein ZN775_HUMAN with the residue 304 substituted with Phosphothreonine" [UniProtKB:Q96BV0] xref: UniProtKB:Q96BV0 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0058171 ! ZN775_HUMAN [Term] id: CCO:B0072240 name: ZN777_HUMAN-Phosphoserine554 def: "Protein ZN777_HUMAN with the residue 554 substituted with Phosphoserine" [UniProtKB:Q9ULD5] xref: UniProtKB:Q9ULD5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0059222 ! ZN777_HUMAN [Term] id: CCO:B0072241 name: ZN787_HUMAN-Phosphoserine104 def: "Protein ZN787_HUMAN with the residue 104 substituted with Phosphoserine" [UniProtKB:Q6DD87] xref: UniProtKB:Q6DD87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056723 ! ZN787_HUMAN [Term] id: CCO:B0072242 name: ZN787_HUMAN-Phosphothreonine117 def: "Protein ZN787_HUMAN with the residue 117 substituted with Phosphothreonine" [UniProtKB:Q6DD87] xref: UniProtKB:Q6DD87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056723 ! ZN787_HUMAN [Term] id: CCO:B0072243 name: ZN787_HUMAN-Phosphotyrosine122 def: "Protein ZN787_HUMAN with the residue 122 substituted with Phosphotyrosine" [UniProtKB:Q6DD87] xref: UniProtKB:Q6DD87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056723 ! ZN787_HUMAN [Term] id: CCO:B0072244 name: ZN787_HUMAN-Phosphotyrosine150 def: "Protein ZN787_HUMAN with the residue 150 substituted with Phosphotyrosine" [UniProtKB:Q6DD87] xref: UniProtKB:Q6DD87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056723 ! ZN787_HUMAN [Term] id: CCO:B0072245 name: ZN787_HUMAN-Phosphoserine171 def: "Protein ZN787_HUMAN with the residue 171 substituted with Phosphoserine" [UniProtKB:Q6DD87] xref: UniProtKB:Q6DD87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056723 ! ZN787_HUMAN [Term] id: CCO:B0072246 name: ZN787_HUMAN-Phosphoserine173 def: "Protein ZN787_HUMAN with the residue 173 substituted with Phosphoserine" [UniProtKB:Q6DD87] xref: UniProtKB:Q6DD87 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056723 ! ZN787_HUMAN [Term] id: CCO:B0072247 name: ZN800_HUMAN-Phosphoserine317 def: "Protein ZN800_HUMAN with the residue 317 substituted with Phosphoserine" [UniProtKB:Q2TB10] xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072248 name: ZN800_HUMAN-Phosphothreonine319 def: "Protein ZN800_HUMAN with the residue 319 substituted with Phosphothreonine" [UniProtKB:Q2TB10] xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072249 name: ZN800_HUMAN-Phosphoserine334 def: "Protein ZN800_HUMAN with the residue 334 substituted with Phosphoserine" [UniProtKB:Q2TB10] xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072250 name: ZN800_HUMAN-Phosphoserine336 def: "Protein ZN800_HUMAN with the residue 336 substituted with Phosphoserine" [UniProtKB:Q2TB10] xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072251 name: ZN800_HUMAN-Phosphoserine422 def: "Protein ZN800_HUMAN with the residue 422 substituted with Phosphoserine" [UniProtKB:Q2TB10] comment: By similarity xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072252 name: ZN800_HUMAN-Phosphoserine455 def: "Protein ZN800_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:Q2TB10] xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072253 name: ZN800_HUMAN-Phosphoserine457 def: "Protein ZN800_HUMAN with the residue 457 substituted with Phosphoserine" [UniProtKB:Q2TB10] xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072254 name: ZN800_HUMAN-Phosphoserine462 def: "Protein ZN800_HUMAN with the residue 462 substituted with Phosphoserine" [UniProtKB:Q2TB10] xref: UniProtKB:Q2TB10 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056229 ! ZN800_HUMAN [Term] id: CCO:B0072255 name: ZN846_HUMAN-Phosphoserine98 def: "Protein ZN846_HUMAN with the residue 98 substituted with Phosphoserine" [UniProtKB:Q147U1] xref: UniProtKB:Q147U1 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0056015 ! ZN846_HUMAN [Term] id: CCO:B0072256 name: ZNF44_HUMAN-Phosphoserine427 def: "Protein ZNF44_HUMAN with the residue 427 substituted with Phosphoserine" [UniProtKB:P15621] xref: UniProtKB:P15621 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055040 ! ZNF44_HUMAN [Term] id: CCO:B0072257 name: ZNF8_HUMAN-Phosphoserine355 def: "Protein ZNF8_HUMAN with the residue 355 substituted with Phosphoserine" [UniProtKB:P17098] xref: UniProtKB:P17098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055083 ! ZNF8_HUMAN [Term] id: CCO:B0072258 name: ZNF8_HUMAN-Phosphoserine455 def: "Protein ZNF8_HUMAN with the residue 455 substituted with Phosphoserine" [UniProtKB:P17098] xref: UniProtKB:P17098 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0000274 ! DNA binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055083 ! ZNF8_HUMAN [Term] id: CCO:B0072259 name: ZNHI3_HUMAN-Phosphoserine80 def: "Protein ZNHI3_HUMAN with the residue 80 substituted with Phosphoserine" [UniProtKB:Q15649] xref: UniProtKB:Q15649 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0056091 ! ZNHI3_HUMAN [Term] id: CCO:B0072260 name: ZO1_HUMAN-Phosphoserine125 def: "Protein ZO1_HUMAN with the residue 125 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072261 name: ZO1_HUMAN-Phosphoserine131 def: "Protein ZO1_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072262 name: ZO1_HUMAN-Phosphotyrosine132 def: "Protein ZO1_HUMAN with the residue 132 substituted with Phosphotyrosine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072263 name: ZO1_HUMAN-Phosphoserine329 def: "Protein ZO1_HUMAN with the residue 329 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072264 name: ZO1_HUMAN-Phosphoserine912 def: "Protein ZO1_HUMAN with the residue 912 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072265 name: ZO1_HUMAN-Phosphoserine927 def: "Protein ZO1_HUMAN with the residue 927 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072266 name: ZO1_HUMAN-Phosphoserine968 def: "Protein ZO1_HUMAN with the residue 968 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072267 name: ZO1_HUMAN-Phosphotyrosine1140 def: "Protein ZO1_HUMAN with the residue 1140 substituted with Phosphotyrosine" [UniProtKB:Q07157] comment: By similarity xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072268 name: ZO1_HUMAN-Phosphotyrosine1354 def: "Protein ZO1_HUMAN with the residue 1354 substituted with Phosphotyrosine" [UniProtKB:Q07157] comment: By similarity xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072269 name: ZO1_HUMAN-Phosphoserine1545 def: "Protein ZO1_HUMAN with the residue 1545 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072270 name: ZO1_HUMAN-Phosphoserine1617 def: "Protein ZO1_HUMAN with the residue 1617 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072271 name: ZO1_HUMAN-Phosphoserine1619 def: "Protein ZO1_HUMAN with the residue 1619 substituted with Phosphoserine" [UniProtKB:Q07157] xref: UniProtKB:Q07157 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:B0072272 name: ZO3_HUMAN-Phosphoserine159 def: "Protein ZO3_HUMAN with the residue 159 substituted with Phosphoserine" [UniProtKB:O95049] comment: By similarity xref: UniProtKB:O95049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063291 ! ZO3_HUMAN [Term] id: CCO:B0072273 name: ZO3_HUMAN-Phosphoserine164 def: "Protein ZO3_HUMAN with the residue 164 substituted with Phosphoserine" [UniProtKB:O95049] comment: By similarity xref: UniProtKB:O95049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063291 ! ZO3_HUMAN [Term] id: CCO:B0072274 name: ZO3_HUMAN-Phosphoserine169 def: "Protein ZO3_HUMAN with the residue 169 substituted with Phosphoserine" [UniProtKB:O95049] comment: By similarity xref: UniProtKB:O95049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063291 ! ZO3_HUMAN [Term] id: CCO:B0072275 name: ZO3_HUMAN-Phosphoserine579 def: "Protein ZO3_HUMAN with the residue 579 substituted with Phosphoserine" [UniProtKB:O95049] comment: By similarity xref: UniProtKB:O95049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000475 ! tight junction relationship: located_in CCO:C0000766 ! membrane relationship: located_in CCO:C0000936 ! cell junction relationship: transformation_of CCO:B0063291 ! ZO3_HUMAN [Term] id: CCO:B0072276 name: ZO3_HUMAN-Phosphoserine919 def: "Protein ZO3_HUMAN with the residue 919 substituted with Phosphoserine" [UniProtKB:O95049] comment: By similarity xref: UniProtKB:O95049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063291 ! ZO3_HUMAN [Term] id: CCO:B0072277 name: ZO3_HUMAN-Phosphoserine920 def: "Protein ZO3_HUMAN with the residue 920 substituted with Phosphoserine" [UniProtKB:O95049] comment: By similarity xref: UniProtKB:O95049 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0063291 ! ZO3_HUMAN [Term] id: CCO:B0072278 name: ZSC22_HUMAN-Phosphoserine32 def: "Protein ZSC22_HUMAN with the residue 32 substituted with Phosphoserine" [UniProtKB:P10073] xref: UniProtKB:P10073 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0054967 ! ZSC22_HUMAN [Term] id: CCO:B0072279 name: ZSC29_HUMAN-Phosphoserine560 def: "Protein ZSC29_HUMAN with the residue 560 substituted with Phosphoserine" [UniProtKB:Q8IWY8] xref: UniProtKB:Q8IWY8 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057366 ! ZSC29_HUMAN [Term] id: CCO:B0072280 name: ZXDA_HUMAN-Phosphoserine34 def: "Protein ZXDA_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P98168] xref: UniProtKB:P98168 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0000272 ! molecular_function relationship: has_function CCO:F0000273 ! nucleic acid binding relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0005713 ! identical protein binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000242 ! intracellular relationship: located_in CCO:C0000252 ! nucleus relationship: transformation_of CCO:B0055672 ! ZXDA_HUMAN [Term] id: CCO:B0072281 name: ZXDB_HUMAN-Phosphoserine34 def: "Protein ZXDB_HUMAN with the residue 34 substituted with Phosphoserine" [UniProtKB:P98169] comment: By similarity xref: UniProtKB:P98169 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0055673 ! ZXDB_HUMAN [Term] id: CCO:B0072282 name: ZYX_HUMAN-Phosphoserine169 def: "Protein ZYX_HUMAN with the residue 169 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0072283 name: ZYX_HUMAN-Phosphothreonine270 def: "Protein ZYX_HUMAN with the residue 270 substituted with Phosphothreonine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_function CCO:F0001646 ! protein binding relationship: has_function CCO:F0001810 ! zinc ion binding relationship: has_function CCO:F0006257 ! metal ion binding relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: located_in CCO:C0000180 ! stress fiber relationship: located_in CCO:C0000252 ! nucleus relationship: located_in CCO:C0000324 ! cytoplasm relationship: located_in CCO:C0000421 ! cytoskeleton relationship: located_in CCO:C0000444 ! plasma membrane relationship: located_in CCO:C0000445 ! integral to plasma membrane relationship: located_in CCO:C0000465 ! cell-cell adherens junction relationship: located_in CCO:C0000477 ! focal adhesion relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0072284 name: ZYX_HUMAN-Phosphothreonine274 def: "Protein ZYX_HUMAN with the residue 274 substituted with Phosphothreonine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0072285 name: ZYX_HUMAN-Phosphoserine288 def: "Protein ZYX_HUMAN with the residue 288 substituted with Phosphoserine" [UniProtKB:Q15942] xref: UniProtKB:Q15942 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:B0072286 name: ZZZ3_HUMAN-Phosphoserine130 def: "Protein ZZZ3_HUMAN with the residue 130 substituted with Phosphoserine" [UniProtKB:Q8IYH5] xref: UniProtKB:Q8IYH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057387 ! ZZZ3_HUMAN [Term] id: CCO:B0072287 name: ZZZ3_HUMAN-Phosphoserine131 def: "Protein ZZZ3_HUMAN with the residue 131 substituted with Phosphoserine" [UniProtKB:Q8IYH5] xref: UniProtKB:Q8IYH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057387 ! ZZZ3_HUMAN [Term] id: CCO:B0072288 name: ZZZ3_HUMAN-Phosphoserine135 def: "Protein ZZZ3_HUMAN with the residue 135 substituted with Phosphoserine" [UniProtKB:Q8IYH5] xref: UniProtKB:Q8IYH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057387 ! ZZZ3_HUMAN [Term] id: CCO:B0072289 name: ZZZ3_HUMAN-Phosphoserine474 def: "Protein ZZZ3_HUMAN with the residue 474 substituted with Phosphoserine" [UniProtKB:Q8IYH5] xref: UniProtKB:Q8IYH5 is_a: CCO:U0000011 ! cell cycle modified protein relationship: has_source CCO:T0000004 ! Homo sapiens organism relationship: transformation_of CCO:B0057387 ! ZZZ3_HUMAN [Term] id: CCO:C0000001 name: phosphopyruvate hydratase complex namespace: cellular_component def: "A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "enolase complex" EXACT [] xref: GO:0000015 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0005779 ! ENOA_HUMAN relationship: location_of CCO:B0006270 ! ENOG_HUMAN [Term] id: CCO:C0000002 name: repairosome namespace: cellular_component def: "A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of nucleotide excision repair (NER), such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage." [PMID:10681587, PMID:9852079] xref: GO:0000108 is_a: CCO:C0000003 ! nucleotide-excision repair complex [Term] id: CCO:C0000003 name: nucleotide-excision repair complex namespace: cellular_component def: "Any complex formed of proteins that act in nucleotide-excision repair." [PMID:10915862] comment: Note that process information is included in the term and definition for the purpose of describing and distinguishing the complex. subset: goslim_pir xref: GO:0000109 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0015646 ! ERCC1_HUMAN relationship: location_of CCO:B0055887 ! ERCC8_HUMAN [Term] id: CCO:C0000004 name: nucleotide-excision repair factor 1 complex namespace: cellular_component def: "One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p." [PMID:10915862] comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. synonym: "NEF1 complex" EXACT [] xref: GO:0000110 is_a: CCO:C0000003 ! nucleotide-excision repair complex [Term] id: CCO:C0000005 name: nucleotide-excision repair factor 2 complex namespace: cellular_component def: "One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p." [PMID:10915862] comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. synonym: "NEF2 complex" EXACT [] xref: GO:0000111 is_a: CCO:C0000003 ! nucleotide-excision repair complex [Term] id: CCO:C0000006 name: nucleotide-excision repair factor 3 complex namespace: cellular_component def: "One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (Core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, and Tfb4p. Note that Ssl2p is also called Rad25p)." [PMID:10915862, PMID:14500720, PMID:7813015] comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. synonym: "NEF3 complex" EXACT [] xref: GO:0000112 is_a: CCO:C0000003 ! nucleotide-excision repair complex [Term] id: CCO:C0000007 name: nucleotide-excision repair factor 4 complex namespace: cellular_component def: "One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p." [PMID:10915862] comment: Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex. synonym: "NEF4 complex" EXACT [] xref: GO:0000113 is_a: CCO:C0000003 ! nucleotide-excision repair complex [Term] id: CCO:C0000008 name: histone deacetylase complex namespace: cellular_component def: "A protein complex that possesses histone deacetylase activity." [GOC:mah] comment: Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone deacetylase activity ; GO:0004407'. synonym: "HDAC complex" EXACT [] xref: GO:0000118 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0001376 ! HDAC3_HUMAN relationship: location_of CCO:B0002002 ! HDAC7_HUMAN relationship: location_of CCO:B0005341 ! HDA10_HUMAN relationship: location_of CCO:B0005701 ! HDA11_HUMAN relationship: location_of CCO:B0006113 ! SAP18_HUMAN relationship: location_of CCO:B0012158 ! HDAC1_HUMAN-Phosphoserine423 relationship: location_of CCO:B0012159 ! HDAC2_HUMAN-Phosphoserine394 relationship: location_of CCO:B0012164 ! HDAC4_HUMAN-Phosphoserine467 relationship: location_of CCO:B0012166 ! HDAC5_HUMAN-Phosphoserine259 relationship: location_of CCO:B0012168 ! HDAC6_HUMAN-Phosphoserine22 relationship: location_of CCO:B0012174 ! HDAC9_HUMAN-Phosphoserine451 relationship: location_of CCO:B0023501 ! TAF6L_HUMAN relationship: location_of CCO:B0058162 ! PF21A_HUMAN relationship: location_of CCO:B0058569 ! HDAC8_HUMAN relationship: location_of CCO:B0064360 ! CIR_HUMAN-Phosphoserine202 relationship: location_of CCO:B0068312 ! MTA2_HUMAN-Phosphoserine57 relationship: location_of CCO:B0068837 ! NRIP1_HUMAN-Phosphoserine104 relationship: location_of CCO:B0070317 ! SAP30_HUMAN-Phosphoserine138 [Term] id: CCO:C0000009 name: mediator complex namespace: cellular_component def: "A protein complex that enables the RNA polymerase II-general RNA polymerase II transcription factor complex to react to transcriptional activator proteins; also enhances the level of basal transcription." [PMID:10384286, PMID:11114191, PMID:8187178, PMID:9396788, PMID:9774831] synonym: "S mediator complex" EXACT [] synonym: "TRAP complex" NARROW [] xref: GO:0000119 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0001627 ! CDK8_HUMAN relationship: location_of CCO:B0005277 ! MED4_HUMAN relationship: location_of CCO:B0005575 ! MED26_HUMAN relationship: location_of CCO:B0005783 ! MED21_HUMAN relationship: location_of CCO:B0005784 ! MED31_HUMAN relationship: location_of CCO:B0005787 ! MED18_HUMAN relationship: location_of CCO:B0005789 ! MED12_HUMAN relationship: location_of CCO:B0005791 ! MED16_HUMAN relationship: location_of CCO:B0005792 ! MED6_HUMAN relationship: location_of CCO:B0005795 ! MED22_HUMAN relationship: location_of CCO:B0005796 ! MED11_HUMAN relationship: location_of CCO:B0005797 ! MED30_HUMAN relationship: location_of CCO:B0005798 ! MED8_HUMAN relationship: location_of CCO:B0005800 ! MED14_HUMAN relationship: location_of CCO:B0005801 ! MD13L_HUMAN relationship: location_of CCO:B0012890 ! MED17_HUMAN-Phosphoserine37 relationship: location_of CCO:B0012901 ! MED1_HUMAN-Phosphothreonine1032 relationship: location_of CCO:B0012906 ! MED24_HUMAN-Phosphoserine862 relationship: location_of CCO:B0068121 ! MED13_HUMAN-Phosphoserine537 relationship: location_of CCO:B0069499 ! PRGC2_HUMAN-Phosphoserine524 relationship: location_of CCO:B0069784 ! RBM14_HUMAN-Phosphothreonine572 relationship: location_of CCO:B0071518 ! TR150_HUMAN-Phosphoserine684 relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000010 name: RNA polymerase I transcription factor complex namespace: cellular_component def: "A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase I." [GOC:mah] xref: GO:0000120 is_a: CCO:C0000272 ! transcription factor complex is_a: CCO:C0001871 ! nucleolar part relationship: location_of CCO:B0056075 ! TAF1A_HUMAN relationship: location_of CCO:B0070146 ! RPA34_HUMAN-Phosphotyrosine80 [Term] id: CCO:C0000011 name: histone acetyltransferase complex namespace: cellular_component def: "A protein complex that possesses histone acetyltransferase activity." [GOC:mah] comment: Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone acetyltransferase activity ; GO:0004402'. synonym: "histone acetylase complex" EXACT [] xref: GO:0000123 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0001728 ! EP300_HUMAN relationship: location_of CCO:B0002019 ! PCAF_HUMAN relationship: location_of CCO:B0005647 ! GCNL2_HUMAN relationship: location_of CCO:B0024549 ! Q4LE28_HUMAN relationship: location_of CCO:B0024552 ! O60424_HUMAN relationship: location_of CCO:B0064094 ! CBP_HUMAN-Phosphoserine121 [Term] id: CCO:C0000012 name: SAGA complex namespace: cellular_component def: "A large multiprotein complex that possesses histone acetyltransferase activity and is involved in regulation of transcription. The budding yeast complex includes Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins." [PMID:10637607] synonym: "Spt-Ada-Gcn5-acetyltransferase complex" EXACT [] xref: GO:0000124 is_a: CCO:C0000011 ! histone acetyltransferase complex relationship: location_of CCO:B0024005 ! UBP22_HUMAN [Term] id: CCO:C0000013 name: PCAF complex namespace: cellular_component def: "A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The composition is similar to that of the SAGA complex, but includes fewer Spt and Ada proteins, and more TAFs." [PMID:10637607] comment: See also the cellular component term 'SAGA complex ; GO:0000124'. xref: GO:0000125 is_a: CCO:C0000011 ! histone acetyltransferase complex relationship: location_of CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:C0000014 name: transcription factor TFIIIB complex namespace: cellular_component def: "A transcription factor for eukaryotic RNA polymerase III promoters that is an RNA polymerase binding protein." [GOC:mah, ISBN:0198547684] xref: GO:0000126 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0052829 ! TF3B_HUMAN-Phosphoserine433 [Term] id: CCO:C0000015 name: transcription factor TFIIIC complex namespace: cellular_component def: "A heterotrimeric transcription factor for eukaryotic RNA polymerase III promoters." [GOC:mah, ISBN:0198547684] xref: GO:0000127 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0071368 ! TF3C1_HUMAN-Phosphoserine1632 [Term] id: CCO:C0000016 name: incipient cellular bud site namespace: cellular_component def: "The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence." [GOC:clt] xref: GO:0000131 is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000017 name: polarisome namespace: cellular_component def: "Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p." [PMID:14734532, PMID:14998522, PMID:9632790] subset: goslim_pir xref: GO:0000133 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001867 ! cell cortex part relationship: location_of CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: part_of CCO:C0001007 ! site of polarized growth [Term] id: CCO:C0000018 name: alpha-1,6-mannosyltransferase complex namespace: cellular_component def: "A large, multiprotein complex with alpha-1,6 mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins." [GOC:mcc, PMID:10037752, PMID:11095735] xref: GO:0000136 is_a: CCO:C0001276 ! mannosyltransferase complex is_a: CCO:C0001850 ! Golgi apparatus part relationship: part_of CCO:C0000019 ! Golgi cis cisterna [Term] id: CCO:C0000019 name: Golgi cis cisterna namespace: cellular_component def: "The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER." [ISBN:0815316194] xref: GO:0000137 is_a: CCO:C0001377 ! Golgi cisterna relationship: location_of CCO:B0002175 ! NSMA2_HUMAN relationship: location_of CCO:B0058325 ! NECA3_HUMAN [Term] id: CCO:C0000020 name: Golgi trans cisterna namespace: cellular_component def: "The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed." [ISBN:0815316194] xref: GO:0000138 is_a: CCO:C0001377 ! Golgi cisterna relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN [Term] id: CCO:C0000021 name: Golgi membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." [GOC:mah] xref: GO:0000139 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0001466 ! RASN_HUMAN relationship: location_of CCO:B0001806 ! DHC24_HUMAN relationship: location_of CCO:B0001818 ! EXT1_HUMAN relationship: location_of CCO:B0002028 ! EXT2_HUMAN relationship: location_of CCO:B0002078 ! PMYT1_HUMAN relationship: location_of CCO:B0002175 ! NSMA2_HUMAN relationship: location_of CCO:B0005247 ! CHST1_HUMAN relationship: location_of CCO:B0005572 ! GNPTG_HUMAN relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0005706 ! M4K2_HUMAN relationship: location_of CCO:B0005950 ! BECN1_HUMAN relationship: location_of CCO:B0006164 ! STX5_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0010590 ! ARFG1_HUMAN-Phosphothreonine189 relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011921 ! GBF1_HUMAN-Phosphoserine1773 relationship: location_of CCO:B0011961 ! GORS2_HUMAN-Phosphothreonine225 relationship: location_of CCO:B0012444 ! JIP3_HUMAN-Phosphoserine365 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0015288 ! ARF1_HUMAN relationship: location_of CCO:B0026448 ! AT2C1_HUMAN relationship: location_of CCO:B0027593 ! CDIPT_HUMAN relationship: location_of CCO:B0031540 ! APC2_HUMAN relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0035594 ! RND3_HUMAN-Cysteine methyl ester241 relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0038854 ! FZD5_HUMAN relationship: location_of CCO:B0038991 ! CSTN1_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0041173 ! RASH_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0052399 ! GBRL2_HUMAN-Phosphoserine10 relationship: location_of CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: location_of CCO:B0054601 ! MTG16_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0054759 ! CNIH_HUMAN relationship: location_of CCO:B0054792 ! RAB36_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055356 ! NSG1_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055384 ! RPGP1_HUMAN relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055504 ! NDST2_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0055602 ! RAB2A_HUMAN relationship: location_of CCO:B0055660 ! COG7_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0057113 ! RHOU_HUMAN relationship: location_of CCO:B0057324 ! ZDH17_HUMAN relationship: location_of CCO:B0057878 ! B4GN2_HUMAN relationship: location_of CCO:B0057977 ! RAB2B_HUMAN relationship: location_of CCO:B0057978 ! CHPT1_HUMAN relationship: location_of CCO:B0058422 ! GPER_HUMAN relationship: location_of CCO:B0058512 ! NFIP1_HUMAN relationship: location_of CCO:B0058930 ! NFIP2_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059214 ! RAB21_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0059335 ! GOT1B_HUMAN relationship: location_of CCO:B0062770 ! ZDHC3_HUMAN relationship: location_of CCO:B0062835 ! Q8IV21_HUMAN relationship: location_of CCO:B0062929 ! MALL_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: location_of CCO:B0063024 ! COG5_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063139 ! GSLG1_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063322 ! ENTP6_HUMAN relationship: location_of CCO:B0063336 ! SIA7F_HUMAN relationship: location_of CCO:B0063384 ! MA2A2_HUMAN relationship: location_of CCO:B0063432 ! RER1_HUMAN relationship: location_of CCO:B0063733 ! BASI_HUMAN-Phosphoserine362 relationship: location_of CCO:B0063920 ! BIG2_HUMAN-Phosphoserine1514 relationship: location_of CCO:B0065672 ! AP3D1_HUMAN-Phosphoserine759 relationship: location_of CCO:B0065704 ! ARFG2_HUMAN-Phosphoserine498 relationship: location_of CCO:B0065705 ! ARFG3_HUMAN-Phosphoserine143 relationship: location_of CCO:B0065888 ! COG4_HUMAN-Phosphotyrosine714 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0066508 ! GOGB1_HUMAN-Phosphoserine17 relationship: location_of CCO:B0066552 ! GPSM1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0066584 ! GRB14_HUMAN-Phosphoserine372 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0069663 ! RAB12_HUMAN-Phosphoserine25 relationship: location_of CCO:B0069690 ! RAB6A_HUMAN-N-acetylserine2 relationship: location_of CCO:B0069693 ! RAB6B_HUMAN-Cysteine methyl ester208 relationship: location_of CCO:B0069759 ! RB33B_HUMAN-Cysteine methyl ester229 relationship: location_of CCO:B0069763 ! RB6I2_HUMAN-Phosphoserine17 relationship: location_of CCO:B0069839 ! RCAS1_HUMAN-Phosphothreonine41 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0070132 ! ROCK1_HUMAN-Phosphothreonine1180 relationship: location_of CCO:B0070283 ! S35B2_HUMAN-Phosphoserine427 relationship: location_of CCO:B0070338 ! SC16A_HUMAN-Phosphoserine1905 relationship: location_of CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 relationship: part_of CCO:C0000733 ! endomembrane system [Term] id: CCO:C0000022 name: cellular bud neck contractile ring namespace: cellular_component def: "A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis." [GOC:krc, PMID:16009555] synonym: "actomyosin ring (sensu Saccharomyces)" BROAD [] synonym: "contractile ring (sensu Saccharomyces)" EXACT [] synonym: "cytokinetic ring (sensu Saccharomyces)" BROAD [] synonym: "neck ring" EXACT [] xref: GO:0000142 is_a: CCO:C0000394 ! contractile ring relationship: part_of CCO:C0000487 ! cellular bud neck [Term] id: CCO:C0000023 name: cellular bud neck septin ring namespace: cellular_component def: "A ring-shaped structure that forms at the site of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange." [GOC:krc, PMID:16009555] synonym: "septin ring (sensu Saccharomyces)" EXACT [] xref: GO:0000144 is_a: CCO:C0000076 ! cellular bud neck septin structure is_a: CCO:C0000490 ! septin ring is_a: CCO:C0001410 ! cleavage apparatus septin structure [Term] id: CCO:C0000024 name: exocyst namespace: cellular_component def: "Protein complex peripherally associated with the plasma membrane that determines where secretory vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals." [PMID:9700152] xref: GO:0000145 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001867 ! cell cortex part relationship: location_of CCO:B0062769 ! EXOC7_HUMAN relationship: location_of CCO:B0065181 ! EXOC1_HUMAN-Phosphoserine470 relationship: location_of CCO:B0066032 ! EXOC4_HUMAN-Phosphothreonine237 [Term] id: CCO:C0000025 name: 1,3-beta-glucan synthase complex namespace: cellular_component def: "A protein complex that catalyzes the transfer of a glucose moiety from UDP-glucose to a 1,3-beta-D-glucan chain." [EC:2.4.1.34] xref: GO:0000148 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0000026 name: ubiquitin ligase complex namespace: cellular_component def: "A protein complex that includes a ubiquitin-protein ligase (E3) and other proteins that may confer substrate specificity on the complex." [PMID:9529603] subset: goslim_pir subset: gosubset_prok xref: GO:0000151 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0002086 ! BARD1_HUMAN relationship: location_of CCO:B0002252 ! SUGT1_HUMAN relationship: location_of CCO:B0005309 ! RNF37_HUMAN relationship: location_of CCO:B0005332 ! FBX11_HUMAN relationship: location_of CCO:B0005355 ! CAND1_HUMAN relationship: location_of CCO:B0005440 ! FBX25_HUMAN relationship: location_of CCO:B0005441 ! FBX4_HUMAN relationship: location_of CCO:B0005442 ! FBX7_HUMAN relationship: location_of CCO:B0005941 ! FBW1B_HUMAN relationship: location_of CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 relationship: location_of CCO:B0020553 ! RING1_HUMAN relationship: location_of CCO:B0032438 ! FBX8_HUMAN relationship: location_of CCO:B0042518 ! BRCC3_HUMAN relationship: location_of CCO:B0043431 ! FBXL7_HUMAN relationship: location_of CCO:B0055562 ! FBXW4_HUMAN relationship: location_of CCO:B0058653 ! WWP1_HUMAN relationship: location_of CCO:B0058768 ! SMUF2_HUMAN relationship: location_of CCO:B0059251 ! STUB1_HUMAN relationship: location_of CCO:B0062996 ! RNF11_HUMAN relationship: location_of CCO:B0064109 ! CBX8_HUMAN-Phosphoserine332 relationship: location_of CCO:B0067737 ! LMO7_HUMAN-Phosphoserine867 relationship: location_of CCO:B0069547 ! PRP19_HUMAN-Phosphothreonine342 relationship: location_of CCO:B0071528 ! TRAF7_HUMAN-Phosphoserine91 relationship: location_of CCO:B0071883 ! WWP2_HUMAN-Phosphoserine211 [Term] id: CCO:C0000027 name: nuclear ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex found in the nucleus." [GOC:mah] xref: GO:0000152 is_a: CCO:C0000026 ! ubiquitin ligase complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0005951 ! BRE_HUMAN relationship: location_of CCO:B0042518 ! BRCC3_HUMAN [Term] id: CCO:C0000028 name: cytoplasmic ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex found in the cytoplasm." [GOC:mah] xref: GO:0000153 is_a: CCO:C0000026 ! ubiquitin ligase complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000029 name: protein phosphatase type 2A complex namespace: cellular_component def: "A heterodimer with protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic and regulatory subunits." [GOC:mah, ISBN:0198547684] xref: GO:0000159 is_a: CCO:C0000541 ! protein serine/threonine phosphatase complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0002258 ! P2R3B_HUMAN relationship: location_of CCO:B0005518 ! 2A5E_HUMAN relationship: location_of CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0025635 ! PTPA_HUMAN relationship: location_of CCO:B0025990 ! 2A5B_HUMAN relationship: location_of CCO:B0025993 ! Q59EK0_HUMAN relationship: location_of CCO:B0025995 ! Q96B13_HUMAN relationship: location_of CCO:B0025996 ! Q6ZN33_HUMAN relationship: location_of CCO:B0026109 ! Q8NEC4_HUMAN relationship: location_of CCO:B0026111 ! 2ABD_HUMAN relationship: location_of CCO:B0026113 ! Q59GC6_HUMAN relationship: location_of CCO:B0026114 ! 2ABA_HUMAN relationship: location_of CCO:B0026115 ! Q56VW8_HUMAN relationship: location_of CCO:B0026116 ! 2ABB_HUMAN relationship: location_of CCO:B0026117 ! Q6ZP32_HUMAN relationship: location_of CCO:B0026121 ! 2ABG_HUMAN relationship: location_of CCO:B0026125 ! A6NEJ2_HUMAN relationship: location_of CCO:B0029136 ! A8MZB4_HUMAN relationship: location_of CCO:B0029137 ! A8MU22_HUMAN relationship: location_of CCO:B0029138 ! A8KAK0_HUMAN relationship: location_of CCO:B0029139 ! A8MSY7_HUMAN relationship: location_of CCO:B0029141 ! A8MW32_HUMAN relationship: location_of CCO:B0052260 ! 2A5G_HUMAN-Phosphotyrosine348 relationship: location_of CCO:B0056396 ! Q59G20_HUMAN relationship: location_of CCO:B0057243 ! Q86U13_HUMAN relationship: location_of CCO:B0058990 ! Q9NZ48_HUMAN relationship: location_of CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0065195 ! 2A5A_HUMAN-Phosphoserine42 relationship: location_of CCO:B0065196 ! 2A5D_HUMAN-Phosphoserine573 [Term] id: CCO:C0000030 name: protein phosphatase type 1 complex namespace: cellular_component def: "A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity." [GOC:mah, GOC:ssd] xref: GO:0000164 is_a: CCO:C0000541 ! protein serine/threonine phosphatase complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:C0000031 name: ribonuclease MRP complex namespace: cellular_component def: "A ribonucleoprotein complex that cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication." [GOC:sgd_curators, PMID:10690410, PMID:14729943, PMID:7510714] synonym: "ribonuclease mitochondrial RNA processing complex" EXACT [] synonym: "RNase MRP complex" EXACT [] xref: GO:0000172 is_a: CCO:C0000322 ! small nucleolar ribonucleoprotein complex [Term] id: CCO:C0000032 name: nuclear exosome (RNase complex) namespace: cellular_component def: "Complex of 3'-5' exoribonucleases found in the nucleus." [PMID:10465791] synonym: "eukaryotic exosome multienzyme ribonuclease complex" EXACT [] synonym: "nuclear exosome (ribonuclease complex)" EXACT [] synonym: "nuclear exosome multienzyme ribonuclease complex" EXACT [] xref: GO:0000176 is_a: CCO:C0000034 ! exosome (RNase complex) is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0005348 ! EXOSX_HUMAN relationship: location_of CCO:B0011810 ! EXOS3_HUMAN-N-acetylalanine2 [Term] id: CCO:C0000033 name: cytoplasmic exosome (RNase complex) namespace: cellular_component def: "Complex of 3'-5' exoribonucleases found in the cytoplasm." [PMID:10465791] synonym: "cytoplasmic exosome (ribonuclease complex)" EXACT [] synonym: "cytoplasmic exosome multienzyme ribonuclease complex" EXACT [] synonym: "prokaryotic exosome multienzyme ribonuclease complex" EXACT [] xref: GO:0000177 is_a: CCO:C0000034 ! exosome (RNase complex) is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0011810 ! EXOS3_HUMAN-N-acetylalanine2 [Term] id: CCO:C0000034 name: exosome (RNase complex) namespace: cellular_component def: "Complex of 3'-5' exoribonucleases." [PMID:10465791] comment: Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies. subset: goslim_pir synonym: "exosome (ribonucleasease complex)" EXACT [] synonym: "exosome multienzyme ribonuclease complex" EXACT [] xref: GO:0000178 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0005348 ! EXOSX_HUMAN relationship: location_of CCO:B0005556 ! EXOS8_HUMAN relationship: location_of CCO:B0011810 ! EXOS3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011811 ! EXOS4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011812 ! EXOS5_HUMAN-Phosphoserine20 relationship: location_of CCO:B0039762 ! EXOS2_HUMAN-Phosphotyrosine46 relationship: location_of CCO:B0055952 ! C1D_HUMAN [Term] id: CCO:C0000035 name: tRNA-intron endonuclease complex namespace: cellular_component def: "A complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron." [EC:3.1.27.9] xref: GO:0000214 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000036 name: vacuolar proton-transporting V-type ATPase, V0 domain namespace: cellular_component def: "The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane." [GOC:mah, PMID:16449553] comment: Note that this domain often consists of five subunits, although in some mammalian tissues it may have an additional subunit. synonym: "vacuolar hydrogen ion-transporting ATPase V0 domain" EXACT [] xref: GO:0000220 is_a: CCO:C0001549 ! proton-transporting V-type ATPase, V0 domain relationship: part_of CCO:C0000793 ! vacuolar proton-transporting V-type ATPase complex [Term] id: CCO:C0000037 name: vacuolar proton-transporting V-type ATPase, V1 domain namespace: cellular_component def: "The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane." [GOC:mah, PMID:16449553] comment: Note that this domain generally consists of eight subunits. synonym: "vacuolar hydrogen ion-transporting ATPase V1 domain" EXACT [] xref: GO:0000221 is_a: CCO:C0001550 ! proton-transporting V-type ATPase, V1 domain relationship: part_of CCO:C0000793 ! vacuolar proton-transporting V-type ATPase complex [Term] id: CCO:C0000038 name: plasma membrane proton-transporting V-type ATPase, V0 domain namespace: cellular_component def: "The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane." [GOC:mah] synonym: "plasma membrane hydrogen ion-transporting ATPase V0 domain" EXACT [] xref: GO:0000222 is_a: CCO:C0001549 ! proton-transporting V-type ATPase, V0 domain is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane relationship: part_of CCO:C0001551 ! plasma membrane proton-transporting V-type ATPase complex [Term] id: CCO:C0000039 name: plasma membrane proton-transporting V-type ATPase, V1 domain namespace: cellular_component def: "The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane." [GOC:mah] synonym: "plasma membrane hydrogen ion-transporting ATPase V1 domain" EXACT [] xref: GO:0000223 is_a: CCO:C0001550 ! proton-transporting V-type ATPase, V1 domain is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane relationship: part_of CCO:C0001551 ! plasma membrane proton-transporting V-type ATPase complex [Term] id: CCO:C0000040 name: nuclear chromosome namespace: cellular_component def: "A chromosome found in the nucleus of a eukaryotic cell." [GOC:mah] subset: goslim_generic synonym: "nuclear interphase chromosome" NARROW [] xref: GO:0000228 is_a: CCO:C0000296 ! chromosome is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001403 ! RAD21_HUMAN relationship: location_of CCO:B0001447 ! REC8_HUMAN relationship: location_of CCO:B0001450 ! SMC2_HUMAN relationship: location_of CCO:B0001732 ! SNF5_HUMAN relationship: location_of CCO:B0005231 ! ZBED1_HUMAN relationship: location_of CCO:B0005416 ! SMCE1_HUMAN relationship: location_of CCO:B0012449 ! JUN_HUMAN-Phosphoserine63 relationship: location_of CCO:B0014328 ! TE2IP_HUMAN-Phosphoserine154 relationship: location_of CCO:B0019996 ! Q9H836_HUMAN relationship: location_of CCO:B0036796 ! GBX1_HUMAN relationship: location_of CCO:B0050294 ! HMGB2_HUMAN relationship: location_of CCO:B0055291 ! HXD12_HUMAN relationship: location_of CCO:B0058456 ! PRRX2_HUMAN relationship: location_of CCO:B0058569 ! HDAC8_HUMAN relationship: location_of CCO:B0058792 ! BARX1_HUMAN relationship: location_of CCO:B0063748 ! BAZ1A_HUMAN-Phosphoserine1371 relationship: location_of CCO:B0069142 ! PB1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0072071 ! ZN238_HUMAN-Phosphoserine516 [Term] id: CCO:C0000041 name: cytoplasmic chromosome namespace: cellular_component def: "A chromosome found in the cytoplasm." [GOC:mah] subset: goslim_generic subset: gosubset_prok synonym: "cytoplasmic interphase chromosome" NARROW [] xref: GO:0000229 is_a: CCO:C0000296 ! chromosome is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000042 name: astral microtubule namespace: cellular_component def: "Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [ISBN:0815316194] xref: GO:0000235 is_a: CCO:C0000436 ! spindle microtubule is_a: CCO:C0000439 ! cytoplasmic microtubule relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: part_of CCO:C0000387 ! aster [Term] id: CCO:C0000043 name: pericentriolar material namespace: cellular_component def: "A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome." [GOC:clt, ISBN:0815316194] xref: GO:0000242 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: location_of CCO:B0001490 ! LCK_HUMAN relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0002211 ! TBE_HUMAN relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: part_of CCO:C0000383 ! centrosome [Term] id: CCO:C0000044 name: commitment complex namespace: cellular_component def: "The first portion of the spliceosome to assemble in mRNA splicing; in commitment complex formation the 5' and 3' splice sites are recognized by the U1 snRNP and the U2 snRNP auxiliary factor, respectively." [PMID:9159080] synonym: "E complex" EXACT [] xref: GO:0000243 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001847 ! nuclear part relationship: part_of CCO:C0000283 ! spliceosome [Term] id: CCO:C0000045 name: mitochondrial chromosome namespace: cellular_component def: "A chromosome found in the mitochondrion of a eukaryotic cell." [GOC:mah] synonym: "mitochondrial DNA" NARROW [] synonym: "mitochondrial genome" RELATED [] synonym: "mtDNA" NARROW [] xref: GO:0000262 is_a: CCO:C0000041 ! cytoplasmic chromosome is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0059145 ! DPOG2_HUMAN relationship: part_of CCO:C0001678 ! mitochondrial nucleoid [Term] id: CCO:C0000046 name: cell fraction namespace: cellular_component def: "A generic term for parts of cells prepared by disruptive biochemical techniques." [GOC:ma] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. subset: goslim_pir subset: gosubset_prok xref: GO:0000267 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0035355 ! PDE7A_HUMAN-Phosphoserine84 [Term] id: CCO:C0000047 name: mitochondrial proton-transporting ATP synthase, stator stalk namespace: cellular_component def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core." [GOC:mtg_sensu, PMID:10838056] synonym: "hydrogen-transporting ATP synthase, stator stalk (sensu Eukaryota)" EXACT [] synonym: "proton-transporting ATP synthase, stator stalk (sensu Eukaryota)" EXACT [] xref: GO:0000274 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001926 ! proton-transporting ATP synthase, stator stalk relationship: part_of CCO:C0000049 ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) [Term] id: CCO:C0000048 name: mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) namespace: cellular_component def: "The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled." [GOC:mtg_sensu, PMID:10838056] comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. synonym: "hydrogen-transporting ATP synthase, F1 sector" BROAD [] synonym: "proton-transporting ATP synthase complex, catalytic core F(1) (sensu Eukaryota)" EXACT [] xref: GO:0000275 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: part_of CCO:C0000337 ! mitochondrial proton-transporting ATP synthase complex [Term] id: CCO:C0000049 name: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) namespace: cellular_component def: "All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins." [GOC:mtg_sensu, PMID:10838056] synonym: "hydrogen-transporting ATP synthase, F0 sector" BROAD [] synonym: "proton-transporting ATP synthase complex, coupling factor F(0) (sensu Eukaryota)" EXACT [] synonym: "proton-transporting ATP synthase complex, coupling factor F(o) (sensu Eukaryota)" EXACT [] xref: GO:0000276 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001924 ! proton-transporting ATP synthase complex, coupling factor F(o) relationship: part_of CCO:C0000337 ! mitochondrial proton-transporting ATP synthase complex [Term] id: CCO:C0000050 name: integral to membrane of membrane fraction namespace: cellular_component def: "Integral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; require detergents, such as Triton X-100, to be released from membranes." [PMID:10512869] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. xref: GO:0000299 is_a: CCO:C0000244 ! membrane fraction relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0038263 ! ADA1B_HUMAN relationship: location_of CCO:B0055262 ! CD70_HUMAN relationship: location_of CCO:B0057916 ! CERK1_HUMAN relationship: location_of CCO:B0059206 ! AMFR2_HUMAN [Term] id: CCO:C0000051 name: peripheral to membrane of membrane fraction namespace: cellular_component def: "Peripheral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; can be extracted from membrane fraction with high concentrations of salt or high pH." [PMID:10512869] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. xref: GO:0000300 is_a: CCO:C0000244 ! membrane fraction relationship: location_of CCO:B0001455 ! RECK_HUMAN [Term] id: CCO:C0000052 name: extrinsic to vacuolar membrane namespace: cellular_component def: "Loosely bound to one or the other surface of the vacuolar membrane, but not integrated into the hydrophobic region." [GOC:jl, GOC:mah, http://cancerweb.ncl.ac.uk/] xref: GO:0000306 is_a: CCO:C0001199 ! extrinsic to organelle membrane is_a: CCO:C0001856 ! vacuolar part relationship: part_of CCO:C0000356 ! vacuolar membrane [Term] id: CCO:C0000053 name: cyclin-dependent protein kinase holoenzyme complex namespace: cellular_component def: "Cyclin-dependent protein kinases (CDKs) are heterodimeric enzymes that contain a kinase catalytic subunit associated with a regulatory cyclin partner." [GOC:krc, PMID:11602261] subset: goslim_pir synonym: "CDK holoenzyme" EXACT [] xref: GO:0000307 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001513 ! PCNA_HUMAN relationship: location_of CCO:B0001573 ! CCND2_HUMAN relationship: location_of CCO:B0001574 ! CCND3_HUMAN relationship: location_of CCO:B0001599 ! CDN1A_HUMAN relationship: location_of CCO:B0001708 ! CDK6_HUMAN relationship: location_of CCO:B0011105 ! CDK2_HUMAN-Phosphotyrosine19 relationship: location_of CCO:B0011112 ! CDK4_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0048182 ! CCND1_HUMAN-Phosphotyrosine226 [Term] id: CCO:C0000054 name: cytoplasmic cyclin-dependent protein kinase holoenzyme complex namespace: cellular_component def: "Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm." [GOC:krc] synonym: "CDK holoenzyme" BROAD [] xref: GO:0000308 is_a: CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000055 name: plastid large ribosomal subunit namespace: cellular_component def: "The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site)." [GOC:mcc] xref: GO:0000311 is_a: CCO:C0000059 ! organellar large ribosomal subunit is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000674 ! plastid ribosome [Term] id: CCO:C0000056 name: plastid small ribosomal subunit namespace: cellular_component def: "The smaller of the two subunits of a plastid ribosome." [GOC:mcc] xref: GO:0000312 is_a: CCO:C0000058 ! organellar small ribosomal subunit is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000674 ! plastid ribosome [Term] id: CCO:C0000057 name: organellar ribosome namespace: cellular_component def: "A ribosome contained within a subcellular organelle." [GOC:mcc] xref: GO:0000313 is_a: CCO:C0000407 ! ribosome [Term] id: CCO:C0000058 name: organellar small ribosomal subunit namespace: cellular_component def: "The smaller of the two subunits of an organellar ribosome." [GOC:mcc] xref: GO:0000314 is_a: CCO:C0000756 ! small ribosomal subunit relationship: part_of CCO:C0000057 ! organellar ribosome [Term] id: CCO:C0000059 name: organellar large ribosomal subunit namespace: cellular_component def: "The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site)." [GOC:mcc] xref: GO:0000315 is_a: CCO:C0000755 ! large ribosomal subunit relationship: part_of CCO:C0000057 ! organellar ribosome [Term] id: CCO:C0000060 name: storage vacuole namespace: cellular_component def: "A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules." [GOC:krc] xref: GO:0000322 is_a: CCO:C0000355 ! vacuole [Term] id: CCO:C0000061 name: lytic vacuole namespace: cellular_component def: "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases." [GOC:krc] xref: GO:0000323 is_a: CCO:C0000355 ! vacuole [Term] id: CCO:C0000064 name: protein storage vacuole namespace: cellular_component def: "A compound organelle of plants where there is a lytic vacuole within a storage vacuole." [PMID:11739409] xref: GO:0000326 is_a: CCO:C0000060 ! storage vacuole is_a: CCO:C0002152 ! plant-type vacuole [Term] id: CCO:C0000065 name: lytic vacuole within protein storage vacuole namespace: cellular_component def: "A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole." [PMID:11739490] xref: GO:0000327 is_a: CCO:C0000061 ! lytic vacuole is_a: CCO:C0000064 ! protein storage vacuole [Term] id: CCO:C0000069 name: contractile vacuole namespace: cellular_component def: "A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. Its function is probably osmoregulatory." [GOC:jl, http://cancerweb.ncl.ac.uk/, PMID:10503189] xref: GO:0000331 is_a: CCO:C0000355 ! vacuole [Term] id: CCO:C0000070 name: telomerase catalytic core complex namespace: cellular_component def: "The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition." [PMID:11884619] xref: GO:0000333 is_a: CCO:C0000297 ! telomerase holoenzyme complex [Term] id: CCO:C0000071 name: plastid-encoded plastid RNA polymerase complex A namespace: cellular_component def: "A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex." [PMID:10946105] synonym: "PEP-A" EXACT [] xref: GO:0000343 is_a: CCO:C0000084 ! plastid-encoded plastid RNA polymerase complex [Term] id: CCO:C0000072 name: plastid-encoded plastid RNA polymerase complex B namespace: cellular_component def: "A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation." [PMID:10946105] synonym: "PEP-B" EXACT [] xref: GO:0000344 is_a: CCO:C0000084 ! plastid-encoded plastid RNA polymerase complex [Term] id: CCO:C0000073 name: cytosolic DNA-directed RNA polymerase complex namespace: cellular_component def: "The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity." [PMID:11158566] subset: gosubset_prok synonym: "cytosolic DNA-directed RNA polymerase complex (sensu Bacteria)" EXACT [] xref: GO:0000345 is_a: CCO:C0000085 ! DNA-directed RNA polymerase complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0000074 name: transcription export complex namespace: cellular_component def: "The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans." [GOC:krc, PMID:11979277] subset: goslim_pir synonym: "TREX complex" EXACT [] xref: GO:0000346 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000075 name: THO complex namespace: cellular_component def: "The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits." [GOC:krc, PMID:11060033, PMID:11979277, PMID:16983072] subset: goslim_pir xref: GO:0000347 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000076 name: cellular bud neck septin structure namespace: cellular_component def: "Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle." [GOC:krc] xref: GO:0000399 is_a: CCO:C0001404 ! cell division site part relationship: part_of CCO:C0000487 ! cellular bud neck [Term] id: CCO:C0000077 name: pre-autophagosomal structure namespace: cellular_component def: "A punctate structure localized in the vicinity of the vacuole that is required for the formation of autophagosomes." [GOC:elh, PMID:11689437, PMID:12048214, PMID:12554655] synonym: "PAS" EXACT [] synonym: "perivacuolar space" NARROW [] synonym: "phagophore assembly site" RELATED [] xref: GO:0000407 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000078 name: EKC/KEOPS protein complex namespace: cellular_component def: "A protein complex proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p." [GOC:elh, PMID:16564010, PMID:16874308] synonym: "Endopeptidase-like Kinase Chromatin-associated protein complex" EXACT [] synonym: "Kinase, putative Endopeptidase and Other Proteins of Small size protein complex" EXACT [] xref: GO:0000408 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000079 name: HIR complex namespace: cellular_component def: "A protein complex proposed to be involved in replication-independent chromatin assembly. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p." [GOC:elh, PMID:16303565] xref: GO:0000417 is_a: CCO:C0000281 ! chromatin assembly complex [Term] id: CCO:C0000080 name: DNA-directed RNA polymerase IV complex namespace: cellular_component def: "RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The IVa and IVb complexes contain different forms of the largest subunit. The remainder of the complex is composed of smaller subunits." [GOC:krc, GOC:mtg_sensu, PMID:15692015, PMID:15766525, PMID:16140984] xref: GO:0000418 is_a: CCO:C0001870 ! nucleoplasm part is_a: CCO:C0002015 ! nuclear DNA-directed RNA polymerase complex [Term] id: CCO:C0000081 name: DNA-directed RNA polymerase IVb complex namespace: cellular_component def: "RNA polymerase IVb is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensu thes sequence as well as other sequences. The remainder of the complex is composed of smaller subunits." [GOC:krc, GOC:mtg_sensu, PMID:16140984] xref: GO:0000419 is_a: CCO:C0000080 ! DNA-directed RNA polymerase IV complex [Term] id: CCO:C0000082 name: DNA-directed RNA polymerase IVa complex namespace: cellular_component def: "RNA polymerase IVa is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVb, while the largest subunit is found only in the IVa complex. The remainder of the complex is composed of smaller subunits." [GOC:krc, GOC:mtg_sensu, PMID:15692015, PMID:15766525, PMID:16140984] xref: GO:0000420 is_a: CCO:C0000080 ! DNA-directed RNA polymerase IV complex [Term] id: CCO:C0000083 name: autophagic vacuole membrane namespace: cellular_component def: "The lipid bilayer surrounding an autophagic vacuole, a double-membrane bound vesicle in which endogenous cellular material is sequestered." [GOC:isa_complete] synonym: "autophagosome membrane" EXACT [] xref: GO:0000421 is_a: CCO:C0000356 ! vacuolar membrane relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0052399 ! GBRL2_HUMAN-Phosphoserine10 relationship: part_of CCO:C0000358 ! autophagic vacuole [Term] id: CCO:C0000084 name: plastid-encoded plastid RNA polymerase complex namespace: cellular_component def: "An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition." [GOC:krc, GOC:mah, GOC:pj] xref: GO:0000427 is_a: CCO:C0000085 ! DNA-directed RNA polymerase complex is_a: CCO:C0001854 ! plastid part [Term] id: CCO:C0000085 name: DNA-directed RNA polymerase complex namespace: cellular_component def: "A protein complex that possesses DNA-directed RNA polymerase activity." [GOC:krc] xref: GO:0000428 is_a: CCO:C0001068 ! RNA polymerase complex [Term] id: CCO:C0000086 name: core TFIIH complex portion of holo TFIIH complex namespace: cellular_component def: "The core TFIIH complex when it is part of the general transcription factor TFIIH. In S. cerevisiae, it is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p and Tfb4p. In humans, it is composed of XPD, p62, p55, p44, p34." [GOC:krc, PMID:14500720, PMID:7813015] xref: GO:0000438 is_a: CCO:C0000087 ! core TFIIH complex relationship: part_of CCO:C0000091 ! SSL2-core TFIIH complex portion of holo TFIIH complex [Term] id: CCO:C0000087 name: core TFIIH complex namespace: cellular_component def: "A complex that contains kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. In S. cerevisiae, it is composed of the 5-subunit core (Rad3p, Tfb1p, Tfb2p, Ssl1p and Tfb4p), Ssl2p, and TFIIK (Kin28p, Ccl1p, and Tfb3p). All of the subunits have equivalents in humans: the 5 subunit core is composed of XPD, p62, p55, p44, p34; the equivalent of the TFIIK subcomplex is composed of MO15, Mat1, and a cyclin; the human equivalent of Ssl2p is XPB." [GOC:krc, PMID:14500720, PMID:7813015] xref: GO:0000439 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0023973 ! TF2H3_HUMAN relationship: part_of CCO:C0000089 ! SSL2-core TFIIH complex [Term] id: CCO:C0000088 name: core TFIIH complex portion of NEF3 complex namespace: cellular_component def: "The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3). In S. cerevisiae, it is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, and Tfb4p. In humans, it is composed of XPD, p62, p55, p44, p34." [GOC:krc, PMID:14500720, PMID:7813015] xref: GO:0000440 is_a: CCO:C0000087 ! core TFIIH complex relationship: part_of CCO:C0000090 ! SSL2-core TFIIH complex portion of NEF3 complex [Term] id: CCO:C0000089 name: SSL2-core TFIIH complex namespace: cellular_component def: "A complex which is part of both the general transcription factor TFIIH and the nucleotide-excision repair factor 3 complex. It is composed of the tightly associated 5 subunit core TFIIH subcomplex plus one additional, more loosely associated subunit. The subunits are well conserved from yeast to humans. In S. cerevisiae, the 5-subunit core is composed of Rad3, Tfb1, Tfb2, Ssl1, Tfb4 and the loosely associated subunit is Ssl2p (also called Rad25). In humans, the 5 subunit core is composed of XPD, p62, p55, p44, p34 and the loosely associated subunit is XPB." [GOC:krc, PMID:14500720, PMID:7813015] subset: goslim_pir xref: GO:0000441 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000090 name: SSL2-core TFIIH complex portion of NEF3 complex namespace: cellular_component def: "The SSL2-core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3). It is composed of the tightly associated 5 subunit core TFIIH subcomplex plus one additional, less tighly associated subunit. The subunits are well conserved from yeast to humans. In S. cerevisiae, the 5-subunit core is composed of Rad3, Tfb1, Tfb2, Ssl1, Tfb4 and the loosely associated subunit is Ssl2p (also called Rad25). In humans, the 5 subunit core is composed of XPD, p62, p55, p44, p34 and the loosely associated subunit is XPB." [GOC:krc, PMID:14500720, PMID:7813015] xref: GO:0000442 is_a: CCO:C0000089 ! SSL2-core TFIIH complex relationship: part_of CCO:C0000006 ! nucleotide-excision repair factor 3 complex [Term] id: CCO:C0000091 name: SSL2-core TFIIH complex portion of holo TFIIH complex namespace: cellular_component def: "The SSL2-core TFIIH complex when it is part of the general transcription factor TFIIH. It is composed of the tightly associated five subunit core TFIIH subcomplex plus one additional, less tighly associated subunit. The subunits are well conserved from yeast to humans. In S. cerevisiae, the 5-subunit core is composed of Rad3, Tfb1, Tfb2, Ssl1, Tfb4 and the loosely associated subunit is Ssl2p (also called Rad25). In humans, the 5 subunit core is composed of XPD, p62, p55, p44, p34 and the loosely associated subunit is XPB." [GOC:krc, PMID:14500720, PMID:7813015] xref: GO:0000443 is_a: CCO:C0000089 ! SSL2-core TFIIH complex relationship: part_of CCO:C0000279 ! holo TFIIH complex [Term] id: CCO:C0000092 name: MIS12/MIND type complex namespace: cellular_component def: "A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1." [GOC:krc, PMID:14633972, PMID:16585270] synonym: "Mis12 complex" NARROW [] xref: GO:0000444 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0001912 ! PMF1_HUMAN relationship: location_of CCO:B0002122 ! MIS12_HUMAN relationship: location_of CCO:B0013263 ! NSL1_HUMAN-Phosphothreonine242 relationship: location_of CCO:B0064882 ! DSN1_HUMAN-Phosphoserine81 relationship: part_of CCO:C0000104 ! condensed chromosome kinetochore [Term] id: CCO:C0000093 name: THO complex part of transcription export complex namespace: cellular_component def: "The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits." [GO:krc, PMID:11060033, PMID:11979277, PMID:16983072] synonym: "THO complex part of TREX complex" EXACT [] xref: GO:0000445 is_a: CCO:C0000075 ! THO complex relationship: part_of CCO:C0000074 ! transcription export complex [Term] id: CCO:C0000094 name: nucleoplasmic THO complex namespace: cellular_component def: "The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits." [GO:krc, PMID:11060033, PMID:11979277, PMID:16983072] xref: GO:0000446 is_a: CCO:C0000075 ! THO complex is_a: CCO:C0000523 ! transcription elongation factor complex [Term] id: CCO:C0000095 name: RNA polymerase I upstream activating factor complex namespace: cellular_component def: "A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p." [PMID:11500378] synonym: "RNA polymerase I upstream activation factor complex" EXACT [] synonym: "UAF" EXACT [] xref: GO:0000500 is_a: CCO:C0000010 ! RNA polymerase I transcription factor complex [Term] id: CCO:C0000099 name: glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex namespace: cellular_component def: "An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast." [GOC:kp, GOC:rb, PMID:10944123, PMID:15163411] comment: Note that this term should not be confused with 'GPI-anchor transamidase complex ; GO:0042765', which represents a distinct complex with a different catalytic activity. synonym: "GPI-GlcNAc transferase complex" EXACT [] synonym: "GPI-GnT complex" EXACT [] synonym: "GPI-N-acetylglucosaminyltransferase complex" EXACT [] xref: GO:0000506 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001851 ! endoplasmic reticulum part [Term] id: CCO:C0000100 name: Rpd3L complex namespace: cellular_component def: "A multisubunit histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p." [GOC:rb, PMID:16286008, PMID:16314178] synonym: "Rpd3C(L)" EXACT [] xref: GO:0000508 is_a: CCO:C0000008 ! histone deacetylase complex [Term] id: CCO:C0000101 name: Rpd3S complex namespace: cellular_component def: "A multisubunit histone deacetylase complex that is involved in intragenic transcription repression through histone deacetylation. In S. cerevisiae, this complex consists of Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3." [GOC:rb, PMID:16286007, PMID:16286008] synonym: "Rpd3C(S)" EXACT [] xref: GO:0000509 is_a: CCO:C0000008 ! histone deacetylase complex [Term] id: CCO:C0000103 name: kinetochore namespace: cellular_component def: "A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules." [GOC:elh] subset: goslim_pir xref: GO:0000776 xref: GO:0005699 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001395 ! BUB1_HUMAN relationship: location_of CCO:B0001396 ! BUB3_HUMAN relationship: location_of CCO:B0001449 ! ZWINT_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001748 ! MD2L1_HUMAN relationship: location_of CCO:B0002019 ! PCAF_HUMAN relationship: location_of CCO:B0002252 ! SUGT1_HUMAN relationship: location_of CCO:B0005682 ! CENPH_HUMAN relationship: location_of CCO:B0010567 ! APC_HUMAN-Phosphoserine1038 relationship: location_of CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0011143 ! CENPC_HUMAN-Phosphoserine520 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014070 ! SMC1A_HUMAN-Phosphoserine951 relationship: location_of CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0032821 ! ZWILC_HUMAN relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0063000 ! SUMO3_HUMAN relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0067359 ! KIF22_HUMAN-Phosphoserine412 relationship: location_of CCO:B0068424 ! MYST1_HUMAN-Phosphoserine42 relationship: part_of CCO:C0002168 ! chromosome, centromeric region [Term] id: CCO:C0000104 name: condensed chromosome kinetochore namespace: cellular_component def: "A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules." [GOC:elh] xref: GO:0000777 is_a: CCO:C0000103 ! kinetochore relationship: location_of CCO:B0001395 ! BUB1_HUMAN relationship: location_of CCO:B0001440 ! DCTN3_HUMAN relationship: location_of CCO:B0001449 ! ZWINT_HUMAN relationship: location_of CCO:B0001912 ! PMF1_HUMAN relationship: location_of CCO:B0001963 ! KIF2B_HUMAN relationship: location_of CCO:B0001973 ! SPC24_HUMAN relationship: location_of CCO:B0002003 ! SKA2_HUMAN relationship: location_of CCO:B0002032 ! SKA1_HUMAN relationship: location_of CCO:B0002115 ! NUF2_HUMAN relationship: location_of CCO:B0002122 ! MIS12_HUMAN relationship: location_of CCO:B0002143 ! SPC25_HUMAN relationship: location_of CCO:B0011143 ! CENPC_HUMAN-Phosphoserine520 relationship: location_of CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0012613 ! KNTC1_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: location_of CCO:B0013263 ! NSL1_HUMAN-Phosphothreonine242 relationship: location_of CCO:B0014164 ! SPAG5_HUMAN-Phosphoserine249 relationship: location_of CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0031347 ! NDC80_HUMAN-Phosphoserine165 relationship: location_of CCO:B0032821 ! ZWILC_HUMAN relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0064292 ! CENPU_HUMAN-Phosphoserine111 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0064882 ! DSN1_HUMAN-Phosphoserine81 relationship: location_of CCO:B0068898 ! NU107_HUMAN-Phosphothreonine64 relationship: location_of CCO:B0068907 ! NU133_HUMAN-Phosphoserine501 relationship: part_of CCO:C0002169 ! condensed chromosome, centromeric region [Term] id: CCO:C0000105 name: condensed nuclear chromosome kinetochore namespace: cellular_component def: "A multisubunit complex that is located at the centromeric region of a condensed chromosome in the nucleus and provides an attachment point for the spindle microtubules." [GOC:elh] xref: GO:0000778 is_a: CCO:C0000104 ! condensed chromosome kinetochore is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0002170 ! condensed nuclear chromosome, centromeric region [Term] id: CCO:C0000108 name: chromosome, telomeric region namespace: cellular_component def: "The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins." [GOC:elh] comment: Note that this term can be used in place of the obsoleted cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. synonym: "telomere" RELATED [] xref: GO:0000781 is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0002021 ! RAD50_HUMAN relationship: location_of CCO:B0002033 ! PINX1_HUMAN relationship: location_of CCO:B0005503 ! POTE1_HUMAN relationship: location_of CCO:B0005504 ! ACD_HUMAN relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0014328 ! TE2IP_HUMAN-Phosphoserine154 relationship: location_of CCO:B0014336 ! TERF2_HUMAN-Phosphoserine380 relationship: location_of CCO:B0027184 ! Q6ZQQ5_HUMAN relationship: location_of CCO:B0038614 ! A6NJ87_HUMAN relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0056049 ! TEBP_HUMAN relationship: location_of CCO:B0057255 ! EST1A_HUMAN relationship: location_of CCO:B0070039 ! RIF1_HUMAN-Phosphoserine2176 relationship: location_of CCO:B0071340 ! TERF1_HUMAN-Phosphoserine435 relationship: location_of CCO:B0071342 ! TERT_HUMAN-Phosphothreonine1113 relationship: location_of CCO:B0071407 ! TINF2_HUMAN-Phosphoserine295 [Term] id: CCO:C0000109 name: telomere cap complex namespace: cellular_component def: "A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome." [GOC:elh] comment: Note that this term can be used in place of the obsoleted cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome. subset: goslim_pir subset: gosubset_prok xref: GO:0000782 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000108 ! chromosome, telomeric region [Term] id: CCO:C0000110 name: nuclear telomere cap complex namespace: cellular_component def: "A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome." [GOC:elh] comment: Note that this term can be used in place of the obsoleted cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome. xref: GO:0000783 is_a: CCO:C0000109 ! telomere cap complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0005504 ! ACD_HUMAN relationship: part_of CCO:C0000111 ! nuclear chromosome, telomeric region [Term] id: CCO:C0000111 name: nuclear chromosome, telomeric region namespace: cellular_component def: "The terminal region of a linear chromosome in the nucleus that includes the telomeric DNA repeats and associated proteins." [GOC:elh] comment: Note that this term can be used in place of the obsoleted cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. synonym: "nuclear chromosome, telomere" EXACT [] xref: GO:0000784 is_a: CCO:C0000108 ! chromosome, telomeric region is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0005503 ! POTE1_HUMAN relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0015646 ! ERCC1_HUMAN relationship: location_of CCO:B0069308 ! PIF1_HUMAN-Phosphoserine151 relationship: location_of CCO:B0069637 ! PURA_HUMAN-Phosphoserine8 [Term] id: CCO:C0000112 name: chromatin namespace: cellular_component def: "The ordered and organized complex of DNA and protein that forms the chromosome." [GOC:elh] synonym: "chromosome scaffold" RELATED [] xref: GO:0000785 xref: GO:0005717 is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0001391 ! SUV91_HUMAN relationship: location_of CCO:B0001589 ! MCM7_HUMAN relationship: location_of CCO:B0002184 ! HM20B_HUMAN relationship: location_of CCO:B0005417 ! SMRC2_HUMAN relationship: location_of CCO:B0005418 ! SMRC1_HUMAN relationship: location_of CCO:B0005693 ! ARI4A_HUMAN relationship: location_of CCO:B0005943 ! APTX_HUMAN relationship: location_of CCO:B0006082 ! CHD3_HUMAN relationship: location_of CCO:B0010965 ! CBX1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 relationship: location_of CCO:B0012198 ! HMGB1_HUMAN-Phosphoserine35 relationship: location_of CCO:B0012448 ! JUNB_HUMAN-Phosphoserine259 relationship: location_of CCO:B0012807 ! MCM2_HUMAN-Phosphoserine27 relationship: location_of CCO:B0012994 ! MPP8_HUMAN-Phosphoserine164 relationship: location_of CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013804 ! RB_HUMAN-Phosphothreonine826 relationship: location_of CCO:B0013820 ! RENT1_HUMAN-Phosphoserine1107 relationship: location_of CCO:B0014221 ! SSRP1_HUMAN-Phosphoserine444 relationship: location_of CCO:B0014378 ! TIP60_HUMAN-Phosphoserine86 relationship: location_of CCO:B0020267 ! SOX14_HUMAN relationship: location_of CCO:B0020283 ! SOX15_HUMAN relationship: location_of CCO:B0020286 ! O95130_HUMAN relationship: location_of CCO:B0021032 ! CHD2_HUMAN relationship: location_of CCO:B0033734 ! MAF_HUMAN relationship: location_of CCO:B0034640 ! CDYL1_HUMAN-Phosphoserine201 relationship: location_of CCO:B0034661 ! CHD1_HUMAN-Phosphoserine1356 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0036665 ! Q1M183_HUMAN relationship: location_of CCO:B0041249 ! HMGA2_HUMAN relationship: location_of CCO:B0050270 ! Q75MM1_HUMAN relationship: location_of CCO:B0050272 ! Q7Z684_HUMAN relationship: location_of CCO:B0050274 ! Q5T7C4_HUMAN relationship: location_of CCO:B0050275 ! HMG4L_HUMAN relationship: location_of CCO:B0050276 ! HMGLX_HUMAN relationship: location_of CCO:B0050277 ! HMGB4_HUMAN relationship: location_of CCO:B0050279 ! HMGB3_HUMAN relationship: location_of CCO:B0050283 ! Q16466_HUMAN relationship: location_of CCO:B0050286 ! HG3BL_HUMAN relationship: location_of CCO:B0050288 ! Q6NSH1_HUMAN relationship: location_of CCO:B0050289 ! Q5T7C6_HUMAN relationship: location_of CCO:B0050294 ! HMGB2_HUMAN relationship: location_of CCO:B0050299 ! Q5T7C0_HUMAN relationship: location_of CCO:B0053907 ! A6NMM4_HUMAN relationship: location_of CCO:B0053954 ! A8K1J1_HUMAN relationship: location_of CCO:B0054435 ! TOX3_HUMAN relationship: location_of CCO:B0054707 ! TOX_HUMAN relationship: location_of CCO:B0054805 ! CBX7_HUMAN relationship: location_of CCO:B0056013 ! CBX2_HUMAN relationship: location_of CCO:B0056191 ! Q1M182_HUMAN relationship: location_of CCO:B0056192 ! Q1M186_HUMAN relationship: location_of CCO:B0056820 ! Q6IPL9_HUMAN relationship: location_of CCO:B0057031 ! Q6ZP45_HUMAN relationship: location_of CCO:B0057928 ! CHD5_HUMAN relationship: location_of CCO:B0058932 ! ASF1B_HUMAN relationship: location_of CCO:B0059056 ! CHD7_HUMAN relationship: location_of CCO:B0059127 ! HM2L1_HUMAN relationship: location_of CCO:B0063028 ! OIP5_HUMAN relationship: location_of CCO:B0063391 ! UBE2B_HUMAN relationship: location_of CCO:B0063588 ! ARI4B_HUMAN-Phosphoserine1159 relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 relationship: location_of CCO:B0064102 ! CBX4_HUMAN-Phosphothreonine495 relationship: location_of CCO:B0064104 ! CBX6_HUMAN-Phosphoserine303 relationship: location_of CCO:B0064109 ! CBX8_HUMAN-Phosphoserine332 relationship: location_of CCO:B0064318 ! CHD4_HUMAN-Phosphothreonine1542 relationship: location_of CCO:B0064325 ! CHD6_HUMAN-Phosphoserine1069 relationship: location_of CCO:B0064338 ! CHD8_HUMAN-Phosphoserine1716 relationship: location_of CCO:B0064344 ! CHD9_HUMAN-Phosphoserine616 relationship: location_of CCO:B0066824 ! HMGA1_HUMAN-Phosphoserine36 relationship: location_of CCO:B0066832 ! HMGN2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0067230 ! JUND_HUMAN-Phosphoserine255 relationship: location_of CCO:B0067520 ! LAP2A_HUMAN-Phosphoserine66 relationship: location_of CCO:B0068295 ! MS3L1_HUMAN-Phosphoserine411 relationship: location_of CCO:B0068363 ! MYCN_HUMAN-Phosphothreonine58 relationship: location_of CCO:B0068424 ! MYST1_HUMAN-Phosphoserine42 relationship: location_of CCO:B0068858 ! NSBP1_HUMAN-Phosphoserine24 relationship: location_of CCO:B0068990 ! ORC2_HUMAN-Phosphoserine280 relationship: location_of CCO:B0070768 ! SP100_HUMAN-Phosphoserine459 relationship: location_of CCO:B0071003 ! SUV92_HUMAN-Phosphoserine381 relationship: location_of CCO:B0071456 ! TOX4_HUMAN-Phosphoserine182 [Term] id: CCO:C0000113 name: nucleosome namespace: cellular_component def: "A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures." [GOC:elh] subset: goslim_pir xref: GO:0000786 xref: GO:0005718 is_a: CCO:C0001494 ! protein-DNA complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0001481 ! HSP1_HUMAN relationship: location_of CCO:B0001482 ! PRM2_HUMAN relationship: location_of CCO:B0001526 ! H2AX_HUMAN relationship: location_of CCO:B0002149 ! PRM3_HUMAN relationship: location_of CCO:B0011999 ! H11_HUMAN-N-acetylserine2 relationship: location_of CCO:B0012002 ! H14_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0012013 ! H2B1C_HUMAN-N6-acetyllysine13 relationship: location_of CCO:B0012048 ! H31_HUMAN-N6-acetyllysine37 relationship: location_of CCO:B0012088 ! H32_HUMAN-N6-acetyllysine57 relationship: location_of CCO:B0012117 ! H33_HUMAN-N6-methyllysine28 relationship: location_of CCO:B0017927 ! MYST3_HUMAN relationship: location_of CCO:B0017931 ! MYST4_HUMAN relationship: location_of CCO:B0021914 ! H2A2A_HUMAN relationship: location_of CCO:B0039454 ! HILS1_HUMAN-Phosphothreonine130 relationship: location_of CCO:B0041139 ! H4_HUMAN-Phosphoserine2 relationship: location_of CCO:B0043831 ! H1FOO_HUMAN relationship: location_of CCO:B0054943 ! STP1_HUMAN relationship: location_of CCO:B0059032 ! H2AW_HUMAN relationship: location_of CCO:B0066678 ! H12_HUMAN-Phosphoserine173 relationship: location_of CCO:B0066679 ! H1X_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066682 ! H2A1C_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066694 ! H2AY_HUMAN-N6-methyllysine18 relationship: location_of CCO:B0066708 ! H2B1B_HUMAN-N6-acetyllysine109 relationship: location_of CCO:B0066710 ! H2B1H_HUMAN-N6-acetyllysine6 relationship: location_of CCO:B0066732 ! H31T_HUMAN-Citrulline18 relationship: part_of CCO:C0000112 ! chromatin [Term] id: CCO:C0000114 name: cytoplasmic nucleosome namespace: cellular_component def: "A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the cytoplasm into higher order structures." [GOC:elh] xref: GO:0000787 is_a: CCO:C0000113 ! nucleosome is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0000116 ! cytoplasmic chromatin [Term] id: CCO:C0000115 name: nuclear nucleosome namespace: cellular_component def: "A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures." [GOC:elh] xref: GO:0000788 is_a: CCO:C0000113 ! nucleosome is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000117 ! nuclear chromatin [Term] id: CCO:C0000116 name: cytoplasmic chromatin namespace: cellular_component def: "The ordered and organized complex of DNA and protein that forms the chromosome in the cytoplasm." [GOC:elh] xref: GO:0000789 is_a: CCO:C0000112 ! chromatin is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0001936 ! NPM2_HUMAN relationship: part_of CCO:C0000041 ! cytoplasmic chromosome [Term] id: CCO:C0000117 name: nuclear chromatin namespace: cellular_component def: "The ordered and organized complex of DNA and protein that forms the chromosome in the nucleus." [GOC:elh] xref: GO:0000790 is_a: CCO:C0000112 ! chromatin is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001400 ! O43832_HUMAN relationship: location_of CCO:B0001936 ! NPM2_HUMAN relationship: location_of CCO:B0002104 ! TIPIN_HUMAN relationship: location_of CCO:B0002235 ! TIM_HUMAN relationship: location_of CCO:B0013809 ! RCC1_HUMAN-Phosphothreonine411 relationship: location_of CCO:B0026255 ! KLDC3_HUMAN relationship: location_of CCO:B0043830 ! H1FNT_HUMAN [Term] id: CCO:C0000118 name: euchromatin namespace: cellular_component def: "A dispersed and relatively uncompacted form of chromatin." [GOC:elh] xref: GO:0000791 is_a: CCO:C0000112 ! chromatin relationship: location_of CCO:B0039404 ! DNM3A_HUMAN-Phosphoserine105 [Term] id: CCO:C0000119 name: heterochromatin namespace: cellular_component def: "A compact and highly condensed form of chromatin." [GOC:elh] xref: GO:0000792 is_a: CCO:C0000112 ! chromatin relationship: location_of CCO:B0012159 ! HDAC2_HUMAN-Phosphoserine394 relationship: location_of CCO:B0034711 ! DNMT1_HUMAN-Phosphoserine127 relationship: location_of CCO:B0048217 ! DAXX_HUMAN-Phosphoserine178 relationship: location_of CCO:B0070630 ! SMCA4_HUMAN-Phosphoserine613 [Term] id: CCO:C0000120 name: condensed chromosome namespace: cellular_component def: "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure." [GOC:elh] comment: Note that this term can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes an 'open mitosis' in which the nuclear envelope breaks down during mitosis. synonym: "cytoplasmic mitotic chromosome" RELATED [] synonym: "metaphase chromosome" RELATED [] synonym: "mitotic chromosome" RELATED [] xref: GO:0000793 is_a: CCO:C0000296 ! chromosome relationship: location_of CCO:B0001378 ! MSH4_HUMAN relationship: location_of CCO:B0001400 ! O43832_HUMAN relationship: location_of CCO:B0001450 ! SMC2_HUMAN relationship: location_of CCO:B0001562 ! RFA1_HUMAN relationship: location_of CCO:B0001721 ! RAD51_HUMAN relationship: location_of CCO:B0001923 ! Q6ZNA8_HUMAN relationship: location_of CCO:B0001957 ! SYCP3_HUMAN relationship: location_of CCO:B0010485 ! AKAP8_HUMAN-Phosphoserine339 relationship: location_of CCO:B0011292 ! CND1_HUMAN-Phosphoserine1376 relationship: location_of CCO:B0012198 ! HMGB1_HUMAN-Phosphoserine35 relationship: location_of CCO:B0050276 ! HMGLX_HUMAN relationship: location_of CCO:B0050294 ! HMGB2_HUMAN relationship: location_of CCO:B0063758 ! BAZ1B_HUMAN-Phosphoserine347 relationship: location_of CCO:B0064815 ! DNLI4_HUMAN-Phosphothreonine347 relationship: location_of CCO:B0069236 ! PESC_HUMAN-Phosphotyrosine548 relationship: location_of CCO:B0070643 ! SMCA5_HUMAN-Phosphoserine755 relationship: location_of CCO:B0071895 ! XRCC4_HUMAN-Phosphoserine327 [Term] id: CCO:C0000121 name: condensed nuclear chromosome namespace: cellular_component def: "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure that remains in the nucleus." [GOC:elh] comment: Note that this term and its children can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes a 'closed mitosis' in which the nuclear envelope does not break down during mitosis and for gene products that localize to a meiotic chromosome. synonym: "meiotic chromosome" RELATED [] synonym: "nuclear mitotic chromosome" RELATED [] xref: GO:0000794 is_a: CCO:C0000040 ! nuclear chromosome is_a: CCO:C0000120 ! condensed chromosome relationship: location_of CCO:B0001391 ! SUV91_HUMAN relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0001721 ! RAD51_HUMAN relationship: location_of CCO:B0001784 ! DMC1_HUMAN relationship: location_of CCO:B0001923 ! Q6ZNA8_HUMAN relationship: location_of CCO:B0002018 ! SC65_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0011213 ! CHK1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0013809 ! RCC1_HUMAN-Phosphothreonine411 relationship: location_of CCO:B0014070 ! SMC1A_HUMAN-Phosphoserine951 relationship: location_of CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0035550 ! RGS12_HUMAN-Phosphoserine874 relationship: location_of CCO:B0037714 ! DNM3L_HUMAN relationship: location_of CCO:B0039354 ! CDX2_HUMAN-Phosphoserine60 [Term] id: CCO:C0000122 name: synaptonemal complex namespace: cellular_component def: "A proteinaceous scaffold found between homologous chromosomes during meiosis." [GOC:elh] xref: GO:0000795 xref: GO:0005716 is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001378 ! MSH4_HUMAN relationship: location_of CCO:B0001696 ! UBC9_HUMAN relationship: location_of CCO:B0001900 ! Q5VXJ5_HUMAN relationship: location_of CCO:B0002018 ! SC65_HUMAN relationship: location_of CCO:B0002106 ! SYCP2_HUMAN relationship: location_of CCO:B0002209 ! STAG3_HUMAN relationship: location_of CCO:B0071024 ! SYCP1_HUMAN-Phosphotyrosine257 relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0000123 name: condensin complex namespace: cellular_component def: "A multisubunit protein complex that plays a central role in chromosome condensation." [GOC:elh] subset: goslim_pir synonym: "SMC complex" RELATED [] xref: GO:0000796 xref: GO:0005676 xref: GO:0008620 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0001450 ! SMC2_HUMAN relationship: location_of CCO:B0014085 ! SMC4_HUMAN-Phosphoserine1056 relationship: part_of CCO:C0000120 ! condensed chromosome [Term] id: CCO:C0000124 name: condensin core heterodimer namespace: cellular_component def: "The core heterodimer of a condensin complex, a multisubunit protein complex that plays a central role in chromosome condensation." [GOC:elh] synonym: "Smc2-Smc4 complex" NARROW [] xref: GO:0000797 xref: GO:0008621 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0011292 ! CND1_HUMAN-Phosphoserine1376 relationship: part_of CCO:C0000123 ! condensin complex [Term] id: CCO:C0000125 name: nuclear cohesin complex namespace: cellular_component def: "A protein complex required for cohesion between sister chromatids that remain in the nucleus." [GOC:elh] xref: GO:0000798 is_a: CCO:C0000538 ! cohesin complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0000126 name: nuclear condensin complex namespace: cellular_component def: "A multisubunit protein complex that plays a central role in the condensation of chromosomes that remain in the nucleus." [GOC:elh] xref: GO:0000799 is_a: CCO:C0000123 ! condensin complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001614 ! CNDD3_HUMAN relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0000127 name: lateral element namespace: cellular_component def: "A proteinaceous core found between sister chromatids during meiotic prophase." [GOC:elh] synonym: "axial element" RELATED [] xref: GO:0000800 is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001447 ! REC8_HUMAN relationship: location_of CCO:B0001957 ! SYCP3_HUMAN relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0014074 ! SMC1B_HUMAN-Phosphoserine882 relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: part_of CCO:C0000122 ! synaptonemal complex [Term] id: CCO:C0000128 name: central element namespace: cellular_component def: "A structural unit of the synaptonemal complex found between the lateral elements." [GOC:elh] xref: GO:0000801 is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001915 ! SYCE2_HUMAN relationship: location_of CCO:B0001960 ! SYCE1_HUMAN relationship: location_of CCO:B0071024 ! SYCP1_HUMAN-Phosphotyrosine257 relationship: part_of CCO:C0000122 ! synaptonemal complex [Term] id: CCO:C0000129 name: transverse filament namespace: cellular_component def: "A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them." [GOC:elh] xref: GO:0000802 is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001957 ! SYCP3_HUMAN relationship: location_of CCO:B0071024 ! SYCP1_HUMAN-Phosphotyrosine257 relationship: part_of CCO:C0000122 ! synaptonemal complex [Term] id: CCO:C0000130 name: sex chromosome namespace: cellular_component def: "A chromosome involved in sex determination." [GOC:elh] xref: GO:0000803 is_a: CCO:C0000296 ! chromosome [Term] id: CCO:C0000131 name: W chromosome namespace: cellular_component def: "The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females." [GOC:mah, ISBN:0321000382] xref: GO:0000804 is_a: CCO:C0000130 ! sex chromosome [Term] id: CCO:C0000132 name: X chromosome namespace: cellular_component def: "The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males." [GOC:mah, ISBN:0582227089] xref: GO:0000805 is_a: CCO:C0000130 ! sex chromosome [Term] id: CCO:C0000133 name: Y chromosome namespace: cellular_component def: "The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males." [GOC:mah, ISBN:0582227089] xref: GO:0000806 is_a: CCO:C0000130 ! sex chromosome [Term] id: CCO:C0000134 name: Z chromosome namespace: cellular_component def: "The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females." [GOC:mah, ISBN:0321000382] xref: GO:0000807 is_a: CCO:C0000130 ! sex chromosome [Term] id: CCO:C0000135 name: origin recognition complex namespace: cellular_component def: "A multisubunit complex that is located at the replication origins of a chromosome." [GOC:elh] subset: goslim_pir subset: gosubset_prok synonym: "ORC" EXACT [] synonym: "origin of replication recognition complex" EXACT [] xref: GO:0000808 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0068990 ! ORC2_HUMAN-Phosphoserine280 [Term] id: CCO:C0000136 name: cytoplasmic origin of replication recognition complex namespace: cellular_component def: "A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm." [GOC:elh] subset: gosubset_prok synonym: "cytoplasmic ORC" EXACT [] synonym: "prokaryotic ORC" RELATED [] xref: GO:0000809 is_a: CCO:C0000135 ! origin recognition complex is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0000041 ! cytoplasmic chromosome [Term] id: CCO:C0000137 name: GINS complex namespace: cellular_component def: "A multisubunit complex that associates with replication origins and is required for the initiation of DNA replication." [GOC:rn, PMID:12730134] synonym: "Go, Ichi, Ni and San complex" EXACT [] xref: GO:0000811 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001873 ! nuclear chromosome part [Term] id: CCO:C0000138 name: SWR1 complex namespace: cellular_component def: "A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits." [PMID:14645854, PMID:14690608] synonym: "SWR-C" EXACT [] xref: GO:0000812 is_a: CCO:C0000806 ! chromatin remodeling complex [Term] id: CCO:C0000139 name: ESCRT I complex namespace: cellular_component def: "An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes." [GOC:rb, PMID:12892785, PMID:12900393] synonym: "Endosomal Sorting Complex Required for Transport" BROAD [] xref: GO:0000813 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001859 ! endosomal part relationship: part_of CCO:C0000713 ! endosome membrane [Term] id: CCO:C0000140 name: ESCRT II complex namespace: cellular_component def: "An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes." [GOC:rb, PMID:12892785, PMID:12900393] synonym: "Endosomal Sorting Complex Required for Transport" BROAD [] xref: GO:0000814 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001859 ! endosomal part relationship: part_of CCO:C0000713 ! endosome membrane [Term] id: CCO:C0000141 name: ESCRT III complex namespace: cellular_component def: "An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes." [GOC:rb, PMID:12892785, PMID:12900393] synonym: "Endosomal Sorting Complex Required for Transport" BROAD [] xref: GO:0000815 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001859 ! endosomal part relationship: part_of CCO:C0000713 ! endosome membrane [Term] id: CCO:C0000142 name: COMA complex namespace: cellular_component def: "A multiprotein complex in yeast consisting of Ctf19p, Okp1p, Mcm1p, Ame1p. This complex bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly." [GOC:se, PMID:14633972] synonym: "Ctf19p-Okp1p-Mcm1p-Ame1p complex" EXACT [] xref: GO:0000817 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000105 ! condensed nuclear chromosome kinetochore [Term] id: CCO:C0000143 name: nuclear MIS12/MIND type complex namespace: cellular_component def: "A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1." [GOC:krc, GOC:se, PMID:14633972] synonym: "MIND complex" EXACT [] synonym: "Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex" EXACT [] xref: GO:0000818 is_a: CCO:C0000092 ! MIS12/MIND type complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000105 ! condensed nuclear chromosome kinetochore [Term] id: CCO:C0000144 name: spindle pole namespace: cellular_component def: "Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules." [GOC:clt] xref: GO:0000922 xref: GO:0030615 is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0001427 ! KTNA1_HUMAN relationship: location_of CCO:B0002100 ! KTNB1_HUMAN relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0011452 ! DCTN1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0012584 ! KIF11_HUMAN-Phosphothreonine926 relationship: location_of CCO:B0012613 ! KNTC1_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0012680 ! LATS1_HUMAN-Phosphoserine909 relationship: location_of CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: location_of CCO:B0014528 ! TPX2_HUMAN-Phosphoserine654 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0025212 ! SBDS_HUMAN relationship: location_of CCO:B0067579 ! LATS2_HUMAN-Phosphoserine380 relationship: part_of CCO:C0000388 ! spindle [Term] id: CCO:C0000145 name: equatorial microtubule organizing center namespace: cellular_component def: "A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis." [PMID:11792817] synonym: "EMTOC" EXACT [] synonym: "equatorial microtubule organising centre" EXACT [] xref: GO:0000923 is_a: CCO:C0000385 ! microtubule organizing center is_a: CCO:C0001404 ! cell division site part [Term] id: CCO:C0000146 name: gamma-tubulin ring complex, centrosomal namespace: cellular_component def: "A centrosome-localized multiprotein complex composed of gamma-tubulin and other non-tubulin proteins assembled into a ring structure that is thought to be the unit of nucleation at the minus end of a microtubule. Gamma-tubulin small complexes are thought to be the core repeating units of the ring." [GOC:clt, GOC:mtg_sensu, PMID:12134075, PMID:17021256] synonym: "gamma-tubulin large complex (sensu Metazoa)" EXACT [] synonym: "gamma-tubulin large complex, centrosomal" EXACT [] synonym: "gamma-tubulin ring complex, centrosomal (sensu Metazoa)" EXACT [] xref: GO:0000924 xref: GO:0000925 xref: GO:0000926 is_a: CCO:C0000536 ! gamma-tubulin ring complex relationship: part_of CCO:C0000043 ! pericentriolar material [Term] id: CCO:C0000147 name: gamma-tubulin small complex, centrosomal namespace: cellular_component def: "A centrosomal complex usually comprising two gamma-tubulin molecules, at least two conserved non-tubulin proteins that multimerize along with additional non-tubulin proteins in animal cells into larger functional complexes. Gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex." [GOC:mtg_sensu, PMID:12134075] synonym: "gamma-tubulin small complex (sensu Metazoa)" EXACT [] xref: GO:0000927 is_a: CCO:C0000537 ! gamma-tubulin small complex is_a: CCO:C0001849 ! cytoskeletal part [Term] id: CCO:C0000148 name: gamma-tubulin small complex, spindle pole body namespace: cellular_component def: "A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms." [GOC:mtg_sensu, PMID:12134075] synonym: "gamma-tubulin complex (sensu Saccharomyces)" BROAD [] synonym: "Tub4 complex" EXACT [] xref: GO:0000928 is_a: CCO:C0000537 ! gamma-tubulin small complex is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0000386 ! spindle pole body [Term] id: CCO:C0000149 name: gamma-tubulin complex namespace: cellular_component def: "A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species." [GOC:clt, PMID:12134075] subset: goslim_pir xref: GO:0000930 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001869 ! microtubule organizing center part relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0011243 ! CKAP5_HUMAN-Phosphoserine816 relationship: location_of CCO:B0063112 ! UXT_HUMAN [Term] id: CCO:C0000150 name: gamma-tubulin large complex namespace: cellular_component def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes." [GOC:mtg_sensu, PMID:12134075] synonym: "gamma-tubulin large complex (sensu Schizosaccharomyces)" EXACT [] xref: GO:0000929 xref: GO:0000931 is_a: CCO:C0000149 ! gamma-tubulin complex is_a: CCO:C0001849 ! cytoskeletal part [Term] id: CCO:C0000151 name: cytoplasmic mRNA processing body namespace: cellular_component def: "A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci." [GOC:clt, PMID:12730603] synonym: "cytoplasmic foci" RELATED [] synonym: "P body" EXACT [] synonym: "P-body" EXACT [] xref: GO:0000932 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000152 name: adventitious septum namespace: cellular_component def: "A cell septum whose formation is independent of nuclear division." [GOC:clt, ISBN:0471940526] xref: GO:0000933 is_a: CCO:C0001008 ! cell septum [Term] id: CCO:C0000153 name: porous cell septum namespace: cellular_component def: "A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments." [GOC:clt] synonym: "porous septum" BROAD [] xref: GO:0000934 is_a: CCO:C0001008 ! cell septum [Term] id: CCO:C0000154 name: barrier septum namespace: cellular_component def: "A septum which spans a cell and does not allow exchange of organelles or cytoplasm between compartments." [GOC:clt] synonym: "complete septum" EXACT [] xref: GO:0000935 is_a: CCO:C0001008 ! cell septum [Term] id: CCO:C0000155 name: primary cell septum namespace: cellular_component def: "A cell septum that forms following nuclear division." [GOC:clt, ISBN:0471940526] synonym: "primary septum" BROAD [] xref: GO:0000936 is_a: CCO:C0001008 ! cell septum [Term] id: CCO:C0000156 name: dolipore septum namespace: cellular_component def: "A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome)." [GOC:clt] xref: GO:0000937 is_a: CCO:C0000153 ! porous cell septum [Term] id: CCO:C0000157 name: GARP complex namespace: cellular_component def: "A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles." [GOC:clt, GOC:rn, PMID:10637310, PMID:12077354, PMID:12446664] synonym: "Golgi associated retrograde protein complex" EXACT [] synonym: "VFT tethering complex" EXACT [] synonym: "Vps fifty three tethering complex" EXACT [] xref: GO:0000938 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001850 ! Golgi apparatus part is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0000158 name: inner kinetochore of condensed chromosome namespace: cellular_component def: "The region of a condensed chromosome kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome." [GOC:clt, PMID:10619130, PMID:11483983] synonym: "inner centromere core complex" RELATED [] synonym: "inner kinetochore plate" NARROW [] xref: GO:0000939 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0068990 ! ORC2_HUMAN-Phosphoserine280 relationship: part_of CCO:C0000104 ! condensed chromosome kinetochore [Term] id: CCO:C0000159 name: outer kinetochore of condensed chromosome namespace: cellular_component def: "The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions." [GOC:clt, PMID:11483983] synonym: "outer kinetochore plate" NARROW [] xref: GO:0000940 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: part_of CCO:C0000104 ! condensed chromosome kinetochore [Term] id: CCO:C0000160 name: inner kinetochore of condensed nuclear chromosome namespace: cellular_component def: "The region of a condensed nuclear chromosome kinetochore closest to centromeric DNA; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome." [GOC:clt, PMID:10619130, PMID:1148398] xref: GO:0000941 is_a: CCO:C0000158 ! inner kinetochore of condensed chromosome is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000105 ! condensed nuclear chromosome kinetochore [Term] id: CCO:C0000161 name: outer kinetochore of condensed nuclear chromosome namespace: cellular_component def: "The region of a condensed nuclear chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions." [GOC:clt, PMID:1148398] xref: GO:0000942 is_a: CCO:C0000159 ! outer kinetochore of condensed chromosome is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000105 ! condensed nuclear chromosome kinetochore [Term] id: CCO:C0000162 name: retrotransposon nucleocapsid namespace: cellular_component def: "A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog." [GOC:clt, PMID:10861903] synonym: "Virus-like particle" EXACT [] synonym: "VLP" EXACT [] xref: GO:0000943 is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000163 name: mating projection base namespace: cellular_component def: "The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone." [GOC:mcc] synonym: "base of shmoo tip" NARROW [] synonym: "conjugation tube base" NARROW [] xref: GO:0001400 is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0000488 ! mating projection [Term] id: CCO:C0000164 name: mitochondrial sorting and assembly machinery complex namespace: cellular_component def: "A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex." [PMID:12891361] comment: See also the cellular component term 'mitochondrial outer membrane translocase complex ; GO:0005742'. synonym: "SAM complex" EXACT [] synonym: "TOB complex" EXACT [] xref: GO:0001401 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000327 ! mitochondrial outer membrane [Term] id: CCO:C0000165 name: presequence translocase-associated import motor namespace: cellular_component def: "Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the presequence translocase complex; hydrolyzes ATP to provide the force to drive import of proteins into the mitochondrial matrix." [GOC:mcc, PMID:14517234, PMID:14638855] synonym: "mitochondrial import motor" EXACT [] synonym: "PAM complex" EXACT [] synonym: "pre-sequence translocase-associated import motor" EXACT [] xref: GO:0001405 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000330 ! mitochondrial inner membrane presequence translocase complex [Term] id: CCO:C0000166 name: hyphal tip namespace: cellular_component def: "The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation." [GOC:mcc] subset: goslim_candida xref: GO:0001411 is_a: CCO:C0001007 ! site of polarized growth [Term] id: CCO:C0000167 name: voltage-gated sodium channel complex namespace: cellular_component def: "A sodium channel in a cell membrane whose opening is governed by the membrane potential." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "voltage gated sodium channel complex" EXACT [] synonym: "voltage-dependent sodium channel complex" EXACT [] synonym: "voltage-sensitive sodium channel complex" EXACT [] xref: GO:0001518 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0006346 ! SCN5A_HUMAN relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000168 name: outer dense fiber namespace: cellular_component def: "Structure or material found in the flagella of mammalian sperm that surrounds each of the nine microtubule doublets, giving a 9 + 9 + 2 arrangement rather than the 9 + 2 pattern usually seen. These dense fibers are stiff and noncontractile." [ISBN:0824072820] synonym: "outer dense fibre" EXACT [] xref: GO:0001520 is_a: CCO:C0001866 ! axoneme part [Term] id: CCO:C0000169 name: microfibril namespace: cellular_component def: "Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins." [http://www.xrefer.com/entry/490235] synonym: "extended fibrils" EXACT [] synonym: "fibrillin" RELATED [] xref: GO:0001527 is_a: CCO:C0001734 ! fibril relationship: location_of CCO:B0020123 ! MFAP4_HUMAN [Term] id: CCO:C0000170 name: cornified envelope namespace: cellular_component def: "An insoluble protein structure formed under the plasma membrane of cornifying epithelial cells." [PMID:11112355] xref: GO:0001533 is_a: CCO:C0000421 ! cytoskeleton relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0006322 ! CYTA_HUMAN relationship: location_of CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:C0000171 name: radial spoke namespace: cellular_component def: "Protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules." [ISBN:0124325653, PMID:9450971] subset: goslim_pir xref: GO:0001534 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part [Term] id: CCO:C0000172 name: radial spokehead namespace: cellular_component def: "Protein complex forming part of eukaryotic flagellar apparatus." [GOC:hjd] xref: GO:0001535 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part relationship: part_of CCO:C0000171 ! radial spoke [Term] id: CCO:C0000173 name: radial spoke stalk namespace: cellular_component def: "Globular portion of the radial spoke that projects towards the central pair of microtubules." [GOC:hjd] xref: GO:0001536 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part relationship: part_of CCO:C0000171 ! radial spoke [Term] id: CCO:C0000174 name: fibrillar center namespace: cellular_component def: "A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures." [PMID:10754561] synonym: "fibrillar centre" EXACT [] xref: GO:0001650 is_a: CCO:C0001871 ! nucleolar part relationship: location_of CCO:B0026279 ! IF3EI_HUMAN [Term] id: CCO:C0000175 name: dense fibrillar component namespace: cellular_component def: "A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins." [PMID:10754561] xref: GO:0001651 is_a: CCO:C0001871 ! nucleolar part [Term] id: CCO:C0000176 name: granular component namespace: cellular_component def: "A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm." [PMID:10754561] xref: GO:0001652 is_a: CCO:C0001871 ! nucleolar part [Term] id: CCO:C0000177 name: acrosome namespace: cellular_component def: "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." [ISBN:0124325653, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0001669 is_a: CCO:C0000347 ! lysosome relationship: location_of CCO:B0006064 ! CASC5_HUMAN relationship: location_of CCO:B0054915 ! HEXB_HUMAN relationship: location_of CCO:B0063026 ! NCF2_HUMAN relationship: location_of CCO:B0063303 ! VPP2_HUMAN relationship: location_of CCO:B0065533 ! AKAP3_HUMAN-Phosphoserine612 relationship: location_of CCO:B0069906 ! RGAP1_HUMAN-Phosphoserine600 [Term] id: CCO:C0000178 name: male germ cell nucleus namespace: cellular_component def: "The nucleus of a male germ cell, a cell specialized to produce haploid gametes, and its descendents." [GOC:hjd, GOC:mtg_sensu, http://cancerweb.ncl.ac.uk] synonym: "male germ cell nucleus (sensu Metazoa)" EXACT [] synonym: "male germ-cell nucleus" EXACT [] synonym: "male germ-cell nucleus (sensu Metazoa)" EXACT [] xref: GO:0001673 xref: GO:0043081 is_a: CCO:C0001713 ! germ cell nucleus relationship: location_of CCO:B0039454 ! HILS1_HUMAN-Phosphothreonine130 [Term] id: CCO:C0000179 name: female germ cell nucleus namespace: cellular_component def: "The nucleus of the female germ cell, a cell specialized to produce haploid gametes, and its descendents." [GOC:hjd, http://cancerweb.ncl.ac.uk] synonym: "female germ cell nucleus (sensu Metazoa)" EXACT [] synonym: "female germ-cell nucleus" EXACT [] synonym: "female germ-cell nucleus (sensu Animalia)" EXACT [] xref: GO:0001674 xref: GO:0043080 is_a: CCO:C0001713 ! germ cell nucleus relationship: location_of CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:C0000180 name: stress fiber namespace: cellular_component def: "Bundle of microfilaments and other proteins found in fibroblasts." [ISBN:0124325653] synonym: "stress fibre" EXACT [] xref: GO:0001725 is_a: CCO:C0001449 ! actin filament bundle relationship: location_of CCO:B0001397 ! ACTN4_HUMAN relationship: location_of CCO:B0013990 ! SEP11_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0014006 ! SEPT7_HUMAN-Phosphoserine423 relationship: location_of CCO:B0014015 ! SEPT9_HUMAN-Phosphoserine89 relationship: location_of CCO:B0032855 ! MYH10_HUMAN-Phosphothreonine1960 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0066163 ! FERM2_HUMAN-Phosphoserine181 relationship: location_of CCO:B0067657 ! LIMA1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0070469 ! SH2B2_HUMAN-Phosphotyrosine629 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000181 name: ruffle namespace: cellular_component def: "Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork." [ISBN:0124325653] synonym: "membrane ruffle" RELATED [] xref: GO:0001726 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0001494 ! S10A6_HUMAN relationship: location_of CCO:B0001546 ! NDKB_HUMAN relationship: location_of CCO:B0001708 ! CDK6_HUMAN relationship: location_of CCO:B0010760 ! BCAR1_HUMAN-Phosphotyrosine362 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013948 ! S100B_HUMAN-Blocked amino end (Ser)2 relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0026217 ! ITA5_HUMAN relationship: location_of CCO:B0031341 ! MTSS1_HUMAN-Phosphotyrosine526 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0054370 ! ITBP1_HUMAN relationship: location_of CCO:B0055508 ! ARFP2_HUMAN relationship: location_of CCO:B0055616 ! ARF6_HUMAN relationship: location_of CCO:B0056892 ! Q6P5Z4_HUMAN relationship: location_of CCO:B0056928 ! Q6QEF7_HUMAN relationship: location_of CCO:B0057029 ! FGD5_HUMAN relationship: location_of CCO:B0057198 ! FGD2_HUMAN relationship: location_of CCO:B0057306 ! PDPN_HUMAN relationship: location_of CCO:B0058282 ! FGD4_HUMAN relationship: location_of CCO:B0058838 ! TNR12_HUMAN relationship: location_of CCO:B0062775 ! TESC_HUMAN relationship: location_of CCO:B0063370 ! SRC8_HUMAN relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: location_of CCO:B0066179 ! FGD3_HUMAN-Phosphoserine128 relationship: location_of CCO:B0066183 ! FGD6_HUMAN-Phosphoserine721 relationship: location_of CCO:B0069419 ! PLSL_HUMAN-Phosphotyrosine28 relationship: location_of CCO:B0069929 ! RHG01_HUMAN-Phosphotyrosine65 relationship: location_of CCO:B0070274 ! S10AB_HUMAN-Phosphothreonine10 relationship: location_of CCO:B0070469 ! SH2B2_HUMAN-Phosphotyrosine629 relationship: part_of CCO:C0001172 ! leading edge [Term] id: CCO:C0000182 name: sex chromatin namespace: cellular_component def: "A condensed mass of compacted chromatin that represents an inactivated X chromosome." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0001739 is_a: CCO:C0000310 ! nuclear heterochromatin relationship: location_of CCO:B0020553 ! RING1_HUMAN relationship: location_of CCO:B0056036 ! SUZ12_HUMAN relationship: part_of CCO:C0000130 ! sex chromosome [Term] id: CCO:C0000183 name: Barr body namespace: cellular_component def: "A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery." [GOC:hjd] xref: GO:0001740 is_a: CCO:C0000132 ! X chromosome is_a: CCO:C0000182 ! sex chromatin relationship: location_of CCO:B0012117 ! H33_HUMAN-N6-methyllysine28 relationship: location_of CCO:B0059032 ! H2AW_HUMAN relationship: location_of CCO:B0066694 ! H2AY_HUMAN-N6-methyllysine18 [Term] id: CCO:C0000184 name: XY body namespace: cellular_component def: "A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery." [GOC:hjd] xref: GO:0001741 is_a: CCO:C0000182 ! sex chromatin [Term] id: CCO:C0000185 name: photoreceptor outer segment namespace: cellular_component def: "The outer segment of a vertebrate photoreceptor that contains discs of photoreceptive membranes." [ISBN:0824072820] xref: GO:0001750 is_a: CCO:C0001281 ! nonmotile primary cilium relationship: location_of CCO:B0002265 ! USH1C_HUMAN relationship: location_of CCO:B0054879 ! OPSB_HUMAN relationship: location_of CCO:B0058877 ! CNGB3_HUMAN relationship: location_of CCO:B0068975 ! OPSD_HUMAN-Phosphoserine343 [Term] id: CCO:C0000186 name: immunological synapse namespace: cellular_component def: "An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction." [GOC:mgi_curators, PMID:11244041, PMID:11376300] synonym: "c-SMAC" NARROW [PMID:14724296] synonym: "supramolecular activation cluster" EXACT [PMID:14724296] xref: GO:0001772 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0054971 ! GRAB_HUMAN relationship: location_of CCO:B0055002 ! GRAA_HUMAN relationship: location_of CCO:B0067581 ! LAT_HUMAN-Phosphoserine84 [Term] id: CCO:C0000187 name: phagocytic cup namespace: cellular_component def: "An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome." [PMID:10358769] xref: GO:0001891 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0069419 ! PLSL_HUMAN-Phosphotyrosine28 [Term] id: CCO:C0000188 name: photoreceptor inner segment namespace: cellular_component def: "The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs." [GOC:add, PMID:12019563] subset: goslim_pir xref: GO:0001917 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0002265 ! USH1C_HUMAN [Term] id: CCO:C0000189 name: uropod namespace: cellular_component def: "A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:12714569, PMID:12787750] synonym: "distal pole complex" RELATED [] synonym: "retractile pole" RELATED [] synonym: "uropodium" EXACT [] xref: GO:0001931 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0055047 ! LEUK_HUMAN relationship: part_of CCO:C0001174 ! trailing edge [Term] id: CCO:C0000190 name: female pronucleus namespace: cellular_component def: "The pronucleus originating from the ovum that is being fertilized." [GOC:hjd, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0001939 is_a: CCO:C0001889 ! pronucleus relationship: location_of CCO:B0001538 ! CCNA2_HUMAN relationship: location_of CCO:B0010485 ! AKAP8_HUMAN-Phosphoserine339 relationship: location_of CCO:B0070039 ! RIF1_HUMAN-Phosphoserine2176 [Term] id: CCO:C0000191 name: male pronucleus namespace: cellular_component def: "The pronucleus originating from the spermatozoa that was involved in fertilization." [GOC:hjd, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0001940 is_a: CCO:C0001889 ! pronucleus relationship: location_of CCO:B0001538 ! CCNA2_HUMAN relationship: location_of CCO:B0070039 ! RIF1_HUMAN-Phosphoserine2176 [Term] id: CCO:C0000192 name: PME fraction namespace: cellular_component def: "The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes." [GOC:mgi_curators, PMID:11562363, PMID:15601832] xref: GO:0001950 is_a: CCO:C0000046 ! cell fraction relationship: part_of CCO:C0000244 ! membrane fraction [Term] id: CCO:C0000193 name: inner acrosomal membrane namespace: cellular_component def: "The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane." [GOC:dph, PMID:3899643, PMID:8936405] xref: GO:0002079 is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0000194 ! acrosomal membrane [Term] id: CCO:C0000194 name: acrosomal membrane namespace: cellular_component def: "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." [GOC:dph] xref: GO:0002080 is_a: CCO:C0001127 ! organelle membrane relationship: location_of CCO:B0057369 ! SACA3_HUMAN relationship: part_of CCO:C0000177 ! acrosome [Term] id: CCO:C0000195 name: outer acrosomal membrane namespace: cellular_component def: "The acrosomal region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction." [GOC:dph, PMID:8936405] xref: GO:0002081 is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0000194 ! acrosomal membrane [Term] id: CCO:C0000196 name: caveolar macromolecular signaling complex namespace: cellular_component def: "A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3)." [PMID:16648270] synonym: "caveolar macromolecular signalling complex" EXACT [] xref: GO:0002095 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000458 ! caveola [Term] id: CCO:C0000197 name: polkadots namespace: cellular_component def: "A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals." [PMID:14724296, PMID:16495340] comment: Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots. xref: GO:0002096 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000198 name: podosome namespace: cellular_component def: "An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm." [PMID:12837608, PMID:15890982] comment: Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation. xref: GO:0002102 is_a: CCO:C0001742 ! organelle is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0000199 name: BRCA2-BRAF35 complex namespace: cellular_component def: "A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis." [GOC:hjd, PMID:11207365] xref: GO:0002111 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000200 name: cellular_component namespace: cellular_component def: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. Note that when this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this. subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "cellular component unknown" NARROW [] xref: GO:0005575 xref: GO:0008372 is_a: CCO:U0000001 ! biological continuant relationship: location_of CCO:B0001519 ! CCNB1_HUMAN relationship: location_of CCO:B0001561 ! G0S2_HUMAN relationship: location_of CCO:B0001666 ! HRSL3_HUMAN relationship: location_of CCO:B0001763 ! CUL4B_HUMAN relationship: location_of CCO:B0001786 ! Q14569_HUMAN relationship: location_of CCO:B0001815 ! Q16164_HUMAN relationship: location_of CCO:B0001975 ! PAPD5_HUMAN relationship: location_of CCO:B0001989 ! UBA3_HUMAN relationship: location_of CCO:B0002033 ! PINX1_HUMAN relationship: location_of CCO:B0002035 ! CHFR_HUMAN relationship: location_of CCO:B0002044 ! CK5P3_HUMAN relationship: location_of CCO:B0002062 ! CK5P1_HUMAN relationship: location_of CCO:B0002068 ! Q99539_HUMAN relationship: location_of CCO:B0002069 ! Q99540_HUMAN relationship: location_of CCO:B0002090 ! SPI2A_HUMAN relationship: location_of CCO:B0002121 ! Q9GZT1_HUMAN relationship: location_of CCO:B0002147 ! BRMS1_HUMAN relationship: location_of CCO:B0002149 ! PRM3_HUMAN relationship: location_of CCO:B0002164 ! GKN1_HUMAN relationship: location_of CCO:B0002174 ! BTG4_HUMAN relationship: location_of CCO:B0002198 ! SEPT3_HUMAN relationship: location_of CCO:B0002238 ! MARE3_HUMAN relationship: location_of CCO:B0002246 ! OSGI2_HUMAN relationship: location_of CCO:B0002263 ! EID1_HUMAN relationship: location_of CCO:B0005174 ! NADC_HUMAN relationship: location_of CCO:B0005183 ! PLDN_HUMAN relationship: location_of CCO:B0005266 ! MAGAC_HUMAN relationship: location_of CCO:B0005401 ! KBTB7_HUMAN relationship: location_of CCO:B0005550 ! RGL1_HUMAN relationship: location_of CCO:B0005556 ! EXOS8_HUMAN relationship: location_of CCO:B0005568 ! TR112_HUMAN relationship: location_of CCO:B0005591 ! DISC1_HUMAN relationship: location_of CCO:B0005666 ! SOS2_HUMAN relationship: location_of CCO:B0005892 ! MK11_HUMAN relationship: location_of CCO:B0005912 ! GNDS_HUMAN relationship: location_of CCO:B0005936 ! FANCF_HUMAN relationship: location_of CCO:B0005956 ! MEGF6_HUMAN relationship: location_of CCO:B0005957 ! MEGF8_HUMAN relationship: location_of CCO:B0006174 ! CG020_HUMAN relationship: location_of CCO:B0006216 ! PKHA4_HUMAN relationship: location_of CCO:B0006351 ! WBP2_HUMAN relationship: location_of CCO:B0010585 ! ARAF_HUMAN-Phosphoserine257 relationship: location_of CCO:B0011226 ! CJ119_HUMAN-Phosphothreonine160 relationship: location_of CCO:B0011819 ! FACD2_HUMAN-Phosphoserine717 relationship: location_of CCO:B0012184 ! HGF_HUMAN-Pyrrolidone carboxylic acid32 relationship: location_of CCO:B0012480 ! K2C6A_HUMAN-Phosphoserine60 relationship: location_of CCO:B0012943 ! MK03_HUMAN-Phosphotyrosine204 relationship: location_of CCO:B0012984 ! MPIP1_HUMAN-Phosphoserine124 relationship: location_of CCO:B0013035 ! MTMR6_HUMAN-Phosphoserine561 relationship: location_of CCO:B0013567 ! PLCG1_HUMAN-Phosphotyrosine1253 relationship: location_of CCO:B0013955 ! SACS_HUMAN-Phosphothreonine4263 relationship: location_of CCO:B0014000 ! SEPT6_HUMAN-Phosphoserine411 relationship: location_of CCO:B0014047 ! SGTA_HUMAN-Phosphothreonine303 relationship: location_of CCO:B0014052 ! SH3B4_HUMAN-Phosphoserine637 relationship: location_of CCO:B0014449 ! TOPK_HUMAN-Phosphothreonine200 relationship: location_of CCO:B0015073 ! RBMS1_HUMAN relationship: location_of CCO:B0016049 ! I2C2_HUMAN relationship: location_of CCO:B0016326 ! AAKG2_HUMAN relationship: location_of CCO:B0018485 ! CLTR2_HUMAN relationship: location_of CCO:B0018759 ! M3KL4_HUMAN relationship: location_of CCO:B0019143 ! ASGR2_HUMAN relationship: location_of CCO:B0019657 ! ATL4_HUMAN relationship: location_of CCO:B0020052 ! CHIC2_HUMAN relationship: location_of CCO:B0021156 ! SCND2_HUMAN relationship: location_of CCO:B0021160 ! Q07644_HUMAN relationship: location_of CCO:B0021303 ! ZFAN6_HUMAN relationship: location_of CCO:B0022431 ! OSGI1_HUMAN relationship: location_of CCO:B0022862 ! Q9UDD8_HUMAN relationship: location_of CCO:B0023306 ! DLG3_HUMAN relationship: location_of CCO:B0024842 ! RARB_HUMAN relationship: location_of CCO:B0025452 ! Q15157_HUMAN relationship: location_of CCO:B0025459 ! PM2L2_HUMAN relationship: location_of CCO:B0025462 ! Q16603_HUMAN relationship: location_of CCO:B0025463 ! PM2L1_HUMAN relationship: location_of CCO:B0025464 ! PM2L8_HUMAN relationship: location_of CCO:B0027730 ! SIN1_HUMAN relationship: location_of CCO:B0029122 ! BOK_HUMAN relationship: location_of CCO:B0032550 ! RAB8B_HUMAN relationship: location_of CCO:B0032571 ! HOP2_HUMAN relationship: location_of CCO:B0035141 ! LRRF2_HUMAN-Phosphoserine333 relationship: location_of CCO:B0035649 ! SGK2_HUMAN-Phosphoserine416 relationship: location_of CCO:B0037017 ! ARHG4_HUMAN relationship: location_of CCO:B0039467 ! IF5A2_HUMAN-Hypusine50 relationship: location_of CCO:B0039498 ! M3K9_HUMAN-Phosphoserine934 relationship: location_of CCO:B0039811 ! BIRC6_HUMAN relationship: location_of CCO:B0040474 ! ICBR_HUMAN relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0041218 ! TNIK_HUMAN-Phosphothreonine581 relationship: location_of CCO:B0041526 ! ANK3_HUMAN relationship: location_of CCO:B0042028 ! ENOPH_HUMAN relationship: location_of CCO:B0043321 ! M4K4_HUMAN-Phosphoserine639 relationship: location_of CCO:B0043495 ! TRI39_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0043552 ! PI51A_HUMAN relationship: location_of CCO:B0043707 ! SPSB2_HUMAN relationship: location_of CCO:B0043862 ! CC85B_HUMAN relationship: location_of CCO:B0048182 ! CCND1_HUMAN-Phosphotyrosine226 relationship: location_of CCO:B0048264 ! FMN2_HUMAN-Phosphoserine400 relationship: location_of CCO:B0048312 ! M3K1_HUMAN-Phosphoserine292 relationship: location_of CCO:B0050221 ! ZN75A_HUMAN relationship: location_of CCO:B0050818 ! WIT1_HUMAN relationship: location_of CCO:B0052294 ! ARS2_HUMAN-Phosphoserine540 relationship: location_of CCO:B0052370 ! EHMT2_HUMAN-Phosphoserine569 relationship: location_of CCO:B0054294 ! O00172_HUMAN relationship: location_of CCO:B0054326 ! O00485_HUMAN relationship: location_of CCO:B0054327 ! O00486_HUMAN relationship: location_of CCO:B0054339 ! TRI38_HUMAN relationship: location_of CCO:B0054347 ! SOCS7_HUMAN relationship: location_of CCO:B0054396 ! IPP4_HUMAN relationship: location_of CCO:B0054434 ! O15376_HUMAN relationship: location_of CCO:B0054452 ! SI1L1_HUMAN relationship: location_of CCO:B0054465 ! PROD_HUMAN relationship: location_of CCO:B0054487 ! O43535_HUMAN relationship: location_of CCO:B0054496 ! O43594_HUMAN relationship: location_of CCO:B0054513 ! GATCL_HUMAN relationship: location_of CCO:B0054515 ! CIKS_HUMAN relationship: location_of CCO:B0054519 ! TLX2_HUMAN relationship: location_of CCO:B0054527 ! O43851_HUMAN relationship: location_of CCO:B0054571 ! PDE8A_HUMAN relationship: location_of CCO:B0054621 ! O75353_HUMAN relationship: location_of CCO:B0054632 ! NDK6_HUMAN relationship: location_of CCO:B0054641 ! FRAT2_HUMAN relationship: location_of CCO:B0054722 ! HRBL_HUMAN relationship: location_of CCO:B0054742 ! PDE8B_HUMAN relationship: location_of CCO:B0054756 ! GDF11_HUMAN relationship: location_of CCO:B0054786 ! O95724_HUMAN relationship: location_of CCO:B0054787 ! O95725_HUMAN relationship: location_of CCO:B0054789 ! O95745_HUMAN relationship: location_of CCO:B0054795 ! CER1_HUMAN relationship: location_of CCO:B0054973 ! POK10_HUMAN relationship: location_of CCO:B0054997 ! DCOR_HUMAN relationship: location_of CCO:B0055168 ! PRTN3_HUMAN relationship: location_of CCO:B0055323 ! GDNF_HUMAN relationship: location_of CCO:B0055352 ! CASP2_HUMAN relationship: location_of CCO:B0055433 ! RGS6_HUMAN relationship: location_of CCO:B0055515 ! PDE1A_HUMAN relationship: location_of CCO:B0055661 ! OX26_HUMAN relationship: location_of CCO:B0055667 ! SHC2_HUMAN relationship: location_of CCO:B0055689 ! TSPY1_HUMAN relationship: location_of CCO:B0055691 ! ILRL1_HUMAN relationship: location_of CCO:B0055770 ! TNFC_HUMAN relationship: location_of CCO:B0055799 ! VAC14_HUMAN relationship: location_of CCO:B0055837 ! SMF_HUMAN relationship: location_of CCO:B0055842 ! TFCP2_HUMAN relationship: location_of CCO:B0055849 ! Q12843_HUMAN relationship: location_of CCO:B0055850 ! Q12845_HUMAN relationship: location_of CCO:B0055906 ! PM2L3_HUMAN relationship: location_of CCO:B0055926 ! Q13537_HUMAN relationship: location_of CCO:B0055971 ! RCAN2_HUMAN relationship: location_of CCO:B0055973 ! EPAG_HUMAN relationship: location_of CCO:B0056046 ! Q15142_HUMAN relationship: location_of CCO:B0056121 ! ZNF77_HUMAN relationship: location_of CCO:B0056126 ! Q16161_HUMAN relationship: location_of CCO:B0056134 ! Q16293_HUMAN relationship: location_of CCO:B0056138 ! SSX2_HUMAN relationship: location_of CCO:B0056147 ! Q16544_HUMAN relationship: location_of CCO:B0056174 ! Q16673_HUMAN relationship: location_of CCO:B0056240 ! P3H1_HUMAN relationship: location_of CCO:B0056356 ! QORX_HUMAN relationship: location_of CCO:B0056418 ! TMM97_HUMAN relationship: location_of CCO:B0057268 ! COMD7_HUMAN relationship: location_of CCO:B0057428 ! S6OS1_HUMAN relationship: location_of CCO:B0057456 ! ZN664_HUMAN relationship: location_of CCO:B0057532 ! ABTB2_HUMAN relationship: location_of CCO:B0057896 ! RIN3_HUMAN relationship: location_of CCO:B0058060 ! SHC3_HUMAN relationship: location_of CCO:B0058113 ! Q92942_HUMAN relationship: location_of CCO:B0058189 ! RHES_HUMAN relationship: location_of CCO:B0058235 ! ITCH_HUMAN relationship: location_of CCO:B0058387 ! AXUD1_HUMAN relationship: location_of CCO:B0058474 ! RETNB_HUMAN relationship: location_of CCO:B0058479 ! SOST_HUMAN relationship: location_of CCO:B0058575 ! Q9BYD4_HUMAN relationship: location_of CCO:B0058582 ! PBX4_HUMAN relationship: location_of CCO:B0058601 ! GPR62_HUMAN relationship: location_of CCO:B0058602 ! GPR61_HUMAN relationship: location_of CCO:B0058603 ! Q9BZL0_HUMAN relationship: location_of CCO:B0058629 ! GPR88_HUMAN relationship: location_of CCO:B0058656 ! PHS2_HUMAN relationship: location_of CCO:B0058663 ! LPAR5_HUMAN relationship: location_of CCO:B0058686 ! CXXC4_HUMAN relationship: location_of CCO:B0058709 ! JHD3C_HUMAN relationship: location_of CCO:B0058774 ! SEBOX_HUMAN relationship: location_of CCO:B0058809 ! ZBT26_HUMAN relationship: location_of CCO:B0058818 ! PDE11_HUMAN relationship: location_of CCO:B0058831 ! Q9NP35_HUMAN relationship: location_of CCO:B0058839 ! CABP5_HUMAN relationship: location_of CCO:B0058841 ! RAB9B_HUMAN relationship: location_of CCO:B0058849 ! CD320_HUMAN relationship: location_of CCO:B0058870 ! Q9NQR6_HUMAN relationship: location_of CCO:B0058900 ! TULP4_HUMAN relationship: location_of CCO:B0058919 ! CISH_HUMAN relationship: location_of CCO:B0058969 ! KBRS2_HUMAN relationship: location_of CCO:B0058970 ! KBRS1_HUMAN relationship: location_of CCO:B0059013 ! VSX1_HUMAN relationship: location_of CCO:B0059018 ! LMCD1_HUMAN relationship: location_of CCO:B0059021 ! ZIM2_HUMAN relationship: location_of CCO:B0059062 ! IMPCT_HUMAN relationship: location_of CCO:B0059066 ! GALP_HUMAN relationship: location_of CCO:B0059084 ! DKK4_HUMAN relationship: location_of CCO:B0059100 ! Q9UDC8_HUMAN relationship: location_of CCO:B0059101 ! Q9UDC9_HUMAN relationship: location_of CCO:B0059102 ! Q9UDD7_HUMAN relationship: location_of CCO:B0059163 ! ZN107_HUMAN relationship: location_of CCO:B0059165 ! SPB13_HUMAN relationship: location_of CCO:B0059187 ! Q9UK67_HUMAN relationship: location_of CCO:B0059188 ! FEM1B_HUMAN relationship: location_of CCO:B0059210 ! CB029_HUMAN relationship: location_of CCO:B0059236 ! RAB26_HUMAN relationship: location_of CCO:B0059248 ! RHG26_HUMAN relationship: location_of CCO:B0059282 ! TENN_HUMAN relationship: location_of CCO:B0059305 ! SBNO2_HUMAN relationship: location_of CCO:B0059343 ! GRIP1_HUMAN relationship: location_of CCO:B0059363 ! GPSM3_HUMAN relationship: location_of CCO:B0059406 ! WSB1_HUMAN relationship: location_of CCO:B0062767 ! RWD2B_HUMAN relationship: location_of CCO:B0062845 ! RAI2_HUMAN relationship: location_of CCO:B0062893 ! SAM50_HUMAN relationship: location_of CCO:B0062948 ! CHAC1_HUMAN relationship: location_of CCO:B0063028 ! OIP5_HUMAN relationship: location_of CCO:B0063184 ! MYG1_HUMAN relationship: location_of CCO:B0063206 ! HSP77_HUMAN relationship: location_of CCO:B0063224 ! INSL6_HUMAN relationship: location_of CCO:B0063314 ! HSN2_HUMAN relationship: location_of CCO:B0063385 ! RM44_HUMAN relationship: location_of CCO:B0063467 ! OFD1_HUMAN relationship: location_of CCO:B0063532 ! APMAP_HUMAN relationship: location_of CCO:B0063544 ! ARHG8_HUMAN-Phosphoserine106 relationship: location_of CCO:B0063588 ! ARI4B_HUMAN-Phosphoserine1159 relationship: location_of CCO:B0063701 ! BAG3_HUMAN-Phosphothreonine285 relationship: location_of CCO:B0063794 ! BCL7A_HUMAN-Phosphoserine203 relationship: location_of CCO:B0063908 ! BI2L1_HUMAN-Phosphoserine331 relationship: location_of CCO:B0064025 ! C5ARL_HUMAN-Phosphoserine326 relationship: location_of CCO:B0064214 ! CDCA3_HUMAN-Phosphothreonine37 relationship: location_of CCO:B0064244 ! CDV3_HUMAN-Phosphoserine25 relationship: location_of CCO:B0064300 ! CFDP1_HUMAN-Phosphoserine250 relationship: location_of CCO:B0064392 ! CLSPN_HUMAN-Phosphoserine83 relationship: location_of CCO:B0064632 ! DAPP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0064694 ! DDX1_HUMAN-Phosphotyrosine628 relationship: location_of CCO:B0064711 ! DDX24_HUMAN-Phosphoserine295 relationship: location_of CCO:B0064740 ! DEPD7_HUMAN-Phosphoserine152 relationship: location_of CCO:B0064790 ! DMWD_HUMAN-Phosphoserine545 relationship: location_of CCO:B0065494 ! AIDA_HUMAN-Phosphoserine144 relationship: location_of CCO:B0065565 ! AKP13_HUMAN-Phosphoserine1929 relationship: location_of CCO:B0065783 ! ATX2L_HUMAN-Phosphoserine559 relationship: location_of CCO:B0065798 ! BL1S1_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0065799 ! BR44L_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065804 ! C43BP_HUMAN-Phosphoserine377 relationship: location_of CCO:B0065820 ! CASC3_HUMAN-Phosphoserine363 relationship: location_of CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0066218 ! FMNL_HUMAN-Phosphoserine184 relationship: location_of CCO:B0066229 ! FN3K_HUMAN-Phosphoserine258 relationship: location_of CCO:B0066362 ! GALA_HUMAN-Phosphoserine117 relationship: location_of CCO:B0066560 ! GPTC8_HUMAN-Phosphothreonine242 relationship: location_of CCO:B0066889 ! HOME3_HUMAN-Phosphoserine159 relationship: location_of CCO:B0066934 ! HSPB8_HUMAN-Phosphoserine24 relationship: location_of CCO:B0067093 ! INADL_HUMAN-Phosphoserine455 relationship: location_of CCO:B0067186 ! JAD1C_HUMAN-Phosphoserine317 relationship: location_of CCO:B0068256 ! MPIP3_HUMAN-Phosphoserine57 relationship: location_of CCO:B0068321 ! MTPN_HUMAN-N-acetylcysteine2 relationship: location_of CCO:B0068528 ! NDK5_HUMAN-Phosphotyrosine58 relationship: location_of CCO:B0068967 ! OGFR_HUMAN-Phosphoserine484 relationship: location_of CCO:B0069183 ! PDE5A_HUMAN-Phosphoserine102 relationship: location_of CCO:B0069272 ! PHIP_HUMAN-Phosphoserine1315 relationship: location_of CCO:B0069282 ! PHLP_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069309 ! PIMT_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0069331 ! PKHA5_HUMAN-Phosphotyrosine134 relationship: location_of CCO:B0069399 ! PLCH2_HUMAN-Phosphoserine605 relationship: location_of CCO:B0069421 ! PLXA1_HUMAN-Phosphotyrosine122 relationship: location_of CCO:B0069428 ! PM2LB_HUMAN-Phosphotyrosine10 relationship: location_of CCO:B0069587 ! PTAD1_HUMAN-Phosphoserine114 relationship: location_of CCO:B0069671 ! RAB18_HUMAN-Phosphothreonine29 relationship: location_of CCO:B0069760 ! RB39A_HUMAN-Cysteine methyl ester217 relationship: location_of CCO:B0069910 ! RGL2_HUMAN-Phosphoserine13 relationship: location_of CCO:B0069922 ! RGS7_HUMAN-Phosphoserine229 relationship: location_of CCO:B0070013 ! RHOJ_HUMAN-Cysteine methyl ester211 relationship: location_of CCO:B0070054 ! RIN2_HUMAN-Phosphothreonine509 relationship: location_of CCO:B0070256 ! RTKN_HUMAN-Phosphoserine543 relationship: location_of CCO:B0070394 ! SF17A_HUMAN-Phosphoserine633 relationship: location_of CCO:B0070479 ! SHAN2_HUMAN-Phosphoserine1113 relationship: location_of CCO:B0070734 ! SON_HUMAN-Phosphoserine1784 relationship: location_of CCO:B0071002 ! SURF2_HUMAN-Phosphothreonine195 relationship: location_of CCO:B0071437 ! TNAP1_HUMAN-Phosphoserine280 relationship: location_of CCO:B0071574 ! TRIPC_HUMAN-Phosphoserine997 relationship: location_of CCO:B0071666 ! UBC12_HUMAN-Phosphoserine50 relationship: location_of CCO:B0071709 ! UC5IP_HUMAN-Phosphoserine16 relationship: location_of CCO:B0071741 ! US6NL_HUMAN-Phosphoserine391 relationship: location_of CCO:B0071928 ! YLPM1_HUMAN-Phosphoserine634 relationship: location_of CCO:B0072044 ! ZMYM2_HUMAN-Phosphoserine305 [Term] id: CCO:C0000201 name: extracellular region namespace: cellular_component def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] comment: Note that this term is intended to annotate gene products that are not uniformly attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "extracellular" EXACT [] xref: GO:0005576 is_a: CCO:C0000200 ! cellular_component relationship: location_of CCO:B0001362 ! EREG_HUMAN relationship: location_of CCO:B0001379 ! FGF10_HUMAN relationship: location_of CCO:B0001383 ! KLK10_HUMAN relationship: location_of CCO:B0001402 ! VEGFD_HUMAN relationship: location_of CCO:B0001448 ! TNF15_HUMAN relationship: location_of CCO:B0001469 ! PDGFB_HUMAN relationship: location_of CCO:B0001470 ! EGF_HUMAN relationship: location_of CCO:B0001471 ! TGFB1_HUMAN relationship: location_of CCO:B0001472 ! IGF2_HUMAN relationship: location_of CCO:B0001473 ! TNFB_HUMAN relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0001475 ! IL1A_HUMAN relationship: location_of CCO:B0001476 ! IL1B_HUMAN relationship: location_of CCO:B0001480 ! PDGFA_HUMAN relationship: location_of CCO:B0001484 ! IFNW1_HUMAN relationship: location_of CCO:B0001485 ! INHA_HUMAN relationship: location_of CCO:B0001498 ! INHBA_HUMAN relationship: location_of CCO:B0001500 ! FGF4_HUMAN relationship: location_of CCO:B0001502 ! FGF2_HUMAN relationship: location_of CCO:B0001504 ! IL8_HUMAN relationship: location_of CCO:B0001507 ! TGFB3_HUMAN relationship: location_of CCO:B0001509 ! FGF6_HUMAN relationship: location_of CCO:B0001511 ! FGF3_HUMAN relationship: location_of CCO:B0001514 ! FGF5_HUMAN relationship: location_of CCO:B0001515 ! BMP2_HUMAN relationship: location_of CCO:B0001516 ! BMP4_HUMAN relationship: location_of CCO:B0001531 ! BMP7_HUMAN relationship: location_of CCO:B0001541 ! PTN_HUMAN relationship: location_of CCO:B0001544 ! MK_HUMAN relationship: location_of CCO:B0001545 ! FGF7_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0001583 ! FGF9_HUMAN relationship: location_of CCO:B0001590 ! BTC_HUMAN relationship: location_of CCO:B0001607 ! NBL1_HUMAN relationship: location_of CCO:B0001633 ! PLGF_HUMAN relationship: location_of CCO:B0001634 ! VEGFB_HUMAN relationship: location_of CCO:B0001635 ! VEGFC_HUMAN relationship: location_of CCO:B0001674 ! FGF8_HUMAN relationship: location_of CCO:B0001683 ! PROK1_HUMAN relationship: location_of CCO:B0001687 ! TGFB2_HUMAN relationship: location_of CCO:B0001791 ! LTBP2_HUMAN relationship: location_of CCO:B0001931 ! VASH1_HUMAN relationship: location_of CCO:B0001947 ! EGFL6_HUMAN relationship: location_of CCO:B0002120 ! PDGFD_HUMAN relationship: location_of CCO:B0002164 ! GKN1_HUMAN relationship: location_of CCO:B0002197 ! DMBT1_HUMAN relationship: location_of CCO:B0005205 ! IL1F5_HUMAN relationship: location_of CCO:B0005215 ! FBLN4_HUMAN relationship: location_of CCO:B0005328 ! NOGG_HUMAN relationship: location_of CCO:B0005427 ! NELL2_HUMAN relationship: location_of CCO:B0005447 ! NRP1_HUMAN relationship: location_of CCO:B0005479 ! TNR6_HUMAN relationship: location_of CCO:B0005534 ! TNR1A_HUMAN relationship: location_of CCO:B0005535 ! TNR1B_HUMAN relationship: location_of CCO:B0005572 ! GNPTG_HUMAN relationship: location_of CCO:B0005646 ! FGFP1_HUMAN relationship: location_of CCO:B0005870 ! TGFA_HUMAN relationship: location_of CCO:B0005875 ! CD59_HUMAN relationship: location_of CCO:B0005949 ! AGRIN_HUMAN relationship: location_of CCO:B0005955 ! FBLN3_HUMAN relationship: location_of CCO:B0005958 ! EGFL7_HUMAN relationship: location_of CCO:B0005959 ! FBLN1_HUMAN relationship: location_of CCO:B0005961 ! GRN_HUMAN relationship: location_of CCO:B0005964 ! PGBM_HUMAN relationship: location_of CCO:B0005967 ! LAMB1_HUMAN relationship: location_of CCO:B0005973 ! NELL1_HUMAN relationship: location_of CCO:B0005989 ! FBLN5_HUMAN relationship: location_of CCO:B0006047 ! WNT16_HUMAN relationship: location_of CCO:B0006081 ! CBPE_HUMAN relationship: location_of CCO:B0006087 ! CCL18_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0006157 ! PSG9_HUMAN relationship: location_of CCO:B0006168 ! IGS21_HUMAN relationship: location_of CCO:B0006180 ! GDF9_HUMAN relationship: location_of CCO:B0006193 ! VTDB_HUMAN relationship: location_of CCO:B0006263 ! GLHA_HUMAN relationship: location_of CCO:B0006308 ! WFDC2_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0006339 ! DEF1_HUMAN relationship: location_of CCO:B0006345 ! CATB_HUMAN relationship: location_of CCO:B0010371 ! 1433S_HUMAN-Phosphoserine216 relationship: location_of CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: location_of CCO:B0010459 ! ADAM9_HUMAN-Phosphothreonine761 relationship: location_of CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 relationship: location_of CCO:B0010556 ! ANXA2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0011876 ! FGF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011879 ! FGFR2_HUMAN-Phosphotyrosine657 relationship: location_of CCO:B0012184 ! HGF_HUMAN-Pyrrolidone carboxylic acid32 relationship: location_of CCO:B0012658 ! LAMA4_HUMAN-Phosphotyrosine1593 relationship: location_of CCO:B0012697 ! LEPR_HUMAN-Phosphotyrosine1141 relationship: location_of CCO:B0013374 ! PACA_HUMAN-Lysine amide169 relationship: location_of CCO:B0013601 ! PPIA_HUMAN-Phosphoserine21 relationship: location_of CCO:B0014248 ! STC2_HUMAN-Phosphothreonine28 relationship: location_of CCO:B0014355 ! THRB_HUMAN-4-carboxyglutamate59 relationship: location_of CCO:B0014388 ! TKNK_HUMAN-Methionine amide90 relationship: location_of CCO:B0014612 ! VEGFA_HUMAN-N6-acetyllysine152 relationship: location_of CCO:B0014615 ! VGFR1_HUMAN-Phosphotyrosine1213 relationship: location_of CCO:B0014899 ! IPSP_HUMAN relationship: location_of CCO:B0014946 ! EPHAA_HUMAN relationship: location_of CCO:B0015164 ! HHIP_HUMAN relationship: location_of CCO:B0015673 ! CHL1_HUMAN relationship: location_of CCO:B0015779 ! PILRA_HUMAN relationship: location_of CCO:B0015956 ! IFNK_HUMAN relationship: location_of CCO:B0015966 ! IFNB_HUMAN relationship: location_of CCO:B0015973 ! IFNA2_HUMAN relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0017123 ! PROK2_HUMAN relationship: location_of CCO:B0017141 ! NEU1_HUMAN relationship: location_of CCO:B0017509 ! FGF20_HUMAN relationship: location_of CCO:B0017511 ! FGF22_HUMAN relationship: location_of CCO:B0017671 ! FGF16_HUMAN relationship: location_of CCO:B0018717 ! Q9UK79_HUMAN relationship: location_of CCO:B0019657 ! ATL4_HUMAN relationship: location_of CCO:B0019689 ! ATS1_HUMAN relationship: location_of CCO:B0019703 ! Q59FE5_HUMAN relationship: location_of CCO:B0020115 ! ANGL5_HUMAN relationship: location_of CCO:B0020122 ! FCN1_HUMAN relationship: location_of CCO:B0020123 ! MFAP4_HUMAN relationship: location_of CCO:B0021671 ! HBEGF_HUMAN relationship: location_of CCO:B0021692 ! WISP1_HUMAN relationship: location_of CCO:B0021695 ! Q6PEG3_HUMAN relationship: location_of CCO:B0021696 ! CTGF_HUMAN relationship: location_of CCO:B0021697 ! NOV_HUMAN relationship: location_of CCO:B0021699 ! WISP2_HUMAN relationship: location_of CCO:B0021887 ! I17RB_HUMAN relationship: location_of CCO:B0022985 ! FGF17_HUMAN relationship: location_of CCO:B0022986 ! FGF18_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0024051 ! ADEC1_HUMAN relationship: location_of CCO:B0024369 ! IL7_HUMAN relationship: location_of CCO:B0024617 ! MMP2_HUMAN relationship: location_of CCO:B0024704 ! PPA6_HUMAN relationship: location_of CCO:B0025184 ! IL6RB_HUMAN relationship: location_of CCO:B0026670 ! TICN1_HUMAN relationship: location_of CCO:B0027449 ! TINAL_HUMAN relationship: location_of CCO:B0027571 ! SLIT2_HUMAN relationship: location_of CCO:B0028166 ! A1AT_HUMAN relationship: location_of CCO:B0028290 ! JAG1_HUMAN relationship: location_of CCO:B0028292 ! DLL1_HUMAN relationship: location_of CCO:B0028600 ! APOA1_HUMAN relationship: location_of CCO:B0029727 ! CEAM1_HUMAN relationship: location_of CCO:B0031622 ! CDD_HUMAN relationship: location_of CCO:B0031667 ! RSPO2_HUMAN relationship: location_of CCO:B0031669 ! RSPO1_HUMAN relationship: location_of CCO:B0031672 ! RSPO4_HUMAN relationship: location_of CCO:B0031673 ! RSPO3_HUMAN relationship: location_of CCO:B0031787 ! NOE2_HUMAN relationship: location_of CCO:B0031800 ! OLFL3_HUMAN relationship: location_of CCO:B0031813 ! IFNG_HUMAN relationship: location_of CCO:B0031878 ! VWF_HUMAN relationship: location_of CCO:B0031949 ! FINC_HUMAN relationship: location_of CCO:B0032721 ! BDNF_HUMAN relationship: location_of CCO:B0032938 ! ANGT_HUMAN relationship: location_of CCO:B0033477 ! LRP8_HUMAN relationship: location_of CCO:B0033567 ! GHRL_HUMAN relationship: location_of CCO:B0034258 ! GAS6_HUMAN relationship: location_of CCO:B0034291 ! IGHG3_HUMAN relationship: location_of CCO:B0034532 ! AMD_HUMAN-Phosphoserine955 relationship: location_of CCO:B0034581 ! ATS8_HUMAN-Phosphotyrosine255 relationship: location_of CCO:B0034734 ! EPHA3_HUMAN-Phosphotyrosine596 relationship: location_of CCO:B0035212 ! MP2K2_HUMAN-Phosphothreonine394 relationship: location_of CCO:B0035783 ! TICN2_HUMAN-Phosphothreonine86 relationship: location_of CCO:B0035955 ! CXCL7_HUMAN relationship: location_of CCO:B0036109 ! CO3_HUMAN relationship: location_of CCO:B0037954 ! 7B2_HUMAN relationship: location_of CCO:B0038579 ! CBPZ_HUMAN relationship: location_of CCO:B0038671 ! REL1_HUMAN relationship: location_of CCO:B0038734 ! DPP4_HUMAN relationship: location_of CCO:B0038878 ! CSF1_HUMAN relationship: location_of CCO:B0038963 ! CCL7_HUMAN relationship: location_of CCO:B0038969 ! CCL11_HUMAN relationship: location_of CCO:B0039075 ! INHBB_HUMAN relationship: location_of CCO:B0039305 ! ADCK1_HUMAN-Phosphothreonine441 relationship: location_of CCO:B0039348 ! CCL13_HUMAN-acid24 relationship: location_of CCO:B0039349 ! CCL2_HUMAN-Pyrrolidone carboxylic acid24 relationship: location_of CCO:B0039351 ! CCL8_HUMAN-Pyrrolidone carboxylic acid24 relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039858 ! KLK8_HUMAN relationship: location_of CCO:B0039862 ! KLK6_HUMAN relationship: location_of CCO:B0041187 ! SCG1_HUMAN-Sulfotyrosine471 relationship: location_of CCO:B0041664 ! PLF4_HUMAN relationship: location_of CCO:B0041666 ! CXCL5_HUMAN relationship: location_of CCO:B0041668 ! GROA_HUMAN relationship: location_of CCO:B0041670 ! CXCL6_HUMAN relationship: location_of CCO:B0041769 ! APOL3_HUMAN relationship: location_of CCO:B0042116 ! GDF5_HUMAN relationship: location_of CCO:B0042120 ! NODAL_HUMAN relationship: location_of CCO:B0042127 ! BMP10_HUMAN relationship: location_of CCO:B0042130 ! BMP6_HUMAN relationship: location_of CCO:B0043821 ! IGF1B_HUMAN relationship: location_of CCO:B0043822 ! EDN1_HUMAN relationship: location_of CCO:B0043823 ! EDN3_HUMAN relationship: location_of CCO:B0043824 ! IL12B_HUMAN relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0048872 ! ALS_HUMAN relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0049576 ! NRG1_HUMAN relationship: location_of CCO:B0049672 ! TPO_HUMAN relationship: location_of CCO:B0049674 ! Q5FBX8_HUMAN relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0050218 ! TENA_HUMAN relationship: location_of CCO:B0050820 ! NT2NL_HUMAN relationship: location_of CCO:B0051192 ! CNPY4_HUMAN relationship: location_of CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0052404 ! GELS_HUMAN-Phosphotyrosine603 relationship: location_of CCO:B0052719 ! S10A7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0053803 ! A6NE61_HUMAN relationship: location_of CCO:B0053810 ! A6NEV2_HUMAN relationship: location_of CCO:B0053953 ! A8K0G1_HUMAN relationship: location_of CCO:B0054223 ! B1AJZ6_HUMAN relationship: location_of CCO:B0054295 ! CCL24_HUMAN relationship: location_of CCO:B0054296 ! LEG9_HUMAN relationship: location_of CCO:B0054303 ! AGRP_HUMAN relationship: location_of CCO:B0054308 ! LFTY2_HUMAN relationship: location_of CCO:B0054310 ! TR11B_HUMAN relationship: location_of CCO:B0054334 ! CCL21_HUMAN relationship: location_of CCO:B0054337 ! CYR61_HUMAN relationship: location_of CCO:B0054338 ! CCL22_HUMAN relationship: location_of CCO:B0054340 ! WN10B_HUMAN relationship: location_of CCO:B0054341 ! WNT7A_HUMAN relationship: location_of CCO:B0054346 ! NRG2_HUMAN relationship: location_of CCO:B0054356 ! GBGT2_HUMAN relationship: location_of CCO:B0054359 ! CXL11_HUMAN relationship: location_of CCO:B0054375 ! TNF11_HUMAN relationship: location_of CCO:B0054376 ! GDF8_HUMAN relationship: location_of CCO:B0054388 ! WNT9A_HUMAN relationship: location_of CCO:B0054389 ! WNT9B_HUMAN relationship: location_of CCO:B0054408 ! ANGP2_HUMAN relationship: location_of CCO:B0054410 ! MYT2_HUMAN relationship: location_of CCO:B0054418 ! LAMA5_HUMAN relationship: location_of CCO:B0054421 ! DEFB2_HUMAN relationship: location_of CCO:B0054430 ! CHAD_HUMAN relationship: location_of CCO:B0054436 ! CCL25_HUMAN relationship: location_of CCO:B0054451 ! PLXB1_HUMAN relationship: location_of CCO:B0054464 ! O43266_HUMAN relationship: location_of CCO:B0054484 ! TNF12_HUMAN relationship: location_of CCO:B0054486 ! O43532_HUMAN relationship: location_of CCO:B0054490 ! TNF14_HUMAN relationship: location_of CCO:B0054522 ! ANGL7_HUMAN relationship: location_of CCO:B0054617 ! CILP1_HUMAN relationship: location_of CCO:B0054631 ! DEAF1_HUMAN relationship: location_of CCO:B0054636 ! USH2A_HUMAN relationship: location_of CCO:B0054643 ! GPC4_HUMAN relationship: location_of CCO:B0054657 ! LFTY1_HUMAN relationship: location_of CCO:B0054660 ! CREG1_HUMAN relationship: location_of CCO:B0054672 ! LECT1_HUMAN relationship: location_of CCO:B0054674 ! TNF13_HUMAN relationship: location_of CCO:B0054709 ! DKK1_HUMAN relationship: location_of CCO:B0054728 ! NXPH2_HUMAN relationship: location_of CCO:B0054729 ! NXPH3_HUMAN relationship: location_of CCO:B0054730 ! NXPH4_HUMAN relationship: location_of CCO:B0054755 ! WISP3_HUMAN relationship: location_of CCO:B0054756 ! GDF11_HUMAN relationship: location_of CCO:B0054760 ! TNR6B_HUMAN relationship: location_of CCO:B0054765 ! GNAS3_HUMAN relationship: location_of CCO:B0054777 ! NET1_HUMAN relationship: location_of CCO:B0054778 ! FSTL3_HUMAN relationship: location_of CCO:B0054784 ! LY86_HUMAN relationship: location_of CCO:B0054788 ! O95740_HUMAN relationship: location_of CCO:B0054795 ! CER1_HUMAN relationship: location_of CCO:B0054799 ! ANGL1_HUMAN relationship: location_of CCO:B0054808 ! O95958_HUMAN relationship: location_of CCO:B0054809 ! ITGBL_HUMAN relationship: location_of CCO:B0054810 ! LGI1_HUMAN relationship: location_of CCO:B0054822 ! WNT11_HUMAN relationship: location_of CCO:B0054825 ! LALBA_HUMAN relationship: location_of CCO:B0054826 ! PLMN_HUMAN relationship: location_of CCO:B0054827 ! UROK_HUMAN relationship: location_of CCO:B0054828 ! RENI_HUMAN relationship: location_of CCO:B0054830 ! CO5_HUMAN relationship: location_of CCO:B0054831 ! TIMP1_HUMAN relationship: location_of CCO:B0054836 ! PENK_HUMAN relationship: location_of CCO:B0054837 ! PDYN_HUMAN relationship: location_of CCO:B0054838 ! TSHB_HUMAN relationship: location_of CCO:B0054839 ! FSHB_HUMAN relationship: location_of CCO:B0054840 ! LSHB_HUMAN relationship: location_of CCO:B0054841 ! CGHB_HUMAN relationship: location_of CCO:B0054842 ! PRL_HUMAN relationship: location_of CCO:B0054844 ! CSH_HUMAN relationship: location_of CCO:B0054845 ! CALC_HUMAN relationship: location_of CCO:B0054847 ! PTHY_HUMAN relationship: location_of CCO:B0054850 ! SLIB_HUMAN relationship: location_of CCO:B0054852 ! INS_HUMAN relationship: location_of CCO:B0054853 ! IGF1A_HUMAN relationship: location_of CCO:B0054855 ! EPO_HUMAN relationship: location_of CCO:B0054856 ! CD8A_HUMAN relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054863 ! APOA2_HUMAN relationship: location_of CCO:B0054864 ! APOC3_HUMAN relationship: location_of CCO:B0054866 ! FIBB_HUMAN relationship: location_of CCO:B0054867 ! FIBG_HUMAN relationship: location_of CCO:B0054871 ! APOH_HUMAN relationship: location_of CCO:B0054872 ! AMBP_HUMAN relationship: location_of CCO:B0054874 ! ALBU_HUMAN relationship: location_of CCO:B0054875 ! CXL10_HUMAN relationship: location_of CCO:B0054883 ! PA21B_HUMAN relationship: location_of CCO:B0054884 ! PROC_HUMAN relationship: location_of CCO:B0054885 ! CSF2_HUMAN relationship: location_of CCO:B0054891 ! WNT1_HUMAN relationship: location_of CCO:B0054894 ! IL4_HUMAN relationship: location_of CCO:B0054895 ! IL5_HUMAN relationship: location_of CCO:B0054896 ! PAI2_HUMAN relationship: location_of CCO:B0054899 ! IL6_HUMAN relationship: location_of CCO:B0054902 ! AGAL_HUMAN relationship: location_of CCO:B0054907 ! CALCA_HUMAN relationship: location_of CCO:B0054908 ! GDN_HUMAN relationship: location_of CCO:B0054913 ! GRP_HUMAN relationship: location_of CCO:B0054917 ! UROM_HUMAN relationship: location_of CCO:B0054920 ! CO1A2_HUMAN relationship: location_of CCO:B0054926 ! ELNE_HUMAN relationship: location_of CCO:B0054928 ! CD14_HUMAN relationship: location_of CCO:B0054931 ! IL3_HUMAN relationship: location_of CCO:B0054933 ! IL6RA_HUMAN relationship: location_of CCO:B0054938 ! NMB_HUMAN relationship: location_of CCO:B0054941 ! DOPO_HUMAN relationship: location_of CCO:B0054944 ! SPRC_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0054948 ! GIP_HUMAN relationship: location_of CCO:B0054952 ! CSF3_HUMAN relationship: location_of CCO:B0054954 ! NPS_HUMAN relationship: location_of CCO:B0054970 ! CALCB_HUMAN relationship: location_of CCO:B0054972 ! CCL3_HUMAN relationship: location_of CCO:B0054980 ! CLUS_HUMAN relationship: location_of CCO:B0054983 ! CD8B_HUMAN relationship: location_of CCO:B0054985 ! LAMC1_HUMAN relationship: location_of CCO:B0054993 ! UTER_HUMAN relationship: location_of CCO:B0054999 ! PTHR_HUMAN relationship: location_of CCO:B0055002 ! GRAA_HUMAN relationship: location_of CCO:B0055006 ! ACE_HUMAN relationship: location_of CCO:B0055007 ! MOTI_HUMAN relationship: location_of CCO:B0055011 ! CCL4_HUMAN relationship: location_of CCO:B0055013 ! CCL5_HUMAN relationship: location_of CCO:B0055018 ! ONCM_HUMAN relationship: location_of CCO:B0055029 ! MMP9_HUMAN relationship: location_of CCO:B0055030 ! LIF_HUMAN relationship: location_of CCO:B0055032 ! IL9_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055046 ! TIMP2_HUMAN relationship: location_of CCO:B0055053 ! PRLR_HUMAN relationship: location_of CCO:B0055058 ! CL3L1_HUMAN relationship: location_of CCO:B0055059 ! ANFB_HUMAN relationship: location_of CCO:B0055094 ! IBP3_HUMAN relationship: location_of CCO:B0055098 ! IBP2_HUMAN relationship: location_of CCO:B0055111 ! FST_HUMAN relationship: location_of CCO:B0055114 ! CAP7_HUMAN relationship: location_of CCO:B0055119 ! TKN1_HUMAN relationship: location_of CCO:B0055120 ! MCH_HUMAN relationship: location_of CCO:B0055124 ! NTF3_HUMAN relationship: location_of CCO:B0055125 ! EDN2_HUMAN relationship: location_of CCO:B0055126 ! IL11_HUMAN relationship: location_of CCO:B0055135 ! SCF_HUMAN relationship: location_of CCO:B0055142 ! IL10_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055144 ! CCL1_HUMAN relationship: location_of CCO:B0055149 ! IBP4_HUMAN relationship: location_of CCO:B0055151 ! CPN2_HUMAN relationship: location_of CCO:B0055173 ! IBP6_HUMAN relationship: location_of CCO:B0055174 ! IBP5_HUMAN relationship: location_of CCO:B0055184 ! LAMA1_HUMAN relationship: location_of CCO:B0055188 ! TNR5_HUMAN relationship: location_of CCO:B0055190 ! PTX3_HUMAN relationship: location_of CCO:B0055193 ! CD27_HUMAN relationship: location_of CCO:B0055199 ! LYOX_HUMAN relationship: location_of CCO:B0055232 ! NEUT_HUMAN relationship: location_of CCO:B0055270 ! NTF4_HUMAN relationship: location_of CCO:B0055282 ! SFTPD_HUMAN relationship: location_of CCO:B0055297 ! TIMP3_HUMAN relationship: location_of CCO:B0055322 ! COIA1_HUMAN relationship: location_of CCO:B0055323 ! GDNF_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055333 ! LEP_HUMAN relationship: location_of CCO:B0055336 ! WNT5A_HUMAN relationship: location_of CCO:B0055347 ! ASIP_HUMAN relationship: location_of CCO:B0055355 ! LIFR_HUMAN relationship: location_of CCO:B0055397 ! XCL1_HUMAN relationship: location_of CCO:B0055398 ! TNFL6_HUMAN relationship: location_of CCO:B0055399 ! SDF1_HUMAN relationship: location_of CCO:B0055406 ! INAR2_HUMAN relationship: location_of CCO:B0055409 ! NMU_HUMAN relationship: location_of CCO:B0055413 ! CD97_HUMAN relationship: location_of CCO:B0055435 ! FLT3L_HUMAN relationship: location_of CCO:B0055455 ! TNF10_HUMAN relationship: location_of CCO:B0055502 ! STC1_HUMAN relationship: location_of CCO:B0055527 ! UCN1_HUMAN relationship: location_of CCO:B0055528 ! BMP3B_HUMAN relationship: location_of CCO:B0055537 ! CCL23_HUMAN relationship: location_of CCO:B0055548 ! WNT3_HUMAN relationship: location_of CCO:B0055549 ! WNT3A_HUMAN relationship: location_of CCO:B0055550 ! WNT4_HUMAN relationship: location_of CCO:B0055551 ! WNT7B_HUMAN relationship: location_of CCO:B0055564 ! CABP4_HUMAN relationship: location_of CCO:B0055595 ! DEFB1_HUMAN relationship: location_of CCO:B0055607 ! SMS_HUMAN relationship: location_of CCO:B0055613 ! NPC2_HUMAN relationship: location_of CCO:B0055645 ! X3CL1_HUMAN relationship: location_of CCO:B0055647 ! RELN_HUMAN relationship: location_of CCO:B0055653 ! CCL20_HUMAN relationship: location_of CCO:B0055655 ! D103A_HUMAN relationship: location_of CCO:B0055659 ! HTRA3_HUMAN relationship: location_of CCO:B0055661 ! OX26_HUMAN relationship: location_of CCO:B0055681 ! NDP_HUMAN relationship: location_of CCO:B0055686 ! IL9R_HUMAN relationship: location_of CCO:B0055691 ! ILRL1_HUMAN relationship: location_of CCO:B0055714 ! GUC2A_HUMAN relationship: location_of CCO:B0055723 ! UPAR_HUMAN relationship: location_of CCO:B0055738 ! MUC24_HUMAN relationship: location_of CCO:B0055766 ! REG3A_HUMAN relationship: location_of CCO:B0055782 ! COGA1_HUMAN relationship: location_of CCO:B0055783 ! CXCL9_HUMAN relationship: location_of CCO:B0055789 ! LG3BP_HUMAN relationship: location_of CCO:B0055795 ! FGL1_HUMAN relationship: location_of CCO:B0055848 ! FSTL1_HUMAN relationship: location_of CCO:B0055883 ! Q13169_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0055923 ! PNOC_HUMAN relationship: location_of CCO:B0055945 ! ENPP2_HUMAN relationship: location_of CCO:B0055957 ! IL18_HUMAN relationship: location_of CCO:B0055972 ! IL27B_HUMAN relationship: location_of CCO:B0055977 ! FGL2_HUMAN relationship: location_of CCO:B0056004 ! IHH_HUMAN relationship: location_of CCO:B0056006 ! INSL4_HUMAN relationship: location_of CCO:B0056043 ! RAGE_HUMAN relationship: location_of CCO:B0056059 ! ANGP1_HUMAN relationship: location_of CCO:B0056066 ! SHH_HUMAN relationship: location_of CCO:B0056127 ! ENOX2_HUMAN relationship: location_of CCO:B0056131 ! IBP7_HUMAN relationship: location_of CCO:B0056152 ! CART_HUMAN relationship: location_of CCO:B0056158 ! ECM1_HUMAN relationship: location_of CCO:B0056160 ! CTF1_HUMAN relationship: location_of CCO:B0056163 ! STX1A_HUMAN relationship: location_of CCO:B0056164 ! CCL14_HUMAN relationship: location_of CCO:B0056171 ! CCL15_HUMAN relationship: location_of CCO:B0056175 ! MIA_HUMAN relationship: location_of CCO:B0056226 ! VWC2_HUMAN relationship: location_of CCO:B0056240 ! P3H1_HUMAN relationship: location_of CCO:B0056257 ! Q3KR29_HUMAN relationship: location_of CCO:B0056258 ! Q3KR30_HUMAN relationship: location_of CCO:B0056271 ! Q3SY79_HUMAN relationship: location_of CCO:B0056277 ! Q3V4E3_HUMAN relationship: location_of CCO:B0056327 ! Q4VAJ4_HUMAN relationship: location_of CCO:B0056391 ! Q59FF1_HUMAN relationship: location_of CCO:B0056399 ! Q59G81_HUMAN relationship: location_of CCO:B0056450 ! Q5JBS6_HUMAN relationship: location_of CCO:B0056513 ! Q5JYX2_HUMAN relationship: location_of CCO:B0056575 ! SFRP5_HUMAN relationship: location_of CCO:B0056578 ! ARTN_HUMAN relationship: location_of CCO:B0056613 ! Q5TEH8_HUMAN relationship: location_of CCO:B0056733 ! SFRP4_HUMAN relationship: location_of CCO:B0056834 ! GDF6_HUMAN relationship: location_of CCO:B0056927 ! APOA5_HUMAN relationship: location_of CCO:B0056970 ! SOSD1_HUMAN relationship: location_of CCO:B0057051 ! Q6ZS96_HUMAN relationship: location_of CCO:B0057053 ! Q6ZSD0_HUMAN relationship: location_of CCO:B0057057 ! Q6ZSP0_HUMAN relationship: location_of CCO:B0057108 ! ATS13_HUMAN relationship: location_of CCO:B0057317 ! IL29_HUMAN relationship: location_of CCO:B0057330 ! AEBP1_HUMAN relationship: location_of CCO:B0057344 ! HUNIN_HUMAN relationship: location_of CCO:B0057365 ! CNTN4_HUMAN relationship: location_of CCO:B0057369 ! SACA3_HUMAN relationship: location_of CCO:B0057439 ! Q8N294_HUMAN relationship: location_of CCO:B0057442 ! Q8N2D3_HUMAN relationship: location_of CCO:B0057449 ! LTBP4_HUMAN relationship: location_of CCO:B0057450 ! AGGF1_HUMAN relationship: location_of CCO:B0057464 ! SFRP1_HUMAN relationship: location_of CCO:B0057486 ! IGSF1_HUMAN relationship: location_of CCO:B0057487 ! LIRA3_HUMAN relationship: location_of CCO:B0057497 ! NPW_HUMAN relationship: location_of CCO:B0057526 ! BMPER_HUMAN relationship: location_of CCO:B0057558 ! PCSK9_HUMAN relationship: location_of CCO:B0057596 ! IL27A_HUMAN relationship: location_of CCO:B0057612 ! NPB_HUMAN relationship: location_of CCO:B0057884 ! ANGL6_HUMAN relationship: location_of CCO:B0057996 ! SCTM1_HUMAN relationship: location_of CCO:B0058002 ! ITLN1_HUMAN relationship: location_of CCO:B0058006 ! ITLN2_HUMAN relationship: location_of CCO:B0058010 ! IBPL1_HUMAN relationship: location_of CCO:B0058044 ! Q8WYK7_HUMAN relationship: location_of CCO:B0058067 ! CCL17_HUMAN relationship: location_of CCO:B0058087 ! HTRA1_HUMAN relationship: location_of CCO:B0058090 ! SFRP3_HUMAN relationship: location_of CCO:B0058102 ! EDA_HUMAN relationship: location_of CCO:B0058115 ! PRG4_HUMAN relationship: location_of CCO:B0058121 ! TNR25_HUMAN relationship: location_of CCO:B0058124 ! WNT2B_HUMAN relationship: location_of CCO:B0058125 ! WNT8B_HUMAN relationship: location_of CCO:B0058132 ! CS010_HUMAN relationship: location_of CCO:B0058134 ! I22R2_HUMAN relationship: location_of CCO:B0058148 ! TIP39_HUMAN relationship: location_of CCO:B0058169 ! FAM3D_HUMAN relationship: location_of CCO:B0058221 ! SFRP2_HUMAN relationship: location_of CCO:B0058226 ! KAZD1_HUMAN relationship: location_of CCO:B0058356 ! SG3A1_HUMAN relationship: location_of CCO:B0058407 ! CSF3R_HUMAN relationship: location_of CCO:B0058448 ! CCL19_HUMAN relationship: location_of CCO:B0058453 ! NRTN_HUMAN relationship: location_of CCO:B0058465 ! SEM3C_HUMAN relationship: location_of CCO:B0058466 ! GDF15_HUMAN relationship: location_of CCO:B0058474 ! RETNB_HUMAN relationship: location_of CCO:B0058479 ! SOST_HUMAN relationship: location_of CCO:B0058518 ! CRDL1_HUMAN relationship: location_of CCO:B0058555 ! C1QT2_HUMAN relationship: location_of CCO:B0058562 ! PAPP2_HUMAN relationship: location_of CCO:B0058565 ! EMR3_HUMAN relationship: location_of CCO:B0058572 ! ANGL4_HUMAN relationship: location_of CCO:B0058578 ! ACE2_HUMAN relationship: location_of CCO:B0058590 ! CNTP3_HUMAN relationship: location_of CCO:B0058636 ! WN10A_HUMAN relationship: location_of CCO:B0058640 ! FGF23_HUMAN relationship: location_of CCO:B0058642 ! IL22_HUMAN relationship: location_of CCO:B0058643 ! TWSG1_HUMAN relationship: location_of CCO:B0058665 ! WNT8A_HUMAN relationship: location_of CCO:B0058666 ! WNT5B_HUMAN relationship: location_of CCO:B0058691 ! CLC4M_HUMAN relationship: location_of CCO:B0058710 ! Q9H3R7_HUMAN relationship: location_of CCO:B0058739 ! GREM2_HUMAN relationship: location_of CCO:B0058783 ! IL21_HUMAN relationship: location_of CCO:B0058798 ! WFDC1_HUMAN relationship: location_of CCO:B0058829 ! CD209_HUMAN relationship: location_of CCO:B0058842 ! TREM1_HUMAN relationship: location_of CCO:B0058853 ! IL1AP_HUMAN relationship: location_of CCO:B0058859 ! ESM1_HUMAN relationship: location_of CCO:B0058862 ! ISK5_HUMAN relationship: location_of CCO:B0058891 ! TLR9_HUMAN relationship: location_of CCO:B0058902 ! CYTL1_HUMAN relationship: location_of CCO:B0058912 ! FGF21_HUMAN relationship: location_of CCO:B0058987 ! IL20_HUMAN relationship: location_of CCO:B0059031 ! IL17C_HUMAN relationship: location_of CCO:B0059066 ! GALP_HUMAN relationship: location_of CCO:B0059068 ! XCL2_HUMAN relationship: location_of CCO:B0059069 ! CLCF1_HUMAN relationship: location_of CCO:B0059080 ! DKK3_HUMAN relationship: location_of CCO:B0059082 ! CKLF_HUMAN relationship: location_of CCO:B0059084 ! DKK4_HUMAN relationship: location_of CCO:B0059085 ! DKK2_HUMAN relationship: location_of CCO:B0059103 ! Q9UDF1_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059136 ! IL19_HUMAN relationship: location_of CCO:B0059139 ! PCSK1_HUMAN relationship: location_of CCO:B0059157 ! Q9UID7_HUMAN relationship: location_of CCO:B0059171 ! METRN_HUMAN relationship: location_of CCO:B0059181 ! GDF2_HUMAN relationship: location_of CCO:B0059182 ! GBG8_HUMAN relationship: location_of CCO:B0059204 ! ANGL2_HUMAN relationship: location_of CCO:B0059243 ! NENF_HUMAN relationship: location_of CCO:B0059291 ! CLC11_HUMAN relationship: location_of CCO:B0059292 ! CCL26_HUMAN relationship: location_of CCO:B0059294 ! ANGP4_HUMAN relationship: location_of CCO:B0059296 ! TN13B_HUMAN relationship: location_of CCO:B0059337 ! GBG5L_HUMAN relationship: location_of CCO:B0059377 ! ANGL3_HUMAN relationship: location_of CCO:B0059387 ! TNR18_HUMAN relationship: location_of CCO:B0059389 ! WIF1_HUMAN relationship: location_of CCO:B0059405 ! WNT6_HUMAN relationship: location_of CCO:B0059423 ! LY96_HUMAN relationship: location_of CCO:B0062887 ! CETP_HUMAN relationship: location_of CCO:B0062944 ! Q96IH6_HUMAN relationship: location_of CCO:B0062971 ! ISK7_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0063007 ! ANTR2_HUMAN relationship: location_of CCO:B0063044 ! SLPI_HUMAN relationship: location_of CCO:B0063047 ! LYSC_HUMAN relationship: location_of CCO:B0063118 ! LEG7_HUMAN relationship: location_of CCO:B0063170 ! DCD_HUMAN relationship: location_of CCO:B0063191 ! GREM1_HUMAN relationship: location_of CCO:B0063197 ! MUC13_HUMAN relationship: location_of CCO:B0063209 ! CALU_HUMAN relationship: location_of CCO:B0063224 ! INSL6_HUMAN relationship: location_of CCO:B0063254 ! IL33_HUMAN relationship: location_of CCO:B0063273 ! GHR_HUMAN relationship: location_of CCO:B0063294 ! IL1RA_HUMAN relationship: location_of CCO:B0063314 ! HSN2_HUMAN relationship: location_of CCO:B0063321 ! CYTC_HUMAN relationship: location_of CCO:B0063322 ! ENTP6_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0063339 ! EMID2_HUMAN relationship: location_of CCO:B0063343 ! MUC7_HUMAN relationship: location_of CCO:B0063374 ! TTHY_HUMAN relationship: location_of CCO:B0063404 ! APOM_HUMAN relationship: location_of CCO:B0063428 ! PRG2_HUMAN relationship: location_of CCO:B0063433 ! EDEM2_HUMAN relationship: location_of CCO:B0063440 ! RNAS6_HUMAN relationship: location_of CCO:B0063443 ! LIPL_HUMAN relationship: location_of CCO:B0063876 ! BGH3_HUMAN-4-carboxyglutamate131 relationship: location_of CCO:B0064111 ! CCKN_HUMAN-Sulfotyrosine97 relationship: location_of CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0064445 ! CO4A3_HUMAN-Phosphoserine1437 relationship: location_of CCO:B0064446 ! CO4A4_HUMAN-Phosphoserine139 relationship: location_of CCO:B0064466 ! CRF_HUMAN-Isoleucine amide194 relationship: location_of CCO:B0064467 ! CRIM1_HUMAN-Phosphothreonine1035 relationship: location_of CCO:B0065034 ! ELN_HUMAN-4-hydroxyproline677 relationship: location_of CCO:B0065098 ! EPOR_HUMAN-Phosphotyrosine504 relationship: location_of CCO:B0065416 ! ADIPO_HUMAN-5-hydroxylysine65 relationship: location_of CCO:B0065425 ! ADML_HUMAN-Tyrosine amide146 relationship: location_of CCO:B0065689 ! APEL_HUMAN-Pyrrolidone carboxylic acid65 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: location_of CCO:B0066008 ! ENOX1_HUMAN-Phosphoserine403 relationship: location_of CCO:B0066072 ! FA10_HUMAN-4-carboxyglutamate79 relationship: location_of CCO:B0066109 ! FA7_HUMAN-4-carboxyglutamate85 relationship: location_of CCO:B0066155 ! FCN2_HUMAN-Hydroxyproline86 relationship: location_of CCO:B0066160 ! FCN3_HUMAN-Hydroxyproline68 relationship: location_of CCO:B0066172 ! FETUA_HUMAN-Phosphoserine330 relationship: location_of CCO:B0066189 ! FIBA_HUMAN-Phosphoserine364 relationship: location_of CCO:B0066227 ! FMOD_HUMAN-Sulfotyrosine55 relationship: location_of CCO:B0066362 ! GALA_HUMAN-Phosphoserine117 relationship: location_of CCO:B0066385 ! GAST_HUMAN-Sulfotyrosine87 relationship: location_of CCO:B0066471 ! GLUC_HUMAN-Arginine amide127 relationship: location_of CCO:B0066513 ! GON1_HUMAN-Glycine amide33 relationship: location_of CCO:B0066515 ! GON2_HUMAN-Glycine amide33 relationship: location_of CCO:B0066979 ! IAPP_HUMAN-Tyrosine amide70 relationship: location_of CCO:B0066997 ! IBP1_HUMAN-Phosphoserine126 relationship: location_of CCO:B0067079 ! IL4RA_HUMAN-Phosphotyrosine631 relationship: location_of CCO:B0067081 ! IL7RA_HUMAN-Phosphotyrosine169 relationship: location_of CCO:B0067387 ! KNG1_HUMAN-acid19 relationship: location_of CCO:B0067785 ! LRSM1_HUMAN-Phosphoserine604 relationship: location_of CCO:B0068004 ! MATN2_HUMAN-Phosphothreonine895 relationship: location_of CCO:B0068186 ! MIF_HUMAN-Phosphotyrosine37 relationship: location_of CCO:B0068577 ! NEU2_HUMAN-Glycine amide28 relationship: location_of CCO:B0068706 ! NGF_HUMAN-Phosphoserine84 relationship: location_of CCO:B0068754 ! NMS_HUMAN-Asparagine amide141 relationship: location_of CCO:B0068813 ! NPFF_HUMAN-Phenylalanine amide76 relationship: location_of CCO:B0068816 ! NPY_HUMAN-Tyrosine amide64 relationship: location_of CCO:B0068836 ! NRG3_HUMAN-Phosphoserine119 relationship: location_of CCO:B0069000 ! OSTC_HUMAN-4-carboxyglutamate75 relationship: location_of CCO:B0069004 ! OSTN_HUMAN-Arginine amide132 relationship: location_of CCO:B0069208 ! PEDF_HUMAN-Phosphoserine24 relationship: location_of CCO:B0069654 ! PYY_HUMAN-Phosphoserine41 relationship: location_of CCO:B0069901 ! RFRP_HUMAN-Phenylalanine amide131 relationship: location_of CCO:B0070288 ! SAA_HUMAN-N4,N4-dimethylasparagine101 relationship: location_of CCO:B0070346 ! SCG2_HUMAN-Phosphoserine532 relationship: location_of CCO:B0070723 ! SOMA_HUMAN-Phosphoserine176 relationship: location_of CCO:B0071324 ! TEN1_HUMAN-Phosphoserine2580 relationship: location_of CCO:B0071334 ! TENR_HUMAN-Phosphoserine724 relationship: location_of CCO:B0071337 ! TENX_HUMAN-Phosphotyrosine1417 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071393 ! THYG_HUMAN-Triiodothyronine2766 relationship: location_of CCO:B0071536 ! TRFE_HUMAN-Omega-N-methylated arginine42 relationship: location_of CCO:B0071545 ! TRH_HUMAN-Proline amide154 relationship: location_of CCO:B0071632 ! TXLNA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0071661 ! UACA_HUMAN-Phosphotyrosine723 relationship: location_of CCO:B0071711 ! UCN3_HUMAN-Isoleucine amide157 relationship: location_of CCO:B0071810 ! VIP_HUMAN-Methionine amide107 relationship: location_of CCO:B0071946 ! ZA2G_HUMAN-Pyrrolidone carboxylic acid18 [Term] id: CCO:C0000202 name: fibrinogen complex namespace: cellular_component def: "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." [ISBN:0198547684] synonym: "fibrinogen" EXACT [] synonym: "fibrinogen alpha chain" NARROW [] synonym: "fibrinogen beta chain" NARROW [] synonym: "fibrinogen gamma chain" NARROW [] xref: GO:0005577 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0053701 ! A0JLR9_HUMAN relationship: location_of CCO:B0054866 ! FIBB_HUMAN relationship: location_of CCO:B0054867 ! FIBG_HUMAN relationship: location_of CCO:B0055795 ! FGL1_HUMAN relationship: location_of CCO:B0055977 ! FGL2_HUMAN relationship: location_of CCO:B0056259 ! Q3KRA7_HUMAN relationship: location_of CCO:B0056850 ! Q6NSD8_HUMAN relationship: location_of CCO:B0057191 ! Q7Z664_HUMAN relationship: location_of CCO:B0058001 ! Q8WW76_HUMAN relationship: location_of CCO:B0066189 ! FIBA_HUMAN-Phosphoserine364 relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0000203 name: proteinaceous extracellular matrix namespace: cellular_component def: "A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity." [GOC:mtg_sensu, ISBN:0198547684] subset: goslim_generic subset: goslim_goa subset: goslim_plant synonym: "extracellular matrix (sensu Metazoa)" EXACT [] xref: GO:0005578 is_a: CCO:C0001109 ! extracellular matrix relationship: location_of CCO:B0001471 ! TGFB1_HUMAN relationship: location_of CCO:B0001516 ! BMP4_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0001791 ! LTBP2_HUMAN relationship: location_of CCO:B0005949 ! AGRIN_HUMAN relationship: location_of CCO:B0005955 ! FBLN3_HUMAN relationship: location_of CCO:B0005959 ! FBLN1_HUMAN relationship: location_of CCO:B0005964 ! PGBM_HUMAN relationship: location_of CCO:B0005967 ! LAMB1_HUMAN relationship: location_of CCO:B0005989 ! FBLN5_HUMAN relationship: location_of CCO:B0006047 ! WNT16_HUMAN relationship: location_of CCO:B0010556 ! ANXA2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0012658 ! LAMA4_HUMAN-Phosphotyrosine1593 relationship: location_of CCO:B0014612 ! VEGFA_HUMAN-N6-acetyllysine152 relationship: location_of CCO:B0015673 ! CHL1_HUMAN relationship: location_of CCO:B0019689 ! ATS1_HUMAN relationship: location_of CCO:B0019703 ! Q59FE5_HUMAN relationship: location_of CCO:B0020123 ! MFAP4_HUMAN relationship: location_of CCO:B0021696 ! CTGF_HUMAN relationship: location_of CCO:B0024617 ! MMP2_HUMAN relationship: location_of CCO:B0026670 ! TICN1_HUMAN relationship: location_of CCO:B0031878 ! VWF_HUMAN relationship: location_of CCO:B0031949 ! FINC_HUMAN relationship: location_of CCO:B0034581 ! ATS8_HUMAN-Phosphotyrosine255 relationship: location_of CCO:B0035783 ! TICN2_HUMAN-Phosphothreonine86 relationship: location_of CCO:B0038579 ! CBPZ_HUMAN relationship: location_of CCO:B0050218 ! TENA_HUMAN relationship: location_of CCO:B0053803 ! A6NE61_HUMAN relationship: location_of CCO:B0053811 ! A6NF00_HUMAN relationship: location_of CCO:B0053833 ! A6NGS5_HUMAN relationship: location_of CCO:B0053953 ! A8K0G1_HUMAN relationship: location_of CCO:B0054195 ! B0YJ32_HUMAN relationship: location_of CCO:B0054310 ! TR11B_HUMAN relationship: location_of CCO:B0054340 ! WN10B_HUMAN relationship: location_of CCO:B0054341 ! WNT7A_HUMAN relationship: location_of CCO:B0054388 ! WNT9A_HUMAN relationship: location_of CCO:B0054389 ! WNT9B_HUMAN relationship: location_of CCO:B0054418 ! LAMA5_HUMAN relationship: location_of CCO:B0054430 ! CHAD_HUMAN relationship: location_of CCO:B0054464 ! O43266_HUMAN relationship: location_of CCO:B0054617 ! CILP1_HUMAN relationship: location_of CCO:B0054636 ! USH2A_HUMAN relationship: location_of CCO:B0054643 ! GPC4_HUMAN relationship: location_of CCO:B0054777 ! NET1_HUMAN relationship: location_of CCO:B0054822 ! WNT11_HUMAN relationship: location_of CCO:B0054831 ! TIMP1_HUMAN relationship: location_of CCO:B0054891 ! WNT1_HUMAN relationship: location_of CCO:B0054920 ! CO1A2_HUMAN relationship: location_of CCO:B0054944 ! SPRC_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0054985 ! LAMC1_HUMAN relationship: location_of CCO:B0055029 ! MMP9_HUMAN relationship: location_of CCO:B0055046 ! TIMP2_HUMAN relationship: location_of CCO:B0055184 ! LAMA1_HUMAN relationship: location_of CCO:B0055282 ! SFTPD_HUMAN relationship: location_of CCO:B0055297 ! TIMP3_HUMAN relationship: location_of CCO:B0055322 ! COIA1_HUMAN relationship: location_of CCO:B0055336 ! WNT5A_HUMAN relationship: location_of CCO:B0055446 ! MMP14_HUMAN relationship: location_of CCO:B0055548 ! WNT3_HUMAN relationship: location_of CCO:B0055549 ! WNT3A_HUMAN relationship: location_of CCO:B0055550 ! WNT4_HUMAN relationship: location_of CCO:B0055551 ! WNT7B_HUMAN relationship: location_of CCO:B0055647 ! RELN_HUMAN relationship: location_of CCO:B0055782 ! COGA1_HUMAN relationship: location_of CCO:B0055789 ! LG3BP_HUMAN relationship: location_of CCO:B0056020 ! Q14867_HUMAN relationship: location_of CCO:B0056158 ! ECM1_HUMAN relationship: location_of CCO:B0056240 ! P3H1_HUMAN relationship: location_of CCO:B0056271 ! Q3SY79_HUMAN relationship: location_of CCO:B0056327 ! Q4VAJ4_HUMAN relationship: location_of CCO:B0056399 ! Q59G81_HUMAN relationship: location_of CCO:B0056513 ! Q5JYX2_HUMAN relationship: location_of CCO:B0056613 ! Q5TEH8_HUMAN relationship: location_of CCO:B0056656 ! Q5VUM2_HUMAN relationship: location_of CCO:B0056963 ! Q6VU67_HUMAN relationship: location_of CCO:B0056964 ! Q6VU68_HUMAN relationship: location_of CCO:B0057051 ! Q6ZS96_HUMAN relationship: location_of CCO:B0057057 ! Q6ZSP0_HUMAN relationship: location_of CCO:B0057108 ! ATS13_HUMAN relationship: location_of CCO:B0057442 ! Q8N2D3_HUMAN relationship: location_of CCO:B0057449 ! LTBP4_HUMAN relationship: location_of CCO:B0058124 ! WNT2B_HUMAN relationship: location_of CCO:B0058125 ! WNT8B_HUMAN relationship: location_of CCO:B0058572 ! ANGL4_HUMAN relationship: location_of CCO:B0058636 ! WN10A_HUMAN relationship: location_of CCO:B0058665 ! WNT8A_HUMAN relationship: location_of CCO:B0058666 ! WNT5B_HUMAN relationship: location_of CCO:B0059282 ! TENN_HUMAN relationship: location_of CCO:B0059405 ! WNT6_HUMAN relationship: location_of CCO:B0062941 ! NTNG2_HUMAN relationship: location_of CCO:B0063339 ! EMID2_HUMAN relationship: location_of CCO:B0063876 ! BGH3_HUMAN-4-carboxyglutamate131 relationship: location_of CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0064445 ! CO4A3_HUMAN-Phosphoserine1437 relationship: location_of CCO:B0064446 ! CO4A4_HUMAN-Phosphoserine139 relationship: location_of CCO:B0065034 ! ELN_HUMAN-4-hydroxyproline677 relationship: location_of CCO:B0066227 ! FMOD_HUMAN-Sulfotyrosine55 relationship: location_of CCO:B0068004 ! MATN2_HUMAN-Phosphothreonine895 relationship: location_of CCO:B0071334 ! TENR_HUMAN-Phosphoserine724 relationship: location_of CCO:B0071337 ! TENX_HUMAN-Phosphotyrosine1417 [Term] id: CCO:C0000204 name: membrane attack complex namespace: cellular_component def: "A complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow." [GOC:add, ISBN:0198547684, ISBN:068340007X "Stedman's Medical Dictionary", ISBN:0781735149 "Fundamental Immunology"] synonym: "MAC" EXACT [] synonym: "membrane attack complex protein alphaM chain" NARROW [] synonym: "membrane attack complex protein beta2 chain" NARROW [] synonym: "TCC" EXACT [] synonym: "terminal complement complex" EXACT [] xref: GO:0005579 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001978 ! pore complex relationship: location_of CCO:B0054830 ! CO5_HUMAN relationship: location_of CCO:B0054870 ! CO9_HUMAN [Term] id: CCO:C0000205 name: collagen namespace: cellular_component def: "Any of the various assemblies in which collagen chains form a left-handed triple helix; may assemble into higher order structures." [GOC:mah, ISBN:0721639976] synonym: "other collagen" RELATED [] xref: GO:0005581 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0054920 ! CO1A2_HUMAN relationship: location_of CCO:B0055199 ! LYOX_HUMAN relationship: location_of CCO:B0055322 ! COIA1_HUMAN relationship: location_of CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0064445 ! CO4A3_HUMAN-Phosphoserine1437 relationship: location_of CCO:B0064446 ! CO4A4_HUMAN-Phosphoserine139 relationship: part_of CCO:C0000203 ! proteinaceous extracellular matrix [Term] id: CCO:C0000206 name: collagen type XV namespace: cellular_component def: "A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes." [PMID:11158616, PMID:11937714] xref: GO:0005582 is_a: CCO:C0000205 ! collagen [Term] id: CCO:C0000207 name: fibrillar collagen namespace: cellular_component def: "Any collagen polymer in which collagen triple helices associate to form fibrils." [GOC:mah, ISBN:0721639976] xref: GO:0005583 is_a: CCO:C0000205 ! collagen relationship: location_of CCO:B0071337 ! TENX_HUMAN-Phosphotyrosine1417 [Term] id: CCO:C0000208 name: collagen type I namespace: cellular_component def: "A collagen heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; type I collagen triple helices associate to form banded fibrils." [ISBN:0721639976] xref: GO:0005584 is_a: CCO:C0000207 ! fibrillar collagen relationship: location_of CCO:B0054920 ! CO1A2_HUMAN [Term] id: CCO:C0000209 name: collagen type II namespace: cellular_component def: "A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils." [ISBN:0721639976] xref: GO:0005585 is_a: CCO:C0000207 ! fibrillar collagen [Term] id: CCO:C0000210 name: collagen type III namespace: cellular_component def: "A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils." [ISBN:0721639976] xref: GO:0005586 is_a: CCO:C0000207 ! fibrillar collagen relationship: location_of CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 [Term] id: CCO:C0000211 name: collagen type IV namespace: cellular_component def: "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form nets within basement membranes." [ISBN:0721639976] xref: GO:0005587 is_a: CCO:C0001088 ! sheet-forming collagen relationship: location_of CCO:B0064445 ! CO4A3_HUMAN-Phosphoserine1437 relationship: location_of CCO:B0064446 ! CO4A4_HUMAN-Phosphoserine139 relationship: part_of CCO:C0000227 ! basement membrane [Term] id: CCO:C0000212 name: collagen type V namespace: cellular_component def: "A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils." [ISBN:0721639976] xref: GO:0005588 is_a: CCO:C0000207 ! fibrillar collagen [Term] id: CCO:C0000213 name: collagen type VI namespace: cellular_component def: "A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils." [ISBN:0721639976] xref: GO:0005589 is_a: CCO:C0001087 ! anchoring collagen [Term] id: CCO:C0000214 name: collagen type VII namespace: cellular_component def: "A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue." [ISBN:0721639976] xref: GO:0005590 is_a: CCO:C0001087 ! anchoring collagen [Term] id: CCO:C0000215 name: collagen type VIII namespace: cellular_component def: "A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets." [ISBN:0721639976] xref: GO:0005591 is_a: CCO:C0000222 ! short-chain collagen [Term] id: CCO:C0000216 name: collagen type XI namespace: cellular_component def: "A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils." [ISBN:0721639976] xref: GO:0005592 is_a: CCO:C0000207 ! fibrillar collagen [Term] id: CCO:C0000217 name: FACIT collagen namespace: cellular_component def: "Any collagen polymer associated with collagen fibrils and in which the collagen monomers contain two or more relatively short triple-helical domains connected by non-triple-helical sequences; the acronym FACIT stands for fibril-associated collagen with interrupted triple helix." [ISBN:0198599587] xref: GO:0005593 is_a: CCO:C0001087 ! anchoring collagen [Term] id: CCO:C0000218 name: collagen type IX namespace: cellular_component def: "A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils." [ISBN:0721639976] xref: GO:0005594 is_a: CCO:C0000217 ! FACIT collagen [Term] id: CCO:C0000219 name: collagen type XII namespace: cellular_component def: "A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures." [ISBN:0721639976] xref: GO:0005595 is_a: CCO:C0000217 ! FACIT collagen [Term] id: CCO:C0000220 name: collagen type XIV namespace: cellular_component def: "A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures." [ISBN:0721639976] xref: GO:0005596 is_a: CCO:C0000217 ! FACIT collagen [Term] id: CCO:C0000221 name: collagen type XVI namespace: cellular_component def: "A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils." [GOC:mah, PMID:12782140] xref: GO:0005597 is_a: CCO:C0000217 ! FACIT collagen relationship: location_of CCO:B0055782 ! COGA1_HUMAN [Term] id: CCO:C0000222 name: short-chain collagen namespace: cellular_component def: "Any assembly of collagen in which the collagen chains are relatively short compared to the fibrillar collagens." [ISBN:0198599587] xref: GO:0005598 is_a: CCO:C0001088 ! sheet-forming collagen [Term] id: CCO:C0000223 name: collagen type X namespace: cellular_component def: "A collagen homotrimer of alpha1(X) chains; type X collagen triple helices may form nets." [ISBN:0721639976] xref: GO:0005599 is_a: CCO:C0000222 ! short-chain collagen [Term] id: CCO:C0000224 name: collagen type XIII namespace: cellular_component def: "A collagen homotrimer of alpha1(XIII) chains; type X collagen triple helices span lipid bilayer membranes." [ISBN:0721639976] xref: GO:0005600 is_a: CCO:C0001089 ! transmembrane collagen [Term] id: CCO:C0000225 name: classical-complement-pathway C3/C5 convertase complex namespace: cellular_component def: "A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone." [BRENDA:3.4.21.43, GOC:mah, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/Complement.html] xref: GO:0005601 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0000226 name: complement component C1 complex namespace: cellular_component def: "A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "complement component C1q complex" NARROW [] xref: GO:0005602 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0000227 name: basement membrane namespace: cellular_component def: "A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." [ISBN:0198547684] xref: GO:0005604 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0002059 ! LAP2_HUMAN relationship: location_of CCO:B0005215 ! FBLN4_HUMAN relationship: location_of CCO:B0005964 ! PGBM_HUMAN relationship: location_of CCO:B0005967 ! LAMB1_HUMAN relationship: location_of CCO:B0006179 ! APLP1_HUMAN relationship: location_of CCO:B0010556 ! ANXA2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0012658 ! LAMA4_HUMAN-Phosphotyrosine1593 relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: location_of CCO:B0034592 ! BPA1_HUMAN-Phosphothreonine224 relationship: location_of CCO:B0050218 ! TENA_HUMAN relationship: location_of CCO:B0053811 ! A6NF00_HUMAN relationship: location_of CCO:B0054195 ! B0YJ32_HUMAN relationship: location_of CCO:B0054196 ! B0YJ33_HUMAN relationship: location_of CCO:B0054418 ! LAMA5_HUMAN relationship: location_of CCO:B0054636 ! USH2A_HUMAN relationship: location_of CCO:B0054944 ! SPRC_HUMAN relationship: location_of CCO:B0054985 ! LAMC1_HUMAN relationship: location_of CCO:B0055046 ! TIMP2_HUMAN relationship: location_of CCO:B0055047 ! LEUK_HUMAN relationship: location_of CCO:B0055184 ! LAMA1_HUMAN relationship: location_of CCO:B0056656 ! Q5VUM2_HUMAN relationship: location_of CCO:B0056963 ! Q6VU67_HUMAN relationship: location_of CCO:B0056964 ! Q6VU68_HUMAN relationship: location_of CCO:B0056965 ! Q6VU69_HUMAN relationship: location_of CCO:B0064445 ! CO4A3_HUMAN-Phosphoserine1437 relationship: location_of CCO:B0064446 ! CO4A4_HUMAN-Phosphoserine139 relationship: part_of CCO:C0000203 ! proteinaceous extracellular matrix [Term] id: CCO:C0000228 name: basal lamina namespace: cellular_component def: "A thin sheet of proteoglycans and glycoproteins, especially laminin, secreted by cells as an extracellular matrix." [ISBN:0198547684] synonym: "basement lamina" EXACT [] xref: GO:0005605 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0005949 ! AGRIN_HUMAN relationship: location_of CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 relationship: location_of CCO:B0012658 ! LAMA4_HUMAN-Phosphotyrosine1593 relationship: location_of CCO:B0054985 ! LAMC1_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: part_of CCO:C0000227 ! basement membrane [Term] id: CCO:C0000229 name: laminin-1 complex namespace: cellular_component def: "A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0005606 is_a: CCO:C0001756 ! laminin complex relationship: location_of CCO:B0005967 ! LAMB1_HUMAN relationship: location_of CCO:B0012658 ! LAMA4_HUMAN-Phosphotyrosine1593 relationship: location_of CCO:B0053811 ! A6NF00_HUMAN relationship: location_of CCO:B0053833 ! A6NGS5_HUMAN relationship: location_of CCO:B0054195 ! B0YJ32_HUMAN relationship: location_of CCO:B0054196 ! B0YJ33_HUMAN relationship: location_of CCO:B0054418 ! LAMA5_HUMAN relationship: location_of CCO:B0054985 ! LAMC1_HUMAN relationship: location_of CCO:B0055184 ! LAMA1_HUMAN relationship: location_of CCO:B0056431 ! Q5H8W3_HUMAN relationship: location_of CCO:B0056656 ! Q5VUM2_HUMAN relationship: location_of CCO:B0056963 ! Q6VU67_HUMAN relationship: location_of CCO:B0056964 ! Q6VU68_HUMAN relationship: location_of CCO:B0056965 ! Q6VU69_HUMAN [Term] id: CCO:C0000230 name: laminin-2 complex namespace: cellular_component def: "A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0005607 is_a: CCO:C0001756 ! laminin complex is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005967 ! LAMB1_HUMAN [Term] id: CCO:C0000231 name: laminin-3 complex namespace: cellular_component def: "A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains." [MEDLINE:95005761] xref: GO:0005608 is_a: CCO:C0001756 ! laminin complex relationship: location_of CCO:B0055184 ! LAMA1_HUMAN [Term] id: CCO:C0000232 name: laminin-4 complex namespace: cellular_component def: "A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0005609 is_a: CCO:C0001756 ! laminin complex [Term] id: CCO:C0000233 name: laminin-5 complex namespace: cellular_component def: "A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0005610 is_a: CCO:C0001756 ! laminin complex [Term] id: CCO:C0000234 name: laminin-6 complex namespace: cellular_component def: "A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0005611 is_a: CCO:C0001756 ! laminin complex [Term] id: CCO:C0000235 name: laminin-7 complex namespace: cellular_component def: "A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0005612 is_a: CCO:C0001756 ! laminin complex [Term] id: CCO:C0000236 name: interstitial matrix namespace: cellular_component def: "A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens." [PMID:8450001] xref: GO:0005614 is_a: CCO:C0000203 ! proteinaceous extracellular matrix [Term] id: CCO:C0000237 name: extracellular space namespace: cellular_component def: "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] comment: Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. subset: goslim_generic subset: goslim_goa subset: goslim_plant synonym: "intercellular space" RELATED [] xref: GO:0005615 is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0001362 ! EREG_HUMAN relationship: location_of CCO:B0001379 ! FGF10_HUMAN relationship: location_of CCO:B0001402 ! VEGFD_HUMAN relationship: location_of CCO:B0001448 ! TNF15_HUMAN relationship: location_of CCO:B0001470 ! EGF_HUMAN relationship: location_of CCO:B0001471 ! TGFB1_HUMAN relationship: location_of CCO:B0001473 ! TNFB_HUMAN relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0001475 ! IL1A_HUMAN relationship: location_of CCO:B0001476 ! IL1B_HUMAN relationship: location_of CCO:B0001480 ! PDGFA_HUMAN relationship: location_of CCO:B0001484 ! IFNW1_HUMAN relationship: location_of CCO:B0001502 ! FGF2_HUMAN relationship: location_of CCO:B0001504 ! IL8_HUMAN relationship: location_of CCO:B0001514 ! FGF5_HUMAN relationship: location_of CCO:B0001515 ! BMP2_HUMAN relationship: location_of CCO:B0001516 ! BMP4_HUMAN relationship: location_of CCO:B0001531 ! BMP7_HUMAN relationship: location_of CCO:B0001541 ! PTN_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0001583 ! FGF9_HUMAN relationship: location_of CCO:B0001947 ! EGFL6_HUMAN relationship: location_of CCO:B0005205 ! IL1F5_HUMAN relationship: location_of CCO:B0005328 ! NOGG_HUMAN relationship: location_of CCO:B0005450 ! ICAM1_HUMAN relationship: location_of CCO:B0005618 ! TRBM_HUMAN relationship: location_of CCO:B0005646 ! FGFP1_HUMAN relationship: location_of CCO:B0005959 ! FBLN1_HUMAN relationship: location_of CCO:B0005961 ! GRN_HUMAN relationship: location_of CCO:B0006087 ! CCL18_HUMAN relationship: location_of CCO:B0006141 ! FXYD6_HUMAN relationship: location_of CCO:B0006180 ! GDF9_HUMAN relationship: location_of CCO:B0006193 ! VTDB_HUMAN relationship: location_of CCO:B0006239 ! RED_HUMAN relationship: location_of CCO:B0006308 ! WFDC2_HUMAN relationship: location_of CCO:B0010371 ! 1433S_HUMAN-Phosphoserine216 relationship: location_of CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0014355 ! THRB_HUMAN-4-carboxyglutamate59 relationship: location_of CCO:B0014388 ! TKNK_HUMAN-Methionine amide90 relationship: location_of CCO:B0014612 ! VEGFA_HUMAN-N6-acetyllysine152 relationship: location_of CCO:B0014615 ! VGFR1_HUMAN-Phosphotyrosine1213 relationship: location_of CCO:B0015956 ! IFNK_HUMAN relationship: location_of CCO:B0015966 ! IFNB_HUMAN relationship: location_of CCO:B0015973 ! IFNA2_HUMAN relationship: location_of CCO:B0017511 ! FGF22_HUMAN relationship: location_of CCO:B0017668 ! FGF12_HUMAN relationship: location_of CCO:B0017671 ! FGF16_HUMAN relationship: location_of CCO:B0021671 ! HBEGF_HUMAN relationship: location_of CCO:B0022985 ! FGF17_HUMAN relationship: location_of CCO:B0022986 ! FGF18_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0024369 ! IL7_HUMAN relationship: location_of CCO:B0024617 ! MMP2_HUMAN relationship: location_of CCO:B0027467 ! MCA1_HUMAN relationship: location_of CCO:B0028166 ! A1AT_HUMAN relationship: location_of CCO:B0030742 ! IDE_HUMAN relationship: location_of CCO:B0031669 ! RSPO1_HUMAN relationship: location_of CCO:B0031813 ! IFNG_HUMAN relationship: location_of CCO:B0032938 ! ANGT_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0033567 ! GHRL_HUMAN relationship: location_of CCO:B0035358 ! PECA1_HUMAN-Phosphotyrosine713 relationship: location_of CCO:B0035955 ! CXCL7_HUMAN relationship: location_of CCO:B0038878 ! CSF1_HUMAN relationship: location_of CCO:B0038963 ! CCL7_HUMAN relationship: location_of CCO:B0038969 ! CCL11_HUMAN relationship: location_of CCO:B0039348 ! CCL13_HUMAN-acid24 relationship: location_of CCO:B0039349 ! CCL2_HUMAN-Pyrrolidone carboxylic acid24 relationship: location_of CCO:B0039351 ! CCL8_HUMAN-Pyrrolidone carboxylic acid24 relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039671 ! TCTP_HUMAN-Phosphoserine46 relationship: location_of CCO:B0039858 ! KLK8_HUMAN relationship: location_of CCO:B0041664 ! PLF4_HUMAN relationship: location_of CCO:B0041666 ! CXCL5_HUMAN relationship: location_of CCO:B0041668 ! GROA_HUMAN relationship: location_of CCO:B0041670 ! CXCL6_HUMAN relationship: location_of CCO:B0042116 ! GDF5_HUMAN relationship: location_of CCO:B0042120 ! NODAL_HUMAN relationship: location_of CCO:B0042127 ! BMP10_HUMAN relationship: location_of CCO:B0042130 ! BMP6_HUMAN relationship: location_of CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 relationship: location_of CCO:B0043821 ! IGF1B_HUMAN relationship: location_of CCO:B0043822 ! EDN1_HUMAN relationship: location_of CCO:B0043824 ! IL12B_HUMAN relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0048872 ! ALS_HUMAN relationship: location_of CCO:B0049672 ! TPO_HUMAN relationship: location_of CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0054295 ! CCL24_HUMAN relationship: location_of CCO:B0054308 ! LFTY2_HUMAN relationship: location_of CCO:B0054334 ! CCL21_HUMAN relationship: location_of CCO:B0054338 ! CCL22_HUMAN relationship: location_of CCO:B0054359 ! CXL11_HUMAN relationship: location_of CCO:B0054375 ! TNF11_HUMAN relationship: location_of CCO:B0054376 ! GDF8_HUMAN relationship: location_of CCO:B0054408 ! ANGP2_HUMAN relationship: location_of CCO:B0054410 ! MYT2_HUMAN relationship: location_of CCO:B0054436 ! CCL25_HUMAN relationship: location_of CCO:B0054484 ! TNF12_HUMAN relationship: location_of CCO:B0054490 ! TNF14_HUMAN relationship: location_of CCO:B0054617 ! CILP1_HUMAN relationship: location_of CCO:B0054657 ! LFTY1_HUMAN relationship: location_of CCO:B0054674 ! TNF13_HUMAN relationship: location_of CCO:B0054756 ! GDF11_HUMAN relationship: location_of CCO:B0054778 ! FSTL3_HUMAN relationship: location_of CCO:B0054795 ! CER1_HUMAN relationship: location_of CCO:B0054799 ! ANGL1_HUMAN relationship: location_of CCO:B0054825 ! LALBA_HUMAN relationship: location_of CCO:B0054826 ! PLMN_HUMAN relationship: location_of CCO:B0054828 ! RENI_HUMAN relationship: location_of CCO:B0054830 ! CO5_HUMAN relationship: location_of CCO:B0054845 ! CALC_HUMAN relationship: location_of CCO:B0054852 ! INS_HUMAN relationship: location_of CCO:B0054855 ! EPO_HUMAN relationship: location_of CCO:B0054863 ! APOA2_HUMAN relationship: location_of CCO:B0054864 ! APOC3_HUMAN relationship: location_of CCO:B0054871 ! APOH_HUMAN relationship: location_of CCO:B0054874 ! ALBU_HUMAN relationship: location_of CCO:B0054875 ! CXL10_HUMAN relationship: location_of CCO:B0054883 ! PA21B_HUMAN relationship: location_of CCO:B0054884 ! PROC_HUMAN relationship: location_of CCO:B0054885 ! CSF2_HUMAN relationship: location_of CCO:B0054894 ! IL4_HUMAN relationship: location_of CCO:B0054895 ! IL5_HUMAN relationship: location_of CCO:B0054899 ! IL6_HUMAN relationship: location_of CCO:B0054907 ! CALCA_HUMAN relationship: location_of CCO:B0054913 ! GRP_HUMAN relationship: location_of CCO:B0054931 ! IL3_HUMAN relationship: location_of CCO:B0054942 ! LEG1_HUMAN relationship: location_of CCO:B0054952 ! CSF3_HUMAN relationship: location_of CCO:B0054972 ! CCL3_HUMAN relationship: location_of CCO:B0054980 ! CLUS_HUMAN relationship: location_of CCO:B0054999 ! PTHR_HUMAN relationship: location_of CCO:B0055006 ! ACE_HUMAN relationship: location_of CCO:B0055011 ! CCL4_HUMAN relationship: location_of CCO:B0055013 ! CCL5_HUMAN relationship: location_of CCO:B0055018 ! ONCM_HUMAN relationship: location_of CCO:B0055029 ! MMP9_HUMAN relationship: location_of CCO:B0055030 ! LIF_HUMAN relationship: location_of CCO:B0055032 ! IL9_HUMAN relationship: location_of CCO:B0055039 ! AREG_HUMAN relationship: location_of CCO:B0055047 ! LEUK_HUMAN relationship: location_of CCO:B0055058 ! CL3L1_HUMAN relationship: location_of CCO:B0055059 ! ANFB_HUMAN relationship: location_of CCO:B0055094 ! IBP3_HUMAN relationship: location_of CCO:B0055098 ! IBP2_HUMAN relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0055119 ! TKN1_HUMAN relationship: location_of CCO:B0055126 ! IL11_HUMAN relationship: location_of CCO:B0055142 ! IL10_HUMAN relationship: location_of CCO:B0055144 ! CCL1_HUMAN relationship: location_of CCO:B0055145 ! ENPP1_HUMAN relationship: location_of CCO:B0055160 ! TNFL4_HUMAN relationship: location_of CCO:B0055170 ! CRHBP_HUMAN relationship: location_of CCO:B0055262 ! CD70_HUMAN relationship: location_of CCO:B0055263 ! TNFL8_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055333 ! LEP_HUMAN relationship: location_of CCO:B0055336 ! WNT5A_HUMAN relationship: location_of CCO:B0055340 ! TNFL9_HUMAN relationship: location_of CCO:B0055347 ! ASIP_HUMAN relationship: location_of CCO:B0055397 ! XCL1_HUMAN relationship: location_of CCO:B0055398 ! TNFL6_HUMAN relationship: location_of CCO:B0055399 ! SDF1_HUMAN relationship: location_of CCO:B0055435 ! FLT3L_HUMAN relationship: location_of CCO:B0055455 ! TNF10_HUMAN relationship: location_of CCO:B0055502 ! STC1_HUMAN relationship: location_of CCO:B0055528 ! BMP3B_HUMAN relationship: location_of CCO:B0055534 ! CAD13_HUMAN relationship: location_of CCO:B0055537 ! CCL23_HUMAN relationship: location_of CCO:B0055549 ! WNT3A_HUMAN relationship: location_of CCO:B0055607 ! SMS_HUMAN relationship: location_of CCO:B0055645 ! X3CL1_HUMAN relationship: location_of CCO:B0055653 ! CCL20_HUMAN relationship: location_of CCO:B0055681 ! NDP_HUMAN relationship: location_of CCO:B0055686 ! IL9R_HUMAN relationship: location_of CCO:B0055688 ! IL5RA_HUMAN relationship: location_of CCO:B0055766 ! REG3A_HUMAN relationship: location_of CCO:B0055770 ! TNFC_HUMAN relationship: location_of CCO:B0055783 ! CXCL9_HUMAN relationship: location_of CCO:B0055789 ! LG3BP_HUMAN relationship: location_of CCO:B0055848 ! FSTL1_HUMAN relationship: location_of CCO:B0055957 ! IL18_HUMAN relationship: location_of CCO:B0055972 ! IL27B_HUMAN relationship: location_of CCO:B0056004 ! IHH_HUMAN relationship: location_of CCO:B0056006 ! INSL4_HUMAN relationship: location_of CCO:B0056066 ! SHH_HUMAN relationship: location_of CCO:B0056152 ! CART_HUMAN relationship: location_of CCO:B0056160 ! CTF1_HUMAN relationship: location_of CCO:B0056164 ! CCL14_HUMAN relationship: location_of CCO:B0056171 ! CCL15_HUMAN relationship: location_of CCO:B0056175 ! MIA_HUMAN relationship: location_of CCO:B0056226 ! VWC2_HUMAN relationship: location_of CCO:B0056575 ! SFRP5_HUMAN relationship: location_of CCO:B0056733 ! SFRP4_HUMAN relationship: location_of CCO:B0056834 ! GDF6_HUMAN relationship: location_of CCO:B0057317 ! IL29_HUMAN relationship: location_of CCO:B0057464 ! SFRP1_HUMAN relationship: location_of CCO:B0057558 ! PCSK9_HUMAN relationship: location_of CCO:B0057596 ! IL27A_HUMAN relationship: location_of CCO:B0057996 ! SCTM1_HUMAN relationship: location_of CCO:B0058067 ! CCL17_HUMAN relationship: location_of CCO:B0058087 ! HTRA1_HUMAN relationship: location_of CCO:B0058124 ! WNT2B_HUMAN relationship: location_of CCO:B0058134 ! I22R2_HUMAN relationship: location_of CCO:B0058356 ! SG3A1_HUMAN relationship: location_of CCO:B0058448 ! CCL19_HUMAN relationship: location_of CCO:B0058466 ! GDF15_HUMAN relationship: location_of CCO:B0058578 ! ACE2_HUMAN relationship: location_of CCO:B0058640 ! FGF23_HUMAN relationship: location_of CCO:B0058642 ! IL22_HUMAN relationship: location_of CCO:B0058643 ! TWSG1_HUMAN relationship: location_of CCO:B0058739 ! GREM2_HUMAN relationship: location_of CCO:B0058783 ! IL21_HUMAN relationship: location_of CCO:B0058798 ! WFDC1_HUMAN relationship: location_of CCO:B0058902 ! CYTL1_HUMAN relationship: location_of CCO:B0058987 ! IL20_HUMAN relationship: location_of CCO:B0059031 ! IL17C_HUMAN relationship: location_of CCO:B0059068 ! XCL2_HUMAN relationship: location_of CCO:B0059069 ! CLCF1_HUMAN relationship: location_of CCO:B0059080 ! DKK3_HUMAN relationship: location_of CCO:B0059082 ! CKLF_HUMAN relationship: location_of CCO:B0059085 ! DKK2_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059136 ! IL19_HUMAN relationship: location_of CCO:B0059139 ! PCSK1_HUMAN relationship: location_of CCO:B0059181 ! GDF2_HUMAN relationship: location_of CCO:B0059204 ! ANGL2_HUMAN relationship: location_of CCO:B0059292 ! CCL26_HUMAN relationship: location_of CCO:B0059296 ! TN13B_HUMAN relationship: location_of CCO:B0059334 ! UTP11_HUMAN relationship: location_of CCO:B0059377 ! ANGL3_HUMAN relationship: location_of CCO:B0062887 ! CETP_HUMAN relationship: location_of CCO:B0062974 ! BMP1_HUMAN relationship: location_of CCO:B0063047 ! LYSC_HUMAN relationship: location_of CCO:B0063118 ! LEG7_HUMAN relationship: location_of CCO:B0063191 ! GREM1_HUMAN relationship: location_of CCO:B0063227 ! MEP1B_HUMAN relationship: location_of CCO:B0063254 ! IL33_HUMAN relationship: location_of CCO:B0063255 ! CN37_HUMAN relationship: location_of CCO:B0063292 ! SAP_HUMAN relationship: location_of CCO:B0063294 ! IL1RA_HUMAN relationship: location_of CCO:B0063374 ! TTHY_HUMAN relationship: location_of CCO:B0063876 ! BGH3_HUMAN-4-carboxyglutamate131 relationship: location_of CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0065416 ! ADIPO_HUMAN-5-hydroxylysine65 relationship: location_of CCO:B0065425 ! ADML_HUMAN-Tyrosine amide146 relationship: location_of CCO:B0066160 ! FCN3_HUMAN-Hydroxyproline68 relationship: location_of CCO:B0066172 ! FETUA_HUMAN-Phosphoserine330 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0066498 ! GNL1_HUMAN-Phosphoserine68 relationship: location_of CCO:B0066784 ! HDGF_HUMAN-Phosphoserine199 relationship: location_of CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0066997 ! IBP1_HUMAN-Phosphoserine126 relationship: location_of CCO:B0068186 ! MIF_HUMAN-Phosphotyrosine37 relationship: location_of CCO:B0068816 ! NPY_HUMAN-Tyrosine amide64 relationship: location_of CCO:B0069004 ! OSTN_HUMAN-Arginine amide132 relationship: location_of CCO:B0070346 ! SCG2_HUMAN-Phosphoserine532 relationship: location_of CCO:B0071536 ! TRFE_HUMAN-Omega-N-methylated arginine42 [Term] id: CCO:C0000238 name: larval serum protein complex namespace: cellular_component def: "A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins." [GOC:jl, UniProtKB:P11995] xref: GO:0005616 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0000239 name: cell wall namespace: cellular_component def: "The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan." [ISBN:0198547684] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0005618 is_a: CCO:C0000999 ! external encapsulating structure [Term] id: CCO:C0000241 name: cellular bud scar namespace: cellular_component def: "Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age." [GOC:rn, PMID:14600225, PMID:2005820] xref: GO:0005621 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0002066 ! fungal-type cell wall [Term] id: CCO:C0000242 name: intracellular namespace: cellular_component def: "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: gosubset_prok synonym: "protoplasm" EXACT [] xref: GO:0005622 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0001358 ! OVOL1_HUMAN relationship: location_of CCO:B0001366 ! MDM4_HUMAN relationship: location_of CCO:B0001367 ! AXN1_HUMAN relationship: location_of CCO:B0001371 ! LX15B_HUMAN relationship: location_of CCO:B0001393 ! O43550_HUMAN relationship: location_of CCO:B0001408 ! EVI5_HUMAN relationship: location_of CCO:B0001416 ! TRI13_HUMAN relationship: location_of CCO:B0001433 ! TAD3L_HUMAN relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0001466 ! RASN_HUMAN relationship: location_of CCO:B0001520 ! ERF3A_HUMAN relationship: location_of CCO:B0001536 ! WT1_HUMAN relationship: location_of CCO:B0001577 ! MPIP2_HUMAN relationship: location_of CCO:B0001598 ! BRCA1_HUMAN relationship: location_of CCO:B0001603 ! BCL6_HUMAN relationship: location_of CCO:B0001630 ! CTCF_HUMAN relationship: location_of CCO:B0001691 ! RS4X_HUMAN relationship: location_of CCO:B0001692 ! RHOB_HUMAN relationship: location_of CCO:B0001712 ! MDM2_HUMAN relationship: location_of CCO:B0001721 ! RAD51_HUMAN relationship: location_of CCO:B0001741 ! ZBT17_HUMAN relationship: location_of CCO:B0001770 ! NFYC_HUMAN relationship: location_of CCO:B0001783 ! HIC1_HUMAN relationship: location_of CCO:B0001784 ! DMC1_HUMAN relationship: location_of CCO:B0001875 ! HECD3_HUMAN relationship: location_of CCO:B0001899 ! DAB2P_HUMAN relationship: location_of CCO:B0001923 ! Q6ZNA8_HUMAN relationship: location_of CCO:B0001954 ! XRN1_HUMAN relationship: location_of CCO:B0002023 ! ARHG1_HUMAN relationship: location_of CCO:B0002033 ! PINX1_HUMAN relationship: location_of CCO:B0002039 ! SIPA1_HUMAN relationship: location_of CCO:B0002042 ! SGSM3_HUMAN relationship: location_of CCO:B0002083 ! GFI1_HUMAN relationship: location_of CCO:B0002086 ! BARD1_HUMAN relationship: location_of CCO:B0002103 ! GNL3_HUMAN relationship: location_of CCO:B0002127 ! Q9H2F0_HUMAN relationship: location_of CCO:B0002153 ! CYLD_HUMAN relationship: location_of CCO:B0002188 ! RHG20_HUMAN relationship: location_of CCO:B0002205 ! MUTYH_HUMAN relationship: location_of CCO:B0002206 ! HERC5_HUMAN relationship: location_of CCO:B0002228 ! ASC_HUMAN relationship: location_of CCO:B0002231 ! PLAL1_HUMAN relationship: location_of CCO:B0002253 ! STA13_HUMAN relationship: location_of CCO:B0002254 ! RBGP1_HUMAN relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005201 ! GLIS3_HUMAN relationship: location_of CCO:B0005211 ! DVL2_HUMAN relationship: location_of CCO:B0005213 ! IKZF1_HUMAN relationship: location_of CCO:B0005214 ! ZN581_HUMAN relationship: location_of CCO:B0005216 ! RIPK2_HUMAN relationship: location_of CCO:B0005228 ! ZN580_HUMAN relationship: location_of CCO:B0005230 ! Q8IVD8_HUMAN relationship: location_of CCO:B0005263 ! ZN567_HUMAN relationship: location_of CCO:B0005276 ! ZN764_HUMAN relationship: location_of CCO:B0005279 ! TBC17_HUMAN relationship: location_of CCO:B0005297 ! ZN263_HUMAN relationship: location_of CCO:B0005301 ! MAF1_HUMAN relationship: location_of CCO:B0005308 ! ZN451_HUMAN relationship: location_of CCO:B0005322 ! SMAD4_HUMAN relationship: location_of CCO:B0005338 ! CDC42_HUMAN relationship: location_of CCO:B0005348 ! EXOSX_HUMAN relationship: location_of CCO:B0005364 ! RUVB2_HUMAN relationship: location_of CCO:B0005382 ! NFYB_HUMAN relationship: location_of CCO:B0005417 ! SMRC2_HUMAN relationship: location_of CCO:B0005418 ! SMRC1_HUMAN relationship: location_of CCO:B0005467 ! PARP1_HUMAN relationship: location_of CCO:B0005483 ! STAU1_HUMAN relationship: location_of CCO:B0005485 ! SP1_HUMAN relationship: location_of CCO:B0005497 ! ARID2_HUMAN relationship: location_of CCO:B0005541 ! UCHL1_HUMAN relationship: location_of CCO:B0005547 ! PLXB3_HUMAN relationship: location_of CCO:B0005550 ! RGL1_HUMAN relationship: location_of CCO:B0005552 ! NCOA7_HUMAN relationship: location_of CCO:B0005564 ! RHG18_HUMAN relationship: location_of CCO:B0005578 ! ZN655_HUMAN relationship: location_of CCO:B0005593 ! CRNL1_HUMAN relationship: location_of CCO:B0005644 ! Q9BWP7_HUMAN relationship: location_of CCO:B0005645 ! OBSCN_HUMAN relationship: location_of CCO:B0005666 ! SOS2_HUMAN relationship: location_of CCO:B0005671 ! BIRC2_HUMAN relationship: location_of CCO:B0005693 ! ARI4A_HUMAN relationship: location_of CCO:B0005744 ! RS19_HUMAN relationship: location_of CCO:B0005746 ! RL7_HUMAN relationship: location_of CCO:B0005750 ! RS9_HUMAN relationship: location_of CCO:B0005751 ! RL22_HUMAN relationship: location_of CCO:B0005761 ! RL7A_HUMAN relationship: location_of CCO:B0005767 ! RS12_HUMAN relationship: location_of CCO:B0005768 ! RS3A_HUMAN relationship: location_of CCO:B0005776 ! RSSA_HUMAN relationship: location_of CCO:B0005850 ! GLI3_HUMAN relationship: location_of CCO:B0005851 ! DIRA2_HUMAN relationship: location_of CCO:B0005855 ! RL12_HUMAN relationship: location_of CCO:B0005857 ! RL15_HUMAN relationship: location_of CCO:B0005858 ! RL11_HUMAN relationship: location_of CCO:B0005859 ! RL27_HUMAN relationship: location_of CCO:B0005860 ! RL8_HUMAN relationship: location_of CCO:B0005861 ! RL4_HUMAN relationship: location_of CCO:B0005885 ! DPOE3_HUMAN relationship: location_of CCO:B0005912 ! GNDS_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0005943 ! APTX_HUMAN relationship: location_of CCO:B0005952 ! CT012_HUMAN relationship: location_of CCO:B0005962 ! HECW1_HUMAN relationship: location_of CCO:B0005969 ! TRIM1_HUMAN relationship: location_of CCO:B0005981 ! TRI27_HUMAN relationship: location_of CCO:B0005982 ! RNF31_HUMAN relationship: location_of CCO:B0006009 ! OSBL1_HUMAN relationship: location_of CCO:B0006014 ! ZN443_HUMAN relationship: location_of CCO:B0006020 ! BC11A_HUMAN relationship: location_of CCO:B0006038 ! NKRF_HUMAN relationship: location_of CCO:B0006040 ! OLA1_HUMAN relationship: location_of CCO:B0006050 ! UTP6_HUMAN relationship: location_of CCO:B0006067 ! NTF2_HUMAN relationship: location_of CCO:B0006070 ! EGR2_HUMAN relationship: location_of CCO:B0006095 ! RT12_HUMAN relationship: location_of CCO:B0006107 ! SAT1_HUMAN relationship: location_of CCO:B0006117 ! AK1C3_HUMAN relationship: location_of CCO:B0006120 ! ARL3_HUMAN relationship: location_of CCO:B0006182 ! CRADD_HUMAN relationship: location_of CCO:B0006186 ! DUS12_HUMAN relationship: location_of CCO:B0006208 ! RT06_HUMAN relationship: location_of CCO:B0006229 ! RIT1_HUMAN relationship: location_of CCO:B0006231 ! RL37A_HUMAN relationship: location_of CCO:B0006248 ! RM20_HUMAN relationship: location_of CCO:B0006254 ! ZNF7_HUMAN relationship: location_of CCO:B0006256 ! ARL4D_HUMAN relationship: location_of CCO:B0006284 ! MKKS_HUMAN relationship: location_of CCO:B0006292 ! PLXB2_HUMAN relationship: location_of CCO:B0006322 ! CYTA_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: location_of CCO:B0006345 ! CATB_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010485 ! AKAP8_HUMAN-Phosphoserine339 relationship: location_of CCO:B0010535 ! ANKZ1_HUMAN-Phosphoserine398 relationship: location_of CCO:B0010588 ! ARD1A_HUMAN-Phosphoserine186 relationship: location_of CCO:B0010600 ! ARI1A_HUMAN-Phosphoserine1755 relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010643 ! ATF7_HUMAN-Phosphothreonine51 relationship: location_of CCO:B0010721 ! ATX7_HUMAN-Phosphothreonine854 relationship: location_of CCO:B0010767 ! BCAR3_HUMAN-Phosphoserine370 relationship: location_of CCO:B0010779 ! BCR_HUMAN-Phosphothreonine310 relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 relationship: location_of CCO:B0011182 ! CETN2_HUMAN-Phosphothreonine26 relationship: location_of CCO:B0011509 ! DHX9_HUMAN-Phosphotyrosine1241 relationship: location_of CCO:B0011527 ! DLG5_HUMAN-Phosphothreonine1011 relationship: location_of CCO:B0011579 ! DPOE4_HUMAN-Phosphoserine25 relationship: location_of CCO:B0011612 ! E2AK2_HUMAN-Phosphothreonine88 relationship: location_of CCO:B0011648 ! EF1G_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011798 ! EWS_HUMAN-Asymmetric dimethylarginine589 relationship: location_of CCO:B0011896 ! FRK_HUMAN-Phosphotyrosine387 relationship: location_of CCO:B0011921 ! GBF1_HUMAN-Phosphoserine1773 relationship: location_of CCO:B0011929 ! GFI1B_HUMAN-Phosphoserine261 relationship: location_of CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0011943 ! GLU2B_HUMAN-Phosphoserine383 relationship: location_of CCO:B0012288 ! HUWE1_HUMAN-Phosphoserine1907 relationship: location_of CCO:B0012366 ! ILF3_HUMAN-Phosphoserine62 relationship: location_of CCO:B0012432 ! ITSN2_HUMAN-Phosphotyrosine967 relationship: location_of CCO:B0012863 ! MDC1_HUMAN-Phosphothreonine523 relationship: location_of CCO:B0012984 ! MPIP1_HUMAN-Phosphoserine124 relationship: location_of CCO:B0013079 ! MYST2_HUMAN-Phosphothreonine88 relationship: location_of CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0013549 ! PKN1_HUMAN-Phosphothreonine774 relationship: location_of CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: location_of CCO:B0013659 ! RAC1_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0013709 ! RAP1A_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0013714 ! RASA1_HUMAN-Phosphotyrosine615 relationship: location_of CCO:B0013716 ! RASK_HUMAN-ester186 relationship: location_of CCO:B0013792 ! RBM5_HUMAN-Phosphoserine624 relationship: location_of CCO:B0013831 ! RFC1_HUMAN-Phosphothreonine110 relationship: location_of CCO:B0013859 ! RHOG_HUMAN-Cysteine methyl ester188 relationship: location_of CCO:B0013882 ! RL12_HUMAN-Phosphoserine38 relationship: location_of CCO:B0013884 ! RL18A_HUMAN-Phosphotyrosine63 relationship: location_of CCO:B0013886 ! RL18_HUMAN-Phosphoserine130 relationship: location_of CCO:B0013888 ! RL24_HUMAN-Phosphoserine86 relationship: location_of CCO:B0013889 ! RL28_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013896 ! RLA0_HUMAN-Phosphotyrosine24 relationship: location_of CCO:B0013900 ! RLA1_HUMAN-Phosphotyrosine11 relationship: location_of CCO:B0013905 ! RLA2_HUMAN-Phosphoserine102 relationship: location_of CCO:B0013908 ! RNC_HUMAN-Phosphoserine284 relationship: location_of CCO:B0013936 ! RS13_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013939 ! RS20_HUMAN-Phosphothreonine9 relationship: location_of CCO:B0013940 ! RS24_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013943 ! RS7_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013988 ! SENP7_HUMAN-Phosphoserine377 relationship: location_of CCO:B0014264 ! STMN1_HUMAN-Phosphoserine63 relationship: location_of CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: location_of CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: location_of CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: location_of CCO:B0014534 ! TRI37_HUMAN-Phosphoserine771 relationship: location_of CCO:B0014560 ! TYY1_HUMAN-Phosphoserine184 relationship: location_of CCO:B0014564 ! UBE3A_HUMAN-Phosphoserine218 relationship: location_of CCO:B0014675 ! WDR5_HUMAN-Phosphoserine267 relationship: location_of CCO:B0014698 ! WRN_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0014743 ! ZHX1_HUMAN-Phosphoserine48 relationship: location_of CCO:B0014746 ! ZNF24_HUMAN-Phosphoserine261 relationship: location_of CCO:B0015232 ! Q9NSP8_HUMAN relationship: location_of CCO:B0015235 ! Q8IVV0_HUMAN relationship: location_of CCO:B0015270 ! DFFB_HUMAN relationship: location_of CCO:B0015284 ! ARF3_HUMAN relationship: location_of CCO:B0015288 ! ARF1_HUMAN relationship: location_of CCO:B0015646 ! ERCC1_HUMAN relationship: location_of CCO:B0015701 ! Q8N6B5_HUMAN relationship: location_of CCO:B0015705 ! Q8NAN6_HUMAN relationship: location_of CCO:B0015706 ! Q0PRL4_HUMAN relationship: location_of CCO:B0015709 ! Q8N2P0_HUMAN relationship: location_of CCO:B0015710 ! Q7Z7F8_HUMAN relationship: location_of CCO:B0015712 ! FOXP1_HUMAN relationship: location_of CCO:B0015715 ! Q96AP5_HUMAN relationship: location_of CCO:B0015717 ! FOXP2_HUMAN relationship: location_of CCO:B0015718 ! Q68DX8_HUMAN relationship: location_of CCO:B0015719 ! Q8IW55_HUMAN relationship: location_of CCO:B0015721 ! A3KMG1_HUMAN relationship: location_of CCO:B0016257 ! Q9BR65_HUMAN relationship: location_of CCO:B0016356 ! Q6KH11_HUMAN relationship: location_of CCO:B0016357 ! Q6PCE1_HUMAN relationship: location_of CCO:B0016358 ! Q495L7_HUMAN relationship: location_of CCO:B0016364 ! Q5T7U6_HUMAN relationship: location_of CCO:B0016368 ! Q8TEP0_HUMAN relationship: location_of CCO:B0016369 ! Q6ZSD5_HUMAN relationship: location_of CCO:B0016789 ! Q7Z5R8_HUMAN relationship: location_of CCO:B0016794 ! PLAG1_HUMAN relationship: location_of CCO:B0016798 ! PLAL2_HUMAN relationship: location_of CCO:B0017097 ! Z816A_HUMAN relationship: location_of CCO:B0017101 ! ZN528_HUMAN relationship: location_of CCO:B0017103 ! ZNF83_HUMAN relationship: location_of CCO:B0017875 ! ZFP62_HUMAN relationship: location_of CCO:B0017876 ! Q6ZN27_HUMAN relationship: location_of CCO:B0017883 ! ZN616_HUMAN relationship: location_of CCO:B0017884 ! ZN546_HUMAN relationship: location_of CCO:B0018046 ! NXF1_HUMAN relationship: location_of CCO:B0018142 ! EVI5L_HUMAN relationship: location_of CCO:B0018381 ! A1L3Z2_HUMAN relationship: location_of CCO:B0018382 ! CREB5_HUMAN relationship: location_of CCO:B0018391 ! IQGA2_HUMAN relationship: location_of CCO:B0018465 ! ZN326_HUMAN relationship: location_of CCO:B0018552 ! Q4VXV6_HUMAN relationship: location_of CCO:B0018555 ! Q4VXV5_HUMAN relationship: location_of CCO:B0019050 ! A6NKB1_HUMAN relationship: location_of CCO:B0019132 ! RHG17_HUMAN relationship: location_of CCO:B0019134 ! A6NCP5_HUMAN relationship: location_of CCO:B0019340 ! SYGP1_HUMAN relationship: location_of CCO:B0019348 ! A2AB18_HUMAN relationship: location_of CCO:B0019350 ! NGAP_HUMAN relationship: location_of CCO:B0019420 ! Q53FN2_HUMAN relationship: location_of CCO:B0020438 ! A6NNS1_HUMAN relationship: location_of CCO:B0020567 ! Q9NXX9_HUMAN relationship: location_of CCO:B0020591 ! RHOA_HUMAN relationship: location_of CCO:B0020594 ! RHOC_HUMAN relationship: location_of CCO:B0020597 ! Q5JR08_HUMAN relationship: location_of CCO:B0020731 ! TAGAP_HUMAN relationship: location_of CCO:B0020932 ! GLIS1_HUMAN relationship: location_of CCO:B0020998 ! HELC1_HUMAN relationship: location_of CCO:B0021009 ! Q9UHS4_HUMAN relationship: location_of CCO:B0021015 ! Q5TBX5_HUMAN relationship: location_of CCO:B0021155 ! Q86VG0_HUMAN relationship: location_of CCO:B0021160 ! Q07644_HUMAN relationship: location_of CCO:B0021348 ! Q15959_HUMAN relationship: location_of CCO:B0021866 ! IKZF4_HUMAN relationship: location_of CCO:B0022038 ! ZHX2_HUMAN relationship: location_of CCO:B0022042 ! Q6NUJ7_HUMAN relationship: location_of CCO:B0022046 ! Q5JZ69_HUMAN relationship: location_of CCO:B0022073 ! SMC6_HUMAN relationship: location_of CCO:B0022152 ! Q4LE71_HUMAN relationship: location_of CCO:B0022381 ! ZN667_HUMAN relationship: location_of CCO:B0022382 ! Q9ULA1_HUMAN relationship: location_of CCO:B0022832 ! BCL6B_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022936 ! Q5TEW3_HUMAN relationship: location_of CCO:B0023371 ! HIC2_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0023936 ! Q9BZ74_HUMAN relationship: location_of CCO:B0023937 ! Q9H9L9_HUMAN relationship: location_of CCO:B0023961 ! Q8NIA3_HUMAN relationship: location_of CCO:B0024182 ! RPIA_HUMAN relationship: location_of CCO:B0024266 ! POGZ_HUMAN relationship: location_of CCO:B0024399 ! Q5U0C3_HUMAN relationship: location_of CCO:B0024407 ! RAP2C_HUMAN relationship: location_of CCO:B0024408 ! Q9BXV4_HUMAN relationship: location_of CCO:B0024477 ! BNC2_HUMAN relationship: location_of CCO:B0024595 ! Q2M2Z8_HUMAN relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0024600 ! CEND1_HUMAN relationship: location_of CCO:B0024694 ! BIG1_HUMAN relationship: location_of CCO:B0024794 ! ZIC3_HUMAN relationship: location_of CCO:B0024799 ! ZIC1_HUMAN relationship: location_of CCO:B0024847 ! Q15156_HUMAN relationship: location_of CCO:B0024942 ! Q6NVK3_HUMAN relationship: location_of CCO:B0025120 ! Q59FX3_HUMAN relationship: location_of CCO:B0025350 ! DIRA1_HUMAN relationship: location_of CCO:B0025365 ! OVOL2_HUMAN relationship: location_of CCO:B0025407 ! NFIX_HUMAN relationship: location_of CCO:B0025409 ! Q7Z3K7_HUMAN relationship: location_of CCO:B0025410 ! Q5W0Y9_HUMAN relationship: location_of CCO:B0025417 ! Q8TA97_HUMAN relationship: location_of CCO:B0025419 ! Q6ZNF9_HUMAN relationship: location_of CCO:B0025421 ! Q5VW27_HUMAN relationship: location_of CCO:B0025422 ! Q13051_HUMAN relationship: location_of CCO:B0025428 ! Q5VW30_HUMAN relationship: location_of CCO:B0025429 ! Q5VW29_HUMAN relationship: location_of CCO:B0025430 ! Q5VW26_HUMAN relationship: location_of CCO:B0025485 ! Q2A130_HUMAN relationship: location_of CCO:B0026103 ! SORCN_HUMAN relationship: location_of CCO:B0026336 ! AAPK1_HUMAN-Phosphoserine487 relationship: location_of CCO:B0026382 ! NF1_HUMAN-Phosphoserine2829 relationship: location_of CCO:B0026418 ! NUDT4_HUMAN relationship: location_of CCO:B0026583 ! SNX6_HUMAN relationship: location_of CCO:B0026606 ! Q05BV6_HUMAN relationship: location_of CCO:B0026813 ! CD014_HUMAN relationship: location_of CCO:B0027580 ! A0JNU9_HUMAN relationship: location_of CCO:B0027581 ! TBCD1_HUMAN relationship: location_of CCO:B0027846 ! A8K4V1_HUMAN relationship: location_of CCO:B0027932 ! Q6J1T2_HUMAN relationship: location_of CCO:B0027933 ! Q6J1T1_HUMAN relationship: location_of CCO:B0027936 ! Q14BD4_HUMAN relationship: location_of CCO:B0028281 ! ARL1_HUMAN relationship: location_of CCO:B0029042 ! ARHGF_HUMAN relationship: location_of CCO:B0029283 ! ZSC20_HUMAN relationship: location_of CCO:B0029287 ! A6NJN6_HUMAN relationship: location_of CCO:B0029451 ! Z3H7B_HUMAN relationship: location_of CCO:B0029592 ! RL36_HUMAN relationship: location_of CCO:B0030278 ! RND1_HUMAN relationship: location_of CCO:B0030280 ! RND2_HUMAN relationship: location_of CCO:B0030465 ! RS23_HUMAN relationship: location_of CCO:B0030604 ! A8K7W5_HUMAN relationship: location_of CCO:B0030726 ! TB22B_HUMAN relationship: location_of CCO:B0030729 ! TB22A_HUMAN relationship: location_of CCO:B0030841 ! Q7Z7F1_HUMAN relationship: location_of CCO:B0031117 ! Q4LE74_HUMAN relationship: location_of CCO:B0031334 ! HSP7C_HUMAN-Phosphotyrosine41 relationship: location_of CCO:B0031753 ! Q5T270_HUMAN relationship: location_of CCO:B0032351 ! A6NLC3_HUMAN relationship: location_of CCO:B0032352 ! Q7Z2R1_HUMAN relationship: location_of CCO:B0032357 ! Q6NVI0_HUMAN relationship: location_of CCO:B0032358 ! Q7Z7K8_HUMAN relationship: location_of CCO:B0032362 ! Q6ZNF3_HUMAN relationship: location_of CCO:B0032363 ! ZN738_HUMAN relationship: location_of CCO:B0032364 ! Q96QM1_HUMAN relationship: location_of CCO:B0032365 ! A6NEM4_HUMAN relationship: location_of CCO:B0032368 ! Q75LP1_HUMAN relationship: location_of CCO:B0032369 ! Q6NS90_HUMAN relationship: location_of CCO:B0032438 ! FBX8_HUMAN relationship: location_of CCO:B0032439 ! Q8IWE1_HUMAN relationship: location_of CCO:B0032440 ! Q8IXA8_HUMAN relationship: location_of CCO:B0032516 ! A8MUV4_HUMAN relationship: location_of CCO:B0032556 ! Q504R6_HUMAN relationship: location_of CCO:B0032841 ! DBF4A_HUMAN-Phosphoserine539 relationship: location_of CCO:B0033001 ! RS27_HUMAN relationship: location_of CCO:B0033316 ! DEST_HUMAN relationship: location_of CCO:B0033320 ! COF1_HUMAN relationship: location_of CCO:B0033512 ! RBG1L_HUMAN relationship: location_of CCO:B0033513 ! Q5JZA9_HUMAN relationship: location_of CCO:B0033633 ! RL13_HUMAN relationship: location_of CCO:B0034094 ! RHG28_HUMAN relationship: location_of CCO:B0034095 ! A8MQB7_HUMAN relationship: location_of CCO:B0034099 ! A8MU88_HUMAN relationship: location_of CCO:B0034678 ! COF2_HUMAN-Phosphoserine3 relationship: location_of CCO:B0034822 ! G3BP1_HUMAN-Omega-N-methylated arginine460 relationship: location_of CCO:B0034826 ! G3BP2_HUMAN-Phosphoserine225 relationship: location_of CCO:B0034880 ! IQGA1_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0035072 ! KPCT_HUMAN-Phosphoserine695 relationship: location_of CCO:B0035383 ! PKN2_HUMAN-Phosphoserine360 relationship: location_of CCO:B0035392 ! PKN3_HUMAN-Phosphoserine544 relationship: location_of CCO:B0035507 ! RAP1B_HUMAN-ADP-ribosylserine39 relationship: location_of CCO:B0035510 ! RAP2A_HUMAN-Cysteine methyl ester180 relationship: location_of CCO:B0035511 ! RAP2B_HUMAN-Cysteine methyl ester180 relationship: location_of CCO:B0035571 ! RHG07_HUMAN-Phosphoserine305 relationship: location_of CCO:B0035594 ! RND3_HUMAN-Cysteine methyl ester241 relationship: location_of CCO:B0035599 ! RRAS2_HUMAN-Cysteine methyl ester201 relationship: location_of CCO:B0035600 ! RRAS_HUMAN-Cysteine methyl ester215 relationship: location_of CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: location_of CCO:B0035762 ! TBC13_HUMAN-Phosphoserine108 relationship: location_of CCO:B0035773 ! TGFI1_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0035836 ! XRCC1_HUMAN-Phosphoserine266 relationship: location_of CCO:B0036028 ! RL21_HUMAN-Phosphothreonine47 relationship: location_of CCO:B0037015 ! Q1ZYL3_HUMAN relationship: location_of CCO:B0037017 ! ARHG4_HUMAN relationship: location_of CCO:B0037018 ! PREX2_HUMAN relationship: location_of CCO:B0037019 ! SPT13_HUMAN relationship: location_of CCO:B0037020 ! DEPD6_HUMAN relationship: location_of CCO:B0037023 ! Q5VX68_HUMAN relationship: location_of CCO:B0037024 ! ARHG9_HUMAN relationship: location_of CCO:B0037049 ! TRI66_HUMAN relationship: location_of CCO:B0037050 ! TRI33_HUMAN relationship: location_of CCO:B0037051 ! TIF1A_HUMAN relationship: location_of CCO:B0037089 ! ZN100_HUMAN relationship: location_of CCO:B0037090 ! ZN479_HUMAN relationship: location_of CCO:B0037092 ! ZN682_HUMAN relationship: location_of CCO:B0037093 ! ZN680_HUMAN relationship: location_of CCO:B0037094 ! Q6ZMM5_HUMAN relationship: location_of CCO:B0037096 ! ZN626_HUMAN relationship: location_of CCO:B0037097 ! Q96M04_HUMAN relationship: location_of CCO:B0037101 ! ZN431_HUMAN relationship: location_of CCO:B0037103 ! A4FVA7_HUMAN relationship: location_of CCO:B0037105 ! ZN273_HUMAN relationship: location_of CCO:B0037109 ! O95779_HUMAN relationship: location_of CCO:B0037110 ! ZNF92_HUMAN relationship: location_of CCO:B0037112 ! ZN430_HUMAN relationship: location_of CCO:B0037138 ! ZF64B_HUMAN relationship: location_of CCO:B0037139 ! ZF64A_HUMAN relationship: location_of CCO:B0037522 ! A2RQD6_HUMAN relationship: location_of CCO:B0037765 ! OVL2L_HUMAN relationship: location_of CCO:B0037974 ! ZNF81_HUMAN relationship: location_of CCO:B0037975 ! ZN175_HUMAN relationship: location_of CCO:B0037997 ! Q5JT61_HUMAN relationship: location_of CCO:B0038000 ! Q5JS12_HUMAN relationship: location_of CCO:B0038002 ! Q8N7G9_HUMAN relationship: location_of CCO:B0038093 ! ABI3_HUMAN relationship: location_of CCO:B0038152 ! ZN446_HUMAN relationship: location_of CCO:B0038370 ! IKZF3_HUMAN relationship: location_of CCO:B0038386 ! Q5JUE5_HUMAN relationship: location_of CCO:B0038390 ! Q5JUE9_HUMAN relationship: location_of CCO:B0038391 ! Q8IV73_HUMAN relationship: location_of CCO:B0038625 ! Q96M79_HUMAN relationship: location_of CCO:B0038627 ! ZNF19_HUMAN relationship: location_of CCO:B0039094 ! ZN776_HUMAN relationship: location_of CCO:B0039095 ! ZN773_HUMAN relationship: location_of CCO:B0039097 ! A6NLI9_HUMAN relationship: location_of CCO:B0039099 ! A6NJK9_HUMAN relationship: location_of CCO:B0039101 ! ZN548_HUMAN relationship: location_of CCO:B0039102 ! ZN419_HUMAN relationship: location_of CCO:B0039103 ! A6NKR6_HUMAN relationship: location_of CCO:B0039104 ! ZN134_HUMAN relationship: location_of CCO:B0039105 ! ZN772_HUMAN relationship: location_of CCO:B0039107 ! A6NNZ3_HUMAN relationship: location_of CCO:B0039108 ! ZN211_HUMAN relationship: location_of CCO:B0039109 ! ZIK1_HUMAN relationship: location_of CCO:B0039112 ! A6NL30_HUMAN relationship: location_of CCO:B0039113 ! Q59EG4_HUMAN relationship: location_of CCO:B0039114 ! ZN154_HUMAN relationship: location_of CCO:B0039117 ! A6NGN8_HUMAN relationship: location_of CCO:B0039118 ! Q2TAL7_HUMAN relationship: location_of CCO:B0039119 ! Q59FT8_HUMAN relationship: location_of CCO:B0039332 ! BRPF1_HUMAN-Phosphoserine922 relationship: location_of CCO:B0039437 ! FOXP4_HUMAN-Phosphoserine360 relationship: location_of CCO:B0039470 ! IKZF2_HUMAN-Phosphoserine174 relationship: location_of CCO:B0039484 ! LIPB2_HUMAN-Phosphoserine385 relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0039596 ! PREX1_HUMAN-Phosphoserine436 relationship: location_of CCO:B0039618 ! RGPS2_HUMAN-Phosphoserine343 relationship: location_of CCO:B0039640 ! RPGF1_HUMAN-Phosphoserine360 relationship: location_of CCO:B0039718 ! ZN295_HUMAN-Phosphoserine411 relationship: location_of CCO:B0039725 ! ZN429_HUMAN-Phosphothreonine364 relationship: location_of CCO:B0039811 ! BIRC6_HUMAN relationship: location_of CCO:B0039936 ! RHEB_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0039948 ! ZFP42_HUMAN relationship: location_of CCO:B0039949 ! FSD1_HUMAN relationship: location_of CCO:B0040141 ! B0I1T6_HUMAN relationship: location_of CCO:B0040467 ! CASP1_HUMAN relationship: location_of CCO:B0040469 ! Q5FBZ0_HUMAN relationship: location_of CCO:B0040471 ! CASP4_HUMAN relationship: location_of CCO:B0040472 ! INCA_HUMAN relationship: location_of CCO:B0040474 ! ICBR_HUMAN relationship: location_of CCO:B0040476 ! O95601_HUMAN relationship: location_of CCO:B0040477 ! Q0QVY8_HUMAN relationship: location_of CCO:B0040479 ! Q0QVY7_HUMAN relationship: location_of CCO:B0040484 ! CASP5_HUMAN relationship: location_of CCO:B0040485 ! CASPC_HUMAN relationship: location_of CCO:B0040488 ! Q96RJ9_HUMAN relationship: location_of CCO:B0040491 ! COP_HUMAN relationship: location_of CCO:B0040516 ! RS14_HUMAN relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0040684 ! REBL1_HUMAN relationship: location_of CCO:B0040686 ! NC2A_HUMAN relationship: location_of CCO:B0041173 ! RASH_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041257 ! E4F1_HUMAN relationship: location_of CCO:B0041371 ! RHG15_HUMAN relationship: location_of CCO:B0041373 ! Q1RLN5_HUMAN relationship: location_of CCO:B0041474 ! B1AHC4_HUMAN relationship: location_of CCO:B0041548 ! SYF1_HUMAN relationship: location_of CCO:B0041721 ! B0QY80_HUMAN relationship: location_of CCO:B0041800 ! CAN1_HUMAN relationship: location_of CCO:B0041821 ! CAN2_HUMAN relationship: location_of CCO:B0041822 ! CAN5_HUMAN relationship: location_of CCO:B0041843 ! TYY2_HUMAN relationship: location_of CCO:B0042225 ! GRM4_HUMAN relationship: location_of CCO:B0042229 ! Q8NHA9_HUMAN relationship: location_of CCO:B0042239 ! GRM2_HUMAN relationship: location_of CCO:B0042545 ! B1AL79_HUMAN relationship: location_of CCO:B0042581 ! B1AMV0_HUMAN relationship: location_of CCO:B0042582 ! B1AMV1_HUMAN relationship: location_of CCO:B0042583 ! B1AMV2_HUMAN relationship: location_of CCO:B0043283 ! GLIS2_HUMAN-Phosphoserine245 relationship: location_of CCO:B0043353 ! RHG12_HUMAN-Phosphoserine240 relationship: location_of CCO:B0043358 ! RHG27_HUMAN-Phosphotyrosine228 relationship: location_of CCO:B0043382 ! STAR8_HUMAN-Phosphoserine238 relationship: location_of CCO:B0043426 ! TRIM9_HUMAN relationship: location_of CCO:B0043435 ! FBX41_HUMAN relationship: location_of CCO:B0043495 ! TRI39_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0043507 ! XRN2_HUMAN-Phosphoserine501 relationship: location_of CCO:B0043592 ! RL23_HUMAN relationship: location_of CCO:B0043825 ! RS15A_HUMAN relationship: location_of CCO:B0048182 ! CCND1_HUMAN-Phosphotyrosine226 relationship: location_of CCO:B0048271 ! GRLF1_HUMAN-Phosphoserine970 relationship: location_of CCO:B0048315 ! MATR3_HUMAN-Phosphoserine206 relationship: location_of CCO:B0048358 ! PR285_HUMAN-Phosphotyrosine1507 relationship: location_of CCO:B0048411 ! TIF1B_HUMAN-Phosphoserine49 relationship: location_of CCO:B0048588 ! ZN675_HUMAN relationship: location_of CCO:B0048590 ! ZNF98_HUMAN relationship: location_of CCO:B0048591 ! Q4G131_HUMAN relationship: location_of CCO:B0048593 ! ZN714_HUMAN relationship: location_of CCO:B0048595 ! ZN737_HUMAN relationship: location_of CCO:B0048898 ! RGPS1_HUMAN relationship: location_of CCO:B0049558 ! HG2A_HUMAN relationship: location_of CCO:B0049842 ! ZSC16_HUMAN relationship: location_of CCO:B0049905 ! Q24JP0_HUMAN relationship: location_of CCO:B0050112 ! ZN566_HUMAN relationship: location_of CCO:B0050113 ! ZN582_HUMAN relationship: location_of CCO:B0050221 ! ZN75A_HUMAN relationship: location_of CCO:B0050222 ! Q5JPG0_HUMAN relationship: location_of CCO:B0050223 ! A6NK62_HUMAN relationship: location_of CCO:B0050534 ! CNOT8_HUMAN relationship: location_of CCO:B0050679 ! ARI5B_HUMAN relationship: location_of CCO:B0050867 ! ZN487_HUMAN relationship: location_of CCO:B0051199 ! RP1BL_HUMAN relationship: location_of CCO:B0051353 ! GBRL1_HUMAN relationship: location_of CCO:B0051400 ! YS018_HUMAN relationship: location_of CCO:B0051401 ! B1AKC7_HUMAN relationship: location_of CCO:B0051775 ! ZN277_HUMAN relationship: location_of CCO:B0052286 ! ARI5B_HUMAN-Phosphoserine1002 relationship: location_of CCO:B0052399 ! GBRL2_HUMAN-Phosphoserine10 relationship: location_of CCO:B0053697 ! A0AUX1_HUMAN relationship: location_of CCO:B0053699 ! A0AVJ9_HUMAN relationship: location_of CCO:B0053704 ! FEZF1_HUMAN relationship: location_of CCO:B0053705 ! RHG10_HUMAN relationship: location_of CCO:B0053707 ! A1A4T9_HUMAN relationship: location_of CCO:B0053710 ! YE018_HUMAN relationship: location_of CCO:B0053713 ! A1L4L9_HUMAN relationship: location_of CCO:B0053716 ! A2A2E9_HUMAN relationship: location_of CCO:B0053723 ! A2AGP5_HUMAN relationship: location_of CCO:B0053729 ! A2BFK5_HUMAN relationship: location_of CCO:B0053736 ! ZN320_HUMAN relationship: location_of CCO:B0053739 ! A2RU51_HUMAN relationship: location_of CCO:B0053741 ! A2VBQ3_HUMAN relationship: location_of CCO:B0053747 ! A3KN82_HUMAN relationship: location_of CCO:B0053757 ! A4D2A4_HUMAN relationship: location_of CCO:B0053761 ! A4D2P2_HUMAN relationship: location_of CCO:B0053763 ! A4FU53_HUMAN relationship: location_of CCO:B0053769 ! A4Q9G8_HUMAN relationship: location_of CCO:B0053770 ! A4Q9G9_HUMAN relationship: location_of CCO:B0053775 ! PSD1_HUMAN relationship: location_of CCO:B0053776 ! A5PLP1_HUMAN relationship: location_of CCO:B0053777 ! A5XEI4_HUMAN relationship: location_of CCO:B0053778 ! A5XEI5_HUMAN relationship: location_of CCO:B0053779 ! A5XEI9_HUMAN relationship: location_of CCO:B0053790 ! A6NDI7_HUMAN relationship: location_of CCO:B0053792 ! A6NDL0_HUMAN relationship: location_of CCO:B0053794 ! A6NDQ6_HUMAN relationship: location_of CCO:B0053796 ! TBC3B_HUMAN relationship: location_of CCO:B0053798 ! YT007_HUMAN relationship: location_of CCO:B0053799 ! A6NDX7_HUMAN relationship: location_of CCO:B0053802 ! A6NE50_HUMAN relationship: location_of CCO:B0053808 ! SSX10_HUMAN relationship: location_of CCO:B0053809 ! TBC3E_HUMAN relationship: location_of CCO:B0053812 ! A6NF07_HUMAN relationship: location_of CCO:B0053814 ! YS053_HUMAN relationship: location_of CCO:B0053815 ! ZN734_HUMAN relationship: location_of CCO:B0053820 ! A6NFE1_HUMAN relationship: location_of CCO:B0053821 ! ZN316_HUMAN relationship: location_of CCO:B0053822 ! A6NFK4_HUMAN relationship: location_of CCO:B0053828 ! A6NG70_HUMAN relationship: location_of CCO:B0053830 ! A6NG99_HUMAN relationship: location_of CCO:B0053831 ! ZSA5C_HUMAN relationship: location_of CCO:B0053832 ! YR003_HUMAN relationship: location_of CCO:B0053837 ! ZB12L_HUMAN relationship: location_of CCO:B0053838 ! TBC3L_HUMAN relationship: location_of CCO:B0053840 ! ARL5C_HUMAN relationship: location_of CCO:B0053841 ! A6NH61_HUMAN relationship: location_of CCO:B0053846 ! A6NHE2_HUMAN relationship: location_of CCO:B0053848 ! ZN860_HUMAN relationship: location_of CCO:B0053853 ! A6NHY0_HUMAN relationship: location_of CCO:B0053856 ! A6NI23_HUMAN relationship: location_of CCO:B0053857 ! RH10L_HUMAN relationship: location_of CCO:B0053858 ! TB3L2_HUMAN relationship: location_of CCO:B0053859 ! A6NIB0_HUMAN relationship: location_of CCO:B0053860 ! A6NIF2_HUMAN relationship: location_of CCO:B0053867 ! A6NJ28_HUMAN relationship: location_of CCO:B0053868 ! A6NJ38_HUMAN relationship: location_of CCO:B0053871 ! A6NJH0_HUMAN relationship: location_of CCO:B0053873 ! ZSA5B_HUMAN relationship: location_of CCO:B0053876 ! YI017_HUMAN relationship: location_of CCO:B0053877 ! YM010_HUMAN relationship: location_of CCO:B0053878 ! ZN233_HUMAN relationship: location_of CCO:B0053881 ! A6NKB0_HUMAN relationship: location_of CCO:B0053883 ! ARI3C_HUMAN relationship: location_of CCO:B0053885 ! 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A8K007_HUMAN relationship: location_of CCO:B0053955 ! A8K1S9_HUMAN relationship: location_of CCO:B0053958 ! A8K2Y1_HUMAN relationship: location_of CCO:B0053965 ! A8K3P5_HUMAN relationship: location_of CCO:B0053968 ! A8K5A9_HUMAN relationship: location_of CCO:B0053970 ! A8K5N8_HUMAN relationship: location_of CCO:B0053972 ! A8K6J1_HUMAN relationship: location_of CCO:B0053974 ! A8K6Z7_HUMAN relationship: location_of CCO:B0053975 ! A8K6Z9_HUMAN relationship: location_of CCO:B0053976 ! A8K7H5_HUMAN relationship: location_of CCO:B0053977 ! A8K7K1_HUMAN relationship: location_of CCO:B0053979 ! A8K8E1_HUMAN relationship: location_of CCO:B0053981 ! Z705D_HUMAN relationship: location_of CCO:B0053983 ! A8K9Z8_HUMAN relationship: location_of CCO:B0053984 ! A8KAD2_HUMAN relationship: location_of CCO:B0053985 ! A8MPQ0_HUMAN relationship: location_of CCO:B0053988 ! A8MPS8_HUMAN relationship: location_of CCO:B0053989 ! A8MPT8_HUMAN relationship: location_of CCO:B0053991 ! 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RHOF_HUMAN relationship: location_of CCO:B0058789 ! Q9HBR4_HUMAN relationship: location_of CCO:B0058790 ! ZN287_HUMAN relationship: location_of CCO:B0058791 ! Z286A_HUMAN relationship: location_of CCO:B0058795 ! NOD2_HUMAN relationship: location_of CCO:B0058799 ! ZBT20_HUMAN relationship: location_of CCO:B0058800 ! CAN10_HUMAN relationship: location_of CCO:B0058805 ! SMUF1_HUMAN relationship: location_of CCO:B0058809 ! ZBT26_HUMAN relationship: location_of CCO:B0058811 ! ZFP14_HUMAN relationship: location_of CCO:B0058812 ! PLXA4_HUMAN relationship: location_of CCO:B0058820 ! ZN304_HUMAN relationship: location_of CCO:B0058822 ! ZN334_HUMAN relationship: location_of CCO:B0058827 ! Q9HD74_HUMAN relationship: location_of CCO:B0058847 ! MYNN_HUMAN relationship: location_of CCO:B0058856 ! NLRC4_HUMAN relationship: location_of CCO:B0058857 ! SCRT2_HUMAN relationship: location_of CCO:B0058873 ! PRD10_HUMAN relationship: location_of CCO:B0058874 ! PRDM9_HUMAN relationship: location_of CCO:B0058875 ! PRDM8_HUMAN relationship: location_of CCO:B0058876 ! PRDM7_HUMAN relationship: location_of CCO:B0058878 ! PRDM6_HUMAN relationship: location_of CCO:B0058879 ! PRDM5_HUMAN relationship: location_of CCO:B0058880 ! ZN331_HUMAN relationship: location_of CCO:B0058881 ! ZNF71_HUMAN relationship: location_of CCO:B0058882 ! ZN302_HUMAN relationship: location_of CCO:B0058885 ! SAR1A_HUMAN relationship: location_of CCO:B0058889 ! ARHG3_HUMAN relationship: location_of CCO:B0058890 ! S2A4R_HUMAN relationship: location_of CCO:B0058898 ! TSH2_HUMAN relationship: location_of CCO:B0058917 ! ZN275_HUMAN relationship: location_of CCO:B0058921 ! ZN834_HUMAN relationship: location_of CCO:B0058926 ! ZFP57_HUMAN relationship: location_of CCO:B0058929 ! ZN701_HUMAN relationship: location_of CCO:B0058935 ! ZN358_HUMAN relationship: location_of CCO:B0058946 ! DDT4_HUMAN relationship: location_of CCO:B0058950 ! ZN434_HUMAN relationship: location_of CCO:B0058955 ! YD003_HUMAN relationship: location_of CCO:B0058956 ! ZN586_HUMAN relationship: location_of CCO:B0058961 ! FA13B_HUMAN relationship: location_of CCO:B0058969 ! KBRS2_HUMAN relationship: location_of CCO:B0058973 ! ZN226_HUMAN relationship: location_of CCO:B0058985 ! RBAK_HUMAN relationship: location_of CCO:B0059001 ! MTCH1_HUMAN relationship: location_of CCO:B0059004 ! ZN224_HUMAN relationship: location_of CCO:B0059021 ! ZIM2_HUMAN relationship: location_of CCO:B0059027 ! Q9P0G0_HUMAN relationship: location_of CCO:B0059030 ! ZN167_HUMAN relationship: location_of CCO:B0059033 ! TBCD7_HUMAN relationship: location_of CCO:B0059046 ! ZBTB4_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059049 ! POGK_HUMAN relationship: location_of CCO:B0059052 ! ZFAT_HUMAN relationship: location_of CCO:B0059053 ! ZN492_HUMAN relationship: location_of CCO:B0059057 ! ZN319_HUMAN relationship: location_of CCO:B0059060 ! TBC14_HUMAN relationship: location_of CCO:B0059092 ! REV1_HUMAN relationship: location_of CCO:B0059093 ! Q9UC05_HUMAN relationship: location_of CCO:B0059094 ! ZNF70_HUMAN relationship: location_of CCO:B0059095 ! ZNF69_HUMAN relationship: location_of CCO:B0059104 ! ZN212_HUMAN relationship: location_of CCO:B0059105 ! ZN282_HUMAN relationship: location_of CCO:B0059109 ! ZN629_HUMAN relationship: location_of CCO:B0059114 ! ZBT47_HUMAN relationship: location_of CCO:B0059115 ! Q9UFT8_HUMAN relationship: location_of CCO:B0059116 ! TBC29_HUMAN relationship: location_of CCO:B0059124 ! JAD1B_HUMAN relationship: location_of CCO:B0059129 ! Q9UH66_HUMAN relationship: location_of CCO:B0059143 ! NUFP1_HUMAN relationship: location_of CCO:B0059149 ! Q9UHV4_HUMAN relationship: location_of CCO:B0059150 ! RPGFL_HUMAN relationship: location_of CCO:B0059155 ! CYH4_HUMAN relationship: location_of CCO:B0059158 ! ZN230_HUMAN relationship: location_of CCO:B0059162 ! KLF15_HUMAN relationship: location_of CCO:B0059163 ! ZN107_HUMAN relationship: location_of CCO:B0059172 ! ZN643_HUMAN relationship: location_of CCO:B0059174 ! SALL4_HUMAN relationship: location_of CCO:B0059176 ! ZF112_HUMAN relationship: location_of CCO:B0059177 ! DBNL_HUMAN relationship: location_of CCO:B0059178 ! ZN229_HUMAN relationship: location_of CCO:B0059184 ! ZN223_HUMAN relationship: location_of CCO:B0059185 ! ZN222_HUMAN relationship: location_of CCO:B0059186 ! ZN221_HUMAN relationship: location_of CCO:B0059192 ! PITC1_HUMAN relationship: location_of CCO:B0059197 ! PRDM4_HUMAN relationship: location_of CCO:B0059207 ! VAV3_HUMAN relationship: location_of CCO:B0059216 ! ZN236_HUMAN relationship: location_of CCO:B0059218 ! ZN215_HUMAN relationship: location_of CCO:B0059219 ! ZN214_HUMAN relationship: location_of CCO:B0059222 ! ZN777_HUMAN relationship: location_of CCO:B0059229 ! ZN490_HUMAN relationship: location_of CCO:B0059231 ! TBC24_HUMAN relationship: location_of CCO:B0059248 ! RHG26_HUMAN relationship: location_of CCO:B0059249 ! POLI_HUMAN relationship: location_of CCO:B0059252 ! Q9UNJ2_HUMAN relationship: location_of CCO:B0059257 ! ZN232_HUMAN relationship: location_of CCO:B0059262 ! IQEC3_HUMAN relationship: location_of CCO:B0059263 ! CENG2_HUMAN relationship: location_of CCO:B0059264 ! TRI35_HUMAN relationship: location_of CCO:B0059267 ! ZN409_HUMAN relationship: location_of CCO:B0059275 ! Q9UQ19_HUMAN relationship: location_of CCO:B0059279 ! Q9UQD2_HUMAN relationship: location_of CCO:B0059290 ! NOD1_HUMAN relationship: location_of CCO:B0059303 ! CARD8_HUMAN relationship: location_of CCO:B0059304 ! ZFP30_HUMAN relationship: location_of CCO:B0059306 ! ZN510_HUMAN relationship: location_of CCO:B0059308 ! TBC30_HUMAN relationship: location_of CCO:B0059309 ! ZBTB1_HUMAN relationship: location_of CCO:B0059310 ! ZKSC5_HUMAN relationship: location_of CCO:B0059311 ! ZN835_HUMAN relationship: location_of CCO:B0059312 ! ZN256_HUMAN relationship: location_of CCO:B0059313 ! ZN257_HUMAN relationship: location_of CCO:B0059324 ! ZBT32_HUMAN relationship: location_of CCO:B0059326 ! KLF13_HUMAN relationship: location_of CCO:B0059338 ! 3BP1_HUMAN relationship: location_of CCO:B0059340 ! ZN337_HUMAN relationship: location_of CCO:B0059346 ! Q9Y408_HUMAN relationship: location_of CCO:B0059348 ! ZN711_HUMAN relationship: location_of CCO:B0059359 ! PLXD1_HUMAN relationship: location_of CCO:B0059362 ! RPGF2_HUMAN relationship: location_of CCO:B0059364 ! Q9Y4I4_HUMAN relationship: location_of CCO:B0059366 ! KLF12_HUMAN relationship: location_of CCO:B0059367 ! Q9Y4Y3_HUMAN relationship: location_of CCO:B0059373 ! ASB1_HUMAN relationship: location_of CCO:B0059375 ! ZSC21_HUMAN relationship: location_of CCO:B0059388 ! KLF2_HUMAN relationship: location_of CCO:B0059399 ! ARL5A_HUMAN relationship: location_of CCO:B0059403 ! SAR1B_HUMAN relationship: location_of CCO:B0059406 ! WSB1_HUMAN relationship: location_of CCO:B0059415 ! Z780B_HUMAN relationship: location_of CCO:B0059422 ! Q9Y6Y6_HUMAN relationship: location_of CCO:B0062791 ! NECP2_HUMAN relationship: location_of CCO:B0062794 ! TRI32_HUMAN relationship: location_of CCO:B0062803 ! APEX2_HUMAN relationship: location_of CCO:B0062823 ! HPCL4_HUMAN relationship: location_of CCO:B0062853 ! GNL3L_HUMAN relationship: location_of CCO:B0062872 ! IMP3_HUMAN relationship: location_of CCO:B0062874 ! TRI31_HUMAN relationship: location_of CCO:B0062877 ! Q8TBE5_HUMAN relationship: location_of CCO:B0062885 ! RL9_HUMAN relationship: location_of CCO:B0062892 ! RO52_HUMAN relationship: location_of CCO:B0062909 ! RLP24_HUMAN relationship: location_of CCO:B0062915 ! NCALD_HUMAN relationship: location_of CCO:B0062930 ! RT18B_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0063027 ! ZRAN1_HUMAN relationship: location_of CCO:B0063048 ! RL35A_HUMAN relationship: location_of CCO:B0063050 ! RLA0L_HUMAN relationship: location_of CCO:B0063053 ! ARHG2_HUMAN relationship: location_of CCO:B0063057 ! SYVC_HUMAN relationship: location_of CCO:B0063061 ! RS5_HUMAN relationship: location_of CCO:B0063078 ! RS16_HUMAN relationship: location_of CCO:B0063083 ! RL3_HUMAN relationship: location_of CCO:B0063091 ! RL35_HUMAN relationship: location_of CCO:B0063093 ! RL10_HUMAN relationship: location_of CCO:B0063127 ! Q96TA9_HUMAN relationship: location_of CCO:B0063196 ! TRIM2_HUMAN relationship: location_of CCO:B0063207 ! CYTB_HUMAN relationship: location_of CCO:B0063219 ! RN138_HUMAN relationship: location_of CCO:B0063255 ! CN37_HUMAN relationship: location_of CCO:B0063270 ! DZIP1_HUMAN relationship: location_of CCO:B0063294 ! IL1RA_HUMAN relationship: location_of CCO:B0063306 ! Z804A_HUMAN relationship: location_of CCO:B0063333 ! Q5SQU0_HUMAN relationship: location_of CCO:B0063350 ! TRI11_HUMAN relationship: location_of CCO:B0063353 ! RS26_HUMAN relationship: location_of CCO:B0063356 ! RL27A_HUMAN relationship: location_of CCO:B0063360 ! RL23A_HUMAN relationship: location_of CCO:B0063368 ! RS28_HUMAN relationship: location_of CCO:B0063385 ! RM44_HUMAN relationship: location_of CCO:B0063453 ! DRG1_HUMAN relationship: location_of CCO:B0063474 ! RS2_HUMAN relationship: location_of CCO:B0063479 ! NUDT5_HUMAN relationship: location_of CCO:B0063539 ! TRI16_HUMAN relationship: location_of CCO:B0063544 ! ARHG8_HUMAN-Phosphoserine106 relationship: location_of CCO:B0063545 ! ARHGB_HUMAN-Phosphoserine663 relationship: location_of CCO:B0063552 ! ARHGC_HUMAN-Phosphoserine1288 relationship: location_of CCO:B0063561 ! ARHGH_HUMAN-Phosphoserine138 relationship: location_of CCO:B0063567 ! ARHGI_HUMAN-Phosphoserine1124 relationship: location_of CCO:B0063573 ! ARI1B_HUMAN-Phosphoserine1559 relationship: location_of CCO:B0063575 ! ARI3A_HUMAN-Phosphoserine81 relationship: location_of CCO:B0063588 ! ARI4B_HUMAN-Phosphoserine1159 relationship: location_of CCO:B0063596 ! ARL14_HUMAN-Phosphotyrosine31 relationship: location_of CCO:B0063652 ! ATF2_HUMAN-Phosphothreonine71 relationship: location_of CCO:B0063685 ! AVEN_HUMAN-Phosphoserine94 relationship: location_of CCO:B0063688 ! AXN2_HUMAN-Phosphothreonine640 relationship: location_of CCO:B0063920 ! BIG2_HUMAN-Phosphoserine1514 relationship: location_of CCO:B0063923 ! BIG3_HUMAN-Phosphoserine1651 relationship: location_of CCO:B0063925 ! BIRC4_HUMAN-Phosphoserine87 relationship: location_of CCO:B0063939 ! BLNK_HUMAN-Phosphotyrosine178 relationship: location_of CCO:B0063945 ! BNC1_HUMAN-Phosphoserine537 relationship: location_of CCO:B0064067 ! CAR14_HUMAN-Phosphoserine544 relationship: location_of CCO:B0064068 ! CARD6_HUMAN-Phosphoserine468 relationship: location_of CCO:B0064082 ! CASP9_HUMAN-Phosphoserine307 relationship: location_of CCO:B0064229 ! CDGAP_HUMAN-Phosphoserine1106 relationship: location_of CCO:B0064259 ! CEND2_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0064268 ! CENG1_HUMAN-Phosphoserine865 relationship: location_of CCO:B0064274 ! CENG3_HUMAN-Phosphoserine336 relationship: location_of CCO:B0064355 ! CIDEB_HUMAN-Phosphoserine17 relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0064744 ! DFFA_HUMAN-Phosphoserine315 relationship: location_of CCO:B0064748 ! DGCR8_HUMAN-Phosphoserine271 relationship: location_of CCO:B0064811 ! DNLI3_HUMAN-Phosphothreonine122 relationship: location_of CCO:B0064815 ! DNLI4_HUMAN-Phosphothreonine347 relationship: location_of CCO:B0064856 ! DPOLL_HUMAN-Phosphoserine246 relationship: location_of CCO:B0064857 ! DPOLM_HUMAN-Phosphoserine12 relationship: location_of CCO:B0064879 ! DREB_HUMAN-Phosphothreonine331 relationship: location_of CCO:B0064880 ! DRG2_HUMAN-Phosphoserine199 relationship: location_of CCO:B0064885 ! DSRAD_HUMAN-Phosphothreonine808 relationship: location_of CCO:B0064911 ! E2AK4_HUMAN-Phosphoserine230 relationship: location_of CCO:B0065046 ! EM55_HUMAN-Phosphoserine19 relationship: location_of CCO:B0065454 ! AEBP2_HUMAN-Phosphoserine27 relationship: location_of CCO:B0065565 ! AKP13_HUMAN-Phosphoserine1929 relationship: location_of CCO:B0065574 ! AKP8L_HUMAN-Phosphoserine297 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0065655 ! ANXA5_HUMAN-Phosphotyrosine94 relationship: location_of CCO:B0065709 ! ARGAL_HUMAN-Phosphotyrosine131 relationship: location_of CCO:B0065734 ! ARHG5_HUMAN-Phosphotyrosine1100 relationship: location_of CCO:B0065740 ! ARHG6_HUMAN-Phosphoserine640 relationship: location_of CCO:B0065743 ! ARHG7_HUMAN-Phosphoserine176 relationship: location_of CCO:B0065856 ! CHM2B_HUMAN-Phosphoserine199 relationship: location_of CCO:B0066128 ! FARP1_HUMAN-Phosphoserine896 relationship: location_of CCO:B0066133 ! FARP2_HUMAN-Phosphoserine881 relationship: location_of CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: location_of CCO:B0066179 ! FGD3_HUMAN-Phosphoserine128 relationship: location_of CCO:B0066183 ! FGD6_HUMAN-Phosphoserine721 relationship: location_of CCO:B0066197 ! FIZ1_HUMAN-Phosphothreonine74 relationship: location_of CCO:B0066317 ! FUS_HUMAN-Omega-N-methylated arginine216 relationship: location_of CCO:B0066377 ! GAPD1_HUMAN-Phosphoserine966 relationship: location_of CCO:B0066381 ! GARL3_HUMAN-Phosphothreonine827 relationship: location_of CCO:B0066479 ! GMIP_HUMAN-Phosphoserine437 relationship: location_of CCO:B0066498 ! GNL1_HUMAN-Phosphoserine68 relationship: location_of CCO:B0066616 ! GRIPE_HUMAN-Phosphoserine860 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0066835 ! HMHA1_HUMAN-Phosphoserine25 relationship: location_of CCO:B0066934 ! HSPB8_HUMAN-Phosphoserine24 relationship: location_of CCO:B0067010 ! IF2M_HUMAN-Phosphothreonine688 relationship: location_of CCO:B0067059 ! IFIH1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0067140 ! IQEC1_HUMAN-Phosphoserine515 relationship: location_of CCO:B0067141 ! IQEC2_HUMAN-Phosphoserine82 relationship: location_of CCO:B0067150 ! IQGA3_HUMAN-Phosphoserine1424 relationship: location_of CCO:B0067179 ! JAD1A_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0067186 ! JAD1C_HUMAN-Phosphoserine317 relationship: location_of CCO:B0067209 ! JHD2C_HUMAN-Phosphoserine373 relationship: location_of CCO:B0067234 ! K1219_HUMAN-Phosphoserine720 relationship: location_of CCO:B0067238 ! K1688_HUMAN-Phosphoserine406 relationship: location_of CCO:B0067250 ! KAISO_HUMAN-Phosphotyrosine442 relationship: location_of CCO:B0067251 ! KALRN_HUMAN-Phosphoserine1750 relationship: location_of CCO:B0067359 ! KIF22_HUMAN-Phosphoserine412 relationship: location_of CCO:B0067370 ! KKCC2_HUMAN-Phosphoserine133 relationship: location_of CCO:B0067372 ! KLF10_HUMAN-Phosphoserine249 relationship: location_of CCO:B0067381 ! KLF3_HUMAN-Phosphoserine92 relationship: location_of CCO:B0067407 ! KPCD2_HUMAN-Phosphoserine876 relationship: location_of CCO:B0067440 ! KRBA2_HUMAN-Phosphoserine115 relationship: location_of CCO:B0067499 ! KSR1_HUMAN-Phosphoserine567 relationship: location_of CCO:B0068055 ! MCF2_HUMAN-Phosphoserine742 relationship: location_of CCO:B0068200 ! MIST_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0068256 ! MPIP3_HUMAN-Phosphoserine57 relationship: location_of CCO:B0068321 ! MTPN_HUMAN-N-acetylcysteine2 relationship: location_of CCO:B0068448 ! NC2B_HUMAN-Phosphoserine105 relationship: location_of CCO:B0068559 ! NED4L_HUMAN-Phosphoserine449 relationship: location_of CCO:B0068635 ! NFIA_HUMAN-Phosphoserine258 relationship: location_of CCO:B0068644 ! NFIB_HUMAN-Phosphoserine292 relationship: location_of CCO:B0068653 ! NFIC_HUMAN-Phosphoserine339 relationship: location_of CCO:B0068704 ! NGEF_HUMAN-Phosphotyrosine179 relationship: location_of CCO:B0068796 ! NOSTN_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0069002 ! OSTF1_HUMAN-Phosphoserine202 relationship: location_of CCO:B0069034 ! P85A_HUMAN-Phosphotyrosine467 relationship: location_of CCO:B0069040 ! P85B_HUMAN-Phosphotyrosine467 relationship: location_of CCO:B0069107 ! PARF_HUMAN-Phosphoserine471 relationship: location_of CCO:B0069236 ! PESC_HUMAN-Phosphotyrosine548 relationship: location_of CCO:B0069343 ! PKHG1_HUMAN-Phosphoserine1245 relationship: location_of CCO:B0069345 ! PKHG2_HUMAN-Phosphoserine450 relationship: location_of CCO:B0069348 ! PKHG3_HUMAN-Phosphoserine640 relationship: location_of CCO:B0069354 ! PKHG4_HUMAN-Phosphoserine64 relationship: location_of CCO:B0069357 ! PKHG5_HUMAN-Phosphoserine959 relationship: location_of CCO:B0069421 ! PLXA1_HUMAN-Phosphotyrosine122 relationship: location_of CCO:B0069422 ! PLXA2_HUMAN-Phosphoserine1645 relationship: location_of CCO:B0069425 ! PLXA3_HUMAN-Phosphoserine1610 relationship: location_of CCO:B0069487 ! PRD10_HUMAN-Phosphoserine338 relationship: location_of CCO:B0069491 ! PRDM2_HUMAN-Phosphoserine643 relationship: location_of CCO:B0069526 ! PRKRA_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069566 ! PSD3_HUMAN-Phosphoserine1011 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0069671 ! RAB18_HUMAN-Phosphothreonine29 relationship: location_of CCO:B0069702 ! RAC2_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0069705 ! RAC3_HUMAN-Cysteine methyl ester189 relationship: location_of CCO:B0069748 ! RASA3_HUMAN-Phosphoserine809 relationship: location_of CCO:B0069749 ! RASD1_HUMAN-S-nitrosocysteine11 relationship: location_of CCO:B0069761 ! RB39B_HUMAN-Cysteine methyl ester213 relationship: location_of CCO:B0069772 ! RBG1L_HUMAN-Phosphoserine118 relationship: location_of CCO:B0069831 ! RBP1_HUMAN-Phosphoserine93 relationship: location_of CCO:B0069877 ! REQU_HUMAN-Phosphothreonine176 relationship: location_of CCO:B0069906 ! RGAP1_HUMAN-Phosphoserine600 relationship: location_of CCO:B0069908 ! RGF1B_HUMAN-Phosphotyrosine77 relationship: location_of CCO:B0069910 ! RGL2_HUMAN-Phosphoserine13 relationship: location_of CCO:B0069916 ! RGL3_HUMAN-Phosphoserine573 relationship: location_of CCO:B0069921 ! RGRF2_HUMAN-Phosphoserine737 relationship: location_of CCO:B0069929 ! RHG01_HUMAN-Phosphotyrosine65 relationship: location_of CCO:B0069930 ! RHG04_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0069933 ! RHG05_HUMAN-Phosphoserine1124 relationship: location_of CCO:B0069944 ! RHG06_HUMAN-Phosphoserine754 relationship: location_of CCO:B0069955 ! RHG19_HUMAN-Phosphoserine422 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0069975 ! RHG23_HUMAN-Phosphoserine372 relationship: location_of CCO:B0069983 ! RHG25_HUMAN-Phosphoserine400 relationship: location_of CCO:B0069988 ! RHG29_HUMAN-Phosphoserine913 relationship: location_of CCO:B0069994 ! RHG30_HUMAN-Phosphoserine988 relationship: location_of CCO:B0070004 ! RHGBA_HUMAN-Phosphoserine422 relationship: location_of CCO:B0070012 ! RHOH_HUMAN-Cysteine methyl ester188 relationship: location_of CCO:B0070013 ! RHOJ_HUMAN-Cysteine methyl ester211 relationship: location_of CCO:B0070014 ! RHOQ_HUMAN-Cysteine methyl ester202 relationship: location_of CCO:B0070015 ! RHPN2_HUMAN-Nitrated tyrosine258 relationship: location_of CCO:B0070017 ! RICH2_HUMAN-Phosphoserine514 relationship: location_of CCO:B0070063 ! RL14_HUMAN-Phosphoserine139 relationship: location_of CCO:B0070068 ! RL1D1_HUMAN-Phosphothreonine358 relationship: location_of CCO:B0070079 ! RL26_HUMAN-Phosphothreonine139 relationship: location_of CCO:B0070080 ! RL29_HUMAN-N6-methyllysine5 relationship: location_of CCO:B0070084 ! RL31_HUMAN-Phosphotyrosine108 relationship: location_of CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 relationship: location_of CCO:B0070091 ! RLF_HUMAN-Phosphoserine41 relationship: location_of CCO:B0070132 ! ROCK1_HUMAN-Phosphothreonine1180 relationship: location_of CCO:B0070172 ! RPGF6_HUMAN-Phosphothreonine1507 relationship: location_of CCO:B0070190 ! RREB1_HUMAN-Phosphothreonine1315 relationship: location_of CCO:B0070197 ! RRP5_HUMAN-Phosphoserine1360 relationship: location_of CCO:B0070200 ! RS11_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 relationship: location_of CCO:B0070222 ! RS8_HUMAN-Phosphothreonine130 relationship: location_of CCO:B0070249 ! RSLAB_HUMAN-Cysteine methyl ester200 relationship: location_of CCO:B0070251 ! RT09_HUMAN-Phosphotyrosine262 relationship: location_of CCO:B0070256 ! RTKN_HUMAN-Phosphoserine543 relationship: location_of CCO:B0070270 ! RYBP_HUMAN-Phosphoserine130 relationship: location_of CCO:B0070312 ! SALL1_HUMAN-Phosphoserine586 relationship: location_of CCO:B0070314 ! SALL2_HUMAN-Phosphothreonine616 relationship: location_of CCO:B0070401 ! SFR14_HUMAN-Phosphoserine315 relationship: location_of CCO:B0070461 ! SH23A_HUMAN-Phosphoserine125 relationship: location_of CCO:B0070472 ! SH2D3_HUMAN-Phosphotyrosine283 relationship: location_of CCO:B0070528 ! SI1L2_HUMAN-Phosphoserine1029 relationship: location_of CCO:B0070531 ! SI1L3_HUMAN-Phosphotyrosine1265 relationship: location_of CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0070598 ! SMAD2_HUMAN-Phosphoserine255 relationship: location_of CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 relationship: location_of CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 relationship: location_of CCO:B0070720 ! SOLO_HUMAN-Phosphoserine931 relationship: location_of CCO:B0070734 ! SON_HUMAN-Phosphoserine1784 relationship: location_of CCO:B0070746 ! SOS1_HUMAN-Phosphoserine1134 relationship: location_of CCO:B0070783 ! SP3_HUMAN-Phosphoserine566 relationship: location_of CCO:B0070916 ! SRGP1_HUMAN-Phosphothreonine1001 relationship: location_of CCO:B0070923 ! SRGP2_HUMAN-Phosphoserine602 relationship: location_of CCO:B0071028 ! SYDE1_HUMAN-Phosphothreonine246 relationship: location_of CCO:B0071075 ! TAB2_HUMAN-Phosphoserine372 relationship: location_of CCO:B0071078 ! TAB3_HUMAN-Phosphoserine408 relationship: location_of CCO:B0071167 ! TB10A_HUMAN-Phosphoserine407 relationship: location_of CCO:B0071173 ! TB10B_HUMAN-Phosphothreonine434 relationship: location_of CCO:B0071212 ! TBC15_HUMAN-Phosphotyrosine215 relationship: location_of CCO:B0071215 ! TBC19_HUMAN-Phosphotyrosine25 relationship: location_of CCO:B0071217 ! TBC23_HUMAN-Phosphoserine507 relationship: location_of CCO:B0071219 ! TBC25_HUMAN-Phosphoserine506 relationship: location_of CCO:B0071220 ! TBC9B_HUMAN-Phosphoserine411 relationship: location_of CCO:B0071227 ! TBCD5_HUMAN-Phosphoserine43 relationship: location_of CCO:B0071235 ! TBCD9_HUMAN-Phosphoserine997 relationship: location_of CCO:B0071236 ! TBD2A_HUMAN-Phosphothreonine186 relationship: location_of CCO:B0071243 ! TBD2B_HUMAN-Phosphoserine957 relationship: location_of CCO:B0071286 ! TCGAP_HUMAN-Phosphotyrosine1169 relationship: location_of CCO:B0071337 ! TENX_HUMAN-Phosphotyrosine1417 relationship: location_of CCO:B0071396 ! TIAM1_HUMAN-Phosphoserine231 relationship: location_of CCO:B0071447 ! TOM1_HUMAN-Phosphoserine176 relationship: location_of CCO:B0071531 ! TRBP2_HUMAN-Phosphoserine152 relationship: location_of CCO:B0071532 ! TREF1_HUMAN-Phosphoserine491 relationship: location_of CCO:B0071551 ! TRI29_HUMAN-Phosphoserine21 relationship: location_of CCO:B0071561 ! TRI41_HUMAN-Phosphoserine447 relationship: location_of CCO:B0071574 ! TRIPC_HUMAN-Phosphoserine997 relationship: location_of CCO:B0071586 ! TRPS1_HUMAN-Phosphoserine127 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: location_of CCO:B0071607 ! TSH3_HUMAN-Phosphoserine672 relationship: location_of CCO:B0071709 ! UC5IP_HUMAN-Phosphoserine16 relationship: location_of CCO:B0071741 ! US6NL_HUMAN-Phosphoserine391 relationship: location_of CCO:B0071789 ! VAV2_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0071790 ! VAV_HUMAN-Phosphotyrosine826 relationship: location_of CCO:B0071823 ! WASF2_HUMAN-Phosphoserine482 relationship: location_of CCO:B0071883 ! WWP2_HUMAN-Phosphoserine211 relationship: location_of CCO:B0071902 ! YAF2_HUMAN-Phosphoserine167 relationship: location_of CCO:B0071931 ! Z280B_HUMAN-Phosphoserine105 relationship: location_of CCO:B0071936 ! Z280C_HUMAN-Phosphothreonine540 relationship: location_of CCO:B0071945 ! Z585A_HUMAN-Phosphoserine118 relationship: location_of CCO:B0071955 ! ZBT10_HUMAN-Phosphoserine565 relationship: location_of CCO:B0071958 ! ZBT12_HUMAN-Phosphothreonine19 relationship: location_of CCO:B0071969 ! ZBT40_HUMAN-Phosphothreonine412 relationship: location_of CCO:B0071975 ! ZBT44_HUMAN-Phosphoserine194 relationship: location_of CCO:B0071977 ! ZBT7A_HUMAN-Phosphoserine341 relationship: location_of CCO:B0071980 ! ZBT7C_HUMAN-Phosphotyrosine331 relationship: location_of CCO:B0071991 ! ZEB1_HUMAN-Phosphoserine679 relationship: location_of CCO:B0071994 ! ZEP1_HUMAN-Phosphoserine1874 relationship: location_of CCO:B0071996 ! ZEP2_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0072004 ! ZF106_HUMAN-Phosphoserine1026 relationship: location_of CCO:B0072012 ! ZFHX3_HUMAN-Phosphoserine1180 relationship: location_of CCO:B0072016 ! ZFHX4_HUMAN-Phosphoserine1892 relationship: location_of CCO:B0072021 ! ZFP91_HUMAN-Phosphothreonine395 relationship: location_of CCO:B0072035 ! ZHX3_HUMAN-Phosphoserine680 relationship: location_of CCO:B0072038 ! ZKSC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0072042 ! ZKSC2_HUMAN-Phosphoserine600 relationship: location_of CCO:B0072043 ! ZKSC4_HUMAN-Phosphoserine165 relationship: location_of CCO:B0072048 ! ZN101_HUMAN-Phosphoserine433 relationship: location_of CCO:B0072049 ! ZN142_HUMAN-Phosphoserine1319 relationship: location_of CCO:B0072053 ! ZN148_HUMAN-Phosphoserine306 relationship: location_of CCO:B0072056 ! ZN160_HUMAN-Phosphothreonine588 relationship: location_of CCO:B0072058 ! ZN174_HUMAN-Phosphotyrosine382 relationship: location_of CCO:B0072059 ! ZN180_HUMAN-Phosphoserine68 relationship: location_of CCO:B0072064 ! ZN217_HUMAN-Phosphoserine407 relationship: location_of CCO:B0072068 ! ZN219_HUMAN-Phosphoserine175 relationship: location_of CCO:B0072069 ! ZN224_HUMAN-Phosphoserine245 relationship: location_of CCO:B0072070 ! ZN225_HUMAN-Phosphothreonine283 relationship: location_of CCO:B0072071 ! ZN238_HUMAN-Phosphoserine516 relationship: location_of CCO:B0072073 ! ZN239_HUMAN-Phosphoserine41 relationship: location_of CCO:B0072078 ! ZN264_HUMAN-Phosphotyrosine483 relationship: location_of CCO:B0072083 ! ZN276_HUMAN-Phosphoserine93 relationship: location_of CCO:B0072087 ! ZN281_HUMAN-Phosphoserine484 relationship: location_of CCO:B0072103 ! ZN318_HUMAN-Phosphoserine1896 relationship: location_of CCO:B0072114 ! ZN335_HUMAN-Phosphoserine1153 relationship: location_of CCO:B0072119 ! ZN391_HUMAN-Phosphothreonine49 relationship: location_of CCO:B0072124 ! ZN423_HUMAN-Phosphoserine608 relationship: location_of CCO:B0072125 ! ZN432_HUMAN-Nitrated tyrosine41 relationship: location_of CCO:B0072127 ! ZN444_HUMAN-Phosphoserine235 relationship: location_of CCO:B0072137 ! ZN496_HUMAN-Phosphoserine185 relationship: location_of CCO:B0072146 ! ZN532_HUMAN-Phosphoserine268 relationship: location_of CCO:B0072165 ! ZN592_HUMAN-Phosphoserine146 relationship: location_of CCO:B0072177 ! ZN600_HUMAN-Phosphoserine116 relationship: location_of CCO:B0072182 ! ZN609_HUMAN-Phosphoserine846 relationship: location_of CCO:B0072185 ! ZN618_HUMAN-Phosphoserine16 relationship: location_of CCO:B0072196 ! ZN638_HUMAN-Phosphoserine605 relationship: location_of CCO:B0072201 ! ZN639_HUMAN-Phosphotyrosine4 relationship: location_of CCO:B0072204 ! ZN644_HUMAN-Phosphoserine1189 relationship: location_of CCO:B0072207 ! ZN652_HUMAN-Phosphoserine380 relationship: location_of CCO:B0072209 ! ZN654_HUMAN-Phosphoserine580 relationship: location_of CCO:B0072210 ! ZN665_HUMAN-Phosphotyrosine97 relationship: location_of CCO:B0072218 ! ZN687_HUMAN-Phosphothreonine900 relationship: location_of CCO:B0072227 ! ZN717_HUMAN-Phosphoserine391 relationship: location_of CCO:B0072233 ! ZN768_HUMAN-Phosphoserine18 relationship: location_of CCO:B0072239 ! ZN775_HUMAN-Phosphothreonine304 relationship: location_of CCO:B0072245 ! ZN787_HUMAN-Phosphoserine171 relationship: location_of CCO:B0072247 ! ZN800_HUMAN-Phosphoserine317 relationship: location_of CCO:B0072255 ! ZN846_HUMAN-Phosphoserine98 relationship: location_of CCO:B0072256 ! ZNF44_HUMAN-Phosphoserine427 relationship: location_of CCO:B0072258 ! ZNF8_HUMAN-Phosphoserine455 relationship: location_of CCO:B0072280 ! ZXDA_HUMAN-Phosphoserine34 [Term] id: CCO:C0000243 name: cell namespace: cellular_component def: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:go_curators] subset: goslim_generic subset: goslim_goa subset: goslim_plant subset: gosubset_prok xref: GO:0005623 is_a: CCO:C0000200 ! cellular_component relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0058800 ! CAN10_HUMAN relationship: location_of CCO:B0068816 ! NPY_HUMAN-Tyrosine amide64 [Term] id: CCO:C0000244 name: membrane fraction namespace: cellular_component def: "That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes." [GOC:ma] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. subset: goslim_candida subset: goslim_yeast subset: gosubset_prok xref: GO:0005624 is_a: CCO:C0000246 ! insoluble fraction relationship: location_of CCO:B0001455 ! RECK_HUMAN relationship: location_of CCO:B0001466 ! RASN_HUMAN relationship: location_of CCO:B0001737 ! STRN3_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0002078 ! PMYT1_HUMAN relationship: location_of CCO:B0005422 ! BID_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005761 ! RL7A_HUMAN relationship: location_of CCO:B0005868 ! FGFR1_HUMAN relationship: location_of CCO:B0005875 ! CD59_HUMAN relationship: location_of CCO:B0005981 ! TRI27_HUMAN relationship: location_of CCO:B0006166 ! KIF5A_HUMAN relationship: location_of CCO:B0006179 ! APLP1_HUMAN relationship: location_of CCO:B0006198 ! CENPR_HUMAN relationship: location_of CCO:B0006350 ! VAMP8_HUMAN relationship: location_of CCO:B0010481 ! AIP_HUMAN-Phosphotyrosine248 relationship: location_of CCO:B0010637 ! AT1A1_HUMAN-Phosphothreonine219 relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0010760 ! BCAR1_HUMAN-Phosphotyrosine362 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0012627 ! KPCA_HUMAN-Phosphoserine657 relationship: location_of CCO:B0012636 ! KPCZ_HUMAN-Phosphothreonine560 relationship: location_of CCO:B0012651 ! KU70_HUMAN-Phosphoserine51 relationship: location_of CCO:B0012916 ! MET_HUMAN-Phosphotyrosine1356 relationship: location_of CCO:B0013468 ! PDLI5_HUMAN-Phosphoserine136 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0013716 ! RASK_HUMAN-ester186 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0014729 ! YES_HUMAN-Phosphotyrosine426 relationship: location_of CCO:B0015682 ! EI2BA_HUMAN relationship: location_of CCO:B0018486 ! CLTR1_HUMAN relationship: location_of CCO:B0018655 ! RYK_HUMAN relationship: location_of CCO:B0018761 ! M3K13_HUMAN relationship: location_of CCO:B0018778 ! M3K12_HUMAN relationship: location_of CCO:B0022455 ! KAP2_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0025070 ! PDZD3_HUMAN relationship: location_of CCO:B0029727 ! CEAM1_HUMAN relationship: location_of CCO:B0034291 ! IGHG3_HUMAN relationship: location_of CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035557 ! RGS19_HUMAN-Phosphoserine24 relationship: location_of CCO:B0035712 ! STMN2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0039654 ! SPHK2_HUMAN-Phosphoserine399 relationship: location_of CCO:B0039811 ! BIRC6_HUMAN relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0050753 ! OPRD_HUMAN relationship: location_of CCO:B0050755 ! SSR2_HUMAN relationship: location_of CCO:B0050788 ! SSR1_HUMAN relationship: location_of CCO:B0051370 ! FIBP_HUMAN relationship: location_of CCO:B0051475 ! MOT3_HUMAN relationship: location_of CCO:B0052399 ! GBRL2_HUMAN-Phosphoserine10 relationship: location_of CCO:B0052705 ! ROS_HUMAN-Phosphotyrosine2114 relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054344 ! LPP1_HUMAN relationship: location_of CCO:B0054367 ! PTGES_HUMAN relationship: location_of CCO:B0054386 ! MGST3_HUMAN relationship: location_of CCO:B0054391 ! GIPC1_HUMAN relationship: location_of CCO:B0054485 ! AT8B1_HUMAN relationship: location_of CCO:B0054516 ! CYH3_HUMAN relationship: location_of CCO:B0054556 ! FADS1_HUMAN relationship: location_of CCO:B0054589 ! NSMA_HUMAN relationship: location_of CCO:B0054666 ! RHBL1_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054757 ! RPGF3_HUMAN relationship: location_of CCO:B0054765 ! GNAS3_HUMAN relationship: location_of CCO:B0054929 ! ADRB1_HUMAN relationship: location_of CCO:B0054941 ! DOPO_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0054946 ! CD7_HUMAN relationship: location_of CCO:B0055006 ! ACE_HUMAN relationship: location_of CCO:B0055086 ! ANPRC_HUMAN relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0055207 ! CD38_HUMAN relationship: location_of CCO:B0055210 ! AA2AR_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055325 ! ADCY8_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0055400 ! T4S4_HUMAN relationship: location_of CCO:B0055483 ! NR0B1_HUMAN relationship: location_of CCO:B0055519 ! EMP1_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0055616 ! ARF6_HUMAN relationship: location_of CCO:B0055669 ! VLDLR_HUMAN relationship: location_of CCO:B0055740 ! PLP2_HUMAN relationship: location_of CCO:B0055851 ! CNTN1_HUMAN relationship: location_of CCO:B0055864 ! TSN31_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055912 ! MADCA_HUMAN relationship: location_of CCO:B0055937 ! 5HT4R_HUMAN relationship: location_of CCO:B0055942 ! ARFRP_HUMAN relationship: location_of CCO:B0056531 ! LRRK2_HUMAN relationship: location_of CCO:B0056727 ! MCTP1_HUMAN relationship: location_of CCO:B0056892 ! Q6P5Z4_HUMAN relationship: location_of CCO:B0056928 ! Q6QEF7_HUMAN relationship: location_of CCO:B0057459 ! LIRB2_HUMAN relationship: location_of CCO:B0057927 ! GRP4_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058055 ! RPGF4_HUMAN relationship: location_of CCO:B0058102 ! EDA_HUMAN relationship: location_of CCO:B0058294 ! KREM1_HUMAN relationship: location_of CCO:B0058410 ! CYH2_HUMAN relationship: location_of CCO:B0058450 ! MGST2_HUMAN relationship: location_of CCO:B0058705 ! TXND1_HUMAN relationship: location_of CCO:B0058706 ! HRH4_HUMAN relationship: location_of CCO:B0058780 ! NMUR1_HUMAN relationship: location_of CCO:B0058846 ! LT4R2_HUMAN relationship: location_of CCO:B0059015 ! BFAR_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059146 ! CLC2D_HUMAN relationship: location_of CCO:B0059150 ! RPGFL_HUMAN relationship: location_of CCO:B0059394 ! BACE2_HUMAN relationship: location_of CCO:B0062832 ! EAA3_HUMAN relationship: location_of CCO:B0062978 ! HPS1_HUMAN relationship: location_of CCO:B0062993 ! MDR1_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063449 ! STT3A_HUMAN relationship: location_of CCO:B0063615 ! ARRB1_HUMAN-Phosphothreonine410 relationship: location_of CCO:B0063685 ! AVEN_HUMAN-Phosphoserine94 relationship: location_of CCO:B0063924 ! BIM_HUMAN-Phosphoserine77 relationship: location_of CCO:B0064367 ! CKAP4_HUMAN-Phosphoserine312 relationship: location_of CCO:B0065046 ! EM55_HUMAN-Phosphoserine19 relationship: location_of CCO:B0065230 ! AAAT_HUMAN-Phosphoserine535 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0065565 ! AKP13_HUMAN-Phosphoserine1929 relationship: location_of CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 relationship: location_of CCO:B0066435 ! GDIA_HUMAN-Phosphotyrosine339 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0066894 ! HPS4_HUMAN-Phosphoserine355 relationship: location_of CCO:B0067425 ! KPCE_HUMAN-Phosphothreonine309 relationship: location_of CCO:B0067513 ! KTN1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0068055 ! MCF2_HUMAN-Phosphoserine742 relationship: location_of CCO:B0068070 ! MCTP2_HUMAN-Phosphoserine145 relationship: location_of CCO:B0068260 ! MPP2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0069171 ! PDE4A_HUMAN-Phosphoserine686 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0069702 ! RAC2_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0070676 ! SNAG_HUMAN-Phosphoserine284 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: location_of CCO:B0070798 ! SPHK1_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0070821 ! SPTA2_HUMAN-Phosphoserine1217 relationship: location_of CCO:B0070979 ! STRN4_HUMAN-Phosphoserine276 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: location_of CCO:B0071730 ! ULK1_HUMAN-Phosphothreonine625 relationship: location_of CCO:B0072004 ! ZF106_HUMAN-Phosphoserine1026 [Term] id: CCO:C0000245 name: soluble fraction namespace: cellular_component def: "That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water." [GOC:ma] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. synonym: "soluble" BROAD [] xref: GO:0005625 is_a: CCO:C0000046 ! cell fraction relationship: location_of CCO:B0001590 ! BTC_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0005479 ! TNR6_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005661 ! IPO7_HUMAN relationship: location_of CCO:B0005706 ! M4K2_HUMAN relationship: location_of CCO:B0005753 ! SYFB_HUMAN relationship: location_of CCO:B0005795 ! MED22_HUMAN relationship: location_of CCO:B0005959 ! FBLN1_HUMAN relationship: location_of CCO:B0005989 ! FBLN5_HUMAN relationship: location_of CCO:B0006143 ! GPDA_HUMAN relationship: location_of CCO:B0006239 ! RED_HUMAN relationship: location_of CCO:B0006263 ! GLHA_HUMAN relationship: location_of CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010440 ! ACTB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010556 ! ANXA2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0012175 ! HD_HUMAN-Phosphoserine421 relationship: location_of CCO:B0013374 ! PACA_HUMAN-Lysine amide169 relationship: location_of CCO:B0014274 ! SYK_HUMAN-Phosphoserine596 relationship: location_of CCO:B0014355 ! THRB_HUMAN-4-carboxyglutamate59 relationship: location_of CCO:B0014388 ! TKNK_HUMAN-Methionine amide90 relationship: location_of CCO:B0017509 ! FGF20_HUMAN relationship: location_of CCO:B0021692 ! WISP1_HUMAN relationship: location_of CCO:B0021699 ! WISP2_HUMAN relationship: location_of CCO:B0021811 ! SYWC_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0025635 ! PTPA_HUMAN relationship: location_of CCO:B0030742 ! IDE_HUMAN relationship: location_of CCO:B0032819 ! ASNS_HUMAN relationship: location_of CCO:B0032938 ! ANGT_HUMAN relationship: location_of CCO:B0034779 ! FABP4_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0035418 ! PPAC_HUMAN-Phosphotyrosine133 relationship: location_of CCO:B0035712 ! STMN2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: location_of CCO:B0039662 ! SYG_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0043823 ! EDN3_HUMAN relationship: location_of CCO:B0043869 ! U119A_HUMAN relationship: location_of CCO:B0048252 ! EFNB1_HUMAN-Phosphotyrosine317 relationship: location_of CCO:B0048872 ! ALS_HUMAN relationship: location_of CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054391 ! GIPC1_HUMAN relationship: location_of CCO:B0054436 ! CCL25_HUMAN relationship: location_of CCO:B0054701 ! TPPP_HUMAN relationship: location_of CCO:B0054719 ! UBR5_HUMAN relationship: location_of CCO:B0054755 ! WISP3_HUMAN relationship: location_of CCO:B0054760 ! TNR6B_HUMAN relationship: location_of CCO:B0054839 ! FSHB_HUMAN relationship: location_of CCO:B0054840 ! LSHB_HUMAN relationship: location_of CCO:B0054841 ! CGHB_HUMAN relationship: location_of CCO:B0054866 ! FIBB_HUMAN relationship: location_of CCO:B0054938 ! NMB_HUMAN relationship: location_of CCO:B0054941 ! DOPO_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0054948 ! GIP_HUMAN relationship: location_of CCO:B0054970 ! CALCB_HUMAN relationship: location_of CCO:B0054972 ! CCL3_HUMAN relationship: location_of CCO:B0055007 ! MOTI_HUMAN relationship: location_of CCO:B0055125 ! EDN2_HUMAN relationship: location_of CCO:B0055170 ! CRHBP_HUMAN relationship: location_of CCO:B0055180 ! ARBK1_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055232 ! NEUT_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055271 ! GRK5_HUMAN relationship: location_of CCO:B0055311 ! ARRC_HUMAN relationship: location_of CCO:B0055336 ! WNT5A_HUMAN relationship: location_of CCO:B0055405 ! GSH0_HUMAN relationship: location_of CCO:B0055435 ! FLT3L_HUMAN relationship: location_of CCO:B0055455 ! TNF10_HUMAN relationship: location_of CCO:B0055552 ! RP1_HUMAN relationship: location_of CCO:B0055725 ! ERCC6_HUMAN relationship: location_of CCO:B0055766 ! REG3A_HUMAN relationship: location_of CCO:B0055887 ! ERCC8_HUMAN relationship: location_of CCO:B0056006 ! INSL4_HUMAN relationship: location_of CCO:B0057927 ! GRP4_HUMAN relationship: location_of CCO:B0057945 ! CGAT1_HUMAN relationship: location_of CCO:B0057959 ! PP4R1_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058077 ! FAN_HUMAN relationship: location_of CCO:B0058415 ! STAC_HUMAN relationship: location_of CCO:B0058902 ! CYTL1_HUMAN relationship: location_of CCO:B0058912 ! FGF21_HUMAN relationship: location_of CCO:B0059031 ! IL17C_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059139 ! PCSK1_HUMAN relationship: location_of CCO:B0059296 ! TN13B_HUMAN relationship: location_of CCO:B0062978 ! HPS1_HUMAN relationship: location_of CCO:B0063045 ! SYIC_HUMAN relationship: location_of CCO:B0063058 ! SYRC_HUMAN relationship: location_of CCO:B0063160 ! COMT_HUMAN relationship: location_of CCO:B0063250 ! OS9_HUMAN relationship: location_of CCO:B0063332 ! SYNC_HUMAN relationship: location_of CCO:B0063370 ! SRC8_HUMAN relationship: location_of CCO:B0063445 ! BLMH_HUMAN relationship: location_of CCO:B0063615 ! ARRB1_HUMAN-Phosphothreonine410 relationship: location_of CCO:B0064123 ! CCR2_HUMAN-Sulfotyrosine26 relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064466 ! CRF_HUMAN-Isoleucine amide194 relationship: location_of CCO:B0064906 ! DUS6_HUMAN-Phosphoserine331 relationship: location_of CCO:B0065410 ! ADCYA_HUMAN-Phosphothreonine809 relationship: location_of CCO:B0065425 ! ADML_HUMAN-Tyrosine amide146 relationship: location_of CCO:B0066471 ! GLUC_HUMAN-Arginine amide127 relationship: location_of CCO:B0066513 ! GON1_HUMAN-Glycine amide33 relationship: location_of CCO:B0066515 ! GON2_HUMAN-Glycine amide33 relationship: location_of CCO:B0066639 ! GSUB_HUMAN-Phosphothreonine119 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066979 ! IAPP_HUMAN-Tyrosine amide70 relationship: location_of CCO:B0067794 ! LTK_HUMAN-Phosphotyrosine672 relationship: location_of CCO:B0068111 ! MDHC_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0068148 ! MERTK_HUMAN-Phosphotyrosine754 relationship: location_of CCO:B0068437 ! NAGK_HUMAN-Phosphotyrosine205 relationship: location_of CCO:B0068457 ! NCF1_HUMAN-Phosphoserine304 relationship: location_of CCO:B0068577 ! NEU2_HUMAN-Glycine amide28 relationship: location_of CCO:B0068813 ! NPFF_HUMAN-Phenylalanine amide76 relationship: location_of CCO:B0069171 ! PDE4A_HUMAN-Phosphoserine686 relationship: location_of CCO:B0069173 ! PDE4B_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0069178 ! PDE4D_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0069654 ! PYY_HUMAN-Phosphoserine41 relationship: location_of CCO:B0069749 ! RASD1_HUMAN-S-nitrosocysteine11 relationship: location_of CCO:B0069839 ! RCAS1_HUMAN-Phosphothreonine41 relationship: location_of CCO:B0070459 ! SH22A_HUMAN-Phosphoserine296 relationship: location_of CCO:B0070798 ! SPHK1_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0071022 ! SYAC_HUMAN-Phosphothreonine578 relationship: location_of CCO:B0071036 ! SYEP_HUMAN-Phosphoserine891 relationship: location_of CCO:B0071545 ! TRH_HUMAN-Proline amide154 [Term] id: CCO:C0000246 name: insoluble fraction namespace: cellular_component def: "That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water." [GOC:ma] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. synonym: "particle-bound" RELATED [] xref: GO:0005626 is_a: CCO:C0000046 ! cell fraction relationship: location_of CCO:B0001712 ! MDM2_HUMAN relationship: location_of CCO:B0001758 ! ULA1_HUMAN relationship: location_of CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: location_of CCO:B0024484 ! PLCB3_HUMAN relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0055526 ! BI1_HUMAN relationship: location_of CCO:B0059050 ! DAPLE_HUMAN relationship: location_of CCO:B0069171 ! PDE4A_HUMAN-Phosphoserine686 relationship: location_of CCO:B0069173 ! PDE4B_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0069178 ! PDE4D_HUMAN-Phosphoserine18 [Term] id: CCO:C0000247 name: prospore membrane namespace: cellular_component def: "The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls." [ISBN:0879693649] subset: gosubset_prok synonym: "forespore membrane (sensu Fungi)" EXACT [] synonym: "FSM" EXACT [] xref: GO:0005628 is_a: CCO:C0000766 ! membrane relationship: part_of CCO:C0002135 ! ascospore-type prospore [Term] id: CCO:C0000248 name: dityrosine layer of spore wall namespace: cellular_component def: "The outermost layer of the spore wall, as described in Saccharomyces." [ISBN:0879693568] xref: GO:0005630 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0002065 ! fungal-type spore wall [Term] id: CCO:C0000249 name: chitosan layer of spore wall namespace: cellular_component def: "The second outermost layer of the spore wall, as described in Saccharomyces." [ISBN:0879693568] xref: GO:0005631 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0002065 ! fungal-type spore wall [Term] id: CCO:C0000250 name: inner layer of spore wall namespace: cellular_component def: "Either of the two innermost layers of the spore wall, as described in Saccharomyces." [ISBN:0879693568] xref: GO:0005632 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0002065 ! fungal-type spore wall [Term] id: CCO:C0000251 name: ascus lipid droplet namespace: cellular_component def: "Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins." [GOC:mah, PMID:12702293] xref: GO:0005633 is_a: CCO:C0000382 ! lipid particle [Term] id: CCO:C0000252 name: nucleus namespace: cellular_component def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell nucleus" EXACT [] xref: GO:0005634 is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0001317 ! E2F8_HUMAN relationship: location_of CCO:B0001333 ! A6NK88_HUMAN relationship: location_of CCO:B0001341 ! A6NMP7_HUMAN relationship: location_of CCO:B0001343 ! A7KMP4_HUMAN relationship: location_of CCO:B0001344 ! APBB1_HUMAN relationship: location_of CCO:B0001346 ! CDC7_HUMAN relationship: location_of CCO:B0001352 ! E2F3_HUMAN relationship: location_of CCO:B0001355 ! CDKA1_HUMAN relationship: location_of CCO:B0001358 ! OVOL1_HUMAN relationship: location_of CCO:B0001366 ! MDM4_HUMAN relationship: location_of CCO:B0001367 ! AXN1_HUMAN relationship: location_of CCO:B0001370 ! FANCG_HUMAN relationship: location_of CCO:B0001372 ! PPM1D_HUMAN relationship: location_of CCO:B0001373 ! RA51B_HUMAN relationship: location_of CCO:B0001376 ! HDAC3_HUMAN relationship: location_of CCO:B0001378 ! MSH4_HUMAN relationship: location_of CCO:B0001379 ! FGF10_HUMAN relationship: location_of CCO:B0001382 ! SEPT4_HUMAN relationship: location_of CCO:B0001384 ! SIAH2_HUMAN relationship: location_of CCO:B0001391 ! SUV91_HUMAN relationship: location_of CCO:B0001395 ! BUB1_HUMAN relationship: location_of CCO:B0001396 ! BUB3_HUMAN relationship: location_of CCO:B0001397 ! ACTN4_HUMAN relationship: location_of CCO:B0001403 ! RAD21_HUMAN relationship: location_of CCO:B0001407 ! HBP1_HUMAN relationship: location_of CCO:B0001408 ! EVI5_HUMAN relationship: location_of CCO:B0001410 ! CCNT1_HUMAN relationship: location_of CCO:B0001413 ! RAD1_HUMAN relationship: location_of CCO:B0001419 ! HUS1_HUMAN relationship: location_of CCO:B0001426 ! CC45L_HUMAN relationship: location_of CCO:B0001429 ! E2F6_HUMAN relationship: location_of CCO:B0001431 ! SUPT3_HUMAN relationship: location_of CCO:B0001433 ! TAD3L_HUMAN relationship: location_of CCO:B0001434 ! RA51D_HUMAN relationship: location_of CCO:B0001442 ! RECQ4_HUMAN relationship: location_of CCO:B0001446 ! CCNB2_HUMAN relationship: location_of CCO:B0001447 ! REC8_HUMAN relationship: location_of CCO:B0001449 ! ZWINT_HUMAN relationship: location_of CCO:B0001450 ! SMC2_HUMAN relationship: location_of CCO:B0001451 ! YETS4_HUMAN relationship: location_of CCO:B0001457 ! PTTG1_HUMAN relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0001459 ! CHK2_HUMAN relationship: location_of CCO:B0001465 ! MYC_HUMAN relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0001481 ! HSP1_HUMAN relationship: location_of CCO:B0001482 ! PRM2_HUMAN relationship: location_of CCO:B0001494 ! S10A6_HUMAN relationship: location_of CCO:B0001510 ! IRF1_HUMAN relationship: location_of CCO:B0001513 ! PCNA_HUMAN relationship: location_of CCO:B0001519 ! CCNB1_HUMAN relationship: location_of CCO:B0001522 ! FOSL1_HUMAN relationship: location_of CCO:B0001524 ! NDKA_HUMAN relationship: location_of CCO:B0001526 ! H2AX_HUMAN relationship: location_of CCO:B0001536 ! WT1_HUMAN relationship: location_of CCO:B0001538 ! CCNA2_HUMAN relationship: location_of CCO:B0001539 ! PTMS_HUMAN relationship: location_of CCO:B0001543 ! TAF1_HUMAN relationship: location_of CCO:B0001546 ! NDKB_HUMAN relationship: location_of CCO:B0001552 ! GA45A_HUMAN relationship: location_of CCO:B0001553 ! CCNC_HUMAN relationship: location_of CCO:B0001562 ! RFA1_HUMAN relationship: location_of CCO:B0001564 ! DPOD1_HUMAN relationship: location_of CCO:B0001565 ! MK01_HUMAN relationship: location_of CCO:B0001573 ! CCND2_HUMAN relationship: location_of CCO:B0001574 ! CCND3_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0001585 ! TF2H1_HUMAN relationship: location_of CCO:B0001588 ! MCM5_HUMAN relationship: location_of CCO:B0001589 ! MCM7_HUMAN relationship: location_of CCO:B0001591 ! PHB_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0001594 ! DDIT3_HUMAN relationship: location_of CCO:B0001595 ! AHR_HUMAN relationship: location_of CCO:B0001598 ! BRCA1_HUMAN relationship: location_of CCO:B0001599 ! CDN1A_HUMAN relationship: location_of CCO:B0001600 ! VHL_HUMAN relationship: location_of CCO:B0001602 ! CCNF_HUMAN relationship: location_of CCO:B0001603 ! BCL6_HUMAN relationship: location_of CCO:B0001608 ! STAT1_HUMAN relationship: location_of CCO:B0001614 ! CNDD3_HUMAN relationship: location_of CCO:B0001615 ! CD2A1_HUMAN relationship: location_of CCO:B0001617 ! CDN2C_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001621 ! RAD52_HUMAN relationship: location_of CCO:B0001627 ! CDK8_HUMAN relationship: location_of CCO:B0001630 ! CTCF_HUMAN relationship: location_of CCO:B0001632 ! CLK1_HUMAN relationship: location_of CCO:B0001646 ! RASF2_HUMAN relationship: location_of CCO:B0001647 ! CDK9_HUMAN relationship: location_of CCO:B0001649 ! BRCA2_HUMAN relationship: location_of CCO:B0001653 ! MAT1_HUMAN relationship: location_of CCO:B0001655 ! NEK4_HUMAN relationship: location_of CCO:B0001656 ! CCNG1_HUMAN relationship: location_of CCO:B0001662 ! PPP5_HUMAN relationship: location_of CCO:B0001664 ! FOSB_HUMAN relationship: location_of CCO:B0001668 ! PMS1_HUMAN relationship: location_of CCO:B0001673 ! AIF1_HUMAN relationship: location_of CCO:B0001675 ! CDN2D_HUMAN relationship: location_of CCO:B0001676 ! NH2L1_HUMAN relationship: location_of CCO:B0001681 ! SESN2_HUMAN relationship: location_of CCO:B0001682 ! SESN3_HUMAN relationship: location_of CCO:B0001684 ! MLF1_HUMAN relationship: location_of CCO:B0001692 ! RHOB_HUMAN relationship: location_of CCO:B0001696 ! UBC9_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0001701 ! CCNA1_HUMAN relationship: location_of CCO:B0001708 ! CDK6_HUMAN relationship: location_of CCO:B0001712 ! MDM2_HUMAN relationship: location_of CCO:B0001717 ! ID3_HUMAN relationship: location_of CCO:B0001719 ! NOTC2_HUMAN relationship: location_of CCO:B0001721 ! RAD51_HUMAN relationship: location_of CCO:B0001727 ! RBBP4_HUMAN relationship: location_of CCO:B0001728 ! EP300_HUMAN relationship: location_of CCO:B0001732 ! SNF5_HUMAN relationship: location_of CCO:B0001737 ! STRN3_HUMAN relationship: location_of CCO:B0001741 ! ZBT17_HUMAN relationship: location_of CCO:B0001744 ! DUS4_HUMAN relationship: location_of CCO:B0001748 ! MD2L1_HUMAN relationship: location_of CCO:B0001752 ! UB2V1_HUMAN relationship: location_of CCO:B0001753 ! TOP3A_HUMAN relationship: location_of CCO:B0001756 ! ATR_HUMAN relationship: location_of CCO:B0001770 ! NFYC_HUMAN relationship: location_of CCO:B0001774 ! TOB2_HUMAN relationship: location_of CCO:B0001776 ! TFDP1_HUMAN relationship: location_of CCO:B0001777 ! TFDP2_HUMAN relationship: location_of CCO:B0001781 ! E2F2_HUMAN relationship: location_of CCO:B0001783 ! HIC1_HUMAN relationship: location_of CCO:B0001784 ! DMC1_HUMAN relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0001804 ! E2F5_HUMAN relationship: location_of CCO:B0001806 ! DHC24_HUMAN relationship: location_of CCO:B0001813 ! UB2V2_HUMAN relationship: location_of CCO:B0001817 ! E2F4_HUMAN relationship: location_of CCO:B0001831 ! Q3LRW5_HUMAN relationship: location_of CCO:B0001832 ! TBRG1_HUMAN relationship: location_of CCO:B0001833 ! Q499G5_HUMAN relationship: location_of CCO:B0001838 ! PKHO1_HUMAN relationship: location_of CCO:B0001847 ! SGOL1_HUMAN relationship: location_of CCO:B0001849 ! TFDP3_HUMAN relationship: location_of CCO:B0001854 ! Q5JSB5_HUMAN relationship: location_of CCO:B0001855 ! Q5JSB6_HUMAN relationship: location_of CCO:B0001861 ! SPDYC_HUMAN relationship: location_of CCO:B0001862 ! SPDYA_HUMAN relationship: location_of CCO:B0001872 ! Q5T317_HUMAN relationship: location_of CCO:B0001882 ! UT14C_HUMAN relationship: location_of CCO:B0001896 ! Q5TZP9_HUMAN relationship: location_of CCO:B0001902 ! POLS_HUMAN relationship: location_of CCO:B0001911 ! CDC73_HUMAN relationship: location_of CCO:B0001912 ! PMF1_HUMAN relationship: location_of CCO:B0001915 ! SYCE2_HUMAN relationship: location_of CCO:B0001916 ! DCR1A_HUMAN relationship: location_of CCO:B0001917 ! Q6Q9Z6_HUMAN relationship: location_of CCO:B0001923 ! Q6ZNA8_HUMAN relationship: location_of CCO:B0001926 ! Q6ZV00_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0001935 ! Q7Z774_HUMAN relationship: location_of CCO:B0001936 ! NPM2_HUMAN relationship: location_of CCO:B0001942 ! HORM1_HUMAN relationship: location_of CCO:B0001946 ! SIAH1_HUMAN relationship: location_of CCO:B0001955 ! CCRK_HUMAN relationship: location_of CCO:B0001957 ! SYCP3_HUMAN relationship: location_of CCO:B0001959 ! TAF1L_HUMAN relationship: location_of CCO:B0001960 ! SYCE1_HUMAN relationship: location_of CCO:B0001962 ! STAG2_HUMAN relationship: location_of CCO:B0001966 ! CD2A2_HUMAN relationship: location_of CCO:B0001971 ! BANP_HUMAN relationship: location_of CCO:B0001973 ! SPC24_HUMAN relationship: location_of CCO:B0001975 ! PAPD5_HUMAN relationship: location_of CCO:B0001976 ! RCBT1_HUMAN relationship: location_of CCO:B0001979 ! MNS1_HUMAN relationship: location_of CCO:B0001980 ! DP13B_HUMAN relationship: location_of CCO:B0001984 ! NEK11_HUMAN relationship: location_of CCO:B0001987 ! G45IP_HUMAN relationship: location_of CCO:B0001988 ! UHMK1_HUMAN relationship: location_of CCO:B0001989 ! UBA3_HUMAN relationship: location_of CCO:B0001995 ! RBCC1_HUMAN relationship: location_of CCO:B0001998 ! Q8TEY4_HUMAN relationship: location_of CCO:B0002001 ! Q8WUE3_HUMAN relationship: location_of CCO:B0002002 ! HDAC7_HUMAN relationship: location_of CCO:B0002007 ! CCNB3_HUMAN relationship: location_of CCO:B0002012 ! RSPH1_HUMAN relationship: location_of CCO:B0002016 ! RAD54_HUMAN relationship: location_of CCO:B0002017 ! DDX12_HUMAN relationship: location_of CCO:B0002018 ! SC65_HUMAN relationship: location_of CCO:B0002019 ! PCAF_HUMAN relationship: location_of CCO:B0002020 ! APBB2_HUMAN relationship: location_of CCO:B0002021 ! RAD50_HUMAN relationship: location_of CCO:B0002022 ! NGN1_HUMAN relationship: location_of CCO:B0002031 ! E2F7_HUMAN relationship: location_of CCO:B0002033 ! PINX1_HUMAN relationship: location_of CCO:B0002035 ! CHFR_HUMAN relationship: location_of CCO:B0002037 ! DDX11_HUMAN relationship: location_of CCO:B0002039 ! SIPA1_HUMAN relationship: location_of CCO:B0002041 ! SENP5_HUMAN relationship: location_of CCO:B0002048 ! Q96LE1_HUMAN relationship: location_of CCO:B0002056 ! MPPH1_HUMAN relationship: location_of CCO:B0002059 ! LAP2_HUMAN relationship: location_of CCO:B0002060 ! NEB2_HUMAN relationship: location_of CCO:B0002065 ! CDC5L_HUMAN relationship: location_of CCO:B0002070 ! ZWIA_HUMAN relationship: location_of CCO:B0002071 ! MPH6_HUMAN relationship: location_of CCO:B0002074 ! MNT_HUMAN relationship: location_of CCO:B0002075 ! NECD_HUMAN relationship: location_of CCO:B0002083 ! GFI1_HUMAN relationship: location_of CCO:B0002086 ! BARD1_HUMAN relationship: location_of CCO:B0002091 ! CITE2_HUMAN relationship: location_of CCO:B0002093 ! SPI2B_HUMAN relationship: location_of CCO:B0002095 ! 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ZN580_HUMAN relationship: location_of CCO:B0005231 ! ZBED1_HUMAN relationship: location_of CCO:B0005232 ! MDFI_HUMAN relationship: location_of CCO:B0005233 ! PSA1_HUMAN relationship: location_of CCO:B0005234 ! NONO_HUMAN relationship: location_of CCO:B0005251 ! SCNM1_HUMAN relationship: location_of CCO:B0005263 ! ZN567_HUMAN relationship: location_of CCO:B0005264 ! PHC1_HUMAN relationship: location_of CCO:B0005265 ! DYRK2_HUMAN relationship: location_of CCO:B0005268 ! ASF1A_HUMAN relationship: location_of CCO:B0005274 ! RHXF2_HUMAN relationship: location_of CCO:B0005276 ! ZN764_HUMAN relationship: location_of CCO:B0005277 ! MED4_HUMAN relationship: location_of CCO:B0005278 ! UBCP1_HUMAN relationship: location_of CCO:B0005281 ! M1IP1_HUMAN relationship: location_of CCO:B0005282 ! NOC4L_HUMAN relationship: location_of CCO:B0005283 ! TS101_HUMAN relationship: location_of CCO:B0005288 ! ARI2_HUMAN relationship: location_of CCO:B0005292 ! SPOP_HUMAN relationship: location_of CCO:B0005297 ! ZN263_HUMAN relationship: location_of CCO:B0005300 ! TAK1L_HUMAN relationship: location_of CCO:B0005301 ! MAF1_HUMAN relationship: location_of CCO:B0005302 ! CTDS1_HUMAN relationship: location_of CCO:B0005306 ! MYOZ1_HUMAN relationship: location_of CCO:B0005308 ! ZN451_HUMAN relationship: location_of CCO:B0005309 ! RNF37_HUMAN relationship: location_of CCO:B0005318 ! Q9BVJ0_HUMAN relationship: location_of CCO:B0005320 ! BATF_HUMAN relationship: location_of CCO:B0005321 ! PIAS2_HUMAN relationship: location_of CCO:B0005322 ! SMAD4_HUMAN relationship: location_of CCO:B0005323 ! FANCA_HUMAN relationship: location_of CCO:B0005324 ! CEBPG_HUMAN relationship: location_of CCO:B0005331 ! NEDD8_HUMAN relationship: location_of CCO:B0005332 ! FBX11_HUMAN relationship: location_of CCO:B0005340 ! PAX5_HUMAN relationship: location_of CCO:B0005341 ! HDA10_HUMAN relationship: location_of CCO:B0005342 ! DEK_HUMAN relationship: location_of CCO:B0005345 ! XPA_HUMAN relationship: location_of CCO:B0005346 ! SK2L2_HUMAN relationship: location_of CCO:B0005348 ! EXOSX_HUMAN relationship: location_of CCO:B0005349 ! LSM8_HUMAN relationship: location_of CCO:B0005350 ! TRRAP_HUMAN relationship: location_of CCO:B0005355 ! CAND1_HUMAN relationship: location_of CCO:B0005361 ! VPS72_HUMAN relationship: location_of CCO:B0005364 ! RUVB2_HUMAN relationship: location_of CCO:B0005368 ! ING3_HUMAN relationship: location_of CCO:B0005371 ! EPC2_HUMAN relationship: location_of CCO:B0005374 ! APLP2_HUMAN relationship: location_of CCO:B0005375 ! STK36_HUMAN relationship: location_of CCO:B0005382 ! NFYB_HUMAN relationship: location_of CCO:B0005384 ! NFYA_HUMAN relationship: location_of CCO:B0005389 ! ORC4_HUMAN relationship: location_of CCO:B0005390 ! ORC5_HUMAN relationship: location_of CCO:B0005391 ! MCM4_HUMAN relationship: location_of CCO:B0005396 ! TCRG1_HUMAN relationship: location_of CCO:B0005398 ! ELP1_HUMAN relationship: location_of CCO:B0005402 ! 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EXOS8_HUMAN relationship: location_of CCO:B0005561 ! T4AF1_HUMAN relationship: location_of CCO:B0005567 ! LSM6_HUMAN relationship: location_of CCO:B0005573 ! MED10_HUMAN relationship: location_of CCO:B0005574 ! MED29_HUMAN relationship: location_of CCO:B0005575 ! MED26_HUMAN relationship: location_of CCO:B0005578 ! ZN655_HUMAN relationship: location_of CCO:B0005587 ! TOP1_HUMAN relationship: location_of CCO:B0005593 ! CRNL1_HUMAN relationship: location_of CCO:B0005601 ! MYT1L_HUMAN relationship: location_of CCO:B0005607 ! MYT1_HUMAN relationship: location_of CCO:B0005613 ! SET1A_HUMAN relationship: location_of CCO:B0005614 ! ASH2L_HUMAN relationship: location_of CCO:B0005616 ! PPARG_HUMAN relationship: location_of CCO:B0005619 ! UBQL4_HUMAN relationship: location_of CCO:B0005621 ! P80C_HUMAN relationship: location_of CCO:B0005622 ! RPA12_HUMAN relationship: location_of CCO:B0005623 ! MEOX2_HUMAN relationship: location_of CCO:B0005630 ! ANM2_HUMAN relationship: location_of CCO:B0005632 ! MYB_HUMAN relationship: location_of CCO:B0005647 ! GCNL2_HUMAN relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0005661 ! IPO7_HUMAN relationship: location_of CCO:B0005662 ! XPO2_HUMAN relationship: location_of CCO:B0005663 ! TNPO1_HUMAN relationship: location_of CCO:B0005664 ! XPOT_HUMAN relationship: location_of CCO:B0005667 ! ELOC_HUMAN relationship: location_of CCO:B0005675 ! HIPK1_HUMAN relationship: location_of CCO:B0005680 ! AP2B_HUMAN relationship: location_of CCO:B0005682 ! CENPH_HUMAN relationship: location_of CCO:B0005688 ! WDR82_HUMAN relationship: location_of CCO:B0005691 ! SMU1_HUMAN relationship: location_of CCO:B0005693 ! ARI4A_HUMAN relationship: location_of CCO:B0005697 ! IMA5_HUMAN relationship: location_of CCO:B0005701 ! HDA11_HUMAN relationship: location_of CCO:B0005705 ! MYOD1_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0005713 ! ANM1_HUMAN relationship: location_of CCO:B0005715 ! ITF2_HUMAN relationship: location_of CCO:B0005729 ! DDX5_HUMAN relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0005768 ! RS3A_HUMAN relationship: location_of CCO:B0005776 ! RSSA_HUMAN relationship: location_of CCO:B0005779 ! ENOA_HUMAN relationship: location_of CCO:B0005780 ! MED27_HUMAN relationship: location_of CCO:B0005781 ! MED20_HUMAN relationship: location_of CCO:B0005782 ! MED7_HUMAN relationship: location_of CCO:B0005783 ! MED21_HUMAN relationship: location_of CCO:B0005784 ! MED31_HUMAN relationship: location_of CCO:B0005787 ! MED18_HUMAN relationship: location_of CCO:B0005789 ! MED12_HUMAN relationship: location_of CCO:B0005790 ! MED15_HUMAN relationship: location_of CCO:B0005791 ! MED16_HUMAN relationship: location_of CCO:B0005792 ! MED6_HUMAN relationship: location_of CCO:B0005793 ! MED23_HUMAN relationship: location_of CCO:B0005795 ! MED22_HUMAN relationship: location_of CCO:B0005796 ! 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STK19_HUMAN relationship: location_of CCO:B0005901 ! BCLX_HUMAN relationship: location_of CCO:B0005904 ! DPOE2_HUMAN relationship: location_of CCO:B0005917 ! MO4L1_HUMAN relationship: location_of CCO:B0005936 ! FANCF_HUMAN relationship: location_of CCO:B0005942 ! WASL_HUMAN relationship: location_of CCO:B0005943 ! APTX_HUMAN relationship: location_of CCO:B0005951 ! BRE_HUMAN relationship: location_of CCO:B0005974 ! NOTC1_HUMAN relationship: location_of CCO:B0005980 ! ZN363_HUMAN relationship: location_of CCO:B0005981 ! TRI27_HUMAN relationship: location_of CCO:B0005987 ! AES_HUMAN relationship: location_of CCO:B0005996 ! WDR57_HUMAN relationship: location_of CCO:B0006001 ! RFWD2_HUMAN relationship: location_of CCO:B0006002 ! TRIB1_HUMAN relationship: location_of CCO:B0006005 ! LSM1_HUMAN relationship: location_of CCO:B0006012 ! 4ET_HUMAN relationship: location_of CCO:B0006014 ! ZN443_HUMAN relationship: location_of CCO:B0006020 ! BC11A_HUMAN relationship: location_of CCO:B0006030 ! COE1_HUMAN relationship: location_of CCO:B0006031 ! PRGC1_HUMAN relationship: location_of CCO:B0006033 ! ARNT2_HUMAN relationship: location_of CCO:B0006036 ! ERCC5_HUMAN relationship: location_of CCO:B0006038 ! NKRF_HUMAN relationship: location_of CCO:B0006041 ! TBL1R_HUMAN relationship: location_of CCO:B0006048 ! HSF4_HUMAN relationship: location_of CCO:B0006049 ! PO2F3_HUMAN relationship: location_of CCO:B0006050 ! UTP6_HUMAN relationship: location_of CCO:B0006057 ! TFE2_HUMAN relationship: location_of CCO:B0006060 ! DAPK3_HUMAN relationship: location_of CCO:B0006064 ! CASC5_HUMAN relationship: location_of CCO:B0006070 ! EGR2_HUMAN relationship: location_of CCO:B0006076 ! CNBP1_HUMAN relationship: location_of CCO:B0006082 ! CHD3_HUMAN relationship: location_of CCO:B0006083 ! SBP1_HUMAN relationship: location_of CCO:B0006100 ! RPB3_HUMAN relationship: location_of CCO:B0006101 ! RPC6_HUMAN relationship: location_of CCO:B0006105 ! RFC5_HUMAN relationship: location_of CCO:B0006111 ! RSMN_HUMAN relationship: location_of CCO:B0006121 ! ATF3_HUMAN relationship: location_of CCO:B0006127 ! BAT3_HUMAN relationship: location_of CCO:B0006133 ! CSN6_HUMAN relationship: location_of CCO:B0006136 ! DJB11_HUMAN relationship: location_of CCO:B0006137 ! DNJB9_HUMAN relationship: location_of CCO:B0006138 ! TRDMT_HUMAN relationship: location_of CCO:B0006149 ! ID2_HUMAN relationship: location_of CCO:B0006169 ! WDR33_HUMAN relationship: location_of CCO:B0006186 ! DUS12_HUMAN relationship: location_of CCO:B0006189 ! ETHE1_HUMAN relationship: location_of CCO:B0006198 ! CENPR_HUMAN relationship: location_of CCO:B0006209 ! MYCBP_HUMAN relationship: location_of CCO:B0006218 ! PQBP1_HUMAN relationship: location_of CCO:B0006219 ! PSB10_HUMAN relationship: location_of CCO:B0006224 ! RECQ5_HUMAN relationship: location_of CCO:B0006227 ! PRKN2_HUMAN relationship: location_of CCO:B0006239 ! RED_HUMAN relationship: location_of CCO:B0006240 ! PNO1_HUMAN relationship: location_of CCO:B0006246 ! TGIF1_HUMAN relationship: location_of CCO:B0006254 ! ZNF7_HUMAN relationship: location_of CCO:B0006255 ! ABC3G_HUMAN relationship: location_of CCO:B0006256 ! ARL4D_HUMAN relationship: location_of CCO:B0006264 ! CSN7A_HUMAN relationship: location_of CCO:B0006271 ! BTBDA_HUMAN relationship: location_of CCO:B0006275 ! HNRPL_HUMAN relationship: location_of CCO:B0006294 ! PTOV1_HUMAN relationship: location_of CCO:B0006301 ! ST65G_HUMAN relationship: location_of CCO:B0006303 ! TCEA2_HUMAN relationship: location_of CCO:B0006305 ! UBP4_HUMAN relationship: location_of CCO:B0006309 ! TBL3_HUMAN relationship: location_of CCO:B0006311 ! BRD4_HUMAN relationship: location_of CCO:B0006328 ! FBX18_HUMAN relationship: location_of CCO:B0006333 ! TTLL5_HUMAN relationship: location_of CCO:B0006341 ! PO3F3_HUMAN relationship: location_of CCO:B0010371 ! 1433S_HUMAN-Phosphoserine216 relationship: location_of CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0010391 ! 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ATM_HUMAN-Phosphothreonine72 relationship: location_of CCO:B0010660 ! ATN1_HUMAN-Phosphoserine34 relationship: location_of CCO:B0010694 ! ATRIP_HUMAN-Phosphoserine518 relationship: location_of CCO:B0010699 ! ATRX_HUMAN-Phosphoserine92 relationship: location_of CCO:B0010721 ! ATX7_HUMAN-Phosphothreonine854 relationship: location_of CCO:B0010723 ! AURKB_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0010732 ! BAT2_HUMAN-Phosphoserine350 relationship: location_of CCO:B0010771 ! BCCIP_HUMAN-Phosphoserine112 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0010776 ! BCL9_HUMAN-Phosphoserine352 relationship: location_of CCO:B0010794 ! BIN1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0010825 ! BOREA_HUMAN-Phosphoserine219 relationship: location_of CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 relationship: location_of CCO:B0010865 ! BRD7_HUMAN-Phosphoserine279 relationship: location_of CCO:B0010867 ! BRSK1_HUMAN-Phosphoserine209 relationship: location_of CCO:B0010872 ! CABL1_HUMAN-Phosphoserine313 relationship: location_of CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: location_of CCO:B0010892 ! CAF1A_HUMAN-Phosphoserine123 relationship: location_of CCO:B0010903 ! CAF1B_HUMAN-Phosphothreonine495 relationship: location_of CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: location_of CCO:B0010939 ! CBLB_HUMAN-Phosphoserine480 relationship: location_of CCO:B0010952 ! CBL_HUMAN-Phosphoserine900 relationship: location_of CCO:B0010965 ! CBX1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0010993 ! CCNE1_HUMAN-Phosphothreonine77 relationship: location_of CCO:B0010997 ! CCNE2_HUMAN-Phosphothreonine392 relationship: location_of CCO:B0011000 ! CCNH_HUMAN-Phosphothreonine315 relationship: location_of CCO:B0011004 ! CCNL1_HUMAN-Phosphoserine65 relationship: location_of CCO:B0011007 ! CCNT2_HUMAN-Phosphoserine480 relationship: location_of CCO:B0011022 ! CD2L1_HUMAN-Phosphothreonine595 relationship: location_of CCO:B0011030 ! CD2L2_HUMAN-Phosphothreonine736 relationship: location_of CCO:B0011066 ! CDC26_HUMAN-Phosphoserine78 relationship: location_of CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: location_of CCO:B0011078 ! CDC2_HUMAN-Phosphothreonine14 relationship: location_of CCO:B0011087 ! CDC6_HUMAN-Phosphothreonine166 relationship: location_of CCO:B0011091 ! CDCA2_HUMAN-Phosphoserine401 relationship: location_of CCO:B0011105 ! CDK2_HUMAN-Phosphotyrosine19 relationship: location_of CCO:B0011112 ! CDK4_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0011119 ! CDK7_HUMAN-Phosphothreonine170 relationship: location_of CCO:B0011126 ! CDN1B_HUMAN-Phosphoserine10 relationship: location_of CCO:B0011129 ! CDT1_HUMAN-Phosphoserine318 relationship: location_of CCO:B0011131 ! CELF1_HUMAN-Phosphoserine302 relationship: location_of CCO:B0011143 ! CENPC_HUMAN-Phosphoserine520 relationship: location_of CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0011213 ! CHK1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0011292 ! CND1_HUMAN-Phosphoserine1376 relationship: location_of CCO:B0011307 ! CND3_HUMAN-Phosphoserine674 relationship: location_of CCO:B0011317 ! CNDG2_HUMAN-Phosphothreonine805 relationship: location_of CCO:B0011348 ! CREB1_HUMAN-Phosphoserine142 relationship: location_of CCO:B0011360 ! CSN1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0011362 ! CSN5_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0011392 ! CTND1_HUMAN-Phosphoserine269 relationship: location_of CCO:B0011413 ! CUL3_HUMAN-Phosphoserine737 relationship: location_of CCO:B0011424 ! DACH1_HUMAN-Phosphoserine581 relationship: location_of CCO:B0011456 ! DDB1_HUMAN-Phosphoserine766 relationship: location_of CCO:B0011457 ! DDB2_HUMAN-Phosphoserine24 relationship: location_of CCO:B0011473 ! DDX3X_HUMAN-Phosphoserine74 relationship: location_of CCO:B0011509 ! DHX9_HUMAN-Phosphotyrosine1241 relationship: location_of CCO:B0011519 ! DKC1_HUMAN-Phosphoserine513 relationship: location_of CCO:B0011545 ! DMAP1_HUMAN-Phosphoserine456 relationship: location_of CCO:B0011552 ! DNJB6_HUMAN-Phosphoserine277 relationship: location_of CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: location_of CCO:B0011577 ! DPOE1_HUMAN-Phosphoserine1940 relationship: location_of CCO:B0011579 ! DPOE4_HUMAN-Phosphoserine25 relationship: location_of CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 relationship: location_of CCO:B0011620 ! E2F1_HUMAN-Phosphoserine375 relationship: location_of CCO:B0011622 ! EAF1_HUMAN-Phosphoserine158 relationship: location_of CCO:B0011630 ! EDC4_HUMAN-Phosphoserine879 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0011669 ! EHMT1_HUMAN-Phosphoserine466 relationship: location_of CCO:B0011671 ! ELF1_HUMAN-Phosphoserine432 relationship: location_of CCO:B0011677 ! ELK1_HUMAN-Phosphoserine389 relationship: location_of CCO:B0011679 ! ELOB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011712 ! EP400_HUMAN-Phosphoserine736 relationship: location_of CCO:B0011717 ! EPAS1_HUMAN-Phosphothreonine840 relationship: location_of CCO:B0011719 ! EPC1_HUMAN-Phosphoserine357 relationship: location_of CCO:B0011752 ! ERCC5_HUMAN-Phosphoserine384 relationship: location_of CCO:B0011765 ! ESCO2_HUMAN-Phosphoserine29 relationship: location_of CCO:B0011767 ! ESPL1_HUMAN-Phosphoserine1508 relationship: location_of CCO:B0011798 ! EWS_HUMAN-Asymmetric dimethylarginine589 relationship: location_of CCO:B0011810 ! EXOS3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011811 ! EXOS4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011812 ! EXOS5_HUMAN-Phosphoserine20 relationship: location_of CCO:B0011819 ! FACD2_HUMAN-Phosphoserine717 relationship: location_of CCO:B0011845 ! FANCI_HUMAN-Phosphoserine556 relationship: location_of CCO:B0011857 ! FBRL_HUMAN-Asymmetric dimethylarginine36 relationship: location_of CCO:B0011874 ! FBXW7_HUMAN-Phosphoserine26 relationship: location_of CCO:B0011884 ! FL2D_HUMAN-Phosphoserine306 relationship: location_of CCO:B0011889 ! FOXN3_HUMAN-Phosphoserine85 relationship: location_of CCO:B0011896 ! FRK_HUMAN-Phosphotyrosine387 relationship: location_of CCO:B0011912 ! FZR_HUMAN-Phosphoserine151 relationship: location_of CCO:B0011929 ! GFI1B_HUMAN-Phosphoserine261 relationship: location_of CCO:B0011989 ! GRWD1_HUMAN-Phosphoserine122 relationship: location_of CCO:B0011999 ! H11_HUMAN-N-acetylserine2 relationship: location_of CCO:B0012002 ! H14_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0012013 ! H2B1C_HUMAN-N6-acetyllysine13 relationship: location_of CCO:B0012048 ! H31_HUMAN-N6-acetyllysine37 relationship: location_of CCO:B0012088 ! H32_HUMAN-N6-acetyllysine57 relationship: location_of CCO:B0012117 ! H33_HUMAN-N6-methyllysine28 relationship: location_of CCO:B0012158 ! HDAC1_HUMAN-Phosphoserine423 relationship: location_of CCO:B0012159 ! HDAC2_HUMAN-Phosphoserine394 relationship: location_of CCO:B0012164 ! HDAC4_HUMAN-Phosphoserine467 relationship: location_of CCO:B0012166 ! HDAC5_HUMAN-Phosphoserine259 relationship: location_of CCO:B0012168 ! HDAC6_HUMAN-Phosphoserine22 relationship: location_of CCO:B0012174 ! HDAC9_HUMAN-Phosphoserine451 relationship: location_of CCO:B0012175 ! HD_HUMAN-Phosphoserine421 relationship: location_of CCO:B0012180 ! HEXI1_HUMAN-Phosphoserine97 relationship: location_of CCO:B0012195 ! HIF1A_HUMAN-3-hydroxyasparagine803 relationship: location_of CCO:B0012198 ! HMGB1_HUMAN-Phosphoserine35 relationship: location_of CCO:B0012199 ! HNF1A_HUMAN-Phosphothreonine74 relationship: location_of CCO:B0012209 ! HNRH3_HUMAN-Asymmetric dimethylarginine121 relationship: location_of CCO:B0012223 ! HNRPD_HUMAN-Phosphoserine82 relationship: location_of CCO:B0012231 ! HNRPF_HUMAN-Phosphoserine161 relationship: location_of CCO:B0012250 ! HNRPK_HUMAN-Omega-N-methylated arginine296 relationship: location_of CCO:B0012274 ! HSP71_HUMAN-Phosphotyrosine611 relationship: location_of CCO:B0012280 ! HSPB1_HUMAN-Phosphoserine26 relationship: location_of CCO:B0012286 ! HTAI2_HUMAN-Phosphoserine45 relationship: location_of CCO:B0012288 ! HUWE1_HUMAN-Phosphoserine1907 relationship: location_of CCO:B0012347 ! IKKA_HUMAN-Phosphothreonine23 relationship: location_of CCO:B0012366 ! ILF3_HUMAN-Phosphoserine62 relationship: location_of CCO:B0012377 ! IMA2_HUMAN-Phosphoserine490 relationship: location_of CCO:B0012378 ! IMA3_HUMAN-Phosphoserine60 relationship: location_of CCO:B0012399 ! INCE_HUMAN-Phosphoserine296 relationship: location_of CCO:B0012417 ! ING4_HUMAN-N6-acetyllysine148 relationship: location_of CCO:B0012448 ! JUNB_HUMAN-Phosphoserine259 relationship: location_of CCO:B0012449 ! JUN_HUMAN-Phosphoserine63 relationship: location_of CCO:B0012512 ! KC1E_HUMAN-Phosphoserine363 relationship: location_of CCO:B0012522 ! KHDR1_HUMAN-Omega-N-methylarginine315 relationship: location_of CCO:B0012528 ! KHDR3_HUMAN-Phosphotyrosine5 relationship: location_of CCO:B0012594 ! KIF23_HUMAN-Phosphoserine682 relationship: location_of CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0012613 ! KNTC1_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0012627 ! KPCA_HUMAN-Phosphoserine657 relationship: location_of CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0012643 ! KS6A4_HUMAN-Phosphoserine682 relationship: location_of CCO:B0012651 ! KU70_HUMAN-Phosphoserine51 relationship: location_of CCO:B0012656 ! KU86_HUMAN-Phosphothreonine715 relationship: location_of CCO:B0012698 ! LIMK1_HUMAN-Phosphoserine298 relationship: location_of CCO:B0012706 ! LSD1_HUMAN-Phosphoserine166 relationship: location_of CCO:B0012707 ! LSM3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012762 ! MAPK5_HUMAN-Phosphothreonine182 relationship: location_of CCO:B0012794 ! MAX_HUMAN-Phosphoserine2 relationship: location_of CCO:B0012801 ! MBD1_HUMAN-Phosphoserine295 relationship: location_of CCO:B0012803 ! MCM10_HUMAN-Phosphothreonine85 relationship: location_of CCO:B0012807 ! MCM2_HUMAN-Phosphoserine27 relationship: location_of CCO:B0012814 ! MCM3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012838 ! MCM6_HUMAN-Phosphothreonine791 relationship: location_of CCO:B0012841 ! MCRS1_HUMAN-Phosphoserine108 relationship: location_of CCO:B0012844 ! MD1L1_HUMAN-Phosphoserine214 relationship: location_of CCO:B0012846 ! MD2BP_HUMAN-Phosphoserine29 relationship: location_of CCO:B0012863 ! MDC1_HUMAN-Phosphothreonine523 relationship: location_of CCO:B0012890 ! MED17_HUMAN-Phosphoserine37 relationship: location_of CCO:B0012901 ! MED1_HUMAN-Phosphothreonine1032 relationship: location_of CCO:B0012906 ! MED24_HUMAN-Phosphoserine862 relationship: location_of CCO:B0012966 ! MLTK_HUMAN-Phosphoserine635 relationship: location_of CCO:B0012994 ! MPP8_HUMAN-Phosphoserine164 relationship: location_of CCO:B0013014 ! MSH2_HUMAN-Phosphoserine860 relationship: location_of CCO:B0013022 ! MSH6_HUMAN-Phosphoserine227 relationship: location_of CCO:B0013046 ! MTUS1_HUMAN-Phosphoserine1264 relationship: location_of CCO:B0013054 ! MYBB_HUMAN-Phosphothreonine494 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013079 ! MYST2_HUMAN-Phosphothreonine88 relationship: location_of CCO:B0013088 ! NACA_HUMAN-Phosphothreonine161 relationship: location_of CCO:B0013102 ! NASP_HUMAN-Phosphoserine726 relationship: location_of CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0013145 ! NEK1_HUMAN-Phosphothreonine162 relationship: location_of CCO:B0013156 ! NEK9_HUMAN-Phosphoserine869 relationship: location_of CCO:B0013158 ! NEP1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013164 ! NFKB2_HUMAN-Phosphoserine713 relationship: location_of CCO:B0013178 ! NIPA_HUMAN-Phosphoserine354 relationship: location_of CCO:B0013192 ! NIPBL_HUMAN-Phosphoserine1096 relationship: location_of CCO:B0013200 ! NOG1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013206 ! NOL12_HUMAN-Phosphoserine140 relationship: location_of CCO:B0013217 ! NOL1_HUMAN-Phosphothreonine195 relationship: location_of CCO:B0013224 ! NOLC1_HUMAN-Phosphoserine87 relationship: location_of CCO:B0013244 ! NP1L1_HUMAN-Phosphoserine10 relationship: location_of CCO:B0013263 ! NSL1_HUMAN-Phosphothreonine242 relationship: location_of CCO:B0013270 ! NUCL_HUMAN-Phosphoserine34 relationship: location_of CCO:B0013288 ! NUDC_HUMAN-Phosphoserine274 relationship: location_of CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0013334 ! ORC3_HUMAN-Phosphoserine208 relationship: location_of CCO:B0013336 ! ORC6_HUMAN-Phosphothreonine195 relationship: location_of CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013353 ! P66A_HUMAN-Phosphoserine114 relationship: location_of CCO:B0013361 ! P73_HUMAN-Phosphotyrosine99 relationship: location_of CCO:B0013366 ! PA2G4_HUMAN-Phosphoserine2 relationship: location_of CCO:B0013372 ! PABP1_HUMAN-Omega-N-methylated arginine493 relationship: location_of CCO:B0013399 ! PARN_HUMAN-Phosphoserine557 relationship: location_of CCO:B0013450 ! PDCD4_HUMAN-Phosphoserine76 relationship: location_of CCO:B0013485 ! PDS5A_HUMAN-Phosphothreonine1208 relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0013503 ! PHC2_HUMAN-Phosphoserine704 relationship: location_of CCO:B0013509 ! PIAS1_HUMAN-Phosphoserine483 relationship: location_of CCO:B0013514 ! PIN1_HUMAN-Phosphoserine108 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0013563 ! PLCB1_HUMAN-N6-acetyllysine976 relationship: location_of CCO:B0013571 ! PLK1_HUMAN-Phosphoserine335 relationship: location_of CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: location_of CCO:B0013587 ! PMS2_HUMAN-Phosphothreonine573 relationship: location_of CCO:B0013593 ! PO2F1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0013601 ! PPIA_HUMAN-Phosphoserine21 relationship: location_of CCO:B0013606 ! PPM1G_HUMAN-Phosphoserine527 relationship: location_of CCO:B0013610 ! PRC1_HUMAN-Phosphothreonine481 relationship: location_of CCO:B0013613 ! PROF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013617 ! PRS4_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0013620 ! PSA3_HUMAN-Phosphotyrosine161 relationship: location_of CCO:B0013652 ! PYGO2_HUMAN-Phosphothreonine302 relationship: location_of CCO:B0013654 ! QN1_HUMAN-Phosphoserine776 relationship: location_of CCO:B0013662 ! RAD17_HUMAN-Phosphothreonine304 relationship: location_of CCO:B0013674 ! RAD9A_HUMAN-Phosphoserine328 relationship: location_of CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013711 ! RARA_HUMAN-Phosphoserine449 relationship: location_of CCO:B0013722 ! RBBP5_HUMAN-Phosphothreonine252 relationship: location_of CCO:B0013749 ! RBBP8_HUMAN-Phosphoserine679 relationship: location_of CCO:B0013761 ! RBL1_HUMAN-Phosphoserine975 relationship: location_of CCO:B0013770 ! RBL2_HUMAN-Phosphoserine948 relationship: location_of CCO:B0013792 ! RBM5_HUMAN-Phosphoserine624 relationship: location_of CCO:B0013797 ! RBM8A_HUMAN-Phosphoserine166 relationship: location_of CCO:B0013804 ! RB_HUMAN-Phosphothreonine826 relationship: location_of CCO:B0013809 ! RCC1_HUMAN-Phosphothreonine411 relationship: location_of CCO:B0013810 ! RCC2_HUMAN-Phosphothreonine20 relationship: location_of CCO:B0013823 ! RFA2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013831 ! RFC1_HUMAN-Phosphothreonine110 relationship: location_of CCO:B0013836 ! RFX1_HUMAN-Phosphoserine120 relationship: location_of CCO:B0013855 ! RGC32_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0013908 ! RNC_HUMAN-Phosphoserine284 relationship: location_of CCO:B0013910 ! ROA1_HUMAN-Phosphoserine4 relationship: location_of CCO:B0013926 ! ROA2_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013930 ! RPAC1_HUMAN-Phosphotyrosine33 relationship: location_of CCO:B0013948 ! S100B_HUMAN-Blocked amino end (Ser)2 relationship: location_of CCO:B0013956 ! SAE1_HUMAN-Phosphoserine185 relationship: location_of CCO:B0013960 ! SAS10_HUMAN-Phosphoserine368 relationship: location_of CCO:B0013988 ! SENP7_HUMAN-Phosphoserine377 relationship: location_of CCO:B0013991 ! SEPT2_HUMAN-Phosphotyrosine17 relationship: location_of CCO:B0014006 ! SEPT7_HUMAN-Phosphoserine423 relationship: location_of CCO:B0014023 ! SETB1_HUMAN-Phosphoserine1190 relationship: location_of CCO:B0014029 ! SFPQ_HUMAN-Omega-N-methylated arginine25 relationship: location_of CCO:B0014041 ! SFRS1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0014044 ! SGOL2_HUMAN-Phosphothreonine845 relationship: location_of CCO:B0014052 ! SH3B4_HUMAN-Phosphoserine637 relationship: location_of CCO:B0014066 ! SKIV2_HUMAN-Phosphoserine366 relationship: location_of CCO:B0014070 ! SMC1A_HUMAN-Phosphoserine951 relationship: location_of CCO:B0014074 ! SMC1B_HUMAN-Phosphoserine882 relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: location_of CCO:B0014085 ! SMC4_HUMAN-Phosphoserine1056 relationship: location_of CCO:B0014128 ! SN1L1_HUMAN-Phosphothreonine182 relationship: location_of CCO:B0014135 ! SN1L2_HUMAN-Phosphoserine587 relationship: location_of CCO:B0014137 ! SNIP1_HUMAN-Phosphoserine35 relationship: location_of CCO:B0014148 ! SNUT1_HUMAN-Phosphoserine596 relationship: location_of CCO:B0014187 ! SPT5H_HUMAN-Phosphothreonine775 relationship: location_of CCO:B0014221 ! SSRP1_HUMAN-Phosphoserine444 relationship: location_of CCO:B0014238 ! STA5B_HUMAN-Phosphotyrosine699 relationship: location_of CCO:B0014239 ! STAG1_HUMAN-Phosphoserine1069 relationship: location_of CCO:B0014253 ! STK11_HUMAN-Phosphoserine428 relationship: location_of CCO:B0014254 ! STK4_HUMAN-Phosphothreonine183 relationship: location_of CCO:B0014267 ! STRAD_HUMAN-Phosphothreonine419 relationship: location_of CCO:B0014272 ! SUMO1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0014280 ! T2FA_HUMAN-Phosphoserine307 relationship: location_of CCO:B0014295 ! TACC1_HUMAN-Phosphoserine52 relationship: location_of CCO:B0014304 ! TACC2_HUMAN-Phosphoserine2512 relationship: location_of CCO:B0014328 ! TE2IP_HUMAN-Phosphoserine154 relationship: location_of CCO:B0014336 ! TERF2_HUMAN-Phosphoserine380 relationship: location_of CCO:B0014378 ! TIP60_HUMAN-Phosphoserine86 relationship: location_of CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: location_of CCO:B0014391 ! TLE1_HUMAN-Phosphoserine263 relationship: location_of CCO:B0014395 ! TLE2_HUMAN-Phosphoserine249 relationship: location_of CCO:B0014413 ! TLK2_HUMAN-Phosphoserine99 relationship: location_of CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: location_of CCO:B0014528 ! TPX2_HUMAN-Phosphoserine654 relationship: location_of CCO:B0014537 ! TRP13_HUMAN-Phosphotyrosine56 relationship: location_of CCO:B0014549 ! TSYL2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0014560 ! TYY1_HUMAN-Phosphoserine184 relationship: location_of CCO:B0014563 ! UB2R1_HUMAN-Phosphoserine231 relationship: location_of CCO:B0014564 ! UBE3A_HUMAN-Phosphoserine218 relationship: location_of CCO:B0014578 ! UHRF1_HUMAN-Phosphoserine298 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0014589 ! UT14A_HUMAN-Phosphoserine445 relationship: location_of CCO:B0014651 ! WAPL_HUMAN-Phosphoserine226 relationship: location_of CCO:B0014658 ! WBP11_HUMAN-Phosphoserine253 relationship: location_of CCO:B0014675 ! WDR5_HUMAN-Phosphoserine267 relationship: location_of CCO:B0014694 ! WEE1_HUMAN-Phosphoserine642 relationship: location_of CCO:B0014698 ! WRN_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0014709 ! XPC_HUMAN-Phosphoserine347 relationship: location_of CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 relationship: location_of CCO:B0014717 ! XRCC2_HUMAN-Phosphoserine247 relationship: location_of CCO:B0014725 ! YBOX1_HUMAN-Phosphoserine165 relationship: location_of CCO:B0014743 ! ZHX1_HUMAN-Phosphoserine48 relationship: location_of CCO:B0014746 ! ZNF24_HUMAN-Phosphoserine261 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0014928 ! TAF9B_HUMAN relationship: location_of CCO:B0014938 ! AIFM1_HUMAN relationship: location_of CCO:B0015066 ! FOXN2_HUMAN relationship: location_of CCO:B0015067 ! Q6P4Q2_HUMAN relationship: location_of CCO:B0015073 ! RBMS1_HUMAN relationship: location_of CCO:B0015243 ! TCEA3_HUMAN relationship: location_of CCO:B0015270 ! DFFB_HUMAN relationship: location_of CCO:B0015397 ! Q9H7H9_HUMAN relationship: location_of CCO:B0015398 ! MXI1_HUMAN relationship: location_of CCO:B0015399 ! MAD4_HUMAN relationship: location_of CCO:B0015400 ! MAD1_HUMAN relationship: location_of CCO:B0015493 ! SUV42_HUMAN relationship: location_of CCO:B0015494 ! SUV41_HUMAN relationship: location_of CCO:B0015646 ! ERCC1_HUMAN relationship: location_of CCO:B0015701 ! Q8N6B5_HUMAN relationship: location_of CCO:B0015705 ! Q8NAN6_HUMAN relationship: location_of CCO:B0015706 ! Q0PRL4_HUMAN relationship: location_of CCO:B0015709 ! Q8N2P0_HUMAN relationship: location_of CCO:B0015710 ! Q7Z7F8_HUMAN relationship: location_of CCO:B0015712 ! FOXP1_HUMAN relationship: location_of CCO:B0015715 ! Q96AP5_HUMAN relationship: location_of CCO:B0015717 ! FOXP2_HUMAN relationship: location_of CCO:B0015718 ! Q68DX8_HUMAN relationship: location_of CCO:B0015719 ! Q8IW55_HUMAN relationship: location_of CCO:B0015721 ! A3KMG1_HUMAN relationship: location_of CCO:B0015979 ! MNDA_HUMAN relationship: location_of CCO:B0016195 ! KHDR2_HUMAN relationship: location_of CCO:B0016220 ! DNJB1_HUMAN relationship: location_of CCO:B0016306 ! PP2BA_HUMAN relationship: location_of CCO:B0016329 ! AAKG1_HUMAN relationship: location_of CCO:B0016694 ! FOXI1_HUMAN relationship: location_of CCO:B0016695 ! FOXE1_HUMAN relationship: location_of CCO:B0016696 ! FOXD2_HUMAN relationship: location_of CCO:B0016698 ! FX4L4_HUMAN relationship: location_of CCO:B0016699 ! FOXF1_HUMAN relationship: location_of CCO:B0016702 ! Q4JHB7_HUMAN relationship: location_of CCO:B0016703 ! Q6VB86_HUMAN relationship: location_of CCO:B0016706 ! FOXD1_HUMAN relationship: location_of CCO:B0016708 ! FX4L1_HUMAN relationship: location_of CCO:B0016714 ! FOXB2_HUMAN relationship: location_of CCO:B0016715 ! FOXQ1_HUMAN relationship: location_of CCO:B0016719 ! FOXF2_HUMAN relationship: location_of CCO:B0016720 ! FX4L5_HUMAN relationship: location_of CCO:B0016722 ! FOXL1_HUMAN relationship: location_of CCO:B0016723 ! Q8WXT4_HUMAN relationship: location_of CCO:B0016724 ! FX4L6_HUMAN relationship: location_of CCO:B0016726 ! Q14CL2_HUMAN relationship: location_of CCO:B0016727 ! FOXE3_HUMAN relationship: location_of CCO:B0016733 ! FOXD3_HUMAN relationship: location_of CCO:B0016737 ! FX4L3_HUMAN relationship: location_of CCO:B0016740 ! FOXG1_HUMAN relationship: location_of CCO:B0016741 ! Q5T109_HUMAN relationship: location_of CCO:B0016782 ! ACL6B_HUMAN relationship: location_of CCO:B0016794 ! PLAG1_HUMAN relationship: location_of CCO:B0016798 ! PLAL2_HUMAN relationship: location_of CCO:B0016909 ! A6NFH2_HUMAN relationship: location_of CCO:B0016914 ! Q9Y6S1_HUMAN relationship: location_of CCO:B0016921 ! A6NFJ3_HUMAN relationship: location_of CCO:B0016926 ! A6NIY7_HUMAN relationship: location_of CCO:B0017050 ! Q6LES9_HUMAN relationship: location_of CCO:B0017097 ! Z816A_HUMAN relationship: location_of CCO:B0017101 ! ZN528_HUMAN relationship: location_of CCO:B0017103 ! ZNF83_HUMAN relationship: location_of CCO:B0017118 ! ING2_HUMAN relationship: location_of CCO:B0017601 ! ZNFX1_HUMAN relationship: location_of CCO:B0017668 ! FGF12_HUMAN relationship: location_of CCO:B0017676 ! FGF13_HUMAN relationship: location_of CCO:B0017677 ! FGF14_HUMAN relationship: location_of CCO:B0017820 ! NOTC3_HUMAN relationship: location_of CCO:B0017875 ! ZFP62_HUMAN relationship: location_of CCO:B0017876 ! Q6ZN27_HUMAN relationship: location_of CCO:B0017883 ! ZN616_HUMAN relationship: location_of CCO:B0017884 ! ZN546_HUMAN relationship: location_of CCO:B0017892 ! A4D2A2_HUMAN relationship: location_of CCO:B0017902 ! RBM38_HUMAN relationship: location_of CCO:B0017927 ! MYST3_HUMAN relationship: location_of CCO:B0017931 ! MYST4_HUMAN relationship: location_of CCO:B0017945 ! PURB_HUMAN relationship: location_of CCO:B0017947 ! PHF5A_HUMAN relationship: location_of CCO:B0017957 ! RFC4_HUMAN relationship: location_of CCO:B0018024 ! ZPR1_HUMAN relationship: location_of CCO:B0018046 ! NXF1_HUMAN relationship: location_of CCO:B0018160 ! CC14B_HUMAN relationship: location_of CCO:B0018189 ! PYDC1_HUMAN relationship: location_of CCO:B0018285 ! TF2H2_HUMAN relationship: location_of CCO:B0018381 ! A1L3Z2_HUMAN relationship: location_of CCO:B0018382 ! CREB5_HUMAN relationship: location_of CCO:B0018461 ! PIAS3_HUMAN relationship: location_of CCO:B0018465 ! ZN326_HUMAN relationship: location_of CCO:B0018552 ! Q4VXV6_HUMAN relationship: location_of CCO:B0018555 ! Q4VXV5_HUMAN relationship: location_of CCO:B0018662 ! Q8IW86_HUMAN relationship: location_of CCO:B0018664 ! TBX22_HUMAN relationship: location_of CCO:B0018665 ! Q9HA44_HUMAN relationship: location_of CCO:B0018667 ! Q5JT54_HUMAN relationship: location_of CCO:B0018668 ! TBX1_HUMAN relationship: location_of CCO:B0018669 ! TBX15_HUMAN relationship: location_of CCO:B0018670 ! TBX6_HUMAN relationship: location_of CCO:B0018671 ! Q5JZ06_HUMAN relationship: location_of CCO:B0018672 ! Q000T4_HUMAN relationship: location_of CCO:B0018676 ! TBX10_HUMAN relationship: location_of CCO:B0018677 ! TBX18_HUMAN relationship: location_of CCO:B0018678 ! TBX20_HUMAN relationship: location_of CCO:B0018951 ! ATF6A_HUMAN relationship: location_of CCO:B0018982 ! SNF8_HUMAN relationship: location_of CCO:B0019065 ! Q495X4_HUMAN relationship: location_of CCO:B0019067 ! RORA_HUMAN relationship: location_of CCO:B0019068 ! RORB_HUMAN relationship: location_of CCO:B0019239 ! Q5FBX3_HUMAN relationship: location_of CCO:B0019363 ! TAF5L_HUMAN relationship: location_of CCO:B0019365 ! TAF5_HUMAN relationship: location_of CCO:B0019407 ! Q6W9G7_HUMAN relationship: location_of CCO:B0019411 ! Q6P1W9_HUMAN relationship: location_of CCO:B0019498 ! SCND1_HUMAN relationship: location_of CCO:B0019606 ! BUD31_HUMAN relationship: location_of CCO:B0019813 ! A6NMQ1_HUMAN relationship: location_of CCO:B0019963 ! TISD_HUMAN relationship: location_of CCO:B0020040 ! A3RLL6_HUMAN relationship: location_of CCO:B0020218 ! CSEN_HUMAN relationship: location_of CCO:B0020253 ! SOX12_HUMAN relationship: location_of CCO:B0020256 ! SOX1_HUMAN relationship: location_of CCO:B0020258 ! O95131_HUMAN relationship: location_of CCO:B0020259 ! SOX18_HUMAN relationship: location_of CCO:B0020263 ! SOX21_HUMAN relationship: location_of CCO:B0020266 ! SOX30_HUMAN relationship: location_of CCO:B0020267 ! SOX14_HUMAN relationship: location_of CCO:B0020275 ! SOX3_HUMAN relationship: location_of CCO:B0020282 ! SRY_HUMAN relationship: location_of CCO:B0020283 ! SOX15_HUMAN relationship: location_of CCO:B0020286 ! O95130_HUMAN relationship: location_of CCO:B0020291 ! O95132_HUMAN relationship: location_of CCO:B0020292 ! SOX4_HUMAN relationship: location_of CCO:B0020295 ! SOX2_HUMAN relationship: location_of CCO:B0020296 ! Q52MY2_HUMAN relationship: location_of CCO:B0020529 ! IMA7_HUMAN relationship: location_of CCO:B0020552 ! RING2_HUMAN relationship: location_of CCO:B0020553 ! RING1_HUMAN relationship: location_of CCO:B0020771 ! RGS3_HUMAN relationship: location_of CCO:B0020777 ! RGS13_HUMAN relationship: location_of CCO:B0020932 ! GLIS1_HUMAN relationship: location_of CCO:B0020951 ! MP2K7_HUMAN relationship: location_of CCO:B0021032 ! CHD2_HUMAN relationship: location_of CCO:B0021154 ! Q6PIQ2_HUMAN relationship: location_of CCO:B0021155 ! Q86VG0_HUMAN relationship: location_of CCO:B0021156 ! SCND2_HUMAN relationship: location_of CCO:B0021159 ! Q86V93_HUMAN relationship: location_of CCO:B0021160 ! Q07644_HUMAN relationship: location_of CCO:B0021241 ! TF2LX_HUMAN relationship: location_of CCO:B0021248 ! Q3ZCM9_HUMAN relationship: location_of CCO:B0021260 ! TF2LY_HUMAN relationship: location_of CCO:B0021266 ! TGIF2_HUMAN relationship: location_of CCO:B0021341 ! CSDC2_HUMAN relationship: location_of CCO:B0021435 ! ATF4_HUMAN relationship: location_of CCO:B0021669 ! DUS2_HUMAN relationship: location_of CCO:B0021706 ! CITE1_HUMAN relationship: location_of CCO:B0021707 ! CITE4_HUMAN relationship: location_of CCO:B0021709 ! RPAC2_HUMAN relationship: location_of CCO:B0021718 ! NUP62_HUMAN relationship: location_of CCO:B0021755 ! A0N2G3_HUMAN relationship: location_of CCO:B0021778 ! RNH2A_HUMAN relationship: location_of CCO:B0021866 ! IKZF4_HUMAN relationship: location_of CCO:B0021914 ! H2A2A_HUMAN relationship: location_of CCO:B0022038 ! ZHX2_HUMAN relationship: location_of CCO:B0022042 ! Q6NUJ7_HUMAN relationship: location_of CCO:B0022045 ! Q5JZ70_HUMAN relationship: location_of CCO:B0022046 ! Q5JZ69_HUMAN relationship: location_of CCO:B0022073 ! SMC6_HUMAN relationship: location_of CCO:B0022200 ! CSN4_HUMAN relationship: location_of CCO:B0022204 ! PSA5_HUMAN relationship: location_of CCO:B0022223 ! ID1_HUMAN relationship: location_of CCO:B0022226 ! ID4_HUMAN relationship: location_of CCO:B0022296 ! Q3LRW1_HUMAN relationship: location_of CCO:B0022298 ! Q3LRW4_HUMAN relationship: location_of CCO:B0022300 ! P63_HUMAN relationship: location_of CCO:B0022308 ! Q1MSW9_HUMAN relationship: location_of CCO:B0022312 ! Q3LRW3_HUMAN relationship: location_of CCO:B0022381 ! ZN667_HUMAN relationship: location_of CCO:B0022382 ! Q9ULA1_HUMAN relationship: location_of CCO:B0022452 ! PER3_HUMAN relationship: location_of CCO:B0022617 ! A6ZIS4_HUMAN relationship: location_of CCO:B0022629 ! A6ZIT3_HUMAN relationship: location_of CCO:B0022781 ! PIM1_HUMAN relationship: location_of CCO:B0022832 ! BCL6B_HUMAN relationship: location_of CCO:B0023192 ! SMD1_HUMAN relationship: location_of CCO:B0023365 ! PPRC1_HUMAN relationship: location_of CCO:B0023371 ! HIC2_HUMAN relationship: location_of CCO:B0023422 ! STAT2_HUMAN relationship: location_of CCO:B0023430 ! Q67C41_HUMAN relationship: location_of CCO:B0023496 ! A4D2B3_HUMAN relationship: location_of CCO:B0023501 ! TAF6L_HUMAN relationship: location_of CCO:B0023930 ! BRM1L_HUMAN relationship: location_of CCO:B0023973 ! TF2H3_HUMAN relationship: location_of CCO:B0024005 ! UBP22_HUMAN relationship: location_of CCO:B0024266 ! POGZ_HUMAN relationship: location_of CCO:B0024299 ! IPO11_HUMAN relationship: location_of CCO:B0024344 ! Q9UG28_HUMAN relationship: location_of CCO:B0024423 ! Q59EG3_HUMAN relationship: location_of CCO:B0024426 ! Q53GX1_HUMAN relationship: location_of CCO:B0024428 ! Q0ZAJ5_HUMAN relationship: location_of CCO:B0024477 ! BNC2_HUMAN relationship: location_of CCO:B0024549 ! Q4LE28_HUMAN relationship: location_of CCO:B0024552 ! O60424_HUMAN relationship: location_of CCO:B0024762 ! POLK_HUMAN relationship: location_of CCO:B0024778 ! TNPO2_HUMAN relationship: location_of CCO:B0024794 ! ZIC3_HUMAN relationship: location_of CCO:B0024799 ! ZIC1_HUMAN relationship: location_of CCO:B0024842 ! RARB_HUMAN relationship: location_of CCO:B0024846 ! Q3SB16_HUMAN relationship: location_of CCO:B0024847 ! Q15156_HUMAN relationship: location_of CCO:B0024850 ! Q658K5_HUMAN relationship: location_of CCO:B0024873 ! NR6A1_HUMAN relationship: location_of CCO:B0024874 ! COT1_HUMAN relationship: location_of CCO:B0024875 ! COT2_HUMAN relationship: location_of CCO:B0024877 ! Q7Z5U9_HUMAN relationship: location_of CCO:B0024878 ! RXRB_HUMAN relationship: location_of CCO:B0024881 ! RXRG_HUMAN relationship: location_of CCO:B0024884 ! Q5STQ1_HUMAN relationship: location_of CCO:B0024886 ! RXRA_HUMAN relationship: location_of CCO:B0024889 ! Q3KQR7_HUMAN relationship: location_of CCO:B0024893 ! NR2F6_HUMAN relationship: location_of CCO:B0024942 ! Q6NVK3_HUMAN relationship: location_of CCO:B0024966 ! Q308M6_HUMAN relationship: location_of CCO:B0025035 ! Q7Z324_HUMAN relationship: location_of CCO:B0025086 ! Q6Q9Z7_HUMAN relationship: location_of CCO:B0025212 ! SBDS_HUMAN relationship: location_of CCO:B0025365 ! OVOL2_HUMAN relationship: location_of CCO:B0025407 ! NFIX_HUMAN relationship: location_of CCO:B0025409 ! Q7Z3K7_HUMAN relationship: location_of CCO:B0025410 ! Q5W0Y9_HUMAN relationship: location_of CCO:B0025417 ! Q8TA97_HUMAN relationship: location_of CCO:B0025419 ! Q6ZNF9_HUMAN relationship: location_of CCO:B0025421 ! Q5VW27_HUMAN relationship: location_of CCO:B0025422 ! Q13051_HUMAN relationship: location_of CCO:B0025423 ! Q5VW31_HUMAN relationship: location_of CCO:B0025428 ! Q5VW30_HUMAN relationship: location_of CCO:B0025429 ! Q5VW29_HUMAN relationship: location_of CCO:B0025430 ! Q5VW26_HUMAN relationship: location_of CCO:B0025434 ! Q59F49_HUMAN relationship: location_of CCO:B0025485 ! Q2A130_HUMAN relationship: location_of CCO:B0026033 ! SPCS_HUMAN relationship: location_of CCO:B0026181 ! SF3B3_HUMAN relationship: location_of CCO:B0026248 ! ERCC2_HUMAN relationship: location_of CCO:B0026249 ! ZMY11_HUMAN relationship: location_of CCO:B0026252 ! NOXIN_HUMAN relationship: location_of CCO:B0026268 ! CACO2_HUMAN relationship: location_of CCO:B0026347 ! ANDR_HUMAN-Phosphotyrosine915 relationship: location_of CCO:B0026377 ! EIF3K_HUMAN-Phosphoserine217 relationship: location_of CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: location_of CCO:B0026382 ! NF1_HUMAN-Phosphoserine2829 relationship: location_of CCO:B0026392 ! TCF19_HUMAN-Phosphoserine78 relationship: location_of CCO:B0026435 ! UK114_HUMAN relationship: location_of CCO:B0026467 ! HSF1_HUMAN relationship: location_of CCO:B0026475 ! Q6ZTI4_HUMAN relationship: location_of CCO:B0026476 ! A8MW26_HUMAN relationship: location_of CCO:B0026489 ! HSF2_HUMAN relationship: location_of CCO:B0026530 ! NPAS2_HUMAN relationship: location_of CCO:B0026531 ! CLOCK_HUMAN relationship: location_of CCO:B0026532 ! Q53EU0_HUMAN relationship: location_of CCO:B0026533 ! PASD1_HUMAN relationship: location_of CCO:B0026534 ! A6NP27_HUMAN relationship: location_of CCO:B0026862 ! A8K7L7_HUMAN relationship: location_of CCO:B0026863 ! A8MUP8_HUMAN relationship: location_of CCO:B0026978 ! DPH3_HUMAN relationship: location_of CCO:B0027079 ! GT2D1_HUMAN relationship: location_of CCO:B0027165 ! CDKL2_HUMAN relationship: location_of CCO:B0027184 ! Q6ZQQ5_HUMAN relationship: location_of CCO:B0027581 ! TBCD1_HUMAN relationship: location_of CCO:B0027730 ! SIN1_HUMAN relationship: location_of CCO:B0028072 ! Q5JTM4_HUMAN relationship: location_of CCO:B0028073 ! RFX3_HUMAN relationship: location_of CCO:B0028074 ! RFX2_HUMAN relationship: location_of CCO:B0028081 ! A8K581_HUMAN relationship: location_of CCO:B0028088 ! Q5JTM3_HUMAN relationship: location_of CCO:B0028295 ! A8MSJ8_HUMAN relationship: location_of CCO:B0028341 ! Q59GI1_HUMAN relationship: location_of CCO:B0028502 ! ERCC3_HUMAN relationship: location_of CCO:B0028510 ! MYBA_HUMAN relationship: location_of CCO:B0028526 ! A8MXH7_HUMAN relationship: location_of CCO:B0028528 ! Q495F9_HUMAN relationship: location_of CCO:B0028530 ! Q5THS6_HUMAN relationship: location_of CCO:B0028532 ! Q708E2_HUMAN relationship: location_of CCO:B0028677 ! PADI4_HUMAN relationship: location_of CCO:B0028704 ! A8MX32_HUMAN relationship: location_of CCO:B0029172 ! TSAP1_HUMAN relationship: location_of CCO:B0029283 ! ZSC20_HUMAN relationship: location_of CCO:B0029287 ! A6NJN6_HUMAN relationship: location_of CCO:B0029357 ! EGLN2_HUMAN relationship: location_of CCO:B0029358 ! EGLN3_HUMAN relationship: location_of CCO:B0029451 ! Z3H7B_HUMAN relationship: location_of CCO:B0029480 ! Q8NHM1_HUMAN relationship: location_of CCO:B0029482 ! LHX3_HUMAN relationship: location_of CCO:B0029488 ! Q9HBU2_HUMAN relationship: location_of CCO:B0029683 ! Q56TK0_HUMAN relationship: location_of CCO:B0030140 ! Q5C8S5_HUMAN relationship: location_of CCO:B0030141 ! Q0H8T6_HUMAN relationship: location_of CCO:B0030142 ! Q9UE35_HUMAN relationship: location_of CCO:B0030143 ! Q6MZQ9_HUMAN relationship: location_of CCO:B0030185 ! A8MS99_HUMAN relationship: location_of CCO:B0030312 ! ETV3_HUMAN relationship: location_of CCO:B0030313 ! ETS1_HUMAN relationship: location_of CCO:B0030315 ! ETV2_HUMAN relationship: location_of CCO:B0030316 ! ETS2_HUMAN relationship: location_of CCO:B0030317 ! Q6N087_HUMAN relationship: location_of CCO:B0030323 ! Q3KNT2_HUMAN relationship: location_of CCO:B0030326 ! A6NFN5_HUMAN relationship: location_of CCO:B0030504 ! Q5VVI0_HUMAN relationship: location_of CCO:B0030506 ! NGN2_HUMAN relationship: location_of CCO:B0030509 ! NGN3_HUMAN relationship: location_of CCO:B0030752 ! CSN3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0030758 ! RIR2B_HUMAN relationship: location_of CCO:B0030804 ! PSB8_HUMAN relationship: location_of CCO:B0030806 ! PSB5_HUMAN relationship: location_of CCO:B0030929 ! PSB3_HUMAN relationship: location_of CCO:B0030954 ! RPB4_HUMAN relationship: location_of CCO:B0031007 ! PSB9_HUMAN relationship: location_of CCO:B0031015 ! PSB6_HUMAN relationship: location_of CCO:B0031066 ! MKX_HUMAN relationship: location_of CCO:B0031067 ! IRX5_HUMAN relationship: location_of CCO:B0031069 ! IRX2_HUMAN relationship: location_of CCO:B0031070 ! IRX3_HUMAN relationship: location_of CCO:B0031071 ! IRX1_HUMAN relationship: location_of CCO:B0031337 ! LYN_HUMAN-Phosphotyrosine194 relationship: location_of CCO:B0031347 ! NDC80_HUMAN-Phosphoserine165 relationship: location_of CCO:B0031354 ! NEK2_HUMAN-Phosphoserine390 relationship: location_of CCO:B0031369 ! PTN6_HUMAN-Phosphotyrosine377 relationship: location_of CCO:B0031623 ! FX4L2_HUMAN relationship: location_of CCO:B0031625 ! FOXA3_HUMAN relationship: location_of CCO:B0031646 ! Q6S731_HUMAN relationship: location_of CCO:B0031650 ! Q6S729_HUMAN relationship: location_of CCO:B0031654 ! PAX6_HUMAN relationship: location_of CCO:B0031655 ! Q6S732_HUMAN relationship: location_of CCO:B0031656 ! Q6S728_HUMAN relationship: location_of CCO:B0031660 ! Q6S730_HUMAN relationship: location_of CCO:B0031661 ! PAX2_HUMAN relationship: location_of CCO:B0031669 ! RSPO1_HUMAN relationship: location_of CCO:B0031899 ! NARFL_HUMAN relationship: location_of CCO:B0032066 ! A8W2K5_HUMAN relationship: location_of CCO:B0032261 ! TEAD3_HUMAN relationship: location_of CCO:B0032263 ! Q7Z6U9_HUMAN relationship: location_of CCO:B0032264 ! Q96BK2_HUMAN relationship: location_of CCO:B0032266 ! Q8NEV5_HUMAN relationship: location_of CCO:B0032267 ! Q7Z6U7_HUMAN relationship: location_of CCO:B0032268 ! TEAD2_HUMAN relationship: location_of CCO:B0032269 ! Q6MZR9_HUMAN relationship: location_of CCO:B0032270 ! Q8NA25_HUMAN relationship: location_of CCO:B0032274 ! A4FUP2_HUMAN relationship: location_of CCO:B0032276 ! Q59EF3_HUMAN relationship: location_of CCO:B0032333 ! BTF3_HUMAN relationship: location_of CCO:B0032335 ! EID3_HUMAN relationship: location_of CCO:B0032363 ! ZN738_HUMAN relationship: location_of CCO:B0032380 ! NF2L1_HUMAN relationship: location_of CCO:B0032381 ! Q8NF22_HUMAN relationship: location_of CCO:B0032391 ! MTND_HUMAN relationship: location_of CCO:B0032462 ! CIRBP_HUMAN relationship: location_of CCO:B0032483 ! ME3L1_HUMAN relationship: location_of CCO:B0032489 ! MEIS1_HUMAN relationship: location_of CCO:B0032495 ! Q4G0U8_HUMAN relationship: location_of CCO:B0032498 ! A8MWD5_HUMAN relationship: location_of CCO:B0032499 ! MEIS2_HUMAN relationship: location_of CCO:B0032501 ! MEIS3_HUMAN relationship: location_of CCO:B0032504 ! ME3L2_HUMAN relationship: location_of CCO:B0032508 ! Q96DI2_HUMAN relationship: location_of CCO:B0032516 ! A8MUV4_HUMAN relationship: location_of CCO:B0032527 ! NKX28_HUMAN relationship: location_of CCO:B0032530 ! Q7KZF6_HUMAN relationship: location_of CCO:B0032532 ! Q5VZV8_HUMAN relationship: location_of CCO:B0032537 ! SP16H_HUMAN relationship: location_of CCO:B0032571 ! HOP2_HUMAN relationship: location_of CCO:B0032700 ! TGS1_HUMAN relationship: location_of CCO:B0032841 ! DBF4A_HUMAN-Phosphoserine539 relationship: location_of CCO:B0032858 ! TAF10_HUMAN-N6-methyllysine189 relationship: location_of CCO:B0032873 ! MND1_HUMAN relationship: location_of CCO:B0032975 ! TBPL2_HUMAN relationship: location_of CCO:B0032981 ! Q32MN6_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0033320 ! COF1_HUMAN relationship: location_of CCO:B0033365 ! LASS4_HUMAN relationship: location_of CCO:B0033366 ! LASS3_HUMAN relationship: location_of CCO:B0033369 ! LASS6_HUMAN relationship: location_of CCO:B0033374 ! Q5SZE3_HUMAN relationship: location_of CCO:B0033376 ! Q5SZE4_HUMAN relationship: location_of CCO:B0033381 ! Q5SZE2_HUMAN relationship: location_of CCO:B0033382 ! Q32M63_HUMAN relationship: location_of CCO:B0033383 ! A8K4M4_HUMAN relationship: location_of CCO:B0033384 ! Q49AQ3_HUMAN relationship: location_of CCO:B0033478 ! DBF4B_HUMAN relationship: location_of CCO:B0033618 ! Q2TAM6_HUMAN relationship: location_of CCO:B0033619 ! RUNX1_HUMAN relationship: location_of CCO:B0033620 ! Q5T802_HUMAN relationship: location_of CCO:B0033622 ! RUNX2_HUMAN relationship: location_of CCO:B0033733 ! MAFB_HUMAN relationship: location_of CCO:B0033734 ! MAF_HUMAN relationship: location_of CCO:B0034007 ! PSB7_HUMAN relationship: location_of CCO:B0034126 ! RARG_HUMAN relationship: location_of CCO:B0034177 ! Q14869_HUMAN relationship: location_of CCO:B0034353 ! SET1B_HUMAN relationship: location_of CCO:B0034583 ! B2L13_HUMAN-Phosphoserine420 relationship: location_of CCO:B0034607 ! BTAF1_HUMAN-Phosphoserine237 relationship: location_of CCO:B0034614 ! CCNL2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0034640 ! CDYL1_HUMAN-Phosphoserine201 relationship: location_of CCO:B0034661 ! CHD1_HUMAN-Phosphoserine1356 relationship: location_of CCO:B0034678 ! COF2_HUMAN-Phosphoserine3 relationship: location_of CCO:B0034696 ! DDX56_HUMAN-Phosphoserine126 relationship: location_of CCO:B0034711 ! DNMT1_HUMAN-Phosphoserine127 relationship: location_of CCO:B0034769 ! ETV6_HUMAN-Phosphoserine257 relationship: location_of CCO:B0034779 ! FABP4_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0034793 ! FOXA1_HUMAN-Phosphothreonine344 relationship: location_of CCO:B0034795 ! FOXC2_HUMAN-Phosphoserine232 relationship: location_of CCO:B0034799 ! FOXO1_HUMAN-Phosphoserine319 relationship: location_of CCO:B0034805 ! FOXO6_HUMAN-Phosphoserine184 relationship: location_of CCO:B0034822 ! G3BP1_HUMAN-Omega-N-methylated arginine460 relationship: location_of CCO:B0034845 ! GSK3B_HUMAN-Phosphoserine215 relationship: location_of CCO:B0034975 ! KAPCA_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0034978 ! KAPCB_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0034986 ! KCC1A_HUMAN-Phosphothreonine177 relationship: location_of CCO:B0034999 ! KCC4_HUMAN-Phosphoserine336 relationship: location_of CCO:B0035064 ! KPCG_HUMAN-Phosphoserine687 relationship: location_of CCO:B0035087 ! LANC2_HUMAN-Phosphotyrosine295 relationship: location_of CCO:B0035088 ! LASS2_HUMAN-Phosphoserine341 relationship: location_of CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: location_of CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: location_of CCO:B0035198 ! MK14_HUMAN-Phosphotyrosine182 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0035311 ! NTKL_HUMAN-Phosphoserine754 relationship: location_of CCO:B0035344 ! PCBP1_HUMAN-Phosphoserine190 relationship: location_of CCO:B0035392 ! PKN3_HUMAN-Phosphoserine544 relationship: location_of CCO:B0035406 ! POLH_HUMAN-Phosphoserine380 relationship: location_of CCO:B0035440 ! PRP4B_HUMAN-Phosphoserine20 relationship: location_of CCO:B0035471 ! PRP8_HUMAN-Phosphothreonine1318 relationship: location_of CCO:B0035477 ! PSA7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0035478 ! PSB1_HUMAN-Phosphotyrosine150 relationship: location_of CCO:B0035479 ! PSB2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035486 ! PSF2_HUMAN-Phosphothreonine180 relationship: location_of CCO:B0035500 ! RALY_HUMAN-Phosphoserine135 relationship: location_of CCO:B0035539 ! RD23B_HUMAN-Phosphoserine160 relationship: location_of CCO:B0035541 ! RFC3_HUMAN-Phosphoserine125 relationship: location_of CCO:B0035550 ! RGS12_HUMAN-Phosphoserine874 relationship: location_of CCO:B0035571 ! RHG07_HUMAN-Phosphoserine305 relationship: location_of CCO:B0035610 ! RUNX1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0035673 ! SOX11_HUMAN-Phosphoserine278 relationship: location_of CCO:B0035688 ! SRF_HUMAN-Phosphoserine253 relationship: location_of CCO:B0035692 ! SRPK2_HUMAN-Phosphotyrosine319 relationship: location_of CCO:B0035699 ! STAT6_HUMAN-Phosphotyrosine641 relationship: location_of CCO:B0035747 ! TB182_HUMAN-Phosphoserine1621 relationship: location_of CCO:B0035772 ! TERA_HUMAN-Phosphotyrosine805 relationship: location_of CCO:B0035773 ! TGFI1_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0035781 ! THOC4_HUMAN-Phosphoserine183 relationship: location_of CCO:B0035785 ! TISB_HUMAN-Phosphoserine54 relationship: location_of CCO:B0035820 ! U520_HUMAN-Phosphoserine1056 relationship: location_of CCO:B0035829 ! WDHD1_HUMAN-Phosphoserine374 relationship: location_of CCO:B0035836 ! XRCC1_HUMAN-Phosphoserine266 relationship: location_of CCO:B0035936 ! RNF8_HUMAN relationship: location_of CCO:B0035939 ! C8AP2_HUMAN relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0036005 ! FOXO4_HUMAN-Phosphoserine111 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0036139 ! SENP2_HUMAN relationship: location_of CCO:B0036272 ! ANM6_HUMAN relationship: location_of CCO:B0036523 ! ST17B_HUMAN relationship: location_of CCO:B0036627 ! RFC2_HUMAN relationship: location_of CCO:B0036665 ! Q1M183_HUMAN relationship: location_of CCO:B0036788 ! GBX2_HUMAN relationship: location_of CCO:B0036789 ! HXB8_HUMAN relationship: location_of CCO:B0036790 ! HXB5_HUMAN relationship: location_of CCO:B0036792 ! HXD4_HUMAN relationship: location_of CCO:B0036793 ! HXA7_HUMAN relationship: location_of CCO:B0036796 ! GBX1_HUMAN relationship: location_of CCO:B0036797 ! HXB4_HUMAN relationship: location_of CCO:B0036799 ! HXB7_HUMAN relationship: location_of CCO:B0036801 ! HXA5_HUMAN relationship: location_of CCO:B0036803 ! Q4VAU3_HUMAN relationship: location_of CCO:B0036805 ! PDX1_HUMAN relationship: location_of CCO:B0036807 ! CDX1_HUMAN relationship: location_of CCO:B0036808 ! Q86TF7_HUMAN relationship: location_of CCO:B0036810 ! GSX1_HUMAN relationship: location_of CCO:B0036813 ! HXC5_HUMAN relationship: location_of CCO:B0036814 ! HXA6_HUMAN relationship: location_of CCO:B0036816 ! HXC4_HUMAN relationship: location_of CCO:B0036818 ! HXC6_HUMAN relationship: location_of CCO:B0036820 ! Q9UD61_HUMAN relationship: location_of CCO:B0036821 ! HXD8_HUMAN relationship: location_of CCO:B0036822 ! O75805_HUMAN relationship: location_of CCO:B0036825 ! HXA4_HUMAN relationship: location_of CCO:B0036827 ! HXC8_HUMAN relationship: location_of CCO:B0036828 ! HXD9_HUMAN relationship: location_of CCO:B0036830 ! A8MYQ3_HUMAN relationship: location_of CCO:B0036831 ! A1L0T6_HUMAN relationship: location_of CCO:B0036832 ! GSX2_HUMAN relationship: location_of CCO:B0036835 ! Q16124_HUMAN relationship: location_of CCO:B0036838 ! HXB9_HUMAN relationship: location_of CCO:B0036929 ! A4D1Z4_HUMAN relationship: location_of CCO:B0036936 ! Q6FGL6_HUMAN relationship: location_of CCO:B0036939 ! HNF4G_HUMAN relationship: location_of CCO:B0037049 ! TRI66_HUMAN relationship: location_of CCO:B0037050 ! TRI33_HUMAN relationship: location_of CCO:B0037051 ! TIF1A_HUMAN relationship: location_of CCO:B0037089 ! ZN100_HUMAN relationship: location_of CCO:B0037090 ! ZN479_HUMAN relationship: location_of CCO:B0037092 ! ZN682_HUMAN relationship: location_of CCO:B0037093 ! ZN680_HUMAN relationship: location_of CCO:B0037094 ! Q6ZMM5_HUMAN relationship: location_of CCO:B0037096 ! ZN626_HUMAN relationship: location_of CCO:B0037097 ! Q96M04_HUMAN relationship: location_of CCO:B0037101 ! ZN431_HUMAN relationship: location_of CCO:B0037103 ! A4FVA7_HUMAN relationship: location_of CCO:B0037105 ! ZN273_HUMAN relationship: location_of CCO:B0037109 ! O95779_HUMAN relationship: location_of CCO:B0037110 ! ZNF92_HUMAN relationship: location_of CCO:B0037112 ! ZN430_HUMAN relationship: location_of CCO:B0037138 ! ZF64B_HUMAN relationship: location_of CCO:B0037139 ! ZF64A_HUMAN relationship: location_of CCO:B0037152 ! DUS16_HUMAN relationship: location_of CCO:B0037159 ! DUS8_HUMAN relationship: location_of CCO:B0037399 ! SOX17_HUMAN relationship: location_of CCO:B0037436 ! XPO5_HUMAN relationship: location_of CCO:B0037714 ! DNM3L_HUMAN relationship: location_of CCO:B0037765 ! OVL2L_HUMAN relationship: location_of CCO:B0037921 ! Q6RCM8_HUMAN relationship: location_of CCO:B0037922 ! A9LSF3_HUMAN relationship: location_of CCO:B0037924 ! IRF5_HUMAN relationship: location_of CCO:B0037929 ! IRF8_HUMAN relationship: location_of CCO:B0037930 ! Q1A7B4_HUMAN relationship: location_of CCO:B0037933 ! Q64GB2_HUMAN relationship: location_of CCO:B0037934 ! IRF9_HUMAN relationship: location_of CCO:B0037936 ! IRF6_HUMAN relationship: location_of CCO:B0037937 ! A4D1J8_HUMAN relationship: location_of CCO:B0037974 ! ZNF81_HUMAN relationship: location_of CCO:B0037975 ! ZN175_HUMAN relationship: location_of CCO:B0037981 ! DBX1_HUMAN relationship: location_of CCO:B0037983 ! DLX6_HUMAN relationship: location_of CCO:B0037984 ! DLX4_HUMAN relationship: location_of CCO:B0037985 ! BSH_HUMAN relationship: location_of CCO:B0037986 ! Q59HD6_HUMAN relationship: location_of CCO:B0037987 ! NKX63_HUMAN relationship: location_of CCO:B0037988 ! NKX62_HUMAN relationship: location_of CCO:B0037989 ! DLX5_HUMAN relationship: location_of CCO:B0037990 ! DLX3_HUMAN relationship: location_of CCO:B0037991 ! NKX61_HUMAN relationship: location_of CCO:B0038041 ! A2A2R7_HUMAN relationship: location_of CCO:B0038042 ! Q96SH0_HUMAN relationship: location_of CCO:B0038043 ! AP2E_HUMAN relationship: location_of CCO:B0038045 ! Q96SH1_HUMAN relationship: location_of CCO:B0038046 ! Q8N1C6_HUMAN relationship: location_of CCO:B0038047 ! Q5TAV5_HUMAN relationship: location_of CCO:B0038048 ! A8K557_HUMAN relationship: location_of CCO:B0038151 ! Q59FH9_HUMAN relationship: location_of CCO:B0038152 ! ZN446_HUMAN relationship: location_of CCO:B0038153 ! Q8NDK2_HUMAN relationship: location_of CCO:B0038197 ! PFD3_HUMAN relationship: location_of CCO:B0038317 ! TAF13_HUMAN relationship: location_of CCO:B0038370 ! IKZF3_HUMAN relationship: location_of CCO:B0038407 ! MD12L_HUMAN relationship: location_of CCO:B0038425 ! FOXI2_HUMAN relationship: location_of CCO:B0038585 ! Q7L3E5_HUMAN relationship: location_of CCO:B0038587 ! Q6ZSV8_HUMAN relationship: location_of CCO:B0038614 ! A6NJ87_HUMAN relationship: location_of CCO:B0038625 ! Q96M79_HUMAN relationship: location_of CCO:B0038627 ! ZNF19_HUMAN relationship: location_of CCO:B0038837 ! Q569H8_HUMAN relationship: location_of CCO:B0038840 ! Q9HCB2_HUMAN relationship: location_of CCO:B0038843 ! ERR2_HUMAN relationship: location_of CCO:B0038845 ! Q5F0P7_HUMAN relationship: location_of CCO:B0038846 ! ERR3_HUMAN relationship: location_of CCO:B0039094 ! ZN776_HUMAN relationship: location_of CCO:B0039095 ! ZN773_HUMAN relationship: location_of CCO:B0039097 ! A6NLI9_HUMAN relationship: location_of CCO:B0039099 ! A6NJK9_HUMAN relationship: location_of CCO:B0039101 ! ZN548_HUMAN relationship: location_of CCO:B0039102 ! ZN419_HUMAN relationship: location_of CCO:B0039103 ! A6NKR6_HUMAN relationship: location_of CCO:B0039104 ! ZN134_HUMAN relationship: location_of CCO:B0039105 ! ZN772_HUMAN relationship: location_of CCO:B0039107 ! A6NNZ3_HUMAN relationship: location_of CCO:B0039108 ! ZN211_HUMAN relationship: location_of CCO:B0039109 ! ZIK1_HUMAN relationship: location_of CCO:B0039113 ! Q59EG4_HUMAN relationship: location_of CCO:B0039114 ! ZN154_HUMAN relationship: location_of CCO:B0039118 ! Q2TAL7_HUMAN relationship: location_of CCO:B0039119 ! Q59FT8_HUMAN relationship: location_of CCO:B0039136 ! TIGD3_HUMAN relationship: location_of CCO:B0039142 ! FOXJ1_HUMAN relationship: location_of CCO:B0039318 ! AP2D_HUMAN-Phosphoserine239 relationship: location_of CCO:B0039332 ! BRPF1_HUMAN-Phosphoserine922 relationship: location_of CCO:B0039354 ! CDX2_HUMAN-Phosphoserine60 relationship: location_of CCO:B0039404 ! DNM3A_HUMAN-Phosphoserine105 relationship: location_of CCO:B0039424 ! FOXJ2_HUMAN-Phosphoserine161 relationship: location_of CCO:B0039427 ! FOXK1_HUMAN-Phosphoserine416 relationship: location_of CCO:B0039437 ! FOXP4_HUMAN-Phosphoserine360 relationship: location_of CCO:B0039454 ! HILS1_HUMAN-Phosphothreonine130 relationship: location_of CCO:B0039457 ! HNF4A_HUMAN-Phosphothreonine429 relationship: location_of CCO:B0039461 ! HXB6_HUMAN-Phosphoserine214 relationship: location_of CCO:B0039463 ! IF5A1_HUMAN-Blocked amino end (Ala)2 relationship: location_of CCO:B0039470 ! IKZF2_HUMAN-Phosphoserine174 relationship: location_of CCO:B0039472 ! IMA1_HUMAN-Phosphothreonine3 relationship: location_of CCO:B0039477 ! IRF7_HUMAN-Phosphoserine484 relationship: location_of CCO:B0039479 ! K1967_HUMAN-Phosphothreonine454 relationship: location_of CCO:B0039483 ! KI18A_HUMAN-Phosphoserine357 relationship: location_of CCO:B0039597 ! PRS10_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039600 ! PTBP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: location_of CCO:B0039636 ! RPB1_HUMAN-Phosphotyrosine1923 relationship: location_of CCO:B0039660 ! STK38_HUMAN-Phosphothreonine26 relationship: location_of CCO:B0039664 ! SYUA_HUMAN-Phosphoserine87 relationship: location_of CCO:B0039700 ! TTP_HUMAN-Phosphoserine323 relationship: location_of CCO:B0039718 ! ZN295_HUMAN-Phosphoserine411 relationship: location_of CCO:B0039725 ! ZN429_HUMAN-Phosphothreonine364 relationship: location_of CCO:B0039762 ! EXOS2_HUMAN-Phosphotyrosine46 relationship: location_of CCO:B0039765 ! FEN1_HUMAN-N6-acetyllysine377 relationship: location_of CCO:B0039769 ! UTP18_HUMAN-Phosphoserine210 relationship: location_of CCO:B0039862 ! KLK6_HUMAN relationship: location_of CCO:B0039905 ! TLE6_HUMAN relationship: location_of CCO:B0039910 ! A8MSP9_HUMAN relationship: location_of CCO:B0039938 ! TLE4_HUMAN-Phosphoserine265 relationship: location_of CCO:B0039945 ! CRBL2_HUMAN relationship: location_of CCO:B0039948 ! ZFP42_HUMAN relationship: location_of CCO:B0039949 ! FSD1_HUMAN relationship: location_of CCO:B0039950 ! DCC1_HUMAN relationship: location_of CCO:B0039955 ! NPAT_HUMAN-Phosphothreonine1270 relationship: location_of CCO:B0040022 ! JMY_HUMAN relationship: location_of CCO:B0040253 ! IMA4_HUMAN relationship: location_of CCO:B0040631 ! MDN1_HUMAN-Phosphoserine4538 relationship: location_of CCO:B0040683 ! GABP1_HUMAN relationship: location_of CCO:B0040686 ! NC2A_HUMAN relationship: location_of CCO:B0041126 ! BCL3_HUMAN-Phosphoserine394 relationship: location_of CCO:B0041132 ! CUX1_HUMAN-Phosphotyrosine1232 relationship: location_of CCO:B0041139 ! H4_HUMAN-Phosphoserine2 relationship: location_of CCO:B0041145 ! IKBA_HUMAN-Phosphoserine283 relationship: location_of CCO:B0041151 ! IKBB_HUMAN-Phosphoserine315 relationship: location_of CCO:B0041164 ! NEMO_HUMAN-Phosphoserine43 relationship: location_of CCO:B0041168 ! OGT1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041179 ! RELB_HUMAN-Phosphoserine573 relationship: location_of CCO:B0041199 ! STK6_HUMAN-Phosphothreonine287 relationship: location_of CCO:B0041207 ! TF65_HUMAN-N6-acetyllysine122 relationship: location_of CCO:B0041239 ! PSMD9_HUMAN relationship: location_of CCO:B0041241 ! CCDB1_HUMAN relationship: location_of CCO:B0041243 ! PSA2_HUMAN relationship: location_of CCO:B0041244 ! PSA4_HUMAN relationship: location_of CCO:B0041245 ! PSB4_HUMAN relationship: location_of CCO:B0041246 ! PRS7_HUMAN relationship: location_of CCO:B0041247 ! PRS6B_HUMAN relationship: location_of CCO:B0041249 ! HMGA2_HUMAN relationship: location_of CCO:B0041251 ! PSA6_HUMAN relationship: location_of CCO:B0041253 ! PRS8_HUMAN relationship: location_of CCO:B0041257 ! E4F1_HUMAN relationship: location_of CCO:B0041258 ! XAF1_HUMAN relationship: location_of CCO:B0041262 ! CTF8_HUMAN relationship: location_of CCO:B0041266 ! CINP_HUMAN relationship: location_of CCO:B0041267 ! DMTF1_HUMAN relationship: location_of CCO:B0041289 ! CNDH2_HUMAN-Phosphoserine200 relationship: location_of CCO:B0041315 ! PRS6A_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041339 ! RBX1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041548 ! SYF1_HUMAN relationship: location_of CCO:B0041576 ! WTIP_HUMAN relationship: location_of CCO:B0041586 ! B0ZTD4_HUMAN relationship: location_of CCO:B0041672 ! BNIPL_HUMAN relationship: location_of CCO:B0041843 ! TYY2_HUMAN relationship: location_of CCO:B0041948 ! NRK_HUMAN relationship: location_of CCO:B0041960 ! A2ABB0_HUMAN relationship: location_of CCO:B0042178 ! MAFG_HUMAN relationship: location_of CCO:B0042180 ! MAFF_HUMAN relationship: location_of CCO:B0042181 ! B0QY71_HUMAN relationship: location_of CCO:B0042182 ! B0QY70_HUMAN relationship: location_of CCO:B0042184 ! A8WFP5_HUMAN relationship: location_of CCO:B0042408 ! HIF3A_HUMAN relationship: location_of CCO:B0042415 ! A8MYV6_HUMAN relationship: location_of CCO:B0042816 ! T2H2L_HUMAN relationship: location_of CCO:B0043188 ! AF17_HUMAN-Phosphoserine378 relationship: location_of CCO:B0043260 ! EF1A2_HUMAN-N6,N6,N6-trimethyllysine165 relationship: location_of CCO:B0043273 ! 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HXC11_HUMAN relationship: location_of CCO:B0054463 ! RBM9_HUMAN relationship: location_of CCO:B0054468 ! ZBT43_HUMAN relationship: location_of CCO:B0054470 ! ZSC12_HUMAN relationship: location_of CCO:B0054471 ! PAX4_HUMAN relationship: location_of CCO:B0054473 ! ZN208_HUMAN relationship: location_of CCO:B0054474 ! ZN749_HUMAN relationship: location_of CCO:B0054475 ! HXA2_HUMAN relationship: location_of CCO:B0054476 ! HXA3_HUMAN relationship: location_of CCO:B0054477 ! O43372_HUMAN relationship: location_of CCO:B0054479 ! O43392_HUMAN relationship: location_of CCO:B0054483 ! KLF4_HUMAN relationship: location_of CCO:B0054488 ! SMAD6_HUMAN relationship: location_of CCO:B0054494 ! O43582_HUMAN relationship: location_of CCO:B0054495 ! HAIR_HUMAN relationship: location_of CCO:B0054497 ! RCL_HUMAN relationship: location_of CCO:B0054504 ! SNAI2_HUMAN relationship: location_of CCO:B0054509 ! ZN207_HUMAN relationship: location_of CCO:B0054510 ! TCF21_HUMAN relationship: location_of CCO:B0054512 ! TLX3_HUMAN relationship: location_of CCO:B0054519 ! TLX2_HUMAN relationship: location_of CCO:B0054521 ! DUX1_HUMAN relationship: location_of CCO:B0054523 ! ZF161_HUMAN relationship: location_of CCO:B0054524 ! ZNF73_HUMAN relationship: location_of CCO:B0054525 ! O43831_HUMAN relationship: location_of CCO:B0054531 ! AIRE_HUMAN relationship: location_of CCO:B0054539 ! ZN292_HUMAN relationship: location_of CCO:B0054540 ! ST18_HUMAN relationship: location_of CCO:B0054541 ! ZN862_HUMAN relationship: location_of CCO:B0054543 ! ZN500_HUMAN relationship: location_of CCO:B0054546 ! ZEB2_HUMAN relationship: location_of CCO:B0054547 ! MCM3A_HUMAN relationship: location_of CCO:B0054550 ! NUPR1_HUMAN relationship: location_of CCO:B0054551 ! NOBOX_HUMAN relationship: location_of CCO:B0054557 ! O60428_HUMAN relationship: location_of CCO:B0054566 ! CIDEA_HUMAN relationship: location_of CCO:B0054568 ! O60587_HUMAN relationship: location_of CCO:B0054572 ! LMX1B_HUMAN relationship: location_of CCO:B0054575 ! MUSC_HUMAN relationship: location_of CCO:B0054579 ! Z354A_HUMAN relationship: location_of CCO:B0054580 ! TBX19_HUMAN relationship: location_of CCO:B0054582 ! EDF1_HUMAN relationship: location_of CCO:B0054583 ! KIN17_HUMAN relationship: location_of CCO:B0054588 ! SHOX2_HUMAN relationship: location_of CCO:B0054590 ! TBL1X_HUMAN relationship: location_of CCO:B0054591 ! NOL3_HUMAN relationship: location_of CCO:B0054595 ! MITF_HUMAN relationship: location_of CCO:B0054601 ! MTG16_HUMAN relationship: location_of CCO:B0054603 ! ZN623_HUMAN relationship: location_of CCO:B0054606 ! CAND2_HUMAN relationship: location_of CCO:B0054611 ! CNOT3_HUMAN relationship: location_of CCO:B0054614 ! Z780A_HUMAN relationship: location_of CCO:B0054618 ! PDCD6_HUMAN relationship: location_of CCO:B0054620 ! ZN253_HUMAN relationship: location_of CCO:B0054622 ! PROP1_HUMAN relationship: location_of CCO:B0054624 ! PITX3_HUMAN relationship: location_of CCO:B0054629 ! TULP3_HUMAN relationship: location_of CCO:B0054631 ! DEAF1_HUMAN relationship: location_of CCO:B0054635 ! ZN254_HUMAN relationship: location_of CCO:B0054638 ! Z324A_HUMAN relationship: location_of CCO:B0054639 ! NR1I2_HUMAN relationship: location_of CCO:B0054645 ! DUX2_HUMAN relationship: location_of CCO:B0054646 ! HSBP1_HUMAN relationship: location_of CCO:B0054649 ! ZN821_HUMAN relationship: location_of CCO:B0054655 ! FOXH1_HUMAN relationship: location_of CCO:B0054656 ! GCM2_HUMAN relationship: location_of CCO:B0054658 ! PRDM1_HUMAN relationship: location_of CCO:B0054669 ! O75806_HUMAN relationship: location_of CCO:B0054671 ! ZN189_HUMAN relationship: location_of CCO:B0054673 ! KLF7_HUMAN relationship: location_of CCO:B0054683 ! SNPC5_HUMAN relationship: location_of CCO:B0054690 ! S14L2_HUMAN relationship: location_of CCO:B0054691 ! CIAO1_HUMAN relationship: location_of CCO:B0054707 ! TOX_HUMAN relationship: location_of CCO:B0054708 ! PRP6_HUMAN relationship: location_of CCO:B0054712 ! NFAT5_HUMAN relationship: location_of CCO:B0054714 ! CMTA2_HUMAN relationship: location_of CCO:B0054719 ! UBR5_HUMAN relationship: location_of CCO:B0054720 ! FSBP_HUMAN relationship: location_of CCO:B0054721 ! ALX3_HUMAN relationship: location_of CCO:B0054723 ! NKX22_HUMAN relationship: location_of CCO:B0054725 ! ZN202_HUMAN relationship: location_of CCO:B0054726 ! O95133_HUMAN relationship: location_of CCO:B0054731 ! ZFPL1_HUMAN relationship: location_of CCO:B0054735 ! ZN205_HUMAN relationship: location_of CCO:B0054738 ! VENTX_HUMAN relationship: location_of CCO:B0054739 ! SPDEF_HUMAN relationship: location_of CCO:B0054744 ! O95268_HUMAN relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0054749 ! SIX3_HUMAN relationship: location_of CCO:B0054761 ! TIAF1_HUMAN relationship: location_of CCO:B0054766 ! SIX6_HUMAN relationship: location_of CCO:B0054771 ! TTRAP_HUMAN relationship: location_of CCO:B0054772 ! KLF8_HUMAN relationship: location_of CCO:B0054774 ! ZBT11_HUMAN relationship: location_of CCO:B0054775 ! CNOT4_HUMAN relationship: location_of CCO:B0054778 ! FSTL3_HUMAN relationship: location_of CCO:B0054782 ! EYA4_HUMAN relationship: location_of CCO:B0054798 ! CLIC3_HUMAN relationship: location_of CCO:B0054805 ! CBX7_HUMAN relationship: location_of CCO:B0054806 ! EOMES_HUMAN relationship: location_of CCO:B0054814 ! MBD3_HUMAN relationship: location_of CCO:B0054815 ! TOP3B_HUMAN relationship: location_of CCO:B0054816 ! F107A_HUMAN relationship: location_of CCO:B0054819 ! HAND1_HUMAN relationship: location_of CCO:B0054833 ! FOS_HUMAN relationship: location_of CCO:B0054845 ! CALC_HUMAN relationship: location_of CCO:B0054882 ! TDT_HUMAN relationship: location_of CCO:B0054905 ! DPOLB_HUMAN relationship: location_of CCO:B0054918 ! ZFY_HUMAN relationship: location_of CCO:B0054921 ! TNR16_HUMAN relationship: location_of CCO:B0054922 ! GLI1_HUMAN relationship: location_of CCO:B0054925 ! MCR_HUMAN relationship: location_of CCO:B0054940 ! PO2F2_HUMAN relationship: location_of CCO:B0054943 ! STP1_HUMAN relationship: location_of CCO:B0054962 ! GLP1_HUMAN relationship: location_of CCO:B0054963 ! RHF2B_HUMAN relationship: location_of CCO:B0054965 ! GLI2_HUMAN relationship: location_of CCO:B0054966 ! HKR1_HUMAN relationship: location_of CCO:B0054967 ! ZSC22_HUMAN relationship: location_of CCO:B0054968 ! ZBT48_HUMAN relationship: location_of CCO:B0054971 ! GRAB_HUMAN relationship: location_of CCO:B0054978 ! THA_HUMAN relationship: location_of CCO:B0054979 ! THB_HUMAN relationship: location_of CCO:B0054992 ! VDR_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0054999 ! PTHR_HUMAN relationship: location_of CCO:B0055001 ! MYCL2_HUMAN relationship: location_of CCO:B0055002 ! GRAA_HUMAN relationship: location_of CCO:B0055004 ! SKI_HUMAN relationship: location_of CCO:B0055005 ! SKIL_HUMAN relationship: location_of CCO:B0055008 ! LYL1_HUMAN relationship: location_of CCO:B0055009 ! NR2C1_HUMAN relationship: location_of CCO:B0055012 ! MYF5_HUMAN relationship: location_of CCO:B0055017 ! ZNF35_HUMAN relationship: location_of CCO:B0055022 ! IRF2_HUMAN relationship: location_of CCO:B0055023 ! HCLS1_HUMAN relationship: location_of CCO:B0055026 ! HXB3_HUMAN relationship: location_of CCO:B0055028 ! HXB1_HUMAN relationship: location_of CCO:B0055031 ! MYOG_HUMAN relationship: location_of CCO:B0055041 ! ZN250_HUMAN relationship: location_of CCO:B0055043 ! PAX1_HUMAN relationship: location_of CCO:B0055045 ! GATA1_HUMAN relationship: location_of CCO:B0055050 ! ZN823_HUMAN relationship: location_of CCO:B0055062 ! ZFX_HUMAN relationship: location_of CCO:B0055063 ! ZNF12_HUMAN relationship: location_of CCO:B0055064 ! ZNF14_HUMAN relationship: location_of CCO:B0055065 ! ZN708_HUMAN relationship: location_of CCO:B0055066 ! ZNF16_HUMAN relationship: location_of CCO:B0055067 ! ZNF17_HUMAN relationship: location_of CCO:B0055068 ! ZNF18_HUMAN relationship: location_of CCO:B0055069 ! ZNF20_HUMAN relationship: location_of CCO:B0055070 ! ZN182_HUMAN relationship: location_of CCO:B0055071 ! ZNF22_HUMAN relationship: location_of CCO:B0055072 ! ZNF23_HUMAN relationship: location_of CCO:B0055074 ! ZNF25_HUMAN relationship: location_of CCO:B0055075 ! ZN37A_HUMAN relationship: location_of CCO:B0055076 ! ZNF28_HUMAN relationship: location_of CCO:B0055077 ! ZNF3_HUMAN relationship: location_of CCO:B0055078 ! ZNF43_HUMAN relationship: location_of CCO:B0055079 ! ZNF30_HUMAN relationship: location_of CCO:B0055080 ! ZNF32_HUMAN relationship: location_of CCO:B0055093 ! XBP1_HUMAN relationship: location_of CCO:B0055094 ! IBP3_HUMAN relationship: location_of CCO:B0055095 ! SPI1_HUMAN relationship: location_of CCO:B0055100 ! EGR1_HUMAN relationship: location_of CCO:B0055105 ! ATF1_HUMAN relationship: location_of CCO:B0055109 ! HME2_HUMAN relationship: location_of CCO:B0055121 ! NR1D1_HUMAN relationship: location_of CCO:B0055132 ! ZNF10_HUMAN relationship: location_of CCO:B0055146 ! USF1_HUMAN relationship: location_of CCO:B0055150 ! NR4A1_HUMAN relationship: location_of CCO:B0055156 ! MYF6_HUMAN relationship: location_of CCO:B0055163 ! PAX7_HUMAN relationship: location_of CCO:B0055164 ! PAX3_HUMAN relationship: location_of CCO:B0055165 ! GATA2_HUMAN relationship: location_of CCO:B0055166 ! GATA3_HUMAN relationship: location_of CCO:B0055169 ! ZBT25_HUMAN relationship: location_of CCO:B0055186 ! RBTN1_HUMAN relationship: location_of CCO:B0055194 ! APEX1_HUMAN relationship: location_of CCO:B0055200 ! ELK4_HUMAN relationship: location_of CCO:B0055202 ! HXD10_HUMAN relationship: location_of CCO:B0055203 ! MSX1_HUMAN relationship: location_of CCO:B0055206 ! MZF1_HUMAN relationship: location_of CCO:B0055209 ! T2EB_HUMAN relationship: location_of CCO:B0055212 ! RABP2_HUMAN relationship: location_of CCO:B0055213 ! JAD1A_HUMAN relationship: location_of CCO:B0055234 ! HXD3_HUMAN relationship: location_of CCO:B0055235 ! HXA10_HUMAN relationship: location_of CCO:B0055236 ! HXA9_HUMAN relationship: location_of CCO:B0055237 ! HXA11_HUMAN relationship: location_of CCO:B0055238 ! HXA13_HUMAN relationship: location_of CCO:B0055239 ! HXC9_HUMAN relationship: location_of CCO:B0055240 ! HXC12_HUMAN relationship: location_of CCO:B0055241 ! HXC13_HUMAN relationship: location_of CCO:B0055243 ! TLX1_HUMAN relationship: location_of CCO:B0055250 ! ARRB2_HUMAN relationship: location_of CCO:B0055254 ! OTX1_HUMAN relationship: location_of CCO:B0055255 ! OTX2_HUMAN relationship: location_of CCO:B0055266 ! DUT_HUMAN relationship: location_of CCO:B0055280 ! PCGF2_HUMAN relationship: location_of CCO:B0055283 ! ZN123_HUMAN relationship: location_of CCO:B0055284 ! ZN125_HUMAN relationship: location_of CCO:B0055285 ! ZN126_HUMAN relationship: location_of CCO:B0055291 ! HXD12_HUMAN relationship: location_of CCO:B0055292 ! HXD13_HUMAN relationship: location_of CCO:B0055294 ! MSX2_HUMAN relationship: location_of CCO:B0055301 ! SOX6_HUMAN relationship: location_of CCO:B0055302 ! ZNF93_HUMAN relationship: location_of CCO:B0055306 ! TCF7_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055309 ! ZNF76_HUMAN relationship: location_of CCO:B0055320 ! IF4A3_HUMAN relationship: location_of CCO:B0055324 ! CAPG_HUMAN relationship: location_of CCO:B0055329 ! PBX1_HUMAN relationship: location_of CCO:B0055330 ! PBX3_HUMAN relationship: location_of CCO:B0055331 ! ARL4A_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055334 ! ETV5_HUMAN relationship: location_of CCO:B0055345 ! ELK3_HUMAN relationship: location_of CCO:B0055356 ! NSG1_HUMAN relationship: location_of CCO:B0055362 ! ETV4_HUMAN relationship: location_of CCO:B0055369 ! GATA4_HUMAN relationship: location_of CCO:B0055370 ! NKX21_HUMAN relationship: location_of CCO:B0055402 ! RFX5_HUMAN relationship: location_of CCO:B0055403 ! SOX9_HUMAN relationship: location_of CCO:B0055411 ! LHX1_HUMAN relationship: location_of CCO:B0055412 ! TNNI2_HUMAN relationship: location_of CCO:B0055426 ! HXA1_HUMAN relationship: location_of CCO:B0055427 ! EVX1_HUMAN relationship: location_of CCO:B0055431 ! CEBPA_HUMAN relationship: location_of CCO:B0055432 ! CEBPD_HUMAN relationship: location_of CCO:B0055436 ! HINT1_HUMAN relationship: location_of CCO:B0055440 ! TAF6_HUMAN relationship: location_of CCO:B0055441 ! ZN165_HUMAN relationship: location_of CCO:B0055445 ! MEOX1_HUMAN relationship: location_of CCO:B0055451 ! LHX2_HUMAN relationship: location_of CCO:B0055452 ! ETV1_HUMAN relationship: location_of CCO:B0055453 ! ASCL1_HUMAN relationship: location_of CCO:B0055465 ! RORG_HUMAN relationship: location_of CCO:B0055466 ! ZNF80_HUMAN relationship: location_of CCO:B0055467 ! ZNF84_HUMAN relationship: location_of CCO:B0055478 ! ZN157_HUMAN relationship: location_of CCO:B0055481 ! ZNF41_HUMAN relationship: location_of CCO:B0055482 ! AFF3_HUMAN relationship: location_of CCO:B0055483 ! NR0B1_HUMAN relationship: location_of CCO:B0055487 ! NUPL_HUMAN relationship: location_of CCO:B0055490 ! ZN133_HUMAN relationship: location_of CCO:B0055491 ! ZN136_HUMAN relationship: location_of CCO:B0055492 ! ZN140_HUMAN relationship: location_of CCO:B0055493 ! ZN131_HUMAN relationship: location_of CCO:B0055494 ! ZN132_HUMAN relationship: location_of CCO:B0055495 ! ZN135_HUMAN relationship: location_of CCO:B0055496 ! ZN137_HUMAN relationship: location_of CCO:B0055497 ! ZN138_HUMAN relationship: location_of CCO:B0055499 ! ZN143_HUMAN relationship: location_of CCO:B0055506 ! NKX25_HUMAN relationship: location_of CCO:B0055507 ! LBX1_HUMAN relationship: location_of CCO:B0055511 ! RPAB4_HUMAN relationship: location_of CCO:B0055512 ! RCAN1_HUMAN relationship: location_of CCO:B0055518 ! NRL_HUMAN relationship: location_of CCO:B0055525 ! NR1H2_HUMAN relationship: location_of CCO:B0055526 ! BI1_HUMAN relationship: location_of CCO:B0055529 ! ELL_HUMAN relationship: location_of CCO:B0055535 ! PKNX1_HUMAN relationship: location_of CCO:B0055536 ! PAX9_HUMAN relationship: location_of CCO:B0055539 ! DLX1_HUMAN relationship: location_of CCO:B0055543 ! MAZ_HUMAN relationship: location_of CCO:B0055547 ! SOX10_HUMAN relationship: location_of CCO:B0055553 ! GSC_HUMAN relationship: location_of CCO:B0055556 ! PRD15_HUMAN relationship: location_of CCO:B0055557 ! SOX8_HUMAN relationship: location_of CCO:B0055561 ! SELB_HUMAN relationship: location_of CCO:B0055569 ! VSX2_HUMAN relationship: location_of CCO:B0055570 ! ZN121_HUMAN relationship: location_of CCO:B0055590 ! Z280A_HUMAN relationship: location_of CCO:B0055593 ! ZN445_HUMAN relationship: location_of CCO:B0055594 ! ELOF1_HUMAN relationship: location_of CCO:B0055605 ! CSN2_HUMAN relationship: location_of CCO:B0055608 ! HAND2_HUMAN relationship: location_of CCO:B0055611 ! PHS_HUMAN relationship: location_of CCO:B0055615 ! BTG1_HUMAN relationship: location_of CCO:B0055618 ! TBPL1_HUMAN relationship: location_of CCO:B0055622 ! RPAB5_HUMAN relationship: location_of CCO:B0055642 ! NKX32_HUMAN relationship: location_of CCO:B0055643 ! IRX6_HUMAN relationship: location_of CCO:B0055644 ! IRX4_HUMAN relationship: location_of CCO:B0055646 ! PO6F2_HUMAN relationship: location_of CCO:B0055650 ! ELF3_HUMAN relationship: location_of CCO:B0055654 ! SIM1_HUMAN relationship: location_of CCO:B0055656 ! SSBP2_HUMAN relationship: location_of CCO:B0055663 ! LBXCO_HUMAN relationship: location_of CCO:B0055673 ! ZXDB_HUMAN relationship: location_of CCO:B0055685 ! INSM1_HUMAN relationship: location_of CCO:B0055689 ! TSPY1_HUMAN relationship: location_of CCO:B0055695 ! SPIB_HUMAN relationship: location_of CCO:B0055703 ! MEF2B_HUMAN relationship: location_of CCO:B0055704 ! SP2_HUMAN relationship: location_of CCO:B0055708 ! ZNF45_HUMAN relationship: location_of CCO:B0055709 ! SP4_HUMAN relationship: location_of CCO:B0055711 ! HEN1_HUMAN relationship: location_of CCO:B0055712 ! HEN2_HUMAN relationship: location_of CCO:B0055716 ! RASF7_HUMAN relationship: location_of CCO:B0055722 ! PPARD_HUMAN relationship: location_of CCO:B0055724 ! PTHR1_HUMAN relationship: location_of CCO:B0055725 ! ERCC6_HUMAN relationship: location_of CCO:B0055726 ! EVX2_HUMAN relationship: location_of CCO:B0055727 ! ZNF85_HUMAN relationship: location_of CCO:B0055728 ! ZN117_HUMAN relationship: location_of CCO:B0055729 ! ZNF90_HUMAN relationship: location_of CCO:B0055730 ! ARI5A_HUMAN relationship: location_of CCO:B0055733 ! EMX1_HUMAN relationship: location_of CCO:B0055734 ! EMX2_HUMAN relationship: location_of CCO:B0055737 ! REL_HUMAN relationship: location_of CCO:B0055741 ! EGR4_HUMAN relationship: location_of CCO:B0055742 ! ZNF91_HUMAN relationship: location_of CCO:B0055743 ! ZBT16_HUMAN relationship: location_of CCO:B0055746 ! HME1_HUMAN relationship: location_of CCO:B0055750 ! MBTD1_HUMAN relationship: location_of CCO:B0055751 ! Q05BS4_HUMAN relationship: location_of CCO:B0055753 ! Q05BW2_HUMAN relationship: location_of CCO:B0055761 ! Q05D88_HUMAN relationship: location_of CCO:B0055762 ! Q05DA6_HUMAN relationship: location_of CCO:B0055763 ! Q05DF4_HUMAN relationship: location_of CCO:B0055767 ! SUH_HUMAN relationship: location_of CCO:B0055769 ! MTG8_HUMAN relationship: location_of CCO:B0055771 ! PAX8_HUMAN relationship: location_of CCO:B0055772 ! ZN33A_HUMAN relationship: location_of CCO:B0055773 ! ZN33B_HUMAN relationship: location_of CCO:B0055775 ! PRDX1_HUMAN relationship: location_of CCO:B0055776 ! EGR3_HUMAN relationship: location_of CCO:B0055778 ! Q06DQ3_HUMAN relationship: location_of CCO:B0055786 ! PPARA_HUMAN relationship: location_of CCO:B0055798 ! ZN844_HUMAN relationship: location_of CCO:B0055803 ! 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PKNX2_HUMAN relationship: location_of CCO:B0058263 ! Q96KW0_HUMAN relationship: location_of CCO:B0058272 ! HSFY1_HUMAN relationship: location_of CCO:B0058273 ! Q96LU8_HUMAN relationship: location_of CCO:B0058274 ! Z354B_HUMAN relationship: location_of CCO:B0058276 ! BINCA_HUMAN relationship: location_of CCO:B0058277 ! ZN323_HUMAN relationship: location_of CCO:B0058278 ! ZN597_HUMAN relationship: location_of CCO:B0058283 ! DMRTB_HUMAN relationship: location_of CCO:B0058285 ! Q96MC1_HUMAN relationship: location_of CCO:B0058286 ! Q96ME4_HUMAN relationship: location_of CCO:B0058287 ! ZN512_HUMAN relationship: location_of CCO:B0058289 ! Q96ML5_HUMAN relationship: location_of CCO:B0058290 ! Q96MM8_HUMAN relationship: location_of CCO:B0058291 ! ZN488_HUMAN relationship: location_of CCO:B0058292 ! ZN560_HUMAN relationship: location_of CCO:B0058293 ! ZN778_HUMAN relationship: location_of CCO:B0058295 ! TIGD1_HUMAN relationship: location_of CCO:B0058296 ! ZNF48_HUMAN relationship: location_of CCO:B0058298 ! ZN681_HUMAN relationship: location_of CCO:B0058299 ! ZN578_HUMAN relationship: location_of CCO:B0058301 ! ZN641_HUMAN relationship: location_of CCO:B0058302 ! ZN396_HUMAN relationship: location_of CCO:B0058303 ! ZN583_HUMAN relationship: location_of CCO:B0058304 ! ZN558_HUMAN relationship: location_of CCO:B0058306 ! ZN570_HUMAN relationship: location_of CCO:B0058307 ! ZFP3_HUMAN relationship: location_of CCO:B0058308 ! NDF6_HUMAN relationship: location_of CCO:B0058309 ! ZN599_HUMAN relationship: location_of CCO:B0058310 ! TOX2_HUMAN relationship: location_of CCO:B0058311 ! AIFM3_HUMAN relationship: location_of CCO:B0058314 ! DACH2_HUMAN relationship: location_of CCO:B0058315 ! FOXN4_HUMAN relationship: location_of CCO:B0058325 ! NECA3_HUMAN relationship: location_of CCO:B0058332 ! ZIM3_HUMAN relationship: location_of CCO:B0058338 ! Z385A_HUMAN relationship: location_of CCO:B0058342 ! ZN317_HUMAN relationship: location_of CCO:B0058343 ! DUX5_HUMAN relationship: location_of CCO:B0058344 ! DUX3_HUMAN relationship: location_of CCO:B0058345 ! QKI_HUMAN relationship: location_of CCO:B0058348 ! FMNL2_HUMAN relationship: location_of CCO:B0058354 ! Q96QH7_HUMAN relationship: location_of CCO:B0058357 ! ARX_HUMAN relationship: location_of CCO:B0058376 ! NR1H4_HUMAN relationship: location_of CCO:B0058380 ! FER3L_HUMAN relationship: location_of CCO:B0058386 ! WRIP1_HUMAN relationship: location_of CCO:B0058387 ! AXUD1_HUMAN relationship: location_of CCO:B0058389 ! PKHF1_HUMAN relationship: location_of CCO:B0058390 ! DMTA2_HUMAN relationship: location_of CCO:B0058393 ! ZN587_HUMAN relationship: location_of CCO:B0058394 ! ATOH8_HUMAN relationship: location_of CCO:B0058395 ! ZN382_HUMAN relationship: location_of CCO:B0058397 ! ZSC10_HUMAN relationship: location_of CCO:B0058404 ! INSM2_HUMAN relationship: location_of CCO:B0058405 ! Q96TB0_HUMAN relationship: location_of CCO:B0058411 ! Q99419_HUMAN relationship: location_of CCO:B0058412 ! PHX2B_HUMAN relationship: location_of CCO:B0058414 ! NOTC4_HUMAN relationship: location_of CCO:B0058416 ! PFD5_HUMAN relationship: location_of CCO:B0058419 ! EYA1_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058427 ! FEV_HUMAN relationship: location_of CCO:B0058429 ! TBX5_HUMAN relationship: location_of CCO:B0058431 ! KLF6_HUMAN relationship: location_of CCO:B0058437 ! ZN184_HUMAN relationship: location_of CCO:B0058441 ! PITX2_HUMAN relationship: location_of CCO:B0058447 ! ROAA_HUMAN relationship: location_of CCO:B0058451 ! NPAS1_HUMAN relationship: location_of CCO:B0058455 ! NKX31_HUMAN relationship: location_of CCO:B0058456 ! PRRX2_HUMAN relationship: location_of CCO:B0058461 ! ASCL2_HUMAN relationship: location_of CCO:B0058462 ! BAG1_HUMAN relationship: location_of CCO:B0058463 ! ATF6B_HUMAN relationship: location_of CCO:B0058464 ! 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ZN577_HUMAN relationship: location_of CCO:B0058507 ! PCGF1_HUMAN relationship: location_of CCO:B0058513 ! SOX7_HUMAN relationship: location_of CCO:B0058514 ! MTA3_HUMAN relationship: location_of CCO:B0058516 ! ZN692_HUMAN relationship: location_of CCO:B0058520 ! ZSA5A_HUMAN relationship: location_of CCO:B0058524 ! ZN426_HUMAN relationship: location_of CCO:B0058527 ! PHF20_HUMAN relationship: location_of CCO:B0058529 ! MAD3_HUMAN relationship: location_of CCO:B0058531 ! REPI1_HUMAN relationship: location_of CCO:B0058534 ! ZN416_HUMAN relationship: location_of CCO:B0058536 ! CDCA7_HUMAN relationship: location_of CCO:B0058542 ! SCRT1_HUMAN relationship: location_of CCO:B0058543 ! GATA5_HUMAN relationship: location_of CCO:B0058546 ! ZN471_HUMAN relationship: location_of CCO:B0058547 ! SALL3_HUMAN relationship: location_of CCO:B0058552 ! CECR2_HUMAN relationship: location_of CCO:B0058553 ! SPZ1_HUMAN relationship: location_of CCO:B0058557 ! KLF16_HUMAN relationship: location_of CCO:B0058564 ! AN30A_HUMAN relationship: location_of CCO:B0058569 ! HDAC8_HUMAN relationship: location_of CCO:B0058576 ! HES7_HUMAN relationship: location_of CCO:B0058579 ! IKBZ_HUMAN relationship: location_of CCO:B0058580 ! ZN341_HUMAN relationship: location_of CCO:B0058582 ! PBX4_HUMAN relationship: location_of CCO:B0058584 ! TRI55_HUMAN relationship: location_of CCO:B0058585 ! BACH2_HUMAN relationship: location_of CCO:B0058592 ! NSD3_HUMAN relationship: location_of CCO:B0058596 ! Q9BZD1_HUMAN relationship: location_of CCO:B0058597 ! BARH1_HUMAN relationship: location_of CCO:B0058599 ! Q9BZI2_HUMAN relationship: location_of CCO:B0058606 ! FOXP3_HUMAN relationship: location_of CCO:B0058608 ! PO5L3_HUMAN relationship: location_of CCO:B0058609 ! PO5L4_HUMAN relationship: location_of CCO:B0058612 ! API5_HUMAN relationship: location_of CCO:B0058613 ! NALP1_HUMAN relationship: location_of CCO:B0058615 ! ZFHX2_HUMAN relationship: location_of CCO:B0058616 ! Z518B_HUMAN relationship: location_of CCO:B0058617 ! ASXL3_HUMAN relationship: location_of CCO:B0058618 ! ZN436_HUMAN relationship: location_of CCO:B0058619 ! ZN407_HUMAN relationship: location_of CCO:B0058621 ! BHLH3_HUMAN relationship: location_of CCO:B0058622 ! BC11B_HUMAN relationship: location_of CCO:B0058628 ! WDR12_HUMAN relationship: location_of CCO:B0058634 ! REXO4_HUMAN relationship: location_of CCO:B0058637 ! PEG3_HUMAN relationship: location_of CCO:B0058639 ! PRD14_HUMAN relationship: location_of CCO:B0058641 ! ZN350_HUMAN relationship: location_of CCO:B0058645 ! HXD1_HUMAN relationship: location_of CCO:B0058654 ! ZN700_HUMAN relationship: location_of CCO:B0058656 ! PHS2_HUMAN relationship: location_of CCO:B0058659 ! GZF1_HUMAN relationship: location_of CCO:B0058660 ! ALX4_HUMAN relationship: location_of CCO:B0058661 ! CSRN2_HUMAN relationship: location_of CCO:B0058680 ! LHX5_HUMAN relationship: location_of CCO:B0058684 ! TARA_HUMAN relationship: location_of CCO:B0058688 ! ADNP_HUMAN relationship: location_of CCO:B0058693 ! LITFL_HUMAN relationship: location_of CCO:B0058702 ! TCAL2_HUMAN relationship: location_of CCO:B0058709 ! JHD3C_HUMAN relationship: location_of CCO:B0058714 ! Q9H4A8_HUMAN relationship: location_of CCO:B0058718 ! PRD13_HUMAN relationship: location_of CCO:B0058719 ! PRD12_HUMAN relationship: location_of CCO:B0058720 ! COE3_HUMAN relationship: location_of CCO:B0058724 ! DUS21_HUMAN relationship: location_of CCO:B0058727 ! ZBTB3_HUMAN relationship: location_of CCO:B0058729 ! IKZF5_HUMAN relationship: location_of CCO:B0058730 ! ZN576_HUMAN relationship: location_of CCO:B0058735 ! Q9H6M4_HUMAN relationship: location_of CCO:B0058737 ! ZN552_HUMAN relationship: location_of CCO:B0058744 ! ZN442_HUMAN relationship: location_of CCO:B0058746 ! ZN703_HUMAN relationship: location_of CCO:B0058747 ! ZN696_HUMAN relationship: location_of CCO:B0058750 ! ZN395_HUMAN relationship: location_of CCO:B0058751 ! Q9H8R0_HUMAN relationship: location_of CCO:B0058752 ! Q9H942_HUMAN relationship: location_of CCO:B0058753 ! ZN702_HUMAN relationship: location_of CCO:B0058754 ! ZN408_HUMAN relationship: location_of CCO:B0058756 ! NANOG_HUMAN relationship: location_of CCO:B0058758 ! LN28A_HUMAN relationship: location_of CCO:B0058759 ! ZMAT3_HUMAN relationship: location_of CCO:B0058761 ! ZN556_HUMAN relationship: location_of CCO:B0058764 ! COE2_HUMAN relationship: location_of CCO:B0058768 ! SMUF2_HUMAN relationship: location_of CCO:B0058771 ! BRF2_HUMAN relationship: location_of CCO:B0058772 ! PRD16_HUMAN relationship: location_of CCO:B0058774 ! SEBOX_HUMAN relationship: location_of CCO:B0058777 ! SP110_HUMAN relationship: location_of CCO:B0058778 ! ELL3_HUMAN relationship: location_of CCO:B0058779 ! PIDD_HUMAN relationship: location_of CCO:B0058781 ! RRAGC_HUMAN relationship: location_of CCO:B0058782 ! PATZ1_HUMAN relationship: location_of CCO:B0058790 ! ZN287_HUMAN relationship: location_of CCO:B0058791 ! Z286A_HUMAN relationship: location_of CCO:B0058792 ! BARX1_HUMAN relationship: location_of CCO:B0058796 ! GPBL1_HUMAN relationship: location_of CCO:B0058799 ! ZBT20_HUMAN relationship: location_of CCO:B0058801 ! HES4_HUMAN relationship: location_of CCO:B0058807 ! NCM_HUMAN relationship: location_of CCO:B0058809 ! ZBT26_HUMAN relationship: location_of CCO:B0058811 ! ZFP14_HUMAN relationship: location_of CCO:B0058819 ! PREB_HUMAN relationship: location_of CCO:B0058820 ! ZN304_HUMAN relationship: location_of CCO:B0058821 ! Q9HCY4_HUMAN relationship: location_of CCO:B0058822 ! ZN334_HUMAN relationship: location_of CCO:B0058827 ! Q9HD74_HUMAN relationship: location_of CCO:B0058828 ! NDF4_HUMAN relationship: location_of CCO:B0058830 ! HMX1_HUMAN relationship: location_of CCO:B0058834 ! GCM1_HUMAN relationship: location_of CCO:B0058843 ! ENY2_HUMAN relationship: location_of CCO:B0058847 ! MYNN_HUMAN relationship: location_of CCO:B0058848 ! SIX2_HUMAN relationship: location_of CCO:B0058854 ! NOX4_HUMAN relationship: location_of CCO:B0058855 ! PNRC2_HUMAN relationship: location_of CCO:B0058857 ! SCRT2_HUMAN relationship: location_of CCO:B0058860 ! ASCL3_HUMAN relationship: location_of CCO:B0058863 ! LHX9_HUMAN relationship: location_of CCO:B0058865 ! HEYL_HUMAN relationship: location_of CCO:B0058866 ! A1CF_HUMAN relationship: location_of CCO:B0058868 ! DMRT3_HUMAN relationship: location_of CCO:B0058870 ! Q9NQR6_HUMAN relationship: location_of CCO:B0058874 ! PRDM9_HUMAN relationship: location_of CCO:B0058875 ! PRDM8_HUMAN relationship: location_of CCO:B0058876 ! PRDM7_HUMAN relationship: location_of CCO:B0058878 ! PRDM6_HUMAN relationship: location_of CCO:B0058879 ! PRDM5_HUMAN relationship: location_of CCO:B0058880 ! ZN331_HUMAN relationship: location_of CCO:B0058881 ! ZNF71_HUMAN relationship: location_of CCO:B0058882 ! ZN302_HUMAN relationship: location_of CCO:B0058887 ! BATF3_HUMAN relationship: location_of CCO:B0058890 ! S2A4R_HUMAN relationship: location_of CCO:B0058898 ! TSH2_HUMAN relationship: location_of CCO:B0058899 ! SH2B1_HUMAN relationship: location_of CCO:B0058906 ! DUS22_HUMAN relationship: location_of CCO:B0058917 ! ZN275_HUMAN relationship: location_of CCO:B0058921 ! ZN834_HUMAN relationship: location_of CCO:B0058926 ! ZFP57_HUMAN relationship: location_of CCO:B0058929 ! ZN701_HUMAN relationship: location_of CCO:B0058932 ! ASF1B_HUMAN relationship: location_of CCO:B0058935 ! ZN358_HUMAN relationship: location_of CCO:B0058937 ! Q9NWF0_HUMAN relationship: location_of CCO:B0058941 ! HIF1N_HUMAN relationship: location_of CCO:B0058947 ! SOLH2_HUMAN relationship: location_of CCO:B0058950 ! ZN434_HUMAN relationship: location_of CCO:B0058956 ! ZN586_HUMAN relationship: location_of CCO:B0058958 ! BARH2_HUMAN relationship: location_of CCO:B0058959 ! Q9NY94_HUMAN relationship: location_of CCO:B0058960 ! DACT1_HUMAN relationship: location_of CCO:B0058973 ! ZN226_HUMAN relationship: location_of CCO:B0058985 ! RBAK_HUMAN relationship: location_of CCO:B0058991 ! EHF_HUMAN relationship: location_of CCO:B0058992 ! SMAL1_HUMAN relationship: location_of CCO:B0058997 ! GRHL1_HUMAN relationship: location_of CCO:B0058998 ! TF2L1_HUMAN relationship: location_of CCO:B0058999 ! UBIP1_HUMAN relationship: location_of CCO:B0059000 ! IF2B1_HUMAN relationship: location_of CCO:B0059013 ! VSX1_HUMAN relationship: location_of CCO:B0059018 ! LMCD1_HUMAN relationship: location_of CCO:B0059021 ! ZIM2_HUMAN relationship: location_of CCO:B0059023 ! CHMP5_HUMAN relationship: location_of CCO:B0059025 ! TAP26_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0059030 ! ZN167_HUMAN relationship: location_of CCO:B0059032 ! H2AW_HUMAN relationship: location_of CCO:B0059043 ! MDFIC_HUMAN relationship: location_of CCO:B0059046 ! ZBTB4_HUMAN relationship: location_of CCO:B0059049 ! POGK_HUMAN relationship: location_of CCO:B0059052 ! ZFAT_HUMAN relationship: location_of CCO:B0059053 ! ZN492_HUMAN relationship: location_of CCO:B0059056 ! CHD7_HUMAN relationship: location_of CCO:B0059057 ! ZN319_HUMAN relationship: location_of CCO:B0059067 ! HSFX1_HUMAN relationship: location_of CCO:B0059071 ! RBX2_HUMAN relationship: location_of CCO:B0059073 ! RBPJL_HUMAN relationship: location_of CCO:B0059081 ! HEY2_HUMAN relationship: location_of CCO:B0059089 ! HESX1_HUMAN relationship: location_of CCO:B0059090 ! DUX4_HUMAN relationship: location_of CCO:B0059092 ! REV1_HUMAN relationship: location_of CCO:B0059093 ! Q9UC05_HUMAN relationship: location_of CCO:B0059094 ! ZNF70_HUMAN relationship: location_of CCO:B0059095 ! ZNF69_HUMAN relationship: location_of CCO:B0059096 ! Q9UCY6_HUMAN relationship: location_of CCO:B0059097 ! Q9UD04_HUMAN relationship: location_of CCO:B0059098 ! NKX12_HUMAN relationship: location_of CCO:B0059104 ! ZN212_HUMAN relationship: location_of CCO:B0059105 ! ZN282_HUMAN relationship: location_of CCO:B0059106 ! MALT1_HUMAN relationship: location_of CCO:B0059109 ! ZN629_HUMAN relationship: location_of CCO:B0059114 ! ZBT47_HUMAN relationship: location_of CCO:B0059117 ! CGBP1_HUMAN relationship: location_of CCO:B0059124 ! JAD1B_HUMAN relationship: location_of CCO:B0059127 ! HM2L1_HUMAN relationship: location_of CCO:B0059140 ! IP6K2_HUMAN relationship: location_of CCO:B0059143 ! NUFP1_HUMAN relationship: location_of CCO:B0059144 ! DDX25_HUMAN relationship: location_of CCO:B0059158 ! ZN230_HUMAN relationship: location_of CCO:B0059162 ! KLF15_HUMAN relationship: location_of CCO:B0059163 ! ZN107_HUMAN relationship: location_of CCO:B0059164 ! SIX4_HUMAN relationship: location_of CCO:B0059166 ! VAX2_HUMAN relationship: location_of CCO:B0059172 ! ZN643_HUMAN relationship: location_of CCO:B0059174 ! SALL4_HUMAN relationship: location_of CCO:B0059175 ! LEF1_HUMAN relationship: location_of CCO:B0059176 ! ZF112_HUMAN relationship: location_of CCO:B0059178 ! ZN229_HUMAN relationship: location_of CCO:B0059180 ! SRTD3_HUMAN relationship: location_of CCO:B0059184 ! ZN223_HUMAN relationship: location_of CCO:B0059185 ! ZN222_HUMAN relationship: location_of CCO:B0059186 ! ZN221_HUMAN relationship: location_of CCO:B0059191 ! GMEB2_HUMAN relationship: location_of CCO:B0059197 ! PRDM4_HUMAN relationship: location_of CCO:B0059208 ! ELF5_HUMAN relationship: location_of CCO:B0059213 ! TBX21_HUMAN relationship: location_of CCO:B0059216 ! ZN236_HUMAN relationship: location_of CCO:B0059217 ! TCFL5_HUMAN relationship: location_of CCO:B0059218 ! ZN215_HUMAN relationship: location_of CCO:B0059219 ! ZN214_HUMAN relationship: location_of CCO:B0059222 ! ZN777_HUMAN relationship: location_of CCO:B0059227 ! ZMIZ1_HUMAN relationship: location_of CCO:B0059229 ! ZN490_HUMAN relationship: location_of CCO:B0059230 ! YETS2_HUMAN relationship: location_of CCO:B0059235 ! ABT1_HUMAN relationship: location_of CCO:B0059242 ! PHTF1_HUMAN relationship: location_of CCO:B0059249 ! POLI_HUMAN relationship: location_of CCO:B0059253 ! TF2AY_HUMAN relationship: location_of CCO:B0059255 ! PPIE_HUMAN relationship: location_of CCO:B0059257 ! ZN232_HUMAN relationship: location_of CCO:B0059261 ! LHX61_HUMAN relationship: location_of CCO:B0059264 ! TRI35_HUMAN relationship: location_of CCO:B0059266 ! SMG5_HUMAN relationship: location_of CCO:B0059267 ! ZN409_HUMAN relationship: location_of CCO:B0059269 ! TRAK1_HUMAN relationship: location_of CCO:B0059279 ! Q9UQD2_HUMAN relationship: location_of CCO:B0059298 ! INVS_HUMAN relationship: location_of CCO:B0059302 ! CK009_HUMAN relationship: location_of CCO:B0059303 ! CARD8_HUMAN relationship: location_of CCO:B0059304 ! ZFP30_HUMAN relationship: location_of CCO:B0059306 ! ZN510_HUMAN relationship: location_of CCO:B0059309 ! ZBTB1_HUMAN relationship: location_of CCO:B0059310 ! ZKSC5_HUMAN relationship: location_of CCO:B0059311 ! ZN835_HUMAN relationship: location_of CCO:B0059312 ! ZN256_HUMAN relationship: location_of CCO:B0059313 ! ZN257_HUMAN relationship: location_of CCO:B0059319 ! RX_HUMAN relationship: location_of CCO:B0059323 ! RPC10_HUMAN relationship: location_of CCO:B0059324 ! ZBT32_HUMAN relationship: location_of CCO:B0059326 ! KLF13_HUMAN relationship: location_of CCO:B0059334 ! UTP11_HUMAN relationship: location_of CCO:B0059336 ! HDGR3_HUMAN relationship: location_of CCO:B0059339 ! CBY1_HUMAN relationship: location_of CCO:B0059340 ! ZN337_HUMAN relationship: location_of CCO:B0059345 ! PYGO1_HUMAN relationship: location_of CCO:B0059348 ! ZN711_HUMAN relationship: location_of CCO:B0059349 ! DYR1B_HUMAN relationship: location_of CCO:B0059352 ! LMBL1_HUMAN relationship: location_of CCO:B0059354 ! Q9Y4A3_HUMAN relationship: location_of CCO:B0059355 ! NF2L3_HUMAN relationship: location_of CCO:B0059357 ! JHD2A_HUMAN relationship: location_of CCO:B0059366 ! KLF12_HUMAN relationship: location_of CCO:B0059368 ! HES2_HUMAN relationship: location_of CCO:B0059375 ! ZSC21_HUMAN relationship: location_of CCO:B0059378 ! HEY1_HUMAN relationship: location_of CCO:B0059383 ! DMRT2_HUMAN relationship: location_of CCO:B0059384 ! DMRT1_HUMAN relationship: location_of CCO:B0059388 ! KLF2_HUMAN relationship: location_of CCO:B0059391 ! NR2E3_HUMAN relationship: location_of CCO:B0059395 ! ETV7_HUMAN relationship: location_of CCO:B0059400 ! MORF4_HUMAN relationship: location_of CCO:B0059407 ! CABIN_HUMAN relationship: location_of CCO:B0059410 ! IF2B2_HUMAN relationship: location_of CCO:B0059415 ! Z780B_HUMAN relationship: location_of CCO:B0059416 ! Q9Y6T0_HUMAN relationship: location_of CCO:B0061983 ! RFX6_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0061986 ! FOX1A_HUMAN relationship: location_of CCO:B0061990 ! IN80B_HUMAN relationship: location_of CCO:B0062772 ! DD19A_HUMAN relationship: location_of CCO:B0062775 ! TESC_HUMAN relationship: location_of CCO:B0062780 ! NUP54_HUMAN relationship: location_of CCO:B0062792 ! TSNAX_HUMAN relationship: location_of CCO:B0062794 ! TRI32_HUMAN relationship: location_of CCO:B0062803 ! APEX2_HUMAN relationship: location_of CCO:B0062804 ! S100P_HUMAN relationship: location_of CCO:B0062805 ! APBP2_HUMAN relationship: location_of CCO:B0062808 ! SPAT2_HUMAN relationship: location_of CCO:B0062826 ! DPY30_HUMAN relationship: location_of CCO:B0062834 ! DPPA4_HUMAN relationship: location_of CCO:B0062841 ! DDX17_HUMAN relationship: location_of CCO:B0062848 ! NO40_HUMAN relationship: location_of CCO:B0062853 ! GNL3L_HUMAN relationship: location_of CCO:B0062857 ! MGN2_HUMAN relationship: location_of CCO:B0062868 ! DGC6L_HUMAN relationship: location_of CCO:B0062870 ! IPO13_HUMAN relationship: location_of CCO:B0062872 ! IMP3_HUMAN relationship: location_of CCO:B0062875 ! NOL4_HUMAN relationship: location_of CCO:B0062880 ! THAP1_HUMAN relationship: location_of CCO:B0062890 ! CPSF7_HUMAN relationship: location_of CCO:B0062892 ! RO52_HUMAN relationship: location_of CCO:B0062897 ! DDX39_HUMAN relationship: location_of CCO:B0062909 ! RLP24_HUMAN relationship: location_of CCO:B0062942 ! CSR2B_HUMAN relationship: location_of CCO:B0062946 ! THEG_HUMAN relationship: location_of CCO:B0062957 ! PHLA1_HUMAN relationship: location_of CCO:B0062979 ! GEMI5_HUMAN relationship: location_of CCO:B0063001 ! SUMO2_HUMAN relationship: location_of CCO:B0063002 ! MBD4_HUMAN relationship: location_of CCO:B0063003 ! SNRPA_HUMAN relationship: location_of CCO:B0063004 ! RANB9_HUMAN relationship: location_of CCO:B0063011 ! U2AF2_HUMAN relationship: location_of CCO:B0063016 ! NCBP2_HUMAN relationship: location_of CCO:B0063018 ! CDR2_HUMAN relationship: location_of CCO:B0063027 ! ZRAN1_HUMAN relationship: location_of CCO:B0063028 ! OIP5_HUMAN relationship: location_of CCO:B0063034 ! RRAGD_HUMAN relationship: location_of CCO:B0063074 ! UBP18_HUMAN relationship: location_of CCO:B0063112 ! UXT_HUMAN relationship: location_of CCO:B0063118 ! LEG7_HUMAN relationship: location_of CCO:B0063122 ! U5S1_HUMAN relationship: location_of CCO:B0063136 ! PDCD2_HUMAN relationship: location_of CCO:B0063138 ! RPAB3_HUMAN relationship: location_of CCO:B0063156 ! SRBS2_HUMAN relationship: location_of CCO:B0063157 ! LSM4_HUMAN relationship: location_of CCO:B0063163 ! ZN330_HUMAN relationship: location_of CCO:B0063165 ! RPB11_HUMAN relationship: location_of CCO:B0063166 ! RPB7_HUMAN relationship: location_of CCO:B0063167 ! RPAB1_HUMAN relationship: location_of CCO:B0063168 ! RPB2_HUMAN relationship: location_of CCO:B0063175 ! DIMT1_HUMAN relationship: location_of CCO:B0063194 ! MOFA1_HUMAN relationship: location_of CCO:B0063200 ! SH3L2_HUMAN relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0063207 ! CYTB_HUMAN relationship: location_of CCO:B0063233 ! BCA3_HUMAN relationship: location_of CCO:B0063234 ! MGN_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0063245 ! GCKR_HUMAN relationship: location_of CCO:B0063270 ! DZIP1_HUMAN relationship: location_of CCO:B0063274 ! SMYD3_HUMAN relationship: location_of CCO:B0063276 ! CS029_HUMAN relationship: location_of CCO:B0063286 ! LEG3_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063316 ! R3HD2_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0063344 ! CSTF2_HUMAN relationship: location_of CCO:B0063345 ! PEBB_HUMAN relationship: location_of CCO:B0063350 ! TRI11_HUMAN relationship: location_of CCO:B0063380 ! PDIP2_HUMAN relationship: location_of CCO:B0063382 ! HNRPR_HUMAN relationship: location_of CCO:B0063386 ! NP1L5_HUMAN relationship: location_of CCO:B0063391 ! UBE2B_HUMAN relationship: location_of CCO:B0063415 ! GEMI7_HUMAN relationship: location_of CCO:B0063419 ! PGAM5_HUMAN relationship: location_of CCO:B0063425 ! THOC7_HUMAN relationship: location_of CCO:B0063434 ! KLDC2_HUMAN relationship: location_of CCO:B0063445 ! BLMH_HUMAN relationship: location_of CCO:B0063446 ! CK001_HUMAN relationship: location_of CCO:B0063465 ! CD027_HUMAN relationship: location_of CCO:B0063525 ! NOVA1_HUMAN relationship: location_of CCO:B0063544 ! ARHG8_HUMAN-Phosphoserine106 relationship: location_of CCO:B0063573 ! ARI1B_HUMAN-Phosphoserine1559 relationship: location_of CCO:B0063575 ! ARI3A_HUMAN-Phosphoserine81 relationship: location_of CCO:B0063588 ! ARI4B_HUMAN-Phosphoserine1159 relationship: location_of CCO:B0063628 ! ASH1L_HUMAN-Phosphoserine22 relationship: location_of CCO:B0063632 ! ASPP2_HUMAN-Phosphoserine569 relationship: location_of CCO:B0063633 ! ASXL1_HUMAN-Phosphoserine503 relationship: location_of CCO:B0063634 ! ASXL2_HUMAN-Phosphoserine137 relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: location_of CCO:B0063652 ! ATF2_HUMAN-Phosphothreonine71 relationship: location_of CCO:B0063661 ! ATX1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0063688 ! AXN2_HUMAN-Phosphothreonine640 relationship: location_of CCO:B0063691 ! BACH1_HUMAN-Phosphoserine445 relationship: location_of CCO:B0063748 ! BAZ1A_HUMAN-Phosphoserine1371 relationship: location_of CCO:B0063758 ! BAZ1B_HUMAN-Phosphoserine347 relationship: location_of CCO:B0063772 ! BAZ2A_HUMAN-Phosphothreonine521 relationship: location_of CCO:B0063780 ! BAZ2B_HUMAN-Phosphothreonine1087 relationship: location_of CCO:B0063783 ! BBX_HUMAN-Phosphothreonine809 relationship: location_of CCO:B0063800 ! BCL9L_HUMAN-Phosphoserine118 relationship: location_of CCO:B0063820 ! BCLF1_HUMAN-Phosphoserine177 relationship: location_of CCO:B0063866 ! BCOR_HUMAN-Phosphoserine423 relationship: location_of CCO:B0063942 ! BMI1_HUMAN-Phosphoserine251 relationship: location_of CCO:B0063945 ! BNC1_HUMAN-Phosphoserine537 relationship: location_of CCO:B0063979 ! BPTF_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0063986 ! BRD8_HUMAN-Phosphoserine637 relationship: location_of CCO:B0063992 ! BRWD1_HUMAN-Phosphoserine696 relationship: location_of CCO:B0064008 ! BT3L3_HUMAN-Phosphoserine77 relationship: location_of CCO:B0064010 ! BTB14_HUMAN-Phosphoserine259 relationship: location_of CCO:B0064015 ! BTK_HUMAN-Phosphotyrosine344 relationship: location_of CCO:B0064020 ! C2D1A_HUMAN-Phosphoserine208 relationship: location_of CCO:B0064039 ! CABYR_HUMAN-Phosphoserine362 relationship: location_of CCO:B0064046 ! CACO1_HUMAN-Phosphoserine563 relationship: location_of CCO:B0064093 ! CBLC_HUMAN-Phosphoserine40 relationship: location_of CCO:B0064094 ! CBP_HUMAN-Phosphoserine121 relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 relationship: location_of CCO:B0064102 ! CBX4_HUMAN-Phosphothreonine495 relationship: location_of CCO:B0064104 ! CBX6_HUMAN-Phosphoserine303 relationship: location_of CCO:B0064109 ! CBX8_HUMAN-Phosphoserine332 relationship: location_of CCO:B0064178 ! CDA7L_HUMAN-Phosphoserine21 relationship: location_of CCO:B0064224 ! CDCA5_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0064236 ! CDN1C_HUMAN-Phosphoserine268 relationship: location_of CCO:B0064268 ! CENG1_HUMAN-Phosphoserine865 relationship: location_of CCO:B0064292 ! CENPU_HUMAN-Phosphoserine111 relationship: location_of CCO:B0064318 ! CHD4_HUMAN-Phosphothreonine1542 relationship: location_of CCO:B0064325 ! CHD6_HUMAN-Phosphoserine1069 relationship: location_of CCO:B0064338 ! CHD8_HUMAN-Phosphoserine1716 relationship: location_of CCO:B0064344 ! CHD9_HUMAN-Phosphoserine616 relationship: location_of CCO:B0064360 ! CIR_HUMAN-Phosphoserine202 relationship: location_of CCO:B0064392 ! CLSPN_HUMAN-Phosphoserine83 relationship: location_of CCO:B0064402 ! CMTA1_HUMAN-Phosphotyrosine117 relationship: location_of CCO:B0064407 ! CN043_HUMAN-Phosphothreonine715 relationship: location_of CCO:B0064409 ! CND2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0064461 ! CR3L3_HUMAN-Phosphoserine256 relationship: location_of CCO:B0064465 ! CREM_HUMAN-Phosphoserine277 relationship: location_of CCO:B0064473 ! CRK_HUMAN-Phosphoserine41 relationship: location_of CCO:B0064481 ! CRTC1_HUMAN-Phosphoserine139 relationship: location_of CCO:B0064491 ! CRTC2_HUMAN-Phosphoserine90 relationship: location_of CCO:B0064508 ! CRTC3_HUMAN-Phosphoserine129 relationship: location_of CCO:B0064567 ! CTBP1_HUMAN-Phosphoserine300 relationship: location_of CCO:B0064569 ! CTBP2_HUMAN-Phosphoserine428 relationship: location_of CCO:B0064579 ! CTND2_HUMAN-Phosphoserine415 relationship: location_of CCO:B0064605 ! CXXC1_HUMAN-Phosphoserine224 relationship: location_of CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0064683 ! DD19B_HUMAN-Phosphoserine86 relationship: location_of CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: location_of CCO:B0064744 ! DFFA_HUMAN-Phosphoserine315 relationship: location_of CCO:B0064748 ! DGCR8_HUMAN-Phosphoserine271 relationship: location_of CCO:B0064753 ! DGKI_HUMAN-Phosphotyrosine1053 relationship: location_of CCO:B0064786 ! DLX2_HUMAN-Phosphoserine232 relationship: location_of CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: location_of CCO:B0064803 ! DNLI1_HUMAN-Phosphoserine66 relationship: location_of CCO:B0064811 ! DNLI3_HUMAN-Phosphothreonine122 relationship: location_of CCO:B0064815 ! DNLI4_HUMAN-Phosphothreonine347 relationship: location_of CCO:B0064856 ! DPOLL_HUMAN-Phosphoserine246 relationship: location_of CCO:B0064857 ! DPOLM_HUMAN-Phosphoserine12 relationship: location_of CCO:B0064860 ! DPOLZ_HUMAN-Phosphothreonine2298 relationship: location_of CCO:B0064882 ! DSN1_HUMAN-Phosphoserine81 relationship: location_of CCO:B0064885 ! DSRAD_HUMAN-Phosphothreonine808 relationship: location_of CCO:B0064890 ! DTBP1_HUMAN-Phosphoserine321 relationship: location_of CCO:B0064897 ! DTL_HUMAN-Phosphoserine676 relationship: location_of CCO:B0064904 ! DUS10_HUMAN-Phosphoserine4 relationship: location_of CCO:B0064938 ! EI2BE_HUMAN-Phosphoserine525 relationship: location_of CCO:B0064954 ! EIF3A_HUMAN-Phosphoserine584 relationship: location_of CCO:B0064972 ! ELAV1_HUMAN-arginine217 relationship: location_of CCO:B0064975 ! ELF2_HUMAN-Phosphoserine191 relationship: location_of CCO:B0064979 ! ELF4_HUMAN-Phosphothreonine643 relationship: location_of CCO:B0065041 ! ELOA1_HUMAN-Phosphoserine125 relationship: location_of CCO:B0065043 ! ELP3_HUMAN-Phosphotyrosine202 relationship: location_of CCO:B0065045 ! ELP4_HUMAN-Phosphoserine42 relationship: location_of CCO:B0065064 ! EMSY_HUMAN-Phosphothreonine274 relationship: location_of CCO:B0065071 ! ENL_HUMAN-Phosphoserine361 relationship: location_of CCO:B0065131 ! ERF_HUMAN-Phosphothreonine441 relationship: location_of CCO:B0065134 ! ERG_HUMAN-Phosphoserine93 relationship: location_of CCO:B0065137 ! ERR1_HUMAN-Phosphoserine27 relationship: location_of CCO:B0065138 ! ESCO1_HUMAN-Phosphoserine200 relationship: location_of CCO:B0065152 ! ESF1_HUMAN-Phosphothreonine311 relationship: location_of CCO:B0065163 ! ESR2_HUMAN-Phosphoserine87 relationship: location_of CCO:B0065185 ! EYA3_HUMAN-Phosphoserine266 relationship: location_of CCO:B0065196 ! 2A5D_HUMAN-Phosphoserine573 relationship: location_of CCO:B0065233 ! AAKB1_HUMAN-Phosphoserine6 relationship: location_of CCO:B0065258 ! AAPK2_HUMAN-Phosphoserine173 relationship: location_of CCO:B0065340 ! ACINU_HUMAN-Phosphothreonine414 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0065454 ! AEBP2_HUMAN-Phosphoserine27 relationship: location_of CCO:B0065461 ! AF9_HUMAN-Phosphoserine412 relationship: location_of CCO:B0065486 ! AFF4_HUMAN-Phosphoserine1058 relationship: location_of CCO:B0065565 ! AKP13_HUMAN-Phosphoserine1929 relationship: location_of CCO:B0065574 ! AKP8L_HUMAN-Phosphoserine297 relationship: location_of CCO:B0065642 ! ANR17_HUMAN-Phosphoserine2042 relationship: location_of CCO:B0065664 ! AP2C_HUMAN-Phosphoserine434 relationship: location_of CCO:B0065751 ! ARIP4_HUMAN-Phosphoserine1172 relationship: location_of CCO:B0065796 ! BCORL_HUMAN-Phosphoserine1033 relationship: location_of CCO:B0065820 ! CASC3_HUMAN-Phosphoserine363 relationship: location_of CCO:B0065850 ! CE350_HUMAN-Phosphoserine1259 relationship: location_of CCO:B0065891 ! CPSF5_HUMAN-Phosphotyrosine40 relationship: location_of CCO:B0065893 ! CPSF6_HUMAN-Phosphothreonine404 relationship: location_of CCO:B0065932 ! DDX21_HUMAN-Phosphoserine168 relationship: location_of CCO:B0065937 ! DDX23_HUMAN-Phosphoserine107 relationship: location_of CCO:B0065940 ! DDX50_HUMAN-Phosphoserine82 relationship: location_of CCO:B0065942 ! DDX52_HUMAN-Phosphoserine99 relationship: location_of CCO:B0066003 ! EMD_HUMAN-Phosphotyrosine105 relationship: location_of CCO:B0066010 ! EPN1_HUMAN-Phosphoserine395 relationship: location_of CCO:B0066045 ! F10C1_HUMAN-Phosphoserine283 relationship: location_of CCO:B0066115 ! FAF1_HUMAN-Phosphothreonine580 relationship: location_of CCO:B0066118 ! FANCE_HUMAN-Phosphoserine249 relationship: location_of CCO:B0066119 ! FANCJ_HUMAN-Phosphothreonine918 relationship: location_of CCO:B0066166 ! FER_HUMAN-Phosphoserine434 relationship: location_of CCO:B0066197 ! FIZ1_HUMAN-Phosphothreonine74 relationship: location_of CCO:B0066198 ! FKBP5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0066204 ! FLI1_HUMAN-Phosphoserine86 relationship: location_of CCO:B0066247 ! FOSL2_HUMAN-Phosphoserine120 relationship: location_of CCO:B0066252 ! FOXC1_HUMAN-Phosphoserine235 relationship: location_of CCO:B0066259 ! FOXJ3_HUMAN-Phosphoserine223 relationship: location_of CCO:B0066269 ! FOXM1_HUMAN-Phosphothreonine662 relationship: location_of CCO:B0066288 ! FUBP1_HUMAN-Phosphotyrosine58 relationship: location_of CCO:B0066292 ! FUBP2_HUMAN-Phosphothreonine100 relationship: location_of CCO:B0066315 ! FUSIP_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0066317 ! FUS_HUMAN-Omega-N-methylated arginine216 relationship: location_of CCO:B0066413 ! GCFC_HUMAN-Phosphoserine557 relationship: location_of CCO:B0066415 ! GCF_HUMAN-Phosphoserine16 relationship: location_of CCO:B0066429 ! GCR_HUMAN-Phosphoserine141 relationship: location_of CCO:B0066440 ! GEMI2_HUMAN-Phosphothreonine48 relationship: location_of CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 relationship: location_of CCO:B0066469 ! GLRX2_HUMAN-cysteine77 relationship: location_of CCO:B0066473 ! GMEB1_HUMAN-Phosphoserine129 relationship: location_of CCO:B0066505 ! GO45_HUMAN-Phosphoserine353 relationship: location_of CCO:B0066516 ! GON4L_HUMAN-Phosphoserine181 relationship: location_of CCO:B0066616 ! GRIPE_HUMAN-Phosphoserine860 relationship: location_of CCO:B0066646 ! GTF2I_HUMAN-Phosphotyrosine248 relationship: location_of CCO:B0066678 ! H12_HUMAN-Phosphoserine173 relationship: location_of CCO:B0066679 ! H1X_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066682 ! H2A1C_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066694 ! H2AY_HUMAN-N6-methyllysine18 relationship: location_of CCO:B0066708 ! H2B1B_HUMAN-N6-acetyllysine109 relationship: location_of CCO:B0066710 ! H2B1H_HUMAN-N6-acetyllysine6 relationship: location_of CCO:B0066732 ! H31T_HUMAN-Citrulline18 relationship: location_of CCO:B0066745 ! HABP4_HUMAN-Phosphoserine108 relationship: location_of CCO:B0066755 ! HASP_HUMAN-Phosphoserine147 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066765 ! HCC1_HUMAN-Phosphoserine163 relationship: location_of CCO:B0066767 ! HCFC1_HUMAN-Phosphoserine1205 relationship: location_of CCO:B0066784 ! HDGF_HUMAN-Phosphoserine199 relationship: location_of CCO:B0066799 ! HEXI2_HUMAN-Phosphothreonine32 relationship: location_of CCO:B0066804 ! HIPK2_HUMAN-Phosphotyrosine361 relationship: location_of CCO:B0066805 ! HIPK3_HUMAN-Phosphotyrosine359 relationship: location_of CCO:B0066806 ! HIRA_HUMAN-Phosphothreonine576 relationship: location_of CCO:B0066814 ! HLTF_HUMAN-Phosphotyrosine394 relationship: location_of CCO:B0066820 ! HM20A_HUMAN-Phosphoserine105 relationship: location_of CCO:B0066824 ! HMGA1_HUMAN-Phosphoserine36 relationship: location_of CCO:B0066832 ! HMGN2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0066845 ! HN1L_HUMAN-Phosphoserine97 relationship: location_of CCO:B0066851 ! HNF1B_HUMAN-Phosphoserine80 relationship: location_of CCO:B0066854 ! HNRH1_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0066856 ! HNRH2_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0066860 ! HNRL1_HUMAN-Phosphoserine512 relationship: location_of CCO:B0066865 ! HNRPG_HUMAN-Phosphoserine326 relationship: location_of CCO:B0066869 ! HNRPM_HUMAN-Phosphoserine432 relationship: location_of CCO:B0066887 ! HNRPU_HUMAN-Omega-N-methylated arginine732 relationship: location_of CCO:B0066890 ! HOMEZ_HUMAN-Phosphothreonine427 relationship: location_of CCO:B0066902 ! HRX_HUMAN-Phosphoserine680 relationship: location_of CCO:B0066921 ! HS74L_HUMAN-Phosphoserine74 relationship: location_of CCO:B0066938 ! HTF4_HUMAN-Phosphoserine305 relationship: location_of CCO:B0066945 ! HTSF1_HUMAN-Phosphoserine557 relationship: location_of CCO:B0066962 ! HXB2_HUMAN-Phosphothreonine52 relationship: location_of CCO:B0066965 ! HXD11_HUMAN-Phosphoserine203 relationship: location_of CCO:B0066972 ! I2BP1_HUMAN-Phosphoserine436 relationship: location_of CCO:B0066978 ! I2BP2_HUMAN-Phosphoserine460 relationship: location_of CCO:B0066983 ! IASPP_HUMAN-Phosphoserine119 relationship: location_of CCO:B0067002 ! ICLN_HUMAN-Phosphoserine102 relationship: location_of CCO:B0067057 ! IF6_HUMAN-Phosphoserine243 relationship: location_of CCO:B0067059 ! IFIH1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0067061 ! IFRD1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0067069 ! IKBP1_HUMAN-Phosphoserine242 relationship: location_of CCO:B0067119 ! INO80_HUMAN-Phosphothreonine1550 relationship: location_of CCO:B0067121 ! IPO9_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0067140 ! IQEC1_HUMAN-Phosphoserine515 relationship: location_of CCO:B0067155 ! ISL1_HUMAN-Phosphothreonine182 relationship: location_of CCO:B0067157 ! ISL2_HUMAN-Phosphoserine157 relationship: location_of CCO:B0067179 ! JAD1A_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0067186 ! JAD1C_HUMAN-Phosphoserine317 relationship: location_of CCO:B0067190 ! JADE1_HUMAN-Phosphoserine10 relationship: location_of CCO:B0067209 ! JHD2C_HUMAN-Phosphoserine373 relationship: location_of CCO:B0067215 ! JHD3A_HUMAN-Phosphotyrosine547 relationship: location_of CCO:B0067216 ! JHD3B_HUMAN-Phosphothreonine305 relationship: location_of CCO:B0067219 ! JIP1_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0067230 ! JUND_HUMAN-Phosphoserine255 relationship: location_of CCO:B0067235 ! K1267_HUMAN-Phosphoserine249 relationship: location_of CCO:B0067238 ! K1688_HUMAN-Phosphoserine406 relationship: location_of CCO:B0067243 ! K2018_HUMAN-Phosphoserine1775 relationship: location_of CCO:B0067250 ! KAISO_HUMAN-Phosphotyrosine442 relationship: location_of CCO:B0067316 ! KI67_HUMAN-Phosphoserine1256 relationship: location_of CCO:B0067359 ! KIF22_HUMAN-Phosphoserine412 relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: location_of CCO:B0067372 ! KLF10_HUMAN-Phosphoserine249 relationship: location_of CCO:B0067381 ! KLF3_HUMAN-Phosphoserine92 relationship: location_of CCO:B0067418 ! KPCD_HUMAN-Phosphoserine307 relationship: location_of CCO:B0067447 ! KRR1_HUMAN-Phosphothreonine337 relationship: location_of CCO:B0067458 ! KS6A2_HUMAN-Phosphoserine218 relationship: location_of CCO:B0067479 ! KS6A5_HUMAN-Phosphoserine752 relationship: location_of CCO:B0067520 ! LAP2A_HUMAN-Phosphoserine66 relationship: location_of CCO:B0067579 ! LATS2_HUMAN-Phosphoserine380 relationship: location_of CCO:B0067595 ! LBH_HUMAN-Phosphoserine63 relationship: location_of CCO:B0067600 ! LCOR_HUMAN-Phosphoserine367 relationship: location_of CCO:B0067625 ! LEO1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0067676 ! LIN9_HUMAN-Phosphothreonine304 relationship: location_of CCO:B0067683 ! LMBL2_HUMAN-Phosphoserine12 relationship: location_of CCO:B0067690 ! LMBL3_HUMAN-Phosphoserine608 relationship: location_of CCO:B0067706 ! LMNA_HUMAN-Phosphothreonine416 relationship: location_of CCO:B0067727 ! LMNB1_HUMAN-Phosphothreonine575 relationship: location_of CCO:B0067737 ! LMO7_HUMAN-Phosphoserine867 relationship: location_of CCO:B0067781 ! LRRF1_HUMAN-Phosphoserine581 relationship: location_of CCO:B0067787 ! LSM2_HUMAN-Phosphothreonine79 relationship: location_of CCO:B0067798 ! LYAR_HUMAN-Phosphoserine258 relationship: location_of CCO:B0067817 ! M3K2_HUMAN-Phosphoserine331 relationship: location_of CCO:B0067850 ! MAGG1_HUMAN-Phosphoserine57 relationship: location_of CCO:B0067985 ! MAPK2_HUMAN-Phosphoserine328 relationship: location_of CCO:B0068027 ! MBB1A_HUMAN-Phosphothreonine1190 relationship: location_of CCO:B0068042 ! MBD2_HUMAN-Phosphoserine407 relationship: location_of CCO:B0068043 ! MBIP1_HUMAN-Phosphoserine91 relationship: location_of CCO:B0068044 ! MCA3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068050 ! MCAF1_HUMAN-Phosphoserine673 relationship: location_of CCO:B0068058 ! MCL1_HUMAN-Phosphothreonine163 relationship: location_of CCO:B0068112 ! MECP2_HUMAN-Phosphoserine80 relationship: location_of CCO:B0068121 ! MED13_HUMAN-Phosphoserine537 relationship: location_of CCO:B0068135 ! MEF2A_HUMAN-Phosphoserine408 relationship: location_of CCO:B0068137 ! MEF2C_HUMAN-Phosphoserine396 relationship: location_of CCO:B0068157 ! MGAP_HUMAN-Phosphoserine1457 relationship: location_of CCO:B0068161 ! MGMT_HUMAN-Phosphoserine201 relationship: location_of CCO:B0068177 ! MIER1_HUMAN-Phosphoserine190 relationship: location_of CCO:B0068185 ! MIER3_HUMAN-Phosphoserine168 relationship: location_of CCO:B0068191 ! MINT_HUMAN-Phosphoserine1390 relationship: location_of CCO:B0068205 ! MIXL1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0068213 ! MKL1_HUMAN-Phosphothreonine450 relationship: location_of CCO:B0068215 ! MKL2_HUMAN-Phosphoserine66 relationship: location_of CCO:B0068219 ! MKNK1_HUMAN-Phosphothreonine250 relationship: location_of CCO:B0068226 ! MLH1_HUMAN-Phosphoserine477 relationship: location_of CCO:B0068239 ! MLXIP_HUMAN-Phosphoserine27 relationship: location_of CCO:B0068242 ! MLX_HUMAN-Phosphoserine48 relationship: location_of CCO:B0068243 ! MMS19_HUMAN-Phosphoserine371 relationship: location_of CCO:B0068247 ! MNX1_HUMAN-Phosphoserine79 relationship: location_of CCO:B0068248 ! MO4L2_HUMAN-Phosphoserine71 relationship: location_of CCO:B0068256 ! MPIP3_HUMAN-Phosphoserine57 relationship: location_of CCO:B0068286 ! MRE11_HUMAN-Phosphoserine649 relationship: location_of CCO:B0068287 ! MRGBP_HUMAN-Phosphoserine191 relationship: location_of CCO:B0068295 ! MS3L1_HUMAN-Phosphoserine411 relationship: location_of CCO:B0068306 ! MTA1_HUMAN-Phosphoserine386 relationship: location_of CCO:B0068312 ! MTA2_HUMAN-Phosphoserine57 relationship: location_of CCO:B0068317 ! MTG8R_HUMAN-Phosphoserine33 relationship: location_of CCO:B0068359 ! MYCB2_HUMAN-Phosphoserine3894 relationship: location_of CCO:B0068361 ! MYCL1_HUMAN-Phosphoserine313 relationship: location_of CCO:B0068363 ! MYCN_HUMAN-Phosphothreonine58 relationship: location_of CCO:B0068367 ! MYCPP_HUMAN-Phosphoserine728 relationship: location_of CCO:B0068421 ! MYSM1_HUMAN-Phosphoserine234 relationship: location_of CCO:B0068424 ! MYST1_HUMAN-Phosphoserine42 relationship: location_of CCO:B0068428 ! NAB1_HUMAN-Phosphoserine328 relationship: location_of CCO:B0068434 ! NAB2_HUMAN-Phosphoserine479 relationship: location_of CCO:B0068440 ! NARG1_HUMAN-Phosphoserine855 relationship: location_of CCO:B0068446 ! NAT10_HUMAN-Phosphoserine987 relationship: location_of CCO:B0068448 ! NC2B_HUMAN-Phosphoserine105 relationship: location_of CCO:B0068452 ! NCBP1_HUMAN-Phosphoserine22 relationship: location_of CCO:B0068468 ! NCOA1_HUMAN-Phosphoserine372 relationship: location_of CCO:B0068476 ! NCOA2_HUMAN-Phosphoserine699 relationship: location_of CCO:B0068486 ! NCOA5_HUMAN-Phosphoserine387 relationship: location_of CCO:B0068498 ! NCOR1_HUMAN-Phosphoserine999 relationship: location_of CCO:B0068518 ! NCOR2_HUMAN-Phosphothreonine2065 relationship: location_of CCO:B0068532 ! NDRG1_HUMAN-Phosphoserine330 relationship: location_of CCO:B0068563 ! NELFA_HUMAN-Phosphoserine233 relationship: location_of CCO:B0068569 ! NELFE_HUMAN-Phosphoserine131 relationship: location_of CCO:B0068597 ! NF2IP_HUMAN-Phosphoserine204 relationship: location_of CCO:B0068603 ! NFAC1_HUMAN-Phosphoserine117 relationship: location_of CCO:B0068629 ! NFAC2_HUMAN-Phosphoserine605 relationship: location_of CCO:B0068630 ! NFAC4_HUMAN-Phosphoserine272 relationship: location_of CCO:B0068635 ! NFIA_HUMAN-Phosphoserine258 relationship: location_of CCO:B0068644 ! NFIB_HUMAN-Phosphoserine292 relationship: location_of CCO:B0068653 ! NFIC_HUMAN-Phosphoserine339 relationship: location_of CCO:B0068657 ! NFIL3_HUMAN-Phosphoserine301 relationship: location_of CCO:B0068667 ! NFKB1_HUMAN-Phosphoserine907 relationship: location_of CCO:B0068691 ! NFX1_HUMAN-Phosphoserine49 relationship: location_of CCO:B0068697 ! NFXL1_HUMAN-Phosphoserine107 relationship: location_of CCO:B0068715 ! NHRF2_HUMAN-Phosphoserine183 relationship: location_of CCO:B0068738 ! NLK_HUMAN-Phosphothreonine286 relationship: location_of CCO:B0068757 ! NO66_HUMAN-Phosphoserine109 relationship: location_of CCO:B0068778 ! NOL8_HUMAN-Phosphoserine845 relationship: location_of CCO:B0068819 ! NR2C2_HUMAN-Phosphothreonine224 relationship: location_of CCO:B0068820 ! NR2E1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0068824 ! NR4A2_HUMAN-Phosphoserine181 relationship: location_of CCO:B0068837 ! NRIP1_HUMAN-Phosphoserine104 relationship: location_of CCO:B0068858 ! NSBP1_HUMAN-Phosphoserine24 relationship: location_of CCO:B0068862 ! NSD1_HUMAN-Phosphoserine2471 relationship: location_of CCO:B0068863 ! NSD2_HUMAN-Phosphoserine102 relationship: location_of CCO:B0068866 ! NSF1C_HUMAN-Phosphoserine114 relationship: location_of CCO:B0068898 ! NU107_HUMAN-Phosphothreonine64 relationship: location_of CCO:B0068907 ! NU133_HUMAN-Phosphoserine501 relationship: location_of CCO:B0068941 ! NUP98_HUMAN-Phosphoserine1060 relationship: location_of CCO:B0068948 ! NUSAP_HUMAN-Phosphothreonine349 relationship: location_of CCO:B0068967 ! OGFR_HUMAN-Phosphoserine484 relationship: location_of CCO:B0068985 ! ORC1_HUMAN-Phosphothreonine337 relationship: location_of CCO:B0068990 ! ORC2_HUMAN-Phosphoserine280 relationship: location_of CCO:B0069006 ! OTU7B_HUMAN-Phosphoserine449 relationship: location_of CCO:B0069051 ! PAF1_HUMAN-Phosphoserine456 relationship: location_of CCO:B0069062 ! PAIRB_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0069065 ! PAK2_HUMAN-Phosphoserine58 relationship: location_of CCO:B0069092 ! PAPOA_HUMAN-Phosphoserine24 relationship: location_of CCO:B0069095 ! PAR12_HUMAN-Phosphoserine263 relationship: location_of CCO:B0069107 ! PARF_HUMAN-Phosphoserine471 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0069129 ! PAWR_HUMAN-Phosphothreonine229 relationship: location_of CCO:B0069142 ! PB1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0069148 ! PBIP1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0069149 ! PBX2_HUMAN-Phosphoserine330 relationship: location_of CCO:B0069153 ! PCNP_HUMAN-Phosphoserine87 relationship: location_of CCO:B0069190 ! PDS5B_HUMAN-Phosphoserine1283 relationship: location_of CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 relationship: location_of CCO:B0069215 ! PER1_HUMAN-Phosphoserine1100 relationship: location_of CCO:B0069232 ! PER2_HUMAN-Phosphoserine977 relationship: location_of CCO:B0069234 ! PERM_HUMAN-Cysteine sulfenic acid (-SOH)316 relationship: location_of CCO:B0069236 ! PESC_HUMAN-Phosphotyrosine548 relationship: location_of CCO:B0069237 ! PEX14_HUMAN-Phosphoserine335 relationship: location_of CCO:B0069239 ! PGBD1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0069245 ! PHB2_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0069250 ! PHF10_HUMAN-Phosphoserine213 relationship: location_of CCO:B0069253 ! PHF12_HUMAN-Phosphothreonine671 relationship: location_of CCO:B0069257 ! PHF6_HUMAN-Phosphoserine120 relationship: location_of CCO:B0069308 ! PIF1_HUMAN-Phosphoserine151 relationship: location_of CCO:B0069315 ! PITX1_HUMAN-Phosphoserine50 relationship: location_of CCO:B0069318 ! PK1IP_HUMAN-Phosphoserine320 relationship: location_of CCO:B0069380 ! PKP2_HUMAN-Phosphoserine329 relationship: location_of CCO:B0069430 ! PNKP_HUMAN-Phosphoserine114 relationship: location_of CCO:B0069451 ! PP1G_HUMAN-Phosphothreonine307 relationship: location_of CCO:B0069454 ! PP1R8_HUMAN-Phosphotyrosine264 relationship: location_of CCO:B0069474 ! PR38A_HUMAN-Phosphoserine279 relationship: location_of CCO:B0069483 ! PR40A_HUMAN-Phosphoserine933 relationship: location_of CCO:B0069487 ! PRD10_HUMAN-Phosphoserine338 relationship: location_of CCO:B0069491 ! PRDM2_HUMAN-Phosphoserine643 relationship: location_of CCO:B0069499 ! PRGC2_HUMAN-Phosphoserine524 relationship: location_of CCO:B0069503 ! PRGR_HUMAN-Phosphoserine102 relationship: location_of CCO:B0069525 ! PRKDC_HUMAN-Phosphoserine4026 relationship: location_of CCO:B0069547 ! PRP19_HUMAN-Phosphothreonine342 relationship: location_of CCO:B0069558 ! PRPF3_HUMAN-Phosphoserine619 relationship: location_of CCO:B0069559 ! PRRX1_HUMAN-Phosphoserine197 relationship: location_of CCO:B0069574 ! PSIP1_HUMAN-Phosphoserine177 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069621 ! PUF60_HUMAN-Phosphothreonine60 relationship: location_of CCO:B0069637 ! PURA_HUMAN-Phosphoserine8 relationship: location_of CCO:B0069644 ! PWP2_HUMAN-Phosphoserine902 relationship: location_of CCO:B0069716 ! RAI1_HUMAN-Phosphoserine1431 relationship: location_of CCO:B0069728 ! RANB3_HUMAN-Phosphoserine355 relationship: location_of CCO:B0069732 ! RANG_HUMAN-Phosphothreonine7 relationship: location_of CCO:B0069768 ! RBBP7_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069784 ! RBM14_HUMAN-Phosphothreonine572 relationship: location_of CCO:B0069801 ! RBM15_HUMAN-Phosphoserine622 relationship: location_of CCO:B0069815 ! RBM39_HUMAN-Phosphoserine127 relationship: location_of CCO:B0069843 ! RCOR1_HUMAN-Phosphoserine124 relationship: location_of CCO:B0069846 ! RCOR3_HUMAN-Phosphoserine156 relationship: location_of CCO:B0069848 ! RD23A_HUMAN-Phosphoserine128 relationship: location_of CCO:B0069877 ! REQU_HUMAN-Phosphothreonine176 relationship: location_of CCO:B0069881 ! RERE_HUMAN-Phosphoserine56 relationship: location_of CCO:B0069902 ! RFX7_HUMAN-Phosphoserine1081 relationship: location_of CCO:B0069906 ! RGAP1_HUMAN-Phosphoserine600 relationship: location_of CCO:B0069955 ! RHG19_HUMAN-Phosphoserine422 relationship: location_of CCO:B0070039 ! RIF1_HUMAN-Phosphoserine2176 relationship: location_of CCO:B0070068 ! RL1D1_HUMAN-Phosphothreonine358 relationship: location_of CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 relationship: location_of CCO:B0070091 ! RLF_HUMAN-Phosphoserine41 relationship: location_of CCO:B0070094 ! RMI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0070096 ! RMP_HUMAN-Phosphothreonine242 relationship: location_of CCO:B0070107 ! RNF14_HUMAN-Phosphoserine348 relationship: location_of CCO:B0070116 ! RNPS1_HUMAN-Phosphoserine287 relationship: location_of CCO:B0070118 ! RNZ2_HUMAN-Phosphoserine199 relationship: location_of CCO:B0070146 ! RPA34_HUMAN-Phosphotyrosine80 relationship: location_of CCO:B0070149 ! RPA49_HUMAN-Phosphoserine225 relationship: location_of CCO:B0070150 ! RPAB2_HUMAN-Phosphoserine2 relationship: location_of CCO:B0070158 ! RPB9_HUMAN-Phosphoserine73 relationship: location_of CCO:B0070159 ! RPC3_HUMAN-Phosphoserine194 relationship: location_of CCO:B0070190 ! RREB1_HUMAN-Phosphothreonine1315 relationship: location_of CCO:B0070193 ! RRN3_HUMAN-Phosphoserine44 relationship: location_of CCO:B0070197 ! RRP5_HUMAN-Phosphoserine1360 relationship: location_of CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 relationship: location_of CCO:B0070245 ! RSF1_HUMAN-Phosphoserine1349 relationship: location_of CCO:B0070262 ! RU17_HUMAN-Phosphotyrosine126 relationship: location_of CCO:B0070268 ! RU2A_HUMAN-Phosphoserine197 relationship: location_of CCO:B0070270 ! RYBP_HUMAN-Phosphoserine130 relationship: location_of CCO:B0070274 ! S10AB_HUMAN-Phosphothreonine10 relationship: location_of CCO:B0070280 ! S30BP_HUMAN-Phosphoserine22 relationship: location_of CCO:B0070290 ! SAE2_HUMAN-Phosphoserine592 relationship: location_of CCO:B0070296 ! SAFB1_HUMAN-Phosphoserine384 relationship: location_of CCO:B0070308 ! SAFB2_HUMAN-Phosphoserine331 relationship: location_of CCO:B0070312 ! SALL1_HUMAN-Phosphoserine586 relationship: location_of CCO:B0070314 ! SALL2_HUMAN-Phosphothreonine616 relationship: location_of CCO:B0070317 ! SAP30_HUMAN-Phosphoserine138 relationship: location_of CCO:B0070323 ! SATB2_HUMAN-Phosphoserine446 relationship: location_of CCO:B0070348 ! SCMH1_HUMAN-Phosphoserine649 relationship: location_of CCO:B0070349 ! SCML1_HUMAN-Phosphoserine17 relationship: location_of CCO:B0070361 ! SCML2_HUMAN-Phosphoserine583 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070371 ! SEP10_HUMAN-Phosphoserine451 relationship: location_of CCO:B0070383 ! SETD2_HUMAN-Phosphothreonine1872 relationship: location_of CCO:B0070386 ! SETD8_HUMAN-Phosphoserine100 relationship: location_of CCO:B0070388 ! SF01_HUMAN-Phosphoserine20 relationship: location_of CCO:B0070394 ! SF17A_HUMAN-Phosphoserine633 relationship: location_of CCO:B0070396 ! SF3B4_HUMAN-Phosphotyrosine56 relationship: location_of CCO:B0070401 ! SFR14_HUMAN-Phosphoserine315 relationship: location_of CCO:B0070409 ! SFR16_HUMAN-Phosphoserine516 relationship: location_of CCO:B0070418 ! SFRS2_HUMAN-Phosphotyrosine23 relationship: location_of CCO:B0070432 ! SFRS5_HUMAN-Phosphoserine231 relationship: location_of CCO:B0070439 ! SFRS8_HUMAN-Phosphoserine834 relationship: location_of CCO:B0070537 ! SIN3A_HUMAN-Phosphoserine940 relationship: location_of CCO:B0070543 ! SIRT1_HUMAN-Phosphoserine47 relationship: location_of CCO:B0070548 ! SIRT6_HUMAN-Phosphothreonine294 relationship: location_of CCO:B0070563 ! SIVA_HUMAN-Phosphotyrosine34 relationship: location_of CCO:B0070565 ! SKAP1_HUMAN-Phosphotyrosine142 relationship: location_of CCO:B0070578 ! SLIRP_HUMAN-Phosphoserine102 relationship: location_of CCO:B0070580 ! SLTM_HUMAN-Phosphoserine97 relationship: location_of CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0070598 ! SMAD2_HUMAN-Phosphoserine255 relationship: location_of CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 relationship: location_of CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 relationship: location_of CCO:B0070613 ! SMBP2_HUMAN-Phosphoserine656 relationship: location_of CCO:B0070614 ! SMBT1_HUMAN-Phosphoserine765 relationship: location_of CCO:B0070619 ! SMCA1_HUMAN-Phosphotyrosine954 relationship: location_of CCO:B0070623 ! SMCA2_HUMAN-Phosphoserine1377 relationship: location_of CCO:B0070630 ! SMCA4_HUMAN-Phosphoserine613 relationship: location_of CCO:B0070643 ! SMCA5_HUMAN-Phosphoserine755 relationship: location_of CCO:B0070644 ! SMD2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070645 ! SMG7_HUMAN-Phosphoserine781 relationship: location_of CCO:B0070647 ! SMN_HUMAN-Phosphothreonine25 relationship: location_of CCO:B0070650 ! SMRCD_HUMAN-Phosphoserine34 relationship: location_of CCO:B0070680 ! SND1_HUMAN-Phosphothreonine429 relationship: location_of CCO:B0070691 ! SNPC1_HUMAN-Phosphoserine290 relationship: location_of CCO:B0070693 ! SNPC3_HUMAN-Phosphoserine74 relationship: location_of CCO:B0070694 ! SNPC4_HUMAN-Phosphothreonine1157 relationship: location_of CCO:B0070734 ! SON_HUMAN-Phosphoserine1784 relationship: location_of CCO:B0070751 ! SOX13_HUMAN-Phosphoserine368 relationship: location_of CCO:B0070752 ! SOX5_HUMAN-Phosphothreonine108 relationship: location_of CCO:B0070768 ! SP100_HUMAN-Phosphoserine459 relationship: location_of CCO:B0070772 ! SP130_HUMAN-Phosphoserine455 relationship: location_of CCO:B0070779 ! SP30L_HUMAN-Phosphoserine93 relationship: location_of CCO:B0070783 ! SP3_HUMAN-Phosphoserine566 relationship: location_of CCO:B0070794 ! SPEG_HUMAN-Phosphoserine476 relationship: location_of CCO:B0070797 ! SPF30_HUMAN-Phosphoserine201 relationship: location_of CCO:B0070801 ! SPN90_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0070813 ! SPT6H_HUMAN-Phosphoserine1535 relationship: location_of CCO:B0070846 ! SQSTM_HUMAN-Phosphoserine170 relationship: location_of CCO:B0070862 ! SRA1_HUMAN-Phosphothreonine68 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0070898 ! SRCAP_HUMAN-Phosphoserine248 relationship: location_of CCO:B0070912 ! SRGEF_HUMAN-Phosphoserine427 relationship: location_of CCO:B0070926 ! SRPK1_HUMAN-Phosphoserine309 relationship: location_of CCO:B0070931 ! SSBP3_HUMAN-Phosphoserine347 relationship: location_of CCO:B0070936 ! SSBP4_HUMAN-Phosphoserine342 relationship: location_of CCO:B0070944 ! ST17A_HUMAN-Phosphoserine28 relationship: location_of CCO:B0070946 ! STA5A_HUMAN-Phosphoserine193 relationship: location_of CCO:B0070950 ! STABP_HUMAN-Phosphoserine245 relationship: location_of CCO:B0070966 ! STAT3_HUMAN-Phosphothreonine714 relationship: location_of CCO:B0070967 ! STAT4_HUMAN-Phosphotyrosine693 relationship: location_of CCO:B0070971 ! STF1_HUMAN-N6-acetyllysine72 relationship: location_of CCO:B0070975 ! STK3_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0070996 ! SUFU_HUMAN-Phosphoserine481 relationship: location_of CCO:B0071003 ! SUV92_HUMAN-Phosphoserine381 relationship: location_of CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: location_of CCO:B0071024 ! SYCP1_HUMAN-Phosphotyrosine257 relationship: location_of CCO:B0071069 ! T22D4_HUMAN-Phosphoserine370 relationship: location_of CCO:B0071070 ! T2EA_HUMAN-Phosphoserine268 relationship: location_of CCO:B0071071 ! T2FB_HUMAN-Phosphoserine142 relationship: location_of CCO:B0071085 ! TAF12_HUMAN-Phosphothreonine43 relationship: location_of CCO:B0071087 ! TAF2_HUMAN-Phosphoserine1194 relationship: location_of CCO:B0071097 ! TAF3_HUMAN-Phosphoserine411 relationship: location_of CCO:B0071108 ! TAF7_HUMAN-Phosphoserine227 relationship: location_of CCO:B0071117 ! TAF9_HUMAN-Phosphoserine181 relationship: location_of CCO:B0071118 ! TAL1_HUMAN-Phosphoserine122 relationship: location_of CCO:B0071251 ! TCAL1_HUMAN-Phosphoserine48 relationship: location_of CCO:B0071255 ! TCAL4_HUMAN-Phosphoserine102 relationship: location_of CCO:B0071256 ! TCAL6_HUMAN-Phosphoserine125 relationship: location_of CCO:B0071262 ! TCEA1_HUMAN-Phosphothreonine108 relationship: location_of CCO:B0071283 ! TCF20_HUMAN-Phosphothreonine1671 relationship: location_of CCO:B0071284 ! TCF25_HUMAN-Phosphoserine602 relationship: location_of CCO:B0071304 ! TDIF2_HUMAN-Phosphoserine194 relationship: location_of CCO:B0071315 ! TEAD1_HUMAN-Phosphoserine9 relationship: location_of CCO:B0071340 ! TERF1_HUMAN-Phosphoserine435 relationship: location_of CCO:B0071342 ! TERT_HUMAN-Phosphothreonine1113 relationship: location_of CCO:B0071358 ! TF2AA_HUMAN-Phosphoserine281 relationship: location_of CCO:B0071361 ! TF2B_HUMAN-Phosphoserine76 relationship: location_of CCO:B0071362 ! TF2H5_HUMAN-Phosphothreonine69 relationship: location_of CCO:B0071368 ! TF3C1_HUMAN-Phosphoserine1632 relationship: location_of CCO:B0071370 ! TFAP4_HUMAN-Phosphoserine124 relationship: location_of CCO:B0071383 ! THOC1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0071407 ! TINF2_HUMAN-Phosphoserine295 relationship: location_of CCO:B0071416 ! TLE3_HUMAN-Phosphothreonine321 relationship: location_of CCO:B0071438 ! TNAP3_HUMAN-Phosphoserine575 relationship: location_of CCO:B0071456 ! TOX4_HUMAN-Phosphoserine182 relationship: location_of CCO:B0071518 ! TR150_HUMAN-Phosphoserine684 relationship: location_of CCO:B0071526 ! TRAF4_HUMAN-Phosphoserine426 relationship: location_of CCO:B0071531 ! TRBP2_HUMAN-Phosphoserine152 relationship: location_of CCO:B0071532 ! TREF1_HUMAN-Phosphoserine491 relationship: location_of CCO:B0071534 ! TREX1_HUMAN-Phosphoserine222 relationship: location_of CCO:B0071561 ! TRI41_HUMAN-Phosphoserine447 relationship: location_of CCO:B0071581 ! TRM61_HUMAN-Phosphoserine19 relationship: location_of CCO:B0071582 ! TRM6_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0071586 ! TRPS1_HUMAN-Phosphoserine127 relationship: location_of CCO:B0071591 ! TRXR1_HUMAN-Phosphotyrosine163 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: location_of CCO:B0071607 ! TSH3_HUMAN-Phosphoserine672 relationship: location_of CCO:B0071623 ! TTF2_HUMAN-Phosphoserine396 relationship: location_of CCO:B0071634 ! TXN4A_HUMAN-Phosphoserine132 relationship: location_of CCO:B0071635 ! TXN4B_HUMAN-Phosphoserine132 relationship: location_of CCO:B0071647 ! U2AF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0071653 ! U2AF2_HUMAN-Phosphoserine53 relationship: location_of CCO:B0071661 ! UACA_HUMAN-Phosphotyrosine723 relationship: location_of CCO:B0071663 ! UAP56_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0071667 ! UBF1_HUMAN-Phosphoserine484 relationship: location_of CCO:B0071674 ! UBN1_HUMAN-Phosphoserine493 relationship: location_of CCO:B0071675 ! UBP11_HUMAN-Phosphoserine905 relationship: location_of CCO:B0071718 ! UHRF2_HUMAN-Phosphoserine667 relationship: location_of CCO:B0071728 ! UIMC1_HUMAN-Phosphoserine677 relationship: location_of CCO:B0071752 ! USF2_HUMAN-Phosphothreonine293 relationship: location_of CCO:B0071767 ! UTP20_HUMAN-Phosphoserine788 relationship: location_of CCO:B0071797 ! VGLL4_HUMAN-Phosphoserine52 relationship: location_of CCO:B0071803 ! VINEX_HUMAN-Phosphothreonine529 relationship: location_of CCO:B0071833 ! WBS14_HUMAN-Phosphothreonine509 relationship: location_of CCO:B0071838 ! WDR3_HUMAN-Phosphotyrosine723 relationship: location_of CCO:B0071839 ! WDR74_HUMAN-Phosphoserine361 relationship: location_of CCO:B0071885 ! WWTR1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0071891 ! XPO7_HUMAN-Phosphotyrosine58 relationship: location_of CCO:B0071895 ! XRCC4_HUMAN-Phosphoserine327 relationship: location_of CCO:B0071902 ! YAF2_HUMAN-Phosphoserine167 relationship: location_of CCO:B0071928 ! YLPM1_HUMAN-Phosphoserine634 relationship: location_of CCO:B0071930 ! YYAP1_HUMAN-Phosphoserine724 relationship: location_of CCO:B0071931 ! Z280B_HUMAN-Phosphoserine105 relationship: location_of CCO:B0071936 ! Z280C_HUMAN-Phosphothreonine540 relationship: location_of CCO:B0071945 ! Z585A_HUMAN-Phosphoserine118 relationship: location_of CCO:B0071955 ! ZBT10_HUMAN-Phosphoserine565 relationship: location_of CCO:B0071958 ! ZBT12_HUMAN-Phosphothreonine19 relationship: location_of CCO:B0071969 ! ZBT40_HUMAN-Phosphothreonine412 relationship: location_of CCO:B0071975 ! ZBT44_HUMAN-Phosphoserine194 relationship: location_of CCO:B0071977 ! ZBT7A_HUMAN-Phosphoserine341 relationship: location_of CCO:B0071991 ! ZEB1_HUMAN-Phosphoserine679 relationship: location_of CCO:B0071994 ! ZEP1_HUMAN-Phosphoserine1874 relationship: location_of CCO:B0071996 ! ZEP2_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0072004 ! ZF106_HUMAN-Phosphoserine1026 relationship: location_of CCO:B0072012 ! ZFHX3_HUMAN-Phosphoserine1180 relationship: location_of CCO:B0072016 ! ZFHX4_HUMAN-Phosphoserine1892 relationship: location_of CCO:B0072021 ! ZFP91_HUMAN-Phosphothreonine395 relationship: location_of CCO:B0072035 ! ZHX3_HUMAN-Phosphoserine680 relationship: location_of CCO:B0072038 ! ZKSC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0072042 ! ZKSC2_HUMAN-Phosphoserine600 relationship: location_of CCO:B0072043 ! ZKSC4_HUMAN-Phosphoserine165 relationship: location_of CCO:B0072044 ! ZMYM2_HUMAN-Phosphoserine305 relationship: location_of CCO:B0072048 ! ZN101_HUMAN-Phosphoserine433 relationship: location_of CCO:B0072049 ! ZN142_HUMAN-Phosphoserine1319 relationship: location_of CCO:B0072053 ! ZN148_HUMAN-Phosphoserine306 relationship: location_of CCO:B0072056 ! ZN160_HUMAN-Phosphothreonine588 relationship: location_of CCO:B0072058 ! ZN174_HUMAN-Phosphotyrosine382 relationship: location_of CCO:B0072059 ! ZN180_HUMAN-Phosphoserine68 relationship: location_of CCO:B0072064 ! ZN217_HUMAN-Phosphoserine407 relationship: location_of CCO:B0072068 ! ZN219_HUMAN-Phosphoserine175 relationship: location_of CCO:B0072069 ! ZN224_HUMAN-Phosphoserine245 relationship: location_of CCO:B0072070 ! ZN225_HUMAN-Phosphothreonine283 relationship: location_of CCO:B0072071 ! ZN238_HUMAN-Phosphoserine516 relationship: location_of CCO:B0072073 ! ZN239_HUMAN-Phosphoserine41 relationship: location_of CCO:B0072078 ! ZN264_HUMAN-Phosphotyrosine483 relationship: location_of CCO:B0072083 ! ZN276_HUMAN-Phosphoserine93 relationship: location_of CCO:B0072087 ! ZN281_HUMAN-Phosphoserine484 relationship: location_of CCO:B0072103 ! ZN318_HUMAN-Phosphoserine1896 relationship: location_of CCO:B0072114 ! ZN335_HUMAN-Phosphoserine1153 relationship: location_of CCO:B0072119 ! ZN391_HUMAN-Phosphothreonine49 relationship: location_of CCO:B0072124 ! ZN423_HUMAN-Phosphoserine608 relationship: location_of CCO:B0072125 ! ZN432_HUMAN-Nitrated tyrosine41 relationship: location_of CCO:B0072127 ! ZN444_HUMAN-Phosphoserine235 relationship: location_of CCO:B0072137 ! ZN496_HUMAN-Phosphoserine185 relationship: location_of CCO:B0072146 ! ZN532_HUMAN-Phosphoserine268 relationship: location_of CCO:B0072165 ! ZN592_HUMAN-Phosphoserine146 relationship: location_of CCO:B0072177 ! ZN600_HUMAN-Phosphoserine116 relationship: location_of CCO:B0072182 ! ZN609_HUMAN-Phosphoserine846 relationship: location_of CCO:B0072185 ! ZN618_HUMAN-Phosphoserine16 relationship: location_of CCO:B0072196 ! ZN638_HUMAN-Phosphoserine605 relationship: location_of CCO:B0072201 ! ZN639_HUMAN-Phosphotyrosine4 relationship: location_of CCO:B0072204 ! ZN644_HUMAN-Phosphoserine1189 relationship: location_of CCO:B0072207 ! ZN652_HUMAN-Phosphoserine380 relationship: location_of CCO:B0072209 ! ZN654_HUMAN-Phosphoserine580 relationship: location_of CCO:B0072210 ! ZN665_HUMAN-Phosphotyrosine97 relationship: location_of CCO:B0072218 ! ZN687_HUMAN-Phosphothreonine900 relationship: location_of CCO:B0072227 ! ZN717_HUMAN-Phosphoserine391 relationship: location_of CCO:B0072233 ! ZN768_HUMAN-Phosphoserine18 relationship: location_of CCO:B0072239 ! ZN775_HUMAN-Phosphothreonine304 relationship: location_of CCO:B0072245 ! ZN787_HUMAN-Phosphoserine171 relationship: location_of CCO:B0072247 ! ZN800_HUMAN-Phosphoserine317 relationship: location_of CCO:B0072255 ! ZN846_HUMAN-Phosphoserine98 relationship: location_of CCO:B0072256 ! ZNF44_HUMAN-Phosphoserine427 relationship: location_of CCO:B0072258 ! ZNF8_HUMAN-Phosphoserine455 relationship: location_of CCO:B0072280 ! ZXDA_HUMAN-Phosphoserine34 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000253 name: nuclear envelope namespace: cellular_component def: "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684] subset: goslim_generic subset: goslim_plant xref: GO:0005635 xref: GO:0005636 is_a: CCO:C0001360 ! organelle envelope is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001494 ! S10A6_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0005409 ! IMB1_HUMAN relationship: location_of CCO:B0005467 ! PARP1_HUMAN relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 relationship: location_of CCO:B0012286 ! HTAI2_HUMAN-Phosphoserine45 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 relationship: location_of CCO:B0018951 ! ATF6A_HUMAN relationship: location_of CCO:B0021718 ! NUP62_HUMAN relationship: location_of CCO:B0030249 ! GNAZ_HUMAN relationship: location_of CCO:B0037229 ! PE2R3_HUMAN relationship: location_of CCO:B0043213 ! BNIP2_HUMAN-Phosphoserine114 relationship: location_of CCO:B0043374 ! RTN4_HUMAN-Phosphoserine863 relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0062780 ! NUP54_HUMAN relationship: location_of CCO:B0066003 ! EMD_HUMAN-Phosphotyrosine105 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0067520 ! LAP2A_HUMAN-Phosphoserine66 relationship: location_of CCO:B0068898 ! NU107_HUMAN-Phosphothreonine64 relationship: location_of CCO:B0068907 ! NU133_HUMAN-Phosphoserine501 relationship: location_of CCO:B0068941 ! NUP98_HUMAN-Phosphoserine1060 relationship: location_of CCO:B0069702 ! RAC2_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0071534 ! TREX1_HUMAN-Phosphoserine222 relationship: part_of CCO:C0000733 ! endomembrane system [Term] id: CCO:C0000254 name: nuclear inner membrane namespace: cellular_component def: "The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope." [GOC:ma] synonym: "inner envelope" BROAD [] xref: GO:0005637 is_a: CCO:C0000897 ! organelle inner membrane is_a: CCO:C0001358 ! nuclear membrane is_a: CCO:C0001872 ! nuclear membrane part relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0048315 ! MATR3_HUMAN-Phosphoserine206 relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 relationship: location_of CCO:B0066003 ! EMD_HUMAN-Phosphotyrosine105 relationship: location_of CCO:B0067727 ! LMNB1_HUMAN-Phosphothreonine575 [Term] id: CCO:C0000255 name: lamin filament namespace: cellular_component def: "Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C." [ISBN:0198547684] synonym: "type V intermediate filament" EXACT [] xref: GO:0005638 is_a: CCO:C0000440 ! intermediate filament is_a: CCO:C0001872 ! nuclear membrane part relationship: location_of CCO:B0067727 ! LMNB1_HUMAN-Phosphothreonine575 relationship: part_of CCO:C0000261 ! nuclear lamina [Term] id: CCO:C0000256 name: integral to nuclear inner membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the nuclear inner membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:go_curators] xref: GO:0005639 is_a: CCO:C0001153 ! intrinsic to nuclear inner membrane is_a: CCO:C0001188 ! integral to organelle membrane relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0055439 ! PSN2_HUMAN [Term] id: CCO:C0000257 name: nuclear outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." [ISBN:0198547684] synonym: "outer envelope" BROAD [] synonym: "perinuclear membrane" EXACT [] xref: GO:0005640 is_a: CCO:C0001358 ! nuclear membrane is_a: CCO:C0001361 ! organelle outer membrane is_a: CCO:C0001872 ! nuclear membrane part relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0016682 ! GUC2D_HUMAN relationship: location_of CCO:B0016684 ! GUC2F_HUMAN relationship: location_of CCO:B0059078 ! DHCR7_HUMAN relationship: part_of CCO:C0001635 ! nuclear envelope-endoplasmic reticulum network [Term] id: CCO:C0000258 name: nuclear envelope lumen namespace: cellular_component def: "The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide." [GOC:ai] comment: Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'. synonym: "nuclear intermembrane space" EXACT [] synonym: "nuclear membrane lumen" RELATED [] synonym: "perinuclear space" EXACT [] xref: GO:0005641 xref: GO:0005653 is_a: CCO:C0001363 ! organelle envelope lumen is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: part_of CCO:C0000253 ! nuclear envelope [Term] id: CCO:C0000259 name: annulate lamellae namespace: cellular_component def: "Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER." [PMID:12631728] xref: GO:0005642 is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 relationship: location_of CCO:B0039463 ! IF5A1_HUMAN-Blocked amino end (Ala)2 relationship: part_of CCO:C0001635 ! nuclear envelope-endoplasmic reticulum network [Term] id: CCO:C0000260 name: nuclear pore namespace: cellular_component def: "Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined." [ISBN:0198547684] subset: goslim_pir synonym: "NPC" EXACT [] synonym: "nuclear pore complex" EXACT [] synonym: "nuclear pore membrane protein" NARROW [] xref: GO:0005643 xref: GO:0005644 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001872 ! nuclear membrane part is_a: CCO:C0001978 ! pore complex relationship: location_of CCO:B0005409 ! IMB1_HUMAN relationship: location_of CCO:B0005661 ! IPO7_HUMAN relationship: location_of CCO:B0005662 ! XPO2_HUMAN relationship: location_of CCO:B0005663 ! TNPO1_HUMAN relationship: location_of CCO:B0005697 ! IMA5_HUMAN relationship: location_of CCO:B0006067 ! NTF2_HUMAN relationship: location_of CCO:B0012377 ! IMA2_HUMAN-Phosphoserine490 relationship: location_of CCO:B0012378 ! IMA3_HUMAN-Phosphoserine60 relationship: location_of CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0014272 ! SUMO1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 relationship: location_of CCO:B0018046 ! NXF1_HUMAN relationship: location_of CCO:B0020040 ! A3RLL6_HUMAN relationship: location_of CCO:B0020529 ! IMA7_HUMAN relationship: location_of CCO:B0021714 ! N62CL_HUMAN relationship: location_of CCO:B0021718 ! NUP62_HUMAN relationship: location_of CCO:B0024299 ! IPO11_HUMAN relationship: location_of CCO:B0024778 ! TNPO2_HUMAN relationship: location_of CCO:B0036139 ! SENP2_HUMAN relationship: location_of CCO:B0039463 ! IF5A1_HUMAN-Blocked amino end (Ala)2 relationship: location_of CCO:B0039472 ! IMA1_HUMAN-Phosphothreonine3 relationship: location_of CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: location_of CCO:B0040253 ! IMA4_HUMAN relationship: location_of CCO:B0050581 ! IPO8_HUMAN relationship: location_of CCO:B0054664 ! O75761_HUMAN relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0055487 ! NUPL_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0062772 ! DD19A_HUMAN relationship: location_of CCO:B0062780 ! NUP54_HUMAN relationship: location_of CCO:B0062870 ! IPO13_HUMAN relationship: location_of CCO:B0064683 ! DD19B_HUMAN-Phosphoserine86 relationship: location_of CCO:B0067121 ! IPO9_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068898 ! NU107_HUMAN-Phosphothreonine64 relationship: location_of CCO:B0068907 ! NU133_HUMAN-Phosphoserine501 relationship: location_of CCO:B0068941 ! NUP98_HUMAN-Phosphoserine1060 relationship: location_of CCO:B0071891 ! XPO7_HUMAN-Phosphotyrosine58 [Term] id: CCO:C0000261 name: nuclear lamina namespace: cellular_component def: "The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0716731363] xref: GO:0005652 is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001513 ! PCNA_HUMAN relationship: part_of CCO:C0000254 ! nuclear inner membrane [Term] id: CCO:C0000262 name: nucleoplasm namespace: cellular_component def: "That part of the nuclear content other than the chromosomes or the nucleolus." [GOC:ma, ISBN:0124325653] subset: goslim_generic subset: goslim_plant xref: GO:0005654 is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001346 ! CDC7_HUMAN relationship: location_of CCO:B0001352 ! E2F3_HUMAN relationship: location_of CCO:B0001354 ! UBE2C_HUMAN relationship: location_of CCO:B0001410 ! CCNT1_HUMAN relationship: location_of CCO:B0001426 ! CC45L_HUMAN relationship: location_of CCO:B0001451 ! YETS4_HUMAN relationship: location_of CCO:B0001481 ! HSP1_HUMAN relationship: location_of CCO:B0001482 ! PRM2_HUMAN relationship: location_of CCO:B0001513 ! PCNA_HUMAN relationship: location_of CCO:B0001519 ! CCNB1_HUMAN relationship: location_of CCO:B0001526 ! H2AX_HUMAN relationship: location_of CCO:B0001538 ! CCNA2_HUMAN relationship: location_of CCO:B0001543 ! TAF1_HUMAN relationship: location_of CCO:B0001562 ! RFA1_HUMAN relationship: location_of CCO:B0001564 ! DPOD1_HUMAN relationship: location_of CCO:B0001565 ! MK01_HUMAN relationship: location_of CCO:B0001577 ! MPIP2_HUMAN relationship: location_of CCO:B0001585 ! TF2H1_HUMAN relationship: location_of CCO:B0001588 ! MCM5_HUMAN relationship: location_of CCO:B0001589 ! MCM7_HUMAN relationship: location_of CCO:B0001591 ! PHB_HUMAN relationship: location_of CCO:B0001599 ! CDN1A_HUMAN relationship: location_of CCO:B0001621 ! RAD52_HUMAN relationship: location_of CCO:B0001647 ! CDK9_HUMAN relationship: location_of CCO:B0001649 ! BRCA2_HUMAN relationship: location_of CCO:B0001653 ! MAT1_HUMAN relationship: location_of CCO:B0001686 ! CKS1_HUMAN relationship: location_of CCO:B0001712 ! MDM2_HUMAN relationship: location_of CCO:B0001721 ! RAD51_HUMAN relationship: location_of CCO:B0001732 ! SNF5_HUMAN relationship: location_of CCO:B0001733 ! CDC20_HUMAN relationship: location_of CCO:B0001744 ! DUS4_HUMAN relationship: location_of CCO:B0001756 ! ATR_HUMAN relationship: location_of CCO:B0001759 ! CUL1_HUMAN relationship: location_of CCO:B0001776 ! TFDP1_HUMAN relationship: location_of CCO:B0001781 ! E2F2_HUMAN relationship: location_of CCO:B0001804 ! E2F5_HUMAN relationship: location_of CCO:B0001817 ! E2F4_HUMAN relationship: location_of CCO:B0001966 ! CD2A2_HUMAN relationship: location_of CCO:B0002019 ! PCAF_HUMAN relationship: location_of CCO:B0002056 ! MPPH1_HUMAN relationship: location_of CCO:B0002060 ! NEB2_HUMAN relationship: location_of CCO:B0002078 ! PMYT1_HUMAN relationship: location_of CCO:B0002177 ! APC11_HUMAN relationship: location_of CCO:B0002205 ! MUTYH_HUMAN relationship: location_of CCO:B0002210 ! MCM8_HUMAN relationship: location_of CCO:B0002213 ! APC7_HUMAN relationship: location_of CCO:B0002215 ! APC4_HUMAN relationship: location_of CCO:B0002221 ! FBX5_HUMAN relationship: location_of CCO:B0002230 ! APC10_HUMAN relationship: location_of CCO:B0005322 ! SMAD4_HUMAN relationship: location_of CCO:B0005345 ! XPA_HUMAN relationship: location_of CCO:B0005389 ! ORC4_HUMAN relationship: location_of CCO:B0005390 ! ORC5_HUMAN relationship: location_of CCO:B0005391 ! MCM4_HUMAN relationship: location_of CCO:B0005409 ! IMB1_HUMAN relationship: location_of CCO:B0005415 ! SMRD1_HUMAN relationship: location_of CCO:B0005417 ! SMRC2_HUMAN relationship: location_of CCO:B0005418 ! SMRC1_HUMAN relationship: location_of CCO:B0005419 ! SMRD2_HUMAN relationship: location_of CCO:B0005481 ! TBP_HUMAN relationship: location_of CCO:B0005495 ! RUXG_HUMAN relationship: location_of CCO:B0005501 ! RFA3_HUMAN relationship: location_of CCO:B0005503 ! POTE1_HUMAN relationship: location_of CCO:B0005504 ! ACD_HUMAN relationship: location_of CCO:B0005507 ! PRI1_HUMAN relationship: location_of CCO:B0005509 ! DPOA2_HUMAN relationship: location_of CCO:B0005512 ! AKT1_HUMAN relationship: location_of CCO:B0005587 ! TOP1_HUMAN relationship: location_of CCO:B0005621 ! P80C_HUMAN relationship: location_of CCO:B0005634 ! SKP1_HUMAN relationship: location_of CCO:B0005667 ! ELOC_HUMAN relationship: location_of CCO:B0005882 ! DPOD4_HUMAN relationship: location_of CCO:B0005883 ! DPOD2_HUMAN relationship: location_of CCO:B0005884 ! DPOD3_HUMAN relationship: location_of CCO:B0005892 ! MK11_HUMAN relationship: location_of CCO:B0005904 ! DPOE2_HUMAN relationship: location_of CCO:B0005943 ! APTX_HUMAN relationship: location_of CCO:B0005981 ! TRI27_HUMAN relationship: location_of CCO:B0006100 ! RPB3_HUMAN relationship: location_of CCO:B0006105 ! RFC5_HUMAN relationship: location_of CCO:B0006224 ! RECQ5_HUMAN relationship: location_of CCO:B0010521 ! ANC2_HUMAN-Phosphoserine218 relationship: location_of CCO:B0010653 ! ATM_HUMAN-Phosphothreonine72 relationship: location_of CCO:B0010694 ! ATRIP_HUMAN-Phosphoserine518 relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 relationship: location_of CCO:B0010903 ! CAF1B_HUMAN-Phosphothreonine495 relationship: location_of CCO:B0010965 ! CBX1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0010993 ! CCNE1_HUMAN-Phosphothreonine77 relationship: location_of CCO:B0010997 ! CCNE2_HUMAN-Phosphothreonine392 relationship: location_of CCO:B0011000 ! CCNH_HUMAN-Phosphothreonine315 relationship: location_of CCO:B0011007 ! CCNT2_HUMAN-Phosphoserine480 relationship: location_of CCO:B0011054 ! CDC16_HUMAN-Phosphoserine560 relationship: location_of CCO:B0011061 ! CDC23_HUMAN-Phosphothreonine556 relationship: location_of CCO:B0011066 ! CDC26_HUMAN-Phosphoserine78 relationship: location_of CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: location_of CCO:B0011078 ! CDC2_HUMAN-Phosphothreonine14 relationship: location_of CCO:B0011087 ! CDC6_HUMAN-Phosphothreonine166 relationship: location_of CCO:B0011105 ! CDK2_HUMAN-Phosphotyrosine19 relationship: location_of CCO:B0011112 ! CDK4_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0011119 ! CDK7_HUMAN-Phosphothreonine170 relationship: location_of CCO:B0011129 ! CDT1_HUMAN-Phosphoserine318 relationship: location_of CCO:B0011213 ! CHK1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0011348 ! CREB1_HUMAN-Phosphoserine142 relationship: location_of CCO:B0011456 ! DDB1_HUMAN-Phosphoserine766 relationship: location_of CCO:B0011457 ! DDB2_HUMAN-Phosphoserine24 relationship: location_of CCO:B0011519 ! DKC1_HUMAN-Phosphoserine513 relationship: location_of CCO:B0011577 ! DPOE1_HUMAN-Phosphoserine1940 relationship: location_of CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 relationship: location_of CCO:B0011620 ! E2F1_HUMAN-Phosphoserine375 relationship: location_of CCO:B0011679 ! ELOB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011719 ! EPC1_HUMAN-Phosphoserine357 relationship: location_of CCO:B0011752 ! ERCC5_HUMAN-Phosphoserine384 relationship: location_of CCO:B0011912 ! FZR_HUMAN-Phosphoserine151 relationship: location_of CCO:B0011928 ! GEMI_HUMAN-Phosphoserine64 relationship: location_of CCO:B0012250 ! HNRPK_HUMAN-Omega-N-methylated arginine296 relationship: location_of CCO:B0012377 ! IMA2_HUMAN-Phosphoserine490 relationship: location_of CCO:B0012594 ! KIF23_HUMAN-Phosphoserine682 relationship: location_of CCO:B0012646 ! KS6B2_HUMAN-Phosphoserine356 relationship: location_of CCO:B0012651 ! KU70_HUMAN-Phosphoserine51 relationship: location_of CCO:B0012656 ! KU86_HUMAN-Phosphothreonine715 relationship: location_of CCO:B0012803 ! MCM10_HUMAN-Phosphothreonine85 relationship: location_of CCO:B0012807 ! MCM2_HUMAN-Phosphoserine27 relationship: location_of CCO:B0012814 ! MCM3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012838 ! MCM6_HUMAN-Phosphothreonine791 relationship: location_of CCO:B0012841 ! MCRS1_HUMAN-Phosphoserine108 relationship: location_of CCO:B0012863 ! MDC1_HUMAN-Phosphothreonine523 relationship: location_of CCO:B0012943 ! MK03_HUMAN-Phosphotyrosine204 relationship: location_of CCO:B0012984 ! MPIP1_HUMAN-Phosphoserine124 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0013164 ! NFKB2_HUMAN-Phosphoserine713 relationship: location_of CCO:B0013334 ! ORC3_HUMAN-Phosphoserine208 relationship: location_of CCO:B0013336 ! ORC6_HUMAN-Phosphothreonine195 relationship: location_of CCO:B0013571 ! PLK1_HUMAN-Phosphoserine335 relationship: location_of CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: location_of CCO:B0013612 ! PRI2_HUMAN-Phosphotyrosine381 relationship: location_of CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013804 ! RB_HUMAN-Phosphothreonine826 relationship: location_of CCO:B0013823 ! RFA2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013831 ! RFC1_HUMAN-Phosphothreonine110 relationship: location_of CCO:B0013910 ! ROA1_HUMAN-Phosphoserine4 relationship: location_of CCO:B0013930 ! RPAC1_HUMAN-Phosphotyrosine33 relationship: location_of CCO:B0014187 ! SPT5H_HUMAN-Phosphothreonine775 relationship: location_of CCO:B0014221 ! SSRP1_HUMAN-Phosphoserine444 relationship: location_of CCO:B0014280 ! T2FA_HUMAN-Phosphoserine307 relationship: location_of CCO:B0014328 ! TE2IP_HUMAN-Phosphoserine154 relationship: location_of CCO:B0014336 ! TERF2_HUMAN-Phosphoserine380 relationship: location_of CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: location_of CCO:B0014694 ! WEE1_HUMAN-Phosphoserine642 relationship: location_of CCO:B0014698 ! WRN_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0014709 ! XPC_HUMAN-Phosphoserine347 relationship: location_of CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 relationship: location_of CCO:B0015270 ! DFFB_HUMAN relationship: location_of CCO:B0015646 ! ERCC1_HUMAN relationship: location_of CCO:B0016326 ! AAKG2_HUMAN relationship: location_of CCO:B0017957 ! RFC4_HUMAN relationship: location_of CCO:B0018285 ! TF2H2_HUMAN relationship: location_of CCO:B0018508 ! HXK4_HUMAN relationship: location_of CCO:B0018951 ! ATF6A_HUMAN relationship: location_of CCO:B0019365 ! TAF5_HUMAN relationship: location_of CCO:B0019462 ! UB2D1_HUMAN relationship: location_of CCO:B0021709 ! RPAC2_HUMAN relationship: location_of CCO:B0023192 ! SMD1_HUMAN relationship: location_of CCO:B0023973 ! TF2H3_HUMAN relationship: location_of CCO:B0026248 ! ERCC2_HUMAN relationship: location_of CCO:B0026279 ! IF3EI_HUMAN relationship: location_of CCO:B0028502 ! ERCC3_HUMAN relationship: location_of CCO:B0030933 ! DNA2L_HUMAN relationship: location_of CCO:B0030954 ! RPB4_HUMAN relationship: location_of CCO:B0031342 ! MYO16_HUMAN-Phosphotyrosine1432 relationship: location_of CCO:B0032537 ! SP16H_HUMAN relationship: location_of CCO:B0032841 ! DBF4A_HUMAN-Phosphoserine539 relationship: location_of CCO:B0032858 ! TAF10_HUMAN-N6-methyllysine189 relationship: location_of CCO:B0035198 ! MK14_HUMAN-Phosphotyrosine182 relationship: location_of CCO:B0035406 ! POLH_HUMAN-Phosphoserine380 relationship: location_of CCO:B0035539 ! RD23B_HUMAN-Phosphoserine160 relationship: location_of CCO:B0035541 ! RFC3_HUMAN-Phosphoserine125 relationship: location_of CCO:B0035829 ! WDHD1_HUMAN-Phosphoserine374 relationship: location_of CCO:B0035836 ! XRCC1_HUMAN-Phosphoserine266 relationship: location_of CCO:B0036627 ! RFC2_HUMAN relationship: location_of CCO:B0038317 ! TAF13_HUMAN relationship: location_of CCO:B0039472 ! IMA1_HUMAN-Phosphothreonine3 relationship: location_of CCO:B0039600 ! PTBP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0039636 ! RPB1_HUMAN-Phosphotyrosine1923 relationship: location_of CCO:B0041114 ! APC1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0041125 ! APC5_HUMAN-Phosphoserine217 relationship: location_of CCO:B0041139 ! H4_HUMAN-Phosphoserine2 relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041207 ! TF65_HUMAN-N6-acetyllysine122 relationship: location_of CCO:B0041248 ! UB2E1_HUMAN relationship: location_of CCO:B0041548 ! SYF1_HUMAN relationship: location_of CCO:B0043438 ! RUXF_HUMAN relationship: location_of CCO:B0043492 ! RSMB_HUMAN-Omega-N-methylated arginine112 relationship: location_of CCO:B0043792 ! TTF1_HUMAN-Phosphoserine240 relationship: location_of CCO:B0048182 ! CCND1_HUMAN-Phosphotyrosine226 relationship: location_of CCO:B0048483 ! T2AG_HUMAN relationship: location_of CCO:B0049269 ! TF2H4_HUMAN relationship: location_of CCO:B0049473 ! RPA2_HUMAN relationship: location_of CCO:B0049689 ! ATX3_HUMAN relationship: location_of CCO:B0051010 ! SPT4H_HUMAN relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 relationship: location_of CCO:B0054414 ! SMAD9_HUMAN relationship: location_of CCO:B0054905 ! DPOLB_HUMAN relationship: location_of CCO:B0055004 ! SKI_HUMAN relationship: location_of CCO:B0055150 ! NR4A1_HUMAN relationship: location_of CCO:B0055194 ! APEX1_HUMAN relationship: location_of CCO:B0055209 ! T2EB_HUMAN relationship: location_of CCO:B0055351 ! CASP3_HUMAN relationship: location_of CCO:B0055370 ! NKX21_HUMAN relationship: location_of CCO:B0055440 ! TAF6_HUMAN relationship: location_of CCO:B0055511 ! RPAB4_HUMAN relationship: location_of CCO:B0055529 ! ELL_HUMAN relationship: location_of CCO:B0055622 ! RPAB5_HUMAN relationship: location_of CCO:B0055725 ! ERCC6_HUMAN relationship: location_of CCO:B0055771 ! PAX8_HUMAN relationship: location_of CCO:B0055887 ! ERCC8_HUMAN relationship: location_of CCO:B0055930 ! TDG_HUMAN relationship: location_of CCO:B0056009 ! IRF3_HUMAN relationship: location_of CCO:B0056072 ! TAF11_HUMAN relationship: location_of CCO:B0056075 ! TAF1A_HUMAN relationship: location_of CCO:B0056172 ! IF16_HUMAN relationship: location_of CCO:B0056366 ! TAF1B_HUMAN relationship: location_of CCO:B0056941 ! SMRD3_HUMAN relationship: location_of CCO:B0057376 ! NELFD_HUMAN relationship: location_of CCO:B0057425 ! AL2S8_HUMAN relationship: location_of CCO:B0058011 ! NELFB_HUMAN relationship: location_of CCO:B0058088 ! TAF4B_HUMAN relationship: location_of CCO:B0058159 ! ISG20_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0059249 ! POLI_HUMAN relationship: location_of CCO:B0062780 ! NUP54_HUMAN relationship: location_of CCO:B0062979 ! GEMI5_HUMAN relationship: location_of CCO:B0063016 ! NCBP2_HUMAN relationship: location_of CCO:B0063138 ! RPAB3_HUMAN relationship: location_of CCO:B0063165 ! RPB11_HUMAN relationship: location_of CCO:B0063166 ! RPB7_HUMAN relationship: location_of CCO:B0063167 ! RPAB1_HUMAN relationship: location_of CCO:B0063168 ! RPB2_HUMAN relationship: location_of CCO:B0063245 ! GCKR_HUMAN relationship: location_of CCO:B0063415 ! GEMI7_HUMAN relationship: location_of CCO:B0063661 ! ATX1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0064392 ! CLSPN_HUMAN-Phosphoserine83 relationship: location_of CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: location_of CCO:B0064744 ! DFFA_HUMAN-Phosphoserine315 relationship: location_of CCO:B0064803 ! DNLI1_HUMAN-Phosphoserine66 relationship: location_of CCO:B0064811 ! DNLI3_HUMAN-Phosphothreonine122 relationship: location_of CCO:B0064906 ! DUS6_HUMAN-Phosphoserine331 relationship: location_of CCO:B0065041 ! ELOA1_HUMAN-Phosphoserine125 relationship: location_of CCO:B0065241 ! AAKB2_HUMAN-Phosphoserine183 relationship: location_of CCO:B0065258 ! AAPK2_HUMAN-Phosphoserine173 relationship: location_of CCO:B0066315 ! FUSIP_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0066440 ! GEMI2_HUMAN-Phosphothreonine48 relationship: location_of CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 relationship: location_of CCO:B0066454 ! GIT2_HUMAN-Phosphothreonine401 relationship: location_of CCO:B0067455 ! KS6A1_HUMAN-Phosphoserine380 relationship: location_of CCO:B0067458 ! KS6A2_HUMAN-Phosphoserine218 relationship: location_of CCO:B0067465 ! KS6A3_HUMAN-Phosphothreonine231 relationship: location_of CCO:B0067479 ! KS6A5_HUMAN-Phosphoserine752 relationship: location_of CCO:B0068161 ! MGMT_HUMAN-Phosphoserine201 relationship: location_of CCO:B0068256 ! MPIP3_HUMAN-Phosphoserine57 relationship: location_of CCO:B0068286 ! MRE11_HUMAN-Phosphoserine649 relationship: location_of CCO:B0068452 ! NCBP1_HUMAN-Phosphoserine22 relationship: location_of CCO:B0068563 ! NELFA_HUMAN-Phosphoserine233 relationship: location_of CCO:B0068569 ! NELFE_HUMAN-Phosphoserine131 relationship: location_of CCO:B0068667 ! NFKB1_HUMAN-Phosphoserine907 relationship: location_of CCO:B0068941 ! NUP98_HUMAN-Phosphoserine1060 relationship: location_of CCO:B0068985 ! ORC1_HUMAN-Phosphothreonine337 relationship: location_of CCO:B0068990 ! ORC2_HUMAN-Phosphoserine280 relationship: location_of CCO:B0069525 ! PRKDC_HUMAN-Phosphoserine4026 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069815 ! RBM39_HUMAN-Phosphoserine127 relationship: location_of CCO:B0070150 ! RPAB2_HUMAN-Phosphoserine2 relationship: location_of CCO:B0070158 ! RPB9_HUMAN-Phosphoserine73 relationship: location_of CCO:B0070193 ! RRN3_HUMAN-Phosphoserine44 relationship: location_of CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0070598 ! SMAD2_HUMAN-Phosphoserine255 relationship: location_of CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 relationship: location_of CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 relationship: location_of CCO:B0070623 ! SMCA2_HUMAN-Phosphoserine1377 relationship: location_of CCO:B0070630 ! SMCA4_HUMAN-Phosphoserine613 relationship: location_of CCO:B0070643 ! SMCA5_HUMAN-Phosphoserine755 relationship: location_of CCO:B0070644 ! SMD2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070647 ! SMN_HUMAN-Phosphothreonine25 relationship: location_of CCO:B0071070 ! T2EA_HUMAN-Phosphoserine268 relationship: location_of CCO:B0071071 ! T2FB_HUMAN-Phosphoserine142 relationship: location_of CCO:B0071085 ! TAF12_HUMAN-Phosphothreonine43 relationship: location_of CCO:B0071117 ! TAF9_HUMAN-Phosphoserine181 relationship: location_of CCO:B0071262 ! TCEA1_HUMAN-Phosphothreonine108 relationship: location_of CCO:B0071340 ! TERF1_HUMAN-Phosphoserine435 relationship: location_of CCO:B0071342 ! TERT_HUMAN-Phosphothreonine1113 relationship: location_of CCO:B0071358 ! TF2AA_HUMAN-Phosphoserine281 relationship: location_of CCO:B0071361 ! TF2B_HUMAN-Phosphoserine76 relationship: location_of CCO:B0071407 ! TINF2_HUMAN-Phosphoserine295 relationship: location_of CCO:B0071667 ! UBF1_HUMAN-Phosphoserine484 relationship: location_of CCO:B0072196 ! ZN638_HUMAN-Phosphoserine605 relationship: part_of CCO:C0001373 ! nuclear lumen [Term] id: CCO:C0000263 name: nucleolar ribonuclease P complex namespace: cellular_component def: "A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules." [GOC:mah, PMID:12045094] synonym: "nucleolar RNase P complex" EXACT [] xref: GO:0005655 is_a: CCO:C0001042 ! multimeric ribonuclease P complex is_a: CCO:C0001871 ! nucleolar part [Term] id: CCO:C0000264 name: pre-replicative complex namespace: cellular_component def: "A multiprotein complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins." [PMID:15222894] synonym: "pre-RC" EXACT [] xref: GO:0005656 is_a: CCO:C0001494 ! protein-DNA complex is_a: CCO:C0001870 ! nucleoplasm part [Term] id: CCO:C0000265 name: replication fork namespace: cellular_component def: "The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes." [GOC:mah, ISBN:0198547684] subset: gosubset_prok synonym: "replication focus" RELATED [] xref: GO:0005657 is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0001513 ! PCNA_HUMAN relationship: location_of CCO:B0001526 ! H2AX_HUMAN relationship: location_of CCO:B0001603 ! BCL6_HUMAN relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0011129 ! CDT1_HUMAN-Phosphoserine318 relationship: location_of CCO:B0011213 ! CHK1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0012159 ! HDAC2_HUMAN-Phosphoserine394 relationship: location_of CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: location_of CCO:B0034711 ! DNMT1_HUMAN-Phosphoserine127 [Term] id: CCO:C0000266 name: alpha DNA polymerase:primase complex namespace: cellular_component def: "A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis." [GOC:mah, PMID:11395402] synonym: "DNA polymerase alpha:primase complex" EXACT [] synonym: "heterotetrameric polymerase alpha holoenzyme" EXACT [] synonym: "pol-prim" RELATED [] synonym: "primosome" BROAD [] xref: GO:0005658 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0005507 ! PRI1_HUMAN relationship: location_of CCO:B0005509 ! DPOA2_HUMAN relationship: location_of CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 relationship: location_of CCO:B0012814 ! MCM3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013612 ! PRI2_HUMAN-Phosphotyrosine381 relationship: location_of CCO:B0056354 ! Q53F98_HUMAN relationship: location_of CCO:B0066792 ! HELB_HUMAN-Phosphoserine709 relationship: part_of CCO:C0001798 ! nuclear replisome [Term] id: CCO:C0000267 name: DNA replication factor A complex namespace: cellular_component def: "A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa." [PMID:9242902] synonym: "replication protein A" EXACT [] synonym: "RPA" EXACT [] synonym: "single-stranded DNA-binding protein complex" RELATED [] synonym: "SSB" RELATED [] xref: GO:0005662 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001562 ! RFA1_HUMAN relationship: location_of CCO:B0005501 ! RFA3_HUMAN relationship: location_of CCO:B0013823 ! RFA2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0017945 ! PURB_HUMAN relationship: location_of CCO:B0055880 ! RFA4_HUMAN relationship: location_of CCO:B0069637 ! PURA_HUMAN-Phosphoserine8 relationship: part_of CCO:C0001798 ! nuclear replisome [Term] id: CCO:C0000268 name: DNA replication factor C complex namespace: cellular_component def: "A complex of five polypeptides in eukaryotes, and two in prokaryotes, that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase." [PMID:14614842, PMID:14646196, PMID:16172520] subset: goslim_pir subset: gosubset_prok synonym: "activator 1 complex" EXACT [] synonym: "RFC complex" EXACT [] xref: GO:0005663 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0001513 ! PCNA_HUMAN relationship: location_of CCO:B0006105 ! RFC5_HUMAN relationship: location_of CCO:B0013831 ! RFC1_HUMAN-Phosphothreonine110 relationship: location_of CCO:B0017050 ! Q6LES9_HUMAN relationship: location_of CCO:B0017957 ! RFC4_HUMAN relationship: location_of CCO:B0035541 ! RFC3_HUMAN-Phosphoserine125 relationship: location_of CCO:B0036627 ! RFC2_HUMAN relationship: part_of CCO:C0000265 ! replication fork [Term] id: CCO:C0000269 name: nuclear origin of replication recognition complex namespace: cellular_component def: "A multisubunit complex that is located at the replication origins of a chromosome in the nucleus." [GOC:elh] synonym: "eukaryotic ORC" EXACT [] synonym: "nuclear ORC" EXACT [] xref: GO:0005664 is_a: CCO:C0000135 ! origin recognition complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0012807 ! MCM2_HUMAN-Phosphoserine27 relationship: location_of CCO:B0013334 ! ORC3_HUMAN-Phosphoserine208 relationship: location_of CCO:B0013336 ! ORC6_HUMAN-Phosphothreonine195 relationship: location_of CCO:B0054744 ! O95268_HUMAN relationship: location_of CCO:B0058531 ! REPI1_HUMAN relationship: location_of CCO:B0058749 ! Q9H806_HUMAN relationship: location_of CCO:B0068990 ! ORC2_HUMAN-Phosphoserine280 [Term] id: CCO:C0000270 name: DNA-directed RNA polymerase II, core complex namespace: cellular_component def: "RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template." [GOC:krc, GOC:mtg_sensu] xref: GO:0005665 is_a: CCO:C0001870 ! nucleoplasm part is_a: CCO:C0002015 ! nuclear DNA-directed RNA polymerase complex relationship: location_of CCO:B0005783 ! MED21_HUMAN relationship: location_of CCO:B0006031 ! PRGC1_HUMAN relationship: location_of CCO:B0030954 ! RPB4_HUMAN relationship: location_of CCO:B0039636 ! RPB1_HUMAN-Phosphotyrosine1923 relationship: location_of CCO:B0055023 ! HCLS1_HUMAN relationship: location_of CCO:B0055622 ! RPAB5_HUMAN relationship: location_of CCO:B0063165 ! RPB11_HUMAN relationship: location_of CCO:B0063167 ! RPAB1_HUMAN relationship: location_of CCO:B0063168 ! RPB2_HUMAN relationship: location_of CCO:B0070096 ! RMP_HUMAN-Phosphothreonine242 relationship: location_of CCO:B0072053 ! ZN148_HUMAN-Phosphoserine306 relationship: location_of CCO:B0072087 ! ZN281_HUMAN-Phosphoserine484 relationship: location_of CCO:B0072233 ! ZN768_HUMAN-Phosphoserine18 relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000271 name: DNA-directed RNA polymerase III complex namespace: cellular_component def: "RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template." [GOC:krc, GOC:mtg_sensu] synonym: "DNA-directed RNA polymerase III activity" RELATED [] xref: GO:0005666 is_a: CCO:C0001870 ! nucleoplasm part is_a: CCO:C0002015 ! nuclear DNA-directed RNA polymerase complex relationship: location_of CCO:B0006101 ! RPC6_HUMAN relationship: location_of CCO:B0054428 ! RPC7_HUMAN relationship: location_of CCO:B0059323 ! RPC10_HUMAN relationship: location_of CCO:B0070159 ! RPC3_HUMAN-Phosphoserine194 [Term] id: CCO:C0000272 name: transcription factor complex namespace: cellular_component def: "Any complex, distinct from RNA polymerase, including one or more polypeptides capable of binding DNA at promoters or at cis-acting regulatory sequences, and regulating transcription." [GOC:mah] subset: goslim_pir xref: GO:0005667 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0001317 ! E2F8_HUMAN relationship: location_of CCO:B0001352 ! E2F3_HUMAN relationship: location_of CCO:B0001429 ! E2F6_HUMAN relationship: location_of CCO:B0001431 ! SUPT3_HUMAN relationship: location_of CCO:B0001776 ! TFDP1_HUMAN relationship: location_of CCO:B0001777 ! TFDP2_HUMAN relationship: location_of CCO:B0001781 ! E2F2_HUMAN relationship: location_of CCO:B0001804 ! E2F5_HUMAN relationship: location_of CCO:B0001817 ! E2F4_HUMAN relationship: location_of CCO:B0001833 ! Q499G5_HUMAN relationship: location_of CCO:B0001849 ! TFDP3_HUMAN relationship: location_of CCO:B0001854 ! Q5JSB5_HUMAN relationship: location_of CCO:B0001855 ! Q5JSB6_HUMAN relationship: location_of CCO:B0001912 ! PMF1_HUMAN relationship: location_of CCO:B0001917 ! Q6Q9Z6_HUMAN relationship: location_of CCO:B0002031 ! E2F7_HUMAN relationship: location_of CCO:B0002251 ! ATF5_HUMAN relationship: location_of CCO:B0005322 ! SMAD4_HUMAN relationship: location_of CCO:B0005715 ! ITF2_HUMAN relationship: location_of CCO:B0005782 ! MED7_HUMAN relationship: location_of CCO:B0005793 ! MED23_HUMAN relationship: location_of CCO:B0005893 ! NCOA6_HUMAN relationship: location_of CCO:B0006033 ! ARNT2_HUMAN relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0011620 ! E2F1_HUMAN-Phosphoserine375 relationship: location_of CCO:B0011717 ! EPAS1_HUMAN-Phosphothreonine840 relationship: location_of CCO:B0012195 ! HIF1A_HUMAN-3-hydroxyasparagine803 relationship: location_of CCO:B0012449 ! JUN_HUMAN-Phosphoserine63 relationship: location_of CCO:B0012651 ! KU70_HUMAN-Phosphoserine51 relationship: location_of CCO:B0012890 ! MED17_HUMAN-Phosphoserine37 relationship: location_of CCO:B0013463 ! PDLI1_HUMAN-Phosphotyrosine321 relationship: location_of CCO:B0013804 ! RB_HUMAN-Phosphothreonine826 relationship: location_of CCO:B0014560 ! TYY1_HUMAN-Phosphoserine184 relationship: location_of CCO:B0016699 ! FOXF1_HUMAN relationship: location_of CCO:B0016719 ! FOXF2_HUMAN relationship: location_of CCO:B0016727 ! FOXE3_HUMAN relationship: location_of CCO:B0024344 ! Q9UG28_HUMAN relationship: location_of CCO:B0024873 ! NR6A1_HUMAN relationship: location_of CCO:B0025086 ! Q6Q9Z7_HUMAN relationship: location_of CCO:B0026530 ! NPAS2_HUMAN relationship: location_of CCO:B0026531 ! CLOCK_HUMAN relationship: location_of CCO:B0029479 ! LMO4_HUMAN relationship: location_of CCO:B0032261 ! TEAD3_HUMAN relationship: location_of CCO:B0032268 ! TEAD2_HUMAN relationship: location_of CCO:B0032489 ! MEIS1_HUMAN relationship: location_of CCO:B0033733 ! MAFB_HUMAN relationship: location_of CCO:B0034126 ! RARG_HUMAN relationship: location_of CCO:B0038317 ! TAF13_HUMAN relationship: location_of CCO:B0041207 ! TF65_HUMAN-N6-acetyllysine122 relationship: location_of CCO:B0049069 ! ONEC3_HUMAN relationship: location_of CCO:B0050549 ! Q96KX3_HUMAN relationship: location_of CCO:B0052826 ! TCP4_HUMAN-Phosphoserine56 relationship: location_of CCO:B0052829 ! TF3B_HUMAN-Phosphoserine433 relationship: location_of CCO:B0053746 ! A3KN61_HUMAN relationship: location_of CCO:B0054151 ! A9J6M5_HUMAN relationship: location_of CCO:B0054269 ! B1APE1_HUMAN relationship: location_of CCO:B0054270 ! B1APE2_HUMAN relationship: location_of CCO:B0054311 ! BMAL1_HUMAN relationship: location_of CCO:B0054406 ! SMAD7_HUMAN relationship: location_of CCO:B0054414 ! SMAD9_HUMAN relationship: location_of CCO:B0054456 ! CRX_HUMAN relationship: location_of CCO:B0054488 ! SMAD6_HUMAN relationship: location_of CCO:B0054622 ! PROP1_HUMAN relationship: location_of CCO:B0054833 ! FOS_HUMAN relationship: location_of CCO:B0055105 ! ATF1_HUMAN relationship: location_of CCO:B0055370 ! NKX21_HUMAN relationship: location_of CCO:B0055506 ! NKX25_HUMAN relationship: location_of CCO:B0055507 ! LBX1_HUMAN relationship: location_of CCO:B0055535 ! PKNX1_HUMAN relationship: location_of CCO:B0056058 ! ANKR1_HUMAN relationship: location_of CCO:B0056069 ! SIX1_HUMAN relationship: location_of CCO:B0056274 ! Q3SYD7_HUMAN relationship: location_of CCO:B0056275 ! Q3SYD8_HUMAN relationship: location_of CCO:B0056848 ! NARGL_HUMAN relationship: location_of CCO:B0056929 ! FIGLA_HUMAN relationship: location_of CCO:B0057080 ! Q6ZV39_HUMAN relationship: location_of CCO:B0057127 ! PTF1A_HUMAN relationship: location_of CCO:B0057218 ! Q7Z7L4_HUMAN relationship: location_of CCO:B0058223 ! HES6_HUMAN relationship: location_of CCO:B0058441 ! PITX2_HUMAN relationship: location_of CCO:B0058660 ! ALX4_HUMAN relationship: location_of CCO:B0058771 ! BRF2_HUMAN relationship: location_of CCO:B0058834 ! GCM1_HUMAN relationship: location_of CCO:B0058860 ! ASCL3_HUMAN relationship: location_of CCO:B0059175 ! LEF1_HUMAN relationship: location_of CCO:B0059235 ! ABT1_HUMAN relationship: location_of CCO:B0066824 ! HMGA1_HUMAN-Phosphoserine36 relationship: location_of CCO:B0068440 ! NARG1_HUMAN-Phosphoserine855 relationship: location_of CCO:B0069784 ! RBM14_HUMAN-Phosphothreonine572 relationship: location_of CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0070598 ! SMAD2_HUMAN-Phosphoserine255 relationship: location_of CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 relationship: location_of CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 relationship: location_of CCO:B0070862 ! SRA1_HUMAN-Phosphothreonine68 relationship: location_of CCO:B0071361 ! TF2B_HUMAN-Phosphoserine76 relationship: location_of CCO:B0071833 ! WBS14_HUMAN-Phosphothreonine509 relationship: location_of CCO:B0071885 ! WWTR1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0071913 ! YAP1_HUMAN-Phosphoserine236 relationship: location_of CCO:B0072012 ! ZFHX3_HUMAN-Phosphoserine1180 [Term] id: CCO:C0000273 name: selectivity factor SL1 complex namespace: cellular_component def: "A RNA polymerase I-specific protein complex which in humans has two subunits, tata-binding protein (TBP) and TBP-associated factor 1 (TAF1)." [GOC:jl, PMID:9857193] xref: GO:0005668 is_a: CCO:C0000272 ! transcription factor complex [Term] id: CCO:C0000274 name: transcription factor TFIID complex namespace: cellular_component def: "A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters." [GOC:krc, GOC:mah, ISBN:0471953393, ISBN:0879695501] xref: GO:0005669 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0001543 ! TAF1_HUMAN relationship: location_of CCO:B0001959 ! TAF1L_HUMAN relationship: location_of CCO:B0005481 ! TBP_HUMAN relationship: location_of CCO:B0014928 ! TAF9B_HUMAN relationship: location_of CCO:B0019365 ! TAF5_HUMAN relationship: location_of CCO:B0032858 ! TAF10_HUMAN-N6-methyllysine189 relationship: location_of CCO:B0032975 ! TBPL2_HUMAN relationship: location_of CCO:B0032981 ! Q32MN6_HUMAN relationship: location_of CCO:B0038317 ! TAF13_HUMAN relationship: location_of CCO:B0053768 ! A4PBF7_HUMAN relationship: location_of CCO:B0054289 ! B1Q2X3_HUMAN relationship: location_of CCO:B0054305 ! TAF4_HUMAN relationship: location_of CCO:B0054582 ! EDF1_HUMAN relationship: location_of CCO:B0055440 ! TAF6_HUMAN relationship: location_of CCO:B0055618 ! TBPL1_HUMAN relationship: location_of CCO:B0056072 ! TAF11_HUMAN relationship: location_of CCO:B0056440 ! TAF7L_HUMAN relationship: location_of CCO:B0056606 ! Q5TBP5_HUMAN relationship: location_of CCO:B0057200 ! Q7Z6S5_HUMAN relationship: location_of CCO:B0057201 ! Q7Z6S6_HUMAN relationship: location_of CCO:B0057202 ! Q7Z6T9_HUMAN relationship: location_of CCO:B0057203 ! Q7Z6U0_HUMAN relationship: location_of CCO:B0057204 ! Q7Z6U1_HUMAN relationship: location_of CCO:B0057205 ! Q7Z6U2_HUMAN relationship: location_of CCO:B0057209 ! TAF8_HUMAN relationship: location_of CCO:B0058088 ! TAF4B_HUMAN relationship: location_of CCO:B0071085 ! TAF12_HUMAN-Phosphothreonine43 relationship: location_of CCO:B0071087 ! TAF2_HUMAN-Phosphoserine1194 relationship: location_of CCO:B0071108 ! TAF7_HUMAN-Phosphoserine227 relationship: location_of CCO:B0071117 ! TAF9_HUMAN-Phosphoserine181 relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000275 name: Ada2/Gcn5/Ada3 transcription activator complex namespace: cellular_component def: "A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins." [PMID:10637607] xref: GO:0005671 is_a: CCO:C0000011 ! histone acetyltransferase complex [Term] id: CCO:C0000276 name: transcription factor TFIIA complex namespace: cellular_component def: "A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12)." [GOC:jl, UniProtKB:P52655] xref: GO:0005672 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0048483 ! T2AG_HUMAN relationship: location_of CCO:B0059253 ! TF2AY_HUMAN relationship: location_of CCO:B0071358 ! TF2AA_HUMAN-Phosphoserine281 relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000277 name: transcription factor TFIIE complex namespace: cellular_component def: "A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH." [GOC:jl, UniProtKB:P29083] xref: GO:0005673 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0055209 ! T2EB_HUMAN relationship: location_of CCO:B0055440 ! TAF6_HUMAN relationship: location_of CCO:B0071070 ! T2EA_HUMAN-Phosphoserine268 relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000278 name: transcription factor TFIIF complex namespace: cellular_component def: "A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation." [GOC:jl, UniProtKB:P13984] xref: GO:0005674 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0014280 ! T2FA_HUMAN-Phosphoserine307 relationship: location_of CCO:B0071071 ! T2FB_HUMAN-Phosphoserine142 relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000279 name: holo TFIIH complex namespace: cellular_component def: "A complex that contains kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. In S. cerevisiae, it is composed of the 5-subunit core (Rad3p, Tfb1p, Tfb2p, Ssl1p and Tfb4p), Ssl2p, and TFIIK (Kin28p, Ccl1p, and Tfb3p). All of the subunits have equivalents in humans: the 5 subunit core is composed of XPD, p62, p55, p44, p34; the equivalent of the TFIIK subcomplex is composed of MO15, Mat1, and a cyclin; the human equivalent of Ssl2p is XPB." [GOC:krc, PMID:14500720, PMID:7813015, UniProtKB:Q13889] xref: GO:0005675 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0001585 ! TF2H1_HUMAN relationship: location_of CCO:B0011752 ! ERCC5_HUMAN-Phosphoserine384 relationship: location_of CCO:B0023973 ! TF2H3_HUMAN relationship: location_of CCO:B0026248 ! ERCC2_HUMAN relationship: location_of CCO:B0028502 ! ERCC3_HUMAN relationship: location_of CCO:B0049269 ! TF2H4_HUMAN relationship: location_of CCO:B0068243 ! MMS19_HUMAN-Phosphoserine371 relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000280 name: chromatin silencing complex namespace: cellular_component def: "Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing." [GOC:mah] xref: GO:0005677 is_a: CCO:C0000806 ! chromatin remodeling complex relationship: location_of CCO:B0017935 ! A7VJH3_HUMAN relationship: location_of CCO:B0041195 ! SIRT2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0054178 ! B0QZ35_HUMAN relationship: location_of CCO:B0056995 ! Q6ZMU6_HUMAN relationship: location_of CCO:B0056999 ! Q6ZMZ2_HUMAN relationship: location_of CCO:B0057009 ! Q6ZN34_HUMAN relationship: location_of CCO:B0057562 ! Q8NC36_HUMAN relationship: location_of CCO:B0058895 ! SIRT7_HUMAN relationship: location_of CCO:B0058924 ! SIRT3_HUMAN relationship: location_of CCO:B0058951 ! SIRT5_HUMAN relationship: location_of CCO:B0059404 ! SIRT4_HUMAN relationship: location_of CCO:B0070543 ! SIRT1_HUMAN-Phosphoserine47 relationship: location_of CCO:B0070548 ! SIRT6_HUMAN-Phosphothreonine294 [Term] id: CCO:C0000281 name: chromatin assembly complex namespace: cellular_component def: "Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure." [GOC:mah] xref: GO:0005678 is_a: CCO:C0000806 ! chromatin remodeling complex relationship: location_of CCO:B0010892 ! CAF1A_HUMAN-Phosphoserine123 relationship: location_of CCO:B0010903 ! CAF1B_HUMAN-Phosphothreonine495 relationship: location_of CCO:B0013244 ! NP1L1_HUMAN-Phosphoserine10 [Term] id: CCO:C0000282 name: anaphase-promoting complex namespace: cellular_component def: "A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B." [GOC:jh, PMID:10465783, PMID:10611969] synonym: "anaphase promoting complex" EXACT [] synonym: "APC" EXACT [] synonym: "cyclosome" EXACT [] xref: GO:0005680 is_a: CCO:C0000027 ! nuclear ubiquitin ligase complex relationship: location_of CCO:B0001380 ! ZZEF1_HUMAN relationship: location_of CCO:B0001875 ! HECD3_HUMAN relationship: location_of CCO:B0001888 ! Q5TCY3_HUMAN relationship: location_of CCO:B0001949 ! PARC_HUMAN relationship: location_of CCO:B0002177 ! APC11_HUMAN relationship: location_of CCO:B0002215 ! APC4_HUMAN relationship: location_of CCO:B0002230 ! APC10_HUMAN relationship: location_of CCO:B0011061 ! CDC23_HUMAN-Phosphothreonine556 relationship: location_of CCO:B0011066 ! CDC26_HUMAN-Phosphoserine78 relationship: location_of CCO:B0011912 ! FZR_HUMAN-Phosphoserine151 relationship: location_of CCO:B0019420 ! Q53FN2_HUMAN relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0041125 ! APC5_HUMAN-Phosphoserine217 relationship: location_of CCO:B0065913 ! CUL7_HUMAN-Phosphoserine329 [Term] id: CCO:C0000283 name: spliceosome namespace: cellular_component def: "A ribonucleoprotein complex, containing RNA and small nuclear ribonucleoproteins (snRNPs) that is assembled during the splicing of messenger RNA primary transcript to excise an intron." [ISBN:0198547684] subset: goslim_pir synonym: "spliceosome complex" EXACT [] xref: GO:0005681 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001361 ! O14835_HUMAN relationship: location_of CCO:B0001676 ! NH2L1_HUMAN relationship: location_of CCO:B0002065 ! CDC5L_HUMAN relationship: location_of CCO:B0005346 ! SK2L2_HUMAN relationship: location_of CCO:B0005495 ! RUXG_HUMAN relationship: location_of CCO:B0005593 ! CRNL1_HUMAN relationship: location_of CCO:B0005729 ! DDX5_HUMAN relationship: location_of CCO:B0005996 ! WDR57_HUMAN relationship: location_of CCO:B0006111 ! RSMN_HUMAN relationship: location_of CCO:B0012231 ! HNRPF_HUMAN-Phosphoserine161 relationship: location_of CCO:B0012250 ! HNRPK_HUMAN-Omega-N-methylated arginine296 relationship: location_of CCO:B0012707 ! LSM3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013372 ! PABP1_HUMAN-Omega-N-methylated arginine493 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0013797 ! RBM8A_HUMAN-Phosphoserine166 relationship: location_of CCO:B0013910 ! ROA1_HUMAN-Phosphoserine4 relationship: location_of CCO:B0013926 ! ROA2_HUMAN-Phosphoserine259 relationship: location_of CCO:B0014041 ! SFRS1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0014148 ! SNUT1_HUMAN-Phosphoserine596 relationship: location_of CCO:B0017947 ! PHF5A_HUMAN relationship: location_of CCO:B0023192 ! SMD1_HUMAN relationship: location_of CCO:B0026181 ! SF3B3_HUMAN relationship: location_of CCO:B0035440 ! PRP4B_HUMAN-Phosphoserine20 relationship: location_of CCO:B0035471 ! PRP8_HUMAN-Phosphothreonine1318 relationship: location_of CCO:B0035500 ! RALY_HUMAN-Phosphoserine135 relationship: location_of CCO:B0035781 ! THOC4_HUMAN-Phosphoserine183 relationship: location_of CCO:B0035820 ! U520_HUMAN-Phosphoserine1056 relationship: location_of CCO:B0039936 ! RHEB_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0041548 ! SYF1_HUMAN relationship: location_of CCO:B0043438 ! RUXF_HUMAN relationship: location_of CCO:B0043492 ! RSMB_HUMAN-Omega-N-methylated arginine112 relationship: location_of CCO:B0048277 ! HNRPC_HUMAN-Phosphoserine306 relationship: location_of CCO:B0048571 ! SNW1_HUMAN relationship: location_of CCO:B0052699 ! ROA3_HUMAN-Phosphoserine355 relationship: location_of CCO:B0052736 ! SF3B1_HUMAN-Phosphothreonine223 relationship: location_of CCO:B0054708 ! PRP6_HUMAN relationship: location_of CCO:B0055320 ! IF4A3_HUMAN relationship: location_of CCO:B0058612 ! API5_HUMAN relationship: location_of CCO:B0058807 ! NCM_HUMAN relationship: location_of CCO:B0059255 ! PPIE_HUMAN relationship: location_of CCO:B0062979 ! GEMI5_HUMAN relationship: location_of CCO:B0063003 ! SNRPA_HUMAN relationship: location_of CCO:B0063122 ! U5S1_HUMAN relationship: location_of CCO:B0063234 ! MGN_HUMAN relationship: location_of CCO:B0063276 ! CS029_HUMAN relationship: location_of CCO:B0063382 ! HNRPR_HUMAN relationship: location_of CCO:B0063415 ! GEMI7_HUMAN relationship: location_of CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: location_of CCO:B0065937 ! DDX23_HUMAN-Phosphoserine107 relationship: location_of CCO:B0066440 ! GEMI2_HUMAN-Phosphothreonine48 relationship: location_of CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 relationship: location_of CCO:B0066854 ! HNRH1_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0066865 ! HNRPG_HUMAN-Phosphoserine326 relationship: location_of CCO:B0066869 ! HNRPM_HUMAN-Phosphoserine432 relationship: location_of CCO:B0066887 ! HNRPU_HUMAN-Omega-N-methylated arginine732 relationship: location_of CCO:B0067787 ! LSM2_HUMAN-Phosphothreonine79 relationship: location_of CCO:B0069454 ! PP1R8_HUMAN-Phosphotyrosine264 relationship: location_of CCO:B0069474 ! PR38A_HUMAN-Phosphoserine279 relationship: location_of CCO:B0069547 ! PRP19_HUMAN-Phosphothreonine342 relationship: location_of CCO:B0069558 ! PRPF3_HUMAN-Phosphoserine619 relationship: location_of CCO:B0070262 ! RU17_HUMAN-Phosphotyrosine126 relationship: location_of CCO:B0070268 ! RU2A_HUMAN-Phosphoserine197 relationship: location_of CCO:B0070388 ! SF01_HUMAN-Phosphoserine20 relationship: location_of CCO:B0070394 ! SF17A_HUMAN-Phosphoserine633 relationship: location_of CCO:B0070396 ! SF3B4_HUMAN-Phosphotyrosine56 relationship: location_of CCO:B0070644 ! SMD2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070647 ! SMN_HUMAN-Phosphothreonine25 relationship: location_of CCO:B0070797 ! SPF30_HUMAN-Phosphoserine201 relationship: location_of CCO:B0071623 ! TTF2_HUMAN-Phosphoserine396 relationship: location_of CCO:B0071634 ! TXN4A_HUMAN-Phosphoserine132 relationship: location_of CCO:B0071635 ! TXN4B_HUMAN-Phosphoserine132 relationship: location_of CCO:B0071647 ! U2AF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0071653 ! U2AF2_HUMAN-Phosphoserine53 relationship: location_of CCO:B0071663 ! UAP56_HUMAN-Phosphothreonine172 [Term] id: CCO:C0000284 name: snRNP U5 namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U5; a component of both the major and minor spliceosome complexes." [GOC:krc] xref: GO:0005682 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: location_of CCO:B0005996 ! WDR57_HUMAN relationship: location_of CCO:B0035471 ! PRP8_HUMAN-Phosphothreonine1318 relationship: location_of CCO:B0035820 ! U520_HUMAN-Phosphoserine1056 relationship: location_of CCO:B0065937 ! DDX23_HUMAN-Phosphoserine107 relationship: part_of CCO:C0000286 ! U2-dependent spliceosome relationship: part_of CCO:C0000291 ! U12-dependent spliceosome [Term] id: CCO:C0000285 name: snRNP U7 namespace: cellular_component def: "A ribonucleoprotein complex, that includes the U7 snRNA, required for the 3'-end processing of replication-dependent histone pre-mRNAs." [PMID:12872004] xref: GO:0005683 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex [Term] id: CCO:C0000286 name: U2-dependent spliceosome namespace: cellular_component def: "The major (U2-dependent) spliceosome is composed of five snRNP complexes (U1, U2, U4, U5, and U6) as well as many non-snRNP proteins. It acts through many RNA-RNA, RNA-protein, and protein-protein interactions to precisely excise each intron and join the flanking exons." [PMID:11343900] synonym: "GT-AG spliceosome" EXACT [] synonym: "major (U2-dependent) spliceosome" EXACT [] synonym: "major spliceosome" EXACT [] xref: GO:0005684 is_a: CCO:C0000283 ! spliceosome [Term] id: CCO:C0000287 name: snRNP U1 namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U1; a component of the major spliceosome complex." [GOC:krc] xref: GO:0005685 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: part_of CCO:C0000286 ! U2-dependent spliceosome [Term] id: CCO:C0000288 name: snRNP U2 namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U2; a component of the major spliceosome complex." [GOC:krc] xref: GO:0005686 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: location_of CCO:B0017947 ! PHF5A_HUMAN relationship: location_of CCO:B0070268 ! RU2A_HUMAN-Phosphoserine197 relationship: part_of CCO:C0000286 ! U2-dependent spliceosome [Term] id: CCO:C0000289 name: snRNP U4 namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U4; a component of the major spliceosome complex." [GOC:krc] xref: GO:0005687 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: part_of CCO:C0000286 ! U2-dependent spliceosome [Term] id: CCO:C0000290 name: snRNP U6 namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U6; a component of the major spliceosome complex." [GOC:krc] xref: GO:0005688 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: location_of CCO:B0063157 ! LSM4_HUMAN relationship: part_of CCO:C0000286 ! U2-dependent spliceosome [Term] id: CCO:C0000291 name: U12-dependent spliceosome namespace: cellular_component def: "The minor (U12-dependent) spliceosome is composed of the snRNPs, U11, U12, U4atac, U6atac, and U5 (which is also a component of the major spliceosome). This minor form of the spliceosome is responsible for the splicing of the majority of introns with atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site." [PMID:11574683, PMID:11971955] synonym: "AT-AC spliceosome" EXACT [] synonym: "minor (U12-dependent) spliceosome complex" EXACT [] synonym: "minor spliceosome" EXACT [] xref: GO:0005689 is_a: CCO:C0000283 ! spliceosome relationship: location_of CCO:B0057517 ! PDCD7_HUMAN [Term] id: CCO:C0000292 name: snRNP U4atac namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U4atac; a component of the minor spliceosome complex." [GOC:krc] xref: GO:0005690 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: part_of CCO:C0000291 ! U12-dependent spliceosome [Term] id: CCO:C0000293 name: snRNP U6atac namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U6atac; a component of the minor spliceosome complex." [GOC:krc] xref: GO:0005691 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: part_of CCO:C0000291 ! U12-dependent spliceosome [Term] id: CCO:C0000294 name: snRNP U11 namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U11; a component of the minor spliceosome complex." [GOC:krc] xref: GO:0005692 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: part_of CCO:C0000291 ! U12-dependent spliceosome [Term] id: CCO:C0000295 name: snRNP U12 namespace: cellular_component def: "Ribonucleoprotein complex containing small nuclear RNA U12; a component of the minor spliceosome complex." [GOC:krc] xref: GO:0005693 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex relationship: part_of CCO:C0000291 ! U12-dependent spliceosome [Term] id: CCO:C0000296 name: chromosome namespace: cellular_component def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_yeast subset: gosubset_prok synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] xref: GO:0005694 is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001337 ! A6NLT8_HUMAN relationship: location_of CCO:B0001391 ! SUV91_HUMAN relationship: location_of CCO:B0001450 ! SMC2_HUMAN relationship: location_of CCO:B0001481 ! HSP1_HUMAN relationship: location_of CCO:B0001482 ! PRM2_HUMAN relationship: location_of CCO:B0001526 ! H2AX_HUMAN relationship: location_of CCO:B0001753 ! TOP3A_HUMAN relationship: location_of CCO:B0001756 ! ATR_HUMAN relationship: location_of CCO:B0001886 ! Q5TCH6_HUMAN relationship: location_of CCO:B0001887 ! Q5TCH7_HUMAN relationship: location_of CCO:B0001977 ! SMC1B_HUMAN relationship: location_of CCO:B0002021 ! RAD50_HUMAN relationship: location_of CCO:B0002033 ! PINX1_HUMAN relationship: location_of CCO:B0002149 ! PRM3_HUMAN relationship: location_of CCO:B0002256 ! SPO11_HUMAN relationship: location_of CCO:B0005431 ! CENPB_HUMAN relationship: location_of CCO:B0005503 ! POTE1_HUMAN relationship: location_of CCO:B0005504 ! ACD_HUMAN relationship: location_of CCO:B0005587 ! TOP1_HUMAN relationship: location_of CCO:B0005682 ! CENPH_HUMAN relationship: location_of CCO:B0006198 ! CENPR_HUMAN relationship: location_of CCO:B0010723 ! AURKB_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0010825 ! BOREA_HUMAN-Phosphoserine219 relationship: location_of CCO:B0011143 ! CENPC_HUMAN-Phosphoserine520 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0011819 ! FACD2_HUMAN-Phosphoserine717 relationship: location_of CCO:B0011845 ! FANCI_HUMAN-Phosphoserine556 relationship: location_of CCO:B0011999 ! H11_HUMAN-N-acetylserine2 relationship: location_of CCO:B0012002 ! H14_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0012013 ! H2B1C_HUMAN-N6-acetyllysine13 relationship: location_of CCO:B0012048 ! H31_HUMAN-N6-acetyllysine37 relationship: location_of CCO:B0012088 ! H32_HUMAN-N6-acetyllysine57 relationship: location_of CCO:B0012117 ! H33_HUMAN-N6-methyllysine28 relationship: location_of CCO:B0012198 ! HMGB1_HUMAN-Phosphoserine35 relationship: location_of CCO:B0012223 ! HNRPD_HUMAN-Phosphoserine82 relationship: location_of CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0014023 ! SETB1_HUMAN-Phosphoserine1190 relationship: location_of CCO:B0014070 ! SMC1A_HUMAN-Phosphoserine951 relationship: location_of CCO:B0014074 ! SMC1B_HUMAN-Phosphoserine882 relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: location_of CCO:B0014085 ! SMC4_HUMAN-Phosphoserine1056 relationship: location_of CCO:B0014221 ! SSRP1_HUMAN-Phosphoserine444 relationship: location_of CCO:B0014328 ! TE2IP_HUMAN-Phosphoserine154 relationship: location_of CCO:B0014336 ! TERF2_HUMAN-Phosphoserine380 relationship: location_of CCO:B0015493 ! SUV42_HUMAN relationship: location_of CCO:B0015494 ! SUV41_HUMAN relationship: location_of CCO:B0017118 ! ING2_HUMAN relationship: location_of CCO:B0020552 ! RING2_HUMAN relationship: location_of CCO:B0021914 ! H2A2A_HUMAN relationship: location_of CCO:B0022073 ! SMC6_HUMAN relationship: location_of CCO:B0024782 ! TOP1M_HUMAN relationship: location_of CCO:B0032537 ! SP16H_HUMAN relationship: location_of CCO:B0035747 ! TB182_HUMAN-Phosphoserine1621 relationship: location_of CCO:B0039454 ! HILS1_HUMAN-Phosphothreonine130 relationship: location_of CCO:B0041139 ! H4_HUMAN-Phosphoserine2 relationship: location_of CCO:B0041249 ! HMGA2_HUMAN relationship: location_of CCO:B0043830 ! H1FNT_HUMAN relationship: location_of CCO:B0043831 ! H1FOO_HUMAN relationship: location_of CCO:B0048883 ! TAD2A_HUMAN relationship: location_of CCO:B0050276 ! HMGLX_HUMAN relationship: location_of CCO:B0050277 ! HMGB4_HUMAN relationship: location_of CCO:B0050279 ! HMGB3_HUMAN relationship: location_of CCO:B0050286 ! HG3BL_HUMAN relationship: location_of CCO:B0050294 ! HMGB2_HUMAN relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0054815 ! TOP3B_HUMAN relationship: location_of CCO:B0054943 ! STP1_HUMAN relationship: location_of CCO:B0057255 ! EST1A_HUMAN relationship: location_of CCO:B0057972 ! SETD7_HUMAN relationship: location_of CCO:B0058511 ! THAP7_HUMAN relationship: location_of CCO:B0059032 ! H2AW_HUMAN relationship: location_of CCO:B0064292 ! CENPU_HUMAN-Phosphoserine111 relationship: location_of CCO:B0064392 ! CLSPN_HUMAN-Phosphoserine83 relationship: location_of CCO:B0065574 ! AKP8L_HUMAN-Phosphoserine297 relationship: location_of CCO:B0066678 ! H12_HUMAN-Phosphoserine173 relationship: location_of CCO:B0066679 ! H1X_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066682 ! H2A1C_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066694 ! H2AY_HUMAN-N6-methyllysine18 relationship: location_of CCO:B0066708 ! H2B1B_HUMAN-N6-acetyllysine109 relationship: location_of CCO:B0066710 ! H2B1H_HUMAN-N6-acetyllysine6 relationship: location_of CCO:B0066732 ! H31T_HUMAN-Citrulline18 relationship: location_of CCO:B0066824 ! HMGA1_HUMAN-Phosphoserine36 relationship: location_of CCO:B0067520 ! LAP2A_HUMAN-Phosphoserine66 relationship: location_of CCO:B0070039 ! RIF1_HUMAN-Phosphoserine2176 relationship: location_of CCO:B0070386 ! SETD8_HUMAN-Phosphoserine100 relationship: location_of CCO:B0070768 ! SP100_HUMAN-Phosphoserine459 relationship: location_of CCO:B0071003 ! SUV92_HUMAN-Phosphoserine381 relationship: location_of CCO:B0071340 ! TERF1_HUMAN-Phosphoserine435 relationship: location_of CCO:B0071342 ! TERT_HUMAN-Phosphothreonine1113 relationship: location_of CCO:B0071407 ! TINF2_HUMAN-Phosphoserine295 [Term] id: CCO:C0000297 name: telomerase holoenzyme complex namespace: cellular_component def: "Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits." [PMID:11884619] subset: goslim_pir xref: GO:0005697 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0011519 ! DKC1_HUMAN-Phosphoserine513 relationship: location_of CCO:B0056049 ! TEBP_HUMAN relationship: location_of CCO:B0057255 ! EST1A_HUMAN relationship: location_of CCO:B0071342 ! TERT_HUMAN-Phosphothreonine1113 [Term] id: CCO:C0000298 name: polytene chromosome namespace: cellular_component def: "A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005700 is_a: CCO:C0000296 ! chromosome [Term] id: CCO:C0000299 name: polytene chromosome chromocenter namespace: cellular_component def: "A region at which the centric regions of polytene chromosomes are joined together." [GOC:bf, ISBN:0120649012] synonym: "polytene chromosome chromocentre" EXACT [] xref: GO:0005701 is_a: CCO:C0000730 ! chromocenter relationship: location_of CCO:B0037049 ! TRI66_HUMAN relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 relationship: part_of CCO:C0000298 ! polytene chromosome [Term] id: CCO:C0000300 name: polytene chromosome weak point namespace: cellular_component def: "A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization." [GOC:bf, ISBN:0120649012] synonym: "constriction" BROAD [] xref: GO:0005702 is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000298 ! polytene chromosome [Term] id: CCO:C0000301 name: polytene chromosome puff namespace: cellular_component def: "A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription." [GOC:bf, ISBN:0120649012] xref: GO:0005703 is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000298 ! polytene chromosome [Term] id: CCO:C0000302 name: polytene chromosome band namespace: cellular_component def: "A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band." [GOC:bf, PMID:11361342] xref: GO:0005704 is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000298 ! polytene chromosome [Term] id: CCO:C0000303 name: polytene chromosome interband namespace: cellular_component def: "A stretch of less tightly packed chromatin along the polytene chromosome, found between bands." [GOC:bf, PMID:11361342] xref: GO:0005705 is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000298 ! polytene chromosome [Term] id: CCO:C0000304 name: polytene chromosome ectopic fiber namespace: cellular_component def: "A thread-like connection joining two regions of ectopically paired polytene chromosomes." [GOC:bf, ISBN:0120649012] synonym: "polytene chromosome ectopic fibre" EXACT [] xref: GO:0005706 is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000298 ! polytene chromosome [Term] id: CCO:C0000305 name: chiasma namespace: cellular_component def: "A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005712 is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0000306 name: recombination nodule namespace: cellular_component def: "An electron dense structure that is associated with meiotic chromosomes." [GOC:elh] xref: GO:0005713 is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0000307 name: early recombination nodule namespace: cellular_component def: "An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I." [GOC:elh] xref: GO:0005714 is_a: CCO:C0000306 ! recombination nodule [Term] id: CCO:C0000308 name: late recombination nodule namespace: cellular_component def: "An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I." [GOC:elh] xref: GO:0005715 is_a: CCO:C0000306 ! recombination nodule [Term] id: CCO:C0000309 name: nuclear euchromatin namespace: cellular_component def: "The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005719 is_a: CCO:C0000117 ! nuclear chromatin is_a: CCO:C0000118 ! euchromatin relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 [Term] id: CCO:C0000310 name: nuclear heterochromatin namespace: cellular_component def: "A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005720 is_a: CCO:C0000117 ! nuclear chromatin is_a: CCO:C0000119 ! heterochromatin relationship: location_of CCO:B0005191 ! SATB1_HUMAN relationship: location_of CCO:B0010699 ! ATRX_HUMAN-Phosphoserine92 relationship: location_of CCO:B0010965 ! CBX1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0037714 ! DNM3L_HUMAN relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 relationship: location_of CCO:B0066252 ! FOXC1_HUMAN-Phosphoserine235 [Term] id: CCO:C0000312 name: beta-heterochromatin namespace: cellular_component def: "A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization." [PMID:11404334, PMID:8878678] xref: GO:0005722 is_a: CCO:C0002171 ! centromeric heterochromatin relationship: part_of CCO:C0000299 ! polytene chromosome chromocenter [Term] id: CCO:C0000313 name: alpha-heterochromatin namespace: cellular_component def: "A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization." [PMID:8878678] xref: GO:0005723 is_a: CCO:C0002171 ! centromeric heterochromatin relationship: part_of CCO:C0000299 ! polytene chromosome chromocenter [Term] id: CCO:C0000314 name: nuclear telomeric heterochromatin namespace: cellular_component def: "Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus." [GOC:ai] xref: GO:0005724 is_a: CCO:C0000310 ! nuclear heterochromatin is_a: CCO:C0001354 ! telomeric heterochromatin relationship: location_of CCO:B0035747 ! TB182_HUMAN-Phosphoserine1621 relationship: part_of CCO:C0000111 ! nuclear chromosome, telomeric region [Term] id: CCO:C0000315 name: intercalary heterochromatin namespace: cellular_component def: "Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes." [PMID:14579245] xref: GO:0005725 is_a: CCO:C0000310 ! nuclear heterochromatin [Term] id: CCO:C0000316 name: perichromatin fibrils namespace: cellular_component def: "Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts." [PMID:14731598] xref: GO:0005726 is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0059143 ! NUFP1_HUMAN relationship: part_of CCO:C0000117 ! nuclear chromatin [Term] id: CCO:C0000317 name: extrachromosomal circular DNA namespace: cellular_component def: "Circular DNA structures that are not part of a chromosome." [GOC:ai] subset: gosubset_prok xref: GO:0005727 is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0001971 ! extrachromosomal DNA [Term] id: CCO:C0000318 name: extrachromosomal rDNA circle namespace: cellular_component def: "Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats." [GOC:mah, PMID:12044934] synonym: "extrachromosomal ribosomal DNA circle" EXACT [] xref: GO:0005728 is_a: CCO:C0000317 ! extrachromosomal circular DNA [Term] id: CCO:C0000319 name: 2-micrometer circle DNA namespace: cellular_component def: "A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies." [PMID:12073320] xref: GO:0005729 is_a: CCO:C0000317 ! extrachromosomal circular DNA [Term] id: CCO:C0000320 name: nucleolus namespace: cellular_component def: "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast xref: GO:0005730 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001410 ! CCNT1_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0001676 ! NH2L1_HUMAN relationship: location_of CCO:B0001712 ! MDM2_HUMAN relationship: location_of CCO:B0001966 ! CD2A2_HUMAN relationship: location_of CCO:B0001984 ! NEK11_HUMAN relationship: location_of CCO:B0002018 ! SC65_HUMAN relationship: location_of CCO:B0002037 ! DDX11_HUMAN relationship: location_of CCO:B0002056 ! MPPH1_HUMAN relationship: location_of CCO:B0002103 ! GNL3_HUMAN relationship: location_of CCO:B0005348 ! EXOSX_HUMAN relationship: location_of CCO:B0005398 ! ELP1_HUMAN relationship: location_of CCO:B0005467 ! PARP1_HUMAN relationship: location_of CCO:B0005587 ! TOP1_HUMAN relationship: location_of CCO:B0005621 ! P80C_HUMAN relationship: location_of CCO:B0005744 ! RS19_HUMAN relationship: location_of CCO:B0005858 ! RL11_HUMAN relationship: location_of CCO:B0005877 ! PNMA1_HUMAN relationship: location_of CCO:B0005943 ! APTX_HUMAN relationship: location_of CCO:B0006137 ! DNJB9_HUMAN relationship: location_of CCO:B0006240 ! PNO1_HUMAN relationship: location_of CCO:B0010410 ! ABL1_HUMAN-Phosphoserine809 relationship: location_of CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0011509 ! DHX9_HUMAN-Phosphotyrosine1241 relationship: location_of CCO:B0011519 ! DKC1_HUMAN-Phosphoserine513 relationship: location_of CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 relationship: location_of CCO:B0011811 ! EXOS4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011812 ! EXOS5_HUMAN-Phosphoserine20 relationship: location_of CCO:B0011857 ! FBRL_HUMAN-Asymmetric dimethylarginine36 relationship: location_of CCO:B0011905 ! FXR1_HUMAN-Omega-N-methylated arginine445 relationship: location_of CCO:B0013206 ! NOL12_HUMAN-Phosphoserine140 relationship: location_of CCO:B0013217 ! NOL1_HUMAN-Phosphothreonine195 relationship: location_of CCO:B0013224 ! NOLC1_HUMAN-Phosphoserine87 relationship: location_of CCO:B0013270 ! NUCL_HUMAN-Phosphoserine34 relationship: location_of CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: location_of CCO:B0013943 ! RS7_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013960 ! SAS10_HUMAN-Phosphoserine368 relationship: location_of CCO:B0014198 ! SPTB2_HUMAN-Phosphothreonine2195 relationship: location_of CCO:B0014549 ! TSYL2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0014698 ! WRN_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0018024 ! ZPR1_HUMAN relationship: location_of CCO:B0019365 ! TAF5_HUMAN relationship: location_of CCO:B0020438 ! A6NNS1_HUMAN relationship: location_of CCO:B0022986 ! FGF18_HUMAN relationship: location_of CCO:B0025212 ! SBDS_HUMAN relationship: location_of CCO:B0026279 ! IF3EI_HUMAN relationship: location_of CCO:B0029592 ! RL36_HUMAN relationship: location_of CCO:B0029881 ! O15302_HUMAN relationship: location_of CCO:B0034696 ! DDX56_HUMAN-Phosphoserine126 relationship: location_of CCO:B0039600 ! PTBP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0039636 ! RPB1_HUMAN-Phosphotyrosine1923 relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0043507 ! XRN2_HUMAN-Phosphoserine501 relationship: location_of CCO:B0043604 ! DEDD_HUMAN relationship: location_of CCO:B0043605 ! DEDD2_HUMAN relationship: location_of CCO:B0048340 ! NPM_HUMAN-Phosphothreonine279 relationship: location_of CCO:B0048582 ! ELP2_HUMAN relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 relationship: location_of CCO:B0054315 ! O00366_HUMAN relationship: location_of CCO:B0054591 ! NOL3_HUMAN relationship: location_of CCO:B0055078 ! ZNF43_HUMAN relationship: location_of CCO:B0055725 ! ERCC6_HUMAN relationship: location_of CCO:B0055767 ! SUH_HUMAN relationship: location_of CCO:B0055855 ! ILF2_HUMAN relationship: location_of CCO:B0055990 ! S29A2_HUMAN relationship: location_of CCO:B0056172 ! IF16_HUMAN relationship: location_of CCO:B0056495 ! ZN506_HUMAN relationship: location_of CCO:B0057425 ! AL2S8_HUMAN relationship: location_of CCO:B0057925 ! DDX54_HUMAN relationship: location_of CCO:B0058214 ! ZN274_HUMAN relationship: location_of CCO:B0058634 ! REXO4_HUMAN relationship: location_of CCO:B0059143 ! NUFP1_HUMAN relationship: location_of CCO:B0062872 ! IMP3_HUMAN relationship: location_of CCO:B0062875 ! NOL4_HUMAN relationship: location_of CCO:B0063083 ! RL3_HUMAN relationship: location_of CCO:B0063091 ! RL35_HUMAN relationship: location_of CCO:B0063163 ! ZN330_HUMAN relationship: location_of CCO:B0064711 ! DDX24_HUMAN-Phosphoserine295 relationship: location_of CCO:B0065043 ! ELP3_HUMAN-Phosphotyrosine202 relationship: location_of CCO:B0065932 ! DDX21_HUMAN-Phosphoserine168 relationship: location_of CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 relationship: location_of CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0067798 ! LYAR_HUMAN-Phosphoserine258 relationship: location_of CCO:B0068027 ! MBB1A_HUMAN-Phosphothreonine1190 relationship: location_of CCO:B0068248 ! MO4L2_HUMAN-Phosphoserine71 relationship: location_of CCO:B0068778 ! NOL8_HUMAN-Phosphoserine845 relationship: location_of CCO:B0069236 ! PESC_HUMAN-Phosphotyrosine548 relationship: location_of CCO:B0070146 ! RPA34_HUMAN-Phosphotyrosine80 relationship: location_of CCO:B0070149 ! RPA49_HUMAN-Phosphoserine225 relationship: location_of CCO:B0071667 ! UBF1_HUMAN-Phosphoserine484 relationship: part_of CCO:C0001373 ! nuclear lumen [Term] id: CCO:C0000321 name: nucleolus organizer region namespace: cellular_component def: "A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed." [PMID:14504406] synonym: "NOR" EXACT [] synonym: "nucleolus organiser region" EXACT [] synonym: "nucleolus organizer complex" RELATED [] xref: GO:0005731 is_a: CCO:C0001064 ! nucleolar chromatin is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0063772 ! BAZ2A_HUMAN-Phosphothreonine521 [Term] id: CCO:C0000322 name: small nucleolar ribonucleoprotein complex namespace: cellular_component def: "A complex composed of RNA of the small nucleolar RNA (snoRNA) and protein, found in the nucleolus of a eukaryotic cell. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type." [GOC:krc, GOC:mah, ISBN:0879695897] subset: goslim_pir synonym: "small nucleolar ribonucleoprotein" EXACT [] synonym: "snoRNP" EXACT [] xref: GO:0005732 is_a: CCO:C0001019 ! ribonucleoprotein complex relationship: location_of CCO:B0005282 ! NOC4L_HUMAN relationship: location_of CCO:B0005996 ! WDR57_HUMAN relationship: location_of CCO:B0013158 ! NEP1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039769 ! UTP18_HUMAN-Phosphoserine210 relationship: location_of CCO:B0067447 ! KRR1_HUMAN-Phosphothreonine337 relationship: location_of CCO:B0071767 ! UTP20_HUMAN-Phosphoserine788 [Term] id: CCO:C0000323 name: DNA-directed RNA polymerase I complex namespace: cellular_component def: "RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template." [GOC:krc, GOC:mtg_sensu] synonym: "DNA-directed RNA polymerase I activity" RELATED [] xref: GO:0005736 is_a: CCO:C0001871 ! nucleolar part is_a: CCO:C0002015 ! nuclear DNA-directed RNA polymerase complex relationship: location_of CCO:B0013930 ! RPAC1_HUMAN-Phosphotyrosine33 relationship: location_of CCO:B0070146 ! RPA34_HUMAN-Phosphotyrosine80 [Term] id: CCO:C0000324 name: cytoplasm namespace: cellular_component def: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0005737 is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001346 ! CDC7_HUMAN relationship: location_of CCO:B0001353 ! PPP6_HUMAN relationship: location_of CCO:B0001355 ! CDKA1_HUMAN relationship: location_of CCO:B0001357 ! ANM5_HUMAN relationship: location_of CCO:B0001367 ! AXN1_HUMAN relationship: location_of CCO:B0001370 ! FANCG_HUMAN relationship: location_of CCO:B0001371 ! LX15B_HUMAN relationship: location_of CCO:B0001376 ! HDAC3_HUMAN relationship: location_of CCO:B0001382 ! SEPT4_HUMAN relationship: location_of CCO:B0001384 ! SIAH2_HUMAN relationship: location_of CCO:B0001397 ! ACTN4_HUMAN relationship: location_of CCO:B0001398 ! TRIA1_HUMAN relationship: location_of CCO:B0001401 ! GAS2_HUMAN relationship: location_of CCO:B0001409 ! DBC1_HUMAN relationship: location_of CCO:B0001416 ! TRI13_HUMAN relationship: location_of CCO:B0001417 ! GAS7_HUMAN relationship: location_of CCO:B0001419 ! HUS1_HUMAN relationship: location_of CCO:B0001426 ! CC45L_HUMAN relationship: location_of CCO:B0001427 ! KTNA1_HUMAN relationship: location_of CCO:B0001435 ! CD123_HUMAN relationship: location_of CCO:B0001440 ! DCTN3_HUMAN relationship: location_of CCO:B0001442 ! RECQ4_HUMAN relationship: location_of CCO:B0001443 ! BPAEA_HUMAN relationship: location_of CCO:B0001450 ! SMC2_HUMAN relationship: location_of CCO:B0001457 ! PTTG1_HUMAN relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0001490 ! LCK_HUMAN relationship: location_of CCO:B0001494 ! S10A6_HUMAN relationship: location_of CCO:B0001519 ! CCNB1_HUMAN relationship: location_of CCO:B0001523 ! PGDH_HUMAN relationship: location_of CCO:B0001524 ! NDKA_HUMAN relationship: location_of CCO:B0001538 ! CCNA2_HUMAN relationship: location_of CCO:B0001546 ! NDKB_HUMAN relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0001565 ! MK01_HUMAN relationship: location_of CCO:B0001569 ! SHC1_HUMAN relationship: location_of CCO:B0001574 ! CCND3_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0001594 ! DDIT3_HUMAN relationship: location_of CCO:B0001595 ! AHR_HUMAN relationship: location_of CCO:B0001599 ! CDN1A_HUMAN relationship: location_of CCO:B0001600 ! VHL_HUMAN relationship: location_of CCO:B0001608 ! STAT1_HUMAN relationship: location_of CCO:B0001611 ! FRAP_HUMAN relationship: location_of CCO:B0001615 ! CD2A1_HUMAN relationship: location_of CCO:B0001616 ! CDN2B_HUMAN relationship: location_of CCO:B0001617 ! CDN2C_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001636 ! FHIT_HUMAN relationship: location_of CCO:B0001648 ! TCPD_HUMAN relationship: location_of CCO:B0001649 ! BRCA2_HUMAN relationship: location_of CCO:B0001662 ! PPP5_HUMAN relationship: location_of CCO:B0001671 ! BCAT1_HUMAN relationship: location_of CCO:B0001675 ! CDN2D_HUMAN relationship: location_of CCO:B0001681 ! SESN2_HUMAN relationship: location_of CCO:B0001684 ! MLF1_HUMAN relationship: location_of CCO:B0001688 ! PP1A_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0001708 ! CDK6_HUMAN relationship: location_of CCO:B0001712 ! MDM2_HUMAN relationship: location_of CCO:B0001723 ! BAX_HUMAN relationship: location_of CCO:B0001737 ! STRN3_HUMAN relationship: location_of CCO:B0001752 ! UB2V1_HUMAN relationship: location_of CCO:B0001754 ! TBB3_HUMAN relationship: location_of CCO:B0001758 ! ULA1_HUMAN relationship: location_of CCO:B0001769 ! TBB2A_HUMAN relationship: location_of CCO:B0001774 ! TOB2_HUMAN relationship: location_of CCO:B0001778 ! BTG3_HUMAN relationship: location_of CCO:B0001780 ! DYHC1_HUMAN relationship: location_of CCO:B0001789 ! KANK1_HUMAN relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0001804 ! E2F5_HUMAN relationship: location_of CCO:B0001813 ! UB2V2_HUMAN relationship: location_of CCO:B0001831 ! Q3LRW5_HUMAN relationship: location_of CCO:B0001838 ! PKHO1_HUMAN relationship: location_of CCO:B0001842 ! BMCC1_HUMAN relationship: location_of CCO:B0001899 ! DAB2P_HUMAN relationship: location_of CCO:B0001909 ! RINT1_HUMAN relationship: location_of CCO:B0001913 ! L2GL2_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0001946 ! SIAH1_HUMAN relationship: location_of CCO:B0001949 ! PARC_HUMAN relationship: location_of CCO:B0001950 ! CCAR1_HUMAN relationship: location_of CCO:B0001954 ! XRN1_HUMAN relationship: location_of CCO:B0001972 ! BOLL_HUMAN relationship: location_of CCO:B0001976 ! RCBT1_HUMAN relationship: location_of CCO:B0001980 ! DP13B_HUMAN relationship: location_of CCO:B0001981 ! FLCN_HUMAN relationship: location_of CCO:B0001985 ! GA2L2_HUMAN relationship: location_of CCO:B0001988 ! UHMK1_HUMAN relationship: location_of CCO:B0001990 ! PIWL2_HUMAN relationship: location_of CCO:B0002002 ! HDAC7_HUMAN relationship: location_of CCO:B0002008 ! RASF5_HUMAN relationship: location_of CCO:B0002012 ! RSPH1_HUMAN relationship: location_of CCO:B0002023 ! ARHG1_HUMAN relationship: location_of CCO:B0002026 ! NAT6_HUMAN relationship: location_of CCO:B0002029 ! TP4A1_HUMAN relationship: location_of CCO:B0002034 ! CCDC5_HUMAN relationship: location_of CCO:B0002039 ! SIPA1_HUMAN relationship: location_of CCO:B0002047 ! LMLN_HUMAN relationship: location_of CCO:B0002056 ! MPPH1_HUMAN relationship: location_of CCO:B0002059 ! LAP2_HUMAN relationship: location_of CCO:B0002060 ! NEB2_HUMAN relationship: location_of CCO:B0002065 ! CDC5L_HUMAN relationship: location_of CCO:B0002070 ! ZWIA_HUMAN relationship: location_of CCO:B0002071 ! MPH6_HUMAN relationship: location_of CCO:B0002075 ! NECD_HUMAN relationship: location_of CCO:B0002086 ! BARD1_HUMAN relationship: location_of CCO:B0002089 ! TCPH_HUMAN relationship: location_of CCO:B0002094 ! LZTS2_HUMAN relationship: location_of CCO:B0002099 ! CP250_HUMAN relationship: location_of CCO:B0002100 ! KTNB1_HUMAN relationship: location_of CCO:B0002104 ! TIPIN_HUMAN relationship: location_of CCO:B0002112 ! PAR6G_HUMAN relationship: location_of CCO:B0002113 ! PAR6B_HUMAN relationship: location_of CCO:B0002114 ! Q9BYG9_HUMAN relationship: location_of CCO:B0002117 ! DPH1_HUMAN relationship: location_of CCO:B0002119 ! STRAB_HUMAN relationship: location_of CCO:B0002123 ! ILKAP_HUMAN relationship: location_of CCO:B0002133 ! TXNIP_HUMAN relationship: location_of CCO:B0002145 ! NEK6_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0002150 ! PAR6A_HUMAN relationship: location_of CCO:B0002153 ! CYLD_HUMAN relationship: location_of CCO:B0002155 ! ANLN_HUMAN relationship: location_of CCO:B0002156 ! BIN3_HUMAN relationship: location_of CCO:B0002162 ! RASF1_HUMAN relationship: location_of CCO:B0002165 ! KIF15_HUMAN relationship: location_of CCO:B0002177 ! APC11_HUMAN relationship: location_of CCO:B0002180 ! GTSE1_HUMAN relationship: location_of CCO:B0002181 ! WWOX_HUMAN relationship: location_of CCO:B0002197 ! DMBT1_HUMAN relationship: location_of CCO:B0002198 ! SEPT3_HUMAN relationship: location_of CCO:B0002206 ! HERC5_HUMAN relationship: location_of CCO:B0002221 ! FBX5_HUMAN relationship: location_of CCO:B0002228 ! ASC_HUMAN relationship: location_of CCO:B0002238 ! MARE3_HUMAN relationship: location_of CCO:B0002247 ! DLEC1_HUMAN relationship: location_of CCO:B0002248 ! LZTS1_HUMAN relationship: location_of CCO:B0002249 ! RUVB1_HUMAN relationship: location_of CCO:B0002251 ! ATF5_HUMAN relationship: location_of CCO:B0002253 ! STA13_HUMAN relationship: location_of CCO:B0002254 ! RBGP1_HUMAN relationship: location_of CCO:B0002263 ! EID1_HUMAN relationship: location_of CCO:B0002265 ! USH1C_HUMAN relationship: location_of CCO:B0005170 ! TRAF2_HUMAN relationship: location_of CCO:B0005175 ! BAD_HUMAN relationship: location_of CCO:B0005181 ! UBQL1_HUMAN relationship: location_of CCO:B0005183 ! PLDN_HUMAN relationship: location_of CCO:B0005211 ! DVL2_HUMAN relationship: location_of CCO:B0005212 ! MAGAB_HUMAN relationship: location_of CCO:B0005216 ! RIPK2_HUMAN relationship: location_of CCO:B0005224 ! PDLI7_HUMAN relationship: location_of CCO:B0005232 ! MDFI_HUMAN relationship: location_of CCO:B0005233 ! PSA1_HUMAN relationship: location_of CCO:B0005250 ! MYOZ2_HUMAN relationship: location_of CCO:B0005253 ! TCPG_HUMAN relationship: location_of CCO:B0005260 ! NIF3L_HUMAN relationship: location_of CCO:B0005265 ! DYRK2_HUMAN relationship: location_of CCO:B0005270 ! CHM4B_HUMAN relationship: location_of CCO:B0005273 ! TOLIP_HUMAN relationship: location_of CCO:B0005281 ! M1IP1_HUMAN relationship: location_of CCO:B0005283 ! TS101_HUMAN relationship: location_of CCO:B0005300 ! TAK1L_HUMAN relationship: location_of CCO:B0005305 ! LNX1_HUMAN relationship: location_of CCO:B0005322 ! SMAD4_HUMAN relationship: location_of CCO:B0005323 ! FANCA_HUMAN relationship: location_of CCO:B0005332 ! FBX11_HUMAN relationship: location_of CCO:B0005338 ! CDC42_HUMAN relationship: location_of CCO:B0005341 ! HDA10_HUMAN relationship: location_of CCO:B0005348 ! EXOSX_HUMAN relationship: location_of CCO:B0005364 ! RUVB2_HUMAN relationship: location_of CCO:B0005367 ! ARP6_HUMAN relationship: location_of CCO:B0005375 ! STK36_HUMAN relationship: location_of CCO:B0005387 ! TELT_HUMAN relationship: location_of CCO:B0005393 ! FEZ1_HUMAN relationship: location_of CCO:B0005398 ! ELP1_HUMAN relationship: location_of CCO:B0005405 ! GASP2_HUMAN relationship: location_of CCO:B0005409 ! IMB1_HUMAN relationship: location_of CCO:B0005422 ! BID_HUMAN relationship: location_of CCO:B0005426 ! CENPJ_HUMAN relationship: location_of CCO:B0005433 ! DCP2_HUMAN relationship: location_of CCO:B0005434 ! REN3B_HUMAN relationship: location_of CCO:B0005435 ! RENT2_HUMAN relationship: location_of CCO:B0005436 ! REN3A_HUMAN relationship: location_of CCO:B0005443 ! PARK7_HUMAN relationship: location_of CCO:B0005468 ! MED28_HUMAN relationship: location_of CCO:B0005471 ! BRAP_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005490 ! 1433F_HUMAN relationship: location_of CCO:B0005496 ! TDRD7_HUMAN relationship: location_of CCO:B0005512 ! AKT1_HUMAN relationship: location_of CCO:B0005514 ! CEBPB_HUMAN relationship: location_of CCO:B0005518 ! 2A5E_HUMAN relationship: location_of CCO:B0005519 ! SET_HUMAN relationship: location_of CCO:B0005520 ! M3K8_HUMAN relationship: location_of CCO:B0005528 ! M3K14_HUMAN relationship: location_of CCO:B0005536 ! TRAF6_HUMAN relationship: location_of CCO:B0005541 ! UCHL1_HUMAN relationship: location_of CCO:B0005543 ! AVR2A_HUMAN relationship: location_of CCO:B0005556 ! EXOS8_HUMAN relationship: location_of CCO:B0005562 ! DLRB1_HUMAN relationship: location_of CCO:B0005567 ! LSM6_HUMAN relationship: location_of CCO:B0005591 ! DISC1_HUMAN relationship: location_of CCO:B0005593 ! CRNL1_HUMAN relationship: location_of CCO:B0005599 ! KINH_HUMAN relationship: location_of CCO:B0005602 ! LIPA2_HUMAN relationship: location_of CCO:B0005619 ! UBQL4_HUMAN relationship: location_of CCO:B0005633 ! FBW1A_HUMAN relationship: location_of CCO:B0005642 ! ACTN2_HUMAN relationship: location_of CCO:B0005645 ! OBSCN_HUMAN relationship: location_of CCO:B0005650 ! SHOC2_HUMAN relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0005655 ! FKB1A_HUMAN relationship: location_of CCO:B0005661 ! IPO7_HUMAN relationship: location_of CCO:B0005662 ! XPO2_HUMAN relationship: location_of CCO:B0005663 ! TNPO1_HUMAN relationship: location_of CCO:B0005664 ! XPOT_HUMAN relationship: location_of CCO:B0005669 ! ELMO1_HUMAN relationship: location_of CCO:B0005671 ! BIRC2_HUMAN relationship: location_of CCO:B0005672 ! TRADD_HUMAN relationship: location_of CCO:B0005675 ! HIPK1_HUMAN relationship: location_of CCO:B0005691 ! SMU1_HUMAN relationship: location_of CCO:B0005692 ! CAC1C_HUMAN relationship: location_of CCO:B0005695 ! NMI_HUMAN relationship: location_of CCO:B0005697 ! IMA5_HUMAN relationship: location_of CCO:B0005706 ! M4K2_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0005713 ! ANM1_HUMAN relationship: location_of CCO:B0005739 ! GBLP_HUMAN relationship: location_of CCO:B0005753 ! SYFB_HUMAN relationship: location_of CCO:B0005767 ! RS12_HUMAN relationship: location_of CCO:B0005776 ! RSSA_HUMAN relationship: location_of CCO:B0005779 ! ENOA_HUMAN relationship: location_of CCO:B0005790 ! MED15_HUMAN relationship: location_of CCO:B0005795 ! MED22_HUMAN relationship: location_of CCO:B0005802 ! DOCK1_HUMAN relationship: location_of CCO:B0005810 ! ACTA_HUMAN relationship: location_of CCO:B0005816 ! ATX10_HUMAN relationship: location_of CCO:B0005828 ! GRP75_HUMAN relationship: location_of CCO:B0005830 ! FHL2_HUMAN relationship: location_of CCO:B0005837 ! PAXI_HUMAN relationship: location_of CCO:B0005850 ! GLI3_HUMAN relationship: location_of CCO:B0005860 ! RL8_HUMAN relationship: location_of CCO:B0005869 ! UBE2N_HUMAN relationship: location_of CCO:B0005876 ! CAB39_HUMAN relationship: location_of CCO:B0005877 ! PNMA1_HUMAN relationship: location_of CCO:B0005886 ! DAZ1_HUMAN relationship: location_of CCO:B0005932 ! UBL5_HUMAN relationship: location_of CCO:B0005933 ! BTBD2_HUMAN relationship: location_of CCO:B0005941 ! FBW1B_HUMAN relationship: location_of CCO:B0005942 ! WASL_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0005948 ! ACTN1_HUMAN relationship: location_of CCO:B0005950 ! BECN1_HUMAN relationship: location_of CCO:B0005951 ! BRE_HUMAN relationship: location_of CCO:B0005954 ! DTNA_HUMAN relationship: location_of CCO:B0005960 ! GRIP2_HUMAN relationship: location_of CCO:B0005962 ! HECW1_HUMAN relationship: location_of CCO:B0005969 ! TRIM1_HUMAN relationship: location_of CCO:B0005977 ! PDZD4_HUMAN relationship: location_of CCO:B0005980 ! ZN363_HUMAN relationship: location_of CCO:B0005981 ! TRI27_HUMAN relationship: location_of CCO:B0005992 ! TRAF1_HUMAN relationship: location_of CCO:B0006001 ! RFWD2_HUMAN relationship: location_of CCO:B0006002 ! TRIB1_HUMAN relationship: location_of CCO:B0006010 ! TNR8_HUMAN relationship: location_of CCO:B0006012 ! 4ET_HUMAN relationship: location_of CCO:B0006020 ! BC11A_HUMAN relationship: location_of CCO:B0006040 ! OLA1_HUMAN relationship: location_of CCO:B0006060 ! DAPK3_HUMAN relationship: location_of CCO:B0006067 ! NTF2_HUMAN relationship: location_of CCO:B0006076 ! CNBP1_HUMAN relationship: location_of CCO:B0006083 ! SBP1_HUMAN relationship: location_of CCO:B0006089 ! COX17_HUMAN relationship: location_of CCO:B0006098 ! PA1B3_HUMAN relationship: location_of CCO:B0006100 ! RPB3_HUMAN relationship: location_of CCO:B0006102 ! IPYR_HUMAN relationship: location_of CCO:B0006107 ! SAT1_HUMAN relationship: location_of CCO:B0006108 ! SPB9_HUMAN relationship: location_of CCO:B0006112 ! ST1E1_HUMAN relationship: location_of CCO:B0006114 ! KITH_HUMAN relationship: location_of CCO:B0006117 ! AK1C3_HUMAN relationship: location_of CCO:B0006125 ! CAPZB_HUMAN relationship: location_of CCO:B0006133 ! CSN6_HUMAN relationship: location_of CCO:B0006135 ! UBR1_HUMAN relationship: location_of CCO:B0006136 ! DJB11_HUMAN relationship: location_of CCO:B0006137 ! DNJB9_HUMAN relationship: location_of CCO:B0006143 ! GPDA_HUMAN relationship: location_of CCO:B0006144 ! GSTM4_HUMAN relationship: location_of CCO:B0006145 ! GSTP1_HUMAN relationship: location_of CCO:B0006149 ! ID2_HUMAN relationship: location_of CCO:B0006155 ! PROF2_HUMAN relationship: location_of CCO:B0006166 ! KIF5A_HUMAN relationship: location_of CCO:B0006169 ! WDR33_HUMAN relationship: location_of CCO:B0006172 ! ARPC3_HUMAN relationship: location_of CCO:B0006179 ! APLP1_HUMAN relationship: location_of CCO:B0006184 ! GLYC_HUMAN relationship: location_of CCO:B0006187 ! SH3G3_HUMAN relationship: location_of CCO:B0006189 ! ETHE1_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006198 ! CENPR_HUMAN relationship: location_of CCO:B0006209 ! MYCBP_HUMAN relationship: location_of CCO:B0006215 ! PSME1_HUMAN relationship: location_of CCO:B0006216 ! PKHA4_HUMAN relationship: location_of CCO:B0006219 ! PSB10_HUMAN relationship: location_of CCO:B0006224 ! RECQ5_HUMAN relationship: location_of CCO:B0006226 ! DYL1_HUMAN relationship: location_of CCO:B0006227 ! PRKN2_HUMAN relationship: location_of CCO:B0006230 ! RNF10_HUMAN relationship: location_of CCO:B0006232 ! RIR1_HUMAN relationship: location_of CCO:B0006255 ! ABC3G_HUMAN relationship: location_of CCO:B0006264 ! CSN7A_HUMAN relationship: location_of CCO:B0006270 ! ENOG_HUMAN relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0006282 ! LYPA2_HUMAN relationship: location_of CCO:B0006291 ! PA1B2_HUMAN relationship: location_of CCO:B0006294 ! PTOV1_HUMAN relationship: location_of CCO:B0006299 ! VPS29_HUMAN relationship: location_of CCO:B0006305 ! UBP4_HUMAN relationship: location_of CCO:B0006310 ! SH3G1_HUMAN relationship: location_of CCO:B0006322 ! CYTA_HUMAN relationship: location_of CCO:B0006326 ! PEF1_HUMAN relationship: location_of CCO:B0006333 ! TTLL5_HUMAN relationship: location_of CCO:B0006334 ! AMRP_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: location_of CCO:B0006344 ! NUD10_HUMAN relationship: location_of CCO:B0006347 ! XPP1_HUMAN relationship: location_of CCO:B0006349 ! SCFD1_HUMAN relationship: location_of CCO:B0010365 ! 1433B_HUMAN-Phosphoserine186 relationship: location_of CCO:B0010366 ! 1433E_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010371 ! 1433S_HUMAN-Phosphoserine216 relationship: location_of CCO:B0010373 ! 1433Z_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010410 ! ABL1_HUMAN-Phosphoserine809 relationship: location_of CCO:B0010419 ! ABL2_HUMAN-Phosphothreonine440 relationship: location_of CCO:B0010436 ! ACSA_HUMAN-Phosphoserine267 relationship: location_of CCO:B0010440 ! ACTB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010454 ! ADA17_HUMAN-Phosphoserine382 relationship: location_of CCO:B0010467 ! AF1L2_HUMAN-Phosphothreonine345 relationship: location_of CCO:B0010481 ! AIP_HUMAN-Phosphotyrosine248 relationship: location_of CCO:B0010486 ! AKAP9_HUMAN-Phosphoserine3869 relationship: location_of CCO:B0010497 ! AKT3_HUMAN-Phosphothreonine305 relationship: location_of CCO:B0010509 ! AN32A_HUMAN-Phosphoserine158 relationship: location_of CCO:B0010562 ! ANXA6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0010567 ! APC_HUMAN-Phosphoserine1038 relationship: location_of CCO:B0010588 ! ARD1A_HUMAN-Phosphoserine186 relationship: location_of CCO:B0010590 ! ARFG1_HUMAN-Phosphothreonine189 relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010604 ! ARP8_HUMAN-Phosphoserine132 relationship: location_of CCO:B0010623 ! ASPM_HUMAN-Phosphoserine605 relationship: location_of CCO:B0010629 ! ASPP1_HUMAN-Phosphoserine335 relationship: location_of CCO:B0010660 ! ATN1_HUMAN-Phosphoserine34 relationship: location_of CCO:B0010721 ! ATX7_HUMAN-Phosphothreonine854 relationship: location_of CCO:B0010732 ! BAT2_HUMAN-Phosphoserine350 relationship: location_of CCO:B0010760 ! BCAR1_HUMAN-Phosphotyrosine362 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0010790 ! BEGIN_HUMAN-Phosphoserine502 relationship: location_of CCO:B0010794 ! BIN1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0010825 ! BOREA_HUMAN-Phosphoserine219 relationship: location_of CCO:B0010865 ! BRD7_HUMAN-Phosphoserine279 relationship: location_of CCO:B0010867 ! BRSK1_HUMAN-Phosphoserine209 relationship: location_of CCO:B0010872 ! CABL1_HUMAN-Phosphoserine313 relationship: location_of CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: location_of CCO:B0010903 ! CAF1B_HUMAN-Phosphothreonine495 relationship: location_of CCO:B0010912 ! CALM_HUMAN-N6,N6,N6-trimethyllysine116 relationship: location_of CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: location_of CCO:B0010939 ! CBLB_HUMAN-Phosphoserine480 relationship: location_of CCO:B0010952 ! CBL_HUMAN-Phosphoserine900 relationship: location_of CCO:B0011022 ! CD2L1_HUMAN-Phosphothreonine595 relationship: location_of CCO:B0011030 ! CD2L2_HUMAN-Phosphothreonine736 relationship: location_of CCO:B0011054 ! CDC16_HUMAN-Phosphoserine560 relationship: location_of CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: location_of CCO:B0011082 ! CDC37_HUMAN-Phosphotyrosine298 relationship: location_of CCO:B0011087 ! CDC6_HUMAN-Phosphothreonine166 relationship: location_of CCO:B0011105 ! CDK2_HUMAN-Phosphotyrosine19 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0011126 ! CDN1B_HUMAN-Phosphoserine10 relationship: location_of CCO:B0011131 ! CELF1_HUMAN-Phosphoserine302 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0011197 ! CH60_HUMAN-Phosphoserine70 relationship: location_of CCO:B0011213 ! CHK1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0011239 ! CKAP2_HUMAN-Phosphoserine602 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0011292 ! CND1_HUMAN-Phosphoserine1376 relationship: location_of CCO:B0011307 ! CND3_HUMAN-Phosphoserine674 relationship: location_of CCO:B0011338 ! CPNS1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011355 ! CSK_HUMAN-Phosphotyrosine304 relationship: location_of CCO:B0011360 ! CSN1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0011362 ! CSN5_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0011392 ! CTND1_HUMAN-Phosphoserine269 relationship: location_of CCO:B0011406 ! CTRO_HUMAN-Phosphoserine440 relationship: location_of CCO:B0011452 ! DCTN1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0011456 ! DDB1_HUMAN-Phosphoserine766 relationship: location_of CCO:B0011473 ! DDX3X_HUMAN-Phosphoserine74 relationship: location_of CCO:B0011486 ! DDX6_HUMAN-Phosphothreonine36 relationship: location_of CCO:B0011509 ! DHX9_HUMAN-Phosphotyrosine1241 relationship: location_of CCO:B0011527 ! DLG5_HUMAN-Phosphothreonine1011 relationship: location_of CCO:B0011552 ! DNJB6_HUMAN-Phosphoserine277 relationship: location_of CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: location_of CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: location_of CCO:B0011610 ! E2AK1_HUMAN-Phosphothreonine488 relationship: location_of CCO:B0011620 ! E2F1_HUMAN-Phosphoserine375 relationship: location_of CCO:B0011630 ! EDC4_HUMAN-Phosphoserine879 relationship: location_of CCO:B0011635 ! EF1A1_HUMAN-N6,N6,N6-trimethyllysine36 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0011697 ! EP15_HUMAN-Phosphoserine324 relationship: location_of CCO:B0011767 ! ESPL1_HUMAN-Phosphoserine1508 relationship: location_of CCO:B0011798 ! EWS_HUMAN-Asymmetric dimethylarginine589 relationship: location_of CCO:B0011809 ! EXOC8_HUMAN-Phosphoserine19 relationship: location_of CCO:B0011810 ! EXOS3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011811 ! EXOS4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011812 ! EXOS5_HUMAN-Phosphoserine20 relationship: location_of CCO:B0011839 ! FAK2_HUMAN-Phosphotyrosine881 relationship: location_of CCO:B0011886 ! FNBP1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0011896 ! FRK_HUMAN-Phosphotyrosine387 relationship: location_of CCO:B0011899 ! FRMD6_HUMAN-Phosphoserine525 relationship: location_of CCO:B0011905 ! FXR1_HUMAN-Omega-N-methylated arginine445 relationship: location_of CCO:B0011912 ! FZR_HUMAN-Phosphoserine151 relationship: location_of CCO:B0011913 ! G3P_HUMAN-Phosphotyrosine42 relationship: location_of CCO:B0011920 ! GAK_HUMAN-Phosphoserine829 relationship: location_of CCO:B0011932 ! GIT1_HUMAN-Phosphoserine134 relationship: location_of CCO:B0012158 ! HDAC1_HUMAN-Phosphoserine423 relationship: location_of CCO:B0012159 ! HDAC2_HUMAN-Phosphoserine394 relationship: location_of CCO:B0012164 ! HDAC4_HUMAN-Phosphoserine467 relationship: location_of CCO:B0012166 ! HDAC5_HUMAN-Phosphoserine259 relationship: location_of CCO:B0012168 ! HDAC6_HUMAN-Phosphoserine22 relationship: location_of CCO:B0012174 ! HDAC9_HUMAN-Phosphoserine451 relationship: location_of CCO:B0012175 ! HD_HUMAN-Phosphoserine421 relationship: location_of CCO:B0012178 ! HECAM_HUMAN-Phosphoserine318 relationship: location_of CCO:B0012180 ! HEXI1_HUMAN-Phosphoserine97 relationship: location_of CCO:B0012186 ! HGS_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0012195 ! HIF1A_HUMAN-3-hydroxyasparagine803 relationship: location_of CCO:B0012250 ! HNRPK_HUMAN-Omega-N-methylated arginine296 relationship: location_of CCO:B0012253 ! HOOK1_HUMAN-Phosphoserine235 relationship: location_of CCO:B0012271 ! HS90B_HUMAN-Phosphothreonine297 relationship: location_of CCO:B0012274 ! HSP71_HUMAN-Phosphotyrosine611 relationship: location_of CCO:B0012280 ! HSPB1_HUMAN-Phosphoserine26 relationship: location_of CCO:B0012286 ! HTAI2_HUMAN-Phosphoserine45 relationship: location_of CCO:B0012288 ! HUWE1_HUMAN-Phosphoserine1907 relationship: location_of CCO:B0012347 ! IKKA_HUMAN-Phosphothreonine23 relationship: location_of CCO:B0012361 ! IKKB_HUMAN-Phosphoserine733 relationship: location_of CCO:B0012364 ! IKKE_HUMAN-Phosphoserine172 relationship: location_of CCO:B0012377 ! IMA2_HUMAN-Phosphoserine490 relationship: location_of CCO:B0012378 ! IMA3_HUMAN-Phosphoserine60 relationship: location_of CCO:B0012432 ! ITSN2_HUMAN-Phosphotyrosine967 relationship: location_of CCO:B0012444 ! JIP3_HUMAN-Phosphoserine365 relationship: location_of CCO:B0012459 ! K1C17_HUMAN-Phosphoserine319 relationship: location_of CCO:B0012464 ! K1C18_HUMAN-Phosphoserine15 relationship: location_of CCO:B0012485 ! K2C7_HUMAN-Phosphotyrosine375 relationship: location_of CCO:B0012493 ! K2C8_HUMAN-Phosphoserine27 relationship: location_of CCO:B0012512 ! KC1E_HUMAN-Phosphoserine363 relationship: location_of CCO:B0012613 ! KNTC1_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0012627 ! KPCA_HUMAN-Phosphoserine657 relationship: location_of CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0012636 ! KPCZ_HUMAN-Phosphothreonine560 relationship: location_of CCO:B0012651 ! KU70_HUMAN-Phosphoserine51 relationship: location_of CCO:B0012698 ! LIMK1_HUMAN-Phosphoserine298 relationship: location_of CCO:B0012747 ! MACF1_HUMAN-Phosphoserine1860 relationship: location_of CCO:B0012761 ! MAP9_HUMAN-Phosphoserine132 relationship: location_of CCO:B0012762 ! MAPK5_HUMAN-Phosphothreonine182 relationship: location_of CCO:B0012763 ! MARE1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012780 ! MATK_HUMAN-Phosphoserine501 relationship: location_of CCO:B0012841 ! MCRS1_HUMAN-Phosphoserine108 relationship: location_of CCO:B0012846 ! MD2BP_HUMAN-Phosphoserine29 relationship: location_of CCO:B0012956 ! MK12_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0012966 ! MLTK_HUMAN-Phosphoserine635 relationship: location_of CCO:B0012994 ! MPP8_HUMAN-Phosphoserine164 relationship: location_of CCO:B0013035 ! MTMR6_HUMAN-Phosphoserine561 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013088 ! NACA_HUMAN-Phosphothreonine161 relationship: location_of CCO:B0013102 ! NASP_HUMAN-Phosphoserine726 relationship: location_of CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: location_of CCO:B0013138 ! NDEL1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0013145 ! NEK1_HUMAN-Phosphothreonine162 relationship: location_of CCO:B0013156 ! NEK9_HUMAN-Phosphoserine869 relationship: location_of CCO:B0013164 ! NFKB2_HUMAN-Phosphoserine713 relationship: location_of CCO:B0013200 ! NOG1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013224 ! NOLC1_HUMAN-Phosphoserine87 relationship: location_of CCO:B0013288 ! NUDC_HUMAN-Phosphoserine274 relationship: location_of CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013366 ! PA2G4_HUMAN-Phosphoserine2 relationship: location_of CCO:B0013372 ! PABP1_HUMAN-Omega-N-methylated arginine493 relationship: location_of CCO:B0013375 ! PAK1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0013399 ! PARN_HUMAN-Phosphoserine557 relationship: location_of CCO:B0013450 ! PDCD4_HUMAN-Phosphoserine76 relationship: location_of CCO:B0013463 ! PDLI1_HUMAN-Phosphotyrosine321 relationship: location_of CCO:B0013478 ! PDPK1_HUMAN-Phosphoserine241 relationship: location_of CCO:B0013493 ! PEX19_HUMAN-Phosphoserine184 relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0013549 ! PKN1_HUMAN-Phosphothreonine774 relationship: location_of CCO:B0013563 ! PLCB1_HUMAN-N6-acetyllysine976 relationship: location_of CCO:B0013567 ! PLCG1_HUMAN-Phosphotyrosine1253 relationship: location_of CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: location_of CCO:B0013594 ! PP1B_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013601 ! PPIA_HUMAN-Phosphoserine21 relationship: location_of CCO:B0013606 ! PPM1G_HUMAN-Phosphoserine527 relationship: location_of CCO:B0013610 ! PRC1_HUMAN-Phosphothreonine481 relationship: location_of CCO:B0013613 ! PROF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013617 ! PRS4_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0013620 ! PSA3_HUMAN-Phosphotyrosine161 relationship: location_of CCO:B0013641 ! PTEN_HUMAN-Phosphoserine370 relationship: location_of CCO:B0013674 ! RAD9A_HUMAN-Phosphoserine328 relationship: location_of CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013714 ! RASA1_HUMAN-Phosphotyrosine615 relationship: location_of CCO:B0013797 ! RBM8A_HUMAN-Phosphoserine166 relationship: location_of CCO:B0013809 ! RCC1_HUMAN-Phosphothreonine411 relationship: location_of CCO:B0013820 ! RENT1_HUMAN-Phosphoserine1107 relationship: location_of CCO:B0013855 ! RGC32_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0013872 ! RIN1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0013875 ! RIPK1_HUMAN-Phosphotyrosine384 relationship: location_of CCO:B0013886 ! RL18_HUMAN-Phosphoserine130 relationship: location_of CCO:B0013910 ! ROA1_HUMAN-Phosphoserine4 relationship: location_of CCO:B0013932 ! RS10_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013948 ! S100B_HUMAN-Blocked amino end (Ser)2 relationship: location_of CCO:B0013991 ! SEPT2_HUMAN-Phosphotyrosine17 relationship: location_of CCO:B0014015 ! SEPT9_HUMAN-Phosphoserine89 relationship: location_of CCO:B0014041 ! SFRS1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0014047 ! SGTA_HUMAN-Phosphothreonine303 relationship: location_of CCO:B0014054 ! SH3G2_HUMAN-Phosphoserine75 relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: location_of CCO:B0014085 ! SMC4_HUMAN-Phosphoserine1056 relationship: location_of CCO:B0014128 ! SN1L1_HUMAN-Phosphothreonine182 relationship: location_of CCO:B0014135 ! SN1L2_HUMAN-Phosphoserine587 relationship: location_of CCO:B0014148 ! SNUT1_HUMAN-Phosphoserine596 relationship: location_of CCO:B0014164 ! SPAG5_HUMAN-Phosphoserine249 relationship: location_of CCO:B0014198 ! SPTB2_HUMAN-Phosphothreonine2195 relationship: location_of CCO:B0014238 ! STA5B_HUMAN-Phosphotyrosine699 relationship: location_of CCO:B0014253 ! STK11_HUMAN-Phosphoserine428 relationship: location_of CCO:B0014254 ! STK4_HUMAN-Phosphothreonine183 relationship: location_of CCO:B0014264 ! STMN1_HUMAN-Phosphoserine63 relationship: location_of CCO:B0014267 ! STRAD_HUMAN-Phosphothreonine419 relationship: location_of CCO:B0014272 ! SUMO1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0014274 ! SYK_HUMAN-Phosphoserine596 relationship: location_of CCO:B0014295 ! TACC1_HUMAN-Phosphoserine52 relationship: location_of CCO:B0014304 ! TACC2_HUMAN-Phosphoserine2512 relationship: location_of CCO:B0014317 ! TBB5_HUMAN-Phosphotyrosine36 relationship: location_of CCO:B0014318 ! TBK1_HUMAN-Phosphoserine172 relationship: location_of CCO:B0014323 ! TCPB_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0014351 ! THIO_HUMAN-Phosphothreonine100 relationship: location_of CCO:B0014378 ! TIP60_HUMAN-Phosphoserine86 relationship: location_of CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: location_of CCO:B0014505 ! TP53B_HUMAN-Phosphothreonine1647 relationship: location_of CCO:B0014534 ! TRI37_HUMAN-Phosphoserine771 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0014549 ! TSYL2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0014558 ! TYB4_HUMAN-Phosphothreonine23 relationship: location_of CCO:B0014624 ! VIME_HUMAN-Phosphoserine10 relationship: location_of CCO:B0014658 ! WBP11_HUMAN-Phosphoserine253 relationship: location_of CCO:B0014673 ! WDR26_HUMAN-Phosphoserine121 relationship: location_of CCO:B0014702 ! WWC1_HUMAN-Phosphoserine927 relationship: location_of CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 relationship: location_of CCO:B0014725 ! YBOX1_HUMAN-Phosphoserine165 relationship: location_of CCO:B0014729 ! YES_HUMAN-Phosphotyrosine426 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0014938 ! AIFM1_HUMAN relationship: location_of CCO:B0015018 ! PPIP1_HUMAN relationship: location_of CCO:B0015164 ! HHIP_HUMAN relationship: location_of CCO:B0015270 ! DFFB_HUMAN relationship: location_of CCO:B0015638 ! ACTC_HUMAN relationship: location_of CCO:B0015644 ! ACTH_HUMAN relationship: location_of CCO:B0015682 ! EI2BA_HUMAN relationship: location_of CCO:B0015859 ! ANXA4_HUMAN relationship: location_of CCO:B0015979 ! MNDA_HUMAN relationship: location_of CCO:B0016049 ! I2C2_HUMAN relationship: location_of CCO:B0016186 ! IF4E_HUMAN relationship: location_of CCO:B0016191 ! I4E1B_HUMAN relationship: location_of CCO:B0016220 ! DNJB1_HUMAN relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0017601 ! ZNFX1_HUMAN relationship: location_of CCO:B0017622 ! 3BP5_HUMAN relationship: location_of CCO:B0017676 ! FGF13_HUMAN relationship: location_of CCO:B0018024 ! ZPR1_HUMAN relationship: location_of CCO:B0018046 ! NXF1_HUMAN relationship: location_of CCO:B0018189 ! PYDC1_HUMAN relationship: location_of CCO:B0018761 ! M3K13_HUMAN relationship: location_of CCO:B0018778 ! M3K12_HUMAN relationship: location_of CCO:B0018956 ! RASF3_HUMAN relationship: location_of CCO:B0018982 ! SNF8_HUMAN relationship: location_of CCO:B0019132 ! RHG17_HUMAN relationship: location_of CCO:B0019134 ! A6NCP5_HUMAN relationship: location_of CCO:B0019369 ! PIWL1_HUMAN relationship: location_of CCO:B0019510 ! TAOK3_HUMAN relationship: location_of CCO:B0019963 ! TISD_HUMAN relationship: location_of CCO:B0020040 ! A3RLL6_HUMAN relationship: location_of CCO:B0020117 ! Q92531_HUMAN relationship: location_of CCO:B0020119 ! Q68DD1_HUMAN relationship: location_of CCO:B0020122 ! FCN1_HUMAN relationship: location_of CCO:B0020218 ! CSEN_HUMAN relationship: location_of CCO:B0020282 ! SRY_HUMAN relationship: location_of CCO:B0020283 ! SOX15_HUMAN relationship: location_of CCO:B0020295 ! SOX2_HUMAN relationship: location_of CCO:B0020414 ! KC1G3_HUMAN relationship: location_of CCO:B0020417 ! KC1G1_HUMAN relationship: location_of CCO:B0020420 ! KC1G2_HUMAN relationship: location_of CCO:B0020529 ! IMA7_HUMAN relationship: location_of CCO:B0020591 ! RHOA_HUMAN relationship: location_of CCO:B0020771 ! RGS3_HUMAN relationship: location_of CCO:B0020787 ! RGS18_HUMAN relationship: location_of CCO:B0020951 ! MP2K7_HUMAN relationship: location_of CCO:B0020998 ! HELC1_HUMAN relationship: location_of CCO:B0021341 ! CSDC2_HUMAN relationship: location_of CCO:B0021348 ! Q15959_HUMAN relationship: location_of CCO:B0021435 ! ATF4_HUMAN relationship: location_of CCO:B0021707 ! CITE4_HUMAN relationship: location_of CCO:B0021718 ! NUP62_HUMAN relationship: location_of CCO:B0021811 ! SYWC_HUMAN relationship: location_of CCO:B0021834 ! MOAP1_HUMAN relationship: location_of CCO:B0022139 ! DYN1_HUMAN relationship: location_of CCO:B0022200 ! CSN4_HUMAN relationship: location_of CCO:B0022204 ! PSA5_HUMAN relationship: location_of CCO:B0022232 ! PPID_HUMAN relationship: location_of CCO:B0022296 ! Q3LRW1_HUMAN relationship: location_of CCO:B0022298 ! Q3LRW4_HUMAN relationship: location_of CCO:B0022300 ! P63_HUMAN relationship: location_of CCO:B0022308 ! Q1MSW9_HUMAN relationship: location_of CCO:B0022312 ! Q3LRW3_HUMAN relationship: location_of CCO:B0022452 ! PER3_HUMAN relationship: location_of CCO:B0022455 ! KAP2_HUMAN relationship: location_of CCO:B0022559 ! SLAP2_HUMAN relationship: location_of CCO:B0022753 ! MST4_HUMAN relationship: location_of CCO:B0022781 ! PIM1_HUMAN relationship: location_of CCO:B0023192 ! SMD1_HUMAN relationship: location_of CCO:B0023422 ! STAT2_HUMAN relationship: location_of CCO:B0024099 ! ARPC2_HUMAN relationship: location_of CCO:B0024129 ! LKHA4_HUMAN relationship: location_of CCO:B0024299 ! IPO11_HUMAN relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0024600 ! CEND1_HUMAN relationship: location_of CCO:B0024681 ! WDR68_HUMAN relationship: location_of CCO:B0024778 ! TNPO2_HUMAN relationship: location_of CCO:B0024842 ! RARB_HUMAN relationship: location_of CCO:B0025070 ! PDZD3_HUMAN relationship: location_of CCO:B0025212 ! SBDS_HUMAN relationship: location_of CCO:B0025823 ! TOB1_HUMAN relationship: location_of CCO:B0025990 ! 2A5B_HUMAN relationship: location_of CCO:B0026033 ! SPCS_HUMAN relationship: location_of CCO:B0026103 ! SORCN_HUMAN relationship: location_of CCO:B0026105 ! GRAN_HUMAN relationship: location_of CCO:B0026111 ! 2ABD_HUMAN relationship: location_of CCO:B0026166 ! LANC1_HUMAN relationship: location_of CCO:B0026252 ! NOXIN_HUMAN relationship: location_of CCO:B0026255 ! KLDC3_HUMAN relationship: location_of CCO:B0026256 ! RPRM_HUMAN relationship: location_of CCO:B0026267 ! DHB14_HUMAN relationship: location_of CCO:B0026268 ! CACO2_HUMAN relationship: location_of CCO:B0026347 ! ANDR_HUMAN-Phosphotyrosine915 relationship: location_of CCO:B0026369 ! EIF3E_HUMAN-Phosphothreonine439 relationship: location_of CCO:B0026377 ! EIF3K_HUMAN-Phosphoserine217 relationship: location_of CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: location_of CCO:B0026382 ! NF1_HUMAN-Phosphoserine2829 relationship: location_of CCO:B0026418 ! NUDT4_HUMAN relationship: location_of CCO:B0026419 ! NUDT3_HUMAN relationship: location_of CCO:B0026435 ! UK114_HUMAN relationship: location_of CCO:B0026467 ! HSF1_HUMAN relationship: location_of CCO:B0026489 ! HSF2_HUMAN relationship: location_of CCO:B0026531 ! CLOCK_HUMAN relationship: location_of CCO:B0026583 ! SNX6_HUMAN relationship: location_of CCO:B0026912 ! PEX6_HUMAN relationship: location_of CCO:B0026978 ! DPH3_HUMAN relationship: location_of CCO:B0027165 ! CDKL2_HUMAN relationship: location_of CCO:B0027514 ! PEBP1_HUMAN relationship: location_of CCO:B0027553 ! Q5FWY2_HUMAN relationship: location_of CCO:B0028186 ! ARP2_HUMAN relationship: location_of CCO:B0028677 ! PADI4_HUMAN relationship: location_of CCO:B0028914 ! AB1IP_HUMAN relationship: location_of CCO:B0029151 ! AMPM1_HUMAN relationship: location_of CCO:B0029172 ! TSAP1_HUMAN relationship: location_of CCO:B0029277 ! MKLN1_HUMAN relationship: location_of CCO:B0029357 ! EGLN2_HUMAN relationship: location_of CCO:B0029358 ! EGLN3_HUMAN relationship: location_of CCO:B0030251 ! GNA11_HUMAN relationship: location_of CCO:B0030278 ! RND1_HUMAN relationship: location_of CCO:B0030742 ! IDE_HUMAN relationship: location_of CCO:B0030752 ! CSN3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0030757 ! RIR2_HUMAN relationship: location_of CCO:B0030758 ! RIR2B_HUMAN relationship: location_of CCO:B0030804 ! PSB8_HUMAN relationship: location_of CCO:B0030806 ! PSB5_HUMAN relationship: location_of CCO:B0030929 ! PSB3_HUMAN relationship: location_of CCO:B0031007 ! PSB9_HUMAN relationship: location_of CCO:B0031015 ! PSB6_HUMAN relationship: location_of CCO:B0031065 ! FBLI1_HUMAN relationship: location_of CCO:B0031198 ! MOBL3_HUMAN relationship: location_of CCO:B0031313 ! DPYL1_HUMAN-Phosphotyrosine504 relationship: location_of CCO:B0031331 ! HS90A_HUMAN-Phosphotyrosine313 relationship: location_of CCO:B0031334 ! HSP7C_HUMAN-Phosphotyrosine41 relationship: location_of CCO:B0031337 ! LYN_HUMAN-Phosphotyrosine194 relationship: location_of CCO:B0031341 ! MTSS1_HUMAN-Phosphotyrosine526 relationship: location_of CCO:B0031342 ! MYO16_HUMAN-Phosphotyrosine1432 relationship: location_of CCO:B0031354 ! NEK2_HUMAN-Phosphoserine390 relationship: location_of CCO:B0031369 ! PTN6_HUMAN-Phosphotyrosine377 relationship: location_of CCO:B0031378 ! TBB2B_HUMAN-Phosphotyrosine36 relationship: location_of CCO:B0031540 ! APC2_HUMAN relationship: location_of CCO:B0031598 ! ARC1A_HUMAN relationship: location_of CCO:B0031823 ! MYO3B_HUMAN relationship: location_of CCO:B0032335 ! EID3_HUMAN relationship: location_of CCO:B0032349 ! CELR2_HUMAN relationship: location_of CCO:B0032391 ! MTND_HUMAN relationship: location_of CCO:B0032700 ! TGS1_HUMAN relationship: location_of CCO:B0032831 ! PRDC1_HUMAN relationship: location_of CCO:B0032848 ! GDIR1_HUMAN-N6-acetyllysine141 relationship: location_of CCO:B0032855 ! MYH10_HUMAN-Phosphothreonine1960 relationship: location_of CCO:B0032858 ! TAF10_HUMAN-N6-methyllysine189 relationship: location_of CCO:B0032975 ! TBPL2_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0033316 ! DEST_HUMAN relationship: location_of CCO:B0033320 ! COF1_HUMAN relationship: location_of CCO:B0033567 ! GHRL_HUMAN relationship: location_of CCO:B0033592 ! PPIC_HUMAN relationship: location_of CCO:B0033823 ! BACH_HUMAN relationship: location_of CCO:B0034007 ! PSB7_HUMAN relationship: location_of CCO:B0034060 ! FABP7_HUMAN relationship: location_of CCO:B0034070 ! FABPH_HUMAN relationship: location_of CCO:B0034076 ! RABP1_HUMAN relationship: location_of CCO:B0034503 ! ACTG_HUMAN-N-acetylglutamate2 relationship: location_of CCO:B0034567 ! ARP3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0034592 ! BPA1_HUMAN-Phosphothreonine224 relationship: location_of CCO:B0034678 ! COF2_HUMAN-Phosphoserine3 relationship: location_of CCO:B0034681 ! COR1B_HUMAN-Phosphoserine2 relationship: location_of CCO:B0034724 ! EFS_HUMAN-Phosphotyrosine253 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0034779 ! FABP4_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0034799 ! FOXO1_HUMAN-Phosphoserine319 relationship: location_of CCO:B0034805 ! FOXO6_HUMAN-Phosphoserine184 relationship: location_of CCO:B0034822 ! G3BP1_HUMAN-Omega-N-methylated arginine460 relationship: location_of CCO:B0034826 ! G3BP2_HUMAN-Phosphoserine225 relationship: location_of CCO:B0034845 ! GSK3B_HUMAN-Phosphoserine215 relationship: location_of CCO:B0034868 ! ICK_HUMAN-Phosphothreonine157 relationship: location_of CCO:B0034880 ! IQGA1_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0034952 ! K6PF_HUMAN-Phosphothreonine2 relationship: location_of CCO:B0034954 ! K6PL_HUMAN-Phosphotyrosine633 relationship: location_of CCO:B0034975 ! KAPCA_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0034978 ! KAPCB_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0034986 ! KCC1A_HUMAN-Phosphothreonine177 relationship: location_of CCO:B0034999 ! KCC4_HUMAN-Phosphoserine336 relationship: location_of CCO:B0035014 ! KCRB_HUMAN-Phosphoserine164 relationship: location_of CCO:B0035046 ! KPCB_HUMAN-Phosphothreonine504 relationship: location_of CCO:B0035064 ! KPCG_HUMAN-Phosphoserine687 relationship: location_of CCO:B0035087 ! LANC2_HUMAN-Phosphotyrosine295 relationship: location_of CCO:B0035120 ! LPXN_HUMAN-Phosphotyrosine62 relationship: location_of CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: location_of CCO:B0035196 ! MK10_HUMAN-Phosphotyrosine223 relationship: location_of CCO:B0035198 ! MK14_HUMAN-Phosphotyrosine182 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0035225 ! MYH1_HUMAN-Phosphothreonine1933 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0035311 ! NTKL_HUMAN-Phosphoserine754 relationship: location_of CCO:B0035344 ! PCBP1_HUMAN-Phosphoserine190 relationship: location_of CCO:B0035357 ! PDXK_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035383 ! PKN2_HUMAN-Phosphoserine360 relationship: location_of CCO:B0035392 ! PKN3_HUMAN-Phosphoserine544 relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0035418 ! PPAC_HUMAN-Phosphotyrosine133 relationship: location_of CCO:B0035477 ! PSA7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0035478 ! PSB1_HUMAN-Phosphotyrosine150 relationship: location_of CCO:B0035479 ! PSB2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035507 ! RAP1B_HUMAN-ADP-ribosylserine39 relationship: location_of CCO:B0035539 ! RD23B_HUMAN-Phosphoserine160 relationship: location_of CCO:B0035571 ! RHG07_HUMAN-Phosphoserine305 relationship: location_of CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: location_of CCO:B0035665 ! SMAP2_HUMAN-Phosphoserine219 relationship: location_of CCO:B0035692 ! SRPK2_HUMAN-Phosphotyrosine319 relationship: location_of CCO:B0035696 ! ST38L_HUMAN-Phosphoserine282 relationship: location_of CCO:B0035699 ! STAT6_HUMAN-Phosphotyrosine641 relationship: location_of CCO:B0035700 ! STK24_HUMAN-Phosphothreonine18 relationship: location_of CCO:B0035707 ! STK25_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0035712 ! STMN2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0035719 ! STMN3_HUMAN-Phosphoserine68 relationship: location_of CCO:B0035747 ! TB182_HUMAN-Phosphoserine1621 relationship: location_of CCO:B0035772 ! TERA_HUMAN-Phosphotyrosine805 relationship: location_of CCO:B0035773 ! TGFI1_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0035781 ! THOC4_HUMAN-Phosphoserine183 relationship: location_of CCO:B0035785 ! TISB_HUMAN-Phosphoserine54 relationship: location_of CCO:B0035829 ! WDHD1_HUMAN-Phosphoserine374 relationship: location_of CCO:B0035939 ! C8AP2_HUMAN relationship: location_of CCO:B0035975 ! ACACA_HUMAN-Phosphothreonine58 relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0035990 ! CCNG2_HUMAN-Phosphoserine220 relationship: location_of CCO:B0036005 ! FOXO4_HUMAN-Phosphoserine111 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0036035 ! THOP1_HUMAN-Phosphotyrosine278 relationship: location_of CCO:B0036139 ! SENP2_HUMAN relationship: location_of CCO:B0036172 ! GSTO1_HUMAN relationship: location_of CCO:B0036526 ! MYLK2_HUMAN relationship: location_of CCO:B0036875 ! EXOC5_HUMAN relationship: location_of CCO:B0036957 ! HPRT_HUMAN relationship: location_of CCO:B0037017 ! ARHG4_HUMAN relationship: location_of CCO:B0037024 ! ARHG9_HUMAN relationship: location_of CCO:B0037117 ! TNIP2_HUMAN relationship: location_of CCO:B0037152 ! DUS16_HUMAN relationship: location_of CCO:B0037159 ! DUS8_HUMAN relationship: location_of CCO:B0037398 ! PXK_HUMAN relationship: location_of CCO:B0037436 ! XPO5_HUMAN relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0037580 ! PMM1_HUMAN relationship: location_of CCO:B0037714 ! DNM3L_HUMAN relationship: location_of CCO:B0037934 ! IRF9_HUMAN relationship: location_of CCO:B0037975 ! ZN175_HUMAN relationship: location_of CCO:B0038093 ! ABI3_HUMAN relationship: location_of CCO:B0038095 ! ABI2_HUMAN relationship: location_of CCO:B0038197 ! PFD3_HUMAN relationship: location_of CCO:B0038221 ! GSTM3_HUMAN relationship: location_of CCO:B0039306 ! ADHX_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039321 ! ARC1B_HUMAN-Phosphoserine310 relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039372 ! CPIN1_HUMAN-Phosphoserine185 relationship: location_of CCO:B0039378 ! DAPK2_HUMAN-Phosphoserine318 relationship: location_of CCO:B0039404 ! DNM3A_HUMAN-Phosphoserine105 relationship: location_of CCO:B0039447 ! GSTM1_HUMAN-Phosphotyrosine23 relationship: location_of CCO:B0039457 ! HNF4A_HUMAN-Phosphothreonine429 relationship: location_of CCO:B0039463 ! IF5A1_HUMAN-Blocked amino end (Ala)2 relationship: location_of CCO:B0039472 ! IMA1_HUMAN-Phosphothreonine3 relationship: location_of CCO:B0039477 ! IRF7_HUMAN-Phosphoserine484 relationship: location_of CCO:B0039479 ! K1967_HUMAN-Phosphothreonine454 relationship: location_of CCO:B0039483 ! KI18A_HUMAN-Phosphoserine357 relationship: location_of CCO:B0039502 ! MARK1_HUMAN-Phosphoserine394 relationship: location_of CCO:B0039518 ! MAST1_HUMAN-Phosphoserine161 relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0039573 ! NSF_HUMAN-Phosphotyrosine259 relationship: location_of CCO:B0039592 ! PLST_HUMAN-Phosphoserine474 relationship: location_of CCO:B0039596 ! PREX1_HUMAN-Phosphoserine436 relationship: location_of CCO:B0039597 ! PRS10_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: location_of CCO:B0039618 ! RGPS2_HUMAN-Phosphoserine343 relationship: location_of CCO:B0039660 ! STK38_HUMAN-Phosphothreonine26 relationship: location_of CCO:B0039662 ! SYG_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0039664 ! SYUA_HUMAN-Phosphoserine87 relationship: location_of CCO:B0039670 ! TALDO_HUMAN-Phosphoserine237 relationship: location_of CCO:B0039671 ! TCTP_HUMAN-Phosphoserine46 relationship: location_of CCO:B0039700 ! TTP_HUMAN-Phosphoserine323 relationship: location_of CCO:B0039762 ! EXOS2_HUMAN-Phosphotyrosine46 relationship: location_of CCO:B0039862 ! KLK6_HUMAN relationship: location_of CCO:B0039927 ! K1C20_HUMAN-Phosphoserine13 relationship: location_of CCO:B0039947 ! STRA8_HUMAN relationship: location_of CCO:B0039948 ! ZFP42_HUMAN relationship: location_of CCO:B0039949 ! FSD1_HUMAN relationship: location_of CCO:B0040253 ! IMA4_HUMAN relationship: location_of CCO:B0040310 ! RF1M_HUMAN relationship: location_of CCO:B0040467 ! CASP1_HUMAN relationship: location_of CCO:B0040646 ! PGK1_HUMAN-Phosphothreonine243 relationship: location_of CCO:B0040650 ! PUR2_HUMAN-Phosphotyrosine348 relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0040684 ! REBL1_HUMAN relationship: location_of CCO:B0041106 ! 1433T_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041126 ! BCL3_HUMAN-Phosphoserine394 relationship: location_of CCO:B0041145 ! IKBA_HUMAN-Phosphoserine283 relationship: location_of CCO:B0041151 ! IKBB_HUMAN-Phosphoserine315 relationship: location_of CCO:B0041155 ! KI13B_HUMAN-Phosphoserine1644 relationship: location_of CCO:B0041164 ! NEMO_HUMAN-Phosphoserine43 relationship: location_of CCO:B0041168 ! OGT1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041173 ! RASH_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041195 ! SIRT2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0041207 ! TF65_HUMAN-N6-acetyllysine122 relationship: location_of CCO:B0041241 ! CCDB1_HUMAN relationship: location_of CCO:B0041243 ! PSA2_HUMAN relationship: location_of CCO:B0041244 ! PSA4_HUMAN relationship: location_of CCO:B0041245 ! PSB4_HUMAN relationship: location_of CCO:B0041246 ! PRS7_HUMAN relationship: location_of CCO:B0041247 ! PRS6B_HUMAN relationship: location_of CCO:B0041251 ! PSA6_HUMAN relationship: location_of CCO:B0041253 ! PRS8_HUMAN relationship: location_of CCO:B0041257 ! E4F1_HUMAN relationship: location_of CCO:B0041258 ! XAF1_HUMAN relationship: location_of CCO:B0041261 ! ERF3B_HUMAN relationship: location_of CCO:B0041284 ! ANXA3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041299 ! EI2BG_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041305 ! HBXIP_HUMAN-Phosphoserine26 relationship: location_of CCO:B0041315 ! PRS6A_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041339 ! RBX1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041344 ! TCPE_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041371 ! RHG15_HUMAN relationship: location_of CCO:B0041523 ! ANK1_HUMAN relationship: location_of CCO:B0041526 ! ANK3_HUMAN relationship: location_of CCO:B0041769 ! APOL3_HUMAN relationship: location_of CCO:B0041800 ! CAN1_HUMAN relationship: location_of CCO:B0041821 ! CAN2_HUMAN relationship: location_of CCO:B0042018 ! APIP_HUMAN relationship: location_of CCO:B0042291 ! IMPA1_HUMAN relationship: location_of CCO:B0042408 ! HIF3A_HUMAN relationship: location_of CCO:B0042506 ! DESP_HUMAN relationship: location_of CCO:B0043195 ! ANK2_HUMAN-Phosphoserine1475 relationship: location_of CCO:B0043213 ! BNIP2_HUMAN-Phosphoserine114 relationship: location_of CCO:B0043260 ! EF1A2_HUMAN-N6,N6,N6-trimethyllysine165 relationship: location_of CCO:B0043273 ! FLNA_HUMAN-Phosphoserine2284 relationship: location_of CCO:B0043276 ! FLNB_HUMAN-Phosphoserine983 relationship: location_of CCO:B0043283 ! GLIS2_HUMAN-Phosphoserine245 relationship: location_of CCO:B0043290 ! IF2A_HUMAN-Phosphoserine49 relationship: location_of CCO:B0043358 ! RHG27_HUMAN-Phosphotyrosine228 relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0043460 ! CENA1_HUMAN-Phosphothreonine276 relationship: location_of CCO:B0043475 ! NCOA3_HUMAN-Phosphoserine857 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0043535 ! UB2E3_HUMAN relationship: location_of CCO:B0043604 ! DEDD_HUMAN relationship: location_of CCO:B0043706 ! SPSB4_HUMAN relationship: location_of CCO:B0043707 ! SPSB2_HUMAN relationship: location_of CCO:B0043708 ! SPSB1_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0043817 ! NGX6_HUMAN relationship: location_of CCO:B0043822 ! EDN1_HUMAN relationship: location_of CCO:B0043825 ! RS15A_HUMAN relationship: location_of CCO:B0043827 ! HHEX_HUMAN relationship: location_of CCO:B0043831 ! H1FOO_HUMAN relationship: location_of CCO:B0043834 ! URG4_HUMAN relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: location_of CCO:B0048149 ! 1433G_HUMAN-Phosphothreonine145 relationship: location_of CCO:B0048179 ! BMX_HUMAN-Phosphotyrosine224 relationship: location_of CCO:B0048217 ! DAXX_HUMAN-Phosphoserine178 relationship: location_of CCO:B0048224 ! DCP1A_HUMAN-Phosphothreonine531 relationship: location_of CCO:B0048231 ! DLGP5_HUMAN-Phosphothreonine401 relationship: location_of CCO:B0048247 ! EDC3_HUMAN-Phosphoserine161 relationship: location_of CCO:B0048271 ! GRLF1_HUMAN-Phosphoserine970 relationship: location_of CCO:B0048274 ! HCFC2_HUMAN-Phosphotyrosine159 relationship: location_of CCO:B0048340 ! NPM_HUMAN-Phosphothreonine279 relationship: location_of CCO:B0048362 ! PSRC1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0048582 ! ELP2_HUMAN relationship: location_of CCO:B0048588 ! ZN675_HUMAN relationship: location_of CCO:B0048656 ! PO5F1_HUMAN relationship: location_of CCO:B0048870 ! CRIP1_HUMAN relationship: location_of CCO:B0048898 ! RGPS1_HUMAN relationship: location_of CCO:B0049166 ! Q5T4B6_HUMAN relationship: location_of CCO:B0049167 ! TMSL2_HUMAN relationship: location_of CCO:B0049174 ! TMSL1_HUMAN relationship: location_of CCO:B0049175 ! TMSL3_HUMAN relationship: location_of CCO:B0049176 ! TYB4Y_HUMAN relationship: location_of CCO:B0049179 ! TMSL6_HUMAN relationship: location_of CCO:B0049379 ! GNAT3_HUMAN relationship: location_of CCO:B0049425 ! CNTF_HUMAN relationship: location_of CCO:B0049689 ! ATX3_HUMAN relationship: location_of CCO:B0049848 ! RNF4_HUMAN relationship: location_of CCO:B0049892 ! DBPA_HUMAN relationship: location_of CCO:B0049899 ! YBOX2_HUMAN relationship: location_of CCO:B0050004 ! PANK4_HUMAN relationship: location_of CCO:B0050171 ! UBE2K_HUMAN relationship: location_of CCO:B0050294 ! HMGB2_HUMAN relationship: location_of CCO:B0050348 ! AHRR_HUMAN relationship: location_of CCO:B0050534 ! CNOT8_HUMAN relationship: location_of CCO:B0050581 ! IPO8_HUMAN relationship: location_of CCO:B0050696 ! IDHC_HUMAN relationship: location_of CCO:B0050722 ! GCH1_HUMAN relationship: location_of CCO:B0050820 ! NT2NL_HUMAN relationship: location_of CCO:B0051353 ! GBRL1_HUMAN relationship: location_of CCO:B0051549 ! IF5_HUMAN relationship: location_of CCO:B0051562 ! SRP09_HUMAN relationship: location_of CCO:B0051613 ! VILI_HUMAN relationship: location_of CCO:B0052277 ! ADSV_HUMAN-Phosphotyrosine599 relationship: location_of CCO:B0052303 ! AVIL_HUMAN-Phosphotyrosine758 relationship: location_of CCO:B0052306 ! C1TC_HUMAN-Phosphothreonine786 relationship: location_of CCO:B0052319 ! CCHCR_HUMAN-Phosphoserine88 relationship: location_of CCO:B0052329 ! CHSP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0052344 ! CNOT2_HUMAN-Phosphoserine101 relationship: location_of CCO:B0052345 ! CNOT6_HUMAN-Phosphothreonine146 relationship: location_of CCO:B0052375 ! EPIPL_HUMAN-Phosphoserine2691 relationship: location_of CCO:B0052394 ! FOXO3_HUMAN-Phosphothreonine427 relationship: location_of CCO:B0052404 ! GELS_HUMAN-Phosphotyrosine603 relationship: location_of CCO:B0052463 ! IRS1_HUMAN-Phosphotyrosine632 relationship: location_of CCO:B0052556 ! MAP2_HUMAN-Phosphothreonine1613 relationship: location_of CCO:B0052646 ! PLEC1_HUMAN-Phosphoserine4382 relationship: location_of CCO:B0052719 ! S10A7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 relationship: location_of CCO:B0052884 ! TYB10_HUMAN-N6-acetyllysine4 relationship: location_of CCO:B0052892 ! WDR1_HUMAN-Phosphotyrosine238 relationship: location_of CCO:B0053705 ! RHG10_HUMAN relationship: location_of CCO:B0053710 ! YE018_HUMAN relationship: location_of CCO:B0054020 ! A8MT47_HUMAN relationship: location_of CCO:B0054036 ! A8MU01_HUMAN relationship: location_of CCO:B0054154 ! MI4GD_HUMAN relationship: location_of CCO:B0054293 ! EYA2_HUMAN relationship: location_of CCO:B0054296 ! LEG9_HUMAN relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054315 ! O00366_HUMAN relationship: location_of CCO:B0054319 ! IF2B3_HUMAN relationship: location_of CCO:B0054320 ! DNM1L_HUMAN relationship: location_of CCO:B0054322 ! LST1_HUMAN relationship: location_of CCO:B0054323 ! TRAF5_HUMAN relationship: location_of CCO:B0054345 ! SOCS2_HUMAN relationship: location_of CCO:B0054347 ! SOCS7_HUMAN relationship: location_of CCO:B0054349 ! SOCS6_HUMAN relationship: location_of CCO:B0054351 ! G3PT_HUMAN relationship: location_of CCO:B0054354 ! TPPC2_HUMAN relationship: location_of CCO:B0054357 ! BORG1_HUMAN relationship: location_of CCO:B0054363 ! DVL1_HUMAN relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0054370 ! ITBP1_HUMAN relationship: location_of CCO:B0054371 ! APAF_HUMAN relationship: location_of CCO:B0054375 ! TNF11_HUMAN relationship: location_of CCO:B0054390 ! TX1B3_HUMAN relationship: location_of CCO:B0054391 ! GIPC1_HUMAN relationship: location_of CCO:B0054395 ! HNRDL_HUMAN relationship: location_of CCO:B0054403 ! MCF2L_HUMAN relationship: location_of CCO:B0054406 ! SMAD7_HUMAN relationship: location_of CCO:B0054407 ! FYB_HUMAN relationship: location_of CCO:B0054410 ! MYT2_HUMAN relationship: location_of CCO:B0054413 ! BRAC_HUMAN relationship: location_of CCO:B0054414 ! SMAD9_HUMAN relationship: location_of CCO:B0054419 ! CLIC2_HUMAN relationship: location_of CCO:B0054441 ! ARPC5_HUMAN relationship: location_of CCO:B0054443 ! SOCS1_HUMAN relationship: location_of CCO:B0054463 ! RBM9_HUMAN relationship: location_of CCO:B0054478 ! RASL2_HUMAN relationship: location_of CCO:B0054490 ! TNF14_HUMAN relationship: location_of CCO:B0054493 ! AKA10_HUMAN relationship: location_of CCO:B0054499 ! SPY1_HUMAN relationship: location_of CCO:B0054500 ! SPY3_HUMAN relationship: location_of CCO:B0054519 ! TLX2_HUMAN relationship: location_of CCO:B0054531 ! AIRE_HUMAN relationship: location_of CCO:B0054547 ! MCM3A_HUMAN relationship: location_of CCO:B0054566 ! CIDEA_HUMAN relationship: location_of CCO:B0054567 ! IF4E2_HUMAN relationship: location_of CCO:B0054577 ! CYTIP_HUMAN relationship: location_of CCO:B0054578 ! PTGD2_HUMAN relationship: location_of CCO:B0054582 ! EDF1_HUMAN relationship: location_of CCO:B0054583 ! KIN17_HUMAN relationship: location_of CCO:B0054584 ! DIAP2_HUMAN relationship: location_of CCO:B0054591 ! NOL3_HUMAN relationship: location_of CCO:B0054602 ! ROCK2_HUMAN relationship: location_of CCO:B0054611 ! CNOT3_HUMAN relationship: location_of CCO:B0054619 ! GCYB2_HUMAN relationship: location_of CCO:B0054636 ! USH2A_HUMAN relationship: location_of CCO:B0054668 ! GRAP2_HUMAN relationship: location_of CCO:B0054681 ! TRIO_HUMAN relationship: location_of CCO:B0054690 ! S14L2_HUMAN relationship: location_of CCO:B0054693 ! PDE9A_HUMAN relationship: location_of CCO:B0054724 ! O95098_HUMAN relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0054750 ! ATG7_HUMAN relationship: location_of CCO:B0054753 ! TFIP8_HUMAN relationship: location_of CCO:B0054758 ! ZFYV9_HUMAN relationship: location_of CCO:B0054763 ! BAG4_HUMAN relationship: location_of CCO:B0054765 ! GNAS3_HUMAN relationship: location_of CCO:B0054775 ! CNOT4_HUMAN relationship: location_of CCO:B0054782 ! EYA4_HUMAN relationship: location_of CCO:B0054797 ! DCMC_HUMAN relationship: location_of CCO:B0054798 ! CLIC3_HUMAN relationship: location_of CCO:B0054801 ! DDAH2_HUMAN relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0054845 ! CALC_HUMAN relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054896 ! PAI2_HUMAN relationship: location_of CCO:B0054902 ! AGAL_HUMAN relationship: location_of CCO:B0054905 ! DPOLB_HUMAN relationship: location_of CCO:B0054907 ! CALCA_HUMAN relationship: location_of CCO:B0054920 ! CO1A2_HUMAN relationship: location_of CCO:B0054921 ! TNR16_HUMAN relationship: location_of CCO:B0054922 ! GLI1_HUMAN relationship: location_of CCO:B0054925 ! MCR_HUMAN relationship: location_of CCO:B0054940 ! PO2F2_HUMAN relationship: location_of CCO:B0054941 ! DOPO_HUMAN relationship: location_of CCO:B0054942 ! LEG1_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0054999 ! PTHR_HUMAN relationship: location_of CCO:B0055023 ! HCLS1_HUMAN relationship: location_of CCO:B0055051 ! EPB42_HUMAN relationship: location_of CCO:B0055097 ! LOX12_HUMAN relationship: location_of CCO:B0055127 ! NEBU_HUMAN relationship: location_of CCO:B0055135 ! SCF_HUMAN relationship: location_of CCO:B0055155 ! S10A1_HUMAN relationship: location_of CCO:B0055180 ! ARBK1_HUMAN relationship: location_of CCO:B0055194 ! APEX1_HUMAN relationship: location_of CCO:B0055198 ! 5HT2A_HUMAN relationship: location_of CCO:B0055212 ! RABP2_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055249 ! PRDX2_HUMAN relationship: location_of CCO:B0055250 ! ARRB2_HUMAN relationship: location_of CCO:B0055255 ! OTX2_HUMAN relationship: location_of CCO:B0055267 ! GCYA2_HUMAN relationship: location_of CCO:B0055271 ! GRK5_HUMAN relationship: location_of CCO:B0055278 ! CAH8_HUMAN relationship: location_of CCO:B0055282 ! SFTPD_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055311 ! ARRC_HUMAN relationship: location_of CCO:B0055316 ! SRP14_HUMAN relationship: location_of CCO:B0055320 ! IF4A3_HUMAN relationship: location_of CCO:B0055322 ! COIA1_HUMAN relationship: location_of CCO:B0055324 ! CAPG_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055351 ! CASP3_HUMAN relationship: location_of CCO:B0055356 ! NSG1_HUMAN relationship: location_of CCO:B0055387 ! OMP_HUMAN relationship: location_of CCO:B0055392 ! AL1A3_HUMAN relationship: location_of CCO:B0055410 ! KC1A_HUMAN relationship: location_of CCO:B0055421 ! FNTA_HUMAN relationship: location_of CCO:B0055425 ! DGKG_HUMAN relationship: location_of CCO:B0055428 ! CXCR3_HUMAN relationship: location_of CCO:B0055433 ! RGS6_HUMAN relationship: location_of CCO:B0055434 ! EI2BB_HUMAN relationship: location_of CCO:B0055436 ! HINT1_HUMAN relationship: location_of CCO:B0055446 ! MMP14_HUMAN relationship: location_of CCO:B0055462 ! PLCD1_HUMAN relationship: location_of CCO:B0055474 ! CCR5_HUMAN relationship: location_of CCO:B0055483 ! NR0B1_HUMAN relationship: location_of CCO:B0055486 ! GDIR2_HUMAN relationship: location_of CCO:B0055508 ! ARFP2_HUMAN relationship: location_of CCO:B0055516 ! DVL1L_HUMAN relationship: location_of CCO:B0055525 ! NR1H2_HUMAN relationship: location_of CCO:B0055530 ! CASP7_HUMAN relationship: location_of CCO:B0055534 ! CAD13_HUMAN relationship: location_of CCO:B0055535 ! PKNX1_HUMAN relationship: location_of CCO:B0055547 ! SOX10_HUMAN relationship: location_of CCO:B0055561 ! SELB_HUMAN relationship: location_of CCO:B0055572 ! TIRAP_HUMAN relationship: location_of CCO:B0055574 ! NAL12_HUMAN relationship: location_of CCO:B0055605 ! CSN2_HUMAN relationship: location_of CCO:B0055611 ! PHS_HUMAN relationship: location_of CCO:B0055615 ! BTG1_HUMAN relationship: location_of CCO:B0055616 ! ARF6_HUMAN relationship: location_of CCO:B0055618 ! TBPL1_HUMAN relationship: location_of CCO:B0055620 ! CNBP_HUMAN relationship: location_of CCO:B0055637 ! IGBP1_HUMAN relationship: location_of CCO:B0055647 ! RELN_HUMAN relationship: location_of CCO:B0055650 ! ELF3_HUMAN relationship: location_of CCO:B0055656 ! SSBP2_HUMAN relationship: location_of CCO:B0055662 ! ARF5_HUMAN relationship: location_of CCO:B0055689 ! TSPY1_HUMAN relationship: location_of CCO:B0055695 ! SPIB_HUMAN relationship: location_of CCO:B0055697 ! SC6A3_HUMAN relationship: location_of CCO:B0055699 ! ROR1_HUMAN relationship: location_of CCO:B0055705 ! GCYA3_HUMAN relationship: location_of CCO:B0055706 ! GCYB1_HUMAN relationship: location_of CCO:B0055724 ! PTHR1_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055735 ! LGUL_HUMAN relationship: location_of CCO:B0055765 ! PTN11_HUMAN relationship: location_of CCO:B0055766 ! REG3A_HUMAN relationship: location_of CCO:B0055775 ! PRDX1_HUMAN relationship: location_of CCO:B0055782 ! COGA1_HUMAN relationship: location_of CCO:B0055806 ! ZN415_HUMAN relationship: location_of CCO:B0055824 ! ADIG_HUMAN relationship: location_of CCO:B0055859 ! NFAC3_HUMAN relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0055869 ! FLII_HUMAN relationship: location_of CCO:B0055874 ! TRAF3_HUMAN relationship: location_of CCO:B0055882 ! PRDX4_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055904 ! JIP2_HUMAN relationship: location_of CCO:B0055907 ! ILK_HUMAN relationship: location_of CCO:B0055917 ! BIRC3_HUMAN relationship: location_of CCO:B0055921 ! OLIG2_HUMAN relationship: location_of CCO:B0055929 ! NDF1_HUMAN relationship: location_of CCO:B0055932 ! DGKZ_HUMAN relationship: location_of CCO:B0055933 ! GRAP_HUMAN relationship: location_of CCO:B0055940 ! AVR2B_HUMAN relationship: location_of CCO:B0055952 ! C1D_HUMAN relationship: location_of CCO:B0055953 ! CAYP1_HUMAN relationship: location_of CCO:B0055961 ! SRTD2_HUMAN relationship: location_of CCO:B0055962 ! KEAP1_HUMAN relationship: location_of CCO:B0055986 ! HES1_HUMAN relationship: location_of CCO:B0056009 ! IRF3_HUMAN relationship: location_of CCO:B0056011 ! PSF1_HUMAN relationship: location_of CCO:B0056049 ! TEBP_HUMAN relationship: location_of CCO:B0056052 ! RASA2_HUMAN relationship: location_of CCO:B0056058 ! ANKR1_HUMAN relationship: location_of CCO:B0056063 ! CYH1_HUMAN relationship: location_of CCO:B0056070 ! RGN_HUMAN relationship: location_of CCO:B0056077 ! DIXC1_HUMAN relationship: location_of CCO:B0056092 ! TRIP4_HUMAN relationship: location_of CCO:B0056098 ! T22D1_HUMAN relationship: location_of CCO:B0056129 ! NF2L2_HUMAN relationship: location_of CCO:B0056142 ! CRY1_HUMAN relationship: location_of CCO:B0056148 ! B2LA1_HUMAN relationship: location_of CCO:B0056166 ! MAPK3_HUMAN relationship: location_of CCO:B0056176 ! DGKD_HUMAN relationship: location_of CCO:B0056200 ! MICA_HUMAN relationship: location_of CCO:B0056222 ! AS250_HUMAN relationship: location_of CCO:B0056234 ! CORL2_HUMAN relationship: location_of CCO:B0056243 ! LRRK1_HUMAN relationship: location_of CCO:B0056256 ! PKHG6_HUMAN relationship: location_of CCO:B0056288 ! PAR14_HUMAN relationship: location_of CCO:B0056304 ! CRY2_HUMAN relationship: location_of CCO:B0056307 ! CERKL_HUMAN relationship: location_of CCO:B0056320 ! PLCH1_HUMAN relationship: location_of CCO:B0056440 ! TAF7L_HUMAN relationship: location_of CCO:B0056454 ! Q5JPN0_HUMAN relationship: location_of CCO:B0056489 ! SOLH1_HUMAN relationship: location_of CCO:B0056515 ! DGKK_HUMAN relationship: location_of CCO:B0056521 ! COL12_HUMAN relationship: location_of CCO:B0056531 ! LRRK2_HUMAN relationship: location_of CCO:B0056547 ! ARH_HUMAN relationship: location_of CCO:B0056564 ! ZEP3_HUMAN relationship: location_of CCO:B0056579 ! Q5T4Y8_HUMAN relationship: location_of CCO:B0056639 ! RAIN_HUMAN relationship: location_of CCO:B0056646 ! MRCKA_HUMAN relationship: location_of CCO:B0056675 ! MAK10_HUMAN relationship: location_of CCO:B0056676 ! RRAGB_HUMAN relationship: location_of CCO:B0056697 ! RPGP2_HUMAN relationship: location_of CCO:B0056725 ! NXN_HUMAN relationship: location_of CCO:B0056729 ! MRCKG_HUMAN relationship: location_of CCO:B0056842 ! R7BP_HUMAN relationship: location_of CCO:B0056848 ! NARGL_HUMAN relationship: location_of CCO:B0056874 ! BORG3_HUMAN relationship: location_of CCO:B0056892 ! Q6P5Z4_HUMAN relationship: location_of CCO:B0056898 ! CNKR3_HUMAN relationship: location_of CCO:B0056928 ! Q6QEF7_HUMAN relationship: location_of CCO:B0056942 ! SARM1_HUMAN relationship: location_of CCO:B0056947 ! Z322A_HUMAN relationship: location_of CCO:B0056960 ! KSR2_HUMAN relationship: location_of CCO:B0056968 ! NPSR1_HUMAN relationship: location_of CCO:B0056974 ! DNMBP_HUMAN relationship: location_of CCO:B0057005 ! LN28B_HUMAN relationship: location_of CCO:B0057029 ! FGD5_HUMAN relationship: location_of CCO:B0057033 ! Q6ZQV2_HUMAN relationship: location_of CCO:B0057066 ! Q6ZT62_HUMAN relationship: location_of CCO:B0057070 ! Q6ZTJ5_HUMAN relationship: location_of CCO:B0057092 ! RAPH1_HUMAN relationship: location_of CCO:B0057117 ! Q7L3H5_HUMAN relationship: location_of CCO:B0057119 ! RRAGA_HUMAN relationship: location_of CCO:B0057124 ! NLRC3_HUMAN relationship: location_of CCO:B0057127 ! PTF1A_HUMAN relationship: location_of CCO:B0057180 ! RHG22_HUMAN relationship: location_of CCO:B0057184 ! CPEB2_HUMAN relationship: location_of CCO:B0057194 ! SPRE2_HUMAN relationship: location_of CCO:B0057198 ! FGD2_HUMAN relationship: location_of CCO:B0057209 ! TAF8_HUMAN relationship: location_of CCO:B0057245 ! RIP_HUMAN relationship: location_of CCO:B0057254 ! NOXA1_HUMAN relationship: location_of CCO:B0057255 ! EST1A_HUMAN relationship: location_of CCO:B0057257 ! DTX2_HUMAN relationship: location_of CCO:B0057258 ! Q86UY3_HUMAN relationship: location_of CCO:B0057265 ! VPS36_HUMAN relationship: location_of CCO:B0057267 ! GEFT_HUMAN relationship: location_of CCO:B0057278 ! GPBP1_HUMAN relationship: location_of CCO:B0057284 ! CARM1_HUMAN relationship: location_of CCO:B0057292 ! DGKH_HUMAN relationship: location_of CCO:B0057293 ! TCAM2_HUMAN relationship: location_of CCO:B0057294 ! CEP57_HUMAN relationship: location_of CCO:B0057298 ! DTX1_HUMAN relationship: location_of CCO:B0057307 ! HOME1_HUMAN relationship: location_of CCO:B0057312 ! MIB1_HUMAN relationship: location_of CCO:B0057330 ! AEBP1_HUMAN relationship: location_of CCO:B0057335 ! UN5CL_HUMAN relationship: location_of CCO:B0057337 ! GRP3_HUMAN relationship: location_of CCO:B0057340 ! WASF4_HUMAN relationship: location_of CCO:B0057343 ! TIAM2_HUMAN relationship: location_of CCO:B0057398 ! RASEF_HUMAN relationship: location_of CCO:B0057419 ! ABRA_HUMAN relationship: location_of CCO:B0057426 ! SIX5_HUMAN relationship: location_of CCO:B0057431 ! CRPAK_HUMAN relationship: location_of CCO:B0057433 ! RGNEF_HUMAN relationship: location_of CCO:B0057438 ! RHG24_HUMAN relationship: location_of CCO:B0057450 ! AGGF1_HUMAN relationship: location_of CCO:B0057481 ! IF4E3_HUMAN relationship: location_of CCO:B0057498 ! KC1AL_HUMAN relationship: location_of CCO:B0057537 ! DTX3_HUMAN relationship: location_of CCO:B0057540 ! ASCC1_HUMAN relationship: location_of CCO:B0057544 ! ZN383_HUMAN relationship: location_of CCO:B0057552 ! SMYD1_HUMAN relationship: location_of CCO:B0057556 ! UN13C_HUMAN relationship: location_of CCO:B0057590 ! SRFB1_HUMAN relationship: location_of CCO:B0057591 ! NGDN_HUMAN relationship: location_of CCO:B0057597 ! ZN397_HUMAN relationship: location_of CCO:B0057602 ! REPS2_HUMAN relationship: location_of CCO:B0057886 ! PP14C_HUMAN relationship: location_of CCO:B0057916 ! CERK1_HUMAN relationship: location_of CCO:B0057927 ! GRP4_HUMAN relationship: location_of CCO:B0057946 ! DDFL1_HUMAN relationship: location_of CCO:B0057948 ! DERP6_HUMAN relationship: location_of CCO:B0057954 ! RN128_HUMAN relationship: location_of CCO:B0057969 ! DUS19_HUMAN relationship: location_of CCO:B0057993 ! PPR1C_HUMAN relationship: location_of CCO:B0057994 ! TWST2_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058009 ! EDAD_HUMAN relationship: location_of CCO:B0058011 ! NELFB_HUMAN relationship: location_of CCO:B0058016 ! STON2_HUMAN relationship: location_of CCO:B0058017 ! PSPC1_HUMAN relationship: location_of CCO:B0058018 ! GPR98_HUMAN relationship: location_of CCO:B0058039 ! NANO1_HUMAN relationship: location_of CCO:B0058055 ! RPGF4_HUMAN relationship: location_of CCO:B0058077 ! FAN_HUMAN relationship: location_of CCO:B0058088 ! TAF4B_HUMAN relationship: location_of CCO:B0058092 ! DPF1_HUMAN relationship: location_of CCO:B0058093 ! STAM1_HUMAN relationship: location_of CCO:B0058101 ! FRAT1_HUMAN relationship: location_of CCO:B0058102 ! EDA_HUMAN relationship: location_of CCO:B0058111 ! DAZL_HUMAN relationship: location_of CCO:B0058118 ! DVL3_HUMAN relationship: location_of CCO:B0058123 ! BHMT1_HUMAN relationship: location_of CCO:B0058128 ! NKD2_HUMAN relationship: location_of CCO:B0058130 ! NKD1_HUMAN relationship: location_of CCO:B0058137 ! TRI63_HUMAN relationship: location_of CCO:B0058147 ! RERG_HUMAN relationship: location_of CCO:B0058149 ! ISOC2_HUMAN relationship: location_of CCO:B0058155 ! CIDEC_HUMAN relationship: location_of CCO:B0058166 ! ARL8A_HUMAN relationship: location_of CCO:B0058181 ! BIRC7_HUMAN relationship: location_of CCO:B0058188 ! DDT4L_HUMAN relationship: location_of CCO:B0058209 ! NRBF2_HUMAN relationship: location_of CCO:B0058222 ! MS4A3_HUMAN relationship: location_of CCO:B0058235 ! ITCH_HUMAN relationship: location_of CCO:B0058261 ! PKNX2_HUMAN relationship: location_of CCO:B0058267 ! SNX27_HUMAN relationship: location_of CCO:B0058272 ! HSFY1_HUMAN relationship: location_of CCO:B0058282 ! FGD4_HUMAN relationship: location_of CCO:B0058302 ! ZN396_HUMAN relationship: location_of CCO:B0058311 ! AIFM3_HUMAN relationship: location_of CCO:B0058316 ! NALP3_HUMAN relationship: location_of CCO:B0058325 ! NECA3_HUMAN relationship: location_of CCO:B0058338 ! Z385A_HUMAN relationship: location_of CCO:B0058345 ! QKI_HUMAN relationship: location_of CCO:B0058348 ! FMNL2_HUMAN relationship: location_of CCO:B0058389 ! PKHF1_HUMAN relationship: location_of CCO:B0058409 ! TYBN_HUMAN relationship: location_of CCO:B0058415 ! STAC_HUMAN relationship: location_of CCO:B0058416 ! PFD5_HUMAN relationship: location_of CCO:B0058419 ! EYA1_HUMAN relationship: location_of CCO:B0058429 ! TBX5_HUMAN relationship: location_of CCO:B0058435 ! CHP1_HUMAN relationship: location_of CCO:B0058447 ! ROAA_HUMAN relationship: location_of CCO:B0058457 ! GDIR3_HUMAN relationship: location_of CCO:B0058458 ! MYD88_HUMAN relationship: location_of CCO:B0058462 ! BAG1_HUMAN relationship: location_of CCO:B0058464 ! DUS9_HUMAN relationship: location_of CCO:B0058468 ! DPYL5_HUMAN relationship: location_of CCO:B0058471 ! ARP5L_HUMAN relationship: location_of CCO:B0058473 ! PAIP2_HUMAN relationship: location_of CCO:B0058484 ! NEUL2_HUMAN relationship: location_of CCO:B0058488 ! TXD17_HUMAN relationship: location_of CCO:B0058489 ! PLCD4_HUMAN relationship: location_of CCO:B0058490 ! VPS25_HUMAN relationship: location_of CCO:B0058494 ! AIFM2_HUMAN relationship: location_of CCO:B0058497 ! SLD5_HUMAN relationship: location_of CCO:B0058509 ! CCM2_HUMAN relationship: location_of CCO:B0058514 ! MTA3_HUMAN relationship: location_of CCO:B0058537 ! CAR10_HUMAN relationship: location_of CCO:B0058553 ! SPZ1_HUMAN relationship: location_of CCO:B0058555 ! C1QT2_HUMAN relationship: location_of CCO:B0058559 ! CAR11_HUMAN relationship: location_of CCO:B0058561 ! CLC7A_HUMAN relationship: location_of CCO:B0058569 ! HDAC8_HUMAN relationship: location_of CCO:B0058583 ! TRI54_HUMAN relationship: location_of CCO:B0058584 ! TRI55_HUMAN relationship: location_of CCO:B0058605 ! B2L14_HUMAN relationship: location_of CCO:B0058611 ! ROP1B_HUMAN relationship: location_of CCO:B0058612 ! API5_HUMAN relationship: location_of CCO:B0058613 ! NALP1_HUMAN relationship: location_of CCO:B0058637 ! PEG3_HUMAN relationship: location_of CCO:B0058648 ! PAIP1_HUMAN relationship: location_of CCO:B0058652 ! ARL6_HUMAN relationship: location_of CCO:B0058658 ! ATG10_HUMAN relationship: location_of CCO:B0058662 ! SDCB2_HUMAN relationship: location_of CCO:B0058679 ! CARD9_HUMAN relationship: location_of CCO:B0058684 ! TARA_HUMAN relationship: location_of CCO:B0058686 ! CXXC4_HUMAN relationship: location_of CCO:B0058691 ! CLC4M_HUMAN relationship: location_of CCO:B0058724 ! DUS21_HUMAN relationship: location_of CCO:B0058738 ! ASB8_HUMAN relationship: location_of CCO:B0058750 ! ZN395_HUMAN relationship: location_of CCO:B0058758 ! LN28A_HUMAN relationship: location_of CCO:B0058768 ! SMUF2_HUMAN relationship: location_of CCO:B0058779 ! PIDD_HUMAN relationship: location_of CCO:B0058781 ! RRAGC_HUMAN relationship: location_of CCO:B0058784 ! RHOF_HUMAN relationship: location_of CCO:B0058795 ! NOD2_HUMAN relationship: location_of CCO:B0058818 ! PDE11_HUMAN relationship: location_of CCO:B0058829 ! CD209_HUMAN relationship: location_of CCO:B0058850 ! CENA2_HUMAN relationship: location_of CCO:B0058856 ! NLRC4_HUMAN relationship: location_of CCO:B0058862 ! ISK5_HUMAN relationship: location_of CCO:B0058866 ! A1CF_HUMAN relationship: location_of CCO:B0058885 ! SAR1A_HUMAN relationship: location_of CCO:B0058889 ! ARHG3_HUMAN relationship: location_of CCO:B0058890 ! S2A4R_HUMAN relationship: location_of CCO:B0058894 ! SPTN5_HUMAN relationship: location_of CCO:B0058895 ! SIRT7_HUMAN relationship: location_of CCO:B0058899 ! SH2B1_HUMAN relationship: location_of CCO:B0058900 ! TULP4_HUMAN relationship: location_of CCO:B0058903 ! C42S2_HUMAN relationship: location_of CCO:B0058904 ! C42S1_HUMAN relationship: location_of CCO:B0058906 ! DUS22_HUMAN relationship: location_of CCO:B0058913 ! HOME2_HUMAN relationship: location_of CCO:B0058931 ! RIC8B_HUMAN relationship: location_of CCO:B0058943 ! ASB6_HUMAN relationship: location_of CCO:B0058945 ! NALP2_HUMAN relationship: location_of CCO:B0058946 ! DDT4_HUMAN relationship: location_of CCO:B0058960 ! DACT1_HUMAN relationship: location_of CCO:B0058969 ! KBRS2_HUMAN relationship: location_of CCO:B0058970 ! KBRS1_HUMAN relationship: location_of CCO:B0058994 ! AHSP_HUMAN relationship: location_of CCO:B0058995 ! SPG21_HUMAN relationship: location_of CCO:B0058998 ! TF2L1_HUMAN relationship: location_of CCO:B0059000 ! IF2B1_HUMAN relationship: location_of CCO:B0059012 ! TMOD2_HUMAN relationship: location_of CCO:B0059022 ! Q9NZX6_HUMAN relationship: location_of CCO:B0059023 ! CHMP5_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0059043 ! MDFIC_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059067 ! HSFX1_HUMAN relationship: location_of CCO:B0059071 ! RBX2_HUMAN relationship: location_of CCO:B0059106 ! MALT1_HUMAN relationship: location_of CCO:B0059113 ! MARCO_HUMAN relationship: location_of CCO:B0059144 ! DDX25_HUMAN relationship: location_of CCO:B0059145 ! DPOG2_HUMAN relationship: location_of CCO:B0059165 ! SPB13_HUMAN relationship: location_of CCO:B0059175 ! LEF1_HUMAN relationship: location_of CCO:B0059177 ! DBNL_HUMAN relationship: location_of CCO:B0059188 ! FEM1B_HUMAN relationship: location_of CCO:B0059189 ! AKA11_HUMAN relationship: location_of CCO:B0059191 ! GMEB2_HUMAN relationship: location_of CCO:B0059192 ! PITC1_HUMAN relationship: location_of CCO:B0059227 ! ZMIZ1_HUMAN relationship: location_of CCO:B0059232 ! PAI2B_HUMAN relationship: location_of CCO:B0059251 ! STUB1_HUMAN relationship: location_of CCO:B0059262 ! IQEC3_HUMAN relationship: location_of CCO:B0059263 ! CENG2_HUMAN relationship: location_of CCO:B0059264 ! TRI35_HUMAN relationship: location_of CCO:B0059265 ! PLCL2_HUMAN relationship: location_of CCO:B0059266 ! SMG5_HUMAN relationship: location_of CCO:B0059274 ! MOK_HUMAN relationship: location_of CCO:B0059289 ! PDE10_HUMAN relationship: location_of CCO:B0059290 ! NOD1_HUMAN relationship: location_of CCO:B0059291 ! CLC11_HUMAN relationship: location_of CCO:B0059298 ! INVS_HUMAN relationship: location_of CCO:B0059303 ! CARD8_HUMAN relationship: location_of CCO:B0059314 ! PTN22_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0059334 ! UTP11_HUMAN relationship: location_of CCO:B0059338 ! 3BP1_HUMAN relationship: location_of CCO:B0059361 ! PKHM1_HUMAN relationship: location_of CCO:B0059363 ! GPSM3_HUMAN relationship: location_of CCO:B0059370 ! RIPK3_HUMAN relationship: location_of CCO:B0059410 ! IF2B2_HUMAN relationship: location_of CCO:B0059412 ! STON1_HUMAN relationship: location_of CCO:B0059417 ! DGKB_HUMAN relationship: location_of CCO:B0061986 ! FOX1A_HUMAN relationship: location_of CCO:B0062769 ! EXOC7_HUMAN relationship: location_of CCO:B0062772 ! DD19A_HUMAN relationship: location_of CCO:B0062775 ! TESC_HUMAN relationship: location_of CCO:B0062779 ! PHP14_HUMAN relationship: location_of CCO:B0062780 ! NUP54_HUMAN relationship: location_of CCO:B0062784 ! HEBP2_HUMAN relationship: location_of CCO:B0062792 ! TSNAX_HUMAN relationship: location_of CCO:B0062798 ! BAMBI_HUMAN relationship: location_of CCO:B0062804 ! S100P_HUMAN relationship: location_of CCO:B0062805 ! APBP2_HUMAN relationship: location_of CCO:B0062808 ! SPAT2_HUMAN relationship: location_of CCO:B0062809 ! HOOK2_HUMAN relationship: location_of CCO:B0062812 ! DYL2_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062863 ! ZMY10_HUMAN relationship: location_of CCO:B0062870 ! IPO13_HUMAN relationship: location_of CCO:B0062881 ! TPGS2_HUMAN relationship: location_of CCO:B0062892 ! RO52_HUMAN relationship: location_of CCO:B0062896 ! ZMY19_HUMAN relationship: location_of CCO:B0062900 ! PHIPL_HUMAN relationship: location_of CCO:B0062903 ! UBP2_HUMAN relationship: location_of CCO:B0062913 ! GNPI1_HUMAN relationship: location_of CCO:B0062923 ! ATG12_HUMAN relationship: location_of CCO:B0062931 ! FUZZY_HUMAN relationship: location_of CCO:B0062942 ! CSR2B_HUMAN relationship: location_of CCO:B0062944 ! Q96IH6_HUMAN relationship: location_of CCO:B0062953 ! KIME_HUMAN relationship: location_of CCO:B0062957 ! PHLA1_HUMAN relationship: location_of CCO:B0062961 ! MTHFS_HUMAN relationship: location_of CCO:B0062975 ! WASP_HUMAN relationship: location_of CCO:B0062978 ! HPS1_HUMAN relationship: location_of CCO:B0062979 ! GEMI5_HUMAN relationship: location_of CCO:B0062986 ! VPS4A_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0063000 ! SUMO3_HUMAN relationship: location_of CCO:B0063004 ! RANB9_HUMAN relationship: location_of CCO:B0063005 ! GAN_HUMAN relationship: location_of CCO:B0063008 ! WIPF1_HUMAN relationship: location_of CCO:B0063014 ! AHSA1_HUMAN relationship: location_of CCO:B0063018 ! CDR2_HUMAN relationship: location_of CCO:B0063024 ! COG5_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0063026 ! NCF2_HUMAN relationship: location_of CCO:B0063027 ! ZRAN1_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063034 ! RRAGD_HUMAN relationship: location_of CCO:B0063041 ! SPRR3_HUMAN relationship: location_of CCO:B0063042 ! PTN13_HUMAN relationship: location_of CCO:B0063045 ! SYIC_HUMAN relationship: location_of CCO:B0063057 ! SYVC_HUMAN relationship: location_of CCO:B0063058 ! SYRC_HUMAN relationship: location_of CCO:B0063060 ! SYMC_HUMAN relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0063067 ! CALX_HUMAN relationship: location_of CCO:B0063080 ! TCPA_HUMAN relationship: location_of CCO:B0063083 ! RL3_HUMAN relationship: location_of CCO:B0063086 ! TCPZ_HUMAN relationship: location_of CCO:B0063096 ! HSP74_HUMAN relationship: location_of CCO:B0063112 ! UXT_HUMAN relationship: location_of CCO:B0063118 ! LEG7_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0063128 ! NQO2_HUMAN relationship: location_of CCO:B0063136 ! PDCD2_HUMAN relationship: location_of CCO:B0063142 ! PDRG1_HUMAN relationship: location_of CCO:B0063144 ! AZI2_HUMAN relationship: location_of CCO:B0063160 ! COMT_HUMAN relationship: location_of CCO:B0063186 ! SIAS_HUMAN relationship: location_of CCO:B0063194 ! MOFA1_HUMAN relationship: location_of CCO:B0063195 ! SYHC_HUMAN relationship: location_of CCO:B0063196 ! TRIM2_HUMAN relationship: location_of CCO:B0063207 ! CYTB_HUMAN relationship: location_of CCO:B0063208 ! SNX4_HUMAN relationship: location_of CCO:B0063213 ! HCD2_HUMAN relationship: location_of CCO:B0063236 ! DDX58_HUMAN relationship: location_of CCO:B0063252 ! ASSY_HUMAN relationship: location_of CCO:B0063253 ! NUD14_HUMAN relationship: location_of CCO:B0063255 ! CN37_HUMAN relationship: location_of CCO:B0063258 ! VPS35_HUMAN relationship: location_of CCO:B0063259 ! APBB3_HUMAN relationship: location_of CCO:B0063270 ! DZIP1_HUMAN relationship: location_of CCO:B0063271 ! DZIP3_HUMAN relationship: location_of CCO:B0063274 ! SMYD3_HUMAN relationship: location_of CCO:B0063280 ! MYOTI_HUMAN relationship: location_of CCO:B0063285 ! RABE1_HUMAN relationship: location_of CCO:B0063286 ! LEG3_HUMAN relationship: location_of CCO:B0063294 ! IL1RA_HUMAN relationship: location_of CCO:B0063302 ! PTN2_HUMAN relationship: location_of CCO:B0063315 ! SAPS2_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0063332 ! SYNC_HUMAN relationship: location_of CCO:B0063339 ! EMID2_HUMAN relationship: location_of CCO:B0063349 ! PTN4_HUMAN relationship: location_of CCO:B0063350 ! TRI11_HUMAN relationship: location_of CCO:B0063364 ! ARPC4_HUMAN relationship: location_of CCO:B0063370 ! SRC8_HUMAN relationship: location_of CCO:B0063410 ! MYO15_HUMAN relationship: location_of CCO:B0063415 ! GEMI7_HUMAN relationship: location_of CCO:B0063419 ! PGAM5_HUMAN relationship: location_of CCO:B0063425 ! THOC7_HUMAN relationship: location_of CCO:B0063426 ! NPS3A_HUMAN relationship: location_of CCO:B0063430 ! RIFK_HUMAN relationship: location_of CCO:B0063445 ! BLMH_HUMAN relationship: location_of CCO:B0063453 ! DRG1_HUMAN relationship: location_of CCO:B0063460 ! P34_HUMAN relationship: location_of CCO:B0063467 ! OFD1_HUMAN relationship: location_of CCO:B0063468 ! UBP33_HUMAN relationship: location_of CCO:B0063480 ! PACN1_HUMAN relationship: location_of CCO:B0063483 ! CBR3_HUMAN relationship: location_of CCO:B0063496 ! ACTY_HUMAN relationship: location_of CCO:B0063516 ! M6PBP_HUMAN relationship: location_of CCO:B0063539 ! TRI16_HUMAN relationship: location_of CCO:B0063544 ! ARHG8_HUMAN-Phosphoserine106 relationship: location_of CCO:B0063545 ! ARHGB_HUMAN-Phosphoserine663 relationship: location_of CCO:B0063552 ! ARHGC_HUMAN-Phosphoserine1288 relationship: location_of CCO:B0063567 ! ARHGI_HUMAN-Phosphoserine1124 relationship: location_of CCO:B0063575 ! ARI3A_HUMAN-Phosphoserine81 relationship: location_of CCO:B0063588 ! ARI4B_HUMAN-Phosphoserine1159 relationship: location_of CCO:B0063609 ! ARP19_HUMAN-Phosphoserine104 relationship: location_of CCO:B0063615 ! ARRB1_HUMAN-Phosphothreonine410 relationship: location_of CCO:B0063632 ! ASPP2_HUMAN-Phosphoserine569 relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: location_of CCO:B0063661 ! ATX1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 relationship: location_of CCO:B0063688 ! AXN2_HUMAN-Phosphothreonine640 relationship: location_of CCO:B0063691 ! BACH1_HUMAN-Phosphoserine445 relationship: location_of CCO:B0063711 ! BAIP2_HUMAN-Phosphothreonine296 relationship: location_of CCO:B0063820 ! BCLF1_HUMAN-Phosphoserine177 relationship: location_of CCO:B0063865 ! BCLW_HUMAN-Phosphoserine192 relationship: location_of CCO:B0063925 ! BIRC4_HUMAN-Phosphoserine87 relationship: location_of CCO:B0063939 ! BLNK_HUMAN-Phosphotyrosine178 relationship: location_of CCO:B0063942 ! BMI1_HUMAN-Phosphoserine251 relationship: location_of CCO:B0063945 ! BNC1_HUMAN-Phosphoserine537 relationship: location_of CCO:B0063952 ! BORG2_HUMAN-Phosphoserine89 relationship: location_of CCO:B0063956 ! BORG4_HUMAN-Phosphoserine138 relationship: location_of CCO:B0063964 ! BORG5_HUMAN-Phosphoserine121 relationship: location_of CCO:B0063979 ! BPTF_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0063980 ! BRAF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0063992 ! BRWD1_HUMAN-Phosphoserine696 relationship: location_of CCO:B0064010 ! BTB14_HUMAN-Phosphoserine259 relationship: location_of CCO:B0064015 ! BTK_HUMAN-Phosphotyrosine344 relationship: location_of CCO:B0064017 ! BZW1_HUMAN-Phosphoserine411 relationship: location_of CCO:B0064020 ! C2D1A_HUMAN-Phosphoserine208 relationship: location_of CCO:B0064039 ! CABYR_HUMAN-Phosphoserine362 relationship: location_of CCO:B0064046 ! CACO1_HUMAN-Phosphoserine563 relationship: location_of CCO:B0064066 ! CAPR2_HUMAN-Phosphotyrosine924 relationship: location_of CCO:B0064067 ! CAR14_HUMAN-Phosphoserine544 relationship: location_of CCO:B0064076 ! CASP6_HUMAN-Phosphoserine257 relationship: location_of CCO:B0064079 ! CASP8_HUMAN-Phosphotyrosine334 relationship: location_of CCO:B0064094 ! CBP_HUMAN-Phosphoserine121 relationship: location_of CCO:B0064123 ! CCR2_HUMAN-Sulfotyrosine26 relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0064154 ! CD3D_HUMAN-Phosphotyrosine160 relationship: location_of CCO:B0064164 ! CD3Z_HUMAN-Phosphotyrosine83 relationship: location_of CCO:B0064178 ! CDA7L_HUMAN-Phosphoserine21 relationship: location_of CCO:B0064214 ! CDCA3_HUMAN-Phosphothreonine37 relationship: location_of CCO:B0064224 ! CDCA5_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0064236 ! CDN1C_HUMAN-Phosphoserine268 relationship: location_of CCO:B0064244 ! CDV3_HUMAN-Phosphoserine25 relationship: location_of CCO:B0064259 ! CEND2_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0064268 ! CENG1_HUMAN-Phosphoserine865 relationship: location_of CCO:B0064274 ! CENG3_HUMAN-Phosphoserine336 relationship: location_of CCO:B0064292 ! CENPU_HUMAN-Phosphoserine111 relationship: location_of CCO:B0064344 ! CHD9_HUMAN-Phosphoserine616 relationship: location_of CCO:B0064358 ! CIP4_HUMAN-Phosphoserine335 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0064402 ! CMTA1_HUMAN-Phosphotyrosine117 relationship: location_of CCO:B0064409 ! CND2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0064416 ! CNKR1_HUMAN-Phosphoserine305 relationship: location_of CCO:B0064419 ! CNKR2_HUMAN-Phosphoserine248 relationship: location_of CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0064445 ! CO4A3_HUMAN-Phosphoserine1437 relationship: location_of CCO:B0064446 ! CO4A4_HUMAN-Phosphoserine139 relationship: location_of CCO:B0064449 ! CPEB1_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0064473 ! CRK_HUMAN-Phosphoserine41 relationship: location_of CCO:B0064481 ! CRTC1_HUMAN-Phosphoserine139 relationship: location_of CCO:B0064491 ! CRTC2_HUMAN-Phosphoserine90 relationship: location_of CCO:B0064508 ! CRTC3_HUMAN-Phosphoserine129 relationship: location_of CCO:B0064532 ! CRYAA_HUMAN-Phosphoserine122 relationship: location_of CCO:B0064541 ! CRYAB_HUMAN-Omega-N-methylated arginine50 relationship: location_of CCO:B0064546 ! CSDE1_HUMAN-Phosphothreonine444 relationship: location_of CCO:B0064558 ! CSKI1_HUMAN-Phosphoserine646 relationship: location_of CCO:B0064567 ! CTBP1_HUMAN-Phosphoserine300 relationship: location_of CCO:B0064579 ! CTND2_HUMAN-Phosphoserine415 relationship: location_of CCO:B0064587 ! CTNL1_HUMAN-Phosphoserine538 relationship: location_of CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: location_of CCO:B0064632 ! DAPP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0064669 ! DCX_HUMAN-Phosphoserine196 relationship: location_of CCO:B0064683 ! DD19B_HUMAN-Phosphoserine86 relationship: location_of CCO:B0064684 ! DDAH1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064685 ! DDEF1_HUMAN-Phosphoserine839 relationship: location_of CCO:B0064689 ! DDEF2_HUMAN-Phosphoserine701 relationship: location_of CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: location_of CCO:B0064733 ! DEMA_HUMAN-Phosphoserine156 relationship: location_of CCO:B0064744 ! DFFA_HUMAN-Phosphoserine315 relationship: location_of CCO:B0064748 ! DGCR8_HUMAN-Phosphoserine271 relationship: location_of CCO:B0064753 ! DGKI_HUMAN-Phosphotyrosine1053 relationship: location_of CCO:B0064849 ! DOK3_HUMAN-Phosphotyrosine381 relationship: location_of CCO:B0064869 ! DPYL2_HUMAN-Phosphoserine518 relationship: location_of CCO:B0064874 ! DPYL3_HUMAN-Phosphoserine551 relationship: location_of CCO:B0064879 ! DREB_HUMAN-Phosphothreonine331 relationship: location_of CCO:B0064880 ! DRG2_HUMAN-Phosphoserine199 relationship: location_of CCO:B0064885 ! DSRAD_HUMAN-Phosphothreonine808 relationship: location_of CCO:B0064890 ! DTBP1_HUMAN-Phosphoserine321 relationship: location_of CCO:B0064897 ! DTL_HUMAN-Phosphoserine676 relationship: location_of CCO:B0064903 ! DTX4_HUMAN-Phosphoserine376 relationship: location_of CCO:B0064904 ! DUS10_HUMAN-Phosphoserine4 relationship: location_of CCO:B0064906 ! DUS6_HUMAN-Phosphoserine331 relationship: location_of CCO:B0064911 ! E2AK4_HUMAN-Phosphoserine230 relationship: location_of CCO:B0064937 ! EI2BD_HUMAN-Phosphothreonine86 relationship: location_of CCO:B0064938 ! EI2BE_HUMAN-Phosphoserine525 relationship: location_of CCO:B0064947 ! EIF1_HUMAN-Phosphotyrosine30 relationship: location_of CCO:B0064949 ! EIF2A_HUMAN-Phosphothreonine512 relationship: location_of CCO:B0064954 ! EIF3A_HUMAN-Phosphoserine584 relationship: location_of CCO:B0065043 ! ELP3_HUMAN-Phosphotyrosine202 relationship: location_of CCO:B0065045 ! ELP4_HUMAN-Phosphoserine42 relationship: location_of CCO:B0065055 ! EMAL4_HUMAN-Phosphoserine934 relationship: location_of CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 relationship: location_of CCO:B0065121 ! ERF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065175 ! EVL_HUMAN-Phosphoserine306 relationship: location_of CCO:B0065185 ! EYA3_HUMAN-Phosphoserine266 relationship: location_of CCO:B0065190 ! FABP6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065195 ! 2A5A_HUMAN-Phosphoserine42 relationship: location_of CCO:B0065196 ! 2A5D_HUMAN-Phosphoserine573 relationship: location_of CCO:B0065282 ! ABLM1_HUMAN-Phosphoserine216 relationship: location_of CCO:B0065302 ! ABLM3_HUMAN-Phosphoserine280 relationship: location_of CCO:B0065314 ! ACCN3_HUMAN-Phosphoserine521 relationship: location_of CCO:B0065388 ! ACO11_HUMAN-Phosphoserine367 relationship: location_of CCO:B0065403 ! ADA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065410 ! ADCYA_HUMAN-Phosphothreonine809 relationship: location_of CCO:B0065416 ! ADIPO_HUMAN-5-hydroxylysine65 relationship: location_of CCO:B0065425 ! ADML_HUMAN-Tyrosine amide146 relationship: location_of CCO:B0065435 ! ADPPT_HUMAN-Phosphoserine258 relationship: location_of CCO:B0065511 ! AKA12_HUMAN-Phosphoserine565 relationship: location_of CCO:B0065565 ! AKP13_HUMAN-Phosphoserine1929 relationship: location_of CCO:B0065574 ! AKP8L_HUMAN-Phosphoserine297 relationship: location_of CCO:B0065581 ! AKTS1_HUMAN-Phosphoserine116 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0065642 ! ANR17_HUMAN-Phosphoserine2042 relationship: location_of CCO:B0065655 ! ANXA5_HUMAN-Phosphotyrosine94 relationship: location_of CCO:B0065695 ! AR2BP_HUMAN-Phosphoserine157 relationship: location_of CCO:B0065704 ! ARFG2_HUMAN-Phosphoserine498 relationship: location_of CCO:B0065705 ! ARFG3_HUMAN-Phosphoserine143 relationship: location_of CCO:B0065709 ! ARGAL_HUMAN-Phosphotyrosine131 relationship: location_of CCO:B0065804 ! C43BP_HUMAN-Phosphoserine377 relationship: location_of CCO:B0065818 ! CAPR1_HUMAN-Phosphoserine611 relationship: location_of CCO:B0065820 ! CASC3_HUMAN-Phosphoserine363 relationship: location_of CCO:B0065833 ! CBR1_HUMAN-N6-1-carboxyethyl lysine239 relationship: location_of CCO:B0065840 ! CCD50_HUMAN-Phosphotyrosine144 relationship: location_of CCO:B0065856 ! CHM2B_HUMAN-Phosphoserine199 relationship: location_of CCO:B0065913 ! CUL7_HUMAN-Phosphoserine329 relationship: location_of CCO:B0065953 ! DLDH_HUMAN-N6-acetyllysine127 relationship: location_of CCO:B0065958 ! DOCK2_HUMAN-Phosphoserine1706 relationship: location_of CCO:B0065959 ! DPYL4_HUMAN-Phosphoserine544 relationship: location_of CCO:B0065965 ! E41L3_HUMAN-Phosphothreonine703 relationship: location_of CCO:B0065981 ! EF2_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0066010 ! EPN1_HUMAN-Phosphoserine395 relationship: location_of CCO:B0066020 ! EPN4_HUMAN-Phosphoserine232 relationship: location_of CCO:B0066032 ! EXOC4_HUMAN-Phosphothreonine237 relationship: location_of CCO:B0066035 ! F10A1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0066039 ! F10A4_HUMAN-Phosphoserine71 relationship: location_of CCO:B0066119 ! FANCJ_HUMAN-Phosphothreonine918 relationship: location_of CCO:B0066128 ! FARP1_HUMAN-Phosphoserine896 relationship: location_of CCO:B0066133 ! FARP2_HUMAN-Phosphoserine881 relationship: location_of CCO:B0066134 ! FAS_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0066155 ! FCN2_HUMAN-Hydroxyproline86 relationship: location_of CCO:B0066163 ! FERM2_HUMAN-Phosphoserine181 relationship: location_of CCO:B0066166 ! FER_HUMAN-Phosphoserine434 relationship: location_of CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: location_of CCO:B0066179 ! FGD3_HUMAN-Phosphoserine128 relationship: location_of CCO:B0066183 ! FGD6_HUMAN-Phosphoserine721 relationship: location_of CCO:B0066197 ! FIZ1_HUMAN-Phosphothreonine74 relationship: location_of CCO:B0066198 ! FKBP5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0066213 ! FLNC_HUMAN-Phosphotyrosine2683 relationship: location_of CCO:B0066218 ! FMNL_HUMAN-Phosphoserine184 relationship: location_of CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 relationship: location_of CCO:B0066292 ! FUBP2_HUMAN-Phosphothreonine100 relationship: location_of CCO:B0066301 ! FUMH_HUMAN-Phosphotyrosine491 relationship: location_of CCO:B0066315 ! FUSIP_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0066344 ! GA2L1_HUMAN-Phosphothreonine391 relationship: location_of CCO:B0066357 ! GAB1_HUMAN-Phosphotyrosine406 relationship: location_of CCO:B0066362 ! GALA_HUMAN-Phosphoserine117 relationship: location_of CCO:B0066413 ! GCFC_HUMAN-Phosphoserine557 relationship: location_of CCO:B0066424 ! GCN1L_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0066429 ! GCR_HUMAN-Phosphoserine141 relationship: location_of CCO:B0066435 ! GDIA_HUMAN-Phosphotyrosine339 relationship: location_of CCO:B0066437 ! GDIB_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066440 ! GEMI2_HUMAN-Phosphothreonine48 relationship: location_of CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 relationship: location_of CCO:B0066445 ! GFAP_HUMAN-Phosphothreonine110 relationship: location_of CCO:B0066470 ! GLRX3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0066473 ! GMEB1_HUMAN-Phosphoserine129 relationship: location_of CCO:B0066486 ! GNAI3_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0066490 ! GNAS2_HUMAN-Phosphoserine51 relationship: location_of CCO:B0066503 ! GNMT_HUMAN-N-acetylvaline2 relationship: location_of CCO:B0066505 ! GO45_HUMAN-Phosphoserine353 relationship: location_of CCO:B0066541 ! GPN1_HUMAN-Phosphoserine314 relationship: location_of CCO:B0066552 ! GPSM1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0066556 ! GPSM2_HUMAN-Phosphothreonine479 relationship: location_of CCO:B0066575 ! GPX1_HUMAN-N6-acetyllysine146 relationship: location_of CCO:B0066579 ! GRB10_HUMAN-Phosphoserine150 relationship: location_of CCO:B0066584 ! GRB14_HUMAN-Phosphoserine372 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0066616 ! GRIPE_HUMAN-Phosphoserine860 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0066646 ! GTF2I_HUMAN-Phosphotyrosine248 relationship: location_of CCO:B0066745 ! HABP4_HUMAN-Phosphoserine108 relationship: location_of CCO:B0066767 ! HCFC1_HUMAN-Phosphoserine1205 relationship: location_of CCO:B0066768 ! HCK_HUMAN-Phosphotyrosine209 relationship: location_of CCO:B0066784 ! HDGF_HUMAN-Phosphoserine199 relationship: location_of CCO:B0066799 ! HEXI2_HUMAN-Phosphothreonine32 relationship: location_of CCO:B0066804 ! HIPK2_HUMAN-Phosphotyrosine361 relationship: location_of CCO:B0066805 ! HIPK3_HUMAN-Phosphotyrosine359 relationship: location_of CCO:B0066832 ! HMGN2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0066845 ! HN1L_HUMAN-Phosphoserine97 relationship: location_of CCO:B0066889 ! HOME3_HUMAN-Phosphoserine159 relationship: location_of CCO:B0066894 ! HPS4_HUMAN-Phosphoserine355 relationship: location_of CCO:B0066918 ! HS105_HUMAN-Phosphoserine809 relationship: location_of CCO:B0066921 ! HS74L_HUMAN-Phosphoserine74 relationship: location_of CCO:B0066983 ! IASPP_HUMAN-Phosphoserine119 relationship: location_of CCO:B0067002 ! ICLN_HUMAN-Phosphoserine102 relationship: location_of CCO:B0067036 ! IF4G1_HUMAN-Phosphoserine1210 relationship: location_of CCO:B0067049 ! IF4H_HUMAN-Phosphoserine193 relationship: location_of CCO:B0067057 ! IF6_HUMAN-Phosphoserine243 relationship: location_of CCO:B0067059 ! IFIH1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0067069 ! IKBP1_HUMAN-Phosphoserine242 relationship: location_of CCO:B0067121 ! IPO9_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0067140 ! IQEC1_HUMAN-Phosphoserine515 relationship: location_of CCO:B0067141 ! IQEC2_HUMAN-Phosphoserine82 relationship: location_of CCO:B0067190 ! JADE1_HUMAN-Phosphoserine10 relationship: location_of CCO:B0067219 ! JIP1_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0067250 ! KAISO_HUMAN-Phosphotyrosine442 relationship: location_of CCO:B0067251 ! KALRN_HUMAN-Phosphoserine1750 relationship: location_of CCO:B0067261 ! KC1D_HUMAN-Phosphothreonine347 relationship: location_of CCO:B0067267 ! KCAB2_HUMAN-Phosphotyrosine360 relationship: location_of CCO:B0067285 ! KCIP2_HUMAN-Phosphotyrosine111 relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: location_of CCO:B0067370 ! KKCC2_HUMAN-Phosphoserine133 relationship: location_of CCO:B0067418 ! KPCD_HUMAN-Phosphoserine307 relationship: location_of CCO:B0067435 ! KPYM_HUMAN-Phosphotyrosine83 relationship: location_of CCO:B0067479 ! KS6A5_HUMAN-Phosphoserine752 relationship: location_of CCO:B0067487 ! KS6B1_HUMAN-Phosphoserine441 relationship: location_of CCO:B0067493 ! KS6C1_HUMAN-Phosphoserine640 relationship: location_of CCO:B0067499 ! KSR1_HUMAN-Phosphoserine567 relationship: location_of CCO:B0067505 ! KSYK_HUMAN-Phosphotyrosine323 relationship: location_of CCO:B0067553 ! LAP4_HUMAN-Phosphoserine1223 relationship: location_of CCO:B0067575 ! LASP1_HUMAN-Phosphoserine146 relationship: location_of CCO:B0067579 ! LATS2_HUMAN-Phosphoserine380 relationship: location_of CCO:B0067595 ! LBH_HUMAN-Phosphoserine63 relationship: location_of CCO:B0067601 ! LCP2_HUMAN-Phosphotyrosine23 relationship: location_of CCO:B0067605 ! LDHA_HUMAN-Phosphotyrosine239 relationship: location_of CCO:B0067607 ! LDHB_HUMAN-Phosphotyrosine240 relationship: location_of CCO:B0067657 ! LIMA1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0067677 ! LIPA1_HUMAN-Phosphothreonine230 relationship: location_of CCO:B0067737 ! LMO7_HUMAN-Phosphoserine867 relationship: location_of CCO:B0067775 ! LRCH4_HUMAN-Phosphoserine183 relationship: location_of CCO:B0067781 ! LRRF1_HUMAN-Phosphoserine581 relationship: location_of CCO:B0067785 ! LRSM1_HUMAN-Phosphoserine604 relationship: location_of CCO:B0067803 ! LYST_HUMAN-Phosphoserine2213 relationship: location_of CCO:B0067817 ! M3K2_HUMAN-Phosphoserine331 relationship: location_of CCO:B0067834 ! M4K5_HUMAN-Phosphoserine335 relationship: location_of CCO:B0067835 ! MACF4_HUMAN-Phosphoserine2362 relationship: location_of CCO:B0067845 ! MADD_HUMAN-Phosphoserine921 relationship: location_of CCO:B0067849 ! MAGD1_HUMAN-Phosphotyrosine92 relationship: location_of CCO:B0067850 ! MAGG1_HUMAN-Phosphoserine57 relationship: location_of CCO:B0067988 ! MARE2_HUMAN-Phosphoserine208 relationship: location_of CCO:B0067998 ! MAST2_HUMAN-Phosphoserine74 relationship: location_of CCO:B0068027 ! MBB1A_HUMAN-Phosphothreonine1190 relationship: location_of CCO:B0068043 ! MBIP1_HUMAN-Phosphoserine91 relationship: location_of CCO:B0068044 ! MCA3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068055 ! MCF2_HUMAN-Phosphoserine742 relationship: location_of CCO:B0068058 ! MCL1_HUMAN-Phosphothreonine163 relationship: location_of CCO:B0068111 ! MDHC_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0068170 ! MIB2_HUMAN-Phosphoserine202 relationship: location_of CCO:B0068173 ! MICA1_HUMAN-Phosphoserine876 relationship: location_of CCO:B0068177 ! MIER1_HUMAN-Phosphoserine190 relationship: location_of CCO:B0068219 ! MKNK1_HUMAN-Phosphothreonine250 relationship: location_of CCO:B0068239 ! MLXIP_HUMAN-Phosphoserine27 relationship: location_of CCO:B0068242 ! MLX_HUMAN-Phosphoserine48 relationship: location_of CCO:B0068275 ! MRCKB_HUMAN-Phosphoserine221 relationship: location_of CCO:B0068306 ! MTA1_HUMAN-Phosphoserine386 relationship: location_of CCO:B0068321 ! MTPN_HUMAN-N-acetylcysteine2 relationship: location_of CCO:B0068327 ! MX1_HUMAN-Phosphotyrosine129 relationship: location_of CCO:B0068346 ! MY18A_HUMAN-Phosphoserine2020 relationship: location_of CCO:B0068417 ! MYPT1_HUMAN-Phosphotyrosine911 relationship: location_of CCO:B0068419 ! MYPT2_HUMAN-Phosphoserine947 relationship: location_of CCO:B0068438 ! NAMPT_HUMAN-Phosphotyrosine34 relationship: location_of CCO:B0068440 ! NARG1_HUMAN-Phosphoserine855 relationship: location_of CCO:B0068447 ! NBEA_HUMAN-Phosphoserine1529 relationship: location_of CCO:B0068457 ! NCF1_HUMAN-Phosphoserine304 relationship: location_of CCO:B0068463 ! NCK1_HUMAN-Phosphoserine96 relationship: location_of CCO:B0068465 ! NCK2_HUMAN-Phosphothreonine92 relationship: location_of CCO:B0068476 ! NCOA2_HUMAN-Phosphoserine699 relationship: location_of CCO:B0068532 ! NDRG1_HUMAN-Phosphoserine330 relationship: location_of CCO:B0068542 ! NDRG3_HUMAN-Phosphothreonine332 relationship: location_of CCO:B0068559 ! NED4L_HUMAN-Phosphoserine449 relationship: location_of CCO:B0068587 ! NEXN_HUMAN-Phosphoserine365 relationship: location_of CCO:B0068597 ! NF2IP_HUMAN-Phosphoserine204 relationship: location_of CCO:B0068603 ! NFAC1_HUMAN-Phosphoserine117 relationship: location_of CCO:B0068629 ! NFAC2_HUMAN-Phosphoserine605 relationship: location_of CCO:B0068630 ! NFAC4_HUMAN-Phosphoserine272 relationship: location_of CCO:B0068667 ! NFKB1_HUMAN-Phosphoserine907 relationship: location_of CCO:B0068704 ! NGEF_HUMAN-Phosphotyrosine179 relationship: location_of CCO:B0068738 ! NLK_HUMAN-Phosphothreonine286 relationship: location_of CCO:B0068745 ! NLTP_HUMAN-N6-acetyllysine282 relationship: location_of CCO:B0068796 ! NOSTN_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0068828 ! NRBP_HUMAN-Phosphothreonine441 relationship: location_of CCO:B0068863 ! NSD2_HUMAN-Phosphoserine102 relationship: location_of CCO:B0068929 ! NUMBL_HUMAN-Phosphothreonine279 relationship: location_of CCO:B0068948 ! NUSAP_HUMAN-Phosphothreonine349 relationship: location_of CCO:B0068967 ! OGFR_HUMAN-Phosphoserine484 relationship: location_of CCO:B0068980 ! OPTN_HUMAN-Phosphoserine177 relationship: location_of CCO:B0069002 ! OSTF1_HUMAN-Phosphoserine202 relationship: location_of CCO:B0069006 ! OTU7B_HUMAN-Phosphoserine449 relationship: location_of CCO:B0069015 ! P2RX6_HUMAN-Phosphotyrosine54 relationship: location_of CCO:B0069016 ! P2RX7_HUMAN-Phosphotyrosine343 relationship: location_of CCO:B0069049 ! PACN3_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069062 ! PAIRB_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0069065 ! PAK2_HUMAN-Phosphoserine58 relationship: location_of CCO:B0069080 ! PALMD_HUMAN-Phosphoserine135 relationship: location_of CCO:B0069092 ! PAPOA_HUMAN-Phosphoserine24 relationship: location_of CCO:B0069107 ! PARF_HUMAN-Phosphoserine471 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0069121 ! PASK_HUMAN-Phosphothreonine1161 relationship: location_of CCO:B0069129 ! PAWR_HUMAN-Phosphothreonine229 relationship: location_of CCO:B0069148 ! PBIP1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0069163 ! PDE1B_HUMAN-Phosphoserine466 relationship: location_of CCO:B0069178 ! PDE4D_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069194 ! PDZD1_HUMAN-Phosphoserine514 relationship: location_of CCO:B0069197 ! PEA15_HUMAN-Phosphothreonine6 relationship: location_of CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 relationship: location_of CCO:B0069215 ! PER1_HUMAN-Phosphoserine1100 relationship: location_of CCO:B0069232 ! PER2_HUMAN-Phosphoserine977 relationship: location_of CCO:B0069245 ! PHB2_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0069282 ! PHLP_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069309 ! PIMT_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0069357 ! PKHG5_HUMAN-Phosphoserine959 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0069392 ! PLCD3_HUMAN-Phosphoserine105 relationship: location_of CCO:B0069399 ! PLCH2_HUMAN-Phosphoserine605 relationship: location_of CCO:B0069401 ! PLCL1_HUMAN-Phosphoserine95 relationship: location_of CCO:B0069412 ! PLEK2_HUMAN-Phosphotyrosine333 relationship: location_of CCO:B0069419 ! PLSL_HUMAN-Phosphotyrosine28 relationship: location_of CCO:B0069441 ! PP14A_HUMAN-Phosphothreonine38 relationship: location_of CCO:B0069444 ! PP14B_HUMAN-Phosphoserine32 relationship: location_of CCO:B0069447 ! PP14D_HUMAN-Phosphothreonine58 relationship: location_of CCO:B0069451 ! PP1G_HUMAN-Phosphothreonine307 relationship: location_of CCO:B0069454 ! PP1R8_HUMAN-Phosphotyrosine264 relationship: location_of CCO:B0069463 ! PPR1B_HUMAN-Phosphothreonine75 relationship: location_of CCO:B0069526 ! PRKRA_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069547 ! PRP19_HUMAN-Phosphothreonine342 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069624 ! PUM1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0069628 ! PUM2_HUMAN-Phosphoserine82 relationship: location_of CCO:B0069637 ! PURA_HUMAN-Phosphoserine8 relationship: location_of CCO:B0069649 ! PYR1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0069657 ! QSK_HUMAN-Phosphothreonine163 relationship: location_of CCO:B0069673 ! RAB1B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069678 ! RAB34_HUMAN-Phosphoserine241 relationship: location_of CCO:B0069702 ! RAC2_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0069705 ! RAC3_HUMAN-Cysteine methyl ester189 relationship: location_of CCO:B0069716 ! RAI1_HUMAN-Phosphoserine1431 relationship: location_of CCO:B0069728 ! RANB3_HUMAN-Phosphoserine355 relationship: location_of CCO:B0069732 ! RANG_HUMAN-Phosphothreonine7 relationship: location_of CCO:B0069763 ! RB6I2_HUMAN-Phosphoserine17 relationship: location_of CCO:B0069877 ! REQU_HUMAN-Phosphothreonine176 relationship: location_of CCO:B0069906 ! RGAP1_HUMAN-Phosphoserine600 relationship: location_of CCO:B0069921 ! RGRF2_HUMAN-Phosphoserine737 relationship: location_of CCO:B0069929 ! RHG01_HUMAN-Phosphotyrosine65 relationship: location_of CCO:B0069930 ! RHG04_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0069933 ! RHG05_HUMAN-Phosphoserine1124 relationship: location_of CCO:B0069944 ! RHG06_HUMAN-Phosphoserine754 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0070012 ! RHOH_HUMAN-Cysteine methyl ester188 relationship: location_of CCO:B0070014 ! RHOQ_HUMAN-Cysteine methyl ester202 relationship: location_of CCO:B0070015 ! RHPN2_HUMAN-Nitrated tyrosine258 relationship: location_of CCO:B0070017 ! RICH2_HUMAN-Phosphoserine514 relationship: location_of CCO:B0070054 ! RIN2_HUMAN-Phosphothreonine509 relationship: location_of CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 relationship: location_of CCO:B0070096 ! RMP_HUMAN-Phosphothreonine242 relationship: location_of CCO:B0070107 ! RNF14_HUMAN-Phosphoserine348 relationship: location_of CCO:B0070116 ! RNPS1_HUMAN-Phosphoserine287 relationship: location_of CCO:B0070132 ! ROCK1_HUMAN-Phosphothreonine1180 relationship: location_of CCO:B0070161 ! RPE65_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070172 ! RPGF6_HUMAN-Phosphothreonine1507 relationship: location_of CCO:B0070190 ! RREB1_HUMAN-Phosphothreonine1315 relationship: location_of CCO:B0070270 ! RYBP_HUMAN-Phosphoserine130 relationship: location_of CCO:B0070274 ! S10AB_HUMAN-Phosphothreonine10 relationship: location_of CCO:B0070308 ! SAFB2_HUMAN-Phosphoserine331 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070371 ! SEP10_HUMAN-Phosphoserine451 relationship: location_of CCO:B0070459 ! SH22A_HUMAN-Phosphoserine296 relationship: location_of CCO:B0070469 ! SH2B2_HUMAN-Phosphotyrosine629 relationship: location_of CCO:B0070472 ! SH2D3_HUMAN-Phosphotyrosine283 relationship: location_of CCO:B0070479 ! SHAN2_HUMAN-Phosphoserine1113 relationship: location_of CCO:B0070486 ! SHAN3_HUMAN-Phosphoserine783 relationship: location_of CCO:B0070494 ! SHB_HUMAN-Phosphoserine314 relationship: location_of CCO:B0070505 ! SHIP1_HUMAN-Phosphotyrosine944 relationship: location_of CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 relationship: location_of CCO:B0070563 ! SIVA_HUMAN-Phosphotyrosine34 relationship: location_of CCO:B0070565 ! SKAP1_HUMAN-Phosphotyrosine142 relationship: location_of CCO:B0070574 ! SKAP2_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0070598 ! SMAD2_HUMAN-Phosphoserine255 relationship: location_of CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 relationship: location_of CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 relationship: location_of CCO:B0070613 ! SMBP2_HUMAN-Phosphoserine656 relationship: location_of CCO:B0070645 ! SMG7_HUMAN-Phosphoserine781 relationship: location_of CCO:B0070647 ! SMN_HUMAN-Phosphothreonine25 relationship: location_of CCO:B0070678 ! SNCAP_HUMAN-Phosphothreonine387 relationship: location_of CCO:B0070680 ! SND1_HUMAN-Phosphothreonine429 relationship: location_of CCO:B0070697 ! SNTA1_HUMAN-Phosphoserine189 relationship: location_of CCO:B0070704 ! SNTB1_HUMAN-Phosphoserine389 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: location_of CCO:B0070716 ! SNX17_HUMAN-Phosphoserine437 relationship: location_of CCO:B0070720 ! SOLO_HUMAN-Phosphoserine931 relationship: location_of CCO:B0070790 ! SPB4_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0070797 ! SPF30_HUMAN-Phosphoserine201 relationship: location_of CCO:B0070798 ! SPHK1_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0070821 ! SPTA2_HUMAN-Phosphoserine1217 relationship: location_of CCO:B0070827 ! SPTB1_HUMAN-Phosphoserine2117 relationship: location_of CCO:B0070838 ! SPTN2_HUMAN-Phosphothreonine2354 relationship: location_of CCO:B0070840 ! SPTN4_HUMAN-Phosphothreonine2112 relationship: location_of CCO:B0070843 ! SPY4_HUMAN-Phosphoserine125 relationship: location_of CCO:B0070846 ! SQSTM_HUMAN-Phosphoserine170 relationship: location_of CCO:B0070862 ! SRA1_HUMAN-Phosphothreonine68 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0070912 ! SRGEF_HUMAN-Phosphoserine427 relationship: location_of CCO:B0070926 ! SRPK1_HUMAN-Phosphoserine309 relationship: location_of CCO:B0070946 ! STA5A_HUMAN-Phosphoserine193 relationship: location_of CCO:B0070950 ! STABP_HUMAN-Phosphoserine245 relationship: location_of CCO:B0070960 ! STAM2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0070963 ! STAP1_HUMAN-Phosphotyrosine168 relationship: location_of CCO:B0070966 ! STAT3_HUMAN-Phosphothreonine714 relationship: location_of CCO:B0070967 ! STAT4_HUMAN-Phosphotyrosine693 relationship: location_of CCO:B0070973 ! STIL_HUMAN-Phosphoserine753 relationship: location_of CCO:B0070975 ! STK3_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0070979 ! STRN4_HUMAN-Phosphoserine276 relationship: location_of CCO:B0070992 ! STXB1_HUMAN-Phosphothreonine346 relationship: location_of CCO:B0070996 ! SUFU_HUMAN-Phosphoserine481 relationship: location_of CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: location_of CCO:B0071022 ! SYAC_HUMAN-Phosphothreonine578 relationship: location_of CCO:B0071036 ! SYEP_HUMAN-Phosphoserine891 relationship: location_of CCO:B0071042 ! SYLC_HUMAN-Phosphothreonine721 relationship: location_of CCO:B0071075 ! TAB2_HUMAN-Phosphoserine372 relationship: location_of CCO:B0071119 ! TANK_HUMAN-Phosphoserine129 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0071208 ! TBB2C_HUMAN-Phosphoserine322 relationship: location_of CCO:B0071291 ! TCPQ_HUMAN-Phosphoserine23 relationship: location_of CCO:B0071323 ! TEC_HUMAN-Phosphotyrosine519 relationship: location_of CCO:B0071372 ! TFG_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0071434 ! TMOD3_HUMAN-Phosphoserine25 relationship: location_of CCO:B0071438 ! TNAP3_HUMAN-Phosphoserine575 relationship: location_of CCO:B0071447 ! TOM1_HUMAN-Phosphoserine176 relationship: location_of CCO:B0071476 ! TPD53_HUMAN-Phosphoserine149 relationship: location_of CCO:B0071477 ! TPM1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0071480 ! TPM2_HUMAN-Phosphoserine283 relationship: location_of CCO:B0071481 ! TPM3_HUMAN-Phosphotyrosine162 relationship: location_of CCO:B0071526 ! TRAF4_HUMAN-Phosphoserine426 relationship: location_of CCO:B0071529 ! TRAIP_HUMAN-Phosphoserine259 relationship: location_of CCO:B0071551 ! TRI29_HUMAN-Phosphoserine21 relationship: location_of CCO:B0071561 ! TRI41_HUMAN-Phosphoserine447 relationship: location_of CCO:B0071591 ! TRXR1_HUMAN-Phosphotyrosine163 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: location_of CCO:B0071623 ! TTF2_HUMAN-Phosphoserine396 relationship: location_of CCO:B0071632 ! TXLNA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0071661 ! UACA_HUMAN-Phosphotyrosine723 relationship: location_of CCO:B0071678 ! UBP16_HUMAN-Phosphoserine415 relationship: location_of CCO:B0071730 ! ULK1_HUMAN-Phosphothreonine625 relationship: location_of CCO:B0071732 ! UN13A_HUMAN-Phosphoserine245 relationship: location_of CCO:B0071733 ! UN13B_HUMAN-Phosphothreonine605 relationship: location_of CCO:B0071778 ! VASP_HUMAN-Phosphotyrosine39 relationship: location_of CCO:B0071789 ! VAV2_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0071803 ! VINEX_HUMAN-Phosphothreonine529 relationship: location_of CCO:B0071823 ! WASF2_HUMAN-Phosphoserine482 relationship: location_of CCO:B0071833 ! WBS14_HUMAN-Phosphothreonine509 relationship: location_of CCO:B0071860 ! WNK1_HUMAN-Phosphoserine2121 relationship: location_of CCO:B0071885 ! WWTR1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0071891 ! XPO7_HUMAN-Phosphotyrosine58 relationship: location_of CCO:B0071930 ! YYAP1_HUMAN-Phosphoserine724 relationship: location_of CCO:B0071950 ! ZAP70_HUMAN-Phosphotyrosine315 relationship: location_of CCO:B0072026 ! ZFY16_HUMAN-Phosphoserine815 relationship: location_of CCO:B0072196 ! ZN638_HUMAN-Phosphoserine605 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000325 name: mitochondrion namespace: cellular_component def: "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "mitochondria" EXACT [] xref: GO:0005739 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0001398 ! TRIA1_HUMAN relationship: location_of CCO:B0001569 ! SHC1_HUMAN relationship: location_of CCO:B0001591 ! PHB_HUMAN relationship: location_of CCO:B0001600 ! VHL_HUMAN relationship: location_of CCO:B0001677 ! MTCPA_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0001723 ! BAX_HUMAN relationship: location_of CCO:B0001952 ! RM41_HUMAN relationship: location_of CCO:B0002030 ! TBRG4_HUMAN relationship: location_of CCO:B0002132 ! Q9H315_HUMAN relationship: location_of CCO:B0002181 ! WWOX_HUMAN relationship: location_of CCO:B0002253 ! STA13_HUMAN relationship: location_of CCO:B0005175 ! BAD_HUMAN relationship: location_of CCO:B0005206 ! NDKM_HUMAN relationship: location_of CCO:B0005254 ! K1683_HUMAN relationship: location_of CCO:B0005422 ! BID_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0005818 ! DNJA3_HUMAN relationship: location_of CCO:B0005828 ! GRP75_HUMAN relationship: location_of CCO:B0005848 ! BBC3_HUMAN relationship: location_of CCO:B0005901 ! BCLX_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0006089 ! COX17_HUMAN relationship: location_of CCO:B0006095 ! RT12_HUMAN relationship: location_of CCO:B0006116 ! TOM20_HUMAN relationship: location_of CCO:B0006131 ! KCRS_HUMAN relationship: location_of CCO:B0006185 ! ODO2_HUMAN relationship: location_of CCO:B0006189 ! ETHE1_HUMAN relationship: location_of CCO:B0006201 ! IMMT_HUMAN relationship: location_of CCO:B0006208 ! RT06_HUMAN relationship: location_of CCO:B0006209 ! MYCBP_HUMAN relationship: location_of CCO:B0006248 ! RM20_HUMAN relationship: location_of CCO:B0006288 ! RT26_HUMAN relationship: location_of CCO:B0006289 ! NDUB8_HUMAN relationship: location_of CCO:B0006298 ! NIPS1_HUMAN relationship: location_of CCO:B0006340 ! APR_HUMAN relationship: location_of CCO:B0006345 ! CATB_HUMAN relationship: location_of CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0010462 ! ADT2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011197 ! CH60_HUMAN-Phosphoserine70 relationship: location_of CCO:B0011337 ! COX6C_HUMAN-N6-acetyllysine60 relationship: location_of CCO:B0011946 ! GLYAT_HUMAN-N6-acetyllysine20 relationship: location_of CCO:B0012274 ! HSP71_HUMAN-Phosphotyrosine611 relationship: location_of CCO:B0012627 ! KPCA_HUMAN-Phosphoserine657 relationship: location_of CCO:B0012714 ! M2OM_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012956 ! MK12_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0012980 ! MPCP_HUMAN-N6-acetyllysine99 relationship: location_of CCO:B0013032 ! MTFR1_HUMAN-Phosphoserine33 relationship: location_of CCO:B0013046 ! MTUS1_HUMAN-Phosphoserine1264 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014175 ! SPG7_HUMAN-Nitrated tyrosine505 relationship: location_of CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0014603 ! VDAC2_HUMAN-Phosphoserine115 relationship: location_of CCO:B0014607 ! VDAC3_HUMAN-N6-acetyllysine61 relationship: location_of CCO:B0014938 ! AIFM1_HUMAN relationship: location_of CCO:B0016000 ! MTERF_HUMAN relationship: location_of CCO:B0016003 ! MTER3_HUMAN relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0016807 ! PDK1_HUMAN relationship: location_of CCO:B0016810 ! PDK3_HUMAN relationship: location_of CCO:B0016811 ! PDK2_HUMAN relationship: location_of CCO:B0017165 ! DPOG1_HUMAN relationship: location_of CCO:B0017622 ! 3BP5_HUMAN relationship: location_of CCO:B0021658 ! NDUS6_HUMAN relationship: location_of CCO:B0023090 ! TMLH_HUMAN relationship: location_of CCO:B0024704 ! PPA6_HUMAN relationship: location_of CCO:B0024782 ! TOP1M_HUMAN relationship: location_of CCO:B0025098 ! LETM1_HUMAN relationship: location_of CCO:B0025227 ! EMI5_HUMAN relationship: location_of CCO:B0025951 ! LRP5_HUMAN relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: location_of CCO:B0032300 ! FRDA_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0033823 ! BACH_HUMAN relationship: location_of CCO:B0034526 ! AFG32_HUMAN-N6-acetyllysine308 relationship: location_of CCO:B0034583 ! B2L13_HUMAN-Phosphoserine420 relationship: location_of CCO:B0035014 ! KCRB_HUMAN-Phosphoserine164 relationship: location_of CCO:B0035188 ! MDHM_HUMAN-Phosphotyrosine56 relationship: location_of CCO:B0035356 ! PDK4_HUMAN-Phosphohistidine127 relationship: location_of CCO:B0035672 ! SODM_HUMAN-N6-acetyllysine68 relationship: location_of CCO:B0039862 ! KLK6_HUMAN relationship: location_of CCO:B0040310 ! RF1M_HUMAN relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041258 ! XAF1_HUMAN relationship: location_of CCO:B0043446 ! RM10_HUMAN relationship: location_of CCO:B0043817 ! NGX6_HUMAN relationship: location_of CCO:B0043863 ! KBP_HUMAN relationship: location_of CCO:B0050997 ! MFN2_HUMAN relationship: location_of CCO:B0051370 ! FIBP_HUMAN relationship: location_of CCO:B0052306 ! C1TC_HUMAN-Phosphothreonine786 relationship: location_of CCO:B0052833 ! TGM2_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0053804 ! A6NE74_HUMAN relationship: location_of CCO:B0054290 ! KITM_HUMAN relationship: location_of CCO:B0054315 ! O00366_HUMAN relationship: location_of CCO:B0054454 ! NDUS4_HUMAN relationship: location_of CCO:B0054465 ! PROD_HUMAN relationship: location_of CCO:B0054493 ! AKA10_HUMAN relationship: location_of CCO:B0054520 ! MCAT_HUMAN relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: location_of CCO:B0054566 ! CIDEA_HUMAN relationship: location_of CCO:B0054644 ! NDUS3_HUMAN relationship: location_of CCO:B0054797 ! DCMC_HUMAN relationship: location_of CCO:B0054820 ! PX11B_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0054951 ! IFI6_HUMAN relationship: location_of CCO:B0054953 ! RB40L_HUMAN relationship: location_of CCO:B0055023 ! HCLS1_HUMAN relationship: location_of CCO:B0055167 ! CPT2_HUMAN relationship: location_of CCO:B0055216 ! PRDX3_HUMAN relationship: location_of CCO:B0055220 ! TSPO_HUMAN relationship: location_of CCO:B0055266 ! DUT_HUMAN relationship: location_of CCO:B0055464 ! RT29_HUMAN relationship: location_of CCO:B0055501 ! RM12_HUMAN relationship: location_of CCO:B0055558 ! SYJ2B_HUMAN relationship: location_of CCO:B0055648 ! ARGI2_HUMAN relationship: location_of CCO:B0055678 ! TFAM_HUMAN relationship: location_of CCO:B0055871 ! RM28_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055978 ! FKBP8_HUMAN relationship: location_of CCO:B0056142 ! CRY1_HUMAN relationship: location_of CCO:B0056362 ! AGK_HUMAN relationship: location_of CCO:B0056499 ! Q5JXL8_HUMAN relationship: location_of CCO:B0056967 ! Q6W3F3_HUMAN relationship: location_of CCO:B0057344 ! HUNIN_HUMAN relationship: location_of CCO:B0057354 ! Q8IW90_HUMAN relationship: location_of CCO:B0057377 ! MIRO2_HUMAN relationship: location_of CCO:B0057378 ! MIRO1_HUMAN relationship: location_of CCO:B0057995 ! TFB1M_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058059 ! CPT1B_HUMAN relationship: location_of CCO:B0058142 ! MUL1_HUMAN relationship: location_of CCO:B0058149 ! ISOC2_HUMAN relationship: location_of CCO:B0058311 ! AIFM3_HUMAN relationship: location_of CCO:B0058382 ! PEO1_HUMAN relationship: location_of CCO:B0058494 ! AIFM2_HUMAN relationship: location_of CCO:B0058560 ! PINK1_HUMAN relationship: location_of CCO:B0058687 ! IF3M_HUMAN relationship: location_of CCO:B0058728 ! TFB2M_HUMAN relationship: location_of CCO:B0058785 ! DEFM_HUMAN relationship: location_of CCO:B0058844 ! NT5M_HUMAN relationship: location_of CCO:B0058884 ! DBLOH_HUMAN relationship: location_of CCO:B0058888 ! ASAH2_HUMAN relationship: location_of CCO:B0058924 ! SIRT3_HUMAN relationship: location_of CCO:B0059001 ! MTCH1_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0059077 ! PEMT_HUMAN relationship: location_of CCO:B0059145 ! DPOG2_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059203 ! ACAD8_HUMAN relationship: location_of CCO:B0059269 ! TRAK1_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0062803 ! APEX2_HUMAN relationship: location_of CCO:B0062893 ! SAM50_HUMAN relationship: location_of CCO:B0062899 ! GCSH_HUMAN relationship: location_of CCO:B0062930 ! RT18B_HUMAN relationship: location_of CCO:B0062956 ! ODPX_HUMAN relationship: location_of CCO:B0062990 ! SFXN3_HUMAN relationship: location_of CCO:B0063040 ! RPOM_HUMAN relationship: location_of CCO:B0063057 ! SYVC_HUMAN relationship: location_of CCO:B0063062 ! SFXN1_HUMAN relationship: location_of CCO:B0063070 ! IDH3A_HUMAN relationship: location_of CCO:B0063102 ! SCO2_HUMAN relationship: location_of CCO:B0063211 ! SQRD_HUMAN relationship: location_of CCO:B0063213 ! HCD2_HUMAN relationship: location_of CCO:B0063217 ! M11D1_HUMAN relationship: location_of CCO:B0063220 ! IDH3B_HUMAN relationship: location_of CCO:B0063238 ! ODBB_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0063251 ! TIM44_HUMAN relationship: location_of CCO:B0063290 ! XPP3_HUMAN relationship: location_of CCO:B0063342 ! ATPF2_HUMAN relationship: location_of CCO:B0063358 ! ADT1_HUMAN relationship: location_of CCO:B0063361 ! GLYM_HUMAN relationship: location_of CCO:B0063375 ! ALDH2_HUMAN relationship: location_of CCO:B0063380 ! PDIP2_HUMAN relationship: location_of CCO:B0063385 ! RM44_HUMAN relationship: location_of CCO:B0063423 ! NDUB9_HUMAN relationship: location_of CCO:B0063424 ! NDUV2_HUMAN relationship: location_of CCO:B0063466 ! RT31_HUMAN relationship: location_of CCO:B0063495 ! S2538_HUMAN relationship: location_of CCO:B0063498 ! NDUS7_HUMAN relationship: location_of CCO:B0063503 ! QCR8_HUMAN relationship: location_of CCO:B0063510 ! PTCD3_HUMAN relationship: location_of CCO:B0063523 ! RM38_HUMAN relationship: location_of CCO:B0063534 ! SPYA_HUMAN relationship: location_of CCO:B0063791 ! BCKD_HUMAN-Phosphoserine52 relationship: location_of CCO:B0063865 ! BCLW_HUMAN-Phosphoserine192 relationship: location_of CCO:B0064066 ! CAPR2_HUMAN-Phosphotyrosine924 relationship: location_of CCO:B0064079 ! CASP8_HUMAN-Phosphotyrosine334 relationship: location_of CCO:B0064302 ! CH10_HUMAN-Phosphotyrosine88 relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0064756 ! DHE3_HUMAN-N6-acetyllysine84 relationship: location_of CCO:B0064869 ! DPYL2_HUMAN-Phosphoserine518 relationship: location_of CCO:B0065163 ! ESR2_HUMAN-Phosphoserine87 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0065450 ! ADT3_HUMAN-N-acetylthreonine2 relationship: location_of CCO:B0065695 ! AR2BP_HUMAN-Phosphoserine157 relationship: location_of CCO:B0065758 ! ATPK_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065764 ! ATPO_HUMAN-N6-acetyllysine176 relationship: location_of CCO:B0065801 ! C1QBP_HUMAN-Phosphoserine201 relationship: location_of CCO:B0065905 ! CPSM_HUMAN-N6-acetyllysine841 relationship: location_of CCO:B0065947 ! DHB4_HUMAN-Phosphoserine309 relationship: location_of CCO:B0065953 ! DLDH_HUMAN-N6-acetyllysine127 relationship: location_of CCO:B0065975 ! ECH1_HUMAN-Phosphoserine30 relationship: location_of CCO:B0065977 ! ECHA_HUMAN-N6-acetyllysine728 relationship: location_of CCO:B0065980 ! ECHB_HUMAN-N6-acetyllysine348 relationship: location_of CCO:B0066301 ! FUMH_HUMAN-Phosphotyrosine491 relationship: location_of CCO:B0066302 ! FUND2_HUMAN-Phosphoserine151 relationship: location_of CCO:B0066469 ! GLRX2_HUMAN-cysteine77 relationship: location_of CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 relationship: location_of CCO:B0066575 ! GPX1_HUMAN-N6-acetyllysine146 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066831 ! HMGCL_HUMAN-N6-acetyllysine48 relationship: location_of CCO:B0066926 ! HSP72_HUMAN-Phosphotyrosine108 relationship: location_of CCO:B0066966 ! HXK1_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0067010 ! IF2M_HUMAN-Phosphothreonine688 relationship: location_of CCO:B0068019 ! MAVS_HUMAN-Phosphothreonine398 relationship: location_of CCO:B0068058 ! MCL1_HUMAN-Phosphothreonine163 relationship: location_of CCO:B0068239 ! MLXIP_HUMAN-Phosphoserine27 relationship: location_of CCO:B0068547 ! NDUA6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068548 ! NDUA7_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068554 ! NDUV1_HUMAN-N6-acetyllysine81 relationship: location_of CCO:B0068745 ! NLTP_HUMAN-N6-acetyllysine282 relationship: location_of CCO:B0068953 ! ODBA_HUMAN-Phosphoserine337 relationship: location_of CCO:B0069077 ! PAK7_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0069206 ! PECR_HUMAN-Phosphotyrosine179 relationship: location_of CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 relationship: location_of CCO:B0069245 ! PHB2_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069451 ! PP1G_HUMAN-Phosphothreonine307 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069676 ! RAB32_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0070251 ! RT09_HUMAN-Phosphotyrosine262 relationship: location_of CCO:B0070578 ! SLIRP_HUMAN-Phosphoserine102 relationship: location_of CCO:B0070676 ! SNAG_HUMAN-Phosphoserine284 relationship: location_of CCO:B0070938 ! SSB_HUMAN-Phosphoserine79 relationship: location_of CCO:B0072012 ! ZFHX3_HUMAN-Phosphoserine1180 [Term] id: CCO:C0000326 name: mitochondrial envelope namespace: cellular_component def: "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space." [GOC:ai, GOC:pz] subset: goslim_candida subset: goslim_yeast xref: GO:0005740 is_a: CCO:C0001360 ! organelle envelope is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0005421 ! BIK_HUMAN relationship: location_of CCO:B0006116 ! TOM20_HUMAN relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0054161 ! B0AZS9_HUMAN relationship: location_of CCO:B0054566 ! CIDEA_HUMAN relationship: location_of CCO:B0055978 ! FKBP8_HUMAN relationship: location_of CCO:B0056497 ! Q5JW63_HUMAN relationship: location_of CCO:B0058704 ! Q9H3K3_HUMAN relationship: location_of CCO:B0058850 ! CENA2_HUMAN relationship: location_of CCO:B0065980 ! ECHB_HUMAN-N6-acetyllysine348 [Term] id: CCO:C0000327 name: mitochondrial outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope." [GOC:ai] xref: GO:0005741 is_a: CCO:C0001359 ! mitochondrial membrane is_a: CCO:C0001361 ! organelle outer membrane relationship: location_of CCO:B0001723 ! BAX_HUMAN relationship: location_of CCO:B0005175 ! BAD_HUMAN relationship: location_of CCO:B0005422 ! BID_HUMAN relationship: location_of CCO:B0005848 ! BBC3_HUMAN relationship: location_of CCO:B0005901 ! BCLX_HUMAN relationship: location_of CCO:B0006116 ! TOM20_HUMAN relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0013681 ! RAF1_HUMAN-Phosphoserine259 relationship: location_of CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0014603 ! VDAC2_HUMAN-Phosphoserine115 relationship: location_of CCO:B0014607 ! VDAC3_HUMAN-N6-acetyllysine61 relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0050997 ! MFN2_HUMAN relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: location_of CCO:B0055220 ! TSPO_HUMAN relationship: location_of CCO:B0055558 ! SYJ2B_HUMAN relationship: location_of CCO:B0055948 ! Q13850_HUMAN relationship: location_of CCO:B0057377 ! MIRO2_HUMAN relationship: location_of CCO:B0057378 ! MIRO1_HUMAN relationship: location_of CCO:B0058059 ! CPT1B_HUMAN relationship: location_of CCO:B0058142 ! MUL1_HUMAN relationship: location_of CCO:B0058494 ! AIFM2_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0062893 ! SAM50_HUMAN relationship: location_of CCO:B0063924 ! BIM_HUMAN-Phosphoserine77 relationship: location_of CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0066966 ! HXK1_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0068019 ! MAVS_HUMAN-Phosphothreonine398 relationship: location_of CCO:B0068058 ! MCL1_HUMAN-Phosphothreonine163 relationship: location_of CCO:B0068239 ! MLXIP_HUMAN-Phosphoserine27 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069451 ! PP1G_HUMAN-Phosphothreonine307 [Term] id: CCO:C0000328 name: mitochondrial outer membrane translocase complex namespace: cellular_component def: "A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments." [PMID:12581629] synonym: "GIP complex" NARROW [] synonym: "TOM complex" NARROW [] xref: GO:0005742 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: location_of CCO:B0006116 ! TOM20_HUMAN relationship: part_of CCO:C0000327 ! mitochondrial outer membrane [Term] id: CCO:C0000329 name: mitochondrial inner membrane namespace: cellular_component def: "The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae." [GOC:ai] xref: GO:0005743 is_a: CCO:C0000897 ! organelle inner membrane is_a: CCO:C0001359 ! mitochondrial membrane relationship: location_of CCO:B0001591 ! PHB_HUMAN relationship: location_of CCO:B0005206 ! NDKM_HUMAN relationship: location_of CCO:B0006131 ! KCRS_HUMAN relationship: location_of CCO:B0006201 ! IMMT_HUMAN relationship: location_of CCO:B0006289 ! NDUB8_HUMAN relationship: location_of CCO:B0006298 ! NIPS1_HUMAN relationship: location_of CCO:B0010462 ! ADT2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: location_of CCO:B0011197 ! CH60_HUMAN-Phosphoserine70 relationship: location_of CCO:B0011337 ! COX6C_HUMAN-N6-acetyllysine60 relationship: location_of CCO:B0012714 ! M2OM_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012980 ! MPCP_HUMAN-N6-acetyllysine99 relationship: location_of CCO:B0017165 ! DPOG1_HUMAN relationship: location_of CCO:B0021658 ! NDUS6_HUMAN relationship: location_of CCO:B0025098 ! LETM1_HUMAN relationship: location_of CCO:B0026813 ! CD014_HUMAN relationship: location_of CCO:B0034526 ! AFG32_HUMAN-N6-acetyllysine308 relationship: location_of CCO:B0035188 ! MDHM_HUMAN-Phosphotyrosine56 relationship: location_of CCO:B0035356 ! PDK4_HUMAN-Phosphohistidine127 relationship: location_of CCO:B0035672 ! SODM_HUMAN-N6-acetyllysine68 relationship: location_of CCO:B0054290 ! KITM_HUMAN relationship: location_of CCO:B0054454 ! NDUS4_HUMAN relationship: location_of CCO:B0054520 ! MCAT_HUMAN relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: location_of CCO:B0054644 ! NDUS3_HUMAN relationship: location_of CCO:B0055167 ! CPT2_HUMAN relationship: location_of CCO:B0057377 ! MIRO2_HUMAN relationship: location_of CCO:B0058311 ! AIFM3_HUMAN relationship: location_of CCO:B0059001 ! MTCH1_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0062847 ! DHRS1_HUMAN relationship: location_of CCO:B0062893 ! SAM50_HUMAN relationship: location_of CCO:B0063062 ! SFXN1_HUMAN relationship: location_of CCO:B0063102 ! SCO2_HUMAN relationship: location_of CCO:B0063211 ! SQRD_HUMAN relationship: location_of CCO:B0063251 ! TIM44_HUMAN relationship: location_of CCO:B0063358 ! ADT1_HUMAN relationship: location_of CCO:B0063361 ! GLYM_HUMAN relationship: location_of CCO:B0063423 ! NDUB9_HUMAN relationship: location_of CCO:B0063424 ! NDUV2_HUMAN relationship: location_of CCO:B0063495 ! S2538_HUMAN relationship: location_of CCO:B0063503 ! QCR8_HUMAN relationship: location_of CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065450 ! ADT3_HUMAN-N-acetylthreonine2 relationship: location_of CCO:B0065758 ! ATPK_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065764 ! ATPO_HUMAN-N6-acetyllysine176 relationship: location_of CCO:B0065977 ! ECHA_HUMAN-N6-acetyllysine728 relationship: location_of CCO:B0065980 ! ECHB_HUMAN-N6-acetyllysine348 relationship: location_of CCO:B0068547 ! NDUA6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068548 ! NDUA7_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068554 ! NDUV1_HUMAN-N6-acetyllysine81 relationship: location_of CCO:B0069245 ! PHB2_HUMAN-Phosphotyrosine128 [Term] id: CCO:C0000330 name: mitochondrial inner membrane presequence translocase complex namespace: cellular_component def: "The protein transport machinery of the mitochondrial inner membrane that contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor." [EC:3.6.3.51, PMID:8851659] comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. subset: goslim_pir synonym: "mitochondrial inner membrane pre-sequence translocase complex" EXACT [] synonym: "mitochondrial inner membrane translocase complex" EXACT [] synonym: "Tim23 complex" NARROW [] xref: GO:0005744 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: location_of CCO:B0063251 ! TIM44_HUMAN relationship: location_of CCO:B0065450 ! ADT3_HUMAN-N-acetylthreonine2 relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0000331 name: m-AAA complex namespace: cellular_component def: "Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria." [PMID:12417197] xref: GO:0005745 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0000332 name: mitochondrial respiratory chain namespace: cellular_component def: "The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. Complexes I, III and IV can transport protons if embedded in an oriented membrane, such as an intact mitochondrial inner membrane." [GOC:curators, ISBN:0198547684] synonym: "mitochondrial electron transport chain" EXACT [] xref: GO:0005746 is_a: CCO:C0001874 ! mitochondrial membrane part relationship: location_of CCO:B0006289 ! NDUB8_HUMAN relationship: location_of CCO:B0021658 ! NDUS6_HUMAN relationship: location_of CCO:B0054454 ! NDUS4_HUMAN relationship: location_of CCO:B0054644 ! NDUS3_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0063423 ! NDUB9_HUMAN relationship: location_of CCO:B0063424 ! NDUV2_HUMAN relationship: location_of CCO:B0063498 ! NDUS7_HUMAN relationship: location_of CCO:B0063503 ! QCR8_HUMAN relationship: location_of CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0068547 ! NDUA6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068548 ! NDUA7_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068554 ! NDUV1_HUMAN-N6-acetyllysine81 relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0000333 name: mitochondrial respiratory chain complex I namespace: cellular_component def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone." [GOC:mtg_sensu, ISBN:0198547684] synonym: "NADH dehydrogenase complex (ubiquinone) (sensu Eukaryota)" EXACT [] synonym: "respiratory chain complex I (sensu Eukaryota)" EXACT [] xref: GO:0005747 xref: GO:0005748 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001932 ! respiratory chain complex I relationship: location_of CCO:B0006289 ! NDUB8_HUMAN relationship: location_of CCO:B0021658 ! NDUS6_HUMAN relationship: location_of CCO:B0054454 ! NDUS4_HUMAN relationship: location_of CCO:B0054644 ! NDUS3_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0063423 ! NDUB9_HUMAN relationship: location_of CCO:B0063424 ! NDUV2_HUMAN relationship: location_of CCO:B0063498 ! NDUS7_HUMAN relationship: location_of CCO:B0068547 ! NDUA6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068548 ! NDUA7_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068554 ! NDUV1_HUMAN-N6-acetyllysine81 relationship: part_of CCO:C0000332 ! mitochondrial respiratory chain [Term] id: CCO:C0000334 name: mitochondrial respiratory chain complex II namespace: cellular_component def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain." [GOC:mtg_sensu, ISBN:0198547684] synonym: "fumarate reductase complex (sensu Eukaryota)" EXACT [] synonym: "mitochondrial fumarate reductase complex" EXACT [] synonym: "respiratory chain complex II (sensu Eukaryota)" EXACT [] synonym: "succinate dehydrogenase complex (sensu Eukaryota)" EXACT [] synonym: "succinate dehydrogenase complex (ubiquinone) (sensu Eukaryota)" EXACT [] xref: GO:0005749 xref: GO:0008136 xref: GO:0009362 xref: GO:0019738 xref: GO:0030390 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001918 ! succinate dehydrogenase complex (ubiquinone) is_a: CCO:C0001943 ! fumarate reductase complex relationship: part_of CCO:C0000332 ! mitochondrial respiratory chain [Term] id: CCO:C0000335 name: mitochondrial respiratory chain complex III namespace: cellular_component def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1." [GOC:mtg_sensu, ISBN:0198547684] synonym: "respiratory chain complex III (sensu Eukaryota)" EXACT [] synonym: "ubiquinol-cytochrome c oxidoreductase complex (sensu Eukaryota)" EXACT [] synonym: "ubiquinol-cytochrome-c reductase complex (sensu Eukaryota)" EXACT [] xref: GO:0005750 xref: GO:0015008 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001936 ! respiratory chain complex III relationship: part_of CCO:C0000332 ! mitochondrial respiratory chain [Term] id: CCO:C0000336 name: mitochondrial respiratory chain complex IV namespace: cellular_component def: "A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2)." [GOC:mtg_sensu, ISBN:0198547684] synonym: "cytochrome c oxidase complex (sensu Eukaryota)" EXACT [] synonym: "respiratory chain complex IV (sensu Eukaryota)" EXACT [] xref: GO:0005751 xref: GO:0005752 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001938 ! respiratory chain complex IV relationship: part_of CCO:C0000332 ! mitochondrial respiratory chain [Term] id: CCO:C0000337 name: mitochondrial proton-transporting ATP synthase complex namespace: cellular_component def: "A proton-transporting ATP synthase complex found in the mitochondrial membrane." [GOC:mah, GOC:mtg_sensu] synonym: "hydrogen-translocating F-type ATPase complex (sensu Eukaryota)" EXACT [] synonym: "hydrogen-transporting ATP synthase" BROAD [] synonym: "proton-transporting ATP synthase complex (sensu Eukaryota)" EXACT [] synonym: "respiratory chain complex V (sensu Eukaryota)" EXACT [] xref: GO:0005753 xref: GO:0016470 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001920 ! proton-transporting ATP synthase complex relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: location_of CCO:B0065758 ! ATPK_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065764 ! ATPO_HUMAN-N6-acetyllysine176 relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0000338 name: mitochondrial proton-transporting ATP synthase, catalytic core namespace: cellular_component def: "The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase." [GOC:mtg_sensu, PMID:10838056] synonym: "hydrogen-transporting ATP synthase, catalytic core (sensu Eukaryota)" EXACT [] synonym: "proton-transporting ATP synthase, catalytic core (sensu Eukaryota)" EXACT [] xref: GO:0005754 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001928 ! proton-transporting ATP synthase, catalytic core relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: part_of CCO:C0000048 ! mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [Term] id: CCO:C0000339 name: mitochondrial proton-transporting ATP synthase, central stalk namespace: cellular_component def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis." [GOC:mtg_sensu, PMID:10838056] synonym: "hydrogen-transporting ATP synthase, central stalk (sensu Eukaryota)" EXACT [] synonym: "proton-transporting ATP synthase, central stalk (sensu Eukaryota)" EXACT [] xref: GO:0005756 is_a: CCO:C0001874 ! mitochondrial membrane part is_a: CCO:C0001930 ! proton-transporting ATP synthase, central stalk relationship: part_of CCO:C0000048 ! mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [Term] id: CCO:C0000340 name: mitochondrial permeability transition pore complex namespace: cellular_component def: "A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol." [PMID:10393078] synonym: "mitochondrial PT pore complex" EXACT [] xref: GO:0005757 is_a: CCO:C0001848 ! mitochondrial part is_a: CCO:C0001978 ! pore complex relationship: part_of CCO:C0000326 ! mitochondrial envelope [Term] id: CCO:C0000341 name: mitochondrial intermembrane space namespace: cellular_component def: "The region between the inner and outer lipid bilayers of the mitochondrial envelope." [GOC:mah] synonym: "mitochondrial envelope lumen" EXACT [] synonym: "mitochondrial membrane lumen" RELATED [] xref: GO:0005758 xref: GO:0031971 is_a: CCO:C0001363 ! organelle envelope lumen is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0005206 ! NDKM_HUMAN relationship: location_of CCO:B0006089 ! COX17_HUMAN relationship: location_of CCO:B0014938 ! AIFM1_HUMAN relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0065695 ! AR2BP_HUMAN-Phosphoserine157 relationship: part_of CCO:C0000326 ! mitochondrial envelope [Term] id: CCO:C0000342 name: mitochondrial matrix namespace: cellular_component def: "The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty-acid oxidation." [GOC:as, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "mitochondrial stroma" NARROW [] xref: GO:0005759 is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0005496 ! TDRD7_HUMAN relationship: location_of CCO:B0005818 ! DNJA3_HUMAN relationship: location_of CCO:B0006185 ! ODO2_HUMAN relationship: location_of CCO:B0006189 ! ETHE1_HUMAN relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: location_of CCO:B0011197 ! CH60_HUMAN-Phosphoserine70 relationship: location_of CCO:B0016807 ! PDK1_HUMAN relationship: location_of CCO:B0016810 ! PDK3_HUMAN relationship: location_of CCO:B0016811 ! PDK2_HUMAN relationship: location_of CCO:B0023090 ! TMLH_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0035188 ! MDHM_HUMAN-Phosphotyrosine56 relationship: location_of CCO:B0035356 ! PDK4_HUMAN-Phosphohistidine127 relationship: location_of CCO:B0035672 ! SODM_HUMAN-N6-acetyllysine68 relationship: location_of CCO:B0039479 ! K1967_HUMAN-Phosphothreonine454 relationship: location_of CCO:B0054465 ! PROD_HUMAN relationship: location_of CCO:B0055678 ! TFAM_HUMAN relationship: location_of CCO:B0058728 ! TFB2M_HUMAN relationship: location_of CCO:B0058924 ! SIRT3_HUMAN relationship: location_of CCO:B0062956 ! ODPX_HUMAN relationship: location_of CCO:B0063070 ! IDH3A_HUMAN relationship: location_of CCO:B0063220 ! IDH3B_HUMAN relationship: location_of CCO:B0063238 ! ODBB_HUMAN relationship: location_of CCO:B0063251 ! TIM44_HUMAN relationship: location_of CCO:B0063361 ! GLYM_HUMAN relationship: location_of CCO:B0063375 ! ALDH2_HUMAN relationship: location_of CCO:B0063394 ! PIN4_HUMAN relationship: location_of CCO:B0063534 ! SPYA_HUMAN relationship: location_of CCO:B0063791 ! BCKD_HUMAN-Phosphoserine52 relationship: location_of CCO:B0064302 ! CH10_HUMAN-Phosphotyrosine88 relationship: location_of CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0064756 ! DHE3_HUMAN-N6-acetyllysine84 relationship: location_of CCO:B0065801 ! C1QBP_HUMAN-Phosphoserine201 relationship: location_of CCO:B0065953 ! DLDH_HUMAN-N6-acetyllysine127 relationship: location_of CCO:B0065977 ! ECHA_HUMAN-N6-acetyllysine728 relationship: location_of CCO:B0065980 ! ECHB_HUMAN-N6-acetyllysine348 relationship: location_of CCO:B0066301 ! FUMH_HUMAN-Phosphotyrosine491 relationship: location_of CCO:B0066429 ! GCR_HUMAN-Phosphoserine141 relationship: location_of CCO:B0066831 ! HMGCL_HUMAN-N6-acetyllysine48 relationship: location_of CCO:B0068953 ! ODBA_HUMAN-Phosphoserine337 relationship: part_of CCO:C0001372 ! mitochondrial lumen [Term] id: CCO:C0000343 name: gamma DNA polymerase complex namespace: cellular_component def: "A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA." [GOC:jl, PMID:12045093] xref: GO:0005760 is_a: CCO:C0001651 ! DNA polymerase complex is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0017165 ! DPOG1_HUMAN relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000344 name: mitochondrial ribosome namespace: cellular_component def: "A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005761 is_a: CCO:C0000057 ! organellar ribosome is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0006095 ! RT12_HUMAN relationship: location_of CCO:B0055464 ! RT29_HUMAN relationship: location_of CCO:B0055871 ! RM28_HUMAN relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000345 name: mitochondrial large ribosomal subunit namespace: cellular_component def: "The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site)." [GOC:mcc] xref: GO:0005762 is_a: CCO:C0000059 ! organellar large ribosomal subunit is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0001952 ! RM41_HUMAN relationship: location_of CCO:B0043446 ! RM10_HUMAN relationship: location_of CCO:B0055501 ! RM12_HUMAN relationship: part_of CCO:C0000344 ! mitochondrial ribosome [Term] id: CCO:C0000346 name: mitochondrial small ribosomal subunit namespace: cellular_component def: "The smaller of the two subunits of a mitochondrial ribosome." [GOC:mcc] synonym: "mitochondrial ribosomal small subunit complex" EXACT [] synonym: "mitochondrial ribosomal SSU complex" EXACT [] xref: GO:0005763 is_a: CCO:C0000058 ! organellar small ribosomal subunit is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0006288 ! RT26_HUMAN relationship: location_of CCO:B0062930 ! RT18B_HUMAN relationship: location_of CCO:B0070251 ! RT09_HUMAN-Phosphotyrosine262 relationship: part_of CCO:C0000344 ! mitochondrial ribosome [Term] id: CCO:C0000347 name: lysosome namespace: cellular_component def: "Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_plant xref: GO:0005764 is_a: CCO:C0000061 ! lytic vacuole relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006305 ! UBP4_HUMAN relationship: location_of CCO:B0006345 ! CATB_HUMAN relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011886 ! FNBP1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: location_of CCO:B0014569 ! UBP5_HUMAN-Phosphoserine783 relationship: location_of CCO:B0031707 ! CATK_HUMAN relationship: location_of CCO:B0043445 ! HEXA_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0049915 ! RAMP3_HUMAN relationship: location_of CCO:B0054902 ! AGAL_HUMAN relationship: location_of CCO:B0054915 ! HEXB_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0055087 ! ASM_HUMAN relationship: location_of CCO:B0055277 ! UBP6_HUMAN relationship: location_of CCO:B0055282 ! SFTPD_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055613 ! NPC2_HUMAN relationship: location_of CCO:B0055684 ! TIAR_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0057265 ! VPS36_HUMAN relationship: location_of CCO:B0057369 ! SACA3_HUMAN relationship: location_of CCO:B0058153 ! RAB7B_HUMAN relationship: location_of CCO:B0058166 ! ARL8A_HUMAN relationship: location_of CCO:B0058389 ! PKHF1_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058449 ! LITAF_HUMAN relationship: location_of CCO:B0059286 ! LAMP3_HUMAN relationship: location_of CCO:B0062978 ! HPS1_HUMAN relationship: location_of CCO:B0063292 ! SAP_HUMAN relationship: location_of CCO:B0063340 ! 2DRA_HUMAN relationship: location_of CCO:B0063392 ! ASAH1_HUMAN relationship: location_of CCO:B0063398 ! VPS11_HUMAN relationship: location_of CCO:B0063411 ! F176A_HUMAN relationship: location_of CCO:B0063418 ! PPA5_HUMAN relationship: location_of CCO:B0063518 ! IDUA_HUMAN relationship: location_of CCO:B0064358 ! CIP4_HUMAN-Phosphoserine335 relationship: location_of CCO:B0065403 ! ADA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0066894 ! HPS4_HUMAN-Phosphoserine355 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: location_of CCO:B0069234 ! PERM_HUMAN-Cysteine sulfenic acid (-SOH)316 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0069696 ! RAB7A_HUMAN-Cysteine methyl ester207 [Term] id: CCO:C0000348 name: lysosomal membrane namespace: cellular_component def: "The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." [GOC:ai] xref: GO:0005765 is_a: CCO:C0000356 ! vacuolar membrane relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0058166 ! ARL8A_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058449 ! LITAF_HUMAN relationship: location_of CCO:B0059286 ! LAMP3_HUMAN relationship: location_of CCO:B0063398 ! VPS11_HUMAN relationship: location_of CCO:B0063411 ! F176A_HUMAN relationship: location_of CCO:B0065266 ! ABCA2_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: part_of CCO:C0000347 ! lysosome [Term] id: CCO:C0000349 name: primary lysosome namespace: cellular_component def: "A lysosome before it has fused with a vesicle or vacuole." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0005766 is_a: CCO:C0000347 ! lysosome [Term] id: CCO:C0000350 name: secondary lysosome namespace: cellular_component def: "Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0005767 is_a: CCO:C0000347 ! lysosome [Term] id: CCO:C0000351 name: endosome namespace: cellular_component def: "A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_pir subset: goslim_plant xref: GO:0005768 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0001692 ! RHOB_HUMAN relationship: location_of CCO:B0001903 ! STEA3_HUMAN relationship: location_of CCO:B0001980 ! DP13B_HUMAN relationship: location_of CCO:B0002029 ! TP4A1_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0005183 ! PLDN_HUMAN relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005237 ! RB22A_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0005979 ! RFIP4_HUMAN relationship: location_of CCO:B0006187 ! SH3G3_HUMAN relationship: location_of CCO:B0006299 ! VPS29_HUMAN relationship: location_of CCO:B0006310 ! SH3G1_HUMAN relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0012186 ! HGS_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0012636 ! KPCZ_HUMAN-Phosphothreonine560 relationship: location_of CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0023550 ! RAB5C_HUMAN relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0034813 ! FPR1_HUMAN-Phosphothreonine339 relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0038438 ! RB11A_HUMAN relationship: location_of CCO:B0039640 ! RPGF1_HUMAN-Phosphoserine360 relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0054577 ! CYTIP_HUMAN relationship: location_of CCO:B0054584 ! DIAP2_HUMAN relationship: location_of CCO:B0054676 ! RASF9_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0055006 ! ACE_HUMAN relationship: location_of CCO:B0055104 ! ADA2C_HUMAN relationship: location_of CCO:B0055131 ! MAL_HUMAN relationship: location_of CCO:B0055152 ! LSHR_HUMAN relationship: location_of CCO:B0055218 ! BKRB2_HUMAN relationship: location_of CCO:B0055219 ! V2R_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055318 ! V1AR_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055395 ! V1BR_HUMAN relationship: location_of CCO:B0055474 ! CCR5_HUMAN relationship: location_of CCO:B0055616 ! ARF6_HUMAN relationship: location_of CCO:B0055937 ! 5HT4R_HUMAN relationship: location_of CCO:B0057265 ! VPS36_HUMAN relationship: location_of CCO:B0058139 ! RAB24_HUMAN relationship: location_of CCO:B0058156 ! ECOP_HUMAN relationship: location_of CCO:B0058166 ! ARL8A_HUMAN relationship: location_of CCO:B0058264 ! RHOV_HUMAN relationship: location_of CCO:B0058267 ! SNX27_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058883 ! Q9NR26_HUMAN relationship: location_of CCO:B0058930 ! NFIP2_HUMAN relationship: location_of CCO:B0058995 ! SPG21_HUMAN relationship: location_of CCO:B0059131 ! MK1I1_HUMAN relationship: location_of CCO:B0059214 ! RAB21_HUMAN relationship: location_of CCO:B0059328 ! NSG2_HUMAN relationship: location_of CCO:B0062968 ! VPS28_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0063258 ! VPS35_HUMAN relationship: location_of CCO:B0063285 ! RABE1_HUMAN relationship: location_of CCO:B0063303 ! VPP2_HUMAN relationship: location_of CCO:B0063398 ! VPS11_HUMAN relationship: location_of CCO:B0063516 ! M6PBP_HUMAN relationship: location_of CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0064473 ! CRK_HUMAN-Phosphoserine41 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 relationship: location_of CCO:B0066324 ! FYN_HUMAN-Phosphotyrosine213 relationship: location_of CCO:B0066332 ! FYV1_HUMAN-Phosphotyrosine1772 relationship: location_of CCO:B0066377 ! GAPD1_HUMAN-Phosphoserine966 relationship: location_of CCO:B0066584 ! GRB14_HUMAN-Phosphoserine372 relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: location_of CCO:B0068170 ! MIB2_HUMAN-Phosphoserine202 relationship: location_of CCO:B0068706 ! NGF_HUMAN-Phosphoserine84 relationship: location_of CCO:B0068879 ! NTRK1_HUMAN-Phosphotyrosine680 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069696 ! RAB7A_HUMAN-Cysteine methyl ester207 relationship: location_of CCO:B0070716 ! SNX17_HUMAN-Phosphoserine437 relationship: location_of CCO:B0070846 ! SQSTM_HUMAN-Phosphoserine170 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071536 ! TRFE_HUMAN-Omega-N-methylated arginine42 relationship: location_of CCO:B0072026 ! ZFY16_HUMAN-Phosphoserine815 [Term] id: CCO:C0000352 name: early endosome namespace: cellular_component def: "Small irregularly shaped intracellular vesicles to which endocytosed molecules are initially delivered." [GOC:rb] xref: GO:0005769 is_a: CCO:C0000351 ! endosome relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0002029 ! TP4A1_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0005237 ! RB22A_HUMAN relationship: location_of CCO:B0005740 ! CD4_HUMAN relationship: location_of CCO:B0006350 ! VAMP8_HUMAN relationship: location_of CCO:B0012186 ! HGS_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0054577 ! CYTIP_HUMAN relationship: location_of CCO:B0054584 ! DIAP2_HUMAN relationship: location_of CCO:B0054758 ! ZFYV9_HUMAN relationship: location_of CCO:B0054983 ! CD8B_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0056547 ! ARH_HUMAN relationship: location_of CCO:B0058267 ! SNX27_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0059386 ! NOX1_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0063285 ! RABE1_HUMAN relationship: location_of CCO:B0063398 ! VPS11_HUMAN relationship: location_of CCO:B0064792 ! DNER_HUMAN-Phosphotyrosine718 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0070716 ! SNX17_HUMAN-Phosphoserine437 relationship: location_of CCO:B0071447 ! TOM1_HUMAN-Phosphoserine176 relationship: location_of CCO:B0072026 ! ZFY16_HUMAN-Phosphoserine815 [Term] id: CCO:C0000353 name: late endosome namespace: cellular_component def: "A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center." [PMID:11964142, PMID:2557062] synonym: "prevacuolar compartment" EXACT [] synonym: "PVC" BROAD [] xref: GO:0005770 is_a: CCO:C0000351 ! endosome relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0057265 ! VPS36_HUMAN relationship: location_of CCO:B0057954 ! RN128_HUMAN relationship: location_of CCO:B0058139 ! RAB24_HUMAN relationship: location_of CCO:B0059131 ! MK1I1_HUMAN relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0069696 ! RAB7A_HUMAN-Cysteine methyl ester207 relationship: location_of CCO:B0070846 ! SQSTM_HUMAN-Phosphoserine170 [Term] id: CCO:C0000354 name: multivesicular body namespace: cellular_component def: "A type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm." [PMID:11566881] synonym: "multivesicular endosome" EXACT [PMID:12122203] synonym: "MVB" EXACT [] synonym: "MVE" EXACT [PMID:12122203] xref: GO:0005771 is_a: CCO:C0000353 ! late endosome relationship: location_of CCO:B0005283 ! TS101_HUMAN relationship: location_of CCO:B0039671 ! TCTP_HUMAN-Phosphoserine46 relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 [Term] id: CCO:C0000355 name: vacuole namespace: cellular_component def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "vacuolar carboxypeptidase Y" RELATED [] xref: GO:0005773 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0028140 ! VATL_HUMAN relationship: location_of CCO:B0063396 ! VAS1_HUMAN [Term] id: CCO:C0000356 name: vacuolar membrane namespace: cellular_component def: "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." [GOC:ai] subset: gosubset_prok xref: GO:0005774 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001856 ! vacuolar part relationship: location_of CCO:B0028140 ! VATL_HUMAN relationship: location_of CCO:B0063396 ! VAS1_HUMAN [Term] id: CCO:C0000357 name: vacuolar lumen namespace: cellular_component def: "The volume enclosed within the vacuolar membrane." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005775 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001856 ! vacuolar part [Term] id: CCO:C0000358 name: autophagic vacuole namespace: cellular_component def: "A double-membrane bound vesicle in which endogenous cellular material is sequestered; known as autophagosome in yeast." [ISBN:0198547684, PMID:11099404] synonym: "autophagosome" EXACT [] xref: GO:0005776 is_a: CCO:C0000355 ! vacuole relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: location_of CCO:B0051353 ! GBRL1_HUMAN relationship: location_of CCO:B0071730 ! ULK1_HUMAN-Phosphothreonine625 [Term] id: CCO:C0000359 name: peroxisome namespace: cellular_component def: "A small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2)." [ISBN:0815316194] subset: goslim_candida subset: goslim_generic subset: goslim_plant subset: goslim_yeast synonym: "peroxisome vesicle" BROAD [] xref: GO:0005777 xref: GO:0019818 is_a: CCO:C0001652 ! microbody relationship: location_of CCO:B0005312 ! PEX26_HUMAN relationship: location_of CCO:B0006021 ! IDI2_HUMAN relationship: location_of CCO:B0006268 ! ABCD4_HUMAN relationship: location_of CCO:B0013493 ! PEX19_HUMAN-Phosphoserine184 relationship: location_of CCO:B0014534 ! TRI37_HUMAN-Phosphoserine771 relationship: location_of CCO:B0019335 ! CATA_HUMAN relationship: location_of CCO:B0026912 ! PEX6_HUMAN relationship: location_of CCO:B0030742 ! IDE_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0040018 ! GNPAT_HUMAN relationship: location_of CCO:B0050696 ! IDHC_HUMAN relationship: location_of CCO:B0054613 ! PX11A_HUMAN relationship: location_of CCO:B0054797 ! DCMC_HUMAN relationship: location_of CCO:B0054820 ! PX11B_HUMAN relationship: location_of CCO:B0058142 ! MUL1_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0062953 ! KIME_HUMAN relationship: location_of CCO:B0063388 ! PEX2_HUMAN relationship: location_of CCO:B0063534 ! SPYA_HUMAN relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0065947 ! DHB4_HUMAN-Phosphoserine309 relationship: location_of CCO:B0065975 ! ECH1_HUMAN-Phosphoserine30 relationship: location_of CCO:B0068745 ! NLTP_HUMAN-N6-acetyllysine282 relationship: location_of CCO:B0069206 ! PECR_HUMAN-Phosphotyrosine179 relationship: location_of CCO:B0069237 ! PEX14_HUMAN-Phosphoserine335 relationship: location_of CCO:B0071888 ! XDH_HUMAN-Phosphothreonine222 [Term] id: CCO:C0000360 name: peroxisomal membrane namespace: cellular_component def: "The lipid bilayer surrounding a peroxisome." [GOC:mah] synonym: "peroxisome membrane" EXACT [] xref: GO:0005778 is_a: CCO:C0001341 ! microbody membrane is_a: CCO:C0001858 ! peroxisomal part relationship: location_of CCO:B0005312 ! PEX26_HUMAN relationship: location_of CCO:B0006268 ! ABCD4_HUMAN relationship: location_of CCO:B0013493 ! PEX19_HUMAN-Phosphoserine184 relationship: location_of CCO:B0019335 ! CATA_HUMAN relationship: location_of CCO:B0026912 ! PEX6_HUMAN relationship: location_of CCO:B0040018 ! GNPAT_HUMAN relationship: location_of CCO:B0054613 ! PX11A_HUMAN relationship: location_of CCO:B0054820 ! PX11B_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0062824 ! AP2M1_HUMAN relationship: location_of CCO:B0063388 ! PEX2_HUMAN relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069237 ! PEX14_HUMAN-Phosphoserine335 [Term] id: CCO:C0000361 name: integral to peroxisomal membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a peroxisomal membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0005779 is_a: CCO:C0001155 ! intrinsic to peroxisomal membrane is_a: CCO:C0001188 ! integral to organelle membrane relationship: location_of CCO:B0005312 ! PEX26_HUMAN relationship: location_of CCO:B0054613 ! PX11A_HUMAN relationship: location_of CCO:B0054820 ! PX11B_HUMAN relationship: location_of CCO:B0063388 ! PEX2_HUMAN [Term] id: CCO:C0000362 name: extrinsic to intraperoxisomal membrane namespace: cellular_component def: "Loosely bound to the intraperoxisomal surface of the peroxisomal membrane, but not integrated into the hydrophobic region." [GOC:mah] synonym: "intra-peroxisomal peripheral membrane" RELATED [] xref: GO:0005780 is_a: CCO:C0001199 ! extrinsic to organelle membrane is_a: CCO:C0001858 ! peroxisomal part relationship: part_of CCO:C0000360 ! peroxisomal membrane [Term] id: CCO:C0000363 name: peroxisomal matrix namespace: cellular_component def: "The material contained within the membrane of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase." [GOC:mah, ISBN:0815316194] xref: GO:0005782 is_a: CCO:C0001858 ! peroxisomal part relationship: location_of CCO:B0065947 ! DHB4_HUMAN-Phosphoserine309 [Term] id: CCO:C0000364 name: endoplasmic reticulum namespace: cellular_component def: "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "ER" EXACT [] xref: GO:0005783 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0001428 ! ERN1_HUMAN relationship: location_of CCO:B0001541 ! PTN_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0001600 ! VHL_HUMAN relationship: location_of CCO:B0001806 ! DHC24_HUMAN relationship: location_of CCO:B0001818 ! EXT1_HUMAN relationship: location_of CCO:B0001909 ! RINT1_HUMAN relationship: location_of CCO:B0001928 ! ERN2_HUMAN relationship: location_of CCO:B0002028 ! EXT2_HUMAN relationship: location_of CCO:B0002029 ! TP4A1_HUMAN relationship: location_of CCO:B0002078 ! PMYT1_HUMAN relationship: location_of CCO:B0002135 ! PIGU_HUMAN relationship: location_of CCO:B0002157 ! CP26B_HUMAN relationship: location_of CCO:B0005248 ! RCN3_HUMAN relationship: location_of CCO:B0005447 ! NRP1_HUMAN relationship: location_of CCO:B0005483 ! STAU1_HUMAN relationship: location_of CCO:B0005498 ! CREB3_HUMAN relationship: location_of CCO:B0005519 ! SET_HUMAN relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: location_of CCO:B0005619 ! UBQL4_HUMAN relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0005845 ! LRC59_HUMAN relationship: location_of CCO:B0005993 ! TXD11_HUMAN relationship: location_of CCO:B0006136 ! DJB11_HUMAN relationship: location_of CCO:B0006137 ! DNJB9_HUMAN relationship: location_of CCO:B0006148 ! HMOX2_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0006222 ! RAB1A_HUMAN relationship: location_of CCO:B0006273 ! GPAA1_HUMAN relationship: location_of CCO:B0006287 ! ERG28_HUMAN relationship: location_of CCO:B0006289 ! NDUB8_HUMAN relationship: location_of CCO:B0006313 ! SRPRB_HUMAN relationship: location_of CCO:B0006334 ! AMRP_HUMAN relationship: location_of CCO:B0006349 ! SCFD1_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010509 ! AN32A_HUMAN-Phosphoserine158 relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0011943 ! GLU2B_HUMAN-Phosphoserine383 relationship: location_of CCO:B0012274 ! HSP71_HUMAN-Phosphotyrosine611 relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014200 ! SPTC2_HUMAN-Phosphotyrosine387 relationship: location_of CCO:B0014218 ! SSRA_HUMAN-Phosphoserine268 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0018951 ! ATF6A_HUMAN relationship: location_of CCO:B0020068 ! PDIA2_HUMAN relationship: location_of CCO:B0020218 ! CSEN_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0026851 ! HERP1_HUMAN relationship: location_of CCO:B0027148 ! S61A2_HUMAN relationship: location_of CCO:B0027154 ! S61A1_HUMAN relationship: location_of CCO:B0027270 ! FDFT_HUMAN relationship: location_of CCO:B0027593 ! CDIPT_HUMAN relationship: location_of CCO:B0028758 ! SPTC1_HUMAN relationship: location_of CCO:B0030249 ! GNAZ_HUMAN relationship: location_of CCO:B0031878 ! VWF_HUMAN relationship: location_of CCO:B0033136 ! Q8WUM6_HUMAN relationship: location_of CCO:B0033365 ! LASS4_HUMAN relationship: location_of CCO:B0033369 ! LASS6_HUMAN relationship: location_of CCO:B0035088 ! LASS2_HUMAN-Phosphoserine341 relationship: location_of CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0035599 ! RRAS2_HUMAN-Cysteine methyl ester201 relationship: location_of CCO:B0035772 ! TERA_HUMAN-Phosphotyrosine805 relationship: location_of CCO:B0036022 ! PR15A_HUMAN-Phosphotyrosine262 relationship: location_of CCO:B0038202 ! COPA_HUMAN relationship: location_of CCO:B0038991 ! CSTN1_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039642 ! RRBP1_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0039862 ! KLK6_HUMAN relationship: location_of CCO:B0040688 ! RPN1_HUMAN relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0042031 ! PDIA3_HUMAN relationship: location_of CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 relationship: location_of CCO:B0043374 ! RTN4_HUMAN-Phosphoserine863 relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0043817 ! NGX6_HUMAN relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0051353 ! GBRL1_HUMAN relationship: location_of CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 relationship: location_of CCO:B0052719 ! S10A7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: location_of CCO:B0054320 ! DNM1L_HUMAN relationship: location_of CCO:B0054354 ! TPPC2_HUMAN relationship: location_of CCO:B0054386 ! MGST3_HUMAN relationship: location_of CCO:B0054432 ! GPR37_HUMAN relationship: location_of CCO:B0054440 ! INSI1_HUMAN relationship: location_of CCO:B0054556 ! FADS1_HUMAN relationship: location_of CCO:B0054618 ! PDCD6_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054759 ! CNIH_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054925 ! MCR_HUMAN relationship: location_of CCO:B0055025 ! ENPL_HUMAN relationship: location_of CCO:B0055131 ! MAL_HUMAN relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0055194 ! APEX1_HUMAN relationship: location_of CCO:B0055219 ! V2R_HUMAN relationship: location_of CCO:B0055231 ! NTR1_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055378 ! BKRB1_HUMAN relationship: location_of CCO:B0055415 ! CAMLG_HUMAN relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055526 ! BI1_HUMAN relationship: location_of CCO:B0055602 ! RAB2A_HUMAN relationship: location_of CCO:B0055620 ! CNBP_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055740 ! PLP2_HUMAN relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055962 ! KEAP1_HUMAN relationship: location_of CCO:B0056240 ! P3H1_HUMAN relationship: location_of CCO:B0056908 ! CNIH2_HUMAN relationship: location_of CCO:B0056927 ! APOA5_HUMAN relationship: location_of CCO:B0056951 ! MOXD1_HUMAN relationship: location_of CCO:B0057093 ! CR3L2_HUMAN relationship: location_of CCO:B0057421 ! SHSA5_HUMAN relationship: location_of CCO:B0057431 ! CRPAK_HUMAN relationship: location_of CCO:B0057443 ! ARM10_HUMAN relationship: location_of CCO:B0057457 ! PHTF2_HUMAN relationship: location_of CCO:B0057559 ! TXND5_HUMAN relationship: location_of CCO:B0057954 ! RN128_HUMAN relationship: location_of CCO:B0057958 ! CR3L4_HUMAN relationship: location_of CCO:B0057977 ! RAB2B_HUMAN relationship: location_of CCO:B0057997 ! CANT1_HUMAN relationship: location_of CCO:B0058062 ! NICA_HUMAN relationship: location_of CCO:B0058104 ! KIFA3_HUMAN relationship: location_of CCO:B0058110 ! CDS1_HUMAN relationship: location_of CCO:B0058139 ! RAB24_HUMAN relationship: location_of CCO:B0058161 ! CR3L1_HUMAN relationship: location_of CCO:B0058164 ! APH1A_HUMAN relationship: location_of CCO:B0058311 ! AIFM3_HUMAN relationship: location_of CCO:B0058351 ! DERL3_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058422 ! GPER_HUMAN relationship: location_of CCO:B0058450 ! MGST2_HUMAN relationship: location_of CCO:B0058463 ! ATF6B_HUMAN relationship: location_of CCO:B0058469 ! P2Y13_HUMAN relationship: location_of CCO:B0058480 ! SELS_HUMAN relationship: location_of CCO:B0058489 ! PLCD4_HUMAN relationship: location_of CCO:B0058502 ! TXND4_HUMAN relationship: location_of CCO:B0058631 ! DERL2_HUMAN relationship: location_of CCO:B0058674 ! PORCN_HUMAN relationship: location_of CCO:B0058705 ! TXND1_HUMAN relationship: location_of CCO:B0058712 ! OFUT1_HUMAN relationship: location_of CCO:B0058815 ! HHATL_HUMAN relationship: location_of CCO:B0058819 ! PREB_HUMAN relationship: location_of CCO:B0058849 ! CD320_HUMAN relationship: location_of CCO:B0058854 ! NOX4_HUMAN relationship: location_of CCO:B0058862 ! ISK5_HUMAN relationship: location_of CCO:B0058866 ! A1CF_HUMAN relationship: location_of CCO:B0058885 ! SAR1A_HUMAN relationship: location_of CCO:B0058975 ! T2R16_HUMAN relationship: location_of CCO:B0058989 ! PEN2_HUMAN relationship: location_of CCO:B0059015 ! BFAR_HUMAN relationship: location_of CCO:B0059024 ! CNIH4_HUMAN relationship: location_of CCO:B0059077 ! PEMT_HUMAN relationship: location_of CCO:B0059078 ! DHCR7_HUMAN relationship: location_of CCO:B0059086 ! SE1L1_HUMAN relationship: location_of CCO:B0059091 ! CLN8_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059206 ! AMFR2_HUMAN relationship: location_of CCO:B0059335 ! GOT1B_HUMAN relationship: location_of CCO:B0059343 ! GRIP1_HUMAN relationship: location_of CCO:B0059403 ! SAR1B_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0062787 ! STX8_HUMAN relationship: location_of CCO:B0062790 ! PLOD3_HUMAN relationship: location_of CCO:B0062847 ! DHRS1_HUMAN relationship: location_of CCO:B0062906 ! SERP2_HUMAN relationship: location_of CCO:B0062910 ! FATE1_HUMAN relationship: location_of CCO:B0062917 ! SNAA_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0063007 ! ANTR2_HUMAN relationship: location_of CCO:B0063014 ! AHSA1_HUMAN relationship: location_of CCO:B0063067 ! CALX_HUMAN relationship: location_of CCO:B0063081 ! SSRD_HUMAN relationship: location_of CCO:B0063088 ! RCN2_HUMAN relationship: location_of CCO:B0063093 ! RL10_HUMAN relationship: location_of CCO:B0063104 ! PLOD1_HUMAN relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0063209 ! CALU_HUMAN relationship: location_of CCO:B0063210 ! RCN1_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0063334 ! ERG25_HUMAN relationship: location_of CCO:B0063363 ! SERPH_HUMAN relationship: location_of CCO:B0063390 ! TMPS3_HUMAN relationship: location_of CCO:B0063411 ! F176A_HUMAN relationship: location_of CCO:B0063449 ! STT3A_HUMAN relationship: location_of CCO:B0063481 ! PIGC_HUMAN relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: location_of CCO:B0064367 ! CKAP4_HUMAN-Phosphoserine312 relationship: location_of CCO:B0064391 ! CLN6_HUMAN-Phosphoserine31 relationship: location_of CCO:B0064461 ! CR3L3_HUMAN-Phosphoserine256 relationship: location_of CCO:B0064741 ! DERL1_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0065416 ! ADIPO_HUMAN-5-hydroxylysine65 relationship: location_of CCO:B0065804 ! C43BP_HUMAN-Phosphoserine377 relationship: location_of CCO:B0066552 ! GPSM1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0067115 ! INGR2_HUMAN-Phosphoserine198 relationship: location_of CCO:B0067166 ! ITPR1_HUMAN-Phosphoserine1598 relationship: location_of CCO:B0067170 ! ITPR2_HUMAN-Phosphotyrosine2607 relationship: location_of CCO:B0067173 ! ITPR3_HUMAN-Phosphoserine1832 relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: location_of CCO:B0067513 ! KTN1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0068463 ! NCK1_HUMAN-Phosphoserine96 relationship: location_of CCO:B0068465 ! NCK2_HUMAN-Phosphothreonine92 relationship: location_of CCO:B0068521 ! NCPR_HUMAN-Phosphotyrosine575 relationship: location_of CCO:B0068994 ! OREX_HUMAN-Methionine amide97 relationship: location_of CCO:B0069187 ! PDIA6_HUMAN-Phosphoserine428 relationship: location_of CCO:B0069292 ! PI42B_HUMAN-Phosphotyrosine98 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069309 ! PIMT_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0069601 ! PTN1_HUMAN-Phosphoserine386 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069921 ! RGRF2_HUMAN-Phosphoserine737 relationship: location_of CCO:B0070101 ! RN139_HUMAN-Phosphoserine625 relationship: location_of CCO:B0070259 ! RTN1_HUMAN-Phosphoserine487 relationship: location_of CCO:B0070260 ! RTN2_HUMAN-Phosphoserine44 relationship: location_of CCO:B0070338 ! SC16A_HUMAN-Phosphoserine1905 relationship: location_of CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070676 ! SNAG_HUMAN-Phosphoserine284 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 relationship: location_of CCO:B0071842 ! WFS1_HUMAN-Phosphoserine32 [Term] id: CCO:C0000365 name: translocon complex namespace: cellular_component def: "A translocation complex that constitutes the specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. Composed of a heterotetramer of alpha, beta, gamma and delta subunits (translocon-associated proteins or TRAPs). In yeast it is a heterotrimeric complex consisting of Sec61p, Sbh1p, and Sss1p. The Sec61 complex functions in cotranslational and posttranslational translocation events." [GOC:rb, ISBN:0198599471] subset: goslim_pir synonym: "sec61 complex" NARROW [] xref: GO:0005784 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: location_of CCO:B0063081 ! SSRD_HUMAN relationship: part_of CCO:C0001057 ! rough endoplasmic reticulum membrane [Term] id: CCO:C0000366 name: signal recognition particle receptor complex namespace: cellular_component def: "A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "docking protein complex" RELATED [] synonym: "SR complex" EXACT [] xref: GO:0005785 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: location_of CCO:B0051562 ! SRP09_HUMAN relationship: part_of CCO:C0001057 ! rough endoplasmic reticulum membrane [Term] id: CCO:C0000367 name: signal recognition particle, endoplasmic reticulum targeting namespace: cellular_component def: "A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA." [GOC:mtg_sensu, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "signal recognition particle (sensu Eukaryota)" EXACT [] synonym: "signal sequence receptor complex" EXACT [] synonym: "SRP" EXACT [] xref: GO:0005786 xref: GO:0005855 is_a: CCO:C0002002 ! signal recognition particle relationship: location_of CCO:B0051562 ! SRP09_HUMAN relationship: location_of CCO:B0055316 ! SRP14_HUMAN [Term] id: CCO:C0000368 name: signal peptidase complex namespace: cellular_component def: "A multi subunit protease complex located in the endoplasmic reticulum membrane that cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space." [GOC:sgd_curators, PMID:1846444, PMID:7615509] xref: GO:0005787 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0000369 name: endoplasmic reticulum lumen namespace: cellular_component def: "The volume enclosed by the membranes of the endoplasmic reticulum." [ISBN:0198547684] synonym: "cisternal lumen" EXACT [] synonym: "endoplasmic reticulum cisterna" EXACT [] synonym: "ER cisterna" EXACT [] synonym: "ER lumen" EXACT [] xref: GO:0005788 xref: GO:0016022 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0005248 ! RCN3_HUMAN relationship: location_of CCO:B0006136 ! DJB11_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0020068 ! PDIA2_HUMAN relationship: location_of CCO:B0028600 ! APOA1_HUMAN relationship: location_of CCO:B0042031 ! PDIA3_HUMAN relationship: location_of CCO:B0054863 ! APOA2_HUMAN relationship: location_of CCO:B0055025 ! ENPL_HUMAN relationship: location_of CCO:B0057559 ! TXND5_HUMAN relationship: location_of CCO:B0058502 ! TXND4_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0063088 ! RCN2_HUMAN relationship: location_of CCO:B0063209 ! CALU_HUMAN relationship: location_of CCO:B0063210 ! RCN1_HUMAN relationship: location_of CCO:B0063363 ! SERPH_HUMAN relationship: location_of CCO:B0064391 ! CLN6_HUMAN-Phosphoserine31 relationship: location_of CCO:B0069187 ! PDIA6_HUMAN-Phosphoserine428 [Term] id: CCO:C0000370 name: endoplasmic reticulum membrane namespace: cellular_component def: "The lipid bilayer surrounding the endoplasmic reticulum." [GOC:mah] synonym: "ER membrane" EXACT [] xref: GO:0005789 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: location_of CCO:B0001428 ! ERN1_HUMAN relationship: location_of CCO:B0001806 ! DHC24_HUMAN relationship: location_of CCO:B0001818 ! EXT1_HUMAN relationship: location_of CCO:B0001909 ! RINT1_HUMAN relationship: location_of CCO:B0001928 ! ERN2_HUMAN relationship: location_of CCO:B0002028 ! EXT2_HUMAN relationship: location_of CCO:B0002078 ! PMYT1_HUMAN relationship: location_of CCO:B0002135 ! PIGU_HUMAN relationship: location_of CCO:B0002157 ! CP26B_HUMAN relationship: location_of CCO:B0005498 ! CREB3_HUMAN relationship: location_of CCO:B0005619 ! UBQL4_HUMAN relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0005740 ! CD4_HUMAN relationship: location_of CCO:B0005845 ! LRC59_HUMAN relationship: location_of CCO:B0005993 ! TXD11_HUMAN relationship: location_of CCO:B0006019 ! LPP3_HUMAN relationship: location_of CCO:B0006273 ! GPAA1_HUMAN relationship: location_of CCO:B0006287 ! ERG28_HUMAN relationship: location_of CCO:B0006313 ! SRPRB_HUMAN relationship: location_of CCO:B0006349 ! SCFD1_HUMAN relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014200 ! SPTC2_HUMAN-Phosphotyrosine387 relationship: location_of CCO:B0014218 ! SSRA_HUMAN-Phosphoserine268 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0018187 ! Q5JWU1_HUMAN relationship: location_of CCO:B0018951 ! ATF6A_HUMAN relationship: location_of CCO:B0026851 ! HERP1_HUMAN relationship: location_of CCO:B0027148 ! S61A2_HUMAN relationship: location_of CCO:B0027154 ! S61A1_HUMAN relationship: location_of CCO:B0027270 ! FDFT_HUMAN relationship: location_of CCO:B0027593 ! CDIPT_HUMAN relationship: location_of CCO:B0028758 ! SPTC1_HUMAN relationship: location_of CCO:B0033365 ! LASS4_HUMAN relationship: location_of CCO:B0033369 ! LASS6_HUMAN relationship: location_of CCO:B0035088 ! LASS2_HUMAN-Phosphoserine341 relationship: location_of CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0038991 ! CSTN1_HUMAN relationship: location_of CCO:B0039642 ! RRBP1_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0040688 ! RPN1_HUMAN relationship: location_of CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 relationship: location_of CCO:B0043374 ! RTN4_HUMAN-Phosphoserine863 relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 relationship: location_of CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: location_of CCO:B0054386 ! MGST3_HUMAN relationship: location_of CCO:B0054432 ! GPR37_HUMAN relationship: location_of CCO:B0054440 ! INSI1_HUMAN relationship: location_of CCO:B0054556 ! FADS1_HUMAN relationship: location_of CCO:B0054618 ! PDCD6_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054759 ! CNIH_HUMAN relationship: location_of CCO:B0054925 ! MCR_HUMAN relationship: location_of CCO:B0055025 ! ENPL_HUMAN relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055530 ! CASP7_HUMAN relationship: location_of CCO:B0055602 ! RAB2A_HUMAN relationship: location_of CCO:B0055740 ! PLP2_HUMAN relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0056908 ! CNIH2_HUMAN relationship: location_of CCO:B0056951 ! MOXD1_HUMAN relationship: location_of CCO:B0057093 ! CR3L2_HUMAN relationship: location_of CCO:B0057421 ! SHSA5_HUMAN relationship: location_of CCO:B0057443 ! ARM10_HUMAN relationship: location_of CCO:B0057958 ! CR3L4_HUMAN relationship: location_of CCO:B0057977 ! RAB2B_HUMAN relationship: location_of CCO:B0057997 ! CANT1_HUMAN relationship: location_of CCO:B0058110 ! CDS1_HUMAN relationship: location_of CCO:B0058161 ! CR3L1_HUMAN relationship: location_of CCO:B0058164 ! APH1A_HUMAN relationship: location_of CCO:B0058325 ! NECA3_HUMAN relationship: location_of CCO:B0058351 ! DERL3_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058422 ! GPER_HUMAN relationship: location_of CCO:B0058450 ! MGST2_HUMAN relationship: location_of CCO:B0058463 ! ATF6B_HUMAN relationship: location_of CCO:B0058480 ! SELS_HUMAN relationship: location_of CCO:B0058502 ! TXND4_HUMAN relationship: location_of CCO:B0058631 ! DERL2_HUMAN relationship: location_of CCO:B0058674 ! PORCN_HUMAN relationship: location_of CCO:B0058705 ! TXND1_HUMAN relationship: location_of CCO:B0058819 ! PREB_HUMAN relationship: location_of CCO:B0058854 ! NOX4_HUMAN relationship: location_of CCO:B0058862 ! ISK5_HUMAN relationship: location_of CCO:B0058989 ! PEN2_HUMAN relationship: location_of CCO:B0059015 ! BFAR_HUMAN relationship: location_of CCO:B0059077 ! PEMT_HUMAN relationship: location_of CCO:B0059078 ! DHCR7_HUMAN relationship: location_of CCO:B0059086 ! SE1L1_HUMAN relationship: location_of CCO:B0059091 ! CLN8_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059206 ! AMFR2_HUMAN relationship: location_of CCO:B0059403 ! SAR1B_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0062906 ! SERP2_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0063007 ! ANTR2_HUMAN relationship: location_of CCO:B0063067 ! CALX_HUMAN relationship: location_of CCO:B0063081 ! SSRD_HUMAN relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0063334 ! ERG25_HUMAN relationship: location_of CCO:B0063390 ! TMPS3_HUMAN relationship: location_of CCO:B0063411 ! F176A_HUMAN relationship: location_of CCO:B0063449 ! STT3A_HUMAN relationship: location_of CCO:B0063481 ! PIGC_HUMAN relationship: location_of CCO:B0064391 ! CLN6_HUMAN-Phosphoserine31 relationship: location_of CCO:B0064461 ! CR3L3_HUMAN-Phosphoserine256 relationship: location_of CCO:B0064741 ! DERL1_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0066552 ! GPSM1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0067166 ! ITPR1_HUMAN-Phosphoserine1598 relationship: location_of CCO:B0067170 ! ITPR2_HUMAN-Phosphotyrosine2607 relationship: location_of CCO:B0067173 ! ITPR3_HUMAN-Phosphoserine1832 relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: location_of CCO:B0067513 ! KTN1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0068521 ! NCPR_HUMAN-Phosphotyrosine575 relationship: location_of CCO:B0069292 ! PI42B_HUMAN-Phosphotyrosine98 relationship: location_of CCO:B0069601 ! PTN1_HUMAN-Phosphoserine386 relationship: location_of CCO:B0069921 ! RGRF2_HUMAN-Phosphoserine737 relationship: location_of CCO:B0070101 ! RN139_HUMAN-Phosphoserine625 relationship: location_of CCO:B0070259 ! RTN1_HUMAN-Phosphoserine487 relationship: location_of CCO:B0070260 ! RTN2_HUMAN-Phosphoserine44 relationship: location_of CCO:B0070338 ! SC16A_HUMAN-Phosphoserine1905 relationship: location_of CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 relationship: location_of CCO:B0071842 ! WFS1_HUMAN-Phosphoserine32 relationship: part_of CCO:C0001635 ! nuclear envelope-endoplasmic reticulum network [Term] id: CCO:C0000371 name: smooth endoplasmic reticulum namespace: cellular_component def: "The smooth endoplasmic reticulum (ER) has with no ribosomes attached to it. The smooth is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "smooth ER" EXACT [] xref: GO:0005790 is_a: CCO:C0000364 ! endoplasmic reticulum relationship: location_of CCO:B0006196 ! GBRAP_HUMAN [Term] id: CCO:C0000372 name: rough endoplasmic reticulum namespace: cellular_component def: "The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "rough ER" EXACT [] xref: GO:0005791 is_a: CCO:C0000364 ! endoplasmic reticulum relationship: location_of CCO:B0005483 ! STAU1_HUMAN relationship: location_of CCO:B0057558 ! PCSK9_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0068994 ! OREX_HUMAN-Methionine amide97 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 [Term] id: CCO:C0000373 name: microsome namespace: cellular_component def: "Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. synonym: "microsomal membrane" RELATED [] xref: GO:0005792 is_a: CCO:C0001663 ! vesicular fraction relationship: location_of CCO:B0001370 ! FANCG_HUMAN relationship: location_of CCO:B0002157 ! CP26B_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005572 ! GNPTG_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0005845 ! LRC59_HUMAN relationship: location_of CCO:B0006148 ! HMOX2_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0012337 ! IGF1R_HUMAN-Phosphotyrosine1161 relationship: location_of CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: location_of CCO:B0035772 ! TERA_HUMAN-Phosphotyrosine805 relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039862 ! KLK6_HUMAN relationship: location_of CCO:B0048872 ! ALS_HUMAN relationship: location_of CCO:B0052463 ! IRS1_HUMAN-Phosphotyrosine632 relationship: location_of CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 relationship: location_of CCO:B0054386 ! MGST3_HUMAN relationship: location_of CCO:B0054556 ! FADS1_HUMAN relationship: location_of CCO:B0055025 ! ENPL_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0057878 ! B4GN2_HUMAN relationship: location_of CCO:B0057978 ! CHPT1_HUMAN relationship: location_of CCO:B0058059 ! CPT1B_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058450 ! MGST2_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0063160 ! COMT_HUMAN relationship: location_of CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 [Term] id: CCO:C0000374 name: ER-Golgi intermediate compartment namespace: cellular_component def: "A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport." [PMID:16723730] synonym: "endoplasmic reticulum-Golgi intermediate compartment" EXACT [] synonym: "ERGIC" EXACT [] synonym: "pre-Golgi intermediate compartment" EXACT [] xref: GO:0005793 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0031949 ! FINC_HUMAN relationship: location_of CCO:B0034942 ! K0174_HUMAN-Phosphotyrosine43 relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0056863 ! RGMB_HUMAN relationship: location_of CCO:B0058132 ! CS010_HUMAN relationship: location_of CCO:B0058139 ! RAB24_HUMAN relationship: location_of CCO:B0058157 ! RAB37_HUMAN relationship: location_of CCO:B0058502 ! TXND4_HUMAN relationship: location_of CCO:B0059091 ! CLN8_HUMAN relationship: location_of CCO:B0063363 ! SERPH_HUMAN relationship: location_of CCO:B0066508 ! GOGB1_HUMAN-Phosphoserine17 relationship: location_of CCO:B0068346 ! MY18A_HUMAN-Phosphoserine2020 relationship: location_of CCO:B0069187 ! PDIA6_HUMAN-Phosphoserine428 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 [Term] id: CCO:C0000375 name: Golgi apparatus namespace: cellular_component def: "A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon. subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "Golgi" BROAD [] synonym: "Golgi complex" EXACT [] synonym: "Golgi ribbon" NARROW [] xref: GO:0005794 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0001466 ! RASN_HUMAN relationship: location_of CCO:B0001557 ! PAR1_HUMAN relationship: location_of CCO:B0001806 ! DHC24_HUMAN relationship: location_of CCO:B0001818 ! EXT1_HUMAN relationship: location_of CCO:B0002028 ! EXT2_HUMAN relationship: location_of CCO:B0002078 ! PMYT1_HUMAN relationship: location_of CCO:B0002175 ! NSMA2_HUMAN relationship: location_of CCO:B0002181 ! WWOX_HUMAN relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005220 ! STX11_HUMAN relationship: location_of CCO:B0005247 ! CHST1_HUMAN relationship: location_of CCO:B0005572 ! GNPTG_HUMAN relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: location_of CCO:B0005706 ! M4K2_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0005950 ! BECN1_HUMAN relationship: location_of CCO:B0006019 ! LPP3_HUMAN relationship: location_of CCO:B0006164 ! STX5_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006222 ! RAB1A_HUMAN relationship: location_of CCO:B0006227 ! PRKN2_HUMAN relationship: location_of CCO:B0006258 ! ARSE_HUMAN relationship: location_of CCO:B0006320 ! CHSS2_HUMAN relationship: location_of CCO:B0006331 ! GOLM1_HUMAN relationship: location_of CCO:B0006349 ! SCFD1_HUMAN relationship: location_of CCO:B0010486 ! AKAP9_HUMAN-Phosphoserine3869 relationship: location_of CCO:B0010590 ! ARFG1_HUMAN-Phosphothreonine189 relationship: location_of CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0011413 ! CUL3_HUMAN-Phosphoserine737 relationship: location_of CCO:B0011920 ! GAK_HUMAN-Phosphoserine829 relationship: location_of CCO:B0011921 ! GBF1_HUMAN-Phosphoserine1773 relationship: location_of CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0011955 ! GOGA2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0011961 ! GORS2_HUMAN-Phosphothreonine225 relationship: location_of CCO:B0011973 ! GRB2_HUMAN-Phosphotyrosine160 relationship: location_of CCO:B0012175 ! HD_HUMAN-Phosphoserine421 relationship: location_of CCO:B0012763 ! MARE1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012974 ! MP2K1_HUMAN-Phosphoserine218 relationship: location_of CCO:B0013046 ! MTUS1_HUMAN-Phosphoserine1264 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: location_of CCO:B0015284 ! ARF3_HUMAN relationship: location_of CCO:B0015288 ! ARF1_HUMAN relationship: location_of CCO:B0020052 ! CHIC2_HUMAN relationship: location_of CCO:B0020218 ! CSEN_HUMAN relationship: location_of CCO:B0022753 ! MST4_HUMAN relationship: location_of CCO:B0026268 ! CACO2_HUMAN relationship: location_of CCO:B0026448 ! AT2C1_HUMAN relationship: location_of CCO:B0027593 ! CDIPT_HUMAN relationship: location_of CCO:B0028281 ! ARL1_HUMAN relationship: location_of CCO:B0031198 ! MOBL3_HUMAN relationship: location_of CCO:B0031540 ! APC2_HUMAN relationship: location_of CCO:B0032549 ! RAB10_HUMAN relationship: location_of CCO:B0035392 ! PKN3_HUMAN-Phosphoserine544 relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0035557 ! RGS19_HUMAN-Phosphoserine24 relationship: location_of CCO:B0035594 ! RND3_HUMAN-Cysteine methyl ester241 relationship: location_of CCO:B0035707 ! STK25_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0038854 ! FZD5_HUMAN relationship: location_of CCO:B0038991 ! CSTN1_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0041173 ! RASH_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0043552 ! PI51A_HUMAN relationship: location_of CCO:B0049161 ! PAR2_HUMAN relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0051353 ! GBRL1_HUMAN relationship: location_of CCO:B0052399 ! GBRL2_HUMAN-Phosphoserine10 relationship: location_of CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: location_of CCO:B0054322 ! LST1_HUMAN relationship: location_of CCO:B0054354 ! TPPC2_HUMAN relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0054601 ! MTG16_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0054759 ! CNIH_HUMAN relationship: location_of CCO:B0054792 ! RAB36_HUMAN relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054902 ! AGAL_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055099 ! ARF4_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055219 ! V2R_HUMAN relationship: location_of CCO:B0055231 ! NTR1_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055356 ! NSG1_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055384 ! RPGP1_HUMAN relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055504 ! NDST2_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0055602 ! RAB2A_HUMAN relationship: location_of CCO:B0055616 ! ARF6_HUMAN relationship: location_of CCO:B0055660 ! COG7_HUMAN relationship: location_of CCO:B0055662 ! ARF5_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055836 ! BST2_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055942 ! ARFRP_HUMAN relationship: location_of CCO:B0056218 ! SGSM1_HUMAN relationship: location_of CCO:B0056639 ! RAIN_HUMAN relationship: location_of CCO:B0056643 ! GKAP1_HUMAN relationship: location_of CCO:B0056953 ! ENPP7_HUMAN relationship: location_of CCO:B0056974 ! DNMBP_HUMAN relationship: location_of CCO:B0057029 ! FGD5_HUMAN relationship: location_of CCO:B0057113 ! RHOU_HUMAN relationship: location_of CCO:B0057198 ! FGD2_HUMAN relationship: location_of CCO:B0057293 ! TCAM2_HUMAN relationship: location_of CCO:B0057294 ! CEP57_HUMAN relationship: location_of CCO:B0057324 ! ZDH17_HUMAN relationship: location_of CCO:B0057878 ! B4GN2_HUMAN relationship: location_of CCO:B0057945 ! CGAT1_HUMAN relationship: location_of CCO:B0057954 ! RN128_HUMAN relationship: location_of CCO:B0057977 ! RAB2B_HUMAN relationship: location_of CCO:B0057978 ! CHPT1_HUMAN relationship: location_of CCO:B0057996 ! SCTM1_HUMAN relationship: location_of CCO:B0057997 ! CANT1_HUMAN relationship: location_of CCO:B0058062 ! NICA_HUMAN relationship: location_of CCO:B0058066 ! AP3S1_HUMAN relationship: location_of CCO:B0058081 ! RSCA1_HUMAN relationship: location_of CCO:B0058139 ! RAB24_HUMAN relationship: location_of CCO:B0058164 ! APH1A_HUMAN relationship: location_of CCO:B0058282 ! FGD4_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058422 ! GPER_HUMAN relationship: location_of CCO:B0058449 ! LITAF_HUMAN relationship: location_of CCO:B0058512 ! NFIP1_HUMAN relationship: location_of CCO:B0058755 ! MA6D1_HUMAN relationship: location_of CCO:B0058841 ! RAB9B_HUMAN relationship: location_of CCO:B0058885 ! SAR1A_HUMAN relationship: location_of CCO:B0058930 ! NFIP2_HUMAN relationship: location_of CCO:B0058949 ! RAB20_HUMAN relationship: location_of CCO:B0058989 ! PEN2_HUMAN relationship: location_of CCO:B0058995 ! SPG21_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059087 ! B4GT7_HUMAN relationship: location_of CCO:B0059110 ! VTI1B_HUMAN relationship: location_of CCO:B0059139 ! PCSK1_HUMAN relationship: location_of CCO:B0059214 ! RAB21_HUMAN relationship: location_of CCO:B0059328 ! NSG2_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0059335 ! GOT1B_HUMAN relationship: location_of CCO:B0059339 ! CBY1_HUMAN relationship: location_of CCO:B0059403 ! SAR1B_HUMAN relationship: location_of CCO:B0062770 ! ZDHC3_HUMAN relationship: location_of CCO:B0062773 ! ITM2C_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062861 ! NCS1_HUMAN relationship: location_of CCO:B0062917 ! SNAA_HUMAN relationship: location_of CCO:B0062937 ! CCD91_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: location_of CCO:B0063024 ! COG5_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063139 ! GSLG1_HUMAN relationship: location_of CCO:B0063204 ! AP1B1_HUMAN relationship: location_of CCO:B0063209 ! CALU_HUMAN relationship: location_of CCO:B0063288 ! B3GN9_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063322 ! ENTP6_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0063333 ! Q5SQU0_HUMAN relationship: location_of CCO:B0063336 ! SIA7F_HUMAN relationship: location_of CCO:B0063384 ! MA2A2_HUMAN relationship: location_of CCO:B0063432 ! RER1_HUMAN relationship: location_of CCO:B0063516 ! M6PBP_HUMAN relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: location_of CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 relationship: location_of CCO:B0064259 ! CEND2_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0064358 ! CIP4_HUMAN-Phosphoserine335 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0064448 ! COG3_HUMAN-Phosphoserine533 relationship: location_of CCO:B0064689 ! DDEF2_HUMAN-Phosphoserine701 relationship: location_of CCO:B0065658 ! AP1M1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: location_of CCO:B0065667 ! AP3B1_HUMAN-Phosphoserine609 relationship: location_of CCO:B0065672 ! AP3D1_HUMAN-Phosphoserine759 relationship: location_of CCO:B0065704 ! ARFG2_HUMAN-Phosphoserine498 relationship: location_of CCO:B0065705 ! ARFG3_HUMAN-Phosphoserine143 relationship: location_of CCO:B0065804 ! C43BP_HUMAN-Phosphoserine377 relationship: location_of CCO:B0065888 ! COG4_HUMAN-Phosphotyrosine714 relationship: location_of CCO:B0066020 ! EPN4_HUMAN-Phosphoserine232 relationship: location_of CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: location_of CCO:B0066179 ! FGD3_HUMAN-Phosphoserine128 relationship: location_of CCO:B0066183 ! FGD6_HUMAN-Phosphoserine721 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0066362 ! GALA_HUMAN-Phosphoserine117 relationship: location_of CCO:B0066486 ! GNAI3_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0066505 ! GO45_HUMAN-Phosphoserine353 relationship: location_of CCO:B0066508 ! GOGB1_HUMAN-Phosphoserine17 relationship: location_of CCO:B0066552 ! GPSM1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0066584 ! GRB14_HUMAN-Phosphoserine372 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0068866 ! NSF1C_HUMAN-Phosphoserine114 relationship: location_of CCO:B0068980 ! OPTN_HUMAN-Phosphoserine177 relationship: location_of CCO:B0069075 ! PAK4_HUMAN-Phosphoserine474 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069663 ! RAB12_HUMAN-Phosphoserine25 relationship: location_of CCO:B0069673 ! RAB1B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069678 ! RAB34_HUMAN-Phosphoserine241 relationship: location_of CCO:B0069690 ! RAB6A_HUMAN-N-acetylserine2 relationship: location_of CCO:B0069693 ! RAB6B_HUMAN-Cysteine methyl ester208 relationship: location_of CCO:B0069757 ! RB27B_HUMAN-Cysteine methyl ester218 relationship: location_of CCO:B0069759 ! RB33B_HUMAN-Cysteine methyl ester229 relationship: location_of CCO:B0069763 ! RB6I2_HUMAN-Phosphoserine17 relationship: location_of CCO:B0069839 ! RCAS1_HUMAN-Phosphothreonine41 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0070132 ! ROCK1_HUMAN-Phosphothreonine1180 relationship: location_of CCO:B0070283 ! S35B2_HUMAN-Phosphoserine427 relationship: location_of CCO:B0070338 ! SC16A_HUMAN-Phosphoserine1905 relationship: location_of CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: location_of CCO:B0070377 ! SERC3_HUMAN-Phosphoserine371 relationship: location_of CCO:B0070676 ! SNAG_HUMAN-Phosphoserine284 relationship: location_of CCO:B0070716 ! SNX17_HUMAN-Phosphoserine437 relationship: location_of CCO:B0070985 ! STX12_HUMAN-Phosphoserine142 relationship: location_of CCO:B0071048 ! SYN1_HUMAN-Phosphotyrosine312 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 relationship: location_of CCO:B0071432 ! TMM22_HUMAN-Phosphoserine409 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: location_of CCO:B0071733 ! UN13B_HUMAN-Phosphothreonine605 relationship: location_of CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 [Term] id: CCO:C0000376 name: Golgi stack namespace: cellular_component def: "The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack." [GOC:mah, ISBN:0815316194] synonym: "dictyosome" NARROW [] synonym: "Golgi cisternae" EXACT [] xref: GO:0005795 xref: GO:0016940 is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0055698 ! OCRL_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0056108 ! RAB30_HUMAN relationship: location_of CCO:B0066508 ! GOGB1_HUMAN-Phosphoserine17 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 [Term] id: CCO:C0000377 name: Golgi lumen namespace: cellular_component def: "The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks." [GOC:mah] xref: GO:0005796 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0001471 ! TGFB1_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0066505 ! GO45_HUMAN-Phosphoserine353 relationship: location_of CCO:B0068706 ! NGF_HUMAN-Phosphoserine84 [Term] id: CCO:C0000378 name: Golgi medial cisterna namespace: cellular_component def: "The middle Golgi cisterna (or cisternae)." [ISBN:0815316194] xref: GO:0005797 is_a: CCO:C0001377 ! Golgi cisterna relationship: location_of CCO:B0011961 ! GORS2_HUMAN-Phosphothreonine225 [Term] id: CCO:C0000379 name: Golgi-associated vesicle namespace: cellular_component def: "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." [GOC:mah] comment: Note that this definition includes vesicles that are transiently associated with the Golgi. synonym: "Golgi vesicle" RELATED [] xref: GO:0005798 is_a: CCO:C0001850 ! Golgi apparatus part is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: location_of CCO:B0020052 ! CHIC2_HUMAN relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0055350 ! PI4KA_HUMAN relationship: location_of CCO:B0055698 ! OCRL_HUMAN relationship: location_of CCO:B0058755 ! MA6D1_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN [Term] id: CCO:C0000380 name: cis-Golgi network namespace: cellular_component def: "The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815316194] synonym: "cis Golgi network" EXACT [] synonym: "forming face" RELATED [] synonym: "Golgi cis face" RELATED [] synonym: "Golgi cis-face" RELATED [] xref: GO:0005801 is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0054320 ! DNM1L_HUMAN relationship: location_of CCO:B0058755 ! MA6D1_HUMAN relationship: location_of CCO:B0064448 ! COG3_HUMAN-Phosphoserine533 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 [Term] id: CCO:C0000381 name: trans-Golgi network namespace: cellular_component def: "The network of interconnected tubular and cisternal structures located at the side of the Golgi apparatus distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination." [GOC:vw, ISBN:0815316194] synonym: "Golgi trans face" RELATED [] synonym: "Golgi trans-face" RELATED [] synonym: "maturing face" RELATED [] synonym: "TGN" EXACT [] synonym: "trans Golgi network" EXACT [] xref: GO:0005802 is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0005950 ! BECN1_HUMAN relationship: location_of CCO:B0026448 ! AT2C1_HUMAN relationship: location_of CCO:B0038438 ! RB11A_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0058975 ! T2R16_HUMAN relationship: location_of CCO:B0059139 ! PCSK1_HUMAN relationship: location_of CCO:B0059339 ! CBY1_HUMAN relationship: location_of CCO:B0061986 ! FOX1A_HUMAN relationship: location_of CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0068447 ! NBEA_HUMAN-Phosphoserine1529 [Term] id: CCO:C0000382 name: lipid particle namespace: cellular_component def: "Any particle of coalesced lipids in the cytoplasm of a cell. May include associated proteins." [GOC:mah] comment: Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers. subset: goslim_generic synonym: "adiposome" EXACT [] synonym: "lipid body" EXACT [] synonym: "lipid droplet" EXACT [] xref: GO:0005811 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0002253 ! STA13_HUMAN relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0063516 ! M6PBP_HUMAN relationship: location_of CCO:B0069547 ! PRP19_HUMAN-Phosphothreonine342 [Term] id: CCO:C0000383 name: centrosome namespace: cellular_component def: "A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle." [GOC:mah, ISBN:0198547684] subset: goslim_pir xref: GO:0005813 is_a: CCO:C0000385 ! microtubule organizing center is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001368 ! CETN3_HUMAN relationship: location_of CCO:B0001408 ! EVI5_HUMAN relationship: location_of CCO:B0001427 ! KTNA1_HUMAN relationship: location_of CCO:B0001440 ! DCTN3_HUMAN relationship: location_of CCO:B0001519 ! CCNB1_HUMAN relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0001577 ! MPIP2_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001649 ! BRCA2_HUMAN relationship: location_of CCO:B0001731 ! CETN1_HUMAN relationship: location_of CCO:B0001918 ! SAS6_HUMAN relationship: location_of CCO:B0001963 ! KIF2B_HUMAN relationship: location_of CCO:B0002056 ! MPPH1_HUMAN relationship: location_of CCO:B0002075 ! NECD_HUMAN relationship: location_of CCO:B0002088 ! Q99773_HUMAN relationship: location_of CCO:B0002099 ! CP250_HUMAN relationship: location_of CCO:B0002100 ! KTNB1_HUMAN relationship: location_of CCO:B0002114 ! Q9BYG9_HUMAN relationship: location_of CCO:B0002162 ! RASF1_HUMAN relationship: location_of CCO:B0002165 ! KIF15_HUMAN relationship: location_of CCO:B0002211 ! TBE_HUMAN relationship: location_of CCO:B0002233 ! CC14A_HUMAN relationship: location_of CCO:B0002242 ! AURKC_HUMAN relationship: location_of CCO:B0002254 ! RBGP1_HUMAN relationship: location_of CCO:B0005244 ! CEP76_HUMAN relationship: location_of CCO:B0005393 ! FEZ1_HUMAN relationship: location_of CCO:B0005426 ! CENPJ_HUMAN relationship: location_of CCO:B0005590 ! CEP63_HUMAN relationship: location_of CCO:B0005591 ! DISC1_HUMAN relationship: location_of CCO:B0006078 ! PCNT_HUMAN relationship: location_of CCO:B0010486 ! AKAP9_HUMAN-Phosphoserine3869 relationship: location_of CCO:B0010567 ! APC_HUMAN-Phosphoserine1038 relationship: location_of CCO:B0011054 ! CDC16_HUMAN-Phosphoserine560 relationship: location_of CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: location_of CCO:B0011130 ! CE110_HUMAN-Phosphoserine641 relationship: location_of CCO:B0011182 ! CETN2_HUMAN-Phosphothreonine26 relationship: location_of CCO:B0011227 ! CK5P2_HUMAN-Phosphotyrosine461 relationship: location_of CCO:B0011243 ! CKAP5_HUMAN-Phosphoserine816 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0011509 ! DHX9_HUMAN-Phosphotyrosine1241 relationship: location_of CCO:B0011767 ! ESPL1_HUMAN-Phosphoserine1508 relationship: location_of CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0012680 ! LATS1_HUMAN-Phosphoserine909 relationship: location_of CCO:B0012723 ! M3K11_HUMAN-Phosphoserine724 relationship: location_of CCO:B0012776 ! MARK4_HUMAN-Phosphoserine26 relationship: location_of CCO:B0012844 ! MD1L1_HUMAN-Phosphoserine214 relationship: location_of CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: location_of CCO:B0013138 ! NDEL1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0013571 ! PLK1_HUMAN-Phosphoserine335 relationship: location_of CCO:B0013654 ! QN1_HUMAN-Phosphoserine776 relationship: location_of CCO:B0013855 ! RGC32_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0013954 ! SAC31_HUMAN-Phosphoserine401 relationship: location_of CCO:B0014304 ! TACC2_HUMAN-Phosphoserine2512 relationship: location_of CCO:B0014698 ! WRN_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: location_of CCO:B0031354 ! NEK2_HUMAN-Phosphoserine390 relationship: location_of CCO:B0035311 ! NTKL_HUMAN-Phosphoserine754 relationship: location_of CCO:B0039949 ! FSD1_HUMAN relationship: location_of CCO:B0041199 ! STK6_HUMAN-Phosphothreonine287 relationship: location_of CCO:B0041297 ! CP110_HUMAN-Phosphothreonine1668 relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: location_of CCO:B0048340 ! NPM_HUMAN-Phosphothreonine279 relationship: location_of CCO:B0054609 ! NPHP4_HUMAN relationship: location_of CCO:B0055869 ! FLII_HUMAN relationship: location_of CCO:B0057222 ! PCGF5_HUMAN relationship: location_of CCO:B0057294 ! CEP57_HUMAN relationship: location_of CCO:B0059189 ! AKA11_HUMAN relationship: location_of CCO:B0062785 ! CEP70_HUMAN relationship: location_of CCO:B0062809 ! HOOK2_HUMAN relationship: location_of CCO:B0062970 ! NIN_HUMAN relationship: location_of CCO:B0063112 ! UXT_HUMAN relationship: location_of CCO:B0063455 ! EPCR_HUMAN relationship: location_of CCO:B0063467 ! OFD1_HUMAN relationship: location_of CCO:B0063496 ! ACTY_HUMAN relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0065695 ! AR2BP_HUMAN-Phosphoserine157 relationship: location_of CCO:B0065850 ! CE350_HUMAN-Phosphoserine1259 relationship: location_of CCO:B0065855 ! CEP72_HUMAN-Phosphoserine237 relationship: location_of CCO:B0065891 ! CPSF5_HUMAN-Phosphotyrosine40 relationship: location_of CCO:B0066277 ! FR1OP_HUMAN-Phosphotyrosine337 relationship: location_of CCO:B0067579 ! LATS2_HUMAN-Phosphoserine380 relationship: location_of CCO:B0069178 ! PDE4D_HUMAN-Phosphoserine18 [Term] id: CCO:C0000384 name: centriole namespace: cellular_component def: "A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle." [ISBN:0198547684] xref: GO:0005814 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001368 ! CETN3_HUMAN relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0011319 ! CNTRB_HUMAN-Phosphoserine781 relationship: location_of CCO:B0011349 ! CROCC_HUMAN-Phosphoserine1619 relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 relationship: part_of CCO:C0000383 ! centrosome [Term] id: CCO:C0000385 name: microtubule organizing center namespace: cellular_component def: "A region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow." [ISBN:0815316194] subset: goslim_candida subset: goslim_generic subset: goslim_yeast synonym: "microtubule organising centre" EXACT [] synonym: "MTOC" EXACT [] xref: GO:0005815 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0002099 ! CP250_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0012464 ! K1C18_HUMAN-Phosphoserine15 relationship: location_of CCO:B0012776 ! MARK4_HUMAN-Phosphoserine26 relationship: location_of CCO:B0031661 ! PAX2_HUMAN relationship: location_of CCO:B0062769 ! EXOC7_HUMAN relationship: location_of CCO:B0065266 ! ABCA2_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: part_of CCO:C0000754 ! microtubule cytoskeleton [Term] id: CCO:C0000386 name: spindle pole body namespace: cellular_component def: "The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome." [ISBN:0879693568] xref: GO:0005816 is_a: CCO:C0000385 ! microtubule organizing center relationship: location_of CCO:B0001395 ! BUB1_HUMAN relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0001731 ! CETN1_HUMAN relationship: part_of CCO:C0000144 ! spindle pole [Term] id: CCO:C0000387 name: aster namespace: cellular_component def: "An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores." [GOC:clt] xref: GO:0005818 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: part_of CCO:C0000388 ! spindle [Term] id: CCO:C0000388 name: spindle namespace: cellular_component def: "The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." [ISBN:0198547684] xref: GO:0005819 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001427 ! KTNA1_HUMAN relationship: location_of CCO:B0001440 ! DCTN3_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001733 ! CDC20_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0001963 ! KIF2B_HUMAN relationship: location_of CCO:B0002003 ! SKA2_HUMAN relationship: location_of CCO:B0002029 ! TP4A1_HUMAN relationship: location_of CCO:B0002032 ! SKA1_HUMAN relationship: location_of CCO:B0002088 ! Q99773_HUMAN relationship: location_of CCO:B0002100 ! KTNB1_HUMAN relationship: location_of CCO:B0002162 ! RASF1_HUMAN relationship: location_of CCO:B0002165 ! KIF15_HUMAN relationship: location_of CCO:B0002221 ! FBX5_HUMAN relationship: location_of CCO:B0005512 ! AKT1_HUMAN relationship: location_of CCO:B0010723 ! AURKB_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0010912 ! CALM_HUMAN-N6,N6,N6-trimethyllysine116 relationship: location_of CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: location_of CCO:B0010965 ! CBX1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0011054 ! CDC16_HUMAN-Phosphoserine560 relationship: location_of CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: location_of CCO:B0011087 ! CDC6_HUMAN-Phosphothreonine166 relationship: location_of CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0012399 ! INCE_HUMAN-Phosphoserine296 relationship: location_of CCO:B0012584 ! KIF11_HUMAN-Phosphothreonine926 relationship: location_of CCO:B0012594 ! KIF23_HUMAN-Phosphoserine682 relationship: location_of CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0012613 ! KNTC1_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0012761 ! MAP9_HUMAN-Phosphoserine132 relationship: location_of CCO:B0012763 ! MARE1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012844 ! MD1L1_HUMAN-Phosphoserine214 relationship: location_of CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: location_of CCO:B0013138 ! NDEL1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0013654 ! QN1_HUMAN-Phosphoserine776 relationship: location_of CCO:B0013804 ! RB_HUMAN-Phosphothreonine826 relationship: location_of CCO:B0013810 ! RCC2_HUMAN-Phosphothreonine20 relationship: location_of CCO:B0013954 ! SAC31_HUMAN-Phosphoserine401 relationship: location_of CCO:B0014164 ! SPAG5_HUMAN-Phosphoserine249 relationship: location_of CCO:B0014528 ! TPX2_HUMAN-Phosphoserine654 relationship: location_of CCO:B0014554 ! TTK_HUMAN-Phosphoserine824 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0041199 ! STK6_HUMAN-Phosphothreonine287 relationship: location_of CCO:B0048362 ! PSRC1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0048400 ! SPIN1_HUMAN-Phosphotyrosine98 relationship: location_of CCO:B0059298 ! INVS_HUMAN relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0065850 ! CE350_HUMAN-Phosphoserine1259 relationship: location_of CCO:B0069906 ! RGAP1_HUMAN-Phosphoserine600 relationship: location_of CCO:B0071340 ! TERF1_HUMAN-Phosphoserine435 relationship: part_of CCO:C0000754 ! microtubule cytoskeleton [Term] id: CCO:C0000389 name: intermediate layer of spindle pole body namespace: cellular_component def: "Structure between the central and outer plaques of the spindle pole body." [PMID:9215630] xref: GO:0005821 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: part_of CCO:C0000386 ! spindle pole body [Term] id: CCO:C0000390 name: inner plaque of spindle pole body namespace: cellular_component def: "One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus." [ISBN:0879693568] xref: GO:0005822 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: part_of CCO:C0000386 ! spindle pole body [Term] id: CCO:C0000391 name: central plaque of spindle pole body namespace: cellular_component def: "One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope." [ISBN:0879693568] xref: GO:0005823 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: part_of CCO:C0000386 ! spindle pole body [Term] id: CCO:C0000392 name: outer plaque of spindle pole body namespace: cellular_component def: "One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm." [ISBN:0879693568] xref: GO:0005824 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: part_of CCO:C0000386 ! spindle pole body [Term] id: CCO:C0000393 name: half bridge of spindle pole body namespace: cellular_component def: "Structure adjacent to the plaques of the spindle pole body." [ISBN:0879693568] xref: GO:0005825 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: part_of CCO:C0000386 ! spindle pole body [Term] id: CCO:C0000394 name: contractile ring namespace: cellular_component def: "A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells. In animal cells, the contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis." [GOC:expert_jrp, GOC:sgd_curators, ISBN:0805319409, ISBN:0815316194] synonym: "actomyosin ring" RELATED [] synonym: "actomyosin ring (sensu Fungi)" NARROW [] synonym: "CAR" EXACT [] synonym: "constriction ring" RELATED [] synonym: "contractile actomyosin ring" EXACT [] synonym: "contractile ring (sensu Fungi)" NARROW [] synonym: "cytokinetic ring (sensu Fungi)" NARROW [] xref: GO:0005826 xref: GO:0030480 is_a: CCO:C0001404 ! cell division site part is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001867 ! cell cortex part relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0002155 ! ANLN_HUMAN relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0000395 name: polar microtubule namespace: cellular_component def: "Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart." [ISBN:0815316194] synonym: "pole-to-pole microtubule" EXACT [] xref: GO:0005827 is_a: CCO:C0000436 ! spindle microtubule relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: part_of CCO:C0000144 ! spindle pole [Term] id: CCO:C0000396 name: kinetochore microtubule namespace: cellular_component def: "Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation." [ISBN:0815316194] synonym: "pole-to-kinetochore microtubule" EXACT [] xref: GO:0005828 is_a: CCO:C0000436 ! spindle microtubule relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0012613 ! KNTC1_HUMAN-Phosphoserine2098 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 [Term] id: CCO:C0000397 name: cytosol namespace: cellular_component def: "That part of the cytoplasm that does not contain membranous or particulate subcellular components." [ISBN:0198547684] subset: goslim_generic subset: goslim_plant subset: gosubset_prok xref: GO:0005829 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0001353 ! PPP6_HUMAN relationship: location_of CCO:B0001354 ! UBE2C_HUMAN relationship: location_of CCO:B0001367 ! AXN1_HUMAN relationship: location_of CCO:B0001396 ! BUB3_HUMAN relationship: location_of CCO:B0001446 ! CCNB2_HUMAN relationship: location_of CCO:B0001457 ! PTTG1_HUMAN relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0001490 ! LCK_HUMAN relationship: location_of CCO:B0001519 ! CCNB1_HUMAN relationship: location_of CCO:B0001523 ! PGDH_HUMAN relationship: location_of CCO:B0001550 ! KTHY_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0001565 ! MK01_HUMAN relationship: location_of CCO:B0001569 ! SHC1_HUMAN relationship: location_of CCO:B0001577 ! MPIP2_HUMAN relationship: location_of CCO:B0001599 ! CDN1A_HUMAN relationship: location_of CCO:B0001600 ! VHL_HUMAN relationship: location_of CCO:B0001610 ! PK3CB_HUMAN relationship: location_of CCO:B0001611 ! FRAP_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001625 ! PSMD8_HUMAN relationship: location_of CCO:B0001691 ! RS4X_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0001701 ! CCNA1_HUMAN relationship: location_of CCO:B0001712 ! MDM2_HUMAN relationship: location_of CCO:B0001723 ! BAX_HUMAN relationship: location_of CCO:B0001733 ! CDC20_HUMAN relationship: location_of CCO:B0001737 ! STRN3_HUMAN relationship: location_of CCO:B0001745 ! PSMD2_HUMAN relationship: location_of CCO:B0001748 ! MD2L1_HUMAN relationship: location_of CCO:B0001759 ! CUL1_HUMAN relationship: location_of CCO:B0002023 ! ARHG1_HUMAN relationship: location_of CCO:B0002027 ! CUL5_HUMAN relationship: location_of CCO:B0002066 ! PSMD1_HUMAN relationship: location_of CCO:B0002177 ! APC11_HUMAN relationship: location_of CCO:B0002213 ! APC7_HUMAN relationship: location_of CCO:B0002215 ! APC4_HUMAN relationship: location_of CCO:B0002221 ! FBX5_HUMAN relationship: location_of CCO:B0002230 ! APC10_HUMAN relationship: location_of CCO:B0002254 ! RBGP1_HUMAN relationship: location_of CCO:B0005170 ! TRAF2_HUMAN relationship: location_of CCO:B0005174 ! NADC_HUMAN relationship: location_of CCO:B0005175 ! BAD_HUMAN relationship: location_of CCO:B0005181 ! UBQL1_HUMAN relationship: location_of CCO:B0005197 ! AP2B1_HUMAN relationship: location_of CCO:B0005216 ! RIPK2_HUMAN relationship: location_of CCO:B0005233 ! PSA1_HUMAN relationship: location_of CCO:B0005316 ! NDK3_HUMAN relationship: location_of CCO:B0005322 ! SMAD4_HUMAN relationship: location_of CCO:B0005338 ! CDC42_HUMAN relationship: location_of CCO:B0005364 ! RUVB2_HUMAN relationship: location_of CCO:B0005409 ! IMB1_HUMAN relationship: location_of CCO:B0005422 ! BID_HUMAN relationship: location_of CCO:B0005479 ! TNR6_HUMAN relationship: location_of CCO:B0005495 ! RUXG_HUMAN relationship: location_of CCO:B0005512 ! AKT1_HUMAN relationship: location_of CCO:B0005520 ! M3K8_HUMAN relationship: location_of CCO:B0005536 ! TRAF6_HUMAN relationship: location_of CCO:B0005571 ! BAT5_HUMAN relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: location_of CCO:B0005586 ! DSS1_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005616 ! PPARG_HUMAN relationship: location_of CCO:B0005617 ! TCP10_HUMAN relationship: location_of CCO:B0005619 ! UBQL4_HUMAN relationship: location_of CCO:B0005633 ! FBW1A_HUMAN relationship: location_of CCO:B0005634 ! SKP1_HUMAN relationship: location_of CCO:B0005667 ! ELOC_HUMAN relationship: location_of CCO:B0005669 ! ELMO1_HUMAN relationship: location_of CCO:B0005671 ! BIRC2_HUMAN relationship: location_of CCO:B0005672 ! TRADD_HUMAN relationship: location_of CCO:B0005679 ! IF4A1_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0005728 ! IF4A2_HUMAN relationship: location_of CCO:B0005744 ! RS19_HUMAN relationship: location_of CCO:B0005746 ! RL7_HUMAN relationship: location_of CCO:B0005750 ! RS9_HUMAN relationship: location_of CCO:B0005751 ! RL22_HUMAN relationship: location_of CCO:B0005761 ! RL7A_HUMAN relationship: location_of CCO:B0005767 ! RS12_HUMAN relationship: location_of CCO:B0005768 ! RS3A_HUMAN relationship: location_of CCO:B0005776 ! RSSA_HUMAN relationship: location_of CCO:B0005857 ! RL15_HUMAN relationship: location_of CCO:B0005858 ! RL11_HUMAN relationship: location_of CCO:B0005859 ! RL27_HUMAN relationship: location_of CCO:B0005860 ! RL8_HUMAN relationship: location_of CCO:B0005861 ! RL4_HUMAN relationship: location_of CCO:B0005892 ! MK11_HUMAN relationship: location_of CCO:B0005912 ! GNDS_HUMAN relationship: location_of CCO:B0006019 ! LPP3_HUMAN relationship: location_of CCO:B0006021 ! IDI2_HUMAN relationship: location_of CCO:B0006067 ! NTF2_HUMAN relationship: location_of CCO:B0006097 ! PNPH_HUMAN relationship: location_of CCO:B0006102 ! IPYR_HUMAN relationship: location_of CCO:B0006108 ! SPB9_HUMAN relationship: location_of CCO:B0006112 ! ST1E1_HUMAN relationship: location_of CCO:B0006114 ! KITH_HUMAN relationship: location_of CCO:B0006143 ! GPDA_HUMAN relationship: location_of CCO:B0006184 ! GLYC_HUMAN relationship: location_of CCO:B0006215 ! PSME1_HUMAN relationship: location_of CCO:B0006219 ! PSB10_HUMAN relationship: location_of CCO:B0006226 ! DYL1_HUMAN relationship: location_of CCO:B0006231 ! RL37A_HUMAN relationship: location_of CCO:B0006232 ! RIR1_HUMAN relationship: location_of CCO:B0006255 ! ABC3G_HUMAN relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0010365 ! 1433B_HUMAN-Phosphoserine186 relationship: location_of CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010436 ! ACSA_HUMAN-Phosphoserine267 relationship: location_of CCO:B0010440 ! ACTB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010481 ! AIP_HUMAN-Phosphotyrosine248 relationship: location_of CCO:B0010521 ! ANC2_HUMAN-Phosphoserine218 relationship: location_of CCO:B0010567 ! APC_HUMAN-Phosphoserine1038 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0010872 ! CABL1_HUMAN-Phosphoserine313 relationship: location_of CCO:B0010887 ! CACB4_HUMAN-Phosphoserine508 relationship: location_of CCO:B0010912 ! CALM_HUMAN-N6,N6,N6-trimethyllysine116 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0010952 ! CBL_HUMAN-Phosphoserine900 relationship: location_of CCO:B0010993 ! CCNE1_HUMAN-Phosphothreonine77 relationship: location_of CCO:B0010997 ! CCNE2_HUMAN-Phosphothreonine392 relationship: location_of CCO:B0011014 ! CD28_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0011054 ! CDC16_HUMAN-Phosphoserine560 relationship: location_of CCO:B0011061 ! CDC23_HUMAN-Phosphothreonine556 relationship: location_of CCO:B0011066 ! CDC26_HUMAN-Phosphoserine78 relationship: location_of CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: location_of CCO:B0011078 ! CDC2_HUMAN-Phosphothreonine14 relationship: location_of CCO:B0011082 ! CDC37_HUMAN-Phosphotyrosine298 relationship: location_of CCO:B0011087 ! CDC6_HUMAN-Phosphothreonine166 relationship: location_of CCO:B0011105 ! CDK2_HUMAN-Phosphotyrosine19 relationship: location_of CCO:B0011112 ! CDK4_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0011126 ! CDN1B_HUMAN-Phosphoserine10 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0011635 ! EF1A1_HUMAN-N6,N6,N6-trimethyllysine36 relationship: location_of CCO:B0011644 ! EF1B_HUMAN-Phosphoserine106 relationship: location_of CCO:B0011648 ! EF1G_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011679 ! ELOB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011697 ! EP15_HUMAN-Phosphoserine324 relationship: location_of CCO:B0011824 ! FAK1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011912 ! FZR_HUMAN-Phosphoserine151 relationship: location_of CCO:B0011973 ! GRB2_HUMAN-Phosphotyrosine160 relationship: location_of CCO:B0012186 ! HGS_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0012302 ! IF2B_HUMAN-Phosphoserine2 relationship: location_of CCO:B0012347 ! IKKA_HUMAN-Phosphothreonine23 relationship: location_of CCO:B0012361 ! IKKB_HUMAN-Phosphoserine733 relationship: location_of CCO:B0012449 ! JUN_HUMAN-Phosphoserine63 relationship: location_of CCO:B0012627 ! KPCA_HUMAN-Phosphoserine657 relationship: location_of CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0012844 ! MD1L1_HUMAN-Phosphoserine214 relationship: location_of CCO:B0012943 ! MK03_HUMAN-Phosphotyrosine204 relationship: location_of CCO:B0012953 ! MK08_HUMAN-Phosphoserine377 relationship: location_of CCO:B0012974 ! MP2K1_HUMAN-Phosphoserine218 relationship: location_of CCO:B0013164 ! NFKB2_HUMAN-Phosphoserine713 relationship: location_of CCO:B0013372 ! PABP1_HUMAN-Omega-N-methylated arginine493 relationship: location_of CCO:B0013450 ! PDCD4_HUMAN-Phosphoserine76 relationship: location_of CCO:B0013468 ! PDLI5_HUMAN-Phosphoserine136 relationship: location_of CCO:B0013478 ! PDPK1_HUMAN-Phosphoserine241 relationship: location_of CCO:B0013496 ! PGAM1_HUMAN-Phosphotyrosine26 relationship: location_of CCO:B0013567 ! PLCG1_HUMAN-Phosphotyrosine1253 relationship: location_of CCO:B0013571 ! PLK1_HUMAN-Phosphoserine335 relationship: location_of CCO:B0013601 ! PPIA_HUMAN-Phosphoserine21 relationship: location_of CCO:B0013617 ! PRS4_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0013620 ! PSA3_HUMAN-Phosphotyrosine161 relationship: location_of CCO:B0013641 ! PTEN_HUMAN-Phosphoserine370 relationship: location_of CCO:B0013659 ! RAC1_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0013681 ! RAF1_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013709 ! RAP1A_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0013875 ! RIPK1_HUMAN-Phosphotyrosine384 relationship: location_of CCO:B0013882 ! RL12_HUMAN-Phosphoserine38 relationship: location_of CCO:B0013884 ! RL18A_HUMAN-Phosphotyrosine63 relationship: location_of CCO:B0013886 ! RL18_HUMAN-Phosphoserine130 relationship: location_of CCO:B0013888 ! RL24_HUMAN-Phosphoserine86 relationship: location_of CCO:B0013889 ! RL28_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013896 ! RLA0_HUMAN-Phosphotyrosine24 relationship: location_of CCO:B0013900 ! RLA1_HUMAN-Phosphotyrosine11 relationship: location_of CCO:B0013905 ! RLA2_HUMAN-Phosphoserine102 relationship: location_of CCO:B0013932 ! RS10_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0013936 ! RS13_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013939 ! RS20_HUMAN-Phosphothreonine9 relationship: location_of CCO:B0013940 ! RS24_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013943 ! RS7_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0014054 ! SH3G2_HUMAN-Phosphoserine75 relationship: location_of CCO:B0014148 ! SNUT1_HUMAN-Phosphoserine596 relationship: location_of CCO:B0014318 ! TBK1_HUMAN-Phosphoserine172 relationship: location_of CCO:B0014323 ! TCPB_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0014351 ! THIO_HUMAN-Phosphothreonine100 relationship: location_of CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0014564 ! UBE3A_HUMAN-Phosphoserine218 relationship: location_of CCO:B0014714 ! XPO1_HUMAN-Phosphoserine397 relationship: location_of CCO:B0015270 ! DFFB_HUMAN relationship: location_of CCO:B0015288 ! ARF1_HUMAN relationship: location_of CCO:B0016186 ! IF4E_HUMAN relationship: location_of CCO:B0016299 ! PP2BC_HUMAN relationship: location_of CCO:B0016326 ! AAKG2_HUMAN relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0017902 ! RBM38_HUMAN relationship: location_of CCO:B0018189 ! PYDC1_HUMAN relationship: location_of CCO:B0018350 ! PK3CA_HUMAN relationship: location_of CCO:B0018508 ! HXK4_HUMAN relationship: location_of CCO:B0018778 ! M3K12_HUMAN relationship: location_of CCO:B0019462 ! UB2D1_HUMAN relationship: location_of CCO:B0020771 ! RGS3_HUMAN relationship: location_of CCO:B0020777 ! RGS13_HUMAN relationship: location_of CCO:B0021069 ! EF1D_HUMAN relationship: location_of CCO:B0021560 ! PSMD3_HUMAN relationship: location_of CCO:B0022204 ! PSA5_HUMAN relationship: location_of CCO:B0023192 ! SMD1_HUMAN relationship: location_of CCO:B0023606 ! PSDE_HUMAN relationship: location_of CCO:B0024182 ! RPIA_HUMAN relationship: location_of CCO:B0024484 ! PLCB3_HUMAN relationship: location_of CCO:B0025070 ! PDZD3_HUMAN relationship: location_of CCO:B0026267 ! DHB14_HUMAN relationship: location_of CCO:B0026277 ! EIF3F_HUMAN relationship: location_of CCO:B0026356 ! EIF3B_HUMAN-Phosphotyrosine525 relationship: location_of CCO:B0026366 ! EIF3D_HUMAN-Phosphotyrosine318 relationship: location_of CCO:B0026369 ! EIF3E_HUMAN-Phosphothreonine439 relationship: location_of CCO:B0026372 ! EIF3G_HUMAN-Phosphoserine42 relationship: location_of CCO:B0026373 ! EIF3I_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0026377 ! EIF3K_HUMAN-Phosphoserine217 relationship: location_of CCO:B0026912 ! PEX6_HUMAN relationship: location_of CCO:B0027730 ! SIN1_HUMAN relationship: location_of CCO:B0029351 ! EGLN1_HUMAN relationship: location_of CCO:B0029592 ! RL36_HUMAN relationship: location_of CCO:B0030301 ! PRPS1_HUMAN relationship: location_of CCO:B0030465 ! RS23_HUMAN relationship: location_of CCO:B0030757 ! RIR2_HUMAN relationship: location_of CCO:B0030804 ! PSB8_HUMAN relationship: location_of CCO:B0030806 ! PSB5_HUMAN relationship: location_of CCO:B0030810 ! Q5JNW7_HUMAN relationship: location_of CCO:B0030929 ! PSB3_HUMAN relationship: location_of CCO:B0031007 ! PSB9_HUMAN relationship: location_of CCO:B0031015 ! PSB6_HUMAN relationship: location_of CCO:B0031331 ! HS90A_HUMAN-Phosphotyrosine313 relationship: location_of CCO:B0031354 ! NEK2_HUMAN-Phosphoserine390 relationship: location_of CCO:B0031369 ! PTN6_HUMAN-Phosphotyrosine377 relationship: location_of CCO:B0031622 ! CDD_HUMAN relationship: location_of CCO:B0032651 ! PSMD6_HUMAN relationship: location_of CCO:B0032819 ! ASNS_HUMAN relationship: location_of CCO:B0033001 ! RS27_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0033633 ! RL13_HUMAN relationship: location_of CCO:B0034007 ! PSB7_HUMAN relationship: location_of CCO:B0034271 ! RS25_HUMAN relationship: location_of CCO:B0034557 ! ANXA9_HUMAN-Phosphoserine2 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0034772 ! F261_HUMAN-Phosphoserine33 relationship: location_of CCO:B0034845 ! GSK3B_HUMAN-Phosphoserine215 relationship: location_of CCO:B0034952 ! K6PF_HUMAN-Phosphothreonine2 relationship: location_of CCO:B0034954 ! K6PL_HUMAN-Phosphotyrosine633 relationship: location_of CCO:B0035014 ! KCRB_HUMAN-Phosphoserine164 relationship: location_of CCO:B0035046 ! KPCB_HUMAN-Phosphothreonine504 relationship: location_of CCO:B0035064 ! KPCG_HUMAN-Phosphoserine687 relationship: location_of CCO:B0035087 ! LANC2_HUMAN-Phosphotyrosine295 relationship: location_of CCO:B0035198 ! MK14_HUMAN-Phosphotyrosine182 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0035477 ! PSA7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0035478 ! PSB1_HUMAN-Phosphotyrosine150 relationship: location_of CCO:B0035479 ! PSB2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035483 ! PSD7_HUMAN-Phosphothreonine186 relationship: location_of CCO:B0035539 ! RD23B_HUMAN-Phosphoserine160 relationship: location_of CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: location_of CCO:B0035772 ! TERA_HUMAN-Phosphotyrosine805 relationship: location_of CCO:B0035785 ! TISB_HUMAN-Phosphoserine54 relationship: location_of CCO:B0035812 ! TPIS_HUMAN-Phosphoserine21 relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0036005 ! FOXO4_HUMAN-Phosphoserine111 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0036028 ! RL21_HUMAN-Phosphothreonine47 relationship: location_of CCO:B0036957 ! HPRT_HUMAN relationship: location_of CCO:B0038095 ! ABI2_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039463 ! IF5A1_HUMAN-Blocked amino end (Ala)2 relationship: location_of CCO:B0039467 ! IF5A2_HUMAN-Hypusine50 relationship: location_of CCO:B0039472 ! IMA1_HUMAN-Phosphothreonine3 relationship: location_of CCO:B0039492 ! M3K7_HUMAN-Phosphoserine439 relationship: location_of CCO:B0039596 ! PREX1_HUMAN-Phosphoserine436 relationship: location_of CCO:B0039597 ! PRS10_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039598 ! PSD12_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039640 ! RPGF1_HUMAN-Phosphoserine360 relationship: location_of CCO:B0039654 ! SPHK2_HUMAN-Phosphoserine399 relationship: location_of CCO:B0039670 ! TALDO_HUMAN-Phosphoserine237 relationship: location_of CCO:B0039700 ! TTP_HUMAN-Phosphoserine323 relationship: location_of CCO:B0039936 ! RHEB_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0040018 ! GNPAT_HUMAN relationship: location_of CCO:B0040516 ! RS14_HUMAN relationship: location_of CCO:B0040650 ! PUR2_HUMAN-Phosphotyrosine348 relationship: location_of CCO:B0041114 ! APC1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0041125 ! APC5_HUMAN-Phosphoserine217 relationship: location_of CCO:B0041145 ! IKBA_HUMAN-Phosphoserine283 relationship: location_of CCO:B0041151 ! IKBB_HUMAN-Phosphoserine315 relationship: location_of CCO:B0041164 ! NEMO_HUMAN-Phosphoserine43 relationship: location_of CCO:B0041168 ! OGT1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041207 ! TF65_HUMAN-N6-acetyllysine122 relationship: location_of CCO:B0041239 ! PSMD9_HUMAN relationship: location_of CCO:B0041243 ! PSA2_HUMAN relationship: location_of CCO:B0041244 ! PSA4_HUMAN relationship: location_of CCO:B0041245 ! PSB4_HUMAN relationship: location_of CCO:B0041246 ! PRS7_HUMAN relationship: location_of CCO:B0041247 ! PRS6B_HUMAN relationship: location_of CCO:B0041248 ! UB2E1_HUMAN relationship: location_of CCO:B0041251 ! PSA6_HUMAN relationship: location_of CCO:B0041252 ! PSME3_HUMAN relationship: location_of CCO:B0041253 ! PRS8_HUMAN relationship: location_of CCO:B0041255 ! PSMD5_HUMAN relationship: location_of CCO:B0041301 ! EIF3J_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041305 ! HBXIP_HUMAN-Phosphoserine26 relationship: location_of CCO:B0041315 ! PRS6A_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041328 ! PSD10_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041333 ! PSMD4_HUMAN-Phosphoserine358 relationship: location_of CCO:B0041339 ! RBX1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041672 ! BNIPL_HUMAN relationship: location_of CCO:B0043290 ! IF2A_HUMAN-Phosphoserine49 relationship: location_of CCO:B0043438 ! RUXF_HUMAN relationship: location_of CCO:B0043492 ! RSMB_HUMAN-Omega-N-methylated arginine112 relationship: location_of CCO:B0043592 ! RL23_HUMAN relationship: location_of CCO:B0043610 ! F16P1_HUMAN relationship: location_of CCO:B0043825 ! RS15A_HUMAN relationship: location_of CCO:B0043869 ! U119A_HUMAN relationship: location_of CCO:B0048182 ! CCND1_HUMAN-Phosphotyrosine226 relationship: location_of CCO:B0048312 ! M3K1_HUMAN-Phosphoserine292 relationship: location_of CCO:B0048404 ! TAB1_HUMAN-Phosphoserine7 relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0050696 ! IDHC_HUMAN relationship: location_of CCO:B0050997 ! MFN2_HUMAN relationship: location_of CCO:B0051549 ! IF5_HUMAN relationship: location_of CCO:B0052399 ! GBRL2_HUMAN-Phosphoserine10 relationship: location_of CCO:B0052404 ! GELS_HUMAN-Phosphotyrosine603 relationship: location_of CCO:B0052434 ! IF4B_HUMAN-Phosphoserine422 relationship: location_of CCO:B0052719 ! S10A7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054342 ! ACACB_HUMAN relationship: location_of CCO:B0054344 ! LPP1_HUMAN relationship: location_of CCO:B0054370 ! ITBP1_HUMAN relationship: location_of CCO:B0054371 ! APAF_HUMAN relationship: location_of CCO:B0054391 ! GIPC1_HUMAN relationship: location_of CCO:B0054406 ! SMAD7_HUMAN relationship: location_of CCO:B0054414 ! SMAD9_HUMAN relationship: location_of CCO:B0054488 ! SMAD6_HUMAN relationship: location_of CCO:B0054499 ! SPY1_HUMAN relationship: location_of CCO:B0054526 ! NRDC_HUMAN relationship: location_of CCO:B0054591 ! NOL3_HUMAN relationship: location_of CCO:B0054668 ! GRAP2_HUMAN relationship: location_of CCO:B0054676 ! RASF9_HUMAN relationship: location_of CCO:B0054690 ! S14L2_HUMAN relationship: location_of CCO:B0054758 ! ZFYV9_HUMAN relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: location_of CCO:B0054797 ! DCMC_HUMAN relationship: location_of CCO:B0054801 ! DDAH2_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054893 ! TYSY_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0054950 ! TACD2_HUMAN relationship: location_of CCO:B0054971 ! GRAB_HUMAN relationship: location_of CCO:B0054997 ! DCOR_HUMAN relationship: location_of CCO:B0054998 ! IMDH2_HUMAN relationship: location_of CCO:B0055025 ! ENPL_HUMAN relationship: location_of CCO:B0055097 ! LOX12_HUMAN relationship: location_of CCO:B0055112 ! TYPH_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055266 ! DUT_HUMAN relationship: location_of CCO:B0055351 ! CASP3_HUMAN relationship: location_of CCO:B0055404 ! GSH1_HUMAN relationship: location_of CCO:B0055405 ! GSH0_HUMAN relationship: location_of CCO:B0055410 ! KC1A_HUMAN relationship: location_of CCO:B0055421 ! FNTA_HUMAN relationship: location_of CCO:B0055423 ! DHYS_HUMAN relationship: location_of CCO:B0055510 ! AP2S1_HUMAN relationship: location_of CCO:B0055530 ! CASP7_HUMAN relationship: location_of CCO:B0055717 ! RL6_HUMAN relationship: location_of CCO:B0055765 ! PTN11_HUMAN relationship: location_of CCO:B0055919 ! Q13502_HUMAN relationship: location_of CCO:B0055954 ! RGRF1_HUMAN relationship: location_of CCO:B0056009 ! IRF3_HUMAN relationship: location_of CCO:B0056127 ! ENOX2_HUMAN relationship: location_of CCO:B0056166 ! MAPK3_HUMAN relationship: location_of CCO:B0056547 ! ARH_HUMAN relationship: location_of CCO:B0056666 ! Q5VXI4_HUMAN relationship: location_of CCO:B0057321 ! TCAM1_HUMAN relationship: location_of CCO:B0057589 ! PK3C3_HUMAN relationship: location_of CCO:B0057992 ! CPLX3_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058093 ! STAM1_HUMAN relationship: location_of CCO:B0058121 ! TNR25_HUMAN relationship: location_of CCO:B0058147 ! RERG_HUMAN relationship: location_of CCO:B0058155 ! CIDEC_HUMAN relationship: location_of CCO:B0058276 ! BINCA_HUMAN relationship: location_of CCO:B0058311 ! AIFM3_HUMAN relationship: location_of CCO:B0058488 ! TXD17_HUMAN relationship: location_of CCO:B0058494 ! AIFM2_HUMAN relationship: location_of CCO:B0058559 ! CAR11_HUMAN relationship: location_of CCO:B0058605 ! B2L14_HUMAN relationship: location_of CCO:B0058795 ! NOD2_HUMAN relationship: location_of CCO:B0058800 ! CAN10_HUMAN relationship: location_of CCO:B0058862 ! ISK5_HUMAN relationship: location_of CCO:B0058884 ! DBLOH_HUMAN relationship: location_of CCO:B0058931 ! RIC8B_HUMAN relationship: location_of CCO:B0058944 ! IRAK4_HUMAN relationship: location_of CCO:B0058995 ! SPG21_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059106 ! MALT1_HUMAN relationship: location_of CCO:B0062779 ! PHP14_HUMAN relationship: location_of CCO:B0062812 ! DYL2_HUMAN relationship: location_of CCO:B0062824 ! AP2M1_HUMAN relationship: location_of CCO:B0062885 ! RL9_HUMAN relationship: location_of CCO:B0062915 ! NCALD_HUMAN relationship: location_of CCO:B0062961 ! MTHFS_HUMAN relationship: location_of CCO:B0062968 ! VPS28_HUMAN relationship: location_of CCO:B0062979 ! GEMI5_HUMAN relationship: location_of CCO:B0062984 ! LEG4_HUMAN relationship: location_of CCO:B0062986 ! VPS4A_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0063016 ! NCBP2_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0063048 ! RL35A_HUMAN relationship: location_of CCO:B0063061 ! RS5_HUMAN relationship: location_of CCO:B0063078 ! RS16_HUMAN relationship: location_of CCO:B0063080 ! TCPA_HUMAN relationship: location_of CCO:B0063083 ! RL3_HUMAN relationship: location_of CCO:B0063091 ! RL35_HUMAN relationship: location_of CCO:B0063093 ! RL10_HUMAN relationship: location_of CCO:B0063103 ! PFD4_HUMAN relationship: location_of CCO:B0063160 ! COMT_HUMAN relationship: location_of CCO:B0063204 ! AP1B1_HUMAN relationship: location_of CCO:B0063245 ! GCKR_HUMAN relationship: location_of CCO:B0063258 ! VPS35_HUMAN relationship: location_of CCO:B0063284 ! GYS1_HUMAN relationship: location_of CCO:B0063353 ! RS26_HUMAN relationship: location_of CCO:B0063356 ! RL27A_HUMAN relationship: location_of CCO:B0063360 ! RL23A_HUMAN relationship: location_of CCO:B0063368 ! RS28_HUMAN relationship: location_of CCO:B0063415 ! GEMI7_HUMAN relationship: location_of CCO:B0063418 ! PPA5_HUMAN relationship: location_of CCO:B0063430 ! RIFK_HUMAN relationship: location_of CCO:B0063474 ! RS2_HUMAN relationship: location_of CCO:B0063493 ! PYR5_HUMAN relationship: location_of CCO:B0063598 ! ARMS_HUMAN-Phosphoserine918 relationship: location_of CCO:B0063652 ! ATF2_HUMAN-Phosphothreonine71 relationship: location_of CCO:B0063701 ! BAG3_HUMAN-Phosphothreonine285 relationship: location_of CCO:B0063920 ! BIG2_HUMAN-Phosphoserine1514 relationship: location_of CCO:B0063924 ! BIM_HUMAN-Phosphoserine77 relationship: location_of CCO:B0063925 ! BIRC4_HUMAN-Phosphoserine87 relationship: location_of CCO:B0064045 ! CACB3_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0064058 ! CANB1_HUMAN-Phosphotyrosine106 relationship: location_of CCO:B0064079 ! CASP8_HUMAN-Phosphotyrosine334 relationship: location_of CCO:B0064082 ! CASP9_HUMAN-Phosphoserine307 relationship: location_of CCO:B0064355 ! CIDEB_HUMAN-Phosphoserine17 relationship: location_of CCO:B0064473 ! CRK_HUMAN-Phosphoserine41 relationship: location_of CCO:B0064607 ! CYC_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: location_of CCO:B0064744 ! DFFA_HUMAN-Phosphoserine315 relationship: location_of CCO:B0064751 ! DGKA_HUMAN-Phosphotyrosine22 relationship: location_of CCO:B0064954 ! EIF3A_HUMAN-Phosphoserine584 relationship: location_of CCO:B0064963 ! EIF3C_HUMAN-Phosphoserine15 relationship: location_of CCO:B0064970 ! EIF3H_HUMAN-Phosphoserine183 relationship: location_of CCO:B0065190 ! FABP6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065191 ! FADD_HUMAN-Phosphoserine194 relationship: location_of CCO:B0065208 ! 4EBP1_HUMAN-Phosphotyrosine54 relationship: location_of CCO:B0065241 ! AAKB2_HUMAN-Phosphoserine183 relationship: location_of CCO:B0065258 ! AAPK2_HUMAN-Phosphoserine173 relationship: location_of CCO:B0065340 ! ACINU_HUMAN-Phosphothreonine414 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0065403 ! ADA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065435 ! ADPPT_HUMAN-Phosphoserine258 relationship: location_of CCO:B0065578 ! AKT2_HUMAN-Phosphoserine126 relationship: location_of CCO:B0065581 ! AKTS1_HUMAN-Phosphoserine116 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0065658 ! AP1M1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: location_of CCO:B0065705 ! ARFG3_HUMAN-Phosphoserine143 relationship: location_of CCO:B0065743 ! ARHG7_HUMAN-Phosphoserine176 relationship: location_of CCO:B0065798 ! BL1S1_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0065925 ! DCTD_HUMAN-Phosphotyrosine79 relationship: location_of CCO:B0065958 ! DOCK2_HUMAN-Phosphoserine1706 relationship: location_of CCO:B0066025 ! ERG19_HUMAN-Phosphoserine96 relationship: location_of CCO:B0066061 ! F16P2_HUMAN-Phosphotyrosine216 relationship: location_of CCO:B0066115 ! FAF1_HUMAN-Phosphothreonine580 relationship: location_of CCO:B0066134 ! FAS_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0066324 ! FYN_HUMAN-Phosphotyrosine213 relationship: location_of CCO:B0066357 ! GAB1_HUMAN-Phosphotyrosine406 relationship: location_of CCO:B0066377 ! GAPD1_HUMAN-Phosphoserine966 relationship: location_of CCO:B0066433 ! GDE_HUMAN-Phosphotyrosine584 relationship: location_of CCO:B0066440 ! GEMI2_HUMAN-Phosphothreonine48 relationship: location_of CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 relationship: location_of CCO:B0066575 ! GPX1_HUMAN-N6-acetyllysine146 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0066824 ! HMGA1_HUMAN-Phosphoserine36 relationship: location_of CCO:B0066839 ! HMOX1_HUMAN-Phosphoserine229 relationship: location_of CCO:B0066966 ! HXK1_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0067002 ! ICLN_HUMAN-Phosphoserine102 relationship: location_of CCO:B0067036 ! IF4G1_HUMAN-Phosphoserine1210 relationship: location_of CCO:B0067049 ! IF4H_HUMAN-Phosphoserine193 relationship: location_of CCO:B0067152 ! IRAK1_HUMAN-Phosphoserine568 relationship: location_of CCO:B0067163 ! ITK_HUMAN-Phosphoserine565 relationship: location_of CCO:B0067418 ! KPCD_HUMAN-Phosphoserine307 relationship: location_of CCO:B0067435 ! KPYM_HUMAN-Phosphotyrosine83 relationship: location_of CCO:B0067487 ! KS6B1_HUMAN-Phosphoserine441 relationship: location_of CCO:B0067601 ! LCP2_HUMAN-Phosphotyrosine23 relationship: location_of CCO:B0067605 ! LDHA_HUMAN-Phosphotyrosine239 relationship: location_of CCO:B0067928 ! MAP1B_HUMAN-Phosphotyrosine1974 relationship: location_of CCO:B0067985 ! MAPK2_HUMAN-Phosphoserine328 relationship: location_of CCO:B0068055 ! MCF2_HUMAN-Phosphoserine742 relationship: location_of CCO:B0068111 ! MDHC_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0068256 ! MPIP3_HUMAN-Phosphoserine57 relationship: location_of CCO:B0068438 ! NAMPT_HUMAN-Phosphotyrosine34 relationship: location_of CCO:B0068447 ! NBEA_HUMAN-Phosphoserine1529 relationship: location_of CCO:B0068452 ! NCBP1_HUMAN-Phosphoserine22 relationship: location_of CCO:B0068457 ! NCF1_HUMAN-Phosphoserine304 relationship: location_of CCO:B0068667 ! NFKB1_HUMAN-Phosphoserine907 relationship: location_of CCO:B0068985 ! ORC1_HUMAN-Phosphothreonine337 relationship: location_of CCO:B0069034 ! P85A_HUMAN-Phosphotyrosine467 relationship: location_of CCO:B0069040 ! P85B_HUMAN-Phosphotyrosine467 relationship: location_of CCO:B0069042 ! PA24C_HUMAN-Cysteine methyl ester538 relationship: location_of CCO:B0069065 ! PAK2_HUMAN-Phosphoserine58 relationship: location_of CCO:B0069148 ! PBIP1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0069419 ! PLSL_HUMAN-Phosphotyrosine28 relationship: location_of CCO:B0069574 ! PSIP1_HUMAN-Phosphoserine177 relationship: location_of CCO:B0069579 ! PSMF1_HUMAN-Phosphoserine252 relationship: location_of CCO:B0069649 ! PYR1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0070063 ! RL14_HUMAN-Phosphoserine139 relationship: location_of CCO:B0070079 ! RL26_HUMAN-Phosphothreonine139 relationship: location_of CCO:B0070080 ! RL29_HUMAN-N6-methyllysine5 relationship: location_of CCO:B0070084 ! RL31_HUMAN-Phosphotyrosine108 relationship: location_of CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 relationship: location_of CCO:B0070132 ! ROCK1_HUMAN-Phosphothreonine1180 relationship: location_of CCO:B0070197 ! RRP5_HUMAN-Phosphoserine1360 relationship: location_of CCO:B0070200 ! RS11_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 relationship: location_of CCO:B0070222 ! RS8_HUMAN-Phosphothreonine130 relationship: location_of CCO:B0070505 ! SHIP1_HUMAN-Phosphotyrosine944 relationship: location_of CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0070598 ! SMAD2_HUMAN-Phosphoserine255 relationship: location_of CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 relationship: location_of CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 relationship: location_of CCO:B0070644 ! SMD2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070647 ! SMN_HUMAN-Phosphothreonine25 relationship: location_of CCO:B0070746 ! SOS1_HUMAN-Phosphoserine1134 relationship: location_of CCO:B0070798 ! SPHK1_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0070821 ! SPTA2_HUMAN-Phosphoserine1217 relationship: location_of CCO:B0070846 ! SQSTM_HUMAN-Phosphoserine170 relationship: location_of CCO:B0070904 ! SRC_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0070960 ! STAM2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0071075 ! TAB2_HUMAN-Phosphoserine372 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0071447 ! TOM1_HUMAN-Phosphoserine176 relationship: location_of CCO:B0071574 ! TRIPC_HUMAN-Phosphoserine997 relationship: location_of CCO:B0071591 ! TRXR1_HUMAN-Phosphotyrosine163 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: location_of CCO:B0071730 ! ULK1_HUMAN-Phosphothreonine625 relationship: location_of CCO:B0071888 ! XDH_HUMAN-Phosphothreonine222 relationship: location_of CCO:B0071895 ! XRCC4_HUMAN-Phosphoserine327 relationship: location_of CCO:B0071950 ! ZAP70_HUMAN-Phosphotyrosine315 relationship: location_of CCO:B0072004 ! ZF106_HUMAN-Phosphoserine1026 [Term] id: CCO:C0000399 name: steroid hormone aporeceptor complex namespace: cellular_component def: "A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand." [PMID:7493981] xref: GO:0005831 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0000400 name: chaperonin-containing T-complex namespace: cellular_component def: "A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor." [GOC:sgd_curators, PMID:11580267] synonym: "CCT particle" EXACT [] synonym: "TriC" EXACT [] xref: GO:0005832 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0001648 ! TCPD_HUMAN relationship: location_of CCO:B0002089 ! TCPH_HUMAN relationship: location_of CCO:B0014323 ! TCPB_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041344 ! TCPE_HUMAN-N-acetylalanine2 [Term] id: CCO:C0000401 name: hemoglobin complex namespace: cellular_component def: "An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "haemoglobin complex" EXACT [] xref: GO:0005833 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0058994 ! AHSP_HUMAN relationship: location_of CCO:B0066757 ! HBAZ_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066758 ! HBA_HUMAN-Phosphotyrosine25 relationship: location_of CCO:B0066763 ! HBB_HUMAN-Phosphotyrosine131 [Term] id: CCO:C0000402 name: heterotrimeric G-protein complex namespace: cellular_component def: "Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein." [ISBN:0198547684] comment: See also the molecular function term 'G-protein coupled receptor activity ; GO:0004930'. subset: gosubset_prok synonym: "heterotrimeric G-protein GTPase activity" RELATED [] synonym: "heterotrimeric G-protein GTPase, alpha-subunit" NARROW [] synonym: "heterotrimeric G-protein GTPase, beta-subunit" NARROW [] synonym: "heterotrimeric G-protein GTPase, gamma-subunit" NARROW [] xref: GO:0005834 is_a: CCO:C0000899 ! extrinsic to plasma membrane is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0006142 ! GBB5_HUMAN relationship: location_of CCO:B0011949 ! GNAI1_HUMAN-ADP-ribosylarginine178 relationship: location_of CCO:B0027558 ! Q14455_HUMAN relationship: location_of CCO:B0035557 ! RGS19_HUMAN-Phosphoserine24 relationship: location_of CCO:B0052407 ! GNA14_HUMAN-ADP-ribosylarginine179 relationship: location_of CCO:B0052417 ! GNAT2_HUMAN-ADP-ribosylcysteine351 relationship: location_of CCO:B0053782 ! A6NC00_HUMAN relationship: location_of CCO:B0053962 ! A8K3C0_HUMAN relationship: location_of CCO:B0054356 ! GBGT2_HUMAN relationship: location_of CCO:B0054537 ! GBG7_HUMAN relationship: location_of CCO:B0054678 ! RGS9_HUMAN relationship: location_of CCO:B0054700 ! RGS11_HUMAN relationship: location_of CCO:B0054765 ! GNAS3_HUMAN relationship: location_of CCO:B0055433 ! RGS6_HUMAN relationship: location_of CCO:B0055443 ! GBG4_HUMAN relationship: location_of CCO:B0055444 ! GBG10_HUMAN relationship: location_of CCO:B0055614 ! GBG11_HUMAN relationship: location_of CCO:B0055631 ! GBG1_HUMAN relationship: location_of CCO:B0055632 ! GBG3_HUMAN relationship: location_of CCO:B0055633 ! GBG5_HUMAN relationship: location_of CCO:B0055981 ! Q14396_HUMAN relationship: location_of CCO:B0056323 ! Q4TT72_HUMAN relationship: location_of CCO:B0056568 ! Q5T3H4_HUMAN relationship: location_of CCO:B0056569 ! Q5T3H5_HUMAN relationship: location_of CCO:B0057554 ! Q8NB18_HUMAN relationship: location_of CCO:B0058168 ! Q96BN9_HUMAN relationship: location_of CCO:B0059061 ! GBG13_HUMAN relationship: location_of CCO:B0059182 ! GBG8_HUMAN relationship: location_of CCO:B0059337 ! GBG5L_HUMAN relationship: location_of CCO:B0063615 ! ARRB1_HUMAN-Phosphothreonine410 relationship: location_of CCO:B0066399 ! GBG12_HUMAN-Phosphotyrosine42 relationship: location_of CCO:B0066401 ! GBG2_HUMAN-Phosphothreonine52 relationship: location_of CCO:B0066484 ! GNA15_HUMAN-ADP-ribosylarginine186 relationship: location_of CCO:B0066490 ! GNAS2_HUMAN-Phosphoserine51 relationship: location_of CCO:B0069922 ! RGS7_HUMAN-Phosphoserine229 [Term] id: CCO:C0000403 name: fatty acid synthase complex namespace: cellular_component def: "A multienzyme complex required to convert carbohydrates to fatty acids, specifically acetyl CoA to palmitate." [GOC:sgd_curators, ISBN:0716746840] subset: goslim_pir subset: gosubset_prok synonym: "FAS complex" EXACT [] synonym: "holo-[acyl-carrier-protein] synthase complex" RELATED [] xref: GO:0005835 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000404 name: fatty-acyl-CoA synthase complex namespace: cellular_component def: "A protein complex that possesses fatty-acyl-CoA synthase activity." [BRENDA:2.3.1.86, GOC:mah] comment: Note that fatty acid synthetases of vertebrates and yeast are stable enzyme complexes of multifunctional polypeptide chains, whereas the fatty acid synthetases of plants and E. coli consist of non-associated individual enzymes. xref: GO:0005836 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0000407 name: ribosome namespace: cellular_component def: "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "ribosomal RNA" RELATED [] xref: GO:0005840 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001691 ! RS4X_HUMAN relationship: location_of CCO:B0001952 ! RM41_HUMAN relationship: location_of CCO:B0002153 ! CYLD_HUMAN relationship: location_of CCO:B0005744 ! RS19_HUMAN relationship: location_of CCO:B0005746 ! RL7_HUMAN relationship: location_of CCO:B0005750 ! RS9_HUMAN relationship: location_of CCO:B0005751 ! RL22_HUMAN relationship: location_of CCO:B0005761 ! RL7A_HUMAN relationship: location_of CCO:B0005767 ! RS12_HUMAN relationship: location_of CCO:B0005768 ! RS3A_HUMAN relationship: location_of CCO:B0005776 ! RSSA_HUMAN relationship: location_of CCO:B0005855 ! RL12_HUMAN relationship: location_of CCO:B0005857 ! RL15_HUMAN relationship: location_of CCO:B0005858 ! RL11_HUMAN relationship: location_of CCO:B0005859 ! RL27_HUMAN relationship: location_of CCO:B0005860 ! RL8_HUMAN relationship: location_of CCO:B0005861 ! RL4_HUMAN relationship: location_of CCO:B0006095 ! RT12_HUMAN relationship: location_of CCO:B0006208 ! RT06_HUMAN relationship: location_of CCO:B0006231 ! RL37A_HUMAN relationship: location_of CCO:B0006248 ! RM20_HUMAN relationship: location_of CCO:B0006288 ! RT26_HUMAN relationship: location_of CCO:B0013882 ! RL12_HUMAN-Phosphoserine38 relationship: location_of CCO:B0013884 ! RL18A_HUMAN-Phosphotyrosine63 relationship: location_of CCO:B0013886 ! RL18_HUMAN-Phosphoserine130 relationship: location_of CCO:B0013888 ! RL24_HUMAN-Phosphoserine86 relationship: location_of CCO:B0013889 ! RL28_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013896 ! RLA0_HUMAN-Phosphotyrosine24 relationship: location_of CCO:B0013900 ! RLA1_HUMAN-Phosphotyrosine11 relationship: location_of CCO:B0013905 ! RLA2_HUMAN-Phosphoserine102 relationship: location_of CCO:B0013932 ! RS10_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0013936 ! RS13_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013939 ! RS20_HUMAN-Phosphothreonine9 relationship: location_of CCO:B0013940 ! RS24_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013943 ! RS7_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0028628 ! Q7Z721_HUMAN relationship: location_of CCO:B0029592 ! RL36_HUMAN relationship: location_of CCO:B0030465 ! RS23_HUMAN relationship: location_of CCO:B0033001 ! RS27_HUMAN relationship: location_of CCO:B0033633 ! RL13_HUMAN relationship: location_of CCO:B0034271 ! RS25_HUMAN relationship: location_of CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: location_of CCO:B0036028 ! RL21_HUMAN-Phosphothreonine47 relationship: location_of CCO:B0039642 ! RRBP1_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0040516 ! RS14_HUMAN relationship: location_of CCO:B0043446 ! RM10_HUMAN relationship: location_of CCO:B0043592 ! RL23_HUMAN relationship: location_of CCO:B0043825 ! RS15A_HUMAN relationship: location_of CCO:B0053731 ! A2IDC6_HUMAN relationship: location_of CCO:B0053732 ! A2IDC7_HUMAN relationship: location_of CCO:B0055194 ! APEX1_HUMAN relationship: location_of CCO:B0055464 ! RT29_HUMAN relationship: location_of CCO:B0055501 ! RM12_HUMAN relationship: location_of CCO:B0055717 ! RL6_HUMAN relationship: location_of CCO:B0055871 ! RM28_HUMAN relationship: location_of CCO:B0056321 ! Q4TT37_HUMAN relationship: location_of CCO:B0056322 ! Q4TT38_HUMAN relationship: location_of CCO:B0062885 ! RL9_HUMAN relationship: location_of CCO:B0062909 ! RLP24_HUMAN relationship: location_of CCO:B0062930 ! RT18B_HUMAN relationship: location_of CCO:B0063048 ! RL35A_HUMAN relationship: location_of CCO:B0063050 ! RLA0L_HUMAN relationship: location_of CCO:B0063061 ! RS5_HUMAN relationship: location_of CCO:B0063078 ! RS16_HUMAN relationship: location_of CCO:B0063083 ! RL3_HUMAN relationship: location_of CCO:B0063091 ! RL35_HUMAN relationship: location_of CCO:B0063093 ! RL10_HUMAN relationship: location_of CCO:B0063217 ! M11D1_HUMAN relationship: location_of CCO:B0063353 ! RS26_HUMAN relationship: location_of CCO:B0063356 ! RL27A_HUMAN relationship: location_of CCO:B0063360 ! RL23A_HUMAN relationship: location_of CCO:B0063368 ! RS28_HUMAN relationship: location_of CCO:B0063385 ! RM44_HUMAN relationship: location_of CCO:B0063429 ! TGT_HUMAN relationship: location_of CCO:B0063466 ! RT31_HUMAN relationship: location_of CCO:B0063474 ! RS2_HUMAN relationship: location_of CCO:B0063523 ! RM38_HUMAN relationship: location_of CCO:B0066424 ! GCN1L_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0070063 ! RL14_HUMAN-Phosphoserine139 relationship: location_of CCO:B0070068 ! RL1D1_HUMAN-Phosphothreonine358 relationship: location_of CCO:B0070079 ! RL26_HUMAN-Phosphothreonine139 relationship: location_of CCO:B0070080 ! RL29_HUMAN-N6-methyllysine5 relationship: location_of CCO:B0070084 ! RL31_HUMAN-Phosphotyrosine108 relationship: location_of CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 relationship: location_of CCO:B0070200 ! RS11_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 relationship: location_of CCO:B0070222 ! RS8_HUMAN-Phosphothreonine130 relationship: location_of CCO:B0070251 ! RT09_HUMAN-Phosphotyrosine262 relationship: location_of CCO:B0070388 ! SF01_HUMAN-Phosphoserine20 [Term] id: CCO:C0000410 name: polysome namespace: cellular_component def: "Several ribosomes bound to one mRNA." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir synonym: "polyribosome" EXACT [] xref: GO:0005844 is_a: CCO:C0001019 ! ribonucleoprotein complex relationship: location_of CCO:B0005233 ! PSA1_HUMAN relationship: location_of CCO:B0011905 ! FXR1_HUMAN-Omega-N-methylated arginine445 relationship: location_of CCO:B0043290 ! IF2A_HUMAN-Phosphoserine49 relationship: location_of CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 [Term] id: CCO:C0000412 name: nuclear cap binding complex namespace: cellular_component def: "A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export." [PMID:16043498] comment: Note that this complex can be found in the cytoplasm as well as the nucleus. synonym: "CBC" RELATED [] synonym: "mRNA cap binding complex" NARROW [] synonym: "snRNA cap binding complex" NARROW [] xref: GO:0005846 is_a: CCO:C0001843 ! intracellular part is_a: CCO:C0002194 ! RNA cap binding complex [Term] id: CCO:C0000413 name: mRNA cleavage and polyadenylation specificity factor complex namespace: cellular_component def: "A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal." [PMID:14749727] synonym: "CFII complex" RELATED [] synonym: "cleavage and polyadenylylation specificity factor activity" RELATED [] synonym: "CPF complex" NARROW [] synonym: "CPSF complex" NARROW [] xref: GO:0005847 is_a: CCO:C0000415 ! mRNA cleavage factor complex [Term] id: CCO:C0000414 name: mRNA cleavage stimulating factor complex namespace: cellular_component def: "A protein complex required for mRNA cleavage but not for poly(A) addition." [GOC:mah, PMID:10357856] synonym: "cleavage stimulation factor activity" RELATED [] synonym: "CstF complex" NARROW [] xref: GO:0005848 is_a: CCO:C0000415 ! mRNA cleavage factor complex [Term] id: CCO:C0000415 name: mRNA cleavage factor complex namespace: cellular_component def: "Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules." [GOC:mah, PMID:10357856] subset: goslim_pir xref: GO:0005849 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0065893 ! CPSF6_HUMAN-Phosphothreonine404 [Term] id: CCO:C0000416 name: eukaryotic translation initiation factor 2 complex namespace: cellular_component def: "Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA." [PMID:10216940] synonym: "eIF-2" EXACT [] xref: GO:0005850 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0012302 ! IF2B_HUMAN-Phosphoserine2 relationship: location_of CCO:B0016057 ! I2C1_HUMAN relationship: location_of CCO:B0043290 ! IF2A_HUMAN-Phosphoserine49 relationship: location_of CCO:B0064949 ! EIF2A_HUMAN-Phosphothreonine512 [Term] id: CCO:C0000417 name: eukaryotic translation initiation factor 2B complex namespace: cellular_component def: "A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon." [PMID:9438375] synonym: "eIF-2B" EXACT [] xref: GO:0005851 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0015682 ! EI2BA_HUMAN relationship: location_of CCO:B0041299 ! EI2BG_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0043290 ! IF2A_HUMAN-Phosphoserine49 relationship: location_of CCO:B0055434 ! EI2BB_HUMAN relationship: location_of CCO:B0064937 ! EI2BD_HUMAN-Phosphothreonine86 relationship: location_of CCO:B0064938 ! EI2BE_HUMAN-Phosphoserine525 [Term] id: CCO:C0000418 name: eukaryotic translation initiation factor 3 complex namespace: cellular_component def: "A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex." [PMID:15904532] synonym: "eIF-3" EXACT [] synonym: "eIF3" EXACT [] xref: GO:0005852 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0011362 ! CSN5_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0026277 ! EIF3F_HUMAN relationship: location_of CCO:B0026356 ! EIF3B_HUMAN-Phosphotyrosine525 relationship: location_of CCO:B0026366 ! EIF3D_HUMAN-Phosphotyrosine318 relationship: location_of CCO:B0026369 ! EIF3E_HUMAN-Phosphothreonine439 relationship: location_of CCO:B0026373 ! EIF3I_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0026377 ! EIF3K_HUMAN-Phosphoserine217 relationship: location_of CCO:B0041301 ! EIF3J_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064954 ! EIF3A_HUMAN-Phosphoserine584 relationship: location_of CCO:B0064963 ! EIF3C_HUMAN-Phosphoserine15 relationship: location_of CCO:B0064970 ! EIF3H_HUMAN-Phosphoserine183 [Term] id: CCO:C0000419 name: eukaryotic translation elongation factor 1 complex namespace: cellular_component def: "A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma." [GOC:jl, PMID:10216950, UniProtKB:P24534] xref: GO:0005853 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0011635 ! EF1A1_HUMAN-N6,N6,N6-trimethyllysine36 relationship: location_of CCO:B0011644 ! EF1B_HUMAN-Phosphoserine106 relationship: location_of CCO:B0011648 ! EF1G_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0021069 ! EF1D_HUMAN relationship: location_of CCO:B0021083 ! Q96I38_HUMAN relationship: location_of CCO:B0043260 ! EF1A2_HUMAN-N6,N6,N6-trimethyllysine165 [Term] id: CCO:C0000420 name: nascent polypeptide-associated complex namespace: cellular_component def: "A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome." [PMID:12475173, PMID:7568149] synonym: "NAC" EXACT [] synonym: "NACA" EXACT [] xref: GO:0005854 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0013088 ! NACA_HUMAN-Phosphothreonine161 [Term] id: CCO:C0000421 name: cytoskeleton namespace: cellular_component def: "Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, ISBN:0198547684, PMID:16959967] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0005856 is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: location_of CCO:B0001401 ! GAS2_HUMAN relationship: location_of CCO:B0001443 ! BPAEA_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001731 ! CETN1_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0001985 ! GA2L2_HUMAN relationship: location_of CCO:B0002060 ! NEB2_HUMAN relationship: location_of CCO:B0002100 ! KTNB1_HUMAN relationship: location_of CCO:B0002153 ! CYLD_HUMAN relationship: location_of CCO:B0002155 ! ANLN_HUMAN relationship: location_of CCO:B0002156 ! BIN3_HUMAN relationship: location_of CCO:B0002162 ! RASF1_HUMAN relationship: location_of CCO:B0005196 ! Q8N374_HUMAN relationship: location_of CCO:B0005224 ! PDLI7_HUMAN relationship: location_of CCO:B0005253 ! TCPG_HUMAN relationship: location_of CCO:B0005367 ! ARP6_HUMAN relationship: location_of CCO:B0005426 ! CENPJ_HUMAN relationship: location_of CCO:B0005591 ! DISC1_HUMAN relationship: location_of CCO:B0005642 ! ACTN2_HUMAN relationship: location_of CCO:B0005669 ! ELMO1_HUMAN relationship: location_of CCO:B0005672 ! TRADD_HUMAN relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0005810 ! ACTA_HUMAN relationship: location_of CCO:B0005837 ! PAXI_HUMAN relationship: location_of CCO:B0005942 ! WASL_HUMAN relationship: location_of CCO:B0005948 ! ACTN1_HUMAN relationship: location_of CCO:B0005969 ! TRIM1_HUMAN relationship: location_of CCO:B0006028 ! DYH9_HUMAN relationship: location_of CCO:B0006125 ! CAPZB_HUMAN relationship: location_of CCO:B0006153 ! HAP1_HUMAN relationship: location_of CCO:B0006155 ! PROF2_HUMAN relationship: location_of CCO:B0006172 ! ARPC3_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010410 ! ABL1_HUMAN-Phosphoserine809 relationship: location_of CCO:B0010419 ! ABL2_HUMAN-Phosphothreonine440 relationship: location_of CCO:B0010440 ! ACTB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010486 ! AKAP9_HUMAN-Phosphoserine3869 relationship: location_of CCO:B0010604 ! ARP8_HUMAN-Phosphoserine132 relationship: location_of CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: location_of CCO:B0011227 ! CK5P2_HUMAN-Phosphotyrosine461 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0011452 ! DCTN1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: location_of CCO:B0011824 ! FAK1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011839 ! FAK2_HUMAN-Phosphotyrosine881 relationship: location_of CCO:B0011886 ! FNBP1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0011899 ! FRMD6_HUMAN-Phosphoserine525 relationship: location_of CCO:B0012253 ! HOOK1_HUMAN-Phosphoserine235 relationship: location_of CCO:B0012280 ! HSPB1_HUMAN-Phosphoserine26 relationship: location_of CCO:B0012433 ! JAK2_HUMAN-Phosphotyrosine1007 relationship: location_of CCO:B0012434 ! JAK3_HUMAN-Phosphothreonine8 relationship: location_of CCO:B0012475 ! K2C1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0012747 ! MACF1_HUMAN-Phosphoserine1860 relationship: location_of CCO:B0012761 ! MAP9_HUMAN-Phosphoserine132 relationship: location_of CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: location_of CCO:B0013138 ! NDEL1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0013288 ! NUDC_HUMAN-Phosphoserine274 relationship: location_of CCO:B0013463 ! PDLI1_HUMAN-Phosphotyrosine321 relationship: location_of CCO:B0013613 ! PROF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013872 ! RIN1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0014198 ! SPTB2_HUMAN-Phosphothreonine2195 relationship: location_of CCO:B0014317 ! TBB5_HUMAN-Phosphotyrosine36 relationship: location_of CCO:B0014558 ! TYB4_HUMAN-Phosphothreonine23 relationship: location_of CCO:B0014624 ! VIME_HUMAN-Phosphoserine10 relationship: location_of CCO:B0015018 ! PPIP1_HUMAN relationship: location_of CCO:B0015638 ! ACTC_HUMAN relationship: location_of CCO:B0015644 ! ACTH_HUMAN relationship: location_of CCO:B0020591 ! RHOA_HUMAN relationship: location_of CCO:B0021495 ! Q96BT2_HUMAN relationship: location_of CCO:B0021497 ! Q59GD5_HUMAN relationship: location_of CCO:B0022139 ! DYN1_HUMAN relationship: location_of CCO:B0024096 ! Q9BXV5_HUMAN relationship: location_of CCO:B0024099 ! ARPC2_HUMAN relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0026268 ! CACO2_HUMAN relationship: location_of CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: location_of CCO:B0028186 ! ARP2_HUMAN relationship: location_of CCO:B0028914 ! AB1IP_HUMAN relationship: location_of CCO:B0030278 ! RND1_HUMAN relationship: location_of CCO:B0031065 ! FBLI1_HUMAN relationship: location_of CCO:B0031341 ! MTSS1_HUMAN-Phosphotyrosine526 relationship: location_of CCO:B0031540 ! APC2_HUMAN relationship: location_of CCO:B0031598 ! ARC1A_HUMAN relationship: location_of CCO:B0031823 ! MYO3B_HUMAN relationship: location_of CCO:B0032848 ! GDIR1_HUMAN-N6-acetyllysine141 relationship: location_of CCO:B0033320 ! COF1_HUMAN relationship: location_of CCO:B0034503 ! ACTG_HUMAN-N-acetylglutamate2 relationship: location_of CCO:B0034567 ! ARP3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0034592 ! BPA1_HUMAN-Phosphothreonine224 relationship: location_of CCO:B0034678 ! COF2_HUMAN-Phosphoserine3 relationship: location_of CCO:B0034681 ! COR1B_HUMAN-Phosphoserine2 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0035696 ! ST38L_HUMAN-Phosphoserine282 relationship: location_of CCO:B0035773 ! TGFI1_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0038095 ! ABI2_HUMAN relationship: location_of CCO:B0039321 ! ARC1B_HUMAN-Phosphoserine310 relationship: location_of CCO:B0039340 ! CAZA1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039502 ! MARK1_HUMAN-Phosphoserine394 relationship: location_of CCO:B0039518 ! MAST1_HUMAN-Phosphoserine161 relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0041155 ! KI13B_HUMAN-Phosphoserine1644 relationship: location_of CCO:B0041195 ! SIRT2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0041523 ! ANK1_HUMAN relationship: location_of CCO:B0041526 ! ANK3_HUMAN relationship: location_of CCO:B0042506 ! DESP_HUMAN relationship: location_of CCO:B0043195 ! ANK2_HUMAN-Phosphoserine1475 relationship: location_of CCO:B0043273 ! FLNA_HUMAN-Phosphoserine2284 relationship: location_of CCO:B0043276 ! FLNB_HUMAN-Phosphoserine983 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: location_of CCO:B0049167 ! TMSL2_HUMAN relationship: location_of CCO:B0049174 ! TMSL1_HUMAN relationship: location_of CCO:B0049175 ! TMSL3_HUMAN relationship: location_of CCO:B0049176 ! TYB4Y_HUMAN relationship: location_of CCO:B0049179 ! TMSL6_HUMAN relationship: location_of CCO:B0049611 ! ARP3B_HUMAN relationship: location_of CCO:B0051613 ! VILI_HUMAN relationship: location_of CCO:B0052277 ! ADSV_HUMAN-Phosphotyrosine599 relationship: location_of CCO:B0052303 ! AVIL_HUMAN-Phosphotyrosine758 relationship: location_of CCO:B0052375 ! EPIPL_HUMAN-Phosphoserine2691 relationship: location_of CCO:B0052404 ! GELS_HUMAN-Phosphotyrosine603 relationship: location_of CCO:B0052556 ! MAP2_HUMAN-Phosphothreonine1613 relationship: location_of CCO:B0052646 ! PLEC1_HUMAN-Phosphoserine4382 relationship: location_of CCO:B0052884 ! TYB10_HUMAN-N6-acetyllysine4 relationship: location_of CCO:B0052892 ! WDR1_HUMAN-Phosphotyrosine238 relationship: location_of CCO:B0054026 ! A8MTG1_HUMAN relationship: location_of CCO:B0054133 ! A8MYY5_HUMAN relationship: location_of CCO:B0054134 ! A8MYY8_HUMAN relationship: location_of CCO:B0054238 ! B1ALC0_HUMAN relationship: location_of CCO:B0054330 ! KRIT1_HUMAN relationship: location_of CCO:B0054357 ! BORG1_HUMAN relationship: location_of CCO:B0054441 ! ARPC5_HUMAN relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0054982 ! MLRV_HUMAN relationship: location_of CCO:B0055051 ! EPB42_HUMAN relationship: location_of CCO:B0055127 ! NEBU_HUMAN relationship: location_of CCO:B0055135 ! SCF_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055436 ! HINT1_HUMAN relationship: location_of CCO:B0055486 ! GDIR2_HUMAN relationship: location_of CCO:B0055869 ! FLII_HUMAN relationship: location_of CCO:B0056411 ! Q59GM6_HUMAN relationship: location_of CCO:B0056693 ! Q658W2_HUMAN relationship: location_of CCO:B0056821 ! Q6IPM3_HUMAN relationship: location_of CCO:B0056874 ! BORG3_HUMAN relationship: location_of CCO:B0056924 ! ZNT9_HUMAN relationship: location_of CCO:B0056974 ! DNMBP_HUMAN relationship: location_of CCO:B0057029 ! FGD5_HUMAN relationship: location_of CCO:B0057092 ! RAPH1_HUMAN relationship: location_of CCO:B0057198 ! FGD2_HUMAN relationship: location_of CCO:B0057340 ! WASF4_HUMAN relationship: location_of CCO:B0057392 ! Q8IYN9_HUMAN relationship: location_of CCO:B0057419 ! ABRA_HUMAN relationship: location_of CCO:B0057438 ! RHG24_HUMAN relationship: location_of CCO:B0058102 ! EDA_HUMAN relationship: location_of CCO:B0058282 ! FGD4_HUMAN relationship: location_of CCO:B0058409 ! TYBN_HUMAN relationship: location_of CCO:B0058471 ! ARP5L_HUMAN relationship: location_of CCO:B0058538 ! Q9BWW0_HUMAN relationship: location_of CCO:B0058539 ! Q9BWW1_HUMAN relationship: location_of CCO:B0058540 ! Q9BWW2_HUMAN relationship: location_of CCO:B0058583 ! TRI54_HUMAN relationship: location_of CCO:B0058623 ! ARP11_HUMAN relationship: location_of CCO:B0058684 ! TARA_HUMAN relationship: location_of CCO:B0058784 ! RHOF_HUMAN relationship: location_of CCO:B0058894 ! SPTN5_HUMAN relationship: location_of CCO:B0058903 ! C42S2_HUMAN relationship: location_of CCO:B0058904 ! C42S1_HUMAN relationship: location_of CCO:B0059012 ! TMOD2_HUMAN relationship: location_of CCO:B0059177 ! DBNL_HUMAN relationship: location_of CCO:B0059298 ! INVS_HUMAN relationship: location_of CCO:B0062805 ! APBP2_HUMAN relationship: location_of CCO:B0062809 ! HOOK2_HUMAN relationship: location_of CCO:B0062881 ! TPGS2_HUMAN relationship: location_of CCO:B0062914 ! Q96HL7_HUMAN relationship: location_of CCO:B0062931 ! FUZZY_HUMAN relationship: location_of CCO:B0062975 ! WASP_HUMAN relationship: location_of CCO:B0063005 ! GAN_HUMAN relationship: location_of CCO:B0063008 ! WIPF1_HUMAN relationship: location_of CCO:B0063042 ! PTN13_HUMAN relationship: location_of CCO:B0063112 ! UXT_HUMAN relationship: location_of CCO:B0063280 ! MYOTI_HUMAN relationship: location_of CCO:B0063349 ! PTN4_HUMAN relationship: location_of CCO:B0063364 ! ARPC4_HUMAN relationship: location_of CCO:B0063370 ! SRC8_HUMAN relationship: location_of CCO:B0063410 ! MYO15_HUMAN relationship: location_of CCO:B0063496 ! ACTY_HUMAN relationship: location_of CCO:B0063952 ! BORG2_HUMAN-Phosphoserine89 relationship: location_of CCO:B0063956 ! BORG4_HUMAN-Phosphoserine138 relationship: location_of CCO:B0063964 ! BORG5_HUMAN-Phosphoserine121 relationship: location_of CCO:B0064039 ! CABYR_HUMAN-Phosphoserine362 relationship: location_of CCO:B0064079 ! CASP8_HUMAN-Phosphotyrosine334 relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0064358 ! CIP4_HUMAN-Phosphoserine335 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0064587 ! CTNL1_HUMAN-Phosphoserine538 relationship: location_of CCO:B0064669 ! DCX_HUMAN-Phosphoserine196 relationship: location_of CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: location_of CCO:B0065175 ! EVL_HUMAN-Phosphoserine306 relationship: location_of CCO:B0065282 ! ABLM1_HUMAN-Phosphoserine216 relationship: location_of CCO:B0065410 ! ADCYA_HUMAN-Phosphothreonine809 relationship: location_of CCO:B0065511 ! AKA12_HUMAN-Phosphoserine565 relationship: location_of CCO:B0065551 ! AKAP4_HUMAN-Phosphoserine492 relationship: location_of CCO:B0065958 ! DOCK2_HUMAN-Phosphoserine1706 relationship: location_of CCO:B0065965 ! E41L3_HUMAN-Phosphothreonine703 relationship: location_of CCO:B0066128 ! FARP1_HUMAN-Phosphoserine896 relationship: location_of CCO:B0066133 ! FARP2_HUMAN-Phosphoserine881 relationship: location_of CCO:B0066163 ! FERM2_HUMAN-Phosphoserine181 relationship: location_of CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: location_of CCO:B0066179 ! FGD3_HUMAN-Phosphoserine128 relationship: location_of CCO:B0066183 ! FGD6_HUMAN-Phosphoserine721 relationship: location_of CCO:B0066213 ! FLNC_HUMAN-Phosphotyrosine2683 relationship: location_of CCO:B0066344 ! GA2L1_HUMAN-Phosphothreonine391 relationship: location_of CCO:B0067002 ! ICLN_HUMAN-Phosphoserine102 relationship: location_of CCO:B0067238 ! K1688_HUMAN-Phosphoserine406 relationship: location_of CCO:B0067251 ! KALRN_HUMAN-Phosphoserine1750 relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: location_of CCO:B0067575 ! LASP1_HUMAN-Phosphoserine146 relationship: location_of CCO:B0067657 ! LIMA1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0067781 ! LRRF1_HUMAN-Phosphoserine581 relationship: location_of CCO:B0067835 ! MACF4_HUMAN-Phosphoserine2362 relationship: location_of CCO:B0067998 ! MAST2_HUMAN-Phosphoserine74 relationship: location_of CCO:B0068055 ! MCF2_HUMAN-Phosphoserine742 relationship: location_of CCO:B0068173 ! MICA1_HUMAN-Phosphoserine876 relationship: location_of CCO:B0068275 ! MRCKB_HUMAN-Phosphoserine221 relationship: location_of CCO:B0068346 ! MY18A_HUMAN-Phosphoserine2020 relationship: location_of CCO:B0068390 ! MYO10_HUMAN-Phosphoserine968 relationship: location_of CCO:B0068587 ! NEXN_HUMAN-Phosphoserine365 relationship: location_of CCO:B0068681 ! NFM_HUMAN-Phosphoserine654 relationship: location_of CCO:B0068796 ! NOSTN_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0069148 ! PBIP1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0069178 ! PDE4D_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0069412 ! PLEK2_HUMAN-Phosphotyrosine333 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 relationship: location_of CCO:B0070697 ! SNTA1_HUMAN-Phosphoserine189 relationship: location_of CCO:B0070704 ! SNTB1_HUMAN-Phosphoserine389 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: location_of CCO:B0070821 ! SPTA2_HUMAN-Phosphoserine1217 relationship: location_of CCO:B0070827 ! SPTB1_HUMAN-Phosphoserine2117 relationship: location_of CCO:B0070838 ! SPTN2_HUMAN-Phosphothreonine2354 relationship: location_of CCO:B0070840 ! SPTN4_HUMAN-Phosphothreonine2112 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0071208 ! TBB2C_HUMAN-Phosphoserine322 relationship: location_of CCO:B0071434 ! TMOD3_HUMAN-Phosphoserine25 relationship: location_of CCO:B0071477 ! TPM1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0071480 ! TPM2_HUMAN-Phosphoserine283 relationship: location_of CCO:B0071481 ! TPM3_HUMAN-Phosphotyrosine162 relationship: location_of CCO:B0071661 ! UACA_HUMAN-Phosphotyrosine723 relationship: location_of CCO:B0071778 ! VASP_HUMAN-Phosphotyrosine39 relationship: location_of CCO:B0071803 ! VINEX_HUMAN-Phosphothreonine529 relationship: location_of CCO:B0071823 ! WASF2_HUMAN-Phosphoserine482 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000422 name: axonemal dynein complex namespace: cellular_component def: "A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which in converted to a bending motion. May contain two or three dynein heavy chains as well as several light chains." [ISBN:0815316194] synonym: "axonemal dynein heavy chain" NARROW [] synonym: "axonemal dynein intermediate chain" NARROW [] synonym: "axonemal dynein intermediate light chain" NARROW [] synonym: "axonemal dynein light chain" NARROW [] xref: GO:0005858 is_a: CCO:C0000995 ! dynein complex is_a: CCO:C0001866 ! axoneme part relationship: location_of CCO:B0006028 ! DYH9_HUMAN [Term] id: CCO:C0000423 name: muscle myosin complex namespace: cellular_component def: "A filament of myosin found in a muscle cell of any type." [GOC:mah] xref: GO:0005859 is_a: CCO:C0000789 ! myosin II complex is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0068380 ! MYL9_HUMAN-Phosphoserine29 [Term] id: CCO:C0000424 name: troponin complex namespace: cellular_component def: "A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction." [ISBN:0815316194] xref: GO:0005861 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0043494 ! TNNT1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0055412 ! TNNI2_HUMAN relationship: location_of CCO:B0071441 ! TNNC1_HUMAN-N-acetylmethionine1 relationship: part_of CCO:C0000427 ! striated muscle thin filament [Term] id: CCO:C0000425 name: muscle thin filament tropomyosin namespace: cellular_component def: "A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments." [ISBN:0815316194] xref: GO:0005862 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0071477 ! TPM1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0071480 ! TPM2_HUMAN-Phosphoserine283 relationship: location_of CCO:B0071481 ! TPM3_HUMAN-Phosphotyrosine162 relationship: part_of CCO:C0000427 ! striated muscle thin filament [Term] id: CCO:C0000426 name: striated muscle thick filament namespace: cellular_component def: "Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils." [GOC:mtg_muscle, ISBN:0815316194] xref: GO:0005863 is_a: CCO:C0000423 ! muscle myosin complex is_a: CCO:C0001490 ! myosin filament relationship: location_of CCO:B0035225 ! MYH1_HUMAN-Phosphothreonine1933 relationship: location_of CCO:B0056023 ! MYPC3_HUMAN relationship: part_of CCO:C0000933 ! sarcomere [Term] id: CCO:C0000427 name: striated muscle thin filament namespace: cellular_component def: "Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils." [ISBN:0815316194] xref: GO:0005865 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001868 ! contractile fiber part relationship: part_of CCO:C0000753 ! actin cytoskeleton relationship: part_of CCO:C0000933 ! sarcomere [Term] id: CCO:C0000428 name: cytoplasmic dynein complex namespace: cellular_component def: "Any dynein complex that catalyzes movement along a cytoplasmic microtubule; cytoplasmic dynein complexes participates in many transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes,and may include light chains and light intermediate chains." [GOC:mah, PMID:12600311] synonym: "cytoplasmic dynein heavy chain" NARROW [] synonym: "cytoplasmic dynein intermediate chain" NARROW [] synonym: "cytoplasmic dynein intermediate light chain" NARROW [] synonym: "cytoplasmic dynein light chain" NARROW [] xref: GO:0005868 is_a: CCO:C0000995 ! dynein complex relationship: location_of CCO:B0001780 ! DYHC1_HUMAN relationship: location_of CCO:B0005562 ! DLRB1_HUMAN relationship: location_of CCO:B0006226 ! DYL1_HUMAN relationship: location_of CCO:B0011441 ! DC1I1_HUMAN-Phosphoserine635 relationship: location_of CCO:B0063409 ! DC1L2_HUMAN [Term] id: CCO:C0000429 name: dynactin complex namespace: cellular_component def: "A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005869 is_a: CCO:C0000435 ! microtubule associated complex relationship: location_of CCO:B0001440 ! DCTN3_HUMAN relationship: location_of CCO:B0063496 ! ACTY_HUMAN relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0000430 name: actin capping protein of dynactin complex namespace: cellular_component def: "A heterodimer consisting of alpha and a beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex." [GOC:jl, UniProtKB:P14315] xref: GO:0005870 is_a: CCO:C0000542 ! F-actin capping protein complex relationship: part_of CCO:C0000429 ! dynactin complex [Term] id: CCO:C0000431 name: kinesin complex namespace: cellular_component def: "Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work." [GOC:mah, http://www.proweb.org/kinesin//KinesinMotility.html, http://www.proweb.org/kinesin//KinesinStructure.html] xref: GO:0005871 is_a: CCO:C0000435 ! microtubule associated complex relationship: location_of CCO:B0002208 ! KIF25_HUMAN relationship: location_of CCO:B0005599 ! KINH_HUMAN relationship: location_of CCO:B0006166 ! KIF5A_HUMAN relationship: location_of CCO:B0012584 ! KIF11_HUMAN-Phosphothreonine926 relationship: location_of CCO:B0012594 ! KIF23_HUMAN-Phosphoserine682 relationship: location_of CCO:B0012608 ! KIF3C_HUMAN-Phosphothreonine585 relationship: location_of CCO:B0058104 ! KIFA3_HUMAN relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 [Term] id: CCO:C0000432 name: minus-end kinesin complex namespace: cellular_component def: "Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule." [GOC:mah] xref: GO:0005872 is_a: CCO:C0000431 ! kinesin complex [Term] id: CCO:C0000433 name: plus-end kinesin complex namespace: cellular_component def: "Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule." [GOC:mah] xref: GO:0005873 is_a: CCO:C0000431 ! kinesin complex relationship: location_of CCO:B0002165 ! KIF15_HUMAN [Term] id: CCO:C0000434 name: microtubule namespace: cellular_component def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] xref: GO:0005874 is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0001427 ! KTNA1_HUMAN relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001754 ! TBB3_HUMAN relationship: location_of CCO:B0001769 ! TBB2A_HUMAN relationship: location_of CCO:B0001780 ! DYHC1_HUMAN relationship: location_of CCO:B0001792 ! KIF22_HUMAN relationship: location_of CCO:B0001963 ! KIF2B_HUMAN relationship: location_of CCO:B0002008 ! RASF5_HUMAN relationship: location_of CCO:B0002034 ! CCDC5_HUMAN relationship: location_of CCO:B0002056 ! MPPH1_HUMAN relationship: location_of CCO:B0002100 ! KTNB1_HUMAN relationship: location_of CCO:B0002162 ! RASF1_HUMAN relationship: location_of CCO:B0002165 ! KIF15_HUMAN relationship: location_of CCO:B0002180 ! GTSE1_HUMAN relationship: location_of CCO:B0002208 ! KIF25_HUMAN relationship: location_of CCO:B0002211 ! TBE_HUMAN relationship: location_of CCO:B0002238 ! MARE3_HUMAN relationship: location_of CCO:B0005281 ! M1IP1_HUMAN relationship: location_of CCO:B0005426 ! CENPJ_HUMAN relationship: location_of CCO:B0005562 ! DLRB1_HUMAN relationship: location_of CCO:B0005591 ! DISC1_HUMAN relationship: location_of CCO:B0005599 ! KINH_HUMAN relationship: location_of CCO:B0005966 ! KIF17_HUMAN relationship: location_of CCO:B0005969 ! TRIM1_HUMAN relationship: location_of CCO:B0006028 ! DYH9_HUMAN relationship: location_of CCO:B0006166 ! KIF5A_HUMAN relationship: location_of CCO:B0006167 ! TBB4_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006226 ! DYL1_HUMAN relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: location_of CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: location_of CCO:B0011239 ! CKAP2_HUMAN-Phosphoserine602 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0011441 ! DC1I1_HUMAN-Phosphoserine635 relationship: location_of CCO:B0011452 ! DCTN1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: location_of CCO:B0012168 ! HDAC6_HUMAN-Phosphoserine22 relationship: location_of CCO:B0012253 ! HOOK1_HUMAN-Phosphoserine235 relationship: location_of CCO:B0012399 ! INCE_HUMAN-Phosphoserine296 relationship: location_of CCO:B0012584 ! KIF11_HUMAN-Phosphothreonine926 relationship: location_of CCO:B0012594 ! KIF23_HUMAN-Phosphoserine682 relationship: location_of CCO:B0012607 ! KIF3A_HUMAN-Phosphoserine690 relationship: location_of CCO:B0012608 ! KIF3C_HUMAN-Phosphothreonine585 relationship: location_of CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0012723 ! M3K11_HUMAN-Phosphoserine724 relationship: location_of CCO:B0012761 ! MAP9_HUMAN-Phosphoserine132 relationship: location_of CCO:B0012763 ! MARE1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: location_of CCO:B0013138 ! NDEL1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0013288 ! NUDC_HUMAN-Phosphoserine274 relationship: location_of CCO:B0013610 ! PRC1_HUMAN-Phosphothreonine481 relationship: location_of CCO:B0013810 ! RCC2_HUMAN-Phosphothreonine20 relationship: location_of CCO:B0014015 ! SEPT9_HUMAN-Phosphoserine89 relationship: location_of CCO:B0014164 ! SPAG5_HUMAN-Phosphoserine249 relationship: location_of CCO:B0014264 ! STMN1_HUMAN-Phosphoserine63 relationship: location_of CCO:B0014308 ! TBA1A_HUMAN-Phosphoserine6 relationship: location_of CCO:B0014311 ! TBA1B_HUMAN-Phosphotyrosine272 relationship: location_of CCO:B0014317 ! TBB5_HUMAN-Phosphotyrosine36 relationship: location_of CCO:B0018956 ! RASF3_HUMAN relationship: location_of CCO:B0019877 ! Q7KZS6_HUMAN relationship: location_of CCO:B0022139 ! DYN1_HUMAN relationship: location_of CCO:B0024576 ! TBA3C_HUMAN relationship: location_of CCO:B0024578 ! TBA8_HUMAN relationship: location_of CCO:B0031378 ! TBB2B_HUMAN-Phosphotyrosine36 relationship: location_of CCO:B0031540 ! APC2_HUMAN relationship: location_of CCO:B0039483 ! KI18A_HUMAN-Phosphoserine357 relationship: location_of CCO:B0039949 ! FSD1_HUMAN relationship: location_of CCO:B0041155 ! KI13B_HUMAN-Phosphoserine1644 relationship: location_of CCO:B0041195 ! SIRT2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0041206 ! TBA4A_HUMAN-Phosphotyrosine440 relationship: location_of CCO:B0051353 ! GBRL1_HUMAN relationship: location_of CCO:B0052556 ! MAP2_HUMAN-Phosphothreonine1613 relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0054905 ! DPOLB_HUMAN relationship: location_of CCO:B0055823 ! DYH14_HUMAN relationship: location_of CCO:B0056135 ! Q16296_HUMAN relationship: location_of CCO:B0056188 ! Q17S04_HUMAN relationship: location_of CCO:B0057294 ! CEP57_HUMAN relationship: location_of CCO:B0057329 ! Q8IUX2_HUMAN relationship: location_of CCO:B0057579 ! Q8NDS5_HUMAN relationship: location_of CCO:B0057897 ! Q8TB56_HUMAN relationship: location_of CCO:B0058028 ! DYH12_HUMAN relationship: location_of CCO:B0058137 ! TRI63_HUMAN relationship: location_of CCO:B0058583 ! TRI54_HUMAN relationship: location_of CCO:B0058584 ! TRI55_HUMAN relationship: location_of CCO:B0059298 ! INVS_HUMAN relationship: location_of CCO:B0062805 ! APBP2_HUMAN relationship: location_of CCO:B0062809 ! HOOK2_HUMAN relationship: location_of CCO:B0062812 ! DYL2_HUMAN relationship: location_of CCO:B0062881 ! TPGS2_HUMAN relationship: location_of CCO:B0062970 ! NIN_HUMAN relationship: location_of CCO:B0063053 ! ARHG2_HUMAN relationship: location_of CCO:B0063064 ! TBA4B_HUMAN relationship: location_of CCO:B0063110 ! Q8N532_HUMAN relationship: location_of CCO:B0063409 ! DC1L2_HUMAN relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: location_of CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0065055 ! EMAL4_HUMAN-Phosphoserine934 relationship: location_of CCO:B0067359 ! KIF22_HUMAN-Phosphoserine412 relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: location_of CCO:B0067928 ! MAP1B_HUMAN-Phosphotyrosine1974 relationship: location_of CCO:B0067973 ! MAP4_HUMAN-Phosphothreonine828 relationship: location_of CCO:B0067988 ! MARE2_HUMAN-Phosphoserine208 relationship: location_of CCO:B0068948 ! NUSAP_HUMAN-Phosphothreonine349 relationship: location_of CCO:B0069148 ! PBIP1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0069906 ! RGAP1_HUMAN-Phosphoserine600 relationship: location_of CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0071208 ! TBB2C_HUMAN-Phosphoserine322 relationship: part_of CCO:C0000754 ! microtubule cytoskeleton [Term] id: CCO:C0000435 name: microtubule associated complex namespace: cellular_component def: "Any multimeric complex connected to a microtubule." [GOC:jl] xref: GO:0005875 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001792 ! KIF22_HUMAN relationship: location_of CCO:B0001963 ! KIF2B_HUMAN relationship: location_of CCO:B0002056 ! MPPH1_HUMAN relationship: location_of CCO:B0002165 ! KIF15_HUMAN relationship: location_of CCO:B0002208 ! KIF25_HUMAN relationship: location_of CCO:B0002254 ! RBGP1_HUMAN relationship: location_of CCO:B0005483 ! STAU1_HUMAN relationship: location_of CCO:B0005599 ! KINH_HUMAN relationship: location_of CCO:B0005837 ! PAXI_HUMAN relationship: location_of CCO:B0005966 ! KIF17_HUMAN relationship: location_of CCO:B0005969 ! TRIM1_HUMAN relationship: location_of CCO:B0006166 ! KIF5A_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006226 ! DYL1_HUMAN relationship: location_of CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: location_of CCO:B0012584 ! KIF11_HUMAN-Phosphothreonine926 relationship: location_of CCO:B0012594 ! KIF23_HUMAN-Phosphoserine682 relationship: location_of CCO:B0012607 ! KIF3A_HUMAN-Phosphoserine690 relationship: location_of CCO:B0012608 ! KIF3C_HUMAN-Phosphothreonine585 relationship: location_of CCO:B0012610 ! KIFC1_HUMAN-Phosphoserine351 relationship: location_of CCO:B0039483 ! KI18A_HUMAN-Phosphoserine357 relationship: location_of CCO:B0041155 ! KI13B_HUMAN-Phosphoserine1644 relationship: location_of CCO:B0052556 ! MAP2_HUMAN-Phosphothreonine1613 relationship: location_of CCO:B0056135 ! Q16296_HUMAN relationship: location_of CCO:B0062805 ! APBP2_HUMAN relationship: location_of CCO:B0062812 ! DYL2_HUMAN relationship: location_of CCO:B0063004 ! RANB9_HUMAN relationship: location_of CCO:B0063448 ! STAR9_HUMAN relationship: location_of CCO:B0064669 ! DCX_HUMAN-Phosphoserine196 relationship: location_of CCO:B0067359 ! KIF22_HUMAN-Phosphoserine412 relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: location_of CCO:B0067928 ! MAP1B_HUMAN-Phosphotyrosine1974 relationship: location_of CCO:B0067973 ! MAP4_HUMAN-Phosphothreonine828 relationship: location_of CCO:B0069197 ! PEA15_HUMAN-Phosphothreonine6 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: part_of CCO:C0000754 ! microtubule cytoskeleton [Term] id: CCO:C0000436 name: spindle microtubule namespace: cellular_component def: "Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole." [ISBN:0815316194] xref: GO:0005876 is_a: CCO:C0000434 ! microtubule relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0011054 ! CDC16_HUMAN-Phosphoserine560 relationship: location_of CCO:B0011069 ! CDC27_HUMAN-Phosphothreonine209 relationship: location_of CCO:B0011078 ! CDC2_HUMAN-Phosphothreonine14 relationship: location_of CCO:B0012584 ! KIF11_HUMAN-Phosphothreonine926 relationship: location_of CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0013610 ! PRC1_HUMAN-Phosphothreonine481 relationship: location_of CCO:B0014164 ! SPAG5_HUMAN-Phosphoserine249 relationship: location_of CCO:B0054905 ! DPOLB_HUMAN relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: part_of CCO:C0000388 ! spindle [Term] id: CCO:C0000437 name: axonemal microtubule namespace: cellular_component def: "A microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [ISBN:0815316194] xref: GO:0005879 is_a: CCO:C0000434 ! microtubule is_a: CCO:C0001866 ! axoneme part [Term] id: CCO:C0000438 name: nuclear microtubule namespace: cellular_component def: "Any microtubule in the nucleus of a cell." [GOC:mah] xref: GO:0005880 is_a: CCO:C0000434 ! microtubule is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000439 name: cytoplasmic microtubule namespace: cellular_component def: "Any microtubule in the cytoplasm of a cell." [GOC:mah] synonym: "non-spindle-associated astral microtubule" NARROW [] xref: GO:0005881 is_a: CCO:C0000434 ! microtubule relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0002180 ! GTSE1_HUMAN relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0011252 ! CLAP2_HUMAN-Phosphoserine326 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 [Term] id: CCO:C0000440 name: intermediate filament namespace: cellular_component def: "A distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: keratin filaments of mammalian epithelial cells; desmin filaments found in cells of muscles of all types; vimentin filaments found in mesenchymal cells; neurofilaments of neurons; and glial filaments found in all types of glial cells." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "intermediate filament associated protein" RELATED [] synonym: "type I intermediate filament associated protein" RELATED [] synonym: "type II intermediate filament associated protein" RELATED [] xref: GO:0005882 is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0005207 ! K1C15_HUMAN relationship: location_of CCO:B0005293 ! KR412_HUMAN relationship: location_of CCO:B0005811 ! K2C5_HUMAN relationship: location_of CCO:B0005817 ! K1C14_HUMAN relationship: location_of CCO:B0005922 ! K1C9_HUMAN relationship: location_of CCO:B0012459 ! K1C17_HUMAN-Phosphoserine319 relationship: location_of CCO:B0012464 ! K1C18_HUMAN-Phosphoserine15 relationship: location_of CCO:B0012475 ! K2C1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0012480 ! K2C6A_HUMAN-Phosphoserine60 relationship: location_of CCO:B0012485 ! K2C7_HUMAN-Phosphotyrosine375 relationship: location_of CCO:B0012493 ! K2C8_HUMAN-Phosphoserine27 relationship: location_of CCO:B0013172 ! NFL_HUMAN-Phosphoserine472 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0014624 ! VIME_HUMAN-Phosphoserine10 relationship: location_of CCO:B0023704 ! K1C16_HUMAN relationship: location_of CCO:B0023715 ! K1C10_HUMAN relationship: location_of CCO:B0032342 ! K2C74_HUMAN relationship: location_of CCO:B0034943 ! K22E_HUMAN-Phosphoserine62 relationship: location_of CCO:B0034948 ! K2C4_HUMAN-Phosphoserine51 relationship: location_of CCO:B0039927 ! K1C20_HUMAN-Phosphoserine13 relationship: location_of CCO:B0055024 ! DRD2_HUMAN relationship: location_of CCO:B0055947 ! PKP1_HUMAN relationship: location_of CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0066445 ! GFAP_HUMAN-Phosphothreonine110 relationship: location_of CCO:B0067706 ! LMNA_HUMAN-Phosphothreonine416 relationship: location_of CCO:B0067727 ! LMNB1_HUMAN-Phosphothreonine575 relationship: location_of CCO:B0068173 ! MICA1_HUMAN-Phosphoserine876 relationship: location_of CCO:B0068681 ! NFM_HUMAN-Phosphoserine654 relationship: location_of CCO:B0070801 ! SPN90_HUMAN-Phosphothreonine181 relationship: part_of CCO:C0001888 ! intermediate filament cytoskeleton [Term] id: CCO:C0000441 name: neurofilament namespace: cellular_component def: "A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0716731363, ISBN:0815316194] synonym: "type IV intermediate filament" EXACT [] xref: GO:0005883 is_a: CCO:C0000440 ! intermediate filament relationship: location_of CCO:B0013172 ! NFL_HUMAN-Phosphoserine472 relationship: location_of CCO:B0063005 ! GAN_HUMAN relationship: location_of CCO:B0068681 ! NFM_HUMAN-Phosphoserine654 relationship: part_of CCO:C0002030 ! neurofilament cytoskeleton [Term] id: CCO:C0000442 name: actin filament namespace: cellular_component def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:10666339] synonym: "microfilament" BROAD [] xref: GO:0005884 is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0001401 ! GAS2_HUMAN relationship: location_of CCO:B0005642 ! ACTN2_HUMAN relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0015638 ! ACTC_HUMAN relationship: location_of CCO:B0020080 ! ACTN3_HUMAN relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0034880 ! IQGA1_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0063398 ! VPS11_HUMAN relationship: location_of CCO:B0065618 ! AMOT_HUMAN-Phosphoserine312 relationship: location_of CCO:B0069419 ! PLSL_HUMAN-Phosphotyrosine28 relationship: location_of CCO:B0069944 ! RHG06_HUMAN-Phosphoserine754 relationship: location_of CCO:B0070469 ! SH2B2_HUMAN-Phosphotyrosine629 relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0000443 name: Arp2/3 protein complex namespace: cellular_component def: "A stable complex of seven subunits, two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5). Functions in the nucleation of actin filaments." [GOC:jl, PMID:12479800] xref: GO:0005885 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0006172 ! ARPC3_HUMAN relationship: location_of CCO:B0024099 ! ARPC2_HUMAN relationship: location_of CCO:B0028186 ! ARP2_HUMAN relationship: location_of CCO:B0034567 ! ARP3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039321 ! ARC1B_HUMAN-Phosphoserine310 relationship: location_of CCO:B0054441 ! ARPC5_HUMAN relationship: location_of CCO:B0063364 ! ARPC4_HUMAN relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0000444 name: plasma membrane namespace: cellular_component def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] subset: goslim_candida subset: goslim_generic subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cytoplasmic membrane" EXACT [] synonym: "inner endospore membrane" NARROW [] synonym: "juxtamembrane" BROAD [] synonym: "plasmalemma" EXACT [] xref: GO:0005886 is_a: CCO:C0000766 ! membrane relationship: location_of CCO:B0001406 ! ADCY3_HUMAN relationship: location_of CCO:B0001448 ! TNF15_HUMAN relationship: location_of CCO:B0001453 ! DIRA3_HUMAN relationship: location_of CCO:B0001455 ! RECK_HUMAN relationship: location_of CCO:B0001466 ! RASN_HUMAN relationship: location_of CCO:B0001470 ! EGF_HUMAN relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0001477 ! IL2RA_HUMAN relationship: location_of CCO:B0001490 ! LCK_HUMAN relationship: location_of CCO:B0001517 ! IFM1_HUMAN relationship: location_of CCO:B0001557 ! PAR1_HUMAN relationship: location_of CCO:B0001569 ! SHC1_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0001672 ! GAS1_HUMAN relationship: location_of CCO:B0001692 ! RHOB_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0001719 ! NOTC2_HUMAN relationship: location_of CCO:B0001758 ! ULA1_HUMAN relationship: location_of CCO:B0001767 ! BMPR2_HUMAN relationship: location_of CCO:B0001838 ! PKHO1_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0002023 ! ARHG1_HUMAN relationship: location_of CCO:B0002029 ! TP4A1_HUMAN relationship: location_of CCO:B0002064 ! GML_HUMAN relationship: location_of CCO:B0002079 ! Q99648_HUMAN relationship: location_of CCO:B0002085 ! SEPT5_HUMAN relationship: location_of CCO:B0002110 ! CADM1_HUMAN relationship: location_of CCO:B0002112 ! PAR6G_HUMAN relationship: location_of CCO:B0002113 ! PAR6B_HUMAN relationship: location_of CCO:B0002135 ! PIGU_HUMAN relationship: location_of CCO:B0002150 ! PAR6A_HUMAN relationship: location_of CCO:B0002175 ! NSMA2_HUMAN relationship: location_of CCO:B0002236 ! GP132_HUMAN relationship: location_of CCO:B0002248 ! LZTS1_HUMAN relationship: location_of CCO:B0002265 ! USH1C_HUMAN relationship: location_of CCO:B0005197 ! AP2B1_HUMAN relationship: location_of CCO:B0005237 ! RB22A_HUMAN relationship: location_of CCO:B0005338 ! CDC42_HUMAN relationship: location_of CCO:B0005374 ! APLP2_HUMAN relationship: location_of CCO:B0005393 ! FEZ1_HUMAN relationship: location_of CCO:B0005428 ! CSK21_HUMAN relationship: location_of CCO:B0005447 ! NRP1_HUMAN relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0005450 ! ICAM1_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005479 ! TNR6_HUMAN relationship: location_of CCO:B0005506 ! FSHR_HUMAN relationship: location_of CCO:B0005512 ! AKT1_HUMAN relationship: location_of CCO:B0005534 ! TNR1A_HUMAN relationship: location_of CCO:B0005535 ! TNR1B_HUMAN relationship: location_of CCO:B0005543 ! AVR2A_HUMAN relationship: location_of CCO:B0005546 ! CELR3_HUMAN relationship: location_of CCO:B0005549 ! MEG10_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005618 ! TRBM_HUMAN relationship: location_of CCO:B0005646 ! FGFP1_HUMAN relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0005669 ! ELMO1_HUMAN relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0005692 ! CAC1C_HUMAN relationship: location_of CCO:B0005701 ! HDA11_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0005723 ! MTR1A_HUMAN relationship: location_of CCO:B0005724 ! MTR1B_HUMAN relationship: location_of CCO:B0005740 ! CD4_HUMAN relationship: location_of CCO:B0005760 ! NEP_HUMAN relationship: location_of CCO:B0005779 ! ENOA_HUMAN relationship: location_of CCO:B0005837 ! PAXI_HUMAN relationship: location_of CCO:B0005851 ! DIRA2_HUMAN relationship: location_of CCO:B0005868 ! FGFR1_HUMAN relationship: location_of CCO:B0005870 ! TGFA_HUMAN relationship: location_of CCO:B0005875 ! CD59_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0005974 ! NOTC1_HUMAN relationship: location_of CCO:B0006019 ! LPP3_HUMAN relationship: location_of CCO:B0006022 ! PCDH9_HUMAN relationship: location_of CCO:B0006029 ! PANX3_HUMAN relationship: location_of CCO:B0006081 ! CBPE_HUMAN relationship: location_of CCO:B0006099 ! PCDA4_HUMAN relationship: location_of CCO:B0006141 ! FXYD6_HUMAN relationship: location_of CCO:B0006148 ! HMOX2_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0006179 ! APLP1_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006226 ! DYL1_HUMAN relationship: location_of CCO:B0006229 ! RIT1_HUMAN relationship: location_of CCO:B0006244 ! TDGF1_HUMAN relationship: location_of CCO:B0006259 ! BOC_HUMAN relationship: location_of CCO:B0006269 ! EFNA1_HUMAN relationship: location_of CCO:B0006270 ! ENOG_HUMAN relationship: location_of CCO:B0006285 ! GRIK5_HUMAN relationship: location_of CCO:B0006294 ! PTOV1_HUMAN relationship: location_of CCO:B0006306 ! GP135_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0006334 ! AMRP_HUMAN relationship: location_of CCO:B0010427 ! ACK1_HUMAN-Phosphoserine149 relationship: location_of CCO:B0010433 ! ACL6A_HUMAN-Phosphoserine233 relationship: location_of CCO:B0010459 ! ADAM9_HUMAN-Phosphothreonine761 relationship: location_of CCO:B0010556 ! ANXA2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010814 ! BMR1A_HUMAN-Phosphoserine220 relationship: location_of CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0010912 ! CALM_HUMAN-N6,N6,N6-trimethyllysine116 relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0010952 ! CBL_HUMAN-Phosphoserine900 relationship: location_of CCO:B0011014 ! CD28_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0011050 ! CD45_HUMAN-Phosphoserine1003 relationship: location_of CCO:B0011338 ! CPNS1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011355 ! CSK_HUMAN-Phosphotyrosine304 relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0011392 ! CTND1_HUMAN-Phosphoserine269 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0011527 ! DLG5_HUMAN-Phosphothreonine1011 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0011697 ! EP15_HUMAN-Phosphoserine324 relationship: location_of CCO:B0011824 ! FAK1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011839 ! FAK2_HUMAN-Phosphotyrosine881 relationship: location_of CCO:B0011879 ! FGFR2_HUMAN-Phosphotyrosine657 relationship: location_of CCO:B0011886 ! FNBP1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0011899 ! FRMD6_HUMAN-Phosphoserine525 relationship: location_of CCO:B0011949 ! GNAI1_HUMAN-ADP-ribosylarginine178 relationship: location_of CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: location_of CCO:B0012627 ! KPCA_HUMAN-Phosphoserine657 relationship: location_of CCO:B0012636 ! KPCZ_HUMAN-Phosphothreonine560 relationship: location_of CCO:B0012697 ! LEPR_HUMAN-Phosphotyrosine1141 relationship: location_of CCO:B0013032 ! MTFR1_HUMAN-Phosphoserine33 relationship: location_of CCO:B0013046 ! MTUS1_HUMAN-Phosphoserine1264 relationship: location_of CCO:B0013157 ! NELF_HUMAN-Phosphoserine288 relationship: location_of CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013375 ! PAK1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0013393 ! PARD3_HUMAN-Phosphoserine717 relationship: location_of CCO:B0013478 ! PDPK1_HUMAN-Phosphoserine241 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0013541 ! PKD2_HUMAN-Phosphoserine254 relationship: location_of CCO:B0013563 ! PLCB1_HUMAN-N6-acetyllysine976 relationship: location_of CCO:B0013567 ! PLCG1_HUMAN-Phosphotyrosine1253 relationship: location_of CCO:B0013659 ! RAC1_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0013681 ! RAF1_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013709 ! RAP1A_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0013716 ! RASK_HUMAN-ester186 relationship: location_of CCO:B0013859 ! RHOG_HUMAN-Cysteine methyl ester188 relationship: location_of CCO:B0013872 ! RIN1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0014015 ! SEPT9_HUMAN-Phosphoserine89 relationship: location_of CCO:B0014054 ! SH3G2_HUMAN-Phosphoserine75 relationship: location_of CCO:B0014198 ! SPTB2_HUMAN-Phosphothreonine2195 relationship: location_of CCO:B0014349 ! TGFR2_HUMAN-Phosphoserine548 relationship: location_of CCO:B0014355 ! THRB_HUMAN-4-carboxyglutamate59 relationship: location_of CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0014615 ! VGFR1_HUMAN-Phosphotyrosine1213 relationship: location_of CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0014946 ! EPHAA_HUMAN relationship: location_of CCO:B0014957 ! EPHA8_HUMAN relationship: location_of CCO:B0015065 ! CRTAM_HUMAN relationship: location_of CCO:B0015122 ! GLR_HUMAN relationship: location_of CCO:B0015123 ! GLP1R_HUMAN relationship: location_of CCO:B0015124 ! GIPR_HUMAN relationship: location_of CCO:B0015126 ! Q8NHB4_HUMAN relationship: location_of CCO:B0015134 ! GLP2R_HUMAN relationship: location_of CCO:B0015136 ! SCTR_HUMAN relationship: location_of CCO:B0015164 ! HHIP_HUMAN relationship: location_of CCO:B0015288 ! ARF1_HUMAN relationship: location_of CCO:B0015543 ! SMAP1_HUMAN relationship: location_of CCO:B0015673 ! CHL1_HUMAN relationship: location_of CCO:B0015682 ! EI2BA_HUMAN relationship: location_of CCO:B0015779 ! PILRA_HUMAN relationship: location_of CCO:B0016067 ! Q4G0Q6_HUMAN relationship: location_of CCO:B0016073 ! Q6P5R4_HUMAN relationship: location_of CCO:B0016986 ! P2RY8_HUMAN relationship: location_of CCO:B0017820 ! NOTC3_HUMAN relationship: location_of CCO:B0018438 ! CCRL1_HUMAN relationship: location_of CCO:B0018485 ! CLTR2_HUMAN relationship: location_of CCO:B0018486 ! CLTR1_HUMAN relationship: location_of CCO:B0018655 ! RYK_HUMAN relationship: location_of CCO:B0018695 ! EDNRA_HUMAN relationship: location_of CCO:B0018697 ! EDNRB_HUMAN relationship: location_of CCO:B0018778 ! M3K12_HUMAN relationship: location_of CCO:B0019510 ! TAOK3_HUMAN relationship: location_of CCO:B0019877 ! Q7KZS6_HUMAN relationship: location_of CCO:B0020052 ! CHIC2_HUMAN relationship: location_of CCO:B0020207 ! KCIP1_HUMAN relationship: location_of CCO:B0020218 ! CSEN_HUMAN relationship: location_of CCO:B0020371 ! BMR1B_HUMAN relationship: location_of CCO:B0020481 ! RET1G_HUMAN relationship: location_of CCO:B0020491 ! N2DL3_HUMAN relationship: location_of CCO:B0020561 ! PLD2_HUMAN relationship: location_of CCO:B0020591 ! RHOA_HUMAN relationship: location_of CCO:B0020594 ! RHOC_HUMAN relationship: location_of CCO:B0020605 ! GRIK3_HUMAN relationship: location_of CCO:B0020611 ! GRIK2_HUMAN relationship: location_of CCO:B0020614 ! GRIK1_HUMAN relationship: location_of CCO:B0020617 ! GRIK4_HUMAN relationship: location_of CCO:B0020623 ! GRIA4_HUMAN relationship: location_of CCO:B0020771 ! RGS3_HUMAN relationship: location_of CCO:B0020777 ! RGS13_HUMAN relationship: location_of CCO:B0020879 ! ADCY7_HUMAN relationship: location_of CCO:B0021202 ! A2A3C6_HUMAN relationship: location_of CCO:B0021203 ! A2A3C1_HUMAN relationship: location_of CCO:B0021208 ! A2A3C2_HUMAN relationship: location_of CCO:B0021209 ! A2A3C3_HUMAN relationship: location_of CCO:B0021210 ! BAI2_HUMAN relationship: location_of CCO:B0021417 ! CALRL_HUMAN relationship: location_of CCO:B0021419 ! A4D1G6_HUMAN relationship: location_of CCO:B0021435 ! ATF4_HUMAN relationship: location_of CCO:B0021696 ! CTGF_HUMAN relationship: location_of CCO:B0021887 ! I17RB_HUMAN relationship: location_of CCO:B0022071 ! TLR4_HUMAN relationship: location_of CCO:B0022455 ! KAP2_HUMAN relationship: location_of CCO:B0022559 ! SLAP2_HUMAN relationship: location_of CCO:B0022719 ! Q6IF88_HUMAN relationship: location_of CCO:B0022721 ! OR5K3_HUMAN relationship: location_of CCO:B0022723 ! OR5K1_HUMAN relationship: location_of CCO:B0022725 ! Q8NHB6_HUMAN relationship: location_of CCO:B0022726 ! O5AC2_HUMAN relationship: location_of CCO:B0022728 ! OR5H1_HUMAN relationship: location_of CCO:B0022729 ! O5H15_HUMAN relationship: location_of CCO:B0022731 ! OR5K2_HUMAN relationship: location_of CCO:B0022781 ! PIM1_HUMAN relationship: location_of CCO:B0022838 ! Q8NEI9_HUMAN relationship: location_of CCO:B0022839 ! Q8NHC0_HUMAN relationship: location_of CCO:B0022840 ! Q8NH98_HUMAN relationship: location_of CCO:B0022842 ! Q8NH65_HUMAN relationship: location_of CCO:B0022843 ! Q9UPJ0_HUMAN relationship: location_of CCO:B0022845 ! Q8NHB5_HUMAN relationship: location_of CCO:B0022847 ! Q8NH99_HUMAN relationship: location_of CCO:B0022849 ! Q8NH46_HUMAN relationship: location_of CCO:B0022852 ! Q8NGT4_HUMAN relationship: location_of CCO:B0022854 ! Q8NHC1_HUMAN relationship: location_of CCO:B0022857 ! Q8NHB9_HUMAN relationship: location_of CCO:B0022858 ! Q8NH45_HUMAN relationship: location_of CCO:B0022861 ! O7E24_HUMAN relationship: location_of CCO:B0022865 ! Q8NHA1_HUMAN relationship: location_of CCO:B0022866 ! Q8NG89_HUMAN relationship: location_of CCO:B0022870 ! Q96N54_HUMAN relationship: location_of CCO:B0022873 ! Q8NGD7_HUMAN relationship: location_of CCO:B0022899 ! GBRR2_HUMAN relationship: location_of CCO:B0022900 ! GBRG3_HUMAN relationship: location_of CCO:B0022901 ! GBRE_HUMAN relationship: location_of CCO:B0022903 ! GBRT_HUMAN relationship: location_of CCO:B0022906 ! GBRG1_HUMAN relationship: location_of CCO:B0022907 ! GBRA6_HUMAN relationship: location_of CCO:B0022909 ! GBRG2_HUMAN relationship: location_of CCO:B0022911 ! GLRB_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022914 ! GBRA1_HUMAN relationship: location_of CCO:B0022915 ! GBRA5_HUMAN relationship: location_of CCO:B0022917 ! GLRA2_HUMAN relationship: location_of CCO:B0022924 ! GBRA2_HUMAN relationship: location_of CCO:B0022926 ! GBRR1_HUMAN relationship: location_of CCO:B0022931 ! GBRD_HUMAN relationship: location_of CCO:B0022933 ! GBRA3_HUMAN relationship: location_of CCO:B0022999 ! PTPRK_HUMAN relationship: location_of CCO:B0023179 ! NPTN_HUMAN relationship: location_of CCO:B0023320 ! DLG2_HUMAN relationship: location_of CCO:B0023550 ! RAB5C_HUMAN relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0024306 ! PSYR_HUMAN relationship: location_of CCO:B0024308 ! GPR4_HUMAN relationship: location_of CCO:B0024407 ! RAP2C_HUMAN relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0024617 ! MMP2_HUMAN relationship: location_of CCO:B0025070 ! PDZD3_HUMAN relationship: location_of CCO:B0025169 ! TRPC1_HUMAN relationship: location_of CCO:B0025184 ! IL6RB_HUMAN relationship: location_of CCO:B0025350 ! DIRA1_HUMAN relationship: location_of CCO:B0025967 ! LRP6_HUMAN relationship: location_of CCO:B0026103 ! SORCN_HUMAN relationship: location_of CCO:B0026105 ! GRAN_HUMAN relationship: location_of CCO:B0026215 ! ITA2B_HUMAN relationship: location_of CCO:B0026218 ! ITAV_HUMAN relationship: location_of CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: location_of CCO:B0026726 ! MRGRF_HUMAN relationship: location_of CCO:B0026846 ! CNTFR_HUMAN relationship: location_of CCO:B0027555 ! O60726_HUMAN relationship: location_of CCO:B0027593 ! CDIPT_HUMAN relationship: location_of CCO:B0027730 ! SIN1_HUMAN relationship: location_of CCO:B0028201 ! OR1D2_HUMAN relationship: location_of CCO:B0028290 ! JAG1_HUMAN relationship: location_of CCO:B0028292 ! DLL1_HUMAN relationship: location_of CCO:B0028914 ! AB1IP_HUMAN relationship: location_of CCO:B0029013 ! OR9I1_HUMAN relationship: location_of CCO:B0029014 ! Q6IF62_HUMAN relationship: location_of CCO:B0029015 ! OR5W2_HUMAN relationship: location_of CCO:B0029017 ! OR5B3_HUMAN relationship: location_of CCO:B0029019 ! Q8NH91_HUMAN relationship: location_of CCO:B0029022 ! OR8K5_HUMAN relationship: location_of CCO:B0029023 ! OR5L1_HUMAN relationship: location_of CCO:B0029024 ! OR5B2_HUMAN relationship: location_of CCO:B0029025 ! OR8U1_HUMAN relationship: location_of CCO:B0029027 ! A8MUX1_HUMAN relationship: location_of CCO:B0029028 ! OR5BC_HUMAN relationship: location_of CCO:B0029029 ! OR5R1_HUMAN relationship: location_of CCO:B0029030 ! OR5C1_HUMAN relationship: location_of CCO:B0029031 ! OR8G5_HUMAN relationship: location_of CCO:B0029033 ! OR5J2_HUMAN relationship: location_of CCO:B0029034 ! OR8D4_HUMAN relationship: location_of CCO:B0029035 ! O5AR1_HUMAN relationship: location_of CCO:B0029036 ! Q6IFM9_HUMAN relationship: location_of CCO:B0029037 ! A8MXK6_HUMAN relationship: location_of CCO:B0029038 ! O5AS1_HUMAN relationship: location_of CCO:B0029039 ! OR5BH_HUMAN relationship: location_of CCO:B0029040 ! OR5L2_HUMAN relationship: location_of CCO:B0029727 ! CEAM1_HUMAN relationship: location_of CCO:B0030164 ! TLR1_HUMAN relationship: location_of CCO:B0030165 ! TLR10_HUMAN relationship: location_of CCO:B0030171 ! TLR2_HUMAN relationship: location_of CCO:B0030172 ! TLR6_HUMAN relationship: location_of CCO:B0030249 ! GNAZ_HUMAN relationship: location_of CCO:B0030251 ! GNA11_HUMAN relationship: location_of CCO:B0030278 ! RND1_HUMAN relationship: location_of CCO:B0030280 ! RND2_HUMAN relationship: location_of CCO:B0030552 ! MC3R_HUMAN relationship: location_of CCO:B0030561 ! MSHR_HUMAN relationship: location_of CCO:B0030569 ! MC5R_HUMAN relationship: location_of CCO:B0030574 ! MC4R_HUMAN relationship: location_of CCO:B0030577 ! ACTHR_HUMAN relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: location_of CCO:B0031296 ! AT1B1_HUMAN-Phosphotyrosine101 relationship: location_of CCO:B0031317 ! FGFR3_HUMAN-Phosphotyrosine647 relationship: location_of CCO:B0031337 ! LYN_HUMAN-Phosphotyrosine194 relationship: location_of CCO:B0031342 ! MYO16_HUMAN-Phosphotyrosine1432 relationship: location_of CCO:B0031499 ! GBP2_HUMAN relationship: location_of CCO:B0031540 ! APC2_HUMAN relationship: location_of CCO:B0031878 ! VWF_HUMAN relationship: location_of CCO:B0032345 ! Q5Y190_HUMAN relationship: location_of CCO:B0032349 ! CELR2_HUMAN relationship: location_of CCO:B0032391 ! MTND_HUMAN relationship: location_of CCO:B0032548 ! RAB8A_HUMAN relationship: location_of CCO:B0032549 ! RAB10_HUMAN relationship: location_of CCO:B0032550 ! RAB8B_HUMAN relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0032799 ! ACHB3_HUMAN relationship: location_of CCO:B0032804 ! ACHA3_HUMAN relationship: location_of CCO:B0032806 ! ACHA5_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0032809 ! ACHA2_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0033141 ! ITB3_HUMAN relationship: location_of CCO:B0033335 ! Q6IFC7_HUMAN relationship: location_of CCO:B0033338 ! OR5T1_HUMAN relationship: location_of CCO:B0033340 ! O5AK3_HUMAN relationship: location_of CCO:B0033341 ! OR5K4_HUMAN relationship: location_of CCO:B0033342 ! A8MWJ9_HUMAN relationship: location_of CCO:B0033343 ! Q6IFC8_HUMAN relationship: location_of CCO:B0033344 ! OR9Q2_HUMAN relationship: location_of CCO:B0033345 ! A8MXY9_HUMAN relationship: location_of CCO:B0033346 ! OR5I1_HUMAN relationship: location_of CCO:B0033347 ! O5AC1_HUMAN relationship: location_of CCO:B0033348 ! A8MVK2_HUMAN relationship: location_of CCO:B0033349 ! O5H14_HUMAN relationship: location_of CCO:B0033351 ! Q8IXE7_HUMAN relationship: location_of CCO:B0033402 ! Q14CE0_HUMAN relationship: location_of CCO:B0033403 ! Q6F3F5_HUMAN relationship: location_of CCO:B0033404 ! Q6F3F6_HUMAN relationship: location_of CCO:B0033406 ! A2A2J1_HUMAN relationship: location_of CCO:B0033407 ! A2A2J2_HUMAN relationship: location_of CCO:B0033410 ! A9Z1X2_HUMAN relationship: location_of CCO:B0033411 ! Q6F3F8_HUMAN relationship: location_of CCO:B0033412 ! GP112_HUMAN relationship: location_of CCO:B0033414 ! Q499H0_HUMAN relationship: location_of CCO:B0033415 ! Q5EGP2_HUMAN relationship: location_of CCO:B0033418 ! GPR64_HUMAN relationship: location_of CCO:B0033419 ! Q6F3F7_HUMAN relationship: location_of CCO:B0033477 ! LRP8_HUMAN relationship: location_of CCO:B0033689 ! Q8TD27_HUMAN relationship: location_of CCO:B0034023 ! S26A5_HUMAN relationship: location_of CCO:B0034552 ! ANPRB_HUMAN-Phosphoserine518 relationship: location_of CCO:B0034706 ! DLG4_HUMAN-Phosphotyrosine432 relationship: location_of CCO:B0034734 ! EPHA3_HUMAN-Phosphotyrosine596 relationship: location_of CCO:B0034756 ! EPHB1_HUMAN-Phosphotyrosine594 relationship: location_of CCO:B0034813 ! FPR1_HUMAN-Phosphothreonine339 relationship: location_of CCO:B0034822 ! G3BP1_HUMAN-Omega-N-methylated arginine460 relationship: location_of CCO:B0034880 ! IQGA1_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0034889 ! ITB2_HUMAN-Phosphothreonine759 relationship: location_of CCO:B0035046 ! KPCB_HUMAN-Phosphothreonine504 relationship: location_of CCO:B0035082 ! L1CAM_HUMAN-Phosphoserine1248 relationship: location_of CCO:B0035087 ! LANC2_HUMAN-Phosphotyrosine295 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035292 ! NMDE4_HUMAN-Phosphoserine1326 relationship: location_of CCO:B0035307 ! NRCAM_HUMAN-Phosphoserine427 relationship: location_of CCO:B0035358 ! PECA1_HUMAN-Phosphotyrosine713 relationship: location_of CCO:B0035507 ! RAP1B_HUMAN-ADP-ribosylserine39 relationship: location_of CCO:B0035510 ! RAP2A_HUMAN-Cysteine methyl ester180 relationship: location_of CCO:B0035511 ! RAP2B_HUMAN-Cysteine methyl ester180 relationship: location_of CCO:B0035564 ! RGS1_HUMAN-Phosphothreonine167 relationship: location_of CCO:B0035599 ! RRAS2_HUMAN-Cysteine methyl ester201 relationship: location_of CCO:B0035600 ! RRAS_HUMAN-Cysteine methyl ester215 relationship: location_of CCO:B0035817 ! TRPC4_HUMAN-Phosphoserine195 relationship: location_of CCO:B0035937 ! S26A8_HUMAN relationship: location_of CCO:B0036600 ! NKG2A_HUMAN relationship: location_of CCO:B0037083 ! RXFP2_HUMAN relationship: location_of CCO:B0037085 ! RXFP1_HUMAN relationship: location_of CCO:B0037229 ! PE2R3_HUMAN relationship: location_of CCO:B0037398 ! PXK_HUMAN relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0038260 ! 5HT2C_HUMAN relationship: location_of CCO:B0038262 ! HRH2_HUMAN relationship: location_of CCO:B0038263 ! ADA1B_HUMAN relationship: location_of CCO:B0038265 ! ADA1D_HUMAN relationship: location_of CCO:B0038266 ! 5HT1D_HUMAN relationship: location_of CCO:B0038267 ! ADA2B_HUMAN relationship: location_of CCO:B0038438 ! RB11A_HUMAN relationship: location_of CCO:B0038563 ! ADA11_HUMAN relationship: location_of CCO:B0038590 ! Q6IFJ9_HUMAN relationship: location_of CCO:B0038591 ! Q8NG79_HUMAN relationship: location_of CCO:B0038592 ! OR6M1_HUMAN relationship: location_of CCO:B0038734 ! DPP4_HUMAN relationship: location_of CCO:B0038854 ! FZD5_HUMAN relationship: location_of CCO:B0038856 ! FZD7_HUMAN relationship: location_of CCO:B0038861 ! FZD9_HUMAN relationship: location_of CCO:B0038878 ! CSF1_HUMAN relationship: location_of CCO:B0038926 ! TRPV4_HUMAN relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0039298 ! ADA1A_HUMAN-Phosphoserine215 relationship: location_of CCO:B0039339 ! CAP2_HUMAN-Phosphoserine301 relationship: location_of CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: location_of CCO:B0039507 ! MARK2_HUMAN-Phosphothreonine208 relationship: location_of CCO:B0039518 ! MAST1_HUMAN-Phosphoserine161 relationship: location_of CCO:B0039588 ! PLS1_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0039596 ! PREX1_HUMAN-Phosphoserine436 relationship: location_of CCO:B0039613 ! RB11B_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0039618 ! RGPS2_HUMAN-Phosphoserine343 relationship: location_of CCO:B0039677 ! TGFR1_HUMAN-Phosphoserine191 relationship: location_of CCO:B0039687 ! TRPV1_HUMAN-Phosphoserine775 relationship: location_of CCO:B0039936 ! RHEB_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0039988 ! PP16A_HUMAN-Phosphotyrosine434 relationship: location_of CCO:B0040684 ! REBL1_HUMAN relationship: location_of CCO:B0041173 ! RASH_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041523 ! ANK1_HUMAN relationship: location_of CCO:B0041800 ! CAN1_HUMAN relationship: location_of CCO:B0041821 ! CAN2_HUMAN relationship: location_of CCO:B0042222 ! GRM3_HUMAN relationship: location_of CCO:B0042225 ! GRM4_HUMAN relationship: location_of CCO:B0042226 ! Q8N0Z0_HUMAN relationship: location_of CCO:B0042227 ! GRM7_HUMAN relationship: location_of CCO:B0042228 ! A4D0Y3_HUMAN relationship: location_of CCO:B0042229 ! Q8NHA9_HUMAN relationship: location_of CCO:B0042230 ! GRM5_HUMAN relationship: location_of CCO:B0042237 ! Q86YG3_HUMAN relationship: location_of CCO:B0042238 ! Q6J164_HUMAN relationship: location_of CCO:B0042239 ! GRM2_HUMAN relationship: location_of CCO:B0042241 ! GRM8_HUMAN relationship: location_of CCO:B0042244 ! GRM6_HUMAN relationship: location_of CCO:B0042246 ! A8K1R9_HUMAN relationship: location_of CCO:B0042251 ! Q6ZMQ2_HUMAN relationship: location_of CCO:B0042255 ! Q59HC2_HUMAN relationship: location_of CCO:B0042293 ! ACHG_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0042813 ! IL2RB_HUMAN relationship: location_of CCO:B0042830 ! FCERA_HUMAN relationship: location_of CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 relationship: location_of CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0043460 ! CENA1_HUMAN-Phosphothreonine276 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0043552 ! PI51A_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0043817 ! NGX6_HUMAN relationship: location_of CCO:B0043866 ! LPAR2_HUMAN relationship: location_of CCO:B0043867 ! LPAR4_HUMAN relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0048898 ! RGPS1_HUMAN relationship: location_of CCO:B0048954 ! IL31R_HUMAN relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0049157 ! PAR4_HUMAN relationship: location_of CCO:B0049161 ! PAR2_HUMAN relationship: location_of CCO:B0049305 ! TVA3_HUMAN relationship: location_of CCO:B0049445 ! A6NEW7_HUMAN relationship: location_of CCO:B0049448 ! Q53TQ2_HUMAN relationship: location_of CCO:B0049452 ! NK2R_HUMAN relationship: location_of CCO:B0049455 ! NK3R_HUMAN relationship: location_of CCO:B0049457 ! NK1R_HUMAN relationship: location_of CCO:B0049698 ! CLD7_HUMAN relationship: location_of CCO:B0049806 ! OR8H1_HUMAN relationship: location_of CCO:B0049809 ! A8MYY4_HUMAN relationship: location_of CCO:B0049813 ! OR8B4_HUMAN relationship: location_of CCO:B0049814 ! OR8H3_HUMAN relationship: location_of CCO:B0049816 ! OR8H2_HUMAN relationship: location_of CCO:B0049817 ! OR5MB_HUMAN relationship: location_of CCO:B0049915 ! RAMP3_HUMAN relationship: location_of CCO:B0050196 ! ITA2_HUMAN relationship: location_of CCO:B0050202 ! ITAL_HUMAN relationship: location_of CCO:B0050612 ! NCKP1_HUMAN relationship: location_of CCO:B0050753 ! OPRD_HUMAN relationship: location_of CCO:B0050755 ! SSR2_HUMAN relationship: location_of CCO:B0050758 ! OPRK_HUMAN relationship: location_of CCO:B0050764 ! NPBW2_HUMAN relationship: location_of CCO:B0050781 ! OPRX_HUMAN relationship: location_of CCO:B0050782 ! NPBW1_HUMAN relationship: location_of CCO:B0050788 ! SSR1_HUMAN relationship: location_of CCO:B0050793 ! SSR4_HUMAN relationship: location_of CCO:B0050794 ! SSR3_HUMAN relationship: location_of CCO:B0051475 ! MOT3_HUMAN relationship: location_of CCO:B0051877 ! OR8D2_HUMAN relationship: location_of CCO:B0051880 ! OR8G1_HUMAN relationship: location_of CCO:B0051882 ! OR8G2_HUMAN relationship: location_of CCO:B0051883 ! OR8U9_HUMAN relationship: location_of CCO:B0051887 ! O5AK2_HUMAN relationship: location_of CCO:B0051892 ! OR8U8_HUMAN relationship: location_of CCO:B0051893 ! O5AP2_HUMAN relationship: location_of CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0052321 ! CEAM6_HUMAN-Phosphoserine243 relationship: location_of CCO:B0052407 ! GNA14_HUMAN-ADP-ribosylarginine179 relationship: location_of CCO:B0052463 ! IRS1_HUMAN-Phosphotyrosine632 relationship: location_of CCO:B0052500 ! IRS4_HUMAN-Phosphotyrosine921 relationship: location_of CCO:B0052646 ! PLEC1_HUMAN-Phosphoserine4382 relationship: location_of CCO:B0052794 ! SSR5_HUMAN-Phosphoserine325 relationship: location_of CCO:B0052833 ! TGM2_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0053696 ! A0A502_HUMAN relationship: location_of CCO:B0053705 ! RHG10_HUMAN relationship: location_of CCO:B0053724 ! A2BDZ0_HUMAN relationship: location_of CCO:B0053725 ! A2BDZ2_HUMAN relationship: location_of CCO:B0053726 ! A2BEC2_HUMAN relationship: location_of CCO:B0053727 ! A2BF33_HUMAN relationship: location_of CCO:B0053728 ! A2BF34_HUMAN relationship: location_of CCO:B0053742 ! OR2M5_HUMAN relationship: location_of CCO:B0053752 ! RAB19_HUMAN relationship: location_of CCO:B0053759 ! O2A25_HUMAN relationship: location_of CCO:B0053786 ! O6C74_HUMAN relationship: location_of CCO:B0053788 ! O14I1_HUMAN relationship: location_of CCO:B0053793 ! O6C68_HUMAN relationship: location_of CCO:B0053800 ! A6NE11_HUMAN relationship: location_of CCO:B0053805 ! A6NE96_HUMAN relationship: location_of CCO:B0053816 ! OR6C6_HUMAN relationship: location_of CCO:B0053824 ! A6NFR0_HUMAN relationship: location_of CCO:B0053827 ! A6NG39_HUMAN relationship: location_of CCO:B0053835 ! O51F1_HUMAN relationship: location_of CCO:B0053836 ! OR2T8_HUMAN relationship: location_of CCO:B0053842 ! A6NH69_HUMAN relationship: location_of CCO:B0053845 ! O4C46_HUMAN relationship: location_of CCO:B0053862 ! O6C70_HUMAN relationship: location_of CCO:B0053875 ! O6C65_HUMAN relationship: location_of CCO:B0053890 ! O6C75_HUMAN relationship: location_of CCO:B0053892 ! OR5BL_HUMAN relationship: location_of CCO:B0053893 ! A6NL96_HUMAN relationship: location_of CCO:B0053902 ! O2AG2_HUMAN relationship: location_of CCO:B0053904 ! O6C76_HUMAN relationship: location_of CCO:B0053908 ! O52A4_HUMAN relationship: location_of CCO:B0053910 ! O4C45_HUMAN relationship: location_of CCO:B0053914 ! O2AT4_HUMAN relationship: location_of CCO:B0053959 ! A8K2Y6_HUMAN relationship: location_of CCO:B0053966 ! A8K4E4_HUMAN relationship: location_of CCO:B0053973 ! A8K6W1_HUMAN relationship: location_of CCO:B0054001 ! A8MQV3_HUMAN relationship: location_of CCO:B0054018 ! A8MSZ9_HUMAN relationship: location_of CCO:B0054049 ! A8MUW4_HUMAN relationship: location_of CCO:B0054061 ! A8MVM5_HUMAN relationship: location_of CCO:B0054095 ! A8MXE9_HUMAN relationship: location_of CCO:B0054097 ! A8MXI2_HUMAN relationship: location_of CCO:B0054104 ! A8MXU4_HUMAN relationship: location_of CCO:B0054108 ! A8MXZ2_HUMAN relationship: location_of CCO:B0054116 ! A8MY83_HUMAN relationship: location_of CCO:B0054186 ! B0UY34_HUMAN relationship: location_of CCO:B0054241 ! B1ALU1_HUMAN relationship: location_of CCO:B0054242 ! B1ALU2_HUMAN relationship: location_of CCO:B0054243 ! B1ALU3_HUMAN relationship: location_of CCO:B0054244 ! B1ALU4_HUMAN relationship: location_of CCO:B0054245 ! B1ALU5_HUMAN relationship: location_of CCO:B0054278 ! B1AWB3_HUMAN relationship: location_of CCO:B0054279 ! B1AWB4_HUMAN relationship: location_of CCO:B0054280 ! B1AWB6_HUMAN relationship: location_of CCO:B0054281 ! B1AWB7_HUMAN relationship: location_of CCO:B0054291 ! GPR25_HUMAN relationship: location_of CCO:B0054300 ! RHOD_HUMAN relationship: location_of CCO:B0054306 ! GPR31_HUMAN relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054316 ! P2Y10_HUMAN relationship: location_of CCO:B0054318 ! CCRL2_HUMAN relationship: location_of CCO:B0054321 ! GFRA2_HUMAN relationship: location_of CCO:B0054333 ! CXCR6_HUMAN relationship: location_of CCO:B0054335 ! CCBP2_HUMAN relationship: location_of CCO:B0054336 ! PODXL_HUMAN relationship: location_of CCO:B0054344 ! LPP1_HUMAN relationship: location_of CCO:B0054347 ! SOCS7_HUMAN relationship: location_of CCO:B0054348 ! BAI1_HUMAN relationship: location_of CCO:B0054353 ! OR7AH_HUMAN relationship: location_of CCO:B0054356 ! GBGT2_HUMAN relationship: location_of CCO:B0054357 ! BORG1_HUMAN relationship: location_of CCO:B0054360 ! GP171_HUMAN relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0054368 ! O14694_HUMAN relationship: location_of CCO:B0054373 ! TR10B_HUMAN relationship: location_of CCO:B0054375 ! TNF11_HUMAN relationship: location_of CCO:B0054378 ! TAAR5_HUMAN relationship: location_of CCO:B0054379 ! RASM_HUMAN relationship: location_of CCO:B0054383 ! FFAR3_HUMAN relationship: location_of CCO:B0054394 ! RAB7L_HUMAN relationship: location_of CCO:B0054403 ! MCF2L_HUMAN relationship: location_of CCO:B0054417 ! GP182_HUMAN relationship: location_of CCO:B0054432 ! GPR37_HUMAN relationship: location_of CCO:B0054444 ! GPR42_HUMAN relationship: location_of CCO:B0054448 ! FFAR2_HUMAN relationship: location_of CCO:B0054451 ! PLXB1_HUMAN relationship: location_of CCO:B0054459 ! MTLR_HUMAN relationship: location_of CCO:B0054460 ! GPR39_HUMAN relationship: location_of CCO:B0054478 ! RASL2_HUMAN relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0054484 ! TNF12_HUMAN relationship: location_of CCO:B0054490 ! TNF14_HUMAN relationship: location_of CCO:B0054498 ! GALR2_HUMAN relationship: location_of CCO:B0054499 ! SPY1_HUMAN relationship: location_of CCO:B0054503 ! OX2R_HUMAN relationship: location_of CCO:B0054511 ! AKA7A_HUMAN relationship: location_of CCO:B0054516 ! CYH3_HUMAN relationship: location_of CCO:B0054518 ! OR1F1_HUMAN relationship: location_of CCO:B0054528 ! OR2T1_HUMAN relationship: location_of CCO:B0054537 ! GBG7_HUMAN relationship: location_of CCO:B0054552 ! O10H2_HUMAN relationship: location_of CCO:B0054553 ! O10H3_HUMAN relationship: location_of CCO:B0054555 ! OR7C2_HUMAN relationship: location_of CCO:B0054558 ! OR1I1_HUMAN relationship: location_of CCO:B0054561 ! PLXC1_HUMAN relationship: location_of CCO:B0054570 ! GFRA3_HUMAN relationship: location_of CCO:B0054576 ! GALR3_HUMAN relationship: location_of CCO:B0054587 ! RAMP1_HUMAN relationship: location_of CCO:B0054592 ! LIRA1_HUMAN relationship: location_of CCO:B0054602 ! ROCK2_HUMAN relationship: location_of CCO:B0054629 ! TULP3_HUMAN relationship: location_of CCO:B0054630 ! GPR32_HUMAN relationship: location_of CCO:B0054640 ! LGR5_HUMAN relationship: location_of CCO:B0054643 ! GPC4_HUMAN relationship: location_of CCO:B0054675 ! O75889_HUMAN relationship: location_of CCO:B0054684 ! OR2B3_HUMAN relationship: location_of CCO:B0054685 ! OR2J3_HUMAN relationship: location_of CCO:B0054686 ! OR2J2_HUMAN relationship: location_of CCO:B0054688 ! NCTR1_HUMAN relationship: location_of CCO:B0054694 ! OR7C1_HUMAN relationship: location_of CCO:B0054695 ! OR7AA_HUMAN relationship: location_of CCO:B0054709 ! DKK1_HUMAN relationship: location_of CCO:B0054715 ! OR2F2_HUMAN relationship: location_of CCO:B0054716 ! O4F21_HUMAN relationship: location_of CCO:B0054717 ! OR2A4_HUMAN relationship: location_of CCO:B0054727 ! S1PR2_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054736 ! OR5F1_HUMAN relationship: location_of CCO:B0054737 ! OR6A2_HUMAN relationship: location_of CCO:B0054752 ! OR2C1_HUMAN relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: location_of CCO:B0054767 ! LPHN2_HUMAN relationship: location_of CCO:B0054768 ! VNN1_HUMAN relationship: location_of CCO:B0054780 ! NTR2_HUMAN relationship: location_of CCO:B0054784 ! LY86_HUMAN relationship: location_of CCO:B0054785 ! RAB3D_HUMAN relationship: location_of CCO:B0054794 ! GPR75_HUMAN relationship: location_of CCO:B0054804 ! OR2H2_HUMAN relationship: location_of CCO:B0054807 ! NCTR2_HUMAN relationship: location_of CCO:B0054811 ! BY55_HUMAN relationship: location_of CCO:B0054813 ! S1PR4_HUMAN relationship: location_of CCO:B0054827 ! UROK_HUMAN relationship: location_of CCO:B0054837 ! PDYN_HUMAN relationship: location_of CCO:B0054856 ! CD8A_HUMAN relationship: location_of CCO:B0054858 ! 2B32_HUMAN relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054866 ! FIBB_HUMAN relationship: location_of CCO:B0054867 ! FIBG_HUMAN relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0054872 ! AMBP_HUMAN relationship: location_of CCO:B0054884 ! PROC_HUMAN relationship: location_of CCO:B0054888 ! MAS_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054916 ! CD3E_HUMAN relationship: location_of CCO:B0054917 ! UROM_HUMAN relationship: location_of CCO:B0054920 ! CO1A2_HUMAN relationship: location_of CCO:B0054921 ! TNR16_HUMAN relationship: location_of CCO:B0054928 ! CD14_HUMAN relationship: location_of CCO:B0054929 ! ADRB1_HUMAN relationship: location_of CCO:B0054934 ! 5HT1A_HUMAN relationship: location_of CCO:B0054937 ! ADA2A_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0054946 ! CD7_HUMAN relationship: location_of CCO:B0054953 ! RB40L_HUMAN relationship: location_of CCO:B0054955 ! OR4A8_HUMAN relationship: location_of CCO:B0054956 ! O5AL1_HUMAN relationship: location_of CCO:B0054957 ! OR4Q2_HUMAN relationship: location_of CCO:B0054958 ! OR5G3_HUMAN relationship: location_of CCO:B0054959 ! O10J4_HUMAN relationship: location_of CCO:B0054960 ! OR4E1_HUMAN relationship: location_of CCO:B0054961 ! O52Z1_HUMAN relationship: location_of CCO:B0054964 ! OR9G9_HUMAN relationship: location_of CCO:B0054983 ! CD8B_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0054988 ! RALA_HUMAN relationship: location_of CCO:B0054989 ! RALB_HUMAN relationship: location_of CCO:B0054995 ! CD20_HUMAN relationship: location_of CCO:B0055006 ! ACE_HUMAN relationship: location_of CCO:B0055020 ! ADRB3_HUMAN relationship: location_of CCO:B0055024 ! DRD2_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055051 ! EPB42_HUMAN relationship: location_of CCO:B0055054 ! TSHR_HUMAN relationship: location_of CCO:B0055104 ! ADA2C_HUMAN relationship: location_of CCO:B0055108 ! CD53_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055124 ! NTF3_HUMAN relationship: location_of CCO:B0055133 ! CNR1_HUMAN relationship: location_of CCO:B0055135 ! SCF_HUMAN relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0055138 ! TA2R_HUMAN relationship: location_of CCO:B0055139 ! DRD4_HUMAN relationship: location_of CCO:B0055140 ! DRD5_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055145 ! ENPP1_HUMAN relationship: location_of CCO:B0055147 ! FGFR4_HUMAN relationship: location_of CCO:B0055152 ! LSHR_HUMAN relationship: location_of CCO:B0055172 ! AKAP5_HUMAN relationship: location_of CCO:B0055175 ! CXCR1_HUMAN relationship: location_of CCO:B0055177 ! CD24_HUMAN relationship: location_of CCO:B0055178 ! FPR3_HUMAN relationship: location_of CCO:B0055179 ! FPR2_HUMAN relationship: location_of CCO:B0055181 ! PTAFR_HUMAN relationship: location_of CCO:B0055182 ! CXCR7_HUMAN relationship: location_of CCO:B0055187 ! NPY1R_HUMAN relationship: location_of CCO:B0055188 ! TNR5_HUMAN relationship: location_of CCO:B0055197 ! 5HT1B_HUMAN relationship: location_of CCO:B0055198 ! 5HT2A_HUMAN relationship: location_of CCO:B0055201 ! NMBR_HUMAN relationship: location_of CCO:B0055205 ! 5HT1E_HUMAN relationship: location_of CCO:B0055207 ! CD38_HUMAN relationship: location_of CCO:B0055210 ! AA2AR_HUMAN relationship: location_of CCO:B0055211 ! AA2BR_HUMAN relationship: location_of CCO:B0055218 ! BKRB2_HUMAN relationship: location_of CCO:B0055219 ! V2R_HUMAN relationship: location_of CCO:B0055221 ! AA1R_HUMAN relationship: location_of CCO:B0055222 ! GRPR_HUMAN relationship: location_of CCO:B0055223 ! AGTR1_HUMAN relationship: location_of CCO:B0055224 ! OXYR_HUMAN relationship: location_of CCO:B0055226 ! 5HT1F_HUMAN relationship: location_of CCO:B0055227 ! OR1E1_HUMAN relationship: location_of CCO:B0055228 ! O10J1_HUMAN relationship: location_of CCO:B0055229 ! GNRHR_HUMAN relationship: location_of CCO:B0055230 ! CALCR_HUMAN relationship: location_of CCO:B0055231 ! NTR1_HUMAN relationship: location_of CCO:B0055247 ! FCG2B_HUMAN relationship: location_of CCO:B0055250 ! ARRB2_HUMAN relationship: location_of CCO:B0055251 ! CCKAR_HUMAN relationship: location_of CCO:B0055252 ! GASR_HUMAN relationship: location_of CCO:B0055256 ! CCR1_HUMAN relationship: location_of CCO:B0055257 ! BRS3_HUMAN relationship: location_of CCO:B0055258 ! CCR7_HUMAN relationship: location_of CCO:B0055260 ! CXCR5_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055262 ! CD70_HUMAN relationship: location_of CCO:B0055265 ! LSP1_HUMAN relationship: location_of CCO:B0055268 ! CD80_HUMAN relationship: location_of CCO:B0055271 ! GRK5_HUMAN relationship: location_of CCO:B0055272 ! 5HT7R_HUMAN relationship: location_of CCO:B0055273 ! CNR2_HUMAN relationship: location_of CCO:B0055274 ! TRFR_HUMAN relationship: location_of CCO:B0055275 ! PE2R1_HUMAN relationship: location_of CCO:B0055276 ! CRFR1_HUMAN relationship: location_of CCO:B0055288 ! PE2R4_HUMAN relationship: location_of CCO:B0055289 ! MAS1L_HUMAN relationship: location_of CCO:B0055290 ! APJ_HUMAN relationship: location_of CCO:B0055293 ! DRD3_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055318 ! V1AR_HUMAN relationship: location_of CCO:B0055325 ! ADCY8_HUMAN relationship: location_of CCO:B0055328 ! CD79B_HUMAN relationship: location_of CCO:B0055335 ! CASR_HUMAN relationship: location_of CCO:B0055338 ! P2RY2_HUMAN relationship: location_of CCO:B0055341 ! PACR_HUMAN relationship: location_of CCO:B0055342 ! VIPR2_HUMAN relationship: location_of CCO:B0055343 ! 5HT2B_HUMAN relationship: location_of CCO:B0055346 ! CD86_HUMAN relationship: location_of CCO:B0055351 ! CASP3_HUMAN relationship: location_of CCO:B0055355 ! LIFR_HUMAN relationship: location_of CCO:B0055358 ! PF2R_HUMAN relationship: location_of CCO:B0055359 ! PE2R2_HUMAN relationship: location_of CCO:B0055367 ! P2RY5_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055372 ! GPR3_HUMAN relationship: location_of CCO:B0055373 ! GPR1_HUMAN relationship: location_of CCO:B0055374 ! XCR1_HUMAN relationship: location_of CCO:B0055378 ! BKRB1_HUMAN relationship: location_of CCO:B0055382 ! GALR1_HUMAN relationship: location_of CCO:B0055388 ! OR3A1_HUMAN relationship: location_of CCO:B0055389 ! OR3A4_HUMAN relationship: location_of CCO:B0055390 ! OR1G1_HUMAN relationship: location_of CCO:B0055391 ! OR3A2_HUMAN relationship: location_of CCO:B0055393 ! 5HT5A_HUMAN relationship: location_of CCO:B0055395 ! V1BR_HUMAN relationship: location_of CCO:B0055398 ! TNFL6_HUMAN relationship: location_of CCO:B0055406 ! INAR2_HUMAN relationship: location_of CCO:B0055413 ! CD97_HUMAN relationship: location_of CCO:B0055414 ! G109B_HUMAN relationship: location_of CCO:B0055418 ! NPY2R_HUMAN relationship: location_of CCO:B0055419 ! PTH2R_HUMAN relationship: location_of CCO:B0055420 ! CX3C1_HUMAN relationship: location_of CCO:B0055428 ! CXCR3_HUMAN relationship: location_of CCO:B0055429 ! PRLHR_HUMAN relationship: location_of CCO:B0055430 ! GPR15_HUMAN relationship: location_of CCO:B0055435 ! FLT3L_HUMAN relationship: location_of CCO:B0055442 ! AGTR2_HUMAN relationship: location_of CCO:B0055443 ! GBG4_HUMAN relationship: location_of CCO:B0055444 ! GBG10_HUMAN relationship: location_of CCO:B0055447 ! NPY4R_HUMAN relationship: location_of CCO:B0055449 ! 5HT6R_HUMAN relationship: location_of CCO:B0055456 ! LU_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055459 ! RAB28_HUMAN relationship: location_of CCO:B0055460 ! PDE6C_HUMAN relationship: location_of CCO:B0055468 ! P2RX1_HUMAN relationship: location_of CCO:B0055472 ! CCR3_HUMAN relationship: location_of CCO:B0055473 ! CCR4_HUMAN relationship: location_of CCO:B0055474 ! CCR5_HUMAN relationship: location_of CCO:B0055475 ! CCR6_HUMAN relationship: location_of CCO:B0055476 ! CCR8_HUMAN relationship: location_of CCO:B0055477 ! CCR9_HUMAN relationship: location_of CCO:B0055508 ! ARFP2_HUMAN relationship: location_of CCO:B0055510 ! AP2S1_HUMAN relationship: location_of CCO:B0055523 ! GEM_HUMAN relationship: location_of CCO:B0055533 ! CADH4_HUMAN relationship: location_of CCO:B0055534 ! CAD13_HUMAN relationship: location_of CCO:B0055538 ! GFRA1_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0055560 ! RAB25_HUMAN relationship: location_of CCO:B0055565 ! OR2B6_HUMAN relationship: location_of CCO:B0055566 ! OR4D2_HUMAN relationship: location_of CCO:B0055567 ! O10A3_HUMAN relationship: location_of CCO:B0055568 ! O12D2_HUMAN relationship: location_of CCO:B0055572 ! TIRAP_HUMAN relationship: location_of CCO:B0055592 ! OR2B8_HUMAN relationship: location_of CCO:B0055599 ! GPR85_HUMAN relationship: location_of CCO:B0055601 ! RAB4B_HUMAN relationship: location_of CCO:B0055614 ! GBG11_HUMAN relationship: location_of CCO:B0055616 ! ARF6_HUMAN relationship: location_of CCO:B0055625 ! POK4_HUMAN relationship: location_of CCO:B0055631 ! GBG1_HUMAN relationship: location_of CCO:B0055632 ! GBG3_HUMAN relationship: location_of CCO:B0055633 ! GBG5_HUMAN relationship: location_of CCO:B0055639 ! ACCN2_HUMAN relationship: location_of CCO:B0055645 ! X3CL1_HUMAN relationship: location_of CCO:B0055652 ! I13R1_HUMAN relationship: location_of CCO:B0055662 ! ARF5_HUMAN relationship: location_of CCO:B0055669 ! VLDLR_HUMAN relationship: location_of CCO:B0055686 ! IL9R_HUMAN relationship: location_of CCO:B0055687 ! CD83_HUMAN relationship: location_of CCO:B0055691 ! ILRL1_HUMAN relationship: location_of CCO:B0055697 ! SC6A3_HUMAN relationship: location_of CCO:B0055699 ! ROR1_HUMAN relationship: location_of CCO:B0055707 ! TNR17_HUMAN relationship: location_of CCO:B0055713 ! GHRHR_HUMAN relationship: location_of CCO:B0055715 ! TIE2_HUMAN relationship: location_of CCO:B0055721 ! GNA12_HUMAN relationship: location_of CCO:B0055723 ! UPAR_HUMAN relationship: location_of CCO:B0055724 ! PTHR1_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055738 ! MUC24_HUMAN relationship: location_of CCO:B0055740 ! PLP2_HUMAN relationship: location_of CCO:B0055781 ! AMPE_HUMAN relationship: location_of CCO:B0055793 ! CD47_HUMAN relationship: location_of CCO:B0055836 ! BST2_HUMAN relationship: location_of CCO:B0055845 ! RB40B_HUMAN relationship: location_of CCO:B0055851 ! CNTN1_HUMAN relationship: location_of CCO:B0055857 ! KLRB1_HUMAN relationship: location_of CCO:B0055889 ! KLRD1_HUMAN relationship: location_of CCO:B0055890 ! PD2R_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055895 ! GPR17_HUMAN relationship: location_of CCO:B0055898 ! CRFR2_HUMAN relationship: location_of CCO:B0055907 ! ILK_HUMAN relationship: location_of CCO:B0055909 ! TMED1_HUMAN relationship: location_of CCO:B0055912 ! MADCA_HUMAN relationship: location_of CCO:B0055913 ! IL18R_HUMAN relationship: location_of CCO:B0055916 ! VPP3_HUMAN relationship: location_of CCO:B0055932 ! DGKZ_HUMAN relationship: location_of CCO:B0055934 ! OR2F1_HUMAN relationship: location_of CCO:B0055937 ! 5HT4R_HUMAN relationship: location_of CCO:B0055940 ! 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Q5VX04_HUMAN relationship: location_of CCO:B0056730 ! GP139_HUMAN relationship: location_of CCO:B0056760 ! OR5MA_HUMAN relationship: location_of CCO:B0056762 ! Q6IEV1_HUMAN relationship: location_of CCO:B0056763 ! Q6IEV3_HUMAN relationship: location_of CCO:B0056764 ! OR4CB_HUMAN relationship: location_of CCO:B0056765 ! Q6IEW7_HUMAN relationship: location_of CCO:B0056767 ! Q6IEX5_HUMAN relationship: location_of CCO:B0056768 ! OR4F3_HUMAN relationship: location_of CCO:B0056771 ! OR2T5_HUMAN relationship: location_of CCO:B0056772 ! OR2T2_HUMAN relationship: location_of CCO:B0056774 ! Q6IF12_HUMAN relationship: location_of CCO:B0056775 ! Q6IF17_HUMAN relationship: location_of CCO:B0056776 ! Q6IF36_HUMAN relationship: location_of CCO:B0056777 ! Q6IF40_HUMAN relationship: location_of CCO:B0056778 ! OR2A2_HUMAN relationship: location_of CCO:B0056779 ! Q6IF52_HUMAN relationship: location_of CCO:B0056780 ! O52W1_HUMAN relationship: location_of CCO:B0056781 ! Q6IF70_HUMAN relationship: location_of CCO:B0056782 ! Q6IF79_HUMAN relationship: location_of CCO:B0056783 ! O4A47_HUMAN relationship: location_of CCO:B0056784 ! O10K2_HUMAN relationship: location_of CCO:B0056785 ! Q6IFB0_HUMAN relationship: location_of CCO:B0056786 ! Q6IFD1_HUMAN relationship: location_of CCO:B0056787 ! Q6IFD3_HUMAN relationship: location_of CCO:B0056788 ! Q6IFD6_HUMAN relationship: location_of CCO:B0056790 ! Q6IFG3_HUMAN relationship: location_of CCO:B0056791 ! Q6IFG5_HUMAN relationship: location_of CCO:B0056792 ! Q6IFG6_HUMAN relationship: location_of CCO:B0056793 ! Q6IFG8_HUMAN relationship: location_of CCO:B0056794 ! OR6B2_HUMAN relationship: location_of CCO:B0056795 ! Q6IFH9_HUMAN relationship: location_of CCO:B0056796 ! Q6IFI0_HUMAN relationship: location_of CCO:B0056797 ! Q6IFI1_HUMAN relationship: location_of CCO:B0056798 ! Q6IFI5_HUMAN relationship: location_of CCO:B0056799 ! Q6IFI7_HUMAN relationship: location_of CCO:B0056801 ! Q6IFJ4_HUMAN relationship: location_of CCO:B0056802 ! Q6IFJ8_HUMAN relationship: location_of CCO:B0056803 ! Q6IFK7_HUMAN relationship: location_of CCO:B0056804 ! Q6IFK8_HUMAN relationship: location_of CCO:B0056805 ! Q6IFK9_HUMAN relationship: location_of CCO:B0056806 ! Q6IFL0_HUMAN relationship: location_of CCO:B0056807 ! Q6IFL1_HUMAN relationship: location_of CCO:B0056808 ! Q6IFL9_HUMAN relationship: location_of CCO:B0056809 ! Q6IFM6_HUMAN relationship: location_of CCO:B0056810 ! Q6IFM8_HUMAN relationship: location_of CCO:B0056811 ! Q6IFN2_HUMAN relationship: location_of CCO:B0056813 ! Q6IFP3_HUMAN relationship: location_of CCO:B0056814 ! Q6IFP9_HUMAN relationship: location_of CCO:B0056815 ! Q6IFR1_HUMAN relationship: location_of CCO:B0056818 ! Q6IFS1_HUMAN relationship: location_of CCO:B0056842 ! R7BP_HUMAN relationship: location_of CCO:B0056860 ! Q6NUP5_HUMAN relationship: location_of CCO:B0056862 ! GP153_HUMAN relationship: location_of CCO:B0056863 ! 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VN1R5_HUMAN relationship: location_of CCO:B0057182 ! VN1R4_HUMAN relationship: location_of CCO:B0057188 ! GP142_HUMAN relationship: location_of CCO:B0057189 ! GP141_HUMAN relationship: location_of CCO:B0057194 ! SPRE2_HUMAN relationship: location_of CCO:B0057199 ! RAB44_HUMAN relationship: location_of CCO:B0057220 ! GP144_HUMAN relationship: location_of CCO:B0057228 ! AMGO2_HUMAN relationship: location_of CCO:B0057229 ! MRGRG_HUMAN relationship: location_of CCO:B0057231 ! GP149_HUMAN relationship: location_of CCO:B0057232 ! EMR4_HUMAN relationship: location_of CCO:B0057233 ! GP123_HUMAN relationship: location_of CCO:B0057254 ! NOXA1_HUMAN relationship: location_of CCO:B0057293 ! TCAM2_HUMAN relationship: location_of CCO:B0057300 ! GPR97_HUMAN relationship: location_of CCO:B0057306 ! PDPN_HUMAN relationship: location_of CCO:B0057312 ! MIB1_HUMAN relationship: location_of CCO:B0057365 ! CNTN4_HUMAN relationship: location_of CCO:B0057370 ! Q8IXD9_HUMAN relationship: location_of CCO:B0057372 ! OR4N5_HUMAN relationship: location_of CCO:B0057373 ! Q8IXE4_HUMAN relationship: location_of CCO:B0057389 ! REM2_HUMAN relationship: location_of CCO:B0057402 ! GP116_HUMAN relationship: location_of CCO:B0057403 ! GP115_HUMAN relationship: location_of CCO:B0057404 ! GP114_HUMAN relationship: location_of CCO:B0057405 ! GP113_HUMAN relationship: location_of CCO:B0057406 ! GP111_HUMAN relationship: location_of CCO:B0057413 ! Q8N0W0_HUMAN relationship: location_of CCO:B0057414 ! Q8N0W1_HUMAN relationship: location_of CCO:B0057415 ! Q8N0X1_HUMAN relationship: location_of CCO:B0057417 ! OR4N4_HUMAN relationship: location_of CCO:B0057418 ! OR8I2_HUMAN relationship: location_of CCO:B0057419 ! ABRA_HUMAN relationship: location_of CCO:B0057424 ! Q8N164_HUMAN relationship: location_of CCO:B0057431 ! CRPAK_HUMAN relationship: location_of CCO:B0057433 ! RGNEF_HUMAN relationship: location_of CCO:B0057446 ! NLGN1_HUMAN relationship: location_of CCO:B0057453 ! OR2LD_HUMAN relationship: location_of CCO:B0057459 ! LIRB2_HUMAN relationship: location_of CCO:B0057483 ! OR2C3_HUMAN relationship: location_of CCO:B0057487 ! LIRA3_HUMAN relationship: location_of CCO:B0057494 ! GP161_HUMAN relationship: location_of CCO:B0057581 ! GPR26_HUMAN relationship: location_of CCO:B0057584 ! PSD4_HUMAN relationship: location_of CCO:B0057598 ! NOXO1_HUMAN relationship: location_of CCO:B0057604 ! PKR2_HUMAN relationship: location_of CCO:B0057606 ! GP156_HUMAN relationship: location_of CCO:B0057610 ! VN1R2_HUMAN relationship: location_of CCO:B0057615 ! Q8NG71_HUMAN relationship: location_of CCO:B0057616 ! Q8NG73_HUMAN relationship: location_of CCO:B0057617 ! O2T33_HUMAN relationship: location_of CCO:B0057618 ! O2T12_HUMAN relationship: location_of CCO:B0057619 ! OR2L5_HUMAN relationship: location_of CCO:B0057620 ! OR2M7_HUMAN relationship: location_of CCO:B0057621 ! OR2M3_HUMAN relationship: location_of CCO:B0057622 ! O2AK2_HUMAN relationship: location_of CCO:B0057623 ! OR2L3_HUMAN relationship: location_of CCO:B0057624 ! Q8NG91_HUMAN relationship: location_of CCO:B0057625 ! O13H1_HUMAN relationship: location_of CCO:B0057626 ! OR7G3_HUMAN relationship: location_of CCO:B0057627 ! OR2Z1_HUMAN relationship: location_of CCO:B0057628 ! OR7D4_HUMAN relationship: location_of CCO:B0057629 ! OR7G1_HUMAN relationship: location_of CCO:B0057630 ! OR1M1_HUMAN relationship: location_of CCO:B0057631 ! OR7A2_HUMAN relationship: location_of CCO:B0057634 ! O10H4_HUMAN relationship: location_of CCO:B0057635 ! O10H5_HUMAN relationship: location_of CCO:B0057636 ! O4F17_HUMAN relationship: location_of CCO:B0057637 ! Q8NGA9_HUMAN relationship: location_of CCO:B0057639 ! OR4C5_HUMAN relationship: location_of CCO:B0057640 ! OR4S1_HUMAN relationship: location_of CCO:B0057642 ! OR4M2_HUMAN relationship: location_of CCO:B0057643 ! O4F15_HUMAN relationship: location_of CCO:B0057644 ! OR4F6_HUMAN relationship: location_of CCO:B0057645 ! OR4E2_HUMAN relationship: location_of CCO:B0057646 ! O10G2_HUMAN relationship: location_of CCO:B0057647 ! O10G3_HUMAN relationship: location_of CCO:B0057648 ! OR6J1_HUMAN relationship: location_of CCO:B0057649 ! O11H6_HUMAN relationship: location_of CCO:B0057650 ! O11H7_HUMAN relationship: location_of CCO:B0057651 ! O11H4_HUMAN relationship: location_of CCO:B0057652 ! OR4M1_HUMAN relationship: location_of CCO:B0057653 ! OR4N2_HUMAN relationship: location_of CCO:B0057654 ! OR4K2_HUMAN relationship: location_of CCO:B0057655 ! OR4K5_HUMAN relationship: location_of CCO:B0057656 ! OR4K1_HUMAN relationship: location_of CCO:B0057657 ! OR4KE_HUMAN relationship: location_of CCO:B0057658 ! O10AD_HUMAN relationship: location_of CCO:B0057659 ! OR6C4_HUMAN relationship: location_of CCO:B0057660 ! O2AP1_HUMAN relationship: location_of CCO:B0057661 ! O10A7_HUMAN relationship: location_of CCO:B0057662 ! Q8NGE6_HUMAN relationship: location_of CCO:B0057663 ! OR4D9_HUMAN relationship: location_of CCO:B0057664 ! Q8NGF2_HUMAN relationship: location_of CCO:B0057665 ! O51D1_HUMAN relationship: location_of CCO:B0057666 ! O10W1_HUMAN relationship: location_of CCO:B0057667 ! OR4B1_HUMAN relationship: location_of CCO:B0057668 ! OR4X2_HUMAN relationship: location_of CCO:B0057669 ! OR8J3_HUMAN relationship: location_of CCO:B0057671 ! OR8K1_HUMAN relationship: location_of CCO:B0057672 ! OR8BC_HUMAN relationship: location_of CCO:B0057673 ! OR8B3_HUMAN relationship: location_of CCO:B0057674 ! Q8NGG9_HUMAN relationship: location_of CCO:B0057675 ! Q8NGH2_HUMAN relationship: location_of CCO:B0057676 ! O52E4_HUMAN relationship: location_of CCO:B0057677 ! O52N2_HUMAN relationship: location_of CCO:B0057678 ! O56B2_HUMAN relationship: location_of CCO:B0057679 ! O52N4_HUMAN relationship: location_of CCO:B0057680 ! 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C42S1_HUMAN relationship: location_of CCO:B0058909 ! GP173_HUMAN relationship: location_of CCO:B0058910 ! GPR27_HUMAN relationship: location_of CCO:B0058916 ! Q9NSC9_HUMAN relationship: location_of CCO:B0058918 ! RL3R1_HUMAN relationship: location_of CCO:B0058919 ! CISH_HUMAN relationship: location_of CCO:B0058931 ! RIC8B_HUMAN relationship: location_of CCO:B0058965 ! GPR83_HUMAN relationship: location_of CCO:B0058993 ! GPC5D_HUMAN relationship: location_of CCO:B0058996 ! GPC5B_HUMAN relationship: location_of CCO:B0059007 ! OR6C3_HUMAN relationship: location_of CCO:B0059008 ! OR6C2_HUMAN relationship: location_of CCO:B0059011 ! PD1L1_HUMAN relationship: location_of CCO:B0059029 ! VAPA_HUMAN relationship: location_of CCO:B0059038 ! TAAR3_HUMAN relationship: location_of CCO:B0059039 ! TAAR2_HUMAN relationship: location_of CCO:B0059040 ! OR1A1_HUMAN relationship: location_of CCO:B0059045 ! SIRPG_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059061 ! GBG13_HUMAN relationship: location_of CCO:B0059074 ! XPR1_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059120 ! O14J1_HUMAN relationship: location_of CCO:B0059121 ! OR5V1_HUMAN relationship: location_of CCO:B0059122 ! O12D3_HUMAN relationship: location_of CCO:B0059146 ! CLC2D_HUMAN relationship: location_of CCO:B0059149 ! Q9UHV4_HUMAN relationship: location_of CCO:B0059152 ! EMR2_HUMAN relationship: location_of CCO:B0059168 ! GP160_HUMAN relationship: location_of CCO:B0059182 ! GBG8_HUMAN relationship: location_of CCO:B0059195 ! O52A1_HUMAN relationship: location_of CCO:B0059199 ! UR2R_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059212 ! Q9UL14_HUMAN relationship: location_of CCO:B0059221 ! RAB23_HUMAN relationship: location_of CCO:B0059236 ! RAB26_HUMAN relationship: location_of CCO:B0059240 ! Q9UM77_HUMAN relationship: location_of CCO:B0059244 ! GUC1B_HUMAN relationship: location_of CCO:B0059250 ! EDAR_HUMAN relationship: location_of CCO:B0059259 ! GPR34_HUMAN relationship: location_of CCO:B0059276 ! CNTN6_HUMAN relationship: location_of CCO:B0059296 ! TN13B_HUMAN relationship: location_of CCO:B0059316 ! GPR52_HUMAN relationship: location_of CCO:B0059317 ! GPR55_HUMAN relationship: location_of CCO:B0059341 ! OR2W1_HUMAN relationship: location_of CCO:B0059356 ! O10H1_HUMAN relationship: location_of CCO:B0059359 ! PLXD1_HUMAN relationship: location_of CCO:B0059362 ! RPGF2_HUMAN relationship: location_of CCO:B0059374 ! OR1A2_HUMAN relationship: location_of CCO:B0059379 ! HRH3_HUMAN relationship: location_of CCO:B0059380 ! O51B4_HUMAN relationship: location_of CCO:B0059381 ! O51B2_HUMAN relationship: location_of CCO:B0059387 ! TNR18_HUMAN relationship: location_of CCO:B0059392 ! NPFF2_HUMAN relationship: location_of CCO:B0059393 ! GPR44_HUMAN relationship: location_of CCO:B0059397 ! GPR56_HUMAN relationship: location_of CCO:B0059423 ! LY96_HUMAN relationship: location_of CCO:B0062769 ! EXOC7_HUMAN relationship: location_of CCO:B0062791 ! NECP2_HUMAN relationship: location_of CCO:B0062812 ! DYL2_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062824 ! AP2M1_HUMAN relationship: location_of CCO:B0062852 ! KELL_HUMAN relationship: location_of CCO:B0062858 ! SNP23_HUMAN relationship: location_of CCO:B0062866 ! CD177_HUMAN relationship: location_of CCO:B0062873 ! LIMS1_HUMAN relationship: location_of CCO:B0062896 ! ZMY19_HUMAN relationship: location_of CCO:B0062929 ! MALL_HUMAN relationship: location_of CCO:B0062941 ! NTNG2_HUMAN relationship: location_of CCO:B0062981 ! LAIR1_HUMAN relationship: location_of CCO:B0062984 ! LEG4_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063007 ! ANTR2_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063146 ! I10R1_HUMAN relationship: location_of CCO:B0063197 ! MUC13_HUMAN relationship: location_of CCO:B0063205 ! TACD1_HUMAN relationship: location_of CCO:B0063213 ! HCD2_HUMAN relationship: location_of CCO:B0063222 ! OSTA_HUMAN relationship: location_of CCO:B0063227 ! MEP1B_HUMAN relationship: location_of CCO:B0063229 ! SCRB1_HUMAN relationship: location_of CCO:B0063239 ! ICAM3_HUMAN relationship: location_of CCO:B0063248 ! HA25_HUMAN relationship: location_of CCO:B0063249 ! HB25_HUMAN relationship: location_of CCO:B0063267 ! ACCN1_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063273 ! GHR_HUMAN relationship: location_of CCO:B0063286 ! LEG3_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0063303 ! VPP2_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063334 ! ERG25_HUMAN relationship: location_of CCO:B0063336 ! SIA7F_HUMAN relationship: location_of CCO:B0063340 ! 2DRA_HUMAN relationship: location_of CCO:B0063349 ! PTN4_HUMAN relationship: location_of CCO:B0063391 ! UBE2B_HUMAN relationship: location_of CCO:B0063442 ! TUTLA_HUMAN relationship: location_of CCO:B0063443 ! LIPL_HUMAN relationship: location_of CCO:B0063454 ! CD48_HUMAN relationship: location_of CCO:B0063491 ! SPRN_HUMAN relationship: location_of CCO:B0063507 ! LY6H_HUMAN relationship: location_of CCO:B0063615 ! ARRB1_HUMAN-Phosphothreonine410 relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: location_of CCO:B0063708 ! BAI3_HUMAN-Phosphoserine1220 relationship: location_of CCO:B0063711 ! BAIP2_HUMAN-Phosphothreonine296 relationship: location_of CCO:B0063733 ! BASI_HUMAN-Phosphoserine362 relationship: location_of CCO:B0063924 ! BIM_HUMAN-Phosphoserine77 relationship: location_of CCO:B0063980 ! BRAF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064022 ! C3AR_HUMAN-Sulfotyrosine174 relationship: location_of CCO:B0064025 ! C5ARL_HUMAN-Phosphoserine326 relationship: location_of CCO:B0064030 ! C5AR_HUMAN-Phosphoserine327 relationship: location_of CCO:B0064043 ! CAC1D_HUMAN-Phosphoserine1475 relationship: location_of CCO:B0064059 ! CAP1_HUMAN-Phosphoserine290 relationship: location_of CCO:B0064067 ! CAR14_HUMAN-Phosphoserine544 relationship: location_of CCO:B0064121 ! CCR10_HUMAN-Phosphothreonine295 relationship: location_of CCO:B0064123 ! CCR2_HUMAN-Sulfotyrosine26 relationship: location_of CCO:B0064135 ! CD19_HUMAN-Phosphotyrosine378 relationship: location_of CCO:B0064151 ! CD33_HUMAN-Phosphotyrosine340 relationship: location_of CCO:B0064154 ! CD3D_HUMAN-Phosphotyrosine160 relationship: location_of CCO:B0064160 ! CD3G_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0064164 ! CD3Z_HUMAN-Phosphotyrosine83 relationship: location_of CCO:B0064171 ! CD5_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0064255 ! CELR1_HUMAN-Phosphoserine2761 relationship: location_of CCO:B0064358 ! CIP4_HUMAN-Phosphoserine335 relationship: location_of CCO:B0064416 ! CNKR1_HUMAN-Phosphoserine305 relationship: location_of CCO:B0064467 ! CRIM1_HUMAN-Phosphothreonine1035 relationship: location_of CCO:B0064473 ! CRK_HUMAN-Phosphoserine41 relationship: location_of CCO:B0064552 ! CSF1R_HUMAN-Phosphothreonine562 relationship: location_of CCO:B0064587 ! CTNL1_HUMAN-Phosphoserine538 relationship: location_of CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: location_of CCO:B0064689 ! DDEF2_HUMAN-Phosphoserine701 relationship: location_of CCO:B0064751 ! DGKA_HUMAN-Phosphotyrosine22 relationship: location_of CCO:B0064792 ! DNER_HUMAN-Phosphotyrosine718 relationship: location_of CCO:B0065098 ! EPOR_HUMAN-Phosphotyrosine504 relationship: location_of CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 relationship: location_of CCO:B0065165 ! ETBR2_HUMAN-Phosphoserine471 relationship: location_of CCO:B0065229 ! AA3R_HUMAN-Phosphoserine317 relationship: location_of CCO:B0065314 ! ACCN3_HUMAN-Phosphoserine521 relationship: location_of CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: location_of CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: location_of CCO:B0065404 ! ADCY5_HUMAN-Phosphoserine8 relationship: location_of CCO:B0065410 ! ADCYA_HUMAN-Phosphothreonine809 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: location_of CCO:B0065764 ! ATPO_HUMAN-N6-acetyllysine176 relationship: location_of CCO:B0065801 ! C1QBP_HUMAN-Phosphoserine201 relationship: location_of CCO:B0065810 ! CAD10_HUMAN-Phosphoserine784 relationship: location_of CCO:B0065817 ! CALY_HUMAN-Phosphotyrosine151 relationship: location_of CCO:B0065843 ! CD22_HUMAN-Phosphotyrosine762 relationship: location_of CCO:B0065880 ! CLD12_HUMAN-Phosphoserine228 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: location_of CCO:B0065965 ! E41L3_HUMAN-Phosphothreonine703 relationship: location_of CCO:B0066008 ! ENOX1_HUMAN-Phosphoserine403 relationship: location_of CCO:B0066010 ! EPN1_HUMAN-Phosphoserine395 relationship: location_of CCO:B0066072 ! FA10_HUMAN-4-carboxyglutamate79 relationship: location_of CCO:B0066109 ! FA7_HUMAN-4-carboxyglutamate85 relationship: location_of CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: location_of CCO:B0066149 ! FCERG_HUMAN-Phosphotyrosine76 relationship: location_of CCO:B0066152 ! FCGR1_HUMAN-Phosphotyrosine138 relationship: location_of CCO:B0066173 ! FFAR1_HUMAN-Phosphotyrosine44 relationship: location_of CCO:B0066189 ! FIBA_HUMAN-Phosphoserine364 relationship: location_of CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0066324 ! FYN_HUMAN-Phosphotyrosine213 relationship: location_of CCO:B0066399 ! GBG12_HUMAN-Phosphotyrosine42 relationship: location_of CCO:B0066401 ! GBG2_HUMAN-Phosphothreonine52 relationship: location_of CCO:B0066484 ! GNA15_HUMAN-ADP-ribosylarginine186 relationship: location_of CCO:B0066489 ! GNAS1_HUMAN-ADP-ribosylarginine844 relationship: location_of CCO:B0066490 ! GNAS2_HUMAN-Phosphoserine51 relationship: location_of CCO:B0066524 ! GP125_HUMAN-Phosphothreonine208 relationship: location_of CCO:B0066526 ! GP126_HUMAN-Phosphoserine1165 relationship: location_of CCO:B0066536 ! GP1BB_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 relationship: location_of CCO:B0066544 ! GPR12_HUMAN-Phosphoserine332 relationship: location_of CCO:B0066549 ! GPR6_HUMAN-Phosphoserine356 relationship: location_of CCO:B0066579 ! GRB10_HUMAN-Phosphoserine150 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066606 ! GRIA2_HUMAN-Phosphoserine880 relationship: location_of CCO:B0066608 ! GRIA3_HUMAN-Phosphotyrosine887 relationship: location_of CCO:B0066627 ! GRM1_HUMAN-Phosphotyrosine1109 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0066895 ! HRH1_HUMAN-Phosphoserine275 relationship: location_of CCO:B0067002 ! ICLN_HUMAN-Phosphoserine102 relationship: location_of CCO:B0067079 ! IL4RA_HUMAN-Phosphotyrosine631 relationship: location_of CCO:B0067115 ! INGR2_HUMAN-Phosphoserine198 relationship: location_of CCO:B0067163 ! ITK_HUMAN-Phosphoserine565 relationship: location_of CCO:B0067170 ! ITPR2_HUMAN-Phosphotyrosine2607 relationship: location_of CCO:B0067173 ! ITPR3_HUMAN-Phosphoserine1832 relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: location_of CCO:B0067285 ! KCIP2_HUMAN-Phosphotyrosine111 relationship: location_of CCO:B0067505 ! KSYK_HUMAN-Phosphotyrosine323 relationship: location_of CCO:B0067581 ! LAT_HUMAN-Phosphoserine84 relationship: location_of CCO:B0067594 ! LAX1_HUMAN-Phosphotyrosine373 relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: location_of CCO:B0067643 ! LGR6_HUMAN-Phosphoserine457 relationship: location_of CCO:B0067765 ! LPHN1_HUMAN-Phosphoserine1377 relationship: location_of CCO:B0067770 ! LPHN3_HUMAN-Phosphothreonine1445 relationship: location_of CCO:B0067794 ! LTK_HUMAN-Phosphotyrosine672 relationship: location_of CCO:B0067845 ! MADD_HUMAN-Phosphoserine921 relationship: location_of CCO:B0067849 ! MAGD1_HUMAN-Phosphotyrosine92 relationship: location_of CCO:B0067856 ! MAGI2_HUMAN-Phosphotyrosine827 relationship: location_of CCO:B0067998 ! MAST2_HUMAN-Phosphoserine74 relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068447 ! NBEA_HUMAN-Phosphoserine1529 relationship: location_of CCO:B0068532 ! NDRG1_HUMAN-Phosphoserine330 relationship: location_of CCO:B0068580 ! NEUM_HUMAN-Phosphoserine41 relationship: location_of CCO:B0068634 ! NFAM1_HUMAN-Phosphotyrosine231 relationship: location_of CCO:B0068715 ! NHRF2_HUMAN-Phosphoserine183 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0068796 ! NOSTN_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0068815 ! NPHN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0068836 ! NRG3_HUMAN-Phosphoserine119 relationship: location_of CCO:B0068876 ! NTAL_HUMAN-Phosphotyrosine233 relationship: location_of CCO:B0068879 ! NTRK1_HUMAN-Phosphotyrosine680 relationship: location_of CCO:B0068951 ! O52E8_HUMAN-Phosphoserine144 relationship: location_of CCO:B0068952 ! O56A3_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0068975 ! OPSD_HUMAN-Phosphoserine343 relationship: location_of CCO:B0068982 ! OR4S2_HUMAN-Phosphoserine227 relationship: location_of CCO:B0069007 ! OX1R_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0069016 ! P2RX7_HUMAN-Phosphotyrosine343 relationship: location_of CCO:B0069018 ! P2RY1_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069020 ! P2RY4_HUMAN-Phosphoserine334 relationship: location_of CCO:B0069049 ! PACN3_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069056 ! PAG1_HUMAN-Phosphotyrosine227 relationship: location_of CCO:B0069078 ! PALM2_HUMAN-Phosphoserine318 relationship: location_of CCO:B0069088 ! PALM_HUMAN-Phosphothreonine158 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0069184 ! PDE6A_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 relationship: location_of CCO:B0069291 ! PI2R_HUMAN-Cysteine methyl ester383 relationship: location_of CCO:B0069292 ! PI42B_HUMAN-Phosphotyrosine98 relationship: location_of CCO:B0069380 ! PKP2_HUMAN-Phosphoserine329 relationship: location_of CCO:B0069394 ! PLCG2_HUMAN-Phosphotyrosine733 relationship: location_of CCO:B0069399 ! PLCH2_HUMAN-Phosphoserine605 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069640 ! PVRL2_HUMAN-Phosphoserine433 relationship: location_of CCO:B0069665 ! RAB13_HUMAN-Phosphoserine178 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0069670 ! RAB15_HUMAN-Cysteine methyl ester212 relationship: location_of CCO:B0069671 ! RAB18_HUMAN-Phosphothreonine29 relationship: location_of CCO:B0069680 ! RAB3A_HUMAN-Phosphoserine188 relationship: location_of CCO:B0069683 ! RAB3B_HUMAN-Cysteine methyl ester219 relationship: location_of CCO:B0069688 ! RAB43_HUMAN-Cysteine methyl ester212 relationship: location_of CCO:B0069720 ! RAI3_HUMAN-Phosphotyrosine347 relationship: location_of CCO:B0069748 ! RASA3_HUMAN-Phosphoserine809 relationship: location_of CCO:B0069749 ! RASD1_HUMAN-S-nitrosocysteine11 relationship: location_of CCO:B0069760 ! RB39A_HUMAN-Cysteine methyl ester217 relationship: location_of CCO:B0069761 ! RB39B_HUMAN-Cysteine methyl ester213 relationship: location_of CCO:B0069921 ! RGRF2_HUMAN-Phosphoserine737 relationship: location_of CCO:B0069929 ! RHG01_HUMAN-Phosphotyrosine65 relationship: location_of CCO:B0070012 ! RHOH_HUMAN-Cysteine methyl ester188 relationship: location_of CCO:B0070013 ! RHOJ_HUMAN-Cysteine methyl ester211 relationship: location_of CCO:B0070014 ! RHOQ_HUMAN-Cysteine methyl ester202 relationship: location_of CCO:B0070161 ! RPE65_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070172 ! RPGF6_HUMAN-Phosphothreonine1507 relationship: location_of CCO:B0070249 ! RSLAB_HUMAN-Cysteine methyl ester200 relationship: location_of CCO:B0070272 ! RYR2_HUMAN-Phosphoserine2806 relationship: location_of CCO:B0070287 ! S38A3_HUMAN-Phosphoserine54 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070377 ! SERC3_HUMAN-Phosphoserine371 relationship: location_of CCO:B0070469 ! SH2B2_HUMAN-Phosphotyrosine629 relationship: location_of CCO:B0070494 ! SHB_HUMAN-Phosphoserine314 relationship: location_of CCO:B0070510 ! SHPS1_HUMAN-Phosphotyrosine495 relationship: location_of CCO:B0070556 ! SIT1_HUMAN-Phosphotyrosine127 relationship: location_of CCO:B0070565 ! SKAP1_HUMAN-Phosphotyrosine142 relationship: location_of CCO:B0070574 ! SKAP2_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0070575 ! SLAF1_HUMAN-Phosphotyrosine281 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0070904 ! SRC_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0071331 ! TENC1_HUMAN-Phosphoserine835 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071584 ! TRPC6_HUMAN-Phosphoserine815 relationship: location_of CCO:B0071732 ! UN13A_HUMAN-Phosphoserine245 relationship: location_of CCO:B0071733 ! UN13B_HUMAN-Phosphothreonine605 relationship: location_of CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 relationship: location_of CCO:B0071789 ! VAV2_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0071808 ! VIPR1_HUMAN-Phosphoserine449 relationship: location_of CCO:B0072275 ! ZO3_HUMAN-Phosphoserine579 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000445 name: integral to plasma membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:go_curators] subset: gosubset_prok xref: GO:0005887 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001150 ! intrinsic to plasma membrane relationship: location_of CCO:B0001362 ! EREG_HUMAN relationship: location_of CCO:B0001406 ! ADCY3_HUMAN relationship: location_of CCO:B0001448 ! TNF15_HUMAN relationship: location_of CCO:B0001557 ! PAR1_HUMAN relationship: location_of CCO:B0001591 ! PHB_HUMAN relationship: location_of CCO:B0001719 ! NOTC2_HUMAN relationship: location_of CCO:B0001765 ! PTC1_HUMAN relationship: location_of CCO:B0001767 ! BMPR2_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0002245 ! JAG2_HUMAN relationship: location_of CCO:B0005325 ! IL1R1_HUMAN relationship: location_of CCO:B0005445 ! SDC2_HUMAN relationship: location_of CCO:B0005450 ! ICAM1_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005534 ! TNR1A_HUMAN relationship: location_of CCO:B0005543 ! AVR2A_HUMAN relationship: location_of CCO:B0005545 ! NRX1A_HUMAN relationship: location_of CCO:B0005618 ! TRBM_HUMAN relationship: location_of CCO:B0005628 ! ALK_HUMAN relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0005707 ! TNR14_HUMAN relationship: location_of CCO:B0005723 ! MTR1A_HUMAN relationship: location_of CCO:B0005724 ! MTR1B_HUMAN relationship: location_of CCO:B0005760 ! NEP_HUMAN relationship: location_of CCO:B0005868 ! FGFR1_HUMAN relationship: location_of CCO:B0005906 ! ERBB4_HUMAN relationship: location_of CCO:B0005981 ! TRI27_HUMAN relationship: location_of CCO:B0006099 ! PCDA4_HUMAN relationship: location_of CCO:B0006104 ! PTPRS_HUMAN relationship: location_of CCO:B0006207 ! MPP3_HUMAN relationship: location_of CCO:B0006262 ! CD81_HUMAN relationship: location_of CCO:B0006269 ! EFNA1_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0006331 ! GOLM1_HUMAN relationship: location_of CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: location_of CCO:B0010450 ! ACV1B_HUMAN-Phosphotyrosine380 relationship: location_of CCO:B0010454 ! ADA17_HUMAN-Phosphoserine382 relationship: location_of CCO:B0010459 ! ADAM9_HUMAN-Phosphothreonine761 relationship: location_of CCO:B0010462 ! ADT2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011014 ! CD28_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0011050 ! CD45_HUMAN-Phosphoserine1003 relationship: location_of CCO:B0011460 ! DDR1_HUMAN-Phosphotyrosine792 relationship: location_of CCO:B0011722 ! EPHA2_HUMAN-Phosphotyrosine594 relationship: location_of CCO:B0011734 ! EPHB4_HUMAN-Phosphotyrosine590 relationship: location_of CCO:B0012337 ! IGF1R_HUMAN-Phosphotyrosine1161 relationship: location_of CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: location_of CCO:B0012714 ! M2OM_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012916 ! MET_HUMAN-Phosphotyrosine1356 relationship: location_of CCO:B0012980 ! MPCP_HUMAN-N6-acetyllysine99 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014576 ! UFO_HUMAN-Phosphotyrosine696 relationship: location_of CCO:B0014615 ! VGFR1_HUMAN-Phosphotyrosine1213 relationship: location_of CCO:B0015136 ! SCTR_HUMAN relationship: location_of CCO:B0015164 ! HHIP_HUMAN relationship: location_of CCO:B0015778 ! PILRB_HUMAN relationship: location_of CCO:B0016682 ! GUC2D_HUMAN relationship: location_of CCO:B0016684 ! GUC2F_HUMAN relationship: location_of CCO:B0018438 ! CCRL1_HUMAN relationship: location_of CCO:B0018486 ! CLTR1_HUMAN relationship: location_of CCO:B0018655 ! RYK_HUMAN relationship: location_of CCO:B0018695 ! EDNRA_HUMAN relationship: location_of CCO:B0018697 ! EDNRB_HUMAN relationship: location_of CCO:B0019141 ! ASGR1_HUMAN relationship: location_of CCO:B0020366 ! ACVL1_HUMAN relationship: location_of CCO:B0020371 ! BMR1B_HUMAN relationship: location_of CCO:B0020605 ! GRIK3_HUMAN relationship: location_of CCO:B0020611 ! GRIK2_HUMAN relationship: location_of CCO:B0020614 ! GRIK1_HUMAN relationship: location_of CCO:B0020617 ! GRIK4_HUMAN relationship: location_of CCO:B0020879 ! ADCY7_HUMAN relationship: location_of CCO:B0021417 ! CALRL_HUMAN relationship: location_of CCO:B0021671 ! HBEGF_HUMAN relationship: location_of CCO:B0021887 ! I17RB_HUMAN relationship: location_of CCO:B0022071 ! TLR4_HUMAN relationship: location_of CCO:B0022899 ! GBRR2_HUMAN relationship: location_of CCO:B0022901 ! GBRE_HUMAN relationship: location_of CCO:B0022903 ! GBRT_HUMAN relationship: location_of CCO:B0022907 ! GBRA6_HUMAN relationship: location_of CCO:B0022909 ! GBRG2_HUMAN relationship: location_of CCO:B0022911 ! GLRB_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022914 ! GBRA1_HUMAN relationship: location_of CCO:B0022915 ! GBRA5_HUMAN relationship: location_of CCO:B0022917 ! GLRA2_HUMAN relationship: location_of CCO:B0022926 ! GBRR1_HUMAN relationship: location_of CCO:B0022931 ! GBRD_HUMAN relationship: location_of CCO:B0022933 ! GBRA3_HUMAN relationship: location_of CCO:B0022999 ! PTPRK_HUMAN relationship: location_of CCO:B0023006 ! PTPRT_HUMAN relationship: location_of CCO:B0023019 ! PTPRU_HUMAN relationship: location_of CCO:B0023521 ! CD2_HUMAN relationship: location_of CCO:B0024306 ! PSYR_HUMAN relationship: location_of CCO:B0024308 ! GPR4_HUMAN relationship: location_of CCO:B0025098 ! LETM1_HUMAN relationship: location_of CCO:B0025167 ! TRPC5_HUMAN relationship: location_of CCO:B0025169 ! TRPC1_HUMAN relationship: location_of CCO:B0025184 ! IL6RB_HUMAN relationship: location_of CCO:B0025847 ! PTPRN_HUMAN relationship: location_of CCO:B0026166 ! LANC1_HUMAN relationship: location_of CCO:B0026215 ! ITA2B_HUMAN relationship: location_of CCO:B0026218 ! ITAV_HUMAN relationship: location_of CCO:B0028201 ! OR1D2_HUMAN relationship: location_of CCO:B0028290 ! JAG1_HUMAN relationship: location_of CCO:B0028292 ! DLL1_HUMAN relationship: location_of CCO:B0029727 ! CEAM1_HUMAN relationship: location_of CCO:B0030164 ! TLR1_HUMAN relationship: location_of CCO:B0030171 ! TLR2_HUMAN relationship: location_of CCO:B0030172 ! TLR6_HUMAN relationship: location_of CCO:B0030552 ! MC3R_HUMAN relationship: location_of CCO:B0030561 ! MSHR_HUMAN relationship: location_of CCO:B0030569 ! MC5R_HUMAN relationship: location_of CCO:B0030577 ! ACTHR_HUMAN relationship: location_of CCO:B0030613 ! DCLK1_HUMAN relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: location_of CCO:B0030995 ! IRK2_HUMAN relationship: location_of CCO:B0031317 ! FGFR3_HUMAN-Phosphotyrosine647 relationship: location_of CCO:B0032298 ! I17RA_HUMAN relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0033141 ! ITB3_HUMAN relationship: location_of CCO:B0033252 ! OPSX_HUMAN relationship: location_of CCO:B0033418 ! GPR64_HUMAN relationship: location_of CCO:B0034159 ! AQP1_HUMAN relationship: location_of CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0034546 ! ANPRA_HUMAN-Phosphoserine534 relationship: location_of CCO:B0034728 ! EPHA1_HUMAN-Phosphoserine34 relationship: location_of CCO:B0034734 ! EPHA3_HUMAN-Phosphotyrosine596 relationship: location_of CCO:B0034739 ! EPHA4_HUMAN-Phosphotyrosine602 relationship: location_of CCO:B0034756 ! EPHB1_HUMAN-Phosphotyrosine594 relationship: location_of CCO:B0034788 ! FCERB_HUMAN-Phosphotyrosine229 relationship: location_of CCO:B0034864 ! I12R2_HUMAN-Phosphotyrosine800 relationship: location_of CCO:B0034872 ! IL3RB_HUMAN-Phosphotyrosine766 relationship: location_of CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035307 ! NRCAM_HUMAN-Phosphoserine427 relationship: location_of CCO:B0035985 ! ACVR1_HUMAN-Phosphoserine501 relationship: location_of CCO:B0036594 ! NKG2C_HUMAN relationship: location_of CCO:B0036600 ! NKG2A_HUMAN relationship: location_of CCO:B0037229 ! PE2R3_HUMAN relationship: location_of CCO:B0038262 ! HRH2_HUMAN relationship: location_of CCO:B0038263 ! ADA1B_HUMAN relationship: location_of CCO:B0038265 ! ADA1D_HUMAN relationship: location_of CCO:B0038266 ! 5HT1D_HUMAN relationship: location_of CCO:B0038267 ! ADA2B_HUMAN relationship: location_of CCO:B0038854 ! FZD5_HUMAN relationship: location_of CCO:B0038857 ! FZD2_HUMAN relationship: location_of CCO:B0038865 ! FZD10_HUMAN relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0039298 ! ADA1A_HUMAN-Phosphoserine215 relationship: location_of CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: location_of CCO:B0039581 ! PGFRA_HUMAN-Phosphotyrosine720 relationship: location_of CCO:B0039677 ! TGFR1_HUMAN-Phosphoserine191 relationship: location_of CCO:B0039687 ! TRPV1_HUMAN-Phosphoserine775 relationship: location_of CCO:B0039914 ! TR13B_HUMAN relationship: location_of CCO:B0042222 ! GRM3_HUMAN relationship: location_of CCO:B0042225 ! GRM4_HUMAN relationship: location_of CCO:B0042227 ! GRM7_HUMAN relationship: location_of CCO:B0042230 ! GRM5_HUMAN relationship: location_of CCO:B0042239 ! GRM2_HUMAN relationship: location_of CCO:B0042241 ! GRM8_HUMAN relationship: location_of CCO:B0042244 ! GRM6_HUMAN relationship: location_of CCO:B0042293 ! ACHG_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0042813 ! IL2RB_HUMAN relationship: location_of CCO:B0042830 ! FCERA_HUMAN relationship: location_of CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 relationship: location_of CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0043866 ! LPAR2_HUMAN relationship: location_of CCO:B0043867 ! LPAR4_HUMAN relationship: location_of CCO:B0048252 ! EFNB1_HUMAN-Phosphotyrosine317 relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0049157 ! PAR4_HUMAN relationship: location_of CCO:B0049161 ! PAR2_HUMAN relationship: location_of CCO:B0049452 ! NK2R_HUMAN relationship: location_of CCO:B0049455 ! NK3R_HUMAN relationship: location_of CCO:B0049457 ! NK1R_HUMAN relationship: location_of CCO:B0049915 ! RAMP3_HUMAN relationship: location_of CCO:B0050006 ! CD72_HUMAN relationship: location_of CCO:B0050753 ! OPRD_HUMAN relationship: location_of CCO:B0050755 ! SSR2_HUMAN relationship: location_of CCO:B0050758 ! OPRK_HUMAN relationship: location_of CCO:B0050781 ! OPRX_HUMAN relationship: location_of CCO:B0050788 ! SSR1_HUMAN relationship: location_of CCO:B0050793 ! SSR4_HUMAN relationship: location_of CCO:B0050794 ! SSR3_HUMAN relationship: location_of CCO:B0051232 ! CLPT1_HUMAN relationship: location_of CCO:B0051475 ! MOT3_HUMAN relationship: location_of CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0052321 ! CEAM6_HUMAN-Phosphoserine243 relationship: location_of CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 relationship: location_of CCO:B0052794 ! SSR5_HUMAN-Phosphoserine325 relationship: location_of CCO:B0054291 ! GPR25_HUMAN relationship: location_of CCO:B0054302 ! SIRB1_HUMAN relationship: location_of CCO:B0054306 ! GPR31_HUMAN relationship: location_of CCO:B0054318 ! CCRL2_HUMAN relationship: location_of CCO:B0054333 ! CXCR6_HUMAN relationship: location_of CCO:B0054335 ! CCBP2_HUMAN relationship: location_of CCO:B0054336 ! PODXL_HUMAN relationship: location_of CCO:B0054344 ! LPP1_HUMAN relationship: location_of CCO:B0054348 ! BAI1_HUMAN relationship: location_of CCO:B0054375 ! TNF11_HUMAN relationship: location_of CCO:B0054378 ! TAAR5_HUMAN relationship: location_of CCO:B0054383 ! FFAR3_HUMAN relationship: location_of CCO:B0054432 ! GPR37_HUMAN relationship: location_of CCO:B0054444 ! GPR42_HUMAN relationship: location_of CCO:B0054448 ! FFAR2_HUMAN relationship: location_of CCO:B0054451 ! PLXB1_HUMAN relationship: location_of CCO:B0054459 ! MTLR_HUMAN relationship: location_of CCO:B0054460 ! GPR39_HUMAN relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0054484 ! TNF12_HUMAN relationship: location_of CCO:B0054485 ! AT8B1_HUMAN relationship: location_of CCO:B0054503 ! OX2R_HUMAN relationship: location_of CCO:B0054529 ! O43898_HUMAN relationship: location_of CCO:B0054549 ! FZD6_HUMAN relationship: location_of CCO:B0054587 ! RAMP1_HUMAN relationship: location_of CCO:B0054589 ! NSMA_HUMAN relationship: location_of CCO:B0054630 ! GPR32_HUMAN relationship: location_of CCO:B0054640 ! LGR5_HUMAN relationship: location_of CCO:B0054643 ! GPC4_HUMAN relationship: location_of CCO:B0054666 ! RHBL1_HUMAN relationship: location_of CCO:B0054688 ! NCTR1_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054748 ! MPZL1_HUMAN relationship: location_of CCO:B0054780 ! NTR2_HUMAN relationship: location_of CCO:B0054781 ! ECEL1_HUMAN relationship: location_of CCO:B0054794 ! GPR75_HUMAN relationship: location_of CCO:B0054807 ! NCTR2_HUMAN relationship: location_of CCO:B0054812 ! IGSF6_HUMAN relationship: location_of CCO:B0054813 ! S1PR4_HUMAN relationship: location_of CCO:B0054856 ! CD8A_HUMAN relationship: location_of CCO:B0054858 ! 2B32_HUMAN relationship: location_of CCO:B0054870 ! CO9_HUMAN relationship: location_of CCO:B0054879 ! OPSB_HUMAN relationship: location_of CCO:B0054880 ! OPSR_HUMAN relationship: location_of CCO:B0054881 ! OPSG_HUMAN relationship: location_of CCO:B0054888 ! MAS_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054916 ! CD3E_HUMAN relationship: location_of CCO:B0054921 ! TNR16_HUMAN relationship: location_of CCO:B0054929 ! ADRB1_HUMAN relationship: location_of CCO:B0054933 ! IL6RA_HUMAN relationship: location_of CCO:B0054934 ! 5HT1A_HUMAN relationship: location_of CCO:B0054937 ! ADA2A_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0054950 ! TACD2_HUMAN relationship: location_of CCO:B0054975 ! PTPRF_HUMAN relationship: location_of CCO:B0054983 ! CD8B_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0054995 ! CD20_HUMAN relationship: location_of CCO:B0055019 ! 2B14_HUMAN relationship: location_of CCO:B0055020 ! ADRB3_HUMAN relationship: location_of CCO:B0055024 ! DRD2_HUMAN relationship: location_of CCO:B0055047 ! LEUK_HUMAN relationship: location_of CCO:B0055054 ! TSHR_HUMAN relationship: location_of CCO:B0055084 ! TMM11_HUMAN relationship: location_of CCO:B0055092 ! EGLN_HUMAN relationship: location_of CCO:B0055104 ! ADA2C_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055131 ! MAL_HUMAN relationship: location_of CCO:B0055133 ! CNR1_HUMAN relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0055138 ! TA2R_HUMAN relationship: location_of CCO:B0055139 ! DRD4_HUMAN relationship: location_of CCO:B0055140 ! DRD5_HUMAN relationship: location_of CCO:B0055147 ! FGFR4_HUMAN relationship: location_of CCO:B0055152 ! LSHR_HUMAN relationship: location_of CCO:B0055157 ! PTPRD_HUMAN relationship: location_of CCO:B0055158 ! PTPRG_HUMAN relationship: location_of CCO:B0055160 ! TNFL4_HUMAN relationship: location_of CCO:B0055181 ! PTAFR_HUMAN relationship: location_of CCO:B0055187 ! NPY1R_HUMAN relationship: location_of CCO:B0055188 ! TNR5_HUMAN relationship: location_of CCO:B0055192 ! NKG2D_HUMAN relationship: location_of CCO:B0055193 ! CD27_HUMAN relationship: location_of CCO:B0055197 ! 5HT1B_HUMAN relationship: location_of CCO:B0055198 ! 5HT2A_HUMAN relationship: location_of CCO:B0055201 ! NMBR_HUMAN relationship: location_of CCO:B0055205 ! 5HT1E_HUMAN relationship: location_of CCO:B0055210 ! AA2AR_HUMAN relationship: location_of CCO:B0055211 ! AA2BR_HUMAN relationship: location_of CCO:B0055218 ! BKRB2_HUMAN relationship: location_of CCO:B0055219 ! V2R_HUMAN relationship: location_of CCO:B0055221 ! AA1R_HUMAN relationship: location_of CCO:B0055222 ! GRPR_HUMAN relationship: location_of CCO:B0055223 ! AGTR1_HUMAN relationship: location_of CCO:B0055224 ! OXYR_HUMAN relationship: location_of CCO:B0055226 ! 5HT1F_HUMAN relationship: location_of CCO:B0055228 ! O10J1_HUMAN relationship: location_of CCO:B0055229 ! GNRHR_HUMAN relationship: location_of CCO:B0055230 ! CALCR_HUMAN relationship: location_of CCO:B0055231 ! NTR1_HUMAN relationship: location_of CCO:B0055251 ! CCKAR_HUMAN relationship: location_of CCO:B0055252 ! GASR_HUMAN relationship: location_of CCO:B0055256 ! CCR1_HUMAN relationship: location_of CCO:B0055258 ! CCR7_HUMAN relationship: location_of CCO:B0055260 ! CXCR5_HUMAN relationship: location_of CCO:B0055262 ! CD70_HUMAN relationship: location_of CCO:B0055263 ! TNFL8_HUMAN relationship: location_of CCO:B0055272 ! 5HT7R_HUMAN relationship: location_of CCO:B0055273 ! CNR2_HUMAN relationship: location_of CCO:B0055274 ! TRFR_HUMAN relationship: location_of CCO:B0055275 ! PE2R1_HUMAN relationship: location_of CCO:B0055276 ! CRFR1_HUMAN relationship: location_of CCO:B0055290 ! APJ_HUMAN relationship: location_of CCO:B0055293 ! DRD3_HUMAN relationship: location_of CCO:B0055295 ! TIE1_HUMAN relationship: location_of CCO:B0055304 ! VGFR3_HUMAN relationship: location_of CCO:B0055305 ! VGFR2_HUMAN relationship: location_of CCO:B0055318 ! V1AR_HUMAN relationship: location_of CCO:B0055327 ! TPOR_HUMAN relationship: location_of CCO:B0055328 ! CD79B_HUMAN relationship: location_of CCO:B0055332 ! IL15_HUMAN relationship: location_of CCO:B0055335 ! CASR_HUMAN relationship: location_of CCO:B0055338 ! P2RY2_HUMAN relationship: location_of CCO:B0055341 ! PACR_HUMAN relationship: location_of CCO:B0055342 ! VIPR2_HUMAN relationship: location_of CCO:B0055343 ! 5HT2B_HUMAN relationship: location_of CCO:B0055354 ! I12R1_HUMAN relationship: location_of CCO:B0055355 ! LIFR_HUMAN relationship: location_of CCO:B0055358 ! PF2R_HUMAN relationship: location_of CCO:B0055359 ! PE2R2_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055372 ! GPR3_HUMAN relationship: location_of CCO:B0055373 ! GPR1_HUMAN relationship: location_of CCO:B0055374 ! XCR1_HUMAN relationship: location_of CCO:B0055378 ! BKRB1_HUMAN relationship: location_of CCO:B0055386 ! RGR_HUMAN relationship: location_of CCO:B0055391 ! OR3A2_HUMAN relationship: location_of CCO:B0055393 ! 5HT5A_HUMAN relationship: location_of CCO:B0055395 ! V1BR_HUMAN relationship: location_of CCO:B0055398 ! TNFL6_HUMAN relationship: location_of CCO:B0055400 ! T4S4_HUMAN relationship: location_of CCO:B0055406 ! INAR2_HUMAN relationship: location_of CCO:B0055413 ! CD97_HUMAN relationship: location_of CCO:B0055414 ! G109B_HUMAN relationship: location_of CCO:B0055418 ! NPY2R_HUMAN relationship: location_of CCO:B0055419 ! PTH2R_HUMAN relationship: location_of CCO:B0055420 ! CX3C1_HUMAN relationship: location_of CCO:B0055428 ! CXCR3_HUMAN relationship: location_of CCO:B0055429 ! PRLHR_HUMAN relationship: location_of CCO:B0055430 ! GPR15_HUMAN relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0055442 ! AGTR2_HUMAN relationship: location_of CCO:B0055446 ! MMP14_HUMAN relationship: location_of CCO:B0055447 ! NPY4R_HUMAN relationship: location_of CCO:B0055449 ! 5HT6R_HUMAN relationship: location_of CCO:B0055455 ! TNF10_HUMAN relationship: location_of CCO:B0055456 ! LU_HUMAN relationship: location_of CCO:B0055468 ! P2RX1_HUMAN relationship: location_of CCO:B0055472 ! CCR3_HUMAN relationship: location_of CCO:B0055473 ! CCR4_HUMAN relationship: location_of CCO:B0055474 ! CCR5_HUMAN relationship: location_of CCO:B0055475 ! CCR6_HUMAN relationship: location_of CCO:B0055476 ! CCR8_HUMAN relationship: location_of CCO:B0055477 ! CCR9_HUMAN relationship: location_of CCO:B0055526 ! BI1_HUMAN relationship: location_of CCO:B0055544 ! P2RX3_HUMAN relationship: location_of CCO:B0055639 ! ACCN2_HUMAN relationship: location_of CCO:B0055686 ! IL9R_HUMAN relationship: location_of CCO:B0055687 ! CD83_HUMAN relationship: location_of CCO:B0055697 ! SC6A3_HUMAN relationship: location_of CCO:B0055699 ! ROR1_HUMAN relationship: location_of CCO:B0055715 ! TIE2_HUMAN relationship: location_of CCO:B0055724 ! PTHR1_HUMAN relationship: location_of CCO:B0055738 ! MUC24_HUMAN relationship: location_of CCO:B0055780 ! TNR9_HUMAN relationship: location_of CCO:B0055781 ! AMPE_HUMAN relationship: location_of CCO:B0055793 ! CD47_HUMAN relationship: location_of CCO:B0055836 ! BST2_HUMAN relationship: location_of CCO:B0055856 ! PTPRJ_HUMAN relationship: location_of CCO:B0055864 ! TSN31_HUMAN relationship: location_of CCO:B0055895 ! GPR17_HUMAN relationship: location_of CCO:B0055896 ! PTK7_HUMAN relationship: location_of CCO:B0055898 ! CRFR2_HUMAN relationship: location_of CCO:B0055916 ! VPP3_HUMAN relationship: location_of CCO:B0055937 ! 5HT4R_HUMAN relationship: location_of CCO:B0055940 ! AVR2B_HUMAN relationship: location_of CCO:B0055945 ! ENPP2_HUMAN relationship: location_of CCO:B0055975 ! EMR1_HUMAN relationship: location_of CCO:B0055983 ! GP176_HUMAN relationship: location_of CCO:B0055990 ! S29A2_HUMAN relationship: location_of CCO:B0056042 ! P2RY6_HUMAN relationship: location_of CCO:B0056043 ! RAGE_HUMAN relationship: location_of CCO:B0056100 ! LT4R1_HUMAN relationship: location_of CCO:B0056104 ! GPR19_HUMAN relationship: location_of CCO:B0056105 ! NPY5R_HUMAN relationship: location_of CCO:B0056107 ! EFNB3_HUMAN relationship: location_of CCO:B0056149 ! LY6E_HUMAN relationship: location_of CCO:B0056178 ! DDR2_HUMAN relationship: location_of CCO:B0056199 ! MICB_HUMAN relationship: location_of CCO:B0056200 ! MICA_HUMAN relationship: location_of CCO:B0056916 ! TRAT1_HUMAN relationship: location_of CCO:B0056952 ! I27RA_HUMAN relationship: location_of CCO:B0057273 ! KCMB4_HUMAN relationship: location_of CCO:B0057306 ! PDPN_HUMAN relationship: location_of CCO:B0057307 ! HOME1_HUMAN relationship: location_of CCO:B0057337 ! GRP3_HUMAN relationship: location_of CCO:B0057446 ! NLGN1_HUMAN relationship: location_of CCO:B0057459 ! LIRB2_HUMAN relationship: location_of CCO:B0057560 ! CLC1A_HUMAN relationship: location_of CCO:B0058062 ! NICA_HUMAN relationship: location_of CCO:B0058076 ! LPAR1_HUMAN relationship: location_of CCO:B0058121 ! TNR25_HUMAN relationship: location_of CCO:B0058164 ! APH1A_HUMAN relationship: location_of CCO:B0058213 ! P2Y11_HUMAN relationship: location_of CCO:B0058328 ! DCBD2_HUMAN relationship: location_of CCO:B0058407 ! CSF3R_HUMAN relationship: location_of CCO:B0058413 ! NPY6R_HUMAN relationship: location_of CCO:B0058414 ! NOTC4_HUMAN relationship: location_of CCO:B0058418 ! S1PR3_HUMAN relationship: location_of CCO:B0058422 ! GPER_HUMAN relationship: location_of CCO:B0058423 ! P2RX4_HUMAN relationship: location_of CCO:B0058438 ! GPR20_HUMAN relationship: location_of CCO:B0058439 ! GPR21_HUMAN relationship: location_of CCO:B0058440 ! GPR22_HUMAN relationship: location_of CCO:B0058444 ! MCHR1_HUMAN relationship: location_of CCO:B0058445 ! KI2L4_HUMAN relationship: location_of CCO:B0058454 ! CML1_HUMAN relationship: location_of CCO:B0058667 ! OPN3_HUMAN relationship: location_of CCO:B0058691 ! CLC4M_HUMAN relationship: location_of CCO:B0058773 ! ILRL2_HUMAN relationship: location_of CCO:B0058780 ! NMUR1_HUMAN relationship: location_of CCO:B0058814 ! GPVI_HUMAN relationship: location_of CCO:B0058846 ! LT4R2_HUMAN relationship: location_of CCO:B0058851 ! FZD3_HUMAN relationship: location_of CCO:B0058853 ! IL1AP_HUMAN relationship: location_of CCO:B0058883 ! Q9NR26_HUMAN relationship: location_of CCO:B0058918 ! RL3R1_HUMAN relationship: location_of CCO:B0058957 ! CLC5A_HUMAN relationship: location_of CCO:B0058989 ! PEN2_HUMAN relationship: location_of CCO:B0059014 ! KLRF1_HUMAN relationship: location_of CCO:B0059015 ! BFAR_HUMAN relationship: location_of CCO:B0059074 ! XPR1_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059113 ! MARCO_HUMAN relationship: location_of CCO:B0059146 ! CLC2D_HUMAN relationship: location_of CCO:B0059195 ! O52A1_HUMAN relationship: location_of CCO:B0059196 ! MUC12_HUMAN relationship: location_of CCO:B0059202 ! TRHDE_HUMAN relationship: location_of CCO:B0059241 ! CLC4A_HUMAN relationship: location_of CCO:B0059259 ! GPR34_HUMAN relationship: location_of CCO:B0059316 ! GPR52_HUMAN relationship: location_of CCO:B0059317 ! GPR55_HUMAN relationship: location_of CCO:B0059330 ! SIGL9_HUMAN relationship: location_of CCO:B0059362 ! RPGF2_HUMAN relationship: location_of CCO:B0059369 ! LRP12_HUMAN relationship: location_of CCO:B0059379 ! HRH3_HUMAN relationship: location_of CCO:B0059392 ! NPFF2_HUMAN relationship: location_of CCO:B0059393 ! GPR44_HUMAN relationship: location_of CCO:B0059397 ! GPR56_HUMAN relationship: location_of CCO:B0062787 ! STX8_HUMAN relationship: location_of CCO:B0062832 ! EAA3_HUMAN relationship: location_of CCO:B0062844 ! AQP5_HUMAN relationship: location_of CCO:B0062852 ! KELL_HUMAN relationship: location_of CCO:B0062978 ! HPS1_HUMAN relationship: location_of CCO:B0063145 ! CTLA4_HUMAN relationship: location_of CCO:B0063192 ! TRPC3_HUMAN relationship: location_of CCO:B0063198 ! SORL_HUMAN relationship: location_of CCO:B0063227 ! MEP1B_HUMAN relationship: location_of CCO:B0063239 ! ICAM3_HUMAN relationship: location_of CCO:B0063267 ! ACCN1_HUMAN relationship: location_of CCO:B0063273 ! GHR_HUMAN relationship: location_of CCO:B0063340 ! 2DRA_HUMAN relationship: location_of CCO:B0063358 ! ADT1_HUMAN relationship: location_of CCO:B0063389 ! T4S1_HUMAN relationship: location_of CCO:B0063404 ! APOM_HUMAN relationship: location_of CCO:B0063454 ! CD48_HUMAN relationship: location_of CCO:B0063455 ! EPCR_HUMAN relationship: location_of CCO:B0063478 ! FXYD3_HUMAN relationship: location_of CCO:B0064022 ! C3AR_HUMAN-Sulfotyrosine174 relationship: location_of CCO:B0064030 ! C5AR_HUMAN-Phosphoserine327 relationship: location_of CCO:B0064121 ! CCR10_HUMAN-Phosphothreonine295 relationship: location_of CCO:B0064123 ! CCR2_HUMAN-Sulfotyrosine26 relationship: location_of CCO:B0064135 ! CD19_HUMAN-Phosphotyrosine378 relationship: location_of CCO:B0064139 ! CD226_HUMAN-Phosphoserine290 relationship: location_of CCO:B0064151 ! CD33_HUMAN-Phosphotyrosine340 relationship: location_of CCO:B0064160 ! CD3G_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0064171 ! CD5_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0064255 ! CELR1_HUMAN-Phosphoserine2761 relationship: location_of CCO:B0064377 ! CLC1B_HUMAN-Phosphotyrosine7 relationship: location_of CCO:B0064430 ! CNTP1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0064552 ! CSF1R_HUMAN-Phosphothreonine562 relationship: location_of CCO:B0064565 ! CSPG4_HUMAN-Phosphothreonine21 relationship: location_of CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: location_of CCO:B0065046 ! EM55_HUMAN-Phosphoserine19 relationship: location_of CCO:B0065089 ! EPHB3_HUMAN-Phosphotyrosine600 relationship: location_of CCO:B0065098 ! EPOR_HUMAN-Phosphotyrosine504 relationship: location_of CCO:B0065229 ! AA3R_HUMAN-Phosphoserine317 relationship: location_of CCO:B0065230 ! AAAT_HUMAN-Phosphoserine535 relationship: location_of CCO:B0065314 ! ACCN3_HUMAN-Phosphoserine521 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: location_of CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: location_of CCO:B0065409 ! ADCY9_HUMAN-Phosphoserine610 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0065817 ! CALY_HUMAN-Phosphotyrosine151 relationship: location_of CCO:B0065818 ! CAPR1_HUMAN-Phosphoserine611 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: location_of CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: location_of CCO:B0066149 ! FCERG_HUMAN-Phosphotyrosine76 relationship: location_of CCO:B0066173 ! FFAR1_HUMAN-Phosphotyrosine44 relationship: location_of CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 relationship: location_of CCO:B0066536 ! GP1BB_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 relationship: location_of CCO:B0066544 ! GPR12_HUMAN-Phosphoserine332 relationship: location_of CCO:B0066549 ! GPR6_HUMAN-Phosphoserine356 relationship: location_of CCO:B0066627 ! GRM1_HUMAN-Phosphotyrosine1109 relationship: location_of CCO:B0066869 ! HNRPM_HUMAN-Phosphoserine432 relationship: location_of CCO:B0066895 ! HRH1_HUMAN-Phosphoserine275 relationship: location_of CCO:B0067075 ! IL2RG_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0067079 ! IL4RA_HUMAN-Phosphotyrosine631 relationship: location_of CCO:B0067099 ! INAR1_HUMAN-Phosphotyrosine481 relationship: location_of CCO:B0067114 ! INGR1_HUMAN-Phosphoserine369 relationship: location_of CCO:B0067115 ! INGR2_HUMAN-Phosphoserine198 relationship: location_of CCO:B0067120 ! INSRR_HUMAN-Phosphotyrosine1145 relationship: location_of CCO:B0067166 ! ITPR1_HUMAN-Phosphoserine1598 relationship: location_of CCO:B0067513 ! KTN1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: location_of CCO:B0067681 ! LIRB3_HUMAN-Phosphothreonine480 relationship: location_of CCO:B0067794 ! LTK_HUMAN-Phosphotyrosine672 relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: location_of CCO:B0068148 ! MERTK_HUMAN-Phosphotyrosine754 relationship: location_of CCO:B0068260 ! MPP2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0068815 ! NPHN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0068836 ! NRG3_HUMAN-Phosphoserine119 relationship: location_of CCO:B0068879 ! NTRK1_HUMAN-Phosphotyrosine680 relationship: location_of CCO:B0068884 ! NTRK2_HUMAN-Phosphotyrosine706 relationship: location_of CCO:B0068888 ! NTRK3_HUMAN-Phosphotyrosine705 relationship: location_of CCO:B0068975 ! OPSD_HUMAN-Phosphoserine343 relationship: location_of CCO:B0069007 ! OX1R_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0069014 ! P2RX5_HUMAN-Phosphotyrosine55 relationship: location_of CCO:B0069015 ! P2RX6_HUMAN-Phosphotyrosine54 relationship: location_of CCO:B0069016 ! P2RX7_HUMAN-Phosphotyrosine343 relationship: location_of CCO:B0069018 ! P2RY1_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069020 ! P2RY4_HUMAN-Phosphoserine334 relationship: location_of CCO:B0069088 ! PALM_HUMAN-Phosphothreonine158 relationship: location_of CCO:B0069291 ! PI2R_HUMAN-Cysteine methyl ester383 relationship: location_of CCO:B0069329 ! PKD1_HUMAN-Phosphoserine4288 relationship: location_of CCO:B0069720 ! RAI3_HUMAN-Phosphotyrosine347 relationship: location_of CCO:B0070125 ! ROBO1_HUMAN-Phosphotyrosine1038 relationship: location_of CCO:B0070139 ! RON_HUMAN-Phosphotyrosine1360 relationship: location_of CCO:B0070144 ! ROR2_HUMAN-Phosphotyrosine646 relationship: location_of CCO:B0070277 ! S20A1_HUMAN-Phosphoserine265 relationship: location_of CCO:B0070287 ! S38A3_HUMAN-Phosphoserine54 relationship: location_of CCO:B0070556 ! SIT1_HUMAN-Phosphotyrosine127 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071644 ! TYOBP_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0071646 ! TYRO3_HUMAN-Phosphotyrosine686 relationship: location_of CCO:B0071808 ! VIPR1_HUMAN-Phosphoserine449 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000446 name: hydrogen:potassium-exchanging ATPase complex namespace: cellular_component def: "A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of Na+ and K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present." [PMID:11756431] synonym: "hydrogen/potassium-exchanging ATPase complex" EXACT [] synonym: "proton pump" BROAD [] xref: GO:0005889 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000447 name: sodium:potassium-exchanging ATPase complex namespace: cellular_component def: "Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "sodium pump" BROAD [] synonym: "sodium/potassium-exchanging ATPase complex" EXACT [] xref: GO:0005890 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0010637 ! AT1A1_HUMAN-Phosphothreonine219 relationship: location_of CCO:B0031296 ! AT1B1_HUMAN-Phosphotyrosine101 relationship: location_of CCO:B0052705 ! ROS_HUMAN-Phosphotyrosine2114 relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000448 name: voltage-gated calcium channel complex namespace: cellular_component def: "A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential." [GOC:mah] subset: goslim_pir synonym: "voltage gated calcium channel complex" EXACT [] synonym: "voltage-dependent calcium channel complex" EXACT [] synonym: "voltage-sensitive calcium channel complex" EXACT [] xref: GO:0005891 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005692 ! CAC1C_HUMAN relationship: location_of CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: location_of CCO:B0010887 ! CACB4_HUMAN-Phosphoserine508 relationship: location_of CCO:B0059035 ! CAC1I_HUMAN relationship: location_of CCO:B0064043 ! CAC1D_HUMAN-Phosphoserine1475 relationship: location_of CCO:B0064045 ! CACB3_HUMAN-Phosphotyrosine171 [Term] id: CCO:C0000449 name: nicotinic acetylcholine-gated receptor-channel complex namespace: cellular_component def: "A protein complex that acts as an acetylcholine receptor, and forms a transmembrane channel through which ions may pass in response to ligand binding. The complex is a homo- or heteropentamer of subunits that are members of a neurotransmitter receptor superfamily." [GOC:mah, PMID:12381728, PMID:15579462] synonym: "nicotinic acetylcholine receptor" BROAD [] xref: GO:0005892 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0032799 ! ACHB3_HUMAN relationship: location_of CCO:B0032804 ! ACHA3_HUMAN relationship: location_of CCO:B0032806 ! ACHA5_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0032809 ! ACHA2_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000450 name: interleukin-2 receptor complex namespace: cellular_component def: "Complex that binds interleukin-2; comprises alpha, beta, and gamma subunits." [GOC:mah, PMID:3116143, PMID:8266078] xref: GO:0005893 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000451 name: interleukin-3 receptor complex namespace: cellular_component def: "Complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5." [PMID:11839579] xref: GO:0005894 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000452 name: interleukin-5 receptor complex namespace: cellular_component def: "Complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3." [GOC:mah, PMID:11312115, PMID:11839579] xref: GO:0005895 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0056005 ! Q14632_HUMAN relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000453 name: interleukin-6 receptor complex namespace: cellular_component def: "A hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130." [PMID:8083235] xref: GO:0005896 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0054933 ! IL6RA_HUMAN relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000454 name: interleukin-9 receptor complex namespace: cellular_component def: "Complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins." [GOC:mah, PMID:10642536] xref: GO:0005897 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000455 name: interleukin-13 receptor complex namespace: cellular_component def: "A complex that binds interleukin-13; consists of two chains, interleukin-4 receptor alpha chain and interleukin-4 receptor alpha chain." [UniProtKB:P78552] xref: GO:0005898 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0055652 ! I13R1_HUMAN relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000456 name: insulin receptor complex namespace: cellular_component def: "A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005899 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000457 name: oncostatin-M receptor complex namespace: cellular_component def: "A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta." [GOC:jl, PMID:8999038] xref: GO:0005900 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0068996 ! OSMR_HUMAN-Phosphotyrosine837 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000458 name: caveola namespace: cellular_component def: "A small pit, depression, or invagination, such as any of the minute pits or incuppings of the cell membrane formed during pinocytosis, that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Such caveolae may be pinched off to form free vesicles within the cytoplasm." [http://cancerweb.ncl.ac.uk/, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] synonym: "caveolae" EXACT [] synonym: "caveolar membrane" RELATED [] xref: GO:0005901 xref: GO:0016599 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0002123 ! membrane raft relationship: location_of CCO:B0001557 ! PAR1_HUMAN relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: location_of CCO:B0012863 ! MDC1_HUMAN-Phosphothreonine523 relationship: location_of CCO:B0033477 ! LRP8_HUMAN relationship: location_of CCO:B0035571 ! RHG07_HUMAN-Phosphoserine305 relationship: location_of CCO:B0052463 ! IRS1_HUMAN-Phosphotyrosine632 relationship: location_of CCO:B0054589 ! NSMA_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055534 ! CAD13_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0070904 ! SRC_HUMAN-Phosphotyrosine439 [Term] id: CCO:C0000459 name: microvillus namespace: cellular_component def: "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." [ISBN:0813516194] subset: goslim_pir xref: GO:0005902 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0056953 ! ENPP7_HUMAN relationship: location_of CCO:B0062844 ! AQP5_HUMAN relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0071167 ! TB10A_HUMAN-Phosphoserine407 [Term] id: CCO:C0000460 name: brush border namespace: cellular_component def: "Dense covering of microvilli on the apical surface of epithelial cells in the intestine and kidney; the microvilli aid absorption by increasing the surface area of the cell." [ISBN:0815316194] subset: goslim_pir xref: GO:0005903 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0055781 ! AMPE_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0067173 ! ITPR3_HUMAN-Phosphoserine1832 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 [Term] id: CCO:C0000461 name: plasma membrane lipid bilayer namespace: cellular_component def: "The phospholipid membrane surrounding a cell that separates the cell from its external environment, excluding intergral and associated proteins." [GOC:go_curators] xref: GO:0005904 is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0000462 name: coated pit namespace: cellular_component def: "An invagination of the cell membrane of many eukaryotic cells, concerned in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane. During endocytosis it is converted into a coated vesicle. The coat is of clathrin." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005905 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005197 ! AP2B1_HUMAN relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: location_of CCO:B0011260 ! CLH2_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0011697 ! EP15_HUMAN-Phosphoserine324 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0014052 ! SH3B4_HUMAN-Phosphoserine637 relationship: location_of CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: location_of CCO:B0055510 ! AP2S1_HUMAN relationship: location_of CCO:B0055669 ! VLDLR_HUMAN relationship: location_of CCO:B0056054 ! RAB35_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0059369 ! LRP12_HUMAN relationship: location_of CCO:B0062791 ! NECP2_HUMAN relationship: location_of CCO:B0062824 ! AP2M1_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063531 ! CLCB_HUMAN relationship: location_of CCO:B0064623 ! DAB2_HUMAN-Phosphoserine401 relationship: location_of CCO:B0066010 ! EPN1_HUMAN-Phosphoserine395 relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 [Term] id: CCO:C0000463 name: intercellular junction namespace: cellular_component def: "A specialized region of connection between two cells including but not limited to gap junctions, desmosomes, and tight junctions, but excluding direct cytoplasmic junctions such as ring canals." [GOC:dgh, GOC:hb] synonym: "cell-cell junction" EXACT [] xref: GO:0005911 is_a: CCO:C0000936 ! cell junction relationship: location_of CCO:B0002110 ! CADM1_HUMAN relationship: location_of CCO:B0011355 ! CSK_HUMAN-Phosphotyrosine304 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0054348 ! BAI1_HUMAN relationship: location_of CCO:B0056646 ! MRCKA_HUMAN relationship: location_of CCO:B0058358 ! MAGI1_HUMAN relationship: location_of CCO:B0064416 ! CNKR1_HUMAN-Phosphoserine305 relationship: location_of CCO:B0065466 ! AFAD_HUMAN-Phosphoserine215 relationship: location_of CCO:B0065965 ! E41L3_HUMAN-Phosphothreonine703 relationship: location_of CCO:B0068275 ! MRCKB_HUMAN-Phosphoserine221 relationship: location_of CCO:B0069380 ! PKP2_HUMAN-Phosphoserine329 [Term] id: CCO:C0000464 name: adherens junction namespace: cellular_component def: "A cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005912 is_a: CCO:C0000936 ! cell junction relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0030278 ! RND1_HUMAN relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 [Term] id: CCO:C0000465 name: cell-cell adherens junction namespace: cellular_component def: "An adherens junction which connects two cells to each other." [GOC:hb] xref: GO:0005913 is_a: CCO:C0000463 ! intercellular junction is_a: CCO:C0000464 ! adherens junction relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000466 name: spot adherens junction namespace: cellular_component def: "A small junction assombled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens." [PMID:11700298] synonym: "dense plaque" BROAD [] synonym: "punctum adherens" EXACT [] xref: GO:0005914 is_a: CCO:C0000465 ! cell-cell adherens junction [Term] id: CCO:C0000467 name: zonula adherens namespace: cellular_component def: "Cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells." [ISBN:0815316208] synonym: "belt desmosome" EXACT [] synonym: "intermediate junction" EXACT [] xref: GO:0005915 is_a: CCO:C0000465 ! cell-cell adherens junction relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: part_of CCO:C0001769 ! apical junction complex [Term] id: CCO:C0000468 name: fascia adherens namespace: cellular_component def: "An electron dense junctional complex, at the end to end contacts of cardiac muscle cells, that contains gap junctions and desmosomes. Most of the disc is formed of a convoluted fascia adherens type of junction into which the actin filaments of the terminal sarcomeres insert (or in the case of muscle cells, myofibrils), desmosomes are also present. The lateral portion of the stepped disc contains gap junctions that couple the cells electrically and thus coordinate the contraction." [GOC:mtg_muscle, http://cancerweb.ncl.ac.uk] xref: GO:0005916 is_a: CCO:C0000465 ! cell-cell adherens junction relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: part_of CCO:C0000743 ! intercalated disc [Term] id: CCO:C0000469 name: nephrocyte junction namespace: cellular_component def: "A tissue-specific adherens junction found in kidney cells." [http://flybase.bio.indiana.edu/allied-data/lk/interactive-fly/aignfam/junction.htm] xref: GO:0005917 is_a: CCO:C0000465 ! cell-cell adherens junction [Term] id: CCO:C0000470 name: septate junction namespace: cellular_component def: "Invertebrate-specific cell-cell junctions which form a band around the apical borders of epithelial cells and attach to actin filaments." [ISBN:0815316208] synonym: "septate desmosome" RELATED [] xref: GO:0005918 is_a: CCO:C0000465 ! cell-cell adherens junction relationship: part_of CCO:C0001769 ! apical junction complex [Term] id: CCO:C0000471 name: pleated septate junction namespace: cellular_component def: "A septate junction in which regular arrays of electron-dense septae span the intermembrane space." [PMID:11700298] synonym: "pleated desmosome" RELATED [] xref: GO:0005919 is_a: CCO:C0000470 ! septate junction [Term] id: CCO:C0000472 name: smooth septate junction namespace: cellular_component def: "A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions." [PMID:11700298] synonym: "zonula continua" EXACT [] xref: GO:0005920 is_a: CCO:C0000470 ! septate junction [Term] id: CCO:C0000473 name: gap junction namespace: cellular_component def: "Any specialized areas of the plasma membranes of adjacent cells where the membranes are 2-4 nm apart and penetrated by a connexon. This gap junction allows passage of small molecules and electric current. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junction." [GOC:mtg_muscle, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "communicating junction" EXACT [] synonym: "macula communicans" EXACT [] synonym: "zonula communicans" EXACT [] xref: GO:0005921 is_a: CCO:C0000463 ! intercellular junction relationship: location_of CCO:B0006029 ! PANX3_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: part_of CCO:C0000743 ! intercalated disc [Term] id: CCO:C0000474 name: connexon complex namespace: cellular_component def: "An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction." [PMID:11146276] xref: GO:0005922 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: part_of CCO:C0000473 ! gap junction [Term] id: CCO:C0000475 name: tight junction namespace: cellular_component def: "A belt-like region of very close contact between the plasma membranes of adjacent cells so that the intercellular space is completely occluded. They occur in epithelia and brain endothelia." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "zonula occludens" EXACT [] xref: GO:0005923 is_a: CCO:C0000463 ! intercellular junction relationship: location_of CCO:B0002112 ! PAR6G_HUMAN relationship: location_of CCO:B0002113 ! PAR6B_HUMAN relationship: location_of CCO:B0002150 ! PAR6A_HUMAN relationship: location_of CCO:B0005299 ! AMOL2_HUMAN relationship: location_of CCO:B0005934 ! WNK4_HUMAN relationship: location_of CCO:B0013388 ! PAR3L_HUMAN-Phosphoserine730 relationship: location_of CCO:B0013393 ! PARD3_HUMAN-Phosphoserine717 relationship: location_of CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0019132 ! RHG17_HUMAN relationship: location_of CCO:B0049698 ! CLD7_HUMAN relationship: location_of CCO:B0058358 ! MAGI1_HUMAN relationship: location_of CCO:B0059029 ! VAPA_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0063628 ! ASH1L_HUMAN-Phosphoserine22 relationship: location_of CCO:B0065618 ! AMOT_HUMAN-Phosphoserine312 relationship: location_of CCO:B0065880 ! CLD12_HUMAN-Phosphoserine228 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: location_of CCO:B0067093 ! INADL_HUMAN-Phosphoserine455 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0069665 ! RAB13_HUMAN-Phosphoserine178 relationship: location_of CCO:B0072275 ! ZO3_HUMAN-Phosphoserine579 relationship: part_of CCO:C0001769 ! apical junction complex [Term] id: CCO:C0000476 name: cell-substrate adherens junction namespace: cellular_component def: "An adherens junction which connects a cell to the extracellular matrix." [GOC:hb] synonym: "hemi-adherens junction" RELATED [] xref: GO:0005924 is_a: CCO:C0000464 ! adherens junction is_a: CCO:C0002136 ! cell-substrate junction relationship: location_of CCO:B0068587 ! NEXN_HUMAN-Phosphoserine365 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 [Term] id: CCO:C0000477 name: focal adhesion namespace: cellular_component def: "Small region on the surface of a cell that anchors the cell to the extracellular matrix and that are points of termination of actin filaments." [ISBN:0124325653, ISBN:0815316208] synonym: "focal contact" EXACT [] synonym: "hemi-adherens junction" EXACT [] xref: GO:0005925 xref: GO:0008357 is_a: CCO:C0000476 ! cell-substrate adherens junction relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005642 ! ACTN2_HUMAN relationship: location_of CCO:B0005948 ! ACTN1_HUMAN relationship: location_of CCO:B0005985 ! TRIP6_HUMAN relationship: location_of CCO:B0010760 ! BCAR1_HUMAN-Phosphotyrosine362 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011050 ! CD45_HUMAN-Phosphoserine1003 relationship: location_of CCO:B0011824 ! FAK1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011839 ! FAK2_HUMAN-Phosphotyrosine881 relationship: location_of CCO:B0012698 ! LIMK1_HUMAN-Phosphoserine298 relationship: location_of CCO:B0020080 ! ACTN3_HUMAN relationship: location_of CCO:B0035571 ! RHG07_HUMAN-Phosphoserine305 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0052719 ! S10A7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0054133 ! A8MYY5_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0055907 ! ILK_HUMAN relationship: location_of CCO:B0056411 ! Q59GM6_HUMAN relationship: location_of CCO:B0056693 ! Q658W2_HUMAN relationship: location_of CCO:B0056892 ! Q6P5Z4_HUMAN relationship: location_of CCO:B0056928 ! Q6QEF7_HUMAN relationship: location_of CCO:B0057392 ! Q8IYN9_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0065175 ! EVL_HUMAN-Phosphoserine306 relationship: location_of CCO:B0067657 ! LIMA1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0071331 ! TENC1_HUMAN-Phosphoserine835 relationship: location_of CCO:B0071803 ! VINEX_HUMAN-Phosphothreonine529 relationship: location_of CCO:B0072283 ! ZYX_HUMAN-Phosphothreonine270 [Term] id: CCO:C0000478 name: connecting hemi-adherens junction namespace: cellular_component def: "A hemiadherens junction (HAJ) that forms one of a pair of HAJs in opposing cells that are separated by only 30-40nm, with a thin line of extracellular electron-dense material in between; found where muscles attach to epidermal cells directly (in insects)." [http://flybase.bio.indiana.edu/allied-data/lk/interactive-fly/aignfam/junction.htm] xref: GO:0005926 is_a: CCO:C0000476 ! cell-substrate adherens junction [Term] id: CCO:C0000479 name: muscle tendon junction namespace: cellular_component def: "Terminal anchorage site of skeletal muscle cells to tendons; a specialised type of contact between the cell and the extracellular matrix in skeletal muscle." [GOC:mtg_muscle, PMID:12842007] synonym: "myotendinous junction" EXACT [] xref: GO:0005927 is_a: CCO:C0000476 ! cell-substrate adherens junction relationship: location_of CCO:B0058484 ! NEUL2_HUMAN [Term] id: CCO:C0000480 name: apical hemi-adherens junction namespace: cellular_component def: "An adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle." [GOC:mah, PMID:11700298] synonym: "apical dense plaque" EXACT [] xref: GO:0005928 is_a: CCO:C0000476 ! cell-substrate adherens junction [Term] id: CCO:C0000481 name: cilium namespace: cellular_component def: "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:kva, ISBN:0198547684] subset: goslim_generic subset: goslim_pir xref: GO:0005929 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0002099 ! CP250_HUMAN relationship: location_of CCO:B0006039 ! SMO_HUMAN relationship: location_of CCO:B0006167 ! TBB4_HUMAN relationship: location_of CCO:B0006333 ! TTLL5_HUMAN relationship: location_of CCO:B0013541 ! PKD2_HUMAN-Phosphoserine254 relationship: location_of CCO:B0054609 ! NPHP4_HUMAN relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0055552 ! RP1_HUMAN relationship: location_of CCO:B0055823 ! DYH14_HUMAN relationship: location_of CCO:B0058028 ! DYH12_HUMAN relationship: location_of CCO:B0058936 ! IFT57_HUMAN relationship: location_of CCO:B0062879 ! CTSR1_HUMAN relationship: location_of CCO:B0064039 ! CABYR_HUMAN-Phosphoserine362 relationship: location_of CCO:B0065551 ! AKAP4_HUMAN-Phosphoserine492 [Term] id: CCO:C0000482 name: axoneme namespace: cellular_component def: "The bundle of microtubules and associated proteins that forms the core of cilia and flagella in eukaryotic cells and is responsible for their movements." [ISBN:0198547684] xref: GO:0005930 is_a: CCO:C0001881 ! cell projection part relationship: location_of CCO:B0055873 ! IFT88_HUMAN relationship: part_of CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0000483 name: nexin complex namespace: cellular_component def: "A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005931 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part [Term] id: CCO:C0000484 name: basal body namespace: cellular_component def: "A short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium or flagellum that is similar in structure to a centriole. The basal body serves as a nucleation site for axoneme growth." [GOC:clt] xref: GO:0005932 is_a: CCO:C0000385 ! microtubule organizing center is_a: CCO:C0001881 ! cell projection part relationship: location_of CCO:B0013541 ! PKD2_HUMAN-Phosphoserine254 relationship: location_of CCO:B0043419 ! BBS2_HUMAN relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: location_of CCO:B0055873 ! IFT88_HUMAN relationship: location_of CCO:B0057919 ! PKHD1_HUMAN relationship: location_of CCO:B0058936 ! IFT57_HUMAN [Term] id: CCO:C0000485 name: cellular bud namespace: cellular_component def: "A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated." [GOC:sgd_curators] subset: goslim_candida subset: goslim_pir subset: goslim_yeast xref: GO:0005933 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000486 name: cellular bud tip namespace: cellular_component def: "The end of a cellular bud distal to the site of attachment to the mother cell." [GOC:mah] xref: GO:0005934 is_a: CCO:C0001007 ! site of polarized growth relationship: part_of CCO:C0000485 ! cellular bud [Term] id: CCO:C0000487 name: cellular bud neck namespace: cellular_component def: "The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding." [GOC:mah] xref: GO:0005935 is_a: CCO:C0001007 ! site of polarized growth relationship: part_of CCO:C0000485 ! cellular bud [Term] id: CCO:C0000488 name: mating projection namespace: cellular_component def: "The projection formed by unicellular fungi in response to mating pheromone." [GOC:mcc] subset: goslim_pir synonym: "conjugation tube" NARROW [] synonym: "shmoo" NARROW [] xref: GO:0005937 is_a: CCO:C0001706 ! cell projection [Term] id: CCO:C0000489 name: cell cortex namespace: cellular_component def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_yeast synonym: "cell periphery" RELATED [] synonym: "peripheral cytoplasm" RELATED [] xref: GO:0005938 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0002113 ! PAR6B_HUMAN relationship: location_of CCO:B0002150 ! PAR6A_HUMAN relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013270 ! NUCL_HUMAN-Phosphoserine34 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0032855 ! MYH10_HUMAN-Phosphothreonine1960 relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0052277 ! ADSV_HUMAN-Phosphotyrosine599 relationship: location_of CCO:B0054391 ! GIPC1_HUMAN relationship: location_of CCO:B0054577 ! CYTIP_HUMAN relationship: location_of CCO:B0055508 ! ARFP2_HUMAN relationship: location_of CCO:B0055616 ! ARF6_HUMAN relationship: location_of CCO:B0058862 ! ISK5_HUMAN relationship: location_of CCO:B0059177 ! DBNL_HUMAN relationship: location_of CCO:B0063370 ! SRC8_HUMAN relationship: location_of CCO:B0064416 ! CNKR1_HUMAN-Phosphoserine305 [Term] id: CCO:C0000490 name: septin ring namespace: cellular_component def: "A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form." [GOC:krc, GOC:mah, PMID:16009555, PMID:16151244] synonym: "septin ring (sensu Fungi)" NARROW [] xref: GO:0005940 xref: GO:0030481 is_a: CCO:C0001405 ! septin cytoskeleton is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001867 ! cell cortex part [Term] id: CCO:C0000492 name: phosphoinositide 3-kinase complex namespace: cellular_component def: "A complex containing a heterodimer of a catalytic subunit and a regulatory (adaptor) subunit of any phosphoinositide 3-kinase (PI3K)." [GOC:bf] subset: goslim_pir synonym: "1-phosphatidylinositol 3-kinase complex" EXACT [] synonym: "PI3K complex" EXACT [] xref: GO:0005942 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0001610 ! PK3CB_HUMAN relationship: location_of CCO:B0001611 ! FRAP_HUMAN relationship: location_of CCO:B0005326 ! PK3CG_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0010419 ! ABL2_HUMAN-Phosphothreonine440 relationship: location_of CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 relationship: location_of CCO:B0018345 ! O00334_HUMAN relationship: location_of CCO:B0018350 ! PK3CA_HUMAN relationship: location_of CCO:B0026606 ! Q05BV6_HUMAN relationship: location_of CCO:B0043340 ! PK3CD_HUMAN-Phosphoserine1039 relationship: location_of CCO:B0054130 ! A8MYT4_HUMAN relationship: location_of CCO:B0054663 ! P3C2G_HUMAN relationship: location_of CCO:B0057589 ! PK3C3_HUMAN relationship: location_of CCO:B0064632 ! DAPP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0069024 ! P55G_HUMAN-Phosphotyrosine199 relationship: location_of CCO:B0069034 ! P85A_HUMAN-Phosphotyrosine467 relationship: location_of CCO:B0069040 ! P85B_HUMAN-Phosphotyrosine467 [Term] id: CCO:C0000495 name: 6-phosphofructokinase complex namespace: cellular_component def: "A protein complex that possesses 6-phosphofructokinase activity; homodimeric and allosteric homotetrameric forms are known." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005945 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0034952 ! K6PF_HUMAN-Phosphothreonine2 relationship: location_of CCO:B0034954 ! K6PL_HUMAN-Phosphotyrosine633 [Term] id: CCO:C0000496 name: alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) namespace: cellular_component def: "A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present." [PMID:9837904] comment: See also the molecular function term 'alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity ; GO:0003825'. synonym: "trehalose-6-phosphate synthase complex" EXACT [] synonym: "trehalose-6-phosphate synthase/phosphatase" EXACT [] synonym: "UDP-glucose-glucosephosphate glucosyltransferase complex" EXACT [] xref: GO:0005946 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000497 name: mitochondrial alpha-ketoglutarate dehydrogenase complex namespace: cellular_component def: "Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity." [GOC:mah, GOC:mtg_sensu] synonym: "2-oxoglutarate dehydrogenase complex" BROAD [] synonym: "alpha-ketoglutarate dehydrogenase complex (sensu Eukaryota)" EXACT [] xref: GO:0005947 is_a: CCO:C0000941 ! mitochondrial tricarboxylic acid cycle enzyme complex is_a: CCO:C0001904 ! alpha-ketoglutarate dehydrogenase complex relationship: location_of CCO:B0063238 ! ODBB_HUMAN relationship: location_of CCO:B0063791 ! BCKD_HUMAN-Phosphoserine52 relationship: location_of CCO:B0068953 ! ODBA_HUMAN-Phosphoserine337 [Term] id: CCO:C0000498 name: acetolactate synthase complex namespace: cellular_component def: "A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate." [BRENDA:2.2.1.6, GOC:jl, UniProt:P37252] comment: See also the molecular function term 'acetolactate synthase activity ; GO:0003984'. subset: gosubset_prok synonym: "acetohydroxyacid synthase complex" EXACT [] xref: GO:0005948 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000499 name: anthranilate synthase complex namespace: cellular_component def: "A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine." [EC:4.1.3.27, UniProtKB:P09785] xref: GO:0005950 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000500 name: carbamoyl-phosphate synthase complex namespace: cellular_component def: "A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia moiety cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events." [PMID:8626695] comment: Note that in higher eukaryotes, carbamoyl-phosphate synthase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term. subset: gosubset_prok synonym: "arginine-specific carbamoyl phosphate synthetase complex" NARROW [] synonym: "carbamoyl phosphate synthase complex" EXACT [] synonym: "carbamoyl-phosphate synthase arginine-specific complex" NARROW [] xref: GO:0005951 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000501 name: cAMP-dependent protein kinase complex namespace: cellular_component def: "An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer." [EC:2.7.11.11, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "3',5' cAMP-dependent protein kinase complex" EXACT [] synonym: "3',5'-cAMP-dependent protein kinase complex" EXACT [] synonym: "adenosine 3',5'-cyclophosphate-dependent protein kinase complex" EXACT [] synonym: "cyclic AMP-dependent protein kinase complex" EXACT [] synonym: "PKA" RELATED [] xref: GO:0005952 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0005298 ! KAP0_HUMAN relationship: location_of CCO:B0014816 ! KGP1A_HUMAN relationship: location_of CCO:B0014822 ! KGP1B_HUMAN relationship: location_of CCO:B0017343 ! Q15300_HUMAN relationship: location_of CCO:B0021338 ! Q8N422_HUMAN relationship: location_of CCO:B0022455 ! KAP2_HUMAN relationship: location_of CCO:B0022458 ! Q9BUB1_HUMAN relationship: location_of CCO:B0034961 ! KAP1_HUMAN-Nitrated tyrosine21 relationship: location_of CCO:B0034969 ! KAP3_HUMAN-Phosphoserine114 relationship: location_of CCO:B0034975 ! KAPCA_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0034978 ! KAPCB_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0053748 ! A3R6R8_HUMAN relationship: location_of CCO:B0054240 ! B1ALS0_HUMAN relationship: location_of CCO:B0054757 ! RPGF3_HUMAN relationship: location_of CCO:B0056372 ! Q569L6_HUMAN relationship: location_of CCO:B0056861 ! Q6NUQ6_HUMAN relationship: location_of CCO:B0058055 ! RPGF4_HUMAN relationship: location_of CCO:B0065241 ! AAKB2_HUMAN-Phosphoserine183 relationship: location_of CCO:B0065551 ! AKAP4_HUMAN-Phosphoserine492 [Term] id: CCO:C0000502 name: CAAX-protein geranylgeranyltransferase complex namespace: cellular_component def: "A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane." [PMID:9781874, UniProtKB:P53609] xref: GO:0005953 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000503 name: calcium- and calmodulin-dependent protein kinase complex namespace: cellular_component def: "An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins." [EC:2.7.11.17, UniProtKB:Q9UQM7] synonym: "calcium/calmodulin-dependent protein kinase complex" EXACT [] synonym: "CAMK2" EXACT [] synonym: "CaMKII" RELATED [] xref: GO:0005954 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0067275 ! KCC2D_HUMAN-Phosphoserine315 [Term] id: CCO:C0000504 name: calcineurin complex namespace: cellular_component def: "A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin." [ISBN:019859951] synonym: "calcium-dependent protein serine/threonine phosphatase complex" NARROW [] synonym: "protein phosphatase type 2B complex" EXACT [] xref: GO:0005955 is_a: CCO:C0000541 ! protein serine/threonine phosphatase complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001527 ! PP2BB_HUMAN relationship: location_of CCO:B0016306 ! PP2BA_HUMAN relationship: location_of CCO:B0064058 ! CANB1_HUMAN-Phosphotyrosine106 [Term] id: CCO:C0000505 name: protein kinase CK2 complex namespace: cellular_component def: "Complex that possesses casein kinase activity, found in nearly every subcellular compartment. Protein kinase CK2 complexes are usually tetramers of two alpha and two beta subunits, and can phosphorylate many protein substrates in addition to casein." [GOC:mah, PMID:10994779] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. One function possessed by this complex is represented by the molecular function term 'casein kinase II ; GO:0004682'. synonym: "casein kinase II complex" EXACT [] xref: GO:0005956 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0011351 ! CSK2B_HUMAN-Phosphoserine3 [Term] id: CCO:C0000506 name: DNA-dependent protein kinase complex namespace: cellular_component def: "A large protein complex which is involved in the repair of DNA double-strand breaks and V(D)J recombination events. In mammals, it consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer, Ku, the nuclear phosphoprotein XRCC4 and DNA ligase IV." [GOC:jl, PMID:10854421, PMID:12235392] synonym: "DNA-dependent protein kinase, DNA-end-binding complex" NARROW [] synonym: "DNA-PK complex" EXACT [] xref: GO:0005958 xref: GO:0005959 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0012651 ! KU70_HUMAN-Phosphoserine51 relationship: location_of CCO:B0064815 ! DNLI4_HUMAN-Phosphothreonine347 relationship: location_of CCO:B0069525 ! PRKDC_HUMAN-Phosphoserine4026 relationship: location_of CCO:B0071895 ! XRCC4_HUMAN-Phosphoserine327 [Term] id: CCO:C0000507 name: glycine cleavage complex namespace: cellular_component def: "A multienzyme complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase." [MetaCyc:GCVMULTI-CPLX] subset: goslim_pir subset: gosubset_prok synonym: "glycine cleavage system" EXACT [] synonym: "glycine dehydrogenase complex (decarboxylating)" RELATED [] synonym: "glycine synthase complex" EXACT [] xref: GO:0005960 xref: GO:0005961 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0062899 ! GCSH_HUMAN [Term] id: CCO:C0000509 name: mitochondrial isocitrate dehydrogenase complex (NAD+) namespace: cellular_component def: "Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'isocitrate dehydrogenase (NAD+) activity ; GO:0004449'. synonym: "isocitrate dehydrogenase complex (NAD+) (sensu Eukaryota)" EXACT [] xref: GO:0005962 is_a: CCO:C0000941 ! mitochondrial tricarboxylic acid cycle enzyme complex is_a: CCO:C0001906 ! isocitrate dehydrogenase complex (NAD+) [Term] id: CCO:C0000510 name: magnesium-dependent protein serine/threonine phosphatase complex namespace: cellular_component def: "An enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase." [EC:3.1.3.16] xref: GO:0005963 is_a: CCO:C0000541 ! protein serine/threonine phosphatase complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000511 name: phosphorylase kinase complex namespace: cellular_component def: "An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a." [EC:2.7.11.19] xref: GO:0005964 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000512 name: protein farnesyltransferase complex namespace: cellular_component def: "A protein complex that possesses protein farnesyltransferase activity." [GOC:mah] xref: GO:0005965 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000514 name: mitochondrial pyruvate dehydrogenase complex namespace: cellular_component def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase." [GOC:mtg_sensu, ISBN:0471331309 "Biochemical Pathways", ISBN:0716720094] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'. synonym: "pyruvate dehydrogenase complex (lipoamide) (sensu Eukaryota)" EXACT [] synonym: "pyruvate dehydrogenase complex (sensu Eukaryota)" EXACT [] xref: GO:0005967 is_a: CCO:C0001848 ! mitochondrial part is_a: CCO:C0001917 ! pyruvate dehydrogenase complex relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000515 name: Rab-protein geranylgeranyltransferase complex namespace: cellular_component def: "A heterodimeric enzyme complex, which in mammals is composed of an alpha and a beta subunit, and which associates with an accessory protein Rep (Rab escort protein). Catalyzes of the transfer of a geranyl-geranyl moiety from geranylgeranyl pyrophosphate to a Rab protein." [GOC:jl, PMID:11886217, UniProtKB:Q08602] synonym: "GGTase-II complex" EXACT [] synonym: "Rab geranylgeranyltransferase complex" EXACT [] synonym: "RAB-protein geranylgeranyltransferase complex" EXACT [] synonym: "RabGGTase complex" EXACT [] xref: GO:0005968 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000518 name: ribonucleoside-diphosphate reductase complex namespace: cellular_component def: "An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate and thioredoxin disulfide from ribonucleoside diphosphate and thioredoxin." [BRENDA:1.17.4.1] subset: gosubset_prok xref: GO:0005971 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0006232 ! RIR1_HUMAN [Term] id: CCO:C0000519 name: lamina lucida namespace: cellular_component def: "The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina." [ISBN:0815316194] xref: GO:0008002 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000228 ! basal lamina [Term] id: CCO:C0000520 name: lamina densa namespace: cellular_component def: "The electron-dense layer of the basal lamina; lies just below the lamina lucida." [ISBN:0815316194] xref: GO:0008003 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000228 ! basal lamina [Term] id: CCO:C0000521 name: lamina reticularis namespace: cellular_component def: "A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue." [ISBN:0815316194] xref: GO:0008004 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000228 ! basal lamina [Term] id: CCO:C0000522 name: synaptic vesicle namespace: cellular_component def: "Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane." [PMID:10099709] xref: GO:0008021 is_a: CCO:C0000981 ! clathrin-coated vesicle relationship: location_of CCO:B0002079 ! Q99648_HUMAN relationship: location_of CCO:B0002085 ! SEPT5_HUMAN relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0040086 ! SYT17_HUMAN relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0055185 ! MT3_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0063022 ! APBA1_HUMAN relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0068994 ! OREX_HUMAN-Methionine amide97 relationship: location_of CCO:B0069680 ! RAB3A_HUMAN-Phosphoserine188 relationship: location_of CCO:B0069683 ! RAB3B_HUMAN-Cysteine methyl ester219 relationship: location_of CCO:B0071048 ! SYN1_HUMAN-Phosphotyrosine312 [Term] id: CCO:C0000523 name: transcription elongation factor complex namespace: cellular_component def: "Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation." [GOC:jl] subset: goslim_pir xref: GO:0008023 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0001647 ! CDK9_HUMAN relationship: location_of CCO:B0005398 ! ELP1_HUMAN relationship: location_of CCO:B0006303 ! TCEA2_HUMAN relationship: location_of CCO:B0048582 ! ELP2_HUMAN relationship: location_of CCO:B0054324 ! ELL2_HUMAN relationship: location_of CCO:B0055725 ! ERCC6_HUMAN relationship: location_of CCO:B0058778 ! ELL3_HUMAN relationship: location_of CCO:B0059143 ! NUFP1_HUMAN relationship: location_of CCO:B0065041 ! ELOA1_HUMAN-Phosphoserine125 relationship: location_of CCO:B0065043 ! ELP3_HUMAN-Phosphotyrosine202 relationship: location_of CCO:B0065045 ! ELP4_HUMAN-Phosphoserine42 relationship: location_of CCO:B0071623 ! TTF2_HUMAN-Phosphoserine396 [Term] id: CCO:C0000524 name: transcription elongation factor complex b namespace: cellular_component def: "A complex of cyclin T and a cyclin-dependent protein kinase, catalyst, that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme." [UniProtKB:O60563] comment: See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'. xref: GO:0008024 is_a: CCO:C0000523 ! transcription elongation factor complex [Term] id: CCO:C0000525 name: ferritin complex namespace: cellular_component def: "A iron-storing protein complex, which in humans has 24 subunits. There are two different ferritin subunits, the L (light) chain and H (heavy) chain." [GOC:jl, UniProtKB:P02792] xref: GO:0008043 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0011895 ! FRIL_HUMAN-N-acetylserine2 relationship: location_of CCO:B0034814 ! FRIH_HUMAN-Phosphoserine179 [Term] id: CCO:C0000526 name: guanylate cyclase complex, soluble namespace: cellular_component def: "Complex that possesses guanylate cyclase activity and is not bound to a membrane." [GOC:mah] comment: See also the molecular function term 'guanylate cyclase activity ; GO:0004383'. xref: GO:0008074 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0055705 ! GCYA3_HUMAN relationship: location_of CCO:B0055706 ! GCYB1_HUMAN [Term] id: CCO:C0000527 name: voltage-gated potassium channel complex namespace: cellular_component def: "A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential." [GOC:mah] subset: gosubset_prok synonym: "voltage gated potassium channel complex" EXACT [] synonym: "voltage-dependent potassium channel complex" EXACT [] synonym: "voltage-sensitive potassium channel complex" EXACT [] xref: GO:0008076 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0001904 ! KCD11_HUMAN relationship: location_of CCO:B0005217 ! KCNRG_HUMAN relationship: location_of CCO:B0006271 ! BTBDA_HUMAN relationship: location_of CCO:B0043424 ! KCD17_HUMAN relationship: location_of CCO:B0049421 ! KCNQ1_HUMAN relationship: location_of CCO:B0054718 ! KCNK2_HUMAN relationship: location_of CCO:B0054741 ! KCNH1_HUMAN relationship: location_of CCO:B0055746 ! HME1_HUMAN relationship: location_of CCO:B0055844 ! KCNH2_HUMAN relationship: location_of CCO:B0057273 ! KCMB4_HUMAN relationship: location_of CCO:B0058049 ! KCD13_HUMAN relationship: location_of CCO:B0059273 ! KCNH4_HUMAN relationship: location_of CCO:B0062962 ! KCMB1_HUMAN relationship: location_of CCO:B0067282 ! KCD15_HUMAN-Phosphoserine35 relationship: location_of CCO:B0067285 ! KCIP2_HUMAN-Phosphotyrosine111 relationship: location_of CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 relationship: location_of CCO:B0071437 ! TNAP1_HUMAN-Phosphoserine280 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000528 name: light-activated voltage-gated calcium channel complex namespace: cellular_component def: "A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus." [GOC:mah, PMID:9223679] synonym: "light-activated voltage gated calcium channel complex" EXACT [] synonym: "light-activated voltage-dependent calcium channel complex" EXACT [] synonym: "light-activated voltage-sensitive calcium channel complex" EXACT [] xref: GO:0008087 is_a: CCO:C0000448 ! voltage-gated calcium channel complex [Term] id: CCO:C0000529 name: spectrin namespace: cellular_component def: "Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins." [http://cancerweb.ncl.ac.uk/] xref: GO:0008091 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001867 ! cell cortex part relationship: location_of CCO:B0014198 ! SPTB2_HUMAN-Phosphothreonine2195 relationship: location_of CCO:B0058894 ! SPTN5_HUMAN relationship: location_of CCO:B0070821 ! SPTA2_HUMAN-Phosphoserine1217 relationship: location_of CCO:B0070827 ! SPTB1_HUMAN-Phosphoserine2117 relationship: location_of CCO:B0070838 ! SPTN2_HUMAN-Phosphothreonine2354 relationship: location_of CCO:B0070840 ! SPTN4_HUMAN-Phosphothreonine2112 relationship: part_of CCO:C0001056 ! cortical actin cytoskeleton [Term] id: CCO:C0000530 name: signalosome namespace: cellular_component def: "A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome." [PMID:11019806, PMID:12186635, PMID:14570571] synonym: "COP9 complex" NARROW [] synonym: "CSN" EXACT [] xref: GO:0008180 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0006133 ! CSN6_HUMAN relationship: location_of CCO:B0006264 ! CSN7A_HUMAN relationship: location_of CCO:B0011360 ! CSN1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0011362 ! CSN5_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0022200 ! CSN4_HUMAN relationship: location_of CCO:B0030752 ! CSN3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0055605 ! CSN2_HUMAN relationship: location_of CCO:B0058795 ! NOD2_HUMAN [Term] id: CCO:C0000531 name: ecdysone receptor holocomplex namespace: cellular_component def: "A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes." [GOC:bf, PMID:14592980] xref: GO:0008230 is_a: CCO:C0000272 ! transcription factor complex is_a: CCO:C0001751 ! receptor complex [Term] id: CCO:C0000532 name: repressor ecdysone receptor complex namespace: cellular_component def: "A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes." [PMID:10488333] synonym: "repressor ecdysone receptor holocomplex" RELATED [] xref: GO:0008231 is_a: CCO:C0000531 ! ecdysone receptor holocomplex [Term] id: CCO:C0000533 name: activator ecdysone receptor complex namespace: cellular_component def: "A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes." [PMID:10488333] synonym: "activator ecdysone receptor holocomplex" RELATED [] xref: GO:0008232 is_a: CCO:C0000531 ! ecdysone receptor holocomplex [Term] id: CCO:C0000534 name: 2-acetyl-1-alkylglycerophosphocholine esterase complex namespace: cellular_component def: "An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF)." [GOC:jl, PMID:10542206, UniProtKB:Q28017] comment: See also the molecular function term '1-alkyl-2-acetylglycerophosphocholine esterase activity ; GO:0003847'. subset: gosubset_prok synonym: "1-alkyl-2-acetylglycerophosphocholine esterase complex" EXACT [] synonym: "platelet-activating factor acetylhydrolase complex" EXACT [] xref: GO:0008247 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000535 name: oligosaccharyl transferase complex namespace: cellular_component def: "A multisubunit protein complex in the endoplasmic reticulum membrane of eukaryotes that transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins; includes at least nine different subunits, at least in yeast." [ISBN:0879695595] synonym: "OST complex" EXACT [] xref: GO:0008250 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: location_of CCO:B0040688 ! RPN1_HUMAN relationship: location_of CCO:B0063449 ! STT3A_HUMAN relationship: location_of CCO:B0064624 ! DAD1_HUMAN-N-acetylserine2 relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0000536 name: gamma-tubulin ring complex namespace: cellular_component def: "A multiprotein complex composed of gamma-tubulin other non-tubulin proteins that forms a flexible open ring structure thought to be the unit of nucleation at the minus end of a microtubule." [GOC:clt, PMID:12134075] synonym: "gammaTuRC" EXACT [] xref: GO:0008274 is_a: CCO:C0000150 ! gamma-tubulin large complex relationship: location_of CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 [Term] id: CCO:C0000537 name: gamma-tubulin small complex namespace: cellular_component def: "A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex." [PMID:11297925, PMID:12134075] synonym: "gammaTuSC" EXACT [] xref: GO:0008275 is_a: CCO:C0000149 ! gamma-tubulin complex relationship: location_of CCO:B0005426 ! CENPJ_HUMAN [Term] id: CCO:C0000538 name: cohesin complex namespace: cellular_component def: "A protein complex required for sister chromatid cohesion in eukaryotes." [PMID:9887095] subset: goslim_pir synonym: "14S cohesin" NARROW [] synonym: "SMC complex" RELATED [] xref: GO:0008278 xref: GO:0008279 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: location_of CCO:B0064224 ! CDCA5_HUMAN-Phosphothreonine111 [Term] id: CCO:C0000539 name: cohesin core heterodimer namespace: cellular_component def: "The core heterodimer of a cohesin complex; a structure required for sister chromatid cohesion in eukaryotes." [GOC:jl] synonym: "9S cohesin" NARROW [] synonym: "Smc1-Smc3 complex" NARROW [] xref: GO:0008280 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0014070 ! SMC1A_HUMAN-Phosphoserine951 relationship: part_of CCO:C0000538 ! cohesin complex [Term] id: CCO:C0000540 name: ATP-sensitive potassium channel complex namespace: cellular_component def: "A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.2 subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SUR1 subunit stimulates channel activity." [PMID:16308567, PMID:16956886] xref: GO:0008282 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000541 name: protein serine/threonine phosphatase complex namespace: cellular_component def: "A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein." [GOC:bf] subset: goslim_pir subset: gosubset_prok xref: GO:0008287 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0001372 ! PPM1D_HUMAN relationship: location_of CCO:B0002123 ! ILKAP_HUMAN relationship: location_of CCO:B0013604 ! PPM1A_HUMAN-Phosphoserine377 relationship: location_of CCO:B0013606 ! PPM1G_HUMAN-Phosphoserine527 [Term] id: CCO:C0000542 name: F-actin capping protein complex namespace: cellular_component def: "A heterodimer consisting of alpha and a beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments." [GOC:go_curators, ISBN:0198599560] subset: goslim_pir xref: GO:0008290 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0006125 ! CAPZB_HUMAN relationship: location_of CCO:B0037556 ! CAZA3_HUMAN relationship: location_of CCO:B0039340 ! CAZA1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041285 ! CAZA2_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0055324 ! CAPG_HUMAN relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0000543 name: caspase complex namespace: cellular_component def: "A cytosolic endopeptidase with specificity for the hydrolysis of aspartyl bonds. Caspases are involved in apoptosis." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0008303 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0000544 name: integrin complex namespace: cellular_component def: "Any member of a family of heterodimeric transmembrane receptors for cell-adhesion molecules. The alpha and beta subunits are noncovalently bonded." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok synonym: "laminin receptor protein" RELATED [] xref: GO:0008305 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0006318 ! ITAE_HUMAN relationship: location_of CCO:B0026210 ! Q59FA8_HUMAN relationship: location_of CCO:B0026213 ! ITA8_HUMAN relationship: location_of CCO:B0026215 ! ITA2B_HUMAN relationship: location_of CCO:B0026216 ! Q17R67_HUMAN relationship: location_of CCO:B0026217 ! ITA5_HUMAN relationship: location_of CCO:B0026218 ! ITAV_HUMAN relationship: location_of CCO:B0033120 ! ITB5_HUMAN relationship: location_of CCO:B0033125 ! ITB8_HUMAN relationship: location_of CCO:B0033128 ! Q59FN1_HUMAN relationship: location_of CCO:B0033131 ! Q5T3E5_HUMAN relationship: location_of CCO:B0033132 ! Q59H50_HUMAN relationship: location_of CCO:B0033133 ! ITB6_HUMAN relationship: location_of CCO:B0033134 ! A8MYE6_HUMAN relationship: location_of CCO:B0033136 ! Q8WUM6_HUMAN relationship: location_of CCO:B0033137 ! ITB7_HUMAN relationship: location_of CCO:B0033141 ! ITB3_HUMAN relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0034889 ! ITB2_HUMAN-Phosphothreonine759 relationship: location_of CCO:B0034894 ! ITB4_HUMAN-Phosphoserine1084 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0050188 ! Q4VAK1_HUMAN relationship: location_of CCO:B0050189 ! ITAM_HUMAN relationship: location_of CCO:B0050190 ! ITAD_HUMAN relationship: location_of CCO:B0050191 ! ITA11_HUMAN relationship: location_of CCO:B0050192 ! ITAX_HUMAN relationship: location_of CCO:B0050193 ! Q59H14_HUMAN relationship: location_of CCO:B0050196 ! ITA2_HUMAN relationship: location_of CCO:B0050197 ! A8MPT3_HUMAN relationship: location_of CCO:B0050198 ! A8MTX2_HUMAN relationship: location_of CCO:B0050199 ! Q96HB1_HUMAN relationship: location_of CCO:B0050200 ! A8MZ95_HUMAN relationship: location_of CCO:B0050202 ! ITAL_HUMAN relationship: location_of CCO:B0054350 ! O14549_HUMAN relationship: location_of CCO:B0054652 ! ITA10_HUMAN relationship: location_of CCO:B0054809 ! ITGBL_HUMAN relationship: location_of CCO:B0055154 ! ITA6_HUMAN relationship: location_of CCO:B0055189 ! ITA3_HUMAN relationship: location_of CCO:B0055541 ! ITA1_HUMAN relationship: location_of CCO:B0055939 ! ITA7_HUMAN relationship: location_of CCO:B0055943 ! ITA9_HUMAN relationship: location_of CCO:B0056384 ! Q59F03_HUMAN relationship: location_of CCO:B0067159 ! ITA4_HUMAN-Phosphoserine1021 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000545 name: ionotropic glutamate receptor complex namespace: cellular_component def: "A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex." [http://www.bris.ac.uk/Depts/Synaptic/info/glutamate.html] xref: GO:0008328 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000546 name: katanin complex namespace: cellular_component def: "A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa)." [PMID:10910766] comment: Consider also annotating to the molecular function term 'microtubule-severing ATPase activity ; GO:0008568'. xref: GO:0008352 is_a: CCO:C0000435 ! microtubule associated complex is_a: CCO:C0001869 ! microtubule organizing center part relationship: location_of CCO:B0002100 ! KTNB1_HUMAN relationship: part_of CCO:C0000383 ! centrosome [Term] id: CCO:C0000547 name: IkappaB kinase complex namespace: cellular_component def: "A protein serine/threonine kinase that phosphorylates IkappaB, thereby targeting this for proteasomal degradation and allowing the nuclear translocation of kB. Composed of alpha, beta and gamma subunits, the latter not having kinase activity but presumed to play a regulatory role." [GOC:ma] synonym: "IKK complex" EXACT [] xref: GO:0008385 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0002228 ! ASC_HUMAN relationship: location_of CCO:B0018189 ! PYDC1_HUMAN relationship: location_of CCO:B0018761 ! M3K13_HUMAN relationship: location_of CCO:B0041164 ! NEMO_HUMAN-Phosphoserine43 relationship: location_of CCO:B0055216 ! PRDX3_HUMAN relationship: location_of CCO:B0069763 ! RB6I2_HUMAN-Phosphoserine17 [Term] id: CCO:C0000548 name: proteasome activator complex namespace: cellular_component def: "A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex." [GOC:rb] synonym: "PA28" NARROW [] xref: GO:0008537 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0006215 ! PSME1_HUMAN relationship: location_of CCO:B0041252 ! PSME3_HUMAN relationship: part_of CCO:C0002086 ! proteasome accessory complex [Term] id: CCO:C0000551 name: epsilon DNA polymerase complex namespace: cellular_component def: "A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair." [PMID:15814431, PMID:9745046] xref: GO:0008622 is_a: CCO:C0001651 ! DNA polymerase complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000003 ! nucleotide-excision repair complex relationship: part_of CCO:C0001798 ! nuclear replisome [Term] id: CCO:C0000552 name: chromatin accessibility complex namespace: cellular_component def: "A multisubunit complex that uses ATP to increase the general accessibility of DNA in chromatin. Unlike other known chromatin remodeling complexes, CHRAC can also function during chromatin assembly; it uses ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing." [GOC:bf, PMID:9252192] synonym: "CHRAC" EXACT [] synonym: "ISW2 complex" NARROW [] xref: GO:0008623 xref: GO:0016588 is_a: CCO:C0000806 ! chromatin remodeling complex [Term] id: CCO:C0000553 name: peptidoglycan-based cell wall namespace: cellular_component def: "A protective structure outside the cytoplasmic membrane composed of peptidoglycan, a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids; also called murein. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2)." [GOC:mlg, ISBN:0815108893] subset: gosubset_prok synonym: "cell wall (sensu Bacteria)" EXACT [] synonym: "envelope (sensu Bacteria)" BROAD [] synonym: "murein sacculus" RELATED [] synonym: "peptidoglycan" NARROW [] xref: GO:0009274 is_a: CCO:C0000239 ! cell wall [Term] id: CCO:C0000557 name: cell outer membrane namespace: cellular_component def: "A lipid bilayer that forms the outermost layer of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures." [GOC:mtg_sensu, ISBN:0135712254] subset: gosubset_prok synonym: "outer membrane (sensu Gram-negative Bacteria)" EXACT [] synonym: "outer membrane (sensu Proteobacteria)" EXACT [] synonym: "outer membrane of cell" EXACT [] xref: GO:0009279 is_a: CCO:C0000898 ! outer membrane is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0001000 ! cell envelope [Term] id: CCO:C0000561 name: flagellin-based flagellum namespace: cellular_component def: "A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope." [GOC:jh2, GOC:mtg_sensu, PMID:7787060] subset: gosubset_prok synonym: "flagellum (sensu Bacteria)" EXACT [] xref: GO:0009288 is_a: CCO:C0000896 ! flagellum relationship: location_of CCO:B0055564 ! CABP4_HUMAN [Term] id: CCO:C0000562 name: fimbrium namespace: cellular_component def: "A proteinaceous hair-like appendage on the surface of bacteria; range from 2-8 nm in diameter." [ISBN:0598034692] subset: goslim_pir subset: gosubset_prok synonym: "fimbria" BROAD [] synonym: "fimbriae" EXACT [] synonym: "pilus" BROAD [] xref: GO:0009289 is_a: CCO:C0001706 ! cell projection [Term] id: CCO:C0000563 name: nucleoid namespace: cellular_component def: "The region of a bacterial cell, mitochondrion or chloroplast to which the DNA is confined." [GOC:ma, ISBN:3540076689] subset: gosubset_prok xref: GO:0009295 is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000564 name: 3-isopropylmalate dehydratase complex namespace: cellular_component def: "A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate." [BRENDA:4.2.1.33, GOC:jl, UniProtKB:Q8TW31] comment: See also the molecular function term '3-isopropylmalate dehydratase activity ; GO:0003861'. subset: gosubset_prok synonym: "isopropylmalate isomerase complex" EXACT [] xref: GO:0009316 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0000565 name: acetyl-CoA carboxylase complex namespace: cellular_component def: "A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex." [GOC:jl, GOC:mah, UniProtKB:P24182] subset: goslim_pir subset: gosubset_prok synonym: "ACCase complex" EXACT [] xref: GO:0009317 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000566 name: exodeoxyribonuclease VII complex namespace: cellular_component def: "An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA." [EC:3.1.11.6] subset: gosubset_prok xref: GO:0009318 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000567 name: cytochrome o ubiquinol oxidase complex namespace: cellular_component def: "A bacterial heterooctameric enzyme composed of two A chains, two B chains, two C chains and two D chains. Possesses cytochrome o ubiquinol oxidase activity." [GOC:jl, UniProtKB:P0ABJ3] comment: See also the molecular function term 'cytochrome o ubiquinol oxidase activity ; GO:0008827'. subset: gosubset_prok xref: GO:0009319 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0000767 ! integral to membrane [Term] id: CCO:C0000568 name: phosphoribosylaminoimidazole carboxylase complex namespace: cellular_component def: "A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity." [GOC:mah] comment: See also the molecular function term 'phosphoribosylaminoimidazole carboxylase activity ; GO:0004638'. subset: gosubset_prok xref: GO:0009320 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0069635 ! PUR6_HUMAN-Phosphoserine27 [Term] id: CCO:C0000569 name: alkyl hydroperoxide reductase complex namespace: cellular_component def: "An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides." [BRENDA:1.11.1.15, GOC:jl, UniProtKB:P0A0B5] comment: See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'. xref: GO:0009321 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000570 name: trimethylamine-N-oxide reductase complex namespace: cellular_component def: "An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine." [EC:1.6.6.9] subset: gosubset_prok xref: GO:0009322 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000571 name: ribosomal-protein-alanine N-acetyltransferase complex namespace: cellular_component def: "An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine." [EC:2.3.1.128] xref: GO:0009323 is_a: CCO:C0001169 ! protein acetyltransferase complex [Term] id: CCO:C0000572 name: D-amino-acid dehydrogenase complex namespace: cellular_component def: "A protein complex that possesses D-amino-acid dehydrogenase activity." [GOC:mah] comment: See also the molecular function term 'D-amino-acid oxidase activity ; GO:0003884'. subset: gosubset_prok xref: GO:0009324 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0000573 name: nitrate reductase complex namespace: cellular_component def: "An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor." [EC:1.7.99.4] subset: gosubset_prok xref: GO:0009325 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000574 name: formate dehydrogenase complex namespace: cellular_component def: "An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2)." [EC:1.2.1.2] subset: gosubset_prok xref: GO:0009326 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000575 name: NAD(P)+ transhydrogenase complex (AB-specific) namespace: cellular_component def: "A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified." [BRENDA:1.6.1.2, GOC:mah] xref: GO:0009327 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000576 name: phenylalanine-tRNA ligase complex namespace: cellular_component def: "An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe)." [EC:6.1.1.20] subset: gosubset_prok xref: GO:0009328 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000577 name: acetate CoA-transferase complex namespace: cellular_component def: "A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA." [GOC:jl, UniProtKB:P08193] xref: GO:0009329 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0000565 ! acetyl-CoA carboxylase complex [Term] id: CCO:C0000578 name: DNA topoisomerase complex (ATP-hydrolyzing) namespace: cellular_component def: "Complex that possesses DNA topoisomerase (ATP-hydrolyzing) activity." [GOC:mah] comment: See also the molecular function term 'DNA topoisomerase (ATP-hydrolyzing) activity ; GO:0003918'. subset: gosubset_prok xref: GO:0009330 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 [Term] id: CCO:C0000579 name: glycerol-3-phosphate dehydrogenase complex namespace: cellular_component def: "An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate." [EC:1.1.99.5] subset: gosubset_prok xref: GO:0009331 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0006143 ! GPDA_HUMAN [Term] id: CCO:C0000580 name: glutamate-tRNA ligase complex namespace: cellular_component def: "An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu)." [EC:6.1.1.17] xref: GO:0009332 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000581 name: cysteine synthase complex namespace: cellular_component def: "Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A." [EC:4.2.99.8, MetaCyc:CYSSYNMULTI-CPLX] xref: GO:0009333 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000582 name: 3-phenylpropionate dioxygenase complex namespace: cellular_component def: "Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol)." [GOC:jl, UniProtKB:P77650] comment: See also the molecular function term '3-phenylpropionate dioxygenase activity ; GO:0008695'. xref: GO:0009334 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000583 name: sulfate adenylyltransferase complex (ATP) namespace: cellular_component def: "An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP." [EC:2.7.7.4] synonym: "sulphate adenylyltransferase complex (ATP)" EXACT [] xref: GO:0009336 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000584 name: sulfite reductase complex (NADPH) namespace: cellular_component def: "A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of hydrogen sulfide to sulfide." [BRENDA:1.8.1.2, GOC:jl] comment: See also the molecular function term 'sulfite reductase (NADPH) activity ; GO:0004783'. subset: gosubset_prok synonym: "sulphite reductase complex (NADPH)" EXACT [] xref: GO:0009337 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000585 name: exodeoxyribonuclease V complex namespace: cellular_component def: "An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA." [EC:3.1.11.5] subset: gosubset_prok xref: GO:0009338 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000586 name: glycolate oxidase complex namespace: cellular_component def: "An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN)." [EC:1.1.3.15] subset: gosubset_prok xref: GO:0009339 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000587 name: DNA topoisomerase IV complex namespace: cellular_component def: "A heterodimeric enzyme, which in most bacterial species is composed of two subunits, PARC and PARE. Functions in chromosome segregation and can relax supercoiled DNA." [GOC:jl, UniProtKB:Q45066] subset: gosubset_prok xref: GO:0009340 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000588 name: beta-galactosidase complex namespace: cellular_component def: "A multimeric enzyme complex that in E. coli is an heterooctamer made up of four alpha subunits and four beta subunits. Catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides." [EC:3.2.1.23, UniProtKB:P06864] subset: gosubset_prok xref: GO:0009341 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000589 name: glutamate synthase complex (NADPH) namespace: cellular_component def: "A complex that possesses glutamate synthase (NADPH) activity." [EC:1.4.1.13, GOC:mah] subset: gosubset_prok xref: GO:0009342 is_a: CCO:C0001114 ! glutamate synthase complex [Term] id: CCO:C0000590 name: biotin carboxylase complex namespace: cellular_component def: "An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2)." [EC:6.3.4.14] subset: gosubset_prok xref: GO:0009343 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0000565 ! acetyl-CoA carboxylase complex [Term] id: CCO:C0000591 name: nitrite reductase complex [NAD(P)H] namespace: cellular_component def: "Complex that possesses nitrite reductase [NAD(P)H] activity." [GOC:mah] comment: See also the molecular function term 'nitrite reductase [NAD(P)H] activity ; GO:0008942'. xref: GO:0009344 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000592 name: glycine-tRNA ligase complex namespace: cellular_component def: "A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly)." [EC:6.1.1.14, GOC:jl, UniProtKB:Q10039, UniProtKB:Q8YVJ2] subset: gosubset_prok synonym: "glycine-tRNA synthetase complex" EXACT [] xref: GO:0009345 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000593 name: citrate lyase complex namespace: cellular_component def: "Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity." [EC:4.1.3.6, MetaCyc:ACECITLY-CPLX] subset: gosubset_prok xref: GO:0009346 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000594 name: aspartate carbamoyltransferase complex namespace: cellular_component def: "A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides." [PMID:10447693] comment: Note that in eukaryotes, aspartate carbamoyltransferase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term. subset: gosubset_prok xref: GO:0009347 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000595 name: ornithine carbamoyltransferase complex namespace: cellular_component def: "An enzyme complex that catalyzes the transfer of a carbamoyl to ornithine, forming citrulline." [EC:2.1.3.3] subset: gosubset_prok xref: GO:0009348 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000596 name: riboflavin synthase complex namespace: cellular_component def: "An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine." [EC:2.5.1.9] subset: gosubset_prok xref: GO:0009349 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000597 name: ethanolamine ammonia-lyase complex namespace: cellular_component def: "An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia." [EC:4.3.1.7] xref: GO:0009350 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000598 name: mitochondrial oxoglutarate dehydrogenase complex namespace: cellular_component def: "A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix." [GOC:mtg_sensu, UniProtKB:Q60597] comment: See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'. synonym: "oxoglutarate dehydrogenase complex (sensu Eukaryota)" EXACT [] xref: GO:0009353 is_a: CCO:C0001848 ! mitochondrial part is_a: CCO:C0001915 ! oxoglutarate dehydrogenase complex relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000599 name: DNA polymerase V complex namespace: cellular_component def: "A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis." [PMID:10430871, PMID:10542196] xref: GO:0009355 is_a: CCO:C0001651 ! DNA polymerase complex [Term] id: CCO:C0000600 name: aminodeoxychorismate synthase complex namespace: cellular_component def: "A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity." [PMID:2251281, PMID:7592344] synonym: "4-amino-4-deoxychorismate synthase complex" RELATED [] synonym: "ADC synthase complex" EXACT [] synonym: "p-aminobenzoate synthetase complex" RELATED [] xref: GO:0009356 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000601 name: protein-N(PI)-phosphohistidine-sugar phosphotransferase complex namespace: cellular_component def: "An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system." [EC:2.7.1.69] xref: GO:0009357 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000602 name: polyphosphate kinase complex namespace: cellular_component def: "A protein complex that possesses polyphosphate kinase activity." [GOC:mah] comment: See also the molecular function term 'polyphosphate kinase activity ; GO:0008976'. subset: gosubset_prok xref: GO:0009358 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000603 name: Type II site-specific deoxyribonuclease complex namespace: cellular_component def: "A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell." [PMID:12654995] subset: gosubset_prok synonym: "Type II restriction enzyme complex" EXACT [] xref: GO:0009359 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000604 name: DNA polymerase III complex namespace: cellular_component def: "A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands." [PMID:11525729, PMID:12940977] subset: gosubset_prok xref: GO:0009360 is_a: CCO:C0001651 ! DNA polymerase complex [Term] id: CCO:C0000605 name: succinate-CoA ligase complex (ADP-forming) namespace: cellular_component def: "A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP." [EC:6.2.1.5, GOC:jl] subset: gosubset_prok xref: GO:0009361 is_a: CCO:C0001687 ! succinate-CoA ligase complex [Term] id: CCO:C0000606 name: protein histidine kinase complex namespace: cellular_component def: "A complex that possesses protein histidine kinase activity." [GOC:mah] xref: GO:0009365 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000607 name: enterobactin synthetase complex namespace: cellular_component def: "A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway." [UniProtKB:P15048] subset: gosubset_prok synonym: "enterochelin synthetase complex" EXACT [] xref: GO:0009366 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000608 name: prepilin peptidase complex namespace: cellular_component def: "An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group." [EC:3.4.23.43] xref: GO:0009367 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part [Term] id: CCO:C0000609 name: endopeptidase Clp complex namespace: cellular_component def: "An enzymatically active or inactive multimeric complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits." [PMID:11352464] subset: goslim_pir subset: gosubset_prok xref: GO:0009368 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000610 name: ferredoxin hydrogenase complex namespace: cellular_component def: "An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances." [EC:1.12.7.2] subset: gosubset_prok synonym: "hydrogenase complex" BROAD [] xref: GO:0009375 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000611 name: HslUV protease complex namespace: cellular_component def: "A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other Clp family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, six identical subunits of both the ATPase, ClpY, and the protease, ClpQ, self-assemble into an oligomeric ring, and two rings of each subunit, two ClpQ rings surrounded by single ClpY rings, form a dumbbell-shaped complex." [PMID:12670962] subset: gosubset_prok synonym: "ClpYQ protease complex" EXACT [] xref: GO:0009376 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000612 name: Holliday junction helicase complex namespace: cellular_component def: "A DNA helicase complex that forms part of a Holliday junction resolvase complex, where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA ." [PMID:16935884, PMID:9442895] subset: gosubset_prok xref: GO:0009379 is_a: CCO:C0001555 ! DNA helicase complex relationship: part_of CCO:C0001998 ! Holliday junction resolvase complex [Term] id: CCO:C0000613 name: excinuclease repair complex namespace: cellular_component def: "Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and one B subunit bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between subunit B and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap." [GOC:mah, GOC:mlg, PMID:15192705] subset: gosubset_prok synonym: "excinuclease ABC complex" EXACT [] synonym: "UvrABC excinuclease complex" EXACT [] xref: GO:0009380 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000614 name: imidazoleglycerol-phosphate synthase complex namespace: cellular_component def: "Complex that possesses imidazoleglycerol-phosphate synthase activity." [GOC:mah] comment: See also the molecular function term 'imidazoleglycerol-phosphate synthase activity ; GO:0000107'. subset: gosubset_prok synonym: "imidazoleglycerol phosphate synthase complex" EXACT [] xref: GO:0009382 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000615 name: dimethyl sulfoxide reductase complex namespace: cellular_component def: "An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide." [UM-BBD_enzymeID:e0188] synonym: "dimethyl sulphoxide reductase complex" EXACT [] xref: GO:0009390 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000616 name: fimbrial shaft namespace: cellular_component def: "The long, slender, mid section of a fimbrium." [GOC:jl] subset: gosubset_prok xref: GO:0009418 is_a: CCO:C0001862 ! fimbrial part [Term] id: CCO:C0000617 name: fimbrial tip namespace: cellular_component def: "The pointed extremity furthest from the cell of a fimbrium." [GOC:jl] subset: gosubset_prok xref: GO:0009419 is_a: CCO:C0001862 ! fimbrial part [Term] id: CCO:C0000622 name: flagellin-based flagellum basal body namespace: cellular_component def: "One of the three major substructures of the flagellin-based flagellum; a structure consisting of a rod, a series of rings, the Mot proteins, the switch complex and the flagellum-specific export apparatus. The rings anchor the flagellum to the cytoplasmic membrane (MS ring), the peptidoglycan (P ring) and the outer membrane (L ring)." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body (sensu Bacteria)" EXACT [] xref: GO:0009425 is_a: CCO:C0001879 ! flagellin-based flagellum part [Term] id: CCO:C0000629 name: microtubule-based flagellum namespace: cellular_component def: "A long, whiplike protrusion from the surface of a eukaryotic cell, whose undulations drive the cell through a liquid medium; similar in structure to a cilium. The flagellum is based on a 9+2 arrangement of microtubules." [GOC:mtg_sensu, ISBN:0815316194] comment: See also the cellular component term 'cilium ; GO:0005929'. synonym: "flagellum (sensu Eukaryota)" EXACT [] xref: GO:0009434 is_a: CCO:C0000896 ! flagellum is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0054351 ! G3PT_HUMAN relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0065533 ! AKAP3_HUMAN-Phosphoserine612 relationship: location_of CCO:B0065551 ! AKAP4_HUMAN-Phosphoserine492 [Term] id: CCO:C0000630 name: amyloplast namespace: cellular_component def: "A plastid whose main function is to synthesize and store starch." [ISBN:0140514031] xref: GO:0009501 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000632 name: thylakoid light-harvesting complex namespace: cellular_component def: "A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. As in, but not restricted to, green plants and algae (Viridiplantae, ncbi_taxonomy_id:33090)." [GOC:mtg_sensu, ISBN:0198547684] synonym: "light-harvesting complex (sensu Viridiplantae)" EXACT [] xref: GO:0009503 is_a: CCO:C0000943 ! light-harvesting complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000663 ! chloroplast thylakoid membrane [Term] id: CCO:C0000633 name: cell plate namespace: cellular_component def: "The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells." [ISBN:0198547684] xref: GO:0009504 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000635 name: plasmodesma namespace: cellular_component def: "A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "plasmodesmata" EXACT [] xref: GO:0009506 is_a: CCO:C0000463 ! intercellular junction relationship: part_of CCO:C0002026 ! symplast [Term] id: CCO:C0000636 name: chloroplast namespace: cellular_component def: "A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma." [ISBN:0471245208] xref: GO:0009507 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000637 name: plastid chromosome namespace: cellular_component def: "A circular DNA molecule containing plastid encoded genes." [ISBN:0943883999] xref: GO:0009508 is_a: CCO:C0000041 ! cytoplasmic chromosome is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0001679 ! plastid nucleoid [Term] id: CCO:C0000638 name: chromoplast namespace: cellular_component def: "A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments." [ISBN:0471245208] xref: GO:0009509 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000639 name: plasmodesmatal desmotubule namespace: cellular_component def: "A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell." [http://biology.kenyon.edu/edwards/project/greg/pd.htm] synonym: "desmotubule central rod" RELATED [] xref: GO:0009510 xref: GO:0009572 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000635 ! plasmodesma [Term] id: CCO:C0000640 name: plasmodesmatal endoplasmic reticulum namespace: cellular_component def: "Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells." [GOC:ai] synonym: "plasmodesmatal ER" EXACT [] xref: GO:0009511 is_a: CCO:C0000364 ! endoplasmic reticulum is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000639 ! plasmodesmatal desmotubule [Term] id: CCO:C0000641 name: cytochrome b6f complex namespace: cellular_component def: "Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species." [ISBN:0943883999, PMID:16228398, PMID:16352458] subset: gosubset_prok synonym: "cyt b(6)f complex" EXACT [] synonym: "cyt b6-f complex" EXACT [] synonym: "cyt b6/f complex" EXACT [] synonym: "cyt b6f complex" EXACT [] synonym: "cytochrome b(6)f complex" EXACT [] synonym: "cytochrome b6-f complex" EXACT [] synonym: "cytochrome b6/f complex" EXACT [] xref: GO:0009512 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001855 ! thylakoid part [Term] id: CCO:C0000642 name: etioplast namespace: cellular_component def: "A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions." [ISBN:0943883999] xref: GO:0009513 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000643 name: glyoxysome namespace: cellular_component def: "A microbody that contains the enzymes of the glyoxylate pathway." [ISBN:0140514031] xref: GO:0009514 is_a: CCO:C0001652 ! microbody [Term] id: CCO:C0000644 name: granal stacked thylakoid namespace: cellular_component def: "Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II." [GOC:lr] synonym: "chloroplast stacked thylakoid" EXACT [] xref: GO:0009515 is_a: CCO:C0000662 ! chloroplast thylakoid relationship: part_of CCO:C0000669 ! granum [Term] id: CCO:C0000645 name: leucoplast namespace: cellular_component def: "Colorless plastid involved in the synthesis of monoterpenes." [ISBN:0943883999] xref: GO:0009516 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000646 name: PSII associated light-harvesting complex II namespace: cellular_component def: "Protein-pigment complex associated with photosystem II." [GOC:lr, ISBN:0582227089] synonym: "LHCII" EXACT [] xref: GO:0009517 is_a: CCO:C0000632 ! thylakoid light-harvesting complex [Term] id: CCO:C0000647 name: PSI associated light-harvesting complex I namespace: cellular_component def: "Protein-pigment complex associated with photosystem I." [GOC:lr] synonym: "LHCI" EXACT [] xref: GO:0009518 is_a: CCO:C0000632 ! thylakoid light-harvesting complex [Term] id: CCO:C0000648 name: middle lamella namespace: cellular_component def: "Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells." [ISBN:0471245208] xref: GO:0009519 is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0000649 name: photosystem namespace: cellular_component def: "A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers." [GOC:ds, GOC:mah, ISBN:0140514031, PMID:9821949] subset: goslim_pir subset: gosubset_prok synonym: "reaction center (sensu Gram-negative Bacteria)" NARROW [] synonym: "reaction center (sensu Proteobacteria)" NARROW [] synonym: "reaction centre (sensu Gram-negative Bacteria)" NARROW [] synonym: "reaction centre (sensu Proteobacteria)" NARROW [] xref: GO:0009521 xref: GO:0030090 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0002137 ! photosynthetic membrane [Term] id: CCO:C0000650 name: photosystem I namespace: cellular_component def: "A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation)." [GOC:ds, GOC:mah, ISBN:0140514031, PMID:9821949] subset: gosubset_prok xref: GO:0009522 is_a: CCO:C0000649 ! photosystem [Term] id: CCO:C0000651 name: photosystem II namespace: cellular_component def: "A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center." [GOC:ds, GOC:mah, ISBN:0943088399, PMID:9821949] subset: gosubset_prok xref: GO:0009523 is_a: CCO:C0000649 ! photosystem [Term] id: CCO:C0000652 name: phragmoplast namespace: cellular_component def: "Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules." [ISBN:0471245208] xref: GO:0009524 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000653 name: phragmosome namespace: cellular_component def: "A flattened membranous vesicle containing cell wall components." [ISBN:0943883999] xref: GO:0009525 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000654 name: plastid envelope namespace: cellular_component def: "The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:jy] xref: GO:0009526 is_a: CCO:C0001360 ! organelle envelope is_a: CCO:C0001854 ! plastid part [Term] id: CCO:C0000655 name: plastid outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope." [GOC:lr] xref: GO:0009527 is_a: CCO:C0001361 ! organelle outer membrane is_a: CCO:C0001634 ! plastid membrane [Term] id: CCO:C0000656 name: plastid inner membrane namespace: cellular_component def: "The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma." [GOC:lr] xref: GO:0009528 is_a: CCO:C0000897 ! organelle inner membrane is_a: CCO:C0001634 ! plastid membrane [Term] id: CCO:C0000657 name: plastid intermembrane space namespace: cellular_component def: "The region between the inner and outer lipid bilayers of the plastid envelope." [GOC:lr] synonym: "plastid envelope lumen" EXACT [] xref: GO:0009529 is_a: CCO:C0001363 ! organelle envelope lumen is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000654 ! plastid envelope [Term] id: CCO:C0000658 name: primary cell wall namespace: cellular_component def: "A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present." [GOC:jic, http://cancerweb.ncl.ac.uk] xref: GO:0009530 is_a: CCO:C0001985 ! middle lamella-containing extracellular matrix is_a: CCO:C0002158 ! plant-type cell wall [Term] id: CCO:C0000659 name: secondary cell wall namespace: cellular_component def: "A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin." [GOC:jic, http://cancerweb.ncl.ac.uk] xref: GO:0009531 is_a: CCO:C0001985 ! middle lamella-containing extracellular matrix is_a: CCO:C0002158 ! plant-type cell wall [Term] id: CCO:C0000660 name: plastid stroma namespace: cellular_component def: "The proteinaceous ground substance of plastids." [ISBN:047142520] xref: GO:0009532 is_a: CCO:C0001854 ! plastid part [Term] id: CCO:C0000661 name: chloroplast stromal thylakoid namespace: cellular_component def: "Unstacked thylakoids that connect the grana stacks through the stroma." [ISBN:0943883999] xref: GO:0009533 is_a: CCO:C0000662 ! chloroplast thylakoid relationship: part_of CCO:C0000681 ! chloroplast stroma [Term] id: CCO:C0000662 name: chloroplast thylakoid namespace: cellular_component def: "Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana." [GOC:mtg_sensu, ISBN:0943883999] synonym: "thylakoid (sensu Viridiplantae)" EXACT [] xref: GO:0009534 is_a: CCO:C0001368 ! plastid thylakoid is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000663 name: chloroplast thylakoid membrane namespace: cellular_component def: "The pigmented membrane of a chloroplast thylakoid." [GOC:lr, GOC:mtg_sensu] synonym: "thylakoid membrane (sensu Viridiplantae)" EXACT [] xref: GO:0009535 is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0002020 ! plastid thylakoid membrane relationship: part_of CCO:C0000662 ! chloroplast thylakoid [Term] id: CCO:C0000664 name: plastid namespace: cellular_component def: "Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid." [GOC:jl, ISBN:0198547684] subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: gosubset_prok xref: GO:0009536 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0000665 name: proplastid namespace: cellular_component def: "The precursor of other plastids." [ISBN:0943883999] xref: GO:0009537 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000666 name: photosystem I reaction center namespace: cellular_component def: "A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin." [GOC:kd, ISBN:0943088399] subset: gosubset_prok synonym: "photosystem I reaction centre" EXACT [] xref: GO:0009538 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000650 ! photosystem I [Term] id: CCO:C0000667 name: photosystem II reaction center namespace: cellular_component def: "An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone." [GOC:kd, ISBN:0943088399] subset: gosubset_prok synonym: "photosystem II reaction centre" EXACT [] xref: GO:0009539 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000651 ! photosystem II [Term] id: CCO:C0000668 name: etioplast prolamellar body namespace: cellular_component def: "A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast." [ISBN:0140514031] xref: GO:0009541 is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000642 ! etioplast [Term] id: CCO:C0000669 name: granum namespace: cellular_component def: "Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis." [ISBN:014051403] xref: GO:0009542 is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000670 name: chloroplast thylakoid lumen namespace: cellular_component def: "The cavity enclosed within the chloroplast thylakoid membrane." [GOC:mtg_sensu, ISBN:006501037] synonym: "thylakoid lumen (sensu Viridiplantae)" EXACT [] xref: GO:0009543 is_a: CCO:C0001370 ! plastid thylakoid lumen is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000662 ! chloroplast thylakoid [Term] id: CCO:C0000671 name: chloroplast ATP synthase complex namespace: cellular_component def: "The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts." [ISBN:019854768] xref: GO:0009544 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000663 ! chloroplast thylakoid membrane [Term] id: CCO:C0000672 name: elaioplast namespace: cellular_component def: "A leucoplast in which oil is stored." [ISBN:0140514031] xref: GO:0009545 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000673 name: plasmodesmatal cytoplasmic sleeve namespace: cellular_component def: "The space between the plasma membrane and the desmotubule of a plasmodesma." [http://biology.kenyon.edu/edwards/project/greg/pd.htm] synonym: "plasmodesmatal cytoplasmic annulus" EXACT [] xref: GO:0009546 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000635 ! plasmodesma [Term] id: CCO:C0000674 name: plastid ribosome namespace: cellular_component def: "A ribosome contained within a plastid." [GOC:tair_curators] xref: GO:0009547 is_a: CCO:C0000057 ! organellar ribosome is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000660 ! plastid stroma [Term] id: CCO:C0000675 name: plasmodesmatal plasma membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a plasmodesma." [GOC:mah] xref: GO:0009548 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000635 ! plasmodesma [Term] id: CCO:C0000676 name: cellulose microfibril namespace: cellular_component def: "Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls where it is found as microfibrils laid down in orthogonal layers. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the protoplast." [GOC:jic, http://cancerweb.ncl.ac.uk, ISBN:0943088399] xref: GO:0009549 is_a: CCO:C0000169 ! microfibril is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0000658 ! primary cell wall relationship: part_of CCO:C0000659 ! secondary cell wall [Term] id: CCO:C0000677 name: primary plasmodesma namespace: cellular_component def: "A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis." [PMID:15012255] synonym: "simple plasmodesma" EXACT [] xref: GO:0009550 is_a: CCO:C0000635 ! plasmodesma [Term] id: CCO:C0000678 name: secondary plasmodesma namespace: cellular_component def: "A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata." [PMID:15012255] xref: GO:0009551 is_a: CCO:C0000635 ! plasmodesma [Term] id: CCO:C0000679 name: amyloplast starch grain namespace: cellular_component def: "Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped." [GOC:jl, PMID:11217978] synonym: "amyloplast starch granule" EXACT [] xref: GO:0009568 is_a: CCO:C0001712 ! starch grain relationship: part_of CCO:C0000630 ! amyloplast [Term] id: CCO:C0000680 name: chloroplast starch grain namespace: cellular_component def: "Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "chloroplast starch granule" EXACT [] xref: GO:0009569 is_a: CCO:C0001712 ! starch grain is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000681 name: chloroplast stroma namespace: cellular_component def: "The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis." [ISBN:0198547684] xref: GO:0009570 is_a: CCO:C0000660 ! plastid stroma is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000682 name: proplastid stroma namespace: cellular_component def: "The space enclosed by the double membrane of a proplastid." [GOC:jl] xref: GO:0009571 is_a: CCO:C0000660 ! plastid stroma relationship: part_of CCO:C0000665 ! proplastid [Term] id: CCO:C0000683 name: chloroplast ribulose bisphosphate carboxylase complex namespace: cellular_component def: "A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate." [GOC:mlg, GOC:mtg_sensu] synonym: "ribulose bisphosphate carboxylase complex (sensu Magnoliophyta)" EXACT [] synonym: "RubisCO complex (sensu Magnoliophyta)" EXACT [] xref: GO:0009573 is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001999 ! ribulose bisphosphate carboxylase complex relationship: part_of CCO:C0000681 ! chloroplast stroma [Term] id: CCO:C0000684 name: preprophase band namespace: cellular_component def: "A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0009574 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000685 name: chromoplast stroma namespace: cellular_component def: "The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material." [GOC:jl] xref: GO:0009575 is_a: CCO:C0000660 ! plastid stroma relationship: part_of CCO:C0000638 ! chromoplast [Term] id: CCO:C0000686 name: leucoplast stroma namespace: cellular_component def: "The space enclosed by the double membrane of a leucoplast." [GOC:mah] xref: GO:0009576 is_a: CCO:C0000660 ! plastid stroma relationship: part_of CCO:C0000645 ! leucoplast [Term] id: CCO:C0000687 name: elaioplast stroma namespace: cellular_component def: "The space enclosed by the double membrane of an elaioplast." [GOC:mah] xref: GO:0009577 is_a: CCO:C0000660 ! plastid stroma relationship: part_of CCO:C0000672 ! elaioplast [Term] id: CCO:C0000688 name: etioplast stroma namespace: cellular_component def: "The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA." [GOC:jl] xref: GO:0009578 is_a: CCO:C0000660 ! plastid stroma relationship: part_of CCO:C0000642 ! etioplast [Term] id: CCO:C0000689 name: thylakoid namespace: cellular_component def: "A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation." [GOC:ds, GOC:mtg_sensu, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: gosubset_prok synonym: "photosynthetic membrane" RELATED [] xref: GO:0009579 is_a: CCO:C0002137 ! photosynthetic membrane [Term] id: CCO:C0000690 name: oxygen evolving complex namespace: cellular_component def: "A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ)." [InterPro:IPR002683] subset: gosubset_prok xref: GO:0009654 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000651 ! photosystem II [Term] id: CCO:C0000691 name: PSII associated light-harvesting complex II, core complex namespace: cellular_component def: "The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center." [GOC:lr] subset: gosubset_prok synonym: "PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex" NARROW [] synonym: "PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex" NARROW [] synonym: "PSII associated light-harvesting complex II, core complex, LHCIId subcomplex" NARROW [] xref: GO:0009655 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000646 ! PSII associated light-harvesting complex II [Term] id: CCO:C0000692 name: PSII associated light-harvesting complex II, peripheral complex namespace: cellular_component def: "Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light." [GOC:lr] subset: gosubset_prok xref: GO:0009656 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000646 ! PSII associated light-harvesting complex II [Term] id: CCO:C0000694 name: chloroplast inner membrane namespace: cellular_component def: "The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma." [GOC:tb] synonym: "chloroplast inner envelope" EXACT [] xref: GO:0009706 is_a: CCO:C0000656 ! plastid inner membrane is_a: CCO:C0001362 ! chloroplast membrane [Term] id: CCO:C0000695 name: chloroplast outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope." [GOC:tb] synonym: "chloroplast outer envelope" EXACT [] xref: GO:0009707 is_a: CCO:C0000655 ! plastid outer membrane is_a: CCO:C0001362 ! chloroplast membrane [Term] id: CCO:C0000696 name: photosystem I antenna complex namespace: cellular_component def: "The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs)." [GOC:jic, ISBN:0716731363] xref: GO:0009782 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000650 ! photosystem I [Term] id: CCO:C0000697 name: photosystem II antenna complex namespace: cellular_component def: "The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs)." [GOC:jic, ISBN:0716731363] xref: GO:0009783 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000651 ! photosystem II [Term] id: CCO:C0000698 name: chloroplastic endopeptidase Clp complex namespace: cellular_component def: "A Clp endopeptidase complex located in the chloroplast." [GOC:mah] xref: GO:0009840 is_a: CCO:C0000609 ! endopeptidase Clp complex is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000681 ! chloroplast stroma [Term] id: CCO:C0000699 name: mitochondrial endopeptidase Clp complex namespace: cellular_component def: "A Clp endopeptidase complex located in the mitochondrion." [GOC:mah] xref: GO:0009841 is_a: CCO:C0000609 ! endopeptidase Clp complex is_a: CCO:C0001848 ! mitochondrial part relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000700 name: cyanelle namespace: cellular_component def: "Plastid type found in Glaucophyta having unstacked thylakoid membranes bearing phycobilisomes; cyanelles are bound by a double membrane and a peptidoglycan layer." [ISBN:052131687] subset: gosubset_prok xref: GO:0009842 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000701 name: cyanelle thylakoid namespace: cellular_component def: "Photosynthetic membrane resembling that of cyanobacteria found in the cyanelles of certain algae." [GOC:lr, GOC:mtg_sensu] subset: gosubset_prok synonym: "thylakoid (sensu Glaucocystophyceae)" EXACT [] xref: GO:0009843 is_a: CCO:C0001368 ! plastid thylakoid relationship: part_of CCO:C0000700 ! cyanelle [Term] id: CCO:C0000702 name: external side of plasma membrane namespace: cellular_component def: "The side of the plasma membrane that is opposite to the side that faces the cytoplasm." [GOC:tb] subset: gosubset_prok synonym: "juxtamembrane" BROAD [] synonym: "outer surface of cytoplasmic membrane" EXACT [] xref: GO:0009897 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0005450 ! ICAM1_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005740 ! CD4_HUMAN relationship: location_of CCO:B0006345 ! CATB_HUMAN relationship: location_of CCO:B0011014 ! CD28_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0033141 ! ITB3_HUMAN relationship: location_of CCO:B0034788 ! FCERB_HUMAN-Phosphotyrosine229 relationship: location_of CCO:B0035307 ! NRCAM_HUMAN-Phosphoserine427 relationship: location_of CCO:B0039914 ! TR13B_HUMAN relationship: location_of CCO:B0042813 ! IL2RB_HUMAN relationship: location_of CCO:B0042830 ! FCERA_HUMAN relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0050196 ! ITA2_HUMAN relationship: location_of CCO:B0051232 ! CLPT1_HUMAN relationship: location_of CCO:B0054667 ! RENR_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054916 ! CD3E_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055047 ! LEUK_HUMAN relationship: location_of CCO:B0055103 ! LAG3_HUMAN relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0055177 ! CD24_HUMAN relationship: location_of CCO:B0055192 ! NKG2D_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0055474 ! CCR5_HUMAN relationship: location_of CCO:B0055541 ! ITA1_HUMAN relationship: location_of CCO:B0055975 ! EMR1_HUMAN relationship: location_of CCO:B0056127 ! ENOX2_HUMAN relationship: location_of CCO:B0056401 ! Q59GA0_HUMAN relationship: location_of CCO:B0056685 ! CD276_HUMAN relationship: location_of CCO:B0058975 ! T2R16_HUMAN relationship: location_of CCO:B0059011 ! PD1L1_HUMAN relationship: location_of CCO:B0064171 ! CD5_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0065403 ! ADA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0066149 ! FCERG_HUMAN-Phosphotyrosine76 relationship: location_of CCO:B0067075 ! IL2RG_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 relationship: location_of CCO:B0067366 ! KIT_HUMAN-Phosphotyrosine703 relationship: part_of CCO:C0000709 ! cell surface [Term] id: CCO:C0000703 name: internal side of plasma membrane namespace: cellular_component def: "The side of the plasma membrane that faces the cytoplasm." [GOC:tb] subset: gosubset_prok synonym: "juxtamembrane" BROAD [] xref: GO:0009898 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0010887 ! CACB4_HUMAN-Phosphoserine508 relationship: location_of CCO:B0058574 ! GNB1L_HUMAN relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 [Term] id: CCO:C0000704 name: auxin efflux carrier complex namespace: cellular_component def: "The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell." [PMID:9843496] xref: GO:0009921 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0000705 name: fatty acid elongase complex namespace: cellular_component def: "A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids." [GOC:tb] xref: GO:0009923 is_a: CCO:C0001221 ! cytosolic fatty acid synthase complex [Term] id: CCO:C0000706 name: basal plasma membrane namespace: cellular_component def: "Part of the plasma membrane at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis." [GOC:go_curators] xref: GO:0009925 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0002059 ! LAP2_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0012916 ! MET_HUMAN-Phosphotyrosine1356 relationship: location_of CCO:B0034592 ! BPA1_HUMAN-Phosphothreonine224 relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0056547 ! ARH_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0062844 ! AQP5_HUMAN relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: part_of CCO:C0000780 ! basolateral plasma membrane relationship: part_of CCO:C0001897 ! basal part of cell [Term] id: CCO:C0000707 name: longitudinal side of cell surface namespace: cellular_component def: "The side of the cell parallel to the zygotic axis." [GOC:mtg_sensu, GOC:sm] synonym: "longitudinal side of cell surface (sensu Magnoliophyta)" RELATED [] xref: GO:0009930 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0000709 ! cell surface [Term] id: CCO:C0000708 name: chloroplast envelope namespace: cellular_component def: "The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:tb] xref: GO:0009941 is_a: CCO:C0000654 ! plastid envelope is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000709 name: cell surface namespace: cellular_component def: "The external part of the cell wall and/or plasma membrane." [GOC:jl, GOC:mtg_sensu, GOC:sm] comment: Note that this term is intended to annotate gene products that are attached to the plasma membrane or cell wall. subset: goslim_goa subset: goslim_pir subset: gosubset_prok synonym: "cell associated" EXACT [] synonym: "cell bound" EXACT [] synonym: "cell surface (sensu Magnoliophyta)" EXACT [] xref: GO:0009928 xref: GO:0009929 xref: GO:0009986 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0001379 ! FGF10_HUMAN relationship: location_of CCO:B0001469 ! PDGFB_HUMAN relationship: location_of CCO:B0001480 ! PDGFA_HUMAN relationship: location_of CCO:B0001563 ! CALR_HUMAN relationship: location_of CCO:B0001719 ! NOTC2_HUMAN relationship: location_of CCO:B0001767 ! BMPR2_HUMAN relationship: location_of CCO:B0005602 ! LIPA2_HUMAN relationship: location_of CCO:B0005828 ! GRP75_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0006207 ! MPP3_HUMAN relationship: location_of CCO:B0006244 ! TDGF1_HUMAN relationship: location_of CCO:B0006334 ! AMRP_HUMAN relationship: location_of CCO:B0010381 ! 4F2_HUMAN-Phosphothreonine5 relationship: location_of CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: location_of CCO:B0010450 ! ACV1B_HUMAN-Phosphotyrosine380 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0011734 ! EPHB4_HUMAN-Phosphotyrosine590 relationship: location_of CCO:B0011798 ! EWS_HUMAN-Asymmetric dimethylarginine589 relationship: location_of CCO:B0011879 ! FGFR2_HUMAN-Phosphotyrosine657 relationship: location_of CCO:B0012280 ! HSPB1_HUMAN-Phosphoserine26 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014612 ! VEGFA_HUMAN-N6-acetyllysine152 relationship: location_of CCO:B0015164 ! HHIP_HUMAN relationship: location_of CCO:B0020366 ! ACVL1_HUMAN relationship: location_of CCO:B0021671 ! HBEGF_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0030171 ! TLR2_HUMAN relationship: location_of CCO:B0031334 ! HSP7C_HUMAN-Phosphotyrosine41 relationship: location_of CCO:B0034557 ! ANXA9_HUMAN-Phosphoserine2 relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0038734 ! DPP4_HUMAN relationship: location_of CCO:B0042127 ! BMP10_HUMAN relationship: location_of CCO:B0043817 ! NGX6_HUMAN relationship: location_of CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0054457 ! IRAK2_HUMAN relationship: location_of CCO:B0054526 ! NRDC_HUMAN relationship: location_of CCO:B0054871 ! APOH_HUMAN relationship: location_of CCO:B0054926 ! ELNE_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055046 ! TIMP2_HUMAN relationship: location_of CCO:B0055053 ! PRLR_HUMAN relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0055145 ! ENPP1_HUMAN relationship: location_of CCO:B0055456 ! LU_HUMAN relationship: location_of CCO:B0055645 ! X3CL1_HUMAN relationship: location_of CCO:B0055723 ! UPAR_HUMAN relationship: location_of CCO:B0055940 ! AVR2B_HUMAN relationship: location_of CCO:B0056066 ! SHH_HUMAN relationship: location_of CCO:B0057108 ! ATS13_HUMAN relationship: location_of CCO:B0058018 ! GPR98_HUMAN relationship: location_of CCO:B0058105 ! GHSR_HUMAN relationship: location_of CCO:B0058129 ! KISSR_HUMAN relationship: location_of CCO:B0058328 ! DCBD2_HUMAN relationship: location_of CCO:B0058414 ! NOTC4_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058578 ! ACE2_HUMAN relationship: location_of CCO:B0058795 ! NOD2_HUMAN relationship: location_of CCO:B0058810 ! ROBO2_HUMAN relationship: location_of CCO:B0058838 ! TNR12_HUMAN relationship: location_of CCO:B0059282 ! TENN_HUMAN relationship: location_of CCO:B0062993 ! MDR1_HUMAN relationship: location_of CCO:B0063708 ! BAI3_HUMAN-Phosphoserine1220 relationship: location_of CCO:B0064565 ! CSPG4_HUMAN-Phosphothreonine21 relationship: location_of CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0065403 ! ADA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0066437 ! GDIB_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066887 ! HNRPU_HUMAN-Omega-N-methylated arginine732 relationship: location_of CCO:B0066926 ! HSP72_HUMAN-Phosphotyrosine108 relationship: location_of CCO:B0067159 ! ITA4_HUMAN-Phosphoserine1021 relationship: location_of CCO:B0068260 ! MPP2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0070125 ! ROBO1_HUMAN-Phosphotyrosine1038 relationship: location_of CCO:B0070575 ! SLAF1_HUMAN-Phosphotyrosine281 [Term] id: CCO:C0000710 name: cortical microtubule, transverse to long axis namespace: cellular_component def: "Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition." [ISBN:0943088399] synonym: "cortical microtubule (sensu Viridiplantae)" EXACT [] xref: GO:0010005 is_a: CCO:C0002014 ! cortical microtubule [Term] id: CCO:C0000711 name: Toc complex namespace: cellular_component def: "Protein translocon complex at the chloroplast outer membrane." [PMID:10646606] xref: GO:0010006 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000695 ! chloroplast outer membrane [Term] id: CCO:C0000712 name: magnesium chelatase complex namespace: cellular_component def: "A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner." [PMID:11842180] xref: GO:0010007 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000713 name: endosome membrane namespace: cellular_component def: "The lipid bilayer surrounding an endosome." [GOC:mah] xref: GO:0010008 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001859 ! endosomal part relationship: location_of CCO:B0001692 ! RHOB_HUMAN relationship: location_of CCO:B0001903 ! STEA3_HUMAN relationship: location_of CCO:B0001980 ! DP13B_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005237 ! RB22A_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0006299 ! VPS29_HUMAN relationship: location_of CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: location_of CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: location_of CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0022559 ! SLAP2_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0058264 ! RHOV_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058891 ! TLR9_HUMAN relationship: location_of CCO:B0058892 ! TLR8_HUMAN relationship: location_of CCO:B0058930 ! NFIP2_HUMAN relationship: location_of CCO:B0058995 ! SPG21_HUMAN relationship: location_of CCO:B0063303 ! VPP2_HUMAN relationship: location_of CCO:B0063516 ! M6PBP_HUMAN relationship: location_of CCO:B0066332 ! FYV1_HUMAN-Phosphotyrosine1772 relationship: location_of CCO:B0066584 ! GRB14_HUMAN-Phosphoserine372 relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071420 ! TLR7_HUMAN-Phosphoserine1010 [Term] id: CCO:C0000714 name: external side of endosome membrane namespace: cellular_component def: "The external (cytoplasmic face) of an endosome membrane." [GOC:lr] xref: GO:0010009 is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001859 ! endosomal part relationship: part_of CCO:C0000713 ! endosome membrane [Term] id: CCO:C0000715 name: ER body namespace: cellular_component def: "A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species." [PMID:11577182] synonym: "endoplasmic reticulum body" EXACT [] xref: GO:0010168 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000716 name: myrosinase complex namespace: cellular_component def: "A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds." [PMID:10682349] synonym: "thioglucosidase complex" EXACT [] xref: GO:0010169 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000717 name: glucose-1-phosphate adenylyltransferase complex namespace: cellular_component def: "Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits." [GOC:tb, PMID:12748181] subset: gosubset_prok xref: GO:0010170 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000718 name: plastid pyruvate dehydrogenase complex namespace: cellular_component def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria." [GOC:mtg_sensu, PMID:9393637] synonym: "dehydrogenase complex (sensu Viridiplantae)" EXACT [] xref: GO:0010240 is_a: CCO:C0001854 ! plastid part is_a: CCO:C0001917 ! pyruvate dehydrogenase complex [Term] id: CCO:C0000719 name: chloroplast outer membrane translocon namespace: cellular_component def: "The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner." [PMID:11299338] xref: GO:0010278 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000695 ! chloroplast outer membrane [Term] id: CCO:C0000720 name: senescence associated vacuole namespace: cellular_component def: "Vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast." [PMID:15743448] xref: GO:0010282 is_a: CCO:C0000061 ! lytic vacuole [Term] id: CCO:C0000721 name: plastoglobule namespace: cellular_component def: "Plastoglobules (PG) are lipoprotein particles present in chloroplasts. They are rich in non-polar lipids (triacylglycerols, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids." [GOC:TAIR_curator, PMID:16461379] xref: GO:0010287 is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000722 name: pyrophosphate-dependent phosphofructokinase complex namespace: cellular_component def: "Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate." [PMID:2170409] subset: goslim_pir synonym: "PFK complex" RELATED [] xref: GO:0010316 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000723 name: pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex namespace: cellular_component def: "Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity." [PMID:2170409] synonym: "PFK complex, alpha-subunit" RELATED [] xref: GO:0010317 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000722 ! pyrophosphate-dependent phosphofructokinase complex [Term] id: CCO:C0000724 name: pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex namespace: cellular_component def: "Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity." [PMID:2170409] synonym: "PFK complex, beta-subunit" RELATED [] xref: GO:0010318 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000722 ! pyrophosphate-dependent phosphofructokinase complex [Term] id: CCO:C0000725 name: stromule namespace: cellular_component def: "Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types." [PMID:15272881, PMID:15699062, PMID:16582010] synonym: "Stroma-filled tubule" RELATED [] xref: GO:0010319 is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000654 ! plastid envelope [Term] id: CCO:C0000726 name: cellulose synthase complex namespace: cellular_component def: "The multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall." [PMID:12514238] synonym: "cellulose synthase complex (sensu Viridiplantae)" EXACT [] xref: GO:0010330 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000727 name: external side of cell wall namespace: cellular_component def: "The side of the cell wall that is opposite to the side that faces the cell and its contents." [GOC:mtg_sensu, GOC:tb] xref: GO:0010339 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0000709 ! cell surface [Term] id: CCO:C0000728 name: extracellular isoamylase complex namespace: cellular_component def: "A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space." [GOC:tair_curators] subset: gosubset_prok xref: GO:0010367 is_a: CCO:C0001710 ! isoamylase complex is_a: CCO:C0001840 ! extracellular region part [Term] id: CCO:C0000729 name: chloroplast isoamylase complex namespace: cellular_component def: "A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localised." [GOC:tair_curators] subset: gosubset_prok xref: GO:0010368 is_a: CCO:C0001710 ! isoamylase complex is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0000730 name: chromocenter namespace: cellular_component def: "A region in which centric, heterochromatic portions of one or more chromosomes form a compact structure." [PMID:12384572, PMID:15053486, PMID:16831888] xref: GO:0010369 is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0063028 ! OIP5_HUMAN [Term] id: CCO:C0000731 name: perinucleolar chromocenter namespace: cellular_component def: "A chromocenter adjacent to the nucleolus." [PMID:15805479] xref: GO:0010370 is_a: CCO:C0000730 ! chromocenter [Term] id: CCO:C0000732 name: nuclear dicing body namespace: cellular_component def: "A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes." [PMID:17442570] synonym: "D body" EXACT [] xref: GO:0010445 is_a: CCO:C0000817 ! nuclear body [Term] id: CCO:C0000733 name: endomembrane system namespace: cellular_component def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] subset: goslim_candida subset: goslim_yeast xref: GO:0012505 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0002039 ! SIPA1_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0005183 ! PLDN_HUMAN relationship: location_of CCO:B0005421 ! BIK_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: location_of CCO:B0012433 ! JAK2_HUMAN-Phosphotyrosine1007 relationship: location_of CCO:B0012434 ! JAK3_HUMAN-Phosphothreonine8 relationship: location_of CCO:B0013388 ! PAR3L_HUMAN-Phosphoserine730 relationship: location_of CCO:B0013393 ! PARD3_HUMAN-Phosphoserine717 relationship: location_of CCO:B0015288 ! ARF1_HUMAN relationship: location_of CCO:B0019369 ! PIWL1_HUMAN relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0043552 ! PI51A_HUMAN relationship: location_of CCO:B0051370 ! FIBP_HUMAN relationship: location_of CCO:B0054320 ! DNM1L_HUMAN relationship: location_of CCO:B0054342 ! ACACB_HUMAN relationship: location_of CCO:B0054357 ! BORG1_HUMAN relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0054757 ! RPGF3_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055707 ! TNR17_HUMAN relationship: location_of CCO:B0056874 ! BORG3_HUMAN relationship: location_of CCO:B0057954 ! RN128_HUMAN relationship: location_of CCO:B0058222 ! MS4A3_HUMAN relationship: location_of CCO:B0058605 ! B2L14_HUMAN relationship: location_of CCO:B0059011 ! PD1L1_HUMAN relationship: location_of CCO:B0059029 ! VAPA_HUMAN relationship: location_of CCO:B0059110 ! VTI1B_HUMAN relationship: location_of CCO:B0063241 ! SNX18_HUMAN relationship: location_of CCO:B0063952 ! BORG2_HUMAN-Phosphoserine89 relationship: location_of CCO:B0063956 ! BORG4_HUMAN-Phosphoserine138 relationship: location_of CCO:B0063964 ! BORG5_HUMAN-Phosphoserine121 relationship: location_of CCO:B0065958 ! DOCK2_HUMAN-Phosphoserine1706 relationship: location_of CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 relationship: location_of CCO:B0068447 ! NBEA_HUMAN-Phosphoserine1529 relationship: location_of CCO:B0068709 ! NHERF_HUMAN-Phosphoserine288 relationship: location_of CCO:B0068715 ! NHRF2_HUMAN-Phosphoserine183 relationship: location_of CCO:B0068828 ! NRBP_HUMAN-Phosphothreonine441 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069705 ! RAC3_HUMAN-Cysteine methyl ester189 relationship: location_of CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 [Term] id: CCO:C0000734 name: vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." [GOC:mah] xref: GO:0012506 is_a: CCO:C0001127 ! organelle membrane relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0062975 ! WASP_HUMAN relationship: location_of CCO:B0068463 ! NCK1_HUMAN-Phosphoserine96 relationship: part_of CCO:C0000733 ! endomembrane system relationship: part_of CCO:C0002125 ! membrane-bounded vesicle [Term] id: CCO:C0000735 name: ER to Golgi transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi." [GOC:ai] synonym: "COPII coated vesicle membrane" EXACT [] synonym: "endoplasmic reticulum to Golgi transport vesicle membrane" EXACT [] synonym: "endoplasmic reticulum-Golgi transport vesicle membrane" EXACT [] synonym: "ER-Golgi transport vesicle membrane" EXACT [] xref: GO:0012507 xref: GO:0030664 is_a: CCO:C0001023 ! transport vesicle membrane is_a: CCO:C0001025 ! Golgi-associated vesicle membrane is_a: CCO:C0001027 ! coated vesicle membrane relationship: part_of CCO:C0000979 ! ER to Golgi transport vesicle [Term] id: CCO:C0000736 name: Golgi to ER transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER." [GOC:ai] synonym: "Golgi to endoplasmic reticulum transport vesicle membrane" EXACT [] synonym: "Golgi-endoplasmic reticulum transport vesicle membrane" EXACT [] synonym: "Golgi-ER transport vesicle membrane" EXACT [] xref: GO:0012508 is_a: CCO:C0001023 ! transport vesicle membrane is_a: CCO:C0001028 ! COPI coated vesicle membrane relationship: part_of CCO:C0000986 ! Golgi to ER transport vesicle [Term] id: CCO:C0000737 name: inter-Golgi transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle transporting substances within the Golgi." [GOC:ai] xref: GO:0012509 is_a: CCO:C0001023 ! transport vesicle membrane is_a: CCO:C0001028 ! COPI coated vesicle membrane relationship: part_of CCO:C0000987 ! inter-Golgi transport vesicle [Term] id: CCO:C0000738 name: trans-Golgi network transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell." [GOC:ai] synonym: "TGN transport vesicle membrane" EXACT [] xref: GO:0012510 is_a: CCO:C0001023 ! transport vesicle membrane is_a: CCO:C0001025 ! Golgi-associated vesicle membrane is_a: CCO:C0001029 ! clathrin coated vesicle membrane relationship: location_of CCO:B0054676 ! RASF9_HUMAN relationship: part_of CCO:C0000984 ! trans-Golgi network transport vesicle [Term] id: CCO:C0000739 name: monolayer-surrounded lipid storage body namespace: cellular_component def: "A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. A droplet of triacylglycerol surrounded by a monolayer of phospholipids, interacting with the triacylglycerols and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins." [GOC:mtg_sensu, ISBN:0943088372] synonym: "lipid storage body (sensu Viridiplantae)" EXACT [] synonym: "oil body" EXACT [] synonym: "oleosome" EXACT [] synonym: "spherosome" EXACT [] xref: GO:0009520 xref: GO:0012511 is_a: CCO:C0000382 ! lipid particle is_a: CCO:C0001745 ! intracellular organelle [Term] id: CCO:C0000740 name: postsynaptic density namespace: cellular_component def: "The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases." [GOC:ef, GOC:jic, http://molneuro.kaist.ac.kr/psd, http://wikipedia.org, PMID:14532281] xref: GO:0014069 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001875 ! synapse part relationship: location_of CCO:B0005692 ! CAC1C_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 [Term] id: CCO:C0000741 name: junctional sarcoplasmic reticulum membrane namespace: cellular_component def: "The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane." [GOC:mtg_muscle] xref: GO:0014701 is_a: CCO:C0001507 ! sarcoplasmic reticulum membrane [Term] id: CCO:C0000742 name: free sarcoplasmic reticulum membrane namespace: cellular_component def: "The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane." [GOC:mtg_muscle] xref: GO:0014702 is_a: CCO:C0001507 ! sarcoplasmic reticulum membrane [Term] id: CCO:C0000743 name: intercalated disc namespace: cellular_component def: "Specialised type of cell-cell junction in cardiac muscle, which mediates mechanical and electrochemical integration between the individual cardiomyocytes. Consist of three different kinds of substructures: adherens junctions, desmosomes and gap junctions." [GOC:mtg_muscle] xref: GO:0014704 is_a: CCO:C0000936 ! cell junction [Term] id: CCO:C0000744 name: C zone namespace: cellular_component def: "A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin." [GOC:mtg_muscle] xref: GO:0014705 is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0056023 ! MYPC3_HUMAN relationship: part_of CCO:C0001326 ! A band [Term] id: CCO:C0000745 name: spectrin-associated cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane." [GOC:mtg_muscle, PMID:15970557] xref: GO:0014731 is_a: CCO:C0000421 ! cytoskeleton [Term] id: CCO:C0000746 name: longitudinal sarcoplasmic reticulum namespace: cellular_component def: "The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae." [GOC:mtg_muscle] xref: GO:0014801 is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000802 ! sarcoplasmic reticulum [Term] id: CCO:C0000747 name: terminal cisterna namespace: cellular_component def: "The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release." [GOC:mtg_muscle] xref: GO:0014802 is_a: CCO:C0001376 ! organelle subcompartment is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000802 ! sarcoplasmic reticulum [Term] id: CCO:C0000748 name: longitudinal sarcoplasmic reticulum lumen namespace: cellular_component def: "The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lume contained within the terminal cisternae." [GOC:mtg_muscle] xref: GO:0014803 is_a: CCO:C0001508 ! sarcoplasmic reticulum lumen relationship: part_of CCO:C0000746 ! longitudinal sarcoplasmic reticulum [Term] id: CCO:C0000749 name: terminal cisterna lumen namespace: cellular_component def: "The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin." [GOC:mtg_muscle] xref: GO:0014804 is_a: CCO:C0001508 ! sarcoplasmic reticulum lumen relationship: part_of CCO:C0000747 ! terminal cisterna [Term] id: CCO:C0000750 name: Cajal body namespace: cellular_component def: "A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA." [http://genetics.cwru.edu/matera3.html, PMID:10944589, PMID:11031238, PMID:7559785] synonym: "coiled body" EXACT [] synonym: "Gems" EXACT [] xref: GO:0015030 is_a: CCO:C0000817 ! nuclear body relationship: location_of CCO:B0005621 ! P80C_HUMAN relationship: location_of CCO:B0063028 ! OIP5_HUMAN relationship: location_of CCO:B0070647 ! SMN_HUMAN-Phosphothreonine25 relationship: location_of CCO:B0071647 ! U2AF1_HUMAN-N-acetylalanine2 [Term] id: CCO:C0000751 name: methane monooxygenase complex namespace: cellular_component def: "A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized." [BRENDA:1.14.13.25, GOC:mah] subset: gosubset_prok xref: GO:0015050 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000752 name: type II protein secretion system complex namespace: cellular_component def: "A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane." [PMID:16448494] subset: gosubset_prok synonym: "general secretion pathway-associated complex" RELATED [] synonym: "main terminal branch" EXACT [] synonym: "MTB" EXACT [] synonym: "Sec-dependent secretion system-associated complex" RELATED [] synonym: "T2SS-associated complexes" EXACT [] synonym: "type II protein (Sec) secretion system complex" EXACT [] xref: GO:0015627 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000753 name: actin cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, http://cancerweb.ncl.ac.uk/, ISBN:0395825172] xref: GO:0015629 is_a: CCO:C0000421 ! cytoskeleton relationship: location_of CCO:B0002155 ! ANLN_HUMAN relationship: location_of CCO:B0005250 ! MYOZ2_HUMAN relationship: location_of CCO:B0005306 ! MYOZ1_HUMAN relationship: location_of CCO:B0005942 ! WASL_HUMAN relationship: location_of CCO:B0006125 ! CAPZB_HUMAN relationship: location_of CCO:B0006153 ! HAP1_HUMAN relationship: location_of CCO:B0006155 ! PROF2_HUMAN relationship: location_of CCO:B0006172 ! ARPC3_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0010794 ! BIN1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0013468 ! PDLI5_HUMAN-Phosphoserine136 relationship: location_of CCO:B0013541 ! PKD2_HUMAN-Phosphoserine254 relationship: location_of CCO:B0013613 ! PROF1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0018391 ! IQGA2_HUMAN relationship: location_of CCO:B0024099 ! ARPC2_HUMAN relationship: location_of CCO:B0028186 ! ARP2_HUMAN relationship: location_of CCO:B0031341 ! MTSS1_HUMAN-Phosphotyrosine526 relationship: location_of CCO:B0031598 ! ARC1A_HUMAN relationship: location_of CCO:B0033316 ! DEST_HUMAN relationship: location_of CCO:B0034567 ! ARP3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0035696 ! ST38L_HUMAN-Phosphoserine282 relationship: location_of CCO:B0036523 ! ST17B_HUMAN relationship: location_of CCO:B0039321 ! ARC1B_HUMAN-Phosphoserine310 relationship: location_of CCO:B0039340 ! CAZA1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0041285 ! CAZA2_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0043273 ! FLNA_HUMAN-Phosphoserine2284 relationship: location_of CCO:B0043276 ! FLNB_HUMAN-Phosphoserine983 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0048271 ! GRLF1_HUMAN-Phosphoserine970 relationship: location_of CCO:B0051606 ! VILL_HUMAN relationship: location_of CCO:B0052303 ! AVIL_HUMAN-Phosphotyrosine758 relationship: location_of CCO:B0052404 ! GELS_HUMAN-Phosphotyrosine603 relationship: location_of CCO:B0054441 ! ARPC5_HUMAN relationship: location_of CCO:B0054586 ! OPHN1_HUMAN relationship: location_of CCO:B0054982 ! MLRV_HUMAN relationship: location_of CCO:B0055127 ! NEBU_HUMAN relationship: location_of CCO:B0055265 ! LSP1_HUMAN relationship: location_of CCO:B0057419 ! ABRA_HUMAN relationship: location_of CCO:B0058261 ! PKNX2_HUMAN relationship: location_of CCO:B0058684 ! TARA_HUMAN relationship: location_of CCO:B0062975 ! WASP_HUMAN relationship: location_of CCO:B0063008 ! WIPF1_HUMAN relationship: location_of CCO:B0063156 ! SRBS2_HUMAN relationship: location_of CCO:B0063280 ! MYOTI_HUMAN relationship: location_of CCO:B0063952 ! BORG2_HUMAN-Phosphoserine89 relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064587 ! CTNL1_HUMAN-Phosphoserine538 relationship: location_of CCO:B0064733 ! DEMA_HUMAN-Phosphoserine156 relationship: location_of CCO:B0064879 ! DREB_HUMAN-Phosphothreonine331 relationship: location_of CCO:B0065282 ! ABLM1_HUMAN-Phosphoserine216 relationship: location_of CCO:B0066287 ! FSCN1_HUMAN-Phosphoserine39 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0067251 ! KALRN_HUMAN-Phosphoserine1750 relationship: location_of CCO:B0067657 ! LIMA1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0068709 ! NHERF_HUMAN-Phosphoserine288 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: location_of CCO:B0071778 ! VASP_HUMAN-Phosphotyrosine39 relationship: location_of CCO:B0071823 ! WASF2_HUMAN-Phosphoserine482 [Term] id: CCO:C0000754 name: microtubule cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172] xref: GO:0015630 is_a: CCO:C0000421 ! cytoskeleton relationship: location_of CCO:B0001446 ! CCNB2_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0001701 ! CCNA1_HUMAN relationship: location_of CCO:B0002162 ! RASF1_HUMAN relationship: location_of CCO:B0005281 ! M1IP1_HUMAN relationship: location_of CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011243 ! CKAP5_HUMAN-Phosphoserine816 relationship: location_of CCO:B0012776 ! MARK4_HUMAN-Phosphoserine26 relationship: location_of CCO:B0014528 ! TPX2_HUMAN-Phosphoserine654 relationship: location_of CCO:B0039483 ! KI18A_HUMAN-Phosphoserine357 relationship: location_of CCO:B0039502 ! MARK1_HUMAN-Phosphoserine394 relationship: location_of CCO:B0048362 ! PSRC1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0058261 ! PKNX2_HUMAN relationship: location_of CCO:B0062810 ! CP048_HUMAN relationship: location_of CCO:B0064387 ! CLIP1_HUMAN-Phosphoserine147 relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: location_of CCO:B0067803 ! LYST_HUMAN-Phosphoserine2213 relationship: location_of CCO:B0067988 ! MARE2_HUMAN-Phosphoserine208 [Term] id: CCO:C0000755 name: large ribosomal subunit namespace: cellular_component def: "The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site)." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "ribosomal large subunit" EXACT [] xref: GO:0015934 is_a: CCO:C0001567 ! ribosomal subunit relationship: location_of CCO:B0005746 ! RL7_HUMAN relationship: location_of CCO:B0070079 ! RL26_HUMAN-Phosphothreonine139 [Term] id: CCO:C0000756 name: small ribosomal subunit namespace: cellular_component def: "The smaller of the two subunits of a ribosome." [GOC:mah] subset: goslim_pir subset: gosubset_prok synonym: "ribosomal small subunit" EXACT [] xref: GO:0015935 is_a: CCO:C0001567 ! ribosomal subunit relationship: location_of CCO:B0005750 ! RS9_HUMAN relationship: location_of CCO:B0005776 ! RSSA_HUMAN relationship: location_of CCO:B0006095 ! RT12_HUMAN relationship: location_of CCO:B0006208 ! RT06_HUMAN relationship: location_of CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013939 ! RS20_HUMAN-Phosphothreonine9 relationship: location_of CCO:B0013940 ! RS24_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0030465 ! RS23_HUMAN relationship: location_of CCO:B0034271 ! RS25_HUMAN relationship: location_of CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: location_of CCO:B0055464 ! RT29_HUMAN relationship: location_of CCO:B0063061 ! RS5_HUMAN relationship: location_of CCO:B0063078 ! RS16_HUMAN relationship: location_of CCO:B0063353 ! RS26_HUMAN relationship: location_of CCO:B0063368 ! RS28_HUMAN relationship: location_of CCO:B0063474 ! RS2_HUMAN relationship: location_of CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 [Term] id: CCO:C0000757 name: Nebenkern namespace: cellular_component def: "A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme." [GOC:ma] xref: GO:0016006 is_a: CCO:C0000325 ! mitochondrion [Term] id: CCO:C0000758 name: mitochondrial derivative namespace: cellular_component def: "The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation." [GOC:ma] xref: GO:0016007 is_a: CCO:C0000325 ! mitochondrion [Term] id: CCO:C0000759 name: major mitochondrial derivative namespace: cellular_component def: "The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative." [GOC:mah, PMID:17123504] xref: GO:0016008 is_a: CCO:C0000758 ! mitochondrial derivative [Term] id: CCO:C0000760 name: minor mitochondrial derivative namespace: cellular_component def: "The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation." [GOC:mah, PMID:17123504] xref: GO:0016009 is_a: CCO:C0000758 ! mitochondrial derivative [Term] id: CCO:C0000761 name: dystrophin-associated glycoprotein complex namespace: cellular_component def: "A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase." [PMID:15117830, PMID:16710609] subset: goslim_pir synonym: "DGC" EXACT [] synonym: "dystrophin glycoprotein complex" EXACT [] xref: GO:0016010 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0070704 ! SNTB1_HUMAN-Phosphoserine389 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 [Term] id: CCO:C0000762 name: dystroglycan complex namespace: cellular_component def: "A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin." [PMID:15117830, PMID:16710609] xref: GO:0016011 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000761 ! dystrophin-associated glycoprotein complex [Term] id: CCO:C0000763 name: sarcoglycan complex namespace: cellular_component def: "A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex." [PMID:15117830, PMID:16710609] synonym: "sarcoglycan-sarcospan complex" EXACT [] xref: GO:0016012 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000762 ! dystroglycan complex [Term] id: CCO:C0000764 name: syntrophin complex namespace: cellular_component def: "A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase." [http://www.dmd.nl/DGC.html] xref: GO:0016013 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000761 ! dystrophin-associated glycoprotein complex [Term] id: CCO:C0000765 name: dystrobrevin complex namespace: cellular_component def: "A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex." [PMID:15117830, PMID:16710609] xref: GO:0016014 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000761 ! dystrophin-associated glycoprotein complex [Term] id: CCO:C0000766 name: membrane namespace: cellular_component def: "Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0016020 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0001362 ! EREG_HUMAN relationship: location_of CCO:B0001401 ! GAS2_HUMAN relationship: location_of CCO:B0001402 ! VEGFD_HUMAN relationship: location_of CCO:B0001406 ! ADCY3_HUMAN relationship: location_of CCO:B0001428 ! ERN1_HUMAN relationship: location_of CCO:B0001448 ! TNF15_HUMAN relationship: location_of CCO:B0001453 ! DIRA3_HUMAN relationship: location_of CCO:B0001455 ! RECK_HUMAN relationship: location_of CCO:B0001466 ! RASN_HUMAN relationship: location_of CCO:B0001469 ! PDGFB_HUMAN relationship: location_of CCO:B0001470 ! EGF_HUMAN relationship: location_of CCO:B0001473 ! TNFB_HUMAN relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0001477 ! IL2RA_HUMAN relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0001480 ! PDGFA_HUMAN relationship: location_of CCO:B0001490 ! LCK_HUMAN relationship: location_of CCO:B0001517 ! IFM1_HUMAN relationship: location_of CCO:B0001557 ! PAR1_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0001590 ! BTC_HUMAN relationship: location_of CCO:B0001591 ! PHB_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0001600 ! VHL_HUMAN relationship: location_of CCO:B0001611 ! FRAP_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0001633 ! PLGF_HUMAN relationship: location_of CCO:B0001634 ! VEGFB_HUMAN relationship: location_of CCO:B0001635 ! VEGFC_HUMAN relationship: location_of CCO:B0001666 ! HRSL3_HUMAN relationship: location_of CCO:B0001672 ! GAS1_HUMAN relationship: location_of CCO:B0001692 ! RHOB_HUMAN relationship: location_of CCO:B0001697 ! PP2AA_HUMAN relationship: location_of CCO:B0001719 ! NOTC2_HUMAN relationship: location_of CCO:B0001723 ! BAX_HUMAN relationship: location_of CCO:B0001737 ! STRN3_HUMAN relationship: location_of CCO:B0001758 ! ULA1_HUMAN relationship: location_of CCO:B0001765 ! PTC1_HUMAN relationship: location_of CCO:B0001767 ! BMPR2_HUMAN relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0001805 ! Q15354_HUMAN relationship: location_of CCO:B0001806 ! DHC24_HUMAN relationship: location_of CCO:B0001818 ! EXT1_HUMAN relationship: location_of CCO:B0001830 ! Q32M96_HUMAN relationship: location_of CCO:B0001838 ! PKHO1_HUMAN relationship: location_of CCO:B0001844 ! Q59FH5_HUMAN relationship: location_of CCO:B0001899 ! DAB2P_HUMAN relationship: location_of CCO:B0001903 ! STEA3_HUMAN relationship: location_of CCO:B0001904 ! KCD11_HUMAN relationship: location_of CCO:B0001909 ! RINT1_HUMAN relationship: location_of CCO:B0001920 ! Q6WZM0_HUMAN relationship: location_of CCO:B0001922 ! TM11A_HUMAN relationship: location_of CCO:B0001927 ! Q70WG0_HUMAN relationship: location_of CCO:B0001928 ! ERN2_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0001940 ! CUZD1_HUMAN relationship: location_of CCO:B0001947 ! EGFL6_HUMAN relationship: location_of CCO:B0001978 ! PPC1B_HUMAN relationship: location_of CCO:B0001980 ! DP13B_HUMAN relationship: location_of CCO:B0001983 ! CADM4_HUMAN relationship: location_of CCO:B0002020 ! APBB2_HUMAN relationship: location_of CCO:B0002023 ! ARHG1_HUMAN relationship: location_of CCO:B0002028 ! EXT2_HUMAN relationship: location_of CCO:B0002029 ! TP4A1_HUMAN relationship: location_of CCO:B0002039 ! SIPA1_HUMAN relationship: location_of CCO:B0002047 ! LMLN_HUMAN relationship: location_of CCO:B0002064 ! GML_HUMAN relationship: location_of CCO:B0002078 ! PMYT1_HUMAN relationship: location_of CCO:B0002094 ! LZTS2_HUMAN relationship: location_of CCO:B0002110 ! CADM1_HUMAN relationship: location_of CCO:B0002112 ! PAR6G_HUMAN relationship: location_of CCO:B0002113 ! PAR6B_HUMAN relationship: location_of CCO:B0002120 ! PDGFD_HUMAN relationship: location_of CCO:B0002135 ! PIGU_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0002150 ! PAR6A_HUMAN relationship: location_of CCO:B0002157 ! CP26B_HUMAN relationship: location_of CCO:B0002158 ! PDGFC_HUMAN relationship: location_of CCO:B0002175 ! NSMA2_HUMAN relationship: location_of CCO:B0002197 ! DMBT1_HUMAN relationship: location_of CCO:B0002198 ! SEPT3_HUMAN relationship: location_of CCO:B0002236 ! GP132_HUMAN relationship: location_of CCO:B0002245 ! JAG2_HUMAN relationship: location_of CCO:B0002248 ! LZTS1_HUMAN relationship: location_of CCO:B0002249 ! RUVB1_HUMAN relationship: location_of CCO:B0002253 ! STA13_HUMAN relationship: location_of CCO:B0005175 ! BAD_HUMAN relationship: location_of CCO:B0005183 ! PLDN_HUMAN relationship: location_of CCO:B0005197 ! AP2B1_HUMAN relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005215 ! FBLN4_HUMAN relationship: location_of CCO:B0005217 ! KCNRG_HUMAN relationship: location_of CCO:B0005220 ! STX11_HUMAN relationship: location_of CCO:B0005237 ! RB22A_HUMAN relationship: location_of CCO:B0005247 ! CHST1_HUMAN relationship: location_of CCO:B0005282 ! NOC4L_HUMAN relationship: location_of CCO:B0005283 ! TS101_HUMAN relationship: location_of CCO:B0005312 ! PEX26_HUMAN relationship: location_of CCO:B0005325 ! IL1R1_HUMAN relationship: location_of CCO:B0005338 ! CDC42_HUMAN relationship: location_of CCO:B0005364 ! RUVB2_HUMAN relationship: location_of CCO:B0005374 ! APLP2_HUMAN relationship: location_of CCO:B0005393 ! FEZ1_HUMAN relationship: location_of CCO:B0005421 ! BIK_HUMAN relationship: location_of CCO:B0005422 ! BID_HUMAN relationship: location_of CCO:B0005445 ! SDC2_HUMAN relationship: location_of CCO:B0005447 ! NRP1_HUMAN relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0005450 ! ICAM1_HUMAN relationship: location_of CCO:B0005455 ! CD166_HUMAN relationship: location_of CCO:B0005468 ! MED28_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005479 ! TNR6_HUMAN relationship: location_of CCO:B0005498 ! CREB3_HUMAN relationship: location_of CCO:B0005506 ! FSHR_HUMAN relationship: location_of CCO:B0005512 ! AKT1_HUMAN relationship: location_of CCO:B0005534 ! TNR1A_HUMAN relationship: location_of CCO:B0005535 ! TNR1B_HUMAN relationship: location_of CCO:B0005543 ! AVR2A_HUMAN relationship: location_of CCO:B0005545 ! NRX1A_HUMAN relationship: location_of CCO:B0005546 ! CELR3_HUMAN relationship: location_of CCO:B0005547 ! PLXB3_HUMAN relationship: location_of CCO:B0005549 ! MEG10_HUMAN relationship: location_of CCO:B0005569 ! PKHB2_HUMAN relationship: location_of CCO:B0005571 ! BAT5_HUMAN relationship: location_of CCO:B0005572 ! GNPTG_HUMAN relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005618 ! TRBM_HUMAN relationship: location_of CCO:B0005624 ! SCAM1_HUMAN relationship: location_of CCO:B0005628 ! ALK_HUMAN relationship: location_of CCO:B0005646 ! FGFP1_HUMAN relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0005669 ! ELMO1_HUMAN relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0005692 ! CAC1C_HUMAN relationship: location_of CCO:B0005706 ! M4K2_HUMAN relationship: location_of CCO:B0005707 ! TNR14_HUMAN relationship: location_of CCO:B0005711 ! P3C2B_HUMAN relationship: location_of CCO:B0005723 ! MTR1A_HUMAN relationship: location_of CCO:B0005724 ! MTR1B_HUMAN relationship: location_of CCO:B0005740 ! CD4_HUMAN relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0005760 ! NEP_HUMAN relationship: location_of CCO:B0005779 ! ENOA_HUMAN relationship: location_of CCO:B0005802 ! DOCK1_HUMAN relationship: location_of CCO:B0005845 ! LRC59_HUMAN relationship: location_of CCO:B0005851 ! DIRA2_HUMAN relationship: location_of CCO:B0005868 ! FGFR1_HUMAN relationship: location_of CCO:B0005870 ! TGFA_HUMAN relationship: location_of CCO:B0005875 ! CD59_HUMAN relationship: location_of CCO:B0005889 ! TAP1_HUMAN relationship: location_of CCO:B0005901 ! BCLX_HUMAN relationship: location_of CCO:B0005906 ! ERBB4_HUMAN relationship: location_of CCO:B0005928 ! VRK2_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0005950 ! BECN1_HUMAN relationship: location_of CCO:B0005957 ! MEGF8_HUMAN relationship: location_of CCO:B0005960 ! GRIP2_HUMAN relationship: location_of CCO:B0005974 ! NOTC1_HUMAN relationship: location_of CCO:B0005979 ! RFIP4_HUMAN relationship: location_of CCO:B0005993 ! TXD11_HUMAN relationship: location_of CCO:B0006003 ! BIM_HUMAN relationship: location_of CCO:B0006004 ! CSMD1_HUMAN relationship: location_of CCO:B0006010 ! TNR8_HUMAN relationship: location_of CCO:B0006019 ! LPP3_HUMAN relationship: location_of CCO:B0006022 ! PCDH9_HUMAN relationship: location_of CCO:B0006023 ! T3JAM_HUMAN relationship: location_of CCO:B0006024 ! EPHB6_HUMAN relationship: location_of CCO:B0006029 ! PANX3_HUMAN relationship: location_of CCO:B0006039 ! SMO_HUMAN relationship: location_of CCO:B0006083 ! SBP1_HUMAN relationship: location_of CCO:B0006099 ! PCDA4_HUMAN relationship: location_of CCO:B0006104 ! PTPRS_HUMAN relationship: location_of CCO:B0006116 ! TOM20_HUMAN relationship: location_of CCO:B0006131 ! KCRS_HUMAN relationship: location_of CCO:B0006132 ! CREL1_HUMAN relationship: location_of CCO:B0006141 ! FXYD6_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0006164 ! STX5_HUMAN relationship: location_of CCO:B0006179 ! APLP1_HUMAN relationship: location_of CCO:B0006187 ! SH3G3_HUMAN relationship: location_of CCO:B0006196 ! GBRAP_HUMAN relationship: location_of CCO:B0006201 ! IMMT_HUMAN relationship: location_of CCO:B0006216 ! PKHA4_HUMAN relationship: location_of CCO:B0006229 ! RIT1_HUMAN relationship: location_of CCO:B0006244 ! TDGF1_HUMAN relationship: location_of CCO:B0006259 ! BOC_HUMAN relationship: location_of CCO:B0006262 ! CD81_HUMAN relationship: location_of CCO:B0006268 ! ABCD4_HUMAN relationship: location_of CCO:B0006269 ! EFNA1_HUMAN relationship: location_of CCO:B0006270 ! ENOG_HUMAN relationship: location_of CCO:B0006271 ! BTBDA_HUMAN relationship: location_of CCO:B0006273 ! GPAA1_HUMAN relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0006285 ! GRIK5_HUMAN relationship: location_of CCO:B0006287 ! ERG28_HUMAN relationship: location_of CCO:B0006289 ! NDUB8_HUMAN relationship: location_of CCO:B0006292 ! PLXB2_HUMAN relationship: location_of CCO:B0006294 ! PTOV1_HUMAN relationship: location_of CCO:B0006299 ! VPS29_HUMAN relationship: location_of CCO:B0006306 ! GP135_HUMAN relationship: location_of CCO:B0006310 ! SH3G1_HUMAN relationship: location_of CCO:B0006313 ! SRPRB_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0006318 ! ITAE_HUMAN relationship: location_of CCO:B0006320 ! CHSS2_HUMAN relationship: location_of CCO:B0006326 ! PEF1_HUMAN relationship: location_of CCO:B0006331 ! GOLM1_HUMAN relationship: location_of CCO:B0006337 ! MYP0_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: location_of CCO:B0006346 ! SCN5A_HUMAN relationship: location_of CCO:B0006349 ! SCFD1_HUMAN relationship: location_of CCO:B0006350 ! VAMP8_HUMAN relationship: location_of CCO:B0010377 ! 2AAA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0010381 ! 4F2_HUMAN-Phosphothreonine5 relationship: location_of CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: location_of CCO:B0010427 ! ACK1_HUMAN-Phosphoserine149 relationship: location_of CCO:B0010450 ! ACV1B_HUMAN-Phosphotyrosine380 relationship: location_of CCO:B0010451 ! ADA15_HUMAN-Phosphotyrosine715 relationship: location_of CCO:B0010454 ! ADA17_HUMAN-Phosphoserine382 relationship: location_of CCO:B0010459 ! ADAM9_HUMAN-Phosphothreonine761 relationship: location_of CCO:B0010462 ! ADT2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0010497 ! AKT3_HUMAN-Phosphothreonine305 relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010637 ! AT1A1_HUMAN-Phosphothreonine219 relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0010790 ! BEGIN_HUMAN-Phosphoserine502 relationship: location_of CCO:B0010814 ! BMR1A_HUMAN-Phosphoserine220 relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011011 ! CCPG1_HUMAN-Phosphothreonine99 relationship: location_of CCO:B0011014 ! CD28_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0011050 ! CD45_HUMAN-Phosphoserine1003 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0011260 ! CLH2_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0011337 ! COX6C_HUMAN-N6-acetyllysine60 relationship: location_of CCO:B0011338 ! CPNS1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0011355 ! CSK_HUMAN-Phosphotyrosine304 relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0011392 ! CTND1_HUMAN-Phosphoserine269 relationship: location_of CCO:B0011460 ! DDR1_HUMAN-Phosphotyrosine792 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0011527 ! DLG5_HUMAN-Phosphothreonine1011 relationship: location_of CCO:B0011549 ! DNJA1_HUMAN-Phosphotyrosine381 relationship: location_of CCO:B0011550 ! DNJA2_HUMAN-Phosphoserine78 relationship: location_of CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: location_of CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0011697 ! EP15_HUMAN-Phosphoserine324 relationship: location_of CCO:B0011722 ! EPHA2_HUMAN-Phosphotyrosine594 relationship: location_of CCO:B0011731 ! EPHB2_HUMAN-Phosphothreonine775 relationship: location_of CCO:B0011734 ! EPHB4_HUMAN-Phosphotyrosine590 relationship: location_of CCO:B0011824 ! FAK1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011839 ! FAK2_HUMAN-Phosphotyrosine881 relationship: location_of CCO:B0011879 ! FGFR2_HUMAN-Phosphotyrosine657 relationship: location_of CCO:B0011886 ! FNBP1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0011899 ! FRMD6_HUMAN-Phosphoserine525 relationship: location_of CCO:B0011913 ! G3P_HUMAN-Phosphotyrosine42 relationship: location_of CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0011948 ! GNA13_HUMAN-Phosphothreonine203 relationship: location_of CCO:B0011955 ! GOGA2_HUMAN-Phosphoserine25 relationship: location_of CCO:B0011961 ! GORS2_HUMAN-Phosphothreonine225 relationship: location_of CCO:B0012178 ! HECAM_HUMAN-Phosphoserine318 relationship: location_of CCO:B0012186 ! HGS_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0012337 ! IGF1R_HUMAN-Phosphotyrosine1161 relationship: location_of CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: location_of CCO:B0012433 ! JAK2_HUMAN-Phosphotyrosine1007 relationship: location_of CCO:B0012434 ! JAK3_HUMAN-Phosphothreonine8 relationship: location_of CCO:B0012475 ! K2C1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0012522 ! KHDR1_HUMAN-Omega-N-methylarginine315 relationship: location_of CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0012697 ! LEPR_HUMAN-Phosphotyrosine1141 relationship: location_of CCO:B0012714 ! M2OM_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012916 ! MET_HUMAN-Phosphotyrosine1356 relationship: location_of CCO:B0012980 ! MPCP_HUMAN-N6-acetyllysine99 relationship: location_of CCO:B0013046 ! MTUS1_HUMAN-Phosphoserine1264 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013157 ! NELF_HUMAN-Phosphoserine288 relationship: location_of CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013388 ! PAR3L_HUMAN-Phosphoserine730 relationship: location_of CCO:B0013393 ! PARD3_HUMAN-Phosphoserine717 relationship: location_of CCO:B0013478 ! PDPK1_HUMAN-Phosphoserine241 relationship: location_of CCO:B0013493 ! PEX19_HUMAN-Phosphoserine184 relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0013541 ! PKD2_HUMAN-Phosphoserine254 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0013659 ! RAC1_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0013709 ! RAP1A_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0013716 ! RASK_HUMAN-ester186 relationship: location_of CCO:B0013718 ! RB27A_HUMAN-Cysteine methyl ester221 relationship: location_of CCO:B0013859 ! RHOG_HUMAN-Cysteine methyl ester188 relationship: location_of CCO:B0013872 ! RIN1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0014015 ! SEPT9_HUMAN-Phosphoserine89 relationship: location_of CCO:B0014052 ! SH3B4_HUMAN-Phosphoserine637 relationship: location_of CCO:B0014054 ! SH3G2_HUMAN-Phosphoserine75 relationship: location_of CCO:B0014175 ! SPG7_HUMAN-Nitrated tyrosine505 relationship: location_of CCO:B0014198 ! SPTB2_HUMAN-Phosphothreonine2195 relationship: location_of CCO:B0014200 ! SPTC2_HUMAN-Phosphotyrosine387 relationship: location_of CCO:B0014218 ! SSRA_HUMAN-Phosphoserine268 relationship: location_of CCO:B0014272 ! SUMO1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0014349 ! TGFR2_HUMAN-Phosphoserine548 relationship: location_of CCO:B0014416 ! TM1L1_HUMAN-Phosphoserine323 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0014576 ! UFO_HUMAN-Phosphotyrosine696 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0014603 ! VDAC2_HUMAN-Phosphoserine115 relationship: location_of CCO:B0014607 ! VDAC3_HUMAN-N6-acetyllysine61 relationship: location_of CCO:B0014612 ! VEGFA_HUMAN-N6-acetyllysine152 relationship: location_of CCO:B0014615 ! VGFR1_HUMAN-Phosphotyrosine1213 relationship: location_of CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0014899 ! IPSP_HUMAN relationship: location_of CCO:B0014946 ! EPHAA_HUMAN relationship: location_of CCO:B0014947 ! Q6UWM0_HUMAN relationship: location_of CCO:B0014952 ! Q6P4R6_HUMAN relationship: location_of CCO:B0014956 ! Q96L35_HUMAN relationship: location_of CCO:B0014957 ! EPHA8_HUMAN relationship: location_of CCO:B0014960 ! Q8N3Z2_HUMAN relationship: location_of CCO:B0014962 ! A8CDT5_HUMAN relationship: location_of CCO:B0014963 ! Q8IUX6_HUMAN relationship: location_of CCO:B0015065 ! CRTAM_HUMAN relationship: location_of CCO:B0015122 ! GLR_HUMAN relationship: location_of CCO:B0015123 ! GLP1R_HUMAN relationship: location_of CCO:B0015124 ! GIPR_HUMAN relationship: location_of CCO:B0015126 ! Q8NHB4_HUMAN relationship: location_of CCO:B0015129 ! Q6ZN22_HUMAN relationship: location_of CCO:B0015134 ! GLP2R_HUMAN relationship: location_of CCO:B0015136 ! SCTR_HUMAN relationship: location_of CCO:B0015164 ! HHIP_HUMAN relationship: location_of CCO:B0015543 ! SMAP1_HUMAN relationship: location_of CCO:B0015673 ! CHL1_HUMAN relationship: location_of CCO:B0015778 ! PILRB_HUMAN relationship: location_of CCO:B0015779 ! PILRA_HUMAN relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0016682 ! GUC2D_HUMAN relationship: location_of CCO:B0016684 ! GUC2F_HUMAN relationship: location_of CCO:B0016685 ! GUC2C_HUMAN relationship: location_of CCO:B0016857 ! Q0MSE7_HUMAN relationship: location_of CCO:B0016858 ! Q6JTU6_HUMAN relationship: location_of CCO:B0016862 ! Q6V402_HUMAN relationship: location_of CCO:B0016863 ! Q8WYM0_HUMAN relationship: location_of CCO:B0016865 ! Q6TE14_HUMAN relationship: location_of CCO:B0016974 ! PK2L1_HUMAN relationship: location_of CCO:B0016983 ! Q8NH25_HUMAN relationship: location_of CCO:B0016986 ! P2RY8_HUMAN relationship: location_of CCO:B0017344 ! RET_HUMAN relationship: location_of CCO:B0017773 ! T2R40_HUMAN relationship: location_of CCO:B0017820 ! NOTC3_HUMAN relationship: location_of CCO:B0018438 ! CCRL1_HUMAN relationship: location_of CCO:B0018485 ! CLTR2_HUMAN relationship: location_of CCO:B0018486 ! CLTR1_HUMAN relationship: location_of CCO:B0018655 ! RYK_HUMAN relationship: location_of CCO:B0018695 ! EDNRA_HUMAN relationship: location_of CCO:B0018697 ! EDNRB_HUMAN relationship: location_of CCO:B0018701 ! Q9BUD7_HUMAN relationship: location_of CCO:B0018717 ! Q9UK79_HUMAN relationship: location_of CCO:B0018761 ! M3K13_HUMAN relationship: location_of CCO:B0018778 ! M3K12_HUMAN relationship: location_of CCO:B0018951 ! ATF6A_HUMAN relationship: location_of CCO:B0019132 ! RHG17_HUMAN relationship: location_of CCO:B0019141 ! ASGR1_HUMAN relationship: location_of CCO:B0019143 ! ASGR2_HUMAN relationship: location_of CCO:B0019369 ! PIWL1_HUMAN relationship: location_of CCO:B0019510 ! TAOK3_HUMAN relationship: location_of CCO:B0019513 ! TAOK2_HUMAN relationship: location_of CCO:B0019541 ! TMPS6_HUMAN relationship: location_of CCO:B0019877 ! Q7KZS6_HUMAN relationship: location_of CCO:B0019991 ! A2ABL4_HUMAN relationship: location_of CCO:B0020052 ! CHIC2_HUMAN relationship: location_of CCO:B0020113 ! FBCD1_HUMAN relationship: location_of CCO:B0020193 ! SL9A2_HUMAN relationship: location_of CCO:B0020207 ! KCIP1_HUMAN relationship: location_of CCO:B0020218 ! CSEN_HUMAN relationship: location_of CCO:B0020366 ! ACVL1_HUMAN relationship: location_of CCO:B0020367 ! Q6IR47_HUMAN relationship: location_of CCO:B0020368 ! ACV1C_HUMAN relationship: location_of CCO:B0020371 ! BMR1B_HUMAN relationship: location_of CCO:B0020481 ! RET1G_HUMAN relationship: location_of CCO:B0020491 ! N2DL3_HUMAN relationship: location_of CCO:B0020561 ! PLD2_HUMAN relationship: location_of CCO:B0020591 ! RHOA_HUMAN relationship: location_of CCO:B0020594 ! RHOC_HUMAN relationship: location_of CCO:B0020605 ! GRIK3_HUMAN relationship: location_of CCO:B0020611 ! GRIK2_HUMAN relationship: location_of CCO:B0020614 ! GRIK1_HUMAN relationship: location_of CCO:B0020617 ! GRIK4_HUMAN relationship: location_of CCO:B0020623 ! GRIA4_HUMAN relationship: location_of CCO:B0020764 ! RGS20_HUMAN relationship: location_of CCO:B0020771 ! RGS3_HUMAN relationship: location_of CCO:B0020874 ! ADCY2_HUMAN relationship: location_of CCO:B0020879 ! ADCY7_HUMAN relationship: location_of CCO:B0020880 ! ADCY4_HUMAN relationship: location_of CCO:B0021202 ! A2A3C6_HUMAN relationship: location_of CCO:B0021203 ! A2A3C1_HUMAN relationship: location_of CCO:B0021206 ! A2A3C4_HUMAN relationship: location_of CCO:B0021208 ! A2A3C2_HUMAN relationship: location_of CCO:B0021209 ! A2A3C3_HUMAN relationship: location_of CCO:B0021210 ! BAI2_HUMAN relationship: location_of CCO:B0021417 ! CALRL_HUMAN relationship: location_of CCO:B0021419 ! A4D1G6_HUMAN relationship: location_of CCO:B0021435 ! ATF4_HUMAN relationship: location_of CCO:B0021450 ! ADR2_HUMAN relationship: location_of CCO:B0021461 ! ADR1_HUMAN relationship: location_of CCO:B0021658 ! NDUS6_HUMAN relationship: location_of CCO:B0021671 ! HBEGF_HUMAN relationship: location_of CCO:B0021887 ! I17RB_HUMAN relationship: location_of CCO:B0022071 ! TLR4_HUMAN relationship: location_of CCO:B0022559 ! SLAP2_HUMAN relationship: location_of CCO:B0022719 ! Q6IF88_HUMAN relationship: location_of CCO:B0022721 ! OR5K3_HUMAN relationship: location_of CCO:B0022723 ! OR5K1_HUMAN relationship: location_of CCO:B0022725 ! Q8NHB6_HUMAN relationship: location_of CCO:B0022726 ! O5AC2_HUMAN relationship: location_of CCO:B0022728 ! OR5H1_HUMAN relationship: location_of CCO:B0022729 ! O5H15_HUMAN relationship: location_of CCO:B0022731 ! OR5K2_HUMAN relationship: location_of CCO:B0022762 ! CASS4_HUMAN relationship: location_of CCO:B0022781 ! PIM1_HUMAN relationship: location_of CCO:B0022838 ! Q8NEI9_HUMAN relationship: location_of CCO:B0022839 ! Q8NHC0_HUMAN relationship: location_of CCO:B0022840 ! Q8NH98_HUMAN relationship: location_of CCO:B0022842 ! Q8NH65_HUMAN relationship: location_of CCO:B0022843 ! Q9UPJ0_HUMAN relationship: location_of CCO:B0022845 ! Q8NHB5_HUMAN relationship: location_of CCO:B0022847 ! Q8NH99_HUMAN relationship: location_of CCO:B0022848 ! Q9P1R1_HUMAN relationship: location_of CCO:B0022849 ! Q8NH46_HUMAN relationship: location_of CCO:B0022852 ! Q8NGT4_HUMAN relationship: location_of CCO:B0022854 ! Q8NHC1_HUMAN relationship: location_of CCO:B0022857 ! Q8NHB9_HUMAN relationship: location_of CCO:B0022858 ! Q8NH45_HUMAN relationship: location_of CCO:B0022861 ! O7E24_HUMAN relationship: location_of CCO:B0022862 ! Q9UDD8_HUMAN relationship: location_of CCO:B0022865 ! Q8NHA1_HUMAN relationship: location_of CCO:B0022866 ! Q8NG89_HUMAN relationship: location_of CCO:B0022870 ! Q96N54_HUMAN relationship: location_of CCO:B0022873 ! Q8NGD7_HUMAN relationship: location_of CCO:B0022899 ! GBRR2_HUMAN relationship: location_of CCO:B0022900 ! GBRG3_HUMAN relationship: location_of CCO:B0022901 ! GBRE_HUMAN relationship: location_of CCO:B0022902 ! Q8IYR7_HUMAN relationship: location_of CCO:B0022903 ! GBRT_HUMAN relationship: location_of CCO:B0022906 ! GBRG1_HUMAN relationship: location_of CCO:B0022907 ! GBRA6_HUMAN relationship: location_of CCO:B0022909 ! GBRG2_HUMAN relationship: location_of CCO:B0022911 ! GLRB_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022914 ! GBRA1_HUMAN relationship: location_of CCO:B0022915 ! GBRA5_HUMAN relationship: location_of CCO:B0022917 ! GLRA2_HUMAN relationship: location_of CCO:B0022924 ! GBRA2_HUMAN relationship: location_of CCO:B0022926 ! GBRR1_HUMAN relationship: location_of CCO:B0022931 ! GBRD_HUMAN relationship: location_of CCO:B0022933 ! GBRA3_HUMAN relationship: location_of CCO:B0022935 ! Q6PCC3_HUMAN relationship: location_of CCO:B0022999 ! PTPRK_HUMAN relationship: location_of CCO:B0023006 ! PTPRT_HUMAN relationship: location_of CCO:B0023019 ! PTPRU_HUMAN relationship: location_of CCO:B0023169 ! A6NMR0_HUMAN relationship: location_of CCO:B0023179 ! NPTN_HUMAN relationship: location_of CCO:B0023320 ! DLG2_HUMAN relationship: location_of CCO:B0023521 ! CD2_HUMAN relationship: location_of CCO:B0023550 ! RAB5C_HUMAN relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0024306 ! PSYR_HUMAN relationship: location_of CCO:B0024308 ! GPR4_HUMAN relationship: location_of CCO:B0024312 ! DLL3_HUMAN relationship: location_of CCO:B0024407 ! RAP2C_HUMAN relationship: location_of CCO:B0024484 ! PLCB3_HUMAN relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0025070 ! PDZD3_HUMAN relationship: location_of CCO:B0025098 ! LETM1_HUMAN relationship: location_of CCO:B0025167 ! TRPC5_HUMAN relationship: location_of CCO:B0025169 ! TRPC1_HUMAN relationship: location_of CCO:B0025184 ! IL6RB_HUMAN relationship: location_of CCO:B0025350 ! DIRA1_HUMAN relationship: location_of CCO:B0025401 ! MS4A7_HUMAN relationship: location_of CCO:B0025531 ! A2A2V4_HUMAN relationship: location_of CCO:B0025847 ! PTPRN_HUMAN relationship: location_of CCO:B0025951 ! LRP5_HUMAN relationship: location_of CCO:B0025967 ! LRP6_HUMAN relationship: location_of CCO:B0026105 ! GRAN_HUMAN relationship: location_of CCO:B0026166 ! LANC1_HUMAN relationship: location_of CCO:B0026210 ! Q59FA8_HUMAN relationship: location_of CCO:B0026213 ! ITA8_HUMAN relationship: location_of CCO:B0026215 ! ITA2B_HUMAN relationship: location_of CCO:B0026216 ! Q17R67_HUMAN relationship: location_of CCO:B0026217 ! ITA5_HUMAN relationship: location_of CCO:B0026218 ! ITAV_HUMAN relationship: location_of CCO:B0026247 ! A2NWD3_HUMAN relationship: location_of CCO:B0026256 ! RPRM_HUMAN relationship: location_of CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: location_of CCO:B0026448 ! AT2C1_HUMAN relationship: location_of CCO:B0026622 ! A8MTK9_HUMAN relationship: location_of CCO:B0026726 ! MRGRF_HUMAN relationship: location_of CCO:B0026846 ! CNTFR_HUMAN relationship: location_of CCO:B0026851 ! HERP1_HUMAN relationship: location_of CCO:B0026865 ! SORC1_HUMAN relationship: location_of CCO:B0026866 ! SORC3_HUMAN relationship: location_of CCO:B0026867 ! SORC2_HUMAN relationship: location_of CCO:B0026912 ! PEX6_HUMAN relationship: location_of CCO:B0027056 ! A8MWU7_HUMAN relationship: location_of CCO:B0027058 ! A8MX51_HUMAN relationship: location_of CCO:B0027148 ! S61A2_HUMAN relationship: location_of CCO:B0027154 ! S61A1_HUMAN relationship: location_of CCO:B0027270 ! FDFT_HUMAN relationship: location_of CCO:B0027593 ! CDIPT_HUMAN relationship: location_of CCO:B0027730 ! SIN1_HUMAN relationship: location_of CCO:B0028140 ! VATL_HUMAN relationship: location_of CCO:B0028201 ! OR1D2_HUMAN relationship: location_of CCO:B0028205 ! Q6IFM2_HUMAN relationship: location_of CCO:B0028206 ! Q6IFL7_HUMAN relationship: location_of CCO:B0028290 ! JAG1_HUMAN relationship: location_of CCO:B0028291 ! DLL4_HUMAN relationship: location_of CCO:B0028292 ! DLL1_HUMAN relationship: location_of CCO:B0028582 ! Q5TE64_HUMAN relationship: location_of CCO:B0028758 ! SPTC1_HUMAN relationship: location_of CCO:B0028914 ! AB1IP_HUMAN relationship: location_of CCO:B0029013 ! OR9I1_HUMAN relationship: location_of CCO:B0029014 ! Q6IF62_HUMAN relationship: location_of CCO:B0029015 ! OR5W2_HUMAN relationship: location_of CCO:B0029017 ! OR5B3_HUMAN relationship: location_of CCO:B0029019 ! Q8NH91_HUMAN relationship: location_of CCO:B0029022 ! OR8K5_HUMAN relationship: location_of CCO:B0029023 ! OR5L1_HUMAN relationship: location_of CCO:B0029024 ! OR5B2_HUMAN relationship: location_of CCO:B0029025 ! OR8U1_HUMAN relationship: location_of CCO:B0029027 ! A8MUX1_HUMAN relationship: location_of CCO:B0029028 ! OR5BC_HUMAN relationship: location_of CCO:B0029029 ! OR5R1_HUMAN relationship: location_of CCO:B0029030 ! OR5C1_HUMAN relationship: location_of CCO:B0029031 ! OR8G5_HUMAN relationship: location_of CCO:B0029033 ! OR5J2_HUMAN relationship: location_of CCO:B0029034 ! OR8D4_HUMAN relationship: location_of CCO:B0029035 ! O5AR1_HUMAN relationship: location_of CCO:B0029036 ! Q6IFM9_HUMAN relationship: location_of CCO:B0029037 ! A8MXK6_HUMAN relationship: location_of CCO:B0029038 ! O5AS1_HUMAN relationship: location_of CCO:B0029039 ! OR5BH_HUMAN relationship: location_of CCO:B0029040 ! OR5L2_HUMAN relationship: location_of CCO:B0029064 ! Q17RW0_HUMAN relationship: location_of CCO:B0029727 ! CEAM1_HUMAN relationship: location_of CCO:B0030075 ! A8MTR7_HUMAN relationship: location_of CCO:B0030164 ! TLR1_HUMAN relationship: location_of CCO:B0030165 ! TLR10_HUMAN relationship: location_of CCO:B0030171 ! TLR2_HUMAN relationship: location_of CCO:B0030172 ! TLR6_HUMAN relationship: location_of CCO:B0030249 ! GNAZ_HUMAN relationship: location_of CCO:B0030278 ! RND1_HUMAN relationship: location_of CCO:B0030280 ! RND2_HUMAN relationship: location_of CCO:B0030552 ! MC3R_HUMAN relationship: location_of CCO:B0030561 ! MSHR_HUMAN relationship: location_of CCO:B0030569 ! MC5R_HUMAN relationship: location_of CCO:B0030574 ! MC4R_HUMAN relationship: location_of CCO:B0030577 ! ACTHR_HUMAN relationship: location_of CCO:B0030651 ! AMHR2_HUMAN relationship: location_of CCO:B0030652 ! Q13161_HUMAN relationship: location_of CCO:B0030754 ! VAMP3_HUMAN-Phosphoserine58 relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: location_of CCO:B0030995 ! IRK2_HUMAN relationship: location_of CCO:B0031198 ! MOBL3_HUMAN relationship: location_of CCO:B0031296 ! AT1B1_HUMAN-Phosphotyrosine101 relationship: location_of CCO:B0031317 ! FGFR3_HUMAN-Phosphotyrosine647 relationship: location_of CCO:B0031369 ! PTN6_HUMAN-Phosphotyrosine377 relationship: location_of CCO:B0031499 ! GBP2_HUMAN relationship: location_of CCO:B0031540 ! APC2_HUMAN relationship: location_of CCO:B0031607 ! TA2R5_HUMAN relationship: location_of CCO:B0031787 ! NOE2_HUMAN relationship: location_of CCO:B0032298 ! I17RA_HUMAN relationship: location_of CCO:B0032345 ! Q5Y190_HUMAN relationship: location_of CCO:B0032349 ! CELR2_HUMAN relationship: location_of CCO:B0032391 ! MTND_HUMAN relationship: location_of CCO:B0032548 ! RAB8A_HUMAN relationship: location_of CCO:B0032549 ! RAB10_HUMAN relationship: location_of CCO:B0032550 ! RAB8B_HUMAN relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0032799 ! ACHB3_HUMAN relationship: location_of CCO:B0032804 ! ACHA3_HUMAN relationship: location_of CCO:B0032806 ! ACHA5_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0032809 ! ACHA2_HUMAN relationship: location_of CCO:B0033120 ! ITB5_HUMAN relationship: location_of CCO:B0033125 ! ITB8_HUMAN relationship: location_of CCO:B0033128 ! Q59FN1_HUMAN relationship: location_of CCO:B0033132 ! Q59H50_HUMAN relationship: location_of CCO:B0033133 ! ITB6_HUMAN relationship: location_of CCO:B0033134 ! A8MYE6_HUMAN relationship: location_of CCO:B0033136 ! Q8WUM6_HUMAN relationship: location_of CCO:B0033137 ! ITB7_HUMAN relationship: location_of CCO:B0033141 ! ITB3_HUMAN relationship: location_of CCO:B0033173 ! Q59FU8_HUMAN relationship: location_of CCO:B0033174 ! Q5T9P3_HUMAN relationship: location_of CCO:B0033252 ! OPSX_HUMAN relationship: location_of CCO:B0033253 ! A6NEB4_HUMAN relationship: location_of CCO:B0033254 ! OPN4_HUMAN relationship: location_of CCO:B0033332 ! RGS14_HUMAN relationship: location_of CCO:B0033335 ! Q6IFC7_HUMAN relationship: location_of CCO:B0033337 ! A8MTX1_HUMAN relationship: location_of CCO:B0033338 ! OR5T1_HUMAN relationship: location_of CCO:B0033339 ! A8MW53_HUMAN relationship: location_of CCO:B0033340 ! O5AK3_HUMAN relationship: location_of CCO:B0033341 ! OR5K4_HUMAN relationship: location_of CCO:B0033342 ! A8MWJ9_HUMAN relationship: location_of CCO:B0033343 ! Q6IFC8_HUMAN relationship: location_of CCO:B0033344 ! OR9Q2_HUMAN relationship: location_of CCO:B0033345 ! A8MXY9_HUMAN relationship: location_of CCO:B0033346 ! OR5I1_HUMAN relationship: location_of CCO:B0033347 ! O5AC1_HUMAN relationship: location_of CCO:B0033348 ! A8MVK2_HUMAN relationship: location_of CCO:B0033349 ! O5H14_HUMAN relationship: location_of CCO:B0033351 ! Q8IXE7_HUMAN relationship: location_of CCO:B0033365 ! LASS4_HUMAN relationship: location_of CCO:B0033366 ! LASS3_HUMAN relationship: location_of CCO:B0033369 ! LASS6_HUMAN relationship: location_of CCO:B0033376 ! Q5SZE4_HUMAN relationship: location_of CCO:B0033382 ! Q32M63_HUMAN relationship: location_of CCO:B0033383 ! A8K4M4_HUMAN relationship: location_of CCO:B0033402 ! Q14CE0_HUMAN relationship: location_of CCO:B0033403 ! Q6F3F5_HUMAN relationship: location_of CCO:B0033404 ! Q6F3F6_HUMAN relationship: location_of CCO:B0033406 ! A2A2J1_HUMAN relationship: location_of CCO:B0033407 ! A2A2J2_HUMAN relationship: location_of CCO:B0033410 ! A9Z1X2_HUMAN relationship: location_of CCO:B0033411 ! Q6F3F8_HUMAN relationship: location_of CCO:B0033412 ! GP112_HUMAN relationship: location_of CCO:B0033414 ! Q499H0_HUMAN relationship: location_of CCO:B0033415 ! Q5EGP2_HUMAN relationship: location_of CCO:B0033418 ! GPR64_HUMAN relationship: location_of CCO:B0033419 ! Q6F3F7_HUMAN relationship: location_of CCO:B0033477 ! LRP8_HUMAN relationship: location_of CCO:B0034023 ! S26A5_HUMAN relationship: location_of CCO:B0034159 ! AQP1_HUMAN relationship: location_of CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0034526 ! AFG32_HUMAN-N6-acetyllysine308 relationship: location_of CCO:B0034532 ! AMD_HUMAN-Phosphoserine955 relationship: location_of CCO:B0034546 ! ANPRA_HUMAN-Phosphoserine534 relationship: location_of CCO:B0034552 ! ANPRB_HUMAN-Phosphoserine518 relationship: location_of CCO:B0034583 ! B2L13_HUMAN-Phosphoserine420 relationship: location_of CCO:B0034706 ! DLG4_HUMAN-Phosphotyrosine432 relationship: location_of CCO:B0034728 ! EPHA1_HUMAN-Phosphoserine34 relationship: location_of CCO:B0034734 ! EPHA3_HUMAN-Phosphotyrosine596 relationship: location_of CCO:B0034739 ! EPHA4_HUMAN-Phosphotyrosine602 relationship: location_of CCO:B0034742 ! EPHA5_HUMAN-Phosphotyrosine650 relationship: location_of CCO:B0034746 ! EPHA6_HUMAN-Phosphotyrosine605 relationship: location_of CCO:B0034753 ! EPHA7_HUMAN-Phosphotyrosine940 relationship: location_of CCO:B0034756 ! EPHB1_HUMAN-Phosphotyrosine594 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0034788 ! FCERB_HUMAN-Phosphotyrosine229 relationship: location_of CCO:B0034813 ! FPR1_HUMAN-Phosphothreonine339 relationship: location_of CCO:B0034822 ! G3BP1_HUMAN-Omega-N-methylated arginine460 relationship: location_of CCO:B0034864 ! I12R2_HUMAN-Phosphotyrosine800 relationship: location_of CCO:B0034872 ! IL3RB_HUMAN-Phosphotyrosine766 relationship: location_of CCO:B0034880 ! IQGA1_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0034889 ! ITB2_HUMAN-Phosphothreonine759 relationship: location_of CCO:B0034894 ! ITB4_HUMAN-Phosphoserine1084 relationship: location_of CCO:B0034992 ! KCC2A_HUMAN-Phosphothreonine286 relationship: location_of CCO:B0035046 ! KPCB_HUMAN-Phosphothreonine504 relationship: location_of CCO:B0035082 ! L1CAM_HUMAN-Phosphoserine1248 relationship: location_of CCO:B0035087 ! LANC2_HUMAN-Phosphotyrosine295 relationship: location_of CCO:B0035088 ! LASS2_HUMAN-Phosphoserine341 relationship: location_of CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: location_of CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: location_of CCO:B0035174 ! MBP_HUMAN-Phosphoserine205 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035292 ! NMDE4_HUMAN-Phosphoserine1326 relationship: location_of CCO:B0035307 ! NRCAM_HUMAN-Phosphoserine427 relationship: location_of CCO:B0035358 ! PECA1_HUMAN-Phosphotyrosine713 relationship: location_of CCO:B0035368 ! PGFRB_HUMAN-Phosphotyrosine857 relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0035507 ! RAP1B_HUMAN-ADP-ribosylserine39 relationship: location_of CCO:B0035510 ! RAP2A_HUMAN-Cysteine methyl ester180 relationship: location_of CCO:B0035511 ! RAP2B_HUMAN-Cysteine methyl ester180 relationship: location_of CCO:B0035556 ! RGS17_HUMAN-Phosphotyrosine137 relationship: location_of CCO:B0035557 ! RGS19_HUMAN-Phosphoserine24 relationship: location_of CCO:B0035594 ! RND3_HUMAN-Cysteine methyl ester241 relationship: location_of CCO:B0035599 ! RRAS2_HUMAN-Cysteine methyl ester201 relationship: location_of CCO:B0035600 ! RRAS_HUMAN-Cysteine methyl ester215 relationship: location_of CCO:B0035712 ! STMN2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0035817 ! TRPC4_HUMAN-Phosphoserine195 relationship: location_of CCO:B0035937 ! S26A8_HUMAN relationship: location_of CCO:B0035985 ! ACVR1_HUMAN-Phosphoserine501 relationship: location_of CCO:B0035998 ! DCC_HUMAN-Phosphothreonine1074 relationship: location_of CCO:B0036139 ! SENP2_HUMAN relationship: location_of CCO:B0036594 ! NKG2C_HUMAN relationship: location_of CCO:B0036600 ! NKG2A_HUMAN relationship: location_of CCO:B0036631 ! LRRN2_HUMAN relationship: location_of CCO:B0037083 ! RXFP2_HUMAN relationship: location_of CCO:B0037085 ! RXFP1_HUMAN relationship: location_of CCO:B0037087 ! Q3KU23_HUMAN relationship: location_of CCO:B0037130 ! DJB12_HUMAN relationship: location_of CCO:B0037229 ! PE2R3_HUMAN relationship: location_of CCO:B0037398 ! PXK_HUMAN relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0038260 ! 5HT2C_HUMAN relationship: location_of CCO:B0038262 ! HRH2_HUMAN relationship: location_of CCO:B0038263 ! ADA1B_HUMAN relationship: location_of CCO:B0038265 ! ADA1D_HUMAN relationship: location_of CCO:B0038266 ! 5HT1D_HUMAN relationship: location_of CCO:B0038267 ! ADA2B_HUMAN relationship: location_of CCO:B0038438 ! RB11A_HUMAN relationship: location_of CCO:B0038563 ! ADA11_HUMAN relationship: location_of CCO:B0038590 ! Q6IFJ9_HUMAN relationship: location_of CCO:B0038591 ! Q8NG79_HUMAN relationship: location_of CCO:B0038592 ! OR6M1_HUMAN relationship: location_of CCO:B0038594 ! A6NJJ1_HUMAN relationship: location_of CCO:B0038734 ! DPP4_HUMAN relationship: location_of CCO:B0038854 ! FZD5_HUMAN relationship: location_of CCO:B0038855 ! FZD1_HUMAN relationship: location_of CCO:B0038856 ! FZD7_HUMAN relationship: location_of CCO:B0038857 ! FZD2_HUMAN relationship: location_of CCO:B0038861 ! FZD9_HUMAN relationship: location_of CCO:B0038863 ! FZD8_HUMAN relationship: location_of CCO:B0038865 ! FZD10_HUMAN relationship: location_of CCO:B0038878 ! CSF1_HUMAN relationship: location_of CCO:B0038926 ! TRPV4_HUMAN relationship: location_of CCO:B0038991 ! CSTN1_HUMAN relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0039298 ! ADA1A_HUMAN-Phosphoserine215 relationship: location_of CCO:B0039301 ! ADA22_HUMAN-Phosphoserine834 relationship: location_of CCO:B0039339 ! CAP2_HUMAN-Phosphoserine301 relationship: location_of CCO:B0039348 ! CCL13_HUMAN-acid24 relationship: location_of CCO:B0039349 ! CCL2_HUMAN-Pyrrolidone carboxylic acid24 relationship: location_of CCO:B0039351 ! CCL8_HUMAN-Pyrrolidone carboxylic acid24 relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: location_of CCO:B0039507 ! MARK2_HUMAN-Phosphothreonine208 relationship: location_of CCO:B0039518 ! MAST1_HUMAN-Phosphoserine161 relationship: location_of CCO:B0039581 ! PGFRA_HUMAN-Phosphotyrosine720 relationship: location_of CCO:B0039588 ! PLS1_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0039596 ! PREX1_HUMAN-Phosphoserine436 relationship: location_of CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: location_of CCO:B0039613 ! RB11B_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0039618 ! RGPS2_HUMAN-Phosphoserine343 relationship: location_of CCO:B0039642 ! RRBP1_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0039664 ! SYUA_HUMAN-Phosphoserine87 relationship: location_of CCO:B0039677 ! TGFR1_HUMAN-Phosphoserine191 relationship: location_of CCO:B0039687 ! TRPV1_HUMAN-Phosphoserine775 relationship: location_of CCO:B0039914 ! TR13B_HUMAN relationship: location_of CCO:B0039936 ! RHEB_HUMAN-Cysteine methyl ester181 relationship: location_of CCO:B0039988 ! PP16A_HUMAN-Phosphotyrosine434 relationship: location_of CCO:B0040018 ! GNPAT_HUMAN relationship: location_of CCO:B0040086 ! SYT17_HUMAN relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0040520 ! A9UJN9_HUMAN relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0040684 ! REBL1_HUMAN relationship: location_of CCO:B0040688 ! RPN1_HUMAN relationship: location_of CCO:B0041173 ! RASH_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041279 ! TM90B_HUMAN relationship: location_of CCO:B0041371 ! RHG15_HUMAN relationship: location_of CCO:B0041523 ! ANK1_HUMAN relationship: location_of CCO:B0041800 ! CAN1_HUMAN relationship: location_of CCO:B0041821 ! CAN2_HUMAN relationship: location_of CCO:B0041921 ! B0UXY8_HUMAN relationship: location_of CCO:B0041924 ! Q8NHA5_HUMAN relationship: location_of CCO:B0041925 ! B0UXY7_HUMAN relationship: location_of CCO:B0041927 ! A6NNW8_HUMAN relationship: location_of CCO:B0042221 ! A8MT20_HUMAN relationship: location_of CCO:B0042222 ! GRM3_HUMAN relationship: location_of CCO:B0042225 ! GRM4_HUMAN relationship: location_of CCO:B0042226 ! Q8N0Z0_HUMAN relationship: location_of CCO:B0042227 ! GRM7_HUMAN relationship: location_of CCO:B0042228 ! A4D0Y3_HUMAN relationship: location_of CCO:B0042229 ! Q8NHA9_HUMAN relationship: location_of CCO:B0042230 ! GRM5_HUMAN relationship: location_of CCO:B0042237 ! Q86YG3_HUMAN relationship: location_of CCO:B0042238 ! Q6J164_HUMAN relationship: location_of CCO:B0042239 ! GRM2_HUMAN relationship: location_of CCO:B0042241 ! GRM8_HUMAN relationship: location_of CCO:B0042244 ! GRM6_HUMAN relationship: location_of CCO:B0042246 ! A8K1R9_HUMAN relationship: location_of CCO:B0042251 ! Q6ZMQ2_HUMAN relationship: location_of CCO:B0042255 ! Q59HC2_HUMAN relationship: location_of CCO:B0042293 ! ACHG_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0042813 ! IL2RB_HUMAN relationship: location_of CCO:B0042830 ! FCERA_HUMAN relationship: location_of CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 relationship: location_of CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: location_of CCO:B0043358 ! RHG27_HUMAN-Phosphotyrosine228 relationship: location_of CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 relationship: location_of CCO:B0043374 ! RTN4_HUMAN-Phosphoserine863 relationship: location_of CCO:B0043424 ! KCD17_HUMAN relationship: location_of CCO:B0043430 ! RNF5_HUMAN relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0043445 ! HEXA_HUMAN relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0043552 ! PI51A_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0043817 ! NGX6_HUMAN relationship: location_of CCO:B0043824 ! IL12B_HUMAN relationship: location_of CCO:B0043833 ! SC5A8_HUMAN relationship: location_of CCO:B0043866 ! LPAR2_HUMAN relationship: location_of CCO:B0043867 ! LPAR4_HUMAN relationship: location_of CCO:B0048252 ! EFNB1_HUMAN-Phosphotyrosine317 relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0048304 ! K1549_HUMAN-Phosphoserine1319 relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0048898 ! RGPS1_HUMAN relationship: location_of CCO:B0048923 ! B1AKC9_HUMAN relationship: location_of CCO:B0048954 ! IL31R_HUMAN relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0049157 ! PAR4_HUMAN relationship: location_of CCO:B0049161 ! PAR2_HUMAN relationship: location_of CCO:B0049421 ! KCNQ1_HUMAN relationship: location_of CCO:B0049452 ! NK2R_HUMAN relationship: location_of CCO:B0049455 ! NK3R_HUMAN relationship: location_of CCO:B0049457 ! NK1R_HUMAN relationship: location_of CCO:B0049552 ! A9YLN5_HUMAN relationship: location_of CCO:B0049553 ! A9YLN4_HUMAN relationship: location_of CCO:B0049556 ! Q5H8Y1_HUMAN relationship: location_of CCO:B0049557 ! A9YLN6_HUMAN relationship: location_of CCO:B0049558 ! HG2A_HUMAN relationship: location_of CCO:B0049576 ! NRG1_HUMAN relationship: location_of CCO:B0049698 ! CLD7_HUMAN relationship: location_of CCO:B0049806 ! OR8H1_HUMAN relationship: location_of CCO:B0049809 ! A8MYY4_HUMAN relationship: location_of CCO:B0049812 ! A8MYM5_HUMAN relationship: location_of CCO:B0049813 ! OR8B4_HUMAN relationship: location_of CCO:B0049814 ! OR8H3_HUMAN relationship: location_of CCO:B0049816 ! OR8H2_HUMAN relationship: location_of CCO:B0049817 ! OR5MB_HUMAN relationship: location_of CCO:B0049915 ! RAMP3_HUMAN relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0050006 ! CD72_HUMAN relationship: location_of CCO:B0050188 ! Q4VAK1_HUMAN relationship: location_of CCO:B0050189 ! ITAM_HUMAN relationship: location_of CCO:B0050190 ! ITAD_HUMAN relationship: location_of CCO:B0050191 ! ITA11_HUMAN relationship: location_of CCO:B0050192 ! ITAX_HUMAN relationship: location_of CCO:B0050193 ! Q59H14_HUMAN relationship: location_of CCO:B0050195 ! Q8TES5_HUMAN relationship: location_of CCO:B0050196 ! ITA2_HUMAN relationship: location_of CCO:B0050197 ! A8MPT3_HUMAN relationship: location_of CCO:B0050198 ! A8MTX2_HUMAN relationship: location_of CCO:B0050199 ! Q96HB1_HUMAN relationship: location_of CCO:B0050200 ! A8MZ95_HUMAN relationship: location_of CCO:B0050202 ! ITAL_HUMAN relationship: location_of CCO:B0050612 ! NCKP1_HUMAN relationship: location_of CCO:B0050753 ! OPRD_HUMAN relationship: location_of CCO:B0050755 ! SSR2_HUMAN relationship: location_of CCO:B0050758 ! OPRK_HUMAN relationship: location_of CCO:B0050764 ! NPBW2_HUMAN relationship: location_of CCO:B0050781 ! OPRX_HUMAN relationship: location_of CCO:B0050782 ! NPBW1_HUMAN relationship: location_of CCO:B0050788 ! SSR1_HUMAN relationship: location_of CCO:B0050793 ! SSR4_HUMAN relationship: location_of CCO:B0050794 ! SSR3_HUMAN relationship: location_of CCO:B0050997 ! MFN2_HUMAN relationship: location_of CCO:B0051232 ! CLPT1_HUMAN relationship: location_of CCO:B0051353 ! GBRL1_HUMAN relationship: location_of CCO:B0051370 ! FIBP_HUMAN relationship: location_of CCO:B0051475 ! MOT3_HUMAN relationship: location_of CCO:B0051832 ! Q8WU57_HUMAN relationship: location_of CCO:B0051877 ! OR8D2_HUMAN relationship: location_of CCO:B0051880 ! OR8G1_HUMAN relationship: location_of CCO:B0051882 ! OR8G2_HUMAN relationship: location_of CCO:B0051883 ! OR8U9_HUMAN relationship: location_of CCO:B0051887 ! O5AK2_HUMAN relationship: location_of CCO:B0051892 ! OR8U8_HUMAN relationship: location_of CCO:B0051893 ! O5AP2_HUMAN relationship: location_of CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0052321 ! CEAM6_HUMAN-Phosphoserine243 relationship: location_of CCO:B0052500 ! IRS4_HUMAN-Phosphotyrosine921 relationship: location_of CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 relationship: location_of CCO:B0052705 ! ROS_HUMAN-Phosphotyrosine2114 relationship: location_of CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: location_of CCO:B0052794 ! SSR5_HUMAN-Phosphoserine325 relationship: location_of CCO:B0052851 ! TMCC2_HUMAN-Phosphoserine481 relationship: location_of CCO:B0053696 ! A0A502_HUMAN relationship: location_of CCO:B0053705 ! RHG10_HUMAN relationship: location_of CCO:B0053724 ! A2BDZ0_HUMAN relationship: location_of CCO:B0053725 ! A2BDZ2_HUMAN relationship: location_of CCO:B0053726 ! A2BEC2_HUMAN relationship: location_of CCO:B0053727 ! A2BF33_HUMAN relationship: location_of CCO:B0053728 ! A2BF34_HUMAN relationship: location_of CCO:B0053742 ! OR2M5_HUMAN relationship: location_of CCO:B0053752 ! RAB19_HUMAN relationship: location_of CCO:B0053754 ! A4D225_HUMAN relationship: location_of CCO:B0053758 ! A4D2G2_HUMAN relationship: location_of CCO:B0053759 ! O2A25_HUMAN relationship: location_of CCO:B0053761 ! A4D2P2_HUMAN relationship: location_of CCO:B0053765 ! A4FVB3_HUMAN relationship: location_of CCO:B0053781 ! A6MW40_HUMAN relationship: location_of CCO:B0053783 ! A6NC31_HUMAN relationship: location_of CCO:B0053784 ! A6NC89_HUMAN relationship: location_of CCO:B0053786 ! O6C74_HUMAN relationship: location_of CCO:B0053788 ! O14I1_HUMAN relationship: location_of CCO:B0053793 ! O6C68_HUMAN relationship: location_of CCO:B0053800 ! A6NE11_HUMAN relationship: location_of CCO:B0053805 ! A6NE96_HUMAN relationship: location_of CCO:B0053813 ! A6NF12_HUMAN relationship: location_of CCO:B0053816 ! OR6C6_HUMAN relationship: location_of CCO:B0053817 ! OR2W5_HUMAN relationship: location_of CCO:B0053824 ! A6NFR0_HUMAN relationship: location_of CCO:B0053827 ! A6NG39_HUMAN relationship: location_of CCO:B0053834 ! A6NGT9_HUMAN relationship: location_of CCO:B0053835 ! O51F1_HUMAN relationship: location_of CCO:B0053836 ! OR2T8_HUMAN relationship: location_of CCO:B0053842 ! A6NH69_HUMAN relationship: location_of CCO:B0053845 ! O4C46_HUMAN relationship: location_of CCO:B0053861 ! A6NIH4_HUMAN relationship: location_of CCO:B0053862 ! O6C70_HUMAN relationship: location_of CCO:B0053863 ! A6NIQ0_HUMAN relationship: location_of CCO:B0053866 ! A6NJ05_HUMAN relationship: location_of CCO:B0053869 ! A6NJ96_HUMAN relationship: location_of CCO:B0053875 ! O6C65_HUMAN relationship: location_of CCO:B0053886 ! A6NKK7_HUMAN relationship: location_of CCO:B0053887 ! A6NKM1_HUMAN relationship: location_of CCO:B0053890 ! O6C75_HUMAN relationship: location_of CCO:B0053892 ! OR5BL_HUMAN relationship: location_of CCO:B0053893 ! A6NL96_HUMAN relationship: location_of CCO:B0053897 ! A6NLH6_HUMAN relationship: location_of CCO:B0053902 ! O2AG2_HUMAN relationship: location_of CCO:B0053904 ! O6C76_HUMAN relationship: location_of CCO:B0053908 ! O52A4_HUMAN relationship: location_of CCO:B0053910 ! O4C45_HUMAN relationship: location_of CCO:B0053911 ! A6NN09_HUMAN relationship: location_of CCO:B0053914 ! O2AT4_HUMAN relationship: location_of CCO:B0053939 ! A6QRH2_HUMAN relationship: location_of CCO:B0053959 ! A8K2Y6_HUMAN relationship: location_of CCO:B0053960 ! A8K305_HUMAN relationship: location_of CCO:B0053966 ! A8K4E4_HUMAN relationship: location_of CCO:B0053973 ! A8K6W1_HUMAN relationship: location_of CCO:B0053978 ! A8K8D4_HUMAN relationship: location_of CCO:B0054001 ! A8MQV3_HUMAN relationship: location_of CCO:B0054018 ! A8MSZ9_HUMAN relationship: location_of CCO:B0054024 ! A8MTE1_HUMAN relationship: location_of CCO:B0054037 ! A8MU07_HUMAN relationship: location_of CCO:B0054039 ! A8MUF8_HUMAN relationship: location_of CCO:B0054041 ! A8MUH3_HUMAN relationship: location_of CCO:B0054042 ! A8MUM9_HUMAN relationship: location_of CCO:B0054043 ! A8MUR1_HUMAN relationship: location_of CCO:B0054045 ! A8MUS4_HUMAN relationship: location_of CCO:B0054049 ! A8MUW4_HUMAN relationship: location_of CCO:B0054050 ! A8MUY8_HUMAN relationship: location_of CCO:B0054052 ! A8MV06_HUMAN relationship: location_of CCO:B0054058 ! A8MVF0_HUMAN relationship: location_of CCO:B0054061 ! A8MVM5_HUMAN relationship: location_of CCO:B0054064 ! A8MVP6_HUMAN relationship: location_of CCO:B0054066 ! A8MVV5_HUMAN relationship: location_of CCO:B0054067 ! A8MVW4_HUMAN relationship: location_of CCO:B0054079 ! A8MWG5_HUMAN relationship: location_of CCO:B0054080 ! A8MWI1_HUMAN relationship: location_of CCO:B0054082 ! A8MWS2_HUMAN relationship: location_of CCO:B0054086 ! A8MX01_HUMAN relationship: location_of CCO:B0054091 ! A8MX59_HUMAN relationship: location_of CCO:B0054093 ! A8MX88_HUMAN relationship: location_of CCO:B0054094 ! A8MXA6_HUMAN relationship: location_of CCO:B0054095 ! A8MXE9_HUMAN relationship: location_of CCO:B0054097 ! A8MXI2_HUMAN relationship: location_of CCO:B0054098 ! A8MXI6_HUMAN relationship: location_of CCO:B0054100 ! A8MXL5_HUMAN relationship: location_of CCO:B0054104 ! A8MXU4_HUMAN relationship: location_of CCO:B0054108 ! A8MXZ2_HUMAN relationship: location_of CCO:B0054109 ! A8MXZ4_HUMAN relationship: location_of CCO:B0054111 ! A8MY27_HUMAN relationship: location_of CCO:B0054116 ! A8MY83_HUMAN relationship: location_of CCO:B0054135 ! A8MZ16_HUMAN relationship: location_of CCO:B0054136 ! A8MZ46_HUMAN relationship: location_of CCO:B0054142 ! A8MZG7_HUMAN relationship: location_of CCO:B0054185 ! B0S882_HUMAN relationship: location_of CCO:B0054186 ! B0UY34_HUMAN relationship: location_of CCO:B0054189 ! B0V1T2_HUMAN relationship: location_of CCO:B0054191 ! B0V1X5_HUMAN relationship: location_of CCO:B0054198 ! B0ZBD2_HUMAN relationship: location_of CCO:B0054199 ! B0ZBD3_HUMAN relationship: location_of CCO:B0054200 ! B0ZBD8_HUMAN relationship: location_of CCO:B0054225 ! B1AK49_HUMAN relationship: location_of CCO:B0054241 ! B1ALU1_HUMAN relationship: location_of CCO:B0054242 ! B1ALU2_HUMAN relationship: location_of CCO:B0054243 ! B1ALU3_HUMAN relationship: location_of CCO:B0054244 ! B1ALU4_HUMAN relationship: location_of CCO:B0054245 ! B1ALU5_HUMAN relationship: location_of CCO:B0054246 ! B1ALU6_HUMAN relationship: location_of CCO:B0054248 ! B1ALY0_HUMAN relationship: location_of CCO:B0054251 ! B1AMA2_HUMAN relationship: location_of CCO:B0054259 ! B1AN12_HUMAN relationship: location_of CCO:B0054267 ! B1AP22_HUMAN relationship: location_of CCO:B0054278 ! B1AWB3_HUMAN relationship: location_of CCO:B0054279 ! B1AWB4_HUMAN relationship: location_of CCO:B0054280 ! B1AWB6_HUMAN relationship: location_of CCO:B0054281 ! B1AWB7_HUMAN relationship: location_of CCO:B0054291 ! GPR25_HUMAN relationship: location_of CCO:B0054300 ! RHOD_HUMAN relationship: location_of CCO:B0054302 ! SIRB1_HUMAN relationship: location_of CCO:B0054306 ! GPR31_HUMAN relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054316 ! P2Y10_HUMAN relationship: location_of CCO:B0054317 ! PDE2A_HUMAN relationship: location_of CCO:B0054318 ! CCRL2_HUMAN relationship: location_of CCO:B0054320 ! DNM1L_HUMAN relationship: location_of CCO:B0054321 ! GFRA2_HUMAN relationship: location_of CCO:B0054322 ! LST1_HUMAN relationship: location_of CCO:B0054330 ! KRIT1_HUMAN relationship: location_of CCO:B0054333 ! CXCR6_HUMAN relationship: location_of CCO:B0054335 ! CCBP2_HUMAN relationship: location_of CCO:B0054336 ! PODXL_HUMAN relationship: location_of CCO:B0054342 ! ACACB_HUMAN relationship: location_of CCO:B0054344 ! LPP1_HUMAN relationship: location_of CCO:B0054346 ! NRG2_HUMAN relationship: location_of CCO:B0054347 ! SOCS7_HUMAN relationship: location_of CCO:B0054348 ! BAI1_HUMAN relationship: location_of CCO:B0054353 ! OR7AH_HUMAN relationship: location_of CCO:B0054356 ! GBGT2_HUMAN relationship: location_of CCO:B0054357 ! BORG1_HUMAN relationship: location_of CCO:B0054360 ! GP171_HUMAN relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0054365 ! EI24_HUMAN relationship: location_of CCO:B0054367 ! PTGES_HUMAN relationship: location_of CCO:B0054368 ! O14694_HUMAN relationship: location_of CCO:B0054370 ! ITBP1_HUMAN relationship: location_of CCO:B0054373 ! TR10B_HUMAN relationship: location_of CCO:B0054375 ! TNF11_HUMAN relationship: location_of CCO:B0054378 ! TAAR5_HUMAN relationship: location_of CCO:B0054379 ! RASM_HUMAN relationship: location_of CCO:B0054383 ! FFAR3_HUMAN relationship: location_of CCO:B0054386 ! MGST3_HUMAN relationship: location_of CCO:B0054391 ! GIPC1_HUMAN relationship: location_of CCO:B0054394 ! RAB7L_HUMAN relationship: location_of CCO:B0054403 ! MCF2L_HUMAN relationship: location_of CCO:B0054417 ! GP182_HUMAN relationship: location_of CCO:B0054419 ! CLIC2_HUMAN relationship: location_of CCO:B0054420 ! NPHP1_HUMAN relationship: location_of CCO:B0054432 ! GPR37_HUMAN relationship: location_of CCO:B0054440 ! INSI1_HUMAN relationship: location_of CCO:B0054444 ! GPR42_HUMAN relationship: location_of CCO:B0054448 ! FFAR2_HUMAN relationship: location_of CCO:B0054451 ! PLXB1_HUMAN relationship: location_of CCO:B0054454 ! NDUS4_HUMAN relationship: location_of CCO:B0054459 ! MTLR_HUMAN relationship: location_of CCO:B0054460 ! GPR39_HUMAN relationship: location_of CCO:B0054478 ! RASL2_HUMAN relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0054484 ! TNF12_HUMAN relationship: location_of CCO:B0054485 ! AT8B1_HUMAN relationship: location_of CCO:B0054490 ! TNF14_HUMAN relationship: location_of CCO:B0054491 ! FRS3_HUMAN relationship: location_of CCO:B0054493 ! AKA10_HUMAN relationship: location_of CCO:B0054498 ! GALR2_HUMAN relationship: location_of CCO:B0054499 ! SPY1_HUMAN relationship: location_of CCO:B0054500 ! SPY3_HUMAN relationship: location_of CCO:B0054503 ! OX2R_HUMAN relationship: location_of CCO:B0054505 ! O43627_HUMAN relationship: location_of CCO:B0054508 ! TSN6_HUMAN relationship: location_of CCO:B0054511 ! AKA7A_HUMAN relationship: location_of CCO:B0054518 ! OR1F1_HUMAN relationship: location_of CCO:B0054520 ! MCAT_HUMAN relationship: location_of CCO:B0054528 ! OR2T1_HUMAN relationship: location_of CCO:B0054537 ! GBG7_HUMAN relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: location_of CCO:B0054549 ! FZD6_HUMAN relationship: location_of CCO:B0054552 ! O10H2_HUMAN relationship: location_of CCO:B0054553 ! O10H3_HUMAN relationship: location_of CCO:B0054554 ! O60411_HUMAN relationship: location_of CCO:B0054555 ! OR7C2_HUMAN relationship: location_of CCO:B0054556 ! FADS1_HUMAN relationship: location_of CCO:B0054558 ! OR1I1_HUMAN relationship: location_of CCO:B0054560 ! O60466_HUMAN relationship: location_of CCO:B0054561 ! PLXC1_HUMAN relationship: location_of CCO:B0054569 ! TLR5_HUMAN relationship: location_of CCO:B0054570 ! GFRA3_HUMAN relationship: location_of CCO:B0054573 ! FAIM3_HUMAN relationship: location_of CCO:B0054576 ! GALR3_HUMAN relationship: location_of CCO:B0054587 ! RAMP1_HUMAN relationship: location_of CCO:B0054589 ! NSMA_HUMAN relationship: location_of CCO:B0054592 ! LIRA1_HUMAN relationship: location_of CCO:B0054594 ! LIRB5_HUMAN relationship: location_of CCO:B0054599 ! PLXA2_HUMAN relationship: location_of CCO:B0054601 ! MTG16_HUMAN relationship: location_of CCO:B0054602 ! ROCK2_HUMAN relationship: location_of CCO:B0054605 ! ICOSL_HUMAN relationship: location_of CCO:B0054609 ! NPHP4_HUMAN relationship: location_of CCO:B0054613 ! PX11A_HUMAN relationship: location_of CCO:B0054618 ! PDCD6_HUMAN relationship: location_of CCO:B0054630 ! GPR32_HUMAN relationship: location_of CCO:B0054636 ! USH2A_HUMAN relationship: location_of CCO:B0054640 ! LGR5_HUMAN relationship: location_of CCO:B0054643 ! GPC4_HUMAN relationship: location_of CCO:B0054644 ! NDUS3_HUMAN relationship: location_of CCO:B0054647 ! TNR21_HUMAN relationship: location_of CCO:B0054652 ! ITA10_HUMAN relationship: location_of CCO:B0054663 ! P3C2G_HUMAN relationship: location_of CCO:B0054666 ! RHBL1_HUMAN relationship: location_of CCO:B0054667 ! RENR_HUMAN relationship: location_of CCO:B0054672 ! LECT1_HUMAN relationship: location_of CCO:B0054674 ! TNF13_HUMAN relationship: location_of CCO:B0054678 ! RGS9_HUMAN relationship: location_of CCO:B0054684 ! OR2B3_HUMAN relationship: location_of CCO:B0054685 ! OR2J3_HUMAN relationship: location_of CCO:B0054686 ! OR2J2_HUMAN relationship: location_of CCO:B0054688 ! NCTR1_HUMAN relationship: location_of CCO:B0054694 ! OR7C1_HUMAN relationship: location_of CCO:B0054695 ! OR7AA_HUMAN relationship: location_of CCO:B0054715 ! OR2F2_HUMAN relationship: location_of CCO:B0054716 ! O4F21_HUMAN relationship: location_of CCO:B0054717 ! OR2A4_HUMAN relationship: location_of CCO:B0054718 ! KCNK2_HUMAN relationship: location_of CCO:B0054727 ! S1PR2_HUMAN relationship: location_of CCO:B0054731 ! ZFPL1_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054736 ! OR5F1_HUMAN relationship: location_of CCO:B0054737 ! OR6A2_HUMAN relationship: location_of CCO:B0054740 ! I18RA_HUMAN relationship: location_of CCO:B0054741 ! KCNH1_HUMAN relationship: location_of CCO:B0054745 ! TNKS1_HUMAN relationship: location_of CCO:B0054748 ! MPZL1_HUMAN relationship: location_of CCO:B0054752 ! OR2C1_HUMAN relationship: location_of CCO:B0054757 ! RPGF3_HUMAN relationship: location_of CCO:B0054759 ! CNIH_HUMAN relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: location_of CCO:B0054767 ! LPHN2_HUMAN relationship: location_of CCO:B0054768 ! VNN1_HUMAN relationship: location_of CCO:B0054769 ! O95499_HUMAN relationship: location_of CCO:B0054780 ! NTR2_HUMAN relationship: location_of CCO:B0054781 ! ECEL1_HUMAN relationship: location_of CCO:B0054785 ! RAB3D_HUMAN relationship: location_of CCO:B0054792 ! RAB36_HUMAN relationship: location_of CCO:B0054793 ! TBCD8_HUMAN relationship: location_of CCO:B0054794 ! GPR75_HUMAN relationship: location_of CCO:B0054798 ! CLIC3_HUMAN relationship: location_of CCO:B0054804 ! OR2H2_HUMAN relationship: location_of CCO:B0054807 ! NCTR2_HUMAN relationship: location_of CCO:B0054811 ! BY55_HUMAN relationship: location_of CCO:B0054812 ! IGSF6_HUMAN relationship: location_of CCO:B0054813 ! S1PR4_HUMAN relationship: location_of CCO:B0054820 ! PX11B_HUMAN relationship: location_of CCO:B0054828 ! RENI_HUMAN relationship: location_of CCO:B0054856 ! CD8A_HUMAN relationship: location_of CCO:B0054858 ! 2B32_HUMAN relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0054870 ! CO9_HUMAN relationship: location_of CCO:B0054879 ! OPSB_HUMAN relationship: location_of CCO:B0054880 ! OPSR_HUMAN relationship: location_of CCO:B0054881 ! OPSG_HUMAN relationship: location_of CCO:B0054888 ! MAS_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054915 ! HEXB_HUMAN relationship: location_of CCO:B0054916 ! CD3E_HUMAN relationship: location_of CCO:B0054917 ! UROM_HUMAN relationship: location_of CCO:B0054921 ! TNR16_HUMAN relationship: location_of CCO:B0054925 ! MCR_HUMAN relationship: location_of CCO:B0054928 ! CD14_HUMAN relationship: location_of CCO:B0054929 ! ADRB1_HUMAN relationship: location_of CCO:B0054933 ! IL6RA_HUMAN relationship: location_of CCO:B0054934 ! 5HT1A_HUMAN relationship: location_of CCO:B0054935 ! ABHD2_HUMAN relationship: location_of CCO:B0054937 ! ADA2A_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0054941 ! DOPO_HUMAN relationship: location_of CCO:B0054946 ! CD7_HUMAN relationship: location_of CCO:B0054950 ! TACD2_HUMAN relationship: location_of CCO:B0054951 ! IFI6_HUMAN relationship: location_of CCO:B0054953 ! RB40L_HUMAN relationship: location_of CCO:B0054955 ! OR4A8_HUMAN relationship: location_of CCO:B0054956 ! O5AL1_HUMAN relationship: location_of CCO:B0054957 ! OR4Q2_HUMAN relationship: location_of CCO:B0054958 ! OR5G3_HUMAN relationship: location_of CCO:B0054959 ! O10J4_HUMAN relationship: location_of CCO:B0054960 ! OR4E1_HUMAN relationship: location_of CCO:B0054961 ! O52Z1_HUMAN relationship: location_of CCO:B0054964 ! OR9G9_HUMAN relationship: location_of CCO:B0054975 ! PTPRF_HUMAN relationship: location_of CCO:B0054983 ! CD8B_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0054988 ! RALA_HUMAN relationship: location_of CCO:B0054989 ! RALB_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0054995 ! CD20_HUMAN relationship: location_of CCO:B0055006 ! ACE_HUMAN relationship: location_of CCO:B0055019 ! 2B14_HUMAN relationship: location_of CCO:B0055020 ! ADRB3_HUMAN relationship: location_of CCO:B0055023 ! HCLS1_HUMAN relationship: location_of CCO:B0055024 ! DRD2_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055039 ! AREG_HUMAN relationship: location_of CCO:B0055047 ! LEUK_HUMAN relationship: location_of CCO:B0055051 ! EPB42_HUMAN relationship: location_of CCO:B0055053 ! PRLR_HUMAN relationship: location_of CCO:B0055054 ! TSHR_HUMAN relationship: location_of CCO:B0055084 ! TMM11_HUMAN relationship: location_of CCO:B0055086 ! ANPRC_HUMAN relationship: location_of CCO:B0055092 ! EGLN_HUMAN relationship: location_of CCO:B0055103 ! LAG3_HUMAN relationship: location_of CCO:B0055104 ! ADA2C_HUMAN relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0055108 ! CD53_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055131 ! MAL_HUMAN relationship: location_of CCO:B0055133 ! CNR1_HUMAN relationship: location_of CCO:B0055135 ! SCF_HUMAN relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0055138 ! TA2R_HUMAN relationship: location_of CCO:B0055139 ! DRD4_HUMAN relationship: location_of CCO:B0055140 ! DRD5_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055145 ! ENPP1_HUMAN relationship: location_of CCO:B0055147 ! FGFR4_HUMAN relationship: location_of CCO:B0055152 ! LSHR_HUMAN relationship: location_of CCO:B0055154 ! ITA6_HUMAN relationship: location_of CCO:B0055157 ! PTPRD_HUMAN relationship: location_of CCO:B0055158 ! PTPRG_HUMAN relationship: location_of CCO:B0055160 ! TNFL4_HUMAN relationship: location_of CCO:B0055167 ! CPT2_HUMAN relationship: location_of CCO:B0055172 ! AKAP5_HUMAN relationship: location_of CCO:B0055175 ! CXCR1_HUMAN relationship: location_of CCO:B0055177 ! CD24_HUMAN relationship: location_of CCO:B0055178 ! FPR3_HUMAN relationship: location_of CCO:B0055179 ! FPR2_HUMAN relationship: location_of CCO:B0055180 ! ARBK1_HUMAN relationship: location_of CCO:B0055181 ! PTAFR_HUMAN relationship: location_of CCO:B0055182 ! CXCR7_HUMAN relationship: location_of CCO:B0055187 ! NPY1R_HUMAN relationship: location_of CCO:B0055188 ! TNR5_HUMAN relationship: location_of CCO:B0055189 ! ITA3_HUMAN relationship: location_of CCO:B0055191 ! AMFR1_HUMAN relationship: location_of CCO:B0055192 ! NKG2D_HUMAN relationship: location_of CCO:B0055193 ! CD27_HUMAN relationship: location_of CCO:B0055197 ! 5HT1B_HUMAN relationship: location_of CCO:B0055198 ! 5HT2A_HUMAN relationship: location_of CCO:B0055201 ! NMBR_HUMAN relationship: location_of CCO:B0055205 ! 5HT1E_HUMAN relationship: location_of CCO:B0055207 ! CD38_HUMAN relationship: location_of CCO:B0055210 ! AA2AR_HUMAN relationship: location_of CCO:B0055211 ! AA2BR_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0055218 ! BKRB2_HUMAN relationship: location_of CCO:B0055219 ! V2R_HUMAN relationship: location_of CCO:B0055220 ! TSPO_HUMAN relationship: location_of CCO:B0055221 ! AA1R_HUMAN relationship: location_of CCO:B0055222 ! GRPR_HUMAN relationship: location_of CCO:B0055223 ! AGTR1_HUMAN relationship: location_of CCO:B0055224 ! OXYR_HUMAN relationship: location_of CCO:B0055226 ! 5HT1F_HUMAN relationship: location_of CCO:B0055227 ! OR1E1_HUMAN relationship: location_of CCO:B0055228 ! O10J1_HUMAN relationship: location_of CCO:B0055229 ! GNRHR_HUMAN relationship: location_of CCO:B0055230 ! CALCR_HUMAN relationship: location_of CCO:B0055231 ! NTR1_HUMAN relationship: location_of CCO:B0055247 ! FCG2B_HUMAN relationship: location_of CCO:B0055251 ! CCKAR_HUMAN relationship: location_of CCO:B0055252 ! GASR_HUMAN relationship: location_of CCO:B0055256 ! CCR1_HUMAN relationship: location_of CCO:B0055257 ! BRS3_HUMAN relationship: location_of CCO:B0055258 ! CCR7_HUMAN relationship: location_of CCO:B0055260 ! CXCR5_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055262 ! CD70_HUMAN relationship: location_of CCO:B0055263 ! TNFL8_HUMAN relationship: location_of CCO:B0055265 ! LSP1_HUMAN relationship: location_of CCO:B0055268 ! CD80_HUMAN relationship: location_of CCO:B0055272 ! 5HT7R_HUMAN relationship: location_of CCO:B0055273 ! CNR2_HUMAN relationship: location_of CCO:B0055274 ! TRFR_HUMAN relationship: location_of CCO:B0055275 ! PE2R1_HUMAN relationship: location_of CCO:B0055276 ! CRFR1_HUMAN relationship: location_of CCO:B0055288 ! PE2R4_HUMAN relationship: location_of CCO:B0055289 ! MAS1L_HUMAN relationship: location_of CCO:B0055290 ! APJ_HUMAN relationship: location_of CCO:B0055293 ! DRD3_HUMAN relationship: location_of CCO:B0055295 ! TIE1_HUMAN relationship: location_of CCO:B0055303 ! PDE6B_HUMAN relationship: location_of CCO:B0055304 ! VGFR3_HUMAN relationship: location_of CCO:B0055305 ! VGFR2_HUMAN relationship: location_of CCO:B0055308 ! ARD1_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055313 ! TNR3_HUMAN relationship: location_of CCO:B0055318 ! V1AR_HUMAN relationship: location_of CCO:B0055325 ! ADCY8_HUMAN relationship: location_of CCO:B0055327 ! TPOR_HUMAN relationship: location_of CCO:B0055328 ! CD79B_HUMAN relationship: location_of CCO:B0055335 ! CASR_HUMAN relationship: location_of CCO:B0055338 ! P2RY2_HUMAN relationship: location_of CCO:B0055340 ! TNFL9_HUMAN relationship: location_of CCO:B0055341 ! PACR_HUMAN relationship: location_of CCO:B0055342 ! VIPR2_HUMAN relationship: location_of CCO:B0055343 ! 5HT2B_HUMAN relationship: location_of CCO:B0055346 ! CD86_HUMAN relationship: location_of CCO:B0055354 ! I12R1_HUMAN relationship: location_of CCO:B0055355 ! LIFR_HUMAN relationship: location_of CCO:B0055356 ! NSG1_HUMAN relationship: location_of CCO:B0055357 ! GUC1A_HUMAN relationship: location_of CCO:B0055358 ! PF2R_HUMAN relationship: location_of CCO:B0055359 ! PE2R2_HUMAN relationship: location_of CCO:B0055361 ! GRK6_HUMAN relationship: location_of CCO:B0055367 ! P2RY5_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055372 ! GPR3_HUMAN relationship: location_of CCO:B0055373 ! GPR1_HUMAN relationship: location_of CCO:B0055374 ! XCR1_HUMAN relationship: location_of CCO:B0055378 ! BKRB1_HUMAN relationship: location_of CCO:B0055379 ! IEX1_HUMAN relationship: location_of CCO:B0055382 ! GALR1_HUMAN relationship: location_of CCO:B0055384 ! RPGP1_HUMAN relationship: location_of CCO:B0055386 ! RGR_HUMAN relationship: location_of CCO:B0055388 ! OR3A1_HUMAN relationship: location_of CCO:B0055389 ! OR3A4_HUMAN relationship: location_of CCO:B0055390 ! OR1G1_HUMAN relationship: location_of CCO:B0055391 ! OR3A2_HUMAN relationship: location_of CCO:B0055393 ! 5HT5A_HUMAN relationship: location_of CCO:B0055395 ! V1BR_HUMAN relationship: location_of CCO:B0055398 ! TNFL6_HUMAN relationship: location_of CCO:B0055400 ! T4S4_HUMAN relationship: location_of CCO:B0055406 ! INAR2_HUMAN relationship: location_of CCO:B0055413 ! CD97_HUMAN relationship: location_of CCO:B0055414 ! G109B_HUMAN relationship: location_of CCO:B0055415 ! CAMLG_HUMAN relationship: location_of CCO:B0055418 ! NPY2R_HUMAN relationship: location_of CCO:B0055419 ! PTH2R_HUMAN relationship: location_of CCO:B0055420 ! CX3C1_HUMAN relationship: location_of CCO:B0055425 ! DGKG_HUMAN relationship: location_of CCO:B0055428 ! CXCR3_HUMAN relationship: location_of CCO:B0055429 ! PRLHR_HUMAN relationship: location_of CCO:B0055430 ! GPR15_HUMAN relationship: location_of CCO:B0055433 ! RGS6_HUMAN relationship: location_of CCO:B0055435 ! FLT3L_HUMAN relationship: location_of CCO:B0055437 ! TIG1_HUMAN relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0055442 ! AGTR2_HUMAN relationship: location_of CCO:B0055443 ! GBG4_HUMAN relationship: location_of CCO:B0055444 ! GBG10_HUMAN relationship: location_of CCO:B0055446 ! MMP14_HUMAN relationship: location_of CCO:B0055447 ! NPY4R_HUMAN relationship: location_of CCO:B0055449 ! 5HT6R_HUMAN relationship: location_of CCO:B0055455 ! TNF10_HUMAN relationship: location_of CCO:B0055456 ! LU_HUMAN relationship: location_of CCO:B0055458 ! RAB9A_HUMAN relationship: location_of CCO:B0055459 ! RAB28_HUMAN relationship: location_of CCO:B0055460 ! PDE6C_HUMAN relationship: location_of CCO:B0055468 ! P2RX1_HUMAN relationship: location_of CCO:B0055472 ! CCR3_HUMAN relationship: location_of CCO:B0055473 ! CCR4_HUMAN relationship: location_of CCO:B0055474 ! CCR5_HUMAN relationship: location_of CCO:B0055475 ! CCR6_HUMAN relationship: location_of CCO:B0055476 ! CCR8_HUMAN relationship: location_of CCO:B0055477 ! CCR9_HUMAN relationship: location_of CCO:B0055479 ! CLCN6_HUMAN relationship: location_of CCO:B0055485 ! DGKE_HUMAN relationship: location_of CCO:B0055500 ! CHIO_HUMAN relationship: location_of CCO:B0055504 ! NDST2_HUMAN relationship: location_of CCO:B0055510 ! AP2S1_HUMAN relationship: location_of CCO:B0055519 ! EMP1_HUMAN relationship: location_of CCO:B0055520 ! EMP2_HUMAN relationship: location_of CCO:B0055521 ! EMP3_HUMAN relationship: location_of CCO:B0055523 ! GEM_HUMAN relationship: location_of CCO:B0055526 ! BI1_HUMAN relationship: location_of CCO:B0055533 ! CADH4_HUMAN relationship: location_of CCO:B0055534 ! CAD13_HUMAN relationship: location_of CCO:B0055538 ! GFRA1_HUMAN relationship: location_of CCO:B0055540 ! TPTE_HUMAN relationship: location_of CCO:B0055541 ! ITA1_HUMAN relationship: location_of CCO:B0055544 ! P2RX3_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0055558 ! SYJ2B_HUMAN relationship: location_of CCO:B0055560 ! RAB25_HUMAN relationship: location_of CCO:B0055563 ! KCNKA_HUMAN relationship: location_of CCO:B0055565 ! OR2B6_HUMAN relationship: location_of CCO:B0055566 ! OR4D2_HUMAN relationship: location_of CCO:B0055567 ! O10A3_HUMAN relationship: location_of CCO:B0055568 ! O12D2_HUMAN relationship: location_of CCO:B0055573 ! RHBL3_HUMAN relationship: location_of CCO:B0055576 ! T2R12_HUMAN relationship: location_of CCO:B0055577 ! T2R38_HUMAN relationship: location_of CCO:B0055578 ! T2R39_HUMAN relationship: location_of CCO:B0055579 ! T2R41_HUMAN relationship: location_of CCO:B0055580 ! T2R43_HUMAN relationship: location_of CCO:B0055581 ! T2R44_HUMAN relationship: location_of CCO:B0055582 ! T2R45_HUMAN relationship: location_of CCO:B0055583 ! T2R46_HUMAN relationship: location_of CCO:B0055584 ! T2R47_HUMAN relationship: location_of CCO:B0055585 ! T2R48_HUMAN relationship: location_of CCO:B0055586 ! T2R49_HUMAN relationship: location_of CCO:B0055587 ! T2R50_HUMAN relationship: location_of CCO:B0055588 ! T2R60_HUMAN relationship: location_of CCO:B0055592 ! OR2B8_HUMAN relationship: location_of CCO:B0055599 ! GPR85_HUMAN relationship: location_of CCO:B0055601 ! RAB4B_HUMAN relationship: location_of CCO:B0055602 ! RAB2A_HUMAN relationship: location_of CCO:B0055614 ! GBG11_HUMAN relationship: location_of CCO:B0055625 ! POK4_HUMAN relationship: location_of CCO:B0055631 ! GBG1_HUMAN relationship: location_of CCO:B0055632 ! GBG3_HUMAN relationship: location_of CCO:B0055633 ! GBG5_HUMAN relationship: location_of CCO:B0055639 ! ACCN2_HUMAN relationship: location_of CCO:B0055645 ! X3CL1_HUMAN relationship: location_of CCO:B0055652 ! I13R1_HUMAN relationship: location_of CCO:B0055660 ! COG7_HUMAN relationship: location_of CCO:B0055669 ! VLDLR_HUMAN relationship: location_of CCO:B0055686 ! IL9R_HUMAN relationship: location_of CCO:B0055687 ! CD83_HUMAN relationship: location_of CCO:B0055688 ! IL5RA_HUMAN relationship: location_of CCO:B0055691 ! ILRL1_HUMAN relationship: location_of CCO:B0055697 ! SC6A3_HUMAN relationship: location_of CCO:B0055699 ! ROR1_HUMAN relationship: location_of CCO:B0055707 ! TNR17_HUMAN relationship: location_of CCO:B0055713 ! GHRHR_HUMAN relationship: location_of CCO:B0055715 ! TIE2_HUMAN relationship: location_of CCO:B0055721 ! GNA12_HUMAN relationship: location_of CCO:B0055723 ! UPAR_HUMAN relationship: location_of CCO:B0055724 ! PTHR1_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055740 ! PLP2_HUMAN relationship: location_of CCO:B0055756 ! Q05C50_HUMAN relationship: location_of CCO:B0055770 ! TNFC_HUMAN relationship: location_of CCO:B0055780 ! TNR9_HUMAN relationship: location_of CCO:B0055781 ! AMPE_HUMAN relationship: location_of CCO:B0055789 ! LG3BP_HUMAN relationship: location_of CCO:B0055793 ! CD47_HUMAN relationship: location_of CCO:B0055794 ! ADCY1_HUMAN relationship: location_of CCO:B0055807 ! Q09LL4_HUMAN relationship: location_of CCO:B0055813 ! Q0IJ52_HUMAN relationship: location_of CCO:B0055824 ! ADIG_HUMAN relationship: location_of CCO:B0055836 ! BST2_HUMAN relationship: location_of CCO:B0055844 ! KCNH2_HUMAN relationship: location_of CCO:B0055845 ! RB40B_HUMAN relationship: location_of CCO:B0055851 ! CNTN1_HUMAN relationship: location_of CCO:B0055856 ! PTPRJ_HUMAN relationship: location_of CCO:B0055857 ! KLRB1_HUMAN relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0055864 ! TSN31_HUMAN relationship: location_of CCO:B0055866 ! BAK2_HUMAN relationship: location_of CCO:B0055867 ! Q13027_HUMAN relationship: location_of CCO:B0055889 ! KLRD1_HUMAN relationship: location_of CCO:B0055890 ! PD2R_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055895 ! GPR17_HUMAN relationship: location_of CCO:B0055896 ! PTK7_HUMAN relationship: location_of CCO:B0055898 ! CRFR2_HUMAN relationship: location_of CCO:B0055907 ! ILK_HUMAN relationship: location_of CCO:B0055909 ! TMED1_HUMAN relationship: location_of CCO:B0055912 ! MADCA_HUMAN relationship: location_of CCO:B0055913 ! IL18R_HUMAN relationship: location_of CCO:B0055916 ! VPP3_HUMAN relationship: location_of CCO:B0055932 ! DGKZ_HUMAN relationship: location_of CCO:B0055934 ! OR2F1_HUMAN relationship: location_of CCO:B0055937 ! 5HT4R_HUMAN relationship: location_of CCO:B0055939 ! ITA7_HUMAN relationship: location_of CCO:B0055940 ! AVR2B_HUMAN relationship: location_of CCO:B0055943 ! 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OR1Q1_HUMAN relationship: location_of CCO:B0056079 ! OR4D1_HUMAN relationship: location_of CCO:B0056080 ! OR1C1_HUMAN relationship: location_of CCO:B0056081 ! OR8B8_HUMAN relationship: location_of CCO:B0056082 ! OR7A5_HUMAN relationship: location_of CCO:B0056100 ! LT4R1_HUMAN relationship: location_of CCO:B0056104 ! GPR19_HUMAN relationship: location_of CCO:B0056105 ! NPY5R_HUMAN relationship: location_of CCO:B0056107 ! EFNB3_HUMAN relationship: location_of CCO:B0056108 ! RAB30_HUMAN relationship: location_of CCO:B0056127 ! ENOX2_HUMAN relationship: location_of CCO:B0056132 ! CNGA3_HUMAN relationship: location_of CCO:B0056146 ! GP162_HUMAN relationship: location_of CCO:B0056149 ! LY6E_HUMAN relationship: location_of CCO:B0056153 ! DUFFY_HUMAN relationship: location_of CCO:B0056163 ! STX1A_HUMAN relationship: location_of CCO:B0056176 ! DGKD_HUMAN relationship: location_of CCO:B0056178 ! DDR2_HUMAN relationship: location_of CCO:B0056181 ! Q17R53_HUMAN relationship: location_of CCO:B0056189 ! Q17S10_HUMAN relationship: location_of CCO:B0056199 ! MICB_HUMAN relationship: location_of CCO:B0056200 ! MICA_HUMAN relationship: location_of CCO:B0056211 ! Q2M3M4_HUMAN relationship: location_of CCO:B0056215 ! SPRE3_HUMAN relationship: location_of CCO:B0056219 ! Q2NL85_HUMAN relationship: location_of CCO:B0056221 ! Q2PNZ1_HUMAN relationship: location_of CCO:B0056241 ! OR4FL_HUMAN relationship: location_of CCO:B0056248 ! YK037_HUMAN relationship: location_of CCO:B0056294 ! Q495I2_HUMAN relationship: location_of CCO:B0056308 ! GPR33_HUMAN relationship: location_of CCO:B0056310 ! Q4F7X0_HUMAN relationship: location_of CCO:B0056311 ! Q4G0K7_HUMAN relationship: location_of CCO:B0056320 ! PLCH1_HUMAN relationship: location_of CCO:B0056342 ! Q50KZ9_HUMAN relationship: location_of CCO:B0056345 ! Q52R92_HUMAN relationship: location_of CCO:B0056346 ! Q52R94_HUMAN relationship: location_of CCO:B0056355 ! 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LRRK2_HUMAN relationship: location_of CCO:B0056532 ! Q5SPL1_HUMAN relationship: location_of CCO:B0056538 ! Q5STG5_HUMAN relationship: location_of CCO:B0056540 ! Q5SUJ7_HUMAN relationship: location_of CCO:B0056541 ! Q5SUK1_HUMAN relationship: location_of CCO:B0056543 ! Q5SUN9_HUMAN relationship: location_of CCO:B0056579 ! Q5T4Y8_HUMAN relationship: location_of CCO:B0056585 ! Q5T5Y4_HUMAN relationship: location_of CCO:B0056586 ! GP110_HUMAN relationship: location_of CCO:B0056592 ! GPC6A_HUMAN relationship: location_of CCO:B0056596 ! GP158_HUMAN relationship: location_of CCO:B0056601 ! GP177_HUMAN relationship: location_of CCO:B0056605 ! FRY_HUMAN relationship: location_of CCO:B0056637 ! OR2G6_HUMAN relationship: location_of CCO:B0056640 ! GP157_HUMAN relationship: location_of CCO:B0056641 ! Q5UBV6_HUMAN relationship: location_of CCO:B0056645 ! Q5VT14_HUMAN relationship: location_of CCO:B0056650 ! Q5VTU6_HUMAN relationship: location_of CCO:B0056665 ! Q5VX04_HUMAN relationship: location_of CCO:B0056685 ! CD276_HUMAN relationship: location_of CCO:B0056691 ! Q63ZY2_HUMAN relationship: location_of CCO:B0056694 ! Q658W4_HUMAN relationship: location_of CCO:B0056727 ! MCTP1_HUMAN relationship: location_of CCO:B0056730 ! GP139_HUMAN relationship: location_of CCO:B0056752 ! Q6I939_HUMAN relationship: location_of CCO:B0056753 ! Q6I940_HUMAN relationship: location_of CCO:B0056756 ! SIGIR_HUMAN relationship: location_of CCO:B0056760 ! OR5MA_HUMAN relationship: location_of CCO:B0056762 ! Q6IEV1_HUMAN relationship: location_of CCO:B0056763 ! Q6IEV3_HUMAN relationship: location_of CCO:B0056764 ! OR4CB_HUMAN relationship: location_of CCO:B0056765 ! Q6IEW7_HUMAN relationship: location_of CCO:B0056766 ! Q6IEX0_HUMAN relationship: location_of CCO:B0056767 ! Q6IEX5_HUMAN relationship: location_of CCO:B0056768 ! OR4F3_HUMAN relationship: location_of CCO:B0056769 ! Q6IEZ1_HUMAN relationship: location_of CCO:B0056770 ! Q6IEZ4_HUMAN relationship: location_of CCO:B0056771 ! OR2T5_HUMAN relationship: location_of CCO:B0056772 ! OR2T2_HUMAN relationship: location_of CCO:B0056773 ! Q6IF09_HUMAN relationship: location_of CCO:B0056774 ! Q6IF12_HUMAN relationship: location_of CCO:B0056775 ! Q6IF17_HUMAN relationship: location_of CCO:B0056776 ! Q6IF36_HUMAN relationship: location_of CCO:B0056777 ! Q6IF40_HUMAN relationship: location_of CCO:B0056778 ! OR2A2_HUMAN relationship: location_of CCO:B0056779 ! Q6IF52_HUMAN relationship: location_of CCO:B0056780 ! O52W1_HUMAN relationship: location_of CCO:B0056781 ! Q6IF70_HUMAN relationship: location_of CCO:B0056782 ! Q6IF79_HUMAN relationship: location_of CCO:B0056783 ! O4A47_HUMAN relationship: location_of CCO:B0056784 ! O10K2_HUMAN relationship: location_of CCO:B0056785 ! Q6IFB0_HUMAN relationship: location_of CCO:B0056786 ! Q6IFD1_HUMAN relationship: location_of CCO:B0056787 ! Q6IFD3_HUMAN relationship: location_of CCO:B0056788 ! Q6IFD6_HUMAN relationship: location_of CCO:B0056790 ! Q6IFG3_HUMAN relationship: location_of CCO:B0056791 ! Q6IFG5_HUMAN relationship: location_of CCO:B0056792 ! Q6IFG6_HUMAN relationship: location_of CCO:B0056793 ! Q6IFG8_HUMAN relationship: location_of CCO:B0056794 ! OR6B2_HUMAN relationship: location_of CCO:B0056795 ! Q6IFH9_HUMAN relationship: location_of CCO:B0056796 ! Q6IFI0_HUMAN relationship: location_of CCO:B0056797 ! Q6IFI1_HUMAN relationship: location_of CCO:B0056798 ! Q6IFI5_HUMAN relationship: location_of CCO:B0056799 ! Q6IFI7_HUMAN relationship: location_of CCO:B0056800 ! Q6IFI8_HUMAN relationship: location_of CCO:B0056801 ! Q6IFJ4_HUMAN relationship: location_of CCO:B0056802 ! Q6IFJ8_HUMAN relationship: location_of CCO:B0056803 ! Q6IFK7_HUMAN relationship: location_of CCO:B0056804 ! Q6IFK8_HUMAN relationship: location_of CCO:B0056805 ! Q6IFK9_HUMAN relationship: location_of CCO:B0056806 ! Q6IFL0_HUMAN relationship: location_of CCO:B0056807 ! Q6IFL1_HUMAN relationship: location_of CCO:B0056808 ! Q6IFL9_HUMAN relationship: location_of CCO:B0056809 ! Q6IFM6_HUMAN relationship: location_of CCO:B0056810 ! Q6IFM8_HUMAN relationship: location_of CCO:B0056811 ! Q6IFN2_HUMAN relationship: location_of CCO:B0056812 ! Q6IFN7_HUMAN relationship: location_of CCO:B0056813 ! Q6IFP3_HUMAN relationship: location_of CCO:B0056814 ! Q6IFP9_HUMAN relationship: location_of CCO:B0056815 ! Q6IFR1_HUMAN relationship: location_of CCO:B0056816 ! Q6IFR4_HUMAN relationship: location_of CCO:B0056817 ! Q6IFR5_HUMAN relationship: location_of CCO:B0056818 ! Q6IFS1_HUMAN relationship: location_of CCO:B0056833 ! Q6KAV0_HUMAN relationship: location_of CCO:B0056842 ! R7BP_HUMAN relationship: location_of CCO:B0056843 ! Q6MZT2_HUMAN relationship: location_of CCO:B0056849 ! Q6N0A5_HUMAN relationship: location_of CCO:B0056859 ! Q6NTB5_HUMAN relationship: location_of CCO:B0056860 ! Q6NUP5_HUMAN relationship: location_of CCO:B0056862 ! GP153_HUMAN relationship: location_of CCO:B0056863 ! RGMB_HUMAN relationship: location_of CCO:B0056874 ! BORG3_HUMAN relationship: location_of CCO:B0056885 ! Q6P2H9_HUMAN relationship: location_of CCO:B0056886 ! Q6P2M6_HUMAN relationship: location_of CCO:B0056898 ! CNKR3_HUMAN relationship: location_of CCO:B0056908 ! CNIH2_HUMAN relationship: location_of CCO:B0056916 ! TRAT1_HUMAN relationship: location_of CCO:B0056924 ! ZNT9_HUMAN relationship: location_of CCO:B0056934 ! GP133_HUMAN relationship: location_of CCO:B0056936 ! Q6RKA3_HUMAN relationship: location_of CCO:B0056938 ! SHC4_HUMAN relationship: location_of CCO:B0056939 ! Q6S992_HUMAN relationship: location_of CCO:B0056946 ! OPN5_HUMAN relationship: location_of CCO:B0056951 ! MOXD1_HUMAN relationship: location_of CCO:B0056952 ! I27RA_HUMAN relationship: location_of CCO:B0056953 ! ENPP7_HUMAN relationship: location_of CCO:B0056954 ! Q6UXT6_HUMAN relationship: location_of CCO:B0056955 ! GFRAL_HUMAN relationship: location_of CCO:B0056960 ! KSR2_HUMAN relationship: location_of CCO:B0056968 ! NPSR1_HUMAN relationship: location_of CCO:B0056978 ! Q6ZMK5_HUMAN relationship: location_of CCO:B0056984 ! Q6ZMN0_HUMAN relationship: location_of CCO:B0056986 ! Q6ZMP1_HUMAN relationship: location_of CCO:B0057010 ! UNC5A_HUMAN relationship: location_of CCO:B0057028 ! YP009_HUMAN relationship: location_of CCO:B0057050 ! R9BP_HUMAN relationship: location_of CCO:B0057068 ! Q6ZT94_HUMAN relationship: location_of CCO:B0057077 ! Q6ZUP3_HUMAN relationship: location_of CCO:B0057084 ! Q6ZVJ0_HUMAN relationship: location_of CCO:B0057089 ! Q6ZW62_HUMAN relationship: location_of CCO:B0057092 ! RAPH1_HUMAN relationship: location_of CCO:B0057093 ! CR3L2_HUMAN relationship: location_of CCO:B0057094 ! Q711G2_HUMAN relationship: location_of CCO:B0057095 ! Q712M9_HUMAN relationship: location_of CCO:B0057099 ! Q71U75_HUMAN relationship: location_of CCO:B0057100 ! Q71V81_HUMAN relationship: location_of CCO:B0057113 ! RHOU_HUMAN relationship: location_of CCO:B0057125 ! T2R42_HUMAN relationship: location_of CCO:B0057139 ! TS1R3_HUMAN relationship: location_of CCO:B0057140 ! TS1R1_HUMAN relationship: location_of CCO:B0057154 ! OR2W3_HUMAN relationship: location_of CCO:B0057159 ! PK1L2_HUMAN relationship: location_of CCO:B0057160 ! PK1L3_HUMAN relationship: location_of CCO:B0057161 ! RASE_HUMAN relationship: location_of CCO:B0057181 ! VN1R5_HUMAN relationship: location_of CCO:B0057182 ! VN1R4_HUMAN relationship: location_of CCO:B0057188 ! GP142_HUMAN relationship: location_of CCO:B0057189 ! GP141_HUMAN relationship: location_of CCO:B0057194 ! SPRE2_HUMAN relationship: location_of CCO:B0057195 ! SPRE1_HUMAN relationship: location_of CCO:B0057199 ! RAB44_HUMAN relationship: location_of CCO:B0057208 ! Q7Z783_HUMAN relationship: location_of CCO:B0057220 ! GP144_HUMAN relationship: location_of CCO:B0057221 ! Q86SE3_HUMAN relationship: location_of CCO:B0057223 ! Q86SF1_HUMAN relationship: location_of CCO:B0057224 ! Q86SF3_HUMAN relationship: location_of CCO:B0057225 ! Q86SG0_HUMAN relationship: location_of CCO:B0057226 ! Q86SG9_HUMAN relationship: location_of CCO:B0057227 ! Q86SI5_HUMAN relationship: location_of CCO:B0057228 ! AMGO2_HUMAN relationship: location_of CCO:B0057229 ! MRGRG_HUMAN relationship: location_of CCO:B0057231 ! GP149_HUMAN relationship: location_of CCO:B0057232 ! EMR4_HUMAN relationship: location_of CCO:B0057233 ! GP123_HUMAN relationship: location_of CCO:B0057242 ! Q86TY6_HUMAN relationship: location_of CCO:B0057254 ! NOXA1_HUMAN relationship: location_of CCO:B0057270 ! Q86W07_HUMAN relationship: location_of CCO:B0057273 ! KCMB4_HUMAN relationship: location_of CCO:B0057275 ! AMGO1_HUMAN relationship: location_of CCO:B0057288 ! Q86XI1_HUMAN relationship: location_of CCO:B0057293 ! TCAM2_HUMAN relationship: location_of CCO:B0057300 ! GPR97_HUMAN relationship: location_of CCO:B0057306 ! PDPN_HUMAN relationship: location_of CCO:B0057307 ! HOME1_HUMAN relationship: location_of CCO:B0057312 ! MIB1_HUMAN relationship: location_of CCO:B0057316 ! Q86YZ7_HUMAN relationship: location_of CCO:B0057318 ! I28RA_HUMAN relationship: location_of CCO:B0057323 ! ZDH13_HUMAN relationship: location_of CCO:B0057324 ! ZDH17_HUMAN relationship: location_of CCO:B0057333 ! Q8IV15_HUMAN relationship: location_of CCO:B0057335 ! UN5CL_HUMAN relationship: location_of CCO:B0057354 ! Q8IW90_HUMAN relationship: location_of CCO:B0057356 ! CTL2_HUMAN relationship: location_of CCO:B0057365 ! CNTN4_HUMAN relationship: location_of CCO:B0057369 ! SACA3_HUMAN relationship: location_of CCO:B0057370 ! Q8IXD9_HUMAN relationship: location_of CCO:B0057371 ! Q8IXE0_HUMAN relationship: location_of CCO:B0057372 ! OR4N5_HUMAN relationship: location_of CCO:B0057373 ! Q8IXE4_HUMAN relationship: location_of CCO:B0057377 ! MIRO2_HUMAN relationship: location_of CCO:B0057378 ! MIRO1_HUMAN relationship: location_of CCO:B0057389 ! REM2_HUMAN relationship: location_of CCO:B0057402 ! GP116_HUMAN relationship: location_of CCO:B0057403 ! GP115_HUMAN relationship: location_of CCO:B0057404 ! GP114_HUMAN relationship: location_of CCO:B0057405 ! GP113_HUMAN relationship: location_of CCO:B0057406 ! GP111_HUMAN relationship: location_of CCO:B0057407 ! UNC5B_HUMAN relationship: location_of CCO:B0057413 ! Q8N0W0_HUMAN relationship: location_of CCO:B0057414 ! Q8N0W1_HUMAN relationship: location_of CCO:B0057415 ! Q8N0X1_HUMAN relationship: location_of CCO:B0057417 ! OR4N4_HUMAN relationship: location_of CCO:B0057418 ! OR8I2_HUMAN relationship: location_of CCO:B0057421 ! SHSA5_HUMAN relationship: location_of CCO:B0057423 ! LIRA2_HUMAN relationship: location_of CCO:B0057424 ! Q8N164_HUMAN relationship: location_of CCO:B0057431 ! CRPAK_HUMAN relationship: location_of CCO:B0057433 ! RGNEF_HUMAN relationship: location_of CCO:B0057443 ! ARM10_HUMAN relationship: location_of CCO:B0057446 ! NLGN1_HUMAN relationship: location_of CCO:B0057453 ! OR2LD_HUMAN relationship: location_of CCO:B0057459 ! LIRB2_HUMAN relationship: location_of CCO:B0057462 ! FGRL1_HUMAN relationship: location_of CCO:B0057479 ! M4A15_HUMAN relationship: location_of CCO:B0057483 ! OR2C3_HUMAN relationship: location_of CCO:B0057486 ! IGSF1_HUMAN relationship: location_of CCO:B0057494 ! GP161_HUMAN relationship: location_of CCO:B0057556 ! UN13C_HUMAN relationship: location_of CCO:B0057560 ! CLC1A_HUMAN relationship: location_of CCO:B0057570 ! KCNH5_HUMAN relationship: location_of CCO:B0057574 ! KREM2_HUMAN relationship: location_of CCO:B0057581 ! GPR26_HUMAN relationship: location_of CCO:B0057584 ! PSD4_HUMAN relationship: location_of CCO:B0057598 ! NOXO1_HUMAN relationship: location_of CCO:B0057604 ! PKR2_HUMAN relationship: location_of CCO:B0057606 ! 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OR7A2_HUMAN relationship: location_of CCO:B0057632 ! Q8NGA3_HUMAN relationship: location_of CCO:B0057634 ! O10H4_HUMAN relationship: location_of CCO:B0057635 ! O10H5_HUMAN relationship: location_of CCO:B0057636 ! O4F17_HUMAN relationship: location_of CCO:B0057637 ! Q8NGA9_HUMAN relationship: location_of CCO:B0057639 ! OR4C5_HUMAN relationship: location_of CCO:B0057640 ! OR4S1_HUMAN relationship: location_of CCO:B0057641 ! Q8NGB5_HUMAN relationship: location_of CCO:B0057642 ! OR4M2_HUMAN relationship: location_of CCO:B0057643 ! O4F15_HUMAN relationship: location_of CCO:B0057644 ! OR4F6_HUMAN relationship: location_of CCO:B0057645 ! OR4E2_HUMAN relationship: location_of CCO:B0057646 ! O10G2_HUMAN relationship: location_of CCO:B0057647 ! O10G3_HUMAN relationship: location_of CCO:B0057648 ! OR6J1_HUMAN relationship: location_of CCO:B0057649 ! O11H6_HUMAN relationship: location_of CCO:B0057650 ! O11H7_HUMAN relationship: location_of CCO:B0057651 ! O11H4_HUMAN relationship: location_of CCO:B0057652 ! OR4M1_HUMAN relationship: location_of CCO:B0057653 ! OR4N2_HUMAN relationship: location_of CCO:B0057654 ! OR4K2_HUMAN relationship: location_of CCO:B0057655 ! OR4K5_HUMAN relationship: location_of CCO:B0057656 ! OR4K1_HUMAN relationship: location_of CCO:B0057657 ! OR4KE_HUMAN relationship: location_of CCO:B0057658 ! O10AD_HUMAN relationship: location_of CCO:B0057659 ! OR6C4_HUMAN relationship: location_of CCO:B0057660 ! O2AP1_HUMAN relationship: location_of CCO:B0057661 ! O10A7_HUMAN relationship: location_of CCO:B0057662 ! Q8NGE6_HUMAN relationship: location_of CCO:B0057663 ! OR4D9_HUMAN relationship: location_of CCO:B0057664 ! Q8NGF2_HUMAN relationship: location_of CCO:B0057665 ! O51D1_HUMAN relationship: location_of CCO:B0057666 ! O10W1_HUMAN relationship: location_of CCO:B0057667 ! OR4B1_HUMAN relationship: location_of CCO:B0057668 ! OR4X2_HUMAN relationship: location_of CCO:B0057669 ! OR8J3_HUMAN relationship: location_of CCO:B0057670 ! OR8J2_HUMAN relationship: location_of CCO:B0057671 ! OR8K1_HUMAN relationship: location_of CCO:B0057672 ! OR8BC_HUMAN relationship: location_of CCO:B0057673 ! OR8B3_HUMAN relationship: location_of CCO:B0057674 ! Q8NGG9_HUMAN relationship: location_of CCO:B0057675 ! Q8NGH2_HUMAN relationship: location_of CCO:B0057676 ! O52E4_HUMAN relationship: location_of CCO:B0057677 ! O52N2_HUMAN relationship: location_of CCO:B0057678 ! O56B2_HUMAN relationship: location_of CCO:B0057679 ! O52N4_HUMAN relationship: location_of CCO:B0057680 ! O56B1_HUMAN relationship: location_of CCO:B0057681 ! OR4DB_HUMAN relationship: location_of CCO:B0057682 ! Q8NGI5_HUMAN relationship: location_of CCO:B0057683 ! OR4DA_HUMAN relationship: location_of CCO:B0057684 ! O10V1_HUMAN relationship: location_of CCO:B0057685 ! O5AN1_HUMAN relationship: location_of CCO:B0057686 ! OR5A2_HUMAN relationship: location_of CCO:B0057687 ! OR5A1_HUMAN relationship: location_of CCO:B0057688 ! OR4D6_HUMAN relationship: location_of CCO:B0057689 ! O52E1_HUMAN relationship: location_of CCO:B0057690 ! O52E2_HUMAN relationship: location_of CCO:B0057691 ! O51L1_HUMAN relationship: location_of CCO:B0057692 ! O51A4_HUMAN relationship: location_of CCO:B0057693 ! O51A2_HUMAN relationship: location_of CCO:B0057694 ! O51S1_HUMAN relationship: location_of CCO:B0057695 ! O51G2_HUMAN relationship: location_of CCO:B0057696 ! O51G1_HUMAN relationship: location_of CCO:B0057697 ! O52B4_HUMAN relationship: location_of CCO:B0057698 ! O52K2_HUMAN relationship: location_of CCO:B0057699 ! O52K1_HUMAN relationship: location_of CCO:B0057700 ! O52M1_HUMAN relationship: location_of CCO:B0057701 ! O52I1_HUMAN relationship: location_of CCO:B0057702 ! Q8NGK8_HUMAN relationship: location_of CCO:B0057703 ! OR5DG_HUMAN relationship: location_of CCO:B0057704 ! OR5DI_HUMAN relationship: location_of CCO:B0057705 ! OR5DE_HUMAN relationship: location_of CCO:B0057706 ! OR5DD_HUMAN relationship: location_of CCO:B0057707 ! Q8NGL5_HUMAN relationship: location_of CCO:B0057708 ! O4A15_HUMAN relationship: location_of CCO:B0057709 ! OR4P4_HUMAN relationship: location_of CCO:B0057710 ! OR4CG_HUMAN relationship: location_of CCO:B0057711 ! Q8NGM0_HUMAN relationship: location_of CCO:B0057712 ! OR4CF_HUMAN relationship: location_of CCO:B0057713 ! Q8NGM3_HUMAN relationship: location_of CCO:B0057714 ! Q8NGM4_HUMAN relationship: location_of CCO:B0057716 ! Q8NGM6_HUMAN relationship: location_of CCO:B0057717 ! Q8NGM7_HUMAN relationship: location_of CCO:B0057718 ! OR4D5_HUMAN relationship: location_of CCO:B0057719 ! OR6T1_HUMAN relationship: location_of CCO:B0057720 ! O10G4_HUMAN relationship: location_of CCO:B0057721 ! O10G9_HUMAN relationship: location_of CCO:B0057722 ! O10G8_HUMAN relationship: location_of CCO:B0057723 ! O10G7_HUMAN relationship: location_of CCO:B0057724 ! O10D4_HUMAN relationship: location_of CCO:B0057725 ! OR4A4_HUMAN relationship: location_of CCO:B0057726 ! Q8NGN9_HUMAN relationship: location_of CCO:B0057727 ! OR4CD_HUMAN relationship: location_of CCO:B0057728 ! OR8J1_HUMAN relationship: location_of CCO:B0057729 ! OR5M9_HUMAN relationship: location_of CCO:B0057730 ! OR5M3_HUMAN relationship: location_of CCO:B0057731 ! Q8NGP5_HUMAN relationship: location_of CCO:B0057732 ! OR5M8_HUMAN relationship: location_of CCO:B0057734 ! OR5M1_HUMAN relationship: location_of CCO:B0057735 ! OR6Q1_HUMAN relationship: location_of CCO:B0057736 ! O10Q1_HUMAN relationship: location_of CCO:B0057737 ! OR9Q1_HUMAN relationship: location_of CCO:B0057738 ! Q8NGQ7_HUMAN relationship: location_of CCO:B0057739 ! OR1K1_HUMAN relationship: location_of CCO:B0057740 ! OR1L4_HUMAN relationship: location_of CCO:B0057741 ! OR1B1_HUMAN relationship: location_of CCO:B0057742 ! OR1L8_HUMAN relationship: location_of CCO:B0057743 ! OR1N1_HUMAN relationship: location_of CCO:B0057744 ! OR1J4_HUMAN relationship: location_of CCO:B0057745 ! OR1J2_HUMAN relationship: location_of CCO:B0057746 ! OR1J1_HUMAN relationship: location_of CCO:B0057747 ! O13F1_HUMAN relationship: location_of CCO:B0057748 ! O13C4_HUMAN relationship: location_of CCO:B0057749 ! O13C8_HUMAN relationship: location_of CCO:B0057750 ! O13C5_HUMAN relationship: location_of CCO:B0057751 ! O13C2_HUMAN relationship: location_of CCO:B0057752 ! O13C9_HUMAN relationship: location_of CCO:B0057753 ! OR2K1_HUMAN relationship: location_of CCO:B0057754 ! O13J1_HUMAN relationship: location_of CCO:B0057755 ! OR9A2_HUMAN relationship: location_of CCO:B0057756 ! O2A12_HUMAN relationship: location_of CCO:B0057757 ! OR2A1_HUMAN relationship: location_of CCO:B0057758 ! Q8NGU0_HUMAN relationship: location_of CCO:B0057759 ! OR9A1_HUMAN relationship: location_of CCO:B0057760 ! OR9A4_HUMAN relationship: location_of CCO:B0057762 ! OR2I1_HUMAN relationship: location_of CCO:B0057764 ! Q8NGU7_HUMAN relationship: location_of CCO:B0057765 ! GP150_HUMAN relationship: location_of CCO:B0057766 ! OR2Y1_HUMAN relationship: location_of CCO:B0057768 ! CSRL1_HUMAN relationship: location_of CCO:B0057769 ! OR6B3_HUMAN relationship: location_of CCO:B0057771 ! Q8NGW3_HUMAN relationship: location_of CCO:B0057772 ! O11L1_HUMAN relationship: location_of CCO:B0057773 ! O2T34_HUMAN relationship: location_of CCO:B0057774 ! O2T35_HUMAN relationship: location_of CCO:B0057775 ! O10T2_HUMAN relationship: location_of CCO:B0057776 ! Q8NGX4_HUMAN relationship: location_of CCO:B0057777 ! O10K1_HUMAN relationship: location_of CCO:B0057778 ! Q8NGX7_HUMAN relationship: location_of CCO:B0057779 ! OR6Y1_HUMAN relationship: location_of CCO:B0057780 ! OR6P1_HUMAN relationship: location_of CCO:B0057781 ! O10X1_HUMAN relationship: location_of CCO:B0057782 ! O10Z1_HUMAN relationship: location_of CCO:B0057783 ! OR6K2_HUMAN relationship: location_of CCO:B0057784 ! Q8NGY4_HUMAN relationship: location_of CCO:B0057785 ! OR6N1_HUMAN relationship: location_of CCO:B0057786 ! OR6N2_HUMAN relationship: location_of CCO:B0057787 ! O10J6_HUMAN relationship: location_of CCO:B0057788 ! OR2L8_HUMAN relationship: location_of CCO:B0057789 ! O2AJ1_HUMAN relationship: location_of CCO:B0057790 ! O14K1_HUMAN relationship: location_of CCO:B0057791 ! O13G1_HUMAN relationship: location_of CCO:B0057792 ! OR2G3_HUMAN relationship: location_of CCO:B0057793 ! OR2G2_HUMAN relationship: location_of CCO:B0057794 ! OR6F1_HUMAN relationship: location_of CCO:B0057795 ! O2T10_HUMAN relationship: location_of CCO:B0057796 ! OR2T4_HUMAN relationship: location_of CCO:B0057797 ! O2T11_HUMAN relationship: location_of CCO:B0057798 ! O2T29_HUMAN relationship: location_of CCO:B0057799 ! OR2T3_HUMAN relationship: location_of CCO:B0057800 ! O2T27_HUMAN relationship: location_of CCO:B0057801 ! OR4Q3_HUMAN relationship: location_of CCO:B0057802 ! OR1P1_HUMAN relationship: location_of CCO:B0057803 ! O11H2_HUMAN relationship: location_of CCO:B0057804 ! O10AC_HUMAN relationship: location_of CCO:B0057805 ! OR8S1_HUMAN relationship: location_of CCO:B0057806 ! Q8NH11_HUMAN relationship: location_of CCO:B0057807 ! Q8NH14_HUMAN relationship: location_of CCO:B0057808 ! OR2L2_HUMAN relationship: location_of CCO:B0057809 ! Q8NH17_HUMAN relationship: location_of CCO:B0057810 ! O10AG_HUMAN relationship: location_of CCO:B0057811 ! OR4F5_HUMAN relationship: location_of CCO:B0057814 ! Q8NH24_HUMAN relationship: location_of CCO:B0057815 ! Q8NH27_HUMAN relationship: location_of CCO:B0057816 ! Q8NH29_HUMAN relationship: location_of CCO:B0057817 ! Q8NH32_HUMAN relationship: location_of CCO:B0057818 ! Q8NH33_HUMAN relationship: location_of CCO:B0057819 ! Q8NH36_HUMAN relationship: location_of CCO:B0057820 ! OR4C3_HUMAN relationship: location_of CCO:B0057821 ! Q8NH38_HUMAN relationship: location_of CCO:B0057822 ! OR4KD_HUMAN relationship: location_of CCO:B0057823 ! OR4L1_HUMAN relationship: location_of CCO:B0057824 ! Q8NH44_HUMAN relationship: location_of CCO:B0057825 ! Q8NH47_HUMAN relationship: location_of CCO:B0057826 ! OR4X1_HUMAN relationship: location_of CCO:B0057827 ! OR8K3_HUMAN relationship: location_of CCO:B0057828 ! O52N1_HUMAN relationship: location_of CCO:B0057830 ! O52E5_HUMAN relationship: location_of CCO:B0057831 ! O52N5_HUMAN relationship: location_of CCO:B0057832 ! O52P1_HUMAN relationship: location_of CCO:B0057833 ! Q8NH58_HUMAN relationship: location_of CCO:B0057834 ! O51Q1_HUMAN relationship: location_of CCO:B0057835 ! O52J3_HUMAN relationship: location_of CCO:B0057836 ! Q8NH62_HUMAN relationship: location_of CCO:B0057837 ! O51H1_HUMAN relationship: location_of CCO:B0057838 ! O51A7_HUMAN relationship: location_of CCO:B0057839 ! Q8NH66_HUMAN relationship: location_of CCO:B0057840 ! Q8NH68_HUMAN relationship: location_of CCO:B0057841 ! O4A16_HUMAN relationship: location_of CCO:B0057842 ! Q8NH71_HUMAN relationship: location_of CCO:B0057843 ! OR4C6_HUMAN relationship: location_of CCO:B0057845 ! O10A6_HUMAN relationship: location_of CCO:B0057846 ! Q8NH75_HUMAN relationship: location_of CCO:B0057847 ! O56B4_HUMAN relationship: location_of CCO:B0057848 ! Q8NH77_HUMAN relationship: location_of CCO:B0057849 ! Q8NH78_HUMAN relationship: location_of CCO:B0057850 ! OR6X1_HUMAN relationship: location_of CCO:B0057851 ! O10D3_HUMAN relationship: location_of CCO:B0057852 ! O10G6_HUMAN relationship: location_of CCO:B0057853 ! Q8NH82_HUMAN relationship: location_of CCO:B0057854 ! OR4A5_HUMAN relationship: location_of CCO:B0057855 ! Q8NH84_HUMAN relationship: location_of CCO:B0057856 ! Q8NH86_HUMAN relationship: location_of CCO:B0057857 ! OR9G1_HUMAN relationship: location_of CCO:B0057858 ! Q8NH88_HUMAN relationship: location_of CCO:B0057859 ! 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CNIH3_HUMAN relationship: location_of CCO:B0057913 ! O51E1_HUMAN relationship: location_of CCO:B0057916 ! CERK1_HUMAN relationship: location_of CCO:B0057917 ! PKR1_HUMAN relationship: location_of CCO:B0057919 ! PKHD1_HUMAN relationship: location_of CCO:B0057927 ! GRP4_HUMAN relationship: location_of CCO:B0057929 ! Q8TDP6_HUMAN relationship: location_of CCO:B0057930 ! Q8TDP8_HUMAN relationship: location_of CCO:B0057932 ! G109A_HUMAN relationship: location_of CCO:B0057933 ! OXER1_HUMAN relationship: location_of CCO:B0057934 ! MRGRD_HUMAN relationship: location_of CCO:B0057935 ! GP152_HUMAN relationship: location_of CCO:B0057936 ! Q8TDT4_HUMAN relationship: location_of CCO:B0057937 ! Q8TDT9_HUMAN relationship: location_of CCO:B0057938 ! VNRL4_HUMAN relationship: location_of CCO:B0057939 ! GPBAR_HUMAN relationship: location_of CCO:B0057940 ! RL3R2_HUMAN relationship: location_of CCO:B0057941 ! GP151_HUMAN relationship: location_of CCO:B0057943 ! 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FXYD5_HUMAN relationship: location_of CCO:B0058196 ! M4A6E_HUMAN relationship: location_of CCO:B0058200 ! RAB3C_HUMAN relationship: location_of CCO:B0058202 ! KLRG1_HUMAN relationship: location_of CCO:B0058213 ! P2Y11_HUMAN relationship: location_of CCO:B0058222 ! MS4A3_HUMAN relationship: location_of CCO:B0058229 ! TM101_HUMAN relationship: location_of CCO:B0058236 ! M4A14_HUMAN relationship: location_of CCO:B0058248 ! M4A4A_HUMAN relationship: location_of CCO:B0058255 ! GP128_HUMAN relationship: location_of CCO:B0058259 ! O10C1_HUMAN relationship: location_of CCO:B0058264 ! RHOV_HUMAN relationship: location_of CCO:B0058265 ! KCNH8_HUMAN relationship: location_of CCO:B0058268 ! MRGX4_HUMAN relationship: location_of CCO:B0058269 ! MRGX3_HUMAN relationship: location_of CCO:B0058270 ! MRGX2_HUMAN relationship: location_of CCO:B0058271 ! MRGX1_HUMAN relationship: location_of CCO:B0058281 ! Q96M80_HUMAN relationship: location_of CCO:B0058294 ! KREM1_HUMAN relationship: location_of CCO:B0058305 ! CF170_HUMAN relationship: location_of CCO:B0058313 ! CNT3B_HUMAN relationship: location_of CCO:B0058320 ! QRFPR_HUMAN relationship: location_of CCO:B0058321 ! GP101_HUMAN relationship: location_of CCO:B0058322 ! GPR82_HUMAN relationship: location_of CCO:B0058323 ! OXGR1_HUMAN relationship: location_of CCO:B0058324 ! GPR78_HUMAN relationship: location_of CCO:B0058326 ! GNRR2_HUMAN relationship: location_of CCO:B0058328 ! DCBD2_HUMAN relationship: location_of CCO:B0058329 ! GP124_HUMAN relationship: location_of CCO:B0058333 ! M4A4E_HUMAN relationship: location_of CCO:B0058334 ! M4A10_HUMAN relationship: location_of CCO:B0058335 ! NOX5_HUMAN relationship: location_of CCO:B0058351 ! DERL3_HUMAN relationship: location_of CCO:B0058358 ! MAGI1_HUMAN relationship: location_of CCO:B0058359 ! OR2M4_HUMAN relationship: location_of CCO:B0058360 ! OR2M2_HUMAN relationship: location_of CCO:B0058361 ! OR2V2_HUMAN relationship: location_of CCO:B0058362 ! OR2A7_HUMAN relationship: location_of CCO:B0058363 ! O2A14_HUMAN relationship: location_of CCO:B0058364 ! OR2A5_HUMAN relationship: location_of CCO:B0058365 ! O14A2_HUMAN relationship: location_of CCO:B0058366 ! OR4CC_HUMAN relationship: location_of CCO:B0058367 ! OR4F4_HUMAN relationship: location_of CCO:B0058368 ! OR4K3_HUMAN relationship: location_of CCO:B0058369 ! OR1F2_HUMAN relationship: location_of CCO:B0058370 ! OR7D2_HUMAN relationship: location_of CCO:B0058371 ! OR8B2_HUMAN relationship: location_of CCO:B0058372 ! OR6C1_HUMAN relationship: location_of CCO:B0058373 ! O52E6_HUMAN relationship: location_of CCO:B0058377 ! TAAR6_HUMAN relationship: location_of CCO:B0058378 ! TAAR9_HUMAN relationship: location_of CCO:B0058379 ! TAAR1_HUMAN relationship: location_of CCO:B0058384 ! RB40C_HUMAN relationship: location_of CCO:B0058401 ! PP16B_HUMAN relationship: location_of CCO:B0058407 ! CSF3R_HUMAN relationship: location_of CCO:B0058410 ! CYH2_HUMAN relationship: location_of CCO:B0058414 ! NOTC4_HUMAN relationship: location_of CCO:B0058418 ! S1PR3_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058422 ! GPER_HUMAN relationship: location_of CCO:B0058423 ! P2RX4_HUMAN relationship: location_of CCO:B0058426 ! RIT2_HUMAN relationship: location_of CCO:B0058436 ! Q99662_HUMAN relationship: location_of CCO:B0058438 ! GPR20_HUMAN relationship: location_of CCO:B0058439 ! GPR21_HUMAN relationship: location_of CCO:B0058440 ! GPR22_HUMAN relationship: location_of CCO:B0058444 ! MCHR1_HUMAN relationship: location_of CCO:B0058445 ! KI2L4_HUMAN relationship: location_of CCO:B0058449 ! LITAF_HUMAN relationship: location_of CCO:B0058450 ! MGST2_HUMAN relationship: location_of CCO:B0058454 ! CML1_HUMAN relationship: location_of CCO:B0058463 ! ATF6B_HUMAN relationship: location_of CCO:B0058465 ! SEM3C_HUMAN relationship: location_of CCO:B0058469 ! P2Y13_HUMAN relationship: location_of CCO:B0058480 ! SELS_HUMAN relationship: location_of CCO:B0058482 ! PSD2_HUMAN relationship: location_of CCO:B0058489 ! PLCD4_HUMAN relationship: location_of CCO:B0058494 ! AIFM2_HUMAN relationship: location_of CCO:B0058512 ! NFIP1_HUMAN relationship: location_of CCO:B0058548 ! LGR4_HUMAN relationship: location_of CCO:B0058549 ! GPR81_HUMAN relationship: location_of CCO:B0058550 ! GP174_HUMAN relationship: location_of CCO:B0058551 ! VN1R3_HUMAN relationship: location_of CCO:B0058561 ! CLC7A_HUMAN relationship: location_of CCO:B0058562 ! PAPP2_HUMAN relationship: location_of CCO:B0058565 ! EMR3_HUMAN relationship: location_of CCO:B0058566 ! M4A8B_HUMAN relationship: location_of CCO:B0058567 ! GPR87_HUMAN relationship: location_of CCO:B0058577 ! PCD24_HUMAN relationship: location_of CCO:B0058578 ! ACE2_HUMAN relationship: location_of CCO:B0058589 ! Q9BZ69_HUMAN relationship: location_of CCO:B0058590 ! CNTP3_HUMAN relationship: location_of CCO:B0058600 ! GPR63_HUMAN relationship: location_of CCO:B0058601 ! GPR62_HUMAN relationship: location_of CCO:B0058602 ! GPR61_HUMAN relationship: location_of CCO:B0058605 ! B2L14_HUMAN relationship: location_of CCO:B0058624 ! OR2B2_HUMAN relationship: location_of CCO:B0058625 ! OR2H1_HUMAN relationship: location_of CCO:B0058626 ! OR2J1_HUMAN relationship: location_of CCO:B0058627 ! O11A1_HUMAN relationship: location_of CCO:B0058629 ! GPR88_HUMAN relationship: location_of CCO:B0058630 ! VN1R1_HUMAN relationship: location_of CCO:B0058631 ! DERL2_HUMAN relationship: location_of CCO:B0058632 ! NMUR2_HUMAN relationship: location_of CCO:B0058633 ! NPFF1_HUMAN relationship: location_of CCO:B0058646 ! ACH10_HUMAN relationship: location_of CCO:B0058652 ! ARL6_HUMAN relationship: location_of CCO:B0058657 ! RAB17_HUMAN relationship: location_of CCO:B0058663 ! LPAR5_HUMAN relationship: location_of CCO:B0058667 ! OPN3_HUMAN relationship: location_of CCO:B0058668 ! O2AG1_HUMAN relationship: location_of CCO:B0058669 ! O10A5_HUMAN relationship: location_of CCO:B0058670 ! O10A2_HUMAN relationship: location_of CCO:B0058671 ! O10A4_HUMAN relationship: location_of CCO:B0058672 ! OR2D2_HUMAN relationship: location_of CCO:B0058673 ! S1PR5_HUMAN relationship: location_of CCO:B0058674 ! PORCN_HUMAN relationship: location_of CCO:B0058675 ! P2Y12_HUMAN relationship: location_of CCO:B0058676 ! KCNH6_HUMAN relationship: location_of CCO:B0058678 ! O51E2_HUMAN relationship: location_of CCO:B0058681 ! O52A5_HUMAN relationship: location_of CCO:B0058682 ! Q9H2C6_HUMAN relationship: location_of CCO:B0058683 ! O51V1_HUMAN relationship: location_of CCO:B0058685 ! SEM6A_HUMAN relationship: location_of CCO:B0058689 ! M4A6A_HUMAN relationship: location_of CCO:B0058691 ! CLC4M_HUMAN relationship: location_of CCO:B0058694 ! O51B5_HUMAN relationship: location_of CCO:B0058695 ! O51B6_HUMAN relationship: location_of CCO:B0058696 ! O51M1_HUMAN relationship: location_of CCO:B0058697 ! O51J1_HUMAN relationship: location_of CCO:B0058698 ! O51I1_HUMAN relationship: location_of CCO:B0058699 ! O51I2_HUMAN relationship: location_of CCO:B0058700 ! Q9H345_HUMAN relationship: location_of CCO:B0058701 ! O52D1_HUMAN relationship: location_of CCO:B0058705 ! TXND1_HUMAN relationship: location_of CCO:B0058706 ! HRH4_HUMAN relationship: location_of CCO:B0058711 ! MS4A5_HUMAN relationship: location_of CCO:B0058712 ! OFUT1_HUMAN relationship: location_of CCO:B0058743 ! Q9H7Q2_HUMAN relationship: location_of CCO:B0058770 ! TNR27_HUMAN relationship: location_of CCO:B0058773 ! ILRL2_HUMAN relationship: location_of CCO:B0058775 ! Q9HB42_HUMAN relationship: location_of CCO:B0058776 ! Q9HB44_HUMAN relationship: location_of CCO:B0058780 ! NMUR1_HUMAN relationship: location_of CCO:B0058784 ! RHOF_HUMAN relationship: location_of CCO:B0058793 ! ELTD1_HUMAN relationship: location_of CCO:B0058808 ! NGL1_HUMAN relationship: location_of CCO:B0058810 ! ROBO2_HUMAN relationship: location_of CCO:B0058812 ! PLXA4_HUMAN relationship: location_of CCO:B0058814 ! GPVI_HUMAN relationship: location_of CCO:B0058815 ! HHATL_HUMAN relationship: location_of CCO:B0058819 ! PREB_HUMAN relationship: location_of CCO:B0058824 ! Q9HD50_HUMAN relationship: location_of CCO:B0058829 ! CD209_HUMAN relationship: location_of CCO:B0058832 ! IRPL2_HUMAN relationship: location_of CCO:B0058838 ! TNR12_HUMAN relationship: location_of CCO:B0058841 ! RAB9B_HUMAN relationship: location_of CCO:B0058842 ! TREM1_HUMAN relationship: location_of CCO:B0058846 ! LT4R2_HUMAN relationship: location_of CCO:B0058849 ! CD320_HUMAN relationship: location_of CCO:B0058850 ! CENA2_HUMAN relationship: location_of CCO:B0058851 ! FZD3_HUMAN relationship: location_of CCO:B0058853 ! IL1AP_HUMAN relationship: location_of CCO:B0058854 ! NOX4_HUMAN relationship: location_of CCO:B0058858 ! SLAF7_HUMAN relationship: location_of CCO:B0058861 ! TMM9B_HUMAN relationship: location_of CCO:B0058869 ! OR2S1_HUMAN relationship: location_of CCO:B0058872 ! GPR84_HUMAN relationship: location_of CCO:B0058877 ! CNGB3_HUMAN relationship: location_of CCO:B0058888 ! ASAH2_HUMAN relationship: location_of CCO:B0058891 ! TLR9_HUMAN relationship: location_of CCO:B0058892 ! TLR8_HUMAN relationship: location_of CCO:B0058894 ! SPTN5_HUMAN relationship: location_of CCO:B0058896 ! DUOX2_HUMAN relationship: location_of CCO:B0058897 ! DUOX1_HUMAN relationship: location_of CCO:B0058899 ! SH2B1_HUMAN relationship: location_of CCO:B0058903 ! C42S2_HUMAN relationship: location_of CCO:B0058904 ! C42S1_HUMAN relationship: location_of CCO:B0058909 ! GP173_HUMAN relationship: location_of CCO:B0058910 ! GPR27_HUMAN relationship: location_of CCO:B0058911 ! TNR19_HUMAN relationship: location_of CCO:B0058913 ! HOME2_HUMAN relationship: location_of CCO:B0058916 ! Q9NSC9_HUMAN relationship: location_of CCO:B0058918 ! RL3R1_HUMAN relationship: location_of CCO:B0058922 ! Q9NSM3_HUMAN relationship: location_of CCO:B0058925 ! AT8A2_HUMAN relationship: location_of CCO:B0058930 ! NFIP2_HUMAN relationship: location_of CCO:B0058948 ! RHBL2_HUMAN relationship: location_of CCO:B0058952 ! CNTLN_HUMAN relationship: location_of CCO:B0058954 ! M4A12_HUMAN relationship: location_of CCO:B0058957 ! CLC5A_HUMAN relationship: location_of CCO:B0058965 ! GPR83_HUMAN relationship: location_of CCO:B0058975 ! T2R16_HUMAN relationship: location_of CCO:B0058976 ! T2R14_HUMAN relationship: location_of CCO:B0058977 ! T2R13_HUMAN relationship: location_of CCO:B0058978 ! T2R10_HUMAN relationship: location_of CCO:B0058979 ! TA2R9_HUMAN relationship: location_of CCO:B0058980 ! TA2R8_HUMAN relationship: location_of CCO:B0058981 ! TA2R7_HUMAN relationship: location_of CCO:B0058982 ! TA2R4_HUMAN relationship: location_of CCO:B0058983 ! TA2R3_HUMAN relationship: location_of CCO:B0058984 ! TA2R1_HUMAN relationship: location_of CCO:B0058988 ! SIGL8_HUMAN relationship: location_of CCO:B0058989 ! PEN2_HUMAN relationship: location_of CCO:B0058993 ! GPC5D_HUMAN relationship: location_of CCO:B0058995 ! SPG21_HUMAN relationship: location_of CCO:B0058996 ! GPC5B_HUMAN relationship: location_of CCO:B0058998 ! TF2L1_HUMAN relationship: location_of CCO:B0059001 ! MTCH1_HUMAN relationship: location_of CCO:B0059005 ! IRPL1_HUMAN relationship: location_of CCO:B0059007 ! OR6C3_HUMAN relationship: location_of CCO:B0059008 ! OR6C2_HUMAN relationship: location_of CCO:B0059011 ! PD1L1_HUMAN relationship: location_of CCO:B0059014 ! KLRF1_HUMAN relationship: location_of CCO:B0059015 ! BFAR_HUMAN relationship: location_of CCO:B0059024 ! CNIH4_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0059029 ! VAPA_HUMAN relationship: location_of CCO:B0059035 ! CAC1I_HUMAN relationship: location_of CCO:B0059038 ! TAAR3_HUMAN relationship: location_of CCO:B0059039 ! TAAR2_HUMAN relationship: location_of CCO:B0059040 ! OR1A1_HUMAN relationship: location_of CCO:B0059045 ! SIRPG_HUMAN relationship: location_of CCO:B0059048 ! PLCE1_HUMAN relationship: location_of CCO:B0059061 ! GBG13_HUMAN relationship: location_of CCO:B0059074 ! XPR1_HUMAN relationship: location_of CCO:B0059076 ! P2RX2_HUMAN relationship: location_of CCO:B0059077 ! PEMT_HUMAN relationship: location_of CCO:B0059078 ! DHCR7_HUMAN relationship: location_of CCO:B0059079 ! TR10D_HUMAN relationship: location_of CCO:B0059082 ! CKLF_HUMAN relationship: location_of CCO:B0059086 ! SE1L1_HUMAN relationship: location_of CCO:B0059087 ! B4GT7_HUMAN relationship: location_of CCO:B0059091 ! CLN8_HUMAN relationship: location_of CCO:B0059102 ! Q9UDD7_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059110 ! VTI1B_HUMAN relationship: location_of CCO:B0059113 ! MARCO_HUMAN relationship: location_of CCO:B0059120 ! O14J1_HUMAN relationship: location_of CCO:B0059121 ! OR5V1_HUMAN relationship: location_of CCO:B0059122 ! O12D3_HUMAN relationship: location_of CCO:B0059131 ! MK1I1_HUMAN relationship: location_of CCO:B0059135 ! CNTP2_HUMAN relationship: location_of CCO:B0059146 ! CLC2D_HUMAN relationship: location_of CCO:B0059152 ! EMR2_HUMAN relationship: location_of CCO:B0059168 ! GP160_HUMAN relationship: location_of CCO:B0059169 ! Q9UJ49_HUMAN relationship: location_of CCO:B0059182 ! GBG8_HUMAN relationship: location_of CCO:B0059195 ! O52A1_HUMAN relationship: location_of CCO:B0059196 ! MUC12_HUMAN relationship: location_of CCO:B0059199 ! UR2R_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059202 ! TRHDE_HUMAN relationship: location_of CCO:B0059206 ! AMFR2_HUMAN relationship: location_of CCO:B0059214 ! RAB21_HUMAN relationship: location_of CCO:B0059221 ! RAB23_HUMAN relationship: location_of CCO:B0059223 ! KCNH3_HUMAN relationship: location_of CCO:B0059233 ! FZD4_HUMAN relationship: location_of CCO:B0059236 ! RAB26_HUMAN relationship: location_of CCO:B0059240 ! Q9UM77_HUMAN relationship: location_of CCO:B0059241 ! CLC4A_HUMAN relationship: location_of CCO:B0059244 ! GUC1B_HUMAN relationship: location_of CCO:B0059250 ! EDAR_HUMAN relationship: location_of CCO:B0059259 ! GPR34_HUMAN relationship: location_of CCO:B0059273 ! KCNH4_HUMAN relationship: location_of CCO:B0059276 ! CNTN6_HUMAN relationship: location_of CCO:B0059286 ! LAMP3_HUMAN relationship: location_of CCO:B0059296 ! TN13B_HUMAN relationship: location_of CCO:B0059297 ! VSIG4_HUMAN relationship: location_of CCO:B0059298 ! INVS_HUMAN relationship: location_of CCO:B0059302 ! CK009_HUMAN relationship: location_of CCO:B0059316 ! GPR52_HUMAN relationship: location_of CCO:B0059317 ! GPR55_HUMAN relationship: location_of CCO:B0059327 ! GPR89_HUMAN relationship: location_of CCO:B0059328 ! NSG2_HUMAN relationship: location_of CCO:B0059330 ! SIGL9_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0059335 ! GOT1B_HUMAN relationship: location_of CCO:B0059341 ! OR2W1_HUMAN relationship: location_of CCO:B0059343 ! GRIP1_HUMAN relationship: location_of CCO:B0059356 ! O10H1_HUMAN relationship: location_of CCO:B0059359 ! PLXD1_HUMAN relationship: location_of CCO:B0059362 ! RPGF2_HUMAN relationship: location_of CCO:B0059369 ! LRP12_HUMAN relationship: location_of CCO:B0059374 ! OR1A2_HUMAN relationship: location_of CCO:B0059379 ! HRH3_HUMAN relationship: location_of CCO:B0059380 ! O51B4_HUMAN relationship: location_of CCO:B0059381 ! O51B2_HUMAN relationship: location_of CCO:B0059386 ! NOX1_HUMAN relationship: location_of CCO:B0059387 ! TNR18_HUMAN relationship: location_of CCO:B0059392 ! NPFF2_HUMAN relationship: location_of CCO:B0059393 ! GPR44_HUMAN relationship: location_of CCO:B0059394 ! BACE2_HUMAN relationship: location_of CCO:B0059397 ! GPR56_HUMAN relationship: location_of CCO:B0059403 ! SAR1B_HUMAN relationship: location_of CCO:B0059412 ! STON1_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0061994 ! F173A_HUMAN relationship: location_of CCO:B0062769 ! EXOC7_HUMAN relationship: location_of CCO:B0062770 ! ZDHC3_HUMAN relationship: location_of CCO:B0062772 ! DD19A_HUMAN relationship: location_of CCO:B0062773 ! ITM2C_HUMAN relationship: location_of CCO:B0062774 ! S22AO_HUMAN relationship: location_of CCO:B0062780 ! NUP54_HUMAN relationship: location_of CCO:B0062787 ! STX8_HUMAN relationship: location_of CCO:B0062790 ! PLOD3_HUMAN relationship: location_of CCO:B0062791 ! NECP2_HUMAN relationship: location_of CCO:B0062798 ! BAMBI_HUMAN relationship: location_of CCO:B0062805 ! APBP2_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062824 ! AP2M1_HUMAN relationship: location_of CCO:B0062827 ! LRRN4_HUMAN relationship: location_of CCO:B0062832 ! EAA3_HUMAN relationship: location_of CCO:B0062839 ! TM147_HUMAN relationship: location_of CCO:B0062844 ! AQP5_HUMAN relationship: location_of CCO:B0062846 ! RN183_HUMAN relationship: location_of CCO:B0062852 ! KELL_HUMAN relationship: location_of CCO:B0062855 ! MFSD3_HUMAN relationship: location_of CCO:B0062858 ! SNP23_HUMAN relationship: location_of CCO:B0062861 ! NCS1_HUMAN relationship: location_of CCO:B0062866 ! CD177_HUMAN relationship: location_of CCO:B0062873 ! LIMS1_HUMAN relationship: location_of CCO:B0062879 ! CTSR1_HUMAN relationship: location_of CCO:B0062893 ! SAM50_HUMAN relationship: location_of CCO:B0062896 ! ZMY19_HUMAN relationship: location_of CCO:B0062902 ! NPDC1_HUMAN relationship: location_of CCO:B0062906 ! SERP2_HUMAN relationship: location_of CCO:B0062910 ! FATE1_HUMAN relationship: location_of CCO:B0062917 ! SNAA_HUMAN relationship: location_of CCO:B0062929 ! MALL_HUMAN relationship: location_of CCO:B0062933 ! TSN3_HUMAN relationship: location_of CCO:B0062937 ! CCD91_HUMAN relationship: location_of CCO:B0062940 ! LERL1_HUMAN relationship: location_of CCO:B0062941 ! NTNG2_HUMAN relationship: location_of CCO:B0062957 ! PHLA1_HUMAN relationship: location_of CCO:B0062962 ! KCMB1_HUMAN relationship: location_of CCO:B0062964 ! TEX28_HUMAN relationship: location_of CCO:B0062981 ! LAIR1_HUMAN relationship: location_of CCO:B0062986 ! VPS4A_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: location_of CCO:B0062990 ! SFXN3_HUMAN relationship: location_of CCO:B0062993 ! MDR1_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063007 ! ANTR2_HUMAN relationship: location_of CCO:B0063024 ! COG5_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063062 ! SFXN1_HUMAN relationship: location_of CCO:B0063067 ! CALX_HUMAN relationship: location_of CCO:B0063081 ! SSRD_HUMAN relationship: location_of CCO:B0063104 ! PLOD1_HUMAN relationship: location_of CCO:B0063133 ! BRI3B_HUMAN relationship: location_of CCO:B0063139 ! GSLG1_HUMAN relationship: location_of CCO:B0063145 ! CTLA4_HUMAN relationship: location_of CCO:B0063146 ! I10R1_HUMAN relationship: location_of CCO:B0063160 ! COMT_HUMAN relationship: location_of CCO:B0063164 ! CC136_HUMAN relationship: location_of CCO:B0063192 ! TRPC3_HUMAN relationship: location_of CCO:B0063197 ! MUC13_HUMAN relationship: location_of CCO:B0063198 ! SORL_HUMAN relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0063204 ! AP1B1_HUMAN relationship: location_of CCO:B0063205 ! TACD1_HUMAN relationship: location_of CCO:B0063222 ! OSTA_HUMAN relationship: location_of CCO:B0063227 ! MEP1B_HUMAN relationship: location_of CCO:B0063229 ! SCRB1_HUMAN relationship: location_of CCO:B0063239 ! ICAM3_HUMAN relationship: location_of CCO:B0063241 ! SNX18_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0063248 ! HA25_HUMAN relationship: location_of CCO:B0063249 ! HB25_HUMAN relationship: location_of CCO:B0063251 ! TIM44_HUMAN relationship: location_of CCO:B0063255 ! CN37_HUMAN relationship: location_of CCO:B0063256 ! TMM33_HUMAN relationship: location_of CCO:B0063258 ! VPS35_HUMAN relationship: location_of CCO:B0063267 ! ACCN1_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063273 ! GHR_HUMAN relationship: location_of CCO:B0063275 ! ZDHC7_HUMAN relationship: location_of CCO:B0063280 ! MYOTI_HUMAN relationship: location_of CCO:B0063288 ! B3GN9_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0063298 ! PPLA_HUMAN relationship: location_of CCO:B0063303 ! VPP2_HUMAN relationship: location_of CCO:B0063307 ! CLC4F_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063322 ! ENTP6_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0063334 ! ERG25_HUMAN relationship: location_of CCO:B0063336 ! SIA7F_HUMAN relationship: location_of CCO:B0063340 ! 2DRA_HUMAN relationship: location_of CCO:B0063349 ! PTN4_HUMAN relationship: location_of CCO:B0063351 ! TRPC7_HUMAN relationship: location_of CCO:B0063358 ! ADT1_HUMAN relationship: location_of CCO:B0063379 ! F134A_HUMAN relationship: location_of CCO:B0063384 ! MA2A2_HUMAN relationship: location_of CCO:B0063388 ! PEX2_HUMAN relationship: location_of CCO:B0063389 ! T4S1_HUMAN relationship: location_of CCO:B0063390 ! TMPS3_HUMAN relationship: location_of CCO:B0063391 ! UBE2B_HUMAN relationship: location_of CCO:B0063396 ! VAS1_HUMAN relationship: location_of CCO:B0063398 ! VPS11_HUMAN relationship: location_of CCO:B0063402 ! CI046_HUMAN relationship: location_of CCO:B0063411 ! F176A_HUMAN relationship: location_of CCO:B0063423 ! NDUB9_HUMAN relationship: location_of CCO:B0063424 ! NDUV2_HUMAN relationship: location_of CCO:B0063432 ! RER1_HUMAN relationship: location_of CCO:B0063433 ! EDEM2_HUMAN relationship: location_of CCO:B0063442 ! TUTLA_HUMAN relationship: location_of CCO:B0063443 ! LIPL_HUMAN relationship: location_of CCO:B0063449 ! STT3A_HUMAN relationship: location_of CCO:B0063454 ! CD48_HUMAN relationship: location_of CCO:B0063455 ! EPCR_HUMAN relationship: location_of CCO:B0063459 ! GOLI_HUMAN relationship: location_of CCO:B0063471 ! TM216_HUMAN relationship: location_of CCO:B0063476 ! PTHD2_HUMAN relationship: location_of CCO:B0063478 ! FXYD3_HUMAN relationship: location_of CCO:B0063481 ! PIGC_HUMAN relationship: location_of CCO:B0063486 ! PRRT2_HUMAN relationship: location_of CCO:B0063491 ! SPRN_HUMAN relationship: location_of CCO:B0063495 ! S2538_HUMAN relationship: location_of CCO:B0063503 ! QCR8_HUMAN relationship: location_of CCO:B0063504 ! CAH12_HUMAN relationship: location_of CCO:B0063507 ! LY6H_HUMAN relationship: location_of CCO:B0063516 ! M6PBP_HUMAN relationship: location_of CCO:B0063527 ! CDAN1_HUMAN relationship: location_of CCO:B0063531 ! CLCB_HUMAN relationship: location_of CCO:B0063532 ! APMAP_HUMAN relationship: location_of CCO:B0063545 ! ARHGB_HUMAN-Phosphoserine663 relationship: location_of CCO:B0063552 ! ARHGC_HUMAN-Phosphoserine1288 relationship: location_of CCO:B0063598 ! ARMS_HUMAN-Phosphoserine918 relationship: location_of CCO:B0063640 ! AT10A_HUMAN-Phosphoserine646 relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: location_of CCO:B0063685 ! AVEN_HUMAN-Phosphoserine94 relationship: location_of CCO:B0063708 ! BAI3_HUMAN-Phosphoserine1220 relationship: location_of CCO:B0063711 ! BAIP2_HUMAN-Phosphothreonine296 relationship: location_of CCO:B0063733 ! BASI_HUMAN-Phosphoserine362 relationship: location_of CCO:B0063865 ! BCLW_HUMAN-Phosphoserine192 relationship: location_of CCO:B0063920 ! BIG2_HUMAN-Phosphoserine1514 relationship: location_of CCO:B0063923 ! BIG3_HUMAN-Phosphoserine1651 relationship: location_of CCO:B0063924 ! BIM_HUMAN-Phosphoserine77 relationship: location_of CCO:B0063939 ! BLNK_HUMAN-Phosphotyrosine178 relationship: location_of CCO:B0063952 ! BORG2_HUMAN-Phosphoserine89 relationship: location_of CCO:B0063956 ! BORG4_HUMAN-Phosphoserine138 relationship: location_of CCO:B0063964 ! BORG5_HUMAN-Phosphoserine121 relationship: location_of CCO:B0064015 ! BTK_HUMAN-Phosphotyrosine344 relationship: location_of CCO:B0064022 ! C3AR_HUMAN-Sulfotyrosine174 relationship: location_of CCO:B0064025 ! C5ARL_HUMAN-Phosphoserine326 relationship: location_of CCO:B0064030 ! C5AR_HUMAN-Phosphoserine327 relationship: location_of CCO:B0064043 ! CAC1D_HUMAN-Phosphoserine1475 relationship: location_of CCO:B0064045 ! CACB3_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0064059 ! CAP1_HUMAN-Phosphoserine290 relationship: location_of CCO:B0064121 ! CCR10_HUMAN-Phosphothreonine295 relationship: location_of CCO:B0064123 ! CCR2_HUMAN-Sulfotyrosine26 relationship: location_of CCO:B0064135 ! CD19_HUMAN-Phosphotyrosine378 relationship: location_of CCO:B0064139 ! CD226_HUMAN-Phosphoserine290 relationship: location_of CCO:B0064141 ! CD244_HUMAN-Phosphotyrosine271 relationship: location_of CCO:B0064151 ! CD33_HUMAN-Phosphotyrosine340 relationship: location_of CCO:B0064154 ! CD3D_HUMAN-Phosphotyrosine160 relationship: location_of CCO:B0064160 ! CD3G_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0064164 ! CD3Z_HUMAN-Phosphotyrosine83 relationship: location_of CCO:B0064171 ! CD5_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0064255 ! CELR1_HUMAN-Phosphoserine2761 relationship: location_of CCO:B0064259 ! CEND2_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0064358 ! CIP4_HUMAN-Phosphoserine335 relationship: location_of CCO:B0064367 ! CKAP4_HUMAN-Phosphoserine312 relationship: location_of CCO:B0064377 ! CLC1B_HUMAN-Phosphotyrosine7 relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064391 ! CLN6_HUMAN-Phosphoserine31 relationship: location_of CCO:B0064416 ! CNKR1_HUMAN-Phosphoserine305 relationship: location_of CCO:B0064419 ! CNKR2_HUMAN-Phosphoserine248 relationship: location_of CCO:B0064430 ! CNTP1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0064448 ! COG3_HUMAN-Phosphoserine533 relationship: location_of CCO:B0064449 ! CPEB1_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0064451 ! CPLX4_HUMAN-Cysteine methyl ester157 relationship: location_of CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064461 ! CR3L3_HUMAN-Phosphoserine256 relationship: location_of CCO:B0064467 ! CRIM1_HUMAN-Phosphothreonine1035 relationship: location_of CCO:B0064473 ! CRK_HUMAN-Phosphoserine41 relationship: location_of CCO:B0064552 ! CSF1R_HUMAN-Phosphothreonine562 relationship: location_of CCO:B0064565 ! CSPG4_HUMAN-Phosphothreonine21 relationship: location_of CCO:B0064587 ! CTNL1_HUMAN-Phosphoserine538 relationship: location_of CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: location_of CCO:B0064623 ! DAB2_HUMAN-Phosphoserine401 relationship: location_of CCO:B0064624 ! DAD1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0064632 ! DAPP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0064683 ! DD19B_HUMAN-Phosphoserine86 relationship: location_of CCO:B0064685 ! DDEF1_HUMAN-Phosphoserine839 relationship: location_of CCO:B0064689 ! DDEF2_HUMAN-Phosphoserine701 relationship: location_of CCO:B0064741 ! DERL1_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0064772 ! DLGP4_HUMAN-Phosphoserine378 relationship: location_of CCO:B0064792 ! DNER_HUMAN-Phosphotyrosine718 relationship: location_of CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: location_of CCO:B0064897 ! DTL_HUMAN-Phosphoserine676 relationship: location_of CCO:B0065046 ! EM55_HUMAN-Phosphoserine19 relationship: location_of CCO:B0065089 ! EPHB3_HUMAN-Phosphotyrosine600 relationship: location_of CCO:B0065098 ! EPOR_HUMAN-Phosphotyrosine504 relationship: location_of CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 relationship: location_of CCO:B0065165 ! ETBR2_HUMAN-Phosphoserine471 relationship: location_of CCO:B0065229 ! AA3R_HUMAN-Phosphoserine317 relationship: location_of CCO:B0065230 ! AAAT_HUMAN-Phosphoserine535 relationship: location_of CCO:B0065266 ! ABCA2_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0065314 ! ACCN3_HUMAN-Phosphoserine521 relationship: location_of CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: location_of CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0065403 ! ADA_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065404 ! ADCY5_HUMAN-Phosphoserine8 relationship: location_of CCO:B0065406 ! ADCY6_HUMAN-Phosphoserine576 relationship: location_of CCO:B0065409 ! ADCY9_HUMAN-Phosphoserine610 relationship: location_of CCO:B0065410 ! ADCYA_HUMAN-Phosphothreonine809 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0065450 ! ADT3_HUMAN-N-acetylthreonine2 relationship: location_of CCO:B0065565 ! AKP13_HUMAN-Phosphoserine1929 relationship: location_of CCO:B0065648 ! ANTR1_HUMAN-Phosphotyrosine425 relationship: location_of CCO:B0065658 ! AP1M1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: location_of CCO:B0065667 ! AP3B1_HUMAN-Phosphoserine609 relationship: location_of CCO:B0065672 ! AP3D1_HUMAN-Phosphoserine759 relationship: location_of CCO:B0065681 ! APBA3_HUMAN-Phosphoserine372 relationship: location_of CCO:B0065704 ! ARFG2_HUMAN-Phosphoserine498 relationship: location_of CCO:B0065705 ! ARFG3_HUMAN-Phosphoserine143 relationship: location_of CCO:B0065758 ! ATPK_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0065764 ! ATPO_HUMAN-N6-acetyllysine176 relationship: location_of CCO:B0065783 ! ATX2L_HUMAN-Phosphoserine559 relationship: location_of CCO:B0065801 ! C1QBP_HUMAN-Phosphoserine201 relationship: location_of CCO:B0065810 ! CAD10_HUMAN-Phosphoserine784 relationship: location_of CCO:B0065817 ! CALY_HUMAN-Phosphotyrosine151 relationship: location_of CCO:B0065843 ! CD22_HUMAN-Phosphotyrosine762 relationship: location_of CCO:B0065880 ! CLD12_HUMAN-Phosphoserine228 relationship: location_of CCO:B0065888 ! COG4_HUMAN-Phosphotyrosine714 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: location_of CCO:B0065958 ! DOCK2_HUMAN-Phosphoserine1706 relationship: location_of CCO:B0066003 ! EMD_HUMAN-Phosphotyrosine105 relationship: location_of CCO:B0066008 ! ENOX1_HUMAN-Phosphoserine403 relationship: location_of CCO:B0066010 ! EPN1_HUMAN-Phosphoserine395 relationship: location_of CCO:B0066020 ! EPN4_HUMAN-Phosphoserine232 relationship: location_of CCO:B0066029 ! ESYT1_HUMAN-Phosphoserine1034 relationship: location_of CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: location_of CCO:B0066149 ! FCERG_HUMAN-Phosphotyrosine76 relationship: location_of CCO:B0066152 ! FCGR1_HUMAN-Phosphotyrosine138 relationship: location_of CCO:B0066173 ! FFAR1_HUMAN-Phosphotyrosine44 relationship: location_of CCO:B0066213 ! FLNC_HUMAN-Phosphotyrosine2683 relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0066281 ! FRS2_HUMAN-Phosphothreonine288 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0066324 ! FYN_HUMAN-Phosphotyrosine213 relationship: location_of CCO:B0066332 ! FYV1_HUMAN-Phosphotyrosine1772 relationship: location_of CCO:B0066377 ! GAPD1_HUMAN-Phosphoserine966 relationship: location_of CCO:B0066399 ! GBG12_HUMAN-Phosphotyrosine42 relationship: location_of CCO:B0066401 ! GBG2_HUMAN-Phosphothreonine52 relationship: location_of CCO:B0066437 ! GDIB_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066489 ! GNAS1_HUMAN-ADP-ribosylarginine844 relationship: location_of CCO:B0066508 ! GOGB1_HUMAN-Phosphoserine17 relationship: location_of CCO:B0066524 ! GP125_HUMAN-Phosphothreonine208 relationship: location_of CCO:B0066526 ! GP126_HUMAN-Phosphoserine1165 relationship: location_of CCO:B0066528 ! GP155_HUMAN-Phosphotyrosine451 relationship: location_of CCO:B0066536 ! GP1BB_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 relationship: location_of CCO:B0066544 ! GPR12_HUMAN-Phosphoserine332 relationship: location_of CCO:B0066549 ! GPR6_HUMAN-Phosphoserine356 relationship: location_of CCO:B0066552 ! GPSM1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0066584 ! GRB14_HUMAN-Phosphoserine372 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066606 ! GRIA2_HUMAN-Phosphoserine880 relationship: location_of CCO:B0066608 ! GRIA3_HUMAN-Phosphotyrosine887 relationship: location_of CCO:B0066623 ! GRK7_HUMAN-Cysteine methyl ester550 relationship: location_of CCO:B0066627 ! GRM1_HUMAN-Phosphotyrosine1109 relationship: location_of CCO:B0066629 ! GRP1_HUMAN-Phosphothreonine184 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0066768 ! HCK_HUMAN-Phosphotyrosine209 relationship: location_of CCO:B0066889 ! HOME3_HUMAN-Phosphoserine159 relationship: location_of CCO:B0066895 ! HRH1_HUMAN-Phosphoserine275 relationship: location_of CCO:B0066966 ! HXK1_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0067062 ! IGSF8_HUMAN-Phosphoserine12 relationship: location_of CCO:B0067075 ! IL2RG_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0067079 ! IL4RA_HUMAN-Phosphotyrosine631 relationship: location_of CCO:B0067081 ! IL7RA_HUMAN-Phosphotyrosine169 relationship: location_of CCO:B0067093 ! INADL_HUMAN-Phosphoserine455 relationship: location_of CCO:B0067099 ! INAR1_HUMAN-Phosphotyrosine481 relationship: location_of CCO:B0067114 ! INGR1_HUMAN-Phosphoserine369 relationship: location_of CCO:B0067115 ! INGR2_HUMAN-Phosphoserine198 relationship: location_of CCO:B0067120 ! INSRR_HUMAN-Phosphotyrosine1145 relationship: location_of CCO:B0067159 ! ITA4_HUMAN-Phosphoserine1021 relationship: location_of CCO:B0067163 ! ITK_HUMAN-Phosphoserine565 relationship: location_of CCO:B0067166 ! ITPR1_HUMAN-Phosphoserine1598 relationship: location_of CCO:B0067170 ! ITPR2_HUMAN-Phosphotyrosine2607 relationship: location_of CCO:B0067173 ! ITPR3_HUMAN-Phosphoserine1832 relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: location_of CCO:B0067243 ! K2018_HUMAN-Phosphoserine1775 relationship: location_of CCO:B0067282 ! KCD15_HUMAN-Phosphoserine35 relationship: location_of CCO:B0067285 ! KCIP2_HUMAN-Phosphotyrosine111 relationship: location_of CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 relationship: location_of CCO:B0067295 ! KCNH7_HUMAN-Phosphoserine353 relationship: location_of CCO:B0067366 ! KIT_HUMAN-Phosphotyrosine703 relationship: location_of CCO:B0067418 ! KPCD_HUMAN-Phosphoserine307 relationship: location_of CCO:B0067493 ! KS6C1_HUMAN-Phosphoserine640 relationship: location_of CCO:B0067499 ! KSR1_HUMAN-Phosphoserine567 relationship: location_of CCO:B0067513 ! KTN1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0067553 ! LAP4_HUMAN-Phosphoserine1223 relationship: location_of CCO:B0067581 ! LAT_HUMAN-Phosphoserine84 relationship: location_of CCO:B0067594 ! LAX1_HUMAN-Phosphotyrosine373 relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: location_of CCO:B0067643 ! LGR6_HUMAN-Phosphoserine457 relationship: location_of CCO:B0067681 ! LIRB3_HUMAN-Phosphothreonine480 relationship: location_of CCO:B0067727 ! LMNB1_HUMAN-Phosphothreonine575 relationship: location_of CCO:B0067765 ! LPHN1_HUMAN-Phosphoserine1377 relationship: location_of CCO:B0067770 ! LPHN3_HUMAN-Phosphothreonine1445 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0067794 ! LTK_HUMAN-Phosphotyrosine672 relationship: location_of CCO:B0067845 ! MADD_HUMAN-Phosphoserine921 relationship: location_of CCO:B0067849 ! MAGD1_HUMAN-Phosphotyrosine92 relationship: location_of CCO:B0067856 ! MAGI2_HUMAN-Phosphotyrosine827 relationship: location_of CCO:B0067998 ! MAST2_HUMAN-Phosphoserine74 relationship: location_of CCO:B0068019 ! MAVS_HUMAN-Phosphothreonine398 relationship: location_of CCO:B0068055 ! MCF2_HUMAN-Phosphoserine742 relationship: location_of CCO:B0068058 ! MCL1_HUMAN-Phosphothreonine163 relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: location_of CCO:B0068070 ! MCTP2_HUMAN-Phosphoserine145 relationship: location_of CCO:B0068148 ! MERTK_HUMAN-Phosphotyrosine754 relationship: location_of CCO:B0068168 ! MIA3_HUMAN-Phosphoserine1906 relationship: location_of CCO:B0068239 ! MLXIP_HUMAN-Phosphoserine27 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068447 ! NBEA_HUMAN-Phosphoserine1529 relationship: location_of CCO:B0068521 ! NCPR_HUMAN-Phosphotyrosine575 relationship: location_of CCO:B0068532 ! NDRG1_HUMAN-Phosphoserine330 relationship: location_of CCO:B0068547 ! NDUA6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068548 ! NDUA7_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068554 ! NDUV1_HUMAN-N6-acetyllysine81 relationship: location_of CCO:B0068580 ! NEUM_HUMAN-Phosphoserine41 relationship: location_of CCO:B0068634 ! NFAM1_HUMAN-Phosphotyrosine231 relationship: location_of CCO:B0068697 ! NFXL1_HUMAN-Phosphoserine107 relationship: location_of CCO:B0068704 ! NGEF_HUMAN-Phosphotyrosine179 relationship: location_of CCO:B0068709 ! NHERF_HUMAN-Phosphoserine288 relationship: location_of CCO:B0068715 ! NHRF2_HUMAN-Phosphoserine183 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0068796 ! NOSTN_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0068815 ! NPHN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0068828 ! NRBP_HUMAN-Phosphothreonine441 relationship: location_of CCO:B0068836 ! NRG3_HUMAN-Phosphoserine119 relationship: location_of CCO:B0068876 ! NTAL_HUMAN-Phosphotyrosine233 relationship: location_of CCO:B0068879 ! NTRK1_HUMAN-Phosphotyrosine680 relationship: location_of CCO:B0068884 ! NTRK2_HUMAN-Phosphotyrosine706 relationship: location_of CCO:B0068888 ! NTRK3_HUMAN-Phosphotyrosine705 relationship: location_of CCO:B0068941 ! NUP98_HUMAN-Phosphoserine1060 relationship: location_of CCO:B0068951 ! O52E8_HUMAN-Phosphoserine144 relationship: location_of CCO:B0068952 ! O56A3_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0068967 ! OGFR_HUMAN-Phosphoserine484 relationship: location_of CCO:B0068975 ! OPSD_HUMAN-Phosphoserine343 relationship: location_of CCO:B0068982 ! OR4S2_HUMAN-Phosphoserine227 relationship: location_of CCO:B0068996 ! OSMR_HUMAN-Phosphotyrosine837 relationship: location_of CCO:B0069007 ! OX1R_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0069014 ! P2RX5_HUMAN-Phosphotyrosine55 relationship: location_of CCO:B0069015 ! P2RX6_HUMAN-Phosphotyrosine54 relationship: location_of CCO:B0069016 ! P2RX7_HUMAN-Phosphotyrosine343 relationship: location_of CCO:B0069018 ! P2RY1_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069020 ! P2RY4_HUMAN-Phosphoserine334 relationship: location_of CCO:B0069042 ! PA24C_HUMAN-Cysteine methyl ester538 relationship: location_of CCO:B0069049 ! PACN3_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069056 ! PAG1_HUMAN-Phosphotyrosine227 relationship: location_of CCO:B0069065 ! PAK2_HUMAN-Phosphoserine58 relationship: location_of CCO:B0069078 ! PALM2_HUMAN-Phosphoserine318 relationship: location_of CCO:B0069080 ! PALMD_HUMAN-Phosphoserine135 relationship: location_of CCO:B0069088 ! PALM_HUMAN-Phosphothreonine158 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0069166 ! PDE3A_HUMAN-Phosphothreonine440 relationship: location_of CCO:B0069168 ! PDE3B_HUMAN-Phosphoserine442 relationship: location_of CCO:B0069171 ! PDE4A_HUMAN-Phosphoserine686 relationship: location_of CCO:B0069178 ! PDE4D_HUMAN-Phosphoserine18 relationship: location_of CCO:B0069184 ! PDE6A_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0069194 ! PDZD1_HUMAN-Phosphoserine514 relationship: location_of CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 relationship: location_of CCO:B0069237 ! PEX14_HUMAN-Phosphoserine335 relationship: location_of CCO:B0069245 ! PHB2_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0069291 ! PI2R_HUMAN-Cysteine methyl ester383 relationship: location_of CCO:B0069292 ! PI42B_HUMAN-Phosphotyrosine98 relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: location_of CCO:B0069329 ! PKD1_HUMAN-Phosphoserine4288 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0069392 ! PLCD3_HUMAN-Phosphoserine105 relationship: location_of CCO:B0069399 ! PLCH2_HUMAN-Phosphoserine605 relationship: location_of CCO:B0069412 ! PLEK2_HUMAN-Phosphotyrosine333 relationship: location_of CCO:B0069421 ! PLXA1_HUMAN-Phosphotyrosine122 relationship: location_of CCO:B0069422 ! PLXA2_HUMAN-Phosphoserine1645 relationship: location_of CCO:B0069425 ! PLXA3_HUMAN-Phosphoserine1610 relationship: location_of CCO:B0069566 ! PSD3_HUMAN-Phosphoserine1011 relationship: location_of CCO:B0069587 ! PTAD1_HUMAN-Phosphoserine114 relationship: location_of CCO:B0069601 ! PTN1_HUMAN-Phosphoserine386 relationship: location_of CCO:B0069605 ! PTRF_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069640 ! PVRL2_HUMAN-Phosphoserine433 relationship: location_of CCO:B0069663 ! RAB12_HUMAN-Phosphoserine25 relationship: location_of CCO:B0069665 ! RAB13_HUMAN-Phosphoserine178 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0069670 ! RAB15_HUMAN-Cysteine methyl ester212 relationship: location_of CCO:B0069671 ! RAB18_HUMAN-Phosphothreonine29 relationship: location_of CCO:B0069673 ! RAB1B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0069680 ! RAB3A_HUMAN-Phosphoserine188 relationship: location_of CCO:B0069683 ! RAB3B_HUMAN-Cysteine methyl ester219 relationship: location_of CCO:B0069686 ! RAB42_HUMAN-Cysteine methyl ester105 relationship: location_of CCO:B0069688 ! RAB43_HUMAN-Cysteine methyl ester212 relationship: location_of CCO:B0069690 ! RAB6A_HUMAN-N-acetylserine2 relationship: location_of CCO:B0069693 ! RAB6B_HUMAN-Cysteine methyl ester208 relationship: location_of CCO:B0069705 ! RAC3_HUMAN-Cysteine methyl ester189 relationship: location_of CCO:B0069720 ! RAI3_HUMAN-Phosphotyrosine347 relationship: location_of CCO:B0069748 ! RASA3_HUMAN-Phosphoserine809 relationship: location_of CCO:B0069749 ! RASD1_HUMAN-S-nitrosocysteine11 relationship: location_of CCO:B0069757 ! RB27B_HUMAN-Cysteine methyl ester218 relationship: location_of CCO:B0069759 ! RB33B_HUMAN-Cysteine methyl ester229 relationship: location_of CCO:B0069760 ! RB39A_HUMAN-Cysteine methyl ester217 relationship: location_of CCO:B0069761 ! RB39B_HUMAN-Cysteine methyl ester213 relationship: location_of CCO:B0069763 ! RB6I2_HUMAN-Phosphoserine17 relationship: location_of CCO:B0069831 ! RBP1_HUMAN-Phosphoserine93 relationship: location_of CCO:B0069839 ! RCAS1_HUMAN-Phosphothreonine41 relationship: location_of CCO:B0069901 ! RFRP_HUMAN-Phenylalanine amide131 relationship: location_of CCO:B0069921 ! RGRF2_HUMAN-Phosphoserine737 relationship: location_of CCO:B0069933 ! RHG05_HUMAN-Phosphoserine1124 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0070012 ! RHOH_HUMAN-Cysteine methyl ester188 relationship: location_of CCO:B0070013 ! RHOJ_HUMAN-Cysteine methyl ester211 relationship: location_of CCO:B0070014 ! RHOQ_HUMAN-Cysteine methyl ester202 relationship: location_of CCO:B0070062 ! RK_HUMAN-Cysteine methyl ester560 relationship: location_of CCO:B0070101 ! RN139_HUMAN-Phosphoserine625 relationship: location_of CCO:B0070125 ! ROBO1_HUMAN-Phosphotyrosine1038 relationship: location_of CCO:B0070132 ! ROCK1_HUMAN-Phosphothreonine1180 relationship: location_of CCO:B0070139 ! RON_HUMAN-Phosphotyrosine1360 relationship: location_of CCO:B0070144 ! ROR2_HUMAN-Phosphotyrosine646 relationship: location_of CCO:B0070161 ! RPE65_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070172 ! RPGF6_HUMAN-Phosphothreonine1507 relationship: location_of CCO:B0070249 ! RSLAB_HUMAN-Cysteine methyl ester200 relationship: location_of CCO:B0070259 ! RTN1_HUMAN-Phosphoserine487 relationship: location_of CCO:B0070260 ! RTN2_HUMAN-Phosphoserine44 relationship: location_of CCO:B0070272 ! RYR2_HUMAN-Phosphoserine2806 relationship: location_of CCO:B0070277 ! S20A1_HUMAN-Phosphoserine265 relationship: location_of CCO:B0070283 ! S35B2_HUMAN-Phosphoserine427 relationship: location_of CCO:B0070285 ! S35E1_HUMAN-Phosphoserine363 relationship: location_of CCO:B0070287 ! S38A3_HUMAN-Phosphoserine54 relationship: location_of CCO:B0070338 ! SC16A_HUMAN-Phosphoserine1905 relationship: location_of CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070370 ! SEM4D_HUMAN-Phosphoserine195 relationship: location_of CCO:B0070377 ! SERC3_HUMAN-Phosphoserine371 relationship: location_of CCO:B0070469 ! SH2B2_HUMAN-Phosphotyrosine629 relationship: location_of CCO:B0070472 ! SH2D3_HUMAN-Phosphotyrosine283 relationship: location_of CCO:B0070479 ! SHAN2_HUMAN-Phosphoserine1113 relationship: location_of CCO:B0070486 ! SHAN3_HUMAN-Phosphoserine783 relationship: location_of CCO:B0070494 ! SHB_HUMAN-Phosphoserine314 relationship: location_of CCO:B0070505 ! SHIP1_HUMAN-Phosphotyrosine944 relationship: location_of CCO:B0070510 ! SHPS1_HUMAN-Phosphotyrosine495 relationship: location_of CCO:B0070556 ! SIT1_HUMAN-Phosphotyrosine127 relationship: location_of CCO:B0070565 ! SKAP1_HUMAN-Phosphotyrosine142 relationship: location_of CCO:B0070575 ! SLAF1_HUMAN-Phosphotyrosine281 relationship: location_of CCO:B0070676 ! SNAG_HUMAN-Phosphoserine284 relationship: location_of CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 relationship: location_of CCO:B0070697 ! SNTA1_HUMAN-Phosphoserine189 relationship: location_of CCO:B0070704 ! SNTB1_HUMAN-Phosphoserine389 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: location_of CCO:B0070716 ! SNX17_HUMAN-Phosphoserine437 relationship: location_of CCO:B0070843 ! SPY4_HUMAN-Phosphoserine125 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0070950 ! STABP_HUMAN-Phosphoserine245 relationship: location_of CCO:B0070960 ! STAM2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0070979 ! STRN4_HUMAN-Phosphoserine276 relationship: location_of CCO:B0070985 ! STX12_HUMAN-Phosphoserine142 relationship: location_of CCO:B0070992 ! STXB1_HUMAN-Phosphothreonine346 relationship: location_of CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: location_of CCO:B0071062 ! SYNJ2_HUMAN-Phosphotyrosine130 relationship: location_of CCO:B0071075 ! TAB2_HUMAN-Phosphoserine372 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0071220 ! TBC9B_HUMAN-Phosphoserine411 relationship: location_of CCO:B0071324 ! TEN1_HUMAN-Phosphoserine2580 relationship: location_of CCO:B0071331 ! TENC1_HUMAN-Phosphoserine835 relationship: location_of CCO:B0071350 ! TEX2_HUMAN-Phosphothreonine269 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071386 ! THS7A_HUMAN-Phosphotyrosine1341 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071420 ! TLR7_HUMAN-Phosphoserine1010 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 relationship: location_of CCO:B0071432 ! TMM22_HUMAN-Phosphoserine409 relationship: location_of CCO:B0071433 ! TMM51_HUMAN-Phosphoserine115 relationship: location_of CCO:B0071437 ! TNAP1_HUMAN-Phosphoserine280 relationship: location_of CCO:B0071442 ! TNR11_HUMAN-Phosphoserine463 relationship: location_of CCO:B0071447 ! TOM1_HUMAN-Phosphoserine176 relationship: location_of CCO:B0071490 ! TR10A_HUMAN-Phosphoserine83 relationship: location_of CCO:B0071584 ! TRPC6_HUMAN-Phosphoserine815 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 relationship: location_of CCO:B0071644 ! TYOBP_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0071646 ! TYRO3_HUMAN-Phosphotyrosine686 relationship: location_of CCO:B0071732 ! UN13A_HUMAN-Phosphoserine245 relationship: location_of CCO:B0071733 ! UN13B_HUMAN-Phosphothreonine605 relationship: location_of CCO:B0071734 ! UNC5C_HUMAN-Phosphotyrosine568 relationship: location_of CCO:B0071735 ! UNC5D_HUMAN-Phosphothreonine210 relationship: location_of CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 relationship: location_of CCO:B0071778 ! VASP_HUMAN-Phosphotyrosine39 relationship: location_of CCO:B0071808 ! VIPR1_HUMAN-Phosphoserine449 relationship: location_of CCO:B0071842 ! WFS1_HUMAN-Phosphoserine32 relationship: location_of CCO:B0071946 ! ZA2G_HUMAN-Pyrrolidone carboxylic acid18 relationship: location_of CCO:B0072026 ! ZFY16_HUMAN-Phosphoserine815 relationship: location_of CCO:B0072275 ! ZO3_HUMAN-Phosphoserine579 [Term] id: CCO:C0000767 name: integral to membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane." [GOC:go_curators] subset: gosubset_prok synonym: "transmembrane" EXACT [] xref: GO:0016021 is_a: CCO:C0001148 ! intrinsic to membrane relationship: location_of CCO:B0001362 ! EREG_HUMAN relationship: location_of CCO:B0001406 ! ADCY3_HUMAN relationship: location_of CCO:B0001428 ! ERN1_HUMAN relationship: location_of CCO:B0001448 ! TNF15_HUMAN relationship: location_of CCO:B0001470 ! EGF_HUMAN relationship: location_of CCO:B0001473 ! TNFB_HUMAN relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0001477 ! IL2RA_HUMAN relationship: location_of CCO:B0001517 ! IFM1_HUMAN relationship: location_of CCO:B0001557 ! PAR1_HUMAN relationship: location_of CCO:B0001590 ! BTC_HUMAN relationship: location_of CCO:B0001666 ! HRSL3_HUMAN relationship: location_of CCO:B0001719 ! NOTC2_HUMAN relationship: location_of CCO:B0001723 ! BAX_HUMAN relationship: location_of CCO:B0001765 ! PTC1_HUMAN relationship: location_of CCO:B0001767 ! BMPR2_HUMAN relationship: location_of CCO:B0001806 ! DHC24_HUMAN relationship: location_of CCO:B0001818 ! EXT1_HUMAN relationship: location_of CCO:B0001903 ! STEA3_HUMAN relationship: location_of CCO:B0001922 ! TM11A_HUMAN relationship: location_of CCO:B0001928 ! ERN2_HUMAN relationship: location_of CCO:B0001940 ! CUZD1_HUMAN relationship: location_of CCO:B0001978 ! PPC1B_HUMAN relationship: location_of CCO:B0001983 ! CADM4_HUMAN relationship: location_of CCO:B0002028 ! EXT2_HUMAN relationship: location_of CCO:B0002110 ! CADM1_HUMAN relationship: location_of CCO:B0002135 ! PIGU_HUMAN relationship: location_of CCO:B0002175 ! NSMA2_HUMAN relationship: location_of CCO:B0002236 ! GP132_HUMAN relationship: location_of CCO:B0002245 ! JAG2_HUMAN relationship: location_of CCO:B0005247 ! CHST1_HUMAN relationship: location_of CCO:B0005282 ! NOC4L_HUMAN relationship: location_of CCO:B0005312 ! PEX26_HUMAN relationship: location_of CCO:B0005325 ! IL1R1_HUMAN relationship: location_of CCO:B0005374 ! APLP2_HUMAN relationship: location_of CCO:B0005421 ! BIK_HUMAN relationship: location_of CCO:B0005445 ! SDC2_HUMAN relationship: location_of CCO:B0005447 ! NRP1_HUMAN relationship: location_of CCO:B0005450 ! ICAM1_HUMAN relationship: location_of CCO:B0005455 ! CD166_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005479 ! TNR6_HUMAN relationship: location_of CCO:B0005498 ! CREB3_HUMAN relationship: location_of CCO:B0005506 ! FSHR_HUMAN relationship: location_of CCO:B0005534 ! TNR1A_HUMAN relationship: location_of CCO:B0005535 ! TNR1B_HUMAN relationship: location_of CCO:B0005543 ! AVR2A_HUMAN relationship: location_of CCO:B0005545 ! NRX1A_HUMAN relationship: location_of CCO:B0005546 ! CELR3_HUMAN relationship: location_of CCO:B0005547 ! PLXB3_HUMAN relationship: location_of CCO:B0005549 ! MEG10_HUMAN relationship: location_of CCO:B0005571 ! BAT5_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005618 ! TRBM_HUMAN relationship: location_of CCO:B0005624 ! SCAM1_HUMAN relationship: location_of CCO:B0005628 ! ALK_HUMAN relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0005692 ! CAC1C_HUMAN relationship: location_of CCO:B0005707 ! TNR14_HUMAN relationship: location_of CCO:B0005723 ! MTR1A_HUMAN relationship: location_of CCO:B0005724 ! MTR1B_HUMAN relationship: location_of CCO:B0005740 ! CD4_HUMAN relationship: location_of CCO:B0005760 ! NEP_HUMAN relationship: location_of CCO:B0005845 ! LRC59_HUMAN relationship: location_of CCO:B0005868 ! FGFR1_HUMAN relationship: location_of CCO:B0005870 ! TGFA_HUMAN relationship: location_of CCO:B0005889 ! TAP1_HUMAN relationship: location_of CCO:B0005901 ! BCLX_HUMAN relationship: location_of CCO:B0005906 ! ERBB4_HUMAN relationship: location_of CCO:B0005928 ! VRK2_HUMAN relationship: location_of CCO:B0005957 ! MEGF8_HUMAN relationship: location_of CCO:B0005974 ! NOTC1_HUMAN relationship: location_of CCO:B0005993 ! TXD11_HUMAN relationship: location_of CCO:B0006004 ! CSMD1_HUMAN relationship: location_of CCO:B0006010 ! TNR8_HUMAN relationship: location_of CCO:B0006019 ! LPP3_HUMAN relationship: location_of CCO:B0006022 ! PCDH9_HUMAN relationship: location_of CCO:B0006023 ! T3JAM_HUMAN relationship: location_of CCO:B0006024 ! EPHB6_HUMAN relationship: location_of CCO:B0006029 ! PANX3_HUMAN relationship: location_of CCO:B0006039 ! SMO_HUMAN relationship: location_of CCO:B0006099 ! PCDA4_HUMAN relationship: location_of CCO:B0006104 ! PTPRS_HUMAN relationship: location_of CCO:B0006116 ! TOM20_HUMAN relationship: location_of CCO:B0006132 ! CREL1_HUMAN relationship: location_of CCO:B0006141 ! FXYD6_HUMAN relationship: location_of CCO:B0006164 ! STX5_HUMAN relationship: location_of CCO:B0006179 ! APLP1_HUMAN relationship: location_of CCO:B0006201 ! IMMT_HUMAN relationship: location_of CCO:B0006259 ! BOC_HUMAN relationship: location_of CCO:B0006262 ! CD81_HUMAN relationship: location_of CCO:B0006268 ! ABCD4_HUMAN relationship: location_of CCO:B0006273 ! GPAA1_HUMAN relationship: location_of CCO:B0006285 ! GRIK5_HUMAN relationship: location_of CCO:B0006287 ! ERG28_HUMAN relationship: location_of CCO:B0006292 ! PLXB2_HUMAN relationship: location_of CCO:B0006306 ! GP135_HUMAN relationship: location_of CCO:B0006313 ! SRPRB_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0006318 ! ITAE_HUMAN relationship: location_of CCO:B0006320 ! CHSS2_HUMAN relationship: location_of CCO:B0006331 ! GOLM1_HUMAN relationship: location_of CCO:B0006334 ! AMRP_HUMAN relationship: location_of CCO:B0006346 ! SCN5A_HUMAN relationship: location_of CCO:B0006350 ! VAMP8_HUMAN relationship: location_of CCO:B0010381 ! 4F2_HUMAN-Phosphothreonine5 relationship: location_of CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: location_of CCO:B0010450 ! ACV1B_HUMAN-Phosphotyrosine380 relationship: location_of CCO:B0010451 ! ADA15_HUMAN-Phosphotyrosine715 relationship: location_of CCO:B0010454 ! ADA17_HUMAN-Phosphoserine382 relationship: location_of CCO:B0010459 ! ADAM9_HUMAN-Phosphothreonine761 relationship: location_of CCO:B0010462 ! ADT2_HUMAN-Phosphoserine42 relationship: location_of CCO:B0010637 ! AT1A1_HUMAN-Phosphothreonine219 relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0010814 ! BMR1A_HUMAN-Phosphoserine220 relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0011011 ! CCPG1_HUMAN-Phosphothreonine99 relationship: location_of CCO:B0011014 ! CD28_HUMAN-Phosphotyrosine191 relationship: location_of CCO:B0011050 ! CD45_HUMAN-Phosphoserine1003 relationship: location_of CCO:B0011337 ! COX6C_HUMAN-N6-acetyllysine60 relationship: location_of CCO:B0011460 ! DDR1_HUMAN-Phosphotyrosine792 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0011722 ! EPHA2_HUMAN-Phosphotyrosine594 relationship: location_of CCO:B0011731 ! EPHB2_HUMAN-Phosphothreonine775 relationship: location_of CCO:B0011734 ! EPHB4_HUMAN-Phosphotyrosine590 relationship: location_of CCO:B0011879 ! FGFR2_HUMAN-Phosphotyrosine657 relationship: location_of CCO:B0012178 ! HECAM_HUMAN-Phosphoserine318 relationship: location_of CCO:B0012337 ! IGF1R_HUMAN-Phosphotyrosine1161 relationship: location_of CCO:B0012420 ! INSR_HUMAN-Phosphotyrosine999 relationship: location_of CCO:B0012697 ! LEPR_HUMAN-Phosphotyrosine1141 relationship: location_of CCO:B0012714 ! M2OM_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0012916 ! MET_HUMAN-Phosphotyrosine1356 relationship: location_of CCO:B0012980 ! MPCP_HUMAN-N6-acetyllysine99 relationship: location_of CCO:B0013541 ! PKD2_HUMAN-Phosphoserine254 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0014175 ! SPG7_HUMAN-Nitrated tyrosine505 relationship: location_of CCO:B0014200 ! SPTC2_HUMAN-Phosphotyrosine387 relationship: location_of CCO:B0014218 ! SSRA_HUMAN-Phosphoserine268 relationship: location_of CCO:B0014349 ! TGFR2_HUMAN-Phosphoserine548 relationship: location_of CCO:B0014576 ! UFO_HUMAN-Phosphotyrosine696 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0014603 ! VDAC2_HUMAN-Phosphoserine115 relationship: location_of CCO:B0014607 ! VDAC3_HUMAN-N6-acetyllysine61 relationship: location_of CCO:B0014615 ! VGFR1_HUMAN-Phosphotyrosine1213 relationship: location_of CCO:B0014946 ! EPHAA_HUMAN relationship: location_of CCO:B0014947 ! Q6UWM0_HUMAN relationship: location_of CCO:B0014952 ! Q6P4R6_HUMAN relationship: location_of CCO:B0014956 ! Q96L35_HUMAN relationship: location_of CCO:B0014957 ! EPHA8_HUMAN relationship: location_of CCO:B0014960 ! Q8N3Z2_HUMAN relationship: location_of CCO:B0014962 ! A8CDT5_HUMAN relationship: location_of CCO:B0014963 ! Q8IUX6_HUMAN relationship: location_of CCO:B0015065 ! CRTAM_HUMAN relationship: location_of CCO:B0015122 ! GLR_HUMAN relationship: location_of CCO:B0015123 ! GLP1R_HUMAN relationship: location_of CCO:B0015124 ! GIPR_HUMAN relationship: location_of CCO:B0015126 ! Q8NHB4_HUMAN relationship: location_of CCO:B0015134 ! GLP2R_HUMAN relationship: location_of CCO:B0015136 ! SCTR_HUMAN relationship: location_of CCO:B0015673 ! CHL1_HUMAN relationship: location_of CCO:B0015778 ! PILRB_HUMAN relationship: location_of CCO:B0015779 ! PILRA_HUMAN relationship: location_of CCO:B0016067 ! Q4G0Q6_HUMAN relationship: location_of CCO:B0016073 ! Q6P5R4_HUMAN relationship: location_of CCO:B0016682 ! GUC2D_HUMAN relationship: location_of CCO:B0016684 ! GUC2F_HUMAN relationship: location_of CCO:B0016685 ! GUC2C_HUMAN relationship: location_of CCO:B0016974 ! PK2L1_HUMAN relationship: location_of CCO:B0016983 ! Q8NH25_HUMAN relationship: location_of CCO:B0016986 ! P2RY8_HUMAN relationship: location_of CCO:B0017344 ! RET_HUMAN relationship: location_of CCO:B0017773 ! T2R40_HUMAN relationship: location_of CCO:B0017820 ! NOTC3_HUMAN relationship: location_of CCO:B0018187 ! Q5JWU1_HUMAN relationship: location_of CCO:B0018438 ! CCRL1_HUMAN relationship: location_of CCO:B0018485 ! CLTR2_HUMAN relationship: location_of CCO:B0018486 ! CLTR1_HUMAN relationship: location_of CCO:B0018655 ! RYK_HUMAN relationship: location_of CCO:B0018660 ! Q15516_HUMAN relationship: location_of CCO:B0018695 ! EDNRA_HUMAN relationship: location_of CCO:B0018697 ! EDNRB_HUMAN relationship: location_of CCO:B0018951 ! ATF6A_HUMAN relationship: location_of CCO:B0019141 ! ASGR1_HUMAN relationship: location_of CCO:B0019143 ! ASGR2_HUMAN relationship: location_of CCO:B0019513 ! TAOK2_HUMAN relationship: location_of CCO:B0019541 ! TMPS6_HUMAN relationship: location_of CCO:B0019877 ! Q7KZS6_HUMAN relationship: location_of CCO:B0020113 ! FBCD1_HUMAN relationship: location_of CCO:B0020193 ! SL9A2_HUMAN relationship: location_of CCO:B0020366 ! ACVL1_HUMAN relationship: location_of CCO:B0020368 ! ACV1C_HUMAN relationship: location_of CCO:B0020371 ! BMR1B_HUMAN relationship: location_of CCO:B0020481 ! RET1G_HUMAN relationship: location_of CCO:B0020605 ! GRIK3_HUMAN relationship: location_of CCO:B0020611 ! GRIK2_HUMAN relationship: location_of CCO:B0020614 ! GRIK1_HUMAN relationship: location_of CCO:B0020617 ! GRIK4_HUMAN relationship: location_of CCO:B0020623 ! GRIA4_HUMAN relationship: location_of CCO:B0020873 ! Q6ZTM6_HUMAN relationship: location_of CCO:B0020874 ! ADCY2_HUMAN relationship: location_of CCO:B0020879 ! ADCY7_HUMAN relationship: location_of CCO:B0020880 ! ADCY4_HUMAN relationship: location_of CCO:B0021202 ! A2A3C6_HUMAN relationship: location_of CCO:B0021203 ! A2A3C1_HUMAN relationship: location_of CCO:B0021206 ! A2A3C4_HUMAN relationship: location_of CCO:B0021208 ! A2A3C2_HUMAN relationship: location_of CCO:B0021209 ! A2A3C3_HUMAN relationship: location_of CCO:B0021210 ! BAI2_HUMAN relationship: location_of CCO:B0021417 ! CALRL_HUMAN relationship: location_of CCO:B0021419 ! A4D1G6_HUMAN relationship: location_of CCO:B0021450 ! ADR2_HUMAN relationship: location_of CCO:B0021461 ! ADR1_HUMAN relationship: location_of CCO:B0021671 ! HBEGF_HUMAN relationship: location_of CCO:B0021887 ! I17RB_HUMAN relationship: location_of CCO:B0022069 ! Q5VZI8_HUMAN relationship: location_of CCO:B0022071 ! TLR4_HUMAN relationship: location_of CCO:B0022719 ! Q6IF88_HUMAN relationship: location_of CCO:B0022721 ! OR5K3_HUMAN relationship: location_of CCO:B0022723 ! OR5K1_HUMAN relationship: location_of CCO:B0022725 ! Q8NHB6_HUMAN relationship: location_of CCO:B0022726 ! O5AC2_HUMAN relationship: location_of CCO:B0022728 ! OR5H1_HUMAN relationship: location_of CCO:B0022729 ! O5H15_HUMAN relationship: location_of CCO:B0022730 ! Q6IF87_HUMAN relationship: location_of CCO:B0022731 ! OR5K2_HUMAN relationship: location_of CCO:B0022838 ! Q8NEI9_HUMAN relationship: location_of CCO:B0022839 ! Q8NHC0_HUMAN relationship: location_of CCO:B0022840 ! Q8NH98_HUMAN relationship: location_of CCO:B0022842 ! Q8NH65_HUMAN relationship: location_of CCO:B0022843 ! Q9UPJ0_HUMAN relationship: location_of CCO:B0022844 ! Q8WZ85_HUMAN relationship: location_of CCO:B0022845 ! Q8NHB5_HUMAN relationship: location_of CCO:B0022846 ! Q8NH97_HUMAN relationship: location_of CCO:B0022847 ! Q8NH99_HUMAN relationship: location_of CCO:B0022848 ! Q9P1R1_HUMAN relationship: location_of CCO:B0022849 ! Q8NH46_HUMAN relationship: location_of CCO:B0022852 ! Q8NGT4_HUMAN relationship: location_of CCO:B0022854 ! Q8NHC1_HUMAN relationship: location_of CCO:B0022856 ! Q8NGP1_HUMAN relationship: location_of CCO:B0022857 ! Q8NHB9_HUMAN relationship: location_of CCO:B0022858 ! Q8NH45_HUMAN relationship: location_of CCO:B0022861 ! O7E24_HUMAN relationship: location_of CCO:B0022862 ! Q9UDD8_HUMAN relationship: location_of CCO:B0022863 ! Q15618_HUMAN relationship: location_of CCO:B0022865 ! Q8NHA1_HUMAN relationship: location_of CCO:B0022866 ! Q8NG89_HUMAN relationship: location_of CCO:B0022870 ! Q96N54_HUMAN relationship: location_of CCO:B0022873 ! Q8NGD7_HUMAN relationship: location_of CCO:B0022899 ! GBRR2_HUMAN relationship: location_of CCO:B0022900 ! GBRG3_HUMAN relationship: location_of CCO:B0022901 ! GBRE_HUMAN relationship: location_of CCO:B0022902 ! Q8IYR7_HUMAN relationship: location_of CCO:B0022903 ! GBRT_HUMAN relationship: location_of CCO:B0022906 ! GBRG1_HUMAN relationship: location_of CCO:B0022907 ! GBRA6_HUMAN relationship: location_of CCO:B0022909 ! GBRG2_HUMAN relationship: location_of CCO:B0022911 ! GLRB_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022914 ! GBRA1_HUMAN relationship: location_of CCO:B0022915 ! GBRA5_HUMAN relationship: location_of CCO:B0022917 ! GLRA2_HUMAN relationship: location_of CCO:B0022924 ! GBRA2_HUMAN relationship: location_of CCO:B0022926 ! GBRR1_HUMAN relationship: location_of CCO:B0022931 ! GBRD_HUMAN relationship: location_of CCO:B0022933 ! GBRA3_HUMAN relationship: location_of CCO:B0022935 ! Q6PCC3_HUMAN relationship: location_of CCO:B0022999 ! PTPRK_HUMAN relationship: location_of CCO:B0023006 ! PTPRT_HUMAN relationship: location_of CCO:B0023019 ! PTPRU_HUMAN relationship: location_of CCO:B0023179 ! NPTN_HUMAN relationship: location_of CCO:B0023521 ! CD2_HUMAN relationship: location_of CCO:B0024051 ! ADEC1_HUMAN relationship: location_of CCO:B0024303 ! Q4VBB4_HUMAN relationship: location_of CCO:B0024306 ! PSYR_HUMAN relationship: location_of CCO:B0024308 ! GPR4_HUMAN relationship: location_of CCO:B0024312 ! DLL3_HUMAN relationship: location_of CCO:B0025098 ! LETM1_HUMAN relationship: location_of CCO:B0025167 ! TRPC5_HUMAN relationship: location_of CCO:B0025169 ! TRPC1_HUMAN relationship: location_of CCO:B0025184 ! IL6RB_HUMAN relationship: location_of CCO:B0025401 ! MS4A7_HUMAN relationship: location_of CCO:B0025403 ! A6NP53_HUMAN relationship: location_of CCO:B0025847 ! PTPRN_HUMAN relationship: location_of CCO:B0025951 ! LRP5_HUMAN relationship: location_of CCO:B0025967 ! LRP6_HUMAN relationship: location_of CCO:B0025995 ! Q96B13_HUMAN relationship: location_of CCO:B0026210 ! Q59FA8_HUMAN relationship: location_of CCO:B0026213 ! ITA8_HUMAN relationship: location_of CCO:B0026215 ! ITA2B_HUMAN relationship: location_of CCO:B0026216 ! Q17R67_HUMAN relationship: location_of CCO:B0026217 ! ITA5_HUMAN relationship: location_of CCO:B0026218 ! ITAV_HUMAN relationship: location_of CCO:B0026256 ! RPRM_HUMAN relationship: location_of CCO:B0026448 ! AT2C1_HUMAN relationship: location_of CCO:B0026726 ! MRGRF_HUMAN relationship: location_of CCO:B0026851 ! HERP1_HUMAN relationship: location_of CCO:B0026865 ! SORC1_HUMAN relationship: location_of CCO:B0026866 ! SORC3_HUMAN relationship: location_of CCO:B0026867 ! SORC2_HUMAN relationship: location_of CCO:B0027056 ! A8MWU7_HUMAN relationship: location_of CCO:B0027058 ! A8MX51_HUMAN relationship: location_of CCO:B0027148 ! S61A2_HUMAN relationship: location_of CCO:B0027154 ! S61A1_HUMAN relationship: location_of CCO:B0027270 ! FDFT_HUMAN relationship: location_of CCO:B0027571 ! SLIT2_HUMAN relationship: location_of CCO:B0027573 ! Q5T0V3_HUMAN relationship: location_of CCO:B0027574 ! Q5T0V2_HUMAN relationship: location_of CCO:B0027593 ! CDIPT_HUMAN relationship: location_of CCO:B0028140 ! VATL_HUMAN relationship: location_of CCO:B0028201 ! OR1D2_HUMAN relationship: location_of CCO:B0028205 ! Q6IFM2_HUMAN relationship: location_of CCO:B0028206 ! Q6IFL7_HUMAN relationship: location_of CCO:B0028290 ! JAG1_HUMAN relationship: location_of CCO:B0028291 ! DLL4_HUMAN relationship: location_of CCO:B0028292 ! DLL1_HUMAN relationship: location_of CCO:B0028758 ! SPTC1_HUMAN relationship: location_of CCO:B0029013 ! OR9I1_HUMAN relationship: location_of CCO:B0029014 ! Q6IF62_HUMAN relationship: location_of CCO:B0029015 ! OR5W2_HUMAN relationship: location_of CCO:B0029017 ! OR5B3_HUMAN relationship: location_of CCO:B0029019 ! Q8NH91_HUMAN relationship: location_of CCO:B0029022 ! OR8K5_HUMAN relationship: location_of CCO:B0029023 ! OR5L1_HUMAN relationship: location_of CCO:B0029024 ! OR5B2_HUMAN relationship: location_of CCO:B0029025 ! OR8U1_HUMAN relationship: location_of CCO:B0029027 ! A8MUX1_HUMAN relationship: location_of CCO:B0029028 ! OR5BC_HUMAN relationship: location_of CCO:B0029029 ! OR5R1_HUMAN relationship: location_of CCO:B0029030 ! OR5C1_HUMAN relationship: location_of CCO:B0029031 ! OR8G5_HUMAN relationship: location_of CCO:B0029032 ! Q6IEU2_HUMAN relationship: location_of CCO:B0029033 ! OR5J2_HUMAN relationship: location_of CCO:B0029034 ! OR8D4_HUMAN relationship: location_of CCO:B0029035 ! O5AR1_HUMAN relationship: location_of CCO:B0029036 ! Q6IFM9_HUMAN relationship: location_of CCO:B0029037 ! A8MXK6_HUMAN relationship: location_of CCO:B0029038 ! O5AS1_HUMAN relationship: location_of CCO:B0029039 ! OR5BH_HUMAN relationship: location_of CCO:B0029040 ! OR5L2_HUMAN relationship: location_of CCO:B0029064 ! Q17RW0_HUMAN relationship: location_of CCO:B0029727 ! CEAM1_HUMAN relationship: location_of CCO:B0030075 ! A8MTR7_HUMAN relationship: location_of CCO:B0030164 ! TLR1_HUMAN relationship: location_of CCO:B0030165 ! TLR10_HUMAN relationship: location_of CCO:B0030171 ! TLR2_HUMAN relationship: location_of CCO:B0030172 ! TLR6_HUMAN relationship: location_of CCO:B0030552 ! MC3R_HUMAN relationship: location_of CCO:B0030561 ! MSHR_HUMAN relationship: location_of CCO:B0030569 ! MC5R_HUMAN relationship: location_of CCO:B0030574 ! MC4R_HUMAN relationship: location_of CCO:B0030577 ! ACTHR_HUMAN relationship: location_of CCO:B0030651 ! AMHR2_HUMAN relationship: location_of CCO:B0030754 ! VAMP3_HUMAN-Phosphoserine58 relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: location_of CCO:B0030995 ! IRK2_HUMAN relationship: location_of CCO:B0031296 ! AT1B1_HUMAN-Phosphotyrosine101 relationship: location_of CCO:B0031317 ! FGFR3_HUMAN-Phosphotyrosine647 relationship: location_of CCO:B0031607 ! TA2R5_HUMAN relationship: location_of CCO:B0032298 ! I17RA_HUMAN relationship: location_of CCO:B0032345 ! Q5Y190_HUMAN relationship: location_of CCO:B0032349 ! CELR2_HUMAN relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0032799 ! ACHB3_HUMAN relationship: location_of CCO:B0032804 ! ACHA3_HUMAN relationship: location_of CCO:B0032806 ! ACHA5_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0032809 ! ACHA2_HUMAN relationship: location_of CCO:B0033120 ! ITB5_HUMAN relationship: location_of CCO:B0033125 ! ITB8_HUMAN relationship: location_of CCO:B0033128 ! Q59FN1_HUMAN relationship: location_of CCO:B0033132 ! Q59H50_HUMAN relationship: location_of CCO:B0033133 ! ITB6_HUMAN relationship: location_of CCO:B0033134 ! A8MYE6_HUMAN relationship: location_of CCO:B0033136 ! Q8WUM6_HUMAN relationship: location_of CCO:B0033137 ! ITB7_HUMAN relationship: location_of CCO:B0033141 ! ITB3_HUMAN relationship: location_of CCO:B0033252 ! OPSX_HUMAN relationship: location_of CCO:B0033253 ! A6NEB4_HUMAN relationship: location_of CCO:B0033254 ! OPN4_HUMAN relationship: location_of CCO:B0033335 ! Q6IFC7_HUMAN relationship: location_of CCO:B0033337 ! A8MTX1_HUMAN relationship: location_of CCO:B0033338 ! OR5T1_HUMAN relationship: location_of CCO:B0033339 ! A8MW53_HUMAN relationship: location_of CCO:B0033340 ! O5AK3_HUMAN relationship: location_of CCO:B0033341 ! OR5K4_HUMAN relationship: location_of CCO:B0033342 ! A8MWJ9_HUMAN relationship: location_of CCO:B0033343 ! Q6IFC8_HUMAN relationship: location_of CCO:B0033344 ! OR9Q2_HUMAN relationship: location_of CCO:B0033345 ! A8MXY9_HUMAN relationship: location_of CCO:B0033346 ! OR5I1_HUMAN relationship: location_of CCO:B0033347 ! O5AC1_HUMAN relationship: location_of CCO:B0033348 ! A8MVK2_HUMAN relationship: location_of CCO:B0033349 ! O5H14_HUMAN relationship: location_of CCO:B0033351 ! Q8IXE7_HUMAN relationship: location_of CCO:B0033365 ! LASS4_HUMAN relationship: location_of CCO:B0033366 ! LASS3_HUMAN relationship: location_of CCO:B0033369 ! LASS6_HUMAN relationship: location_of CCO:B0033374 ! Q5SZE3_HUMAN relationship: location_of CCO:B0033376 ! Q5SZE4_HUMAN relationship: location_of CCO:B0033382 ! Q32M63_HUMAN relationship: location_of CCO:B0033383 ! A8K4M4_HUMAN relationship: location_of CCO:B0033402 ! Q14CE0_HUMAN relationship: location_of CCO:B0033403 ! Q6F3F5_HUMAN relationship: location_of CCO:B0033404 ! Q6F3F6_HUMAN relationship: location_of CCO:B0033406 ! A2A2J1_HUMAN relationship: location_of CCO:B0033407 ! A2A2J2_HUMAN relationship: location_of CCO:B0033410 ! A9Z1X2_HUMAN relationship: location_of CCO:B0033411 ! Q6F3F8_HUMAN relationship: location_of CCO:B0033412 ! GP112_HUMAN relationship: location_of CCO:B0033414 ! Q499H0_HUMAN relationship: location_of CCO:B0033415 ! Q5EGP2_HUMAN relationship: location_of CCO:B0033418 ! GPR64_HUMAN relationship: location_of CCO:B0033419 ! Q6F3F7_HUMAN relationship: location_of CCO:B0033477 ! LRP8_HUMAN relationship: location_of CCO:B0034023 ! S26A5_HUMAN relationship: location_of CCO:B0034126 ! RARG_HUMAN relationship: location_of CCO:B0034159 ! AQP1_HUMAN relationship: location_of CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0034526 ! AFG32_HUMAN-N6-acetyllysine308 relationship: location_of CCO:B0034532 ! AMD_HUMAN-Phosphoserine955 relationship: location_of CCO:B0034546 ! ANPRA_HUMAN-Phosphoserine534 relationship: location_of CCO:B0034552 ! ANPRB_HUMAN-Phosphoserine518 relationship: location_of CCO:B0034583 ! B2L13_HUMAN-Phosphoserine420 relationship: location_of CCO:B0034728 ! EPHA1_HUMAN-Phosphoserine34 relationship: location_of CCO:B0034734 ! EPHA3_HUMAN-Phosphotyrosine596 relationship: location_of CCO:B0034739 ! EPHA4_HUMAN-Phosphotyrosine602 relationship: location_of CCO:B0034742 ! EPHA5_HUMAN-Phosphotyrosine650 relationship: location_of CCO:B0034746 ! EPHA6_HUMAN-Phosphotyrosine605 relationship: location_of CCO:B0034753 ! EPHA7_HUMAN-Phosphotyrosine940 relationship: location_of CCO:B0034756 ! EPHB1_HUMAN-Phosphotyrosine594 relationship: location_of CCO:B0034788 ! FCERB_HUMAN-Phosphotyrosine229 relationship: location_of CCO:B0034813 ! FPR1_HUMAN-Phosphothreonine339 relationship: location_of CCO:B0034864 ! I12R2_HUMAN-Phosphotyrosine800 relationship: location_of CCO:B0034872 ! IL3RB_HUMAN-Phosphotyrosine766 relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0034889 ! ITB2_HUMAN-Phosphothreonine759 relationship: location_of CCO:B0034894 ! ITB4_HUMAN-Phosphoserine1084 relationship: location_of CCO:B0035082 ! L1CAM_HUMAN-Phosphoserine1248 relationship: location_of CCO:B0035088 ! LASS2_HUMAN-Phosphoserine341 relationship: location_of CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: location_of CCO:B0035123 ! LRP1_HUMAN-Phosphotyrosine4507 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035292 ! NMDE4_HUMAN-Phosphoserine1326 relationship: location_of CCO:B0035307 ! NRCAM_HUMAN-Phosphoserine427 relationship: location_of CCO:B0035358 ! PECA1_HUMAN-Phosphotyrosine713 relationship: location_of CCO:B0035368 ! PGFRB_HUMAN-Phosphotyrosine857 relationship: location_of CCO:B0035817 ! TRPC4_HUMAN-Phosphoserine195 relationship: location_of CCO:B0035937 ! S26A8_HUMAN relationship: location_of CCO:B0035985 ! ACVR1_HUMAN-Phosphoserine501 relationship: location_of CCO:B0035998 ! DCC_HUMAN-Phosphothreonine1074 relationship: location_of CCO:B0036594 ! NKG2C_HUMAN relationship: location_of CCO:B0036600 ! NKG2A_HUMAN relationship: location_of CCO:B0036631 ! LRRN2_HUMAN relationship: location_of CCO:B0037083 ! RXFP2_HUMAN relationship: location_of CCO:B0037085 ! RXFP1_HUMAN relationship: location_of CCO:B0037087 ! Q3KU23_HUMAN relationship: location_of CCO:B0037130 ! DJB12_HUMAN relationship: location_of CCO:B0037223 ! A8MSY3_HUMAN relationship: location_of CCO:B0037226 ! O00325_HUMAN relationship: location_of CCO:B0037228 ! Q5CZ60_HUMAN relationship: location_of CCO:B0037229 ! PE2R3_HUMAN relationship: location_of CCO:B0037230 ! Q5CZ59_HUMAN relationship: location_of CCO:B0037231 ! Q5CZ62_HUMAN relationship: location_of CCO:B0037235 ! A8K3L9_HUMAN relationship: location_of CCO:B0037236 ! Q147X8_HUMAN relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0038260 ! 5HT2C_HUMAN relationship: location_of CCO:B0038261 ! Q7Z5R9_HUMAN relationship: location_of CCO:B0038262 ! HRH2_HUMAN relationship: location_of CCO:B0038263 ! ADA1B_HUMAN relationship: location_of CCO:B0038265 ! ADA1D_HUMAN relationship: location_of CCO:B0038266 ! 5HT1D_HUMAN relationship: location_of CCO:B0038267 ! ADA2B_HUMAN relationship: location_of CCO:B0038563 ! ADA11_HUMAN relationship: location_of CCO:B0038590 ! Q6IFJ9_HUMAN relationship: location_of CCO:B0038591 ! Q8NG79_HUMAN relationship: location_of CCO:B0038592 ! OR6M1_HUMAN relationship: location_of CCO:B0038594 ! A6NJJ1_HUMAN relationship: location_of CCO:B0038734 ! DPP4_HUMAN relationship: location_of CCO:B0038854 ! FZD5_HUMAN relationship: location_of CCO:B0038855 ! FZD1_HUMAN relationship: location_of CCO:B0038856 ! FZD7_HUMAN relationship: location_of CCO:B0038857 ! FZD2_HUMAN relationship: location_of CCO:B0038861 ! FZD9_HUMAN relationship: location_of CCO:B0038863 ! FZD8_HUMAN relationship: location_of CCO:B0038865 ! FZD10_HUMAN relationship: location_of CCO:B0038878 ! CSF1_HUMAN relationship: location_of CCO:B0038926 ! TRPV4_HUMAN relationship: location_of CCO:B0038991 ! CSTN1_HUMAN relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0039298 ! ADA1A_HUMAN-Phosphoserine215 relationship: location_of CCO:B0039301 ! ADA22_HUMAN-Phosphoserine834 relationship: location_of CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: location_of CCO:B0039581 ! PGFRA_HUMAN-Phosphotyrosine720 relationship: location_of CCO:B0039588 ! PLS1_HUMAN-Phosphotyrosine69 relationship: location_of CCO:B0039642 ! RRBP1_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0039677 ! TGFR1_HUMAN-Phosphoserine191 relationship: location_of CCO:B0039687 ! TRPV1_HUMAN-Phosphoserine775 relationship: location_of CCO:B0039914 ! TR13B_HUMAN relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0040688 ! RPN1_HUMAN relationship: location_of CCO:B0041279 ! TM90B_HUMAN relationship: location_of CCO:B0041921 ! B0UXY8_HUMAN relationship: location_of CCO:B0041924 ! Q8NHA5_HUMAN relationship: location_of CCO:B0041925 ! B0UXY7_HUMAN relationship: location_of CCO:B0041927 ! A6NNW8_HUMAN relationship: location_of CCO:B0042221 ! A8MT20_HUMAN relationship: location_of CCO:B0042222 ! GRM3_HUMAN relationship: location_of CCO:B0042225 ! GRM4_HUMAN relationship: location_of CCO:B0042226 ! Q8N0Z0_HUMAN relationship: location_of CCO:B0042227 ! GRM7_HUMAN relationship: location_of CCO:B0042228 ! A4D0Y3_HUMAN relationship: location_of CCO:B0042229 ! Q8NHA9_HUMAN relationship: location_of CCO:B0042230 ! GRM5_HUMAN relationship: location_of CCO:B0042232 ! Q59GK5_HUMAN relationship: location_of CCO:B0042233 ! Q99997_HUMAN relationship: location_of CCO:B0042237 ! Q86YG3_HUMAN relationship: location_of CCO:B0042238 ! Q6J164_HUMAN relationship: location_of CCO:B0042239 ! GRM2_HUMAN relationship: location_of CCO:B0042241 ! GRM8_HUMAN relationship: location_of CCO:B0042244 ! GRM6_HUMAN relationship: location_of CCO:B0042246 ! A8K1R9_HUMAN relationship: location_of CCO:B0042247 ! Q2PNZ6_HUMAN relationship: location_of CCO:B0042251 ! Q6ZMQ2_HUMAN relationship: location_of CCO:B0042255 ! Q59HC2_HUMAN relationship: location_of CCO:B0042293 ! ACHG_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0042813 ! IL2RB_HUMAN relationship: location_of CCO:B0042830 ! FCERA_HUMAN relationship: location_of CCO:B0043276 ! FLNB_HUMAN-Phosphoserine983 relationship: location_of CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 relationship: location_of CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: location_of CCO:B0043364 ! RTN3_HUMAN-Phosphoserine735 relationship: location_of CCO:B0043374 ! RTN4_HUMAN-Phosphoserine863 relationship: location_of CCO:B0043430 ! RNF5_HUMAN relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0043817 ! NGX6_HUMAN relationship: location_of CCO:B0043833 ! SC5A8_HUMAN relationship: location_of CCO:B0043866 ! LPAR2_HUMAN relationship: location_of CCO:B0043867 ! LPAR4_HUMAN relationship: location_of CCO:B0048252 ! EFNB1_HUMAN-Phosphotyrosine317 relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0048304 ! K1549_HUMAN-Phosphoserine1319 relationship: location_of CCO:B0048923 ! B1AKC9_HUMAN relationship: location_of CCO:B0048954 ! IL31R_HUMAN relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0049157 ! PAR4_HUMAN relationship: location_of CCO:B0049159 ! Q7Z3W3_HUMAN relationship: location_of CCO:B0049161 ! PAR2_HUMAN relationship: location_of CCO:B0049421 ! KCNQ1_HUMAN relationship: location_of CCO:B0049445 ! A6NEW7_HUMAN relationship: location_of CCO:B0049448 ! Q53TQ2_HUMAN relationship: location_of CCO:B0049452 ! NK2R_HUMAN relationship: location_of CCO:B0049455 ! NK3R_HUMAN relationship: location_of CCO:B0049457 ! NK1R_HUMAN relationship: location_of CCO:B0049552 ! A9YLN5_HUMAN relationship: location_of CCO:B0049553 ! A9YLN4_HUMAN relationship: location_of CCO:B0049556 ! Q5H8Y1_HUMAN relationship: location_of CCO:B0049557 ! A9YLN6_HUMAN relationship: location_of CCO:B0049558 ! HG2A_HUMAN relationship: location_of CCO:B0049576 ! NRG1_HUMAN relationship: location_of CCO:B0049698 ! CLD7_HUMAN relationship: location_of CCO:B0049806 ! OR8H1_HUMAN relationship: location_of CCO:B0049809 ! A8MYY4_HUMAN relationship: location_of CCO:B0049812 ! A8MYM5_HUMAN relationship: location_of CCO:B0049813 ! OR8B4_HUMAN relationship: location_of CCO:B0049814 ! OR8H3_HUMAN relationship: location_of CCO:B0049816 ! OR8H2_HUMAN relationship: location_of CCO:B0049817 ! OR5MB_HUMAN relationship: location_of CCO:B0049915 ! RAMP3_HUMAN relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0050006 ! CD72_HUMAN relationship: location_of CCO:B0050188 ! Q4VAK1_HUMAN relationship: location_of CCO:B0050189 ! ITAM_HUMAN relationship: location_of CCO:B0050190 ! ITAD_HUMAN relationship: location_of CCO:B0050191 ! ITA11_HUMAN relationship: location_of CCO:B0050192 ! ITAX_HUMAN relationship: location_of CCO:B0050193 ! Q59H14_HUMAN relationship: location_of CCO:B0050195 ! Q8TES5_HUMAN relationship: location_of CCO:B0050196 ! ITA2_HUMAN relationship: location_of CCO:B0050197 ! A8MPT3_HUMAN relationship: location_of CCO:B0050198 ! A8MTX2_HUMAN relationship: location_of CCO:B0050199 ! Q96HB1_HUMAN relationship: location_of CCO:B0050200 ! A8MZ95_HUMAN relationship: location_of CCO:B0050202 ! ITAL_HUMAN relationship: location_of CCO:B0050612 ! NCKP1_HUMAN relationship: location_of CCO:B0050753 ! OPRD_HUMAN relationship: location_of CCO:B0050755 ! SSR2_HUMAN relationship: location_of CCO:B0050756 ! Q9H573_HUMAN relationship: location_of CCO:B0050758 ! OPRK_HUMAN relationship: location_of CCO:B0050760 ! A6NL10_HUMAN relationship: location_of CCO:B0050761 ! Q8IXB0_HUMAN relationship: location_of CCO:B0050764 ! NPBW2_HUMAN relationship: location_of CCO:B0050772 ! Q8IWW3_HUMAN relationship: location_of CCO:B0050781 ! OPRX_HUMAN relationship: location_of CCO:B0050782 ! NPBW1_HUMAN relationship: location_of CCO:B0050784 ! Q8IWP3_HUMAN relationship: location_of CCO:B0050788 ! SSR1_HUMAN relationship: location_of CCO:B0050791 ! Q5TBX0_HUMAN relationship: location_of CCO:B0050792 ! Q8IWW4_HUMAN relationship: location_of CCO:B0050793 ! SSR4_HUMAN relationship: location_of CCO:B0050794 ! SSR3_HUMAN relationship: location_of CCO:B0050997 ! MFN2_HUMAN relationship: location_of CCO:B0051232 ! CLPT1_HUMAN relationship: location_of CCO:B0051475 ! MOT3_HUMAN relationship: location_of CCO:B0051877 ! OR8D2_HUMAN relationship: location_of CCO:B0051880 ! OR8G1_HUMAN relationship: location_of CCO:B0051882 ! OR8G2_HUMAN relationship: location_of CCO:B0051883 ! OR8U9_HUMAN relationship: location_of CCO:B0051887 ! O5AK2_HUMAN relationship: location_of CCO:B0051892 ! OR8U8_HUMAN relationship: location_of CCO:B0051893 ! O5AP2_HUMAN relationship: location_of CCO:B0052320 ! CD40L_HUMAN-Phosphothreonine4 relationship: location_of CCO:B0052624 ! PGRC1_HUMAN-Phosphoserine181 relationship: location_of CCO:B0052705 ! ROS_HUMAN-Phosphotyrosine2114 relationship: location_of CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: location_of CCO:B0052794 ! SSR5_HUMAN-Phosphoserine325 relationship: location_of CCO:B0052851 ! TMCC2_HUMAN-Phosphoserine481 relationship: location_of CCO:B0053696 ! A0A502_HUMAN relationship: location_of CCO:B0053703 ! A0PJU7_HUMAN relationship: location_of CCO:B0053711 ! A1L156_HUMAN relationship: location_of CCO:B0053724 ! A2BDZ0_HUMAN relationship: location_of CCO:B0053725 ! A2BDZ2_HUMAN relationship: location_of CCO:B0053726 ! A2BEC2_HUMAN relationship: location_of CCO:B0053727 ! A2BF33_HUMAN relationship: location_of CCO:B0053728 ! A2BF34_HUMAN relationship: location_of CCO:B0053742 ! OR2M5_HUMAN relationship: location_of CCO:B0053758 ! A4D2G2_HUMAN relationship: location_of CCO:B0053759 ! O2A25_HUMAN relationship: location_of CCO:B0053771 ! A4QMS5_HUMAN relationship: location_of CCO:B0053783 ! A6NC31_HUMAN relationship: location_of CCO:B0053784 ! A6NC89_HUMAN relationship: location_of CCO:B0053786 ! O6C74_HUMAN relationship: location_of CCO:B0053788 ! O14I1_HUMAN relationship: location_of CCO:B0053793 ! O6C68_HUMAN relationship: location_of CCO:B0053797 ! A6NDW2_HUMAN relationship: location_of CCO:B0053800 ! A6NE11_HUMAN relationship: location_of CCO:B0053805 ! A6NE96_HUMAN relationship: location_of CCO:B0053807 ! A6NEF2_HUMAN relationship: location_of CCO:B0053813 ! A6NF12_HUMAN relationship: location_of CCO:B0053816 ! OR6C6_HUMAN relationship: location_of CCO:B0053817 ! OR2W5_HUMAN relationship: location_of CCO:B0053818 ! A6NFD6_HUMAN relationship: location_of CCO:B0053824 ! A6NFR0_HUMAN relationship: location_of CCO:B0053827 ! A6NG39_HUMAN relationship: location_of CCO:B0053834 ! A6NGT9_HUMAN relationship: location_of CCO:B0053835 ! O51F1_HUMAN relationship: location_of CCO:B0053836 ! OR2T8_HUMAN relationship: location_of CCO:B0053839 ! A6NH54_HUMAN relationship: location_of CCO:B0053842 ! A6NH69_HUMAN relationship: location_of CCO:B0053845 ! O4C46_HUMAN relationship: location_of CCO:B0053849 ! A6NHK6_HUMAN relationship: location_of CCO:B0053861 ! A6NIH4_HUMAN relationship: location_of CCO:B0053862 ! O6C70_HUMAN relationship: location_of CCO:B0053863 ! A6NIQ0_HUMAN relationship: location_of CCO:B0053866 ! A6NJ05_HUMAN relationship: location_of CCO:B0053875 ! O6C65_HUMAN relationship: location_of CCO:B0053886 ! A6NKK7_HUMAN relationship: location_of CCO:B0053887 ! A6NKM1_HUMAN relationship: location_of CCO:B0053890 ! O6C75_HUMAN relationship: location_of CCO:B0053892 ! OR5BL_HUMAN relationship: location_of CCO:B0053893 ! A6NL96_HUMAN relationship: location_of CCO:B0053895 ! EA3L2_HUMAN relationship: location_of CCO:B0053902 ! O2AG2_HUMAN relationship: location_of CCO:B0053904 ! O6C76_HUMAN relationship: location_of CCO:B0053908 ! O52A4_HUMAN relationship: location_of CCO:B0053909 ! A6NMV7_HUMAN relationship: location_of CCO:B0053910 ! O4C45_HUMAN relationship: location_of CCO:B0053911 ! A6NN09_HUMAN relationship: location_of CCO:B0053914 ! O2AT4_HUMAN relationship: location_of CCO:B0053917 ! A6NNL3_HUMAN relationship: location_of CCO:B0053921 ! A6NNY4_HUMAN relationship: location_of CCO:B0053939 ! A6QRH2_HUMAN relationship: location_of CCO:B0053948 ! A7L9S6_HUMAN relationship: location_of CCO:B0053957 ! A8K2J1_HUMAN relationship: location_of CCO:B0053959 ! A8K2Y6_HUMAN relationship: location_of CCO:B0053960 ! A8K305_HUMAN relationship: location_of CCO:B0053966 ! A8K4E4_HUMAN relationship: location_of CCO:B0053973 ! A8K6W1_HUMAN relationship: location_of CCO:B0053978 ! A8K8D4_HUMAN relationship: location_of CCO:B0054001 ! A8MQV3_HUMAN relationship: location_of CCO:B0054018 ! A8MSZ9_HUMAN relationship: location_of CCO:B0054022 ! A8MT74_HUMAN relationship: location_of CCO:B0054024 ! A8MTE1_HUMAN relationship: location_of CCO:B0054032 ! A8MTP8_HUMAN relationship: location_of CCO:B0054037 ! A8MU07_HUMAN relationship: location_of CCO:B0054039 ! A8MUF8_HUMAN relationship: location_of CCO:B0054042 ! A8MUM9_HUMAN relationship: location_of CCO:B0054043 ! A8MUR1_HUMAN relationship: location_of CCO:B0054045 ! A8MUS4_HUMAN relationship: location_of CCO:B0054049 ! A8MUW4_HUMAN relationship: location_of CCO:B0054050 ! A8MUY8_HUMAN relationship: location_of CCO:B0054052 ! A8MV06_HUMAN relationship: location_of CCO:B0054058 ! A8MVF0_HUMAN relationship: location_of CCO:B0054061 ! A8MVM5_HUMAN relationship: location_of CCO:B0054066 ! A8MVV5_HUMAN relationship: location_of CCO:B0054073 ! A8MW54_HUMAN relationship: location_of CCO:B0054079 ! A8MWG5_HUMAN relationship: location_of CCO:B0054080 ! A8MWI1_HUMAN relationship: location_of CCO:B0054086 ! A8MX01_HUMAN relationship: location_of CCO:B0054091 ! A8MX59_HUMAN relationship: location_of CCO:B0054093 ! A8MX88_HUMAN relationship: location_of CCO:B0054094 ! A8MXA6_HUMAN relationship: location_of CCO:B0054095 ! A8MXE9_HUMAN relationship: location_of CCO:B0054097 ! A8MXI2_HUMAN relationship: location_of CCO:B0054098 ! A8MXI6_HUMAN relationship: location_of CCO:B0054100 ! A8MXL5_HUMAN relationship: location_of CCO:B0054104 ! A8MXU4_HUMAN relationship: location_of CCO:B0054108 ! A8MXZ2_HUMAN relationship: location_of CCO:B0054109 ! A8MXZ4_HUMAN relationship: location_of CCO:B0054111 ! A8MY27_HUMAN relationship: location_of CCO:B0054116 ! A8MY83_HUMAN relationship: location_of CCO:B0054135 ! A8MZ16_HUMAN relationship: location_of CCO:B0054136 ! A8MZ46_HUMAN relationship: location_of CCO:B0054142 ! A8MZG7_HUMAN relationship: location_of CCO:B0054144 ! A8MZL3_HUMAN relationship: location_of CCO:B0054155 ! A9UJY7_HUMAN relationship: location_of CCO:B0054161 ! B0AZS9_HUMAN relationship: location_of CCO:B0054162 ! B0AZW0_HUMAN relationship: location_of CCO:B0054185 ! B0S882_HUMAN relationship: location_of CCO:B0054186 ! B0UY34_HUMAN relationship: location_of CCO:B0054189 ! B0V1T2_HUMAN relationship: location_of CCO:B0054190 ! B0V1T3_HUMAN relationship: location_of CCO:B0054191 ! B0V1X5_HUMAN relationship: location_of CCO:B0054192 ! B0V386_HUMAN relationship: location_of CCO:B0054198 ! B0ZBD2_HUMAN relationship: location_of CCO:B0054199 ! B0ZBD3_HUMAN relationship: location_of CCO:B0054200 ! B0ZBD8_HUMAN relationship: location_of CCO:B0054224 ! B1AK19_HUMAN relationship: location_of CCO:B0054241 ! B1ALU1_HUMAN relationship: location_of CCO:B0054242 ! B1ALU2_HUMAN relationship: location_of CCO:B0054243 ! B1ALU3_HUMAN relationship: location_of CCO:B0054244 ! B1ALU4_HUMAN relationship: location_of CCO:B0054245 ! B1ALU5_HUMAN relationship: location_of CCO:B0054246 ! B1ALU6_HUMAN relationship: location_of CCO:B0054251 ! B1AMA2_HUMAN relationship: location_of CCO:B0054256 ! B1AMW4_HUMAN relationship: location_of CCO:B0054259 ! B1AN12_HUMAN relationship: location_of CCO:B0054267 ! B1AP22_HUMAN relationship: location_of CCO:B0054268 ! B1AP63_HUMAN relationship: location_of CCO:B0054278 ! B1AWB3_HUMAN relationship: location_of CCO:B0054279 ! B1AWB4_HUMAN relationship: location_of CCO:B0054280 ! B1AWB6_HUMAN relationship: location_of CCO:B0054281 ! B1AWB7_HUMAN relationship: location_of CCO:B0054282 ! B1B0A5_HUMAN relationship: location_of CCO:B0054283 ! B1B1F0_HUMAN relationship: location_of CCO:B0054291 ! GPR25_HUMAN relationship: location_of CCO:B0054302 ! SIRB1_HUMAN relationship: location_of CCO:B0054306 ! GPR31_HUMAN relationship: location_of CCO:B0054316 ! P2Y10_HUMAN relationship: location_of CCO:B0054318 ! CCRL2_HUMAN relationship: location_of CCO:B0054322 ! LST1_HUMAN relationship: location_of CCO:B0054333 ! CXCR6_HUMAN relationship: location_of CCO:B0054335 ! CCBP2_HUMAN relationship: location_of CCO:B0054336 ! PODXL_HUMAN relationship: location_of CCO:B0054344 ! LPP1_HUMAN relationship: location_of CCO:B0054346 ! NRG2_HUMAN relationship: location_of CCO:B0054348 ! BAI1_HUMAN relationship: location_of CCO:B0054353 ! OR7AH_HUMAN relationship: location_of CCO:B0054360 ! GP171_HUMAN relationship: location_of CCO:B0054364 ! ADA10_HUMAN relationship: location_of CCO:B0054365 ! EI24_HUMAN relationship: location_of CCO:B0054367 ! PTGES_HUMAN relationship: location_of CCO:B0054368 ! O14694_HUMAN relationship: location_of CCO:B0054373 ! TR10B_HUMAN relationship: location_of CCO:B0054375 ! TNF11_HUMAN relationship: location_of CCO:B0054378 ! TAAR5_HUMAN relationship: location_of CCO:B0054383 ! FFAR3_HUMAN relationship: location_of CCO:B0054386 ! MGST3_HUMAN relationship: location_of CCO:B0054417 ! GP182_HUMAN relationship: location_of CCO:B0054432 ! GPR37_HUMAN relationship: location_of CCO:B0054440 ! INSI1_HUMAN relationship: location_of CCO:B0054444 ! GPR42_HUMAN relationship: location_of CCO:B0054448 ! FFAR2_HUMAN relationship: location_of CCO:B0054451 ! PLXB1_HUMAN relationship: location_of CCO:B0054458 ! O43192_HUMAN relationship: location_of CCO:B0054459 ! MTLR_HUMAN relationship: location_of CCO:B0054460 ! GPR39_HUMAN relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0054484 ! TNF12_HUMAN relationship: location_of CCO:B0054485 ! AT8B1_HUMAN relationship: location_of CCO:B0054490 ! TNF14_HUMAN relationship: location_of CCO:B0054498 ! GALR2_HUMAN relationship: location_of CCO:B0054503 ! OX2R_HUMAN relationship: location_of CCO:B0054505 ! O43627_HUMAN relationship: location_of CCO:B0054508 ! TSN6_HUMAN relationship: location_of CCO:B0054518 ! OR1F1_HUMAN relationship: location_of CCO:B0054520 ! MCAT_HUMAN relationship: location_of CCO:B0054528 ! OR2T1_HUMAN relationship: location_of CCO:B0054529 ! O43898_HUMAN relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: location_of CCO:B0054549 ! FZD6_HUMAN relationship: location_of CCO:B0054552 ! O10H2_HUMAN relationship: location_of CCO:B0054553 ! O10H3_HUMAN relationship: location_of CCO:B0054554 ! O60411_HUMAN relationship: location_of CCO:B0054555 ! OR7C2_HUMAN relationship: location_of CCO:B0054556 ! FADS1_HUMAN relationship: location_of CCO:B0054558 ! OR1I1_HUMAN relationship: location_of CCO:B0054561 ! PLXC1_HUMAN relationship: location_of CCO:B0054569 ! TLR5_HUMAN relationship: location_of CCO:B0054573 ! FAIM3_HUMAN relationship: location_of CCO:B0054576 ! GALR3_HUMAN relationship: location_of CCO:B0054587 ! RAMP1_HUMAN relationship: location_of CCO:B0054589 ! NSMA_HUMAN relationship: location_of CCO:B0054592 ! LIRA1_HUMAN relationship: location_of CCO:B0054594 ! LIRB5_HUMAN relationship: location_of CCO:B0054599 ! PLXA2_HUMAN relationship: location_of CCO:B0054605 ! ICOSL_HUMAN relationship: location_of CCO:B0054613 ! PX11A_HUMAN relationship: location_of CCO:B0054630 ! GPR32_HUMAN relationship: location_of CCO:B0054636 ! USH2A_HUMAN relationship: location_of CCO:B0054640 ! LGR5_HUMAN relationship: location_of CCO:B0054647 ! TNR21_HUMAN relationship: location_of CCO:B0054652 ! ITA10_HUMAN relationship: location_of CCO:B0054666 ! RHBL1_HUMAN relationship: location_of CCO:B0054667 ! RENR_HUMAN relationship: location_of CCO:B0054672 ! LECT1_HUMAN relationship: location_of CCO:B0054684 ! OR2B3_HUMAN relationship: location_of CCO:B0054685 ! OR2J3_HUMAN relationship: location_of CCO:B0054686 ! OR2J2_HUMAN relationship: location_of CCO:B0054688 ! NCTR1_HUMAN relationship: location_of CCO:B0054690 ! S14L2_HUMAN relationship: location_of CCO:B0054694 ! OR7C1_HUMAN relationship: location_of CCO:B0054695 ! OR7AA_HUMAN relationship: location_of CCO:B0054715 ! OR2F2_HUMAN relationship: location_of CCO:B0054716 ! O4F21_HUMAN relationship: location_of CCO:B0054717 ! OR2A4_HUMAN relationship: location_of CCO:B0054718 ! KCNK2_HUMAN relationship: location_of CCO:B0054727 ! S1PR2_HUMAN relationship: location_of CCO:B0054731 ! ZFPL1_HUMAN relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: location_of CCO:B0054736 ! OR5F1_HUMAN relationship: location_of CCO:B0054737 ! OR6A2_HUMAN relationship: location_of CCO:B0054740 ! I18RA_HUMAN relationship: location_of CCO:B0054741 ! KCNH1_HUMAN relationship: location_of CCO:B0054748 ! MPZL1_HUMAN relationship: location_of CCO:B0054752 ! OR2C1_HUMAN relationship: location_of CCO:B0054759 ! CNIH_HUMAN relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: location_of CCO:B0054767 ! LPHN2_HUMAN relationship: location_of CCO:B0054768 ! VNN1_HUMAN relationship: location_of CCO:B0054769 ! O95499_HUMAN relationship: location_of CCO:B0054780 ! NTR2_HUMAN relationship: location_of CCO:B0054781 ! ECEL1_HUMAN relationship: location_of CCO:B0054794 ! GPR75_HUMAN relationship: location_of CCO:B0054804 ! OR2H2_HUMAN relationship: location_of CCO:B0054807 ! NCTR2_HUMAN relationship: location_of CCO:B0054812 ! IGSF6_HUMAN relationship: location_of CCO:B0054813 ! S1PR4_HUMAN relationship: location_of CCO:B0054820 ! PX11B_HUMAN relationship: location_of CCO:B0054856 ! CD8A_HUMAN relationship: location_of CCO:B0054858 ! 2B32_HUMAN relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0054870 ! CO9_HUMAN relationship: location_of CCO:B0054879 ! OPSB_HUMAN relationship: location_of CCO:B0054880 ! OPSR_HUMAN relationship: location_of CCO:B0054881 ! OPSG_HUMAN relationship: location_of CCO:B0054888 ! MAS_HUMAN relationship: location_of CCO:B0054916 ! CD3E_HUMAN relationship: location_of CCO:B0054921 ! TNR16_HUMAN relationship: location_of CCO:B0054929 ! ADRB1_HUMAN relationship: location_of CCO:B0054933 ! IL6RA_HUMAN relationship: location_of CCO:B0054934 ! 5HT1A_HUMAN relationship: location_of CCO:B0054935 ! ABHD2_HUMAN relationship: location_of CCO:B0054937 ! ADA2A_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0054941 ! DOPO_HUMAN relationship: location_of CCO:B0054946 ! CD7_HUMAN relationship: location_of CCO:B0054950 ! TACD2_HUMAN relationship: location_of CCO:B0054951 ! IFI6_HUMAN relationship: location_of CCO:B0054955 ! OR4A8_HUMAN relationship: location_of CCO:B0054956 ! O5AL1_HUMAN relationship: location_of CCO:B0054957 ! OR4Q2_HUMAN relationship: location_of CCO:B0054958 ! OR5G3_HUMAN relationship: location_of CCO:B0054959 ! O10J4_HUMAN relationship: location_of CCO:B0054960 ! OR4E1_HUMAN relationship: location_of CCO:B0054961 ! O52Z1_HUMAN relationship: location_of CCO:B0054964 ! OR9G9_HUMAN relationship: location_of CCO:B0054975 ! PTPRF_HUMAN relationship: location_of CCO:B0054983 ! CD8B_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0054995 ! CD20_HUMAN relationship: location_of CCO:B0055006 ! ACE_HUMAN relationship: location_of CCO:B0055019 ! 2B14_HUMAN relationship: location_of CCO:B0055020 ! ADRB3_HUMAN relationship: location_of CCO:B0055024 ! DRD2_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055039 ! AREG_HUMAN relationship: location_of CCO:B0055047 ! LEUK_HUMAN relationship: location_of CCO:B0055053 ! PRLR_HUMAN relationship: location_of CCO:B0055054 ! TSHR_HUMAN relationship: location_of CCO:B0055084 ! TMM11_HUMAN relationship: location_of CCO:B0055086 ! ANPRC_HUMAN relationship: location_of CCO:B0055092 ! EGLN_HUMAN relationship: location_of CCO:B0055103 ! LAG3_HUMAN relationship: location_of CCO:B0055104 ! ADA2C_HUMAN relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0055108 ! CD53_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055131 ! MAL_HUMAN relationship: location_of CCO:B0055133 ! CNR1_HUMAN relationship: location_of CCO:B0055135 ! SCF_HUMAN relationship: location_of CCO:B0055136 ! DRD1_HUMAN relationship: location_of CCO:B0055138 ! TA2R_HUMAN relationship: location_of CCO:B0055139 ! DRD4_HUMAN relationship: location_of CCO:B0055140 ! DRD5_HUMAN relationship: location_of CCO:B0055145 ! ENPP1_HUMAN relationship: location_of CCO:B0055147 ! FGFR4_HUMAN relationship: location_of CCO:B0055152 ! LSHR_HUMAN relationship: location_of CCO:B0055154 ! ITA6_HUMAN relationship: location_of CCO:B0055157 ! PTPRD_HUMAN relationship: location_of CCO:B0055158 ! PTPRG_HUMAN relationship: location_of CCO:B0055160 ! TNFL4_HUMAN relationship: location_of CCO:B0055175 ! CXCR1_HUMAN relationship: location_of CCO:B0055178 ! FPR3_HUMAN relationship: location_of CCO:B0055179 ! FPR2_HUMAN relationship: location_of CCO:B0055181 ! PTAFR_HUMAN relationship: location_of CCO:B0055182 ! CXCR7_HUMAN relationship: location_of CCO:B0055187 ! NPY1R_HUMAN relationship: location_of CCO:B0055188 ! TNR5_HUMAN relationship: location_of CCO:B0055189 ! ITA3_HUMAN relationship: location_of CCO:B0055191 ! AMFR1_HUMAN relationship: location_of CCO:B0055192 ! NKG2D_HUMAN relationship: location_of CCO:B0055193 ! CD27_HUMAN relationship: location_of CCO:B0055197 ! 5HT1B_HUMAN relationship: location_of CCO:B0055198 ! 5HT2A_HUMAN relationship: location_of CCO:B0055201 ! NMBR_HUMAN relationship: location_of CCO:B0055205 ! 5HT1E_HUMAN relationship: location_of CCO:B0055207 ! CD38_HUMAN relationship: location_of CCO:B0055210 ! AA2AR_HUMAN relationship: location_of CCO:B0055211 ! AA2BR_HUMAN relationship: location_of CCO:B0055218 ! BKRB2_HUMAN relationship: location_of CCO:B0055219 ! V2R_HUMAN relationship: location_of CCO:B0055220 ! TSPO_HUMAN relationship: location_of CCO:B0055221 ! AA1R_HUMAN relationship: location_of CCO:B0055222 ! GRPR_HUMAN relationship: location_of CCO:B0055223 ! AGTR1_HUMAN relationship: location_of CCO:B0055224 ! OXYR_HUMAN relationship: location_of CCO:B0055226 ! 5HT1F_HUMAN relationship: location_of CCO:B0055227 ! OR1E1_HUMAN relationship: location_of CCO:B0055228 ! O10J1_HUMAN relationship: location_of CCO:B0055229 ! GNRHR_HUMAN relationship: location_of CCO:B0055230 ! CALCR_HUMAN relationship: location_of CCO:B0055231 ! NTR1_HUMAN relationship: location_of CCO:B0055247 ! FCG2B_HUMAN relationship: location_of CCO:B0055248 ! I5P2_HUMAN relationship: location_of CCO:B0055251 ! CCKAR_HUMAN relationship: location_of CCO:B0055252 ! GASR_HUMAN relationship: location_of CCO:B0055256 ! CCR1_HUMAN relationship: location_of CCO:B0055257 ! BRS3_HUMAN relationship: location_of CCO:B0055258 ! CCR7_HUMAN relationship: location_of CCO:B0055260 ! CXCR5_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055262 ! CD70_HUMAN relationship: location_of CCO:B0055263 ! TNFL8_HUMAN relationship: location_of CCO:B0055268 ! CD80_HUMAN relationship: location_of CCO:B0055272 ! 5HT7R_HUMAN relationship: location_of CCO:B0055273 ! CNR2_HUMAN relationship: location_of CCO:B0055274 ! TRFR_HUMAN relationship: location_of CCO:B0055275 ! PE2R1_HUMAN relationship: location_of CCO:B0055276 ! CRFR1_HUMAN relationship: location_of CCO:B0055288 ! PE2R4_HUMAN relationship: location_of CCO:B0055289 ! MAS1L_HUMAN relationship: location_of CCO:B0055290 ! APJ_HUMAN relationship: location_of CCO:B0055293 ! DRD3_HUMAN relationship: location_of CCO:B0055295 ! TIE1_HUMAN relationship: location_of CCO:B0055304 ! VGFR3_HUMAN relationship: location_of CCO:B0055305 ! VGFR2_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055313 ! TNR3_HUMAN relationship: location_of CCO:B0055318 ! V1AR_HUMAN relationship: location_of CCO:B0055325 ! ADCY8_HUMAN relationship: location_of CCO:B0055327 ! TPOR_HUMAN relationship: location_of CCO:B0055328 ! CD79B_HUMAN relationship: location_of CCO:B0055335 ! CASR_HUMAN relationship: location_of CCO:B0055338 ! P2RY2_HUMAN relationship: location_of CCO:B0055340 ! TNFL9_HUMAN relationship: location_of CCO:B0055341 ! PACR_HUMAN relationship: location_of CCO:B0055342 ! VIPR2_HUMAN relationship: location_of CCO:B0055343 ! 5HT2B_HUMAN relationship: location_of CCO:B0055346 ! CD86_HUMAN relationship: location_of CCO:B0055354 ! I12R1_HUMAN relationship: location_of CCO:B0055355 ! LIFR_HUMAN relationship: location_of CCO:B0055356 ! NSG1_HUMAN relationship: location_of CCO:B0055358 ! PF2R_HUMAN relationship: location_of CCO:B0055359 ! PE2R2_HUMAN relationship: location_of CCO:B0055367 ! P2RY5_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0055371 ! ABCG1_HUMAN relationship: location_of CCO:B0055372 ! GPR3_HUMAN relationship: location_of CCO:B0055373 ! GPR1_HUMAN relationship: location_of CCO:B0055374 ! XCR1_HUMAN relationship: location_of CCO:B0055378 ! BKRB1_HUMAN relationship: location_of CCO:B0055379 ! IEX1_HUMAN relationship: location_of CCO:B0055382 ! GALR1_HUMAN relationship: location_of CCO:B0055386 ! RGR_HUMAN relationship: location_of CCO:B0055388 ! OR3A1_HUMAN relationship: location_of CCO:B0055389 ! OR3A4_HUMAN relationship: location_of CCO:B0055390 ! OR1G1_HUMAN relationship: location_of CCO:B0055391 ! OR3A2_HUMAN relationship: location_of CCO:B0055393 ! 5HT5A_HUMAN relationship: location_of CCO:B0055395 ! V1BR_HUMAN relationship: location_of CCO:B0055398 ! TNFL6_HUMAN relationship: location_of CCO:B0055400 ! T4S4_HUMAN relationship: location_of CCO:B0055406 ! INAR2_HUMAN relationship: location_of CCO:B0055413 ! CD97_HUMAN relationship: location_of CCO:B0055414 ! G109B_HUMAN relationship: location_of CCO:B0055415 ! CAMLG_HUMAN relationship: location_of CCO:B0055418 ! NPY2R_HUMAN relationship: location_of CCO:B0055419 ! PTH2R_HUMAN relationship: location_of CCO:B0055420 ! CX3C1_HUMAN relationship: location_of CCO:B0055428 ! CXCR3_HUMAN relationship: location_of CCO:B0055429 ! PRLHR_HUMAN relationship: location_of CCO:B0055430 ! GPR15_HUMAN relationship: location_of CCO:B0055435 ! FLT3L_HUMAN relationship: location_of CCO:B0055437 ! TIG1_HUMAN relationship: location_of CCO:B0055439 ! PSN2_HUMAN relationship: location_of CCO:B0055442 ! AGTR2_HUMAN relationship: location_of CCO:B0055446 ! MMP14_HUMAN relationship: location_of CCO:B0055447 ! NPY4R_HUMAN relationship: location_of CCO:B0055449 ! 5HT6R_HUMAN relationship: location_of CCO:B0055455 ! TNF10_HUMAN relationship: location_of CCO:B0055456 ! LU_HUMAN relationship: location_of CCO:B0055468 ! P2RX1_HUMAN relationship: location_of CCO:B0055472 ! CCR3_HUMAN relationship: location_of CCO:B0055473 ! CCR4_HUMAN relationship: location_of CCO:B0055474 ! CCR5_HUMAN relationship: location_of CCO:B0055475 ! CCR6_HUMAN relationship: location_of CCO:B0055476 ! CCR8_HUMAN relationship: location_of CCO:B0055477 ! CCR9_HUMAN relationship: location_of CCO:B0055479 ! CLCN6_HUMAN relationship: location_of CCO:B0055485 ! DGKE_HUMAN relationship: location_of CCO:B0055504 ! NDST2_HUMAN relationship: location_of CCO:B0055519 ! EMP1_HUMAN relationship: location_of CCO:B0055520 ! EMP2_HUMAN relationship: location_of CCO:B0055521 ! EMP3_HUMAN relationship: location_of CCO:B0055526 ! BI1_HUMAN relationship: location_of CCO:B0055533 ! CADH4_HUMAN relationship: location_of CCO:B0055540 ! TPTE_HUMAN relationship: location_of CCO:B0055541 ! ITA1_HUMAN relationship: location_of CCO:B0055544 ! P2RX3_HUMAN relationship: location_of CCO:B0055558 ! SYJ2B_HUMAN relationship: location_of CCO:B0055563 ! KCNKA_HUMAN relationship: location_of CCO:B0055565 ! OR2B6_HUMAN relationship: location_of CCO:B0055566 ! OR4D2_HUMAN relationship: location_of CCO:B0055567 ! O10A3_HUMAN relationship: location_of CCO:B0055568 ! O12D2_HUMAN relationship: location_of CCO:B0055573 ! RHBL3_HUMAN relationship: location_of CCO:B0055576 ! T2R12_HUMAN relationship: location_of CCO:B0055577 ! T2R38_HUMAN relationship: location_of CCO:B0055578 ! T2R39_HUMAN relationship: location_of CCO:B0055579 ! T2R41_HUMAN relationship: location_of CCO:B0055580 ! T2R43_HUMAN relationship: location_of CCO:B0055581 ! T2R44_HUMAN relationship: location_of CCO:B0055582 ! T2R45_HUMAN relationship: location_of CCO:B0055583 ! T2R46_HUMAN relationship: location_of CCO:B0055584 ! T2R47_HUMAN relationship: location_of CCO:B0055585 ! T2R48_HUMAN relationship: location_of CCO:B0055586 ! T2R49_HUMAN relationship: location_of CCO:B0055587 ! T2R50_HUMAN relationship: location_of CCO:B0055588 ! T2R60_HUMAN relationship: location_of CCO:B0055592 ! OR2B8_HUMAN relationship: location_of CCO:B0055599 ! GPR85_HUMAN relationship: location_of CCO:B0055639 ! ACCN2_HUMAN relationship: location_of CCO:B0055645 ! X3CL1_HUMAN relationship: location_of CCO:B0055652 ! I13R1_HUMAN relationship: location_of CCO:B0055669 ! VLDLR_HUMAN relationship: location_of CCO:B0055686 ! IL9R_HUMAN relationship: location_of CCO:B0055687 ! CD83_HUMAN relationship: location_of CCO:B0055688 ! IL5RA_HUMAN relationship: location_of CCO:B0055691 ! ILRL1_HUMAN relationship: location_of CCO:B0055697 ! SC6A3_HUMAN relationship: location_of CCO:B0055699 ! ROR1_HUMAN relationship: location_of CCO:B0055707 ! TNR17_HUMAN relationship: location_of CCO:B0055713 ! GHRHR_HUMAN relationship: location_of CCO:B0055715 ! TIE2_HUMAN relationship: location_of CCO:B0055723 ! UPAR_HUMAN relationship: location_of CCO:B0055724 ! PTHR1_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055740 ! PLP2_HUMAN relationship: location_of CCO:B0055747 ! Q05AH0_HUMAN relationship: location_of CCO:B0055756 ! Q05C50_HUMAN relationship: location_of CCO:B0055770 ! TNFC_HUMAN relationship: location_of CCO:B0055777 ! Q06976_HUMAN relationship: location_of CCO:B0055780 ! TNR9_HUMAN relationship: location_of CCO:B0055781 ! AMPE_HUMAN relationship: location_of CCO:B0055793 ! CD47_HUMAN relationship: location_of CCO:B0055794 ! ADCY1_HUMAN relationship: location_of CCO:B0055813 ! Q0IJ52_HUMAN relationship: location_of CCO:B0055819 ! Q0VAB0_HUMAN relationship: location_of CCO:B0055824 ! ADIG_HUMAN relationship: location_of CCO:B0055836 ! BST2_HUMAN relationship: location_of CCO:B0055844 ! KCNH2_HUMAN relationship: location_of CCO:B0055856 ! PTPRJ_HUMAN relationship: location_of CCO:B0055857 ! KLRB1_HUMAN relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0055864 ! TSN31_HUMAN relationship: location_of CCO:B0055866 ! BAK2_HUMAN relationship: location_of CCO:B0055889 ! KLRD1_HUMAN relationship: location_of CCO:B0055890 ! PD2R_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055895 ! GPR17_HUMAN relationship: location_of CCO:B0055896 ! PTK7_HUMAN relationship: location_of CCO:B0055898 ! CRFR2_HUMAN relationship: location_of CCO:B0055909 ! TMED1_HUMAN relationship: location_of CCO:B0055912 ! MADCA_HUMAN relationship: location_of CCO:B0055913 ! IL18R_HUMAN relationship: location_of CCO:B0055916 ! VPP3_HUMAN relationship: location_of CCO:B0055934 ! OR2F1_HUMAN relationship: location_of CCO:B0055937 ! 5HT4R_HUMAN relationship: location_of CCO:B0055939 ! ITA7_HUMAN relationship: location_of CCO:B0055940 ! AVR2B_HUMAN relationship: location_of CCO:B0055943 ! ITA9_HUMAN relationship: location_of CCO:B0055948 ! Q13850_HUMAN relationship: location_of CCO:B0055975 ! EMR1_HUMAN relationship: location_of CCO:B0055978 ! FKBP8_HUMAN relationship: location_of CCO:B0055979 ! GPR18_HUMAN relationship: location_of CCO:B0055983 ! GP176_HUMAN relationship: location_of CCO:B0055990 ! S29A2_HUMAN relationship: location_of CCO:B0056021 ! Q14868_HUMAN relationship: location_of CCO:B0056027 ! GPNMB_HUMAN relationship: location_of CCO:B0056029 ! Q14968_HUMAN relationship: location_of CCO:B0056042 ! P2RY6_HUMAN relationship: location_of CCO:B0056043 ! RAGE_HUMAN relationship: location_of CCO:B0056046 ! Q15142_HUMAN relationship: location_of CCO:B0056060 ! P2Y14_HUMAN relationship: location_of CCO:B0056078 ! OR1Q1_HUMAN relationship: location_of CCO:B0056079 ! OR4D1_HUMAN relationship: location_of CCO:B0056080 ! OR1C1_HUMAN relationship: location_of CCO:B0056081 ! OR8B8_HUMAN relationship: location_of CCO:B0056082 ! OR7A5_HUMAN relationship: location_of CCO:B0056100 ! LT4R1_HUMAN relationship: location_of CCO:B0056104 ! GPR19_HUMAN relationship: location_of CCO:B0056105 ! NPY5R_HUMAN relationship: location_of CCO:B0056107 ! EFNB3_HUMAN relationship: location_of CCO:B0056132 ! CNGA3_HUMAN relationship: location_of CCO:B0056139 ! Q16503_HUMAN relationship: location_of CCO:B0056146 ! GP162_HUMAN relationship: location_of CCO:B0056153 ! DUFFY_HUMAN relationship: location_of CCO:B0056163 ! STX1A_HUMAN relationship: location_of CCO:B0056178 ! DDR2_HUMAN relationship: location_of CCO:B0056181 ! Q17R53_HUMAN relationship: location_of CCO:B0056182 ! Q17R96_HUMAN relationship: location_of CCO:B0056189 ! Q17S10_HUMAN relationship: location_of CCO:B0056199 ! MICB_HUMAN relationship: location_of CCO:B0056200 ! MICA_HUMAN relationship: location_of CCO:B0056211 ! Q2M3M4_HUMAN relationship: location_of CCO:B0056216 ! Q2MZ38_HUMAN relationship: location_of CCO:B0056219 ! Q2NL85_HUMAN relationship: location_of CCO:B0056221 ! Q2PNZ1_HUMAN relationship: location_of CCO:B0056241 ! OR4FL_HUMAN relationship: location_of CCO:B0056247 ! Q3C1V0_HUMAN relationship: location_of CCO:B0056248 ! 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OR1J2_HUMAN relationship: location_of CCO:B0057746 ! OR1J1_HUMAN relationship: location_of CCO:B0057747 ! O13F1_HUMAN relationship: location_of CCO:B0057748 ! O13C4_HUMAN relationship: location_of CCO:B0057749 ! O13C8_HUMAN relationship: location_of CCO:B0057750 ! O13C5_HUMAN relationship: location_of CCO:B0057751 ! O13C2_HUMAN relationship: location_of CCO:B0057752 ! O13C9_HUMAN relationship: location_of CCO:B0057753 ! OR2K1_HUMAN relationship: location_of CCO:B0057754 ! O13J1_HUMAN relationship: location_of CCO:B0057755 ! OR9A2_HUMAN relationship: location_of CCO:B0057756 ! O2A12_HUMAN relationship: location_of CCO:B0057757 ! OR2A1_HUMAN relationship: location_of CCO:B0057758 ! Q8NGU0_HUMAN relationship: location_of CCO:B0057759 ! OR9A1_HUMAN relationship: location_of CCO:B0057760 ! OR9A4_HUMAN relationship: location_of CCO:B0057761 ! Q8NGU3_HUMAN relationship: location_of CCO:B0057762 ! OR2I1_HUMAN relationship: location_of CCO:B0057763 ! Q8NGU6_HUMAN relationship: location_of CCO:B0057764 ! Q8NGU7_HUMAN relationship: location_of CCO:B0057765 ! GP150_HUMAN relationship: location_of CCO:B0057766 ! OR2Y1_HUMAN relationship: location_of CCO:B0057767 ! Q8NGV8_HUMAN relationship: location_of CCO:B0057768 ! CSRL1_HUMAN relationship: location_of CCO:B0057769 ! OR6B3_HUMAN relationship: location_of CCO:B0057770 ! Q8NGW2_HUMAN relationship: location_of CCO:B0057771 ! Q8NGW3_HUMAN relationship: location_of CCO:B0057772 ! O11L1_HUMAN relationship: location_of CCO:B0057773 ! O2T34_HUMAN relationship: location_of CCO:B0057774 ! O2T35_HUMAN relationship: location_of CCO:B0057775 ! O10T2_HUMAN relationship: location_of CCO:B0057776 ! Q8NGX4_HUMAN relationship: location_of CCO:B0057777 ! O10K1_HUMAN relationship: location_of CCO:B0057778 ! Q8NGX7_HUMAN relationship: location_of CCO:B0057779 ! OR6Y1_HUMAN relationship: location_of CCO:B0057780 ! OR6P1_HUMAN relationship: location_of CCO:B0057781 ! 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Q8NH32_HUMAN relationship: location_of CCO:B0057818 ! Q8NH33_HUMAN relationship: location_of CCO:B0057819 ! Q8NH36_HUMAN relationship: location_of CCO:B0057820 ! OR4C3_HUMAN relationship: location_of CCO:B0057821 ! Q8NH38_HUMAN relationship: location_of CCO:B0057822 ! OR4KD_HUMAN relationship: location_of CCO:B0057823 ! OR4L1_HUMAN relationship: location_of CCO:B0057824 ! Q8NH44_HUMAN relationship: location_of CCO:B0057825 ! Q8NH47_HUMAN relationship: location_of CCO:B0057826 ! OR4X1_HUMAN relationship: location_of CCO:B0057827 ! OR8K3_HUMAN relationship: location_of CCO:B0057828 ! O52N1_HUMAN relationship: location_of CCO:B0057830 ! O52E5_HUMAN relationship: location_of CCO:B0057831 ! O52N5_HUMAN relationship: location_of CCO:B0057832 ! O52P1_HUMAN relationship: location_of CCO:B0057833 ! Q8NH58_HUMAN relationship: location_of CCO:B0057834 ! O51Q1_HUMAN relationship: location_of CCO:B0057835 ! O52J3_HUMAN relationship: location_of CCO:B0057836 ! Q8NH62_HUMAN relationship: location_of CCO:B0057837 ! O51H1_HUMAN relationship: location_of CCO:B0057838 ! O51A7_HUMAN relationship: location_of CCO:B0057839 ! Q8NH66_HUMAN relationship: location_of CCO:B0057840 ! Q8NH68_HUMAN relationship: location_of CCO:B0057841 ! O4A16_HUMAN relationship: location_of CCO:B0057842 ! Q8NH71_HUMAN relationship: location_of CCO:B0057843 ! OR4C6_HUMAN relationship: location_of CCO:B0057845 ! O10A6_HUMAN relationship: location_of CCO:B0057846 ! Q8NH75_HUMAN relationship: location_of CCO:B0057847 ! O56B4_HUMAN relationship: location_of CCO:B0057848 ! Q8NH77_HUMAN relationship: location_of CCO:B0057849 ! Q8NH78_HUMAN relationship: location_of CCO:B0057850 ! OR6X1_HUMAN relationship: location_of CCO:B0057851 ! O10D3_HUMAN relationship: location_of CCO:B0057852 ! O10G6_HUMAN relationship: location_of CCO:B0057853 ! Q8NH82_HUMAN relationship: location_of CCO:B0057854 ! OR4A5_HUMAN relationship: location_of CCO:B0057855 ! Q8NH84_HUMAN relationship: location_of CCO:B0057856 ! Q8NH86_HUMAN relationship: location_of CCO:B0057857 ! OR9G1_HUMAN relationship: location_of CCO:B0057858 ! Q8NH88_HUMAN relationship: location_of CCO:B0057859 ! OR1L3_HUMAN relationship: location_of CCO:B0057860 ! YI035_HUMAN relationship: location_of CCO:B0057861 ! O2AE1_HUMAN relationship: location_of CCO:B0057862 ! OR2W6_HUMAN relationship: location_of CCO:B0057863 ! Q8NHA7_HUMAN relationship: location_of CCO:B0057864 ! OR1FC_HUMAN relationship: location_of CCO:B0057865 ! Q8NHB0_HUMAN relationship: location_of CCO:B0057866 ! OR2V1_HUMAN relationship: location_of CCO:B0057867 ! Q8NHB3_HUMAN relationship: location_of CCO:B0057868 ! Q8NHC2_HUMAN relationship: location_of CCO:B0057869 ! Q8NHC3_HUMAN relationship: location_of CCO:B0057870 ! O10J5_HUMAN relationship: location_of CCO:B0057871 ! O14AG_HUMAN relationship: location_of CCO:B0057872 ! O14L1_HUMAN relationship: location_of CCO:B0057873 ! O14CZ_HUMAN relationship: location_of CCO:B0057874 ! OR2T6_HUMAN relationship: location_of CCO:B0057875 ! LIRB4_HUMAN relationship: location_of CCO:B0057878 ! B4GN2_HUMAN relationship: location_of CCO:B0057882 ! Q8NI49_HUMAN relationship: location_of CCO:B0057883 ! Q8NI50_HUMAN relationship: location_of CCO:B0057894 ! STML3_HUMAN relationship: location_of CCO:B0057902 ! CNIH3_HUMAN relationship: location_of CCO:B0057913 ! O51E1_HUMAN relationship: location_of CCO:B0057917 ! PKR1_HUMAN relationship: location_of CCO:B0057919 ! PKHD1_HUMAN relationship: location_of CCO:B0057929 ! Q8TDP6_HUMAN relationship: location_of CCO:B0057930 ! Q8TDP8_HUMAN relationship: location_of CCO:B0057932 ! G109A_HUMAN relationship: location_of CCO:B0057933 ! OXER1_HUMAN relationship: location_of CCO:B0057934 ! MRGRD_HUMAN relationship: location_of CCO:B0057935 ! GP152_HUMAN relationship: location_of CCO:B0057936 ! Q8TDT4_HUMAN relationship: location_of CCO:B0057937 ! Q8TDT9_HUMAN relationship: location_of CCO:B0057938 ! VNRL4_HUMAN relationship: location_of CCO:B0057939 ! GPBAR_HUMAN relationship: location_of CCO:B0057940 ! RL3R2_HUMAN relationship: location_of CCO:B0057941 ! GP151_HUMAN relationship: location_of CCO:B0057942 ! Q8TDV1_HUMAN relationship: location_of CCO:B0057943 ! GP148_HUMAN relationship: location_of CCO:B0057944 ! GP119_HUMAN relationship: location_of CCO:B0057945 ! CGAT1_HUMAN relationship: location_of CCO:B0057950 ! TS1R2_HUMAN relationship: location_of CCO:B0057954 ! RN128_HUMAN relationship: location_of CCO:B0057958 ! CR3L4_HUMAN relationship: location_of CCO:B0057970 ! Q8WTR3_HUMAN relationship: location_of CCO:B0057978 ! CHPT1_HUMAN relationship: location_of CCO:B0057985 ! NAT14_HUMAN relationship: location_of CCO:B0057996 ! SCTM1_HUMAN relationship: location_of CCO:B0057997 ! CANT1_HUMAN relationship: location_of CCO:B0058000 ! APH1B_HUMAN relationship: location_of CCO:B0058012 ! Q8WX98_HUMAN relationship: location_of CCO:B0058018 ! GPR98_HUMAN relationship: location_of CCO:B0058025 ! Q8WXJ7_HUMAN relationship: location_of CCO:B0058031 ! Q8WXL5_HUMAN relationship: location_of CCO:B0058032 ! Q8WXL8_HUMAN relationship: location_of CCO:B0058033 ! Q8WXN2_HUMAN relationship: location_of CCO:B0058034 ! Q8WXV1_HUMAN relationship: location_of CCO:B0058035 ! Q8WXV2_HUMAN relationship: location_of CCO:B0058036 ! Q8WXZ9_HUMAN relationship: location_of CCO:B0058042 ! CNTP5_HUMAN relationship: location_of CCO:B0058051 ! ROBO4_HUMAN relationship: location_of CCO:B0058052 ! OR8D1_HUMAN relationship: location_of CCO:B0058053 ! OR5P2_HUMAN relationship: location_of CCO:B0058054 ! OR5P3_HUMAN relationship: location_of CCO:B0058056 ! OR1E3_HUMAN relationship: location_of CCO:B0058057 ! AQP3_HUMAN relationship: location_of CCO:B0058059 ! CPT1B_HUMAN relationship: location_of CCO:B0058062 ! NICA_HUMAN relationship: location_of CCO:B0058076 ! LPAR1_HUMAN relationship: location_of CCO:B0058097 ! IOD2_HUMAN relationship: location_of CCO:B0058102 ! EDA_HUMAN relationship: location_of CCO:B0058105 ! GHSR_HUMAN relationship: location_of CCO:B0058110 ! CDS1_HUMAN relationship: location_of CCO:B0058119 ! Q93003_HUMAN relationship: location_of CCO:B0058120 ! IGSF2_HUMAN relationship: location_of CCO:B0058121 ! TNR25_HUMAN relationship: location_of CCO:B0058122 ! P2RX5_HUMAN relationship: location_of CCO:B0058129 ! KISSR_HUMAN relationship: location_of CCO:B0058135 ! TAAR8_HUMAN relationship: location_of CCO:B0058141 ! MCHR2_HUMAN relationship: location_of CCO:B0058142 ! MUL1_HUMAN relationship: location_of CCO:B0058144 ! PMEPA_HUMAN relationship: location_of CCO:B0058156 ! ECOP_HUMAN relationship: location_of CCO:B0058161 ! CR3L1_HUMAN relationship: location_of CCO:B0058164 ! APH1A_HUMAN relationship: location_of CCO:B0058172 ! TBC20_HUMAN relationship: location_of CCO:B0058182 ! 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OR2A7_HUMAN relationship: location_of CCO:B0058363 ! O2A14_HUMAN relationship: location_of CCO:B0058364 ! OR2A5_HUMAN relationship: location_of CCO:B0058365 ! O14A2_HUMAN relationship: location_of CCO:B0058366 ! OR4CC_HUMAN relationship: location_of CCO:B0058367 ! OR4F4_HUMAN relationship: location_of CCO:B0058368 ! OR4K3_HUMAN relationship: location_of CCO:B0058369 ! OR1F2_HUMAN relationship: location_of CCO:B0058370 ! OR7D2_HUMAN relationship: location_of CCO:B0058371 ! OR8B2_HUMAN relationship: location_of CCO:B0058372 ! OR6C1_HUMAN relationship: location_of CCO:B0058373 ! O52E6_HUMAN relationship: location_of CCO:B0058377 ! TAAR6_HUMAN relationship: location_of CCO:B0058378 ! TAAR9_HUMAN relationship: location_of CCO:B0058379 ! TAAR1_HUMAN relationship: location_of CCO:B0058396 ! Q96SZ0_HUMAN relationship: location_of CCO:B0058407 ! CSF3R_HUMAN relationship: location_of CCO:B0058413 ! NPY6R_HUMAN relationship: location_of CCO:B0058414 ! NOTC4_HUMAN relationship: location_of CCO:B0058418 ! S1PR3_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058422 ! GPER_HUMAN relationship: location_of CCO:B0058423 ! P2RX4_HUMAN relationship: location_of CCO:B0058433 ! Q99642_HUMAN relationship: location_of CCO:B0058436 ! Q99662_HUMAN relationship: location_of CCO:B0058438 ! GPR20_HUMAN relationship: location_of CCO:B0058439 ! GPR21_HUMAN relationship: location_of CCO:B0058440 ! GPR22_HUMAN relationship: location_of CCO:B0058444 ! MCHR1_HUMAN relationship: location_of CCO:B0058445 ! KI2L4_HUMAN relationship: location_of CCO:B0058450 ! MGST2_HUMAN relationship: location_of CCO:B0058454 ! CML1_HUMAN relationship: location_of CCO:B0058463 ! ATF6B_HUMAN relationship: location_of CCO:B0058469 ! P2Y13_HUMAN relationship: location_of CCO:B0058480 ! SELS_HUMAN relationship: location_of CCO:B0058482 ! PSD2_HUMAN relationship: location_of CCO:B0058494 ! AIFM2_HUMAN relationship: location_of CCO:B0058512 ! NFIP1_HUMAN relationship: location_of CCO:B0058545 ! Q9BX81_HUMAN relationship: location_of CCO:B0058548 ! LGR4_HUMAN relationship: location_of CCO:B0058549 ! GPR81_HUMAN relationship: location_of CCO:B0058550 ! GP174_HUMAN relationship: location_of CCO:B0058551 ! VN1R3_HUMAN relationship: location_of CCO:B0058561 ! CLC7A_HUMAN relationship: location_of CCO:B0058565 ! EMR3_HUMAN relationship: location_of CCO:B0058566 ! M4A8B_HUMAN relationship: location_of CCO:B0058567 ! GPR87_HUMAN relationship: location_of CCO:B0058577 ! PCD24_HUMAN relationship: location_of CCO:B0058578 ! ACE2_HUMAN relationship: location_of CCO:B0058590 ! CNTP3_HUMAN relationship: location_of CCO:B0058591 ! Q9BZ77_HUMAN relationship: location_of CCO:B0058594 ! Q9BZC5_HUMAN relationship: location_of CCO:B0058600 ! GPR63_HUMAN relationship: location_of CCO:B0058601 ! GPR62_HUMAN relationship: location_of CCO:B0058602 ! GPR61_HUMAN relationship: location_of CCO:B0058624 ! OR2B2_HUMAN relationship: location_of CCO:B0058625 ! OR2H1_HUMAN relationship: location_of CCO:B0058626 ! OR2J1_HUMAN relationship: location_of CCO:B0058627 ! O11A1_HUMAN relationship: location_of CCO:B0058629 ! GPR88_HUMAN relationship: location_of CCO:B0058630 ! VN1R1_HUMAN relationship: location_of CCO:B0058631 ! DERL2_HUMAN relationship: location_of CCO:B0058632 ! NMUR2_HUMAN relationship: location_of CCO:B0058633 ! NPFF1_HUMAN relationship: location_of CCO:B0058646 ! ACH10_HUMAN relationship: location_of CCO:B0058663 ! LPAR5_HUMAN relationship: location_of CCO:B0058667 ! OPN3_HUMAN relationship: location_of CCO:B0058668 ! O2AG1_HUMAN relationship: location_of CCO:B0058669 ! O10A5_HUMAN relationship: location_of CCO:B0058670 ! O10A2_HUMAN relationship: location_of CCO:B0058671 ! O10A4_HUMAN relationship: location_of CCO:B0058672 ! OR2D2_HUMAN relationship: location_of CCO:B0058673 ! S1PR5_HUMAN relationship: location_of CCO:B0058674 ! PORCN_HUMAN relationship: location_of CCO:B0058675 ! P2Y12_HUMAN relationship: location_of CCO:B0058676 ! KCNH6_HUMAN relationship: location_of CCO:B0058678 ! O51E2_HUMAN relationship: location_of CCO:B0058681 ! O52A5_HUMAN relationship: location_of CCO:B0058682 ! Q9H2C6_HUMAN relationship: location_of CCO:B0058683 ! O51V1_HUMAN relationship: location_of CCO:B0058685 ! SEM6A_HUMAN relationship: location_of CCO:B0058689 ! M4A6A_HUMAN relationship: location_of CCO:B0058691 ! CLC4M_HUMAN relationship: location_of CCO:B0058694 ! O51B5_HUMAN relationship: location_of CCO:B0058695 ! O51B6_HUMAN relationship: location_of CCO:B0058696 ! O51M1_HUMAN relationship: location_of CCO:B0058697 ! O51J1_HUMAN relationship: location_of CCO:B0058698 ! O51I1_HUMAN relationship: location_of CCO:B0058699 ! O51I2_HUMAN relationship: location_of CCO:B0058700 ! Q9H345_HUMAN relationship: location_of CCO:B0058701 ! O52D1_HUMAN relationship: location_of CCO:B0058704 ! Q9H3K3_HUMAN relationship: location_of CCO:B0058705 ! TXND1_HUMAN relationship: location_of CCO:B0058706 ! HRH4_HUMAN relationship: location_of CCO:B0058711 ! MS4A5_HUMAN relationship: location_of CCO:B0058743 ! Q9H7Q2_HUMAN relationship: location_of CCO:B0058770 ! TNR27_HUMAN relationship: location_of CCO:B0058773 ! ILRL2_HUMAN relationship: location_of CCO:B0058775 ! Q9HB42_HUMAN relationship: location_of CCO:B0058776 ! Q9HB44_HUMAN relationship: location_of CCO:B0058780 ! NMUR1_HUMAN relationship: location_of CCO:B0058793 ! ELTD1_HUMAN relationship: location_of CCO:B0058808 ! NGL1_HUMAN relationship: location_of CCO:B0058810 ! ROBO2_HUMAN relationship: location_of CCO:B0058812 ! PLXA4_HUMAN relationship: location_of CCO:B0058814 ! GPVI_HUMAN relationship: location_of CCO:B0058815 ! HHATL_HUMAN relationship: location_of CCO:B0058819 ! PREB_HUMAN relationship: location_of CCO:B0058824 ! Q9HD50_HUMAN relationship: location_of CCO:B0058829 ! CD209_HUMAN relationship: location_of CCO:B0058832 ! IRPL2_HUMAN relationship: location_of CCO:B0058838 ! TNR12_HUMAN relationship: location_of CCO:B0058842 ! TREM1_HUMAN relationship: location_of CCO:B0058846 ! LT4R2_HUMAN relationship: location_of CCO:B0058849 ! CD320_HUMAN relationship: location_of CCO:B0058851 ! FZD3_HUMAN relationship: location_of CCO:B0058853 ! IL1AP_HUMAN relationship: location_of CCO:B0058854 ! NOX4_HUMAN relationship: location_of CCO:B0058858 ! SLAF7_HUMAN relationship: location_of CCO:B0058861 ! TMM9B_HUMAN relationship: location_of CCO:B0058869 ! OR2S1_HUMAN relationship: location_of CCO:B0058872 ! GPR84_HUMAN relationship: location_of CCO:B0058877 ! CNGB3_HUMAN relationship: location_of CCO:B0058888 ! ASAH2_HUMAN relationship: location_of CCO:B0058891 ! TLR9_HUMAN relationship: location_of CCO:B0058892 ! TLR8_HUMAN relationship: location_of CCO:B0058893 ! Q9NRB8_HUMAN relationship: location_of CCO:B0058896 ! DUOX2_HUMAN relationship: location_of CCO:B0058897 ! DUOX1_HUMAN relationship: location_of CCO:B0058909 ! GP173_HUMAN relationship: location_of CCO:B0058910 ! GPR27_HUMAN relationship: location_of CCO:B0058911 ! TNR19_HUMAN relationship: location_of CCO:B0058916 ! Q9NSC9_HUMAN relationship: location_of CCO:B0058918 ! RL3R1_HUMAN relationship: location_of CCO:B0058922 ! Q9NSM3_HUMAN relationship: location_of CCO:B0058925 ! AT8A2_HUMAN relationship: location_of CCO:B0058930 ! NFIP2_HUMAN relationship: location_of CCO:B0058948 ! RHBL2_HUMAN relationship: location_of CCO:B0058954 ! M4A12_HUMAN relationship: location_of CCO:B0058957 ! CLC5A_HUMAN relationship: location_of CCO:B0058965 ! GPR83_HUMAN relationship: location_of CCO:B0058967 ! Q9NYN8_HUMAN relationship: location_of CCO:B0058975 ! T2R16_HUMAN relationship: location_of CCO:B0058976 ! T2R14_HUMAN relationship: location_of CCO:B0058977 ! T2R13_HUMAN relationship: location_of CCO:B0058978 ! T2R10_HUMAN relationship: location_of CCO:B0058979 ! TA2R9_HUMAN relationship: location_of CCO:B0058980 ! TA2R8_HUMAN relationship: location_of CCO:B0058981 ! TA2R7_HUMAN relationship: location_of CCO:B0058982 ! TA2R4_HUMAN relationship: location_of CCO:B0058983 ! TA2R3_HUMAN relationship: location_of CCO:B0058984 ! TA2R1_HUMAN relationship: location_of CCO:B0058988 ! SIGL8_HUMAN relationship: location_of CCO:B0058989 ! PEN2_HUMAN relationship: location_of CCO:B0058993 ! GPC5D_HUMAN relationship: location_of CCO:B0058996 ! GPC5B_HUMAN relationship: location_of CCO:B0059001 ! MTCH1_HUMAN relationship: location_of CCO:B0059005 ! IRPL1_HUMAN relationship: location_of CCO:B0059007 ! OR6C3_HUMAN relationship: location_of CCO:B0059008 ! OR6C2_HUMAN relationship: location_of CCO:B0059011 ! PD1L1_HUMAN relationship: location_of CCO:B0059014 ! KLRF1_HUMAN relationship: location_of CCO:B0059015 ! BFAR_HUMAN relationship: location_of CCO:B0059024 ! CNIH4_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0059029 ! VAPA_HUMAN relationship: location_of CCO:B0059035 ! CAC1I_HUMAN relationship: location_of CCO:B0059038 ! TAAR3_HUMAN relationship: location_of CCO:B0059039 ! TAAR2_HUMAN relationship: location_of CCO:B0059040 ! OR1A1_HUMAN relationship: location_of CCO:B0059044 ! Q9P1V4_HUMAN relationship: location_of CCO:B0059045 ! SIRPG_HUMAN relationship: location_of CCO:B0059074 ! XPR1_HUMAN relationship: location_of CCO:B0059076 ! P2RX2_HUMAN relationship: location_of CCO:B0059077 ! PEMT_HUMAN relationship: location_of CCO:B0059078 ! DHCR7_HUMAN relationship: location_of CCO:B0059079 ! TR10D_HUMAN relationship: location_of CCO:B0059082 ! CKLF_HUMAN relationship: location_of CCO:B0059086 ! SE1L1_HUMAN relationship: location_of CCO:B0059087 ! B4GT7_HUMAN relationship: location_of CCO:B0059091 ! CLN8_HUMAN relationship: location_of CCO:B0059102 ! Q9UDD7_HUMAN relationship: location_of CCO:B0059103 ! Q9UDF1_HUMAN relationship: location_of CCO:B0059108 ! KLOT_HUMAN relationship: location_of CCO:B0059110 ! VTI1B_HUMAN relationship: location_of CCO:B0059113 ! MARCO_HUMAN relationship: location_of CCO:B0059120 ! O14J1_HUMAN relationship: location_of CCO:B0059121 ! OR5V1_HUMAN relationship: location_of CCO:B0059122 ! O12D3_HUMAN relationship: location_of CCO:B0059135 ! CNTP2_HUMAN relationship: location_of CCO:B0059146 ! CLC2D_HUMAN relationship: location_of CCO:B0059152 ! EMR2_HUMAN relationship: location_of CCO:B0059168 ! GP160_HUMAN relationship: location_of CCO:B0059195 ! O52A1_HUMAN relationship: location_of CCO:B0059196 ! MUC12_HUMAN relationship: location_of CCO:B0059199 ! UR2R_HUMAN relationship: location_of CCO:B0059201 ! ACSL6_HUMAN relationship: location_of CCO:B0059202 ! TRHDE_HUMAN relationship: location_of CCO:B0059206 ! AMFR2_HUMAN relationship: location_of CCO:B0059212 ! Q9UL14_HUMAN relationship: location_of CCO:B0059223 ! KCNH3_HUMAN relationship: location_of CCO:B0059233 ! FZD4_HUMAN relationship: location_of CCO:B0059240 ! Q9UM77_HUMAN relationship: location_of CCO:B0059241 ! CLC4A_HUMAN relationship: location_of CCO:B0059250 ! EDAR_HUMAN relationship: location_of CCO:B0059259 ! GPR34_HUMAN relationship: location_of CCO:B0059273 ! KCNH4_HUMAN relationship: location_of CCO:B0059286 ! LAMP3_HUMAN relationship: location_of CCO:B0059296 ! TN13B_HUMAN relationship: location_of CCO:B0059297 ! VSIG4_HUMAN relationship: location_of CCO:B0059302 ! CK009_HUMAN relationship: location_of CCO:B0059316 ! GPR52_HUMAN relationship: location_of CCO:B0059317 ! GPR55_HUMAN relationship: location_of CCO:B0059327 ! GPR89_HUMAN relationship: location_of CCO:B0059328 ! NSG2_HUMAN relationship: location_of CCO:B0059330 ! SIGL9_HUMAN relationship: location_of CCO:B0059331 ! Q9Y347_HUMAN relationship: location_of CCO:B0059335 ! GOT1B_HUMAN relationship: location_of CCO:B0059341 ! OR2W1_HUMAN relationship: location_of CCO:B0059356 ! O10H1_HUMAN relationship: location_of CCO:B0059359 ! PLXD1_HUMAN relationship: location_of CCO:B0059369 ! LRP12_HUMAN relationship: location_of CCO:B0059374 ! OR1A2_HUMAN relationship: location_of CCO:B0059379 ! HRH3_HUMAN relationship: location_of CCO:B0059380 ! O51B4_HUMAN relationship: location_of CCO:B0059381 ! O51B2_HUMAN relationship: location_of CCO:B0059386 ! NOX1_HUMAN relationship: location_of CCO:B0059387 ! TNR18_HUMAN relationship: location_of CCO:B0059392 ! NPFF2_HUMAN relationship: location_of CCO:B0059393 ! GPR44_HUMAN relationship: location_of CCO:B0059394 ! BACE2_HUMAN relationship: location_of CCO:B0059397 ! GPR56_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0061994 ! F173A_HUMAN relationship: location_of CCO:B0062770 ! ZDHC3_HUMAN relationship: location_of CCO:B0062773 ! ITM2C_HUMAN relationship: location_of CCO:B0062774 ! S22AO_HUMAN relationship: location_of CCO:B0062787 ! STX8_HUMAN relationship: location_of CCO:B0062798 ! BAMBI_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062827 ! LRRN4_HUMAN relationship: location_of CCO:B0062832 ! EAA3_HUMAN relationship: location_of CCO:B0062835 ! Q8IV21_HUMAN relationship: location_of CCO:B0062839 ! TM147_HUMAN relationship: location_of CCO:B0062844 ! AQP5_HUMAN relationship: location_of CCO:B0062846 ! RN183_HUMAN relationship: location_of CCO:B0062852 ! KELL_HUMAN relationship: location_of CCO:B0062855 ! MFSD3_HUMAN relationship: location_of CCO:B0062879 ! CTSR1_HUMAN relationship: location_of CCO:B0062893 ! SAM50_HUMAN relationship: location_of CCO:B0062902 ! NPDC1_HUMAN relationship: location_of CCO:B0062906 ! SERP2_HUMAN relationship: location_of CCO:B0062910 ! FATE1_HUMAN relationship: location_of CCO:B0062929 ! MALL_HUMAN relationship: location_of CCO:B0062933 ! TSN3_HUMAN relationship: location_of CCO:B0062940 ! LERL1_HUMAN relationship: location_of CCO:B0062962 ! KCMB1_HUMAN relationship: location_of CCO:B0062964 ! TEX28_HUMAN relationship: location_of CCO:B0062981 ! LAIR1_HUMAN relationship: location_of CCO:B0062990 ! SFXN3_HUMAN relationship: location_of CCO:B0062993 ! MDR1_HUMAN relationship: location_of CCO:B0062994 ! ERAP1_HUMAN relationship: location_of CCO:B0063007 ! ANTR2_HUMAN relationship: location_of CCO:B0063062 ! SFXN1_HUMAN relationship: location_of CCO:B0063067 ! CALX_HUMAN relationship: location_of CCO:B0063081 ! SSRD_HUMAN relationship: location_of CCO:B0063133 ! BRI3B_HUMAN relationship: location_of CCO:B0063139 ! GSLG1_HUMAN relationship: location_of CCO:B0063145 ! CTLA4_HUMAN relationship: location_of CCO:B0063146 ! I10R1_HUMAN relationship: location_of CCO:B0063160 ! COMT_HUMAN relationship: location_of CCO:B0063164 ! CC136_HUMAN relationship: location_of CCO:B0063192 ! TRPC3_HUMAN relationship: location_of CCO:B0063197 ! MUC13_HUMAN relationship: location_of CCO:B0063198 ! SORL_HUMAN relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0063205 ! TACD1_HUMAN relationship: location_of CCO:B0063222 ! OSTA_HUMAN relationship: location_of CCO:B0063227 ! MEP1B_HUMAN relationship: location_of CCO:B0063229 ! SCRB1_HUMAN relationship: location_of CCO:B0063239 ! ICAM3_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0063248 ! HA25_HUMAN relationship: location_of CCO:B0063249 ! HB25_HUMAN relationship: location_of CCO:B0063256 ! TMM33_HUMAN relationship: location_of CCO:B0063267 ! ACCN1_HUMAN relationship: location_of CCO:B0063273 ! GHR_HUMAN relationship: location_of CCO:B0063275 ! ZDHC7_HUMAN relationship: location_of CCO:B0063288 ! B3GN9_HUMAN relationship: location_of CCO:B0063292 ! SAP_HUMAN relationship: location_of CCO:B0063298 ! PPLA_HUMAN relationship: location_of CCO:B0063303 ! VPP2_HUMAN relationship: location_of CCO:B0063307 ! CLC4F_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063322 ! ENTP6_HUMAN relationship: location_of CCO:B0063334 ! ERG25_HUMAN relationship: location_of CCO:B0063336 ! SIA7F_HUMAN relationship: location_of CCO:B0063340 ! 2DRA_HUMAN relationship: location_of CCO:B0063351 ! TRPC7_HUMAN relationship: location_of CCO:B0063358 ! ADT1_HUMAN relationship: location_of CCO:B0063379 ! F134A_HUMAN relationship: location_of CCO:B0063384 ! MA2A2_HUMAN relationship: location_of CCO:B0063388 ! PEX2_HUMAN relationship: location_of CCO:B0063389 ! T4S1_HUMAN relationship: location_of CCO:B0063390 ! TMPS3_HUMAN relationship: location_of CCO:B0063396 ! VAS1_HUMAN relationship: location_of CCO:B0063402 ! CI046_HUMAN relationship: location_of CCO:B0063411 ! F176A_HUMAN relationship: location_of CCO:B0063418 ! PPA5_HUMAN relationship: location_of CCO:B0063432 ! RER1_HUMAN relationship: location_of CCO:B0063442 ! TUTLA_HUMAN relationship: location_of CCO:B0063449 ! STT3A_HUMAN relationship: location_of CCO:B0063455 ! EPCR_HUMAN relationship: location_of CCO:B0063459 ! GOLI_HUMAN relationship: location_of CCO:B0063471 ! TM216_HUMAN relationship: location_of CCO:B0063476 ! PTHD2_HUMAN relationship: location_of CCO:B0063478 ! FXYD3_HUMAN relationship: location_of CCO:B0063481 ! PIGC_HUMAN relationship: location_of CCO:B0063486 ! PRRT2_HUMAN relationship: location_of CCO:B0063495 ! S2538_HUMAN relationship: location_of CCO:B0063504 ! CAH12_HUMAN relationship: location_of CCO:B0063511 ! Q96I30_HUMAN relationship: location_of CCO:B0063527 ! CDAN1_HUMAN relationship: location_of CCO:B0063532 ! APMAP_HUMAN relationship: location_of CCO:B0063598 ! ARMS_HUMAN-Phosphoserine918 relationship: location_of CCO:B0063640 ! AT10A_HUMAN-Phosphoserine646 relationship: location_of CCO:B0063642 ! AT1A3_HUMAN-Phosphothreonine368 relationship: location_of CCO:B0063708 ! BAI3_HUMAN-Phosphoserine1220 relationship: location_of CCO:B0063733 ! BASI_HUMAN-Phosphoserine362 relationship: location_of CCO:B0063923 ! BIG3_HUMAN-Phosphoserine1651 relationship: location_of CCO:B0064022 ! C3AR_HUMAN-Sulfotyrosine174 relationship: location_of CCO:B0064025 ! C5ARL_HUMAN-Phosphoserine326 relationship: location_of CCO:B0064030 ! C5AR_HUMAN-Phosphoserine327 relationship: location_of CCO:B0064043 ! CAC1D_HUMAN-Phosphoserine1475 relationship: location_of CCO:B0064121 ! CCR10_HUMAN-Phosphothreonine295 relationship: location_of CCO:B0064123 ! CCR2_HUMAN-Sulfotyrosine26 relationship: location_of CCO:B0064135 ! CD19_HUMAN-Phosphotyrosine378 relationship: location_of CCO:B0064139 ! CD226_HUMAN-Phosphoserine290 relationship: location_of CCO:B0064141 ! CD244_HUMAN-Phosphotyrosine271 relationship: location_of CCO:B0064151 ! CD33_HUMAN-Phosphotyrosine340 relationship: location_of CCO:B0064154 ! CD3D_HUMAN-Phosphotyrosine160 relationship: location_of CCO:B0064160 ! CD3G_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0064164 ! CD3Z_HUMAN-Phosphotyrosine83 relationship: location_of CCO:B0064171 ! CD5_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0064255 ! CELR1_HUMAN-Phosphoserine2761 relationship: location_of CCO:B0064367 ! CKAP4_HUMAN-Phosphoserine312 relationship: location_of CCO:B0064377 ! CLC1B_HUMAN-Phosphotyrosine7 relationship: location_of CCO:B0064391 ! CLN6_HUMAN-Phosphoserine31 relationship: location_of CCO:B0064430 ! CNTP1_HUMAN-Phosphoserine1383 relationship: location_of CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064461 ! CR3L3_HUMAN-Phosphoserine256 relationship: location_of CCO:B0064467 ! CRIM1_HUMAN-Phosphothreonine1035 relationship: location_of CCO:B0064552 ! CSF1R_HUMAN-Phosphothreonine562 relationship: location_of CCO:B0064565 ! CSPG4_HUMAN-Phosphothreonine21 relationship: location_of CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: location_of CCO:B0064624 ! DAD1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0064741 ! DERL1_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0064792 ! DNER_HUMAN-Phosphotyrosine718 relationship: location_of CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: location_of CCO:B0065041 ! ELOA1_HUMAN-Phosphoserine125 relationship: location_of CCO:B0065089 ! EPHB3_HUMAN-Phosphotyrosine600 relationship: location_of CCO:B0065098 ! EPOR_HUMAN-Phosphotyrosine504 relationship: location_of CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 relationship: location_of CCO:B0065165 ! ETBR2_HUMAN-Phosphoserine471 relationship: location_of CCO:B0065229 ! AA3R_HUMAN-Phosphoserine317 relationship: location_of CCO:B0065230 ! AAAT_HUMAN-Phosphoserine535 relationship: location_of CCO:B0065266 ! ABCA2_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0065314 ! ACCN3_HUMAN-Phosphoserine521 relationship: location_of CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: location_of CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: location_of CCO:B0065389 ! ACSL1_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0065404 ! ADCY5_HUMAN-Phosphoserine8 relationship: location_of CCO:B0065406 ! ADCY6_HUMAN-Phosphoserine576 relationship: location_of CCO:B0065409 ! ADCY9_HUMAN-Phosphoserine610 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0065450 ! ADT3_HUMAN-N-acetylthreonine2 relationship: location_of CCO:B0065648 ! ANTR1_HUMAN-Phosphotyrosine425 relationship: location_of CCO:B0065810 ! CAD10_HUMAN-Phosphoserine784 relationship: location_of CCO:B0065817 ! CALY_HUMAN-Phosphotyrosine151 relationship: location_of CCO:B0065843 ! CD22_HUMAN-Phosphotyrosine762 relationship: location_of CCO:B0065880 ! CLD12_HUMAN-Phosphoserine228 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: location_of CCO:B0066003 ! EMD_HUMAN-Phosphotyrosine105 relationship: location_of CCO:B0066029 ! ESYT1_HUMAN-Phosphoserine1034 relationship: location_of CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: location_of CCO:B0066149 ! FCERG_HUMAN-Phosphotyrosine76 relationship: location_of CCO:B0066152 ! FCGR1_HUMAN-Phosphotyrosine138 relationship: location_of CCO:B0066173 ! FFAR1_HUMAN-Phosphotyrosine44 relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0066508 ! GOGB1_HUMAN-Phosphoserine17 relationship: location_of CCO:B0066524 ! GP125_HUMAN-Phosphothreonine208 relationship: location_of CCO:B0066526 ! GP126_HUMAN-Phosphoserine1165 relationship: location_of CCO:B0066528 ! GP155_HUMAN-Phosphotyrosine451 relationship: location_of CCO:B0066536 ! GP1BB_HUMAN-Phosphothreonine193 relationship: location_of CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 relationship: location_of CCO:B0066544 ! GPR12_HUMAN-Phosphoserine332 relationship: location_of CCO:B0066549 ! GPR6_HUMAN-Phosphoserine356 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066606 ! GRIA2_HUMAN-Phosphoserine880 relationship: location_of CCO:B0066608 ! GRIA3_HUMAN-Phosphotyrosine887 relationship: location_of CCO:B0066627 ! GRM1_HUMAN-Phosphotyrosine1109 relationship: location_of CCO:B0066895 ! HRH1_HUMAN-Phosphoserine275 relationship: location_of CCO:B0067062 ! IGSF8_HUMAN-Phosphoserine12 relationship: location_of CCO:B0067075 ! IL2RG_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0067079 ! IL4RA_HUMAN-Phosphotyrosine631 relationship: location_of CCO:B0067081 ! IL7RA_HUMAN-Phosphotyrosine169 relationship: location_of CCO:B0067099 ! INAR1_HUMAN-Phosphotyrosine481 relationship: location_of CCO:B0067114 ! INGR1_HUMAN-Phosphoserine369 relationship: location_of CCO:B0067115 ! INGR2_HUMAN-Phosphoserine198 relationship: location_of CCO:B0067120 ! INSRR_HUMAN-Phosphotyrosine1145 relationship: location_of CCO:B0067159 ! ITA4_HUMAN-Phosphoserine1021 relationship: location_of CCO:B0067166 ! ITPR1_HUMAN-Phosphoserine1598 relationship: location_of CCO:B0067170 ! ITPR2_HUMAN-Phosphotyrosine2607 relationship: location_of CCO:B0067173 ! ITPR3_HUMAN-Phosphoserine1832 relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: location_of CCO:B0067267 ! KCAB2_HUMAN-Phosphotyrosine360 relationship: location_of CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 relationship: location_of CCO:B0067295 ! KCNH7_HUMAN-Phosphoserine353 relationship: location_of CCO:B0067366 ! KIT_HUMAN-Phosphotyrosine703 relationship: location_of CCO:B0067513 ! KTN1_HUMAN-Phosphoserine75 relationship: location_of CCO:B0067581 ! LAT_HUMAN-Phosphoserine84 relationship: location_of CCO:B0067594 ! LAX1_HUMAN-Phosphotyrosine373 relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: location_of CCO:B0067643 ! LGR6_HUMAN-Phosphoserine457 relationship: location_of CCO:B0067681 ! LIRB3_HUMAN-Phosphothreonine480 relationship: location_of CCO:B0067765 ! LPHN1_HUMAN-Phosphoserine1377 relationship: location_of CCO:B0067770 ! LPHN3_HUMAN-Phosphothreonine1445 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0067794 ! LTK_HUMAN-Phosphotyrosine672 relationship: location_of CCO:B0067845 ! MADD_HUMAN-Phosphoserine921 relationship: location_of CCO:B0068019 ! MAVS_HUMAN-Phosphothreonine398 relationship: location_of CCO:B0068058 ! MCL1_HUMAN-Phosphothreonine163 relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: location_of CCO:B0068070 ! MCTP2_HUMAN-Phosphoserine145 relationship: location_of CCO:B0068148 ! MERTK_HUMAN-Phosphotyrosine754 relationship: location_of CCO:B0068168 ! MIA3_HUMAN-Phosphoserine1906 relationship: location_of CCO:B0068634 ! NFAM1_HUMAN-Phosphotyrosine231 relationship: location_of CCO:B0068697 ! NFXL1_HUMAN-Phosphoserine107 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0068815 ! NPHN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0068836 ! NRG3_HUMAN-Phosphoserine119 relationship: location_of CCO:B0068876 ! NTAL_HUMAN-Phosphotyrosine233 relationship: location_of CCO:B0068879 ! NTRK1_HUMAN-Phosphotyrosine680 relationship: location_of CCO:B0068884 ! NTRK2_HUMAN-Phosphotyrosine706 relationship: location_of CCO:B0068888 ! NTRK3_HUMAN-Phosphotyrosine705 relationship: location_of CCO:B0068951 ! O52E8_HUMAN-Phosphoserine144 relationship: location_of CCO:B0068952 ! O56A3_HUMAN-Phosphotyrosine172 relationship: location_of CCO:B0068975 ! OPSD_HUMAN-Phosphoserine343 relationship: location_of CCO:B0068982 ! OR4S2_HUMAN-Phosphoserine227 relationship: location_of CCO:B0068996 ! OSMR_HUMAN-Phosphotyrosine837 relationship: location_of CCO:B0069007 ! OX1R_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0069014 ! P2RX5_HUMAN-Phosphotyrosine55 relationship: location_of CCO:B0069015 ! P2RX6_HUMAN-Phosphotyrosine54 relationship: location_of CCO:B0069016 ! P2RX7_HUMAN-Phosphotyrosine343 relationship: location_of CCO:B0069018 ! P2RY1_HUMAN-Phosphoserine354 relationship: location_of CCO:B0069020 ! P2RY4_HUMAN-Phosphoserine334 relationship: location_of CCO:B0069056 ! PAG1_HUMAN-Phosphotyrosine227 relationship: location_of CCO:B0069168 ! PDE3B_HUMAN-Phosphoserine442 relationship: location_of CCO:B0069237 ! PEX14_HUMAN-Phosphoserine335 relationship: location_of CCO:B0069291 ! PI2R_HUMAN-Cysteine methyl ester383 relationship: location_of CCO:B0069329 ! PKD1_HUMAN-Phosphoserine4288 relationship: location_of CCO:B0069380 ! PKP2_HUMAN-Phosphoserine329 relationship: location_of CCO:B0069421 ! PLXA1_HUMAN-Phosphotyrosine122 relationship: location_of CCO:B0069422 ! PLXA2_HUMAN-Phosphoserine1645 relationship: location_of CCO:B0069425 ! PLXA3_HUMAN-Phosphoserine1610 relationship: location_of CCO:B0069587 ! PTAD1_HUMAN-Phosphoserine114 relationship: location_of CCO:B0069640 ! PVRL2_HUMAN-Phosphoserine433 relationship: location_of CCO:B0069720 ! RAI3_HUMAN-Phosphotyrosine347 relationship: location_of CCO:B0069839 ! RCAS1_HUMAN-Phosphothreonine41 relationship: location_of CCO:B0070101 ! RN139_HUMAN-Phosphoserine625 relationship: location_of CCO:B0070125 ! ROBO1_HUMAN-Phosphotyrosine1038 relationship: location_of CCO:B0070139 ! RON_HUMAN-Phosphotyrosine1360 relationship: location_of CCO:B0070144 ! ROR2_HUMAN-Phosphotyrosine646 relationship: location_of CCO:B0070259 ! RTN1_HUMAN-Phosphoserine487 relationship: location_of CCO:B0070260 ! RTN2_HUMAN-Phosphoserine44 relationship: location_of CCO:B0070272 ! RYR2_HUMAN-Phosphoserine2806 relationship: location_of CCO:B0070277 ! S20A1_HUMAN-Phosphoserine265 relationship: location_of CCO:B0070283 ! S35B2_HUMAN-Phosphoserine427 relationship: location_of CCO:B0070285 ! S35E1_HUMAN-Phosphoserine363 relationship: location_of CCO:B0070287 ! S38A3_HUMAN-Phosphoserine54 relationship: location_of CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: location_of CCO:B0070370 ! SEM4D_HUMAN-Phosphoserine195 relationship: location_of CCO:B0070377 ! SERC3_HUMAN-Phosphoserine371 relationship: location_of CCO:B0070510 ! SHPS1_HUMAN-Phosphotyrosine495 relationship: location_of CCO:B0070556 ! SIT1_HUMAN-Phosphotyrosine127 relationship: location_of CCO:B0070575 ! SLAF1_HUMAN-Phosphotyrosine281 relationship: location_of CCO:B0070590 ! SMAD1_HUMAN-Phosphoserine463 relationship: location_of CCO:B0070605 ! SMAD5_HUMAN-Phosphoserine465 relationship: location_of CCO:B0070985 ! STX12_HUMAN-Phosphoserine142 relationship: location_of CCO:B0071220 ! TBC9B_HUMAN-Phosphoserine411 relationship: location_of CCO:B0071324 ! TEN1_HUMAN-Phosphoserine2580 relationship: location_of CCO:B0071350 ! TEX2_HUMAN-Phosphothreonine269 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071386 ! THS7A_HUMAN-Phosphotyrosine1341 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071420 ! TLR7_HUMAN-Phosphoserine1010 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 relationship: location_of CCO:B0071432 ! TMM22_HUMAN-Phosphoserine409 relationship: location_of CCO:B0071433 ! TMM51_HUMAN-Phosphoserine115 relationship: location_of CCO:B0071442 ! TNR11_HUMAN-Phosphoserine463 relationship: location_of CCO:B0071490 ! TR10A_HUMAN-Phosphoserine83 relationship: location_of CCO:B0071584 ! TRPC6_HUMAN-Phosphoserine815 relationship: location_of CCO:B0071644 ! TYOBP_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0071646 ! TYRO3_HUMAN-Phosphotyrosine686 relationship: location_of CCO:B0071734 ! UNC5C_HUMAN-Phosphotyrosine568 relationship: location_of CCO:B0071735 ! UNC5D_HUMAN-Phosphothreonine210 relationship: location_of CCO:B0071774 ! VAPB_HUMAN-Phosphoserine159 relationship: location_of CCO:B0071808 ! VIPR1_HUMAN-Phosphoserine449 relationship: location_of CCO:B0071842 ! WFS1_HUMAN-Phosphoserine32 relationship: location_of CCO:B0071899 ! YA043_HUMAN-Phosphoserine14 [Term] id: CCO:C0000770 name: inaD signaling complex namespace: cellular_component def: "A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD." [FB:FBrf0105321, GOC:hb, PMID:9010208] synonym: "inaD signalling complex" EXACT [] xref: GO:0016027 is_a: CCO:C0000899 ! extrinsic to plasma membrane is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000771 ! rhabdomere [Term] id: CCO:C0000771 name: rhabdomere namespace: cellular_component def: "The specialized microvillar organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction." [GOC:hb, PMID:8646774] subset: goslim_pir xref: GO:0016028 is_a: CCO:C0001706 ! cell projection [Term] id: CCO:C0000772 name: subrhabdomeral cisterna namespace: cellular_component def: "A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase." [PMID:11707492, PMID:8646774] synonym: "SMC" RELATED [] synonym: "submicrovillar cisterna" EXACT [PMID:11707492] xref: GO:0016029 is_a: CCO:C0001376 ! organelle subcompartment relationship: part_of CCO:C0000371 ! smooth endoplasmic reticulum relationship: part_of CCO:C0000771 ! rhabdomere [Term] id: CCO:C0000773 name: zeta DNA polymerase complex namespace: cellular_component def: "A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer." [PMID:16631579, PMID:16971464] xref: GO:0016035 is_a: CCO:C0001651 ! DNA polymerase complex is_a: CCO:C0001865 ! intracellular organelle part [Term] id: CCO:C0000774 name: procollagen-proline, 2-oxoglutarate-4-dioxygenase complex namespace: cellular_component def: "An enzyme complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate." [EC:1.14.11.2] xref: GO:0016222 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000775 name: inclusion body namespace: cellular_component def: "Intracellular foci at which aggregated proteins have been sequestered." [PMID:11121744] xref: GO:0016234 is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000776 name: aggresome namespace: cellular_component def: "An inclusion body resulting from dynein-dependent retrograde transport of an aggregated protein on microtubules." [PMID:11121744] xref: GO:0016235 is_a: CCO:C0000775 ! inclusion body relationship: location_of CCO:B0054980 ! CLUS_HUMAN [Term] id: CCO:C0000777 name: prefoldin complex namespace: cellular_component def: "A multisubunit chaperone that acts to delivers unfolded proteins to cytosolic chaperonin. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits." [GOC:jl, UniProtKB:O15212] subset: gosubset_prok synonym: "GIM complex" NARROW [] xref: GO:0016272 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0001420 ! PFD1_HUMAN relationship: location_of CCO:B0029133 ! PFD2_HUMAN relationship: location_of CCO:B0038197 ! PFD3_HUMAN relationship: location_of CCO:B0058416 ! PFD5_HUMAN relationship: location_of CCO:B0063098 ! PFD6_HUMAN relationship: location_of CCO:B0063103 ! PFD4_HUMAN relationship: location_of CCO:B0063105 ! Q9C083_HUMAN relationship: location_of CCO:B0063112 ! UXT_HUMAN relationship: location_of CCO:B0063142 ! PDRG1_HUMAN relationship: location_of CCO:B0070096 ! RMP_HUMAN-Phosphothreonine242 [Term] id: CCO:C0000778 name: eukaryotic translation initiation factor 4F complex namespace: cellular_component def: "The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome." [GOC:hb, UniProtKB:P41110] synonym: "eIF-4F" EXACT [] synonym: "eukaryotic translation initiation factor 4 complex" BROAD [] xref: GO:0016281 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0005679 ! IF4A1_HUMAN relationship: location_of CCO:B0005728 ! IF4A2_HUMAN relationship: location_of CCO:B0012333 ! IF4G2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0016186 ! IF4E_HUMAN relationship: location_of CCO:B0052434 ! IF4B_HUMAN-Phosphoserine422 relationship: location_of CCO:B0054565 ! 4EBP3_HUMAN relationship: location_of CCO:B0067036 ! IF4G1_HUMAN-Phosphoserine1210 relationship: location_of CCO:B0067041 ! IF4G3_HUMAN-Phosphoserine232 relationship: location_of CCO:B0067049 ! IF4H_HUMAN-Phosphoserine193 [Term] id: CCO:C0000779 name: eukaryotic 43S preinitiation complex namespace: cellular_component def: "A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA." [GOC:hjd, PMID:15145049] synonym: "eukaryotic 43S pre-initiation complex" EXACT [] xref: GO:0016282 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000780 name: basolateral plasma membrane namespace: cellular_component def: "Part of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis." [GOC:go_curators] xref: GO:0016323 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0002110 ! CADM1_HUMAN relationship: location_of CCO:B0005549 ! MEG10_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0005706 ! M4K2_HUMAN relationship: location_of CCO:B0005906 ! ERBB4_HUMAN relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0031296 ! AT1B1_HUMAN-Phosphotyrosine101 relationship: location_of CCO:B0041523 ! ANK1_HUMAN relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0054933 ! IL6RA_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055145 ! ENPP1_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0058057 ! AQP3_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 [Term] id: CCO:C0000781 name: apical plasma membrane namespace: cellular_component def: "Part of the plasma membrane at the apical end of the cell." [GOC:curators] xref: GO:0016324 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0006345 ! CATB_HUMAN relationship: location_of CCO:B0010381 ! 4F2_HUMAN-Phosphothreonine5 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0054485 ! AT8B1_HUMAN relationship: location_of CCO:B0054511 ! AKA7A_HUMAN relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0055131 ! MAL_HUMAN relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055781 ! AMPE_HUMAN relationship: location_of CCO:B0057919 ! PKHD1_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058577 ! PCD24_HUMAN relationship: location_of CCO:B0058896 ! DUOX2_HUMAN relationship: location_of CCO:B0058897 ! DUOX1_HUMAN relationship: location_of CCO:B0062844 ! AQP5_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0064565 ! CSPG4_HUMAN-Phosphothreonine21 relationship: location_of CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0067093 ! INADL_HUMAN-Phosphoserine455 relationship: location_of CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068709 ! NHERF_HUMAN-Phosphoserine288 relationship: location_of CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 relationship: part_of CCO:C0001896 ! apical part of cell [Term] id: CCO:C0000782 name: apicolateral plasma membrane namespace: cellular_component def: "The apical end of the lateral plasma membrane of epithelial cells." [GOC:hb] subset: gosubset_prok xref: GO:0016327 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0054549 ! FZD6_HUMAN [Term] id: CCO:C0000783 name: lateral plasma membrane namespace: cellular_component def: "The membranes on the sides of epithelial cells which lie at the interface of adjacent cells." [GOC:hb] xref: GO:0016328 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0001367 ! AXN1_HUMAN relationship: location_of CCO:B0010567 ! APC_HUMAN-Phosphoserine1038 relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0054511 ! AKA7A_HUMAN relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN [Term] id: CCO:C0000784 name: catenin complex namespace: cellular_component def: "Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton." [ISBN:0198599323] xref: GO:0016342 is_a: CCO:C0000899 ! extrinsic to plasma membrane is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0031540 ! APC2_HUMAN [Term] id: CCO:C0000785 name: nuclear matrix namespace: cellular_component def: "The dense fibrillar network lying on the inner side of the nuclear membrane." [ISBN:0582227089] xref: GO:0016363 is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001451 ! YETS4_HUMAN relationship: location_of CCO:B0001930 ! MAEA_HUMAN relationship: location_of CCO:B0002148 ! CHM1A_HUMAN relationship: location_of CCO:B0002249 ! RUVB1_HUMAN relationship: location_of CCO:B0005364 ! RUVB2_HUMAN relationship: location_of CCO:B0005402 ! PIAS4_HUMAN relationship: location_of CCO:B0005632 ! MYB_HUMAN relationship: location_of CCO:B0010485 ! AKAP8_HUMAN-Phosphoserine339 relationship: location_of CCO:B0010721 ! ATX7_HUMAN-Phosphothreonine854 relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0011580 ! DPOLA_HUMAN-Phosphoserine186 relationship: location_of CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0014029 ! SFPQ_HUMAN-Omega-N-methylated arginine25 relationship: location_of CCO:B0014076 ! SMC3_HUMAN-Phosphoserine787 relationship: location_of CCO:B0014560 ! TYY1_HUMAN-Phosphoserine184 relationship: location_of CCO:B0017947 ! PHF5A_HUMAN relationship: location_of CCO:B0018465 ! ZN326_HUMAN relationship: location_of CCO:B0033320 ! COF1_HUMAN relationship: location_of CCO:B0034678 ! COF2_HUMAN-Phosphoserine3 relationship: location_of CCO:B0035773 ! TGFI1_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0039404 ! DNM3A_HUMAN-Phosphoserine105 relationship: location_of CCO:B0041169 ! P53_HUMAN-Phosphoserine9 relationship: location_of CCO:B0048315 ! MATR3_HUMAN-Phosphoserine206 relationship: location_of CCO:B0049689 ! ATX3_HUMAN relationship: location_of CCO:B0054583 ! KIN17_HUMAN relationship: location_of CCO:B0055887 ! ERCC8_HUMAN relationship: location_of CCO:B0057588 ! GMCLL_HUMAN relationship: location_of CCO:B0058017 ! PSPC1_HUMAN relationship: location_of CCO:B0058230 ! GMCL1_HUMAN relationship: location_of CCO:B0058641 ! ZN350_HUMAN relationship: location_of CCO:B0059143 ! NUFP1_HUMAN relationship: location_of CCO:B0063661 ! ATX1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0064605 ! CXXC1_HUMAN-Phosphoserine224 relationship: location_of CCO:B0065574 ! AKP8L_HUMAN-Phosphoserine297 relationship: location_of CCO:B0070650 ! SMRCD_HUMAN-Phosphoserine34 relationship: location_of CCO:B0070840 ! SPTN4_HUMAN-Phosphothreonine2112 relationship: location_of CCO:B0071383 ! THOC1_HUMAN-Phosphoserine2 relationship: part_of CCO:C0001373 ! nuclear lumen [Term] id: CCO:C0000786 name: RNA-induced silencing complex namespace: cellular_component def: "A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation." [PMID:10749213, PMID:15145345] synonym: "RISC complex" EXACT [] xref: GO:0016442 is_a: CCO:C0001205 ! RNAi effector complex relationship: location_of CCO:B0070680 ! SND1_HUMAN-Phosphothreonine429 [Term] id: CCO:C0000787 name: X chromosome located dosage compensation complex, transcription activating namespace: cellular_component def: "An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome." [GOC:ma, GOC:mtg_sensu] synonym: "dosage compensation complex (sensu Insecta)" EXACT [] xref: GO:0016456 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001953 ! dosage compensation complex relationship: part_of CCO:C0000132 ! X chromosome [Term] id: CCO:C0000788 name: myosin complex namespace: cellular_component def: "A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, ISBN:96235764] xref: GO:0016459 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0013066 ! MYH14_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0019193 ! MYH9_HUMAN relationship: location_of CCO:B0031117 ! Q4LE74_HUMAN relationship: location_of CCO:B0031342 ! MYO16_HUMAN-Phosphotyrosine1432 relationship: location_of CCO:B0031823 ! MYO3B_HUMAN relationship: location_of CCO:B0032855 ! MYH10_HUMAN-Phosphothreonine1960 relationship: location_of CCO:B0035225 ! MYH1_HUMAN-Phosphothreonine1933 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0040141 ! B0I1T6_HUMAN relationship: location_of CCO:B0040367 ! MYO1F_HUMAN relationship: location_of CCO:B0054982 ! MLRV_HUMAN relationship: location_of CCO:B0059252 ! Q9UNJ2_HUMAN relationship: location_of CCO:B0062812 ! DYL2_HUMAN relationship: location_of CCO:B0063055 ! MYO1D_HUMAN relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0063101 ! MYO1B_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0063410 ! MYO15_HUMAN relationship: location_of CCO:B0068290 ! MRLC3_HUMAN-Phosphothreonine18 relationship: location_of CCO:B0068346 ! MY18A_HUMAN-Phosphoserine2020 relationship: location_of CCO:B0068376 ! MYL6_HUMAN-Phosphotyrosine29 relationship: location_of CCO:B0068380 ! MYL9_HUMAN-Phosphoserine29 relationship: location_of CCO:B0068390 ! MYO10_HUMAN-Phosphoserine968 relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0000789 name: myosin II complex namespace: cellular_component def: "A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, ISBN:96235764] synonym: "conventional myosin" RELATED [] xref: GO:0016460 is_a: CCO:C0000788 ! myosin complex [Term] id: CCO:C0000790 name: unconventional myosin complex namespace: cellular_component def: "A portmanteau term for myosins other than myosin II." [GOC:ma] comment: Note that this term is retained because it is widely used by biologists. synonym: "non-muscle myosin" RELATED [] xref: GO:0005860 xref: GO:0016461 is_a: CCO:C0000788 ! myosin complex relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0040367 ! MYO1F_HUMAN relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0068376 ! MYL6_HUMAN-Phosphotyrosine29 [Term] id: CCO:C0000791 name: chaperonin ATPase complex namespace: cellular_component def: "Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts." [EC:3.6.4.9] xref: GO:0016465 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0000792 name: proton-transporting two-sector ATPase complex namespace: cellular_component def: "A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible." [GOC:mah, ISBN:0716743663, PMID:16691483] subset: goslim_pir subset: gosubset_prok synonym: "hydrogen-transporting two-sector ATPase complex" EXACT [] synonym: "vacuolar hydrogen-transporting ATPase" RELATED [] xref: GO:0016469 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: location_of CCO:B0021842 ! VATE1_HUMAN relationship: location_of CCO:B0028140 ! VATL_HUMAN relationship: location_of CCO:B0063396 ! VAS1_HUMAN relationship: location_of CCO:B0065764 ! ATPO_HUMAN-N6-acetyllysine176 relationship: location_of CCO:B0071772 ! VA0D1_HUMAN-Phosphotyrosine270 relationship: location_of CCO:B0071785 ! VATC1_HUMAN-N-acetylthreonine2 [Term] id: CCO:C0000793 name: vacuolar proton-transporting V-type ATPase complex namespace: cellular_component def: "A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen." [GOC:mah, ISBN:0716743663, PMID:16449553] comment: See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'. subset: gosubset_prok synonym: "vacuolar hydrogen-translocating V-type ATPase complex" EXACT [] xref: GO:0016471 is_a: CCO:C0001546 ! proton-transporting V-type ATPase complex is_a: CCO:C0001856 ! vacuolar part relationship: location_of CCO:B0071772 ! VA0D1_HUMAN-Phosphotyrosine270 relationship: part_of CCO:C0000356 ! vacuolar membrane [Term] id: CCO:C0000794 name: sodium ion-transporting two-sector ATPase complex namespace: cellular_component def: "A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis." [GOC:mah, PMID:14656431] subset: goslim_pir synonym: "sodium-transporting two-sector ATPase complex" EXACT [] xref: GO:0016472 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000795 name: sodium ion-transporting F-type ATPase complex namespace: cellular_component def: "A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism." [GOC:mah, PMID:14656431] synonym: "sodium-translocating F-type ATPase complex" EXACT [] xref: GO:0016473 is_a: CCO:C0000794 ! sodium ion-transporting two-sector ATPase complex [Term] id: CCO:C0000796 name: sodium ion-transporting V-type ATPase complex namespace: cellular_component def: "A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis." [GOC:mah, PMID:15802565] synonym: "sodium-translocating V-type ATPase complex" EXACT [] xref: GO:0016474 is_a: CCO:C0000794 ! sodium ion-transporting two-sector ATPase complex [Term] id: CCO:C0000797 name: fatty acid beta-oxidation multienzyme complex namespace: cellular_component def: "A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix." [GOC:ma] synonym: "trifunctional enzyme" RELATED [] xref: GO:0016507 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0065977 ! ECHA_HUMAN-N6-acetyllysine728 relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000798 name: core-binding factor complex namespace: cellular_component def: "A heterodimer with alpha- and beta-subunits that binds the core site 5'-PYGPYGGT-3' of several enhancers and promoters; the beta-subunit enhances the DNA binding of the alpha-subunit." [UniProtKB:Q08024] xref: GO:0016513 is_a: CCO:C0000272 ! transcription factor complex [Term] id: CCO:C0000799 name: SWI/SNF complex namespace: cellular_component def: "Any of a family of protein complexes that regulate transcription by remodeling chromatin. Swi/Snf complexes comprise nine or more proteins, including both conserved (core) and nonconserved components; the Swi2/Snf2 ATPase is one of the core components." [GOC:mah, PMID:12672490] xref: GO:0016514 is_a: CCO:C0000806 ! chromatin remodeling complex relationship: location_of CCO:B0001732 ! SNF5_HUMAN relationship: location_of CCO:B0005417 ! SMRC2_HUMAN relationship: location_of CCO:B0005418 ! SMRC1_HUMAN relationship: location_of CCO:B0010600 ! ARI1A_HUMAN-Phosphoserine1755 relationship: location_of CCO:B0016782 ! ACL6B_HUMAN relationship: location_of CCO:B0054688 ! NCTR1_HUMAN relationship: location_of CCO:B0056941 ! SMRD3_HUMAN relationship: location_of CCO:B0063573 ! ARI1B_HUMAN-Phosphoserine1559 [Term] id: CCO:C0000800 name: interleukin-4 receptor complex namespace: cellular_component def: "Complexes that bind interleukin-4; consist of alpha, beta, and gamma chains and exist in three forms, one containing extracellular transmembrane and cytoplasmic domains, one lacking the cytoplasmic domain and a third that is secreted." [UniProtKB:P16382] xref: GO:0016516 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000801 name: sarcoplasm namespace: cellular_component def: "The cytoplasm of a muscle fiber; includes the sarcoplasmic reticulum." [ISBN:0198547684] xref: GO:0016528 is_a: CCO:C0000324 ! cytoplasm [Term] id: CCO:C0000802 name: sarcoplasmic reticulum namespace: cellular_component def: "A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle fiber; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage." [GOC:mtg_muscle, ISBN:0124325653, ISBN:0198547684] comment: See also the cellular component terms 'sarcoplasm ; GO:0016528', 'nuclear envelope ; GO:0005635' and 'endoplasmic reticulum ; GO:0005783'. xref: GO:0008221 xref: GO:0016529 is_a: CCO:C0000364 ! endoplasmic reticulum relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0041523 ! ANK1_HUMAN relationship: location_of CCO:B0055155 ! S10A1_HUMAN relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0063298 ! PPLA_HUMAN relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: part_of CCO:C0000801 ! sarcoplasm [Term] id: CCO:C0000803 name: cyclin-dependent protein kinase 5 activator complex namespace: cellular_component def: "A protein complex that activates cyclin-dependent kinase 5; composed of regulatory and catalytic subunits." [UniProtKB:Q62938] xref: GO:0016533 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001751 ! CD5R2_HUMAN relationship: location_of CCO:B0001802 ! CD5R1_HUMAN [Term] id: CCO:C0000804 name: Sin3 complex namespace: cellular_component def: "A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins." [PMID:10589671, PMID:11743021, PMID:12865422] xref: GO:0016580 is_a: CCO:C0000008 ! histone deacetylase complex relationship: location_of CCO:B0013984 ! SDS3_HUMAN-Phosphothreonine55 [Term] id: CCO:C0000805 name: NuRD complex namespace: cellular_component def: "An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins." [PMID:10589671, PMID:11743021, PMID:17289569] synonym: "Mi-2 complex" EXACT [] synonym: "NRD complex" EXACT [] synonym: "nucleosome remodeling and histone deacetylation complex" EXACT [] synonym: "SHREC complex" EXACT [] xref: GO:0016581 is_a: CCO:C0000008 ! histone deacetylase complex relationship: location_of CCO:B0001727 ! RBBP4_HUMAN relationship: location_of CCO:B0001980 ! DP13B_HUMAN relationship: location_of CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: location_of CCO:B0013353 ! P66A_HUMAN-Phosphoserine114 relationship: location_of CCO:B0068312 ! MTA2_HUMAN-Phosphoserine57 [Term] id: CCO:C0000806 name: chromatin remodeling complex namespace: cellular_component def: "Any complex that mediates dynamic changes in eukaryotic chromatin." [GOC:mah] subset: goslim_pir synonym: "chromatin remodelling complex" EXACT [] synonym: "nucleosome remodeling complex" EXACT [] xref: GO:0005679 xref: GO:0016585 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0005268 ! ASF1A_HUMAN relationship: location_of CCO:B0005415 ! SMRD1_HUMAN relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0068312 ! MTA2_HUMAN-Phosphoserine57 relationship: location_of CCO:B0070619 ! SMCA1_HUMAN-Phosphotyrosine954 relationship: location_of CCO:B0070643 ! SMCA5_HUMAN-Phosphoserine755 [Term] id: CCO:C0000807 name: RSC complex namespace: cellular_component def: "A protein complex similar to, but more abundant than, the Swi/Snf complex. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining." [PMID:11937489, PMID:12672490, PMID:15870268, PMID:8980231] xref: GO:0016586 is_a: CCO:C0000806 ! chromatin remodeling complex [Term] id: CCO:C0000808 name: ISW1 complex namespace: cellular_component def: "A protein complex that contains an ISWI-family ATPase such as Saccharomyces Isw1p, and acts to modify chromatin structure." [GOC:mah, PMID:15020051] xref: GO:0016587 is_a: CCO:C0001107 ! ISWI complex [Term] id: CCO:C0000809 name: NURF complex namespace: cellular_component def: "A four subunit ISWI-containing protein complex that facilitates nucleosome mobility and transcriptional activation in an ATP-dependent manner. In contrast to other chromatin remodeling complexes, the ATPase activity of NURF requires nucleosomes rather than free DNA or histones." [GOC:bf, PMID:10779516, PMID:11279013] synonym: "nucleosome remodeling factor complex" EXACT [] xref: GO:0016589 is_a: CCO:C0001107 ! ISWI complex [Term] id: CCO:C0000810 name: ACF complex namespace: cellular_component def: "A chromatin-remodeling complex that catalyzes the ATP-dependent assembly of periodic nucleosome arrays. In Drosophila, the complex comprises ACF1 and ISWI." [GOC:bf, PMID:12192034] synonym: "ATP-utilizing chromatin assembly and remodeling factor complex" EXACT [] xref: GO:0016590 is_a: CCO:C0000281 ! chromatin assembly complex [Term] id: CCO:C0000811 name: DNA-directed RNA polymerase II, holoenzyme namespace: cellular_component def: "Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA." [GOC:jl, http://en.wikipedia.org/, PMID:15196470] subset: goslim_pir xref: GO:0016591 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0005398 ! ELP1_HUMAN relationship: location_of CCO:B0011752 ! ERCC5_HUMAN-Phosphoserine384 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0048582 ! ELP2_HUMAN relationship: location_of CCO:B0065043 ! ELP3_HUMAN-Phosphotyrosine202 relationship: location_of CCO:B0065045 ! ELP4_HUMAN-Phosphoserine42 [Term] id: CCO:C0000812 name: Srb-mediator complex namespace: cellular_component def: "A multiprotein transcriptional mediator complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and is essential for transcription of most protein-coding genes. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Mammalian Srb-mediator complexes include homologs of yeast Srb and Med proteins." [PMID:16168358, PMID:9396788] synonym: "CDK8-containing TRAP/mediator complex" EXACT [] synonym: "L mediator complex" EXACT [] xref: GO:0016592 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0005781 ! MED20_HUMAN [Term] id: CCO:C0000813 name: Cdc73/Paf1 complex namespace: cellular_component def: "A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Hpr1p, Ccr4p, Ctr9p, Rtf1p, and Leo1p." [PMID:11884586] xref: GO:0016593 is_a: CCO:C0000523 ! transcription elongation factor complex relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0000815 name: flotillin complex namespace: cellular_component def: "A heteromeric complex of flotillin 1, flotillin 2, caveolin 1 and caveolin 2 within the caveolar membrane." [UniProtKB:O61491] comment: See also the cellular component term 'caveolar membrane ; GO:0016599'. xref: GO:0016600 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0012863 ! MDC1_HUMAN-Phosphothreonine523 relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 relationship: part_of CCO:C0000458 ! caveola [Term] id: CCO:C0000816 name: CCAAT-binding factor complex namespace: cellular_component def: "A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; in Saccharomyces it activates the transcription of genes in response to growth in a nonfermentable carbon source; consists of four known subunits: HAP2, HAP3, HAP4 and HAP5." [PMID:7828851] xref: GO:0016602 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0001770 ! NFYC_HUMAN relationship: location_of CCO:B0005382 ! NFYB_HUMAN relationship: location_of CCO:B0005384 ! NFYA_HUMAN relationship: location_of CCO:B0017118 ! ING2_HUMAN [Term] id: CCO:C0000817 name: nuclear body namespace: cellular_component def: "Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins." [GOC:ma, PMID:10330182] xref: GO:0016604 is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0020553 ! RING1_HUMAN relationship: location_of CCO:B0062979 ! GEMI5_HUMAN relationship: location_of CCO:B0063415 ! GEMI7_HUMAN relationship: location_of CCO:B0066804 ! HIPK2_HUMAN-Phosphotyrosine361 relationship: location_of CCO:B0070190 ! RREB1_HUMAN-Phosphothreonine1315 [Term] id: CCO:C0000818 name: PML body namespace: cellular_component def: "A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection." [GOC:ma, PMID:10944585] synonym: "ND10" EXACT [] synonym: "nuclear dot" RELATED [] xref: GO:0016605 is_a: CCO:C0000817 ! nuclear body relationship: location_of CCO:B0001459 ! CHK2_HUMAN relationship: location_of CCO:B0001562 ! RFA1_HUMAN relationship: location_of CCO:B0001696 ! UBC9_HUMAN relationship: location_of CCO:B0001721 ! RAD51_HUMAN relationship: location_of CCO:B0001753 ! TOP3A_HUMAN relationship: location_of CCO:B0010803 ! BLM_HUMAN-Phosphoserine499 relationship: location_of CCO:B0013572 ! PML_HUMAN-Phosphoserine8 relationship: location_of CCO:B0013804 ! RB_HUMAN-Phosphothreonine826 relationship: location_of CCO:B0024552 ! O60424_HUMAN relationship: location_of CCO:B0048217 ! DAXX_HUMAN-Phosphoserine178 relationship: location_of CCO:B0055743 ! ZBT16_HUMAN relationship: location_of CCO:B0055963 ! MORC3_HUMAN relationship: location_of CCO:B0057245 ! RIP_HUMAN relationship: location_of CCO:B0058159 ! ISG20_HUMAN relationship: location_of CCO:B0064979 ! ELF4_HUMAN-Phosphothreonine643 relationship: location_of CCO:B0067775 ! LRCH4_HUMAN-Phosphoserine183 relationship: location_of CCO:B0070418 ! SFRS2_HUMAN-Phosphotyrosine23 relationship: location_of CCO:B0070768 ! SP100_HUMAN-Phosphoserine459 relationship: location_of CCO:B0070840 ! SPTN4_HUMAN-Phosphothreonine2112 [Term] id: CCO:C0000819 name: Lands namespace: cellular_component def: "A class of nuclear body (Lands = LYSP100-associated nuclear domains); they are globular, electron-dense structures that may traffic between the nucleus and cytoplasm; they react against SP140 auto-antibodies." [UniProtKB:Q13342] xref: GO:0016606 is_a: CCO:C0000817 ! nuclear body [Term] id: CCO:C0000820 name: nuclear speck namespace: cellular_component def: "A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy." [http://www.cellnucleus.com/] synonym: "nuclear speckle" EXACT [] synonym: "nuclear speckles" EXACT [] synonym: "speckle domain" NARROW [] synonym: "speckle focus" RELATED [] synonym: "splicing speckle" EXACT [] xref: GO:0016607 is_a: CCO:C0000817 ! nuclear body relationship: location_of CCO:B0002065 ! CDC5L_HUMAN relationship: location_of CCO:B0005321 ! PIAS2_HUMAN relationship: location_of CCO:B0005593 ! CRNL1_HUMAN relationship: location_of CCO:B0005613 ! SET1A_HUMAN relationship: location_of CCO:B0006001 ! RFWD2_HUMAN relationship: location_of CCO:B0011004 ! CCNL1_HUMAN-Phosphoserine65 relationship: location_of CCO:B0011473 ! DDX3X_HUMAN-Phosphoserine74 relationship: location_of CCO:B0011622 ! EAF1_HUMAN-Phosphoserine158 relationship: location_of CCO:B0012801 ! MBD1_HUMAN-Phosphoserine295 relationship: location_of CCO:B0013266 ! NUAK2_HUMAN-Phosphoserine377 relationship: location_of CCO:B0013353 ! P66A_HUMAN-Phosphoserine114 relationship: location_of CCO:B0013509 ! PIAS1_HUMAN-Phosphoserine483 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0014041 ! SFRS1_HUMAN-Phosphoserine238 relationship: location_of CCO:B0014272 ! SUMO1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0018461 ! PIAS3_HUMAN relationship: location_of CCO:B0020282 ! SRY_HUMAN relationship: location_of CCO:B0020553 ! RING1_HUMAN relationship: location_of CCO:B0034353 ! SET1B_HUMAN relationship: location_of CCO:B0034614 ! CCNL2_HUMAN-Phosphoserine351 relationship: location_of CCO:B0035471 ! PRP8_HUMAN-Phosphothreonine1318 relationship: location_of CCO:B0043283 ! GLIS2_HUMAN-Phosphoserine245 relationship: location_of CCO:B0048327 ! MLL5_HUMAN-Phosphoserine1405 relationship: location_of CCO:B0052736 ! SF3B1_HUMAN-Phosphothreonine223 relationship: location_of CCO:B0055529 ! ELL_HUMAN relationship: location_of CCO:B0055743 ! ZBT16_HUMAN relationship: location_of CCO:B0057409 ! MAML2_HUMAN relationship: location_of CCO:B0058068 ! MAML1_HUMAN relationship: location_of CCO:B0058183 ! EAF2_HUMAN relationship: location_of CCO:B0058242 ! MAML3_HUMAN relationship: location_of CCO:B0059227 ! ZMIZ1_HUMAN relationship: location_of CCO:B0059339 ! CBY1_HUMAN relationship: location_of CCO:B0063342 ! ATPF2_HUMAN relationship: location_of CCO:B0064360 ! CIR_HUMAN-Phosphoserine202 relationship: location_of CCO:B0064605 ! CXXC1_HUMAN-Phosphoserine224 relationship: location_of CCO:B0066315 ! FUSIP_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0069454 ! PP1R8_HUMAN-Phosphotyrosine264 relationship: location_of CCO:B0069483 ! PR40A_HUMAN-Phosphoserine933 relationship: location_of CCO:B0069558 ! PRPF3_HUMAN-Phosphoserine619 relationship: location_of CCO:B0069815 ! RBM39_HUMAN-Phosphoserine127 relationship: location_of CCO:B0070116 ! RNPS1_HUMAN-Phosphoserine287 relationship: location_of CCO:B0070190 ! RREB1_HUMAN-Phosphothreonine1315 relationship: location_of CCO:B0070394 ! SF17A_HUMAN-Phosphoserine633 relationship: location_of CCO:B0070734 ! SON_HUMAN-Phosphoserine1784 relationship: location_of CCO:B0070797 ! SPF30_HUMAN-Phosphoserine201 relationship: location_of CCO:B0071383 ! THOC1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0071928 ! YLPM1_HUMAN-Phosphoserine634 relationship: location_of CCO:B0072196 ! ZN638_HUMAN-Phosphoserine605 [Term] id: CCO:C0000821 name: nitrogenase complex namespace: cellular_component def: "An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen." [EC:1.18.6.1, MetaCyc:CPLX-186, MetaCyc:CPLX-525] subset: goslim_pir subset: gosubset_prok xref: GO:0016610 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000822 name: iron-iron nitrogenase complex namespace: cellular_component def: "An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen." [EC:1.18.6.1, GOC:jl, PMID:11848850] comment: Note that it is not established whether the nitrogenase exists in vivo in a specific particle or whether the nitrogenase proteins are bound nonspecifically to the membranes of some cells. subset: gosubset_prok xref: GO:0016611 is_a: CCO:C0000821 ! nitrogenase complex [Term] id: CCO:C0000823 name: molybdenum-iron nitrogenase complex namespace: cellular_component def: "An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer." [EC:1.18.6.1] subset: gosubset_prok synonym: "molybdenum-iron nitrogenase activity" RELATED [] xref: GO:0016612 is_a: CCO:C0000821 ! nitrogenase complex [Term] id: CCO:C0000824 name: vanadium-iron nitrogenase complex namespace: cellular_component def: "An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer." [EC:1.18.6.1, PMID:3474027] subset: gosubset_prok synonym: "vanadium-iron nitrogenase activity" RELATED [] xref: GO:0016613 is_a: CCO:C0000821 ! nitrogenase complex [Term] id: CCO:C0000825 name: follicle-stimulating hormone complex namespace: cellular_component def: "A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity." [ISBN:0198547684] xref: GO:0016914 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part [Term] id: CCO:C0000826 name: glycine-gated chloride channel complex namespace: cellular_component def: "A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts." [GOC:mah] xref: GO:0016935 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000827 name: kinesin I complex namespace: cellular_component def: "A complex of two kinesin heavy chains and two kinesin light chains." [http://www.csfic.mi.cnr.it/centro/lines/8/ric.html] xref: GO:0016938 is_a: CCO:C0000431 ! kinesin complex [Term] id: CCO:C0000828 name: kinesin II complex namespace: cellular_component def: "A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes." [http://www.csfic.mi.cnr.it/centro/lines/8/ric.html] xref: GO:0016939 is_a: CCO:C0000431 ! kinesin complex relationship: location_of CCO:B0058104 ! KIFA3_HUMAN [Term] id: CCO:C0000829 name: insulin-like growth factor binding protein complex namespace: cellular_component def: "A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development." [GOC:jl] subset: goslim_pir synonym: "IGF binding protein complex" EXACT [] xref: GO:0016942 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0043821 ! IGF1B_HUMAN relationship: location_of CCO:B0055094 ! IBP3_HUMAN relationship: location_of CCO:B0055174 ! IBP5_HUMAN relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0000830 name: myosin phosphatase complex namespace: cellular_component def: "An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin." [EC:3.1.3.16] xref: GO:0017023 is_a: CCO:C0000541 ! protein serine/threonine phosphatase complex [Term] id: CCO:C0000831 name: transcriptional repressor complex namespace: cellular_component def: "A protein complex that possesses activity that prevents or downregulates transcription." [GOC:mah] subset: goslim_pir xref: GO:0017053 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0005416 ! SMCE1_HUMAN relationship: location_of CCO:B0005417 ! SMRC2_HUMAN relationship: location_of CCO:B0005850 ! GLI3_HUMAN relationship: location_of CCO:B0055743 ! ZBT16_HUMAN relationship: location_of CCO:B0057269 ! JAZF1_HUMAN relationship: location_of CCO:B0058641 ! ZN350_HUMAN relationship: location_of CCO:B0058934 ! RNF12_HUMAN relationship: location_of CCO:B0064702 ! DDX20_HUMAN-Phosphoserine656 relationship: location_of CCO:B0069253 ! PHF12_HUMAN-Phosphothreonine671 [Term] id: CCO:C0000832 name: negative cofactor 2 complex namespace: cellular_component def: "A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini." [PMID:15574413] xref: GO:0017054 is_a: CCO:C0000831 ! transcriptional repressor complex [Term] id: CCO:C0000833 name: serine C-palmitoyltransferase complex namespace: cellular_component def: "An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine." [EC:2.3.1.50] xref: GO:0017059 is_a: CCO:C0001146 ! palmitoyltransferase complex [Term] id: CCO:C0000834 name: intracellular cyclic nucleotide activated cation channel complex namespace: cellular_component def: "A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts." [GOC:mah] xref: GO:0017071 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000835 name: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex namespace: cellular_component def: "A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamin diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate." [EC:1.2.4.4] synonym: "BCADH" EXACT [] synonym: "branched-chain alpha-ketoacid dehydrogenase complex" EXACT [] xref: GO:0017086 xref: GO:0031212 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001848 ! mitochondrial part relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000836 name: mitochondrial processing peptidase complex namespace: cellular_component def: "This enzyme complex catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion." [EC:3.4.24.64] xref: GO:0017087 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001848 ! mitochondrial part relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000837 name: meprin A complex namespace: cellular_component def: "An enzyme complex that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues." [EC:3.4.24.18] xref: GO:0017090 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000838 name: aminoacyl-tRNA synthetase multienzyme complex namespace: cellular_component def: "A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates." [GOC:jl, PMID:16169847] synonym: "aminoacyl-tRNA synthetase complex" EXACT [] synonym: "multisynthetase complex" EXACT [] xref: GO:0017101 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0027467 ! MCA1_HUMAN [Term] id: CCO:C0000839 name: methionyl glutamyl tRNA synthetase complex namespace: cellular_component def: "A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers." [GOC:mcc, PMID:11069915] xref: GO:0017102 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000840 name: glutamate-cysteine ligase complex namespace: cellular_component def: "An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine." [EC:6.3.2.2] xref: GO:0017109 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0055404 ! GSH1_HUMAN relationship: location_of CCO:B0055405 ! GSH0_HUMAN [Term] id: CCO:C0000841 name: single-stranded DNA-dependent ATP-dependent DNA helicase complex namespace: cellular_component def: "A protein complex that possesses single-stranded DNA-dependent DNA helicase activity." [GOC:mah] xref: GO:0017117 is_a: CCO:C0001555 ! DNA helicase complex [Term] id: CCO:C0000842 name: Golgi transport complex namespace: cellular_component def: "A complex of proteins that, in vitro, stimulates intra-Golgi transport; a 13S complex, about 800 kDa in size and consists of at least five polypeptides. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p)." [GOC:krc, PMID:9792665] synonym: "COG complex" EXACT [] synonym: "conserved oligomeric Golgi complex" EXACT [] synonym: "Sec34/35 complex" NARROW [] xref: GO:0017119 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0055660 ! COG7_HUMAN relationship: location_of CCO:B0063024 ! COG5_HUMAN relationship: location_of CCO:B0064448 ! COG3_HUMAN-Phosphoserine533 relationship: location_of CCO:B0065888 ! COG4_HUMAN-Phosphotyrosine714 [Term] id: CCO:C0000843 name: UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase complex namespace: cellular_component def: "Heterotrimeric enzyme complex, which in humans is composed of two large subunits of the same size, and one smaller subunit. Functions in the addition of nucleotide-activated sugars onto the polypeptide." [UniProtKB:O15294] xref: GO:0017122 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000844 name: mitochondrial electron transfer flavoprotein complex namespace: cellular_component def: "A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system." [GOC:mtg_sensu, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "electron transfer flavoprotein complex (sensu Eukaryota)" EXACT [] xref: GO:0017133 is_a: CCO:C0001848 ! mitochondrial part is_a: CCO:C0001914 ! electron transfer flavoprotein complex relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000845 name: N-methyl-D-aspartate selective glutamate receptor complex namespace: cellular_component def: "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD." [http://www.bris.ac.uk/Depts/Synaptic/info/glutamate.html] synonym: "NMDA-selective glutamate receptor" EXACT [] xref: GO:0017146 is_a: CCO:C0000545 ! ionotropic glutamate receptor complex relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 [Term] id: CCO:C0000846 name: alpha-glucosidase II complex namespace: cellular_component def: "A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins." [PMID:10464333, PMID:8910335] comment: Note that alpha-glucosidase I functions as a monomer, and therefore does not have a corresponding cellular component term. xref: GO:0017177 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: location_of CCO:B0011943 ! GLU2B_HUMAN-Phosphoserine383 [Term] id: CCO:C0000847 name: translation release factor complex namespace: cellular_component def: "A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome." [ISBN:0198547684] synonym: "eukaryotic peptide chain release factor" EXACT [] synonym: "peptide chain release factor" BROAD [] xref: GO:0018444 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000848 name: polar granule namespace: cellular_component def: "A small protein-containing electron dense organelle, not surrounded by a membrane, that induces the formation of and becomes incorporated into germ cells." [GOC:bf, http://cancerweb.ncl.ac.uk/] synonym: "germline granule" EXACT [] synonym: "nuage" BROAD [] xref: GO:0018994 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: part_of CCO:C0001952 ! pole plasm [Term] id: CCO:C0000849 name: host namespace: cellular_component def: "Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "host organism" EXACT [] xref: GO:0018995 is_a: CCO:C0001753 ! extraorganismal space [Term] id: CCO:C0000850 name: SCF ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063] synonym: "CDL1 complex" EXACT [] synonym: "CRL1 complex" EXACT [] synonym: "Cul1-RING ubiquitin ligase complex" EXACT [] synonym: "cullin-RING ligase 1" EXACT [] synonym: "SCF complex" EXACT [] synonym: "SCF complex substrate recognition subunit" NARROW [] synonym: "Skp1/Cul1/F-box protein complex" EXACT [] xref: GO:0019005 is_a: CCO:C0001248 ! cullin-RING ubiquitin ligase complex relationship: location_of CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:C0000851 name: molybdopterin synthase complex namespace: cellular_component def: "A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits." [GOC:mah, PMID:12571227, PMID:15709772] subset: gosubset_prok synonym: "molybdopterin converting factor complex" EXACT [] xref: GO:0019008 xref: GO:0019009 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000852 name: virion namespace: cellular_component def: "The complete fully infectious extracellular virus particle." [ISBN:0781718325] subset: goslim_pir synonym: "complete virus particle" EXACT [] xref: GO:0019012 is_a: CCO:C0000200 ! cellular_component [Term] id: CCO:C0000853 name: viral nucleocapsid namespace: cellular_component def: "The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle." [ISBN:0781702534] synonym: "core" BROAD [] synonym: "nucleocapsid" EXACT [] xref: GO:0019013 xref: GO:0019014 is_a: CCO:C0001842 ! virion part relationship: part_of CCO:C0000867 ! viral capsid [Term] id: CCO:C0000854 name: viral genome namespace: cellular_component def: "The whole of the genetic information of a virus, contained as either DNA or RNA." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0019015 is_a: CCO:C0001842 ! virion part [Term] id: CCO:C0000855 name: non-segmented viral genome namespace: cellular_component def: "A viral genome that consists of one continuous nucleic acid molecule." [GOC:pk] xref: GO:0019016 is_a: CCO:C0000854 ! viral genome [Term] id: CCO:C0000856 name: segmented viral genome namespace: cellular_component def: "A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion." [ISBN:0121585336] xref: GO:0019017 is_a: CCO:C0000854 ! viral genome [Term] id: CCO:C0000857 name: bipartite viral genome namespace: cellular_component def: "A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion." [ISBN:0121585336] xref: GO:0019018 is_a: CCO:C0000856 ! segmented viral genome [Term] id: CCO:C0000858 name: tripartite viral genome namespace: cellular_component def: "A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion." [ISBN:0121585336] xref: GO:0019019 is_a: CCO:C0000856 ! segmented viral genome [Term] id: CCO:C0000859 name: multipartite viral genome namespace: cellular_component def: "A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion." [ISBN:0121585336] xref: GO:0019020 is_a: CCO:C0000856 ! segmented viral genome [Term] id: CCO:C0000860 name: DNA viral genome namespace: cellular_component def: "A viral genome composed of deoxyribonucleic acid." [ISBN:0121585336] xref: GO:0019021 is_a: CCO:C0000854 ! viral genome [Term] id: CCO:C0000861 name: RNA viral genome namespace: cellular_component def: "A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked." [ISBN:0121585336] xref: GO:0019022 is_a: CCO:C0000854 ! viral genome [Term] id: CCO:C0000862 name: dsRNA viral genome namespace: cellular_component def: "A viral genome composed of double stranded RNA." [ISBN:0121585336] xref: GO:0019023 is_a: CCO:C0000861 ! RNA viral genome [Term] id: CCO:C0000863 name: ssRNA viral genome namespace: cellular_component def: "A viral genome composed of single stranded RNA of either positive or negative sense." [ISBN:0121585336] xref: GO:0019024 is_a: CCO:C0000861 ! RNA viral genome [Term] id: CCO:C0000864 name: positive sense viral genome namespace: cellular_component def: "A single stranded RNA genome with the same nucleotide polarity as mRNA." [ISBN:0121585336] xref: GO:0019025 is_a: CCO:C0000863 ! ssRNA viral genome [Term] id: CCO:C0000865 name: negative sense viral genome namespace: cellular_component def: "A single stranded RNA genome with the opposite nucleotide polarity as mRNA." [ISBN:0121585336] xref: GO:0019026 is_a: CCO:C0000863 ! ssRNA viral genome [Term] id: CCO:C0000866 name: ambisense viral genome namespace: cellular_component def: "A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule." [ISBN:0121585336] xref: GO:0019027 is_a: CCO:C0000863 ! ssRNA viral genome [Term] id: CCO:C0000867 name: viral capsid namespace: cellular_component def: "The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres." [GOC:mtg_sensu, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "viral capsid (sensu Retroviridae)" EXACT [] xref: GO:0019028 xref: GO:0046728 is_a: CCO:C0001842 ! virion part relationship: location_of CCO:B0055625 ! POK4_HUMAN relationship: location_of CCO:B0055629 ! POK12_HUMAN [Term] id: CCO:C0000868 name: helical viral capsid namespace: cellular_component def: "The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure." [ISBN:071673706X] xref: GO:0019029 is_a: CCO:C0000867 ! viral capsid [Term] id: CCO:C0000869 name: icosahedral viral capsid namespace: cellular_component def: "The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Tobacco satellite necrosis virus has such a capsid structure." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:071673706X] synonym: "quasispherical viral capsid" EXACT [] xref: GO:0019030 is_a: CCO:C0000867 ! viral capsid [Term] id: CCO:C0000870 name: viral envelope namespace: cellular_component def: "The lipid bilayer and associated glycoproteins that surround many types of virus particle." [ISBN:0781718325] synonym: "viral glycoprotein" RELATED [] synonym: "viral membrane" EXACT [] xref: GO:0019031 is_a: CCO:C0001842 ! virion part [Term] id: CCO:C0000871 name: viral tegument namespace: cellular_component def: "A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0019033 is_a: CCO:C0001842 ! virion part [Term] id: CCO:C0000872 name: viral replication complex namespace: cellular_component def: "Specific locations and structures in the virus infected cell involved in replicating the viral genome." [ISBN:0781718325] xref: GO:0019034 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000873 name: viral integration complex namespace: cellular_component def: "Virus-specific complex of protein required for integrating viral genomes into the host genome." [ISBN:0781718325] xref: GO:0019035 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 [Term] id: CCO:C0000874 name: viral transcriptional complex namespace: cellular_component def: "Specific locations and structures in the virus infected cell involved in transcribing the viral genome." [ISBN:0781718325] xref: GO:0019036 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000875 name: viral assembly intermediate namespace: cellular_component def: "Specific locations and structures in the virus infected cell involved in assembling new virions." [ISBN:0781718325] xref: GO:0019037 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000876 name: provirus namespace: cellular_component def: "The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle." [ISBN:0121585336] xref: GO:0019038 is_a: CCO:C0000854 ! viral genome is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0000877 name: histamine-gated chloride channel complex namespace: cellular_component def: "A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts." [GOC:mah] xref: GO:0019183 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0000878 name: snRNA-activating protein complex namespace: cellular_component def: "A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters." [PMID:7715707, PMID:9003788] synonym: "SNAPc" EXACT [] xref: GO:0019185 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0070694 ! SNPC4_HUMAN-Phosphothreonine1157 [Term] id: CCO:C0000879 name: phosphoenolpyruvate-dependent sugar phosphotransferase complex namespace: cellular_component def: "Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system)." [GOC:ma] xref: GO:0019197 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000880 name: synaptosome namespace: cellular_component def: "Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. xref: GO:0019717 is_a: CCO:C0000244 ! membrane fraction relationship: location_of CCO:B0002198 ! SEPT3_HUMAN relationship: location_of CCO:B0005602 ! LIPA2_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0026217 ! ITA5_HUMAN relationship: location_of CCO:B0030754 ! VAMP3_HUMAN-Phosphoserine58 relationship: location_of CCO:B0035064 ! KPCG_HUMAN-Phosphoserine687 relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0039664 ! SYUA_HUMAN-Phosphoserine87 relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0055468 ! P2RX1_HUMAN relationship: location_of CCO:B0055954 ! RGRF1_HUMAN relationship: location_of CCO:B0062858 ! SNP23_HUMAN relationship: location_of CCO:B0062896 ! ZMY19_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0067487 ! KS6B1_HUMAN-Phosphoserine441 relationship: location_of CCO:B0067856 ! MAGI2_HUMAN-Phosphotyrosine827 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 [Term] id: CCO:C0000881 name: rough microsome namespace: cellular_component def: "Vesicular particles formed from disrupted endoplasmic reticulum membranes and studded with ribosomes on the outside." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. xref: GO:0019718 is_a: CCO:C0000373 ! microsome [Term] id: CCO:C0000882 name: smooth microsome namespace: cellular_component def: "Vesicular particles formed from disrupted endoplasmic reticulum and plasma membranes without any adhering ribosomes." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. xref: GO:0019719 is_a: CCO:C0000373 ! microsome [Term] id: CCO:C0000885 name: quinolinate synthetase complex namespace: cellular_component def: "A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate." [UniProtKB:P10902] comment: See also the molecular function term 'L-aspartate oxidase activity ; GO:0008734'. subset: gosubset_prok xref: GO:0019804 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000886 name: Type I site-specific deoxyribonuclease complex namespace: cellular_component def: "A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell." [PMID:12654995, PMID:15788748] subset: gosubset_prok synonym: "Type I restriction enzyme complex" EXACT [] xref: GO:0019812 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000887 name: Type III site-specific deoxyribonuclease complex namespace: cellular_component def: "A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell." [PMID:12654995] subset: gosubset_prok synonym: "Type III restriction enzyme complex" EXACT [] xref: GO:0019813 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0000888 name: immunoglobulin complex namespace: cellular_component def: "A multiprotein complex that functions as an antibody. Immunoglobulins (Igs) are composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. The classes of Ig are IgA, IgD, IgE, IgG and IgM; they may be embedded in the plasma membrane or circulate in the blood or lymph." [GOC:jl, ISBN:0140512713] subset: goslim_pir xref: GO:0019814 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0000889 name: B cell receptor complex namespace: cellular_component def: "A membrane-bound antigen receptor complex consisting in its basic form of an antigen-binding subunit (the membrane immunoglobulin or mIg), comprised of two identical heavy chains and two identical light chains held together by disulfide bonds, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [ISBN:0781735149 "Fundamental Immunology"] synonym: "B cell receptor accessory molecule complex" RELATED [] synonym: "B lymphocyte receptor complex" EXACT [] synonym: "B-cell receptor complex" EXACT [] synonym: "B-lymphocyte receptor complex" EXACT [] synonym: "BCR" RELATED [] synonym: "immunoglobulin complex, membrane bound" EXACT [] xref: GO:0019815 xref: GO:0042570 is_a: CCO:C0000888 ! immunoglobulin complex is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0067505 ! KSYK_HUMAN-Phosphotyrosine323 relationship: part_of CCO:C0000186 ! immunological synapse [Term] id: CCO:C0000890 name: P1 peroxisome namespace: cellular_component def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms." [PMID:10629216] comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. synonym: "peroxisome vesicle" BROAD [] xref: GO:0019819 is_a: CCO:C0000359 ! peroxisome [Term] id: CCO:C0000891 name: P2 peroxisome namespace: cellular_component def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed." [PMID:10629216] comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. synonym: "peroxisome vesicle" BROAD [] xref: GO:0019820 is_a: CCO:C0000359 ! peroxisome [Term] id: CCO:C0000892 name: P3 peroxisome namespace: cellular_component def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content." [PMID:10629216] comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. synonym: "peroxisome vesicle" BROAD [] xref: GO:0019821 is_a: CCO:C0000359 ! peroxisome [Term] id: CCO:C0000893 name: P4 peroxisome namespace: cellular_component def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content." [PMID:10629216] comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'. synonym: "peroxisome vesicle" BROAD [] xref: GO:0019822 is_a: CCO:C0000359 ! peroxisome [Term] id: CCO:C0000894 name: P5 peroxisome namespace: cellular_component def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content." [PMID:10629216] comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P6 peroxisome ; GO:0019824'. synonym: "peroxisome vesicle" BROAD [] xref: GO:0019823 is_a: CCO:C0000359 ! peroxisome [Term] id: CCO:C0000895 name: P6 peroxisome namespace: cellular_component def: "A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes." [PMID:10629216] comment: Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P5 peroxisome ; GO:0019823'. synonym: "peroxisome vesicle" BROAD [] xref: GO:0019824 is_a: CCO:C0000359 ! peroxisome [Term] id: CCO:C0000896 name: flagellum namespace: cellular_component def: "Long whiplike or feathery structures borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium." [http://haven.isb-sib.ch/spdocann//dicterms.txt, UniProtKB:kwdictionary] subset: goslim_pir subset: gosubset_prok xref: GO:0008223 xref: GO:0019861 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0012916 ! MET_HUMAN-Phosphotyrosine1356 relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0055873 ! IFT88_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058611 ! ROP1B_HUMAN relationship: location_of CCO:B0062879 ! CTSR1_HUMAN relationship: location_of CCO:B0064039 ! CABYR_HUMAN-Phosphoserine362 relationship: location_of CCO:B0065551 ! AKAP4_HUMAN-Phosphoserine492 [Term] id: CCO:C0000897 name: organelle inner membrane namespace: cellular_component def: "The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites." [GOC:mah] comment: See also the cellular component term 'outer membrane ; GO:0019867'. subset: gosubset_prok xref: GO:0019866 is_a: CCO:C0001127 ! organelle membrane relationship: part_of CCO:C0001360 ! organelle envelope [Term] id: CCO:C0000898 name: outer membrane namespace: cellular_component def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." [http://haven.isb-sib.ch/spdocann//dicterms.txt, UniProtKB:kwdictionary] subset: gosubset_prok xref: GO:0019867 is_a: CCO:C0000766 ! membrane relationship: location_of CCO:B0006116 ! TOM20_HUMAN relationship: location_of CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0014603 ! VDAC2_HUMAN-Phosphoserine115 relationship: location_of CCO:B0014607 ! VDAC3_HUMAN-N6-acetyllysine61 relationship: location_of CCO:B0050997 ! MFN2_HUMAN relationship: location_of CCO:B0055558 ! SYJ2B_HUMAN relationship: location_of CCO:B0057377 ! MIRO2_HUMAN relationship: location_of CCO:B0057378 ! MIRO1_HUMAN relationship: location_of CCO:B0058059 ! CPT1B_HUMAN relationship: location_of CCO:B0058142 ! MUL1_HUMAN relationship: location_of CCO:B0058494 ! AIFM2_HUMAN relationship: location_of CCO:B0059333 ! SHLB1_HUMAN relationship: location_of CCO:B0062893 ! SAM50_HUMAN relationship: location_of CCO:B0064452 ! CPT1A_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0068019 ! MAVS_HUMAN-Phosphothreonine398 relationship: location_of CCO:B0068239 ! MLXIP_HUMAN-Phosphoserine27 [Term] id: CCO:C0000899 name: extrinsic to plasma membrane namespace: cellular_component def: "Loosely bound to one surface of the plasma membrane, but not integrated into the hydrophobic region." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "juxtamembrane" BROAD [] synonym: "peripheral plasma membrane protein" EXACT [] xref: GO:0000157 xref: GO:0019897 is_a: CCO:C0000900 ! extrinsic to membrane is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0006244 ! TDGF1_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:C0000900 name: extrinsic to membrane namespace: cellular_component def: "Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region." [GOC:jl, GOC:mah, http://cancerweb.ncl.ac.uk/] comment: Note that proteins extrinsic to membranes can be removed by treatments that do not disrupt the membrane, such as salt solutions. subset: gosubset_prok synonym: "peripheral membrane protein" EXACT [] xref: GO:0019898 xref: GO:0030396 is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0002064 ! GML_HUMAN relationship: location_of CCO:B0026846 ! CNTFR_HUMAN relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0054321 ! GFRA2_HUMAN relationship: location_of CCO:B0054570 ! GFRA3_HUMAN relationship: location_of CCO:B0054917 ! UROM_HUMAN relationship: location_of CCO:B0055538 ! GFRA1_HUMAN relationship: location_of CCO:B0055723 ! UPAR_HUMAN relationship: location_of CCO:B0063349 ! PTN4_HUMAN relationship: location_of CCO:B0065965 ! E41L3_HUMAN-Phosphothreonine703 relationship: location_of CCO:B0066128 ! FARP1_HUMAN-Phosphoserine896 relationship: location_of CCO:B0066133 ! FARP2_HUMAN-Phosphoserine881 [Term] id: CCO:C0000901 name: cyclin-dependent protein kinase activating kinase holoenzyme complex namespace: cellular_component def: "A protein complex that phosphorylates cyclin-dependent kinases such as Cdc2 on Thr161 (or an equivalent residue); contains a catalytic subunit and a regulatory subunit, and some examples also include an assembly factor." [GOC:mah, PMID:8752210] synonym: "CAK complex" EXACT [] synonym: "CDK-activating kinase complex" EXACT [] xref: GO:0019907 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0005451 ! HXC10_HUMAN relationship: location_of CCO:B0011000 ! CCNH_HUMAN-Phosphothreonine315 relationship: location_of CCO:B0011197 ! CH60_HUMAN-Phosphoserine70 relationship: location_of CCO:B0026248 ! ERCC2_HUMAN relationship: location_of CCO:B0067179 ! JAD1A_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0069621 ! PUF60_HUMAN-Phosphothreonine60 [Term] id: CCO:C0000902 name: nuclear cyclin-dependent protein kinase holoenzyme complex namespace: cellular_component def: "Cyclin-dependent protein kinase (CDK) complex found in the nucleus." [GOC:krc] synonym: "CDK holoenzyme" BROAD [] xref: GO:0019908 is_a: CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0000903 name: mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex namespace: cellular_component def: "A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex." [GOC:mtg_sensu, UniProtKB:P35816] comment: See also the cellular component term 'mitochondrial pyruvate dehydrogenase complex ; GO:0005967'. synonym: "pyruvate dehydrogenase (lipoamide) phosphatase complex (sensu Eukaryota)" EXACT [] xref: GO:0019910 is_a: CCO:C0001848 ! mitochondrial part is_a: CCO:C0001916 ! pyruvate dehydrogenase (lipoamide) phosphatase complex relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000904 name: host cell plasma membrane namespace: cellular_component def: "The plasma membrane surrounding a host cell." [GOC:mb] subset: gosubset_prok xref: GO:0020002 is_a: CCO:C0001589 ! host cell membrane [Term] id: CCO:C0000905 name: parasitophorous vacuole namespace: cellular_component def: "Vacuole within a host cell in which a parasite resides." [GOC:mb] xref: GO:0020003 is_a: CCO:C0000355 ! vacuole is_a: CCO:C0001599 ! host cell cytoplasm part is_a: CCO:C0001746 ! extracellular organelle [Term] id: CCO:C0000906 name: parasitophorous vacuolar space namespace: cellular_component def: "Space between a parasite plasma membrane and the parasitophorous vacuolar membrane." [GOC:mb] xref: GO:0020004 is_a: CCO:C0000357 ! vacuolar lumen is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000905 ! parasitophorous vacuole [Term] id: CCO:C0000907 name: parasitophorous vacuolar membrane namespace: cellular_component def: "The lipid bilayer surrounding a parasitophorous vacuole." [GOC:mb] xref: GO:0020005 is_a: CCO:C0000356 ! vacuolar membrane is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000905 ! parasitophorous vacuole [Term] id: CCO:C0000908 name: parasitophorous vacuolar membrane network namespace: cellular_component def: "Tubular network of extensions from the parasitophorous vacuolar membrane that protrude into the host cytoplasm." [PMID:3528173] synonym: "tubulovesicular network" NARROW [] xref: GO:0020006 is_a: CCO:C0000356 ! vacuolar membrane is_a: CCO:C0001840 ! extracellular region part is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0000907 ! parasitophorous vacuolar membrane [Term] id: CCO:C0000909 name: apical complex namespace: cellular_component def: "Protruding complex at the anterior end of some life cycle stages of all apicomplexan parasites, involved in both the attachment and penetration of the host cell by the parasite." [GOC:mb] xref: GO:0020007 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0001896 ! apical part of cell [Term] id: CCO:C0000910 name: rhoptry namespace: cellular_component def: "A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole." [ISBN:0521664470, PMID:11801218, PMID:16002398] synonym: "paired organelles" RELATED [] synonym: "toxoneme" RELATED [] xref: GO:0020008 is_a: CCO:C0001882 ! cell part is_a: CCO:C0002133 ! extracellular membrane-bounded organelle relationship: part_of CCO:C0000909 ! apical complex [Term] id: CCO:C0000911 name: microneme namespace: cellular_component def: "A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the three specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell." [ISBN:0521664470, PMID:11801218] synonym: "sarconeme" RELATED [] xref: GO:0020009 is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: part_of CCO:C0000909 ! apical complex [Term] id: CCO:C0000912 name: conoid namespace: cellular_component def: "A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of mictotubules." [GOC:expert_dr, PMID:11901169, PMID:16518471] xref: GO:0020010 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0000909 ! apical complex [Term] id: CCO:C0000913 name: apicoplast namespace: cellular_component def: "The plastid organelle found in apicomplexans." [ISBN:0521664470] xref: GO:0020011 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0000914 name: glycosome namespace: cellular_component def: "A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis." [GOC:mb] subset: goslim_pir xref: GO:0020015 is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0000915 name: flagellar pocket namespace: cellular_component def: "Invagination of the plasma membrane from which a flagellum protrudes." [GOC:mb] xref: GO:0020016 is_a: CCO:C0001861 ! microtubule-based flagellum part [Term] id: CCO:C0000916 name: flagellar membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the flagellum." [GOC:mah, GOC:mb] xref: GO:0020017 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001173 ! cell projection membrane is_a: CCO:C0001861 ! microtubule-based flagellum part [Term] id: CCO:C0000917 name: flagellar pocket membrane namespace: cellular_component def: "That part of the plasma membrane found in the flagellar pocket." [GOC:mb] xref: GO:0020018 is_a: CCO:C0000916 ! flagellar membrane relationship: part_of CCO:C0000915 ! flagellar pocket [Term] id: CCO:C0000918 name: food vacuole namespace: cellular_component def: "Vacuole within a parasite used for digestion of the host cell cytoplasm." [GOC:mb] synonym: "digestive vacuole" EXACT [] synonym: "food vacuole (sensu Apicomplexa)" EXACT [] xref: GO:0005772 xref: GO:0020020 is_a: CCO:C0001382 ! phagolysosome [Term] id: CCO:C0000919 name: acidocalcisome namespace: cellular_component def: "An electron-dense acidic organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations." [GOC:mb] subset: goslim_pir synonym: "metachromatic granule" EXACT [PMID:15738951] synonym: "polyphosphate vacuole" RELATED [PMID:15738951] synonym: "volutin granule" EXACT [PMID:15738951] xref: GO:0020022 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0000920 name: kinetoplast namespace: cellular_component def: "A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum." [GOC:mb] xref: GO:0020023 is_a: CCO:C0001848 ! mitochondrial part [Term] id: CCO:C0000921 name: subpellicular microtubule namespace: cellular_component def: "Singlet microtubules that lie underneath the inner membrane complex and emanate from the basal ring of the conoid." [GOC:mb] xref: GO:0020025 is_a: CCO:C0000434 ! microtubule relationship: part_of CCO:C0000909 ! apical complex [Term] id: CCO:C0000922 name: merozoite dense granule namespace: cellular_component def: "Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell." [GOC:mb, GOC:mtg_sensu] synonym: "dense body" EXACT [] synonym: "dense granule (sensu Apicomplexa)" EXACT [] xref: GO:0020026 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0000923 name: infected host cell surface knob namespace: cellular_component def: "Protrusion that develops in the plasma membrane of a parasitized erythrocyte." [GOC:mb] synonym: "knob (sensu Plasmodium)" EXACT [] xref: GO:0020030 is_a: CCO:C0001599 ! host cell cytoplasm part [Term] id: CCO:C0000924 name: polar ring of apical complex namespace: cellular_component def: "An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite." [GOC:mb, PMID:16518471] synonym: "anterior polar ring of apical complex" EXACT [] synonym: "upper polar ring of apical complex" EXACT [] xref: GO:0020031 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0000909 ! apical complex [Term] id: CCO:C0000925 name: basal ring of apical complex namespace: cellular_component def: "An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite." [GOC:mah, PMID:16518471] synonym: "lower polar ring of apical complex" EXACT [] synonym: "posterior polar ring of apical complex" EXACT [] synonym: "preconoidal ring of apical complex" EXACT [] xref: GO:0020032 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0000909 ! apical complex [Term] id: CCO:C0000926 name: Maurer's cleft namespace: cellular_component def: "A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton." [PMID:16705161] xref: GO:0020036 is_a: CCO:C0001599 ! host cell cytoplasm part [Term] id: CCO:C0000927 name: subpellicular network namespace: cellular_component def: "A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton." [PMID:11420112] xref: GO:0020038 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0000928 ! pellicle [Term] id: CCO:C0000928 name: pellicle namespace: cellular_component def: "The cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles." [GOC:mb] xref: GO:0020039 is_a: CCO:C0001849 ! cytoskeletal part [Term] id: CCO:C0000929 name: TRAPP complex namespace: cellular_component def: "A large complex present on the cis-Golgi that acts prior to SNARE complex assembly to mediate vesicle docking and fusion." [PMID:9564032] synonym: "transport protein particle" EXACT [] xref: GO:0030008 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001850 ! Golgi apparatus part relationship: part_of CCO:C0000380 ! cis-Golgi network [Term] id: CCO:C0000930 name: CCR4-NOT complex namespace: cellular_component def: "A large multimeric transcription factor complex that can regulate transcription positively or negatively; consists of a core complex plus additional proteins; may interact with other proteins to control initiation of transcription. In Saccharomyces the core complex comprises Ccr4p, Caf1p, Not1p, Not2p, Not3p, Not4p, and Not5p; Caf4p, Caf16p, and several less well characterized proteins." [PMID:11113136] xref: GO:0030014 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0050528 ! CNOT7_HUMAN [Term] id: CCO:C0000931 name: CCR4-NOT core complex namespace: cellular_component def: "The core of the CCR4-NOT transcription factor complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Not1p, Not2p, Not3p, Not4p, and Not5p." [PMID:11113136] xref: GO:0030015 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: part_of CCO:C0000930 ! CCR4-NOT complex [Term] id: CCO:C0000932 name: myofibril namespace: cellular_component def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194] synonym: "striated muscle fiber" EXACT [] synonym: "striated muscle fibre" EXACT [] xref: GO:0030016 is_a: CCO:C0001766 ! contractile fiber relationship: location_of CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: location_of CCO:B0054982 ! MLRV_HUMAN [Term] id: CCO:C0000933 name: sarcomere namespace: cellular_component def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194] xref: GO:0030017 is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0005250 ! MYOZ2_HUMAN relationship: location_of CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: location_of CCO:B0015288 ! ARF1_HUMAN relationship: location_of CCO:B0015638 ! ACTC_HUMAN relationship: location_of CCO:B0024617 ! MMP2_HUMAN relationship: location_of CCO:B0036526 ! MYLK2_HUMAN relationship: location_of CCO:B0054982 ! MLRV_HUMAN relationship: location_of CCO:B0056023 ! MYPC3_HUMAN relationship: location_of CCO:B0057419 ! ABRA_HUMAN relationship: location_of CCO:B0071477 ! TPM1_HUMAN-N-acetylmethionine1 relationship: part_of CCO:C0000932 ! myofibril [Term] id: CCO:C0000934 name: Z disc namespace: cellular_component def: "Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached." [GOC:mtg_muscle, ISBN:0815316194] synonym: "Z band" EXACT [] synonym: "Z disk" EXACT [] synonym: "Z line" EXACT [] xref: GO:0030018 is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0005250 ! MYOZ2_HUMAN relationship: location_of CCO:B0005387 ! TELT_HUMAN relationship: location_of CCO:B0005948 ! ACTN1_HUMAN relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0012493 ! K2C8_HUMAN-Phosphoserine27 relationship: location_of CCO:B0014383 ! TITIN_HUMAN-Phosphoserine9203 relationship: location_of CCO:B0042127 ! BMP10_HUMAN relationship: location_of CCO:B0055127 ! NEBU_HUMAN relationship: location_of CCO:B0059198 ! ITBP2_HUMAN relationship: location_of CCO:B0063156 ! SRBS2_HUMAN relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: part_of CCO:C0001328 ! I band [Term] id: CCO:C0000935 name: lamellipodium namespace: cellular_component def: "A thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments." [ISBN:0815316194] xref: GO:0030027 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0001344 ! APBB1_HUMAN relationship: location_of CCO:B0001546 ! NDKB_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0001998 ! Q8TEY4_HUMAN relationship: location_of CCO:B0002020 ! APBB2_HUMAN relationship: location_of CCO:B0005512 ! AKT1_HUMAN relationship: location_of CCO:B0005942 ! WASL_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0025035 ! Q7Z324_HUMAN relationship: location_of CCO:B0034567 ! ARP3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0038093 ! ABI3_HUMAN relationship: location_of CCO:B0038095 ! ABI2_HUMAN relationship: location_of CCO:B0054370 ! ITBP1_HUMAN relationship: location_of CCO:B0054441 ! ARPC5_HUMAN relationship: location_of CCO:B0054499 ! SPY1_HUMAN relationship: location_of CCO:B0057029 ! FGD5_HUMAN relationship: location_of CCO:B0057198 ! FGD2_HUMAN relationship: location_of CCO:B0057306 ! PDPN_HUMAN relationship: location_of CCO:B0058282 ! FGD4_HUMAN relationship: location_of CCO:B0059177 ! DBNL_HUMAN relationship: location_of CCO:B0062775 ! TESC_HUMAN relationship: location_of CCO:B0063370 ! SRC8_HUMAN relationship: location_of CCO:B0065175 ! EVL_HUMAN-Phosphoserine306 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0065618 ! AMOT_HUMAN-Phosphoserine312 relationship: location_of CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: location_of CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: location_of CCO:B0066179 ! FGD3_HUMAN-Phosphoserine128 relationship: location_of CCO:B0066183 ! FGD6_HUMAN-Phosphoserine721 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0071823 ! WASF2_HUMAN-Phosphoserine482 relationship: part_of CCO:C0001172 ! leading edge [Term] id: CCO:C0000936 name: cell junction namespace: cellular_component def: "A specialized region of connection between two cells or between a cell and the extracellular matrix." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030054 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0002059 ! LAP2_HUMAN relationship: location_of CCO:B0002060 ! NEB2_HUMAN relationship: location_of CCO:B0002112 ! PAR6G_HUMAN relationship: location_of CCO:B0002113 ! PAR6B_HUMAN relationship: location_of CCO:B0002150 ! PAR6A_HUMAN relationship: location_of CCO:B0002198 ! SEPT3_HUMAN relationship: location_of CCO:B0002248 ! LZTS1_HUMAN relationship: location_of CCO:B0005837 ! PAXI_HUMAN relationship: location_of CCO:B0005934 ! WNK4_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0005954 ! DTNA_HUMAN relationship: location_of CCO:B0006029 ! PANX3_HUMAN relationship: location_of CCO:B0006285 ! GRIK5_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010760 ! BCAR1_HUMAN-Phosphotyrosine362 relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: location_of CCO:B0011370 ! CTNA1_HUMAN-Phosphoserine655 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0011527 ! DLG5_HUMAN-Phosphothreonine1011 relationship: location_of CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: location_of CCO:B0011824 ! FAK1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0011920 ! GAK_HUMAN-Phosphoserine829 relationship: location_of CCO:B0013375 ! PAK1_HUMAN-Phosphoserine21 relationship: location_of CCO:B0013388 ! PAR3L_HUMAN-Phosphoserine730 relationship: location_of CCO:B0013393 ! PARD3_HUMAN-Phosphoserine717 relationship: location_of CCO:B0013517 ! PININ_HUMAN-Phosphoserine96 relationship: location_of CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0019132 ! RHG17_HUMAN relationship: location_of CCO:B0020605 ! GRIK3_HUMAN relationship: location_of CCO:B0020611 ! GRIK2_HUMAN relationship: location_of CCO:B0020614 ! GRIK1_HUMAN relationship: location_of CCO:B0020617 ! GRIK4_HUMAN relationship: location_of CCO:B0020623 ! GRIA4_HUMAN relationship: location_of CCO:B0022899 ! GBRR2_HUMAN relationship: location_of CCO:B0022900 ! GBRG3_HUMAN relationship: location_of CCO:B0022901 ! GBRE_HUMAN relationship: location_of CCO:B0022902 ! Q8IYR7_HUMAN relationship: location_of CCO:B0022903 ! GBRT_HUMAN relationship: location_of CCO:B0022906 ! GBRG1_HUMAN relationship: location_of CCO:B0022907 ! GBRA6_HUMAN relationship: location_of CCO:B0022909 ! GBRG2_HUMAN relationship: location_of CCO:B0022911 ! GLRB_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022914 ! GBRA1_HUMAN relationship: location_of CCO:B0022915 ! GBRA5_HUMAN relationship: location_of CCO:B0022917 ! GLRA2_HUMAN relationship: location_of CCO:B0022924 ! GBRA2_HUMAN relationship: location_of CCO:B0022926 ! GBRR1_HUMAN relationship: location_of CCO:B0022931 ! GBRD_HUMAN relationship: location_of CCO:B0022933 ! GBRA3_HUMAN relationship: location_of CCO:B0022935 ! Q6PCC3_HUMAN relationship: location_of CCO:B0022999 ! PTPRK_HUMAN relationship: location_of CCO:B0023320 ! DLG2_HUMAN relationship: location_of CCO:B0026380 ! JUB_HUMAN-Phosphoserine119 relationship: location_of CCO:B0027056 ! A8MWU7_HUMAN relationship: location_of CCO:B0028914 ! AB1IP_HUMAN relationship: location_of CCO:B0030754 ! VAMP3_HUMAN-Phosphoserine58 relationship: location_of CCO:B0031065 ! FBLI1_HUMAN relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0032799 ! ACHB3_HUMAN relationship: location_of CCO:B0032804 ! ACHA3_HUMAN relationship: location_of CCO:B0032806 ! ACHA5_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0032809 ! ACHA2_HUMAN relationship: location_of CCO:B0034706 ! DLG4_HUMAN-Phosphotyrosine432 relationship: location_of CCO:B0034992 ! KCC2A_HUMAN-Phosphothreonine286 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035292 ! NMDE4_HUMAN-Phosphoserine1326 relationship: location_of CCO:B0035773 ! TGFI1_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0041576 ! WTIP_HUMAN relationship: location_of CCO:B0042293 ! ACHG_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0042506 ! DESP_HUMAN relationship: location_of CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 relationship: location_of CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: location_of CCO:B0043382 ! STAR8_HUMAN-Phosphoserine238 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0049698 ! CLD7_HUMAN relationship: location_of CCO:B0054420 ! NPHP1_HUMAN relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0054764 ! CXB6_HUMAN relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0055907 ! ILK_HUMAN relationship: location_of CCO:B0055947 ! PKP1_HUMAN relationship: location_of CCO:B0056077 ! DIXC1_HUMAN relationship: location_of CCO:B0056938 ! SHC4_HUMAN relationship: location_of CCO:B0056974 ! DNMBP_HUMAN relationship: location_of CCO:B0057113 ! RHOU_HUMAN relationship: location_of CCO:B0057307 ! HOME1_HUMAN relationship: location_of CCO:B0057438 ! RHG24_HUMAN relationship: location_of CCO:B0057446 ! NLGN1_HUMAN relationship: location_of CCO:B0057556 ! UN13C_HUMAN relationship: location_of CCO:B0057992 ! CPLX3_HUMAN relationship: location_of CCO:B0058358 ! MAGI1_HUMAN relationship: location_of CCO:B0058423 ! P2RX4_HUMAN relationship: location_of CCO:B0058577 ! PCD24_HUMAN relationship: location_of CCO:B0058646 ! ACH10_HUMAN relationship: location_of CCO:B0058854 ! NOX4_HUMAN relationship: location_of CCO:B0058913 ! HOME2_HUMAN relationship: location_of CCO:B0059343 ! GRIP1_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062858 ! SNP23_HUMAN relationship: location_of CCO:B0062873 ! LIMS1_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0063442 ! TUTLA_HUMAN relationship: location_of CCO:B0063628 ! ASH1L_HUMAN-Phosphoserine22 relationship: location_of CCO:B0064229 ! CDGAP_HUMAN-Phosphoserine1106 relationship: location_of CCO:B0064449 ! CPEB1_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0064451 ! CPLX4_HUMAN-Cysteine methyl ester157 relationship: location_of CCO:B0064569 ! CTBP2_HUMAN-Phosphoserine428 relationship: location_of CCO:B0064579 ! CTND2_HUMAN-Phosphoserine415 relationship: location_of CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: location_of CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: location_of CCO:B0065466 ! AFAD_HUMAN-Phosphoserine215 relationship: location_of CCO:B0065618 ! AMOT_HUMAN-Phosphoserine312 relationship: location_of CCO:B0065880 ! CLD12_HUMAN-Phosphoserine228 relationship: location_of CCO:B0065918 ! CXAR_HUMAN-Phosphoserine300 relationship: location_of CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: location_of CCO:B0066163 ! FERM2_HUMAN-Phosphoserine181 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066606 ! GRIA2_HUMAN-Phosphoserine880 relationship: location_of CCO:B0066608 ! GRIA3_HUMAN-Phosphotyrosine887 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0066889 ! HOME3_HUMAN-Phosphoserine159 relationship: location_of CCO:B0067093 ! INADL_HUMAN-Phosphoserine455 relationship: location_of CCO:B0067487 ! KS6B1_HUMAN-Phosphoserine441 relationship: location_of CCO:B0067657 ! LIMA1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0067856 ! MAGI2_HUMAN-Phosphotyrosine827 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068580 ! NEUM_HUMAN-Phosphoserine41 relationship: location_of CCO:B0068587 ! NEXN_HUMAN-Phosphoserine365 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0068994 ! OREX_HUMAN-Methionine amide97 relationship: location_of CCO:B0069015 ! P2RX6_HUMAN-Phosphotyrosine54 relationship: location_of CCO:B0069116 ! PARVA_HUMAN-Phosphoserine19 relationship: location_of CCO:B0069212 ! PEPL_HUMAN-Phosphothreonine1579 relationship: location_of CCO:B0069380 ! PKP2_HUMAN-Phosphoserine329 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: location_of CCO:B0069566 ! PSD3_HUMAN-Phosphoserine1011 relationship: location_of CCO:B0069665 ! RAB13_HUMAN-Phosphoserine178 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070479 ! SHAN2_HUMAN-Phosphoserine1113 relationship: location_of CCO:B0070486 ! SHAN3_HUMAN-Phosphoserine783 relationship: location_of CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 relationship: location_of CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 relationship: location_of CCO:B0070697 ! SNTA1_HUMAN-Phosphoserine189 relationship: location_of CCO:B0070704 ! SNTB1_HUMAN-Phosphoserine389 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0071048 ! SYN1_HUMAN-Phosphotyrosine312 relationship: location_of CCO:B0071331 ! TENC1_HUMAN-Phosphoserine835 relationship: location_of CCO:B0071732 ! UN13A_HUMAN-Phosphoserine245 relationship: location_of CCO:B0071733 ! UN13B_HUMAN-Phosphothreonine605 relationship: location_of CCO:B0071778 ! VASP_HUMAN-Phosphotyrosine39 relationship: location_of CCO:B0071803 ! VINEX_HUMAN-Phosphothreonine529 relationship: location_of CCO:B0072275 ! ZO3_HUMAN-Phosphoserine579 [Term] id: CCO:C0000938 name: hemidesmosome namespace: cellular_component def: "Point of contact between the basal surface of epithelial cells and the basal lamina. Morphologically resembles desmosomes; attached to intermediate filaments." [ISBN:0815316208] xref: GO:0030056 is_a: CCO:C0002136 ! cell-substrate junction relationship: location_of CCO:B0002059 ! LAP2_HUMAN relationship: location_of CCO:B0034592 ! BPA1_HUMAN-Phosphothreonine224 relationship: part_of CCO:C0000706 ! basal plasma membrane [Term] id: CCO:C0000939 name: desmosome namespace: cellular_component def: "A specialised type of cell junction into which intermediate filaments of adjacent cells are inserted. This type of cell junction is characteristic of epithelia. Desmosomes are particularly conspicuous in tissues such as skin that have to withstand mechanical stress." [GOC:mtg_muscle, ISBN:0815316208] synonym: "macula adherens" EXACT [] synonym: "spot desmosome" EXACT [] xref: GO:0030057 is_a: CCO:C0000463 ! intercellular junction relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055947 ! PKP1_HUMAN relationship: location_of CCO:B0069380 ! PKP2_HUMAN-Phosphoserine329 relationship: location_of CCO:B0069382 ! PLAK_HUMAN-Phosphotyrosine660 relationship: part_of CCO:C0000743 ! intercalated disc relationship: part_of CCO:C0001769 ! apical junction complex [Term] id: CCO:C0000940 name: mitochondrial crista namespace: cellular_component def: "Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'. synonym: "mitochondrial cristae" EXACT [] xref: GO:0030061 is_a: CCO:C0001874 ! mitochondrial membrane part relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0000941 name: mitochondrial tricarboxylic acid cycle enzyme complex namespace: cellular_component def: "Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu] synonym: "TCA cycle enzyme complex (sensu Eukaryota)" EXACT [] synonym: "tricarboxylic acid cycle enzyme complex (sensu Eukaryota)" EXACT [] xref: GO:0030062 is_a: CCO:C0001848 ! mitochondrial part is_a: CCO:C0001903 ! tricarboxylic acid cycle enzyme complex relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0000942 name: plasma membrane-derived thylakoid namespace: cellular_component def: "A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "thylakoid (sensu Cyanobacteria)" EXACT [] xref: GO:0030075 is_a: CCO:C0000689 ! thylakoid is_a: CCO:C0001688 ! chromatophore [Term] id: CCO:C0000943 name: light-harvesting complex namespace: cellular_component def: "A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center." [GOC:lr] subset: goslim_pir subset: gosubset_prok synonym: "antenna complex" RELATED [] xref: GO:0030076 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000944 name: plasma membrane light-harvesting complex namespace: cellular_component def: "A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "light-harvesting complex (sensu Gram-negative Bacteria)" EXACT [] synonym: "light-harvesting complex (sensu Proteobacteria)" EXACT [] xref: GO:0030077 is_a: CCO:C0000943 ! light-harvesting complex is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0001688 ! chromatophore [Term] id: CCO:C0000945 name: light-harvesting complex, core complex namespace: cellular_component def: "Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria." [GOC:lr] subset: gosubset_prok xref: GO:0030078 is_a: CCO:C0000944 ! plasma membrane light-harvesting complex [Term] id: CCO:C0000946 name: light-harvesting complex, peripheral complex namespace: cellular_component def: "Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center." [GOC:lr] subset: gosubset_prok xref: GO:0030079 is_a: CCO:C0000944 ! plasma membrane light-harvesting complex [Term] id: CCO:C0000947 name: B875 antenna complex namespace: cellular_component def: "Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm." [GOC:kd] subset: gosubset_prok synonym: "LH1 complex" EXACT [] synonym: "light harvesting complex I" EXACT [] xref: GO:0030080 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0000945 ! light-harvesting complex, core complex [Term] id: CCO:C0000948 name: B800-820 antenna complex namespace: cellular_component def: "Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex." [GOC:kd, GOC:lr] subset: gosubset_prok synonym: "LH3 complex" EXACT [] synonym: "light harvesting complex III" EXACT [] xref: GO:0030081 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0000946 ! light-harvesting complex, peripheral complex [Term] id: CCO:C0000949 name: B800-850 antenna complex namespace: cellular_component def: "Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex." [GOC:kd, GOC:lr] subset: gosubset_prok synonym: "LH2 complex" EXACT [] synonym: "light harvesting complex II" EXACT [] xref: GO:0030082 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0000946 ! light-harvesting complex, peripheral complex [Term] id: CCO:C0000950 name: PSI associated light-harvesting complex I, LHCIa subcomplex namespace: cellular_component def: "A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm." [PMID:8825475] xref: GO:0030083 is_a: CCO:C0000647 ! PSI associated light-harvesting complex I [Term] id: CCO:C0000951 name: PSI associated light-harvesting complex I, LHCIb subcomplex namespace: cellular_component def: "A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm." [PMID:8825475] xref: GO:0030084 is_a: CCO:C0000647 ! PSI associated light-harvesting complex I [Term] id: CCO:C0000952 name: PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex namespace: cellular_component def: "A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides." [PMID:8825475] xref: GO:0030085 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000692 ! PSII associated light-harvesting complex II, peripheral complex [Term] id: CCO:C0000953 name: phycobilisome namespace: cellular_component def: "Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0030089 is_a: CCO:C0000943 ! light-harvesting complex is_a: CCO:C0001852 ! cytoplasmic vesicle part is_a: CCO:C0001854 ! plastid part is_a: CCO:C0001855 ! thylakoid part is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000701 ! cyanelle thylakoid relationship: part_of CCO:C0000942 ! plasma membrane-derived thylakoid [Term] id: CCO:C0000955 name: chloroplast photosystem I namespace: cellular_component def: "Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin." [GOC:jic, GOC:mtg_sensu] synonym: "photosystem I (sensu Magnoliophyta)" EXACT [] xref: GO:0030093 is_a: CCO:C0000650 ! photosystem I is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000663 ! chloroplast thylakoid membrane [Term] id: CCO:C0000956 name: plasma membrane-derived photosystem I namespace: cellular_component def: "A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin." [GOC:jic, GOC:mtg_sensu] subset: gosubset_prok synonym: "photosystem I (sensu Cyanobacteria)" EXACT [] synonym: "plasma membrane photosystem I" EXACT [] xref: GO:0030094 is_a: CCO:C0000650 ! photosystem I is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000942 ! plasma membrane-derived thylakoid [Term] id: CCO:C0000957 name: chloroplast photosystem II namespace: cellular_component def: "An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone." [GOC:jic, GOC:mtg_sensu] synonym: "photosystem II (sensu Viridiplantae)" EXACT [] xref: GO:0030095 is_a: CCO:C0000651 ! photosystem II is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0000663 ! chloroplast thylakoid membrane [Term] id: CCO:C0000958 name: plasma membrane-derived thylakoid photosystem II namespace: cellular_component def: "A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone." [GOC:jic, GOC:mtg_sensu] subset: gosubset_prok synonym: "photosystem II (sensu Cyanobacteria)" EXACT [] synonym: "plasma membrane photosystem II" EXACT [] xref: GO:0030096 is_a: CCO:C0000651 ! photosystem II is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000942 ! plasma membrane-derived thylakoid [Term] id: CCO:C0000959 name: glycocalyx namespace: cellular_component def: "A viscous, carbohydrate rich layer at the outermost periphery of a cell." [GOC:mlg, ISBN:0815316208] subset: goslim_pir subset: gosubset_prok xref: GO:0030112 is_a: CCO:C0000999 ! external encapsulating structure relationship: location_of CCO:B0055034 ! B4GT1_HUMAN [Term] id: CCO:C0000960 name: slime layer namespace: cellular_component def: "A Slime layer is an easily removed, diffuse, unorganised layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids." [GOC:mlg, http://www.wikipedia.org/] xref: GO:0030114 is_a: CCO:C0000959 ! glycocalyx [Term] id: CCO:C0000961 name: S-layer namespace: cellular_component def: "A crystalline protein layer surrounding some bacteria." [GOC:mlg, ISBN:0815108893] subset: goslim_pir subset: gosubset_prok xref: GO:0030115 is_a: CCO:C0000999 ! external encapsulating structure [Term] id: CCO:C0000962 name: membrane coat namespace: cellular_component def: "Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules." [GOC:mah] xref: GO:0030117 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0005197 ! AP2B1_HUMAN relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0038202 ! COPA_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0055510 ! AP2S1_HUMAN relationship: location_of CCO:B0058066 ! AP3S1_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: location_of CCO:B0063204 ! AP1B1_HUMAN relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: location_of CCO:B0065667 ! AP3B1_HUMAN-Phosphoserine609 relationship: location_of CCO:B0065672 ! AP3D1_HUMAN-Phosphoserine759 relationship: part_of CCO:C0001997 ! coated membrane [Term] id: CCO:C0000963 name: clathrin coat namespace: cellular_component def: "A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes." [GOC:mah, PMID:11252894, PMID:9531549] synonym: "clathrin cage" EXACT [] xref: GO:0016190 xref: GO:0030118 is_a: CCO:C0000962 ! membrane coat relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063531 ! CLCB_HUMAN [Term] id: CCO:C0000964 name: AP-type membrane coat adaptor complex namespace: cellular_component def: "Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa)." [GOC:mah, PMID:10611976, PMID:15473838] subset: goslim_pir synonym: "clathrin adaptor" RELATED [] xref: GO:0030119 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0058066 ! AP3S1_HUMAN relationship: part_of CCO:C0000962 ! membrane coat [Term] id: CCO:C0000965 name: vesicle coat namespace: cellular_component def: "A membrane coat found on a coated vesicle." [GOC:mah] xref: GO:0030120 is_a: CCO:C0000962 ! membrane coat is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0001027 ! coated vesicle membrane [Term] id: CCO:C0000966 name: AP-1 adaptor complex namespace: cellular_component def: "An AP-type membrane coat adaptor complex that consists of beta1, gamma1, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network." [GOC:mah, PMID:10611976] synonym: "HA1" EXACT [] synonym: "HA1 clathrin adaptor" EXACT [] xref: GO:0030121 is_a: CCO:C0000976 ! clathrin adaptor complex is_a: CCO:C0001850 ! Golgi apparatus part is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: location_of CCO:B0056547 ! ARH_HUMAN relationship: part_of CCO:C0000975 ! clathrin coat of trans-Golgi network vesicle [Term] id: CCO:C0000967 name: AP-2 adaptor complex namespace: cellular_component def: "An AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles." [GOC:mah, PMID:10611976] synonym: "HA2" EXACT [] synonym: "HA2 clathrin adaptor" EXACT [] xref: GO:0030122 is_a: CCO:C0000976 ! clathrin adaptor complex is_a: CCO:C0001852 ! cytoplasmic vesicle part is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0011656 ! EGFR_HUMAN-Phosphoserine995 relationship: location_of CCO:B0055510 ! AP2S1_HUMAN relationship: location_of CCO:B0056547 ! ARH_HUMAN relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: part_of CCO:C0000973 ! clathrin coat of endocytic vesicle relationship: part_of CCO:C0000977 ! clathrin coat of coated pit [Term] id: CCO:C0000968 name: AP-3 adaptor complex namespace: cellular_component def: "An AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes; it is not clear whether AP-3 forms clathrin coats in vivo." [GOC:mah, PMID:10611976] xref: GO:0030123 is_a: CCO:C0000964 ! AP-type membrane coat adaptor complex [Term] id: CCO:C0000969 name: AP-4 adaptor complex namespace: cellular_component def: "An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo." [GOC:mah, PMID:10611976] xref: GO:0030124 is_a: CCO:C0000964 ! AP-type membrane coat adaptor complex [Term] id: CCO:C0000970 name: clathrin vesicle coat namespace: cellular_component def: "A clathrin coat found on a vesicle." [GOC:mah] xref: GO:0030125 is_a: CCO:C0000963 ! clathrin coat is_a: CCO:C0000965 ! vesicle coat relationship: location_of CCO:B0062791 ! NECP2_HUMAN relationship: part_of CCO:C0001029 ! clathrin coated vesicle membrane [Term] id: CCO:C0000971 name: COPI vesicle coat namespace: cellular_component def: "One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state." [GOC:mah, PMID:11252894] synonym: "coatomer" EXACT [] xref: GO:0017167 xref: GO:0030126 is_a: CCO:C0000965 ! vesicle coat is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0038202 ! COPA_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: part_of CCO:C0001028 ! COPI coated vesicle membrane [Term] id: CCO:C0000972 name: COPII vesicle coat namespace: cellular_component def: "One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state." [GOC:mah, PMID:11252894] xref: GO:0030127 is_a: CCO:C0000965 ! vesicle coat is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: part_of CCO:C0000735 ! ER to Golgi transport vesicle membrane [Term] id: CCO:C0000973 name: clathrin coat of endocytic vesicle namespace: cellular_component def: "A clathrin coat found on an endocytic vesicle." [GOC:mah] synonym: "clathrin coat of endocytotic vesicle" EXACT [] xref: GO:0030128 is_a: CCO:C0000970 ! clathrin vesicle coat relationship: part_of CCO:C0001033 ! clathrin-coated endocytic vesicle membrane [Term] id: CCO:C0000974 name: clathrin coat of synaptic vesicle namespace: cellular_component def: "A clathrin coat found on a synaptic vesicle." [GOC:mah] xref: GO:0030129 is_a: CCO:C0000970 ! clathrin vesicle coat relationship: part_of CCO:C0001036 ! synaptic vesicle membrane [Term] id: CCO:C0000975 name: clathrin coat of trans-Golgi network vesicle namespace: cellular_component def: "A clathrin coat found on a vesicle of the trans-Golgi network." [GOC:mah] synonym: "clathrin coat of TGN vesicle" EXACT [] xref: GO:0030130 is_a: CCO:C0000970 ! clathrin vesicle coat is_a: CCO:C0001850 ! Golgi apparatus part relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0011260 ! CLH2_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0062915 ! NCALD_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063531 ! CLCB_HUMAN relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: part_of CCO:C0000738 ! trans-Golgi network transport vesicle membrane [Term] id: CCO:C0000976 name: clathrin adaptor complex namespace: cellular_component def: "A membrane coat adaptor complex that links clathrin to a membrane." [GOC:mah] xref: GO:0030131 is_a: CCO:C0000964 ! AP-type membrane coat adaptor complex relationship: location_of CCO:B0005197 ! AP2B1_HUMAN relationship: location_of CCO:B0005200 ! GGA2_HUMAN relationship: location_of CCO:B0005930 ! GGA3_HUMAN relationship: location_of CCO:B0011931 ! GGA1_HUMAN-Phosphoserine355 relationship: location_of CCO:B0057021 ! Q6ZNF7_HUMAN relationship: location_of CCO:B0058016 ! STON2_HUMAN relationship: location_of CCO:B0059412 ! STON1_HUMAN relationship: location_of CCO:B0062824 ! AP2M1_HUMAN relationship: location_of CCO:B0063204 ! AP1B1_HUMAN relationship: location_of CCO:B0065658 ! AP1M1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: part_of CCO:C0000963 ! clathrin coat [Term] id: CCO:C0000977 name: clathrin coat of coated pit namespace: cellular_component def: "The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex." [GOC:mah] xref: GO:0030132 is_a: CCO:C0000963 ! clathrin coat is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0011260 ! CLH2_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0062824 ! AP2M1_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063531 ! CLCB_HUMAN relationship: part_of CCO:C0000462 ! coated pit [Term] id: CCO:C0000978 name: transport vesicle namespace: cellular_component def: "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, and to destinations within or outside the cell." [GOC:mah] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'. synonym: "Golgi to plasma membrane transport vesicle" NARROW [] synonym: "Golgi to vacuole transport vesicle" NARROW [] synonym: "Golgi-plasma membrane transport vesicle" NARROW [] synonym: "Golgi-vacuole transport vesicle" NARROW [] synonym: "secretory vesicle" BROAD [] xref: GO:0030133 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: location_of CCO:B0005194 ! PKHF2_HUMAN relationship: location_of CCO:B0006287 ! ERG28_HUMAN relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0058000 ! APH1B_HUMAN relationship: location_of CCO:B0058066 ! AP3S1_HUMAN [Term] id: CCO:C0000979 name: ER to Golgi transport vesicle namespace: cellular_component def: "A vesicle that mediates transport from the endoplasmic reticulum to the Golgi complex; bears a coat formed of the COPII coat complex proteins; such vesicles found associated with endoplasmic reticulum (ER) membranes at steady state, and are involved in ER to Golgi (anterograde) vesicle transport." [GOC:mah, PMID:11252894] synonym: "COPII vesicle" RELATED [] synonym: "COPII-coated vesicle" EXACT [] synonym: "endoplasmic reticulum to Golgi transport vesicle" EXACT [] synonym: "endoplasmic reticulum-Golgi transport vesicle" EXACT [] synonym: "ER-Golgi transport vesicle" EXACT [] xref: GO:0030134 xref: GO:0030138 is_a: CCO:C0000379 ! Golgi-associated vesicle is_a: CCO:C0000978 ! transport vesicle is_a: CCO:C0000980 ! coated vesicle [Term] id: CCO:C0000980 name: coated vesicle namespace: cellular_component def: "Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins." [ISBN:0815316194] xref: GO:0005909 xref: GO:0030135 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0000981 name: clathrin-coated vesicle namespace: cellular_component def: "A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes." [GOC:mah, PMID:11252894] xref: GO:0030136 is_a: CCO:C0000980 ! coated vesicle relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0062929 ! MALL_HUMAN [Term] id: CCO:C0000982 name: COPI-coated vesicle namespace: cellular_component def: "A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport." [GOC:mah, PMID:11252894] synonym: "coatomer" RELATED [] xref: GO:0030137 is_a: CCO:C0000379 ! Golgi-associated vesicle is_a: CCO:C0000980 ! coated vesicle [Term] id: CCO:C0000983 name: endocytic vesicle namespace: cellular_component def: "A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance." [GOC:go_curators] subset: gosubset_prok synonym: "endocytotic transport vesicle" EXACT [] synonym: "endocytotic vesicle" EXACT [] xref: GO:0030139 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0023550 ! RAB5C_HUMAN relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0028600 ! APOA1_HUMAN relationship: location_of CCO:B0031341 ! MTSS1_HUMAN-Phosphotyrosine526 relationship: location_of CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0055282 ! SFTPD_HUMAN relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0067777 ! LRP2_HUMAN-Phosphoserine4463 relationship: location_of CCO:B0071536 ! TRFE_HUMAN-Omega-N-methylated arginine42 [Term] id: CCO:C0000984 name: trans-Golgi network transport vesicle namespace: cellular_component def: "A vesicle that mediates transport between the trans-Golgi network and other parts of the cell." [GOC:mah] synonym: "TGN transport vesicle" EXACT [] xref: GO:0030140 is_a: CCO:C0000379 ! Golgi-associated vesicle is_a: CCO:C0000978 ! transport vesicle is_a: CCO:C0000981 ! clathrin-coated vesicle relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0054994 ! MPRI_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058995 ! SPG21_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0066303 ! FURIN_HUMAN-Phosphoserine773 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 [Term] id: CCO:C0000985 name: secretory granule namespace: cellular_component def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198596732] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'. synonym: "secretory vesicle" BROAD [] xref: GO:0030141 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle relationship: location_of CCO:B0001471 ! TGFB1_HUMAN relationship: location_of CCO:B0001649 ! BRCA2_HUMAN relationship: location_of CCO:B0002164 ! GKN1_HUMAN relationship: location_of CCO:B0034532 ! AMD_HUMAN-Phosphoserine955 relationship: location_of CCO:B0037954 ! 7B2_HUMAN relationship: location_of CCO:B0039662 ! SYG_HUMAN-Phosphotyrosine453 relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0057369 ! SACA3_HUMAN relationship: location_of CCO:B0057884 ! ANGL6_HUMAN relationship: location_of CCO:B0059139 ! PCSK1_HUMAN relationship: location_of CCO:B0066362 ! GALA_HUMAN-Phosphoserine117 relationship: location_of CCO:B0069683 ! RAB3B_HUMAN-Cysteine methyl ester219 [Term] id: CCO:C0000986 name: Golgi to ER transport vesicle namespace: cellular_component def: "A vesicle that mediates transport from the Golgi to the endoplasmic reticulum." [GOC:mah] synonym: "Golgi to endoplasmic reticulum transport vesicle" EXACT [] synonym: "Golgi-endoplasmic reticulum transport vesicle" EXACT [] synonym: "Golgi-ER transport vesicle" EXACT [] xref: GO:0030142 is_a: CCO:C0000978 ! transport vesicle is_a: CCO:C0000982 ! COPI-coated vesicle [Term] id: CCO:C0000987 name: inter-Golgi transport vesicle namespace: cellular_component def: "A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack)." [GOC:mah] xref: GO:0005807 xref: GO:0030143 is_a: CCO:C0000978 ! transport vesicle is_a: CCO:C0000982 ! COPI-coated vesicle [Term] id: CCO:C0000988 name: integral to Golgi membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the Golgi complex membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:go_curators] synonym: "Golgi integral membrane protein" RELATED [] xref: GO:0030173 is_a: CCO:C0001152 ! intrinsic to Golgi membrane is_a: CCO:C0001188 ! integral to organelle membrane relationship: location_of CCO:B0057878 ! B4GN2_HUMAN relationship: location_of CCO:B0057945 ! CGAT1_HUMAN relationship: location_of CCO:B0063311 ! SMS1_HUMAN relationship: location_of CCO:B0063336 ! SIA7F_HUMAN relationship: location_of CCO:B0063432 ! RER1_HUMAN [Term] id: CCO:C0000989 name: filopodium namespace: cellular_component def: "Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward." [GOC:mah, ISBN:0815316194] subset: goslim_pir synonym: "microspike" EXACT [] xref: GO:0030028 xref: GO:0030175 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0005338 ! CDC42_HUMAN relationship: location_of CCO:B0005642 ! ACTN2_HUMAN relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0033364 ! RUFY3_HUMAN relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0038095 ! ABI2_HUMAN relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0057306 ! PDPN_HUMAN relationship: location_of CCO:B0066143 ! FAT1_HUMAN-Phosphoserine2611 relationship: location_of CCO:B0066287 ! FSCN1_HUMAN-Phosphoserine39 [Term] id: CCO:C0000990 name: integral to endoplasmic reticulum membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] synonym: "ER integral membrane protein" EXACT [] synonym: "integral to ER membrane" EXACT [] xref: GO:0030176 is_a: CCO:C0001151 ! intrinsic to endoplasmic reticulum membrane is_a: CCO:C0001188 ! integral to organelle membrane relationship: location_of CCO:B0001428 ! ERN1_HUMAN relationship: location_of CCO:B0001818 ! EXT1_HUMAN relationship: location_of CCO:B0002135 ! PIGU_HUMAN relationship: location_of CCO:B0039642 ! RRBP1_HUMAN-Phosphothreonine255 relationship: location_of CCO:B0043374 ! RTN4_HUMAN-Phosphoserine863 relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0055978 ! FKBP8_HUMAN relationship: location_of CCO:B0058351 ! DERL3_HUMAN relationship: location_of CCO:B0058480 ! SELS_HUMAN relationship: location_of CCO:B0058631 ! DERL2_HUMAN relationship: location_of CCO:B0059206 ! AMFR2_HUMAN relationship: location_of CCO:B0064741 ! DERL1_HUMAN-Phosphothreonine202 relationship: location_of CCO:B0070259 ! RTN1_HUMAN-Phosphoserine487 relationship: location_of CCO:B0070260 ! RTN2_HUMAN-Phosphoserine44 relationship: location_of CCO:B0071842 ! WFS1_HUMAN-Phosphoserine32 [Term] id: CCO:C0000991 name: insulin control element activator complex namespace: cellular_component def: "Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription." [PMID:7935390] synonym: "ICE activator complex" EXACT [] xref: GO:0030232 is_a: CCO:C0000272 ! transcription factor complex relationship: location_of CCO:B0056128 ! Q16219_HUMAN [Term] id: CCO:C0000992 name: type I protein secretion system complex namespace: cellular_component def: "A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space." [PMID:9618447] subset: gosubset_prok synonym: "ABC translocator complex" BROAD [] xref: GO:0030256 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000993 name: type III protein secretion system complex namespace: cellular_component def: "A complex of approximately 20 proteins, most of which are located in the inner membrane that carries out protein secretion in the type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase." [PMID:9618447] subset: gosubset_prok synonym: "T3SS complex" EXACT [] synonym: "TTSS complex" EXACT [] xref: GO:0030257 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0000994 name: integral to synaptic vesicle membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a synaptic vesicle membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:go_curators] xref: GO:0030285 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: location_of CCO:B0022924 ! GBRA2_HUMAN relationship: part_of CCO:C0001036 ! synaptic vesicle membrane [Term] id: CCO:C0000995 name: dynein complex namespace: cellular_component def: "Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity." [ISBN:0815316194] xref: GO:0030286 is_a: CCO:C0000435 ! microtubule associated complex relationship: location_of CCO:B0001780 ! DYHC1_HUMAN relationship: location_of CCO:B0005562 ! DLRB1_HUMAN relationship: location_of CCO:B0006028 ! DYH9_HUMAN relationship: location_of CCO:B0006226 ! DYL1_HUMAN relationship: location_of CCO:B0011441 ! DC1I1_HUMAN-Phosphoserine635 relationship: location_of CCO:B0011452 ! DCTN1_HUMAN-Phosphoserine541 relationship: location_of CCO:B0055823 ! DYH14_HUMAN relationship: location_of CCO:B0058028 ! DYH12_HUMAN relationship: location_of CCO:B0062812 ! DYL2_HUMAN relationship: location_of CCO:B0063409 ! DC1L2_HUMAN [Term] id: CCO:C0000996 name: cell wall-bounded periplasmic space namespace: cellular_component def: "The region between the plasma membrane and the cell wall as found in organisms such as yeast and Gram positive bacteria. These periplasmic spaces are quite thin." [GOC:mlg, GOC:mtg_sensu] subset: gosubset_prok synonym: "cell wall bounded periplasmic space" EXACT [] synonym: "cell wall-enclosed periplasmic space" EXACT [] synonym: "periplasmic space (sensu Fungi)" NARROW [] xref: GO:0030287 is_a: CCO:C0001662 ! periplasmic space [Term] id: CCO:C0000997 name: outer membrane-bounded periplasmic space namespace: cellular_component def: "The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin cell wall." [GOC:mlg, GOC:mtg_sensu] subset: gosubset_prok synonym: "outer membrane bounded periplasmic space" EXACT [] synonym: "outer membrane-enclosed periplasmic space" EXACT [] synonym: "periplasmic space (sensu Gram-negative Bacteria)" EXACT [] synonym: "periplasmic space (sensu Proteobacteria)" EXACT [] xref: GO:0030288 is_a: CCO:C0001662 ! periplasmic space is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0001000 ! cell envelope [Term] id: CCO:C0000998 name: protein phosphatase 4 complex namespace: cellular_component def: "The complex formed by the catalytic subunit of protein phosphatase 4 plus a regulatory subunit." [PMID:10026142] xref: GO:0030289 is_a: CCO:C0000541 ! protein serine/threonine phosphatase complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0000999 name: external encapsulating structure namespace: cellular_component def: "A structure that lies outside the plasma membrane and surrounds the entire cell." [GOC:go_curators] subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: gosubset_prok xref: GO:0030312 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001000 name: cell envelope namespace: cellular_component def: "Everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present." [GOC:jl, http://pathmicro.med.sc.edu/fox/cell_envelope.htm] subset: goslim_generic subset: goslim_pir subset: gosubset_prok xref: GO:0030313 is_a: CCO:C0000999 ! external encapsulating structure is_a: CCO:C0001367 ! envelope [Term] id: CCO:C0001001 name: junctional membrane complex namespace: cellular_component def: "Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules)." [PMID:11535622] synonym: "triad junction" BROAD [] xref: GO:0030314 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: part_of CCO:C0000801 ! sarcoplasm [Term] id: CCO:C0001002 name: T-tubule namespace: cellular_component def: "Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane." [GOC:mtg_muscle, ISBN:0815316194] synonym: "transverse tubule" EXACT [] synonym: "triad" RELATED [] xref: GO:0030315 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: part_of CCO:C0001638 ! sarcolemma [Term] id: CCO:C0001003 name: ferredoxin:thioredoxin reductase complex namespace: cellular_component def: "A protein complex that possesses ferredoxin:thioredoxin reductase activity." [GOC:mah] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'ferredoxin:thioredoxin reductase activity ; GO:0030385'. xref: GO:0030386 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0001004 name: axon namespace: cellular_component def: "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." [GOC:nln, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030424 is_a: CCO:C0001707 ! neuron projection relationship: location_of CCO:B0001471 ! TGFB1_HUMAN relationship: location_of CCO:B0001687 ! TGFB2_HUMAN relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0013172 ! NFL_HUMAN-Phosphoserine472 relationship: location_of CCO:B0026382 ! NF1_HUMAN-Phosphoserine2829 relationship: location_of CCO:B0033567 ! GHRL_HUMAN relationship: location_of CCO:B0035998 ! DCC_HUMAN-Phosphothreonine1074 relationship: location_of CCO:B0042239 ! GRM2_HUMAN relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0054845 ! CALC_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0057365 ! CNTN4_HUMAN relationship: location_of CCO:B0058685 ! SEM6A_HUMAN relationship: location_of CCO:B0062861 ! NCS1_HUMAN relationship: location_of CCO:B0064111 ! CCKN_HUMAN-Sulfotyrosine97 relationship: location_of CCO:B0064831 ! DOCK7_HUMAN-Phosphoserine1432 relationship: location_of CCO:B0064869 ! DPYL2_HUMAN-Phosphoserine518 relationship: location_of CCO:B0064890 ! DTBP1_HUMAN-Phosphoserine321 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0068321 ! MTPN_HUMAN-N-acetylcysteine2 relationship: location_of CCO:B0068681 ! NFM_HUMAN-Phosphoserine654 relationship: location_of CCO:B0070613 ! SMBP2_HUMAN-Phosphoserine656 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 [Term] id: CCO:C0001005 name: dendrite namespace: cellular_component def: "A branching protoplasmic process of a neuron that receive and integrate signals coming from axons of other neurons, and convey the resulting signal to the body of the cell." [GOC:nln, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030425 is_a: CCO:C0001707 ! neuron projection relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0005816 ! ATX10_HUMAN relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0013718 ! RB27A_HUMAN-Cysteine methyl ester221 relationship: location_of CCO:B0015673 ! CHL1_HUMAN relationship: location_of CCO:B0026382 ! NF1_HUMAN-Phosphoserine2829 relationship: location_of CCO:B0035064 ! KPCG_HUMAN-Phosphoserine687 relationship: location_of CCO:B0054545 ! OPA1_HUMAN relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0055198 ! 5HT2A_HUMAN relationship: location_of CCO:B0058468 ! DPYL5_HUMAN relationship: location_of CCO:B0062861 ! NCS1_HUMAN relationship: location_of CCO:B0064792 ! DNER_HUMAN-Phosphotyrosine718 relationship: location_of CCO:B0064869 ! DPYL2_HUMAN-Phosphoserine518 relationship: location_of CCO:B0064879 ! DREB_HUMAN-Phosphothreonine331 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0071842 ! WFS1_HUMAN-Phosphoserine32 [Term] id: CCO:C0001006 name: growth cone namespace: cellular_component def: "The migrating motile tip of a growing nerve cell axon or dendrite." [ISBN:0815316194] xref: GO:0030426 is_a: CCO:C0001007 ! site of polarized growth relationship: location_of CCO:B0001344 ! APBB1_HUMAN relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0001998 ! Q8TEY4_HUMAN relationship: location_of CCO:B0002020 ! APBB2_HUMAN relationship: location_of CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0025035 ! Q7Z324_HUMAN relationship: location_of CCO:B0033364 ! RUFY3_HUMAN relationship: location_of CCO:B0035712 ! STMN2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0055255 ! OTX2_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055954 ! RGRF1_HUMAN relationship: location_of CCO:B0056401 ! Q59GA0_HUMAN relationship: location_of CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: location_of CCO:B0064831 ! DOCK7_HUMAN-Phosphoserine1432 relationship: location_of CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 [Term] id: CCO:C0001007 name: site of polarized growth namespace: cellular_component def: "Any part of a cell where non-isotropic growth takes place." [GOC:mah] subset: goslim_candida subset: goslim_pir subset: goslim_yeast synonym: "site of polarized growth (sensu Fungi)" EXACT [] synonym: "site of polarized growth (sensu Saccharomyces)" EXACT [] xref: GO:0000134 xref: GO:0030427 xref: GO:0030483 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001008 name: cell septum namespace: cellular_component def: "A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells." [GOC:clt, ISBN:0471940526] subset: goslim_pir subset: gosubset_prok synonym: "cross wall" EXACT [] synonym: "septum" BROAD [] xref: GO:0030428 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001009 name: host cell cytoplasm namespace: cellular_component def: "The cytoplasm of a host cell." [GOC:mah] subset: gosubset_prok xref: GO:0030430 is_a: CCO:C0001591 ! host intracellular part relationship: part_of CCO:C0001803 ! intracellular region of host [Term] id: CCO:C0001010 name: yeast-form cell wall namespace: cellular_component def: "The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form." [GOC:mah, GOC:mcc] comment: See also the Fungal Anatomy Ontology term 'vegetative cell ; FAO:0000032'. xref: GO:0030445 is_a: CCO:C0002066 ! fungal-type cell wall [Term] id: CCO:C0001011 name: hyphal cell wall namespace: cellular_component def: "The cell wall surrounding a fungal hypha." [GOC:mah] comment: See also the Fungal Anatomy Ontology term 'hypha ; FAO:0001001'. xref: GO:0030446 is_a: CCO:C0002066 ! fungal-type cell wall [Term] id: CCO:C0001012 name: actin cap namespace: cellular_component def: "Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell." [GOC:mah, ISBN:10652251] synonym: "actin cap (sensu Fungi)" EXACT [] synonym: "actin cap (sensu Saccharomyces)" NARROW [] xref: GO:0000143 xref: GO:0030478 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001867 ! cell cortex part relationship: part_of CCO:C0001056 ! cortical actin cytoskeleton [Term] id: CCO:C0001013 name: actin cortical patch namespace: cellular_component def: "Discrete actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751)." [GOC:mah, ISBN:0879693568, ISBN:0879693649, Sanger:wv] synonym: "actin cortical patch (sensu Fungi)" EXACT [] synonym: "actin cortical patch (sensu Saccharomyces)" NARROW [] synonym: "actin patch" EXACT [] xref: GO:0005857 xref: GO:0030479 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001867 ! cell cortex part relationship: part_of CCO:C0001056 ! cortical actin cytoskeleton [Term] id: CCO:C0001014 name: actin cable namespace: cellular_component def: "A long bundle of actin filaments, comprising filamentous actin and associated proteins, found in cells." [ISBN:0879693649] synonym: "actin cable (sensu Fungi)" EXACT [] synonym: "actin cable (sensu Saccharomyces)" EXACT [] xref: GO:0000141 xref: GO:0030482 is_a: CCO:C0001449 ! actin filament bundle [Term] id: CCO:C0001015 name: smooth muscle contractile fiber namespace: cellular_component def: "The contractile fiber of smooth muscle cells." [GOC:mah] synonym: "smooth muscle fiber" BROAD [] synonym: "smooth muscle fibre" EXACT [] xref: GO:0030485 is_a: CCO:C0001766 ! contractile fiber is_a: CCO:C0001868 ! contractile fiber part [Term] id: CCO:C0001016 name: smooth muscle dense body namespace: cellular_component def: "Electron-dense region associated with a smooth muscle contractile fiber." [GOC:mah, ISBN:0815316194] xref: GO:0030486 is_a: CCO:C0001868 ! contractile fiber part relationship: part_of CCO:C0001015 ! smooth muscle contractile fiber [Term] id: CCO:C0001017 name: midbody namespace: cellular_component def: "A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis." [ISBN:0815316194] subset: goslim_pir xref: GO:0030496 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0002238 ! MARE3_HUMAN relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010723 ! AURKB_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0011078 ! CDC2_HUMAN-Phosphothreonine14 relationship: location_of CCO:B0032855 ! MYH10_HUMAN-Phosphothreonine1960 relationship: location_of CCO:B0048362 ! PSRC1_HUMAN-Phosphothreonine245 relationship: location_of CCO:B0055261 ! STX2_HUMAN relationship: location_of CCO:B0058166 ! ARL8A_HUMAN relationship: location_of CCO:B0063163 ! ZN330_HUMAN [Term] id: CCO:C0001018 name: granulocyte macrophage colony-stimulating factor receptor complex namespace: cellular_component def: "The heterodimeric receptor for granulocyte macrophage colony-stimulating factor." [GOC:mah] xref: GO:0030526 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0034872 ! IL3RB_HUMAN-Phosphotyrosine766 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001019 name: ribonucleoprotein complex namespace: cellular_component def: "A macromolecular complex containing both protein and RNA molecules." [GOC:krc] subset: goslim_pir subset: gosubset_prok synonym: "protein-RNA complex" EXACT [] synonym: "ribonucleoprotein" EXACT [] synonym: "RNA-protein complex" EXACT [] synonym: "RNP" EXACT [] xref: GO:0030529 is_a: CCO:C0001492 ! macromolecular complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001676 ! NH2L1_HUMAN relationship: location_of CCO:B0001691 ! RS4X_HUMAN relationship: location_of CCO:B0001952 ! RM41_HUMAN relationship: location_of CCO:B0005349 ! LSM8_HUMAN relationship: location_of CCO:B0005494 ! LSM7_HUMAN relationship: location_of CCO:B0005495 ! RUXG_HUMAN relationship: location_of CCO:B0005567 ! LSM6_HUMAN relationship: location_of CCO:B0005725 ! ROA2_HUMAN relationship: location_of CCO:B0005744 ! RS19_HUMAN relationship: location_of CCO:B0005746 ! RL7_HUMAN relationship: location_of CCO:B0005750 ! RS9_HUMAN relationship: location_of CCO:B0005751 ! RL22_HUMAN relationship: location_of CCO:B0005761 ! RL7A_HUMAN relationship: location_of CCO:B0005767 ! RS12_HUMAN relationship: location_of CCO:B0005768 ! RS3A_HUMAN relationship: location_of CCO:B0005776 ! RSSA_HUMAN relationship: location_of CCO:B0005855 ! RL12_HUMAN relationship: location_of CCO:B0005857 ! RL15_HUMAN relationship: location_of CCO:B0005858 ! RL11_HUMAN relationship: location_of CCO:B0005859 ! RL27_HUMAN relationship: location_of CCO:B0005860 ! RL8_HUMAN relationship: location_of CCO:B0005861 ! RL4_HUMAN relationship: location_of CCO:B0006005 ! LSM1_HUMAN relationship: location_of CCO:B0006095 ! RT12_HUMAN relationship: location_of CCO:B0006111 ! RSMN_HUMAN relationship: location_of CCO:B0006208 ! RT06_HUMAN relationship: location_of CCO:B0006231 ! RL37A_HUMAN relationship: location_of CCO:B0006248 ! RM20_HUMAN relationship: location_of CCO:B0006275 ! HNRPL_HUMAN relationship: location_of CCO:B0006288 ! RT26_HUMAN relationship: location_of CCO:B0006313 ! SRPRB_HUMAN relationship: location_of CCO:B0011131 ! CELF1_HUMAN-Phosphoserine302 relationship: location_of CCO:B0011519 ! DKC1_HUMAN-Phosphoserine513 relationship: location_of CCO:B0011857 ! FBRL_HUMAN-Asymmetric dimethylarginine36 relationship: location_of CCO:B0012209 ! HNRH3_HUMAN-Asymmetric dimethylarginine121 relationship: location_of CCO:B0012223 ! HNRPD_HUMAN-Phosphoserine82 relationship: location_of CCO:B0012231 ! HNRPF_HUMAN-Phosphoserine161 relationship: location_of CCO:B0012250 ! HNRPK_HUMAN-Omega-N-methylated arginine296 relationship: location_of CCO:B0012707 ! LSM3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013366 ! PA2G4_HUMAN-Phosphoserine2 relationship: location_of CCO:B0013882 ! RL12_HUMAN-Phosphoserine38 relationship: location_of CCO:B0013884 ! RL18A_HUMAN-Phosphotyrosine63 relationship: location_of CCO:B0013886 ! RL18_HUMAN-Phosphoserine130 relationship: location_of CCO:B0013888 ! RL24_HUMAN-Phosphoserine86 relationship: location_of CCO:B0013889 ! RL28_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013896 ! RLA0_HUMAN-Phosphotyrosine24 relationship: location_of CCO:B0013900 ! RLA1_HUMAN-Phosphotyrosine11 relationship: location_of CCO:B0013905 ! RLA2_HUMAN-Phosphoserine102 relationship: location_of CCO:B0013910 ! ROA1_HUMAN-Phosphoserine4 relationship: location_of CCO:B0013926 ! ROA2_HUMAN-Phosphoserine259 relationship: location_of CCO:B0013932 ! RS10_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0013936 ! RS13_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013939 ! RS20_HUMAN-Phosphothreonine9 relationship: location_of CCO:B0013940 ! RS24_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013943 ! RS7_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0023192 ! SMD1_HUMAN relationship: location_of CCO:B0029592 ! RL36_HUMAN relationship: location_of CCO:B0030465 ! RS23_HUMAN relationship: location_of CCO:B0033001 ! RS27_HUMAN relationship: location_of CCO:B0033633 ! RL13_HUMAN relationship: location_of CCO:B0034271 ! RS25_HUMAN relationship: location_of CCO:B0035344 ! PCBP1_HUMAN-Phosphoserine190 relationship: location_of CCO:B0035500 ! RALY_HUMAN-Phosphoserine135 relationship: location_of CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: location_of CCO:B0036028 ! RL21_HUMAN-Phosphothreonine47 relationship: location_of CCO:B0040516 ! RS14_HUMAN relationship: location_of CCO:B0043438 ! RUXF_HUMAN relationship: location_of CCO:B0043446 ! RM10_HUMAN relationship: location_of CCO:B0043492 ! RSMB_HUMAN-Omega-N-methylated arginine112 relationship: location_of CCO:B0043592 ! RL23_HUMAN relationship: location_of CCO:B0043825 ! RS15A_HUMAN relationship: location_of CCO:B0048277 ! HNRPC_HUMAN-Phosphoserine306 relationship: location_of CCO:B0051562 ! SRP09_HUMAN relationship: location_of CCO:B0052695 ! ROA0_HUMAN-Phosphoserine84 relationship: location_of CCO:B0052699 ! ROA3_HUMAN-Phosphoserine355 relationship: location_of CCO:B0055316 ! SRP14_HUMAN relationship: location_of CCO:B0055464 ! RT29_HUMAN relationship: location_of CCO:B0055501 ! RM12_HUMAN relationship: location_of CCO:B0055717 ! RL6_HUMAN relationship: location_of CCO:B0055871 ! RM28_HUMAN relationship: location_of CCO:B0062848 ! NO40_HUMAN relationship: location_of CCO:B0062872 ! IMP3_HUMAN relationship: location_of CCO:B0062885 ! RL9_HUMAN relationship: location_of CCO:B0062892 ! RO52_HUMAN relationship: location_of CCO:B0062930 ! RT18B_HUMAN relationship: location_of CCO:B0063003 ! SNRPA_HUMAN relationship: location_of CCO:B0063048 ! RL35A_HUMAN relationship: location_of CCO:B0063050 ! RLA0L_HUMAN relationship: location_of CCO:B0063061 ! RS5_HUMAN relationship: location_of CCO:B0063078 ! RS16_HUMAN relationship: location_of CCO:B0063083 ! RL3_HUMAN relationship: location_of CCO:B0063091 ! RL35_HUMAN relationship: location_of CCO:B0063093 ! RL10_HUMAN relationship: location_of CCO:B0063157 ! LSM4_HUMAN relationship: location_of CCO:B0063217 ! M11D1_HUMAN relationship: location_of CCO:B0063353 ! RS26_HUMAN relationship: location_of CCO:B0063356 ! RL27A_HUMAN relationship: location_of CCO:B0063360 ! RL23A_HUMAN relationship: location_of CCO:B0063368 ! RS28_HUMAN relationship: location_of CCO:B0063382 ! HNRPR_HUMAN relationship: location_of CCO:B0063385 ! RM44_HUMAN relationship: location_of CCO:B0063466 ! RT31_HUMAN relationship: location_of CCO:B0063474 ! RS2_HUMAN relationship: location_of CCO:B0063523 ! RM38_HUMAN relationship: location_of CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 relationship: location_of CCO:B0065820 ! CASC3_HUMAN-Phosphoserine363 relationship: location_of CCO:B0066854 ! HNRH1_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0066856 ! HNRH2_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0066860 ! HNRL1_HUMAN-Phosphoserine512 relationship: location_of CCO:B0066865 ! HNRPG_HUMAN-Phosphoserine326 relationship: location_of CCO:B0066869 ! HNRPM_HUMAN-Phosphoserine432 relationship: location_of CCO:B0066887 ! HNRPU_HUMAN-Omega-N-methylated arginine732 relationship: location_of CCO:B0067447 ! KRR1_HUMAN-Phosphothreonine337 relationship: location_of CCO:B0067787 ! LSM2_HUMAN-Phosphothreonine79 relationship: location_of CCO:B0069621 ! PUF60_HUMAN-Phosphothreonine60 relationship: location_of CCO:B0069784 ! RBM14_HUMAN-Phosphothreonine572 relationship: location_of CCO:B0070063 ! RL14_HUMAN-Phosphoserine139 relationship: location_of CCO:B0070079 ! RL26_HUMAN-Phosphothreonine139 relationship: location_of CCO:B0070080 ! RL29_HUMAN-N6-methyllysine5 relationship: location_of CCO:B0070084 ! RL31_HUMAN-Phosphotyrosine108 relationship: location_of CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 relationship: location_of CCO:B0070200 ! RS11_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 relationship: location_of CCO:B0070222 ! RS8_HUMAN-Phosphothreonine130 relationship: location_of CCO:B0070251 ! RT09_HUMAN-Phosphotyrosine262 relationship: location_of CCO:B0070262 ! RU17_HUMAN-Phosphotyrosine126 relationship: location_of CCO:B0070268 ! RU2A_HUMAN-Phosphoserine197 relationship: location_of CCO:B0070644 ! SMD2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0070862 ! SRA1_HUMAN-Phosphothreonine68 relationship: location_of CCO:B0071342 ! TERT_HUMAN-Phosphothreonine1113 [Term] id: CCO:C0001020 name: heterogeneous nuclear ribonucleoprotein complex namespace: cellular_component def: "Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "heterogeneous nuclear ribonucleoprotein" EXACT [] synonym: "hnRNP" EXACT [] xref: GO:0030530 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0012209 ! HNRH3_HUMAN-Asymmetric dimethylarginine121 relationship: location_of CCO:B0012223 ! HNRPD_HUMAN-Phosphoserine82 relationship: location_of CCO:B0012231 ! HNRPF_HUMAN-Phosphoserine161 relationship: location_of CCO:B0012250 ! HNRPK_HUMAN-Omega-N-methylated arginine296 relationship: location_of CCO:B0013910 ! ROA1_HUMAN-Phosphoserine4 relationship: location_of CCO:B0013926 ! ROA2_HUMAN-Phosphoserine259 relationship: location_of CCO:B0035500 ! RALY_HUMAN-Phosphoserine135 relationship: location_of CCO:B0039600 ! PTBP1_HUMAN-Phosphoserine141 relationship: location_of CCO:B0052695 ! ROA0_HUMAN-Phosphoserine84 relationship: location_of CCO:B0054395 ! HNRDL_HUMAN relationship: location_of CCO:B0063382 ! HNRPR_HUMAN relationship: location_of CCO:B0066854 ! HNRH1_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0066856 ! HNRH2_HUMAN-Phosphothreonine107 relationship: location_of CCO:B0066860 ! HNRL1_HUMAN-Phosphoserine512 relationship: location_of CCO:B0066865 ! HNRPG_HUMAN-Phosphoserine326 relationship: location_of CCO:B0066887 ! HNRPU_HUMAN-Omega-N-methylated arginine732 [Term] id: CCO:C0001021 name: small cytoplasmic ribonucleoprotein complex namespace: cellular_component def: "A complex composed of RNA of the small cytoplasmic RNA (scRNA) class and protein, found in the cytoplasm." [GOC:krc, GOC:mah] synonym: "scRNP" EXACT [] synonym: "small cytoplasmic ribonucleoprotein" EXACT [] xref: GO:0030531 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001022 name: small nuclear ribonucleoprotein complex namespace: cellular_component def: "A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs." [GOC:krc, GOC:mah, ISBN:0879695897] subset: goslim_pir synonym: "small nuclear ribonucleoprotein" EXACT [] synonym: "snRNP" EXACT [] xref: GO:0030532 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0005495 ! RUXG_HUMAN relationship: location_of CCO:B0005567 ! LSM6_HUMAN relationship: location_of CCO:B0006111 ! RSMN_HUMAN relationship: location_of CCO:B0023192 ! SMD1_HUMAN relationship: location_of CCO:B0026181 ! SF3B3_HUMAN relationship: location_of CCO:B0043438 ! RUXF_HUMAN relationship: location_of CCO:B0043492 ! RSMB_HUMAN-Omega-N-methylated arginine112 relationship: location_of CCO:B0063157 ! LSM4_HUMAN relationship: location_of CCO:B0066441 ! GEMI4_HUMAN-Phosphoserine205 relationship: location_of CCO:B0070268 ! RU2A_HUMAN-Phosphoserine197 relationship: location_of CCO:B0070644 ! SMD2_HUMAN-N-acetylserine2 [Term] id: CCO:C0001023 name: transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a transport vesicle." [GOC:mah] synonym: "secretory vesicle membrane" BROAD [] xref: GO:0030658 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0000978 ! transport vesicle [Term] id: CCO:C0001024 name: cytoplasmic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a cytoplasmic vesicle." [GOC:mah] xref: GO:0030659 is_a: CCO:C0000734 ! vesicle membrane is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011260 ! CLH2_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0019513 ! TAOK2_HUMAN relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0057324 ! ZDH17_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058066 ! AP3S1_HUMAN relationship: location_of CCO:B0058996 ! GPC5B_HUMAN relationship: location_of CCO:B0059328 ! NSG2_HUMAN relationship: location_of CCO:B0062957 ! PHLA1_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063531 ! CLCB_HUMAN relationship: location_of CCO:B0065817 ! CALY_HUMAN-Phosphotyrosine151 relationship: location_of CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 relationship: location_of CCO:B0069665 ! RAB13_HUMAN-Phosphoserine178 relationship: location_of CCO:B0069720 ! RAI3_HUMAN-Phosphotyrosine347 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0071730 ! ULK1_HUMAN-Phosphothreonine625 relationship: part_of CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0001025 name: Golgi-associated vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." [GOC:mah] synonym: "Golgi vesicle membrane" RELATED [] xref: GO:0030660 is_a: CCO:C0000021 ! Golgi membrane is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: location_of CCO:B0043777 ! CXA1_HUMAN-Phosphothreonine326 relationship: location_of CCO:B0054734 ! CSPG5_HUMAN relationship: part_of CCO:C0000379 ! Golgi-associated vesicle [Term] id: CCO:C0001026 name: chitosome membrane namespace: cellular_component def: "The lipid bilayer surrounding a chitosome." [GOC:mah] xref: GO:0030661 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0001883 ! chitosome [Term] id: CCO:C0001027 name: coated vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a coated vesicle." [GOC:mah] xref: GO:0030662 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0000980 ! coated vesicle [Term] id: CCO:C0001028 name: COPI coated vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a COPI-coated vesicle." [GOC:mah] xref: GO:0030663 is_a: CCO:C0001025 ! Golgi-associated vesicle membrane is_a: CCO:C0001027 ! coated vesicle membrane relationship: part_of CCO:C0000982 ! COPI-coated vesicle [Term] id: CCO:C0001029 name: clathrin coated vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a clathrin-coated vesicle." [GOC:mah] xref: GO:0030665 is_a: CCO:C0001027 ! coated vesicle membrane relationship: part_of CCO:C0000981 ! clathrin-coated vesicle [Term] id: CCO:C0001030 name: endocytic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding an endocytic vesicle." [GOC:mah] xref: GO:0030666 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: part_of CCO:C0000983 ! endocytic vesicle [Term] id: CCO:C0001031 name: secretory granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a secretory granule." [GOC:mah] synonym: "secretory vesicle membrane" BROAD [] xref: GO:0030667 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0000985 ! secretory granule [Term] id: CCO:C0001032 name: merozoite dense granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites." [GOC:mah, GOC:mtg_sensu] synonym: "dense granule membrane (sensu Apicomplexa)" EXACT [] xref: GO:0030668 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0000922 ! merozoite dense granule [Term] id: CCO:C0001033 name: clathrin-coated endocytic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a clathrin-coated endocytic vesicle." [GOC:mah] xref: GO:0030669 is_a: CCO:C0001029 ! clathrin coated vesicle membrane is_a: CCO:C0001030 ! endocytic vesicle membrane relationship: location_of CCO:B0067608 ! LDLR_HUMAN-Phosphotyrosine845 relationship: part_of CCO:C0001949 ! clathrin-coated endocytic vesicle [Term] id: CCO:C0001034 name: phagocytic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a phagocytic vesicle." [GOC:mah] xref: GO:0030670 is_a: CCO:C0001030 ! endocytic vesicle membrane relationship: location_of CCO:B0002197 ! DMBT1_HUMAN relationship: part_of CCO:C0001950 ! phagocytic vesicle [Term] id: CCO:C0001035 name: clathrin-coated phagocytic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a clathrin-coated phagocytic vesicle." [GOC:mah] xref: GO:0030671 is_a: CCO:C0001033 ! clathrin-coated endocytic vesicle membrane is_a: CCO:C0001034 ! phagocytic vesicle membrane relationship: part_of CCO:C0001951 ! clathrin-coated phagocytic vesicle [Term] id: CCO:C0001036 name: synaptic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a synaptic vesicle." [GOC:mah] xref: GO:0030672 is_a: CCO:C0001029 ! clathrin coated vesicle membrane relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: part_of CCO:C0000522 ! synaptic vesicle [Term] id: CCO:C0001037 name: axolemma namespace: cellular_component def: "The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness." [http://www.medik.sk/clanky/bio_jun.htm, ISBN:0124325653] xref: GO:0030673 is_a: CCO:C0000766 ! membrane is_a: CCO:C0001469 ! neuron projection membrane is_a: CCO:C0001562 ! axon part [Term] id: CCO:C0001038 name: ribonuclease P complex namespace: cellular_component def: "A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs." [GOC:mah, PMID:12045094] comment: Note that chloroplasts possess a complex that is called 'RNase P' because it catalyzes pre-tRNA cleavage, but the chloroplast complex appears not to contain RNA. subset: goslim_pir subset: gosubset_prok synonym: "RNase P complex" EXACT [] xref: GO:0030677 is_a: CCO:C0001019 ! ribonucleoprotein complex [Term] id: CCO:C0001039 name: mitochondrial ribonuclease P complex namespace: cellular_component def: "A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species, but the complex often contains a single RNA molecule and a single protein molecule." [GOC:mah, PMID:12045094] synonym: "mitochondrial RNase P complex" EXACT [] xref: GO:0030678 is_a: CCO:C0001038 ! ribonuclease P complex is_a: CCO:C0001848 ! mitochondrial part [Term] id: CCO:C0001040 name: cyanelle ribonuclease P complex namespace: cellular_component def: "A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules." [GOC:mah, PMID:12045094] synonym: "cyanelle RNase P complex" EXACT [] xref: GO:0030679 is_a: CCO:C0001042 ! multimeric ribonuclease P complex is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000700 ! cyanelle [Term] id: CCO:C0001041 name: dimeric ribonuclease P complex namespace: cellular_component def: "A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule." [GOC:mah, PMID:12045094] subset: gosubset_prok synonym: "dimeric RNase P complex" EXACT [] synonym: "ribonuclease P complex (sensu Bacteria)" NARROW [] synonym: "RNase P complex (sensu Bacteria)" NARROW [] xref: GO:0030680 is_a: CCO:C0001038 ! ribonuclease P complex [Term] id: CCO:C0001042 name: multimeric ribonuclease P complex namespace: cellular_component def: "A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules." [GOC:mah, PMID:11142368, PMID:12045094] synonym: "multimeric RNase P complex" EXACT [] synonym: "ribonuclease P complex (sensu Archaea" NARROW [] synonym: "RNase P complex (sensu Archaea)" NARROW [] xref: GO:0030681 is_a: CCO:C0001038 ! ribonuclease P complex [Term] id: CCO:C0001043 name: preribosome namespace: cellular_component def: "Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis." [PMID:10567516] subset: goslim_pir xref: GO:0030684 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001044 name: nucleolar preribosome namespace: cellular_component def: "Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis." [PMID:10567516] xref: GO:0030685 is_a: CCO:C0001043 ! preribosome is_a: CCO:C0001871 ! nucleolar part [Term] id: CCO:C0001045 name: 90S preribosome namespace: cellular_component def: "A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins." [PMID:12150911, PMID:12957375, PMID:15120992] xref: GO:0030686 is_a: CCO:C0001044 ! nucleolar preribosome [Term] id: CCO:C0001046 name: nucleolar preribosome, large subunit precursor namespace: cellular_component def: "A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit." [PMID:10567516] comment: Note that this complex is 66S in Saccharomyces. synonym: "66S preribosome" NARROW [] xref: GO:0030687 is_a: CCO:C0001044 ! nucleolar preribosome [Term] id: CCO:C0001047 name: nucleolar preribosome, small subunit precursor namespace: cellular_component def: "A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit." [PMID:10567516] comment: Note that this complex is 43S in Saccharomyces. synonym: "43S preribosome" NARROW [] xref: GO:0030688 is_a: CCO:C0001044 ! nucleolar preribosome [Term] id: CCO:C0001048 name: Noc complex namespace: cellular_component def: "Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis." [PMID:12446671] comment: Note that the definition uses Saccharomyces gene product names because this complex has only been described in Saccharomyces cerevisiae and no other names have yet arisen; the term nevertheless can be used for analogous complexes in other eukaryotes, and the definition can be changed if better wording is found. subset: goslim_pir xref: GO:0030689 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001049 name: Noc1p-Noc2p complex namespace: cellular_component def: "A heterodimer associated with 90S and 66S preribosomes in the nucleolus; involved in ribosomal large subunit biogenesis." [PMID:12446671] comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. xref: GO:0030690 is_a: CCO:C0001048 ! Noc complex is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001871 ! nucleolar part relationship: part_of CCO:C0001045 ! 90S preribosome relationship: part_of CCO:C0001046 ! nucleolar preribosome, large subunit precursor [Term] id: CCO:C0001050 name: Noc2p-Noc3p complex namespace: cellular_component def: "A heterodimer associated with 66S preribosomes; also found throughout the nucleoplasm; involved in ribosomal large subunit biogenesis." [PMID:12446671] comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. xref: GO:0030691 is_a: CCO:C0001048 ! Noc complex is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001870 ! nucleoplasm part is_a: CCO:C0001871 ! nucleolar part relationship: part_of CCO:C0001046 ! nucleolar preribosome, large subunit precursor [Term] id: CCO:C0001051 name: Noc4p-Nop14p complex namespace: cellular_component def: "A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis." [PMID:12446671] comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. xref: GO:0030692 is_a: CCO:C0001048 ! Noc complex is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001871 ! nucleolar part relationship: part_of CCO:C0001045 ! 90S preribosome relationship: part_of CCO:C0001047 ! nucleolar preribosome, small subunit precursor [Term] id: CCO:C0001053 name: glycine reductase complex namespace: cellular_component def: "Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C." [GOC:mah, PMID:2018775] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glycine reductase activity ; GO:0030699'. subset: gosubset_prok xref: GO:0030700 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001054 name: autosome namespace: cellular_component def: "Any chromosome other than a sex chromosome." [GOC:mah] comment: Note that this term is mainly relevant in organisms that have both sex chromosomes and non-sex-determining chromosomes in an individual organism. xref: GO:0030849 is_a: CCO:C0000296 ! chromosome [Term] id: CCO:C0001055 name: cortical cytoskeleton namespace: cellular_component def: "The portion of the cytoskeleton that lies just beneath the plasma membrane." [GOC:mah] xref: GO:0030863 is_a: CCO:C0000421 ! cytoskeleton is_a: CCO:C0001867 ! cell cortex part relationship: location_of CCO:B0001397 ! ACTN4_HUMAN relationship: location_of CCO:B0034706 ! DLG4_HUMAN-Phosphotyrosine432 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035817 ! TRPC4_HUMAN-Phosphoserine195 [Term] id: CCO:C0001056 name: cortical actin cytoskeleton namespace: cellular_component def: "The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane." [GOC:mah] xref: GO:0030864 is_a: CCO:C0001055 ! cortical cytoskeleton is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0033316 ! DEST_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0067575 ! LASP1_HUMAN-Phosphoserine146 relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0001057 name: rough endoplasmic reticulum membrane namespace: cellular_component def: "The lipid bilayer surrounding the rough endoplasmic reticulum." [GOC:mah] synonym: "rough ER membrane" EXACT [] xref: GO:0030867 is_a: CCO:C0000370 ! endoplasmic reticulum membrane relationship: location_of CCO:B0040688 ! RPN1_HUMAN relationship: location_of CCO:B0062790 ! PLOD3_HUMAN relationship: location_of CCO:B0063104 ! PLOD1_HUMAN relationship: location_of CCO:B0069305 ! PI4KB_HUMAN-Phosphoserine511 relationship: part_of CCO:C0000372 ! rough endoplasmic reticulum [Term] id: CCO:C0001058 name: smooth endoplasmic reticulum membrane namespace: cellular_component def: "The lipid bilayer surrounding the smooth endoplasmic reticulum." [GOC:mah] synonym: "smooth ER membrane" EXACT [] xref: GO:0030868 is_a: CCO:C0000370 ! endoplasmic reticulum membrane relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: part_of CCO:C0000371 ! smooth endoplasmic reticulum [Term] id: CCO:C0001059 name: RENT complex namespace: cellular_component def: "A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit." [PMID:12196389] xref: GO:0030869 is_a: CCO:C0000280 ! chromatin silencing complex [Term] id: CCO:C0001060 name: Mre11 complex namespace: cellular_component def: "Trimeric protein complex that possesses endonuclease activity; involved in DNA repair and checkpoint signaling. In Saccharomyces the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins related to the Saccharomyces proteins." [GOC:mah, PMID:11988766] synonym: "MRN complex" EXACT [] synonym: "MRX complex" EXACT [] synonym: "Rad50 complex" EXACT [] synonym: "Rad50-Rad32-Nbs1 complex" EXACT [] synonym: "RMX complex" EXACT [] xref: GO:0030870 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0002021 ! RAD50_HUMAN relationship: location_of CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 [Term] id: CCO:C0001064 name: nucleolar chromatin namespace: cellular_component def: "The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA." [GOC:mah] xref: GO:0030874 is_a: CCO:C0001871 ! nucleolar part is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000117 ! nuclear chromatin [Term] id: CCO:C0001065 name: rDNA protrusion namespace: cellular_component def: "Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining." [PMID:1629244] comment: Note that this component is characterized in Schizosaccharomyces, particularly with respect to the DAPI staining pattern. synonym: "ribosomal DNA protrusion" EXACT [] xref: GO:0030875 is_a: CCO:C0001871 ! nucleolar part is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0001064 ! nucleolar chromatin [Term] id: CCO:C0001066 name: interleukin-20 receptor complex namespace: cellular_component def: "Complex that binds interleukin-20; comprises an alpha and a beta subunit." [GOC:mah] xref: GO:0030876 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001067 name: beta-catenin destruction complex namespace: cellular_component def: "A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome." [PMID:14600025] synonym: "beta-catenin degradation complex" EXACT [] xref: GO:0030877 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0001367 ! AXN1_HUMAN relationship: location_of CCO:B0010567 ! APC_HUMAN-Phosphoserine1038 relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0034845 ! GSK3B_HUMAN-Phosphoserine215 [Term] id: CCO:C0001068 name: RNA polymerase complex namespace: cellular_component def: "Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits." [GOC:mah] subset: goslim_pir subset: gosubset_prok synonym: "multisubunit RNA polymerase" EXACT [] xref: GO:0030880 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0054167 ! B0QYL8_HUMAN relationship: location_of CCO:B0054168 ! B0QYL9_HUMAN relationship: location_of CCO:B0070150 ! RPAB2_HUMAN-Phosphoserine2 [Term] id: CCO:C0001069 name: VCB complex namespace: cellular_component def: "A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1." [GOC:mah, PMID:11865071] synonym: "pVHL-elongin C-elongin B complex" EXACT [] synonym: "VHL complex" EXACT [] synonym: "von Hippel-Lindau tumor suppressor complex" EXACT [] xref: GO:0030891 is_a: CCO:C0000028 ! cytoplasmic ubiquitin ligase complex relationship: location_of CCO:B0058484 ! NEUL2_HUMAN relationship: location_of CCO:B0063468 ! UBP33_HUMAN [Term] id: CCO:C0001070 name: mitotic cohesin complex namespace: cellular_component def: "A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex." [GOC:mah, PMID:12750522] xref: GO:0030892 is_a: CCO:C0000538 ! cohesin complex relationship: location_of CCO:B0001847 ! SGOL1_HUMAN relationship: location_of CCO:B0014044 ! SGOL2_HUMAN-Phosphothreonine845 [Term] id: CCO:C0001071 name: meiotic cohesin complex namespace: cellular_component def: "A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex." [GOC:mah, PMID:12750522] xref: GO:0030893 is_a: CCO:C0000538 ! cohesin complex [Term] id: CCO:C0001072 name: replisome namespace: cellular_component def: "A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins." [GOC:mah, GOC:vw] subset: goslim_pir subset: gosubset_prok xref: GO:0030894 is_a: CCO:C0001494 ! protein-DNA complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000265 ! replication fork [Term] id: CCO:C0001073 name: apolipoprotein B mRNA editing enzyme complex namespace: cellular_component def: "Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP)." [PMID:10781591] synonym: "apoB mRNA editing enzyme complex" EXACT [] synonym: "APOBEC" EXACT [] xref: GO:0030895 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0006255 ! ABC3G_HUMAN relationship: location_of CCO:B0058866 ! A1CF_HUMAN [Term] id: CCO:C0001074 name: checkpoint clamp complex namespace: cellular_component def: "Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage." [PMID:12531008] comment: Note that the following subunit names have been used: human RAD9/RAD1/HUS1; S. pombe Rad9/Rad1/Hus1; S. cerevisiae Ddc1p/Rad17p/Mec3p. synonym: "CCC" EXACT [] synonym: "Rad9-Hus1-Rad1 (9-1-1) clamp complex" EXACT [] xref: GO:0030896 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0001075 name: HOPS complex namespace: cellular_component def: "A multimeric protein complex that associates with the vacuolar membrane and is involved in homotypic vacuole fusion and vacuole protein sorting. For example, the Saccharomyces complex contains Vps41p, Vam6p, Pep5p, Vps16p, Pep3p, and Vps33p." [PMID:10944212] xref: GO:0030897 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001856 ! vacuolar part relationship: part_of CCO:C0000356 ! vacuolar membrane [Term] id: CCO:C0001076 name: retromer complex namespace: cellular_component def: "A conserved multimeric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. For example, the budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p." [PMID:9700157] subset: goslim_pir xref: GO:0030904 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0000733 ! endomembrane system [Term] id: CCO:C0001077 name: retromer complex, outer shell namespace: cellular_component def: "One of two subcomplexes that combine to form the retromer, believed to be peripherally associated with the membrane. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer." [PMID:9700157] xref: GO:0030905 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0001076 ! retromer complex [Term] id: CCO:C0001078 name: retromer complex, inner shell namespace: cellular_component def: "One of two subcomplexes that combine to form the retromer, believed to be closely associated with the membrane. In budding yeast the complex comprises Vps35p, Vps29p, and Vps26p." [PMID:9700157] xref: GO:0030906 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0001076 ! retromer complex [Term] id: CCO:C0001079 name: MBF transcription complex namespace: cellular_component def: "A complex of two or three proteins that binds to the Mlu1 cell cycle box (MCB) promoter element and is involved in cell cycle-dependent regulation of transcription. In Saccharomyces the complex consists of Mbp1p and Swi6p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p." [PMID:9343385] synonym: "DSC1 transcription factor complex" EXACT [] synonym: "MBF" EXACT [] synonym: "Mlu1-box binding factor" EXACT [] xref: GO:0030907 is_a: CCO:C0000272 ! transcription factor complex [Term] id: CCO:C0001080 name: STAGA complex namespace: cellular_component def: "A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The composition is similar to that of the SAGA complex; for example, the human complex contains the transcription-transformation cofactor TRRAP, hGCN5L acetylase, novel human ADA-like and SPT-like cofactors, and a subset of TAFs." [PMID:11564863] comment: See also the cellular component term 'SAGA complex ; GO:0000124'. xref: GO:0030914 is_a: CCO:C0000011 ! histone acetyltransferase complex [Term] id: CCO:C0001081 name: Smc5-Smc6 complex namespace: cellular_component def: "A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S.cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans." [GOC:rb, PMID:14701739] xref: GO:0030915 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000120 ! condensed chromosome [Term] id: CCO:C0001082 name: ADPG pyrophosphorylase complex namespace: cellular_component def: "Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits." [GOC:tb, PMID:9680965] subset: goslim_pir subset: gosubset_prok xref: GO:0030929 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001083 name: homotetrameric ADPG pyrophosphorylase complex namespace: cellular_component def: "A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the Bacteria (Bacteria, ncbi_taxonomy_id:2)." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "ADPG pyrophosphorylase complex (sensu Bacteria)" EXACT [] xref: GO:0030930 is_a: CCO:C0001082 ! ADPG pyrophosphorylase complex [Term] id: CCO:C0001084 name: heterotetrameric ADPG pyrophosphorylase complex namespace: cellular_component def: "A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity; as in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759)." [GOC:mah, GOC:mtg_sensu] synonym: "ADPG pyrophosphorylase complex (sensu Eukaryota)" EXACT [] xref: GO:0030931 is_a: CCO:C0001082 ! ADPG pyrophosphorylase complex [Term] id: CCO:C0001085 name: amyloplast ADPG pyrophosphorylase complex namespace: cellular_component def: "An ADPG pyrophosphorylase complex found in the amyloplast." [GOC:mah] xref: GO:0030932 is_a: CCO:C0001106 ! plastid ADPG pyrophosphorylase complex relationship: part_of CCO:C0000630 ! amyloplast [Term] id: CCO:C0001086 name: chloroplast ADPG pyrophosphorylase complex namespace: cellular_component def: "An ADPG pyrophosphorylase complex found in the chloroplast." [GOC:mah] xref: GO:0030933 is_a: CCO:C0001106 ! plastid ADPG pyrophosphorylase complex is_a: CCO:C0001853 ! chloroplast part [Term] id: CCO:C0001087 name: anchoring collagen namespace: cellular_component def: "Any collagen polymer which links one collagen assembly, such as a collagen fibril or sheet, to other structures." [ISBN:0721639976] synonym: "connecting collagen" EXACT [ISBN:0721639976] synonym: "linking collagen" EXACT [ISBN:0721639976] xref: GO:0030934 is_a: CCO:C0000205 ! collagen [Term] id: CCO:C0001088 name: sheet-forming collagen namespace: cellular_component def: "Any collagen polymer in which collagen triple helices associate to form sheet-like networks." [ISBN:0721639976] synonym: "network-forming collagen" EXACT [ISBN:0815316194] xref: GO:0030935 is_a: CCO:C0000205 ! collagen [Term] id: CCO:C0001089 name: transmembrane collagen namespace: cellular_component def: "Any collagen polymer that passes through a lipid bilayer membrane." [ISBN:0721639976] synonym: "MACIT" EXACT [ISBN:0198599587] xref: GO:0030936 is_a: CCO:C0000205 ! collagen [Term] id: CCO:C0001090 name: collagen type XVII namespace: cellular_component def: "A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices associate with hemidesmosomes and the basal lamina." [ISBN:0721639976] xref: GO:0030937 is_a: CCO:C0001089 ! transmembrane collagen [Term] id: CCO:C0001091 name: collagen type XVIII namespace: cellular_component def: "A collagen homotrimer of alpha1(XVIII) chains." [ISBN:0721639976] xref: GO:0030938 is_a: CCO:C0001087 ! anchoring collagen [Term] id: CCO:C0001092 name: glutamyl-tRNA(Gln) amidotransferase complex namespace: cellular_component def: "Complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms." [GOC:mlg] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glutamyl-tRNA(Gln) amidotransferase activity ; GO:0017068'. xref: GO:0030956 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001093 name: RITS complex namespace: cellular_component def: "A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing." [PMID:14704433] xref: GO:0030958 is_a: CCO:C0001205 ! RNAi effector complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000310 ! nuclear heterochromatin [Term] id: CCO:C0001096 name: cortical microtubule cytoskeleton namespace: cellular_component def: "The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane." [GOC:mah] xref: GO:0030981 is_a: CCO:C0001055 ! cortical cytoskeleton relationship: location_of CCO:B0012763 ! MARE1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: part_of CCO:C0000754 ! microtubule cytoskeleton [Term] id: CCO:C0001097 name: high molecular weight kininogen receptor complex namespace: cellular_component def: "A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins." [GOC:mah, PMID:11290596] xref: GO:0030988 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001098 name: intraflagellar transport particle namespace: cellular_component def: "A nonmembrane-bound oliogmeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." [GOC:kva, PMID:14570576] subset: goslim_pir xref: GO:0030990 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part [Term] id: CCO:C0001099 name: intraflagellar transport particle A namespace: cellular_component def: "The smaller subcomplex of the intraflagellar transport particle; characterized complexes have molecular weights of 710-760 kDa." [GOC:kva, PMID:14570576] xref: GO:0030991 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part relationship: part_of CCO:C0001098 ! intraflagellar transport particle [Term] id: CCO:C0001100 name: intraflagellar transport particle B namespace: cellular_component def: "The larger subcomplex of the intraflagellar transport particle; characterized complexes have molecular weights around 550 kDa." [GOC:kva, PMID:14570576] xref: GO:0030992 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part relationship: part_of CCO:C0001098 ! intraflagellar transport particle [Term] id: CCO:C0001101 name: axonemal heterotrimeric kinesin-II complex namespace: cellular_component def: "A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme." [GOC:kva, PMID:14570576] xref: GO:0030993 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001866 ! axoneme part [Term] id: CCO:C0001102 name: linear element namespace: cellular_component def: "A proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase. Linear elements have a structure related to but not equivalent to the synaptonemal complex." [Sanger:jb "Jurg Bahler"] xref: GO:0030998 is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0001103 name: actin rod namespace: cellular_component def: "A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Found in the germinating spores of Dictyostelium discoideum." [GOC:kp] xref: GO:0031002 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0001104 name: actin tubule namespace: cellular_component def: "A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together." [GOC:kp] xref: GO:0031003 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0001103 ! actin rod [Term] id: CCO:C0001105 name: potassium ion-transporting ATPase complex namespace: cellular_component def: "Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex." [PMID:10608856, PMID:9858692, TIGR_TIGRFAMS:TIGR01497] synonym: "Kdp system complex" EXACT [] xref: GO:0031004 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001106 name: plastid ADPG pyrophosphorylase complex namespace: cellular_component def: "An ADPG pyrophosphorylase complex found in a plastid." [GOC:mah] xref: GO:0031009 is_a: CCO:C0001084 ! heterotetrameric ADPG pyrophosphorylase complex is_a: CCO:C0001854 ! plastid part [Term] id: CCO:C0001107 name: ISWI complex namespace: cellular_component def: "Any chromatin remodeling complex that contains an ATPase subunit of the ISWI family." [GOC:mah, PMID:15020051] xref: GO:0031010 is_a: CCO:C0000806 ! chromatin remodeling complex [Term] id: CCO:C0001108 name: INO80 complex namespace: cellular_component def: "A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity." [GOC:jh] xref: GO:0031011 is_a: CCO:C0000806 ! chromatin remodeling complex is_a: CCO:C0001555 ! DNA helicase complex [Term] id: CCO:C0001109 name: extracellular matrix namespace: cellular_component def: "A structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as in plants)." [GOC:mah] subset: goslim_pir subset: gosubset_prok xref: GO:0031012 is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0005964 ! PGBM_HUMAN relationship: location_of CCO:B0019657 ! ATL4_HUMAN relationship: location_of CCO:B0019689 ! ATS1_HUMAN relationship: location_of CCO:B0019703 ! Q59FE5_HUMAN relationship: location_of CCO:B0023795 ! PCSK6_HUMAN relationship: location_of CCO:B0031878 ! VWF_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0034581 ! ATS8_HUMAN-Phosphotyrosine255 relationship: location_of CCO:B0053811 ! A6NF00_HUMAN relationship: location_of CCO:B0053833 ! A6NGS5_HUMAN relationship: location_of CCO:B0054195 ! B0YJ32_HUMAN relationship: location_of CCO:B0054418 ! LAMA5_HUMAN relationship: location_of CCO:B0054985 ! LAMC1_HUMAN relationship: location_of CCO:B0055184 ! LAMA1_HUMAN relationship: location_of CCO:B0055322 ! COIA1_HUMAN relationship: location_of CCO:B0056656 ! Q5VUM2_HUMAN relationship: location_of CCO:B0056963 ! Q6VU67_HUMAN relationship: location_of CCO:B0056964 ! Q6VU68_HUMAN relationship: location_of CCO:B0064443 ! CO3A1_HUMAN-Phosphoserine1383 [Term] id: CCO:C0001110 name: karyopherin docking complex namespace: cellular_component def: "A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p." [PMID:11867631, PMID:9864357] synonym: "Asm4p-containing complex" NARROW [] synonym: "nuclear pore subcomplex" BROAD [] xref: GO:0031015 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001872 ! nuclear membrane part relationship: part_of CCO:C0000260 ! nuclear pore [Term] id: CCO:C0001111 name: mitochondrial mRNA editing complex namespace: cellular_component def: "An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates." [GOC:mah, PMID:12139607] synonym: "mitochondrial editosome" EXACT [] xref: GO:0031019 is_a: CCO:C0001945 ! mRNA editing complex [Term] id: CCO:C0001112 name: plastid mRNA editing complex namespace: cellular_component def: "An mRNA editing complex found in a plastid." [GOC:mah] synonym: "plastid editosome" EXACT [] xref: GO:0031020 is_a: CCO:C0001945 ! mRNA editing complex [Term] id: CCO:C0001113 name: interphase microtubule organizing center namespace: cellular_component def: "A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus." [PMID:15068790] synonym: "iMTOC" EXACT [] synonym: "interphase microtubule organising center" EXACT [] synonym: "interphase MTOC" EXACT [] xref: GO:0031021 is_a: CCO:C0000385 ! microtubule organizing center relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 [Term] id: CCO:C0001114 name: glutamate synthase complex namespace: cellular_component def: "A complex that possesses glutamate synthase activity." [GOC:mah] subset: goslim_pir subset: gosubset_prok xref: GO:0031026 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001115 name: glutamate synthase complex (NADH) namespace: cellular_component def: "A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity." [GOC:jl, PMID:7047525] xref: GO:0031027 is_a: CCO:C0001114 ! glutamate synthase complex [Term] id: CCO:C0001116 name: macronucleus namespace: cellular_component def: "A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell." [GOC:ns] xref: GO:0031039 is_a: CCO:C0000252 ! nucleus [Term] id: CCO:C0001117 name: micronucleus namespace: cellular_component def: "A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell." [GOC:ns] xref: GO:0031040 is_a: CCO:C0000252 ! nucleus [Term] id: CCO:C0001118 name: dense core granule namespace: cellular_component def: "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted." [PMID:14690495] xref: GO:0031045 is_a: CCO:C0000985 ! secretory granule [Term] id: CCO:C0001119 name: nucleocytoplasmic shuttling complex namespace: cellular_component def: "Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores." [GOC:mah] subset: goslim_pir xref: GO:0031074 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0021718 ! NUP62_HUMAN [Term] id: CCO:C0001120 name: Nup107-160 complex namespace: cellular_component def: "A subcomplex of the nuclear pore complex (NPC) mRNA export and NPC assembly. Contains conserved nucleoporins and other proteins; for example, the Saccharomyces complex contains Nup84p, Nup85p, Nup120p, Nup145p-C, Seh1p, Sec13p, and Nup133p." [PMID:10747086, PMID:11823431, PMID:15226438] synonym: "Nup107-120 complex" EXACT [] synonym: "Nup84 complex" EXACT [] xref: GO:0031080 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001872 ! nuclear membrane part relationship: part_of CCO:C0000260 ! nuclear pore [Term] id: CCO:C0001121 name: BLOC complex namespace: cellular_component def: "Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex." [PMID:15102850, PMID:15261680] subset: goslim_pir xref: GO:0031082 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0001122 name: BLOC-1 complex namespace: cellular_component def: "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins." [PMID:15102850] xref: GO:0031083 is_a: CCO:C0001121 ! BLOC complex [Term] id: CCO:C0001123 name: BLOC-2 complex namespace: cellular_component def: "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru." [PMID:12548288, PMID:14718540, PMID:15031569] xref: GO:0031084 is_a: CCO:C0001121 ! BLOC complex [Term] id: CCO:C0001124 name: BLOC-3 complex namespace: cellular_component def: "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins." [PMID:12756248] xref: GO:0031085 is_a: CCO:C0001121 ! BLOC complex [Term] id: CCO:C0001125 name: platelet dense granule membrane namespace: cellular_component def: "The lipid bilayer surrounding the platelet dense granule." [GOC:mah] xref: GO:0031088 is_a: CCO:C0001031 ! secretory granule membrane relationship: part_of CCO:C0001705 ! platelet dense granule [Term] id: CCO:C0001126 name: platelet dense granule lumen namespace: cellular_component def: "The volume enclosed by the membrane of the platelet dense granule." [GOC:mah] xref: GO:0031089 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: location_of CCO:B0001469 ! PDGFB_HUMAN relationship: location_of CCO:B0001480 ! PDGFA_HUMAN relationship: part_of CCO:C0001705 ! platelet dense granule [Term] id: CCO:C0001127 name: organelle membrane namespace: cellular_component def: "The lipid bilayer surrounding an organelle." [GOC:mah] subset: gosubset_prok xref: GO:0031090 is_a: CCO:C0000766 ! membrane is_a: CCO:C0001841 ! organelle part relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: part_of CCO:C0002127 ! membrane-bounded organelle [Term] id: CCO:C0001128 name: platelet alpha granule namespace: cellular_component def: "A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG)." [PMID:8467233] synonym: "platelet alpha-granule" EXACT [] xref: GO:0031091 is_a: CCO:C0000985 ! secretory granule relationship: location_of CCO:B0031878 ! VWF_HUMAN [Term] id: CCO:C0001129 name: platelet alpha granule membrane namespace: cellular_component def: "The lipid bilayer surrounding the platelet alpha granule." [GOC:mah, PMID:8467233] synonym: "platelet alpha-granule membrane" EXACT [] xref: GO:0031092 is_a: CCO:C0001031 ! secretory granule membrane relationship: location_of CCO:B0026215 ! ITA2B_HUMAN relationship: location_of CCO:B0033141 ! ITB3_HUMAN relationship: location_of CCO:B0035358 ! PECA1_HUMAN-Phosphotyrosine713 relationship: location_of CCO:B0066536 ! GP1BB_HUMAN-Phosphothreonine193 relationship: part_of CCO:C0001128 ! platelet alpha granule [Term] id: CCO:C0001130 name: platelet alpha granule lumen namespace: cellular_component def: "The volume enclosed by the membrane of the platelet alpha granule." [GOC:mah, PMID:8467233] synonym: "platelet alpha-granule lumen" EXACT [] xref: GO:0031093 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: location_of CCO:B0001402 ! VEGFD_HUMAN relationship: location_of CCO:B0001470 ! EGF_HUMAN relationship: location_of CCO:B0001471 ! TGFB1_HUMAN relationship: location_of CCO:B0001507 ! TGFB3_HUMAN relationship: location_of CCO:B0001634 ! VEGFB_HUMAN relationship: location_of CCO:B0001635 ! VEGFC_HUMAN relationship: location_of CCO:B0001687 ! TGFB2_HUMAN relationship: location_of CCO:B0010385 ! A4_HUMAN-Phosphoserine730 relationship: location_of CCO:B0012184 ! HGF_HUMAN-Pyrrolidone carboxylic acid32 relationship: location_of CCO:B0014612 ! VEGFA_HUMAN-N6-acetyllysine152 relationship: location_of CCO:B0028166 ! A1AT_HUMAN relationship: location_of CCO:B0031949 ! FINC_HUMAN relationship: location_of CCO:B0035955 ! CXCL7_HUMAN relationship: location_of CCO:B0041664 ! PLF4_HUMAN relationship: location_of CCO:B0043821 ! IGF1B_HUMAN relationship: location_of CCO:B0054308 ! LFTY2_HUMAN relationship: location_of CCO:B0054853 ! IGF1A_HUMAN relationship: location_of CCO:B0054866 ! FIBB_HUMAN relationship: location_of CCO:B0054867 ! FIBG_HUMAN relationship: location_of CCO:B0054874 ! ALBU_HUMAN relationship: location_of CCO:B0054944 ! SPRC_HUMAN relationship: location_of CCO:B0066189 ! FIBA_HUMAN-Phosphoserine364 relationship: part_of CCO:C0001128 ! platelet alpha granule [Term] id: CCO:C0001131 name: platelet dense tubular network namespace: cellular_component def: "A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin." [PMID:1322202] subset: goslim_pir xref: GO:0031094 is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0001557 ! PAR1_HUMAN [Term] id: CCO:C0001132 name: platelet dense tubular network membrane namespace: cellular_component def: "The lipid bilayer surrounding the platelet dense tubular network." [GOC:mah, PMID:1322202] xref: GO:0031095 is_a: CCO:C0001127 ! organelle membrane relationship: location_of CCO:B0067166 ! ITPR1_HUMAN-Phosphoserine1598 relationship: part_of CCO:C0001131 ! platelet dense tubular network [Term] id: CCO:C0001133 name: platelet dense tubular network lumen namespace: cellular_component def: "The volume enclosed by the membranes of the platelet dense tubular network." [GOC:mah, PMID:1322202] xref: GO:0031096 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0001131 ! platelet dense tubular network [Term] id: CCO:C0001134 name: medial ring namespace: cellular_component def: "A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning." [GOC:vw, PMID:15572668] synonym: "medial cortex" RELATED [] xref: GO:0031097 is_a: CCO:C0001404 ! cell division site part is_a: CCO:C0001867 ! cell cortex part [Term] id: CCO:C0001135 name: septin complex namespace: cellular_component def: "Any of several heterooligomeric complexes containing multiple septins." [GOC:mah, PMID:15385632] subset: goslim_pir xref: GO:0031105 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001867 ! cell cortex part relationship: location_of CCO:B0001319 ! A6NC65_HUMAN relationship: location_of CCO:B0001324 ! A6NFQ9_HUMAN relationship: location_of CCO:B0001335 ! A6NKP6_HUMAN relationship: location_of CCO:B0001339 ! A6NMH6_HUMAN relationship: location_of CCO:B0001846 ! Q59GE1_HUMAN relationship: location_of CCO:B0001925 ! SEP14_HUMAN relationship: location_of CCO:B0002011 ! SEPT1_HUMAN relationship: location_of CCO:B0002050 ! Q96MY5_HUMAN relationship: location_of CCO:B0002079 ! Q99648_HUMAN relationship: location_of CCO:B0002085 ! SEPT5_HUMAN relationship: location_of CCO:B0002198 ! SEPT3_HUMAN relationship: location_of CCO:B0013990 ! SEP11_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013991 ! SEPT2_HUMAN-Phosphotyrosine17 relationship: location_of CCO:B0014000 ! SEPT6_HUMAN-Phosphoserine411 relationship: location_of CCO:B0014006 ! SEPT7_HUMAN-Phosphoserine423 relationship: location_of CCO:B0014009 ! SEPT8_HUMAN-Phosphoserine10 relationship: location_of CCO:B0023340 ! Q59H84_HUMAN relationship: location_of CCO:B0023347 ! Q9H9P7_HUMAN relationship: location_of CCO:B0023351 ! Q6B514_HUMAN relationship: location_of CCO:B0023650 ! Q53QU3_HUMAN relationship: location_of CCO:B0026253 ! SEP12_HUMAN relationship: location_of CCO:B0028285 ! SEP13_HUMAN relationship: location_of CCO:B0030400 ! A8K7M3_HUMAN relationship: location_of CCO:B0033797 ! Q548C9_HUMAN relationship: location_of CCO:B0033798 ! Q541S4_HUMAN relationship: location_of CCO:B0041227 ! B1AHR1_HUMAN relationship: location_of CCO:B0041234 ! B1AMS2_HUMAN relationship: location_of CCO:B0070371 ! SEP10_HUMAN-Phosphoserine451 relationship: part_of CCO:C0001405 ! septin cytoskeleton [Term] id: CCO:C0001136 name: pseudopodium namespace: cellular_component def: "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir synonym: "pseudopod" EXACT [] xref: GO:0031143 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0001397 ! ACTN4_HUMAN relationship: location_of CCO:B0005642 ! ACTN2_HUMAN relationship: location_of CCO:B0005948 ! ACTN1_HUMAN relationship: location_of CCO:B0020080 ! ACTN3_HUMAN [Term] id: CCO:C0001137 name: spore wall namespace: cellular_component def: "The specialized envelope lying outside the cell membrane of a spore." [GOC:mah, GOC:pg] synonym: "spore coat" EXACT [] xref: GO:0031160 is_a: CCO:C0000239 ! cell wall [Term] id: CCO:C0001138 name: contractile vacuolar membrane namespace: cellular_component def: "The lipid bilayer surrounding the contractile vacuole." [GOC:pg] xref: GO:0031164 is_a: CCO:C0000356 ! vacuolar membrane relationship: part_of CCO:C0000069 ! contractile vacuole [Term] id: CCO:C0001139 name: integral to contractile vacuolar membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the contractile vacuolar membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:pg] xref: GO:0031165 is_a: CCO:C0001140 ! integral to vacuolar membrane is_a: CCO:C0001198 ! intrinsic to contractile vacuolar membrane [Term] id: CCO:C0001140 name: integral to vacuolar membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the vacuolar membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031166 is_a: CCO:C0001188 ! integral to organelle membrane is_a: CCO:C0001197 ! intrinsic to vacuolar membrane [Term] id: CCO:C0001141 name: SNARE complex namespace: cellular_component def: "A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25." [PMID:10872468] xref: GO:0031201 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0006164 ! STX5_HUMAN relationship: location_of CCO:B0055862 ! SEC20_HUMAN relationship: location_of CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 [Term] id: CCO:C0001142 name: endoplasmic reticulum Sec complex namespace: cellular_component def: "An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex." [GOC:mtg_sensu, PMID:12158317, PMID:14617809] subset: goslim_pir synonym: "Sec complex (sensu Eukaryota)" EXACT [] xref: GO:0031205 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0001057 ! rough endoplasmic reticulum membrane [Term] id: CCO:C0001143 name: Sec complex-associated translocon complex namespace: cellular_component def: "A translocon complex physically associated with a Sec complex." [GOC:mah, PMID:12518317, PMID:14617809] xref: GO:0031206 is_a: CCO:C0000365 ! translocon complex relationship: part_of CCO:C0001142 ! endoplasmic reticulum Sec complex [Term] id: CCO:C0001144 name: Sec62/Sec63 complex namespace: cellular_component def: "A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p." [PMID:12518317, PMID:14617809] synonym: "ER protein translocation subcomplex " EXACT [] synonym: "Sec62/63 complex" EXACT [] xref: GO:0031207 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0001142 ! endoplasmic reticulum Sec complex [Term] id: CCO:C0001145 name: SCAR complex namespace: cellular_component def: "A heterotetrameric complex that includes orthologues of human PIR121, Nap125 and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction." [GOC:pg, PMID:12181570] synonym: "WAVE complex" EXACT [] xref: GO:0031209 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001146 name: palmitoyltransferase complex namespace: cellular_component def: "A dimeric complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue." [GOC:jh] xref: GO:0031211 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0001147 name: RSF complex namespace: cellular_component def: "A chromatin remodeling complex that mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In humans, the complex is composed of the ATPase hSNF2H and the HBXAP protein (RSF-1)." [PMID:12972596] synonym: "remodeling and spacing factor complex " EXACT [] xref: GO:0031213 is_a: CCO:C0000806 ! chromatin remodeling complex relationship: location_of CCO:B0070245 ! RSF1_HUMAN-Phosphoserine1349 relationship: location_of CCO:B0070643 ! SMCA5_HUMAN-Phosphoserine755 [Term] id: CCO:C0001148 name: intrinsic to membrane namespace: cellular_component def: "Located in a membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] comment: Note that proteins intrinsic to membranes cannot be removed without disrupting the membrane, e.g. by detergent. subset: gosubset_prok xref: GO:0031224 is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0005325 ! IL1R1_HUMAN relationship: location_of CCO:B0022069 ! Q5VZI8_HUMAN relationship: location_of CCO:B0022071 ! TLR4_HUMAN relationship: location_of CCO:B0030164 ! TLR1_HUMAN relationship: location_of CCO:B0030165 ! TLR10_HUMAN relationship: location_of CCO:B0030167 ! Q2NKL3_HUMAN relationship: location_of CCO:B0030171 ! TLR2_HUMAN relationship: location_of CCO:B0030172 ! TLR6_HUMAN relationship: location_of CCO:B0053698 ! A0AVG4_HUMAN relationship: location_of CCO:B0053764 ! A4FU63_HUMAN relationship: location_of CCO:B0054287 ! B1NLD0_HUMAN relationship: location_of CCO:B0054569 ! TLR5_HUMAN relationship: location_of CCO:B0054740 ! I18RA_HUMAN relationship: location_of CCO:B0055572 ! TIRAP_HUMAN relationship: location_of CCO:B0055691 ! ILRL1_HUMAN relationship: location_of CCO:B0055748 ! Q05B42_HUMAN relationship: location_of CCO:B0055913 ! IL18R_HUMAN relationship: location_of CCO:B0056212 ! Q2M3U3_HUMAN relationship: location_of CCO:B0056295 ! Q495P6_HUMAN relationship: location_of CCO:B0056756 ! SIGIR_HUMAN relationship: location_of CCO:B0056831 ! Q6JUT2_HUMAN relationship: location_of CCO:B0056942 ! SARM1_HUMAN relationship: location_of CCO:B0057293 ! TCAM2_HUMAN relationship: location_of CCO:B0058458 ! MYD88_HUMAN relationship: location_of CCO:B0058773 ! ILRL2_HUMAN relationship: location_of CCO:B0058832 ! IRPL2_HUMAN relationship: location_of CCO:B0058853 ! IL1AP_HUMAN relationship: location_of CCO:B0058891 ! TLR9_HUMAN relationship: location_of CCO:B0058892 ! TLR8_HUMAN relationship: location_of CCO:B0059005 ! IRPL1_HUMAN relationship: location_of CCO:B0066490 ! GNAS2_HUMAN-Phosphoserine51 relationship: location_of CCO:B0071419 ! TLR3_HUMAN-Phosphotyrosine858 relationship: location_of CCO:B0071420 ! TLR7_HUMAN-Phosphoserine1010 [Term] id: CCO:C0001149 name: anchored to membrane namespace: cellular_component def: "Tethered to a membrane by a covalently attached anchor, such as a lipid moiety, that is embedded in the membrane. When used to describe a protein, indicates that none of the peptide sequence is embedded in the membrane." [GOC:mah] xref: GO:0031225 is_a: CCO:C0001148 ! intrinsic to membrane relationship: location_of CCO:B0001455 ! RECK_HUMAN relationship: location_of CCO:B0001672 ! GAS1_HUMAN relationship: location_of CCO:B0002064 ! GML_HUMAN relationship: location_of CCO:B0005875 ! CD59_HUMAN relationship: location_of CCO:B0006244 ! TDGF1_HUMAN relationship: location_of CCO:B0006269 ! EFNA1_HUMAN relationship: location_of CCO:B0020491 ! N2DL3_HUMAN relationship: location_of CCO:B0026846 ! CNTFR_HUMAN relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0052321 ! CEAM6_HUMAN-Phosphoserine243 relationship: location_of CCO:B0054321 ! GFRA2_HUMAN relationship: location_of CCO:B0054570 ! GFRA3_HUMAN relationship: location_of CCO:B0054643 ! GPC4_HUMAN relationship: location_of CCO:B0054768 ! VNN1_HUMAN relationship: location_of CCO:B0054811 ! BY55_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054917 ! UROM_HUMAN relationship: location_of CCO:B0054928 ! CD14_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055177 ! CD24_HUMAN relationship: location_of CCO:B0055534 ! CAD13_HUMAN relationship: location_of CCO:B0055538 ! GFRA1_HUMAN relationship: location_of CCO:B0055723 ! UPAR_HUMAN relationship: location_of CCO:B0055836 ! BST2_HUMAN relationship: location_of CCO:B0055851 ! CNTN1_HUMAN relationship: location_of CCO:B0056149 ! LY6E_HUMAN relationship: location_of CCO:B0056863 ! RGMB_HUMAN relationship: location_of CCO:B0057365 ! CNTN4_HUMAN relationship: location_of CCO:B0058002 ! ITLN1_HUMAN relationship: location_of CCO:B0059276 ! CNTN6_HUMAN relationship: location_of CCO:B0062866 ! CD177_HUMAN relationship: location_of CCO:B0062941 ! NTNG2_HUMAN relationship: location_of CCO:B0063443 ! LIPL_HUMAN relationship: location_of CCO:B0063454 ! CD48_HUMAN relationship: location_of CCO:B0063491 ! SPRN_HUMAN relationship: location_of CCO:B0063507 ! LY6H_HUMAN [Term] id: CCO:C0001150 name: intrinsic to plasma membrane namespace: cellular_component def: "Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] subset: gosubset_prok xref: GO:0031226 is_a: CCO:C0001148 ! intrinsic to membrane is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0059236 ! RAB26_HUMAN relationship: location_of CCO:B0071528 ! TRAF7_HUMAN-Phosphoserine91 [Term] id: CCO:C0001151 name: intrinsic to endoplasmic reticulum membrane namespace: cellular_component def: "Located in the endoplasmic reticulum membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031227 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0001152 name: intrinsic to Golgi membrane namespace: cellular_component def: "Located in the Golgi membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031228 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001850 ! Golgi apparatus part relationship: part_of CCO:C0000021 ! Golgi membrane [Term] id: CCO:C0001153 name: intrinsic to nuclear inner membrane namespace: cellular_component def: "Located in the nuclear inner membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031229 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001872 ! nuclear membrane part relationship: part_of CCO:C0000254 ! nuclear inner membrane [Term] id: CCO:C0001154 name: intrinsic to cell outer membrane namespace: cellular_component def: "Located in the cell outer membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "intrinsic to outer membrane (sensu Gram-negative Bacteria)" EXACT [] synonym: "intrinsic to outer membrane (sensu Proteobacteria)" EXACT [] xref: GO:0031230 is_a: CCO:C0001148 ! intrinsic to membrane is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000557 ! cell outer membrane [Term] id: CCO:C0001155 name: intrinsic to peroxisomal membrane namespace: cellular_component def: "Located in the peroxisomal membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031231 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001858 ! peroxisomal part relationship: part_of CCO:C0000360 ! peroxisomal membrane [Term] id: CCO:C0001156 name: extrinsic to external side of plasma membrane namespace: cellular_component def: "Loosely bound to the surface of the plasma membrane that faces away from the cytoplasm, but not integrated into the hydrophobic region." [GOC:mah] xref: GO:0031232 is_a: CCO:C0000899 ! extrinsic to plasma membrane relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: part_of CCO:C0000702 ! external side of plasma membrane [Term] id: CCO:C0001157 name: intrinsic to external side of plasma membrane namespace: cellular_component def: "Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane, with the bulk of the gene product located on the side opposite to the side that faces the cytoplasm." [GOC:mah] xref: GO:0031233 is_a: CCO:C0001150 ! intrinsic to plasma membrane relationship: part_of CCO:C0000702 ! external side of plasma membrane [Term] id: CCO:C0001158 name: extrinsic to internal side of plasma membrane namespace: cellular_component def: "Loosely bound to the surface of the plasma membrane that faces the cytoplasm, but not integrated into the hydrophobic region." [GOC:mah] xref: GO:0031234 is_a: CCO:C0000899 ! extrinsic to plasma membrane is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0000703 ! internal side of plasma membrane [Term] id: CCO:C0001159 name: intrinsic to internal side of plasma membrane namespace: cellular_component def: "Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane, with the bulk of the gene product located on the side that faces the cytoplasm." [GOC:mah] xref: GO:0031235 is_a: CCO:C0001150 ! intrinsic to plasma membrane relationship: part_of CCO:C0000703 ! internal side of plasma membrane [Term] id: CCO:C0001160 name: extrinsic to external side of plasma membrane, in periplasmic space namespace: cellular_component def: "Located in the periplasmic space and loosely bound to the surface of the plasma membrane that faces away from the cytoplasm, but not integrated into the hydrophobic region." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "extrinsic to external side of plasma membrane, in periplasmic space (sensu Gram-negative Bacteria)" EXACT [] synonym: "extrinsic to external side of plasma membrane, in periplasmic space (sensu Proteobacteria)" EXACT [] xref: GO:0031236 xref: GO:0031238 is_a: CCO:C0001156 ! extrinsic to external side of plasma membrane is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000997 ! outer membrane-bounded periplasmic space [Term] id: CCO:C0001161 name: intrinsic to external side of plasma membrane, in periplasmic space namespace: cellular_component def: "Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane, with the bulk of the gene product located in the periplasmic space." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "intrinsic to external side of plasma membrane, in periplasmic space (sensu Gram-negative Bacteria)" EXACT [] synonym: "intrinsic to external side of plasma membrane, in periplasmic space (sensu Proteobacteria)" EXACT [] xref: GO:0031237 xref: GO:0031239 is_a: CCO:C0001157 ! intrinsic to external side of plasma membrane is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000997 ! outer membrane-bounded periplasmic space [Term] id: CCO:C0001162 name: external side of cell outer membrane namespace: cellular_component def: "The side of the outer membrane that is opposite to the side that faces the periplasm of the cell." [GOC:mlg, GOC:mtg_sensu] subset: gosubset_prok synonym: "external side of outer membrane" RELATED [] xref: GO:0031240 is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000557 ! cell outer membrane [Term] id: CCO:C0001163 name: internal side of cell outer membrane namespace: cellular_component def: "The side of the outer membrane that faces the periplasm of the cell." [GOC:mlg, GOC:mtg_sensu] subset: gosubset_prok synonym: "internal side of outer membrane" EXACT [] xref: GO:0031241 is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000557 ! cell outer membrane [Term] id: CCO:C0001164 name: extrinsic to external side of cell outer membrane namespace: cellular_component def: "Loosely bound to the surface of the outer membrane of the cell that faces away from the cytoplasm, but not integrated into the hydrophobic region." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "extrinsic to external side of outer membrane" EXACT [] xref: GO:0031242 is_a: CCO:C0001166 ! extrinsic to cell outer membrane relationship: part_of CCO:C0001162 ! external side of cell outer membrane [Term] id: CCO:C0001165 name: intrinsic to external side of cell outer membrane namespace: cellular_component def: "Located in the outer membrane of the cell such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane, with the bulk of the gene product located on the side opposite to the side that faces the periplasm." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "intrinsic to external side of outer membrane" EXACT [] xref: GO:0031243 is_a: CCO:C0001154 ! intrinsic to cell outer membrane relationship: part_of CCO:C0001162 ! external side of cell outer membrane [Term] id: CCO:C0001166 name: extrinsic to cell outer membrane namespace: cellular_component def: "Loosely bound to one surface of the outer membrane of the cell, but not integrated into the hydrophobic region." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "extrinsic to outer membrane (sensu Gram-negative Bacteria)" EXACT [] synonym: "extrinsic to outer membrane (sensu Proteobacteria)" EXACT [] xref: GO:0031244 is_a: CCO:C0000900 ! extrinsic to membrane is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000557 ! cell outer membrane [Term] id: CCO:C0001167 name: extrinsic to internal side of cell outer membrane namespace: cellular_component def: "Loosely bound to the surface of the outer membrane of the cell that faces the cytoplasm, but not integrated into the hydrophobic region." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "extrinsic to internal side of outer membrane" EXACT [] xref: GO:0031245 is_a: CCO:C0001166 ! extrinsic to cell outer membrane relationship: part_of CCO:C0001163 ! internal side of cell outer membrane [Term] id: CCO:C0001168 name: intrinsic to internal side of cell outer membrane namespace: cellular_component def: "Located in the outer membrane of the cell such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane, with the bulk of the gene product located on the side that faces the periplasm." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "intrinsic to internal side of outer membrane" EXACT [] xref: GO:0031246 is_a: CCO:C0001154 ! intrinsic to cell outer membrane relationship: part_of CCO:C0001163 ! internal side of cell outer membrane [Term] id: CCO:C0001169 name: protein acetyltransferase complex namespace: cellular_component def: "A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule." [GOC:bf] subset: goslim_pir xref: GO:0031248 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001170 name: anaerobic ribonucleoside-triphosphate reductase complex namespace: cellular_component def: "An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit." [GOC:mlg] xref: GO:0031250 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001171 name: PAN complex namespace: cellular_component def: "A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces." [PMID:9774670] synonym: "poly(A) nuclease complex" EXACT [] xref: GO:0031251 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001172 name: leading edge namespace: cellular_component def: "The area of a motile cell closest to the direction of movement." [GOC:pg] subset: goslim_pir synonym: "front of cell" EXACT [] xref: GO:0031252 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0056646 ! MRCKA_HUMAN relationship: location_of CCO:B0056729 ! MRCKG_HUMAN relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0064602 ! CXCR4_HUMAN-Phosphoserine319 relationship: location_of CCO:B0068275 ! MRCKB_HUMAN-Phosphoserine221 relationship: location_of CCO:B0070862 ! SRA1_HUMAN-Phosphothreonine68 [Term] id: CCO:C0001173 name: cell projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a cell surface projection." [GOC:mah] synonym: "membrane extension" RELATED [] synonym: "membrane projection" RELATED [] xref: GO:0031253 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001881 ! cell projection part relationship: location_of CCO:B0056054 ! RAB35_HUMAN [Term] id: CCO:C0001174 name: trailing edge namespace: cellular_component def: "The area of a motile cell opposite to the direction of movement." [GOC:pg] subset: goslim_pir synonym: "back of cell" EXACT [] xref: GO:0031254 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001175 name: lateral part of motile cell namespace: cellular_component def: "The area of a motile cell perpendicular to the direction of movement." [GOC:pg] xref: GO:0031255 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001176 name: leading edge membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the leading edge of a motile cell." [GOC:mah] xref: GO:0031256 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0001172 ! leading edge [Term] id: CCO:C0001177 name: trailing edge membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the trailing edge of a motile cell." [GOC:mah] xref: GO:0031257 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0001174 ! trailing edge [Term] id: CCO:C0001178 name: lamellipodium membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a lamellipodium." [GOC:mah] xref: GO:0031258 is_a: CCO:C0001173 ! cell projection membrane is_a: CCO:C0001176 ! leading edge membrane relationship: part_of CCO:C0000935 ! lamellipodium [Term] id: CCO:C0001179 name: uropod membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a uropod." [GOC:mah] synonym: "uropodium membrane" EXACT [] xref: GO:0031259 is_a: CCO:C0001173 ! cell projection membrane is_a: CCO:C0001177 ! trailing edge membrane relationship: part_of CCO:C0000189 ! uropod [Term] id: CCO:C0001180 name: pseudopodium membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a pseudopodium." [GOC:mah] xref: GO:0031260 is_a: CCO:C0001173 ! cell projection membrane relationship: part_of CCO:C0001136 ! pseudopodium [Term] id: CCO:C0001181 name: DNA replication preinitiation complex namespace: cellular_component def: "A multiprotein complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others." [PMID:12694535, PMID:15194812] synonym: "pre-IC" EXACT [] xref: GO:0031261 is_a: CCO:C0001494 ! protein-DNA complex is_a: CCO:C0001870 ! nucleoplasm part [Term] id: CCO:C0001182 name: Ndc80 complex namespace: cellular_component def: "A protein complex conserved among eukaryotes that forms part of the kinetochore and plays an essential role in forming stable kinetochore-microtubule attachments. The complex contains proteins known in several species, including budding and fission yeasts, as Ndc80p, Nuf2p, Spc24p, and Spc25p. In vertebrates it is part of the outer plate of the kinetochore." [PMID:15509863, PMID:15661517] synonym: "Nuf2-Ndc80 complex" EXACT [] xref: GO:0031262 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000103 ! kinetochore [Term] id: CCO:C0001183 name: death-inducing signaling complex namespace: cellular_component def: "A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor." [PMID:12628743, PMID:12655293] subset: goslim_pir synonym: "death-inducing signalling complex" EXACT [] synonym: "DISC" EXACT [] xref: GO:0031264 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001184 name: CD95 death-inducing signaling complex namespace: cellular_component def: "A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor." [PMID:12628743, PMID:12655293] synonym: "CD95 death-inducing signalling complex" EXACT [] synonym: "CD95 DISC" EXACT [] synonym: "Fas death-inducing signaling complex" EXACT [] xref: GO:0031265 is_a: CCO:C0001183 ! death-inducing signaling complex relationship: location_of CCO:B0066115 ! FAF1_HUMAN-Phosphothreonine580 [Term] id: CCO:C0001185 name: TRAIL death-inducing signaling complex namespace: cellular_component def: "A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor." [PMID:12628743, PMID:12655293] synonym: "TRAIL death-inducing signalling complex" EXACT [] synonym: "TRAIL DISC" EXACT [] xref: GO:0031266 is_a: CCO:C0001183 ! death-inducing signaling complex [Term] id: CCO:C0001186 name: replication fork protection complex namespace: cellular_component def: "A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling." [PMID:15367656] synonym: "Swi1-Swi3 complex" NARROW [] xref: GO:0031298 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0001793 ! nuclear replication fork [Term] id: CCO:C0001187 name: intrinsic to organelle membrane namespace: cellular_component def: "Located in an organelle membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031300 is_a: CCO:C0001148 ! intrinsic to membrane is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0001127 ! organelle membrane [Term] id: CCO:C0001188 name: integral to organelle membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of an organelle membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031301 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001187 ! intrinsic to organelle membrane [Term] id: CCO:C0001189 name: intrinsic to endosome membrane namespace: cellular_component def: "Located in the endosome membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031302 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001859 ! endosomal part relationship: part_of CCO:C0000713 ! endosome membrane [Term] id: CCO:C0001190 name: integral to endosome membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the endosome membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031303 is_a: CCO:C0001188 ! integral to organelle membrane is_a: CCO:C0001189 ! intrinsic to endosome membrane [Term] id: CCO:C0001191 name: intrinsic to mitochondrial inner membrane namespace: cellular_component def: "Located in the mitochondrial inner membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031304 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0001192 name: integral to mitochondrial inner membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the mitochondrial inner membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031305 is_a: CCO:C0001191 ! intrinsic to mitochondrial inner membrane is_a: CCO:C0001472 ! integral to mitochondrial membrane [Term] id: CCO:C0001193 name: intrinsic to mitochondrial outer membrane namespace: cellular_component def: "Located in the mitochondrial outer membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031306 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001874 ! mitochondrial membrane part relationship: location_of CCO:B0050997 ! MFN2_HUMAN relationship: part_of CCO:C0000327 ! mitochondrial outer membrane [Term] id: CCO:C0001194 name: integral to mitochondrial outer membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the mitochondrial outer membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031307 is_a: CCO:C0001193 ! intrinsic to mitochondrial outer membrane is_a: CCO:C0001472 ! integral to mitochondrial membrane relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0057377 ! MIRO2_HUMAN relationship: location_of CCO:B0057378 ! MIRO1_HUMAN relationship: location_of CCO:B0058142 ! MUL1_HUMAN [Term] id: CCO:C0001195 name: intrinsic to nuclear outer membrane namespace: cellular_component def: "Located in the nuclear outer membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031308 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001872 ! nuclear membrane part relationship: part_of CCO:C0000257 ! nuclear outer membrane [Term] id: CCO:C0001196 name: integral to nuclear outer membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the nuclear outer membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031309 is_a: CCO:C0001188 ! integral to organelle membrane is_a: CCO:C0001195 ! intrinsic to nuclear outer membrane [Term] id: CCO:C0001197 name: intrinsic to vacuolar membrane namespace: cellular_component def: "Located in the vacuolar membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031310 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001856 ! vacuolar part relationship: part_of CCO:C0000356 ! vacuolar membrane [Term] id: CCO:C0001198 name: intrinsic to contractile vacuolar membrane namespace: cellular_component def: "Located in the contractile vacuolar membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031311 is_a: CCO:C0001197 ! intrinsic to vacuolar membrane relationship: part_of CCO:C0001138 ! contractile vacuolar membrane [Term] id: CCO:C0001199 name: extrinsic to organelle membrane namespace: cellular_component def: "Loosely bound to one surface of an organelle membrane, but not integrated into the hydrophobic region." [GOC:mah] xref: GO:0031312 is_a: CCO:C0000900 ! extrinsic to membrane is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0001127 ! organelle membrane [Term] id: CCO:C0001200 name: extrinsic to endosome membrane namespace: cellular_component def: "Loosely bound to one surface of the endosome membrane, but not integrated into the hydrophobic region." [GOC:mah] xref: GO:0031313 is_a: CCO:C0001199 ! extrinsic to organelle membrane is_a: CCO:C0001859 ! endosomal part relationship: part_of CCO:C0000713 ! endosome membrane [Term] id: CCO:C0001201 name: extrinsic to mitochondrial inner membrane namespace: cellular_component def: "Loosely bound to one surface of the mitochondrial inner membrane, but not integrated into the hydrophobic region." [GOC:mah] xref: GO:0031314 is_a: CCO:C0001199 ! extrinsic to organelle membrane is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0001202 name: extrinsic to mitochondrial outer membrane namespace: cellular_component def: "Loosely bound to one surface of the mitochondrial outer membrane, but not integrated into the hydrophobic region." [GOC:mah] xref: GO:0031315 is_a: CCO:C0001199 ! extrinsic to organelle membrane is_a: CCO:C0001874 ! mitochondrial membrane part [Term] id: CCO:C0001203 name: extrinsic to nuclear outer membrane namespace: cellular_component def: "Loosely bound to one surface of the nuclear outer membrane, but not integrated into the hydrophobic region." [GOC:mah] xref: GO:0031316 is_a: CCO:C0001199 ! extrinsic to organelle membrane is_a: CCO:C0001872 ! nuclear membrane part relationship: part_of CCO:C0000257 ! nuclear outer membrane [Term] id: CCO:C0001204 name: tripartite ATP-independent periplasmic transporter complex namespace: cellular_component def: "A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using enery from ion gradients." [GOC:mlg] subset: gosubset_prok synonym: "TRAP transporter complex" EXACT [] synonym: "TRAP-T transporter complex" EXACT [] xref: GO:0031317 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001205 name: RNAi effector complex namespace: cellular_component def: "Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins." [GOC:mah, PMID:14704433] subset: goslim_pir xref: GO:0031332 is_a: CCO:C0001019 ! ribonucleoprotein complex [Term] id: CCO:C0001206 name: intrinsic to plastid membrane namespace: cellular_component def: "Located in a plastid membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031350 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0001634 ! plastid membrane [Term] id: CCO:C0001207 name: integral to plastid membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a plastid membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031351 is_a: CCO:C0001188 ! integral to organelle membrane is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0001634 ! plastid membrane [Term] id: CCO:C0001208 name: intrinsic to plastid inner membrane namespace: cellular_component def: "Located in a plastid inner membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031352 is_a: CCO:C0001206 ! intrinsic to plastid membrane relationship: part_of CCO:C0000656 ! plastid inner membrane [Term] id: CCO:C0001209 name: integral to plastid inner membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a plastid inner membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031353 is_a: CCO:C0001207 ! integral to plastid membrane relationship: part_of CCO:C0000656 ! plastid inner membrane [Term] id: CCO:C0001210 name: intrinsic to plastid outer membrane namespace: cellular_component def: "Located in a plastid outer membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031354 is_a: CCO:C0001206 ! intrinsic to plastid membrane relationship: part_of CCO:C0000655 ! plastid outer membrane [Term] id: CCO:C0001211 name: integral to plastid outer membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a plastid outer membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031355 is_a: CCO:C0001207 ! integral to plastid membrane relationship: part_of CCO:C0000655 ! plastid outer membrane [Term] id: CCO:C0001212 name: intrinsic to chloroplast inner membrane namespace: cellular_component def: "Located in the chloroplast inner membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031356 is_a: CCO:C0001208 ! intrinsic to plastid inner membrane is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000694 ! chloroplast inner membrane [Term] id: CCO:C0001213 name: integral to chloroplast inner membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the chloroplast inner membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031357 is_a: CCO:C0001209 ! integral to plastid inner membrane is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000694 ! chloroplast inner membrane [Term] id: CCO:C0001214 name: intrinsic to chloroplast outer membrane namespace: cellular_component def: "Located in the chloroplast outer membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031358 is_a: CCO:C0001210 ! intrinsic to plastid outer membrane is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000695 ! chloroplast outer membrane [Term] id: CCO:C0001215 name: integral to chloroplast outer membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the chloroplast outer membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031359 is_a: CCO:C0001211 ! integral to plastid outer membrane is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000695 ! chloroplast outer membrane [Term] id: CCO:C0001216 name: intrinsic to thylakoid membrane namespace: cellular_component def: "Located in a thylakoid membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane." [GOC:mah] xref: GO:0031360 is_a: CCO:C0001187 ! intrinsic to organelle membrane is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0001684 ! thylakoid membrane [Term] id: CCO:C0001217 name: integral to thylakoid membrane namespace: cellular_component def: "Penetrating at least one phospholipid bilayer of a thylakoid membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0031361 is_a: CCO:C0001188 ! integral to organelle membrane is_a: CCO:C0001855 ! thylakoid part relationship: part_of CCO:C0001684 ! thylakoid membrane [Term] id: CCO:C0001218 name: anchored to external side of plasma membrane namespace: cellular_component def: "Tethered to the plasma membrane by a covalently attached anchor, such as a lipid moiety, that is embedded in the membrane, with the bulk of the gene product located on the side opposite to the side that faces the cytoplasm. When used to describe a protein, indicates that the peptide sequence does not span the membrane." [GOC:mah] xref: GO:0031362 is_a: CCO:C0001157 ! intrinsic to external side of plasma membrane is_a: CCO:C0001959 ! anchored to plasma membrane relationship: location_of CCO:B0055177 ! CD24_HUMAN relationship: location_of CCO:B0057919 ! PKHD1_HUMAN [Term] id: CCO:C0001219 name: ubiquitin conjugating enzyme complex namespace: cellular_component def: "Any complex that possesses ubiquitin conjugating enzyme activity." [GOC:mah] subset: goslim_pir synonym: "E2 complex" RELATED [] xref: GO:0031371 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001752 ! UB2V1_HUMAN relationship: location_of CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:C0001220 name: UBC13-MMS2 complex namespace: cellular_component def: "A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p." [GOC:mah, PMID:15772086] xref: GO:0031372 is_a: CCO:C0001219 ! ubiquitin conjugating enzyme complex relationship: location_of CCO:B0001813 ! UB2V2_HUMAN relationship: location_of CCO:B0005869 ! UBE2N_HUMAN [Term] id: CCO:C0001221 name: cytosolic fatty acid synthase complex namespace: cellular_component def: "A fatty acid synthase complex located in the cytosol." [GOC:mah] synonym: "cytosolic FAS complex" EXACT [] xref: GO:0031373 is_a: CCO:C0000403 ! fatty acid synthase complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0001222 name: cytosolic type I fatty acid synthase complex namespace: cellular_component def: "A cytosolic fatty acid synthase complex in which each polypeptide chain contains several different catalytic sites." [GOC:mah, ISBN:0471331309 "Biochemical Pathways", ISBN:0716720094, PMID:12957385] synonym: "cytosolic type I FAS complex" EXACT [] xref: GO:0031374 is_a: CCO:C0001221 ! cytosolic fatty acid synthase complex [Term] id: CCO:C0001223 name: type II fatty acid synthase complex namespace: cellular_component def: "A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity." [GOC:mah, ISBN:0471331309 "Biochemical Pathways", ISBN:0716720094, PMID:12957385] synonym: "type II FAS" EXACT [] synonym: "type II FAS complex" EXACT [] synonym: "type II fatty acid synthase" EXACT [] xref: GO:0031375 is_a: CCO:C0000403 ! fatty acid synthase complex [Term] id: CCO:C0001224 name: cytosolic type II fatty acid synthase complex namespace: cellular_component def: "A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol." [GOC:mah, ISBN:0471331309 "Biochemical Pathways", ISBN:0716720094, PMID:12957385] synonym: "cytosolic type II FAS complex" EXACT [] xref: GO:0031376 is_a: CCO:C0001221 ! cytosolic fatty acid synthase complex is_a: CCO:C0001223 ! type II fatty acid synthase complex [Term] id: CCO:C0001225 name: mitochondrial type II fatty acid synthase complex namespace: cellular_component def: "A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion." [GOC:mah, ISBN:0471331309 "Biochemical Pathways", ISBN:0716720094, PMID:12957385] synonym: "mitochondrial type II FAS complex" EXACT [] xref: GO:0031377 is_a: CCO:C0001223 ! type II fatty acid synthase complex is_a: CCO:C0001848 ! mitochondrial part [Term] id: CCO:C0001226 name: plastid type II fatty acid synthase complex namespace: cellular_component def: "A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid." [GOC:mah, ISBN:0471331309 "Biochemical Pathways", ISBN:0716720094, PMID:12957385] synonym: "plastid type II FAS complex" EXACT [] xref: GO:0031378 is_a: CCO:C0001223 ! type II fatty acid synthase complex is_a: CCO:C0001854 ! plastid part [Term] id: CCO:C0001227 name: RNA-directed RNA polymerase complex namespace: cellular_component def: "A protein complex that possesses RNA-directed RNA polymerase activity." [GOC:mah] xref: GO:0031379 is_a: CCO:C0001068 ! RNA polymerase complex [Term] id: CCO:C0001228 name: nuclear RNA-directed RNA polymerase complex namespace: cellular_component def: "A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain." [GOC:vw, PMID:15607976] synonym: "Rdr1 complex" NARROW [] synonym: "RDRC" EXACT [] xref: GO:0031380 is_a: CCO:C0001227 ! RNA-directed RNA polymerase complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001229 name: viral RNA-directed RNA polymerase complex namespace: cellular_component def: "A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus." [GOC:mah, PMID:15574411, PMID:15613301] xref: GO:0031381 is_a: CCO:C0001227 ! RNA-directed RNA polymerase complex [Term] id: CCO:C0001230 name: MPF complex namespace: cellular_component def: "A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC)." [PMID:12045216] xref: GO:0031387 is_a: CCO:C0000053 ! cyclin-dependent protein kinase holoenzyme complex [Term] id: CCO:C0001231 name: Rad17 RFC-like complex namespace: cellular_component def: "A pentameric complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Saccharomyces the subunits are known as Rad17p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p." [PMID:14614842] synonym: "Rad17-RFC" EXACT [] synonym: "Rad17-RLC" EXACT [] synonym: "RFC (Rad17)" EXACT [] xref: GO:0031389 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0001232 name: Ctf18 RFC-like complex namespace: cellular_component def: "A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p." [PMID:14614842] synonym: "Ctf18-RFC" EXACT [] synonym: "Ctf18-RLC" EXACT [] synonym: "RFC (Ctf18)" EXACT [] xref: GO:0031390 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0001233 name: Elg1 RFC-like complex namespace: cellular_component def: "A pentameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p." [PMID:14614842] synonym: "Elg1-RFC" EXACT [] synonym: "Elg1-RLC" EXACT [] synonym: "RFC (Elg1)" EXACT [] xref: GO:0031391 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0001234 name: bursicon neuropeptide hormone complex namespace: cellular_component def: "A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits." [GOC:rc] xref: GO:0031395 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0001235 name: cytoplasmic vesicle namespace: cellular_component def: "A vesicle formed of membrane or protein, found in the cytoplasm of a cell." [GOC:mah] subset: gosubset_prok xref: GO:0031410 is_a: CCO:C0001374 ! vesicle is_a: CCO:C0001745 ! intracellular organelle is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0005448 ! CLCA_HUMAN relationship: location_of CCO:B0006281 ! MLP3A_HUMAN relationship: location_of CCO:B0006342 ! MLP3B_HUMAN relationship: location_of CCO:B0010653 ! ATM_HUMAN-Phosphothreonine72 relationship: location_of CCO:B0011260 ! CLH2_HUMAN-Phosphothreonine103 relationship: location_of CCO:B0011886 ! FNBP1_HUMAN-Phosphoserine296 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013339 ! P3C2A_HUMAN-Phosphoserine259 relationship: location_of CCO:B0014052 ! SH3B4_HUMAN-Phosphoserine637 relationship: location_of CCO:B0019513 ! TAOK2_HUMAN relationship: location_of CCO:B0020052 ! CHIC2_HUMAN relationship: location_of CCO:B0022559 ! SLAP2_HUMAN relationship: location_of CCO:B0027730 ! SIN1_HUMAN relationship: location_of CCO:B0028292 ! DLL1_HUMAN relationship: location_of CCO:B0028600 ! APOA1_HUMAN relationship: location_of CCO:B0030164 ! TLR1_HUMAN relationship: location_of CCO:B0030172 ! TLR6_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0039367 ! COPA_HUMAN-Phosphotyrosine249 relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0042225 ! GRM4_HUMAN relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0049929 ! SRBP1_HUMAN relationship: location_of CCO:B0052789 ! SRBP2_HUMAN-Phosphotyrosine840 relationship: location_of CCO:B0054941 ! DOPO_HUMAN relationship: location_of CCO:B0055232 ! NEUT_HUMAN relationship: location_of CCO:B0055318 ! V1AR_HUMAN relationship: location_of CCO:B0055487 ! NUPL_HUMAN relationship: location_of CCO:B0055781 ! AMPE_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0057194 ! SPRE2_HUMAN relationship: location_of CCO:B0057312 ! MIB1_HUMAN relationship: location_of CCO:B0057324 ! ZDH17_HUMAN relationship: location_of CCO:B0057408 ! RGDSR_HUMAN relationship: location_of CCO:B0058066 ! AP3S1_HUMAN relationship: location_of CCO:B0058128 ! NKD2_HUMAN relationship: location_of CCO:B0058157 ! RAB37_HUMAN relationship: location_of CCO:B0058996 ! GPC5B_HUMAN relationship: location_of CCO:B0059328 ! NSG2_HUMAN relationship: location_of CCO:B0059343 ! GRIP1_HUMAN relationship: location_of CCO:B0062791 ! NECP2_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062957 ! PHLA1_HUMAN relationship: location_of CCO:B0062988 ! COPB_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063008 ! WIPF1_HUMAN relationship: location_of CCO:B0063204 ! AP1B1_HUMAN relationship: location_of CCO:B0063531 ! CLCB_HUMAN relationship: location_of CCO:B0064382 ! CLIC4_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0064623 ! DAB2_HUMAN-Phosphoserine401 relationship: location_of CCO:B0065618 ! AMOT_HUMAN-Phosphoserine312 relationship: location_of CCO:B0065658 ! AP1M1_HUMAN-Phosphothreonine152 relationship: location_of CCO:B0065662 ! AP2A1_HUMAN-Phosphothreonine653 relationship: location_of CCO:B0065667 ! AP3B1_HUMAN-Phosphoserine609 relationship: location_of CCO:B0065817 ! CALY_HUMAN-Phosphotyrosine151 relationship: location_of CCO:B0066020 ! EPN4_HUMAN-Phosphoserine232 relationship: location_of CCO:B0066539 ! GPC5C_HUMAN-Phosphoserine398 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0068796 ! NOSTN_HUMAN-Phosphothreonine174 relationship: location_of CCO:B0068994 ! OREX_HUMAN-Methionine amide97 relationship: location_of CCO:B0069665 ! RAB13_HUMAN-Phosphoserine178 relationship: location_of CCO:B0069696 ! RAB7A_HUMAN-Cysteine methyl ester207 relationship: location_of CCO:B0069720 ! RAI3_HUMAN-Phosphotyrosine347 relationship: location_of CCO:B0069957 ! RHG21_HUMAN-Phosphoserine458 relationship: location_of CCO:B0070341 ! SCAP_HUMAN-Phosphotyrosine243 relationship: location_of CCO:B0070707 ! SNTB2_HUMAN-Phosphothreonine201 relationship: location_of CCO:B0071528 ! TRAF7_HUMAN-Phosphoserine91 [Term] id: CCO:C0001236 name: gas vesicle namespace: cellular_component def: "A hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content aquatic microbes are able to perform vertical migrations." [PMID:8177173] subset: gosubset_prok xref: GO:0031411 is_a: CCO:C0001235 ! cytoplasmic vesicle is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle [Term] id: CCO:C0001237 name: N-terminal protein acetyltransferase complex namespace: cellular_component def: "A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule." [GOC:mah] synonym: "NAT complex" EXACT [] xref: GO:0031414 is_a: CCO:C0001169 ! protein acetyltransferase complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001238 name: NatA complex namespace: cellular_component def: "A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins." [PMID:12890471] synonym: "N-terminal acetyltransferase A complex" EXACT [] xref: GO:0031415 is_a: CCO:C0001237 ! N-terminal protein acetyltransferase complex [Term] id: CCO:C0001239 name: NatB complex namespace: cellular_component def: "A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p." [PMID:12890471] synonym: "N-terminal acetyltransferase B complex" EXACT [] xref: GO:0031416 is_a: CCO:C0001237 ! N-terminal protein acetyltransferase complex [Term] id: CCO:C0001240 name: NatC complex namespace: cellular_component def: "A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p." [PMID:12890471] synonym: "N-terminal acetyltransferase C complex" EXACT [] xref: GO:0031417 is_a: CCO:C0001237 ! N-terminal protein acetyltransferase complex [Term] id: CCO:C0001241 name: invertasome namespace: cellular_component def: "A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts." [PMID:11114897, PMID:9732277] xref: GO:0031421 is_a: CCO:C0001494 ! protein-DNA complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001242 name: RecQ helicase-Topo III complex namespace: cellular_component def: "A complex containing a RecQ family helicase and a topoisomerase III homologue; may also include one or more additional proteins; conserved from E. coli to human." [PMID:15889139] synonym: "Sgs1-Top3 complex" NARROW [] xref: GO:0031422 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0001243 name: box C/D snoRNP complex namespace: cellular_component def: "A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type." [ISBN:0879695897] xref: GO:0031428 is_a: CCO:C0000322 ! small nucleolar ribonucleoprotein complex is_a: CCO:C0001871 ! nucleolar part [Term] id: CCO:C0001244 name: box H/ACA snoRNP complex namespace: cellular_component def: "A ribonucleoprotein complex containing small nucleolar RNA of the box H/ACA type." [ISBN:0879695897] xref: GO:0031429 is_a: CCO:C0000322 ! small nucleolar ribonucleoprotein complex is_a: CCO:C0001871 ! nucleolar part [Term] id: CCO:C0001245 name: M band namespace: cellular_component def: "The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines." [GOC:mtg_muscle, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815316194] synonym: "M disc" EXACT [] synonym: "M line" NARROW [] synonym: "mesophragma" EXACT [] synonym: "midline" BROAD [] xref: GO:0031430 is_a: CCO:C0001868 ! contractile fiber part relationship: part_of CCO:C0001326 ! A band [Term] id: CCO:C0001246 name: Dbf4-dependent protein kinase complex namespace: cellular_component def: "A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins." [PMID:12045100] synonym: "Cdc7-Dbf4 complex" NARROW [] synonym: "DDK" EXACT [] synonym: "Hsk1-Dfp1 kinase complex" NARROW [] xref: GO:0031431 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001247 name: BRCA1-BARD1 complex namespace: cellular_component def: "A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage." [PMID:12787778] xref: GO:0031436 is_a: CCO:C0000027 ! nuclear ubiquitin ligase complex relationship: location_of CCO:B0002086 ! BARD1_HUMAN relationship: location_of CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 [Term] id: CCO:C0001248 name: cullin-RING ubiquitin ligase complex namespace: cellular_component def: "Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity." [PMID:15571813, PMID:15688063] synonym: "CRL complex" EXACT [] synonym: "cullin complex" EXACT [] synonym: "cullin-RING ligase" RELATED [] xref: GO:0031461 is_a: CCO:C0000026 ! ubiquitin ligase complex relationship: location_of CCO:B0001759 ! CUL1_HUMAN relationship: location_of CCO:B0001760 ! CUL2_HUMAN relationship: location_of CCO:B0001763 ! CUL4B_HUMAN relationship: location_of CCO:B0001888 ! Q5TCY3_HUMAN relationship: location_of CCO:B0001949 ! PARC_HUMAN relationship: location_of CCO:B0002027 ! CUL5_HUMAN relationship: location_of CCO:B0010521 ! ANC2_HUMAN-Phosphoserine218 relationship: location_of CCO:B0011413 ! CUL3_HUMAN-Phosphoserine737 relationship: location_of CCO:B0064589 ! CUL4A_HUMAN-Phosphoserine10 relationship: location_of CCO:B0065913 ! CUL7_HUMAN-Phosphoserine329 [Term] id: CCO:C0001249 name: Cul2-RING ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein." [PMID:15571813, PMID:15688063] synonym: "CBC complex" BROAD [] synonym: "CDL2 complex" EXACT [] synonym: "CRL2 complex" EXACT [] synonym: "cullin-RING ligase 2" EXACT [] synonym: "EC2S complex" BROAD [] synonym: "ECS complex" BROAD [] synonym: "SCF2 complex" RELATED [] synonym: "VBC complex" NARROW [] xref: GO:0031462 is_a: CCO:C0001248 ! cullin-RING ubiquitin ligase complex [Term] id: CCO:C0001250 name: Cul3-RING ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein." [PMID:15571813, PMID:15688063] synonym: "BC3B complex" EXACT [] synonym: "BCR3 complex" EXACT [] synonym: "CDL3 complex" EXACT [] synonym: "CRL3 complex" EXACT [] synonym: "cullin-RING ligase 3" EXACT [] synonym: "SCF3 complex" RELATED [] xref: GO:0031463 is_a: CCO:C0001248 ! cullin-RING ubiquitin ligase complex [Term] id: CCO:C0001251 name: Cul4A-RING ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein." [PMID:15571813, PMID:15688063] synonym: "CDL4 complex" EXACT [] synonym: "CRL4 complex" EXACT [] synonym: "cullin-RING ligase 4A" EXACT [] synonym: "DCX complex" EXACT [] synonym: "SCF4 complex" RELATED [] synonym: "VDC complex" NARROW [] xref: GO:0031464 is_a: CCO:C0001248 ! cullin-RING ubiquitin ligase complex [Term] id: CCO:C0001252 name: Cul4B-RING ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits." [PMID:15571813, PMID:15688063] synonym: "cullin-RING ligase 4B" EXACT [] xref: GO:0031465 is_a: CCO:C0001248 ! cullin-RING ubiquitin ligase complex [Term] id: CCO:C0001253 name: Cul5-RING ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein." [PMID:15571813, PMID:15688063] synonym: "CDL5 complex" EXACT [] synonym: "CRL5 complex" EXACT [] synonym: "cullin-RING ligase 5" EXACT [] synonym: "EC2S complex" BROAD [] synonym: "SCF5 complex" RELATED [] xref: GO:0031466 is_a: CCO:C0001248 ! cullin-RING ubiquitin ligase complex [Term] id: CCO:C0001254 name: Cul7-RING ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein." [PMID:15571813, PMID:15688063] synonym: "CDL7 complex" EXACT [] synonym: "CRL7 complex" EXACT [] synonym: "cullin-RING ligase 7" EXACT [] synonym: "SCF7 complex" EXACT [] xref: GO:0031467 is_a: CCO:C0001248 ! cullin-RING ubiquitin ligase complex [Term] id: CCO:C0001255 name: polyhedral organelle namespace: cellular_component def: "An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy." [GOC:js, PMID:10498708, PMID:11844753, PMID:12923081] subset: goslim_pir subset: gosubset_prok xref: GO:0031469 is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle [Term] id: CCO:C0001256 name: carboxysome namespace: cellular_component def: "An organelle found in the Cyanobacteria consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide including mechanisms for the concentration of carbonate to increase the efficiency of fixation under low-carbon dioxide conditions." [GOC:js, PMID:8157606, PMID:8491708] subset: gosubset_prok xref: GO:0031470 is_a: CCO:C0001255 ! polyhedral organelle [Term] id: CCO:C0001257 name: ethanolamine degradation polyhedral organelle namespace: cellular_component def: "An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase." [GOC:js, PMID:11844753] subset: gosubset_prok synonym: "ethanolamine metabolosome" RELATED [] xref: GO:0031471 is_a: CCO:C0001255 ! polyhedral organelle [Term] id: CCO:C0001258 name: propanediol degradation polyhedral organelle namespace: cellular_component def: "An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase." [GOC:js, PMID:10498708, PMID:11844753, PMID:12923081] subset: gosubset_prok xref: GO:0031472 is_a: CCO:C0001255 ! polyhedral organelle [Term] id: CCO:C0001259 name: myosin IV complex namespace: cellular_component def: "A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031474 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001260 name: myosin V complex namespace: cellular_component def: "A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localisation and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031475 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001261 name: myosin VI complex namespace: cellular_component def: "A myosin complex containing a dimer of class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031476 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001262 name: myosin VII complex namespace: cellular_component def: "A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031477 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001263 name: myosin VIII complex namespace: cellular_component def: "A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031478 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001264 name: myosin IX complex namespace: cellular_component def: "A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031479 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001265 name: myosin X complex namespace: cellular_component def: "A myosin complex containing one or more class X myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031480 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001266 name: myosin XI complex namespace: cellular_component def: "A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031481 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001267 name: myosin XII complex namespace: cellular_component def: "A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031482 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001268 name: myosin XIII complex namespace: cellular_component def: "A myosin complex containing one or more class XIII myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031483 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001269 name: myosin XIV complex namespace: cellular_component def: "A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031484 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001270 name: myosin XV complex namespace: cellular_component def: "A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031485 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001271 name: myosin XVI complex namespace: cellular_component def: "A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, PMID:11294886] xref: GO:0031486 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001272 name: myosin XVII complex namespace: cellular_component def: "A myosin complex containing one or more class XVII myosin heavy chains and associated light chains." [http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031487 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001273 name: myosin XVIII complex namespace: cellular_component def: "A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain." [PMID:11294886] xref: GO:0031488 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001274 name: TRAMP complex namespace: cellular_component def: "A multiprotein complex, which in yeast consists of Trf4p, Air1p or Air2p and Mtr4p. This nuclear RNA surveillance and quality control complex is involved in the distributive polyadenylation of substrates that include: hypomodified and incorrectly folded tRNAs, snoRNA precursors and rRNA precursors. It is also required for the degradative activity of the nuclear exosome in vivo." [PMID:15828860, PMID:15935758] synonym: "Trf4 complex" EXACT [] synonym: "Trf4 poly(A) polymerase complex" EXACT [] synonym: "Trf4p-Air2p-Mtr4p polyadenylation complex" EXACT [] xref: GO:0031499 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001275 name: Tea1 cell-end complex namespace: cellular_component def: "A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity." [PMID:15936270] xref: GO:0031500 is_a: CCO:C0000435 ! microtubule associated complex relationship: part_of CCO:C0000017 ! polarisome [Term] id: CCO:C0001276 name: mannosyltransferase complex namespace: cellular_component def: "A complex that posseses mannosyltransferase activity." [GOC:mah] subset: goslim_pir xref: GO:0031501 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001277 name: dolichyl-phosphate-mannose-protein mannosyltransferase complex namespace: cellular_component def: "A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies." [GOC:mah, PMID:15948957] synonym: "PMT family mannosyltransferase complex" RELATED [] synonym: "protein O-mannosyltransferase complex" EXACT [] xref: GO:0031502 is_a: CCO:C0001276 ! mannosyltransferase complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0001278 name: SUMO activating enzyme complex namespace: cellular_component def: "A conserved heterodimeric complex with SUMO activating enzyme activity." [PMID:15601841] synonym: "SAE" EXACT [] synonym: "SUMO E1 activator enzyme complex" EXACT [] xref: GO:0031510 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001279 name: Mis6-Sim4 complex namespace: cellular_component def: "A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human." [GOC:vw, PMID:12719471, PMID:15897182] synonym: "Mis6 centromere subcomplex" NARROW [] synonym: "Sim4 complex" EXACT [] xref: GO:0031511 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000158 ! inner kinetochore of condensed chromosome [Term] id: CCO:C0001280 name: motile primary cilium namespace: cellular_component def: "A specialized primary cilium that contains a 9 + 0 arrangement of microtubules, radial spokes, and a dynein apparatus, but no inner doublet microtubules. Motile primary cilia display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface." [GOC:kva] xref: GO:0031512 is_a: CCO:C0000481 ! cilium relationship: location_of CCO:B0001618 ! LIS1_HUMAN [Term] id: CCO:C0001281 name: nonmotile primary cilium namespace: cellular_component def: "An immotile primary cilium that may be missing the central pair of microtubules, or the central pair of microtubules and outer dynein arms. Some primary cilia also have altered arrangements of outer microtubules (fewer than nine and/or not always present as doublets). Nonmotile primary cilia typically function as sensory organelles that concentrate and organize sensory signaling molecules." [GOC:kna] xref: GO:0031513 is_a: CCO:C0000481 ! cilium relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0032548 ! RAB8A_HUMAN relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: location_of CCO:B0050794 ! SSR3_HUMAN relationship: location_of CCO:B0058444 ! MCHR1_HUMAN [Term] id: CCO:C0001282 name: motile secondary cilium namespace: cellular_component def: "A cilium that consists of a 9 + 2 arrangement of microtubules, radial spokes, and a dynein apparatus. Motile cilia, found on cells that line the lumenal ducts of various tissues, beat with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface." [GOC:kva] xref: GO:0031514 is_a: CCO:C0000481 ! cilium relationship: location_of CCO:B0043419 ! BBS2_HUMAN relationship: location_of CCO:B0043836 ! BBS4_HUMAN [Term] id: CCO:C0001283 name: tRNA (m1A) methyltransferase complex namespace: cellular_component def: "A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer." [PMID:10779558, PMID:14739239] subset: gosubset_prok xref: GO:0031515 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001781 ! tRNA methyltransferase complex [Term] id: CCO:C0001284 name: CBF3 complex namespace: cellular_component def: "A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p." [PMID:13679521, PMID:9407032] xref: GO:0031518 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0002168 ! chromosome, centromeric region [Term] id: CCO:C0001285 name: PcG protein complex namespace: cellular_component def: "A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure." [PMID:9372908] subset: goslim_pir synonym: "Polycomb Group protein complex" EXACT [] xref: GO:0031519 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0002111 ! PCGF6_HUMAN relationship: location_of CCO:B0014560 ! TYY1_HUMAN-Phosphoserine184 relationship: location_of CCO:B0020553 ! RING1_HUMAN relationship: location_of CCO:B0064109 ! CBX8_HUMAN-Phosphoserine332 [Term] id: CCO:C0001286 name: plasma membrane of cell tip namespace: cellular_component def: "The portion of the plasma membrane surrounding the cell tip." [GOC:mah] xref: GO:0031520 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0002013 ! cell tip [Term] id: CCO:C0001287 name: spitzenkorper namespace: cellular_component def: "Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments." [PMID:15701784, PMID:15976451] xref: GO:0031521 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0000166 ! hyphal tip [Term] id: CCO:C0001289 name: Myb complex namespace: cellular_component def: "A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression." [PMID:12490953, PMID:15545624] synonym: "Myeloblastosis proto-oncogene protein complex" EXACT [] xref: GO:0031523 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0001290 name: brush border membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the brush border." [GOC:mah] xref: GO:0031526 is_a: CCO:C0001173 ! cell projection membrane relationship: location_of CCO:B0020561 ! PLD2_HUMAN relationship: location_of CCO:B0055034 ! B4GT1_HUMAN relationship: location_of CCO:B0055140 ! DRD5_HUMAN relationship: location_of CCO:B0058002 ! ITLN1_HUMAN relationship: part_of CCO:C0000460 ! brush border [Term] id: CCO:C0001291 name: filopodium membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a filopodium." [GOC:mah] xref: GO:0031527 is_a: CCO:C0001173 ! cell projection membrane relationship: part_of CCO:C0000989 ! filopodium [Term] id: CCO:C0001292 name: microvillus membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a microvillus." [GOC:mah] xref: GO:0031528 is_a: CCO:C0001173 ! cell projection membrane relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: part_of CCO:C0000459 ! microvillus [Term] id: CCO:C0001293 name: mRNA capping enzyme complex namespace: cellular_component def: "A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in Sz. pombe) and is involved in mRNA capping." [GOC:vw, PMID:10347220] synonym: "mRNA (guanine-N7) methyltransferase complex" EXACT [] synonym: "mRNA cap methyltransferase complex" EXACT [] xref: GO:0031533 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001294 name: cellular bud neck polarisome namespace: cellular_component def: "Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis." [PMID:9632790] xref: GO:0031560 is_a: CCO:C0000017 ! polarisome relationship: part_of CCO:C0000487 ! cellular bud neck [Term] id: CCO:C0001295 name: cellular bud tip polarisome namespace: cellular_component def: "Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud." [PMID:9632790] xref: GO:0031561 is_a: CCO:C0000017 ! polarisome relationship: part_of CCO:C0000486 ! cellular bud tip [Term] id: CCO:C0001296 name: hyphal tip polarisome namespace: cellular_component def: "Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha." [PMID:15976451] xref: GO:0031562 is_a: CCO:C0000017 ! polarisome relationship: part_of CCO:C0000166 ! hyphal tip [Term] id: CCO:C0001297 name: mating projection tip polarisome namespace: cellular_component def: "Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone." [PMID:14734532] xref: GO:0031563 is_a: CCO:C0000017 ! polarisome is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0001770 ! mating projection tip [Term] id: CCO:C0001298 name: AMP-activated protein kinase complex namespace: cellular_component def: "A protein complex that possesses AMP-dependent protein kinase activity." [GOC:mah] synonym: "5'-AMP-activated protein kinase complex" EXACT [] synonym: "Snf1 kinase complex" NARROW [] synonym: "Snf1 serine/threonine protein kinase complex" NARROW [] xref: GO:0031588 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0065241 ! AAKB2_HUMAN-Phosphoserine183 [Term] id: CCO:C0001299 name: centrosomal corona namespace: cellular_component def: "An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin." [GOC:kp, GOC:mah] comment: Note that the centrosomal corona has been observed in Dictyostelium, and is the functional equivalent of pericentriolar material. xref: GO:0031592 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: location_of CCO:B0064372 ! CLAP1_HUMAN-Phosphothreonine656 relationship: part_of CCO:C0000383 ! centrosome [Term] id: CCO:C0001300 name: neuromuscular junction namespace: cellular_component def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible of the muscle contraction." [GOC:nln] xref: GO:0031594 is_a: CCO:C0001900 ! synapse relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0068681 ! NFM_HUMAN-Phosphoserine654 [Term] id: CCO:C0001301 name: nuclear proteasome complex namespace: cellular_component def: "A proteasome found in the nucleus of a cell." [GOC:mah] xref: GO:0031595 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002078 ! proteasome complex [Term] id: CCO:C0001302 name: ER proteasome complex namespace: cellular_component def: "A proteasome found in the endoplasmic reticulum of a cell." [GOC:mah] xref: GO:0031596 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0002078 ! proteasome complex [Term] id: CCO:C0001304 name: nuclear proteasome regulatory particle namespace: cellular_component def: "The regulatory subcomplex of a proteasome located in the nucleus of a cell." [GOC:mah] xref: GO:0031598 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002079 ! proteasome regulatory particle relationship: part_of CCO:C0001301 ! nuclear proteasome complex [Term] id: CCO:C0001305 name: ER proteasome regulatory particle namespace: cellular_component def: "The regulatory subcomplex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] xref: GO:0031599 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0002079 ! proteasome regulatory particle relationship: part_of CCO:C0001302 ! ER proteasome complex [Term] id: CCO:C0001307 name: nuclear proteasome core complex namespace: cellular_component def: "The core complex of a proteasome located in the nucleus of a cell." [GOC:mah] xref: GO:0031601 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002080 ! proteasome core complex relationship: part_of CCO:C0001301 ! nuclear proteasome complex [Term] id: CCO:C0001308 name: ER proteasome core complex namespace: cellular_component def: "The core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] xref: GO:0031602 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0002080 ! proteasome core complex relationship: part_of CCO:C0001302 ! ER proteasome complex [Term] id: CCO:C0001310 name: nuclear proteasome core complex, alpha-subunit complex namespace: cellular_component def: "The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell." [GOC:mah] xref: GO:0031604 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002083 ! proteasome core complex, alpha-subunit complex relationship: part_of CCO:C0001307 ! nuclear proteasome core complex [Term] id: CCO:C0001311 name: ER proteasome core complex, alpha-subunit complex namespace: cellular_component def: "The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] xref: GO:0031605 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0002083 ! proteasome core complex, alpha-subunit complex relationship: part_of CCO:C0001308 ! ER proteasome core complex [Term] id: CCO:C0001313 name: nuclear proteasome core complex, beta-subunit complex namespace: cellular_component def: "The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell." [GOC:mah] xref: GO:0031607 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002084 ! proteasome core complex, beta-subunit complex relationship: part_of CCO:C0001307 ! nuclear proteasome core complex [Term] id: CCO:C0001314 name: ER proteasome core complex, beta-subunit complex namespace: cellular_component def: "The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] xref: GO:0031608 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0002084 ! proteasome core complex, beta-subunit complex relationship: part_of CCO:C0001308 ! ER proteasome core complex [Term] id: CCO:C0001316 name: nuclear proteasome regulatory particle, base subcomplex namespace: cellular_component def: "The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell." [GOC:mah] xref: GO:0031610 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002081 ! proteasome regulatory particle, base subcomplex relationship: part_of CCO:C0001304 ! nuclear proteasome regulatory particle [Term] id: CCO:C0001317 name: ER proteasome regulatory particle, base subcomplex namespace: cellular_component def: "The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] xref: GO:0031611 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0002081 ! proteasome regulatory particle, base subcomplex relationship: part_of CCO:C0001305 ! ER proteasome regulatory particle [Term] id: CCO:C0001319 name: nuclear proteasome regulatory particle, lid subcomplex namespace: cellular_component def: "The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell." [GOC:mah] xref: GO:0031613 is_a: CCO:C0001847 ! nuclear part is_a: CCO:C0002082 ! proteasome regulatory particle, lid subcomplex relationship: part_of CCO:C0001304 ! nuclear proteasome regulatory particle [Term] id: CCO:C0001320 name: ER proteasome regulatory particle, lid subcomplex namespace: cellular_component def: "The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell." [GOC:mah] xref: GO:0031614 is_a: CCO:C0001851 ! endoplasmic reticulum part is_a: CCO:C0002082 ! proteasome regulatory particle, lid subcomplex relationship: part_of CCO:C0001305 ! ER proteasome regulatory particle [Term] id: CCO:C0001322 name: spindle pole centrosome namespace: cellular_component def: "A centrosome from which one pole of a mitotic or meiotic spindle is organized." [GOC:mah] xref: GO:0031616 is_a: CCO:C0000383 ! centrosome relationship: location_of CCO:B0013133 ! NDE1_HUMAN-Phosphoserine306 relationship: location_of CCO:B0048231 ! DLGP5_HUMAN-Phosphothreonine401 relationship: part_of CCO:C0000144 ! spindle pole [Term] id: CCO:C0001323 name: NMS complex namespace: cellular_component def: "A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes." [PMID:16079914] synonym: "Ndc80-MIND-Spc7 complex" EXACT [] xref: GO:0031617 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000103 ! kinetochore [Term] id: CCO:C0001325 name: xanthophore namespace: cellular_component def: "A chromatophore containing yellow pigment." [ISBN:0395825172] comment: Note that this term refers to a subcellular structure, and should not be confused with the specialized cells known as xanthophores, which produce yellow pigment and are found in fish and amphibian skin. Note that several terms in the biological process ontology ('xanthophore differentiation ; GO:0050936' and its children) refer to xanthophores in the sense of pigment-producing cells. xref: GO:0031633 is_a: CCO:C0001688 ! chromatophore [Term] id: CCO:C0001326 name: A band namespace: cellular_component def: "The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line." [ISBN:0321204131] synonym: "A disc" EXACT [] synonym: "anisotropic disc" EXACT [] synonym: "Q disc" EXACT [] synonym: "transverse disc" EXACT [] xref: GO:0031672 is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0056023 ! MYPC3_HUMAN relationship: part_of CCO:C0000933 ! sarcomere [Term] id: CCO:C0001327 name: H zone namespace: cellular_component def: "A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments." [GOC:mtg_muscle, ISBN:0321204131] synonym: "H band" EXACT [] synonym: "H disc" EXACT [] xref: GO:0031673 is_a: CCO:C0001868 ! contractile fiber part relationship: part_of CCO:C0001326 ! A band [Term] id: CCO:C0001328 name: I band namespace: cellular_component def: "A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end." [ISBN:0321204131] synonym: "I disc" EXACT [] synonym: "isotropic disc" EXACT [] synonym: "J disc" EXACT [] xref: GO:0031674 is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0015638 ! ACTC_HUMAN relationship: location_of CCO:B0056058 ! ANKR1_HUMAN relationship: part_of CCO:C0000933 ! sarcomere [Term] id: CCO:C0001330 name: plasma membrane-derived thylakoid membrane namespace: cellular_component def: "The pigmented membrane of a plasma membrane-derived thylakoid." [GOC:mah, GOC:mtg_sensu] synonym: "plasma membrane thylakoid membrane" EXACT [] synonym: "thylakoid membrane (sensu Cyanobacteria)" EXACT [] xref: GO:0031676 is_a: CCO:C0001684 ! thylakoid membrane is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000942 ! plasma membrane-derived thylakoid [Term] id: CCO:C0001333 name: G-protein beta/gamma-subunit complex namespace: cellular_component def: "The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange." [GOC:mah] comment: See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'. synonym: "G-beta/G-gamma complex" EXACT [] synonym: "heterotrimeric G-protein GTPase, beta-subunit" NARROW [] xref: GO:0031680 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001334 name: haptoglobin-hemoglobin complex namespace: cellular_component def: "A protein complex formed by the stable binding of a haptoglobin to hemoglobin." [GOC:mah] xref: GO:0031838 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0001335 name: Tic complex namespace: cellular_component def: "The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane." [PMID:12180471, PMID:12393016] synonym: "chloroplast inner membrane translocase complex" EXACT [] xref: GO:0031897 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000694 ! chloroplast inner membrane [Term] id: CCO:C0001336 name: chromoplast envelope namespace: cellular_component def: "The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:pz] xref: GO:0031898 is_a: CCO:C0000654 ! plastid envelope relationship: part_of CCO:C0000638 ! chromoplast [Term] id: CCO:C0001337 name: chromoplast inner membrane namespace: cellular_component def: "The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma." [GOC:pz] xref: GO:0031899 is_a: CCO:C0000656 ! plastid inner membrane is_a: CCO:C0001976 ! chromoplast membrane [Term] id: CCO:C0001338 name: chromoplast outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope." [GOC:pz] xref: GO:0031900 is_a: CCO:C0000655 ! plastid outer membrane is_a: CCO:C0001976 ! chromoplast membrane [Term] id: CCO:C0001339 name: early endosome membrane namespace: cellular_component def: "The lipid bilayer surrounding an early endosome." [GOC:pz] xref: GO:0031901 is_a: CCO:C0000713 ! endosome membrane relationship: location_of CCO:B0001980 ! DP13B_HUMAN relationship: location_of CCO:B0006187 ! SH3G3_HUMAN relationship: location_of CCO:B0006310 ! SH3G1_HUMAN relationship: location_of CCO:B0011567 ! DP13A_HUMAN-Phosphoserine691 relationship: location_of CCO:B0012186 ! HGS_HUMAN-Phosphotyrosine308 relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0023550 ! RAB5C_HUMAN relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0063025 ! EEA1_HUMAN relationship: location_of CCO:B0066332 ! FYV1_HUMAN-Phosphotyrosine1772 relationship: location_of CCO:B0072026 ! ZFY16_HUMAN-Phosphoserine815 relationship: part_of CCO:C0000352 ! early endosome [Term] id: CCO:C0001340 name: late endosome membrane namespace: cellular_component def: "The lipid bilayer surrounding a late endosome." [GOC:pz] xref: GO:0031902 is_a: CCO:C0000713 ! endosome membrane relationship: location_of CCO:B0001692 ! RHOB_HUMAN relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035396 ! PLD1_HUMAN-Phosphoserine629 relationship: location_of CCO:B0037912 ! CLCN3_HUMAN relationship: location_of CCO:B0054939 ! CD63_HUMAN relationship: location_of CCO:B0058166 ! ARL8A_HUMAN relationship: location_of CCO:B0059131 ! MK1I1_HUMAN relationship: location_of CCO:B0062986 ! VPS4A_HUMAN relationship: location_of CCO:B0063398 ! VPS11_HUMAN relationship: location_of CCO:B0068061 ! MCLN1_HUMAN-Phosphoserine547 relationship: part_of CCO:C0000353 ! late endosome [Term] id: CCO:C0001341 name: microbody membrane namespace: cellular_component def: "The lipid bilayer surrounding a microbody." [GOC:mah] xref: GO:0031903 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001652 ! microbody [Term] id: CCO:C0001342 name: endosome lumen namespace: cellular_component def: "The volume enclosed by the membranes of an endosome." [GOC:mah] xref: GO:0031904 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001859 ! endosomal part [Term] id: CCO:C0001343 name: early endosome lumen namespace: cellular_component def: "The volume enclosed by the membranes of an early endosome." [GOC:mah] xref: GO:0031905 is_a: CCO:C0001342 ! endosome lumen relationship: part_of CCO:C0000352 ! early endosome [Term] id: CCO:C0001344 name: late endosome lumen namespace: cellular_component def: "The volume enclosed by the membranes of a late endosome." [GOC:mah] xref: GO:0031906 is_a: CCO:C0001342 ! endosome lumen relationship: part_of CCO:C0000353 ! late endosome [Term] id: CCO:C0001345 name: microbody lumen namespace: cellular_component def: "The volume enclosed by the membranes of a microbody." [GOC:mah] xref: GO:0031907 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001857 ! microbody part [Term] id: CCO:C0001346 name: glyoxysomal lumen namespace: cellular_component def: "The volume enclosed by the membranes of a glyoxysome." [GOC:mah] xref: GO:0031908 is_a: CCO:C0001345 ! microbody lumen relationship: part_of CCO:C0000643 ! glyoxysome [Term] id: CCO:C0001347 name: peroxisomal lumen namespace: cellular_component def: "The volume enclosed by the membranes of a peroxisome." [GOC:mah] xref: GO:0031909 is_a: CCO:C0001345 ! microbody lumen is_a: CCO:C0001858 ! peroxisomal part [Term] id: CCO:C0001348 name: cytostome namespace: cellular_component def: "Stable, specialized structure for the ingestion of food by the cell into phagosomes." [PMID:10503189] xref: GO:0031910 is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001349 name: cytoproct namespace: cellular_component def: "Stable, specialized structure for extrusion of waste by the cell into the surrounding medium." [PMID:10503189] xref: GO:0031911 is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001350 name: oral apparatus namespace: cellular_component def: "Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems." [PMID:10503189] comment: Note that this term refers to a subcellular structure characteristic of ciliate protozoans, and should not be confused with oral anatomical structures of multicellular animals. xref: GO:0031912 is_a: CCO:C0001706 ! cell projection [Term] id: CCO:C0001351 name: contractile vacuole pore namespace: cellular_component def: "Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium." [PMID:10503189] xref: GO:0031913 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001856 ! vacuolar part is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000442 ! actin filament relationship: part_of CCO:C0001138 ! contractile vacuolar membrane [Term] id: CCO:C0001354 name: telomeric heterochromatin namespace: cellular_component def: "Heterochromatic regions of the chromosome found at the telomeres." [GOC:mah] xref: GO:0031933 is_a: CCO:C0000119 ! heterochromatin [Term] id: CCO:C0001355 name: mating-type region heterochromatin namespace: cellular_component def: "Heterochromatic regions of the chromosome found at silenced mating-type loci." [GOC:mah] xref: GO:0031934 is_a: CCO:C0000119 ! heterochromatin [Term] id: CCO:C0001356 name: filamentous actin namespace: cellular_component def: "A two-stranded helical polymer of the protein actin." [GOC:mah] comment: Note that this term refers only to the actin portion of a microfilament, and does not encompass associated proteins. See also the cellular component term 'actin filament ; GO:0005884'. synonym: "F-actin" EXACT [] xref: GO:0031941 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0063063 ! MYO1C_HUMAN relationship: location_of CCO:B0063121 ! MYO1A_HUMAN relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0066163 ! FERM2_HUMAN-Phosphoserine181 relationship: part_of CCO:C0000442 ! actin filament [Term] id: CCO:C0001357 name: i-AAA complex namespace: cellular_component def: "Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases." [PMID:16247555, PMID:16267274] xref: GO:0031942 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0001358 name: nuclear membrane namespace: cellular_component def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz] xref: GO:0031965 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0005282 ! NOC4L_HUMAN relationship: location_of CCO:B0005901 ! BCLX_HUMAN relationship: location_of CCO:B0005981 ! TRI27_HUMAN relationship: location_of CCO:B0010773 ! BCL2_HUMAN-Phosphoserine70 relationship: location_of CCO:B0011719 ! EPC1_HUMAN-Phosphoserine357 relationship: location_of CCO:B0011884 ! FL2D_HUMAN-Phosphoserine306 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0014272 ! SUMO1_HUMAN-Phosphoserine2 relationship: location_of CCO:B0014582 ! UN84B_HUMAN-Phosphoserine38 relationship: location_of CCO:B0033365 ! LASS4_HUMAN relationship: location_of CCO:B0033366 ! LASS3_HUMAN relationship: location_of CCO:B0033369 ! LASS6_HUMAN relationship: location_of CCO:B0035088 ! LASS2_HUMAN-Phosphoserine341 relationship: location_of CCO:B0035094 ! LASS5_HUMAN-Phosphoserine355 relationship: location_of CCO:B0036139 ! SENP2_HUMAN relationship: location_of CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054618 ! PDCD6_HUMAN relationship: location_of CCO:B0055891 ! I15RA_HUMAN relationship: location_of CCO:B0055990 ! S29A2_HUMAN relationship: location_of CCO:B0057421 ! SHSA5_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0061984 ! P121A_HUMAN relationship: location_of CCO:B0062772 ! DD19A_HUMAN relationship: location_of CCO:B0062780 ! NUP54_HUMAN relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0063329 ! PTGDS_HUMAN relationship: location_of CCO:B0064683 ! DD19B_HUMAN-Phosphoserine86 relationship: location_of CCO:B0064798 ! DNJC1_HUMAN-Phosphoserine430 relationship: location_of CCO:B0064897 ! DTL_HUMAN-Phosphoserine676 relationship: location_of CCO:B0066756 ! HAX1_HUMAN-N-acetylserine2 relationship: location_of CCO:B0068941 ! NUP98_HUMAN-Phosphoserine1060 relationship: part_of CCO:C0000253 ! nuclear envelope [Term] id: CCO:C0001359 name: mitochondrial membrane namespace: cellular_component def: "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." [GOC:mah] xref: GO:0031966 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001848 ! mitochondrial part relationship: location_of CCO:B0002253 ! STA13_HUMAN relationship: location_of CCO:B0005422 ! BID_HUMAN relationship: location_of CCO:B0005901 ! BCLX_HUMAN relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010820 ! BNIP3_HUMAN-Phosphoserine86 relationship: location_of CCO:B0014175 ! SPG7_HUMAN-Nitrated tyrosine505 relationship: location_of CCO:B0016489 ! PA24B_HUMAN relationship: location_of CCO:B0025098 ! LETM1_HUMAN relationship: location_of CCO:B0034526 ! AFG32_HUMAN-N6-acetyllysine308 relationship: location_of CCO:B0034583 ! B2L13_HUMAN-Phosphoserine420 relationship: location_of CCO:B0054644 ! NDUS3_HUMAN relationship: location_of CCO:B0055220 ! TSPO_HUMAN relationship: location_of CCO:B0055530 ! CASP7_HUMAN relationship: location_of CCO:B0055978 ! FKBP8_HUMAN relationship: location_of CCO:B0056362 ! AGK_HUMAN relationship: location_of CCO:B0059028 ! NDUAD_HUMAN relationship: location_of CCO:B0059077 ! PEMT_HUMAN relationship: location_of CCO:B0062990 ! SFXN3_HUMAN relationship: location_of CCO:B0063062 ! SFXN1_HUMAN relationship: location_of CCO:B0063244 ! HTRA2_HUMAN relationship: location_of CCO:B0063865 ! BCLW_HUMAN-Phosphoserine192 relationship: location_of CCO:B0068547 ! NDUA6_HUMAN-N-acetylalanine2 relationship: part_of CCO:C0000326 ! mitochondrial envelope [Term] id: CCO:C0001360 name: organelle envelope namespace: cellular_component def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz] subset: gosubset_prok xref: GO:0031967 is_a: CCO:C0001367 ! envelope is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0002127 ! membrane-bounded organelle [Term] id: CCO:C0001361 name: organelle outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of an organelle envelope." [GOC:mah] xref: GO:0031968 is_a: CCO:C0000898 ! outer membrane is_a: CCO:C0001127 ! organelle membrane relationship: part_of CCO:C0001360 ! organelle envelope [Term] id: CCO:C0001362 name: chloroplast membrane namespace: cellular_component def: "Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope." [GOC:mah, GOC:pz] xref: GO:0031969 is_a: CCO:C0001634 ! plastid membrane is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000708 ! chloroplast envelope [Term] id: CCO:C0001363 name: organelle envelope lumen namespace: cellular_component def: "The region between the inner and outer lipid bilayers of an organelle envelope." [GOC:mah] synonym: "organelle intermembrane space" EXACT [] xref: GO:0031970 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0001360 ! organelle envelope [Term] id: CCO:C0001364 name: chloroplast intermembrane space namespace: cellular_component def: "The region between the inner and outer lipid bilayers of a chloroplast envelope." [GOC:mah] synonym: "chloroplast envelope lumen" EXACT [] xref: GO:0031972 is_a: CCO:C0000657 ! plastid intermembrane space is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000708 ! chloroplast envelope [Term] id: CCO:C0001365 name: chromoplast intermembrane space namespace: cellular_component def: "The region between the inner and outer lipid bilayers of a chromoplast envelope." [GOC:mah] synonym: "chromoplast envelope lumen" EXACT [] xref: GO:0031973 is_a: CCO:C0000657 ! plastid intermembrane space relationship: part_of CCO:C0001336 ! chromoplast envelope [Term] id: CCO:C0001366 name: membrane-enclosed lumen namespace: cellular_component def: "The enclosed volume within a sealed membrane or between two sealed membranes." [GOC:add] xref: GO:0031974 is_a: CCO:C0000200 ! cellular_component [Term] id: CCO:C0001367 name: envelope namespace: cellular_component def: "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer, also includes the space between layers." [GOC:mah, GOC:pz] subset: gosubset_prok xref: GO:0031975 is_a: CCO:C0000200 ! cellular_component [Term] id: CCO:C0001368 name: plastid thylakoid namespace: cellular_component def: "Any thylakoid within a plastid." [GOC:pz] xref: GO:0031976 is_a: CCO:C0000689 ! thylakoid is_a: CCO:C0001376 ! organelle subcompartment is_a: CCO:C0001854 ! plastid part [Term] id: CCO:C0001369 name: thylakoid lumen namespace: cellular_component def: "The volume enclosed by a thylakoid membrane." [GOC:mah, GOC:pz] xref: GO:0031977 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001855 ! thylakoid part [Term] id: CCO:C0001370 name: plastid thylakoid lumen namespace: cellular_component def: "The volume enclosed by a plastid thylakoid membrane." [GOC:mah] xref: GO:0031978 is_a: CCO:C0001369 ! thylakoid lumen is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0001368 ! plastid thylakoid [Term] id: CCO:C0001371 name: plasma membrane-derived thylakoid lumen namespace: cellular_component def: "The volume enclosed by a plasma membrane-derived thylakoid." [GOC:mah, GOC:mtg_sensu] synonym: "plasma membrane thylakoid lumen" EXACT [] synonym: "thylakoid lumen (sensu Cyanobacteria)" EXACT [] xref: GO:0031979 is_a: CCO:C0001369 ! thylakoid lumen is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0000942 ! plasma membrane-derived thylakoid [Term] id: CCO:C0001372 name: mitochondrial lumen namespace: cellular_component def: "The volume enclosed by the mitochondrial inner membrane." [GOC:mah, GOC:pz] xref: GO:0031980 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001848 ! mitochondrial part [Term] id: CCO:C0001373 name: nuclear lumen namespace: cellular_component def: "The volume enclosed by the nuclear inner membrane." [GOC:mah, GOC:pz] xref: GO:0031981 is_a: CCO:C0001749 ! organelle lumen is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001374 name: vesicle namespace: cellular_component def: "Any small, fluid-filled, spherical organelle enclosed by membrane or protein." [GOC:mah, GOC:pz] subset: goslim_pir subset: gosubset_prok xref: GO:0031982 is_a: CCO:C0001742 ! organelle relationship: location_of CCO:B0054765 ! GNAS3_HUMAN relationship: location_of CCO:B0058795 ! NOD2_HUMAN relationship: location_of CCO:B0059029 ! VAPA_HUMAN relationship: location_of CCO:B0062887 ! CETP_HUMAN [Term] id: CCO:C0001375 name: vesicle lumen namespace: cellular_component def: "The volume enclosed by the membrane or protein that forms a vesicle." [GOC:mah] xref: GO:0031983 is_a: CCO:C0001749 ! organelle lumen relationship: part_of CCO:C0002125 ! membrane-bounded vesicle [Term] id: CCO:C0001376 name: organelle subcompartment namespace: cellular_component def: "A compartment that is completely or partially membrane-enclosed, and is part of an organelle." [GOC:mah, GOC:pz] synonym: "suborganelle compartment" EXACT [] xref: GO:0031984 is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0002127 ! membrane-bounded organelle [Term] id: CCO:C0001377 name: Golgi cisterna namespace: cellular_component def: "Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex." [GOC:mah] xref: GO:0031985 is_a: CCO:C0001376 ! organelle subcompartment is_a: CCO:C0001850 ! Golgi apparatus part relationship: part_of CCO:C0000376 ! Golgi stack [Term] id: CCO:C0001378 name: proteinoplast namespace: cellular_component def: "A leucoplast in which protein is stored." [GOC:pz] xref: GO:0031986 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0001380 name: interleukin-28 receptor complex namespace: cellular_component def: "A protein complex that binds interleukin-28 and interleukin-29. Composed of two subunits, IL-28R alpha and IL-10R beta." [GOC:rh2] xref: GO:0032002 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0057317 ! IL29_HUMAN relationship: location_of CCO:B0057318 ! I28RA_HUMAN relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001381 name: early phagosome namespace: cellular_component def: "A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis." [GOC:mah, PMID:12388753] synonym: "early phagocytic vesicle" EXACT [] xref: GO:0032009 is_a: CCO:C0001950 ! phagocytic vesicle [Term] id: CCO:C0001382 name: phagolysosome namespace: cellular_component def: "A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes." [GOC:mah, PMID:12388753] synonym: "late phagocytic vesicle" RELATED [] synonym: "late phagosome" RELATED [] xref: GO:0032010 is_a: CCO:C0000350 ! secondary lysosome is_a: CCO:C0001950 ! phagocytic vesicle [Term] id: CCO:C0001383 name: mitochondrial cloud namespace: cellular_component def: "A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material." [PMID:6541166] synonym: "Balbiani body" EXACT [] xref: GO:0032019 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle [Term] id: CCO:C0001384 name: NELF complex namespace: cellular_component def: "A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing." [PMID:12612062] synonym: "negative elongation factor complex" EXACT [] xref: GO:0032021 is_a: CCO:C0000523 ! transcription elongation factor complex [Term] id: CCO:C0001385 name: integrator complex namespace: cellular_component def: "A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II." [PMID:16239144] xref: GO:0032039 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0005586 ! DSS1_HUMAN relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0001387 name: DSIF complex namespace: cellular_component def: "A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions." [PMID:12242279, PMID:12653964, PMID:12676794, PMID:16581788] synonym: "5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex" EXACT [] synonym: "DRB sensitivity inducing factor complex" EXACT [] synonym: "Spt4-Spt5 complex" EXACT [] xref: GO:0032044 is_a: CCO:C0000523 ! transcription elongation factor complex [Term] id: CCO:C0001388 name: guanyl-nucleotide exchange factor complex namespace: cellular_component def: "A protein complex that stimulates the exchange of guanyl nucleotides by a GTPase." [GOC:mah] xref: GO:0032045 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001389 name: micropexophagy-specific membrane apparatus namespace: cellular_component def: "A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole." [PMID:15563611] synonym: "micropexophagic apparatus" EXACT [] synonym: "MIPA" EXACT [] xref: GO:0032046 is_a: CCO:C0001376 ! organelle subcompartment is_a: CCO:C0001856 ! vacuolar part [Term] id: CCO:C0001390 name: mitosome namespace: cellular_component def: "A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria." [PMID:10361303, PMID:14614504] synonym: "crypton" EXACT [] xref: GO:0032047 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0001391 name: bleb namespace: cellular_component def: "A cell extension characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusions." [PMID:12083798, PMID:16624291] subset: goslim_pir xref: GO:0032059 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0069016 ! P2RX7_HUMAN-Phosphotyrosine343 [Term] id: CCO:C0001392 name: Type IV site-specific deoxyribonuclease complex namespace: cellular_component def: "A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation." [PMID:12654995] synonym: "Type IV restriction enzyme complex" EXACT [] xref: GO:0032068 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001393 name: cohesin loading complex namespace: cellular_component def: "A complex required for the loading of cohesin onto DNA prior to the establishment of cohesion. Appears to be eukaryotically conserved." [GOC:vw, PMID:10882066] xref: GO:0032116 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001394 name: horsetail-astral microtubule array namespace: cellular_component def: "An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement." [GOC:mah, PMID:16111942] synonym: "HAA" EXACT [] xref: GO:0032117 is_a: CCO:C0000387 ! aster [Term] id: CCO:C0001395 name: deep fiber namespace: cellular_component def: "Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm." [PMID:10503189] synonym: "deep fibre" EXACT [] xref: GO:0032123 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0001350 ! oral apparatus [Term] id: CCO:C0001396 name: eisosome namespace: cellular_component def: "Any of the large immobile protein assemblies at the plasma membrane that mark endocytic sites. In yeast, S. cerevisiae, these structures are primarily composed of Pil1p and Lsp1p." [PMID:16496001] xref: GO:0032126 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001867 ! cell cortex part [Term] id: CCO:C0001397 name: dense core granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a dense core granule." [GOC:mah] xref: GO:0032127 is_a: CCO:C0001031 ! secretory granule membrane relationship: part_of CCO:C0001118 ! dense core granule [Term] id: CCO:C0001398 name: chromosome passenger complex namespace: cellular_component def: "A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger comples coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain containing protein survivin, aurora kinase and INCENP." [GOC:vw, PMID:16824200] xref: GO:0032133 is_a: CCO:C0000435 ! microtubule associated complex [Term] id: CCO:C0001399 name: 4-aminobutyrate transaminase complex namespace: cellular_component def: "A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity." [GOC:mah, PMID:15528998] synonym: "ABAT complex" EXACT [] synonym: "GABA transaminase complex" EXACT [] synonym: "GABA-T complex" EXACT [] xref: GO:0032144 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001400 name: mitotic septin complex namespace: cellular_component def: "A heterooligomeric septin complex that acts during mitotic cell division." [GOC:krc, PMID:16009555] xref: GO:0032151 is_a: CCO:C0001135 ! septin complex [Term] id: CCO:C0001401 name: meiotic septin complex namespace: cellular_component def: "A heterooligomeric septin complex that acts during meiotic cell division." [GOC:krc, PMID:16009555] xref: GO:0032152 is_a: CCO:C0001135 ! septin complex [Term] id: CCO:C0001402 name: cell division site namespace: cellular_component def: "The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. The cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane. The mitotic, or meiotic, spindle is aligned perpendicular to the division plane." [GOC:krc, GOC:ns, PMID:12101122, PMID:15380095] subset: goslim_pir synonym: "cell division plane" EXACT [] xref: GO:0032153 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001403 name: cleavage furrow namespace: cellular_component def: "In animal cells, the first sign of cleavage, or cytokinesis, is the appearance of a shallow groove in the cell surface near the old metaphase plate. A contractile ring containing actin and myosin, is located just inside the plasma membrane at the location of the furrow. Ring contraction is associated with centripetal growth of the membrane that deepens the cleavage furrow and divides the cytoplasm of the two daughter cells. While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists." [ISBN:0805319409] xref: GO:0032154 is_a: CCO:C0001404 ! cell division site part relationship: location_of CCO:B0032855 ! MYH10_HUMAN-Phosphothreonine1960 relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 [Term] id: CCO:C0001404 name: cell division site part namespace: cellular_component def: "Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell." [GOC:mah] synonym: "cell division plane part" EXACT [] xref: GO:0032155 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0001402 ! cell division site [Term] id: CCO:C0001405 name: septin cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes." [GOC:mah] xref: GO:0032156 is_a: CCO:C0000421 ! cytoskeleton [Term] id: CCO:C0001406 name: prospore contractile ring namespace: cellular_component def: "A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis." [GOC:krc, PMID:16009555] synonym: "actomyosin ring (sensu Saccharomyces)" BROAD [] synonym: "cytokinetic ring (sensu Saccharomyces)" BROAD [] synonym: "meiotic contractile ring" RELATED [] xref: GO:0032157 is_a: CCO:C0000394 ! contractile ring relationship: part_of CCO:C0002135 ! ascospore-type prospore [Term] id: CCO:C0001407 name: septin band namespace: cellular_component def: "A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously." [GOC:krc, PMID:16151244] xref: GO:0032158 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0001405 ! septin cytoskeleton [Term] id: CCO:C0001408 name: septin cap namespace: cellular_component def: "A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentiously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244] xref: GO:0032159 is_a: CCO:C0001405 ! septin cytoskeleton is_a: CCO:C0001849 ! cytoskeletal part [Term] id: CCO:C0001409 name: septin filament array namespace: cellular_component def: "Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans." [GOC:krc, PMID:16151244] synonym: "septin bar" RELATED [] xref: GO:0032160 is_a: CCO:C0001405 ! septin cytoskeleton is_a: CCO:C0001849 ! cytoskeletal part [Term] id: CCO:C0001410 name: cleavage apparatus septin structure namespace: cellular_component def: "Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis." [GOC:krc, PMID:12101122, PMID:15774761, PMID:16009555] xref: GO:0032161 is_a: CCO:C0001404 ! cell division site part is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0000489 ! cell cortex relationship: part_of CCO:C0001405 ! septin cytoskeleton [Term] id: CCO:C0001411 name: mating projection septin band namespace: cellular_component def: "A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection)." [GOC:krc, GOC:mah, PMID:16151244] xref: GO:0032162 is_a: CCO:C0001407 ! septin band [Term] id: CCO:C0001412 name: hyphal septin band namespace: cellular_component def: "A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously." [GOC:16151244, GOC:krc, GOC:mah] xref: GO:0032163 is_a: CCO:C0001407 ! septin band [Term] id: CCO:C0001413 name: hyphal septin cap namespace: cellular_component def: "A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentiously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244] xref: GO:0032164 is_a: CCO:C0001408 ! septin cap [Term] id: CCO:C0001414 name: prospore septin filament array namespace: cellular_component def: "Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation." [GOC:krc, PMID:16151244] xref: GO:0032165 is_a: CCO:C0001409 ! septin filament array [Term] id: CCO:C0001415 name: chlamydospore septin filament array namespace: cellular_component def: "Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation." [GOC:krc, PMID:16151244] xref: GO:0032166 is_a: CCO:C0001409 ! septin filament array [Term] id: CCO:C0001416 name: hyphal septin ring namespace: cellular_component def: "A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244] xref: GO:0032168 is_a: CCO:C0000490 ! septin ring [Term] id: CCO:C0001417 name: prospore septin ring namespace: cellular_component def: "A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244] xref: GO:0032169 is_a: CCO:C0000490 ! septin ring is_a: CCO:C0001410 ! cleavage apparatus septin structure relationship: part_of CCO:C0002135 ! ascospore-type prospore [Term] id: CCO:C0001418 name: pseudohyphal septin ring namespace: cellular_component def: "A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins." [GOC:krc, GOC:mah, PMID:16151244] xref: GO:0032170 is_a: CCO:C0000490 ! septin ring [Term] id: CCO:C0001419 name: germ tube septin cap namespace: cellular_component def: "A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentiously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol." [GOC:krc, PMID:16151244] xref: GO:0032171 is_a: CCO:C0001408 ! septin cap [Term] id: CCO:C0001420 name: germ tube septin ring namespace: cellular_component def: "A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins." [GOC:krc, PMID:16151244] xref: GO:0032172 is_a: CCO:C0000490 ! septin ring relationship: part_of CCO:C0001427 ! germ tube [Term] id: CCO:C0001421 name: septin collar namespace: cellular_component def: "A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell." [GOC:krc, PMID:16009555, PMID:16151244] xref: GO:0032173 is_a: CCO:C0001405 ! septin cytoskeleton is_a: CCO:C0001849 ! cytoskeletal part [Term] id: CCO:C0001422 name: cellular bud neck septin collar namespace: cellular_component def: "A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck." [GOC:krc, PMID:16009555] xref: GO:0032174 is_a: CCO:C0000076 ! cellular bud neck septin structure is_a: CCO:C0001410 ! cleavage apparatus septin structure is_a: CCO:C0001421 ! septin collar [Term] id: CCO:C0001423 name: mating projection septin ring namespace: cellular_component def: "A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip." [GOC:krc, GOC:mah, PMID:16151244] xref: GO:0032175 is_a: CCO:C0000490 ! septin ring [Term] id: CCO:C0001424 name: split septin rings namespace: cellular_component def: "A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well." [GOC:krc, PMID:16009555, PMID:16151244] xref: GO:0032176 is_a: CCO:C0001405 ! septin cytoskeleton is_a: CCO:C0001849 ! cytoskeletal part [Term] id: CCO:C0001425 name: cellular bud neck split septin rings namespace: cellular_component def: "Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated." [GOC:krc, PMID:16009555] xref: GO:0032177 is_a: CCO:C0000076 ! cellular bud neck septin structure is_a: CCO:C0001410 ! cleavage apparatus septin structure is_a: CCO:C0001424 ! split septin rings [Term] id: CCO:C0001426 name: medial membrane band namespace: cellular_component def: "A sterol rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum." [PMID:15517003] synonym: "sterol-rich membrane band" RELATED [] xref: GO:0032178 is_a: CCO:C0001404 ! cell division site part [Term] id: CCO:C0001427 name: germ tube namespace: cellular_component def: "The slender tubular outgrowth first produced by most spores in germination." [ISBN:0877799148] subset: goslim_pir xref: GO:0032179 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001428 name: post-lysosomal vacuole namespace: cellular_component def: "A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis." [GOC:pf, PMID:9276759, PMID:9394012] xref: GO:0032195 is_a: CCO:C0000355 ! vacuole is_a: CCO:C0000983 ! endocytic vesicle [Term] id: CCO:C0001429 name: Clr6 histone deacetylase complex II' namespace: cellular_component def: "A eukaryotically conserved histone deacetylse complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; homologs thereof in other species)." [GOC:vw, PMID:12773392, PMID:17450151] xref: GO:0032221 is_a: CCO:C0000008 ! histone deacetylase complex [Term] id: CCO:C0001430 name: asymmetric synapse namespace: cellular_component def: "A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density." [GOC:dgh, GOC:ef] xref: GO:0032279 is_a: CCO:C0001900 ! synapse relationship: location_of CCO:B0055310 ! ACHA7_HUMAN [Term] id: CCO:C0001431 name: symmetric synapse namespace: cellular_component def: "A type of synapse occurring primarily on dendrite shafts and neuronal cell bodies. Symmetric synapses involve axons containing clusters of predominantly flattened or elongated vesicles and do not contain a prominent postsynaptic density." [GOC:dgh, GOC:ef] xref: GO:0032280 is_a: CCO:C0001900 ! synapse [Term] id: CCO:C0001432 name: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex namespace: cellular_component def: "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus." [GOC:ef] synonym: "AMPA receptor " RELATED [] synonym: "AMPA-selective glutamate receptor complex" EXACT [] xref: GO:0032281 is_a: CCO:C0000545 ! ionotropic glutamate receptor complex [Term] id: CCO:C0001433 name: plastid acetyl-CoA carboxylase complex namespace: cellular_component def: "An acetyl-CoA carboxylase complex located in the stroma of a plastid." [GOC:mah] synonym: "plastid ACCase complex" EXACT [] xref: GO:0032282 is_a: CCO:C0000565 ! acetyl-CoA carboxylase complex is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000660 ! plastid stroma [Term] id: CCO:C0001434 name: plastid acetate CoA-transferase complex namespace: cellular_component def: "An acetate CoA-transferase complex located in the stroma of a plastid." [GOC:mah] xref: GO:0032283 is_a: CCO:C0000577 ! acetate CoA-transferase complex relationship: part_of CCO:C0001433 ! plastid acetyl-CoA carboxylase complex [Term] id: CCO:C0001435 name: plastid biotin carboxylase complex namespace: cellular_component def: "A biotin carboxylase complex located in the stroma of a plastid." [GOC:mah] xref: GO:0032284 is_a: CCO:C0000590 ! biotin carboxylase complex relationship: part_of CCO:C0001433 ! plastid acetyl-CoA carboxylase complex [Term] id: CCO:C0001436 name: ribonuclease H2 complex namespace: cellular_component def: "A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p." [GOC:mah, PMID:14734815] synonym: "RNase H2 complex" EXACT [] xref: GO:0032299 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001437 name: mismatch repair complex namespace: cellular_component def: "Any complex formed of proteins that act in mismatch repair." [GOC:mah] subset: goslim_pir xref: GO:0032300 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001438 name: MutSalpha complex namespace: cellular_component def: "A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6." [PMID:11005803] synonym: "MMR complex" BROAD [] synonym: "MSH2/MSH6 complex" EXACT [] xref: GO:0032301 is_a: CCO:C0001437 ! mismatch repair complex relationship: location_of CCO:B0013014 ! MSH2_HUMAN-Phosphoserine860 relationship: location_of CCO:B0013022 ! MSH6_HUMAN-Phosphoserine227 relationship: location_of CCO:B0023202 ! Q53FK0_HUMAN [Term] id: CCO:C0001439 name: MutSbeta complex namespace: cellular_component def: "A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3." [PMID:11005803] synonym: "MMR complex" BROAD [] synonym: "MSH2/MSH3 complex" EXACT [] xref: GO:0032302 is_a: CCO:C0001437 ! mismatch repair complex relationship: location_of CCO:B0013014 ! MSH2_HUMAN-Phosphoserine860 relationship: location_of CCO:B0023202 ! Q53FK0_HUMAN relationship: location_of CCO:B0048331 ! MSH3_HUMAN-Phosphotyrosine1068 [Term] id: CCO:C0001440 name: angiogenin-PRI complex namespace: cellular_component def: "A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis." [PMID:2706246, PMID:3470787] synonym: "angiogenin-placental ribonuclease inhibitor complex" EXACT [] xref: GO:0032311 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 [Term] id: CCO:C0001441 name: MutLalpha complex namespace: cellular_component def: "A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2." [GOC:vk] synonym: "MLH1/PMS2 complex" EXACT [] synonym: "MMR complex" BROAD [] xref: GO:0032389 is_a: CCO:C0001437 ! mismatch repair complex relationship: location_of CCO:B0014698 ! WRN_HUMAN-Phosphoserine1141 [Term] id: CCO:C0001442 name: MutLbeta complex namespace: cellular_component def: "A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1." [GOC:vk] synonym: "MLH1/PMS1 complex" EXACT [] synonym: "MMR complex" BROAD [] xref: GO:0032390 is_a: CCO:C0001437 ! mismatch repair complex [Term] id: CCO:C0001443 name: photoreceptor connecting cilium namespace: cellular_component def: "A 9+0 cilium that forms the portion of the axoneme traversing the boundary between the photoreceptor inner and outer segments." [PMID:15917207, PMID:8718680] synonym: "photoreceptor cilium" RELATED [] xref: GO:0032391 is_a: CCO:C0001281 ! nonmotile primary cilium relationship: location_of CCO:B0067135 ! IQCB1_HUMAN-Phosphoserine572 [Term] id: CCO:C0001444 name: MHC class Ib protein complex namespace: cellular_component def: "A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15928678] xref: GO:0032398 is_a: CCO:C0001668 ! MHC protein complex [Term] id: CCO:C0001445 name: extrinsic to lysosome membrane namespace: cellular_component def: "Loosely bound to one surface of the lysosome membrane, but not integrated into the hydrophobic region." [GOC:mah] synonym: "extrinsic to lysosomal membrane" EXACT [] xref: GO:0032419 is_a: CCO:C0000052 ! extrinsic to vacuolar membrane relationship: part_of CCO:C0000348 ! lysosomal membrane [Term] id: CCO:C0001446 name: stereocilium namespace: cellular_component def: "An actin-based protrusion from the apical surface of auditory and vestibular hair cells. Bundles of stereocilia act as mechanosensory organelles." [GOC:ecd, PMID:15661519, PMID:7840137] xref: GO:0032420 is_a: CCO:C0000459 ! microvillus relationship: location_of CCO:B0002265 ! USH1C_HUMAN relationship: part_of CCO:C0001447 ! stereocilium bundle [Term] id: CCO:C0001447 name: stereocilium bundle namespace: cellular_component def: "An actin-based, cross-linked cellular protrusion on the apical surface of auditory and vestibular hair cells. Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes." [GOC:ecd, PMID:15661519, PMID:7840137] subset: goslim_pir synonym: "stereocilia bundle" EXACT [] xref: GO:0032421 is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle [Term] id: CCO:C0001448 name: stereocilium bundle tip namespace: cellular_component def: "The end of a stereocilium bundle, distal to the site of the bundle's attachment to the apical cell surface." [GOC:ecd, PMID:17021180] synonym: "stereocilium tip" RELATED [] xref: GO:0032426 is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0001447 ! stereocilium bundle [Term] id: CCO:C0001449 name: actin filament bundle namespace: cellular_component def: "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah] xref: GO:0032432 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0001450 name: filopodium tip namespace: cellular_component def: "The end of a filopodium distal to the body of the cell." [GOC:mah] xref: GO:0032433 is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0000989 ! filopodium [Term] id: CCO:C0001451 name: cuticular plate namespace: cellular_component def: "A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted." [PMID:12485990, PMID:2592408, PMID:8071151] xref: GO:0032437 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0001056 ! cortical actin cytoskeleton [Term] id: CCO:C0001452 name: activin responsive factor complex namespace: cellular_component def: "A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor." [PMID:12374795, PMID:9288972] comment: Note that this term should not be confused with any of the molecular function and biological process terms that refer to the small GTPase ARF (ADP-ribosylation factor). synonym: "ARF complex" EXACT [] xref: GO:0032444 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0054655 ! FOXH1_HUMAN [Term] id: CCO:C0001453 name: CBM complex namespace: cellular_component def: "A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation." [PMID:12909454] synonym: "CARMA1-BCL10-Malt1 complex" EXACT [] xref: GO:0032449 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0058537 ! CAR10_HUMAN relationship: location_of CCO:B0059106 ! MALT1_HUMAN [Term] id: CCO:C0001454 name: external side of mitochondrial outer membrane namespace: cellular_component def: "The external (cytoplasmic face) of the mitochondrial outer membrane." [GOC:mah] synonym: "cytosolic side of mitochondrial outer membrane" EXACT [] synonym: "external side of mitochondrial envelope" RELATED [] xref: GO:0032473 is_a: CCO:C0001874 ! mitochondrial membrane part relationship: location_of CCO:B0056531 ! LRRK2_HUMAN [Term] id: CCO:C0001455 name: decaprenyl diphosphate synthase complex namespace: cellular_component def: "A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis." [GOC:mah, PMID:14519123] subset: goslim_pir xref: GO:0032476 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0001456 name: homodimeric decaprenyl diphosphate synthase complex namespace: cellular_component def: "A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis." [PMID:14519123] xref: GO:0032477 is_a: CCO:C0001455 ! decaprenyl diphosphate synthase complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001457 name: heterotetrameric decaprenyl diphosphate synthase complex namespace: cellular_component def: "A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1." [PMID:14519123] xref: GO:0032478 is_a: CCO:C0001455 ! decaprenyl diphosphate synthase complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0001458 name: SOD1-calcineurin complex namespace: cellular_component def: "A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1." [GOC:mah, PMID:17324120] xref: GO:0032517 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001459 name: cortical endoplasmic reticulum namespace: cellular_component def: "A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements." [GOC:se, PMID:10931860, PMID:17686782] synonym: "cortical ER" EXACT [] synonym: "peripheral endoplasmic reticulum" EXACT [] synonym: "peripheral ER" EXACT [] xref: GO:0032541 is_a: CCO:C0001851 ! endoplasmic reticulum part [Term] id: CCO:C0001460 name: CURI complex namespace: cellular_component def: "A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p andIfh1p." [PMID:17452446] xref: GO:0032545 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001461 name: aleurone grain membrane namespace: cellular_component def: "The lipid bilayer surrounding an aleurone grain." [GOC:ecd] xref: GO:0032578 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0001516 ! aleurone grain [Term] id: CCO:C0001462 name: apical lamina of hyaline layer namespace: cellular_component def: "A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms." [GOC:ecd, PMID:2060714, PMID:7608987, PMID:9638331] xref: GO:0032579 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001541 ! hyaline layer [Term] id: CCO:C0001463 name: Golgi cisterna membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex." [GOC:ecd, GOC:mah] synonym: "Golgi stack membrane" EXACT [] xref: GO:0032580 is_a: CCO:C0000021 ! Golgi membrane relationship: part_of CCO:C0001377 ! Golgi cisterna [Term] id: CCO:C0001464 name: growth cone membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a growth cone." [GOC:mah] xref: GO:0032584 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0001006 ! growth cone [Term] id: CCO:C0001465 name: multivesicular body membrane namespace: cellular_component def: "The lipid bilayer surrounding a multivesicular body." [GOC:mah] synonym: "multivesicular endosome membrane" EXACT [] synonym: "MVB membrane" EXACT [] synonym: "MVE membrane" EXACT [] xref: GO:0032585 is_a: CCO:C0001340 ! late endosome membrane relationship: part_of CCO:C0000354 ! multivesicular body [Term] id: CCO:C0001466 name: protein storage vacuole membrane namespace: cellular_component def: "The lipid bilayer surrounding a protein storage vacuole." [GOC:mah] xref: GO:0032586 is_a: CCO:C0002159 ! plant-type vacuole membrane [Term] id: CCO:C0001467 name: ruffle membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a ruffle." [GOC:mah] synonym: "membrane ruffle" RELATED [] xref: GO:0032587 is_a: CCO:C0001173 ! cell projection membrane is_a: CCO:C0001176 ! leading edge membrane relationship: part_of CCO:C0000181 ! ruffle [Term] id: CCO:C0001468 name: trans-Golgi network membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network." [GOC:mah] synonym: "Golgi trans face membrane" RELATED [] synonym: "trans Golgi network membrane" EXACT [] xref: GO:0032588 is_a: CCO:C0000021 ! Golgi membrane relationship: location_of CCO:B0066490 ! GNAS2_HUMAN-Phosphoserine51 relationship: part_of CCO:C0000381 ! trans-Golgi network [Term] id: CCO:C0001469 name: neuron projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a neuron projection." [GOC:mah] xref: GO:0032589 is_a: CCO:C0001173 ! cell projection membrane is_a: CCO:C0001176 ! leading edge membrane relationship: part_of CCO:C0001707 ! neuron projection [Term] id: CCO:C0001470 name: dendrite membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a dendrite." [GOC:mah] xref: GO:0032590 is_a: CCO:C0001469 ! neuron projection membrane [Term] id: CCO:C0001471 name: dendritic spine membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a dendritic spine." [GOC:mah] xref: GO:0032591 is_a: CCO:C0001469 ! neuron projection membrane relationship: part_of CCO:C0001729 ! dendritic spine [Term] id: CCO:C0001472 name: integral to mitochondrial membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the mitochondrial membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:mah] xref: GO:0032592 is_a: CCO:C0001152 ! intrinsic to Golgi membrane is_a: CCO:C0001188 ! integral to organelle membrane [Term] id: CCO:C0001473 name: insulin-responsive compartment namespace: cellular_component def: "A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2." [PMID:17644329] synonym: "GLUT4 storage compartment" EXACT [] synonym: "GSC" RELATED [] synonym: "IRC" RELATED [] xref: GO:0032593 is_a: CCO:C0000985 ! secretory granule [Term] id: CCO:C0001474 name: NHE3/E3KARP/ACTN4 complex namespace: cellular_component def: "A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments." [PMID:11948184] synonym: " NHE3/E3KARP/alpha-actinin complex" EXACT [] xref: GO:0032766 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001475 name: Piccolo NuA4 histone acetyltransferase complex namespace: cellular_component def: "A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p." [PMID:12782659, PMID:15964809] xref: GO:0032777 is_a: CCO:C0001724 ! H4/H2A histone acetyltransferase complex [Term] id: CCO:C0001476 name: ELL-EAF complex namespace: cellular_component def: "A heterodimeric protein complex that acts as an RNA polymerase II elongation factor; the complex is conserved from yeast to humans, and is present in S. pombe, but absent from S. cerevisiae." [PMID:17150956] xref: GO:0032783 is_a: CCO:C0000523 ! transcription elongation factor complex [Term] id: CCO:C0001477 name: SMN complex namespace: cellular_component def: "A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus." [PMID:16434402, PMID:17023415] synonym: "survival motor neuron complex" EXACT [] xref: GO:0032797 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001478 name: Swi5-Sfr1 complex namespace: cellular_component def: "A conserved eukaryotic protein complex involved in DNA recombination repair; in Schizosaccharomyces the complex contains two Swi5 monomers and one Sfr1 monomer." [PMID:16921379] synonym: "Swi5 complex" BROAD [] xref: GO:0032798 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001479 name: carboxy-terminal domain protein kinase complex namespace: cellular_component def: "A protein complex that phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats; in Saccharomyces the complex contains Ctk1p, Ctk2p, and Ctk3p." [PMID:15047695, PMID:16721054] synonym: "CTDK complex" EXACT [] synonym: "CTDK-1" NARROW [] xref: GO:0032806 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001480 name: DNA ligase IV complex namespace: cellular_component def: "A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p." [PMID:16314503] xref: GO:0032807 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0064815 ! DNLI4_HUMAN-Phosphothreonine347 relationship: location_of CCO:B0071895 ! XRCC4_HUMAN-Phosphoserine327 [Term] id: CCO:C0001481 name: cell soma membrane namespace: cellular_component def: "The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections." [GOC:ecd] synonym: "cell body membrane" EXACT [] xref: GO:0032809 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0001709 ! cell soma [Term] id: CCO:C0001482 name: cell projection cytoplasm namespace: cellular_component def: "All of the contents of a cell projection, excluding the plasma membrane surrounding the projection." [GOC:mah] xref: GO:0032838 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001881 ! cell projection part [Term] id: CCO:C0001483 name: dendrite cytoplasm namespace: cellular_component def: "All of the contents of a dendrite, excluding the surrounding plasma membrane." [GOC:mah] synonym: "dendritic cytoplasm" EXACT [] xref: GO:0032839 is_a: CCO:C0001482 ! cell projection cytoplasm relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: part_of CCO:C0001005 ! dendrite [Term] id: CCO:C0001484 name: cytochrome bc(1) complex namespace: cellular_component def: "A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species." [PMID:16228398, PMID:16352458, PMID:17200733] synonym: "complex III" EXACT [] synonym: "cytochrome bc1 complex" EXACT [] xref: GO:0032842 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part [Term] id: CCO:C0001485 name: Mdm10/Mdm12/Mmm1 complex namespace: cellular_component def: "A protein complex that links mtDNA and mitochondrial outer and inner membranes to the cytoskeletal system." [PMID:13679517] xref: GO:0032865 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000327 ! mitochondrial outer membrane [Term] id: CCO:C0001486 name: sarcosine oxidase complex namespace: cellular_component def: "A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity." [GOC:mah, GOC:mlg] xref: GO:0032921 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001487 name: SREBP-SCAP complex namespace: cellular_component def: "A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed." [PMID:12923525] synonym: "Sre1-Scp1 complex" EXACT [] xref: GO:0032936 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part [Term] id: CCO:C0001488 name: SREBP-SCAP-Insig complex namespace: cellular_component def: "A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) the ER membrane." [PMID:12923525] xref: GO:0032937 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0000990 ! integral to endoplasmic reticulum membrane [Term] id: CCO:C0001489 name: endosomal scaffold complex namespace: cellular_component def: "A complex in eukaryotic cells containing Mapbpip (p14,Rab25) and Map2k1ip1 (MP1). The complex anchors on late endosomes and is involved in activating ERK 1/2, key components in MAPK signaling." [PMID:15263099] xref: GO:0032969 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001859 ! endosomal part relationship: part_of CCO:C0001340 ! late endosome membrane [Term] id: CCO:C0001490 name: myosin filament namespace: cellular_component def: "A protein complex containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament." [GOC:mah] synonym: "myosin thick filament" RELATED [] synonym: "thick filament" RELATED [] xref: GO:0032982 is_a: CCO:C0000788 ! myosin complex [Term] id: CCO:C0001491 name: kainate selective glutamate receptor complex namespace: cellular_component def: "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluR5-7 and KA-1/2 subunits." [http://www.bris.ac.uk/Depts/Synaptic/info/glutamate.html] xref: GO:0032983 is_a: CCO:C0000545 ! ionotropic glutamate receptor complex [Term] id: CCO:C0001492 name: macromolecular complex namespace: cellular_component def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together." [GOC:mah] subset: goslim_pir subset: gosubset_prok synonym: "macromolecule complex" EXACT [] xref: GO:0032991 is_a: CCO:C0000200 ! cellular_component [Term] id: CCO:C0001493 name: protein-carbohydrate complex namespace: cellular_component def: "A macromolecular complex containing both protein and carbohydrate molecules." [GOC:mah] subset: gosubset_prok xref: GO:0032992 is_a: CCO:C0001492 ! macromolecular complex [Term] id: CCO:C0001494 name: protein-DNA complex namespace: cellular_component def: "A macromolecular complex containing both protein and DNA molecules." [GOC:mah] subset: gosubset_prok xref: GO:0032993 is_a: CCO:C0001492 ! macromolecular complex [Term] id: CCO:C0001495 name: protein-lipid complex namespace: cellular_component def: "A macromolecular complex containing both protein and lipid molecules." [GOC:mah] subset: gosubset_prok xref: GO:0032994 is_a: CCO:C0001492 ! macromolecular complex [Term] id: CCO:C0001496 name: Bcl3-Bcl10 complex namespace: cellular_component def: "A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus." [PMID:16280327] xref: GO:0032996 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0041126 ! BCL3_HUMAN-Phosphoserine394 [Term] id: CCO:C0001497 name: Fc receptor complex namespace: cellular_component def: "A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] subset: goslim_pir synonym: "FcR complex" EXACT [] synonym: "immunoglobulin receptor complex" BROAD [] xref: GO:0032997 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001498 name: Fc-epsilon receptor I complex namespace: cellular_component def: "A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "FceRI complex" EXACT [] synonym: "IgE receptor complex" BROAD [] synonym: "immunoglobulin E receptor complex" BROAD [] xref: GO:0032998 is_a: CCO:C0001497 ! Fc receptor complex relationship: location_of CCO:B0034788 ! FCERB_HUMAN-Phosphotyrosine229 relationship: location_of CCO:B0066149 ! FCERG_HUMAN-Phosphotyrosine76 [Term] id: CCO:C0001499 name: Fc-alpha receptor I complex namespace: cellular_component def: "A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:12524384] synonym: "FcaRI complex" EXACT [] synonym: "IgA receptor complex" BROAD [] synonym: "immunoglobulin A receptor complex" BROAD [] xref: GO:0032999 is_a: CCO:C0001497 ! Fc receptor complex [Term] id: CCO:C0001500 name: Fc-gamma receptor I complex namespace: cellular_component def: "A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:11244038, PMID:12413532] synonym: "FcgRI complex" EXACT [] synonym: "IgG receptor complex" BROAD [] synonym: "immunoglobulin G receptor complex" BROAD [] xref: GO:0033000 is_a: CCO:C0001497 ! Fc receptor complex [Term] id: CCO:C0001501 name: Fc-gamma receptor III complex namespace: cellular_component def: "A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:11244038, PMID:12413532] synonym: "FcgRIII complex" EXACT [] synonym: "IgG receptor complex" BROAD [] synonym: "immunoglobulin G receptor complex" BROAD [] xref: GO:0033001 is_a: CCO:C0001497 ! Fc receptor complex [Term] id: CCO:C0001502 name: nucleomorph namespace: cellular_component def: "A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively." [PMID:16760254] xref: GO:0033009 is_a: CCO:C0001854 ! plastid part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0001503 name: paranodal junction namespace: cellular_component def: "A highly specialized junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath." [PMID:11395001, PMID:14630217] xref: GO:0033010 is_a: CCO:C0000463 ! intercellular junction [Term] id: CCO:C0001504 name: perinuclear theca namespace: cellular_component def: "A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins." [PMID:17289678, PMID:8025156] xref: GO:0033011 is_a: CCO:C0000421 ! cytoskeleton relationship: location_of CCO:B0001907 ! WBP2L_HUMAN relationship: part_of CCO:C0001996 ! perinuclear region of cytoplasm [Term] id: CCO:C0001505 name: porosome namespace: cellular_component def: "A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles." [PMID:15090256, PMID:16563225] xref: GO:0033012 is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001506 name: rhoptry membrane namespace: cellular_component def: "The lipid bilayer surrounding a rhoptry." [GOC:mah] xref: GO:0033016 is_a: CCO:C0001127 ! organelle membrane relationship: part_of CCO:C0000910 ! rhoptry [Term] id: CCO:C0001507 name: sarcoplasmic reticulum membrane namespace: cellular_component def: "The lipid bilayer surrounding the sarcoplasmic reticulum." [GOC:rph] xref: GO:0033017 is_a: CCO:C0000370 ! endoplasmic reticulum membrane relationship: location_of CCO:B0010641 ! AT2A2_HUMAN-Phosphothreonine537 relationship: location_of CCO:B0063203 ! AT2A3_HUMAN relationship: location_of CCO:B0067224 ! JPH1_HUMAN-Phosphoserine220 relationship: part_of CCO:C0000802 ! sarcoplasmic reticulum [Term] id: CCO:C0001508 name: sarcoplasmic reticulum lumen namespace: cellular_component def: "The volume enclosed by the membranes of the sarcoplasmic reticulum." [GOC:rph] xref: GO:0033018 is_a: CCO:C0000369 ! endoplasmic reticulum lumen relationship: part_of CCO:C0000802 ! sarcoplasmic reticulum [Term] id: CCO:C0001509 name: DNA recombinase mediator complex namespace: cellular_component def: "A protein complex containing two or more Rad51 paralogs and promotes nucleoprotein filament formation during homologous recombination." [GOC:elh, GOC:mah, GOC:vw] subset: goslim_pir xref: GO:0033061 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001510 name: Rhp55-Rhp57 complex namespace: cellular_component def: "A conserved heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces)." [GOC:mah, GOC:vw] synonym: "Rad55-Rad57 complex" EXACT [] xref: GO:0033062 is_a: CCO:C0001509 ! DNA recombinase mediator complex [Term] id: CCO:C0001511 name: Rad51B-Rad51C-Rad51D-XRCC2 complex namespace: cellular_component def: "A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof." [GOC:mah, PMID:16093548, PMID:17114795] synonym: "BCDX2 complex" EXACT [] xref: GO:0033063 is_a: CCO:C0001509 ! DNA recombinase mediator complex [Term] id: CCO:C0001512 name: XRCC2-RAD51D complex namespace: cellular_component def: "A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast." [GOC:mah, GOC:vw, PMID:16093548] synonym: "DX2 complex" EXACT [] xref: GO:0033064 is_a: CCO:C0001509 ! DNA recombinase mediator complex [Term] id: CCO:C0001513 name: Rad51C-XRCC3 complex namespace: cellular_component def: "A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof." [GOC:mah, PMID:16093548, PMID:17114795] synonym: "CX3 complex" EXACT [] xref: GO:0033065 is_a: CCO:C0001509 ! DNA recombinase mediator complex [Term] id: CCO:C0001514 name: Rad51B-Rad51C complex namespace: cellular_component def: "A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof." [GOC:mah, PMID:16093548, PMID:17114795] synonym: "BC complex" EXACT [] xref: GO:0033066 is_a: CCO:C0001509 ! DNA recombinase mediator complex [Term] id: CCO:C0001515 name: Weibel-Palade body namespace: cellular_component def: "A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses." [PMID:11935287, PMID:16087708] xref: GO:0033093 is_a: CCO:C0000981 ! clathrin-coated vesicle is_a: CCO:C0000985 ! secretory granule relationship: location_of CCO:B0031878 ! VWF_HUMAN [Term] id: CCO:C0001516 name: aleurone grain namespace: cellular_component def: "A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes." [http://ejournal.sinica.edu.tw/bbas/content/2004/1/bot451-08.pdf, http://www.springerlink.com/content/q7183h5vr7358278/] synonym: "aleurone body" EXACT [] xref: GO:0033095 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0001517 name: amyloplast envelope namespace: cellular_component def: "The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:mah] xref: GO:0033096 is_a: CCO:C0000654 ! plastid envelope relationship: part_of CCO:C0000630 ! amyloplast [Term] id: CCO:C0001518 name: amyloplast membrane namespace: cellular_component def: "Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope." [GOC:ecd] xref: GO:0033097 is_a: CCO:C0001634 ! plastid membrane relationship: part_of CCO:C0001517 ! amyloplast envelope [Term] id: CCO:C0001519 name: amyloplast inner membrane namespace: cellular_component def: "The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma." [GOC:ecd] xref: GO:0033098 is_a: CCO:C0000656 ! plastid inner membrane is_a: CCO:C0001518 ! amyloplast membrane [Term] id: CCO:C0001520 name: attachment organelle namespace: cellular_component def: "A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division." [http://authors.library.caltech.edu/3529/, PMID:11325545, PMID:12003948] subset: goslim_pir xref: GO:0033099 is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0001521 name: NuA3 histone acetyltransferase complex namespace: cellular_component def: "A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p." [PMID:10817755, PMID:17157260] xref: GO:0033100 is_a: CCO:C0000011 ! histone acetyltransferase complex [Term] id: CCO:C0001522 name: cellular bud membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a cellular bud." [GOC:mah] synonym: "cellular bud plasma membrane" EXACT [] xref: GO:0033101 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000485 ! cellular bud [Term] id: CCO:C0001523 name: acidocalcisome membrane namespace: cellular_component def: "The lipid bilayer surrounding an acidocalcisome." [GOC:ecd, PMID:11378195] xref: GO:0033102 is_a: CCO:C0001127 ! organelle membrane relationship: part_of CCO:C0000919 ! acidocalcisome [Term] id: CCO:C0001524 name: type VI protein secretion system complex namespace: cellular_component def: "A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence." [GOC:mlg, PMID:16432199, PMID:16763151] subset: gosubset_prok synonym: "T6SS complex" EXACT [] xref: GO:0033104 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001525 name: chlorosome envelope namespace: cellular_component def: "The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome." [PMID:14507718, PMID:14729689, PMID:17303128] comment: Note that the chlorosome envelope is not a single or double lipid bilayer, so this term is not a child of 'organelle membrane ; GO:0031090' or 'organelle envelope ; GO:0031967'. synonym: "chlorosome membrane" EXACT [] xref: GO:0033105 is_a: CCO:C0002199 ! organelle-enclosing lipid monolayer relationship: part_of CCO:C0001972 ! chlorosome [Term] id: CCO:C0001526 name: cis-Golgi network membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network." [GOC:mah] synonym: "cis Golgi network membrane" EXACT [] synonym: "Golgi cis face membrane" RELATED [] xref: GO:0033106 is_a: CCO:C0000021 ! Golgi membrane relationship: part_of CCO:C0000380 ! cis-Golgi network [Term] id: CCO:C0001527 name: CVT vesicle namespace: cellular_component def: "A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p)." [GOC:rb, PMID:15138258] xref: GO:0033107 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0001528 name: CVT vesicle membrane namespace: cellular_component def: "The double lipid bilayer surrounding a CVT vesicle." [GOC:ecd] xref: GO:0033110 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0001527 ! CVT vesicle [Term] id: CCO:C0001529 name: attachment organelle membrane namespace: cellular_component def: "The lipid bilayer surrounding an attachment organelle." [GOC:ecd] xref: GO:0033111 is_a: CCO:C0001127 ! organelle membrane relationship: part_of CCO:C0001520 ! attachment organelle [Term] id: CCO:C0001530 name: cyanelle envelope namespace: cellular_component def: "The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:mah] xref: GO:0033112 is_a: CCO:C0000654 ! plastid envelope relationship: part_of CCO:C0000700 ! cyanelle [Term] id: CCO:C0001531 name: cyanelle membrane namespace: cellular_component def: "Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope." [GOC:ecd] xref: GO:0033113 is_a: CCO:C0001634 ! plastid membrane relationship: part_of CCO:C0001530 ! cyanelle envelope [Term] id: CCO:C0001532 name: cyanelle thylakoid lumen namespace: cellular_component def: "The volume enclosed by a cyanelle thylakoid membrane." [GOC:mah] xref: GO:0033114 is_a: CCO:C0001370 ! plastid thylakoid lumen relationship: part_of CCO:C0000701 ! cyanelle thylakoid [Term] id: CCO:C0001533 name: cyanelle thylakoid membrane namespace: cellular_component def: "The lipid bilayer membrane of any thylakoid within a cyanelle." [GOC:mah] xref: GO:0033115 is_a: CCO:C0000701 ! cyanelle thylakoid relationship: part_of CCO:C0002020 ! plastid thylakoid membrane [Term] id: CCO:C0001534 name: ER-Golgi intermediate compartment membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the compartments of the ER-Golgi intermediate compartment system." [GOC:mah, PMID:16723730] xref: GO:0033116 is_a: CCO:C0001127 ! organelle membrane relationship: location_of CCO:B0005676 ! BAP31_HUMAN relationship: location_of CCO:B0006164 ! STX5_HUMAN relationship: location_of CCO:B0055602 ! RAB2A_HUMAN relationship: location_of CCO:B0059091 ! CLN8_HUMAN relationship: location_of CCO:B0064367 ! CKAP4_HUMAN-Phosphoserine312 relationship: part_of CCO:C0000374 ! ER-Golgi intermediate compartment [Term] id: CCO:C0001535 name: esterosome namespace: cellular_component def: "A vesicle filled with crystalline protein that shows sequence similarities with various esterases." [GOC:ecd, PMID:2307702] xref: GO:0033117 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0001536 name: esterosome membrane namespace: cellular_component def: "The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes." [GOC:ecd, PMID:2307702] xref: GO:0033118 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0001535 ! esterosome [Term] id: CCO:C0001537 name: cytoskeletal calyx namespace: cellular_component def: "A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins." [PMID:12243744, PMID:9184090] xref: GO:0033150 is_a: CCO:C0001849 ! cytoskeletal part relationship: part_of CCO:C0001504 ! perinuclear theca [Term] id: CCO:C0001538 name: melanosome membrane namespace: cellular_component def: "The lipid bilayer surrounding a melanosome." [GOC:mah] xref: GO:0033162 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane relationship: part_of CCO:C0001642 ! melanosome relationship: part_of CCO:C0001883 ! chitosome [Term] id: CCO:C0001539 name: microneme membrane namespace: cellular_component def: "The lipid bilayer surrounding a microneme." [GOC:mah] xref: GO:0033163 is_a: CCO:C0001127 ! organelle membrane relationship: part_of CCO:C0000911 ! microneme [Term] id: CCO:C0001540 name: interphotoreceptor matrix namespace: cellular_component def: "A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance." [http://www.glycoforum.gr.jp/science/hyaluronan/HA17/HA17E.html, PMID:1862095, PMID:2194288] xref: GO:0033165 is_a: CCO:C0000203 ! proteinaceous extracellular matrix [Term] id: CCO:C0001541 name: hyaline layer namespace: cellular_component def: "A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms." [http://worms.zoology.wisc.edu/urchins/SUgast_ECM3.html, PMID:1721506, PMID:9473317] xref: GO:0033166 is_a: CCO:C0000203 ! proteinaceous extracellular matrix [Term] id: CCO:C0001542 name: ARC complex namespace: cellular_component def: "A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA." [GOC:vw, PMID:17310250] synonym: "argonaute siRNA chaperone complex" EXACT [] xref: GO:0033167 is_a: CCO:C0001205 ! RNAi effector complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001543 name: gas vesicle shell namespace: cellular_component def: "The proteinaceous structure surrounding a gas vesicle." [GOC:ecd] synonym: "gas vesicle membrane" RELATED [] synonym: "gas vesicle wall" EXACT [] xref: GO:0033172 is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0001236 ! gas vesicle [Term] id: CCO:C0001544 name: chloroplast proton-transporting ATP synthase complex, catalytic core CF(1) namespace: cellular_component def: "The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the choroplast thylakoid membrane when the entire ATP synthase is assembled. The choroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits." [GOC:mah, GOC:pj, PMID:11032839] synonym: "chloroplast proton-transporting F-type ATPase complex, catalytic core CF(1)" EXACT [] xref: GO:0033174 is_a: CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) relationship: part_of CCO:C0001947 ! chloroplast proton-transporting ATP synthase complex [Term] id: CCO:C0001545 name: chloroplast proton-transporting ATP synthase complex, coupling factor CF(o) namespace: cellular_component def: "All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins." [GOC:mah] synonym: "chloroplast proton-transporting ATP synthase complex, coupling factor CF(0)" EXACT [] synonym: "chloroplast proton-transporting F-type ATPase complex, coupling factor CF(o)" EXACT [] xref: GO:0033175 is_a: CCO:C0001924 ! proton-transporting ATP synthase complex, coupling factor F(o) relationship: part_of CCO:C0001947 ! chloroplast proton-transporting ATP synthase complex [Term] id: CCO:C0001546 name: proton-transporting V-type ATPase complex namespace: cellular_component def: "A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane." [GOC:mah, ISBN:0716743663, PMID:16449553] synonym: "hydrogen-translocating V-type ATPase complex" EXACT [] xref: GO:0033176 is_a: CCO:C0000792 ! proton-transporting two-sector ATPase complex [Term] id: CCO:C0001547 name: proton-transporting two-sector ATPase complex, proton-transporting domain namespace: cellular_component def: "A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins." [GOC:mah, PMID:10838056] xref: GO:0033177 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000792 ! proton-transporting two-sector ATPase complex [Term] id: CCO:C0001548 name: proton-transporting two-sector ATPase complex, catalytic domain namespace: cellular_component def: "A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled." [GOC:mah, PMID:10838056] xref: GO:0033178 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000792 ! proton-transporting two-sector ATPase complex [Term] id: CCO:C0001549 name: proton-transporting V-type ATPase, V0 domain namespace: cellular_component def: "A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring." [GOC:mah, ISBN:0716743663, PMID:16449553] xref: GO:0033179 is_a: CCO:C0001547 ! proton-transporting two-sector ATPase complex, proton-transporting domain relationship: part_of CCO:C0001546 ! proton-transporting V-type ATPase complex [Term] id: CCO:C0001550 name: proton-transporting V-type ATPase, V1 domain namespace: cellular_component def: "A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A." [GOC:mah, ISBN:0716743663, PMID:16449553] xref: GO:0033180 is_a: CCO:C0001548 ! proton-transporting two-sector ATPase complex, catalytic domain relationship: part_of CCO:C0001546 ! proton-transporting V-type ATPase complex [Term] id: CCO:C0001551 name: plasma membrane proton-transporting V-type ATPase complex namespace: cellular_component def: "A proton-transporting two-sector ATPase complex found in the plasma membrane." [GOC:mah] synonym: "plasma membrane hydrogen ion-transporting ATPase" EXACT [] xref: GO:0033181 is_a: CCO:C0001546 ! proton-transporting V-type ATPase complex [Term] id: CCO:C0001552 name: dolichol-phosphate-mannose synthase complex namespace: cellular_component def: "A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively." [PMID:10835346] synonym: "dolichyl-phosphate beta-D-mannosyltransferase complex" EXACT [] synonym: "DPM synthase complex" EXACT [] xref: GO:0033185 is_a: CCO:C0001276 ! mannosyltransferase complex [Term] id: CCO:C0001553 name: CAF-1 complex namespace: cellular_component def: "A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48." [PMID:17065558, PMID:17083276] synonym: "chromatin assembly factor 1 complex" EXACT [] xref: GO:0033186 is_a: CCO:C0000281 ! chromatin assembly complex [Term] id: CCO:C0001554 name: Lsd1/2 complex namespace: cellular_component def: "A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast." [GOC:vw, PMID:17371846, PMID:17434129, PMID:17440621] synonym: "SAPHIRE complex" EXACT [PMID:17371846] synonym: "Swm complex" EXACT [PMID:17440621] synonym: "Swm1/2 complex" RELATED [PMID:17440621] xref: GO:0033193 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0001555 name: DNA helicase complex namespace: cellular_component def: "A protein complex that possesses DNA helicase activity." [GOC:mah] subset: goslim_pir xref: GO:0033202 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001556 name: DNA helicase A complex namespace: cellular_component def: "A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction." [PMID:9341218] xref: GO:0033203 is_a: CCO:C0001555 ! DNA helicase complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001557 name: vacuolar transporter chaperone complex namespace: cellular_component def: "A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p." [PMID:11823419, PMID:17079729] synonym: "VTC complex" EXACT [] xref: GO:0033254 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001558 name: SAS acetyltransferase complex namespace: cellular_component def: "A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p." [PMID:11731480, PMID:12626510, PMID:15788653] synonym: "SAS-I complex" EXACT [] xref: GO:0033255 is_a: CCO:C0001475 ! Piccolo NuA4 histone acetyltransferase complex [Term] id: CCO:C0001559 name: I-kappaB/NF-kappaB complex namespace: cellular_component def: "A protein complex containing an I-kappaB protein and one or more copies of an NF-kappaB protein; mediates regulation of NF-kappaB activity by I-kappaB." [GOC:mah, PMID:9407099] subset: goslim_pir xref: GO:0033256 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001560 name: Bcl3/NF-kappaB2 complex namespace: cellular_component def: "A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription." [GOC:mah, PMID:9407099] synonym: "Bcl3-NFKB2 complex" RELATED [] synonym: "Bcl3-p52 complex" EXACT [] xref: GO:0033257 is_a: CCO:C0001559 ! I-kappaB/NF-kappaB complex relationship: location_of CCO:B0013164 ! NFKB2_HUMAN-Phosphoserine713 relationship: location_of CCO:B0041126 ! BCL3_HUMAN-Phosphoserine394 [Term] id: CCO:C0001561 name: CORVET complex namespace: cellular_component def: "A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p." [PMID:17488625] xref: GO:0033263 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001859 ! endosomal part [Term] id: CCO:C0001562 name: axon part namespace: cellular_component def: "A cell projection part that is part of an axon." [GOC:mh] xref: GO:0033267 is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0001004 ! axon [Term] id: CCO:C0001563 name: node of Ranvier namespace: cellular_component def: "An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed." [GOC:mh] xref: GO:0033268 is_a: CCO:C0001562 ! axon part [Term] id: CCO:C0001564 name: internode region of axon namespace: cellular_component def: "An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath." [GOC:mah, GOC:mh] xref: GO:0033269 is_a: CCO:C0001562 ! axon part [Term] id: CCO:C0001565 name: paranode region of axon namespace: cellular_component def: "An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath." [GOC:mah, GOC:mh] xref: GO:0033270 is_a: CCO:C0001562 ! axon part [Term] id: CCO:C0001566 name: transcription factor TFTC complex namespace: cellular_component def: "A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity." [PMID:10373431, PMID:9603525] xref: GO:0033276 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000811 ! DNA-directed RNA polymerase II, holoenzyme [Term] id: CCO:C0001567 name: ribosomal subunit namespace: cellular_component def: "Either of the two ribonucleoprotein complexes that associate to form a ribosome." [GOC:mah] subset: gosubset_prok xref: GO:0033279 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000407 ! ribosome [Term] id: CCO:C0001568 name: TAT protein translocation system complex namespace: cellular_component def: "A complex of three proteins integral to the bacterial cytoplasmic membrane involved in translocation of folded proteins across the bacterial cytoplasmic membrane." [GOC:pamgo_curators] xref: GO:0033281 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001569 name: protein C inhibitor-acrosin complex namespace: cellular_component def: "A heterodimeric protein complex of protein C inhibitor and acrosin; complex formation inhibits the protease activity of acrosin." [PMID:11120760, PMID:7521127] synonym: "PCI-ACR complex" EXACT [] synonym: "PCI-acrosin complex" EXACT [] xref: GO:0033282 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000194 ! acrosomal membrane [Term] id: CCO:C0001570 name: intraconoid microtubule namespace: cellular_component def: "A microtubule located such that it threads through the conoid and projects through the polar ring." [GOC:mah, PMID:11901169, PMID:16518471] xref: GO:0033289 is_a: CCO:C0000434 ! microtubule relationship: part_of CCO:C0000909 ! apical complex [Term] id: CCO:C0001571 name: eukaryotic 48S preinitiation complex namespace: cellular_component def: "A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA." [GOC:hjd, PMID:15145049] synonym: "eukaryotic 48S initiation complex" RELATED [] synonym: "eukaryotic 48S pre-initiation complex" EXACT [] xref: GO:0016283 xref: GO:0033290 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001572 name: eukaryotic 80S initiation complex namespace: cellular_component def: "A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region." [GOC:hjd, PMID:15145049] xref: GO:0033291 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001573 name: SBF transcription complex namespace: cellular_component def: "A protein complex that acts as a transcription factor, composed of a regulatory subunit (Swi6) and a DNA-binding protein (Swi4), that activates gene expression during the G1/S transition of the cell cycle. Binds to a sequence motif called the SCB element (Swi4/6 cell cycle box, CACGAAA) which acts as a late Gl-specific UAS element in genes predominantly involved in budding, and in membrane and cell wall biosynthesis." [PMID:7917338] xref: GO:0033309 is_a: CCO:C0000272 ! transcription factor complex [Term] id: CCO:C0001574 name: chromatoid body namespace: cellular_component def: "A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182)." [PMID:17183363] xref: GO:0033391 is_a: CCO:C0001019 ! ribonucleoprotein complex relationship: location_of CCO:B0059144 ! DDX25_HUMAN [Term] id: CCO:C0001575 name: HULC complex namespace: cellular_component def: "A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2." [GOC:mah, PMID:17363370, PMID:17374714] xref: GO:0033503 is_a: CCO:C0000026 ! ubiquitin ligase complex is_a: CCO:C0001219 ! ubiquitin conjugating enzyme complex relationship: part_of CCO:C0000119 ! heterochromatin [Term] id: CCO:C0001576 name: monopolin complex namespace: cellular_component def: "A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits." [GOC:mah, GOC:rb, PMID:17627824] synonym: "monopolin subcomplex Csm1/Lrs4" NARROW [] synonym: "Pcs1/Mde4 complex" NARROW [] xref: GO:0033551 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000104 ! condensed chromosome kinetochore [Term] id: CCO:C0001577 name: rDNA heterochromatin namespace: cellular_component def: "A region of heterochromatin located at the rDNA repeats in a chromosome." [GOC:mah] synonym: "ribosomal DNA heterochromatin" EXACT [] xref: GO:0033553 is_a: CCO:C0000119 ! heterochromatin [Term] id: CCO:C0001578 name: Slx1-Slx4 complex namespace: cellular_component def: "A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes." [PMID:14528010, PMID:16467377] xref: GO:0033557 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001873 ! nuclear chromosome part [Term] id: CCO:C0001579 name: ESCRT-0 complex namespace: cellular_component def: "A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals." [GOC:rb, PMID:12055639, PMID:17543868] synonym: "Hrs/STAM complex" EXACT [] synonym: "Vps27p-Hse1p complex" EXACT [] xref: GO:0033565 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001859 ! endosomal part [Term] id: CCO:C0001580 name: high affinity iron permease complex namespace: cellular_component def: "A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell." [GOC:jp, PMID:16522632, PMID:8599111] xref: GO:0033573 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001581 name: rhabdomere membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the rhabdomere." [GOC:mah] xref: GO:0033583 is_a: CCO:C0001173 ! cell projection membrane relationship: part_of CCO:C0000771 ! rhabdomere [Term] id: CCO:C0001582 name: Elongator holoenzyme complex namespace: cellular_component def: "A heterohexameric protein complex that is involved in tRNA modification, and exerts indirect effects on transcriptional elongation and exocytosis. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes." [GOC:mah, PMID:11689709, PMID:17018299] synonym: "Elongator core complex" RELATED [] xref: GO:0033588 xref: GO:0033589 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0065045 ! ELP4_HUMAN-Phosphoserine42 [Term] id: CCO:C0001583 name: BRCA2-MAGE-D1 complex namespace: cellular_component def: "A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth." [PMID:15930293] xref: GO:0033593 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001649 ! BRCA2_HUMAN [Term] id: CCO:C0001584 name: TSC1-TSC2 complex namespace: cellular_component def: "A heterodimeric protein complex consisting of tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway." [PMID:10585443, PMID:17121544, PMID:9580671] synonym: "tuberin-hamartin complex " EXACT [] synonym: "tuberous sclerosis complex" EXACT [] xref: GO:0033596 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0013172 ! NFL_HUMAN-Phosphoserine472 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 [Term] id: CCO:C0001585 name: mitotic checkpoint complex namespace: cellular_component def: "A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20." [PMID:10704439, PMID:11535616, PMID:11726501, PMID:17650307] synonym: "MCC" EXACT [] xref: GO:0033597 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001586 name: SOD1-Bcl-2 complex namespace: cellular_component def: "A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway." [PMID:15233914, PMID:16790527] xref: GO:0033607 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001587 name: Mei2 nuclear dot namespace: cellular_component def: "A nuclear body that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I." [PMID:12808043] synonym: "Mei2 dot" EXACT [] xref: GO:0033620 is_a: CCO:C0000817 ! nuclear body [Term] id: CCO:C0001588 name: host cell part namespace: cellular_component def: "Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] subset: gosubset_prok xref: GO:0033643 is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0001804 ! host cell [Term] id: CCO:C0001589 name: host cell membrane namespace: cellular_component def: "Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] subset: gosubset_prok xref: GO:0033644 is_a: CCO:C0001588 ! host cell part [Term] id: CCO:C0001590 name: host cell endomembrane system namespace: cellular_component def: "A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] xref: GO:0033645 is_a: CCO:C0001589 ! host cell membrane [Term] id: CCO:C0001591 name: host intracellular part namespace: cellular_component def: "Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] subset: gosubset_prok xref: GO:0033646 is_a: CCO:C0001803 ! intracellular region of host [Term] id: CCO:C0001592 name: host intracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] subset: gosubset_prok xref: GO:0033647 is_a: CCO:C0001591 ! host intracellular part [Term] id: CCO:C0001594 name: host cell mitochondrion namespace: cellular_component def: "A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] synonym: "host mitochondria" EXACT [] xref: GO:0033650 is_a: CCO:C0001599 ! host cell cytoplasm part is_a: CCO:C0002126 ! host intracellular membrane-bounded organelle [Term] id: CCO:C0001595 name: host cell plastid namespace: cellular_component def: "Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] xref: GO:0033651 is_a: CCO:C0001599 ! host cell cytoplasm part is_a: CCO:C0002126 ! host intracellular membrane-bounded organelle [Term] id: CCO:C0001596 name: host cell chloroplast namespace: cellular_component def: "A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] xref: GO:0033652 is_a: CCO:C0001595 ! host cell plastid [Term] id: CCO:C0001597 name: host cell chloroplast part namespace: cellular_component def: "Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] synonym: "host chloroplast component" EXACT [] xref: GO:0033653 is_a: CCO:C0001596 ! host cell chloroplast [Term] id: CCO:C0001598 name: host cell chloroplast thylakoid membrane namespace: cellular_component def: "Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] xref: GO:0033654 is_a: CCO:C0001597 ! host cell chloroplast part [Term] id: CCO:C0001599 name: host cell cytoplasm part namespace: cellular_component def: "Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] subset: gosubset_prok synonym: "cytoplasm component" BROAD [] xref: GO:0033655 is_a: CCO:C0001591 ! host intracellular part relationship: part_of CCO:C0001009 ! host cell cytoplasm [Term] id: CCO:C0001600 name: pericanalicular vesicle namespace: cellular_component def: "A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes." [PMID:15763347, PMID:9790571] xref: GO:0033675 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0001601 name: Clr6 histone deacetylase complex I/I' namespace: cellular_component def: "A histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe)." [GOC:vw, PMID:17450151] xref: GO:0033698 is_a: CCO:C0000008 ! histone deacetylase complex [Term] id: CCO:C0001602 name: SUMO-targeted ubiquitin ligase complex namespace: cellular_component def: "A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes." [GOC:vw, PMID:17762864, PMID:17762865] xref: GO:0033768 is_a: CCO:C0000027 ! nuclear ubiquitin ligase complex [Term] id: CCO:C0001603 name: basal labyrinth namespace: cellular_component def: "A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane." [GOC:mah, GOC:sart, PMID:11640882] xref: GO:0033774 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0001897 ! basal part of cell [Term] id: CCO:C0001604 name: subapical complex namespace: cellular_component def: "The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells." [PMID:11752566, PMID:12500938] synonym: "SAC" BROAD [] xref: GO:0035003 is_a: CCO:C0000463 ! intercellular junction relationship: location_of CCO:B0025070 ! PDZD3_HUMAN relationship: part_of CCO:C0001769 ! apical junction complex [Term] id: CCO:C0001605 name: polytene chromosome, telomeric region namespace: cellular_component def: "The terminal region of a polytene chromosome." [GOC:bf] xref: GO:0035012 is_a: CCO:C0000108 ! chromosome, telomeric region relationship: part_of CCO:C0000298 ! polytene chromosome [Term] id: CCO:C0001608 name: phosphoinositide 3-kinase complex, class III namespace: cellular_component def: "A complex containing a heterodimer of a catalytic Class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI)." [GOC:bf, PMID:9255069] synonym: "class III PI3K complex" EXACT [] xref: GO:0035032 is_a: CCO:C0000492 ! phosphoinositide 3-kinase complex [Term] id: CCO:C0001609 name: RCAF complex namespace: cellular_component def: "A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4." [GOC:bf, PMID:10591219] synonym: "replication-coupling assembly factor complex" EXACT [] xref: GO:0035059 is_a: CCO:C0000806 ! chromatin remodeling complex [Term] id: CCO:C0001610 name: brahma complex namespace: cellular_component def: "A multi-subunit ATP-dependent chromatin remodeling complex, a counterpart of the SWI/SNF complex that contains the ATPase product of the Drosophila brahma gene." [GOC:bf, PMID:10809665, PMID:12482982] synonym: "BRM complex" EXACT [] xref: GO:0035060 is_a: CCO:C0000806 ! chromatin remodeling complex [Term] id: CCO:C0001611 name: interchromatin granule namespace: cellular_component def: "A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs)." [GOC:bf, PMID:10984439] synonym: "ICG" EXACT [] xref: GO:0035061 is_a: CCO:C0000817 ! nuclear body [Term] id: CCO:C0001612 name: omega speckle namespace: cellular_component def: "A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs)." [GOC:bf, PMID:10984439] xref: GO:0035062 is_a: CCO:C0000820 ! nuclear speck [Term] id: CCO:C0001613 name: micro-ribonucleoprotein complex namespace: cellular_component def: "A complex containing both protein and micro-RNA (miRNA) molecules. miRNAs are approximately 22 nucleotide noncoding RNAs derived from endogenous genes; they are processed from the stem of a longer hairpin like structure termed a pre-miRNA." [GOC:bf, PMID:14559182] synonym: "miRNP complex" EXACT [] xref: GO:0035068 is_a: CCO:C0001019 ! ribonucleoprotein complex [Term] id: CCO:C0001614 name: cilium axoneme namespace: cellular_component def: "The bundle of microtubules and associated proteins that forms the core of cilia in eukaryotic cells and is responsible for their movements." [GOC:bf, ISBN:0198547684] xref: GO:0035085 is_a: CCO:C0000482 ! axoneme is_a: CCO:C0001860 ! cilium part relationship: location_of CCO:B0006028 ! DYH9_HUMAN [Term] id: CCO:C0001615 name: flagellar axoneme namespace: cellular_component def: "The bundle of microtubules and associated proteins that forms the core of flagellar in eukaryotic cells and is responsible for their movements." [GOC:bf, ISBN:0198547684] synonym: "flagellum axoneme" EXACT [] xref: GO:0035086 is_a: CCO:C0000482 ! axoneme is_a: CCO:C0001861 ! microtubule-based flagellum part [Term] id: CCO:C0001616 name: histone methyltransferase complex namespace: cellular_component def: "A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins." [GOC:bf] subset: goslim_pir xref: GO:0035097 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0005614 ! ASH2L_HUMAN relationship: location_of CCO:B0013722 ! RBBP5_HUMAN-Phosphothreonine252 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:C0001617 name: ESC/E(Z) complex namespace: cellular_component def: "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12." [GOC:bf, PMID:12408863, PMID:12408864] synonym: "Extra Sex Combs/Enhancer of Zeste complex" EXACT [] xref: GO:0035098 is_a: CCO:C0001285 ! PcG protein complex is_a: CCO:C0001616 ! histone methyltransferase complex relationship: location_of CCO:B0043864 ! EED_HUMAN relationship: location_of CCO:B0056036 ! SUZ12_HUMAN [Term] id: CCO:C0001618 name: FACT complex namespace: cellular_component def: "An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer." [GOC:bf, GOC:expert_ks, GOC:expert_ras, GOC:expert_tf, GOC:krc, PMID:12934006, PMID:12934007, PMID:16678108] synonym: "Facilitates chromatin transcription complex" EXACT [] xref: GO:0035101 is_a: CCO:C0000523 ! transcription elongation factor complex [Term] id: CCO:C0001619 name: PRC1 complex namespace: cellular_component def: "An insect multiprotein complex containing the products of many of the Polycomb Group genes including Polycomb, Posterior sex combs, polyhomeotic and Sex comb on midleg. The Polycomb Group proteins are required for stable long-term maintenance of transcriptionally repressed states and the PRC1 complex directly antagonizes ATP-dependent remodeling of nucleosomal arrays." [GOC:bf, PMID:10412979] synonym: "Polycomb repressive complex 1" EXACT [] xref: GO:0035102 is_a: CCO:C0001285 ! PcG protein complex [Term] id: CCO:C0001620 name: exon-exon junction complex namespace: cellular_component def: "A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay." [PMID:11532962, PMID:11743026] synonym: "EJC" EXACT [] xref: GO:0035145 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001621 name: germline ring canal outer rim namespace: cellular_component def: "An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues." [PMID:12435357, PMID:7925006] comment: See also the fly_anatomy.ontology term 'outer nurse cell ring canal rim ; FBbt:00004882'. xref: GO:0035182 is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0001895 ! germline ring canal [Term] id: CCO:C0001622 name: germline ring canal inner rim namespace: cellular_component def: "A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins." [PMID:10556087, PMID:7925006, PMID:9093858] comment: See also the fly_anatomy.ontology term 'inner nurse cell ring canal rim ; FBbt:00004881'. xref: GO:0035183 is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0001895 ! germline ring canal [Term] id: CCO:C0001623 name: Rb-E2F complex namespace: cellular_component def: "A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression." [PMID:14616073] synonym: "retinoblastoma-E2F complex" EXACT [] xref: GO:0035189 is_a: CCO:C0000272 ! transcription factor complex [Term] id: CCO:C0001624 name: cytoneme namespace: cellular_component def: "A long, thin and polarized actin-based extension that projects from a cell and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um." [PMID:10367889, PMID:10675901] subset: goslim_pir xref: GO:0035230 is_a: CCO:C0001706 ! cell projection [Term] id: CCO:C0001625 name: ciliary rootlet namespace: cellular_component def: "A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm." [PMID:12427867] xref: GO:0035253 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001860 ! cilium part relationship: location_of CCO:B0005599 ! KINH_HUMAN relationship: location_of CCO:B0006166 ! KIF5A_HUMAN relationship: location_of CCO:B0011349 ! CROCC_HUMAN-Phosphoserine1619 [Term] id: CCO:C0001626 name: NuA4 histone acetyltransferase complex namespace: cellular_component def: "A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60)." [GOC:ecd, PMID:10966108, PMID:14966270] synonym: "TIP60 histone acetylase complex" EXACT [] synonym: "TIP60 histone acetyltransferase complex" EXACT [] xref: GO:0035267 is_a: CCO:C0001724 ! H4/H2A histone acetyltransferase complex relationship: location_of CCO:B0002249 ! RUVB1_HUMAN relationship: location_of CCO:B0005350 ! TRRAP_HUMAN relationship: location_of CCO:B0005364 ! RUVB2_HUMAN relationship: location_of CCO:B0010433 ! ACL6A_HUMAN-Phosphoserine233 relationship: location_of CCO:B0010440 ! ACTB_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0014378 ! TIP60_HUMAN-Phosphoserine86 [Term] id: CCO:C0001627 name: Hedgehog signaling complex namespace: cellular_component def: "A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila)." [PMID:10825151, PMID:15057936] synonym: "Hedgehog signalling complex" EXACT [] synonym: "HSC" EXACT [] xref: GO:0035301 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001628 name: interleukin-12 receptor complex namespace: cellular_component def: "Complex that binds interleukin-12; comprises an alpha and a beta subunit." [GOC:mah, PMID:10971505] xref: GO:0042022 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001629 name: host cell nucleus namespace: cellular_component def: "A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] subset: gosubset_prok xref: GO:0033649 xref: GO:0042025 is_a: CCO:C0002126 ! host intracellular membrane-bounded organelle relationship: part_of CCO:C0001803 ! intracellular region of host [Term] id: CCO:C0001630 name: T cell receptor complex namespace: cellular_component def: "A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains." [GOC:mah, ISBN:0781735149 "Fundamental Immunology"] synonym: "T lymphocyte receptor complex" EXACT [] synonym: "T-cell receptor complex" EXACT [] synonym: "T-lymphocyte receptor complex" EXACT [] synonym: "TCR" EXACT [] xref: GO:0042101 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0005740 ! CD4_HUMAN relationship: location_of CCO:B0054856 ! CD8A_HUMAN relationship: location_of CCO:B0054916 ! CD3E_HUMAN relationship: location_of CCO:B0054983 ! CD8B_HUMAN relationship: location_of CCO:B0056916 ! TRAT1_HUMAN relationship: location_of CCO:B0058559 ! CAR11_HUMAN relationship: location_of CCO:B0064154 ! CD3D_HUMAN-Phosphotyrosine160 relationship: location_of CCO:B0064160 ! CD3G_HUMAN-Phosphotyrosine171 relationship: location_of CCO:B0064164 ! CD3Z_HUMAN-Phosphotyrosine83 relationship: location_of CCO:B0067505 ! KSYK_HUMAN-Phosphotyrosine323 relationship: location_of CCO:B0071950 ! ZAP70_HUMAN-Phosphotyrosine315 relationship: part_of CCO:C0000186 ! immunological synapse [Term] id: CCO:C0001631 name: alpha-beta T cell receptor complex namespace: cellular_component def: "A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein." [GOC:mah, ISBN:0781735149 "Fundamental Immunology"] synonym: "alpha-beta T lymphocyte receptor complex" EXACT [] synonym: "alpha-beta T-cell receptor complex" EXACT [] synonym: "alpha-beta T-lymphocyte receptor complex" EXACT [] synonym: "alpha-beta TCR complex" EXACT [] xref: GO:0042105 is_a: CCO:C0001630 ! T cell receptor complex [Term] id: CCO:C0001632 name: gamma-delta T cell receptor complex namespace: cellular_component def: "A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein." [GOC:mah, ISBN:0781735149 "Fundamental Immunology"] synonym: "gamma-delta T lymphocyte receptor complex" EXACT [] synonym: "gamma-delta T-cell receptor complex" EXACT [] synonym: "gamma-delta T-lymphocyte receptor complex" EXACT [] synonym: "gamma-delta TCR complex" EXACT [] xref: GO:0042106 is_a: CCO:C0001630 ! T cell receptor complex [Term] id: CCO:C0001633 name: nematocyst namespace: cellular_component def: "An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus." [GOC:jl, UniProtKB:P01533] synonym: "cnidocyst" EXACT [] xref: GO:0042151 is_a: CCO:C0001867 ! cell cortex part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle [Term] id: CCO:C0001634 name: plastid membrane namespace: cellular_component def: "Either of the lipid bilayers that surround a plastid and form the plastid envelope." [GOC:mah] xref: GO:0042170 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000654 ! plastid envelope [Term] id: CCO:C0001635 name: nuclear envelope-endoplasmic reticulum network namespace: cellular_component def: "The continuous network of membranes encompassing the outer nuclear membrane and the endoplasmic reticulum." [GOC:jl] synonym: "NE-ER continuum" EXACT [] synonym: "NE-ER network" EXACT [] synonym: "nuclear envelope-endoplasmic reticulum continuum" EXACT [] synonym: "nuclear envelope-ER network" EXACT [] xref: GO:0042175 is_a: CCO:C0000766 ! membrane is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: part_of CCO:C0000733 ! endomembrane system [Term] id: CCO:C0001636 name: nuclear RNA export factor complex namespace: cellular_component def: "A complex of NXF1 and NXF2 required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm." [UniProtKB:Q9U1H9] synonym: "Mex67-Mtr2 complex" EXACT [] synonym: "NXF1-NXT1 complex" EXACT [] synonym: "TAP-p15 complex" EXACT [] xref: GO:0042272 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part relationship: location_of CCO:B0063661 ! ATX1_HUMAN-Phosphoserine238 [Term] id: CCO:C0001637 name: paraspeckles namespace: cellular_component def: "Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei." [GOC:jl, PMID:11790299] xref: GO:0042382 is_a: CCO:C0000817 ! nuclear body relationship: location_of CCO:B0065891 ! CPSF5_HUMAN-Phosphotyrosine40 relationship: location_of CCO:B0065893 ! CPSF6_HUMAN-Phosphothreonine404 [Term] id: CCO:C0001638 name: sarcolemma namespace: cellular_component def: "The outer membrane of a muscle fiber, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0042383 is_a: CCO:C0000444 ! plasma membrane relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0012493 ! K2C8_HUMAN-Phosphoserine27 relationship: location_of CCO:B0030971 ! IRK11_HUMAN relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0054765 ! GNAS3_HUMAN relationship: location_of CCO:B0055097 ! LOX12_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0064890 ! DTBP1_HUMAN-Phosphoserine321 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 [Term] id: CCO:C0001639 name: myosin III complex namespace: cellular_component def: "A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain." [GOC:jl, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0042385 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001640 name: nuclear inclusion body namespace: cellular_component def: "Intranuclear foci at which aggregated proteins have been sequestered." [GOC:jl] xref: GO:0042405 is_a: CCO:C0000775 ! inclusion body is_a: CCO:C0001847 ! nuclear part relationship: location_of CCO:B0013106 ! NBN_HUMAN-Phosphoserine432 relationship: location_of CCO:B0018046 ! NXF1_HUMAN relationship: location_of CCO:B0063661 ! ATX1_HUMAN-Phosphoserine238 [Term] id: CCO:C0001641 name: extrinsic to endoplasmic reticulum membrane namespace: cellular_component def: "Loosely bound to one surface of the endoplasmic reticulum membrane, but not integrated into the hydrophobic region." [GOC:jl, http://cancerweb.ncl.ac.uk/] synonym: "extrinsic to ER membrane" EXACT [] xref: GO:0042406 is_a: CCO:C0001199 ! extrinsic to organelle membrane is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0001642 name: melanosome namespace: cellular_component def: "A tissue-specific, membrane bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells." [GOC:jl, PMID:11584301] xref: GO:0042470 is_a: CCO:C0002006 ! pigment granule relationship: location_of CCO:B0001648 ! TCPD_HUMAN relationship: location_of CCO:B0006151 ! PDIA1_HUMAN relationship: location_of CCO:B0006345 ! CATB_HUMAN relationship: location_of CCO:B0010365 ! 1433B_HUMAN-Phosphoserine186 relationship: location_of CCO:B0010366 ! 1433E_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010373 ! 1433Z_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0010381 ! 4F2_HUMAN-Phosphothreonine5 relationship: location_of CCO:B0010556 ! ANXA2_HUMAN-N-acetylserine2 relationship: location_of CCO:B0010562 ! ANXA6_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0010637 ! AT1A1_HUMAN-Phosphothreonine219 relationship: location_of CCO:B0011948 ! GNA13_HUMAN-Phosphothreonine203 relationship: location_of CCO:B0012271 ! HS90B_HUMAN-Phosphothreonine297 relationship: location_of CCO:B0013244 ! NP1L1_HUMAN-Phosphoserine10 relationship: location_of CCO:B0013659 ! RAC1_HUMAN-ADP-ribosylasparagine39 relationship: location_of CCO:B0013707 ! RAN_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0013718 ! RB27A_HUMAN-Cysteine methyl ester221 relationship: location_of CCO:B0023550 ! RAB5C_HUMAN relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0023553 ! RAB5B_HUMAN relationship: location_of CCO:B0031331 ! HS90A_HUMAN-Phosphotyrosine313 relationship: location_of CCO:B0031334 ! HSP7C_HUMAN-Phosphotyrosine41 relationship: location_of CCO:B0034884 ! ITB1_HUMAN-Phosphotyrosine783 relationship: location_of CCO:B0040688 ! RPN1_HUMAN relationship: location_of CCO:B0042031 ! PDIA3_HUMAN relationship: location_of CCO:B0055025 ! ENPL_HUMAN relationship: location_of CCO:B0055324 ! CAPG_HUMAN relationship: location_of CCO:B0055446 ! MMP14_HUMAN relationship: location_of CCO:B0055602 ! RAB2A_HUMAN relationship: location_of CCO:B0055775 ! PRDX1_HUMAN relationship: location_of CCO:B0056027 ! GPNMB_HUMAN relationship: location_of CCO:B0056054 ! RAB35_HUMAN relationship: location_of CCO:B0058062 ! NICA_HUMAN relationship: location_of CCO:B0062997 ! CLH1_HUMAN relationship: location_of CCO:B0063067 ! CALX_HUMAN relationship: location_of CCO:B0063209 ! CALU_HUMAN relationship: location_of CCO:B0063255 ! CN37_HUMAN relationship: location_of CCO:B0063256 ! TMM33_HUMAN relationship: location_of CCO:B0063733 ! BASI_HUMAN-Phosphoserine362 relationship: location_of CCO:B0065230 ! AAAT_HUMAN-Phosphoserine535 relationship: location_of CCO:B0066134 ! FAS_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066894 ! HPS4_HUMAN-Phosphoserine355 relationship: location_of CCO:B0069187 ! PDIA6_HUMAN-Phosphoserine428 relationship: location_of CCO:B0069208 ! PEDF_HUMAN-Phosphoserine24 relationship: location_of CCO:B0069696 ! RAB7A_HUMAN-Cysteine methyl ester207 relationship: location_of CCO:B0070367 ! SDCB1_HUMAN-Phosphotyrosine91 relationship: location_of CCO:B0070680 ! SND1_HUMAN-Phosphothreonine429 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 [Term] id: CCO:C0001643 name: MCM complex namespace: cellular_component def: "A hexameric protein complex required for the initiation and regulation of DNA replication." [GOC:jl, PMID:11282021] synonym: "mini-chromosome maintenance complex" EXACT [] xref: GO:0042555 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0001589 ! MCM7_HUMAN relationship: part_of CCO:C0001793 ! nuclear replication fork [Term] id: CCO:C0001644 name: importin alpha-subunit nuclear export complex namespace: cellular_component def: "A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha-subunit/CAS/Ran, and which functions to shuttle the importin alpha-subunit out of the nucleus through the nuclear pore." [GOC:jl, PMID:9323123, PMID:9323134] xref: GO:0042563 is_a: CCO:C0001119 ! nucleocytoplasmic shuttling complex [Term] id: CCO:C0001645 name: NLS-dependent protein nuclear import complex namespace: cellular_component def: "A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha and beta-subunits and any protein which has a nuclear localization sequence (NLS). The complex acts to import proteins with an NLS into the nucleus through a nuclear pore." [GOC:jl, PMID:9323123, PMID:9323134] xref: GO:0042564 is_a: CCO:C0001119 ! nucleocytoplasmic shuttling complex relationship: location_of CCO:B0068027 ! MBB1A_HUMAN-Phosphothreonine1190 [Term] id: CCO:C0001646 name: RNA nuclear export complex namespace: cellular_component def: "A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore." [GOC:jl, PMID:9323123] xref: GO:0042565 is_a: CCO:C0001119 ! nucleocytoplasmic shuttling complex [Term] id: CCO:C0001647 name: hydrogenosome namespace: cellular_component def: "A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation." [GOC:jl, PMID:11197234, PMID:11293569] subset: goslim_pir xref: GO:0042566 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0001648 name: insulin-like growth factor ternary complex namespace: cellular_component def: "A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development." [GOC:jl, PMID:12239079] synonym: "IGF ternary complex" EXACT [] xref: GO:0042567 is_a: CCO:C0000829 ! insulin-like growth factor binding protein complex relationship: location_of CCO:B0048872 ! ALS_HUMAN [Term] id: CCO:C0001649 name: insulin-like growth factor binary complex namespace: cellular_component def: "A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development." [GOC:jl, PMID:12239079] synonym: "IGF binary complex" EXACT [] xref: GO:0042568 is_a: CCO:C0000829 ! insulin-like growth factor binding protein complex [Term] id: CCO:C0001650 name: immunoglobulin complex, circulating namespace: cellular_component def: "A multi-subunit complex that functions as an antibody and circulates in the blood, lymph, mucosal areas, and other fluids of the body. In its basic form, circulating immunoglobulin is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms are polymers of the basic structure and contain additional components such as J-chain and the secretory component." [ISBN:0781735149 "Fundamental Immunology"] xref: GO:0042571 is_a: CCO:C0000888 ! immunoglobulin complex is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0001651 name: DNA polymerase complex namespace: cellular_component def: "A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA." [GOC:jl, http://cancerweb.ncl.ac.uk/, PMID:12045093] subset: goslim_pir subset: gosubset_prok xref: GO:0042575 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001652 name: microbody namespace: cellular_component def: "Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir xref: GO:0042579 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0001653 name: mannosome namespace: cellular_component def: "A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction." [GOC:jl, PMID:11912051, PMID:9799531] xref: GO:0042580 is_a: CCO:C0000359 ! peroxisome [Term] id: CCO:C0001654 name: specific granule namespace: cellular_component def: "Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase." [GOC:jl, http://cancerweb.ncl.ac.uk/, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary", PMID:7334549] synonym: "secondary granule" EXACT [] xref: GO:0042581 is_a: CCO:C0000985 ! secretory granule [Term] id: CCO:C0001655 name: azurophil granule namespace: cellular_component def: "Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid." [GOC:jl, http://cancerweb.ncl.ac.uk/] synonym: "primary granule" EXACT [] xref: GO:0042582 is_a: CCO:C0000349 ! primary lysosome is_a: CCO:C0000985 ! secretory granule relationship: location_of CCO:B0055114 ! CAP7_HUMAN relationship: location_of CCO:B0057234 ! Q86SR2_HUMAN [Term] id: CCO:C0001656 name: chromaffin granule namespace: cellular_component def: "Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0042583 is_a: CCO:C0000985 ! secretory granule relationship: location_of CCO:B0054941 ! DOPO_HUMAN [Term] id: CCO:C0001657 name: chromaffin granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0042584 is_a: CCO:C0001031 ! secretory granule membrane relationship: part_of CCO:C0001656 ! chromaffin granule [Term] id: CCO:C0001658 name: germinal vesicle namespace: cellular_component def: "The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity." [GOC:jl, GOC:mtg_sensu, http://cancerweb.ncl.ac.uk/] synonym: "primary oocyte nucleus" EXACT [] xref: GO:0042585 is_a: CCO:C0000179 ! female germ cell nucleus [Term] id: CCO:C0001659 name: glycogen granule namespace: cellular_component def: "Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface." [GOC:jl, http://148.216.10.83/cellbio/the_mi19.gif, PMID:12179957] synonym: "glycogen particle" EXACT [] xref: GO:0042587 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0066134 ! FAS_HUMAN-N-acetylmethionine1 [Term] id: CCO:C0001660 name: zymogen granule namespace: cellular_component def: "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0042588 is_a: CCO:C0000985 ! secretory granule relationship: location_of CCO:B0054785 ! RAB3D_HUMAN [Term] id: CCO:C0001661 name: zymogen granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a zymogen granule." [GOC:jl] xref: GO:0042589 is_a: CCO:C0001031 ! secretory granule membrane relationship: location_of CCO:B0001940 ! CUZD1_HUMAN relationship: location_of CCO:B0038128 ! TMED2_HUMAN relationship: location_of CCO:B0071421 ! TMEDA_HUMAN-Omega-N-methylated arginine171 relationship: part_of CCO:C0001660 ! zymogen granule [Term] id: CCO:C0001662 name: periplasmic space namespace: cellular_component def: "The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or inner membrane and cell wall (Fungi)." [GOC:go_curators] subset: goslim_pir subset: gosubset_prok synonym: "periplasm" EXACT [] xref: GO:0005620 xref: GO:0042597 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001663 name: vesicular fraction namespace: cellular_component def: "Any of the small, heterogeneous, artifactual, vesicular particles that are formed when some cells are homogenized." [GOC:jl] comment: Note that this term refers to disrupted cells, and does not necessarily correspond to any specific structure(s) in an intact cell. subset: gosubset_prok xref: GO:0042598 is_a: CCO:C0000244 ! membrane fraction relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 [Term] id: CCO:C0001664 name: lamellar body namespace: cellular_component def: "A membrane bounded organelle, specialized for the storage and secretion various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome." [GOC:jl, PMID:12243725] synonym: "keratinosome" EXACT [] synonym: "lamellar granule" EXACT [] synonym: "membrane-coating granule" EXACT [] synonym: "Odland body" EXACT [] xref: GO:0042599 is_a: CCO:C0000985 ! secretory granule relationship: location_of CCO:B0058862 ! ISK5_HUMAN [Term] id: CCO:C0001665 name: chorion namespace: cellular_component def: "A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish." [GOC:jl, http://cancerweb.ncl.ac.uk/, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] comment: Note that this term does not refer to the extraembryonic membrane surrounding the embryo of amniote vertebrates as this is an anatomical structure and is therefore not covered by GO. subset: goslim_pir xref: GO:0042600 is_a: CCO:C0000999 ! external encapsulating structure [Term] id: CCO:C0001666 name: endospore-forming forespore namespace: cellular_component def: "Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions." [GOC:jl, GOC:mtg_sensu, ISBN:0697286029] subset: gosubset_prok synonym: "forespore (sensu Bacteria)" EXACT [] xref: GO:0042601 is_a: CCO:C0002134 ! intracellular immature spore [Term] id: CCO:C0001667 name: capsule namespace: cellular_component def: "A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and can not be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication." [GOC:mlg] subset: gosubset_prok synonym: "capsule (sensu Bacteria)" EXACT [] synonym: "capsule (sensu Fungi)" EXACT [] xref: GO:0030113 xref: GO:0042603 xref: GO:0042604 is_a: CCO:C0000959 ! glycocalyx [Term] id: CCO:C0001668 name: MHC protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0781735149 "Fundamental Immunology", PMID:15928678, PMID:16153240] subset: goslim_pir xref: GO:0042611 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001669 name: MHC class I protein complex namespace: cellular_component def: "A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules." [GOC:add, GOC:jl, ISBN:0120781859, ISBN:0781735149 "Fundamental Immunology"] comment: See also the cellular component term 'MHC class I peptide loading complex ; GO:0042824'. xref: GO:0042612 is_a: CCO:C0001668 ! MHC protein complex relationship: location_of CCO:B0020481 ! RET1G_HUMAN relationship: location_of CCO:B0020491 ! N2DL3_HUMAN relationship: location_of CCO:B0056199 ! MICB_HUMAN relationship: location_of CCO:B0056200 ! MICA_HUMAN relationship: location_of CCO:B0071946 ! ZA2G_HUMAN-Pyrrolidone carboxylic acid18 [Term] id: CCO:C0001670 name: MHC class II protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0120781859, PMID:15928678] xref: GO:0042613 is_a: CCO:C0001668 ! MHC protein complex relationship: location_of CCO:B0054858 ! 2B32_HUMAN relationship: location_of CCO:B0055019 ! 2B14_HUMAN relationship: location_of CCO:B0063248 ! HA25_HUMAN relationship: location_of CCO:B0063249 ! HB25_HUMAN relationship: location_of CCO:B0063340 ! 2DRA_HUMAN [Term] id: CCO:C0001671 name: photoreceptor outer segment membrane namespace: cellular_component def: "The membrane surrounding the outer segment of a vertebrate photoreceptor." [GOC:jl] xref: GO:0042622 is_a: CCO:C0000766 ! membrane is_a: CCO:C0001860 ! cilium part relationship: part_of CCO:C0000185 ! photoreceptor outer segment [Term] id: CCO:C0001672 name: chylomicron namespace: cellular_component def: "A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues." [GOC:jl, GOC:rl, http://biotech.icmb.utexas.edu/search/dict-search.html, http://cancerweb.ncl.ac.uk/] xref: GO:0042627 is_a: CCO:C0002138 ! plasma lipoprotein particle relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054863 ! APOA2_HUMAN relationship: location_of CCO:B0054864 ! APOC3_HUMAN relationship: location_of CCO:B0054871 ! APOH_HUMAN relationship: location_of CCO:B0056927 ! APOA5_HUMAN relationship: location_of CCO:B0063443 ! LIPL_HUMAN [Term] id: CCO:C0001673 name: mast cell granule namespace: cellular_component def: "Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase." [GOC:jl, http://cancerweb.ncl.ac.uk/, http://www.ijp-online.com/archives/1969/001/02/r0000-0000tc.htm, PMID:12360215] xref: GO:0042629 is_a: CCO:C0000347 ! lysosome relationship: location_of CCO:B0064598 ! CXCR2_HUMAN-Phosphoserine351 [Term] id: CCO:C0001674 name: actomyosin namespace: cellular_component def: "Any complex of actin, myosin, and accessory proteins." [GOC:go_curators] xref: GO:0042641 is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0064879 ! DREB_HUMAN-Phosphothreonine331 relationship: part_of CCO:C0000753 ! actin cytoskeleton [Term] id: CCO:C0001675 name: actomyosin, myosin complex part namespace: cellular_component def: "The myosin part of any complex of actin, myosin, and accessory proteins." [GOC:go_curators] xref: GO:0042642 is_a: CCO:C0000788 ! myosin complex relationship: part_of CCO:C0001674 ! actomyosin [Term] id: CCO:C0001676 name: actomyosin, actin part namespace: cellular_component def: "The actin part of any complex of actin, myosin, and accessory proteins." [GOC:go_curators] xref: GO:0042643 is_a: CCO:C0000442 ! actin filament relationship: location_of CCO:B0015638 ! ACTC_HUMAN relationship: part_of CCO:C0001674 ! actomyosin [Term] id: CCO:C0001677 name: chloroplast nucleoid namespace: cellular_component def: "The region of a chloroplast to which the DNA is confined." [GOC:jl] xref: GO:0042644 is_a: CCO:C0001679 ! plastid nucleoid is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000681 ! chloroplast stroma [Term] id: CCO:C0001678 name: mitochondrial nucleoid namespace: cellular_component def: "The region of a mitochondrion to which the DNA is confined." [GOC:jl] xref: GO:0042645 is_a: CCO:C0000563 ! nucleoid is_a: CCO:C0001848 ! mitochondrial part relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0001679 name: plastid nucleoid namespace: cellular_component def: "The region of a plastid to which the DNA is confined." [GOC:jl] xref: GO:0042646 is_a: CCO:C0000563 ! nucleoid is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000660 ! plastid stroma [Term] id: CCO:C0001680 name: proplastid nucleoid namespace: cellular_component def: "The region of a proplastid to which the DNA is confined." [GOC:jl] xref: GO:0042647 is_a: CCO:C0001679 ! plastid nucleoid relationship: part_of CCO:C0000682 ! proplastid stroma [Term] id: CCO:C0001681 name: chloroplast chromosome namespace: cellular_component def: "A circular DNA molecule containing chloroplast encoded genes." [GOC:jl] xref: GO:0042648 is_a: CCO:C0000637 ! plastid chromosome is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0001677 ! chloroplast nucleoid [Term] id: CCO:C0001682 name: prothylakoid namespace: cellular_component def: "Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light." [GOC:jl, PMID:11532175] xref: GO:0042649 is_a: CCO:C0001368 ! plastid thylakoid relationship: part_of CCO:C0000642 ! etioplast [Term] id: CCO:C0001683 name: prothylakoid membrane namespace: cellular_component def: "The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes." [GOC:jl, PMID:11532175] xref: GO:0042650 is_a: CCO:C0002020 ! plastid thylakoid membrane relationship: part_of CCO:C0001682 ! prothylakoid [Term] id: CCO:C0001684 name: thylakoid membrane namespace: cellular_component def: "The pigmented membrane of any thylakoid." [GOC:jl] subset: gosubset_prok xref: GO:0042651 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001855 ! thylakoid part [Term] id: CCO:C0001685 name: mitochondrial respiratory chain complex I, peripheral segment namespace: cellular_component def: "The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix." [GOC:jic, GOC:mtg_sensu, ISBN:0716749556] synonym: "NADH dehydrogenase (ubiquinone) complex, peripheral segment (sensu Eukaryota)" EXACT [] synonym: "NADH-Q oxidoreductase complex, peripheral segment (sensu Eukaryota)" EXACT [] synonym: "respiratory chain complex I, peripheral segment (sensu Eukaryota)" EXACT [] xref: GO:0042652 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000333 ! mitochondrial respiratory chain complex I [Term] id: CCO:C0001686 name: mitochondrial respiratory chain complex I, membrane segment namespace: cellular_component def: "The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix." [GOC:jic, GOC:mtg_sensu, ISBN:0716749556] synonym: "NADH-Q oxidoreductase complex, membrane segment (sensu Eukaryota)" EXACT [] synonym: "respiratory chain complex I, membrane segment (sensu Eukaryota)" EXACT [] xref: GO:0042653 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000333 ! mitochondrial respiratory chain complex I [Term] id: CCO:C0001687 name: succinate-CoA ligase complex namespace: cellular_component def: "A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP." [EC:6.2.1.4, EC:6.2.1.5, GOC:jl] subset: gosubset_prok xref: GO:0042709 is_a: CCO:C0001903 ! tricarboxylic acid cycle enzyme complex [Term] id: CCO:C0001688 name: chromatophore namespace: cellular_component def: "A pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria which is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle." [GOC:jl, ISBN:0395825172, PMID:11867431] comment: Note that this structure is distinct from the chromoplast of plants, which is also sometimes called a chromatophore; it also should not be confused with the specialized pigment-producing cells known as chromatophores, found in fish and amphibian skin. subset: gosubset_prok synonym: "chromatophore vesicle" EXACT [] synonym: "thylakoid (sensu Bacteria)" RELATED [] synonym: "thylakoid (sensu Proteobacteria)" RELATED [] xref: GO:0042716 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001689 name: chromatophore membrane namespace: cellular_component def: "The lipid bilayer surrounding a chromatophore, a pigment-bearing vesicle found in certain photosynthetic bacteria and cyanobacteria." [GOC:jl, ISBN:0395825172, PMID:11867431] subset: gosubset_prok xref: GO:0042717 is_a: CCO:C0001024 ! cytoplasmic vesicle membrane is_a: CCO:C0001688 ! chromatophore [Term] id: CCO:C0001690 name: yolk granule namespace: cellular_component def: "Discrete structures that partition the yolk of oocytes and ova, which may or may not be membrane enclosed." [GOC:jl, http://148.216.10.83/cellbio/eggs.htm] xref: GO:0042718 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001691 name: mitochondrial intermembrane space protein transporter complex namespace: cellular_component def: "Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane." [PMID:12581629] synonym: "Tim9-Tim10 complex" NARROW [] xref: GO:0042719 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001848 ! mitochondrial part relationship: part_of CCO:C0000341 ! mitochondrial intermembrane space [Term] id: CCO:C0001692 name: mitochondrial inner membrane peptidase complex namespace: cellular_component def: "Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space." [PMID:10821182, PMID:12191769] synonym: "IMP" NARROW [] xref: GO:0042720 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0001693 name: mitochondrial inner membrane protein insertion complex namespace: cellular_component def: "A multi-subunit complex embedded in the mitochondrial inner membrane that mediates insertion of carrier proteins into the inner membrane." [PMID:12191765] synonym: "Tim22 complex" NARROW [] xref: GO:0042721 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001874 ! mitochondrial membrane part relationship: part_of CCO:C0000329 ! mitochondrial inner membrane [Term] id: CCO:C0001694 name: DASH complex namespace: cellular_component def: "A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complexes associate with kinetochores or microtubules and play a role spindle attachment, chromosome segregation and spindle stability." [GOC:jl, PMID:11782438, PMID:11799062] comment: Note that this complex is conserved in fungi but has not been observed in metazoans. synonym: "Dam1 complex" EXACT [] synonym: "DDD complex" EXACT [] synonym: "Duo1p-Dam1p-Dad1p complex" EXACT [] xref: GO:0042729 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0001695 name: presynaptic membrane namespace: cellular_component def: "A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0042734 is_a: CCO:C0000766 ! membrane is_a: CCO:C0001875 ! synapse part relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0023179 ! NPTN_HUMAN relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0042239 ! GRM2_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0069763 ! RB6I2_HUMAN-Phosphoserine17 relationship: location_of CCO:B0070678 ! SNCAP_HUMAN-Phosphothreonine387 [Term] id: CCO:C0001696 name: protein body namespace: cellular_component def: "A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins." [GOC:jl, PMID:7704047] xref: GO:0042735 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0001697 name: giant axon namespace: cellular_component def: "Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0042757 is_a: CCO:C0001004 ! axon [Term] id: CCO:C0001700 name: GPI-anchor transamidase complex namespace: cellular_component def: "An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxyl-terminus of a precursor protein to a GPI-anchor." [GOC:jl, GOC:rb, PMID:12802054] comment: Note that this term should not be confused with 'glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506', which represents a distinct complex with a different catalytic activity. synonym: "GPIT complex" EXACT [] xref: GO:0042765 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: location_of CCO:B0002135 ! PIGU_HUMAN relationship: location_of CCO:B0006273 ! GPAA1_HUMAN relationship: part_of CCO:C0000990 ! integral to endoplasmic reticulum membrane [Term] id: CCO:C0001701 name: polysomal ribosome namespace: cellular_component def: "A ribosome bound to mRNA that forms part of a polysome." [GOC:jl] synonym: "active ribosome" BROAD [] xref: GO:0042788 is_a: CCO:C0000407 ! ribosome relationship: location_of CCO:B0005761 ! RL7A_HUMAN relationship: location_of CCO:B0055483 ! NR0B1_HUMAN relationship: part_of CCO:C0000410 ! polysome [Term] id: CCO:C0001702 name: central vacuole namespace: cellular_component def: "A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination." [http://www.wikipedia.org/] xref: GO:0042807 is_a: CCO:C0002152 ! plant-type vacuole [Term] id: CCO:C0001703 name: MHC class I peptide loading complex namespace: cellular_component def: "A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules." [GOC:jl, PMID:10631934] comment: Note that although this complex is located in the endoplasmic reticulum, there is some evidence that it may also be found in the Golgi. subset: goslim_pir xref: GO:0042824 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001851 ! endoplasmic reticulum part [Term] id: CCO:C0001704 name: TAP complex namespace: cellular_component def: "A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum." [GOC:jl, PMID:10618487, PMID:10631934] synonym: "transporter associated with antigen presentation" EXACT [] xref: GO:0042825 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0001703 ! MHC class I peptide loading complex [Term] id: CCO:C0001705 name: platelet dense granule namespace: cellular_component def: "Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins." [GOC:jl, http://www.mercksource.com/, PMID:10403682, PMID:11487378] synonym: "bull's eye body" EXACT [] synonym: "platelet dense body" EXACT [] xref: GO:0042827 is_a: CCO:C0000985 ! secretory granule relationship: location_of CCO:B0066894 ! HPS4_HUMAN-Phosphoserine355 [Term] id: CCO:C0001706 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] subset: goslim_pir subset: gosubset_prok xref: GO:0042995 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0001479 ! ANXA1_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0002060 ! NEB2_HUMAN relationship: location_of CCO:B0002099 ! CP250_HUMAN relationship: location_of CCO:B0002150 ! PAR6A_HUMAN relationship: location_of CCO:B0002248 ! LZTS1_HUMAN relationship: location_of CCO:B0005306 ! MYOZ1_HUMAN relationship: location_of CCO:B0006172 ! ARPC3_HUMAN relationship: location_of CCO:B0006333 ! TTLL5_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0010875 ! CAC1A_HUMAN-Phosphoserine2030 relationship: location_of CCO:B0010926 ! CASL_HUMAN-Phosphotyrosine166 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0011809 ! EXOC8_HUMAN-Phosphoserine19 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0015018 ! PPIP1_HUMAN relationship: location_of CCO:B0024099 ! ARPC2_HUMAN relationship: location_of CCO:B0024597 ! CEND3_HUMAN relationship: location_of CCO:B0028186 ! ARP2_HUMAN relationship: location_of CCO:B0028914 ! AB1IP_HUMAN relationship: location_of CCO:B0033364 ! RUFY3_HUMAN relationship: location_of CCO:B0034567 ! ARP3_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0035712 ! STMN2_HUMAN-Phosphoserine16 relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0038095 ! ABI2_HUMAN relationship: location_of CCO:B0038991 ! CSTN1_HUMAN relationship: location_of CCO:B0039483 ! KI18A_HUMAN-Phosphoserine357 relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0050612 ! NCKP1_HUMAN relationship: location_of CCO:B0054441 ! ARPC5_HUMAN relationship: location_of CCO:B0054609 ! NPHP4_HUMAN relationship: location_of CCO:B0054636 ! USH2A_HUMAN relationship: location_of CCO:B0054817 ! GAS8_HUMAN relationship: location_of CCO:B0055823 ! DYH14_HUMAN relationship: location_of CCO:B0057092 ! RAPH1_HUMAN relationship: location_of CCO:B0057113 ! RHOU_HUMAN relationship: location_of CCO:B0057306 ! PDPN_HUMAN relationship: location_of CCO:B0057343 ! TIAM2_HUMAN relationship: location_of CCO:B0057438 ! RHG24_HUMAN relationship: location_of CCO:B0057591 ! NGDN_HUMAN relationship: location_of CCO:B0058028 ! DYH12_HUMAN relationship: location_of CCO:B0058195 ! SGEF_HUMAN relationship: location_of CCO:B0058282 ! FGD4_HUMAN relationship: location_of CCO:B0058936 ! IFT57_HUMAN relationship: location_of CCO:B0059177 ! DBNL_HUMAN relationship: location_of CCO:B0062879 ! CTSR1_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063364 ! ARPC4_HUMAN relationship: location_of CCO:B0063370 ! SRC8_HUMAN relationship: location_of CCO:B0063410 ! MYO15_HUMAN relationship: location_of CCO:B0063711 ! BAIP2_HUMAN-Phosphothreonine296 relationship: location_of CCO:B0064039 ! CABYR_HUMAN-Phosphoserine362 relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0064229 ! CDGAP_HUMAN-Phosphoserine1106 relationship: location_of CCO:B0064449 ! CPEB1_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0064565 ! CSPG4_HUMAN-Phosphothreonine21 relationship: location_of CCO:B0064831 ! DOCK7_HUMAN-Phosphoserine1432 relationship: location_of CCO:B0064874 ! DPYL3_HUMAN-Phosphoserine551 relationship: location_of CCO:B0065046 ! EM55_HUMAN-Phosphoserine19 relationship: location_of CCO:B0065175 ! EVL_HUMAN-Phosphoserine306 relationship: location_of CCO:B0065551 ! AKAP4_HUMAN-Phosphoserine492 relationship: location_of CCO:B0065818 ! CAPR1_HUMAN-Phosphoserine611 relationship: location_of CCO:B0066177 ! FGD1_HUMAN-Phosphothreonine711 relationship: location_of CCO:B0066589 ! GRDN_HUMAN-Phosphoserine1387 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068580 ! NEUM_HUMAN-Phosphoserine41 relationship: location_of CCO:B0068704 ! NGEF_HUMAN-Phosphotyrosine179 relationship: location_of CCO:B0068709 ! NHERF_HUMAN-Phosphoserine288 relationship: location_of CCO:B0068828 ! NRBP_HUMAN-Phosphothreonine441 relationship: location_of CCO:B0069412 ! PLEK2_HUMAN-Phosphotyrosine333 relationship: location_of CCO:B0069705 ! RAC3_HUMAN-Cysteine methyl ester189 relationship: location_of CCO:B0070843 ! SPY4_HUMAN-Phosphoserine125 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: location_of CCO:B0071778 ! VASP_HUMAN-Phosphotyrosine39 relationship: location_of CCO:B0071823 ! WASF2_HUMAN-Phosphoserine482 [Term] id: CCO:C0001707 name: neuron projection namespace: cellular_component def: "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] subset: goslim_pir synonym: "neurite" NARROW [] synonym: "neuronal cell projection" EXACT [] xref: GO:0043005 is_a: CCO:C0001706 ! cell projection relationship: location_of CCO:B0005599 ! KINH_HUMAN relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0006166 ! KIF5A_HUMAN relationship: location_of CCO:B0012776 ! MARK4_HUMAN-Phosphoserine26 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035307 ! NRCAM_HUMAN-Phosphoserine427 relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0055534 ! CAD13_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0058105 ! GHSR_HUMAN relationship: location_of CCO:B0064831 ! DOCK7_HUMAN-Phosphoserine1432 relationship: location_of CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 relationship: location_of CCO:B0071730 ! ULK1_HUMAN-Phosphothreonine625 [Term] id: CCO:C0001708 name: NADPH oxidase complex namespace: cellular_component def: "A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2." [GOC:jl, PMID:11483596, PMID:12440767] synonym: "flavocytochrome b558" NARROW [] synonym: "respiratory-burst oxidase" RELATED [] xref: GO:0043020 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0057254 ! NOXA1_HUMAN relationship: location_of CCO:B0057598 ! NOXO1_HUMAN relationship: location_of CCO:B0059386 ! NOX1_HUMAN relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001709 name: cell soma namespace: cellular_component def: "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." [GOC:go_curators] comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. subset: goslim_pir synonym: "cell body" EXACT [] xref: GO:0043025 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0001687 ! TGFB2_HUMAN relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0005739 ! GBLP_HUMAN relationship: location_of CCO:B0005816 ! ATX10_HUMAN relationship: location_of CCO:B0010528 ! ANGI_HUMAN-Pyrrolidone carboxylic acid25 relationship: location_of CCO:B0011115 ! CDK5_HUMAN-Phosphoserine159 relationship: location_of CCO:B0013325 ! NUMA1_HUMAN-Phosphoserine2077 relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0054845 ! CALC_HUMAN relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0058468 ! DPYL5_HUMAN relationship: location_of CCO:B0064792 ! DNER_HUMAN-Phosphotyrosine718 relationship: location_of CCO:B0064869 ! DPYL2_HUMAN-Phosphoserine518 relationship: location_of CCO:B0066979 ! IAPP_HUMAN-Tyrosine amide70 relationship: location_of CCO:B0070613 ! SMBP2_HUMAN-Phosphoserine656 relationship: location_of CCO:B0070678 ! SNCAP_HUMAN-Phosphothreonine387 [Term] id: CCO:C0001710 name: isoamylase complex namespace: cellular_component def: "A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages." [GOC:jl, PMID:10333591] subset: goslim_pir subset: gosubset_prok synonym: "debranching enzyme complex" BROAD [] xref: GO:0043033 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0066433 ! GDE_HUMAN-Phosphotyrosine584 [Term] id: CCO:C0001711 name: costamere namespace: cellular_component def: "Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix." [GOC:jl, GOC:mtg_muscle, http://cancerweb.ncl.ac.uk/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:6405378] xref: GO:0043034 is_a: CCO:C0001868 ! contractile fiber part relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0071018 ! SVIL_HUMAN-Phosphoserine1052 relationship: part_of CCO:C0000932 ! myofibril [Term] id: CCO:C0001712 name: starch grain namespace: cellular_component def: "Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped." [GOC:jl, PMID:11217978] synonym: "starch granule" EXACT [] xref: GO:0043036 is_a: CCO:C0001854 ! plastid part [Term] id: CCO:C0001713 name: germ cell nucleus namespace: cellular_component def: "The nucleus of a germ cell, a cell specialized to produce haploid gametes, and its descendents." [GOC:go_curators, http://cancerweb.ncl.ac.uk] synonym: "germ-cell nucleus" EXACT [] xref: GO:0043073 is_a: CCO:C0000252 ! nucleus [Term] id: CCO:C0001714 name: megasporocyte nucleus namespace: cellular_component def: "The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents." [GOC:jl, ISBN:0618254153] synonym: "megaspore mother cell nucleus" EXACT [] xref: GO:0043076 is_a: CCO:C0000252 ! nucleus [Term] id: CCO:C0001715 name: polar nucleus namespace: cellular_component def: "Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus." [ISBN:0618254153] xref: GO:0043078 is_a: CCO:C0001714 ! megasporocyte nucleus [Term] id: CCO:C0001716 name: antipodal cell nucleus namespace: cellular_component def: "The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents." [GOC:jl, http://cancerweb.ncl.ac.uk] xref: GO:0043079 is_a: CCO:C0001714 ! megasporocyte nucleus [Term] id: CCO:C0001717 name: megagametophyte egg cell nucleus namespace: cellular_component def: "The nucleus of a plant egg cell, the female gamete, at the micropylar end of the embryo and its descendents." [GOC:jl, GOC:mtg_sensu] synonym: "egg cell nucleus (sensu Viridiplantae)" EXACT [] xref: GO:0043082 is_a: CCO:C0001714 ! megasporocyte nucleus [Term] id: CCO:C0001718 name: synaptic cleft namespace: cellular_component def: "The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released." [GOC:jl, http://synapses.mcg.edu/anatomy/chemical/synapse.stm] xref: GO:0043083 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001875 ! synapse part [Term] id: CCO:C0001719 name: acrosomal matrix namespace: cellular_component def: "A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction." [GOC:jl, PMID:8949900, PMID:9139729] xref: GO:0043159 is_a: CCO:C0001856 ! vacuolar part relationship: part_of CCO:C0000177 ! acrosome [Term] id: CCO:C0001720 name: acrosomal lumen namespace: cellular_component def: "The volume enclosed within the acrosome membrane." [GOC:go_curators] xref: GO:0043160 is_a: CCO:C0001731 ! lysosomal lumen relationship: part_of CCO:C0000177 ! acrosome [Term] id: CCO:C0001721 name: P granule namespace: cellular_component def: "A small protein and RNA containing electron dense organelle, not surrounded by a membrane, that is associated with germ nuclei in the gonad and localized to germ cells and their precursors throughout development." [GOC:kva, PMID:11262230] xref: GO:0043186 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle relationship: part_of CCO:C0001952 ! pole plasm [Term] id: CCO:C0001722 name: cell septum surface namespace: cellular_component def: "The extracellular (rather than the intracellular) exterior of a dividing septum; this surface is usually composed of cell wall material, for example, lineal (1,3)-beta-D-glucan in S. pombe." [GOC:go_curators] synonym: "septum surface" BROAD [] xref: GO:0043187 is_a: CCO:C0001876 ! cell septum part [Term] id: CCO:C0001723 name: cell septum edging namespace: cellular_component def: "The cell wall material that surrounds the septum in fungal cells." [GOC:vw] synonym: "septum edging" BROAD [] synonym: "septum edging (sensu Fungi)" EXACT [] xref: GO:0043188 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0002066 ! fungal-type cell wall [Term] id: CCO:C0001724 name: H4/H2A histone acetyltransferase complex namespace: cellular_component def: "A multisubunit complex that catalyzes the acetylation of histones H4 and H2A." [GOC:mah] synonym: "H4/H2A HAT complex" EXACT [] xref: GO:0043189 is_a: CCO:C0000011 ! histone acetyltransferase complex relationship: location_of CCO:B0068287 ! MRGBP_HUMAN-Phosphoserine191 [Term] id: CCO:C0001725 name: ATP-binding cassette (ABC) transporter complex namespace: cellular_component def: "A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter." [GOC:jl, GOC:mtg_sensu, PMID:11421269, PMID:15111107] subset: goslim_pir subset: gosubset_prok synonym: "ABC-type efflux permease activity" NARROW [] synonym: "ABC-type efflux porter activity" NARROW [] synonym: "ABC-type uptake permease activity" NARROW [] synonym: "ATP-binding cassette (ABC) transporter activity" RELATED [] synonym: "ATP-binding cassette (ABC) transporter complex (sensu Bacteria and Archaea)" EXACT [] synonym: "ATP-binding cassette (ABC) transporter complex (sensu Eukaryota)" EXACT [] synonym: "mating pheromone exporter" NARROW [] xref: GO:0043190 xref: GO:0043191 xref: GO:0043192 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0006268 ! ABCD4_HUMAN relationship: location_of CCO:B0065266 ! ABCA2_HUMAN-Phosphoserine1331 [Term] id: CCO:C0001726 name: initial segment namespace: cellular_component def: "Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment." [GOC:nln] xref: GO:0043194 is_a: CCO:C0001562 ! axon part [Term] id: CCO:C0001727 name: terminal button namespace: cellular_component def: "Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters." [GOC:nln] synonym: "bouton" EXACT [] synonym: "presynaptic bouton" EXACT [] synonym: "synaptic bouton" EXACT [] xref: GO:0043195 is_a: CCO:C0001562 ! axon part relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0054845 ! CALC_HUMAN relationship: location_of CCO:B0055564 ! CABP4_HUMAN relationship: location_of CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 [Term] id: CCO:C0001728 name: varicosity namespace: cellular_component def: "Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters." [GOC:nln] xref: GO:0043196 is_a: CCO:C0001562 ! axon part [Term] id: CCO:C0001729 name: dendritic spine namespace: cellular_component def: "Protrusion from a dendrite. Spines are specialised subcellular compartments involved in the synaptic transmission. They are linked to the dendritic shaft by a restriction. Because of their bulb shape, they function as a biochemical and an electrical compartment. Spine remodeling is though to be involved in synaptic plasticity." [GOC:nln] xref: GO:0043197 is_a: CCO:C0001881 ! cell projection part relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0005642 ! ACTN2_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: part_of CCO:C0001005 ! dendrite [Term] id: CCO:C0001730 name: dendritic shaft namespace: cellular_component def: "Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines." [GOC:nln] xref: GO:0043198 is_a: CCO:C0001881 ! cell projection part relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: part_of CCO:C0001005 ! dendrite [Term] id: CCO:C0001731 name: lysosomal lumen namespace: cellular_component def: "The volume enclosed within the lysosomal membrane." [GOC:jl, PMID:15213228] xref: GO:0043202 is_a: CCO:C0000357 ! vacuolar lumen relationship: part_of CCO:C0000347 ! lysosome [Term] id: CCO:C0001732 name: axon hillock namespace: cellular_component def: "Portion of the neuronal cell soma from which the axon originates." [GOC:nln] xref: GO:0043203 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0001709 ! cell soma [Term] id: CCO:C0001733 name: perikaryon namespace: cellular_component def: "The portion of the cell soma (cell body) that excludes the nucleus." [GOC:jl] synonym: "cell soma cytoplasm" RELATED [] xref: GO:0043204 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0002075 ! NECD_HUMAN relationship: location_of CCO:B0005652 ! ESR1_HUMAN relationship: part_of CCO:C0001709 ! cell soma [Term] id: CCO:C0001734 name: fibril namespace: cellular_component def: "Extracellular matrix material consisting of polysaccharides and protein." [PMID:12704238] xref: GO:0043205 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000203 ! proteinaceous extracellular matrix [Term] id: CCO:C0001735 name: myelin sheath namespace: cellular_component def: "An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system." [GOC:jl, http://en.wikipedia.org/] xref: GO:0043209 is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0035174 ! MBP_HUMAN-Phosphoserine205 [Term] id: CCO:C0001736 name: compact myelin namespace: cellular_component def: "The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs." [GOC:dgh] xref: GO:0043218 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0001735 ! myelin sheath [Term] id: CCO:C0001737 name: lateral loop namespace: cellular_component def: "Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode." [GOC:dgh] xref: GO:0043219 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0001735 ! myelin sheath [Term] id: CCO:C0001738 name: Schmidt-Lanterman cleft namespace: cellular_component def: "Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman clefts occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier." [GOC:dgh] xref: GO:0043220 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0001735 ! myelin sheath [Term] id: CCO:C0001739 name: SMC/kleisin ring complex namespace: cellular_component def: "A molecular ring complex composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1 and Smc3, and the kleisin protein Scc1." [GOC:jl, PMID:12667442] xref: GO:0043222 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0000120 ! condensed chromosome [Term] id: CCO:C0001740 name: cytoplasmic SCF ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063] synonym: "cytoplasmic cullin complex" EXACT [] synonym: "cytoplasmic SCF complex" EXACT [] synonym: "cytoplasmic Skp1/Cul1/F-box protein complex" EXACT [] xref: GO:0043223 is_a: CCO:C0000028 ! cytoplasmic ubiquitin ligase complex is_a: CCO:C0000850 ! SCF ubiquitin ligase complex [Term] id: CCO:C0001741 name: nuclear SCF ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063] synonym: "nuclear cullin complex" EXACT [] synonym: "nuclear SCF complex" EXACT [] synonym: "nuclear Skp1/Cul1/F-box protein complex" EXACT [] xref: GO:0043224 is_a: CCO:C0000027 ! nuclear ubiquitin ligase complex is_a: CCO:C0000850 ! SCF ubiquitin ligase complex [Term] id: CCO:C0001742 name: organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_generic subset: goslim_pir subset: gosubset_prok xref: GO:0043226 is_a: CCO:C0000200 ! cellular_component [Term] id: CCO:C0001745 name: intracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir subset: gosubset_prok xref: GO:0043229 is_a: CCO:C0001742 ! organelle is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0058605 ! B2L14_HUMAN [Term] id: CCO:C0001746 name: extracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." [GOC:jl, PMID:9914479] subset: goslim_pir subset: gosubset_prok xref: GO:0043230 is_a: CCO:C0001742 ! organelle is_a: CCO:C0001840 ! extracellular region part [Term] id: CCO:C0001749 name: organelle lumen namespace: cellular_component def: "The volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear membrane lumen." [GOC:jl] xref: GO:0043233 is_a: CCO:C0001366 ! membrane-enclosed lumen is_a: CCO:C0001841 ! organelle part [Term] id: CCO:C0001750 name: protein complex namespace: cellular_component def: "Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or carbohydrate groups." [GOC:go_curators] comment: Note that although at some level almost all cellular components can be thought of as protein complexes, this term is intended to exclude structures composed of the same repeating subunit or subunits, for example microtubules. Protein complexes encompassed by this term are generally not structural, and usually have a defined set of subunits. subset: goslim_generic subset: goslim_pir subset: gosubset_prok synonym: "protein-protein complex" EXACT [] xref: GO:0043234 is_a: CCO:C0001492 ! macromolecular complex relationship: location_of CCO:B0001397 ! ACTN4_HUMAN relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0001548 ! TBG1_HUMAN relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0001625 ! PSMD8_HUMAN relationship: location_of CCO:B0001649 ! BRCA2_HUMAN relationship: location_of CCO:B0001745 ! PSMD2_HUMAN relationship: location_of CCO:B0001754 ! TBB3_HUMAN relationship: location_of CCO:B0001769 ! TBB2A_HUMAN relationship: location_of CCO:B0002066 ! PSMD1_HUMAN relationship: location_of CCO:B0002211 ! TBE_HUMAN relationship: location_of CCO:B0005181 ! UBQL1_HUMAN relationship: location_of CCO:B0005233 ! PSA1_HUMAN relationship: location_of CCO:B0005298 ! KAP0_HUMAN relationship: location_of CCO:B0005442 ! FBX7_HUMAN relationship: location_of CCO:B0005571 ! BAT5_HUMAN relationship: location_of CCO:B0005586 ! DSS1_HUMAN relationship: location_of CCO:B0006167 ! TBB4_HUMAN relationship: location_of CCO:B0006215 ! PSME1_HUMAN relationship: location_of CCO:B0006219 ! PSB10_HUMAN relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0010825 ! BOREA_HUMAN-Phosphoserine219 relationship: location_of CCO:B0010853 ! BRCA1_HUMAN-Phosphoserine1423 relationship: location_of CCO:B0011457 ! DDB2_HUMAN-Phosphoserine24 relationship: location_of CCO:B0012199 ! HNF1A_HUMAN-Phosphothreonine74 relationship: location_of CCO:B0012399 ! INCE_HUMAN-Phosphoserine296 relationship: location_of CCO:B0013498 ! PGH2_HUMAN-Phosphoserine437 relationship: location_of CCO:B0013617 ! PRS4_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0013620 ! PSA3_HUMAN-Phosphotyrosine161 relationship: location_of CCO:B0014308 ! TBA1A_HUMAN-Phosphoserine6 relationship: location_of CCO:B0014311 ! TBA1B_HUMAN-Phosphotyrosine272 relationship: location_of CCO:B0014317 ! TBB5_HUMAN-Phosphotyrosine36 relationship: location_of CCO:B0014540 ! TSC1_HUMAN-Phosphoserine505 relationship: location_of CCO:B0014564 ! UBE3A_HUMAN-Phosphoserine218 relationship: location_of CCO:B0014899 ! IPSP_HUMAN relationship: location_of CCO:B0019877 ! Q7KZS6_HUMAN relationship: location_of CCO:B0021560 ! PSMD3_HUMAN relationship: location_of CCO:B0022204 ! PSA5_HUMAN relationship: location_of CCO:B0023606 ! PSDE_HUMAN relationship: location_of CCO:B0024576 ! TBA3C_HUMAN relationship: location_of CCO:B0024578 ! TBA8_HUMAN relationship: location_of CCO:B0030804 ! PSB8_HUMAN relationship: location_of CCO:B0030806 ! PSB5_HUMAN relationship: location_of CCO:B0030810 ! Q5JNW7_HUMAN relationship: location_of CCO:B0030929 ! PSB3_HUMAN relationship: location_of CCO:B0031007 ! PSB9_HUMAN relationship: location_of CCO:B0031015 ! PSB6_HUMAN relationship: location_of CCO:B0031378 ! TBB2B_HUMAN-Phosphotyrosine36 relationship: location_of CCO:B0032651 ! PSMD6_HUMAN relationship: location_of CCO:B0033014 ! SODC_HUMAN relationship: location_of CCO:B0034007 ! PSB7_HUMAN relationship: location_of CCO:B0035234 ! MYH9_HUMAN-Phosphothreonine181 relationship: location_of CCO:B0035477 ! PSA7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0035478 ! PSB1_HUMAN-Phosphotyrosine150 relationship: location_of CCO:B0035479 ! PSB2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035483 ! PSD7_HUMAN-Phosphothreonine186 relationship: location_of CCO:B0035539 ! RD23B_HUMAN-Phosphoserine160 relationship: location_of CCO:B0036013 ! MEN1_HUMAN-Phosphoserine399 relationship: location_of CCO:B0039597 ! PRS10_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0039598 ! PSD12_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041126 ! BCL3_HUMAN-Phosphoserine394 relationship: location_of CCO:B0041206 ! TBA4A_HUMAN-Phosphotyrosine440 relationship: location_of CCO:B0041239 ! PSMD9_HUMAN relationship: location_of CCO:B0041243 ! PSA2_HUMAN relationship: location_of CCO:B0041244 ! PSA4_HUMAN relationship: location_of CCO:B0041245 ! PSB4_HUMAN relationship: location_of CCO:B0041246 ! PRS7_HUMAN relationship: location_of CCO:B0041247 ! PRS6B_HUMAN relationship: location_of CCO:B0041251 ! PSA6_HUMAN relationship: location_of CCO:B0041252 ! PSME3_HUMAN relationship: location_of CCO:B0041253 ! PRS8_HUMAN relationship: location_of CCO:B0041255 ! PSMD5_HUMAN relationship: location_of CCO:B0041315 ! PRS6A_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041328 ! PSD10_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041333 ! PSMD4_HUMAN-Phosphoserine358 relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: location_of CCO:B0052858 ! TOP2A_HUMAN-Phosphoserine1504 relationship: location_of CCO:B0054309 ! CLIC1_HUMAN relationship: location_of CCO:B0054801 ! DDAH2_HUMAN relationship: location_of CCO:B0054874 ! ALBU_HUMAN relationship: location_of CCO:B0055155 ! S10A1_HUMAN relationship: location_of CCO:B0055887 ! ERCC8_HUMAN relationship: location_of CCO:B0057244 ! LDB1_HUMAN relationship: location_of CCO:B0058606 ! FOXP3_HUMAN relationship: location_of CCO:B0059106 ! MALT1_HUMAN relationship: location_of CCO:B0063064 ! TBA4B_HUMAN relationship: location_of CCO:B0063110 ! Q8N532_HUMAN relationship: location_of CCO:B0063270 ! DZIP1_HUMAN relationship: location_of CCO:B0063416 ! CC113_HUMAN relationship: location_of CCO:B0065610 ! ALS2_HUMAN-Phosphothreonine1344 relationship: location_of CCO:B0067849 ! MAGD1_HUMAN-Phosphotyrosine92 relationship: location_of CCO:B0069579 ! PSMF1_HUMAN-Phosphoserine252 relationship: location_of CCO:B0070827 ! SPTB1_HUMAN-Phosphoserine2117 relationship: location_of CCO:B0071118 ! TAL1_HUMAN-Phosphoserine122 relationship: location_of CCO:B0071208 ! TBB2C_HUMAN-Phosphoserine322 relationship: location_of CCO:B0071574 ! TRIPC_HUMAN-Phosphoserine997 [Term] id: CCO:C0001751 name: receptor complex namespace: cellular_component def: "Any protein group composed of two or more subunits, which may or may not be identical, which undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:go_curators] subset: goslim_pir subset: gosubset_prok xref: GO:0043235 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0014349 ! TGFR2_HUMAN-Phosphoserine548 relationship: location_of CCO:B0020371 ! BMR1B_HUMAN relationship: location_of CCO:B0039677 ! TGFR1_HUMAN-Phosphoserine191 relationship: location_of CCO:B0048254 ! ERBB3_HUMAN-Phosphotyrosine1328 relationship: location_of CCO:B0055020 ! ADRB3_HUMAN relationship: location_of CCO:B0065103 ! ERBB2_HUMAN-Phosphotyrosine735 relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: location_of CCO:B0070602 ! SMAD3_HUMAN-Phosphoserine416 [Term] id: CCO:C0001752 name: Fanconi anaemia nuclear complex namespace: cellular_component def: "A protein complex composed of the Fanconi anaemia (FA) proteins A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage." [GOC:jl, PMID:12093742] synonym: "FA complex" EXACT [] synonym: "FA nuclear complex" EXACT [] synonym: "Fanconi anaemia complex" EXACT [] xref: GO:0043240 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001870 ! nucleoplasm part [Term] id: CCO:C0001753 name: extraorganismal space namespace: cellular_component def: "The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms." [GOC:jl] subset: gosubset_prok xref: GO:0043245 is_a: CCO:C0001840 ! extracellular region part [Term] id: CCO:C0001754 name: megasome namespace: cellular_component def: "Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex." [http://cancerweb.ncl.ac.uk/, PMID:11206117, PMID:1999020] xref: GO:0043246 is_a: CCO:C0000347 ! lysosome [Term] id: CCO:C0001755 name: chloroplast ribosome namespace: cellular_component def: "A ribosome contained within a chloroplast." [GOC:ecd] xref: GO:0043253 is_a: CCO:C0000674 ! plastid ribosome is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000681 ! chloroplast stroma [Term] id: CCO:C0001756 name: laminin complex namespace: cellular_component def: "A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes." [GOC:jl, http://www.sdbonline.org/fly/newgene/laminna1.htm, PMID:10842354] subset: goslim_pir xref: GO:0043256 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000228 ! basal lamina [Term] id: CCO:C0001757 name: laminin-8 complex namespace: cellular_component def: "A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0043257 is_a: CCO:C0001756 ! laminin complex relationship: location_of CCO:B0005967 ! LAMB1_HUMAN [Term] id: CCO:C0001758 name: laminin-9 complex namespace: cellular_component def: "A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0043258 is_a: CCO:C0001756 ! laminin complex [Term] id: CCO:C0001759 name: laminin-10 complex namespace: cellular_component def: "A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0043259 is_a: CCO:C0001756 ! laminin complex relationship: location_of CCO:B0005967 ! LAMB1_HUMAN relationship: location_of CCO:B0054985 ! LAMC1_HUMAN [Term] id: CCO:C0001760 name: laminin-11 complex namespace: cellular_component def: "A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0043260 is_a: CCO:C0001756 ! laminin complex [Term] id: CCO:C0001761 name: laminin-12 complex namespace: cellular_component def: "A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains." [GOC:jl, PMID:10842354] xref: GO:0043261 is_a: CCO:C0001756 ! laminin complex [Term] id: CCO:C0001762 name: cellulosome namespace: cellular_component def: "An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose." [GOC:jl, PMID:11601609] subset: gosubset_prok xref: GO:0043263 is_a: CCO:C0002131 ! extracellular non-membrane-bounded organelle [Term] id: CCO:C0001764 name: ectoplasm namespace: cellular_component def: "Granule free cytoplasm, lying immediately below the plasma membrane." [http://cancerweb.ncl.ac.uk/] xref: GO:0043265 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001765 name: RAVE complex namespace: cellular_component def: "A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme." [PMID:11283612, PMID:11844802] synonym: "regulator of the (H+)-ATPase of the vacuolar and endosomal membranes" BROAD [] xref: GO:0043291 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001766 name: contractile fiber namespace: cellular_component def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194] synonym: "contractile fibre" EXACT [] synonym: "muscle fiber" BROAD [] synonym: "muscle fibre" BROAD [] xref: GO:0043292 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0001802 ! CD5R1_HUMAN relationship: location_of CCO:B0058137 ! TRI63_HUMAN [Term] id: CCO:C0001767 name: apoptosome namespace: cellular_component def: "A multisubunit protein complex involved in the activation of apoptosis. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms." [PMID:10428850, PMID:11406413, PMID:12176339, PMID:15189137] xref: GO:0043293 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part [Term] id: CCO:C0001768 name: mitochondrial glutamate synthase complex (NADH) namespace: cellular_component def: "A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity." [GOC:jl, PMID:7047525] xref: GO:0043294 is_a: CCO:C0001115 ! glutamate synthase complex (NADH) is_a: CCO:C0001848 ! mitochondrial part relationship: part_of CCO:C0000342 ! mitochondrial matrix [Term] id: CCO:C0001769 name: apical junction complex namespace: cellular_component def: "A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in invertebrates is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." [GOC:go_curators, PMID:12525486, PMID:15196556] xref: GO:0043296 is_a: CCO:C0000463 ! intercellular junction relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0014759 ! ZO1_HUMAN-Phosphoserine337 relationship: location_of CCO:B0070515 ! SHRM3_HUMAN-Phosphoserine584 relationship: part_of CCO:C0000782 ! apicolateral plasma membrane [Term] id: CCO:C0001770 name: mating projection tip namespace: cellular_component def: "The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth." [GOC:mcc] synonym: "conjugation tube tip" NARROW [] synonym: "shmoo tip" NARROW [] xref: GO:0043332 is_a: CCO:C0001007 ! site of polarized growth is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0000488 ! mating projection [Term] id: CCO:C0001771 name: pre-T cell receptor complex namespace: cellular_component def: "A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins." [ISBN:0781735149 "Fundamental Immunology", PMID:12220932] synonym: "pre-T lymphocyte receptor complex" EXACT [] synonym: "pre-T-cell receptor complex" EXACT [] synonym: "pre-T-lymphocyte receptor complex" EXACT [] synonym: "pre-TCR complex" EXACT [] xref: GO:0043384 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001772 name: phage terminase complex namespace: cellular_component def: "A complex of a large and small subunit which catalyze the packaging of DNA into phage heads. Note that not all phage terminases have this structure, some exist as single polypeptides." [GOC:mlg] xref: GO:0043493 is_a: CCO:C0001599 ! host cell cytoplasm part is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0001773 name: Rik1-E3 ubiquitin ligase complex namespace: cellular_component def: "A protein complex that consists of (minimally) cullin, RING finger, methyltransferase, Rik1 WD repeat protein, Raf1 and Raf2. Required to regulate heterchromatin formation by RNAi and for histone H3K9 methylation." [GOC:jl, PMID:16024659, PMID:16040243] synonym: "Rik1 E3 ubiquitin ligase complex" EXACT [] xref: GO:0043494 is_a: CCO:C0001252 ! Cul4B-RING ubiquitin ligase complex [Term] id: CCO:C0001774 name: centromere-specific nucleosome namespace: cellular_component def: "A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3)." [GOC:go_curators, PMID:15175412, PMID:16183641] synonym: "centromere specific nucleosome" EXACT [] synonym: "centromeric nucleosome" EXACT [] xref: GO:0043505 is_a: CCO:C0000113 ! nucleosome relationship: part_of CCO:C0000158 ! inner kinetochore of condensed chromosome [Term] id: CCO:C0001775 name: activin A complex namespace: cellular_component def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A)." [GOC:go_curators] comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'. xref: GO:0043509 xref: GO:0048181 is_a: CCO:C0001981 ! activin complex relationship: location_of CCO:B0001498 ! INHBA_HUMAN [Term] id: CCO:C0001776 name: activin B complex namespace: cellular_component def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B)." [GOC:go_curators] comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'. xref: GO:0043510 xref: GO:0048182 is_a: CCO:C0001981 ! activin complex [Term] id: CCO:C0001777 name: inhibin complex namespace: cellular_component def: "Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B." [GOC:jl] comment: Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'. subset: goslim_pir xref: GO:0043511 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0001778 name: inhibin A complex namespace: cellular_component def: "Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit." [GOC:jl] comment: Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'. xref: GO:0043512 is_a: CCO:C0001777 ! inhibin complex relationship: location_of CCO:B0001485 ! INHA_HUMAN relationship: location_of CCO:B0001498 ! INHBA_HUMAN [Term] id: CCO:C0001779 name: inhibin B complex namespace: cellular_component def: "Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit." [GOC:jl] comment: Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'. xref: GO:0043513 is_a: CCO:C0001777 ! inhibin complex [Term] id: CCO:C0001780 name: interleukin-12 complex namespace: cellular_component def: "Secreted heterodimeric cytokine complex composed of an interleukin-12 alpha and an interleukin-12 beta subunit." [GOC:ebc] synonym: "IL-12 complex" EXACT [] xref: GO:0043514 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0043824 ! IL12B_HUMAN relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0001781 name: tRNA methyltransferase complex namespace: cellular_component def: "A multimeric protein complex involved in the methylation of specific nucleotides in tRNA." [GOC:jl] subset: goslim_pir xref: GO:0043527 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001782 name: tRNA (m2G10) methyltransferase complex namespace: cellular_component def: "A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p." [PMID:15899842] xref: GO:0043528 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001781 ! tRNA methyltransferase complex [Term] id: CCO:C0001783 name: GET complex namespace: cellular_component def: "A multisubunit complex involved in ER/Golgi trafficking (Golgi to ER Traffic). In yeast, includes Get1p, Get2p and Get3p proteins." [PMID:16269340] synonym: "Golgi to ER Traffic complex" EXACT [] xref: GO:0043529 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001851 ! endoplasmic reticulum part [Term] id: CCO:C0001784 name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex namespace: cellular_component def: "A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis." [GOC:jl, InterPro:SO] xref: GO:0043540 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0034772 ! F261_HUMAN-Phosphoserine33 [Term] id: CCO:C0001785 name: UDP-N-acetylglucosamine transferase complex namespace: cellular_component def: "A heterooligomeric complex that in yeast is composed of a catalytic subunit, Alg13p, and an anchoring subunit, Alg14p. Catalyzes the second step of dolichyl-linked oligosaccharide synthesis of GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc." [PMID:15615718, PMID:16100110, PMID:16100113] comment: See also the molecular function term 'N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ; GO:0004577'. xref: GO:0043541 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001851 ! endoplasmic reticulum part relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0001786 name: Ku70:Ku80 complex namespace: cellular_component def: "Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK." [PMID:12518983, UniProtKB:P12956] synonym: "Ku70:Ku80 heterodimer" EXACT [] xref: GO:0043564 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001787 name: bacterial nucleoid namespace: cellular_component def: "The region of a bacterial cell to which the DNA is confined." [GOC:jl] subset: gosubset_prok xref: GO:0043590 is_a: CCO:C0000563 ! nucleoid [Term] id: CCO:C0001788 name: endospore external encapsulating structure namespace: cellular_component def: "The structures that lie outside the inner membrane and surround the entire endospore." [GOC:go_curators] subset: goslim_pir xref: GO:0043591 is_a: CCO:C0000999 ! external encapsulating structure [Term] id: CCO:C0001789 name: exosporium namespace: cellular_component def: "The outer-most layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid." [GOC:mlg] subset: gosubset_prok synonym: "epispore" RELATED [] synonym: "exospore" RELATED [] xref: GO:0043592 is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0001788 ! endospore external encapsulating structure [Term] id: CCO:C0001790 name: endospore coat namespace: cellular_component def: "The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination." [GOC:mlg] subset: gosubset_prok xref: GO:0043593 is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0001788 ! endospore external encapsulating structure [Term] id: CCO:C0001791 name: outer endospore membrane namespace: cellular_component def: "The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat." [GOC:mlg] subset: gosubset_prok xref: GO:0043594 is_a: CCO:C0000898 ! outer membrane is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0001788 ! endospore external encapsulating structure [Term] id: CCO:C0001792 name: endospore cortex namespace: cellular_component def: "A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan." [GOC:mlg] subset: gosubset_prok xref: GO:0043595 is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0001788 ! endospore external encapsulating structure [Term] id: CCO:C0001793 name: nuclear replication fork namespace: cellular_component def: "The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes." [GOC:jl, GOC:mtg_sensu] synonym: "replication fork (sensu Eukaryota)" EXACT [] xref: GO:0043596 is_a: CCO:C0000265 ! replication fork is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0005218 ! ZMIZ2_HUMAN [Term] id: CCO:C0001794 name: cytoplasmic replication fork namespace: cellular_component def: "The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes." [GOC:jl, GOC:mtg_sensu] synonym: "replication fork (sensu Bacteria and Archaea)" EXACT [] xref: GO:0043597 is_a: CCO:C0000265 ! replication fork is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0000041 ! cytoplasmic chromosome [Term] id: CCO:C0001795 name: cytoplasmic DNA replication factor C complex namespace: cellular_component def: "A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase." [GOC:mtg_sensu, PMID:14646196, PMID:16172520] synonym: "DNA replication factor C complex (sensu Bacteria and Archaea)" EXACT [] xref: GO:0043598 is_a: CCO:C0000268 ! DNA replication factor C complex is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001797 ! cytoplasmic replisome [Term] id: CCO:C0001796 name: nuclear DNA replication factor C complex namespace: cellular_component def: "A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species." [GOC:mtg_sensu, PMID:14614842] synonym: "DNA replication factor C complex (sensu Eukaryota)" EXACT [] xref: GO:0043599 is_a: CCO:C0000268 ! DNA replication factor C complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0001798 ! nuclear replisome [Term] id: CCO:C0001797 name: cytoplasmic replisome namespace: cellular_component def: "A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins." [GOC:jl, GOC:mtg_sensu] synonym: "replisome (sensu Bacteria and Archaea)" EXACT [] xref: GO:0043600 is_a: CCO:C0001072 ! replisome is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001794 ! cytoplasmic replication fork [Term] id: CCO:C0001798 name: nuclear replisome namespace: cellular_component def: "A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins." [GOC:jl, GOC:mtg_sensu] synonym: "replisome (sensu Eukaryota)" EXACT [] xref: GO:0043601 is_a: CCO:C0001072 ! replisome is_a: CCO:C0001873 ! nuclear chromosome part relationship: part_of CCO:C0001793 ! nuclear replication fork [Term] id: CCO:C0001799 name: multi-eIF complex namespace: cellular_component def: "A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preintiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5." [GOC:krc] synonym: "multifactor translation initiation factor (eIF) complex" EXACT [] xref: GO:0043614 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001800 name: delta DNA polymerase complex namespace: cellular_component def: "A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair." [GOC:jl, ISBN:0198547684, PMID:11205330, PMID:12403614] synonym: "delta-DNA polymerase complex" EXACT [] xref: GO:0005659 xref: GO:0043625 is_a: CCO:C0001651 ! DNA polymerase complex is_a: CCO:C0001873 ! nuclear chromosome part relationship: location_of CCO:B0005884 ! DPOD3_HUMAN relationship: part_of CCO:C0001798 ! nuclear replisome [Term] id: CCO:C0001801 name: PCNA complex namespace: cellular_component def: "A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation." [GOC:jl, PMID:12829735] subset: gosubset_prok synonym: "proliferating cell nuclear antigen complex" EXACT [] synonym: "sliding clamp" BROAD [] xref: GO:0043626 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001513 ! PCNA_HUMAN [Term] id: CCO:C0001802 name: extracellular space of host namespace: cellular_component def: "The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream." [GOC:cc] subset: gosubset_prok synonym: "host extracellular space" EXACT [] xref: GO:0043655 is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000849 ! host [Term] id: CCO:C0001803 name: intracellular region of host namespace: cellular_component def: "That space within the plasma membrane of a host cell." [GOC:cc] subset: gosubset_prok synonym: "host intracellular" EXACT [] xref: GO:0043656 is_a: CCO:C0001588 ! host cell part [Term] id: CCO:C0001804 name: host cell namespace: cellular_component def: "A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope." [GOC:jl] subset: gosubset_prok xref: GO:0043657 is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000849 ! host [Term] id: CCO:C0001805 name: host symbiosome namespace: cellular_component def: "A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell." [GOC:cc] subset: gosubset_prok xref: GO:0043658 is_a: CCO:C0001599 ! host cell cytoplasm part is_a: CCO:C0002126 ! host intracellular membrane-bounded organelle [Term] id: CCO:C0001806 name: symbiosome namespace: cellular_component def: "A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane)." [GOC:cc] subset: gosubset_prok xref: GO:0043659 is_a: CCO:C0000983 ! endocytic vesicle [Term] id: CCO:C0001807 name: bacteroid-containing symbiosome namespace: cellular_component def: "A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants." [GOC:cc] subset: gosubset_prok xref: GO:0043660 is_a: CCO:C0001806 ! symbiosome [Term] id: CCO:C0001808 name: peribacteroid membrane namespace: cellular_component def: "A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells)." [GOC:cc] subset: gosubset_prok xref: GO:0043661 is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001807 ! bacteroid-containing symbiosome [Term] id: CCO:C0001809 name: peribacteroid fluid namespace: cellular_component def: "The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome." [GOC:cc] subset: gosubset_prok xref: GO:0043662 is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001807 ! bacteroid-containing symbiosome [Term] id: CCO:C0001810 name: host bacteroid-containing symbiosome namespace: cellular_component def: "A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell." [GOC:cc] subset: gosubset_prok xref: GO:0043663 is_a: CCO:C0001805 ! host symbiosome [Term] id: CCO:C0001811 name: host peribacteroid membrane namespace: cellular_component def: "A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells)." [GOC:cc] subset: gosubset_prok xref: GO:0043664 is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001810 ! host bacteroid-containing symbiosome [Term] id: CCO:C0001812 name: host peribacteroid fluid namespace: cellular_component def: "The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell." [GOC:cc] subset: gosubset_prok xref: GO:0043665 is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001810 ! host bacteroid-containing symbiosome [Term] id: CCO:C0001813 name: pollen wall namespace: cellular_component def: "The complex wall surrounding a pollen grain." [GOC:fz] comment: Note that this term is a child of 'extracellular matrix part ; GO:0044420' rather than the more specific 'extracellular matrix (sensu Magnoliophyta) ; GO:0048196', because unlike the usual plant cell wall, the pollen wall does not contain a middle lamella, as specified in the definition of 'extracellular matrix (sensu Magnoliophyta) ; GO:0048196'. synonym: "micrsopore wall" EXACT [] xref: GO:0043667 is_a: CCO:C0001839 ! extracellular matrix part [Term] id: CCO:C0001814 name: exine namespace: cellular_component def: "The outer layer of the pollen grain wall which is composed primarily of sporopollenin." [http://www.mobot.org/MOBOT/research/APweb/] comment: Note that the exine is highly resistant to strong acids and bases. xref: GO:0043668 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001813 ! pollen wall [Term] id: CCO:C0001815 name: ectexine namespace: cellular_component def: "The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections." [http://www.mobot.org/MOBOT/research/APweb/] comment: Note that ectexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'endexine ; GO:0043671'. xref: GO:0043669 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001814 ! exine [Term] id: CCO:C0001816 name: foot layer namespace: cellular_component def: "The inner layer of the ectexine." [http://www.mobot.org/MOBOT/research/APweb/] synonym: "nexine 1" EXACT [] xref: GO:0043670 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001815 ! ectexine [Term] id: CCO:C0001817 name: endexine namespace: cellular_component def: "The inner part of the exine, which stains." [http://www.mobot.org/MOBOT/research/APweb/] comment: Note that endexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'ectexine ; GO:0043669'. xref: GO:0043671 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001814 ! exine [Term] id: CCO:C0001818 name: nexine namespace: cellular_component def: "The inner, non-sculptured part of the exine which lies below the sexine." [http://www.mobot.org/MOBOT/research/APweb/] comment: Note that nexine is distinguished on purely morphological criteria; compare with 'endexine ; GO:0043671'. See also 'sexine ; GO:0043673'. xref: GO:0043672 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001814 ! exine [Term] id: CCO:C0001819 name: sexine namespace: cellular_component def: "The outer, sculptured layer of the exine, which lies above the nexine." [http://www.mobot.org/MOBOT/research/APweb/] comment: Note that the sexine sometimes consists of 5 layers, but of those, 3 layers are the most common (sexine 1 = columellae; sexine 2 = tectum; sexine 3 = sculpture elements). Sexine is distinguished on purely morphological criteria; compare with 'ectexine ; GO:0043669'. See also 'nexine ; GO:0043672'. xref: GO:0043673 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001814 ! exine [Term] id: CCO:C0001820 name: columella namespace: cellular_component def: "A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella)." [http://www.mobot.org/MOBOT/research/APweb/] synonym: "sexine 1" EXACT [] xref: GO:0043674 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001819 ! sexine [Term] id: CCO:C0001821 name: sculpture element namespace: cellular_component def: "The third layer of the sexine." [http://www.mobot.org/MOBOT/research/APweb/] xref: GO:0043675 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001819 ! sexine [Term] id: CCO:C0001822 name: tectum namespace: cellular_component def: "The layer of sexine which forms a roof over the columella, granules or other infratectal elements." [http://www.mobot.org/MOBOT/research/APweb/] synonym: "sexine 2" EXACT [] xref: GO:0043676 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001819 ! sexine [Term] id: CCO:C0001823 name: germination pore namespace: cellular_component def: "A small pore in the outer wall of a mycelial spore through which the germ tube exits upon germination. It can be apical or eccentric in its location." [http://en.wikipedia.org/] synonym: "germ pore" EXACT [] xref: GO:0043677 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001813 ! pollen wall [Term] id: CCO:C0001824 name: intine namespace: cellular_component def: "The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm." [http://www.mobot.org/MOBOT/research/APweb/] comment: Note that the intine is not acetolysis resistant and is therefore absent in conventionally prepared palynological material. xref: GO:0043678 is_a: CCO:C0001839 ! extracellular matrix part relationship: part_of CCO:C0001813 ! pollen wall [Term] id: CCO:C0001825 name: nerve terminal namespace: cellular_component def: "A cell projection in which the distal end of the axon of a nerve fiber terminates. Sensory nerve endings are classified as either free or encapsulated. The free nerve ending are the most common type of nerve ending, and are most frequently found in the skin." [GOC:ef, GOC:mah] synonym: "nerve ending" EXACT [] xref: GO:0043679 is_a: CCO:C0001562 ! axon part [Term] id: CCO:C0001826 name: filiform apparatus namespace: cellular_component def: "A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells." [ISBN:0471245208] xref: GO:0043680 is_a: CCO:C0001845 ! cell wall part [Term] id: CCO:C0001827 name: type IV protein secretion system complex namespace: cellular_component def: "A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of nucleoprotein DNA conjugation intermediates or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s)." [GOC:ml] subset: gosubset_prok synonym: "T4SS complex" EXACT [] xref: GO:0043684 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0001828 name: iridosome namespace: cellular_component def: "A tissue-specific, membrane bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance." [GOC:mh] synonym: "reflecting platelet" EXACT [] xref: GO:0043698 is_a: CCO:C0002006 ! pigment granule [Term] id: CCO:C0001829 name: leucosome namespace: cellular_component def: "A tissue-specific, membrane bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast." [GOC:mh] synonym: "refractosome" EXACT [] xref: GO:0043699 is_a: CCO:C0002006 ! pigment granule [Term] id: CCO:C0001830 name: pterinosome namespace: cellular_component def: "A tissue-specific, membrane bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance." [GOC:mh] xref: GO:0043700 is_a: CCO:C0002006 ! pigment granule [Term] id: CCO:C0001831 name: cyanosome namespace: cellular_component def: "A tissue-specific, membrane bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance." [GOC:mh] xref: GO:0043701 is_a: CCO:C0002006 ! pigment granule [Term] id: CCO:C0001832 name: carotenoid vesicle namespace: cellular_component def: "A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vescicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance." [GOC:mh] xref: GO:0043702 is_a: CCO:C0001235 ! cytoplasmic vesicle [Term] id: CCO:C0001835 name: DNA polymerase III, DnaX complex namespace: cellular_component def: "A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands." [PMID:12940977] subset: gosubset_prok synonym: "clamp loader complex" BROAD [] synonym: "DNA polymerase III, clamp loader complex" EXACT [] synonym: "DNA polymerase III, DnaX subcomplex" EXACT [] xref: GO:0043846 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000604 ! DNA polymerase III complex [Term] id: CCO:C0001836 name: DNA polymerase III, DnaX complex, chi/psi subcomplex namespace: cellular_component def: "A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III DnaX complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB)." [IMG:01719, PMID:12940977] subset: gosubset_prok synonym: "DNA polymerase III, clamp loader chi/psi subcomplex" EXACT [] xref: GO:0043847 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0001835 ! DNA polymerase III, DnaX complex [Term] id: CCO:C0001837 name: RecFOR complex namespace: cellular_component def: "A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair." [IMG:01764, PMID:12769856] subset: gosubset_prok xref: GO:0043850 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001846 ! chromosomal part [Term] id: CCO:C0001838 name: methanol-CoM methyltransferase complex namespace: cellular_component def: "A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol." [IMG:01437, MetaCyc:CPLX-421, PMID:9363780] subset: gosubset_prok synonym: "methanol-coenzyme M methyltransferase complex" EXACT [] synonym: "methanol: coenzyme M methyltransferase complex" EXACT [] synonym: "methanol: CoM methyltransferase complex" EXACT [] synonym: "methanol:coenzyme M methyltransferase complex" EXACT [] synonym: "methanol:CoM methyltransferase complex" EXACT [] xref: GO:0043853 xref: MetaCyc:CPLX-421 is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001839 name: extracellular matrix part namespace: cellular_component def: "Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants)." [GOC:jl] subset: gosubset_prok xref: GO:0044420 is_a: CCO:C0000200 ! cellular_component relationship: location_of CCO:B0054617 ! CILP1_HUMAN relationship: part_of CCO:C0001109 ! extracellular matrix [Term] id: CCO:C0001840 name: extracellular region part namespace: cellular_component def: "Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite." [GOC:jl] subset: gosubset_prok xref: GO:0044421 is_a: CCO:C0000200 ! cellular_component relationship: part_of CCO:C0000201 ! extracellular region [Term] id: CCO:C0001841 name: organelle part namespace: cellular_component def: "Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane." [GOC:jl] subset: gosubset_prok xref: GO:0044422 is_a: CCO:C0000200 ! cellular_component relationship: part_of CCO:C0001742 ! organelle [Term] id: CCO:C0001842 name: virion part namespace: cellular_component def: "Any constituent part of a virion, a complete fully infectious extracellular virus particle." [GOC:jl] xref: GO:0044423 is_a: CCO:C0000200 ! cellular_component relationship: part_of CCO:C0000852 ! virion [Term] id: CCO:C0001843 name: intracellular part namespace: cellular_component def: "Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [GOC:jl] subset: gosubset_prok xref: GO:0044424 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0065439 ! ADRB2_HUMAN-Phosphoserine261 relationship: part_of CCO:C0000242 ! intracellular [Term] id: CCO:C0001844 name: membrane part namespace: cellular_component def: "Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:jl] subset: gosubset_prok xref: GO:0044425 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0000766 ! membrane [Term] id: CCO:C0001845 name: cell wall part namespace: cellular_component def: "Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis." [GOC:jl] subset: gosubset_prok xref: GO:0044426 is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000239 ! cell wall [Term] id: CCO:C0001846 name: chromosomal part namespace: cellular_component def: "Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [GOC:jl] subset: gosubset_prok synonym: "chromosomal component" EXACT [] synonym: "chromosome component" EXACT [] synonym: "chromosome part" EXACT [] xref: GO:0044427 is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000296 ! chromosome [Term] id: CCO:C0001847 name: nuclear part namespace: cellular_component def: "Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated." [GOC:jl] synonym: "nucleus component" EXACT [] xref: GO:0044428 is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000252 ! nucleus [Term] id: CCO:C0001848 name: mitochondrial part namespace: cellular_component def: "Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." [GOC:jl] synonym: "mitochondrion component" EXACT [] xref: GO:0044429 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000325 ! mitochondrion [Term] id: CCO:C0001849 name: cytoskeletal part namespace: cellular_component def: "Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice." [GOC:jl] synonym: "cytoskeleton component" EXACT [] xref: GO:0044430 is_a: CCO:C0001865 ! intracellular organelle part relationship: location_of CCO:B0059410 ! IF2B2_HUMAN relationship: part_of CCO:C0000421 ! cytoskeleton [Term] id: CCO:C0001850 name: Golgi apparatus part namespace: cellular_component def: "Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack." [GOC:jl] synonym: "Golgi component" EXACT [] xref: GO:0044431 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000375 ! Golgi apparatus [Term] id: CCO:C0001851 name: endoplasmic reticulum part namespace: cellular_component def: "Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae." [GOC:jl] synonym: "ER component" EXACT [] xref: GO:0044432 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000364 ! endoplasmic reticulum [Term] id: CCO:C0001852 name: cytoplasmic vesicle part namespace: cellular_component def: "Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell." [GOC:jl] subset: gosubset_prok xref: GO:0044433 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0001235 ! cytoplasmic vesicle [Term] id: CCO:C0001853 name: chloroplast part namespace: cellular_component def: "Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma." [GOC:jl] xref: GO:0044434 is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0000636 ! chloroplast [Term] id: CCO:C0001854 name: plastid part namespace: cellular_component def: "Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid." [GOC:jl] subset: gosubset_prok xref: GO:0044435 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000664 ! plastid [Term] id: CCO:C0001855 name: thylakoid part namespace: cellular_component def: "Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms." [GOC:jl] subset: gosubset_prok xref: GO:0044436 is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000689 ! thylakoid [Term] id: CCO:C0001856 name: vacuolar part namespace: cellular_component def: "Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material." [GOC:jl] subset: gosubset_prok synonym: "vacuole component" EXACT [] xref: GO:0044437 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000355 ! vacuole [Term] id: CCO:C0001857 name: microbody part namespace: cellular_component def: "Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)." [GOC:jl] xref: GO:0044438 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0001652 ! microbody [Term] id: CCO:C0001858 name: peroxisomal part namespace: cellular_component def: "Any constituent part of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2)." [GOC:jl] synonym: "peroxisome component" EXACT [] xref: GO:0044439 is_a: CCO:C0001857 ! microbody part relationship: part_of CCO:C0000359 ! peroxisome [Term] id: CCO:C0001859 name: endosomal part namespace: cellular_component def: "Any constituent part of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation." [GOC:jl] synonym: "endosome component" EXACT [] xref: GO:0044440 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000351 ! endosome [Term] id: CCO:C0001860 name: cilium part namespace: cellular_component def: "Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:jl] xref: GO:0044441 is_a: CCO:C0001865 ! intracellular organelle part is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0000481 ! cilium [Term] id: CCO:C0001861 name: microtubule-based flagellum part namespace: cellular_component def: "Any constituent part of a microtubule-based flagellum, a long, whiplike protrusion from the surface of a eukaryotic cell, whose undulations drive the cell through a liquid medium; similar in structure to a cilium. The flagellum is based on a 9+2 arrangement of microtubules." [GOC:jl, GOC:mtg_sensu] synonym: "flagellar part (sensu Eukaryota)" EXACT [] synonym: "flagellum part (sensu Eukaryota)" EXACT [] xref: GO:0044442 is_a: CCO:C0001865 ! intracellular organelle part is_a: CCO:C0001878 ! flagellum part relationship: part_of CCO:C0000629 ! microtubule-based flagellum [Term] id: CCO:C0001862 name: fimbrial part namespace: cellular_component def: "Any constituent part of a fimbrium, a proteinaceous hair-like appendage on the surface of bacteria; range from 2-8 nm in diameter." [GOC:jl] subset: gosubset_prok synonym: "fimbrium component" EXACT [] xref: GO:0044443 is_a: CCO:C0001865 ! intracellular organelle part relationship: part_of CCO:C0000562 ! fimbrium [Term] id: CCO:C0001863 name: cytoplasmic part namespace: cellular_component def: "Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:jl] subset: gosubset_prok synonym: "cytoplasm component" EXACT [] xref: GO:0044444 is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0041164 ! NEMO_HUMAN-Phosphoserine43 relationship: part_of CCO:C0000324 ! cytoplasm [Term] id: CCO:C0001864 name: cytosolic part namespace: cellular_component def: "Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:jl] subset: gosubset_prok synonym: "cytosol component" EXACT [] xref: GO:0044445 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0065581 ! AKTS1_HUMAN-Phosphoserine116 relationship: part_of CCO:C0000397 ! cytosol [Term] id: CCO:C0001865 name: intracellular organelle part namespace: cellular_component def: "A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane." [GOC:jl] subset: gosubset_prok xref: GO:0044446 is_a: CCO:C0001841 ! organelle part is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0001745 ! intracellular organelle [Term] id: CCO:C0001866 name: axoneme part namespace: cellular_component def: "Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia and flagella in eukaryotic cells and is responsible for their movements." [GOC:jl] xref: GO:0044447 is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0000482 ! axoneme [Term] id: CCO:C0001867 name: cell cortex part namespace: cellular_component def: "Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:jl] xref: GO:0044448 is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0000489 ! cell cortex [Term] id: CCO:C0001868 name: contractile fiber part namespace: cellular_component def: "Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:jl] synonym: "contractile fibre component" EXACT [] synonym: "muscle fiber component" BROAD [] synonym: "muscle fibre component" BROAD [] xref: GO:0044449 is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001766 ! contractile fiber [Term] id: CCO:C0001869 name: microtubule organizing center part namespace: cellular_component def: "Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow." [GOC:jl] synonym: "microtubule organizing centre component" EXACT [] synonym: "MTOC component" EXACT [] xref: GO:0044450 is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0000385 ! microtubule organizing center [Term] id: CCO:C0001870 name: nucleoplasm part namespace: cellular_component def: "Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus." [GOC:jl] xref: GO:0044451 is_a: CCO:C0001847 ! nuclear part relationship: part_of CCO:C0000262 ! nucleoplasm [Term] id: CCO:C0001871 name: nucleolar part namespace: cellular_component def: "Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis." [GOC:jl] synonym: "nucleolus component" EXACT [] xref: GO:0044452 is_a: CCO:C0001847 ! nuclear part relationship: part_of CCO:C0000320 ! nucleolus [Term] id: CCO:C0001872 name: nuclear membrane part namespace: cellular_component def: "Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells." [GOC:jl] xref: GO:0044453 is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001847 ! nuclear part relationship: part_of CCO:C0001358 ! nuclear membrane [Term] id: CCO:C0001873 name: nuclear chromosome part namespace: cellular_component def: "Any constituent part of a nuclear chromosome, a chromosome found in the nucleus of a eukaryotic cell." [GOC:jl] xref: GO:0044454 is_a: CCO:C0001846 ! chromosomal part is_a: CCO:C0001847 ! nuclear part relationship: part_of CCO:C0000040 ! nuclear chromosome [Term] id: CCO:C0001874 name: mitochondrial membrane part namespace: cellular_component def: "Any constituent part of the mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." [GOC:jl] xref: GO:0044455 is_a: CCO:C0001844 ! membrane part is_a: CCO:C0001848 ! mitochondrial part relationship: part_of CCO:C0001359 ! mitochondrial membrane [Term] id: CCO:C0001875 name: synapse part namespace: cellular_component def: "Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:jl] xref: GO:0044456 is_a: CCO:C0000200 ! cellular_component relationship: part_of CCO:C0001900 ! synapse [Term] id: CCO:C0001876 name: cell septum part namespace: cellular_component def: "Any constituent part of a cell septum, a structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells." [GOC:jl] xref: GO:0044457 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0001008 ! cell septum [Term] id: CCO:C0001877 name: plasma membrane part namespace: cellular_component def: "Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [GOC:jl] subset: gosubset_prok xref: GO:0044459 is_a: CCO:C0001844 ! membrane part relationship: part_of CCO:C0000444 ! plasma membrane [Term] id: CCO:C0001878 name: flagellum part namespace: cellular_component def: "Any constituent part of a flagellum, a long whiplike or feathery structure borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium." [GOC:jl] subset: gosubset_prok synonym: "flagellum component" EXACT [] xref: GO:0044460 is_a: CCO:C0001881 ! cell projection part relationship: part_of CCO:C0000896 ! flagellum [Term] id: CCO:C0001879 name: flagellin-based flagellum part namespace: cellular_component def: "Any constituent part of flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by the transmembrane proton potential." [GOC:jl, GOC:mtg_sensu] subset: gosubset_prok synonym: "flagellar part (sensu Bacteria)" EXACT [] synonym: "flagellum part (sensu Bacteria)" EXACT [] xref: GO:0044461 is_a: CCO:C0001878 ! flagellum part relationship: part_of CCO:C0000561 ! flagellin-based flagellum [Term] id: CCO:C0001880 name: external encapsulating structure part namespace: cellular_component def: "Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell." [GOC:jl] subset: gosubset_prok xref: GO:0044462 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0000999 ! external encapsulating structure [Term] id: CCO:C0001881 name: cell projection part namespace: cellular_component def: "Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl] subset: gosubset_prok xref: GO:0044463 is_a: CCO:C0001882 ! cell part relationship: part_of CCO:C0001706 ! cell projection [Term] id: CCO:C0001882 name: cell part namespace: cellular_component def: "Any constituent part of a cell, the basic structural and functional unit of all organisms." [GOC:jl] subset: goslim_pir subset: gosubset_prok xref: GO:0044464 is_a: CCO:C0000200 ! cellular_component relationship: part_of CCO:C0000243 ! cell [Term] id: CCO:C0001883 name: chitosome namespace: cellular_component def: "An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:8970154] xref: GO:0045009 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0001884 name: mitochondrial degradosome namespace: cellular_component def: "The mitochondrial degradosome (mtEXO) is a three-protein complex which has a 3' to 5' exoribonuclease activity and participates in intron-independent turnover and processing of mitochondrial transcripts." [PMID:10397341, PMID:9829834] xref: GO:0045025 is_a: CCO:C0001848 ! mitochondrial part [Term] id: CCO:C0001885 name: interleukin-18 receptor complex namespace: cellular_component def: "Complex that binds interleukin-18; comprises an alpha and a beta subunit." [GOC:mah, PMID:12759435] xref: GO:0045092 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005273 ! TOLIP_HUMAN relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001886 name: keratin filament namespace: cellular_component def: "A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins." [ISBN:0716731363] synonym: "acidic keratin" RELATED [] synonym: "basic/neutral keratin" RELATED [] xref: GO:0045095 is_a: CCO:C0000440 ! intermediate filament relationship: location_of CCO:B0005293 ! KR412_HUMAN relationship: location_of CCO:B0005811 ! K2C5_HUMAN relationship: location_of CCO:B0005817 ! K1C14_HUMAN relationship: location_of CCO:B0012464 ! K1C18_HUMAN-Phosphoserine15 [Term] id: CCO:C0001887 name: type III intermediate filament namespace: cellular_component def: "A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments." [ISBN:0716731363] synonym: "desmin" NARROW [] synonym: "glial fibrillary acidic protein" NARROW [] synonym: "peripherin" NARROW [] synonym: "type III intermediate filament associated protein" NARROW [] synonym: "vimentin" NARROW [] xref: GO:0045098 is_a: CCO:C0000440 ! intermediate filament [Term] id: CCO:C0001888 name: intermediate filament cytoskeleton namespace: cellular_component def: "Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell." [ISBN:0716731363] xref: GO:0045111 is_a: CCO:C0000421 ! cytoskeleton [Term] id: CCO:C0001889 name: pronucleus namespace: cellular_component def: "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0045120 is_a: CCO:C0000252 ! nucleus relationship: location_of CCO:B0011292 ! CND1_HUMAN-Phosphoserine1376 [Term] id: CCO:C0001891 name: myosin I complex namespace: cellular_component def: "A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html, PMID:9438839] xref: GO:0045160 is_a: CCO:C0000790 ! unconventional myosin complex [Term] id: CCO:C0001892 name: fusome namespace: cellular_component def: "A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle." [GOC:bf, PMID:12655376] xref: GO:0045169 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001893 name: spectrosome namespace: cellular_component def: "A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome." [GOC:bf] xref: GO:0045170 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0002130 ! intracellular non-membrane-bounded organelle [Term] id: CCO:C0001894 name: intercellular bridge namespace: cellular_component def: "A direct link between the cytoplasms of sister cells that allows cells to communicate with one another. Germline intercellular bridges facilitate the passage of cytoplasmic components between cells during development. Intercellular bridges have also been found connecting somatic cells." [PMID:9635420] xref: GO:0045171 is_a: CCO:C0001840 ! extracellular region part relationship: location_of CCO:B0056054 ! RAB35_HUMAN [Term] id: CCO:C0001895 name: germline ring canal namespace: cellular_component def: "Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells." [GOC:mtg_sensu, PMID:9635420, PMID:9655801] synonym: "ring canal (sensu Insecta)" EXACT [] xref: GO:0045172 is_a: CCO:C0001894 ! intercellular bridge [Term] id: CCO:C0001896 name: apical part of cell namespace: cellular_component def: "The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue." [GOC:mah, ISBN:0815316194] subset: goslim_pir xref: GO:0045177 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0002113 ! PAR6B_HUMAN relationship: location_of CCO:B0002265 ! USH1C_HUMAN relationship: location_of CCO:B0011378 ! CTNB1_HUMAN-Phosphotyrosine86 relationship: location_of CCO:B0012631 ! KPCI_HUMAN-Phosphotyrosine325 relationship: location_of CCO:B0015673 ! CHL1_HUMAN relationship: location_of CCO:B0025070 ! PDZD3_HUMAN relationship: location_of CCO:B0026213 ! ITA8_HUMAN relationship: location_of CCO:B0034771 ! EZRI_HUMAN-Phosphotyrosine354 relationship: location_of CCO:B0035202 ! MOES_HUMAN-Phosphothreonine558 relationship: location_of CCO:B0035985 ! ACVR1_HUMAN-Phosphoserine501 relationship: location_of CCO:B0054549 ! FZD6_HUMAN relationship: location_of CCO:B0055107 ! VCAM1_HUMAN relationship: location_of CCO:B0055215 ! NOS3_HUMAN relationship: location_of CCO:B0058851 ! FZD3_HUMAN relationship: location_of CCO:B0059250 ! EDAR_HUMAN [Term] id: CCO:C0001897 name: basal part of cell namespace: cellular_component def: "The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue." [GOC:bmah, ISBN:0185316194] subset: goslim_pir xref: GO:0045178 is_a: CCO:C0001882 ! cell part relationship: location_of CCO:B0064831 ! DOCK7_HUMAN-Phosphoserine1432 [Term] id: CCO:C0001898 name: apical cortex namespace: cellular_component def: "The region that lies just beneath the plasma membrane on the apical edge of a cell." [GOC:bf] xref: GO:0045179 is_a: CCO:C0001867 ! cell cortex part relationship: part_of CCO:C0001896 ! apical part of cell [Term] id: CCO:C0001899 name: basal cortex namespace: cellular_component def: "The region that lies just beneath the plasma membrane on the basal edge of a cell." [GOC:bf] xref: GO:0045180 is_a: CCO:C0001867 ! cell cortex part relationship: part_of CCO:C0001897 ! basal part of cell [Term] id: CCO:C0001900 name: synapse namespace: cellular_component def: "The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir synonym: "synaptic junction" EXACT [] xref: GO:0045202 is_a: CCO:C0000200 ! cellular_component relationship: location_of CCO:B0001344 ! APBB1_HUMAN relationship: location_of CCO:B0001998 ! Q8TEY4_HUMAN relationship: location_of CCO:B0002020 ! APBB2_HUMAN relationship: location_of CCO:B0002060 ! NEB2_HUMAN relationship: location_of CCO:B0002198 ! SEPT3_HUMAN relationship: location_of CCO:B0002248 ! LZTS1_HUMAN relationship: location_of CCO:B0002265 ! USH1C_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0005954 ! DTNA_HUMAN relationship: location_of CCO:B0006285 ! GRIK5_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0010396 ! ABI1_HUMAN-Phosphoserine225 relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: location_of CCO:B0020605 ! GRIK3_HUMAN relationship: location_of CCO:B0020611 ! GRIK2_HUMAN relationship: location_of CCO:B0020614 ! GRIK1_HUMAN relationship: location_of CCO:B0020617 ! GRIK4_HUMAN relationship: location_of CCO:B0020623 ! GRIA4_HUMAN relationship: location_of CCO:B0022899 ! GBRR2_HUMAN relationship: location_of CCO:B0022900 ! GBRG3_HUMAN relationship: location_of CCO:B0022901 ! GBRE_HUMAN relationship: location_of CCO:B0022902 ! Q8IYR7_HUMAN relationship: location_of CCO:B0022903 ! GBRT_HUMAN relationship: location_of CCO:B0022906 ! GBRG1_HUMAN relationship: location_of CCO:B0022907 ! GBRA6_HUMAN relationship: location_of CCO:B0022909 ! GBRG2_HUMAN relationship: location_of CCO:B0022911 ! GLRB_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022914 ! GBRA1_HUMAN relationship: location_of CCO:B0022915 ! GBRA5_HUMAN relationship: location_of CCO:B0022917 ! GLRA2_HUMAN relationship: location_of CCO:B0022924 ! GBRA2_HUMAN relationship: location_of CCO:B0022926 ! GBRR1_HUMAN relationship: location_of CCO:B0022931 ! GBRD_HUMAN relationship: location_of CCO:B0022933 ! GBRA3_HUMAN relationship: location_of CCO:B0022935 ! Q6PCC3_HUMAN relationship: location_of CCO:B0023320 ! DLG2_HUMAN relationship: location_of CCO:B0025035 ! Q7Z324_HUMAN relationship: location_of CCO:B0027056 ! A8MWU7_HUMAN relationship: location_of CCO:B0030754 ! VAMP3_HUMAN-Phosphoserine58 relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0032799 ! ACHB3_HUMAN relationship: location_of CCO:B0032804 ! ACHA3_HUMAN relationship: location_of CCO:B0032806 ! ACHA5_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0032809 ! ACHA2_HUMAN relationship: location_of CCO:B0034706 ! DLG4_HUMAN-Phosphotyrosine432 relationship: location_of CCO:B0034992 ! KCC2A_HUMAN-Phosphothreonine286 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035292 ! NMDE4_HUMAN-Phosphoserine1326 relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0040627 ! ITSN1_HUMAN-Phosphoserine902 relationship: location_of CCO:B0040655 ! SYT1_HUMAN-Phosphotyrosine230 relationship: location_of CCO:B0042293 ! ACHG_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 relationship: location_of CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: location_of CCO:B0048252 ! EFNB1_HUMAN-Phosphotyrosine317 relationship: location_of CCO:B0048398 ! SNAPN_HUMAN-Phosphoserine133 relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0055564 ! CABP4_HUMAN relationship: location_of CCO:B0056938 ! SHC4_HUMAN relationship: location_of CCO:B0056974 ! DNMBP_HUMAN relationship: location_of CCO:B0057307 ! HOME1_HUMAN relationship: location_of CCO:B0057446 ! NLGN1_HUMAN relationship: location_of CCO:B0057556 ! UN13C_HUMAN relationship: location_of CCO:B0057992 ! CPLX3_HUMAN relationship: location_of CCO:B0058646 ! ACH10_HUMAN relationship: location_of CCO:B0058913 ! HOME2_HUMAN relationship: location_of CCO:B0059343 ! GRIP1_HUMAN relationship: location_of CCO:B0062819 ! PRAF1_HUMAN relationship: location_of CCO:B0062858 ! SNP23_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0063442 ! TUTLA_HUMAN relationship: location_of CCO:B0064449 ! CPEB1_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0064451 ! CPLX4_HUMAN-Cysteine methyl ester157 relationship: location_of CCO:B0064569 ! CTBP2_HUMAN-Phosphoserine428 relationship: location_of CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: location_of CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: location_of CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066606 ! GRIA2_HUMAN-Phosphoserine880 relationship: location_of CCO:B0066608 ! GRIA3_HUMAN-Phosphotyrosine887 relationship: location_of CCO:B0066630 ! GRP2_HUMAN-Phosphoserine116 relationship: location_of CCO:B0066889 ! HOME3_HUMAN-Phosphoserine159 relationship: location_of CCO:B0067487 ! KS6B1_HUMAN-Phosphoserine441 relationship: location_of CCO:B0067856 ! MAGI2_HUMAN-Phosphotyrosine827 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068580 ! NEUM_HUMAN-Phosphoserine41 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0068994 ! OREX_HUMAN-Methionine amide97 relationship: location_of CCO:B0069451 ! PP1G_HUMAN-Phosphothreonine307 relationship: location_of CCO:B0069566 ! PSD3_HUMAN-Phosphoserine1011 relationship: location_of CCO:B0070479 ! SHAN2_HUMAN-Phosphoserine1113 relationship: location_of CCO:B0070486 ! SHAN3_HUMAN-Phosphoserine783 relationship: location_of CCO:B0070689 ! SNP25_HUMAN-Phosphoserine187 relationship: location_of CCO:B0071048 ! SYN1_HUMAN-Phosphotyrosine312 relationship: location_of CCO:B0071732 ! UN13A_HUMAN-Phosphoserine245 relationship: location_of CCO:B0071733 ! UN13B_HUMAN-Phosphothreonine605 [Term] id: CCO:C0001901 name: integral to cell outer membrane namespace: cellular_component def: "Located such that some or all of the gene product itself penetrates at least one phospholipid bilayer of the external outer membrane of the cell. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer." [GOC:go_curators, GOC:mtg_sensu] subset: gosubset_prok synonym: "integral to external membrane (sensu Gram-negative Bacteria)" EXACT [] synonym: "integral to external membrane (sensu Proteobacteria)" EXACT [] synonym: "integral to outer membrane (sensu Gram-negative Bacteria)" EXACT [] synonym: "integral to outer membrane (sensu Proteobacteria)" EXACT [] xref: GO:0045203 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001154 ! intrinsic to cell outer membrane [Term] id: CCO:C0001902 name: postsynaptic membrane namespace: cellular_component def: "A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0045211 is_a: CCO:C0000766 ! membrane is_a: CCO:C0001875 ! synapse part relationship: location_of CCO:B0002248 ! LZTS1_HUMAN relationship: location_of CCO:B0006285 ! GRIK5_HUMAN relationship: location_of CCO:B0006317 ! GABR1_HUMAN relationship: location_of CCO:B0011521 ! DLG1_HUMAN-Phosphoserine301 relationship: location_of CCO:B0011604 ! DYN2_HUMAN-Phosphotyrosine597 relationship: location_of CCO:B0020605 ! GRIK3_HUMAN relationship: location_of CCO:B0020611 ! GRIK2_HUMAN relationship: location_of CCO:B0020614 ! GRIK1_HUMAN relationship: location_of CCO:B0020617 ! GRIK4_HUMAN relationship: location_of CCO:B0020623 ! GRIA4_HUMAN relationship: location_of CCO:B0022899 ! GBRR2_HUMAN relationship: location_of CCO:B0022900 ! GBRG3_HUMAN relationship: location_of CCO:B0022901 ! GBRE_HUMAN relationship: location_of CCO:B0022902 ! Q8IYR7_HUMAN relationship: location_of CCO:B0022903 ! GBRT_HUMAN relationship: location_of CCO:B0022906 ! GBRG1_HUMAN relationship: location_of CCO:B0022907 ! GBRA6_HUMAN relationship: location_of CCO:B0022909 ! GBRG2_HUMAN relationship: location_of CCO:B0022911 ! GLRB_HUMAN relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0022914 ! GBRA1_HUMAN relationship: location_of CCO:B0022915 ! GBRA5_HUMAN relationship: location_of CCO:B0022917 ! GLRA2_HUMAN relationship: location_of CCO:B0022924 ! GBRA2_HUMAN relationship: location_of CCO:B0022926 ! GBRR1_HUMAN relationship: location_of CCO:B0022931 ! GBRD_HUMAN relationship: location_of CCO:B0022933 ! GBRA3_HUMAN relationship: location_of CCO:B0022935 ! Q6PCC3_HUMAN relationship: location_of CCO:B0023320 ! DLG2_HUMAN relationship: location_of CCO:B0027056 ! A8MWU7_HUMAN relationship: location_of CCO:B0027058 ! A8MX51_HUMAN relationship: location_of CCO:B0032797 ! ACHB4_HUMAN relationship: location_of CCO:B0032799 ! ACHB3_HUMAN relationship: location_of CCO:B0032804 ! ACHA3_HUMAN relationship: location_of CCO:B0032806 ! ACHA5_HUMAN relationship: location_of CCO:B0032807 ! ACHB2_HUMAN relationship: location_of CCO:B0032809 ! ACHA2_HUMAN relationship: location_of CCO:B0034706 ! DLG4_HUMAN-Phosphotyrosine432 relationship: location_of CCO:B0035269 ! NMDE1_HUMAN-Phosphoserine917 relationship: location_of CCO:B0035279 ! NMDE2_HUMAN-Phosphotyrosine962 relationship: location_of CCO:B0035292 ! NMDE4_HUMAN-Phosphoserine1326 relationship: location_of CCO:B0039240 ! GBRB3_HUMAN relationship: location_of CCO:B0039443 ! GBRB1_HUMAN-Phosphoserine448 relationship: location_of CCO:B0039444 ! GBRB2_HUMAN-Phosphotyrosine396 relationship: location_of CCO:B0042227 ! GRM7_HUMAN relationship: location_of CCO:B0042293 ! ACHG_HUMAN relationship: location_of CCO:B0042294 ! ACHE_HUMAN relationship: location_of CCO:B0043280 ! GABR2_HUMAN-Phosphoserine884 relationship: location_of CCO:B0043281 ! GBRA4_HUMAN-Phosphoserine140 relationship: location_of CCO:B0054481 ! GRID2_HUMAN relationship: location_of CCO:B0054868 ! ACHA_HUMAN relationship: location_of CCO:B0054987 ! ACHB_HUMAN relationship: location_of CCO:B0055115 ! ACM3_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055368 ! ACHA4_HUMAN relationship: location_of CCO:B0056938 ! SHC4_HUMAN relationship: location_of CCO:B0057307 ! HOME1_HUMAN relationship: location_of CCO:B0057446 ! NLGN1_HUMAN relationship: location_of CCO:B0058646 ! ACH10_HUMAN relationship: location_of CCO:B0058913 ! HOME2_HUMAN relationship: location_of CCO:B0059343 ! GRIP1_HUMAN relationship: location_of CCO:B0063033 ! GOPC_HUMAN relationship: location_of CCO:B0063269 ! LIN7B_HUMAN relationship: location_of CCO:B0063293 ! LIN7C_HUMAN relationship: location_of CCO:B0064449 ! CPEB1_HUMAN-Phosphothreonine172 relationship: location_of CCO:B0065317 ! ACHA6_HUMAN-Phosphotyrosine102 relationship: location_of CCO:B0065319 ! ACHD_HUMAN-Phosphotyrosine390 relationship: location_of CCO:B0065374 ! ACM1_HUMAN-Phosphothreonine428 relationship: location_of CCO:B0065379 ! ACM2_HUMAN-Phosphoserine234 relationship: location_of CCO:B0065383 ! ACM4_HUMAN-Phosphothreonine459 relationship: location_of CCO:B0065386 ! ACM5_HUMAN-Phosphothreonine501 relationship: location_of CCO:B0066116 ! FAIM2_HUMAN-Phosphotyrosine38 relationship: location_of CCO:B0066599 ! GRIA1_HUMAN-Phosphoserine710 relationship: location_of CCO:B0066606 ! GRIA2_HUMAN-Phosphoserine880 relationship: location_of CCO:B0066608 ! GRIA3_HUMAN-Phosphotyrosine887 relationship: location_of CCO:B0066889 ! HOME3_HUMAN-Phosphoserine159 relationship: location_of CCO:B0067291 ! KCMA1_HUMAN-Phosphotyrosine1086 relationship: location_of CCO:B0068252 ! MPDZ_HUMAN-Phosphoserine230 relationship: location_of CCO:B0068751 ! NMDZ1_HUMAN-Phosphoserine890 relationship: location_of CCO:B0069566 ! PSD3_HUMAN-Phosphoserine1011 relationship: location_of CCO:B0070479 ! SHAN2_HUMAN-Phosphoserine1113 relationship: location_of CCO:B0070486 ! SHAN3_HUMAN-Phosphoserine783 [Term] id: CCO:C0001903 name: tricarboxylic acid cycle enzyme complex namespace: cellular_component def: "Any of the heteromeric enzymes that act in the TCA cycle." [GOC:mah] subset: goslim_pir subset: gosubset_prok synonym: "TCA cycle enzyme complex" EXACT [] xref: GO:0045239 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0066301 ! FUMH_HUMAN-Phosphotyrosine491 [Term] id: CCO:C0001904 name: alpha-ketoglutarate dehydrogenase complex namespace: cellular_component def: "Complex that possesses alpha-ketoglutarate dehydrogenase activity." [GOC:mah] subset: gosubset_prok synonym: "2-oxoglutarate dehydrogenase complex" EXACT [] synonym: "dihydrolipoyl dehydrogenase complex" EXACT [] xref: GO:0045240 is_a: CCO:C0001903 ! tricarboxylic acid cycle enzyme complex [Term] id: CCO:C0001905 name: cytosolic alpha-ketoglutarate dehydrogenase complex namespace: cellular_component def: "Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "2-oxoglutarate dehydrogenase complex" BROAD [] synonym: "alpha-ketoglutarate dehydrogenase complex (sensu Bacteria)" EXACT [] xref: GO:0045241 is_a: CCO:C0001904 ! alpha-ketoglutarate dehydrogenase complex is_a: CCO:C0001909 ! cytosolic tricarboxylic acid cycle enzyme complex [Term] id: CCO:C0001906 name: isocitrate dehydrogenase complex (NAD+) namespace: cellular_component def: "Complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah] subset: gosubset_prok xref: GO:0045242 is_a: CCO:C0001903 ! tricarboxylic acid cycle enzyme complex [Term] id: CCO:C0001907 name: cytosolic isocitrate dehydrogenase complex (NAD+) namespace: cellular_component def: "Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "isocitrate dehydrogenase complex (NAD+) (sensu Bacteria)" EXACT [] xref: GO:0045243 is_a: CCO:C0001906 ! isocitrate dehydrogenase complex (NAD+) is_a: CCO:C0001909 ! cytosolic tricarboxylic acid cycle enzyme complex [Term] id: CCO:C0001908 name: succinate-CoA ligase complex (GDP-forming) namespace: cellular_component def: "A heterodimeric enzyme complex, usually composed of an alpha and beta chain and found in eukaryotes. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP." [EC:6.2.1.4, GOC:jl] synonym: "succinate-CoA ligase complex (GDP-forming) (sensu Bacteria)" NARROW [] synonym: "succinate-CoA ligase complex (GDP-forming) (sensu Eukaryota)" NARROW [] xref: GO:0008325 xref: GO:0045244 xref: GO:0045245 is_a: CCO:C0000941 ! mitochondrial tricarboxylic acid cycle enzyme complex is_a: CCO:C0001687 ! succinate-CoA ligase complex [Term] id: CCO:C0001909 name: cytosolic tricarboxylic acid cycle enzyme complex namespace: cellular_component def: "Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu] subset: gosubset_prok synonym: "TCA cycle enzyme complex (sensu Bacteria)" EXACT [] synonym: "tricarboxylic acid cycle enzyme complex (sensu Bacteria)" EXACT [] xref: GO:0045246 is_a: CCO:C0001903 ! tricarboxylic acid cycle enzyme complex [Term] id: CCO:C0001910 name: cytosolic electron transfer flavoprotein complex namespace: cellular_component def: "A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors." [GOC:mtg_sensu, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "electron transfer flavoprotein complex (sensu Bacteria)" EXACT [] xref: GO:0045247 is_a: CCO:C0001914 ! electron transfer flavoprotein complex [Term] id: CCO:C0001911 name: cytosolic oxoglutarate dehydrogenase complex namespace: cellular_component def: "A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2)." [GOC:mtg_sensu, UniProtKB:Q60597] comment: See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'. subset: gosubset_prok synonym: "oxoglutarate dehydrogenase complex (sensu Bacteria)" EXACT [] xref: GO:0045248 is_a: CCO:C0001863 ! cytoplasmic part is_a: CCO:C0001915 ! oxoglutarate dehydrogenase complex [Term] id: CCO:C0001912 name: cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex namespace: cellular_component def: "A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex." [GOC:mtg_sensu, UniProtKB:P35816] comment: See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'. subset: gosubset_prok synonym: "pyruvate dehydrogenase (lipoamide) phosphatase complex (sensu Bacteria)" EXACT [] xref: GO:0045249 is_a: CCO:C0001916 ! pyruvate dehydrogenase (lipoamide) phosphatase complex [Term] id: CCO:C0001913 name: cytosolic pyruvate dehydrogenase complex namespace: cellular_component def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order." [GOC:mtg_sensu, ISBN:0471331309 "Biochemical Pathways", ISBN:0716720094] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'. subset: gosubset_prok synonym: "pyruvate dehydrogenase complex (lipoamide) (sensu Bacteria)" EXACT [] synonym: "pyruvate dehydrogenase complex (sensu Bacteria)" EXACT [] xref: GO:0045250 is_a: CCO:C0001917 ! pyruvate dehydrogenase complex [Term] id: CCO:C0001914 name: electron transfer flavoprotein complex namespace: cellular_component def: "A protein complex containing flavin adenine dinucleotide (FAD) and acyl-CoA dehydrogenase, which form a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0045251 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001915 name: oxoglutarate dehydrogenase complex namespace: cellular_component def: "A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2)." [UniProtKB:Q60597] comment: See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'. subset: goslim_pir subset: gosubset_prok synonym: "dihydrolipoamide S-succinyltransferase complex" EXACT [] xref: GO:0045252 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0006185 ! ODO2_HUMAN [Term] id: CCO:C0001916 name: pyruvate dehydrogenase (lipoamide) phosphatase complex namespace: cellular_component def: "A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex." [UniProtKB:P35816] comment: See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'. subset: goslim_pir subset: gosubset_prok xref: GO:0045253 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001917 name: pyruvate dehydrogenase complex namespace: cellular_component def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3)." [ISBN:0716720094] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'. subset: goslim_pir subset: gosubset_prok synonym: "dihydrolipoyl dehydrogenase complex" BROAD [] synonym: "pyruvate dehydrogenase complex (lipoamide)" EXACT [] xref: GO:0009364 xref: GO:0045254 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001918 name: succinate dehydrogenase complex (ubiquinone) namespace: cellular_component def: "The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration." [GOC:kd, ISBN:0198547684] subset: gosubset_prok xref: GO:0045257 is_a: CCO:C0001941 ! succinate dehydrogenase complex [Term] id: CCO:C0001919 name: plasma membrane succinate dehydrogenase complex (ubiquinone) namespace: cellular_component def: "The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration." [GOC:kd, GOC:mtg_sensu, ISBN:0198547684] subset: gosubset_prok synonym: "succinate dehydrogenase complex (ubiquinone) (sensu Bacteria)" EXACT [] xref: GO:0045258 is_a: CCO:C0001918 ! succinate dehydrogenase complex (ubiquinone) is_a: CCO:C0001942 ! plasma membrane succinate dehydrogenase complex [Term] id: CCO:C0001920 name: proton-transporting ATP synthase complex namespace: cellular_component def: "A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient." [EC:3.6.3.14, ISBN:0198547684, ISBN:0716743663] subset: gosubset_prok synonym: "hydrogen-translocating F-type ATPase complex" EXACT [] synonym: "hydrogen-transporting ATP synthase complex" EXACT [] synonym: "proton-transporting F-type ATPase complex" RELATED [] xref: GO:0045255 xref: GO:0045259 is_a: CCO:C0000792 ! proton-transporting two-sector ATPase complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001921 name: plasma membrane proton-transporting ATP synthase complex namespace: cellular_component def: "A proton-transporting ATP synthase complex found in the plasma membrane." [GOC:mah, GOC:mtg_sensu, ISBN:0198547684] subset: gosubset_prok synonym: "hydrogen-translocating F-type ATPase complex (sensu Bacteria)" EXACT [] synonym: "hydrogen-transporting ATP synthase" EXACT [] synonym: "plasma membrane hydrogen-translocating F-type ATPase complex" EXACT [] synonym: "proton-transporting ATP synthase complex (sensu Bacteria)" EXACT [] xref: GO:0045256 xref: GO:0045260 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001920 ! proton-transporting ATP synthase complex [Term] id: CCO:C0001922 name: proton-transporting ATP synthase complex, catalytic core F(1) namespace: cellular_component def: "The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled." [GOC:mah, PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, F1 sector" EXACT [] xref: GO:0045261 is_a: CCO:C0001548 ! proton-transporting two-sector ATPase complex, catalytic domain is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0010676 ! ATPA_HUMAN-Pyrrolidone carboxylic acid44 relationship: location_of CCO:B0010689 ! ATPB_HUMAN-N6-acetyllysine522 relationship: location_of CCO:B0010692 ! ATPG_HUMAN-N6-acetyllysine90 relationship: part_of CCO:C0001920 ! proton-transporting ATP synthase complex [Term] id: CCO:C0001923 name: plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) namespace: cellular_component def: "The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled." [GOC:mah, GOC:mtg_sensu, PMID:10838056] comment: See also the cellular component term 'plasma membrane ; GO:0005886'. subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, F1 sector (sensu Bacteria)" EXACT [] synonym: "proton-transporting ATP synthase complex, catalytic core F(1) (sensu Bacteria)" EXACT [] xref: GO:0045262 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) relationship: part_of CCO:C0001921 ! plasma membrane proton-transporting ATP synthase complex [Term] id: CCO:C0001924 name: proton-transporting ATP synthase complex, coupling factor F(o) namespace: cellular_component def: "All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins." [PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, coupling factor CF(0)" NARROW [] synonym: "hydrogen-transporting ATP synthase, F0 sector" EXACT [] synonym: "proton-transporting ATP synthase complex, coupling factor F(0)" EXACT [] xref: GO:0045263 is_a: CCO:C0001547 ! proton-transporting two-sector ATPase complex, proton-transporting domain is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0065758 ! ATPK_HUMAN-N-acetylalanine2 relationship: part_of CCO:C0001920 ! proton-transporting ATP synthase complex [Term] id: CCO:C0001925 name: plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) namespace: cellular_component def: "All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins." [GOC:mah, GOC:mtg_sensu, PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, F0 sector (sensu Bacteria)" EXACT [] synonym: "proton-transporting ATP synthase complex, coupling factor F(0) (sensu Bacteria)" EXACT [] synonym: "proton-transporting ATP synthase complex, coupling factor F(o) (sensu Bacteria)" EXACT [] xref: GO:0045264 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001924 ! proton-transporting ATP synthase complex, coupling factor F(o) relationship: part_of CCO:C0001921 ! plasma membrane proton-transporting ATP synthase complex [Term] id: CCO:C0001926 name: proton-transporting ATP synthase, stator stalk namespace: cellular_component def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core." [PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, stator stalk" EXACT [] xref: GO:0045265 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0001924 ! proton-transporting ATP synthase complex, coupling factor F(o) [Term] id: CCO:C0001927 name: plasma membrane proton-transporting ATP synthase, stator stalk namespace: cellular_component def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core." [GOC:mtg_sensu, PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, stator stalk (sensu Bacteria)" EXACT [] synonym: "proton-transporting ATP synthase, stator stalk (sensu Bacteria)" EXACT [] xref: GO:0045266 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001926 ! proton-transporting ATP synthase, stator stalk relationship: part_of CCO:C0001925 ! plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) [Term] id: CCO:C0001928 name: proton-transporting ATP synthase, catalytic core namespace: cellular_component def: "The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase." [PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, catalytic core" EXACT [] xref: GO:0045267 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) [Term] id: CCO:C0001929 name: plasma membrane proton-transporting ATP synthase, catalytic core namespace: cellular_component def: "The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase." [GOC:mtg_sensu, PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, catalytic core (sensu Bacteria)" EXACT [] synonym: "proton-transporting ATP synthase, catalytic core (sensu Bacteria)" EXACT [] xref: GO:0045268 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001928 ! proton-transporting ATP synthase, catalytic core relationship: part_of CCO:C0001923 ! plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) [Term] id: CCO:C0001930 name: proton-transporting ATP synthase, central stalk namespace: cellular_component def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis." [PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, central stalk" EXACT [] xref: GO:0045269 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0001922 ! proton-transporting ATP synthase complex, catalytic core F(1) [Term] id: CCO:C0001931 name: plasma membrane proton-transporting ATP synthase, central stalk namespace: cellular_component def: "One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis." [GOC:mtg_sensu, PMID:10838056] subset: gosubset_prok synonym: "hydrogen-transporting ATP synthase, central stalk (sensu Bacteria)" EXACT [] synonym: "proton-transporting ATP synthase, central stalk (sensu Bacteria)" EXACT [] xref: GO:0045270 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001930 ! proton-transporting ATP synthase, central stalk relationship: part_of CCO:C0001923 ! plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) [Term] id: CCO:C0001932 name: respiratory chain complex I namespace: cellular_component def: "Respiratory chain complex I is an enzyme of the respiratory chain. It consists of at least 34 polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex." [GOC:jic, ISBN:0716749556] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (ubiquinone) activity ; GO:0008137'. subset: gosubset_prok synonym: "NADH dehydrogenase (ubiquinone) complex" EXACT [] synonym: "NADH dehydrogenase complex (ubiquinone)" EXACT [] synonym: "NADH-Q oxidoreductase complex" EXACT [] xref: GO:0045271 xref: GO:0045279 is_a: CCO:C0002063 ! NADH dehydrogenase complex [Term] id: CCO:C0001933 name: plasma membrane respiratory chain complex I namespace: cellular_component def: "A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone." [GOC:mtg_sensu, ISBN:0198547684] subset: gosubset_prok synonym: "NADH dehydrogenase (ubiquinone) complex (sensu Bacteria)" EXACT [] synonym: "respiratory chain complex I (sensu Bacteria)" EXACT [] xref: GO:0045272 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001932 ! respiratory chain complex I [Term] id: CCO:C0001934 name: respiratory chain complex II namespace: cellular_component def: "A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain." [ISBN:0198547684] subset: goslim_pir subset: gosubset_prok xref: GO:0045273 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001935 name: plasma membrane respiratory chain complex II namespace: cellular_component def: "A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain." [GOC:mtg_sensu, ISBN:0198547684] subset: gosubset_prok synonym: "respiratory chain complex II (sensu Bacteria)" EXACT [] xref: GO:0045274 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001934 ! respiratory chain complex II [Term] id: CCO:C0001936 name: respiratory chain complex III namespace: cellular_component def: "A part of the respiratory chain, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1." [ISBN:0198547684] subset: goslim_pir subset: gosubset_prok synonym: "ubiquinol-cytochrome c oxidoreductase complex" EXACT [] synonym: "ubiquinol-cytochrome-c reductase complex" EXACT [] xref: GO:0045275 xref: GO:0045285 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001937 name: plasma membrane respiratory chain complex III namespace: cellular_component def: "A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1." [GOC:mtg_sensu, ISBN:0198547684] subset: gosubset_prok synonym: "plasma membrane ubiquinol-cytochrome-c reductase complex" EXACT [] synonym: "respiratory chain complex III (sensu Bacteria)" EXACT [] synonym: "ubiquinol-cytochrome c oxidoreductase complex (sensu Bacteria)" EXACT [] synonym: "ubiquinol-cytochrome-c reductase complex (sensu Bacteria)" EXACT [] xref: GO:0045276 xref: GO:0045286 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001936 ! respiratory chain complex III [Term] id: CCO:C0001938 name: respiratory chain complex IV namespace: cellular_component def: "A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2)." [ISBN:0198547684] subset: goslim_pir subset: gosubset_prok synonym: "cytochrome c oxidase complex" EXACT [] xref: GO:0045277 xref: GO:0045287 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001939 name: plasma membrane respiratory chain complex IV namespace: cellular_component def: "A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2)." [GOC:mtg_sensu, ISBN:0198547684] subset: gosubset_prok synonym: "cytochrome c oxidase complex (sensu Bacteria)" EXACT [] synonym: "respiratory chain complex IV (sensu Bacteria)" EXACT [] xref: GO:0045278 xref: GO:0045288 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001938 ! respiratory chain complex IV [Term] id: CCO:C0001941 name: succinate dehydrogenase complex namespace: cellular_component def: "A multimeric complex which consists of flavoprotein (subunit A ; InterPro:003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones." [GOC:kd, InterPro:IPR000701] subset: gosubset_prok xref: GO:0045281 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0001934 ! respiratory chain complex II [Term] id: CCO:C0001942 name: plasma membrane succinate dehydrogenase complex namespace: cellular_component def: "A multimeric complex which consists of flavoprotein (subunit A ; InterPro:003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones." [GOC:kd, GOC:mtg_sensu, InterPro:IPR000701] subset: gosubset_prok synonym: "succinate dehydrogenase complex (sensu Bacteria)" EXACT [] xref: GO:0045282 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001941 ! succinate dehydrogenase complex relationship: part_of CCO:C0001935 ! plasma membrane respiratory chain complex II [Term] id: CCO:C0001943 name: fumarate reductase complex namespace: cellular_component def: "A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:003510; InterPro:004224) and D (InterPro:003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone))." [InterPro:IPR003418, InterPro:IPR004224] comment: See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'. subset: gosubset_prok xref: GO:0045283 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0001934 ! respiratory chain complex II [Term] id: CCO:C0001944 name: plasma membrane fumarate reductase complex namespace: cellular_component def: "A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:003510; InterPro:00224) and D (InterPro:003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2)." [GOC:mtg_sensu, InterPro:IPR003418, InterPro:IPR004224] comment: See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'. subset: gosubset_prok synonym: "fumarate reductase complex (sensu Bacteria)" EXACT [] xref: GO:0045284 is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001943 ! fumarate reductase complex relationship: part_of CCO:C0001935 ! plasma membrane respiratory chain complex II [Term] id: CCO:C0001945 name: mRNA editing complex namespace: cellular_component def: "A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes." [http://www.ejbiotechnology.info/content/vol1/issue1/full/4/, PMID:11564867, PMID:12139607] subset: goslim_pir synonym: "editosome" EXACT [] xref: GO:0045293 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0001946 name: tubulin complex namespace: cellular_component def: "A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly." [http://cancerweb.ncl.ac.uk/, ISBN:0716731363] xref: GO:0045298 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0039671 ! TCTP_HUMAN-Phosphoserine46 relationship: location_of CCO:B0071135 ! TAU_HUMAN-Phosphothreonine111 relationship: part_of CCO:C0000434 ! microtubule [Term] id: CCO:C0001947 name: chloroplast proton-transporting ATP synthase complex namespace: cellular_component def: "A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation." [GOC:mtg_sensu, GOC:pj, ISBN:0716743663] synonym: "chloroplast hydrogen-translocating F-type ATPase complex" EXACT [] synonym: "chloroplast proton-transporting F-type ATPase complex" EXACT [] synonym: "hydrogen-translocating F-type ATPase complex (sensu Viridiplantae)" EXACT [] xref: GO:0045320 is_a: CCO:C0001853 ! chloroplast part is_a: CCO:C0001855 ! thylakoid part is_a: CCO:C0001920 ! proton-transporting ATP synthase complex relationship: part_of CCO:C0000663 ! chloroplast thylakoid membrane [Term] id: CCO:C0001948 name: interleukin-1 receptor complex namespace: cellular_component def: "Complex that binds interleukin-1; comprises an alpha and a beta subunit." [GOC:mah, InterPro:IPR004075] xref: GO:0045323 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0005273 ! TOLIP_HUMAN relationship: location_of CCO:B0005985 ! TRIP6_HUMAN relationship: location_of CCO:B0067152 ! IRAK1_HUMAN-Phosphoserine568 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001949 name: clathrin-coated endocytic vesicle namespace: cellular_component def: "A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance." [GOC:go_curators] xref: GO:0045334 is_a: CCO:C0000981 ! clathrin-coated vesicle is_a: CCO:C0000983 ! endocytic vesicle relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0056054 ! RAB35_HUMAN [Term] id: CCO:C0001950 name: phagocytic vesicle namespace: cellular_component def: "A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "phagosome" EXACT [] xref: GO:0045335 is_a: CCO:C0000983 ! endocytic vesicle relationship: location_of CCO:B0001581 ! COR1A_HUMAN relationship: location_of CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0070985 ! STX12_HUMAN-Phosphoserine142 [Term] id: CCO:C0001951 name: clathrin-coated phagocytic vesicle namespace: cellular_component def: "A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "clathrin-coated phagosome" EXACT [] xref: GO:0045336 is_a: CCO:C0001949 ! clathrin-coated endocytic vesicle is_a: CCO:C0001950 ! phagocytic vesicle [Term] id: CCO:C0001952 name: pole plasm namespace: cellular_component def: "Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo." [GOC:kva, http://cancerweb.ncl.ac.uk/] synonym: "germ plasm" NARROW [] synonym: "polar plasm" EXACT [] xref: GO:0045495 is_a: CCO:C0000324 ! cytoplasm [Term] id: CCO:C0001953 name: dosage compensation complex namespace: cellular_component def: "A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes." [GOC:kva, GOC:mah] subset: goslim_pir xref: GO:0046536 is_a: CCO:C0001847 ! nuclear part relationship: part_of CCO:C0000130 ! sex chromosome [Term] id: CCO:C0001954 name: U4/U6 x U5 tri-snRNP complex namespace: cellular_component def: "A complex composed of three small nuclear ribonucleoproteins, snRNP U4, snRNP U6 and snRNP U5." [PMID:11867543] synonym: "U4/U6 . U5 snRNP complex" EXACT [] xref: GO:0046540 is_a: CCO:C0001022 ! small nuclear ribonucleoprotein complex [Term] id: CCO:C0001955 name: intercellular canaliculus namespace: cellular_component def: "An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0046581 is_a: CCO:C0000463 ! intercellular junction relationship: location_of CCO:B0038734 ! DPP4_HUMAN [Term] id: CCO:C0001956 name: lysosomal proton-transporting V-type ATPase, V0 domain namespace: cellular_component def: "The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane." [GOC:mah] synonym: "lysosomal hydrogen ion-transporting ATPase V0 domain" EXACT [] xref: GO:0046610 is_a: CCO:C0000036 ! vacuolar proton-transporting V-type ATPase, V0 domain relationship: part_of CCO:C0001957 ! lysosomal proton-transporting V-type ATPase complex [Term] id: CCO:C0001957 name: lysosomal proton-transporting V-type ATPase complex namespace: cellular_component def: "A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen." [GOC:mah, ISBN:0716743663, PMID:16449553] synonym: "lysosomal hydrogen-translocating V-type ATPase complex" EXACT [] synonym: "lysosomal membrane hydrogen-transporting ATPase" BROAD [] xref: GO:0046611 is_a: CCO:C0000793 ! vacuolar proton-transporting V-type ATPase complex relationship: part_of CCO:C0000348 ! lysosomal membrane [Term] id: CCO:C0001958 name: lysosomal proton-transporting V-type ATPase, V1 domain namespace: cellular_component def: "The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane." [GOC:mah] synonym: "lysosomal hydrogen ion-transporting ATPase V1 domain" EXACT [] xref: GO:0046612 is_a: CCO:C0000037 ! vacuolar proton-transporting V-type ATPase, V1 domain relationship: part_of CCO:C0001957 ! lysosomal proton-transporting V-type ATPase complex [Term] id: CCO:C0001959 name: anchored to plasma membrane namespace: cellular_component def: "Tethered to the plasma membrane by a covalently attached anchor, such as a lipid moiety, that is embedded in the membrane. When used to describe a protein, indicates that the peptide sequence does not span the membrane." [GOC:mah] synonym: "plasma membrane, GPI-anchored" NARROW [] xref: GO:0046658 is_a: CCO:C0001149 ! anchored to membrane is_a: CCO:C0001150 ! intrinsic to plasma membrane relationship: location_of CCO:B0001672 ! GAS1_HUMAN relationship: location_of CCO:B0054811 ! BY55_HUMAN relationship: location_of CCO:B0056863 ! RGMB_HUMAN relationship: location_of CCO:B0062941 ! NTNG2_HUMAN [Term] id: CCO:C0001960 name: intracellular canaliculus namespace: cellular_component def: "A narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary", PMID:10700045] xref: GO:0046691 is_a: CCO:C0001877 ! plasma membrane part relationship: part_of CCO:C0000781 ! apical plasma membrane [Term] id: CCO:C0001961 name: SLIK (SAGA-like) complex namespace: cellular_component def: "A protein complex similar to the SAGA complex but with a smaller form of Spt7 and no Spt8. Although little is known about the SLIK complex, evidence suggests involvement of the general amino acid control pathway." [PMID:12101232, PMID:12186975] comment: See also the cellular component term 'SAGA complex ; GO:0000124'. synonym: "SAGA (alt) complex" EXACT [] synonym: "SALSA complex" EXACT [] synonym: "SLIK/SALSA complex" EXACT [] xref: GO:0046695 is_a: CCO:C0000011 ! histone acetyltransferase complex [Term] id: CCO:C0001962 name: lipopolysaccharide receptor complex namespace: cellular_component def: "A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated." [PMID:11706042] comment: Note that this term should not be used to refer to CD14 alone, but the multiprotein receptor complex that it is part of. synonym: "LPS receptor complex" EXACT [] xref: GO:0046696 is_a: CCO:C0000767 ! integral to membrane is_a: CCO:C0001751 ! receptor complex relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0022071 ! TLR4_HUMAN [Term] id: CCO:C0001963 name: capsomere namespace: cellular_component def: "Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "capsomer" EXACT [] xref: GO:0046727 is_a: CCO:C0001842 ! virion part relationship: part_of CCO:C0000867 ! viral capsid [Term] id: CCO:C0001964 name: viral procapsid namespace: cellular_component def: "A stable empty viral capsid produced during the assembly of viruses." [ISBN:0072370319, ISBN:1555811272] xref: GO:0046729 is_a: CCO:C0001842 ! virion part [Term] id: CCO:C0001965 name: viral portal complex namespace: cellular_component def: "A multimeric ring of proteins through which the DNA enters and exits the viral capsid." [PMID:11602732] xref: GO:0046798 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001842 ! virion part relationship: part_of CCO:C0000867 ! viral capsid [Term] id: CCO:C0001966 name: viral scaffold namespace: cellular_component def: "A complex of proteins that form a scaffold around which the viral capsid is constructed." [ISBN:0072370319] xref: GO:0046806 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001842 ! virion part relationship: part_of CCO:C0000867 ! viral capsid [Term] id: CCO:C0001967 name: assemblon namespace: cellular_component def: "Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously." [PMID:8676489] xref: GO:0046808 is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001968 name: replication compartment namespace: cellular_component def: "Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously." [PMID:9499108] xref: GO:0046809 is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001969 name: virion transport vesicle namespace: cellular_component def: "A vesicle used to transport the partial or complete virion between cellular compartments." [PMID:7933124] xref: GO:0046816 is_a: CCO:C0001374 ! vesicle is_a: CCO:C0002129 ! intracellular membrane-bounded organelle [Term] id: CCO:C0001970 name: dense nuclear body namespace: cellular_component def: "A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously." [PMID:10233976] xref: GO:0046818 is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0001971 name: extrachromosomal DNA namespace: cellular_component def: "DNA structures that are not part of a chromosome." [GOC:ai] subset: gosubset_prok xref: GO:0046821 is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001972 name: chlorosome namespace: cellular_component def: "A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:14729689, PMID:15298919] subset: gosubset_prok xref: GO:0046858 is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001973 name: hydrogenosomal membrane namespace: cellular_component def: "The lipid bilayer surrounding a hydrogenosome." [GOC:ai] synonym: "hydrogenosome membrane" EXACT [] xref: GO:0046859 is_a: CCO:C0001127 ! organelle membrane is_a: CCO:C0001863 ! cytoplasmic part relationship: part_of CCO:C0001647 ! hydrogenosome [Term] id: CCO:C0001974 name: glycosome membrane namespace: cellular_component def: "The lipid bilayer surrounding a glycosome." [GOC:ai] xref: GO:0046860 is_a: CCO:C0001127 ! organelle membrane relationship: part_of CCO:C0000914 ! glycosome [Term] id: CCO:C0001975 name: glyoxysomal membrane namespace: cellular_component def: "The lipid bilayer surrounding a glyoxysome." [GOC:ai] synonym: "glyoxysome membrane" EXACT [] xref: GO:0046861 is_a: CCO:C0001341 ! microbody membrane is_a: CCO:C0001857 ! microbody part relationship: part_of CCO:C0000643 ! glyoxysome [Term] id: CCO:C0001976 name: chromoplast membrane namespace: cellular_component def: "Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope." [GOC:ai, GOC:mah] xref: GO:0046862 is_a: CCO:C0001634 ! plastid membrane relationship: part_of CCO:C0001336 ! chromoplast envelope [Term] id: CCO:C0001977 name: mesosome namespace: cellular_component def: "An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins." [http://cancerweb.ncl.ac.uk/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0716731363986] subset: gosubset_prok xref: GO:0046868 is_a: CCO:C0001877 ! plasma membrane part [Term] id: CCO:C0001978 name: pore complex namespace: cellular_component def: "Any small opening in a membrane that allows the passage of gases and/or liquids." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "channel-forming toxin activity" RELATED [] synonym: "pore" EXACT [] synonym: "pore-forming toxin activity" RELATED [] xref: GO:0046930 is_a: CCO:C0000767 ! integral to membrane relationship: location_of CCO:B0014593 ! VDAC1_HUMAN-Phosphoserine13 relationship: location_of CCO:B0021718 ! NUP62_HUMAN [Term] id: CCO:C0001979 name: apoplast namespace: cellular_component def: "The protoplasts of cells in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it." [GOC:jic] xref: GO:0048046 is_a: CCO:C0000201 ! extracellular region [Term] id: CCO:C0001980 name: activin receptor complex namespace: cellular_component def: "Activin receptors can be type I or type II and are cell surface transmembrane receptors with serine/threonine activity." [GOC:jic, ISBN:0121551423] xref: GO:0048179 is_a: CCO:C0001751 ! receptor complex is_a: CCO:C0001877 ! plasma membrane part relationship: location_of CCO:B0020368 ! ACV1C_HUMAN relationship: location_of CCO:B0035985 ! ACVR1_HUMAN-Phosphoserine501 relationship: part_of CCO:C0000445 ! integral to plasma membrane [Term] id: CCO:C0001981 name: activin complex namespace: cellular_component def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit." [GOC:go_curators, http://www.mercksource.com, http://www.stedmans.com/] comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'. subset: goslim_pir xref: GO:0048180 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001840 ! extracellular region part relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0001982 name: activin AB complex namespace: cellular_component def: "A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B." [GOC:go_curators, http://www.mercksource.com, http://www.stedmans.com/] comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'. synonym: "inhibin beta-A" NARROW [] synonym: "inhibin beta-B" NARROW [] xref: GO:0048183 is_a: CCO:C0001981 ! activin complex [Term] id: CCO:C0001983 name: COMPASS complex namespace: cellular_component def: "A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p." [PMID:11687631, PMID:11805083] synonym: "Set1 complex" NARROW [] synonym: "Set1C" NARROW [] xref: GO:0048188 is_a: CCO:C0000806 ! chromatin remodeling complex is_a: CCO:C0001616 ! histone methyltransferase complex [Term] id: CCO:C0001984 name: Lid2 complex namespace: cellular_component def: "A protein complex that is thought to be involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid1p, Ash2p, Ecm5p, Snt2p, and Sdc1p." [PMID:12488447] xref: GO:0048189 is_a: CCO:C0000806 ! chromatin remodeling complex [Term] id: CCO:C0001985 name: middle lamella-containing extracellular matrix namespace: cellular_component def: "The matrix external to the cell, composed of the cell wall and middle lamella." [GOC:jic, GOC:mtg_sensu, http://cancerweb.ncl.ac.uk] comment: Note that this term does not have 'extracellular region ; GO:0005576' as a parent because in plants the extracellular matrix is considered part of the cell. subset: goslim_pir synonym: "extracellular matrix (sensu Magnoliophyta)" EXACT [] xref: GO:0048196 is_a: CCO:C0000999 ! external encapsulating structure is_a: CCO:C0001109 ! extracellular matrix [Term] id: CCO:C0001986 name: pectic matrix namespace: cellular_component def: "The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls." [GOC:jic, http://cancerweb.ncl.ac.uk] xref: GO:0048217 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0000658 ! primary cell wall relationship: part_of CCO:C0000659 ! secondary cell wall [Term] id: CCO:C0001987 name: glycoprotein network namespace: cellular_component def: "A network of glycoproteins; proteins with covalently attached sugar units, either bonded via the hydroxyl group of serine or threonine (O glycosylated) or through the amino terminal of asparagine (N glycosylated)." [GOC:jic, http://cancerweb.ncl.ac.uk] subset: gosubset_prok synonym: "extensin" EXACT [] xref: GO:0048222 is_a: CCO:C0001839 ! extracellular matrix part is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0000658 ! primary cell wall [Term] id: CCO:C0001988 name: hemicellulose network namespace: cellular_component def: "Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan." [GOC:jic, http://cancerweb.ncl.ac.uk] xref: GO:0048223 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0000658 ! primary cell wall relationship: part_of CCO:C0000659 ! secondary cell wall [Term] id: CCO:C0001989 name: lignin network namespace: cellular_component def: "A network composed of lignin; a complex polymer of phenylpropanoid subunits, laid down in the walls of plant cells such as xylem vessels and sclerenchyma. It imparts considerable strength to the wall and also protects it against degradation by microorganisms. It is also laid down as a defence reaction against pathogenic attack, as part of the hypersensitive response of plants." [GOC:jic, http://cancerweb.ncl.ac.uk] xref: GO:0048224 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0000659 ! secondary cell wall [Term] id: CCO:C0001990 name: suberin network namespace: cellular_component def: "Fatty substance, containing long chain fatty acids and fatty esters, found in the cell walls of cork cells (phellem) in higher plants. Renders the cell wall impervious to water." [GOC:jic, http://cancerweb.ncl.ac.uk] xref: GO:0048225 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0000659 ! secondary cell wall [Term] id: CCO:C0001991 name: Casparian strip namespace: cellular_component def: "Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants." [GOC:jic, http://cancerweb.ncl.ac.uk] xref: GO:0048226 is_a: CCO:C0001845 ! cell wall part relationship: part_of CCO:C0000659 ! secondary cell wall [Term] id: CCO:C0001992 name: rough endoplasmic reticulum lumen namespace: cellular_component def: "The volume enclosed by the membranes of the rough endoplasmic reticulum." [GOC:jic] synonym: "rough ER lumen" EXACT [] xref: GO:0048237 is_a: CCO:C0000369 ! endoplasmic reticulum lumen relationship: part_of CCO:C0000372 ! rough endoplasmic reticulum [Term] id: CCO:C0001993 name: smooth endoplasmic reticulum lumen namespace: cellular_component def: "The volume enclosed by the membranes of the smooth endoplasmic reticulum." [GOC:jic] synonym: "smooth ER lumen" EXACT [] xref: GO:0048238 is_a: CCO:C0000369 ! endoplasmic reticulum lumen relationship: part_of CCO:C0000371 ! smooth endoplasmic reticulum [Term] id: CCO:C0001994 name: methionine adenosyltransferase complex namespace: cellular_component def: "A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules." [EC:2.5.1.6, GOC:jic, PMID:10644686] synonym: "MAT complex" EXACT [] xref: GO:0048269 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001995 name: primary endosperm nucleus namespace: cellular_component def: "Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac." [ISBN:0471245208] xref: GO:0048353 is_a: CCO:C0000252 ! nucleus [Term] id: CCO:C0001996 name: perinuclear region of cytoplasm namespace: cellular_component def: "Cytoplasm situated near, or occurring around, the nucleus." [GOC:jic] comment: Note that this term should not be confused with the cellular component term 'nuclear membrane lumen ; GO:0005641', which has the synonym 'perinuclear space'. xref: GO:0048471 is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0001397 ! ACTN4_HUMAN relationship: location_of CCO:B0001440 ! DCTN3_HUMAN relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0001592 ! MERL_HUMAN relationship: location_of CCO:B0001618 ! LIS1_HUMAN relationship: location_of CCO:B0005181 ! UBQL1_HUMAN relationship: location_of CCO:B0005473 ! GTR4_HUMAN relationship: location_of CCO:B0005519 ! SET_HUMAN relationship: location_of CCO:B0005583 ! SC23A_HUMAN relationship: location_of CCO:B0005599 ! KINH_HUMAN relationship: location_of CCO:B0005755 ! LPPRC_HUMAN relationship: location_of CCO:B0005816 ! ATX10_HUMAN relationship: location_of CCO:B0005947 ! PICK1_HUMAN relationship: location_of CCO:B0005967 ! LAMB1_HUMAN relationship: location_of CCO:B0006227 ! PRKN2_HUMAN relationship: location_of CCO:B0010365 ! 1433B_HUMAN-Phosphoserine186 relationship: location_of CCO:B0010509 ! AN32A_HUMAN-Phosphoserine158 relationship: location_of CCO:B0010888 ! CADH1_HUMAN-Phosphoserine838 relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0011441 ! DC1I1_HUMAN-Phosphoserine635 relationship: location_of CCO:B0011552 ! DNJB6_HUMAN-Phosphoserine277 relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0013200 ! NOG1_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0014015 ! SEPT9_HUMAN-Phosphoserine89 relationship: location_of CCO:B0022071 ! TLR4_HUMAN relationship: location_of CCO:B0031342 ! MYO16_HUMAN-Phosphotyrosine1432 relationship: location_of CCO:B0032858 ! TAF10_HUMAN-N6-methyllysine189 relationship: location_of CCO:B0037573 ! CYFP1_HUMAN relationship: location_of CCO:B0039548 ! MYO9B_HUMAN-Phosphoserine1993 relationship: location_of CCO:B0039610 ! RAGP1_HUMAN-Phosphoserine428 relationship: location_of CCO:B0040093 ! SYT5_HUMAN relationship: location_of CCO:B0049019 ! IGHM_HUMAN relationship: location_of CCO:B0050294 ! HMGB2_HUMAN relationship: location_of CCO:B0054484 ! TNF12_HUMAN relationship: location_of CCO:B0054701 ! TPPP_HUMAN relationship: location_of CCO:B0054980 ! CLUS_HUMAN relationship: location_of CCO:B0055025 ! ENPL_HUMAN relationship: location_of CCO:B0055143 ! ACES_HUMAN relationship: location_of CCO:B0055194 ! APEX1_HUMAN relationship: location_of CCO:B0055732 ! ATP7A_HUMAN relationship: location_of CCO:B0057344 ! HUNIN_HUMAN relationship: location_of CCO:B0057450 ! AGGF1_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058423 ! P2RX4_HUMAN relationship: location_of CCO:B0058862 ! ISK5_HUMAN relationship: location_of CCO:B0059029 ! VAPA_HUMAN relationship: location_of CCO:B0062986 ! VPS4A_HUMAN relationship: location_of CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 relationship: location_of CCO:B0064145 ! CD2AP_HUMAN-Phosphoserine224 relationship: location_of CCO:B0066115 ! FAF1_HUMAN-Phosphothreonine580 relationship: location_of CCO:B0068994 ! OREX_HUMAN-Methionine amide97 relationship: location_of CCO:B0069667 ! RAB14_HUMAN-Phosphothreonine98 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 relationship: location_of CCO:B0071476 ! TPD53_HUMAN-Phosphoserine149 relationship: location_of CCO:B0071600 ! TSC2_HUMAN-Phosphoserine1337 [Term] id: CCO:C0001997 name: coated membrane namespace: cellular_component def: "A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes." [GOC:jic] xref: GO:0048475 is_a: CCO:C0000766 ! membrane [Term] id: CCO:C0001998 name: Holliday junction resolvase complex namespace: cellular_component def: "A protein complex that mediates the conversion of a Holliday junction into two separate duplex DNA molecules; the complex includes a single- or multisubunit helicase that catalyzes the extension of heteroduplex DNA by branch migration and a nuclease that resolves the junction by nucleolytic cleavage." [PMID:11207366, PMID:12374758] subset: goslim_pir synonym: "Mus81-Eme1 complex" NARROW [] synonym: "resolvasome" EXACT [PMID:11207366] xref: GO:0048476 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0001999 name: ribulose bisphosphate carboxylase complex namespace: cellular_component def: "A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate." [GOC:mlg] subset: goslim_pir subset: gosubset_prok synonym: "RubisCO complex" EXACT [] xref: GO:0048492 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0002000 name: plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex namespace: cellular_component def: "A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate." [GOC:mlg, GOC:mtg_sensu] subset: gosubset_prok synonym: "plasma membrane ribulose bisphosphate carboxylase complex" EXACT [] synonym: "ribulose bisphosphate carboxylase complex (sensu Cyanobacteria)" EXACT [] synonym: "RubisCO complex (sensu Cyanobacteria)" EXACT [] xref: GO:0048493 is_a: CCO:C0001855 ! thylakoid part is_a: CCO:C0001877 ! plasma membrane part is_a: CCO:C0001999 ! ribulose bisphosphate carboxylase complex relationship: part_of CCO:C0000942 ! plasma membrane-derived thylakoid [Term] id: CCO:C0002001 name: chromatophore ribulose bisphosphate carboxylase complex namespace: cellular_component def: "A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate." [GOC:mlg, GOC:mtg_sensu] subset: gosubset_prok synonym: "ribulose bisphosphate carboxylase complex (sensu Proteobacteria, Chloroflexaceae and Chlorobiaceae)" EXACT [] synonym: "RubisCO complex (sensu Proteobacteria)" EXACT [] xref: GO:0048494 is_a: CCO:C0001688 ! chromatophore is_a: CCO:C0001999 ! ribulose bisphosphate carboxylase complex [Term] id: CCO:C0002002 name: signal recognition particle namespace: cellular_component def: "A complex of protein and RNA which facilitates translocation of proteins across membranes." [GOC:mlg] subset: goslim_pir subset: gosubset_prok xref: GO:0048500 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0029881 ! O15302_HUMAN relationship: location_of CCO:B0051561 ! Q659G3_HUMAN relationship: location_of CCO:B0051562 ! SRP09_HUMAN relationship: location_of CCO:B0051564 ! Q6NVX0_HUMAN relationship: location_of CCO:B0055316 ! SRP14_HUMAN [Term] id: CCO:C0002003 name: signal recognition particle, plasma membrane targeting namespace: cellular_component def: "A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane." [GOC:mlg, GOC:mtg_sensu] subset: gosubset_prok synonym: "signal recognition particle (sensu Bacteria and Archaea)" EXACT [] xref: GO:0048501 is_a: CCO:C0002002 ! signal recognition particle [Term] id: CCO:C0002004 name: generative cell nucleus namespace: cellular_component def: "The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells." [GOC:tair_curators] synonym: "male germ cell nucleus (sensu Magnoliophyta)" EXACT [] synonym: "sperm cell nucleus (sensu Magnoliophyta)" RELATED [] xref: GO:0048555 is_a: CCO:C0000252 ! nucleus [Term] id: CCO:C0002005 name: microsporocyte nucleus namespace: cellular_component def: "The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte." [GOC:tair_curators, ISBN:047186840X] synonym: "microspore mother cell nucleus" EXACT [] synonym: "pollen mother cell nucleus" EXACT [] xref: GO:0043074 xref: GO:0048556 is_a: CCO:C0000252 ! nucleus [Term] id: CCO:C0002006 name: pigment granule namespace: cellular_component def: "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." [GOC:jic, GOC:mh] xref: GO:0048770 is_a: CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0002007 name: presynaptic active zone namespace: cellular_component def: "A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, synaptic vesicles, and a specialized cortical cytoskeletal matrix." [GOC:dh, GOC:dl, GOC:ef, GOC:jic, PMID:3152289] xref: GO:0048786 is_a: CCO:C0001875 ! synapse part relationship: location_of CCO:B0059143 ! NUFP1_HUMAN [Term] id: CCO:C0002008 name: presynaptic active zone membrane namespace: cellular_component def: "The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters." [PMID:12812759, PMID:12923177, PMID:3152289] synonym: "active zone presynaptic plasma membrane" EXACT [] xref: GO:0048787 is_a: CCO:C0001695 ! presynaptic membrane relationship: location_of CCO:B0042227 ! GRM7_HUMAN relationship: part_of CCO:C0002007 ! presynaptic active zone [Term] id: CCO:C0002009 name: presynaptic cytoskeletal matrix assembled at active zones namespace: cellular_component def: "The specialized cytoskeletal matrix assembled at the active zones of the presynaptic nerve terminal. The cytoskeletal matrix is a proteinaceous structure involved in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. The cytomatrix protein exclusively assembled at active zones, is thought to form a molecular scaffold that organizes neurotransmitter release sites." [GOC:dh, GOC:dl, GOC:ef, GOC:jic, PMID:10944438] synonym: "CAZ" NARROW [] synonym: "presynaptic cytomatrix assembled at active zones" EXACT [] xref: GO:0048788 is_a: CCO:C0001055 ! cortical cytoskeleton is_a: CCO:C0001875 ! synapse part relationship: part_of CCO:C0002007 ! presynaptic active zone [Term] id: CCO:C0002010 name: secondary cell septum namespace: cellular_component def: "Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum." [GOC:mtg_sensu, PMID:15194814] synonym: "secondary cell septum (sensu Fungi)" EXACT [] synonym: "secondary septum (sensu Fungi)" EXACT [] xref: GO:0051077 is_a: CCO:C0001008 ! cell septum [Term] id: CCO:C0002011 name: spindle midzone namespace: cellular_component def: "The area in the center of the spindle where the spindle microtubules from opposite poles overlap." [GOC:ai, PMID:15296749] synonym: "spindle equator" EXACT [] xref: GO:0051233 is_a: CCO:C0001849 ! cytoskeletal part relationship: location_of CCO:B0010603 ! ARL8B_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035987 ! BUB1B_HUMAN-Phosphothreonine54 relationship: location_of CCO:B0058166 ! ARL8A_HUMAN relationship: part_of CCO:C0000388 ! spindle [Term] id: CCO:C0002012 name: cell cortex of cell tip namespace: cellular_component def: "The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell." [GOC:ai] synonym: "cell cortex of cell end" EXACT [] xref: GO:0051285 is_a: CCO:C0001867 ! cell cortex part relationship: part_of CCO:C0002013 ! cell tip [Term] id: CCO:C0002013 name: cell tip namespace: cellular_component def: "The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth may occur." [GOC:ai, GOC:vw] synonym: "cell end" EXACT [] xref: GO:0051286 is_a: CCO:C0001007 ! site of polarized growth [Term] id: CCO:C0002014 name: cortical microtubule namespace: cellular_component def: "Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol." [GOC:mtg_sensu] xref: GO:0055028 is_a: CCO:C0000439 ! cytoplasmic microtubule relationship: part_of CCO:C0001096 ! cortical microtubule cytoskeleton [Term] id: CCO:C0002015 name: nuclear DNA-directed RNA polymerase complex namespace: cellular_component def: "A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity." [GOC:mtg_sensu] xref: GO:0055029 is_a: CCO:C0000085 ! DNA-directed RNA polymerase complex [Term] id: CCO:C0002016 name: peptidoglycan-based spore wall namespace: cellular_component def: "A spore wall consisting of a peptidoglycan-containing inner layer (the spore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer." [GOC:mtg_sensu, PMID:15035041] synonym: "spore wall (sensu Bacteria)" EXACT [] xref: GO:0055030 is_a: CCO:C0001137 ! spore wall [Term] id: CCO:C0002017 name: gamma-tubulin large complex, equatorial microtubule organizing center namespace: cellular_component def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at equatorial microtubule organizing centers." [GOC:mtg_sensu] synonym: "gamma-tubulin large complex, eMTOC" EXACT [] synonym: "gamma-tubulin large complex, equatorial microtubule organizing centre" EXACT [] xref: GO:0055031 is_a: CCO:C0000150 ! gamma-tubulin large complex relationship: part_of CCO:C0000145 ! equatorial microtubule organizing center [Term] id: CCO:C0002018 name: gamma-tubulin large complex, spindle pole body namespace: cellular_component def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the spindle pole body." [GOC:mtg_sensu] xref: GO:0055032 is_a: CCO:C0000150 ! gamma-tubulin large complex relationship: part_of CCO:C0000386 ! spindle pole body [Term] id: CCO:C0002019 name: gamma-tubulin large complex, interphase microtubule organizing center namespace: cellular_component def: "A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at interphase microtubule organizing centers." [GOC:mtg_sensu] synonym: "gamma-tubulin large complex, iMTOC" EXACT [] synonym: "gamma-tubulin large complex, interphase microtubule organizing centre" EXACT [] xref: GO:0055033 is_a: CCO:C0000150 ! gamma-tubulin large complex relationship: part_of CCO:C0001113 ! interphase microtubule organizing center [Term] id: CCO:C0002020 name: plastid thylakoid membrane namespace: cellular_component def: "The lipid bilayer membrane of any thylakoid within a plastid." [GOC:jic, GOC:rph] xref: GO:0055035 is_a: CCO:C0001684 ! thylakoid membrane is_a: CCO:C0001854 ! plastid part relationship: part_of CCO:C0001368 ! plastid thylakoid [Term] id: CCO:C0002021 name: virion membrane namespace: cellular_component def: "The lipid bilayer surrounding a virion." [GOC:jic, GOC:rph, PMID:213106] xref: GO:0055036 is_a: CCO:C0001842 ! virion part [Term] id: CCO:C0002022 name: recycling endosome namespace: cellular_component def: "Organelle consisting of networks of 60nm tubules organized around the microtubule organizing centre in some cell types. They transport receptors from late endosomes back to the plasma membrane for recycling and are also involved in membrane trafficking." [GOC:jic, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101] xref: GO:0055037 is_a: CCO:C0000351 ! endosome relationship: location_of CCO:B0001474 ! TNFA_HUMAN relationship: location_of CCO:B0063285 ! RABE1_HUMAN [Term] id: CCO:C0002023 name: recycling endosome membrane namespace: cellular_component def: "The lipid bilayer surrounding a recycling endosome." [GOC:jic, GOC:rph, PMID:10930469, PMID:15601896, PMID:16246101] xref: GO:0055038 is_a: CCO:C0000713 ! endosome membrane is_a: CCO:C0002022 ! recycling endosome relationship: location_of CCO:B0005979 ! RFIP4_HUMAN relationship: location_of CCO:B0038438 ! RB11A_HUMAN relationship: location_of CCO:B0040093 ! SYT5_HUMAN [Term] id: CCO:C0002024 name: trichocyst namespace: cellular_component def: "A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in \"nets\" to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft." [GOC:jic, GOC:rph, http://www.iscid.org/encyclopedia/, PMID:3667715] xref: GO:0055039 is_a: CCO:C0002131 ! extracellular non-membrane-bounded organelle [Term] id: CCO:C0002025 name: periplasmic flagellum namespace: cellular_component def: "Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella." [GOC:jic, GOC:rph, PMID:15175283, PMID:1624463] xref: GO:0055040 is_a: CCO:C0000561 ! flagellin-based flagellum relationship: part_of CCO:C0001662 ! periplasmic space [Term] id: CCO:C0002026 name: symplast namespace: cellular_component def: "The interconnected protoplasts of a plant. The interconnections occur via the plasmodesmata." [GOC:mtg_sensu] subset: goslim_pir xref: GO:0055044 is_a: CCO:C0000200 ! cellular_component [Term] id: CCO:C0002027 name: ATP-binding cassette (ABC) transporter complex, integrated substrate binding namespace: cellular_component def: "A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a \"half transporter\". Two \"half-transporters\" come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [GOC:mlg, GOC:mtg_sensu] xref: GO:0055051 is_a: CCO:C0001725 ! ATP-binding cassette (ABC) transporter complex [Term] id: CCO:C0002028 name: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing namespace: cellular_component def: "A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP." [GOC:mlg, GOC:mtg_sensu] xref: GO:0055052 is_a: CCO:C0001725 ! ATP-binding cassette (ABC) transporter complex [Term] id: CCO:C0002029 name: Ski complex namespace: cellular_component def: "A heterotrimeric protein complex that regulates RNA degradation by the exosome complex." [GOC:mcc, PMID:10744028, PMID:15703439, PMID:16043509] xref: GO:0055087 is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0002030 name: neurofilament cytoskeleton namespace: cellular_component def: "Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons." [GOC:dph] xref: GO:0060053 is_a: CCO:C0001888 ! intermediate filament cytoskeleton [Term] id: CCO:C0002031 name: excitatory synapse namespace: cellular_component def: "A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell." [GOC:dph, GOC:ef] xref: GO:0060076 is_a: CCO:C0001900 ! synapse [Term] id: CCO:C0002032 name: inhibitory synapse namespace: cellular_component def: "A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell." [GOC:dph, GOC:ef] xref: GO:0060077 is_a: CCO:C0001900 ! synapse [Term] id: CCO:C0002033 name: kinocilium namespace: cellular_component def: "An immotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia." [GOC:dph, PMID:15882574] xref: GO:0060091 is_a: CCO:C0001281 ! nonmotile primary cilium relationship: part_of CCO:C0001447 ! stereocilium bundle [Term] id: CCO:C0002034 name: collagen and cuticulin-based cuticle extracellular matrix namespace: cellular_component def: "A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "collagen and cuticulin-based cuticle extracellular matrix (sensu Nematoda)" RELATED [] synonym: "collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] xref: GO:0060102 is_a: CCO:C0000203 ! proteinaceous extracellular matrix [Term] id: CCO:C0002035 name: collagen and cuticulin-based cuticle extracellular matrix part namespace: cellular_component def: "Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer." [GOC:dph] xref: GO:0060103 is_a: CCO:C0001839 ! extracellular matrix part [Term] id: CCO:C0002036 name: surface coat of collagen and cuticulin-based cuticle extracellular matrix namespace: cellular_component def: "An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "surface coat of collagen and cuticulin-based cuticle extracellular matrix (sensu Nematoda)" RELATED [] synonym: "surface coat of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] xref: GO:0060104 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002034 ! collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002037 name: epicuticle of collagen and cuticulin-based cuticle extracellular matrix namespace: cellular_component def: "A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "epicuticle of collagen and cuticulin-based cuticle extracellular matrix (sensu Nematoda)" RELATED [] synonym: "epicuticle of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] xref: GO:0060105 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002034 ! collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002038 name: cortical layer of collagen and cuticulin-based cuticle extracellular matrix namespace: cellular_component def: "The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "cortical layer of collagen and cuticulin-based cuticle extracellular matrix (sensu Nematoda)" RELATED [] synonym: "cortical layer of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] xref: GO:0060106 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002034 ! collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002039 name: annuli extracellular matrix namespace: cellular_component def: "The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "annulae" RELATED [] synonym: "annular rings" RELATED [] synonym: "annule(s)" RELATED [] synonym: "annulus" RELATED [] xref: GO:0060107 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002038 ! cortical layer of collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002040 name: annular furrow extracellular matrix namespace: cellular_component def: "The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline." [GOC:dph, GOC:kva, ISSN:15518507] xref: GO:0060108 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002038 ! cortical layer of collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002041 name: medial layer of collagen and cuticulin-based cuticle extracellular matrix namespace: cellular_component def: "The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "medial layer struts" RELATED [] xref: GO:0060109 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002034 ! collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002042 name: basal layer of collagen and cuticulin-based cuticle extracellular matrix namespace: cellular_component def: "The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "basal layer of collagen and cuticulin-based cuticle extracellular matrix (sensu Nematoda)" RELATED [] synonym: "basal layer of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] xref: GO:0060110 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002034 ! collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002043 name: alae of collagen and cuticulin-based cuticle extracellular matrix namespace: cellular_component def: "Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively." [GOC:dph, GOC:kva, ISSN:15518507] synonym: "alae of collagen and cuticulin-based cuticle extracellular matrix (sensu Nematoda)" RELATED [] synonym: "alae of collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [] xref: GO:0060111 is_a: CCO:C0002035 ! collagen and cuticulin-based cuticle extracellular matrix part relationship: part_of CCO:C0002034 ! collagen and cuticulin-based cuticle extracellular matrix [Term] id: CCO:C0002044 name: cilium membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a cilium." [GOC:dph, GOC:rh] xref: GO:0060170 is_a: CCO:C0001173 ! cell projection membrane is_a: CCO:C0001860 ! cilium part relationship: location_of CCO:B0043836 ! BBS4_HUMAN [Term] id: CCO:C0002045 name: stereocilium membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a stereocilium." [GOC:dph, GOC:rh] xref: GO:0060171 is_a: CCO:C0001292 ! microvillus membrane relationship: part_of CCO:C0001446 ! stereocilium [Term] id: CCO:C0002047 name: stress granule namespace: cellular_component def: "A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress." [PMID:17601829] xref: GO:0010494 is_a: CCO:C0001019 ! ribonucleoprotein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0011486 ! DDX6_HUMAN-Phosphothreonine36 relationship: location_of CCO:B0063676 ! ATX2_HUMAN-Phosphoserine839 [Term] id: CCO:C0002048 name: exomer complex namespace: cellular_component def: "A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues." [PMID:16498409, PMID:17000877] xref: GO:0034044 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000984 ! trans-Golgi network transport vesicle [Term] id: CCO:C0002049 name: pre-autophagosomal structure membrane namespace: cellular_component def: "A cellular membrane associated with the pre-autophagosomal structure." [GOC:mah, GOC:rph, PMID:16874040, PMID:17382324] synonym: "isolation membrane" RELATED [] synonym: "PAS membrane" EXACT [] xref: GO:0034045 is_a: CCO:C0000766 ! membrane relationship: part_of CCO:C0000077 ! pre-autophagosomal structure [Term] id: CCO:C0002050 name: cell pole namespace: cellular_component def: "Either of two different areas at opposite ends of an axis of a cell." [GOC:dph] xref: GO:0060187 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0002051 name: flagellin-based flagellum filament namespace: cellular_component def: "The long (approximately 20 nm), thin external structure of the flagellum, which acts as a propeller." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar filament" EXACT [] synonym: "flagellar filament (sensu Bacteria)" EXACT [] xref: GO:0009420 is_a: CCO:C0001879 ! flagellin-based flagellum part [Term] id: CCO:C0002052 name: flagellin-based flagellum filament cap namespace: cellular_component def: "The proteinaceous structure at the distal tip of the flagellar filament." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar filament cap" EXACT [] synonym: "flagellar filament cap (sensu Bacteria)" EXACT [] xref: GO:0009421 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0002051 ! flagellin-based flagellum filament [Term] id: CCO:C0002053 name: flagellin-based flagellum hook-filament junction namespace: cellular_component def: "The region of the flagellum where the hook and filament meet." [GOC:mah, GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar hook-filament junction" EXACT [] synonym: "flagellar hook-filament junction (sensu Bacteria)" EXACT [] xref: GO:0009422 is_a: CCO:C0001879 ! flagellin-based flagellum part [Term] id: CCO:C0002054 name: flagellin-based flagellum hook namespace: cellular_component def: "The portion of the flagellum that connects the filament to the basal body." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar hook" EXACT [] synonym: "flagellar hook (sensu Bacteria)" EXACT [] xref: GO:0009424 is_a: CCO:C0001879 ! flagellin-based flagellum part [Term] id: CCO:C0002055 name: flagellin-based flagellum basal body, distal rod namespace: cellular_component def: "The portion of the central rod of the flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes." [GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body, distal rod" EXACT [] synonym: "flagellar basal body, distal rod (sensu Bacteria)" EXACT [] xref: GO:0009426 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0002062 ! flagellin-based flagellum basal body, rod [Term] id: CCO:C0002056 name: flagellin-based flagellum basal body, distal rod, L ring namespace: cellular_component def: "One of the rings of the flagellar basal body; anchors the basal body to the outer membrane." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body, distal rod, L ring" EXACT [] synonym: "flagellar basal body, distal rod, L ring (sensu Bacteria)" EXACT [] xref: GO:0009427 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0002055 ! flagellin-based flagellum basal body, distal rod [Term] id: CCO:C0002057 name: flagellin-based flagellum basal body, distal rod, P ring namespace: cellular_component def: "One of the rings of the flagellar basal body; anchors the basal body to the peptidoglycan layer." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body, distal rod, P ring" RELATED [] synonym: "flagellar basal body, distal rod, P ring (sensu Bacteria)" EXACT [] xref: GO:0009428 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0002055 ! flagellin-based flagellum basal body, distal rod [Term] id: CCO:C0002058 name: flagellin-based flagellum basal body, proximal rod namespace: cellular_component def: "The portion of the central rod of the flagellar basal body that is proximal to the cell membrane; proximal rod connects the distal rod to the flagellar motor." [GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body, proximal rod" EXACT [] synonym: "flagellar basal body, proximal rod (sensu Bacteria)" EXACT [] xref: GO:0009429 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0002062 ! flagellin-based flagellum basal body, rod [Term] id: CCO:C0002059 name: flagellin-based flagellum basal body, MS ring namespace: cellular_component def: "One of the rings of the flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body, mounting plate (sensu Bacteria)" EXACT [] synonym: "flagellar basal body, MS ring" EXACT [] synonym: "flagellar basal body, MS ring (sensu Bacteria)" EXACT [] xref: GO:0009430 xref: GO:0009431 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0000622 ! flagellin-based flagellum basal body [Term] id: CCO:C0002060 name: flagellin-based flagellum basal body, C ring namespace: cellular_component def: "Cytoplasmic ring located at the base of the flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise." [GOC:mtg_sensu, PMID:10572114, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body, C ring" EXACT [] synonym: "flagellar basal body, C ring (sensu Bacteria)" EXACT [] xref: GO:0009433 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0000622 ! flagellin-based flagellum basal body [Term] id: CCO:C0002061 name: plastoglobuli namespace: cellular_component def: "Lipid bodies localized within the chloroplast stroma." [PMID:17259290] xref: GO:0010502 is_a: CCO:C0001853 ! chloroplast part relationship: part_of CCO:C0000681 ! chloroplast stroma [Term] id: CCO:C0002062 name: flagellin-based flagellum basal body, rod namespace: cellular_component def: "The central portion of the flagellar basal body, which spans the periplasm and threads through the rings." [GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192] subset: gosubset_prok synonym: "flagellar basal body, rod" EXACT [] synonym: "flagellar basal body, rod (sensu Bacteria)" EXACT [] xref: GO:0030694 is_a: CCO:C0001879 ! flagellin-based flagellum part relationship: part_of CCO:C0000622 ! flagellin-based flagellum basal body [Term] id: CCO:C0002063 name: NADH dehydrogenase complex namespace: cellular_component def: "An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyses the transfer of a pair of electrons from NADH to a quinone." [GOC:mah] comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (quinone) activity ; GO:0050136'. subset: goslim_pir subset: gosubset_prok synonym: "Complex I" EXACT [] synonym: "NADH dehydrogenase complex (plastoquinone)" NARROW [] synonym: "NADH dehydrogenase complex (plastoquinone) (sensu Cyanobacteria)" NARROW [] synonym: "NADH dehydrogenase complex (quinone) (sensu Bacteria)" NARROW [] synonym: "NADH dehydrogenase complex (ubiquinone) (sensu Bacteria)" NARROW [] synonym: "NADH:plastoquinone reductase complex" NARROW [] synonym: "plastid NADH dehydrogenase complex (plastoquinone)" NARROW [] xref: GO:0030025 xref: GO:0030964 xref: GO:0030966 xref: GO:0031675 xref: GO:0031677 xref: GO:0031678 xref: GO:0045280 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part is_a: CCO:C0001844 ! membrane part [Term] id: CCO:C0002064 name: acidocalcisome lumen namespace: cellular_component def: "The volume enclosed by the membranes of an acidocalcisome." [GOC:mah] xref: GO:0033985 is_a: CCO:C0001749 ! organelle lumen relationship: part_of CCO:C0000919 ! acidocalcisome [Term] id: CCO:C0002065 name: fungal-type spore wall namespace: cellular_component def: "The specialized cell wall of the ascospore (spore), which is the product of meiotic division." [GOC:vw, ISBN:0879693568] synonym: "spore wall (sensu Fungi)" EXACT [] xref: GO:0005619 is_a: CCO:C0001137 ! spore wall [Term] id: CCO:C0002066 name: fungal-type cell wall namespace: cellular_component def: "A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure." [GOC:mcc, GOC:mtg_sensu_feb07, ISBN:3540601864, PMID:11283274, PMID:16927300, PMID:3319422] synonym: "beta-glucan-containing cell wall" RELATED [] synonym: "cell wall (sensu Fungi)" EXACT [] synonym: "chitin- and beta-glucan-containing cell wall" NARROW [] synonym: "chitin-containing cell wall" RELATED [] xref: GO:0009277 is_a: CCO:C0000239 ! cell wall [Term] id: CCO:C0002067 name: TORC1 complex namespace: cellular_component def: "A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates temporal control of cell growth via regulation of translation, transcription, ribosome biogenesis, nutrient transport, and autophagy." [GOC:jh, PMID:15780592] synonym: "nutrient sensitive complex" EXACT [] synonym: "TOR complex 1" EXACT [] synonym: "TORC 1 complex" EXACT [] xref: GO:0031931 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0002068 name: TORC2 complex namespace: cellular_component def: "A protein complex that contains the TOR (target of rapamycin) serine/threonine kinase and mediates spatial control of cell growth via regulation of actin cytoskeleton polarization." [GOC:jh, PMID:15780592] synonym: "TORC 2 complex" EXACT [] xref: GO:0031932 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0070023 ! RICTR_HUMAN-Phosphoserine1388 [Term] id: CCO:C0002069 name: cyanelle stroma namespace: cellular_component def: "The space enclosed by the double membrane of a cyanelle." [GOC:rph] xref: GO:0034060 is_a: CCO:C0000660 ! plastid stroma relationship: part_of CCO:C0000700 ! cyanelle [Term] id: CCO:C0002070 name: Tor2-Mei2-Ste11 complex namespace: cellular_component def: "A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast." [GOC:vw, PMID:17046992] xref: GO:0034064 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0002072 name: Ric1p-Rgp1p complex namespace: cellular_component def: "A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi." [GOC:jh, GOC:mah, PMID:10990452] xref: GO:0034066 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001850 ! Golgi apparatus part [Term] id: CCO:C0002073 name: polyketide synthase complex namespace: cellular_component def: "A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones." [GOC:mah, PMID:12636085] synonym: "PKS" RELATED [] synonym: "PKS complex" EXACT [] xref: GO:0034081 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0002074 name: type II polyketide synthase complex namespace: cellular_component def: "A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction." [GOC:cb, GOC:mah, PMID:12636085] synonym: "type II PKS" EXACT [] synonym: "type II PKS complex" EXACT [] synonym: "type II polyketide synthase" EXACT [] xref: GO:0034082 is_a: CCO:C0002073 ! polyketide synthase complex [Term] id: CCO:C0002075 name: type III polyketide synthase complex namespace: cellular_component def: "A polyketide synthase complex that consists of two identical ketosynthase polypeptides." [GOC:cb, PMID:12636085] synonym: "type III PKS" EXACT [] synonym: "type III PKS complex" EXACT [] synonym: "type III polyketide synthase" EXACT [] xref: GO:0034083 is_a: CCO:C0002073 ! polyketide synthase complex [Term] id: CCO:C0002076 name: Cdc48p-Npl4p-Ufd1p AAA ATPase complex namespace: cellular_component def: "A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins." [PMID:11813000, PMID:16179952] xref: GO:0034098 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0002077 name: luminal surveillance complex namespace: cellular_component def: "A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins." [PMID:16873065] xref: GO:0034099 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000369 ! endoplasmic reticulum lumen [Term] id: CCO:C0002078 name: proteasome complex namespace: cellular_component def: "A large multisubunit complex which catalyzes protein degradation. This complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core." [GOC:rb] subset: goslim_pir synonym: "26S proteasome" NARROW [] synonym: "proteasome complex (sensu Eukaryota)" EXACT [] xref: GO:0000502 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001625 ! PSMD8_HUMAN relationship: location_of CCO:B0001745 ! PSMD2_HUMAN relationship: location_of CCO:B0002066 ! PSMD1_HUMAN relationship: location_of CCO:B0005233 ! PSA1_HUMAN relationship: location_of CCO:B0005586 ! DSS1_HUMAN relationship: location_of CCO:B0006215 ! PSME1_HUMAN relationship: location_of CCO:B0006219 ! PSB10_HUMAN relationship: location_of CCO:B0013617 ! PRS4_HUMAN-Phosphotyrosine439 relationship: location_of CCO:B0013620 ! PSA3_HUMAN-Phosphotyrosine161 relationship: location_of CCO:B0021560 ! PSMD3_HUMAN relationship: location_of CCO:B0022204 ! PSA5_HUMAN relationship: location_of CCO:B0023606 ! PSDE_HUMAN relationship: location_of CCO:B0030804 ! PSB8_HUMAN relationship: location_of CCO:B0030806 ! PSB5_HUMAN relationship: location_of CCO:B0030929 ! PSB3_HUMAN relationship: location_of CCO:B0031007 ! PSB9_HUMAN relationship: location_of CCO:B0032651 ! PSMD6_HUMAN relationship: location_of CCO:B0034007 ! PSB7_HUMAN relationship: location_of CCO:B0035477 ! PSA7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0035478 ! PSB1_HUMAN-Phosphotyrosine150 relationship: location_of CCO:B0035479 ! PSB2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0035483 ! PSD7_HUMAN-Phosphothreonine186 relationship: location_of CCO:B0039597 ! PRS10_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041243 ! PSA2_HUMAN relationship: location_of CCO:B0041244 ! PSA4_HUMAN relationship: location_of CCO:B0041245 ! PSB4_HUMAN relationship: location_of CCO:B0041246 ! PRS7_HUMAN relationship: location_of CCO:B0041247 ! PRS6B_HUMAN relationship: location_of CCO:B0041252 ! PSME3_HUMAN relationship: location_of CCO:B0041253 ! PRS8_HUMAN relationship: location_of CCO:B0041255 ! PSMD5_HUMAN relationship: location_of CCO:B0041315 ! PRS6A_HUMAN-Phosphoserine9 relationship: location_of CCO:B0041328 ! PSD10_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041333 ! PSMD4_HUMAN-Phosphoserine358 [Term] id: CCO:C0002079 name: proteasome regulatory particle namespace: cellular_component def: "A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex." [GOC:mtg_sensu, GOC:proteasome, GOC:rb] synonym: "19S regulatory particle" NARROW [] synonym: "PA700 proteasome activator" NARROW [] synonym: "proteasome regulatory particle (sensu Eukaryota)" EXACT [] xref: GO:0005838 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0001625 ! PSMD8_HUMAN relationship: location_of CCO:B0001745 ! PSMD2_HUMAN relationship: location_of CCO:B0002066 ! PSMD1_HUMAN relationship: location_of CCO:B0035483 ! PSD7_HUMAN-Phosphothreonine186 relationship: location_of CCO:B0039598 ! PSD12_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0041239 ! PSMD9_HUMAN relationship: location_of CCO:B0041328 ! PSD10_HUMAN-N-acetylmethionine1 relationship: part_of CCO:C0002086 ! proteasome accessory complex [Term] id: CCO:C0002080 name: proteasome core complex namespace: cellular_component def: "A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex." [GOC:rb, PMID:10806206] synonym: "20S core complex" NARROW [] synonym: "26S proteasome" NARROW [] synonym: "macropain" EXACT [] synonym: "proteasome core complex (sensu Bacteria)" EXACT [] synonym: "proteasome core complex (sensu Eukaryota)" EXACT [] xref: GO:0000503 xref: GO:0005839 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: location_of CCO:B0005233 ! PSA1_HUMAN relationship: location_of CCO:B0006219 ! PSB10_HUMAN relationship: location_of CCO:B0013620 ! PSA3_HUMAN-Phosphotyrosine161 relationship: location_of CCO:B0022204 ! PSA5_HUMAN relationship: location_of CCO:B0030804 ! PSB8_HUMAN relationship: location_of CCO:B0030806 ! PSB5_HUMAN relationship: location_of CCO:B0030810 ! Q5JNW7_HUMAN relationship: location_of CCO:B0030929 ! PSB3_HUMAN relationship: location_of CCO:B0031007 ! PSB9_HUMAN relationship: location_of CCO:B0031015 ! PSB6_HUMAN relationship: location_of CCO:B0034007 ! PSB7_HUMAN relationship: location_of CCO:B0035477 ! PSA7_HUMAN-N-acetylserine2 relationship: location_of CCO:B0035478 ! PSB1_HUMAN-Phosphotyrosine150 relationship: location_of CCO:B0035479 ! PSB2_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0041243 ! PSA2_HUMAN relationship: location_of CCO:B0041244 ! PSA4_HUMAN relationship: location_of CCO:B0041245 ! PSB4_HUMAN relationship: location_of CCO:B0041251 ! PSA6_HUMAN relationship: location_of CCO:B0069579 ! PSMF1_HUMAN-Phosphoserine252 relationship: part_of CCO:C0002078 ! proteasome complex [Term] id: CCO:C0002081 name: proteasome regulatory particle, base subcomplex namespace: cellular_component def: "The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex." [GOC:mtg_sensu, GOC:proteasome, GOC:rb] synonym: "proteasome regulatory particle, base subcomplex (sensu Eukaryota)" EXACT [] xref: GO:0008540 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0002079 ! proteasome regulatory particle [Term] id: CCO:C0002082 name: proteasome regulatory particle, lid subcomplex namespace: cellular_component def: "The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex." [GOC:rb] synonym: "proteasome regulatory particle, lid subcomplex (sensu Eukaryota)" EXACT [] xref: GO:0008541 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0002079 ! proteasome regulatory particle [Term] id: CCO:C0002083 name: proteasome core complex, alpha-subunit complex namespace: cellular_component def: "The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex." [GOC:jl, GOC:mtg_sensu, GOC:proteasome, GOC:rb, PMID:10854779] synonym: "proteasome core complex, alpha-subunit complex (sensu Eukaryota)" EXACT [] xref: GO:0019773 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0002080 ! proteasome core complex [Term] id: CCO:C0002084 name: proteasome core complex, beta-subunit complex namespace: cellular_component def: "The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex." [GOC:jl, GOC:mtg_sensu, GOC:proteasome, GOC:rb, PMID:10854779] synonym: "proteasome core complex, beta-subunit complex (sensu Eukaryota)" EXACT [] xref: GO:0019774 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part relationship: part_of CCO:C0002080 ! proteasome core complex [Term] id: CCO:C0002085 name: proteasome-activating nucleotidase complex namespace: cellular_component def: "A multisubunit complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner." [GOC:mtg_sensu, GOC:proteasome] synonym: "PAN" EXACT [] xref: GO:0022623 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0002086 ! proteasome accessory complex [Term] id: CCO:C0002086 name: proteasome accessory complex namespace: cellular_component def: "A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex." [GOC:mtg_sensu, GOC:proteasome] xref: GO:0022624 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0002078 ! proteasome complex [Term] id: CCO:C0002087 name: cytosolic large ribosomal subunit namespace: cellular_component def: "The large subunit of the ribosome that is found in the cytosol of the cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:mtg_sensu] synonym: "50S ribosomal subunit" NARROW [] synonym: "60S ribosomal subunit" NARROW [] synonym: "cytosolic large ribosomal subunit (sensu Archaea)" NARROW [] synonym: "cytosolic large ribosomal subunit (sensu Bacteria)" NARROW [] synonym: "cytosolic large ribosomal subunit (sensu Eukaryota)" NARROW [] synonym: "eukaryotic ribosomal LSU" NARROW [] synonym: "prokaryotic large ribosomal subunit" NARROW [] xref: GO:0005842 xref: GO:0009282 xref: GO:0022625 xref: GO:0030498 xref: GO:0030872 is_a: CCO:C0000755 ! large ribosomal subunit is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0005746 ! RL7_HUMAN relationship: location_of CCO:B0005751 ! RL22_HUMAN relationship: location_of CCO:B0005761 ! RL7A_HUMAN relationship: location_of CCO:B0005858 ! RL11_HUMAN relationship: location_of CCO:B0005860 ! RL8_HUMAN relationship: location_of CCO:B0005861 ! RL4_HUMAN relationship: location_of CCO:B0013884 ! RL18A_HUMAN-Phosphotyrosine63 relationship: location_of CCO:B0013886 ! RL18_HUMAN-Phosphoserine130 relationship: location_of CCO:B0013888 ! RL24_HUMAN-Phosphoserine86 relationship: location_of CCO:B0013889 ! RL28_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013896 ! RLA0_HUMAN-Phosphotyrosine24 relationship: location_of CCO:B0013900 ! RLA1_HUMAN-Phosphotyrosine11 relationship: location_of CCO:B0013905 ! RLA2_HUMAN-Phosphoserine102 relationship: location_of CCO:B0029592 ! RL36_HUMAN relationship: location_of CCO:B0036028 ! RL21_HUMAN-Phosphothreonine47 relationship: location_of CCO:B0055717 ! RL6_HUMAN relationship: location_of CCO:B0063083 ! RL3_HUMAN relationship: location_of CCO:B0063091 ! RL35_HUMAN relationship: location_of CCO:B0063356 ! RL27A_HUMAN relationship: location_of CCO:B0063360 ! RL23A_HUMAN relationship: location_of CCO:B0070063 ! RL14_HUMAN-Phosphoserine139 relationship: location_of CCO:B0070079 ! RL26_HUMAN-Phosphothreonine139 relationship: location_of CCO:B0070080 ! RL29_HUMAN-N6-methyllysine5 relationship: location_of CCO:B0070084 ! RL31_HUMAN-Phosphotyrosine108 relationship: location_of CCO:B0070089 ! RL5_HUMAN-Phosphoserine286 relationship: location_of CCO:B0070200 ! RS11_HUMAN-N-acetylalanine2 relationship: part_of CCO:C0002088 ! cytosolic ribosome [Term] id: CCO:C0002088 name: cytosolic ribosome namespace: cellular_component def: "A ribosome that is found in the cytosol of the cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:mtg_sensu] synonym: "70S ribosome" NARROW [] synonym: "80S ribosome" NARROW [] synonym: "cytosolic ribosome (sensu Archaea)" NARROW [] synonym: "cytosolic ribosome (sensu Bacteria)" NARROW [] synonym: "cytosolic ribosome (sensu Eukaryota)" NARROW [] xref: GO:0005830 xref: GO:0009281 xref: GO:0022626 xref: GO:0030871 is_a: CCO:C0000407 ! ribosome is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0033633 ! RL13_HUMAN relationship: location_of CCO:B0059143 ! NUFP1_HUMAN relationship: location_of CCO:B0064911 ! E2AK4_HUMAN-Phosphoserine230 [Term] id: CCO:C0002089 name: cytosolic small ribosomal subunit namespace: cellular_component def: "The small subunit of the ribosome that is found in the cytosol of the cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components." [GOC:mtg_sensu] synonym: "30S ribosomal subunit" NARROW [] synonym: "40S ribosomal subunit" NARROW [] synonym: "cytosolic small ribosomal subunit (sensu Archaea)" NARROW [] synonym: "cytosolic small ribosomal subunit (sensu Bacteria)" NARROW [] synonym: "cytosolic small ribosomal subunit (sensu Eukaryota)" NARROW [] synonym: "eukaryotic ribosomal SSU" NARROW [] synonym: "prokaryotic small ribosomal subunit" NARROW [] xref: GO:0005843 xref: GO:0009283 xref: GO:0022627 xref: GO:0030499 xref: GO:0030873 is_a: CCO:C0000756 ! small ribosomal subunit is_a: CCO:C0001864 ! cytosolic part relationship: location_of CCO:B0001691 ! RS4X_HUMAN relationship: location_of CCO:B0005744 ! RS19_HUMAN relationship: location_of CCO:B0005750 ! RS9_HUMAN relationship: location_of CCO:B0005767 ! RS12_HUMAN relationship: location_of CCO:B0005768 ! RS3A_HUMAN relationship: location_of CCO:B0013932 ! RS10_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0013936 ! RS13_HUMAN-Phosphotyrosine128 relationship: location_of CCO:B0013938 ! RS18_HUMAN-N-acetylserine2 relationship: location_of CCO:B0013939 ! RS20_HUMAN-Phosphothreonine9 relationship: location_of CCO:B0013940 ! RS24_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0013943 ! RS7_HUMAN-N-acetylmethionine1 relationship: location_of CCO:B0030465 ! RS23_HUMAN relationship: location_of CCO:B0033001 ! RS27_HUMAN relationship: location_of CCO:B0034271 ! RS25_HUMAN relationship: location_of CCO:B0035604 ! RS3_HUMAN-Phosphothreonine221 relationship: location_of CCO:B0040516 ! RS14_HUMAN relationship: location_of CCO:B0043825 ! RS15A_HUMAN relationship: location_of CCO:B0063061 ! RS5_HUMAN relationship: location_of CCO:B0063078 ! RS16_HUMAN relationship: location_of CCO:B0063353 ! RS26_HUMAN relationship: location_of CCO:B0063368 ! RS28_HUMAN relationship: location_of CCO:B0063474 ! RS2_HUMAN relationship: location_of CCO:B0070200 ! RS11_HUMAN-N-acetylalanine2 relationship: location_of CCO:B0070214 ! RS6_HUMAN-Phosphoserine78 relationship: location_of CCO:B0070222 ! RS8_HUMAN-Phosphothreonine130 relationship: part_of CCO:C0002088 ! cytosolic ribosome [Term] id: CCO:C0002090 name: chloroplast large ribosomal subunit namespace: cellular_component def: "The large subunit of a ribosome contained within a chloroplast." [GOC:mtg_sensu] synonym: "chloroplast ribosomal large subunit complex" EXACT [] synonym: "chloroplast ribosomal LSU complex" EXACT [] xref: GO:0022628 is_a: CCO:C0000055 ! plastid large ribosomal subunit relationship: part_of CCO:C0001755 ! chloroplast ribosome [Term] id: CCO:C0002091 name: chloroplast small ribosomal subunit namespace: cellular_component def: "The small subunit of a ribosome contained within a chloroplast." [GOC:mtg_sensu] synonym: "chloroplast ribosomal small subunit complex" EXACT [] synonym: "chloroplast ribosomal SSU complex" EXACT [] xref: GO:0022629 is_a: CCO:C0000056 ! plastid small ribosomal subunit relationship: part_of CCO:C0001755 ! chloroplast ribosome [Term] id: CCO:C0002092 name: cytosolic proteasome complex namespace: cellular_component def: "A proteasome complex found in the cytosol of a cell." [GOC:mah, GOC:mtg_sensu, GOC:proteasome] synonym: "cytosolic proteasome complex (sensu Eukaryota)" EXACT [] xref: GO:0031597 is_a: CCO:C0001864 ! cytosolic part is_a: CCO:C0002078 ! proteasome complex [Term] id: CCO:C0002093 name: cytosolic proteasome regulatory particle namespace: cellular_component def: "A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex." [GOC:mah, GOC:mtg_sensu, GOC:proteasome] synonym: "cytosolic proteasome regulatory particle (sensu Eukaryota)" EXACT [] xref: GO:0031600 is_a: CCO:C0001864 ! cytosolic part is_a: CCO:C0002079 ! proteasome regulatory particle relationship: part_of CCO:C0002092 ! cytosolic proteasome complex [Term] id: CCO:C0002094 name: cytosolic proteasome core complex namespace: cellular_component def: "The core complex of a proteasome located in the cytosol of a cell." [GOC:mah, GOC:mtg_sensu, GOC:proteasome] synonym: "cytosolic proteasome core complex (sensu Eukaryota)" EXACT [] xref: GO:0031603 is_a: CCO:C0002080 ! proteasome core complex relationship: part_of CCO:C0002092 ! cytosolic proteasome complex [Term] id: CCO:C0002095 name: cytosolic proteasome core complex, alpha-subunit complex namespace: cellular_component def: "The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex." [GOC:mah, GOC:mtg_sensu, GOC:proteasome] synonym: "cytosolic proteasome core complex, alpha-subunit complex (sensu Eukaryota)" EXACT [] xref: GO:0031606 is_a: CCO:C0001864 ! cytosolic part is_a: CCO:C0002083 ! proteasome core complex, alpha-subunit complex relationship: part_of CCO:C0002094 ! cytosolic proteasome core complex [Term] id: CCO:C0002096 name: cytosolic proteasome core complex, beta-subunit complex namespace: cellular_component def: "The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex." [GOC:mah, GOC:mtg_sensu, GOC:proteasome] synonym: "cytosolic proteasome core complex, beta-subunit complex (sensu Eukaryota)" EXACT [] xref: GO:0031609 is_a: CCO:C0001864 ! cytosolic part is_a: CCO:C0002084 ! proteasome core complex, beta-subunit complex relationship: part_of CCO:C0002094 ! cytosolic proteasome core complex [Term] id: CCO:C0002097 name: cytosolic proteasome regulatory particle, base subcomplex namespace: cellular_component def: "The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell." [GOC:mah, GOC:mtg_sensu, GOC:proteasome] synonym: "cytosolic proteasome regulatory particle, base subcomplex (sensu Eukaryota)" EXACT [] xref: GO:0031612 is_a: CCO:C0001864 ! cytosolic part is_a: CCO:C0002081 ! proteasome regulatory particle, base subcomplex relationship: part_of CCO:C0002093 ! cytosolic proteasome regulatory particle [Term] id: CCO:C0002098 name: cytosolic proteasome regulatory particle, lid subcomplex namespace: cellular_component def: "The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex." [GOC:mah, GOC:mtg_sensu, GOC:proteasome] synonym: "cytosolic proteasome regulatory particle, lid subcomplex (sensu Eukaryota)" EXACT [] xref: GO:0031615 is_a: CCO:C0001864 ! cytosolic part is_a: CCO:C0002082 ! proteasome regulatory particle, lid subcomplex relationship: part_of CCO:C0002093 ! cytosolic proteasome regulatory particle [Term] id: CCO:C0002099 name: enhanceosome namespace: cellular_component def: "A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation." [PMID:11250145, PMID:17574024] xref: GO:0034206 is_a: CCO:C0001494 ! protein-DNA complex [Term] id: CCO:C0002100 name: ER ubiquitin ligase complex namespace: cellular_component def: "A ubiquitin ligase complex found in the ER." [GOC:elh] xref: GO:0000835 is_a: CCO:C0000028 ! cytoplasmic ubiquitin ligase complex relationship: part_of CCO:C0000370 ! endoplasmic reticulum membrane [Term] id: CCO:C0002101 name: Hrd1p ubiquitin ligase complex namespace: cellular_component def: "A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p." [GOC:elh, PMID:16873066] xref: GO:0000836 is_a: CCO:C0002100 ! ER ubiquitin ligase complex [Term] id: CCO:C0002102 name: Doa10p ubiquitin ligase complex namespace: cellular_component def: "A multiprotein complex that recognizes and ubiquitinates membranes proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p." [GOC:elh, PMID:16873066] synonym: "Ssm4p ubiquitin ligase complex" EXACT [] xref: GO:0000837 is_a: CCO:C0002100 ! ER ubiquitin ligase complex [Term] id: CCO:C0002103 name: Hrd1p ubiquitin ligase ERAD-M complex namespace: cellular_component def: "A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p." [GOC:elh, PMID:16873066] xref: GO:0000838 is_a: CCO:C0002101 ! Hrd1p ubiquitin ligase complex [Term] id: CCO:C0002104 name: Hrd1p ubiquitin ligase ERAD-L complex namespace: cellular_component def: "A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p." [GOC:elh, PMID:16873065, PMID:16873066] xref: GO:0000839 is_a: CCO:C0002101 ! Hrd1p ubiquitin ligase complex [Term] id: CCO:C0002105 name: cyclic-nucleotide phosphodiesterase complex namespace: cellular_component def: "An enzyme complex that catalyzes the hydrolysis of bonds in a cyclic nucleotide." [EC:3.1.4.-] synonym: "photoreceptor cyclic-nucleotide phosphodiesterase complex" NARROW [] xref: GO:0005966 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0002106 name: mitochondrial DNA-directed RNA polymerase complex namespace: cellular_component def: "A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form." [GOC:krc, GOC:mah, PMID:7929382] synonym: "mitochondrial RNA polymerase complex" BROAD [] synonym: "mitochondrial RNA polymerase holoenzyme complex" EXACT [] xref: GO:0034245 is_a: CCO:C0000085 ! DNA-directed RNA polymerase complex is_a: CCO:C0001848 ! mitochondrial part [Term] id: CCO:C0002107 name: clathrin sculpted vesicle namespace: cellular_component def: "A clathrin sculpted lipid bilayer membrane enclosed vesicle after clathrin release." [GOC:dph] xref: GO:0060198 is_a: CCO:C0000981 ! clathrin-coated vesicle [Term] id: CCO:C0002108 name: clathrin sculpted glutamate transport vesicle namespace: cellular_component def: "A clathrin sculpted lipid bilayer membrane enclosed vesicle after clathrin release and containing glutamate." [GOC:dph] xref: GO:0060199 is_a: CCO:C0000978 ! transport vesicle is_a: CCO:C0002107 ! clathrin sculpted vesicle [Term] id: CCO:C0002109 name: clathrin sculpted acetylcholine transport vesicle namespace: cellular_component def: "A clathrin sculpted lipid bilayer membrane enclosed vesicle after clathrin release and containing acetylcholine." [GOC:dph] xref: GO:0060200 is_a: CCO:C0000978 ! transport vesicle is_a: CCO:C0002107 ! clathrin sculpted vesicle [Term] id: CCO:C0002110 name: clathrin sculpted acetylcholine transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a clathrin sculpted acetylcholine transport vesicle." [GOC:dph] xref: GO:0060201 is_a: CCO:C0001023 ! transport vesicle membrane is_a: CCO:C0001029 ! clathrin coated vesicle membrane relationship: part_of CCO:C0002109 ! clathrin sculpted acetylcholine transport vesicle [Term] id: CCO:C0002111 name: clathrin sculpted acetylcholine transport vesicle lumen namespace: cellular_component def: "The volume enclosed by the membrane of the clathrin sculpted acetylcholine transport vesicle." [GOC:dph] xref: GO:0060202 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0002109 ! clathrin sculpted acetylcholine transport vesicle [Term] id: CCO:C0002112 name: clathrin sculpted glutamate transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a clathrin sculpted glutamate transport vesicle." [GOC:dph] xref: GO:0060203 is_a: CCO:C0001023 ! transport vesicle membrane is_a: CCO:C0001029 ! clathrin coated vesicle membrane relationship: part_of CCO:C0002108 ! clathrin sculpted glutamate transport vesicle [Term] id: CCO:C0002113 name: clathrin sculpted glutamate transport vesicle lumen namespace: cellular_component def: "The volume enclosed by the membrane of the clathrin sculpted glutamate transport vesicle." [GOC:dph] xref: GO:0060204 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0002108 ! clathrin sculpted glutamate transport vesicle [Term] id: CCO:C0002115 name: 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex namespace: cellular_component def: "A heterodimeric protein complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic Class IA phosphoinositide 3-kinase (PI3K) subunit of 110-120 kDa and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways." [PMID:9255069, PMID:9759495] synonym: "1-phosphatidylinositol-4-phosphate kinase, class IA complex" EXACT [] synonym: "class IA PI3K complex" EXACT [] synonym: "phosphoinositide 3-kinase complex, class IA" EXACT [] xref: GO:0005943 xref: GO:0035030 is_a: CCO:C0000492 ! phosphoinositide 3-kinase complex relationship: location_of CCO:B0069034 ! P85A_HUMAN-Phosphotyrosine467 [Term] id: CCO:C0002116 name: 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex namespace: cellular_component def: "A heterodimeric protein complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic Class IB phosphoinositide 3-kinase (PI3K) subunit of 110-120 kDa and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks." [PMID:9255069, PMID:9759495] synonym: "1-phosphatidylinositol-4-phosphate kinase, class IB complex" RELATED [] synonym: "class IB PI3K complex" EXACT [] synonym: "phosphoinositide 3-kinase complex, class IB" EXACT [] xref: GO:0005944 xref: GO:0035031 is_a: CCO:C0000492 ! phosphoinositide 3-kinase complex [Term] id: CCO:C0002117 name: serine-pyruvate aminotransferase complex namespace: cellular_component def: "An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate." [EC:2.6.1.51] synonym: "serine-pyruvate aminotransferase, type 1 complex" NARROW [] synonym: "serine-pyruvate aminotransferase, type 2B complex" NARROW [] xref: GO:0005969 xref: GO:0005970 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part relationship: location_of CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:C0002118 name: CVT complex namespace: cellular_component def: "A protein complex that is involved in the CVT pathway. In budding yeast, the CVT complex consists of multimers of preApe1p." [GOC:rb, PMID:15659643] xref: GO:0034270 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0002119 name: phosphatidylinositol 3-kinase complex I namespace: cellular_component def: "A protein complex that posseses phosphatidylinositol 3-kinase activity and is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Atg14p and Vps15p." [GOC:rb, PMID:11157979, PMID:16421251] comment: Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'. synonym: "PtdIns-3-kinase complex I" EXACT [] xref: GO:0034271 is_a: CCO:C0000492 ! phosphoinositide 3-kinase complex [Term] id: CCO:C0002120 name: phosphatidylinositol 3-kinase complex II namespace: cellular_component def: "A protein complex that posseses phosphatidylinositol 3-kinase activity and is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, VPS38 and Vps15p." [GOC:rb, PMID:11157979, PMID:16421251] comment: Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'. synonym: "PtdIns-3-kinase complex II" EXACT [] xref: GO:0034272 is_a: CCO:C0000492 ! phosphoinositide 3-kinase complex [Term] id: CCO:C0002121 name: Atg1p signaling complex namespace: cellular_component def: "A protein complex that contains a protein kinase and is required for the autophagosome formation. In budding yeast this complex consists of the kinase Atg1p, Atg13p and Atg17p." [GOC:rb, PMID:15743910] synonym: "Atg1p signalling complex" EXACT [] xref: GO:0034273 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0002122 name: Atg12-Atg5-Atg16 complex namespace: cellular_component def: "A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p." [GOC:rb, PMID:17986448] xref: GO:0034274 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001863 ! cytoplasmic part [Term] id: CCO:C0002123 name: membrane raft namespace: cellular_component def: "Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions." [PMID:16645198] synonym: "GEM domain" RELATED [] synonym: "glycolipid-enriched membrane domain" RELATED [] synonym: "lipid raft" EXACT [] xref: GO:0045121 is_a: CCO:C0001844 ! membrane part relationship: location_of CCO:B0001406 ! ADCY3_HUMAN relationship: location_of CCO:B0001458 ! BCL10_HUMAN relationship: location_of CCO:B0001490 ! LCK_HUMAN relationship: location_of CCO:B0005605 ! CFTR_HUMAN relationship: location_of CCO:B0010930 ! CAV1_HUMAN-Phosphotyrosine6 relationship: location_of CCO:B0010937 ! CAV2_HUMAN-Phosphotyrosine27 relationship: location_of CCO:B0012433 ! JAK2_HUMAN-Phosphotyrosine1007 relationship: location_of CCO:B0023551 ! RAB5A_HUMAN relationship: location_of CCO:B0031337 ! LYN_HUMAN-Phosphotyrosine194 relationship: location_of CCO:B0034497 ! ABCA1_HUMAN-Phosphoserine1141 relationship: location_of CCO:B0043436 ! PRIO_HUMAN relationship: location_of CCO:B0048252 ! EFNB1_HUMAN-Phosphotyrosine317 relationship: location_of CCO:B0049794 ! PPT1_HUMAN relationship: location_of CCO:B0054889 ! THY1_HUMAN relationship: location_of CCO:B0054928 ! CD14_HUMAN relationship: location_of CCO:B0054945 ! WNT2_HUMAN relationship: location_of CCO:B0055131 ! MAL_HUMAN relationship: location_of CCO:B0055177 ! CD24_HUMAN relationship: location_of CCO:B0055310 ! ACHA7_HUMAN relationship: location_of CCO:B0055468 ! P2RX1_HUMAN relationship: location_of CCO:B0055545 ! CAV3_HUMAN relationship: location_of CCO:B0055893 ! CLN3_HUMAN relationship: location_of CCO:B0056066 ! SHH_HUMAN relationship: location_of CCO:B0057894 ! STML3_HUMAN relationship: location_of CCO:B0058002 ! ITLN1_HUMAN relationship: location_of CCO:B0058004 ! ASZ1_HUMAN relationship: location_of CCO:B0058050 ! CTTB2_HUMAN relationship: location_of CCO:B0058105 ! GHSR_HUMAN relationship: location_of CCO:B0058559 ! CAR11_HUMAN relationship: location_of CCO:B0058578 ! ACE2_HUMAN relationship: location_of CCO:B0062929 ! MALL_HUMAN relationship: location_of CCO:B0063454 ! CD48_HUMAN relationship: location_of CCO:B0064015 ! BTK_HUMAN-Phosphotyrosine344 relationship: location_of CCO:B0064174 ! CD79A_HUMAN-Phosphotyrosine210 relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: location_of CCO:B0066215 ! FLOT2_HUMAN-Phosphotyrosine192 relationship: location_of CCO:B0066332 ! FYV1_HUMAN-Phosphotyrosine1772 relationship: location_of CCO:B0067581 ! LAT_HUMAN-Phosphoserine84 relationship: location_of CCO:B0067594 ! LAX1_HUMAN-Phosphotyrosine373 relationship: location_of CCO:B0068876 ! NTAL_HUMAN-Phosphotyrosine233 relationship: location_of CCO:B0069056 ! PAG1_HUMAN-Phosphotyrosine227 relationship: location_of CCO:B0070868 ! SRBS1_HUMAN-Phosphothreonine862 relationship: location_of CCO:B0070985 ! STX12_HUMAN-Phosphoserine142 [Term] id: CCO:C0002124 name: cytoplasmic membrane-bounded vesicle namespace: cellular_component def: "A membrane-bounded vesicle found in the cytoplasm of the cell." [GOC:ai, GOC:mah] subset: goslim_candida subset: goslim_generic subset: goslim_yeast subset: gosubset_prok synonym: "cytoplasmic membrane bounded vesicle" EXACT [] synonym: "cytoplasmic membrane-enclosed vesicle" EXACT [] xref: GO:0016023 is_a: CCO:C0001235 ! cytoplasmic vesicle is_a: CCO:C0002125 ! membrane-bounded vesicle is_a: CCO:C0002129 ! intracellular membrane-bounded organelle relationship: location_of CCO:B0005950 ! BECN1_HUMAN relationship: location_of CCO:B0013068 ! MYO6_HUMAN-Phosphothreonine405 relationship: location_of CCO:B0019513 ! TAOK2_HUMAN relationship: location_of CCO:B0034592 ! BPA1_HUMAN-Phosphothreonine224 relationship: location_of CCO:B0039613 ! RB11B_HUMAN-N-acetylglycine2 relationship: location_of CCO:B0054391 ! GIPC1_HUMAN relationship: location_of CCO:B0055486 ! GDIR2_HUMAN relationship: location_of CCO:B0056176 ! DGKD_HUMAN relationship: location_of CCO:B0058421 ! SORT_HUMAN relationship: location_of CCO:B0058457 ! GDIR3_HUMAN relationship: location_of CCO:B0062929 ! MALL_HUMAN relationship: location_of CCO:B0062978 ! HPS1_HUMAN relationship: location_of CCO:B0065266 ! ABCA2_HUMAN-Phosphoserine1331 relationship: location_of CCO:B0069088 ! PALM_HUMAN-Phosphothreonine158 relationship: location_of CCO:B0071374 ! TFR1_HUMAN-Phosphotyrosine20 [Term] id: CCO:C0002125 name: membrane-bounded vesicle namespace: cellular_component def: "Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer." [GOC:mah] subset: gosubset_prok synonym: "membrane-enclosed vesicle" EXACT [] xref: GO:0031988 is_a: CCO:C0001374 ! vesicle [Term] id: CCO:C0002126 name: host intracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] subset: gosubset_prok synonym: "host intracellular membrane-enclosed organelle" EXACT [] xref: GO:0033648 is_a: CCO:C0001592 ! host intracellular organelle [Term] id: CCO:C0002127 name: membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] subset: gosubset_prok synonym: "membrane-enclosed organelle" EXACT [] xref: GO:0043227 is_a: CCO:C0001742 ! organelle [Term] id: CCO:C0002128 name: non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: gosubset_prok synonym: "non-membrane-enclosed organelle" EXACT [] xref: GO:0043228 is_a: CCO:C0001742 ! organelle [Term] id: CCO:C0002129 name: intracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir subset: gosubset_prok synonym: "intracellular membrane-enclosed organelle" EXACT [] xref: GO:0043231 is_a: CCO:C0001745 ! intracellular organelle is_a: CCO:C0002127 ! membrane-bounded organelle relationship: location_of CCO:B0022913 ! GLRA1_HUMAN relationship: location_of CCO:B0043213 ! BNIP2_HUMAN-Phosphoserine114 relationship: location_of CCO:B0055862 ! SEC20_HUMAN [Term] id: CCO:C0002130 name: intracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: goslim_pir subset: gosubset_prok synonym: "intracellular non-membrane-enclosed organelle" EXACT [] xref: GO:0043232 is_a: CCO:C0001745 ! intracellular organelle is_a: CCO:C0002128 ! non-membrane-bounded organelle [Term] id: CCO:C0002131 name: extracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:jl] subset: gosubset_prok synonym: "extracellular non-membrane-enclosed organelle" EXACT [] xref: GO:0043264 is_a: CCO:C0001746 ! extracellular organelle is_a: CCO:C0002128 ! non-membrane-bounded organelle [Term] id: CCO:C0002132 name: cytoplasmic membrane-bounded vesicle lumen namespace: cellular_component def: "The volume enclosed by the membrane of a cytoplasmic membrane-bounded vesicle." [GOC:dph] synonym: "cytoplasmic membrane-enclosed vesicle lumen" EXACT [] xref: GO:0060205 is_a: CCO:C0001375 ! vesicle lumen is_a: CCO:C0001852 ! cytoplasmic vesicle part relationship: part_of CCO:C0002124 ! cytoplasmic membrane-bounded vesicle [Term] id: CCO:C0002133 name: extracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete] synonym: "extracellular membrane-enclosed organelle" EXACT [] xref: GO:0065010 is_a: CCO:C0001746 ! extracellular organelle is_a: CCO:C0002127 ! membrane-bounded organelle [Term] id: CCO:C0002134 name: intracellular immature spore namespace: cellular_component def: "A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants." [GOC:jl, ISBN:0395825172] subset: gosubset_prok synonym: "forespore" RELATED [] xref: GO:0042763 is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0002135 name: ascospore-type prospore namespace: cellular_component def: "An immature spore, of the type observed in ascopore-forming fungi, undergoing development; usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s)." [GOC:go_curators] subset: gosubset_prok synonym: "forespore (sensu Fungi)" BROAD [] xref: GO:0042764 is_a: CCO:C0002134 ! intracellular immature spore [Term] id: CCO:C0002136 name: cell-substrate junction namespace: cellular_component def: "A specialized region of connection between a cell and the extracellular matrix." [GOC:hb] synonym: "cell-matrix junction" EXACT [] xref: GO:0030055 is_a: CCO:C0000936 ! cell junction relationship: location_of CCO:B0043497 ! VINC_HUMAN-Phosphothreonine324 relationship: part_of CCO:C0000780 ! basolateral plasma membrane [Term] id: CCO:C0002137 name: photosynthetic membrane namespace: cellular_component def: "A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place." [GOC:ds, GOC:mah] subset: gosubset_prok xref: GO:0034357 is_a: CCO:C0000766 ! membrane [Term] id: CCO:C0002138 name: plasma lipoprotein particle namespace: cellular_component def: "A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph." [GOC:expert_pt, GOC:rl] xref: GO:0034358 is_a: CCO:C0001495 ! protein-lipid complex relationship: part_of CCO:C0000237 ! extracellular space [Term] id: CCO:C0002139 name: mature chylomicron namespace: cellular_component def: "A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph." [GOC:expert_pt, GOC:mah, GOC:rl] xref: GO:0034359 is_a: CCO:C0001672 ! chylomicron [Term] id: CCO:C0002140 name: chylomicron remnant namespace: cellular_component def: "A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver." [GOC:expert_pt, GOC:mah, GOC:rl] xref: GO:0034360 is_a: CCO:C0001672 ! chylomicron [Term] id: CCO:C0002141 name: very-low-density lipoprotein particle namespace: cellular_component def: "A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver." [GOC:expert_pt, GOC:mah, GOC:rl] synonym: "very-low-density lipoprotein complex" EXACT [] synonym: "VLDL complex" EXACT [] synonym: "VLDL particle" EXACT [] xref: GO:0034361 is_a: CCO:C0002147 ! triglyceride-rich lipoprotein particle relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054863 ! APOA2_HUMAN relationship: location_of CCO:B0054864 ! APOC3_HUMAN relationship: location_of CCO:B0056927 ! APOA5_HUMAN relationship: location_of CCO:B0058480 ! SELS_HUMAN [Term] id: CCO:C0002142 name: low-density lipoprotein particle namespace: cellular_component def: "A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triacylglycerol and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver." [GOC:expert_pt, GOC:mah, GOC:rl] synonym: "LDL complex" EXACT [] synonym: "LDL particle" EXACT [] synonym: "low-density lipoprotein complex" EXACT [] xref: GO:0034362 is_a: CCO:C0002138 ! plasma lipoprotein particle relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054863 ! APOA2_HUMAN relationship: location_of CCO:B0056927 ! APOA5_HUMAN relationship: location_of CCO:B0058480 ! SELS_HUMAN [Term] id: CCO:C0002143 name: intermediate-density lipoprotein particle namespace: cellular_component def: "A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL)." [GOC:expert_pt, GOC:mah, GOC:rl] synonym: "IDL complex" EXACT [] synonym: "IDL particle" EXACT [] synonym: "intermediate-density lipoprotein complex" EXACT [] xref: GO:0034363 is_a: CCO:C0002147 ! triglyceride-rich lipoprotein particle relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054864 ! APOC3_HUMAN [Term] id: CCO:C0002144 name: high-density lipoprotein particle namespace: cellular_component def: "A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process." [GOC:expert_pt, GOC:mah, GOC:pd, GOC:rl] synonym: "HDL complex" EXACT [] synonym: "HDL particle" EXACT [] synonym: "HDL2" RELATED [] synonym: "HDL3" RELATED [] synonym: "high-density lipoprotein class complex" EXACT [] xref: GO:0034364 is_a: CCO:C0002138 ! plasma lipoprotein particle relationship: location_of CCO:B0028600 ! APOA1_HUMAN relationship: location_of CCO:B0054862 ! APOE_HUMAN relationship: location_of CCO:B0054863 ! APOA2_HUMAN relationship: location_of CCO:B0056927 ! APOA5_HUMAN relationship: location_of CCO:B0062887 ! CETP_HUMAN [Term] id: CCO:C0002145 name: discoidal high-density lipoprotein particle namespace: cellular_component def: "A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase)." [GOC:expert_pt, GOC:mah, GOC:rl] synonym: "discoidal HDL" EXACT [] synonym: "nascent HDL" EXACT [] synonym: "nascent high-density lipoprotein particle" EXACT [] xref: GO:0034365 is_a: CCO:C0002144 ! high-density lipoprotein particle [Term] id: CCO:C0002146 name: spherical high-density lipoprotein particle namespace: cellular_component def: "A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT)." [GOC:expert_pt, GOC:mah, GOC:rl] synonym: "mature HDL" EXACT [] synonym: "mature high-density lipoprotein particle" EXACT [] synonym: "spherical HDL" EXACT [] xref: GO:0034366 is_a: CCO:C0002144 ! high-density lipoprotein particle relationship: location_of CCO:B0054864 ! APOC3_HUMAN [Term] id: CCO:C0002147 name: triglyceride-rich lipoprotein particle namespace: cellular_component def: "A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoproteinparticles transport lipids, which are non-covalently associated with the particles, in the blood." [GOC:mah, GOC:rl] xref: GO:0034385 is_a: CCO:C0002138 ! plasma lipoprotein particle [Term] id: CCO:C0002148 name: Pwp2p-containing subcomplex of 90S preribosome namespace: cellular_component def: "A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p." [GOC:krc, PMID:15231838] comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. synonym: "25-30 S subcomplex of 90S preribosome" EXACT [] synonym: "UTP-B complex" EXACT [] xref: GO:0034388 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001871 ! nucleolar part relationship: part_of CCO:C0001045 ! 90S preribosome [Term] id: CCO:C0002149 name: nuclear periphery namespace: cellular_component def: "The region of the nucleus adjacent to the nuclear envelope." [GOC:krc] xref: GO:0034399 is_a: CCO:C0001847 ! nuclear part [Term] id: CCO:C0002150 name: gerontoplast namespace: cellular_component def: "A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence." [PMID:12654863, PMID:16151876] xref: GO:0034400 is_a: CCO:C0000664 ! plastid [Term] id: CCO:C0002151 name: fungal-type vacuole namespace: cellular_component def: "A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure." [GOC:mah, GOC:mtg_sensu, ISBN:0879693649] synonym: "vacuole (sensu Fungi)" EXACT [] synonym: "vacuole, cell cycle-correlated morphology" EXACT [] xref: GO:0000324 is_a: CCO:C0000060 ! storage vacuole is_a: CCO:C0000061 ! lytic vacuole [Term] id: CCO:C0002152 name: plant-type vacuole namespace: cellular_component def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase." [GOC:mtg_sensu, ISBN:0815316208] synonym: "vacuole (sensu Magnoliophyta)" RELATED [] synonym: "vacuole, cell cycle-independent morphology" EXACT [] xref: GO:0000325 is_a: CCO:C0000355 ! vacuole [Term] id: CCO:C0002153 name: fungal-type vacuole lumen namespace: cellular_component def: "The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase." [GOC:krc, GOC:mtg_sensu] synonym: "lumen of vacuole with cell cycle-correlated morphology" EXACT [] synonym: "vacuolar lumen (sensu Fungi)" RELATED [] xref: GO:0000328 is_a: CCO:C0000357 ! vacuolar lumen relationship: part_of CCO:C0002151 ! fungal-type vacuole [Term] id: CCO:C0002154 name: fungal-type vacuole membrane namespace: cellular_component def: "The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell." [GOC:krc, GOC:mtg_sensu] synonym: "fungal-type vacuolar membrane" RELATED [] synonym: "membrane of vacuole with cell cycle-correlated morphology" EXACT [] synonym: "vacuolar membrane (sensu Fungi)" EXACT [] xref: GO:0000329 is_a: CCO:C0000356 ! vacuolar membrane relationship: part_of CCO:C0002151 ! fungal-type vacuole [Term] id: CCO:C0002155 name: plant-type vacuole lumen namespace: cellular_component def: "The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase." [GOC:krc, GOC:mtg_sensu] synonym: "lumen of vacuole with cell cycle-independent morphology" EXACT [] synonym: "vacuolar lumen (sensu Magnoliophyta)" EXACT [] xref: GO:0000330 is_a: CCO:C0000357 ! vacuolar lumen relationship: part_of CCO:C0002152 ! plant-type vacuole [Term] id: CCO:C0002156 name: Gram-positive-bacterium-type cell wall namespace: cellular_component def: "A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. As in but not restricted to the Gram-positive bacteria." [GOC:mlg, ISBN:0815108893, PMID:0051406910] subset: gosubset_prok synonym: "20-80nm peptidoglycan-based cell wall" EXACT [] synonym: "cell wall (sensu Firmicutes)" EXACT [] synonym: "cell wall (sensu Gram-positive Bacteria)" EXACT [] synonym: "cell wall of Gram-positive Bacteria" EXACT [] xref: GO:0009275 is_a: CCO:C0000553 ! peptidoglycan-based cell wall [Term] id: CCO:C0002157 name: Gram-negative-bacterium-type cell wall namespace: cellular_component def: "The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain. As in but not restricted to the Gram-negative bacteria." [GOC:mlg, ISBN:0815108893] subset: gosubset_prok synonym: "1-2nm peptidoglycan-based cell wall" EXACT [] synonym: "cell wall (sensu Gram-negative Bacteria)" EXACT [] synonym: "cell wall (sensu Proteobacteria)" EXACT [] synonym: "cell wall inner membrane" EXACT [] xref: GO:0009276 is_a: CCO:C0000553 ! peptidoglycan-based cell wall is_a: CCO:C0001880 ! external encapsulating structure part relationship: part_of CCO:C0001000 ! cell envelope [Term] id: CCO:C0002158 name: plant-type cell wall namespace: cellular_component def: "A more or less rigid stucture enclosing the protoplast of a cell and composed of cellulose and pectin and other organic and inorganic substances. As in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398)." [ISBN:0471245208] synonym: "cell wall (sensu Magnoliophyta)" EXACT [] synonym: "cellulose and pectin-containing cell wall" EXACT [] xref: GO:0009505 is_a: CCO:C0000239 ! cell wall [Term] id: CCO:C0002159 name: plant-type vacuole membrane namespace: cellular_component def: "The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell." [GOC:mtg_sensu, ISBN:0471245208] synonym: "membrane of vacuole with cell cycle-independent morphology" EXACT [] synonym: "tonoplast" EXACT [] synonym: "vacuolar membrane (sensu Magnoliophyta)" EXACT [] xref: GO:0009705 is_a: CCO:C0000356 ! vacuolar membrane relationship: part_of CCO:C0002152 ! plant-type vacuole [Term] id: CCO:C0002160 name: cell envelope Sec complex namespace: cellular_component def: "A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC." [GOC:mtg_sensu, PMID:15223057] subset: gosubset_prok synonym: "plasma membrane Sec complex" RELATED [] synonym: "Sec complex (sensu Bacteria)" EXACT [] xref: GO:0031522 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001882 ! cell part [Term] id: CCO:C0002161 name: aleurone grain lumen namespace: cellular_component def: "The volume enclosed by the membrane of an aleurone grain." [GOC:rph] xref: GO:0034422 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0001516 ! aleurone grain [Term] id: CCO:C0002162 name: autophagic vacuole lumen namespace: cellular_component def: "The volume enclosed within the autophagic vacuole membrane." [GOC:rph] comment: Note that this term should be used for annotating gene products with caution: it should be used only to annotate gene products demonstrated to reside and function normally in the autophagic vacuole lumen, not for molecules that are temporarily found in the lumen prior to degradation. xref: GO:0034423 is_a: CCO:C0000357 ! vacuolar lumen relationship: part_of CCO:C0000358 ! autophagic vacuole [Term] id: CCO:C0002163 name: Vps55/Vps68 complex namespace: cellular_component def: "A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins." [PMID:18216282] xref: GO:0034424 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000713 ! endosome membrane [Term] id: CCO:C0002164 name: etioplast envelope namespace: cellular_component def: "The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space." [GOC:mah] xref: GO:0034425 is_a: CCO:C0000654 ! plastid envelope relationship: part_of CCO:C0000642 ! etioplast [Term] id: CCO:C0002165 name: etioplast membrane namespace: cellular_component def: "Either of the lipid bilayers that surround a etioplast and form the etioplast envelope." [GOC:rph] xref: GO:0034426 is_a: CCO:C0001634 ! plastid membrane relationship: part_of CCO:C0002164 ! etioplast envelope [Term] id: CCO:C0002166 name: monolayer-surrounded lipid storage body outer lipid monolayer namespace: cellular_component def: "The single layer of phopholipids surrounding a lipid storage body." [GOC:rph] synonym: "lipid droplet outer lipid monolayer" RELATED [] synonym: "lipid storage body surface lipid monolayer" EXACT [] synonym: "oil body outer lipid monolayer" EXACT [] synonym: "oleosome outer lipid monolayer" EXACT [] synonym: "spherosome outer lipid monolayer" EXACT [] xref: GO:0034430 is_a: CCO:C0002199 ! organelle-enclosing lipid monolayer relationship: location_of CCO:B0002253 ! STA13_HUMAN relationship: location_of CCO:B0063516 ! M6PBP_HUMAN relationship: part_of CCO:C0000739 ! monolayer-surrounded lipid storage body [Term] id: CCO:C0002167 name: striated muscle dense body namespace: cellular_component def: "A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere." [GOC:kmva, PMID:17492481] xref: GO:0055120 is_a: CCO:C0001868 ! contractile fiber part [Term] id: CCO:C0002168 name: chromosome, centromeric region namespace: cellular_component def: "The region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome." [GOC:elh, GOC:kva] comment: Note that this term can be used in place of the obsoleted cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. synonym: "centromere" RELATED [] synonym: "chromosome, centric region" EXACT [] synonym: "chromosome, pericentric region" RELATED [] xref: GO:0000775 is_a: CCO:C0001846 ! chromosomal part relationship: location_of CCO:B0001391 ! SUV91_HUMAN relationship: location_of CCO:B0001847 ! SGOL1_HUMAN relationship: location_of CCO:B0002115 ! NUF2_HUMAN relationship: location_of CCO:B0002122 ! MIS12_HUMAN relationship: location_of CCO:B0002161 ! HELLS_HUMAN relationship: location_of CCO:B0005431 ! CENPB_HUMAN relationship: location_of CCO:B0005682 ! CENPH_HUMAN relationship: location_of CCO:B0006198 ! CENPR_HUMAN relationship: location_of CCO:B0010723 ! AURKB_HUMAN-Phosphotyrosine12 relationship: location_of CCO:B0010799 ! BIRC5_HUMAN-Phosphothreonine34 relationship: location_of CCO:B0010825 ! BOREA_HUMAN-Phosphoserine219 relationship: location_of CCO:B0010965 ! CBX1_HUMAN-Phosphoserine89 relationship: location_of CCO:B0010970 ! CBX5_HUMAN-Phosphoserine13 relationship: location_of CCO:B0011143 ! CENPC_HUMAN-Phosphoserine520 relationship: location_of CCO:B0011148 ! CENPE_HUMAN-Phosphothreonine544 relationship: location_of CCO:B0011163 ! CENPF_HUMAN-Phosphoserine1324 relationship: location_of CCO:B0012399 ! INCE_HUMAN-Phosphoserine296 relationship: location_of CCO:B0013638 ! PSN1_HUMAN-Phosphoserine346 relationship: location_of CCO:B0013810 ! RCC2_HUMAN-Phosphothreonine20 relationship: location_of CCO:B0014044 ! SGOL2_HUMAN-Phosphothreonine845 relationship: location_of CCO:B0014074 ! SMC1B_HUMAN-Phosphoserine882 relationship: location_of CCO:B0014764 ! ZW10_HUMAN-Phosphothreonine438 relationship: location_of CCO:B0031347 ! NDC80_HUMAN-Phosphoserine165 relationship: location_of CCO:B0039136 ! TIGD3_HUMAN relationship: location_of CCO:B0041237 ! B1AQT3_HUMAN relationship: location_of CCO:B0041238 ! B1AQT4_HUMAN relationship: location_of CCO:B0041256 ! ERC6L_HUMAN relationship: location_of CCO:B0055926 ! Q13537_HUMAN relationship: location_of CCO:B0056185 ! TIGD6_HUMAN relationship: location_of CCO:B0056238 ! Q32MC2_HUMAN relationship: location_of CCO:B0056335 ! TIGD2_HUMAN relationship: location_of CCO:B0056348 ! TIGD5_HUMAN relationship: location_of CCO:B0056844 ! Q6N011_HUMAN relationship: location_of CCO:B0056856 ! TIGD7_HUMAN relationship: location_of CCO:B0057289 ! Q86XJ5_HUMAN relationship: location_of CCO:B0057383 ! TIGD4_HUMAN relationship: location_of CCO:B0058286 ! Q96ME4_HUMAN relationship: location_of CCO:B0058295 ! TIGD1_HUMAN relationship: location_of CCO:B0063163 ! ZN330_HUMAN relationship: location_of CCO:B0064292 ! CENPU_HUMAN-Phosphoserine111 relationship: location_of CCO:B0067362 ! KIF2C_HUMAN-Phosphoserine106 relationship: location_of CCO:B0071003 ! SUV92_HUMAN-Phosphoserine381 [Term] id: CCO:C0002169 name: condensed chromosome, centromeric region namespace: cellular_component def: "The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome." [GOC:elh, GOC:kva] comment: Note that this term can be used in place of the obsoleted cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. synonym: "condensed chromosome, centric region" EXACT [] synonym: "condensed chromosome, centromere" RELATED [] synonym: "condensed chromosome, pericentric region" RELATED [] xref: GO:0000779 is_a: CCO:C0002168 ! chromosome, centromeric region relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 relationship: part_of CCO:C0000120 ! condensed chromosome [Term] id: CCO:C0002170 name: condensed nuclear chromosome, centromeric region namespace: cellular_component def: "The region of a condensed chromosome in the nucleus that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome." [GOC:elh, GOC:kva] comment: Note that this term can be used in place of the obsoleted cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex. synonym: "condensed nuclear chromosome, centric region" EXACT [] synonym: "condensed nuclear chromosome, centromere" RELATED [] synonym: "condensed nuclear chromosome, pericentric region" RELATED [] xref: GO:0000780 is_a: CCO:C0001873 ! nuclear chromosome part is_a: CCO:C0002169 ! condensed chromosome, centromeric region relationship: part_of CCO:C0000121 ! condensed nuclear chromosome [Term] id: CCO:C0002171 name: centromeric heterochromatin namespace: cellular_component def: "A region of heterochromatin located near the centromere of a chromosome." [PMID:12019236] synonym: "centric heterochromatin" EXACT [] xref: GO:0005721 is_a: CCO:C0000119 ! heterochromatin relationship: location_of CCO:B0002161 ! HELLS_HUMAN relationship: location_of CCO:B0012399 ! INCE_HUMAN-Phosphoserine296 relationship: location_of CCO:B0063758 ! BAZ1B_HUMAN-Phosphoserine347 relationship: part_of CCO:C0002168 ! chromosome, centromeric region [Term] id: CCO:C0002172 name: mRNA cap binding complex namespace: cellular_component def: "Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA." [GOC:jic] synonym: "mRNA cap complex" RELATED [] xref: GO:0005845 is_a: CCO:C0001843 ! intracellular part is_a: CCO:C0002194 ! RNA cap binding complex relationship: location_of CCO:B0063016 ! NCBP2_HUMAN relationship: location_of CCO:B0068452 ! NCBP1_HUMAN-Phosphoserine22 [Term] id: CCO:C0002173 name: NAD(P)H dehydrogenase complex (plastoquinone) namespace: cellular_component def: "Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool." [PMID:15608332] xref: GO:0010598 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part is_a: CCO:C0001844 ! membrane part [Term] id: CCO:C0002174 name: nuclear centromeric heterochromatin namespace: cellular_component def: "A region of heterochromatin located near the centromere of a chromosome in the nucleus." [GOC:mah] synonym: "nuclear centric heterochromatin" EXACT [] xref: GO:0031618 is_a: CCO:C0000310 ! nuclear heterochromatin is_a: CCO:C0002171 ! centromeric heterochromatin relationship: location_of CCO:B0064100 ! CBX3_HUMAN-Phosphoserine176 [Term] id: CCO:C0002175 name: small-subunit processome namespace: cellular_component def: "A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins." [PMID:12068309, PMID:12957375, PMID:15120992, PMID:15590835] synonym: "small subunit processome" EXACT [] synonym: "SSU processome" EXACT [] xref: GO:0032040 is_a: CCO:C0001044 ! nucleolar preribosome relationship: location_of CCO:B0001882 ! UT14C_HUMAN relationship: location_of CCO:B0013960 ! SAS10_HUMAN-Phosphoserine368 relationship: location_of CCO:B0014589 ! UT14A_HUMAN-Phosphoserine445 relationship: location_of CCO:B0057591 ! NGDN_HUMAN relationship: location_of CCO:B0059334 ! UTP11_HUMAN relationship: location_of CCO:B0071838 ! WDR3_HUMAN-Phosphotyrosine723 [Term] id: CCO:C0002176 name: EGO complex namespace: cellular_component def: "A vacuolar membrane-associated protein complex that is required for activation of microautophagy during exit from rapamycin-induced growth arrest. In budding yeast, S. cerevisiae, this complex includes Meh1p, Gtr2p and Slm4p." [GOC:rb, PMID:15989961] xref: GO:0034448 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000356 ! vacuolar membrane [Term] id: CCO:C0002177 name: GSE complex namespace: cellular_component def: "A conserved protein complex required for protein sorting from endosome to the plasma membrane. In budding yeast, S. cerevisiae, this complex includes Gtr1p, Gtr2p, Slm4p, Meh1p and Ltv1p and it sorts Gap1p." [GOC:rb, PMID:15989961] synonym: "GTPase-containing complex for Gap1p sorting in the endosome" EXACT [] xref: GO:0034449 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000351 ! endosome [Term] id: CCO:C0002178 name: centriolar satellite namespace: cellular_component def: "A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; cetriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome." [PMID:10579718, PMID:12403812] xref: GO:0034451 is_a: CCO:C0001849 ! cytoskeletal part is_a: CCO:C0001869 ! microtubule organizing center part relationship: location_of CCO:B0012464 ! K1C18_HUMAN-Phosphoserine15 relationship: location_of CCO:B0031661 ! PAX2_HUMAN relationship: location_of CCO:B0043836 ! BBS4_HUMAN relationship: location_of CCO:B0062769 ! EXOC7_HUMAN relationship: location_of CCO:B0066214 ! FLOT1_HUMAN-Phosphotyrosine203 relationship: part_of CCO:C0000383 ! centrosome [Term] id: CCO:C0002179 name: t-UTP complex namespace: cellular_component def: "A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p." [GOC:mah, PMID:17515605] comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. synonym: "Nan1p-containing subcomplex of 90S preribosome" EXACT [] xref: GO:0034455 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001871 ! nucleolar part relationship: part_of CCO:C0001045 ! 90S preribosome [Term] id: CCO:C0002180 name: UTP-C complex namespace: cellular_component def: "A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p." [GOC:mah, PMID:17515605] comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. synonym: "Rrp7p-containing subcomplex of 90S preribosome" EXACT [] xref: GO:0034456 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001871 ! nucleolar part relationship: part_of CCO:C0001045 ! 90S preribosome [Term] id: CCO:C0002181 name: Mpp10 complex namespace: cellular_component def: "A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p." [GOC:mah, PMID:17515605] comment: Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found. xref: GO:0034457 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001871 ! nucleolar part relationship: part_of CCO:C0001045 ! 90S preribosome [Term] id: CCO:C0002182 name: BBSome namespace: cellular_component def: "A protein complex that associates with the primary cilium and is involved in cilium biogenesis; consists of seven conserved proteins: BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 and BBS9." [PMID:17574030] synonym: "Bardet-Biedl syndrome complex" EXACT [] xref: GO:0034464 is_a: CCO:C0001750 ! protein complex relationship: location_of CCO:B0043419 ! BBS2_HUMAN relationship: location_of CCO:B0043836 ! BBS4_HUMAN [Term] id: CCO:C0002183 name: chromaffin granule lumen namespace: cellular_component def: "The volume enclosed by the membrane of a chromaffin granule." [GOC:rph] xref: GO:0034466 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0001656 ! chromaffin granule [Term] id: CCO:C0002184 name: esterosome lumen namespace: cellular_component def: "The volume enclosed by the membrane of an esterosome." [GOC:rph] xref: GO:0034467 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0001535 ! esterosome [Term] id: CCO:C0002185 name: glycosome lumen namespace: cellular_component def: "The volume enclosed by the membrane of a glycosome." [GOC:rph] xref: GO:0034468 is_a: CCO:C0001749 ! organelle lumen relationship: part_of CCO:C0000914 ! glycosome [Term] id: CCO:C0002186 name: Golgi stack lumen namespace: cellular_component def: "The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex." [GOC:mah] xref: GO:0034469 is_a: CCO:C0000377 ! Golgi lumen relationship: part_of CCO:C0000376 ! Golgi stack [Term] id: CCO:C0002187 name: hydrogenosome lumen namespace: cellular_component def: "The volume enclosed by the hydrogenosome membrane." [GOC:rph] xref: GO:0034492 is_a: CCO:C0001749 ! organelle lumen relationship: part_of CCO:C0001647 ! hydrogenosome [Term] id: CCO:C0002188 name: melanosome lumen namespace: cellular_component def: "The volume enclosed by the melanosome membrane." [GOC:rph] xref: GO:0034493 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0001642 ! melanosome [Term] id: CCO:C0002189 name: microneme lumen namespace: cellular_component def: "The volume enclosed by the microneme membrane." [GOC:rph] xref: GO:0034494 is_a: CCO:C0001749 ! organelle lumen relationship: part_of CCO:C0000911 ! microneme [Term] id: CCO:C0002190 name: protein storage vacuole lumen namespace: cellular_component def: "The volume enclosed by the protein storage vacuole membrane." [GOC:rph] xref: GO:0034495 is_a: CCO:C0002155 ! plant-type vacuole lumen relationship: part_of CCO:C0000064 ! protein storage vacuole [Term] id: CCO:C0002191 name: chromosome, centromeric core region namespace: cellular_component def: "The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it." [GOC:mah, GOC:val] synonym: "chromosome, centric core region" RELATED [] xref: GO:0034506 is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0002168 ! chromosome, centromeric region [Term] id: CCO:C0002192 name: chromosome, centromeric outer repeat region namespace: cellular_component def: "The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it." [GOC:mah, GOC:val] synonym: "chromosome, centric outer repeat region" RELATED [] xref: GO:0034507 is_a: CCO:C0001846 ! chromosomal part relationship: part_of CCO:C0002168 ! chromosome, centromeric region [Term] id: CCO:C0002193 name: proteasome storage granule namespace: cellular_component def: "A multisubunit proteasome complex that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state." [GOC:rb, PMID:18504300] synonym: "PSG" EXACT [] xref: GO:0034515 is_a: CCO:C0002092 ! cytosolic proteasome complex [Term] id: CCO:C0002194 name: RNA cap binding complex namespace: cellular_component def: "Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA." [GOC:mah] xref: GO:0034518 is_a: CCO:C0001750 ! protein complex [Term] id: CCO:C0002195 name: cytoplasmic RNA cap binding complex namespace: cellular_component def: "A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA." [PMID:16405910] xref: GO:0034519 is_a: CCO:C0002194 ! RNA cap binding complex [Term] id: CCO:C0002196 name: rhoptry lumen namespace: cellular_component def: "The volume enclosed by the rhoptry membrane." [GOC:rph, PMID:17997128] xref: GO:0034591 is_a: CCO:C0001749 ! organelle lumen relationship: part_of CCO:C0000910 ! rhoptry [Term] id: CCO:C0002197 name: synaptic vesicle lumen namespace: cellular_component def: "The volume enclosed by the synaptic vesicle membrane." [GOC:rph] xref: GO:0034592 is_a: CCO:C0002132 ! cytoplasmic membrane-bounded vesicle lumen relationship: part_of CCO:C0000522 ! synaptic vesicle [Term] id: CCO:C0002198 name: GCH1 complex namespace: cellular_component def: "A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive." [PMID:16696853] synonym: "GTP cyclohydrolase I complex" EXACT [] xref: GO:0034615 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001843 ! intracellular part [Term] id: CCO:C0002199 name: organelle-enclosing lipid monolayer namespace: cellular_component def: "A lipid monolayer that surrounds and encloses an organelle." [GOC:mah] xref: GO:0034646 is_a: CCO:C0001865 ! intracellular organelle part [Term] id: CCO:C0002200 name: Tpg-containing telomere binding complex namespace: cellular_component def: "A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species." [PMID:15353591] subset: gosubset_prok synonym: "telomere complex" BROAD [] xref: GO:0043769 is_a: CCO:C0000109 ! telomere cap complex [Term] id: CCO:C0002201 name: DNA polymerase III, proofreading complex namespace: cellular_component def: "A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity." [http://en.wikipedia.org/wiki/Pol_III, IMG:01721] subset: gosubset_prok synonym: "DNA polymerase III, proof-reading complex" EXACT [] synonym: "DNA polymerase III, proof-reading subcomplex" EXACT [] synonym: "DNA polymerase III, proofreading subcomplex" EXACT [] xref: GO:0043845 is_a: CCO:C0001750 ! protein complex relationship: part_of CCO:C0000604 ! DNA polymerase III complex [Term] id: CCO:C0002202 name: chromosome segregation-directing complex namespace: cellular_component def: "A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology." [GOC:jl, PMID:15612918] subset: gosubset_prok synonym: "chromosome segregation directing complex" EXACT [] synonym: "longitudinal peptidoglycan synthesis-directing complex" EXACT [] synonym: "MreBCD complex" NARROW [] xref: GO:0043913 xref: IMG:02994 is_a: CCO:C0001750 ! protein complex is_a: CCO:C0001844 ! membrane part [Term] id: CCO:C0002203 name: microtubule-associated DASH complex namespace: cellular_component def: "A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex associates with microtubules and plays a role in spindle attachment, chromosome segregation and spindle stability." [GOC:jl, GOC:mtg_mpo, PMID:11782438, PMID:11799062] comment: Note that this complex is conserved in fungi but has not been observed in metazoans. xref: GO:0043925 is_a: CCO:C0000435 ! microtubule associated complex is_a: CCO:C0001694 ! DASH complex relationship: part_of CCO:C0000396 ! kinetochore microtubule [Term] id: CCO:C0002204 name: kinetochore-associated DASH complex namespace: cellular_component def: "A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex associates with kinetochores and plays a role in spindle attachment, chromosome segregation and spindle stability." [GOC:jl, GOC:mtg_mpo, PMID:11782438, PMID:11799062] comment: Note that this complex is conserved in fungi but has not been observed in metazoans. synonym: "condensed nuclear chromosome kinetochore-associated DASH complex" EXACT [] xref: GO:0043926 is_a: CCO:C0001694 ! DASH complex relationship: part_of CCO:C0000105 ! condensed nuclear chromosome kinetochore [Term] id: CCO:F0000001 name: high affinity zinc uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+(out) = Zn2+(in), probably powered by proton motive force. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:2.A.5.1.1] xref: GO:0000006 is_a: CCO:F0001601 ! zinc ion transmembrane transporter activity [Term] id: CCO:F0000002 name: low-affinity zinc ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0000007 is_a: CCO:F0001601 ! zinc ion transmembrane transporter activity [Term] id: CCO:F0000003 name: alpha-1,6-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,6-linkage." [GOC:mcc, PMID:2644248] xref: EC:2.4.1.- xref: GO:0000009 is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000004 name: trans-hexaprenyltranstransferase activity namespace: molecular_function def: "Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = diphosphate + all-trans-heptaprenyl diphosphate." [EC:2.5.1.30] subset: gosubset_prok synonym: "all-trans-heptaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.30] synonym: "all-trans-hexaprenyl-diphosphate:isopentenyl-diphosphate hexaprenyltranstransferase activity" EXACT [EC:2.5.1.30] synonym: "heptaprenyl diphosphate synthase activity" EXACT [EC:2.5.1.30] synonym: "heptaprenyl pyrophosphate synthase activity" EXACT [EC:2.5.1.30] synonym: "heptaprenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.30] xref: EC:2.5.1.30 xref: GO:0000010 xref: MetaCyc:TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000005 name: single-stranded DNA specific endodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks." [GOC:mah] xref: GO:0000014 is_a: CCO:F0000917 ! endodeoxyribonuclease activity [Term] id: CCO:F0000006 name: lactase activity namespace: molecular_function def: "Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose." [EC:3.2.1.108] synonym: "lactase-phlorizin hydrolase activity" BROAD [EC:3.2.1.108] synonym: "lactose galactohydrolase activity" EXACT [EC:3.2.1.108] xref: EC:3.2.1.108 xref: GO:0000016 xref: MetaCyc:LACTASE-RXN xref: Reactome:20536 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0000007 name: alpha-1,2-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage." [GOC:mcc, PMID:10521541] xref: EC:2.4.1.- xref: GO:0000026 is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000008 name: mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] subset: gosubset_prok xref: EC:2.4.1.- xref: GO:0000030 xref: Reactome:7672 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0000009 name: mannosylphosphate transferase activity namespace: molecular_function def: "Catalysis of the transfer of an mannosylphosphate group from one compound to another." [GOC:jl] xref: GO:0000031 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0000010 name: alpha-1,3-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,3-linkage." [GOC:mcc, PMID:10521541] xref: EC:2.4.1.- xref: GO:0000033 is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000011 name: adenine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3." [EC:3.5.4.2] subset: gosubset_prok synonym: "ADase activity" EXACT [EC:3.5.4.2] synonym: "adenase activity" EXACT [EC:3.5.4.2] synonym: "adenine aminase activity" EXACT [EC:3.5.4.2] synonym: "adenine aminohydrolase activity" EXACT [EC:3.5.4.2] xref: EC:3.5.4.2 xref: GO:0000034 xref: MetaCyc:ADENINE-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000012 name: acyl binding namespace: molecular_function def: "Interacting selectively with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid." [http://cancerweb.ncl.ac.uk/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "acyl-CoA or acyl binding" BROAD [] xref: GO:0000035 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000013 name: acyl carrier activity namespace: molecular_function def: "Enables the directed movement of acyl groups into, out of, within or between cells." [ChEBI:22221, GOC:cb] subset: gosubset_prok xref: GO:0000036 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0000014 name: peptidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2)." [EC:2.3.2.12, PMID:11433365, PMID:9242921] synonym: "peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity" EXACT [EC:2.3.2.12] xref: EC:2.3.2.12 xref: GO:0000048 xref: MetaCyc:PEPTIDYLTRANSFERASE-RXN xref: Reactome:20610 is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0000015 name: tRNA binding namespace: molecular_function def: "Interacting selectively with transfer RNA." [GOC:ai] subset: gosubset_prok xref: GO:0000049 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0000016 name: acyl-CoA binding namespace: molecular_function def: "Interacting selectively with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "acyl-CoA or acyl binding" BROAD [] xref: GO:0000062 is_a: CCO:F0001642 ! fatty acid binding is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0000017 name: L-ornithine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "histidine/arginine/lysine/ornithine porter activity" RELATED [] synonym: "L-ornithine transporter activity" BROAD [] xref: GO:0000064 xref: Reactome:20635 is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0000018 name: S-adenosylmethionine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism." [GOC:ai] synonym: "S-adenosyl methionine permease activity" EXACT [] synonym: "S-adenosyl methionine transporter activity" EXACT [] synonym: "S-adenosylmethionine permease activity" EXACT [] synonym: "S-adenosylmethionine transporter activity" BROAD [] xref: GO:0000095 xref: GO:0015177 is_a: CCO:F0000019 ! sulfur amino acid transmembrane transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0000019 name: sulfur amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "sulfur amino acid transporter activity" BROAD [] synonym: "sulphur amino acid transmembrane transporter activity" EXACT [] synonym: "sulphur amino acid transporter activity" BROAD [] xref: GO:0000099 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0000020 name: S-methylmethionine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of S-methylmethionine from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "S-methylmethionine permease activity" EXACT [] synonym: "S-methylmethionine transporter activity" BROAD [] xref: GO:0000100 xref: GO:0015178 is_a: CCO:F0000019 ! sulfur amino acid transmembrane transporter activity [Term] id: CCO:F0000021 name: L-methionine secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] synonym: "L-methionine porter activity" RELATED [] xref: GO:0000102 is_a: CCO:F0001541 ! neutral L-amino acid secondary active transmembrane transporter activity is_a: CCO:F0002665 ! L-methionine transmembrane transporter activity [Term] id: CCO:F0000022 name: succinate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols." [EC:1.3.99.1, GOC:kd] subset: gosubset_prok synonym: "fumarate dehydrogenase activity" EXACT [EC:1.3.99.1] synonym: "fumarate reductase activity" EXACT [EC:1.3.99.1] synonym: "fumaric hydrogenase activity" EXACT [EC:1.3.99.1] synonym: "succinate oxidoreductase activity" EXACT [EC:1.3.99.1] synonym: "succinate:(acceptor) oxidoreductase activity" EXACT [EC:1.3.99.1] synonym: "succinate:acceptor oxidoreductase activity" EXACT [EC:1.3.99.1] synonym: "succinic acid dehydrogenase activity" EXACT [EC:1.3.99.1] synonym: "succinic dehydrogenase activity" BROAD [EC:1.3.99.1] synonym: "succinodehydrogenase activity" EXACT [EC:1.3.99.1] synonym: "succinyl dehydrogenase activity" EXACT [EC:1.3.99.1] xref: EC:1.3.99.1 xref: GO:0000104 xref: GO:0019739 xref: MetaCyc:SUCC-FUM-OXRED-RXN xref: Reactome:21566 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0000023 name: imidazoleglycerol-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + AICAR + L-glutamate." [MetaCyc:GLUTAMIDOTRANS-RXN] subset: gosubset_prok synonym: "glutamine amidotransferase:cyclase activity" BROAD [] synonym: "imidazole glycerol phosphate synthase activity" EXACT [] synonym: "imidazole-glycerol-phosphate synthase activity" RELATED [] synonym: "imidazoleglycerol phosphate synthase activity" EXACT [] xref: EC:2.4.2.- xref: GO:0000107 xref: MetaCyc:GLUTAMIDOTRANS-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000024 name: glycerol-1-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol 1-phosphate + H2O = glycerol + phosphate." [EC:3.1.3.21] synonym: "alpha-glycerol phosphatase activity" EXACT [EC:3.1.3.21] synonym: "alpha-glycerophosphatase activity" EXACT [EC:3.1.3.21] synonym: "glycerol 3-phosphatase activity" EXACT [EC:3.1.3.21] synonym: "glycerol 3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.21] synonym: "glycerol-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.21] synonym: "glycerol-3-phosphate phosphatase activity" EXACT [EC:3.1.3.21] xref: EC:3.1.3.21 xref: GO:0000121 xref: MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000025 name: acylglycerone-phosphate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 1-palmitoylglycerol 3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H+." [EC:1.1.1.101] synonym: "1-acyldihydroxyacetone-phosphate reductase activity" EXACT [] synonym: "1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.101] synonym: "acyldihydroxyacetone phosphate reductase activity" EXACT [EC:1.1.1.101] synonym: "palmitoyl dihydroxyacetone phosphate reductase activity" EXACT [EC:1.1.1.101] synonym: "palmitoyl-dihydroxyacetone-phosphate reductase activity" EXACT [EC:1.1.1.101] synonym: "palmitoyldihydroxyacetone-phosphate reductase activity" EXACT [EC:1.1.1.101] xref: EC:1.1.1.101 xref: GO:0000140 xref: MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN xref: Reactome:21659 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000026 name: microfilament motor activity namespace: molecular_function def: "Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)." [GOC:mah, ISBN:0815316194] synonym: "actin filament motor activity" EXACT [GOC:dph] synonym: "actin-filament motor activity" EXACT [] synonym: "muscle motor activity" NARROW [] synonym: "myosin ATPase activity" RELATED [] xref: GO:0000146 is_a: CCO:F0000321 ! motor activity [Term] id: CCO:F0000027 name: SNARE binding namespace: molecular_function def: "Interacting selectively with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein." [PMID:12642621] synonym: "SNAP receptor binding" EXACT [] xref: GO:0000149 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000028 name: recombinase activity namespace: molecular_function def: "Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA." [GOC:elh] comment: Consider also annotating to the molecular function terms 'double-stranded DNA binding ; GO:0003690' and 'single-stranded DNA binding ; GO:0003697'. Note that this term represents activities that do not break or form phosphodiester bonds, and is therefore not a parent of 'site-specific recombinase activity ; GO:0009009'. subset: gosubset_prok synonym: "strand transferase" NARROW [] xref: GO:0000150 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0000029 name: two-component sensor activity namespace: molecular_function def: "Catalysis of the phosphorylation of a specific transcription regulator in response to the presence of a particular signal substance outside the cell." [GOC:mah] subset: gosubset_prok synonym: "two-component sensor molecule" NARROW [] synonym: "two-component system sensor activity " EXACT [] xref: EC:2.7.3.- xref: GO:0000155 is_a: CCO:F0001044 ! protein histidine kinase activity is_a: CCO:F0001225 ! signal transducer activity [Term] id: CCO:F0000030 name: two-component response regulator activity namespace: molecular_function def: "Alters the level of transcription of target genes, usually by binding to a transcription factor, when phosphorylated by a sensor that detects the presence of a particular signal substance outside the cell." [GOC:mah] subset: gosubset_prok xref: GO:0000156 is_a: CCO:F0001225 ! signal transducer activity is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000031 name: nucleotide binding namespace: molecular_function def: "Interacting selectively with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose moiety." [GOC:mah, ISBN:0198547684] subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: gosubset_prok xref: GO:0000166 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000032 name: sphingosine hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of sphingolipid long chain bases." [PMID:9556590] xref: GO:0000170 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0000033 name: ribonuclease MRP activity namespace: molecular_function def: "Catalysis of the site-specific cleavage of RNA by a catalytic RNA_mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA." [PMID:17881380] synonym: "RNase MRP" EXACT [] xref: GO:0000171 is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0000034 name: 3'-5'-exoribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule." [GOC:mah, ISBN:0198547684] subset: gosubset_prok synonym: "3'-5' exoribonuclease activity" EXACT [] xref: EC:3.1.13.- xref: GO:0000175 is_a: CCO:F0001875 ! 3'-5' exonuclease activity is_a: CCO:F0003454 ! exoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000035 name: rRNA (adenine-N6,N6-)-dimethyltransferase activity namespace: molecular_function def: "Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor." [ISBN:1555811337 "Modification and Editing of RNA", PMID:10690410] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0000179 is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0003155 ! rRNA (adenine) methyltransferase activity [Term] id: CCO:F0000036 name: rDNA binding namespace: molecular_function def: "Interacting selectively with DNA sequences encoding ribosomal RNA." [GOC:mah] synonym: "ribosomal DNA binding" EXACT [] xref: GO:0000182 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0000037 name: NAD+ diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + H2O = AMP + NMN." [EC:3.6.1.22] subset: gosubset_prok synonym: "NAD diphosphatase activity" EXACT [] synonym: "NAD pyrophosphatase activity" EXACT [] synonym: "NAD(+) pyrophosphatase activity" EXACT [EC:3.6.1.22] synonym: "NAD+ phosphohydrolase activity" EXACT [EC:3.6.1.22] synonym: "NAD+ pyrophosphatase activity" EXACT [EC:3.6.1.22] synonym: "NADH pyrophosphatase activity" EXACT [EC:3.6.1.22] synonym: "NADP pyrophosphatase activity" EXACT [EC:3.6.1.22] synonym: "nicotinamide adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.22] xref: EC:3.6.1.22 xref: GO:0000210 xref: MetaCyc:NADPYROPHOSPHAT-RXN is_a: CCO:F0000937 ! nucleotide diphosphatase activity [Term] id: CCO:F0000038 name: tRNA-intron endonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron." [EC:3.1.27.9] synonym: "splicing endonuclease activity" EXACT [EC:3.1.27.9] synonym: "transfer ribonucleate intron endoribonuclease activity" EXACT [EC:3.1.27.9] synonym: "transfer splicing endonuclease activity" EXACT [EC:3.1.27.9] synonym: "tRNA splicing endonuclease activity" EXACT [EC:3.1.27.9] synonym: "tRNA-intron endoribonuclease activity" EXACT [] synonym: "tRNA-splicing endonuclease activity" EXACT [EC:3.1.27.9] synonym: "tRNATRPintron endonuclease activity" EXACT [EC:3.1.27.9] xref: EC:3.1.27.9 xref: GO:0000213 xref: MetaCyc:3.1.27.9-RXN is_a: CCO:F0000935 ! tRNA-specific ribonuclease activity is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0000039 name: tRNA 2'-phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O; transfers the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate." [EC:2.7.1.160, PMID:9148937] synonym: "2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity" EXACT [EC:2.7.1.160] synonym: "2'-phospho-tRNA:NAD+ phosphotransferase activity" EXACT [EC:2.7.1.160] synonym: "Tpt1" RELATED [EC:2.7.1.160] synonym: "Tpt1p" RELATED [EC:2.7.1.160] synonym: "yeast 2'-phosphotransferase activity" NARROW [EC:2.7.1.160] xref: EC:2.7.1.160 xref: GO:0000215 is_a: CCO:F0002025 ! 2'-phosphotransferase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000040 name: DNA secondary structure binding namespace: molecular_function def: "Interacting selectively with DNA containing secondary structure elements such as four-way junctions, bubbles, loops, Y-form DNA, or double-strand/single-strand junctions." [GOC:krc] xref: GO:0000217 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0000041 name: peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue." [EC:3.5.1.52] subset: gosubset_prok synonym: "glycopeptidase activity" BROAD [EC:3.5.1.52] synonym: "glycopeptide N-glycosidase activity" BROAD [EC:3.5.1.52] synonym: "jack-bean glycopeptidase" NARROW [EC:3.5.1.52] synonym: "N-glycanase activity" RELATED [EC:3.5.1.52] synonym: "N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.52] synonym: "N-oligosaccharide glycopeptidase activity" RELATED [EC:3.5.1.52] synonym: "peptide:N-glycanase" RELATED [] synonym: "PNGase" EXACT [] synonym: "PNGase A" RELATED [EC:3.5.1.52] synonym: "PNGase F" RELATED [EC:3.5.1.52] xref: EC:3.5.1.52 xref: GO:0000224 xref: MetaCyc:3.5.1.52-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000042 name: N-acetylglucosaminylphosphatidylinositol deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. The second step enzyme catalyzing the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane. Catalyzes the N-deacetylation of GlcNAc-PI to GlcN-PI." [EC:3.5.1.89] comment: Note that this function was formerly EC:3.1.1.69. synonym: "6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity" EXACT [EC:3.5.1.89] synonym: "acetylglucosaminylphosphatidylinositol deacetylase activity" EXACT [EC:3.5.1.89] synonym: "GlcNAc-PI de-N-acetylase activity" EXACT [EC:3.5.1.89] synonym: "GlcNAc-PI deacetylase activity" EXACT [EC:3.5.1.89] synonym: "N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity" EXACT [EC:3.5.1.89] synonym: "N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity" EXACT [EC:3.5.1.89] xref: EC:3.5.1.89 xref: GO:0000225 xref: MetaCyc:3.1.1.69-RXN xref: Reactome:22619 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0000043 name: oxaloacetate secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] synonym: "oxaloacetate carrier activity" RELATED [] xref: GO:0000227 is_a: CCO:F0002608 ! oxaloacetate transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0000044 name: phosphoethanolamine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate." [EC:2.1.1.103] synonym: "phosphoethanolamine methyltransferase activity" EXACT [EC:2.1.1.103] synonym: "S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity" EXACT [EC:2.1.1.103] xref: EC:2.1.1.103 xref: GO:0000234 xref: MetaCyc:2.1.1.103-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0000045 name: delta24(24-1) sterol reductase activity namespace: molecular_function def: "Catalysis of the reaction: ergosterol + NADP+ = ergosta-5,7,22,24(241)-tetraen-3-beta-ol + NADPH + H+." [EC:1.3.1.71, PMID:10722850] subset: gosubset_prok synonym: "C-24(28) sterol reductase activity" EXACT [EC:1.3.1.71] synonym: "D24(24-1)-sterol reductase activity" EXACT [] synonym: "delta24(241)-sterol reductase activity" EXACT [EC:1.3.1.71] synonym: "ergosterol:NADP+ delta24(241)-oxidoreductase activity" EXACT [EC:1.3.1.71] synonym: "sterol Delta(24(28))-methylene reductase activity" EXACT [EC:1.3.1.71] synonym: "sterol Delta(24(28))-reductase activity" EXACT [EC:1.3.1.71] synonym: "sterol delta-24(28) methylene reductase activity" EXACT [] synonym: "sterol delta-24(28) reductase activity" EXACT [] synonym: "sterol delta24(28)-methylene reductase activity" EXACT [EC:1.3.1.71] synonym: "sterol delta24(28)-reductase activity" EXACT [EC:1.3.1.71] xref: EC:1.3.1.71 xref: GO:0000246 xref: MetaCyc:1.3.1.71-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000046 name: C-8 sterol isomerase activity namespace: molecular_function def: "Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols." [UniProtKB:P32352] synonym: "delta-8-delta-7 sterol isomerase activity" EXACT [] xref: EC:5.3.3.- xref: GO:0000247 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0000047 name: C-5 sterol desaturase activity namespace: molecular_function def: "Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+." [MetaCyc:RXN3O-227] synonym: "sterol-C5-desaturase activity" EXACT [] xref: GO:0000248 is_a: CCO:F0003300 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Term] id: CCO:F0000048 name: C-22 sterol desaturase activity namespace: molecular_function def: "Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction is 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+." [MetaCyc:RXN3O-227, UniProtKB:P54781] xref: GO:0000249 is_a: CCO:F0003300 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Term] id: CCO:F0000049 name: lanosterol synthase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus." [EC:5.4.99.7] subset: gosubset_prok synonym: "(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)" EXACT [EC:5.4.99.7] synonym: "2,3-epoxysqualene lanosterol cyclase activity" EXACT [EC:5.4.99.7] synonym: "2,3-epoxysqualene--lanosterol cyclase activity" EXACT [EC:5.4.99.7] synonym: "2,3-epoxysqualene-lanosterol cyclase activity" EXACT [] synonym: "2,3-oxidosqualene cyclase activity" EXACT [EC:5.4.99.7] synonym: "2,3-oxidosqualene sterol cyclase activity" EXACT [EC:5.4.99.7] synonym: "2,3-oxidosqualene-lanosterol cyclase activity" EXACT [EC:5.4.99.7] synonym: "lanosterol 2,3-oxidosqualene cyclase activity" EXACT [EC:5.4.99.7] synonym: "OSC" EXACT [] synonym: "oxidosqualene--lanosterol cyclase activity" EXACT [EC:5.4.99.7] synonym: "oxidosqualene-lanosterol cyclase activity" EXACT [] synonym: "oxidosqualene:lanosterol cyclase activity" EXACT [PMID:18033581] synonym: "squalene 2,3-epoxide:lanosterol cyclase activity" EXACT [EC:5.4.99.7] synonym: "squalene epoxidase-cyclase activity" EXACT [EC:5.4.99.7] synonym: "squalene-2,3-oxide-lanosterol cyclase activity" EXACT [EC:5.4.99.7] xref: EC:5.4.99.7 xref: GO:0000250 xref: MetaCyc:LANOSTEROL-SYNTHASE-RXN xref: Reactome:22668 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0000050 name: C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity namespace: molecular_function def: "Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H." [EC:1.1.1.170, PMID:9811880] comment: Note that zymosterol is cholesta-8,24-dien-3-ol. synonym: "3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [EC:1.1.1.170] synonym: "3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)" EXACT [] synonym: "3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [] synonym: "3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity" RELATED [] synonym: "C-3 sterol dehydrogenase (C-4 decarboxylase) activity" RELATED [] synonym: "C-3 sterol dehydrogenase activity" RELATED [] synonym: "sterol 4alpha-carboxylic decarboxylase activity" RELATED [] synonym: "sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity" RELATED [] synonym: "sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)" RELATED [] xref: EC:1.1.1.- xref: GO:0000252 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000051 name: 3-keto sterol reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + NADPH + H+." [EC:1.1.1.270, PMID:9811880] comment: Note that zymosterol is cholesta-8,24-dien-3-ol. synonym: "3beta-hydroxy-steroid:NADP+ 3-oxidoreductase" RELATED [EC:1.1.1.270] xref: EC:1.1.1.- xref: GO:0000253 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000052 name: C-4 methylsterol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H+ + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O." [EC:1.14.13.72, PMID:9811880] comment: Note that zymosterol is cholesta-8,24-dien-3-ol. synonym: "4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.13.72] synonym: "4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.13.72] synonym: "4-methylsterol oxidase activity" EXACT [] synonym: "methylsterol hydroxylase activity" RELATED [] synonym: "methylsterol monooxygenase activity" RELATED [] xref: EC:1.14.13.72 xref: GO:0000254 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000053 name: nitrilase activity namespace: molecular_function def: "Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides." [EC:3.5.5.1, GOC:kd] subset: gosubset_prok synonym: "acetonitrilase activity" EXACT [EC:3.5.5.1] synonym: "benzonitrilase activity" EXACT [EC:3.5.5.1] synonym: "nitrile aminohydrolase activity" EXACT [EC:3.5.5.1] xref: EC:3.5.5.1 xref: GO:0000257 xref: MetaCyc:3.5.5.1-RXN xref: UM-BBD_enzymeID:e0283 is_a: CCO:F0003384 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles [Term] id: CCO:F0000054 name: peroxisome targeting sequence binding namespace: molecular_function def: "Interacting selectively with a peroxisomal targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome." [GOC:mah, ISBN:0879693568] synonym: "peroxisome targeting signal receptor" NARROW [] synonym: "PTS binding" EXACT [] synonym: "PTS receptor" NARROW [] xref: GO:0000268 xref: GO:0005051 is_a: CCO:F0001368 ! signal sequence binding [Term] id: CCO:F0000055 name: toxin export channel activity namespace: molecular_function def: "Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] xref: GO:0000269 is_a: CCO:F0002739 ! porin activity is_a: CCO:F0004142 ! toxin transporter activity [Term] id: CCO:F0000057 name: 1-phosphatidylinositol-3-phosphate 5-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate." [EC:2.7.1.150] synonym: "ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.150] synonym: "phosphatidylinositol 3-phosphate 5-kinase activity" EXACT [EC:2.7.1.150] synonym: "phosphatidylinositol-3-phosphate 5-kinase activity" EXACT [] synonym: "type III PIP kinase activity" RELATED [EC:2.7.1.150] xref: EC:2.7.1.150 xref: GO:0000285 xref: MetaCyc:2.7.1.150-RXN is_a: CCO:F0003116 ! phosphatidylinositol phosphate kinase activity [Term] id: CCO:F0000058 name: alanine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+." [EC:1.4.1.1] subset: gosubset_prok synonym: "AlaDH" RELATED [EC:1.4.1.1] synonym: "alanine oxidoreductase activity" EXACT [EC:1.4.1.1] synonym: "alpha-alanine dehydrogenase activity" EXACT [EC:1.4.1.1] synonym: "L-alanine dehydrogenase activity" EXACT [EC:1.4.1.1] synonym: "L-alanine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.1] synonym: "NAD-dependent alanine dehydrogenase activity" EXACT [EC:1.4.1.1] synonym: "NAD-linked alanine dehydrogenase activity" EXACT [EC:1.4.1.1] synonym: "NADH-dependent alanine dehydrogenase activity" EXACT [EC:1.4.1.1] xref: EC:1.4.1.1 xref: GO:0000286 xref: MetaCyc:ALANINE-DEHYDROGENASE-RXN is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0000059 name: magnesium ion binding namespace: molecular_function def: "Interacting selectively with magnesium (Mg) ions." [GOC:ai] subset: gosubset_prok synonym: "magnesium binding" EXACT [] xref: GO:0000287 is_a: CCO:F0006257 ! metal ion binding [Term] id: CCO:F0000060 name: ferric-chelate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H+." [EC:1.16.1.7] comment: Note that this function was formerly EC:1.6.99.13. synonym: "Fe(II):NAD+ oxidoreductase activity" EXACT [EC:1.16.1.7] synonym: "ferric chelate reductase activity" EXACT [EC:1.16.1.7] synonym: "iron chelate reductase activity" RELATED [EC:1.16.1.7] synonym: "NADH2:Fe3+ oxidoreductase activity" EXACT [EC:1.16.1.7] synonym: "NADH:Fe(3+) oxidoreductase activity" EXACT [EC:1.16.1.7] synonym: "NADH:Fe(3+)-EDTA reductase activity" EXACT [EC:1.16.1.7] synonym: "NADH:Fe3+ oxidoreductase activity" EXACT [EC:1.16.1.7] synonym: "NADH:Fe3+-EDTA reductase activity" EXACT [EC:1.16.1.7] xref: EC:1.16.1.7 xref: GO:0000293 xref: MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0000061 name: adenine nucleotide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of the membrane to the other." [PMID:11566870] xref: GO:0000295 is_a: CCO:F0002687 ! purine nucleotide transmembrane transporter activity [Term] id: CCO:F0000062 name: spermine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of spermine from one side of the membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication." [GOC:ai] xref: GO:0000297 is_a: CCO:F0002675 ! polyamine transmembrane transporter activity [Term] id: CCO:F0000063 name: endopolyphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues." [EC:3.6.1.10] synonym: "metaphosphatase activity" BROAD [EC:3.6.1.10] synonym: "polymetaphosphatase activity" EXACT [EC:3.6.1.10] synonym: "polyphosphatase activity" BROAD [EC:3.6.1.10] synonym: "polyphosphate depolymerase activity" BROAD [EC:3.6.1.10] synonym: "polyphosphate polyphosphohydrolase activity" EXACT [EC:3.6.1.10] xref: EC:3.6.1.10 xref: GO:0000298 xref: MetaCyc:ENDOPOLYPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0000064 name: nicotinamide-nucleotide adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+." [EC:2.7.7.1] subset: gosubset_prok synonym: "adenosine triphosphate-nicotinamide mononucleotide transadenylase activity" EXACT [EC:2.7.7.1] synonym: "ATP:nicotinamide-nucleotide adenylyltransferase activity" EXACT [] synonym: "ATP:NMN adenylyltransferase activity" EXACT [EC:2.7.7.1] synonym: "diphosphopyridine nucleotide pyrophosphorylase activity" RELATED [EC:2.7.7.1] synonym: "NAD(+) diphosphorylase activity" NARROW [EC:2.7.7.1] synonym: "NAD(+) pyrophosphorylase activity" NARROW [EC:2.7.7.1] synonym: "NAD+ diphosphorylase activity" EXACT [EC:2.7.7.1] synonym: "NAD+ pyrophosphorylase activity" EXACT [EC:2.7.7.1] synonym: "nicotinamide adenine dinucleotide pyrophosphorylase activity" NARROW [EC:2.7.7.1] synonym: "nicotinamide mononucleotide adenylyltransferase activity" NARROW [EC:2.7.7.1] synonym: "NMN adenylyltransferase activity" NARROW [EC:2.7.7.1] synonym: "NMNAT activity" NARROW [EC:2.7.7.1] xref: EC:2.7.7.1 xref: GO:0000309 xref: MetaCyc:2.7.7.1-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000065 name: xanthine phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate; substrate specificity for xanthine." [EC:2.4.2.22, GOC:clt] subset: gosubset_prok synonym: "5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.22] synonym: "Xan phosphoribosyltransferase activity" EXACT [EC:2.4.2.22] synonym: "xanthine-guanine phosphoribosyltransferase activity" EXACT [] synonym: "xanthosine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.22] synonym: "xanthylate pyrophosphorylase activity" EXACT [EC:2.4.2.22] synonym: "xanthylic pyrophosphorylase activity" EXACT [EC:2.4.2.22] synonym: "XMP pyrophosphorylase activity" EXACT [EC:2.4.2.22] synonym: "XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.22] xref: EC:2.4.2.22 xref: GO:0000310 xref: GO:0009043 xref: MetaCyc:XANPRIBOSYLTRAN-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000066 name: methionine-S-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine S-oxide + thioredoxin = L-methionine + thioredoxin disulfide. Thioredoxin disulfide is the oxidized form of thioredoxin. No reaction on oxidized methionine in peptide linkage." [PMID:11169920] subset: gosubset_prok synonym: "methionine sulfoxide reductase activity" EXACT [] xref: GO:0000317 xref: MetaCyc:METHIONINE-S-OXIDE-REDUCTASE-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0000067 name: protein-methionine-R-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin." [EC:1.8.4.-, PMID:11929995] subset: gosubset_prok synonym: "(protein) methionine-R-sulfoxide reductase activity" EXACT [] xref: EC:1.8.4.- xref: GO:0000318 is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0000068 name: sulfite transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sulfite ions from one side of a membrane to the other." [GOC:as] synonym: "sulphite transporter activity" EXACT [] xref: GO:0000319 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0000069 name: template for synthesis of G-rich strand of telomere DNA activity namespace: molecular_function def: "Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA." [PMID:11812242] synonym: "telomerase RNA" EXACT [] synonym: "telomerase, template" EXACT [] xref: GO:0000332 is_a: CCO:F0000090 ! base pairing with DNA relationship: part_of CCO:F0000306 ! telomerase activity [Term] id: CCO:F0000070 name: 3-hydroxyanthranilate 3,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde." [EC:1.13.11.6] subset: gosubset_prok synonym: "3-hydroxyanthranilate oxygenase activity" EXACT [EC:1.13.11.6] synonym: "3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.6] synonym: "3-hydroxyanthranilic acid dioxygenase activity" EXACT [EC:1.13.11.6] synonym: "3-hydroxyanthranilic acid oxygenase activity" EXACT [EC:1.13.11.6] synonym: "3-hydroxyanthranilic oxygenase activity" EXACT [EC:1.13.11.6] synonym: "3HAO" RELATED [EC:1.13.11.6] xref: EC:1.13.11.6 xref: GO:0000334 xref: MetaCyc:1.13.11.6-RXN xref: Reactome:23302 xref: UM-BBD_enzymeID:e0633 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0000071 name: RNA cap binding namespace: molecular_function def: "Interacting selectively with a 7-methylguanosine (m7G) moiety or derivative located at the 5' end of an RNA molecule." [GOC:krc] synonym: "binding to mRNA cap" NARROW [] synonym: "mRNA cap binding" NARROW [] synonym: "snRNA cap binding" NARROW [] xref: GO:0000339 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0000072 name: RNA 7-methylguanosine cap binding namespace: molecular_function def: "Interacting selectively with the 7-methylguanosine moiety added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II." [GOC:krc] synonym: "RNA m7G cap binding" EXACT [] xref: GO:0000340 is_a: CCO:F0000071 ! RNA cap binding [Term] id: CCO:F0000073 name: RNA trimethylguanosine cap binding namespace: molecular_function def: "Interacting selectively with the trimethylguanosine (m(3)(2,2,7)-GTP) moiety located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans." [GOC:krc] synonym: "RNA m2,2,7G cap binding" EXACT [] xref: GO:0000341 is_a: CCO:F0000071 ! RNA cap binding [Term] id: CCO:F0000074 name: RNA cap 4 binding namespace: molecular_function def: "Interacting selectively with a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa." [GOC:krc, PMID:10880518, PMID:12121975] xref: GO:0000342 is_a: CCO:F0000071 ! RNA cap binding [Term] id: CCO:F0000079 name: first spliceosomal transesterification activity namespace: molecular_function def: "Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon." [GOC:krc, ISBN:0879695897] synonym: "lariat formation, 5'-splice site cleavage" NARROW [] xref: GO:0000384 is_a: CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism [Term] id: CCO:F0000081 name: second spliceosomal transesterification activity namespace: molecular_function def: "Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure." [GOC:krc, ISBN:0879695897] synonym: "3'-splice site cleavage, exon ligation" BROAD [] synonym: "lariat formation, 5'-splice site cleavage" NARROW [] xref: GO:0000386 is_a: CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism [Term] id: CCO:F0000082 name: four-way junction DNA binding namespace: molecular_function def: "Interacting selectively with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices." [GOC:krc, ISBN:0815332181, PMID:15563464] synonym: "forked DNA binding" BROAD [] synonym: "Holliday junction binding" EXACT [] xref: GO:0000400 is_a: CCO:F0000040 ! DNA secondary structure binding [Term] id: CCO:F0000083 name: open form four-way junction DNA binding namespace: molecular_function def: "Interacting selectively with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over." [GOC:krc, ISBN:0815332181, PMID:15563464] synonym: "open form Holliday junction binding" EXACT [] xref: GO:0000401 is_a: CCO:F0000082 ! four-way junction DNA binding [Term] id: CCO:F0000084 name: crossed form four-way junction DNA binding namespace: molecular_function def: "Interacting selectively with DNA containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands." [GOC:krc, ISBN:0815332181, PMID:15563464] synonym: "crossed form Holliday junction binding" EXACT [] xref: GO:0000402 is_a: CCO:F0000082 ! four-way junction DNA binding [Term] id: CCO:F0000085 name: Y-form DNA binding namespace: molecular_function def: "Interacting selectively with segment of DNA shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end." [GOC:elh, PMID:16781730] synonym: "forked DNA binding" BROAD [] synonym: "slayed Y-form DNA binding" EXACT [] xref: GO:0000403 is_a: CCO:F0000040 ! DNA secondary structure binding [Term] id: CCO:F0000086 name: loop DNA binding namespace: molecular_function def: "Interacting selectively with DNA containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration." [GOC:elh, PMID:16781730] xref: GO:0000404 is_a: CCO:F0000040 ! DNA secondary structure binding is_a: CCO:F0004951 ! DNA insertion or deletion binding [Term] id: CCO:F0000087 name: bubble DNA binding namespace: molecular_function def: "Interacting selective with DNA that contains a bubble. A bubble occurs when DNA contains an region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA." [GOC:elh, PMID:16781730] xref: GO:0000405 is_a: CCO:F0000040 ! DNA secondary structure binding [Term] id: CCO:F0000088 name: double-strand/single-strand DNA junction binding namespace: molecular_function def: "Interacting selectively with a region of DNA that contains double-stranded DNA flanked by a region of single-stranded DNA." [GOC:elh, PMID:16781730] xref: GO:0000406 is_a: CCO:F0000040 ! DNA secondary structure binding [Term] id: CCO:F0000089 name: base pairing namespace: molecular_function def: "Interacting selectively with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target nucleic acid molecule." [GOC:krc] comment: Note that with respect to annotation, "base pairing" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with other nucleic acid molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. xref: GO:0000496 is_a: CCO:F0000273 ! nucleic acid binding [Term] id: CCO:F0000090 name: base pairing with DNA namespace: molecular_function def: "Interacting selectively with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule." [GOC:krc] comment: Note that with respect to annotation, "base pairing" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with DNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. xref: GO:0000497 is_a: CCO:F0000089 ! base pairing is_a: CCO:F0000274 ! DNA binding [Term] id: CCO:F0000091 name: base pairing with RNA namespace: molecular_function def: "Interacting selectively with ribonucleic acid (RNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target RNA molecule." [GOC:krc] comment: Note that with respect to annotation, "base pairing with RNA" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with other RNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. xref: GO:0000498 is_a: CCO:F0000089 ! base pairing is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0000092 name: base pairing with mRNA namespace: molecular_function def: "Interacting selectively with messenger ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target mRNA molecule." [GOC:krc] comment: Note that with respect to annotation, "base pairing with RNA" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with other RNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. xref: GO:0000499 is_a: CCO:F0000091 ! base pairing with RNA [Term] id: CCO:F0000093 name: mismatch base pair DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site." [GOC:elh, PMID:9224623] xref: GO:0000700 is_a: CCO:F0004051 ! DNA N-glycosylase activity [Term] id: CCO:F0000094 name: purine-specific mismatch base pair DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site." [GOC:elh, PMID:9224623] synonym: "A/G-specific adenine DNA glycosylase activity" NARROW [] xref: EC:3.2.2.- xref: GO:0000701 is_a: CCO:F0000093 ! mismatch base pair DNA N-glycosylase activity [Term] id: CCO:F0000095 name: oxidized base lesion DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site." [GOC:elh, PMID:11554296] subset: gosubset_prok xref: GO:0000702 is_a: CCO:F0004051 ! DNA N-glycosylase activity [Term] id: CCO:F0000096 name: oxidized pyrimidine base lesion DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site. Enzymes with this activity recognize and remove oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar." [GOC:elh, PMID:11554296] subset: gosubset_prok synonym: "bifunctional DNA glycosylase" BROAD [] synonym: "DNA glycosylase/AP-lyase" BROAD [] synonym: "DNA glycosylase/beta-lyase" BROAD [] synonym: "endodeoxyribonuclease III" RELATED [] synonym: "endonuclease III" RELATED [] synonym: "endonuclease VIII activity" RELATED [] synonym: "pyrimidine-specific oxidized base lesion DNA N-glycosylase activity" RELATED [] xref: GO:0000703 xref: GO:0019004 xref: Reactome:25087 is_a: CCO:F0000095 ! oxidized base lesion DNA N-glycosylase activity is_a: CCO:F0000411 ! DNA-(apurinic or apyrimidinic site) lyase activity is_a: CCO:F0000917 ! endodeoxyribonuclease activity [Term] id: CCO:F0000097 name: pyrimidine dimer DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site." [GOC:elh, PMID:9224623] xref: GO:0000704 is_a: CCO:F0000411 ! DNA-(apurinic or apyrimidinic site) lyase activity is_a: CCO:F0000917 ! endodeoxyribonuclease activity is_a: CCO:F0004051 ! DNA N-glycosylase activity [Term] id: CCO:F0000099 name: DNA strand annealing activity namespace: molecular_function def: "Facilitates the base-pairing of complementary single-stranded DNA." [GOC:elh] xref: GO:0000739 is_a: CCO:F0000282 ! double-stranded DNA binding is_a: CCO:F0000288 ! single-stranded DNA binding [Term] id: CCO:F0000100 name: mating pheromone activity namespace: molecular_function def: "The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted." [GOC:clt, GOC:elh] xref: GO:0000772 is_a: CCO:F0001483 ! pheromone activity [Term] id: CCO:F0000101 name: phosphatidyl-N-methylethanolamine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine." [EC:2.1.1.71] subset: gosubset_prok synonym: "methyltransferase II" RELATED [EC:2.1.1.71] synonym: "phosphatidyl-N-methylethanolamine methyltransferase activity" EXACT [EC:2.1.1.71] synonym: "phosphatidyl-N-monomethylethanolamine methyltransferase activity" EXACT [EC:2.1.1.71] synonym: "phosphatidylethanolamine methyltransferase I" RELATED [EC:2.1.1.71] synonym: "phosphatidylmonomethylethanolamine methyltransferase activity" EXACT [EC:2.1.1.71] synonym: "phospholipid methyltransferase activity" EXACT [EC:2.1.1.71] synonym: "PLMT" EXACT [] synonym: "S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.71] xref: EC:2.1.1.71 xref: GO:0000773 xref: MetaCyc:2.1.1.71-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0000102 name: adenyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins." [GOC:kd] subset: gosubset_prok xref: GO:0000774 is_a: CCO:F0004466 ! adenyl nucleotide binding [Term] id: CCO:F0000103 name: diacylglycerol pyrophosphate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: diacylglycerol pyrophosphate + H20 = 3-sn-phosphatidate + phosphate." [EC:3.6.1.-, PMID:8567632, PMID:9452443] synonym: "DGPP phosphatase activity" EXACT [] synonym: "DGPP phosphohydrolase activity" EXACT [] xref: GO:0000810 is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0000104 name: nicotinamide riboside kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nicotinamide riboside = ADP + nicotinamide nucleotide (NMN)." [PMID:15137942] xref: GO:0000816 is_a: CCO:F0004129 ! nucleoside kinase activity [Term] id: CCO:F0000105 name: inositol hexakisphosphate binding namespace: molecular_function def: "Interacting selectively with inositol hexakisphosphate." [GOC:go_curator] synonym: "InsP6 binding" EXACT [] synonym: "IP6 binding" EXACT [] xref: GO:0000822 is_a: CCO:F0005812 ! alcohol binding [Term] id: CCO:F0000106 name: inositol trisphosphate 6-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate." [GOC:elh] synonym: "ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity" EXACT [] synonym: "EC:2.7.1.151" BROAD [] synonym: "inositol polyphosphate multikinase activity" BROAD [] synonym: "IpmK" BROAD [] xref: GO:0000823 is_a: CCO:F0008191 ! inositol trisphosphate kinase activity [Term] id: CCO:F0000107 name: inositol tetrakisphosphate 3-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate." [GOC:elh] synonym: "1D-myo-inositol-tetrakisphosphate 3-kinase activity" EXACT [] synonym: "EC:2.7.1.151" BROAD [] synonym: "inositol 1,4,5,6-tetrakisphosphate 3-kinase activity" EXACT [] synonym: "inositol polyphosphate multikinase activity" BROAD [] synonym: "IpmK" BROAD [] xref: GO:0000824 is_a: CCO:F0008190 ! inositol tetrakisphosphate kinase activity [Term] id: CCO:F0000108 name: inositol tetrakisphosphate 6-kinase activity namespace: molecular_function def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP." [GOC:elh] synonym: "1D-myo-inositol-tetrakisphosphate 6-kinase activity" EXACT [] synonym: "inositol 1,3,4,5-tetrakisphosphate 6-kinase activity" EXACT [] xref: GO:0000825 is_a: CCO:F0008190 ! inositol tetrakisphosphate kinase activity [Term] id: CCO:F0000109 name: inositol pyrophosphate synthase activity namespace: molecular_function def: "Catalysis of the phosphorylation of inositol phosphates which possess pyrophosphate bonds." [GOC:elh, PMID:16429326] synonym: "inositol diphosphate synthase activity" EXACT [] xref: GO:0000826 is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0000110 name: inositol 1,3,4,5,6-pentakisphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown)." [GOC:elh, PMID:11311242] synonym: "EC:2.7.4.21" BROAD [] xref: GO:0000827 is_a: CCO:F0000109 ! inositol pyrophosphate synthase activity [Term] id: CCO:F0000111 name: inositol hexakisphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate (IP6) = ADP + diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5; isomer unknown)." [GOC:elh, PMID:16429326] xref: GO:0000828 is_a: CCO:F0000109 ! inositol pyrophosphate synthase activity [Term] id: CCO:F0000112 name: inositol heptakisphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5; isomer unknown) = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4; isomer unknown)." [GOC:elh, PMID:16429326] xref: GO:0000829 is_a: CCO:F0000109 ! inositol pyrophosphate synthase activity [Term] id: CCO:F0000113 name: inositol hexakisphosphate 4-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate." [GOC:elh, PMID:16429326] xref: GO:0000830 is_a: CCO:F0005070 ! inositol hexakisphosphate 4-kinase or 6-kinase activity [Term] id: CCO:F0000114 name: inositol hexakisphosphate 6-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate." [GOC:elh, PMID:16429326] xref: GO:0000831 is_a: CCO:F0005070 ! inositol hexakisphosphate 4-kinase or 6-kinase activity [Term] id: CCO:F0000115 name: inositol hexakisphosphate 5-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate." [GOC:elh, PMID:16429326] synonym: "ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity" EXACT [] synonym: "EC:2.7.4.21" BROAD [] xref: GO:0000832 is_a: CCO:F0000111 ! inositol hexakisphosphate kinase activity [Term] id: CCO:F0000116 name: inositol heptakisphosphate 4-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate." [GOC:elh, PMID:16429326] synonym: "diphosphoinositol-pentakisphosphate 4-kinase activity" EXACT [] synonym: "IP7 4-kinase activity" EXACT [] xref: GO:0000833 is_a: CCO:F0005076 ! inositol heptakisphosphate 4-kinase or 6-kinase activity [Term] id: CCO:F0000117 name: inositol heptakisphosphate 6-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate." [GOC:elh, PMID:16429326] xref: GO:0000834 is_a: CCO:F0005076 ! inositol heptakisphosphate 4-kinase or 6-kinase activity [Term] id: CCO:F0000118 name: translation repressor activity, nucleic acid binding namespace: molecular_function def: "Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding to nucleic acid." [GOC:clt] xref: GO:0000900 is_a: CCO:F0001739 ! translation factor activity, nucleic acid binding is_a: CCO:F0004416 ! translation repressor activity [Term] id: CCO:F0000119 name: translation repressor activity, non-nucleic acid binding namespace: molecular_function def: "Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid." [GOC:clt] xref: GO:0000901 is_a: CCO:F0004416 ! translation repressor activity is_a: CCO:F0006095 ! translation factor activity, non-nucleic acid binding [Term] id: CCO:F0000120 name: 6,7-dimethyl-8-ribityllumazine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxy-2-butanone 4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate." [EC:5.4.-.-, PMID:7559556] synonym: "lumazine synthase activity" BROAD [MetaCyc:LUMAZINESYN-CPLX] xref: EC:5.4.-.- xref: GO:0000906 is_a: CCO:F0003428 ! intramolecular transferase activity, transferring acyl groups [Term] id: CCO:F0000121 name: sulfonate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = SO3(2-) (sulfite) + aminoacetaldehyde + succinate + CO2." [EC:1.14.11.-, GOC:clt, PMID:10482536] subset: gosubset_prok synonym: "sulfonate/alpha-ketoglutarate dioxygenase activity" EXACT [] synonym: "sulphonate dioxygenase activity" EXACT [] xref: EC:1.14.11.- xref: GO:0000907 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0000122 name: taurine dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: taurine + 2-oxoglutarate + O2 = SO3(2-) (sulfite) + aminoacetaldehyde + succinate + CO2." [EC:1.14.11.17, MetaCyc:RXN0-299] subset: gosubset_prok synonym: "2-aminoethanesulfonate dioxygenase activity" EXACT [EC:1.14.11.17] synonym: "alpha-ketoglutarate-dependent taurine dioxygenase activity" EXACT [EC:1.14.11.17] synonym: "taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)" EXACT [EC:1.14.11.17] xref: EC:1.14.11.17 xref: GO:0000908 xref: MetaCyc:RXN0-299 is_a: CCO:F0000121 ! sulfonate dioxygenase activity [Term] id: CCO:F0000123 name: base pairing with rRNA namespace: molecular_function def: "Interacting selectively with ribosomal ribonucleic acid (rRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target rRNA molecule." [GOC:krc] comment: Note that with respect to annotation, "base pairing with RNA" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with other RNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. xref: GO:0000944 is_a: CCO:F0000091 ! base pairing with RNA is_a: CCO:F0004192 ! rRNA binding [Term] id: CCO:F0000124 name: base pairing with snRNA namespace: molecular_function def: "Interacting selectively with small nuclear ribonucleic acid (snRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target snRNA molecule." [GOC:krc] comment: Note that with respect to annotation, "base pairing with RNA" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with other RNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. xref: GO:0000945 is_a: CCO:F0000091 ! base pairing with RNA is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0000125 name: base pairing with tRNA namespace: molecular_function def: "Interacting selectively with transfer ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target tRNA molecule." [GOC:krc] comment: Note that with respect to annotation, "base pairing with RNA" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with other RNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function. xref: GO:0000946 is_a: CCO:F0000015 ! tRNA binding is_a: CCO:F0000091 ! base pairing with RNA [Term] id: CCO:F0000126 name: glycerophosphodiester transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol." [GOC:mcc, PMID:12912892] xref: GO:0001406 is_a: CCO:F0002968 ! organophosphate ester transmembrane transporter activity [Term] id: CCO:F0000127 name: guanine nucleotide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of the membrane to the other." [GOC:mcc] xref: GO:0001409 is_a: CCO:F0002687 ! purine nucleotide transmembrane transporter activity [Term] id: CCO:F0000128 name: legumain activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins and small-molecule substrates at Asn-Xaa bonds." [EC:3.4.22.34] synonym: "asparaginyl endopeptidase activity" RELATED [EC:3.4.22.34] synonym: "bean endopeptidase activity" RELATED [EC:3.4.22.34] synonym: "citvac" RELATED [EC:3.4.22.34] synonym: "hemoglobinase activity" RELATED [EC:3.4.22.34] synonym: "phaseolin activity" RELATED [EC:3.4.22.34] synonym: "proteinase B" RELATED [EC:3.4.22.34] synonym: "PRSC1 gene product (Homo sapiens)" RELATED [EC:3.4.22.34] synonym: "vicilin peptidohydrolase activity" RELATED [EC:3.4.22.34] xref: EC:3.4.22.34 xref: GO:0001509 xref: MetaCyc:3.4.22.34-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0000129 name: dihydronicotinamide riboside quinone reductase activity namespace: molecular_function def: "Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone." [EC:1.10.99.2] synonym: "1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase activity" EXACT [EC:1.10.99.2] synonym: "N-ribosyldihydronicotinamide dehydrogenase (quinone) activity" EXACT [EC:1.10.99.2] synonym: "NAD(P)H:quinone oxidoreductase 2 activity" EXACT [EC:1.10.99.2] synonym: "NAD(P)H:quinone oxidoreductase-2" RELATED [EC:1.10.99.2] synonym: "NAD(P)H:quinone oxidoreductase2" RELATED [EC:1.10.99.2] synonym: "NQO(2) activity" EXACT [EC:1.10.99.2] synonym: "NQO2" RELATED [EC:1.10.99.2] synonym: "NRH:quinone oxidoreductase 2 activity" NARROW [EC:1.10.99.2] synonym: "QR2 activity" RELATED [EC:1.10.99.2] synonym: "quinone reductase 2 activity" RELATED [EC:1.10.99.2] synonym: "ribosyldihydronicotinamide dehydrogenase (quinone) activity" EXACT [] xref: EC:1.10.99.2 xref: GO:0001512 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0000130 name: opioid peptide activity namespace: molecular_function def: "Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0001515 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0000131 name: N-acetylglucosamine 6-O-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate." [GOC:ai, GOC:hjd] synonym: "N-acetylglucosamine 6-O-sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0001517 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0000132 name: lipopolysaccharide binding namespace: molecular_function def: "Interacting selectively with lipopolysaccharide." [PMID:11079463] synonym: "endotoxin binding" BROAD [] synonym: "LPS binding" EXACT [] xref: GO:0001530 is_a: CCO:F0000239 ! pattern binding [Term] id: CCO:F0000133 name: interleukin-21 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-21 receptor." [GOC:ai] synonym: "IL-21" NARROW [] synonym: "interleukin-21 receptor ligand" NARROW [] xref: GO:0001531 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0000134 name: interleukin-21 receptor activity namespace: molecular_function def: "Combining with interleukin-21 to initiate a change in cell activity." [GOC:jl] synonym: "IL-21R" EXACT [] xref: GO:0001532 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004241 ! interleukin-21 binding [Term] id: CCO:F0000135 name: N-acetylgalactosamine 4-O-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate." [EC:2.8.2.-, GOC:ai] synonym: "N-acetylgalactosamine 4-O-sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0001537 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0000136 name: beta-amyloid binding namespace: molecular_function def: "Interacting selectively with beta-amyloid peptide/protein and/or its precursor." [GOC:hjd] xref: GO:0001540 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000137 name: phorbol ester receptor activity namespace: molecular_function def: "Combining with a phorbol ester to initiate a change in cell activity." [GOC:ai, PMID:10506570] xref: GO:0001565 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0000138 name: non-kinase phorbol ester receptor activity namespace: molecular_function def: "Phorbol ester/diacylglycerol binding proteins that do not have intrinsic kinase activity." [PMID:10506570] xref: GO:0001566 is_a: CCO:F0000137 ! phorbol ester receptor activity [Term] id: CCO:F0000139 name: cholesterol 25-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: cholesterol + AH2 + O2 = 25-hydroxycholesterol + A + H2O." [EC:1.14.99.38] synonym: "cholesterol 25-monooxygenase activity" EXACT [EC:1.14.99.38] synonym: "cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity" EXACT [EC:1.14.99.38] xref: EC:1.14.99.38 xref: GO:0001567 is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0000140 name: non-tyrosine kinase fibroblast growth factor receptor activity namespace: molecular_function def: "A receptor belonging to the FGFR family but lacking the tyrosine kinase domain." [PMID:11418238] synonym: "non-tyrosine kinase FGF receptor activity" EXACT [] synonym: "non-tyrosine kinase FGFR activity" EXACT [] xref: GO:0001571 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0000141 name: rhodopsin-like receptor activity namespace: molecular_function def: "A G-protein coupled receptor that is structurally/functionally related to the rhodopsin receptor." [GOC:dph, GOC:tb, IUPHAR_GPCR:1505] subset: gosubset_prok synonym: "Class A G protein coupled receptor" EXACT [] synonym: "Class A G-protein coupled receptor" EXACT [] synonym: "Class A GPCR" EXACT [] synonym: "class A orphan receptor activity" EXACT [] xref: GO:0001584 xref: GO:0001620 is_a: CCO:F0001272 ! G-protein coupled receptor activity [Term] id: CCO:F0000142 name: 5-HT1 receptor activity namespace: molecular_function xref: GO:0001586 is_a: CCO:F0001331 ! serotonin receptor activity [Term] id: CCO:F0000143 name: 5-HT2 receptor activity namespace: molecular_function xref: GO:0001587 is_a: CCO:F0001331 ! serotonin receptor activity [Term] id: CCO:F0000144 name: dopamine D1 receptor-like receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds the neurotransmitter dopamine and activates adenylate cyclase via coupling to Gs." [ISBN:0953351033] xref: GO:0001588 is_a: CCO:F0001294 ! dopamine receptor activity [Term] id: CCO:F0000145 name: dopamine D5 receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D5 receptors." [IUPHAR_RECEPTOR:2260] xref: GO:0001589 is_a: CCO:F0000144 ! dopamine D1 receptor-like receptor activity [Term] id: CCO:F0000146 name: dopamine D1 receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D1 receptors." [IUPHAR_RECEPTOR:2252] xref: GO:0001590 is_a: CCO:F0000144 ! dopamine D1 receptor-like receptor activity [Term] id: CCO:F0000147 name: dopamine D2 receptor-like receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds the neurotransmitter dopamine and inhibits adenylate cyclase via coupling to Gi/Go." [ISBN:0953351033] xref: GO:0001591 is_a: CCO:F0001294 ! dopamine receptor activity [Term] id: CCO:F0000148 name: dopamine D3 receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D3 receptors." [IUPHAR_RECEPTOR:2256] xref: GO:0001592 is_a: CCO:F0000147 ! dopamine D2 receptor-like receptor activity [Term] id: CCO:F0000149 name: dopamine D4 receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D4 receptors." [IUPHAR_RECEPTOR:2258] xref: GO:0001593 is_a: CCO:F0000147 ! dopamine D2 receptor-like receptor activity [Term] id: CCO:F0000150 name: trace-amine receptor activity namespace: molecular_function xref: GO:0001594 is_a: CCO:F0001782 ! amine receptor activity [Term] id: CCO:F0000151 name: angiotensin receptor activity namespace: molecular_function def: "Combining with angiotensin to initiate a change in cell activity." [GOC:ai] xref: GO:0001595 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000152 name: angiotensin type I receptor activity namespace: molecular_function xref: GO:0001596 is_a: CCO:F0000151 ! angiotensin receptor activity [Term] id: CCO:F0000153 name: chemokine receptor-like receptor activity namespace: molecular_function xref: GO:0001598 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000154 name: endothelin-A receptor activity namespace: molecular_function def: "A G-protein coupled receptor that preferentially binds endothelin 1." [IUPHAR_RECEPTOR:2263, PMID:8582288] xref: GO:0001599 is_a: CCO:F0001303 ! endothelin receptor activity [Term] id: CCO:F0000155 name: endothelin-B receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds all endothelin molecules with approximately equal affinity." [IUPHAR_RECEPTOR:2265, PMID:8582288] xref: GO:0001600 is_a: CCO:F0001303 ! endothelin receptor activity [Term] id: CCO:F0000156 name: peptide YY receptor activity namespace: molecular_function def: "Combining with gut peptide YY to initiate a change in cell activity." [PMID:9315606] xref: GO:0001601 is_a: CCO:F0001321 ! neuropeptide Y receptor activity [Term] id: CCO:F0000157 name: pancreatic polypeptide receptor activity namespace: molecular_function def: "Combining with pancreatic polypeptide PP to initiate a change in cell activity." [PMID:9315606] xref: GO:0001602 is_a: CCO:F0001321 ! neuropeptide Y receptor activity [Term] id: CCO:F0000158 name: vasopressin-like receptor activity namespace: molecular_function xref: GO:0001603 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000159 name: urotensin II receptor activity namespace: molecular_function xref: GO:0001604 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000160 name: adrenomedullin receptor activity namespace: molecular_function def: "Combining with adrenomedullin to initiate a change in cell activity." [GOC:ai] synonym: "G10D receptor" NARROW [] xref: GO:0001605 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000161 name: GPR37/endothelin B-like receptor activity namespace: molecular_function xref: GO:0001606 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000162 name: neuromedin U receptor activity namespace: molecular_function def: "Combining with neuromedin U to initiate a change in cell activity." [GOC:ai] synonym: "NMUR activity" EXACT [] xref: GO:0001607 is_a: CCO:F0001769 ! neuropeptide receptor activity is_a: CCO:F0005747 ! neuromedin U binding [Term] id: CCO:F0000163 name: nucleotide receptor activity, G-protein coupled namespace: molecular_function def: "A GPCR that binds a nucleotide or nucleotide derivative as its ligand." [GOC:dph, IUPHAR_GPCR:1294] synonym: "G protein coupled nucleotide receptor activity" EXACT [] synonym: "G-protein-coupled nucleotide receptor activity" EXACT [] synonym: "nucleotide receptor activity, G protein coupled" EXACT [] xref: GO:0001608 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000164 name: adenosine receptor activity, G-protein coupled namespace: molecular_function def: "Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity." [GOC:mah, PMID:9755289] synonym: "A1 adenosine receptor activity, G protein coupled" NARROW [] synonym: "A1 adenosine receptor activity, G-protein coupled" NARROW [] synonym: "A2A adenosine receptor activity, G protein coupled" NARROW [] synonym: "A2A adenosine receptor activity, G-protein coupled" NARROW [] synonym: "A2B adenosine receptor activity, G protein coupled" NARROW [] synonym: "A2B adenosine receptor activity, G-protein coupled" NARROW [] synonym: "A3 adenosine receptor activity, G protein coupled" NARROW [] synonym: "A3 adenosine receptor activity, G-protein coupled" NARROW [] synonym: "adenosine nucleotide receptor" BROAD [] synonym: "adenosine receptor activity, G protein coupled" EXACT [] synonym: "G protein coupled A1 adenosine receptor activity" NARROW [] synonym: "G protein coupled A2A adenosine receptor activity" NARROW [] synonym: "G protein coupled A2B adenosine receptor activity" NARROW [] synonym: "G protein coupled A3 adenosine receptor activity" NARROW [] synonym: "G protein coupled adenosine receptor activity" EXACT [] synonym: "G-protein-coupled A1 adenosine receptor activity" NARROW [] synonym: "G-protein-coupled A2A adenosine receptor activity" NARROW [] synonym: "G-protein-coupled A2B adenosine receptor activity" NARROW [] synonym: "G-protein-coupled A3 adenosine receptor activity" NARROW [] synonym: "G-protein-coupled adenosine receptor activity" EXACT [] xref: GO:0001609 xref: GO:0001610 xref: GO:0001611 xref: GO:0001612 xref: GO:0001613 xref: GO:0008501 is_a: CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled [Term] id: CCO:F0000165 name: purinergic nucleotide receptor activity namespace: molecular_function def: "Combining with a purine nucleotide to initiate a change in cell activity." [GOC:mah] synonym: "P2Y receptor" NARROW [] synonym: "purinoceptor" BROAD [] synonym: "purinoreceptor" BROAD [] xref: GO:0001614 is_a: CCO:F0003183 ! nucleotide receptor activity [Term] id: CCO:F0000166 name: thyrotropin releasing hormone and secretagogue-like receptors activity namespace: molecular_function xref: GO:0001615 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000167 name: growth hormone secretagogue receptor activity namespace: molecular_function xref: GO:0001616 is_a: CCO:F0000166 ! thyrotropin releasing hormone and secretagogue-like receptors activity [Term] id: CCO:F0000168 name: growth hormone secretagogue-like receptor activity namespace: molecular_function xref: GO:0001617 is_a: CCO:F0000166 ! thyrotropin releasing hormone and secretagogue-like receptors activity [Term] id: CCO:F0000169 name: viral receptor activity namespace: molecular_function def: "Combining with a virus component to initiate a change in cell activity." [GOC:dph] xref: GO:0001618 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0000170 name: lysosphingolipid and lysophosphatidic acid receptor activity namespace: molecular_function def: "Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity." [GOC:dph] xref: GO:0001619 is_a: CCO:F0000141 ! rhodopsin-like receptor activity is_a: CCO:F0006072 ! bioactive lipid receptor activity [Term] id: CCO:F0000171 name: platelet ADP receptor activity namespace: molecular_function synonym: "K101 receptor" NARROW [] xref: GO:0001621 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000172 name: super conserved receptor expressed in brain receptor activity namespace: molecular_function synonym: "SREB receptor" EXACT [] xref: GO:0001622 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000173 name: Mas proto-oncogene receptor activity namespace: molecular_function xref: GO:0001623 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000174 name: RDC1 receptor activity namespace: molecular_function xref: GO:0001624 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000175 name: Epstein-Barr Virus-induced receptor activity namespace: molecular_function synonym: "EBV-induced receptor" EXACT [] xref: GO:0001625 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000176 name: nociceptin/orphanin-FQ receptor activity namespace: molecular_function synonym: "ORPH receptor" EXACT [] xref: GO:0001626 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000177 name: leucine-rich G-protein receptor-like receptor activity namespace: molecular_function synonym: "leucine-rich G protein receptor-like receptor activity" EXACT [] synonym: "LGR-like receptor" EXACT [] xref: GO:0001627 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000178 name: gastropyloric receptor activity namespace: molecular_function synonym: "GPR receptor" EXACT [] xref: GO:0001628 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000179 name: G-protein receptor 45-like receptor activity namespace: molecular_function synonym: "G protein receptor 45-like receptor activity" EXACT [] synonym: "GPR45-like receptor" EXACT [] xref: GO:0001629 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000180 name: GP40-like receptor activity namespace: molecular_function xref: GO:0001630 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0000181 name: cysteinyl leukotriene receptor activity namespace: molecular_function def: "Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide moiety based on cysteine." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "CysLT receptor" EXACT [] xref: GO:0001631 is_a: CCO:F0001314 ! leukotriene receptor activity [Term] id: CCO:F0000182 name: leukotriene B4 receptor activity namespace: molecular_function def: "Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "BLT receptor" NARROW [] xref: GO:0001632 is_a: CCO:F0001314 ! leukotriene receptor activity [Term] id: CCO:F0000183 name: secretin-like receptor activity namespace: molecular_function def: "A G-protein coupled receptor that is structurally/functionally related to the secretin receptor." [IUPHAR_GPCR:1506] synonym: "class B G protein coupled receptor" EXACT [] synonym: "class B G-protein coupled receptor" EXACT [] synonym: "class B GPCR" EXACT [] synonym: "class B orphan receptor activity" EXACT [] xref: GO:0001633 xref: GO:0001638 is_a: CCO:F0001272 ! G-protein coupled receptor activity [Term] id: CCO:F0000184 name: pituitary adenylate cyclase activating protein receptor activity namespace: molecular_function synonym: "PACAP receptor" EXACT [] synonym: "pituitary adenylate cyclase activating polypeptide receptor" EXACT [] synonym: "pituitary adenylyl cyclase activating protein receptor activity" EXACT [] xref: GO:0001634 xref: GO:0016522 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0000185 name: calcitonin gene-related polypeptide receptor activity namespace: molecular_function synonym: "CGRP receptor" EXACT [] xref: GO:0001635 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0000186 name: corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity namespace: molecular_function xref: GO:0001636 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0000187 name: G-protein chemoattractant receptor activity namespace: molecular_function synonym: "G protein chemoattractant receptor activity" EXACT [] xref: GO:0001637 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000188 name: PLC activating metabotropic glutamate receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system." [PMID:9016303] synonym: "Group I metabotropic glutamate receptor" RELATED [] synonym: "group I metabotropic glutamate receptor activity" RELATED [] synonym: "phospholipase C activating metabotropic glutamate receptor activity" EXACT [] xref: GO:0001639 is_a: CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity [Term] id: CCO:F0000189 name: adenylate cyclase inhibiting metabotropic glutamate receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds glutamate and inhibits adenylate cyclase activity." [GOC:dph] synonym: "adenylyl cyclase inhibiting metabotropic glutamate receptor activity" EXACT [] xref: GO:0001640 is_a: CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity [Term] id: CCO:F0000190 name: group II metabotropic glutamate receptor activity namespace: molecular_function def: "A G-protein coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity." [GOC:dph] xref: GO:0001641 is_a: CCO:F0000189 ! adenylate cyclase inhibiting metabotropic glutamate receptor activity [Term] id: CCO:F0000191 name: group III metabotropic glutamate receptor activity namespace: molecular_function def: "A G-protein coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity." [PMID:9016303] xref: GO:0001642 is_a: CCO:F0000189 ! adenylate cyclase inhibiting metabotropic glutamate receptor activity [Term] id: CCO:F0000192 name: cAMP receptor activity namespace: molecular_function def: "Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) to initiate a change in cell activity." [GOC:pg] synonym: "3',5' cAMP receptor activity" EXACT [] synonym: "3',5'-cAMP receptor activity" EXACT [] synonym: "adenosine 3',5'-cyclophosphate receptor activity" EXACT [] synonym: "class E G protein coupled receptor" BROAD [] synonym: "class E G-protein coupled receptor" BROAD [] synonym: "class E GPCR" BROAD [] synonym: "cyclic AMP receptor activity" EXACT [] xref: GO:0001644 xref: GO:0001646 is_a: CCO:F0003183 ! nucleotide receptor activity is_a: CCO:F0004464 ! cAMP binding [Term] id: CCO:F0000193 name: G-protein coupled cytokinin receptor activity namespace: molecular_function def: "Combining with a cytokinin to initiate a change in cell activity. The receptor is G-protein coupled." [GOC:dph] synonym: "G protein coupled cytokinin receptor activity" EXACT [] synonym: "G-protein-coupled cytokinin receptor activity" EXACT [] xref: GO:0001647 is_a: CCO:F0001272 ! G-protein coupled receptor activity is_a: CCO:F0002413 ! cytokinin receptor activity [Term] id: CCO:F0000194 name: proteinase activated receptor activity namespace: molecular_function xref: GO:0001648 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0000195 name: peptide receptor activity namespace: molecular_function def: "Combining with an extracellular or intracellular peptide to initiate a change in cell activity." [GOC:jl] synonym: "endogenous peptide receptor activity" NARROW [] synonym: "exogenous peptide receptor activity" NARROW [] xref: GO:0001653 is_a: CCO:F0001226 ! receptor activity is_a: CCO:F0005639 ! peptide binding [Term] id: CCO:F0000196 name: G-protein-coupled receptor binding namespace: molecular_function def: "Interacting selectively with a G-protein-coupled receptor." [GOC:ceb, GOC:dph] synonym: "G protein coupled receptor binding" EXACT [] synonym: "G protein coupled receptor ligand" NARROW [] synonym: "G-protein-coupled receptor ligand" NARROW [] xref: GO:0001664 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0000197 name: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein." [EC:2.4.99.3] synonym: "CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.3] synonym: "GalNAc alpha-2,6-sialyltransferase I activity" EXACT [EC:2.4.99.3] xref: EC:2.4.99.3 xref: GO:0001665 xref: MetaCyc:2.4.99.3-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0000198 name: phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate." [EC:3.1.3.36] synonym: "inositol 1,4,5-triphosphate 5-phosphomonoesterase activity" EXACT [EC:3.1.3.36] synonym: "phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase activity" EXACT [EC:3.1.3.36] synonym: "phosphatidylinositol 4,5-bisphosphate phosphatase activity" BROAD [EC:3.1.3.36] synonym: "phosphatidylinositol-bisphosphatase activity" BROAD [EC:3.1.3.36] synonym: "PtdIns(4,5)P(2) phosphatase activity" EXACT [EC:3.1.3.36] synonym: "PtdIns(4,5)P2 phosphatase activity" EXACT [EC:3.1.3.36] synonym: "triphosphoinositide phosphatase activity" BROAD [EC:3.1.3.36] synonym: "triphosphoinositide phosphomonoesterase activity" BROAD [EC:3.1.3.36] xref: EC:3.1.3.36 xref: GO:0001668 xref: GO:0004439 xref: MetaCyc:PHOSPHATIDYLINOSITOL-BISPHOSPHATASE-RXN is_a: CCO:F0000843 ! phosphoinositide 5-phosphatase activity is_a: CCO:F0005684 ! lipid phosphatase activity is_a: CCO:F0008466 ! phosphatidylinositol bisphosphate phosphatase activity [Term] id: CCO:F0000199 name: dopamine D2 receptor activity namespace: molecular_function def: "A G-protein coupled receptor that binds dopamine and has the pharmacological characteristics of classic D2 receptors." [IUPHAR_RECEPTOR:2254] xref: GO:0001670 is_a: CCO:F0000147 ! dopamine D2 receptor-like receptor activity [Term] id: CCO:F0000200 name: ATPase activator activity namespace: molecular_function def: "Functions to increase the rate of ATP hydrolysis." [GOC:ajp] synonym: "ATPase stimulator activity" EXACT [] xref: GO:0001671 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0000201 name: sialate O-acetylesterase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate." [EC:3.1.1.53, PMID:1991039] subset: gosubset_prok synonym: "N-acetylneuraminate acetyltransferase activity" EXACT [EC:3.1.1.53] synonym: "N-acyl-O-acetylneuraminate O-acetylhydrolase activity" EXACT [EC:3.1.1.53] synonym: "sialate 9(4)-O-acetylesterase activity" EXACT [] xref: EC:3.1.1.53 xref: GO:0001681 xref: MetaCyc:SIALATE-O-ACETYLESTERASE-RXN is_a: CCO:F0001731 ! acetylesterase activity [Term] id: CCO:F0000202 name: pseudophosphatase activity namespace: molecular_function def: "Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues." [GOC:ajp] xref: GO:0001691 is_a: CCO:F0004135 ! phosphatase inhibitor activity [Term] id: CCO:F0000203 name: L-amino-acid oxidase activity namespace: molecular_function def: "Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + H2O2." [EC:1.4.3.2] subset: gosubset_prok synonym: "L-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.2] synonym: "ophio-amino-acid oxidase activity" EXACT [EC:1.4.3.2] xref: EC:1.4.3.2 xref: GO:0001716 xref: MetaCyc:L-AMINO-ACID-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0000204 name: lipid kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of a simple or complex lipid." [GOC:hjd] subset: gosubset_prok xref: GO:0001727 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0000205 name: ceramide kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + ceramide = ADP + ceramide 1-phosphate." [EC:2.7.1.138] synonym: "acylsphingosine kinase activity" EXACT [EC:2.7.1.138] synonym: "ATP:ceramide 1-phosphotransferase activity" EXACT [EC:2.7.1.138] xref: EC:2.7.1.138 xref: GO:0001729 xref: MetaCyc:CERAMIDE-KINASE-RXN is_a: CCO:F0000204 ! lipid kinase activity [Term] id: CCO:F0000206 name: 2'-5'-oligoadenylate synthetase activity namespace: molecular_function def: "Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. Requires binding of double-stranded RNA." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "(2-5')oligo(A) synthetase activity" EXACT [] synonym: "2'-5' oligoadenylate synthetase activity" EXACT [] synonym: "2-5A synthetase activity" EXACT [] synonym: "oligo-2',5'-adenylate synthetase activity" EXACT [] xref: GO:0001730 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000207 name: galactosylceramide sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate." [EC:2.8.2.11, PMID:10727929] synonym: "3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity" EXACT [EC:2.8.2.11] synonym: "3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity" EXACT [EC:2.8.2.11] synonym: "cerebroside sulfotransferase activity" EXACT [] synonym: "galactocerebroside sulfotransferase activity" EXACT [EC:2.8.2.11] synonym: "galactolipid sulfotransferase activity" EXACT [EC:2.8.2.11] synonym: "galactosylceramide sulphotransferase activity" EXACT [] synonym: "glycolipid sulfotransferase activity" EXACT [EC:2.8.2.11] synonym: "glycosphingolipid sulfotransferase activity" EXACT [EC:2.8.2.11] synonym: "GSase" EXACT [EC:2.8.2.11] xref: EC:2.8.2.11 xref: GO:0001733 xref: MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN is_a: CCO:F0007995 ! galactose 3-O-sulfotransferase activity [Term] id: CCO:F0000208 name: mRNA (N6-adenosine)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R = purine, and H = C, A, or U." [GOC:hjd] xref: GO:0001734 xref: Reactome:2399 is_a: CCO:F0001761 ! mRNA methyltransferase activity [Term] id: CCO:F0000209 name: prenylcysteine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H20 = a prenal + L-cysteine + H202." [GOC:hjd] synonym: "prenylcysteine lyase activity" EXACT [EC:1.8.3.5] synonym: "S-prenyl-L-cysteine:oxygen oxidoreductase activity" EXACT [EC:1.8.3.5] xref: EC:1.8.3.5 xref: GO:0001735 xref: MetaCyc:1.8.3.5-RXN is_a: CCO:F0003263 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor [Term] id: CCO:F0000210 name: retinal dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal." [EC:1.2.1.36] synonym: "cytosolic retinal dehydrogenase activity" EXACT [EC:1.2.1.36] synonym: "retinal:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.36] xref: EC:1.2.1.36 xref: GO:0001758 xref: MetaCyc:RETINAL-DEHYDROGENASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000211 name: aminocarboxymuconate-semialdehyde decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-amino-3-(3-oxoprop-2-enyl)-but-2-enedioate = 2-aminomuconate semialdehyde + CO2." [EC:4.1.1.45] subset: gosubset_prok synonym: "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)" EXACT [EC:4.1.1.45] synonym: "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity" EXACT [EC:4.1.1.45] synonym: "2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity" EXACT [EC:4.1.1.45] synonym: "alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity" EXACT [EC:4.1.1.45] synonym: "alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity" EXACT [EC:4.1.1.45] synonym: "picolinic acid carboxylase activity" EXACT [EC:4.1.1.45] synonym: "picolinic acid decarboxylase activity" EXACT [EC:4.1.1.45] xref: EC:4.1.1.45 xref: GO:0001760 xref: MetaCyc:4.1.1.45-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000212 name: beta-alanine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid." [GOC:hjd] synonym: "beta-alanine transporter activity" BROAD [] xref: GO:0001761 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity [Term] id: CCO:F0000213 name: phosphotyrosine binding namespace: molecular_function def: "Interacting selectively with a phosphorylated tyrosine residue within a protein." [PMID:14636584] xref: GO:0001784 is_a: CCO:F0006109 ! protein phosphorylated amino acid binding [Term] id: CCO:F0000214 name: prostaglandin J receptor activity namespace: molecular_function def: "Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity." [PMID:12878180] synonym: "PGJ receptor activity" RELATED [] synonym: "PGJ(2) receptor activity" EXACT [] xref: GO:0001785 is_a: CCO:F0001297 ! prostaglandin receptor activity [Term] id: CCO:F0000215 name: phosphatidylserine binding namespace: molecular_function def: "Interacting selectively with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:12000961] xref: GO:0001786 is_a: CCO:F0001666 ! phospholipid binding [Term] id: CCO:F0000216 name: polymeric immunoglobulin binding namespace: molecular_function def: "Interacting selectively with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001790 is_a: CCO:F0004198 ! immunoglobulin binding [Term] id: CCO:F0000217 name: IgM binding namespace: molecular_function def: "Interacting selectively with an immunoglobulin of the IgM isotype." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001791 is_a: CCO:F0004198 ! immunoglobulin binding [Term] id: CCO:F0000218 name: polymeric immunoglobulin receptor activity namespace: molecular_function def: "Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001792 is_a: CCO:F0000216 ! polymeric immunoglobulin binding is_a: CCO:F0004150 ! immunoglobulin receptor activity [Term] id: CCO:F0000219 name: IgM receptor activity namespace: molecular_function def: "Combining with an immunoglobulin of the IgM isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001793 is_a: CCO:F0000217 ! IgM binding is_a: CCO:F0004150 ! immunoglobulin receptor activity [Term] id: CCO:F0000220 name: opsonin binding namespace: molecular_function def: "Interacting selectively with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that an opsonin is a blood serum protein or fragment which when deposited on the surface of a bacteria, virus, immune complex, or other particulate material acts a signal for phagocytosis to cells bearing the appropriate receptors. Not all complement components or fragments and not all antibodies have opsonic properties. xref: GO:0001846 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000221 name: opsonin receptor activity namespace: molecular_function def: "Combining with an opsonin to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001847 is_a: CCO:F0000220 ! opsonin binding is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0000222 name: complement binding namespace: molecular_function def: "Interacting selectively with any component or product of the complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways. xref: GO:0001848 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000223 name: complement component C1q binding namespace: molecular_function def: "Interacting selectively with the C1q component of the classical complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001849 is_a: CCO:F0000220 ! opsonin binding is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000224 name: complement component C3a binding namespace: molecular_function def: "Interacting selectively with the C3a product of the complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001850 is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000225 name: complement component C3b binding namespace: molecular_function def: "Interacting selectively with the C3b product of the complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001851 is_a: CCO:F0000220 ! opsonin binding is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000226 name: complement component iC3b binding namespace: molecular_function def: "Interacting selectively with the iC3b product of the complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001852 is_a: CCO:F0000220 ! opsonin binding is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000227 name: complement component C3dg binding namespace: molecular_function def: "Interacting selectively with the C3dg product of the complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001853 is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000228 name: complement component C3d binding namespace: molecular_function def: "Interacting selectively with the C3d product of the complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001854 is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000229 name: complement component C4b binding namespace: molecular_function def: "Interacting selectively with the C4b product of the classical complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001855 is_a: CCO:F0000220 ! opsonin binding is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000230 name: complement component C5a binding namespace: molecular_function def: "Interacting selectively with the C5a product of the complement cascade." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001856 is_a: CCO:F0000222 ! complement binding [Term] id: CCO:F0000231 name: complement component C1q receptor activity namespace: molecular_function def: "Combining with the C1q component of the classical complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001857 is_a: CCO:F0000221 ! opsonin receptor activity is_a: CCO:F0000223 ! complement component C1q binding is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0000232 name: complement component iC3b receptor activity namespace: molecular_function def: "Combining with the iC3b product of the complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001858 is_a: CCO:F0000221 ! opsonin receptor activity is_a: CCO:F0000226 ! complement component iC3b binding is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0000233 name: complement component C3dg receptor activity namespace: molecular_function def: "Combining with the C3dg product of the complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001859 is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0000234 name: complement component C3d receptor activity namespace: molecular_function def: "Combining with the C3d product of the complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001860 is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0000235 name: complement component C4b receptor activity namespace: molecular_function def: "Combining with the C4b product of the classical complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001861 is_a: CCO:F0000221 ! opsonin receptor activity is_a: CCO:F0000229 ! complement component C4b binding is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0000236 name: collectin binding namespace: molecular_function def: "Interacting selectively with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that collectins include such proteins as mannose-binding lectins (MBL) and surfactant proteins A and D (SP-A and SP-D). xref: GO:0001862 is_a: CCO:F0000220 ! opsonin binding [Term] id: CCO:F0000237 name: collectin receptor activity namespace: molecular_function def: "Combining with a collectin to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that collectins include such proteins as mannose-binding lectin (MBL) and surfactant proteins A and D (SP-A and SP-D). xref: GO:0001863 is_a: CCO:F0000221 ! opsonin receptor activity [Term] id: CCO:F0000238 name: pentraxin binding namespace: molecular_function def: "Interacting selectively with a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP). xref: GO:0001864 is_a: CCO:F0000220 ! opsonin binding [Term] id: CCO:F0000239 name: pattern binding namespace: molecular_function def: "Interacting selectively with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan." [PMID:12072369, PMID:12225919, PMID:12507420, PMID:12925128, PMID:14523544] comment: Note that this term and its child terms are intended for annotation of gene products which function to recognize (bind) the repeating structural units such as polysaccharides or peptidoglycans commonly found in microbial cell walls and virions. If such binding is coupled to signal transduction, use 'pattern recognition receptor activity ; GO:0008329' instead. subset: goslim_pir subset: gosubset_prok synonym: "pattern recognition activity" BROAD [] xref: GO:0001871 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000240 name: zymosan binding namespace: molecular_function def: "Interacting selectively with zymosan." [PMID:14707091] xref: GO:0001872 is_a: CCO:F0004357 ! polysaccharide binding [Term] id: CCO:F0000241 name: polysaccharide receptor activity namespace: molecular_function def: "Combining with a polysaccharide to initiate a change in cell activity." [PMID:14707091] xref: GO:0001873 is_a: CCO:F0001838 ! pattern recognition receptor activity is_a: CCO:F0004357 ! polysaccharide binding [Term] id: CCO:F0000242 name: zymosan receptor activity namespace: molecular_function def: "Combining with zymosan to initiate a change in cell activity." [PMID:14707091] xref: GO:0001874 is_a: CCO:F0000240 ! zymosan binding is_a: CCO:F0000241 ! polysaccharide receptor activity [Term] id: CCO:F0000243 name: lipopolysaccharide receptor activity namespace: molecular_function def: "Combining with lipopolysaccharide to initiate a change in cell activity." [PMID:14609719] synonym: "endotoxin receptor activity" BROAD [] synonym: "LPS receptor activity" EXACT [] xref: GO:0001875 is_a: CCO:F0000132 ! lipopolysaccharide binding is_a: CCO:F0001838 ! pattern recognition receptor activity [Term] id: CCO:F0000244 name: lipoarabinomannan binding namespace: molecular_function def: "Interacting selectively with lipoarabinomannan." [PMID:10586073] synonym: "LAM binding" EXACT [] xref: GO:0001876 is_a: CCO:F0000239 ! pattern binding [Term] id: CCO:F0000245 name: lipoarabinomannan receptor activity namespace: molecular_function def: "Combining with lipoarabinomannan to initiate a change in cell activity." [PMID:10586073] synonym: "LAM receptor activity" EXACT [] xref: GO:0001877 is_a: CCO:F0000244 ! lipoarabinomannan binding is_a: CCO:F0001838 ! pattern recognition receptor activity [Term] id: CCO:F0000246 name: nucleoside binding namespace: molecular_function def: "Interacting selectively with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose." [GOC:hjd] subset: goslim_pir subset: gosubset_prok xref: GO:0001882 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000247 name: purine nucleoside binding namespace: molecular_function def: "Interacting selectively with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose." [GOC:hjd] xref: GO:0001883 is_a: CCO:F0000246 ! nucleoside binding [Term] id: CCO:F0000248 name: pyrimidine nucleoside binding namespace: molecular_function def: "Interacting selectively with a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose." [GOC:hjd] xref: GO:0001884 is_a: CCO:F0000246 ! nucleoside binding [Term] id: CCO:F0000249 name: glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan." [EC:2.4.1.223] synonym: "alpha-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.223] synonym: "alpha-N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.223] synonym: "alpha1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.223] synonym: "glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.223] synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.223] xref: EC:2.4.1.223 xref: GO:0001888 is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0000250 name: farnesylated protein binding namespace: molecular_function def: "Interacting selectively with a farnesylated protein." [GOC:add, PMID:14555765] xref: GO:0001918 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000251 name: glycoprotein binding namespace: molecular_function def: "Interacting selectively with a glycoprotein, a protein that contains covalently bound glycose (monosaccharide) residues. These also include proteoglycans." [GOC:hjd, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0001948 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000252 name: alpha-1,3-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,3-linkage." [GOC:hjd, PMID:10854427] synonym: "isoglobotriaosylceramide synthase" NARROW [] xref: EC:2.4.1.- xref: GO:0001962 is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0000253 name: G-protein alpha-subunit binding namespace: molecular_function def: "Interacting selectively with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide." [GOC:hjd] synonym: "G-alpha protein subunit binding" EXACT [] xref: GO:0001965 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000254 name: fibronectin binding namespace: molecular_function def: "Interacting selectively with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids." [GOC:hjd] xref: GO:0001968 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000255 name: retinoic acid binding namespace: molecular_function def: "Interacting selectively with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid." [GOC:hjd] xref: GO:0001972 is_a: CCO:F0001639 ! retinoid binding [Term] id: CCO:F0000256 name: protease binding namespace: molecular_function def: "Interacting selectively with any protease or peptidase." [GOC:hjd] xref: GO:0002020 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0000257 name: p53 binding namespace: molecular_function def: "Interacting selectively with one of the p53 family of proteins." [GOC:hjd] xref: GO:0002039 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000258 name: opsin binding namespace: molecular_function def: "Interacting selectively with an opsin, any of a group of hydrophbic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception." [GOC:hjd] xref: GO:0002046 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0000259 name: nucleobase binding namespace: molecular_function def: "Interacting selectively with an nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases." [GOC:hjd] subset: goslim_pir subset: gosubset_prok xref: GO:0002054 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000260 name: adenine binding namespace: molecular_function def: "Interacting selectively with adenine, a purine base." [GOC:hjd] synonym: "6-aminopurine binding" EXACT [] xref: GO:0002055 is_a: CCO:F0000265 ! purine binding [Term] id: CCO:F0000261 name: cytosine binding namespace: molecular_function def: "Interactiing selectively with cytosine." [GOC:hjd] xref: GO:0002056 is_a: CCO:F0000266 ! pyrimidine binding [Term] id: CCO:F0000262 name: guanine binding namespace: molecular_function def: "Interacting selectively with guanine." [GOC:hjd] xref: GO:0002057 is_a: CCO:F0000265 ! purine binding [Term] id: CCO:F0000263 name: uracil binding namespace: molecular_function def: "Interacting selectively with uracil." [GOC:hjd] xref: GO:0002058 is_a: CCO:F0000266 ! pyrimidine binding [Term] id: CCO:F0000264 name: thymine binding namespace: molecular_function def: "Interacting selectively with thymine." [GOC:hjd] xref: GO:0002059 is_a: CCO:F0000266 ! pyrimidine binding [Term] id: CCO:F0000265 name: purine binding namespace: molecular_function def: "Interacting selectively with a purine, an organic nitrogenous base." [GOC:hjd] xref: GO:0002060 is_a: CCO:F0000259 ! nucleobase binding [Term] id: CCO:F0000266 name: pyrimidine binding namespace: molecular_function def: "Interacting selectively with a pyrimidine, an organic nitrogenous base." [GOC:hjd] synonym: "1,3-diazine binding" EXACT [] xref: GO:0002061 is_a: CCO:F0000259 ! nucleobase binding [Term] id: CCO:F0000267 name: 4-hydroxybenzoate decaprenyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: decaprenyl-PP + p-hydroxybenzoate = decaprenyl-4-hydroxybenzoate + diphosphate." [GOC:hjd] xref: GO:0002083 is_a: CCO:F0000268 ! polyprenyltransferase activity [Term] id: CCO:F0000268 name: polyprenyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor)." [GOC:hjd] subset: gosubset_prok xref: GO:0002094 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0000269 name: interleukin-33 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-33 receptor." [GOC:hjd] xref: GO:0002112 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0000270 name: interleukin-33 binding namespace: molecular_function def: "Interacting selectively with interleukin-33." [GOC:hjd] xref: GO:0002113 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0000271 name: interleukin-33 receptor activity namespace: molecular_function def: "Combining with interleukin-33 to initiate a change in cell activity." [GOC:hjd] xref: GO:0002114 is_a: CCO:F0000270 ! interleukin-33 binding is_a: CCO:F0001254 ! interleukin receptor activity [Term] id: CCO:F0000272 name: molecular_function namespace: molecular_function def: "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GOC:go_curators] comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. Note that when this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this. subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "molecular function unknown" NARROW [] xref: GO:0003674 xref: GO:0005554 is_a: CCO:U0000001 ! biological continuant [Term] id: CCO:F0000273 name: nucleic acid binding namespace: molecular_function def: "Interacting selectively with any nucleic acid." [GOC:jl] subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: gosubset_prok xref: GO:0003676 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000274 name: DNA binding namespace: molecular_function def: "Interacting selectively with DNA (deoxyribonucleic acid)." [GOC:jl] subset: goslim_candida subset: goslim_generic subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "microtubule/chromatin interaction" RELATED [] synonym: "plasmid binding" NARROW [] xref: GO:0003677 is_a: CCO:F0000273 ! nucleic acid binding [Term] id: CCO:F0000275 name: DNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of a DNA duplex." [GOC:jl, GOC:mah, http://cancerweb.ncl.ac.uk/] comment: Consider also annotating to the molecular function term 'DNA binding ; GO:0003677'. subset: gosubset_prok xref: GO:0003678 xref: GO:0003679 is_a: CCO:F0000803 ! helicase activity [Term] id: CCO:F0000276 name: AT DNA binding namespace: molecular_function def: "Interacting selectively with oligo(A) and oligo(T) tracts of DNA (AT DNA)." [GOC:jl, UniProtKB:P13483] synonym: "AT binding" EXACT [] xref: GO:0003680 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0000277 name: bent DNA binding namespace: molecular_function def: "Interacting selectively with DNA in a bent conformation." [GOC:jl, PMID:12627977] subset: gosubset_prok xref: GO:0003681 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0000278 name: chromatin binding namespace: molecular_function def: "Interacting selectively with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_pir subset: goslim_plant synonym: "lamin/chromatin binding" BROAD [] synonym: "microtubule/chromatin interaction" RELATED [] synonym: "nuclear membrane vesicle binding to chromatin" NARROW [] xref: GO:0003682 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000279 name: damaged DNA binding namespace: molecular_function def: "Interacting selectively with damaged DNA." [GOC:jl] subset: gosubset_prok synonym: "DNA repair enzyme" RELATED [] synonym: "DNA repair protein" RELATED [] xref: GO:0003684 xref: Reactome:7372 is_a: CCO:F0000274 ! DNA binding [Term] id: CCO:F0000280 name: DNA replication origin binding namespace: molecular_function def: "Interacting selectively with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "ARS binding" NARROW [] xref: GO:0003688 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0000281 name: DNA clamp loader activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex." [GOC:mah, GOC:vw, PMID:16082778] subset: gosubset_prok synonym: "DNA clamp loading ATPase activity" EXACT [] synonym: "PCNA loading activity" NARROW [] synonym: "PCNA loading complex activity" NARROW [] xref: GO:0003689 xref: Reactome:9823 is_a: CCO:F0000274 ! DNA binding is_a: CCO:F0005069 ! DNA-protein loading ATPase activity [Term] id: CCO:F0000282 name: double-stranded DNA binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA." [GOC:elh] subset: gosubset_prok xref: GO:0003690 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0000283 name: double-stranded telomeric DNA binding namespace: molecular_function def: "Interacting selectively with double-stranded telomere-associated DNA." [GOC:jl, ISBN:0321000382] xref: GO:0003691 is_a: CCO:F0000282 ! double-stranded DNA binding is_a: CCO:F0005630 ! telomeric DNA binding [Term] id: CCO:F0000284 name: left-handed Z-DNA binding namespace: molecular_function def: "Interacting selectively with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags." [ISBN:0716720094] xref: GO:0003692 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0000285 name: P-element binding namespace: molecular_function def: "Interacting selectively with any P-element, a class of Drosophila transposon responsible for hybrid dysgenesis." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0003693 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0000286 name: random coil DNA binding namespace: molecular_function def: "Interacting selectively with DNA in a random coil configuration." [GOC:mah] synonym: "random coil binding" EXACT [] xref: GO:0003695 xref: GO:0016017 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0000287 name: satellite DNA binding namespace: molecular_function def: "Interacting selectively with satellite DNA, DNA containing highly repetitive sequences which makes up a large proportion of the eukaryotic genome." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0003696 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0000288 name: single-stranded DNA binding namespace: molecular_function def: "Interacting selectively with single-stranded DNA." [GOC:elh] subset: gosubset_prok xref: GO:0003697 xref: GO:0003698 xref: GO:0003699 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0000289 name: transcription factor activity namespace: molecular_function def: "The function of binding to a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex." [GOC:curators] subset: goslim_generic subset: goslim_plant subset: gosubset_prok xref: GO:0000130 xref: GO:0003700 is_a: CCO:F0000274 ! DNA binding is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000290 name: RNA polymerase I transcription factor activity namespace: molecular_function def: "Functions to initiate or regulate RNA polymerase I transcription." [GOC:jl] xref: GO:0003701 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000291 name: RNA polymerase II transcription factor activity namespace: molecular_function def: "Functions to initiate or regulate RNA polymerase II transcription." [GOC:jl] xref: GO:0003702 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000292 name: specific RNA polymerase II transcription factor activity namespace: molecular_function def: "Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II." [GOC:ma] xref: GO:0003704 is_a: CCO:F0000291 ! RNA polymerase II transcription factor activity [Term] id: CCO:F0000293 name: RNA polymerase II transcription factor activity, enhancer binding namespace: molecular_function def: "Functions to initiate or regulate RNA polymerase II transcription by binding an enhancer region of DNA." [GOC:jl] xref: GO:0003705 is_a: CCO:F0000289 ! transcription factor activity is_a: CCO:F0000291 ! RNA polymerase II transcription factor activity [Term] id: CCO:F0000294 name: ligand-regulated transcription factor activity namespace: molecular_function xref: GO:0003706 is_a: CCO:F0000292 ! specific RNA polymerase II transcription factor activity [Term] id: CCO:F0000295 name: steroid hormone receptor activity namespace: molecular_function def: "Combining with a steroid hormone to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0003707 is_a: CCO:F0001233 ! ligand-dependent nuclear receptor activity [Term] id: CCO:F0000296 name: retinoic acid receptor activity namespace: molecular_function def: "Combining with retinoic acid to initiate a change in cell activity. Retinoic acid is one of the forms of vitamin A." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. synonym: "vitamin A receptor activity" BROAD [] xref: GO:0003708 is_a: CCO:F0001233 ! ligand-dependent nuclear receptor activity [Term] id: CCO:F0000297 name: RNA polymerase III transcription factor activity namespace: molecular_function def: "Functions to initiate or regulate RNA polymerase III transcription." [GOC:jl] xref: GO:0003709 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000298 name: transcription elongation regulator activity namespace: molecular_function def: "Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation." [GOC:mah] subset: gosubset_prok synonym: "transcription elongation factor activity" EXACT [] synonym: "transcriptional elongation regulator activity" EXACT [] xref: GO:0003711 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000299 name: transcription cofactor activity namespace: molecular_function def: "The function that links a sequence-specific transcription factor to the core RNA polymerase II complex but does not bind DNA itself." [PMID:10213677] subset: gosubset_prok synonym: "transcriptional co-regulator" EXACT [] synonym: "transcriptional cofactor activity" EXACT [] xref: GO:0003712 is_a: CCO:F0001738 ! transcription factor binding is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000300 name: transcription coactivator activity namespace: molecular_function def: "The function of a transcription cofactor that activates transcription from a RNA polymerase II promoter; does not bind DNA itself." [GOC:ma] subset: gosubset_prok synonym: "transcription co-activator activity" EXACT [] xref: GO:0003713 is_a: CCO:F0000299 ! transcription cofactor activity is_a: CCO:F0003205 ! transcription activator activity [Term] id: CCO:F0000301 name: transcription corepressor activity namespace: molecular_function def: "The function of a transcription cofactor that represses transcription from a RNA polymerase II promoter; does not bind DNA itself." [GOC:ma] synonym: "transcription co-repressor activity" EXACT [] xref: GO:0003714 is_a: CCO:F0000299 ! transcription cofactor activity is_a: CCO:F0003206 ! transcription repressor activity [Term] id: CCO:F0000302 name: transcription termination factor activity namespace: molecular_function def: "Any activity that brings about termination of transcription." [GOC:mah] subset: gosubset_prok synonym: "transcriptional termination factor activity" EXACT [] xref: GO:0003715 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0000303 name: RNA polymerase I transcription termination factor activity namespace: molecular_function def: "Any activity that brings about termination of transcription by RNA polymerase I." [GOC:mah] synonym: "Pol I transcription termination factor activity" EXACT [] xref: GO:0003716 is_a: CCO:F0000302 ! transcription termination factor activity [Term] id: CCO:F0000304 name: RNA polymerase II transcription termination factor activity namespace: molecular_function def: "Any activity that brings about termination of transcription by RNA polymerase II." [GOC:mah] synonym: "Pol II transcription termination factor activity" EXACT [] xref: GO:0003717 is_a: CCO:F0000302 ! transcription termination factor activity [Term] id: CCO:F0000305 name: RNA polymerase III transcription termination factor activity namespace: molecular_function def: "Any activity that brings about termination of transcription by RNA polymerase III." [GOC:mah] synonym: "Pol III transcription termination factor activity" EXACT [] xref: GO:0003718 is_a: CCO:F0000302 ! transcription termination factor activity [Term] id: CCO:F0000306 name: telomerase activity namespace: molecular_function def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence." [GOC:krc] comment: Consider also annotating to the molecular function term 'telomeric DNA binding ; GO:0042162'. xref: EC:2.7.7.- xref: GO:0003720 xref: Reactome:10567 is_a: CCO:F0000457 ! RNA-directed DNA polymerase activity [Term] id: CCO:F0000307 name: telomeric template RNA reverse transcriptase activity namespace: molecular_function def: "Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template." [EC:2.7.7.49, PMID:11812242] synonym: "telomerase, catalyst" EXACT [] xref: GO:0003721 is_a: CCO:F0000457 ! RNA-directed DNA polymerase activity relationship: part_of CCO:F0000306 ! telomerase activity [Term] id: CCO:F0000308 name: RNA binding namespace: molecular_function def: "Interacting selectively with an RNA molecule or a portion thereof." [GOC:mah] subset: goslim_candida subset: goslim_generic subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0003723 is_a: CCO:F0000273 ! nucleic acid binding [Term] id: CCO:F0000309 name: RNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of an RNA helix." [GOC:jl] comment: Consider also annotating to the molecular function term 'RNA binding ; GO:0003723'. subset: gosubset_prok xref: EC:2.7.7.- xref: GO:0003724 xref: Reactome:7008 is_a: CCO:F0000803 ! helicase activity [Term] id: CCO:F0000310 name: double-stranded RNA binding namespace: molecular_function def: "Interacting selectively with double-stranded RNA." [GOC:jl] subset: gosubset_prok xref: GO:0003725 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0000311 name: double-stranded RNA adenosine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule." [GOC:mah] subset: gosubset_prok synonym: "double-stranded RNA specific editase activity" RELATED [] xref: GO:0003726 xref: GO:0003971 xref: Reactome:10576 is_a: CCO:F0000485 ! adenosine deaminase activity [Term] id: CCO:F0000312 name: single-stranded RNA binding namespace: molecular_function def: "Interacting selectively with single-stranded RNA." [GOC:jl] xref: GO:0003727 xref: GO:0003728 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0000313 name: mRNA binding namespace: molecular_function def: "Interacting selectively with pre-messenger RNA (pre-mRNA) or messenger RNA (mRNA)." [GOC:jl] subset: gosubset_prok xref: GO:0003729 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0000314 name: mRNA 3'-UTR binding namespace: molecular_function def: "Interacting selectively with the 3' untranslated region of an mRNA molecule." [GOC:mah] synonym: "mRNA 3' UTR binding" EXACT [] xref: GO:0003730 is_a: CCO:F0000313 ! mRNA binding [Term] id: CCO:F0000315 name: structural constituent of ribosome namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the ribosome." [GOC:mah] comment: Note that this term may be used to annotate ribosomal RNAs as well as ribosomal proteins. subset: gosubset_prok synonym: "ribosomal protein" BROAD [] synonym: "ribosomal RNA" RELATED [] xref: GO:0003735 xref: GO:0003736 xref: GO:0003737 xref: GO:0003738 xref: GO:0003739 xref: GO:0003740 xref: GO:0003741 xref: GO:0003742 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0000316 name: translation initiation factor activity namespace: molecular_function def: "Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0003743 xref: GO:0003744 xref: GO:0003745 xref: Reactome:10611 is_a: CCO:F0001739 ! translation factor activity, nucleic acid binding [Term] id: CCO:F0000317 name: translation elongation factor activity namespace: molecular_function def: "Functions in chain elongation during polypeptide synthesis at the ribosome." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0003746 xref: GO:0008182 xref: GO:0008183 xref: Reactome:10616 is_a: CCO:F0001739 ! translation factor activity, nucleic acid binding [Term] id: CCO:F0000318 name: translation release factor activity namespace: molecular_function def: "Involved in catalyzing the release of a nascent polypeptide chain from a ribosome." [ISBN:0198547684] subset: gosubset_prok xref: GO:0003747 xref: GO:0003748 xref: GO:0003749 is_a: CCO:F0001699 ! translation termination factor activity [Term] id: CCO:F0000319 name: peptidyl-prolyl cis-trans isomerase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0)." [EC:5.2.1.8] subset: gosubset_prok synonym: "cis-trans proline isomerase activity" EXACT [] synonym: "cyclophilin activity" RELATED [EC:5.2.1.8] synonym: "cyclophilin-type peptidyl-prolyl cis-trans isomerase activity" NARROW [] synonym: "FK506-sensitive peptidyl-prolyl cis-trans isomerase" NARROW [] synonym: "immunophilin" RELATED [] synonym: "parvulin" RELATED [] synonym: "peptide bond isomerase activity" EXACT [EC:5.2.1.8] synonym: "peptidyl-prolyl isomerase B reaction" RELATED [] synonym: "peptidylproline cis-trans-isomerase activity" EXACT [EC:5.2.1.8] synonym: "peptidylprolyl cis-trans isomerase activity" EXACT [EC:5.2.1.8] synonym: "peptidylprolyl isomerase activity" EXACT [EC:5.2.1.8] synonym: "PPIase activity" EXACT [EC:5.2.1.8] synonym: "rotamase activity" EXACT [EC:5.2.1.8] xref: EC:5.2.1.8 xref: GO:0003755 xref: GO:0004752 xref: MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0000320 name: protein disulfide isomerase activity namespace: molecular_function def: "Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins." [EC:5.3.4.1] subset: gosubset_prok synonym: "protein cysteine-thiol oxidation" RELATED [] synonym: "protein disulfide-isomerase" BROAD [EC:5.3.4.1] synonym: "protein disulfide-isomerase reaction" EXACT [EC:5.3.4.1] synonym: "protein disulphide isomerase activity" EXACT [] synonym: "S-S rearrangase activity" RELATED [EC:5.3.4.1] xref: EC:5.3.4.1 xref: GO:0003756 xref: MetaCyc:5.3.4.1-RXN xref: MetaCyc:DISULISOM-RXN is_a: CCO:F0003424 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups is_a: CCO:F0003426 ! intramolecular oxidoreductase activity, transposing S-S bonds [Term] id: CCO:F0000321 name: motor activity namespace: molecular_function def: "Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate." [GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0003774 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0000322 name: microtubule motor activity namespace: molecular_function def: "Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)." [GOC:mah, ISBN:0815316194] comment: Consider also annotating to the molecular function term 'microtubule binding ; GO:0008017'. synonym: "axonemal motor activity" NARROW [] synonym: "dynein" BROAD [] synonym: "dynein ATPase activity" NARROW [] synonym: "kinesin" BROAD [] synonym: "kinesin motor activity" NARROW [] synonym: "kinetochore motor activity" NARROW [] xref: GO:0003777 is_a: CCO:F0000321 ! motor activity [Term] id: CCO:F0000323 name: actin binding namespace: molecular_function def: "Interacting selectively with monomeric or multimeric forms of actin, including actin filaments." [GOC:clt] subset: goslim_generic synonym: "membrane associated actin binding" NARROW [] xref: GO:0003779 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0000324 name: actin monomer binding namespace: molecular_function def: "Interacting selectively with monomeric actin, also known as G-actin." [GOC:ai] synonym: "G actin binding" EXACT [] xref: GO:0003785 is_a: CCO:F0000323 ! actin binding [Term] id: CCO:F0000325 name: actin lateral binding namespace: molecular_function def: "Interacting selectively with an actin filament along its length." [GOC:mah] xref: GO:0003786 is_a: CCO:F0008035 ! actin filament binding [Term] id: CCO:F0000326 name: lysozyme activity namespace: molecular_function def: "Catalysis of the hydrolysis of the 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of the prokaryotes cell walls and between N-acetyl-D-glucosamine residues in chitodextrins." [EC:3.2.1.17] subset: gosubset_prok synonym: "1,4-N-acetylmuramidase activity" EXACT [] synonym: "globulin G" RELATED [EC:3.2.1.17] synonym: "globulin G1" RELATED [EC:3.2.1.17] synonym: "L-7001" RELATED [EC:3.2.1.17] synonym: "lysozyme g" RELATED [EC:3.2.1.17] synonym: "mucopeptide glucohydrolase activity" EXACT [] synonym: "mucopeptide N-acetylmuramoylhydrolase activity" EXACT [] synonym: "muramidase activity" EXACT [] synonym: "N,O-diacetylmuramidase activity" EXACT [] synonym: "peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [EC:3.2.1.17] synonym: "PR1-lysozyme" RELATED [EC:3.2.1.17] xref: EC:3.2.1.17 xref: GO:0003796 xref: MetaCyc:3.2.1.17-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0000327 name: coagulation factor VIIa activity namespace: molecular_function def: "Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa, and on factor IX to form factor IXa beta." [EC:3.4.21.21, PMID:12496253] synonym: "activated blood coagulation factor VII" RELATED [EC:3.4.21.21] synonym: "blood coagulation factor VII activity" EXACT [] synonym: "blood-coagulation factor VIIa" RELATED [EC:3.4.21.21] xref: EC:3.4.21.21 xref: GO:0003802 xref: MetaCyc:3.4.21.21-RXN xref: Reactome:11520 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000328 name: coagulation factor IXa activity namespace: molecular_function def: "Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa." [EC:3.4.21.22] synonym: "activated blood coagulation factor XI" RELATED [EC:3.4.21.22] synonym: "activated blood-coagulation factor IX" RELATED [EC:3.4.21.22] synonym: "activated christmas factor" RELATED [EC:3.4.21.22] synonym: "autoprothrombin II" RELATED [EC:3.4.21.22] synonym: "blood coagulation factor IX activity" EXACT [] synonym: "blood platelet cofactor II" RELATED [EC:3.4.21.22] synonym: "blood-coagulation factor IXa" RELATED [EC:3.4.21.22] synonym: "Christmas factor activity" EXACT [EC:3.4.21.22] xref: EC:3.4.21.22 xref: GO:0003803 xref: MetaCyc:3.4.21.22-RXN xref: Reactome:11522 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000329 name: coagulation factor Xa activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin, and on factor VII, which it converts to a two-chain form (factor VIIa)." [EC:3.4.21.6, GOC:jl, PMID:7354023] synonym: "activated blood-coagulation factor X" RELATED [EC:3.4.21.6] synonym: "activated factor X" RELATED [EC:3.4.21.6] synonym: "activated Stuart-Prower factor" RELATED [EC:3.4.21.6] synonym: "autoprothrombin C" RELATED [EC:3.4.21.6] synonym: "blood coagulation factor X activity" EXACT [] synonym: "factor Xa" RELATED [EC:3.4.21.6] synonym: "plasma thromboplastin" RELATED [EC:3.4.21.6] synonym: "prothrombase activity" EXACT [EC:3.4.21.6] synonym: "prothrombinase activity" EXACT [EC:3.4.21.6] synonym: "Stuart factor" RELATED [EC:3.4.21.6] synonym: "Stuart factor activity" EXACT [EC:3.4.21.6] synonym: "thrombokinase activity" EXACT [EC:3.4.21.6] synonym: "thromboplastin" RELATED [EC:3.4.21.6] xref: EC:3.4.21.6 xref: GO:0003804 xref: MetaCyc:3.4.21.6-RXN xref: Reactome:11523 is_a: CCO:F0000698 ! serine-type endopeptidase activity is_a: CCO:F0004479 ! prothrombin activator activity [Term] id: CCO:F0000330 name: coagulation factor XIa activity namespace: molecular_function def: "Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa." [EC:3.4.21.27] synonym: "activated blood-coagulation factor XI" RELATED [EC:3.4.21.27] synonym: "activated plasma thromboplastin antecedent" RELATED [EC:3.4.21.27] synonym: "blood coagulation factor XI activity" EXACT [] synonym: "blood-coagulation factor XIa" RELATED [EC:3.4.21.27] synonym: "plasma thromboplastin antecedent activity" EXACT [EC:3.4.21.27] xref: EC:3.4.21.27 xref: GO:0003805 xref: MetaCyc:3.4.21.27-RXN xref: Reactome:11530 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000331 name: coagulation factor XIIa activity namespace: molecular_function def: "Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa." [EC:3.4.21.38] synonym: "activated beta blood-coagulation factor XII" RELATED [EC:3.4.21.38] synonym: "blood coagulation factor XII activity" EXACT [] synonym: "blood-coagulation factor XIIabeta" RELATED [EC:3.4.21.38] synonym: "blood-coagulation factor XIIf" RELATED [EC:3.4.21.38] synonym: "hageman factor (activated)" RELATED [EC:3.4.21.38] synonym: "hageman factor activity" EXACT [EC:3.4.21.38] synonym: "hageman factor beta-fragment" RELATED [EC:3.4.21.38] synonym: "hageman factor fragment HFf" RELATED [EC:3.4.21.38] synonym: "kallikreinogen activator" RELATED [EC:3.4.21.38] synonym: "prealbumin activator" RELATED [EC:3.4.21.38] synonym: "prekallikrein activator" RELATED [EC:3.4.21.38] xref: EC:3.4.21.38 xref: GO:0003806 xref: MetaCyc:3.4.21.38-RXN xref: Reactome:11532 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000332 name: plasma kallikrein activity namespace: molecular_function def: "Catalysis of the selective cleavage of Arg-Xaa and Lys-Xaa bonds, including Lys-Arg and Arg-Ser bonds in (human) kininogen to release bradykinin." [EC:3.4.21.34] synonym: "bradykininogenase" BROAD [EC:3.4.21.34] synonym: "callicrein" RELATED [EC:3.4.21.34] synonym: "depot-padutin" RELATED [EC:3.4.21.34] synonym: "dilminal D" RELATED [EC:3.4.21.34] synonym: "glumorin" RELATED [EC:3.4.21.34] synonym: "kallidinogenase" BROAD [EC:3.4.21.34] synonym: "kallikrein" RELATED [EC:3.4.21.34] synonym: "kallikrein I" RELATED [EC:3.4.21.34] synonym: "kallikrein II" RELATED [EC:3.4.21.34] synonym: "kininogenase" BROAD [EC:3.4.21.34] synonym: "kininogenin activity" RELATED [EC:3.4.21.34] synonym: "onokrein P" RELATED [EC:3.4.21.34] synonym: "padreatin" RELATED [EC:3.4.21.34] synonym: "padutin" RELATED [EC:3.4.21.34] synonym: "panceatic kallikrein" RELATED [EC:3.4.21.34] synonym: "serum kallikrein activity" EXACT [EC:3.4.21.34] synonym: "urinary kallikrein" RELATED [EC:3.4.21.34] synonym: "urokallikrein" RELATED [EC:3.4.21.34] xref: EC:3.4.21.34 xref: GO:0003807 xref: MetaCyc:3.4.21.34-RXN xref: Reactome:11535 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000333 name: protein C (activated) activity namespace: molecular_function def: "Catalysis of the degradation of blood coagulation factors Va and VIIIa." [EC:3.4.21.69] synonym: "activated blood coagulation factor XIV activity" EXACT [EC:3.4.21.69] synonym: "activated protein C" RELATED [EC:3.4.21.69] synonym: "autoprothrombin II-A" RELATED [EC:3.4.21.69] synonym: "autoprothrombin IIA activity" EXACT [EC:3.4.21.69] synonym: "blood-coagulation factor XIVa" RELATED [EC:3.4.21.69] synonym: "GSAPC" RELATED [EC:3.4.21.69] synonym: "protein Ca" RELATED [EC:3.4.21.69] xref: EC:3.4.21.69 xref: GO:0003808 xref: MetaCyc:3.4.21.69-RXN xref: Reactome:11537 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000334 name: thrombin activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Arg-Gly; activates fibrinogen to fibrin and releases fibrinopeptide A and B." [EC:3.4.21.5] synonym: "activated blood-coagulation factor II" RELATED [EC:3.4.21.5] synonym: "beta-thrombin" RELATED [EC:3.4.21.5] synonym: "blood-coagulation factor IIa" RELATED [EC:3.4.21.5] synonym: "E thrombin" RELATED [EC:3.4.21.5] synonym: "factor IIa" RELATED [EC:3.4.21.5] synonym: "fibrinogenase activity" EXACT [EC:3.4.21.5] synonym: "gamma-thrombin" RELATED [EC:3.4.21.5] synonym: "thrombase activity" EXACT [EC:3.4.21.5] synonym: "thrombin-C" RELATED [EC:3.4.21.5] synonym: "thrombofort" RELATED [EC:3.4.21.5] synonym: "topical" RELATED [EC:3.4.21.5] synonym: "tropostasin" RELATED [EC:3.4.21.5] xref: EC:3.4.21.5 xref: GO:0003809 xref: MetaCyc:3.4.21.5-RXN xref: Reactome:11540 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000335 name: protein-glutamine gamma-glutamyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links." [EC:2.3.2.13, RESID:AA0124] subset: gosubset_prok synonym: "factor XIIIa" RELATED [EC:2.3.2.13] synonym: "fibrin stabilizing factor" RELATED [EC:2.3.2.13] synonym: "fibrinoligase activity" EXACT [] synonym: "glutaminylpeptide gamma-glutamyltransferase activity" EXACT [EC:2.3.2.13] synonym: "polyamine transglutaminase activity" RELATED [EC:2.3.2.13] synonym: "protein-glutamine:amine gamma-glutamyltransferase" EXACT [EC:2.3.2.13] synonym: "R-glutaminyl-peptide:amine gamma-glutamyl transferase activity" EXACT [EC:2.3.2.13] synonym: "TGase activity" EXACT [] synonym: "tissue transglutaminase" NARROW [EC:2.3.2.13] synonym: "transglutaminase activity" EXACT [] xref: EC:2.3.2.13 xref: GO:0003810 xref: MetaCyc:2.3.2.13-RXN xref: Reactome:11549 xref: RESID:AA0124 is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0000336 name: alternative-complement-pathway C3/C5 convertase activity namespace: molecular_function def: "Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b." [EC:3.4.21.47] synonym: "(C3b)n,Bb" RELATED [EC:3.4.21.47] synonym: "(CVF)-dependent glycine-rich-beta-glucoprotein" RELATED [EC:3.4.21.47] synonym: "alternative complement pathway C3(C5) convertase activity" EXACT [EC:3.4.21.47] synonym: "C3 convertase activity" BROAD [EC:3.4.21.47] synonym: "C3 proactivator" RELATED [EC:3.4.21.47] synonym: "C3b,Bb,CVF,Bb,C5 convertase activity" EXACT [EC:3.4.21.47] synonym: "C5 convertase activity" BROAD [EC:3.4.21.47] synonym: "cobra venom factor-dependent C3 convertase" NARROW [EC:3.4.21.47] synonym: "complement C 3(C 5) convertase (amplification)" EXACT [EC:3.4.21.47] synonym: "complement component C3/C5 convertase (alternative) activity" EXACT [EC:3.4.21.47] synonym: "complement factor B activity" EXACT [EC:3.4.21.47] synonym: "CVF,Bb" RELATED [EC:3.4.21.47] synonym: "glycine-rich beta-glycoprotein" RELATED [EC:3.4.21.47] synonym: "heat-labile factor" RELATED [EC:3.4.21.47] synonym: "proenzyme factor B" EXACT [] synonym: "properdin factor B activity" EXACT [EC:3.4.21.47] xref: EC:3.4.21.47 xref: GO:0003812 xref: MetaCyc:3.4.21.47-RXN xref: Reactome:11550 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000337 name: classical-complement-pathway C3/C5 convertase activity namespace: molecular_function def: "Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b." [EC:3.4.21.43] synonym: "C3 convertase activity" BROAD [EC:3.4.21.43] synonym: "C42" RELATED [EC:3.4.21.43] synonym: "C423" RELATED [EC:3.4.21.43] synonym: "C4b,2a" RELATED [EC:3.4.21.43] synonym: "C4b,2a,3b" RELATED [EC:3.4.21.43] synonym: "C5 convertase activity" BROAD [EC:3.4.21.43] synonym: "complement C2 activity" BROAD [EC:3.4.21.43] synonym: "complement C3 convertase activity" EXACT [EC:3.4.21.43] synonym: "complement C42" RELATED [EC:3.4.21.43] xref: EC:3.4.21.43 xref: GO:0003813 xref: MetaCyc:3.4.21.43-RXN xref: Reactome:11551 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000338 name: complement component C1r activity namespace: molecular_function def: "Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42)." [EC:3.4.21.41] synonym: "activated complement C1r" RELATED [EC:3.4.21.41] synonym: "C1r esterase activity" EXACT [EC:3.4.21.41] synonym: "complement subcomponent C1r" RELATED [EC:3.4.21.41] xref: EC:3.4.21.41 xref: GO:0003815 xref: MetaCyc:3.4.21.41-RXN xref: Reactome:11553 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000339 name: complement component C1s activity namespace: molecular_function def: "Catalysis of the cleavage of component C4 to C4a and C4b (Arg-Ala bond), and component C2 to C2a and C2b (Lys-Lys or Arg-Lys bond)." [EC:3.4.21.42] synonym: "activated complement C1s" RELATED [EC:3.4.21.42] synonym: "C1 esterase activity" EXACT [EC:3.4.21.42] synonym: "C1s esterase activity" EXACT [EC:3.4.21.42] synonym: "complement C1s" RELATED [EC:3.4.21.42] synonym: "complement subcomponent C1s" RELATED [EC:3.4.21.42] xref: EC:3.4.21.42 xref: GO:0003816 xref: MetaCyc:3.4.21.42-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000340 name: complement factor D activity namespace: molecular_function def: "Catalysis of the cleavage of component factor B (Arg-Lys) when in complex with C3b or with cobra venom factor (CVF)." [EC:3.4.21.46] synonym: "adipsin" EXACT [] synonym: "C3 convertase activator activity" EXACT [EC:3.4.21.46] synonym: "C3 proactivator convertase activity" EXACT [EC:3.4.21.46] synonym: "factor D" RELATED [EC:3.4.21.46] synonym: "factor D (complement)" RELATED [EC:3.4.21.46] synonym: "properdin factor D esterase activity" EXACT [EC:3.4.21.46] xref: EC:3.4.21.46 xref: GO:0003817 xref: MetaCyc:3.4.21.46-RXN xref: Reactome:11557 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000341 name: complement factor I activity namespace: molecular_function def: "Catalysis of the inactivation of complement subcomponents C3b, iC3b and C4b by proteolytic cleavage." [EC:3.4.21.45] synonym: "C3b inactivator activity" NARROW [EC:3.4.21.45] synonym: "C3b/C4b inactivator activity" EXACT [EC:3.4.21.45] synonym: "C3bINA" RELATED [EC:3.4.21.45] synonym: "complement C3b inactivator" RELATED [EC:3.4.21.45] synonym: "complement C3b/C4b inactivator" RELATED [EC:3.4.21.45] synonym: "complement C4b inactivator" RELATED [EC:3.4.21.45] synonym: "complement C4bi" RELATED [EC:3.4.21.45] synonym: "complement component C3b inactivator activity" EXACT [EC:3.4.21.45] synonym: "conglutinogen-activating factor C" RELATED [EC:3.4.21.45] synonym: "factor I" RELATED [EC:3.4.21.45] xref: EC:3.4.21.45 xref: GO:0003818 xref: MetaCyc:3.4.21.45-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000342 name: antigen binding namespace: molecular_function def: "Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: goslim_pir synonym: "antibody" RELATED [] synonym: "B cell receptor activity" RELATED [] synonym: "immunoglobulin" RELATED [] synonym: "opsonin activity" RELATED [] xref: GO:0003823 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0000343 name: catalytic activity namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: gosubset_prok synonym: "enzyme activity" RELATED [] xref: GO:0003824 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0000344 name: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate." [EC:2.4.1.15] subset: gosubset_prok synonym: "alpha,alpha-trehalose phosphate synthase (UDP-forming)" EXACT [EC:2.4.1.15] synonym: "phosphotrehalose-uridine diphosphate transglucosylase activity" EXACT [EC:2.4.1.15] synonym: "transglucosylase activity" EXACT [] synonym: "trehalose 6-phosphate synthase activity" EXACT [] synonym: "trehalose 6-phosphate synthetase activity" EXACT [] synonym: "trehalose phosphate synthase activity" EXACT [EC:2.4.1.15] synonym: "trehalose phosphate synthetase activity" EXACT [EC:2.4.1.15] synonym: "trehalose phosphate-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] synonym: "trehalose-P synthetase activity" EXACT [EC:2.4.1.15] synonym: "trehalose-phosphate synthase activity" EXACT [] synonym: "trehalose-phosphate synthetase activity" EXACT [] synonym: "trehalosephosphate-UDP glucosyl transferase activity" EXACT [] synonym: "trehalosephosphate-UDP glucosyltransferase activity" EXACT [] synonym: "UDP-glucose-glucose-phosphate glucosyltransferase activity" EXACT [] synonym: "UDP-glucose-glucosephosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] synonym: "UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [] synonym: "UDPglucose-glucose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] synonym: "UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.15] synonym: "uridine diphosphoglucose phosphate glucosyltransferase activity" EXACT [EC:2.4.1.15] xref: EC:2.4.1.15 xref: GO:0003825 xref: MetaCyc:TREHALOSE6PSYN-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0000345 name: alpha-ketoacid dehydrogenase activity namespace: molecular_function subset: gosubset_prok xref: GO:0003826 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0000346 name: alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2 = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(R1)-beta-D-mannosyl-R2." [EC:2.4.1.101] synonym: "alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.101] synonym: "alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.101] synonym: "alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [] synonym: "GnTI" RELATED [EC:2.4.1.101] synonym: "GNTI activity" EXACT [EC:2.4.1.101] synonym: "N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] synonym: "UDP-N-acetyl-D-glucosamine:3-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.101] synonym: "UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] synonym: "UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.101] synonym: "uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.101] xref: EC:2.4.1.101 xref: GO:0003827 xref: MetaCyc:2.4.1.101-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0000347 name: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R." [EC:2.4.99.8] synonym: "alpha-2,8-sialyltransferase activity" EXACT [EC:2.4.99.8] synonym: "alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity" EXACT [] synonym: "CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.8] synonym: "CMP-NeuAc:LM1(alpha2-8) sialyltranferase activity" EXACT [EC:2.4.99.8] synonym: "cytidine monophosphoacetylneuraminate-ganglioside GM3" RELATED [EC:2.4.99.8] synonym: "ganglioside GD3 synthase activity" EXACT [EC:2.4.99.8] synonym: "ganglioside GD3 synthetase sialyltransferase activity" EXACT [EC:2.4.99.8] synonym: "GD3 synthase activity" EXACT [EC:2.4.99.8] synonym: "SAT-2" RELATED [EC:2.4.99.8] xref: EC:2.4.99.8 xref: GO:0003828 xref: MetaCyc:2.4.99.8-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0000348 name: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R." [EC:2.4.1.102] synonym: "beta(6)-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] synonym: "beta6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] synonym: "core 2 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] synonym: "core 6-beta-GlcNAc-transferase A" RELATED [EC:2.4.1.102] synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity" EXACT [EC:2.4.1.102] synonym: "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.102] synonym: "uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] xref: EC:2.4.1.102 xref: GO:0003829 xref: MetaCyc:2.4.1.102-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0000349 name: beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R." [EC:2.4.1.144] subset: gosubset_prok synonym: "beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.144] synonym: "beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.144] synonym: "GnTIII activity" EXACT [EC:2.4.1.144] synonym: "N-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.144] synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.144] synonym: "UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.144] synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.144] synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III" RELATED [EC:2.4.1.144] xref: EC:2.4.1.144 xref: GO:0003830 xref: MetaCyc:2.4.1.144-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0000350 name: beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide." [EC:2.4.1.38] synonym: "beta-N-acetyl-beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "GalT activity" RELATED [EC:2.4.1.38] synonym: "glycoprotein 4-beta-galactosyl-transferase activity" EXACT [EC:2.4.1.38] synonym: "glycoprotein 4-beta-galactosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "glycoprotein beta-galactosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "thyroid galactosyltransferase activity" NARROW [EC:2.4.1.38] synonym: "thyroid glycoprotein beta-galactosyltransferase" NARROW [EC:2.4.1.38] synonym: "UDP-D-xylose:glycoprotein (D-xylose to the 3,6-disubstituted mannose of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 2-beta-D-xylosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "UDP-D-xylose:glycoprotein (D-xylose to the 3,6-disubstituted mannose of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 2-beta-D-xylosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "UDP-galactose--glycoprotein galactosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "UDPgalactose-glycoprotein galactosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.38] synonym: "uridine diphosphogalactose-glycoprotein galactosyltransferase activity" EXACT [EC:2.4.1.38] xref: EC:2.4.1.38 xref: GO:0003831 xref: MetaCyc:2.4.1.38-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0000351 name: beta-alanyl-dopamine hydrolase activity namespace: molecular_function def: "Catalysis of the conversion of beta-alanyl dopamine to dopamine (3,4-dihydroxyphenylethylamine)." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:12957543] synonym: "N-beta-alanyl-dopamine hydrolase activity" EXACT [] synonym: "NBAD hydrolase activity" EXACT [] xref: GO:0003832 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0000352 name: beta-alanyl-dopamine synthase activity namespace: molecular_function def: "Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine)." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:12957543] synonym: "N-beta-alanyl dopamine synthetase activity" EXACT [] synonym: "NBAD transferase activity" EXACT [] xref: GO:0003833 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0000353 name: beta-carotene 15,15'-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: beta-carotene + O2 = 2 retinal." [EC:1.14.99.36] comment: Note that this function was formerly EC:1.13.11.21. synonym: "beta-carotene 15,15'-dioxygenase activity" EXACT [] synonym: "beta-carotene:oxygen 15,15'-oxidoreductase (bond-cleaving)" EXACT [EC:1.14.99.36] synonym: "carotene 15,15'-dioxygenase activity" EXACT [EC:1.14.99.36] synonym: "carotene dioxygenase activity" EXACT [EC:1.14.99.36] xref: EC:1.14.99.36 xref: GO:0003834 xref: MetaCyc:BETA-CAROTENE-15 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0000354 name: beta-galactoside alpha-2,6-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine." [EC:2.4.99.1] synonym: "beta-galactosamide alpha-2,6-sialyltransferase activity" EXACT [] synonym: "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.1] synonym: "CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.1] xref: EC:2.4.99.1 xref: GO:0003835 xref: MetaCyc:2.4.99.1-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0000355 name: beta-galactoside alpha-2,3-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R." [EC:2.4.99.4] synonym: "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase activity" EXACT [EC:2.4.99.4] synonym: "CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase activity" EXACT [EC:2.4.99.4] xref: EC:2.4.99.4 xref: GO:0003836 xref: MetaCyc:2.4.99.4-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0000356 name: beta-ureidopropionase activity namespace: molecular_function def: "Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3." [EC:3.5.1.6] subset: gosubset_prok synonym: "N-carbamoyl-beta-alanine amidohydrolase activity" EXACT [EC:3.5.1.6] xref: EC:3.5.1.6 xref: GO:0003837 xref: MetaCyc:BETA-UREIDOPROPIONASE-RXN xref: Reactome:11609 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000357 name: sterol 24-C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol." [EC:2.1.1.41] subset: gosubset_prok synonym: "24-sterol C-methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "delta(24)-methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "delta(24)-sterol C-methyltransferase activity" EXACT [] synonym: "delta(24)-sterol methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "delta24-methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "delta24-sterol methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "phytosterol methyltransferase activity" NARROW [EC:2.1.1.41] synonym: "S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "S-adenosyl-4-methionine:sterol delta24-methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity" EXACT [EC:2.1.1.41] synonym: "SMT1 activity" NARROW [EC:2.1.1.41] synonym: "zymosterol-24-methyltransferase activity" NARROW [EC:2.1.1.41] xref: EC:2.1.1.41 xref: GO:0003838 xref: MetaCyc:RXN3O-178 is_a: CCO:F0001756 ! C-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0000358 name: gamma-glutamylcyclotransferase activity namespace: molecular_function def: "Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid." [EC:2.3.2.4] synonym: "(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)" EXACT [EC:2.3.2.4] synonym: "gamma-glutamyl-amino acid cyclotransferase activity" EXACT [EC:2.3.2.4] synonym: "gamma-L-glutamylcyclotransferase activity" EXACT [EC:2.3.2.4] synonym: "L-glutamic cyclase activity" EXACT [EC:2.3.2.4] xref: EC:2.3.2.4 xref: GO:0003839 xref: MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0000359 name: gamma-glutamyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid." [EC:2.3.2.2] subset: gosubset_prok synonym: "(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase activity" EXACT [EC:2.3.2.2] synonym: "alpha-glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] synonym: "gamma-glutamyl peptidyltransferase activity" EXACT [EC:2.3.2.2] synonym: "gamma-glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] synonym: "gamma-GPT" RELATED [EC:2.3.2.2] synonym: "gamma-GT" RELATED [EC:2.3.2.2] synonym: "gamma-GTP" RELATED [EC:2.3.2.2] synonym: "glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] synonym: "L-gamma-glutamyl transpeptidase activity" EXACT [EC:2.3.2.2] synonym: "L-gamma-glutamyltransferase activity" EXACT [EC:2.3.2.2] synonym: "L-glutamyltransferase activity" EXACT [EC:2.3.2.2] xref: EC:2.3.2.2 xref: GO:0003840 xref: MetaCyc:GAMMA-GLUTAMYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0000360 name: 1-acylglycerol-3-phosphate O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate." [EC:2.3.1.51] subset: gosubset_prok synonym: "1-acyl-sn-glycero-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.51] synonym: "1-acyl-sn-glycerol 3-phosphate acyltransferase activity" EXACT [EC:2.3.1.51] synonym: "1-acyl-sn-glycerol-3-phosphate acyltransferase activity" EXACT [] synonym: "1-acylglycero-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.51] synonym: "1-acylglycerolphosphate acyltransferase activity" EXACT [EC:2.3.1.51] synonym: "1-acylglycerophosphate acyltransferase activity" EXACT [EC:2.3.1.51] synonym: "acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity" EXACT [EC:2.3.1.51] synonym: "lysophosphatidate acyltransferase activity" EXACT [] synonym: "lysophosphatidic acid-acyltransferase activity" EXACT [EC:2.3.1.51] xref: EC:2.3.1.51 xref: GO:0003841 xref: GO:0004469 xref: MetaCyc:RXN-1623 is_a: CCO:F0003134 ! acylglycerol O-acyltransferase activity [Term] id: CCO:F0000361 name: 1-pyrroline-5-carboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H+." [EC:1.5.1.12] subset: gosubset_prok synonym: "1-pyrroline dehydrogenase" BROAD [EC:1.5.1.12] synonym: "1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.12] synonym: "delta1-pyrroline-5-carboxylate dehydrogenase activity" EXACT [EC:1.5.1.12] synonym: "L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity" EXACT [EC:1.5.1.12] synonym: "pyrroline-5-carboxylate dehydrogenase activity" EXACT [EC:1.5.1.12] synonym: "pyrroline-5-carboxylic acid dehydrogenase activity" EXACT [EC:1.5.1.12] xref: EC:1.5.1.12 xref: GO:0003842 xref: MetaCyc:PYRROLINECARBDEHYDROG-RXN xref: Reactome:11630 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000362 name: 1,3-beta-glucan synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + 1,3-beta-D-glucosyl(n) = UDP + 1,3-beta-D-glucosyl(n+1)." [EC:2.4.1.34] synonym: "(1,3)-beta-glucan (callose) synthase activity" EXACT [EC:2.4.1.34] synonym: "1,3-beta-D-glucan synthase activity" EXACT [EC:2.4.1.34] synonym: "1,3-beta-D-glucan synthetase activity" EXACT [EC:2.4.1.34] synonym: "1,3-beta-D-glucan-UDP glucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "1,3-beta-glucan-uridine diphosphoglucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "beta-1,3-glucan synthase activity" EXACT [] synonym: "beta-1,3-glucan synthetase activity" EXACT [EC:2.4.1.34] synonym: "callose synthase activity" EXACT [] synonym: "callose synthetase activity" EXACT [EC:2.4.1.34] synonym: "GS-II" RELATED [EC:2.4.1.34] synonym: "paramylon synthetase" RELATED [EC:2.4.1.34] synonym: "UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "UDP-glucose-1,3-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "UDP-glucose-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "UDP-glucose:(1,3)beta-glucan synthase activity" EXACT [EC:2.4.1.34] synonym: "UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "UDPglucose-1,3-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.34] synonym: "uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.34] xref: EC:2.4.1.34 xref: GO:0003843 xref: GO:0009981 xref: MetaCyc:1 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0000363 name: 1,4-alpha-glucan branching enzyme activity namespace: molecular_function def: "Catalysis of the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain." [EC:2.4.1.18] subset: gosubset_prok synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity" EXACT [] synonym: "1,4-glucan-6-(1,4-glucano)-transferase activity" EXACT [] synonym: "alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase activity" EXACT [EC:2.4.1.18] synonym: "alpha-glucan-branching glycosyltransferase activity" EXACT [EC:2.4.1.18] synonym: "amylo-(1,4 to 1,6)transglucosidase activity" EXACT [EC:2.4.1.18] synonym: "amylo-(1,4->1,6)-transglycosylase activity" EXACT [EC:2.4.1.18] synonym: "amylose isomerase activity" EXACT [EC:2.4.1.18] synonym: "branching enzyme activity" RELATED [EC:2.4.1.18] synonym: "branching glycosyltransferase activity" EXACT [EC:2.4.1.18] synonym: "enzymatic branching factor" RELATED [EC:2.4.1.18] synonym: "enzyme Q" RELATED [EC:2.4.1.18] synonym: "glucosan transglycosylase activity" EXACT [EC:2.4.1.18] synonym: "glycogen branching enzyme activity" EXACT [EC:2.4.1.18] synonym: "plant branching enzyme" RELATED [EC:2.4.1.18] synonym: "Q-enzyme" RELATED [EC:2.4.1.18] synonym: "starch branching enzyme" RELATED [EC:2.4.1.18] xref: EC:2.4.1.18 xref: GO:0003844 xref: MetaCyc:GLYCOGEN-BRANCH-RXN xref: Reactome:11632 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0000364 name: 11-beta-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+." [EC:1.1.1.146, PMID:15761036] subset: gosubset_prok synonym: "11beta-hydroxy steroid dehydrogenase" EXACT [EC:1.1.1.146] synonym: "11beta-hydroxysteroid dehydrogenase" EXACT [EC:1.1.1.146] synonym: "beta-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.146] synonym: "corticosteroid 11-reductase" RELATED [EC:1.1.1.146] synonym: "corticosteroid 11beta-dehydrogenase" RELATED [EC:1.1.1.146] synonym: "dehydrogenase, 11beta-hydroxy steroid" EXACT [EC:1.1.1.146] xref: GO:0003845 is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000365 name: 2-acylglycerol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol." [EC:2.3.1.22] synonym: "acyl coenzyme A-monoglyceride acyltransferase activity" EXACT [EC:2.3.1.22] synonym: "acyl-CoA:2-acylglycerol O-acyltransferase activity" EXACT [EC:2.3.1.22] synonym: "acylglycerol palmitoyltransferase activity" EXACT [EC:2.3.1.22] synonym: "monoacylglycerol acyltransferase activity" EXACT [EC:2.3.1.22] synonym: "monoglyceride acyltransferase activity" EXACT [EC:2.3.1.22] xref: EC:2.3.1.22 xref: GO:0003846 xref: MetaCyc:2-ACYLGLYCEROL-O-ACYLTRANSFERASE-RXN is_a: CCO:F0003134 ! acylglycerol O-acyltransferase activity [Term] id: CCO:F0000366 name: 1-alkyl-2-acetylglycerophosphocholine esterase activity namespace: molecular_function def: "Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate." [EC:3.1.1.47] subset: gosubset_prok synonym: "1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase activity" EXACT [EC:3.1.1.47] synonym: "1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase activity" EXACT [EC:3.1.1.47] synonym: "2-acetyl-1-alkylglycerophosphocholine esterase activity" EXACT [] synonym: "alkylacetyl-GPC:acetylhydrolase activity" EXACT [EC:3.1.1.47] synonym: "LDL-associated phospholipase A(2) activity" RELATED [EC:3.1.1.47] synonym: "LDL-associated phospholipase A2" RELATED [EC:3.1.1.47] synonym: "LDL-PLA(2) activity" RELATED [EC:3.1.1.47] synonym: "LDL-PLA2" RELATED [EC:3.1.1.47] synonym: "PAF 2-acylhydrolase activity" RELATED [EC:3.1.1.47] synonym: "PAF acetylhydrolase activity" RELATED [EC:3.1.1.47] synonym: "platelet-activating factor acetylhydrolase activity" RELATED [EC:3.1.1.47] xref: EC:3.1.1.47 xref: GO:0003847 xref: MetaCyc:3.1.1.47-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0000367 name: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine." [EC:2.7.6.3] subset: gosubset_prok synonym: "2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity" EXACT [] synonym: "6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity" EXACT [EC:2.7.6.3] synonym: "6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity" EXACT [EC:2.7.6.3] synonym: "7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity" EXACT [EC:2.7.6.3] synonym: "7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity" EXACT [EC:2.7.6.3] synonym: "7,8-dihydroxymethylpterin-pyrophosphokinase activity" EXACT [EC:2.7.6.3] synonym: "ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity" EXACT [EC:2.7.6.3] synonym: "H2-pteridine-CH2OH pyrophosphokinase activity" EXACT [EC:2.7.6.3] synonym: "HPPK" RELATED [EC:2.7.6.3] synonym: "hydroxymethyldihydropteridine pyrophosphokinase activity" EXACT [EC:2.7.6.3] xref: EC:2.7.6.3 xref: GO:0003848 xref: MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN is_a: CCO:F0003350 ! diphosphotransferase activity [Term] id: CCO:F0000368 name: 3-deoxy-7-phosphoheptulonate synthase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate." [EC:2.5.1.54] comment: Note that this function was formerly EC:4.1.2.15. subset: gosubset_prok synonym: "2-dehydro-3-deoxy-phosphoheptonate aldolase activity" EXACT [EC:2.5.1.54] synonym: "2-dehydro-3-deoxyphosphoheptonate aldolase activity" EXACT [] synonym: "2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase activity" EXACT [EC:2.5.1.54] synonym: "3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase activity" EXACT [EC:2.5.1.54] synonym: "3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase activity" EXACT [EC:2.5.1.54] synonym: "3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase activity" EXACT [EC:2.5.1.54] synonym: "7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate" RELATED [EC:2.5.1.54] synonym: "7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.54] synonym: "7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.54] synonym: "D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.54] synonym: "D-erythrose-4-phosphate-lyase activity" RELATED [EC:2.5.1.54] synonym: "DAH7-P synthase activity" EXACT [EC:2.5.1.54] synonym: "DAHP synthase activity" EXACT [EC:2.5.1.54] synonym: "deoxy-D-arabino-heptulosonate-7-phosphate synthetase activity" EXACT [EC:2.5.1.54] synonym: "DHAP synthase activity" EXACT [EC:2.5.1.54] synonym: "DS-Co activity" RELATED [EC:2.5.1.54] synonym: "DS-Mn activity" RELATED [EC:2.5.1.54] synonym: "KDPH synthase activity" EXACT [EC:2.5.1.54] synonym: "KDPH synthetase activity" EXACT [EC:2.5.1.54] synonym: "phospho-2-dehydro-3-deoxyheptonate aldolase activity" EXACT [EC:2.5.1.54] synonym: "phospho-2-keto-3-deoxyheptanoate aldolase activity" EXACT [EC:2.5.1.54] synonym: "phospho-2-keto-3-deoxyheptonate aldolase activity" EXACT [EC:2.5.1.54] synonym: "phospho-2-keto-3-deoxyheptonic aldolase activity" EXACT [EC:2.5.1.54] synonym: "phospho-2-oxo-3-deoxyheptonate aldolase activity" EXACT [EC:2.5.1.54] synonym: "phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)" EXACT [EC:2.5.1.54] xref: EC:2.5.1.54 xref: GO:0003849 xref: MetaCyc:DAHPSYN-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000369 name: 2-deoxyglucose-6-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2-deoxy-D-glucose 6-phosphate + H2O = 2-deoxy-D-glucose + phosphate." [EC:3.1.3.68] synonym: "2-deoxy-D-glucose-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.68] synonym: "2-deoxyglucose-6-phosphate phosphatase activity" EXACT [EC:3.1.3.68] xref: EC:3.1.3.68 xref: GO:0003850 xref: MetaCyc:3.1.3.68-RXN is_a: CCO:F0004126 ! carbohydrate phosphatase activity [Term] id: CCO:F0000370 name: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine." [EC:2.4.1.45] synonym: "cerebroside synthase activity" EXACT [EC:2.4.1.45] synonym: "UDP-galactose-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.45] synonym: "UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity" EXACT [EC:2.4.1.45] synonym: "UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.45] synonym: "UDPgalactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity" EXACT [EC:2.4.1.45] synonym: "UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.45] synonym: "UDPgalactose:ceramide galactosyltransferase activity" EXACT [EC:2.4.1.45] synonym: "uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.45] xref: EC:2.4.1.45 xref: GO:0003851 xref: MetaCyc:2.4.1.45-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0000371 name: 2-isopropylmalate synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA." [EC:2.3.3.13] comment: Note that this function was formerly EC:4.1.3.12. subset: gosubset_prok synonym: "3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity" EXACT [EC:2.3.3.13] synonym: "acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.13] synonym: "alpha-IPM synthetase activity" EXACT [EC:2.3.3.13] synonym: "alpha-isopropylmalate synthase activity" EXACT [EC:2.3.3.13] synonym: "alpha-isopropylmalate synthetase activity" EXACT [EC:2.3.3.13] synonym: "alpha-isopropylmalic synthetase activity" EXACT [EC:2.3.3.13] synonym: "isopropylmalate synthase activity" EXACT [EC:2.3.3.13] synonym: "isopropylmalate synthetase activity" EXACT [EC:2.3.3.13] xref: EC:2.3.3.13 xref: GO:0003852 xref: MetaCyc:2-ISOPROPYLMALATESYN-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0000372 name: 2-methylacyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor." [EC:1.3.99.12] synonym: "2-methyl branched chain acyl-CoA dehydrogenase activity" EXACT [EC:1.3.99.12] synonym: "2-methylbutanoyl-CoA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.99.12] synonym: "2-methylbutanoyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.3.99.12] synonym: "branched-chain acyl-CoA dehydrogenase activity" RELATED [EC:1.3.99.12] xref: EC:1.3.99.12 xref: GO:0003853 xref: MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN is_a: CCO:F0000480 ! acyl-CoA dehydrogenase activity [Term] id: CCO:F0000373 name: 3-beta-hydroxy-delta5-steroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-beta-hydroxy-delta(5)-steroid + NAD+ = 3-oxo-delta(5)-steroid + NADH + H+." [EC:1.1.1.145] subset: gosubset_prok synonym: "3-beta-hydroxy-5-ene steroid dehydrogenase activity" EXACT [EC:1.1.1.145] synonym: "3-beta-hydroxy-D5-steroid dehydrogenase activity" EXACT [] synonym: "3beta-HSDH" RELATED [EC:1.1.1.145] synonym: "3beta-hydroxy steroid dehydrogenase/isomerase activity" EXACT [EC:1.1.1.145] synonym: "3beta-hydroxy-5-ene steroid dehydrogenase activity" EXACT [EC:1.1.1.145] synonym: "3beta-hydroxy-5-ene-steroid dehydrogenase activity" EXACT [EC:1.1.1.145] synonym: "3beta-hydroxy-5-ene-steroid oxidoreductase activity" EXACT [EC:1.1.1.145] synonym: "3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity" EXACT [EC:1.1.1.145] synonym: "3beta-hydroxy-delta5-C27-steroid oxidoreductase" BROAD [EC:1.1.1.145] synonym: "3beta-hydroxy-delta5-steroid dehydrogenase activity" EXACT [EC:1.1.1.145] synonym: "3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.145] synonym: "5-ene-3-beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.145] synonym: "delta5-3beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.145] synonym: "progesterone reductase activity" BROAD [EC:1.1.1.145] synonym: "steroid-delta5-3beta-ol dehydrogenase activity" EXACT [EC:1.1.1.145] xref: EC:1.1.1.145 xref: GO:0003854 xref: MetaCyc:1.1.1.145-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000374 name: 3-dehydroquinate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H2O." [EC:4.2.1.10] subset: gosubset_prok synonym: "3-dehydroquinase activity" EXACT [EC:4.2.1.10] synonym: "3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming)" EXACT [EC:4.2.1.10] synonym: "3-dehydroquinate hydro-lyase activity" EXACT [EC:4.2.1.10] synonym: "3-dehydroquinate hydrolase activity" EXACT [EC:4.2.1.10] synonym: "5-dehydroquinase activity" EXACT [EC:4.2.1.10] synonym: "5-dehydroquinate dehydratase activity" EXACT [EC:4.2.1.10] synonym: "5-dehydroquinate hydro-lyase activity" EXACT [EC:4.2.1.10] synonym: "dehydroquinase activity" EXACT [EC:4.2.1.10] synonym: "dehydroquinate dehydratase activity" EXACT [EC:4.2.1.10] synonym: "DHQase" EXACT [EC:4.2.1.10] xref: EC:4.2.1.10 xref: GO:0003855 xref: MetaCyc:3-DEHYDROQUINATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000375 name: 3-dehydroquinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3-deoxy-arabino-heptulosonate 7-phosphate = 3-dehydroquinate + phosphate." [EC:4.2.3.4] subset: gosubset_prok synonym: "3-dehydroquinate synthetase activity" EXACT [EC:4.2.3.4] synonym: "3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing)" EXACT [EC:4.2.3.4] synonym: "3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming)" EXACT [EC:4.2.3.4] synonym: "3-deoxy-arabino-heptulosonate-7-phosphate phosphate-lyase (cyclizing)" EXACT [EC:4.2.3.4] synonym: "5-dehydroquinate synthase activity" EXACT [EC:4.2.3.4] synonym: "5-dehydroquinic acid synthetase activity" EXACT [EC:4.2.3.4] synonym: "dehydroquinate synthase activity" EXACT [EC:4.2.3.4] xref: EC:4.2.3.4 xref: GO:0003856 xref: MetaCyc:3-DEHYDROQUINATE-SYNTHASE-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0000376 name: 3-hydroxyacyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+." [EC:1.1.1.35] comment: See also 'long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509'. subset: gosubset_prok synonym: "beta-hydroxyacyl dehydrogenase activity" EXACT [EC:1.1.1.35] synonym: "beta-hydroxyacyl-coenzyme A synthetase activity" EXACT [EC:1.1.1.35] synonym: "beta-hydroxyacylcoenzyme A dehydrogenase activity" EXACT [EC:1.1.1.35] synonym: "beta-hydroxybutyrylcoenzyme A dehydrogenase activity" EXACT [EC:1.1.1.35] synonym: "beta-keto-reductase activity" EXACT [EC:1.1.1.35] synonym: "beta-ketoacyl-CoA reductase" BROAD [EC:1.1.1.35] synonym: "L-3-hydroxyacyl CoA dehydrogenase activity" EXACT [EC:1.1.1.35] synonym: "L-3-hydroxyacyl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.35] xref: EC:1.1.1.35 xref: GO:0003857 xref: MetaCyc:OHACYL-COA-DEHYDROG-RXN xref: Reactome:11645 xref: UM-BBD_enzymeID:e0664 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000377 name: 3-hydroxybutyrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH + H+." [EC:1.1.1.30] subset: gosubset_prok synonym: "D-beta-hydroxybutyrate dehydrogenase activity" EXACT [EC:1.1.1.30] xref: EC:1.1.1.30 xref: GO:0003858 xref: MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN xref: Reactome:11646 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000378 name: 3-hydroxybutyryl-CoA dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O." [EC:4.2.1.55] subset: gosubset_prok synonym: "(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)" EXACT [EC:4.2.1.55] synonym: "(3R)-3-hydroxybutanoyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.55] synonym: "crotonase activity" EXACT [EC:4.2.1.55] synonym: "D-3-hydroxybutyryl coenzyme A dehydratase activity" EXACT [EC:4.2.1.55] synonym: "D-3-hydroxybutyryl-CoA dehydratase activity" EXACT [EC:4.2.1.55] synonym: "enoyl coenzyme A hydrase (D)" BROAD [EC:4.2.1.55] xref: EC:4.2.1.55 xref: GO:0003859 xref: MetaCyc:3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000379 name: 3-hydroxyisobutyryl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate." [EC:3.1.2.4] subset: gosubset_prok synonym: "3-hydroxy-2-methylpropanoyl-CoA hydrolase activity" EXACT [EC:3.1.2.4] synonym: "3-hydroxy-isobutyryl CoA hydrolase activity" EXACT [EC:3.1.2.4] synonym: "HIB CoA deacylase activity" EXACT [EC:3.1.2.4] xref: EC:3.1.2.4 xref: GO:0003860 xref: MetaCyc:3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN xref: Reactome:11660 is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0000380 name: 3-isopropylmalate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 3-isopropylmalate = 2-isopropylmaleate + H2O." [EC:4.2.1.33] subset: gosubset_prok synonym: "(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)" EXACT [EC:4.2.1.33] synonym: "(2R,3S)-3-isopropylmalate hydro-lyase activity" EXACT [EC:4.2.1.33] synonym: "alpha-IPM isomerase activity" EXACT [EC:4.2.1.33] synonym: "alpha-isopropylmalate isomerase activity" EXACT [EC:4.2.1.33] synonym: "beta-isopropylmalate dehydratase activity" EXACT [EC:4.2.1.33] synonym: "isopropylmalate isomerase activity" EXACT [EC:4.2.1.33] xref: EC:4.2.1.33 xref: GO:0003861 xref: MetaCyc:3-ISOPROPYLMALISOM-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000381 name: 3-isopropylmalate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+." [EC:1.1.1.85] subset: gosubset_prok synonym: "(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.85] synonym: "3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.85] synonym: "beta-IPM dehydrogenase activity" EXACT [EC:1.1.1.85] synonym: "beta-isopropylmalate dehydrogenase activity" EXACT [EC:1.1.1.85] synonym: "beta-isopropylmalic enzyme" RELATED [EC:1.1.1.85] synonym: "IMDH activity" EXACT [EC:1.1.1.85] synonym: "IPMDH" RELATED [EC:1.1.1.85] synonym: "threo-Ds-3-isopropylmalate dehydrogenase activity" EXACT [EC:1.1.1.85] xref: EC:1.1.1.85 xref: GO:0003862 xref: MetaCyc:3-ISOPROPYLMALDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000382 name: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity namespace: molecular_function def: "Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2." [EC:1.2.4.4] subset: gosubset_prok synonym: "2-oxoisocaproate dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "2-oxoisovalerate (lipoate) dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity" EXACT [EC:1.2.4.4] synonym: "3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)" EXACT [EC:1.2.4.4] synonym: "3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity" EXACT [EC:1.2.4.4] synonym: "alpha-keto-alpha-methylvalerate dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "alpha-ketoisocaproate dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "alpha-ketoisocaproic dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "alpha-ketoisovalerate dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "alpha-oxoisocaproate dehydrogenase activity" EXACT [EC:1.2.4.4] synonym: "BCKDH activity" RELATED [EC:1.2.4.4] synonym: "BCOAD activity" RELATED [EC:1.2.4.4] synonym: "branched chain keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] synonym: "branched-chain (-2-oxoacid) dehydrogenase (BCD) activity" RELATED [EC:1.2.4.4] synonym: "branched-chain 2-keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] synonym: "branched-chain 2-oxo acid dehydrogenase activity" RELATED [EC:1.2.4.4] synonym: "branched-chain alpha-keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] synonym: "branched-chain alpha-oxo acid dehydrogenase activity" RELATED [EC:1.2.4.4] synonym: "branched-chain keto acid dehydrogenase activity" RELATED [EC:1.2.4.4] synonym: "branched-chain ketoacid dehydrogenase activity" RELATED [EC:1.2.4.4] synonym: "dehydrogenase, 2-oxoisovalerate (lipoate) activity" EXACT [EC:1.2.4.4] synonym: "dehydrogenase, branched chain alpha-keto acid activity" RELATED [EC:1.2.4.4] xref: EC:1.2.4.4 xref: GO:0003863 xref: MetaCyc:1.2.4.4-RXN xref: Reactome:11663 is_a: CCO:F0003226 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Term] id: CCO:F0000383 name: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate." [EC:2.1.2.11] subset: gosubset_prok synonym: "5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] synonym: "5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] synonym: "alpha-ketoisovalerate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] synonym: "dehydropantoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] synonym: "ketopantoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] synonym: "oxopantoate hydroxymethyltransferase activity" EXACT [EC:2.1.2.11] xref: EC:2.1.2.11 xref: GO:0003864 xref: MetaCyc:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0000384 name: 3-oxo-5-alpha-steroid 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor." [EC:1.3.99.5] synonym: "3-keto-delta4-steroid-5alpha-reductase activity" EXACT [EC:1.3.99.5] synonym: "3-oxo-5alpha-steroid 4-dehydrogenase activity" EXACT [EC:1.3.99.5] synonym: "3-oxo-5alpha-steroid delta4-dehydrogenase activity" EXACT [EC:1.3.99.5] synonym: "3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity" EXACT [EC:1.3.99.5] synonym: "3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity" EXACT [EC:1.3.99.5] synonym: "3-oxosteroid delta4-dehydrogenase" BROAD [EC:1.3.99.5] synonym: "4-ene-3-ketosteroid-5alpha-oxidoreductase activity" EXACT [EC:1.3.99.5] synonym: "5alpha-reductase" BROAD [EC:1.3.99.5] synonym: "delta4-3-keto steroid 5alpha-reductase activity" EXACT [EC:1.3.99.5] synonym: "delta4-3-ketosteroid5alpha-oxidoreductase activity" EXACT [EC:1.3.99.5] synonym: "delta4-3-oxo steroid reductase activity" EXACT [EC:1.3.99.5] synonym: "delta4-3-oxosteroid-5alpha-reductase" BROAD [EC:1.3.99.5] synonym: "delta4-5alpha-dehydrogenase activity" EXACT [EC:1.3.99.5] synonym: "steroid 5 alpha reductase" BROAD [EC:1.3.99.5] synonym: "steroid 5-alpha-reductase activity" BROAD [EC:1.3.99.5] synonym: "steroid 5alpha-reductase" BROAD [EC:1.3.99.5] synonym: "steroid delta4-5alpha-reductase activity" EXACT [EC:1.3.99.5] synonym: "testosterone 5alpha-reductase" BROAD [EC:1.3.99.5] xref: EC:1.3.99.5 xref: GO:0003865 xref: MetaCyc:1.3.99.5-RXN is_a: CCO:F0005255 ! steroid dehydrogenase activity, acting on the CH-CH group of donors [Term] id: CCO:F0000385 name: 3-phosphoshikimate 1-carboxyvinyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate." [EC:2.5.1.19] subset: gosubset_prok synonym: "3-enol-pyruvoylshikimate-5-phosphate synthase activity" EXACT [EC:2.5.1.19] synonym: "5-enolpyruvylshikimate-3-phosphate synthase activity" EXACT [EC:2.5.1.19] synonym: "EPSP synthase activity" EXACT [EC:2.5.1.19] synonym: "phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity" EXACT [EC:2.5.1.19] xref: EC:2.5.1.19 xref: GO:0003866 xref: MetaCyc:2.5.1.19-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000386 name: 4-aminobutyrate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid." [EC:2.6.1.19, GOC:mah] subset: gosubset_prok synonym: "4-aminobutanoate transaminase activity" EXACT [] synonym: "4-aminobutyrate aminotransferase activity" EXACT [] synonym: "4-aminobutyric acid aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "aminobutyrate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "aminobutyrate transaminase activity" EXACT [EC:2.6.1.19] synonym: "beta-alanine aminotransferase" RELATED [EC:2.6.1.19] synonym: "beta-alanine--oxoglutarate aminotransferase activity" RELATED [EC:2.6.1.19] synonym: "beta-alanine-oxoglutarate transaminase activity" RELATED [EC:2.6.1.19] synonym: "GABA aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "GABA transaminase activity" EXACT [] synonym: "GABA transferase activity" EXACT [EC:2.6.1.19] synonym: "gamma-amino-N-butyrate transaminase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyrate aminotransaminase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyrate transaminase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyric acid aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyric acid transaminase activity" EXACT [] synonym: "gamma-aminobutyric transaminase activity" EXACT [EC:2.6.1.19] synonym: "glutamate-succinic semialdehyde transaminase activity" EXACT [EC:2.6.1.19] xref: EC:2.6.1.19 xref: GO:0003867 xref: MetaCyc:GABATRANSAM-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000387 name: 4-hydroxyphenylpyruvate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2." [EC:1.13.11.27] subset: gosubset_prok synonym: "4-hydroxyphenylpyruvate hydroxylase activity" EXACT [EC:1.13.11.27] synonym: "4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)" EXACT [EC:1.13.11.27] synonym: "4-hydroxyphenylpyruvic acid dioxygenase activity" EXACT [EC:1.13.11.27] synonym: "p-hydroxyphenylpyruvate dioxygenase activity" EXACT [EC:1.13.11.27] synonym: "p-hydroxyphenylpyruvate hydroxylase activity" EXACT [EC:1.13.11.27] synonym: "p-hydroxyphenylpyruvate oxidase activity" EXACT [EC:1.13.11.27] synonym: "p-hydroxyphenylpyruvic acid hydroxylase activity" EXACT [EC:1.13.11.27] synonym: "p-hydroxyphenylpyruvic hydroxylase activity" EXACT [EC:1.13.11.27] synonym: "p-hydroxyphenylpyruvic oxidase activity" EXACT [EC:1.13.11.27] xref: EC:1.13.11.27 xref: GO:0003868 xref: MetaCyc:4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN xref: Reactome:11670 xref: UM-BBD_enzymeID:e0126 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0000388 name: 4-nitrophenylphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate." [EC:3.1.3.41] subset: gosubset_prok synonym: "4-nitrophenylphosphate phosphohydrolase activity" EXACT [EC:3.1.3.41] synonym: "ecto-p-nitrophenyl phosphatase activity" EXACT [EC:3.1.3.41] synonym: "K-pNPPase activity" EXACT [EC:3.1.3.41] synonym: "nitrophenyl phosphatase activity" EXACT [EC:3.1.3.41] synonym: "NPPase activity" EXACT [EC:3.1.3.41] synonym: "p-nitrophenylphosphatase activity" EXACT [EC:3.1.3.41] synonym: "p-nitrophenylphosphate phosphohydrolase activity" EXACT [EC:3.1.3.41] synonym: "para-nitrophenyl phosphatase activity" EXACT [EC:3.1.3.41] synonym: "PNPPase activity" EXACT [EC:3.1.3.41] xref: EC:3.1.3.41 xref: GO:0003869 xref: MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000389 name: 5-aminolevulinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2." [EC:2.3.1.37] subset: gosubset_prok synonym: "5-aminolevulinate synthetase activity" EXACT [EC:2.3.1.37] synonym: "5-aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] synonym: "5-aminolevulinic acid synthetase activity" EXACT [EC:2.3.1.37] synonym: "ALA synthase activity" EXACT [EC:2.3.1.37] synonym: "ALA synthetase activity" EXACT [EC:2.3.1.37] synonym: "ALAS activity" EXACT [EC:2.3.1.37] synonym: "alpha-aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] synonym: "aminolevulinate synthase activity" EXACT [EC:2.3.1.37] synonym: "aminolevulinate synthetase activity" EXACT [EC:2.3.1.37] synonym: "aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] synonym: "aminolevulinic acid synthetase activity" EXACT [EC:2.3.1.37] synonym: "aminolevulinic synthetase activity" EXACT [EC:2.3.1.37] synonym: "delta-ALA synthetase activity" EXACT [EC:2.3.1.37] synonym: "delta-aminolevulinate synthase activity" EXACT [EC:2.3.1.37] synonym: "delta-aminolevulinate synthetase activity" EXACT [EC:2.3.1.37] synonym: "delta-aminolevulinic acid synthase activity" EXACT [EC:2.3.1.37] synonym: "delta-aminolevulinic acid synthetase activity" EXACT [EC:2.3.1.37] synonym: "delta-aminolevulinic synthetase activity" EXACT [EC:2.3.1.37] synonym: "succinyl-CoA:glycine C-succinyltransferase (decarboxylating)" EXACT [EC:2.3.1.37] xref: EC:2.3.1.37 xref: GO:0003870 xref: MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN xref: Reactome:11690 is_a: CCO:F0003324 ! N-succinyltransferase activity [Term] id: CCO:F0000390 name: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine." [EC:2.1.1.14] subset: gosubset_prok synonym: "5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.14] synonym: "cobalamin-independent methionine synthase activity" EXACT [EC:2.1.1.14] synonym: "homocysteine methylase activity" EXACT [EC:2.1.1.14] synonym: "MetE" RELATED [EC:2.1.1.14] synonym: "methionine synthase (cobalamin-independent) activity" EXACT [EC:2.1.1.14] synonym: "methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity" EXACT [EC:2.1.1.14] synonym: "methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity" EXACT [EC:2.1.1.14] synonym: "tetrahydropteroylglutamate-homocysteine transmethylase activity" EXACT [EC:2.1.1.14] synonym: "tetrahydropteroyltriglutamate methyltransferase activity" EXACT [EC:2.1.1.14] xref: EC:2.1.1.14 xref: GO:0003871 xref: MetaCyc:HOMOCYSMET-RXN is_a: CCO:F0001759 ! S-methyltransferase activity is_a: CCO:F0005621 ! 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity [Term] id: CCO:F0000391 name: 6-phosphofructokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate." [EC:2.7.1.11] subset: gosubset_prok synonym: "6-phosphofructokinase reduction" EXACT [] synonym: "6-phosphofructose 1-kinase activity" EXACT [EC:2.7.1.11] synonym: "ATP-dependent phosphofructokinase activity" EXACT [EC:2.7.1.11] synonym: "ATP:D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.11] synonym: "D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.11] synonym: "fructose 6-phosphate kinase activity" EXACT [EC:2.7.1.11] synonym: "fructose 6-phosphokinase activity" EXACT [EC:2.7.1.11] synonym: "nucleotide triphosphate-dependent phosphofructokinase activity" EXACT [EC:2.7.1.11] synonym: "PFK" RELATED [EC:2.7.1.11] synonym: "phospho-1,6-fructokinase activity" EXACT [EC:2.7.1.11] synonym: "phosphofructokinase (phosphorylating)" EXACT [EC:2.7.1.11] synonym: "phosphofructokinase I activity" EXACT [EC:2.7.1.11] synonym: "phosphohexokinase activity" BROAD [EC:2.7.1.11] xref: EC:2.7.1.11 xref: GO:0003872 xref: MetaCyc:6PFRUCTPHOS-RXN xref: Reactome:11692 is_a: CCO:F0001906 ! phosphofructokinase activity [Term] id: CCO:F0000392 name: 6-phosphofructo-2-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-fructose 6-phosphate = ADP + D-fructose 2,6-bisphosphate." [EC:2.7.1.105] synonym: "6-phosphofructo-2-kinase (phosphorylating)" EXACT [EC:2.7.1.105] synonym: "6-phosphofructose 2-kinase activity" EXACT [EC:2.7.1.105] synonym: "ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity" EXACT [EC:2.7.1.105] synonym: "ATP:D-fructose-6-phosphate 2-phosphotransferase activity" EXACT [EC:2.7.1.105] synonym: "fructose 6-phosphate 2-kinase activity" EXACT [EC:2.7.1.105] synonym: "phosphofructokinase 2 activity" EXACT [EC:2.7.1.105] xref: EC:2.7.1.105 xref: GO:0003873 xref: MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN xref: Reactome:11695 is_a: CCO:F0001906 ! phosphofructokinase activity [Term] id: CCO:F0000393 name: 6-pyruvoyltetrahydropterin synthase activity namespace: molecular_function def: "Catalysis of the reaction: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate." [EC:4.2.3.12] subset: gosubset_prok synonym: "2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity" EXACT [EC:4.2.3.12] synonym: "2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)" EXACT [EC:4.2.3.12] synonym: "6-pyruvoyl tetrahydrobiopterin synthase activity" EXACT [EC:4.2.3.12] synonym: "PTPS activity" EXACT [EC:4.2.3.12] xref: EC:4.2.3.12 xref: GO:0003874 xref: MetaCyc:4.2.3.12-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0000394 name: ADP-ribosylarginine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose." [EC:3.2.2.19] subset: gosubset_prok synonym: "ADP-ribose-L-arginine cleavage enzyme activity" EXACT [EC:3.2.2.19] synonym: "ADP-ribose-L-arginine cleaving enzyme activity" EXACT [EC:3.2.2.19] synonym: "ADPribosylarginine hydrolase activity" EXACT [] synonym: "N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] synonym: "nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] synonym: "omega-protein-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] synonym: "protein ADP-ribosylarginine hydrolase activity" EXACT [EC:3.2.2.19] synonym: "protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.19] xref: EC:3.2.2.19 xref: GO:0003875 xref: MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0000395 name: AMP deaminase activity namespace: molecular_function def: "Catalysis of the reaction: AMP + H2O = IMP + NH3." [EC:3.5.4.6] synonym: "5-adenylate deaminase activity" EXACT [EC:3.5.4.6] synonym: "5-adenylic acid deaminase activity" EXACT [EC:3.5.4.6] synonym: "5-AMP deaminase activity" EXACT [EC:3.5.4.6] synonym: "adenosine 5-monophosphate deaminase activity" EXACT [EC:3.5.4.6] synonym: "adenosine 5-phosphate aminohydrolase activity" EXACT [EC:3.5.4.6] synonym: "adenosine monophosphate deaminase activity" EXACT [EC:3.5.4.6] synonym: "adenyl deaminase activity" EXACT [EC:3.5.4.6] synonym: "adenylate aminohydrolase activity" EXACT [EC:3.5.4.6] synonym: "adenylate deaminase activity" EXACT [EC:3.5.4.6] synonym: "adenylate deaminase reaction" EXACT [] synonym: "adenylate desaminase activity" EXACT [EC:3.5.4.6] synonym: "adenylic acid deaminase activity" EXACT [EC:3.5.4.6] synonym: "adenylic deaminase activity" EXACT [EC:3.5.4.6] synonym: "AMP aminase activity" EXACT [EC:3.5.4.6] synonym: "AMP aminohydrolase activity" EXACT [EC:3.5.4.6] synonym: "myoadenylate deaminase activity" NARROW [EC:3.5.4.6] xref: EC:3.5.4.6 xref: GO:0003876 xref: MetaCyc:AMP-DEAMINASE-RXN xref: Reactome:11698 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000396 name: ATP adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate." [EC:2.7.7.53] subset: gosubset_prok synonym: "adenine triphosphate adenylyltransferase activity" EXACT [EC:2.7.7.53] synonym: "ADP:ATP adenylyltransferase activity" EXACT [] synonym: "AP-4-A phosphorylase activity" EXACT [EC:2.7.7.53] synonym: "bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming) activity" EXACT [EC:2.7.7.53] synonym: "diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase activity" EXACT [EC:2.7.7.53] synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming)" EXACT [EC:2.7.7.53] synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase activity" EXACT [EC:2.7.7.53] synonym: "diadenosinetetraphosphate alpha-beta-phosphorylase activity" EXACT [EC:2.7.7.53] synonym: "diadenosinetetraphosphate alphabeta-phosphorylase activity" EXACT [EC:2.7.7.53] synonym: "dinucleoside oligophosphate alphabeta-phosphorylase activity" EXACT [EC:2.7.7.53] xref: EC:2.7.7.53 xref: GO:0003877 xref: MetaCyc:ATP-ADENYLYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000397 name: ATP citrate synthase activity namespace: molecular_function def: "Catalysis of the reaction: ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA." [EC:2.3.3.8] comment: Note that this function was formerly EC:4.1.3.8. synonym: "acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [EC:2.3.3.8] synonym: "acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [EC:2.3.3.8] synonym: "acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [EC:2.3.3.8] synonym: "adenosine triphosphate citrate lyase activity" EXACT [EC:2.3.3.8] synonym: "ATP citrate (pro-S)-lyase activity" EXACT [EC:2.3.3.8] synonym: "ATP-citrate (pro-S)-lyase activity" EXACT [] synonym: "ATP-citrate (pro-S-)-lyase activity" EXACT [EC:2.3.3.8] synonym: "ATP-citric lyase activity" EXACT [EC:2.3.3.8] synonym: "ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [EC:2.3.3.8] synonym: "ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [EC:2.3.3.8] synonym: "citrate cleavage enzyme activity" RELATED [EC:2.3.3.8] synonym: "citrate-ATP lyase activity" EXACT [EC:2.3.3.8] synonym: "citric cleavage enzyme activity" RELATED [EC:2.3.3.8] xref: EC:2.3.3.8 xref: GO:0003878 xref: GO:0046913 xref: MetaCyc:ATP-CITRATE-(PRO-S-)-LYASE-RXN xref: MetaCyc:PWY-5172 is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0000398 name: ATP phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.17] subset: gosubset_prok synonym: "1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase activity" EXACT [EC:2.4.2.17] synonym: "adenosine triphosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyl ATP synthetase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyl-ATP diphosphorylase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyl-ATP pyrophosphorylase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyladenosine triphosphate pyrophosphorylase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyladenosine triphosphate synthetase activity" EXACT [EC:2.4.2.17] synonym: "phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.17] xref: EC:2.4.2.17 xref: GO:0003879 xref: MetaCyc:ATPPHOSPHORIBOSYLTRANS-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000399 name: C-terminal protein carboxyl methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to the carbon atom of the C-terminal residue of a protein." [PMID:8428937] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0003880 is_a: CCO:F0001813 ! protein methyltransferase activity [Term] id: CCO:F0000400 name: CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-diacylglycerol + myo-inositol = CMP + phosphatidyl-1D-myo-inositol." [EC:2.7.8.11] subset: gosubset_prok synonym: "CDP diglyceride-inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "CDP-DG:inositol transferase activity" EXACT [EC:2.7.8.11] synonym: "CDP-diacylglycerol--inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "CDP-diglyceride-inositol transferase activity" EXACT [EC:2.7.8.11] synonym: "CDP-diglyceride:inositol transferase activity" EXACT [EC:2.7.8.11] synonym: "CDPdiacylglycerol-inositol 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "cytidine diphosphodiglyceride-inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "cytidine diphosphoglyceride-inositol phosphatidyltransferase activity" EXACT [EC:2.7.8.11] synonym: "cytidine diphosphoglyceride-inositol transferase activity" EXACT [EC:2.7.8.11] synonym: "phosphatidylinositol synthase activity" EXACT [] xref: EC:2.7.8.11 xref: GO:0003881 xref: MetaCyc:2.7.8.11-RXN is_a: CCO:F0003607 ! CDP-alcohol phosphatidyltransferase activity [Term] id: CCO:F0000401 name: CDP-diacylglycerol-serine O-phosphatidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine." [EC:2.7.8.8] subset: gosubset_prok synonym: "CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "CDP-diglyceride-L-serine phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "CDP-diglyceride:serine phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "CDP-diglycerine-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "CDPdiacylglycerol-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "CDPdiglyceride-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity" EXACT [EC:2.7.8.8] synonym: "phosphatidylserine synthase activity" EXACT [EC:2.7.8.8] synonym: "phosphatidylserine synthetase activity" EXACT [EC:2.7.8.8] synonym: "PS synthase activity" EXACT [EC:2.7.8.8] synonym: "serine exchange enzyme" BROAD [] xref: EC:2.7.8.8 xref: GO:0003882 xref: MetaCyc:PHOSPHASERSYN-RXN is_a: CCO:F0003607 ! CDP-alcohol phosphatidyltransferase activity [Term] id: CCO:F0000402 name: CTP synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP." [EC:6.3.4.2] subset: gosubset_prok synonym: "CTP synthetase activity" EXACT [EC:6.3.4.2] synonym: "cytidine 5'-triphosphate synthetase activity" EXACT [EC:6.3.4.2] synonym: "cytidine triphosphate synthetase activity" EXACT [EC:6.3.4.2] synonym: "uridine triphosphate aminase activity" EXACT [EC:6.3.4.2] synonym: "UTP--ammonia ligase activity" EXACT [EC:6.3.4.2] synonym: "UTP:ammonia ligase (ADP-forming)" EXACT [EC:6.3.4.2] xref: EC:6.3.4.2 xref: GO:0003883 xref: MetaCyc:CTPSYN-RXN xref: Reactome:11718 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0000403 name: D-amino-acid oxidase activity namespace: molecular_function def: "Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + H2O2." [EC:1.4.3.3] subset: gosubset_prok synonym: "D-amino-acid:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.3] synonym: "L-amino acid:O2 oxidoreductase activity" EXACT [EC:1.4.3.3] synonym: "new yellow enzyme" RELATED [EC:1.4.3.3] xref: EC:1.4.3.3 xref: GO:0003884 xref: MetaCyc:D-AMINO-ACID-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0000404 name: D-arabinono-1,4-lactone oxidase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinono-1,4-lactone + O2 = D-erythro-ascorbate + H2O2." [EC:1.1.3.37] subset: gosubset_prok synonym: "D-arabinono-1,4-lactone:oxygen oxidoreductase activity" EXACT [EC:1.1.3.37] xref: EC:1.1.3.37 xref: GO:0003885 xref: MetaCyc:1.1.3.37-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0000405 name: DNA (cytosine-5-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine." [EC:2.1.1.37] comment: Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37). subset: gosubset_prok synonym: "cytosine 5-methyltransferase activity" EXACT [EC:2.1.1.37] synonym: "cytosine DNA methylase activity" BROAD [EC:2.1.1.37] synonym: "cytosine DNA methyltransferase activity" BROAD [EC:2.1.1.37] synonym: "cytosine-specific DNA methyltransferase activity" EXACT [EC:2.1.1.37] synonym: "deoxyribonucleic (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.37] synonym: "deoxyribonucleic acid (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.37] synonym: "deoxyribonucleic methylase activity" BROAD [EC:2.1.1.37] synonym: "DNA 5-cytosine methylase activity" EXACT [EC:2.1.1.37] synonym: "DNA cytosine C(5) methylase activity" EXACT [EC:2.1.1.37] synonym: "DNA cytosine c5 methylase activity" EXACT [EC:2.1.1.37] synonym: "DNA cytosine C5 methylase activity" EXACT [EC:2.1.1.37] synonym: "DNA cytosine methylase activity" BROAD [EC:2.1.1.37] synonym: "DNA-cytosine 5-methylase activity" EXACT [EC:2.1.1.37] synonym: "DNA-cytosine methyltransferase activity" BROAD [EC:2.1.1.37] synonym: "methylphosphotriester-DNA methyltransferase activity" RELATED [EC:2.1.1.37] synonym: "modification methylase activity" RELATED [EC:2.1.1.37] synonym: "restriction-modification system activity" RELATED [EC:2.1.1.37] synonym: "S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.37] synonym: "site-specific DNA-methyltransferase (cytosine-specific) activity" NARROW [EC:2.1.1.37] synonym: "type II DNA methylase activity" RELATED [EC:2.1.1.37] xref: EC:2.1.1.37 xref: GO:0003886 xref: GO:0008326 xref: MetaCyc:2.1.1.73-RXN xref: MetaCyc:DNA-(CYTOSINE-5-)-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity is_a: CCO:F0002339 ! DNA-methyltransferase activity [Term] id: CCO:F0000406 name: DNA-directed DNA polymerase activity namespace: molecular_function def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer." [EC:2.7.7.7, ISBN:0198547684] subset: gosubset_prok synonym: "alpha DNA polymerase activity" NARROW [] synonym: "beta DNA polymerase activity" NARROW [] synonym: "delta DNA polymerase activity" NARROW [] synonym: "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.7] synonym: "deoxyribonucleic acid duplicase activity" EXACT [EC:2.7.7.7] synonym: "deoxyribonucleic duplicase activity" EXACT [EC:2.7.7.7] synonym: "deoxyribonucleic polymerase I" NARROW [EC:2.7.7.7] synonym: "DNA duplicase activity" EXACT [EC:2.7.7.7] synonym: "DNA nucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.7] synonym: "DNA polymerase alpha" NARROW [EC:2.7.7.7] synonym: "DNA polymerase beta" NARROW [EC:2.7.7.7] synonym: "DNA polymerase gamma" NARROW [EC:2.7.7.7] synonym: "DNA polymerase I" NARROW [EC:2.7.7.7] synonym: "DNA polymerase II" NARROW [EC:2.7.7.7] synonym: "DNA polymerase III" NARROW [EC:2.7.7.7] synonym: "DNA polymerase V activity" NARROW [] synonym: "DNA replicase activity" EXACT [EC:2.7.7.7] synonym: "DNA-dependent DNA polymerase activity" EXACT [EC:2.7.7.7] synonym: "duplicase" BROAD [EC:2.7.7.7] synonym: "epsilon DNA polymerase activity" NARROW [] synonym: "eta DNA polymerase activity" NARROW [] synonym: "gamma DNA-directed DNA polymerase activity" NARROW [] synonym: "iota DNA polymerase activity" NARROW [] synonym: "kappa DNA polymerase activity" NARROW [] synonym: "Klenow fragment" NARROW [EC:2.7.7.7] synonym: "lambda DNA polymerase activity" NARROW [] synonym: "mu DNA polymerase activity" NARROW [] synonym: "nu DNA polymerase activity" NARROW [] synonym: "sequenase" RELATED [EC:2.7.7.7] synonym: "sigma DNA polymerase activity" NARROW [] synonym: "Taq DNA polymerase" NARROW [EC:2.7.7.7] synonym: "Taq Pol I" NARROW [EC:2.7.7.7] synonym: "Tca DNA polymerase" NARROW [EC:2.7.7.7] synonym: "theta DNA polymerase activity" NARROW [] synonym: "zeta DNA polymerase activity" NARROW [] xref: EC:2.7.7.- xref: EC:2.7.7.7 xref: GO:0003887 xref: GO:0003888 xref: GO:0003889 xref: GO:0003890 xref: GO:0003891 xref: GO:0003893 xref: GO:0003894 xref: GO:0003895 xref: GO:0008723 xref: GO:0015999 xref: GO:0016000 xref: GO:0016448 xref: GO:0016449 xref: GO:0016450 xref: GO:0016451 xref: GO:0016452 xref: GO:0019984 xref: MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN xref: Reactome:11722 xref: Reactome:11738 xref: Reactome:26112 xref: Reactome:69114 is_a: CCO:F0005510 ! DNA polymerase activity [Term] id: CCO:F0000407 name: DNA primase activity namespace: molecular_function def: "Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases. Catalyzed by a DNA-directed RNA polymerase that forms a complex with alpha DNA polymerase." [GOC:mah, ISBN:0716720094] subset: gosubset_prok xref: EC:2.7.7.- xref: GO:0003896 xref: GO:0003897 xref: GO:0003898 is_a: CCO:F0000408 ! DNA-directed RNA polymerase activity [Term] id: CCO:F0000408 name: DNA-directed RNA polymerase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [EC:2.7.7.6] subset: gosubset_prok synonym: "C ribonucleic acid formation factors" RELATED [EC:2.7.7.6] synonym: "C RNA formation factors" RELATED [EC:2.7.7.6] synonym: "deoxyribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [EC:2.7.7.6] synonym: "DNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.6] synonym: "DNA-dependent RNA nucleotidyltransferase activity" EXACT [EC:2.7.7.6] synonym: "DNA-dependent RNA polymerase activity" EXACT [EC:2.7.7.6] synonym: "DNA-directed RNA polymerase I activity" NARROW [] synonym: "DNA-directed RNA polymerase II activity" NARROW [] synonym: "DNA-directed RNA polymerase III activity" NARROW [] synonym: "nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.6] synonym: "RNA nucleotidyltransferase (DNA-directed) activity" EXACT [EC:2.7.7.6] synonym: "RNA polymerase I activity" NARROW [EC:2.7.7.6] synonym: "RNA polymerase II activity" NARROW [EC:2.7.7.6] synonym: "RNA polymerase III activity" NARROW [EC:2.7.7.6] synonym: "transcriptase" BROAD [EC:2.7.7.6] xref: EC:2.7.7.6 xref: GO:0000129 xref: GO:0003899 xref: MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN xref: Reactome:11745 is_a: CCO:F0005511 ! RNA polymerase activity [Term] id: CCO:F0000409 name: deoxyribodipyrimidine photo-lyase activity namespace: molecular_function def: "Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). The enzyme catalyzes the reactivation by light of irradiated DNA. A similar reactivation of irradiated RNA is probably due to a separate enzyme." [EC:4.1.99.3] comment: Consider also annotating to the molecular function term 'damaged DNA binding ; GO:0003684'. subset: gosubset_prok synonym: "deoxyribocyclobutadipyrimidine pyrimidine-lyase activity" EXACT [EC:4.1.99.3] synonym: "deoxyribodipyrimidine photolyase activity" EXACT [] synonym: "deoxyribonucleate pyrimidine dimer lyase (photosensitive)" EXACT [EC:4.1.99.3] synonym: "deoxyribonucleic cyclobutane dipyrimidine photolyase activity" EXACT [EC:4.1.99.3] synonym: "deoxyribonucleic photolyase activity" EXACT [EC:4.1.99.3] synonym: "dipyrimidine photolyase (photosensitive)" EXACT [EC:4.1.99.3] synonym: "DNA cyclobutane dipyrimidine photolyase activity" EXACT [EC:4.1.99.3] synonym: "DNA-photoreactivating enzyme" RELATED [EC:4.1.99.3] synonym: "photolyase activity" EXACT [EC:4.1.99.3] synonym: "photoreactivating enzyme activity" RELATED [EC:4.1.99.3] synonym: "phr A photolyase activity" EXACT [EC:4.1.99.3] synonym: "PhrB photolyase activity" EXACT [EC:4.1.99.3] synonym: "PRE" RELATED [EC:4.1.99.3] xref: EC:4.1.99.3 xref: GO:0003904 xref: MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN is_a: CCO:F0000417 ! DNA photolyase activity [Term] id: CCO:F0000410 name: alkylbase DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of alkylated DNA; recognizes and removes alkylated purines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site. Enzyme has broad substrate specificity, being able to recognize alkylpurines, alkylpyrimidines or ethenopurines." [EC:3.2.2.21, GOC:elh, PMID:10872450, PMID:9224623] subset: gosubset_prok synonym: "3-methyladenine DNA glycosylase II" RELATED [EC:3.2.2.21] synonym: "AlkA" RELATED [EC:3.2.2.21] synonym: "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)" BROAD [EC:3.2.2.21] synonym: "alkylbase DNA glycosidase activity" EXACT [] synonym: "deoxyribonucleate 3-methyladenine glycosidase II" RELATED [EC:3.2.2.21] synonym: "DNA glycosidase II activity" EXACT [EC:3.2.2.21] synonym: "DNA-3-methyladenine glycosidase II activity" EXACT [] synonym: "DNA-3-methyladenine glycosylase II" RELATED [EC:3.2.2.21] xref: EC:3.2.2.21 xref: GO:0003905 xref: GO:0004036 xref: MetaCyc:3.2.2.21-RXN is_a: CCO:F0004051 ! DNA N-glycosylase activity [Term] id: CCO:F0000411 name: DNA-(apurinic or apyrimidinic site) lyase activity namespace: molecular_function def: "Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate." [EC:4.2.99.18] comment: Consider also annotating to the molecular function term 'damaged DNA binding ; GO:0003684'. subset: gosubset_prok synonym: "AP endonuclease class I activity" NARROW [EC:4.2.99.18] synonym: "AP lyase activity" EXACT [EC:4.2.99.18] synonym: "AP site-DNA 5'-phosphomonoester-lyase activity" EXACT [EC:4.2.99.18] synonym: "deoxyribonuclease (apurinic or apyrimidinic) activity" EXACT [EC:4.2.99.18] synonym: "DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity" EXACT [EC:4.2.99.18] synonym: "E. coli endonuclease III" RELATED [EC:4.2.99.18] synonym: "E.coli endonuclease III activity" NARROW [EC:4.2.99.18] synonym: "endodeoxyribonuclease (apurinic or apyrimidinic) activity" EXACT [EC:4.2.99.18] synonym: "endonuclease VIII activity" RELATED [] synonym: "micrococcus luteus UV endonuclease" NARROW [EC:4.2.99.18] synonym: "Micrococcus luteus UV endonuclease activity" NARROW [EC:4.2.99.18] synonym: "Phage-T(4) UV endonuclease activity" NARROW [EC:4.2.99.18] synonym: "phage-T4 UV endonuclease" BROAD [EC:4.2.99.18] synonym: "Phage-T4 UV endonuclease activity" NARROW [EC:4.2.99.18] synonym: "X-ray endonuclease III" RELATED [EC:4.2.99.18] xref: EC:4.2.99.18 xref: GO:0003906 xref: MetaCyc:4.2.99.18-RXN xref: Reactome:12450 is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0000412 name: methylated-DNA-[protein]-cysteine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine." [EC:2.1.1.63] comment: Consider also annotating to the molecular function term 'damaged DNA binding ; GO:0003684'. subset: gosubset_prok synonym: "6-O-methylguanine-DNA methyltransferase activity" EXACT [EC:2.1.1.63] synonym: "DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity" EXACT [] synonym: "DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity" EXACT [EC:2.1.1.63] synonym: "methylated-DNA-protein-cysteine S-methyltransferase activity" EXACT [EC:2.1.1.63] synonym: "MGMT" EXACT [] synonym: "O-6-methylguanine-DNA-alkyltransferase activity" EXACT [EC:2.1.1.63] synonym: "O6-alkylguanine-DNA alkyltransferase" BROAD [] xref: EC:2.1.1.63 xref: GO:0003908 xref: MetaCyc:2.1.1.63-RXN xref: Reactome:12455 is_a: CCO:F0001759 ! S-methyltransferase activity [Term] id: CCO:F0000413 name: DNA ligase activity namespace: molecular_function def: "Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another; requires an energy source such as ATP or NAD+." [ISBN:0716720094] subset: gosubset_prok xref: EC:6.5.1.- xref: GO:0003909 xref: Reactome:12459 is_a: CCO:F0003444 ! ligase activity, forming phosphoric ester bonds [Term] id: CCO:F0000414 name: DNA ligase (ATP) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m)." [EC:6.5.1.1] subset: gosubset_prok synonym: "deoxyribonucleate ligase" BROAD [EC:6.5.1.1] synonym: "deoxyribonucleic acid joinase" BROAD [EC:6.5.1.1] synonym: "deoxyribonucleic acid ligase" BROAD [EC:6.5.1.1] synonym: "deoxyribonucleic acid repair enzyme" RELATED [EC:6.5.1.1] synonym: "deoxyribonucleic acid-joining enzyme" RELATED [EC:6.5.1.1] synonym: "deoxyribonucleic joinase" BROAD [EC:6.5.1.1] synonym: "deoxyribonucleic ligase" BROAD [EC:6.5.1.1] synonym: "deoxyribonucleic repair enzyme" RELATED [EC:6.5.1.1] synonym: "deoxyribonucleic-joining enzyme" RELATED [EC:6.5.1.1] synonym: "DNA joinase activity" BROAD [EC:6.5.1.1] synonym: "DNA repair enzyme activity" RELATED [EC:6.5.1.1] synonym: "DNA-joining enzyme" RELATED [EC:6.5.1.1] synonym: "poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)" EXACT [EC:6.5.1.1] synonym: "polydeoxyribonucleotide synthase (ATP) activity" EXACT [EC:6.5.1.1] synonym: "polynucleotide ligase" BROAD [EC:6.5.1.1] synonym: "polynucleotide ligase (ATP) activity" EXACT [EC:6.5.1.1] synonym: "sealase activity" RELATED [EC:6.5.1.1] xref: EC:6.5.1.1 xref: GO:0003910 xref: MetaCyc:DNA-LIGASE-(ATP)-RXN is_a: CCO:F0000413 ! DNA ligase activity [Term] id: CCO:F0000415 name: DNA ligase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m)." [EC:6.5.1.2] subset: gosubset_prok synonym: "deoxyribonucleate ligase" BROAD [EC:6.5.1.2] synonym: "deoxyribonucleic acid joinase" BROAD [EC:6.5.1.2] synonym: "deoxyribonucleic acid ligase" BROAD [EC:6.5.1.2] synonym: "deoxyribonucleic joinase" BROAD [EC:6.5.1.2] synonym: "deoxyribonucleic ligase" BROAD [EC:6.5.1.2] synonym: "deoxyribonucleic repair enzyme" RELATED [EC:6.5.1.2] synonym: "deoxyribonucleic-joining enzyme" RELATED [EC:6.5.1.2] synonym: "DNA joinase activity" BROAD [EC:6.5.1.2] synonym: "DNA ligase (NAD)" EXACT [EC:6.5.1.2] synonym: "DNA repair enzyme activity" RELATED [EC:6.5.1.2] synonym: "DNA-joining enzyme" RELATED [EC:6.5.1.2] synonym: "poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming)" EXACT [EC:6.5.1.2] synonym: "Polydeoxyribonucleotide synthase (NAD(+)) activity" EXACT [EC:6.5.1.2] synonym: "polydeoxyribonucleotide synthase (NAD)" EXACT [EC:6.5.1.2] synonym: "polydeoxyribonucleotide synthase (NAD+) activity" EXACT [EC:6.5.1.2] synonym: "polynucleotide ligase" BROAD [EC:6.5.1.2] synonym: "polynucleotide ligase (NAD(+)) activity" EXACT [EC:6.5.1.2] synonym: "polynucleotide ligase (NAD)" EXACT [EC:6.5.1.2] synonym: "polynucleotide ligase (NAD+) activity" EXACT [EC:6.5.1.2] synonym: "polynucleotide ligase (nicotinamide adenine dinucleotide)" EXACT [EC:6.5.1.2] synonym: "polynucleotide synthetase (nicotinamide adenine dinucleotide)" EXACT [EC:6.5.1.2] synonym: "polynucleotide synthetase activity" EXACT [EC:6.5.1.2] xref: EC:6.5.1.2 xref: GO:0003911 xref: MetaCyc:DNA-LIGASE-(NAD(+))-RXN is_a: CCO:F0000413 ! DNA ligase activity [Term] id: CCO:F0000416 name: DNA nucleotidylexotransferase activity namespace: molecular_function def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)." [EC:2.7.7.31] synonym: "addase activity" EXACT [EC:2.7.7.31] synonym: "deoxynucleotidyl terminal transferase activity" EXACT [EC:2.7.7.31] synonym: "deoxyribonucleic acid nucleotidyltransferase activity" EXACT [EC:2.7.7.31] synonym: "deoxyribonucleic nucleotidyltransferase activity" EXACT [EC:2.7.7.31] synonym: "nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity" EXACT [EC:2.7.7.31] synonym: "TdT" RELATED [EC:2.7.7.31] synonym: "terminal addition enzyme activity" RELATED [EC:2.7.7.31] synonym: "terminal deoxynucleotide transferase activity" EXACT [EC:2.7.7.31] synonym: "terminal deoxynucleotidyltransferase activity" EXACT [EC:2.7.7.31] synonym: "terminal deoxyribonucleotidyltransferase activity" EXACT [EC:2.7.7.31] synonym: "terminal transferase activity" EXACT [EC:2.7.7.31] xref: EC:2.7.7.31 xref: GO:0003912 xref: MetaCyc:DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000417 name: DNA photolyase activity namespace: molecular_function def: "Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA." [GOC:mah, PMID:11124949] subset: gosubset_prok xref: EC:4.1.99.- xref: GO:0003913 is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0000418 name: DNA (6-4) photolyase activity namespace: molecular_function def: "Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA." [GOC:mah, PMID:11124949] xref: GO:0003914 is_a: CCO:F0000417 ! DNA photolyase activity [Term] id: CCO:F0000419 name: DNA topoisomerase activity namespace: molecular_function def: "Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA." [GOC:mah, PMID:8811192] subset: gosubset_prok xref: EC:5.99.1.- xref: GO:0003916 xref: GO:0009387 is_a: CCO:F0000274 ! DNA binding is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0000420 name: DNA topoisomerase type I activity namespace: molecular_function def: "Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle." [PMID:8811192] comment: Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity. subset: gosubset_prok synonym: "deoxyribonucleate topoisomerase" BROAD [EC:5.99.1.2] synonym: "DNA topoisomerase I activity" NARROW [] synonym: "nicking-closing enzyme activity" RELATED [EC:5.99.1.2] synonym: "omega-protein activity" RELATED [EC:5.99.1.2] synonym: "relaxing enzyme activity" RELATED [EC:5.99.1.2] synonym: "swivelase activity" RELATED [EC:5.99.1.2] synonym: "topoisomerase" BROAD [EC:5.99.1.2] synonym: "type I DNA topoisomerase activity" EXACT [] synonym: "type I topoisomerase activity" EXACT [] synonym: "untwisting enzyme activity" RELATED [EC:5.99.1.2] xref: EC:5.99.1.2 xref: GO:0003917 xref: MetaCyc:5.99.1.2-RXN is_a: CCO:F0000419 ! DNA topoisomerase activity [Term] id: CCO:F0000421 name: DNA topoisomerase (ATP-hydrolyzing) activity namespace: molecular_function def: "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192] subset: gosubset_prok synonym: "deoxyribonucleate topoisomerase" BROAD [EC:5.99.1.3] synonym: "deoxyribonucleic topoisomerase activity" EXACT [EC:5.99.1.3] synonym: "DNA gyrase activity" NARROW [] synonym: "DNA topoisomerase (ATP-hydrolysing)" BROAD [EC:5.99.1.3] synonym: "DNA topoisomerase II" RELATED [EC:5.99.1.3] synonym: "DNA topoisomerase IV activity" EXACT [] synonym: "DNA topoisomerase type II activity" EXACT [] synonym: "DNA-gyrase activity" EXACT [EC:5.99.1.3] synonym: "topoisomerase" BROAD [EC:5.99.1.3] synonym: "topoisomerase II" EXACT [] synonym: "type II DNA topoisomerase activity" EXACT [EC:5.99.1.3] xref: EC:5.99.1.3 xref: GO:0003918 xref: MetaCyc:5.99.1.3-RXN is_a: CCO:F0000419 ! DNA topoisomerase activity [Term] id: CCO:F0000422 name: FMN adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + FMN = diphosphate + FAD." [EC:2.7.7.2] subset: gosubset_prok synonym: "adenosine triphosphate-riboflavin mononucleotide transadenylase activity" EXACT [EC:2.7.7.2] synonym: "adenosine triphosphate-riboflavine mononucleotide transadenylase activity" EXACT [EC:2.7.7.2] synonym: "ATP:FMN adenylyltransferase activity" EXACT [] synonym: "FAD diphosphorylase activity" EXACT [EC:2.7.7.2] synonym: "FAD pyrophosphorylase activity" EXACT [EC:2.7.7.2] synonym: "FAD synthetase activity" EXACT [EC:2.7.7.2] synonym: "flavin adenine dinucleotide synthetase activity" EXACT [EC:2.7.7.2] synonym: "riboflavin adenine dinucleotide pyrophosphorylase activity" EXACT [EC:2.7.7.2] synonym: "riboflavin mononucleotide adenylyltransferase activity" EXACT [EC:2.7.7.2] synonym: "riboflavine adenine dinucleotide adenylyltransferase activity" EXACT [EC:2.7.7.2] xref: EC:2.7.7.2 xref: GO:0003919 xref: MetaCyc:FADSYN-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000423 name: GMP reductase activity namespace: molecular_function def: "Catalysis of the reaction: inosine 5'-phosphate + NH3 + NADP+ = guanosine 5'-phosphate + NADPH + H+." [EC:1.7.1.7] comment: Note that this function was formerly EC:1.6.6.8. subset: gosubset_prok synonym: "guanosine 5'-monophosphate oxidoreductase activity" EXACT [EC:1.7.1.7] synonym: "guanosine 5'-monophosphate reductase activity" EXACT [EC:1.7.1.7] synonym: "guanosine 5'-phosphate reductase activity" EXACT [EC:1.7.1.7] synonym: "guanosine monophosphate reductase activity" EXACT [EC:1.7.1.7] synonym: "guanylate reductase activity" RELATED [EC:1.7.1.7] synonym: "inosine-5'-phosphate:NADP+ oxidoreductase (aminating)" EXACT [EC:1.7.1.7] synonym: "NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating)" EXACT [EC:1.7.1.7] synonym: "NADPH:GMP oxidoreductase (deaminating) activity" EXACT [EC:1.7.1.7] synonym: "NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity" EXACT [EC:1.7.1.7] xref: EC:1.7.1.7 xref: GO:0003920 xref: MetaCyc:GMP-REDUCT-RXN is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0000424 name: GMP synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP." [EC:6.3.4.1] synonym: "guanylate synthetase activity" EXACT [EC:6.3.4.1] synonym: "xanthosine 5'-monophosphate aminase activity" EXACT [EC:6.3.4.1] synonym: "Xanthosine-5'-phosphate--ammonia ligase activity" EXACT [EC:6.3.4.1] synonym: "xanthosine-5'-phosphate-ammonia ligase activity" EXACT [EC:6.3.4.1] synonym: "xanthosine-5'-phosphate:ammonia ligase (AMP-forming)" EXACT [EC:6.3.4.1] synonym: "XMP aminase activity" EXACT [EC:6.3.4.1] xref: EC:6.3.4.1 xref: GO:0003921 xref: MetaCyc:GMP-SYN-NH3-RXN xref: Reactome:12506 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0000425 name: GMP synthase (glutamine-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + xanthosine 5'-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate." [EC:6.3.5.2] subset: gosubset_prok synonym: "glutamine amidotransferase activity" EXACT [EC:6.3.5.2] synonym: "GMP synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.2] synonym: "GMP synthetase (glutamine-hydrolysing)" EXACT [EC:6.3.5.2] synonym: "GMP synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.2] synonym: "guanosine 5'-monophosphate synthetase activity" EXACT [EC:6.3.5.2] synonym: "guanosine monophosphate synthetase (glutamine-hydrolyzing)" EXACT [EC:6.3.5.2] synonym: "guanylate synthetase (glutamine-hydrolyzing)" EXACT [EC:6.3.5.2] synonym: "xanthosine 5'-phosphate amidotransferase activity" EXACT [EC:6.3.5.2] synonym: "xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)" EXACT [EC:6.3.5.2] xref: EC:6.3.5.2 xref: GO:0003922 xref: MetaCyc:GMP-SYN-GLUT-RXN is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0000426 name: GPI-anchor transamidase activity namespace: molecular_function def: "Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor." [ISBN:0471331309 "Biochemical Pathways"] xref: EC:3.-.-.- xref: GO:0003923 xref: Reactome:12511 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0000427 name: GTPase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + H2O = GDP + phosphate." [ISBN:0198547684] comment: Consider also annotating to the molecular function term 'GTP binding ; GO:0005525'. subset: gosubset_prok synonym: "ARF small monomeric GTPase activity" NARROW [] synonym: "dynamin GTPase activity" NARROW [] synonym: "heterotrimeric G-protein GTPase activity" NARROW [] synonym: "heterotrimeric G-protein GTPase, alpha-subunit" RELATED [] synonym: "heterotrimeric G-protein GTPase, beta-subunit" RELATED [] synonym: "heterotrimeric G-protein GTPase, gamma-subunit" RELATED [] synonym: "hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement" BROAD [] synonym: "protein-synthesizing GTPase activity" NARROW [] synonym: "protein-synthesizing GTPase activity, elongation" NARROW [] synonym: "protein-synthesizing GTPase activity, initiation" NARROW [] synonym: "protein-synthesizing GTPase activity, termination" NARROW [] synonym: "Rab small monomeric GTPase activity" NARROW [] synonym: "Ran small monomeric GTPase activity" NARROW [] synonym: "Ras small monomeric GTPase activity" NARROW [] synonym: "RHEB small monomeric GTPase activity" NARROW [] synonym: "Rho small monomeric GTPase activity" NARROW [] synonym: "Sar small monomeric GTPase activity" NARROW [] synonym: "signal-recognition-particle GTPase activity" NARROW [] synonym: "small monomeric GTPase activity" NARROW [] synonym: "tubulin GTPase activity" NARROW [] xref: GO:0003924 xref: Reactome:12513 is_a: CCO:F0003574 ! nucleoside-triphosphatase activity [Term] id: CCO:F0000428 name: GTP cyclohydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized." [GOC:jl, http://cancerweb.ncl.ac.uk] subset: gosubset_prok xref: EC:3.5.4.- xref: GO:0003933 is_a: CCO:F0004139 ! cyclohydrolase activity [Term] id: CCO:F0000429 name: GTP cyclohydrolase I activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate." [EC:3.5.4.16] subset: gosubset_prok synonym: "dihydroneopterin triphosphate synthase activity" EXACT [EC:3.5.4.16] synonym: "GTP 7,8-8,9-dihydrolase activity" EXACT [EC:3.5.4.16] synonym: "GTP 8-formylhydrolase activity" EXACT [EC:3.5.4.16] synonym: "guanosine triphosphate 8-deformylase activity" EXACT [EC:3.5.4.16] synonym: "guanosine triphosphate cyclohydrolase activity" EXACT [EC:3.5.4.16] xref: EC:3.5.4.16 xref: GO:0003934 xref: MetaCyc:GTP-CYCLOHYDRO-I-RXN is_a: CCO:F0000428 ! GTP cyclohydrolase activity [Term] id: CCO:F0000430 name: GTP cyclohydrolase II activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 3 H2O = formate + 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + diphosphate." [EC:3.5.4.25] subset: gosubset_prok synonym: "GTP 7,8-8,9-dihydrolase (diphosphate-forming)" EXACT [EC:3.5.4.25] synonym: "GTP-8-formylhydrolase activity" EXACT [EC:3.5.4.25] synonym: "guanosine triphosphate cyclohydrolase II" RELATED [EC:3.5.4.25] xref: EC:3.5.4.25 xref: GO:0003935 xref: MetaCyc:GTP-CYCLOHYDRO-II-RXN is_a: CCO:F0000428 ! GTP cyclohydrolase activity [Term] id: CCO:F0000431 name: IMP cyclohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide." [EC:3.5.4.10] subset: gosubset_prok synonym: "IMP 1,2-hydrolase (decyclizing)" EXACT [EC:3.5.4.10] synonym: "IMP synthetase activity" EXACT [EC:3.5.4.10] synonym: "inosinate cyclohydrolase activity" EXACT [EC:3.5.4.10] synonym: "inosinicase activity" EXACT [EC:3.5.4.10] xref: EC:3.5.4.10 xref: GO:0003937 xref: MetaCyc:IMPCYCLOHYDROLASE-RXN xref: Reactome:12558 is_a: CCO:F0004139 ! cyclohydrolase activity [Term] id: CCO:F0000432 name: IMP dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+." [EC:1.1.1.205] subset: gosubset_prok synonym: "IMP oxidoreductase activity" EXACT [EC:1.1.1.205] synonym: "IMP:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.205] synonym: "inosinate dehydrogenase activity" RELATED [EC:1.1.1.205] synonym: "inosine 5'-monophosphate dehydrogenase activity" EXACT [EC:1.1.1.205] synonym: "inosine monophosphate dehydrogenase activity" EXACT [EC:1.1.1.205] synonym: "inosine monophosphate oxidoreductase activity" EXACT [EC:1.1.1.205] synonym: "inosine-5'-phosphate dehydrogenase activity" EXACT [EC:1.1.1.205] synonym: "inosinic acid dehydrogenase activity" RELATED [EC:1.1.1.205] xref: EC:1.1.1.205 xref: GO:0003938 xref: MetaCyc:IMP-DEHYDROG-RXN xref: Reactome:12563 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000433 name: L-iditol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+." [EC:1.1.1.14] comment: Note that enzymes with this activity also act on D-glucitol (giving D-fructose) and other closely related sugar alcohols. subset: gosubset_prok synonym: " L-iditol:NAD+ 5-oxidoreductase activity" EXACT [EC:1.1.1.14] synonym: "glucitol dehydrogenase activity" RELATED [EC:1.1.1.14] synonym: "L-iditol (sorbitol) dehydrogenase activity" RELATED [EC:1.1.1.14] synonym: "L-iditol:NAD oxidoreductase activity" EXACT [EC:1.1.1.14] synonym: "NAD+-dependent sorbitol dehydrogenase activity" RELATED [EC:1.1.1.14] synonym: "NAD-dependent sorbitol dehydrogenase activity" RELATED [EC:1.1.1.14] synonym: "NAD-sorbitol dehydrogenase" RELATED [EC:1.1.1.14] synonym: "polyol dehydrogenase activity" BROAD [EC:1.1.1.14] synonym: "sorbitol dehydrogenase activity" RELATED [EC:1.1.1.14] xref: EC:1.1.1.14 xref: GO:0003939 xref: MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000434 name: L-iduronidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in desulfated dermatan." [EC:3.2.1.76] synonym: "alpha-L-iduronidase activity" EXACT [EC:3.2.1.76] synonym: "glycosaminoglycan alpha-L-iduronohydrolase activity" EXACT [EC:3.2.1.76] xref: EC:3.2.1.76 xref: GO:0003940 xref: MetaCyc:3.2.1.76-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0000435 name: L-serine ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine = pyruvate + NH3." [EC:4.3.1.17] comment: Note that this function was formerly EC:4.3.1.13. subset: gosubset_prok synonym: "L-hydroxyaminoacid dehydratase activity" BROAD [] synonym: "L-serine ammonia-lyase (pyruvate-forming) activity" EXACT [EC:4.3.1.17] synonym: "L-serine deaminase activity" EXACT [] synonym: "L-serine dehydratase activity" BROAD [EC:4.3.1.17] synonym: "L-serine hydro-lyase (deaminating) activity" EXACT [] synonym: "serine deaminase activity" BROAD [EC:4.3.1.17] xref: EC:4.3.1.17 xref: GO:0003941 xref: MetaCyc:4.3.1.17-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0000436 name: N-acetyl-gamma-glutamyl-phosphate reductase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+." [EC:1.2.1.38] subset: gosubset_prok synonym: "N-acetyl-glutamate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.38] synonym: "N-acetyl-L-glutamate gamma-semialdehyde:NADP oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.38] synonym: "N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.38] synonym: "N-acetylglutamate 5-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.38] synonym: "N-acetylglutamic gamma-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.38] synonym: "NAGSA dehydrogenase activity" BROAD [EC:1.2.1.38] synonym: "reductase, acetyl-gamma-glutamyl phosphate" EXACT [EC:1.2.1.38] xref: EC:1.2.1.38 xref: GO:0003942 xref: MetaCyc:N-ACETYLGLUTPREDUCT-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000437 name: N-acetylgalactosamine-4-sulfatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate." [EC:3.1.6.12] subset: gosubset_prok synonym: "acetylgalactosamine 4-sulfatase activity" EXACT [EC:3.1.6.12] synonym: "arylsulfatase B" EXACT [] synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.12] synonym: "N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity" EXACT [EC:3.1.6.12] synonym: "N-acetylgalactosamine 4-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.12] synonym: "N-acetylgalactosamine-4-sulphatase activity" EXACT [] xref: EC:3.1.6.12 xref: GO:0003943 xref: MetaCyc:3.1.6.12-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0000438 name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity namespace: molecular_function def: "Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose." [EC:3.1.4.45] synonym: "2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity" EXACT [EC:3.1.4.45] synonym: "alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity" EXACT [EC:3.1.4.45] synonym: "alpha-N-acetylglucosaminyl phosphodiesterase activity" EXACT [EC:3.1.4.45] synonym: "glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity" EXACT [EC:3.1.4.45] synonym: "lysosomal alpha-N-acetylglucosaminidase activity" NARROW [EC:3.1.4.45] synonym: "phosphodiester glycosidase activity" EXACT [EC:3.1.4.45] xref: EC:3.1.4.45 xref: GO:0003944 xref: MetaCyc:3.1.4.45-RXN is_a: CCO:F0003024 ! hexosaminidase activity [Term] id: CCO:F0000439 name: N-acetyllactosamine synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine." [EC:2.4.1.90] subset: gosubset_prok synonym: "acetyllactosamine synthetase activity" EXACT [EC:2.4.1.90] synonym: "beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "beta-N-acetylglucosaminide beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "beta1-4GalT" RELATED [EC:2.4.1.90] synonym: "Gal-T" RELATED [EC:2.4.1.90] synonym: "lactosamine synthase activity" EXACT [EC:2.4.1.90] synonym: "lactosamine synthetase activity" EXACT [EC:2.4.1.90] synonym: "lactose synthetase A protein" RELATED [EC:2.4.1.90] synonym: "N-acetylglucosamine (beta-1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "N-acetylglucosamine (beta1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "N-acetyllactosamine synthetase activity" EXACT [EC:2.4.1.90] synonym: "NAL synthetase activity" EXACT [EC:2.4.1.90] synonym: "UDP-beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDP-Gal:N-acetylglucosamine beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDP-galactose-acetylglucosamine galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDP-galactose-N-acetylglucosamine galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity" EXACT [] synonym: "UDP-galactose:N-acetylglucosaminide beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDPgalactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "UDPgalactose:N-acetylglucosaminyl(beta1-4)galactosyltransferase activity" EXACT [EC:2.4.1.90] synonym: "uridine diphosphogalactose-acetylglucosamine galactosyltransferase activity" EXACT [EC:2.4.1.90] xref: EC:2.4.1.90 xref: GO:0003945 xref: MetaCyc:N-ACETYLLACTOSAMINE-SYNTHASE-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0000441 name: N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity namespace: molecular_function def: "Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-glucosaminylamine + L-aspartate." [EC:3.5.1.26] subset: gosubset_prok synonym: "4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.26] synonym: "aspartylglucosaminidase activity" EXACT [EC:3.5.1.26] synonym: "aspartylglucosylaminase activity" EXACT [EC:3.5.1.26] synonym: "aspartylglucosylamine deaspartylase activity" EXACT [EC:3.5.1.26] synonym: "aspartylglucosylaminidase activity" EXACT [EC:3.5.1.26] synonym: "aspartylglycosylamine amidohydrolase activity" EXACT [EC:3.5.1.26] synonym: "beta-aspartylglucosylamine amidohydrolase activity" EXACT [EC:3.5.1.26] synonym: "glucosylamidase activity" RELATED [EC:3.5.1.26] synonym: "glycosylasparaginase activity" EXACT [EC:3.5.1.26] synonym: "N-aspartyl-beta-glucosaminidase activity" EXACT [EC:3.5.1.26] synonym: "N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.26] xref: EC:3.5.1.26 xref: GO:0003948 xref: MetaCyc:3.5.1.26-RXN is_a: CCO:F0000542 ! asparaginase activity [Term] id: CCO:F0000442 name: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity namespace: molecular_function def: "Catalysis of the reaction: N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide = N-(5'-phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide." [EC:5.3.1.16] subset: gosubset_prok synonym: "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase activity" EXACT [EC:5.3.1.16] synonym: "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase activity" EXACT [EC:5.3.1.16] synonym: "N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase activity" EXACT [EC:5.3.1.16] synonym: "N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase activity" EXACT [EC:5.3.1.16] synonym: "phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase activity" EXACT [EC:5.3.1.16] synonym: "phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase activity" EXACT [EC:5.3.1.16] xref: EC:5.3.1.16 xref: GO:0003949 xref: MetaCyc:PRIBFAICARPISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0000443 name: NAD+ ADP-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor." [EC:2.4.2.30] subset: gosubset_prok synonym: "ADP-ribosyltransferase (polymerizing) activity" EXACT [EC:2.4.2.30] synonym: "NAD ADP-ribosyltransferase activity" EXACT [] synonym: "NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [EC:2.4.2.30] synonym: "poly(adenosine diphosphate ribose) polymerase activity" EXACT [EC:2.4.2.30] synonym: "poly(ADP-ribose) synthase activity" EXACT [EC:2.4.2.30] synonym: "poly(ADP-ribose) synthetase activity" EXACT [EC:2.4.2.30] synonym: "poly(ADP-ribose)polymerase activity" EXACT [EC:2.4.2.30] xref: EC:2.4.2.30 xref: GO:0003950 xref: MetaCyc:NAD(+)-ADP-RIBOSYLTRANSFERASE-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000444 name: NAD+ kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + NAD+ = ADP + NADP+." [EC:2.7.1.23] subset: gosubset_prok synonym: "ATP:NAD+ 2'-phosphotransferase activity" EXACT [EC:2.7.1.23] synonym: "DPN kinase activity" RELATED [EC:2.7.1.23] synonym: "NAD kinase activity" EXACT [] synonym: "NADK" RELATED [EC:2.7.1.23] synonym: "nicotinamide adenine dinucleotide kinase (phosphorylating)" EXACT [EC:2.7.1.23] synonym: "nicotinamide adenine dinucleotide kinase activity" EXACT [EC:2.7.1.23] xref: EC:2.7.1.23 xref: GO:0003951 xref: MetaCyc:NAD-KIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000445 name: NAD+ synthase (glutamine-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate." [EC:6.3.5.1] subset: gosubset_prok synonym: "deamido-NAD+:L-glutamine amido-ligase (AMP-forming)" EXACT [EC:6.3.5.1] synonym: "desamidonicotinamide adenine dinucleotide amidotransferase activity" EXACT [EC:6.3.5.1] synonym: "DPN synthetase activity" EXACT [EC:6.3.5.1] synonym: "NAD synthase (glutamine-hydrolyzing) activity" EXACT [] synonym: "NAD synthetase (glutamine-hydrolysing)" EXACT [EC:6.3.5.1] synonym: "NAD(+) synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.1] synonym: "NAD+ synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.1] synonym: "NAD+ synthetase (glutamine-hydrolyzing)" EXACT [EC:6.3.5.1] synonym: "nicotinamide adenine dinucleotide synthetase (glutamine) activity" EXACT [EC:6.3.5.1] xref: EC:6.3.5.1 xref: GO:0003952 xref: MetaCyc:NAD-SYNTH-GLN-RXN is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0000446 name: NAD+ nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose." [EC:3.2.2.5] subset: gosubset_prok synonym: "ADP-ribosyl cyclase activity" RELATED [EC:3.2.2.5] synonym: "diphosphopyridine nucleosidase activity" EXACT [EC:3.2.2.5] synonym: "DPN hydrolase activity" EXACT [EC:3.2.2.5] synonym: "DPNase activity" EXACT [EC:3.2.2.5] synonym: "NAD glycohydrolase activity" EXACT [EC:3.2.2.5] synonym: "NAD hydrolase activity" EXACT [EC:3.2.2.5] synonym: "NAD nucleosidase activity" EXACT [] synonym: "NAD+ glycohydrolase activity" EXACT [EC:3.2.2.5] synonym: "NADase activity" EXACT [EC:3.2.2.5] synonym: "nicotinamide adenine dinucleotide glycohydrolase activity" EXACT [EC:3.2.2.5] synonym: "nicotinamide adenine dinucleotide nucleosidase activity" EXACT [EC:3.2.2.5] xref: EC:3.2.2.5 xref: GO:0003953 xref: MetaCyc:NADNUCLEOSID-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0000447 name: NADH dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor." [EC:1.6.99.3] subset: gosubset_prok synonym: "beta-NADH dehydrogenase dinucleotide activity" EXACT [EC:1.6.99.3] synonym: "cytochrome c reductase activity" RELATED [EC:1.6.99.3] synonym: "diaphorase activity" BROAD [EC:1.6.99.3] synonym: "dihydrocodehydrogenase I dehydrogenase activity" EXACT [EC:1.6.99.3] synonym: "dihydronicotinamide adenine dinucleotide dehydrogenase activity" EXACT [EC:1.6.99.3] synonym: "diphosphopyridine diaphorase activity" EXACT [EC:1.6.99.3] synonym: "diphosphopyrinase activity" EXACT [EC:1.6.99.3] synonym: "DPNH diaphorase activity" EXACT [EC:1.6.99.3] synonym: "NADH diaphorase activity" EXACT [EC:1.6.99.3] synonym: "NADH hydrogenase activity" EXACT [EC:1.6.99.3] synonym: "NADH oxidoreductase activity" EXACT [EC:1.6.99.3] synonym: "NADH-menadione oxidoreductase activity" NARROW [EC:1.6.99.3] synonym: "NADH2 dehydrogenase activity" EXACT [EC:1.6.99.3] synonym: "NADH:(acceptor) oxidoreductase activity" EXACT [EC:1.6.99.3] synonym: "NADH:acceptor oxidoreductase activity" EXACT [EC:1.6.99.3] synonym: "NADH:cytochrome c oxidoreductase activity" NARROW [EC:1.6.99.3] synonym: "reduced diphosphopyridine nucleotide diaphorase activity" EXACT [EC:1.6.99.3] synonym: "type 1 dehydrogenase activity" RELATED [EC:1.6.99.3] synonym: "type I dehydrogenase activity" RELATED [EC:1.6.99.3] xref: EC:1.6.99.3 xref: GO:0003954 xref: MetaCyc:NADH-DEHYDROGENASE-RXN is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0000448 name: NAD(P)H dehydrogenase (quinone) activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)(+) + a hydroquinone." [EC:1.6.5.2] subset: gosubset_prok synonym: "azoreductase activity" BROAD [EC:1.6.5.2] synonym: "dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) activity" EXACT [EC:1.6.5.2] synonym: "diaphorase activity" BROAD [EC:1.6.5.2] synonym: "DT-diaphorase activity" EXACT [EC:1.6.5.2] synonym: "flavoprotein NAD(P)H-quinone reductase activity" EXACT [EC:1.6.5.2] synonym: "menadione oxidoreductase activity" NARROW [EC:1.6.5.2] synonym: "menadione reductase activity" NARROW [EC:1.6.5.2] synonym: "NAD(P)H dehydrogenase activity" EXACT [EC:1.6.5.2] synonym: "NAD(P)H menadione reductase activity" BROAD [EC:1.6.5.2] synonym: "NAD(P)H(2) dehydrogenase (quinone) activity" EXACT [EC:1.6.5.2] synonym: "NAD(P)H-quinone dehydrogenase activity" EXACT [EC:1.6.5.2] synonym: "NAD(P)H-quinone oxidoreductase activity" EXACT [EC:1.6.5.2] synonym: "NAD(P)H2 dehydrogenase (quinone)" EXACT [EC:1.6.5.2] synonym: "NAD(P)H: menadione oxidoreductase activity" BROAD [EC:1.6.5.2] synonym: "NAD(P)H:(quinone-acceptor)oxidoreductase activity" EXACT [EC:1.6.5.2] synonym: "NAD(P)H:quinone oxidoreductase activity" EXACT [EC:1.6.5.2] synonym: "NADH-menadione reductase activity" NARROW [EC:1.6.5.2] synonym: "naphthoquinone reductase activity" EXACT [EC:1.6.5.2] synonym: "Naphthoquinone reductase activity" NARROW [EC:1.6.5.2] synonym: "NQO1" RELATED [EC:1.6.5.2] synonym: "p-benzoquinone reductase activity" NARROW [EC:1.6.5.2] synonym: "phylloquinone reductase activity" NARROW [EC:1.6.5.2] synonym: "QR1" RELATED [EC:1.6.5.2] synonym: "quinone reductase activity" EXACT [EC:1.6.5.2] synonym: "reduced NAD(P)H dehydrogenase activity" EXACT [EC:1.6.5.2] synonym: "reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase activity" EXACT [EC:1.6.5.2] synonym: "viologen accepting pyridine nucleotide oxidoreductase activity" NARROW [EC:1.6.5.2] synonym: "vitamin K reductase activity" NARROW [EC:1.6.5.2] synonym: "vitamin-K reductase activity" NARROW [EC:1.6.5.2] xref: EC:1.6.5.2 xref: GO:0003955 xref: MetaCyc:NQOR-RXN xref: UM-BBD_enzymeID:e0202 is_a: CCO:F0003253 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [Term] id: CCO:F0000449 name: NAD(P)+-protein-arginine ADP-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine." [EC:2.4.2.31] synonym: "ADP-ribosyltransferase activity" BROAD [EC:2.4.2.31] synonym: "mono(ADP-ribosyl)transferase activity" BROAD [EC:2.4.2.31] synonym: "mono(ADPribosyl)transferase activity" BROAD [EC:2.4.2.31] synonym: "NAD(+):L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] synonym: "NAD(P)(+)--arginine ADP-ribosyltransferase activity" EXACT [EC:2.4.2.31] synonym: "NAD(P)+-arginine ADP-ribosyltransferase activity" EXACT [] synonym: "NAD(P)+:L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] synonym: "NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] synonym: "NAD(P)-arginine ADP-ribosyltransferase activity" EXACT [] synonym: "NAD+:L-arginine ADP-D-ribosyltransferase activity" EXACT [EC:2.4.2.31] synonym: "peptidyl-arginine ADP-ribosylation activity" EXACT [] synonym: "protein-arginine ADP-ribosyltransferase activity" EXACT [] xref: EC:2.4.2.31 xref: GO:0003956 xref: MetaCyc:2.4.2.31-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000450 name: NAD(P)+ transhydrogenase (B-specific) activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+." [EC:1.6.1.1, http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1991/113/i07/f-pdf/f_ja00007a002.pdf?sessid] subset: gosubset_prok synonym: "H+-thase" BROAD [EC:1.6.1.1] synonym: "NAD transhydrogenase" BROAD [EC:1.6.1.1] synonym: "NAD(P) transhydrogenase (B-specific) activity" EXACT [] synonym: "NADH transhydrogenase" BROAD [EC:1.6.1.1] synonym: "NADH-NADP-transhydrogenase" BROAD [EC:1.6.1.1] synonym: "NADPH-NAD oxidoreductase" BROAD [EC:1.6.1.1] synonym: "NADPH-NAD transhydrogenase" BROAD [EC:1.6.1.1] synonym: "NADPH:NAD+ oxidoreductase (B-specific)" EXACT [EC:1.6.1.1] synonym: "NADPH:NAD+ transhydrogenase" BROAD [EC:1.6.1.1] synonym: "nicotinamide adenine dinucleotide (phosphate) transhydrogenase" BROAD [EC:1.6.1.1] synonym: "nicotinamide nucleotide transhydrogenase activity" BROAD [EC:1.6.1.1] synonym: "non-energy-linked transhydrogenase activity" EXACT [EC:1.6.1.1] synonym: "pyridine nucleotide transferase" BROAD [EC:1.6.1.1] synonym: "pyridine nucleotide transhydrogenase activity" BROAD [EC:1.6.1.1] xref: EC:1.6.1.1 xref: GO:0003957 xref: MetaCyc:PYRNUTRANSHYDROGEN-RXN is_a: CCO:F0002094 ! NAD(P) transhydrogenase activity is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity [Term] id: CCO:F0000451 name: NADPH-hemoprotein reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein." [EC:1.6.2.4] subset: gosubset_prok synonym: "aldehyde reductase (NADPH-dependent) activity" RELATED [EC:1.6.2.4] synonym: "CPR activity" RELATED [EC:1.6.2.4] synonym: "cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity" NARROW [EC:1.6.2.4] synonym: "cytochrome P-450 reductase activity" EXACT [EC:1.6.2.4] synonym: "cytochrome P450 reductase activity" NARROW [EC:1.6.2.4] synonym: "dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity" NARROW [EC:1.6.2.4] synonym: "FAD-cytochrome c reductase activity" RELATED [EC:1.6.2.4] synonym: "ferrihemoprotein P-450 reductase activity" RELATED [EC:1.6.2.4] synonym: "NADP--cytochrome c reductase activity" NARROW [EC:1.6.2.4] synonym: "NADP--cytochrome reductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH--cytochrome c oxidoreductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH--cytochrome c reductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH--cytochrome P450 oxidoreductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH--cytochrome P450 reductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH--ferricytochrome c oxidoreductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH--ferrihemoprotein reductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH-cytochrome P-450 oxidoreductase activity" EXACT [EC:1.6.2.4] synonym: "NADPH-cytochrome p-450 reductase activity" EXACT [EC:1.6.2.4] synonym: "NADPH-dependent cytochrome c reductase activity" NARROW [EC:1.6.2.4] synonym: "NADPH-ferrihemoprotein reductase activity" EXACT [] synonym: "NADPH:cytochrome c reductase activity" EXACT [] synonym: "NADPH:cytochrome P450 reductase activity" EXACT [] synonym: "NADPH:ferrihemoprotein oxidoreductase activity" EXACT [EC:1.6.2.4] synonym: "NADPH:hemoprotein oxidoreductase activity" EXACT [EC:1.6.2.4] synonym: "NADPH:P-450 reductase activity" EXACT [EC:1.6.2.4] synonym: "NADPH:P450 reductase activity" NARROW [EC:1.6.2.4] synonym: "POR" RELATED [EC:1.6.2.4] synonym: "reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity" NARROW [EC:1.6.2.4] synonym: "reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity" NARROW [EC:1.6.2.4] synonym: "TPNH(2) cytochrome c reductase activity" NARROW [EC:1.6.2.4] synonym: "TPNH-cytochrome c reductase activity" NARROW [EC:1.6.2.4] synonym: "TPNH2 cytochrome c reductase activity" EXACT [EC:1.6.2.4] xref: EC:1.6.2.4 xref: GO:0003958 xref: MetaCyc:NADPH--FERRIHEMOPROTEIN-REDUCTASE-RXN is_a: CCO:F0003251 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor [Term] id: CCO:F0000452 name: NADPH dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + quinone acceptor = NADP+ + hydroquinone." [EC:1.6.99.1] subset: gosubset_prok synonym: "dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity" EXACT [EC:1.6.99.1] synonym: "NADPH diaphorase activity" EXACT [EC:1.6.99.1] synonym: "NADPH-dehydrogenase activity" EXACT [EC:1.6.99.1] synonym: "NADPH2 diaphorase activity" EXACT [EC:1.6.99.1] synonym: "NADPH2-dehydrogenase activity" EXACT [EC:1.6.99.1] synonym: "NADPH:(acceptor) oxidoreductase activity" EXACT [EC:1.6.99.1] synonym: "NADPH:acceptor oxidoreductase activity" EXACT [EC:1.6.99.1] synonym: "old yellow enzyme" RELATED [EC:1.6.99.1] synonym: "OYE" RELATED [EC:1.6.99.1] synonym: "reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity" EXACT [EC:1.6.99.1] synonym: "TPNH dehydrogenase activity" EXACT [EC:1.6.99.1] synonym: "TPNH-diaphorase activity" EXACT [EC:1.6.99.1] synonym: "triphosphopyridine diaphorase activity" EXACT [EC:1.6.99.1] synonym: "triphosphopyridine nucleotide diaphorase activity" EXACT [EC:1.6.99.1] xref: EC:1.6.99.1 xref: GO:0003959 xref: GO:0008468 xref: GO:0016660 xref: MetaCyc:NADPH-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0523 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0000453 name: NADPH:quinone reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone." [EC:1.6.5.5] subset: gosubset_prok synonym: "NADPH:quinone oxidoreductase activity" EXACT [EC:1.6.5.5] synonym: "quinone oxidoreductase activity" BROAD [EC:1.6.5.5] synonym: "zeta-crystallin activity" NARROW [EC:1.6.5.5] xref: EC:1.6.5.5 xref: GO:0003960 xref: MetaCyc:QOR-RXN is_a: CCO:F0003253 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [Term] id: CCO:F0000454 name: O-acetylhomoserine aminocarboxypropyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate." [EC:2.5.1.49] comment: Note that this function was formerly EC:4.2.99.10. subset: gosubset_prok synonym: "4.2.99.9" RELATED [] synonym: "O-acetyl-L-homoserine acetate-lyase (adding methanethiol) activity" EXACT [EC:2.5.1.49] synonym: "O-acetyl-L-homoserine sulfhydrolase activity" EXACT [EC:2.5.1.49] synonym: "O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity" EXACT [EC:2.5.1.49] synonym: "O-acetylhomoserine (thiol)-lyase activity" EXACT [] synonym: "O-acetylhomoserine sulfhydrolase activity" EXACT [EC:2.5.1.49] synonym: "OAH sulfhydrylase activity" EXACT [EC:2.5.1.49] xref: EC:2.5.1.49 xref: GO:0003961 xref: MetaCyc:O-ACETYLHOMOSERINE-(THIOL)-LYASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000455 name: cystathionine gamma-synthase activity namespace: molecular_function def: "Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate." [EC:2.5.1.48] comment: Formerly EC 4.2.99.9. subset: gosubset_prok synonym: "CTT gamma synthase activity" EXACT [] synonym: "cystathionine g-synthase activity" EXACT [] synonym: "cystathionine gamma synthase activity" EXACT [] synonym: "cystathionine synthase activity" EXACT [EC:2.5.1.48] synonym: "cystathionine synthetase activity" EXACT [EC:2.5.1.48] synonym: "homoserine O-transsuccinylase activity" BROAD [EC:2.5.1.48] synonym: "homoserine transsuccinylase activity" BROAD [EC:2.5.1.48] synonym: "O-succinyl-L-homoserine (thiol)-lyase activity" EXACT [] synonym: "O-succinyl-L-homoserine succinate-lyase (adding cysteine) activity" EXACT [EC:2.5.1.48] synonym: "O-succinyl-L-homoserine succinate-lyase activity" EXACT [] synonym: "O-succinylhomoserine (thiol)-lyase activity" EXACT [EC:2.5.1.48] synonym: "O-succinylhomoserine synthase activity" EXACT [EC:2.5.1.48] synonym: "O-succinylhomoserine synthetase activity" EXACT [EC:2.5.1.48] synonym: "O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase activity" EXACT [EC:2.5.1.48] xref: EC:2.5.1.48 xref: GO:0000505 xref: GO:0003962 xref: MetaCyc:O-SUCCHOMOSERLYASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000456 name: RNA-3'-phosphate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate." [EC:6.5.1.4] subset: gosubset_prok synonym: "RNA 3'-terminal phosphate cyclase activity" EXACT [EC:6.5.1.4] synonym: "RNA cyclase activity" EXACT [EC:6.5.1.4] synonym: "RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)" EXACT [EC:6.5.1.4] xref: EC:6.5.1.4 xref: GO:0003963 xref: MetaCyc:RNA-3 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003444 ! ligase activity, forming phosphoric ester bonds [Term] id: CCO:F0000457 name: RNA-directed DNA polymerase activity namespace: molecular_function def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time." [EC:2.7.7.49] subset: gosubset_prok synonym: "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity" EXACT [EC:2.7.7.49] synonym: "DNA nucleotidyltransferase (RNA-directed) activity" EXACT [EC:2.7.7.49] synonym: "reverse transcriptase activity" EXACT [EC:2.7.7.49] synonym: "revertase activity" RELATED [EC:2.7.7.49] synonym: "RNA revertase activity" EXACT [EC:2.7.7.49] synonym: "RNA-dependent deoxyribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.49] synonym: "RNA-dependent DNA polymerase activity" EXACT [EC:2.7.7.49] synonym: "RNA-directed DNA polymerase, group II intron encoded" NARROW [] synonym: "RNA-directed DNA polymerase, transposon encoded" NARROW [] synonym: "RNA-instructed DNA polymerase activity" EXACT [EC:2.7.7.49] synonym: "RT" RELATED [EC:2.7.7.49] xref: EC:2.7.7.49 xref: GO:0003964 xref: MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN xref: Reactome:10568 is_a: CCO:F0005510 ! DNA polymerase activity [Term] id: CCO:F0000458 name: RNA-directed RNA polymerase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside triphosphate + RNA (n) = diphosphate + RNA (n+1); uses an RNA template." [EC:2.7.7.48, GOC:mah] subset: gosubset_prok synonym: "3D polymerase activity" EXACT [EC:2.7.7.48] synonym: "nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [EC:2.7.7.48] synonym: "PB1 proteins" RELATED [EC:2.7.7.48] synonym: "PB2 proteins" RELATED [EC:2.7.7.48] synonym: "phage f2 replicase" NARROW [EC:2.7.7.48] synonym: "polymerase L" RELATED [EC:2.7.7.48] synonym: "Q-beta replicase activity" EXACT [EC:2.7.7.48] synonym: "RDRP" RELATED [EC:2.7.7.48] synonym: "ribonucleic acid replicase activity" EXACT [EC:2.7.7.48] synonym: "ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.48] synonym: "ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [EC:2.7.7.48] synonym: "ribonucleic replicase activity" EXACT [EC:2.7.7.48] synonym: "ribonucleic synthetase activity" RELATED [EC:2.7.7.48] synonym: "RNA nucleotidyltransferase (RNA-directed) activity" EXACT [EC:2.7.7.48] synonym: "RNA replicase activity" EXACT [EC:2.7.7.48] synonym: "RNA synthetase activity" RELATED [EC:2.7.7.48] synonym: "RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.48] synonym: "RNA-dependent RNA polymerase activity" EXACT [EC:2.7.7.48] synonym: "RNA-dependent RNA replicase activity" EXACT [EC:2.7.7.48] synonym: "transcriptase" BROAD [EC:2.7.7.48] xref: EC:2.7.7.48 xref: GO:0003968 xref: MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN xref: Reactome:12642 is_a: CCO:F0005511 ! RNA polymerase activity [Term] id: CCO:F0000459 name: RNA ligase (ATP) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + ribonucleotide (n) + ribonucleotide (m) = AMP + diphosphate + ribonucleotide (n+m)." [EC:6.5.1.3] subset: gosubset_prok synonym: "poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)" EXACT [EC:6.5.1.3] synonym: "polyribonucleotide ligase activity" EXACT [EC:6.5.1.3] synonym: "polyribonucleotide synthase (ATP) activity" EXACT [EC:6.5.1.3] synonym: "ribonucleic ligase activity" BROAD [EC:6.5.1.3] xref: EC:6.5.1.3 xref: GO:0003972 xref: MetaCyc:RNA-LIGASE-(ATP)-RXN is_a: CCO:F0001915 ! RNA ligase activity [Term] id: CCO:F0000461 name: UDP-N-acetylglucosamine 4-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine." [EC:5.1.3.7] subset: gosubset_prok synonym: "UDP acetylglucosamine epimerase activity" EXACT [EC:5.1.3.7] synonym: "UDP-GlcNAc 4-epimerase activity" EXACT [EC:5.1.3.7] synonym: "UDP-N-acetyl-D-glucosamine 4-epimerase activity" EXACT [EC:5.1.3.7] synonym: "uridine 5'-diphospho-N-acetylglucosamine-4-epimerase activity" EXACT [EC:5.1.3.7] synonym: "uridine diphosphate N-acetylglucosamine-4-epimerase activity" EXACT [EC:5.1.3.7] synonym: "uridine diphosphoacetylglucosamine epimerase activity" EXACT [EC:5.1.3.7] xref: EC:5.1.3.7 xref: GO:0003974 xref: MetaCyc:UDP-N-ACETYLGLUCOSAMINE-4-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0000462 name: UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol." [EC:2.7.8.15] subset: gosubset_prok synonym: "chitobiosylpyrophosphoryldolichol synthase activity" EXACT [EC:2.7.8.15] synonym: "dolichol phosphate N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.15] synonym: "GlcNAc-1-P transferase activity" EXACT [EC:2.7.8.15] synonym: "N-acetylglucosamine-1-phosphate transferase activity" EXACT [EC:2.7.8.15] synonym: "UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase activity" EXACT [EC:2.7.8.15] synonym: "UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.15] synonym: "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity" EXACT [EC:2.7.8.15] synonym: "UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase activity" EXACT [EC:2.7.8.15] synonym: "UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase activity" EXACT [EC:2.7.8.15] synonym: "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase activity" EXACT [EC:2.7.8.15] synonym: "UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity" EXACT [] synonym: "uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.15] xref: EC:2.7.8.15 xref: GO:0003975 xref: MetaCyc:2.7.8.15-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0000463 name: UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose." [EC:2.7.8.17] synonym: "lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] synonym: "N-acetylglucosaminyl phosphotransferase activity" EXACT [EC:2.7.8.17] synonym: "N-acetylglucosaminylphosphotransferase activity" RELATED [EC:2.7.8.17] synonym: "UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] synonym: "UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase activity" EXACT [EC:2.7.8.17] synonym: "UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] synonym: "UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase activity" EXACT [EC:2.7.8.17] synonym: "UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase activity" EXACT [EC:2.7.8.17] xref: EC:2.7.8.17 xref: GO:0003976 xref: MetaCyc:2.7.8.17-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0000464 name: UDP-N-acetylglucosamine diphosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine." [EC:2.7.7.23] subset: gosubset_prok synonym: "acetylglucosamine 1-phosphate uridylyltransferase" BROAD [EC:2.7.7.23] synonym: "GlmU uridylyltransferase activity" EXACT [EC:2.7.7.23] synonym: "N-acetylglucosamine-1-phosphate uridyltransferase activity" EXACT [EC:2.7.7.23] synonym: "UDP-acetylglucosamine pyrophosphorylase activity" EXACT [EC:2.7.7.23] synonym: "UDP-GlcNAc pyrophosphorylase activity" EXACT [EC:2.7.7.23] synonym: "UDP-N-acetylglucosamine pyrophosphorylase activity" EXACT [] synonym: "uridine diphosphate-N-acetylglucosamine pyrophosphorylase activity" EXACT [EC:2.7.7.23] synonym: "uridine diphosphoacetylglucosamine phosphorylase activity" EXACT [EC:2.7.7.23] synonym: "uridine diphosphoacetylglucosamine pyrophosphorylase activity" EXACT [EC:2.7.7.23] synonym: "UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.23] synonym: "UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.23] xref: EC:2.7.7.23 xref: GO:0003977 xref: MetaCyc:NAG1P-URIDYLTRANS-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000465 name: UDP-glucose 4-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose = UDP-galactose." [EC:5.1.3.2] subset: gosubset_prok synonym: "4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "galactowaldenase activity" RELATED [EC:5.1.3.2] synonym: "UDP-D-galactose 4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "UDP-galactose 4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "UDP-glucose epimerase activity" EXACT [EC:5.1.3.2] synonym: "UDPG-4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "UDPgalactose 4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "UDPglucose 4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "uridine diphosphate galactose 4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "uridine diphosphate glucose 4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "uridine diphospho-galactose-4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "uridine diphosphoglucose 4-epimerase activity" EXACT [EC:5.1.3.2] synonym: "uridine diphosphoglucose epimerase activity" EXACT [EC:5.1.3.2] xref: EC:5.1.3.2 xref: GO:0003978 xref: MetaCyc:UDPGLUCEPIM-RXN xref: Reactome:12673 is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0000466 name: UDP-glucose 6-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH + H+." [EC:1.1.1.22] subset: gosubset_prok xref: EC:1.1.1.22 xref: GO:0003979 xref: MetaCyc:UGD-RXN xref: Reactome:12674 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000467 name: UDP-glucose:glycoprotein glucosyltransferase activity namespace: molecular_function def: "Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins." [PMID:10764828] synonym: "UGGT activity" EXACT [] xref: EC:2.4.1.- xref: GO:0003980 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0000468 name: UTP:glucose-1-phosphate uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose." [EC:2.7.7.9] subset: gosubset_prok synonym: "glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.9] synonym: "UDP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] synonym: "UDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.9] synonym: "UDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] synonym: "UDPG phosphorylase activity" EXACT [EC:2.7.7.9] synonym: "UDPG pyrophosphorylase activity" EXACT [EC:2.7.7.9] synonym: "uridine 5'-diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] synonym: "uridine diphosphate-D-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] synonym: "uridine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] synonym: "uridine-diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.9] synonym: "UTP-glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.9] synonym: "UTP:alpha-D-glucose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.9] xref: EC:2.7.7.9 xref: GO:0003983 xref: MetaCyc:GLUC1PURIDYLTRANS-RXN xref: Reactome:12708 is_a: CCO:F0008184 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity [Term] id: CCO:F0000469 name: acetolactate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2." [EC:2.2.1.6] comment: Note that this function was formerly EC:4.1.3.18. subset: gosubset_prok synonym: "acetohydroxy acid synthetase activity" EXACT [EC:2.2.1.6] synonym: "acetohydroxyacid synthase activity" EXACT [EC:2.2.1.6] synonym: "acetolactate pyruvate-lyase (carboxylating) activity" EXACT [EC:2.2.1.6] synonym: "acetolactic synthetase activity" EXACT [EC:2.2.1.6] synonym: "alpha-acetohydroxy acid synthetase activity" EXACT [EC:2.2.1.6] synonym: "alpha-acetohydroxyacid synthase activity" EXACT [EC:2.2.1.6] synonym: "alpha-acetolactate synthase activity" EXACT [EC:2.2.1.6] synonym: "alpha-acetolactate synthetase activity" EXACT [EC:2.2.1.6] synonym: "pyruvate:pyruvate acetaldehydetransferase (decarboxylating)" EXACT [EC:2.2.1.6] xref: EC:2.2.1.6 xref: GO:0003984 xref: MetaCyc:ACETOLACTSYN-RXN is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0000470 name: acetyl-CoA C-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA." [EC:2.3.1.9] subset: gosubset_prok synonym: "2-methylacetoacetyl-CoA thiolase" BROAD [EC:2.3.1.9] synonym: "3-oxothiolase activity" EXACT [EC:2.3.1.9] synonym: "acetoacetyl-CoA thiolase activity" EXACT [EC:2.3.1.9] synonym: "acetyl coenzyme A thiolase activity" EXACT [EC:2.3.1.9] synonym: "acetyl-CoA acetyltransferase activity" EXACT [EC:2.3.1.9] synonym: "acetyl-CoA:acetyl-CoA C-acetyltransferase activity" EXACT [EC:2.3.1.9] synonym: "acetyl-CoA:N-acetyltransferase activity" EXACT [EC:2.3.1.9] synonym: "beta-acetoacetyl coenzyme A thiolase activity" EXACT [EC:2.3.1.9] synonym: "thiolase II" RELATED [EC:2.3.1.9] xref: EC:2.3.1.9 xref: GO:0003985 xref: MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN xref: UM-BBD_enzymeID:e0144 is_a: CCO:F0003163 ! C-acetyltransferase activity [Term] id: CCO:F0000471 name: acetyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + H2O = CoA + acetate." [EC:3.1.2.1] subset: gosubset_prok synonym: "acetyl coenzyme A acylase activity" EXACT [EC:3.1.2.1] synonym: "acetyl coenzyme A deacylase activity" EXACT [EC:3.1.2.1] synonym: "acetyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.1] synonym: "acetyl-CoA acylase activity" EXACT [EC:3.1.2.1] synonym: "acetyl-CoA deacylase activity" EXACT [EC:3.1.2.1] synonym: "acetyl-CoA thiol esterase activity" EXACT [EC:3.1.2.1] xref: EC:3.1.2.1 xref: GO:0003986 xref: MetaCyc:ACETYL-COA-HYDROLASE-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0000472 name: acetate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA." [EC:6.2.1.1] subset: gosubset_prok synonym: "acetate thiokinase activity" BROAD [EC:6.2.1.1] synonym: "acetate to acetyl-CoA" RELATED [] synonym: "acetate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.1] synonym: "acetic thiokinase activity" EXACT [EC:6.2.1.1] synonym: "acetyl activating enzyme" RELATED [EC:6.2.1.1] synonym: "acetyl CoA ligase activity" EXACT [EC:6.2.1.1] synonym: "acetyl CoA synthase activity" EXACT [EC:6.2.1.1] synonym: "acetyl coenzyme A synthetase activity" EXACT [EC:6.2.1.1] synonym: "acetyl-activating enzyme activity" EXACT [EC:6.2.1.1] synonym: "acetyl-CoA synthase activity" EXACT [EC:6.2.1.1] synonym: "acetyl-CoA synthetase activity" EXACT [EC:6.2.1.1] synonym: "acetyl-coenzyme A synthase activity" EXACT [EC:6.2.1.1] synonym: "ACS" RELATED [EC:6.2.1.1] synonym: "acyl-activating enzyme activity" BROAD [EC:6.2.1.1] synonym: "short chain fatty acyl-CoA synthetase activity" EXACT [EC:6.2.1.1] synonym: "short-chain acyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.1] xref: EC:6.2.1.1 xref: GO:0003987 xref: MetaCyc:ACETATE--COA-LIGASE-RXN xref: Reactome:12714 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0000473 name: acetyl-CoA C-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA." [EC:2.3.1.16] subset: gosubset_prok synonym: "2-keto-acyl thiolase activity" EXACT [] synonym: "2-methylacetoacetyl-CoA thiolase" BROAD [EC:2.3.1.16] synonym: "3-ketoacyl CoA thiolase activity" EXACT [EC:2.3.1.16] synonym: "3-ketoacyl coenzyme A thiolase activity" EXACT [EC:2.3.1.16] synonym: "3-ketoacyl thiolase activity" EXACT [EC:2.3.1.16] synonym: "3-ketoacyl-CoA thiolase activity" EXACT [] synonym: "3-ketothiolase activity" EXACT [EC:2.3.1.16] synonym: "3-oxoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] synonym: "3-oxoacyl-coenzyme A thiolase activity" EXACT [EC:2.3.1.16] synonym: "6-oxoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] synonym: "acetoacetyl-CoA beta-ketothiolase activity" EXACT [EC:2.3.1.16] synonym: "acetyl-CoA acyltransferase activity" EXACT [EC:2.3.1.16] synonym: "acyl-CoA:acetyl-CoA C-acyltransferase activity" EXACT [EC:2.3.1.16] synonym: "beta-ketoacyl coenzyme A thiolase activity" EXACT [EC:2.3.1.16] synonym: "beta-ketoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] synonym: "beta-ketoadipyl coenzyme A thiolase activity" EXACT [EC:2.3.1.16] synonym: "beta-ketoadipyl-CoA thiolase activity" EXACT [EC:2.3.1.16] synonym: "beta-ketothiolase activity" EXACT [EC:2.3.1.16] synonym: "KAT" RELATED [EC:2.3.1.16] synonym: "ketoacyl-CoA acyltransferase activity" EXACT [EC:2.3.1.16] synonym: "ketoacyl-coenzyme A thiolase activity" EXACT [EC:2.3.1.16] synonym: "long-chain 3-oxoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] synonym: "oxoacyl-coenzyme A thiolase activity" EXACT [EC:2.3.1.16] synonym: "pro-3-ketoacyl-CoA thiolase activity" EXACT [EC:2.3.1.16] synonym: "thiolase I" RELATED [EC:2.3.1.16] xref: EC:2.3.1.16 xref: GO:0003988 xref: MetaCyc:KETOACYLCOATHIOL-RXN xref: UM-BBD_enzymeID:e0653 is_a: CCO:F0003131 ! C-acyltransferase activity [Term] id: CCO:F0000474 name: acetyl-CoA carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA." [EC:6.4.1.2] subset: gosubset_prok synonym: "acetyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.2] synonym: "acetyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.2] xref: EC:6.4.1.2 xref: GO:0003989 xref: MetaCyc:ACETYL-COA-CARBOXYLTRANSFER-RXN xref: Reactome:12716 is_a: CCO:F0003144 ! CoA carboxylase activity [Term] id: CCO:F0000475 name: acetylcholinesterase activity namespace: molecular_function def: "Catalysis of the reaction: acetylcholine + H2O = choline + acetate." [EC:3.1.1.7] subset: gosubset_prok synonym: "AcCholE" RELATED [EC:3.1.1.7] synonym: "acetyl.beta-methylcholinesterase activity" EXACT [EC:3.1.1.7] synonym: "acetylcholine acetylhydrolase activity" EXACT [EC:3.1.1.7] synonym: "acetylcholine hydrolase activity" EXACT [EC:3.1.1.7] synonym: "acetylthiocholinesterase activity" EXACT [EC:3.1.1.7] synonym: "choline esterase I activity" EXACT [EC:3.1.1.7] synonym: "true cholinesterase activity" EXACT [EC:3.1.1.7] xref: EC:3.1.1.7 xref: GO:0003990 xref: MetaCyc:ACETYLCHOLINESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0000476 name: acetylglutamate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate." [EC:2.7.2.8] subset: gosubset_prok synonym: "acetylglutamate phosphokinase activity" EXACT [EC:2.7.2.8] synonym: "ATP:N-acetyl-L-glutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.8] synonym: "N-acetylglutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.8] synonym: "N-acetylglutamate kinase activity" EXACT [EC:2.7.2.8] synonym: "N-acetylglutamate phosphokinase activity" EXACT [EC:2.7.2.8] synonym: "N-acetylglutamic 5-phosphotransferase activity" EXACT [EC:2.7.2.8] xref: EC:2.7.2.8 xref: GO:0003991 xref: MetaCyc:ACETYLGLUTKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0000477 name: acetylornithine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: N2-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate." [EC:2.6.1.11] subset: gosubset_prok synonym: "2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity" EXACT [EC:2.6.1.11] synonym: "acetylornithine 5-aminotransferase activity" EXACT [EC:2.6.1.11] synonym: "acetylornithine aminotransferase activity" EXACT [] synonym: "acetylornithine delta-transaminase activity" EXACT [EC:2.6.1.11] synonym: "ACOAT activity" EXACT [EC:2.6.1.11] synonym: "N(2)-acetylornithine 5-transaminase activity" EXACT [EC:2.6.1.11] synonym: "N-acetylornithine aminotransferase activity" EXACT [EC:2.6.1.11] synonym: "N-acetylornithine-delta-transaminase activity" EXACT [EC:2.6.1.11] synonym: "N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity" EXACT [EC:2.6.1.11] synonym: "N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.11] synonym: "N2-acetylornithine 5-aminotransferase activity" EXACT [] synonym: "N2-acetylornithine 5-transaminase activity" EXACT [EC:2.6.1.11] synonym: "succinylornithine aminotransferase activity" BROAD [EC:2.6.1.11] xref: EC:2.6.1.11 xref: GO:0003992 xref: GO:0047318 xref: MetaCyc:ACETYLORNTRANSAM-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000478 name: acid phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum." [EC:3.1.3.2] subset: gosubset_prok synonym: "acid monophosphatase activity" EXACT [EC:3.1.3.2] synonym: "acid nucleoside diphosphate phosphatase activity" EXACT [EC:3.1.3.2] synonym: "acid phosphohydrolase activity" EXACT [EC:3.1.3.2] synonym: "acid phosphomonoester hydrolase activity" EXACT [EC:3.1.3.2] synonym: "acid phosphomonoesterase activity" EXACT [EC:3.1.3.2] synonym: "glycerophosphatase activity" BROAD [EC:3.1.3.2] synonym: "orthophosphoric-monoester phosphohydrolase (acid optimum)" EXACT [EC:3.1.3.2] synonym: "phosphate-monoester phosphohydrolase (acid optimum)" EXACT [EC:3.1.3.2] synonym: "phosphomonoesterase activity" BROAD [EC:3.1.3.2] synonym: "uteroferrin" RELATED [EC:3.1.3.2] xref: EC:3.1.3.2 xref: GO:0003993 xref: MetaCyc:ACID-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000479 name: aconitate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: citrate = cis-aconitate + H2O = isocitrate; i.e. the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate." [EC:4.2.1.3] subset: gosubset_prok synonym: "aconitase activity" EXACT [] synonym: "cis-aconitase activity" EXACT [EC:4.2.1.3] synonym: "citrate hydro-lyase activity" BROAD [EC:4.2.1.3] synonym: "citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [EC:4.2.1.3] synonym: "citrate(isocitrate) hydro-lyase activity" EXACT [EC:4.2.1.3] xref: EC:4.2.1.3 xref: GO:0003994 xref: MetaCyc:ACONITATEDEHYDR-RXN xref: Reactome:12740 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000480 name: acyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor." [EC:1.3.99.3] subset: gosubset_prok synonym: "acyl CoA dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "acyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "acyl dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "acyl-CoA:(acceptor) 2,3-oxidoreductase activity" EXACT [EC:1.3.99.3] synonym: "acyl-CoA:acceptor 2,3-oxidoreductase activity" EXACT [EC:1.3.99.3] synonym: "fatty acyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "fatty-acyl-CoA dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "general acyl CoA dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "long-chain acyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "long-chain acyl-CoA dehydrogenase activity" EXACT [EC:1.3.99.3] synonym: "medium-chain acyl-CoA dehydrogenase activity" NARROW [EC:1.3.99.3] synonym: "medium-chain acyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.3] xref: EC:1.3.99.3 xref: GO:0003995 xref: MetaCyc:ACYLCOADEHYDROG-RXN xref: Reactome:4266 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0000481 name: acyl-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: an acyl + ATP + CoASH = AMP + diphosphate + acyl-CoA." [GOC:mah] subset: gosubset_prok xref: EC:6.2.1.- xref: GO:0003996 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0000482 name: acyl-CoA oxidase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2." [EC:1.3.3.6] subset: gosubset_prok synonym: "acyl coenzyme A oxidase activity" EXACT [EC:1.3.3.6] synonym: "acyl-CoA:oxygen 2-oxidoreductase activity" EXACT [EC:1.3.3.6] synonym: "fatty acyl-CoA oxidase activity" EXACT [EC:1.3.3.6] synonym: "fatty acyl-coenzyme A oxidase activity" EXACT [EC:1.3.3.6] xref: EC:1.3.3.6 xref: GO:0003997 xref: MetaCyc:ACYL-COA-OXIDASE-RXN is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0000483 name: acylphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate." [EC:3.6.1.7] subset: gosubset_prok synonym: "1,3-diphosphoglycerate phosphatase activity" EXACT [EC:3.6.1.7] synonym: "acetic phosphatase activity" EXACT [EC:3.6.1.7] synonym: "acetylphosphatase activity" EXACT [EC:3.6.1.7] synonym: "acylphosphate phosphohydrolase activity" EXACT [EC:3.6.1.7] synonym: "GP 1-3" RELATED [EC:3.6.1.7] synonym: "Ho 1-3" RELATED [EC:3.6.1.7] xref: EC:3.6.1.7 xref: GO:0003998 xref: MetaCyc:ACYLPHOSPHATASE-RXN is_a: CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Term] id: CCO:F0000484 name: adenine phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.7] subset: gosubset_prok synonym: "adenine phosphoribosylpyrophosphate transferase activity" EXACT [EC:2.4.2.7] synonym: "adenosine phosphoribosyltransferase activity" EXACT [EC:2.4.2.7] synonym: "adenylate pyrophosphorylase activity" EXACT [EC:2.4.2.7] synonym: "adenylic pyrophosphorylase activity" EXACT [EC:2.4.2.7] synonym: "AMP diphosphorylase activity" EXACT [EC:2.4.2.7] synonym: "AMP pyrophosphorylase activity" EXACT [EC:2.4.2.7] synonym: "AMP-pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.7] synonym: "AMP:diphosphate phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.7] synonym: "APRT activity" EXACT [EC:2.4.2.7] synonym: "transphosphoribosidase activity" RELATED [EC:2.4.2.7] xref: EC:2.4.2.7 xref: GO:0003999 xref: MetaCyc:ADENPRIBOSYLTRAN-RXN xref: Reactome:12749 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000485 name: adenosine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine + H2O = inosine + NH3." [EC:3.5.4.4] subset: gosubset_prok synonym: "adenosine aminohydrolase activity" EXACT [EC:3.5.4.4] synonym: "adenosine deaminase reaction" EXACT [] xref: EC:3.5.4.4 xref: GO:0004000 xref: MetaCyc:ADENODEAMIN-RXN xref: Reactome:6985 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000486 name: adenosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + adenosine = ADP + AMP." [EC:2.7.1.20, PMID:11223943] subset: gosubset_prok synonym: "adenosine 5-phosphotransferase activity" EXACT [] synonym: "adenosine kinase (phosphorylating)" EXACT [EC:2.7.1.20] synonym: "ATP:adenosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.20] xref: EC:2.7.1.20 xref: GO:0004001 xref: MetaCyc:ADENOSINE-KINASE-RXN xref: Reactome:6989 is_a: CCO:F0004129 ! nucleoside kinase activity [Term] id: CCO:F0000487 name: ATP-dependent DNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of the DNA helix." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok xref: GO:0004003 is_a: CCO:F0000275 ! DNA helicase activity is_a: CCO:F0001682 ! ATP-dependent helicase activity is_a: CCO:F0001707 ! DNA-dependent ATPase activity [Term] id: CCO:F0000488 name: ATP-dependent RNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of an RNA helix." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok xref: GO:0004004 is_a: CCO:F0000309 ! RNA helicase activity is_a: CCO:F0001682 ! ATP-dependent helicase activity is_a: CCO:F0001767 ! RNA-dependent ATPase activity [Term] id: CCO:F0000489 name: copper-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) = ADP + phosphate + Cu2+(out)." [EC:3.6.3.4] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (Cu2+-exporting)" EXACT [EC:3.6.3.4] synonym: "copper exporting ATPase activity" EXACT [] synonym: "copper-translocating P-type ATPase activity" RELATED [EC:3.6.3.4] synonym: "Cu(2+)-exporting ATPase activity" EXACT [EC:3.6.3.4] synonym: "Cu2+-exporting ATPase activity" EXACT [EC:3.6.3.4] synonym: "cu2+-exporting ATPase activity" EXACT [EC:3.6.3.4] xref: EC:3.6.3.4 xref: GO:0004008 xref: MetaCyc:3.6.3.4-RXN is_a: CCO:F0005880 ! copper-transporting ATPase activity [Term] id: CCO:F0000490 name: phospholipid-translocating ATPase activity namespace: molecular_function def: "Catalysis of the movement of phospholipids from one membrane face to the other ('flippase' activity), driven by the hydrolysis of ATP." [EC:3.6.3.1, PMID:15919184, PMID:9099684] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "aminophospholipid-transporting ATPase" NARROW [] synonym: "ATP phosphohydrolase (phospholipid-flipping)" EXACT [EC:3.6.3.1] synonym: "flippase activity" BROAD [EC:3.6.3.1] synonym: "magnesium-ATPase activity" RELATED [EC:3.6.3.1] synonym: "Mg(2+)-ATPase activity" RELATED [EC:3.6.3.1] synonym: "Mg2+-ATPase activity" EXACT [EC:3.6.3.1] synonym: "phospholipid translocating ATPase activity" EXACT [] synonym: "phospholipid-transporting ATPase activity" EXACT [EC:3.6.3.1] xref: EC:3.6.3.1 xref: GO:0004012 xref: GO:0008557 xref: MetaCyc:3.6.3.1-RXN is_a: CCO:F0002715 ! aminophospholipid transporter activity is_a: CCO:F0005860 ! ATPase activity, coupled to movement of substances [Term] id: CCO:F0000491 name: adenosylhomocysteinase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine." [EC:3.3.1.1] subset: gosubset_prok synonym: "adenosylhomocysteine hydrolase activity" EXACT [EC:3.3.1.1] synonym: "AdoHcyase activity" EXACT [EC:3.3.1.1] synonym: "S-adenosyl-L-homocysteine hydrolase activity" EXACT [EC:3.3.1.1] synonym: "S-adenosylhomocysteinase activity" EXACT [EC:3.3.1.1] synonym: "S-adenosylhomocysteine hydrolase activity" BROAD [EC:3.3.1.1] synonym: "S-adenosylhomocysteine synthase activity" EXACT [EC:3.3.1.1] synonym: "SAHase activity" EXACT [EC:3.3.1.1] xref: EC:3.3.1.1 xref: GO:0004013 xref: MetaCyc:ADENOSYLHOMOCYSTEINASE-RXN xref: Reactome:7047 is_a: CCO:F0003372 ! trialkylsulfonium hydrolase activity [Term] id: CCO:F0000492 name: adenosylmethionine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine = (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt + CO2." [EC:4.1.1.50] subset: gosubset_prok synonym: "adenosyl methionine decarboxylase activity" EXACT [] synonym: "S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]" RELATED [EC:4.1.1.50] synonym: "S-adenosyl-L-methionine carboxy-lyase activity" EXACT [EC:4.1.1.50] synonym: "S-adenosyl-L-methionine decarboxylase activity" EXACT [EC:4.1.1.50] synonym: "S-adenosylmethionine decarboxylase activity" EXACT [EC:4.1.1.50] xref: EC:4.1.1.50 xref: GO:0004014 xref: MetaCyc:SAMDECARB-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000493 name: adenosylmethionine-8-amino-7-oxononanoate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate." [EC:2.6.1.62] subset: gosubset_prok synonym: "7,8-diamino-pelargonic acid aminotransferase activity" EXACT [EC:2.6.1.62] synonym: "7,8-diaminonanoate transaminase activity" EXACT [EC:2.6.1.62] synonym: "7,8-diaminononanoate aminotransferase activity" EXACT [EC:2.6.1.62] synonym: "7,8-diaminononanoate transaminase activity" EXACT [EC:2.6.1.62] synonym: "7,8-diaminopelargonic acid aminotransferase activity" EXACT [EC:2.6.1.62] synonym: "7-keto-8-aminopelargonic acid" RELATED [EC:2.6.1.62] synonym: "7-keto-8-aminopelargonic acid aminotransferase activity" EXACT [EC:2.6.1.62] synonym: "adenosyl methionine-8-amino-7-oxononanoate transaminase activity" EXACT [] synonym: "adenosylmethionine--8-amino-7-oxononanoate aminotransferase activity" EXACT [EC:2.6.1.62] synonym: "adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity" EXACT [] synonym: "DAPA aminotransferase activity" EXACT [EC:2.6.1.62] synonym: "DAPA transaminase activity" EXACT [EC:2.6.1.62] synonym: "diaminopelargonate synthase activity" EXACT [EC:2.6.1.62] synonym: "S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase activity" EXACT [EC:2.6.1.62] xref: EC:2.6.1.62 xref: GO:0004015 xref: MetaCyc:DAPASYN-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000494 name: adenylate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate." [EC:4.6.1.1] subset: gosubset_prok synonym: "3',5'-cyclic AMP synthetase activity" EXACT [EC:4.6.1.1] synonym: "adenyl cyclase activity" EXACT [EC:4.6.1.1] synonym: "adenylyl cyclase activity" EXACT [] synonym: "adenylylcyclase activity" EXACT [EC:4.6.1.1] synonym: "ATP diphosphate-lyase (cyclizing) activity" EXACT [EC:4.6.1.1] synonym: "ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity" EXACT [EC:4.6.1.1] synonym: "ATP pyrophosphate-lyase activity" EXACT [EC:4.6.1.1] synonym: "cAMP generating peptide activity" RELATED [] xref: EC:4.6.1.1 xref: GO:0004016 xref: MetaCyc:ADENYLATECYC-RXN xref: Reactome:7056 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0000495 name: adenylate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + AMP = 2 ADP." [EC:2.7.4.3] subset: gosubset_prok synonym: "5'-AMP-kinase activity" EXACT [EC:2.7.4.3] synonym: "adenylic kinase activity" EXACT [EC:2.7.4.3] synonym: "adenylokinase activity" EXACT [EC:2.7.4.3] synonym: "ATP:AMP phosphotransferase activity" EXACT [EC:2.7.4.3] synonym: "myokinase activity" NARROW [EC:2.7.4.3] xref: EC:2.7.4.3 xref: GO:0004017 xref: MetaCyc:ADENYL-KIN-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004124 ! nucleotide kinase activity [Term] id: CCO:F0000496 name: adenylosuccinate lyase activity namespace: molecular_function def: "Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP." [EC:4.3.2.2] subset: gosubset_prok synonym: "6-N-(1,2-dicarboxyethyl)AMP AMP-lyase activity" EXACT [EC:4.3.2.2] synonym: "adenylosuccinase activity" EXACT [EC:4.3.2.2] synonym: "N6-(1,2-dicarboxyethyl)AMP AMP-lyase activity" EXACT [EC:4.3.2.2] synonym: "succino AMP-lyase activity" EXACT [EC:4.3.2.2] xref: EC:4.3.2.2 xref: GO:0004018 xref: MetaCyc:AMPSYN-RXN xref: Reactome:7065 is_a: CCO:F0003407 ! amidine-lyase activity [Term] id: CCO:F0000497 name: adenylosuccinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + IMP + L-aspartate = GDP + phosphate + N6-(1,2-dicarboxyethyl)-AMP." [EC:6.3.4.4] subset: gosubset_prok synonym: "adenylosuccinate synthetase activity" EXACT [EC:6.3.4.4] synonym: "IMP--aspartate ligase activity" EXACT [EC:6.3.4.4] synonym: "IMP:L-aspartate ligase (GDP-forming)" EXACT [EC:6.3.4.4] synonym: "succino-AMP synthetase activity" EXACT [EC:6.3.4.4] synonym: "succinoadenylic kinosynthetase activity" EXACT [EC:6.3.4.4] xref: EC:6.3.4.4 xref: GO:0004019 xref: MetaCyc:ADENYLOSUCCINATE-SYNTHASE-RXN xref: Reactome:7069 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0000498 name: adenylylsulfate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate." [EC:2.7.1.25] subset: gosubset_prok synonym: "5'-phosphoadenosine sulfate kinase activity" EXACT [EC:2.7.1.25] synonym: "adenosine 5'-phosphosulfate kinase activity" EXACT [EC:2.7.1.25] synonym: "adenosine phosphosulfate kinase activity" EXACT [EC:2.7.1.25] synonym: "adenosine phosphosulfokinase activity" EXACT [EC:2.7.1.25] synonym: "adenosine-5'-phosphosulfate 3'-phosphotransferase activity" EXACT [] synonym: "adenosine-5'-phosphosulfate-3'-phosphokinase activity" EXACT [EC:2.7.1.25] synonym: "adenosine-5'-phosphosulphate 3'-phosphotransferase activity" EXACT [] synonym: "adenylyl-sulfate kinase activity" EXACT [] synonym: "adenylyl-sulphate kinase activity" EXACT [] synonym: "adenylylsulfate kinase (phosphorylating)" EXACT [EC:2.7.1.25] synonym: "APS kinase activity" EXACT [EC:2.7.1.25] synonym: "ATP:adenylyl-sulfate 3'-phosphotransferase activity" EXACT [EC:2.7.1.25] xref: EC:2.7.1.25 xref: GO:0004020 xref: MetaCyc:ADENYLYLSULFKIN-RXN xref: Reactome:7077 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000499 name: alanine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-alanine + 2-oxoglutarate = pyruvate + L-glutamate." [EC:2.6.1.2] subset: gosubset_prok synonym: "alanine aminotransferase activity" EXACT [] synonym: "alanine-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.2] synonym: "alanine-pyruvate aminotransferase activity" EXACT [EC:2.6.1.2] synonym: "ALT" RELATED [EC:2.6.1.2] synonym: "beta-alanine aminotransferase" BROAD [EC:2.6.1.2] synonym: "glutamic acid-pyruvic acid transaminase activity" EXACT [EC:2.6.1.2] synonym: "glutamic--alanine transaminase activity" EXACT [EC:2.6.1.2] synonym: "glutamic--pyruvic transaminase activity" EXACT [EC:2.6.1.2] synonym: "glutamic-pyruvic aminotransferase activity" EXACT [EC:2.6.1.2] synonym: "GPT" RELATED [EC:2.6.1.2] synonym: "L-alanine aminotransferase activity" EXACT [EC:2.6.1.2] synonym: "L-alanine transaminase activity" EXACT [EC:2.6.1.2] synonym: "L-alanine-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.2] synonym: "L-alanine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.2] synonym: "pyruvate transaminase activity" EXACT [EC:2.6.1.2] synonym: "pyruvate-alanine aminotransferase activity" EXACT [EC:2.6.1.2] synonym: "pyruvate-glutamate transaminase activity" EXACT [EC:2.6.1.2] xref: EC:2.6.1.2 xref: GO:0004021 xref: MetaCyc:ALANINE-AMINOTRANSFERASE-RXN xref: Reactome:7079 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000500 name: alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+." [EC:1.1.1.1] subset: gosubset_prok synonym: "ADH" RELATED [EC:1.1.1.1] synonym: "alcohol dehydrogenase (NAD) activity" NARROW [] synonym: "alcohol:NAD+ oxidoreductase" EXACT [EC:1.1.1.1] synonym: "aliphatic alcohol dehydrogenase" NARROW [EC:1.1.1.1] synonym: "ethanol dehydrogenase" NARROW [EC:1.1.1.1] synonym: "NAD-dependent alcohol dehydrogenase" EXACT [EC:1.1.1.1] synonym: "NAD-specific aromatic alcohol dehydrogenase" EXACT [EC:1.1.1.1] synonym: "NADH-alcohol dehydrogenase" EXACT [EC:1.1.1.1] synonym: "NADH-aldehyde dehydrogenase" EXACT [EC:1.1.1.1] synonym: "primary alcohol dehydrogenase" BROAD [EC:1.1.1.1] synonym: "yeast alcohol dehydrogenase" NARROW [EC:1.1.1.1] xref: EC:1.1.1.1 xref: GO:0004022 xref: MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN xref: UM-BBD_enzymeID:e0023 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000501 name: alcohol dehydrogenase activity, metal ion-independent namespace: molecular_function def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion." [EC:1.1.1.1, GOC:mah] xref: GO:0004023 is_a: CCO:F0000500 ! alcohol dehydrogenase activity [Term] id: CCO:F0000502 name: alcohol dehydrogenase activity, zinc-dependent namespace: molecular_function def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+ requiring the presence of zinc." [EC:1.1.1.1, GOC:mah] subset: gosubset_prok xref: GO:0004024 xref: Reactome:7085 is_a: CCO:F0000500 ! alcohol dehydrogenase activity [Term] id: CCO:F0000503 name: alcohol dehydrogenase activity, iron-dependent namespace: molecular_function def: "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron." [EC:1.1.1.1, GOC:mah] subset: gosubset_prok xref: GO:0004025 is_a: CCO:F0000500 ! alcohol dehydrogenase activity [Term] id: CCO:F0000504 name: alcohol O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester." [EC:2.3.1.84] synonym: "AATASE activity" EXACT [EC:2.3.1.84] synonym: "acetyl-CoA:alcohol O-acetyltransferase activity" EXACT [EC:2.3.1.84] synonym: "alcohol acetyltransferase activity" EXACT [EC:2.3.1.84] xref: EC:2.3.1.84 xref: GO:0004026 xref: MetaCyc:ALCOHOL-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity is_a: CCO:F0008349 ! alcohol O-acyltransferase activity [Term] id: CCO:F0000505 name: alcohol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate." [EC:2.8.2.2] subset: gosubset_prok synonym: "3'-phosphoadenylyl-sulfate:alcohol sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "3-hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "3beta-hydroxy steroid sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "3beta-hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "5alpha-androstenol sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "alcohol sulphotransferase activity" EXACT [] synonym: "alcohol/hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "dehydroepiandrosterone sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "delta5-3beta-hydroxysteroid sulfokinase activity" EXACT [EC:2.8.2.2] synonym: "estrogen sulfokinase activity" EXACT [EC:2.8.2.2] synonym: "estrogen sulfotransferase" BROAD [EC:2.8.2.2] synonym: "HST" RELATED [EC:2.8.2.2] synonym: "hydroxysteroid sulfotransferase activity" EXACT [EC:2.8.2.2] synonym: "steroid alcohol sulfotransferase" BROAD [EC:2.8.2.2] synonym: "steroid sulfokinase activity" EXACT [EC:2.8.2.2] synonym: "sterol sulfokinase activity" EXACT [EC:2.8.2.2] synonym: "sterol sulfotransferase activity" EXACT [EC:2.8.2.2] xref: EC:2.8.2.2 xref: GO:0004027 xref: MetaCyc:ALCOHOL-SULFOTRANSFERASE-RXN xref: Reactome:7092 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0000506 name: 3-chloroallyl aldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid." [UM-BBD_enzymeID:e0432] subset: gosubset_prok xref: EC:1.2.1.- xref: GO:0004028 xref: Reactome:7095 xref: UM-BBD_enzymeID:e0432 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000507 name: aldehyde dehydrogenase (NAD) activity namespace: molecular_function def: "Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+." [EC:1.2.1.3] subset: gosubset_prok synonym: "aldehyde dehydrogenase (NAD+)" EXACT [EC:1.2.1.3] synonym: "aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.3] synonym: "CoA-independent aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] synonym: "m-methylbenzaldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] synonym: "NAD-aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] synonym: "NAD-dependent 4-hydroxynonenal dehydrogenase activity" EXACT [EC:1.2.1.3] synonym: "NAD-dependent aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] synonym: "NAD-linked aldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] synonym: "propionaldehyde dehydrogenase activity" EXACT [EC:1.2.1.3] xref: EC:1.2.1.3 xref: GO:0004029 xref: MetaCyc:ALDHDEHYDROG-RXN xref: Reactome:7097 xref: UM-BBD_enzymeID:e0024 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000508 name: aldehyde dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+." [EC:1.2.1.5] subset: gosubset_prok synonym: "aldehyde:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.5] synonym: "ALDH" RELATED [EC:1.2.1.5] xref: EC:1.2.1.5 xref: GO:0004030 xref: MetaCyc:ALDEHYDE-DEHYDROGENASE-(NAD(P)+)-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000509 name: aldehyde oxidase activity namespace: molecular_function def: "Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + H2O2." [EC:1.2.3.1] subset: gosubset_prok synonym: "aldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.1] synonym: "quinoline oxidase activity" RELATED [EC:1.2.3.1] xref: EC:1.2.3.1 xref: GO:0004031 xref: MetaCyc:ALDEHYDE-OXIDASE-RXN is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0000510 name: aldehyde reductase activity namespace: molecular_function def: "Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+." [EC:1.1.1.21] subset: gosubset_prok synonym: "aldose reductase activity" EXACT [EC:1.1.1.21] synonym: "polyol dehydrogenase (NADP(+)) activity" RELATED [EC:1.1.1.21] xref: EC:1.1.1.21 xref: GO:0004032 xref: MetaCyc:ALDEHYDE-REDUCTASE-RXN is_a: CCO:F0000511 ! aldo-keto reductase activity [Term] id: CCO:F0000511 name: aldo-keto reductase activity namespace: molecular_function def: "Catalysis of the NADPH-dependent reduction of carbonyl compounds." [GOC:jl, PMID:2498333] subset: gosubset_prok xref: EC:1.1.1.- xref: GO:0004033 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000512 name: aldose 1-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose." [EC:5.1.3.3] subset: gosubset_prok synonym: "aldose mutarotase activity" RELATED [EC:5.1.3.3] synonym: "mutarotase activity" RELATED [EC:5.1.3.3] xref: EC:5.1.3.3 xref: GO:0004034 xref: MetaCyc:ALDOSE-1-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0000513 name: alkaline phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [EC:3.1.3.1] subset: gosubset_prok synonym: "alkaline phenyl phosphatase activity" EXACT [EC:3.1.3.1] synonym: "alkaline phosphohydrolase activity" EXACT [EC:3.1.3.1] synonym: "alkaline phosphomonoesterase activity" EXACT [EC:3.1.3.1] synonym: "glycerophosphatase activity" BROAD [EC:3.1.3.1] synonym: "orthophosphoric-monoester phosphohydrolase (alkaline optimum)" EXACT [EC:3.1.3.1] synonym: "phosphate-monoester phosphohydrolase (alkaline optimum)" EXACT [EC:3.1.3.1] synonym: "phosphomonoesterase activity" BROAD [EC:3.1.3.1] xref: EC:3.1.3.1 xref: GO:0004035 xref: MetaCyc:ALKAPHOSPHA-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000514 name: allantoicase activity namespace: molecular_function def: "Catalysis of the reaction: allantoate + H2O = (-)-ureidoglycolate + urea." [EC:3.5.3.4] subset: gosubset_prok synonym: "allantoate amidinohydrolase activity" EXACT [EC:3.5.3.4] synonym: "allantoine amidinohydrolase activity" EXACT [] xref: EC:3.5.3.4 xref: GO:0004037 xref: MetaCyc:ALLANTOICASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0000515 name: allantoinase activity namespace: molecular_function def: "Catalysis of the reaction: allantoin + H2O = allantoate." [EC:3.5.2.5] subset: gosubset_prok synonym: "(S)-allantoin amidohydrolase activity" EXACT [EC:3.5.2.5] xref: EC:3.5.2.5 xref: GO:0004038 xref: MetaCyc:ALLANTOINASE-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0000516 name: allophanate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: urea-1-carboxylate + H2O = 2 CO2 + 2 NH3." [EC:3.5.1.54] subset: gosubset_prok synonym: "allophanate lyase activity" EXACT [EC:3.5.1.54] synonym: "urea-1-carboxylate amidohydrolase activity" EXACT [EC:3.5.1.54] xref: EC:3.5.1.54 xref: GO:0004039 xref: MetaCyc:ALLOPHANATE-HYDROLASE-RXN xref: UM-BBD_enzymeID:e0534 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000517 name: amidase activity namespace: molecular_function def: "Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3." [EC:3.5.1.4] subset: gosubset_prok synonym: "acetamidase activity" EXACT [] synonym: "acylamidase activity" EXACT [EC:3.5.1.4] synonym: "acylamide amidohydrolase activity" EXACT [EC:3.5.1.4] synonym: "acylase activity" EXACT [EC:3.5.1.4] synonym: "amidohydrolase activity" EXACT [EC:3.5.1.4] synonym: "fatty acylamidase activity" EXACT [EC:3.5.1.4] synonym: "N-acetylaminohydrolase activity" EXACT [EC:3.5.1.4] xref: EC:3.5.1.4 xref: GO:0004040 xref: MetaCyc:AMIDASE-RXN xref: UM-BBD_enzymeID:e0068 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000518 name: amino-acid N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate." [EC:2.3.1.1] subset: gosubset_prok synonym: "acetyl-CoA:L-glutamate N-acetyltransferase activity" EXACT [EC:2.3.1.1] synonym: "acetylglutamate acetylglutamate synthetase activity" EXACT [EC:2.3.1.1] synonym: "AGAS" RELATED [EC:2.3.1.1] synonym: "amino acid acetyltransferase activity" EXACT [EC:2.3.1.1] synonym: "N-acetylglutamate synthase activity" BROAD [EC:2.3.1.1] xref: EC:2.3.1.1 xref: GO:0004042 xref: MetaCyc:N-ACETYLTRANSFER-RXN xref: Reactome:7143 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0000519 name: L-aminoadipate-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+." [EC:1.2.1.31] subset: gosubset_prok synonym: "2-aminoadipate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] synonym: "2-aminoadipic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] synonym: "AAR" EXACT [EC:1.2.1.31] synonym: "alpha-aminoadipate reductase activity" EXACT [EC:1.2.1.31] synonym: "alpha-aminoadipate-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] synonym: "aminoadipate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] synonym: "aminoadipate-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.31] synonym: "L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase" EXACT [EC:1.2.1.31] synonym: "L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity" EXACT [EC:1.2.1.31] synonym: "L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity" EXACT [EC:1.2.1.31] synonym: "L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity" EXACT [EC:1.2.1.31] xref: EC:1.2.1.31 xref: GO:0004043 xref: MetaCyc:1.2.1.31-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000520 name: amidophosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O." [EC:2.4.2.14] subset: gosubset_prok synonym: "5'-phosphoribosylpyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "5-phosphoribosyl-1-pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)" EXACT [EC:2.4.2.14] synonym: "5-phosphororibosyl-1-pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "glutamine 5-phosphoribosylpyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "glutamine phosphoribosyldiphosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "glutamine phosphoribosylpyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "phosphoribose pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "phosphoribosyl pyrophosphate amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "phosphoribosyldiphosphate 5-amidotransferase activity" EXACT [EC:2.4.2.14] synonym: "phosphoribosylpyrophosphate glutamyl amidotransferase activity" EXACT [EC:2.4.2.14] xref: EC:2.4.2.14 xref: GO:0004044 xref: MetaCyc:PRPPAMIDOTRANS-RXN xref: Reactome:7147 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000521 name: aminoacyl-tRNA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA." [EC:3.1.1.29] subset: gosubset_prok synonym: "aminoacyl-transfer ribonucleate hydrolase activity" EXACT [EC:3.1.1.29] synonym: "aminoacyl-tRNA aminoacylhydrolase activity" EXACT [EC:3.1.1.29] synonym: "aminoacyl-tRNA hydrolase reaction" EXACT [] synonym: "N-substituted aminoacyl transfer RNA hydrolase activity" EXACT [EC:3.1.1.29] synonym: "peptidyl-tRNA hydrolase activity" EXACT [EC:3.1.1.29] xref: EC:3.1.1.29 xref: GO:0004045 xref: GO:0019850 xref: MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0000522 name: aminoacylase activity namespace: molecular_function def: "Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid." [EC:3.5.1.14] subset: gosubset_prok synonym: "acylase I activity" NARROW [EC:3.5.1.14] synonym: "alpha-N-acylaminoacid hydrolase activity" EXACT [EC:3.5.1.14] synonym: "amido acid deacylase activity" EXACT [EC:3.5.1.14] synonym: "aminoacylase I activity" NARROW [EC:3.5.1.14] synonym: "benzamidase activity" RELATED [EC:3.5.1.14] synonym: "dehydropeptidase II activity" NARROW [EC:3.5.1.14] synonym: "hippurase activity" EXACT [EC:3.5.1.14] synonym: "histozyme activity" RELATED [EC:3.5.1.14] synonym: "L-amino-acid acylase activity" EXACT [EC:3.5.1.14] synonym: "L-aminoacylase activity" EXACT [EC:3.5.1.14] synonym: "long acyl amidoacylase activity" EXACT [EC:3.5.1.14] synonym: "N-acyl-L-amino-acid amidohydrolase activity" EXACT [EC:3.5.1.14] synonym: "short acyl amidoacylase activity" EXACT [EC:3.5.1.14] xref: EC:3.5.1.14 xref: GO:0004046 xref: MetaCyc:AMINOACYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000523 name: aminomethyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein." [EC:2.1.2.10] subset: gosubset_prok synonym: "glycine synthase activity" RELATED [EC:2.1.2.10] synonym: "glycine-cleavage system T-protein activity" RELATED [EC:2.1.2.10] synonym: "protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity" EXACT [EC:2.1.2.10] synonym: "protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity" EXACT [EC:2.1.2.10] synonym: "S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity" EXACT [EC:2.1.2.10] synonym: "T-protein" RELATED [EC:2.1.2.10] synonym: "tetrahydrofolate aminomethyltransferase activity" EXACT [EC:2.1.2.10] xref: EC:2.1.2.10 xref: GO:0004047 xref: MetaCyc:GCVT-RXN is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0000524 name: anthranilate phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-a-D-ribose 1-diphosphate." [EC:2.4.2.18] subset: gosubset_prok synonym: "anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.18] synonym: "anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.18] synonym: "anthranilate-PP-ribose-P phosphoribosyltransferase activity" EXACT [EC:2.4.2.18] synonym: "N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.18] synonym: "phosphoribosyl-anthranilate diphosphorylase activity" EXACT [EC:2.4.2.18] synonym: "phosphoribosyl-anthranilate pyrophosphorylase activity" EXACT [EC:2.4.2.18] synonym: "phosphoribosylanthranilate pyrophosphorylase activity" EXACT [EC:2.4.2.18] synonym: "phosphoribosylanthranilate transferase activity" EXACT [EC:2.4.2.18] synonym: "PRT" RELATED [EC:2.4.2.18] xref: EC:2.4.2.18 xref: GO:0004048 xref: MetaCyc:PRTRANS-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000525 name: anthranilate synthase activity namespace: molecular_function def: "Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate." [EC:4.1.3.27] subset: gosubset_prok synonym: "anthranilate synthetase activity" EXACT [EC:4.1.3.27] synonym: "chorismate pyruvate-lyase (amino-accepting) activity" EXACT [EC:4.1.3.27] xref: EC:4.1.3.27 xref: GO:0004049 xref: MetaCyc:ANTHRANSYN-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0000526 name: arachidonate 5-lipoxygenase activity namespace: molecular_function def: "Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate." [EC:1.13.11.34] subset: gosubset_prok synonym: "5-delta-lipoxygenase activity" EXACT [EC:1.13.11.34] synonym: "5-lipoxygenase activity" EXACT [EC:1.13.11.34] synonym: "5Delta-lipoxygenase activity" EXACT [EC:1.13.11.34] synonym: "arachidonate:oxygen 5-oxidoreductase activity" EXACT [EC:1.13.11.34] synonym: "arachidonic 5-lipoxygenase activity" EXACT [EC:1.13.11.34] synonym: "arachidonic acid 5-lipoxygenase activity" EXACT [EC:1.13.11.34] synonym: "C-5-lipoxygenase activity" RELATED [EC:1.13.11.34] synonym: "delta(5)-lipoxygenase activity" RELATED [EC:1.13.11.34] synonym: "delta5-lipoxygenase activity" EXACT [EC:1.13.11.34] synonym: "leukotriene A4 synthase" BROAD [EC:1.13.11.34] synonym: "leukotriene-A(4) synthase activity" NARROW [EC:1.13.11.34] synonym: "leukotriene-A4 synthase activity" EXACT [EC:1.13.11.34] synonym: "LTA synthase activity" NARROW [EC:1.13.11.34] xref: EC:1.13.11.34 xref: GO:0004051 xref: MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0000527 name: arachidonate 12-lipoxygenase activity namespace: molecular_function def: "Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate." [EC:1.13.11.31] synonym: "12-lipoxygenase activity" RELATED [EC:1.13.11.31] synonym: "12Delta-lipoxygenase activity" EXACT [EC:1.13.11.31] synonym: "12S-lipoxygenase activity" EXACT [EC:1.13.11.31] synonym: "arachidonate:oxygen 12-oxidoreductase activity" EXACT [EC:1.13.11.31] synonym: "C-12 lipoxygenase activity" EXACT [EC:1.13.11.31] synonym: "delta12-lipoxygenase activity" EXACT [EC:1.13.11.31] synonym: "leukotriene A4 synthase" BROAD [EC:1.13.11.31] synonym: "LTA4 synthase activity" EXACT [EC:1.13.11.31] xref: EC:1.13.11.31 xref: GO:0004052 xref: MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0000528 name: arginase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea." [EC:3.5.3.1] subset: gosubset_prok synonym: "arginine amidinase activity" EXACT [EC:3.5.3.1] synonym: "arginine transamidinase activity" EXACT [EC:3.5.3.1] synonym: "canavanase activity" EXACT [EC:3.5.3.1] synonym: "L-arginase activity" EXACT [EC:3.5.3.1] synonym: "L-arginine amidinohydrolase activity" EXACT [EC:3.5.3.1] xref: EC:3.5.3.1 xref: GO:0004053 xref: MetaCyc:ARGINASE-RXN xref: Reactome:7167 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0000529 name: arginine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-arginine = ADP + N-phospho-L-arginine." [EC:2.7.3.3] synonym: "adenosine 5'-triphosphate-arginine phosphotransferase activity" EXACT [EC:2.7.3.3] synonym: "adenosine 5'-triphosphate:L-arginine" RELATED [EC:2.7.3.3] synonym: "arginine phosphokinase activity" EXACT [EC:2.7.3.3] synonym: "ATP:L-arginine N-phosphotransferase activity" EXACT [EC:2.7.3.3] xref: EC:2.7.3.3 xref: GO:0004054 xref: MetaCyc:ARGININE-KINASE-RXN is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor is_a: CCO:F0004125 ! amino acid kinase activity [Term] id: CCO:F0000530 name: argininosuccinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate." [EC:6.3.4.5] subset: gosubset_prok synonym: "arginine succinate synthetase activity" EXACT [EC:6.3.4.5] synonym: "argininosuccinate synthetase activity" EXACT [EC:6.3.4.5] synonym: "argininosuccinic acid synthetase activity" EXACT [EC:6.3.4.5] synonym: "arginosuccinate synthetase activity" EXACT [EC:6.3.4.5] synonym: "citrulline--aspartate ligase activity" EXACT [EC:6.3.4.5] synonym: "L-citrulline:L-aspartate ligase (AMP-forming)" EXACT [EC:6.3.4.5] xref: EC:6.3.4.5 xref: GO:0004055 xref: MetaCyc:ARGSUCCINSYN-RXN xref: Reactome:7171 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0000531 name: argininosuccinate lyase activity namespace: molecular_function def: "Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine." [EC:4.3.2.1] subset: gosubset_prok synonym: "2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)" EXACT [EC:4.3.2.1] synonym: "2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)" EXACT [EC:4.3.2.1] synonym: "arginine-succinate lyase activity" EXACT [EC:4.3.2.1] synonym: "argininosuccinic acid lyase activity" EXACT [EC:4.3.2.1] synonym: "arginosuccinase activity" EXACT [EC:4.3.2.1] synonym: "N-(L-argininosuccinate) arginine-lyase activity" EXACT [EC:4.3.2.1] synonym: "omega-N-(L-arginino)succinate arginine-lyase activity" EXACT [EC:4.3.2.1] xref: EC:4.3.2.1 xref: GO:0004056 xref: MetaCyc:ARGSUCCINLYA-RXN xref: Reactome:7173 is_a: CCO:F0003407 ! amidine-lyase activity [Term] id: CCO:F0000532 name: arginyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein." [EC:2.3.2.8] subset: gosubset_prok synonym: "arginine transferase activity" EXACT [EC:2.3.2.8] synonym: "arginyl-transfer ribonucleate-protein aminoacyltransferase activity" EXACT [EC:2.3.2.8] synonym: "arginyl-transfer ribonucleate-protein transferase activity" EXACT [EC:2.3.2.8] synonym: "arginyl-tRNA protein transferase activity" EXACT [EC:2.3.2.8] synonym: "arginyl-tRNA--protein transferase activity" EXACT [EC:2.3.2.8] synonym: "arginyl-tRNA-protein transferase activity" EXACT [] synonym: "L-arginyl-tRNA:protein arginyltransferase activity" EXACT [EC:2.3.2.8] xref: EC:2.3.2.8 xref: GO:0004057 xref: GO:0042172 xref: MetaCyc:ARGINYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0000533 name: aromatic-L-amino-acid decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan = tryptamine + CO2." [EC:4.1.1.28] synonym: "5-hydroxytryptophan decarboxylase activity" EXACT [EC:4.1.1.28] synonym: "aromatic amino acid decarboxylase activity" EXACT [EC:4.1.1.28] synonym: "aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)" EXACT [EC:4.1.1.28] synonym: "aromatic-L-amino-acid carboxy-lyase activity" EXACT [EC:4.1.1.28] synonym: "DOPA decarboxylase activity" EXACT [EC:4.1.1.28] synonym: "hydroxytryptophan decarboxylase activity" EXACT [EC:4.1.1.28] synonym: "L-DOPA decarboxylase activity" EXACT [EC:4.1.1.28] synonym: "tryptophan decarboxylase activity" EXACT [EC:4.1.1.28] xref: EC:4.1.1.28 xref: GO:0004058 xref: GO:0016400 xref: MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000534 name: aralkylamine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine." [EC:2.3.1.87] synonym: "AANAT activity" EXACT [EC:2.3.1.87] synonym: "acetyl-CoA:2-arylethylamine N-acetyltransferase activity" EXACT [EC:2.3.1.87] synonym: "arylalkylamine N-acetyltransferase activity" EXACT [EC:2.3.1.87] synonym: "melatonin rhythm enzyme activity" RELATED [EC:2.3.1.87] synonym: "serotonin acetylase activity" NARROW [EC:2.3.1.87] synonym: "serotonin acetyltransferase activity" NARROW [EC:2.3.1.87] synonym: "serotonin N-acetyltransferase activity" NARROW [EC:2.3.1.87] xref: EC:2.3.1.87 xref: GO:0004059 xref: MetaCyc:ARALKYLAMINE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0000535 name: arylamine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine." [EC:2.3.1.5] subset: gosubset_prok synonym: "2-naphthylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] synonym: "4-aminobiphenyl N-acetyltransferase activity" EXACT [EC:2.3.1.5] synonym: "acetyl CoA-arylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] synonym: "acetyl-CoA:arylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] synonym: "arylamine acetylase activity" EXACT [EC:2.3.1.5] synonym: "arylamine acetyltransferase activity" EXACT [EC:2.3.1.5] synonym: "beta-naphthylamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] synonym: "indoleamine N-acetyltransferase activity" EXACT [EC:2.3.1.5] synonym: "p-aminosalicylate N-acetyltransferase activity" EXACT [EC:2.3.1.5] xref: EC:2.3.1.5 xref: GO:0004060 xref: MetaCyc:ARYLAMINE-N-ACETYLTRANSFERASE-RXN xref: Reactome:7187 xref: UM-BBD_enzymeID:e0341 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0000536 name: arylformamidase activity namespace: molecular_function def: "Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine." [EC:3.5.1.9] subset: gosubset_prok synonym: "aryl-formylamine amidohydrolase activity" EXACT [EC:3.5.1.9] synonym: "formamidase I" RELATED [EC:3.5.1.9] synonym: "formamidase II" RELATED [EC:3.5.1.9] synonym: "formylase activity" EXACT [EC:3.5.1.9] synonym: "formylkynureninase activity" EXACT [EC:3.5.1.9] synonym: "formylkynurenine formamidase activity" EXACT [EC:3.5.1.9] synonym: "kynurenine formamidase activity" EXACT [EC:3.5.1.9] xref: EC:3.5.1.9 xref: GO:0004061 xref: MetaCyc:ARYLFORMAMIDASE-RXN xref: Reactome:7190 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000537 name: aryl sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate." [EC:2.8.2.1] subset: gosubset_prok synonym: "1-naphthol phenol sulfotransferase activity" EXACT [EC:2.8.2.1] synonym: "2-naphtholsulfotransferase activity" EXACT [EC:2.8.2.1] synonym: "3'-phosphoadenylyl-sulfate:phenol sulfotransferase activity" EXACT [EC:2.8.2.1] synonym: "4-nitrocatechol sulfokinase activity" EXACT [EC:2.8.2.1] synonym: "aryl sulphotransferase activity" EXACT [] synonym: "arylsulfotransferase" BROAD [EC:2.8.2.1] synonym: "dopamine sulfotransferase activity" EXACT [EC:2.8.2.1] synonym: "p-nitrophenol sulfotransferase activity" EXACT [EC:2.8.2.1] synonym: "phenol sulfokinase activity" EXACT [EC:2.8.2.1] synonym: "phenol sulfotransferase activity" EXACT [EC:2.8.2.1] synonym: "PST" RELATED [EC:2.8.2.1] synonym: "ritodrine sulfotransferase activity" EXACT [EC:2.8.2.1] synonym: "sulfokinase activity" RELATED [EC:2.8.2.1] xref: EC:2.8.2.1 xref: GO:0004062 xref: MetaCyc:ARYL-SULFOTRANSFERASE-RXN xref: Reactome:7193 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0000538 name: aryldialkylphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol." [EC:3.1.8.1] subset: gosubset_prok synonym: "A-esterase activity" BROAD [EC:3.1.8.1] synonym: "aryltriphosphatase activity" EXACT [EC:3.1.8.1] synonym: "aryltriphosphate dialkylphosphohydrolase activity" EXACT [EC:3.1.8.1] synonym: "esterase B1" RELATED [EC:3.1.8.1] synonym: "esterase E4" RELATED [EC:3.1.8.1] synonym: "OPH" RELATED [EC:3.1.8.1] synonym: "organophosphate esterase activity" EXACT [EC:3.1.8.1] synonym: "organophosphate hydrolase activity" EXACT [EC:3.1.8.1] synonym: "organophosphorus acid anhydrase activity" EXACT [EC:3.1.8.1] synonym: "organophosphorus hydrolase activity" EXACT [EC:3.1.8.1] synonym: "paraoxon esterase activity" EXACT [EC:3.1.8.1] synonym: "paraoxon hydrolase activity" BROAD [EC:3.1.8.1] synonym: "paraoxonase activity" BROAD [EC:3.1.8.1] synonym: "phosphotriesterase activity" EXACT [EC:3.1.8.1] synonym: "pirimiphos-methyloxon esterase activity" EXACT [EC:3.1.8.1] xref: EC:3.1.8.1 xref: GO:0004063 xref: MetaCyc:ARYLDIALKYLPHOSPHATASE-RXN xref: UM-BBD_enzymeID:e0054 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000539 name: arylesterase activity namespace: molecular_function def: "Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate." [EC:3.1.1.2] subset: gosubset_prok synonym: "A-esterase activity" BROAD [EC:3.1.1.2] synonym: "aromatic esterase" NARROW [EC:3.1.1.2] synonym: "aryl-ester hydrolase" NARROW [EC:3.1.1.2] synonym: "paraoxonase activity" BROAD [EC:3.1.1.2] xref: EC:3.1.1.2 xref: GO:0004064 xref: MetaCyc:ARYLESTERASE-RXN xref: UM-BBD_enzymeID:e0535 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0000540 name: arylsulfatase activity namespace: molecular_function def: "Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate)." [EC:3.1.6.1] subset: gosubset_prok synonym: "4-methylumbelliferyl sulfatase activity" EXACT [EC:3.1.6.1] synonym: "aryl-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.1] synonym: "aryl-sulfate sulphohydrolase activity" EXACT [EC:3.1.6.1] synonym: "aryl-sulphate sulphohydrolase activity" EXACT [EC:3.1.6.1] synonym: "arylsulfohydrolase activity" EXACT [EC:3.1.6.1] synonym: "arylsulphatase activity" EXACT [] synonym: "estrogen sulfatase activity" EXACT [EC:3.1.6.1] synonym: "nitrocatechol sulfatase activity" EXACT [EC:3.1.6.1] synonym: "p-nitrophenyl sulfatase activity" EXACT [EC:3.1.6.1] synonym: "phenolsulfatase activity" EXACT [EC:3.1.6.1] synonym: "phenylsulfatase activity" EXACT [EC:3.1.6.1] synonym: "sulfatase activity" RELATED [EC:3.1.6.1] xref: EC:3.1.6.1 xref: GO:0004065 xref: MetaCyc:ARYLSULFAT-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0000541 name: asparagine synthase (glutamine-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate." [EC:6.3.5.4] subset: gosubset_prok synonym: "AS" RELATED [EC:6.3.5.4] synonym: "AS-B activity" EXACT [EC:6.3.5.4] synonym: "asparagine synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.4] synonym: "asparagine synthetase (glutamine-hydrolysing)" EXACT [EC:6.3.5.4] synonym: "asparagine synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.4] synonym: "asparagine synthetase B activity" EXACT [EC:6.3.5.4] synonym: "glutamine-dependent asparagine synthetase activity" EXACT [EC:6.3.5.4] synonym: "L-aspartate:L-glutamine amido-ligase (AMP-forming)" EXACT [EC:6.3.5.4] xref: EC:6.3.5.4 xref: GO:0004066 xref: MetaCyc:ASNSYNB-RXN xref: Reactome:7213 is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0000542 name: asparaginase activity namespace: molecular_function def: "Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3." [EC:3.5.1.1] subset: gosubset_prok synonym: "alpha-asparaginase activity" EXACT [EC:3.5.1.1] synonym: "asparaginase II" RELATED [EC:3.5.1.1] synonym: "colaspase activity" EXACT [EC:3.5.1.1] synonym: "crasnitin" RELATED [EC:3.5.1.1] synonym: "elspar" RELATED [EC:3.5.1.1] synonym: "L-asparaginase activity" EXACT [EC:3.5.1.1] synonym: "L-asparagine amidohydrolase activity" EXACT [EC:3.5.1.1] synonym: "leunase activity" EXACT [EC:3.5.1.1] xref: EC:3.5.1.1 xref: GO:0004067 xref: MetaCyc:ASPARAGHYD-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000543 name: aspartate 1-decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate = beta-alanine + CO2." [EC:4.1.1.11] subset: gosubset_prok synonym: "aspartate alpha-decarboxylase activity" EXACT [EC:4.1.1.11] synonym: "aspartic alpha-decarboxylase" BROAD [EC:4.1.1.11] synonym: "L-aspartate 1-carboxy-lyase (beta-alanine-forming)" EXACT [EC:4.1.1.11] synonym: "L-aspartate 1-carboxy-lyase activity" EXACT [EC:4.1.1.11] synonym: "L-aspartate alpha-decarboxylase activity" EXACT [EC:4.1.1.11] xref: EC:4.1.1.11 xref: GO:0004068 xref: MetaCyc:ASPDECARBOX-RXN xref: MetaCyc:PWY-5155 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000544 name: aspartate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate." [EC:2.6.1.1] subset: gosubset_prok synonym: "2-oxoglutarate-glutamate aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "AAT" RELATED [EC:2.6.1.1] synonym: "aspartate alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.1] synonym: "aspartate aminotransferase activity" EXACT [] synonym: "aspartate-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.1] synonym: "aspartate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "aspartic acid aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "aspartic aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "aspartyl aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "AspT" RELATED [EC:2.6.1.1] synonym: "glutamate oxaloacetate transaminase activity" EXACT [EC:2.6.1.1] synonym: "glutamate-oxalacetate aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "glutamate-oxalate transaminase activity" EXACT [EC:2.6.1.1] synonym: "glutamic oxalic transaminase activity" EXACT [EC:2.6.1.1] synonym: "glutamic--aspartic transaminase activity" EXACT [EC:2.6.1.1] synonym: "glutamic--oxaloacetic transaminase activity" EXACT [EC:2.6.1.1] synonym: "glutamic-aspartic aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "glutamic-oxalacetic transaminase activity" EXACT [EC:2.6.1.1] synonym: "GOT (enzyme)" RELATED [EC:2.6.1.1] synonym: "L-aspartate transaminase activity" EXACT [EC:2.6.1.1] synonym: "L-aspartate-2-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "L-aspartate-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "L-aspartate-2-oxoglutarate-transaminase activity" EXACT [EC:2.6.1.1] synonym: "L-aspartate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.1] synonym: "L-aspartate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "L-aspartic aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "oxaloacetate transferase activity" EXACT [EC:2.6.1.1] synonym: "oxaloacetate-aspartate aminotransferase activity" EXACT [EC:2.6.1.1] synonym: "transaminase A activity" EXACT [EC:2.6.1.1] xref: EC:2.6.1.1 xref: GO:0004069 xref: MetaCyc:ASPAMINOTRANS-RXN xref: Reactome:7220 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000545 name: aspartate carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate." [EC:2.1.3.2] subset: gosubset_prok synonym: "aspartate carbamyltransferase activity" EXACT [EC:2.1.3.2] synonym: "aspartate transcarbamoylase activity" EXACT [EC:2.1.3.2] synonym: "aspartate transcarbamylase activity" EXACT [EC:2.1.3.2] synonym: "aspartic acid transcarbamoylase activity" EXACT [EC:2.1.3.2] synonym: "aspartic carbamyltransferase activity" EXACT [EC:2.1.3.2] synonym: "aspartic transcarbamylase activity" EXACT [EC:2.1.3.2] synonym: "ATCase activity" EXACT [EC:2.1.3.2] synonym: "carbamoyl-phosphate:L-aspartate carbamoyltransferase activity" EXACT [EC:2.1.3.2] synonym: "carbamoylaspartotranskinase activity" EXACT [EC:2.1.3.2] synonym: "carbamylaspartotranskinase activity" EXACT [EC:2.1.3.2] synonym: "L-aspartate transcarbamoylase activity" EXACT [EC:2.1.3.2] synonym: "L-aspartate transcarbamylase activity" EXACT [EC:2.1.3.2] xref: EC:2.1.3.2 xref: GO:0004070 xref: MetaCyc:ASPCARBTRANS-RXN xref: Reactome:7225 is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0000546 name: aspartate-ammonia ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine." [EC:6.3.1.1] subset: gosubset_prok synonym: "asparagine synthetase activity" EXACT [EC:6.3.1.1] synonym: "L-asparagine synthetase activity" EXACT [EC:6.3.1.1] synonym: "L-aspartate:ammonia ligase (AMP-forming)" EXACT [EC:6.3.1.1] xref: EC:6.3.1.1 xref: GO:0004071 xref: MetaCyc:ASNSYNA-RXN is_a: CCO:F0003071 ! ammonia ligase activity [Term] id: CCO:F0000547 name: aspartate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-aspartate = ADP + 4-phospho-L-aspartate." [EC:2.7.2.4] subset: gosubset_prok synonym: "aspartic kinase activity" EXACT [EC:2.7.2.4] synonym: "aspartokinase activity" EXACT [EC:2.7.2.4] synonym: "ATP:L-aspartate 4-phosphotransferase activity" EXACT [EC:2.7.2.4] synonym: "beta-aspartokinase activity" EXACT [EC:2.7.2.4] xref: EC:2.7.2.4 xref: GO:0004072 xref: MetaCyc:ASPARTATEKIN-RXN is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor is_a: CCO:F0004125 ! amino acid kinase activity [Term] id: CCO:F0000548 name: aspartate-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate-4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH + H+." [EC:1.2.1.11] subset: gosubset_prok synonym: "ASA dehydrogenase activity" EXACT [EC:1.2.1.11] synonym: "aspartate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] synonym: "aspartic beta-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] synonym: "aspartic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] synonym: "L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.11] synonym: "L-aspartate-beta-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.11] synonym: "L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating)" EXACT [EC:1.2.1.11] xref: EC:1.2.1.11 xref: GO:0004073 xref: MetaCyc:ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000549 name: biliverdin reductase activity namespace: molecular_function def: "Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+." [EC:1.3.1.24] synonym: "bilirubin:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.24] xref: EC:1.3.1.24 xref: GO:0004074 xref: MetaCyc:BILIVERDIN-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000550 name: biotin carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein." [EC:6.3.4.14] subset: gosubset_prok synonym: "biotin carboxylase (component of acetyl CoA carboxylase) activity" EXACT [EC:6.3.4.14] synonym: "biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming) activity" EXACT [EC:6.3.4.14] xref: EC:6.3.4.14 xref: GO:0004075 xref: MetaCyc:BIOTIN-CARBOXYL-RXN is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0000551 name: biotin synthase activity namespace: molecular_function def: "Catalysis of the reaction: dethiobiotin + sulfur = biotin." [EC:2.8.1.6] subset: gosubset_prok synonym: "biotin synthetase activity" EXACT [EC:2.8.1.6] synonym: "dethiobiotin:sulfur sulfurtransferase activity" EXACT [EC:2.8.1.6] xref: EC:2.8.1.6 xref: GO:0004076 xref: MetaCyc:2.8.1.6-RXN is_a: CCO:F0003355 ! sulfurtransferase activity [Term] id: CCO:F0000552 name: biotin-[acetyl-CoA-carboxylase] ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming))." [EC:6.3.4.15] subset: gosubset_prok synonym: "acetyl CoA holocarboxylase synthetase activity" EXACT [EC:6.3.4.15] synonym: "acetyl coenzyme A holocarboxylase synthetase activity" EXACT [EC:6.3.4.15] synonym: "acetyl-CoA carboxylase biotin holoenzyme synthetase activity" EXACT [EC:6.3.4.15] synonym: "biotin holoenzyme synthetase activity" EXACT [EC:6.3.4.15] synonym: "biotin--[acetyl-CoA carboxylase] synthetase activity" EXACT [EC:6.3.4.15] synonym: "biotin--protein ligase activity" RELATED [EC:6.3.4.15] synonym: "biotin-acetyl coenzyme A carboxylase synthetase activity" EXACT [EC:6.3.4.15] synonym: "biotin-acetyl-CoA carboxylase synthetase" BROAD [EC:6.3.4.15] synonym: "biotin-acetyl-CoA-carboxylase ligase activity" EXACT [EC:6.3.4.15] synonym: "biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)" EXACT [EC:6.3.4.15] synonym: "biotin:apocarboxylase ligase activity" EXACT [EC:6.3.4.15] synonym: "HCS" RELATED [EC:6.3.4.15] xref: EC:6.3.4.15 xref: GO:0004077 xref: MetaCyc:BIOTINLIG-RXN is_a: CCO:F0003637 ! biotin-protein ligase activity [Term] id: CCO:F0000553 name: biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming))." [EC:6.3.4.11] synonym: "beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity" EXACT [EC:6.3.4.11] synonym: "biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity" EXACT [EC:6.3.4.11] synonym: "biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity" EXACT [EC:6.3.4.11] synonym: "biotin-methylcrotonoyl-CoA-carboxylase ligase activity" EXACT [EC:6.3.4.11] synonym: "biotin-methylcrotonoyl-CoA-carboxylase synthetase" BROAD [EC:6.3.4.11] synonym: "biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)" EXACT [EC:6.3.4.11] synonym: "holocarboxylase-synthetase activity" EXACT [EC:6.3.4.11] xref: EC:6.3.4.11 xref: GO:0004078 xref: MetaCyc:6.3.4.11-RXN is_a: CCO:F0003637 ! biotin-protein ligase activity [Term] id: CCO:F0000554 name: biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase)." [EC:6.3.4.9] synonym: "biotin--[methylmalonyl-CoA-carboxyltransferase] ligase activity" EXACT [EC:6.3.4.9] synonym: "biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase activity" EXACT [EC:6.3.4.9] synonym: "biotin--[methylmalonyl-CoA-carboxytransferase] synthetase activity" EXACT [EC:6.3.4.9] synonym: "biotin-[methylmalonyl-CoA-carboxyltransferase] ligase activity" EXACT [] synonym: "biotin-methylmalonyl coenzyme A carboxyltransferase synthetase activity" EXACT [EC:6.3.4.9] synonym: "biotin-methylmalonyl-CoA-carboxyltransferase ligase activity" EXACT [EC:6.3.4.9] synonym: "biotin-methylmalonyl-CoA-carboxyltransferase synthetase" BROAD [EC:6.3.4.9] synonym: "biotin-methylmalonyl-CoA-carboxytransferase ligase activity" EXACT [EC:6.3.4.9] synonym: "biotin-methylmalonyl-CoA-carboxytransferase synthetase activity" EXACT [EC:6.3.4.9] synonym: "biotin-transcarboxylase synthetase activity" EXACT [EC:6.3.4.9] synonym: "biotin:apomethylmalonyl-CoA:pyruvate carboxyltransferase ligase (AMP-forming)" EXACT [EC:6.3.4.9] synonym: "biotin:apomethylmalonyl-CoA:pyruvate carboxytransferase ligase (AMP-forming)" EXACT [EC:6.3.4.9] synonym: "methylmalonyl coenzyme A holotranscarboxylase synthetase activity" EXACT [EC:6.3.4.9] xref: EC:6.3.4.9 xref: GO:0004079 xref: MetaCyc:6.3.4.9-RXN is_a: CCO:F0003637 ! biotin-protein ligase activity [Term] id: CCO:F0000555 name: biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming))." [EC:6.3.4.10] synonym: "biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase activity" EXACT [EC:6.3.4.10] synonym: "biotin-propionyl coenzyme A carboxylase synthetase activity" EXACT [EC:6.3.4.10] synonym: "biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) ligase activity" EXACT [EC:6.3.4.10] synonym: "biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) synthetase activity" EXACT [EC:6.3.4.10] synonym: "biotin:apo-propanoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)" EXACT [EC:6.3.4.10] synonym: "holocarboxylase synthetase activity" EXACT [EC:6.3.4.10] synonym: "propionyl coenzyme A holocarboxylase synthetase activity" EXACT [EC:6.3.4.10] synonym: "propionyl-CoA holocarboxylase synthetase activity" EXACT [EC:6.3.4.10] xref: EC:6.3.4.10 xref: GO:0004080 xref: MetaCyc:6.3.4.10-RXN is_a: CCO:F0003637 ! biotin-protein ligase activity [Term] id: CCO:F0000556 name: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity namespace: molecular_function def: "Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate." [EC:3.6.1.17, PMID:4955726] subset: gosubset_prok synonym: "1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.17] synonym: "Ap(4)A hydrolase activity" BROAD [EC:3.6.1.17] synonym: "Ap(4)Aase activity" BROAD [EC:3.6.1.17] synonym: "Ap4A hydrolase activity" BROAD [EC:3.6.1.17] synonym: "Ap4Aase activity" BROAD [EC:3.6.1.17] synonym: "bis(5'-adenosyl)-tetraphosphatase activity" NARROW [EC:3.6.1.17] synonym: "bis(5'-guanosyl)-tetraphosphatase activity" NARROW [EC:3.6.1.17] synonym: "diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity" EXACT [EC:3.6.1.17] synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity" EXACT [EC:3.6.1.17] synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase" NARROW [] synonym: "diadenosine P1,P4-tetraphosphatase activity" EXACT [EC:3.6.1.17] synonym: "diadenosinetetraphosphatase (asymmetrical) activity" NARROW [EC:3.6.1.17] synonym: "diguanosinetetraphosphatase (asymmetrical) activity" NARROW [EC:3.6.1.17] synonym: "dinucleoside tetraphosphatase activity" EXACT [EC:3.6.1.17] synonym: "dinucleosidetetraphosphatase (asymmetrical) activity" EXACT [EC:3.6.1.17] synonym: "P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.17] xref: EC:3.6.1.17 xref: GO:0004081 xref: MetaCyc:3.6.1.17-RXN is_a: CCO:F0002141 ! bis(5'-nucleosyl)-tetraphosphatase activity [Term] id: CCO:F0000557 name: bisphosphoglycerate mutase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate." [EC:5.4.2.4] synonym: "2,3-bisphosphoglycerate mutase activity" EXACT [EC:5.4.2.4] synonym: "2,3-bisphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] synonym: "2,3-diphosphoglycerate mutase activity" EXACT [EC:5.4.2.4] synonym: "2,3-diphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] synonym: "2,3-diphosphoglyceromutase activity" EXACT [EC:5.4.2.4] synonym: "3-phospho-D-glycerate 1,2-phosphomutase activity" EXACT [EC:5.4.2.4] synonym: "biphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] synonym: "bisphosphoglycerate synthase activity" EXACT [EC:5.4.2.4] synonym: "bisphosphoglyceromutase" BROAD [EC:5.4.2.4] synonym: "BPGM activity" EXACT [EC:5.4.2.4] synonym: "diphosphoglycerate mutase activity" EXACT [EC:5.4.2.4] synonym: "diphosphoglyceric mutase activity" EXACT [EC:5.4.2.4] synonym: "diphosphoglyceromutase activity" EXACT [EC:5.4.2.4] synonym: "DPGM" RELATED [EC:5.4.2.4] synonym: "glycerate phosphomutase activity" EXACT [EC:5.4.2.4] xref: EC:5.4.2.4 xref: GO:0004082 xref: MetaCyc:BISPHOSPHOGLYCERATE-MUTASE-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0000558 name: bisphosphoglycerate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate." [EC:3.1.3.13, GOC:mah, PMID:18413611] synonym: "2,3-bisphosphoglycerate phosphatase activity" EXACT [EC:3.1.3.13] synonym: "2,3-diphosphoglycerate phosphatase activity" EXACT [EC:3.1.3.13] synonym: "2,3-diphosphoglyceric acid phosphatase activity" EXACT [EC:3.1.3.13] synonym: "diphosphoglycerate phosphatase activity" EXACT [EC:3.1.3.13] synonym: "glycerate-2,3-diphosphate phosphatase activity" EXACT [EC:3.1.3.13] xref: GO:0034416 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000559 name: branched-chain-amino-acid transaminase activity namespace: molecular_function def: "Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid. Includes catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate and anaologous reactions involving L-isoleucine and L-valine." [EC:2.6.1.42, GOC:mah] subset: gosubset_prok synonym: "branched-chain amino acid aminotransferase activity" EXACT [] synonym: "branched-chain amino acid-glutamate transaminase activity" EXACT [EC:2.6.1.42] synonym: "branched-chain aminotransferase activity" EXACT [EC:2.6.1.42] synonym: "branched-chain-amino-acid:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.42] synonym: "glutamate-branched-chain amino acid transaminase activity" EXACT [EC:2.6.1.42] synonym: "L-branched chain amino acid aminotransferase activity" EXACT [EC:2.6.1.42] synonym: "transaminase B activity" RELATED [EC:2.6.1.42] xref: EC:2.6.1.42 xref: GO:0004084 xref: MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN xref: Reactome:70697 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000560 name: butyryl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: butanoyl-CoA + ETF = 2-butenoyl-CoA + reduced ETF." [EC:1.3.99.2] subset: gosubset_prok synonym: "3-hydroxyacyl CoA reductase activity" EXACT [EC:1.3.99.2] synonym: "butanoyl-CoA:(acceptor) 2,3-oxidoreductase activity" EXACT [EC:1.3.99.2] synonym: "butanoyl-CoA:acceptor 2,3-oxidoreductase activity" EXACT [EC:1.3.99.2] synonym: "butyryl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.2] synonym: "butyryl dehydrogenase activity" EXACT [EC:1.3.99.2] synonym: "enoyl-coenzyme A reductase activity" EXACT [EC:1.3.99.2] synonym: "ethylene reductase activity" EXACT [EC:1.3.99.2] synonym: "short-chain acyl CoA dehydrogenase activity" EXACT [EC:1.3.99.2] synonym: "short-chain acyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.2] synonym: "short-chain-acyl-CoA dehydrogenase activity" RELATED [EC:1.3.99.2] synonym: "unsaturated acyl coenzyme A reductase activity" EXACT [EC:1.3.99.2] synonym: "unsaturated acyl-CoA reductase activity" RELATED [EC:1.3.99.2] xref: EC:1.3.99.2 xref: GO:0004085 xref: MetaCyc:BUTYRYL-COA-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0034 is_a: CCO:F0000480 ! acyl-CoA dehydrogenase activity [Term] id: CCO:F0000561 name: carbamoyl-phosphate synthase activity namespace: molecular_function def: "Catalysis of a reaction that results in the formation of carbamoyl phosphate." [EC:6.3.4.16, EC:6.3.5.5, GOC:mah] subset: gosubset_prok synonym: "carbamoyl phosphate synthase activity" EXACT [] xref: EC:6.3.-.- xref: GO:0004086 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0000562 name: carbamoyl-phosphate synthase (ammonia) activity namespace: molecular_function def: "Catalysis of the reaction: 2 ATP + NH3 + CO2 + H2O = 2 ADP + phosphate + carbamoyl phosphate." [EC:6.3.4.16] subset: gosubset_prok synonym: "carbamoyl phosphate synthase (ammonia) activity" EXACT [] synonym: "carbamoyl-phosphate synthetase (ammonia) activity" EXACT [EC:6.3.4.16] synonym: "carbamoyl-phosphate synthetase I activity" EXACT [EC:6.3.4.16] synonym: "carbamoylphosphate synthase (ammonia)" EXACT [EC:6.3.4.16] synonym: "carbamoylphosphate synthase activity" EXACT [EC:6.3.4.16] synonym: "carbamoylphosphate synthetase (ammonia) activity" EXACT [EC:6.3.4.16] synonym: "carbamylphosphate synthetase activity" EXACT [EC:6.3.4.16] synonym: "carbamylphosphate synthetase I" RELATED [EC:6.3.4.16] synonym: "carbmoylphosphate synthetase activity" EXACT [EC:6.3.4.16] synonym: "carbon-dioxide--ammonia ligase activity" EXACT [EC:6.3.4.16] synonym: "carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)" EXACT [EC:6.3.4.16] synonym: "CPS I activity" NARROW [EC:6.3.4.16] xref: EC:6.3.4.16 xref: GO:0004087 xref: MetaCyc:6.3.4.16-RXN xref: Reactome:7296 is_a: CCO:F0000561 ! carbamoyl-phosphate synthase activity [Term] id: CCO:F0000563 name: carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate." [EC:6.3.5.5] subset: gosubset_prok synonym: "carbamoyl phosphate synthase (glutamine-hydrolyzing) activity" EXACT [] synonym: "carbamoyl phosphate synthetase activity" EXACT [EC:6.3.5.5] synonym: "carbamoyl-phosphate synthase (glutamine-hydrolysing) activity" EXACT [EC:6.3.5.5] synonym: "carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity" EXACT [EC:6.3.5.5] synonym: "carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity" EXACT [EC:6.3.5.5] synonym: "carbamoylphosphate synthetase II activity" EXACT [EC:6.3.5.5] synonym: "carbamyl phosphate synthetase (glutamine) activity" EXACT [EC:6.3.5.5] synonym: "carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity" EXACT [EC:6.3.5.5] synonym: "CPS activity" EXACT [EC:6.3.5.5] synonym: "GD-CPSase activity" EXACT [EC:6.3.5.5] synonym: "glutamine-dependent carbamoyl-phosphate synthase activity" EXACT [EC:6.3.5.5] synonym: "glutamine-dependent carbamyl phosphate synthetase activity" EXACT [EC:6.3.5.5] synonym: "hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity" EXACT [EC:6.3.5.5] xref: EC:6.3.5.5 xref: GO:0004088 xref: MetaCyc:CARBPSYN-RXN xref: Reactome:7299 is_a: CCO:F0000561 ! carbamoyl-phosphate synthase activity is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0000564 name: carbonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: H2CO3 = CO2 + H2O." [EC:4.2.1.1] subset: gosubset_prok synonym: "anhydrase activity" EXACT [EC:4.2.1.1] synonym: "carbonate anhydrase activity" EXACT [EC:4.2.1.1] synonym: "carbonate hydro-lyase (carbon-dioxide-forming)" EXACT [EC:4.2.1.1] synonym: "carbonate hydro-lyase activity" EXACT [EC:4.2.1.1] synonym: "carbonic acid anhydrase activity" EXACT [EC:4.2.1.1] synonym: "carbonic anhydrase A" RELATED [EC:4.2.1.1] synonym: "carbonic anhydrase activity" EXACT [] synonym: "carbonic dehydratase activity" EXACT [EC:4.2.1.1] synonym: "carboxyanhydrase activity" EXACT [EC:4.2.1.1] xref: EC:4.2.1.1 xref: GO:0004089 xref: MetaCyc:CARBODEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000565 name: carbonyl reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+." [EC:1.1.1.184] subset: gosubset_prok synonym: "aldehyde reductase 1" RELATED [EC:1.1.1.184] synonym: "aldehyde reductase I activity" RELATED [EC:1.1.1.184] synonym: "ALR3" RELATED [EC:1.1.1.184] synonym: "carbonyl reductase activity" EXACT [EC:1.1.1.184] synonym: "NADPH-dependent carbonyl reductase activity" EXACT [EC:1.1.1.184] synonym: "NADPH2-dependent carbonyl reductase activity" EXACT [EC:1.1.1.184] synonym: "nonspecific NADPH-dependent carbonyl reductase activity" EXACT [EC:1.1.1.184] synonym: "prostaglandin 9-ketoreductase activity" NARROW [EC:1.1.1.184] synonym: "secondary-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.184] synonym: "xenobiotic ketone reductase activity" NARROW [EC:1.1.1.184] xref: EC:1.1.1.184 xref: GO:0004090 xref: MetaCyc:CARBONYL-REDUCTASE-(NADPH)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000566 name: carboxylesterase activity namespace: molecular_function def: "Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion." [EC:3.1.1.1] subset: gosubset_prok synonym: "Ali-esterase activity" RELATED [EC:3.1.1] synonym: "ali-esterase activity" EXACT [EC:3.1.1] synonym: "alpha-carboxylesterase activity" EXACT [EC:3.1.1] synonym: "B-esterase activity" RELATED [EC:3.1.1] synonym: "carboxyesterase activity" EXACT [EC:3.1.1] synonym: "carboxyl ester hydrolase activity" EXACT [EC:3.1.1] synonym: "carboxylate esterase activity" EXACT [EC:3.1.1] synonym: "carboxylic acid esterase activity" EXACT [] synonym: "carboxylic ester hydrolase activity" EXACT [] synonym: "carboxylic esterase activity" EXACT [EC:3.1.1] synonym: "carboxylic-ester hydrolase activity" EXACT [EC:3.1.1] synonym: "cocaine esterase activity" NARROW [EC:3.1.1] synonym: "esterase A" RELATED [EC:3.1.1] synonym: "esterase B" RELATED [EC:3.1.1] synonym: "nonspecific carboxylesterase activity" EXACT [EC:3.1.1] synonym: "procaine esterase activity" NARROW [EC:3.1.1] synonym: "serine esterase activity" EXACT [] synonym: "triacetin esterase" NARROW [EC:3.1.1] synonym: "vitamin A esterase" NARROW [EC:3.1.1] xref: EC:3.1.1 xref: EC:3.1.1.1 xref: GO:0004091 xref: GO:0004302 xref: GO:0004759 xref: GO:0016789 xref: MetaCyc:CARBOXYLESTERASE-RXN xref: UM-BBD_enzymeID:e0631 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0000567 name: carnitine O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + carnitine = CoA + O-acetylcarnitine." [EC:2.3.1.7] subset: gosubset_prok synonym: "acetyl-CoA-carnitine O-acetyltransferase activity" EXACT [EC:2.3.1.7] synonym: "acetyl-CoA:carnitine O-acetyltransferase activity" EXACT [EC:2.3.1.7] synonym: "acetylcarnitine transferase activity" EXACT [EC:2.3.1.7] synonym: "carnitine acetyl coenzyme A transferase activity" EXACT [EC:2.3.1.7] synonym: "carnitine acetylase activity" EXACT [EC:2.3.1.7] synonym: "carnitine acetyltransferase activity" EXACT [EC:2.3.1.7] synonym: "carnitine O-acetyltransferase I activity" NARROW [] synonym: "carnitine O-acetyltransferase II activity" NARROW [] synonym: "carnitine-acetyl-CoA transferase activity" EXACT [EC:2.3.1.7] synonym: "CATC" RELATED [EC:2.3.1.7] xref: EC:2.3.1.7 xref: GO:0004092 xref: GO:0004093 xref: GO:0004094 xref: MetaCyc:CARNITINE-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003129 ! carnitine O-acyltransferase activity is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0000568 name: carnitine O-palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine." [EC:2.3.1.21] synonym: "acylcarnitine transferase activity" EXACT [EC:2.3.1.21] synonym: "carnitine palmitoyltransferase activity" EXACT [EC:2.3.1.21] synonym: "carnitine palmitoyltransferase I" RELATED [EC:2.3.1.21] synonym: "carnitine palmitoyltransferase II" RELATED [EC:2.3.1.21] synonym: "carnitine palmitoyltransferase-A" RELATED [EC:2.3.1.21] synonym: "CPT" RELATED [EC:2.3.1.21] synonym: "CPT I (outer membrane carnitine palmitoyl transferase)" RELATED [EC:2.3.1.21] synonym: "CPT-A" RELATED [EC:2.3.1.21] synonym: "CPT-B" RELATED [EC:2.3.1.21] synonym: "CPTi" RELATED [EC:2.3.1.21] synonym: "CPTo" RELATED [EC:2.3.1.21] synonym: "L-carnitine palmitoyltransferase activity" EXACT [EC:2.3.1.21] synonym: "outer malonyl-CoA inhibitable carnitine palmitoyltransferase activity" EXACT [EC:2.3.1.21] synonym: "palmitoyl-CoA:L-carnitine O-palmitoyltransferase activity" EXACT [EC:2.3.1.21] synonym: "palmitoylcarnitine transferase activity" EXACT [EC:2.3.1.21] xref: EC:2.3.1.21 xref: GO:0004095 xref: MetaCyc:CARNITINE-O-PALMITOYLTRANSFERASE-RXN is_a: CCO:F0003129 ! carnitine O-acyltransferase activity is_a: CCO:F0003139 ! O-palmitoyltransferase activity [Term] id: CCO:F0000569 name: catalase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O." [EC:1.11.1.6] subset: gosubset_prok synonym: "bacterial catalase-peroxidase activity" NARROW [] synonym: "caperase activity" EXACT [EC:1.11.1.6] synonym: "CAT" RELATED [EC:1.11.1.6] synonym: "catalase reaction" EXACT [] synonym: "catalase-peroxidase activity" EXACT [EC:1.11.1.6] synonym: "equilase activity" EXACT [EC:1.11.1.6] synonym: "haem catalase activity" NARROW [] synonym: "heme catalase activity" NARROW [] synonym: "hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.6] synonym: "manganese catalase activity" NARROW [] synonym: "optidase activity" EXACT [EC:1.11.1.6] xref: EC:1.11.1.6 xref: GO:0004096 xref: GO:0016952 xref: GO:0016953 xref: MetaCyc:CATAL-RXN xref: Reactome:76029 xref: UM-BBD_enzymeID:e0834 is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0000570 name: catechol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O." [EC:1.10.3.1] subset: gosubset_prok synonym: "1,2-benzenediol:oxygen oxidoreductase activity" EXACT [EC:1.10.3.1] synonym: "catecholase" BROAD [EC:1.10.3.1] synonym: "diphenol oxidase activity" EXACT [EC:1.10.3.1] synonym: "dopa oxidase" BROAD [EC:1.10.3.1] synonym: "o-diphenol oxidoreductase" BROAD [EC:1.10.3.1] synonym: "o-diphenol:oxygen oxidoreductase" BROAD [EC:1.10.3.1] synonym: "o-diphenolase activity" EXACT [EC:1.10.3.1] synonym: "phenolase activity" BROAD [EC:1.10.3.1] synonym: "polyphenol oxidase activity" EXACT [EC:1.10.3.1] synonym: "pyrocatechol oxidase" BROAD [EC:1.10.3.1] synonym: "tyrosinase activity" BROAD [EC:1.10.3.1] xref: EC:1.10.3.1 xref: GO:0004097 xref: MetaCyc:CATECHOL-OXIDASE-RXN is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0000571 name: cerebroside-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + SO4(2-) (sulfate)." [EC:3.1.6.8] subset: gosubset_prok synonym: "arylsulfatase A activity" EXACT [EC:3.1.6.8] synonym: "cerebroside sulfate sulfatase activity" EXACT [EC:3.1.6.8] synonym: "cerebroside-3-sulfate 3-sulfohydrolase activity" EXACT [EC:3.1.6.8] synonym: "cerebroside-sulphatase activity" EXACT [] xref: EC:3.1.6.8 xref: GO:0004098 xref: MetaCyc:CEREBROSIDE-SULFATASE-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0000572 name: chitin deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: chitin + H2O = chitosan + acetate." [EC:3.5.1.41] subset: gosubset_prok synonym: "chitin amidohydrolase activity" EXACT [EC:3.5.1.41] xref: EC:3.5.1.41 xref: GO:0004099 xref: MetaCyc:CHITIN-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0000573 name: chitin synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1)." [EC:2.4.1.16] subset: gosubset_prok synonym: "chitin synthetase activity" EXACT [EC:2.4.1.16] synonym: "chitin-UDP acetyl-glucosaminyl transferase activity" EXACT [EC:2.4.1.16] synonym: "chitin-UDP N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.16] synonym: "chitin-uridine diphosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.16] synonym: "trans-N-acetylglucosaminosylase activity" EXACT [EC:2.4.1.16] synonym: "UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity" EXACT [EC:2.4.1.16] xref: EC:2.4.1.16 xref: GO:0004100 xref: MetaCyc:CHITIN-SYNTHASE-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0000574 name: choline O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + choline = CoA + O-acetylcholine." [EC:2.3.1.6] subset: gosubset_prok synonym: "acetyl-CoA:choline O-acetyltransferase activity" EXACT [EC:2.3.1.6] synonym: "CHOACTase activity" EXACT [EC:2.3.1.6] synonym: "choline acetylase activity" EXACT [EC:2.3.1.6] synonym: "choline acetyltransferase activity" EXACT [EC:2.3.1.6] xref: EC:2.3.1.6 xref: GO:0004102 xref: MetaCyc:CHOLINE-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0000575 name: choline kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + choline = ADP + O-phosphocholine." [EC:2.7.1.32] subset: gosubset_prok synonym: "ATP:choline phosphotransferase activity" EXACT [EC:2.7.1.32] synonym: "choline kinase (phosphorylating)" EXACT [EC:2.7.1.32] synonym: "choline phosphokinase activity" EXACT [EC:2.7.1.32] synonym: "choline-ethanolamine kinase activity" EXACT [EC:2.7.1.32] xref: EC:2.7.1.32 xref: GO:0004103 xref: MetaCyc:CHOLINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000576 name: cholinesterase activity namespace: molecular_function def: "Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion." [EC:3.1.1.8] subset: gosubset_prok synonym: "acylcholine acylhydrolase activity" EXACT [EC:3.1.1.8] synonym: "anticholineesterase activity" EXACT [EC:3.1.1.8] synonym: "benzoylcholinesterase activity" EXACT [EC:3.1.1.8] synonym: "BtChoEase activity" EXACT [EC:3.1.1.8] synonym: "butyrylcholine esterase activity" EXACT [EC:3.1.1.8] synonym: "butyrylcholinesterase activity" EXACT [EC:3.1.1.8] synonym: "choline esterase activity" EXACT [EC:3.1.1.8] synonym: "choline esterase II (unspecific) activity" EXACT [EC:3.1.1.8] synonym: "non-specific cholinesterase activity" EXACT [EC:3.1.1.8] synonym: "propionylcholinesterase activity" EXACT [EC:3.1.1.8] synonym: "pseudocholinesterase activity" EXACT [EC:3.1.1.8] xref: EC:3.1.1.8 xref: GO:0004104 xref: MetaCyc:CHOLINESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0000577 name: choline-phosphate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline." [EC:2.7.7.15] subset: gosubset_prok synonym: "CDP-choline pyrophosphorylase activity" EXACT [EC:2.7.7.15] synonym: "CDP-choline synthetase activity" EXACT [EC:2.7.7.15] synonym: "choline phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.15] synonym: "CTP-phosphocholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] synonym: "CTP:choline-phosphate cytidylyltransferase activity" EXACT [] synonym: "CTP:phosphocholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] synonym: "CTP:phosphorylcholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] synonym: "cytidine diphosphocholine pyrophosphorylase activity" EXACT [EC:2.7.7.15] synonym: "phosphocholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] synonym: "phosphorylcholine cytidylyltransferase activity" EXACT [EC:2.7.7.15] synonym: "phosphorylcholine transferase activity" EXACT [EC:2.7.7.15] synonym: "phosphorylcholine:CTP cytidylyltransferase activity" EXACT [EC:2.7.7.15] xref: EC:2.7.7.15 xref: GO:0004105 xref: MetaCyc:2.7.7.15-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000578 name: chorismate mutase activity namespace: molecular_function def: "Catalysis of the reaction: chorismate = prephenate." [EC:5.4.99.5] subset: gosubset_prok synonym: "chorismate pyruvatemutase activity" EXACT [EC:5.4.99.5] synonym: "hydroxyphenylpyruvate synthase activity" BROAD [EC:5.4.99.5] xref: EC:5.4.99.5 xref: GO:0004106 xref: MetaCyc:CHORISMATEMUT-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0000579 name: chorismate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate." [EC:4.2.3.5] subset: gosubset_prok synonym: "5-enolpyruvylshikimate-3-phosphate phospholyase activity" EXACT [EC:4.2.3.5] synonym: "5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)" EXACT [EC:4.2.3.5] synonym: "5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase activity" EXACT [EC:4.2.3.5] xref: EC:4.2.3.5 xref: GO:0004107 xref: MetaCyc:CHORISMATE-SYNTHASE-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0000580 name: citrate (Si)-synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA." [EC:2.3.3.1] comment: Note that this function was formerly EC:4.1.3.7. subset: gosubset_prok synonym: "(R)-citric synthase activity" EXACT [EC:2.3.3.1] synonym: "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]" RELATED [EC:2.3.3.1] synonym: "citrate condensing enzyme activity" EXACT [EC:2.3.3.1] synonym: "citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity" EXACT [EC:2.3.3.1] synonym: "citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)" EXACT [EC:2.3.3.1] synonym: "citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]" RELATED [EC:2.3.3.1] synonym: "citrate oxaloacetate-lyase, CoA-acetylating activity" EXACT [EC:2.3.3.1] synonym: "citrate synthase activity" BROAD [EC:2.3.3.1] synonym: "citrate synthetase activity" EXACT [EC:2.3.3.1] synonym: "citric synthase activity" EXACT [EC:2.3.3.1] synonym: "citric-condensing enzyme activity" EXACT [EC:2.3.3.1] synonym: "citrogenase activity" EXACT [EC:2.3.3.1] synonym: "condensing enzyme activity" BROAD [EC:2.3.3.1] synonym: "oxalacetic transacetase activity" EXACT [EC:2.3.3.1] synonym: "oxaloacetate transacetase activity" EXACT [EC:2.3.3.1] xref: EC:2.3.3.1 xref: GO:0004108 xref: MetaCyc:CITSYN-RXN xref: Reactome:8157 is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0000581 name: coproporphyrinogen oxidase activity namespace: molecular_function def: "Catalysis of the reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O." [EC:1.3.3.3] subset: gosubset_prok synonym: "coprogen oxidase activity" EXACT [] synonym: "coproporphyrinogen-III oxidase activity" EXACT [] synonym: "coproporphyrinogen:oxygen oxidoreductase (decarboxylating)" EXACT [EC:1.3.3.3] synonym: "coproporphyrinogenase activity" EXACT [] xref: EC:1.3.3.3 xref: GO:0004109 xref: MetaCyc:RXN0-1461 xref: Reactome:8160 is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0000582 name: corticosteroid side-chain-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al." [EC:5.3.1.21] synonym: "11-deoxycorticosterone aldose-ketose-isomerase activity" EXACT [EC:5.3.1.21] synonym: "11-deoxycorticosterone ketol-isomerase activity" EXACT [EC:5.3.1.21] xref: EC:5.3.1.21 xref: GO:0004110 xref: MetaCyc:CORTICOSTEROID-SIDE-CHAIN-ISOMERASE-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0000583 name: creatine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + creatine = ADP + phosphocreatine." [EC:2.7.3.2] synonym: "adenosine triphosphate-creatine transphosphorylase activity" EXACT [EC:2.7.3.2] synonym: "ATP:creatine N-phosphotransferase activity" EXACT [EC:2.7.3.2] synonym: "ATP:creatine phosphotransferase activity" EXACT [EC:2.7.3.2] synonym: "BB-CK" RELATED [EC:2.7.3.2] synonym: "CK" RELATED [EC:2.7.3.2] synonym: "CK-BB" RELATED [EC:2.7.3.2] synonym: "CK-MB" RELATED [EC:2.7.3.2] synonym: "CK-MM" RELATED [EC:2.7.3.2] synonym: "CKMiMi" RELATED [EC:2.7.3.2] synonym: "creatine phosphokinase activity" EXACT [EC:2.7.3.2] synonym: "creatine phosphotransferase activity" EXACT [EC:2.7.3.2] synonym: "MB-CK" RELATED [EC:2.7.3.2] synonym: "Mi-CK" RELATED [EC:2.7.3.2] synonym: "MiMi-CK" RELATED [EC:2.7.3.2] synonym: "MM-CK" RELATED [EC:2.7.3.2] synonym: "phosphocreatine kinase activity" EXACT [EC:2.7.3.2] xref: EC:2.7.3.2 xref: GO:0004111 xref: MetaCyc:CREATINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0000584 name: cyclic-nucleotide phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate." [GOC:mah] subset: gosubset_prok xref: EC:3.1.4.- xref: GO:0004112 is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0000585 name: 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate." [EC:3.1.4.37] subset: gosubset_prok synonym: "2',3'-cyclic AMP phosphodiesterase activity" EXACT [EC:3.1.4.37] synonym: "2',3'-cyclic nucleoside monophosphate phosphodiesterase" BROAD [EC:3.1.4.37] synonym: "2',3'-cyclic nucleotide 3'-phosphodiesterase activity" EXACT [] synonym: "2',3'-cyclic nucleotide 3'-phosphohydrolase activity" EXACT [EC:3.1.4.37] synonym: "2',3'-cyclic nucleotide phosphohydrolase" BROAD [EC:3.1.4.37] synonym: "2':3'-CNMP-3'-ase activity" EXACT [EC:3.1.4.37] synonym: "2':3'-cyclic nucleotide 3'-phosphodiesterase activity" EXACT [EC:3.1.4.37] synonym: "CNPase activity" EXACT [EC:3.1.4.37] synonym: "cyclic 2',3'-nucleotide 3'-phosphodiesterase activity" EXACT [EC:3.1.4.37] synonym: "cyclic 2',3'-nucleotide phosphodiesterase" BROAD [EC:3.1.4.37] synonym: "cyclic-CMP phosphodiesterase activity" NARROW [EC:3.1.4.37] synonym: "nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase activity" EXACT [EC:3.1.4.37] xref: EC:3.1.4.37 xref: GO:0004113 xref: MetaCyc:3.1.4.37-RXN is_a: CCO:F0000584 ! cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0000586 name: 3',5'-cyclic-nucleotide phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate." [EC:3.1.4.17] subset: gosubset_prok synonym: "3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "3',5' cyclic-nucleotide phosphodiesterase activity" EXACT [] synonym: "3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.17] synonym: "3',5'-cyclonucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "3',5'-nucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity" EXACT [EC:3.1.4.17] synonym: "3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.17] synonym: "cyclic 3',5'-mononucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "cyclic 3',5'-nucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "cyclic 3',5'-phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "cyclic 3',5-nucleotide monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "cyclic AMP phosphodiesterase activity" NARROW [EC:3.1.4.17] synonym: "cyclic nucleotide phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity" EXACT [EC:3.1.4.17] synonym: "nucleoside 3',5'-cyclic phosphate diesterase activity" EXACT [EC:3.1.4.17] synonym: "nucleoside-3',5-monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.17] synonym: "PDE" RELATED [EC:3.1.4.17] xref: EC:3.1.4.17 xref: GO:0004114 xref: MetaCyc:3.1.4.17-RXN is_a: CCO:F0000584 ! cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0000587 name: 3',5'-cyclic-AMP phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate." [GOC:ai] subset: gosubset_prok synonym: "3',5' cAMP-specific phosphodiesterase activity" EXACT [] synonym: "3',5'-cAMP-specific phosphodiesterase activity" EXACT [] synonym: "3',5'-cyclic-AMP-specific phosphodiesterase activity" EXACT [] synonym: "adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity" EXACT [] synonym: "cAMP-specific phosphodiesterase activity" EXACT [] synonym: "cyclic AMP-specific phosphodiesterase activity" EXACT [] xref: EC:3.1.4.- xref: GO:0004115 xref: Reactome:8212 is_a: CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0000588 name: calmodulin-dependent cyclic-nucleotide phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin." [GOC:mah] xref: EC:3.1.4.- xref: GO:0004117 xref: Reactome:8219 is_a: CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0000589 name: cGMP-stimulated cyclic-nucleotide phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP." [GOC:mah] xref: EC:3.1.4.- xref: GO:0004118 is_a: CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0000590 name: cGMP-inhibited cyclic-nucleotide phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP." [GOC:mah] xref: EC:3.1.4.- xref: GO:0004119 is_a: CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0000591 name: photoreceptor cyclic-nucleotide phosphodiesterase activity namespace: molecular_function def: "Catalysis of the hydrolysis of bonds in a cyclic nucleotide (nucleoside cyclic phosphate + H2O = nucleoside phosphate)." [EC:3.1.4.-] xref: EC:3.1.4.- xref: GO:0004120 is_a: CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0000592 name: cystathionine beta-lyase activity namespace: molecular_function def: "Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate." [EC:4.4.1.8] subset: gosubset_prok synonym: "beta C-S lyase activity" EXACT [EC:4.4.1.8] synonym: "beta-cystathionase activity" EXACT [EC:4.4.1.8] synonym: "cystathionine L-homocysteine-lyase (deaminating)" EXACT [EC:4.4.1.8] synonym: "cystine lyase activity" EXACT [EC:4.4.1.8] synonym: "L-cystathionine L-homocysteine-lyase (deaminating)" EXACT [EC:4.4.1.8] synonym: "L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.8] xref: EC:4.4.1.8 xref: GO:0004121 xref: GO:0008799 xref: MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0000593 name: cystathionine beta-synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O." [EC:4.2.1.22] subset: gosubset_prok synonym: "beta-thionase activity" EXACT [EC:4.2.1.22] synonym: "L-serine hydro-lyase (adding homocysteine)" EXACT [EC:4.2.1.22] synonym: "L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [EC:4.2.1.22] synonym: "methylcysteine synthase activity" EXACT [EC:4.2.1.22] synonym: "serine sulfhydrase activity" EXACT [EC:4.2.1.22] synonym: "serine sulfhydrylase activity" EXACT [EC:4.2.1.22] xref: EC:4.2.1.22 xref: GO:0004122 xref: MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000594 name: cystathionine gamma-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate." [EC:4.4.1.1] subset: gosubset_prok synonym: "cystalysin" RELATED [EC:4.4.1.1] synonym: "cystathionase activity" EXACT [EC:4.4.1.1] synonym: "cystathioninase activity" EXACT [EC:4.4.1.1] synonym: "cysteine desulfhydrase activity" EXACT [] synonym: "cystine desulfhydrase activity" EXACT [EC:4.4.1.1] synonym: "gamma-CTL" RELATED [EC:4.4.1.1] synonym: "gamma-cystathionase activity" EXACT [EC:4.4.1.1] synonym: "homoserine deaminase activity" EXACT [EC:4.4.1.1] synonym: "homoserine deaminase-cystathionase activity" EXACT [EC:4.4.1.1] synonym: "homoserine dehydratase activity" EXACT [EC:4.4.1.1] synonym: "L-cystathionine cysteine-lyase (deaminating)" EXACT [EC:4.4.1.1] synonym: "L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)" EXACT [EC:4.4.1.1] xref: EC:4.4.1.1 xref: GO:0004123 xref: GO:0016225 xref: MetaCyc:CYSTAGLY-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0000595 name: cysteine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O3-acetyl-L-serine + H2S = L-cysteine + acetate." [EC:4.2.99.8] comment: Note that this function was formerly 4.2.99.8. subset: gosubset_prok synonym: "3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.47] synonym: "acetylserine sulfhydrylase activity" EXACT [EC:2.5.1.47] synonym: "cysteine synthetase activity" EXACT [EC:2.5.1.47] synonym: "O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity" EXACT [EC:2.5.1.47] synonym: "O-acetyl-L-serine sulfhydrylase activity" EXACT [EC:2.5.1.47] synonym: "O-acetyl-L-serine sulfohydrolase activity" EXACT [EC:2.5.1.47] synonym: "O-acetylserine (thiol)-lyase A activity" NARROW [EC:2.5.1.47] synonym: "O-acetylserine (thiol)-lyase activity" EXACT [EC:2.5.1.47] synonym: "O-acetylserine sulfhydrylase activity" EXACT [EC:2.5.1.47] synonym: "O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)" EXACT [EC:2.5.1.47] synonym: "O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.47] synonym: "OAS sulfhydrylase activity" EXACT [EC:2.5.1.47] xref: EC:2.5.1.47 xref: GO:0004124 xref: MetaCyc:ACSERLY-RXN is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0000596 name: L-seryl-tRNASec selenium transferase activity namespace: molecular_function def: "Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate." [EC:2.9.1.1] subset: gosubset_prok synonym: "cysteinyl-tRNA(Sec)-selenium transferase activity" EXACT [EC:2.9.1.1] synonym: "cysteinyl-tRNA(Sel)-selenium transferase activity" EXACT [EC:2.9.1.1] synonym: "cysteinyl-tRNA(Ser) selenium transferase activity" EXACT [] synonym: "cysteinyl-tRNASec-selenium transferase activity" EXACT [EC:2.9.1.1] synonym: "cysteinyl-tRNASel-selenium transferase activity" EXACT [EC:2.9.1.1] synonym: "L-selenocysteinyl-tRNA(Sec) synthase activity" EXACT [EC:2.9.1.1] synonym: "L-selenocysteinyl-tRNA(Sel) synthase activity" EXACT [EC:2.9.1.1] synonym: "L-selenocysteinyl-tRNASec synthase activity" EXACT [EC:2.9.1.1] synonym: "L-selenocysteinyl-tRNASel synthase activity" EXACT [EC:2.9.1.1] synonym: "L-seryl-tRNA(Ser) selenium transferase activity" EXACT [] synonym: "selenocysteine synthase activity" EXACT [] synonym: "selenocysteinyl-tRNA(Ser) synthase activity" EXACT [] synonym: "selenophosphate:L-seryl-tRNASec selenium transferase activity" EXACT [EC:2.9.1.1] xref: EC:2.9.1.1 xref: GO:0004125 xref: MetaCyc:2.9.1.1-RXN is_a: CCO:F0003358 ! selenotransferase activity [Term] id: CCO:F0000597 name: cytidine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: cytidine + H2O = uridine + NH3." [EC:3.5.4.5] subset: gosubset_prok synonym: "cytidine aminohydrolase activity" EXACT [EC:3.5.4.5] synonym: "cytosine nucleoside deaminase activity" EXACT [EC:3.5.4.5] xref: EC:3.5.4.5 xref: GO:0004126 xref: MetaCyc:CYTIDEAM2-RXN xref: Reactome:8270 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000598 name: cytidylate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP." [EC:2.7.4.14] subset: gosubset_prok synonym: "ATP:CMP phosphotransferase activity" EXACT [EC:2.7.4.14] synonym: "ATP:UMP-CMP phosphotransferase activity" EXACT [EC:2.7.4.14] synonym: "CMP kinase activity" NARROW [EC:2.7.4.14] synonym: "CTP:CMP phosphotransferase activity" EXACT [EC:2.7.4.14] synonym: "cytidine monophosphate kinase activity" EXACT [EC:2.7.4.14] synonym: "dCMP kinase activity" NARROW [EC:2.7.4.14] synonym: "deoxycytidine monophosphokinase activity" EXACT [EC:2.7.4.14] synonym: "deoxycytidylate kinase activity" BROAD [EC:2.7.4.14] synonym: "pyrimidine nucleoside monophosphate kinase activity" EXACT [EC:2.7.4.14] synonym: "UMP-CMP kinase activity" EXACT [EC:2.7.4.14] xref: EC:2.7.4.14 xref: GO:0004127 xref: MetaCyc:CMPKI-RXN is_a: CCO:F0004124 ! nucleotide kinase activity [Term] id: CCO:F0000599 name: cytochrome-b5 reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5)." [EC:1.6.2.2, ISBN:0198547684] synonym: "cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] synonym: "dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] synonym: "NADH 5alpha-reductase activity" EXACT [EC:1.6.2.2] synonym: "NADH-cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] synonym: "NADH-cytochrome-b5 reductase activity" EXACT [EC:1.6.2.2] synonym: "NADH-ferricytochrome b5 oxidoreductase activity" EXACT [EC:1.6.2.2] synonym: "NADH:ferricytochrome-b5 oxidoreductase activity" EXACT [EC:1.6.2.2] synonym: "reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity" EXACT [EC:1.6.2.2] xref: EC:1.6.2.2 xref: GO:0004128 xref: MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN is_a: CCO:F0003251 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor [Term] id: CCO:F0000600 name: cytochrome-c oxidase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1] subset: gosubset_prok synonym: "aa3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] synonym: "ba3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] synonym: "caa3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] synonym: "cbb3-type cytochrome c oxidase" NARROW [EC:1.9.3.1] synonym: "complex IV (mitochondrial electron transport) activity" RELATED [EC:1.9.3.1] synonym: "cytochrome a3 activity" NARROW [EC:1.9.3.1] synonym: "cytochrome aa3 activity" NARROW [EC:1.9.3.1] synonym: "cytochrome oxidase activity" RELATED [EC:1.9.3.1] synonym: "ferrocytochrome c oxidase" NARROW [EC:1.9.3.1] synonym: "ferrocytochrome-c:oxygen oxidoreductase" NARROW [EC:1.9.3.1] synonym: "indophenol oxidase" NARROW [EC:1.9.3.1] synonym: "indophenolase" NARROW [EC:1.9.3.1] synonym: "NADH cytochrome c oxidase" EXACT [EC:1.9.3.1] synonym: "warburg's respiratory enzyme activity" RELATED [EC:1.9.3.1] xref: EC:1.9.3.1 xref: GO:0004129 xref: MetaCyc:CYTOCHROME-C-OXIDASE-RXN xref: Reactome:8283 is_a: CCO:F0002522 ! heme-copper terminal oxidase activity is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity is_a: CCO:F0003268 ! oxidoreductase activity, acting on heme group of donors, oxygen as acceptor [Term] id: CCO:F0000601 name: cytochrome-c peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 ferrocytochrome c + H2O2 = 2 ferricytochrome c + 2 H2O." [EC:1.11.1.5] subset: gosubset_prok synonym: "apocytochrome c peroxidase activity" EXACT [EC:1.11.1.5] synonym: "cytochrome c peroxidase activity" EXACT [EC:1.11.1.5] synonym: "cytochrome c-551 peroxidase activity" EXACT [EC:1.11.1.5] synonym: "cytochrome c-H2O oxidoreductase activity" EXACT [EC:1.11.1.5] synonym: "cytochrome peroxidase activity" EXACT [EC:1.11.1.5] synonym: "ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.5] synonym: "mesocytochrome c peroxidase azide" RELATED [EC:1.11.1.5] synonym: "mesocytochrome c peroxidase cyanate" RELATED [EC:1.11.1.5] synonym: "mesocytochrome c peroxidase cyanide" RELATED [EC:1.11.1.5] xref: EC:1.11.1.5 xref: GO:0004130 xref: MetaCyc:CYTOCHROME-C-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0000602 name: cytosine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: cytosine + H2O = uracil + NH3." [EC:3.5.4.1] subset: gosubset_prok synonym: "cytosine aminohydrolase activity" EXACT [EC:3.5.4.1] synonym: "isocytosine deaminase activity" EXACT [EC:3.5.4.1] xref: EC:3.5.4.1 xref: GO:0004131 xref: MetaCyc:CYTDEAM-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000603 name: dCMP deaminase activity namespace: molecular_function def: "Catalysis of the reaction: dCMP + H2O = dUMP + NH3." [EC:3.5.4.12] subset: gosubset_prok synonym: "dCMP aminohydrolase activity" EXACT [EC:3.5.4.12] synonym: "deoxy-CMP-deaminase activity" EXACT [EC:3.5.4.12] synonym: "deoxycytidine monophosphate deaminase activity" EXACT [EC:3.5.4.12] synonym: "deoxycytidine-5'-monophosphate aminohydrolase activity" EXACT [EC:3.5.4.12] synonym: "deoxycytidine-5'-phosphate deaminase activity" EXACT [EC:3.5.4.12] synonym: "deoxycytidylate aminohydrolase activity" EXACT [EC:3.5.4.12] synonym: "deoxycytidylate deaminase activity" EXACT [EC:3.5.4.12] xref: EC:3.5.4.12 xref: GO:0004132 xref: MetaCyc:DCMP-DEAMINASE-RXN xref: Reactome:8340 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000604 name: glycogen debranching enzyme activity namespace: molecular_function def: "Catalysis of the cleavage of branch points in branched glycogen polymers." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0004133 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0000605 name: 4-alpha-glucanotransferase activity namespace: molecular_function def: "Catalysis of the transfer of a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan." [EC:2.4.1.25] subset: gosubset_prok synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity" EXACT [EC:2.4.1.25] synonym: "amylomaltase activity" EXACT [EC:2.4.1.25] synonym: "D-enzyme activity" RELATED [EC:2.4.1.25] synonym: "debranching enzyme maltodextrin glycosyltransferase activity" EXACT [EC:2.4.1.25] synonym: "dextrin glycosyltransferase activity" RELATED [EC:2.4.1.25] synonym: "dextrin transglycosylase activity" EXACT [EC:2.4.1.25] synonym: "disproportionating enzyme activity" RELATED [EC:2.4.1.25] synonym: "oligo-1,4-1,4-glucantransferase activity" EXACT [EC:2.4.1.25] xref: EC:2.4.1.25 xref: GO:0004134 xref: MetaCyc:2.4.1.25-RXN xref: Reactome:8344 is_a: CCO:F0000604 ! glycogen debranching enzyme activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0000606 name: amylo-alpha-1,6-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the 1,6 glycosidic linkages present." [EC:3.2.1.33, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "amylo-1,6-glucosidase activity" EXACT [] synonym: "amylopectin 1,6-glucosidase activity" EXACT [EC:3.2.1.33] synonym: "dextrin 6-alpha-D-glucosidase activity" RELATED [EC:3.2.1.33] synonym: "dextrin-1,6-glucosidase activity" EXACT [EC:3.2.1.33] synonym: "glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity" EXACT [EC:3.2.1.33] xref: EC:3.2.1.33 xref: GO:0004135 xref: MetaCyc:3.2.1.33-RXN xref: Reactome:8347 is_a: CCO:F0000604 ! glycogen debranching enzyme activity is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0000607 name: deoxyadenosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + deoxyadenosine = ADP + dAMP." [EC:2.7.1.76] subset: gosubset_prok synonym: "ATP:deoxyadenosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.76] synonym: "deoxyadenosine kinase (phosphorylating)" EXACT [EC:2.7.1.76] synonym: "purine-deoxyribonucleoside kinase activity" EXACT [EC:2.7.1.76] xref: EC:2.7.1.76 xref: GO:0004136 xref: MetaCyc:DEOXYADENOSINE-KINASE-RXN is_a: CCO:F0004072 ! deoxynucleoside kinase activity [Term] id: CCO:F0000608 name: deoxycytidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP." [EC:2.7.1.74] subset: gosubset_prok synonym: "2'-deoxycytidine kinase activity" EXACT [EC:2.7.1.74] synonym: "Ara-C kinase activity" EXACT [EC:2.7.1.74] synonym: "arabinofuranosylcytosine kinase activity" EXACT [EC:2.7.1.74] synonym: "deoxycytidine kinase (phosphorylating)" EXACT [EC:2.7.1.74] synonym: "deoxycytidine-cytidine kinase activity" EXACT [EC:2.7.1.74] synonym: "NTP:deoxycytidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.74] xref: EC:2.7.1.74 xref: GO:0004137 xref: MetaCyc:DEOXYCYTIDINE-KINASE-RXN is_a: CCO:F0004072 ! deoxynucleoside kinase activity [Term] id: CCO:F0000609 name: deoxyguanosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + deoxyguanosine = ADP + dGMP." [EC:2.7.1.113] subset: gosubset_prok synonym: "(dihydroxypropoxymethyl)guanine kinase activity" EXACT [EC:2.7.1.113] synonym: "2'-deoxyguanosine kinase activity" EXACT [EC:2.7.1.113] synonym: "ATP:deoxyguanosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.113] synonym: "deoxyguanosine kinase (phosphorylating)" EXACT [EC:2.7.1.113] synonym: "NTP-deoxyguanosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.113] xref: EC:2.7.1.113 xref: GO:0004138 xref: MetaCyc:DEOXYGUANOSINE-KINASE-RXN is_a: CCO:F0004072 ! deoxynucleoside kinase activity [Term] id: CCO:F0000610 name: deoxyribose-phosphate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde." [EC:4.1.2.4] subset: gosubset_prok synonym: "2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)" EXACT [EC:4.1.2.4] synonym: "2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity" EXACT [EC:4.1.2.4] synonym: "2-deoxyribose-5-phosphate aldolase activity" EXACT [EC:4.1.2.4] synonym: "deoxyriboaldolase activity" RELATED [EC:4.1.2.4] synonym: "deoxyribose-5-phosphate aldolase activity" EXACT [EC:4.1.2.4] synonym: "phosphodeoxyriboaldolase activity" EXACT [EC:4.1.2.4] xref: EC:4.1.2.4 xref: GO:0004139 xref: MetaCyc:DEOXYRIBOSE-P-ALD-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0000611 name: dephospho-CoA kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + dephospho-CoA = ADP + CoA." [EC:2.7.1.24] subset: gosubset_prok synonym: "3'-dephospho-CoA kinase activity" EXACT [EC:2.7.1.24] synonym: "ATP:dephospho-CoA 3'-phosphotransferase activity" EXACT [EC:2.7.1.24] synonym: "dephosphocoenzyme A kinase (phosphorylating)" EXACT [EC:2.7.1.24] synonym: "dephosphocoenzyme A kinase activity" RELATED [EC:2.7.1.24] xref: EC:2.7.1.24 xref: GO:0004140 xref: MetaCyc:DEPHOSPHOCOAKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000612 name: dethiobiotin synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin." [EC:6.3.3.3] subset: gosubset_prok synonym: "7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.3] synonym: "desthiobiotin synthase activity" EXACT [EC:6.3.3.3] synonym: "DTB synthetase activity" EXACT [EC:6.3.3.3] xref: EC:6.3.3.3 xref: GO:0004141 xref: MetaCyc:DETHIOBIOTIN-SYN-RXN is_a: CCO:F0003441 ! cyclo-ligase activity [Term] id: CCO:F0000613 name: diacylglycerol cholinephosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine." [EC:2.7.8.2] synonym: "1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "1-alkyl-2-acetylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "alkylacylglycerol choline phosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "alkylacylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "CDP-choline diglyceride phosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "cholinephosphotransferase activity" RELATED [EC:2.7.8.2] synonym: "CPT" RELATED [EC:2.7.8.2] synonym: "cytidine diphosphocholine glyceride transferase activity" EXACT [EC:2.7.8.2] synonym: "cytidine diphosphorylcholine diglyceride transferase activity" EXACT [EC:2.7.8.2] synonym: "diacylglycerol choline phosphotransferase activity" EXACT [EC:2.7.8.2] synonym: "phosphocholine diacylglyceroltransferase activity" EXACT [EC:2.7.8.2] synonym: "phosphorylcholine--glyceride transferase activity" EXACT [EC:2.7.8.2] synonym: "sn-1,2-diacylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.2] xref: EC:2.7.8.2 xref: GO:0004142 xref: MetaCyc:2.7.8.2-RXN is_a: CCO:F0003607 ! CDP-alcohol phosphatidyltransferase activity [Term] id: CCO:F0000614 name: diacylglycerol kinase activity namespace: molecular_function def: "Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol 3-phosphate." [EC:2.7.1.107, GOC:elh] subset: gosubset_prok synonym: "1,2-diacylglycerol kinase (phosphorylating)" EXACT [EC:2.7.1.107] synonym: "1,2-diacylglycerol kinase activity" EXACT [EC:2.7.1.107] synonym: "arachidonoyl-specific diacylglycerol kinase activity" EXACT [EC:2.7.1.107] synonym: "ATP:1,2-diacylglycerol 3-phosphotransferase activity" NARROW [EC:2.7.1.107] synonym: "ATP:diacylglycerol phosphotransferase activity" NARROW [EC:2.7.1.107] synonym: "CTP:diacylglycerol kinase activity" NARROW [] synonym: "DG kinase activity" EXACT [EC:2.7.1.107] synonym: "DGK activity" EXACT [EC:2.7.1.107] synonym: "diacylglycerol:ATP kinase activity" NARROW [EC:2.7.1.107] synonym: "diglyceride kinase activity" EXACT [EC:2.7.1.107] synonym: "sn-1,2-diacylglycerol kinase activity" EXACT [EC:2.7.1.107] xref: EC:2.7.1.107 xref: GO:0004143 xref: MetaCyc:DIACYLGLYKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000615 name: diacylglycerol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol." [EC:2.3.1.20] subset: gosubset_prok synonym: "1,2-diacylglycerol acyltransferase activity" EXACT [EC:2.3.1.20] synonym: "acyl-CoA:1,2-diacylglycerol O-acyltransferase activity" EXACT [EC:2.3.1.20] synonym: "diacylglycerol acyltransferase activity" EXACT [EC:2.3.1.20] synonym: "diglyceride acyltransferase activity" EXACT [EC:2.3.1.20] synonym: "diglyceride O-acyltransferase activity" EXACT [EC:2.3.1.20] synonym: "palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity" EXACT [EC:2.3.1.20] xref: EC:2.3.1.20 xref: GO:0004144 xref: MetaCyc:DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN xref: Reactome:8383 is_a: CCO:F0003134 ! acylglycerol O-acyltransferase activity [Term] id: CCO:F0000616 name: diamine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine." [EC:2.3.1.57] subset: gosubset_prok synonym: "acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity" EXACT [EC:2.3.1.57] synonym: "acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity" NARROW [] synonym: "diamine acetyltransferase activity" EXACT [] synonym: "putrescine (diamine)-acetylating enzyme activity" NARROW [] synonym: "putrescine acetylase activity" NARROW [EC:2.3.1.57] synonym: "putrescine acetyltransferase activity" NARROW [EC:2.3.1.57] synonym: "putrescine N-acetyltransferase activity" NARROW [EC:2.3.1.57] synonym: "spermidine acetyltransferase activity" NARROW [EC:2.3.1.57] synonym: "spermidine N(1)-acetyltransferase activity" NARROW [EC:2.3.1.57] synonym: "spermidine N1-acetyltransferase activity" EXACT [EC:2.3.1.57] synonym: "spermidine/spermine N1-acetyltransferase activity" EXACT [EC:2.3.1.57] synonym: "spermine acetyltransferase" NARROW [] synonym: "spermine N(1)-acetyltransferase" NARROW [] synonym: "spermine N-acetyltransferase" RELATED [] xref: EC:2.3.1.57 xref: GO:0004145 xref: MetaCyc:DIAMACTRANS-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0000617 name: dihydrofolate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+." [EC:1.5.1.3] subset: gosubset_prok synonym: "5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.3] synonym: "7,8-dihydrofolate reductase activity" EXACT [EC:1.5.1.3] synonym: "DHFR" RELATED [EC:1.5.1.3] synonym: "dihydrofolate reductase:thymidylate synthase activity" EXACT [EC:1.5.1.3] synonym: "dihydrofolate reduction" EXACT [] synonym: "dihydrofolic acid reductase activity" EXACT [EC:1.5.1.3] synonym: "dihydrofolic reductase activity" EXACT [EC:1.5.1.3] synonym: "folic acid reductase activity" EXACT [EC:1.5.1.3] synonym: "folic reductase activity" EXACT [EC:1.5.1.3] synonym: "NADPH-dihydrofolate reductase activity" EXACT [EC:1.5.1.3] synonym: "pteridine reductase:dihydrofolate reductase activity" EXACT [EC:1.5.1.3] synonym: "tetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.3] synonym: "thymidylate synthetase-dihydrofolate reductase activity" EXACT [EC:1.5.1.3] xref: EC:1.5.1.3 xref: GO:0004146 xref: MetaCyc:DIHYDROFOLATEREDUCT-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000618 name: dihydrolipoamide branched chain acyltransferase activity namespace: molecular_function subset: gosubset_prok synonym: "dihydrolipoamide branched chain transacylase activity" EXACT [] xref: EC:2.3.1.- xref: GO:0004147 xref: Reactome:8394 is_a: CCO:F0004452 ! dihydrolipoamide S-acyltransferase activity [Term] id: CCO:F0000619 name: dihydrolipoyl dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+." [EC:1.8.1.4] subset: gosubset_prok synonym: "dehydrolipoate dehydrogenase activity" EXACT [EC:1.8.1.4] synonym: "diaphorase activity" EXACT [EC:1.8.1.4] synonym: "dihydrolipoamide dehydrogenase activity" EXACT [EC:1.8.1.4] synonym: "dihydrolipoamide reduction" RELATED [EC:1.8.1.4] synonym: "dihydrolipoamide:NAD+ oxidoreductase" EXACT [EC:1.8.1.4] synonym: "dihydrolipoic dehydrogenase activity" EXACT [EC:1.8.1.4] synonym: "dihydrolipoylprotein reduction" RELATED [EC:1.8.1.4] synonym: "dihydrothioctic dehydrogenase activity" EXACT [EC:1.8.1.4] synonym: "E3 component of alpha-ketoacid dehydrogenase complexes activity" RELATED [EC:1.8.1.4] synonym: "glycine-cleavage system L-protein activity" RELATED [EC:1.8.1.4] synonym: "L-protein activity" RELATED [EC:1.8.1.4] synonym: "LDP-Glc activity" NARROW [EC:1.8.1.4] synonym: "LDP-Val activity" NARROW [EC:1.8.1.4] synonym: "lipoamide dehydrogenase (NADH) activity" EXACT [EC:1.8.1.4] synonym: "lipoamide oxidoreductase (NADH) activity" EXACT [EC:1.8.1.4] synonym: "lipoamide reductase (NADH) activity" EXACT [EC:1.8.1.4] synonym: "lipoamide reductase activity" EXACT [EC:1.8.1.4] synonym: "lipoate dehydrogenase activity" EXACT [EC:1.8.1.4] synonym: "lipoic acid dehydrogenase activity" EXACT [EC:1.8.1.4] synonym: "lipoyl dehydrogenase activity" EXACT [EC:1.8.1.4] synonym: "protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase" EXACT [EC:1.8.1.4] synonym: "protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase" EXACT [EC:1.8.1.4] xref: EC:1.8.1.4 xref: GO:0004148 xref: MetaCyc:DIHYDLIPOXN-RXN xref: Reactome:8399 is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000620 name: dihydrolipoyllysine-residue succinyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide." [EC:2.3.1.61] subset: gosubset_prok synonym: "dihydrolipoamide S-succinyltransferase activity" EXACT [] synonym: "dihydrolipoamide succinyltransferase activity" EXACT [EC:2.3.1.61] synonym: "dihydrolipoic transsuccinylase activity" EXACT [EC:2.3.1.61] synonym: "dihydrolipolyl transsuccinylase activity" EXACT [EC:2.3.1.61] synonym: "dihydrolipoyl transsuccinylase activity" EXACT [EC:2.3.1.61] synonym: "enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity" EXACT [EC:2.3.1.61] synonym: "lipoate succinyltransferase (Escherichia coli) activity" EXACT [EC:2.3.1.61] synonym: "lipoate succinyltransferase activity" EXACT [EC:2.3.1.61] synonym: "lipoic transsuccinylase activity" EXACT [EC:2.3.1.61] synonym: "lipoyl transsuccinylase activity" EXACT [EC:2.3.1.61] synonym: "succinyl-CoA:dihydrolipoamide S-succinyltransferase activity" EXACT [EC:2.3.1.61] synonym: "succinyl-CoA:dihydrolipoate S-succinyltransferase activity" EXACT [EC:2.3.1.61] synonym: "succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity" EXACT [EC:2.3.1.61] synonym: "succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity" EXACT [EC:2.3.1.61] xref: EC:2.3.1.61 xref: GO:0004149 xref: MetaCyc:DIHYDLIPSUCCTRANS-RXN xref: Reactome:8404 is_a: CCO:F0003326 ! S-succinyltransferase activity [Term] id: CCO:F0000621 name: dihydroneopterin aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde." [EC:4.1.2.25] subset: gosubset_prok synonym: "2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming)" EXACT [EC:4.1.2.25] synonym: "2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity" EXACT [EC:4.1.2.25] xref: EC:4.1.2.25 xref: GO:0004150 xref: MetaCyc:H2NEOPTERINALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0000622 name: dihydroorotase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate." [EC:3.5.2.3] subset: gosubset_prok synonym: "(S)-dihydroorotate amidohydrolase activity" EXACT [EC:3.5.2.3] synonym: "carbamoylaspartic dehydrase activity" EXACT [EC:3.5.2.3] synonym: "DHOase activity" EXACT [EC:3.5.2.3] synonym: "dihydroorotate hydrolase activity" EXACT [EC:3.5.2.3] xref: EC:3.5.2.3 xref: GO:0004151 xref: MetaCyc:DIHYDROOROT-RXN xref: Reactome:8410 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0000623 name: dihydroorotate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-dihydroorotate + acceptor = orotate + reduced acceptor." [EC:1.3.99.11] subset: gosubset_prok synonym: "(DHO) dehydrogenase activity" RELATED [EC:1.3.3.1] synonym: "(S)-dihydroorotate:(acceptor) oxidoreductase activity" EXACT [EC:1.3.99.11] synonym: "(S)-dihydroorotate:acceptor oxidoreductase activity" EXACT [EC:1.3.99.11] synonym: "DHOdehase activity" EXACT [EC:1.3.3.1] synonym: "dihydoorotic acid dehydrogenase activity" EXACT [EC:1.3.3.1] synonym: "dihydroorotate:ubiquinone oxidoreductase activity" NARROW [EC:1.3.99.11] xref: EC:1.3.99.11 xref: GO:0004152 xref: MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN xref: Reactome:8412 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0000624 name: dihydropterin deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 7,8-dihydropterin + H20 = 7,8-dihydrolumazine + NH3." [GOC:jl, ISSN:05829879] xref: GO:0004153 is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000625 name: dihydropterin oxidase activity namespace: molecular_function def: "Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + H2O2." [GOC:mah, PMID:1745247, PMID:6815189] xref: EC:1.5.3.- xref: GO:0004154 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0000626 name: 6,7-dihydropteridine reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine." [EC:1.5.1.34] comment: Note that this function was formerly EC:1.6.99.7. subset: gosubset_prok synonym: "5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity" EXACT [EC:1.5.1.34] synonym: "5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity" EXACT [EC:1.5.1.34] synonym: "6,7-dihydropteridine:NAD(P)H oxidoreductase activity" EXACT [EC:1.5.1.34] synonym: "DHPR activity" EXACT [EC:1.5.1.34] synonym: "dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity" EXACT [EC:1.5.1.34] synonym: "dihydropteridine reductase (NADH) activity" EXACT [EC:1.5.1.34] synonym: "dihydropteridine reductase activity" EXACT [] synonym: "dihydropteridine reduction" RELATED [] synonym: "NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity" EXACT [EC:1.5.1.34] synonym: "NAD(P)H2:6,7-dihydropteridine oxidoreductase activity" EXACT [EC:1.5.1.34] synonym: "NADH-dihydropteridine reductase activity" EXACT [EC:1.5.1.34] synonym: "NADPH-dihydropteridine reductase activity" EXACT [EC:1.5.1.34] synonym: "NADPH-specific dihydropteridine reductase activity" EXACT [EC:1.5.1.34] xref: EC:1.5.1.34 xref: GO:0004155 xref: MetaCyc:1.5.1.34-RXN xref: Reactome:8421 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000627 name: dihydropteroate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate." [EC:2.5.1.15] subset: gosubset_prok synonym: "(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity" EXACT [EC:2.5.1.15] synonym: "2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity" EXACT [EC:2.5.1.15] synonym: "7,8-dihydropteroate synthase activity" EXACT [EC:2.5.1.15] synonym: "7,8-dihydropteroate synthetase activity" EXACT [EC:2.5.1.15] synonym: "7,8-dihydropteroic acid synthetase activity" EXACT [EC:2.5.1.15] synonym: "DHPS activity" EXACT [EC:2.5.1.15] synonym: "dihydropteroate diphosphorylase activity" EXACT [EC:2.5.1.15] synonym: "dihydropteroate pyrophosphorylase activity" EXACT [EC:2.5.1.15] synonym: "dihydropteroate synthetase activity" EXACT [EC:2.5.1.15] synonym: "dihydropteroic synthetase activity" EXACT [EC:2.5.1.15] xref: EC:2.5.1.15 xref: GO:0004156 xref: MetaCyc:H2PTEROATESYNTH-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000628 name: dihydropyrimidinase activity namespace: molecular_function def: "Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate." [EC:3.5.2.2] subset: gosubset_prok synonym: "5,6-dihydropyrimidine amidohydrolase activity" EXACT [EC:3.5.2.2] synonym: "D-hydantoinase activity" EXACT [EC:3.5.2.2] synonym: "hydantoin peptidase activity" EXACT [EC:3.5.2.2] synonym: "hydantoinase activity" EXACT [EC:3.5.2.2] synonym: "hydropyrimidine hydrase activity" EXACT [EC:3.5.2.2] synonym: "pyrimidine hydrase activity" EXACT [EC:3.5.2.2] xref: EC:3.5.2.2 xref: GO:0004157 xref: MetaCyc:DIHYDROPYRIMIDINASE-RXN xref: Reactome:8430 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0000629 name: dihydroorotate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-dihydroorotate + O2 = orotate + H2O2." [EC:1.3.3.1] subset: gosubset_prok synonym: "(S)-dihydroorotate:oxygen oxidoreductase activity" EXACT [EC:1.3.3.1] synonym: "4,5-L-dihydroorotate:oxygen oxidoreductase activity" EXACT [EC:1.3.3.1] xref: EC:1.3.3.1 xref: GO:0004158 xref: MetaCyc:DIHYDROOROTOX-RXN is_a: CCO:F0000623 ! dihydroorotate dehydrogenase activity is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0000630 name: dihydrouracil dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: 5,6-dihydrouracil + NAD+ = uracil + NADH + H+." [EC:1.3.1.1] synonym: "5,6-dihydrouracil:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.1] synonym: "dehydrogenase, dihydrouracil" EXACT [EC:1.3.1.1] synonym: "pyrimidine reductase activity" EXACT [EC:1.3.1.1] synonym: "thymine reductase activity" EXACT [EC:1.3.1.1] synonym: "uracil reductase activity" EXACT [EC:1.3.1.1] xref: EC:1.3.1.1 xref: GO:0004159 xref: MetaCyc:DIHYDROURACIL-DEHYDROGENASE-(NAD+)-RXN xref: Reactome:8435 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000631 name: dihydroxy-acid dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O." [EC:4.2.1.9] subset: gosubset_prok synonym: "2,3-dihydroxy-acid hydro-lyase (3-methyl-2-oxobutanoate-forming)" EXACT [EC:4.2.1.9] synonym: "2,3-dihydroxy-acid hydro-lyase activity" EXACT [EC:4.2.1.9] synonym: "2,3-dihydroxyisovalerate dehydratase activity" EXACT [EC:4.2.1.9] synonym: "acetohydroxyacid dehydratase activity" EXACT [EC:4.2.1.9] synonym: "alpha,beta-dihydroxyacid dehydratase activity" EXACT [EC:4.2.1.9] synonym: "alpha,beta-dihydroxyisovalerate dehydratase activity" EXACT [EC:4.2.1.9] synonym: "DHAD" RELATED [EC:4.2.1.9] synonym: "dihydroxy acid dehydrase activity" EXACT [EC:4.2.1.9] xref: EC:4.2.1.9 xref: GO:0004160 xref: MetaCyc:DIHYDROXYISOVALDEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000632 name: dimethylallyltranstransferase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate." [EC:2.5.1.1] comment: Note that this is the first step in the formation of farnesyl diphosphate. The second step is 'geranyltranstransferase activity ; GO:0004337'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'. subset: gosubset_prok synonym: "(2E,6E)-farnesyl diphosphate synthetase activity" EXACT [EC:2.5.1.1] synonym: "dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity" EXACT [EC:2.5.1.1] synonym: "dimethylallyltransferase activity" EXACT [] synonym: "diprenyltransferase activity" EXACT [EC:2.5.1.1] synonym: "DMAPP:IPP-dimethylallyltransferase activity" EXACT [EC:2.5.1.1] synonym: "geranyl pyrophosphate synthase activity" EXACT [EC:2.5.1.1] synonym: "geranyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.1] synonym: "geranyl-diphosphate synthase activity" RELATED [EC:2.5.1.1] synonym: "trans-farnesyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.1] xref: EC:2.5.1.1 xref: GO:0004161 xref: MetaCyc:GPPSYN-RXN is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0000633 name: dimethylnitrosamine demethylase activity namespace: molecular_function def: "Catalysis of the removal of a methyl group from N-nitrosodimethylamine." [GOC:mah] synonym: "N-nitrosodimethylamine demethylase activity" EXACT [] xref: GO:0004162 is_a: CCO:F0004997 ! demethylase activity [Term] id: CCO:F0000634 name: diphosphomevalonate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2." [EC:4.1.1.33] subset: gosubset_prok synonym: "5-pyrophosphomevalonate decarboxylase activity" EXACT [EC:4.1.1.33] synonym: "ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)" EXACT [EC:4.1.1.33] synonym: "ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)" EXACT [EC:4.1.1.33] synonym: "mevalonate 5-diphosphate decarboxylase activity" EXACT [EC:4.1.1.33] synonym: "mevalonate diphosphate decarboxylase activity" EXACT [EC:4.1.1.33] synonym: "mevalonate pyrophosphate decarboxylase activity" EXACT [EC:4.1.1.33] synonym: "mevalonate-5-pyrophosphate decarboxylase activity" EXACT [EC:4.1.1.33] synonym: "pyrophosphomevalonate decarboxylase activity" EXACT [EC:4.1.1.33] synonym: "pyrophosphomevalonic acid decarboxylase activity" EXACT [EC:4.1.1.33] xref: EC:4.1.1.33 xref: GO:0004163 xref: MetaCyc:DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN xref: Reactome:8449 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000635 name: diphthine synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine." [EC:2.1.1.98] subset: gosubset_prok synonym: "diphthine methyltransferase activity" EXACT [EC:2.1.1.98] synonym: "S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity" EXACT [EC:2.1.1.98] synonym: "S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity" EXACT [EC:2.1.1.98] xref: EC:2.1.1.98 xref: GO:0004164 xref: MetaCyc:DIPHTHINE-SYNTHASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0000636 name: dodecenoyl-CoA delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA." [EC:5.3.3.8] subset: gosubset_prok synonym: "3,2-trans-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] synonym: "acetylene-allene isomerase activity" EXACT [EC:5.3.3.8] synonym: "delta(3),Delta(2)-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] synonym: "delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] synonym: "delta3,Delta2-enoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] synonym: "delta3-cis-delta2-trans-enoyl-CoA isomerase" BROAD [EC:5.3.3.8] synonym: "dodecenoyl-CoA (3Z)-(2E)-isomerase activity" EXACT [EC:5.3.3.8] synonym: "dodecenoyl-CoA D-isomerase activity" EXACT [] synonym: "dodecenoyl-CoA Delta-isomerase activity" EXACT [EC:5.3.3.8] synonym: "dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity" EXACT [EC:5.3.3.8] synonym: "dodecenoyl-CoA isomerase activity" EXACT [EC:5.3.3.8] xref: EC:5.3.3.8 xref: GO:0004165 xref: GO:0008461 xref: MetaCyc:ENOYL-COA-DELTA-ISOM-RXN xref: Reactome:8459 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0000637 name: dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate." [EC:2.4.1.153] synonym: "dolichyl phosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] synonym: "dolichyl phosphate N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] synonym: "dolichyl-phosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] synonym: "dolichyl-phosphate N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] synonym: "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.153] synonym: "UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] synonym: "uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.153] xref: EC:2.4.1.153 xref: GO:0004101 xref: GO:0004166 xref: MetaCyc:2.4.1.153-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0000638 name: dopachrome isomerase activity namespace: molecular_function def: "Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate." [EC:5.3.3.12] synonym: "DCF activity" EXACT [EC:5.3.3.12] synonym: "DCT activity" EXACT [EC:5.3.3.12] synonym: "dopachrome conversion activity" BROAD [] synonym: "dopachrome conversion factor activity" BROAD [EC:5.3.3.12] synonym: "dopachrome Delta(7),Delta(2)-isomerase activity" EXACT [EC:5.3.3.12] synonym: "dopachrome delta-isomerase activity" EXACT [] synonym: "dopachrome delta7,Delta2-isomerase activity" EXACT [EC:5.3.3.12] synonym: "dopachrome keto-enol isomerase activity" EXACT [EC:5.3.3.12] synonym: "dopachrome oxidoreductase activity" EXACT [EC:5.3.3.12] synonym: "dopachrome rearranging enzyme activity" EXACT [EC:5.3.3.12] synonym: "dopachrome tautomerase activity" EXACT [EC:5.3.3.12] synonym: "dopachrome-rearranging enzyme" RELATED [EC:5.3.3.12] synonym: "L-dopachrome isomerase activity" EXACT [EC:5.3.3.12] synonym: "L-dopachrome keto-enol isomerase activity" EXACT [EC:5.3.3.12] synonym: "L-dopachrome-methyl ester tautomerase activity" EXACT [EC:5.3.3.12] synonym: "TRP activity" EXACT [EC:5.3.3.12] synonym: "TRP-1" RELATED [EC:5.3.3.12] synonym: "TRP-2" RELATED [EC:5.3.3.12] synonym: "TRP2" RELATED [EC:5.3.3.12] synonym: "tryosinase-related protein-2" RELATED [EC:5.3.3.12] synonym: "tyrosinase-related protein 2 activity" EXACT [EC:5.3.3.12] xref: EC:5.3.3.12 xref: GO:0004167 xref: GO:0048059 xref: MetaCyc:DOPACHROME-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0000639 name: dolichol kinase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate." [EC:2.7.1.108] synonym: "CTP:dolichol O-phosphotransferase activity" EXACT [EC:2.7.1.108] synonym: "dolichol phosphokinase activity" EXACT [EC:2.7.1.108] xref: EC:2.7.1.108 xref: GO:0004168 xref: MetaCyc:DOLICHOL-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000640 name: dolichyl-phosphate-mannose-protein mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein." [EC:2.4.1.109] subset: gosubset_prok synonym: "dolichol phosphomannose-protein mannosyltransferase activity" EXACT [EC:2.4.1.109] synonym: "dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity" EXACT [EC:2.4.1.109] synonym: "dolichyl-phosphate-mannose-protein O-mannosyltransferase activity" EXACT [] synonym: "O-glycoside mannosyltransferase" BROAD [] synonym: "protein O-D-mannosyltransferase activity" EXACT [EC:2.4.1.109] synonym: "protein O-mannosyltransferase activity" EXACT [] xref: EC:2.4.1.109 xref: GO:0004169 xref: MetaCyc:2.4.1.109-RXN is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000641 name: dUTP diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate." [EC:3.6.1.23] subset: gosubset_prok synonym: "deoxyuridine-triphosphatase activity" EXACT [EC:3.6.1.23] synonym: "desoxyuridine 5'-triphosphatase activity" EXACT [EC:3.6.1.23] synonym: "desoxyuridine 5'-triphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.23] synonym: "dUTP nucleotidohydrolase activity" EXACT [EC:3.6.1.23] synonym: "dUTP pyrophosphatase activity" EXACT [] synonym: "dUTPase activity" EXACT [EC:3.6.1.23] xref: EC:3.6.1.23 xref: GO:0004170 xref: MetaCyc:DUTP-PYROP-RXN xref: Reactome:8479 is_a: CCO:F0006737 ! nucleoside-triphosphate diphosphatase activity [Term] id: CCO:F0000642 name: ecdysone O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + ecdysone = CoA + ecdysone palmitate." [EC:2.3.1.139] synonym: "acyl-CoA:ecdysone acyltransferase activity" EXACT [EC:2.3.1.139] synonym: "fatty acyl-CoA:ecdysone acyltransferase activity" EXACT [EC:2.3.1.139] synonym: "palmitoyl-CoA:ecdysone palmitoyltransferase activity" EXACT [EC:2.3.1.139] xref: EC:2.3.1.139 xref: GO:0004173 xref: MetaCyc:ECDYSONE-O-ACYLTRANSFERASE-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0000643 name: electron-transferring-flavoprotein dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: reduced ETF + ubiquinone = ETF + ubiquinol." [EC:1.5.5.1] subset: gosubset_prok synonym: "electron transfer flavoprotein dehydrogenase activity" EXACT [EC:1.5.5.1] synonym: "electron transfer flavoprotein Q oxidoreductase activity" EXACT [EC:1.5.5.1] synonym: "electron transfer flavoprotein reductase activity" EXACT [EC:1.5.5.1] synonym: "electron transfer flavoprotein-ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] synonym: "electron-transferring-flavoprotein:ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] synonym: "ETF dehydrogenase activity" EXACT [EC:1.5.5.1] synonym: "ETF-QO activity" EXACT [EC:1.5.5.1] synonym: "ETF-ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] synonym: "ETF:ubiquinone oxidoreductase activity" EXACT [EC:1.5.5.1] xref: EC:1.5.5.1 xref: GO:0004174 xref: MetaCyc:1.5.5.1-RXN xref: Reactome:8494 is_a: CCO:F0003248 ! oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor [Term] id: CCO:F0000644 name: endopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides, and comprising any enzyme of sub-subclasses EC:3.4.21-99. They are classfied according to the presence of essential catalytic residues or ions at their active sites." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "endoprotease activity" EXACT [] synonym: "proteasome endopeptidase activity" NARROW [] synonym: "proteasome endopeptidase regulator" RELATED [] synonym: "proteinase" BROAD [] xref: GO:0004175 xref: GO:0016809 xref: Reactome:1793 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0000645 name: ATP-dependent peptidase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the hydrolysis of peptide bonds." [GOC:mah] subset: gosubset_prok xref: GO:0004176 xref: GO:0004280 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0000646 name: aminopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of N-terminal amino acid residues from oligopeptides or polypeptides." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:3.4.11 xref: GO:0004177 is_a: CCO:F0001788 ! exopeptidase activity [Term] id: CCO:F0000647 name: leucyl aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of an N-terminal amino acid, Xaa-Xbb-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Xbb may be Pro." [EC:3.4.11.1] subset: gosubset_prok synonym: "aminopeptidase II" RELATED [EC:3.4.11.1] synonym: "cathepsin III" RELATED [EC:3.4.11.1] synonym: "cytosol aminopeptidase activity" NARROW [EC:3.4.11.1] synonym: "FTBL proteins" RELATED [EC:3.4.11.1] synonym: "L-leucine aminopeptidase activity" EXACT [EC:3.4.11.1] synonym: "leucinamide aminopeptidase activity" EXACT [EC:3.4.11.1] synonym: "leucinaminopeptidase activity" EXACT [EC:3.4.11.1] synonym: "leucine aminopeptidase activity" EXACT [EC:3.4.11.1] synonym: "leucyl peptidase activity" EXACT [EC:3.4.11.1] synonym: "peptidase S activity" NARROW [EC:3.4.11.1] synonym: "proteinates FTBL" RELATED [EC:3.4.11.1] xref: EC:3.4.11.1 xref: GO:0004178 xref: MetaCyc:3.4.11.1-RXN is_a: CCO:F0000646 ! aminopeptidase activity is_a: CCO:F0001785 ! metalloexopeptidase activity [Term] id: CCO:F0000648 name: membrane alanyl aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of an N-terminal amino acid, Xaa-Xbb- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide." [EC:3.4.11.2] subset: gosubset_prok synonym: "alanine-specific aminopeptidase activity" EXACT [EC:3.4.11.2] synonym: "alanyl aminopeptidase activity" EXACT [EC:3.4.11.2] synonym: "amino-oligopeptidase activity" EXACT [EC:3.4.11.2] synonym: "aminopeptidase M activity" NARROW [EC:3.4.11.2] synonym: "aminopeptidase N activity" NARROW [EC:3.4.11.2] synonym: "CD13" RELATED [EC:3.4.11.2] synonym: "cysteinylglycinase activity" EXACT [EC:3.4.11.2] synonym: "cysteinylglycine dipeptidase activity" EXACT [EC:3.4.11.2] synonym: "L-alanine aminopeptidase activity" EXACT [EC:3.4.11.2] synonym: "membrane alanine aminopeptidase activity" NARROW [EC:3.4.11.2] synonym: "membrane aminopeptidase I activity" NARROW [EC:3.4.11.2] synonym: "microsomal aminopeptidase activity" NARROW [EC:3.4.11.2] synonym: "particle-bound aminopeptidase activity" NARROW [EC:3.4.11.2] synonym: "peptidase E activity" BROAD [EC:3.4.11.2] synonym: "pseudo leucine aminopeptidase activity" EXACT [EC:3.4.11.2] xref: EC:3.4.11.2 xref: GO:0004179 xref: MetaCyc:3.4.11.2-RXN is_a: CCO:F0001785 ! metalloexopeptidase activity is_a: CCO:F0003101 ! alanine aminopeptidase activity [Term] id: CCO:F0000649 name: carboxypeptidase activity namespace: molecular_function def: "Catalysis of the hydrolytic cleavage of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0004180 is_a: CCO:F0001788 ! exopeptidase activity [Term] id: CCO:F0000650 name: metallocarboxypeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of C-terminal amino acid residues from oligopeptides or polypeptides; a bivalent cation is an essential component of the catalytic mechanism." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:3.4.17 xref: GO:0004181 is_a: CCO:F0000649 ! carboxypeptidase activity is_a: CCO:F0001785 ! metalloexopeptidase activity [Term] id: CCO:F0000651 name: carboxypeptidase A activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid. Little or no action with -Asp, -Glu, -Arg, -Lys or -Pro." [EC:3.4.17.1] subset: gosubset_prok synonym: "carboxypolypeptidase activity" EXACT [EC:3.4.17.1] synonym: "pancreatic carboxypeptidase A" RELATED [EC:3.4.17.1] synonym: "tissue carboxypeptidase A" RELATED [EC:3.4.17.1] xref: EC:3.4.17.1 xref: GO:0004182 xref: GO:0008731 xref: MetaCyc:CARBOXYPEPTIDASE-A-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0000652 name: carboxypeptidase E activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents." [EC:3.4.17.10] synonym: "carboxypeptidase H activity" EXACT [] synonym: "cobalt-stimulated chromaffin granule carboxypeptidase activity" EXACT [EC:3.4.17.10] synonym: "enkephalin convertase activity" NARROW [EC:3.4.17.10] synonym: "enkephalin precursor carboxypeptidase activity" EXACT [EC:3.4.17.10] synonym: "enkephalin-precursor endopeptidase activity" EXACT [EC:3.4.17.10] synonym: "insulin granule-associated carboxypeptidase activity" EXACT [EC:3.4.17.10] synonym: "membrane-bound carboxypeptidase activity" EXACT [EC:3.4.17.10] synonym: "peptidyl-L-lysine(-L-arginine) hydrolase" BROAD [EC:3.4.17.10] xref: EC:3.4.17.10 xref: GO:0004183 xref: MetaCyc:CARBOXYPEPTIDASE-H-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0000653 name: lysine carboxypeptidase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma." [EC:3.4.17.3] synonym: "anaphylatoxin inactivator activity" NARROW [EC:3.4.17.3] synonym: "arginine carboxypeptidase activity" EXACT [EC:3.4.17.3] synonym: "bradykinase activity" EXACT [EC:3.4.17.3] synonym: "bradykinin-decomposing enzyme" RELATED [EC:3.4.17.3] synonym: "carboxypeptidase N activity" EXACT [] synonym: "CPase N" RELATED [EC:3.4.17.3] synonym: "creatine kinase conversion factor" RELATED [EC:3.4.17.3] synonym: "creatinine kinase convertase activity" EXACT [EC:3.4.17.3] synonym: "hippuryllysine hydrolase activity" EXACT [EC:3.4.17.3] synonym: "kininase I activity" EXACT [EC:3.4.17.3] synonym: "kininase Ia" RELATED [EC:3.4.17.3] synonym: "lysine (arginine) carboxypeptidase activity" EXACT [] synonym: "lysine(arginine) carboxypeptidase activity" EXACT [EC:3.4.17.3] synonym: "peptidyl-L-lysine(-L-arginine) hydrolase" BROAD [EC:3.4.17.3] synonym: "plasma carboxypeptidase B" RELATED [EC:3.4.17.3] xref: EC:3.4.17.3 xref: GO:0004184 xref: MetaCyc:LYSINE(ARGININE)-CARBOXYPEPTIDASE-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0000654 name: serine carboxypeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of carboxyl terminal peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [EC:3.4.16.-, http://en.wikipedia.org/wiki/Serine_hydrolase] subset: gosubset_prok xref: EC:3.4.16 xref: GO:0004185 xref: Reactome:8533 is_a: CCO:F0000649 ! carboxypeptidase activity is_a: CCO:F0001786 ! serine-type peptidase activity [Term] id: CCO:F0000655 name: carboxypeptidase C activity namespace: molecular_function def: "Catalysis of the release of a C-terminal amino acid with a broad specificity." [EC:3.4.16.5] synonym: "carboxypeptidase Y activity" EXACT [EC:3.4.16.5] synonym: "cathepsin A activity" NARROW [EC:3.4.16.5] synonym: "deamidase" RELATED [EC:3.4.16.5] synonym: "lysosomal carboxypeptidase A" NARROW [EC:3.4.16.5] synonym: "lysosomal protective protein activity" NARROW [EC:3.4.16.5] synonym: "serine carboxypeptidase I activity" EXACT [EC:3.4.16.5] synonym: "serine-type carboxypeptidase I activity" EXACT [EC:3.4.16.5] synonym: "vacuolar carboxypeptidase Y" NARROW [] xref: EC:3.4.16.5 xref: GO:0004186 xref: MetaCyc:3.4.16.5-RXN is_a: CCO:F0000654 ! serine carboxypeptidase activity [Term] id: CCO:F0000656 name: carboxypeptidase D activity namespace: molecular_function def: "Catalysis of the preferential release of a C-terminal arginine or lysine residue. Function is inhibited by diisopropyl fluorophosphate and sensitive to thiol-blocking reagents." [EC:3.4.16.6] synonym: "carboxypeptidase Kex1" RELATED [EC:3.4.16.6] synonym: "carboxypeptidase KEX1 activity" NARROW [EC:3.4.16.6] synonym: "carboxypeptidase S1 activity" EXACT [EC:3.4.16.6] synonym: "cereal serine carboxypeptidase II" RELATED [EC:3.4.16.6] synonym: "CPDW-II" RELATED [EC:3.4.16.6] synonym: "gene KEX1 serine carboxypeptidase" NARROW [EC:3.4.16.6] synonym: "KEX1 carboxypeptidase activity" EXACT [EC:3.4.16.6] synonym: "KEX1 proteinase activity" EXACT [EC:3.4.16.6] synonym: "KEX1DELTAp" RELATED [EC:3.4.16.6] synonym: "saccharomyces cerevisiae KEX1 gene product" RELATED [EC:3.4.16.6] xref: EC:3.4.16.6 xref: GO:0004187 xref: MetaCyc:3.4.16.6-RXN is_a: CCO:F0000654 ! serine carboxypeptidase activity [Term] id: CCO:F0000657 name: serine-type Pro-X carboxypeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a Pro-Xaa bond by a serine-type peptidase mechanism to release a C-terminal amino acid." [EC:3.4.16.2] synonym: "aminoacylproline carboxypeptidase activity" EXACT [EC:3.4.16.2] synonym: "angiotensinase C activity" NARROW [EC:3.4.16.2] synonym: "lysosomal carboxypeptidase C activity" NARROW [EC:3.4.16.2] synonym: "lysosomal Pro-X carboxypeptidase activity" NARROW [] synonym: "lysosomal Pro-Xaa carboxypeptidase activity" EXACT [EC:3.4.16.2] synonym: "PCP" RELATED [EC:3.4.16.2] synonym: "peptidylprolylamino acid carboxypeptidase activity" EXACT [EC:3.4.16.2] synonym: "proline carboxypeptidase activity" EXACT [EC:3.4.16.2] synonym: "proline-specific carboxypeptidase P" RELATED [EC:3.4.16.2] synonym: "prolyl carboxypeptidase activity" EXACT [EC:3.4.16.2] xref: EC:3.4.16.2 xref: GO:0004188 xref: GO:0008323 xref: MetaCyc:3.4.16.2-RXN is_a: CCO:F0000654 ! serine carboxypeptidase activity is_a: CCO:F0001834 ! Pro-X carboxypeptidase activity [Term] id: CCO:F0000658 name: tubulinyl-Tyr carboxypeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of the Glu-Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr." [EC:3.4.17.17] synonym: "brain I carboxypeptidase activity" EXACT [EC:3.4.17.17] synonym: "carboxypeptidase-tubulin activity" EXACT [EC:3.4.17.17] synonym: "soluble carboxypeptidase activity" RELATED [EC:3.4.17.17] synonym: "TTCPase activity" EXACT [EC:3.4.17.17] synonym: "tubulin carboxypeptidase activity" EXACT [EC:3.4.17.17] synonym: "tubulin-tyrosine carboxypeptidase activity" EXACT [EC:3.4.17.17] synonym: "tubulinyl-tyrosine carboxypeptidase activity" EXACT [] synonym: "tubulinyltyrosine carboxypeptidase activity" EXACT [EC:3.4.17.17] synonym: "tyrosinotubulin carboxypeptidase activity" EXACT [EC:3.4.17.17] synonym: "tyrosyltubulin carboxypeptidase activity" EXACT [EC:3.4.17.17] xref: EC:3.4.17.17 xref: GO:0004189 xref: MetaCyc:3.4.17.17-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0000659 name: aspartic-type endopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "aspartic endopeptidase activity" EXACT [] synonym: "aspartic protease activity" EXACT [] synonym: "aspartyl protease activity" EXACT [] synonym: "carboxyl protease activity" EXACT [] xref: EC:3.4.23 xref: GO:0004190 xref: Reactome:1933 is_a: CCO:F0000644 ! endopeptidase activity [Term] id: CCO:F0000660 name: barrierpepsin activity namespace: molecular_function def: "Catalysis of the selected cleavage of the Leu6-Lys7 bond in the pheromone alpha-mating factor." [EC:3.4.23.35] synonym: "Bar proteinase activity" NARROW [EC:3.4.23.35] synonym: "barrier proteinase activity" EXACT [EC:3.4.23.35] synonym: "extracellular 'barrier' protein activity" RELATED [EC:3.4.23.35] xref: EC:3.4.23.35 xref: GO:0004191 xref: MetaCyc:3.4.23.35-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0000661 name: cathepsin D activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin." [EC:3.4.23.5] xref: EC:3.4.23.5 xref: GO:0004192 xref: MetaCyc:3.4.23.5-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0000662 name: cathepsin E activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity." [EC:3.4.23.34] synonym: "cathepsin D-like acid proteinase activity" EXACT [EC:3.4.23.34] synonym: "cathepsin D-type proteinase activity" EXACT [EC:3.4.23.34] synonym: "cathepsin E-like acid proteinase activity" EXACT [EC:3.4.23.34] synonym: "EMAP" RELATED [EC:3.4.23.34] synonym: "erythrocyte membrane aspartic proteinase activity" NARROW [EC:3.4.23.34] synonym: "non-pepsin proteinase activity" EXACT [EC:3.4.23.34] synonym: "slow-moving proteinase activity" RELATED [EC:3.4.23.34] synonym: "SMP" RELATED [EC:3.4.23.34] xref: EC:3.4.23.34 xref: GO:0004193 xref: MetaCyc:3.4.23.34-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0000663 name: pepsin A activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin." [EC:3.4.23.1] synonym: "elixir lactate of pepsin" RELATED [EC:3.4.23.1] synonym: "fundus-pepsin" RELATED [EC:3.4.23.1] synonym: "lactated pepsin" RELATED [EC:3.4.23.1] synonym: "lactated pepsin elixir" RELATED [EC:3.4.23.1] synonym: "P I" RELATED [EC:3.4.23.1] synonym: "P II" RELATED [EC:3.4.23.1] synonym: "pepsin activity" BROAD [EC:3.4.23.1] synonym: "pepsin D" RELATED [EC:3.4.23.1] synonym: "pepsin fortior" RELATED [EC:3.4.23.1] synonym: "pepsin R" RELATED [EC:3.4.23.1] xref: EC:3.4.23.1 xref: GO:0004194 xref: MetaCyc:3.4.23.1-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0000664 name: renin activity namespace: molecular_function def: "Catalysis of the cleavage of Leu-Xaa bond in angiotensinogen to generate angiotensin I." [EC:3.4.23.15] synonym: "angiotensin-forming enzyme activity" EXACT [EC:3.4.23.15] synonym: "angiotensinogenase activity" EXACT [EC:3.4.23.15] xref: EC:3.4.23.15 xref: GO:0004195 xref: MetaCyc:3.4.23.15-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0000665 name: saccharopepsin activity namespace: molecular_function def: "Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24." [EC:3.4.23.25] synonym: "aspartic proteinase yscA" RELATED [EC:3.4.23.25] synonym: "PRA" RELATED [EC:3.4.23.25] synonym: "proteinase A" RELATED [EC:3.4.23.25] synonym: "proteinase yscA" RELATED [EC:3.4.23.25] synonym: "saccharomyces aspartic proteinase activity" EXACT [EC:3.4.23.25] synonym: "Saccharomyces aspartic proteinase activity" NARROW [EC:3.4.23.25] synonym: "saccharomyces cerevisiae aspartic proteinase A" RELATED [EC:3.4.23.25] synonym: "yeast endopeptidase A activity" NARROW [EC:3.4.23.25] synonym: "yeast proteinase A" RELATED [EC:3.4.23.25] xref: EC:3.4.23.25 xref: GO:0004196 xref: MetaCyc:3.4.23.25-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0000666 name: cysteine-type endopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center." [EC:3.4.22.-, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "lysosomal cysteine-type endopeptidase" NARROW [] synonym: "thiol endopeptidase activity" EXACT [] xref: EC:3.4.22 xref: GO:0004197 is_a: CCO:F0000644 ! endopeptidase activity is_a: CCO:F0001784 ! cysteine-type peptidase activity [Term] id: CCO:F0000667 name: calcium-dependent cysteine-type endopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium." [GOC:mah] subset: gosubset_prok synonym: "calpain activity" NARROW [] xref: GO:0004198 is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0000668 name: cathepsin B activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides." [EC:3.4.22.1] synonym: "cathepsin B1 activity" EXACT [EC:3.4.22.1] synonym: "cathepsin II" RELATED [EC:3.4.22.1] xref: EC:3.4.22.1 xref: GO:0004213 xref: MetaCyc:3.4.22.1-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0000669 name: dipeptidyl-peptidase I activity namespace: molecular_function def: "Catalysis of the release of an N-terminal dipeptide, Xaa-Xbb from Xaa-Xbb-Xcc, except when Xaa is Arg or Lys, or Xbb or Xcc is Pro." [EC:3.4.14.1] synonym: "cathepsin C activity" EXACT [EC:3.4.14.1] synonym: "cathepsin J activity" EXACT [EC:3.4.14.1] synonym: "DAP I" RELATED [EC:3.4.14.1] synonym: "dipeptide arylamidase I" RELATED [EC:3.4.14.1] synonym: "dipeptidyl aminopeptidase I activity" EXACT [EC:3.4.14.1] synonym: "dipeptidyl transferase activity" EXACT [EC:3.4.14.1] xref: EC:3.4.14.1 xref: GO:0004214 xref: MetaCyc:3.4.14.1-RXN is_a: CCO:F0001784 ! cysteine-type peptidase activity is_a: CCO:F0001789 ! dipeptidyl-peptidase activity [Term] id: CCO:F0000670 name: cathepsin H activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds, acting as an aminopeptidase (notably, cleaving Arg-Xaa bonds) as well as an endopeptidase." [EC:3.4.22.16] synonym: "aleurain activity" EXACT [EC:3.4.22.16] synonym: "benzoylarginine-naphthylamide (BANA) hydrolase activity" EXACT [EC:3.4.22.16] synonym: "cathepsin B3 activity" EXACT [EC:3.4.22.16] synonym: "cathepsin Ba" RELATED [EC:3.4.22.16] synonym: "cathepsin BA activity" EXACT [EC:3.4.22.16] synonym: "N-benzoylarginine-beta-naphthylamide hydrolase activity" EXACT [EC:3.4.22.16] xref: EC:3.4.22.16 xref: GO:0004215 xref: MetaCyc:3.4.22.16-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0000671 name: cathepsin K activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Has a broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg." [EC:3.4.22.38] synonym: "cathepsin O activity" EXACT [EC:3.4.22.38] synonym: "cathepsin O2 activity" EXACT [EC:3.4.22.38] synonym: "cathepsin X activity" EXACT [EC:3.4.22.38] xref: EC:3.4.22.38 xref: GO:0004216 xref: MetaCyc:3.4.22.38-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0000672 name: cathepsin L activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity." [EC:3.4.22.15] synonym: "Aldrichina grahami cysteine proteinase" NARROW [EC:3.4.22.15] xref: EC:3.4.22.15 xref: GO:0004217 xref: MetaCyc:3.4.22.15-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0000673 name: cathepsin S activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin L, but with much less activity on the terminal bond of Z-Phe-Arg-NHMec, and more activity on the terminal bond of Z-Val-Val-Arg-Xaa compounds." [EC:3.4.22.27] xref: EC:3.4.22.27 xref: GO:0004218 xref: MetaCyc:3.4.22.27-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0000674 name: pyroglutamyl-peptidase I activity namespace: molecular_function def: "Catalysis of the reaction: pyroglutamyl-peptide + H2O = pyroglutamate + peptide." [EC:3.4.19.3] comment: Note that pyroglutamic acid has sometimes been referred to as 5-oxoproline. subset: gosubset_prok synonym: "5-oxoprolyl-peptidase activity" EXACT [EC:3.4.19.3] synonym: "L-pyroglutamyl peptide hydrolase activity" EXACT [EC:3.4.19.3] synonym: "L-pyrrolidonecarboxylate peptidase activity" EXACT [EC:3.4.19.3] synonym: "pyrase activity" EXACT [EC:3.4.19.3] synonym: "PYRase activity" EXACT [EC:3.4.19.3] synonym: "pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.3] synonym: "pyroglutamidase activity" EXACT [EC:3.4.19.3] synonym: "pyroglutamyl aminopeptidase activity" EXACT [EC:3.4.19.3] synonym: "pyrrolidone carboxyl peptidase activity" EXACT [EC:3.4.19.3] synonym: "pyrrolidone-carboxyl peptidase activity" EXACT [EC:3.4.19.3] synonym: "pyrrolidone-carboxylate peptidase activity" EXACT [EC:3.4.19.3] synonym: "pyrrolidonecarboxylyl peptidase activity" EXACT [EC:3.4.19.3] synonym: "pyrrolidonyl peptidase activity" EXACT [EC:3.4.19.3] xref: EC:3.4.19.3 xref: GO:0004219 xref: MetaCyc:PYROGLUTAMYL-PEPTIDASE-I-RXN is_a: CCO:F0001784 ! cysteine-type peptidase activity is_a: CCO:F0003470 ! pyroglutamyl-peptidase activity [Term] id: CCO:F0000675 name: ubiquitin thiolesterase activity namespace: molecular_function def: "Catalysis of the reaction: ubiquitin C-terminal thiolester + H2O = ubiquitin + a thiol. Hydrolysis of esters, including those formed between thiols such as dithiothreitol or glutathione and the C-terminal glycine residue of the polypeptide ubiquitin, and AMP-ubiquitin." [EC:3.1.2.15] comment: Note that this term is distinguished from its parent in that it specifically refers to hydrolysis of thiolester bonds. subset: gosubset_prok synonym: "isopeptidase activity" EXACT [EC:3.1.2.15] synonym: "isopeptidase T" RELATED [EC:3.1.2.15] synonym: "ubiquitin C-terminal hydrolase activity" EXACT [] synonym: "ubiquitin carboxy-terminal esterase activity" EXACT [EC:3.1.2.15] synonym: "ubiquitin carboxy-terminal hydrolase activity" EXACT [EC:3.1.2.15] synonym: "ubiquitin thioesterase activity" EXACT [EC:3.1.2.15] synonym: "ubiquitin-C-terminal-thioester hydrolase activity" EXACT [EC:3.1.2.15] synonym: "ubiquitinyl hydrolase 1 activity" NARROW [] xref: EC:3.1.2.15 xref: GO:0004221 xref: GO:0008577 xref: MetaCyc:UBIQUITIN-THIOLESTERASE-RXN is_a: CCO:F0001199 ! ubiquitin-specific protease activity is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0000676 name: metalloendopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides. Enzymes of this class contain a chelated metal ion essential to their catalytic activity at their active sites." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "metalloprotease" BROAD [] synonym: "metalloproteinase" BROAD [] xref: EC:3.4.24 xref: GO:0004222 xref: Reactome:1791 is_a: CCO:F0000644 ! endopeptidase activity is_a: CCO:F0001787 ! metallopeptidase activity [Term] id: CCO:F0000677 name: Gly-X carboxypeptidase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-Gly-Xaa + H2O = peptidyl-Gly + Xaa." [EC:3.4.17.4] subset: gosubset_prok synonym: "carboxypeptidase a" RELATED [EC:3.4.17.4] synonym: "carboxypeptidase S activity" EXACT [EC:3.4.17.4] synonym: "Gly-Xaa carboxypeptidase activity" EXACT [EC:3.4.17.4] synonym: "glycine carboxypeptidase activity" EXACT [EC:3.4.17.4] synonym: "peptidase alpha" RELATED [EC:3.4.17.4] synonym: "yeast carboxypeptidase activity" EXACT [EC:3.4.17.4] xref: EC:3.4.17.4 xref: GO:0004226 xref: MetaCyc:GLY-X-CARBOXYPEPTIDASE-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0000678 name: gelatinase A activity namespace: molecular_function def: "Catalysis of the cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-Ile-Ala-Gly-Gln at the Gly-Ile bond." [EC:3.4.24.24] synonym: "3/4 collagenase activity" EXACT [EC:3.4.24.24] synonym: "72 kDa gelatinase type A" RELATED [EC:3.4.24.24] synonym: "72-kDa gelatinase activity" NARROW [EC:3.4.24.24] synonym: "collagenase IV" RELATED [EC:3.4.24.24] synonym: "collagenase type IV" RELATED [EC:3.4.24.24] synonym: "matrix metalloproteinase 2 activity" EXACT [EC:3.4.24.24] synonym: "matrix metalloproteinase 5" RELATED [EC:3.4.24.24] synonym: "MMP 2" RELATED [EC:3.4.24.24] synonym: "MMP-2" EXACT [] synonym: "type IV collagen metalloproteinase" BROAD [EC:3.4.24.24] synonym: "type IV collagenase activity" EXACT [EC:3.4.24.24] synonym: "type IV collagenase/gelatinase activity" EXACT [EC:3.4.24.24] xref: EC:3.4.24.24 xref: GO:0004228 xref: MetaCyc:3.4.24.24-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000679 name: gelatinase B activity namespace: molecular_function def: "Catalysis of the cleavage of gelatin types I and V and collagen types IV and V." [EC:3.4.24.35] synonym: "92-kDa gelatinase activity" NARROW [EC:3.4.24.35] synonym: "92-kDa type IV collagenase activity" NARROW [EC:3.4.24.35] synonym: "95 kDa type IV collagenase/gelatinase activity" EXACT [EC:3.4.24.35] synonym: "collagenase IV" RELATED [EC:3.4.24.35] synonym: "collagenase type IV" RELATED [EC:3.4.24.35] synonym: "gelatinase MMP 9" RELATED [EC:3.4.24.35] synonym: "macrophage gelatinase activity" NARROW [EC:3.4.24.35] synonym: "matrix metalloproteinase 9 activity" EXACT [EC:3.4.24.35] synonym: "MMP 9" RELATED [EC:3.4.24.35] synonym: "MMP-9" EXACT [] synonym: "type IV collagen metalloproteinase" BROAD [EC:3.4.24.35] synonym: "type V collagenase activity" EXACT [EC:3.4.24.35] xref: EC:3.4.24.35 xref: GO:0004229 xref: MetaCyc:3.4.24.35-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000680 name: glutamyl aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide." [EC:3.4.11.7] subset: gosubset_prok synonym: "aminopeptidase A" RELATED [EC:3.4.11.7] synonym: "angiotensinase A" RELATED [EC:3.4.11.7] synonym: "angiotensinase A2" RELATED [EC:3.4.11.7] synonym: "antigen BP-1/6C3 of mouse B lymphocytes" RELATED [EC:3.4.11.7] synonym: "aspartate aminopeptidase activity" EXACT [EC:3.4.11.7] synonym: "Ca2+-activated glutamate aminopeptidase activity" EXACT [EC:3.4.11.7] synonym: "glutamyl peptidase activity" EXACT [EC:3.4.11.7] synonym: "L-aspartate aminopeptidase activity" EXACT [EC:3.4.11.7] synonym: "membrane aminopeptidase II" RELATED [EC:3.4.11.7] xref: EC:3.4.11.7 xref: GO:0004230 xref: MetaCyc:3.4.11.7-RXN is_a: CCO:F0000646 ! aminopeptidase activity is_a: CCO:F0001785 ! metalloexopeptidase activity [Term] id: CCO:F0000681 name: insulysin activity namespace: molecular_function def: "Catalysis of the degradation of insulin, glucagon and other polypeptides. No action on proteins." [EC:3.4.24.56] subset: gosubset_prok synonym: "IDE" RELATED [EC:3.4.24.56] synonym: "insulin protease activity" EXACT [EC:3.4.24.56] synonym: "insulin proteinase activity" EXACT [EC:3.4.24.56] synonym: "insulin-degrading enzyme activity" EXACT [EC:3.4.24.56] synonym: "insulin-degrading neutral proteinase activity" EXACT [EC:3.4.24.56] synonym: "insulin-glucagon protease activity" EXACT [EC:3.4.24.56] synonym: "insulin-specific protease activity" EXACT [EC:3.4.24.56] synonym: "insulinase activity" EXACT [EC:3.4.24.56] synonym: "metalloinsulinase activity" EXACT [EC:3.4.24.56] xref: EC:3.4.24.56 xref: GO:0004231 xref: MetaCyc:3.4.24.56-RXN xref: Reactome:9609 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000682 name: interstitial collagenase activity namespace: molecular_function def: "Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue." [EC:3.4.24.7] synonym: "matrix metalloproteinase 1" EXACT [] synonym: "MMP-1" EXACT [] synonym: "vertebrate collagenase activity" EXACT [EC:3.4.24.7] xref: EC:3.4.24.7 xref: GO:0004232 xref: MetaCyc:3.4.24.7-RXN is_a: CCO:F0001737 ! collagenase activity [Term] id: CCO:F0000683 name: macrophage elastase activity namespace: molecular_function def: "Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin." [EC:3.4.24.65] synonym: "human macrophage metalloelastase (HME)" EXACT [EC:3.4.24.65] synonym: "matrix metalloproteinase 12 activity" EXACT [EC:3.4.24.65] synonym: "metalloelastase activity" EXACT [EC:3.4.24.65] synonym: "metalloesterase activity" EXACT [] synonym: "MMP-12" EXACT [] xref: EC:3.4.24.65 xref: GO:0004234 xref: MetaCyc:3.4.24.65-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity is_a: CCO:F0005704 ! elastase activity [Term] id: CCO:F0000684 name: matrilysin activity namespace: molecular_function def: "Catalysis of the cleavage of Ala14-Leu15 and Tyr16-Leu17 in B chain of insulin. No action on collagen types I, II, IV and V. Cleaves gelatin chain alpha-2(I) > alpha-1(I)." [EC:3.4.24.23] synonym: "matrin activity" EXACT [EC:3.4.24.23] synonym: "matrix metalloproteinase 7 activity" EXACT [EC:3.4.24.23] synonym: "matrix metalloproteinase pump 1" RELATED [EC:3.4.24.23] synonym: "metalloproteinase pump-1" RELATED [EC:3.4.24.23] synonym: "MMP" RELATED [EC:3.4.24.23] synonym: "MMP 7" RELATED [EC:3.4.24.23] synonym: "MMP-7" EXACT [] synonym: "PUMP" RELATED [EC:3.4.24.23] synonym: "PUMP-1 activity" NARROW [EC:3.4.24.23] synonym: "PUMP-1 proteinase activity" EXACT [EC:3.4.24.23] synonym: "putative (or punctuated) metalloproteinase-1 activity" NARROW [EC:3.4.24.23] synonym: "putative metalloproteinase activity" EXACT [EC:3.4.24.23] synonym: "uterine metalloendopeptidase activity" NARROW [EC:3.4.24.23] xref: EC:3.4.24.23 xref: GO:0004235 xref: MetaCyc:3.4.24.23-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000685 name: membrane dipeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of dipeptides." [EC:3.4.13.19] subset: gosubset_prok synonym: "aminodipeptidase activity" EXACT [EC:3.4.13.19] synonym: "dehydropeptidase I (DPH I)" RELATED [EC:3.4.13.19] synonym: "dehydropeptidase I activity" EXACT [EC:3.4.13.19] synonym: "dipeptide hydrolase" BROAD [EC:3.4.13.19] synonym: "dipeptidyl hydrolase activity" EXACT [EC:3.4.13.19] synonym: "DPH I activity" NARROW [EC:3.4.13.19] synonym: "glycosyl-phosphatidylinositol-anchored renal dipeptidase activity" EXACT [EC:3.4.13.19] synonym: "MDP" RELATED [EC:3.4.13.19] synonym: "microsomal dipeptidase activity" NARROW [EC:3.4.13.19] synonym: "nonspecific dipeptidase activity" EXACT [EC:3.4.13.19] synonym: "renal dipeptidase activity" NARROW [EC:3.4.13.19] xref: EC:3.4.13.19 xref: GO:0004237 xref: MetaCyc:3.4.13.19-RXN is_a: CCO:F0001785 ! metalloexopeptidase activity is_a: CCO:F0003375 ! dipeptidase activity [Term] id: CCO:F0000686 name: meprin A activity namespace: molecular_function def: "Catalysis of the hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues." [EC:3.4.24.18] synonym: "endopeptidase-2 activity" BROAD [EC:3.4.24.18] synonym: "meprin" RELATED [EC:3.4.24.18] synonym: "meprin-a" RELATED [EC:3.4.24.18] synonym: "N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase activity" EXACT [EC:3.4.24.18] synonym: "PABA-peptide hydrolase activity" EXACT [EC:3.4.24.18] synonym: "PPH" RELATED [EC:3.4.24.18] xref: EC:3.4.24.18 xref: GO:0004238 xref: MetaCyc:3.4.24.18-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000687 name: methionyl aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of N-terminal amino acids, preferentially methionine, from peptides and arylamides." [EC:3.4.11.18] subset: gosubset_prok synonym: "L-methionine aminopeptidase activity" EXACT [EC:3.4.11.18] synonym: "MAP" RELATED [EC:3.4.11.18] synonym: "methionine aminopeptidase activity" EXACT [EC:3.4.11.18] synonym: "peptidase M activity" EXACT [EC:3.4.11.18] xref: EC:3.4.11.18 xref: GO:0004239 xref: MetaCyc:3.4.11.18-RXN is_a: CCO:F0000646 ! aminopeptidase activity is_a: CCO:F0001785 ! metalloexopeptidase activity [Term] id: CCO:F0000688 name: mitochondrial processing peptidase activity namespace: molecular_function def: "Catalysis of the release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2." [EC:3.4.24.64] synonym: "alpha-mitochondrial processing peptidase" NARROW [] synonym: "beta-mitochondrial processing peptidase" NARROW [] synonym: "matrix peptidase" RELATED [EC:3.4.24.64] synonym: "matrix processing peptidase" RELATED [EC:3.4.24.64] synonym: "matrix processing proteinase" RELATED [EC:3.4.24.64] synonym: "mitochondrial protein precursor-processing proteinase activity" EXACT [EC:3.4.24.64] synonym: "MPP" EXACT [] synonym: "processing enhancing peptidase (for one of two subunits)" RELATED [EC:3.4.24.64] synonym: "processing enhancing peptidase activity" NARROW [EC:3.4.24.64] xref: EC:3.4.24.64 xref: GO:0004240 xref: MetaCyc:3.4.24.64-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity is_a: CCO:F0002335 ! signal peptidase activity [Term] id: CCO:F0000689 name: mitochondrial intermediate peptidase activity namespace: molecular_function def: "Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion." [EC:3.4.24.59] synonym: "MIP" BROAD [] synonym: "mitochondrial intermediate precursor-processing proteinase activity" EXACT [EC:3.4.24.59] xref: EC:3.4.24.59 xref: GO:0004243 xref: MetaCyc:3.4.24.59-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000690 name: mitochondrial inner membrane peptidase activity namespace: molecular_function def: "Catalysis of the maturation of mitochondrial precursor proteins delivered to the intermembrane space." [PMID:12191769] synonym: "IMP" BROAD [] xref: EC:3.4.99.- xref: GO:0004244 is_a: CCO:F0000644 ! endopeptidase activity [Term] id: CCO:F0000691 name: neprilysin activity namespace: molecular_function def: "Catalysis of the preferential cleavage at the amino group of hydrophobic residues in insulin, casein, hemoglobin, and a number of other proteins and polypeptides." [EC:3.4.24.11] subset: gosubset_prok synonym: "acute lymphoblastic leukemia antigen" RELATED [EC:3.4.24.11] synonym: "CALLA" RELATED [EC:3.4.24.11] synonym: "CALLA (common acute lymphoblastic leukemia-associated) antigens" RELATED [EC:3.4.24.11] synonym: "CALLA antigen" RELATED [EC:3.4.24.11] synonym: "CALLA glycoprotein" RELATED [EC:3.4.24.11] synonym: "CALLA glycoproteins" RELATED [EC:3.4.24.11] synonym: "CD10" RELATED [EC:3.4.24.11] synonym: "common acute lymphoblastic leukemia antigen" RELATED [EC:3.4.24.11] synonym: "common acute lymphoblastic leukemia-associated antigens" RELATED [EC:3.4.24.11] synonym: "endopeptidase 24.11" RELATED [EC:3.4.24.11] synonym: "endopeptidase-2 activity" BROAD [EC:3.4.24.11] synonym: "enkephalinase activity" EXACT [EC:3.4.24.11] synonym: "kidney-brush-border neutral endopeptidase" NARROW [EC:3.4.24.11] synonym: "kidney-brush-border neutral peptidase" NARROW [EC:3.4.24.11] synonym: "kidney-brush-border neutral proteinase activity" NARROW [EC:3.4.24.11] synonym: "membrane metalloendopeptidase activity" NARROW [EC:3.4.24.11] synonym: "neutral endopeptidase 24.11" RELATED [EC:3.4.24.11] synonym: "neutral endopeptidase activity" EXACT [EC:3.4.24.11] synonym: "neutral metallendopeptidase activity" EXACT [EC:3.4.24.11] xref: EC:3.4.24.11 xref: GO:0004245 xref: MetaCyc:3.4.24.11-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000692 name: peptidyl-dipeptidase A activity namespace: molecular_function def: "Catalysis of the release of a C-terminal dipeptide, Xaa-Xbb from oligopeptide-Xaa-Xbb, when Xaa is not Pro, and Xbb is neither Asp nor Glu. Converts angiotensin I to angiotensin II." [EC:3.4.15.1] subset: gosubset_prok synonym: "ACE activity" BROAD [] synonym: "angiotensin converting enzyme" RELATED [EC:3.4.15.1] synonym: "angiotensin I-converting enzyme activity" EXACT [EC:3.4.15.1] synonym: "carboxycathepsin activity" EXACT [EC:3.4.15.1] synonym: "DCP" RELATED [EC:3.4.15.1] synonym: "dipeptide hydrolase" BROAD [EC:3.4.15.1] synonym: "dipeptidyl carboxypeptidase I activity" EXACT [EC:3.4.15.1] synonym: "endothelial cell peptidyl dipeptidase activity" EXACT [EC:3.4.15.1] synonym: "kininase II activity" EXACT [EC:3.4.15.1] synonym: "PDH" RELATED [EC:3.4.15.1] synonym: "peptidase P activity" EXACT [EC:3.4.15.1] synonym: "peptidyl dipeptidase A" RELATED [EC:3.4.15.1] synonym: "peptidyl dipeptidase I activity" EXACT [EC:3.4.15.1] synonym: "peptidyl dipeptidase-4" RELATED [EC:3.4.15.1] synonym: "peptidyl dipeptide hydrolase activity" EXACT [EC:3.4.15.1] synonym: "peptidyl-dipeptide hydrolase activity" EXACT [EC:3.4.15.1] synonym: "peptidyldipeptide hydrolase activity" EXACT [EC:3.4.15.1] xref: EC:3.4.15.1 xref: GO:0004246 xref: MetaCyc:3.4.15.1-RXN is_a: CCO:F0001787 ! metallopeptidase activity is_a: CCO:F0001791 ! peptidyl-dipeptidase activity [Term] id: CCO:F0000693 name: saccharolysin activity namespace: molecular_function def: "Catalysis of the cleavage of Pro-Phe and Ala-Ala bonds." [EC:3.4.24.37] synonym: "oligopeptidase yscD activity" NARROW [EC:3.4.24.37] synonym: "proteinase yscD activity" NARROW [EC:3.4.24.37] synonym: "saccharomyces cerevisiae proteinase yscD" RELATED [EC:3.4.24.37] synonym: "yeast cysteine proteinase D activity" NARROW [EC:3.4.24.37] xref: EC:3.4.24.37 xref: GO:0004247 xref: MetaCyc:3.4.24.37-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000694 name: stromelysin 1 activity namespace: molecular_function def: "Catalysis of the preferential cleavage where P1', P2' and P3' are hydrophobic residues." [EC:3.4.24.17] synonym: "collagen-activating protein" RELATED [EC:3.4.24.17] synonym: "collagenase activating protein" RELATED [EC:3.4.24.17] synonym: "matrix metalloproteinase 3 activity" EXACT [EC:3.4.24.17] synonym: "MMP-3" EXACT [] synonym: "neutral proteoglycanase activity" EXACT [EC:3.4.24.17] synonym: "procollagenase activator" RELATED [EC:3.4.24.17] synonym: "proteoglycanase activity" EXACT [EC:3.4.24.17] synonym: "stromelysin" RELATED [EC:3.4.24.17] synonym: "transin activity" EXACT [EC:3.4.24.17] xref: EC:3.4.24.17 xref: GO:0004248 xref: MetaCyc:3.4.24.17-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000695 name: stromelysin 3 activity namespace: molecular_function synonym: "matrix metalloproteinase 11" EXACT [] synonym: "MMP-11" EXACT [] xref: EC:3.4.24.- xref: GO:0004249 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0000696 name: aminopeptidase I activity namespace: molecular_function def: "Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates." [EC:3.4.11.22] subset: gosubset_prok synonym: "aminopeptidase III activity" EXACT [EC:3.4.11.22] synonym: "aminopeptidase yscI activity" NARROW [EC:3.4.11.22] synonym: "leucine aminopeptidase IV activity" EXACT [EC:3.4.11.22] synonym: "vacuolar aminopeptidase I activity" NARROW [EC:3.4.11.22] synonym: "yeast aminopeptidase I" RELATED [EC:3.4.11.22] xref: EC:3.4.11.22 xref: GO:0004250 xref: MetaCyc:3.4.11.22-RXN is_a: CCO:F0000646 ! aminopeptidase activity is_a: CCO:F0001785 ! metalloexopeptidase activity [Term] id: CCO:F0000697 name: X-Pro dipeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro." [EC:3.4.13.9] subset: gosubset_prok synonym: "gamma-peptidase activity" EXACT [EC:3.4.13.9] synonym: "imidodipeptidase activity" EXACT [EC:3.4.13.9] synonym: "peptidase D" RELATED [EC:3.4.13.9] synonym: "prolidase activity" EXACT [EC:3.4.13.9] synonym: "proline dipeptidase activity" EXACT [EC:3.4.13.9] synonym: "Xaa-Pro dipeptidase activity" EXACT [] xref: EC:3.4.13.9 xref: GO:0004251 xref: MetaCyc:3.4.13.9-RXN is_a: CCO:F0001785 ! metalloexopeptidase activity is_a: CCO:F0003375 ! dipeptidase activity [Term] id: CCO:F0000698 name: serine-type endopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, http://en.wikipedia.org/wiki/Serine_hydrolase, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "blood coagulation factor activity" RELATED [] xref: EC:3.4.21 xref: GO:0004252 xref: Reactome:1683 is_a: CCO:F0000644 ! endopeptidase activity is_a: CCO:F0001786 ! serine-type peptidase activity [Term] id: CCO:F0000699 name: gamma-renin activity namespace: molecular_function def: "Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide." [EC:3.4.21.54] xref: EC:3.4.21.54 xref: GO:0004253 xref: MetaCyc:3.4.21.54-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000700 name: acylaminoacyl-peptidase activity namespace: molecular_function def: "Catalysis of the reaction: acylaminoacyl-peptide + H2O = acylamino acid + peptide." [EC:3.4.19.1] subset: gosubset_prok synonym: "acylamino-acid-releasing enzyme activity" EXACT [EC:3.4.19.1] synonym: "alpha-N-acylpeptide hydrolase activity" EXACT [EC:3.4.19.1] synonym: "N-acylpeptide hydrolase activity" EXACT [EC:3.4.19.1] synonym: "N-formylmethionine (fMet) aminopeptidase activity" EXACT [EC:3.4.19.1] xref: EC:3.4.19.1 xref: GO:0004254 xref: MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000701 name: cathepsin G activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Specificity similar to chymotrypsin C." [EC:3.4.21.20] synonym: "chymotrypsin-like proteinase activity" EXACT [EC:3.4.21.20] synonym: "neutral proteinase activity" EXACT [EC:3.4.21.20] xref: EC:3.4.21.20 xref: GO:0004261 xref: MetaCyc:3.4.21.20-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000702 name: cerevisin activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides." [EC:3.4.21.48] synonym: "baker's yeast proteinase B" RELATED [EC:3.4.21.48] synonym: "brewer's yeast proteinase" NARROW [EC:3.4.21.48] synonym: "peptidase beta" RELATED [EC:3.4.21.48] synonym: "proteinase yscB activity" NARROW [EC:3.4.21.48] synonym: "yeast proteinase B activity" NARROW [EC:3.4.21.48] xref: EC:3.4.21.48 xref: GO:0004262 xref: MetaCyc:3.4.21.48-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000703 name: chymotrypsin activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Tyr-Xaa > Trp-Xaa > Phe-Xaa > Leu-Xaa." [EC:3.4.21.1, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "alpha-chymar" RELATED [EC:3.4.21.1] synonym: "alpha-chymar ophth" RELATED [EC:3.4.21.1] synonym: "alpha-chymotrypsin A" RELATED [EC:3.4.21.1] synonym: "alpha-chymotrypsin activity" NARROW [EC:3.4.21.1] synonym: "avazyme" RELATED [EC:3.4.21.1] synonym: "chymar" RELATED [EC:3.4.21.1] synonym: "chymotest" RELATED [EC:3.4.21.1] synonym: "chymotrypsin A activity" NARROW [EC:3.4.21.1] synonym: "chymotrypsin B activity" NARROW [EC:3.4.21.1] synonym: "chymotrypsins A and B" RELATED [EC:3.4.21.1] synonym: "enzeon" RELATED [EC:3.4.21.1] synonym: "quimar" RELATED [EC:3.4.21.1] synonym: "quimotrase activity" EXACT [EC:3.4.21.1] xref: EC:3.4.21.1 xref: GO:0004263 xref: MetaCyc:3.4.21.1-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000704 name: dipeptidyl-peptidase IV activity namespace: molecular_function def: "Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline." [EC:3.4.14.5] subset: gosubset_prok synonym: "amino acyl-prolyl dipeptidyl aminopeptidase activity" EXACT [EC:3.4.14.5] synonym: "dipeptidyl aminopeptidase IV activity" EXACT [EC:3.4.14.5] synonym: "dipeptidyl peptidase IV" RELATED [EC:3.4.14.5] synonym: "dipeptidyl-aminopeptidase IV" RELATED [EC:3.4.14.5] synonym: "dipeptidyl-peptide hydrolase activity" EXACT [EC:3.4.14.5] synonym: "DPP IV activity" EXACT [EC:3.4.14.5] synonym: "DPP IV/CD26" RELATED [EC:3.4.14.5] synonym: "Gly-Pro naphthylamidase activity" EXACT [EC:3.4.14.5] synonym: "glycoprotein GP110" RELATED [EC:3.4.14.5] synonym: "glycylproline aminopeptidase activity" EXACT [EC:3.4.14.5] synonym: "glycylprolyl aminopeptidase activity" EXACT [EC:3.4.14.5] synonym: "glycylprolyl dipeptidylaminopeptidase activity" EXACT [EC:3.4.14.5] synonym: "leukocyte antigen CD26" RELATED [EC:3.4.14.5] synonym: "lymphocyte antigen CD26" RELATED [EC:3.4.14.5] synonym: "pep X" RELATED [EC:3.4.14.5] synonym: "post-proline dipeptidyl aminopeptidase IV activity" EXACT [EC:3.4.14.5] synonym: "postproline dipeptidyl aminopeptidase IV" RELATED [EC:3.4.14.5] synonym: "T cell triggering molecule Tp103" RELATED [EC:3.4.14.5] synonym: "X-PDAP" RELATED [EC:3.4.14.5] synonym: "Xaa-Pro-dipeptidyl-aminopeptidase activity" EXACT [EC:3.4.14.5] synonym: "Xaa-Pro-dipeptidylaminopeptidase activity" EXACT [EC:3.4.14.5] xref: EC:3.4.14.5 xref: GO:0004274 xref: MetaCyc:3.4.14.5-RXN is_a: CCO:F0001786 ! serine-type peptidase activity is_a: CCO:F0001789 ! dipeptidyl-peptidase activity [Term] id: CCO:F0000705 name: enteropeptidase activity namespace: molecular_function def: "Catalysis of the selective cleavage of Lys6-Ile7 bond in trypsinogen." [EC:3.4.21.9] synonym: "enterokinase activity" RELATED [EC:3.4.21.9] xref: EC:3.4.21.9 xref: GO:0004275 xref: MetaCyc:3.4.21.9-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000706 name: furin activity namespace: molecular_function def: "Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors." [EC:3.4.21.75] synonym: "dibasic processing enzyme activity" EXACT [EC:3.4.21.75] synonym: "PACE" RELATED [EC:3.4.21.75] synonym: "paired basic amino acid cleaving enzyme" RELATED [EC:3.4.21.75] synonym: "paired basic amino acid converting enzyme" RELATED [EC:3.4.21.75] synonym: "paired basic amino acid residue cleaving enzyme activity" EXACT [EC:3.4.21.75] synonym: "prohormone convertase activity" NARROW [EC:3.4.21.75] synonym: "serine proteinase PACE" RELATED [EC:3.4.21.75] synonym: "SPC3" RELATED [EC:3.4.21.75] xref: EC:3.4.21.75 xref: GO:0004276 xref: MetaCyc:3.4.21.75-RXN xref: Reactome:9708 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000707 name: granzyme A activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa > Lys-Xaa > Phe-Xaa in small molecule substrates." [EC:3.4.21.78] synonym: "CTLA3" RELATED [EC:3.4.21.78] synonym: "cytotoxic T lymphocyte serine protease" NARROW [EC:3.4.21.78] synonym: "cytotoxic T-lymphocyte proteinase 1 activity" NARROW [EC:3.4.21.78] synonym: "HuTPS" RELATED [EC:3.4.21.78] synonym: "T-cell associated protease 1" RELATED [EC:3.4.21.78] synonym: "T-cell derived serine proteinase" NARROW [EC:3.4.21.78] synonym: "TSP-1" RELATED [EC:3.4.21.78] xref: EC:3.4.21.78 xref: GO:0004277 xref: MetaCyc:3.4.21.78-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000708 name: granzyme B activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Asp-Xaa > Asn-Xaa > Met-Xaa, Ser-Xaa." [EC:3.4.21.79] synonym: "CCP1 proteinase" NARROW [EC:3.4.21.79] synonym: "CCPII" RELATED [EC:3.4.21.79] synonym: "CTLA1" RELATED [EC:3.4.21.79] synonym: "cytotoxic cell proteinase-1" RELATED [EC:3.4.21.79] synonym: "cytotoxic t-lymphocyte proteinase 2 activity" NARROW [EC:3.4.21.79] synonym: "granzyme G" RELATED [EC:3.4.21.79] synonym: "granzyme H" RELATED [EC:3.4.21.79] xref: EC:3.4.21.79 xref: GO:0004278 xref: MetaCyc:3.4.21.79-RXN xref: Reactome:9714 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000709 name: pancreatic elastase II activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Leu-Xaa, Met-Xaa and Phe-Xaa. Hydrolyzes elastin." [EC:3.4.21.71] synonym: "pancreatic elastase 2" RELATED [EC:3.4.21.71] xref: EC:3.4.21.71 xref: GO:0004281 xref: MetaCyc:3.4.21.71-RXN is_a: CCO:F0001736 ! pancreatic elastase activity [Term] id: CCO:F0000710 name: plasmin activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Lys-Xaa > Arg-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products." [EC:3.4.21.7] synonym: "actase activity" EXACT [EC:3.4.21.7] synonym: "fibrinase activity" EXACT [EC:3.4.21.7] synonym: "fibrinolysin activity" EXACT [EC:3.4.21.7] synonym: "serum tryptase activity" EXACT [EC:3.4.21.7] synonym: "thrombolysin" RELATED [EC:3.4.21.7] xref: EC:3.4.21.7 xref: GO:0004283 xref: MetaCyc:3.4.21.7-RXN xref: Reactome:9727 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000711 name: acrosin activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa." [EC:3.4.21.10] synonym: "acrosin amidase activity" EXACT [EC:3.4.21.10] synonym: "acrosomal protease activity" EXACT [EC:3.4.21.10] synonym: "acrosomal proteinase activity" EXACT [EC:3.4.21.10] synonym: "acrozonase activity" EXACT [EC:3.4.21.10] synonym: "alpha-acrosin" RELATED [EC:3.4.21.10] synonym: "beta-acrosin" RELATED [EC:3.4.21.10] synonym: "psi-acrosin" RELATED [EC:3.4.21.10] xref: EC:3.4.21.10 xref: GO:0004284 xref: MetaCyc:3.4.21.10-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000712 name: proprotein convertase 1 activity namespace: molecular_function def: "Catalysis of the release of protein hormones, neuropeptides and renin from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond." [EC:3.4.21.93] synonym: "NEC 1 activity" NARROW [EC:3.4.21.93] synonym: "neuroendocrine convertase 1 activity" NARROW [EC:3.4.21.93] synonym: "PC1 activity" NARROW [EC:3.4.21.93] synonym: "prohormone convertase 3" RELATED [EC:3.4.21.93] synonym: "prohormone convertase I activity" NARROW [EC:3.4.21.93] xref: EC:3.4.21.93 xref: GO:0004285 xref: MetaCyc:3.4.21.93-RXN is_a: CCO:F0003378 ! proprotein convertase activity [Term] id: CCO:F0000713 name: proprotein convertase 2 activity namespace: molecular_function def: "Catalysis of the release of protein hormones and neuropeptides from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond." [EC:3.4.21.94] synonym: "NEC 2 activity" NARROW [EC:3.4.21.94] synonym: "neuroendocrine convertase 2 activity" NARROW [EC:3.4.21.94] synonym: "PC2 activity" NARROW [EC:3.4.21.94] synonym: "prohormone convertase II activity" NARROW [EC:3.4.21.94] xref: EC:3.4.21.94 xref: GO:0004286 xref: MetaCyc:3.4.21.94-RXN is_a: CCO:F0003378 ! proprotein convertase activity [Term] id: CCO:F0000714 name: prolyl oligopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of Pro-Xaa > Ala-Xaa in oligopeptides." [EC:3.4.21.26] subset: gosubset_prok synonym: "endoprolylpeptidase activity" EXACT [EC:3.4.21.26] synonym: "post-proline cleaving enzyme activity" EXACT [EC:3.4.21.26] synonym: "post-proline endopeptidase activity" EXACT [EC:3.4.21.26] synonym: "proline endopeptidase activity" EXACT [EC:3.4.21.26] synonym: "proline-specific endopeptidase activity" EXACT [EC:3.4.21.26] synonym: "prolyl endopeptidase activity" EXACT [EC:3.4.21.26] xref: EC:3.4.21.26 xref: GO:0004287 xref: MetaCyc:3.4.21.26-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000715 name: subtilase activity namespace: molecular_function subset: gosubset_prok xref: EC:3.4.21.- xref: GO:0004289 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000716 name: kexin activity namespace: molecular_function def: "Catalysis of the cleavage of the Arg-Xaa bond in Lys-Arg-Xaa and Arg-Arg-Xaa to process Yeast alpha-factor pheromone and killer toxin precursors." [EC:3.4.21.61] synonym: "andrenorphin-Gly-generating enzyme" RELATED [EC:3.4.21.61] synonym: "endoproteinase Kex2p" RELATED [EC:3.4.21.61] synonym: "gene KEX2 dibasic proteinase" NARROW [EC:3.4.21.61] synonym: "Kex 2p proteinase" NARROW [EC:3.4.21.61] synonym: "Kex2 endopeptidase" NARROW [EC:3.4.21.61] synonym: "Kex2 endoprotease" NARROW [EC:3.4.21.61] synonym: "Kex2 endoproteinase" NARROW [EC:3.4.21.61] synonym: "Kex2 protease" NARROW [EC:3.4.21.61] synonym: "Kex2 proteinase" NARROW [EC:3.4.21.61] synonym: "Kex2-like endoproteinase" NARROW [EC:3.4.21.61] synonym: "Kex2-like precursor protein processing endoprotease" NARROW [EC:3.4.21.61] synonym: "paired-basic endopeptidase activity" EXACT [EC:3.4.21.61] synonym: "prohormone-processing endoprotease activity" RELATED [EC:3.4.21.61] synonym: "prohormone-processing KEX2 proteinase" NARROW [EC:3.4.21.61] synonym: "prohormone-processing proteinase activity" EXACT [EC:3.4.21.61] synonym: "protease KEX2" RELATED [EC:3.4.21.61] synonym: "proteinase Kex2p" RELATED [EC:3.4.21.61] synonym: "proteinase yscF activity" NARROW [EC:3.4.21.61] synonym: "yeast cysteine proteinase F" RELATED [EC:3.4.21.61] synonym: "yeast KEX2 protease activity" NARROW [EC:3.4.21.61] xref: EC:3.4.21.61 xref: GO:0004290 xref: MetaCyc:3.4.21.61-RXN is_a: CCO:F0000715 ! subtilase activity [Term] id: CCO:F0000717 name: subtilisin activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides." [EC:3.4.21.62] subset: gosubset_prok synonym: "alcalase 0.6L" RELATED [EC:3.4.21.62] synonym: "alcalase 2.5L" RELATED [EC:3.4.21.62] synonym: "alcalase activity" EXACT [EC:3.4.21.62] synonym: "ALK-enzyme" RELATED [EC:3.4.21.62] synonym: "bacillopeptidase A" RELATED [EC:3.4.21.62] synonym: "bacillopeptidase B" RELATED [EC:3.4.21.62] synonym: "bacillus subtilis alkaline proteinase activity" EXACT [EC:3.4.21.62] synonym: "bacillus subtilis alkaline proteinase bioprase activity" EXACT [EC:3.4.21.62] synonym: "bioprase AL 15" RELATED [EC:3.4.21.62] synonym: "bioprase APL 30" RELATED [EC:3.4.21.62] synonym: "colistinase activity" EXACT [EC:3.4.21.62] synonym: "esperase activity" EXACT [EC:3.4.21.62] synonym: "genenase I" RELATED [EC:3.4.21.62] synonym: "kazusase activity" EXACT [EC:3.4.21.62] synonym: "maxatase activity" EXACT [EC:3.4.21.62] synonym: "opticlean" RELATED [EC:3.4.21.62] synonym: "orientase 10B" RELATED [EC:3.4.21.62] synonym: "protease S" RELATED [EC:3.4.21.62] synonym: "protease VIII" RELATED [EC:3.4.21.62] synonym: "protease XXVII" RELATED [EC:3.4.21.62] synonym: "protin A 3L" RELATED [EC:3.4.21.62] synonym: "savinase 16.0L" RELATED [EC:3.4.21.62] synonym: "savinase 32.0 L EX" RELATED [EC:3.4.21.62] synonym: "savinase 4.0T" RELATED [EC:3.4.21.62] synonym: "savinase 8.0L" RELATED [EC:3.4.21.62] synonym: "savinase activity" EXACT [EC:3.4.21.62] synonym: "SP 266" RELATED [EC:3.4.21.62] synonym: "subtilisin BL" RELATED [EC:3.4.21.62] synonym: "subtilisin DY" RELATED [EC:3.4.21.62] synonym: "subtilisin E" RELATED [EC:3.4.21.62] synonym: "subtilisin GX" RELATED [EC:3.4.21.62] synonym: "subtilisin J" RELATED [EC:3.4.21.62] synonym: "subtilisin S41" RELATED [EC:3.4.21.62] synonym: "subtilisin sendai" RELATED [EC:3.4.21.62] synonym: "subtilopeptidase activity" EXACT [EC:3.4.21.62] synonym: "superase activity" EXACT [EC:3.4.21.62] synonym: "thermoase" BROAD [EC:3.4.21.62] synonym: "thermoase PC 10" RELATED [EC:3.4.21.62] xref: EC:3.4.21.62 xref: GO:0004291 xref: MetaCyc:3.4.21.62-RXN is_a: CCO:F0000715 ! subtilase activity [Term] id: CCO:F0000718 name: tissue kallikrein activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds." [EC:3.4.21.35] synonym: "bradykininogenase" BROAD [EC:3.4.21.35] synonym: "callicrein" RELATED [EC:3.4.21.35] synonym: "depot-padutin" RELATED [EC:3.4.21.35] synonym: "dilminal D" RELATED [EC:3.4.21.35] synonym: "glandular kallikrein activity" RELATED [EC:3.4.21.35] synonym: "glumorin" RELATED [EC:3.4.21.35] synonym: "kallidinogenase" BROAD [EC:3.4.21.35] synonym: "kallikrein" RELATED [EC:3.4.21.35] synonym: "kidney kallikrein" RELATED [EC:3.4.21.35] synonym: "kininogenase" BROAD [EC:3.4.21.35] synonym: "kininogenin activity" RELATED [EC:3.4.21.35] synonym: "onokrein P" RELATED [EC:3.4.21.35] synonym: "padreatin" RELATED [EC:3.4.21.35] synonym: "padutin" RELATED [EC:3.4.21.35] synonym: "pancreatic kallikrein" RELATED [EC:3.4.21.35] synonym: "salivary kallikrein" RELATED [EC:3.4.21.35] synonym: "submandibular kallikrein" RELATED [EC:3.4.21.35] synonym: "submaxillary kallikrein" RELATED [EC:3.4.21.35] synonym: "urinary kallikrein" RELATED [EC:3.4.21.35] synonym: "urokallikrein" RELATED [EC:3.4.21.35] xref: EC:3.4.21.35 xref: GO:0004279 xref: GO:0004293 xref: MetaCyc:3.4.21.35-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000719 name: tripeptidyl-peptidase II activity namespace: molecular_function def: "Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH." [EC:3.4.14.10] synonym: "TPP" RELATED [EC:3.4.14.10] synonym: "tripeptidyl aminopeptidase activity" BROAD [EC:3.4.14.10] synonym: "tripeptidyl aminopeptidase II" RELATED [EC:3.4.14.10] synonym: "tripeptidyl peptidase activity" BROAD [EC:3.4.14.10] synonym: "tripeptidyl peptidase II" RELATED [EC:3.4.14.10] xref: EC:3.4.14.10 xref: GO:0004294 xref: MetaCyc:3.4.14.10-RXN is_a: CCO:F0001790 ! tripeptidyl-peptidase activity [Term] id: CCO:F0000720 name: trypsin activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa." [EC:3.4.21.4] subset: gosubset_prok synonym: "alpha-trypsin activity" NARROW [EC:3.4.21.4] synonym: "beta-trypsin activity" NARROW [EC:3.4.21.4] synonym: "cocoonase activity" EXACT [EC:3.4.21.4] synonym: "parenzyme" RELATED [EC:3.4.21.4] synonym: "parenzymol" RELATED [EC:3.4.21.4] synonym: "pseudotrypsin" RELATED [EC:3.4.21.4] synonym: "sperm receptor hydrolase activity" EXACT [EC:3.4.21.4] synonym: "tripcellim" RELATED [EC:3.4.21.4] synonym: "tryptar" RELATED [EC:3.4.21.4] synonym: "trypure" RELATED [EC:3.4.21.4] xref: EC:3.4.21.4 xref: GO:0004295 xref: MetaCyc:3.4.21.4-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0000721 name: threonine endopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which threonine residues act as nucleophiles." [EC:3.4.25.1, GOC:mah] subset: gosubset_prok synonym: "26S protease" NARROW [EC:3.4.25] synonym: "alkaline protease" RELATED [EC:3.4.25] synonym: "ingensin" RELATED [EC:3.4.25] synonym: "large multicatalytic protease" NARROW [EC:3.4.25] synonym: "lens neutral proteinase" NARROW [EC:3.4.25] synonym: "MCP" RELATED [EC:3.4.25] synonym: "multicatalytic endopeptidase complex" RELATED [EC:3.4.25] synonym: "multicatalytic proteinase" NARROW [EC:3.4.25] synonym: "multicatalytic proteinase (complex)" NARROW [EC:3.4.25] synonym: "prosome" RELATED [EC:3.4.25] synonym: "proteasome endopeptidase complex" NARROW [EC:3.4.25] synonym: "tricorn protease" NARROW [EC:3.4.25] synonym: "tricorn proteinase" NARROW [EC:3.4.25] xref: EC:3.4.25 xref: GO:0004298 is_a: CCO:F0000644 ! endopeptidase activity [Term] id: CCO:F0000722 name: enoyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O." [EC:4.2.1.17] subset: gosubset_prok synonym: "(3S)-3-hydroxyacyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.17] synonym: "2-enoyl-CoA hydratase activity" EXACT [EC:4.2.1.17] synonym: "2-octenoyl coenzyme A hydrase activity" EXACT [EC:4.2.1.17] synonym: "acyl coenzyme A hydrase activity" EXACT [EC:4.2.1.17] synonym: "beta-hydroxyacid dehydrase activity" EXACT [EC:4.2.1.17] synonym: "beta-hydroxyacyl-CoA dehydrase activity" EXACT [EC:4.2.1.17] synonym: "crotonyl hydrase activity" EXACT [EC:4.2.1.17] synonym: "D-3-hydroxyacyl-CoA dehydratase" BROAD [EC:4.2.1.17] synonym: "ECH" RELATED [EC:4.2.1.17] synonym: "enol-CoA hydratase activity" EXACT [EC:4.2.1.17] synonym: "enoyl coenzyme A hydrase (D)" BROAD [EC:4.2.1.17] synonym: "enoyl coenzyme A hydrase (L)" EXACT [EC:4.2.1.17] synonym: "enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.17] synonym: "enoyl hydrase activity" EXACT [EC:4.2.1.17] synonym: "hydratase, enoyl coenzyme A" EXACT [EC:4.2.1.17] synonym: "short chain enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.17] synonym: "short-chain enoyl-CoA hydratase activity" EXACT [] synonym: "trans-2-enoyl-CoA hydratase activity" EXACT [EC:4.2.1.17] synonym: "unsaturated acyl-CoA hydratase activity" EXACT [EC:4.2.1.17] xref: EC:4.2.1.17 xref: GO:0004300 xref: GO:0016510 xref: MetaCyc:ENOYL-COA-HYDRAT-RXN xref: Reactome:10287 xref: UM-BBD_enzymeID:e0014 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000723 name: epoxide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: an epoxide + H2O = a glycol." [EC:3.3.2.10] subset: gosubset_prok synonym: "arene-oxide hydratase activity" BROAD [EC:3.3.2.10] synonym: "aryl epoxide hydrase activity" BROAD [EC:3.3.2.10] synonym: "cytosolic epoxide hydrolase activity" EXACT [EC:3.3.2.10] synonym: "epoxide hydrase activity" BROAD [EC:3.3.2.10] synonym: "epoxide hydratase activity" BROAD [EC:3.3.2.10] synonym: "sEH" RELATED [EC:3.3.2.10] synonym: "soluble epoxide hydrolase activity" NARROW [EC:3.3.2.10] synonym: "trans-stilbene oxide hydrolase activity" EXACT [EC:3.3.2.10] xref: EC:3.3.2.10 xref: GO:0004301 xref: MetaCyc:3.3.2.10-RXN xref: UM-BBD_enzymeID:e0397 is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0000724 name: estradiol 17-beta-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+." [EC:1.1.1.62] synonym: "17-beta-estradiol dehydrogenase activity" EXACT [EC:1.1.1.62] synonym: "17-beta-HSD activity" BROAD [EC:1.1.1.62] synonym: "17-beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.62] synonym: "17beta,20alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.62] synonym: "17beta-estradiol dehydrogenase activity" EXACT [EC:1.1.1.62] synonym: "17beta-HSD" RELATED [EC:1.1.1.62] synonym: "17beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.62] synonym: "20alpha-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.62] synonym: "estradiol 17beta-dehydrogenase activity" EXACT [EC:1.1.1.62] synonym: "estradiol dehydrogenase activity" EXACT [EC:1.1.1.62] synonym: "estradiol-17beta:NAD(P)+ 17-oxidoreductase activity" EXACT [EC:1.1.1.62] synonym: "estrogen 17-oxidoreductase activity" EXACT [EC:1.1.1.62] xref: EC:1.1.1.62 xref: GO:0004303 xref: MetaCyc:ESTRADIOL-17-BETA-DEHYDROGENASE-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000725 name: estrone sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate." [EC:2.8.2.4] synonym: "3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase activity" EXACT [EC:2.8.2.4] synonym: "3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase activity" EXACT [EC:2.8.2.4] synonym: "3'-phosphoadenylylsulfate:oestrone sulfotransferase activity" EXACT [EC:2.8.2.4] synonym: "estrogen sulfotransferase" BROAD [EC:2.8.2.4] synonym: "estrogen sulphotransferase activity" EXACT [EC:2.8.2.4] synonym: "estrone sulphotransferase activity" EXACT [] synonym: "oestrogen sulphotransferase activity" EXACT [EC:2.8.2.4] xref: EC:2.8.2.4 xref: GO:0004304 xref: MetaCyc:ESTRONE-SULFOTRANSFERASE-RXN xref: Reactome:10293 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0000726 name: ethanolamine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + ethanolamine = ADP + O-phosphoethanolamine." [EC:2.7.1.82] synonym: "ATP:ethanolamine O-phosphotransferase activity" EXACT [EC:2.7.1.82] synonym: "ethanolamine kinase (phosphorylating)" EXACT [EC:2.7.1.82] synonym: "ethanolamine phosphokinase activity" EXACT [EC:2.7.1.82] xref: EC:2.7.1.82 xref: GO:0004305 xref: MetaCyc:ETHANOLAMINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000727 name: ethanolamine-phosphate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine." [EC:2.7.7.14] synonym: "CTP-phosphoethanolamine cytidylyltransferase activity" EXACT [EC:2.7.7.14] synonym: "CTP:ethanolamine-phosphate cytidylyltransferase activity" EXACT [] synonym: "CTP:phosphoethanolamine cytidylyltransferase activity" EXACT [EC:2.7.7.14] synonym: "ET" RELATED [EC:2.7.7.14] synonym: "ethanolamine phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.14] synonym: "phosphoethanolamine cytidylyltransferase activity" EXACT [] synonym: "phosphorylethanolamine transferase activity" BROAD [EC:2.7.7.14] xref: EC:2.7.7.14 xref: GO:0004306 xref: MetaCyc:2.7.7.14-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000728 name: ethanolaminephosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine." [EC:2.7.8.1] synonym: "CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity" EXACT [EC:2.7.8.1] synonym: "CDPethanolamine diglyceride phosphotransferase activity" EXACT [EC:2.7.8.1] synonym: "diacylglycerol ethanolaminephosphotransferase activity" EXACT [EC:2.7.8.1] synonym: "EPT" RELATED [EC:2.7.8.1] synonym: "phosphorylethanolamine-glyceride transferase activity" EXACT [EC:2.7.8.1] xref: EC:2.7.8.1 xref: GO:0004307 xref: MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN is_a: CCO:F0003607 ! CDP-alcohol phosphatidyltransferase activity [Term] id: CCO:F0000729 name: exo-alpha-sialidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates." [EC:3.2.1.18] subset: gosubset_prok synonym: "acetylneuraminidase activity" EXACT [EC:3.2.1.18] synonym: "acetylneuraminyl hydrolase activity" EXACT [EC:3.2.1.18] synonym: "alpha-neuraminidase activity" EXACT [EC:3.2.1.18] synonym: "N-acylneuraminate glycohydrolase activity" EXACT [EC:3.2.1.18] synonym: "neuraminidase activity" EXACT [EC:3.2.1.18] synonym: "sialidase activity" EXACT [EC:3.2.1.18] xref: EC:3.2.1.18 xref: GO:0004308 xref: MetaCyc:3.2.1.18-RXN is_a: CCO:F0003509 ! alpha-sialidase activity [Term] id: CCO:F0000730 name: exopolyphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate." [EC:3.6.1.11] subset: gosubset_prok synonym: "acid phosphoanhydride phosphohydrolase activity" EXACT [EC:3.6.1.11] synonym: "exopolypase activity" EXACT [EC:3.6.1.11] synonym: "Gra-pase activity" EXACT [EC:3.6.1.11] synonym: "metaphosphatase activity" BROAD [EC:3.6.1.11] synonym: "polyphosphate phosphohydrolase activity" EXACT [EC:3.6.1.11] xref: EC:3.6.1.11 xref: GO:0004309 xref: MetaCyc:EXOPOLYPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0000731 name: farnesyl-diphosphate farnesyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate." [EC:2.5.1.21] subset: gosubset_prok synonym: "farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity" EXACT [EC:2.5.1.21] synonym: "farnesyltransferase activity" BROAD [EC:2.5.1.21] synonym: "presqualene synthase activity" EXACT [EC:2.5.1.21] synonym: "presqualene-diphosphate synthase activity" EXACT [EC:2.5.1.21] synonym: "squalene synthase activity" EXACT [EC:2.5.1.21] synonym: "squalene synthetase activity" EXACT [EC:2.5.1.21] xref: EC:2.5.1.21 xref: GO:0004310 xref: MetaCyc:2.5.1.21-RXN xref: Reactome:10334 is_a: CCO:F0000732 ! farnesyltranstransferase activity [Term] id: CCO:F0000732 name: farnesyltranstransferase activity namespace: molecular_function def: "Catalysis of the reaction: trans,trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate." [EC:2.5.1.29] subset: gosubset_prok synonym: "farnesyltransferase activity" BROAD [EC:2.5.1.29] synonym: "geranylgeranyl pyrophosphate synthase activity" EXACT [EC:2.5.1.29] synonym: "geranylgeranyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.29] synonym: "geranylgeranyl-diphosphate synthase activity" EXACT [EC:2.5.1.29] synonym: "geranylgeranyl-PP synthetase activity" EXACT [EC:2.5.1.29] synonym: "trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity" EXACT [EC:2.5.1.29] xref: EC:2.5.1.29 xref: GO:0004311 xref: MetaCyc:FARNESYLTRANSTRANSFERASE-RXN xref: Reactome:10335 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0000733 name: fatty-acid synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+." [EC:2.3.1.85] subset: gosubset_prok synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)" EXACT [EC:2.3.1.85] xref: EC:2.3.1.85 xref: GO:0004312 xref: MetaCyc:FATTY-ACID-SYNTHASE-RXN is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0000736 name: 3-oxoacyl-[acyl-carrier-protein] synthase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]." [EC:2.3.1.41] subset: gosubset_prok synonym: "3-ketoacyl-acyl carrier protein synthase activity" EXACT [EC:2.3.1.41] synonym: "3-oxoacyl-[acyl-carrier protein] synthase activity" EXACT [] synonym: "3-oxoacyl-ACP synthase activity" EXACT [] synonym: "3-oxoacyl-acyl-carrier-protein synthase activity" EXACT [EC:2.3.1.41] synonym: "3-oxoacyl:ACP synthase I" RELATED [EC:2.3.1.41] synonym: "acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)" EXACT [EC:2.3.1.41] synonym: "acyl-malonyl acyl carrier protein-condensing enzyme activity" EXACT [EC:2.3.1.41] synonym: "acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl acyl carrier protein synthase activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl synthetase activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl-[acyl carrier protein] synthase activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl-ACP synthase I activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl-ACP synthetase activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl-acyl carrier protein synthase activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl-acyl carrier protein synthetase activity" EXACT [EC:2.3.1.41] synonym: "beta-ketoacyl-acyl-carrier-protein synthase I" RELATED [EC:2.3.1.41] synonym: "beta-ketoacylsynthase activity" EXACT [EC:2.3.1.41] synonym: "condensing enzyme activity" BROAD [EC:2.3.1.41] synonym: "FabB" RELATED [EC:2.3.1.41] synonym: "FabF1" RELATED [EC:2.3.1.41] synonym: "fatty acid condensing enzyme activity" BROAD [EC:2.3.1.41] synonym: "KAS I activity" NARROW [EC:2.3.1.41] synonym: "KASI" RELATED [EC:2.3.1.41] synonym: "ketoacyl-ACP synthase activity" EXACT [] xref: EC:2.3.1.41 xref: GO:0004315 xref: MetaCyc:3-OXOACYL-ACP-SYNTH-RXN xref: Reactome:76136 is_a: CCO:F0000733 ! fatty-acid synthase activity [Term] id: CCO:F0000737 name: 3-oxoacyl-[acyl-carrier-protein] reductase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+." [EC:1.1.1.100] subset: gosubset_prok synonym: "(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.100] synonym: "3-ketoacyl acyl carrier protein reductase activity" EXACT [EC:1.1.1.100] synonym: "3-oxoacyl-[acyl-carrier protein] reductase activity" EXACT [] synonym: "3-oxoacyl-ACP reductase activity" EXACT [] synonym: "3-oxoacyl-ACPreductase activity" EXACT [EC:1.1.1.100] synonym: "3-oxoacyl-acyl-carrier-protein reductase activity" EXACT [EC:1.1.1.100] synonym: "beta-ketoacyl acyl carrier protein (ACP) reductase activity" EXACT [EC:1.1.1.100] synonym: "beta-ketoacyl reductase activity" EXACT [EC:1.1.1.100] synonym: "beta-ketoacyl thioester reductase activity" EXACT [EC:1.1.1.100] synonym: "beta-ketoacyl-ACP reductase activity" EXACT [EC:1.1.1.100] synonym: "beta-ketoacyl-acyl carrier protein reductase activity" EXACT [EC:1.1.1.100] synonym: "beta-ketoacyl-acyl-carrier protein(ACP) reductase activity" EXACT [EC:1.1.1.100] synonym: "NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity" EXACT [EC:1.1.1.100] xref: EC:1.1.1.100 xref: GO:0004316 xref: MetaCyc:3-OXOACYL-ACP-REDUCT-RXN xref: Reactome:76148 is_a: CCO:F0000733 ! fatty-acid synthase activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000738 name: 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O." [EC:4.2.1.61] synonym: "(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase activity" EXACT [EC:4.2.1.61] synonym: "(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase (hexadec-2-enoyl-acyl-carrier protein-forming)" EXACT [EC:4.2.1.61] synonym: "(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase activity" EXACT [EC:4.2.1.61] synonym: "3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity" EXACT [] synonym: "3-hydroxypalmitoyl-ACP dehydratase activity" EXACT [] synonym: "3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.61] synonym: "beta-hydroxypalmitoyl thioester dehydratase activity" EXACT [EC:4.2.1.61] synonym: "beta-hydroxypalmitoyl-acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.61] synonym: "beta-hydroxypalmityl-ACP dehydrase activity" EXACT [EC:4.2.1.61] synonym: "D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity" EXACT [EC:4.2.1.61] synonym: "D-3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.61] xref: EC:4.2.1.61 xref: GO:0004317 xref: MetaCyc:4.2.1.61-RXN is_a: CCO:F0000733 ! fatty-acid synthase activity is_a: CCO:F0004104 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [Term] id: CCO:F0000739 name: enoyl-[acyl-carrier-protein] reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+." [EC:1.3.1.9] subset: gosubset_prok synonym: "acyl-acyl-carrier-protein:NAD+ oxidoreductase" EXACT [EC:1.3.1.9] synonym: "enoyl-[acyl-carrier protein] reductase (NADH) activity" EXACT [EC:1.3.1.9] synonym: "enoyl-ACP reductase (NADH) activity" EXACT [EC:1.3.1.9] synonym: "enoyl-acyl-carrier-protein reductase (NADH)" EXACT [EC:1.3.1.9] synonym: "NADH-enoyl acyl carrier protein reductase activity" EXACT [EC:1.3.1.9] synonym: "NADH-specific enoyl-ACP reductase activity" EXACT [EC:1.3.1.9] xref: EC:1.3.1.9 xref: GO:0004318 xref: MetaCyc:ENOYL-ACP-REDUCT-NADH-RXN is_a: CCO:F0000733 ! fatty-acid synthase activity is_a: CCO:F0003232 ! enoyl-[acyl-carrier-protein] reductase activity [Term] id: CCO:F0000740 name: enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+." [EC:1.3.1.10] subset: gosubset_prok synonym: "acyl-acyl-carrier-protein:NADP+ oxidoreductase (B-specific)" EXACT [EC:1.3.1.10] synonym: "enoyl acyl-carrier-protein reductase activity" EXACT [EC:1.3.1.10] synonym: "enoyl-[acyl-carrier protein] reductase (NADPH, B-specific) activity" EXACT [] synonym: "enoyl-ACP reductase (NADPH, B-specific) activity" EXACT [] synonym: "enoyl-acyl-carrier-protein reductase (NADPH, B-specific)" EXACT [EC:1.3.1.10] synonym: "enoyl-acyl-carrier-protein reductase (NADPH2, B-specific)" EXACT [EC:1.3.1.10] synonym: "NADPH 2-enoyl Co A reductase activity" EXACT [EC:1.3.1.10] synonym: "reductase, enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.3.1.10] xref: EC:1.3.1.10 xref: GO:0004319 xref: MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN xref: Reactome:76151 is_a: CCO:F0000733 ! fatty-acid synthase activity is_a: CCO:F0003232 ! enoyl-[acyl-carrier-protein] reductase activity [Term] id: CCO:F0000741 name: oleoyl-[acyl-carrier-protein] hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate." [EC:3.1.2.14] subset: gosubset_prok synonym: "oleoyl-[acyl-carrier protein] hydrolase activity" EXACT [] synonym: "oleoyl-ACP hydrolase activity" EXACT [] synonym: "oleoyl-ACP thioesterase activity" EXACT [EC:3.1.2.14] synonym: "oleoyl-acyl carrier protein thioesterase activity" EXACT [EC:3.1.2.14] synonym: "oleoyl-acyl-carrier-protein hydrolase" BROAD [EC:3.1.2.14] xref: EC:3.1.2.14 xref: GO:0004320 xref: MetaCyc:3.1.2.14-RXN xref: MetaCyc:PWY-5142 xref: Reactome:76154 is_a: CCO:F0003110 ! acyl-[acyl-carrier-protein] hydrolase activity [Term] id: CCO:F0000742 name: fatty-acyl-CoA synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+." [EC:2.3.1.86] synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing)" EXACT [EC:2.3.1.86] synonym: "yeast fatty acid synthase activity" NARROW [EC:2.3.1.86] xref: EC:2.3.1.86 xref: GO:0004321 xref: MetaCyc:FATTY-ACYL-COA-SYNTHASE-RXN is_a: CCO:F0003131 ! C-acyltransferase activity [Term] id: CCO:F0000743 name: ferroxidase activity namespace: molecular_function def: "Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O." [EC:1.16.3.1] subset: gosubset_prok synonym: "caeruloplasmin" RELATED [EC:1.16.3.1] synonym: "ceruloplasmin activity" NARROW [EC:1.16.3.1] synonym: "Fe(II):oxygen oxidoreductase activity" EXACT [EC:1.16.3.1] synonym: "ferro:O2 oxidoreductase activity" EXACT [EC:1.16.3.1] synonym: "ferroxidase I" RELATED [EC:1.16.3.1] synonym: "ferroxidase, iron II:oxygen oxidoreductase activity" EXACT [EC:1.16.3.1] synonym: "iron(II): oxygen oxidoreductase activity" EXACT [EC:1.16.3.1] synonym: "multicopper ferroxidase iron transport mediator activity" NARROW [] xref: EC:1.16.3.1 xref: GO:0004322 xref: MetaCyc:RXN0-1483 is_a: CCO:F0003306 ! oxidoreductase activity, oxidizing metal ions, oxygen as acceptor [Term] id: CCO:F0000744 name: ferredoxin-NADP+ reductase activity namespace: molecular_function def: "Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+." [EC:1.18.1.2, GOC:kd] comment: Note that this term specifically refers to the reaction proceeding in the direction shown; it should therefore be used to annotate gene products that catalyze the oxidation of reduced ferredoxin or adrenodoxin; also consider annotating to the molecular function term 'NADPH-adrenodoxin reductase activity ; GO:0015039'. subset: gosubset_prok synonym: "ferredoxin-NADP oxidoreductase activity" EXACT [EC:1.18.1.2] synonym: "ferredoxin-NADP reductase activity" EXACT [] synonym: "ferredoxin-NADP-oxidoreductase activity" EXACT [EC:1.18.1.2] synonym: "ferredoxin-nicotinamide adenine dinucleotide phosphate reductase activity" EXACT [EC:1.18.1.2] synonym: "ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase activity" EXACT [EC:1.18.1.2] synonym: "ferredoxin-TPN reductase activity" EXACT [EC:1.18.1.2] synonym: "ferredoxin:NADP+ oxidoreductase activity" EXACT [EC:1.18.1.2] synonym: "NADP:ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.2] synonym: "NADPH:ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.2] synonym: "reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase activity" EXACT [EC:1.18.1.2] synonym: "TPNH-ferredoxin reductase activity" EXACT [EC:1.18.1.2] xref: EC:1.18.1.2 xref: GO:0004324 is_a: CCO:F0002273 ! ferredoxin reductase activity [Term] id: CCO:F0000745 name: ferrochelatase activity namespace: molecular_function def: "Catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+." [EC:4.99.1.1] subset: gosubset_prok synonym: "ferro-protoporphyrin chelatase activity" EXACT [EC:4.99.1.1] synonym: "heme synthase activity" EXACT [EC:4.99.1.1] synonym: "heme synthetase activity" EXACT [EC:4.99.1.1] synonym: "iron chelatase activity" EXACT [EC:4.99.1.1] synonym: "protoheme ferro-lyase (protoporphyrin-forming)" EXACT [EC:4.99.1.1] synonym: "protoheme ferro-lyase activity" EXACT [EC:4.99.1.1] synonym: "protoheme ferrolyase activity" EXACT [EC:4.99.1.1] xref: EC:4.99.1.1 xref: GO:0004325 xref: MetaCyc:PROTOHEMEFERROCHELAT-RXN xref: Reactome:10394 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0000746 name: tetrahydrofolylpolyglutamate synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1)." [EC:6.3.2.17] subset: gosubset_prok synonym: "folate polyglutamate synthetase activity" EXACT [EC:6.3.2.17] synonym: "folylpoly(gamma-glutamate) synthase activity" EXACT [EC:6.3.2.17] synonym: "folylpoly-gamma-glutamate synthase activity" EXACT [EC:6.3.2.17] synonym: "folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity" EXACT [EC:6.3.2.17] synonym: "folylpolyglutamate synthase activity" EXACT [] synonym: "folylpolyglutamate synthetase activity" EXACT [EC:6.3.2.17] synonym: "folylpolyglutamyl synthetase activity" EXACT [EC:6.3.2.17] synonym: "formyltetrahydropteroyldiglutamate synthetase activity" EXACT [EC:6.3.2.17] synonym: "FPGS activity" EXACT [EC:6.3.2.17] synonym: "N(10)-formyltetrahydropteroyldiglutamate synthetase activity" EXACT [EC:6.3.2.17] synonym: "N10-formyltetrahydropteroyldiglutamate synthetase activity" EXACT [EC:6.3.2.17] synonym: "tetrahydrofolate synthase activity" EXACT [EC:6.3.2.17] synonym: "tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity" EXACT [EC:6.3.2.17] synonym: "tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.17] synonym: "tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.17] xref: EC:6.3.2.17 xref: GO:0004326 xref: MetaCyc:FOLYLPOLYGLUTAMATESYNTH-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0000748 name: formamidase activity namespace: molecular_function def: "Catalysis of the reaction: formamide + H2O = formate + NH3." [EC:3.5.1.49] subset: gosubset_prok synonym: "formamide amidohydrolase activity" EXACT [EC:3.5.1.49] xref: EC:3.5.1.49 xref: GO:0004328 xref: MetaCyc:FORMAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000749 name: formate-tetrahydrofolate ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate." [EC:6.3.4.3] subset: gosubset_prok synonym: "10-formyltetrahydrofolate synthetase activity" EXACT [EC:6.3.4.3] synonym: "formate:tetrahydrofolate ligase (ADP-forming)" EXACT [EC:6.3.4.3] synonym: "formyltetrahydrofolate synthetase activity" EXACT [EC:6.3.4.3] synonym: "tetrahydrofolate formylase activity" EXACT [EC:6.3.4.3] synonym: "tetrahydrofolic formylase activity" EXACT [EC:6.3.4.3] xref: EC:6.3.4.3 xref: GO:0004329 xref: MetaCyc:FORMATETHFLIG-RXN is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0000750 name: fructose-2,6-bisphosphate 2-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [EC:3.1.3.46] subset: gosubset_prok synonym: "beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase activity" EXACT [EC:3.1.3.46] synonym: "D-fructose-2,6-bisphosphate 2-phosphohydrolase activity" EXACT [EC:3.1.3.46] synonym: "fructose-2,6-bisphosphatase activity" EXACT [EC:3.1.3.46] xref: EC:3.1.3.46 xref: GO:0004330 xref: GO:0004331 xref: MetaCyc:3.1.3.46-RXN xref: Reactome:10434 is_a: CCO:F0004126 ! carbohydrate phosphatase activity [Term] id: CCO:F0000751 name: fructose-bisphosphate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate." [EC:4.1.2.13] subset: gosubset_prok synonym: "1,6-diphosphofructose aldolase activity" EXACT [EC:4.1.2.13] synonym: "aldolase activity" BROAD [EC:4.1.2.13] synonym: "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.13] synonym: "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.13] synonym: "diphosphofructose aldolase activity" EXACT [EC:4.1.2.13] synonym: "fructoaldolase activity" EXACT [EC:4.1.2.13] synonym: "fructose 1,6-diphosphate aldolase activity" EXACT [EC:4.1.2.13] synonym: "fructose 1-monophosphate aldolase activity" EXACT [EC:4.1.2.13] synonym: "fructose 1-phosphate aldolase activity" EXACT [EC:4.1.2.13] synonym: "fructose diphosphate aldolase activity" EXACT [EC:4.1.2.13] synonym: "fructose-1,6-bisphosphate triosephosphate-lyase activity" EXACT [EC:4.1.2.13] synonym: "ketose 1-phosphate aldolase activity" EXACT [EC:4.1.2.13] synonym: "phosphofructoaldolase activity" EXACT [EC:4.1.2.13] synonym: "SMALDO" RELATED [EC:4.1.2.13] synonym: "zymohexase activity" EXACT [EC:4.1.2.13] xref: EC:4.1.2.13 xref: GO:0004332 xref: MetaCyc:F16ALDOLASE-RXN xref: Reactome:10435 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0000752 name: fumarate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate = fumarate + H2O." [EC:4.2.1.2] subset: gosubset_prok synonym: "(S)-malate hydro-lyase (fumarate-forming)" EXACT [EC:4.2.1.2] synonym: "(S)-malate hydro-lyase activity" EXACT [EC:4.2.1.2] synonym: "fumarase activity" EXACT [EC:4.2.1.2] synonym: "L-malate hydro-lyase activity" EXACT [EC:4.2.1.2] xref: EC:4.2.1.2 xref: GO:0004333 xref: MetaCyc:FUMHYDR-RXN xref: Reactome:10436 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000753 name: fumarylacetoacetase activity namespace: molecular_function def: "Catalysis of the reaction: 4-fumarylacetoacetate + H2O = acetoacetate + fumarate." [EC:3.7.1.2] subset: gosubset_prok synonym: "4-fumarylacetoacetate fumarylhydrolase activity" EXACT [EC:3.7.1.2] synonym: "beta-diketonase activity" EXACT [EC:3.7.1.2] synonym: "fumarylacetoacetate hydrolase activity" EXACT [EC:3.7.1.2] xref: EC:3.7.1.2 xref: GO:0004334 xref: MetaCyc:FUMARYLACETOACETASE-RXN xref: Reactome:10438 xref: UM-BBD_enzymeID:e0083 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0000754 name: galactokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-galactose = ADP + D-galactose 1-phosphate." [EC:2.7.1.6] subset: gosubset_prok synonym: "ATP:D-galactose 1-phosphotransferase activity" EXACT [EC:2.7.1.6] synonym: "ATP:D-galactose-1-phosphotransferase activity" EXACT [EC:2.7.1.6] synonym: "galactokinase (phosphorylating)" EXACT [EC:2.7.1.6] xref: EC:2.7.1.6 xref: GO:0004335 xref: MetaCyc:GALACTOKIN-RXN xref: Reactome:10440 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0000755 name: galactosylceramidase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine." [EC:3.2.1.46] synonym: "beta-galactocerebrosidase activity" EXACT [EC:3.2.1.46] synonym: "beta-galactosylceramidase activity" EXACT [EC:3.2.1.46] synonym: "ceramide galactosidase activity" EXACT [EC:3.2.1.46] synonym: "cerebroside beta-galactosidase activity" EXACT [EC:3.2.1.46] synonym: "cerebroside galactosidase activity" EXACT [EC:3.2.1.46] synonym: "D-galactosyl-N-acylsphingosine galactohydrolase activity" EXACT [EC:3.2.1.46] synonym: "galactocerebrosidase activity" EXACT [EC:3.2.1.46] synonym: "galactocerebroside beta-galactosidase activity" EXACT [EC:3.2.1.46] synonym: "galactocerebroside galactosidase activity" EXACT [EC:3.2.1.46] synonym: "galactocerebroside-beta-D-galactosidase activity" EXACT [EC:3.2.1.46] synonym: "galactocerebroside.beta-galactosidase activity" EXACT [EC:3.2.1.46] synonym: "galactosylceramidase I" RELATED [EC:3.2.1.46] synonym: "galactosylceramide beta-galactosidase activity" EXACT [EC:3.2.1.46] synonym: "galactosylceramide.beta-galactosidase activity" EXACT [EC:3.2.1.46] synonym: "galactosylcerebrosidase activity" EXACT [EC:3.2.1.46] synonym: "galcerase activity" EXACT [EC:3.2.1.46] synonym: "lactosylceramidase activity" EXACT [EC:3.2.1.46] synonym: "lactosylceramidase I" RELATED [EC:3.2.1.46] xref: EC:3.2.1.46 xref: GO:0004336 xref: MetaCyc:GALACTOSYLCERAMIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds is_a: CCO:F0003524 ! ceramidase activity [Term] id: CCO:F0000756 name: geranyltranstransferase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate." [EC:2.5.1.10] comment: Note that this is the second step in the formation of farnesyl diphosphate. The first step is 'dimethylallyltransferase activity ; GO:0004161'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'. subset: gosubset_prok synonym: "farnesyl diphosphate synthetase activity" EXACT [EC:2.5.1.10] synonym: "farnesyl pyrophosphate synthetase activity" EXACT [] synonym: "farnesyl-diphosphate synthase activity" EXACT [] synonym: "farnesylpyrophosphate synthetase activity" EXACT [EC:2.5.1.10] synonym: "FPP synthetase activity" EXACT [EC:2.5.1.10] synonym: "geranyl transferase I" RELATED [EC:2.5.1.10] synonym: "geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity" EXACT [EC:2.5.1.10] synonym: "geranyltransferase activity" EXACT [EC:2.5.1.10] xref: EC:2.5.1.10 xref: GO:0004337 xref: MetaCyc:FPPSYN-RXN is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0000757 name: glucan 1,3-beta-glucosidase activity namespace: molecular_function def: "Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of 1,3-beta-D-glucans, releasing alpha-glucose." [EC:3.2.1.58] synonym: "1,3-beta-glucan glucohydrolase activity" EXACT [EC:3.2.1.58] synonym: "beta-1,3-glucan exo-hydrolase activity" EXACT [EC:3.2.1.58] synonym: "exo (1->3)-beta-glucanase activity" EXACT [EC:3.2.1.58] synonym: "exo-1,3-beta-D-glucanase activity" EXACT [EC:3.2.1.58] synonym: "exo-1,3-beta-glucanase activity" EXACT [EC:3.2.1.58] synonym: "exo-1,3-beta-glucosidase activity" EXACT [EC:3.2.1.58] synonym: "exo-beta-(1->3)-D-glucanase activity" EXACT [EC:3.2.1.58] synonym: "exo-beta-(1->3)-glucanohydrolase activity" EXACT [EC:3.2.1.58] synonym: "exo-beta-1,3-D-glucanase activity" EXACT [EC:3.2.1.58] synonym: "exo-beta-1,3-glucanase activity" EXACT [EC:3.2.1.58] xref: EC:3.2.1.58 xref: GO:0004338 xref: MetaCyc:3.2.1.58-RXN is_a: CCO:F0001889 ! beta-glucosidase activity [Term] id: CCO:F0000758 name: glucan 1,4-alpha-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose." [EC:3.2.1.3] comment: Note that this term is not a child of 'alpha-glucosides activity ; GO:0004558', because in the reaction represented by GO:0004339 results in the release of beta-D-glucose, whereas in GO:0004558 alpha-D-glucose is released. subset: gosubset_prok synonym: "1,4-alpha-D-glucan glucohydrolase activity" EXACT [EC:3.2.1.3] synonym: "amyloglucosidase activity" EXACT [EC:3.2.1.3] synonym: "exo-1,4-alpha-glucosidase activity" EXACT [EC:3.2.1.3] synonym: "gamma-1,4-glucan glucohydrolase activity" EXACT [EC:3.2.1.3] synonym: "gamma-amylase activity" EXACT [EC:3.2.1.3] synonym: "glucoamylase activity" EXACT [] synonym: "glucose amylase activity" EXACT [EC:3.2.1.3] synonym: "lysosomal alpha-glucosidase activity" BROAD [EC:3.2.1.3] xref: EC:3.2.1.3 xref: GO:0004339 xref: MetaCyc:3.2.1.3-RXN is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0000759 name: glucokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose 6-phosphate." [EC:2.7.1.2] subset: gosubset_prok synonym: "ATP:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.2] synonym: "glucokinase (phosphorylating)" EXACT [EC:2.7.1.2] synonym: "glucose kinase activity" EXACT [EC:2.7.1.2] xref: EC:2.7.1.2 xref: GO:0004340 xref: MetaCyc:GLUCOKIN-RXN xref: Reactome:10457 is_a: CCO:F0000807 ! hexokinase activity [Term] id: CCO:F0000760 name: gluconolactonase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate." [EC:3.1.1.17] subset: gosubset_prok synonym: "aldonolactonase activity" EXACT [EC:3.1.1.17] synonym: "D-glucono-1,5-lactone lactonohydrolase activity" EXACT [EC:3.1.1.17] synonym: "glucono-delta-lactonase activity" EXACT [EC:3.1.1.17] synonym: "gulonolactonase activity" EXACT [EC:3.1.1.17] synonym: "lactonase activity" BROAD [EC:3.1.1.17] xref: EC:3.1.1.17 xref: GO:0004341 xref: MetaCyc:GLUCONOLACT-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0000761 name: glucosamine-6-phosphate deaminase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3." [EC:3.5.99.6] comment: Note that this function was formerly EC:5.3.1.10. subset: gosubset_prok synonym: "2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)" EXACT [EC:3.5.99.6] synonym: "aminodeoxyglucosephosphate isomerase activity" EXACT [EC:3.5.99.6] synonym: "GlcN6P deaminase activity" EXACT [EC:3.5.99.6] synonym: "glucosamine phosphate deaminase activity" EXACT [EC:3.5.99.6] synonym: "glucosamine-6-phosphate isomerase activity" EXACT [EC:3.5.99.6] synonym: "glucosaminephosphate isomerase" BROAD [EC:3.5.99.6] synonym: "phosphoglucosamine isomerase activity" EXACT [EC:3.5.99.6] synonym: "phosphoglucosaminisomerase activity" EXACT [EC:3.5.99.6] xref: EC:3.5.99.6 xref: GO:0004342 xref: MetaCyc:GLUCOSAMINE-6-P-DEAMIN-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0000762 name: glucosamine 6-phosphate N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + D-glucosamine 6-phosphate = CoA + N-acetyl-D-glucosamine 6-phosphate." [EC:2.3.1.4] subset: gosubset_prok synonym: "acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity" EXACT [EC:2.3.1.4] synonym: "aminodeoxyglucosephosphate acetyltransferase activity" EXACT [EC:2.3.1.4] synonym: "D-glucosamine-6-P N-acetyltransferase activity" EXACT [EC:2.3.1.4] synonym: "glucosamine 6-phosphate acetylase activity" EXACT [EC:2.3.1.4] synonym: "glucosamine-6-phosphate acetylase activity" EXACT [EC:2.3.1.4] synonym: "glucosamine-phosphate N-acetyltransferase activity" EXACT [] synonym: "N-acetylglucosamine-6-phosphate synthase activity" EXACT [EC:2.3.1.4] synonym: "phosphoglucosamine acetylase activity" EXACT [EC:2.3.1.4] synonym: "phosphoglucosamine N-acetylase activity" EXACT [EC:2.3.1.4] synonym: "phosphoglucosamine transacetylase activity" EXACT [EC:2.3.1.4] xref: EC:2.3.1.4 xref: GO:0004343 xref: MetaCyc:GLUCOSAMINEPNACETYLTRANS-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0000763 name: glucose dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor." [EC:1.1.99.10] synonym: "D-glucose:(acceptor) 1-oxidoreductase" EXACT [EC:1.1.99.10] synonym: "D-glucose:acceptor 1-oxidoreductase" EXACT [EC:1.1.5.2] synonym: "glucose dehydrogenase (acceptor) activity" EXACT [] synonym: "glucose dehydrogenase (Aspergillus) activity" NARROW [EC:1.1.99.10] synonym: "glucose dehydrogenase (decarboxylating)" EXACT [EC:1.1.99.10] xref: EC:1.1.-.- xref: EC:1.1.99.10 xref: GO:0004344 xref: GO:0008708 xref: MetaCyc:GLUCOSE-DEHYDROGENASE-(ACCEPTOR)-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0000764 name: glucose-6-phosphate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+." [EC:1.1.1.49] subset: gosubset_prok synonym: "6-phosphoglucose dehydrogenas" RELATED [] synonym: "6-phosphoglucose dehydrogenase activity" EXACT [] synonym: "D-glucose 6-phosphate dehydrogenase activity" EXACT [] synonym: "D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.49] synonym: "Entner-doudoroff enzyme" RELATED [EC:1.1.1.49] synonym: "G6PD activity" EXACT [EC:1.1.1.49] synonym: "G6PDH" EXACT [] synonym: "GDH" RELATED [] synonym: "glucose 6-phosphate dehydrogenase (NADP) activity" EXACT [] synonym: "glucose-6-phosphate 1-dehydrogenase activity" EXACT [] synonym: "NADP-dependent glucose 6-phosphate dehydrogenase activity" EXACT [] synonym: "NADP-glucose-6-phosphate dehydrogenase activity" EXACT [] synonym: "Zwischenferment" RELATED [] synonym: "zwischenferment" RELATED [EC:1.1.1.49] xref: EC:1.1.1.49 xref: GO:0004345 xref: MetaCyc:GLU6PDEHYDROG-RXN xref: Reactome:10468 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000765 name: glucose-6-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate." [EC:3.1.3.9] subset: gosubset_prok synonym: "D-glucose-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.9] synonym: "glucose 6-phosphate phosphatase activity" EXACT [EC:3.1.3.9] xref: EC:3.1.3.9 xref: GO:0004346 xref: MetaCyc:GLUCOSE-6-PHOSPHATASE-RXN xref: Reactome:10470 is_a: CCO:F0004126 ! carbohydrate phosphatase activity [Term] id: CCO:F0000766 name: glucose-6-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate." [EC:5.3.1.9] subset: gosubset_prok synonym: "D-glucose-6-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.9] synonym: "D-glucose-6-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.9] synonym: "glucose phosphate isomerase activity" EXACT [EC:5.3.1.9] synonym: "hexose monophosphate isomerase activity" BROAD [EC:5.3.1.9] synonym: "hexose phosphate isomerase activity" EXACT [EC:5.3.1.9] synonym: "hexosephosphate isomerase activity" BROAD [EC:5.3.1.9] synonym: "oxoisomerase activity" RELATED [EC:5.3.1.9] synonym: "phosphoglucoisomerase activity" EXACT [EC:5.3.1.9] synonym: "phosphoglucose isomerase activity" EXACT [EC:5.3.1.9] synonym: "phosphohexoisomerase activity" BROAD [EC:5.3.1.9] synonym: "phosphohexomutase activity" BROAD [EC:5.3.1.9] synonym: "phosphohexose isomerase activity" BROAD [EC:5.3.1.9] synonym: "phosphosaccharomutase activity" BROAD [EC:5.3.1.9] xref: EC:5.3.1.9 xref: GO:0004347 xref: MetaCyc:PGLUCISOM-RXN xref: Reactome:10472 is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0000767 name: glucosylceramidase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine." [EC:3.2.1.45] subset: gosubset_prok synonym: "acid beta-glucosidase activity" EXACT [EC:3.2.1.45] synonym: "beta-D-glucocerebrosidase activity" EXACT [EC:3.2.1.45] synonym: "beta-glucocerebrosidase activity" EXACT [EC:3.2.1.45] synonym: "beta-glucosylceramidase activity" EXACT [EC:3.2.1.45] synonym: "ceramide glucosidase activity" EXACT [EC:3.2.1.45] synonym: "D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [EC:3.2.1.45] synonym: "GlcCer-beta-glucosidase activity" EXACT [EC:3.2.1.45] synonym: "glucocerebrosidase activity" EXACT [EC:3.2.1.45] synonym: "glucosphingosine glucosylhydrolase activity" EXACT [EC:3.2.1.45] synonym: "glucosylcerebrosidase activity" EXACT [EC:3.2.1.45] synonym: "glucosylsphingosine beta-D-glucosidase activity" EXACT [EC:3.2.1.45] synonym: "glucosylsphingosine beta-glucosidase activity" EXACT [EC:3.2.1.45] synonym: "psychosine hydrolase activity" EXACT [EC:3.2.1.45] xref: EC:3.2.1.45 xref: GO:0004348 xref: MetaCyc:GLUCOSYLCERAMIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds is_a: CCO:F0003524 ! ceramidase activity [Term] id: CCO:F0000768 name: glutamate 5-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate = ADP + L-glutamate 5-phosphate." [EC:2.7.2.11] subset: gosubset_prok synonym: "ATP-L-glutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.11] synonym: "ATP:gamma-L-glutamate phosphotransferase activity" EXACT [EC:2.7.2.11] synonym: "ATP:L-glutamate 5-phosphotransferase activity" EXACT [EC:2.7.2.11] synonym: "gamma-glutamate kinase activity" EXACT [EC:2.7.2.11] synonym: "gamma-glutamyl kinase activity" EXACT [EC:2.7.2.11] synonym: "glutamate kinase activity" EXACT [EC:2.7.2.11] xref: EC:2.7.2.11 xref: GO:0004349 xref: MetaCyc:GLUTKIN-RXN is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor is_a: CCO:F0004125 ! amino acid kinase activity [Term] id: CCO:F0000769 name: glutamate-5-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate 5-semialdehyde + phosphate + NADP+ = L-gamma-glutamyl 5-phosphate + NADPH + H+." [EC:1.2.1.41] subset: gosubset_prok synonym: "beta-glutamylphosphate reductase activity" EXACT [EC:1.2.1.41] synonym: "gamma-glutamyl phosphate reductase activity" EXACT [EC:1.2.1.41] synonym: "gamma-glutamylphosphate reductase activity" EXACT [EC:1.2.1.41] synonym: "glutamate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.41] synonym: "glutamate-gamma-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.41] synonym: "glutamate-phosphate reductase activity" EXACT [] synonym: "glutamyl-gamma-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.41] synonym: "glutamylphosphate reductase activity" EXACT [] synonym: "L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.41] xref: EC:1.2.1.41 xref: GO:0001513 xref: GO:0004350 xref: MetaCyc:GLUTSEMIALDEHYDROG-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000770 name: glutamate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2." [EC:4.1.1.15] subset: gosubset_prok synonym: "aspartic alpha-decarboxylase" BROAD [EC:4.1.1.15] synonym: "cysteic acid decarboxylase activity" EXACT [EC:4.1.1.15] synonym: "gamma-glutamate decarboxylase activity" EXACT [EC:4.1.1.15] synonym: "L-aspartate-alpha-decarboxylase activity" EXACT [EC:4.1.1.15] synonym: "L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)" EXACT [EC:4.1.1.15] synonym: "L-glutamate 1-carboxy-lyase activity" EXACT [EC:4.1.1.15] synonym: "L-glutamate alpha-decarboxylase activity" EXACT [EC:4.1.1.15] synonym: "L-glutamic acid decarboxylase activity" EXACT [EC:4.1.1.15] synonym: "L-glutamic decarboxylase activity" EXACT [EC:4.1.1.15] xref: EC:4.1.1.15 xref: GO:0004351 xref: MetaCyc:GLUTDECARBOX-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000771 name: glutamate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+." [EC:1.4.1.2] subset: gosubset_prok synonym: "glutamate dehydrogenase (NAD)" EXACT [EC:1.4.1.2] synonym: "glutamate oxidoreductase activity" EXACT [EC:1.4.1.2] synonym: "glutamic acid dehydrogenase" BROAD [EC:1.4.1.2] synonym: "glutamic dehydrogenase activity" BROAD [EC:1.4.1.2] synonym: "L-glutamate dehydrogenase" BROAD [EC:1.4.1.2] synonym: "L-glutamate:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.2] synonym: "NAD-dependent glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] synonym: "NAD-dependent glutamic dehydrogenase activity" EXACT [EC:1.4.1.2] synonym: "NAD-glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] synonym: "NAD-linked glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] synonym: "NAD-linked glutamic dehydrogenase activity" EXACT [EC:1.4.1.2] synonym: "NAD-specific glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] synonym: "NAD-specific glutamic dehydrogenase activity" EXACT [EC:1.4.1.2] synonym: "NAD:glutamate oxidoreductase activity" EXACT [EC:1.4.1.2] synonym: "NADH-linked glutamate dehydrogenase activity" EXACT [EC:1.4.1.2] xref: EC:1.4.1.2 xref: GO:0004352 xref: MetaCyc:GLUTAMATE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000772 name: glutamate dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+." [EC:1.4.1.3] comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step. subset: gosubset_prok synonym: "glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)" RELATED [] synonym: "glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)" RELATED [] synonym: "glutamic dehydrogenase activity" BROAD [EC:1.4.1.3] synonym: "L-glutamate:NAD(P)+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.3] xref: EC:1.4.1.3 xref: GO:0004353 xref: MetaCyc:GLUTAMATE-DEHYDROGENASE-(NAD(P)+)-RXN xref: MetaCyc:GLUTAMATE-SYN2-PWY xref: Reactome:10485 is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000773 name: glutamate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+." [EC:1.4.1.4] subset: gosubset_prok synonym: "dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))" EXACT [EC:1.4.1.4] synonym: "glutamic acid dehydrogenase" BROAD [EC:1.4.1.4] synonym: "glutamic dehydrogenase activity" BROAD [EC:1.4.1.4] synonym: "L-glutamate dehydrogenase" BROAD [EC:1.4.1.4] synonym: "L-glutamate:NADP+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.4] synonym: "L-glutamic acid dehydrogenase activity" EXACT [EC:1.4.1.4] synonym: "NAD(P)-glutamate dehydrogenase activity" EXACT [EC:1.4.1.4] synonym: "NAD(P)H-dependent glutamate dehydrogenase activity" EXACT [EC:1.4.1.4] xref: EC:1.4.1.4 xref: GO:0004354 xref: MetaCyc:GLUTDEHYD-RXN xref: MetaCyc:GLUTSYNIII-PWY is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000774 name: glutamate synthase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+." [EC:1.4.1.13] comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step. subset: gosubset_prok synonym: "glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity" EXACT [EC:1.4.1.13] synonym: "glutamate synthetase (NADP) activity" EXACT [EC:1.4.1.13] synonym: "glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity" EXACT [EC:1.4.1.13] synonym: "glutamine-ketoglutaric aminotransferase activity" EXACT [EC:1.4.1.13] synonym: "GOGAT activity" EXACT [EC:1.4.1.13] synonym: "L-glutamate synthase activity" BROAD [EC:1.4.1.13] synonym: "L-glutamate synthetase activity" BROAD [EC:1.4.1.13] synonym: "L-glutamate:NADP+ oxidoreductase (transaminating)" EXACT [EC:1.4.1.13] synonym: "L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity" EXACT [EC:1.4.1.13] synonym: "NADPH-dependent glutamate synthase activity" EXACT [EC:1.4.1.13] synonym: "NADPH-glutamate synthase activity" EXACT [EC:1.4.1.13] synonym: "NADPH-linked glutamate synthase" EXACT [EC:1.4.1.13] xref: EC:1.4.1.13 xref: GO:0004355 xref: MetaCyc:GLUGLNSYN-PWY xref: MetaCyc:GLUTAMATESYN-RXN xref: MetaCyc:GLUTSYN-PWY is_a: CCO:F0006093 ! glutamate synthase activity, NADH or NADPH as acceptor [Term] id: CCO:F0000775 name: glutamate-ammonia ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine." [EC:6.3.1.2] subset: gosubset_prok synonym: "glutamine synthetase activity" EXACT [] synonym: "glutamylhydroxamic synthetase activity" EXACT [EC:6.3.1.2] synonym: "L-glutamate:ammonia ligase (ADP-forming)" EXACT [EC:6.3.1.2] synonym: "L-glutamine synthetase activity" EXACT [EC:6.3.1.2] xref: EC:6.3.1.2 xref: GO:0004356 xref: MetaCyc:GLUTAMINESYN-RXN xref: Reactome:10495 is_a: CCO:F0003071 ! ammonia ligase activity [Term] id: CCO:F0000776 name: glutamate-cysteine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L-cysteine." [EC:6.3.2.2] subset: gosubset_prok synonym: "gamma-glutamyl-L-cysteine synthetase activity" EXACT [EC:6.3.2.2] synonym: "gamma-glutamylcysteine synthetase activity" EXACT [EC:6.3.2.2] synonym: "gamma-glutamylcysteinyl synthetase activity" EXACT [EC:6.3.2.2] synonym: "L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity" EXACT [EC:6.3.2.2] xref: EC:6.3.2.2 xref: GO:0004357 xref: MetaCyc:GLUTCYSLIG-RXN xref: Reactome:10497 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0000777 name: glutamate N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N2-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate." [EC:2.3.1.35] subset: gosubset_prok synonym: "2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity" EXACT [EC:2.3.1.35] synonym: "acetylglutamate synthetase activity" EXACT [EC:2.3.1.35] synonym: "acetylglutamate-acetylornithine transacetylase activity" EXACT [EC:2.3.1.35] synonym: "acetylglutamic synthetase activity" EXACT [EC:2.3.1.35] synonym: "acetylglutamic-acetylornithine transacetylase activity" EXACT [EC:2.3.1.35] synonym: "acetylornithinase activity" BROAD [EC:2.3.1.35] synonym: "acetylornithine glutamate acetyltransferase activity" EXACT [EC:2.3.1.35] synonym: "alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity" EXACT [EC:2.3.1.35] synonym: "glutamate acetyltransferase activity" EXACT [EC:2.3.1.35] synonym: "N-acetyl-L-glutamate synthetase activity" BROAD [EC:2.3.1.35] synonym: "N-acetylglutamate synthase activity" BROAD [EC:2.3.1.35] synonym: "N-acetylglutamate synthetase activity" BROAD [EC:2.3.1.35] synonym: "N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity" EXACT [EC:2.3.1.35] synonym: "ornithine acetyltransferase activity" EXACT [EC:2.3.1.35] synonym: "ornithine transacetylase activity" EXACT [EC:2.3.1.35] xref: EC:2.3.1.35 xref: GO:0004358 xref: MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0000778 name: glutaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3." [EC:3.5.1.2] subset: gosubset_prok synonym: "glutaminase I" RELATED [EC:3.5.1.2] synonym: "glutamine aminohydrolase activity" EXACT [EC:3.5.1.2] synonym: "L-glutaminase activity" EXACT [EC:3.5.1.2] synonym: "L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.2] xref: EC:3.5.1.2 xref: GO:0004359 xref: MetaCyc:GLUTAMIN-RXN xref: Reactome:10219 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000779 name: glutamine-fructose-6-phosphate transaminase (isomerizing) activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate." [EC:2.6.1.16] subset: gosubset_prok synonym: "D-fructose-6-phosphate amidotransferase activity" EXACT [EC:2.6.1.16] synonym: "GlcN6P synthase activity" EXACT [EC:2.6.1.16] synonym: "glucosamine 6-phosphate synthase activity" EXACT [EC:2.6.1.16] synonym: "glucosamine--fructose-6-phosphate aminotransferase (isomerizing) activity" EXACT [EC:2.6.1.16] synonym: "glucosamine-6-phosphate isomerase (glutamine-forming) activity" EXACT [] synonym: "glucosamine-6-phosphate synthase activity" EXACT [EC:2.6.1.16] synonym: "glucosaminephosphate isomerase" BROAD [EC:2.6.1.16] synonym: "hexosephosphate aminotransferase activity" EXACT [EC:2.6.1.16] synonym: "L-glutamine-D-fructose-6-phosphate amidotransferase activity" EXACT [EC:2.6.1.16] synonym: "L-glutamine:D-fructose-6-phosphate isomerase (deaminating)" EXACT [EC:2.6.1.16] xref: EC:2.6.1.16 xref: GO:0004360 xref: MetaCyc:L-GLN-FRUCT-6-P-AMINOTRANS-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000780 name: glutaryl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor." [EC:1.3.99.7] subset: gosubset_prok synonym: "glutaryl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.7] synonym: "glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating)" EXACT [EC:1.3.99.7] synonym: "glutaryl-CoA:acceptor 2,3-oxidoreductase (decarboxylating)" EXACT [EC:1.3.99.7] xref: EC:1.3.99.7 xref: GO:0004361 xref: MetaCyc:GLUTARYL-COA-DEHYDROGENASE-RXN xref: Reactome:10507 xref: UM-BBD_enzymeID:e0123 is_a: CCO:F0000480 ! acyl-CoA dehydrogenase activity [Term] id: CCO:F0000781 name: glutathione-disulfide reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+." [EC:1.8.1.7, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this function was formerly EC:1.6.4.2. subset: gosubset_prok synonym: "glutathione reductase (NADPH) activity" EXACT [] synonym: "glutathione reductase activity" EXACT [] synonym: "glutathione S-reductase activity" EXACT [EC:1.8.1.7] synonym: "glutathione-disulphide reductase activity" EXACT [] synonym: "glutathione:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.7] synonym: "GSH reductase activity" EXACT [EC:1.8.1.7] synonym: "GSSG reductase activity" EXACT [EC:1.8.1.7] synonym: "NADPH-glutathione reductase activity" EXACT [EC:1.8.1.7] synonym: "NADPH-GSSG reductase activity" EXACT [EC:1.8.1.7] synonym: "NADPH:oxidized-glutathione oxidoreductase activity" EXACT [EC:1.8.1.7] synonym: "oxidized glutathione reduction" RELATED [] xref: EC:1.8.1.7 xref: GO:0004362 xref: MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN xref: Reactome:10508 is_a: CCO:F0002535 ! glutathione disulfide oxidoreductase activity is_a: CCO:F0003069 ! antioxidant activity is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000782 name: glutathione synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione." [EC:6.3.2.3] subset: gosubset_prok synonym: "gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)" EXACT [EC:6.3.2.3] synonym: "glutathione synthetase activity" EXACT [EC:6.3.2.3] synonym: "GSH synthetase activity" EXACT [EC:6.3.2.3] xref: EC:6.3.2.3 xref: GO:0004363 xref: MetaCyc:GLUTATHIONE-SYN-RXN xref: Reactome:10524 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0000783 name: glutathione transferase activity namespace: molecular_function def: "Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group." [EC:2.5.1.18] subset: gosubset_prok synonym: "glutathione conjugation reaction" EXACT [] synonym: "glutathione S-alkyl transferase activity" EXACT [EC:2.5.1.18] synonym: "glutathione S-alkyltransferase activity" EXACT [EC:2.5.1.18] synonym: "glutathione S-aralkyltransferase activity" EXACT [EC:2.5.1.18] synonym: "glutathione S-aryltransferase activity" EXACT [EC:2.5.1.18] synonym: "glutathione S-transferase activity" EXACT [EC:2.5.1.18] synonym: "RX:glutathione R-transferase activity" EXACT [EC:2.5.1.18] synonym: "S-(hydroxyalkyl)glutathione lyase activity" EXACT [EC:2.5.1.18] xref: EC:2.5.1.18 xref: GO:0004364 xref: MetaCyc:GSHTRAN-RXN xref: Reactome:10527 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000784 name: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+." [EC:1.2.1.12] subset: gosubset_prok synonym: "3-phosphoglyceraldehyde dehydrogenase activity" EXACT [EC:1.2.1.12] synonym: "D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.12] synonym: "dehydrogenase, glyceraldehyde phosphate" EXACT [EC:1.2.1.12] synonym: "GAPDH activity" EXACT [EC:1.2.1.12] synonym: "glyceraldehyde phosphate dehydrogenase (NAD)" EXACT [EC:1.2.1.12] synonym: "glyceraldehyde-3-P-dehydrogenase activity" EXACT [EC:1.2.1.12] synonym: "NAD-dependent glyceraldehyde phosphate dehydrogenase activity" EXACT [EC:1.2.1.12] synonym: "NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [EC:1.2.1.12] synonym: "NADH-glyceraldehyde phosphate dehydrogenase activity" EXACT [EC:1.2.1.12] synonym: "phosphoglyceraldehyde dehydrogenase activity" EXACT [EC:1.2.1.12] synonym: "triosephosphate dehydrogenase activity" BROAD [EC:1.2.1.12] xref: EC:1.2.1.12 xref: GO:0004365 xref: MetaCyc:GAPOXNPHOSPHN-RXN xref: Reactome:10530 is_a: CCO:F0002279 ! glyceraldehyde-3-phosphate dehydrogenase activity [Term] id: CCO:F0000785 name: glycerol-3-phosphate O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate." [EC:2.3.1.15] subset: gosubset_prok synonym: "3-glycerophosphate acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "ACP:sn-glycerol-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "alpha-glycerophosphate acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "glycerol 3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "glycerol phosphate acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "glycerol phosphate transacylase activity" EXACT [EC:2.3.1.15] synonym: "glycerophosphate acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "glycerophosphate transacylase activity" EXACT [EC:2.3.1.15] synonym: "sn-glycerol 3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] synonym: "sn-glycerol-3-phosphate acyltransferase activity" EXACT [EC:2.3.1.15] xref: EC:2.3.1.15 xref: GO:0004366 xref: MetaCyc:RXN-1381 xref: Reactome:10531 is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0000786 name: glycerol-3-phosphate dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+." [EC:1.1.1.8] subset: gosubset_prok synonym: "alpha-glycerol phosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] synonym: "alpha-glycerophosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] synonym: "glycerol 1-phosphate dehydrogenase activity" RELATED [EC:1.1.1.8] synonym: "glycerol phosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] synonym: "glycerol-3-phosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] synonym: "glycerophosphate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.8] synonym: "hydroglycerophosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "L-alpha-glycerol phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "L-alpha-glycerophosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "L-glycerol phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "L-glycerophosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "NAD-alpha-glycerophosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "NAD-dependent glycerol phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "NAD-dependent glycerol-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "NAD-L-glycerol-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "NAD-linked glycerol 3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.8] synonym: "NADH-dihydroxyacetone phosphate reductase activity" RELATED [EC:1.1.1.8] xref: EC:1.1.1.8 xref: GO:0004367 xref: MetaCyc:1.1.1.8-RXN xref: Reactome:10533 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000787 name: glycerol-3-phosphate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor." [EC:1.1.99.5] subset: gosubset_prok synonym: "alpha-glycerophosphate dehydrogenase" EXACT [EC:1.1.99.5] synonym: "alpha-glycerophosphate dehydrogenase (acceptor)" EXACT [EC:1.1.99.5] synonym: "dehydrogenase, glycerol phosphate (acceptor)" EXACT [EC:1.1.99.5] synonym: "DL-glycerol 3-phosphate oxidase" EXACT [EC:1.1.99.5] synonym: "FAD-dependent glycerol-3-phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "FAD-dependent sn-glycerol-3-phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "FAD-linked glycerol 3-phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "FAD-linked L-glycerol-3-phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "flavin-linked glycerol-3-phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "flavoprotein-linked L-glycerol 3-phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "glycerol 3-phosphate cytochrome c reductase" NARROW [EC:1.1.99.5] synonym: "glycerol phosphate dehydrogenase" EXACT [EC:1.1.99.5] synonym: "glycerol phosphate dehydrogenase (acceptor)" EXACT [EC:1.1.99.5] synonym: "glycerol phosphate dehydrogenase (FAD)" NARROW [EC:1.1.99.5] synonym: "glycerol-3-phosphate dehydrogenase (flavin-linked)" NARROW [EC:1.1.99.5] synonym: "glycerophosphate dehydrogenase" EXACT [EC:1.1.99.5] synonym: "L-3-glycerophosphate-ubiquinone oxidoreductase" EXACT [EC:1.1.99.5] synonym: "L-glycerol-3-phosphate dehydrogenase" EXACT [EC:1.1.99.5] synonym: "NAD-independent glycerol phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "pyridine nucleotide-independent L-glycerol 3-phosphate dehydrogenase" NARROW [EC:1.1.99.5] synonym: "sn-glycerol 3-phosphate oxidase" EXACT [EC:1.1.99.5] synonym: "sn-glycerol-3-phosphate dehydrogenase" EXACT [EC:1.1.99.5] synonym: "sn-glycerol-3-phosphate:(acceptor) 2-oxidoreductase" EXACT [EC:1.1.99.5] synonym: "sn-glycerol-3-phosphate:acceptor 2-oxidoreductase" EXACT [EC:1.1.99.5] xref: EC:1.1.99.5 xref: GO:0004368 xref: MetaCyc:GLYCEROL-3-PHOSPHATE-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0000788 name: glycerol-3-phosphate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: sn-glycerol 3-phosphate + O2 = glycerone phosphate + H2O2." [EC:1.1.3.21] subset: gosubset_prok synonym: "alpha-glycerophosphate oxidase activity" EXACT [EC:1.1.3.21] synonym: "glycerol phosphate oxidase activity" EXACT [EC:1.1.3.21] synonym: "glycerol-1-phosphate oxidase activity" EXACT [EC:1.1.3.21] synonym: "L-alpha-glycerol-3-phosphate oxidase activity" EXACT [EC:1.1.3.21] synonym: "L-alpha-glycerophosphate oxidase activity" EXACT [EC:1.1.3.21] synonym: "sn-glycerol-3-phosphate:oxygen 2-oxidoreductase activity" EXACT [EC:1.1.3.21] xref: EC:1.1.3.21 xref: GO:0004369 xref: MetaCyc:GLYCEROL-3-PHOSPHATE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0000789 name: glycerol kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + glycerol = ADP + glycerol 3-phosphate." [EC:2.7.1.30] subset: gosubset_prok synonym: "ATP:glycerol 3-phosphotransferase activity" EXACT [EC:2.7.1.30] synonym: "ATP:glycerol-3-phosphotransferase activity" EXACT [EC:2.7.1.30] synonym: "GK" RELATED [EC:2.7.1.30] synonym: "glyceric kinase activity" EXACT [EC:2.7.1.30] synonym: "glycerokinase activity" EXACT [EC:2.7.1.30] synonym: "glycerol kinase (phosphorylating)" EXACT [EC:2.7.1.30] xref: EC:2.7.1.30 xref: GO:0004370 xref: MetaCyc:GLYCEROL-KIN-RXN xref: Reactome:10545 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000790 name: glycerone kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate." [EC:2.7.1.29] subset: gosubset_prok synonym: "acetol kinase (phosphorylating)" EXACT [EC:2.7.1.29] synonym: "acetol kinase activity" EXACT [EC:2.7.1.29] synonym: "ATP:glycerone phosphotransferase activity" EXACT [EC:2.7.1.29] synonym: "dihydroxyacetone kinase activity" EXACT [EC:2.7.1.29] xref: EC:2.7.1.29 xref: GO:0004371 xref: MetaCyc:GLYCERONE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000791 name: glycine hydroxymethyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine." [EC:2.1.2.1] subset: gosubset_prok synonym: "5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1] synonym: "allothreonine aldolase activity" EXACT [EC:2.1.2.1] synonym: "L-serine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1] synonym: "serine aldolase activity" EXACT [EC:2.1.2.1] synonym: "serine hydroxymethylase activity" EXACT [EC:2.1.2.1] synonym: "serine hydroxymethyltransferase activity" EXACT [EC:2.1.2.1] synonym: "serine transhydroxymethylase activity" EXACT [EC:2.1.2.1] xref: EC:2.1.2.1 xref: GO:0004372 xref: MetaCyc:GLYOHMETRANS-RXN xref: Reactome:1060 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0000792 name: glycogen (starch) synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1)." [EC:2.4.1.11] subset: gosubset_prok synonym: "glycogen (starch) synthetase activity" EXACT [EC:2.4.1.11] synonym: "UDP-glucose-glycogen glucosyltransferase activity" EXACT [EC:2.4.1.11] synonym: "UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.11] synonym: "UDP-glycogen synthase activity" EXACT [EC:2.4.1.11] synonym: "UDPG-glycogen synthetase activity" EXACT [EC:2.4.1.11] synonym: "UDPG-glycogen transglucosylase activity" EXACT [EC:2.4.1.11] synonym: "UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.11] synonym: "uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [EC:2.4.1.11] xref: EC:2.4.1.11 xref: GO:0004373 xref: MetaCyc:GLYCOGEN-(STARCH)-SYNTHASE-RXN xref: Reactome:10552 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0000793 name: glycine dehydrogenase (decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2." [EC:1.4.4.2] subset: gosubset_prok synonym: "glycine cleavage system P-protein activity" NARROW [EC:1.4.4.2] synonym: "glycine decarboxylase activity" EXACT [EC:1.4.4.2] synonym: "glycine-cleavage complex" RELATED [EC:1.4.4.2] synonym: "glycine-cleavage complex P-protein activity" EXACT [EC:1.4.4.2] synonym: "glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)" EXACT [EC:1.4.4.2] synonym: "glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)" EXACT [EC:1.4.4.2] synonym: "P-protein" NARROW [EC:1.4.4.2] synonym: "protein P1" NARROW [EC:1.4.4.2] xref: EC:1.4.4.2 xref: GO:0004375 xref: MetaCyc:GCVP-RXN is_a: CCO:F0003242 ! oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor [Term] id: CCO:F0000794 name: glycolipid mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage." [GOC:ai] synonym: "glycolipid mannosyl transferase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0004376 xref: GO:0004580 xref: Reactome:10559 is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000795 name: glycolipid 2-alpha-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,2-D-mannosyl-D-mannose linkage." [EC:2.4.1.131] synonym: "GDP-mannose-oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.131] synonym: "GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.131] synonym: "guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.131] synonym: "oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.131] xref: EC:2.4.1.131 xref: GO:0004377 xref: MetaCyc:2.4.1.131-RXN is_a: CCO:F0000007 ! alpha-1,2-mannosyltransferase activity is_a: CCO:F0000794 ! glycolipid mannosyltransferase activity [Term] id: CCO:F0000796 name: glycolipid 3-alpha-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,3-D-mannosyl-D-mannose linkage." [EC:2.4.1.132] synonym: "GDP-mannose-oligosaccharide-lipid mannosyltransferase II" RELATED [EC:2.4.1.132] synonym: "GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.132] synonym: "guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity" EXACT [EC:2.4.1.132] synonym: "mannosyltransferase II activity" EXACT [EC:2.4.1.132] xref: EC:2.4.1.132 xref: GO:0004378 xref: MetaCyc:2.4.1.132-RXN is_a: CCO:F0000794 ! glycolipid mannosyltransferase activity [Term] id: CCO:F0000797 name: glycylpeptide N-tetradecanoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide." [EC:2.3.1.97] synonym: "myristoyl-CoA-protein N-myristoyltransferase activity" EXACT [EC:2.3.1.97] synonym: "myristoyl-coenzyme A:protein N-myristoyl transferase activity" EXACT [EC:2.3.1.97] synonym: "myristoylating enzymes" RELATED [EC:2.3.1.97] synonym: "N-myristoyltransferase activity" EXACT [] synonym: "peptide N-myristoyltransferase activity" EXACT [EC:2.3.1.97] synonym: "peptide N-tetradecanoyltransferase activity" EXACT [EC:2.3.1.97] synonym: "protein N-myristoyltransferase activity" EXACT [EC:2.3.1.97] synonym: "tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase activity" EXACT [EC:2.3.1.97] xref: EC:2.3.1.97 xref: GO:0004379 xref: GO:0019106 xref: MetaCyc:2.3.1.97-RXN is_a: CCO:F0003133 ! N-acyltransferase activity is_a: CCO:F0004053 ! myristoyltransferase activity [Term] id: CCO:F0000798 name: glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose." [EC:2.4.1.40] synonym: "A transferase activity" RELATED [EC:2.4.1.40] synonym: "A-transferase activity" EXACT [EC:2.4.1.40] synonym: "alpha-3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] synonym: "blood-group substance A-dependent acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] synonym: "blood-group substance alpha-acetyltransferase activity" EXACT [EC:2.4.1.40] synonym: "fucosylgalactose acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] synonym: "fucosylgalactose alpha-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] synonym: "fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] synonym: "histo-blood group A acetylgalactosaminyltransferase activity" NARROW [EC:2.4.1.40] synonym: "histo-blood group A glycosyltransferase (Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase)" EXACT [EC:2.4.1.40] synonym: "histo-blood group A transferase activity" RELATED [EC:2.4.1.40] synonym: "UDP-GalNAc:Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.40] synonym: "UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.40] synonym: "UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.40] xref: EC:2.4.1.40 xref: GO:0004380 xref: MetaCyc:2.4.1.40-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0000799 name: fucosylgalactoside 3-alpha-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose." [EC:2.4.1.37] synonym: "[blood group substance] alpha-galactosyltransferase activity" NARROW [EC:2.4.1.37] synonym: "B transferase activity" RELATED [EC:2.4.1.37] synonym: "blood-group substance B-dependent galactosyltransferase activity" NARROW [EC:2.4.1.37] synonym: "blood-group substance beta-dependent galactosyltransferase activity" NARROW [EC:2.4.1.37] synonym: "fucosylglycoprotein 3-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.37] synonym: "glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity" EXACT [] synonym: "histo-blood group B transferase activity" NARROW [EC:2.4.1.37] synonym: "histo-blood substance B-dependent galactosyltransferase activity" EXACT [EC:2.4.1.37] synonym: "histo-blood substance beta-dependent galactosyltransferase activity" NARROW [EC:2.4.1.37] synonym: "UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] synonym: "UDPgalactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] synonym: "UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] synonym: "UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] xref: EC:2.4.1.37 xref: GO:0004381 xref: MetaCyc:2.4.1.37-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0000800 name: guanosine-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: GDP + H2O = GMP + phosphate." [EC:3.6.1.42, PMID:2989286] synonym: "GDP phosphohydrolase activity" EXACT [EC:3.6.1.42] synonym: "GDPase activity" EXACT [EC:3.6.1.42] synonym: "guanosine 5'-diphosphatase activity" EXACT [EC:3.6.1.6] synonym: "guanosine diphosphatase activity" EXACT [] xref: EC:3.6.1.42 xref: GO:0004382 xref: MetaCyc:GUANOSINE-DIPHOSPHATASE-RXN is_a: CCO:F0003573 ! nucleoside-diphosphatase activity [Term] id: CCO:F0000801 name: guanylate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate." [EC:4.6.1.2] subset: gosubset_prok synonym: "GTP diphosphate-lyase (cyclizing) activity" EXACT [EC:4.6.1.2] synonym: "GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity" EXACT [EC:4.6.1.2] synonym: "guanyl cyclase activity" EXACT [EC:4.6.1.2] synonym: "guanylyl cyclase activity" EXACT [] synonym: "receptor guanylate cyclase activity" NARROW [] xref: EC:4.6.1.2 xref: GO:0004383 xref: MetaCyc:GUANYLCYC-RXN is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0000802 name: guanylate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + GMP = ADP + GDP." [EC:2.7.4.8] subset: gosubset_prok synonym: "5'-GMP kinase activity" EXACT [EC:2.7.4.8] synonym: "ATP:(d)GMP phosphotransferase activity" EXACT [EC:2.7.4.8] synonym: "ATP:GMP phosphotransferase activity" EXACT [EC:2.7.4.8] synonym: "deoxyguanylate kinase activity" RELATED [EC:2.7.4.8] synonym: "GMP kinase activity" EXACT [EC:2.7.4.8] synonym: "guanosine monophosphate kinase activity" EXACT [EC:2.7.4.8] synonym: "membrane-associated guanylate kinase" NARROW [] xref: EC:2.7.4.8 xref: GO:0004385 xref: MetaCyc:GUANYL-KIN-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004124 ! nucleotide kinase activity [Term] id: CCO:F0000803 name: helicase activity namespace: molecular_function def: "Catalysis of the unwinding of a DNA or RNA duplex." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that most helicases catalyze processive duplex unwinding. subset: goslim_candida subset: goslim_goa subset: goslim_pir subset: goslim_yeast subset: gosubset_prok xref: GO:0004386 xref: Reactome:7001 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0000804 name: heme oxygenase (decyclizing) activity namespace: molecular_function def: "Catalysis of the reaction: heme + 3 donor-H2 + 3 O2 = biliverdin + Fe2+ + CO + 3 acceptor + 3 H2O." [EC:1.14.99.3] synonym: "haem oxidase activity" EXACT [EC:1.14.99.3] synonym: "haem oxygenase (decyclizing) activity" EXACT [] synonym: "haem oxygenase activity" EXACT [EC:1.14.99.3] synonym: "heme oxidase activity" EXACT [EC:1.14.99.3] synonym: "heme oxygenase activity" EXACT [EC:1.14.99.3] synonym: "heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)" EXACT [EC:1.14.99.3] synonym: "ORP33 proteins" RELATED [EC:1.14.99.3] xref: EC:1.14.99.3 xref: GO:0004392 xref: MetaCyc:HEME-OXYGENASE-(DECYCLIZING)-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0000805 name: heparan sulfate 2-O-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate." [PMID:9153262] synonym: "heparan-sulfate 2-O-sulphotransferase activity" EXACT [] synonym: "heparin 2-sulfotransferase activity" RELATED [] synonym: "heparin-sulphate 2-sulphotransferase activity" RELATED [] xref: EC:2.8.2.- xref: GO:0004394 is_a: CCO:F0008398 ! heparan sulfate sulfotransferase activity [Term] id: CCO:F0000806 name: hexaprenyldihydroxybenzoate methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate." [EC:2.1.1.114] synonym: "3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase activity" EXACT [EC:2.1.1.114] synonym: "DHHB methyltransferase activity" EXACT [EC:2.1.1.114] synonym: "DHHB-Mt activity" EXACT [EC:2.1.1.114] synonym: "dihydroxyhexaprenylbenzoate methyltransferase activity" EXACT [EC:2.1.1.114] synonym: "S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase activity" EXACT [EC:2.1.1.114] xref: EC:2.1.1.114 xref: GO:0004395 xref: MetaCyc:2.1.1.114-RXN is_a: CCO:F0002494 ! polyprenyldihydroxybenzoate methyltransferase activity [Term] id: CCO:F0000807 name: hexokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate." [EC:2.7.1.1] subset: gosubset_prok synonym: "ATP-dependent hexokinase activity" EXACT [EC:2.7.1.1] synonym: "ATP:D-hexose 6-phosphotransferase activity" EXACT [EC:2.7.1.1] synonym: "glucose ATP phosphotransferase activity" EXACT [EC:2.7.1.1] synonym: "hexokinase (phosphorylating)" EXACT [EC:2.7.1.1] synonym: "hexokinase D" RELATED [EC:2.7.1.1] synonym: "hexokinase type I activity" NARROW [EC:2.7.1.1] synonym: "hexokinase type II activity" NARROW [EC:2.7.1.1] synonym: "hexokinase type III activity" NARROW [EC:2.7.1.1] synonym: "hexokinase type IV" RELATED [EC:2.7.1.1] synonym: "hexokinase type IV (glucokinase) activity" NARROW [EC:2.7.1.1] synonym: "hexokinase type IV glucokinase activity" EXACT [EC:2.7.1.1] xref: EC:2.7.1.1 xref: GO:0004396 xref: MetaCyc:HEXOKINASE-RXN xref: Reactome:10602 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0000808 name: histidine ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-histidine = urocanate + NH3." [EC:4.3.1.3] subset: gosubset_prok synonym: "histidase activity" RELATED [GOC:hjd] synonym: "histidinase activity" RELATED [GOC:hjd] synonym: "histidine alpha-deaminase activity" RELATED [GOC:hjd] synonym: "L-histidine ammonia-lyase (urocanate-forming)" EXACT [EC:4.3.1.3] synonym: "L-histidine ammonia-lyase activity" EXACT [EC:4.3.1.3] xref: EC:4.3.1.3 xref: GO:0004397 xref: MetaCyc:HISTIDINE-AMMONIA-LYASE-RXN xref: Reactome:10604 is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0000809 name: histidine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-histidine = histamine + CO2." [EC:4.1.1.22] subset: gosubset_prok synonym: "L-histidine carboxy-lyase (histamine-forming)" EXACT [EC:4.1.1.22] synonym: "L-histidine carboxy-lyase activity" EXACT [EC:4.1.1.22] synonym: "L-histidine decarboxylase activity" EXACT [EC:4.1.1.22] xref: EC:4.1.1.22 xref: GO:0004398 xref: MetaCyc:HISTIDINE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000810 name: histidinol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+." [EC:1.1.1.23] subset: gosubset_prok xref: EC:1.1.1.23 xref: GO:0004399 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000811 name: histidinol-phosphate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate." [EC:2.6.1.9] subset: gosubset_prok synonym: "glutamic-imidazoleacetol phosphate transaminase activity" EXACT [EC:2.6.1.9] synonym: "histidine:imidazoleacetol phosphate transaminase activity" EXACT [EC:2.6.1.9] synonym: "histidinol phosphate aminotransferase activity" EXACT [EC:2.6.1.9] synonym: "histidinol-phosphate aminotransferase activity" EXACT [] synonym: "IAP transaminase activity" EXACT [EC:2.6.1.9] synonym: "imidazole acetol-phosphate transaminase activity" EXACT [EC:2.6.1.9] synonym: "imidazoleacetol phosphate transaminase activity" EXACT [EC:2.6.1.9] synonym: "imidazolylacetolphosphate aminotransferase activity" EXACT [EC:2.6.1.9] synonym: "imidazolylacetolphosphate transaminase activity" EXACT [EC:2.6.1.9] synonym: "L-histidinol phosphate aminotransferase activity" EXACT [EC:2.6.1.9] synonym: "L-histidinol-phosphate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.9] xref: EC:2.6.1.9 xref: GO:0004400 xref: MetaCyc:HISTAMINOTRANS-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000812 name: histidinol-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: L-histidinol-phosphate + H2O = L-histidinol + phosphate." [EC:3.1.3.15] subset: gosubset_prok synonym: "histidinol phosphate phosphatase activity" EXACT [EC:3.1.3.15] synonym: "histidinolphosphatase activity" EXACT [EC:3.1.3.15] synonym: "histidinolphosphate phosphatase activity" EXACT [EC:3.1.3.15] synonym: "HPpase activity" EXACT [EC:3.1.3.15] synonym: "L-histidinol phosphate phosphatase activity" EXACT [EC:3.1.3.15] synonym: "L-histidinol-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.15] xref: EC:3.1.3.15 xref: GO:0004401 xref: MetaCyc:HISTIDPHOS-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000813 name: histone acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone." [EC:2.3.1.48] comment: Note that the term 'histone lysine acetyltransferase activity ; GO:0046971' was merged into this term because only lysine residues are ever acetylated in histones, and so the term was redundant. synonym: "acetyl-CoA:histone acetyltransferase activity" EXACT [EC:2.3.1.48] synonym: "histone acetokinase activity" EXACT [EC:2.3.1.48] synonym: "histone acetylase activity" EXACT [] synonym: "histone lysine acetyltransferase activity" EXACT [] synonym: "histone transacetylase activity" EXACT [EC:2.3.1.48] synonym: "nucleosome-histone acetyltransferase activity" EXACT [EC:2.3.1.48] xref: EC:2.3.1.48 xref: GO:0004402 xref: GO:0004403 xref: GO:0004404 xref: GO:0046971 xref: MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN is_a: CCO:F0000868 ! lysine N-acetyltransferase activity [Term] id: CCO:F0000814 name: H2A/H2B histone acetyltransferase activity namespace: molecular_function def: "Catalysis of the addition of an acetyl group to a histone, specific for histones H2A and H2B." [GOC:jl, PMID:9241414] xref: EC:2.3.1.- xref: GO:0004405 is_a: CCO:F0000813 ! histone acetyltransferase activity [Term] id: CCO:F0000815 name: H3/H4 histone acetyltransferase activity namespace: molecular_function def: "Catalysis of the addition of an acetyl group to a histone, specific for histones H3 and H4." [GOC:jl, PMID:9241414] xref: EC:2.3.1.- xref: GO:0004406 is_a: CCO:F0000813 ! histone acetyltransferase activity [Term] id: CCO:F0000816 name: histone deacetylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes." [EC:3.5.1.-, http://cancerweb.ncl.ac.uk/] xref: EC:3.5.1.- xref: GO:0004407 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0005179 ! protein deacetylase activity [Term] id: CCO:F0000817 name: holocytochrome-c synthase activity namespace: molecular_function def: "Catalysis of the reaction: holocytochrome c = apocytochrome c + heme." [EC:4.4.1.17] subset: gosubset_prok synonym: "cytochrome c heme-lyase activity" EXACT [EC:4.4.1.17] synonym: "cytochrome c synthase activity" RELATED [EC:4.4.1.17] synonym: "holocytochrome c synthetase activity" EXACT [EC:4.4.1.17] synonym: "holocytochrome-c apocytochrome-c-lyase (heme-forming)" EXACT [EC:4.4.1.17] synonym: "holocytochrome-c apocytochrome-c-lyase activity" EXACT [EC:4.4.1.17] xref: EC:4.4.1.17 xref: GO:0004408 xref: MetaCyc:HOLOCYTOCHROME-C-SYNTHASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0000818 name: homoaconitate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxybutane-1,2,4-tricarboxylate = but-1-ene-1,2,4-tricarboxylate + H2O." [EC:4.2.1.36] subset: gosubset_prok synonym: "(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]" RELATED [EC:4.2.1.36] synonym: "2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase activity" EXACT [EC:4.2.1.36] synonym: "cis-homoaconitase activity" EXACT [EC:4.2.1.36] synonym: "HACN activity" EXACT [EC:4.2.1.36] synonym: "homoaconitase activity" EXACT [EC:4.2.1.36] synonym: "Lys4" RELATED [EC:4.2.1.36] synonym: "LysF" RELATED [EC:4.2.1.36] xref: EC:4.2.1.36 xref: GO:0004409 xref: MetaCyc:HOMOACONITATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000819 name: homocitrate synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + H2O + 2-oxoglutarate = 2-hydroxybutane-1,2,4-tricarboxylate + CoA." [EC:2.3.3.14] comment: Note that this function was formerly EC:4.1.3.21. subset: gosubset_prok synonym: "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity" EXACT [EC:2.3.3.14] synonym: "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)" EXACT [EC:2.3.3.14] synonym: "acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)" EXACT [EC:2.3.3.14] synonym: "acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity" EXACT [EC:2.3.3.14] synonym: "homocitrate synthetase activity" EXACT [EC:2.3.3.14] xref: EC:2.3.3.14 xref: GO:0004410 xref: MetaCyc:HOMOCITRATE-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0000820 name: homogentisate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: homogentisate + O2 = 4-maleylacetoacetate." [EC:1.13.11.5] subset: gosubset_prok synonym: "homogentisate dioxygenase activity" EXACT [EC:1.13.11.5] synonym: "homogentisate oxidase activity" EXACT [EC:1.13.11.5] synonym: "homogentisate oxygenase activity" EXACT [EC:1.13.11.5] synonym: "homogentisate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.5] synonym: "homogentisic acid oxidase activity" EXACT [EC:1.13.11.5] synonym: "homogentisic acid oxygenase activity" EXACT [EC:1.13.11.5] synonym: "homogentisic oxygenase activity" EXACT [EC:1.13.11.5] synonym: "homogentisicase activity" EXACT [EC:1.13.11.5] xref: EC:1.13.11.5 xref: GO:0004411 xref: MetaCyc:HOMOGENTISATE-1 xref: Reactome:11355 xref: UM-BBD_enzymeID:e0081 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0000821 name: homoserine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+." [EC:1.1.1.3] subset: gosubset_prok xref: EC:1.1.1.3 xref: GO:0004412 xref: MetaCyc:HOMOSERDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000822 name: homoserine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-homoserine = ADP + O-phospho-L-homoserine." [EC:2.7.1.39] subset: gosubset_prok synonym: "ATP:L-homoserine O-phosphotransferase activity" EXACT [EC:2.7.1.39] synonym: "homoserine kinase (phosphorylating)" EXACT [EC:2.7.1.39] synonym: "HSK" RELATED [EC:2.7.1.39] xref: EC:2.7.1.39 xref: GO:0004413 xref: MetaCyc:HOMOSERKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004125 ! amino acid kinase activity [Term] id: CCO:F0000823 name: homoserine O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine." [EC:2.3.1.31] subset: gosubset_prok synonym: "acetyl-CoA:L-homoserine O-acetyltransferase activity" EXACT [EC:2.3.1.31] synonym: "homoserine acetyltransferase activity" EXACT [EC:2.3.1.31] synonym: "homoserine O-trans-acetylase activity" EXACT [EC:2.3.1.31] synonym: "homoserine transacetylase activity" BROAD [EC:2.3.1.31] synonym: "homoserine-O-transacetylase activity" EXACT [EC:2.3.1.31] synonym: "L-homoserine O-acetyltransferase activity" EXACT [EC:2.3.1.31] xref: EC:2.3.1.31 xref: GO:0004414 xref: MetaCyc:HOMOSERINE-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0000824 name: hyalurononglucosaminidase activity namespace: molecular_function def: "Catalysis of the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate." [EC:3.2.1.35] subset: gosubset_prok synonym: "chondroitinase activity" BROAD [EC:3.2.1.35] synonym: "chondroitinase I activity" EXACT [EC:3.2.1.35] synonym: "hyaluronate 4-glycanohydrolase activity" EXACT [EC:3.2.1.35] synonym: "hyaluronidase activity" BROAD [EC:3.2.1.35] synonym: "hyaluronoglucosaminidase activity" EXACT [] synonym: "hyaluronoglucosidase activity" EXACT [EC:3.2.1.35] xref: EC:3.2.1.35 xref: GO:0004415 xref: MetaCyc:3.2.1.35-RXN is_a: CCO:F0003024 ! hexosaminidase activity [Term] id: CCO:F0000825 name: hydroxyacylglutathione hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate." [EC:3.1.2.6] subset: gosubset_prok synonym: "acetoacetylglutathione hydrolase activity" EXACT [EC:3.1.2.6] synonym: "glyoxalase II activity" EXACT [EC:3.1.2.6] synonym: "S-(2-hydroxyacyl)glutathione hydrolase activity" EXACT [EC:3.1.2.6] synonym: "S-2-hydroxylacylglutathione hydrolase activity" EXACT [EC:3.1.2.6] xref: EC:3.1.2.6 xref: GO:0004416 xref: MetaCyc:GLYOXII-RXN is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0000826 name: hydroxyethylthiazole kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-methyl-5-(2-hydroxyethyl)-thiazole = ADP + 4-methyl-5-(2-phosphoethyl)-thiazole." [EC:2.7.1.50] subset: gosubset_prok synonym: "4-methyl-5-(beta-hydroxyethyl)thiazole kinase activity" EXACT [EC:2.7.1.50] synonym: "ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase activity" EXACT [EC:2.7.1.50] synonym: "hydroxyethylthiazole kinase (phosphorylating)" EXACT [EC:2.7.1.50] xref: EC:2.7.1.50 xref: GO:0004417 xref: MetaCyc:THIAZOLSYN3-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000827 name: hydroxymethylbilane synthase activity namespace: molecular_function def: "Catalysis of the reaction: 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH3." [EC:2.5.1.61] comment: Note that this function was formerly EC:4.3.1.8. subset: gosubset_prok synonym: "(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity" EXACT [EC:2.5.1.61] synonym: "(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)" EXACT [EC:2.5.1.61] synonym: "HMB-synthase activity" EXACT [EC:2.5.1.61] synonym: "porphobilinogen ammonia-lyase (polymerizing)" EXACT [EC:2.5.1.61] synonym: "porphobilinogen deaminase activity" EXACT [EC:2.5.1.61] synonym: "porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)" EXACT [EC:2.5.1.61] synonym: "pre-uroporphyrinogen synthase activity" EXACT [EC:2.5.1.61] synonym: "uroporphyrinogen I synthase activity" NARROW [EC:2.5.1.61] synonym: "uroporphyrinogen I synthetase activity" NARROW [EC:2.5.1.61] synonym: "uroporphyrinogen synthase activity" EXACT [EC:2.5.1.61] synonym: "uroporphyrinogen synthetase activity" EXACT [EC:2.5.1.61] xref: EC:2.5.1.61 xref: GO:0004418 xref: MetaCyc:OHMETHYLBILANESYN-RXN xref: Reactome:11374 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000828 name: hydroxymethylglutaryl-CoA lyase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate." [EC:4.1.3.4] subset: gosubset_prok synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.4] synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity" EXACT [EC:4.1.3.4] synonym: "3-hydroxy-3-methylglutarate-CoA lyase activity" EXACT [EC:4.1.3.4] synonym: "3-hydroxy-3-methylglutaryl CoA cleaving enzyme" RELATED [EC:4.1.3.4] synonym: "3-hydroxy-3-methylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.4] synonym: "3-hydroxy-3-methylglutaryl-CoA lyase activity" EXACT [EC:4.1.3.4] synonym: "HMG-CoA lyase activity" EXACT [EC:4.1.3.4] synonym: "hydroxymethylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.4] synonym: "hydroxymethylglutaryl coenzyme A-cleaving enzyme" RELATED [EC:4.1.3.4] xref: EC:4.1.3.4 xref: GO:0004419 xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN xref: Reactome:74178 is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0000829 name: hydroxymethylglutaryl-CoA reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+." [EC:1.1.1.34] subset: gosubset_prok synonym: "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [EC:1.1.1.34] synonym: "HMG-CoA reductase activity" BROAD [EC:1.1.1.34] xref: EC:1.1.1.34 xref: GO:0004420 xref: MetaCyc:1.1.1.34-RXN xref: Reactome:11408 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000830 name: hydroxymethylglutaryl-CoA synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + H2O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA." [EC:2.3.3.10] comment: Note that this function was formerly EC:4.1.3.5. subset: gosubset_prok synonym: "(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity" EXACT [EC:2.3.3.10] synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)" EXACT [EC:2.3.3.10] synonym: "3-hydroxy-3-methylglutaryl CoA synthetase activity" EXACT [EC:2.3.3.10] synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthase activity" EXACT [EC:2.3.3.10] synonym: "3-hydroxy-3-methylglutaryl coenzyme A synthetase activity" EXACT [EC:2.3.3.10] synonym: "3-hydroxy-3-methylglutaryl-CoA synthase activity" EXACT [EC:2.3.3.10] synonym: "3-hydroxy-3-methylglutaryl-coenzyme A synthase activity" EXACT [EC:2.3.3.10] synonym: "acetoacetyl coenzyme A transacetase activity" EXACT [EC:2.3.3.10] synonym: "acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.10] synonym: "beta-hydroxy-beta-methylglutaryl-CoA synthase activity" EXACT [EC:2.3.3.10] synonym: "HMG-CoA synthase activity" EXACT [EC:2.3.3.10] synonym: "hydroxymethylglutaryl coenzyme A synthase activity" EXACT [EC:2.3.3.10] synonym: "hydroxymethylglutaryl coenzyme A-condensing enzyme" RELATED [EC:2.3.3.10] synonym: "hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity" EXACT [EC:2.3.3.10] xref: EC:2.3.3.10 xref: GO:0004421 xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN xref: Reactome:74169 is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0000831 name: hypoxanthine phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate or GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.8, GOC:curators] comment: Note that GO uses one molecular function term for consistency with Enzyme Nomenclature; also, all hypoxanthine phosphoribosyltransferases identified to date can act on either hypoxanthine or guanine, as well as xanthine or 6-mercaptopurine. subset: gosubset_prok synonym: "6-hydroxypurine phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "6-mercaptopurine phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "GMP pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "GPRT" RELATED [EC:2.4.2.8] synonym: "guanine phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "guanine-hypoxanthine phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "guanosine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "guanosine phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "guanylate pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "guanylic pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "HGPRTase activity" EXACT [EC:2.4.2.8] synonym: "HPRT" RELATED [EC:2.4.2.8] synonym: "hypoxanthine-guanine phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "IMP diphosphorylase activity" EXACT [EC:2.4.2.8] synonym: "IMP pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "IMP-GMP pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "IMP:diphosphate phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "inosinate pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "inosine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "inosinic acid pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "inosinic pyrophosphorylase activity" EXACT [EC:2.4.2.8] synonym: "purine-6-thiol phosphoribosyltransferase activity" EXACT [EC:2.4.2.8] synonym: "Transphosphoribosidase activity" EXACT [EC:2.4.2.8] xref: EC:2.4.2.8 xref: GO:0004422 xref: MetaCyc:HYPOXANPRIBOSYLTRAN-RXN xref: Reactome:11410 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000832 name: iduronate-2-sulfatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin." [EC:3.1.6.13] subset: gosubset_prok synonym: "2-sulfo-L-iduronate 2-sulfatase activity" EXACT [EC:3.1.6.13] synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.13] synonym: "iduronate sulfatase activity" EXACT [EC:3.1.6.13] synonym: "iduronate sulfate sulfatase activity" EXACT [EC:3.1.6.13] synonym: "iduronate-2-sulfate sulfatase activity" EXACT [EC:3.1.6.13] synonym: "iduronate-2-sulphatase activity" EXACT [] synonym: "iduronide-2-sulfate sulfatase activity" EXACT [EC:3.1.6.13] synonym: "idurono-2-sulfatase activity" EXACT [EC:3.1.6.13] synonym: "L-iduronate 2-sulfate sulfatase activity" EXACT [EC:3.1.6.13] synonym: "L-iduronate-2-sulfate 2-sulfohydrolase activity" EXACT [EC:3.1.6.13] synonym: "L-idurono sulfate sulfatase activity" EXACT [EC:3.1.6.13] synonym: "L-iduronosulfatase activity" EXACT [EC:3.1.6.13] synonym: "sulfo-L-iduronate sulfatase activity" EXACT [EC:3.1.6.13] synonym: "sulfoiduronate sulfohydrolase activity" EXACT [EC:3.1.6.13] xref: EC:3.1.6.13 xref: GO:0004423 xref: MetaCyc:3.1.6.13-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0000833 name: imidazoleglycerol-phosphate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O." [EC:4.2.1.19] subset: gosubset_prok synonym: "D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]" RELATED [EC:4.2.1.19] synonym: "D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase activity" EXACT [EC:4.2.1.19] synonym: "IGP dehydratase activity" EXACT [EC:4.2.1.19] synonym: "imidazoleglycerol phosphate dehydratase activity" EXACT [] xref: EC:4.2.1.19 xref: GO:0004424 xref: MetaCyc:IMIDPHOSDEHYD-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000834 name: indole-3-glycerol-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O." [EC:4.1.1.48] subset: gosubset_prok synonym: "1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)" EXACT [EC:4.1.1.48] synonym: "1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]" RELATED [EC:4.1.1.48] synonym: "indole-3-glycerophosphate synthase activity" EXACT [EC:4.1.1.48] synonym: "indoleglycerol phosphate synthase activity" EXACT [EC:4.1.1.48] synonym: "indoleglycerol phosphate synthetase activity" EXACT [EC:4.1.1.48] xref: EC:4.1.1.48 xref: GO:0004425 xref: MetaCyc:IGPSYN-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000835 name: inorganic diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: diphosphate + H2O = 2 phosphate." [EC:3.6.1.1] subset: gosubset_prok synonym: "diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.1] synonym: "inorganic pyrophosphatase activity" EXACT [EC:3.6.1.1] synonym: "pyrophosphate phosphohydrolase activity" EXACT [EC:3.6.1.1] xref: EC:3.6.1.1 xref: GO:0004427 xref: MetaCyc:INORGPYROPHOSPHAT-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0000836 name: inositol or phosphatidylinositol kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol." [GOC:hb] subset: gosubset_prok synonym: "inositol/phosphatidylinositol kinase activity" EXACT [] xref: GO:0004428 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0000837 name: 1-phosphatidylinositol 4-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate." [EC:2.7.1.67, PMID:9759495] synonym: "ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity" EXACT [EC:2.7.1.67] synonym: "phosphatidylinositol 4-kinase activity" BROAD [EC:2.7.1.67] synonym: "phosphatidylinositol kinase (phosphorylating) activity" BROAD [EC:2.7.1.67] synonym: "phosphatidylinositol kinase activity" BROAD [EC:2.7.1.67] synonym: "PI 4-kinase activity" EXACT [EC:2.7.1.67] synonym: "PI kinase activity" BROAD [EC:2.7.1.67] synonym: "PI4-kinase activity" BROAD [EC:2.7.1.67] synonym: "PI4K" BROAD [EC:2.7.1.67] synonym: "PI4K-alpha activity" BROAD [EC:2.7.1.67] synonym: "PtdIns-4-kinase activity" BROAD [EC:2.7.1.67] synonym: "type II phosphatidylinositol kinase activity" RELATED [EC:2.7.1.67] xref: EC:2.7.1.67 xref: GO:0004430 xref: MetaCyc:1-PHOSPHATIDYLINOSITOL-KINASE-RXN is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000838 name: inositol or phosphatidylinositol phosphodiesterase activity namespace: molecular_function subset: gosubset_prok synonym: "inositol/phosphatidylinositol phosphodiesterase activity" EXACT [] xref: EC:3.1.4.- xref: GO:0004434 is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0000839 name: phosphoinositide phospholipase C activity namespace: molecular_function def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = D-myo-inositol 1,4,5-trisphosphate + diacylglycerol." [EC:3.1.4.11] subset: gosubset_prok synonym: "1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity" EXACT [EC:3.1.4.11] synonym: "1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity" EXACT [EC:3.1.4.11] synonym: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity" EXACT [] synonym: "monophosphatidylinositol phosphodiesterase activity" BROAD [EC:3.1.4.11] synonym: "phosphatidylinositol phospholipase C activity" EXACT [EC:3.1.4.11] synonym: "phosphatidylinositol-4,5-bisphosphate hydrolysis" RELATED [] synonym: "phosphoinositidase C activity" EXACT [EC:3.1.4.11] synonym: "PI-PLC activity" EXACT [EC:3.1.4.11] synonym: "triphosphoinositide phosphodiesterase activity" BROAD [EC:3.1.4.11] xref: EC:3.1.4.11 xref: GO:0004435 xref: MetaCyc:3.1.4.11-RXN is_a: CCO:F0000838 ! inositol or phosphatidylinositol phosphodiesterase activity is_a: CCO:F0001003 ! phospholipase C activity [Term] id: CCO:F0000840 name: phosphatidylinositol diacylglycerol-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol." [EC:4.6.1.13] comment: Note that this function was formerly EC:3.1.4.10. subset: gosubset_prok synonym: "1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)" EXACT [EC:4.6.1.13] synonym: "1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)" EXACT [EC:4.6.1.13] synonym: "1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming)" EXACT [EC:4.6.1.13] synonym: "1-phosphatidylinositol phosphodiesterase activity" EXACT [] synonym: "monophosphatidylinositol phosphodiesterase activity" BROAD [EC:4.6.1.13] xref: EC:4.6.1.13 xref: GO:0004436 xref: MetaCyc:3.1.4.10-RXN is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0000841 name: inositol or phosphatidylinositol phosphatase activity namespace: molecular_function def: "Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol." [GOC:hb] subset: gosubset_prok synonym: "inositol/phosphatidylinositol phosphatase activity" EXACT [] xref: GO:0004437 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0000842 name: phosphatidylinositol-3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate." [EC:3.1.3.64] comment: Note that this function includes EC:3.1.3.65. synonym: "1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.64] synonym: "D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.64] synonym: "inositol 1,3-bisphosphate phosphatase activity" EXACT [EC:3.1.3.64] synonym: "inositol-1,3-bisphosphate 3-phosphatase activity" EXACT [EC:3.1.3.64] synonym: "inositol-1,4,-bisphosphate 3-phosphatase activity" EXACT [] synonym: "inositol-polyphosphate 3-phosphatase activity" EXACT [EC:3.1.3.64] synonym: "phosphatidyl-3-phosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.64] xref: EC:3.1.3.64 xref: GO:0004438 xref: GO:0016315 xref: MetaCyc:PHOSPHATIDYLINOSITOL-3-PHOSPHATASE-RXN is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity is_a: CCO:F0005684 ! lipid phosphatase activity [Term] id: CCO:F0000843 name: phosphoinositide 5-phosphatase activity namespace: molecular_function def: "Catalysis of the removal the of the 5-phosphate group of a phosphatidylinositol phosphate." [GOC:elh] subset: gosubset_prok synonym: "polyphosphoinositol lipid 5-phosphatase activity" EXACT [] xref: GO:0034595 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0000844 name: inositol-1,4-bisphosphate 1-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate." [EC:3.1.3.57, GOC:hb] synonym: "1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.57] synonym: "inositol polyphosphate 1-phosphatase activity" BROAD [EC:3.1.3.57] synonym: "inositol-polyphosphate 1-phosphatase activity" EXACT [EC:3.1.3.57] xref: EC:3.1.3.57 xref: GO:0004441 xref: MetaCyc:3.1.3.57-RXN is_a: CCO:F0003119 ! inositol bisphosphate phosphatase activity [Term] id: CCO:F0000845 name: inositol-polyphosphate 5-phosphatase activity namespace: molecular_function def: "Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate." [EC:3.1.3.56] synonym: "1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity" EXACT [EC:3.1.3.56] synonym: "5PTase activity" RELATED [EC:3.1.3.56] synonym: "D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "inosine triphosphatase activity" RELATED [EC:3.1.3.56] synonym: "inositol 1,4,5-trisphosphate phosphatase activity" BROAD [EC:3.1.3.56] synonym: "inositol phosphate 5-phosphomonoesterase activity" BROAD [EC:3.1.3.56] synonym: "inositol polyphosphate-5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "inositol triphosphate 5-phosphomonoesterase activity" EXACT [] synonym: "inositol trisphosphate phosphomonoesterase activity" BROAD [EC:3.1.3.56] synonym: "inositol-1,4,5-trisphosphate 5-phosphatase activity" EXACT [] synonym: "inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "Ins(1,4,5)P(3) 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "Ins(1,4,5)P3 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "InsP3/Ins(1,3,4,5)P4 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "L-myo-inositol 1,4,5-trisphosphate-monoesterase activity" BROAD [EC:3.1.3.56] synonym: "myo-inositol-1,4,5-trisphosphate 5-phosphatase activity" EXACT [EC:3.1.3.56] synonym: "type I inositol-polyphosphate phosphatase activity" RELATED [EC:3.1.3.56] synonym: "type II inositol polyphosphate 5-phosphatase activity" RELATED [] synonym: "type II inositol-1,4,5-trisphosphate 5-phosphatase activity" NARROW [] xref: EC:3.1.3.56 xref: GO:0004445 xref: MetaCyc:3.1.3.56-RXN is_a: CCO:F0006172 ! inositol trisphosphate phosphatase activity [Term] id: CCO:F0000846 name: multiple inositol-polyphosphate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate." [EC:3.1.3.62] synonym: "1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity" EXACT [EC:3.1.3.62] synonym: "inositol tetrakisphosphate phosphomonoesterase activity" EXACT [EC:3.1.3.62] synonym: "MIPP activity" EXACT [EC:3.1.3.62] xref: EC:3.1.3.62 xref: GO:0004446 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0000847 name: iodide peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: iodide + H2O2 = iodine + 2 H2O." [EC:1.11.1.8] synonym: "iodide peroxidase-tyrosine iodinase activity" EXACT [EC:1.11.1.8] synonym: "iodide:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.8] synonym: "iodinase activity" RELATED [EC:1.11.1.8] synonym: "iodoperoxidase (heme type)" EXACT [EC:1.11.1.8] synonym: "iodotyrosine deiodase activity" EXACT [EC:1.11.1.8] synonym: "iodotyrosine deiodinase activity" EXACT [EC:1.11.1.8] synonym: "monoiodotyrosine deiodinase activity" EXACT [EC:1.11.1.8] synonym: "thyroid peroxidase activity" RELATED [EC:1.11.1.8] synonym: "thyroperoxidase activity" RELATED [EC:1.11.1.8] synonym: "TPO activity" RELATED [EC:1.11.1.8] synonym: "tyrosine iodinase activity" EXACT [EC:1.11.1.8] xref: EC:1.11.1.8 xref: GO:0004447 xref: MetaCyc:IODIDE-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0000848 name: isocitrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor." [EC:1.1.1.41, EC:1.1.1.42] subset: gosubset_prok synonym: "beta-ketoglutaric-isocitric carboxylase activity" EXACT [EC:1.1.1.-] synonym: "IDH activity" EXACT [EC:1.1.1.-] synonym: "IDP activity" EXACT [EC:1.1.1.-] synonym: "IDP1" RELATED [EC:1.1.1.-] synonym: "IDP2" RELATED [EC:1.1.1.-] synonym: "IDP3" RELATED [EC:1.1.1.-] synonym: "isocitric acid dehydrogenase activity" EXACT [EC:1.1.1.-] synonym: "isocitric dehydrogenase activity" EXACT [EC:1.1.1.-] synonym: "oxalosuccinate carboxylase activity" EXACT [EC:1.1.1.-] synonym: "oxalosuccinate decarboxylase activity" EXACT [EC:1.1.1.-] synonym: "oxalsuccinic decarboxylase activity" EXACT [EC:1.1.1.-] xref: EC:1.1.1.- xref: GO:0004448 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000849 name: isocitrate dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+." [EC:1.1.1.41] subset: gosubset_prok synonym: "isocitrate dehydrogenase (NAD) activity" EXACT [EC:1.1.1.41] synonym: "isocitrate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.41] synonym: "NAD dependent isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] synonym: "NAD isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] synonym: "NAD isocitric dehydrogenase activity" EXACT [EC:1.1.1.41] synonym: "NAD-linked isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] synonym: "NAD-specific isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] synonym: "nicotinamide adenine dinucleotide isocitrate dehydrogenase activity" EXACT [EC:1.1.1.41] xref: EC:1.1.1.41 xref: GO:0004449 xref: MetaCyc:ISOCITRATE-DEHYDROGENASE-(NAD+)-RXN xref: Reactome:11496 is_a: CCO:F0000848 ! isocitrate dehydrogenase activity [Term] id: CCO:F0000850 name: isocitrate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+." [EC:1.1.1.42] subset: gosubset_prok synonym: "dual-cofactor-specific isocitrate dehydrogenase activity" RELATED [EC:1.1.1.42] synonym: "isocitrate (NADP) dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "isocitrate dehydrogenase (NADP) activity" EXACT [EC:1.1.1.42] synonym: "isocitrate dehydrogenase (NADP-dependent) activity" EXACT [EC:1.1.1.42] synonym: "isocitrate:NADP+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.42] synonym: "NADP isocitric dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "NADP(+)-ICDH activity" EXACT [EC:1.1.1.42] synonym: "NADP(+)-IDH activity" EXACT [EC:1.1.1.42] synonym: "NADP(+)-linked isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "NADP-dependent isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "NADP-dependent isocitric dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "NADP-linked isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "NADP-specific isocitrate dehydrogenase activity" EXACT [EC:1.1.1.42] synonym: "triphosphopyridine nucleotide-linked isocitrate dehydrogenase- activity" RELATED [EC:1.1.1.42] xref: EC:1.1.1.42 xref: GO:0004450 xref: MetaCyc:ISOCITDEH-RXN is_a: CCO:F0000848 ! isocitrate dehydrogenase activity [Term] id: CCO:F0000851 name: isocitrate lyase activity namespace: molecular_function def: "Catalysis of the reaction: isocitrate = succinate + glyoxylate." [EC:4.1.3.1] subset: gosubset_prok synonym: "ICL activity" EXACT [EC:4.1.3.1] synonym: "isocitrase activity" EXACT [EC:4.1.3.1] synonym: "isocitratase activity" EXACT [EC:4.1.3.1] synonym: "isocitrate glyoxylate-lyase (succinate-forming)" EXACT [EC:4.1.3.1] synonym: "isocitrate glyoxylate-lyase activity" EXACT [EC:4.1.3.1] synonym: "isocitritase activity" EXACT [EC:4.1.3.1] synonym: "threo-DS-isocitrate glyoxylate-lyase activity" EXACT [EC:4.1.3.1] xref: EC:4.1.3.1 xref: GO:0004451 xref: MetaCyc:ISOCIT-CLEAV-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0000852 name: isopentenyl-diphosphate delta-isomerase activity namespace: molecular_function def: "Catalysis of the isomerization of isopentenyl diphosphate into dimethylallyl diphosphate." [EC:5.3.3.2] subset: gosubset_prok synonym: "IPP isomerase activity" EXACT [EC:5.3.3.2] synonym: "ipp isomerase activity" EXACT [EC:5.3.3.2] synonym: "isopentenyl-diphosphate D-isomerase activity" EXACT [] synonym: "isopentenyl-diphosphate delta3-delta2-isomerase activity" EXACT [EC:5.3.3.2] synonym: "isopentenylpyrophosphate delta-isomerase activity" EXACT [EC:5.3.3.2] synonym: "isopentenylpyrophosphate Delta-isomerase activity" EXACT [EC:5.3.3.2] synonym: "isopentenylpyrophosphate isomerase activity" EXACT [EC:5.3.3.2] synonym: "methylbutenylpyrophosphate isomerase activity" EXACT [EC:5.3.3.2] xref: EC:5.3.3.2 xref: GO:0004452 xref: MetaCyc:IPPISOM-RXN xref: Reactome:11501 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0000853 name: juvenile-hormone esterase activity namespace: molecular_function def: "Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone." [EC:3.1.1.59, EMBL:AF304352] synonym: "JH esterase activity" EXACT [EC:3.1.1.59] synonym: "JH-esterase activity" EXACT [EC:3.1.1.59] synonym: "juvenile hormone analog esterase activity" EXACT [EC:3.1.1.59] synonym: "juvenile hormone carboxyesterase activity" EXACT [EC:3.1.1.59] synonym: "methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase activity" EXACT [EC:3.1.1.59] xref: EC:3.1.1.59 xref: GO:0004453 xref: MetaCyc:JUVENILE-HORMONE-ESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0000854 name: ketohexokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate." [EC:2.7.1.3] subset: gosubset_prok synonym: "ATP:D-fructose 1-phosphotransferase activity" EXACT [EC:2.7.1.3] synonym: "hepatic fructokinase activity" NARROW [EC:2.7.1.3] synonym: "ketohexokinase (phosphorylating)" EXACT [EC:2.7.1.3] xref: EC:2.7.1.3 xref: GO:0004454 xref: MetaCyc:KETOHEXOKINASE-RXN xref: Reactome:11506 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0000855 name: ketol-acid reductoisomerase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+." [EC:1.1.1.86] subset: gosubset_prok synonym: "(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)" EXACT [EC:1.1.1.86] synonym: "2-hydroxy-3-keto acid reductoisomerase activity" EXACT [EC:1.1.1.86] synonym: "acetohydroxy acid isomeroreductase activity" EXACT [EC:1.1.1.86] synonym: "acetohydroxy acid reductoisomerase activity" EXACT [EC:1.1.1.86] synonym: "acetolactate reductoisomerase activity" EXACT [EC:1.1.1.86] synonym: "alpha-keto-beta-hydroxylacyl reductoisomerase activity" EXACT [EC:1.1.1.86] synonym: "dihydroxyisovalerate (isomerizing) dehydrogenase activity" EXACT [EC:1.1.1.86] synonym: "dihydroxyisovalerate dehydrogenase (isomerizing) activity" EXACT [EC:1.1.1.86] synonym: "isomeroreductase activity" EXACT [EC:1.1.1.86] synonym: "ketol acid reductoisomerase activity" EXACT [EC:1.1.1.86] synonym: "reductoisomerase activity" EXACT [EC:1.1.1.86] xref: EC:1.1.1.86 xref: GO:0004455 xref: MetaCyc:ACETOLACTREDUCTOISOM-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000856 name: phosphogluconate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O." [EC:4.2.1.12] subset: gosubset_prok synonym: "6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)" EXACT [EC:4.2.1.12] synonym: "6-phospho-D-gluconate hydro-lyase activity" EXACT [EC:4.2.1.12] synonym: "6-phosphogluconate dehydrase activity" EXACT [EC:4.2.1.12] synonym: "6-phosphogluconate dehydratase activity" EXACT [EC:4.2.1.12] synonym: "6-phosphogluconic dehydrase activity" EXACT [EC:4.2.1.12] synonym: "gluconate 6-phosphate dehydratase activity" EXACT [EC:4.2.1.12] synonym: "gluconate-6-phosphate dehydratase activity" EXACT [EC:4.2.1.12] xref: EC:4.2.1.12 xref: GO:0004456 xref: MetaCyc:PGLUCONDEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000857 name: lactate dehydrogenase activity namespace: molecular_function def: "Catalysis of the oxidation of lactate to produce pyruvate." [GOC:ai] subset: gosubset_prok xref: GO:0004457 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0000858 name: D-lactate dehydrogenase (cytochrome) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c." [EC:1.1.2.4] subset: gosubset_prok synonym: "(R)-lactate:ferricytochrome-c 2-oxidoreductase activity" EXACT [EC:1.1.2.4] synonym: "cytochrome-dependent D-(-)-lactate dehydrogenase activity" EXACT [EC:1.1.2.4] synonym: "D-(-)-lactic cytochrome c reductase activity" EXACT [EC:1.1.2.4] synonym: "D-lactate (cytochrome) dehydrogenase activity" EXACT [EC:1.1.2.4] synonym: "D-lactate ferricytochrome c oxidoreductase activity" EXACT [EC:1.1.2.4] synonym: "D-lactate-cytochrome c reductase activity" EXACT [EC:1.1.2.4] synonym: "lactic acid dehydrogenase activity" BROAD [EC:1.1.2.4] xref: EC:1.1.2.4 xref: GO:0004458 xref: MetaCyc:D-LACTATE-DEHYDROGENASE-(CYTOCHROME)-RXN is_a: CCO:F0000857 ! lactate dehydrogenase activity is_a: CCO:F0003456 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor [Term] id: CCO:F0000859 name: L-lactate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+." [EC:1.1.1.27] subset: gosubset_prok synonym: "L-lactic acid dehydrogenase activity" EXACT [EC:1.1.1.27] synonym: "L-lactic dehydrogenase activity" EXACT [EC:1.1.1.27] xref: EC:1.1.1.27 xref: GO:0004459 xref: MetaCyc:L-LACTATE-DEHYDROGENASE-RXN xref: Reactome:11515 is_a: CCO:F0000857 ! lactate dehydrogenase activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000860 name: L-lactate dehydrogenase (cytochrome) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c." [EC:1.1.2.3] subset: gosubset_prok synonym: "(S)-lactate:ferricytochrome-c 2-oxidoreductase activity" EXACT [EC:1.1.2.3] synonym: "cytochrome b2" RELATED [] synonym: "cytochrome b2 (flavin-free derivative of flavocytochrome b2)" RELATED [EC:1.1.2.3] synonym: "dehydrogenase, lactate (cytochrome)" EXACT [EC:1.1.2.3] synonym: "flavocytochrome b2" RELATED [EC:1.1.2.3] synonym: "L(+)-lactate:cytochrome c oxidoreductase activity" EXACT [EC:1.1.2.3] synonym: "L-lactate cytochrome c oxidoreductase activity" EXACT [EC:1.1.2.3] synonym: "L-lactate cytochrome c reductase activity" EXACT [EC:1.1.2.3] synonym: "L-lactate ferricytochrome c oxidoreductase activity" EXACT [EC:1.1.2.3] synonym: "lactate dehydrogenase (cytochrome)" EXACT [EC:1.1.2.3] synonym: "lactic acid dehydrogenase activity" BROAD [EC:1.1.2.3] synonym: "lactic cytochrome c reductase activity" EXACT [EC:1.1.2.3] xref: EC:1.1.2.3 xref: GO:0004460 xref: MetaCyc:L-LACTATE-DEHYDROGENASE-(CYTOCHROME)-RXN is_a: CCO:F0000857 ! lactate dehydrogenase activity is_a: CCO:F0003456 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor [Term] id: CCO:F0000861 name: lactose synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose." [EC:2.4.1.22] synonym: "lactose synthetase activity" EXACT [EC:2.4.1.22] synonym: "UDP-galactose-glucose galactosyltransferase activity" EXACT [EC:2.4.1.22] synonym: "UDP-galactose:D-glucose 4-beta-D-galactotransferase activity" EXACT [EC:2.4.1.22] synonym: "UDPgalactose-glucose galactosyltransferase activity" EXACT [EC:2.4.1.22] synonym: "UDPgalactose:D-glucose 4-beta-D-galactotransferase activity" EXACT [EC:2.4.1.22] synonym: "uridine diphosphogalactose-glucose galactosyltransferase activity" EXACT [EC:2.4.1.22] xref: EC:2.4.1.22 xref: GO:0004461 xref: MetaCyc:LACTOSE-SYNTHASE-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0000862 name: lactoylglutathione lyase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal." [EC:4.4.1.5] subset: gosubset_prok synonym: "(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity" EXACT [EC:4.4.1.5] synonym: "(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)" EXACT [EC:4.4.1.5] synonym: "aldoketomutase activity" EXACT [EC:4.4.1.5] synonym: "glyoxalase I activity" EXACT [EC:4.4.1.5] synonym: "glyoxylase I" RELATED [EC:4.4.1.5] synonym: "ketone-aldehyde mutase activity" EXACT [EC:4.4.1.5] synonym: "methylglyoxalase activity" EXACT [EC:4.4.1.5] xref: EC:4.4.1.5 xref: GO:0004462 xref: MetaCyc:GLYOXI-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0000863 name: leukotriene-A4 hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O = (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate." [EC:3.3.2.6] subset: gosubset_prok synonym: "(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity" EXACT [EC:3.3.2.6] synonym: "leukotriene A(4) hydrolase activity" EXACT [EC:3.3.2.6] synonym: "leukotriene A4 hydrolase activity" EXACT [EC:3.3.2.6] synonym: "LTA-4 hydrolase activity" EXACT [EC:3.3.2.6] synonym: "LTA4 hydrolase activity" EXACT [EC:3.3.2.6] synonym: "LTA4H" RELATED [EC:3.3.2.6] xref: EC:3.3.2.6 xref: GO:0004463 xref: MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0000864 name: leukotriene-C4 synthase activity namespace: molecular_function def: "Catalysis of the reaction: leukotriene C4 = leukotriene A4 + glutathione." [EC:2.5.1.37] comment: Note that this function was EC:2.5.1.37. synonym: "(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)" EXACT [EC:4.4.1.20] synonym: "(7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)" EXACT [EC:4.4.1.20] synonym: "leukotriene A(4):glutathione S-leukotrienyltransferase activity" EXACT [EC:4.4.1.20] synonym: "leukotriene A4:glutathione S-leukotrienyltransferase activity" EXACT [EC:4.4.1.20] synonym: "leukotriene C(4) synthetase activity" EXACT [EC:4.4.1.20] synonym: "leukotriene C4 synthetase activity" EXACT [EC:4.4.1.20] synonym: "leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)" EXACT [EC:4.4.1.20] synonym: "LTC(4) synthase activity" EXACT [EC:4.4.1.20] synonym: "LTC(4) synthetase activity" EXACT [EC:4.4.1.20] synonym: "LTC4 synthase activity" EXACT [EC:4.4.1.20] synonym: "LTC4 synthetase activity" EXACT [EC:4.4.1.20] xref: EC:4.4.1.20 xref: GO:0004464 xref: MetaCyc:LEUKOTRIENE-C(4)-SYNTHASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0000865 name: lipoprotein lipase activity namespace: molecular_function def: "Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate." [EC:3.1.1.34] synonym: "clearing factor lipase activity" RELATED [EC:3.1.1.34] synonym: "diacylglycerol hydrolase activity" EXACT [EC:3.1.1.34] synonym: "diacylglycerol lipase activity" EXACT [EC:3.1.1.34] synonym: "diglyceride lipase activity" EXACT [EC:3.1.1.34] synonym: "lipemia-clearing factor" RELATED [EC:3.1.1.34] synonym: "postheparin esterase activity" EXACT [EC:3.1.1.34] synonym: "postheparin lipase activity" EXACT [EC:3.1.1.34] synonym: "triacylglycero-protein acylhydrolase activity" EXACT [EC:3.1.1.34] xref: EC:3.1.1.34 xref: GO:0004465 xref: MetaCyc:LIPOPROTEIN-LIPASE-RXN xref: Reactome:11541 is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0003111 ! lipase activity [Term] id: CCO:F0000866 name: long-chain-acyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF." [EC:1.3.99.13] subset: gosubset_prok synonym: "long-chain acyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.13] synonym: "long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase activity" EXACT [EC:1.3.99.13] synonym: "long-chain-acyl-CoA:acceptor 2,3-oxidoreductase activity" EXACT [EC:1.3.99.13] synonym: "palmitoyl-CoA dehydrogenase activity" EXACT [EC:1.3.99.13] synonym: "palmitoyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.13] xref: EC:1.3.99.13 xref: GO:0004466 xref: MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN is_a: CCO:F0000480 ! acyl-CoA dehydrogenase activity [Term] id: CCO:F0000867 name: long-chain-fatty-acid-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C12-18." [EC:6.2.1.3] subset: gosubset_prok synonym: "ACS3" NARROW [EC:6.2.1.3] synonym: "acyl-activating enzyme activity" BROAD [EC:6.2.1.3] synonym: "acyl-CoA synthetase activity" EXACT [EC:6.2.1.3] synonym: "arachidonyl-CoA synthetase" NARROW [EC:6.2.1.3] synonym: "FAA1" NARROW [EC:6.2.1.3] synonym: "fatty acid thiokinase (long chain) activity" EXACT [EC:6.2.1.3] synonym: "fatty acid thiokinase (long-chain) activity" EXACT [EC:6.2.1.3] synonym: "LCFA synthetase activity" EXACT [EC:6.2.1.3] synonym: "lignoceroyl-CoA synthase activity" EXACT [EC:6.2.1.3] synonym: "long chain fatty acyl-CoA synthetase activity" EXACT [EC:6.2.1.3] synonym: "long-chain acyl CoA synthetase activity" EXACT [EC:6.2.1.3] synonym: "long-chain acyl-CoA synthetase activity" EXACT [] synonym: "long-chain acyl-CoA synthetase I" NARROW [EC:6.2.1.3] synonym: "long-chain acyl-CoA synthetase II" NARROW [EC:6.2.1.3] synonym: "long-chain acyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.3] synonym: "long-chain fatty acid activation" RELATED [] synonym: "long-chain fatty acid-CoA ligase activity" EXACT [] synonym: "long-chain fatty acyl coenzyme A synthetase activity" EXACT [EC:6.2.1.3] synonym: "long-chain-fatty-acyl-CoA synthetase activity" EXACT [] synonym: "oleoyl-CoA synthetase" NARROW [EC:6.2.1.3] synonym: "palmitoyl coenzyme A synthetase" NARROW [EC:6.2.1.3] synonym: "palmitoyl-CoA ligase" NARROW [EC:6.2.1.3] synonym: "palmitoyl-CoA synthase" NARROW [EC:6.2.1.3] synonym: "pristanoyl-CoA synthetase" NARROW [EC:6.2.1.3] synonym: "stearoyl-CoA synthetase" NARROW [EC:6.2.1.3] synonym: "thiokinase" RELATED [EC:6.2.1.3] xref: EC:6.2.1.3 xref: GO:0004467 xref: MetaCyc:ACYLCOASYN-RXN xref: MetaCyc:PWY-5143 xref: Reactome:11544 xref: UM-BBD_enzymeID:e0025 is_a: CCO:F0002996 ! fatty-acid ligase activity [Term] id: CCO:F0000868 name: lysine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine." [EC:2.3.1.32] subset: gosubset_prok synonym: "acetyl-phosphate:L-lysine 6-N-acetyltransferase activity" EXACT [EC:2.3.1.32] synonym: "acetyl-phosphate:L-lysine N6-acetyltransferase activity" EXACT [EC:2.3.1.32] synonym: "LAT activity" EXACT [EC:2.3.1.32] synonym: "lysine acetyltransferase activity" EXACT [] synonym: "lysine N(6)-acetyltransferase activity" EXACT [EC:2.3.1.32] synonym: "lysine N6-acetyltransferase activity" EXACT [EC:2.3.1.32] xref: EC:2.3.1.32 xref: GO:0004468 xref: MetaCyc:LYSINE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0000869 name: malic enzyme activity namespace: molecular_function def: "Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "pyruvic-malic carboxylase activity" EXACT [EC:1.1.1.39] xref: GO:0004470 is_a: CCO:F0003217 ! malate dehydrogenase activity [Term] id: CCO:F0000870 name: malate dehydrogenase (decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. Does not decarboxylate oxaloacetate." [EC:1.1.1.39] subset: gosubset_prok synonym: "'malic' enzyme" RELATED [EC:1.1.1.39] synonym: "(S)-malate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.39] synonym: "NAD-malic enzyme activity" BROAD [EC:1.1.1.39] synonym: "NAD-specific malic enzyme" RELATED [EC:1.1.1.39] xref: EC:1.1.1.39 xref: GO:0004471 xref: MetaCyc:1.1.1.39-RXN is_a: CCO:F0000869 ! malic enzyme activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000871 name: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+. Also decarboxylates oxaloacetate." [EC:1.1.1.40] subset: gosubset_prok synonym: "'malic' enzyme" RELATED [EC:1.1.1.40] synonym: "(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [EC:1.1.1.40] synonym: "L-malate:NADP oxidoreductase activity" EXACT [EC:1.1.1.40] synonym: "malate dehydrogenase (decarboxylating, NADP)" EXACT [EC:1.1.1.40] synonym: "malate dehydrogenase (NADP, decarboxylating)" EXACT [EC:1.1.1.40] synonym: "NADP-linked decarboxylating malic enzyme" RELATED [EC:1.1.1.40] synonym: "NADP-malic enzyme activity" EXACT [EC:1.1.1.40] synonym: "NADP-specific malate dehydrogenase activity" EXACT [EC:1.1.1.40] synonym: "NADP-specific malic enzyme" RELATED [EC:1.1.1.40] xref: EC:1.1.1.40 xref: GO:0004473 xref: MetaCyc:MALIC-NADP-RXN is_a: CCO:F0000869 ! malic enzyme activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000872 name: malate synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + H2O + glyoxylate = L-malate + CoA." [EC:2.3.3.9] comment: Note that this function was formerly EC:4.1.3.2. subset: gosubset_prok synonym: "acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.9] synonym: "glyoxylate transacetase activity" EXACT [EC:2.3.3.9] synonym: "glyoxylate transacetylase activity" EXACT [EC:2.3.3.9] synonym: "glyoxylic transacetase activity" EXACT [EC:2.3.3.9] synonym: "L-malate glyoxylate-lyase (CoA-acetylating) activity" EXACT [EC:2.3.3.9] synonym: "malate condensing enzyme activity" RELATED [EC:2.3.3.9] synonym: "malate synthetase activity" EXACT [EC:2.3.3.9] synonym: "malic synthetase activity" EXACT [EC:2.3.3.9] synonym: "malic-condensing enzyme activity" RELATED [EC:2.3.3.9] xref: EC:2.3.3.9 xref: GO:0004474 xref: MetaCyc:MALSYN-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0000873 name: mannose-1-phosphate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose." [EC:2.7.7.13] subset: gosubset_prok synonym: "GDP-mannose pyrophosphorylase activity" RELATED [EC:2.7.7.13] synonym: "GTP-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.13] synonym: "GTP:alpha-D-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.13] synonym: "GTP:mannose-1-phosphate guanylyltransferase activity" EXACT [] synonym: "guanosine 5'-diphospho-D-mannose pyrophosphorylase activity" EXACT [EC:2.7.7.13] synonym: "guanosine diphosphomannose pyrophosphorylase activity" EXACT [EC:2.7.7.13] synonym: "guanosine triphosphate-mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.13] synonym: "mannose 1-phosphate guanylyltransferase (guanosine triphosphate)" EXACT [EC:2.7.7.13] synonym: "PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase)" RELATED [EC:2.7.7.13] xref: EC:2.7.7.13 xref: GO:0004475 xref: MetaCyc:2.7.7.13-RXN is_a: CCO:F0002242 ! mannose-phosphate guanylyltransferase activity [Term] id: CCO:F0000874 name: mannose-6-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate." [EC:5.3.1.8] subset: gosubset_prok synonym: "D-mannose-6-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.8] synonym: "D-mannose-6-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.8] synonym: "mannose phosphate isomerase activity" EXACT [EC:5.3.1.8] synonym: "phosphohexoisomerase activity" BROAD [EC:5.3.1.8] synonym: "phosphohexomutase activity" BROAD [EC:5.3.1.8] synonym: "phosphomannoisomerase activity" EXACT [EC:5.3.1.8] synonym: "phosphomannose isomerase activity" EXACT [EC:5.3.1.8] xref: EC:5.3.1.8 xref: GO:0004476 xref: MetaCyc:MANNPISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0000875 name: methenyltetrahydrofolate cyclohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate." [EC:3.5.4.9] subset: gosubset_prok synonym: "5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)" EXACT [EC:3.5.4.9] synonym: "citrovorum factor cyclodehydrase activity" EXACT [EC:3.5.4.9] synonym: "formyl-methenyl-methylenetetrahydrofolate synthetase (combined)" EXACT [EC:3.5.4.9] xref: EC:3.5.4.9 xref: GO:0004477 xref: MetaCyc:METHENYLTHFCYCLOHYDRO-RXN is_a: CCO:F0004139 ! cyclohydrolase activity [Term] id: CCO:F0000876 name: methionine adenosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine." [EC:2.5.1.6] subset: gosubset_prok synonym: "adenosylmethionine synthetase activity" EXACT [EC:2.5.1.6] synonym: "AdoMet synthetase activity" EXACT [EC:2.5.1.6] synonym: "ATP-methionine adenosyltransferase activity" EXACT [EC:2.5.1.6] synonym: "ATP:L-methionine S-adenosyltransferase activity" EXACT [EC:2.5.1.6] synonym: "methionine S-adenosyltransferase activity" EXACT [EC:2.5.1.6] synonym: "methionine-activating enzyme" RELATED [EC:2.5.1.6] synonym: "S-adenosyl-L-methionine synthetase activity" EXACT [EC:2.5.1.6] synonym: "S-adenosylmethionine synthase activity" EXACT [EC:2.5.1.6] synonym: "S-adenosylmethionine synthetase activity" EXACT [EC:2.5.1.6] xref: EC:2.5.1.6 xref: GO:0004478 xref: MetaCyc:S-ADENMETSYN-RXN xref: Reactome:11567 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0000877 name: methionyl-tRNA formyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA." [EC:2.1.2.9] subset: gosubset_prok synonym: "10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity" EXACT [EC:2.1.2.9] synonym: "formylmethionyl-transfer ribonucleic synthetase activity" EXACT [EC:2.1.2.9] synonym: "methionyl ribonucleic formyltransferase activity" EXACT [EC:2.1.2.9] synonym: "methionyl-transfer ribonucleate methyltransferase activity" RELATED [EC:2.1.2.9] synonym: "methionyl-transfer ribonucleic transformylase activity" EXACT [EC:2.1.2.9] synonym: "methionyl-transfer RNA transformylase activity" EXACT [EC:2.1.2.9] synonym: "methionyl-tRNA Met formyltransferase activity" EXACT [EC:2.1.2.9] synonym: "methionyl-tRNA transformylase activity" EXACT [EC:2.1.2.9] synonym: "N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity" EXACT [EC:2.1.2.9] synonym: "N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity" EXACT [EC:2.1.2.9] xref: EC:2.1.2.9 xref: GO:0004479 xref: MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0000878 name: methylene-fatty-acyl-phospholipid synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid." [EC:2.1.1.16] synonym: "cyclopropane synthetase activity" BROAD [EC:2.1.1.16] synonym: "S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating)" EXACT [EC:2.1.1.16] synonym: "unsaturated-phospholipid methyltransferase activity" BROAD [EC:2.1.1.16] xref: EC:2.1.1.16 xref: GO:0004481 xref: MetaCyc:2.1.1.16-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0000879 name: mRNA (guanine-N7-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA; m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine." [EC:2.1.1.56] synonym: "guanine-7-methyltransferase activity" EXACT [EC:2.1.1.56] synonym: "messenger ribonucleate guanine 7-methyltransferase activity" EXACT [EC:2.1.1.56] synonym: "messenger RNA guanine 7-methyltransferase activity" EXACT [EC:2.1.1.56] synonym: "S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity" EXACT [EC:2.1.1.56] synonym: "S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity" EXACT [EC:2.1.1.56] xref: EC:2.1.1.56 xref: GO:0004482 xref: MetaCyc:MRNA-(GUANINE-N7-)-METHYLTRANSFERASE-RXN xref: Reactome:72079 is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0001761 ! mRNA methyltransferase activity [Term] id: CCO:F0000880 name: mRNA (nucleoside-2'-O-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine." [EC:2.1.1.57] subset: gosubset_prok synonym: "messenger ribonucleate nucleoside 2'-methyltransferase activity" EXACT [EC:2.1.1.57] synonym: "messenger RNA (nucleoside-2'-)-methyltransferase activity" EXACT [EC:2.1.1.57] synonym: "mRNA (adenosine-2'-O-)-methyltransferase activity" EXACT [EC:2.1.1.57] synonym: "S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity" EXACT [EC:2.1.1.57] xref: EC:2.1.1.57 xref: GO:0004483 xref: MetaCyc:2.1.1.57-RXN is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0001761 ! mRNA methyltransferase activity [Term] id: CCO:F0000881 name: mRNA guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue." [EC:2.7.7.50] synonym: "GTP--RNA guanylyltransferase activity" EXACT [EC:2.7.7.50] synonym: "GTP:mRNA guanylyltransferase activity" EXACT [] synonym: "messenger RNA guanylyltransferase activity" EXACT [EC:2.7.7.50] synonym: "mRNA capping enzyme activity" RELATED [EC:2.7.7.50] synonym: "protein lambda2" RELATED [EC:2.7.7.50] xref: EC:2.7.7.50 xref: GO:0004484 xref: MetaCyc:MRNA-GUANYLYLTRANSFERASE-RXN xref: Reactome:80327 is_a: CCO:F0001772 ! RNA guanylyltransferase activity [Term] id: CCO:F0000882 name: methylcrotonoyl-CoA carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 3-methylcrotonyl-CoA + HCO3- = ADP + phosphate + 3-methylglutaconyl-CoA." [EC:6.4.1.4] subset: gosubset_prok synonym: "3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.4] synonym: "beta-methylcrotonyl CoA carboxylase activity" EXACT [EC:6.4.1.4] synonym: "beta-methylcrotonyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.4] synonym: "beta-methylcrotonyl-CoA carboxylase activity" EXACT [EC:6.4.1.4] synonym: "methylcrotonyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.4] synonym: "methylcrotonyl-CoA carboxylase activity" EXACT [EC:6.4.1.4] xref: EC:6.4.1.4 xref: GO:0004485 xref: MetaCyc:METHYLCROTONYL-COA-CARBOXYLASE-RXN xref: Reactome:11585 is_a: CCO:F0003144 ! CoA carboxylase activity [Term] id: CCO:F0000883 name: methylenetetrahydrofolate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+." [EC:1.5.1.-, EC:1.5.1.15] subset: gosubset_prok synonym: "N5,N10-methylenetetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.5] xref: EC:1.5.1.- xref: GO:0004486 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000884 name: methylenetetrahydrofolate dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD+ = 5,10-methenyltetrahydrofolate + NADH + H+." [EC:1.5.1.15] synonym: "5,10-methylenetetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.5] synonym: "5,10-methylenetetrahydrofolate:NAD+ oxidoreductase" EXACT [EC:1.5.1.15] xref: EC:1.5.1.15 xref: GO:0004487 xref: MetaCyc:1.5.1.15-RXN is_a: CCO:F0000883 ! methylenetetrahydrofolate dehydrogenase activity [Term] id: CCO:F0000885 name: methylenetetrahydrofolate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH + H+." [EC:1.5.1.5] subset: gosubset_prok synonym: "5,10-methylenetetrahydrofolate:NADP oxidoreductase activity" EXACT [EC:1.5.1.5] synonym: "5,10-methylenetetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.5] xref: EC:1.5.1.5 xref: GO:0004488 xref: MetaCyc:METHYLENETHFDEHYDROG-NADP-RXN is_a: CCO:F0000883 ! methylenetetrahydrofolate dehydrogenase activity [Term] id: CCO:F0000886 name: methylenetetrahydrofolate reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+." [EC:1.5.1.20] comment: Includes EC 1.7.99.5. subset: gosubset_prok synonym: "1.7.99.5" RELATED [] synonym: "5,10-CH(2)-H(4)folate reductase activity" EXACT [EC:1.5.1.20] synonym: "5,10-CH2-H4folate reductase activity" EXACT [EC:1.5.1.20] synonym: "5,10-methylenetetrahydrofolate reductase (FADH(2)) activity" RELATED [EC:1.5.1.20] synonym: "5,10-methylenetetrahydrofolate reductase (FADH) activity" EXACT [] synonym: "5,10-methylenetetrahydrofolate reductase (FADH2) activity" EXACT [] synonym: "5,10-methylenetetrahydrofolate reductase (NADPH) activity" EXACT [EC:1.5.1.20] synonym: "5,10-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] synonym: "5,10-methylenetetrahydrofolic acid reductase activity" BROAD [EC:1.5.1.20] synonym: "5,10-methylenetetrahydropteroylglutamate reductase activity" EXACT [EC:1.5.1.20] synonym: "5-methyltetrahydrofolate:(acceptor) oxidoreductase activity" EXACT [EC:1.5.1.20] synonym: "5-methyltetrahydrofolate:NAD oxidoreductase activity" EXACT [EC:1.5.1.20] synonym: "5-methyltetrahydrofolate:NAD(+) oxidoreductase activity" EXACT [EC:1.5.1.20] synonym: "5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.5.1.20] synonym: "5-methyltetrahydrofolate:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.20] synonym: "5-methyltetrahydrofolate:NADP(+) oxidoreductase activity" EXACT [EC:1.5.1.20] synonym: "5-methyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.20] synonym: "MetF" RELATED [EC:1.5.1.20] synonym: "methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.5.1.20] synonym: "methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity" RELATED [EC:1.5.1.20] synonym: "methylenetetrahydrofolate reductase (NADPH(2)) activity" EXACT [EC:1.5.1.20] synonym: "methylenetetrahydrofolate reductase (NADPH2)" EXACT [EC:1.5.1.20] synonym: "methylenetetrahydrofolate reductase [NAD(P)H]" RELATED [EC:1.5.1.20] synonym: "methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] synonym: "methylenetetrahydrofolic acid reductase activity" BROAD [EC:1.5.1.20] synonym: "MTHFR activity" BROAD [EC:1.5.1.20] synonym: "N(5),N(10)-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] synonym: "N(5,10)-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.1.20] synonym: "N5,10-methylenetetrahydrofolate reductase activity" EXACT [EC:1.5.1.20] synonym: "N5,N10-methylenetetrahydrofolate reductase activity" EXACT [EC:1.5.1.20] xref: EC:1.5.1.20 xref: GO:0004489 xref: GO:0008702 xref: MetaCyc:1.5.1.20-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000887 name: methylglutaconyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H2O." [EC:4.2.1.18] subset: gosubset_prok synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)" EXACT [EC:4.2.1.18] synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity" EXACT [EC:4.2.1.18] synonym: "3-methylglutaconyl CoA hydratase activity" EXACT [EC:4.2.1.18] synonym: "methylglutaconase activity" EXACT [EC:4.2.1.18] synonym: "methylglutaconyl coenzyme A hydratase activity" EXACT [EC:4.2.1.18] xref: EC:4.2.1.18 xref: GO:0004490 xref: MetaCyc:METHYLGLUTACONYL-COA-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0000888 name: methylmalonate-semialdehyde dehydrogenase (acylating) activity namespace: molecular_function def: "Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+." [EC:1.2.1.27] subset: gosubset_prok synonym: "2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)" EXACT [EC:1.2.1.27] synonym: "MMSA dehydrogenase activity" EXACT [EC:1.2.1.27] synonym: "MSDH activity" EXACT [EC:1.2.1.27] xref: EC:1.2.1.27 xref: GO:0004491 xref: MetaCyc:1.2.1.27-RXN xref: Reactome:70889 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000889 name: methylmalonyl-CoA decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2." [EC:4.1.1.41] subset: gosubset_prok synonym: "(S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.41] synonym: "(S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)" EXACT [EC:4.1.1.41] synonym: "(S)-methylmalonyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.41] synonym: "methylmalonyl-coenzyme A decarboxylase activity" EXACT [EC:4.1.1.41] xref: EC:4.1.1.41 xref: GO:0004492 xref: MetaCyc:METHYLMALONYL-COA-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000890 name: methylmalonyl-CoA epimerase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-2-methyl-3-oxopropanoyl-CoA = (S)-2-methyl-3-oxopropanoyl-CoA." [EC:5.1.99.1] subset: gosubset_prok synonym: "2-methyl-3-oxopropanoyl-CoA 2-epimerase activity" EXACT [EC:5.1.99.1] synonym: "DL-methylmalonyl-CoA racemase activity" EXACT [EC:5.1.99.1] synonym: "dl-methylmalonyl-CoA racemase activity" EXACT [EC:5.1.99.1] synonym: "methylmalonyl coenzyme A racemase activity" EXACT [EC:5.1.99.1] synonym: "methylmalonyl-CoA 2-epimerase activity" EXACT [EC:5.1.99.1] synonym: "methylmalonyl-CoA racemase activity" EXACT [EC:5.1.99.1] xref: EC:5.1.99.1 xref: GO:0004493 xref: MetaCyc:METHYLMALONYL-COA-EPIM-RXN xref: Reactome:11610 is_a: CCO:F0003417 ! racemase and epimerase activity [Term] id: CCO:F0000891 name: methylmalonyl-CoA mutase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-2-methyl-3-oxopropanoyl-CoA = succinyl-CoA." [EC:5.4.99.2] subset: gosubset_prok synonym: "(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase activity" EXACT [EC:5.4.99.2] synonym: "(R)-methylmalonyl-CoA CoA-carbonylmutase activity" EXACT [EC:5.4.99.2] synonym: "(S)-methylmalonyl-CoA mutase activity" EXACT [EC:5.4.99.2] synonym: "methylmalonyl coenzyme A carbonylmutase activity" EXACT [EC:5.4.99.2] synonym: "methylmalonyl coenzyme A mutase activity" EXACT [EC:5.4.99.2] synonym: "methylmalonyl-CoA CoA-carbonyl mutase activity" EXACT [EC:5.4.99.2] xref: EC:5.4.99.2 xref: GO:0004494 xref: MetaCyc:METHYLMALONYL-COA-MUT-RXN xref: Reactome:11612 xref: UM-BBD_enzymeID:e0575 is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0000892 name: mevaldate reductase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor." [EC:1.1.1.32, EC:1.1.1.33] xref: EC:1.1.1.- xref: GO:0004495 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000893 name: mevalonate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate." [EC:2.7.1.36] subset: gosubset_prok synonym: "ATP:(R)-mevalonate 5-phosphotransferase activity" EXACT [EC:2.7.1.36] synonym: "ATP:mevalonate 5-phosphotransferase activity" EXACT [EC:2.7.1.36] synonym: "mevalonate 5-phosphotransferase activity" EXACT [EC:2.7.1.36] synonym: "mevalonate kinase (phosphorylating)" EXACT [EC:2.7.1.36] synonym: "mevalonate phosphokinase activity" EXACT [EC:2.7.1.36] synonym: "mevalonic acid kinase activity" EXACT [EC:2.7.1.36] synonym: "mevalonic kinase activity" EXACT [EC:2.7.1.36] synonym: "MVA kinase activity" EXACT [EC:2.7.1.36] xref: EC:2.7.1.36 xref: GO:0004496 xref: MetaCyc:MEVALONATE-KINASE-RXN xref: Reactome:11620 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000894 name: monooxygenase activity namespace: molecular_function def: "Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water." [http://www.onelook.com/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0004497 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0000895 name: calcidiol 1-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [EC:1.14.13.13] synonym: "1-hydroxylase-25-hydroxyvitamin D3" RELATED [EC:1.14.13.13] synonym: "25-hydroxy D3-1alpha-hydroxylase activity" EXACT [EC:1.14.13.13] synonym: "25-hydroxy vitamin D3 1-alpha-hydroxylase activity" EXACT [] synonym: "25-hydroxycholecalciferol 1-hydroxylase activity" EXACT [] synonym: "25-hydroxycholecalciferol 1-monooxygenase activity" EXACT [EC:1.14.13.13] synonym: "25-hydroxycholecalciferol 1alpha-hydroxylase activity" EXACT [EC:1.14.13.13] synonym: "25-hydroxycholecalciferol-1-hydroxylase activity" EXACT [EC:1.14.13.13] synonym: "25-hydroxyvitamin D-1 alpha hydroxylase activity" EXACT [EC:1.14.13.13] synonym: "25-hydroxyvitamin D3 1alpha-hydroxylase activity" EXACT [EC:1.14.13.13] synonym: "25-OHD-1 alpha-hydroxylase activity" EXACT [EC:1.14.13.13] synonym: "calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)" EXACT [EC:1.14.13.13] synonym: "cytochrome P450 CYP27B" NARROW [] xref: EC:1.14.13.13 xref: GO:0004498 xref: MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000896 name: flavin-containing monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O." [EC:1.14.13.8] subset: gosubset_prok synonym: "1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity" EXACT [EC:1.13.12.11] synonym: "dimethylaniline monooxygenase (N-oxide-forming) activity" EXACT [] synonym: "dimethylaniline N-oxidase activity" EXACT [EC:1.13.12.11] synonym: "dimethylaniline oxidase activity" EXACT [EC:1.13.12.11] synonym: "DMA oxidase activity" EXACT [EC:1.13.12.11] synonym: "FAD-containing monooxygenase activity" RELATED [EC:1.13.12.11] synonym: "flavin mixed function oxidase activity" RELATED [EC:1.13.12.11] synonym: "flavin monooxygenase activity" RELATED [EC:1.13.12.11] synonym: "FMO activity" RELATED [EC:1.13.12.11] synonym: "FMO-I" RELATED [EC:1.13.12.11] synonym: "FMO-II" RELATED [EC:1.13.12.11] synonym: "FMO1" RELATED [EC:1.13.12.11] synonym: "FMO2" RELATED [EC:1.13.12.11] synonym: "FMO3" RELATED [EC:1.13.12.11] synonym: "FMO4" RELATED [EC:1.13.12.11] synonym: "FMO5" RELATED [EC:1.13.12.11] synonym: "methylphenyltetrahydropyridine N-monooxygenase activity" EXACT [] synonym: "mixed-function amine oxidase activity" RELATED [EC:1.13.12.11] synonym: "N,N-dimethylaniline monooxygenase activity" EXACT [EC:1.13.12.11] synonym: "N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming)" EXACT [EC:1.13.12.11] synonym: "Ziegler's enzyme" RELATED [EC:1.13.12.11] xref: EC:1.14.13.8 xref: GO:0004499 xref: GO:0047076 xref: MetaCyc:1.14.13.8-RXN xref: Reactome:11625 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000897 name: dopamine beta-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxyphenethylamine + ascorbate + O2 = noradrenaline + dehydroascorbate + H2O." [EC:1.14.17.1] subset: gosubset_prok synonym: "(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity" EXACT [EC:1.14.17.1] synonym: "3,4-dihydroxyphenethylamine beta-oxidase activity" EXACT [EC:1.14.17.1] synonym: "3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)" EXACT [EC:1.14.17.1] synonym: "4-(2-aminoethyl)pyrocatechol beta-oxidase activity" EXACT [EC:1.14.17.1] synonym: "dopa beta-hydroxylase activity" EXACT [EC:1.14.17.1] synonym: "dopamine b-hydroxylase activity" EXACT [] synonym: "dopamine beta-hydroxylase activity" EXACT [EC:1.14.17.1] synonym: "dopamine beta-oxidase activity" EXACT [EC:1.14.17.1] synonym: "dopamine hydroxylase activity" EXACT [EC:1.14.17.1] synonym: "dopamine-B-hydroxylase activity" EXACT [EC:1.14.17.1] synonym: "MDBH (membrane-associated dopamine beta-monooxygenase)" RELATED [EC:1.14.17.1] synonym: "oxygenase, dopamine beta-mono-" EXACT [EC:1.14.17.1] synonym: "phenylamine beta-hydroxylase activity" EXACT [EC:1.14.17.1] synonym: "SDBH (soluble dopamine beta-monooxygenase)" RELATED [EC:1.14.17.1] xref: EC:1.14.17.1 xref: GO:0004500 xref: MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN is_a: CCO:F0003298 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000898 name: ecdysone 20-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: ecdysone + donor-H2 + O2 = 20-hydroxyecdysone + acceptor + H2O." [EC:1.14.99.22] synonym: "alpha-ecdysone C-20 hydroxylase activity" EXACT [EC:1.14.99.22] synonym: "ecdysone 20-hydroxylase activity" EXACT [] synonym: "ecdysone modification" BROAD [] synonym: "ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)" EXACT [EC:1.14.99.22] xref: EC:1.14.99.22 xref: GO:0004501 xref: MetaCyc:ECDYSONE-20-MONOOXYGENASE-RXN is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0000899 name: kynurenine 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-kynurenine + NADPH + H+ + O2 = 3-hydroxy-L-kynurenine + NADP+ + H2O." [EC:1.14.13.9] subset: gosubset_prok synonym: "kynurenine 3-hydroxylase activity" EXACT [] synonym: "kynurenine hydroxylase activity" EXACT [EC:1.14.13.9] synonym: "L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.9] synonym: "L-kynurenine-3-hydroxylase activity" EXACT [EC:1.14.13.9] xref: EC:1.14.13.9 xref: GO:0004502 xref: MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN xref: Reactome:12242 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000900 name: monophenol monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O." [EC:1.14.18.1] subset: gosubset_prok synonym: "catecholase" BROAD [EC:1.14.18.1] synonym: "chlorogenic acid oxidase activity" EXACT [EC:1.14.18.1] synonym: "chlorogenic oxidase activity" EXACT [EC:1.14.18.1] synonym: "cresolase activity" EXACT [EC:1.14.18.1] synonym: "dopa oxidase" BROAD [EC:1.14.18.1] synonym: "monophenol dihydroxyphenylalanine:oxygen oxidoreductase activity" EXACT [EC:1.14.18.1] synonym: "monophenol monooxidase activity" EXACT [EC:1.14.18.1] synonym: "monophenol oxidase activity" EXACT [EC:1.14.18.1] synonym: "monophenol oxygenase" EXACT [PMID:2494997] synonym: "monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase activity" EXACT [EC:1.14.18.1] synonym: "monophenol,L-dopa:oxygen oxidoreductase activity" EXACT [EC:1.14.18.1] synonym: "monophenolase activity" EXACT [EC:1.14.18.1] synonym: "N-acetyl-6-hydroxytryptophan oxidase activity" EXACT [EC:1.14.18.1] synonym: "o-diphenol oxidase activity" EXACT [EC:1.14.18.1] synonym: "o-diphenol oxidoreductase" BROAD [EC:1.14.18.1] synonym: "o-diphenol:O2 oxidoreductase activity" EXACT [EC:1.14.18.1] synonym: "o-diphenol:oxygen oxidoreductase" BROAD [EC:1.14.18.1] synonym: "phenol oxidase activity" EXACT [] synonym: "phenolase activity" BROAD [EC:1.14.18.1] synonym: "polyaromatic oxidase activity" EXACT [EC:1.14.18.1] synonym: "polyphenolase activity" EXACT [EC:1.14.18.1] synonym: "prophenol oxidase" RELATED [] synonym: "pyrocatechol oxidase" BROAD [EC:1.14.18.1] synonym: "tyrosinase activity" BROAD [EC:1.14.18.1] synonym: "tyrosine-dopa oxidase activity" EXACT [EC:1.14.18.1] xref: EC:1.14.18.1 xref: GO:0004503 xref: MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN is_a: CCO:F0003299 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000901 name: peptidylglycine monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O." [EC:1.14.17.3] subset: gosubset_prok synonym: "PAM activity" EXACT [EC:1.14.17.3] synonym: "PAM-A" RELATED [EC:1.14.17.3] synonym: "PAM-B" RELATED [EC:1.14.17.3] synonym: "peptide alpha-amidating enzyme" RELATED [EC:1.14.17.3] synonym: "peptide alpha-amide synthase activity" EXACT [EC:1.14.17.3] synonym: "peptide-alpha-amide synthetase activity" EXACT [EC:1.14.17.3] synonym: "peptidyl alpha-amidating enzyme activity" EXACT [EC:1.14.17.3] synonym: "peptidylglycine 2-hydroxylase activity" EXACT [] synonym: "peptidylglycine alpha-amidating monooxygenase activity" EXACT [EC:1.14.17.3] synonym: "peptidylglycine alpha-hydroxylase activity" EXACT [EC:1.14.17.3] synonym: "peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.17.3] synonym: "synthase, peptide alpha-amide" EXACT [EC:1.14.17.3] xref: EC:1.14.17.3 xref: GO:0004504 xref: MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN is_a: CCO:F0003298 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000902 name: phenylalanine 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin." [EC:1.14.16.1] subset: gosubset_prok synonym: "L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.16.1] synonym: "PAH activity" EXACT [EC:1.14.16.1] synonym: "phenylalaninase activity" EXACT [EC:1.14.16.1] synonym: "phenylalanine 4-hydroxylase activity" EXACT [EC:1.14.16.1] synonym: "phenylalanine hydroxylase activity" EXACT [] xref: EC:1.14.16.1 xref: GO:0004505 xref: MetaCyc:PHENYLALANINE-4-MONOOXYGENASE-RXN xref: Reactome:12249 is_a: CCO:F0003297 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000903 name: squalene monooxygenase activity namespace: molecular_function def: "Catalysis of the formation of a 2,3-epoxide in squalene." [EC:1.14.99.7] synonym: "squalene 2,3-oxidocyclase activity" EXACT [EC:1.14.99.7] synonym: "squalene epoxidase activity" EXACT [EC:1.14.99.7] synonym: "squalene hydroxylase activity" EXACT [] synonym: "squalene oxydocyclase activity" EXACT [EC:1.14.99.7] synonym: "squalene,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)" EXACT [EC:1.14.99.7] synonym: "squalene-2,3-epoxidase activity" EXACT [EC:1.14.99.7] synonym: "squalene-2,3-epoxide cyclase activity" EXACT [EC:1.14.99.7] xref: EC:1.14.99.7 xref: GO:0004506 xref: MetaCyc:SQUALENE-MONOOXYGENASE-RXN xref: Reactome:12251 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0000904 name: steroid 11-beta-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O." [EC:1.14.15.4] synonym: "cytochrome P450 CYP11B1" NARROW [] synonym: "cytochrome P450 CYP11B2" NARROW [] synonym: "cytochrome p450 XIB1 activity" NARROW [EC:1.14.15.4] synonym: "oxygenase, steroid 11beta -mono-" EXACT [EC:1.14.15.4] synonym: "steroid 11-beta-hydroxylase activity" EXACT [] synonym: "steroid 11-beta/18-hydroxylase activity" EXACT [EC:1.14.15.4] synonym: "steroid 11beta-hydroxylase activity" EXACT [EC:1.14.15.4] synonym: "steroid 11beta-monooxygenase activity" EXACT [EC:1.14.15.4] synonym: "steroid 11beta/18-hydroxylase activity" EXACT [EC:1.14.15.4] synonym: "steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)" EXACT [EC:1.14.15.4] xref: EC:1.14.15.4 xref: GO:0004507 xref: MetaCyc:STEROID-11-BETA-MONOOXYGENASE-RXN is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000905 name: steroid 17-alpha-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O." [EC:1.14.99.9] synonym: "17alpha-hydroxylase-C17,20 lyase activity" EXACT [EC:1.14.99.9] synonym: "cytochrome P-450 (P-45017alpha,lyase)" RELATED [EC:1.14.99.9] synonym: "cytochrome P450 CYP17" NARROW [] synonym: "cytochrome p450 XVIIA1 activity" NARROW [EC:1.14.99.9] synonym: "cytochrome P45017alpha" RELATED [EC:1.14.99.9] synonym: "steroid 17-alpha-hydroxylase activity" EXACT [] synonym: "steroid 17-alpha-hydroxylase-C17-20 lyase activity" EXACT [] synonym: "steroid 17-alpha-hydroxylase/17,20 lyase activity" EXACT [EC:1.14.99.9] synonym: "steroid 17alpha-hydroxylase activity" EXACT [EC:1.14.99.9] synonym: "steroid 17alpha-monooxygenase activity" EXACT [EC:1.14.99.9] synonym: "steroid 17alphahydroxylase/17,20 lyase activity" EXACT [EC:1.14.99.9] synonym: "steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)" EXACT [EC:1.14.99.9] xref: EC:1.14.99.9 xref: GO:0004508 xref: MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0000906 name: steroid 21-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O." [EC:1.14.99.10] synonym: "21-hydroxylase activity" EXACT [EC:1.14.99.10] synonym: "cytochrome P450 CYP21A1" NARROW [] synonym: "cytochrome p450 XXIA1 activity" NARROW [EC:1.14.99.10] synonym: "steroid 21-hydroxylase activity" EXACT [] synonym: "steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)" EXACT [EC:1.14.99.10] xref: EC:1.14.99.10 xref: GO:0004509 xref: MetaCyc:STEROID-21-MONOOXYGENASE-RXN is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0000907 name: tryptophan 5-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O." [EC:1.14.16.4] synonym: "indoleacetic acid-5-hydroxylase activity" EXACT [EC:1.14.16.4] synonym: "L-tryptophan hydroxylase activity" EXACT [] synonym: "L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.16.4] synonym: "tryptophan 5-hydroxylase activity" EXACT [EC:1.14.16.4] synonym: "tryptophan hydroxylase activity" EXACT [EC:1.14.16.4] xref: EC:1.14.16.4 xref: GO:0004510 xref: MetaCyc:TRYPTOPHAN-5-MONOOXYGENASE-RXN is_a: CCO:F0003297 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000908 name: tyrosine 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O." [EC:1.14.16.2] synonym: "L-tyrosine hydroxylase activity" EXACT [EC:1.14.16.2] synonym: "L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.16.2] synonym: "tyrosine 3-hydroxylase activity" EXACT [] synonym: "tyrosine hydroxylase activity" EXACT [] xref: EC:1.14.16.2 xref: GO:0004511 xref: MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN is_a: CCO:F0003297 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000909 name: inositol-3-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate; requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form." [EC:5.5.1.4] subset: gosubset_prok synonym: "1L-myo-inositol-1-phosphate lyase (isomerizing)" EXACT [EC:5.5.1.4] synonym: "D-glucose 6-phosphate cycloaldolase activity" EXACT [EC:5.5.1.4] synonym: "glucocycloaldolase activity" EXACT [EC:5.5.1.4] synonym: "glucose 6-phosphate cyclase activity" EXACT [EC:5.5.1.4] synonym: "glucose-6-phosphate inositol monophosphate cycloaldolase activity" EXACT [EC:5.5.1.4] synonym: "inositol 1-phosphate synthatase activity" EXACT [EC:5.5.1.4] synonym: "inositol 1-phosphate synthetase activity" EXACT [EC:5.5.1.4] synonym: "myo-inositol-1-phosphate synthase activity" EXACT [] xref: EC:5.5.1.4 xref: GO:0004512 xref: MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0000910 name: neolactotetraosylceramide alpha-2,3-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide." [EC:2.4.99.10] synonym: "CMP-N-acetylneuraminate:neolactotetraosylceramide alpha-2,3-sialyltransferase activity" EXACT [EC:2.4.99.10] synonym: "cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase activity" EXACT [EC:2.4.99.10] synonym: "SAT-3" RELATED [EC:2.4.99.10] synonym: "sialyltransferase 3" RELATED [EC:2.4.99.10] xref: EC:2.4.99.10 xref: GO:0004513 xref: MetaCyc:2.4.99.10-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0000911 name: nicotinate-nucleotide diphosphorylase (carboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.19] subset: gosubset_prok synonym: "NAD pyrophosphorylase activity" EXACT [EC:2.4.2.19] synonym: "nicotinate mononucleotide pyrophosphorylase (carboxylating)" EXACT [EC:2.4.2.19] synonym: "nicotinate-nucleotide pyrophosphorylase (carboxylating) activity" EXACT [] synonym: "nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)" EXACT [EC:2.4.2.19] synonym: "QAPRTase activity" EXACT [EC:2.4.2.19] synonym: "quinolinate phosphoribosyltransferase (decarboxylating) activity" EXACT [EC:2.4.2.19] synonym: "quinolinic acid phosphoribosyltransferase activity" EXACT [EC:2.4.2.19] synonym: "quinolinic phosphoribosyltransferase activity" EXACT [EC:2.4.2.19] xref: EC:2.4.2.19 xref: GO:0004514 xref: MetaCyc:QUINOPRIBOTRANS-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000912 name: nicotinate-nucleotide adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+." [EC:2.7.7.18] subset: gosubset_prok synonym: "ATP:nicotinate-nucleotide adenylyltransferase activity" EXACT [] synonym: "ATP:nicotinate-ribonucleotide adenylyltransferase activity" EXACT [EC:2.7.7.18] synonym: "deamido-NAD(+) diphosphorylase activity" EXACT [EC:2.7.7.18] synonym: "deamido-NAD(+) pyrophosphorylase activity" EXACT [EC:2.7.7.18] synonym: "deamido-NAD+ pyrophosphorylase activity" EXACT [EC:2.7.7.18] synonym: "deamidonicotinamide adenine dinucleotide pyrophosphorylase activity" EXACT [EC:2.7.7.18] synonym: "NaMN-ATase activity" EXACT [EC:2.7.7.18] synonym: "nicotinate mononucleotide adenylyltransferase activity" EXACT [EC:2.7.7.18] synonym: "nicotinic acid mononucleotide adenylyltransferase" NARROW [] xref: EC:2.7.7.18 xref: GO:0004515 xref: MetaCyc:NICONUCADENYLYLTRAN-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000913 name: nicotinate phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.11] subset: gosubset_prok synonym: "niacin ribonucleotidase activity" EXACT [EC:2.4.2.11] synonym: "nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.11] synonym: "nicotinic acid mononucleotide glycohydrolase activity" EXACT [EC:2.4.2.11] synonym: "nicotinic acid mononucleotide pyrophosphorylase activity" EXACT [EC:2.4.2.11] synonym: "nicotinic acid phosphoribosyltransferase activity" EXACT [EC:2.4.2.11] xref: EC:2.4.2.11 xref: GO:0004516 xref: MetaCyc:NICOTINATEPRIBOSYLTRANS-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000914 name: nitric-oxide synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+." [EC:1.14.13.39] subset: gosubset_prok synonym: "endothelium-derived relaxation factor-forming enzyme activity" RELATED [EC:1.14.13.39] synonym: "endothelium-derived relaxing factor synthase activity" RELATED [EC:1.14.13.39] synonym: "L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity" EXACT [EC:1.14.13.39] synonym: "NADPH-diaphorase activity" EXACT [EC:1.14.13.39] synonym: "nitric oxide synthase activity" EXACT [] synonym: "nitric oxide synthetase activity" EXACT [EC:1.14.13.39] synonym: "nitric-oxide synthetase activity" EXACT [EC:1.14.13.39] synonym: "NO synthase activity" EXACT [EC:1.14.13.39] xref: EC:1.14.13.39 xref: GO:0004517 xref: MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0000915 name: nuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids." [ISBN:0198547684] comment: Consider also annotating to the molecular function term 'nucleic acid binding ; GO:0003676'. subset: goslim_generic subset: goslim_plant subset: gosubset_prok xref: EC:3.1.-.- xref: GO:0004518 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0000916 name: endonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks." [GOC:mah, ISBN:0198547684] subset: gosubset_prok xref: GO:0004519 xref: Reactome:3138 is_a: CCO:F0000915 ! nuclease activity [Term] id: CCO:F0000917 name: endodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah, ISBN:0198547684] subset: gosubset_prok synonym: "endonuclease G activity" NARROW [] xref: GO:0004520 xref: Reactome:3136 is_a: CCO:F0000916 ! endonuclease activity is_a: CCO:F0000932 ! deoxyribonuclease activity [Term] id: CCO:F0000918 name: endoribonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:mah, ISBN:0198547684] subset: gosubset_prok synonym: "endonuclease G activity" NARROW [] xref: GO:0004521 is_a: CCO:F0000916 ! endonuclease activity is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0000919 name: pancreatic ribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates." [EC:3.1.27.5] synonym: "alkaline ribonuclease activity" EXACT [EC:3.1.27.5] synonym: "ceratitis capitata alkaline ribonuclease activity" EXACT [EC:3.1.27.5] synonym: "endoribonuclease I" RELATED [EC:3.1.27.5] synonym: "gene S glycoproteins" RELATED [EC:3.1.27.5] synonym: "gene S locus-specific glycoproteins" RELATED [EC:3.1.27.5] synonym: "pancreatic RNase activity" EXACT [EC:3.1.27.5] synonym: "ribonuclease A" EXACT [] synonym: "ribonuclease I activity" EXACT [EC:3.1.27.5] synonym: "ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity" EXACT [EC:3.1.27.5] synonym: "ribonucleic phosphatase activity" EXACT [EC:3.1.27.5] synonym: "RNase A activity" EXACT [EC:3.1.27.5] synonym: "RNase activity" BROAD [EC:3.1.27.5] synonym: "RNase I activity" EXACT [EC:3.1.27.5] synonym: "S-genotype-asssocd. glycoproteins" RELATED [EC:3.1.27.5] synonym: "SLSG glycoproteins" RELATED [EC:3.1.27.5] xref: EC:3.1.27.5 xref: GO:0004522 xref: MetaCyc:3.1.27.5-RXN is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0000920 name: ribonuclease H activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters." [EC:3.1.26.4] comment: Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species. subset: gosubset_prok synonym: "calf thymus ribonuclease H activity" EXACT [] synonym: "endoribonuclease H" RELATED [EC:3.1.26.4] synonym: "endoribonuclease H (calf thymus)" RELATED [EC:3.1.26.4] synonym: "endoribonuclease0 H activity" NARROW [EC:3.1.26.4] synonym: "hybrid nuclease activity" EXACT [EC:3.1.26.4] synonym: "hybrid ribonuclease activity" EXACT [EC:3.1.26.4] synonym: "hybridase (ribonuclease H)" EXACT [EC:3.1.26.4] synonym: "hybridase activity" EXACT [EC:3.1.26.4] synonym: "ribonuclease H1 activity" NARROW [] synonym: "ribonuclease H2 activity" NARROW [] synonym: "ribonuclease H3 activity" NARROW [] synonym: "RNA*DNA hybrid ribonucleotidohydrolase activity" EXACT [EC:3.1.26.4] synonym: "RNase H activity" EXACT [] synonym: "RNase H1 activity" NARROW [] synonym: "RNase H2 activity" NARROW [] synonym: "RNase H3 activity" NARROW [] xref: EC:3.1.26.4 xref: GO:0004523 xref: GO:0004524 xref: MetaCyc:3.1.26.4-RXN xref: Reactome:12321 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000921 name: ribonuclease III activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt." [PMID:11157775, PMID:15242644] subset: gosubset_prok synonym: "pre-mRNA 3'-end processing endonuclease" NARROW [] synonym: "ribonuclease 3 activity" EXACT [EC:3.1.26.3] synonym: "RNase III activity" EXACT [EC:3.1.26.3] xref: EC:3.1.26.3 xref: GO:0004525 xref: MetaCyc:3.1.26.3-RXN is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000922 name: ribonuclease P activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor." [EC:3.1.26.5] subset: gosubset_prok synonym: "RNase P" EXACT [] synonym: "tRNA 5' leader endonuclease activity" EXACT [] xref: EC:3.1.26.5 xref: GO:0004526 xref: MetaCyc:3.1.26.5-RXN is_a: CCO:F0000935 ! tRNA-specific ribonuclease activity is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000923 name: exonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end." [GOC:mah, ISBN:0198547684] subset: gosubset_prok xref: GO:0004527 is_a: CCO:F0000915 ! nuclease activity [Term] id: CCO:F0000924 name: phosphodiesterase I activity namespace: molecular_function def: "Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides." [EC:3.1.4.1] subset: gosubset_prok synonym: "5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [EC:3.1.4.1] synonym: "5'-exonuclease activity" RELATED [EC:3.1.4.1] synonym: "5'-NPDase activity" RELATED [EC:3.1.4.1] synonym: "5'-nucleotide phosphodiesterase activity" RELATED [EC:3.1.4.1] synonym: "5'-PDase activity" RELATED [EC:3.1.4.1] synonym: "5'-PDE activity" RELATED [EC:3.1.4.1] synonym: "5'-phosphodiesterase activity" RELATED [EC:3.1.4.1] synonym: "5'NPDE activity" RELATED [EC:3.1.4.1] synonym: "alkaline phosphodiesterase activity" RELATED [EC:3.1.4.1] synonym: "exonuclease I activity" RELATED [EC:3.1.4.1] synonym: "nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [EC:3.1.4.1] synonym: "oligonucleate 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.1] synonym: "orthophosphoric diester phosphohydrolase activity" EXACT [EC:3.1.4.1] synonym: "PDE I activity" EXACT [EC:3.1.4.1] synonym: "phosphodiesterase activity" BROAD [EC:3.1.4.1] xref: EC:3.1.4.1 xref: GO:0004528 xref: MetaCyc:3.1.4.1-RXN is_a: CCO:F0000923 ! exonuclease activity is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0000925 name: exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule." [GOC:mah, ISBN:0198547684] subset: gosubset_prok xref: GO:0004529 is_a: CCO:F0000923 ! exonuclease activity is_a: CCO:F0000932 ! deoxyribonuclease activity [Term] id: CCO:F0000926 name: deoxyribonuclease I activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products." [EC:3.1.21.1] subset: gosubset_prok synonym: "alkaline deoxyribonuclease activity" EXACT [EC:3.1.21.1] synonym: "alkaline DNase activity" EXACT [EC:3.1.21.1] synonym: "deoxyribonuclease (pancreatic)" NARROW [EC:3.1.21.1] synonym: "deoxyribonuclease A" RELATED [EC:3.1.21.1] synonym: "deoxyribonucleic phosphatase activity" EXACT [EC:3.1.21.1] synonym: "DNA depolymerase activity" EXACT [EC:3.1.21.1] synonym: "DNA endonuclease activity" EXACT [EC:3.1.21.1] synonym: "DNA nuclease activity" EXACT [EC:3.1.21.1] synonym: "DNAase activity" EXACT [EC:3.1.21.1] synonym: "DNase activity" NARROW [EC:3.1.21.1] synonym: "DNase I" RELATED [EC:3.1.21.1] synonym: "dornava" RELATED [EC:3.1.21.1] synonym: "dornavac" RELATED [EC:3.1.21.1] synonym: "endodeoxyribonuclease I" RELATED [EC:3.1.21.1] synonym: "Escherichia coli endonuclease I" RELATED [EC:3.1.21.1] synonym: "pancreatic deoxyribonuclease" NARROW [EC:3.1.21.1] synonym: "pancreatic DNase activity" NARROW [EC:3.1.21.1] synonym: "pancreatic dornase" NARROW [EC:3.1.21.1] synonym: "thymonuclease activity" NARROW [EC:3.1.21.1] synonym: "thymonuclease, dornase activity" EXACT [EC:3.1.21.1] xref: EC:3.1.21.1 xref: GO:0004530 xref: MetaCyc:3.1.21.1-RXN is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000927 name: deoxyribonuclease II activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products." [EC:3.1.22.1] subset: gosubset_prok synonym: "acid deoxyribonuclease activity" EXACT [EC:3.1.22.1] synonym: "acid DNase activity" EXACT [EC:3.1.22.1] synonym: "deoxyribonucleate 3'-nucleotidohydrolase activity" EXACT [EC:3.1.22.1] synonym: "DNase II activity" EXACT [EC:3.1.22.1] synonym: "lysosomal DNase II activity" NARROW [EC:3.1.22.1] synonym: "pancreatic DNase II" RELATED [EC:3.1.22.1] xref: EC:3.1.22.1 xref: GO:0004531 xref: MetaCyc:3.1.22.1-RXN is_a: CCO:F0003447 ! endodeoxyribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0000928 name: exoribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule." [GOC:mah, ISBN:0198547684] subset: gosubset_prok xref: GO:0004532 is_a: CCO:F0000923 ! exonuclease activity is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0000929 name: exoribonuclease H activity namespace: molecular_function def: "Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions." [EC:3.1.13.2, ISBN:0198547684] synonym: "retroviral reverse transcriptase RNaseH" RELATED [EC:3.1.13.2] xref: EC:3.1.13.2 xref: GO:0004533 xref: MetaCyc:3.1.13.2-RXN is_a: CCO:F0003454 ! exoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000930 name: 5'-3' exoribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule." [GOC:mah, ISBN:0198547684] xref: EC:3.1.13.- xref: GO:0004534 is_a: CCO:F0001876 ! 5'-3' exonuclease activity is_a: CCO:F0003454 ! exoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000931 name: poly(A)-specific ribonuclease activity namespace: molecular_function def: "Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP." [EC:3.1.13.4, ISBN:0198547684] synonym: "2',3'-exoribonuclease activity" EXACT [EC:3.1.13.4] synonym: "3'-exoribonuclease activity" EXACT [EC:3.1.13.4] synonym: "poly(A)-specific RNase activity" EXACT [] xref: EC:3.1.13.4 xref: GO:0004535 xref: MetaCyc:3.1.13.4-RXN is_a: CCO:F0003454 ! exoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0000932 name: deoxyribonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah, ISBN:0198547684] comment: Consider also annotating to the molecular function term 'DNA binding ; GO:0003677'. subset: gosubset_prok xref: GO:0004536 is_a: CCO:F0000915 ! nuclease activity [Term] id: CCO:F0000933 name: caspase-activated deoxyribonuclease activity namespace: molecular_function xref: GO:0004537 is_a: CCO:F0000932 ! deoxyribonuclease activity [Term] id: CCO:F0000934 name: ribonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:mah, ISBN:0198547684] comment: Consider also annotating to the molecular function term 'RNA binding ; GO:0003723'. subset: gosubset_prok xref: GO:0004540 is_a: CCO:F0000915 ! nuclease activity [Term] id: CCO:F0000935 name: tRNA-specific ribonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules." [GOC:mah] subset: gosubset_prok synonym: "tRNA-specific RNase activity" EXACT [] xref: GO:0004549 is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0000936 name: nucleoside diphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate." [EC:2.7.4.6] subset: gosubset_prok synonym: "ATP:nucleoside-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.6] synonym: "NDK activity" EXACT [EC:2.7.4.6] synonym: "nucleoside 5'-diphosphate kinase activity" EXACT [EC:2.7.4.6] synonym: "nucleoside 5'-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.6] synonym: "nucleoside diphosphate (UDP) kinase activity" EXACT [EC:2.7.4.6] synonym: "nucleoside diphosphokinase activity" EXACT [EC:2.7.4.6] synonym: "nucleoside-diphosphate kinase activity" EXACT [] synonym: "nucleotide phosphate kinase activity" EXACT [EC:2.7.4.6] synonym: "UDP kinase activity" EXACT [EC:2.7.4.6] synonym: "uridine diphosphate kinase activity" EXACT [EC:2.7.4.6] xref: EC:2.7.4.6 xref: GO:0004550 xref: MetaCyc:NUCLEOSIDE-DIP-KIN-RXN xref: Reactome:12403 is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0000937 name: nucleotide diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides." [EC:3.6.1.9] subset: gosubset_prok synonym: "dinucleotide nucleotidohydrolase activity" EXACT [EC:3.6.1.9] synonym: "nucleotide pyrophosphatase activity" EXACT [] synonym: "nucleotide-sugar pyrophosphatase activity" EXACT [EC:3.6.1.9] xref: EC:3.6.1.9 xref: GO:0004551 xref: MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0000938 name: octanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-octanol + NAD+ = 1-octanal + NADH + H+." [EC:1.1.1.73] synonym: "1-octanol dehydrogenase activity" EXACT [EC:1.1.1.73] synonym: "octanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.73] xref: EC:1.1.1.73 xref: GO:0004552 xref: MetaCyc:OCTANOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000939 name: hydrolase activity, hydrolyzing O-glycosyl compounds namespace: molecular_function def: "Catalysis of the hydrolysis of any O-glycosyl bond." [GOC:mah] subset: gosubset_prok synonym: "O-glucosyl hydrolase activity" EXACT [] xref: EC:3.2.1 xref: GO:0004553 is_a: CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds [Term] id: CCO:F0000940 name: alpha,alpha-trehalase activity namespace: molecular_function def: "Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose." [EC:3.2.1.28] subset: gosubset_prok synonym: "alpha,alpha-trehalose glucohydrolase activity" EXACT [EC:3.2.1.28] xref: EC:3.2.1.28 xref: GO:0004555 xref: MetaCyc:TREHALA-RXN xref: Reactome:12414 is_a: CCO:F0003022 ! trehalase activity [Term] id: CCO:F0000941 name: alpha-amylase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in polysaccharides containing three or more 1,4-alpha-linked D-glucose units." [EC:3.2.1.1] subset: gosubset_prok synonym: "1,4-alpha-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.1] synonym: "alpha amylase activity" EXACT [EC:3.2.1.1] synonym: "endoamylase activity" EXACT [EC:3.2.1.1] synonym: "glycogenase activity" BROAD [EC:3.2.1.1] synonym: "taka-amylase A" RELATED [EC:3.2.1.1] xref: EC:3.2.1.1 xref: GO:0004556 xref: MetaCyc:3.2.1.1-RXN xref: Reactome:12418 is_a: CCO:F0003051 ! amylase activity [Term] id: CCO:F0000942 name: alpha-galactosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase." [EC:3.2.1.22] subset: gosubset_prok synonym: "alpha-D-galactosidase activity" EXACT [EC:3.2.1.22] synonym: "alpha-D-galactoside galactohydrolase activity" EXACT [EC:3.2.1.22] synonym: "alpha-galactosidase A" RELATED [EC:3.2.1.22] synonym: "alpha-galactoside galactohydrolase activity" EXACT [EC:3.2.1.22] synonym: "melibiase activity" EXACT [] xref: EC:3.2.1.22 xref: GO:0004557 xref: MetaCyc:ALPHAGALACTOSID-RXN is_a: CCO:F0003020 ! galactosidase activity [Term] id: CCO:F0000943 name: alpha-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose." [EC:3.2.1.20] subset: gosubset_prok synonym: "acid maltase activity" EXACT [EC:3.2.1.20] synonym: "alpha-1,4-glucosidase activity" EXACT [EC:3.2.1.20] synonym: "alpha-D-glucosidase activity" EXACT [EC:3.2.1.20] synonym: "alpha-D-glucoside glucohydrolase activity" EXACT [EC:3.2.1.20] synonym: "alpha-glucopyranosidase activity" EXACT [EC:3.2.1.20] synonym: "alpha-glucosidase II" RELATED [] synonym: "alpha-glucoside hydrolase activity" EXACT [EC:3.2.1.20] synonym: "glucoinvertase activity" EXACT [EC:3.2.1.20] synonym: "glucosidoinvertase activity" EXACT [EC:3.2.1.20] synonym: "glucosidosucrase activity" EXACT [EC:3.2.1.20] synonym: "lysosomal alpha-glucosidase activity" BROAD [EC:3.2.1.20] synonym: "maltase-glucoamylase activity" EXACT [EC:3.2.1.20] xref: EC:3.2.1.20 xref: GO:0004558 xref: GO:0004562 xref: GO:0016982 xref: MetaCyc:3.2.1.20-RXN xref: Reactome:12426 is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0000944 name: alpha-mannosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides." [EC:3.2.1.24] subset: gosubset_prok synonym: "1,2-alpha-D-mannosidase activity" EXACT [EC:3.2.1.24] synonym: "1,2-alpha-mannosidase" BROAD [EC:3.2.1.24] synonym: "alpha-D-mannopyranosidase activity" EXACT [EC:3.2.1.24] synonym: "alpha-D-mannosidase activity" EXACT [EC:3.2.1.24] synonym: "alpha-D-mannoside mannohydrolase activity" EXACT [EC:3.2.1.24] synonym: "exo-alpha-mannosidase activity" EXACT [EC:3.2.1.24] synonym: "p-nitrophenyl-alpha-mannosidase activity" EXACT [EC:3.2.1.24] xref: EC:3.2.1.24 xref: GO:0004559 xref: MetaCyc:3.2.1.24-RXN is_a: CCO:F0003018 ! mannosidase activity [Term] id: CCO:F0000945 name: alpha-L-fucosidase activity namespace: molecular_function def: "Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose." [EC:3.2.1.51] subset: gosubset_prok synonym: "alpha-fucosidase activity" EXACT [EC:3.2.1.51] synonym: "alpha-L-fucoside fucohydrolase activity" EXACT [EC:3.2.1.51] xref: EC:3.2.1.51 xref: GO:0004560 xref: MetaCyc:ALPHA-L-FUCOSIDASE-RXN is_a: CCO:F0003023 ! fucosidase activity [Term] id: CCO:F0000946 name: alpha-N-acetylglucosaminidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides." [EC:3.2.1.50] synonym: "alpha-acetylglucosaminidase activity" EXACT [EC:3.2.1.50] synonym: "alpha-D-2-acetamido-2-deoxyglucosidase activity" EXACT [EC:3.2.1.50] synonym: "alpha-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase activity" EXACT [EC:3.2.1.50] synonym: "N-acetyl-alpha-D-glucosaminidase activity" EXACT [EC:3.2.1.50] synonym: "N-acetyl-alpha-glucosaminidase activity" EXACT [EC:3.2.1.50] synonym: "NAG activity" EXACT [EC:3.2.1.50] xref: EC:3.2.1.50 xref: GO:0004561 xref: MetaCyc:3.2.1.50-RXN is_a: CCO:F0003024 ! hexosaminidase activity [Term] id: CCO:F0000947 name: beta-N-acetylhexosaminidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides." [EC:3.2.1.52] subset: gosubset_prok synonym: "beta-acetylaminodeoxyhexosidase activity" EXACT [EC:3.2.1.52] synonym: "beta-acetylhexosaminidinase activity" EXACT [EC:3.2.1.52] synonym: "beta-D-hexosaminidase activity" EXACT [EC:3.2.1.52] synonym: "beta-D-N-acetylhexosaminidase activity" EXACT [EC:3.2.1.52] synonym: "beta-hexosaminidase activity" EXACT [EC:3.2.1.52] synonym: "beta-N-acetyl-D-hexosaminidase activity" EXACT [EC:3.2.1.52] synonym: "beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity" EXACT [EC:3.2.1.52] synonym: "hexosaminidase A" RELATED [EC:3.2.1.52] synonym: "N-acetyl-beta-D-hexosaminidase activity" EXACT [EC:3.2.1.52] synonym: "N-acetyl-beta-glucosaminidase activity" EXACT [EC:3.2.1.52] synonym: "N-acetyl-beta-hexosaminidase activity" EXACT [EC:3.2.1.52] synonym: "N-acetylhexosaminidase activity" EXACT [EC:3.2.1.52] xref: EC:3.2.1.52 xref: GO:0004563 xref: MetaCyc:3.2.1.52-RXN is_a: CCO:F0003024 ! hexosaminidase activity [Term] id: CCO:F0000948 name: beta-fructofuranosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides." [EC:3.2.1.26] subset: gosubset_prok synonym: "acid invertase activity" EXACT [] synonym: "alkaline invertase activity" EXACT [] synonym: "beta-D-fructofuranoside fructohydrolase activity" EXACT [] synonym: "beta-fructosidase activity" BROAD [] synonym: "beta-h-fructosidase activity" EXACT [] synonym: "fructosylinvertase activity" EXACT [] synonym: "glucosucrase activity" EXACT [] synonym: "invertase activity" BROAD [] synonym: "invertin activity" BROAD [] synonym: "maxinvert L 1000 activity" EXACT [] synonym: "saccharase activity" EXACT [] synonym: "sucrase activity" BROAD [] xref: EC:3.2.1.26 xref: GO:0004564 xref: MetaCyc:3.2.1.26-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0000949 name: beta-galactosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides." [EC:3.2.1.23] comment: Note that the inclusion of 'MetaCyc:BGALACT-PWY' is exceptional: normally MetaCyc pathway entries are database references for biological process terms, not molecular function terms. An exception was made in this case because the MetaCyc entry 'BGALACT-PWY' describes only one reaction, that catalyzed by beta-galactosidase. subset: gosubset_prok synonym: "beta-D-galactanase activity" EXACT [EC:3.2.1.23] synonym: "beta-D-galactoside galactohydrolase activity" EXACT [EC:3.2.1.23] synonym: "beta-D-lactosidase activity" EXACT [EC:3.2.1.23] synonym: "beta-lactosidase activity" EXACT [EC:3.2.1.23] synonym: "exo-(1->4)-beta-D-galactanase activity" EXACT [EC:3.2.1.23] synonym: "hydrolact" RELATED [EC:3.2.1.23] synonym: "lactose hydrolysis" RELATED [] synonym: "lactozym" RELATED [EC:3.2.1.23] synonym: "maxilact" RELATED [EC:3.2.1.23] synonym: "oryzatym" RELATED [EC:3.2.1.23] synonym: "S 2107" RELATED [EC:3.2.1.23] synonym: "sumiklat" RELATED [EC:3.2.1.23] synonym: "trilactase activity" EXACT [EC:3.2.1.23] xref: EC:3.2.1.23 xref: GO:0004565 xref: MetaCyc:3.2.1.23-RXN xref: MetaCyc:BGALACT-PWY is_a: CCO:F0003020 ! galactosidase activity [Term] id: CCO:F0000950 name: beta-glucuronidase activity namespace: molecular_function def: "Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate." [EC:3.2.1.31] subset: gosubset_prok synonym: "beta-D-glucuronoside glucuronosohydrolase activity" EXACT [EC:3.2.1.31] synonym: "beta-glucuronide glucuronohydrolase activity" EXACT [EC:3.2.1.31] synonym: "exo-beta-D-glucuronidase activity" EXACT [EC:3.2.1.31] synonym: "glucuronidase activity" EXACT [EC:3.2.1.31] synonym: "ketodase activity" EXACT [EC:3.2.1.31] xref: EC:3.2.1.31 xref: GO:0004566 xref: MetaCyc:BETA-GLUCURONID-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0000951 name: beta-mannosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides." [EC:3.2.1.25] subset: gosubset_prok synonym: "beta-D-mannosidase activity" EXACT [EC:3.2.1.25] synonym: "beta-D-mannoside mannohydrolase activity" EXACT [EC:3.2.1.25] synonym: "beta-mannoside mannohydrolase activity" EXACT [EC:3.2.1.25] synonym: "exo-beta-D-mannanase activity" EXACT [EC:3.2.1.25] synonym: "mannanase activity" EXACT [EC:3.2.1.25] synonym: "mannase activity" EXACT [EC:3.2.1.25] xref: EC:3.2.1.25 xref: GO:0004567 xref: MetaCyc:3.2.1.25-RXN is_a: CCO:F0003018 ! mannosidase activity [Term] id: CCO:F0000952 name: chitinase activity namespace: molecular_function def: "Catalysis of the random hydrolysis of N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins." [EC:3.2.1.14] subset: gosubset_prok synonym: "1,4-beta-poly-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.14] synonym: "beta-1,4-poly-N-acetyl glucosamidinase activity" EXACT [EC:3.2.1.14] synonym: "chitodextrinase activity" EXACT [EC:3.2.1.14] synonym: "poly-beta-glucosaminidase activity" EXACT [EC:3.2.1.14] synonym: "poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity" EXACT [EC:3.2.1.14] xref: EC:3.2.1.14 xref: GO:0004568 xref: MetaCyc:3.2.1.14-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0000953 name: glycoprotein endo-alpha-1,2-mannosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane." [EC:3.2.1.130] synonym: "endo-alpha-mannosidase activity" EXACT [EC:3.2.1.130] synonym: "endomannosidase activity" EXACT [EC:3.2.1.130] synonym: "glucosyl mannosidase activity" EXACT [EC:3.2.1.130] synonym: "glucosylmannosidase activity" EXACT [EC:3.2.1.130] synonym: "glycoprotein glucosylmannohydrolase activity" EXACT [EC:3.2.1.130] xref: EC:3.2.1.130 xref: GO:0004569 xref: MetaCyc:3.2.1.130-RXN is_a: CCO:F0000944 ! alpha-mannosidase activity [Term] id: CCO:F0000954 name: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2)." [EC:3.2.1.113] subset: gosubset_prok synonym: "1,2-alpha-mannosidase" BROAD [EC:3.2.1.113] synonym: "1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [EC:3.2.1.113] synonym: "exo-alpha-1,2-mannanase activity" EXACT [EC:3.2.1.113] synonym: "glycoprotein processing mannosidase I" RELATED [EC:3.2.1.113] synonym: "man9-mannosidase activity" RELATED [EC:3.2.1.113] synonym: "Man9-mannosidase activity" EXACT [EC:3.2.1.113] synonym: "ManI activity" NARROW [EC:3.2.1.113] synonym: "mannose-9 processing alpha-mannosidase activity" EXACT [EC:3.2.1.113] synonym: "mannosidase 1A activity" NARROW [EC:3.2.1.113] synonym: "mannosidase 1B activity" NARROW [EC:3.2.1.113] synonym: "mannosidase I" RELATED [EC:3.2.1.113] xref: EC:3.2.1.113 xref: GO:0004571 xref: MetaCyc:3.2.1.113-RXN is_a: CCO:F0003019 ! mannosyl-oligosaccharide mannosidase activity [Term] id: CCO:F0000955 name: mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the terminal 1,3- and 1,6-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3)." [EC:3.2.1.114] synonym: "1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [EC:3.2.1.114] synonym: "alpha-D-mannosidase II" RELATED [EC:3.2.1.114] synonym: "alpha-mannosidase II" RELATED [EC:3.2.1.114] synonym: "alpha1-3,6-mannosidase activity" EXACT [EC:3.2.1.114] synonym: "exo-1,3-1,6-alpha-mannosidase activity" EXACT [EC:3.2.1.114] synonym: "GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity" EXACT [EC:3.2.1.114] synonym: "golgi alpha-mannosidase II" RELATED [EC:3.2.1.114] synonym: "ManII activity" NARROW [EC:3.2.1.114] synonym: "mannosidase II activity" NARROW [EC:3.2.1.114] xref: EC:3.2.1.114 xref: GO:0004572 xref: MetaCyc:3.2.1.114-RXN is_a: CCO:F0003019 ! mannosyl-oligosaccharide mannosidase activity [Term] id: CCO:F0000956 name: mannosyl-oligosaccharide glucosidase activity namespace: molecular_function def: "Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2)." [EC:3.2.1.106] synonym: "Glc3Man9NAc2 oligosaccharide glucosidase activity" EXACT [EC:3.2.1.106] synonym: "mannosyl-oligosaccharide glucohydrolase activity" EXACT [EC:3.2.1.106] synonym: "mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity" EXACT [] synonym: "processing A-glucosidase I activity" RELATED [EC:3.2.1.106] synonym: "trimming glucosidase I" RELATED [EC:3.2.1.106] xref: EC:3.2.1.106 xref: GO:0004573 xref: MetaCyc:3.2.1.106-RXN is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0000957 name: oligo-1,6-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose." [EC:3.2.1.10] subset: gosubset_prok synonym: "alpha-limit dextrinase activity" EXACT [EC:3.2.1.10] synonym: "dextrin 6-glucanohydrolase activity" EXACT [EC:3.2.1.10] synonym: "dextrin 6alpha-glucanohydrolase activity" EXACT [EC:3.2.1.10] synonym: "exo-oligo-1,6-glucosidase activity" EXACT [EC:3.2.1.10] synonym: "isomaltase activity" RELATED [EC:3.2.1.10] synonym: "limit dextrinase (erroneous)" BROAD [EC:3.2.1.10] synonym: "oligosaccharide alpha-1,6-glucohydrolase activity" EXACT [EC:3.2.1.10] synonym: "oligosaccharide alpha-1,6-glucosidase activity" EXACT [EC:3.2.1.10] synonym: "sucrase-isomaltase activity" RELATED [EC:3.2.1.10] xref: EC:3.2.1.10 xref: GO:0004574 xref: MetaCyc:3.2.1.10-RXN is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0000958 name: sucrose alpha-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of sucrose and maltose by an alpha-D-glucosidase-type action." [EC:3.2.1.48] synonym: "intestinal sucrase activity" EXACT [EC:3.2.1.48] synonym: "sucrase activity" EXACT [EC:3.2.1.48] synonym: "sucrase(invertase)" RELATED [EC:3.2.1.48] synonym: "sucrase-isomaltase activity" EXACT [EC:3.2.1.48] synonym: "sucrose alpha-D-glucohydrolase activity" EXACT [] synonym: "sucrose alpha-glucohydrolase activity" EXACT [EC:3.2.1.48] synonym: "sucrose-alpha-D-glucohydrolase activity" EXACT [EC:3.2.1.48] synonym: "sucrose.alpha.-glucohydrolase activity" EXACT [EC:3.2.1.48] xref: EC:3.2.1.48 xref: GO:0004575 xref: MetaCyc:3.2.1.48-RXN xref: Reactome:12493 is_a: CCO:F0000943 ! alpha-glucosidase activity [Term] id: CCO:F0000959 name: oligosaccharyl transferase activity namespace: molecular_function def: "Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] subset: gosubset_prok xref: EC:2.4.1.- xref: GO:0004576 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0000960 name: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol." [EC:2.4.1.141] synonym: "N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity" EXACT [EC:2.4.1.141] synonym: "UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity" EXACT [EC:2.4.1.141] synonym: "UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.141] synonym: "uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.141] xref: EC:2.4.1.141 xref: GO:0004577 xref: MetaCyc:2.4.1.141-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0000961 name: chitobiosyldiphosphodolichol beta-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol." [EC:2.4.1.142] synonym: "GDP-mannose-dolichol diphosphochitobiose mannosyltransferase activity" EXACT [EC:2.4.1.142] synonym: "GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase activity" EXACT [EC:2.4.1.142] synonym: "guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase activity" EXACT [EC:2.4.1.142] xref: EC:2.4.1.142 xref: GO:0004578 xref: MetaCyc:2.4.1.142-RXN is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000962 name: dolichyl-diphosphooligosaccharide-protein glycotransferase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine." [EC:2.4.1.119] synonym: "asparagine N-glycosyltransferase activity" EXACT [EC:2.4.1.119] synonym: "dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity" EXACT [] synonym: "dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity" EXACT [EC:2.4.1.119] synonym: "dolichyldiphosphooligosaccharide-protein glycosyltransferase activity" EXACT [EC:2.4.1.119] synonym: "dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity" EXACT [EC:2.4.1.119] synonym: "dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity" EXACT [EC:2.4.1.119] synonym: "dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity" EXACT [EC:2.4.1.119] synonym: "oligomannosyltransferase activity" EXACT [EC:2.4.1.119] synonym: "oligosaccharide transferase activity" EXACT [EC:2.4.1.119] xref: EC:2.4.1.119 xref: GO:0004579 xref: MetaCyc:2.4.1.119-RXN is_a: CCO:F0000959 ! oligosaccharyl transferase activity [Term] id: CCO:F0000963 name: dolichyl-phosphate beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate." [EC:2.4.1.117] subset: gosubset_prok synonym: "polyprenyl phosphate:UDP-D-glucose glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "UDP-glucose dolichyl-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "UDP-glucose:dolichol phosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "UDP-glucose:dolicholphosphoryl glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "UDP-glucose:dolichyl monophosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "UDP-glucose:dolichyl phosphate glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.117] synonym: "uridine diphosphoglucose-dolichol glucosyltransferase activity" EXACT [EC:2.4.1.117] xref: EC:2.4.1.117 xref: GO:0004581 xref: MetaCyc:2.4.1.117-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0000964 name: dolichyl-phosphate beta-D-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate." [EC:2.4.1.83] subset: gosubset_prok synonym: "dolichol phosphate mannose synthase activity" EXACT [EC:2.4.1.83] synonym: "dolichol-phosphate mannose synthase activity" EXACT [EC:2.4.1.83] synonym: "dolichol-phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "dolichol-phosphate-mannose synthase activity" EXACT [] synonym: "dolichyl mannosyl phosphate synthase activity" EXACT [EC:2.4.1.83] synonym: "dolichyl phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "dolichyl-phosphate mannose synthase activity" EXACT [EC:2.4.1.83] synonym: "dolichyl-phospho-mannose synthase activity" EXACT [EC:2.4.1.83] synonym: "DPM synthase activity" EXACT [] synonym: "GDP-mannose-dolichol phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "GDPMan:DolP mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "GDPmannose-dolichylmonophosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "GDPmannose:dolichyl-phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "guanosine diphosphomannose-dolichol phosphate mannosyltransferase activity" EXACT [EC:2.4.1.83] synonym: "mannosylphosphodolichol synthase activity" EXACT [EC:2.4.1.83] synonym: "mannosylphosphoryldolichol synthase activity" EXACT [EC:2.4.1.83] xref: EC:2.4.1.83 xref: GO:0004582 xref: MetaCyc:2.4.1.83-RXN xref: Reactome:12521 is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000965 name: dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity namespace: molecular_function xref: EC:2.4.1.- xref: GO:0004583 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0000966 name: dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide." [EC:2.4.1.130] synonym: "dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase activity" EXACT [EC:2.4.1.130] synonym: "dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.130] synonym: "oligomannosylsynthase activity" EXACT [EC:2.4.1.130] xref: EC:2.4.1.130 xref: GO:0004584 xref: MetaCyc:2.4.1.130-RXN is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0000967 name: ornithine carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline." [EC:2.1.3.3] subset: gosubset_prok synonym: "carbamoyl-phosphate:L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.3] synonym: "carbamylphosphate-ornithine transcarbamylase activity" EXACT [EC:2.1.3.3] synonym: "citrulline phosphorylase activity" EXACT [EC:2.1.3.3] synonym: "L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.3] synonym: "L-ornithine carbamyltransferase activity" EXACT [EC:2.1.3.3] synonym: "L-ornithine transcarbamylase activity" EXACT [EC:2.1.3.3] synonym: "ornithine carbamyltransferase activity" EXACT [EC:2.1.3.3] synonym: "ornithine transcarbamylase activity" EXACT [EC:2.1.3.3] synonym: "OTC activity" EXACT [EC:2.1.3.3] synonym: "OTCase activity" EXACT [EC:2.1.3.3] xref: EC:2.1.3.3 xref: GO:0004585 xref: MetaCyc:ORNCARBAMTRANSFER-RXN xref: Reactome:12530 is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0000968 name: ornithine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-ornithine = putrescine + CO2." [EC:4.1.1.17] subset: gosubset_prok synonym: "L-ornithine carboxy-lyase (putrescine-forming)" EXACT [EC:4.1.1.17] synonym: "L-ornithine carboxy-lyase activity" NARROW [EC:4.1.1.17] synonym: "SpeC" RELATED [EC:4.1.1.17] xref: EC:4.1.1.17 xref: GO:0004586 xref: MetaCyc:ORNDECARBOX-RXN xref: Reactome:12531 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000969 name: ornithine-oxo-acid transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid." [EC:2.6.1.13] subset: gosubset_prok synonym: "GabT" RELATED [EC:2.6.1.13] synonym: "L-ornithine 5-aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "L-ornithine aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "L-ornithine:2-oxo-acid aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "L-ornithine:alpha-ketoglutarate delta-aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "OAT" RELATED [EC:2.6.1.13] synonym: "ornithine 5-aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine delta-transaminase activity" EXACT [EC:2.6.1.13] synonym: "ornithine ketoacid aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine transaminase activity" EXACT [EC:2.6.1.13] synonym: "ornithine--2-oxoacid aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine--alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine--keto acid aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine--keto acid transaminase activity" EXACT [EC:2.6.1.13] synonym: "ornithine--ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine--oxo acid aminotransferase activity" EXACT [EC:2.6.1.13] synonym: "ornithine--oxo-acid transaminase activity" EXACT [EC:2.6.1.13] synonym: "ornithine-oxo-acid aminotransferase activity" EXACT [] synonym: "ornithine:alpha-oxoglutarate transaminase activity" EXACT [EC:2.6.1.13] xref: EC:2.6.1.13 xref: GO:0004587 xref: MetaCyc:ORNITHINE--OXO-ACID-AMINOTRANSFERASE-RXN xref: Reactome:12532 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0000970 name: orotate phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.10] subset: gosubset_prok synonym: "OPRT activity" EXACT [EC:2.4.2.10] synonym: "OPRTase activity" EXACT [EC:2.4.2.10] synonym: "orotate phosphoribosyl pyrophosphate transferase activity" EXACT [EC:2.4.2.10] synonym: "orotic acid phosphoribosyltransferase activity" EXACT [EC:2.4.2.10] synonym: "orotidine 5'-monophosphate pyrophosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidine monophosphate pyrophosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidine phosphoribosyltransferase activity" EXACT [EC:2.4.2.10] synonym: "orotidine-5'-phosphate diphosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidine-5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity" EXACT [EC:2.4.2.10] synonym: "orotidylate phosphoribosyltransferase activity" EXACT [EC:2.4.2.10] synonym: "orotidylate pyrophosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidylic acid phosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidylic acid pyrophosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidylic phosphorylase activity" EXACT [EC:2.4.2.10] synonym: "orotidylic pyrophosphorylase activity" EXACT [EC:2.4.2.10] xref: EC:2.4.2.10 xref: GO:0004588 xref: MetaCyc:OROPRIBTRANS-RXN xref: Reactome:12534 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0000971 name: orotate reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-dihydroorotate + NAD+ = orotate + NADH + H+." [EC:1.3.1.14] synonym: "(S)-dihydroorotate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.14] xref: EC:1.3.1.14 xref: GO:0004589 xref: MetaCyc:OROTATE-REDUCTASE-(NADH)-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000972 name: orotidine-5'-phosphate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: orotidine 5'-phosphate = UMP + CO2." [EC:4.1.1.23] subset: gosubset_prok synonym: "ODCase activity" EXACT [EC:4.1.1.23] synonym: "OMP decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "OMP-DC" RELATED [EC:4.1.1.23] synonym: "OMPdcase activity" EXACT [EC:4.1.1.23] synonym: "orotate decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotate monophosphate decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotic decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotidine 5'-phosphate decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotidine monophosphate decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotidine phosphate decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotidine-5'-monophosphate decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotidine-5'-phosphate carboxy-lyase (UMP-forming)" EXACT [EC:4.1.1.23] synonym: "orotidine-5'-phosphate carboxy-lyase activity" EXACT [EC:4.1.1.23] synonym: "orotidylic acid decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotidylic decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "orotodylate decarboxylase activity" EXACT [EC:4.1.1.23] synonym: "UMP synthase activity" EXACT [EC:4.1.1.23] synonym: "uridine 5'-monophosphate synthase activity" EXACT [EC:4.1.1.23] xref: EC:4.1.1.23 xref: GO:0004590 xref: MetaCyc:OROTPDECARB-RXN xref: Reactome:12548 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000973 name: oxoglutarate dehydrogenase (succinyl-transferring) activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2." [EC:1.2.4.2] subset: gosubset_prok synonym: "2-ketoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] synonym: "2-oxoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] synonym: "2-oxoglutarate: lipoate oxidoreductase activity" EXACT [EC:1.2.4.2] synonym: "2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)" EXACT [EC:1.2.4.2] synonym: "2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity" EXACT [EC:1.2.4.2] synonym: "AKGDH activity" EXACT [EC:1.2.4.2] synonym: "alpha-ketoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] synonym: "alpha-ketoglutaric acid dehydrogenase activity" EXACT [EC:1.2.4.2] synonym: "alpha-ketoglutaric dehydrogenase activity" EXACT [EC:1.2.4.2] synonym: "alpha-oxoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] synonym: "ketoglutaric dehydrogenase activity" EXACT [EC:1.2.4.2] synonym: "OGDC activity" EXACT [EC:1.2.4.2] synonym: "oxoglutarate decarboxylase activity" EXACT [EC:1.2.4.2] synonym: "oxoglutarate dehydrogenase (lipoamide) activity" EXACT [] synonym: "oxoglutarate dehydrogenase activity" EXACT [EC:1.2.4.2] xref: EC:1.2.4.2 xref: GO:0004591 xref: MetaCyc:RXN0-1146 is_a: CCO:F0003226 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Term] id: CCO:F0000974 name: pantoate-beta-alanine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate." [EC:6.3.2.1] subset: gosubset_prok synonym: "(R)-pantoate:beta-alanine ligase (AMP-forming)" EXACT [EC:6.3.2.1] synonym: "D-pantoate:beta-alanine ligase (AMP-forming)" EXACT [EC:6.3.2.1] synonym: "pantoate-activating enzyme activity" RELATED [EC:6.3.2.1] synonym: "pantoic-activating enzyme activity" RELATED [EC:6.3.2.1] synonym: "pantothenate synthetase activity" EXACT [EC:6.3.2.1] xref: EC:6.3.2.1 xref: GO:0004592 xref: MetaCyc:PANTOATE-BETA-ALANINE-LIG-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0000975 name: pantothenase activity namespace: molecular_function def: "Catalysis of the reaction: pantothenate + H2O = pantoate + beta-alanine." [EC:3.5.1.22] synonym: "(R)-pantothenate amidohydrolase activity" EXACT [EC:3.5.1.22] synonym: "pantothenate amidohydrolase activity" EXACT [EC:3.5.1.22] synonym: "pantothenate hydrolase activity" EXACT [EC:3.5.1.22] xref: EC:3.5.1.22 xref: GO:0004593 xref: MetaCyc:PANTOTHENASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0000976 name: pantothenate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate." [EC:2.7.1.33] subset: gosubset_prok synonym: "ATP:(R)-pantothenate 4'-phosphotransferase activity" EXACT [EC:2.7.1.33] synonym: "ATP:pantothenate 4'-phosphotransferase activity" EXACT [EC:2.7.1.33] synonym: "D-pantothenate kinase activity" EXACT [EC:2.7.1.33] synonym: "pantothenate kinase (phosphorylating) activity" EXACT [EC:2.7.1.33] synonym: "pantothenic acid kinase activity" EXACT [EC:2.7.1.33] xref: EC:2.7.1.33 xref: GO:0004594 xref: MetaCyc:PANTOTHENATE-KIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0000977 name: pantetheine-phosphate adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pantetheine 4'-phosphate = diphosphate + dephospho-CoA." [EC:2.7.7.3] subset: gosubset_prok synonym: "3'-dephospho-CoA pyrophosphorylase activity" EXACT [EC:2.7.7.3] synonym: "ATP:pantetheine-4'-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.3] synonym: "ATP:pantetheine-phosphate adenylyltransferase activity" EXACT [] synonym: "dephospho-CoA diphosphorylase activity" EXACT [EC:2.7.7.3] synonym: "dephospho-CoA pyrophosphorylase activity" EXACT [EC:2.7.7.3] synonym: "dephospho-coenzyme A pyrophosphorylase activity" EXACT [EC:2.7.7.3] synonym: "pantetheine phosphate adenylyltransferase activity" EXACT [EC:2.7.7.3] synonym: "phosphopantetheine adenylyltransferase activity" EXACT [] synonym: "PPAT activity" EXACT [EC:2.7.7.3] xref: EC:2.7.7.3 xref: GO:0004595 xref: MetaCyc:PANTEPADENYLYLTRAN-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000978 name: peptide alpha-N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the acetylation of the N-terminal amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide." [EC:2.3.1.88, GOC:mah] subset: gosubset_prok synonym: "acetyl-CoA:peptide alpha-N-acetyltransferase activity" EXACT [EC:2.3.1.88] synonym: "acetyl-CoA:peptide nalpha-acetyltransferase activity" EXACT [EC:2.3.1.88] synonym: "amino-terminal amino acid-acetylating enzyme activity" RELATED [EC:2.3.1.88] synonym: "beta-endorphin acetyltransferase activity" NARROW [EC:2.3.1.88] synonym: "N(alpha)-acetyltransferase activity" RELATED [EC:2.3.1.88] synonym: "nalpha-acetyltransferase activity" EXACT [EC:2.3.1.88] synonym: "NAT activity" RELATED [EC:2.3.1.88] synonym: "peptide acetyltransferase activity" RELATED [EC:2.3.1.88] synonym: "protein N-terminal acetyltransferase activity" EXACT [EC:2.3.1.88] xref: EC:2.3.1.88 xref: GO:0004596 xref: MetaCyc:PEPTIDE-ALPHA-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0005533 ! peptide N-acetyltransferase activity [Term] id: CCO:F0000979 name: peptide-aspartate beta-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2." [EC:1.14.11.16] subset: gosubset_prok synonym: "aspartate beta-hydroxylase activity" EXACT [EC:1.14.11.16] synonym: "aspartyl/asparaginyl beta-hydroxylase activity" RELATED [EC:1.14.11.16] synonym: "aspartylpeptide beta-dioxygenase activity" EXACT [EC:1.14.11.16] synonym: "peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.16] xref: EC:1.14.11.16 xref: GO:0004597 xref: MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0000980 name: peptidylamidoglycolate lyase activity namespace: molecular_function def: "Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate." [EC:4.3.2.5] synonym: "alpha-hydroxyglycine amidating dealkylase activity" EXACT [EC:4.3.2.5] synonym: "HGAD" RELATED [EC:4.3.2.5] synonym: "PAL" RELATED [EC:4.3.2.5] synonym: "peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity" EXACT [EC:4.3.2.5] synonym: "peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming)" EXACT [EC:4.3.2.5] synonym: "peptidylamidoglycolate peptidylamide-lyase activity" EXACT [EC:4.3.2.5] synonym: "PGL" RELATED [EC:4.3.2.5] xref: EC:4.3.2.5 xref: GO:0004598 xref: MetaCyc:PEPTIDYLAMIDOGLYCOLATE-LYASE-RXN is_a: CCO:F0003407 ! amidine-lyase activity [Term] id: CCO:F0000981 name: peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: donor + H2O2 = oxidized donor + 2 H2O." [EC:1.11.1.7] subset: gosubset_prok synonym: "bacterial catalase-peroxidase activity" NARROW [] synonym: "donor:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.7] synonym: "eosinophil peroxidase activity" NARROW [] synonym: "extensin peroxidase" NARROW [EC:1.11.1.7] synonym: "guaiacol peroxidase" NARROW [EC:1.11.1.7] synonym: "heme peroxidase" NARROW [EC:1.11.1.7] synonym: "horseradish peroxidase (HRP)" NARROW [EC:1.11.1.7] synonym: "japanese radish peroxidase" NARROW [EC:1.11.1.7] synonym: "lactoperoxidase activity" NARROW [] synonym: "MPO" RELATED [EC:1.11.1.7] synonym: "myeloperoxidase activity" NARROW [] synonym: "oxyperoxidase activity" EXACT [EC:1.11.1.7] synonym: "peroxidase reaction" EXACT [] synonym: "protoheme peroxidase" NARROW [EC:1.11.1.7] synonym: "pyrocatechol peroxidase" NARROW [EC:1.11.1.7] synonym: "scopoletin peroxidase" NARROW [EC:1.11.1.7] synonym: "thiocyanate peroxidase" NARROW [EC:1.11.1.7] synonym: "verdoperoxidase" NARROW [EC:1.11.1.7] xref: EC:1.11.1.7 xref: GO:0004601 xref: GO:0016685 xref: GO:0016686 xref: GO:0016687 xref: MetaCyc:PEROXID-RXN xref: Reactome:4411 is_a: CCO:F0003069 ! antioxidant activity is_a: CCO:F0003274 ! oxidoreductase activity, acting on peroxide as acceptor [Term] id: CCO:F0000982 name: glutathione peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O." [EC:1.11.1.9] subset: gosubset_prok synonym: "glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.9] synonym: "GSH peroxidase activity" EXACT [EC:1.11.1.9] synonym: "non-selenium glutathione peroxidase activity" NARROW [] synonym: "reduced glutathione peroxidase activity" EXACT [EC:1.11.1.9] synonym: "selenium-glutathione peroxidase activity" EXACT [EC:1.11.1.9] xref: EC:1.11.1.9 xref: GO:0004602 xref: GO:0016224 xref: MetaCyc:GLUTATHIONE-PEROXIDASE-RXN xref: Reactome:13237 is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0000983 name: phenylethanolamine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine." [EC:2.1.1.28] synonym: "noradrenalin N-methyltransferase activity" EXACT [EC:2.1.1.28] synonym: "noradrenaline N-methyltransferase activity" RELATED [EC:2.1.1.28] synonym: "norepinephrine methyltransferase activity" EXACT [EC:2.1.1.28] synonym: "norepinephrine N-methyltransferase activity" EXACT [EC:2.1.1.28] synonym: "phenethanolamine methyltransferase activity" EXACT [EC:2.1.1.28] synonym: "phenethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.28] synonym: "S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.28] xref: EC:2.1.1.28 xref: GO:0004603 xref: MetaCyc:2.1.1.28-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0000984 name: phosphoadenylyl-sulfate reductase (thioredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenosine 5'-phosphosulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS." [EC:1.8.4.8] subset: gosubset_prok synonym: "3'-phosphoadenylylsulfate reductase activity" EXACT [EC:1.8.4.8] synonym: "adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.4.8] synonym: "adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.4.8] synonym: "PAdoPS reductase activity" EXACT [EC:1.8.4.8] synonym: "PAPS reductase activity" EXACT [EC:1.8.4.8] synonym: "PAPS reductase, thioredoxin-dependent activity" EXACT [EC:1.8.4.8] synonym: "PAPS sulfotransferase activity" EXACT [EC:1.8.4.8] synonym: "phosphoadenosine-phosphosulfate reductase activity" EXACT [EC:1.8.4.8] synonym: "phosphoadenylyl-sulphate reductase (thioredoxin) activity" EXACT [] synonym: "thioredoxin:3'-phospho-adenylylsulfate reductase activity" EXACT [EC:1.8.4.8] synonym: "thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity" EXACT [EC:1.8.4.8] xref: EC:1.8.4.8 xref: GO:0004604 xref: MetaCyc:1.8.4.8-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0000985 name: phosphatidate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol." [EC:2.7.7.41] subset: gosubset_prok synonym: "CDP diglyceride pyrophosphorylase activity" EXACT [EC:2.7.7.41] synonym: "CDP-DG" RELATED [EC:2.7.7.41] synonym: "CDP-diacylglyceride synthetase activity" EXACT [EC:2.7.7.41] synonym: "CDP-diacylglycerol synthase activity" EXACT [] synonym: "CDP-diglyceride diphosphorylase activity" EXACT [] synonym: "CDP-diglyceride pyrophosphorylase activity" EXACT [] synonym: "CDP-diglyceride synthase activity" EXACT [] synonym: "CDP-diglyceride synthetase activity" EXACT [EC:2.7.7.41] synonym: "CTP-diacylglycerol synthetase activity" EXACT [EC:2.7.7.41] synonym: "CTP:1,2-diacylglycerophosphate-cytidyl transferase activity" EXACT [EC:2.7.7.41] synonym: "CTP:phosphatidate cytidylyltransferase activity" EXACT [EC:2.7.7.41] synonym: "cytidine diphosphoglyceride pyrophosphorylase activity" EXACT [EC:2.7.7.41] synonym: "DAG synthetase activity" EXACT [EC:2.7.7.41] synonym: "phosphatidate cytidyltransferase activity" EXACT [EC:2.7.7.41] synonym: "phosphatidic acid cytidylyltransferase activity" EXACT [EC:2.7.7.41] xref: EC:2.7.7.41 xref: GO:0004605 xref: MetaCyc:CDPDIGLYSYN-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0000986 name: phosphatidylcholine-sterol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine." [EC:2.3.1.43] subset: gosubset_prok synonym: "LCAT (lecithin-cholesterol acyltransferase)" RELATED [EC:2.3.1.43] synonym: "LCAT activity" EXACT [EC:2.3.1.43] synonym: "lecithin--cholesterol acyltransferase activity" EXACT [EC:2.3.1.43] synonym: "lecithin:cholesterol acyltransferase activity" EXACT [EC:2.3.1.43] synonym: "phosphatidylcholine:sterol O-acyltransferase activity" EXACT [EC:2.3.1.43] synonym: "phospholipid--cholesterol acyltransferase activity" EXACT [EC:2.3.1.43] xref: EC:2.3.1.43 xref: GO:0004607 xref: MetaCyc:2.3.1.43-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0000987 name: phosphatidylethanolamine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine." [EC:2.1.1.17] subset: gosubset_prok synonym: "lipid methyl transferase activity" EXACT [EC:2.1.1.17] synonym: "LMTase activity" EXACT [EC:2.1.1.17] synonym: "PEMT" RELATED [EC:2.1.1.17] synonym: "phosphatidylethanolamine methyltransferase activity" EXACT [EC:2.1.1.17] synonym: "phosphatidylethanolamine-N-methylase activity" EXACT [EC:2.1.1.17] synonym: "phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity" EXACT [EC:2.1.1.17] synonym: "S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity" EXACT [EC:2.1.1.17] xref: EC:2.1.1.17 xref: GO:0004608 xref: MetaCyc:2.1.1.17-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0000988 name: phosphatidylserine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidyl-L-serine = phosphatidylethanolamine + CO2." [EC:4.1.1.65] subset: gosubset_prok synonym: "phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)" EXACT [EC:4.1.1.65] synonym: "phosphatidyl-L-serine carboxy-lyase activity" EXACT [EC:4.1.1.65] synonym: "PS decarboxylase activity" EXACT [EC:4.1.1.65] xref: EC:4.1.1.65 xref: GO:0004609 xref: MetaCyc:PHOSPHASERDECARB-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000989 name: phosphoacetylglucosamine mutase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate." [EC:5.4.2.3] subset: gosubset_prok synonym: "acetylaminodeoxyglucose phosphomutase activity" EXACT [EC:5.4.2.3] synonym: "acetylglucosamine phosphomutase activity" EXACT [EC:5.4.2.3] synonym: "N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.3] synonym: "N-acetyl-D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.3] synonym: "N-acetylglucosamine-phosphate mutase activity" EXACT [EC:5.4.2.3] synonym: "phospho-N-acetylglucosamine mutase activity" EXACT [EC:5.4.2.3] xref: EC:5.4.2.3 xref: GO:0004610 xref: MetaCyc:PHOSACETYLGLUCOSAMINEMUT-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0000990 name: phosphoenolpyruvate carboxykinase activity namespace: molecular_function def: "Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2." [EC:4.1.1.-] subset: gosubset_prok synonym: "PEP carboxykinase activity" EXACT [EC:4.1.1.-] synonym: "PEPCK activity" EXACT [EC:4.1.1.-] synonym: "phosphopyruvate carboxylase activity" EXACT [EC:4.1.1.-] xref: EC:4.1.1.- xref: GO:0004611 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0000991 name: phosphoenolpyruvate carboxykinase (ATP) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2." [EC:4.1.1.49] subset: gosubset_prok synonym: "ATP:oxaloacetate carboxy-lyase (transphosphorylating)" EXACT [EC:4.1.1.49] synonym: "ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.49] synonym: "PEPCK (ATP)" RELATED [EC:4.1.1.49] synonym: "PEPK" RELATED [EC:4.1.1.49] synonym: "phosphoenolpyruvate carboxylase (ATP)" EXACT [EC:4.1.1.49] synonym: "phosphoenolpyruvic carboxykinase" BROAD [EC:4.1.1.49] synonym: "phosphopyruvate carboxykinase" BROAD [EC:4.1.1.49] synonym: "phosphopyruvate carboxykinase (adenosine triphosphate)" EXACT [EC:4.1.1.49] synonym: "phosphopyruvate carboxylase (ATP)" EXACT [EC:4.1.1.49] xref: EC:4.1.1.49 xref: GO:0004612 xref: MetaCyc:PEPCARBOXYKIN-RXN is_a: CCO:F0000990 ! phosphoenolpyruvate carboxykinase activity [Term] id: CCO:F0000992 name: phosphoenolpyruvate carboxykinase (GTP) activity namespace: molecular_function def: "Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2." [EC:4.1.1.32] subset: gosubset_prok synonym: "GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.32] synonym: "GTP:oxaloacetate carboxy-lyase (transphosphorylating)" EXACT [EC:4.1.1.32] synonym: "phosphoenolpyruvate carboxylase (GTP)" EXACT [] synonym: "phosphoenolpyruvic carboxykinase" BROAD [EC:4.1.1.32] synonym: "phosphoenolpyruvic carboxykinase (GTP)" EXACT [EC:4.1.1.32] synonym: "phosphoenolpyruvic carboxylase (GTP)" EXACT [EC:4.1.1.32] synonym: "phosphopyruvate (guanosine triphosphate) carboxykinase activity" EXACT [EC:4.1.1.32] synonym: "phosphopyruvate carboxylase (GTP)" EXACT [EC:4.1.1.32] xref: EC:4.1.1.32 xref: GO:0004613 xref: MetaCyc:4.1.1.32-RXN xref: Reactome:13265 is_a: CCO:F0000990 ! phosphoenolpyruvate carboxykinase activity [Term] id: CCO:F0000993 name: phosphoglucomutase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate." [EC:5.4.2.2] subset: gosubset_prok synonym: "alpha-D-glucose 1,6-phosphomutase activity" EXACT [EC:5.4.2.2] synonym: "glucose phosphomutase activity" EXACT [EC:5.4.2.2] synonym: "phosphoglucose mutase activity" EXACT [EC:5.4.2.2] xref: EC:5.4.2.2 xref: GO:0004614 xref: MetaCyc:PHOSPHOGLUCMUT-RXN xref: Reactome:13266 is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0000994 name: phosphomannomutase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannose 1-phosphate = D-mannose 6-phosphate." [EC:5.4.2.8] subset: gosubset_prok synonym: "alpha-D-mannose 1,6-phosphomutase activity" EXACT [EC:5.4.2.8] synonym: "D-mannose 1,6-phosphomutase activity" EXACT [EC:5.4.2.8] synonym: "mannose phosphomutase activity" EXACT [EC:5.4.2.8] synonym: "phosphomannose mutase activity" EXACT [EC:5.4.2.8] xref: EC:5.4.2.8 xref: GO:0004615 xref: GO:0008971 xref: MetaCyc:PHOSMANMUT-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0000995 name: phosphogluconate dehydrogenase (decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+." [EC:1.1.1.44] subset: gosubset_prok synonym: "6-phospho-D-gluconate dehydrogenase activity" EXACT [EC:1.1.1.44] synonym: "6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.44] synonym: "6-phosphogluconate dehydrogenase (decarboxylating)" EXACT [EC:1.1.1.44] synonym: "6-phosphogluconic carboxylase activity" EXACT [EC:1.1.1.44] synonym: "6-phosphogluconic dehydrogenase activity" BROAD [EC:1.1.1.44] synonym: "6PGD activity" EXACT [EC:1.1.1.44] synonym: "phosphogluconic acid dehydrogenase activity" EXACT [EC:1.1.1.44] xref: EC:1.1.1.44 xref: GO:0004616 xref: MetaCyc:6PGLUCONDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000996 name: phosphoglycerate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+." [EC:1.1.1.95] subset: gosubset_prok synonym: "3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.95] synonym: "3-phosphoglycerate dehydrogenase activity" EXACT [EC:1.1.1.95] synonym: "3-phosphoglycerate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.95] synonym: "3-phosphoglyceric acid dehydrogenase activity" EXACT [EC:1.1.1.95] synonym: "3PHP reductase activity" EXACT [EC:1.1.1.95] synonym: "alpha-KG reductase activity" EXACT [EC:1.1.1.95] synonym: "alpha-phosphoglycerate dehydrogenase activity" EXACT [EC:1.1.1.95] synonym: "alphaKG reductase activity" EXACT [EC:1.1.1.95] synonym: "D- and L-HGA" RELATED [EC:1.1.1.95] synonym: "D-3-phosphoglycerate dehydrogenase activity" EXACT [EC:1.1.1.95] synonym: "D-3-phosphoglycerate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.95] synonym: "glycerate 3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.95] synonym: "glycerate-1,3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.95] synonym: "PGDH activity" EXACT [EC:1.1.1.95] synonym: "phosphoglycerate oxidoreductase activity" EXACT [EC:1.1.1.95] synonym: "phosphoglyceric acid dehydrogenase activity" EXACT [EC:1.1.1.95] synonym: "SerA" RELATED [EC:1.1.1.95] synonym: "SerA 3PG dehydrogenase activity" EXACT [EC:1.1.1.95] xref: EC:1.1.1.95 xref: GO:0004617 xref: MetaCyc:PGLYCDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0000997 name: phosphoglycerate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate." [EC:2.7.2.3] subset: gosubset_prok synonym: "3-PGK" RELATED [EC:2.7.2.3] synonym: "3-phosphoglycerate kinase activity" EXACT [EC:2.7.2.3] synonym: "3-phosphoglycerate phosphokinase activity" EXACT [EC:2.7.2.3] synonym: "3-phosphoglyceric acid kinase activity" EXACT [EC:2.7.2.3] synonym: "3-phosphoglyceric acid phosphokinase activity" EXACT [EC:2.7.2.3] synonym: "3-phosphoglyceric kinase activity" EXACT [EC:2.7.2.3] synonym: "ATP-3-phospho-D-glycerate-1-phosphotransferase activity" EXACT [EC:2.7.2.3] synonym: "ATP:3-phospho-D-glycerate 1-phosphotransferase activity" EXACT [EC:2.7.2.3] synonym: "ATP:D-3-phosphoglycerate 1-phosphotransferase activity" EXACT [EC:2.7.2.3] synonym: "glycerate 3-phosphate kinase activity" EXACT [EC:2.7.2.3] synonym: "glycerophosphate kinase activity" EXACT [EC:2.7.2.3] synonym: "PGK" RELATED [EC:2.7.2.3] synonym: "phosphoglyceric acid kinase activity" EXACT [EC:2.7.2.3] synonym: "phosphoglyceric kinase activity" EXACT [EC:2.7.2.3] synonym: "phosphoglycerokinase activity" EXACT [EC:2.7.2.3] xref: EC:2.7.2.3 xref: GO:0004618 xref: MetaCyc:PHOSGLYPHOS-RXN xref: Reactome:13282 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0000998 name: phosphoglycerate mutase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate." [EC:5.4.2.1] subset: gosubset_prok synonym: "bisphosphoglyceromutase" RELATED [EC:5.4.2.1] synonym: "D-phosphoglycerate 2,3-phosphomutase activity" EXACT [EC:5.4.2.1] synonym: "diphosphoglycomutase" RELATED [EC:5.4.2.1] synonym: "GriP mutase" NARROW [EC:5.4.2.1] synonym: "monophosphoglycerate mutase activity" EXACT [EC:5.4.2.1] synonym: "monophosphoglyceromutase activity" EXACT [EC:5.4.2.1] synonym: "MPGM" RELATED [EC:5.4.2.1] synonym: "PGA mutase activity" EXACT [EC:5.4.2.1] synonym: "PGAM activity" EXACT [EC:5.4.2.1] synonym: "PGM" EXACT [] synonym: "phosphoglycerate phosphomutase activity" EXACT [EC:5.4.2.1] synonym: "phosphoglyceromutase activity" EXACT [EC:5.4.2.1] xref: EC:5.4.2.1 xref: GO:0004619 xref: MetaCyc:3PGAREARR-RXN xref: Reactome:13285 is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0000999 name: phospholipase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a glycerophospholipid." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:3.1.1.- xref: GO:0004620 is_a: CCO:F0003111 ! lipase activity [Term] id: CCO:F0001000 name: glycosylphosphatidylinositol phospholipase D activity namespace: molecular_function def: "Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol." [EC:3.1.4.50] synonym: "glycoprotein phospholipase D activity" EXACT [] synonym: "glycoprotein-phosphatidylinositol phosphatidohydrolase activity" EXACT [EC:3.1.4.50] synonym: "GPI-PLD activity" EXACT [EC:3.1.4.50] synonym: "phosphatidylinositol phospholipase D activity" EXACT [EC:3.1.4.50] synonym: "phosphatidylinositol-glycan-specific phospholipase D activity" EXACT [EC:3.1.4.50] synonym: "phosphatidylinositol-specific phospholipase D activity" EXACT [EC:3.1.4.50] xref: EC:3.1.4.50 xref: GO:0004621 xref: MetaCyc:GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN is_a: CCO:F0001004 ! phospholipase D activity [Term] id: CCO:F0001001 name: lysophospholipase activity namespace: molecular_function def: "Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate." [EC:3.1.1.5] subset: gosubset_prok synonym: "2-lysophosphatidylcholine acylhydrolase activity" EXACT [EC:3.1.1.5] synonym: "lecithinase B activity" EXACT [EC:3.1.1.5] synonym: "lecitholipase activity" EXACT [EC:3.1.1.5] synonym: "lysolecithinase activity" EXACT [EC:3.1.1.5] synonym: "lysophopholipase L2" RELATED [EC:3.1.1.5] synonym: "lysophosphatidase activity" EXACT [EC:3.1.1.5] synonym: "lysophosphatidylcholine hydrolase activity" EXACT [EC:3.1.1.5] synonym: "lysophospholipase A1" RELATED [EC:3.1.1.5] synonym: "phosphatidase B" RELATED [EC:3.1.1.5] synonym: "phospholipase B activity" EXACT [EC:3.1.1.5] xref: EC:3.1.1.5 xref: GO:0004622 xref: GO:0045126 xref: MetaCyc:LYSOPHOSPHOLIPASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0000999 ! phospholipase activity [Term] id: CCO:F0001002 name: phospholipase A2 activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate." [EC:3.1.1.4] subset: gosubset_prok synonym: "cytosolic phospholipase A2 activity" NARROW [] synonym: "lecithinase A activity" EXACT [EC:3.1.1.4] synonym: "phosphatidase activity" RELATED [EC:3.1.1.4] synonym: "phosphatidolipase activity" EXACT [EC:3.1.1.4] synonym: "phosphatidylcholine 2-acylhydrolase activity" EXACT [EC:3.1.1.4] synonym: "phospholipase A" RELATED [EC:3.1.1.4] synonym: "secreted phospholipase A2 activity" NARROW [] xref: EC:3.1.1.4 xref: GO:0004623 xref: MetaCyc:PHOSPHOLIPASE-A2-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0000999 ! phospholipase activity [Term] id: CCO:F0001003 name: phospholipase C activity namespace: molecular_function def: "Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate." [EC:3.1.4.3, EC:3.1.4.4, GOC:mah] subset: gosubset_prok synonym: "lecithinase C activity" RELATED [EC:3.1.4.3] synonym: "lipophosphodiesterase C" RELATED [EC:3.1.4.3] synonym: "phosphatidase C" RELATED [EC:3.1.4.3] xref: GO:0004629 xref: GO:0042298 is_a: CCO:F0000999 ! phospholipase activity is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0001004 name: phospholipase D activity namespace: molecular_function def: "Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate." [EC:3.1.4.4] subset: gosubset_prok synonym: "choline phosphatase activity" EXACT [EC:3.1.4.4] synonym: "lecithinase D activity" EXACT [EC:3.1.4.4] synonym: "lipophosphodiesterase II activity" EXACT [EC:3.1.4.4] synonym: "phosphatidylcholine phosphatidohydrolase activity" EXACT [EC:3.1.4.4] xref: EC:3.1.4.4 xref: GO:0004630 xref: MetaCyc:PHOSPHOLIPASE-D-RXN is_a: CCO:F0000999 ! phospholipase activity is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0001005 name: phosphomevalonate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate." [EC:2.7.4.2] subset: gosubset_prok synonym: "5-phosphomevalonate kinase activity" EXACT [EC:2.7.4.2] synonym: "ATP:(R)-5-phosphomevalonate phosphotransferase activity" EXACT [EC:2.7.4.2] synonym: "ATP:5-phosphomevalonate phosphotransferase activity" EXACT [EC:2.7.4.2] synonym: "mevalonate phosphate kinase activity" EXACT [EC:2.7.4.2] synonym: "mevalonate-5-phosphate kinase activity" EXACT [EC:2.7.4.2] synonym: "mevalonic acid phosphate kinase activity" EXACT [EC:2.7.4.2] xref: EC:2.7.4.2 xref: GO:0004631 xref: MetaCyc:PHOSPHOMEVALONATE-KINASE-RXN xref: Reactome:13380 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0001006 name: phosphopantothenate--cysteine ligase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives." [EC:6.3.2.5] subset: gosubset_prok synonym: "(R)-4'-phosphopantothenate:L-cysteine ligase activity" EXACT [EC:6.3.2.5] synonym: "phosphopantothenate-cysteine ligase activity" EXACT [] synonym: "phosphopantothenoylcysteine synthetase activity" EXACT [] xref: EC:6.3.2.5 xref: GO:0004632 xref: MetaCyc:P-PANTOCYSLIG-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0001007 name: phosphopantothenoylcysteine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: N-((R)-4-phosphopantothenoyl)-L-cysteine = pantetheine 4'-phosphate + CO2." [EC:4.1.1.36] subset: gosubset_prok synonym: "4-phosphopantothenoyl-L-cysteine decarboxylase activity" EXACT [EC:4.1.1.36] synonym: "4-phosphopantotheoylcysteine decarboxylase activity" EXACT [EC:4.1.1.36] synonym: "N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.36] synonym: "N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)" EXACT [EC:4.1.1.36] synonym: "N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.36] synonym: "PPC-decarboxylase activity" EXACT [EC:4.1.1.36] xref: EC:4.1.1.36 xref: GO:0004633 xref: MetaCyc:P-PANTOCYSDECARB-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0001008 name: phosphopyruvate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O." [EC:4.2.1.11, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "14-3-2-protein" RELATED [EC:4.2.1.11] synonym: "2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)" EXACT [EC:4.2.1.11] synonym: "2-phospho-D-glycerate hydro-lyase activity" EXACT [EC:4.2.1.11] synonym: "2-phospho-D-glycerate-hydrolase activity" EXACT [] synonym: "2-phosphoglycerate dehydratase activity" EXACT [EC:4.2.1.11] synonym: "2-phosphoglycerate enolase activity" EXACT [EC:4.2.1.11] synonym: "2-phosphoglyceric dehydratase activity" EXACT [EC:4.2.1.11] synonym: "enolase activity" EXACT [EC:4.2.1.11] synonym: "gamma-enolase activity" EXACT [EC:4.2.1.11] synonym: "nervous-system specific enolase" NARROW [EC:4.2.1.11] synonym: "phosphoenolpyruvate hydratase activity" EXACT [EC:4.2.1.11] xref: EC:4.2.1.11 xref: GO:0004634 xref: MetaCyc:2PGADEHYDRAT-RXN xref: Reactome:13384 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001009 name: phosphoribosyl-AMP cyclohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 1-(5-phosphoribosyl)-AMP + H2O = 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide." [EC:3.5.4.19] subset: gosubset_prok synonym: "1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity" EXACT [EC:3.5.4.19] synonym: "phosphoribosyladenosine monophosphate cyclohydrolase activity" EXACT [EC:3.5.4.19] synonym: "PRAMP-cyclohydrolase activity" EXACT [EC:3.5.4.19] xref: EC:3.5.4.19 xref: GO:0004635 xref: MetaCyc:HISTCYCLOHYD-RXN is_a: CCO:F0004139 ! cyclohydrolase activity [Term] id: CCO:F0001010 name: phosphoribosyl-ATP diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 5-phosphoribosyl-ATP + H2O = 5-phosphoribosyl-AMP + diphosphate." [EC:3.6.1.31] subset: gosubset_prok synonym: "1-(5-phosphoribosyl)-ATP diphosphohydrolase activity" EXACT [EC:3.6.1.31] synonym: "phosphoribosyl-ATP pyrophosphatase activity" EXACT [] synonym: "phosphoribosyladenosine triphosphate pyrophosphatase activity" EXACT [EC:3.6.1.31] xref: EC:3.6.1.31 xref: GO:0004636 xref: MetaCyc:HISTPRATPHYD-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0001011 name: phosphoribosylamine-glycine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N1-(5-phospho-D-ribosyl)glycinamide." [EC:6.3.4.13] subset: gosubset_prok synonym: "2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity" EXACT [EC:6.3.4.13] synonym: "5'-phosphoribosylglycinamide synthetase activity" EXACT [EC:6.3.4.13] synonym: "5-phospho-D-ribosylamine:glycine ligase (ADP-forming)" EXACT [EC:6.3.4.13] synonym: "GAR" RELATED [EC:6.3.4.13] synonym: "GAR synthetase activity" EXACT [EC:6.3.4.13] synonym: "GARS activity" EXACT [EC:6.3.4.13] synonym: "glycinamide ribonucleotide synthetase activity" EXACT [EC:6.3.4.13] synonym: "glycineamide ribonucleotide synthetase activity" EXACT [EC:6.3.4.13] synonym: "phosphoribosylglycinamide synthetase activity" EXACT [EC:6.3.4.13] synonym: "phosphoribosylglycineamide synthetase activity" EXACT [EC:6.3.4.13] xref: EC:6.3.4.13 xref: GO:0004637 xref: MetaCyc:GLYRIBONUCSYN-RXN xref: Reactome:13392 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0001012 name: phosphoribosylaminoimidazole carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2." [EC:4.1.1.21] subset: gosubset_prok synonym: "1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity" EXACT [EC:4.1.1.21] synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]" RELATED [EC:4.1.1.21] synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity" EXACT [EC:4.1.1.21] synonym: "5-amino-1-ribosylimidazole 5-phosphate carboxylase activity" EXACT [EC:4.1.1.21] synonym: "5-phosphoribosyl-5-aminoimidazole carboxylase activity" EXACT [EC:4.1.1.21] synonym: "ADE2" RELATED [EC:4.1.1.21] synonym: "AIR carboxylase activity" EXACT [EC:4.1.1.21] synonym: "class II PurE" RELATED [EC:4.1.1.21] xref: EC:4.1.1.21 xref: GO:0004638 xref: MetaCyc:AIRCARBOXY-RXN xref: Reactome:13396 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0001013 name: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate." [EC:6.3.2.6] subset: gosubset_prok synonym: "4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.2.6] synonym: "4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity" EXACT [EC:6.3.2.6] synonym: "4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.2.6] synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)" EXACT [EC:6.3.2.6] synonym: "5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity" EXACT [EC:6.3.2.6] synonym: "phosphoribosylaminoimidazole-succinocarboxamide synthase activity" EXACT [EC:6.3.2.6] synonym: "phosphoribosylaminoimidazole-succinocarboxamide synthetase activity" EXACT [EC:6.3.2.6] synonym: "phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity" EXACT [EC:6.3.2.6] synonym: "PurC" RELATED [EC:6.3.2.6] synonym: "SAICAR synthase activity" EXACT [EC:6.3.2.6] synonym: "SAICAR synthetase activity" EXACT [EC:6.3.2.6] synonym: "SAICARs activity" EXACT [EC:6.3.2.6] xref: EC:6.3.2.6 xref: GO:0004639 xref: MetaCyc:SAICARSYN-RXN xref: Reactome:13398 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0001014 name: phosphoribosylanthranilate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)-anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate." [EC:5.3.1.24] subset: gosubset_prok synonym: "IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex)" RELATED [EC:5.3.1.24] synonym: "N-(5'-phosphoribosyl)anthranilate isomerase activity" EXACT [EC:5.3.1.24] synonym: "N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.24] synonym: "N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity" EXACT [EC:5.3.1.24] synonym: "PRA isomerase activity" EXACT [EC:5.3.1.24] synonym: "PRAI activity" EXACT [EC:5.3.1.24] xref: EC:5.3.1.24 xref: GO:0004640 xref: MetaCyc:PRAISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0001015 name: phosphoribosylformylglycinamidine cyclo-ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole." [EC:6.3.3.1] subset: gosubset_prok synonym: "2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.1] synonym: "2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.1] synonym: "5'-aminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.3.1] synonym: "AIR synthase activity" EXACT [EC:6.3.3.1] synonym: "AIR synthetase activity" EXACT [EC:6.3.3.1] synonym: "AIRS activity" EXACT [EC:6.3.3.1] synonym: "phosphoribosyl-aminoimidazole synthetase activity" EXACT [EC:6.3.3.1] synonym: "phosphoribosylaminoimidazole synthetase activity" EXACT [EC:6.3.3.1] xref: EC:6.3.3.1 xref: GO:0004641 xref: MetaCyc:AIRS-RXN xref: Reactome:13434 is_a: CCO:F0003441 ! cyclo-ligase activity [Term] id: CCO:F0001016 name: phosphoribosylformylglycinamidine synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5'-phosphoribosylformylglycinamide + L-glutamine + H2O = ADP + phosphate + 5'-phosphoribosylformylglycinamidine + L-glutamate." [EC:6.3.5.3] subset: gosubset_prok synonym: "2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3] synonym: "5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3] synonym: "FGAM synthase activity" EXACT [EC:6.3.5.3] synonym: "FGAM synthetase activity" EXACT [EC:6.3.5.3] synonym: "FGAR amidotransferase activity" EXACT [EC:6.3.5.3] synonym: "FGARAT activity" EXACT [EC:6.3.5.3] synonym: "formylglycinamide ribonucloetide amidotransferase activity" EXACT [EC:6.3.5.3] synonym: "formylglycinamide ribotide amidotransferase activity" EXACT [EC:6.3.5.3] synonym: "N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3] synonym: "phosphoribosylformylglycinamidine synthetase activity" EXACT [EC:6.3.5.3] synonym: "phosphoribosylformylglycineamidine synthetase activity" EXACT [EC:6.3.5.3] xref: EC:6.3.5.3 xref: GO:0004642 xref: MetaCyc:FGAMSYN-RXN xref: Reactome:13437 is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0001017 name: phosphoribosylaminoimidazolecarboxamide formyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide." [EC:2.1.2.3] subset: gosubset_prok synonym: "10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity" EXACT [EC:2.1.2.3] synonym: "10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity" EXACT [EC:2.1.2.3] synonym: "5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity" EXACT [EC:2.1.2.3] synonym: "5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity" EXACT [EC:2.1.2.3] synonym: "5-amino-4-imidazolecarboxamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.3] synonym: "5-amino-4-imidazolecarboxamide ribotide transformylase activity" EXACT [EC:2.1.2.3] synonym: "AICAR formyltransferase activity" EXACT [EC:2.1.2.3] synonym: "AICAR transformylase activity" EXACT [EC:2.1.2.3] synonym: "aminoimidazolecarboxamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.3] xref: EC:2.1.2.3 xref: GO:0004643 xref: MetaCyc:AICARTRANSFORM-RXN xref: Reactome:13439 is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0001018 name: phosphoribosylglycinamide formyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide." [EC:2.1.2.2] subset: gosubset_prok synonym: "10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase activity" EXACT [EC:2.1.2.2] synonym: "2-amino-N-ribosylacetamide 5'-phosphate transformylase activity" EXACT [EC:2.1.2.2] synonym: "5'-phosphoribosylglycinamide transformylase activity" EXACT [EC:2.1.2.2] synonym: "5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.2] synonym: "GAR formyltransferase activity" EXACT [EC:2.1.2.2] synonym: "GAR TFase activity" EXACT [EC:2.1.2.2] synonym: "GAR transformylase activity" EXACT [EC:2.1.2.2] synonym: "GART activity" EXACT [EC:2.1.2.2] synonym: "glycinamide ribonucleotide transformylase activity" EXACT [EC:2.1.2.2] xref: EC:2.1.2.2 xref: GO:0004644 xref: MetaCyc:GART-RXN xref: Reactome:13440 is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0001019 name: phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase." [EC:2.4.1.1] subset: gosubset_prok synonym: "1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.1] synonym: "1,4-alpha-glucan phosphorylase activity" EXACT [EC:2.4.1.1] synonym: "alpha-glucan phosphorylase" BROAD [EC:2.4.1.1] synonym: "amylopectin phosphorylase" NARROW [EC:2.4.1.1] synonym: "amylophosphorylase activity" NARROW [EC:2.4.1.1] synonym: "glucan phosphorylase" NARROW [EC:2.4.1.1] synonym: "glucosan phosphorylase" NARROW [EC:2.4.1.1] synonym: "granulose phosphorylase" NARROW [EC:2.4.1.1] synonym: "muscle phosphorylase" NARROW [EC:2.4.1.1] synonym: "muscle phosphorylase a and b activity" NARROW [EC:2.4.1.1] synonym: "myophosphorylase" NARROW [EC:2.4.1.1] synonym: "polyphosphorylase activity" EXACT [EC:2.4.1.1] synonym: "potato phosphorylase" NARROW [EC:2.4.1.1] synonym: "starch phosphorylase" NARROW [EC:2.4.1.1] xref: EC:2.4.1.1 xref: GO:0004645 xref: MetaCyc:RXN-1826 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0001020 name: phosphoserine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate." [EC:3.1.3.3] subset: gosubset_prok synonym: "O-phosphoserine phosphohydrolase activity" EXACT [EC:3.1.3.3] xref: EC:3.1.3.3 xref: GO:0004647 xref: MetaCyc:PSERPHOSPHA-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0001021 name: phosphoserine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate." [EC:2.6.1.52] subset: gosubset_prok synonym: "3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.52] synonym: "3-phosphoserine aminotransferase activity" EXACT [EC:2.6.1.52] synonym: "3PHP transaminase activity" EXACT [EC:2.6.1.52] synonym: "hydroxypyruvic phosphate--glutamic transaminase activity" EXACT [EC:2.6.1.52] synonym: "L-phosphoserine aminotransferase activity" EXACT [EC:2.6.1.52] synonym: "O-phospho-L-serine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.52] synonym: "PdxC" RELATED [EC:2.6.1.52] synonym: "phosphohydroxypyruvate transaminase activity" EXACT [EC:2.6.1.52] synonym: "phosphohydroxypyruvic--glutamic transaminase activity" EXACT [EC:2.6.1.52] synonym: "phosphoserine aminotransferase activity" EXACT [] synonym: "PSAT activity" EXACT [EC:2.6.1.52] synonym: "SerC" RELATED [EC:2.6.1.52] xref: EC:2.6.1.52 xref: GO:0004646 xref: GO:0004648 xref: MetaCyc:PSERTRANSAM-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0001022 name: poly(ADP-ribose) glycohydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose." [EC:3.2.1.143] xref: EC:3.2.1.143 xref: GO:0004649 xref: MetaCyc:3.2.1.143-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0001023 name: polygalacturonase activity namespace: molecular_function def: "Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans." [EC:3.2.1.15] subset: gosubset_prok synonym: "endo-D-galacturonase activity" EXACT [] synonym: "endo-polygalacturonase activity" EXACT [] synonym: "endogalacturonase activity" EXACT [] synonym: "endopolygalacturonase activity" EXACT [] synonym: "pectin depolymerase activity" NARROW [EC:3.2.1.15] synonym: "pectin hydrolase activity" EXACT [EC:3.2.1.15] synonym: "pectin polygalacturonase activity" EXACT [EC:3.2.1.15] synonym: "pectinase activity" NARROW [EC:3.2.1.15] synonym: "pectolase activity" EXACT [EC:3.2.1.15] synonym: "poly(1,4-alpha-D-galacturonide) glycanohydrolase activity" EXACT [] synonym: "poly-alpha-1,4-galacturonide glycanohydrolase activity" EXACT [] xref: EC:3.2.1.15 xref: GO:0004650 xref: MetaCyc:3.2.1.15-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0001024 name: polynucleotide 5'-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate." [EC:3.1.3.33] synonym: "5'-polynucleotidase activity" EXACT [EC:3.1.3.33] synonym: "polynucleotide 5'-phosphohydrolase activity" EXACT [EC:3.1.3.33] synonym: "polynucleotide 5'-triphosphatase activity" EXACT [EC:3.1.3.33] xref: EC:3.1.3.33 xref: GO:0004651 xref: MetaCyc:POLYNUCLEOTIDE-5 xref: Reactome:13463 is_a: CCO:F0004127 ! nucleotide phosphatase activity [Term] id: CCO:F0001025 name: polynucleotide adenylyltransferase activity namespace: molecular_function def: "Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group." [EC:2.7.7.19] subset: gosubset_prok synonym: "adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [EC:2.7.7.19] synonym: "AMP polynucleotidylexotransferase activity" EXACT [EC:2.7.7.19] synonym: "ATP-polynucleotide adenylyltransferase activity" EXACT [EC:2.7.7.19] synonym: "ATP:polynucleotide adenylyltransferase activity" EXACT [EC:2.7.7.19] synonym: "ATP:polynucleotidylexotransferase activity" EXACT [EC:2.7.7.19] synonym: "NTP polymerase activity" EXACT [EC:2.7.7.19] synonym: "poly(A) hydrolase activity" EXACT [EC:2.7.7.19] synonym: "poly(A) polymerase activity" EXACT [EC:2.7.7.19] synonym: "poly(A) synthetase activity" EXACT [EC:2.7.7.19] synonym: "poly-A polymerase activity" EXACT [EC:2.7.7.19] synonym: "polyadenylate nucleotidyltransferase activity" EXACT [EC:2.7.7.19] synonym: "polyadenylate polymerase activity" EXACT [EC:2.7.7.19] synonym: "polyadenylate synthetase activity" EXACT [EC:2.7.7.19] synonym: "polyadenylic acid polymerase activity" EXACT [EC:2.7.7.19] synonym: "polyadenylic polymerase activity" EXACT [EC:2.7.7.19] synonym: "RNA adenylating enzyme activity" EXACT [EC:2.7.7.19] synonym: "RNA formation factors, PF1" RELATED [EC:2.7.7.19] synonym: "terminal riboadenylate transferase activity" EXACT [EC:2.7.7.19] xref: EC:2.7.7.19 xref: GO:0004652 xref: MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN xref: Reactome:72182 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0001026 name: polypeptide N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. Catalyzes of the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis." [EC:2.4.1.41, ISBN:0879695595] synonym: "glycoprotein acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "polypeptide-N-acetylgalactosamine transferase activity" EXACT [EC:2.4.1.41] synonym: "protein-UDP acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] synonym: "UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity" EXACT [EC:2.4.1.41] synonym: "uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.41] xref: EC:2.4.1.41 xref: GO:0004653 xref: MetaCyc:2.4.1.41-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0001027 name: polyribonucleotide nucleotidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1)." [EC:2.7.7.8] subset: gosubset_prok synonym: "nucleoside diphosphate:polynucleotidyl transferase activity" EXACT [EC:2.7.7.8] synonym: "polynucleotide phosphorylase activity" EXACT [EC:2.7.7.8] synonym: "polyribonucleotide phosphorylase activity" EXACT [EC:2.7.7.8] synonym: "polyribonucleotide:phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.8] xref: EC:2.7.7.8 xref: GO:0004654 xref: MetaCyc:2.7.7.8-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0001028 name: porphobilinogen synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 5-aminolevulinate = porphobilinogen + 2 H2O." [EC:4.2.1.24] subset: gosubset_prok synonym: "5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)" EXACT [EC:4.2.1.24] synonym: "5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)" EXACT [EC:4.2.1.24] synonym: "5-levulinic acid dehydratase activity" EXACT [EC:4.2.1.24] synonym: "aminolevulinate dehydratase activity" EXACT [] synonym: "aminolevulinic dehydratase activity" EXACT [EC:4.2.1.24] synonym: "delta-aminolevulinate dehydratase activity" EXACT [EC:4.2.1.24] synonym: "delta-aminolevulinic acid dehydrase activity" EXACT [EC:4.2.1.24] synonym: "delta-aminolevulinic acid dehydratase activity" EXACT [] synonym: "delta-aminolevulinic dehydratase activity" EXACT [EC:4.2.1.24] xref: EC:4.2.1.24 xref: GO:0004655 xref: MetaCyc:PORPHOBILSYNTH-RXN xref: Reactome:13469 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001029 name: procollagen-proline 4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2." [EC:1.14.11.2] synonym: "collagen proline hydroxylase activity" EXACT [EC:1.14.11.2] synonym: "hydroxylase, collagen proline activity" EXACT [EC:1.14.11.2] synonym: "peptidyl proline hydroxylase activity" EXACT [EC:1.14.11.2] synonym: "procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity" EXACT [EC:1.14.11.2] synonym: "procollagen-proline,2-oxoglutarate-4-dioxygenase activity" EXACT [] synonym: "proline hydroxylase activity" BROAD [EC:1.14.11.2] synonym: "proline protocollagen hydroxylase activity" EXACT [EC:1.14.11.2] synonym: "proline, 2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.2] synonym: "proline,2-oxoglutarate 4-dioxygenase activity" BROAD [EC:1.14.11.2] synonym: "prolyl 4-hydroxylase activity" BROAD [EC:1.14.11.2] synonym: "prolyl hydroxylase activity" BROAD [EC:1.14.11.2] synonym: "prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity" EXACT [EC:1.14.11.2] synonym: "prolylprotocollagen dioxygenase activity" EXACT [EC:1.14.11.2] synonym: "prolylprotocollagen hydroxylase activity" EXACT [EC:1.14.11.2] synonym: "protocollagen hydroxylase activity" BROAD [EC:1.14.11.2] synonym: "protocollagen proline 4-hydroxylase activity" EXACT [EC:1.14.11.2] synonym: "protocollagen proline dioxygenase activity" EXACT [EC:1.14.11.2] synonym: "protocollagen proline hydroxylase activity" EXACT [EC:1.14.11.2] synonym: "protocollagen prolyl hydroxylase activity" EXACT [EC:1.14.11.2] xref: EC:1.14.11.2 xref: GO:0004656 xref: MetaCyc:1.14.11.2-RXN is_a: CCO:F0004175 ! procollagen-proline dioxygenase activity is_a: CCO:F0004684 ! peptidyl-proline 4-dioxygenase activity [Term] id: CCO:F0001030 name: proline dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor." [EC:1.5.99.8] subset: gosubset_prok synonym: "L-proline dehydrogenase activity" EXACT [EC:1.5.99.8] synonym: "L-proline:(acceptor) oxidoreductase activity" EXACT [EC:1.5.99.8] synonym: "L-proline:acceptor oxidoreductase activity" EXACT [EC:1.5.99.8] xref: EC:1.5.99.8 xref: GO:0004657 xref: MetaCyc:RXN-7181 xref: Reactome:13472 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0001031 name: propionyl-CoA carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA." [EC:6.4.1.3] subset: gosubset_prok synonym: "PCCase activity" EXACT [EC:6.4.1.3] synonym: "propanoyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.3] synonym: "propionyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.3] xref: EC:6.4.1.3 xref: GO:0004658 xref: MetaCyc:PROPIONYL-COA-CARBOXY-RXN xref: Reactome:13473 is_a: CCO:F0003144 ! CoA carboxylase activity [Term] id: CCO:F0001032 name: prenyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor)." [GOC:mah] subset: gosubset_prok xref: EC:2.5.1.- xref: GO:0004659 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0001033 name: protein farnesyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate." [EC:2.5.1.58, PMID:8621375] synonym: "CAAX farnesyltransferase activity" NARROW [EC:2.5.1.58] synonym: "farnesyl-diphosphate:protein-cysteine farnesyltransferase activity" EXACT [EC:2.5.1.58] synonym: "FTase activity" EXACT [EC:2.5.1.58] synonym: "protein-cysteine farnesyltransferase activity" EXACT [] xref: EC:2.5.1.58 xref: GO:0004660 xref: GO:0018223 is_a: CCO:F0001830 ! protein prenyltransferase activity [Term] id: CCO:F0001034 name: protein geranylgeranyltransferase activity namespace: molecular_function def: "Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein." [PMID:8621375] synonym: "protein-cysteine geranylgeranyltransferase activity" EXACT [] xref: EC:2.5.1.- xref: GO:0004661 xref: GO:0018224 is_a: CCO:F0001830 ! protein prenyltransferase activity [Term] id: CCO:F0001035 name: CAAX-protein geranylgeranyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families." [EC:2.5.1.59, PMID:8621375] synonym: "geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity" EXACT [] synonym: "geranylgeranyltransferase type I activity" EXACT [] synonym: "GGTase-I activity" EXACT [] synonym: "GGTaseI activity" EXACT [] synonym: "protein geranylgeranyltransferase type I" RELATED [EC:2.5.1.59] synonym: "type I protein geranyl-geranyltransferase activity" EXACT [EC:2.5.1.59] xref: EC:2.5.1.59 xref: GO:0004662 is_a: CCO:F0001034 ! protein geranylgeranyltransferase activity [Term] id: CCO:F0001036 name: Rab-protein geranylgeranyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family." [EC:2.5.1.60, GOC:mah, PMID:8621375] synonym: "geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity" EXACT [] synonym: "GGTase-II activity" EXACT [] synonym: "GGTaseII activity" EXACT [] synonym: "protein geranylgeranyltransferase type II activity" EXACT [] synonym: "Rab geranylgeranyltransferase activity" EXACT [] synonym: "RabGGTase activity" EXACT [] synonym: "type II protein geranyl-geranyltransferase activity" EXACT [EC:2.5.1.60] xref: EC:2.5.1.60 xref: GO:0004663 is_a: CCO:F0001034 ! protein geranylgeranyltransferase activity [Term] id: CCO:F0001037 name: prephenate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2." [EC:4.2.1.51] subset: gosubset_prok synonym: "prephenate hydro-lyase (decarboxylating)" EXACT [EC:4.2.1.51] synonym: "prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming)" EXACT [EC:4.2.1.51] xref: EC:4.2.1.51 xref: GO:0004664 xref: MetaCyc:PREPHENATEDEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001038 name: prephenate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH + H+." [EC:1.3.1.13] subset: gosubset_prok synonym: "prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.3.1.13] synonym: "prephenate:NADP+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.13] xref: EC:1.3.1.13 xref: GO:0004665 xref: MetaCyc:PREPHENATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001039 name: prostaglandin-endoperoxide synthase activity namespace: molecular_function def: "Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O." [EC:1.14.99.1] synonym: "(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.1] synonym: "(PG)H synthase activity" EXACT [EC:1.14.99.1] synonym: "fatty acid cyclooxygenase activity" EXACT [EC:1.14.99.1] synonym: "PG synthetase activity" EXACT [EC:1.14.99.1] synonym: "prostaglandin endoperoxide synthetase activity" EXACT [EC:1.14.99.1] synonym: "prostaglandin G/H synthase activity" EXACT [EC:1.14.99.1] synonym: "prostaglandin synthase activity" EXACT [EC:1.14.99.1] synonym: "prostaglandin synthetase activity" EXACT [EC:1.14.99.1] xref: EC:1.14.99.1 xref: GO:0004666 xref: MetaCyc:PROSTAGLANDIN-ENDOPEROXIDE-SYNTHASE-RXN xref: Reactome:13496 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001040 name: prostaglandin-D synthase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate." [EC:5.3.99.2] synonym: "(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity" EXACT [EC:5.3.99.2] synonym: "PGD2 synthase activity" EXACT [EC:5.3.99.2] synonym: "PGH-PGD isomerase activity" EXACT [EC:5.3.99.2] synonym: "prostaglandin D2 synthase activity" EXACT [EC:5.3.99.2] synonym: "prostaglandin-H2 D-isomerase activity" EXACT [EC:5.3.99.2] synonym: "prostaglandin-R-prostaglandin D isomerase activity" EXACT [EC:5.3.99.2] xref: EC:5.3.99.2 xref: GO:0004667 xref: MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0001041 name: protein-arginine deiminase activity namespace: molecular_function def: "Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3." [EC:3.5.3.15] subset: gosubset_prok synonym: "peptidylarginine deiminase activity" EXACT [EC:3.5.3.15] synonym: "protein-L-arginine iminohydrolase activity" EXACT [EC:3.5.3.15] xref: EC:3.5.3.15 xref: GO:0004668 xref: MetaCyc:PROTEIN-ARGININE-DEIMINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0001042 name: protein-S-isoprenylcysteine O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester." [EC:2.1.1.100] subset: gosubset_prok synonym: "farnesyl cysteine C-terminal methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "farnesyl-protein carboxymethyltransferase activity" EXACT [EC:2.1.1.100] synonym: "farnesylated protein C-terminal O-methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "isoprenylated protein methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "isoprenylcysteine carboxylmethyltransferase activity" RELATED [EC:2.1.1.100] synonym: "prenylated protein carboxyl methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "prenylated protein methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "prenylcysteine carboxyl methyltransferase activity" RELATED [EC:2.1.1.100] synonym: "prenylcysteine carboxylmethyltransferase activity" EXACT [EC:2.1.1.100] synonym: "prenylcysteine carboxymethyltransferase activity" EXACT [EC:2.1.1.100] synonym: "prenylcysteine methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "protein C-terminal farnesylcysteine O-methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "protein S-farnesylcysteine C-terminal methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity" EXACT [EC:2.1.1.100] synonym: "S-farnesylcysteine methyltransferase activity" EXACT [EC:2.1.1.100] xref: EC:2.1.1.100 xref: GO:0004671 xref: GO:0018225 xref: MetaCyc:2.1.1.100-RXN is_a: CCO:F0000399 ! C-terminal protein carboxyl methyltransferase activity is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001043 name: protein kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP." [MetaCyc:PROTEIN-KINASE-RXN] comment: Note that triphosphate is used as a phosphate donor by at least one kinase. subset: goslim_candida subset: goslim_generic subset: goslim_yeast subset: gosubset_prok synonym: "protamine kinase activity" NARROW [] xref: GO:0004672 xref: GO:0050222 xref: MetaCyc:PROTEIN-KINASE-RXN xref: Reactome:4030 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0001044 name: protein histidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine." [EC:2.7.13.3, GOC:mah] subset: gosubset_prok synonym: "ATP:protein-L-histidine N-phosphotransferase activity" EXACT [EC:2.7.13.3] synonym: "EnvZ" NARROW [EC:2.7.13.3] synonym: "histidine kinase (ambiguous)" EXACT [EC:2.7.13.3] synonym: "histidine kinase activity" EXACT [] synonym: "histidine protein kinase (ambiguous)" EXACT [EC:2.7.13.3] synonym: "histidine protein kinase activity" EXACT [EC:2.7.13.3] synonym: "HK1" RELATED [EC:2.7.13.3] synonym: "HP165" RELATED [EC:2.7.13.3] synonym: "protein histidine kinase (ambiguous)" EXACT [EC:2.7.13.3] synonym: "protein kinase (histidine)" EXACT [EC:2.7.13.3] synonym: "protein kinase (histidine) (ambiguous)" EXACT [EC:2.7.13.3] synonym: "protein-histidine kinase activity" EXACT [] synonym: "Sln1p" NARROW [EC:2.7.13.3] xref: EC:2.7.13.3 xref: GO:0004673 xref: GO:0008896 is_a: CCO:F0001043 ! protein kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0001045 name: protein serine/threonine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate." [GOC:bf] subset: gosubset_prok synonym: "A-kinase activity" NARROW [EC:2.7.11.1] synonym: "AP50 kinase activity" NARROW [EC:2.7.11.1] synonym: "ATP-protein transphosphorylase activity" NARROW [EC:2.7.11.1] synonym: "ATP:protein phosphotransferase (non-specific) activity" NARROW [EC:2.7.11.1] synonym: "betaIIPKC" RELATED [EC:2.7.11.1] synonym: "calcium/phospholipid-dependent protein kinase activity" NARROW [EC:2.7.11.1] synonym: "casein kinase (phosphorylating) activity" NARROW [EC:2.7.11.1] synonym: "cytidine 3',5'-cyclic monophosphate-responsive protein kinase activity" NARROW [EC:2.7.11.1] synonym: "dsk1" RELATED [EC:2.7.11.1] synonym: "epsilon PKC" RELATED [EC:2.7.11.1] synonym: "glycogen synthase a kinase activity" NARROW [EC:2.7.11.1] synonym: "glycogen synthase A kinase activity" NARROW [EC:2.7.11.1] synonym: "glycogen synthase kinase activity" NARROW [EC:2.7.11.1] synonym: "HIPK2" RELATED [EC:2.7.11.1] synonym: "Hpr kinase activity" NARROW [EC:2.7.11.1] synonym: "hydroxyalkyl-protein kinase activity" NARROW [EC:2.7.11.1] synonym: "M phase-specific cdc2 kinase activity" NARROW [EC:2.7.11.1] synonym: "MAPK" RELATED [EC:2.7.11.1] synonym: "mitogen-activated protein kinase activity" BROAD [EC:2.7.11.1] synonym: "mitogen-activated S6 kinase activity" NARROW [EC:2.7.11.1] synonym: "non-specific serine/threonine protein kinase activity" NARROW [EC:2.7.11.1] synonym: "p82 kinase activity" NARROW [EC:2.7.11.1] synonym: "phosphorylase B kinase kinase activity" NARROW [EC:2.7.11.1] synonym: "phosphorylase b kinase kinase activity" BROAD [EC:2.7.11.1] synonym: "PKA" RELATED [EC:2.7.11.1] synonym: "PKC" RELATED [EC:2.7.11.1] synonym: "protein glutamyl kinase activity" NARROW [EC:2.7.11.1] synonym: "protein kinase (phosphorylating) activity" NARROW [EC:2.7.11.1] synonym: "protein kinase A activity" BROAD [EC:2.7.11.1] synonym: "protein kinase p58 activity" NARROW [EC:2.7.11.1] synonym: "protein phosphokinase activity" NARROW [EC:2.7.11.1] synonym: "protein serine kinase activity" NARROW [EC:2.7.11.1] synonym: "protein serine-threonine kinase activity" EXACT [EC:2.7.11.1] synonym: "protein-aspartyl kinase activity" RELATED [EC:2.7.11.1] synonym: "protein-cysteine kinase activity" NARROW [EC:2.7.11.1] synonym: "protein-serine kinase activity" NARROW [EC:2.7.11.1] synonym: "Prp4 protein kinase activity" NARROW [EC:2.7.11.1] synonym: "Raf kinase activity" NARROW [EC:2.7.11.1] synonym: "Raf-1" RELATED [EC:2.7.11.1] synonym: "ribosomal protein S6 kinase II activity" NARROW [EC:2.7.11.1] synonym: "ribosomal S6 protein kinase activity" NARROW [EC:2.7.11.1] synonym: "serine kinase activity" NARROW [EC:2.7.11.1] synonym: "serine protein kinase activity" NARROW [EC:2.7.11.1] synonym: "serine(threonine) protein kinase activity" EXACT [EC:2.7.11.1] synonym: "serine-specific protein kinase activity" NARROW [EC:2.7.11.1] synonym: "serine/threonine protein kinase activity" EXACT [EC:2.7.11.1] synonym: "STK32" RELATED [EC:2.7.11.1] synonym: "T-antigen kinase activity" NARROW [EC:2.7.11.1] synonym: "threonine-specific protein kinase activity" NARROW [EC:2.7.11.1] synonym: "twitchin kinase activity" NARROW [EC:2.7.11.1] synonym: "Wee 1-like kinase activity" NARROW [EC:2.7.11.1] synonym: "Wee-kinase activity" NARROW [EC:2.7.11.1] synonym: "WEE1Hu" RELATED [EC:2.7.11.1] xref: EC:2.7.11 xref: GO:0004674 xref: Reactome:4028 is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0001046 name: transmembrane receptor protein serine/threonine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + receptor-protein serine/threonine = ADP + receptor-protein serine/threonine phosphate." [EC:2.7.11.30] synonym: "activin receptor kinase activity" NARROW [EC:2.7.11.30] synonym: "ATP:receptor-protein phosphotransferase activity" EXACT [EC:2.7.11.30] synonym: "receptor protein serine/threonine kinase activity" EXACT [EC:2.7.11.30] synonym: "receptor serine/threonine protein kinase activity" EXACT [EC:2.7.11.30] synonym: "receptor type I serine/threonine protein kinase activity" NARROW [EC:2.7.11.30] synonym: "receptor type II serine/threonine protein kinase activity" NARROW [EC:2.7.11.30] synonym: "STK13" RELATED [EC:2.7.11.30] synonym: "TGF-beta kinase activity" NARROW [EC:2.7.11.30] xref: EC:2.7.11.- xref: GO:0004675 xref: Reactome:11160 is_a: CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity is_a: CCO:F0004122 ! transmembrane receptor protein kinase activity [Term] id: CCO:F0001047 name: 3-phosphoinositide-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a 3-phosphoinositide." [GOC:mah] xref: EC:2.7.11.- xref: GO:0004676 xref: Reactome:13519 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001048 name: DNA-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, requiring the presence of DNA." [GOC:mah] xref: EC:2.7.11.- xref: GO:0004677 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001049 name: AMP-activated protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of AMP." [GOC:mah] synonym: "5'-AMP-activated protein kinase activity" EXACT [] synonym: "SNF1A/AMP-activated protein kinase activity" NARROW [] xref: EC:2.7.11.- xref: GO:0004679 xref: Reactome:13522 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001050 name: casein kinase activity namespace: molecular_function xref: EC:2.7.11.- xref: GO:0004680 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001051 name: casein kinase I activity namespace: molecular_function xref: EC:2.7.11.- xref: GO:0004681 is_a: CCO:F0001050 ! casein kinase activity [Term] id: CCO:F0001052 name: protein kinase CK2 activity namespace: molecular_function def: "Catalysis of the reaction: casein + ATP = phosphocasein + ADP." [EC:2.7.11.1] synonym: "casein kinase II activity" RELATED [] synonym: "casein kinase II, catalytic activity" EXACT [] synonym: "protein kinase CK2, intrinsic catalyst activity" EXACT [] xref: GO:0004682 xref: GO:0008604 is_a: CCO:F0001050 ! casein kinase activity [Term] id: CCO:F0001053 name: calmodulin-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium-bound calmodulin." [GOC:mah, PMID:11264466] subset: gosubset_prok synonym: "ATP:caldesmon O-phosphotransferase activity" NARROW [EC:2.7.11.17] synonym: "ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity" EXACT [EC:2.7.11.17] synonym: "Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity" NARROW [EC:2.7.11.17] synonym: "Ca2+/calmodulin-dependent protein kinase 1 activity" NARROW [EC:2.7.11.17] synonym: "Ca2+/calmodulin-dependent protein kinase activity" EXACT [EC:2.7.11.17] synonym: "Ca2+/calmodulin-dependent protein kinase II activity" NARROW [EC:2.7.11.17] synonym: "Ca2+/calmodulin-dependent protein kinase IV activity" NARROW [EC:2.7.11.17] synonym: "Ca2+/calmodulin-dependent protein kinase kinase activity" NARROW [EC:2.7.11.17] synonym: "Ca2+/calmodulin-dependent protein kinase kinase beta activity" NARROW [EC:2.7.11.17] synonym: "Ca2+/CaM-dependent kinase activity" EXACT [] synonym: "calcium- and calmodulin-dependent protein kinase activity" EXACT [] synonym: "calcium/calmodulin-dependent protein kinase activity" EXACT [EC:2.7.11.17] synonym: "calcium/calmodulin-dependent protein kinase type II activity" NARROW [EC:2.7.11.17] synonym: "caldesmon kinase (phosphorylating) activity" NARROW [EC:2.7.11.17] synonym: "calmodulin regulated protein kinase activity" EXACT [] synonym: "calmodulin-dependent kinase II activity" NARROW [EC:2.7.11.17] synonym: "calmodulin-dependent protein kinase I activity" NARROW [] synonym: "CaM kinase activity" EXACT [EC:2.7.11.17] synonym: "CaM kinase II activity" NARROW [EC:2.7.11.17] synonym: "CAM PKII" RELATED [EC:2.7.11.17] synonym: "CaM-regulated serine/threonine kinase activity" EXACT [EC:2.7.11.17] synonym: "CaMKI" RELATED [EC:2.7.11.17] synonym: "CaMKII" RELATED [EC:2.7.11.17] synonym: "CaMKIV" RELATED [EC:2.7.11.17] synonym: "CaMKKalpha" RELATED [EC:2.7.11.17] synonym: "CaMKKbeta" RELATED [EC:2.7.11.17] synonym: "microtubule-associated protein 2 kinase activity" RELATED [EC:2.7.11.17] synonym: "multifunctional calcium- and calmodulin-regulated protein kinase activity" RELATED [] synonym: "multifunctional calcium/calmodulin regulated protein kinase activity" RELATED [] synonym: "STK20" RELATED [EC:2.7.11.17] xref: EC:2.7.11.17 xref: GO:0004683 xref: GO:0004684 xref: GO:0004685 xref: GO:0004688 xref: MetaCyc:2.7.11.17-RXN is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001054 name: elongation factor-2 kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of eukaryotic elongation factor-2." [GOC:jl, PMID:11904175] synonym: "ATP:elongation factor 2 phosphotransferase activity" EXACT [EC:2.7.11.20] synonym: "Ca/CaM-kinase III activity" EXACT [EC:2.7.11.20] synonym: "calmodulin-dependent protein kinase III activity" EXACT [EC:2.7.11.20] synonym: "CaM kinase III activity" EXACT [EC:2.7.11.20] synonym: "eEF-2 kinase activity" EXACT [] synonym: "eEF2 kinase activity" EXACT [EC:2.7.11.20] synonym: "eEF2K" RELATED [EC:2.7.11.20] synonym: "EF2K" RELATED [EC:2.7.11.20] synonym: "elongation factor 2 kinase activity" EXACT [EC:2.7.11.20] synonym: "eukaryotic elongation factor 2 kinase activity" EXACT [EC:2.7.11.20] synonym: "STK19" RELATED [EC:2.7.11.20] xref: EC:2.7.11.20 xref: GO:0004686 is_a: CCO:F0001053 ! calmodulin-dependent protein kinase activity [Term] id: CCO:F0001055 name: myosin light chain kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (myosin-light-chain) = ADP + (myosin-light-chain) phosphate." [EC:2.7.11.18] synonym: "ATP:myosin-light-chain O-phosphotransferase" BROAD [EC:2.7.11.18] synonym: "ATP:myosin-light-chain O-phosphotransferase activity" EXACT [EC:2.7.11.18] synonym: "calcium/calmodulin-dependent myosin light chain kinase activity" EXACT [EC:2.7.11.18] synonym: "MLCK" RELATED [EC:2.7.11.18] synonym: "MLCkase activity" EXACT [EC:2.7.11.18] synonym: "myosin kinase activity" EXACT [EC:2.7.11.18] synonym: "myosin light chain protein kinase activity" EXACT [EC:2.7.11.18] synonym: "myosin light-chain kinase" BROAD [EC:2.7.11.18] synonym: "myosin light-chain kinase (phosphorylating)" EXACT [EC:2.7.11.18] synonym: "myosin light-chain kinase (phosphorylating) activity" EXACT [EC:2.7.11.18] synonym: "myosin light-chain kinase activity" EXACT [EC:2.7.11.18] synonym: "myosin-light-chain kinase activity" EXACT [] synonym: "smooth-muscle-myosin-light-chain kinase activity" NARROW [EC:2.7.11.18] synonym: "STK18" RELATED [EC:2.7.11.18] xref: EC:2.7.11.18 xref: GO:0004687 xref: MetaCyc:MYOSIN-LIGHT-CHAIN-KINASE-RXN is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001056 name: phosphorylase kinase activity namespace: molecular_function def: "Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a." [EC:2.7.11.19] subset: gosubset_prok synonym: "ATP:phosphorylase-b phosphotransferase activity" EXACT [EC:2.7.11.19] synonym: "dephosphophosphorylase kinase activity" EXACT [EC:2.7.11.19] synonym: "glycogen phosphorylase kinase activity" EXACT [EC:2.7.11.19] synonym: "PHK" RELATED [EC:2.7.11.19] synonym: "phosphorylase b kinase activity" EXACT [EC:2.7.11.19] synonym: "phosphorylase B kinase activity" EXACT [EC:2.7.11.19] synonym: "phosphorylase kinase (phosphorylating) activity" EXACT [EC:2.7.11.19] synonym: "phosphorylase kinase, intrinsic catalyst activity" EXACT [] synonym: "STK17" RELATED [EC:2.7.11.19] xref: EC:2.7.11.19 xref: GO:0004689 xref: GO:0008606 xref: MetaCyc:PHOSPHORYLASE-KINASE-RXN xref: Reactome:13545 is_a: CCO:F0001053 ! calmodulin-dependent protein kinase activity [Term] id: CCO:F0001057 name: cyclic nucleotide-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of a cyclic nucleotide." [GOC:mah] xref: EC:2.7.11.- xref: GO:0004690 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001058 name: cAMP-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cAMP." [EC:2.7.11.11] synonym: "3',5' cAMP-dependent protein kinase activity" EXACT [] synonym: "3',5'-cAMP-dependent protein kinase activity" EXACT [] synonym: "adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [] synonym: "AMPK" RELATED [EC:2.7.11.11] synonym: "ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [EC:2.7.11.11] synonym: "cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [] synonym: "cyclic AMP-dependent protein kinase activity" EXACT [] synonym: "PKA" RELATED [EC:2.7.11.11] synonym: "PKA C" RELATED [EC:2.7.11.11] synonym: "protein kinase A activity" BROAD [EC:2.7.11.11] synonym: "STK22" RELATED [EC:2.7.11.11] xref: EC:2.7.11.11 xref: GO:0004691 xref: GO:0008602 xref: Reactome:13562 is_a: CCO:F0001057 ! cyclic nucleotide-dependent protein kinase activity [Term] id: CCO:F0001059 name: cGMP-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the presence of cGMP." [GOC:mah] synonym: "3':5'-cyclic GMP-dependent protein kinase activity" EXACT [EC:2.7.11.12] synonym: "ATP:protein phosphotransferase (cGMP-dependent) activity" EXACT [EC:2.7.11.12] synonym: "cGMP-dependent protein kinase ibeta activity" EXACT [EC:2.7.11.12] synonym: "guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity" EXACT [EC:2.7.11.12] synonym: "PKG" RELATED [EC:2.7.11.12] synonym: "PKG 1alpha" RELATED [EC:2.7.11.12] synonym: "PKG 1beta" RELATED [EC:2.7.11.12] synonym: "PKG II" RELATED [EC:2.7.11.12] synonym: "STK23" RELATED [EC:2.7.11.12] xref: EC:2.7.11.12 xref: GO:0004692 is_a: CCO:F0001057 ! cyclic nucleotide-dependent protein kinase activity [Term] id: CCO:F0001060 name: cyclin-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; dependent on the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK)." [GOC:rn, PMID:7877684, PMID:9841670] synonym: "ATP:cyclin phosphotransferase activity" EXACT [EC:2.7.11.22] synonym: "Bur1" RELATED [EC:2.7.11.22] synonym: "Bur1 Cdk" RELATED [EC:2.7.11.22] synonym: "Cak1" RELATED [EC:2.7.11.22] synonym: "Cak1p" RELATED [EC:2.7.11.22] synonym: "cdc2" RELATED [EC:2.7.11.22] synonym: "cdc2 kinase activity" NARROW [EC:2.7.11.22] synonym: "Cdc28p" RELATED [EC:2.7.11.22] synonym: "CDK" RELATED [EC:2.7.11.22] synonym: "CDK activity" EXACT [] synonym: "CDK, catalytic subunit activity" EXACT [] synonym: "cdk-activating kinase activity" EXACT [EC:2.7.11.22] synonym: "Cdk-activating protein kinase activity" EXACT [EC:2.7.11.22] synonym: "cdk1" RELATED [EC:2.7.11.22] synonym: "cdk2" RELATED [EC:2.7.11.22] synonym: "Cdk2" RELATED [EC:2.7.11.22] synonym: "cdk3" RELATED [EC:2.7.11.22] synonym: "cdk4" RELATED [EC:2.7.11.22] synonym: "cdk5" RELATED [EC:2.7.11.22] synonym: "cdk6" RELATED [EC:2.7.11.22] synonym: "cdk7" RELATED [EC:2.7.11.22] synonym: "cdk8" RELATED [EC:2.7.11.22] synonym: "cdk9" RELATED [EC:2.7.11.22] synonym: "cyclin A-activated cdc2" RELATED [EC:2.7.11.22] synonym: "cyclin A-activated cdk2" RELATED [EC:2.7.11.22] synonym: "cyclin D-cdk6 kinase activity" NARROW [EC:2.7.11.22] synonym: "cyclin D-dependent kinase activity" NARROW [EC:2.7.11.22] synonym: "cyclin E kinase activity" NARROW [EC:2.7.11.22] synonym: "cyclin-A associated kinase activity" NARROW [EC:2.7.11.22] synonym: "cyclin-dependent kinase 6 activity" NARROW [EC:2.7.11.22] synonym: "cyclin-dependent kinase activity" BROAD [EC:2.7.11.22] synonym: "cyclin-dependent kinase-2 activity" NARROW [EC:2.7.11.22] synonym: "cyclin-dependent kinase-4 activity" NARROW [EC:2.7.11.22] synonym: "cyclin-dependent protein kinase, intrinsic catalyst activity" EXACT [] synonym: "cyk" RELATED [EC:2.7.11.22] synonym: "D-type cyclin kinase activity" NARROW [EC:2.7.11.22] synonym: "nclk" RELATED [EC:2.7.11.22] synonym: "neuronal cdc2-like kinase activity" NARROW [EC:2.7.11.22] synonym: "PCTAIRE-1" RELATED [EC:2.7.11.22] synonym: "STK25" RELATED [EC:2.7.11.22] xref: EC:2.7.11.22 xref: GO:0004693 xref: GO:0016537 xref: Reactome:13565 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001061 name: eukaryotic translation initiation factor 2alpha kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (EIF2)." [GOC:mah, InterPro:IPR015516] xref: EC:2.7.11.- xref: GO:0004694 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001062 name: galactosyltransferase-associated kinase activity namespace: molecular_function xref: EC:2.7.11.- xref: GO:0004695 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001063 name: glycogen synthase kinase 3 activity namespace: molecular_function xref: EC:2.7.11.- xref: GO:0004696 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001064 name: protein kinase C activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol." [EC:2.7.11.13] synonym: "ATP:protein phosphotransferase (diacylglycerol-dependent) activity" EXACT [EC:2.7.11.13] synonym: "cPKC" RELATED [EC:2.7.11.13] synonym: "cPKCalpha" RELATED [EC:2.7.11.13] synonym: "cPKCbeta" RELATED [EC:2.7.11.13] synonym: "cPKCgamma" RELATED [EC:2.7.11.13] synonym: "diacylglycerol-activated phospholipid-dependent PKC activity" EXACT [] synonym: "diacylglycerol-activated phospholipid-dependent protein kinase C activity" EXACT [] synonym: "nPKC" RELATED [EC:2.7.11.13] synonym: "nPKCdelta" RELATED [EC:2.7.11.13] synonym: "nPKCepsilon" RELATED [EC:2.7.11.13] synonym: "nPKCeta" RELATED [EC:2.7.11.13] synonym: "nPKCtheta" RELATED [EC:2.7.11.13] synonym: "PKC" RELATED [EC:2.7.11.13] synonym: "PKC activity" EXACT [] synonym: "Pkc1p" RELATED [EC:2.7.11.13] synonym: "PKCalpha" RELATED [EC:2.7.11.13] synonym: "PKCbeta" RELATED [EC:2.7.11.13] synonym: "PKCdelta" RELATED [EC:2.7.11.13] synonym: "PKCepsilon" RELATED [EC:2.7.11.13] synonym: "PKCgamma" RELATED [EC:2.7.11.13] synonym: "PKCzeta" RELATED [EC:2.7.11.13] synonym: "protein kinase Cepsilon activity" NARROW [EC:2.7.11.13] synonym: "STK24" RELATED [EC:2.7.11.13] xref: EC:2.7.11.13 xref: GO:0004697 xref: GO:0004701 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001065 name: calcium-dependent protein kinase C activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol and calcium." [EC:2.7.11.13, GOC:mah] synonym: "calcium-dependent PKC activity" EXACT [] xref: EC:2.7.11.- xref: GO:0004698 xref: Reactome:13572 is_a: CCO:F0001064 ! protein kinase C activity [Term] id: CCO:F0001066 name: calcium-independent protein kinase C activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein, with a requirement for diacylglycerol but not calcium." [EC:2.7.11.13, GOC:mah] synonym: "calcium-independent PKC activity" EXACT [] xref: GO:0004699 is_a: CCO:F0001064 ! protein kinase C activity [Term] id: CCO:F0001067 name: atypical protein kinase C activity namespace: molecular_function synonym: "atypical PKC activity" EXACT [] xref: EC:2.7.11.- xref: GO:0004700 is_a: CCO:F0001064 ! protein kinase C activity [Term] id: CCO:F0001068 name: receptor signaling protein serine/threonine kinase activity namespace: molecular_function synonym: "receptor signalling protein serine/threonine kinase activity" EXACT [] xref: EC:2.7.11.- xref: GO:0004702 is_a: CCO:F0001045 ! protein serine/threonine kinase activity is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001069 name: G-protein coupled receptor kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of a G-protein coupled receptor, thereby modulating its activity." [GOC:dph] synonym: "ATP:G-protein-coupled receptor phosphotransferase activity" EXACT [EC:2.7.11.16] synonym: "G protein coupled receptor phosphorylating protein kinase activity" EXACT [] synonym: "G protein-coupled receptor kinase activity" EXACT [EC:2.7.11.16] synonym: "G-protein-coupled receptor kinase activity" EXACT [EC:2.7.11.16] synonym: "G-protein-coupled receptor phosphorylating protein kinase activity" EXACT [] synonym: "GPCR kinase activity" EXACT [EC:2.7.11.16] synonym: "GPCR phosphorylating protein kinase activity" EXACT [] synonym: "GPCRK" RELATED [EC:2.7.11.16] synonym: "GRK4" RELATED [EC:2.7.11.16] synonym: "GRK5" RELATED [EC:2.7.11.16] synonym: "GRK6" RELATED [EC:2.7.11.16] synonym: "STK16" RELATED [EC:2.7.11.16] xref: EC:2.7.11.16 xref: GO:0004678 xref: GO:0004703 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001070 name: NF-kappaB-inducing kinase activity namespace: molecular_function synonym: "NIK" EXACT [] xref: EC:2.7.11.- xref: GO:0004704 is_a: CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity [Term] id: CCO:F0001071 name: JUN kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "c-Jun N-terminal kinase activity" NARROW [] synonym: "JNK" EXACT [] synonym: "JNK3alpha1" RELATED [] synonym: "SAPK1" NARROW [] xref: EC:2.7.11.- xref: GO:0004705 is_a: CCO:F0003465 ! SAP kinase activity [Term] id: CCO:F0001072 name: JUN kinase kinase kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation and activation of JUN kinase kinases (JNKKs)." [GOC:bf] synonym: "JNK kinase kinase activity" RELATED [] synonym: "JNKKK" EXACT [] xref: EC:2.7.11.- xref: GO:0004706 is_a: CCO:F0001075 ! MAP kinase kinase kinase activity [Term] id: CCO:F0001073 name: MAP kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli." [GOC:ma, ISBN:0198547684] synonym: "ATP:protein phosphotransferase (MAPKK-activated) activity" EXACT [EC:2.7.11.24] synonym: "Dp38" RELATED [EC:2.7.11.24] synonym: "ERK" RELATED [EC:2.7.11.24] synonym: "extracellular signal-regulated kinase activity" NARROW [EC:2.7.11.24] synonym: "LeMPK3" RELATED [EC:2.7.11.24] synonym: "MAP-2 kinase activity" NARROW [EC:2.7.11.24] synonym: "MAPK" RELATED [EC:2.7.11.24] synonym: "MBP kinase I activity" NARROW [EC:2.7.11.24] synonym: "MBP kinase II activity" NARROW [EC:2.7.11.24] synonym: "mitogen activated kinase activity" EXACT [] synonym: "mitogen-activated protein kinase activity" EXACT [EC:2.7.11.24] synonym: "myelin basic protein kinase activity" NARROW [EC:2.7.11.24] synonym: "p38-2" RELATED [EC:2.7.11.24] synonym: "p38delta" RELATED [EC:2.7.11.24] synonym: "p42 mitogen-activated protein kinase activity" NARROW [EC:2.7.11.24] synonym: "p42mapk" RELATED [EC:2.7.11.24] synonym: "p44mpk" RELATED [EC:2.7.11.24] synonym: "PMK-1" RELATED [EC:2.7.11.24] synonym: "PMK-2" RELATED [EC:2.7.11.24] synonym: "PMK-3" RELATED [EC:2.7.11.24] synonym: "pp42" RELATED [EC:2.7.11.24] synonym: "pp44mapk" RELATED [EC:2.7.11.24] synonym: "STK26" RELATED [EC:2.7.11.24] xref: EC:2.7.11.24 xref: GO:0004707 xref: Reactome:4049 is_a: CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity [Term] id: CCO:F0001074 name: MAP kinase kinase activity namespace: molecular_function def: "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in MAP kinases. It is a dual-specificity mitogen-activated protein kinase kinase and requires activation by the serine/threonine kinase, MAP kinase kinase kinase." [ISBN:0198547684] synonym: "ATP:protein phosphotransferase (MAPKKK-activated) activity" EXACT [EC:2.7.12.2] synonym: "ERK activator kinase activity" EXACT [] synonym: "MAP kinase kinase 4 activity" NARROW [EC:2.7.12.2] synonym: "MAP kinase kinase 7 activity" NARROW [EC:2.7.12.2] synonym: "MAP kinase or ERK kinase activity" RELATED [EC:2.7.12.2] synonym: "MAP2K" RELATED [EC:2.7.12.2] synonym: "MAPKK" RELATED [EC:2.7.12.2] synonym: "MAPKK activity" EXACT [] synonym: "MAPKK1" RELATED [EC:2.7.12.2] synonym: "MEK activity" BROAD [] synonym: "MEK1" RELATED [EC:2.7.12.2] synonym: "MEK2" RELATED [EC:2.7.12.2] synonym: "mitogen-activated protein kinase kinase activity" EXACT [EC:2.7.12.2] synonym: "MKK" RELATED [EC:2.7.12.2] synonym: "MKK2" RELATED [EC:2.7.12.2] synonym: "MKK4" RELATED [EC:2.7.12.2] synonym: "MKK6" RELATED [EC:2.7.12.2] synonym: "MKK7" RELATED [EC:2.7.12.2] synonym: "STK27" RELATED [EC:2.7.12.2] xref: EC:2.7.11.- xref: GO:0004708 is_a: CCO:F0001078 ! protein serine/threonine/tyrosine kinase activity [Term] id: CCO:F0001075 name: MAP kinase kinase kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation and activation of MAP kinase kinases; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases." [PMID:9561267] synonym: "ATP:protein phosphotransferase (MAPKKKK-activated) activity" EXACT [EC:2.7.11.25] synonym: "cMos" RELATED [EC:2.7.11.25] synonym: "cRaf" RELATED [EC:2.7.11.25] synonym: "MAP3K" RELATED [EC:2.7.11.25] synonym: "MAPKKK activity" EXACT [EC:2.7.11.25] synonym: "MEK kinase activity" EXACT [EC:2.7.11.25] synonym: "MEKK" RELATED [EC:2.7.11.25] synonym: "MEKK1" RELATED [EC:2.7.11.25] synonym: "MEKK2" RELATED [EC:2.7.11.25] synonym: "MEKK3" RELATED [EC:2.7.11.25] synonym: "Mil/Raf" RELATED [EC:2.7.11.25] synonym: "mitogen-activated protein kinase kinase kinase activity" EXACT [EC:2.7.11.25] synonym: "MLK-like mitogen-activated protein triple kinase activity" NARROW [EC:2.7.11.25] synonym: "MLTK" RELATED [EC:2.7.11.25] synonym: "MLTKa" RELATED [EC:2.7.11.25] synonym: "MLTKb" RELATED [EC:2.7.11.25] synonym: "REKS" RELATED [EC:2.7.11.25] synonym: "STK28" RELATED [EC:2.7.11.25] xref: EC:2.7.11.25 xref: GO:0004709 is_a: CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity [Term] id: CCO:F0001076 name: MAP/ERK kinase kinase activity namespace: molecular_function synonym: "MEKK activity" EXACT [] xref: EC:2.7.11.- xref: GO:0004710 is_a: CCO:F0001075 ! MAP kinase kinase kinase activity [Term] id: CCO:F0001077 name: ribosomal protein S6 kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of ribosomal protein S6." [GOC:mah, PMID:9822608] xref: EC:2.7.11.- xref: GO:0004711 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001078 name: protein serine/threonine/tyrosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein serine/threonine/tyrosine = ADP + protein serine/threonine/tyrosine phosphate." [GOC:mah] subset: gosubset_prok synonym: "ADK1" RELATED [EC:2.7.12.1] synonym: "Arabidopsis dual specificity kinase 1 activity" NARROW [EC:2.7.12.1] synonym: "ATP:protein phosphotransferase (Ser/Thr- and Tyr-phosphorylating) activity" EXACT [EC:2.7.12.1] synonym: "CLK1" RELATED [EC:2.7.12.1] synonym: "dDYRK2" RELATED [EC:2.7.12.1] synonym: "dual-specificity kinase activity" BROAD [EC:2.7.12.1] synonym: "dual-specificity protein kinase" BROAD [] synonym: "Mps1p" RELATED [EC:2.7.12.1] synonym: "protein threonine/tyrosine kinase activity" NARROW [] xref: EC:2.7.112.1 xref: GO:0004712 is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0001080 name: transmembrane receptor protein tyrosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate, to initiate a change in cell activity." [EC:2.7.10.1, GOC:mah] subset: gosubset_prok synonym: "anaplastic lymphoma kinase activity" NARROW [EC:2.7.10.1] synonym: "ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity" EXACT [EC:2.7.10.1] synonym: "ATP:protein-tyrosine O-phosphotransferase activity" BROAD [EC:2.7.10.1] synonym: "Drosophila Eph kinase activity" NARROW [EC:2.7.10.1] synonym: "ephrin-B3 receptor tyrosine kinase activity" NARROW [EC:2.7.10.1] synonym: "insulin receptor protein-tyrosine kinase activity" NARROW [EC:2.7.10.1] synonym: "neurite outgrowth regulating kinase activity" NARROW [EC:2.7.10.1] synonym: "neurotrophin TRK receptor activity" RELATED [] synonym: "neurotrophin TRKA receptor activity" RELATED [] synonym: "neurotrophin TRKB receptor activity" RELATED [] synonym: "neurotrophin TRKC receptor activity" RELATED [] synonym: "novel oncogene with kinase-domain activity" NARROW [EC:2.7.10.1] synonym: "receptor protein tyrosine kinase activity" EXACT [EC:2.7.10.1] synonym: "receptor protein-tyrosine kinase activity" EXACT [EC:2.7.10.1] synonym: "sevenless receptor activity" RELATED [] xref: EC:2.7.10.1 xref: GO:0004714 xref: Reactome:11064 is_a: CCO:F0004122 ! transmembrane receptor protein kinase activity is_a: CCO:F0008374 ! protein tyrosine kinase activity [Term] id: CCO:F0001081 name: non-membrane spanning protein tyrosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate." [EC:2.7.10.2] synonym: "ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [EC:2.7.10.2] synonym: "ATP:protein-tyrosine O-phosphotransferase activity" BROAD [EC:2.7.10.2] synonym: "Bruton's tyrosine kinase activity" NARROW [EC:2.7.10.2] synonym: "cytoplasmic protein tyrosine kinase activity" NARROW [EC:2.7.10.2] synonym: "focal adhesion kinase activity" NARROW [EC:2.7.10.2] synonym: "janus kinase 1 activity" NARROW [EC:2.7.10.2] synonym: "janus kinase 2 activity" NARROW [EC:2.7.10.2] synonym: "janus kinase 3 activity" NARROW [EC:2.7.10.2] synonym: "non-specific protein-tyrosine kinase activity" EXACT [EC:2.7.10.2] synonym: "p60c-src protein tyrosine kinase activity" NARROW [EC:2.7.10.2] xref: EC:2.7.10.2 xref: GO:0004715 is_a: CCO:F0008374 ! protein tyrosine kinase activity [Term] id: CCO:F0001082 name: receptor signaling protein tyrosine kinase activity namespace: molecular_function synonym: "receptor signalling protein tyrosine kinase activity" EXACT [] xref: EC:2.7.10.- xref: GO:0004716 is_a: CCO:F0001374 ! receptor signaling protein activity is_a: CCO:F0008374 ! protein tyrosine kinase activity [Term] id: CCO:F0001083 name: Janus kinase activity namespace: molecular_function synonym: "JAK" EXACT [] xref: EC:2.7.11.- xref: GO:0004718 is_a: CCO:F0001082 ! receptor signaling protein tyrosine kinase activity [Term] id: CCO:F0001084 name: protein-L-isoaspartate (D-aspartate) O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester." [EC:2.1.1.77] subset: gosubset_prok synonym: "D-aspartyl/L-isoaspartyl methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "L-aspartyl/L-isoaspartyl protein methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "L-isoaspartyl protein carboxyl methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein (D-aspartate) methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein beta-aspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein D-aspartate methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein L-isoaspartate methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein L-isoaspartyl methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein O-methyltransferase (L-isoaspartate)" EXACT [EC:2.1.1.77] synonym: "protein-beta-aspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein-L-isoaspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "protein-L-isoaspartate(D-aspartate) O-methyltransferase activity" EXACT [EC:2.1.1.77] synonym: "S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase activity" EXACT [EC:2.1.1.77] xref: EC:2.1.1.77 xref: GO:0004719 xref: MetaCyc:2.1.1.77-RXN is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0001813 ! protein methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001085 name: protein-lysine 6-oxidase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + H2O2." [EC:1.4.3.13] synonym: "lysyl oxidase activity" EXACT [EC:1.4.3.13] synonym: "protein-L-lysine:oxygen 6-oxidoreductase (deaminating)" EXACT [EC:1.4.3.13] xref: EC:1.4.3.13 xref: GO:0004720 xref: GO:0018056 xref: MetaCyc:PROTEIN-LYSINE-6-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0001086 name: phosphoprotein phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity." [EC:3.1.3.16, ISBN:0198547684] subset: goslim_candida subset: goslim_generic subset: goslim_yeast subset: gosubset_prok synonym: "phosphoprotein phosphohydrolase activity" EXACT [EC:3.1.3.16] synonym: "protein phosphatase activity" EXACT [] synonym: "protein phosphatase-1 activity" NARROW [EC:3.1.3.16] synonym: "protein phosphatase-2A activity" NARROW [EC:3.1.3.16] synonym: "protein phosphatase-2B activity" NARROW [EC:3.1.3.16] synonym: "protein phosphatase-2C activity" NARROW [EC:3.1.3.16] xref: EC:3.1.3.16 xref: GO:0004721 xref: MetaCyc:3.1.3.16-RXN xref: Reactome:1887 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0001087 name: protein serine/threonine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate." [GOC:bf] subset: gosubset_prok synonym: "3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase" NARROW [EC:3.1.3.16] synonym: "Aspergillus awamori acid protein phosphatase" NARROW [EC:3.1.3.16] synonym: "BCKDH phosphatase" NARROW [EC:3.1.3.16] synonym: "branched-chain alpha-keto acid dehydrogenase phosphatase" NARROW [EC:3.1.3.16] synonym: "calcineurin" NARROW [] synonym: "casein phosphatase" NARROW [EC:3.1.3.16] synonym: "HMG-CoA reductase phosphatase" NARROW [EC:3.1.3.16] synonym: "phosphatase 2A" NARROW [EC:3.1.3.16] synonym: "phosphatase 2B" NARROW [EC:3.1.3.16] synonym: "phosphatase C-II" NARROW [EC:3.1.3.16] synonym: "phosphatase H-II" NARROW [EC:3.1.3.16] synonym: "phosphatase I" NARROW [EC:3.1.3.16] synonym: "phosphatase IB" NARROW [EC:3.1.3.16] synonym: "phosphatase II" NARROW [EC:3.1.3.16] synonym: "phosphatase III" NARROW [EC:3.1.3.16] synonym: "phosphatase IV" NARROW [EC:3.1.3.16] synonym: "phosphatase SP" NARROW [EC:3.1.3.16] synonym: "phosphopyruvate dehydrogenase phosphatase" NARROW [EC:3.1.3.16] synonym: "phosphospectrin phosphatase" NARROW [EC:3.1.3.16] synonym: "polycation modulated (PCM-) phosphatase" NARROW [EC:3.1.3.16] synonym: "protein D phosphatase" NARROW [EC:3.1.3.16] synonym: "protein phosphatase type 1 activity" NARROW [] synonym: "protein phosphatase type 1, intrinsic catalyst activity" NARROW [] synonym: "protein phosphatase type 2A activity" NARROW [] synonym: "protein phosphatase type 2A, intrinsic catalyst activity" NARROW [] synonym: "protein phosphatase type 2B activity" NARROW [] synonym: "protein phosphatase type 2B, intrinsic catalyst activity" NARROW [] synonym: "protein phosphatase type 2C activity" NARROW [] synonym: "protein phosphatase type 4 activity" NARROW [] synonym: "protein phosphatase type 4, intrinsic catalyst activity" NARROW [] synonym: "protein phosphatase X" NARROW [] synonym: "serine/threonine specific protein phosphatase activity" EXACT [] xref: GO:0000158 xref: GO:0000163 xref: GO:0004722 xref: GO:0008598 xref: GO:0008600 xref: GO:0015071 xref: GO:0030357 xref: GO:0030358 xref: GO:0030360 xref: GO:0030361 xref: Reactome:21718 is_a: CCO:F0001086 ! phosphoprotein phosphatase activity [Term] id: CCO:F0001088 name: calcium-dependent protein serine/threonine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium ions." [EC:3.1.3.16, GOC:mah] synonym: "calcineurin" NARROW [] synonym: "calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity" EXACT [] xref: GO:0004723 xref: GO:0008596 is_a: CCO:F0001087 ! protein serine/threonine phosphatase activity [Term] id: CCO:F0001089 name: magnesium-dependent protein serine/threonine phosphatase activity namespace: molecular_function def: "Catalysis of the removal of a serine- or threonine-bound phosphate group from a protein; action dependent on magnesium." [EC:3.1.3.16] xref: GO:0004724 is_a: CCO:F0001087 ! protein serine/threonine phosphatase activity [Term] id: CCO:F0001090 name: protein tyrosine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [EC:3.1.3.48] subset: gosubset_prok synonym: "[phosphotyrosine]protein phosphatase activity" EXACT [EC:3.1.3.48] synonym: "phosphoprotein phosphatase (phosphotyrosine) activity" EXACT [EC:3.1.3.48] synonym: "phosphotyrosine histone phosphatase activity" EXACT [EC:3.1.3.48] synonym: "phosphotyrosine phosphatase activity" EXACT [EC:3.1.3.48] synonym: "phosphotyrosine protein phosphatase activity" EXACT [EC:3.1.3.48] synonym: "phosphotyrosylprotein phosphatase activity" EXACT [EC:3.1.3.48] synonym: "PPT-phosphatase activity" EXACT [EC:3.1.3.48] synonym: "protein phosphotyrosine phosphatase activity" EXACT [EC:3.1.3.48] synonym: "protein-tyrosine-phosphatase activity" EXACT [EC:3.1.3.48] synonym: "protein-tyrosine-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.48] synonym: "PTP-phosphatase activity" EXACT [EC:3.1.3.48] synonym: "PTPase activity" EXACT [EC:3.1.3.48] synonym: "tyrosine O-phosphate phosphatase activity" EXACT [EC:3.1.3.48] synonym: "tyrosylprotein phosphatase activity" EXACT [EC:3.1.3.48] xref: EC:3.1.3.48 xref: GO:0004725 xref: MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN xref: Reactome:11061 is_a: CCO:F0001086 ! phosphoprotein phosphatase activity [Term] id: CCO:F0001091 name: non-membrane spanning protein tyrosine phosphatase activity namespace: molecular_function subset: gosubset_prok xref: GO:0004726 is_a: CCO:F0001090 ! protein tyrosine phosphatase activity [Term] id: CCO:F0001092 name: prenylated protein tyrosine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate." [EC:3.1.3.48] xref: GO:0004727 is_a: CCO:F0001090 ! protein tyrosine phosphatase activity [Term] id: CCO:F0001093 name: receptor signaling protein tyrosine phosphatase activity namespace: molecular_function synonym: "receptor signalling protein tyrosine phosphatase activity" EXACT [] xref: GO:0004728 is_a: CCO:F0001090 ! protein tyrosine phosphatase activity is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001094 name: protoporphyrinogen oxidase activity namespace: molecular_function def: "Catalysis of the reaction: protoporphyrinogen-IX + O2 = protoporphyrin-IX + H2O2." [EC:1.3.3.4] subset: gosubset_prok synonym: "protoporphyrinogen IX oxidase activity" EXACT [EC:1.3.3.4] synonym: "protoporphyrinogen-IX oxidase activity" EXACT [EC:1.3.3.4] synonym: "protoporphyrinogen-IX:oxygen oxidoreductase activity" EXACT [EC:1.3.3.4] synonym: "protoporphyrinogenase activity" EXACT [EC:1.3.3.4] xref: EC:1.3.3.4 xref: GO:0004729 xref: MetaCyc:PROTOPORGENOXI-RXN xref: Reactome:14184 is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0001095 name: pseudouridylate synthase activity namespace: molecular_function def: "Catalysis of the reaction: uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H2O." [EC:4.2.1.70] comment: Note that this term should not be confused with 'pseudouridine synthase activity ; GO:0009982', which refers to the intramolecular isomerization of uridine to pseudouridine. subset: gosubset_prok synonym: "5-ribosyluracil 5-phosphate synthetase activity" EXACT [EC:4.2.1.70] synonym: "pseudouridine monophosphate synthase activity" EXACT [] synonym: "pseudouridine monophosphate synthetase activity" EXACT [EC:4.2.1.70] synonym: "pseudouridylate synthetase activity" EXACT [EC:4.2.1.70] synonym: "pseudouridylic acid synthetase activity" EXACT [EC:4.2.1.70] synonym: "psiUMP synthetase activity" EXACT [EC:4.2.1.70] synonym: "uracil hydro-lyase (adding D-ribose 5-phosphate)" EXACT [EC:4.2.1.70] synonym: "uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming)" EXACT [EC:4.2.1.70] synonym: "uracil hydrolyase activity" RELATED [EC:4.2.1.70] xref: EC:4.2.1.70 xref: GO:0004730 xref: MetaCyc:PSEUDOURIDYLATE-SYNTHASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001096 name: purine-nucleoside phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate." [EC:2.4.2.1] subset: gosubset_prok synonym: "inosine phosphorylase activity" NARROW [EC:2.4.2.1] synonym: "inosine-guanosine phosphorylase activity" EXACT [EC:2.4.2.1] synonym: "PNPase activity" EXACT [EC:2.4.2.1] synonym: "PUNPI" RELATED [EC:2.4.2.1] synonym: "PUNPII" RELATED [EC:2.4.2.1] synonym: "purine deoxynucleoside phosphorylase activity" EXACT [EC:2.4.2.1] synonym: "purine deoxyribonucleoside phosphorylase activity" EXACT [EC:2.4.2.1] synonym: "purine nucleoside phosphorylase activity" EXACT [EC:2.4.2.1] synonym: "purine ribonucleoside phosphorylase activity" EXACT [EC:2.4.2.1] synonym: "purine-nucleoside:phosphate ribosyltransferase activity" EXACT [EC:2.4.2.1] xref: EC:2.4.2.1 xref: GO:0004731 xref: MetaCyc:PNP-RXN xref: Reactome:14201 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0001097 name: pyridoxal oxidase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + H2O2." [EC:1.2.3.8] synonym: "pyridoxal:oxygen 4-oxidoreductase activity" EXACT [EC:1.2.3.8] xref: EC:1.2.3.8 xref: GO:0004732 xref: MetaCyc:PYRIDOXAL-OXIDASE-RXN is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0001098 name: pyridoxamine-phosphate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + H2O2." [EC:1.4.3.5] subset: gosubset_prok synonym: "PdxH" RELATED [EC:1.4.3.5] synonym: "PMP oxidase activity" EXACT [EC:1.4.3.5] synonym: "pyridoxal 5'-phosphate synthase activity" EXACT [EC:1.4.3.5] synonym: "pyridoxamine 5'-phosphate oxidase activity" EXACT [EC:1.4.3.5] synonym: "pyridoxamine phosphate oxidase activity" EXACT [EC:1.4.3.5] synonym: "pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.5] synonym: "pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating)" EXACT [EC:1.4.3.5] synonym: "pyridoxine (pyridoxamine) 5'-phosphate oxidase activity" EXACT [EC:1.4.3.5] synonym: "pyridoxine (pyridoxamine)phosphate oxidase activity" EXACT [EC:1.4.3.5] synonym: "pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.5] xref: EC:1.4.3.5 xref: GO:0004733 xref: MetaCyc:PMPOXI-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0001099 name: pyrimidodiazepine synthase activity namespace: molecular_function def: "Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione." [EC:1.5.4.1] synonym: "PDA synthase activity" EXACT [EC:1.5.4.1] synonym: "pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)" EXACT [EC:1.5.4.1] xref: EC:1.5.4.1 xref: GO:0004734 xref: MetaCyc:1.5.4.1-RXN is_a: CCO:F0003247 ! oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor [Term] id: CCO:F0001100 name: pyrroline-5-carboxylate reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+." [EC:1.5.1.2] subset: gosubset_prok synonym: "1-pyrroline-5-carboxylate reductase activity" EXACT [EC:1.5.1.2] synonym: "L-proline oxidase activity" EXACT [EC:1.5.1.2] synonym: "L-proline-NAD(P)+ 5-oxidoreductase activity" EXACT [EC:1.5.1.2] synonym: "L-proline:NAD(P)+ 5-oxidoreductase activity" EXACT [EC:1.5.1.2] synonym: "NADPH-L-delta1-pyrroline carboxylic acid reductase activity" EXACT [EC:1.5.1.2] synonym: "P5CR activity" EXACT [EC:1.5.1.2] xref: EC:1.5.1.2 xref: GO:0004735 xref: MetaCyc:PYRROLINECARBREDUCT-RXN xref: Reactome:14208 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001101 name: pyruvate carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pyruvate + HCO3- = ADP + phosphate + oxaloacetate." [EC:6.4.1.1] subset: gosubset_prok synonym: "pyruvate:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.1] synonym: "pyruvic carboxylase activity" EXACT [EC:6.4.1.1] xref: EC:6.4.1.1 xref: GO:0004736 xref: MetaCyc:PYRUVATE-CARBOXYLASE-RXN xref: Reactome:14209 is_a: CCO:F0003443 ! ligase activity, forming carbon-carbon bonds [Term] id: CCO:F0001102 name: pyruvate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2." [EC:4.1.1.1] subset: gosubset_prok synonym: "2-oxo-acid carboxy-lyase (aldehyde-forming)" EXACT [EC:4.1.1.1] synonym: "2-oxo-acid carboxy-lyase activity" EXACT [EC:4.1.1.1] synonym: "alpha-carboxylase activity" EXACT [EC:4.1.1.1] synonym: "alpha-ketoacid carboxylase activity" EXACT [EC:4.1.1.1] synonym: "pyruvic decarboxylase activity" EXACT [EC:4.1.1.1] xref: EC:4.1.1.1 xref: GO:0004737 xref: MetaCyc:PYRUVATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0001103 name: pyruvate dehydrogenase activity namespace: molecular_function def: "Catalysis of the oxidative decarboxylation of pyruvate." [ISBN:0716020094] subset: gosubset_prok synonym: "pyruvic acid dehydrogenase activity" EXACT [EC:1.2.4.1] synonym: "pyruvic dehydrogenase activity" EXACT [EC:1.2.4.1] xref: GO:0004738 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0001104 name: pyruvate dehydrogenase (acetyl-transferring) activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2." [EC:1.2.4.1] subset: gosubset_prok synonym: "MtPDC (mitochondrial pyruvate dehydogenase complex) activity" NARROW [EC:1.2.4.1] synonym: "PDH" RELATED [EC:1.2.4.1] synonym: "pyruvate dehydrogenase (lipoamide) activity" EXACT [] synonym: "pyruvate dehydrogenase complex activity" RELATED [EC:1.2.4.1] synonym: "pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)" EXACT [EC:1.2.4.1] synonym: "pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity" EXACT [EC:1.2.4.1] xref: EC:1.2.4.1 xref: GO:0004739 xref: MetaCyc:PYRUVATEDECARB-RXN xref: Reactome:14213 is_a: CCO:F0001103 ! pyruvate dehydrogenase activity is_a: CCO:F0003226 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [Term] id: CCO:F0001105 name: pyruvate dehydrogenase (acetyl-transferring) kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate." [EC:2.7.11.2] synonym: "[pyruvate dehydrogenase (lipoamide)] kinase activity" EXACT [] synonym: "ATP:pyruvate dehydrogenase (acetyl-transferring) phosphotransferase activity" EXACT [EC:2.7.11.2] synonym: "PDH kinase activity" EXACT [EC:2.7.11.2] synonym: "PDHK" RELATED [EC:2.7.11.2] synonym: "PDK" RELATED [EC:2.7.11.2] synonym: "PDK1" RELATED [EC:2.7.11.2] synonym: "PDK2" RELATED [EC:2.7.11.2] synonym: "PDK3" RELATED [EC:2.7.11.2] synonym: "PDK4" RELATED [EC:2.7.11.2] synonym: "pyruvate dehydrogenase (lipoamide) kinase activity" EXACT [] synonym: "pyruvate dehydrogenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.2] synonym: "pyruvate dehydrogenase kinase activator protein activity" NARROW [EC:2.7.11.2] synonym: "pyruvate dehydrogenase kinase activity" EXACT [EC:2.7.11.2] synonym: "STK1" RELATED [EC:2.7.11.2] xref: EC:2.7.11.2 xref: GO:0004740 xref: MetaCyc:2.7.11.2-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0001107 name: dihydrolipoyllysine-residue acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide." [EC:2.3.1.12] subset: gosubset_prok synonym: "acetyl-CoA: enzyme-6-N-(dihydrolipoyl)lysine S-acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "acetyl-CoA: enzyme-N6-(dihydrolipoyl)lysine S-acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "acetyl-CoA:dihydrolipoamide S-acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "dihydrolipoamide S-acetyltransferase activity" EXACT [] synonym: "dihydrolipoate acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "dihydrolipoic transacetylase activity" EXACT [EC:2.3.1.12] synonym: "dihydrolipoyl acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "lipoate acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "lipoate transacetylase activity" EXACT [EC:2.3.1.12] synonym: "lipoic acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "lipoic acid acetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "lipoic transacetylase activity" EXACT [EC:2.3.1.12] synonym: "lipoylacetyltransferase activity" EXACT [EC:2.3.1.12] synonym: "thioltransacetylase A activity" NARROW [EC:2.3.1.12] synonym: "transacetylase X activity" NARROW [EC:2.3.1.12] xref: EC:2.3.1.12 xref: GO:0004742 xref: MetaCyc:DIHYDLIPACETRANS-RXN xref: Reactome:14238 is_a: CCO:F0003141 ! S-acetyltransferase activity is_a: CCO:F0004452 ! dihydrolipoamide S-acyltransferase activity [Term] id: CCO:F0001108 name: pyruvate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pyruvate = ADP + phosphoenolpyruvate." [EC:2.7.1.40] subset: gosubset_prok synonym: "ATP:pyruvate 2-O-phosphotransferase activity" EXACT [EC:2.7.1.40] synonym: "phosphoenol transphosphorylase activity" EXACT [EC:2.7.1.40] synonym: "phosphoenolpyruvate kinase activity" EXACT [EC:2.7.1.40] xref: EC:2.7.1.40 xref: GO:0004743 xref: MetaCyc:PEPDEPHOS-RXN xref: Reactome:14240 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0001109 name: retinal isomerase activity namespace: molecular_function def: "Catalysis of the reaction: all-trans-retinal = 11-cis-retinal." [EC:5.2.1.3] synonym: "all-trans-retinal 11-cis-trans-isomerase activity" EXACT [EC:5.2.1.3] synonym: "retinene isomerase activity" RELATED [EC:5.2.1.3] synonym: "retinoid isomerase activity" BROAD [EC:5.2.1.3] xref: EC:5.2.1.3 xref: GO:0004744 xref: MetaCyc:RETINAL-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0001110 name: retinol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+." [EC:1.1.1.105] subset: gosubset_prok synonym: "all-trans retinol dehydrogenase activity" EXACT [EC:1.1.1.105] synonym: "MDR" RELATED [EC:1.1.1.105] synonym: "microsomal retinol dehydrogenase activity" EXACT [EC:1.1.1.105] synonym: "retinene reductase activity" EXACT [EC:1.1.1.105] synonym: "retinol (vitamin A1) dehydrogenase activity" EXACT [EC:1.1.1.105] synonym: "retinol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.105] xref: EC:1.1.1.105 xref: GO:0004745 xref: MetaCyc:RETINOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001111 name: riboflavin synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine." [EC:2.5.1.9] subset: gosubset_prok synonym: "6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity" EXACT [EC:2.5.1.9] synonym: "heavy riboflavin synthase" NARROW [EC:2.5.1.9] synonym: "light riboflavin synthase" NARROW [EC:2.5.1.9] synonym: "lumazine synthase activity" BROAD [BRENDA:2.5.1.9] synonym: "riboflavin synthetase activity" EXACT [EC:2.5.1.9] synonym: "riboflavine synthase activity" EXACT [EC:2.5.1.9] synonym: "riboflavine synthetase activity" EXACT [EC:2.5.1.9] synonym: "vitamin B2 synthase activity" EXACT [] xref: EC:2.5.1.9 xref: GO:0004746 xref: MetaCyc:RIBOFLAVIN-SYN-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0001112 name: ribokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate." [EC:2.7.1.15] subset: gosubset_prok synonym: "ATP:D-ribose 5-phosphotransferase activity" EXACT [EC:2.7.1.15] synonym: "D-ribokinase activity" EXACT [EC:2.7.1.15] synonym: "deoxyribokinase activity" EXACT [EC:2.7.1.15] synonym: "ribokinase (phosphorylating)" EXACT [EC:2.7.1.15] xref: EC:2.7.1.15 xref: GO:0004747 xref: MetaCyc:RIBOKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0001113 name: ribonucleoside-diphosphate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin." [EC:1.17.4.1] subset: gosubset_prok synonym: "2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity" EXACT [EC:1.17.4.1] synonym: "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity" EXACT [EC:1.17.4.1] synonym: "nucleoside diphosphate reductase activity" EXACT [EC:1.17.4.1] synonym: "purine/pyrimidine nucleoside diphosphate reduction" RELATED [] synonym: "ribonucleoside 5'-diphosphate reductase activity" EXACT [EC:1.17.4.1] synonym: "ribonucleoside diphosphate reductase activity" EXACT [EC:1.17.4.1] synonym: "ribonucleotide diphosphate reductase activity" EXACT [EC:1.17.4.1] synonym: "ribonucleotide reductase activity" BROAD [EC:1.17.4.1] synonym: "RNR" EXACT [] xref: EC:1.17.4.1 xref: GO:0004748 xref: MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN is_a: CCO:F0003310 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor [Term] id: CCO:F0001114 name: ribose phosphate diphosphokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.7.6.1] subset: gosubset_prok synonym: "5-phosphoribose pyrophosphorylase activity" EXACT [EC:2.7.6.1] synonym: "5-phosphoribosyl-1-pyrophosphate synthetase activity" EXACT [EC:2.7.6.1] synonym: "5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity" EXACT [EC:2.7.6.1] synonym: "ATP:D-ribose-5-phosphate diphosphotransferase activity" EXACT [EC:2.7.6.1] synonym: "phosphoribosyl diphosphate synthetase activity" EXACT [EC:2.7.6.1] synonym: "phosphoribosyl pyrophosphate synthetase activity" EXACT [EC:2.7.6.1] synonym: "phosphoribosyl-diphosphate synthetase activity" EXACT [EC:2.7.6.1] synonym: "phosphoribosylpyrophosphate synthase activity" EXACT [EC:2.7.6.1] synonym: "phosphoribosylpyrophosphate synthetase activity" EXACT [EC:2.7.6.1] synonym: "PP-ribose P synthetase activity" EXACT [EC:2.7.6.1] synonym: "PPRibP synthetase activity" EXACT [EC:2.7.6.1] synonym: "PRPP synthetase activity" EXACT [EC:2.7.6.1] synonym: "pyrophosphoribosylphosphate synthetase activity" EXACT [EC:2.7.6.1] synonym: "ribophosphate pyrophosphokinase activity" EXACT [EC:2.7.6.1] synonym: "ribose-5-phosphate pyrophosphokinase activity" EXACT [EC:2.7.6.1] synonym: "ribose-phosphate diphosphokinase activity" EXACT [EC:2.7.6.1] synonym: "ribose-phosphate pyrophosphokinase activity" EXACT [] xref: EC:2.7.6.1 xref: GO:0004749 xref: MetaCyc:PRPPSYN-RXN xref: MetaCyc:PWY0-662 xref: Reactome:14245 is_a: CCO:F0003350 ! diphosphotransferase activity [Term] id: CCO:F0001115 name: ribulose-phosphate 3-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate." [EC:5.1.3.1] subset: gosubset_prok synonym: "D-ribulose 5-phosphate epimerase activity" EXACT [EC:5.1.3.1] synonym: "D-ribulose phosphate-3-epimerase activity" EXACT [EC:5.1.3.1] synonym: "D-ribulose-5-P 3-epimerase activity" EXACT [EC:5.1.3.1] synonym: "D-ribulose-5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] synonym: "D-ribulose-5-phosphate epimerase activity" EXACT [EC:5.1.3.1] synonym: "D-xylulose-5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] synonym: "erythrose-4-phosphate epimerase activity" EXACT [EC:5.1.3.1] synonym: "erythrose-4-phosphate isomerase activity" EXACT [EC:5.1.3.1] synonym: "pentose-5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] synonym: "phosphoketopentose 3-epimerase activity" EXACT [EC:5.1.3.1] synonym: "phosphoketopentose epimerase activity" EXACT [EC:5.1.3.1] synonym: "phosphoribulose epimerase activity" EXACT [EC:5.1.3.1] synonym: "ribulose 5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] synonym: "xylulose phosphate 3-epimerase activity" EXACT [EC:5.1.3.1] xref: EC:5.1.3.1 xref: GO:0004750 xref: MetaCyc:RIBULP3EPIM-RXN xref: Reactome:14262 is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0001116 name: ribose-5-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate." [EC:5.3.1.6] subset: gosubset_prok synonym: "5-phosphoribose isomerase activity" EXACT [EC:5.3.1.6] synonym: "D-ribose 5-phosphate isomerase activity" EXACT [EC:5.3.1.6] synonym: "D-ribose-5-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.6] synonym: "D-ribose-5-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.6] synonym: "phosphopentoseisomerase activity" EXACT [EC:5.3.1.6] synonym: "phosphopentosisomerase activity" EXACT [EC:5.3.1.6] synonym: "phosphoriboisomerase activity" EXACT [EC:5.3.1.6] synonym: "ribose 5-phosphate epimerase activity" EXACT [EC:5.3.1.6] synonym: "ribose phosphate isomerase activity" EXACT [EC:5.3.1.6] xref: EC:5.3.1.6 xref: GO:0004751 xref: MetaCyc:RIB5PISOM-RXN xref: Reactome:14263 is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0001117 name: saccharopine dehydrogenase activity namespace: molecular_function subset: gosubset_prok synonym: "lysine-2-oxoglutarate reductase activity" EXACT [EC:1.5.1.-] synonym: "lysine-ketoglutarate reductase activity" EXACT [EC:1.5.1.-] xref: EC:1.5.1.- xref: GO:0004753 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001118 name: saccharopine dehydrogenase (NAD+, L-lysine-forming) activity namespace: molecular_function def: "Catalysis of the reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+." [EC:1.5.1.7] subset: gosubset_prok synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.7] synonym: "dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming)" EXACT [EC:1.5.1.7] synonym: "epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)" EXACT [EC:1.5.1.7] synonym: "N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.7] synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.7] xref: EC:1.5.1.7 xref: GO:0004754 xref: MetaCyc:1.5.1.7-RXN xref: Reactome:70922 is_a: CCO:F0001117 ! saccharopine dehydrogenase activity [Term] id: CCO:F0001119 name: saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity namespace: molecular_function def: "Catalysis of the reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADPH + H+." [EC:1.5.1.10] subset: gosubset_prok synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.10] synonym: "aminoadipate semialdehyde-glutamate reductase activity" EXACT [EC:1.5.1.10] synonym: "aminoadipic semialdehyde-glutamate reductase activity" EXACT [EC:1.5.1.10] synonym: "aminoadipic semialdehyde-glutamic reductase activity" EXACT [EC:1.5.1.10] synonym: "epsilon-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)" EXACT [EC:1.5.1.10] synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.10] synonym: "saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase activity" EXACT [EC:1.5.1.10] synonym: "saccharopine reductase activity" EXACT [EC:1.5.1.10] xref: EC:1.5.1.10 xref: GO:0004755 xref: MetaCyc:1.5.1.10-RXN xref: Reactome:70935 is_a: CCO:F0001117 ! saccharopine dehydrogenase activity [Term] id: CCO:F0001120 name: selenide, water dikinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + selenide + H2O = AMP + selenophosphate + phosphate." [EC:2.7.9.3] subset: gosubset_prok synonym: "ATP:selenide, water phosphotransferase activity" EXACT [EC:2.7.9.3] synonym: "selenide,water dikinase activity" EXACT [EC:2.7.9.3] synonym: "selenium donor protein activity" EXACT [EC:2.7.9.3] synonym: "selenophosphate synthase activity" EXACT [] synonym: "selenophosphate synthetase activity" EXACT [EC:2.7.9.3] xref: EC:2.7.9.3 xref: GO:0004756 xref: MetaCyc:2.7.9.3-RXN xref: UM-BBD_enzymeID:e0509 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003353 ! phosphotransferase activity, paired acceptors [Term] id: CCO:F0001121 name: sepiapterin reductase activity namespace: molecular_function def: "Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+." [EC:1.1.1.153] subset: gosubset_prok synonym: "7,8-dihydrobiopterin:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.153] xref: EC:1.1.1.153 xref: GO:0004757 xref: MetaCyc:SEPIAPTERIN-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001122 name: serine C-palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2." [EC:2.3.1.50] synonym: "3-oxosphinganine synthetase activity" EXACT [EC:2.3.1.50] synonym: "acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [EC:2.3.1.50] synonym: "palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [EC:2.3.1.50] synonym: "serine palmitoyltransferase" BROAD [] synonym: "SPT" RELATED [EC:2.3.1.50] xref: EC:2.3.1.50 xref: GO:0004758 xref: MetaCyc:SERINE-C-PALMITOYLTRANSFERASE-RXN is_a: CCO:F0003164 ! C-palmitoyltransferase activity [Term] id: CCO:F0001123 name: serine-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine." [EC:2.6.1.51] subset: gosubset_prok synonym: "hydroxypyruvate:L-alanine transaminase activity" EXACT [EC:2.6.1.51] synonym: "L-serine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.51] synonym: "serine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.51] synonym: "serine-pyruvate aminotransferase activity" EXACT [] synonym: "serine-pyruvate aminotransferase, type 1" NARROW [] synonym: "serine-pyruvate aminotransferase, type 2A" NARROW [] synonym: "serine-pyruvate aminotransferase, type 2B" NARROW [] synonym: "SPT" RELATED [EC:2.6.1.51] xref: EC:2.6.1.51 xref: GO:0004760 xref: GO:0004761 xref: GO:0004762 xref: GO:0004763 xref: MetaCyc:SERINE--PYRUVATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0001124 name: shikimate 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: shikimate + NADP+ = 5-dehydroshikimate + NADPH + H+." [EC:1.1.1.25] subset: gosubset_prok synonym: "5-dehydroshikimate reductase activity" EXACT [EC:1.1.1.25] synonym: "5-dehydroshikimic reductase activity" EXACT [EC:1.1.1.25] synonym: "dehydroshikimic reductase activity" EXACT [EC:1.1.1.25] synonym: "DHS reductase activity" EXACT [EC:1.1.1.25] synonym: "shikimate oxidoreductase activity" EXACT [EC:1.1.1.25] synonym: "shikimate:NADP(+) 5-oxidoreductase activity" EXACT [EC:1.1.1.25] synonym: "shikimate:NADP(+) oxidoreductase activity" EXACT [EC:1.1.1.25] xref: EC:1.1.1.25 xref: GO:0004764 xref: MetaCyc:SHIKIMATE-5-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001125 name: shikimate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + shikimate = ADP + shikimate 3-phosphate." [EC:2.7.1.71] subset: gosubset_prok synonym: "ATP:shikimate 3-phosphotransferase activity" EXACT [EC:2.7.1.71] synonym: "shikimate kinase (phosphorylating)" EXACT [EC:2.7.1.71] synonym: "shikimate kinase II" RELATED [EC:2.7.1.71] xref: EC:2.7.1.71 xref: GO:0004765 xref: MetaCyc:SHIKIMATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0001126 name: spermidine synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine." [EC:2.5.1.16] subset: gosubset_prok synonym: "aminopropyltransferase activity" EXACT [EC:2.5.1.16] synonym: "putrescine aminopropyltransferase activity" EXACT [EC:2.5.1.16] synonym: "S-adenosylmethioninamine:putrescine 3-aminopropyltransferase activity" EXACT [EC:2.5.1.16] synonym: "SpeE" RELATED [EC:2.5.1.16] synonym: "spermidine synthetase activity" EXACT [EC:2.5.1.16] xref: EC:2.5.1.16 xref: GO:0004766 xref: MetaCyc:SPERMIDINESYN-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0001127 name: sphingomyelin phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: sphingomyelin + H2O = N-acylsphingosine + choline phosphate." [EC:3.1.4.12] subset: gosubset_prok synonym: "acid sphingomyelin phosphodiesterase" NARROW [] synonym: "acid sphingomyelinase activity" NARROW [EC:3.1.4.12] synonym: "neutral sphingomyelin phosphodiesterase" NARROW [] synonym: "neutral sphingomyelinase activity" NARROW [EC:3.1.4.12] synonym: "sphingomyelin cholinephosphohydrolase activity" EXACT [EC:3.1.4.12] synonym: "sphingomyelinase activity" EXACT [] xref: EC:3.1.4.12 xref: GO:0004767 xref: GO:0030230 xref: GO:0030231 xref: MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-RXN is_a: CCO:F0000999 ! phospholipase activity is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0001128 name: stearoyl-CoA 9-desaturase activity namespace: molecular_function def: "Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O." [EC:1.14.19.1] comment: Note that this function was formerly EC:1.14.99.5. subset: gosubset_prok synonym: "acyl-CoA desaturase activity" EXACT [EC:1.14.19.1] synonym: "delta(9)-desaturase activity" EXACT [EC:1.14.19.1] synonym: "delta9-desaturase activity" EXACT [EC:1.14.19.1] synonym: "fatty acid desaturase activity" EXACT [EC:1.14.19.1] synonym: "stearoyl-CoA desaturase activity" EXACT [] synonym: "stearoyl-CoA, hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.19.1] synonym: "stearoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (9,10-dehydrogenating)" EXACT [EC:1.14.19.1] xref: EC:1.14.19.1 xref: GO:0004768 xref: GO:0016214 xref: MetaCyc:1.14.19.1-RXN is_a: CCO:F0003300 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Term] id: CCO:F0001129 name: steroid delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid." [EC:5.3.3.1] subset: gosubset_prok synonym: "3-oxosteroid delta5-delta4-isomerase activity" EXACT [EC:5.3.3.1] synonym: "3-oxosteroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta(5)-3-keto steroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta(5)-3-ketosteroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta(5)-3-oxosteroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta(5)-steroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta5(or delta4)-3-keto steroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta5-3-keto steroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta5-3-ketosteroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta5-3-oxosteroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta5-ketosteroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "delta5-steroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "hydroxysteroid isomerase activity" EXACT [EC:5.3.3.1] synonym: "steroid D-isomerase activity" EXACT [] synonym: "steroid isomerase activity" EXACT [EC:5.3.3.1] xref: EC:5.3.3.1 xref: GO:0004769 xref: MetaCyc:STEROID-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0001130 name: sterol carrier protein X-related thiolase activity namespace: molecular_function xref: GO:0004770 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0001131 name: sterol esterase activity namespace: molecular_function def: "Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid." [EC:3.1.1.13] synonym: "acylcholesterol lipase activity" EXACT [EC:3.1.1.13] synonym: "cholesterase activity" EXACT [EC:3.1.1.13] synonym: "cholesterol ester hydrolase activity" EXACT [EC:3.1.1.13] synonym: "cholesterol ester synthase activity" NARROW [EC:3.1.1.13] synonym: "cholesterol esterase activity" NARROW [EC:3.1.1.13] synonym: "cholesteryl ester hydrolase activity" EXACT [EC:3.1.1.13] synonym: "cholesteryl ester synthase activity" EXACT [EC:3.1.1.13] synonym: "cholesteryl esterase activity" EXACT [EC:3.1.1.13] synonym: "sterol ester hydrolase activity" EXACT [EC:3.1.1.13] synonym: "steryl-ester acylhydrolase activity" EXACT [EC:3.1.1.13] synonym: "triterpenol esterase activity" EXACT [EC:3.1.1.13] xref: EC:3.1.1.13 xref: GO:0004771 xref: MetaCyc:STEROL-ESTERASE-RXN xref: Reactome:14316 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0001132 name: sterol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + cholesterol = CoA + cholesterol ester." [EC:2.3.1.26] synonym: "ACAT" EXACT [] synonym: "acyl coenzyme A-cholesterol-O-acyltransferase activity" EXACT [EC:2.3.1.26] synonym: "acyl-CoA:cholesterol acyltransferase activity" EXACT [EC:2.3.1.26] synonym: "acyl-CoA:cholesterol O-acyltransferase activity" EXACT [EC:2.3.1.26] synonym: "acylcoenzyme A:cholesterol O-acyltransferase activity" EXACT [] synonym: "cholesterol acyltransferase activity" BROAD [EC:2.3.1.26] synonym: "cholesterol ester synthetase activity" EXACT [EC:2.3.1.26] synonym: "cholesterol O-acyltransferase activity" EXACT [] synonym: "cholesteryl ester synthetase activity" EXACT [EC:2.3.1.26] synonym: "sterol-ester synthase activity" EXACT [EC:2.3.1.26] synonym: "sterol-ester synthetase activity" EXACT [EC:2.3.1.26] xref: EC:2.3.1.26 xref: GO:0004772 xref: GO:0017066 xref: MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0001133 name: steryl-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + SO4(2-) (sulfate)." [EC:3.1.6.2] synonym: "3-beta-hydroxysteroid sulfate sulfatase activity" EXACT [EC:3.1.6.2] synonym: "arylsulfatase C activity" EXACT [EC:3.1.6.2] synonym: "dehydroepiandrosterone sulfatase activity" EXACT [EC:3.1.6.2] synonym: "dehydroepiandrosterone sulfate sulfatase activity" EXACT [EC:3.1.6.2] synonym: "phenolic steroid sulfatase activity" EXACT [EC:3.1.6.2] synonym: "pregnenolone sulfatase activity" EXACT [EC:3.1.6.2] synonym: "steroid 3-sulfatase activity" EXACT [EC:3.1.6.2] synonym: "steroid sulfatase activity" EXACT [EC:3.1.6.2] synonym: "steroid sulfate sulfohydrolase activity" EXACT [EC:3.1.6.2] synonym: "sterol sulfatase activity" EXACT [EC:3.1.6.2] synonym: "steryl-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.2] synonym: "steryl-sulphatase activity" EXACT [] xref: EC:3.1.6.2 xref: GO:0004773 xref: MetaCyc:STERYL-SULFATASE-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0001134 name: succinate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction between succinate and CoA to form succinyl-CoA." [EC:6.2.1.-, GOC:ai] subset: gosubset_prok xref: EC:6.2.1.- xref: GO:0004774 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0001135 name: succinate-CoA ligase (ADP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate." [EC:6.2.1.5] subset: gosubset_prok synonym: "A-SCS" RELATED [EC:6.2.1.5] synonym: "A-STK (adenin nucleotide-linked succinate thiokinase)" RELATED [EC:6.2.1.5] synonym: "succinate thiokinase activity" EXACT [EC:6.2.1.5] synonym: "succinate:CoA ligase (ADP-forming) activity" EXACT [EC:6.2.1.5] synonym: "succinic thiokinase" BROAD [EC:6.2.1.5] synonym: "succinyl coenzyme A synthetase" BROAD [EC:6.2.1.5] synonym: "succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity" EXACT [EC:6.2.1.5] synonym: "succinyl-CoA synthetase (ADP-forming) activity" EXACT [EC:6.2.1.5] synonym: "succinyl-CoA synthetase activity" EXACT [EC:6.2.1.5] xref: EC:6.2.1.5 xref: GO:0004775 xref: MetaCyc:SUCCCOASYN-RXN xref: Reactome:14321 is_a: CCO:F0001134 ! succinate-CoA ligase activity [Term] id: CCO:F0001136 name: succinate-CoA ligase (GDP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate." [EC:6.2.1.4] subset: gosubset_prok synonym: "G-STK" RELATED [EC:6.2.1.4] synonym: "P-enzyme" RELATED [EC:6.2.1.4] synonym: "SCS" RELATED [EC:6.2.1.4] synonym: "succinate-phosphorylating enzyme" RELATED [EC:6.2.1.4] synonym: "succinate:CoA ligase (GDP-forming) activity" EXACT [EC:6.2.1.4] synonym: "succinic thiokinase" BROAD [EC:6.2.1.4] synonym: "succinyl CoA synthetase activity" EXACT [EC:6.2.1.4] synonym: "succinyl coenzyme A synthetase" BROAD [EC:6.2.1.4] synonym: "succinyl coenzyme A synthetase (GDP-forming) activity" EXACT [EC:6.2.1.4] synonym: "succinyl coenzyme A synthetase (guanosine diphosphate-forming) activity" EXACT [EC:6.2.1.4] synonym: "succinyl-CoA synthetase (GDP-forming) activity" EXACT [EC:6.2.1.4] xref: EC:6.2.1.4 xref: GO:0004776 xref: MetaCyc:SUCCINATE--COA-LIGASE-(GDP-FORMING)-RXN xref: Reactome:14322 is_a: CCO:F0001134 ! succinate-CoA ligase activity [Term] id: CCO:F0001137 name: succinate-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+." [EC:1.2.1.24] subset: gosubset_prok synonym: "succinate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.24] synonym: "succinate semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.24] synonym: "succinate-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.24] synonym: "succinic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.24] synonym: "succinyl semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.24] xref: EC:1.2.1.24 xref: GO:0004777 xref: GO:0008952 xref: MetaCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001138 name: succinyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + H2O = CoA + succinate." [EC:3.1.2.3] synonym: "succinyl coenzyme A deacylase activity" EXACT [EC:3.1.2.3] synonym: "succinyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.3] synonym: "succinyl-CoA acylase activity" EXACT [EC:3.1.2.3] xref: EC:3.1.2.3 xref: GO:0004778 xref: MetaCyc:SUCCINYL-COA-HYDROLASE-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0001139 name: sulfate adenylyltransferase activity namespace: molecular_function subset: gosubset_prok synonym: "sulphate adenylyltransferase activity" EXACT [] xref: EC:2.7.7.- xref: GO:0004779 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0001140 name: sulfate adenylyltransferase (ADP) activity namespace: molecular_function def: "Catalysis of the reaction: ADP + SO4(2-) (sulfate) = phosphate + adenylylsulfate." [EC:2.7.7.5] synonym: "adenosine diphosphate sulfurylase activity" EXACT [EC:2.7.7.5] synonym: "ADP-sulfurylase activity" EXACT [EC:2.7.7.5] synonym: "ADP:sulfate adenylyltransferase activity" EXACT [] synonym: "sulfate (adenosine diphosphate) adenylyltransferase activity" EXACT [EC:2.7.7.5] synonym: "sulphate adenylyltransferase (ADP) activity" EXACT [] xref: EC:2.7.7.5 xref: GO:0004780 xref: MetaCyc:SULFATE-ADENYLYLTRANSFERASE-(ADP)-RXN is_a: CCO:F0001139 ! sulfate adenylyltransferase activity [Term] id: CCO:F0001141 name: sulfate adenylyltransferase (ATP) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + SO4(2-) (sulfate) = diphosphate + adenylylsulfate." [EC:2.7.7.4] subset: gosubset_prok synonym: "adenosine-5'-triphosphate sulfurylase activity" EXACT [EC:2.7.7.4] synonym: "adenosinetriphosphate sulfurylase activity" EXACT [EC:2.7.7.4] synonym: "adenylylsulfate pyrophosphorylase activity" EXACT [EC:2.7.7.4] synonym: "ATP sulfurylase activity" EXACT [EC:2.7.7.4] synonym: "ATP-sulfurylase activity" EXACT [EC:2.7.7.4] synonym: "ATP:sulfate adenylyltransferase activity" EXACT [] synonym: "sulfate adenylate transferase activity" EXACT [EC:2.7.7.4] synonym: "sulfurylase activity" RELATED [EC:2.7.7.4] synonym: "sulphate adenylyltransferase (ATP) activity" EXACT [] xref: EC:2.7.7.4 xref: GO:0004781 xref: MetaCyc:SULFATE-ADENYLYLTRANS-RXN xref: Reactome:14341 is_a: CCO:F0001139 ! sulfate adenylyltransferase activity [Term] id: CCO:F0001142 name: sulfinoalanine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2." [EC:4.1.1.29] synonym: "3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)" EXACT [EC:4.1.1.29] synonym: "3-sulfino-L-alanine carboxy-lyase activity" EXACT [EC:4.1.1.29] synonym: "CADCase/CSADCase activity" EXACT [EC:4.1.1.29] synonym: "CSAD" RELATED [EC:4.1.1.29] synonym: "CSADCase activity" EXACT [EC:4.1.1.29] synonym: "cysteic decarboxylase activity" EXACT [EC:4.1.1.29] synonym: "cysteine-sulfinate decarboxylase activity" EXACT [EC:4.1.1.29] synonym: "cysteinesulfinate decarboxylase activity" EXACT [EC:4.1.1.29] synonym: "cysteinesulfinic acid decarboxylase activity" EXACT [EC:4.1.1.29] synonym: "L-cysteinesulfinic acid decarboxylase activity" EXACT [EC:4.1.1.29] synonym: "sulfoalanine decarboxylase activity" EXACT [EC:4.1.1.29] synonym: "sulphinoalanine decarboxylase activity" EXACT [] xref: EC:4.1.1.29 xref: GO:0004782 xref: MetaCyc:SULFINOALANINE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0001143 name: sulfite reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: H2S + 3 NADP+ + 3 H2O = SO3(2-) (sulfite) + 3 NADPH + 3 H+." [EC:1.8.1.2] subset: gosubset_prok synonym: "H2S-NADP oxidoreductase activity" EXACT [EC:1.8.1.2] synonym: "hydrogen-sulfide:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.2] synonym: "NADPH-dependent sulfite reductase activity" EXACT [EC:1.8.1.2] synonym: "NADPH-sulfite reductase activity" EXACT [EC:1.8.1.2] synonym: "NADPH:sulfite reductase flavoprotein" RELATED [] synonym: "sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.8.1.2] synonym: "sulphite reductase (NADPH) activity" EXACT [] xref: EC:1.8.1.2 xref: GO:0004783 xref: MetaCyc:SULFITE-REDUCT-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001144 name: superoxide dismutase activity namespace: molecular_function def: "Catalysis of the reaction: 2 peroxide radical + 2 H+ = O2 + H2O2." [EC:1.15.1.1] subset: gosubset_prok synonym: "copper, zinc superoxide dismutase activity" NARROW [] synonym: "Cu,Zn-SOD" RELATED [EC:1.15.1.1] synonym: "Cu-Zn superoxide dismutase activity activity" NARROW [EC:1.15.1.1] synonym: "cuprein" RELATED [EC:1.15.1.1] synonym: "cytocuprein" RELATED [EC:1.15.1.1] synonym: "erythrocuprein" RELATED [EC:1.15.1.1] synonym: "Fe-SOD" RELATED [EC:1.15.1.1] synonym: "ferrisuperoxide dismutase activity" NARROW [EC:1.15.1.1] synonym: "hemocuprein" RELATED [EC:1.15.1.1] synonym: "hepatocuprein" RELATED [EC:1.15.1.1] synonym: "iron superoxide dismutase activity" NARROW [] synonym: "iron superoxide oxidoreductase" RELATED [] synonym: "manganese superoxide dismutase activity" NARROW [] synonym: "manganese superoxide oxidoreductase" RELATED [] synonym: "Mn, Fe superoxide dismutase" NARROW [] synonym: "Mn-SOD" RELATED [EC:1.15.1.1] synonym: "nickel superoxide dismutase activity" NARROW [] synonym: "nickel superoxide oxidoreductase" RELATED [] synonym: "SOD" RELATED [EC:1.15.1.1] synonym: "SOD-1" RELATED [EC:1.15.1.1] synonym: "SOD-2" RELATED [EC:1.15.1.1] synonym: "SOD-3" RELATED [EC:1.15.1.1] synonym: "SOD-4" RELATED [EC:1.15.1.1] synonym: "SODF" RELATED [EC:1.15.1.1] synonym: "SODS" RELATED [EC:1.15.1.1] synonym: "superoxide dismutase I" RELATED [EC:1.15.1.1] synonym: "superoxide dismutase II" RELATED [EC:1.15.1.1] synonym: "superoxide:superoxide oxidoreductase activity" EXACT [] synonym: "zinc superoxide oxidoreductase" RELATED [] xref: EC:1.15.1.1 xref: GO:0004784 xref: GO:0004785 xref: GO:0008382 xref: GO:0008383 xref: GO:0016954 xref: MetaCyc:SUPEROX-DISMUT-RXN is_a: CCO:F0003303 ! oxidoreductase activity, acting on superoxide radicals as acceptor [Term] id: CCO:F0001145 name: thiamin-pyrophosphatase activity namespace: molecular_function def: "Catalysis of the reaction: TDP + H2O = TMP + phosphate." [EC:3.6.1.-, GOC:ai] synonym: "thiamin pyrophosphatase activity" EXACT [] synonym: "thiamine pyrophosphatase activity" EXACT [] synonym: "thiaminpyrophosphatase activity" EXACT [EC:3.6.1.6] synonym: "TPPase activity" EXACT [] xref: EC:3.6.1.- xref: GO:0004787 is_a: CCO:F0003573 ! nucleoside-diphosphatase activity [Term] id: CCO:F0001146 name: thiamin diphosphokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + thiamin = AMP + thiamin diphosphate." [EC:2.7.6.2] subset: gosubset_prok synonym: "ATP:thiamin pyrophosphotransferase activity" EXACT [EC:2.7.6.2] synonym: "ATP:thiamine diphosphotransferase activity" EXACT [EC:2.7.6.2] synonym: "thiamin pyrophosphokinase activity" EXACT [] synonym: "thiamin pyrophosphotransferase activity" EXACT [EC:2.7.6.2] synonym: "thiamin:ATP pyrophosphotransferase activity" EXACT [EC:2.7.6.2] synonym: "thiamine diphosphokinase activity" EXACT [EC:2.7.6.2] synonym: "thiamine pyrophosphokinase activity" EXACT [] synonym: "thiaminokinase activity" EXACT [EC:2.7.6.2] synonym: "TPTase activity" EXACT [EC:2.7.6.2] xref: EC:2.7.6.2 xref: GO:0004788 xref: MetaCyc:THIAMIN-PYROPHOSPHOKINASE-RXN is_a: CCO:F0003350 ! diphosphotransferase activity [Term] id: CCO:F0001147 name: thiamin-phosphate diphosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-4-methyl-5-(2-phosphonooxyethyl)-thiazole = diphosphate + thiamin monophosphate." [EC:2.5.1.3] subset: gosubset_prok synonym: "2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)thiazole 2-methyl-4-aminopyrimidine-5-methenyltransferase activity" EXACT [EC:2.5.1.3] synonym: "thiamin-phosphate pyrophosphorylase activity" EXACT [] synonym: "thiamine monophosphate pyrophosphorylase activity" EXACT [EC:2.5.1.3] synonym: "thiamine phosphate pyrophosphorylase activity" EXACT [EC:2.5.1.3] synonym: "thiamine-phosphate diphosphorylase activity" EXACT [EC:2.5.1.3] synonym: "thiamine-phosphate pyrophosphorylase activity" EXACT [] synonym: "thiamine-phosphate synthase activity" EXACT [EC:2.5.1.3] synonym: "TMP diphosphorylase activity" EXACT [EC:2.5.1.3] synonym: "TMP pyrophosphorylase activity" EXACT [EC:2.5.1.3] synonym: "TMP-PPase activity" EXACT [EC:2.5.1.3] xref: EC:2.5.1.3 xref: GO:0004789 xref: MetaCyc:THI-P-SYN-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0001148 name: thioether S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium." [EC:2.1.1.96] synonym: "S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase activity" EXACT [EC:2.1.1.96] synonym: "S-adenosyl-L-methionine:thioether S-methyltransferase activity" EXACT [EC:2.1.1.96] synonym: "thioether methyltransferase activity" EXACT [EC:2.1.1.96] xref: EC:2.1.1.96 xref: GO:0004790 xref: MetaCyc:THIOETHER-S-METHYLTRANSFERASE-RXN is_a: CCO:F0001759 ! S-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001149 name: thioredoxin-disulfide reductase activity namespace: molecular_function def: "Catalysis of the reaction: thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+." [EC:1.8.1.9, ISBN:0198547684] subset: gosubset_prok synonym: "NADP--thioredoxin reductase activity" EXACT [EC:1.8.1.9] synonym: "NADPH--thioredoxin reductase activity" EXACT [EC:1.8.1.9] synonym: "NADPH2:oxidized thioredoxin oxidoreductase activity" EXACT [EC:1.8.1.9] synonym: "NADPH:oxidized thioredoxin oxidoreductase activity" EXACT [EC:1.8.1.9] synonym: "thioredoxin disulfide reductase activity" EXACT [] synonym: "thioredoxin reductase (NADPH) activity" EXACT [] synonym: "thioredoxin-disulphide reductase activity" EXACT [] synonym: "thioredoxin:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.9] xref: EC:1.8.1.9 xref: GO:0004791 xref: MetaCyc:THIOREDOXIN-REDUCT-NADPH-RXN xref: Reactome:14367 is_a: CCO:F0003069 ! antioxidant activity is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001150 name: thiosulfate sulfurtransferase activity namespace: molecular_function def: "Catalysis of the reaction: thiosulfate + cyanide = SO3(2-) (sulfite) + thiocyanate." [EC:2.8.1.1] subset: gosubset_prok synonym: "rhodanase activity" EXACT [EC:2.8.1.1] synonym: "rhodanese activity" RELATED [EC:2.8.1.1] synonym: "thiosulfate cyanide transsulfurase activity" EXACT [EC:2.8.1.1] synonym: "thiosulfate thiotransferase activity" EXACT [EC:2.8.1.1] synonym: "thiosulfate:cyanide sulfurtransferase activity" EXACT [EC:2.8.1.1] synonym: "thiosulphate sulphurtransferase activity" EXACT [] xref: EC:2.8.1.1 xref: GO:0004792 xref: MetaCyc:THIOSULFATE-SULFURTRANSFERASE-RXN is_a: CCO:F0003355 ! sulfurtransferase activity [Term] id: CCO:F0001151 name: threonine aldolase activity namespace: molecular_function def: "Catalysis of the reaction: L-threonine = glycine + acetaldehyde." [EC:4.1.2.5] subset: gosubset_prok synonym: "L-threonine acetaldehyde-lyase (glycine-forming)" EXACT [EC:4.1.2.5] synonym: "L-threonine acetaldehyde-lyase activity" EXACT [EC:4.1.2.5] synonym: "L-threonine aldolase activity" EXACT [] xref: EC:4.1.2.5 xref: GO:0004793 xref: MetaCyc:THREONINE-ALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0001152 name: L-threonine ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3." [EC:4.3.1.19] comment: Note that this function was formerly EC:4.2.1.16. subset: gosubset_prok synonym: "L-serine dehydratase activity" RELATED [EC:4.3.1.19] synonym: "L-threonine ammonia-lyase (2-oxobutanoate-forming)" EXACT [EC:4.3.1.19] synonym: "L-threonine deaminase activity" EXACT [EC:4.3.1.19] synonym: "L-threonine dehydratase activity" EXACT [EC:4.3.1.19] synonym: "L-threonine hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.19] synonym: "serine deaminase activity" RELATED [EC:4.3.1.19] synonym: "threonine ammonia-lyase activity" EXACT [] synonym: "threonine deaminase activity" EXACT [EC:4.3.1.19] synonym: "threonine dehydrase activity" EXACT [EC:4.3.1.19] synonym: "threonine dehydratase activity" EXACT [] xref: EC:4.3.1.19 xref: GO:0004794 xref: MetaCyc:THREDEHYD-RXN xref: UM-BBD_enzymeID:e0306 is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0001153 name: threonine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate." [EC:4.2.3.1] subset: gosubset_prok synonym: "O-phospho-L-homoserine phospho-lyase (adding water)" EXACT [EC:4.2.3.1] synonym: "O-phospho-L-homoserine phospho-lyase (adding water; L-threonine-forming)" EXACT [EC:4.2.3.1] synonym: "threonine synthetase activity" EXACT [EC:4.2.3.1] xref: EC:4.2.3.1 xref: GO:0004795 xref: MetaCyc:THRESYN-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0001154 name: thromboxane-A synthase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-9-alpha,11-alpha-epoxy-15-hydroxythromba-5,13-dienoate." [EC:5.3.99.5] synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity" EXACT [EC:5.3.99.5] synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity" EXACT [EC:5.3.99.5] synonym: "cytochrome P450 CYP5" NARROW [] synonym: "thromboxane synthase activity" EXACT [EC:5.3.99.5] synonym: "thromboxane synthetase activity" EXACT [EC:5.3.99.5] xref: EC:5.3.99.5 xref: GO:0004796 xref: GO:0008400 xref: MetaCyc:THROMBOXANE-A-SYNTHASE-RXN xref: Reactome:14373 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0001155 name: thymidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate." [EC:2.7.1.21] subset: gosubset_prok synonym: "2'-deoxythymidine kinase activity" EXACT [EC:2.7.1.21] synonym: "ATP:thymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.21] synonym: "deoxythymidine kinase (phosphorylating)" EXACT [EC:2.7.1.21] synonym: "thymidine kinase (phosphorylating)" EXACT [EC:2.7.1.21] xref: EC:2.7.1.21 xref: GO:0004797 xref: MetaCyc:THYKI-RXN is_a: CCO:F0004072 ! deoxynucleoside kinase activity [Term] id: CCO:F0001156 name: thymidylate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate." [EC:2.7.4.9] subset: gosubset_prok synonym: "ATP:dTMP phosphotransferase activity" EXACT [EC:2.7.4.9] synonym: "deoxythymidine 5'-monophosphate kinase activity" EXACT [EC:2.7.4.9] synonym: "dTMP kinase activity" EXACT [] synonym: "thymidine 5'-monophosphate kinase activity" EXACT [EC:2.7.4.9] synonym: "thymidine monophosphate kinase activity" EXACT [EC:2.7.4.9] synonym: "thymidylate monophosphate kinase activity" EXACT [EC:2.7.4.9] synonym: "thymidylic acid kinase activity" EXACT [EC:2.7.4.9] synonym: "thymidylic kinase activity" EXACT [EC:2.7.4.9] synonym: "TMPK activity" EXACT [EC:2.7.4.9] xref: EC:2.7.4.9 xref: GO:0004798 xref: MetaCyc:DTMPKI-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004124 ! nucleotide kinase activity [Term] id: CCO:F0001157 name: thymidylate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP." [EC:2.1.1.45] subset: gosubset_prok synonym: "5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity" EXACT [EC:2.1.1.45] synonym: "dTMP synthase activity" EXACT [EC:2.1.1.45] synonym: "methylenetetrahydrofolate:dUMP C-methyltransferase activity" EXACT [EC:2.1.1.45] synonym: "thymidylate synthetase activity" EXACT [EC:2.1.1.45] synonym: "TMP synthetase activity" EXACT [EC:2.1.1.45] xref: EC:2.1.1.45 xref: GO:0004799 xref: MetaCyc:THYMIDYLATESYN-RXN xref: Reactome:14376 is_a: CCO:F0005619 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity [Term] id: CCO:F0001158 name: thyroxine 5'-deiodinase activity namespace: molecular_function def: "Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2." [EC:1.97.1.10] comment: Note that this was EC:3.8.1.4. synonym: "acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)" EXACT [EC:1.97.1.10] synonym: "diiodothyronine 5'-deiodinase activity" EXACT [EC:1.97.1.10] synonym: "iodothyronine 5'-deiodinase activity" EXACT [EC:1.97.1.10] synonym: "iodothyronine outer ring monodeiodinase activity" EXACT [EC:1.97.1.10] synonym: "L-thyroxine iodohydrolase (reducing) activity" EXACT [EC:1.97.1.10] synonym: "thyroxine 5' deiodinase activity" EXACT [] synonym: "thyroxine deiodinase activity" BROAD [] synonym: "type I iodothyronine deiodinase activity" NARROW [EC:1.97.1.10] synonym: "type II iodothyronine deiodinase activity" NARROW [EC:1.97.1.10] xref: EC:1.97.1.10 xref: GO:0004800 xref: MetaCyc:THYROXINE-DEIODINASE-RXN is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0001159 name: transaldolase activity namespace: molecular_function def: "Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate." [EC:2.2.1.2] subset: gosubset_prok synonym: "dihydroxyacetone transferase activity" EXACT [EC:2.2.1.2] synonym: "dihydroxyacetonetransferase activity" EXACT [EC:2.2.1.2] synonym: "glycerone transferase activity" EXACT [EC:2.2.1.2] synonym: "sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity" EXACT [EC:2.2.1.2] xref: EC:2.2.1.2 xref: GO:0004801 xref: MetaCyc:TRANSALDOL-RXN xref: Reactome:15049 is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0001160 name: transketolase activity namespace: molecular_function def: "Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate." [EC:2.2.1.1] subset: gosubset_prok synonym: "glycoaldehyde transferase activity" EXACT [EC:2.2.1.1] synonym: "glycolaldehydetransferase activity" EXACT [EC:2.2.1.1] synonym: "sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity" EXACT [EC:2.2.1.1] xref: EC:2.2.1.1 xref: GO:0004802 xref: MetaCyc:1TRANSKETO-RXN xref: Reactome:15050 is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0001161 name: transposase activity namespace: molecular_function def: "Catalysis of the transposition of transposable elements or transposons. Transposases are involved in site-specific DNA recombination required for transposition in bacteria and other organisms." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0004803 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0001162 name: P-element encoded transposase activity namespace: molecular_function xref: GO:0004804 is_a: CCO:F0001161 ! transposase activity [Term] id: CCO:F0001163 name: trehalose-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate." [EC:3.1.3.12] subset: gosubset_prok synonym: "trehalose 6-phosphatase activity" EXACT [EC:3.1.3.12] synonym: "trehalose 6-phosphate phosphatase activity" EXACT [EC:3.1.3.12] synonym: "trehalose phosphatase activity" EXACT [] synonym: "trehalose-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.12] xref: EC:3.1.3.12 xref: GO:0004805 xref: MetaCyc:TREHALOSEPHOSPHA-RXN is_a: CCO:F0004126 ! carbohydrate phosphatase activity [Term] id: CCO:F0001164 name: triacylglycerol lipase activity namespace: molecular_function def: "Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a fatty acid anion." [EC:3.1.1.3] subset: gosubset_prok synonym: "amano AP" RELATED [EC:3.1.1.3] synonym: "amano B" RELATED [EC:3.1.1.3] synonym: "amano CE" RELATED [EC:3.1.1.3] synonym: "amano CES" RELATED [EC:3.1.1.3] synonym: "amano P" RELATED [EC:3.1.1.3] synonym: "amno N-AP" RELATED [EC:3.1.1.3] synonym: "butyrinase activity" EXACT [EC:3.1.1.3] synonym: "cacordase activity" EXACT [EC:3.1.1.3] synonym: "capalase L" RELATED [EC:3.1.1.3] synonym: "GA 56" RELATED [EC:3.1.1.3] synonym: "GEH" RELATED [EC:3.1.1.3] synonym: "glycerol ester hydrolase activity" EXACT [EC:3.1.1.3] synonym: "glycerol-ester hydrolase activity" EXACT [EC:3.1.1.3] synonym: "heparin releasable hepatic lipase" NARROW [EC:3.1.1.3] synonym: "hepatic lipase" NARROW [EC:3.1.1.3] synonym: "hepatic monoacylglycerol acyltransferase" NARROW [EC:3.1.1.3] synonym: "lipazin" RELATED [EC:3.1.1.3] synonym: "liver lipase" NARROW [EC:3.1.1.3] synonym: "meito MY 30" RELATED [EC:3.1.1.3] synonym: "meito sangyo OF lipase" RELATED [EC:3.1.1.3] synonym: "post-heparin plasma protamine-resistant lipase" NARROW [EC:3.1.1.3] synonym: "PPL" RELATED [EC:3.1.1.3] synonym: "salt-resistant post-heparin lipase" NARROW [EC:3.1.1.3] synonym: "steapsin" RELATED [EC:3.1.1.3] synonym: "takedo 1969-4-9" RELATED [EC:3.1.1.3] synonym: "triacetinase activity" EXACT [EC:3.1.1.3] synonym: "triacylglycerol acylhydrolase activity" EXACT [EC:3.1.1.3] synonym: "triacylglycerol ester hydrolase activity" EXACT [EC:3.1.1.3] synonym: "tributyrase activity" RELATED [EC:3.1.1.3] synonym: "tributyrin esterase activity" EXACT [EC:3.1.1.3] synonym: "tributyrinase activity" EXACT [EC:3.1.1.3] synonym: "triglyceridase activity" EXACT [EC:3.1.1.3] synonym: "triglyceride hydrolase activity" EXACT [EC:3.1.1.3] synonym: "triglyceride lipase activity" EXACT [EC:3.1.1.3] synonym: "triolein hydrolase activity" EXACT [EC:3.1.1.3] synonym: "tween hydrolase activity" EXACT [EC:3.1.1.3] synonym: "tween-hydrolyzing esterase activity" EXACT [EC:3.1.1.3] synonym: "tweenase activity" EXACT [EC:3.1.1.3] synonym: "tweenesterase activity" EXACT [EC:3.1.1.3] xref: EC:3.1.1.3 xref: GO:0004806 xref: MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN xref: Reactome:15058 is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0003111 ! lipase activity [Term] id: CCO:F0001165 name: triose-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate." [EC:5.3.1.1] subset: gosubset_prok synonym: "D-glyceraldehyde-3-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.1] synonym: "D-glyceraldehyde-3-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.1] synonym: "phosphotriose isomerase activity" EXACT [EC:5.3.1.1] synonym: "triose phosphate mutase activity" EXACT [EC:5.3.1.1] synonym: "triose phosphoisomerase activity" EXACT [EC:5.3.1.1] synonym: "triosephosphate isomerase activity" EXACT [EC:5.3.1.1] synonym: "triosephosphate mutase activity" EXACT [EC:5.3.1.1] xref: EC:5.3.1.1 xref: GO:0004807 xref: MetaCyc:TRIOSEPISOMERIZATION-RXN xref: Reactome:70450 is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0001166 name: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate." [EC:2.1.1.61] subset: gosubset_prok synonym: "S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase activity" EXACT [EC:2.1.1.61] synonym: "transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase activity" EXACT [EC:2.1.1.61] synonym: "tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase activity" EXACT [EC:2.1.1.61] xref: EC:2.1.1.61 xref: GO:0004808 xref: GO:0016425 xref: MetaCyc:2.1.1.61-RXN is_a: CCO:F0001762 ! tRNA methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001167 name: tRNA (guanine-N2-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine." [EC:2.1.1.32] subset: gosubset_prok synonym: "guanine-N2-methylase activity" EXACT [EC:2.1.1.32] synonym: "N(2),N(2)-dimethylguanine tRNA methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "N2,N2-dimethylguanine tRNA methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "S-adenosyl-L-methionine:tRNA (guanine-2-N-)-methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "transfer ribonucleate guanine 2-methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "transfer ribonucleate guanine N2-methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "transfer RNA guanine 2-methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "tRNA 2,2-dimethylguanosine-26 methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "tRNA(guanine-26,N(2)-N(2)) methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "tRNA(guanine-26,N2-N2) methyltransferase activity" EXACT [EC:2.1.1.32] synonym: "tRNA(m(2,2)G26)dimethyltransferase activity" EXACT [EC:2.1.1.32] xref: EC:2.1.1.32 xref: GO:0004809 xref: MetaCyc:TRNA-(GUANINE-N2-)-METHYLTRANSFERASE-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0003146 ! tRNA (guanine) methyltransferase activity [Term] id: CCO:F0001168 name: tRNA adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1)." [EC:2.7.7.25] subset: gosubset_prok synonym: "-C-C-A pyrophosphorylase" BROAD [EC:2.7.7.25] synonym: "ATP (CTP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.25] synonym: "ATP(CTP)-tRNA nucleotidyltransferase" BROAD [EC:2.7.7.25] synonym: "ATP:tRNA adenylyltransferase activity" EXACT [] synonym: "CCA-adding enzyme activity" RELATED [EC:2.7.7.25] synonym: "CTP(ATP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.25] synonym: "ribonucleic cytidylic cytidylic adenylic pyrophosphorylase" BROAD [EC:2.7.7.25] synonym: "ribonucleic cytidylyltransferase" BROAD [EC:2.7.7.25] synonym: "transfer ribonucleate adenyltransferase activity" EXACT [EC:2.7.7.25] synonym: "transfer ribonucleate adenylyltransferase" BROAD [EC:2.7.7.25] synonym: "transfer ribonucleate cytidylyltransferase" BROAD [EC:2.7.7.25] synonym: "transfer ribonucleate nucleotidyltransferase" BROAD [EC:2.7.7.25] synonym: "transfer ribonucleic acid nucleotidyl transferase" BROAD [EC:2.7.7.25] synonym: "transfer ribonucleic adenylyl (cytidylyl) transferase" BROAD [EC:2.7.7.25] synonym: "transfer ribonucleic-terminal trinucleotide nucleotidyltransferase" BROAD [EC:2.7.7.25] synonym: "transfer RNA adenylyltransferase" BROAD [EC:2.7.7.25] synonym: "transfer-RNA nucleotidyltransferase" BROAD [EC:2.7.7.25] synonym: "tRNA adenylyl(cytidylyl)transferase" BROAD [EC:2.7.7.25] synonym: "tRNA CCA-diphosphorylase activity" RELATED [EC:2.7.7.25] synonym: "tRNA CCA-pyrophosphorylase activity" RELATED [EC:2.7.7.25] synonym: "tRNA-nucleotidyltransferase activity" BROAD [EC:2.7.7.25] xref: EC:2.7.7.25 xref: GO:0004810 xref: MetaCyc:TRNA-ADENYLYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0001169 name: tRNA isopentenyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: isopentenyl diphosphate + tRNA = diphosphate + tRNA containing 6-isopentenyladenosine." [EC:2.5.1.8] subset: gosubset_prok synonym: "delta2-isopentenyl pyrophosphate:transfer ribonucleic acid delta2-isopentenyltransferase activity" EXACT [EC:2.5.1.8] synonym: "delta2-isopentenyl pyrophosphate:tRNA-delta2-isopentenyl transferase activity" EXACT [EC:2.5.1.8] synonym: "IPP transferase activity" EXACT [EC:2.5.1.8] synonym: "isopentenyl-diphosphate:tRNA isopentenyltransferase activity" EXACT [EC:2.5.1.8] synonym: "transfer ribonucleate isopentenyltransferase activity" EXACT [EC:2.5.1.8] xref: EC:2.5.1.8 xref: GO:0004811 xref: MetaCyc:TRNA-ISOPENTENYLTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0001170 name: aminoacyl-tRNA ligase activity namespace: molecular_function def: "Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that the bond resulting from this reaction is an carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA. subset: gosubset_prok synonym: "aminoacyl-tRNA synthetase activity" EXACT [GOC:hjd] xref: EC:6.1.1.- xref: GO:0004812 is_a: CCO:F0003435 ! ligase activity, forming aminoacyl-tRNA and related compounds [Term] id: CCO:F0001171 name: alanine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)." [EC:6.1.1.7] subset: gosubset_prok synonym: "Ala-tRNA synthetase activity" EXACT [EC:6.1.1.7] synonym: "alanine transfer RNA synthetase activity" EXACT [EC:6.1.1.7] synonym: "alanine translase activity" EXACT [EC:6.1.1.7] synonym: "alanine tRNA synthetase activity" EXACT [EC:6.1.1.7] synonym: "alanine-transfer RNA ligase activity" EXACT [EC:6.1.1.7] synonym: "alanyl-transfer ribonucleate synthase activity" EXACT [EC:6.1.1.7] synonym: "alanyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.7] synonym: "alanyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.7] synonym: "alanyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.7] synonym: "alanyl-tRNA synthetase activity" EXACT [] synonym: "AlaRS" RELATED [EC:6.1.1.7] synonym: "L-alanine:tRNAAla ligase (AMP-forming)" EXACT [EC:6.1.1.7] xref: EC:6.1.1.7 xref: GO:0004813 xref: MetaCyc:ALANINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001172 name: arginine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)." [EC:6.1.1.19] subset: gosubset_prok synonym: "arginine translase activity" EXACT [EC:6.1.1.19] synonym: "arginine-tRNA synthetase activity" EXACT [EC:6.1.1.19] synonym: "arginyl transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.19] synonym: "arginyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.19] synonym: "arginyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.19] synonym: "arginyl-tRNA synthetase activity" EXACT [] synonym: "L-arginine:tRNAArg ligase (AMP-forming)" EXACT [EC:6.1.1.19] xref: EC:6.1.1.19 xref: GO:0004814 xref: MetaCyc:ARGININE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001173 name: aspartate-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)." [EC:6.1.1.12] subset: gosubset_prok synonym: "aspartic acid translase activity" EXACT [EC:6.1.1.12] synonym: "aspartyl ribonucleate synthetase activity" EXACT [EC:6.1.1.12] synonym: "aspartyl ribonucleic synthetase activity" EXACT [EC:6.1.1.12] synonym: "aspartyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.12] synonym: "aspartyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.12] synonym: "aspartyl-tRNA synthetase activity" EXACT [] synonym: "L-aspartate:tRNAAsp ligase (AMP-forming)" EXACT [EC:6.1.1.12] xref: EC:6.1.1.12 xref: GO:0004815 xref: MetaCyc:ASPARTATE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001174 name: asparagine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn)." [EC:6.1.1.22] subset: gosubset_prok synonym: "asparagine translase activity" EXACT [EC:6.1.1.22] synonym: "asparaginyl transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.22] synonym: "asparaginyl transfer RNA synthetase activity" EXACT [EC:6.1.1.22] synonym: "asparaginyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.22] synonym: "asparaginyl-tRNA synthetase activity" EXACT [] synonym: "asparagyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.22] synonym: "L-asparagine:tRNAAsn ligase (AMP-forming)" EXACT [EC:6.1.1.22] xref: EC:6.1.1.22 xref: GO:0004816 xref: MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001175 name: cysteine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)." [EC:6.1.1.16] subset: gosubset_prok synonym: "cysteine translase activity" EXACT [EC:6.1.1.16] synonym: "cysteinyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.16] synonym: "cysteinyl-transferRNA synthetase activity" EXACT [EC:6.1.1.16] synonym: "cysteinyl-tRNA synthetase activity" EXACT [] synonym: "L-cysteine:tRNACys ligase (AMP-forming)" EXACT [EC:6.1.1.16] xref: EC:6.1.1.16 xref: GO:0004817 xref: MetaCyc:CYSTEINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001176 name: glutamate-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)." [EC:6.1.1.17] subset: gosubset_prok synonym: "glutamate-tRNA synthetase activity" EXACT [EC:6.1.1.17] synonym: "glutamic acid translase activity" EXACT [EC:6.1.1.17] synonym: "glutamyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.17] synonym: "glutamyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.17] synonym: "glutamyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.17] synonym: "glutamyl-tRNA synthetase activity" EXACT [] synonym: "L-glutamate:tRNAGlu ligase (AMP-forming) activity" EXACT [EC:6.1.1.17] xref: EC:6.1.1.17 xref: GO:0004818 xref: MetaCyc:GLURS-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001177 name: glutamine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)." [EC:6.1.1.18] subset: gosubset_prok synonym: "GlnRS" RELATED [EC:6.1.1.18] synonym: "glutamine translase activity" EXACT [EC:6.1.1.18] synonym: "glutamine-tRNA synthetase activity" EXACT [EC:6.1.1.18] synonym: "glutaminyl ribonucleic acid" RELATED [EC:6.1.1.18] synonym: "glutaminyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.18] synonym: "glutaminyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.18] synonym: "glutaminyl-tRNA synthetase activity" EXACT [] synonym: "L-glutamine:tRNAGln ligase (AMP-forming)" EXACT [EC:6.1.1.18] xref: EC:6.1.1.18 xref: GO:0004819 xref: MetaCyc:GLUTAMINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001178 name: glycine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)." [EC:6.1.1.14] subset: gosubset_prok synonym: "glycine:tRNAGly ligase (AMP-forming) activity" EXACT [EC:6.1.1.14] synonym: "glycyl translase activity" EXACT [EC:6.1.1.14] synonym: "glycyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.14] synonym: "glycyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.14] synonym: "glycyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.14] synonym: "glycyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.14 xref: GO:0004820 xref: MetaCyc:GLYCINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001179 name: histidine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His)." [EC:6.1.1.21] subset: gosubset_prok synonym: "histidine translase activity" EXACT [EC:6.1.1.21] synonym: "histidyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.21] synonym: "histidyl-tRNA synthetase activity" EXACT [] synonym: "L-histidine:tRNAHis ligase (AMP-forming)" EXACT [EC:6.1.1.21] xref: EC:6.1.1.21 xref: GO:0004821 xref: MetaCyc:HISTIDINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001180 name: isoleucine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)." [EC:6.1.1.5] subset: gosubset_prok synonym: "isoleucine translase activity" EXACT [EC:6.1.1.5] synonym: "isoleucine-transfer RNA ligase activity" EXACT [EC:6.1.1.5] synonym: "isoleucine-tRNA synthetase activity" EXACT [EC:6.1.1.5] synonym: "isoleucyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.5] synonym: "isoleucyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.5] synonym: "isoleucyl-tRNA synthetase activity" EXACT [] synonym: "L-isoleucine:tRNAIle ligase (AMP-forming)" EXACT [EC:6.1.1.5] xref: EC:6.1.1.5 xref: GO:0004822 xref: MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001181 name: leucine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)." [EC:6.1.1.4] subset: gosubset_prok synonym: "L-leucine:tRNALeu ligase (AMP-forming)" EXACT [EC:6.1.1.4] synonym: "leucine translase activity" EXACT [EC:6.1.1.4] synonym: "leucine-tRNA synthetase activity" EXACT [EC:6.1.1.4] synonym: "leucyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.4] synonym: "leucyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.4] synonym: "leucyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.4] synonym: "leucyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.4 xref: GO:0004823 xref: MetaCyc:LEUCINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001182 name: lysine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)." [EC:6.1.1.6] subset: gosubset_prok synonym: "L-lysine-transfer RNA ligase activity" EXACT [EC:6.1.1.6] synonym: "L-lysine:tRNALys ligase (AMP-forming)" EXACT [EC:6.1.1.6] synonym: "lysine translase activity" EXACT [EC:6.1.1.6] synonym: "lysine-tRNA synthetase activity" EXACT [EC:6.1.1.6] synonym: "lysyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.6] synonym: "lysyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.6] synonym: "lysyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.6 xref: GO:0004824 xref: MetaCyc:LYSINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001183 name: methionine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)." [EC:6.1.1.10] subset: gosubset_prok synonym: "L-methionine:tRNAMet ligase (AMP-forming)" EXACT [EC:6.1.1.10] synonym: "methionine translase activity" EXACT [EC:6.1.1.10] synonym: "methionyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.10] synonym: "methionyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.10] synonym: "methionyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.10] synonym: "methionyl-tRNA synthetase activity" EXACT [] synonym: "MetRS activity" EXACT [EC:6.1.1.10] xref: EC:6.1.1.10 xref: GO:0004825 xref: MetaCyc:METHIONINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001184 name: phenylalanine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)." [EC:6.1.1.20] subset: gosubset_prok synonym: "L-phenylalanine:tRNAPhe ligase (AMP-forming) activity" EXACT [EC:6.1.1.20] synonym: "L-phenylalanyl-tRNA synthetase activity" EXACT [EC:6.1.1.20] synonym: "phenylalanine translase activity" EXACT [EC:6.1.1.20] synonym: "phenylalanine-tRNA synthetase activity" EXACT [EC:6.1.1.20] synonym: "phenylalanyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.20] synonym: "phenylalanyl-transfer RNA ligase activity" EXACT [EC:6.1.1.20] synonym: "phenylalanyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.20] synonym: "phenylalanyl-tRNA ligase activity" EXACT [EC:6.1.1.20] synonym: "phenylalanyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.20 xref: GO:0004826 xref: MetaCyc:PHENYLALANINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001185 name: proline-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)." [EC:6.1.1.15] subset: gosubset_prok synonym: "L-proline:tRNAPro ligase (AMP-forming)" EXACT [EC:6.1.1.15] synonym: "proline translase activity" EXACT [EC:6.1.1.15] synonym: "prolinyl-tRNA ligase activity" EXACT [EC:6.1.1.15] synonym: "prolyl-s-RNA synthetase activity" EXACT [EC:6.1.1.15] synonym: "prolyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.15] synonym: "prolyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.15] synonym: "prolyl-transferRNA synthetase activity" EXACT [EC:6.1.1.15] synonym: "prolyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.15 xref: GO:0004827 xref: MetaCyc:PROLINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001186 name: serine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser)." [EC:6.1.1.11] subset: gosubset_prok synonym: "L-serine:tRNASer ligase (AMP-forming)" EXACT [EC:6.1.1.11] synonym: "serine translase activity" EXACT [EC:6.1.1.11] synonym: "SerRS activity" EXACT [EC:6.1.1.11] synonym: "seryl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.11] synonym: "seryl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.11] synonym: "seryl-transfer RNA synthetase activity" EXACT [EC:6.1.1.11] synonym: "seryl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.11 xref: GO:0004828 xref: MetaCyc:SERINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001187 name: threonine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr)." [EC:6.1.1.3] subset: gosubset_prok synonym: "L-threonine:tRNAThr ligase (AMP-forming)" EXACT [EC:6.1.1.3] synonym: "threonine translase activity" EXACT [EC:6.1.1.3] synonym: "threonine-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.3] synonym: "threonyl ribonucleic synthetase activity" EXACT [EC:6.1.1.3] synonym: "threonyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.3] synonym: "threonyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.3] synonym: "threonyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.3] synonym: "threonyl-tRNA synthetase activity" EXACT [] synonym: "TRS" RELATED [EC:6.1.1.3] xref: EC:6.1.1.3 xref: GO:0004829 xref: MetaCyc:THREONINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001188 name: tryptophan-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp)." [EC:6.1.1.2] subset: gosubset_prok synonym: "L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity" EXACT [EC:6.1.1.2] synonym: "L-tryptophan-tRNATrp ligase (AMP-forming)" EXACT [EC:6.1.1.2] synonym: "L-tryptophan:tRNATrp ligase (AMP-forming)" EXACT [EC:6.1.1.2] synonym: "TrpRS activity" EXACT [EC:6.1.1.2] synonym: "tryptophan translase activity" EXACT [EC:6.1.1.2] synonym: "tryptophanyl ribonucleic synthetase activity" EXACT [EC:6.1.1.2] synonym: "tryptophanyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.2] synonym: "tryptophanyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.2] synonym: "tryptophanyl-transfer ribonucleic synthetase activity" EXACT [EC:6.1.1.2] synonym: "tryptophanyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.2] synonym: "tryptophanyl-tRNA synthase activity" EXACT [EC:6.1.1.2] synonym: "tryptophanyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.2 xref: GO:0004830 xref: MetaCyc:TRYPTOPHAN--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001189 name: tyrosine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr)." [EC:6.1.1.1] subset: gosubset_prok synonym: "L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity" EXACT [EC:6.1.1.1] synonym: "L-tyrosine-tRNATyr ligase (AMP-forming)" EXACT [EC:6.1.1.1] synonym: "L-tyrosine:tRNATyr ligase (AMP-forming)" EXACT [EC:6.1.1.1] synonym: "tyrosine translase activity" EXACT [EC:6.1.1.1] synonym: "tyrosine tRNA synthetase activity" EXACT [EC:6.1.1.1] synonym: "tyrosine-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.1] synonym: "tyrosine-transfer RNA ligase activity" EXACT [EC:6.1.1.1] synonym: "tyrosyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.1] synonym: "tyrosyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.1] synonym: "tyrosyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.1] synonym: "tyrosyl-tRNA ligase activity" EXACT [EC:6.1.1.1] synonym: "tyrosyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.1 xref: GO:0004831 xref: MetaCyc:TYROSINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001190 name: valine-tRNA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)." [EC:6.1.1.9] subset: gosubset_prok synonym: "L-valine:tRNAVal ligase (AMP-forming)" EXACT [EC:6.1.1.9] synonym: "valine transfer ribonucleate ligase activity" EXACT [EC:6.1.1.9] synonym: "valine translase activity" EXACT [EC:6.1.1.9] synonym: "valyl-transfer ribonucleate synthetase activity" EXACT [EC:6.1.1.9] synonym: "valyl-transfer ribonucleic acid synthetase activity" EXACT [EC:6.1.1.9] synonym: "valyl-transfer RNA synthetase activity" EXACT [EC:6.1.1.9] synonym: "valyl-tRNA synthetase activity" EXACT [] xref: EC:6.1.1.9 xref: GO:0004832 xref: MetaCyc:VALINE--TRNA-LIGASE-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0001191 name: tryptophan 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine." [EC:1.13.11.11] subset: gosubset_prok synonym: "indolamine 2,3-dioxygenase activity" BROAD [EC:1.13.11.11] synonym: "indoleamine-pyrrole 2,3-dioxygenase activity" EXACT [] synonym: "L-tryptophan 2,3-dioxygenase activity" EXACT [EC:1.13.11.11] synonym: "L-tryptophan pyrrolase activity" EXACT [EC:1.13.11.11] synonym: "L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.11] synonym: "TDO" RELATED [EC:1.13.11.11] synonym: "tryptamin 2,3-dioxygenase activity" EXACT [EC:1.13.11.11] synonym: "tryptamine 2,3-dioxygenase activity" EXACT [EC:1.13.11.11] synonym: "tryptophan oxygenase activity" BROAD [EC:1.13.11.11] synonym: "tryptophan peroxidase activity" BROAD [EC:1.13.11.11] synonym: "tryptophan pyrrolase activity" BROAD [EC:1.13.11.11] xref: EC:1.13.11.11 xref: GO:0004426 xref: GO:0004833 xref: MetaCyc:INDOLEAMINE-PYRROLE-2 xref: MetaCyc:TRYPTOPHAN-2 xref: Reactome:15133 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0001192 name: tryptophan synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine + 1-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O." [EC:4.2.1.20] subset: gosubset_prok synonym: "indoleglycerol phosphate aldolase activity" EXACT [EC:4.2.1.20] synonym: "L-serine hydro-lyase (adding indoleglycerol-phosphate)" EXACT [EC:4.2.1.20] synonym: "L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]" RELATED [EC:4.2.1.20] synonym: "L-tryptophan synthetase activity" EXACT [EC:4.2.1.20] synonym: "tryptophan desmolase activity" EXACT [EC:4.2.1.20] synonym: "tryptophan synthetase activity" EXACT [EC:4.2.1.20] xref: EC:4.2.1.20 xref: GO:0004834 xref: MetaCyc:TRYPSYN-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001193 name: tubulin-tyrosine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate." [EC:6.3.2.25] synonym: "alpha-tubulin:L-tyrosine ligase (ADP-forming)" EXACT [EC:6.3.2.25] synonym: "TTL activity" EXACT [EC:6.3.2.25] synonym: "tubulinyl-tyrosine ligase activity" EXACT [] xref: EC:6.3.2.25 xref: GO:0004835 xref: MetaCyc:6.3.2.25-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0001194 name: tyramine-beta hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of tyramine to form octopamine." [PMID:10745161] xref: GO:0004836 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0001195 name: tyrosine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-tyrosine = tyramine + CO2." [EC:4.1.1.25] synonym: "L-(-)-tyrosine apodecarboxylase activity" EXACT [EC:4.1.1.25] synonym: "L-tyrosine carboxy-lyase (tyramine-forming)" EXACT [EC:4.1.1.25] synonym: "L-tyrosine carboxy-lyase activity" EXACT [EC:4.1.1.25] synonym: "L-tyrosine decarboxylase activity" EXACT [EC:4.1.1.25] xref: EC:4.1.1.25 xref: GO:0004837 xref: MetaCyc:TYROSINE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0001196 name: tyrosine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate." [EC:2.6.1.5] subset: gosubset_prok synonym: "glutamic phenylpyruvic aminotransferase activity" EXACT [EC:2.6.1.5] synonym: "glutamic-hydroxyphenylpyruvic transaminase activity" EXACT [EC:2.6.1.5] synonym: "L-phenylalanine 2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.5] synonym: "L-tyrosine aminotransferase activity" EXACT [EC:2.6.1.5] synonym: "L-tyrosine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.5] synonym: "phenylalanine aminotransferase activity" EXACT [EC:2.6.1.5] synonym: "phenylalanine transaminase activity" EXACT [EC:2.6.1.5] synonym: "phenylalanine-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.5] synonym: "phenylpyruvate transaminase activity" EXACT [EC:2.6.1.5] synonym: "phenylpyruvic acid transaminase activity" EXACT [EC:2.6.1.5] synonym: "TyrAT activity" EXACT [EC:2.6.1.5] synonym: "tyrosine aminotransferase activity" EXACT [] synonym: "tyrosine-2-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.5] synonym: "tyrosine-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.5] synonym: "tyrosine-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.5] xref: EC:2.6.1.5 xref: GO:0004838 xref: MetaCyc:TYROSINE-AMINOTRANSFERASE-RXN xref: Reactome:15141 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0001197 name: ubiquitin activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the C-terminal carboxyl group of ubiquitin by the formation of a high-energy thiolester bond in an ATP-dependent manner." [http://www.bostonbiochem.com/E-301.html, PMID:10072378] synonym: "E1" EXACT [] xref: GO:0004839 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0001198 name: ubiquitin-protein ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine." [EC:6.3.2.19, PMID:9635407] subset: gosubset_prok synonym: "E2" NARROW [] synonym: "E3" NARROW [] synonym: "ubiquitin activity" RELATED [EC:6.3.2.19] synonym: "ubiquitin conjugating enzyme activity" EXACT [] synonym: "ubiquitin ligase activity" EXACT [] synonym: "ubiquitin protein ligase activity" EXACT [] synonym: "ubiquitin protein-ligase activity" EXACT [] synonym: "ubiquitin-activating enzyme" EXACT [] synonym: "ubiquitin-conjugating enzyme activity" EXACT [] synonym: "ubiquitin-ligase activity" EXACT [] synonym: "ubiquitin:protein-lysine N-ligase (AMP-forming) activity" EXACT [EC:6.3.2.19] xref: EC:6.3.2.19 xref: GO:0004840 xref: GO:0004841 xref: GO:0004842 xref: MetaCyc:UBIQUITIN--PROTEIN-LIGASE-RXN xref: Reactome:15168 xref: Reactome:15171 is_a: CCO:F0004170 ! small conjugating protein ligase activity [Term] id: CCO:F0001199 name: ubiquitin-specific protease activity namespace: molecular_function def: "Catalysis of the hydrolysis of various forms of polymeric ubiquitin sequences. Will remove ubiquitin from larger leaving groups." [ISBN:0120793709] comment: Note that this term encompasses hydrolysis of any type of bonds formed between ubiquitin and another molecule. subset: gosubset_prok synonym: "UBP" NARROW [] synonym: "UCH2" NARROW [] xref: GO:0004843 is_a: CCO:F0004166 ! small conjugating protein-specific protease activity [Term] id: CCO:F0001200 name: uracil DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine." [GOC:elh, PMID:9224623] subset: gosubset_prok synonym: "uracil-DNA glycosylase activity" EXACT [] xref: EC:3.2.2.- xref: GO:0004844 xref: Reactome:15174 is_a: CCO:F0004051 ! DNA N-glycosylase activity [Term] id: CCO:F0001201 name: uracil phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.4.2.9] subset: gosubset_prok synonym: "UMP diphosphorylase activity" EXACT [EC:2.4.2.9] synonym: "UMP pyrophosphorylase activity" EXACT [EC:2.4.2.9] synonym: "UMP:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.9] synonym: "UMP:pyrophosphate phosphoribosyltransferase activity" EXACT [EC:2.4.2.9] synonym: "UPRTase activity" EXACT [EC:2.4.2.9] synonym: "uridine 5'-phosphate pyrophosphorylase activity" EXACT [EC:2.4.2.9] synonym: "uridine monophosphate pyrophosphorylase activity" EXACT [EC:2.4.2.9] synonym: "uridylate pyrophosphorylase activity" EXACT [EC:2.4.2.9] synonym: "uridylic pyrophosphorylase activity" EXACT [EC:2.4.2.9] xref: EC:2.4.2.9 xref: GO:0004845 xref: MetaCyc:URACIL-PRIBOSYLTRANS-RXN xref: Reactome:15175 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0001202 name: urate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + H2O2." [EC:1.7.3.3] subset: gosubset_prok synonym: "urate:oxygen oxidoreductase activity" EXACT [EC:1.7.3.3] synonym: "uric acid oxidase activity" EXACT [EC:1.7.3.3] synonym: "uricase activity" EXACT [EC:1.7.3.3] synonym: "uricase II activity" NARROW [EC:1.7.3.3] xref: EC:1.7.3.3 xref: GO:0004846 xref: MetaCyc:URATE-OXIDASE-RXN xref: UM-BBD_enzymeID:e0832 is_a: CCO:F0003258 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor [Term] id: CCO:F0001203 name: urea carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + urea + CO2 = ADP + phosphate + urea-1-carboxylate." [EC:6.3.4.6] subset: gosubset_prok synonym: "ATP--urea amidolyase activity" EXACT [EC:6.3.4.6] synonym: "UALase activity" EXACT [EC:6.3.4.6] synonym: "UCA activity" EXACT [EC:6.3.4.6] synonym: "urea amidolyase activity" EXACT [EC:6.3.4.6] synonym: "urea carboxylase (hydrolysing)" EXACT [EC:6.3.4.6] synonym: "urea carboxylase (hydrolyzing) activity" EXACT [EC:6.3.4.6] synonym: "urea:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.3.4.6] synonym: "urease (ATP-hydrolysing)" EXACT [EC:6.3.4.6] synonym: "urease (ATP-hydrolyzing) activity" EXACT [EC:6.3.4.6] xref: EC:6.3.4.6 xref: GO:0004847 xref: MetaCyc:UREA-CARBOXYLASE-RXN is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0001204 name: ureidoglycolate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2." [EC:3.5.3.19] subset: gosubset_prok synonym: "(S)-ureidoglycolate amidohydrolase (decarboxylating)" EXACT [EC:3.5.3.19] xref: EC:3.5.3.19 xref: GO:0004848 xref: MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0001205 name: uridine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + uridine = ADP + UMP." [EC:2.7.1.48] subset: gosubset_prok synonym: "ATP:uridine 5'-phosphotransferase activity" EXACT [EC:2.7.1.48] synonym: "pyrimidine ribonucleoside kinase activity" EXACT [EC:2.7.1.48] synonym: "uridine kinase (phosphorylating)" EXACT [EC:2.7.1.48] synonym: "uridine kinase reaction" EXACT [] synonym: "uridine monophosphokinase activity" EXACT [EC:2.7.1.48] synonym: "uridine phosphokinase activity" EXACT [EC:2.7.1.48] synonym: "uridine-cytidine kinase activity" EXACT [EC:2.7.1.48] xref: EC:2.7.1.48 xref: GO:0004849 xref: MetaCyc:URIDINEKIN-RXN is_a: CCO:F0004129 ! nucleoside kinase activity [Term] id: CCO:F0001206 name: uridine phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate." [EC:2.4.2.3] subset: gosubset_prok synonym: "pyrimidine phosphorylase activity" BROAD [EC:2.4.2.3] synonym: "UPase activity" EXACT [EC:2.4.2.3] synonym: "UPH" RELATED [EC:2.4.2.3] synonym: "UrdPase activity" EXACT [EC:2.4.2.3] synonym: "uridine:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.3] xref: EC:2.4.2.3 xref: GO:0004850 xref: MetaCyc:URPHOS-RXN xref: Reactome:15196 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0001207 name: uroporphyrin-III C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2." [EC:2.1.1.107] subset: gosubset_prok synonym: "adenosylmethionine-uroporphyrinogen III methyltransferase activity" EXACT [EC:2.1.1.107] synonym: "CobA" RELATED [EC:2.1.1.107] synonym: "CysG" RELATED [EC:2.1.1.107] synonym: "S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase activity" EXACT [EC:2.1.1.107] synonym: "S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase activity" EXACT [EC:2.1.1.107] synonym: "S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase activity" EXACT [EC:2.1.1.107] synonym: "SirA" RELATED [EC:2.1.1.107] synonym: "SUMT activity" EXACT [EC:2.1.1.107] synonym: "urogen III methylase activity" EXACT [EC:2.1.1.107] synonym: "uroporphyrinogen III methylase activity" EXACT [EC:2.1.1.107] synonym: "uroporphyrinogen methyltransferase activity" EXACT [EC:2.1.1.107] synonym: "uroporphyrinogen-III C-methyltransferase activity" EXACT [EC:2.1.1.107] synonym: "uroporphyrinogen-III methylase activity" EXACT [EC:2.1.1.107] synonym: "uroporphyrinogen-III methyltransferase activity" EXACT [EC:2.1.1.107] xref: EC:2.1.1.107 xref: GO:0004851 xref: MetaCyc:UROPORIIIMETHYLTRANSA-RXN is_a: CCO:F0001756 ! C-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001208 name: uroporphyrinogen-III synthase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxymethylbilane = uroporphyrinogen-III + H2O." [EC:4.2.1.75] subset: gosubset_prok synonym: "hydroxymethylbilane hydro-lyase (cyclizing) activity" EXACT [EC:4.2.1.75] synonym: "hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)" EXACT [EC:4.2.1.75] synonym: "porphobilinogenase activity" EXACT [EC:4.2.1.75] synonym: "URO-synthase activity" EXACT [EC:4.2.1.75] synonym: "uroporphyrinogen III cosynthase activity" EXACT [EC:4.2.1.75] synonym: "uroporphyrinogen isomerase activity" EXACT [EC:4.2.1.75] synonym: "uroporphyrinogen-III cosynthase activity" EXACT [EC:4.2.1.75] synonym: "uroporphyrinogen-III cosynthetase activity" EXACT [EC:4.2.1.75] xref: EC:4.2.1.75 xref: GO:0004852 xref: MetaCyc:UROGENIIISYN-RXN xref: Reactome:15200 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001209 name: uroporphyrinogen decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2." [EC:4.1.1.37] subset: gosubset_prok synonym: "porphyrinogen carboxy-lyase activity" EXACT [EC:4.1.1.37] synonym: "porphyrinogen decarboxylase activity" EXACT [EC:4.1.1.37] synonym: "uroporphyrinogen III decarboxylase activity" EXACT [EC:4.1.1.37] synonym: "uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming)" EXACT [EC:4.1.1.37] synonym: "uroporphyrinogen-III carboxy-lyase activity" EXACT [EC:4.1.1.37] xref: EC:4.1.1.37 xref: GO:0004853 xref: MetaCyc:UROGENDECARBOX-RXN xref: Reactome:15202 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0001210 name: xanthine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+." [EC:1.17.1.4] subset: gosubset_prok synonym: "NAD-xanthine dehydrogenase activity" EXACT [EC:1.17.1.4] synonym: "xanthine oxidoreductase activity" BROAD [EC:1.17.1.4] synonym: "xanthine-NAD oxidoreductase activity" EXACT [EC:1.17.1.4] synonym: "xanthine/NAD(+) oxidoreductase activity" EXACT [EC:1.17.1.4] synonym: "xanthine/NAD+ oxidoreductase activity" EXACT [EC:1.17.1.4] synonym: "xanthine:NAD+ oxidoreductase activity" EXACT [EC:1.17.1.4] xref: EC:1.17.1.4 xref: GO:0004854 xref: MetaCyc:XANTHINE-DEHYDROGENASE-RXN is_a: CCO:F0003308 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [Term] id: CCO:F0001211 name: xanthine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: xanthine + H2O + O2 = urate + H2O2." [EC:1.17.3.2] subset: gosubset_prok synonym: "hypoxanthine oxidase activity" EXACT [EC:1.17.3.2] synonym: "hypoxanthine-xanthine oxidase activity" EXACT [EC:1.17.3.2] synonym: "hypoxanthine:oxygen oxidoreductase activity" EXACT [EC:1.17.3.2] synonym: "schardinger enzyme" RELATED [EC:1.17.3.2] synonym: "Schardinger enzyme activity" EXACT [EC:1.17.3.2] synonym: "xanthine oxidoreductase activity" BROAD [EC:1.17.3.2] synonym: "xanthine:O(2) oxidoreductase activity" EXACT [EC:1.17.3.2] synonym: "xanthine:O2 oxidoreductase activity" EXACT [EC:1.17.3.2] synonym: "xanthine:oxygen oxidoreductase activity" EXACT [EC:1.17.3.2] synonym: "xanthine:xanthine oxidase activity" EXACT [EC:1.17.3.2] xref: EC:1.17.3.2 xref: GO:0004855 xref: MetaCyc:XANTHINE-OXIDASE-RXN xref: Reactome:15204 xref: UM-BBD_enzymeID:e0781 is_a: CCO:F0003309 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor [Term] id: CCO:F0001212 name: xylulokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate." [EC:2.7.1.17] subset: gosubset_prok synonym: "ATP:D-xylulose 5-phosphotransferase activity" EXACT [EC:2.7.1.17] synonym: "D-xylulokinase activity" EXACT [EC:2.7.1.17] synonym: "xylulokinase (phosphorylating)" EXACT [EC:2.7.1.17] synonym: "xylulose kinase activity" EXACT [EC:2.7.1.17] xref: EC:2.7.1.17 xref: GO:0004856 xref: MetaCyc:XYLULOKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0001213 name: enzyme inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of an enzyme." [GOC:ai] subset: gosubset_prok xref: GO:0004857 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0001214 name: dUTP pyrophosphatase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of dUTP pyrophosphatase." [GOC:mah] xref: GO:0004858 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0001215 name: phospholipase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid." [GOC:ai, GOC:rl] xref: GO:0004859 is_a: CCO:F0008232 ! lipase inhibitor activity [Term] id: CCO:F0001216 name: protein kinase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein." [GOC:ai] subset: gosubset_prok xref: GO:0004860 is_a: CCO:F0004133 ! kinase inhibitor activity is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0001217 name: cyclin-dependent protein kinase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a cyclin-dependent protein kinase." [GOC:mah] synonym: "CDK inhibitor" RELATED [] synonym: "cyclin dependent kinase inhibitor" RELATED [] synonym: "cyclin dependent protein kinase inhibitor activity" EXACT [] synonym: "cyclin-dependent kinase inhibitor" RELATED [] xref: GO:0004861 xref: Reactome:15226 is_a: CCO:F0003204 ! cyclin-dependent protein kinase regulator activity is_a: CCO:F0004378 ! protein serine/threonine kinase inhibitor activity [Term] id: CCO:F0001218 name: cAMP-dependent protein kinase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a cAMP-dependent protein kinase." [GOC:mah] xref: GO:0004862 is_a: CCO:F0004378 ! protein serine/threonine kinase inhibitor activity [Term] id: CCO:F0001219 name: diacylglycerol-activated phospholipid-dependent protein kinase C inhibitor activity namespace: molecular_function synonym: "diacylglycerol-activated phospholipid-dependent PKC inhibitor activity" EXACT [] xref: GO:0004863 is_a: CCO:F0001893 ! protein kinase C inhibitor activity [Term] id: CCO:F0001220 name: protein phosphatase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from proteins." [GOC:ai] xref: GO:0004864 is_a: CCO:F0004135 ! phosphatase inhibitor activity [Term] id: CCO:F0001221 name: type 1 serine/threonine specific protein phosphatase inhibitor activity namespace: molecular_function xref: GO:0004865 is_a: CCO:F0001220 ! protein phosphatase inhibitor activity [Term] id: CCO:F0001222 name: endopeptidase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide linkages in polypeptides." [GOC:jl] subset: gosubset_prok synonym: "alpha-2 macroglobulin" RELATED [] synonym: "endoproteinase inhibitor" EXACT [] synonym: "proteinase inhibitor" BROAD [] xref: GO:0004866 is_a: CCO:F0004441 ! protease inhibitor activity [Term] id: CCO:F0001223 name: serine-type endopeptidase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; a serine residue (and a histidine residue) are at the active center of the enzyme." [GOC:ai] subset: gosubset_prok synonym: "serine protease inhibitor activity" EXACT [] synonym: "serine proteinase inhibitor activity" EXACT [] synonym: "serpin activity" NARROW [] xref: GO:0004867 xref: Reactome:15233 is_a: CCO:F0001222 ! endopeptidase inhibitor activity [Term] id: CCO:F0001224 name: cysteine protease inhibitor activity namespace: molecular_function subset: gosubset_prok synonym: "thiol protease inhibitor" EXACT [] xref: GO:0004869 xref: GO:0004870 is_a: CCO:F0001222 ! endopeptidase inhibitor activity [Term] id: CCO:F0001225 name: signal transducer activity namespace: molecular_function def: "Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0004871 is_a: CCO:F0008240 ! molecular transducer activity [Term] id: CCO:F0001226 name: receptor activity namespace: molecular_function def: "Combining with an extracellular or intracellular messenger to initiate a change in cell activity." [GOC:ceb, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_goa subset: goslim_plant subset: gosubset_prok synonym: "receptor guanylate cyclase activity" NARROW [] xref: GO:0004872 is_a: CCO:F0001225 ! signal transducer activity [Term] id: CCO:F0001227 name: asialoglycoprotein receptor activity namespace: molecular_function def: "The mediation of the endocytosis of plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate moieties has been removed; recognizes the terminal galactose and N-acetylgalactosamine units; the complex of receptor and ligand is internalized and transported to a sorting organelle where disassociation occurs, the receptor being recycled to the cell membrane." [UniProtKB:P24721] xref: GO:0004873 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001228 name: aryl hydrocarbon receptor activity namespace: molecular_function def: "Combining with an aryl hydrocarbon to initiate a change in cell activity." [GOC:ai] xref: GO:0004874 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0001229 name: complement receptor activity namespace: molecular_function def: "Combining with any component or product of the complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways. xref: GO:0004875 is_a: CCO:F0000222 ! complement binding is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001230 name: complement component C3a receptor activity namespace: molecular_function def: "Combining with the C3a product of the complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0004876 is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0001231 name: complement component C3b receptor activity namespace: molecular_function def: "Combining with the C3b product of the complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0004877 is_a: CCO:F0000221 ! opsonin receptor activity is_a: CCO:F0000224 ! complement component C3a binding is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0001232 name: complement component C5a receptor activity namespace: molecular_function def: "Combining with the C5a product of the complement cascade to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0004878 is_a: CCO:F0000221 ! opsonin receptor activity is_a: CCO:F0000230 ! complement component C5a binding is_a: CCO:F0001229 ! complement receptor activity [Term] id: CCO:F0001233 name: ligand-dependent nuclear receptor activity namespace: molecular_function def: "A ligand-dependent receptor found in the nucleus of the cell." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. synonym: "nuclear hormone receptor" NARROW [] xref: GO:0004879 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0001234 name: juvenile hormone receptor activity namespace: molecular_function def: "Combining with juvenile hormone to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0004880 is_a: CCO:F0001233 ! ligand-dependent nuclear receptor activity [Term] id: CCO:F0001235 name: androgen receptor activity namespace: molecular_function def: "Combining with an androgen to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0004882 is_a: CCO:F0000295 ! steroid hormone receptor activity [Term] id: CCO:F0001236 name: glucocorticoid receptor activity namespace: molecular_function def: "Combining with a glucocorticoid to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0004883 is_a: CCO:F0000295 ! steroid hormone receptor activity [Term] id: CCO:F0001237 name: ecdysteroid hormone receptor activity namespace: molecular_function def: "Combining with ecdysteroid hormone to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0004884 is_a: CCO:F0000295 ! steroid hormone receptor activity [Term] id: CCO:F0001238 name: retinoid-X receptor activity namespace: molecular_function synonym: "RXR" EXACT [] xref: GO:0004886 is_a: CCO:F0000296 ! retinoic acid receptor activity [Term] id: CCO:F0001239 name: thyroid hormone receptor activity namespace: molecular_function def: "Combining with thyroid hormone to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0004887 is_a: CCO:F0001233 ! ligand-dependent nuclear receptor activity [Term] id: CCO:F0001240 name: transmembrane receptor activity namespace: molecular_function def: "Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle." [GOC:go_curators, http://en.wikipedia.org/] subset: gosubset_prok xref: GO:0004888 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0001241 name: nicotinic acetylcholine-activated cation-selective channel activity namespace: molecular_function xref: GO:0004889 xref: GO:0016904 is_a: CCO:F0001506 ! excitatory extracellular ligand-gated ion channel activity is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0001242 name: GABA-A receptor activity namespace: molecular_function def: "Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels." [PMID:8974333] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'chloride channel activity ; GO:0005254' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'. xref: GO:0004890 is_a: CCO:F0003467 ! GABA receptor activity [Term] id: CCO:F0001243 name: glycine-inhibited chloride channel activity namespace: molecular_function comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'receptor activity ; GO:0004872'. xref: GO:0004891 is_a: CCO:F0001509 ! inhibitory extracellular ligand-gated ion channel activity is_a: CCO:F0001522 ! chloride channel activity [Term] id: CCO:F0001244 name: hematopoietin/interferon-class (D200-domain) cytokine receptor activity namespace: molecular_function xref: GO:0004896 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001245 name: ciliary neurotrophic factor receptor activity namespace: molecular_function synonym: "gp130" NARROW [] xref: GO:0004897 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0001246 name: leukemia inhibitory factor receptor beta-protein activity namespace: molecular_function xref: GO:0004899 is_a: CCO:F0001245 ! ciliary neurotrophic factor receptor activity is_a: CCO:F0001376 ! hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity [Term] id: CCO:F0001247 name: erythropoietin receptor activity namespace: molecular_function def: "Combining with erythropoietin to initiate a change in cell activity." [GOC:ai] xref: GO:0004900 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0001248 name: granulocyte macrophage colony-stimulating factor receptor activity namespace: molecular_function def: "Combining with granulocyte macrophage colony-stimulating factor to initiate a change in cell activity." [GOC:mah] synonym: "CSF-2" RELATED [] synonym: "GM-CSF receptor activity" EXACT [] synonym: "GMC-SF receptor activity" EXACT [] xref: GO:0004901 xref: GO:0030525 is_a: CCO:F0001247 ! erythropoietin receptor activity [Term] id: CCO:F0001249 name: granulocyte colony-stimulating factor receptor activity namespace: molecular_function def: "Combining with granulocyte colony-stimulating factor to initiate a change in cell activity." [GOC:mah] xref: GO:0004902 xref: GO:0030524 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0001250 name: growth hormone receptor activity namespace: molecular_function def: "Combining with growth hormone to initiate a change in cell activity." [GOC:ai] xref: GO:0004903 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0001251 name: interferon receptor activity namespace: molecular_function def: "Combining with an interferon to initiate a change in cell activity." [GOC:ai] xref: GO:0004904 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity is_a: CCO:F0004227 ! interferon binding [Term] id: CCO:F0001253 name: interferon-gamma receptor activity namespace: molecular_function def: "Combining with interferon-gamma to initiate a change in cell activity. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:ai, ISBN:0126896631, PMID:15546383] synonym: "type II interferon receptor activity" EXACT [] xref: GO:0004906 is_a: CCO:F0001251 ! interferon receptor activity is_a: CCO:F0004229 ! interferon-gamma binding [Term] id: CCO:F0001254 name: interleukin receptor activity namespace: molecular_function def: "Combining with an interleukin to initiate a change in cell activity." [GOC:ai] synonym: "IL receptor" EXACT [] xref: GO:0004907 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0001255 name: interleukin-1 receptor activity namespace: molecular_function def: "Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response." [GOC:jl] synonym: "IL-1R" EXACT [] xref: GO:0004908 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004231 ! interleukin-1 binding [Term] id: CCO:F0001256 name: interleukin-1, Type I, activating receptor activity namespace: molecular_function synonym: "IL-1 type I, activating receptor" EXACT [] xref: GO:0004909 is_a: CCO:F0001255 ! interleukin-1 receptor activity is_a: CCO:F0004232 ! interleukin-1, Type I, activating binding [Term] id: CCO:F0001257 name: interleukin-1, Type II, blocking receptor activity namespace: molecular_function synonym: "IL-1 type II, blocking receptor" EXACT [] xref: GO:0004910 is_a: CCO:F0001255 ! interleukin-1 receptor activity is_a: CCO:F0004233 ! interleukin-1, Type II, blocking binding [Term] id: CCO:F0001258 name: interleukin-2 receptor activity namespace: molecular_function def: "Combining with interleukin-2 to initiate a change in cell activity." [GOC:jl] synonym: "IL-2R" EXACT [] xref: GO:0004911 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004240 ! interleukin-2 binding [Term] id: CCO:F0001259 name: interleukin-3 receptor activity namespace: molecular_function def: "Combining with interleukin-3 to initiate a change in cell activity." [GOC:jl] synonym: "IL-3R" EXACT [] xref: GO:0004912 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004242 ! interleukin-3 binding [Term] id: CCO:F0001260 name: interleukin-4 receptor activity namespace: molecular_function def: "Combining with interleukin-4 to initiate a change in cell activity." [GOC:jl] synonym: "IL-4R" EXACT [] xref: GO:0004913 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004243 ! interleukin-4 binding [Term] id: CCO:F0001261 name: interleukin-5 receptor activity namespace: molecular_function def: "Combining with interleukin-5 to initiate a change in cell activity." [GOC:jl] synonym: "IL-5R" EXACT [] xref: GO:0004914 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004244 ! interleukin-5 binding [Term] id: CCO:F0001262 name: interleukin-6 receptor activity namespace: molecular_function def: "Combining with interleukin-6 to initiate a change in cell activity." [GOC:jl] synonym: "gp130" NARROW [] synonym: "IL-6R" EXACT [] xref: GO:0004915 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004245 ! interleukin-6 binding [Term] id: CCO:F0001263 name: interleukin-7 receptor activity namespace: molecular_function def: "Combining with interleukin-7 to initiate a change in cell activity." [GOC:jl] synonym: "IL-7R" EXACT [] xref: GO:0004917 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004246 ! interleukin-7 binding [Term] id: CCO:F0001264 name: interleukin-8 receptor activity namespace: molecular_function def: "Combining with interleukin-8 to initiate a change in cell activity." [GOC:jl] synonym: "IL-8R" EXACT [] xref: GO:0004918 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0003175 ! C-X-C chemokine receptor activity is_a: CCO:F0004225 ! interleukin-8 binding [Term] id: CCO:F0001265 name: interleukin-9 receptor activity namespace: molecular_function def: "Combining with interleukin-9 to initiate a change in cell activity." [GOC:jl] synonym: "IL-9R" EXACT [] xref: GO:0004919 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004247 ! interleukin-9 binding [Term] id: CCO:F0001266 name: interleukin-10 receptor activity namespace: molecular_function def: "Combining with interleukin-10 to initiate a change in cell activity." [GOC:jl] synonym: "IL-10R" EXACT [] xref: GO:0004920 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004234 ! interleukin-10 binding [Term] id: CCO:F0001267 name: interleukin-11 receptor activity namespace: molecular_function def: "Combining with interleukin-11 to initiate a change in cell activity." [GOC:jl] synonym: "gp130" NARROW [] synonym: "IL-11R" EXACT [] xref: GO:0004921 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004235 ! interleukin-11 binding [Term] id: CCO:F0001268 name: leukemia inhibitory factor receptor activity namespace: molecular_function def: "Combining with leukemia inhibitory factor to initiate a change in cell activity." [GOC:mah] xref: GO:0004923 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0001269 name: oncostatin-M receptor activity namespace: molecular_function def: "Combining with oncostatin-M to initiate a change in cell activity." [GOC:mah] xref: GO:0004924 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0001270 name: prolactin receptor activity namespace: molecular_function def: "Combining with prolactin to initiate a change in cell activity." [GOC:mah] xref: GO:0004925 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0001271 name: non-G-protein coupled 7TM receptor activity namespace: molecular_function subset: gosubset_prok synonym: "non G protein coupled 7TM receptor activity" EXACT [] synonym: "non-G-protein-coupled 7TM receptor activity" EXACT [] xref: GO:0004926 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001272 name: G-protein coupled receptor activity namespace: molecular_function def: "A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers." [GOC:dph, GOC:tb, http://www.iuphar-db.org] subset: gosubset_prok synonym: "G protein coupled receptor activity" EXACT [] synonym: "G protein linked receptor activity" EXACT [] synonym: "G-protein coupled receptor activity, unknown ligand" EXACT [] synonym: "G-protein linked receptor activity" EXACT [] synonym: "G-protein-coupled receptor activity" EXACT [] synonym: "GPCR activity" EXACT [] synonym: "orphan G protein coupled receptor activity" EXACT [] synonym: "orphan G-protein coupled receptor activity" EXACT [] synonym: "orphan GPCR activity" EXACT [] xref: GO:0004930 xref: GO:0016526 xref: Reactome:35 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001273 name: ATP-gated cation channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts." [GOC:mah, PMID:9755289] comment: Note that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'. synonym: "P2X activity" RELATED [] synonym: "purinoceptor" BROAD [] synonym: "purinoreceptor" BROAD [] xref: GO:0004931 is_a: CCO:F0001506 ! excitatory extracellular ligand-gated ion channel activity is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0001274 name: mating-type factor pheromone receptor activity namespace: molecular_function def: "Combining with a mating-type factor pheromone to initiate a change in cell activity." [GOC:dph] subset: gosubset_prok xref: GO:0004932 is_a: CCO:F0003184 ! pheromone receptor activity [Term] id: CCO:F0001275 name: mating-type a-factor pheromone receptor activity namespace: molecular_function def: "Combining with the mating-type a-factor pheromone to initiate a change in cell activity." [GOC:mah] synonym: "class D G protein coupled receptor activity" BROAD [] synonym: "class D G-protein coupled receptor activity" BROAD [] synonym: "class D G-protein-coupled receptor activity" BROAD [] synonym: "class D GPCR activity" BROAD [] xref: GO:0004933 is_a: CCO:F0001274 ! mating-type factor pheromone receptor activity [Term] id: CCO:F0001276 name: mating-type alpha-factor pheromone receptor activity namespace: molecular_function def: "Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity." [GOC:mah] synonym: "class D G protein coupled receptor activity" BROAD [] synonym: "class D G-protein coupled receptor activity" BROAD [] synonym: "class D G-protein-coupled receptor activity" BROAD [] synonym: "class D GPCR activity" BROAD [] xref: GO:0004934 is_a: CCO:F0001274 ! mating-type factor pheromone receptor activity [Term] id: CCO:F0001277 name: adrenoceptor activity namespace: molecular_function synonym: "adrenergic receptor" EXACT [] xref: GO:0004935 is_a: CCO:F0001782 ! amine receptor activity [Term] id: CCO:F0001278 name: alpha-adrenergic receptor activity namespace: molecular_function synonym: "alpha adrenoceptor" EXACT [] xref: GO:0004936 is_a: CCO:F0001277 ! adrenoceptor activity [Term] id: CCO:F0001279 name: alpha1-adrenergic receptor activity namespace: molecular_function synonym: "alpha1 adrenoceptor" EXACT [] xref: GO:0004937 is_a: CCO:F0001278 ! alpha-adrenergic receptor activity [Term] id: CCO:F0001280 name: alpha2-adrenergic receptor activity namespace: molecular_function synonym: "alpha2 adrenoceptor" EXACT [] xref: GO:0004938 is_a: CCO:F0001278 ! alpha-adrenergic receptor activity [Term] id: CCO:F0001281 name: beta-adrenergic receptor activity namespace: molecular_function synonym: "beta adrenoceptor" EXACT [] xref: GO:0004939 is_a: CCO:F0001277 ! adrenoceptor activity [Term] id: CCO:F0001282 name: beta1-adrenergic receptor activity namespace: molecular_function synonym: "beta1 adrenoceptor" EXACT [] xref: GO:0004940 is_a: CCO:F0001281 ! beta-adrenergic receptor activity [Term] id: CCO:F0001283 name: beta2-adrenergic receptor activity namespace: molecular_function synonym: "beta2 adrenoceptor" EXACT [] xref: GO:0004941 is_a: CCO:F0001281 ! beta-adrenergic receptor activity [Term] id: CCO:F0001284 name: anaphylatoxin receptor activity namespace: molecular_function def: "Combining with anaphylatoxin to initiate a change in cell activity." [GOC:ai] xref: GO:0004942 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0001285 name: C3a anaphylatoxin receptor activity namespace: molecular_function def: "Combining with anaphylatoxin C3a to initiate a change in cell activity." [GOC:mah] xref: GO:0004943 is_a: CCO:F0001284 ! anaphylatoxin receptor activity [Term] id: CCO:F0001286 name: C5a anaphylatoxin receptor activity namespace: molecular_function def: "Combining with anaphylatoxin C5a to initiate a change in cell activity." [GOC:mah] xref: GO:0004944 is_a: CCO:F0001284 ! anaphylatoxin receptor activity [Term] id: CCO:F0001287 name: angiotensin type II receptor activity namespace: molecular_function xref: GO:0004945 is_a: CCO:F0000151 ! angiotensin receptor activity [Term] id: CCO:F0001288 name: bombesin receptor activity namespace: molecular_function def: "Combining with bombesin to initiate a change in cell activity." [GOC:ai] xref: GO:0004946 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0001289 name: bradykinin receptor activity namespace: molecular_function def: "Combining with bradykinin to initiate a change in cell activity." [GOC:ai] xref: GO:0004947 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0001290 name: calcitonin receptor activity namespace: molecular_function def: "Combining with calcitonin to initiate a change in cell activity." [GOC:mah] xref: GO:0004948 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0001291 name: cannabinoid receptor activity namespace: molecular_function def: "Combining with cannabinoids to initiate a change in cell activity." [GOC:dph, IUPHAR_GPCR:1279] synonym: "cannaboid receptor" EXACT [] xref: GO:0004949 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001292 name: chemokine receptor activity namespace: molecular_function def: "Combining with chemokines, small chemoattractant molecules normally used to stimulate leukocytes, to initiate a change in cell activity." [IUPHAR_GPCR:1280, PMID:8662823] xref: GO:0004950 is_a: CCO:F0000187 ! G-protein chemoattractant receptor activity is_a: CCO:F0004222 ! chemokine binding [Term] id: CCO:F0001293 name: cholecystokinin receptor activity namespace: molecular_function def: "Combining with cholecystokinin, a 33-amino acid peptide secreted by the upper intestinal mucosa and also found in the central nervous system, to initiate a change in cell activity." [GOC:ai, http://cancerweb.ncl.ac.uk/] xref: GO:0004951 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0001294 name: dopamine receptor activity namespace: molecular_function def: "Combining with the neurotransmitter dopamine to initiate a change in cell activity." [IUPHAR_GPCR:1282] xref: GO:0004952 is_a: CCO:F0001782 ! amine receptor activity is_a: CCO:F0004488 ! neurotransmitter receptor activity is_a: CCO:F0005573 ! dopamine binding [Term] id: CCO:F0001295 name: icosanoid receptor activity namespace: molecular_function def: "Combining with an icosanoid to initiate a change in cell activity." [GOC:dph] synonym: "eicosanoid receptor activity" EXACT [] xref: GO:0004953 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001296 name: prostanoid receptor activity namespace: molecular_function def: "Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0004954 is_a: CCO:F0001295 ! icosanoid receptor activity [Term] id: CCO:F0001297 name: prostaglandin receptor activity namespace: molecular_function def: "Combining with a prostaglandin (PG) to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0004955 is_a: CCO:F0001296 ! prostanoid receptor activity [Term] id: CCO:F0001298 name: prostaglandin D receptor activity namespace: molecular_function def: "Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "PGD receptor activity" RELATED [] synonym: "PGD(2) receptor activity" EXACT [] xref: GO:0004956 is_a: CCO:F0001297 ! prostaglandin receptor activity [Term] id: CCO:F0001299 name: prostaglandin E receptor activity namespace: molecular_function def: "Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "PGE receptor activity" RELATED [] synonym: "PGE(2) receptor activity" EXACT [] xref: GO:0004957 is_a: CCO:F0001297 ! prostaglandin receptor activity [Term] id: CCO:F0001300 name: prostaglandin F receptor activity namespace: molecular_function def: "Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "PGF receptor activity" RELATED [] synonym: "PGF(2-alpha) receptor activity" EXACT [] xref: GO:0004958 is_a: CCO:F0001297 ! prostaglandin receptor activity [Term] id: CCO:F0001301 name: thromboxane receptor activity namespace: molecular_function def: "Combining with a thromboxane (TXA) to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "TXA receptor activity" EXACT [] xref: GO:0004960 is_a: CCO:F0001296 ! prostanoid receptor activity [Term] id: CCO:F0001302 name: thromboxane A2 receptor activity namespace: molecular_function def: "Combining with thromboxane A2 (TXA(2)) to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "TXA(2) receptor activity" EXACT [] xref: GO:0004961 is_a: CCO:F0001301 ! thromboxane receptor activity [Term] id: CCO:F0001303 name: endothelin receptor activity namespace: molecular_function def: "Combining with endothelin to initiate a change in cell activity." [GOC:dph, IUPHAR_GPCR:1283] xref: GO:0004962 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0001304 name: follicle-stimulating hormone receptor activity namespace: molecular_function def: "Combining with follicle-stimulating hormone to initiate a change in cell activity." [GOC:mah] synonym: "follicle stimulating hormone receptor activity" EXACT [] xref: GO:0004963 is_a: CCO:F0003181 ! protein-hormone receptor activity [Term] id: CCO:F0001305 name: lutropin-choriogonadotropic hormone receptor activity namespace: molecular_function def: "Combining with lutropin-choriogonadotropic hormone to initiate a change in cell activity." [GOC:mah] xref: GO:0004964 xref: GO:0004976 is_a: CCO:F0003181 ! protein-hormone receptor activity [Term] id: CCO:F0001306 name: GABA-B receptor activity namespace: molecular_function def: "Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-B receptors are G-protein coupled receptors." [GOC:ai, IUPHAR_RECEPTOR:1276] xref: GO:0004965 is_a: CCO:F0001696 ! metabotropic glutamate, GABA-B-like receptor activity is_a: CCO:F0003467 ! GABA receptor activity [Term] id: CCO:F0001307 name: galanin receptor activity namespace: molecular_function def: "Combining with galanin to initiate a change in cell activity." [GOC:ai] xref: GO:0004966 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0001308 name: glucagon receptor activity namespace: molecular_function def: "Combining with glucagon to initiate a change in cell activity." [GOC:mah] xref: GO:0004967 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0001309 name: gonadotropin-releasing hormone receptor activity namespace: molecular_function def: "Combining with gonadotropin-releasing hormone to initiate a change in cell activity." [GOC:mah] xref: GO:0004968 is_a: CCO:F0003181 ! protein-hormone receptor activity [Term] id: CCO:F0001310 name: histamine receptor activity namespace: molecular_function def: "Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] xref: GO:0004969 is_a: CCO:F0001782 ! amine receptor activity [Term] id: CCO:F0001311 name: ionotropic glutamate receptor activity namespace: molecular_function def: "Combining with glutamate to initiate a change in cell activity through the regulation of ion channels." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'. subset: gosubset_prok xref: GO:0004970 is_a: CCO:F0001695 ! glutamate receptor activity [Term] id: CCO:F0001312 name: alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity namespace: molecular_function comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'inotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'. xref: GO:0004971 is_a: CCO:F0001311 ! ionotropic glutamate receptor activity [Term] id: CCO:F0001313 name: N-methyl-D-aspartate selective glutamate receptor activity namespace: molecular_function comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'inotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'. synonym: "NMDA receptor" EXACT [] xref: GO:0004972 is_a: CCO:F0001311 ! ionotropic glutamate receptor activity [Term] id: CCO:F0001314 name: leukotriene receptor activity namespace: molecular_function def: "Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide moiety based on cysteine." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0004974 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001315 name: melanocortin receptor activity namespace: molecular_function def: "Combining with melanocortin to initiate a change in cell activity." [GOC:ai] xref: GO:0004977 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0001316 name: adrenocorticotropin receptor activity namespace: molecular_function def: "Combining with adrenocorticotropin to initiate a change in cell activity." [GOC:ai] synonym: "ACTH receptor activity" EXACT [] synonym: "adrenocorticotropic hormone receptor activity" EXACT [] xref: GO:0004978 is_a: CCO:F0001315 ! melanocortin receptor activity is_a: CCO:F0001769 ! neuropeptide receptor activity is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0001317 name: beta-endorphin receptor activity namespace: molecular_function def: "Combining with beta-endorphin to initiate a change in cell activity." [GOC:ai] xref: GO:0004979 is_a: CCO:F0001315 ! melanocortin receptor activity is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0001318 name: melanocyte stimulating hormone receptor activity namespace: molecular_function def: "Combining with melanocyte stimulating hormone to initiate a change in cell activity." [GOC:jl, UniProtKB:Q01726] synonym: "melanophore stimulating hormone receptor activity" EXACT [] synonym: "MSH receptor activity" BROAD [] synonym: "MSHR activity" BROAD [] xref: GO:0004980 is_a: CCO:F0001315 ! melanocortin receptor activity is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0001319 name: muscarinic acetylcholine receptor activity namespace: molecular_function xref: GO:0004981 is_a: CCO:F0001782 ! amine receptor activity is_a: CCO:F0002870 ! acetylcholine receptor activity [Term] id: CCO:F0001320 name: N-formyl peptide receptor activity namespace: molecular_function def: "Combining with an N-formyl peptide to initiate a change in cell activity." [GOC:ai] synonym: "Fmet-leu-phe receptor" EXACT [] xref: GO:0004982 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0001321 name: neuropeptide Y receptor activity namespace: molecular_function def: "Combining with neuropeptide Y to initiate a change in cell activity." [PMID:9315606] xref: GO:0004983 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0001322 name: olfactory receptor activity namespace: molecular_function def: "Combining with airborne compounds to initiate a change in cell activity. These receptors are used for the sense of smell." [GOC:dph] xref: GO:0004984 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001323 name: opioid receptor activity namespace: molecular_function def: "Combining with an opioid, any narcotic derived from or resembling opium, to initiate a change in cell activity." [GOC:ai, http://cancerweb.ncl.ac.uk/] xref: GO:0004985 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0001324 name: delta-opioid receptor activity namespace: molecular_function xref: GO:0004986 is_a: CCO:F0001323 ! opioid receptor activity [Term] id: CCO:F0001325 name: kappa-opioid receptor activity namespace: molecular_function xref: GO:0004987 is_a: CCO:F0001323 ! opioid receptor activity [Term] id: CCO:F0001326 name: mu-opioid receptor activity namespace: molecular_function xref: GO:0004988 is_a: CCO:F0001323 ! opioid receptor activity [Term] id: CCO:F0001327 name: octopamine receptor activity namespace: molecular_function def: "Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist." [GOC:ai, http://cancerweb.ncl.ac.uk/] xref: GO:0004989 is_a: CCO:F0001782 ! amine receptor activity [Term] id: CCO:F0001328 name: oxytocin receptor activity namespace: molecular_function def: "Combining with oxytocin to initiate a change in cell activity." [GOC:ai] xref: GO:0004990 is_a: CCO:F0000158 ! vasopressin-like receptor activity [Term] id: CCO:F0001329 name: parathyroid hormone receptor activity namespace: molecular_function def: "Combining with parathyroid hormone to initiate a change in cell activity." [GOC:mah] xref: GO:0004991 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0001330 name: platelet activating factor receptor activity namespace: molecular_function def: "Combining with platelet activating factor to initiate a change in cell activity." [GOC:mah] synonym: "PAF receptor activity" EXACT [] xref: GO:0004992 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001331 name: serotonin receptor activity namespace: molecular_function def: "Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity." [GOC:ai, http://cancerweb.ncl.ac.uk/] synonym: "5-HT receptor" EXACT [] synonym: "5-hydroxytryptamine receptor" EXACT [] xref: GO:0001585 xref: GO:0004993 is_a: CCO:F0001782 ! amine receptor activity [Term] id: CCO:F0001332 name: somatostatin receptor activity namespace: molecular_function def: "Combining with somatostatin to initiate a change in cell activity." [GOC:ai] xref: GO:0004994 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0001333 name: tachykinin receptor activity namespace: molecular_function def: "Combining with tachykinin to initiate a change in cell activity." [GOC:ai] xref: GO:0004995 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0001334 name: thyroid-stimulating hormone receptor activity namespace: molecular_function def: "Combining with thyroid-stimulating hormone to initiate a change in cell activity." [GOC:mah] synonym: "thyrotropin receptor" EXACT [] xref: GO:0004996 is_a: CCO:F0003181 ! protein-hormone receptor activity [Term] id: CCO:F0001335 name: thyrotropin-releasing hormone receptor activity namespace: molecular_function xref: GO:0004997 is_a: CCO:F0000166 ! thyrotropin releasing hormone and secretagogue-like receptors activity [Term] id: CCO:F0001336 name: transferrin receptor activity namespace: molecular_function def: "Combining with transferrin to initiate a change in cell activity." [GOC:mah] subset: gosubset_prok xref: GO:0004998 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001337 name: vasoactive intestinal polypeptide receptor activity namespace: molecular_function xref: GO:0004999 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0001338 name: vasopressin receptor activity namespace: molecular_function def: "Combining with vasopressin to initiate a change in cell activity." [GOC:ai] xref: GO:0005000 is_a: CCO:F0000158 ! vasopressin-like receptor activity [Term] id: CCO:F0001339 name: transmembrane receptor protein tyrosine phosphatase activity namespace: molecular_function xref: GO:0005001 is_a: CCO:F0001090 ! protein tyrosine phosphatase activity is_a: CCO:F0004121 ! transmembrane receptor protein phosphatase activity [Term] id: CCO:F0001340 name: ephrin receptor activity namespace: molecular_function def: "Combining with an ephrin to initiate a change in cell activity." [GOC:mah] synonym: "Eph receptor activity" EXACT [] xref: GO:0005003 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001341 name: GPI-linked ephrin receptor activity namespace: molecular_function synonym: "GPI-linked Eph receptor activity" EXACT [] xref: GO:0005004 is_a: CCO:F0001340 ! ephrin receptor activity [Term] id: CCO:F0001342 name: transmembrane-ephrin receptor activity namespace: molecular_function synonym: "transmembrane-Eph receptor activity" EXACT [] xref: GO:0005005 is_a: CCO:F0001340 ! ephrin receptor activity [Term] id: CCO:F0001343 name: epidermal growth factor receptor activity namespace: molecular_function def: "Combining with an epidermal growth factor to initiate a change in cell activity." [GOC:bf] subset: gosubset_prok synonym: "EGF receptor activity" EXACT [] synonym: "EGFR" EXACT [] synonym: "TGF-alpha receptor activity" EXACT [] synonym: "transforming growth factor-alpha receptor activity" EXACT [] xref: GO:0005006 xref: GO:0005023 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001344 name: fibroblast growth factor receptor activity namespace: molecular_function def: "Combining with fibroblast growth factor to initiate a change in cell activity." [GOC:mah] synonym: "FGF receptor activity" EXACT [] synonym: "FGFR" EXACT [] xref: GO:0005007 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001345 name: hepatocyte growth factor receptor activity namespace: molecular_function def: "Combining with hepatocye growth factor to initiate a change in cell activity." [GOC:mah] synonym: "HGF receptor activity" EXACT [] xref: GO:0005008 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001346 name: insulin receptor activity namespace: molecular_function def: "Combining with insulin to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005009 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001347 name: insulin-like growth factor receptor activity namespace: molecular_function synonym: "IGF receptor activity" EXACT [] xref: GO:0005010 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001348 name: macrophage colony stimulating factor receptor activity namespace: molecular_function def: "Combining with macrophage colony stimulating factor to initiate a change in cell activity." [GOC:mah] synonym: "CSF-1" NARROW [] synonym: "Fms" NARROW [] xref: GO:0005011 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001349 name: platelet-derived growth factor receptor activity namespace: molecular_function def: "Combining with platelet-derived growth factor to initiate a change in cell activity." [GOC:mah] synonym: "PDGF receptor activity" EXACT [] synonym: "PDGFR activity" EXACT [] xref: GO:0005017 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001350 name: platelet-derived growth factor alpha-receptor activity namespace: molecular_function synonym: "PDGF alpha-receptor activity" EXACT [] xref: GO:0005018 is_a: CCO:F0001349 ! platelet-derived growth factor receptor activity [Term] id: CCO:F0001351 name: platelet-derived growth factor beta-receptor activity namespace: molecular_function synonym: "PDGF beta-receptor activity" EXACT [] xref: GO:0005019 is_a: CCO:F0001349 ! platelet-derived growth factor receptor activity [Term] id: CCO:F0001352 name: stem cell factor receptor activity namespace: molecular_function def: "Combining with stem cell factor, a cytokine that stimulates mast cell growth and differentiation, to initiate a change in cell activity." [GOC:jl, PMID:10698217] xref: GO:0005020 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001353 name: vascular endothelial growth factor receptor activity namespace: molecular_function def: "Combining with vascular endothelial growth factor to initiate a change in cell activity." [GOC:mah] xref: GO:0005021 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001354 name: transforming growth factor beta receptor activity namespace: molecular_function def: "Combining with transforming growth factor beta to initiate a change in cell activity." [GOC:mah] synonym: "TGF-beta receptor activity" EXACT [] synonym: "TGFbeta receptor activity" EXACT [] synonym: "TGFbetaR" EXACT [] xref: GO:0005024 is_a: CCO:F0001046 ! transmembrane receptor protein serine/threonine kinase activity [Term] id: CCO:F0001355 name: transforming growth factor beta receptor activity, type I namespace: molecular_function def: "Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, catalyzes the phosphorylation of a type I TGF-beta receptor." [GOC:mah] synonym: "transforming growth factor beta ligand binding to type I receptor" RELATED [] synonym: "type I TGF-beta receptor activity" EXACT [] synonym: "type I TGFbeta receptor activity" EXACT [] synonym: "type I transforming growth factor beta receptor activity" EXACT [] xref: GO:0005025 is_a: CCO:F0001354 ! transforming growth factor beta receptor activity [Term] id: CCO:F0001356 name: transforming growth factor beta receptor activity, type II namespace: molecular_function def: "Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, catalyzes the phosphorylation of a type I activin receptor." [GOC:mah] synonym: "transforming growth factor beta ligand binding to type II receptor" RELATED [] synonym: "type II TGF-beta receptor activity" EXACT [] synonym: "type II TGFbeta receptor activity" EXACT [] synonym: "type II transforming growth factor beta receptor activity" EXACT [] xref: GO:0005026 xref: Reactome:11166 is_a: CCO:F0001354 ! transforming growth factor beta receptor activity [Term] id: CCO:F0001357 name: neurotrophin receptor activity namespace: molecular_function def: "Combining with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth, to initiate a change in cell activity." [GOC:jl, http://www.mercksource.com/] xref: GO:0005030 is_a: CCO:F0001226 ! receptor activity is_a: CCO:F0005795 ! neurotrophin binding [Term] id: CCO:F0001358 name: tumor necrosis factor receptor activity namespace: molecular_function def: "Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function." [GOC:jl, http://lookwayup.com/] synonym: "NGF/TNF (6 C-domain) receptor activity" NARROW [] synonym: "TNF receptor activity" EXACT [] synonym: "TNF receptor activity, type I" NARROW [] synonym: "TNF receptor activity, type II" NARROW [] synonym: "tumor necrosis factor receptor activity, type I" NARROW [] synonym: "tumor necrosis factor receptor activity, type II" NARROW [] xref: GO:0005031 xref: GO:0005032 xref: GO:0005033 is_a: CCO:F0001360 ! death receptor activity is_a: CCO:F0005794 ! tumor necrosis factor binding [Term] id: CCO:F0001359 name: osmosensor activity namespace: molecular_function xref: GO:0005034 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001360 name: death receptor activity namespace: molecular_function xref: GO:0005035 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001361 name: decoy death receptor activity namespace: molecular_function xref: GO:0005040 is_a: CCO:F0001360 ! death receptor activity [Term] id: CCO:F0001362 name: low-density lipoprotein receptor activity namespace: molecular_function def: "Combining with a low-density lipoprotein to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "LDL receptor" EXACT [] xref: GO:0005041 xref: GO:0008032 is_a: CCO:F0004336 ! low-density lipoprotein binding is_a: CCO:F0004351 ! lipoprotein receptor activity [Term] id: CCO:F0001363 name: netrin receptor activity namespace: molecular_function def: "A transmembrane receptor activity that responds to the netrin family of ligands and results in chemotaxis when activated." [GOC:dph] xref: GO:0005042 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001364 name: repulsive netrin receptor activity namespace: molecular_function def: "A transmembrane receptor activity that responds to the netrin family of ligands and results in chemorepulsion when activated." [GOC:dph] xref: GO:0005043 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001365 name: scavenger receptor activity namespace: molecular_function def: "Combining with acetylated low-density lipoproteins, advanced glycation end products, or other polyanionic ligands to initiate a change in cell activity." [PMID:11790542, PMID:12379907, PMID:12621157] comment: Note that many gene products that are called scavenger receptors have a broad range of potential ligands and also can be annotated to 'pattern recognition receptor activity ; GO:0008329' or its child terms, or to 'lipoprotein receptor activity ; GO:0030228' or its child terms. subset: gosubset_prok synonym: "macrophage receptor activity" EXACT [] xref: GO:0005044 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001366 name: KDEL sequence binding namespace: molecular_function def: "Interacting selectively with a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum." [GOC:ai] synonym: "KDEL receptor activity" NARROW [] xref: GO:0005046 is_a: CCO:F0006275 ! ER retention sequence binding [Term] id: CCO:F0001367 name: signal recognition particle binding namespace: molecular_function def: "Interacting selectively with the signal recognition particle." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: See also the cellular component term 'signal recognition particle, endoplasmic reticulum targeting ; GO:0005786'. subset: gosubset_prok synonym: "docking protein" BROAD [] synonym: "signal recognition particle receptor" NARROW [] xref: GO:0005047 is_a: CCO:F0005783 ! ribonucleoprotein binding [Term] id: CCO:F0001368 name: signal sequence binding namespace: molecular_function def: "Interacting selectively with a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized." [GOC:ai] subset: gosubset_prok synonym: "leader sequence binding" NARROW [] synonym: "protein signal sequence binding" NARROW [] synonym: "signal sequence receptor" NARROW [] xref: GO:0005048 xref: GO:0008249 is_a: CCO:F0005639 ! peptide binding [Term] id: CCO:F0001369 name: nuclear export signal receptor activity namespace: molecular_function def: "Combining with a nuclear export signal to initiate a change in cell activity." [GOC:ai] synonym: "NES receptor" EXACT [] xref: GO:0005049 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001370 name: peroxisome matrix targeting signal-1 binding namespace: molecular_function def: "Interacting selectively with a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L." [GOC:mah, PMID:11687502] synonym: "peroxisome targeting signal-1 binding" EXACT [] synonym: "peroxisome targeting signal-1 receptor" NARROW [] synonym: "PEX5" NARROW [] synonym: "PTS1 receptor" NARROW [] xref: GO:0005052 is_a: CCO:F0000054 ! peroxisome targeting sequence binding [Term] id: CCO:F0001371 name: peroxisome matrix targeting signal-2 binding namespace: molecular_function def: "Interacting selectively with a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F)." [GOC:mah, PMID:11687502] synonym: "peroxisome targeting signal-2 binding" EXACT [] synonym: "peroxisome targeting signal-2 receptor" NARROW [] synonym: "PEX7" NARROW [] synonym: "PTS2 receptor" EXACT [] xref: GO:0005053 is_a: CCO:F0000054 ! peroxisome targeting sequence binding [Term] id: CCO:F0001372 name: laminin receptor activity namespace: molecular_function def: "Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'. subset: gosubset_prok xref: GO:0005055 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001373 name: tiggrin receptor activity namespace: molecular_function xref: GO:0005056 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001374 name: receptor signaling protein activity namespace: molecular_function synonym: "receptor signalling protein activity" EXACT [] xref: GO:0005057 is_a: CCO:F0001225 ! signal transducer activity [Term] id: CCO:F0001375 name: aryl hydrocarbon receptor nuclear translocator activity namespace: molecular_function xref: GO:0005061 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001376 name: hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity namespace: molecular_function synonym: "gp130" NARROW [] xref: GO:0005062 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001377 name: transmembrane receptor protein tyrosine kinase signaling protein activity namespace: molecular_function synonym: "transmembrane receptor protein tyrosine kinase signalling protein activity" EXACT [] xref: GO:0005066 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001378 name: transmembrane receptor protein tyrosine kinase adaptor protein activity namespace: molecular_function def: "The binding activity of a molecule that brings together a transmembrane receptor protein kinase and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT] xref: GO:0005068 is_a: CCO:F0001377 ! transmembrane receptor protein tyrosine kinase signaling protein activity is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0001379 name: transmembrane receptor protein tyrosine kinase docking protein activity namespace: molecular_function xref: GO:0005069 is_a: CCO:F0001377 ! transmembrane receptor protein tyrosine kinase signaling protein activity [Term] id: CCO:F0001380 name: SH3/SH2 adaptor activity namespace: molecular_function def: "Interacting selectively and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68)." [GOC:mah, GOC:so] synonym: "SH3/SH2 adaptor protein activity" NARROW [] xref: GO:0005070 is_a: CCO:F0001225 ! signal transducer activity is_a: CCO:F0004516 ! protein binding, bridging is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0001381 name: transmembrane receptor protein serine/threonine kinase signaling protein activity namespace: molecular_function synonym: "transmembrane receptor protein serine/threonine kinase signalling protein activity" EXACT [] xref: GO:0005071 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001382 name: transforming growth factor beta receptor, cytoplasmic mediator activity namespace: molecular_function def: "Activity of any of the molecules that transmit the signal from a TGFbeta receptor through the cytoplasm to the nucleus." [GOC:hjd] comment: Note that this term and its children are useful for annotating proteins of the SMAD family. synonym: "TGF-beta receptor, cytoplasmic mediator activity" EXACT [] synonym: "TGFbeta receptor, cytoplasmic mediator activity" EXACT [] xref: GO:0005072 is_a: CCO:F0001381 ! transmembrane receptor protein serine/threonine kinase signaling protein activity [Term] id: CCO:F0001383 name: receptor signaling protein serine/threonine kinase signaling protein activity namespace: molecular_function synonym: "receptor signalling protein serine/threonine kinase signalling protein activity" EXACT [] xref: GO:0005076 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001384 name: MAP-kinase scaffold activity namespace: molecular_function def: "Functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. MAPK scaffold proteins have binding sites for MAPK pathway kinases as well as for upstream signaling proteins." [PMID:12511654] synonym: "MAP-kinase scaffold protein activity" EXACT [] xref: GO:0005078 is_a: CCO:F0004332 ! receptor signaling complex scaffold activity [Term] id: CCO:F0001385 name: protein kinase C binding namespace: molecular_function def: "Interacting selectively with protein kinase C." [GOC:jl] synonym: "PKC binding" EXACT [] xref: GO:0005080 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0001386 name: receptor signaling protein serine/threonine phosphatase signaling protein activity namespace: molecular_function synonym: "receptor signalling protein serine/threonine phosphatase signalling protein activity" EXACT [] xref: GO:0005081 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001387 name: receptor signaling protein tyrosine phosphatase signaling protein activity namespace: molecular_function synonym: "receptor signalling protein tyrosine phosphatase signalling protein activity" EXACT [] xref: GO:0005082 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001388 name: small GTPase regulator activity namespace: molecular_function def: "Modulates the rate of GTP hydrolysis by a small monomeric GTPase." [GOC:mah] subset: gosubset_prok synonym: "small GTPase regulatory/interacting protein activity" RELATED [] xref: GO:0005083 is_a: CCO:F0004520 ! GTPase regulator activity [Term] id: CCO:F0001390 name: guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:kd, GOC:mah] subset: gosubset_prok synonym: "GEF" EXACT [] synonym: "GNRP" NARROW [] synonym: "guanyl-nucleotide release factor activity" EXACT [] synonym: "guanyl-nucleotide releasing factor" EXACT [] xref: GO:0005085 xref: GO:0008433 xref: GO:0019839 xref: Reactome:11431 is_a: CCO:F0004520 ! GTPase regulator activity [Term] id: CCO:F0001391 name: ARF guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] xref: GO:0005086 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0001390 ! guanyl-nucleotide exchange factor activity [Term] id: CCO:F0001392 name: Ran guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase of the Ran family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] synonym: "RCC1" EXACT [] xref: GO:0005087 xref: Reactome:11435 is_a: CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity [Term] id: CCO:F0001393 name: Ras guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase of the Ras superfamily. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] xref: GO:0005088 xref: Reactome:11436 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0001390 ! guanyl-nucleotide exchange factor activity [Term] id: CCO:F0001394 name: Rho guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] synonym: "Rho guanine nucleotide exchange factor" EXACT [] synonym: "RhoGEF" EXACT [] xref: GO:0005089 is_a: CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity [Term] id: CCO:F0001395 name: Sar guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by the GTPase Sar. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] xref: GO:0005090 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0001390 ! guanyl-nucleotide exchange factor activity [Term] id: CCO:F0001396 name: guanyl-nucleotide exchange factor adaptor activity namespace: molecular_function def: "The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT] xref: GO:0005091 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0001397 name: GDP-dissociation inhibitor activity namespace: molecular_function def: "Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding." [GOC:mah] synonym: "GDI" EXACT [] xref: GO:0005092 is_a: CCO:F0001388 ! small GTPase regulator activity [Term] id: CCO:F0001398 name: Rab GDP-dissociation inhibitor activity namespace: molecular_function def: "Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding." [GOC:mah] xref: GO:0005093 is_a: CCO:F0001397 ! GDP-dissociation inhibitor activity [Term] id: CCO:F0001399 name: Rho GDP-dissociation inhibitor activity namespace: molecular_function def: "Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding." [GOC:mah] xref: GO:0005094 is_a: CCO:F0001397 ! GDP-dissociation inhibitor activity [Term] id: CCO:F0001400 name: GTPase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate." [GOC:ai] synonym: "GIP" BROAD [] xref: GO:0005095 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0004520 ! GTPase regulator activity [Term] id: CCO:F0001401 name: GTPase activator activity namespace: molecular_function def: "Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP." [GOC:mah] subset: gosubset_prok synonym: "GAP" BROAD [] xref: GO:0005096 xref: Reactome:11473 is_a: CCO:F0001691 ! enzyme activator activity is_a: CCO:F0004520 ! GTPase regulator activity [Term] id: CCO:F0001402 name: Rab GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by a GTPase of the Rab family." [GOC:mah] xref: GO:0005097 is_a: CCO:F0001404 ! Ras GTPase activator activity [Term] id: CCO:F0001403 name: Ran GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by a GTPase of the Ran family." [GOC:mah] synonym: "RanGAP" RELATED [] xref: GO:0005098 is_a: CCO:F0001404 ! Ras GTPase activator activity [Term] id: CCO:F0001404 name: Ras GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by a GTPase of the Ras superfamily." [GOC:mah] xref: GO:0005099 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0001401 ! GTPase activator activity [Term] id: CCO:F0001405 name: Rho GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by a GTPase of the Rho family." [GOC:mah] xref: GO:0005100 is_a: CCO:F0001404 ! Ras GTPase activator activity [Term] id: CCO:F0001406 name: Sar GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by the GTPase Sar." [GOC:mah] xref: GO:0005101 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0001401 ! GTPase activator activity [Term] id: CCO:F0001407 name: receptor binding namespace: molecular_function def: "Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." [GOC:bf, GOC:ceb, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_plant subset: gosubset_prok synonym: "adrenocorticotropin" RELATED [] synonym: "allatostatin" RELATED [] synonym: "insulin" RELATED [] synonym: "receptor ligand" NARROW [] synonym: "receptor-associated protein activity" RELATED [] xref: GO:0005102 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001408 name: baboon binding namespace: molecular_function def: "Interacting selectively with the baboon (babo) protein, a type I transforming growth factor beta receptor." [GOC:ceb] synonym: "babo binding" EXACT [] synonym: "babo ligand" NARROW [] synonym: "baboon ligand" NARROW [] synonym: "baboon receptor ligand" NARROW [] xref: GO:0005103 is_a: CCO:F0001462 ! transforming growth factor beta receptor binding [Term] id: CCO:F0001409 name: fibroblast growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the fibroblast growth factor receptor (FGFR)." [GOC:ceb] comment: Note that branchless is the Drosophila gene encoding fibroblast growth factor. synonym: "FGF receptor binding" EXACT [] synonym: "FGFR binding" EXACT [] synonym: "FGFR ligand" NARROW [] synonym: "fibroblast growth factor" BROAD [] synonym: "fibroblast growth factor receptor ligand" NARROW [] xref: GO:0001521 xref: GO:0005104 xref: GO:0005162 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001410 name: type 1 fibroblast growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the type 1 fibroblast growth factor receptor (FGFR1)." [GOC:ceb, GOC:fb_curators] comment: Note that breathless is the Drosophila gene encoding the type 1 fibroblast growth factor receptor (FGFR1). synonym: "breathless binding" NARROW [] synonym: "breathless ligand" NARROW [] synonym: "FGFR1 binding" BROAD [] synonym: "FGFR1 ligand" NARROW [] synonym: "type 1 fibroblast growth factor receptor ligand" NARROW [] xref: GO:0005105 is_a: CCO:F0001409 ! fibroblast growth factor receptor binding [Term] id: CCO:F0001411 name: frizzled binding namespace: molecular_function def: "Interacting selectively with the frizzled (fz) receptor." [GOC:ceb] synonym: "frizzled ligand" NARROW [] synonym: "fz binding" EXACT [] synonym: "fz ligand" NARROW [] xref: GO:0005109 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0001412 name: frizzled-2 binding namespace: molecular_function def: "Interacting selectively with frizzled-2 (fz2)." [GOC:ceb] synonym: "frizzled-2 ligand" NARROW [] synonym: "fz2 binding" EXACT [] synonym: "fz2 ligand" NARROW [] xref: GO:0005110 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0001413 name: type 2 fibroblast growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the type 2 fibroblast growth factor receptor (FGFR2)." [GOC:fb_curators] comment: Note that heartless is the Drosophila gene encoding the type 2 fibroblast growth factor receptor (FGFR2). synonym: "FGFR2 binding" EXACT [] synonym: "FGFR2 ligand" NARROW [] synonym: "heartless binding" EXACT [] synonym: "heartless ligand" NARROW [] synonym: "type 2 fibroblast growth factor receptor ligand" NARROW [] xref: GO:0005111 is_a: CCO:F0001409 ! fibroblast growth factor receptor binding [Term] id: CCO:F0001414 name: Notch binding namespace: molecular_function def: "Interacting selectively with the Notch (N) protein, a surface receptor." [GOC:ceb] synonym: "N binding" EXACT [] synonym: "N ligand" NARROW [] synonym: "Notch ligand" NARROW [] synonym: "Notch receptor binding" EXACT [] xref: GO:0005112 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001415 name: patched binding namespace: molecular_function def: "Interacting selectively with the patched (ptc) protein, a receptor for hedgehog proteins." [GOC:ceb, PMID:11731473] synonym: "patched ligand" NARROW [] synonym: "ptc binding" EXACT [] synonym: "ptc ligand" NARROW [] xref: GO:0005113 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001416 name: punt binding namespace: molecular_function def: "Interacting selectively with the punt protein, a type II transforming growth factor beta receptor." [GOC:bf] synonym: "punt ligand" NARROW [] synonym: "put binding" EXACT [] synonym: "put ligand" NARROW [] xref: GO:0005114 is_a: CCO:F0001462 ! transforming growth factor beta receptor binding [Term] id: CCO:F0001417 name: receptor tyrosine kinase-like orphan receptor binding namespace: molecular_function def: "Interaction with the receptor tyrosine kinase-like orphan receptor (Ror)." [GOC:ceb] synonym: "receptor tyrosine kinase-like orphan receptor ligand" NARROW [] synonym: "Ror binding" BROAD [] synonym: "Ror ligand" RELATED [] xref: GO:0005115 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001418 name: saxophone binding namespace: molecular_function def: "Interacting selectively with the saxophone (sax) protein, a type I transforming growth factor beta receptor." [GOC:ceb, PMID:11252892] synonym: "sax binding" EXACT [] synonym: "sax ligand" NARROW [] synonym: "saxophone ligand" NARROW [] xref: GO:0005116 is_a: CCO:F0001462 ! transforming growth factor beta receptor binding [Term] id: CCO:F0001419 name: wishful thinking binding namespace: molecular_function def: "Interacting selectively with wishful thinking (Wit), a type II bone morphogenic protein receptor." [GOC:ceb, PMID:11856529] synonym: "SE20 receptor binding" NARROW [] synonym: "wishful thinking ligand" NARROW [] synonym: "Wit binding" EXACT [] synonym: "Wit ligand" NARROW [] xref: GO:0005117 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001420 name: sevenless binding namespace: molecular_function def: "Interacting selectively with the sevenless (sev) protein, a receptor tyrosine kinase." [FB:gn0003366, GOC:ceb] synonym: "sev binding" EXACT [] synonym: "sev ligand" NARROW [] synonym: "sevenless ligand" NARROW [] xref: GO:0005118 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001421 name: smoothened binding namespace: molecular_function def: "Interacting selectively with the smoothened (smo) protein, which interacts with patched to transmit hedgehog signals." [GOC:ceb, PMID:11731473] synonym: "smo binding" EXACT [] synonym: "smo ligand" NARROW [] synonym: "smoothened ligand" NARROW [] xref: GO:0005119 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001422 name: thickveins binding namespace: molecular_function def: "Interacting selectively with the thickveins (tkv) protein, a type I transforming growth factor beta receptor." [GOC:ceb, PMID:11252892] synonym: "thickveins ligand" NARROW [] synonym: "tkv binding" EXACT [] synonym: "tkv ligand" NARROW [] xref: GO:0005120 is_a: CCO:F0001462 ! transforming growth factor beta receptor binding [Term] id: CCO:F0001423 name: Toll binding namespace: molecular_function def: "Interacting selectively with the Toll protein, a transmembrane receptor." [GOC:ceb] synonym: "Tl binding" EXACT [] synonym: "Toll ligand" NARROW [] synonym: "Toll receptor binding" EXACT [] xref: GO:0005121 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001424 name: torso binding namespace: molecular_function def: "Interacting selectively with the torso (tor) protein, a receptor tyrosine kinase." [FB:gn0003733, GOC:ceb] synonym: "tor binding" EXACT [] synonym: "tor ligand" NARROW [] synonym: "torso ligand" NARROW [] xref: GO:0005122 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001425 name: death receptor binding namespace: molecular_function def: "Interacting selectively with a death receptor." [GOC:ceb] synonym: "death receptor adaptor protein activity" RELATED [] synonym: "death receptor interacting protein activity" RELATED [] synonym: "death receptor ligand" NARROW [] synonym: "death receptor-associated factor activity" RELATED [] xref: GO:0005123 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001426 name: scavenger receptor binding namespace: molecular_function def: "Interacting selectively with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles." [GOC:ceb] synonym: "scavenger receptor ligand" NARROW [] xref: GO:0005124 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001427 name: cytokine activity namespace: molecular_function def: "Functions to control the survival, growth, differentiation and effector function of tissues and cells." [ISBN:0198599471] xref: GO:0005125 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001428 name: hematopoietin/interferon-class (D200-domain) cytokine receptor binding namespace: molecular_function synonym: "hematopoietin/interferon-class (D200-domain) cytokine receptor ligand" NARROW [] xref: GO:0005126 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001429 name: ciliary neurotrophic factor receptor binding namespace: molecular_function def: "Interacting selectively with the ciliary neurotrophic factor receptor." [GOC:ai] synonym: "ciliary neurotrophic factor" NARROW [] synonym: "ciliary neurotrophic factor receptor ligand" NARROW [] xref: GO:0005127 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001430 name: erythropoietin receptor binding namespace: molecular_function def: "Interacting selectively with the erythropoietin receptor." [GOC:ai] synonym: "erythropoietin" NARROW [] synonym: "erythropoietin receptor ligand" NARROW [] xref: GO:0005128 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001431 name: granulocyte macrophage colony-stimulating factor receptor binding namespace: molecular_function def: "Interacting selectively with the granulocyte macrophage colony-stimulating factor receptor." [GOC:ai] synonym: "GM-CSF receptor ligand" NARROW [] synonym: "GMC-SF receptor ligand" NARROW [] synonym: "granulocyte macrophage colony-stimulating factor receptor ligand" NARROW [] synonym: "granulocyte-macrophage colony stimulating factor" NARROW [] xref: GO:0005129 is_a: CCO:F0001430 ! erythropoietin receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001432 name: granulocyte colony-stimulating factor receptor binding namespace: molecular_function def: "Interacting selectively with the granulocyte colony-stimulating factor receptor." [GOC:ai] synonym: "G-CSF receptor ligand" EXACT [] synonym: "GC-SF receptor ligand" EXACT [] synonym: "granulocyte colony-stimulating factor" NARROW [] synonym: "granulocyte colony-stimulating factor receptor ligand" NARROW [] xref: GO:0005130 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001433 name: growth hormone receptor binding namespace: molecular_function def: "Interacting selectively with the growth hormone receptor." [GOC:ai] synonym: "growth hormone" NARROW [] synonym: "growth hormone receptor ligand" NARROW [] xref: GO:0005131 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001434 name: interferon-alpha/beta receptor binding namespace: molecular_function def: "Interacting selectively with the interferon-alpha/beta receptor." [GOC:ai] synonym: "interferon-alpha/beta" NARROW [] synonym: "interferon-alpha/beta receptor ligand" NARROW [] xref: GO:0005132 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001435 name: interferon-gamma receptor binding namespace: molecular_function def: "Interacting selectively with the interferon-gamma receptor." [GOC:ai] synonym: "interferon-gamma" NARROW [] synonym: "interferon-gamma receptor ligand" NARROW [] xref: GO:0005133 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001436 name: interleukin-2 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-2 receptor." [GOC:ai] synonym: "IL-2" NARROW [] synonym: "interleukin-2 receptor ligand" NARROW [] xref: GO:0005134 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001437 name: interleukin-3 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-3 receptor." [GOC:ai] synonym: "IL-3" NARROW [] synonym: "interleukin-3 receptor ligand" NARROW [] xref: GO:0005135 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001438 name: interleukin-4 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-4 receptor." [GOC:ai] synonym: "IL-4" NARROW [] synonym: "interleukin-4 receptor ligand" NARROW [] xref: GO:0005136 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001439 name: interleukin-5 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-5 receptor." [GOC:ai] synonym: "IL-5" NARROW [] synonym: "interleukin-5 receptor ligand" NARROW [] xref: GO:0005137 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001440 name: interleukin-6 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-6 receptor." [GOC:ai] synonym: "IL-6" NARROW [] synonym: "interleukin-6 receptor ligand" NARROW [] xref: GO:0005138 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001441 name: interleukin-7 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-7 receptor." [GOC:ai] synonym: "IL-7" NARROW [] synonym: "interleukin-7 receptor ligand" NARROW [] xref: GO:0005139 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001442 name: interleukin-9 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-9 receptor." [GOC:ai] synonym: "IL-9" NARROW [] synonym: "interleukin-9 receptor ligand" NARROW [] xref: GO:0005140 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001443 name: interleukin-10 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-10 receptor." [GOC:ai] synonym: "IL-10" NARROW [] synonym: "interleukin-10 receptor ligand" NARROW [] xref: GO:0005141 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001444 name: interleukin-11 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-11 receptor." [GOC:ai] synonym: "IL-11" NARROW [] synonym: "interleukin-11 receptor ligand" NARROW [] xref: GO:0005142 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001445 name: interleukin-12 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-12 receptor." [GOC:ai] synonym: "IL-12" NARROW [] synonym: "interleukin-12 receptor ligand" NARROW [] xref: GO:0005143 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001446 name: interleukin-13 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-13 receptor." [GOC:ai] synonym: "IL-13" NARROW [] synonym: "interleukin-13 receptor ligand" NARROW [] xref: GO:0005144 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001447 name: interleukin-14 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-14 receptor." [GOC:ai] synonym: "IL-14" NARROW [] synonym: "interleukin-14 receptor ligand" NARROW [] xref: GO:0005145 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001448 name: leukemia inhibitory factor receptor binding namespace: molecular_function def: "Interacting selectively with the leukemia inhibitory factor receptor." [GOC:ai] synonym: "leukemia inhibitory factor" NARROW [] synonym: "leukemia inhibitory factor receptor ligand" NARROW [] xref: GO:0005146 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001449 name: oncostatin-M receptor binding namespace: molecular_function def: "Interacting selectively with the oncostatin-M receptor." [GOC:ai] synonym: "oncostatin-M" NARROW [] synonym: "oncostatin-M receptor ligand" NARROW [] xref: GO:0005147 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001450 name: prolactin receptor binding namespace: molecular_function def: "Interacting selectively with the prolactin receptor." [GOC:ai] synonym: "prolactin" NARROW [] synonym: "prolactin receptor ligand" NARROW [] xref: GO:0005148 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0001451 name: interleukin-1 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-1 receptor." [GOC:go_curators] synonym: "IL-1" NARROW [] synonym: "interleukin-1 receptor ligand" NARROW [] xref: GO:0005149 is_a: CCO:F0001427 ! cytokine activity is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001452 name: interleukin-1, Type I receptor binding namespace: molecular_function def: "Interacting selectively with a Type I interleukin-1 receptor." [GOC:ai] synonym: "IL-1 type I" NARROW [] synonym: "interleukin-1, Type I receptor ligand" NARROW [] xref: GO:0005150 is_a: CCO:F0001451 ! interleukin-1 receptor binding [Term] id: CCO:F0001453 name: interleukin-1, Type II receptor binding namespace: molecular_function def: "Interacting selectively with a Type II interleukin-1 receptor." [GOC:ai] synonym: "IL-1 type II" NARROW [] synonym: "interleukin-1, Type II receptor ligand" NARROW [] xref: GO:0005151 is_a: CCO:F0001451 ! interleukin-1 receptor binding [Term] id: CCO:F0001454 name: interleukin-1 receptor antagonist activity namespace: molecular_function def: "Blocks the binding of interleukin-1 to the interleukin-1 receptor complex." [GOC:ebc] synonym: "IL-1ra" EXACT [] xref: GO:0005152 is_a: CCO:F0001451 ! interleukin-1 receptor binding is_a: CCO:F0004407 ! fibroblast growth factor receptor antagonist activity [Term] id: CCO:F0001455 name: interleukin-8 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-8 receptor." [GOC:go_curators] synonym: "IL-8" NARROW [] synonym: "interleukin-8 receptor ligand" NARROW [] xref: GO:0005153 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001456 name: epidermal growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the epidermal growth factor receptor." [GOC:ai] synonym: "EGF" NARROW [] synonym: "EGF receptor binding" EXACT [] synonym: "EGF receptor ligand" NARROW [] synonym: "EGFR binding" EXACT [] synonym: "epidermal growth factor" NARROW [] synonym: "epidermal growth factor receptor ligand" NARROW [] synonym: "TGF-alpha receptor binding" EXACT [] synonym: "TGFalpha receptor binding" EXACT [] synonym: "transforming growth factor alpha" NARROW [] synonym: "transforming growth factor alpha receptor binding" EXACT [] synonym: "transforming growth factor alpha receptor ligand" NARROW [] xref: GO:0005154 xref: GO:0008185 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001457 name: epidermal growth factor receptor activating ligand activity namespace: molecular_function synonym: "EGF receptor activating ligand activity" EXACT [] synonym: "EGFR activating ligand activity" EXACT [] xref: GO:0005155 is_a: CCO:F0001456 ! epidermal growth factor receptor binding [Term] id: CCO:F0001458 name: epidermal growth factor receptor inhibiting ligand activity namespace: molecular_function synonym: "EGF receptor inhibiting ligand activity" EXACT [] synonym: "EGFR inhibiting ligand activity" EXACT [] xref: GO:0005156 is_a: CCO:F0001456 ! epidermal growth factor receptor binding [Term] id: CCO:F0001459 name: macrophage colony stimulating factor receptor binding namespace: molecular_function def: "Interacting selectively with the macrophage colony stimulating factor receptor." [GOC:ai] synonym: "macrophage colony stimulating factor receptor ligand" NARROW [] xref: GO:0005157 is_a: CCO:F0001427 ! cytokine activity is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001460 name: insulin receptor binding namespace: molecular_function def: "Interacting selectively with the insulin receptor." [GOC:ai] synonym: "insulin receptor ligand" NARROW [] xref: GO:0005158 is_a: CCO:F0001407 ! receptor binding is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0001461 name: insulin-like growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the insulin-like growth factor receptor." [GOC:jl] synonym: "IGF receptor binding" EXACT [] synonym: "insulin-like growth factor" NARROW [] synonym: "insulin-like growth factor receptor ligand" NARROW [] xref: GO:0005067 xref: GO:0005159 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001462 name: transforming growth factor beta receptor binding namespace: molecular_function def: "Interacting selectively with the transforming growth factor beta receptor." [GOC:ai] synonym: "activin" RELATED [] synonym: "inhibin" RELATED [] synonym: "TGF-beta receptor binding" EXACT [] synonym: "TGFbeta receptor binding" EXACT [] synonym: "transforming growth factor beta" NARROW [] synonym: "transforming growth factor beta ligand binding to type I receptor" RELATED [] synonym: "transforming growth factor beta ligand binding to type II receptor" RELATED [] synonym: "transforming growth factor beta receptor anchoring activity" RELATED [] synonym: "transforming growth factor beta receptor ligand" NARROW [] xref: GO:0005160 xref: Reactome:4078 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001463 name: platelet-derived growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the platelet-derived growth factor receptor." [GOC:ai] synonym: "PDGF" NARROW [] synonym: "PDGF receptor binding" EXACT [] synonym: "PDGFR binding" EXACT [] synonym: "platelet-derived growth factor" NARROW [] synonym: "platelet-derived growth factor receptor ligand" NARROW [] xref: GO:0005161 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001464 name: nerve growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the nerve growth factor receptor." [GOC:ai] synonym: "nerve growth factor receptor ligand" NARROW [] synonym: "neurotrophin" NARROW [] synonym: "NGF receptor binding" EXACT [] xref: GO:0005163 is_a: CCO:F0001466 ! neurotrophin receptor binding [Term] id: CCO:F0001465 name: tumor necrosis factor receptor binding namespace: molecular_function def: "Interacting selectively with the tumor necrosis factor receptor." [GOC:ai] synonym: "TNF receptor binding" EXACT [] synonym: "tumor necrosis factor" NARROW [] synonym: "tumor necrosis factor receptor ligand" NARROW [] xref: GO:0005164 is_a: CCO:F0005041 ! tumor necrosis factor receptor superfamily binding [Term] id: CCO:F0001466 name: neurotrophin receptor binding namespace: molecular_function def: "Interacting selectively with a neurotrophin receptor." [GOC:ai] synonym: "neurotrophin" NARROW [] synonym: "neurotrophin receptor ligand" NARROW [] xref: GO:0005165 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001467 name: neurotrophin p75 receptor binding namespace: molecular_function def: "Interacting selectively with the neurotrophin p75 receptor." [GOC:ai] synonym: "neurotrophin p75 receptor ligand" NARROW [] xref: GO:0005166 is_a: CCO:F0001466 ! neurotrophin receptor binding [Term] id: CCO:F0001468 name: neurotrophin TRK receptor binding namespace: molecular_function def: "Interacting selectively with a neurotrophin TRK receptor." [GOC:ai] synonym: "neurotrophin TRK receptor ligand" NARROW [] xref: GO:0005167 is_a: CCO:F0001466 ! neurotrophin receptor binding [Term] id: CCO:F0001469 name: neurotrophin TRKA receptor binding namespace: molecular_function def: "Interacting selectively with the neurotrophin TRKA receptor." [GOC:ai] synonym: "neurotrophin TRKA receptor ligand" NARROW [] xref: GO:0005168 is_a: CCO:F0001468 ! neurotrophin TRK receptor binding [Term] id: CCO:F0001470 name: neurotrophin TRKB receptor binding namespace: molecular_function def: "Interacting selectively with the neurotrophin TRKB receptor." [GOC:ai] synonym: "neurotrophin TRKB receptor ligand" NARROW [] xref: GO:0005169 is_a: CCO:F0001468 ! neurotrophin TRK receptor binding [Term] id: CCO:F0001471 name: neurotrophin TRKC receptor binding namespace: molecular_function def: "Interacting selectively with the neurotrophin TRKC receptor." [GOC:ai] synonym: "neurotrophin TRKC receptor ligand" NARROW [] xref: GO:0005170 is_a: CCO:F0001468 ! neurotrophin TRK receptor binding [Term] id: CCO:F0001472 name: hepatocyte growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the hepatocyte growth factor receptor." [GOC:ai] synonym: "hepatocyte growth factor" NARROW [] synonym: "hepatocyte growth factor receptor ligand" NARROW [] synonym: "HGF receptor binding" EXACT [] xref: GO:0005171 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001473 name: vascular endothelial growth factor receptor binding namespace: molecular_function def: "Interacting selectively with any vascular endothelial growth factor receptor." [GOC:ai] synonym: "vascular endothelial growth factor" NARROW [] synonym: "vascular endothelial growth factor receptor ligand" NARROW [] xref: GO:0005172 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001474 name: stem cell factor receptor binding namespace: molecular_function def: "Interacting selectively with the stem cell factor receptor (SCFR), a type III transmembrane kinase receptor." [GOC:jl, PMID:10698217] synonym: "KIT binding" NARROW [] synonym: "SCF" NARROW [] synonym: "SCFR binding" EXACT [] synonym: "stem cell factor" NARROW [] synonym: "stem cell factor receptor ligand" NARROW [] xref: GO:0005173 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0001475 name: CD40 receptor binding namespace: molecular_function def: "Interacting selectively with CD40, a receptor found on the surface of all B-lymphocytes." [GOC:jl, ISBN:0120781859] xref: GO:0005174 is_a: CCO:F0005041 ! tumor necrosis factor receptor superfamily binding [Term] id: CCO:F0001476 name: CD27 receptor binding namespace: molecular_function def: "Interacting selectively with a CD27, a receptor found on the surface of T cells and some B cells and NK cells." [GOC:jl, ISBN:0120781859] xref: GO:0005175 is_a: CCO:F0005041 ! tumor necrosis factor receptor superfamily binding [Term] id: CCO:F0001477 name: ErbB-2 class receptor binding namespace: molecular_function def: "Interacting selectively with the protein-tyrosine kinase receptor Neu/ErbB-2/HER2." [GOC:jl] synonym: "ErbB-2 class receptor ligand" NARROW [] synonym: "HER2 receptor binding" EXACT [] synonym: "HER2 receptor ligand" NARROW [] synonym: "Neu receptor binding" EXACT [] synonym: "Neu receptor ligand" NARROW [] xref: GO:0005176 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001478 name: integrin binding namespace: molecular_function def: "Interacting selectively with an integrin." [GOC:ceb] synonym: "integrin ligand" NARROW [] xref: GO:0005178 is_a: CCO:F0001407 ! receptor binding is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0001479 name: hormone activity namespace: molecular_function def: "The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "cAMP generating peptide activity" NARROW [] synonym: "glycopeptide hormone" NARROW [] synonym: "lipopeptide hormone" NARROW [] synonym: "peptide hormone" NARROW [] xref: GO:0005179 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001480 name: luteinizing hormone-releasing factor activity namespace: molecular_function xref: GO:0005183 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0001481 name: neuropeptide hormone activity namespace: molecular_function def: "The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones." [GOC:mah] synonym: "neurohormone" EXACT [] xref: GO:0005184 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0001482 name: neurohypophyseal hormone activity namespace: molecular_function xref: GO:0005185 is_a: CCO:F0001481 ! neuropeptide hormone activity [Term] id: CCO:F0001483 name: pheromone activity namespace: molecular_function def: "The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant." [GOC:sgd_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005186 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001484 name: structural molecule activity namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell." [GOC:mah] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0005198 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0001485 name: structural constituent of cell wall namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a cell wall." [GOC:mah] subset: gosubset_prok xref: GO:0005199 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001486 name: structural constituent of cytoskeleton namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a cytoskeletal structure." [GOC:mah] subset: gosubset_prok xref: GO:0005200 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001487 name: extracellular matrix structural constituent namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the extracellular matrix." [GOC:mah] subset: gosubset_prok synonym: "extracellular matrix glycoprotein" NARROW [] xref: GO:0005201 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001488 name: structural constituent of eye lens namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the lens of an eye." [GOC:mah] xref: GO:0005212 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001489 name: structural constituent of chorion namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a chorion." [GOC:mah, GOC:sensu] synonym: "structural constituent of chorion (sensu Insecta)" EXACT [] synonym: "structural protein of chorion (sensu Drosophila)" NARROW [] xref: GO:0005213 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001490 name: structural constituent of chitin-based cuticle namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a chitin-based cuticle." [GOC:mah, GOC:mtg_sensu] synonym: "structural constituent of cuticle (sensu Insecta)" EXACT [] xref: GO:0005214 is_a: CCO:F0005657 ! structural constituent of cuticle [Term] id: CCO:F0001491 name: transporter activity namespace: molecular_function def: "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells." [GOC:ai, GOC:df] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "small-molecule carrier or transporter" RELATED [] xref: GO:0005215 xref: GO:0005478 xref: Reactome:1391 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0001492 name: ion channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:cy, GOC:mtg_transport, ISBN:0815340729] subset: goslim_generic subset: gosubset_prok xref: GO:0005216 is_a: CCO:F0002557 ! ion transmembrane transporter activity is_a: CCO:F0004269 ! substrate specific channel activity [Term] id: CCO:F0001493 name: intracellular ligand-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0005217 is_a: CCO:F0002733 ! ligand-gated ion channel activity [Term] id: CCO:F0001494 name: intracellular ligand-gated calcium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0005218 is_a: CCO:F0001493 ! intracellular ligand-gated ion channel activity is_a: CCO:F0002735 ! calcium-release channel activity [Term] id: CCO:F0001495 name: ryanodine-sensitive calcium-release channel activity namespace: molecular_function synonym: "caffeine-sensitive calcium-release channel" RELATED [] synonym: "ryanodine receptor" NARROW [] xref: GO:0005219 is_a: CCO:F0001494 ! intracellular ligand-gated calcium channel activity [Term] id: CCO:F0001496 name: inositol 1,4,5-triphosphate-sensitive calcium-release channel activity namespace: molecular_function xref: GO:0005220 is_a: CCO:F0001493 ! intracellular ligand-gated ion channel activity is_a: CCO:F0002735 ! calcium-release channel activity [Term] id: CCO:F0001497 name: intracellular cyclic nucleotide activated cation channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport] xref: GO:0005221 is_a: CCO:F0001493 ! intracellular ligand-gated ion channel activity is_a: CCO:F0001524 ! cation channel activity is_a: CCO:F0006017 ! cyclic nucleotide-gated ion channel activity [Term] id: CCO:F0001498 name: intracellular cAMP activated cation channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport] synonym: "intracellular 3',5' cAMP activated cation channel activity" EXACT [] synonym: "intracellular 3',5'-cAMP activated cation channel activity" EXACT [] synonym: "intracellular adenosine 3',5'-cyclophosphate activated cation channel activity" EXACT [] synonym: "intracellular cyclic AMP activated cation channel activity" EXACT [] xref: GO:0005222 is_a: CCO:F0001497 ! intracellular cyclic nucleotide activated cation channel activity [Term] id: CCO:F0001499 name: intracellular cGMP activated cation channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport] xref: GO:0005223 is_a: CCO:F0001497 ! intracellular cyclic nucleotide activated cation channel activity [Term] id: CCO:F0001500 name: ATP-binding and phosphorylation-dependent chloride channel activity namespace: molecular_function xref: GO:0005224 is_a: CCO:F0001493 ! intracellular ligand-gated ion channel activity is_a: CCO:F0001522 ! chloride channel activity [Term] id: CCO:F0001501 name: volume-sensitive anion channel activity namespace: molecular_function synonym: "volume-regulated channel" BROAD [] xref: GO:0005225 is_a: CCO:F0001521 ! anion channel activity [Term] id: CCO:F0001502 name: calcium activated cation channel activity namespace: molecular_function def: "Catalysis of the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient." [GOC:dph, GOC:mtg_transport] synonym: "intracellular calcium-activated potassium channel" NARROW [] synonym: "polycystin" NARROW [] xref: GO:0005227 is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0001503 name: intracellular sodium activated potassium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification." [GOC:mtg_transport, PMID:12628167] xref: GO:0005228 is_a: CCO:F0001526 ! potassium channel activity is_a: CCO:F0004270 ! ion gated channel activity [Term] id: CCO:F0001504 name: intracellular calcium activated chloride channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport] xref: GO:0005229 is_a: CCO:F0001522 ! chloride channel activity is_a: CCO:F0004270 ! ion gated channel activity [Term] id: CCO:F0001505 name: extracellular ligand-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0005230 is_a: CCO:F0002733 ! ligand-gated ion channel activity [Term] id: CCO:F0001506 name: excitatory extracellular ligand-gated ion channel activity namespace: molecular_function subset: gosubset_prok xref: GO:0005231 is_a: CCO:F0001505 ! extracellular ligand-gated ion channel activity [Term] id: CCO:F0001507 name: serotonin-activated cation-selective channel activity namespace: molecular_function comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'serotonin receptor activity ; GO:0004993'. synonym: "5-hydroxytryptamine-gated receptor-channel" EXACT [] xref: GO:0005232 is_a: CCO:F0001506 ! excitatory extracellular ligand-gated ion channel activity is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0001508 name: extracellular-glutamate-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'. subset: gosubset_prok xref: GO:0005234 is_a: CCO:F0001506 ! excitatory extracellular ligand-gated ion channel activity [Term] id: CCO:F0001509 name: inhibitory extracellular ligand-gated ion channel activity namespace: molecular_function xref: GO:0005237 is_a: CCO:F0001505 ! extracellular ligand-gated ion channel activity [Term] id: CCO:F0001510 name: inward rectifier potassium channel activity namespace: molecular_function subset: gosubset_prok xref: GO:0005242 is_a: CCO:F0001517 ! voltage-gated potassium channel activity [Term] id: CCO:F0001511 name: gap junction channel activity namespace: molecular_function def: "A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes." [GOC:dgh, GOC:mtg_transport, ISBN:0815340729] synonym: "connexin" RELATED [] synonym: "innexin" NARROW [] synonym: "innexin channel activity" EXACT [] synonym: "intercellular channel" BROAD [] xref: GO:0005243 xref: GO:0015285 xref: GO:0015286 is_a: CCO:F0004262 ! wide pore channel activity [Term] id: CCO:F0001512 name: voltage-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "voltage gated ion channel activity" EXACT [] synonym: "voltage-dependent ion channel activity" EXACT [] xref: GO:0005244 is_a: CCO:F0001492 ! ion channel activity is_a: CCO:F0004264 ! voltage-gated channel activity [Term] id: CCO:F0001513 name: voltage-gated calcium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel." [GOC:mtg_transport, GOC:tb, ISBN:0815340729] synonym: "depolarisation-activated calcium channel" BROAD [] synonym: "depolarisation-activated voltage-gated calcium channel" EXACT [] synonym: "depolarization-activated calcium channel" BROAD [] synonym: "depolarization-activated voltage gated calcium channel activity" EXACT [] synonym: "depolarization-activated voltage-gated calcium channel activity" EXACT [] synonym: "voltage gated calcium channel activity" EXACT [] synonym: "voltage-dependent calcium channel activity" EXACT [] synonym: "voltage-gated calcium ion channel activity" EXACT [] synonym: "voltage-sensitive calcium channel" EXACT [] xref: GO:0005245 xref: GO:0010173 is_a: CCO:F0001525 ! calcium channel activity is_a: CCO:F0004274 ! voltage-gated cation channel activity [Term] id: CCO:F0001514 name: calcium channel regulator activity namespace: molecular_function xref: GO:0005246 is_a: CCO:F0003086 ! channel regulator activity [Term] id: CCO:F0001515 name: voltage-gated chloride channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a chloride ion by a voltage-gated channel." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "voltage gated chloride channel activity" EXACT [] synonym: "voltage-dependent chloride channel activity" EXACT [] xref: GO:0005247 is_a: CCO:F0001522 ! chloride channel activity is_a: CCO:F0001822 ! voltage-gated anion channel activity [Term] id: CCO:F0001516 name: voltage-gated sodium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel." [GOC:mtg_transport, ISBN:0815340729] synonym: "voltage gated sodium channel activity" EXACT [] synonym: "voltage-dependent sodium channel activity" EXACT [] synonym: "voltage-gated sodium ion channel activity" EXACT [] synonym: "voltage-sensitive sodium channel" EXACT [] xref: GO:0005248 is_a: CCO:F0001527 ! sodium channel activity is_a: CCO:F0004274 ! voltage-gated cation channel activity [Term] id: CCO:F0001517 name: voltage-gated potassium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "voltage gated potassium channel activity" EXACT [] synonym: "voltage-dependent potassium channel activity" EXACT [] synonym: "voltage-gated potassium ion channel activity" EXACT [] synonym: "voltage-sensitive potassium channel" EXACT [] xref: GO:0005249 is_a: CCO:F0001526 ! potassium channel activity is_a: CCO:F0004274 ! voltage-gated cation channel activity [Term] id: CCO:F0001518 name: A-type (transient outward) potassium channel activity namespace: molecular_function xref: GO:0005250 is_a: CCO:F0002728 ! outward rectifier potassium channel activity [Term] id: CCO:F0001519 name: delayed rectifier potassium channel activity namespace: molecular_function xref: GO:0005251 is_a: CCO:F0001517 ! voltage-gated potassium channel activity [Term] id: CCO:F0001520 name: open rectifier potassium channel activity namespace: molecular_function xref: GO:0005252 is_a: CCO:F0001517 ! voltage-gated potassium channel activity [Term] id: CCO:F0001521 name: anion channel activity namespace: molecular_function def: "Catalysis of the energy-independent passage of anions across a lipid bilayer down a concentration gradient." [GOC:dph, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0005253 is_a: CCO:F0001492 ! ion channel activity is_a: CCO:F0001962 ! anion transmembrane transporter activity [Term] id: CCO:F0001522 name: chloride channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of an chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0005254 is_a: CCO:F0001521 ! anion channel activity [Term] id: CCO:F0001523 name: channel-conductance-controlling ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. It is also involved in the functioning of other transmembrane channels." [EC:3.6.3.49] synonym: "ATP phosphohydrolase (channel-conductance-controlling)" EXACT [EC:3.6.3.49] synonym: "cystic fibrosis transmembrane conductance regulator" NARROW [] synonym: "cystic-fibrosis membrane-conductance-regulating protein activity" NARROW [EC:3.6.3.49] xref: EC:3.6.3.49 xref: GO:0005260 xref: MetaCyc:3.6.3.49-RXN is_a: CCO:F0001522 ! chloride channel activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0001524 name: cation channel activity namespace: molecular_function def: "Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient." [GOC:def, GOC:dph, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "cation diffusion facilitator activity" EXACT [] synonym: "nonselective cation channel activity" EXACT [] xref: GO:0005261 xref: GO:0015281 xref: GO:0015338 is_a: CCO:F0001492 ! ion channel activity is_a: CCO:F0001835 ! cation transmembrane transporter activity is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0001525 name: calcium channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of an calcium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0005262 xref: Reactome:13088 is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0001526 name: potassium channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0005267 is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0001527 name: sodium channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0005272 is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0001528 name: allantoin uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.39.3.1] synonym: "allantoin permease activity" RELATED [] synonym: "allantoin/allantoate transporter" BROAD [] xref: GO:0005274 xref: GO:0015206 is_a: CCO:F0002815 ! nucleobase:cation symporter activity is_a: CCO:F0002943 ! uptake transmembrane transporter activity [Term] id: CCO:F0001529 name: amine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "amine/amide/polyamine channel activity" BROAD [] synonym: "amine/polyamine transmembrane transporter activity" EXACT [] synonym: "amino acid-polyamine transmembrane transporter activity" EXACT [] xref: GO:0005275 xref: GO:0005279 is_a: CCO:F0004251 ! active transmembrane transporter activity [Term] id: CCO:F0001530 name: hydrogen:vesicular amine antiporter activity namespace: molecular_function xref: GO:0005276 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0002748 ! solute:hydrogen antiporter activity [Term] id: CCO:F0001531 name: acetylcholine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of acetylcholine from one side of the membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] xref: GO:0005277 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0001559 ! neurotransmitter transporter activity [Term] id: CCO:F0001532 name: acetylcholine:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out)." [TC:2.A.1.2.13] synonym: "acetylcholine:proton antiporter" EXACT [] xref: GO:0005278 is_a: CCO:F0001531 ! acetylcholine transmembrane transporter activity is_a: CCO:F0002748 ! solute:hydrogen antiporter activity [Term] id: CCO:F0001533 name: hydrogen:amino acid symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in)." [GOC:ai] subset: gosubset_prok synonym: "cation/amino acid symporter" BROAD [] xref: GO:0005280 is_a: CCO:F0001608 ! cation:amino acid symporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity [Term] id: CCO:F0001534 name: sodium:amino acid symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in)." [GOC:ai] subset: gosubset_prok synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] synonym: "isoleucine/valine:sodium symporter activity" NARROW [] synonym: "sodium/amino acid transporter" EXACT [] synonym: "sodium/excitatory amino acid cotransporter activity" EXACT [] synonym: "sodium/excitatory amino acid symporter activity" EXACT [] synonym: "sodium:amino acid transporter activity" EXACT [] synonym: "threonine/serine:sodium symporter activity" NARROW [] xref: GO:0005283 xref: GO:0005285 is_a: CCO:F0001571 ! organic acid:sodium symporter activity is_a: CCO:F0001608 ! cation:amino acid symporter activity [Term] id: CCO:F0001535 name: insulin-activated sodium:amino acid symporter activity namespace: molecular_function synonym: "insulin-activated sodium/amino acid transporter activity" EXACT [] synonym: "insulin-activated sodium:amino acid transporter activity" EXACT [] xref: GO:0005284 is_a: CCO:F0001534 ! sodium:amino acid symporter activity [Term] id: CCO:F0001536 name: high affinity basic amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] synonym: "high-affinity basic amino acid transporter activity" BROAD [] xref: GO:0005287 is_a: CCO:F0002651 ! basic amino acid transmembrane transporter activity [Term] id: CCO:F0001537 name: high affinity arginine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of arginine from one side of a membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] synonym: "high-affinity arginine transporter activity" BROAD [] xref: GO:0005289 is_a: CCO:F0001536 ! high affinity basic amino acid transmembrane transporter activity is_a: CCO:F0002655 ! arginine transmembrane transporter activity [Term] id: CCO:F0001538 name: L-histidine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] synonym: "L-histidine transporter activity" BROAD [] xref: GO:0005290 is_a: CCO:F0002651 ! basic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0001539 name: high affinity L-histidine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] synonym: "high affinity histidine permease activity" RELATED [] xref: GO:0005291 is_a: CCO:F0001536 ! high affinity basic amino acid transmembrane transporter activity is_a: CCO:F0001538 ! L-histidine transmembrane transporter activity [Term] id: CCO:F0001540 name: high affinity lysine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of lysine from one side of a membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] synonym: "high affinity lysine transporter activity" BROAD [] xref: GO:0005292 is_a: CCO:F0001536 ! high affinity basic amino acid transmembrane transporter activity is_a: CCO:F0002663 ! L-lysine transmembrane transporter activity [Term] id: CCO:F0001541 name: neutral L-amino acid secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] subset: gosubset_prok synonym: "neutral L-amino acid porter activity" RELATED [] xref: GO:0005294 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001542 name: neutral amino acid:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in)." [TC:2.A.23.3.1] synonym: "neutral amino acid-sodium cotransporter" BROAD [] synonym: "sodium/neutral amino acid transporter" BROAD [] xref: GO:0005282 xref: GO:0005295 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity [Term] id: CCO:F0001543 name: hydrogen:proline symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in)." [GOC:ai] synonym: "hydrogen/proline transporter" BROAD [] xref: GO:0005297 is_a: CCO:F0001533 ! hydrogen:amino acid symporter activity is_a: CCO:F0002667 ! L-proline transmembrane transporter activity [Term] id: CCO:F0001544 name: proline:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in)." [TC:2.A.22.2.1] subset: gosubset_prok synonym: "sodium/proline symporter" EXACT [] xref: GO:0005298 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0002667 ! L-proline transmembrane transporter activity [Term] id: CCO:F0001545 name: high-affinity tryptophan transmembrane transporter activity namespace: molecular_function def: "Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid." [GOC:mtg_transport, ISBN:0815340729] synonym: "high-affinity tryptophan transporter activity" BROAD [] xref: GO:0005300 is_a: CCO:F0002670 ! L-tryptophan transmembrane transporter activity [Term] id: CCO:F0001546 name: L-tyrosine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-tyrosine permease activity" EXACT [] synonym: "L-tyrosine transporter activity" BROAD [] synonym: "valine/tyrosine/tryptophan permease activity" RELATED [] xref: GO:0005302 xref: GO:0015508 is_a: CCO:F0002650 ! aromatic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0001547 name: L-valine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "isoleucine/valine:sodium symporter activity" NARROW [] synonym: "L-valine transporter activity" BROAD [] synonym: "leucine/isoleucine/valine porter activity" NARROW [] synonym: "leucine/valine/isoleucine permease activity" NARROW [] synonym: "valine/tyrosine/tryptophan permease activity" NARROW [] xref: GO:0005304 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0001548 name: choline:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in)." [TC:2.A.22.3.5] synonym: "sodium/choline symporter" EXACT [] xref: GO:0005307 is_a: CCO:F0002691 ! choline transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001549 name: creatine transporter activity namespace: molecular_function def: "Enables the directed movement of creatine into, out of, within or between cells. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle." [GOC:ai] xref: GO:0005308 is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0001550 name: creatine:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in)." [TC:2.A.22.3.4] synonym: "sodium/chloride-dependent creatine transporter" BROAD [] xref: GO:0005309 is_a: CCO:F0001549 ! creatine transporter activity is_a: CCO:F0001560 ! neurotransmitter:sodium symporter activity [Term] id: CCO:F0001551 name: dicarboxylic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai] subset: gosubset_prok synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" NARROW [] synonym: "dicarboxylate carrier" NARROW [] synonym: "dicarboxylic acid permease activity" RELATED [] synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] xref: GO:0005310 xref: GO:0005312 xref: GO:0015365 is_a: CCO:F0006282 ! carboxylic acid transmembrane transporter activity [Term] id: CCO:F0001552 name: L-glutamate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "glutamate/aspartate porter activity" NARROW [] synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] synonym: "L-glutamate transporter activity" BROAD [] xref: GO:0005313 is_a: CCO:F0002649 ! acidic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0001553 name: high-affinity glutamate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + H+(out) = glutamate(in) + H+(in)." [TC:2.A.3.10.5] synonym: "high-affinity glutamate transporter activity" BROAD [] xref: GO:0005314 is_a: CCO:F0001552 ! L-glutamate transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001554 name: inorganic phosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] subset: gosubset_prok xref: GO:0005315 xref: GO:0005317 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001555 name: high affinity inorganic phosphate:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in)." [TC:2.A.20.2.2] synonym: "sodium/phosphate cotransporter" BROAD [] xref: GO:0005316 is_a: CCO:F0001613 ! sodium:phosphate symporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001556 name: lipid transporter activity namespace: molecular_function def: "Enables the directed movement of lipids into, out of, within or between cells." [GOC:ai] subset: gosubset_prok synonym: "apolipoprotein" RELATED [] synonym: "high-density lipoprotein" RELATED [] synonym: "lipophorin" NARROW [] synonym: "low-density lipoprotein" RELATED [] synonym: "very-low-density lipoprotein" RELATED [] xref: GO:0005319 xref: Reactome:7042 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0001557 name: long-chain fatty acid transporter activity namespace: molecular_function def: "Enables the directed movement of long-chain fatty acids into, out of, within or between cells. Long-chain fatty acids have a chain length of greater than 12 carbons." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "plasma membrane long-chain fatty acid transporter" NARROW [] xref: GO:0005324 is_a: CCO:F0002713 ! fatty acid transporter activity [Term] id: CCO:F0001558 name: peroxisomal fatty acyl CoA transporter activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + fatty acyl CoA(cis) = ADP + phosphate + fatty acyl CoA(trans). The transport of fatty acyl CoA into and out of peroxisomes." [EC:3.6.3.47] synonym: "ATP phosphohydrolase (fatty-acyl-CoA-transporting)" EXACT [EC:3.6.3.47] synonym: "fatty-acyl-CoA-transporting ATPase" BROAD [] xref: EC:3.6.3.47 xref: GO:0005325 xref: GO:0008562 is_a: CCO:F0001557 ! long-chain fatty acid transporter activity is_a: CCO:F0002970 ! fatty acyl CoA transporter activity [Term] id: CCO:F0001559 name: neurotransmitter transporter activity namespace: molecular_function def: "Enables the directed movement of a neurotransmitter into, out of, within or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: gosubset_prok xref: GO:0005326 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0001560 name: neurotransmitter:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in)." [TC:2.A.22.-.-] subset: gosubset_prok synonym: "sodium/neurotransmitter symporter" EXACT [] xref: GO:0005328 is_a: CCO:F0001559 ! neurotransmitter transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001561 name: dopamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of dopamine from one side of the membrane to the other. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." [GOC:ai] xref: GO:0005329 is_a: CCO:F0001958 ! monoamine transmembrane transporter activity is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0001562 name: dopamine:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) = dopamine(in) + Na+(in)." [TC:2.A.22.1.3] synonym: "sodium/dopamine symporter" EXACT [] xref: GO:0005330 is_a: CCO:F0001560 ! neurotransmitter:sodium symporter activity is_a: CCO:F0001561 ! dopamine transmembrane transporter activity [Term] id: CCO:F0001563 name: gamma-aminobutyric acid:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in)." [TC:2.A.22.3.2] comment: See also the molecular function term 'neurotransmitter:sodium symporter activity ; GO:0005328'. synonym: "4-aminobutanoate:sodium symporter activity" EXACT [] synonym: "4-aminobutyrate:sodium symporter activity" EXACT [] synonym: "betaine/GABA:sodium symporter activity" EXACT [] synonym: "GABA:sodium symporter activity" EXACT [] synonym: "sodium/chloride-dependent GABA transporter" RELATED [] xref: GO:0005332 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0002659 ! L-gamma-aminobutyric acid transmembrane transporter activity [Term] id: CCO:F0001564 name: norepinephrine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of norepinephrine from one side of the membrane to the other. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "levarterenol transporter" EXACT [] synonym: "noradrenaline transporter" EXACT [] xref: GO:0005333 is_a: CCO:F0001559 ! neurotransmitter transporter activity is_a: CCO:F0001958 ! monoamine transmembrane transporter activity [Term] id: CCO:F0001565 name: norephinephrine:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) = norepinephrine(in) + Na+(in)." [TC:2.A.22.1.2] synonym: "noradrenaline:sodium symporter activity" EXACT [] synonym: "sodium/norepinephrine symporter" EXACT [] xref: GO:0005334 is_a: CCO:F0001560 ! neurotransmitter:sodium symporter activity is_a: CCO:F0001564 ! norepinephrine transmembrane transporter activity [Term] id: CCO:F0001566 name: serotonin:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) = serotonin(in) + Na+(in)." [TC:2.A.22.1.1] synonym: "sodium/serotonin symporter" EXACT [] xref: GO:0005335 xref: GO:0005336 is_a: CCO:F0001560 ! neurotransmitter:sodium symporter activity [Term] id: CCO:F0001567 name: nucleoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "intracellular nucleoside transmembrane transporter activity" NARROW [] xref: GO:0005337 is_a: CCO:F0003026 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity [Term] id: CCO:F0001568 name: nucleotide-sugar transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a nucleotide-sugar from one side of the membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative." [GOC:ai, GOC:mtg_transport, ISBN:0815340729, PMID:15034926] xref: GO:0005338 xref: GO:0005339 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0001569 name: nucleotide-sulfate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nucleotide-sulfate from one side of a membrane to the other." [GOC:mtg_transport] synonym: "nucleotide-sulphate transporter activity" EXACT [] xref: GO:0005340 xref: GO:0005341 is_a: CCO:F0002594 ! sulfate transmembrane transporter activity [Term] id: CCO:F0001570 name: organic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005342 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0001571 name: organic acid:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in)." [TC:2.A.28.1.1] subset: gosubset_prok synonym: "sodium/chloride-dependent organic acid cotransporter" NARROW [] synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] xref: GO:0005343 is_a: CCO:F0001570 ! organic acid transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001572 name: oxygen transporter activity namespace: molecular_function def: "Enables the directed movement of oxygen into, out of, within or between cells." [GOC:ai] subset: gosubset_prok synonym: "globin" NARROW [] synonym: "hemerythrin" NARROW [] synonym: "hemocyanin" NARROW [] synonym: "oxygen-carrying" NARROW [] xref: GO:0005344 xref: GO:0015033 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0001573 name: purine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of purines, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005345 is_a: CCO:F0002677 ! nucleobase transmembrane transporter activity [Term] id: CCO:F0001574 name: purine ribonucleotide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other." [GOC:ai] xref: GO:0005346 is_a: CCO:F0002687 ! purine nucleotide transmembrane transporter activity [Term] id: CCO:F0001575 name: ATP transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other." [GOC:ai] xref: GO:0005347 xref: GO:0005348 is_a: CCO:F0000061 ! adenine nucleotide transmembrane transporter activity [Term] id: CCO:F0001576 name: pyrimidine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of pyrimidines, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0005350 is_a: CCO:F0002677 ! nucleobase transmembrane transporter activity [Term] id: CCO:F0001577 name: sugar:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in)." [TC:2.A.1.1.-] subset: gosubset_prok synonym: "cation/sugar symporter activity" BROAD [] synonym: "hydrogen:sugar symporter activity" EXACT [] synonym: "hydrogen:sugar transporter activity" BROAD [] synonym: "proton:sugar symporter activity" EXACT [] synonym: "sugar porter activity" RELATED [] synonym: "sugar transporter" BROAD [] synonym: "sugar:hydrogen ion symporter activity" EXACT [] xref: GO:0005351 xref: GO:0005403 is_a: CCO:F0001605 ! cation:sugar symporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0008062 ! sugar transmembrane transporter activity [Term] id: CCO:F0001578 name: alpha-glucoside:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose." [TC:2.A.1.1.11] synonym: "general alpha-glucoside transporter activity" BROAD [] synonym: "general alpha-glucoside:hydrogen symporter activity" EXACT [] synonym: "general alpha-glucoside:proton symporter activity" EXACT [] xref: GO:0005352 is_a: CCO:F0001605 ! cation:sugar symporter activity is_a: CCO:F0002628 ! alpha-glucoside transmembrane transporter activity [Term] id: CCO:F0001579 name: fructose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of fructose from one side of the membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "fructose permease activity" EXACT [] synonym: "fructose porter activity" EXACT [] xref: GO:0005353 xref: GO:0015585 xref: GO:0019192 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0001580 name: galactose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of galactose from one side of the membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "galactose/glucose (methylgalactoside) porter activity" NARROW [] xref: GO:0005354 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0001581 name: glucose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of the hexose monosaccharide glucose from one side of the membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "galactose/glucose (methylgalactoside) porter activity" NARROW [] synonym: "glucose permease activity" EXACT [] synonym: "lactose/glucose efflux transporter activity" NARROW [] xref: GO:0005355 xref: GO:0015579 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0001582 name: hydrogen:glucose symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] synonym: "hydrogen:glucose transporter activity" RELATED [] xref: GO:0005356 is_a: CCO:F0001581 ! glucose transmembrane transporter activity is_a: CCO:F0002404 ! hexose:hydrogen symporter activity [Term] id: CCO:F0001583 name: constitutive hydrogen:glucose symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constituitive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] synonym: "constitutive hydrogen/glucose transporter" EXACT [] synonym: "constitutive hydrogen:glucose transporter activity" RELATED [] xref: GO:0005357 is_a: CCO:F0001582 ! hydrogen:glucose symporter activity [Term] id: CCO:F0001584 name: high-affinity hydrogen:glucose symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constituitive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] synonym: "high-affinity hydrogen/glucose transporter" EXACT [] synonym: "high-affinity hydrogen:glucose transporter activity" RELATED [] xref: GO:0005358 is_a: CCO:F0001582 ! hydrogen:glucose symporter activity [Term] id: CCO:F0001585 name: low-affinity hydrogen:glucose symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] synonym: "low-affinity hydrogen/glucose transporter" EXACT [] synonym: "low-affinity hydrogen:glucose transporter activity" RELATED [] xref: GO:0005359 is_a: CCO:F0001582 ! hydrogen:glucose symporter activity [Term] id: CCO:F0001586 name: insulin-responsive hydrogen:glucose symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport] synonym: "insulin-responsive hydrogen:glucose transporter activity" RELATED [] synonym: "transepithelial hydrogen/glucose transporter" RELATED [] xref: GO:0005360 is_a: CCO:F0001582 ! hydrogen:glucose symporter activity [Term] id: CCO:F0001587 name: transepithelial hydrogen:glucose symporter activity namespace: molecular_function synonym: "transepithelial hydrogen/glucose transporter" EXACT [] synonym: "transepithelial hydrogen:glucose transporter activity" RELATED [] xref: GO:0005361 is_a: CCO:F0001582 ! hydrogen:glucose symporter activity [Term] id: CCO:F0001588 name: low-affinity glucose:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [TC:2.A.21.3.-] synonym: "low-affinity glucose-sodium cotransporter" BROAD [] xref: GO:0005362 is_a: CCO:F0001606 ! glucose:sodium symporter activity [Term] id: CCO:F0001589 name: maltose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of maltose from one side of the membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "maltose porter activity" EXACT [] xref: GO:0005363 xref: GO:0015581 is_a: CCO:F0002628 ! alpha-glucoside transmembrane transporter activity is_a: CCO:F0002631 ! disaccharide transmembrane transporter activity [Term] id: CCO:F0001590 name: maltose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in)." [TC:2.A.1.1.10] synonym: "hydrogen/maltose transporter" NARROW [] synonym: "maltose permease" BROAD [] synonym: "maltose:proton symporter" EXACT [] xref: GO:0005364 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0001589 ! maltose transmembrane transporter activity [Term] id: CCO:F0001591 name: myo-inositol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of myo-inositol from one side of the membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms." [GOC:ai] subset: gosubset_prok synonym: "vitamin Bh transporter activity" EXACT [] xref: GO:0005365 is_a: CCO:F0002643 ! polyol transmembrane transporter activity [Term] id: CCO:F0001592 name: myo-inositol:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in)." [TC:2.A.1.1.8] synonym: "hydrogen/myo-inositol transporter" BROAD [] synonym: "myo-inositol:proton symporter" EXACT [] xref: GO:0005366 is_a: CCO:F0001591 ! myo-inositol transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity [Term] id: CCO:F0001593 name: myo-inositol:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in)." [TC:2.A.21.4.-] synonym: "myo-inositol-sodium cotransporter" BROAD [] xref: GO:0005367 is_a: CCO:F0001591 ! myo-inositol transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001594 name: taurine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of taurine from one side of the membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats." [GOC:ai] subset: gosubset_prok xref: GO:0005368 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0001595 name: taurine:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in)." [TC:2.A.22.3.3] synonym: "sodium/chloride-dependent taurine transporter" BROAD [] xref: GO:0005369 is_a: CCO:F0001560 ! neurotransmitter:sodium symporter activity is_a: CCO:F0001571 ! organic acid:sodium symporter activity is_a: CCO:F0001594 ! taurine transmembrane transporter activity [Term] id: CCO:F0001596 name: tricarboxylate secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "citrate carrier" EXACT [] synonym: "tricarboxylate carrier activity" EXACT [] xref: GO:0005370 xref: GO:0005371 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001597 name: water transporter activity namespace: molecular_function def: "Enables the directed movement of water (H2O) into, out of, within or between cells." [GOC:ai] subset: gosubset_prok xref: GO:0005372 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0001598 name: copper ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of copper (Cu) ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "intracellular copper ion transporter" NARROW [] synonym: "plasma membrane copper transporter" NARROW [] xref: GO:0005375 xref: GO:0005378 xref: GO:0005379 xref: GO:0005380 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0001599 name: iron ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of iron (Fe) ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "iron transporter" EXACT [] synonym: "multicopper ferroxidase iron transport mediator activity" RELATED [] synonym: "transmembrane iron ion permease activity" EXACT [] synonym: "transmembrane iron permease activity" EXACT [] synonym: "zinc, iron permease activity" RELATED [] xref: GO:0005381 xref: GO:0005382 xref: GO:0016033 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0001600 name: manganese ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other." [GOC:df] subset: gosubset_prok xref: GO:0005384 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0001601 name: zinc ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of zinc (Zn) ions from one side of a membrane to the other." [GOC:df] subset: gosubset_prok synonym: "cobalt, zinc uptake permease activity" NARROW [] synonym: "zinc, cadmium uptake permease activity" NARROW [] synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" NARROW [] synonym: "zinc, iron permease activity" NARROW [] xref: GO:0005385 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0001602 name: calcium-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans)." [EC:3.6.3.8] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (Ca2+-transporting)" EXACT [EC:3.6.3.8] synonym: "Ca(2+)-transporting ATPase activity" EXACT [EC:3.6.3.8] synonym: "Ca2+-pumping ATPase activity" EXACT [EC:3.6.3.8] synonym: "Ca2+-transporting ATPase activity" EXACT [EC:3.6.3.8] synonym: "calcium ABC transporter" NARROW [] synonym: "calcium efflux ATPase" NARROW [] synonym: "calcium pump" BROAD [] synonym: "calcium transporting ATPase activity" EXACT [] synonym: "calcium-translocating P-type ATPase activity" NARROW [EC:3.6.3.8] synonym: "plasma membrane Ca-ATPase" NARROW [EC:3.6.3.8] synonym: "sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [EC:3.6.3.8] synonym: "sarcoplasmic reticulum ATPase" NARROW [] xref: EC:3.6.3.8 xref: GO:0005388 xref: MetaCyc:3.6.3.8-RXN is_a: CCO:F0002565 ! calcium ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism is_a: CCO:F0004186 ! cation-transporting ATPase activity [Term] id: CCO:F0001603 name: sodium:potassium-exchanging ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in)." [EC:3.6.3.9] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "(Na+ + K+)-activated ATPase activity" EXACT [EC:3.6.3.9] synonym: "(Na+ + K+)-ATPase activity" EXACT [EC:3.6.3.9] synonym: "ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [EC:3.6.3.9] synonym: "Na(+)/K(+)-ATPase activity" EXACT [EC:3.6.3.9] synonym: "Na(+)/K(+)-exchanging ATPase activity" EXACT [EC:3.6.3.9] synonym: "Na+,K+ pump" RELATED [EC:3.6.3.9] synonym: "Na+,K+-ATPase activity" EXACT [EC:3.6.3.9] synonym: "Na+/K+-ATPase activity" EXACT [EC:3.6.3.9] synonym: "Na+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.9] synonym: "na+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.9] synonym: "Na,K-activated ATPase activity" EXACT [EC:3.6.3.9] synonym: "Na,K-pump" RELATED [EC:3.6.3.9] synonym: "sodium pump" BROAD [] synonym: "sodium/potassium-exchanging ATPase activity" EXACT [] synonym: "sodium/potassium-transporting ATPase activity" EXACT [EC:3.6.3.9] synonym: "sodium:potassium exchanging ATPase activity" EXACT [] xref: EC:3.6.3.9 xref: GO:0005391 xref: MetaCyc:3.6.3.9-RXN is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0001604 name: eye pigment precursor transporter activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out)." [TC:3.A.1.204.1] xref: GO:0005395 is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0001605 name: cation:sugar symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in)." [GOC:ai] subset: gosubset_prok synonym: "cation/sugar symporter" EXACT [] synonym: "sugar:cation symporter activity" EXACT [] xref: GO:0005402 is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0001606 name: glucose:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in)." [TC:2.A.21.3.-] synonym: "sodium/glucose symporter" EXACT [] xref: GO:0005412 is_a: CCO:F0001581 ! glucose transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001607 name: nucleoside:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in)." [GOC:ai] subset: gosubset_prok synonym: "nucleoside-sodium cotransporter" BROAD [] synonym: "sodium-dependent nucleoside transporter" BROAD [] xref: GO:0005415 xref: GO:0008522 is_a: CCO:F0001567 ! nucleoside transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001608 name: cation:amino acid symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in)." [GOC:ai] subset: gosubset_prok synonym: "cation/amino acid symporter" EXACT [] xref: GO:0005416 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0001609 name: proton-dependent oligopeptide secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement." [GOC:mtg_transport, OMIM:600544] subset: gosubset_prok synonym: "hydrogen/oligopeptide symporter" RELATED [] synonym: "proton-dependent oligopeptide transporter activity" EXACT [] xref: GO:0005427 is_a: CCO:F0002767 ! secondary active oligopeptide transmembrane transporter activity [Term] id: CCO:F0001610 name: chromaffin granule amine transmembrane transporter activity namespace: molecular_function xref: GO:0005429 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0001611 name: synaptic vesicle amine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of amines across synaptic vesicle membranes." [GOC:ai] xref: GO:0005430 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0001612 name: calcium:sodium antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in)." [UniProtKB:P70414] subset: gosubset_prok synonym: "mitochondrial sodium/calcium ion exchange" RELATED [] synonym: "sodium/calcium exchanger" EXACT [] synonym: "sodium:calcium exchange" RELATED [] xref: GO:0005432 is_a: CCO:F0002795 ! calcium:cation antiporter activity [Term] id: CCO:F0001613 name: sodium:phosphate symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in)." [GOC:ai] subset: gosubset_prok synonym: "sodium/phosphate symporter" EXACT [] xref: GO:0005436 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0001614 name: monovalent cation:proton antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out)." [GOC:ai] subset: gosubset_prok xref: GO:0005451 is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity is_a: CCO:F0002748 ! solute:hydrogen antiporter activity is_a: CCO:F0002886 ! cation:cation antiporter activity [Term] id: CCO:F0001615 name: inorganic anion exchanger activity namespace: molecular_function xref: GO:0005452 is_a: CCO:F0002805 ! anion exchanger activity [Term] id: CCO:F0001616 name: CMP-sialic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a CMP-sialic acid from one side of the membrane to the other. CMP-sialic acid is a substance composed of sialic acid in glycosidic linkage with cytidine monophosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005456 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001617 name: GDP-fucose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a GDP-fucose from one side of the membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005457 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001618 name: GDP-mannose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a GDP-mannose from one side of the membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005458 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001619 name: UDP-galactose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a UDP-galactose from one side of the membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005459 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001620 name: UDP-glucose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a UDP-glucose from one side of the membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005460 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001621 name: UDP-glucuronic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a UDP-glucuronic acid from one side of the membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005461 xref: Reactome:15054 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001622 name: UDP-N-acetylglucosamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a UDP-N-acetylglucosamine from one side of the membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005462 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001623 name: UDP-N-acetylgalactosamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a N-acetylgalactosamine from one side of the membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0005463 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001624 name: UDP-xylose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of UDP-xylose from one side of the membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate." [GOC:ai] xref: GO:0005464 is_a: CCO:F0002642 ! pyrimidine nucleotide sugar transmembrane transporter activity [Term] id: CCO:F0001625 name: succinate:fumarate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out)." [TC:2.A.29.13.1] xref: GO:0005469 is_a: CCO:F0002615 ! fumarate transmembrane transporter activity is_a: CCO:F0002618 ! succinate transmembrane transporter activity is_a: CCO:F0002746 ! antiporter activity [Term] id: CCO:F0001626 name: ATP:ADP antiporter activity namespace: molecular_function def: "Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out)." [TC:2.A.29.1.1] subset: gosubset_prok synonym: "adenine nucleotide translocase" EXACT [] synonym: "ADP/ATP translocase" EXACT [] synonym: "ATP/ADP exchange" EXACT [] synonym: "ATP/ADP exchanger" EXACT [] xref: GO:0005349 xref: GO:0005471 is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0001627 name: FAD carrier activity namespace: molecular_function synonym: "flavin adenine dinucleotide carrier activity" EXACT [] synonym: "flavin-adenine dinucleotide carrier activity" EXACT [] xref: GO:0005472 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001628 name: carnitine:acyl carnitine antiporter activity namespace: molecular_function def: "Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial)." [PMID:9032458] synonym: "carnitine/acyl carnitine carrier activity" EXACT [] synonym: "carnitine:acyl carnitine carrier activity" EXACT [] synonym: "fatty acyl carnitine carrier" EXACT [] xref: GO:0005476 is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0001629 name: pyruvate secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] synonym: "pyruvate carrier activity" RELATED [] xref: GO:0005477 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0008022 ! pyruvate transmembrane transporter activity [Term] id: CCO:F0001630 name: soluble NSF attachment protein activity namespace: molecular_function def: "Interacting selectively with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex." [GOC:mah, PMID:14570579, PMID:15556857] synonym: "SNAP" EXACT [] xref: GO:0005483 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001631 name: SNAP receptor activity namespace: molecular_function def: "Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion." [GOC:mah, PMID:14570579] synonym: "Q-SNARE activity" NARROW [] synonym: "R-SNARE activity" NARROW [] synonym: "SNAP-25" NARROW [] synonym: "SNARE" EXACT [] synonym: "t-SNARE activity" NARROW [] synonym: "v-SNARE activity" NARROW [] xref: GO:0005484 xref: GO:0005485 xref: GO:0005486 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001632 name: nucleocytoplasmic transporter activity namespace: molecular_function def: "Enables the directed movement of substances between the nucleus and the cytoplasm of a cell." [GOC:ai] xref: GO:0005487 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0001633 name: binding namespace: molecular_function def: "The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." [GOC:ceb, GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children. subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: gosubset_prok synonym: "ligand" NARROW [] xref: GO:0005488 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0001634 name: steroid binding namespace: molecular_function def: "Interacting selectively with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0005496 is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0001635 name: androgen binding namespace: molecular_function def: "Interacting selectively with any androgen, male sex hormones." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0005497 is_a: CCO:F0001634 ! steroid binding is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0001636 name: sterol carrier activity namespace: molecular_function subset: gosubset_prok xref: GO:0005498 is_a: CCO:F0005049 ! sterol binding [Term] id: CCO:F0001637 name: vitamin D binding namespace: molecular_function def: "Interacting selectively with vitamin D, a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the human bloodstream. Vitamin D is also known as calciferol and five different forms are known, including ergocalciferol and cholecalciferol." [GOC:ai] synonym: "calciferol binding" EXACT [] synonym: "cholecalciferol binding" NARROW [] synonym: "ergocalciferol binding" NARROW [] xref: GO:0005499 is_a: CCO:F0001634 ! steroid binding is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0001638 name: juvenile hormone binding namespace: molecular_function def: "Interacting selectively with juvenile hormone, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005500 is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0001639 name: retinoid binding namespace: molecular_function def: "Interacting selectively with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005501 is_a: CCO:F0004189 ! isoprenoid binding [Term] id: CCO:F0001640 name: 11-cis retinal binding namespace: molecular_function def: "Interacting selectively with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A." [http://cancerweb.ncl.ac.uk/] synonym: "11-cis retinaldehyde binding" EXACT [] synonym: "vitamin A binding" BROAD [] xref: GO:0005502 is_a: CCO:F0003468 ! retinal binding [Term] id: CCO:F0001641 name: all-trans retinal binding namespace: molecular_function def: "Interacting selectively with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A." [http://cancerweb.ncl.ac.uk/] synonym: "all-trans retinaldehyde binding" EXACT [] synonym: "trans retinal binding" EXACT [] synonym: "visual yellow binding" EXACT [] synonym: "vitamin A binding" BROAD [] synonym: "xanthopsin" RELATED [] xref: GO:0005503 is_a: CCO:F0003468 ! retinal binding [Term] id: CCO:F0001642 name: fatty acid binding namespace: molecular_function def: "Interacting selectively with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005504 is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0001643 name: iron ion binding namespace: molecular_function def: "Interacting selectively with iron (Fe) ions." [GOC:ai] subset: gosubset_prok synonym: "iron binding" EXACT [] xref: GO:0005506 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0001644 name: copper ion binding namespace: molecular_function def: "Interacting selectively with copper (Cu) ions." [GOC:ai] subset: gosubset_prok synonym: "copper binding" EXACT [] synonym: "copper/cadmium binding" BROAD [] xref: GO:0005507 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0001645 name: calcium ion binding namespace: molecular_function def: "Interacting selectively with calcium ions (Ca2+)." [GOC:ai] subset: goslim_generic subset: gosubset_prok synonym: "calcium ion storage activity" RELATED [] xref: GO:0005509 is_a: CCO:F0005808 ! cation binding is_a: CCO:F0006257 ! metal ion binding [Term] id: CCO:F0001646 name: protein binding namespace: molecular_function def: "Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "alpha-2 macroglobulin receptor-associated protein activity" RELATED [] synonym: "protein amino acid binding" EXACT [] synonym: "protein degradation tagging activity" RELATED [] synonym: "protein tagging activity" RELATED [] xref: GO:0005515 xref: GO:0045308 xref: Reactome:6125 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0001647 name: calmodulin binding namespace: molecular_function def: "Interacting selectively with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states." [GOC:krc] subset: gosubset_prok xref: GO:0005516 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001648 name: calmodulin inhibitor activity namespace: molecular_function xref: GO:0005517 is_a: CCO:F0001647 ! calmodulin binding [Term] id: CCO:F0001649 name: collagen binding namespace: molecular_function def: "Interacting selectively with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005518 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001650 name: cytoskeletal regulatory protein binding namespace: molecular_function def: "Interacting selectively with any protein involved in modulating the reorganization of the cytoskeleton." [GOC:go_curators, PMID:15163540] xref: GO:0005519 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0001651 name: insulin-like growth factor binding namespace: molecular_function def: "Interacting selectively with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "IGF binding" EXACT [] xref: GO:0005520 is_a: CCO:F0004188 ! growth factor binding [Term] id: CCO:F0001652 name: lamin binding namespace: molecular_function def: "Interacting selectively with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "lamin/chromatin binding" BROAD [] xref: GO:0005521 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001653 name: profilin binding namespace: molecular_function def: "Interacting selectively with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0005522 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001654 name: tropomyosin binding namespace: molecular_function def: "Interacting selectively with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle." [http://cancerweb.ncl.ac.uk/] xref: GO:0005523 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0001655 name: ATP binding namespace: molecular_function def: "Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005524 is_a: CCO:F0005022 ! adenyl ribonucleotide binding [Term] id: CCO:F0001656 name: GTP binding namespace: molecular_function def: "Interacting selectively with GTP, guanosine triphosphate." [GOC:ai] subset: gosubset_prok xref: GO:0005525 is_a: CCO:F0005024 ! guanyl ribonucleotide binding [Term] id: CCO:F0001657 name: macrolide binding namespace: molecular_function def: "Interacting selectively with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005527 is_a: CCO:F0001746 ! drug binding [Term] id: CCO:F0001658 name: FK506 binding namespace: molecular_function def: "Interacting selectively with the immunosuppressant FK506." [GOC:jl] synonym: "FK506-sensitive peptidyl-prolyl cis-trans isomerase" RELATED [] xref: GO:0005528 is_a: CCO:F0001657 ! macrolide binding [Term] id: CCO:F0001659 name: sugar binding namespace: molecular_function def: "Interacting selectively with any mono-, di- or trisaccharide carbohydrate." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005529 is_a: CCO:F0004356 ! carbohydrate binding [Term] id: CCO:F0001660 name: galactose binding namespace: molecular_function def: "Interacting selectively with galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "galactose binding lectin" RELATED [] xref: GO:0005534 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0001661 name: glucose binding namespace: molecular_function def: "Interacting selectively with the D- and L-enantiomers of glucose." [GOC:jl] subset: gosubset_prok xref: GO:0005536 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0001662 name: mannose binding namespace: molecular_function def: "Interacting selectively with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans." [GOC:jl, ISBN:0192800981] subset: gosubset_prok synonym: "mannose binding lectin" RELATED [] xref: GO:0005537 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0001663 name: glycosaminoglycan binding namespace: molecular_function def: "Interacting selectively with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005539 is_a: CCO:F0004357 ! polysaccharide binding [Term] id: CCO:F0001664 name: hyaluronic acid binding namespace: molecular_function def: "Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine." [GOC:jl, http://cancerweb.ncl.ac.uk/] synonym: "hyaluronan binding" EXACT [] xref: GO:0005540 is_a: CCO:F0001663 ! glycosaminoglycan binding [Term] id: CCO:F0001665 name: folic acid binding namespace: molecular_function def: "Interacting selectively with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "folate binding" EXACT [] synonym: "vitamin B9 binding" EXACT [] synonym: "vitamin M binding" EXACT [] xref: GO:0005542 is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0001666 name: phospholipid binding namespace: molecular_function def: "Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005543 is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0001667 name: calcium-dependent phospholipid binding namespace: molecular_function def: "Interacting selectively with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium." [GOC:jl] subset: gosubset_prok xref: GO:0005544 is_a: CCO:F0001666 ! phospholipid binding [Term] id: CCO:F0001668 name: phosphatidylinositol binding namespace: molecular_function def: "Interacting selectively with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0005545 is_a: CCO:F0005562 ! phosphoinositide binding [Term] id: CCO:F0001669 name: phosphatidylinositol-4,5-bisphosphate binding namespace: molecular_function def: "Interacting selectively with phosphatidylinositol-4,5-bisphosphate, a diphosphorylated derivative of phosphatidylinositol." [GOC:bf, GOC:jl] xref: GO:0005546 is_a: CCO:F0005562 ! phosphoinositide binding [Term] id: CCO:F0001670 name: phosphatidylinositol-3,4,5-triphosphate binding namespace: molecular_function def: "Interacting selectively with phosphatidylinositol-3,4,5-triphosphate, the triphosphorylated derivative of phosphatidylinositol." [GOC:bf, GOC:jl] xref: GO:0005547 is_a: CCO:F0005562 ! phosphoinositide binding [Term] id: CCO:F0001671 name: phospholipid transporter activity namespace: molecular_function def: "Enables the directed movement of phospholipids into, out of, within or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0005548 xref: GO:0008497 is_a: CCO:F0001556 ! lipid transporter activity [Term] id: CCO:F0001672 name: odorant binding namespace: molecular_function def: "Interacting selectively with an odorant, any substance capable of stimulating the sense of smell." [GOC:jl, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: goslim_pir subset: gosubset_prok xref: GO:0005549 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0001673 name: pheromone binding namespace: molecular_function def: "Interacting selectively with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." [GOC:ai] xref: GO:0005550 is_a: CCO:F0001672 ! odorant binding [Term] id: CCO:F0001674 name: chemokine activity namespace: molecular_function def: "The function of a family of chemotactic pro-inflammatory activation-inducible cytokines acting primarily upon hemopoietic cells in immunoregulatory processes; all chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation." [http://www.copewithcytokines.de/cope.cgi?001252] comment: See also the molecular function term 'cytokine activity ; GO:0005125'. xref: GO:0008009 is_a: CCO:F0001427 ! cytokine activity is_a: CCO:F0005665 ! chemokine receptor binding [Term] id: CCO:F0001675 name: structural constituent of chitin-based larval cuticle namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva." [GOC:mah, GOC:mtg_sensu] synonym: "structural constituent of larval cuticle (sensu Insecta)" EXACT [] xref: GO:0008010 is_a: CCO:F0001490 ! structural constituent of chitin-based cuticle [Term] id: CCO:F0001676 name: structural constituent of pupal chitin-based cuticle namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an pupa." [GOC:mah, GOC:mtg_sensu] synonym: "structural constituent of pupal cuticle (sensu Insecta)" EXACT [] xref: GO:0008011 is_a: CCO:F0001490 ! structural constituent of chitin-based cuticle [Term] id: CCO:F0001677 name: structural constituent of adult chitin-based cuticle namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism." [GOC:mah, GOC:mtg_sensu] synonym: "structural constituent of adult cuticle (sensu Insecta)" EXACT [] xref: GO:0008012 is_a: CCO:F0001490 ! structural constituent of chitin-based cuticle [Term] id: CCO:F0001678 name: beta-catenin binding namespace: molecular_function def: "Interacting selectively with the beta subunit of the catenin complex." [GOC:bf] xref: GO:0008013 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001679 name: microtubule binding namespace: molecular_function def: "Interacting selectively with microtubules, filaments composed of tubulin monomers." [GOC:krc] synonym: "microtubule severing activity" RELATED [] synonym: "microtubule/chromatin interaction" RELATED [] xref: GO:0008017 is_a: CCO:F0002987 ! tubulin binding [Term] id: CCO:F0001680 name: G-protein coupled photoreceptor activity namespace: molecular_function def: "A G-protein coupled receptor that responds to incidental electromagnetic radiation, particularly visible light." [GOC:dph, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "G protein coupled photoreceptor activity" EXACT [] synonym: "G-protein-coupled photoreceptor activity" EXACT [] xref: GO:0004975 xref: GO:0008020 is_a: CCO:F0000141 ! rhodopsin-like receptor activity is_a: CCO:F0002410 ! photoreceptor activity [Term] id: CCO:F0001681 name: protein C-terminus binding namespace: molecular_function def: "Interacting selectively with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "C-terminal binding" EXACT [] xref: GO:0008022 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001682 name: ATP-dependent helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the unwinding of a DNA or RNA helix." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok xref: GO:0008026 is_a: CCO:F0000803 ! helicase activity is_a: CCO:F0005696 ! ATPase activity, coupled [Term] id: CCO:F0001683 name: monocarboxylic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai] subset: gosubset_prok synonym: "monocarboxylate carrier" NARROW [] synonym: "prostaglandin/thromboxane transporter activity" NARROW [] xref: GO:0008028 xref: GO:0008505 is_a: CCO:F0006282 ! carboxylic acid transmembrane transporter activity [Term] id: CCO:F0001684 name: pentraxin receptor activity namespace: molecular_function def: "Combining with a pentraxin to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP). synonym: "pentaxin receptor" EXACT [] xref: GO:0008029 is_a: CCO:F0000221 ! opsonin receptor activity is_a: CCO:F0000238 ! pentraxin binding [Term] id: CCO:F0001685 name: neuronal pentraxin receptor activity namespace: molecular_function synonym: "neuronal pentaxin receptor" EXACT [] xref: GO:0008030 is_a: CCO:F0001684 ! pentraxin receptor activity [Term] id: CCO:F0001686 name: eclosion hormone activity namespace: molecular_function xref: GO:0008031 is_a: CCO:F0001481 ! neuropeptide hormone activity [Term] id: CCO:F0001687 name: lipoprotein binding namespace: molecular_function def: "Interacting selectively with any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0008034 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001688 name: high-density lipoprotein binding namespace: molecular_function def: "Interacting selectively with high-density lipoprotein: one of the classes of lipoproteins found in blood plasma in many animals (data normally relate to humans)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0008035 is_a: CCO:F0001687 ! lipoprotein binding [Term] id: CCO:F0001689 name: diuretic hormone receptor activity namespace: molecular_function def: "Combining with a diuretic hormone to initiate a change in cell activity." [GOC:ai] xref: GO:0008036 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0001690 name: axon guidance receptor activity namespace: molecular_function xref: GO:0008046 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001691 name: enzyme activator activity namespace: molecular_function def: "Increases the activity of an enzyme." [GOC:mah] subset: gosubset_prok xref: GO:0008047 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0001692 name: calcium sensitive guanylate cyclase activator activity namespace: molecular_function xref: GO:0008048 is_a: CCO:F0004360 ! guanylate cyclase activator activity [Term] id: CCO:F0001693 name: ARF GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by the GTPase ARF." [GOC:mah] xref: GO:0008060 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0001401 ! GTPase activator activity [Term] id: CCO:F0001694 name: chitin binding namespace: molecular_function def: "Interacting selectively with chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0008061 is_a: CCO:F0004357 ! polysaccharide binding [Term] id: CCO:F0001695 name: glutamate receptor activity namespace: molecular_function def: "Combining with glutamate to initiate a change in cell activity." [GOC:ai] subset: gosubset_prok xref: GO:0008066 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001696 name: metabotropic glutamate, GABA-B-like receptor activity namespace: molecular_function def: "A G-protein coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor." [GOC:dph, GOC:tb, IUPHAR_GPCR:1285] synonym: "class C G protein coupled receptor" BROAD [] synonym: "class C G-protein coupled receptor" BROAD [] synonym: "class C GPCR" BROAD [] synonym: "class C orphan receptor activity" EXACT [] xref: GO:0001643 xref: GO:0001645 xref: GO:0008067 is_a: CCO:F0001272 ! G-protein coupled receptor activity is_a: CCO:F0001695 ! glutamate receptor activity [Term] id: CCO:F0001697 name: extracellular-glutamate-gated chloride channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'. xref: GO:0008068 is_a: CCO:F0001508 ! extracellular-glutamate-gated ion channel activity is_a: CCO:F0001522 ! chloride channel activity [Term] id: CCO:F0001698 name: ornithine decarboxylase inhibitor activity namespace: molecular_function def: "The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase." [GOC:jl] xref: GO:0008073 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0005777 ! ornithine decarboxylase regulator activity [Term] id: CCO:F0001699 name: translation termination factor activity namespace: molecular_function def: "Functions in the termination of translation." [GOC:ma] subset: gosubset_prok xref: GO:0008079 is_a: CCO:F0001739 ! translation factor activity, nucleic acid binding [Term] id: CCO:F0001700 name: N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0008080 is_a: CCO:F0003130 ! acetyltransferase activity is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0001701 name: phosphoric diester hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group." [http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "endonuclease VIII activity" RELATED [] synonym: "phosphodiesterase" NARROW [] xref: EC:3.1.4 xref: GO:0008081 xref: GO:0016792 is_a: CCO:F0005685 ! phosphoric ester hydrolase activity [Term] id: CCO:F0001702 name: growth factor activity namespace: molecular_function def: "The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation." [ISBN:0815316194] xref: GO:0008083 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0001703 name: imaginal disc growth factor activity namespace: molecular_function xref: GO:0008084 is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0001704 name: light-activated voltage-gated calcium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light." [GOC:mtg_transport] synonym: "light-activated voltage gated calcium channel activity" EXACT [] synonym: "light-activated voltage-dependent calcium channel activity" EXACT [] xref: GO:0008086 is_a: CCO:F0001513 ! voltage-gated calcium channel activity is_a: CCO:F0002501 ! light-activated channel activity [Term] id: CCO:F0001705 name: cytoskeletal protein binding namespace: molecular_function def: "Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)." [GOC:mah] subset: goslim_generic subset: gosubset_prok xref: GO:0008092 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001706 name: cytoskeletal adaptor activity namespace: molecular_function def: "The binding activity of a molecule that brings together a cytoskeletal molecule and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT] xref: GO:0008093 is_a: CCO:F0001705 ! cytoskeletal protein binding is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0001707 name: DNA-dependent ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single- or double-stranded DNA; drives another reaction." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "adenosinetriphosphatase (DNA-dependent)" EXACT [] synonym: "DNA dependent ATPase activity" EXACT [] synonym: "DNA-dependent adenosinetriphosphatase activity" EXACT [] xref: GO:0004011 xref: GO:0008094 is_a: CCO:F0005696 ! ATPase activity, coupled [Term] id: CCO:F0001708 name: inositol-1,4,5-triphosphate receptor activity namespace: molecular_function def: "Combining with inositol-1,4,5-triphosphate to initiate a change in cell activity." [GOC:ai] synonym: "IP3 receptor activity" EXACT [] xref: GO:0008095 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0001709 name: juvenile hormone epoxide hydrolase activity namespace: molecular_function xref: EC:3.3.2.- xref: GO:0008096 is_a: CCO:F0000723 ! epoxide hydrolase activity [Term] id: CCO:F0001710 name: 5S rRNA binding namespace: molecular_function def: "Interacting selectively with 5S ribosomal RNA, the smallest RNA constituent of a ribosome." [GOC:jl, ISBN:0321000382] subset: gosubset_prok xref: GO:0008097 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0001711 name: 5S rRNA primary transcript binding namespace: molecular_function def: "Interacting selectively with the unprocessed 5S ribosomal RNA transcript." [GOC:jl] xref: GO:0008098 is_a: CCO:F0001710 ! 5S rRNA binding [Term] id: CCO:F0001712 name: alcohol dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+." [EC:1.1.1.2] subset: gosubset_prok synonym: "aldehyde reductase (NADPH) activity" EXACT [EC:1.1.1.2] synonym: "aldehyde reductase (NADPH2)" EXACT [] synonym: "NADP-aldehyde reductase activity" EXACT [] xref: EC:1.1.1.2 xref: GO:0008106 xref: MetaCyc:ALCOHOL-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0000511 ! aldo-keto reductase activity [Term] id: CCO:F0001713 name: galactoside 2-alpha-L-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R." [EC:2.4.1.69] subset: gosubset_prok synonym: "alpha(1,2)-L-fucosyltransferase activity" EXACT [] synonym: "alpha-(1->2)-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "alpha-2-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "alpha-2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "beta-galactoside alpha-1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "beta-galactoside alpha1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "blood group H alpha-2-fucosyltransferase activity" NARROW [EC:2.4.1.69] synonym: "blood-group substance H-dependent fucosyltransferase activity" NARROW [EC:2.4.1.69] synonym: "galactoside 2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "GDP fucose-lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "GDP-L-fucose:lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphospho-L-fucose-lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphosphofucose-galactoside 2-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-glucosylceramide alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "guanosine diphosphofucose-lactose fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase activity" NARROW [EC:2.4.1.69] synonym: "H-gene-encoded beta-galactoside alpha1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] synonym: "secretor-type beta-galactoside alpha-1->2 fucosyltransferase activity" NARROW [EC:2.4.1.69] synonym: "secretor-type beta-galactoside alpha1->2 fucosyltransferase activity" EXACT [EC:2.4.1.69] xref: EC:2.4.1.69 xref: GO:0008107 xref: MetaCyc:GALACTOSIDE-2-L-FUCOSYLTRANSFERASE-RXN is_a: CCO:F0004632 ! alpha(1,2)-fucosyltransferase activity [Term] id: CCO:F0001714 name: UDP-glucose:hexose-1-phosphate uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose." [EC:2.7.7.12] subset: gosubset_prok synonym: "Gal-1-P uridylyltransferase activity" BROAD [EC:2.7.7.12] synonym: "galactose-1-phosphate uridylyltransferase activity" BROAD [EC:2.7.7.12] synonym: "hexose 1-phosphate uridyltransferase activity" EXACT [EC:2.7.7.12] synonym: "hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] synonym: "UDP-glucose-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] synonym: "UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] synonym: "UDPglucose-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] synonym: "UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.12] synonym: "uridyl transferase activity" BROAD [EC:2.7.7.12] synonym: "uridyltransferase activity" EXACT [EC:2.7.7.12] synonym: "uridylyl removing enzyme activity" BROAD [EC:2.7.7.12] xref: EC:2.7.7.12 xref: GO:0008108 xref: MetaCyc:GALACTURIDYLYLTRANS-RXN xref: Reactome:22869 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0001715 name: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.150] synonym: "galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.150] synonym: "N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.150] synonym: "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase activity" EXACT [EC:2.4.1.150] synonym: "UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.150] synonym: "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.150] synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase" BROAD [EC:2.4.1.150] xref: EC:2.4.1.150 xref: GO:0008109 xref: MetaCyc:2.4.1.150-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0001716 name: histidine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-histidine + 2-oxoglutarate = imidazol-5-yl-pyruvate + L-glutamate." [EC:2.6.1.38] synonym: "histidine aminotransferase activity" EXACT [] synonym: "histidine-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.38] synonym: "L-histidine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.38] xref: EC:2.6.1.38 xref: GO:0008110 xref: MetaCyc:HISTTRANSAM-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0001717 name: alpha-methylacyl-CoA racemase activity namespace: molecular_function def: "Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA." [EC:5.1.99.4] subset: gosubset_prok synonym: "2-methylacyl-CoA 2-epimerase activity" EXACT [EC:5.1.99.4] xref: EC:5.1.99.4 xref: GO:0008111 xref: MetaCyc:5.1.99.4-RXN is_a: CCO:F0003417 ! racemase and epimerase activity [Term] id: CCO:F0001718 name: nicotinamide N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide." [EC:2.1.1.1] subset: gosubset_prok synonym: "nicotinamide methyltransferase activity" EXACT [EC:2.1.1.1] synonym: "S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity" EXACT [EC:2.1.1.1] xref: EC:2.1.1.1 xref: GO:0008112 xref: MetaCyc:NICOTINAMIDE-N-METHYLTRANSFERASE-RXN xref: Reactome:22892 is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001719 name: peptide-methionine-(S)-S-oxide reductase activity namespace: molecular_function def: "Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin." [EC:1.8.4.11, PMID:11169920] subset: gosubset_prok synonym: "methionine S-oxide reductase (S-form oxidizing) activity" EXACT [EC:1.8.4.11] synonym: "methionine S-oxide reductase activity" BROAD [EC:1.8.4.11] synonym: "methionine sulfoxide (protein) reductase activity" EXACT [] synonym: "methionine sulfoxide reductase A activity" EXACT [EC:1.8.4.11] synonym: "methionine sulfoxide reductase activity" BROAD [EC:1.8.4.11] synonym: "methionine sulphoxide reductase A activity" EXACT [EC:1.8.4.11] synonym: "MsrA" RELATED [EC:1.8.4.11] synonym: "peptide Met(O) reductase activity" EXACT [EC:1.8.4.11] synonym: "peptide methionine sulfoxide reductase activity" EXACT [EC:1.8.4.11] synonym: "peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity" EXACT [EC:1.8.4.11] synonym: "protein-methionine-S-oxide reductase activity" EXACT [EC:1.8.4.11] xref: EC:1.8.4.11 xref: GO:0008113 xref: GO:0033742 xref: MetaCyc:PROTEIN-METHIONINE-S-OXIDE-REDUCTASE-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0001720 name: phosphogluconate 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH." [EC:1.1.1.43] synonym: "2-keto-6-phosphogluconate reductase activity" EXACT [EC:1.1.1.43] synonym: "6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.43] synonym: "6-phosphogluconate 2-dehydrogenase activity" EXACT [] synonym: "6-phosphogluconate dehydrogenase (NAD)" EXACT [EC:1.1.1.43] synonym: "6-phosphogluconic dehydrogenase activity" BROAD [EC:1.1.1.43] synonym: "gluconate 6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.43] synonym: "phosphogluconate dehydrogenase activity" EXACT [EC:1.1.1.43] xref: EC:1.1.1.43 xref: GO:0008114 xref: MetaCyc:1.1.1.43-RXN xref: Reactome:22895 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001721 name: sarcosine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: sarcosine + H2O + O2 = glycine + formaldehyde + H2O2." [EC:1.5.3.1] subset: gosubset_prok synonym: "sarcosine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.1] xref: EC:1.5.3.1 xref: GO:0008115 xref: MetaCyc:SARCOX-RXN is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0001722 name: prostaglandin-I synthase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate." [EC:5.3.99.4] synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity" EXACT [EC:5.3.99.4] synonym: "cytochrome P450 CYP8A1" NARROW [] synonym: "PGI(2) synthase activity" EXACT [EC:5.3.99.4] synonym: "PGI(2) synthetase activity" EXACT [EC:5.3.99.4] synonym: "PGI2 synthase activity" EXACT [EC:5.3.99.4] synonym: "PGI2 synthetase activity" EXACT [EC:5.3.99.4] synonym: "prostacyclin synthase activity" EXACT [EC:5.3.99.4] synonym: "prostacycline synthetase activity" EXACT [EC:5.3.99.4] synonym: "prostagladin I2 synthetase activity" EXACT [EC:5.3.99.4] xref: EC:5.3.99.4 xref: GO:0008116 xref: MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN xref: Reactome:22900 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0001723 name: sphinganine-1-phosphate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde." [EC:4.1.2.27] subset: gosubset_prok synonym: "dihydrosphingosine 1-phosphate aldolase activity" EXACT [EC:4.1.2.27] synonym: "sphinganine-1-phosphate alkanal-lyase activity" EXACT [EC:4.1.2.27] synonym: "sphinganine-1-phosphate lyase activity" EXACT [EC:4.1.2.27] synonym: "sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)" EXACT [EC:4.1.2.27] synonym: "sphinganine-1-phosphate palmitaldehyde-lyase activity" EXACT [EC:4.1.2.27] synonym: "sphingosine-1-phosphate aldolase activity" EXACT [EC:4.1.2.27] synonym: "sphingosine-1-phosphate lyase activity" EXACT [EC:4.1.2.27] xref: EC:4.1.2.27 xref: GO:0008117 xref: GO:0016001 xref: MetaCyc:SPHINGANINE-1-PHOSPHATE-ALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0001724 name: N-acetyllactosaminide alpha-2,3-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein." [EC:2.4.99.6] synonym: "alpha2->3 sialyltransferase activity" EXACT [EC:2.4.99.6] synonym: "CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.6] synonym: "cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase activity" EXACT [EC:2.4.99.6] synonym: "SiaT" RELATED [EC:2.4.99.6] xref: EC:2.4.99.6 xref: GO:0008118 xref: MetaCyc:2.4.99.6-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0001725 name: thiopurine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether." [EC:2.1.1.67] subset: gosubset_prok synonym: "6-thiopurine transmethylase activity" EXACT [EC:2.1.1.67] synonym: "mercaptopurine methyltransferase activity" EXACT [EC:2.1.1.67] synonym: "S-adenosyl-L-methionine:thiopurine S-methyltransferase activity" EXACT [EC:2.1.1.67] synonym: "thiopurine methyltransferase activity" EXACT [EC:2.1.1.67] synonym: "TPMT" RELATED [EC:2.1.1.67] xref: EC:2.1.1.67 xref: GO:0008119 xref: MetaCyc:THIOPURINE-S-METHYLTRANSFERASE-RXN xref: Reactome:22905 is_a: CCO:F0001759 ! S-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001726 name: ceramide glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine." [EC:2.4.1.80] subset: gosubset_prok synonym: "ceramide:UDP-glucose glucosyltransferase activity" EXACT [EC:2.4.1.80] synonym: "ceramide:UDPGlc glucosyltransferase activity" EXACT [EC:2.4.1.80] synonym: "glucosylceramide synthase activity" EXACT [EC:2.4.1.80] synonym: "UDP-glucose-ceramide glucosyltransferase activity" EXACT [EC:2.4.1.80] synonym: "UDP-glucose:ceramide glucosyltransferase activity" EXACT [EC:2.4.1.80] synonym: "UDP-glucose:N-acylsphingosine D-glucosyltransferase activity" EXACT [EC:2.4.1.80] synonym: "UDPglucose:N-acylsphingosine D-glucosyltransferase activity" EXACT [EC:2.4.1.80] synonym: "uridine diphosphoglucose-ceramide glucosyltransferase activity" EXACT [EC:2.4.1.80] xref: EC:2.4.1.80 xref: GO:0008120 xref: MetaCyc:CERAMIDE-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0001727 name: ubiquinol-cytochrome-c reductase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c." [EC:1.10.2.2, ISBN:0198547684] subset: gosubset_prok synonym: "coenzyme Q-cytochrome c reductase activity" EXACT [EC:1.10.2.2] synonym: "coenzyme QH2-cytochrome c reductase activity" EXACT [EC:1.10.2.2] synonym: "complex III (mitochondrial electron transport) activity" NARROW [EC:1.10.2.2] synonym: "CoQH2-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "cytochrome bc1 complex" RELATED [] synonym: "dihydrocoenzyme Q-cytochrome c reductase activity" EXACT [EC:1.10.2.2] synonym: "mitochondrial electron transport complex III" RELATED [EC:1.10.2.2] synonym: "QH2:cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "reduced coenzyme Q-cytochrome c reductase activity" EXACT [EC:1.10.2.2] synonym: "reduced ubiquinone-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "reduced ubiquinone-cytochrome c reductase, complex III (mitochondrial electron transport)" RELATED [EC:1.10.2.2] synonym: "ubihydroquinol:cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinol-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinol-cytochrome c-2 oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinol-cytochrome c1 oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinol-cytochrome c2 reductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinol:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinone--cytochrome-c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinone-cytochrome b-c1 oxidoreductase activity" EXACT [] synonym: "ubiquinone-cytochrome c oxidoreductase activity" EXACT [EC:1.10.2.2] synonym: "ubiquinone-cytochrome c reductase activity" EXACT [EC:1.10.2.2] xref: EC:1.10.2.2 xref: GO:0008121 xref: MetaCyc:1.10.2.2-RXN is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity is_a: CCO:F0003272 ! oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor [Term] id: CCO:F0001728 name: cholesterol 7-alpha-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O." [EC:1.14.13.17] synonym: "cholesterol 7-alpha-hydroxylase activity" EXACT [] synonym: "cholesterol 7alpha-hydroxylase activity" EXACT [EC:1.14.13.17] synonym: "cholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.13.17] synonym: "cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" EXACT [EC:1.14.13.17] synonym: "cytochrome P450 CYP7A1" NARROW [] xref: EC:1.14.13.17 xref: GO:0008123 xref: MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0001729 name: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4-alpha-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O." [EC:4.2.1.96] subset: gosubset_prok synonym: "(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]" RELATED [EC:4.2.1.96] synonym: "4-alpha-hydroxy-tetrahydropterin dehydratase activity" EXACT [EC:4.2.1.96] synonym: "4a-hydroxytetrahydrobiopterin dehydratase activity" EXACT [] synonym: "4a-hydroxytetrahydrobiopterin hydro-lyase activity" EXACT [EC:4.2.1.96] synonym: "4alpha-hydroxy-tetrahydropterin dehydratase activity" EXACT [EC:4.2.1.96] synonym: "pterin-4-alpha-carbinolamine dehydratase activity" EXACT [] synonym: "pterin-4a-carbinolamine dehydratase activity" EXACT [] synonym: "pterin-4alpha-carbinolamine dehydratase activity" EXACT [EC:4.2.1.96] synonym: "tetrahydrobiopterin dehydratase activity" EXACT [EC:4.2.1.96] xref: EC:4.2.1.96 xref: GO:0008124 xref: MetaCyc:4.2.1.96-RXN xref: Reactome:22934 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001730 name: pancreatic elastase I activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa." [EC:3.4.21.36] synonym: "elaszym" RELATED [EC:3.4.21.36] synonym: "pancreatopeptidase E activity" EXACT [EC:3.4.21.36] synonym: "serine elastase" BROAD [EC:3.4.21.36] xref: EC:3.4.21.36 xref: GO:0008125 xref: MetaCyc:3.4.21.36-RXN is_a: CCO:F0001736 ! pancreatic elastase activity [Term] id: CCO:F0001731 name: acetylesterase activity namespace: molecular_function def: "Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate." [EC:3.1.1.6] subset: gosubset_prok synonym: "acetic ester hydrolase activity" EXACT [EC:3.1.1.6] synonym: "acetic-ester acetylhydrolase activity" EXACT [EC:3.1.1.6] synonym: "C-esterase (in animal tissues)" NARROW [EC:3.1.1.6] synonym: "chloroesterase" NARROW [EC:3.1.1.6] synonym: "citrus acetylesterase" NARROW [EC:3.1.1.6] synonym: "p-nitrophenyl acetate esterase" NARROW [EC:3.1.1.6] xref: EC:3.1.1.6 xref: GO:0008126 xref: MetaCyc:ACETYLESTERASE-RXN xref: UM-BBD_enzymeID:e0052 is_a: CCO:F0008362 ! short-chain carboxylesterase activity [Term] id: CCO:F0001732 name: quercetin 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: quercetin + O2 = 2-protocatechuoylphloroglucinolcarboxylate + CO." [EC:1.13.11.24] synonym: "flavonol 2,4-oxygenase activity" EXACT [EC:1.13.11.24] synonym: "quercetin:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.24] synonym: "quercetinase activity" EXACT [EC:1.13.11.24] xref: EC:1.13.11.24 xref: GO:0008127 xref: MetaCyc:QUERCETIN-23-DIOXYGENASE-RXN xref: UM-BBD_enzymeID:e0559 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0001733 name: actinidain activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'." [EC:3.4.22.14] synonym: "actinidia anionic protease activity" NARROW [EC:3.4.22.14] synonym: "actinidin activity" EXACT [EC:3.4.22.14] synonym: "proteinase A2 of actinidia chinensis" RELATED [EC:3.4.22.14] xref: EC:3.4.22.14 xref: GO:0008129 xref: MetaCyc:3.4.22.14-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0001734 name: neutrophil collagenase activity namespace: molecular_function def: "Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I." [EC:3.4.24.34] synonym: "matrix metalloproteinase 8 activity" EXACT [EC:3.4.24.34] synonym: "MMP-8" EXACT [] synonym: "PMNL collagenase activity" EXACT [EC:3.4.24.34] xref: EC:3.4.24.34 xref: GO:0008130 xref: MetaCyc:3.4.24.34-RXN is_a: CCO:F0001737 ! collagenase activity [Term] id: CCO:F0001735 name: amine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: R-CH2-NH2 + H2O + O2 = R-CHO + NH3 + H2O2." [EC:1.4.3.4, EC:1.4.3.6] subset: gosubset_prok synonym: "adrenalin oxidase" NARROW [EC:1.4.3.4] synonym: "adrenaline oxidase activity" NARROW [EC:1.4.3.4] synonym: "amine oxidase (copper-containing) activity" NARROW [] synonym: "amine oxidase (flavin-containing) activity" NARROW [] synonym: "amine oxidase (pyridoxal containing)" NARROW [EC:1.4.3.4] synonym: "amine oxygen oxidoreductase activity" EXACT [EC:1.4.3.4] synonym: "amine:oxygen oxidoreductase (deaminating) (copper-containing)" NARROW [EC:1.4.3.6] synonym: "amine:oxygen oxidoreductase (deaminating) (flavin-containing)" NARROW [EC:1.4.3.4] synonym: "benzylamine oxidase" NARROW [EC:1.4.3.4] synonym: "Cu-amine oxidase activity" NARROW [EC:1.4.3.6] synonym: "DAO activity" NARROW [EC:1.4.3.4] synonym: "diamine oxidase activity" NARROW [EC:1.4.3.6] synonym: "diamine:O2 oxidoreductase (deaminating)" NARROW [EC:1.4.3.6] synonym: "diamino oxhydrase activity" NARROW [EC:1.4.3.4] synonym: "epinephrine oxidase" NARROW [EC:1.4.3.4] synonym: "histaminase activity" NARROW [EC:1.4.3.6] synonym: "histamine deaminase" NARROW [EC:1.4.3.6] synonym: "histamine oxidase" NARROW [EC:1.4.3.6] synonym: "MAO" RELATED [EC:1.4.3.4] synonym: "monoamine oxidase activity" NARROW [EC:1.4.3.4] synonym: "monoamine:O2 oxidoreductase (deaminating)" NARROW [EC:1.4.3.4] synonym: "semicarbazide-sensitive amine oxidase" NARROW [EC:1.4.3.6] synonym: "serotonin deaminase" NARROW [EC:1.4.3.4] synonym: "spermidine oxidase" NARROW [EC:1.4.3.4] synonym: "spermine oxidase" NARROW [EC:1.4.3.4] synonym: "SSAO" RELATED [EC:1.4.3.4] synonym: "tyraminase activity" NARROW [EC:1.4.3.4] synonym: "tyramine oxidase activity" NARROW [EC:1.4.3.4] xref: EC:1.4.3.4 xref: EC:1.4.3.6 xref: GO:0004041 xref: GO:0008122 xref: GO:0008131 xref: MetaCyc:AMINE-OXIDASE-(FLAVIN-CONTAINING)-RXN xref: MetaCyc:AMINEOXID-RXN xref: Reactome:7141 is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0001736 name: pancreatic elastase activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins, including elastin." [EC:3.4.21.36, EC:3.4.21.71] xref: EC:3.4.21.- xref: GO:0008132 is_a: CCO:F0000698 ! serine-type endopeptidase activity is_a: CCO:F0005704 ! elastase activity [Term] id: CCO:F0001737 name: collagenase activity namespace: molecular_function xref: EC:3.4.24.- xref: GO:0008133 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0001738 name: transcription factor binding namespace: molecular_function def: "Interacting selectively with a transcription factor, any protein required to initiate or regulate transcription." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "TF binding" EXACT [] xref: GO:0008134 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001739 name: translation factor activity, nucleic acid binding namespace: molecular_function def: "Functions during translation by binding nucleic acids during polypeptide synthesis at the ribosome." [GOC:ai] subset: goslim_generic subset: goslim_plant subset: gosubset_prok xref: GO:0008135 is_a: CCO:F0000273 ! nucleic acid binding is_a: CCO:F0006094 ! translation regulator activity [Term] id: CCO:F0001740 name: NADH dehydrogenase (ubiquinone) activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol." [EC:1.6.5.3] subset: gosubset_prok synonym: "coenzyme Q reductase activity" EXACT [EC:1.6.5.3] synonym: "complex 1 dehydrogenase activity" RELATED [EC:1.6.5.3] synonym: "complex I (electron transport chain) activity" RELATED [EC:1.6.5.3] synonym: "complex I (mitochondrial electron transport) activity" RELATED [EC:1.6.5.3] synonym: "complex I (NADH:Q1 oxidoreductase) activity" RELATED [EC:1.6.5.3] synonym: "dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity" EXACT [EC:1.6.5.3] synonym: "DPNH-coenzyme Q reductase activity" EXACT [EC:1.6.5.3] synonym: "DPNH-ubiquinone reductase activity" EXACT [EC:1.6.5.3] synonym: "electron transfer complex I activity" RELATED [EC:1.6.5.3] synonym: "mitochondrial electron transport complex 1 activity" NARROW [EC:1.6.5.3] synonym: "mitochondrial electron transport complex I activity" NARROW [EC:1.6.5.3] synonym: "NADH coenzyme Q1 reductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-coenzyme Q oxidoreductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-coenzyme Q reductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-CoQ oxidoreductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-CoQ reductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-Q6 oxidoreductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-ubiquinone oxidoreductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-ubiquinone reductase activity" EXACT [EC:1.6.5.3] synonym: "NADH-ubiquinone-1 reductase activity" EXACT [EC:1.6.5.3] synonym: "NADH:ubiquinone oxidoreductase activity" EXACT [EC:1.6.5.3] synonym: "NADH:ubiquinone oxidoreductase complex activity" RELATED [EC:1.6.5.3] synonym: "reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity" EXACT [EC:1.6.5.3] synonym: "type 1 dehydrogenase activity" RELATED [EC:1.6.5.3] synonym: "ubiquinone reductase activity" EXACT [] xref: EC:1.6.5.3 xref: GO:0008137 xref: MetaCyc:NADH-DEHYDROG-RXN xref: Reactome:22973 is_a: CCO:F0007489 ! NADH dehydrogenase (quinone) activity [Term] id: CCO:F0001741 name: protein tyrosine/serine/threonine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: protein serine/threonine/tyrosine phosphate + H2O = protein serine/threonine/tyrosine + phosphate." [GOC:mah] subset: gosubset_prok synonym: "dual-specificity protein phosphatase" BROAD [] xref: EC:3.1.3.- xref: GO:0008138 is_a: CCO:F0001086 ! phosphoprotein phosphatase activity [Term] id: CCO:F0001742 name: nuclear localization sequence binding namespace: molecular_function def: "Interacting selectively with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus." [GOC:ai] synonym: "NLS binding" EXACT [] synonym: "nuclear localization signal binding" EXACT [] xref: GO:0008139 is_a: CCO:F0001368 ! signal sequence binding [Term] id: CCO:F0001743 name: cAMP response element binding protein binding namespace: molecular_function synonym: "3',5' cAMP response element binding protein binding" EXACT [] synonym: "3',5'-cAMP response element binding protein binding" EXACT [] synonym: "adenosine 3',5'-cyclophosphate response element binding protein binding" EXACT [] synonym: "cyclic AMP response element binding protein binding" EXACT [] xref: GO:0008140 is_a: CCO:F0000300 ! transcription coactivator activity [Term] id: CCO:F0001744 name: oxysterol binding namespace: molecular_function def: "Interacting selectively with oxysterol, an oxidized form of cholesterol." [http://www.onelook.com/] xref: GO:0008142 is_a: CCO:F0005049 ! sterol binding [Term] id: CCO:F0001745 name: poly(A) binding namespace: molecular_function def: "Interacting selectively with the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "poly-A binding" EXACT [] synonym: "polyadenylate binding" EXACT [] xref: GO:0008143 is_a: CCO:F0000312 ! single-stranded RNA binding is_a: CCO:F0000313 ! mRNA binding [Term] id: CCO:F0001746 name: drug binding namespace: molecular_function def: "Interacting selectively with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0008144 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0001747 name: phenylalkylamine binding namespace: molecular_function def: "Interacting selectively with phenylalkylamine or any of its derivatives." [GOC:jl] xref: GO:0008145 is_a: CCO:F0001746 ! drug binding [Term] id: CCO:F0001748 name: sulfotransferase activity namespace: molecular_function def: "Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate." [http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "sulphotransferase activity" EXACT [] xref: EC:2.8.2 xref: GO:0008146 xref: Reactome:2397 is_a: CCO:F0003354 ! transferase activity, transferring sulfur-containing groups [Term] id: CCO:F0001749 name: structural constituent of bone namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of bone." [GOC:mah] xref: GO:0008147 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001750 name: negative transcription elongation factor activity namespace: molecular_function def: "Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation." [GOC:mah] xref: GO:0008148 is_a: CCO:F0000298 ! transcription elongation regulator activity [Term] id: CCO:F0001751 name: protein phosphatase 1 binding namespace: molecular_function def: "Interacting selectively with the enzyme protein phosphatase 1." [GOC:jl] xref: GO:0008157 is_a: CCO:F0004212 ! protein phosphatase binding [Term] id: CCO:F0001752 name: hedgehog receptor activity namespace: molecular_function def: "Combining with the hedgehog protein to initiate a change in cell activity." [GOC:go_curators] synonym: "patched activity" EXACT [] xref: GO:0008158 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001753 name: positive transcription elongation factor activity namespace: molecular_function def: "Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation." [GOC:mah] xref: GO:0008159 is_a: CCO:F0000298 ! transcription elongation regulator activity [Term] id: CCO:F0001754 name: protein tyrosine phosphatase activator activity namespace: molecular_function def: "Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0008160 is_a: CCO:F0004134 ! phosphatase activator activity [Term] id: CCO:F0001755 name: methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to an acceptor molecule." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "methylase" BROAD [] xref: EC:2.1.1 xref: GO:0004480 xref: GO:0008168 xref: Reactome:1062 is_a: CCO:F0003317 ! transferase activity, transferring one-carbon groups [Term] id: CCO:F0001756 name: C-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008169 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0001757 name: N-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008170 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0001758 name: O-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008171 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0001759 name: S-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008172 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0001760 name: RNA methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule." [GOC:mah] comment: Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698). subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008173 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0001761 name: mRNA methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008174 is_a: CCO:F0001760 ! RNA methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0001762 name: tRNA methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008175 is_a: CCO:F0001760 ! RNA methyltransferase activity [Term] id: CCO:F0001763 name: tRNA (guanine-N7-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine." [EC:2.1.1.33] subset: gosubset_prok synonym: "7-methylguanine transfer ribonucleate methylase activity" EXACT [EC:2.1.1.33] synonym: "N7-methylguanine methylase activity" EXACT [EC:2.1.1.33] synonym: "S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase activity" EXACT [EC:2.1.1.33] synonym: "S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase activity" EXACT [EC:2.1.1.33] synonym: "transfer ribonucleate guanine 7-methyltransferase activity" EXACT [EC:2.1.1.33] synonym: "tRNA guanine 7-methyltransferase activity" EXACT [EC:2.1.1.33] xref: EC:2.1.1.33 xref: GO:0008176 xref: MetaCyc:TRNA-(GUANINE-N7-)-METHYLTRANSFERASE-RXN is_a: CCO:F0003146 ! tRNA (guanine) methyltransferase activity [Term] id: CCO:F0001764 name: succinate dehydrogenase (ubiquinone) activity namespace: molecular_function def: "Catalysis of the reaction: succinate + quinone = fumarate + quinol." [EC:1.3.5.1] subset: gosubset_prok synonym: "complex II" RELATED [EC:1.3.5.1] synonym: "fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)" RELATED [EC:1.3.5.1] synonym: "menaquinol: fumarate oxidoreductase activity" EXACT [EC:1.3.5.1] synonym: "quinol:fumarate oxidoreductase activity" EXACT [] synonym: "succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)" RELATED [EC:1.3.5.1] synonym: "succinate:ubiquinone oxidoreductase activity" EXACT [EC:1.3.5.1] synonym: "succinic dehydrogenase activity" BROAD [EC:1.3.5.1] xref: EC:1.3.5.1 xref: GO:0008177 xref: GO:0019737 xref: Reactome:23070 is_a: CCO:F0003236 ! oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor [Term] id: CCO:F0001765 name: adenylate cyclase binding namespace: molecular_function def: "Interacting selectively with the enzyme adenylate cyclase." [GOC:jl] synonym: "adenylyl cyclase binding" EXACT [] xref: GO:0008179 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0001766 name: glycogen phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate." [EC:2.4.1.1, MetaCyc:GLYCOPHOSPHORYL-RXN] subset: gosubset_prok xref: GO:0008184 xref: MetaCyc:GLYCOPHOSPHORYL-RXN xref: Reactome:23099 is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0001767 name: RNA-dependent ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of RNA; drives another reaction." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "RNA-dependent adenosinetriphosphatase activity" EXACT [] xref: GO:0004010 xref: GO:0008186 is_a: CCO:F0005696 ! ATPase activity, coupled [Term] id: CCO:F0001768 name: poly-pyrimidine tract binding namespace: molecular_function def: "Interacting selectively with any stretch of pyrimidines (cytosine or uracil) in an RNA molecule." [GOC:jl] xref: GO:0008187 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0001769 name: neuropeptide receptor activity namespace: molecular_function def: "Combining with a neuropeptide to initiate a change in cell activity." [GOC:ai] xref: GO:0008188 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled is_a: CCO:F0004488 ! neurotransmitter receptor activity is_a: CCO:F0005746 ! neuropeptide binding [Term] id: CCO:F0001770 name: eukaryotic initiation factor 4E binding namespace: molecular_function def: "Interacting selectively with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "eIF4E binding" EXACT [] xref: GO:0008190 is_a: CCO:F0004653 ! translation initiation factor binding [Term] id: CCO:F0001771 name: metalloendopeptidase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides and contain a chelated metal ion at their active sites which is essential to their catalytic activity." [GOC:ai] subset: gosubset_prok synonym: "metalloprotease inhibitor" BROAD [] synonym: "metalloproteinase inhibitor" BROAD [] xref: GO:0008191 is_a: CCO:F0001222 ! endopeptidase inhibitor activity [Term] id: CCO:F0001772 name: RNA guanylyltransferase activity namespace: molecular_function def: "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule." [GOC:mah] xref: EC:2.7.7.- xref: GO:0008192 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0001773 name: tRNA guanylyltransferase activity namespace: molecular_function def: "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs." [PMID:1660461] xref: EC:2.7.7.- xref: GO:0008193 is_a: CCO:F0001772 ! RNA guanylyltransferase activity [Term] id: CCO:F0001774 name: UDP-glycosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule." [InterPro:IPR004224, PMID:11846783] subset: gosubset_prok xref: GO:0008194 xref: Reactome:23123 is_a: CCO:F0003332 ! transferase activity, transferring glycosyl groups [Term] id: CCO:F0001775 name: phosphatidate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-sn-phosphatidate + H2O = a 1,2-diacyl-sn-glycerol + phosphate." [EC:3.1.3.4] synonym: "3-sn-phosphatidate phosphohydrolase activity" EXACT [EC:3.1.3.4] synonym: "acid phosphatidyl phosphatase activity" EXACT [EC:3.1.3.4] synonym: "phosphatic acid phosphatase activity" EXACT [EC:3.1.3.4] synonym: "phosphatic acid phosphohydrolase activity" EXACT [EC:3.1.3.4] synonym: "phosphatidate phosphohydrolase activity" EXACT [] synonym: "phosphatidic acid phosphatase activity" EXACT [EC:3.1.3.4] xref: EC:3.1.3.4 xref: GO:0004606 xref: GO:0008195 xref: MetaCyc:PHOSPHATIDATE-PHOSPHATASE-RXN xref: Reactome:23125 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0001776 name: vitellogenin receptor activity namespace: molecular_function def: "Combining with vitellogenin to initiate a change in cell activity." [GOC:ai] xref: GO:0008196 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0001777 name: ferrous iron binding namespace: molecular_function def: "Interacting selectively with ferrous iron, Fe(II)." [GOC:ai] subset: gosubset_prok xref: GO:0008198 is_a: CCO:F0001643 ! iron ion binding [Term] id: CCO:F0001778 name: ferric iron binding namespace: molecular_function def: "Interacting selectively with ferric iron, Fe(III)." [GOC:ai] subset: gosubset_prok xref: GO:0008199 is_a: CCO:F0001643 ! iron ion binding [Term] id: CCO:F0001779 name: ion channel inhibitor activity namespace: molecular_function subset: gosubset_prok xref: GO:0008200 is_a: CCO:F0003087 ! channel inhibitor activity [Term] id: CCO:F0001780 name: heparin binding namespace: molecular_function def: "Interacting selectively with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha1-4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "heparan sulfate binding" RELATED [] xref: GO:0008201 is_a: CCO:F0001663 ! glycosaminoglycan binding [Term] id: CCO:F0001781 name: tyramine receptor activity namespace: molecular_function def: "Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine." [http://www.onelook.com/] xref: GO:0008226 is_a: CCO:F0001782 ! amine receptor activity [Term] id: CCO:F0001782 name: amine receptor activity namespace: molecular_function def: "Combining with a biogenic amine to initiate a change in cell activity." [GOC:dph] subset: gosubset_prok synonym: "biogenic amine receptor" NARROW [] xref: GO:0008227 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001783 name: peptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds." [GOC:jl] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_yeast subset: gosubset_prok synonym: "hydrolase, acting on peptide bonds" EXACT [] synonym: "peptide hydrolase activity" EXACT [] synonym: "protease activity" EXACT [] xref: EC:3.4 xref: GO:0008233 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0001784 name: cysteine-type peptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "cysteine protease activity" EXACT [] synonym: "thiol protease activity" EXACT [] xref: EC:3.4.-.- xref: GO:0004220 xref: GO:0008234 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0001785 name: metalloexopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal peptide linkages in oligopeptides or polypeptides. Enzymes of this class contain a chelated metal ion essential to their catalytic activity at their active sites." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0008235 is_a: CCO:F0001787 ! metallopeptidase activity is_a: CCO:F0001788 ! exopeptidase activity [Term] id: CCO:F0001786 name: serine-type peptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [http://en.wikipedia.org/wiki/Serine_hydrolase, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "serine protease activity" EXACT [] xref: GO:0008236 is_a: CCO:F0001783 ! peptidase activity is_a: CCO:F0003609 ! serine hydrolase activity [Term] id: CCO:F0001787 name: metallopeptidase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008237 xref: Reactome:1795 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0001788 name: exopeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of the terminal or penultimate peptide bond of a peptide chain, releasing a single amino acid or dipeptide. Exopeptidases are classified as aminopeptidases, carboxypeptidases, dipeptidases, and omega peptidases." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok synonym: "exoprotease activity" EXACT [] xref: GO:0008238 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0001789 name: dipeptidyl-peptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain." [GOC:mb] subset: gosubset_prok xref: GO:0008239 is_a: CCO:F0003376 ! dipeptidyl-peptidase and tripeptidyl-peptidase activity [Term] id: CCO:F0001790 name: tripeptidyl-peptidase activity namespace: molecular_function def: "Catalysis of the release of an N-terminal tripeptide from a polypeptide." [GOC:mah] xref: EC:3.4.14.- xref: GO:0008240 is_a: CCO:F0001786 ! serine-type peptidase activity is_a: CCO:F0003376 ! dipeptidyl-peptidase and tripeptidyl-peptidase activity [Term] id: CCO:F0001791 name: peptidyl-dipeptidase activity namespace: molecular_function def: "Catalysis of the release of C-terminal dipeptides from a polypeptide chain." [GOC:mb] subset: gosubset_prok xref: EC:3.4.15 xref: GO:0008241 is_a: CCO:F0001788 ! exopeptidase activity [Term] id: CCO:F0001792 name: omega peptidase activity namespace: molecular_function def: "Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of a-carboxyl to a-amino groups)." [EC:3.4.19.-] subset: gosubset_prok xref: EC:3.4.19 xref: GO:0008242 is_a: CCO:F0001788 ! exopeptidase activity [Term] id: CCO:F0001793 name: plasminogen activator activity namespace: molecular_function def: "Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin." [EC:3.4.21.68, EC:3.4.21.73] subset: gosubset_prok synonym: "abbokinase activity" EXACT [EC:3.4.21.68] synonym: "cellular plasminogen activator activity" NARROW [EC:3.4.21.-] synonym: "double-chain urokinase-type plasminogen activator" RELATED [EC:3.4.21.68] synonym: "plasminogen activator, tissue-type" RELATED [EC:3.4.21.68] synonym: "t-PA" RELATED [EC:3.4.21.68] synonym: "t-plasminogen activator activity" NARROW [] synonym: "tissue plasminogen activator activity" NARROW [EC:3.4.21.-] synonym: "tissue-type plasminogen activator activity" RELATED [EC:3.4.21.-] synonym: "tPA activity" NARROW [EC:3.4.21.-] synonym: "two-chain urokinase-type plasminogen activator" RELATED [EC:3.4.21.68] synonym: "u-PA" RELATED [EC:3.4.21.68] synonym: "u-plasminogen activator activity" NARROW [] synonym: "uPA" RELATED [EC:3.4.21.68] synonym: "urinary esterase A" RELATED [EC:3.4.21.68] synonym: "urinary plasminogen activator activity" NARROW [EC:3.4.21.-] synonym: "urokinase activity" RELATED [EC:3.4.21.-] synonym: "urokinase plasminogen activator" RELATED [EC:3.4.21.68] synonym: "urokinase-type plasminogen activator" RELATED [EC:3.4.21.68] xref: EC:3.4.21.- xref: EC:3.4.21.68 xref: EC:3.4.21.73 xref: GO:0004296 xref: GO:0004297 xref: GO:0008243 xref: MetaCyc:3.4.21.68-RXN xref: MetaCyc:3.4.21.73-RXN xref: Reactome:9757 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0001794 name: tRNA-specific adenosine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule." [GOC:mah, IMG:00700] subset: gosubset_prok synonym: "tRNA-adenosine deaminase activity" EXACT [] xref: EC:3.5.4.- xref: GO:0008251 is_a: CCO:F0000485 ! adenosine deaminase activity [Term] id: CCO:F0001795 name: nucleotidase activity namespace: molecular_function def: "Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate." [EC:3.1.3.31] subset: gosubset_prok synonym: "acid nucleotidase activity" EXACT [EC:3.1.3.31] synonym: "deoxyinosine-activated nucleotidase (DIAN)" EXACT [EC:3.1.3.31] synonym: "deoxyribonucleoside-activated nucleotidase (DAN)" EXACT [EC:3.1.3.31] synonym: "NSP I" RELATED [EC:3.1.3.31] synonym: "NSP II" RELATED [EC:3.1.3.31] synonym: "nucleotide phosphohydrolase activity" EXACT [EC:3.1.3.31] synonym: "nucleotide-specific phosphatase activity" EXACT [EC:3.1.3.31] xref: EC:3.1.3.31 xref: GO:0008252 xref: MetaCyc:NUCLEOTIDASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0001796 name: 5'-nucleotidase activity namespace: molecular_function def: "Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate." [EC:3.1.3.5] subset: gosubset_prok synonym: "5' nucleotidase activity" EXACT [] synonym: "5'-adenylic phosphatase" NARROW [EC:3.1.3.5] synonym: "5'-AMP nucleotidase" NARROW [EC:3.1.3.5] synonym: "5'-AMPase" NARROW [EC:3.1.3.5] synonym: "5'-mononucleotidase activity" EXACT [EC:3.1.3.5] synonym: "5'-ribonucleotide phosphohydrolase activity" EXACT [EC:3.1.3.5] synonym: "adenosine 5'-phosphatase" NARROW [EC:3.1.3.5] synonym: "adenosine monophosphatase" NARROW [EC:3.1.3.5] synonym: "AMP phosphatase" NARROW [EC:3.1.3.5] synonym: "AMP phosphohydrolase" NARROW [EC:3.1.3.5] synonym: "AMPase" NARROW [EC:3.1.3.5] synonym: "snake venom 5'-nucleotidase" NARROW [EC:3.1.3.5] synonym: "thimidine monophosphate nucleotidase" NARROW [EC:3.1.3.5] synonym: "UMPase" NARROW [EC:3.1.3.5] synonym: "uridine 5'-nucleotidase" NARROW [EC:3.1.3.5] xref: EC:3.1.3.5 xref: GO:0008253 xref: Reactome:23614 is_a: CCO:F0001795 ! nucleotidase activity [Term] id: CCO:F0001797 name: 3'-nucleotidase activity namespace: molecular_function def: "Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate." [EC:3.1.3.6] synonym: "3' nucleotidase activity" EXACT [] synonym: "3'-mononucleotidase activity" EXACT [EC:3.1.3.6] synonym: "3'-phosphatase activity" EXACT [EC:3.1.3.6] synonym: "3'-ribonucleotidase activity" EXACT [EC:3.1.3.6] synonym: "3'-ribonucleotide phosphohydrolase activity" EXACT [EC:3.1.3.6] xref: EC:3.1.3.6 xref: GO:0008254 xref: MetaCyc:3-NUCLEOTID-RXN is_a: CCO:F0001795 ! nucleotidase activity [Term] id: CCO:F0001798 name: ecdysis-triggering hormone activity namespace: molecular_function xref: GO:0008255 is_a: CCO:F0001481 ! neuropeptide hormone activity [Term] id: CCO:F0001799 name: protein histidine pros-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine." [EC:2.7.13.1] subset: gosubset_prok synonym: "ATP:protein-L-histidine N-pros-phosphotransferase activity" EXACT [EC:2.7.13.1] synonym: "ATP:protein-L-histidine Npi-phosphotransferase activity" EXACT [EC:2.7.13.1] synonym: "HK2" RELATED [EC:2.7.13.1] synonym: "protein-histidine pros-kinase activity" EXACT [EC:2.7.13.1] xref: EC:2.7.13.1 xref: GO:0008256 xref: MetaCyc:PROTEIN-HISTIDINE-PROS-KINASE-RXN is_a: CCO:F0001044 ! protein histidine kinase activity [Term] id: CCO:F0001800 name: protein histidine tele-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine." [EC:2.7.13.2] synonym: "ATP:protein-L-histidine N-tele-phosphotransferase activity" EXACT [EC:2.7.13.2] synonym: "ATP:protein-L-histidine Ntau-phosphotransferase activity" EXACT [EC:2.7.13.2] synonym: "HK3" RELATED [EC:2.7.13.2] synonym: "protein-histidine tele-kinase activity" EXACT [EC:2.7.13.2] xref: EC:2.7.13.2 xref: GO:0008257 xref: MetaCyc:PROTEIN-HISTIDINE-TELE-KINASE-RXN is_a: CCO:F0001044 ! protein histidine kinase activity [Term] id: CCO:F0001801 name: 3-oxoacid CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA." [EC:2.8.3.5] subset: gosubset_prok synonym: "3-ketoacid CoA-transferase activity" EXACT [EC:2.8.3.5] synonym: "3-ketoacid coenzyme A transferase activity" EXACT [EC:2.8.3.5] synonym: "3-oxo-CoA transferase activity" EXACT [EC:2.8.3.5] synonym: "3-oxoacid CoA dehydrogenase activity" EXACT [EC:2.8.3.5] synonym: "3-oxoacid coenzyme A-transferase activity" EXACT [EC:2.8.3.5] synonym: "acetoacetate succinyl-CoA transferase activity" EXACT [EC:2.8.3.5] synonym: "acetoacetyl coenzyme A-succinic thiophorase activity" EXACT [EC:2.8.3.5] synonym: "succinyl coenzyme A-acetoacetyl coenzyme A-transferase activity" EXACT [EC:2.8.3.5] synonym: "succinyl-CoA transferase activity" EXACT [EC:2.8.3.5] synonym: "succinyl-CoA:3-ketoacid-CoA transferase activity" EXACT [EC:2.8.3.5] synonym: "succinyl-CoA:3-oxo-acid CoA-transferase activity" EXACT [EC:2.8.3.5] xref: EC:2.8.3.5 xref: GO:0008260 xref: MetaCyc:3-OXOACID-COA-TRANSFERASE-RXN xref: Reactome:23643 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0001802 name: allatostatin receptor activity namespace: molecular_function def: "Combining with allatostatin to initiate a change in cell activity." [GOC:ai] xref: GO:0008261 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0001803 name: importin-alpha export receptor activity namespace: molecular_function def: "Interacting selectively with importin-alpha to mediate its transfer through the nuclear pore to the cytoplasm." [GOC:mah, GOC:vw, PMID:12486120] synonym: "importin-alpha binding" RELATED [] xref: GO:0008262 is_a: CCO:F0001369 ! nuclear export signal receptor activity is_a: CCO:F0001997 ! protein transporter activity [Term] id: CCO:F0001804 name: pyrimidine-specific mismatch base pair DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site." [GOC:elh, PMID:9224623] synonym: "G/T-mismatch-specific thymine-DNA glycosylase activity" EXACT [] xref: GO:0008263 is_a: CCO:F0000093 ! mismatch base pair DNA N-glycosylase activity [Term] id: CCO:F0001805 name: Mo-molybdopterin cofactor sulfurase activity namespace: molecular_function synonym: "Mo-molybdopterin cofactor sulphurase activity" EXACT [] synonym: "molybdopterin cofactor sulfurase activity" EXACT [] synonym: "molybdopterin synthase sulfurylase activity" EXACT [] xref: GO:0008265 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0001806 name: poly(U) binding namespace: molecular_function def: "Interacting selectively with a sequence of uracil residues in an RNA molecule." [GOC:mah] xref: GO:0008266 is_a: CCO:F0000312 ! single-stranded RNA binding [Term] id: CCO:F0001807 name: poly-glutamine tract binding namespace: molecular_function def: "Interacting selectively with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein." [GOC:mah] xref: GO:0008267 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0001808 name: receptor signaling protein tyrosine kinase signaling protein activity namespace: molecular_function synonym: "receptor signalling protein tyrosine kinase signalling protein activity" EXACT [] xref: GO:0008268 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0001809 name: JAK pathway signal transduction adaptor activity namespace: molecular_function def: "The binding activity of a molecule that brings together a molecule of the JAK signal transduction pathway and one or more other molecules of the pathway, permitting them to function in a coordinated way." [GOC:mtg_MIT] xref: GO:0008269 is_a: CCO:F0001808 ! receptor signaling protein tyrosine kinase signaling protein activity is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0001810 name: zinc ion binding namespace: molecular_function def: "Interacting selectively with zinc (Zn) ions." [GOC:ai] subset: gosubset_prok synonym: "zinc binding" EXACT [] xref: GO:0008270 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0001811 name: secondary active sulfate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the secondary active transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] subset: gosubset_prok synonym: "secondary active sulphate transmembrane transporter activity" EXACT [] synonym: "sulfate porter activity" RELATED [] synonym: "sulphate porter activity" EXACT [] xref: GO:0008271 is_a: CCO:F0002594 ! sulfate transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001812 name: calcium, potassium:sodium antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in)." [TC:2.A.19.4.1] synonym: "potassium-dependent sodium/calcium exchanger" RELATED [] xref: GO:0008273 is_a: CCO:F0002795 ! calcium:cation antiporter activity [Term] id: CCO:F0001813 name: protein methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group (CH3-) to a protein." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008276 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0001814 name: sulfonylurea receptor activity namespace: molecular_function def: "Combining with sulfonylurea to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'potassium channel activity ; GO:0005267'. synonym: "sulphonylurea receptor activity" EXACT [] xref: GO:0008281 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0001815 name: boss receptor activity namespace: molecular_function def: "Combining with the protein bride of sevenless (boss) to initiate a change in cell activity." [GOC:jl] synonym: "sevenless receptor activity" RELATED [] xref: GO:0008288 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity [Term] id: CCO:F0001816 name: lipid binding namespace: molecular_function def: "Interacting selectively with a lipid." [GOC:ai] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: GO:0008289 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0001817 name: calcium- and calmodulin-responsive adenylate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin." [EC:4.6.1.1, GOC:mah] synonym: "calcium- and calmodulin-responsive adenylyl cyclase activity" EXACT [] synonym: "calcium/calmodulin-responsive adenylate cyclase activity" EXACT [] xref: GO:0008294 xref: Reactome:23748 is_a: CCO:F0000494 ! adenylate cyclase activity [Term] id: CCO:F0001818 name: 3'-5'-exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule." [GOC:mah] synonym: "3'-5' exodeoxyribonuclease activity" EXACT [] xref: GO:0008296 is_a: CCO:F0001875 ! 3'-5' exonuclease activity is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0001819 name: single-stranded DNA specific exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule." [GOC:mah] subset: gosubset_prok xref: GO:0008297 is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0001820 name: DNA bending activity namespace: molecular_function def: "The function of causing local conformational micropolymorphism of DNA in which the original B-DNA structure is only distorted but not extensively modified." [GOC:jl, PMID:10710711] subset: gosubset_prok xref: GO:0008301 is_a: CCO:F0000274 ! DNA binding [Term] id: CCO:F0001821 name: structural constituent of muscle namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a muscle fiber." [GOC:mah] xref: GO:0008307 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001822 name: voltage-gated anion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion." [GOC:mtg_transport, ISBN:0815340729] synonym: "voltage-dependent ion-selective channel activity" RELATED [] synonym: "voltage-gated ion-selective channel activity" RELATED [] xref: GO:0008308 xref: GO:0022844 is_a: CCO:F0001512 ! voltage-gated ion channel activity is_a: CCO:F0001521 ! anion channel activity [Term] id: CCO:F0001823 name: double-stranded DNA specific exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule." [GOC:mah] xref: GO:0008309 is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0001824 name: single-stranded DNA specific 3'-5' exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule." [GOC:mah] xref: GO:0008310 is_a: CCO:F0001818 ! 3'-5'-exodeoxyribonuclease activity is_a: CCO:F0001819 ! single-stranded DNA specific exodeoxyribonuclease activity [Term] id: CCO:F0001825 name: double-stranded DNA specific 3'-5' exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule." [GOC:mah] xref: GO:0008311 is_a: CCO:F0001818 ! 3'-5'-exodeoxyribonuclease activity is_a: CCO:F0001823 ! double-stranded DNA specific exodeoxyribonuclease activity [Term] id: CCO:F0001826 name: 7S RNA binding namespace: molecular_function def: "Interacting selectively with 7S RNA, the RNA component of the signal recognition particle (SRP)." [GOC:jl, UniProtKB:P37108] subset: gosubset_prok xref: GO:0008312 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0001827 name: gurken receptor activity namespace: molecular_function def: "Combining with the ligand Gurken to initiate a change in cell activity." [GOC:bf] xref: GO:0008313 is_a: CCO:F0001343 ! epidermal growth factor receptor activity [Term] id: CCO:F0001828 name: structural constituent of vitelline membrane namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg." [GOC:mah, GOC:sensu] synonym: "structural constituent of vitelline membrane (sensu Insecta)" NARROW [] xref: GO:0008316 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0001829 name: gurken receptor binding namespace: molecular_function def: "Interacting selectively with the gurken growth factor receptor." [GOC:ai] synonym: "gurken receptor ligand" NARROW [] xref: GO:0008317 is_a: CCO:F0001456 ! epidermal growth factor receptor binding [Term] id: CCO:F0001830 name: protein prenyltransferase activity namespace: molecular_function def: "Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein." [GOC:mah] xref: EC:2.5.1.- xref: GO:0008244 xref: GO:0008318 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0001831 name: prenyl protein specific endopeptidase activity namespace: molecular_function xref: EC:3.4.24.- xref: GO:0008319 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0001832 name: protein transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a protein from one side of a membrane to the other." [GOC:jl] subset: gosubset_prok xref: GO:0008320 is_a: CCO:F0001646 ! protein binding is_a: CCO:F0001997 ! protein transporter activity is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0001833 name: Ral guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] xref: GO:0008321 is_a: CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity [Term] id: CCO:F0001834 name: Pro-X carboxypeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a Pro-Xaa bond to release a C-terminal amino acid." [GOC:mah] xref: GO:0008322 is_a: CCO:F0000649 ! carboxypeptidase activity [Term] id: CCO:F0001835 name: cation transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cation from one side of the membrane to the other." [GOC:df, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "transmembrane cation transporter activity" EXACT [] xref: GO:0008324 is_a: CCO:F0002557 ! ion transmembrane transporter activity [Term] id: CCO:F0001837 name: methyl-CpG binding namespace: molecular_function def: "Interacting selectively with a methylated cytosine/guanine dinucleotide." [GOC:jl, PMID:11746232] xref: GO:0008327 is_a: CCO:F0000031 ! nucleotide binding is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0001838 name: pattern recognition receptor activity namespace: molecular_function def: "Combining with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity. Such molecular patterns are sometimes associated with potential pathogens." [PMID:12507420, PMID:12925128, PMID:14523544] comment: Note that this term and its child terms are intended for gene products which are directly coupled to a signal transduction pathway; gene products which recognize polymeric structures such as polysaccharides or peptidoglycans in extracellular space, but are not directly coupled to signal transduction pathway, should use the term 'pattern binding ; GO:0001871' or its child terms. Note that many gene products that are called pattern recognition receptors in the literature have a broad range of potential ligands and also can be annotated to 'scavenger receptor activity ; GO:0005044'. synonym: "macrophage receptor activity" RELATED [] xref: GO:0008329 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0001839 name: protein tyrosine/threonine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: protein threonine/tyrosine phosphate + H2O = protein threonine/tyrosine + phosphate." [GOC:mah] xref: EC:3.1.3.- xref: GO:0008330 is_a: CCO:F0001086 ! phosphoprotein phosphatase activity [Term] id: CCO:F0001840 name: high voltage-gated calcium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a calcium ion by a high voltage-gated channel." [GOC:mtg_transport, ISBN:0815340729] synonym: "high voltage gated calcium channel activity" EXACT [] synonym: "high voltage-dependent calcium channel activity" EXACT [] xref: GO:0008331 is_a: CCO:F0001513 ! voltage-gated calcium channel activity [Term] id: CCO:F0001841 name: low voltage-gated calcium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a calcium ion by a low voltage-gated channel." [GOC:mtg_transport, ISBN:0815340729] synonym: "low voltage gated calcium channel activity" EXACT [] synonym: "low voltage-dependent calcium channel activity" EXACT [] synonym: "T-type channel" EXACT [] xref: GO:0008332 is_a: CCO:F0001513 ! voltage-gated calcium channel activity [Term] id: CCO:F0001842 name: gamma-butyrobetaine dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-trimethylammoniobutanoate + 2-oxoglutarate + O2 = 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2." [EC:1.14.11.1] subset: gosubset_prok synonym: "4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.1] synonym: "alpha-butyrobetaine hydroxylase activity" EXACT [EC:1.14.11.1] synonym: "butyrobetaine hydroxylase activity" EXACT [EC:1.14.11.1] synonym: "g-butyrobetaine dioxygenase activity" EXACT [] synonym: "gamma-BBH activity" EXACT [EC:1.14.11.1] synonym: "gamma-butyrobetaine hydroxylase activity" EXACT [EC:1.14.11.1] synonym: "gamma-butyrobetaine,2-oxoglutarate dioxygenase activity" EXACT [] xref: EC:1.14.11.1 xref: GO:0008336 xref: MetaCyc:1.14.11.1-RXN xref: Reactome:24086 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0001843 name: MAP kinase 1 activity namespace: molecular_function synonym: "ERK1" EXACT [] xref: EC:2.7.11.- xref: GO:0008338 is_a: CCO:F0001073 ! MAP kinase activity [Term] id: CCO:F0001844 name: MP kinase activity namespace: molecular_function synonym: "Mpk2" NARROW [] synonym: "p38" NARROW [] synonym: "SAPK2" NARROW [] xref: EC:2.7.11.- xref: GO:0008339 is_a: CCO:F0003465 ! SAP kinase activity [Term] id: CCO:F0001845 name: MAP kinase kinase kinase kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli." [GOC:bf, PMID:11790549] synonym: "MAPKKKK" EXACT [] xref: EC:2.7.11.- xref: GO:0008349 is_a: CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity [Term] id: CCO:F0001846 name: RNA polymerase subunit kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (DNA-directed RNA polymerase) = ADP + phospho-(DNA-directed RNA polymerase)." [EC:2.7.11.23] synonym: "[RNA-polymerase]-subunit kinase activity" EXACT [] synonym: "ATP:DNA-directed RNA polymerase phosphotransferase activity" EXACT [EC:2.7.11.23] synonym: "CTD kinase activity" NARROW [EC:2.7.11.23] synonym: "RNA-polymerase-subunit kinase activity" EXACT [EC:2.7.11.23] synonym: "STK9" RELATED [EC:2.7.11.23] xref: EC:2.7.11.23 xref: GO:0008353 xref: MetaCyc:[RNA-POLYMERASE\]-SUBUNIT-KINASE-RXN is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001847 name: bacterial binding namespace: molecular_function def: "Interacting selectively with any part of a bacterial cell." [GOC:jl] subset: goslim_pir subset: gosubset_prok synonym: "bacterium binding" EXACT [] synonym: "binding to bacterium" EXACT [] xref: GO:0008367 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0001848 name: Gram-negative bacterial binding namespace: molecular_function def: "Interacting selectively with any part of a Gram-negative bacterial cell." [GOC:jl] subset: gosubset_prok synonym: "binding to Gram-negative bacterium" EXACT [] synonym: "Gram-negative bacterium binding" EXACT [] xref: GO:0008368 is_a: CCO:F0001847 ! bacterial binding [Term] id: CCO:F0001849 name: sialyltransferase activity namespace: molecular_function def: "Catalysis of the formation of sialylglycoconjugates via transfer of the sialic acid group from CMP to one of several glycoconjugate acceptors." [GOC:jl, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: EC:2.4.99.- xref: GO:0008373 is_a: CCO:F0003332 ! transferase activity, transferring glycosyl groups [Term] id: CCO:F0001850 name: O-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0008374 xref: Reactome:1150 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0001851 name: acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to an oligosaccharide." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "GlcNAc transferase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0008375 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0001852 name: acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "GalNAc transferase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0008376 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0001853 name: galactosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:2.4.1.- xref: GO:0008378 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0001854 name: thioredoxin peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: thioredoxin + H2O2 = thioredoxin disulfide + H2O." [MetaCyc:RXN0-267] subset: gosubset_prok synonym: "thiol peroxidase activity" EXACT [] synonym: "TPx activity" EXACT [] synonym: "TrxPx activity" EXACT [] xref: EC:1.11.1.- xref: GO:0008379 xref: GO:0009031 xref: MetaCyc:RXN0-267 is_a: CCO:F0008212 ! peroxiredoxin activity [Term] id: CCO:F0001855 name: mechanically-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0008381 is_a: CCO:F0001492 ! ion channel activity is_a: CCO:F0004265 ! mechanically gated channel activity [Term] id: CCO:F0001856 name: IkappaB kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein." [EC:2.7.11.10] comment: Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB. The kinase is composed of alpha, beta and gamma subunits, of which the latter does not have kinase activity but is presumed to play a regulatory role. synonym: "ATP:IkappaB protein phosphotransferase activity" EXACT [EC:2.7.11.10] synonym: "CHUK" RELATED [EC:2.7.11.10] synonym: "ikappaB kinase activity" EXACT [EC:2.7.11.10] synonym: "IKBKA" RELATED [EC:2.7.11.10] synonym: "IKBKB" RELATED [EC:2.7.11.10] synonym: "IKK" RELATED [EC:2.7.11.10] synonym: "IKK-1" RELATED [EC:2.7.11.10] synonym: "IKK-2" RELATED [EC:2.7.11.10] synonym: "inhibitor of NF-kappaB kinase activity" EXACT [EC:2.7.11.10] synonym: "inhibitor of NFkappaB kinase activity" EXACT [EC:2.7.11.10] synonym: "STK12" RELATED [EC:2.7.11.10] synonym: "TANK-binding kinase 1 activity" NARROW [EC:2.7.11.10] synonym: "TBK1" RELATED [EC:2.7.11.10] xref: EC:2.7.11.10 xref: GO:0008384 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0001857 name: cholesterol monooxygenase (side-chain-cleaving) activity namespace: molecular_function def: "Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O." [EC:1.14.15.6] synonym: "C27-side chain cleavage enzyme" RELATED [EC:1.14.15.6] synonym: "cholesterol 20-22-desmolase activity" EXACT [EC:1.14.15.6] synonym: "cholesterol C(20-22) desmolase activity" EXACT [EC:1.14.15.6] synonym: "cholesterol C20-22 desmolase activity" EXACT [EC:1.14.15.6] synonym: "cholesterol desmolase activity" EXACT [EC:1.14.15.6] synonym: "cholesterol side-chain cleavage enzyme activity" RELATED [EC:1.14.15.6] synonym: "cholesterol side-chain-cleaving enzyme activity" RELATED [EC:1.14.15.6] synonym: "cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)" EXACT [EC:1.14.15.6] synonym: "Cyp11a1" NARROW [] synonym: "cytochrome P-450(scc) activity" NARROW [EC:1.14.15.6] synonym: "cytochrome P-450scc" RELATED [EC:1.14.15.6] synonym: "cytochrome p450(scc) activity" NARROW [EC:1.14.15.6] synonym: "cytochrome p450scc" RELATED [EC:1.14.15.6] synonym: "desmolase, steroid 20-22" EXACT [EC:1.14.15.6] synonym: "enzymes, cholesterol side-chain-cleaving" RELATED [EC:1.14.15.6] synonym: "steroid 20-22 desmolase activity" BROAD [EC:1.14.15.6] synonym: "steroid 20-22-lyase activity" BROAD [EC:1.14.15.6] xref: EC:1.14.15.6 xref: GO:0008386 xref: MetaCyc:1.14.15.6-RXN is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0001858 name: steroid 7-alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O." [GOC:mah] synonym: "cytochrome P450 CYP2A12" NARROW [] xref: GO:0008387 is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001859 name: testosterone 15-alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O." [GOC:ai] synonym: "cytochrome P450 CYP2A4" NARROW [] xref: GO:0008388 is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001860 name: coumarin 7-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+." [Reactome:163103] synonym: "cytochrome P450 CYP2A5" NARROW [] xref: GO:0008389 xref: Reactome:24222 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001861 name: testosterone 16-alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-alpha-hydroxytestosterone + H2O." [GOC:ai] synonym: "cytochrome P450 CYP2B10" NARROW [] synonym: "cytochrome P450 CYP2B9" NARROW [] synonym: "cytochrome P450 CYP2D10" NARROW [] synonym: "cytochrome P450 CYP2D11" NARROW [] synonym: "cytochrome P450 CYP2D9" NARROW [] xref: GO:0008390 is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001862 name: arachidonic acid monooxygenase activity namespace: molecular_function synonym: "cytochrome P450 CYP2B19" NARROW [] xref: GO:0008391 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001863 name: arachidonic acid epoxygenase activity namespace: molecular_function synonym: "cytochrome P450 CYP2J5" NARROW [] synonym: "cytochrome P450 CYP2J6" NARROW [] xref: GO:0008392 is_a: CCO:F0001862 ! arachidonic acid monooxygenase activity [Term] id: CCO:F0001864 name: fatty acid (omega-1)-hydroxylase activity namespace: molecular_function synonym: "cytochrome P450 CYP2E1" NARROW [] xref: GO:0008393 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001865 name: olfactory-specific steroid hydroxylase activity namespace: molecular_function synonym: "cytochrome P450 CYP2G1" NARROW [] xref: GO:0008394 is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001866 name: steroid hydroxylase activity namespace: molecular_function def: "Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0008395 is_a: CCO:F0000894 ! monooxygenase activity [Term] id: CCO:F0001867 name: oxysterol 7-alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O." [PMID:10882791] synonym: "cytochrome P450 CYP7B1" NARROW [] xref: GO:0008396 is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001868 name: sterol 12-alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O." [GOC:mah] synonym: "cytochrome P450 CYP8B1" NARROW [] xref: GO:0008397 is_a: CCO:F0001866 ! steroid hydroxylase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001869 name: sterol 14-demethylase activity namespace: molecular_function def: "Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O." [EC:1.14.13.70] subset: gosubset_prok synonym: "cytochrome P450 51 activity" NARROW [EC:1.14.13.70] synonym: "cytochrome P450 CYP51" NARROW [] synonym: "lanosterol 14-alpha-demethylase activity" NARROW [EC:1.14.13.70] synonym: "lanosterol 14-demethylase activity" NARROW [EC:1.14.13.70] synonym: "lanosterol 14alpha-demethylase activity" EXACT [EC:1.14.13.70] synonym: "obtusufoliol 14-demethylase activity" NARROW [EC:1.14.13.70] synonym: "sterol 14-alpha-demethylase activity" EXACT [EC:1.14.13.70] synonym: "sterol 14alpha-demethylase activity" EXACT [EC:1.14.13.70] synonym: "sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)" EXACT [EC:1.14.13.70] xref: EC:1.14.13.70 xref: GO:0008398 xref: MetaCyc:1.14.13.70-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen is_a: CCO:F0004997 ! demethylase activity [Term] id: CCO:F0001870 name: naphthalene hydroxylase activity namespace: molecular_function synonym: "cytochrome P450 CYP2F2" NARROW [] xref: GO:0008399 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001871 name: retinoic acid 4-hydroxylase activity namespace: molecular_function synonym: "cytochrome P450 CYP261" NARROW [] xref: GO:0008401 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001872 name: 25-hydroxycholecalciferol-24-hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of C-24 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycalciferol." [ISBN:0471331309 "Biochemical Pathways"] synonym: "25-hydroxyvitamin D3 24-hydroxylase activity" EXACT [] synonym: "cytochrome P450 CYP24" NARROW [] xref: GO:0008403 xref: GO:0030344 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0001873 name: arachidonic acid 14,15-epoxygenase activity namespace: molecular_function synonym: "cytochrome P450 CYP2C29" NARROW [] synonym: "cytochrome P450 CYP2C39" NARROW [] xref: GO:0008404 is_a: CCO:F0001862 ! arachidonic acid monooxygenase activity [Term] id: CCO:F0001874 name: arachidonic acid 11,12-epoxygenase activity namespace: molecular_function synonym: "cytochrome P450 CYP2C38" NARROW [] xref: GO:0008405 is_a: CCO:F0001862 ! arachidonic acid monooxygenase activity [Term] id: CCO:F0001875 name: 3'-5' exonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end." [GOC:ai] subset: gosubset_prok synonym: "3'-5'-exonuclease activity" EXACT [] xref: GO:0008408 is_a: CCO:F0000923 ! exonuclease activity [Term] id: CCO:F0001876 name: 5'-3' exonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end." [GOC:ai] subset: gosubset_prok xref: GO:0008409 is_a: CCO:F0000923 ! exonuclease activity [Term] id: CCO:F0001877 name: CoA-transferase activity namespace: molecular_function def: "Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor)." [GOC:jl] subset: gosubset_prok xref: EC:2.8.3.- xref: GO:0008410 is_a: CCO:F0003354 ! transferase activity, transferring sulfur-containing groups [Term] id: CCO:F0001878 name: 4-hydroxybutyrate CoA-transferase activity namespace: molecular_function def: "Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate." [GOC:jl] subset: gosubset_prok xref: GO:0008411 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0001879 name: 4-hydroxybenzoate octaprenyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: farnesylfarnesylgeranyl-PP + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate." [MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN] subset: gosubset_prok synonym: "4-HB polyprenyltransferase activity" EXACT [] synonym: "para-hydroxybenzoate transferase activity" EXACT [] synonym: "para-hydroxybenzoate-polyprenyl diphosphate transferase activity" EXACT [] synonym: "para-hydroxybenzoate:polyprenyltransferase activity" EXACT [] synonym: "PHB polyprenyl diphosphate transferase activity" EXACT [] xref: EC:2.5.1.- xref: GO:0000043 xref: GO:0008412 xref: GO:0048043 xref: GO:0048044 xref: MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN is_a: CCO:F0000268 ! polyprenyltransferase activity [Term] id: CCO:F0001880 name: 8-oxo-7,8-dihydroguanine triphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 8-oxo-7,8-dihydroguanine triphosphate = 8-oxo-7,8-dihydroguanine phosphate + diphosphate." [PMID:7782328] subset: gosubset_prok synonym: "7,8-dihydro-8-oxoguanine-triphosphatase activity" EXACT [] synonym: "8-oxo-GTPase activity" EXACT [] xref: EC:3.6.1.- xref: GO:0008413 is_a: CCO:F0003574 ! nucleoside-triphosphatase activity [Term] id: CCO:F0001881 name: CDP-alcohol phosphotransferase activity namespace: molecular_function def: "Catalysis of the transfer of a CDP-alcohol group from one compound to another." [GOC:jl] xref: GO:0008414 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0001882 name: acyltransferase activity namespace: molecular_function def: "Catalysis of the generalized reaction: acyl-carrier + reactant = acyl-reactant + carrier." [EC:2.3.1.-, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0008415 xref: Reactome:1091 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0001883 name: delta5-delta2,4-dienoyl-CoA isomerase activity namespace: molecular_function xref: EC:5.3.3.- xref: GO:0008416 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0001884 name: fucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] subset: gosubset_prok xref: EC:2.4.1.- xref: GO:0008417 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0001885 name: protein N-terminal asparagine amidohydrolase activity namespace: molecular_function xref: EC:3.5.1.- xref: GO:0008418 is_a: CCO:F0000542 ! asparaginase activity [Term] id: CCO:F0001886 name: RNA lariat debranching enzyme activity namespace: molecular_function xref: GO:0008419 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0001887 name: CTD phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phospho-(DNA-directed RNA polymerase) + H2O = (DNA-directed RNA polymerase) + phosphate." [EC:3.1.3.16] xref: GO:0008420 is_a: CCO:F0001087 ! protein serine/threonine phosphatase activity [Term] id: CCO:F0001888 name: long-chain-fatty-acyl-glutamate deacylase activity namespace: molecular_function def: "Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate." [EC:3.5.1.55] synonym: "long-chain acylglutamate amidase activity" EXACT [EC:3.5.1.55] synonym: "long-chain aminoacylase activity" EXACT [EC:3.5.1.55] synonym: "N-long-chain-fatty-acyl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.55] xref: EC:3.5.1.55 xref: GO:0008421 xref: MetaCyc:3.5.1.55-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0001889 name: beta-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose." [EC:3.2.1.21] subset: gosubset_prok synonym: "amygdalase activity" NARROW [EC:3.2.1.21] synonym: "amygdalinase" BROAD [EC:3.2.1.21] synonym: "arbutinase activity" EXACT [EC:3.2.1.21] synonym: "aryl-beta-glucosidase activity" EXACT [EC:3.2.1.21] synonym: "beta-1,6-glucosidase activity" EXACT [EC:3.2.1.21] synonym: "beta-D-glucosidase activity" EXACT [EC:3.2.1.21] synonym: "beta-D-glucoside glucohydrolase activity" EXACT [EC:3.2.1.21] synonym: "beta-glucoside glucohydrolase activity" EXACT [EC:3.2.1.21] synonym: "cellobiase activity" NARROW [EC:3.2.1.21] synonym: "elaterase activity" NARROW [EC:3.2.1.21] synonym: "emulsin" RELATED [EC:3.2.1.21] synonym: "gentiobiase activity" NARROW [EC:3.2.1.21] synonym: "gentobiase activity" NARROW [EC:3.2.1.21] synonym: "limarase activity" NARROW [EC:3.2.1.21] synonym: "p-nitrophenyl beta-glucosidase activity" EXACT [EC:3.2.1.21] synonym: "primeverosidase activity" NARROW [EC:3.2.1.21] synonym: "salicilinase activity" NARROW [EC:3.2.1.21] xref: EC:3.2.1.21 xref: GO:0008422 xref: MetaCyc:3.2.1.21-RXN is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0001890 name: bleomycin hydrolase activity namespace: molecular_function def: "Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred." [EC:3.4.22.40] subset: gosubset_prok synonym: "aminopeptidase C (Lactococcus lactis)" NARROW [EC:3.4.22.40] xref: EC:3.4.22.40 xref: GO:0008423 xref: MetaCyc:3.4.22.40-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0001891 name: glycoprotein 6-alpha-L-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-L-fucose + N4-{N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-N-acetyl-beta-D-glucosaminyl}asparagine = GDP + N4-{N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-[alpha-L-fucosyl-(1,6)]-N-acetyl-beta-D-glucosaminyl}asparagine." [EC:2.4.1.68] synonym: "FucT" RELATED [EC:2.4.1.68] synonym: "GDP-fucose--glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity" EXACT [EC:2.4.1.68] synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity" EXACT [EC:2.4.1.68] synonym: "GDP-L-fucose--glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] synonym: "GDPfucose-glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] synonym: "glycoprotein fucosyltransferase activity" BROAD [EC:2.4.1.68] synonym: "guanosine diphosphofucose--glycoprotein fucosyltransferase activity" EXACT [EC:2.4.1.68] xref: EC:2.4.1.68 xref: GO:0008424 xref: MetaCyc:2.4.1.68-RXN is_a: CCO:F0006273 ! alpha(1,6)-fucosyltransferase activity [Term] id: CCO:F0001892 name: 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:kd, PMID:9083048] subset: gosubset_prok synonym: "2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] synonym: "coenzyme Q biosynthesis methyltransferase activity" EXACT [] synonym: "coenzyme Q biosynthetic process methyltransferase activity" EXACT [] synonym: "ubiquinone biosynthesis methyltransferase activity" BROAD [] synonym: "ubiquinone biosynthetic process methyltransferase activity" BROAD [] xref: EC:2.1.1.- xref: GO:0008425 is_a: CCO:F0004484 ! quinone cofactor methyltransferase activity [Term] id: CCO:F0001893 name: protein kinase C inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein." [GOC:ai] synonym: "PKC inhibitor activity" EXACT [] xref: GO:0008426 is_a: CCO:F0004378 ! protein serine/threonine kinase inhibitor activity [Term] id: CCO:F0001894 name: calcium-dependent protein kinase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a calcium-dependent protein kinase." [GOC:mah] xref: GO:0008427 is_a: CCO:F0001216 ! protein kinase inhibitor activity [Term] id: CCO:F0001895 name: ribonuclease inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a ribonuclease, any enzyme that catalyzes the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:ai] subset: gosubset_prok xref: GO:0008428 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0001896 name: phosphatidylethanolamine binding namespace: molecular_function def: "Interacting selectively with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0008429 is_a: CCO:F0001666 ! phospholipid binding [Term] id: CCO:F0001897 name: selenium binding namespace: molecular_function def: "Interacting selectively with selenium (Se)." [GOC:ai] subset: gosubset_prok xref: GO:0008430 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0001898 name: vitamin E binding namespace: molecular_function def: "Interacting selectively with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant." [http://cancerweb.ncl.ac.uk/, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok synonym: "alpha-tocopherol binding" NARROW [] synonym: "tocopherol binding" EXACT [] xref: GO:0008431 is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0001899 name: JUN kinase binding namespace: molecular_function def: "Interacting selectively with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family." [GOC:jl] xref: GO:0008432 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0001900 name: vitamin D3 receptor activity namespace: molecular_function def: "Combining with vitamin D3, cholecalciferol, to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. synonym: "cholecaliferol receptor activity" EXACT [] xref: GO:0008434 is_a: CCO:F0001233 ! ligand-dependent nuclear receptor activity [Term] id: CCO:F0001901 name: thyrotropin-releasing hormone activity namespace: molecular_function xref: GO:0008437 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0001902 name: monophenol monooxygenase activator activity namespace: molecular_function def: "Increases the activity of the enzyme monophenol monooxygenase." [GOC:ai] synonym: "prophenol oxidase activator" RELATED [] xref: GO:0008439 is_a: CCO:F0000698 ! serine-type endopeptidase activity is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0001903 name: inositol trisphosphate 3-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate." [EC:2.7.1.127] synonym: "1D-myo-inositol-trisphosphate 3-kinase activity" EXACT [] synonym: "ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity" EXACT [EC:2.7.1.127] synonym: "inositol 1,4,5-trisphosphate 3-kinase activity" EXACT [] synonym: "inositol-trisphosphate 3-kinase activity" EXACT [] synonym: "ins(1,4,5)P(3) 3-kinase activity" EXACT [EC:2.7.1.127] synonym: "Ins(1,4,5)P3 3-kinase activity" EXACT [EC:2.7.1.127] synonym: "IP3 3-kinase activity" NARROW [EC:2.7.1.127] synonym: "IP3K activity" NARROW [EC:2.7.1.127] xref: EC:2.7.1.127 xref: GO:0008440 xref: MetaCyc:2.7.1.127-RXN is_a: CCO:F0008191 ! inositol trisphosphate kinase activity [Term] id: CCO:F0001904 name: 3'(2'),5'-bisphosphate nucleotidase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate." [EC:3.1.3.7] subset: gosubset_prok synonym: "3'(2'),5' bisphosphate nucleotidase activity" EXACT [] synonym: "3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity" EXACT [EC:3.1.3.7] synonym: "3'-phosphoadenylylsulfate 3'-phosphatase activity" EXACT [EC:3.1.3.7] synonym: "adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity" EXACT [EC:3.1.3.7] synonym: "DPNPase activity" EXACT [EC:3.1.3.7] synonym: "phosphoadenylate 3'-nucleotidase activity" EXACT [EC:3.1.3.7] xref: EC:3.1.3.7 xref: GO:0008441 xref: MetaCyc:3 xref: Reactome:24620 is_a: CCO:F0001795 ! nucleotidase activity [Term] id: CCO:F0001905 name: 3-hydroxyisobutyrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+." [EC:1.1.1.31] subset: gosubset_prok xref: EC:1.1.1.31 xref: GO:0008442 xref: MetaCyc:3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN xref: Reactome:24621 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001906 name: phosphofructokinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule." [GOC:jl] subset: gosubset_prok xref: EC:2.7.1.- xref: GO:0008443 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0001907 name: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-diacylglycerol + glycerol 3-phosphate = CMP + 3-(3-phosphatidyl)-glycerol 1-phosphate." [EC:2.7.8.5] subset: gosubset_prok synonym: "3-phosphatidyl-1'-glycerol-3'-phosphate synthase activity" EXACT [EC:2.7.8.5] synonym: "CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "glycerol 3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "glycerol phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "glycerophosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] synonym: "PGP synthase activity" EXACT [EC:2.7.8.5] synonym: "phosphatidylglycerol phosphate synthase activity" EXACT [EC:2.7.8.5] synonym: "phosphatidylglycerol phosphate synthetase activity" EXACT [EC:2.7.8.5] synonym: "phosphatidylglycerolphosphate synthase activity" EXACT [EC:2.7.8.5] synonym: "phosphatidylglycerophosphate synthase activity" EXACT [EC:2.7.8.5] synonym: "phosphatidylglycerophosphate synthetase activity" EXACT [EC:2.7.8.5] synonym: "sn-glycerol-3-phosphate phosphatidyltransferase activity" EXACT [EC:2.7.8.5] xref: EC:2.7.8.5 xref: GO:0008444 xref: MetaCyc:PHOSPHAGLYPSYN-RXN is_a: CCO:F0003607 ! CDP-alcohol phosphatidyltransferase activity [Term] id: CCO:F0001908 name: D-aspartate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2." [EC:1.4.3.1] synonym: "aspartic oxidase activity" EXACT [EC:1.4.3.1] synonym: "D-aspartate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.1] synonym: "D-aspartic oxidase activity" EXACT [EC:1.4.3.1] xref: EC:1.4.3.1 xref: GO:0008445 xref: MetaCyc:D-ASPARTATE-OXIDASE-RXN is_a: CCO:F0003017 ! aspartate oxidase activity [Term] id: CCO:F0001909 name: GDP-mannose 4,6-dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-mannose = GDP-4-dehydro-6-deoxy-D-mannose + H2O." [EC:4.2.1.47] subset: gosubset_prok synonym: "GDP-D-mannose 4,6-dehydratase activity" EXACT [EC:4.2.1.47] synonym: "GDP-D-mannose dehydratase activity" EXACT [EC:4.2.1.47] synonym: "GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)" EXACT [EC:4.2.1.47] synonym: "GDP-mannose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.47] synonym: "GDPmannose 4,6-dehydratase activity" EXACT [EC:4.2.1.47] synonym: "Gmd" RELATED [EC:4.2.1.47] synonym: "guanosine 5'-diphosphate-D-mannose oxidoreductase activity" EXACT [EC:4.2.1.47] synonym: "guanosine diphosphomannose 4,6-dehydratase activity" EXACT [EC:4.2.1.47] synonym: "guanosine diphosphomannose oxidoreductase activity" EXACT [EC:4.2.1.47] xref: EC:4.2.1.47 xref: GO:0008446 xref: MetaCyc:GDPMANDEHYDRA-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001910 name: L-ascorbate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 L-ascorbate + O2 = 2 dehydroascorbate + 2 H2O." [EC:1.10.3.3] synonym: "AA oxidase activity" EXACT [EC:1.10.3.3] synonym: "AAO" RELATED [EC:1.10.3.3] synonym: "ascorbase activity" EXACT [EC:1.10.3.3] synonym: "ascorbate dehydrogenase activity" EXACT [EC:1.10.3.3] synonym: "ascorbate oxidase activity" EXACT [EC:1.10.3.3] synonym: "ascorbic acid oxidase activity" EXACT [EC:1.10.3.3] synonym: "ascorbic oxidase activity" EXACT [EC:1.10.3.3] synonym: "L-ascorbate:O2 oxidoreductase activity" EXACT [EC:1.10.3.3] synonym: "L-ascorbate:oxygen oxidoreductase activity" EXACT [EC:1.10.3.3] synonym: "L-ascorbic acid oxidase activity" EXACT [EC:1.10.3.3] xref: EC:1.10.3.3 xref: GO:0008447 xref: MetaCyc:L-ASCORBATE-OXIDASE-RXN is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0001911 name: N-acetylglucosamine-6-phosphate deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate." [EC:3.5.1.25] subset: gosubset_prok synonym: "2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase activity" EXACT [EC:3.5.1.25] synonym: "acetylaminodeoxyglucosephosphate acetylhydrolase activity" EXACT [EC:3.5.1.25] synonym: "acetylglucosamine phosphate deacetylase activity" EXACT [EC:3.5.1.25] synonym: "N-acetyl-D-glucosamine-6-phosphate amidohydrolase activity" EXACT [EC:3.5.1.25] xref: EC:3.5.1.25 xref: GO:0008448 xref: MetaCyc:NAG6PDEACET-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0001912 name: N-acetylglucosamine-6-sulfatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate." [EC:3.1.6.14] subset: gosubset_prok synonym: "2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity" EXACT [EC:3.1.6.14] synonym: "acetylglucosamine 6-sulfatase activity" EXACT [EC:3.1.6.14] synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.14] synonym: "glucosamine-6-sulfatase activity" EXACT [EC:3.1.6.14] synonym: "N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity" EXACT [EC:3.1.6.14] synonym: "N-acetylglucosamine 6-sulfate sulfatase activity" EXACT [EC:3.1.6.14] synonym: "N-acetylglucosamine-6-sulphatase activity" EXACT [] synonym: "O,N-disulfate O-sulfohydrolase activity" EXACT [EC:3.1.6.14] xref: EC:3.1.6.14 xref: GO:0008449 xref: MetaCyc:3.1.6.14-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0001913 name: O-sialoglycoprotein endopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated." [EC:3.4.24.57] subset: gosubset_prok synonym: "glycophorin A proteinase activity" EXACT [EC:3.4.24.57] synonym: "glycoprotease activity" RELATED [EC:3.4.24.57] synonym: "glycoproteinase activity" EXACT [EC:3.4.24.57] synonym: "sialoglycoprotease activity" EXACT [EC:3.4.24.57] synonym: "sialoglycoproteinase activity" EXACT [EC:3.4.24.57] xref: EC:3.4.24.57 xref: GO:0008450 xref: MetaCyc:3.4.24.57-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0001914 name: X-Pro aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide." [EC:3.4.11.9] subset: gosubset_prok synonym: "aminoacylproline aminopeptidase activity" EXACT [EC:3.4.11.9] synonym: "aminopeptidase P" EXACT [] synonym: "proline aminopeptidase" BROAD [EC:3.4.11.9] synonym: "Xaa-Pro aminopeptidase activity" EXACT [] xref: EC:3.4.11.9 xref: GO:0008451 xref: MetaCyc:3.4.11.9-RXN is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0001915 name: RNA ligase activity namespace: molecular_function subset: gosubset_prok xref: EC:6.5.1.- xref: GO:0008452 is_a: CCO:F0003444 ! ligase activity, forming phosphoric ester bonds [Term] id: CCO:F0001916 name: alanine-glyoxylate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine." [EC:2.6.1.44] subset: gosubset_prok synonym: "AGT activity" EXACT [EC:2.6.1.44] synonym: "alanine--glyoxylate aminotransferase activity" EXACT [EC:2.6.1.44] synonym: "alanine-glyoxylate aminotransferase activity" EXACT [] synonym: "alanine-glyoxylic aminotransferase activity" EXACT [EC:2.6.1.44] synonym: "L-alanine-glycine transaminase activity" EXACT [EC:2.6.1.44] synonym: "L-alanine:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.44] xref: EC:2.6.1.44 xref: GO:0008453 xref: MetaCyc:ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0001917 name: alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R." [EC:2.4.1.145] synonym: "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.145] synonym: "alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [] synonym: "beta-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] synonym: "GnTIV activity" EXACT [EC:2.4.1.145] synonym: "N-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] synonym: "UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.145] synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.145] synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV" RELATED [EC:2.4.1.145] xref: EC:2.4.1.145 xref: GO:0008454 xref: MetaCyc:2.4.1.145-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0001918 name: alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R." [EC:2.4.1.143] synonym: "acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.143] synonym: "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [] synonym: "GnTII activity" EXACT [EC:2.4.1.143] synonym: "N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.143] synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.143] synonym: "UDP-GlcNAc:mannoside alpha-1-6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "UDP-GlcNAc:mannoside alpha1-6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1-2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1-2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta1-2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "uridine diphosphoacetylglucosamine-mannoside alpha-1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] synonym: "uridine diphosphoacetylglucosamine-mannoside alpha1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] xref: EC:2.4.1.143 xref: GO:0008455 xref: MetaCyc:2.4.1.143-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0001919 name: alpha-N-acetylgalactosaminidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides." [EC:3.2.1.49] synonym: "alpha-acetylgalactosaminidase activity" EXACT [EC:3.2.1.49] synonym: "alpha-galactosidase B activity" RELATED [EC:3.2.1.49] synonym: "alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity" EXACT [EC:3.2.1.49] synonym: "alpha-NAGA activity" EXACT [EC:3.2.1.49] synonym: "N-acetyl-alpha-D-galactosaminidase activity" EXACT [EC:3.2.1.49] synonym: "N-acetyl-alpha-galactosaminidase activity" EXACT [EC:3.2.1.49] xref: EC:3.2.1.49 xref: GO:0008456 xref: MetaCyc:3.2.1.49-RXN is_a: CCO:F0003024 ! hexosaminidase activity [Term] id: CCO:F0001920 name: beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide." [EC:2.4.1.163] synonym: "poly-N-acetyllactosamine extension enzyme activity" BROAD [EC:2.4.1.163] synonym: "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.163] synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.163] xref: EC:2.4.1.163 xref: GO:0008457 xref: MetaCyc:2.4.1.163-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0001921 name: carnitine O-octanoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine." [EC:2.3.1.137] synonym: "carnitine medium-chain acyltransferase activity" EXACT [EC:2.3.1.137] synonym: "easily solubilized mitochondrial carnitine palmitoyltransferase" NARROW [EC:2.3.1.137] synonym: "medium-chain/long-chain carnitine acyltransferase activity" EXACT [EC:2.3.1.137] synonym: "octanoyl-CoA:L-carnitine O-octanoyltransferase activity" EXACT [EC:2.3.1.137] synonym: "overt mitochondrial carnitine palmitoyltransferase" NARROW [EC:2.3.1.137] xref: EC:2.3.1.137 xref: GO:0008458 xref: MetaCyc:CARNITINE-O-OCTANOYLTRANSFERASE-RXN is_a: CCO:F0003129 ! carnitine O-acyltransferase activity is_a: CCO:F0003137 ! O-octanoyltransferase activity [Term] id: CCO:F0001922 name: chondroitin 6-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate." [EC:2.8.2.17] synonym: "3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase activity" EXACT [EC:2.8.2.17] synonym: "3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase activity" EXACT [EC:2.8.2.17] synonym: "chondroitin 6-O-sulfotransferase activity" EXACT [EC:2.8.2.17] synonym: "chondroitin 6-sulphotransferase activity" EXACT [] synonym: "terminal 6-sulfotransferase activity" EXACT [EC:2.8.2.17] xref: EC:2.8.2.17 xref: GO:0008459 xref: MetaCyc:CHONDROITIN-6-SULFOTRANSFERASE-RXN is_a: CCO:F0008396 ! chondroitin sulfotransferase activity [Term] id: CCO:F0001923 name: dTDP-glucose 4,6-dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O." [EC:4.2.1.46] subset: gosubset_prok synonym: "dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)" EXACT [EC:4.2.1.46] synonym: "dTDP-glucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.46] synonym: "dTDPglucose 4,6-dehydratase activity" EXACT [EC:4.2.1.46] synonym: "dTDPglucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.46] synonym: "TDP-glucose oxidoreductase activity" EXACT [EC:4.2.1.46] synonym: "thymidine diphosphoglucose oxidoreductase activity" EXACT [EC:4.2.1.46] xref: EC:4.2.1.46 xref: GO:0008460 xref: MetaCyc:DTDPGLUCDEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0001924 name: endopeptidase Clp activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs)." [EC:3.4.21.92] subset: gosubset_prok synonym: "ATP-dependent Clp protease" NARROW [EC:3.4.21.92] synonym: "caseinolytic protease activity" RELATED [EC:3.4.21.92] synonym: "Clp protease" NARROW [EC:3.4.21.92] synonym: "ClpP" RELATED [EC:3.4.21.92] synonym: "endopeptidase Ti activity" RELATED [EC:3.4.21.92] synonym: "protease Ti activity" RELATED [EC:3.4.21.92] xref: EC:3.4.21.92 xref: GO:0008462 xref: MetaCyc:3.4.21.92-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0001925 name: formylmethionine deformylase activity namespace: molecular_function def: "Catalysis of the reaction: N-formyl-L-methionine + H2O = formate + L-methionine." [EC:3.5.1.31] subset: gosubset_prok synonym: "N-formyl-L-methionine amidohydrolase activity" EXACT [EC:3.5.1.31] xref: EC:3.5.1.31 xref: GO:0008463 xref: MetaCyc:FORMYLMETHIONINE-DEFORMYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0001926 name: gamma-glutamyl hydrolase activity namespace: molecular_function def: "Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid." [EC:3.4.19.9] synonym: "carboxypeptidase G activity" BROAD [EC:3.4.19.9] synonym: "conjugase activity" RELATED [EC:3.4.19.9] synonym: "folate conjugase activity" RELATED [EC:3.4.19.9] synonym: "folic acid conjugase activity" EXACT [EC:3.4.19.9] synonym: "gamma-Glu-X carboxypeptidase activity" EXACT [EC:3.4.19.9] synonym: "lysosomal gamma-glutamyl carboxypeptidase activity" NARROW [EC:3.4.19.9] synonym: "poly(gamma-glutamic acid) endohydrolase activity" EXACT [EC:3.4.19.9] synonym: "poly(glutamic acid) hydrolase II" RELATED [EC:3.4.19.9] synonym: "polyglutamate hydrolase activity" EXACT [EC:3.4.19.9] synonym: "pteroyl-poly-alpha-glutamate hydrolase activity" NARROW [EC:3.4.19.9] synonym: "pteroyl-poly-gamma-glutamate hydrolase activity" EXACT [EC:3.4.19.9] synonym: "pteroylpoly-gamma-glutamyl hydrolase activity" EXACT [EC:3.4.19.9] xref: EC:3.4.19.9 xref: GO:0008464 xref: MetaCyc:3.4.19.9-RXN is_a: CCO:F0001792 ! omega peptidase activity [Term] id: CCO:F0001927 name: glycerate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+." [EC:1.1.1.29] subset: gosubset_prok synonym: "hydroxypyruvate dehydrogenase activity" BROAD [EC:1.1.1.29] xref: EC:1.1.1.29 xref: GO:0008465 xref: MetaCyc:GLYCERATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0001928 name: glycogenin glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin." [EC:2.4.1.186] synonym: "glycogenin activity" RELATED [EC:2.4.1.186] synonym: "priming glucosyltransferase activity" RELATED [EC:2.4.1.186] synonym: "UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.186] synonym: "UDP-glucose:glycogenin glucosyltransferase activity" EXACT [EC:2.4.1.186] xref: EC:2.4.1.186 xref: GO:0008466 xref: MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN xref: Reactome:24685 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0001930 name: histone-arginine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone-arginine = S-adenosyl-L-homocysteine + histone-N-methyl-arginine." [EC:2.1.1.125] synonym: "histone protein methylase activity" EXACT [EC:2.1.1.125] synonym: "histone protein methylase I" RELATED [EC:2.1.1.125] synonym: "nuclear protein (histone) N-methyltransferase activity" EXACT [EC:2.1.1.125] synonym: "protein methylase I activity" BROAD [EC:2.1.1.125] synonym: "S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity" EXACT [EC:2.1.1.125] synonym: "S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity" EXACT [EC:2.1.1.125] xref: EC:2.1.1.125 xref: GO:0008469 xref: GO:0016276 xref: MetaCyc:2.1.1.125-RXN is_a: CCO:F0003096 ! protein-arginine N-methyltransferase activity is_a: CCO:F0005616 ! histone methyltransferase activity [Term] id: CCO:F0001931 name: isovaleryl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF." [EC:1.3.99.10] subset: gosubset_prok synonym: "3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.99.10] synonym: "3-methylbutanoyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.3.99.10] synonym: "isovaleroyl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.10] synonym: "isovaleryl-coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.10] xref: EC:1.3.99.10 xref: GO:0008470 xref: MetaCyc:ISOVALERYL-COA-DEHYDROGENASE-RXN xref: Reactome:24705 is_a: CCO:F0000480 ! acyl-CoA dehydrogenase activity [Term] id: CCO:F0001932 name: laccase activity namespace: molecular_function def: "Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O." [EC:1.10.3.2] subset: gosubset_prok synonym: "benzenediol:oxygen oxidoreductase activity" EXACT [EC:1.10.3.2] synonym: "p-diphenol oxidase activity" EXACT [EC:1.10.3.2] synonym: "urishiol oxidase activity" RELATED [EC:1.10.3.2] synonym: "urushiol oxidase activity" EXACT [EC:1.10.3.2] xref: EC:1.10.3.2 xref: GO:0008471 xref: MetaCyc:LACCASE-RXN is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0001933 name: metallocarboxypeptidase D activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid." [EC:3.4.17.22] synonym: "carboxypeptidase D (cattle, human, mouse, rat)" RELATED [EC:3.4.17.22] synonym: "gp180 (duck)" RELATED [EC:3.4.17.22] xref: EC:3.4.17.22 xref: GO:0008472 xref: MetaCyc:3.4.17.22-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0001934 name: ornithine cyclodeaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-ornithine = L-proline + NH3." [EC:4.3.1.12] subset: gosubset_prok synonym: "L-ornithine ammonia-lyase (cyclizing)" EXACT [EC:4.3.1.12] synonym: "L-ornithine ammonia-lyase (cyclizing; L-proline-forming)" EXACT [EC:4.3.1.12] synonym: "OCD activity" EXACT [EC:4.3.1.12] synonym: "ornithine cyclase (deaminating) activity" EXACT [EC:4.3.1.12] synonym: "ornithine cyclase activity" EXACT [EC:4.3.1.12] xref: EC:4.3.1.12 xref: GO:0008473 xref: MetaCyc:ORNITHINE-CYCLODEAMINASE-RXN is_a: CCO:F0003406 ! ammonia-lyase activity is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0001935 name: palmitoyl-(protein) hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein." [EC:3.1.2.22] synonym: "palmitoyl-[protein] hydrolase" BROAD [EC:3.1.2.22] synonym: "palmitoyl-protein hydrolase activity" EXACT [] synonym: "palmitoyl-protein thioesterase activity" EXACT [] synonym: "palmitoyl-protein thiolesterase activity" EXACT [] xref: EC:3.1.2.22 xref: GO:0008474 xref: MetaCyc:3.1.2.22-RXN is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0001936 name: procollagen-lysine 5-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2." [EC:1.14.11.4] synonym: "collagen lysine hydroxylase activity" EXACT [EC:1.14.11.4] synonym: "lysine hydroxylase activity" BROAD [EC:1.14.11.4] synonym: "lysine,2-oxoglutarate 5-dioxygenase activity" BROAD [EC:1.14.11.4] synonym: "lysine-2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.4] synonym: "lysyl hydroxylase activity" BROAD [EC:1.14.11.4] synonym: "lysylprotocollagen dioxygenase activity" EXACT [EC:1.14.11.4] synonym: "peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity" EXACT [EC:1.14.11.4] synonym: "peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity" EXACT [EC:1.14.11.4] synonym: "procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.11.4] synonym: "procollagen-lysine,2-oxoglutarate 5-dioxygenase activity" EXACT [EC:1.14.11.4] synonym: "protocollagen lysine dioxygenase activity" EXACT [EC:1.14.11.4] synonym: "protocollagen lysine hydroxylase activity" EXACT [EC:1.14.11.4] synonym: "protocollagen lysyl hydroxylase activity" EXACT [EC:1.14.11.4] xref: EC:1.14.11.4 xref: GO:0008475 xref: MetaCyc:PROCOLLAGEN-LYSINE-5-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0001937 name: protein-tyrosine sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate." [EC:2.8.2.20] synonym: "3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity" EXACT [EC:2.8.2.20] synonym: "protein-tyrosine sulphotransferase activity" EXACT [] synonym: "tyrosylprotein sulfotransferase activity" EXACT [EC:2.8.2.20] xref: EC:2.8.2.20 xref: GO:0008476 xref: MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0001938 name: purine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose." [EC:3.2.2.1] subset: gosubset_prok synonym: "IAG-NH activity" RELATED [EC:3.2.2.1] synonym: "IAG-nucleoside hydrolase activity" RELATED [EC:3.2.2.1] synonym: "inosine-adenosine-guanosine preferring nucleoside hydrolase activity" NARROW [EC:3.2.2.1] synonym: "N-D-ribosylpurine ribohydrolase activity" EXACT [EC:3.2.2.1] synonym: "N-ribosyl purine ribohydrolase activity" EXACT [EC:3.2.2.1] synonym: "nucleosidase activity" BROAD [EC:3.2.2.1] synonym: "nucleosidase g activity" NARROW [EC:3.2.2.1] synonym: "nucleoside hydrolase activity" BROAD [EC:3.2.2.1] synonym: "purine beta-ribosidase activity" EXACT [EC:3.2.2.1] synonym: "purine nucleosidase reaction" EXACT [] synonym: "purine nucleoside hydrolase activity" EXACT [EC:3.2.2.1] synonym: "purine ribonucleosidase activity" EXACT [EC:3.2.2.1] synonym: "purine-nucleoside ribohydrolase activity" EXACT [EC:3.2.2.1] synonym: "purine-specific nucleoside N-ribohydrolase activity" EXACT [EC:3.2.2.1] synonym: "ribonucleoside hydrolase activity" EXACT [EC:3.2.2.1] xref: EC:3.2.2.1 xref: GO:0008477 xref: MetaCyc:PURINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0001939 name: pyridoxal kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate." [EC:2.7.1.35] subset: gosubset_prok synonym: "ATP:pyridoxal 5'-phosphotransferase activity" EXACT [EC:2.7.1.35] synonym: "pyridoxal 5-phosphate-kinase activity" EXACT [EC:2.7.1.35] synonym: "pyridoxal kinase (phosphorylating)" EXACT [EC:2.7.1.35] synonym: "pyridoxal phosphokinase activity" EXACT [EC:2.7.1.35] synonym: "pyridoxamine kinase activity" RELATED [EC:2.7.1.35] synonym: "pyridoxine kinase activity" RELATED [EC:2.7.1.35] synonym: "vitamin B(6) kinase activity" RELATED [EC:2.7.1.35] synonym: "vitamin B6 kinase activity" RELATED [EC:2.7.1.35] xref: EC:2.7.1.35 xref: GO:0008478 xref: MetaCyc:PYRIDOXKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0001940 name: queuine tRNA-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine." [EC:2.4.2.29] subset: gosubset_prok synonym: "[tRNA]-guanine:queuine tRNA-D-ribosyltransferase activity" EXACT [EC:2.4.2.29] synonym: "guanine insertion enzyme activity" RELATED [EC:2.4.2.29] synonym: "guanine, queuine-tRNA transglycosylase activity" EXACT [EC:2.4.2.29] synonym: "Q-insertase activity" EXACT [EC:2.4.2.29] synonym: "queuine transfer ribonucleate ribosyltransferase activity" EXACT [EC:2.4.2.29] synonym: "transfer ribonucleate glycosyltransferase activity" EXACT [EC:2.4.2.29] synonym: "tRNA guanine transglycosidase activity" EXACT [EC:2.4.2.29] synonym: "tRNA transglycosylase activity" EXACT [EC:2.4.2.29] synonym: "tRNA-guanine transglycosylase activity" EXACT [EC:2.4.2.29] xref: EC:2.4.2.29 xref: GO:0008479 xref: MetaCyc:QUEUOSINE-TRNA-RIBOSYLTRANSFERASE-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0001941 name: sarcosine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: sarcosine + acceptor + H2O = glycine + formaldehyde + reduced acceptor." [EC:1.5.99.1] subset: gosubset_prok synonym: "monomethylglycine dehydrogenase activity" EXACT [EC:1.5.99.1] synonym: "sarcosine N-demethylase activity" EXACT [EC:1.5.99.1] synonym: "sarcosine:(acceptor) oxidoreductase (demethylating)" EXACT [EC:1.5.99.1] synonym: "sarcosine:acceptor oxidoreductase (demethylating)" EXACT [EC:1.5.99.1] xref: EC:1.5.99.1 xref: GO:0008480 xref: MetaCyc:SARCOSINE-DEHYDROGENASE-RXN is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0001942 name: sphinganine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate." [EC:2.7.1.91] synonym: "ATP:sphinganine 1-phosphotransferase activity" EXACT [EC:2.7.1.91] synonym: "dihydrosphingosine kinase (phosphorylating)" EXACT [EC:2.7.1.91] synonym: "dihydrosphingosine kinase activity" EXACT [EC:2.7.1.91] synonym: "sphingosine kinase (phosphorylating)" EXACT [EC:2.7.1.91] synonym: "sphingosine kinase activity" RELATED [] xref: EC:2.7.1.91 xref: GO:0001728 xref: GO:0008481 xref: MetaCyc:SPHINGANINE-KINASE-RXN is_a: CCO:F0000204 ! lipid kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0001943 name: sulfite oxidase activity namespace: molecular_function def: "Catalysis of the reaction: SO3(2-) (sulfite) + O2 + H2O = SO4(2-) (sulfate) + H2O2." [EC:1.8.3.1] subset: gosubset_prok synonym: "sulfite:oxygen oxidoreductase activity" EXACT [EC:1.8.3.1] synonym: "sulphite oxidase activity" EXACT [] xref: EC:1.8.3.1 xref: GO:0008482 xref: MetaCyc:PWY-5326 xref: MetaCyc:SULFITE-OXIDASE-RXN is_a: CCO:F0003263 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor [Term] id: CCO:F0001944 name: transaminase activity namespace: molecular_function def: "Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "aminotransferase activity" EXACT [] xref: EC:2.6.1 xref: GO:0008483 is_a: CCO:F0003342 ! transferase activity, transferring nitrogenous groups [Term] id: CCO:F0001945 name: sulfuric ester hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2." [GOC:ai] subset: gosubset_prok synonym: "sulfatase activity" EXACT [] synonym: "sulphuric ester hydrolase activity" EXACT [] xref: EC:3.1.6 xref: GO:0008484 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0001946 name: diphosphoinositol-polyphosphate diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate." [EC:3.6.1.52] synonym: "diphospho-myo-inositol-polyphosphate diphosphohydrolase activity" EXACT [EC:3.6.1.52e] synonym: "diphosphoinositol polyphosphate phosphohydrolase activity" EXACT [] synonym: "diphosphoinositol-polyphosphate phosphohydrolase activity" EXACT [EC:3.6.1.52e] synonym: "DIPP activity" EXACT [EC:3.6.1.52e] xref: EC:3.6.1.52e xref: GO:0008486 xref: MetaCyc:3.6.1.52-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0001947 name: prenyl-dependent CAAX protease activity namespace: molecular_function xref: GO:0008487 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0001948 name: gamma-glutamyl carboxylase activity namespace: molecular_function subset: gosubset_prok xref: EC:4.1.1.- xref: GO:0008488 xref: Reactome:24735 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0001949 name: UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + glucosylceramide = lactosylceramide (galactosyl-beta-1,4-glucosylceramide) + UDP." [GOC:ai, PMID:9593693] synonym: "LacCer synthase activity" EXACT [] synonym: "lactosylceramide synthase activity" EXACT [] synonym: "UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity" EXACT [] xref: GO:0008489 is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0001950 name: arsenite secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:jl] subset: gosubset_prok synonym: "arsenite porter activity" RELATED [] xref: GO:0008490 xref: GO:0008491 is_a: CCO:F0002583 ! arsenite transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001951 name: tetracycline transporter activity namespace: molecular_function def: "Enables the directed movement of tetracycline into, out of, within or between cells. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)." [http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "tetracyclin transporter activity" EXACT [] xref: GO:0008493 is_a: CCO:F0005732 ! antibiotic transporter activity [Term] id: CCO:F0001952 name: translation activator activity namespace: molecular_function def: "Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide." [GOC:ai] xref: GO:0008494 is_a: CCO:F0001739 ! translation factor activity, nucleic acid binding [Term] id: CCO:F0001953 name: protoheme IX farnesyltransferase activity namespace: molecular_function subset: gosubset_prok synonym: "haem O synthase activity" EXACT [] synonym: "heme O synthase activity" EXACT [] synonym: "protohaem IX farnesyltransferase activity" EXACT [] xref: EC:2.5.1.- xref: GO:0008495 is_a: CCO:F0000732 ! farnesyltranstransferase activity [Term] id: CCO:F0001954 name: mannan endo-1,6-alpha-mannosidase activity namespace: molecular_function def: "Catalysis of the random hydrolysis of 1,6-alpha-D-mannosidic linkages in unbranched 1,6-mannans." [EC:3.2.1.101] synonym: "1,6-alpha-D-mannan mannanohydrolase activity" EXACT [EC:3.2.1.101] synonym: "1,6-beta-D-mannan mannanohydrolase activity" EXACT [EC:3.2.1.101] synonym: "endo-1,6-beta-mannanase activity" EXACT [EC:3.2.1.101] synonym: "endo-alpha-1->6-D-mannanase activity" EXACT [EC:3.2.1.101] synonym: "endo-alpha-D-mannosidase activity" EXACT [] synonym: "exo-1,6-beta-mannanase activity" EXACT [EC:3.2.1.101] synonym: "mannan endo-1,6-beta-mannosidase activity" EXACT [EC:3.2.1.101] xref: EC:3.2.1.101 xref: GO:0008496 xref: MetaCyc:3.2.1.101-RXN is_a: CCO:F0000944 ! alpha-mannosidase activity [Term] id: CCO:F0001955 name: UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP." [PMID:10212226] synonym: "beta-1,3-GalTase activity" BROAD [] synonym: "beta3Gal-Ts activity" BROAD [] synonym: "UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity" EXACT [] synonym: "UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity" EXACT [] xref: GO:0008499 is_a: CCO:F0005579 ! UDP-galactosyltransferase activity is_a: CCO:F0007345 ! beta-1,3-galactosyltransferase activity [Term] id: CCO:F0001956 name: melatonin receptor activity namespace: molecular_function def: "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0008502 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001957 name: benzodiazepine receptor activity namespace: molecular_function def: "Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity." [GOC:jl] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'chloride channel activity ; GO:0005254', 'GABA receptor activity ; GO:0016917' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'. xref: GO:0008503 is_a: CCO:F0004488 ! neurotransmitter receptor activity [Term] id: CCO:F0001958 name: monoamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of the membrane to the other." [ChEBI:25375, GOC:mah] xref: GO:0008504 xref: GO:0015201 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0001959 name: sucrose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in)." [TC:2.A.1.5.3] synonym: "hydrogen/sucrose transporter" RELATED [] synonym: "sucrose:proton symporter" EXACT [] xref: GO:0008506 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0001968 ! sucrose transmembrane transporter activity [Term] id: CCO:F0001960 name: sodium:iodide symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in)." [TC:2.A.21.5.1] synonym: "sodium/iodide symporter" EXACT [] xref: GO:0008507 is_a: CCO:F0002799 ! monovalent anion:sodium symporter activity [Term] id: CCO:F0001961 name: bile acid:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in)." [TC:2.A.28.-.-] synonym: "sodium/bile acid symporter" EXACT [] xref: GO:0008508 is_a: CCO:F0001571 ! organic acid:sodium symporter activity is_a: CCO:F0002602 ! bile acid transmembrane transporter activity [Term] id: CCO:F0001962 name: anion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other." [GOC:def, GOC:df, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "anion transporter activity" EXACT [] xref: GO:0008509 xref: Reactome:3160 is_a: CCO:F0002557 ! ion transmembrane transporter activity [Term] id: CCO:F0001963 name: sodium:bicarbonate symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in)." [TC:2.A.31.2.1] synonym: "sodium/bicarbonate cotransporter" EXACT [] synonym: "sodium:bicarbonate cotransporter activity" EXACT [] xref: GO:0008510 is_a: CCO:F0002584 ! bicarbonate transmembrane transporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0001964 name: sodium:potassium:chloride symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in)." [TC:2.A.30.1.1] synonym: "sodium/potassium/chloride symporter" EXACT [] xref: GO:0008511 is_a: CCO:F0002802 ! cation:chloride symporter activity [Term] id: CCO:F0001965 name: sulfate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in)." [TC:2.A.53.-.-] synonym: "sulfate/hydrogen symporter" EXACT [] synonym: "sulfate:proton symporter" EXACT [] synonym: "sulphate:hydrogen symporter activity" EXACT [] xref: GO:0008512 is_a: CCO:F0001811 ! secondary active sulfate transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0001966 name: secondary active organic cation transmembrane transporter activity namespace: molecular_function synonym: "organic cation porter activity" RELATED [] xref: GO:0008513 is_a: CCO:F0002580 ! organic cation transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001967 name: organic anion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai] subset: gosubset_prok xref: GO:0008514 is_a: CCO:F0001962 ! anion transmembrane transporter activity [Term] id: CCO:F0001968 name: sucrose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sucrose from one side of the membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "sucrose permease (PTS) activity" EXACT [] synonym: "sucrose permease activity" RELATED [] xref: GO:0008515 xref: GO:0019188 is_a: CCO:F0002631 ! disaccharide transmembrane transporter activity [Term] id: CCO:F0001969 name: hexose uniporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in)." [TC:2.A.1.1.5] xref: GO:0008516 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002626 ! hexose transmembrane transporter activity is_a: CCO:F0002741 ! uniporter activity [Term] id: CCO:F0001970 name: folic acid transporter activity namespace: molecular_function def: "Enables the directed movement of folic acid (pteroylglutamic acid) into, out of, within or between cells. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines." [GOC:ai] synonym: "folate transporter activity" EXACT [] synonym: "vitamin B9 transporter activity" EXACT [] synonym: "vitamin M transporter activity" EXACT [] xref: GO:0008517 is_a: CCO:F0008065 ! vitamin transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0001971 name: reduced folate carrier activity namespace: molecular_function def: "Catalysis of the transfer of reduced folate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] synonym: "reduced folate transporter" BROAD [] xref: GO:0008518 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0001972 name: ammonium transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0008519 is_a: CCO:F0002580 ! organic cation transmembrane transporter activity is_a: CCO:F0004309 ! inorganic cation transmembrane transporter activity [Term] id: CCO:F0001973 name: L-ascorbate:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ascorbate(out) + Na+(out) = ascorbate(in) + Na+(in)." [TC:2.A.40.6.1] synonym: "sodium-dependent L-ascorbic acid transporter" RELATED [] xref: GO:0008520 is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001974 name: acetyl-CoA transporter activity namespace: molecular_function def: "Enables the directed movement of acetyl-CoA into, out of, within or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis." [GOC:ai] xref: GO:0008521 is_a: CCO:F0008067 ! coenzyme transporter activity [Term] id: CCO:F0001975 name: sodium-dependent multivitamin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate." [TC:2.A.21.5.2] xref: GO:0008523 is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0001976 name: glucose 6-phosphate:phosphate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + phosphate(in) = glucose 6-phosphate(in) + phosphate(out)." [TC:2.A.1.-.-] xref: GO:0008524 is_a: CCO:F0002750 ! anion:anion antiporter activity is_a: CCO:F0002761 ! organophosphate:inorganic phosphate antiporter activity [Term] id: CCO:F0001977 name: phosphatidylcholine transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of phosphatidylcholine into, out of, within or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0008525 is_a: CCO:F0001671 ! phospholipid transporter activity [Term] id: CCO:F0001978 name: phosphatidylinositol transporter activity namespace: molecular_function def: "Enables the directed movement of phosphatidylinositol into, out of, within or between cells. Phosphatidylinositol refers to any glycophospholipids with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "phosphatidylinositol transfer" EXACT [] xref: GO:0008526 is_a: CCO:F0001671 ! phospholipid transporter activity [Term] id: CCO:F0001979 name: taste receptor activity namespace: molecular_function def: "Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste." [GOC:dph] synonym: "gustatory receptor" EXACT [] xref: GO:0008527 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0001980 name: peptide receptor activity, G-protein coupled namespace: molecular_function def: "Combining with an extracellular or intracellular peptide to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state." [GOC:dph, GOC:tb] synonym: "G protein coupled peptide receptor activity" EXACT [] synonym: "G-protein coupled peptide receptor activity" EXACT [] synonym: "G-protein-coupled peptide receptor activity" EXACT [] synonym: "peptide receptor activity, G protein coupled" EXACT [] xref: GO:0008528 is_a: CCO:F0000141 ! rhodopsin-like receptor activity is_a: CCO:F0000195 ! peptide receptor activity [Term] id: CCO:F0001981 name: riboflavin kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + riboflavin = ADP + FMN." [EC:2.7.1.26] subset: gosubset_prok synonym: "ATP:riboflavin 5'-phosphotransferase activity" EXACT [EC:2.7.1.26] synonym: "FK" RELATED [EC:2.7.1.26] synonym: "flavokinase activity" EXACT [EC:2.7.1.26] synonym: "riboflavin kinase (phosphorylating)" EXACT [EC:2.7.1.26] synonym: "riboflavine kinase activity" EXACT [EC:2.7.1.26] xref: EC:2.7.1.26 xref: GO:0008531 xref: MetaCyc:RIBOFLAVINKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0001982 name: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.149] synonym: "galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] synonym: "GnTE activity" EXACT [EC:2.4.1.149] synonym: "N-acetyllactosamine beta(1-3)N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] synonym: "poly-N-acetyllactosamine extension enzyme activity" BROAD [EC:2.4.1.149] synonym: "UDP-GlcNAc:Galbeta1->4GlcNAcbeta-rbeta1->3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] synonym: "UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] synonym: "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosamine beta-1,3-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.149] synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.149] xref: EC:2.4.1.149 xref: GO:0008532 xref: MetaCyc:2.4.1.149-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0001983 name: astacin activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'." [EC:3.4.24.21] subset: gosubset_prok synonym: "Astacus proteinase activity" EXACT [EC:3.4.24.21] synonym: "astacus proteinase activity" NARROW [EC:3.4.24.21] synonym: "crayfish small-molecule proteinase activity" NARROW [EC:3.4.24.21] xref: EC:3.4.24.21 xref: GO:0008533 xref: MetaCyc:3.4.24.21-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0001984 name: oxidized purine base lesion DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296] subset: gosubset_prok synonym: "2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity" EXACT [EC:3.2.2.23] synonym: "2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity" EXACT [EC:3.2.2.23] synonym: "8-oxoguanine DNA glycosylase activity" BROAD [] synonym: "bifunctional DNA glycosylase activity" BROAD [] synonym: "deoxyribonucleate glycosidase activity" EXACT [EC:3.2.2.23] synonym: "DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]" RELATED [EC:3.2.2.23] synonym: "DNA glycosylase/AP-lyase activity" BROAD [] synonym: "DNA glycosylase/beta-lyase activity" BROAD [] synonym: "DNA-formamidopyrimidine glycosylase activity" EXACT [] synonym: "fapy-DNA glycosylase activity" EXACT [EC:3.2.2.23] synonym: "Fapy-DNA glycosylase activity" EXACT [EC:3.2.2.23] synonym: "formamidopyrimidine-DNA glycosylase activity" EXACT [] synonym: "Fpg protein" RELATED [EC:3.2.2.23] synonym: "purine-specific oxidized base lesion DNA N-glycosylase activity" RELATED [] xref: EC:3.2.2.23 xref: GO:0003907 xref: GO:0008534 xref: MetaCyc:3.2.2.23-RXN xref: Reactome:24932 is_a: CCO:F0000095 ! oxidized base lesion DNA N-glycosylase activity is_a: CCO:F0000411 ! DNA-(apurinic or apyrimidinic site) lyase activity is_a: CCO:F0000917 ! endodeoxyribonuclease activity [Term] id: CCO:F0001985 name: Ran GTPase binding namespace: molecular_function def: "Interacting selectively with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly." [GOC:rn, PMID:12787777, PMID:14726649] synonym: "Ran protein binding" EXACT [] synonym: "Ran-binding protein" RELATED [] xref: GO:0008536 is_a: CCO:F0003512 ! Ras GTPase binding [Term] id: CCO:F0001986 name: proteasome activator activity namespace: molecular_function def: "Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis." [GOC:rn, PMID:10428771] synonym: "PA28" NARROW [] xref: GO:0008538 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0001987 name: proteasome inhibitor activity namespace: molecular_function synonym: "PI-31" NARROW [] xref: GO:0008539 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0001988 name: JUN kinase kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase." [GOC:bf, PMID:11057897, PMID:11790549] synonym: "JNKK" EXACT [] xref: EC:2.7.11.- xref: GO:0008545 is_a: CCO:F0001074 ! MAP kinase kinase activity [Term] id: CCO:F0001989 name: cadmium-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) = ADP + phosphate + Cd2+(out)." [EC:3.6.3.3] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (Cd2+-exporting)" EXACT [EC:3.6.3.3] synonym: "cadmium exporting ATPase activity" EXACT [] synonym: "cadmium-translocating P-type ATPase activity" RELATED [EC:3.6.3.3] synonym: "Cd(2+)-exporting ATPase activity" EXACT [EC:3.6.3.3] synonym: "Cd2+-exporting ATPase activity" EXACT [EC:3.6.3.3] synonym: "cd2+-exporting ATPase activity" EXACT [EC:3.6.3.3] xref: EC:3.6.3.3 xref: GO:0008551 xref: GO:0008561 xref: MetaCyc:3.6.3.3-RXN is_a: CCO:F0002566 ! cadmium ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0001990 name: hydrogen-exporting ATPase activity, phosphorylative mechanism namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out); by a phosphorylative mechanism." [EC:3.6.3.6] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (H+-exporting)" EXACT [EC:3.6.3.6] synonym: "H(+)-exporting ATPase activity" BROAD [EC:3.6.3.6] synonym: "H(+)-transporting ATPase activity" BROAD [EC:3.6.3.6] synonym: "H+-exporting ATPase activity" EXACT [EC:3.6.3.6] synonym: "H+-transporting ATPase" BROAD [EC:3.6.3.6] synonym: "hydrogen exporting ATPase activity, phosphorylative mechanism" EXACT [] synonym: "hydrogen-/sodium-translocating ATPase activity" RELATED [] synonym: "proton transport ATPase activity" RELATED [EC:3.6.3.6] synonym: "proton-exporting ATPase" RELATED [EC:3.6.3.6] synonym: "proton-translocating ATPase activity" EXACT [EC:3.6.3.6] synonym: "proton-translocating P-type ATPase activity" EXACT [EC:3.6.3.6] synonym: "yeast plasma membrane ATPase" NARROW [EC:3.6.3.6] synonym: "yeast plasma membrane H+-ATPase" NARROW [EC:3.6.3.6] xref: EC:3.6.3.6 xref: GO:0008553 xref: MetaCyc:3.6.3.6-RXN is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0001991 name: sodium-exporting ATPase activity, phosphorylative mechanism namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out); by a phosphorylative mechanism." [EC:3.6.3.7] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (Na+-exporting)" EXACT [EC:3.6.3.7] synonym: "hydrogen-/sodium-translocating ATPase activity" RELATED [] synonym: "Na(+)-exporting ATPase activity" EXACT [EC:3.6.3.7] synonym: "Na(+)-transporting ATPase activity" BROAD [EC:3.6.3.7] synonym: "Na+-exporting ATPase activity" EXACT [EC:3.6.3.7] synonym: "Na+-transporting ATPase activity" EXACT [EC:3.6.3.7] synonym: "sodium exporting ATPase activity, phosphorylative mechanism" EXACT [] synonym: "sodium transport ATPase activity" RELATED [EC:3.6.3.7] synonym: "sodium-exporting ATPase activity" EXACT [EC:3.6.3.7] synonym: "sodium-translocating P-type ATPase activity" RELATED [EC:3.6.3.7] xref: EC:3.6.3.7 xref: GO:0008554 xref: MetaCyc:3.6.3.7-RXN is_a: CCO:F0002562 ! sodium ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0001992 name: chloride-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cl-(out) = ADP + phosphate + Cl-(in)." [EC:3.6.3.11] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (Cl--importing)" EXACT [EC:3.6.3.11] synonym: "chloride ABC transporter" NARROW [] synonym: "chloride transporting ATPase activity" EXACT [] synonym: "chloride-motive ATPase activity" EXACT [EC:3.6.3.11] synonym: "chloride-translocating ATPase activity" EXACT [EC:3.6.3.11] synonym: "Cl(-)-transporting ATPase activity" EXACT [EC:3.6.3.11] synonym: "Cl--motive ATPase activity" EXACT [EC:3.6.3.11] synonym: "Cl--translocating ATPase activity" EXACT [EC:3.6.3.11] synonym: "Cl--transporting ATPase activity" EXACT [EC:3.6.3.11] synonym: "cl--transporting ATPase activity" EXACT [EC:3.6.3.11] xref: EC:3.6.3.11 xref: GO:0008555 xref: MetaCyc:3.6.3.11-RXN is_a: CCO:F0002586 ! chloride transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0001993 name: potassium-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in)." [EC:3.6.3.12] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (K+-importing)" EXACT [EC:3.6.3.12] synonym: "K(+)-importing ATPase activity" NARROW [EC:3.6.3.12] synonym: "K(+)-transporting ATPase activity" EXACT [EC:3.6.3.12] synonym: "K+-importing ATPase activity" EXACT [EC:3.6.3.12] synonym: "K+-translocating Kdp-ATPase activity" EXACT [EC:3.6.3.12] synonym: "K+-transporting ATPase activity" EXACT [] synonym: "k+-transporting ATPase activity" EXACT [EC:3.6.3.12] synonym: "multi-subunit K+-transport ATPase" NARROW [EC:3.6.3.12] synonym: "potassium ABC transporter" NARROW [] synonym: "potassium transporting ATPase activity" EXACT [] synonym: "potassium-importing ATPase activity" NARROW [EC:3.6.3.12] synonym: "potassium-uptake-ATPase activity" EXACT [] xref: EC:3.6.3.12 xref: GO:0008556 xref: GO:0015618 xref: MetaCyc:3.6.3.12-RXN is_a: CCO:F0002560 ! potassium ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0001994 name: guanine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in)." [EC:3.6.3.37] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (guanine-importing)" EXACT [EC:3.6.3.37] synonym: "guanine ABC transporter" NARROW [] xref: EC:3.6.3.37 xref: GO:0008558 xref: MetaCyc:3.6.3.37-RXN is_a: CCO:F0002679 ! guanine transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0001995 name: xenobiotic-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out)." [EC:3.6.3.44] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (steroid-exporting)" EXACT [EC:3.6.3.44] synonym: "ATP phosphohydrolase (xenobiotic-exporting)" EXACT [EC:3.6.3.44] synonym: "MDR protein" RELATED [EC:3.6.3.44] synonym: "multidrug resistance exporter" RELATED [] synonym: "multidrug-resistance protein" RELATED [] synonym: "P-glycoprotein" RELATED [] synonym: "PDR protein" RELATED [EC:3.6.3.44] synonym: "pleiotropic-drug-resistance protein" RELATED [EC:3.6.3.44] synonym: "steroid ABC transporter" NARROW [] synonym: "steroid-transporting ATPase activity" EXACT [] synonym: "xenobiotic ABC transporter" NARROW [] xref: EC:3.6.3.44 xref: GO:0005226 xref: GO:0008559 xref: GO:0008560 xref: MetaCyc:3.6.3.44-RXN is_a: CCO:F0002707 ! multidrug transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0001996 name: protein-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the concomitant secretion of proteins." [EC:3.6.3.50] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (protein-secreting)" EXACT [EC:3.6.3.50] synonym: "protein-secreting ATPase activity" EXACT [] xref: EC:3.6.3.50 xref: GO:0008564 xref: MetaCyc:3.6.3.50-RXN is_a: CCO:F0002869 ! protein-transmembrane transporting ATPase activity [Term] id: CCO:F0001997 name: protein transporter activity namespace: molecular_function def: "Enables the directed movement of proteins into, out of, within or between cells." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_goa subset: gosubset_prok synonym: "enzyme transporter activity" NARROW [] synonym: "holin" RELATED [] synonym: "protein carrier activity" EXACT [] synonym: "secretin (sensu Bacteria)" RELATED [] xref: GO:0008565 xref: GO:0015463 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0001998 name: mitochondrial protein-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex." [EC:3.6.3.51] comment: See also the cellular component term 'mitochondrial inner membrane presequence translocase complex ; GO:0005744'. Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (mitochondrial protein-importing) activity" EXACT [EC:3.6.3.51] xref: EC:3.6.3.51 xref: GO:0008566 xref: MetaCyc:3.6.3.51-RXN is_a: CCO:F0002869 ! protein-transmembrane transporting ATPase activity [Term] id: CCO:F0001999 name: microtubule-severing ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP." [EC:3.6.4.3, PMID:10910766] comment: See also the cellular component term 'katanin complex ; GO:0008352'. Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (tubulin-dimerizing)" EXACT [EC:3.6.4.3] synonym: "katanin activity" NARROW [EC:3.6.4.3] xref: EC:3.6.4.3 xref: GO:0008568 xref: MetaCyc:3.6.4.3-RXN is_a: CCO:F0005696 ! ATPase activity, coupled [Term] id: CCO:F0002000 name: minus-end-directed microtubule motor activity namespace: molecular_function def: "Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP (or GTP)." [EC:3.6.4.5, GOC:mah] synonym: "kinesin ATP phosphohydrolase (minus-end-directed)" EXACT [EC:3.6.4.5] synonym: "minus-end-directed kinesin ATPase activity" BROAD [] xref: EC:3.6.4.5 xref: GO:0008569 xref: MetaCyc:3.6.4.5-RXN is_a: CCO:F0000322 ! microtubule motor activity [Term] id: CCO:F0002001 name: plus-end-directed microtubule motor activity namespace: molecular_function def: "Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP (or GTP)." [EC:3.6.4.4] synonym: "kinesin activity" RELATED [EC:3.6.4.4] synonym: "kinesin ATP phosphohydrolase (plus-end-directed)" EXACT [EC:3.6.4.4] synonym: "plus-end-directed kinesin ATPase activity" BROAD [] xref: EC:3.6.4.4 xref: GO:0008574 xref: MetaCyc:3.6.4.4-RXN is_a: CCO:F0000322 ! microtubule motor activity [Term] id: CCO:F0002002 name: JUN kinase phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate." [GOC:mah] xref: EC:3.1.3.- xref: GO:0008579 is_a: CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity [Term] id: CCO:F0002003 name: ubiquitin-specific protease 5 activity namespace: molecular_function def: "Catalysis of the hydrolysis of the Gly76-Lys48 isopeptide bond of polyubiquitin." [ISBN:0120793709, MEROPS:c19p001] synonym: "ubiquitin isopeptidase T activity" EXACT [] xref: GO:0008581 is_a: CCO:F0000675 ! ubiquitin thiolesterase activity [Term] id: CCO:F0002004 name: calcium-dependent protein serine/threonine phosphatase regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase." [EC:3.1.3.16, GOC:ai] synonym: "calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity" NARROW [] xref: GO:0008597 xref: Reactome:25079 is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0002005 name: protein phosphatase type 1 regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme protein phosphatase type 1." [GOC:ai] synonym: "protein phosphatase type 1, intrinsic regulator activity" NARROW [] xref: GO:0008599 is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0002006 name: protein phosphatase type 2A regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme protein phosphatase type 2A." [GOC:ai] synonym: "protein phosphatase type 2A, intrinsic regulator activity" NARROW [] xref: GO:0008601 is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0002007 name: cAMP-dependent protein kinase regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme cAMP-dependent protein kinase." [GOC:ai] subset: gosubset_prok synonym: "3',5' cAMP-dependent protein kinase regulator activity" EXACT [] synonym: "3',5'-cAMP-dependent protein kinase regulator activity" EXACT [] synonym: "adenosine 3',5'-cyclophosphate-dependent protein kinase regulator activity" EXACT [] synonym: "cAMP-dependent protein kinase, intrinsic regulator activity" NARROW [] synonym: "cyclic AMP-dependent protein kinase regulator activity" EXACT [] xref: GO:0008603 is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0002008 name: protein kinase CK2 regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme protein kinase CK2." [GOC:ai] synonym: "casein kinase II, regulator" EXACT [] synonym: "protein kinase CK2, intrinsic regulator activity" NARROW [] xref: GO:0008605 is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0002009 name: phosphorylase kinase regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme phosphorylase kinase." [EC:2.7.11.19] synonym: "phosphorylase kinase, intrinsic regulator activity" NARROW [] xref: EC:2.7.1.- xref: GO:0008607 is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0002010 name: alkylglycerone-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion." [EC:2.5.1.26] subset: gosubset_prok synonym: "1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase activity" EXACT [EC:2.5.1.26] synonym: "alkyl DHAP synthetase activity" EXACT [EC:2.5.1.26] synonym: "alkyl-DHAP" RELATED [EC:2.5.1.26] synonym: "alkyl-DHAP synthase activity" EXACT [EC:2.5.1.26] synonym: "alkyldihydroxyacetone phosphate synthetase activity" EXACT [EC:2.5.1.26] synonym: "alkyldihydroxyacetonephosphate synthase activity" EXACT [EC:2.5.1.26] synonym: "DHAP-AT" RELATED [EC:2.5.1.26] synonym: "dihydroxyacetone-phosphate acyltransferase activity" EXACT [EC:2.5.1.26] xref: EC:2.5.1.26 xref: GO:0008609 xref: MetaCyc:ALKYLGLYCERONE-PHOSPHATE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0002011 name: diuretic hormone activity namespace: molecular_function xref: GO:0008613 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0002013 name: small protein activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:jl, GOC:mah] subset: goslim_pir synonym: "ubiquitin-like activating enzyme activity" NARROW [] xref: GO:0008641 xref: GO:0008642 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0002014 name: rRNA methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008649 is_a: CCO:F0001760 ! RNA methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0002015 name: rRNA (uridine-2'-O-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 2'-O atom of a uridine residue in an rRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0008650 is_a: CCO:F0003158 ! rRNA (uridine) methyltransferase activity [Term] id: CCO:F0002016 name: caspase activator activity namespace: molecular_function def: "Increases the rate of proteolysis catalyzed by a caspase." [GOC:mah] xref: GO:0008656 is_a: CCO:F0003186 ! apoptotic protease activator activity is_a: CCO:F0005788 ! caspase regulator activity [Term] id: CCO:F0002017 name: DNA gyrase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of DNA gyrase." [GOC:mah] xref: GO:0008657 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0002018 name: penicillin binding namespace: molecular_function def: "Interacting selectively with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:ai] subset: gosubset_prok xref: GO:0008658 is_a: CCO:F0001746 ! drug binding [Term] id: CCO:F0002020 name: 1-aminocyclopropane-1-carboxylate deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH3." [EC:3.5.99.7] comment: Note that this function was formerly EC:4.1.99.4. subset: gosubset_prok synonym: "1-aminocyclopropane carboxylic acid deaminase activity" EXACT [EC:3.5.99.7] synonym: "1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)" EXACT [EC:3.5.99.7] synonym: "1-aminocyclopropane-1-carboxylate endolyase (deaminating) activity" EXACT [EC:3.5.99.7] synonym: "ACC deaminase activity" EXACT [EC:3.5.99.7] xref: EC:3.5.99.7 xref: GO:0008660 xref: GO:0018806 xref: MetaCyc:4.1.99.4-RXN xref: UM-BBD_enzymeID:e0274 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0002021 name: 1-deoxy-D-xylulose-5-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2." [EC:2.2.1.7] subset: gosubset_prok synonym: "1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity" EXACT [] synonym: "1-deoxyxylulose-5-phosphate synthase activity" EXACT [] synonym: "DOXP synthase activity" EXACT [] synonym: "DXP-synthase activity" EXACT [] synonym: "pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)" EXACT [EC:2.2.1.7] xref: EC:2.2.1.7 xref: GO:0008661 xref: MetaCyc:DXS-RXN is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0002022 name: 1-phosphofructokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate." [EC:2.7.1.56] subset: gosubset_prok synonym: "1-phosphofructokinase (phosphorylating)" EXACT [EC:2.7.1.56] synonym: "ATP:D-fructose-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.56] synonym: "D-fructose-1-phosphate kinase activity" EXACT [EC:2.7.1.56] synonym: "fructose 1-phosphate kinase activity" EXACT [EC:2.7.1.56] synonym: "fructose-1-phosphate kinase activity" EXACT [EC:2.7.1.56] synonym: "phosphofructokinase 1" RELATED [EC:2.7.1.56] xref: EC:2.7.1.56 xref: GO:0008662 xref: MetaCyc:1PFRUCTPHOSN-RXN is_a: CCO:F0001906 ! phosphofructokinase activity [Term] id: CCO:F0002023 name: 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate." [EC:3.1.4.16] subset: gosubset_prok synonym: "2',3 '-cyclic AMP phosphodiesterase activity" EXACT [EC:3.1.4.16] synonym: "2',3'-cyclic AMP 2'-phosphohydrolase activity" EXACT [EC:3.1.4.16] synonym: "2',3'-cyclic nucleoside monophosphate phosphodiesterase" BROAD [EC:3.1.4.16] synonym: "2',3'-cyclic nucleotidase activity" EXACT [EC:3.1.4.16] synonym: "2',3'-cyclic nucleotide phosphohydrolase" BROAD [EC:3.1.4.16] synonym: "2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase activity" EXACT [EC:3.1.4.16] synonym: "2':3'-cyclic phosphodiesterase activity" EXACT [EC:3.1.4.16] synonym: "cyclic 2',3'-nucleotide 2'-phosphodiesterase activity" EXACT [EC:3.1.4.16] synonym: "cyclic 2',3'-nucleotide phosphodiesterase" BROAD [EC:3.1.4.16] synonym: "cyclic phosphodiesterase:3'-nucleotidase activity" EXACT [EC:3.1.4.16] synonym: "nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase activity" EXACT [EC:3.1.4.16] synonym: "ribonucleoside 2',3'-cyclic phosphate diesterase activity" EXACT [EC:3.1.4.16] xref: EC:3.1.4.16 xref: GO:0008663 xref: MetaCyc:CYCPHOSDIESTER-RXN is_a: CCO:F0000584 ! cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0002024 name: 2'-5'-RNA ligase activity namespace: molecular_function subset: gosubset_prok synonym: "2'-5' RNA ligase activity" EXACT [] xref: EC:6.5.1.- xref: GO:0008664 is_a: CCO:F0001915 ! RNA ligase activity [Term] id: CCO:F0002025 name: 2'-phosphotransferase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group from one compound to the 2' position of another." [GOC:jl, GOC:mah] subset: gosubset_prok xref: GO:0008665 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0002026 name: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate." [EC:2.3.1.117] subset: gosubset_prok synonym: "succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity" EXACT [EC:2.3.1.117] synonym: "succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity" EXACT [EC:2.3.1.117] synonym: "succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase activity" EXACT [EC:2.3.1.117] synonym: "tetrahydrodipicolinate N-succinyltransferase activity" EXACT [EC:2.3.1.117] synonym: "tetrahydrodipicolinate succinylase activity" EXACT [EC:2.3.1.117] synonym: "tetrahydrodipicolinate succinyltransferase activity" EXACT [EC:2.3.1.117] synonym: "tetrahydropicolinate succinylase activity" EXACT [EC:2.3.1.117] xref: EC:2.3.1.117 xref: GO:0008666 xref: MetaCyc:TETHYDPICSUCC-RXN is_a: CCO:F0003324 ! N-succinyltransferase activity [Term] id: CCO:F0002027 name: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydro-2,3-dihydroxybenzoate + NAD+ = 2,3-dihydroxybenzoate + NADH + H+." [EC:1.3.1.28] subset: gosubset_prok synonym: "2,3-DHB dehydrogenase activity" EXACT [EC:1.3.1.28] synonym: "2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.28] xref: EC:1.3.1.28 xref: GO:0008667 xref: MetaCyc:DHBDEHYD-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002029 name: 2,3-dihydroxy-phenylpropionate 1,2-dioxygenase activity namespace: molecular_function xref: EC:1.13.11.- xref: GO:0008669 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0002030 name: 2,4-dienoyl-CoA reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+." [EC:1.3.1.34] subset: gosubset_prok synonym: "4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.3.1.34] synonym: "4-enoyl-CoA reductase (NADPH) activity" EXACT [EC:1.3.1.34] synonym: "4-enoyl-CoA reductase (NADPH2)" EXACT [EC:1.3.1.34] synonym: "4-enoyl-CoA reductase activity" EXACT [EC:1.3.1.34] synonym: "trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity" EXACT [EC:1.3.1.34] xref: EC:1.3.1.34 xref: GO:0008670 xref: MetaCyc:DIENOYLCOAREDUCT-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002031 name: 2-dehydro-3-deoxygalactonokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-dehydro-3-deoxy-D-galactonate = ADP + 2-dehydro-3-deoxy-D-galactonate 6-phosphate." [EC:2.7.1.58] subset: gosubset_prok synonym: "2-keto-3-deoxy-galactonokinase activity" EXACT [EC:2.7.1.58] synonym: "2-keto-3-deoxygalactonate kinase (phosphorylating)" EXACT [EC:2.7.1.58] synonym: "2-keto-3-deoxygalactonokinase activity" EXACT [EC:2.7.1.58] synonym: "2-oxo-3-deoxygalactonate kinase activity" EXACT [EC:2.7.1.58] synonym: "ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase activity" EXACT [EC:2.7.1.58] xref: EC:2.7.1.58 xref: GO:0008671 xref: MetaCyc:DEHYDDEOXGALACTKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002032 name: 2-dehydro-3-deoxyglucarate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde." [EC:4.1.2.20] subset: gosubset_prok synonym: "2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.20] synonym: "2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase activity" EXACT [EC:4.1.2.20] synonym: "2-keto-3-deoxyglucarate aldolase activity" EXACT [EC:4.1.2.20] synonym: "alpha-keto-beta-deoxy-D-glucarate aldolase activity" EXACT [EC:4.1.2.20] xref: EC:4.1.2.20 xref: GO:0008672 xref: MetaCyc:KDGALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0002033 name: 2-dehydro-3-deoxygluconokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + beta-L-arabinose 1-phosphate." [EC:2.7.1.45] subset: gosubset_prok synonym: "2-keto-3-deoxy-D-gluconic acid kinase activity" EXACT [EC:2.7.1.45] synonym: "2-keto-3-deoxygluconate kinase activity" EXACT [EC:2.7.1.45] synonym: "2-keto-3-deoxygluconokinase (phosphorylating)" EXACT [EC:2.7.1.45] synonym: "2-keto-3-deoxygluconokinase activity" EXACT [EC:2.7.1.45] synonym: "3-deoxy-2-oxo-D-gluconate kinase activity" EXACT [EC:2.7.1.45] synonym: "ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.45] synonym: "KDG kinase activity" EXACT [EC:2.7.1.45] synonym: "ketodeoxygluconokinase activity" EXACT [EC:2.7.1.45] xref: EC:2.7.1.45 xref: GO:0008673 xref: MetaCyc:DEOXYGLUCONOKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002034 name: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate." [EC:4.1.2.21] subset: gosubset_prok synonym: "(KDPGal)aldolase activity" EXACT [EC:4.1.2.21] synonym: "2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)" EXACT [EC:4.1.2.21] synonym: "2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.21] synonym: "2-dehydro-3-deoxyphosphogalactonate aldolase activity" EXACT [] synonym: "2-keto-3-deoxy-6-phosphogalactonic acid aldolase activity" EXACT [EC:4.1.2.21] synonym: "2-keto-3-deoxy-6-phosphogalactonic aldolase activity" EXACT [EC:4.1.2.21] synonym: "2-oxo-3-deoxygalactonate 6-phosphate aldolase activity" EXACT [EC:4.1.2.21] synonym: "6-phospho-2-dehydro-3-deoxygalactonate aldolase activity" EXACT [EC:4.1.2.21] synonym: "6-phospho-2-keto-3-deoxygalactonate aldolase activity" EXACT [EC:4.1.2.21] synonym: "phospho-2-keto-3-deoxygalactonate aldolase activity" EXACT [EC:4.1.2.21] synonym: "phospho-2-keto-3-deoxygalactonic aldolase activity" EXACT [EC:4.1.2.21] xref: EC:4.1.2.21 xref: GO:0008674 xref: MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0002035 name: 2-dehydro-3-deoxy-phosphogluconate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate." [EC:4.1.2.14] subset: gosubset_prok synonym: "2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)" EXACT [EC:4.1.2.14] synonym: "2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.14] synonym: "2-keto-3-deoxy-6-phosphogluconate aldolase activity" EXACT [EC:4.1.2.14] synonym: "2-keto-3-deoxy-6-phosphogluconic aldolase activity" EXACT [EC:4.1.2.14] synonym: "2-keto-3-deoxygluconate-6-P-aldolase activity" EXACT [EC:4.1.2.14] synonym: "2-keto-3-deoxygluconate-6-phosphate aldolase activity" EXACT [EC:4.1.2.14] synonym: "2-oxo-3-deoxy-6-phosphogluconate aldolase activity" EXACT [EC:4.1.2.14] synonym: "6-phospho-2-keto-3-deoxygluconate aldolase activity" EXACT [EC:4.1.2.14] synonym: "KDPG aldolase activity" EXACT [EC:4.1.2.14] synonym: "KDPG-aldolase activity" EXACT [EC:4.1.2.14] synonym: "ODPG aldolase activity" EXACT [EC:4.1.2.14] synonym: "phospho-2-dehydro-3-deoxygluconate aldolase activity" EXACT [EC:4.1.2.14] synonym: "phospho-2-keto-3-deoxygluconate aldolase activity" EXACT [EC:4.1.2.14] synonym: "phospho-2-keto-3-deoxygluconic aldolase activity" EXACT [EC:4.1.2.14] xref: EC:4.1.2.14 xref: GO:0008675 xref: MetaCyc:KDPGALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0002036 name: 3-deoxy-8-phosphooctulonate synthase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate." [EC:2.5.1.55] comment: Note that this function was formerly EC:4.1.2.16. subset: gosubset_prok synonym: "2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.55] synonym: "2-dehydro-3-deoxy-phosphooctonate aldolase activity" EXACT [EC:2.5.1.55] synonym: "2-dehydro-3-deoxyphosphooctonate aldolase activity" EXACT [] synonym: "2-keto-3-deoxy-8-phosphooctonic synthetase activity" EXACT [EC:2.5.1.55] synonym: "3-deoxy-D-manno-octulosonate-8-phosphate synthase activity" EXACT [EC:2.5.1.55] synonym: "3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity" EXACT [EC:2.5.1.55] synonym: "3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity" EXACT [EC:2.5.1.55] synonym: "3-deoxyoctulosonic 8-phosphate synthetase activity" EXACT [EC:2.5.1.55] synonym: "KDO-8-P synthase activity" EXACT [EC:2.5.1.55] synonym: "KDO-8-phosphate synthetase activity" EXACT [EC:2.5.1.55] synonym: "KDOP synthase activity" EXACT [EC:2.5.1.55] synonym: "phospho-2-keto-3-deoxyoctonate aldolase activity" EXACT [EC:2.5.1.55] synonym: "phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)" EXACT [EC:2.5.1.55] xref: EC:2.5.1.55 xref: GO:0008676 xref: MetaCyc:KDO-8PSYNTH-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0002037 name: 2-dehydropantoate 2-reductase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+." [EC:1.1.1.169] subset: gosubset_prok synonym: "(R)-pantoate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.169] synonym: "2-ketopantoate reductase activity" EXACT [EC:1.1.1.169] synonym: "2-ketopantoic acid reductase activity" EXACT [EC:1.1.1.169] synonym: "2-oxopantoate reductase activity" EXACT [EC:1.1.1.169] synonym: "ketopantoate reductase activity" EXACT [EC:1.1.1.169] synonym: "ketopantoic acid reductase activity" EXACT [EC:1.1.1.169] synonym: "KPA reductase activity" EXACT [EC:1.1.1.169] xref: EC:1.1.1.169 xref: GO:0008677 xref: MetaCyc:2-DEHYDROPANTOATE-REDUCT-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002038 name: 2-deoxy-D-gluconate 3-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+." [EC:1.1.1.125] subset: gosubset_prok synonym: "2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.125] synonym: "2-deoxygluconate dehydrogenase activity" EXACT [EC:1.1.1.125] synonym: "2-keto-3-deoxygluconate oxidoreductase activity" EXACT [EC:1.1.1.125] xref: EC:1.1.1.125 xref: GO:0008678 xref: MetaCyc:KDUD-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002039 name: 2-hydroxy-3-oxopropionate reductase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+." [EC:1.1.1.60] subset: gosubset_prok synonym: "(R)-glycerate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.60] synonym: "tartronate semialdehyde reductase activity" EXACT [EC:1.1.1.60] xref: EC:1.1.1.60 xref: GO:0008679 xref: MetaCyc:TSA-REDUCT-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002040 name: 2-octaprenyl-6-methoxyphenol hydroxylase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008681 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0002041 name: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone." [MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN] xref: GO:0008682 xref: MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002042 name: 2-oxoglutarate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate = succinate semialdehyde + CO2." [EC:4.1.1.71] subset: gosubset_prok synonym: "2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)" EXACT [EC:4.1.1.71] synonym: "2-oxoglutarate carboxy-lyase activity" EXACT [EC:4.1.1.71] synonym: "alpha-ketoglutarate decarboxylase activity" EXACT [EC:4.1.1.71] synonym: "alpha-ketoglutaric decarboxylase activity" EXACT [EC:4.1.1.71] synonym: "pre-2-oxoglutarate decarboxylase activity" EXACT [EC:4.1.1.71] xref: EC:4.1.1.71 xref: GO:0008683 xref: MetaCyc:2-OXOGLUT-DECARBOX-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002043 name: 2-oxopent-4-enoate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O." [EC:4.2.1.80] subset: gosubset_prok synonym: "2-keto-4-pentenoate (vinylpyruvate)hydratase activity" EXACT [EC:4.2.1.80] synonym: "2-keto-4-pentenoate hydratase activity" EXACT [EC:4.2.1.80] synonym: "4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)" EXACT [EC:4.2.1.80] synonym: "4-hydroxy-2-oxopentanoate hydro-lyase activity" EXACT [EC:4.2.1.80] synonym: "OEH activity" EXACT [EC:4.2.1.80] xref: EC:4.2.1.80 xref: GO:0008684 xref: GO:0018821 xref: MetaCyc:2-OXOPENT-4-ENOATE-HYDRATASE-RXN xref: UM-BBD_enzymeID:e0078 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002044 name: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP." [EC:4.6.1.12, GOC:mlg] subset: gosubset_prok synonym: "2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)" EXACT [EC:4.6.1.12] synonym: "2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming)" EXACT [EC:4.6.1.12] synonym: "MECDP-synthase activity" EXACT [EC:4.6.1.12] synonym: "MECP synthase activity" EXACT [] xref: EC:4.6.1.12 xref: GO:0008685 is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0002045 name: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: ribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-phosphate + formate." [MetaCyc:DIOHBUTANONEPSYN-RXN] subset: gosubset_prok xref: EC:4.1.99.12 xref: GO:0008686 xref: MetaCyc:DIOHBUTANONEPSYN-RXN is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0002046 name: 3,4-dihydroxyphenylacetate 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O2 = 2-hydroxy-5-carboxymethylmuconate semialdehyde." [EC:1.13.11.15] subset: gosubset_prok synonym: "3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.15] synonym: "3,4-dihydroxyphenylacetic acid 2,3-dioxygenase activity" EXACT [EC:1.13.11.15] synonym: "homoprotocatechuate 2,3-dioxygenase activity" EXACT [EC:1.13.11.15] synonym: "HPC dioxygenase activity" EXACT [EC:1.13.11.15] xref: EC:1.13.11.15 xref: GO:0008687 xref: MetaCyc:1.13.11.15-RXN xref: UM-BBD_enzymeID:e0125 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0002047 name: 3-(3-hydroxy-phenyl)propionate hydroxylase activity namespace: molecular_function xref: EC:1.14.13.- xref: GO:0008688 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0002048 name: 3-demethylubiquinone-9 3-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9." [EC:2.1.1.64] subset: gosubset_prok synonym: "5-demethylubiquinone-9 methyltransferase activity" EXACT [EC:2.1.1.64] synonym: "OMHMB-methyltransferase activity" EXACT [EC:2.1.1.64] synonym: "S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase activity" EXACT [EC:2.1.1.64] synonym: "S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase activity" EXACT [EC:2.1.1.64] xref: EC:2.1.1.64 xref: GO:0008689 xref: MetaCyc:DHHB-METHYLTRANSFER-RXN is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0002049 name: 3-deoxy-manno-octulosonate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate." [EC:2.7.7.38] subset: gosubset_prok synonym: "2-keto-3-deoxyoctonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] synonym: "3-deoxy-D-manno-octulosonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] synonym: "CMP-2-keto-3-deoxyoctulosonic acid synthetase activity" EXACT [EC:2.7.7.38] synonym: "CMP-3-deoxy-D-manno-octulosonate diphosphorylase activity" EXACT [EC:2.7.7.38] synonym: "CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase activity" EXACT [EC:2.7.7.38] synonym: "CMP-3-deoxy-D-manno-octulosonate synthetase activity" EXACT [EC:2.7.7.38] synonym: "CMP-KDO synthetase activity" EXACT [EC:2.7.7.38] synonym: "CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] synonym: "CTP:3-deoxy-manno-octulosonate cytidylyltransferase activity" EXACT [] synonym: "CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity" EXACT [EC:2.7.7.38] synonym: "cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase activity" EXACT [EC:2.7.7.38] xref: EC:2.7.7.38 xref: GO:0008690 xref: MetaCyc:CPM-KDOSYNTH-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002050 name: 3-hydroxybutyryl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+." [EC:1.1.1.157] subset: gosubset_prok synonym: "(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.157] synonym: "beta-hydroxybutyryl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.157] synonym: "beta-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.157] synonym: "BHBD activity" EXACT [EC:1.1.1.157] synonym: "dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.157] synonym: "L(+)-3-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.157] synonym: "L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.157] xref: EC:1.1.1.157 xref: GO:0008691 xref: MetaCyc:3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002051 name: 3-hydroxybutyryl-CoA epimerase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA." [EC:5.1.2.3] subset: gosubset_prok synonym: "3-hydroxyacyl-CoA epimerase activity" EXACT [EC:5.1.2.3] synonym: "3-hydroxybutanoyl-CoA 3-epimerase activity" EXACT [EC:5.1.2.3] synonym: "3-hydroxybutyryl coenzyme A epimerase activity" EXACT [EC:5.1.2.3] xref: EC:5.1.2.3 xref: GO:0008692 xref: MetaCyc:OHBUTYRYL-COA-EPIM-RXN is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0002052 name: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O." [EC:4.2.1.60] subset: gosubset_prok synonym: "(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity" EXACT [EC:4.2.1.60] synonym: "3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity" EXACT [] synonym: "3-hydroxydecanoyl-ACP dehydratase activity" EXACT [] synonym: "3-hydroxydecanoyl-acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.60] synonym: "3-hydroxydecanoyl-acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.60] synonym: "3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.60] synonym: "beta-hydroxyacyl-ACP dehydrase activity" EXACT [EC:4.2.1.60] synonym: "beta-hydroxyacyl-acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.60] synonym: "beta-hydroxydecanoate dehydrase activity" EXACT [EC:4.2.1.60] synonym: "beta-hydroxydecanoyl thioester dehydrase activity" EXACT [EC:4.2.1.60] synonym: "beta-hydroxydecanoyl thiol ester dehydrase activity" EXACT [EC:4.2.1.60] synonym: "D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity" EXACT [EC:4.2.1.60] synonym: "D-3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.60] synonym: "FabA" RELATED [EC:4.2.1.60] synonym: "HDDase activity" EXACT [EC:4.2.1.60] xref: EC:4.2.1.60 xref: GO:0008693 xref: MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN is_a: CCO:F0004104 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [Term] id: CCO:F0002053 name: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2." [MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN] subset: gosubset_prok synonym: "3-octaprenyl-4-hydroxybenzoate decarboxylase activity" EXACT [] synonym: "3-polyprenyl 4-hydroxybenzoate decarboxylase activity" EXACT [] synonym: "3-polyprenyl-4-hydroxybenzoate carboxy-lyase activity" EXACT [] synonym: "polyprenyl p-hydroxybenzoate decarboxylase activity" EXACT [] synonym: "PPHB decarboxylase activity" EXACT [] synonym: "UbiD" RELATED [] synonym: "UbiX" RELATED [] xref: EC:4.1.1.- xref: GO:0008694 xref: GO:0019167 xref: MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002054 name: 3-phenylpropionate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol." [UM-BBD_enzymeID:e0307] synonym: "3-phenylpropanoate dioxygenase activity" EXACT [EC:1.14.12.19] synonym: "3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating) activity" EXACT [EC:1.14.12.19] synonym: "Hca dioxygenase activity" EXACT [EC:1.14.12.19] synonym: "HcaA1A2CD" RELATED [EC:1.14.12.19] xref: EC:1.14.12.19 xref: GO:0008695 xref: UM-BBD_enzymeID:e0307 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0002055 name: 4-amino-4-deoxychorismate lyase activity namespace: molecular_function def: "Catalysis of the reaction: 4-amino-4-deoxychorismate = p-aminobenzoate + pyruvate." [MetaCyc:ADCLY-RXN] comment: Note that the name 'para-amino benzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate. subset: gosubset_prok synonym: "4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)" EXACT [EC:4.1.3.38] synonym: "4-amino-4-deoxychorismate pyruvate-lyase activity" EXACT [EC:4.1.3.38] synonym: "ADC lyase activity" EXACT [EC:4.1.3.38] synonym: "aminodeoxychorismate lyase activity" EXACT [] synonym: "enzyme X activity" RELATED [EC:4.1.3.38] synonym: "p-aminobenzoate synthetase" RELATED [] synonym: "para-aminobenzoic acid (PABA) synthase" RELATED [] synonym: "para-aminobenzoic acid synthase" RELATED [] xref: EC:4.1.3.38 xref: GO:0008696 xref: MetaCyc:ADCLY-RXN is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0002056 name: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate." [EC:5.3.1.17] subset: gosubset_prok synonym: "4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.17] synonym: "4-deoxy-L-threo-5-hexulose uronate isomerase activity" EXACT [EC:5.3.1.17] synonym: "5-keto-4-deoxyuronate isomerase activity" EXACT [EC:5.3.1.17] xref: EC:5.3.1.17 xref: GO:0008697 xref: MetaCyc:5.3.1.17-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002057 name: 4-hydroxy-2-oxoglutarate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate." [EC:4.1.3.16] subset: gosubset_prok synonym: "2-keto-4-hydroxybutyrate aldolase activity" EXACT [EC:4.1.3.16] synonym: "2-keto-4-hydroxyglutarate aldolase activity" EXACT [EC:4.1.3.16] synonym: "2-keto-4-hydroxyglutaric aldolase activity" EXACT [EC:4.1.3.16] synonym: "2-oxo-4-hydroxyglutarate aldolase activity" EXACT [EC:4.1.3.16] synonym: "2-oxo-4-hydroxyglutaric aldolase activity" EXACT [EC:4.1.3.16] synonym: "4-hydroxy-2-ketoglutarate aldolase activity" EXACT [EC:4.1.3.16] synonym: "4-hydroxy-2-ketoglutaric aldolase activity" EXACT [EC:4.1.3.16] synonym: "4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)" EXACT [EC:4.1.3.16] synonym: "4-hydroxy-2-oxoglutarate glyoxylate-lyase activity" EXACT [EC:4.1.3.16] synonym: "DL-4-hydroxy-2-ketoglutarate aldolase activity" EXACT [EC:4.1.3.16] synonym: "hydroxyketoglutarate aldolase activity" EXACT [EC:4.1.3.16] synonym: "hydroxyketoglutaric aldolase activity" EXACT [EC:4.1.3.16] synonym: "KHG-aldolase activity" EXACT [EC:4.1.3.16] xref: EC:4.1.3.16 xref: GO:0008700 xref: MetaCyc:4OH2OXOGLUTARALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0002058 name: 4-hydroxy-2-oxovalerate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = pyruvate + acetaldehyde." [EC:4.1.3.39] synonym: "4-hydroxy-2-ketovalerate aldolase activity" EXACT [EC:4.1.3.39] synonym: "4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity" EXACT [EC:4.1.3.39] synonym: "4-hydroxy-2-oxopentanoate pyruvate-lyase activity" EXACT [EC:4.1.3.39] synonym: "4-hydroxy-2-oxovalerate pyruvate-lyase activity" EXACT [EC:4.1.3.39] synonym: "DmpG" RELATED [EC:4.1.3.39] synonym: "HOA" RELATED [EC:4.1.3.39] xref: EC:4.1.3.39 xref: GO:0008701 xref: GO:0018804 xref: UM-BBD_enzymeID:e0077 is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0002059 name: 5-amino-6-(5-phosphoribosylamino)uracil reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+." [EC:1.1.1.193] subset: gosubset_prok synonym: "5-amino-6-(5'-phosphoribosylamino)uracil reductase activity" EXACT [] synonym: "5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase activity" EXACT [EC:1.1.1.193] synonym: "aminodioxyphosphoribosylaminopyrimidine reductase activity" EXACT [EC:1.1.1.193] xref: EC:1.1.1.193 xref: GO:0008703 xref: MetaCyc:RIBOFLAVINSYNREDUC-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002060 name: 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate." [EC:5.3.3.10] subset: gosubset_prok synonym: "2-hydroxyhepta-2,4-diene-1,7-dioate isomerase" RELATED [] synonym: "5-carboxymethyl-2-hydroxymuconate D-isomerase activity" EXACT [] synonym: "5-carboxymethyl-2-hydroxymuconate delta2,Delta4-2-oxo,Delta3-isomerase activity" EXACT [EC:5.3.3.10] synonym: "5-carboxymethyl-2-hydroxymuconic acid isomerase activity" EXACT [EC:5.3.3.10] synonym: "CHM isomerase activity" EXACT [EC:5.3.3.10] synonym: "HHDD isomerase activity" EXACT [] synonym: "hpaG-1" RELATED [] synonym: "hpaG1" RELATED [] xref: EC:5.3.3.10 xref: GO:0008704 xref: GO:0018843 xref: MetaCyc:5.3.3.10-RXN xref: UM-BBD_enzymeID:e0135 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0002061 name: methionine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 5-methyltetrahydrofolate + L-homocysteine = tetrahydrofolate + L-methionine." [EC:2.1.1.13] subset: gosubset_prok synonym: "5-methyltetrahydrofolate--homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "5-methyltetrahydrofolate--homocysteine transmethylase activity" EXACT [EC:2.1.1.13] synonym: "5-methyltetrahydrofolate-homocysteine S-methyltransferase activity" EXACT [] synonym: "5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "cobalamin-dependent methionine synthase activity" EXACT [EC:2.1.1.13] synonym: "MetH" RELATED [EC:2.1.1.13] synonym: "methionine synthase (cobalamin-dependent) activity" EXACT [EC:2.1.1.13] synonym: "methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "N(5)-methyltetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity" EXACT [EC:2.1.1.13] synonym: "N-methyltetrahydrofolate:L-homocysteine methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "N5-methyltetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity" EXACT [EC:2.1.1.13] synonym: "tetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "tetrahydropteroylglutamate methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "tetrahydropteroylglutamic methyltransferase activity" EXACT [EC:2.1.1.13] synonym: "vitamin B12 methyltransferase activity" EXACT [EC:2.1.1.13] xref: EC:2.1.1.13 xref: GO:0008705 xref: MetaCyc:HOMOCYSMETB12-RXN xref: Reactome:25894 is_a: CCO:F0001759 ! S-methyltransferase activity is_a: CCO:F0005620 ! 5-methyltetrahydrofolate-dependent methyltransferase activity [Term] id: CCO:F0002062 name: 6-phospho-beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose." [EC:3.2.1.86] subset: gosubset_prok synonym: "6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase activity" EXACT [EC:3.2.1.86] synonym: "phospho-beta-glucosidase A" RELATED [EC:3.2.1.86] synonym: "phospho-beta-glucosidase activity" EXACT [EC:3.2.1.86] synonym: "phosphocellobiase activity" EXACT [EC:3.2.1.86] xref: EC:3.2.1.86 xref: GO:0008706 xref: MetaCyc:6-PHOSPHO-BETA-GLUCOSIDASE-RXN is_a: CCO:F0001889 ! beta-glucosidase activity [Term] id: CCO:F0002063 name: 4-phytase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate." [EC:3.1.3.26] subset: gosubset_prok synonym: "6-phytase (name based on 1L-numbering system and not 1D-numbering)" BROAD [EC:3.1.3.26] synonym: "6-phytase activity" EXACT [] synonym: "myo-inositol-hexakisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.26] synonym: "phytase activity" BROAD [EC:3.1.3.26] synonym: "phytate 6-phosphatase activity" EXACT [EC:3.1.3.26] xref: EC:3.1.3.26 xref: GO:0008707 xref: MetaCyc:6-PHYT-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0002064 name: 7-alpha-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD+ = 3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + NADH + H+." [EC:1.1.1.159] subset: gosubset_prok synonym: "7alpha-HSDH" RELATED [EC:1.1.1.159] synonym: "7alpha-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.159] synonym: "7alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.159] synonym: "7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity" EXACT [EC:1.1.1.159] xref: EC:1.1.1.159 xref: GO:0008709 xref: MetaCyc:7-ALPHA-HYDROXYSTEROID-DEH-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002065 name: 8-amino-7-oxononanoate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 6-carboxyhexanoyl-CoA + L-alanine = 8-amino-7-oxononanoate + CoA + CO2." [EC:2.3.1.47] subset: gosubset_prok synonym: "6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating)" EXACT [EC:2.3.1.47] synonym: "7-KAP synthetase activity" EXACT [EC:2.3.1.47] synonym: "7-keto-8-amino-pelargonic acid synthetase activity" EXACT [EC:2.3.1.47] synonym: "7-keto-8-aminopelargonic acid synthetase activity" EXACT [EC:2.3.1.47] synonym: "7-keto-8-aminopelargonic synthetase activity" EXACT [EC:2.3.1.47] synonym: "8-amino-7-ketopelargonate synthase activity" EXACT [EC:2.3.1.47] synonym: "8-amino-7-oxopelargonate synthase activity" EXACT [EC:2.3.1.47] synonym: "AONS activity" EXACT [EC:2.3.1.47] xref: EC:2.3.1.47 xref: GO:0008710 xref: MetaCyc:7KAPSYN-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0002066 name: ADP-glyceromanno-heptose 6-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose." [EC:5.1.3.20] subset: gosubset_prok synonym: "ADP-L-glycero-D-manno-heptose 6-epimerase activity" EXACT [EC:5.1.3.20] synonym: "ADPglyceromanno-heptose 6-epimerase activity" EXACT [EC:5.1.3.20] xref: EC:5.1.3.20 xref: GO:0008712 xref: MetaCyc:5.1.3.20-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0002067 name: ADP-heptose-lipopolysaccharide heptosyltransferase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008713 is_a: CCO:F0002256 ! lipopolysaccharide heptosyltransferase activity [Term] id: CCO:F0002068 name: AMP nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: AMP + H2O = adenine + D-ribose 5-phosphate." [EC:3.2.2.4] subset: gosubset_prok synonym: "adenosine monophosphate nucleosidase activity" EXACT [EC:3.2.2.4] synonym: "adenylate nucleosidase activity" EXACT [EC:3.2.2.4] synonym: "AMP phosphoribohydrolase activity" EXACT [EC:3.2.2.4] xref: EC:3.2.2.4 xref: GO:0008714 xref: MetaCyc:AMP-NUCLEOSID-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0002069 name: CDP-diacylglycerol diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-diacylglycerol + H2O = CMP + phosphatidate." [EC:3.6.1.26] subset: gosubset_prok synonym: "CDP diacylglycerol hydrolase activity" EXACT [EC:3.6.1.26] synonym: "CDP-diacylglycerol phosphatidylhydrolase activity" EXACT [EC:3.6.1.26] synonym: "CDP-diacylglycerol pyrophosphatase activity" EXACT [] synonym: "cytidine diphosphodiacylglycerol pyrophosphatase activity" EXACT [EC:3.6.1.26] xref: EC:3.6.1.26 xref: GO:0008715 xref: MetaCyc:CDPDIGLYPYPHOSPHA-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0002070 name: D-alanine-D-alanine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine." [EC:6.3.2.4] subset: gosubset_prok synonym: "alanine:alanine ligase (ADP-forming) activity" EXACT [EC:6.3.2.4] synonym: "alanylalanine synthetase activity" EXACT [EC:6.3.2.4] synonym: "D-Ala-D-Ala synthetase activity" EXACT [EC:6.3.2.4] synonym: "D-alanine:D-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.4] synonym: "D-alanyl-D-alanine synthetase activity" EXACT [EC:6.3.2.4] synonym: "D-alanylalanine synthetase activity" EXACT [EC:6.3.2.4] xref: EC:6.3.2.4 xref: GO:0008716 xref: MetaCyc:DALADALALIG-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0002071 name: D-alanyl-D-alanine endopeptidase activity namespace: molecular_function subset: gosubset_prok synonym: "penicillin-binding protein 7" NARROW [] synonym: "penicillin-binding protein 8" NARROW [] xref: EC:3.4.99.- xref: GO:0008717 is_a: CCO:F0000644 ! endopeptidase activity [Term] id: CCO:F0002072 name: D-amino-acid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor." [EC:1.4.99.1] subset: gosubset_prok synonym: "D-amino-acid:(acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.99.1] synonym: "D-amino-acid:acceptor oxidoreductase (deaminating)" EXACT [EC:1.4.99.1] xref: EC:1.4.99.1 xref: GO:0008718 xref: MetaCyc:DAADEHYDROG-RXN is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0002073 name: dihydroneopterin triphosphate 2'-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate." [MetaCyc:H2NTPEPIM-RXN] subset: gosubset_prok synonym: "D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase activity" EXACT [] xref: EC:5.-.-.- xref: GO:0008719 xref: MetaCyc:H2NTPEPIM-RXN is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0002074 name: D-lactate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-lactate + NAD+ = pyruvate + NADH + H+." [EC:1.1.1.28] subset: gosubset_prok synonym: "D-lactic acid dehydrogenase activity" EXACT [EC:1.1.1.28] synonym: "D-lactic dehydrogenase activity" EXACT [EC:1.1.1.28] xref: EC:1.1.1.28 xref: GO:0008720 xref: MetaCyc:DLACTDEHYDROGNAD-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002075 name: D-serine ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: D-serine = pyruvate + NH3." [EC:4.3.1.18] comment: Note that this function was formerly EC:4.3.1.14. subset: gosubset_prok synonym: "D-hydroxy amino acid dehydratase activity" BROAD [EC:4.3.1.18] synonym: "D-hydroxyaminoacid dehydratase activity" EXACT [EC:4.3.1.18] synonym: "D-serine ammonia-lyase (pyruvate-forming)" EXACT [EC:4.3.1.18] synonym: "D-serine deaminase activity" EXACT [EC:4.3.1.18] synonym: "D-serine dehydrase activity" EXACT [EC:4.3.1.18] synonym: "D-serine dehydratase (deaminating) activity" EXACT [EC:4.3.1.18] synonym: "D-serine dehydratase activity" EXACT [EC:4.3.1.18] synonym: "D-serine hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.18] synonym: "D-serine hydrolase activity" EXACT [EC:4.3.1.18] xref: EC:4.3.1.18 xref: GO:0008721 xref: MetaCyc:DSERDEAM-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0002076 name: DNA-3-methyladenine glycosylase I activity namespace: molecular_function def: "Catalysis of the hydrolysis of alkylated DNA; only recognizes and removes the alkylated base 3-methyladenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site." [EC:3.2.2.20, GOC:elh, PMID:10872450, PMID:9224623] subset: gosubset_prok synonym: "3-methyladenine DNA glycosylase I" RELATED [EC:3.2.2.20] synonym: "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)" BROAD [EC:3.2.2.20] synonym: "deoxyribonucleate 3-methyladenine glycosidase I" RELATED [EC:3.2.2.20] synonym: "DNA glycosidase I activity" RELATED [EC:3.2.2.20] synonym: "DNA-3-methyladenine glycosidase I activity" EXACT [EC:3.2.2.20] xref: EC:3.2.2.20 xref: GO:0008725 xref: MetaCyc:3.2.2.20-RXN is_a: CCO:F0000410 ! alkylbase DNA N-glycosylase activity [Term] id: CCO:F0002077 name: alkanesulfonate monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + SO3(2-) (sulfite) + H2O + FMN." [MetaCyc:RXN0-280] subset: gosubset_prok synonym: "alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity" EXACT [EC:1.14.14.5] synonym: "alkanesulphonate monooxygenase activity" EXACT [] synonym: "FMNH(2)-dependent aliphatic sulfonate monooxygenase activity" EXACT [EC:1.14.14.5] synonym: "FMNH(2)-dependent alkanesulfonate monooxygenase activity" EXACT [] synonym: "FMNH2-dependent aliphatic sulfonate monooxygenase activity" EXACT [EC:1.14.14.5] synonym: "SsuD" RELATED [EC:1.14.14.5] synonym: "sulfate starvation-induced protein 6 activity" RELATED [EC:1.14.14.5] xref: EC:1.14.14.5 xref: GO:0008726 xref: MetaCyc:RXN0-280 is_a: CCO:F0003295 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0002078 name: GDP-mannose mannosyl hydrolase activity namespace: molecular_function xref: GO:0008727 is_a: CCO:F0003018 ! mannosidase activity [Term] id: CCO:F0002079 name: GTP diphosphokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate." [EC:2.7.6.5] subset: gosubset_prok synonym: "(p)ppGpp synthetase I" RELATED [EC:2.7.6.5] synonym: "(p)ppGpp synthetase II" RELATED [EC:2.7.6.5] synonym: "ATP-GTP 3'-diphosphotransferase activity" EXACT [EC:2.7.6.5] synonym: "ATP:GTP 3'-diphosphotransferase activity" EXACT [EC:2.7.6.5] synonym: "GPSI" RELATED [EC:2.7.6.5] synonym: "GPSII" RELATED [EC:2.7.6.5] synonym: "GTP pyrophosphokinase activity" EXACT [] synonym: "guanosine 3',5'-polyphosphate synthase activity" EXACT [EC:2.7.6.5] synonym: "guanosine 5',3'-polyphosphate synthetase activity" EXACT [EC:2.7.6.5] synonym: "guanosine pentaphosphate synthetase activity" EXACT [EC:2.7.6.5] synonym: "ppGpp synthetase I activity" EXACT [EC:2.7.6.5] synonym: "stringent factor activity" RELATED [EC:2.7.6.5] xref: EC:2.7.6.5 xref: GO:0008728 xref: MetaCyc:GTPPYPHOSKIN-RXN is_a: CCO:F0003350 ! diphosphotransferase activity [Term] id: CCO:F0002080 name: L(+)-tartrate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (R,R)-tartrate = oxaloacetate + H2O." [EC:4.2.1.32] subset: gosubset_prok synonym: "(R,R)-tartrate hydro-lyase (oxaloacetate-forming)" EXACT [EC:4.2.1.32] synonym: "(R,R)-tartrate hydro-lyase activity" EXACT [EC:4.2.1.32] synonym: "L-(+)-tartaric acid dehydratase activity" EXACT [EC:4.2.1.32] synonym: "L-tartrate dehydratase activity" EXACT [EC:4.2.1.32] synonym: "tartaric acid dehydrase activity" EXACT [EC:4.2.1.32] synonym: "tartrate dehydratase activity" EXACT [EC:4.2.1.32] xref: EC:4.2.1.32 xref: GO:0008730 xref: MetaCyc:LTARTDEHYDRA-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002081 name: L-allo-threonine aldolase activity namespace: molecular_function def: "Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde." [MetaCyc:LTAA-RXN, PMID:9228760] subset: gosubset_prok synonym: "L-allo-threonine acetaldehyde-lyase activity" EXACT [] synonym: "LtaA" RELATED [] xref: EC:4.1.2.- xref: GO:0008732 xref: MetaCyc:LTAA-RXN is_a: CCO:F0001151 ! threonine aldolase activity [Term] id: CCO:F0002082 name: L-arabinose isomerase activity namespace: molecular_function def: "Catalysis of the reaction: L-arabinose = L-ribulose." [EC:5.3.1.4] subset: gosubset_prok synonym: "L-arabinose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.4] synonym: "L-arabinose ketol-isomerase activity" EXACT [EC:5.3.1.4] xref: EC:5.3.1.4 xref: GO:0008733 xref: MetaCyc:ARABISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002083 name: L-aspartate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2." [EC:1.4.3.16] subset: gosubset_prok synonym: "L-aspartate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.16] xref: EC:1.4.3.16 xref: GO:0008734 xref: MetaCyc:L-ASPARTATE-OXIDASE-RXN is_a: CCO:F0003017 ! aspartate oxidase activity [Term] id: CCO:F0002084 name: carnitine dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: L-carnitine = 4-(trimethylammonio)but-2-enoate + H2O." [EC:4.2.1.89] subset: gosubset_prok synonym: "L-carnitine dehydratase activity" EXACT [] synonym: "L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming]" RELATED [EC:4.2.1.89] synonym: "L-carnitine hydro-lyase activity" EXACT [EC:4.2.1.89] xref: EC:4.2.1.89 xref: GO:0008735 xref: MetaCyc:CARNDEHYDRA-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002085 name: L-fucose isomerase activity namespace: molecular_function def: "Catalysis of the reaction: L-fucose = L-fuculose." [EC:5.3.1.25] subset: gosubset_prok synonym: "L-fucose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.25] synonym: "L-fucose ketol-isomerase activity" EXACT [EC:5.3.1.25] xref: EC:5.3.1.25 xref: GO:0008736 xref: MetaCyc:FUCISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002086 name: L-fuculokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-fuculose = ADP + L-fuculose 1-phosphate." [EC:2.7.1.51] subset: gosubset_prok synonym: "ATP:L-fuculose 1-phosphotransferase activity" EXACT [EC:2.7.1.51] synonym: "L-fuculokinase (phosphorylating)" EXACT [EC:2.7.1.51] synonym: "L-fuculose kinase activity" EXACT [EC:2.7.1.51] xref: EC:2.7.1.51 xref: GO:0008737 xref: MetaCyc:FUCULOKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002087 name: L-fuculose-phosphate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde." [EC:4.1.2.17] subset: gosubset_prok synonym: "fuculose aldolase activity" EXACT [EC:4.1.2.17] synonym: "L-fuculose 1-phosphate aldolase activity" EXACT [EC:4.1.2.17] synonym: "L-fuculose-1-phosphate lactaldehyde-lyase activity" EXACT [EC:4.1.2.17] synonym: "L-fuculose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.17] xref: EC:4.1.2.17 xref: GO:0008738 xref: MetaCyc:FUCPALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0002088 name: L-rhamnose isomerase activity namespace: molecular_function def: "Catalysis of the reaction: L-rhamnose = L-rhamnulose." [EC:5.3.1.14] subset: gosubset_prok synonym: "L-rhamnose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.14] synonym: "L-rhamnose ketol-isomerase activity" EXACT [EC:5.3.1.14] synonym: "rhamnose isomerase activity" EXACT [EC:5.3.1.14] xref: EC:5.3.1.14 xref: GO:0008740 xref: MetaCyc:RHAMNISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002089 name: ribulokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate." [EC:2.7.1.16] subset: gosubset_prok synonym: "ATP:L(or D)-ribulose 5-phosphotransferase activity" EXACT [EC:2.7.1.16] synonym: "L-ribulokinase activity" EXACT [] synonym: "ribulokinase (phosphorylating)" EXACT [EC:2.7.1.16] xref: EC:2.7.1.16 xref: GO:0008741 xref: MetaCyc:RIBULOKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002090 name: L-ribulose-phosphate 4-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: L-ribulose 5-phosphate = D-xylose 5-phosphate." [EC:5.1.3.4] subset: gosubset_prok synonym: "AraD" RELATED [EC:5.1.3.4] synonym: "L-ribulose 5-phosphate 4-epimerase activity" EXACT [EC:5.1.3.4] synonym: "L-ribulose-5-phosphate 4-epimerase" BROAD [EC:5.1.3.4] synonym: "L-Ru5P" RELATED [EC:5.1.3.4] synonym: "L-ru5P activity" EXACT [EC:5.1.3.4] synonym: "phosphoribulose isomerase activity" EXACT [EC:5.1.3.4] synonym: "ribulose phosphate 4-epimerase activity" EXACT [EC:5.1.3.4] xref: EC:5.1.3.4 xref: GO:0008742 xref: MetaCyc:RIBULPEPIM-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0002091 name: L-threonine 3-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH + H+." [EC:1.1.1.103] subset: gosubset_prok synonym: "L-threonine dehydrogenase activity" EXACT [EC:1.1.1.103] synonym: "L-threonine:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.103] synonym: "threonine 3-dehydrogenase activity" BROAD [] synonym: "threonine dehydrogenase activity" EXACT [EC:1.1.1.103] xref: EC:1.1.1.103 xref: GO:0008743 xref: MetaCyc:THREODEHYD-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002092 name: L-xylulokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate." [EC:2.7.1.53] subset: gosubset_prok synonym: "ATP:L-xylulose 5-phosphotransferase activity" EXACT [EC:2.7.1.53] synonym: "L-xylulokinase (phosphorylating)" EXACT [EC:2.7.1.53] synonym: "L-xylulose kinase activity" EXACT [EC:2.7.1.53] xref: EC:2.7.1.53 xref: GO:0008744 xref: MetaCyc:LYXK-RXN is_a: CCO:F0001212 ! xylulokinase activity [Term] id: CCO:F0002093 name: N-acetylmuramoyl-L-alanine amidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides." [EC:3.5.1.28] subset: gosubset_prok synonym: "acetylmuramoyl-alanine amidase activity" EXACT [EC:3.5.1.28] synonym: "acetylmuramyl-alanine amidase activity" EXACT [EC:3.5.1.28] synonym: "acetylmuramyl-L-alanine amidase activity" EXACT [EC:3.5.1.28] synonym: "murein hydrolase activity" EXACT [EC:3.5.1.28] synonym: "N-acetylmuramic acid L-alanine amidase activity" EXACT [EC:3.5.1.28] synonym: "N-acetylmuramoyl-L-alanine amidase type I" RELATED [EC:3.5.1.28] synonym: "N-acetylmuramoyl-L-alanine amidase type II" RELATED [EC:3.5.1.28] synonym: "N-acetylmuramyl-L-alanine amidase activity" EXACT [EC:3.5.1.28] synonym: "N-acetylmuramylalanine amidase activity" EXACT [EC:3.5.1.28] synonym: "N-acylmuramyl-L-alanine amidase activity" EXACT [EC:3.5.1.28] synonym: "peptidoglycan amidohydrolase activity" EXACT [EC:3.5.1.28] xref: EC:3.5.1.28 xref: GO:0008745 xref: MetaCyc:3.5.1.28-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002094 name: NAD(P) transhydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+." [EC:1.6.1.1, EC:1.6.1.2] subset: gosubset_prok synonym: "energy-linked transhydrogenase" EXACT [EC:1.6.1.1, EC:1.6.1.2] synonym: "H+-thase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "NAD transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "NADH transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "NADH-NADP-transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "NADPH-NAD oxidoreductase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "NADPH-NAD transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "NADPH:NAD+ transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "nicotinamide adenine dinucleotide (phosphate) transhydrogenase" BROAD [EC:1.6.1.1, EC:1.6.1.2] synonym: "pyridine nucleotide transferase" BROAD [EC:1.6.1.1, EC:1.6.1.2] xref: EC:1.6.1.- xref: GO:0008746 is_a: CCO:F0003250 ! oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor [Term] id: CCO:F0002095 name: N-acetylneuraminate lyase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate." [EC:4.1.3.3] subset: gosubset_prok synonym: "acetylneuraminate lyase activity" EXACT [EC:4.1.3.3] synonym: "acetylneuraminate pyruvate-lyase activity" EXACT [EC:4.1.3.3] synonym: "N-acetylneuraminate aldolase activity" EXACT [EC:4.1.3.3] synonym: "N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)" EXACT [EC:4.1.3.3] synonym: "N-acetylneuraminate pyruvate-lyase activity" EXACT [EC:4.1.3.3] synonym: "N-acetylneuraminic acid aldolase activity" EXACT [EC:4.1.3.3] synonym: "N-acetylneuraminic acid lyase activity" EXACT [EC:4.1.3.3] synonym: "N-acetylneuraminic aldolase activity" EXACT [EC:4.1.3.3] synonym: "N-acetylneuraminic lyase activity" EXACT [EC:4.1.3.3] synonym: "NALase activity" EXACT [EC:4.1.3.3] synonym: "NANA lyase activity" EXACT [EC:4.1.3.3] synonym: "neuraminate aldolase activity" EXACT [EC:4.1.3.3] synonym: "neuraminic acid aldolase activity" EXACT [EC:4.1.3.3] synonym: "neuraminic aldolase activity" EXACT [EC:4.1.3.3] synonym: "NPL" RELATED [EC:4.1.3.3] synonym: "sialate lyase activity" EXACT [EC:4.1.3.3] synonym: "sialic acid aldolase activity" EXACT [EC:4.1.3.3] synonym: "sialic aldolase activity" EXACT [EC:4.1.3.3] xref: EC:4.1.3.3 xref: GO:0008747 xref: MetaCyc:ACNEULY-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0002096 name: N-ethylmaleimide reductase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008748 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002097 name: NAD(P)+ transhydrogenase (AB-specific) activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+." [EC:1.6.1.2, http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1991/113/i07/f-pdf/f_ja00007a002.pdf?sessid] subset: gosubset_prok synonym: "NAD(P) transhydrogenase (AB-specific) activity" EXACT [EC:1.6.1.2] synonym: "NADPH:NAD+ oxidoreductase (AB-specific)" EXACT [EC:1.6.1.2] synonym: "pyridine nucleotide transhydrogenase activity" BROAD [EC:1.6.1.2] synonym: "transhydrogenase activity" BROAD [EC:1.6.1.2] xref: EC:1.6.1.2 xref: GO:0008750 xref: MetaCyc:1.6.1.2-RXN is_a: CCO:F0002094 ! NAD(P) transhydrogenase activity [Term] id: CCO:F0002098 name: FMN reductase activity namespace: molecular_function def: "Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+." [EC:1.5.1.29] subset: gosubset_prok synonym: "flavin mononucleotide reductase activity" EXACT [EC:1.5.1.29] synonym: "flavine mononucleotide reductase activity" EXACT [EC:1.5.1.29] synonym: "FMNH2:NAD(P)+ oxidoreductase activity" EXACT [EC:1.5.1.29] synonym: "NAD(P)H dehydrogenase (FMN) activity" EXACT [] synonym: "NAD(P)H(2) dehydrogenase (FMN) activity" EXACT [EC:1.5.1.29] synonym: "NAD(P)H(2):FMN oxidoreductase activity" EXACT [EC:1.5.1.29] synonym: "NAD(P)H-dependent FMN reductase activity" EXACT [EC:1.5.1.29] synonym: "NAD(P)H-FMN reductase activity" EXACT [EC:1.5.1.29] synonym: "NAD(P)H2 dehydrogenase (FMN)" EXACT [EC:1.5.1.29] synonym: "NAD(P)H2:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] synonym: "NAD(P)H:flavin oxidoreductase activity" EXACT [EC:1.5.1.29] synonym: "NAD(P)H:FMN oxidoreductase activity" EXACT [EC:1.5.1.29] synonym: "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase activity" EXACT [EC:1.5.1.29] synonym: "riboflavin mononucleotide reductase activity" BROAD [EC:1.5.1.29] synonym: "riboflavine mononucleotide reductase activity" BROAD [EC:1.5.1.29] synonym: "SsuE" RELATED [EC:1.5.1.29] xref: EC:1.5.1.29 xref: GO:0008752 xref: MetaCyc:FMNREDUCT-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002099 name: NADPH dehydrogenase (quinone) activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor." [EC:1.6.99.6] subset: gosubset_prok synonym: "NADPH oxidase" BROAD [EC:1.6.99.6] synonym: "NADPH:(quinone-acceptor) oxidoreductase" EXACT [EC:1.6.99.6] synonym: "reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase" EXACT [EC:1.6.99.6] xref: EC:1.6.99.6 xref: GO:0008753 xref: MetaCyc:NADPH-DEHYDROGENASE-(QUINONE)-RXN is_a: CCO:F0000452 ! NADPH dehydrogenase activity [Term] id: CCO:F0002100 name: O antigen ligase activity namespace: molecular_function xref: GO:0008754 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0002101 name: O antigen polymerase activity namespace: molecular_function def: "Catalysis of the polymerization of o-antigen chains. O-antigens are tetra and penta saccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "O-antigen polymerase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0008755 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0002102 name: o-succinylbenzoate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + O-succinylbenzoate + CoA = AMP + diphosphate + O-succinylbenzoyl-CoA." [EC:6.2.1.26] subset: gosubset_prok synonym: "2-succinylbenzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.26] synonym: "o-succinylbenzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.26] synonym: "o-succinylbenzoyl-CoA synthetase activity" EXACT [EC:6.2.1.26] synonym: "o-succinylbenzoyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.26] synonym: "OSB-CoA synthetase activity" EXACT [EC:6.2.1.26] synonym: "osb-CoA synthetase activity" EXACT [EC:6.2.1.26] xref: EC:6.2.1.26 xref: GO:0008756 xref: MetaCyc:O-SUCCINYLBENZOATE-COA-LIG-RXN is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0002103 name: S-adenosylmethionine-dependent methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate." [GOC:mah] subset: gosubset_prok synonym: "S-adenosyl methionine-dependent methyltransferase activity" EXACT [] synonym: "SAM-dependent methyltransferase activity" EXACT [] xref: GO:0008757 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0002104 name: UDP-2,3-diacylglucosamine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP." [MetaCyc:LIPIDXSYNTHESIS-RXN, PMID:12000770] subset: gosubset_prok xref: EC:3.6.1.- xref: GO:0008758 xref: MetaCyc:LIPIDXSYNTHESIS-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0002105 name: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity namespace: molecular_function def: "Catalysis of the removal of an acetyl moiety from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine." [PMID:10026271] subset: gosubset_prok xref: EC:3.5.1.- xref: GO:0008759 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0002106 name: UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine." [EC:2.5.1.7] subset: gosubset_prok synonym: "enoylpyruvate transferase activity" EXACT [EC:2.5.1.7] synonym: "MurA transferase activity" NARROW [EC:2.5.1.7] synonym: "phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase activity" EXACT [EC:2.5.1.7] synonym: "phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase activity" EXACT [EC:2.5.1.7] synonym: "phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase activity" EXACT [EC:2.5.1.7] synonym: "phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase activity" EXACT [EC:2.5.1.7] synonym: "phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase activity" EXACT [EC:2.5.1.7] synonym: "phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase activity" EXACT [EC:2.5.1.7] synonym: "pyruvate-UDP-acetylglucosamine transferase activity" EXACT [EC:2.5.1.7] synonym: "pyruvate-uridine diphospho-N-acetyl-glucosamine transferase activity" EXACT [EC:2.5.1.7] synonym: "pyruvate-uridine diphospho-N-acetylglucosamine transferase activity" EXACT [EC:2.5.1.7] synonym: "pyruvic-uridine diphospho-N-acetylglucosaminyltransferase activity" EXACT [EC:2.5.1.7] synonym: "UDP-N-acetylglucosamine 1-carboxyvinyl-transferase activity" EXACT [EC:2.5.1.7] synonym: "UDP-N-acetylglucosamine enoylpyruvyltransferase activity" EXACT [EC:2.5.1.7] xref: EC:2.5.1.7 xref: GO:0008760 xref: MetaCyc:UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0002107 name: UDP-N-acetylglucosamine 2-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine." [EC:5.1.3.14] subset: gosubset_prok synonym: "UDP-GlcNAc-2-epimerase activity" EXACT [EC:5.1.3.14] synonym: "UDP-N-acetyl-D-glucosamine 2-epimerase activity" EXACT [EC:5.1.3.14] synonym: "UDP-N-acetylglucosamine 2'-epimerase activity" EXACT [EC:5.1.3.14] synonym: "uridine diphosphate-N-acetylglucosamine-2'-epimerase activity" EXACT [EC:5.1.3.14] synonym: "uridine diphospho-N-acetylglucosamine 2'-epimerase activity" EXACT [EC:5.1.3.14] synonym: "uridine diphosphoacetylglucosamine 2'-epimerase activity" EXACT [EC:5.1.3.14] xref: EC:5.1.3.14 xref: GO:0008761 xref: MetaCyc:UDPGLCNACEPIM-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0002108 name: UDP-N-acetylmuramate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+." [EC:1.1.1.158] subset: gosubset_prok synonym: "MurB reductase" RELATED [EC:1.1.1.158] synonym: "UDP-GlcNAc-enoylpyruvate reductase activity" EXACT [EC:1.1.1.158] synonym: "UDP-N-acetylenolpyruvoylglucosamine reductase activity" EXACT [EC:1.1.1.158] synonym: "UDP-N-acetylglucosamine-enoylpyruvate reductase activity" EXACT [EC:1.1.1.158] synonym: "UDP-N-acetylmuramate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.158] synonym: "uridine diphospho-N-acetylglucosamine-enolpyruvate reductase activity" EXACT [EC:1.1.1.158] synonym: "uridine diphosphoacetylpyruvoylglucosamine reductase activity" EXACT [EC:1.1.1.158] synonym: "uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase activity" EXACT [EC:1.1.1.158] xref: EC:1.1.1.158 xref: GO:0008762 xref: MetaCyc:UDPNACETYLMURAMATEDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002109 name: UDP-N-acetylmuramate-L-alanine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine." [EC:6.3.2.8] subset: gosubset_prok synonym: "alanine-adding enzyme activity" RELATED [EC:6.3.2.8] synonym: "L-Ala ligase activity" RELATED [EC:6.3.2.8] synonym: "L-alanine-adding enzyme activity" RELATED [EC:6.3.2.8] synonym: "MurC synthetase activity" NARROW [EC:6.3.2.8] synonym: "UDP-acetylmuramyl-L-alanine synthetase activity" EXACT [EC:6.3.2.8] synonym: "UDP-MurNAc:L-alanine ligase activity" EXACT [EC:6.3.2.8] synonym: "UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.8] synonym: "UDP-N-acetylmuramoyl-L-alanine synthetase activity" EXACT [EC:6.3.2.8] synonym: "UDP-N-acetylmuramoylalanine synthetase activity" EXACT [EC:6.3.2.8] synonym: "UDP-N-acetylmuramyl:L-alanine ligase activity" EXACT [EC:6.3.2.8] synonym: "UDPMurNAc-L-alanine synthetase activity" EXACT [EC:6.3.2.8] synonym: "uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity" EXACT [EC:6.3.2.8] synonym: "uridine diphosphate N-acetylmuramate:L-alanine ligase activity" EXACT [EC:6.3.2.8] synonym: "uridine diphospho-N-acetylmuramoylalanine synthetase activity" EXACT [EC:6.3.2.8] synonym: "uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity" EXACT [EC:6.3.2.8] xref: EC:6.3.2.8 xref: GO:0008763 xref: MetaCyc:UDP-NACMUR-ALA-LIG-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0002110 name: UDP-N-acetylmuramoylalanine-D-glutamate ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate." [EC:6.3.2.9] subset: gosubset_prok synonym: "D-glutamate ligase activity" RELATED [EC:6.3.2.9] synonym: "D-glutamate-adding enzyme activity" RELATED [EC:6.3.2.9] synonym: "MurD synthetase activity" EXACT [EC:6.3.2.9] synonym: "UDP-Mur-NAC-L-Ala:D-Glu ligase activity" EXACT [EC:6.3.2.9] synonym: "UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)" EXACT [EC:6.3.2.9] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity" EXACT [EC:6.3.2.9] synonym: "uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity" EXACT [EC:6.3.2.9] xref: EC:6.3.2.9 xref: GO:0008764 xref: MetaCyc:UDP-NACMURALA-GLU-LIG-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0002111 name: UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate." [EC:6.3.2.13] subset: gosubset_prok synonym: "MurE synthetase activity" RELATED [EC:6.3.2.13] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.13] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity" EXACT [EC:6.3.2.13] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity" EXACT [EC:6.3.2.13] synonym: "UDP-N-acetylmuramyl-tripeptide synthetase activity" EXACT [EC:6.3.2.13] xref: EC:6.3.2.13 xref: GO:0008765 xref: MetaCyc:UDP-NACMURALGLDAPLIG-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0002112 name: UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine." [EC:6.3.2.15] comment: Note that EC:6.3.2.15 was deleted from EC as the reaction is performed by UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (EC:6.3.2.10). subset: gosubset_prok xref: EC:6.3.2.- xref: GO:0008766 xref: MetaCyc:UDP-NACMURALGLDAPAALIG-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0002113 name: UDP-galactopyranose mutase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose." [EC:5.4.99.9] subset: gosubset_prok synonym: "UDP-D-galactopyranose furanomutase activity" EXACT [EC:5.4.99.9] synonym: "UDPgalactopyranose mutase activity" EXACT [EC:5.4.99.9] xref: EC:5.4.99.9 xref: GO:0008767 xref: MetaCyc:GALPMUT-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0002114 name: UDP-sugar diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate." [EC:3.6.1.45] subset: gosubset_prok synonym: "nucleosidediphosphate-sugar diphosphatase activity" EXACT [EC:3.6.1.45] synonym: "nucleosidediphosphate-sugar pyrophosphatase activity" EXACT [EC:3.6.1.45] synonym: "UDP-sugar hydrolase activity" EXACT [EC:3.6.1.45] synonym: "UDP-sugar pyrophosphatase activity" EXACT [EC:3.6.1.45] synonym: "UDP-sugar sugarphosphohydrolase activity" EXACT [EC:3.6.1.45] xref: EC:3.6.1.45 xref: GO:0008768 xref: MetaCyc:UDPSUGARHYDRO-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0002115 name: X-His dipeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of Xaa-His dipeptides." [EC:3.4.13.3] subset: gosubset_prok synonym: "aminoacyl-histidine dipeptidase activity" EXACT [EC:3.4.13.3] synonym: "aminoacylhistidine dipeptidase activity" EXACT [EC:3.4.13.3] synonym: "carnosinase activity" RELATED [EC:3.4.13.3] synonym: "dipeptidase M" RELATED [EC:3.4.13.3] synonym: "homocarnosinase activity" RELATED [EC:3.4.13.3] synonym: "Xaa-His dipeptidase activity" EXACT [] xref: EC:3.4.13.3 xref: GO:0008769 xref: MetaCyc:3.4.13.3-RXN is_a: CCO:F0001785 ! metalloexopeptidase activity is_a: CCO:F0003375 ! dipeptidase activity [Term] id: CCO:F0002120 name: acetaldehyde dehydrogenase (acetylating) activity namespace: molecular_function def: "Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+." [EC:1.2.1.10] subset: gosubset_prok synonym: "acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.1.10] synonym: "acylating acetaldehyde dehydrogenase activity" EXACT [EC:1.2.1.10] synonym: "ADA" RELATED [EC:1.2.1.10] synonym: "aldehyde dehydrogenase (acylating) activity" EXACT [EC:1.2.1.10] synonym: "DmpF" RELATED [EC:1.2.1.10] xref: EC:1.2.1.10 xref: GO:0008774 xref: MetaCyc:ACETALD-DEHYDROG-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002121 name: acetate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA." [EC:2.8.3.8] subset: gosubset_prok synonym: "acetate coenzyme A-transferase activity" EXACT [EC:2.8.3.8] synonym: "acetyl-CoA:acetoacetate CoA transferase activity" EXACT [EC:2.8.3.8] synonym: "acyl-CoA:acetate CoA-transferase activity" EXACT [EC:2.8.3.8] synonym: "butyryl CoA:acetate CoA transferase activity" EXACT [EC:2.8.3.8] synonym: "butyryl coenzyme A transferase activity" EXACT [EC:2.8.3.8] synonym: "succinyl-CoA:acetate CoA transferase activity" EXACT [EC:2.8.3.8] xref: EC:2.8.3.8 xref: GO:0008775 xref: MetaCyc:ACECOATRANS-RXN xref: UM-BBD_enzymeID:e0012 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0002122 name: acetate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate." [EC:2.7.2.1] subset: gosubset_prok synonym: "acetate kinase (phosphorylating) activity" EXACT [EC:2.7.2.1] synonym: "acetic kinase activity" EXACT [EC:2.7.2.1] synonym: "acetokinase activity" EXACT [EC:2.7.2.1] synonym: "AckA" RELATED [EC:2.7.2.1] synonym: "AK activity" EXACT [EC:2.7.2.1] synonym: "ATP:acetate phosphotransferase activity" EXACT [EC:2.7.2.1] xref: EC:2.7.2.1 xref: GO:0008776 xref: MetaCyc:ACETATEKIN-RXN xref: UM-BBD_enzymeID:e0031 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0002123 name: acetylornithine deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine." [EC:3.5.1.16] subset: gosubset_prok synonym: "2-N-acetyl-L-ornithine amidohydrolase activity" EXACT [EC:3.5.1.16] synonym: "acetylornithinase activity" BROAD [EC:3.5.1.16] synonym: "N-acetylornithinase activity" BROAD [EC:3.5.1.16] synonym: "N2-acetyl-L-ornithine amidohydrolase activity" EXACT [EC:3.5.1.16] xref: EC:3.5.1.16 xref: GO:0008777 xref: MetaCyc:ACETYLORNDEACET-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0002124 name: acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine." [EC:2.3.1.40] synonym: "acyl-[acyl-carrier protein]-phospholipid O-acyltransferase activity" EXACT [] synonym: "acyl-ACP-phospholipid O-acyltransferase activity" EXACT [] synonym: "acyl-acyl-carrier-protein-phospholipid O-acyltransferase activity" EXACT [EC:2.3.1.40] synonym: "acyl-acyl-carrier-protein:O-(2-acyl-sn-glycero-3-phospho)-ethanolamine O-acyltransferase activity" EXACT [EC:2.3.1.40] xref: EC:2.3.1.40 xref: GO:0008779 xref: MetaCyc:ACYLGPEACYLTRANS-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0002125 name: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine." [EC:2.3.1.129] subset: gosubset_prok synonym: "(R)-3-hydroxytetradecanoyl-acyl-carrier-protein:UDP-N-acetylglucosamine 3-O-(3-hydroxytetradecanoyl)transferase activity" EXACT [EC:2.3.1.129] synonym: "acyl-[acyl-carrier protein]-UDP-N-acetylglucosamine O-acyltransferase activity" EXACT [] synonym: "acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase activity" EXACT [] synonym: "acyl-acyl-carrier-protein-UDP-N-acetylglucosamine O-acyltransferase" BROAD [EC:2.3.1.129] synonym: "UDP-N-acetylglucosamine acyltransferase activity" EXACT [EC:2.3.1.129] synonym: "uridine diphosphoacetylglucosamine acyltransferase activity" EXACT [EC:2.3.1.129] xref: EC:2.3.1.129 xref: GO:0008780 xref: MetaCyc:UDPNACETYLGLUCOSAMACYLTRANS-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0002126 name: N-acylneuraminate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate." [EC:2.7.7.43] subset: gosubset_prok synonym: "acetylneuraminate cytidylyltransferase activity" EXACT [EC:2.7.7.43] synonym: "acylneuraminate cytidyltransferase activity" EXACT [EC:2.7.7.43] synonym: "CMP-N-acetylneuraminate synthase activity" EXACT [EC:2.7.7.43] synonym: "CMP-N-acetylneuraminate synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-N-acetylneuraminic acid synthase activity" EXACT [EC:2.7.7.43] synonym: "CMP-N-acetylneuraminic acid synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-NANA synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-Neu5Ac synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-NeuAc synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-NeuNAc synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-sialate diphosphorylase activity" EXACT [EC:2.7.7.43] synonym: "CMP-sialate pyrophosphorylase activity" EXACT [EC:2.7.7.43] synonym: "CMP-sialate synthase activity" EXACT [EC:2.7.7.43] synonym: "CMP-sialate synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-sialic acid synthetase activity" EXACT [EC:2.7.7.43] synonym: "CMP-sialic synthetase activity" EXACT [EC:2.7.7.43] synonym: "CTP:N-acylneuraminate cytidylyltransferase activity" EXACT [] synonym: "cytidine 5'-monophospho-N-acetylneuraminic acid synthetase activity" EXACT [EC:2.7.7.43] synonym: "cytidine 5'-monophosphosialic acid synthetase activity" EXACT [EC:2.7.7.43] synonym: "cytidine 5-monophosphate N-acetylneuraminic acid synthetase activity" EXACT [EC:2.7.7.43] synonym: "cytidine monophosphoacetylneuraminic synthetase activity" EXACT [EC:2.7.7.43] synonym: "cytidine monophosphosialate pyrophosphorylase activity" EXACT [EC:2.7.7.43] synonym: "cytidine monophosphosialate synthetase activity" EXACT [EC:2.7.7.43] synonym: "cytidine monophosphosialic acid synthetase activity" EXACT [EC:2.7.7.43] xref: EC:2.7.7.43 xref: GO:0008781 xref: MetaCyc:ACYLNEURAMINATE-CYTIDYLYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002127 name: adenosylhomocysteine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine." [EC:3.2.2.9] subset: gosubset_prok synonym: "5'-methyladenosine nucleosidase activity" EXACT [EC:3.2.2.9] synonym: "AdoHcy/MTA nucleosidase activity" EXACT [EC:3.2.2.9] synonym: "S-adenosyl-L-homocysteine homocysteinylribohydrolase activity" EXACT [EC:3.2.2.9] synonym: "S-adenosylhomocysteine hydrolase activity" BROAD [EC:3.2.2.9] synonym: "S-adenosylhomocysteine nucleosidase activity" EXACT [EC:3.2.2.9] synonym: "S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity" EXACT [EC:3.2.2.9] xref: EC:3.2.2.9 xref: GO:0008782 xref: MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0002128 name: agmatinase activity namespace: molecular_function def: "Catalysis of the reaction: agmatine + H2O = putrescine + urea." [EC:3.5.3.11] subset: gosubset_prok synonym: "agmatine amidinohydrolase" BROAD [EC:3.5.3.11] synonym: "agmatine ureohydrolase activity" EXACT [EC:3.5.3.11] synonym: "SpeB" RELATED [EC:3.5.3.11] xref: EC:3.5.3.11 xref: GO:0008783 xref: MetaCyc:AGMATIN-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0002129 name: alanine racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-alanine = D-alanine." [EC:5.1.1.1] subset: gosubset_prok synonym: "L-alanine racemase activity" EXACT [EC:5.1.1.1] xref: EC:5.1.1.1 xref: GO:0008784 xref: MetaCyc:ALARACECAT-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0002130 name: alkyl hydroperoxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol." [UM-BBD_enzymeID:e0429] subset: gosubset_prok xref: EC:1.6.4.- xref: GO:0008785 xref: UM-BBD_enzymeID:e0429 is_a: CCO:F0003252 ! oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor [Term] id: CCO:F0002131 name: allose 6-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate." [MetaCyc:RXN0-303] xref: EC:5.3.1.- xref: GO:0008786 xref: MetaCyc:RXN0-303 is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002132 name: allose kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate." [EC:2.7.1.55] subset: gosubset_prok synonym: "allokinase (phosphorylating)" EXACT [EC:2.7.1.55] synonym: "allokinase activity" EXACT [EC:2.7.1.55] synonym: "ATP:D-allose 6-phosphotransferase activity" EXACT [EC:2.7.1.55] synonym: "D-allokinase activity" EXACT [EC:2.7.1.55] synonym: "D-allose-6-kinase activity" EXACT [EC:2.7.1.55] xref: EC:2.7.1.55 xref: GO:0008787 xref: MetaCyc:ALLOSE-KINASE-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002133 name: alpha,alpha-phosphotrehalase activity namespace: molecular_function def: "Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate." [EC:3.2.1.93] subset: gosubset_prok synonym: "alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase activity" EXACT [EC:3.2.1.93] synonym: "phosphotrehalase activity" EXACT [EC:3.2.1.93] synonym: "trehalose-6-phosphate hydrolase activity" EXACT [EC:3.2.1.93] xref: EC:3.2.1.93 xref: GO:0008788 xref: MetaCyc:TRE6PHYDRO-RXN is_a: CCO:F0003022 ! trehalase activity [Term] id: CCO:F0002134 name: altronate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O." [EC:4.2.1.7] subset: gosubset_prok synonym: "D-altronate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)" EXACT [EC:4.2.1.7] synonym: "D-altronate hydro-lyase activity" EXACT [EC:4.2.1.7] xref: EC:4.2.1.7 xref: GO:0008789 xref: MetaCyc:ALTRODEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002135 name: arabinose isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinose = D-ribulose." [EC:5.3.1.3] synonym: "D-arabinose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.3] synonym: "D-arabinose isomerase activity" NARROW [EC:5.3.1.3] synonym: "D-arabinose ketol-isomerase activity" EXACT [EC:5.3.1.3] synonym: "D-arabinose(L-fucose) isomerase activity" EXACT [EC:5.3.1.3] xref: EC:5.3.1.3 xref: GO:0008790 xref: MetaCyc:DARABISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002136 name: arginine N-succinyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine." [EC:2.3.1.109] subset: gosubset_prok synonym: "AOST activity" EXACT [EC:2.3.1.109] synonym: "arginine and ornithine N(2)-succinyltransferase activity" EXACT [EC:2.3.1.109] synonym: "arginine and ornithine N2-succinyltransferase activity" EXACT [EC:2.3.1.109] synonym: "arginine succinyltransferase activity" EXACT [EC:2.3.1.109] synonym: "AST activity" EXACT [EC:2.3.1.109] synonym: "AstA" RELATED [EC:2.3.1.109] synonym: "succinyl-CoA:L-arginine 2-N-succinyltransferase activity" EXACT [EC:2.3.1.109] synonym: "succinyl-CoA:L-arginine N2-succinyltransferase activity" EXACT [EC:2.3.1.109] xref: EC:2.3.1.109 xref: GO:0008791 xref: MetaCyc:ARGININE-N-SUCCINYLTRANSFERASE-RXN is_a: CCO:F0003324 ! N-succinyltransferase activity [Term] id: CCO:F0002137 name: arginine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine = agmatine + CO2." [EC:4.1.1.19] subset: gosubset_prok synonym: "L-arginine carboxy-lyase (agmatine-forming)" EXACT [EC:4.1.1.19] synonym: "L-arginine carboxy-lyase activity" EXACT [EC:4.1.1.19] synonym: "SpeA" RELATED [EC:4.1.1.19] xref: EC:4.1.1.19 xref: GO:0008792 xref: MetaCyc:ARGDECARBOX-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002138 name: aromatic-amino-acid transaminase activity namespace: molecular_function def: "Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate." [EC:2.6.1.57] subset: gosubset_prok synonym: "ArAT" RELATED [EC:2.6.1.57] synonym: "aromatic amino acid aminotransferase activity" EXACT [EC:2.6.1.57] synonym: "aromatic amino acid transferase activity" EXACT [] synonym: "aromatic aminotransferase activity" EXACT [] synonym: "aromatic-amino-acid:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.57] xref: EC:2.6.1.57 xref: GO:0008793 xref: UM-BBD_enzymeID:e0142 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0002139 name: arsenate reductase (glutaredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione." [EC:1.20.4.1, GOC:kd, PMID:10593884] subset: gosubset_prok synonym: "glutharedoxin:arsenate oxidoreductase activity" EXACT [EC:1.20.4.1] xref: EC:1.20.4.1 xref: GO:0008794 xref: MetaCyc:RXN-982 xref: UM-BBD_enzymeID:e0261 is_a: CCO:F0004498 ! arsenate reductase activity is_a: CCO:F0004501 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulfide as acceptor [Term] id: CCO:F0002140 name: NAD+ synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+." [EC:6.3.1.5] subset: gosubset_prok synonym: "deamido-NAD+:ammonia ligase (AMP-forming)" EXACT [EC:6.3.1.5] synonym: "diphosphopyridine nucleotide synthetase activity" EXACT [EC:6.3.1.5] synonym: "NAD synthase (AMP-forming)" EXACT [] synonym: "NAD synthase activity" EXACT [] synonym: "NAD synthetase activity" EXACT [EC:6.3.1.5] synonym: "NAD(+) synthetase activity" EXACT [EC:6.3.1.5] synonym: "NAD+ synthetase activity" EXACT [EC:6.3.1.5] synonym: "nicotinamide adenine dinucleotide synthetase activity" EXACT [EC:6.3.1.5] xref: EC:6.3.1.5 xref: GO:0008749 xref: GO:0008795 xref: GO:0016965 xref: MetaCyc:NAD-SYNTH-NH3-RXN is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0002141 name: bis(5'-nucleosyl)-tetraphosphatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides." [GOC:ai] subset: gosubset_prok xref: EC:3.6.1.- xref: GO:0008796 is_a: CCO:F0000937 ! nucleotide diphosphatase activity [Term] id: CCO:F0002142 name: aspartate ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate = fumarate + NH3." [EC:4.3.1.1] subset: gosubset_prok synonym: "aspartase activity" EXACT [EC:4.3.1.1] synonym: "fumaric aminase activity" EXACT [EC:4.3.1.1] synonym: "L-aspartase activity" EXACT [EC:4.3.1.1] synonym: "L-aspartate ammonia-lyase (fumarate-forming)" EXACT [EC:4.3.1.1] synonym: "L-aspartate ammonia-lyase activity" EXACT [EC:4.3.1.1] xref: EC:4.3.1.1 xref: GO:0008797 xref: MetaCyc:ASPARTASE-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0002143 name: beta-aspartyl-peptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide." [EC:3.4.19.5] subset: gosubset_prok synonym: "beta-aspartyl dipeptidase activity" EXACT [EC:3.4.19.5] synonym: "beta-aspartyl peptidase activity" EXACT [EC:3.4.19.5] xref: EC:3.4.19.5 xref: GO:0008798 xref: MetaCyc:3.4.19.5-RXN is_a: CCO:F0001792 ! omega peptidase activity [Term] id: CCO:F0002144 name: beta-lactamase activity namespace: molecular_function def: "Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid." [EC:3.5.2.6] subset: gosubset_prok synonym: "ampicillinase activity" EXACT [EC:3.5.2.6] synonym: "beta-lactam hydrolase activity" EXACT [EC:3.5.2.6] synonym: "beta-lactamase A, B, C" RELATED [EC:3.5.2.6] synonym: "beta-lactamase AME I" RELATED [EC:3.5.2.6] synonym: "beta-lactamase I-III" RELATED [EC:3.5.2.6] synonym: "cephalosporin-beta-lactamase activity" EXACT [EC:3.5.2.6] synonym: "exopenicillinase activity" EXACT [EC:3.5.2.6] synonym: "neutrapen" RELATED [EC:3.5.2.6] synonym: "penicillin amido-beta-lactamhydrolase activity" EXACT [EC:3.5.2.6] synonym: "penicillin beta-lactamase activity" EXACT [EC:3.5.2.6] synonym: "penicillinase I, II" RELATED [EC:3.5.2.6] xref: EC:3.5.2.6 xref: GO:0008800 xref: MetaCyc:BETA-LACTAMASE-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0002145 name: beta-phosphoglucomutase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate." [EC:5.4.2.6] subset: gosubset_prok synonym: "beta-D-glucose 1,6-phosphomutase activity" EXACT [EC:5.4.2.6] xref: EC:5.4.2.6 xref: GO:0008801 xref: MetaCyc:BETA-PHOSPHOGLUCOMUTASE-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0002146 name: betaine-aldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+." [EC:1.2.1.8] subset: gosubset_prok synonym: "BADH activity" EXACT [EC:1.2.1.8] synonym: "betaine aldehyde dehydrogenase activity" EXACT [EC:1.2.1.8] synonym: "betaine aldehyde oxidase activity" EXACT [EC:1.2.1.8] synonym: "betaine-aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.8] synonym: "BetB" RELATED [EC:1.2.1.8] xref: EC:1.2.1.8 xref: GO:0008802 xref: MetaCyc:BADH-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002147 name: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity namespace: molecular_function def: "Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = 2 NDP." [EC:3.6.1.41, PMID:6317672] subset: gosubset_prok synonym: "1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity" EXACT [EC:3.6.1.41] synonym: "adenosine tetraphosphate phosphodiesterase activity" EXACT [EC:3.6.1.41] synonym: "Ap(4)A hydrolase activity" BROAD [EC:3.6.1.41] synonym: "Ap4A hydrolase activity" BROAD [EC:3.6.1.41] synonym: "bis(5'-adenosyl) tetraphosphatase activity" EXACT [EC:3.6.1.41] synonym: "diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase activity" EXACT [EC:3.6.1.41] synonym: "diadenosine 5',5'''-P1,P4-tetraphosphatase activity" EXACT [EC:3.6.1.41] synonym: "diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase activity" EXACT [EC:3.6.1.41] synonym: "diadenosine polyphosphate hydrolase activity" EXACT [EC:3.6.1.41] synonym: "diadenosine tetraphosphatase (symmetrical)" NARROW [] synonym: "diadenosine tetraphosphate hydrolase activity" EXACT [EC:3.6.1.41] synonym: "diadenosinetetraphosphatase (symmetrical) activity" EXACT [EC:3.6.1.41] synonym: "dinucleosidetetraphosphatase (symmetrical) activity" EXACT [EC:3.6.1.41] synonym: "dinucleosidetetraphosphate (symmetrical)" RELATED [EC:3.6.1.41] synonym: "P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity" EXACT [EC:3.6.1.41] synonym: "symmetrical diadenosine tetraphosphate hydrolase activity" EXACT [EC:3.6.1.41] xref: EC:3.6.1.41 xref: GO:0008803 xref: MetaCyc:3.6.1.41-RXN is_a: CCO:F0002141 ! bis(5'-nucleosyl)-tetraphosphatase activity [Term] id: CCO:F0002148 name: carbamate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate." [EC:2.7.2.2] subset: gosubset_prok synonym: "ATP:carbamate phosphotransferase activity" EXACT [EC:2.7.2.2] synonym: "carbamoyl phosphokinase activity" EXACT [EC:2.7.2.2] synonym: "carbamyl phosphokinase activity" EXACT [EC:2.7.2.2] synonym: "CKase activity" EXACT [EC:2.7.2.2] xref: EC:2.7.2.2 xref: GO:0008804 xref: MetaCyc:CARBAMATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0002149 name: carbon-monoxide oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561." [EC:1.2.2.4] synonym: "carbon monoxide oxidase activity" EXACT [EC:1.2.2.4] synonym: "carbon monoxide oxygenase (cytochrome b-561) activity" NARROW [EC:1.2.2.4] synonym: "carbon monoxide oxygenase activity" EXACT [] synonym: "carbon monoxide,water:cytochrome b-561 oxidoreductase activity" EXACT [EC:1.2.2.4] synonym: "carbon monoxide:methylene blue oxidoreductase activity" NARROW [EC:1.2.2.4] synonym: "carbon-monoxide dehydrogenase (cytochrome b-561)" EXACT [EC:1.2.2.4] synonym: "cytochrome b561" NARROW [] xref: EC:1.2.2.4 xref: GO:0008805 xref: GO:0018999 xref: GO:0047767 xref: MetaCyc:1.2.2.4-RXN xref: UM-BBD_enzymeID:e0180 is_a: CCO:F0003224 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor [Term] id: CCO:F0002150 name: carboxymethylenebutenolidase activity namespace: molecular_function def: "Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate." [EC:3.1.1.45] subset: gosubset_prok synonym: "4-carboxymethylenebut-2-en-4-olide lactonohydrolase activity" EXACT [EC:3.1.1.45] synonym: "carboxymethylene butenolide hydrolase activity" EXACT [EC:3.1.1.45] synonym: "dienelactone hydrolase activity" EXACT [EC:3.1.1.45] synonym: "maleylacetate enol-lactonase activity" EXACT [EC:3.1.1.45] xref: EC:3.1.1.45 xref: GO:0008806 xref: GO:0018735 xref: MetaCyc:CARBOXYMETHYLENEBUTENOLIDASE-RXN xref: UM-BBD_enzymeID:e0066 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0002151 name: carboxyvinyl-carboxyphosphonate phosphorylmutase activity namespace: molecular_function def: "Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2." [EC:2.7.8.23] subset: gosubset_prok synonym: "1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)" EXACT [EC:2.7.8.23] synonym: "carboxyphosphonoenolpyruvate phosphonomutase activity" EXACT [EC:2.7.8.23] synonym: "CPEP phosphonomutase activity" EXACT [EC:2.7.8.23] xref: EC:2.7.8.23 xref: GO:0008807 xref: MetaCyc:2.7.8.23-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0002152 name: cardiolipin synthase activity namespace: molecular_function def: "Phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol." [GOC:jl] subset: gosubset_prok synonym: "cardiolipin synthetase activity" BROAD [] synonym: "diphosphatidylglycerol synthase activity" EXACT [] xref: EC:2.7.8.- xref: GO:0008808 xref: MetaCyc:CARDIOLIPSYN-RXN is_a: CCO:F0004483 ! phosphatidyltransferase activity [Term] id: CCO:F0002153 name: carnitine racemase activity namespace: molecular_function def: "Catalysis of the reaction: D-carnitine = L-carnitine." [MetaCyc:CARNRACE-RXN] xref: EC:5.1.-.- xref: GO:0008809 xref: MetaCyc:CARNRACE-RXN is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0002154 name: cellulase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans." [EC:3.2.1.4] subset: gosubset_prok synonym: "1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.4] synonym: "9.5 cellulase activity" EXACT [EC:3.2.1.4] synonym: "alkali cellulase activity" EXACT [EC:3.2.1.4] synonym: "avicelase activity" BROAD [EC:3.2.1.4] synonym: "beta-1,4-endoglucan hydrolase activity" EXACT [EC:3.2.1.4] synonym: "beta-1,4-glucanase activity" BROAD [EC:3.2.1.4] synonym: "carboxymethyl cellulase activity" NARROW [EC:3.2.1.4] synonym: "celluase A" RELATED [EC:3.2.1.4] synonym: "celludextrinase activity" EXACT [EC:3.2.1.4] synonym: "cellulase A 3" RELATED [EC:3.2.1.4] synonym: "cellulosin AP" RELATED [EC:3.2.1.4] synonym: "endo-1,4-beta-D-glucanase activity" EXACT [EC:3.2.1.4] synonym: "endo-1,4-beta-D-glucanohydrolase activity" EXACT [EC:3.2.1.4] synonym: "endo-1,4-beta-glucanase activity" EXACT [EC:3.2.1.4] synonym: "endoglucanase activity" EXACT [EC:3.2.1.4] synonym: "endoglucanase D" RELATED [EC:3.2.1.4] synonym: "pancellase SS" RELATED [EC:3.2.1.4] xref: EC:3.2.1.4 xref: GO:0008810 xref: MetaCyc:3.2.1.4-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0002155 name: chloramphenicol O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate." [EC:2.3.1.28] subset: gosubset_prok synonym: "acetyl-CoA:chloramphenicol 3-O-acetyltransferase activity" EXACT [EC:2.3.1.28] synonym: "CAT I" RELATED [EC:2.3.1.28] synonym: "CAT II" RELATED [EC:2.3.1.28] synonym: "CAT III" RELATED [EC:2.3.1.28] synonym: "chloramphenicol acetylase activity" EXACT [EC:2.3.1.28] synonym: "chloramphenicol acetyltransferase activity" EXACT [EC:2.3.1.28] synonym: "chloramphenicol transacetylase activity" EXACT [EC:2.3.1.28] xref: EC:2.3.1.28 xref: GO:0008811 xref: MetaCyc:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0002156 name: choline dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: choline + acceptor = betaine aldehyde + reduced acceptor." [EC:1.1.99.1] subset: gosubset_prok synonym: "choline oxidase activity" BROAD [EC:1.1.99.1] synonym: "choline-cytochrome c reductase activity" RELATED [EC:1.1.99.1] synonym: "choline:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.1] synonym: "choline:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.1] synonym: "choline:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.1] xref: EC:1.1.99.1 xref: GO:0008812 xref: MetaCyc:CHD-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0002157 name: chorismate lyase activity namespace: molecular_function def: "Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate." [EC:4.1.3.40, IMG:00552, MetaCyc:CHORPYRLY-RXN] subset: gosubset_prok synonym: "4-hydroxybenzoate synthetase activity" EXACT [] synonym: "chorismate pyruvate lyase activity" EXACT [] synonym: "chorismate pyruvate-lyase (4-hydroxybenzoate-forming) activity" EXACT [EC:4.1.3.40] synonym: "CL" RELATED [EC:4.1.3.40] synonym: "CPL" RELATED [EC:4.1.3.40] synonym: "UbiC" RELATED [EC:4.1.3.40] xref: EC:4.1.3.40 xref: GO:0008813 xref: MetaCyc:CHORPYRLY-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0002158 name: citrate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA." [EC:2.8.3.10] subset: gosubset_prok synonym: "acetyl-CoA:citrate CoA-transferase activity" EXACT [EC:2.8.3.10] xref: EC:2.8.3.10 xref: GO:0008814 xref: MetaCyc:CITTRANS-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0002159 name: citrate (pro-3S)-lyase activity namespace: molecular_function def: "Catalysis of the reaction: citrate = acetate + oxaloacetate." [EC:4.1.3.6] subset: gosubset_prok synonym: "citrase activity" EXACT [EC:4.1.3.6] synonym: "citratase activity" EXACT [EC:4.1.3.6] synonym: "citrate aldolase activity" EXACT [EC:4.1.3.6] synonym: "citrate lyase activity" EXACT [] synonym: "citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]" RELATED [EC:4.1.3.6] synonym: "citrate oxaloacetate-lyase activity" EXACT [EC:4.1.3.6] synonym: "citric aldolase activity" EXACT [EC:4.1.3.6] synonym: "citridesmolase activity" EXACT [EC:4.1.3.6] synonym: "citritase activity" EXACT [EC:4.1.3.6] xref: EC:4.1.3.6 xref: GO:0008815 xref: MetaCyc:CITLY-RXN xref: Reactome:26375 is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0002160 name: citryl-CoA lyase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate." [EC:4.1.3.34] subset: gosubset_prok synonym: "(3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.34] synonym: "(3S)-citryl-CoA oxaloacetate-lyase activity" EXACT [EC:4.1.3.34] xref: EC:4.1.3.34 xref: GO:0008816 xref: MetaCyc:CITRYLY-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0002161 name: cob(I)yrinic acid a,c-diamide adenosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin." [EC:2.5.1.17] subset: gosubset_prok synonym: "aquacob(I)alamin adenosyltransferase activity" EXACT [EC:2.5.1.17] synonym: "aquocob(I)alamin vitamin B12s adenosyltransferase activity" RELATED [EC:2.5.1.17] synonym: "ATP:cob(I)alamin Co-beta-adenosyltransferase activity" EXACT [EC:2.5.1.17] synonym: "ATP:cob(I)alamin cobeta-adenosyltransferase activity" EXACT [EC:2.5.1.17] synonym: "ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity" EXACT [EC:2.5.1.17] synonym: "ATP:corrinoid adenosyltransferase activity" EXACT [EC:2.5.1.17] synonym: "cob(I)alamin adenosyltransferase activity" EXACT [] synonym: "CobA" RELATED [EC:2.5.1.17] synonym: "vitamin B12s adenosyltransferase activity" EXACT [EC:2.5.1.17] xref: EC:2.5.1.17 xref: GO:0008817 xref: MetaCyc:COBALADENOSYLTRANS-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0002162 name: cobalamin 5'-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP." [MetaCyc:COBALAMIN5PSYN-RXN] subset: gosubset_prok xref: GO:0008818 xref: MetaCyc:COBALAMIN5PSYN-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0002163 name: cobinamide kinase activity namespace: molecular_function def: "Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate." [http://www.mblab.gla.ac.uk/, PMID:1655696] subset: gosubset_prok xref: EC:2.7.1.- xref: GO:0008819 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002164 name: cobinamide phosphate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: adenosylcobinamide-phosphate + GTP = adenosylcobinamide-GDP + diphosphate." [MetaCyc:COBINPGUANYLYLTRANS-RXN] subset: gosubset_prok synonym: "GTP:cobinamide phosphate guanylyltransferase activity" EXACT [] xref: GO:0008820 xref: MetaCyc:COBINPGUANYLYLTRANS-RXN is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0002165 name: crossover junction endodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)." [EC:3.1.22.4] synonym: "crossover junction endoribonuclease activity" EXACT [] synonym: "cruciform-cutting endonuclease activity" EXACT [EC:3.1.22.-] synonym: "endo X3" RELATED [EC:3.1.22.4] synonym: "Endo X3 activity" NARROW [EC:3.1.22.-] synonym: "endodeoxyribonuclease RUS activity" EXACT [] synonym: "endonuclease RuvC activity" NARROW [EC:3.1.22.-] synonym: "endonuclease VII activity" NARROW [EC:3.1.22.-] synonym: "endonuclease X3 activity" NARROW [EC:3.1.22.-] synonym: "Hje endonuclease activity" EXACT [EC:3.1.22.-] synonym: "Holliday junction endonuclease CCE1 activity" NARROW [EC:3.1.22.-] synonym: "Holliday junction nuclease activity" EXACT [EC:3.1.22.-] synonym: "Holliday junction resolvase activity" NARROW [EC:3.1.22.-] synonym: "Holliday junction-cleaving endonuclease activity" EXACT [EC:3.1.22.-] synonym: "Holliday junction-resolving endoribonuclease activity" NARROW [EC:3.1.22.-] synonym: "resolving enzyme CCE1 activity" NARROW [EC:3.1.22.-] synonym: "RusA endonuclease activity" NARROW [EC:3.1.22.-] synonym: "RusA holliday junction resolvase" NARROW [EC:3.1.22.4] synonym: "RusA Holliday junction resolvase activity" NARROW [EC:3.1.22.-] synonym: "RuvC endonuclease activity" NARROW [EC:3.1.22.-] synonym: "SpCCe1 holliday junction resolvase" NARROW [EC:3.1.22.4] synonym: "SpCCe1 Holliday junction resolvase activity" NARROW [EC:3.1.22.-] xref: EC:3.1.22.- xref: EC:3.1.22.4 xref: GO:0008821 xref: GO:0008844 xref: MetaCyc:3.1.22.4-RXN is_a: CCO:F0003447 ! endodeoxyribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0002166 name: cupric reductase activity namespace: molecular_function xref: EC:1.16.1.- xref: GO:0008823 is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0002167 name: cyanate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: cyanate (NCO-) + H2O = carbamate (H2N-CO-O-)." [EC:4.2.1.104] comment: Note that this function was formerly EC:4.3.99.1. subset: gosubset_prok synonym: "carbamate hydro-lyase activity" EXACT [EC:4.2.1.104] synonym: "cyanase activity" EXACT [] synonym: "cyanate aminohydrolase activity" EXACT [EC:4.2.1.104] synonym: "cyanate C-N-lyase activity" EXACT [EC:4.2.1.104] synonym: "cyanate hydrolase activity" EXACT [EC:4.2.1.104] synonym: "cyanate lyase activity" EXACT [] xref: EC:4.2.1.104 xref: GO:0008824 xref: MetaCyc:4.3.99.1-RXN xref: UM-BBD_enzymeID:e0396 is_a: CCO:F0003405 ! carbon-nitrogen lyase activity [Term] id: CCO:F0002168 name: cyclopropane-fatty-acyl-phospholipid synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid." [EC:2.1.1.79] subset: gosubset_prok synonym: "CFA synthase activity" EXACT [EC:2.1.1.79] synonym: "cyclopropane fatty acid synthase activity" EXACT [EC:2.1.1.79] synonym: "cyclopropane fatty acid synthetase activity" EXACT [EC:2.1.1.79] synonym: "cyclopropane synthase activity" EXACT [EC:2.1.1.79] synonym: "cyclopropane synthetase activity" BROAD [EC:2.1.1.79] synonym: "S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)" EXACT [EC:2.1.1.79] synonym: "unsaturated-phospholipid methyltransferase activity" BROAD [EC:2.1.1.79] xref: EC:2.1.1.79 xref: GO:0008825 xref: MetaCyc:2.1.1.79-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0002169 name: cysteine sulfinate desulfinase activity namespace: molecular_function def: "Catalysis of the reaction: 3-sulfinoalanine = L-alanine + SO3(2-)." [MetaCyc:RXN0-279] synonym: "cysteine sulphinate desulphinase activity" EXACT [] xref: EC:4.4.1.- xref: GO:0008826 xref: MetaCyc:RXN0-279 is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0002170 name: cytochrome o ubiquinol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2R; cytochrome O is the electron acceptor." [GOC:mah, MetaCyc:CYT-UBIQUINOL-OXID-RXN] subset: gosubset_prok xref: EC:1.10.3.- xref: GO:0008827 is_a: CCO:F0002522 ! heme-copper terminal oxidase activity is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0002171 name: dATP pyrophosphohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate." [MetaCyc:RXN0-384] subset: gosubset_prok xref: EC:3.6.1.- xref: GO:0008828 xref: MetaCyc:RXN0-384 is_a: CCO:F0006737 ! nucleoside-triphosphate diphosphatase activity [Term] id: CCO:F0002172 name: dCTP deaminase activity namespace: molecular_function def: "Catalysis of the reaction: dCTP + H2O = dUTP + NH3." [EC:3.5.4.13] subset: gosubset_prok synonym: "5-methyl-dCTP deaminase activity" EXACT [EC:3.5.4.13] synonym: "dCTP aminohydrolase activity" EXACT [EC:3.5.4.13] synonym: "deoxycytidine triphosphate deaminase activity" EXACT [EC:3.5.4.13] xref: EC:3.5.4.13 xref: GO:0008829 xref: MetaCyc:DCTP-DEAM-RXN xref: Reactome:26405 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0002173 name: dTDP-4-dehydrorhamnose 3,5-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose." [EC:5.1.3.13] subset: gosubset_prok synonym: "dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase activity" EXACT [EC:5.1.3.13] synonym: "dTDP-4-keto-6-deoxyglucose 3,5-epimerase activity" EXACT [EC:5.1.3.13] synonym: "dTDP-L-rhamnose synthetase activity" EXACT [EC:5.1.3.13] synonym: "TDP-4-keto-L-rhamnose-3,5-epimerase activity" EXACT [EC:5.1.3.13] synonym: "TDP-4-ketorhamnose 3,5-epimerase activity" EXACT [EC:5.1.3.13] synonym: "thymidine diphospho-4-ketorhamnose 3,5-epimerase activity" RELATED [EC:5.1.3.13] xref: EC:5.1.3.13 xref: GO:0008830 xref: MetaCyc:DTDPDEHYDRHAMEPIM-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0002174 name: dTDP-4-dehydrorhamnose reductase activity namespace: molecular_function def: "Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+." [EC:1.1.1.133] subset: gosubset_prok synonym: "dTDP-4-keto-L-rhamnose reductase activity" EXACT [EC:1.1.1.133] synonym: "dTDP-4-ketorhamnose reductase activity" EXACT [EC:1.1.1.133] synonym: "dTDP-6-deoxy-L-mannose dehydrogenase activity" EXACT [EC:1.1.1.133] synonym: "dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.133] synonym: "reductase, thymidine diphospho-4-ketorhamnose" EXACT [EC:1.1.1.133] synonym: "TDP-4-keto-rhamnose reductase activity" EXACT [EC:1.1.1.133] synonym: "thymidine diphospho-4-ketorhamnose reductase activity" EXACT [EC:1.1.1.133] xref: EC:1.1.1.133 xref: GO:0008831 xref: MetaCyc:DTDPDEHYRHAMREDUCT-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002175 name: dGTPase activity namespace: molecular_function def: "Catalysis of the reaction: dGTP + H2O = deoxyguanosine + triphosphate." [EC:3.1.5.1] subset: gosubset_prok synonym: "deoxy-GTPase activity" EXACT [EC:3.1.5.1] synonym: "deoxyguanosine 5-triphosphate triphosphohydrolase activity" EXACT [EC:3.1.5.1] synonym: "deoxyguanosine triphosphatase activity" EXACT [EC:3.1.5.1] synonym: "deoxyguanosine triphosphate triphosphohydrolase activity" EXACT [EC:3.1.5.1] synonym: "deoxyguanosinetriphosphate triphosphohydrolase activity" EXACT [] synonym: "dGTP triphosphohydrolase activity" EXACT [EC:3.1.5.1] xref: EC:3.1.5.1 xref: GO:0008832 xref: MetaCyc:DGTPTRIPHYDRO-RXN is_a: CCO:F0003363 ! triphosphoric monoester hydrolase activity [Term] id: CCO:F0002176 name: deoxyribonuclease IV (phage-T4-induced) activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products." [EC:3.1.21.2] subset: gosubset_prok synonym: "deoxriboendonuclease activity" EXACT [EC:3.1.21.2] synonym: "deoxyribonuclease IV (phage T4-induced) activity" EXACT [EC:3.1.21.2] synonym: "DNA-adenine-transferase activity" EXACT [EC:3.1.21.2] synonym: "E. coli endonuclease IV" RELATED [EC:3.1.21.2] synonym: "endodeoxyribonuclease IV (phage T(4)-induced) activity" EXACT [EC:3.1.21.2] synonym: "endodeoxyribonuclease IV (phage T4-induced) activity" EXACT [EC:3.1.21.2] synonym: "endonuclease II" RELATED [EC:3.1.21.2] synonym: "endonuclease IV activity" RELATED [EC:3.1.21.2] synonym: "Escherichia coli endonuclease II" RELATED [EC:3.1.21.2] synonym: "redoxyendonuclease activity" EXACT [EC:3.1.21.2] xref: EC:3.1.21.2 xref: GO:0008833 xref: MetaCyc:3.1.21.2-RXN is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002177 name: di-trans,poly-cis-decaprenylcistransferase activity namespace: molecular_function def: "Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate." [EC:2.5.1.31] subset: gosubset_prok synonym: "bactoprenyl-diphosphate synthase activity" RELATED [EC:2.5.1.31] synonym: "di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity" EXACT [EC:2.5.1.31] synonym: "di-trans,poly-cis-undecaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.31] synonym: "undecaprenyl diphosphate synthase activity" EXACT [] synonym: "undecaprenyl diphosphate synthetase activity" EXACT [EC:2.5.1.31] synonym: "undecaprenyl pyrophosphate synthase activity" EXACT [EC:2.5.1.31] synonym: "undecaprenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.31] synonym: "undecaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.31] synonym: "UPP synthetase activity" EXACT [EC:2.5.1.31] xref: EC:2.5.1.31 xref: GO:0008834 xref: MetaCyc:DECAPCISTRANSFER-RXN is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0002178 name: diaminohydroxyphosphoribosylaminopyrimidine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H2O = 5-amino-6-(5-phosphoribosylamino)uracil + NH3." [EC:3.5.4.26] subset: gosubset_prok synonym: "2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity" EXACT [] synonym: "2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity" EXACT [EC:3.5.4.26] synonym: "2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity" EXACT [EC:3.5.4.26] xref: EC:3.5.4.26 xref: GO:0008485 xref: GO:0008835 xref: MetaCyc:RIBOFLAVINSYNDEAM-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0002179 name: diaminopimelate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: meso-2,6-diaminoheptanedioate = L-lysine + CO2." [EC:4.1.1.20] subset: gosubset_prok synonym: "DAP decarboxylase activity" EXACT [EC:4.1.1.20] synonym: "DAP-decarboxylase activity" EXACT [EC:4.1.1.20] synonym: "diaminopimelic acid decarboxylase activity" EXACT [EC:4.1.1.20] synonym: "meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming)" EXACT [EC:4.1.1.20] synonym: "meso-2,6-diaminoheptanedioate carboxy-lyase activity" EXACT [EC:4.1.1.20] synonym: "meso-diaminopimelate decarboxylase activity" EXACT [EC:4.1.1.20] xref: EC:4.1.1.20 xref: GO:0008836 xref: MetaCyc:DIAMINOPIMDECARB-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002180 name: diaminopimelate epimerase activity namespace: molecular_function def: "Catalysis of the reaction: LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate." [EC:5.1.1.7] subset: gosubset_prok synonym: "LL-2,6-diaminoheptanedioate 2-epimerase activity" EXACT [EC:5.1.1.7] xref: EC:5.1.1.7 xref: GO:0008837 xref: MetaCyc:DIAMINOPIMEPIM-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0002181 name: diaminopropionate ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3." [EC:4.3.1.15] subset: gosubset_prok synonym: "2,3-diaminopropionate ammonia-lyase (adding H2O; pyruvate-forming)" EXACT [EC:4.3.1.15] synonym: "2,3-diaminopropionate ammonia-lyase activity" EXACT [EC:4.3.1.15] synonym: "alpha,beta-diaminopropionate ammonia-lyase activity" EXACT [EC:4.3.1.15] synonym: "diaminopropionatase activity" EXACT [EC:4.3.1.15] xref: EC:4.3.1.15 xref: GO:0008838 xref: MetaCyc:4.3.1.15-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0002182 name: dihydrodipicolinate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3,4,5-tetrahydrodipicolinate + NADP+ = 2,3-dihydrodipicolinate + NADPH + H+." [EC:1.3.1.26] subset: gosubset_prok synonym: "2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.26] synonym: "dihydrodipicolinic acid reductase activity" EXACT [EC:1.3.1.26] xref: EC:1.3.1.26 xref: GO:0008839 xref: MetaCyc:DIHYDROPICRED-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002183 name: dihydrodipicolinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate-4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O." [EC:4.2.1.52] subset: gosubset_prok synonym: "DHDPS activity" EXACT [EC:4.2.1.52] synonym: "dihydrodipicolinate synthetase activity" EXACT [EC:4.2.1.52] synonym: "dihydrodipicolinic acid synthase activity" EXACT [EC:4.2.1.52] synonym: "dihydropicolinate synthetase activity" EXACT [EC:4.2.1.52] synonym: "L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)" EXACT [EC:4.2.1.52] synonym: "L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]" RELATED [EC:4.2.1.52] xref: EC:4.2.1.52 xref: GO:0008840 xref: MetaCyc:DIHYDRODIPICSYN-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002184 name: dihydrofolate synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate." [EC:6.3.2.12] subset: gosubset_prok synonym: "7,8-dihydrofolate synthetase activity" EXACT [EC:6.3.2.12] synonym: "7,8-dihydropteroate:L-glutamate ligase (ADP) activity" EXACT [EC:6.3.2.12] synonym: "7,8-dihydropteroate:L-glutamate ligase (ADP-forming)" EXACT [EC:6.3.2.12] synonym: "DHFS activity" EXACT [EC:6.3.2.12] synonym: "dihydrofolate synthetase activity" EXACT [EC:6.3.2.12] synonym: "dihydrofolate synthetase-folylpolyglutamate synthetase activity" EXACT [EC:6.3.2.12] synonym: "dihydropteroate:L-glutamate ligase (ADP-forming) activity" EXACT [EC:6.3.2.12] synonym: "FHFS activity" EXACT [EC:6.3.2.12] synonym: "FHFS/FPGS activity" EXACT [EC:6.3.2.12] synonym: "folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase activity" EXACT [EC:6.3.2.12] synonym: "H(2)-folate synthetase activity" EXACT [EC:6.3.2.12] synonym: "H2-folate synthetase activity" EXACT [EC:6.3.2.12] xref: EC:6.3.2.12 xref: GO:0008841 xref: MetaCyc:DIHYDROFOLATESYNTH-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0002185 name: diphosphate-purine nucleoside kinase activity namespace: molecular_function def: "Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide." [EC:2.7.1.143] synonym: "diphosphate-dependent nucleoside kinase activity" EXACT [EC:2.7.1.143] synonym: "diphosphate:purine nucleoside phosphotransferase activity" EXACT [EC:2.7.1.143] synonym: "pyrophosphate-dependent nucleoside kinase activity" EXACT [EC:2.7.1.143] synonym: "pyrophosphate-purine nucleoside kinase activity" EXACT [EC:2.7.1.143] xref: EC:2.7.1.143 xref: GO:0008842 xref: MetaCyc:2.7.1.143-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004129 ! nucleoside kinase activity [Term] id: CCO:F0002186 name: endochitinase activity namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal 1,4-beta-linkages of N-acetyl-D-glucosamine polymers of chitin and chitodextrins." [EC:3.2.1.14] xref: GO:0008843 is_a: CCO:F0000952 ! chitinase activity [Term] id: CCO:F0002187 name: endopeptidase La activity namespace: molecular_function def: "Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP." [EC:3.4.21.53] subset: gosubset_prok synonym: "ATP-dependent lon proteinase" NARROW [EC:3.4.21.53] synonym: "ATP-dependent protease La activity" EXACT [EC:3.4.21.53] synonym: "ATP-dependent serine proteinase activity" RELATED [EC:3.4.21.53] synonym: "Escherichia coli proteinase La" RELATED [EC:3.4.21.53] synonym: "Escherichia coli serine proteinase La" RELATED [EC:3.4.21.53] synonym: "gene lon protease activity" EXACT [EC:3.4.21.53] synonym: "gene lon proteins" RELATED [EC:3.4.21.53] synonym: "lon proteinase" NARROW [EC:3.4.21.53] synonym: "PIM1 protease activity" EXACT [EC:3.4.21.53] synonym: "PIM1 proteinase activity" EXACT [EC:3.4.21.53] synonym: "protease La" RELATED [EC:3.4.21.53] synonym: "proteinase La" RELATED [EC:3.4.21.53] synonym: "serine protease La" RELATED [EC:3.4.21.53] xref: EC:3.4.21.53 xref: GO:0008846 xref: MetaCyc:3.4.21.53-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0002188 name: Enterobacter ribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates." [EC:3.1.27.6] subset: gosubset_prok synonym: "enterobacter ribonuclease activity" EXACT [EC:3.1.27.6] synonym: "Enterobacter RNase activity" EXACT [] xref: EC:3.1.27.6 xref: GO:0008847 xref: MetaCyc:3.1.27.6-RXN is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0002189 name: enterochelin esterase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the enterochelin moiety of ferric-enterochelin to yield ultimately three molecules of N-2,3-dihydroxybenzoylserine." [PMID:4565531] synonym: "enterobactin esterase activity" EXACT [] xref: GO:0008849 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0002190 name: ethanolamine ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: ethanolamine = acetaldehyde + NH3." [EC:4.3.1.7] subset: gosubset_prok synonym: "ethanolamine ammonia-lyase (acetaldehyde-forming) activity" EXACT [EC:4.3.1.7] synonym: "ethanolamine deaminase activity" EXACT [EC:4.3.1.7] xref: EC:4.3.1.7 xref: GO:0008851 xref: MetaCyc:ETHAMLY-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0002191 name: exodeoxyribonuclease I activity namespace: molecular_function def: "Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides." [EC:3.1.11.1] subset: gosubset_prok synonym: "E. coli exonuclease I activity" NARROW [EC:3.1.11.1] synonym: "E.coli exonuclease I" RELATED [EC:3.1.11.1] synonym: "Escherichia coli exonuclease I" RELATED [EC:3.1.11.1] synonym: "exonuclease I activity" RELATED [EC:3.1.11.1] xref: EC:3.1.11.1 xref: GO:0008852 xref: MetaCyc:3.1.11.1-RXN is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002192 name: exodeoxyribonuclease III activity namespace: molecular_function def: "Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides." [EC:3.1.11.2] subset: gosubset_prok synonym: "E. coli exonuclease III activity" NARROW [EC:3.1.11.2] synonym: "E.coli exonuclease III" RELATED [EC:3.1.11.2] synonym: "endoribonuclease III" RELATED [EC:3.1.11.2] synonym: "Escherichia coli exonuclease III" RELATED [EC:3.1.11.2] synonym: "exonuclease III activity" EXACT [EC:3.1.11.2] xref: EC:3.1.11.2 xref: GO:0008853 xref: MetaCyc:3.1.11.2-RXN is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002193 name: exodeoxyribonuclease V activity namespace: molecular_function def: "Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides." [EC:3.1.11.5] subset: gosubset_prok synonym: "E. coli exonuclease V activity" NARROW [EC:3.1.11.5] synonym: "E.coli exonuclease V" RELATED [EC:3.1.11.5] synonym: "Escherichia coli exonuclease V" RELATED [EC:3.1.11.5] synonym: "exonuclease V activity" EXACT [EC:3.1.11.5] synonym: "gene recBC DNase activity" EXACT [EC:3.1.11.5] synonym: "gene recBC endoenzyme" RELATED [EC:3.1.11.5] synonym: "gene recBCD enzymes" RELATED [EC:3.1.11.5] synonym: "RecBC deoxyribonuclease activity" EXACT [EC:3.1.11.5] xref: EC:3.1.11.5 xref: GO:0008854 xref: MetaCyc:3.1.11.5-RXN is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002194 name: exodeoxyribonuclease VII activity namespace: molecular_function def: "Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides." [EC:3.1.11.6] subset: gosubset_prok synonym: "E. coli exonuclease VII activity" NARROW [EC:3.1.11.6] synonym: "E.coli exonuclease VII" RELATED [EC:3.1.11.6] synonym: "endodeoxyribonuclease VII" RELATED [EC:3.1.11.6] synonym: "Escherichia coli exonuclease VII" RELATED [EC:3.1.11.6] synonym: "exonuclease VII activity" EXACT [EC:3.1.11.6] xref: EC:3.1.11.6 xref: GO:0008855 xref: MetaCyc:3.1.11.6-RXN is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002195 name: exodeoxyribonuclease X activity namespace: molecular_function def: "Catalysis of the reaction: Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes." [EC:3.1.22.5] synonym: "deoxyribonuclease X activity" EXACT [EC:3.1.22.5] synonym: "Escherichia coli endodeoxyribonuclease activity" RELATED [EC:3.1.22.5] synonym: "Escherichia coli endodeoxyribonuclease X activity" NARROW [EC:3.1.22.5] xref: EC:3.1.11.- xref: GO:0008856 is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002196 name: exonuclease IX activity namespace: molecular_function subset: gosubset_prok xref: GO:0008857 is_a: CCO:F0000923 ! exonuclease activity [Term] id: CCO:F0002197 name: exonuclease VIII activity namespace: molecular_function xref: EC:3.1.11.- xref: GO:0008858 is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002198 name: exoribonuclease II activity namespace: molecular_function def: "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction." [EC:3.1.13.1, ISBN:0198547684] subset: gosubset_prok synonym: "5'-exoribonuclease activity" EXACT [EC:3.1.13.1] synonym: "BN ribonuclease activity" EXACT [EC:3.1.13.1] synonym: "Escherichia coli exo-RNase II" RELATED [EC:3.1.13.1] synonym: "ribonuclease II activity" EXACT [EC:3.1.13.1] synonym: "ribonuclease Q" RELATED [EC:3.1.13.1] synonym: "RNase II" RELATED [EC:3.1.13.1] synonym: "RNase II activity" EXACT [] xref: EC:3.1.13.1 xref: GO:0008859 xref: MetaCyc:3.1.13.1-RXN is_a: CCO:F0001875 ! 3'-5' exonuclease activity is_a: CCO:F0003454 ! exoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002199 name: ferredoxin-NAD+ reductase activity namespace: molecular_function def: "Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+." [EC:1.18.1.3] subset: gosubset_prok synonym: "ferredoxin-linked NAD reductase activity" EXACT [EC:1.18.1.3] synonym: "ferredoxin-NAD reductase activity" EXACT [] synonym: "ferredoxin-nicotinamide adenine dinucleotide reductase activity" EXACT [EC:1.18.1.3] synonym: "ferredoxin:NAD+ oxidoreductase activity" EXACT [EC:1.18.1.3] synonym: "NAD-ferredoxin reductase activity" EXACT [EC:1.18.1.3] synonym: "NADH flavodoxin oxidoreductase activity" EXACT [EC:1.18.1.3] synonym: "NADH-ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.3] synonym: "NADH-ferredoxin reductase activity" EXACT [EC:1.18.1.3] synonym: "NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)" EXACT [EC:1.18.1.3] synonym: "NADH-ferredoxinTOL reductase (component of toluene dioxygenase)" EXACT [EC:1.18.1.3] synonym: "NADH2-ferredoxin oxidoreductase activity" EXACT [EC:1.18.1.3] synonym: "reductase, reduced nicotinamide adenine dinucleotide-ferredoxin" EXACT [EC:1.18.1.3] xref: EC:1.18.1.3 xref: GO:0008860 xref: MetaCyc:FERREDOXIN--NAD(+)-REDUCTASE-RXN is_a: CCO:F0002273 ! ferredoxin reductase activity [Term] id: CCO:F0002200 name: formate C-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate." [EC:2.3.1.54] subset: gosubset_prok synonym: "acetyl-CoA:formate C-acetyltransferase activity" EXACT [EC:2.3.1.54] synonym: "formate acetyltransferase activity" EXACT [EC:2.3.1.54] synonym: "pyruvate formate-lyase activity" EXACT [EC:2.3.1.54] synonym: "pyruvic formate-lyase activity" EXACT [EC:2.3.1.54] xref: EC:2.3.1.54 xref: GO:0008861 xref: MetaCyc:PYRUVFORMLY-RXN is_a: CCO:F0003163 ! C-acetyltransferase activity [Term] id: CCO:F0002201 name: formate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: formate + NAD+ = CO2 + NADH + H+." [EC:1.2.1.2] subset: gosubset_prok synonym: "FDH I" RELATED [EC:1.2.1.2] synonym: "FDH II" RELATED [EC:1.2.1.2] synonym: "formate benzyl-viologen oxidoreductase" EXACT [EC:1.2.1.2] synonym: "formate dehydrogenase (NAD)" EXACT [EC:1.2.1.2] synonym: "formate hydrogenlyase" EXACT [EC:1.2.1.2] synonym: "formate-NAD oxidoreductase" EXACT [EC:1.2.1.2] synonym: "formate:NAD+ oxidoreductase" EXACT [EC:1.2.1.2] synonym: "formic acid dehydrogenase" EXACT [EC:1.2.1.2] synonym: "formic hydrogen-lyase" EXACT [EC:1.2.1.2] synonym: "N-FDH" RELATED [EC:1.2.1.2] synonym: "NAD-dependent formate dehydrogenase" EXACT [EC:1.2.1.2] synonym: "NAD-formate dehydrogenase" EXACT [EC:1.2.1.2] synonym: "NAD-linked formate dehydrogenase" EXACT [EC:1.2.1.2] xref: EC:1.2.1.2 xref: GO:0008863 xref: GO:0018476 xref: MetaCyc:FORMATEDEHYDROG-RXN xref: UM-BBD_enzymeID:e0080 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002202 name: formyltetrahydrofolate deformylase activity namespace: molecular_function def: "Catalysis of the reaction: 10-formyltetrahydrofolate + H2O = formate + tetrahydrofolate." [EC:3.5.1.10] subset: gosubset_prok synonym: "10-formyltetrahydrofolate amidohydrolase activity" EXACT [EC:3.5.1.10] synonym: "formyl-FH(4) hydrolase activity" EXACT [EC:3.5.1.10] synonym: "formyltetrahydrofolate hydrolase activity" EXACT [EC:3.5.1.10] xref: EC:3.5.1.10 xref: GO:0008864 xref: MetaCyc:FORMYLTHFDEFORMYL-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002203 name: fructokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate." [EC:2.7.1.4] subset: gosubset_prok synonym: "ATP:D-fructose 6-phosphotransferase activity" EXACT [EC:2.7.1.4] synonym: "D-fructokinase activity" EXACT [EC:2.7.1.4] synonym: "D-fructose(D-mannose)kinase activity" EXACT [EC:2.7.1.4] synonym: "fructokinase (phosphorylating)" EXACT [EC:2.7.1.4] xref: EC:2.7.1.4 xref: GO:0008865 xref: MetaCyc:FRUCTOKINASE-RXN is_a: CCO:F0000807 ! hexokinase activity [Term] id: CCO:F0002204 name: fructuronate reductase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannonate + NAD+ = D-fructuronate + NADH + H+." [EC:1.1.1.57] subset: gosubset_prok synonym: "D-mannonate dehydrogenase activity" EXACT [EC:1.1.1.57] synonym: "D-mannonate oxidoreductase activity" EXACT [EC:1.1.1.57] synonym: "D-mannonate:NAD oxidoreductase activity" EXACT [EC:1.1.1.57] synonym: "D-mannonate:NAD+ 5-oxidoreductase activity" EXACT [EC:1.1.1.57] synonym: "mannonate oxidoreductase activity" EXACT [EC:1.1.1.57] synonym: "mannonic dehydrogenase activity" EXACT [EC:1.1.1.57] xref: EC:1.1.1.57 xref: GO:0008866 xref: MetaCyc:MANNONOXIDOREDUCT-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002205 name: galactarate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O." [EC:4.2.1.42] subset: gosubset_prok synonym: "D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)" EXACT [EC:4.2.1.42] synonym: "D-galactarate hydro-lyase activity" EXACT [EC:4.2.1.42] xref: EC:4.2.1.42 xref: GO:0008867 xref: MetaCyc:GALACTARDEHYDRA-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002206 name: galactitol-1-phosphate 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: galactitol-1-phosphate + NAD+ = L-tagatose 6-phosphate + NADH + H+." [EC:1.1.1.251] subset: gosubset_prok synonym: "galactitol-1-phosphate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.251] xref: EC:1.1.1.251 xref: GO:0008868 xref: MetaCyc:1.1.1.251-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002207 name: galactonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O." [EC:4.2.1.6] subset: gosubset_prok synonym: "D-galactonate dehydrase activity" EXACT [EC:4.2.1.6] synonym: "D-galactonate dehydratase activity" EXACT [EC:4.2.1.6] synonym: "D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)" EXACT [EC:4.2.1.6] synonym: "D-galactonate hydro-lyase activity" EXACT [EC:4.2.1.6] xref: EC:4.2.1.6 xref: GO:0008869 xref: MetaCyc:GALACTONDEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002208 name: galactoside O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside." [EC:2.3.1.18] subset: gosubset_prok synonym: "acetyl-CoA:beta-D-galactoside 6-acetyltransferase activity" EXACT [EC:2.3.1.18] synonym: "galactoside acetyltransferase activity" EXACT [EC:2.3.1.18] synonym: "thiogalactoside acetyltransferase activity" EXACT [EC:2.3.1.18] synonym: "thiogalactoside transacetylase activity" EXACT [EC:2.3.1.18] xref: EC:2.3.1.18 xref: GO:0008870 xref: MetaCyc:GALACTOACETYLTRAN-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0002209 name: aminoglycoside 2''-nucleotidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside." [EC:2.7.7.46, GOC:cb] subset: gosubset_prok synonym: "2''-aminoglycoside nucleotidyltransferase activity" EXACT [EC:2.7.7.46] synonym: "gentamicin 2''- adenylyltransferase activity" NARROW [EC:2.7.7.46] synonym: "gentamicin 2''-nucleotidyltransferase activity" NARROW [EC:2.7.7.46] synonym: "gentamycin 2''-nucleotidyltransferase activity" NARROW [EC:2.7.7.46] synonym: "NTP:gentamicin 2''-nucleotidyltransferase activity" NARROW [EC:2.7.7.46] xref: EC:2.7.7.46 xref: GO:0008871 xref: MetaCyc:2.7.7.46-RXN is_a: CCO:F0005512 ! aminoglycoside nucleotidyltransferase activity [Term] id: CCO:F0002210 name: glucarate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O." [EC:4.2.1.40] subset: gosubset_prok synonym: "D-glucarate dehydratase activity" EXACT [EC:4.2.1.40] synonym: "D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)" EXACT [EC:4.2.1.40] synonym: "D-glucarate hydro-lyase activity" EXACT [EC:4.2.1.40] xref: EC:4.2.1.40 xref: GO:0008872 xref: MetaCyc:GLUCARDEHYDRA-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002211 name: gluconate 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.215] subset: gosubset_prok synonym: "2-keto-D-gluconate reductase activity" EXACT [EC:1.1.1.215] synonym: "2-ketogluconate reductase activity" EXACT [EC:1.1.1.215] synonym: "D-gluconate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.215] xref: EC:1.1.1.215 xref: GO:0008873 xref: MetaCyc:1.1.1.215-RXN is_a: CCO:F0002213 ! gluconate dehydrogenase activity [Term] id: CCO:F0002212 name: gluconate 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.69] subset: gosubset_prok synonym: "5-keto-D-gluconate 5-reductase activity" EXACT [EC:1.1.1.69] synonym: "5-keto-D-gluconate reductase" EXACT [EC:1.1.1.69] synonym: "5-ketogluconate 5-reductase activity" EXACT [EC:1.1.1.69] synonym: "5-ketogluconate reductase activity" EXACT [EC:1.1.1.69] synonym: "D-gluconate:NAD(P)+ 5-oxidoreductase" EXACT [EC:1.1.1.69] xref: EC:1.1.1.69 xref: GO:0008874 xref: MetaCyc:GLUCONATE-5-DEHYDROGENASE-RXN is_a: CCO:F0002213 ! gluconate dehydrogenase activity [Term] id: CCO:F0002213 name: gluconate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+." [EC:1.1.1.215, EC:1.1.1.69] subset: gosubset_prok xref: EC:1.1.1.- xref: GO:0008875 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002214 name: quinoprotein glucose dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol." [EC:1.1.5.2] comment: Note that this was EC:1.1.99.17. subset: gosubset_prok synonym: "D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase activity" EXACT [EC:1.1.5.2] synonym: "D-glucose:ubiquinone oxidoreductase activity" EXACT [EC:1.1.5.2] synonym: "glucose dehydrogenase (PQQ-dependent) activity" EXACT [EC:1.1.5.2] synonym: "glucose dehydrogenase (pyrroloquinoline-quinone) activity" EXACT [] synonym: "quinoprotein D-glucose dehydrogenase activity" EXACT [EC:1.1.5.2] xref: EC:1.1.5.2 xref: GO:0008876 xref: MetaCyc:GLUCDEHYDROG-RXN is_a: CCO:F0000763 ! glucose dehydrogenase activity is_a: CCO:F0003459 ! oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor [Term] id: CCO:F0002215 name: glucose-1-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose 1-phosphate + H2O = D-glucose + phosphate." [EC:3.1.3.10] subset: gosubset_prok synonym: "alpha-D-glucose-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.10] synonym: "D-glucose-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.10] xref: EC:3.1.3.10 xref: GO:0008877 xref: MetaCyc:GLUCOSE-1-PHOSPHAT-RXN is_a: CCO:F0004126 ! carbohydrate phosphatase activity [Term] id: CCO:F0002216 name: glucose-1-phosphate adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose." [EC:2.7.7.27] subset: gosubset_prok synonym: "adenosine diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] synonym: "adenosine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] synonym: "ADGase activity" EXACT [] synonym: "ADP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] synonym: "ADP-glucose diphosphorylase activity" EXACT [EC:2.7.7.27] synonym: "ADP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.27] synonym: "ADP-glucose synthase activity" EXACT [EC:2.7.7.27] synonym: "ADP-glucose synthetase activity" EXACT [EC:2.7.7.27] synonym: "ADP:alpha-D-glucose-1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.27] synonym: "ADPG pyrophosphorylase activity" EXACT [] synonym: "ATP:alpha-D-glucose-1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.27] synonym: "ATP:alpha-glucose-1-phosphate adenylyl transferase activity" EXACT [] synonym: "glucose 1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.27] xref: EC:2.7.7.27 xref: GO:0008878 xref: MetaCyc:GLUC1PADENYLTRANS-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002217 name: glucose-1-phosphate thymidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-glucose." [EC:2.7.7.24] subset: gosubset_prok synonym: "dTDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.24] synonym: "dTDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] synonym: "dTDP-glucose synthase activity" EXACT [EC:2.7.7.24] synonym: "dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.24] synonym: "glucose 1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.24] synonym: "TDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] synonym: "thymidine diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] synonym: "thymidine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.24] xref: EC:2.7.7.24 xref: GO:0008879 xref: MetaCyc:DTDPGLUCOSEPP-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002218 name: glucuronate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucuronate = D-fructuronate." [EC:5.3.1.12] subset: gosubset_prok synonym: "D-glucuronate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.12] synonym: "D-glucuronate isomerase activity" EXACT [EC:5.3.1.12] synonym: "D-glucuronate ketol-isomerase activity" EXACT [EC:5.3.1.12] synonym: "uronate isomerase activity" EXACT [EC:5.3.1.12] synonym: "uronic acid isomerase activity" EXACT [EC:5.3.1.12] synonym: "uronic isomerase activity" EXACT [EC:5.3.1.12] xref: EC:5.3.1.12 xref: GO:0008880 xref: MetaCyc:GLUCUROISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002219 name: glutamate racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate = D-glutamate." [EC:5.1.1.3] subset: gosubset_prok xref: EC:5.1.1.3 xref: GO:0008881 xref: MetaCyc:GLUTRACE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0002221 name: glutamyl-tRNA reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate 1-semialdehyde + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + NADPH + H+." [EC:1.2.1.70, MetaCyc:GLUTRNAREDUCT-RXN] subset: gosubset_prok synonym: "L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming)" EXACT [EC:1.2.1.70] xref: EC:1.2.1.70 xref: GO:0008883 xref: MetaCyc:GLUTRNAREDUCT-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002222 name: glutathionylspermidine amidase activity namespace: molecular_function def: "Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine." [EC:3.5.1.78] subset: gosubset_prok synonym: "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase activity" EXACT [EC:3.5.1.78] synonym: "glutathionylspermidine amidohydrolase (spermidine-forming) activity" EXACT [EC:3.5.1.78] synonym: "GSP amidase activity" EXACT [EC:3.5.1.78] xref: EC:3.5.1.78 xref: GO:0008884 xref: MetaCyc:GSPAMID-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002223 name: glutathionylspermidine synthase activity namespace: molecular_function def: "Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate." [EC:6.3.1.8] subset: gosubset_prok synonym: "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]" RELATED [EC:6.3.1.8] synonym: "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity" EXACT [EC:6.3.1.8] synonym: "glutathione:spermidine ligase (ADP-forming) activity" EXACT [EC:6.3.1.8] synonym: "glutathionylspermidine synthetase activity" EXACT [EC:6.3.1.8] synonym: "GSP synthetase activity" EXACT [EC:6.3.1.8] xref: EC:6.3.1.8 xref: GO:0008885 xref: MetaCyc:GSPSYN-RXN is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0002224 name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NADP+ + H2O = 3-phospho-D-glycerate + NADPH + H+." [EC:1.2.1.9] subset: gosubset_prok synonym: "D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase activity" EXACT [] synonym: "dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate)" BROAD [] synonym: "glyceraldehyde 3-phosphate dehydrogenase (NADP)" EXACT [] synonym: "glyceraldehyde phosphate dehydrogenase (NADP)" BROAD [] synonym: "glyceraldehyde-3-phosphate dehydrogenase (NADP)" EXACT [] synonym: "glyceraldehyde-3-phosphate:NADP reductase activity" EXACT [] synonym: "NADP-glyceraldehyde phosphate dehydrogenase" BROAD [] synonym: "NADP-glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [] synonym: "nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [] synonym: "triosephosphate dehydrogenase activity" BROAD [EC:1.2.1.9] xref: EC:1.2.1.9 xref: GO:0008886 xref: MetaCyc:1.2.1.9-RXN is_a: CCO:F0002279 ! glyceraldehyde-3-phosphate dehydrogenase activity [Term] id: CCO:F0002225 name: glycerate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (R)-glycerate = ADP + 3-phospho-(R)-glycerate." [EC:2.7.1.31] subset: gosubset_prok synonym: "ATP:(R)-glycerate 3-phosphotransferase activity" EXACT [EC:2.7.1.31] synonym: "ATP:D-glycerate 2-phosphotransferase activity" EXACT [EC:2.7.1.31] synonym: "D-glycerate 3-kinase activity" EXACT [EC:2.7.1.31] synonym: "D-glycerate kinase activity" EXACT [EC:2.7.1.31] synonym: "D-glyceric acid kinase activity" EXACT [EC:2.7.1.31] synonym: "GK" RELATED [EC:2.7.1.31] synonym: "glycerate kinase (phosphorylating)" EXACT [EC:2.7.1.31] synonym: "glycerate-3-kinase activity" EXACT [EC:2.7.1.31] xref: EC:2.7.1.31 xref: GO:0008887 xref: MetaCyc:GLY3KIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002226 name: glycerol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol + NAD+ = glycerone + NADH + H+." [EC:1.1.1.6] subset: gosubset_prok synonym: "NAD-linked glycerol dehydrogenase activity" EXACT [EC:1.1.1.6] xref: EC:1.1.1.6 xref: GO:0008888 xref: MetaCyc:GLYCDEH-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002227 name: glycerophosphodiester phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate." [EC:3.1.4.46] subset: gosubset_prok synonym: "gene hpd protein" RELATED [EC:3.1.4.46] synonym: "glycerophosphodiester glycerophosphohydrolase activity" EXACT [EC:3.1.4.46] synonym: "glycerophosphoryl diester phosphodiesterase activity" EXACT [EC:3.1.4.46] synonym: "IgD-binding protein D" RELATED [EC:3.1.4.46] xref: EC:3.1.4.46 xref: GO:0008889 xref: MetaCyc:GLYCPDIESTER-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0002228 name: glycine C-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate." [EC:2.3.1.29] subset: gosubset_prok synonym: "2-amino-3-ketobutyrate CoA ligase activity" EXACT [EC:2.3.1.29] synonym: "2-amino-3-ketobutyrate coenzyme A ligase activity" EXACT [EC:2.3.1.29] synonym: "2-amino-3-ketobutyrate-CoA ligase activity" EXACT [EC:2.3.1.29] synonym: "acetyl-CoA:glycine C-acetyltransferase activity" EXACT [EC:2.3.1.29] synonym: "aminoacetone synthase activity" EXACT [EC:2.3.1.29] synonym: "glycine acetyltransferase activity" EXACT [EC:2.3.1.29] xref: EC:2.3.1.29 xref: GO:0008890 xref: MetaCyc:AKBLIG-RXN is_a: CCO:F0003163 ! C-acetyltransferase activity [Term] id: CCO:F0002229 name: glycolate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: glycolate + O2 = glyoxylate + H2O2." [EC:1.1.3.15] subset: gosubset_prok xref: GO:0008891 xref: MetaCyc:RXN-969 is_a: CCO:F0008250 ! (S)-2-hydroxy-acid oxidase activity [Term] id: CCO:F0002230 name: guanine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: guanine + H2O = xanthine + NH3." [EC:3.5.4.3] subset: gosubset_prok synonym: "GAH activity" EXACT [EC:3.5.4.3] synonym: "guanase activity" EXACT [EC:3.5.4.3] synonym: "guanine aminase activity" EXACT [EC:3.5.4.3] synonym: "guanine aminohydrolase activity" EXACT [EC:3.5.4.3] xref: EC:3.5.4.3 xref: GO:0008892 xref: MetaCyc:GUANINE-DEAMINASE-RXN xref: Reactome:26482 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0002231 name: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate." [EC:3.1.7.2] subset: gosubset_prok synonym: "(ppGpp)ase activity" EXACT [EC:3.1.7.2] synonym: "guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase activity" EXACT [] synonym: "guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase activity" EXACT [EC:3.1.7.2] synonym: "guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase activity" EXACT [] synonym: "penta-phosphate guanosine-3'-diphosphohydrolase activity" EXACT [EC:3.1.7.2] synonym: "penta-phosphate guanosine-3'-pyrophosphohydrolase activity" EXACT [EC:3.1.7.2] synonym: "PpGpp phosphohydrolase activity" EXACT [EC:3.1.7.2] synonym: "PpGpp-3'-pyrophosphohydrolase activity" EXACT [EC:3.1.7.2] xref: EC:3.1.7.2 xref: GO:0008893 xref: MetaCyc:PPGPPSYN-RXN is_a: CCO:F0003364 ! diphosphoric monoester hydrolase activity [Term] id: CCO:F0002232 name: guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate." [EC:3.6.1.40] subset: gosubset_prok synonym: "guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase activity" EXACT [EC:3.6.1.40] synonym: "guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase activity" EXACT [EC:3.6.1.40] synonym: "guanosine pentaphosphatase activity" EXACT [EC:3.6.1.40] synonym: "guanosine pentaphosphate phosphatase activity" EXACT [EC:3.6.1.40] synonym: "guanosine pentaphosphate phosphohydrolase activity" EXACT [EC:3.6.1.40] synonym: "guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase activity" EXACT [EC:3.6.1.40] synonym: "guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase activity" EXACT [] synonym: "pppGpp 5'-phosphohydrolase activity" EXACT [EC:3.6.1.40] xref: EC:3.6.1.40 xref: GO:0008894 xref: MetaCyc:PPPGPPHYDRO-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0002233 name: heme lyase disulfide oxidoreductase activity namespace: molecular_function synonym: "haem lyase disulfide oxidoreductase activity" EXACT [] synonym: "heme lyase disulphide oxidoreductase activity" EXACT [] xref: GO:0008895 is_a: CCO:F0002532 ! protein disulfide oxidoreductase activity [Term] id: CCO:F0002235 name: homocysteine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine." [EC:2.1.1.10] subset: gosubset_prok synonym: "adenosylmethionine transmethylase activity" EXACT [EC:2.1.1.10] synonym: "adenosylmethionine:homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] synonym: "homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] synonym: "homocysteine transmethylase activity" EXACT [EC:2.1.1.10] synonym: "L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.10] synonym: "methylmethionine:homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] synonym: "S-adenosyl-L-methionine:L-homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] synonym: "S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.10] synonym: "S-adenosylmethionine homocysteine transmethylase activity" EXACT [EC:2.1.1.10] synonym: "S-adenosylmethionine-homocysteine transmethylase activity" EXACT [EC:2.1.1.10] synonym: "S-adenosylmethionine:homocysteine methyltransferase activity" EXACT [EC:2.1.1.10] synonym: "S-methylmethionine homocysteine transmethylase activity" EXACT [EC:2.1.1.10] xref: EC:2.1.1.10 xref: GO:0008898 xref: MetaCyc:HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN is_a: CCO:F0001759 ! S-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0002236 name: homoserine O-succinyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine." [EC:2.3.1.46] subset: gosubset_prok synonym: "homoserine O-transsuccinylase activity" BROAD [EC:2.3.1.46] synonym: "homoserine succinyltransferase activity" EXACT [EC:2.3.1.46] synonym: "succinyl-CoA:L-homoserine O-succinyltransferase activity" EXACT [EC:2.3.1.46] xref: EC:2.3.1.46 xref: GO:0008899 xref: MetaCyc:HOMSUCTRAN-RXN is_a: CCO:F0003325 ! O-succinyltransferase activity [Term] id: CCO:F0002237 name: hydrogen:potassium-exchanging ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in)." [EC:3.6.3.10] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "(K+ + H+)-ATPase activity" EXACT [EC:3.6.3.10] synonym: "ATP phosphohydrolase (H+/K+-exchanging)" EXACT [EC:3.6.3.10] synonym: "gastric H(+)/K(+) ATPase activity" NARROW [EC:3.6.3.10] synonym: "gastric H+/K+ ATPase" NARROW [EC:3.6.3.10] synonym: "H(+)/K(+)-ATPase activity" EXACT [EC:3.6.3.10] synonym: "H(+)/K(+)-exchanging ATPase activity" EXACT [EC:3.6.3.10] synonym: "H+-K+-ATPase activity" EXACT [EC:3.6.3.10] synonym: "H+/K+-ATPase activity" EXACT [EC:3.6.3.10] synonym: "H+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.10] synonym: "h+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.10] synonym: "H,K-ATPase activity" EXACT [EC:3.6.3.10] synonym: "hydrogen/potassium-exchanging ATPase activity" EXACT [] synonym: "hydrogen:potassium exchanging ATPase activity" EXACT [] synonym: "proton pump activity" BROAD [EC:3.6.3.10] xref: EC:3.6.3.10 xref: GO:0005390 xref: GO:0008900 xref: MetaCyc:3.6.3.10-RXN is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0002238 name: ferredoxin hydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2." [EC:1.12.7.2] comment: Note that this function was formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.98.1.1, EC 1.18.3.1 and EC 1.18.99.1. subset: gosubset_prok synonym: "[Fe] hydrogenase activity" EXACT [] synonym: "[Fe] hydrogenase gamma" RELATED [] synonym: "bidirectional hydrogenase activity" BROAD [EC:1.12.7.2] synonym: "H(2) oxidizing hydrogenase activity" BROAD [EC:1.12.7.2] synonym: "H(2) producing hydrogenase activity" BROAD [EC:1.12.7.2] synonym: "H2 oxidizing hydrogenase" BROAD [] synonym: "H2 producing hydrogenase" BROAD [] synonym: "hydrogen-lyase activity" BROAD [EC:1.12.7.2] synonym: "hydrogen:ferredoxin oxidoreductase activity" EXACT [] synonym: "hydrogenase (ferredoxin) activity" EXACT [EC:1.12.7.2] synonym: "hydrogenase activity" BROAD [] synonym: "hydrogenase I" RELATED [] synonym: "hydrogenase II" RELATED [] synonym: "hydrogenlyase activity" BROAD [EC:1.12.7.2] synonym: "iron hydrogenase activity" NARROW [] synonym: "iron-only hydrogenase activity" NARROW [] synonym: "Ni-Fe hydrogenase activity" NARROW [] synonym: "Ni-Fe-Se hydrogenase activity" NARROW [] synonym: "nickel hydrogenase activity" NARROW [] synonym: "nickel-iron hydrogenase activity" NARROW [] synonym: "nickel-iron-selenium hydrogenase activity" NARROW [] synonym: "uptake hydrogenase activity" BROAD [EC:1.12.7.2] xref: EC:1.12.7.2 xref: GO:0008901 xref: GO:0016948 xref: GO:0016949 xref: GO:0016950 xref: GO:0016951 xref: MetaCyc:HYDROG-RXN xref: UM-BBD_enzymeID:e0418 is_a: CCO:F0003284 ! oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor [Term] id: CCO:F0002239 name: hydroxymethylpyrimidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-amino-2-methyl-5-hydroxymethylpyrimidine = ADP + 4-amino-2-methyl-5-phosphomethylpyrimidine." [EC:2.7.1.49] subset: gosubset_prok synonym: "ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase activity" EXACT [EC:2.7.1.49] synonym: "hydroxymethylpyrimidine kinase (phosphorylating)" EXACT [EC:2.7.1.49] xref: EC:2.7.1.49 xref: GO:0008902 xref: MetaCyc:OHMETPYRKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002240 name: hydroxypyruvate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate." [EC:5.3.1.22] subset: gosubset_prok synonym: "hydroxypyruvate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.22] synonym: "hydroxypyruvate ketol-isomerase activity" EXACT [EC:5.3.1.22] xref: EC:5.3.1.22 xref: GO:0008903 xref: MetaCyc:RXN0-305 is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002241 name: aminoglycoside 7''-O-phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + aminoglycoside = ADP + 7''-O-phosphoaminoglycoside." [EC:2.7.1.119, GOC:cb, GOC:mah] subset: gosubset_prok synonym: "APH(7'') activity" EXACT [EC:2.7.1.119] synonym: "ATP:hygromycin-B 7''-O-phosphotransferase activity" NARROW [EC:2.7.1.119] synonym: "destomic acid ring 7''-O-phosphotransferase activity" EXACT [] synonym: "hygromycin B kinase activity" NARROW [] synonym: "hygromycin B phosphotransferase activity" NARROW [EC:2.7.1.119] synonym: "hygromycin-B kinase activity" NARROW [] xref: EC:2.7.1.119 xref: GO:0008904 xref: MetaCyc:HYGROMYCIN-B-KINASE-RXN is_a: CCO:F0005515 ! aminoglycoside phosphotransferase activity [Term] id: CCO:F0002242 name: mannose-phosphate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.7.7.- xref: GO:0008905 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002243 name: inosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + inosine = ADP + IMP." [EC:2.7.1.73] subset: gosubset_prok synonym: "ATP:inosine 5'-phosphotransferase activity" EXACT [EC:2.7.1.73] synonym: "inosine kinase (phosphorylating)" EXACT [EC:2.7.1.73] synonym: "inosine-guanosine kinase activity" RELATED [EC:2.7.1.73] xref: EC:2.7.1.73 xref: GO:0008906 xref: MetaCyc:INOSINEKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002244 name: integrase activity namespace: molecular_function def: "Catalysis of the integration of lambdoid phage DNA during establishment, probably by forming a transient DNA-protein link." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_goa subset: goslim_pir subset: gosubset_prok xref: GO:0008907 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0002245 name: isochorismatase activity namespace: molecular_function def: "Catalysis of the reaction: isochorismate + H2O = 2,3-dihydro-2,3-dihydroxybenzoate + pyruvate." [EC:3.3.2.1] subset: gosubset_prok synonym: "2,3 dihydro-2,3 dihydroxybenzoate synthase activity" EXACT [EC:3.3.2.1] synonym: "2,3-dihydro-2,3-dihydroxybenzoate synthase activity" EXACT [EC:3.3.2.1] synonym: "2,3-dihydroxy-2,3-dihydrobenzoate synthase activity" EXACT [EC:3.3.2.1] synonym: "2,3-dihydroxy-2,3-dihydrobenzoic synthase activity" EXACT [EC:3.3.2.1] synonym: "isochorismate pyruvate-hydrolase activity" EXACT [EC:3.3.2.1] xref: EC:3.3.2.1 xref: GO:0008908 xref: MetaCyc:ISOCHORMAT-RXN is_a: CCO:F0000863 ! leukotriene-A4 hydrolase activity [Term] id: CCO:F0002246 name: isochorismate synthase activity namespace: molecular_function def: "Catalysis of the reaction: chorismate = isochorismate." [EC:5.4.99.6] comment: Note that this function was formerly EC:5.4.99.6. subset: gosubset_prok synonym: "isochorismate hydroxymutase activity" EXACT [EC:5.4.4.2] synonym: "isochorismate mutase activity" EXACT [] synonym: "isochorismate synthetase activity" EXACT [EC:5.4.4.2] xref: EC:5.4.4.2 xref: GO:0008909 xref: MetaCyc:ISOCHORSYN-RXN is_a: CCO:F0007827 ! intramolecular transferase activity, transferring hydroxy groups [Term] id: CCO:F0002247 name: kanamycin kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + kanamycin = ADP + kanamycin 3'-phosphate." [EC:2.7.1.95] subset: gosubset_prok synonym: "aminoglycoside 3'-phosphotransferase activity" EXACT [EC:2.7.1.95] synonym: "APH(3') activity" EXACT [EC:2.7.1.95] synonym: "ATP:kanamycin 3'-O-phosphotransferase activity" EXACT [EC:2.7.1.95] synonym: "kanamycin kinase (phosphorylating)" EXACT [EC:2.7.1.95] synonym: "neomycin phosphotransferase activity" EXACT [EC:2.7.1.95] synonym: "neomycin-kanamycin phosphotransferase activity" EXACT [EC:2.7.1.95] xref: EC:2.7.1.95 xref: GO:0008910 xref: MetaCyc:KANAMYCIN-KINASE-RXN is_a: CCO:F0005515 ! aminoglycoside phosphotransferase activity [Term] id: CCO:F0002248 name: lactaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+." [EC:1.2.1.22] subset: gosubset_prok synonym: "(S)-lactaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.22] synonym: "L-lactaldehyde:NAD oxidoreductase activity" EXACT [EC:1.2.1.22] synonym: "nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase activity" EXACT [EC:1.2.1.22] xref: EC:1.2.1.22 xref: GO:0008911 xref: MetaCyc:LACTALDDEHYDROG-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002249 name: lactaldehyde reductase activity namespace: molecular_function def: "Catalysis of the reaction: (R) (or (S))-propane-1,2-diol + NAD+ = (R) (or (S))-lactaldehyde + NADH + H+." [EC:1.1.1.77] subset: gosubset_prok synonym: "(R)[or (S)]-propane-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.77] synonym: "L-lactaldehyde:propanediol oxidoreductase activity" EXACT [EC:1.1.1.77] synonym: "propanediol oxidoreductase activity" EXACT [EC:1.1.1.77] synonym: "propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity" EXACT [EC:1.1.1.77] xref: EC:1.1.1.77 xref: GO:0008912 xref: MetaCyc:LACTALDREDUCT-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002250 name: lauroyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "lauroyl transferase activity" EXACT [] xref: GO:0008913 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0002251 name: leucyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein." [EC:2.3.2.6] subset: gosubset_prok synonym: "L-leucyl-tRNA:protein leucyltransferase activity" EXACT [EC:2.3.2.6] synonym: "L/F transferase activity" EXACT [EC:2.3.2.6] synonym: "leucyl, phenylalanine-tRNA-protein transferase activity" EXACT [EC:2.3.2.6] synonym: "leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase activity" EXACT [EC:2.3.2.6] synonym: "leucyl-phenylalanine-transfer ribonucleate-protein transferase activity" EXACT [EC:2.3.2.6] synonym: "leucyl-tRNA--protein transferase activity" EXACT [EC:2.3.2.6] synonym: "leucyl/phenylalanyl-tRNA--protein transferase activity" EXACT [EC:2.3.2.6] xref: EC:2.3.2.6 xref: GO:0008914 xref: MetaCyc:LEUCYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0002252 name: lipid-A-disaccharide synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate." [EC:2.4.1.182] subset: gosubset_prok synonym: "UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-beta-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase activity" EXACT [EC:2.4.1.182] xref: EC:2.4.1.182 xref: GO:0008915 xref: MetaCyc:LIPIDADISACCHARIDESYNTH-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0002253 name: lipopolysaccharide N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide." [EC:2.4.1.56] subset: gosubset_prok synonym: "LPS N-acetylglucosaminyltransferase activity" EXACT [] synonym: "UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.56] synonym: "UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.56] synonym: "uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.56] xref: EC:2.4.1.56 xref: GO:0008917 xref: MetaCyc:2.4.1.56-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0002254 name: lipopolysaccharide 3-alpha-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide." [EC:2.4.1.44] subset: gosubset_prok synonym: "lipopolysaccharide 1,3-galactosyltransferase activity" EXACT [EC:2.4.1.44] synonym: "lipopolysaccharide galactosyltransferase activity" EXACT [] synonym: "lipopolysaccharide-alpha-1,3-D-galactosyltransferase" NARROW [] synonym: "LPS 3-alpha-galactosyltransferase activity" EXACT [] synonym: "UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.44] synonym: "UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase activity" EXACT [EC:2.4.1.44] synonym: "UDP-galactose:polysaccharide galactosyltransferase activity" EXACT [EC:2.4.1.44] synonym: "UDPgalactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.44] synonym: "uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase activity" EXACT [EC:2.4.1.44] synonym: "uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase activity" EXACT [EC:2.4.1.44] xref: EC:2.4.1.44 xref: GO:0008918 xref: MetaCyc:2.4.1.44-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0002255 name: lipopolysaccharide glucosyltransferase I activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide." [EC:2.4.1.58] subset: gosubset_prok synonym: "lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] synonym: "LPS glucosyltransferase I activity" EXACT [] synonym: "UDP-glucose:lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] synonym: "UDPglucose:lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] synonym: "UDPglucose:lipopolysaccharide glucosyltransferase I" RELATED [EC:2.4.1.58] synonym: "uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I" RELATED [EC:2.4.1.58] synonym: "uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.58] xref: EC:2.4.1.58 xref: GO:0008919 xref: MetaCyc:2.4.1.58-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0002256 name: lipopolysaccharide heptosyltransferase activity namespace: molecular_function subset: gosubset_prok synonym: "LPS heptosyltransferase activity" EXACT [] xref: GO:0008920 is_a: CCO:F0003332 ! transferase activity, transferring glycosyl groups [Term] id: CCO:F0002257 name: lipopolysaccharide-1,6-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide." [GOC:ai] synonym: "LPS-1,6-galactosyltransferase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0008921 is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0002258 name: long-chain-fatty-acid-[acyl-carrier-protein] ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]." [EC:6.2.1.20] subset: gosubset_prok synonym: "acyl-[acyl-carrier-protein] synthetase activity" EXACT [EC:6.2.1.20] synonym: "acyl-ACP synthetase activity" EXACT [] synonym: "acyl-acyl carrier protein synthetase" BROAD [EC:6.2.1.20] synonym: "acyl-acyl-carrier-protein synthetase activity" EXACT [EC:6.2.1.20] synonym: "acyl-acyl-carrier-proteinsynthetase activity" EXACT [EC:6.2.1.20] synonym: "long-chain fatty acid-[acyl-carrier-protein] ligase activity" EXACT [] synonym: "long-chain-fatty-acid-[acyl-carrier protein] ligase activity" EXACT [] synonym: "long-chain-fatty-acid-ACP ligase activity" EXACT [] synonym: "long-chain-fatty-acid-acyl-carrier-protein ligase activity" EXACT [EC:6.2.1.20] synonym: "long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity" EXACT [EC:6.2.1.20] synonym: "stearoyl-ACP synthetase activity" EXACT [EC:6.2.1.20] xref: EC:6.2.1.20 xref: GO:0008922 xref: GO:0010300 xref: MetaCyc:ACYLACPSYNTH-RXN is_a: CCO:F0002996 ! fatty-acid ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0002259 name: lysine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine = cadaverine + CO2." [EC:4.1.1.18] subset: gosubset_prok synonym: "L-lysine carboxy-lyase (cadaverine-forming)" EXACT [EC:4.1.1.18] synonym: "L-lysine carboxy-lyase activity" EXACT [EC:4.1.1.18] xref: EC:4.1.1.18 xref: GO:0008923 xref: MetaCyc:LYSDECARBOX-RXN xref: MetaCyc:PWY0-461 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002260 name: malate dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate + acceptor = oxaloacetate + reduced acceptor." [EC:1.1.99.16] subset: gosubset_prok synonym: "(S)-malate:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.16] synonym: "(S)-malate:acceptor oxidoreductase activity" EXACT [EC:1.1.99.16] synonym: "FAD-dependent malate-vitamin K reductase activity" EXACT [] synonym: "malate-vitamin K reductase activity" EXACT [] xref: EC:1.1.99.16 xref: GO:0008924 xref: MetaCyc:MALATE-DEHYDROGENASE-(ACCEPTOR)-RXN is_a: CCO:F0003217 ! malate dehydrogenase activity [Term] id: CCO:F0002261 name: maltose O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose." [EC:2.3.1.79] subset: gosubset_prok synonym: "acetyl-CoA:maltose O-acetyltransferase activity" EXACT [EC:2.3.1.79] synonym: "maltose transacetylase activity" EXACT [EC:2.3.1.79] xref: EC:2.3.1.79 xref: GO:0008925 xref: MetaCyc:MALTACETYLTRAN-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0002262 name: mannitol-1-phosphate 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+." [EC:1.1.1.17] subset: gosubset_prok xref: EC:1.1.1.17 xref: GO:0008926 xref: MetaCyc:MANNPDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002263 name: mannonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O." [EC:4.2.1.8] subset: gosubset_prok synonym: "altronate hydrolase activity" EXACT [EC:4.2.1.8] synonym: "altronic hydro-lyase activity" EXACT [EC:4.2.1.8] synonym: "D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)" EXACT [EC:4.2.1.8] synonym: "D-mannonate hydro-lyase activity" EXACT [EC:4.2.1.8] synonym: "D-mannonate hydrolyase activity" EXACT [EC:4.2.1.8] synonym: "mannonate hydrolyase activity" EXACT [EC:4.2.1.8] synonym: "mannonic hydrolase activity" EXACT [EC:4.2.1.8] xref: EC:4.2.1.8 xref: GO:0008927 xref: MetaCyc:MANNONDEHYDRAT-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002264 name: mannose-1-phosphate guanylyltransferase (GDP) activity namespace: molecular_function def: "Catalysis of the reaction: GDP + D-mannose 1-phosphate = phosphate + GDP-mannose." [EC:2.7.7.22] subset: gosubset_prok synonym: "GDP mannose phosphorylase activity" EXACT [EC:2.7.7.22] synonym: "GDP-mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] synonym: "GDP-mannose phosphorylase activity" EXACT [EC:2.7.7.22] synonym: "GDP-mannose pyrophosphorylase activity" RELATED [EC:2.7.7.22] synonym: "GDP:alpha-D-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] synonym: "GDP:D-mannose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] synonym: "GDP:mannose-1-phosphate guanylyltransferase activity" EXACT [] synonym: "guanosine diphosphate-mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] synonym: "guanosine diphosphomannose phosphorylase activity" EXACT [EC:2.7.7.22] synonym: "mannose 1-phosphate (guanosine diphosphate) guanylyltransferase activity" EXACT [EC:2.7.7.22] synonym: "mannose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.22] xref: EC:2.7.7.22 xref: GO:0008928 xref: MetaCyc:MANNPGUANYLTRANGDP-RXN is_a: CCO:F0002242 ! mannose-phosphate guanylyltransferase activity [Term] id: CCO:F0002265 name: methylglyoxal synthase activity namespace: molecular_function def: "Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate." [EC:4.2.3.3] subset: gosubset_prok synonym: "glycerone-phosphate phospho-lyase (methylglyoxal-forming)" EXACT [EC:4.2.3.3] synonym: "glycerone-phosphate phospho-lyase activity" EXACT [EC:4.2.3.3] synonym: "methylglyoxal synthetase activity" EXACT [EC:4.2.3.3] xref: EC:4.2.3.3 xref: GO:0008929 xref: MetaCyc:METHGLYSYN-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0002266 name: methylthioadenosine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose." [EC:3.2.2.16] subset: gosubset_prok synonym: "5'-methylthioadenosine nucleosidase activity" EXACT [EC:3.2.2.16] synonym: "MeSAdo nucleosidase activity" EXACT [EC:3.2.2.16] synonym: "methylthioadenosine methylthioribohydrolase activity" EXACT [EC:3.2.2.16] synonym: "MTA nucleosidase activity" EXACT [EC:3.2.2.16] synonym: "S-methyl-5'-thioadenosine adeninehyrolase activity" EXACT [EC:3.2.2.16] xref: EC:3.2.2.16 xref: GO:0008930 xref: MetaCyc:METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0002267 name: murein DD-endopeptidase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008931 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0002268 name: lytic endotransglycosylase activity namespace: molecular_function def: "Catalysis of the specific cleavage of the beta-1,4 glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends." [PMID:10964424, PMID:9642199] synonym: "murein lytic endotransglycosylase E activity" NARROW [] xref: EC:2.4.99.- xref: GO:0008932 is_a: CCO:F0002269 ! lytic transglycosylase activity [Term] id: CCO:F0002269 name: lytic transglycosylase activity namespace: molecular_function def: "Catalysis of the specific cleavage of the beta-1,4 glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues." [PMID:10964424] subset: gosubset_prok synonym: "murein transglycosylase B activity" NARROW [] synonym: "peptidoglycan lytic transglycosylase activity" EXACT [] xref: EC:3.2.1.- xref: GO:0008933 is_a: CCO:F0003332 ! transferase activity, transferring glycosyl groups [Term] id: CCO:F0002270 name: inositol-1(or 4)-monophosphatase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate." [EC:3.1.3.25] subset: gosubset_prok synonym: "inositol 1-phosphatase activity" EXACT [EC:3.1.3.25] synonym: "inositol monophosphate phosphatase activity" BROAD [EC:3.1.3.25] synonym: "inositol phosphatase activity" BROAD [EC:3.1.3.25] synonym: "inositol-phosphate phosphatase activity" EXACT [EC:3.1.3.25] synonym: "L-myo-inositol-1-phosphate phosphatase activity" EXACT [EC:3.1.3.25] synonym: "myo-inositol 1-phosphatase activity" EXACT [EC:3.1.3.25] synonym: "myo-inositol monophosphatase activity" BROAD [EC:3.1.3.25] synonym: "myo-inositol-1(or 4)-monophosphatase activity" EXACT [] synonym: "myo-inositol-1(or 4)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.25] synonym: "myo-inositol-1-phosphatase activity" EXACT [EC:3.1.3.25] synonym: "myo-inositol-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.25] xref: EC:3.1.3.25 xref: GO:0008934 xref: MetaCyc:MYO-INOSITOL-1(OR-4)-MONOPHOSPHATASE-RXN is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0002271 name: naphthoate synthase activity namespace: molecular_function def: "Catalysis of the reaction: O-succinylbenzoyl-CoA = 1,4-dihydroxy-2-naphthoate + CoA." [EC:4.1.3.36] subset: gosubset_prok synonym: "1,4-dihydroxy-2-naphthoate synthase activity" EXACT [EC:4.1.3.36] synonym: "DHNA synthetase activity" EXACT [EC:4.1.3.36] synonym: "dihydroxynaphthoate synthase activity" EXACT [EC:4.1.3.36] synonym: "dihydroxynaphthoic acid synthetase activity" EXACT [EC:4.1.3.36] synonym: "o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing) activity" EXACT [EC:4.1.3.36] synonym: "o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing; CoA-forming)" EXACT [EC:4.1.3.36] xref: EC:4.1.3.36 xref: GO:0008935 xref: MetaCyc:NAPHTHOATE-SYN-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0002272 name: nicotinamidase activity namespace: molecular_function def: "Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3." [EC:3.5.1.19] subset: gosubset_prok synonym: "NAMase activity" EXACT [EC:3.5.1.19] synonym: "namase activity" EXACT [EC:3.5.1.19] synonym: "nicotinamide amidase activity" EXACT [EC:3.5.1.19] synonym: "nicotinamide amidohydrolase activity" EXACT [EC:3.5.1.19] synonym: "nicotinamide deaminase activity" EXACT [EC:3.5.1.19] synonym: "nicotine deamidase activity" EXACT [EC:3.5.1.19] synonym: "YNDase activity" EXACT [EC:3.5.1.19] xref: EC:3.5.1.19 xref: GO:0008936 xref: MetaCyc:NICOTINAMID-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002273 name: ferredoxin reductase activity namespace: molecular_function def: "Catalysis of the reactions: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+." [EC:1.18.1.-] subset: gosubset_prok xref: EC:1.18.1.- xref: GO:0008937 is_a: CCO:F0003312 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor [Term] id: CCO:F0002274 name: nicotinate N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + nicotinate = S-adenosyl-L-homocysteine + N-methylnicotinate." [EC:2.1.1.7] synonym: "furanocoumarin 8-O-methyltransferase activity" EXACT [EC:2.1.1.7] synonym: "S-adenosyl-L-methionine:nicotinate N-methyltransferase activity" EXACT [EC:2.1.1.7] xref: EC:2.1.1.7 xref: GO:0008938 xref: MetaCyc:NICOTINATE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0002275 name: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: beta-nicotinate D-ribonucleotide + dimethylbenzimidazole = nicotinate + N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole." [EC:2.4.2.21] subset: gosubset_prok synonym: "CobT" RELATED [EC:2.4.2.21] synonym: "N(1)-alpha-phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] synonym: "N1-alpha-phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] synonym: "nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] synonym: "nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] synonym: "nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase activity" EXACT [EC:2.4.2.21] synonym: "nicotinate-nucleotide:5,6-dimethylbenzimidazole phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.21] synonym: "nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase activity" EXACT [EC:2.4.2.21] xref: EC:2.4.2.21 xref: GO:0008939 xref: MetaCyc:DMBPPRIBOSYLTRANS-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0002276 name: nitrate reductase activity namespace: molecular_function def: "Catalysis of the reaction: NO2- (nitrite) + acceptor = NO3- (nitrate) + reduced acceptor." [EC:1.7.99.4] subset: gosubset_prok synonym: "nitrate reductase (acceptor)" EXACT [EC:1.7.99.4] synonym: "nitrite:(acceptor) oxidoreductase" EXACT [EC:1.7.99.4] synonym: "nitrite:acceptor oxidoreductase" EXACT [EC:1.7.99.4] synonym: "respiratory nitrate reductase activity" NARROW [EC:1.7.99.4] xref: EC:1.7.99.4 xref: GO:0008940 xref: MetaCyc:NITRATREDUCT-RXN is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0002277 name: nitric oxide dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 NO3- + NADP+." [EC:1.14.12.17] subset: gosubset_prok synonym: "nitric oxide,NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.14.12.17] synonym: "NOD activity" EXACT [EC:1.14.12.17] xref: EC:1.14.12.17 xref: GO:0008941 xref: MetaCyc:1.14.12.17-RXN is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0002278 name: nitrite reductase [NAD(P)H] activity namespace: molecular_function def: "Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = NO2(-) (nitrite) + 3 NAD(P)H + 3 H+." [EC:1.7.1.4] comment: Note that this function was formerly EC:1.6.6.4. subset: gosubset_prok synonym: "ammonium-hydroxide:NAD(P)+ oxidoreductase activity" EXACT [EC:1.7.1.4] synonym: "assimilatory nitrite reductase activity" RELATED [EC:1.7.1.4] synonym: "NAD(P)H2:nitrite oxidoreductase activity" EXACT [EC:1.7.1.4] synonym: "NAD(P)H:nitrite oxidoreductase activity" EXACT [EC:1.7.1.4] synonym: "NADH-nitrite oxidoreductase activity" EXACT [EC:1.7.1.4] synonym: "NADPH-nitrite reductase activity" EXACT [EC:1.7.1.4] synonym: "nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity" EXACT [EC:1.7.1.4] synonym: "nitrite reductase [NAD(P)H2]" RELATED [EC:1.7.1.4] xref: EC:1.7.1.4 xref: GO:0008942 xref: MetaCyc:NITRITREDUCT-RXN is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0002279 name: glyceraldehyde-3-phosphate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: glyceraldehyde 3-phosphate + (phosphate / H2O) + NAD(P)+ = (3-phospho-D-glyceroyl-phosphate / 3-phospho-D-glycerate) + NAD(P)H + H+." [EC:1.2.1.12, EC:1.2.1.13, EC:1.2.1.9] comment: Note that the reaction with phosphate as a substrate produces 3-phospho-D-glyceroyl-phosphate. subset: gosubset_prok xref: EC:1.2.1.- xref: GO:0008943 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002280 name: oligopeptidase A activity namespace: molecular_function def: "Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5." [EC:3.4.24.70] subset: gosubset_prok synonym: "68000-M signalpeptide hydrolase activity" EXACT [EC:3.4.24.70] xref: EC:3.4.24.70 xref: GO:0008944 xref: MetaCyc:3.4.24.70-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0002281 name: oligopeptidase B activity namespace: molecular_function def: "Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline." [EC:3.4.21.83] subset: gosubset_prok synonym: "Escherichia coli alkaline proteinase II" RELATED [EC:3.4.21.83] synonym: "protease II activity" EXACT [EC:3.4.21.83] xref: EC:3.4.21.83 xref: GO:0008945 xref: MetaCyc:3.4.21.83-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0002282 name: oligonucleotidase activity namespace: molecular_function def: "Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates." [EC:3.1.13.3] comment: Note that enzymes with this activity usually also hydrolyze NAD+ to NMN and AMP. subset: gosubset_prok xref: EC:3.1.13.3 xref: GO:0008946 xref: MetaCyc:3.1.13.3-RXN is_a: CCO:F0000915 ! nuclease activity [Term] id: CCO:F0002283 name: omptin activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys." [EC:3.4.21.87] subset: gosubset_prok xref: EC:3.4.21.87 xref: GO:0008947 xref: MetaCyc:3.4.21.87-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0002284 name: oxaloacetate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: oxaloacetate = pyruvate + CO2." [EC:4.1.1.3] subset: gosubset_prok synonym: "oxalacetic acid decarboxylase activity" EXACT [EC:4.1.1.3] synonym: "oxalate beta-decarboxylase activity" EXACT [EC:4.1.1.3] synonym: "oxaloacetate beta-decarboxylase activity" EXACT [EC:4.1.1.3] synonym: "oxaloacetate carboxy-lyase (pyruvate-forming)" EXACT [EC:4.1.1.3] synonym: "oxaloacetate carboxy-lyase activity" EXACT [EC:4.1.1.3] xref: EC:4.1.1.3 xref: GO:0008948 xref: MetaCyc:OXALODECARB-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002285 name: oxalyl-CoA decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: oxalyl-CoA = formyl-CoA + CO2." [EC:4.1.1.8] subset: gosubset_prok synonym: "oxalyl coenzyme A decarboxylase activity" EXACT [EC:4.1.1.8] synonym: "oxalyl-CoA carboxy-lyase (formyl-CoA-forming)" EXACT [EC:4.1.1.8] synonym: "oxalyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.8] xref: EC:4.1.1.8 xref: GO:0008949 xref: MetaCyc:OXALYL-COA-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002286 name: palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity namespace: molecular_function synonym: "palmitoleoyl ACP-dependent acyltransferase activity" EXACT [] xref: EC:2.3.1.- xref: GO:0008951 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0002287 name: penicillin amidase activity namespace: molecular_function def: "Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate." [EC:3.5.1.11] subset: gosubset_prok synonym: "alpha-acylamino-beta-lactam acylhydrolase activity" EXACT [EC:3.5.1.11] synonym: "ampicillin acylase activity" EXACT [EC:3.5.1.11] synonym: "benzylpenicillin acylase activity" EXACT [EC:3.5.1.11] synonym: "novozym 217" RELATED [EC:3.5.1.11] synonym: "palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity" EXACT [] synonym: "penicillin acylase activity" EXACT [EC:3.5.1.11] synonym: "penicillin amidohydrolase activity" EXACT [EC:3.5.1.11] synonym: "semacylase activity" EXACT [EC:3.5.1.11] xref: EC:3.5.1.11 xref: GO:0008953 xref: MetaCyc:PENICILLIN-AMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002288 name: peptidoglycan synthetase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008954 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0002289 name: peptidoglycan glycosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate." [EC:2.4.1.129] subset: gosubset_prok synonym: "bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.129] synonym: "penicillin binding protein (3 or 1B) activity" NARROW [EC:2.4.1.129] synonym: "peptidoglycan TGase activity" EXACT [EC:2.4.1.129] synonym: "peptidoglycan transglycosylase activity" EXACT [EC:2.4.1.129] synonym: "PG-II activity" EXACT [EC:2.4.1.129] synonym: "undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity" EXACT [EC:2.4.1.129] xref: EC:2.4.1.129 xref: GO:0008955 xref: MetaCyc:PEPTIDOGLYCAN-GLYCOSYLTRANSFERASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0002290 name: peptidyl-dipeptidase Dcp activity namespace: molecular_function def: "Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly." [EC:3.4.15.5] subset: gosubset_prok synonym: "dipeptidyl carboxypeptidase (Dcp)" EXACT [EC:3.4.15.5] synonym: "dipeptidyl carboxypeptidase activity" EXACT [EC:3.4.15.5] xref: EC:3.4.15.5 xref: GO:0008956 xref: MetaCyc:3.4.15.5-RXN is_a: CCO:F0001785 ! metalloexopeptidase activity is_a: CCO:F0001791 ! peptidyl-dipeptidase activity [Term] id: CCO:F0002291 name: phenylacetaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+." [EC:1.2.1.39] subset: gosubset_prok synonym: "phenylacetaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.39] xref: EC:1.2.1.39 xref: GO:0008957 xref: MetaCyc:PHENDEHYD-RXN xref: UM-BBD_enzymeID:e0119 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002292 name: phosphate acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate." [EC:2.3.1.8] subset: gosubset_prok synonym: "acetyl-CoA:phosphate acetyltransferase activity" EXACT [EC:2.3.1.8] synonym: "phosphoacylase activity" EXACT [EC:2.3.1.8] synonym: "phosphotransacetylase activity" EXACT [EC:2.3.1.8] synonym: "PTA" RELATED [EC:2.3.1.8] xref: EC:2.3.1.8 xref: GO:0008959 xref: MetaCyc:PHOSACETYLTRANS-RXN is_a: CCO:F0003130 ! acetyltransferase activity [Term] id: CCO:F0002293 name: phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose." [EC:2.7.8.20] subset: gosubset_prok synonym: "oligosaccharide glycerophosphotransferase activity" EXACT [EC:2.7.8.20] synonym: "phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity" EXACT [EC:2.7.8.20] synonym: "phosphoglycerol transferase activity" RELATED [EC:2.7.8.20] synonym: "phosphoglycerol transferase I" RELATED [EC:2.7.8.20] xref: EC:2.7.8.20 xref: GO:0008960 xref: MetaCyc:PGLYCEROLTRANSI-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0002294 name: phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008961 is_a: CCO:F0003332 ! transferase activity, transferring glycosyl groups [Term] id: CCO:F0002295 name: phosphatidylglycerophosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate." [EC:3.1.3.27] subset: gosubset_prok synonym: "PGP phosphatase activity" EXACT [EC:3.1.3.27] synonym: "phosphatidylglycerol phosphatase activity" EXACT [EC:3.1.3.27] synonym: "phosphatidylglycerol phosphate phosphatase activity" EXACT [EC:3.1.3.27] synonym: "phosphatidylglycerophosphate phosphohydrolase activity" EXACT [EC:3.1.3.27] xref: EC:3.1.3.27 xref: GO:0008962 xref: MetaCyc:PGPPHOSPHA-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0002296 name: phospho-N-acetylmuramoyl-pentapeptide-transferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol." [EC:2.7.8.13] subset: gosubset_prok synonym: "MraY transferase activity" NARROW [EC:2.7.8.13] synonym: "phospho-MurNAc-pentapeptide transferase activity" EXACT [EC:2.7.8.13] synonym: "phospho-N-acetylmuramoyl pentapeptide translocase activity" EXACT [EC:2.7.8.13] synonym: "phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity" EXACT [EC:2.7.8.13] synonym: "phosphoacetylmuramoylpentapeptide translocase activity" EXACT [EC:2.7.8.13] synonym: "phosphoacetylmuramoylpentapeptidetransferase activity" EXACT [EC:2.7.8.13] synonym: "UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity" EXACT [EC:2.7.8.13] synonym: "UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity" EXACT [EC:2.7.8.13] synonym: "UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity" EXACT [EC:2.7.8.13] synonym: "UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity" EXACT [EC:2.7.8.13] synonym: "UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity" EXACT [EC:2.7.8.13] synonym: "UDP-MurNAc-pentapeptide phosphotransferase activity" EXACT [EC:2.7.8.13] xref: EC:2.7.8.13 xref: GO:0008963 xref: MetaCyc:PHOSNACMURPENTATRANSLYS-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0002297 name: phosphoenolpyruvate carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: phosphate + oxaloacetate = H2O + phosphoenolpyruvate + CO2." [EC:4.1.1.31] subset: gosubset_prok synonym: "PEP carboxylase activity" EXACT [EC:4.1.1.31] synonym: "PEPC" RELATED [EC:4.1.1.31] synonym: "PEPCase activity" EXACT [EC:4.1.1.31] synonym: "phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.31] synonym: "phosphate:oxaloacetate carboxy-lyase (phosphorylating)" EXACT [EC:4.1.1.31] synonym: "phosphoenolpyruvic carboxylase activity" EXACT [EC:4.1.1.31] synonym: "phosphopyruvate (phosphate) carboxylase activity" EXACT [EC:4.1.1.31] xref: EC:4.1.1.31 xref: GO:0008964 xref: MetaCyc:PEPCARBOX-RXN is_a: CCO:F0000990 ! phosphoenolpyruvate carboxykinase activity [Term] id: CCO:F0002298 name: phosphoenolpyruvate-protein phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine." [EC:2.7.3.9] subset: gosubset_prok synonym: "enzyme I of the phosphotransferase system" NARROW [EC:2.7.3.9] synonym: "phosphoenolpyruvate sugar phosphotransferase enzyme I activity" EXACT [EC:2.7.3.9] synonym: "phosphoenolpyruvate--protein phosphatase activity" EXACT [EC:2.7.3.9] synonym: "phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase activity" EXACT [EC:2.7.3.9] synonym: "phosphoenolpyruvate:protein-L-histidine Npi-phosphotransferase activity" EXACT [EC:2.7.3.9] synonym: "phosphopyruvate--protein factor phosphotransferase activity" EXACT [EC:2.7.3.9] synonym: "phosphopyruvate--protein phosphotransferase activity" EXACT [EC:2.7.3.9] synonym: "sugar--PEP phosphotransferase enzyme I activity" NARROW [EC:2.7.3.9] xref: EC:2.7.3.9 xref: GO:0008965 xref: MetaCyc:2.7.3.9-RXN is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0002299 name: phosphoglucosamine mutase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucosamine 1-phosphate = D-glucosamine 6-phosphate." [EC:5.4.2.10] subset: gosubset_prok synonym: "alpha-D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.10] synonym: "D-glucosamine 1,6-phosphomutase activity" EXACT [EC:5.4.2.10] xref: EC:5.4.2.10 xref: GO:0008966 xref: MetaCyc:5.4.2.10-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0002300 name: phosphoglycolate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phosphoglycolate + H2O = glycolate + phosphate." [EC:3.1.3.18] subset: gosubset_prok synonym: "2-phosphoglycolate phosphatase activity" EXACT [EC:3.1.3.18] synonym: "2-phosphoglycolate phosphohydrolase activity" EXACT [EC:3.1.3.18] synonym: "P-glycolate phosphatase activity" EXACT [EC:3.1.3.18] synonym: "phosphoglycolate hydrolase activity" EXACT [EC:3.1.3.18] synonym: "phosphoglycollate phosphatase activity" EXACT [EC:3.1.3.18] xref: EC:3.1.3.18 xref: GO:0008967 xref: MetaCyc:GPH-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0002301 name: D-sedoheptulose 7-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate." [MetaCyc:RXN0-4301, PMID:11279237, PMID:8631969] subset: gosubset_prok synonym: "phosphoheptose isomerase activity" EXACT [] xref: GO:0008968 xref: MetaCyc:RXN0-4301 is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0002302 name: phosphohistidine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphohistidine + H2O = histidine + phosphate." [GOC:mah] subset: gosubset_prok xref: EC:3.1.3.- xref: GO:0008969 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0002303 name: phospholipase A1 activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate." [EC:3.1.1.32] subset: gosubset_prok synonym: "phosphatidylcholine 1-acylhydrolase activity" EXACT [EC:3.1.1.32] xref: EC:3.1.1.32 xref: GO:0008970 xref: MetaCyc:PHOSPHOLIPASE-A1-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0000999 ! phospholipase activity [Term] id: CCO:F0002304 name: phosphomethylpyrimidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine." [EC:2.7.4.7] subset: gosubset_prok synonym: "ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase activity" EXACT [EC:2.7.4.7] synonym: "hydroxymethylpyrimidine phosphokinase activity" EXACT [EC:2.7.4.7] xref: EC:2.7.4.7 xref: GO:0008972 xref: MetaCyc:PYRIMSYN3-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0002305 name: phosphopentomutase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate." [EC:5.4.2.7] subset: gosubset_prok synonym: "alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase activity" EXACT [EC:5.4.2.7] synonym: "alpha-D-ribose 1,5-phosphomutase activity" EXACT [EC:5.4.2.7] synonym: "D-ribose 1,5-phosphomutase activity" EXACT [EC:5.4.2.7] synonym: "deoxyribomutase activity" RELATED [EC:5.4.2.7] synonym: "deoxyribose phosphomutase activity" RELATED [EC:5.4.2.7] synonym: "phosphodeoxyribomutase activity" RELATED [EC:5.4.2.7] synonym: "phosphoribomutase activity" EXACT [EC:5.4.2.7] xref: EC:5.4.2.7 xref: GO:0008973 xref: MetaCyc:PPENTOMUT-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0002306 name: phosphoribulokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate." [EC:2.7.1.19] subset: gosubset_prok synonym: "5-phosphoribulose kinase activity" EXACT [EC:2.7.1.19] synonym: "ATP:D-ribulose-5-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.19] synonym: "phosphopentokinase activity" RELATED [EC:2.7.1.19] synonym: "phosphoribulokinase (phosphorylating)" EXACT [EC:2.7.1.19] synonym: "PKK" RELATED [EC:2.7.1.19] synonym: "PRK" RELATED [EC:2.7.1.19] synonym: "PRuK" RELATED [EC:2.7.1.19] synonym: "ribulose phosphate kinase activity" EXACT [EC:2.7.1.19] synonym: "ribulose-5-phosphate kinase activity" EXACT [EC:2.7.1.19] xref: EC:2.7.1.19 xref: GO:0008974 xref: MetaCyc:PHOSPHORIBULOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002307 name: pitrilysin activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon." [EC:3.4.24.55] subset: gosubset_prok synonym: "Escherichia coli metalloproteinase Pi" RELATED [EC:3.4.24.55] synonym: "Escherichia coli protease III" RELATED [EC:3.4.24.55] synonym: "protease III activity" EXACT [EC:3.4.24.55] synonym: "protease Pi activity" EXACT [EC:3.4.24.55] synonym: "proteinase Pi" RELATED [EC:3.4.24.55] synonym: "PTR" RELATED [EC:3.4.24.55] xref: EC:3.4.24.55 xref: GO:0008975 xref: MetaCyc:3.4.24.55-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0002308 name: polyphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1)." [EC:2.7.4.1] subset: gosubset_prok synonym: "ATP-polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.1] synonym: "ATP:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.1] synonym: "polyphosphoric acid kinase activity" EXACT [EC:2.7.4.1] xref: EC:2.7.4.1 xref: GO:0008976 xref: MetaCyc:POLYPHOSPHATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0002309 name: prephenate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH + H+." [EC:1.3.1.12] subset: gosubset_prok synonym: "chorismate mutase--prephenate dehydrogenase activity" EXACT [EC:1.3.1.12] synonym: "hydroxyphenylpyruvate synthase activity" BROAD [EC:1.3.1.12] synonym: "prephenate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.12] xref: EC:1.3.1.12 xref: GO:0008977 xref: MetaCyc:PREPHENATEDEHYDROG-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002310 name: prepilin peptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine." [EC:3.4.23.43] subset: gosubset_prok xref: EC:3.4.23.43 xref: GO:0008978 xref: MetaCyc:3.4.23.43-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0002311 name: prophage integrase activity namespace: molecular_function subset: gosubset_prok xref: GO:0008979 is_a: CCO:F0002244 ! integrase activity [Term] id: CCO:F0002312 name: propionate kinase activity namespace: molecular_function def: "Catalysis of the reactions: (1) ATP + propanoate = ADP + propanoyl phosphate (2) ATP + acetate = ADP + acetyl phosphate." [EC:2.7.2.15] subset: gosubset_prok synonym: "ATP:propanoate phosphotransferase activity" EXACT [] synonym: "PduW" RELATED [] synonym: "propanoate kinase activity" EXACT [] synonym: "propionate/acetate kinase activity" EXACT [] synonym: "TdcD" RELATED [] xref: EC:2.7.2.15 xref: GO:0008980 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0002313 name: protease IV activity namespace: molecular_function subset: gosubset_prok xref: GO:0008981 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0002314 name: protein-N(PI)-phosphohistidine-sugar phosphotransferase activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [EC:2.7.1.69, GOC:mtg_transport, http://www.ucs.mun.ca/~n55lrb/general_pts.html, ISBN:0815340729, TC:4.A.-.-.-] subset: gosubset_prok synonym: "enzyme II of the phosphotransferase system" NARROW [EC:2.7.1.69] synonym: "enzyme IIl4ac" RELATED [EC:2.7.1.69] synonym: "gene bglC RNA formation factors" RELATED [EC:2.7.1.69] synonym: "gene glC proteins" RELATED [EC:2.7.1.69] synonym: "group translocator activity" RELATED [EC:2.7.1.69] synonym: "PEP--sugar phosphotransferase enzyme II activity" NARROW [EC:2.7.1.69] synonym: "PEP-dependent phosphotransferase enzyme II" RELATED [EC:2.7.1.69] synonym: "phosphoenolpyruvate-sugar phosphotransferase enzyme II" RELATED [EC:2.7.1.69] synonym: "phosphohistidinoprotein-hexose phosphoribosyltransferase activity" EXACT [EC:2.7.1.69] synonym: "phosphohistidinoprotein-hexose phosphotransferase activity" EXACT [EC:2.7.1.69] synonym: "phosphoprotein factor-hexose phosophotransferase activity" EXACT [EC:2.7.1.69] synonym: "phosphotransfer-driven group translocator" EXACT [] synonym: "phosphotransferase, phosphohistidinoprotein-hexose activity" EXACT [EC:2.7.1.69] synonym: "protein, specific or class, gene bglC" RELATED [EC:2.7.1.69] synonym: "protein-Np-phosphohistidine-sugar phosphotransferase activity" EXACT [] synonym: "protein-Npi-phospho-L-histidine:sugar N-pros-phosphotransferase activity" EXACT [EC:2.7.1.69] synonym: "protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase activity" EXACT [EC:2.7.1.69] synonym: "protein-Npi-phosphohistidine-sugar phosphotransferase activity" EXACT [EC:2.7.1.69] synonym: "protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase activity" EXACT [EC:2.7.1.69] synonym: "PTS permease activity" EXACT [EC:2.7.1.69] synonym: "PTS transporter" RELATED [EC:2.7.1.69] synonym: "ribonucleic acid formation factor, gene glC" RELATED [EC:2.7.1.69] synonym: "sucrose phosphotransferase system II" RELATED [EC:2.7.1.69] xref: EC:2.7.1.69 xref: GO:0008982 xref: GO:0015455 xref: GO:0015456 xref: MetaCyc:2.7.1.69-RXN is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004251 ! active transmembrane transporter activity [Term] id: CCO:F0002315 name: protein-glutamate O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester." [EC:2.1.1.80, RESID:AA0072] subset: gosubset_prok synonym: "MCP methyltransferase I" RELATED [EC:2.1.1.80] synonym: "MCP methyltransferase II" RELATED [EC:2.1.1.80] synonym: "methyl-accepting chemotaxis protein methyltransferase II" RELATED [EC:2.1.1.80] synonym: "methyl-accepting chemotaxis protein O-methyltransferase activity" NARROW [EC:2.1.1.80] synonym: "protein carboxyl-methylase activity" EXACT [EC:2.1.1.80] synonym: "protein carboxyl-O-methyltransferase activity" EXACT [EC:2.1.1.80] synonym: "protein carboxylmethyltransferase II" RELATED [EC:2.1.1.80] synonym: "protein carboxymethylase activity" EXACT [EC:2.1.1.80] synonym: "protein carboxymethyltransferase activity" EXACT [EC:2.1.1.80] synonym: "protein methylase II" RELATED [EC:2.1.1.80] synonym: "protein O-methyltransferase activity" EXACT [EC:2.1.1.80] synonym: "protein(aspartate)methyltransferase activity" EXACT [EC:2.1.1.80] synonym: "protein(carboxyl)methyltransferase activity" EXACT [EC:2.1.1.80] synonym: "S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase activity" EXACT [EC:2.1.1.80] synonym: "S-adenosylmethionine-glutamyl methyltransferase activity" EXACT [EC:2.1.1.80] synonym: "S-adenosylmethionine:protein-carboxyl O-methyltransferase activity" EXACT [EC:2.1.1.80] xref: EC:2.1.1.80 xref: GO:0008983 xref: MetaCyc:CHER-RXN xref: RESID:AA0072 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0002316 name: protein-glutamate methylesterase activity namespace: molecular_function def: "Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol." [EC:3.1.1.61, RESID:AA0072] subset: gosubset_prok synonym: "CheB methylesterase activity" NARROW [EC:3.1.1.61] synonym: "chemotaxis-specific methylesterase activity" NARROW [EC:3.1.1.61] synonym: "methyl-accepting chemotaxis protein methyl-esterase activity" NARROW [EC:3.1.1.61] synonym: "methylesterase CheB activity" NARROW [EC:3.1.1.61] synonym: "protein-L-glutamate-5-O-methyl-ester acylhydrolase activity" EXACT [EC:3.1.1.61] synonym: "protein-L-glutamate-O5-methyl-ester acylhydrolase activity" EXACT [EC:3.1.1.61] xref: EC:3.1.1.61 xref: GO:0008984 xref: MetaCyc:MCPMETEST-RXN xref: RESID:AA0072 is_a: CCO:F0008164 ! protein methylesterase activity [Term] id: CCO:F0002317 name: pyruvate dehydrogenase (cytochrome) activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1." [EC:1.2.2.2] subset: gosubset_prok synonym: "pyruvate:ferricytochrome-b1 oxidoreductase activity" EXACT [EC:1.2.2.2] synonym: "pyruvate:ubiquinone-8-oxidoreductase activity" EXACT [EC:1.2.2.2] synonym: "pyruvic (cytochrome b1) dehydrogenase activity" EXACT [EC:1.2.2.2] xref: EC:1.2.2.2 xref: GO:0008985 xref: MetaCyc:PYRUVOXID-RXN is_a: CCO:F0001103 ! pyruvate dehydrogenase activity is_a: CCO:F0003224 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor [Term] id: CCO:F0002318 name: pyruvate, water dikinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pyruvate + H2O = AMP + phosphoenolpyruvate + phosphate." [EC:2.7.9.2] subset: gosubset_prok synonym: "ATP:pyruvate, water phosphotransferase activity" EXACT [EC:2.7.9.2] synonym: "PEP synthase activity" EXACT [] synonym: "PEP synthetase activity" EXACT [EC:2.7.9.2] synonym: "phoephoenolpyruvate synthetase activity" EXACT [EC:2.7.9.2] synonym: "phosphoenolpyruvate synthase activity" EXACT [EC:2.7.9.2] synonym: "phosphoenolpyruvic synthase activity" EXACT [EC:2.7.9.2] synonym: "phosphopyruvate synthetase activity" EXACT [EC:2.7.9.2] synonym: "pyruvate,water dikinase activity" EXACT [EC:2.7.9.2] synonym: "pyruvate-water dikinase (phosphorylating)" EXACT [EC:2.7.9.2] synonym: "water pyruvate dikinase activity" EXACT [] xref: EC:2.7.9.2 xref: GO:0008986 xref: MetaCyc:PEPSYNTH-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003353 ! phosphotransferase activity, paired acceptors [Term] id: CCO:F0002319 name: quinolinate synthetase A activity namespace: molecular_function def: "Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate." [GOC:jl, MetaCyc:QUINOLINATE-SYNTHA-RXN] subset: gosubset_prok xref: GO:0008987 xref: MetaCyc:QUINOLINATE-SYNTHA-RXN is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0002320 name: rRNA (adenine-N6-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine." [EC:2.1.1.48] subset: gosubset_prok synonym: "ErmC 23S rRNA methyltransferase" NARROW [EC:2.1.1.48] synonym: "gene ksgA methyltransferase" NARROW [EC:2.1.1.48] synonym: "ribonucleic acid-adenine (N(6)) methylase activity" EXACT [EC:2.1.1.48] synonym: "ribonucleic acid-adenine (N6) methylase activity" EXACT [EC:2.1.1.48] synonym: "ribosomal ribonucleate adenine 6-methyltransferase activity" EXACT [EC:2.1.1.48] synonym: "S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity" EXACT [EC:2.1.1.48] synonym: "S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity" EXACT [EC:2.1.1.48] xref: EC:2.1.1.48 xref: GO:0008988 xref: MetaCyc:RRNA-(ADENINE-N6-)-METHYLTRANSFERASE-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0003155 ! rRNA (adenine) methyltransferase activity [Term] id: CCO:F0002321 name: rRNA (guanine-N1-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine." [EC:2.1.1.51] subset: gosubset_prok synonym: "ribosomal ribonucleate guanine 1-methyltransferase activity" EXACT [EC:2.1.1.51] synonym: "S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity" EXACT [EC:2.1.1.51] synonym: "S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase activity" EXACT [EC:2.1.1.51] xref: EC:2.1.1.51 xref: GO:0008989 xref: MetaCyc:RRNA-(GUANINE-N1-)-METHYLTRANSFERASE-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0003157 ! rRNA (guanine) methyltransferase activity [Term] id: CCO:F0002322 name: rRNA (guanine-N2-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine." [EC:2.1.1.52] subset: gosubset_prok synonym: "ribosomal ribonucleate guanine-2-methyltransferase activity" EXACT [EC:2.1.1.52] synonym: "S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase activity" EXACT [EC:2.1.1.52] synonym: "S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase activity" EXACT [EC:2.1.1.52] xref: EC:2.1.1.52 xref: GO:0008990 xref: MetaCyc:RRNA-(GUANINE-N2-)-METHYLTRANSFERASE-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0003157 ! rRNA (guanine) methyltransferase activity [Term] id: CCO:F0002323 name: serine-type signal peptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism." [GOC:mah] xref: EC:3.4.21.- xref: GO:0008991 is_a: CCO:F0000698 ! serine-type endopeptidase activity is_a: CCO:F0002335 ! signal peptidase activity [Term] id: CCO:F0002324 name: repressor LexA activity namespace: molecular_function def: "Catalysis of the hydrolysis of Ala-Gly bond in repressor lexA." [EC:3.4.21.88] subset: gosubset_prok synonym: "LexA repressor" RELATED [EC:3.4.21.88] synonym: "repressor lexA" RELATED [EC:3.4.21.88] xref: EC:3.4.21.88 xref: GO:0008992 xref: MetaCyc:3.4.21.88-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0002325 name: rhamnulokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate." [EC:2.7.1.5] subset: gosubset_prok synonym: "ATP:L-rhamnulose 1-phosphotransferase activity" EXACT [EC:2.7.1.5] synonym: "L-rhamnulokinase activity" EXACT [EC:2.7.1.5] synonym: "L-rhamnulose kinase activity" EXACT [EC:2.7.1.5] synonym: "rhamnulokinase (phosphorylating)" EXACT [EC:2.7.1.5] synonym: "rhamnulose kinase activity" EXACT [EC:2.7.1.5] synonym: "RhuK" RELATED [EC:2.7.1.5] xref: EC:2.7.1.5 xref: GO:0008993 xref: MetaCyc:RHAMNULOKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002326 name: rhamnulose-1-phosphate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde." [EC:4.1.2.19] subset: gosubset_prok synonym: "L-rhamnulose 1-phosphate aldolase activity" EXACT [EC:4.1.2.19] synonym: "L-rhamnulose-1-phosphate lactaldehyde-lyase activity" EXACT [EC:4.1.2.19] synonym: "L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.19] synonym: "L-rhamnulose-phosphate aldolase activity" EXACT [EC:4.1.2.19] synonym: "rhamnulose phosphate aldolase activity" EXACT [EC:4.1.2.19] xref: EC:4.1.2.19 xref: GO:0008994 xref: MetaCyc:RHAMNULPALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0002327 name: ribonuclease E activity namespace: molecular_function def: "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group." [PMID:10722715, PMID:16854990] subset: gosubset_prok xref: GO:0008995 is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0002328 name: ribonuclease G activity namespace: molecular_function def: "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group." [PMID:10722715, PMID:16854990] subset: gosubset_prok xref: GO:0008996 is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0002329 name: ribonuclease R activity namespace: molecular_function def: "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides." [PMID:11948193] subset: gosubset_prok xref: EC:3.1.11.- xref: GO:0008997 is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0002330 name: ribonucleoside-triphosphate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin." [EC:1.17.4.2] subset: gosubset_prok synonym: "2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity" EXACT [EC:1.17.4.2] synonym: "2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity" EXACT [EC:1.17.4.2] synonym: "ribonucleotide reductase activity" BROAD [EC:1.17.4.2] xref: EC:1.17.4.2 xref: GO:0008998 xref: MetaCyc:1.17.4.2-RXN is_a: CCO:F0003310 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor [Term] id: CCO:F0002331 name: ribosomal-protein-alanine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine." [EC:2.3.1.128] subset: gosubset_prok synonym: "acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase activity" EXACT [EC:2.3.1.128] synonym: "ribosomal protein S18 acetyltransferase activity" EXACT [EC:2.3.1.128] xref: EC:2.3.1.128 xref: GO:0008999 xref: MetaCyc:2.3.1.128-RXN is_a: CCO:F0000978 ! peptide alpha-N-acetyltransferase activity [Term] id: CCO:F0002332 name: selenocysteine lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor." [EC:4.4.1.16] subset: gosubset_prok synonym: "L-selenocysteine selenide-lyase (L-alanine-forming)" EXACT [EC:4.4.1.16] synonym: "selenocysteine beta-lyase activity" EXACT [EC:4.4.1.16] synonym: "selenocysteine reductase activity" EXACT [EC:4.4.1.16] xref: EC:4.4.1.16 xref: GO:0009000 xref: MetaCyc:SELENOCYSTEINE-LYASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0002333 name: serine O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-serine = CoA + O-acetyl-L-serine." [EC:2.3.1.30] subset: gosubset_prok synonym: "acetyl-CoA:L-serine O-acetyltransferase activity" EXACT [EC:2.3.1.30] synonym: "L-serine acetyltransferase activity" EXACT [EC:2.3.1.30] synonym: "SATase activity" EXACT [EC:2.3.1.30] synonym: "serine acetyltransferase activity" EXACT [EC:2.3.1.30] synonym: "serine transacetylase activity" EXACT [EC:2.3.1.30] xref: EC:2.3.1.30 xref: GO:0009001 xref: MetaCyc:SERINE-O-ACETTRAN-RXN is_a: CCO:F0003135 ! serine O-acyltransferase activity is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0002334 name: serine-type D-Ala-D-Ala carboxypeptidase activity namespace: molecular_function def: "Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine." [EC:3.4.16.4] subset: gosubset_prok synonym: "D-alanine carboxypeptidase" BROAD [EC:3.4.16.4] synonym: "D-alanyl carboxypeptidase activity" EXACT [EC:3.4.16.4] synonym: "D-alanyl-D-alanine carboxypeptidase activity" EXACT [EC:3.4.16.4] synonym: "D-alanyl-D-alanine-carboxypeptidase activity" EXACT [EC:3.4.16.4] synonym: "D-alanyl-D-alanine-cleaving peptidase activity" EXACT [EC:3.4.16.4] synonym: "D-alanyl-D-alanine-cleaving-peptidase activity" EXACT [EC:3.4.16.4] synonym: "DD-carboxypeptidase" BROAD [EC:3.4.16.4] synonym: "DD-peptidase activity" EXACT [EC:3.4.16.4] synonym: "DD-transpeptidase activity" EXACT [EC:3.4.16.4] xref: EC:3.4.16.4 xref: GO:0009002 xref: MetaCyc:3.4.16.4-RXN is_a: CCO:F0000654 ! serine carboxypeptidase activity [Term] id: CCO:F0002335 name: signal peptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a signal peptide from a protein precursor." [GOC:mah] subset: gosubset_prok xref: GO:0009003 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0002336 name: signal peptidase I activity namespace: molecular_function def: "Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor." [EC:3.4.21.89] subset: gosubset_prok synonym: "bacterial leader peptidase 1" RELATED [EC:3.4.21.89] synonym: "bacterial leader peptidase I activity" NARROW [EC:3.4.21.89] synonym: "Escherichia coli leader peptidase" NARROW [EC:3.4.21.89] synonym: "eukaryotic signal peptidase" NARROW [EC:3.4.21.89] synonym: "eukaryotic signal proteinase" NARROW [EC:3.4.21.89] synonym: "HOSP" RELATED [EC:3.4.21.89] synonym: "leader peptidase activity" EXACT [EC:3.4.21.89] synonym: "leader peptidase I" RELATED [EC:3.4.21.89] synonym: "leader peptide hydrolase activity" EXACT [EC:3.4.21.89] synonym: "leader proteinase activity" EXACT [EC:3.4.21.89] synonym: "phage-procoat-leader peptidase activity" NARROW [EC:3.4.21.89] synonym: "pilin leader peptidase" NARROW [EC:3.4.21.89] synonym: "prokaryotic leader peptidase" NARROW [EC:3.4.21.89] synonym: "prokaryotic signal peptidase" NARROW [EC:3.4.21.89] synonym: "prokaryotic signal proteinase" NARROW [EC:3.4.21.89] synonym: "propeptidase activity" EXACT [EC:3.4.21.89] synonym: "PuIO prepilin peptidase" NARROW [EC:3.4.21.89] synonym: "signal peptide hydrolase activity" EXACT [EC:3.4.21.89] synonym: "signal proteinase activity" EXACT [EC:3.4.21.89] synonym: "signalase activity" EXACT [EC:3.4.21.89] synonym: "SPase I activity" EXACT [EC:3.4.21.89] synonym: "SPC" RELATED [EC:3.4.21.89] xref: EC:3.4.21.89 xref: GO:0009004 xref: MetaCyc:3.4.21.89-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity is_a: CCO:F0002335 ! signal peptidase activity [Term] id: CCO:F0002337 name: signal peptidase II activity namespace: molecular_function def: "Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group." [EC:3.4.23.36] subset: gosubset_prok synonym: "leader peptidase II" RELATED [EC:3.4.23.36] synonym: "lipoprotein signal peptidase activity" EXACT [EC:3.4.23.36] synonym: "premurein leader proteinase activity" EXACT [EC:3.4.23.36] synonym: "premurein-leader peptidase activity" NARROW [EC:3.4.23.36] synonym: "prolipoprotein signal peptidase activity" EXACT [EC:3.4.23.36] synonym: "prolipoprotein-signal peptidase activity" EXACT [EC:3.4.23.36] synonym: "SPase II activity" EXACT [EC:3.4.23.36] xref: EC:3.4.23.36 xref: GO:0009005 xref: MetaCyc:3.4.23.36-RXN is_a: CCO:F0002375 ! aspartic-type signal peptidase activity [Term] id: CCO:F0002338 name: site-specific DNA-methyltransferase (adenine-specific) activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine." [EC:2.1.1.72] subset: gosubset_prok synonym: "DNA adenine methylase" BROAD [] synonym: "EcoRI methylase" NARROW [EC:2.1.1.37, EC:2.1.1.72] synonym: "modification methylase activity" RELATED [EC:2.1.1.72] synonym: "N-6 adenine-specific DNA methylase activity" EXACT [EC:2.1.1.72] synonym: "restriction-modification system activity" RELATED [EC:2.1.1.72] xref: EC:2.1.1.72 xref: GO:0009007 xref: MetaCyc:2.1.1.72-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity is_a: CCO:F0002339 ! DNA-methyltransferase activity [Term] id: CCO:F0002339 name: DNA-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to a DNA molecule." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "deoxyribonucleate methylase activity" EXACT [EC:2.1.1.-] synonym: "deoxyribonucleate methyltransferase activity" EXACT [EC:2.1.1.-] synonym: "deoxyribonucleic acid methylase activity" EXACT [EC:2.1.1.-] synonym: "deoxyribonucleic acid methyltransferase activity" EXACT [EC:2.1.1.-] synonym: "deoxyribonucleic acid modification methylase activity" RELATED [EC:2.1.1.-] synonym: "DNA methylase" BROAD [] synonym: "DNA methyltransferase activity" EXACT [] synonym: "DNA transmethylase activity" EXACT [EC:2.1.1.-] synonym: "Type II DNA methylase" RELATED [EC:2.1.1.37] xref: EC:2.1.1.- xref: GO:0009008 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0002340 name: site-specific recombinase activity namespace: molecular_function def: "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences." [GOC:elh] comment: Consider also annotating to the molecular function term 'double-stranded DNA binding ; GO:0003690'. Note that this term is not a child of 'recombinase activity ; GO:0000150' because the latter represents activities that do not break or form phosphodiester bonds. subset: goslim_pir subset: gosubset_prok xref: GO:0009009 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0002341 name: sorbitol-6-phosphate 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+." [EC:1.1.1.140] subset: gosubset_prok synonym: "D-glucitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] synonym: "D-sorbitol 6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] synonym: "D-sorbitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] synonym: "D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.140] synonym: "glucitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.140] synonym: "ketosephosphate reductase activity" EXACT [EC:1.1.1.140] synonym: "sorbitol-6-P-dehydrogenase activity" EXACT [EC:1.1.1.140] xref: EC:1.1.1.140 xref: GO:0009010 xref: MetaCyc:SORB6PDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002342 name: starch synthase activity namespace: molecular_function def: "Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1)." [EC:2.4.1.21] subset: gosubset_prok synonym: "adenosine diphosphate glucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] synonym: "adenosine diphosphoglucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] synonym: "ADP-glucose starch synthase activity" EXACT [EC:2.4.1.21] synonym: "ADP-glucose transglucosylase activity" EXACT [EC:2.4.1.21] synonym: "ADP-glucose--starch glucosyltransferase activity" EXACT [EC:2.4.1.21] synonym: "ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.21] synonym: "ADPG starch synthetase activity" EXACT [EC:2.4.1.21] synonym: "ADPG-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] synonym: "ADPglucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.21] synonym: "ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.21] synonym: "glycogen synthase activity" EXACT [EC:2.4.1.21] synonym: "starch (bacterial glycogen) synthase activity" NARROW [EC:2.4.1.21] synonym: "starch synthetase activity" EXACT [EC:2.4.1.21] xref: EC:2.4.1.21 xref: GO:0009011 xref: MetaCyc:GLYCOGENSYN-RXN is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0002343 name: aminoglycoside 3''-adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + aminoglycoside = diphosphate + 3''-adenylylaminoglycoside." [EC:2.7.7.47, GOC:cb] subset: gosubset_prok synonym: "AAD (3'')" RELATED [EC:2.7.7.47] synonym: "ATP:streptomycin 3''-adenylyltransferase activity" NARROW [] synonym: "streptomycin 3''-adenylyltransferase activity" NARROW [] xref: EC:2.7.7.47 xref: GO:0009012 xref: MetaCyc:STREPTOMYCIN-3 is_a: CCO:F0005512 ! aminoglycoside nucleotidyltransferase activity [Term] id: CCO:F0002344 name: succinate-semialdehyde dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+." [EC:1.2.1.16] subset: gosubset_prok synonym: "succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate))" EXACT [EC:1.2.1.16] synonym: "succinate-semialdehyde:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.16] xref: EC:1.2.1.16 xref: GO:0009013 xref: MetaCyc:SUCCSEMIALDDEHYDROG-RXN xref: UM-BBD_enzymeID:e0020 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002345 name: succinyl-diaminopimelate desuccinylase activity namespace: molecular_function def: "Catalysis of the reaction: N-succinyl-LL-2,6-diaminoheptanedioate + H2O = succinate + LL-2,6-diaminoheptanedioate." [EC:3.5.1.18] subset: gosubset_prok synonym: "N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase activity" EXACT [EC:3.5.1.18] synonym: "N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase activity" EXACT [EC:3.5.1.18] xref: EC:3.5.1.18 xref: GO:0009014 xref: MetaCyc:SUCCDIAMINOPIMDESUCC-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002346 name: N-succinylarginine dihydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N2-succinyl-L-arginine + 2 H2O = N2-succinyl-L-ornithine + 2 NH3 + CO." [EC:3.5.3.23] subset: gosubset_prok synonym: "2-N-succinyl-L-arginine iminohydrolase (decarboxylating)" EXACT [EC:3.5.3.23] synonym: "arginine succinylhydrolase activity" EXACT [] synonym: "AruB" RELATED [] synonym: "AstB" RELATED [] synonym: "N2-succinyl-L-arginine iminohydrolase (decarboxylating)" EXACT [] synonym: "N2-succinylarginine dihydrolase activity" EXACT [] synonym: "SADH" RELATED [] synonym: "succinylarginine dihydrolase activity" EXACT [] xref: EC:3.5.3.23 xref: GO:0009015 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0002347 name: succinyldiaminopimelate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-L-2-amino-6-oxoheptanedioate + L-glutamate." [EC:2.6.1.17] subset: gosubset_prok synonym: "N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.17] synonym: "N-succinyl-L-diaminopimelic glutamic transaminase activity" EXACT [EC:2.6.1.17] synonym: "succinyldiaminopimelate aminotransferase activity" EXACT [] synonym: "succinyldiaminopimelate transferase activity" EXACT [EC:2.6.1.17] xref: EC:2.6.1.17 xref: GO:0009016 xref: MetaCyc:SUCCINYLDIAMINOPIMTRANS-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0002348 name: succinylglutamate desuccinylase activity namespace: molecular_function def: "Catalysis of the reaction: N-succinyl-L-glutamate + H2O = succinate + L-glutamate." [EC:3.5.1.96] subset: gosubset_prok synonym: "AstE" RELATED [] synonym: "N-succinyl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.96] synonym: "N2-succinylglutamate desuccinylase activity" EXACT [] synonym: "SGDS" RELATED [] xref: EC:3.5.1.96 xref: GO:0009017 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002349 name: sucrose phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate." [EC:2.4.1.7] subset: gosubset_prok synonym: "disaccharide glucosyltransferase activity" BROAD [EC:2.4.1.7] synonym: "sucrose glucosyltransferase activity" EXACT [EC:2.4.1.7] synonym: "sucrose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.7] xref: EC:2.4.1.7 xref: GO:0009018 xref: MetaCyc:SUCROSE-PHOSPHORYLASE-RXN is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0002350 name: tRNA (guanine-N1-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine." [EC:2.1.1.31] subset: gosubset_prok synonym: "S-adenosyl-L-methionine:tRNA (guanine-1-N-)-methyltransferase activity" EXACT [EC:2.1.1.31] synonym: "S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase activity" EXACT [EC:2.1.1.31] synonym: "transfer ribonucleate guanine 1-methyltransferase activity" EXACT [EC:2.1.1.31] synonym: "tRNA guanine 1-methyltransferase activity" EXACT [EC:2.1.1.31] xref: EC:2.1.1.31 xref: GO:0009019 xref: MetaCyc:TRNA-(GUANINE-N1-)-METHYLTRANSFERASE-RXN is_a: CCO:F0003146 ! tRNA (guanine) methyltransferase activity [Term] id: CCO:F0002351 name: tRNA (guanosine-2'-O-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine." [EC:2.1.1.34] subset: gosubset_prok synonym: "S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase activity" EXACT [EC:2.1.1.34] synonym: "S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] synonym: "transfer ribonucleate guanosine 2'-methyltransferase activity" EXACT [EC:2.1.1.34] synonym: "tRNA (Gm18) 2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] synonym: "tRNA (Gm18) methyltransferase activity" EXACT [EC:2.1.1.34] synonym: "tRNA (guanosine 2')-methyltransferase activity" EXACT [EC:2.1.1.34] synonym: "tRNA guanosine 2'-methyltransferase activity" EXACT [EC:2.1.1.34] synonym: "tRNA guanosine-2'-O-methyltransferase activity" EXACT [EC:2.1.1.34] xref: EC:2.1.1.34 xref: GO:0009020 xref: MetaCyc:2.1.1.34-RXN is_a: CCO:F0003146 ! tRNA (guanine) methyltransferase activity [Term] id: CCO:F0002352 name: tRNA (uracil-5-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine." [EC:2.1.1.35] subset: gosubset_prok synonym: "m5U-methyltransferase activity" EXACT [EC:2.1.1.35] synonym: "M5U-methyltransferase activity" EXACT [EC:2.1.1.35] synonym: "ribothymidyl synthase activity" BROAD [EC:2.1.1.35] synonym: "RUMT activity" EXACT [EC:2.1.1.35] synonym: "S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity" EXACT [EC:2.1.1.35] synonym: "transfer RNA uracil 5-methyltransferase activity" EXACT [EC:2.1.1.35] synonym: "transfer RNA uracil methylase activity" EXACT [EC:2.1.1.35] synonym: "tRNA uracil 5-methyltransferase activity" EXACT [EC:2.1.1.35] synonym: "tRNA:m(5)U54-methyltransferase activity" EXACT [EC:2.1.1.35] synonym: "tRNA:m5U54-methyltransferase activity" EXACT [EC:2.1.1.35] xref: EC:2.1.1.35 xref: GO:0009021 xref: MetaCyc:TRNA-(URACIL-5-)-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity is_a: CCO:F0003113 ! tRNA (uracil) methyltransferase activity [Term] id: CCO:F0002353 name: tRNA nucleotidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate." [EC:2.7.7.56] subset: gosubset_prok synonym: "phosphate-dependent exonuclease activity" RELATED [EC:2.7.7.56] synonym: "ribonuclease PH activity" EXACT [EC:2.7.7.56] synonym: "RNase PH activity" EXACT [EC:2.7.7.56] synonym: "tRNA:phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.56] xref: EC:2.7.7.56 xref: GO:0009022 xref: MetaCyc:TRNA-NUCLEOTIDYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002354 name: tagatose-6-phosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate." [EC:2.7.1.144] subset: gosubset_prok synonym: "ATP:D-tagatose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.144] synonym: "phosphotagatokinase activity" EXACT [EC:2.7.1.144] xref: EC:2.7.1.144 xref: GO:0009024 xref: MetaCyc:TAGAKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002355 name: tagatose-bisphosphate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate." [EC:4.1.2.40] subset: gosubset_prok synonym: "AgaY" RELATED [] synonym: "AgaZ" RELATED [] synonym: "D-tagatose-1,6-bisphosphate aldolase activity" EXACT [EC:4.1.2.40] synonym: "D-tagatose-1,6-bisphosphate D-glyceraldehyde 3-phosphate-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.40] synonym: "D-tagatose-1,6-bisphosphate triosephosphate lyase activity" EXACT [] synonym: "D-tagatose-1xxx,6-bisphosphate triosephosphate lyase activity" EXACT [EC:4.1.2.40] synonym: "KbaY" RELATED [] synonym: "tagatose 1,6-diphosphate aldolase activity" EXACT [EC:4.1.2.40] synonym: "tagatose-1,6-bisphosphate aldolase 1" EXACT [] xref: EC:4.1.2.40 xref: GO:0009025 xref: MetaCyc:TAGAALDOL-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0002356 name: tagaturonate reductase activity namespace: molecular_function def: "Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + NADH + H+." [EC:1.1.1.58] subset: gosubset_prok synonym: "altronate dehydrogenase activity" EXACT [EC:1.1.1.58] synonym: "altronate oxidoreductase activity" EXACT [EC:1.1.1.58] synonym: "altronic oxidoreductase activity" EXACT [EC:1.1.1.58] synonym: "D-altronate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.58] synonym: "D-tagaturonate reductase activity" EXACT [EC:1.1.1.58] synonym: "tagaturonate dehydrogenase activity" EXACT [EC:1.1.1.58] synonym: "TagUAR" RELATED [EC:1.1.1.58] xref: EC:1.1.1.58 xref: GO:0009026 xref: MetaCyc:ALTRO-OXIDOREDUCT-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002357 name: tartrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+." [EC:1.1.1.93] subset: gosubset_prok synonym: "mesotartrate dehydrogenase activity" EXACT [EC:1.1.1.93] synonym: "tartrate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.93] xref: EC:1.1.1.93 xref: GO:0009027 xref: MetaCyc:TARTRATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002358 name: tartronate-semialdehyde synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 glyoxylate = tartronate semialdehyde + CO2." [EC:4.1.1.47] subset: gosubset_prok synonym: "glyoxalate carboligase activity" EXACT [EC:4.1.1.47] synonym: "glyoxylate carbo-ligase activity" EXACT [EC:4.1.1.47] synonym: "glyoxylate carboligase activity" EXACT [EC:4.1.1.47] synonym: "glyoxylate carboxy-lyase (dimerizing)" EXACT [EC:4.1.1.47] synonym: "glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)" EXACT [EC:4.1.1.47] synonym: "glyoxylic carbo-ligase activity" EXACT [EC:4.1.1.47] synonym: "hydroxymalonic semialdehyde carboxylase activity" EXACT [EC:4.1.1.47] synonym: "tartronate semialdehyde carboxylase activity" EXACT [EC:4.1.1.47] synonym: "tartronic semialdehyde carboxylase activity" EXACT [EC:4.1.1.47] xref: EC:4.1.1.47 xref: GO:0009028 xref: MetaCyc:GLYOCARBOLIG-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002359 name: tetraacyldisaccharide 4'-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(beta-D-1,6)-2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl beta-phosphate = ADP + 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate." [EC:2.7.1.130] subset: gosubset_prok synonym: "ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4'-O-phosphotransferase activity" EXACT [EC:2.7.1.130] synonym: "lipid-A 4'-kinase activity" RELATED [EC:2.7.1.130] xref: EC:2.7.1.130 xref: GO:0009029 xref: MetaCyc:TETRAACYLDISACC4KIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002360 name: thiamin phosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + thiamin phosphate = ADP + thiamin diphosphate." [EC:2.7.4.16] subset: gosubset_prok synonym: "ATP:thiamine-phosphate phosphotransferase activity" EXACT [EC:2.7.4.16] synonym: "thiamin monophosphatase activity" EXACT [EC:2.7.4.16] synonym: "thiamin monophosphokinase activity" EXACT [EC:2.7.4.16] synonym: "thiamin-monophosphate kinase activity" EXACT [EC:2.7.4.16] synonym: "thiamin-phosphate kinase activity" EXACT [] synonym: "thiamine-monophosphate kinase activity" EXACT [EC:2.7.4.16] synonym: "thiamine-phosphate kinase activity" EXACT [] xref: EC:2.7.4.16 xref: GO:0009030 xref: MetaCyc:THI-P-KIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0002361 name: thymidine phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate." [EC:2.4.2.4] subset: gosubset_prok synonym: "animal growth regulators, blood platelet-derived endothelial cell growth factors" RELATED [EC:2.4.2.4] synonym: "blood platelet-derived endothelial cell growth factor" RELATED [EC:2.4.2.4] synonym: "deoxythymidine phosphorylase activity" EXACT [EC:2.4.2.4] synonym: "gliostatins" RELATED [EC:2.4.2.4] synonym: "pyrimidine deoxynucleoside phosphorylase activity" EXACT [EC:2.4.2.4] synonym: "pyrimidine phosphorylase activity" BROAD [EC:2.4.2.4] synonym: "thymidine-orthophosphate deoxyribosyltransferase activity" EXACT [EC:2.4.2.4] synonym: "thymidine:phosphate deoxy-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.4] synonym: "thymidine:phosphate deoxy-D-ribosyltransferase activity" EXACT [EC:2.4.2.4] xref: EC:2.4.2.4 xref: GO:0009032 xref: MetaCyc:THYM-PHOSPH-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0002362 name: trimethylamine-N-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O." [EC:1.6.6.9] subset: gosubset_prok synonym: "NADH:trimethylamine-N-oxide oxidoreductase" EXACT [EC:1.6.6.9] synonym: "trimethylamine N-oxide reductase" EXACT [EC:1.6.6.9] synonym: "trimethylamine oxidase activity" EXACT [EC:1.6.6.9] synonym: "trimethylamine oxide reductase" EXACT [EC:1.6.6.9] xref: EC:1.6.6.9 xref: GO:0009033 xref: MetaCyc:TMAOREDUCT-RXN is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0002363 name: tryptophanase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + H2O = indole + pyruvate + NH3." [EC:4.1.99.1] comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step. subset: gosubset_prok synonym: "L-tryptophan indole-lyase (deaminating) activity" EXACT [EC:4.1.99.1] synonym: "L-tryptophan indole-lyase (deaminating; pyruvate forming) activity" EXACT [EC:4.1.99.1] synonym: "L-tryptophan indole-lyase activity" EXACT [EC:4.1.99.1] synonym: "L-tryptophanase activity" EXACT [EC:4.1.99.1] synonym: "TNase activity" EXACT [EC:4.1.99.1] synonym: "tryptophan catabolic process, using tryptophanase" RELATED [EC:4.1.99.1] synonym: "tryptophan catabolism, using tryptophanase" RELATED [EC:4.1.99.1] xref: EC:4.1.99.1 xref: GO:0009034 xref: MetaCyc:TRYPDEG-PWY xref: MetaCyc:TRYPTOPHAN-RXN is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0002364 name: Type I site-specific deoxyribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA." [EC:3.1.21.3, PMID:15788748] subset: gosubset_prok synonym: "adenosine triphosphate-dependent deoxyribonuclease activity" EXACT [EC:3.1.21.3] synonym: "ATP-dependent DNase activity" EXACT [EC:3.1.21.3] synonym: "deoxyribonuclease (adenosine triphosphate-hydrolyzing)" EXACT [EC:3.1.21.3] synonym: "deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)" EXACT [EC:3.1.21.3] synonym: "Type I restriction enzyme activity" EXACT [] synonym: "type I site-specific deoxyribonuclease activity" EXACT [EC:3.1.21.3] xref: EC:3.1.21.3 xref: GO:0009035 xref: MetaCyc:3.1.21.3-RXN is_a: CCO:F0003014 ! restriction endodeoxyribonuclease activity is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002365 name: Type II site-specific deoxyribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site." [EC:3.1.21.4, PMID:12654995] subset: gosubset_prok synonym: "Type II restriction enzyme activity" EXACT [] xref: EC:3.1.21.4 xref: GO:0009036 xref: MetaCyc:3.1.21.4-RXN is_a: CCO:F0003014 ! restriction endodeoxyribonuclease activity is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0002366 name: tyrosine-based site-specific recombinase activity namespace: molecular_function def: "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site." [GOC:elh, PMID:11090626] subset: gosubset_prok synonym: "site-specific tyrosine recombinase activity" EXACT [] synonym: "tyrosine recombinase" BROAD [] xref: GO:0009037 is_a: CCO:F0002244 ! integrase activity is_a: CCO:F0002340 ! site-specific recombinase activity [Term] id: CCO:F0002367 name: undecaprenol kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate." [EC:2.7.1.66] subset: gosubset_prok synonym: "ATP:undecaprenol phosphotransferase activity" EXACT [EC:2.7.1.66] synonym: "C55-isoprenoid alcohol kinase activity" EXACT [EC:2.7.1.66] synonym: "C55-isoprenoid alcohol phosphokinase activity" EXACT [EC:2.7.1.66] synonym: "C55-isoprenyl alcohol phosphokinase activity" EXACT [EC:2.7.1.66] synonym: "isoprenoid alcohol kinase (phosphorylating)" EXACT [EC:2.7.1.66] synonym: "isoprenoid alcohol kinase activity" EXACT [EC:2.7.1.66] synonym: "isoprenoid alcohol phosphokinase activity" EXACT [EC:2.7.1.66] synonym: "isoprenoid-alcohol kinase activity" BROAD [EC:2.7.1.66] synonym: "polyisoprenol kinase activity" EXACT [EC:2.7.1.66] xref: EC:2.7.1.66 xref: GO:0009038 xref: MetaCyc:UNDECAPRENOL-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0002368 name: urease activity namespace: molecular_function def: "Catalysis of the reaction: urea + H2O = CO2 + 2 NH3." [EC:3.5.1.5] subset: gosubset_prok synonym: "urea amidohydrolase activity" EXACT [EC:3.5.1.5] xref: EC:3.5.1.5 xref: GO:0009039 xref: MetaCyc:UREASE-RXN xref: UM-BBD_enzymeID:e0170 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0002369 name: ureidoglycolate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-ureidoglycolate + NADP+ = oxalureate + NADPH + H+." [EC:1.1.1.154] subset: gosubset_prok synonym: "(S)-ureidoglycolate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.154] xref: EC:1.1.1.154 xref: GO:0009040 xref: MetaCyc:R165-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002370 name: uridylate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP." [GOC:go_curators] subset: gosubset_prok xref: EC:2.7.4.- xref: GO:0009041 is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004124 ! nucleotide kinase activity [Term] id: CCO:F0002371 name: valine-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine." [EC:2.6.1.66] subset: gosubset_prok synonym: "alanine--valine transaminase activity" EXACT [EC:2.6.1.66] synonym: "alanine-oxoisovalerate aminotransferase activity" EXACT [EC:2.6.1.66] synonym: "L-valine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.66] synonym: "transaminase C activity" NARROW [EC:2.6.1.66] synonym: "valine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.66] synonym: "valine-pyruvate aminotransferase activity" EXACT [] xref: EC:2.6.1.66 xref: GO:0009042 xref: MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0002372 name: xylan 1,4-beta-xylosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of 1,4-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini." [EC:3.2.1.37] subset: gosubset_prok synonym: "1,4-beta-D-xylan xylohydrolase activity" EXACT [EC:3.2.1.37] synonym: "beta-D-xylopyranosidase activity" EXACT [EC:3.2.1.37] synonym: "beta-xylosidase activity" EXACT [EC:3.2.1.37] synonym: "exo-1,4-beta-D-xylosidase activity" EXACT [EC:3.2.1.37] synonym: "exo-1,4-beta-xylosidase activity" EXACT [EC:3.2.1.37] synonym: "exo-1,4-xylosidase activity" EXACT [EC:3.2.1.37] synonym: "xylobiase activity" EXACT [EC:3.2.1.37] xref: EC:3.2.1.37 xref: GO:0009044 xref: MetaCyc:3.2.1.37-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0002373 name: xylose isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-xylose = D-xylulose." [EC:5.3.1.5] subset: gosubset_prok synonym: "D-xylose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.5] synonym: "D-xylose isomerase activity" EXACT [EC:5.3.1.5] synonym: "D-xylose ketoisomerase activity" EXACT [EC:5.3.1.5] synonym: "D-xylose ketol-isomerase activity" EXACT [EC:5.3.1.5] xref: EC:5.3.1.5 xref: GO:0009045 xref: MetaCyc:XYLISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0002374 name: zinc D-Ala-D-Ala carboxypeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine." [EC:3.4.17.14] synonym: "D-alanyl-D-alanine hydrolase activity" EXACT [EC:3.4.17.14] synonym: "D-alanyl-D-alanine-cleaving carboxypeptidase activity" EXACT [EC:3.4.17.14] synonym: "DD-carboxypeptidase" BROAD [EC:3.4.17.14] synonym: "DD-carboxypeptidase-transpeptidase activity" EXACT [EC:3.4.17.14] synonym: "G enzyme" RELATED [EC:3.4.17.14] synonym: "Zn(2+) G peptidase activity" RELATED [EC:3.4.17.14] synonym: "Zn2+ G peptidase activity" EXACT [EC:3.4.17.14] xref: EC:3.4.17.14 xref: GO:0009046 xref: MetaCyc:3.4.17.14-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0002375 name: aspartic-type signal peptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism." [GOC:mah] subset: gosubset_prok xref: EC:3.4.23.- xref: GO:0009049 is_a: CCO:F0000659 ! aspartic-type endopeptidase activity is_a: CCO:F0002335 ! signal peptidase activity [Term] id: CCO:F0002378 name: electron carrier activity namespace: molecular_function def: "Any molecular entity that serves as an electron acceptor and electron donor in an electron transport system." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: gosubset_prok synonym: "2Fe-2S electron transfer carrier" NARROW [] synonym: "3Fe-4S/4Fe-4S electron transfer carrier" NARROW [] synonym: "adrenodoxin-type ferredoxin" NARROW [] synonym: "amicyanin" NARROW [] synonym: "azurin" NARROW [] synonym: "bacterial-type ferredoxin" NARROW [] synonym: "chloroplast-type ferredoxin" NARROW [] synonym: "copper electron carrier" NARROW [] synonym: "dicluster bacterial-type ferredoxin" NARROW [] synonym: "electron acceptor activity" NARROW [] synonym: "electron carrier, chlorophyll electron transport system" RELATED [] synonym: "electron donor activity" NARROW [] synonym: "electron transfer flavoprotein" NARROW [] synonym: "electron transfer flavoprotein, group I" NARROW [] synonym: "electron transfer flavoprotein, group II" NARROW [] synonym: "electron transporter activity" EXACT [] synonym: "high-potential iron-sulfur carrier" NARROW [] synonym: "iron-sulfur electron transfer carrier" NARROW [] synonym: "monocluster bacterial-type ferredoxin" NARROW [] synonym: "mononuclear iron electron carrier" NARROW [] synonym: "polyferredoxin" NARROW [] synonym: "redox-active disulfide bond electron carrier" NARROW [] synonym: "rubredoxin" NARROW [] synonym: "small blue copper electron carrier" NARROW [] synonym: "thioredoxin-like 2Fe-2S ferredoxin" NARROW [] xref: GO:0009053 xref: GO:0009054 xref: GO:0009055 xref: Reactome:20046 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0002379 name: quorum sensing signal generator activity namespace: molecular_function subset: gosubset_prok xref: GO:0009369 is_a: CCO:F0001225 ! signal transducer activity [Term] id: CCO:F0002380 name: quorum sensing response regulator activity namespace: molecular_function subset: gosubset_prok xref: GO:0009370 is_a: CCO:F0001225 ! signal transducer activity [Term] id: CCO:F0002381 name: biotin binding namespace: molecular_function def: "Interacting selectively with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "vitamin B7 binding" EXACT [] synonym: "vitamin H binding" EXACT [] xref: GO:0009374 is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0002382 name: HslUV protease activity namespace: molecular_function def: "Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins." [GOC:mah, PMID:10368141] subset: gosubset_prok xref: GO:0009377 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0002383 name: four-way junction helicase activity namespace: molecular_function def: "Catalysis of the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions." [GOC:jl, PMID:9442895] subset: gosubset_prok synonym: "Holliday junction helicase activity" NARROW [] xref: GO:0009378 is_a: CCO:F0000275 ! DNA helicase activity [Term] id: CCO:F0002384 name: excinuclease ABC activity namespace: molecular_function subset: gosubset_prok xref: GO:0009381 is_a: CCO:F0000917 ! endodeoxyribonuclease activity [Term] id: CCO:F0002385 name: rRNA (cytosine-C5-967)-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine, at position 967 in the Escherichia coli small subunit ribosomal RNA or the equivalent position in the small subunit rRNA of other species." [PMID:10026269] comment: Note that the term name mentions a specific position within an E. coli RNA because no other names have yet arisen for this activity; the term nevertheless can be used for analogous activities in other species, and the name can be changed if better wording is found. Synonyms that mention positions applicable to other species may also be added. synonym: "rRNA m5C967 methyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0009383 is_a: CCO:F0001756 ! C-methyltransferase activity is_a: CCO:F0003156 ! rRNA (cytosine) methyltransferase activity [Term] id: CCO:F0002386 name: N-acylmannosamine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate." [EC:2.7.1.60] subset: gosubset_prok synonym: "acetylamidodeoxymannokinase activity" EXACT [EC:2.7.1.60] synonym: "acetylmannosamine kinase activity" EXACT [EC:2.7.1.60] synonym: "acylaminodeoxymannokinase activity" EXACT [EC:2.7.1.60] synonym: "acylmannosamine kinase (phosphorylating)" EXACT [EC:2.7.1.60] synonym: "acylmannosamine kinase activity" EXACT [EC:2.7.1.60] synonym: "ATP:N-acetylmannosamine 6-phosphotransferase activity" EXACT [EC:2.7.1.60] synonym: "ATP:N-acyl-D-mannosamine 6-phosphotransferase activity" EXACT [EC:2.7.1.60] synonym: "N-acetylmannosamine kinase activity" EXACT [EC:2.7.1.60] synonym: "N-acyl-D-mannosamine kinase activity" EXACT [EC:2.7.1.60] xref: EC:2.7.1.60 xref: GO:0009384 xref: MetaCyc:N-ACYLMANNOSAMINE-KINASE-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002387 name: N-acylmannosamine-6-phosphate 2-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate." [MetaCyc:NANE-RXN] synonym: "N-acylmannosamine-6-P epimerase activity" EXACT [] xref: EC:5.-.-.- xref: GO:0009385 xref: MetaCyc:NANE-RXN is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0002388 name: dimethyl sulfoxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O." [UM-BBD_enzymeID:e0188] subset: gosubset_prok synonym: "dimethyl sulphoxide reductase activity" EXACT [] xref: EC:1.8.99.- xref: GO:0009389 xref: UM-BBD_enzymeID:e0188 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0002389 name: ribonucleotide reductase activating enzyme activity namespace: molecular_function xref: EC:1.97.1.- xref: GO:0009391 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002390 name: N-acetyl-anhydromuramoyl-L-alanine amidase activity namespace: molecular_function xref: GO:0009392 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0002391 name: receptor signaling protein serine/threonine phosphatase activity namespace: molecular_function synonym: "receptor signalling protein serine/threonine phosphatase activity" EXACT [] xref: GO:0009400 is_a: CCO:F0001087 ! protein serine/threonine phosphatase activity is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0002392 name: cytochrome bo3 ubiquinol oxidase activity namespace: molecular_function xref: EC:1.10.3.- xref: GO:0009486 is_a: CCO:F0002170 ! cytochrome o ubiquinol oxidase activity [Term] id: CCO:F0002393 name: plastoquinol-plastocyanin reductase activity namespace: molecular_function def: "Catalysis of the reaction: plastoquinol-1 + 2 oxidized plastocyanin = plastoquinone + 2 reduced plastocyanin." [EC:1.10.99.1] subset: gosubset_prok synonym: "cytochrome b6f" NARROW [EC:1.10.99.1] synonym: "plastoquinol/plastocyanin oxidoreductase activity" EXACT [EC:1.10.99.1] synonym: "plastoquinol:oxidized-plastocyanin oxidoreductase activity" EXACT [EC:1.10.99.1] xref: EC:1.10.99.1 xref: GO:0009496 xref: MetaCyc:PLASTOQUINOL--PLASTOCYANIN-REDUCTASE-RXN is_a: CCO:F0003270 ! oxidoreductase activity, acting on diphenols and related substances as donors [Term] id: CCO:F0002394 name: zeaxanthin epoxidase activity namespace: molecular_function def: "Catalysis of the reactions: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O and antheraxanthin + NAD(P)H + H+ + O2 = violaxanthin + NAD(P)+ + H2O." [EC:1.14.13.90] synonym: "zea-epoxidase activity" EXACT [EC:1.14.13.90] synonym: "zeaxanthin,NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.14.13.90] xref: EC:1.14.13.90 xref: GO:0009540 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0002395 name: sucrose:monovalent cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in)." [GOC:jy, TC:2.A.2.-.-, TC:2.A.2.4.1] synonym: "sucrose permease activity" RELATED [] xref: GO:0009669 is_a: CCO:F0001968 ! sucrose transmembrane transporter activity is_a: CCO:F0002881 ! glycoside-pentoside-hexuronide:cation symporter activity [Term] id: CCO:F0002396 name: triose-phosphate transmembrane transporter activity namespace: molecular_function def: "Enables the exchange of an organic three carbon compound phosphate ester for inorganic phosphate." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.7.-.-] synonym: "triose phosphate transporter" EXACT [] xref: GO:0009670 xref: GO:0015122 is_a: CCO:F0002622 ! monosaccharide transmembrane transporter activity [Term] id: CCO:F0002397 name: nitrate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in)." [UniProtKB:Q05085] synonym: "nitrate(chlorate):hydrogen symporter activity" EXACT [] synonym: "nitrate(chlorate):proton symporter" EXACT [] xref: GO:0009671 is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0002398 name: auxin:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in)." [PMID:8688077] synonym: "auxin:proton symporter" EXACT [] xref: GO:0009672 is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0002399 name: low affinity phosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of phosphate from one side of the membrane to the other. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [TC:2.A.20.-.-] xref: GO:0009673 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity [Term] id: CCO:F0002400 name: potassium:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in)." [TC:2.A.38.3.1] synonym: "high affinity potassium transporter" RELATED [] xref: GO:0009674 is_a: CCO:F0004258 ! potassium ion symporter activity [Term] id: CCO:F0002401 name: high affinity sulfate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). Transporter with a high affinity for sulfate, that mediates the active uptake of sulfate from areas of low sulfate concentration to high sulfate concentration." [UniProtKB:P53391] synonym: "high affinity sulfate:proton symporter" EXACT [] synonym: "high affinity sulphate:hydrogen symporter activity" EXACT [] xref: GO:0009675 is_a: CCO:F0001965 ! sulfate:hydrogen symporter activity [Term] id: CCO:F0002402 name: low affinity sulfate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). Transporter that mediates the transport of sulfate between cellular or subcellular compartments with a low affinity for hydrogen and sulfate." [PMID:7568135] synonym: "low affinity sulfate:proton symporter" EXACT [] synonym: "low affinity sulphate:hydrogen symporter activity" EXACT [] xref: GO:0009676 is_a: CCO:F0001965 ! sulfate:hydrogen symporter activity [Term] id: CCO:F0002403 name: hydrogen-translocating pyrophosphatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of pyrophosphate, which generates a proton motive force." [GOC:mtg_transport, ISBN:0815340729, TC:3.A.10.-.-] subset: gosubset_prok synonym: "proton-translocating pyrophosphatase activity" EXACT [] xref: GO:0009678 is_a: CCO:F0002826 ! P-P-bond-hydrolysis-driven transmembrane transporter activity is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0002404 name: hexose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in)." [TC:2.A.1.-.-] subset: gosubset_prok synonym: "hexose:proton symporter" EXACT [] xref: GO:0009679 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002405 name: L-arabinokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-arabinose = ADP + beta-L-arabinose 1-phosphate." [EC:2.7.1.46] synonym: "ATP:L-arabinose 1-phosphotransferase activity" EXACT [] synonym: "L-arabinokinase (phosphorylating)" EXACT [EC:2.7.1.46] xref: EC:2.7.1.46 xref: GO:0009702 xref: MetaCyc:L-ARABINOKINASE-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0002406 name: nitrate reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: NO2- (nitrite) + NAD+ + H2O = NO3- (nitrate) + NADH + H+." [EC:1.7.1.1] comment: Note that this function was formerly EC:1.6.6.1. synonym: "assimilatory NADH: nitrate reductase activity" EXACT [EC:1.7.1.1] synonym: "assimilatory NADH:nitrate reductase activity" EXACT [EC:1.7.1.1] synonym: "assimilatory nitrate reductase activity" BROAD [EC:1.7.1.1] synonym: "NADH-dependent nitrate reductase activity" EXACT [EC:1.7.1.1] synonym: "NADH-nitrate reductase activity" EXACT [EC:1.7.1.1] synonym: "NADH:nitrate oxidoreductase activity" EXACT [EC:1.7.1.1] synonym: "NADH:nitrate reductase activity" EXACT [] synonym: "nitrate reductase (NADH(2)) activity" EXACT [EC:1.7.1.1] synonym: "nitrate reductase (NADH2)" EXACT [EC:1.7.1.1] synonym: "nitrite:NAD+ oxidoreductase activity" EXACT [EC:1.7.1.1] xref: EC:1.7.1.1 xref: GO:0009703 xref: MetaCyc:NITRATE-REDUCTASE-(NADH)-RXN is_a: CCO:F0002276 ! nitrate reductase activity is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0002407 name: transmembrane receptor histidine kinase activity namespace: molecular_function def: "A transmembrane receptor that perceives a stimulus and that produces a molecular signal via phosphotransfer at histidine residues." [GOC:lr] subset: gosubset_prok xref: GO:0009784 is_a: CCO:F0001044 ! protein histidine kinase activity is_a: CCO:F0004122 ! transmembrane receptor protein kinase activity [Term] id: CCO:F0002408 name: 1-aminocyclopropane-1-carboxylate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: ascorbate + 1-aminocyclopropane-1-carboxylate + O2 = 2 H2O + ethene (ethylene) + L-dehydro-ascorbate + hydrocyanic acid + CO2." [EC:1.14.17.4, MetaCyc:ETHYL-RXN] synonym: "1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming)" EXACT [EC:1.14.17.4] synonym: "ACC oxidase activity" EXACT [] synonym: "aminocyclopropanecarboxylate oxidase activity" EXACT [EC:1.14.17.4] synonym: "ethene-forming enzyme" BROAD [] synonym: "ethylene-forming enzyme" BROAD [] xref: EC:1.14.17.4 xref: GO:0009815 xref: MetaCyc:ETHYL-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0002409 name: adenylate dimethylallyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: delta(2)-isopentenyl diphosphate + AMP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-monophosphate." [EC:2.5.1.27] synonym: "2-isopentenyl-diphosphate:AMP 2-isopentenyltransferase activity" EXACT [] synonym: "2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase activity" EXACT [EC:2.5.1.27] synonym: "adenylate isopentenyltransferase activity" EXACT [] synonym: "cytokinin synthase activity" EXACT [] synonym: "dimethylallyl-diphosphate:AMP dimethylallyltransferase activity" EXACT [EC:2.5.1.27] synonym: "isopentenyltransferase activity" EXACT [] xref: EC:2.5.1.27 xref: GO:0009824 xref: MetaCyc:ADENYLATE-ISOPENTENYLTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0002410 name: photoreceptor activity namespace: molecular_function def: "The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation." [GOC:ai, GOC:go_curators] subset: gosubset_prok synonym: "blue-sensitive opsin" NARROW [] synonym: "green-sensitive opsin" NARROW [] synonym: "long-wave-sensitive opsin" NARROW [] synonym: "opsin" NARROW [] synonym: "red-sensitive opsin" NARROW [] synonym: "short-wave-sensitive opsin" NARROW [] synonym: "UV-sensitive opsin" NARROW [] synonym: "violet-sensitive opsin" NARROW [] xref: GO:0009881 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0002411 name: blue light photoreceptor activity namespace: molecular_function def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation." [GOC:tb] subset: gosubset_prok xref: GO:0009882 is_a: CCO:F0002410 ! photoreceptor activity [Term] id: CCO:F0002412 name: red or far-red light photoreceptor activity namespace: molecular_function def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation." [GOC:lr] synonym: "red/far-red light photoreceptor activity" EXACT [] xref: GO:0009883 is_a: CCO:F0002410 ! photoreceptor activity [Term] id: CCO:F0002413 name: cytokinin receptor activity namespace: molecular_function def: "Combining with a cytokinin to initiate a change in cell activity." [GOC:lr] xref: GO:0009884 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0002414 name: transmembrane histidine kinase cytokinin receptor activity namespace: molecular_function def: "A transmembrane receptor of cytokinins that produces a molecular signal via phosphotransfer at histidine residues." [GOC:lr] xref: GO:0009885 is_a: CCO:F0002407 ! transmembrane receptor histidine kinase activity is_a: CCO:F0002413 ! cytokinin receptor activity [Term] id: CCO:F0002415 name: ent-kaurene synthase activity namespace: molecular_function def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-kaurene + diphosphate." [EC:4.2.3.19, ISBN:0943088399] synonym: "ent-copalyl-diphosphate diphosphate-lyase (cyclizing)" EXACT [EC:4.2.3.19] synonym: "ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming)" EXACT [EC:4.2.3.19] synonym: "ent-kaurene synthase B activity" NARROW [EC:4.2.3.19] synonym: "ent-kaurene synthetase B activity" NARROW [EC:4.2.3.19] xref: EC:4.2.3.19 xref: GO:0009899 xref: MetaCyc:4.2.3.19-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0002416 name: ent-copalyl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranylgeranyl diphosphate = ent-copalyl diphosphate." [EC:5.5.1.13, ISBN:0943088399] synonym: "diterpene cyclase activity" BROAD [] synonym: "ent-copalyl-diphosphate lyase (decyclizing)" EXACT [EC:5.5.1.13] synonym: "ent-kaurene synthase A activity" NARROW [EC:5.5.1.13] synonym: "ent-kaurene synthetase A activity" NARROW [EC:5.5.1.13] xref: EC:5.5.1.13 xref: GO:0009905 xref: MetaCyc:5.5.1.13-RXN is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0002417 name: alternative oxidase activity namespace: molecular_function def: "Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product." [ISBN:0943088399] xref: GO:0009916 is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0002418 name: sterol 5-alpha reductase activity namespace: molecular_function def: "Catalysis of the removal of a C-5 double bond in the B ring of a sterol." [ISBN:0943088399] xref: GO:0009917 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0002419 name: sterol delta7 reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol." [ISBN:0943088399] synonym: "sterol delta-7 reductase activity" EXACT [] xref: GO:0009918 xref: MetaCyc:RXN-707 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0002420 name: fatty acid elongase activity namespace: molecular_function def: "Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C)." [GOC:tb] xref: GO:0009922 is_a: CCO:F0000733 ! fatty-acid synthase activity [Term] id: CCO:F0002421 name: octadecanal decarbonylase activity namespace: molecular_function def: "Catalysis of the reaction: octadecanal = heptadecane + CO." [EC:4.1.99.5, GOC:tb] synonym: "aldehyde decarbonylase activity" EXACT [] synonym: "decarbonylase activity" EXACT [EC:4.1.99.5] synonym: "octadecanal alkane-lyase activity" EXACT [] xref: EC:4.1.99.5 xref: GO:0009924 xref: MetaCyc:OCTADECANAL-DECARBONYLASE-RXN is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0002422 name: histidine phosphotransfer kinase activity namespace: molecular_function def: "Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator." [PMID:11842140] subset: gosubset_prok xref: GO:0009927 is_a: CCO:F0001225 ! signal transducer activity is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0002423 name: calcium-dependent protein serine/threonine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of calcium ions." [GOC:mah] xref: GO:0009931 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0002424 name: amino-terminal vacuolar sorting propeptide binding namespace: molecular_function def: "Interacting selectively with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin coated vesicles." [GOC:sm, PMID:10871276] xref: GO:0009940 is_a: CCO:F0002447 ! vacuolar sorting signal binding [Term] id: CCO:F0002425 name: adenylyl-sulfate reductase activity namespace: molecular_function def: "Catalysis of the reaction: AMP + SO3(2-) (sulfite) + acceptor = adenylyl sulfate + reduced acceptor." [EC:1.8.99.2, PMID:5421934] subset: gosubset_prok synonym: "adenosine 5'-phosphosulfate reductase" EXACT [EC:1.8.99.2] synonym: "adenosine phosphosulfate reductase activity" EXACT [EC:1.8.99.2] synonym: "adenylyl-sulphate reductase activity" EXACT [EC:1.8.99.2] synonym: "AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.99.2] synonym: "AMP, sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.99.2] synonym: "APS reductase activity" EXACT [EC:1.8.99.2] synonym: "APS-reductase" EXACT [EC:1.8.99.2] xref: EC:1.8.99.2 xref: GO:0009973 xref: MetaCyc:ADENYLYLSULFATE-REDUCTASE-RXN is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0002426 name: epsilon hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of zeinoxanthin to lutein. Adds hydroxy group to the epsilon ring of the alpha-carotene." [PMID:8837513] xref: GO:0009974 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002427 name: cyclase activity namespace: molecular_function def: "Catalysis of a ring closure reaction." [ISBN:0198547684] subset: goslim_pir subset: gosubset_prok xref: GO:0009975 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0002428 name: tocopherol cyclase activity namespace: molecular_function def: "Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol)." [PMID:12213958] xref: GO:0009976 is_a: CCO:F0002427 ! cyclase activity [Term] id: CCO:F0002429 name: proton motive force dependent protein transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of proteins from one side of the membrane to the other. Transportation is dependent on pH gradient across the membrane." [PMID:11526245] synonym: "delta-pH-dependent protein transporter activity" EXACT [] synonym: "pH-dependent protein transporter activity" EXACT [] xref: GO:0009977 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity [Term] id: CCO:F0002430 name: allene oxide synthase activity namespace: molecular_function def: "Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O." [EC:4.2.1.92, MetaCyc:RXN1F-19, PMID:9778849] synonym: "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]" RELATED [EC:4.2.1.92] synonym: "HPI" RELATED [EC:4.2.1.92] synonym: "linoleate hydroperoxide isomerase" RELATED [EC:4.2.1.92] synonym: "linoleic acid hydroperoxide isomerase" RELATED [EC:4.2.1.92] xref: GO:0009978 xref: MetaCyc:RXN1F-19 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0002431 name: 16:0 monogalactosyldiacylglycerol desaturase activity namespace: molecular_function xref: GO:0009979 is_a: CCO:F0005667 ! omega-3 fatty acid desaturase activity [Term] id: CCO:F0002432 name: glutamate carboxypeptidase activity namespace: molecular_function def: "Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups." [EC:3.4.17.11, MetaCyc:3.4.17.11-RXN] subset: gosubset_prok synonym: "carboxypeptidase G activity" BROAD [EC:3.4.17.11] synonym: "carboxypeptidase G1 activity" RELATED [EC:3.4.17.11] synonym: "carboxypeptidase G2 activity" RELATED [EC:3.4.17.11] synonym: "glutamyl carboxypeptidase activity" EXACT [EC:3.4.17.11] synonym: "N-pteroyl-L-glutamate hydrolase activity" EXACT [EC:3.4.17.11] xref: EC:3.4.17.11 xref: GO:0009980 xref: MetaCyc:3.4.17.11-RXN is_a: CCO:F0000649 ! carboxypeptidase activity [Term] id: CCO:F0002433 name: pseudouridine synthase activity namespace: molecular_function def: "Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5." [EC:5.4.99.12, GOC:mah] comment: Note that this term should not be confused with 'pseudouridylate synthase activity ; GO:0004730', which refers to the formation of free pseudouridine from uracil and ribose-5-phosphate. subset: gosubset_prok synonym: "transfer ribonucleate pseudouridine synthetase activity" NARROW [EC:5.4.99.12] synonym: "transfer RNA pseudouridine synthetase activity" NARROW [EC:5.4.99.12] synonym: "tRNA pseudouridylate synthase I activity" NARROW [EC:5.4.99.12] synonym: "tRNA-pseudouridine synthase activity" NARROW [] synonym: "tRNA-pseudouridine synthase I activity" NARROW [] synonym: "tRNA-uridine isomerase activity" NARROW [EC:5.4.99.12] synonym: "tRNA-uridine uracilmutase activity" NARROW [EC:5.4.99.12] xref: EC:5.4.99.12 xref: GO:0009982 xref: GO:0016439 xref: MetaCyc:TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0002434 name: tyrosine aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of N-terminal tyrosine from a peptide." [GOC:sm, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0009983 is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0002435 name: dihydroflavonol(thiole) lyase activity namespace: molecular_function xref: GO:0009985 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0002436 name: auxin binding namespace: molecular_function def: "Interacting selectively with auxin, plant hormones that regulate aspects of plant growth." [GOC:sm] synonym: "auxin receptor" NARROW [] xref: GO:0010011 is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0002437 name: steroid 22-alpha hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O." [GOC:tb] xref: GO:0010012 is_a: CCO:F0001866 ! steroid hydroxylase activity [Term] id: CCO:F0002438 name: N-1-naphthylphthalamic acid binding namespace: molecular_function def: "Interacting selectively with N-1-naphthylphthalamic acid, an auxin transport inhibitor." [GOC:sm] xref: GO:0010013 is_a: CCO:F0001746 ! drug binding [Term] id: CCO:F0002439 name: nucleoside transmembrane transporter activity, against a concentration gradient namespace: molecular_function def: "Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient." [GOC:tb] synonym: "concentrative nucleoside transporter" EXACT [] xref: GO:0010174 is_a: CCO:F0001567 ! nucleoside transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002440 name: sphingosine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of amino alcohol sphingosine from one side of the membrane to the other." [GOC:tb] xref: GO:0010175 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0003013 ! alcohol transmembrane transporter activity [Term] id: CCO:F0002441 name: homogentisate phytyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: homogentisic acid + phytyl diphosphate -> 2-methyl-6-phytylplastoquinol." [PMID:14512521] xref: GO:0010176 is_a: CCO:F0002489 ! homogentisate prenyltransferase activity [Term] id: CCO:F0002442 name: methylthioalkylmalate synthase activity namespace: molecular_function def: "Catalysis of the reaction: w-methylthio-2-oxoalkanoic acid + acetyl-CoA + H2O = 2-(w-methylthio)alkylmalate + CoA." [GOC:pz] xref: GO:0010177 is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0002443 name: IAA-amino acid conjugate hydrolase activity namespace: molecular_function def: "Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid." [GOC:tb] xref: GO:0010178 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0002444 name: IAA-Ala conjugate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: IAA-alanine -> indole-3-acetic acid + alanine." [GOC:tb] xref: GO:0010179 is_a: CCO:F0002443 ! IAA-amino acid conjugate hydrolase activity [Term] id: CCO:F0002445 name: thioglucosidase binding activity namespace: molecular_function def: "Interacting selectively with the enzyme thioglucosidase." [GOC:tb] synonym: "myrosinase binding activity" EXACT [] xref: GO:0010180 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0002446 name: FMN binding namespace: molecular_function def: "Interacting selectively with FMN, flavin mononucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:tb] subset: gosubset_prok synonym: "flavin mononucleotide binding" EXACT [] xref: GO:0010181 is_a: CCO:F0000031 ! nucleotide binding is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0002447 name: vacuolar sorting signal binding namespace: molecular_function def: "Interacting selectively with a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole." [GOC:mah] xref: GO:0010209 is_a: CCO:F0001368 ! signal sequence binding [Term] id: CCO:F0002448 name: IAA-Phe conjugate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: IAA-phenylalanine -> indole-3-acetic acid + phenylalanine." [GOC:syr] xref: GO:0010210 is_a: CCO:F0002443 ! IAA-amino acid conjugate hydrolase activity [Term] id: CCO:F0002449 name: IAA-Leu conjugate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: IAA-leucine -> indole-3-acetic acid + leucine." [GOC:syr] xref: GO:0010211 is_a: CCO:F0002443 ! IAA-amino acid conjugate hydrolase activity [Term] id: CCO:F0002450 name: ent-kaurene oxidase activity namespace: molecular_function def: "Catalysis of three successive oxidations of the 4-methyl group of ent-kaurene resulting in kaurenoic acid." [GOC:tb] synonym: "ent-kaur-16-ene,NADPH:oxygen oxidoreductase (hydroxylating) activity" EXACT [] xref: EC:1.14.13.78 xref: GO:0010241 xref: MetaCyc:1.14.13.78-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0002451 name: oxygen evolving activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle." [GOC:kd, GOC:syr, PMID:17091926, PMID:7948862] synonym: "photosynthetic water oxidation" EXACT [] xref: GO:0010242 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002452 name: phytol kinase activity namespace: molecular_function def: "Catalysis of the reaction: phytol + CTP = phytylphosphate + CDP." [PMID:16361393] xref: GO:0010276 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0002453 name: chlorophyllide a oxygenase activity namespace: molecular_function def: "Catalysis of hydroxylation at the 7-methyl group of chlorophyllide a, according to the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+ and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+." [EC:1.13.12.14, MetaCyc:RXN-7677] synonym: "CAO" RELATED [EC:1.13.12.14] synonym: "chlorophyll a oxygenase activity" EXACT [] synonym: "chlorophyll b synthetase activity" EXACT [] synonym: "chlorophyllide a:oxygen 7-oxidoreductase activity" EXACT [EC:1.13.12.14] synonym: "chlorophyllide-a oxygenase activity" EXACT [EC:1.13.12.14] synonym: "cholorophyll-b synthase activity" EXACT [EC:1.13.12.14] xref: EC:1.13.12.14 xref: GO:0010277 xref: GO:0046407 is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) [Term] id: CCO:F0002454 name: indole-3-acetic acid amido synthetase namespace: molecular_function def: "Catalysis of the reaction IAA + an amino acid = an IAA amide conjugate." [PMID:15659623] synonym: "IAA amido synthetase activity" EXACT [] xref: GO:0010279 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0002455 name: UDP-L-rhamnose synthase activity namespace: molecular_function def: "Catalysis of the reaction UDP-D-glucose + NADPH = UDP-L-rhamnose + NADP+ + H2O." [GOC:tair_curators, PMID:14701918] synonym: "UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase-4-reductase activity" EXACT [] xref: GO:0010280 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0002456 name: pinoresinol reductase activity namespace: molecular_function def: "Catalysis of the reaction: pinoresinol + NADPH = lariciresinol + NADP+." [PMID:10066819, PMID:7592828] xref: GO:0010283 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002457 name: lariciresinol reductase activity namespace: molecular_function def: "Catalysis of the reaction: lariciresinol + NADPH = secoisolariciresinol + NADP+." [PMID:10066819, PMID:7592828] xref: GO:0010284 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002458 name: L,L-diaminopimelate aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: LL-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O." [PMID:16361515] synonym: "LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity" EXACT [] synonym: "LL-DAP aminotransferase activity" EXACT [EC:2.6.1.83] synonym: "LL-DAP-AT activity" EXACT [EC:2.6.1.83] synonym: "LL-diaminopimelate aminotransferase activity" EXACT [] synonym: "LL-diaminopimelate transaminase activity" EXACT [EC:2.6.1.83] xref: EC:2.6.1.83 xref: GO:0010285 xref: GO:0043742 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0002459 name: chlorophyll catabolite transporter activity namespace: molecular_function def: "Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), into, out of, within or between cells." [PMID:9681016] xref: GO:0010290 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0002460 name: carotene beta-ring hydroxylase activity namespace: molecular_function def: "Catalysis of C3-hydroxylation reaction of the beta-ring of various carotenes." [PMID:16492736] xref: GO:0010291 is_a: CCO:F0000894 ! monooxygenase activity [Term] id: CCO:F0002461 name: GTP:GDP antiporter activity namespace: molecular_function def: "Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out)." [PMID:10514379, PMID:12553910, PMID:16553903] xref: GO:0010292 is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0002462 name: abscisic aldehyde oxidase activity namespace: molecular_function def: "Catalysis of the reaction: abscisic aldehyde + H2O + O2 = abscisate + H2O2." [EC:1.2.3.14, PMID:11050171] synonym: "AAO3" RELATED [EC:1.2.3.14] synonym: "abscisic-aldehyde oxidase activity" EXACT [EC:1.2.3.14] synonym: "abscisic-aldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.14] synonym: "AOdelta" RELATED [EC:1.2.3.14] xref: EC:1.2.3.14 xref: GO:0010293 xref: GO:0033725 is_a: CCO:F0003685 ! aryl-aldehyde oxidase activity [Term] id: CCO:F0002463 name: abscisic acid glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ABA + UDP-D-glucose = ABA-glucose ester + UDP." [DOI:10.1016/j.tetasy.2004.11.062] xref: GO:0010294 xref: MetaCyc:PWY-5272 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0002465 name: prenylcysteine methylesterase activity namespace: molecular_function def: "Catalysis of the reaction: protein prenyl L-cysteine methylester + H2O = protein L-cysteine + methanol." [PMID:16870359] xref: GO:0010296 is_a: CCO:F0008164 ! protein methylesterase activity [Term] id: CCO:F0002466 name: heteroglycan binding namespace: molecular_function def: "Interacting selectively with heteroglycans." [PMID:16640603] xref: GO:0010297 is_a: CCO:F0004357 ! polysaccharide binding [Term] id: CCO:F0002467 name: dihydrocamalexic acid decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2." [PMID:16766671] xref: GO:0010298 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0002468 name: xanthoxin dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: xanthoxin + NAD+ = abscisic aldehyde + NADH + H+." [EC:1.1.1.288, PMID:12172025] synonym: "ABA2" RELATED [EC:1.1.1.288] synonym: "xanthoxin oxidase activity" EXACT [EC:1.1.1.288] synonym: "xanthoxin:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.288] xref: EC:1.1.1.288 xref: GO:0010301 xref: GO:0033710 is_a: CCO:F0000500 ! alcohol dehydrogenase activity [Term] id: CCO:F0002469 name: 2-oxoglutarate-dependent dioxygenase activity namespace: molecular_function def: "Hydroxylase, with 2-oxoglutarate as one donor, and incorporation or reduction of one atom each of oxygen into both donors." [EC:1.14.11.-, PMID:16140259] xref: GO:0010302 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0002470 name: limit dextrinase activity namespace: molecular_function def: "Catalysis of the hydrolysis of (16)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan." [EC:3.2.1.142] synonym: "amylopectin-1,6-glucosidase activity" EXACT [EC:3.2.1.142] synonym: "dextrin alpha-1,6-glucanohydrolase activity" EXACT [EC:3.2.1.142] synonym: "R-enzyme" RELATED [EC:3.2.1.142] xref: EC:3.2.1.142 xref: GO:0010303 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0002471 name: acetylglutamate kinase regulator activity namespace: molecular_function def: "Modulates the enzyme activity of acetylglutamate kinase." [PMID:16377628] xref: GO:0010307 is_a: CCO:F0004130 ! kinase regulator activity [Term] id: CCO:F0002472 name: acireductone dioxygenase (Ni2+-requiring) activity namespace: molecular_function def: "Catalysis of reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + formate + CO." [EC:1.13.11.53, PMID:16297065] synonym: "1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)" EXACT [EC:1.13.11.53] synonym: "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase activity" BROAD [EC:1.13.11.53] synonym: "acireductone dioxygenase activity" BROAD [EC:1.13.11.53] synonym: "ARD activity" RELATED [EC:1.13.11.53] synonym: "E-2 activity" RELATED [EC:1.13.11.53] xref: EC:1.13.11.53 xref: GO:0010308 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0002473 name: acireductone dioxygenase [iron(II)-requiring] activity namespace: molecular_function def: "Catalysis of reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 4-(methylthio)-2-oxobutanoate + formate." [EC:1.13.11.54, PMID:16297065] subset: gosubset_prok synonym: "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity" EXACT [] synonym: "1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)" EXACT [EC:1.13.11.54] synonym: "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase" BROAD [] synonym: "aci-reductone dioxygenase" BROAD [] synonym: "acireductone dioxygenase (Fe2+-requiring) activity" EXACT [] synonym: "acireductone dioxygenase activity" BROAD [EC:1.13.11.54] synonym: "ARD'" RELATED [] synonym: "ARD1" RELATED [] synonym: "E-2'" RELATED [] xref: EC:1.13.11.54 xref: GO:0010309 xref: MetaCyc:R147-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0002474 name: phytochrome binding namespace: molecular_function def: "Interacting selectively with phytochrome." [PMID:15486102] xref: GO:0010313 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0002475 name: phosphatidylinositol-5-phosphate binding namespace: molecular_function def: "Interacting selectively with phosphatidylinositol-5-phosphate, a phosphorylated derivative of phosphatidylinositol." [GOC:tair_curators] xref: GO:0010314 is_a: CCO:F0005562 ! phosphoinositide binding [Term] id: CCO:F0002477 name: methionine-oxo-acid transaminase activity namespace: molecular_function def: "Catalyzes the reaction: methionine + a 2-oxo acid = 4-methylthio-2-oxobutyrate + an amino acid." [PMID:17056707] xref: GO:0010326 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0002478 name: acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity namespace: molecular_function def: "Catalyzes the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate." [PMID:17163883] synonym: "hexenol acetyltransferase" RELATED [] xref: GO:0010327 is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0002479 name: auxin influx transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of auxin, from one side of a membrane to the other, into a cell." [PMID:16839804] synonym: "auxin influx facilitator" RELATED [] xref: GO:0010328 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0002480 name: auxin efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of auxin, from one side of a membrane to the other, out of a cell." [PMID:16839804] synonym: "auxin efflux carrier" RELATED [] synonym: "auxin efflux facilitator" RELATED [] xref: GO:0010329 is_a: CCO:F0002942 ! efflux transmembrane transporter activity is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0002481 name: gibberellin binding activity namespace: molecular_function def: "Interacting selectively with gibberellins, plant hormones that regulate aspects of plant growth." [GOC:tair_curators] synonym: "gibberellic acid receptor" RELATED [] synonym: "gibberellin receptor" RELATED [] xref: GO:0010331 is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0002482 name: terpene synthase activity namespace: molecular_function def: "Catalyzing the formation of cyclic terpenes through the cyclization of linear terpenes containing varying quantities of isoprene units (i.e. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP)." [EC:4.2.3., GOC:tair_curators] xref: GO:0010333 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0002483 name: sesquiterpene synthase activity namespace: molecular_function def: "Catalyzing the formation of sesquiterpenes (terpene containing 15 carbons, i.e. three isoprene units) through the cyclization of trans,trans-farnesyl diphosphate (an allylic prenyl diphosphate intermediates of the terpene biosynthesis pathway)." [EC:4.2.3.-, GOC:tair_curators] xref: GO:0010334 is_a: CCO:F0002482 ! terpene synthase activity [Term] id: CCO:F0002484 name: carboxyl-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester." [PMID:17220201] xref: GO:0010340 is_a: CCO:F0001758 ! O-methyltransferase activity [Term] id: CCO:F0002485 name: gibberellin carboxyl-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + GA = S-adenosyl-L-homocysteine + GA methyl ester." [PMID:17220201] xref: GO:0010341 is_a: CCO:F0002484 ! carboxyl-O-methyltransferase activity [Term] id: CCO:F0002486 name: L-galactose-1-phosphate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate." [PMID:15550539, PMID:16595667] xref: GO:0010347 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0002487 name: lithium:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in)." [PMID:17270011] xref: GO:0010348 is_a: CCO:F0001614 ! monovalent cation:proton antiporter activity [Term] id: CCO:F0002488 name: L-galactose dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+." [PMID:12047629] synonym: "L-galactose 1-dehydrogenase activity" RELATED [] xref: GO:0010349 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002489 name: homogentisate prenyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid." [PMID:16989822] xref: GO:0010354 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0002490 name: homogentisate farnesyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: homogentisic acid + farnesyl diphosphate -> 2-methyl-6-farnesylplastoquinol." [PMID:16989822] xref: GO:0010355 is_a: CCO:F0002489 ! homogentisate prenyltransferase activity [Term] id: CCO:F0002491 name: homogentisate geranylgeranyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate -> 2-methyl-6-geranylgeranylplastoquinol." [PMID:16989822] xref: GO:0010356 is_a: CCO:F0002489 ! homogentisate prenyltransferase activity [Term] id: CCO:F0002492 name: homogentisate solanesyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: homogentisic acid + solanesyl diphosphate -> 2-methyl-6-solanesylplastoquinol." [PMID:16989822] xref: GO:0010357 is_a: CCO:F0002489 ! homogentisate prenyltransferase activity [Term] id: CCO:F0002493 name: double-stranded methylated DNA binding namespace: molecular_function def: "Interacting selectively with double-stranded methylated DNA. Cytosine methylation in DNA is an important mechanism for establishing stable heritable epigenetic marks." [PMID:17242155] xref: GO:0010385 is_a: CCO:F0000282 ! double-stranded DNA binding [Term] id: CCO:F0002494 name: polyprenyldihydroxybenzoate methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-polyprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-polyprenyl-4-hydroxy-5-methoxybenzoate (or 3-polyprenyl-5-hydroxy-4-methoxybenzoate)." [PMID:9628017] xref: GO:0010420 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0002495 name: abscisic acid binding activity namespace: molecular_function def: "Interacting selectively with abscisic acid, plant hormones that regulate aspects of plant growth." [PMID:17347412] synonym: "ABA binding activity" RELATED [] synonym: "abscisate binding activity" RELATED [] xref: GO:0010427 is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0002496 name: methyl-CpNpG binding namespace: molecular_function def: "Interacting selectively with a methylated cytosine/unspecified/guanine trinucleotide." [PMID:17239600] xref: GO:0010428 is_a: CCO:F0000031 ! nucleotide binding [Term] id: CCO:F0002497 name: methyl-CpNpN binding namespace: molecular_function def: "Interacting selectively with a methylated cytosine/unspecified/unspecified trinucleotide." [PMID:17239600] xref: GO:0010429 is_a: CCO:F0000031 ! nucleotide binding [Term] id: CCO:F0002498 name: 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid (OPC-8:0) + CoA = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)- cyclopentane-1-octanoyl-CoA." [PMID:16963437] synonym: "OPC-8:0 CoA ligase activity" RELATED [] xref: GO:0010435 is_a: CCO:F0003128 ! CoA-ligase activity [Term] id: CCO:F0002499 name: carotenoid dioxygenase activity namespace: molecular_function def: "Catalysis of the oxidative cleavage of carotenoids." [PMID:16459333] synonym: "carotenoid-cleaving dioxygenase" RELATED [] xref: GO:0010436 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0002500 name: 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity namespace: molecular_function def: "Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond." [PMID:16459333] xref: GO:0010437 is_a: CCO:F0002499 ! carotenoid dioxygenase activity [Term] id: CCO:F0002501 name: light-activated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens in response to a light stimulus." [GOC:dph, GOC:tb] xref: GO:0010461 is_a: CCO:F0001492 ! ion channel activity [Term] id: CCO:F0002502 name: nerve growth factor receptor activity namespace: molecular_function def: "Combining with nerve growth factor, to block apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity." [GOC:dph, GOC:tb] xref: GO:0010465 is_a: CCO:F0001357 ! neurotrophin receptor activity [Term] id: CCO:F0002503 name: GDP-galactose:mannose-1-phosphate guanyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-galactose-1-phosphate + mannose-1-phosphate = galactose-1-phosphate + GDP-mannose." [PMID:17485667] xref: GO:0010471 is_a: CCO:F0002242 ! mannose-phosphate guanylyltransferase activity [Term] id: CCO:F0002504 name: GDP-galactose:glucose-1-phosphate guanyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-galactose-1-phosphate + glucose-1-phosphate = galactose-1-phosphate + GDP-glucose." [PMID:17485667] xref: GO:0010472 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002505 name: GDP-galactose:myoinositol-1-phosphate guanyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-galactose-1-phosphate + myoinositol-1-phosphate = galactose-1-phosphate + GDP-myoinositol." [PMID:17485667] xref: GO:0010473 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002506 name: glucose-1-phosphate guanylyltransferase (GDP) activity namespace: molecular_function def: "Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose." [PMID:17462988] synonym: "GDP:Glucose-1- phosphate guanyltransferase activity " EXACT [] xref: GO:0010474 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002507 name: galactose-1-phosphate guanylyltransferase (GDP) activity namespace: molecular_function def: "Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose." [PMID:17462988] xref: GO:0010475 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0002508 name: H3 histone acetyltransferase activity namespace: molecular_function def: "Catalysis of the addition of an acetyl group to a histone, specific for histones H3." [PMID:17877703] xref: GO:0010484 is_a: CCO:F0000815 ! H3/H4 histone acetyltransferase activity [Term] id: CCO:F0002509 name: H4 histone acetyltransferase activity namespace: molecular_function def: "Catalysis of the addition of an acetyl group to a histone, specific for histones H4." [PMID:17877703] xref: GO:0010485 is_a: CCO:F0000815 ! H3/H4 histone acetyltransferase activity [Term] id: CCO:F0002510 name: manganese:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in)." [PMID:17559518] xref: GO:0010486 is_a: CCO:F0008064 ! metal ion:hydrogen antiporter activity [Term] id: CCO:F0002511 name: thermospermine synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + thermospermine." [PMID:17560575] xref: GO:0010487 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0002512 name: UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP." [PMID:17630273] xref: GO:0010488 is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0002513 name: UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-4-keto-6-deoxyglucose -> UDP-4-keto-rhamnose." [GOC:tair_curators, PMID:17190829] xref: GO:0010489 is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0002514 name: UDP-4-keto-rhamnose-4-keto-reductase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH -> UDP-rhamnose + NADP+." [GOC:tair_curators, PMID:17190829] xref: GO:0010490 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002515 name: UTP:arabinose-1-phosphate uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate." [PMID:17341835] xref: GO:0010491 is_a: CCO:F0008184 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity [Term] id: CCO:F0002516 name: telomerase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence." [GOC:dph, GOC:krc, GOC:tb] xref: GO:0010521 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0002517 name: Hsp27 protein regulator activity namespace: molecular_function def: "Modulates the activity of the Hsp27 molecular chaperone." [GOC:dph, GOC:tb, PMID:11546764] xref: GO:0010538 is_a: CCO:F0004341 ! chaperone regulator activity [Term] id: CCO:F0002518 name: Hsp27 protein inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the Hsp27 molecular chaperone." [GOC:dph, GOC:tb] xref: GO:0010539 is_a: CCO:F0002517 ! Hsp27 protein regulator activity is_a: CCO:F0004343 ! chaperone inhibitor activity [Term] id: CCO:F0002519 name: nitrate efflux transmembrane transporter activity namespace: molecular_function xref: GO:0010542 is_a: CCO:F0002591 ! nitrite transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity [Term] id: CCO:F0002520 name: Hsp90 protein regulator activity namespace: molecular_function def: "Binds to and modulates the activity of the molecular chaperone Hsp90." [GOC:dph, GOC:tb, PMID:11146632] xref: GO:0010545 is_a: CCO:F0004341 ! chaperone regulator activity is_a: CCO:F0008202 ! Hsp90 protein binding [Term] id: CCO:F0002521 name: Hsp90 protein inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the Hsp90 molecular chaperone." [GOC:dph, GOC:tb, PMID:11146632] xref: GO:0010546 is_a: CCO:F0002520 ! Hsp90 protein regulator activity is_a: CCO:F0004343 ! chaperone inhibitor activity [Term] id: CCO:F0002522 name: heme-copper terminal oxidase activity namespace: molecular_function def: "Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane." [GOC:kd] subset: gosubset_prok synonym: "haem-copper terminal oxidase activity" EXACT [] xref: GO:0015002 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002524 name: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein." [EC:2.4.1.135] synonym: "glucuronosyltransferase I activity" NARROW [EC:2.4.1.135] synonym: "UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity" EXACT [EC:2.4.1.135] synonym: "UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity" EXACT [EC:2.4.1.135] synonym: "uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity" EXACT [EC:2.4.1.135] xref: EC:2.4.1.135 xref: GO:0015018 xref: MetaCyc:2.4.1.135-RXN is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0002525 name: heparan-alpha-glucosaminide N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide." [EC:2.3.1.78] synonym: "acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity" EXACT [EC:2.3.1.78] synonym: "acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity" EXACT [EC:2.3.1.78] synonym: "heparin-alpha-glucosaminide N-acetyltransferase activity" RELATED [] xref: EC:2.3.1.78 xref: GO:0015019 xref: MetaCyc:2.3.1.78-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0002526 name: glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside." [EC:2.4.1.17] synonym: "1-naphthol glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "1-naphthol-UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "17-beta-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "17-OH steroid UDPGT activity" NARROW [EC:2.4.1.17] synonym: "17beta-hydroxysteroid UDP-glucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "3-OH androgenic UDPGT activity" NARROW [EC:2.4.1.17] synonym: "3alpha-hydroxysteroid UDP-glucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "4-hydroxybiphenyl UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "4-methylumbelliferone UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "4-nitrophenol UDP-glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "4-nitrophenol UDPGT activity" NARROW [EC:2.4.1.17] synonym: "bilirubin glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "bilirubin monoglucuronide glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "bilirubin UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "bilirubin UDPGT activity" NARROW [EC:2.4.1.17] synonym: "bilirubin uridine diphosphoglucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "ciramadol UDP-glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "estriol UDPglucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "estrone UDPglucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "GT activity" EXACT [EC:2.4.1.17] synonym: "morphine glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "p-hydroxybiphenyl UDP glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "p-nitrophenol UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "p-nitrophenol UDP-glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "p-nitrophenylglucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "p-phenylphenol glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "phenyl-UDP-glucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "Phenyl-UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "PNP-UDPGT" RELATED [EC:2.4.1.17] synonym: "pnp-UDPGT activity" NARROW [EC:2.4.1.17] synonym: "UDP glucuronate-estradiol-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "UDP glucuronate-estriol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "UDP glucuronic acid transferase activity" EXACT [EC:2.4.1.17] synonym: "UDP glucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "UDP glucuronyltransferase activity" EXACT [EC:2.4.1.17] synonym: "UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)" EXACT [EC:2.4.1.17] synonym: "UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "UDP-glucuronate-bilirubin glucuronyltransferase activity" NARROW [EC:2.4.1.17] synonym: "UDP-glucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "UDP-glucuronyltransferase activity" EXACT [EC:2.4.1.17] synonym: "UDPGA transferase activity" EXACT [EC:2.4.1.17] synonym: "UDPGA-glucuronyltransferase activity" EXACT [EC:2.4.1.17] synonym: "UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity" EXACT [EC:2.4.1.17] synonym: "UDPGT activity" EXACT [EC:2.4.1.17] synonym: "uridine 5'-diphosphoglucuronyltransferase activity" EXACT [EC:2.4.1.17] synonym: "uridine diphosphate glucuronyltransferase activity" EXACT [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "uridine diphosphoglucuronate-estriol glucuronosyltransferase activity" NARROW [EC:2.4.1.17] synonym: "uridine diphosphoglucuronosyltransferase activity" EXACT [EC:2.4.1.17] synonym: "uridine diphosphoglucuronyltransferase activity" EXACT [EC:2.4.1.17] xref: EC:2.4.1.17 xref: GO:0003981 xref: GO:0015020 xref: MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN xref: Reactome:9978 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0002527 name: heparin-sulfate lyase activity namespace: molecular_function def: "Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar." [EC:4.2.2.8] subset: gosubset_prok synonym: "[heparan sulfate]-sulfate lyase activity" RELATED [] synonym: "heparin-sulfate eliminase activity" RELATED [EC:4.2.2.8] synonym: "heparin-sulphate lyase activity" EXACT [] synonym: "heparitin-sulfate lyase activity" EXACT [] synonym: "heparitinase I" RELATED [EC:4.2.2.8] synonym: "heparitinase II" RELATED [EC:4.2.2.8] xref: EC:4.2.2.8 xref: GO:0015021 xref: MetaCyc:4.2.2.8-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0002528 name: glucuronate-2-sulfatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate." [EC:3.1.6.18] synonym: "chondro-2-sulfatase activity" EXACT [EC:3.1.6.18] synonym: "glucuronate-2-sulphatase activity" EXACT [] synonym: "glucurono-2-sulfatase activity" EXACT [EC:3.1.6.18] synonym: "polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity" EXACT [EC:3.1.6.18] xref: EC:3.1.6.18 xref: GO:0015024 xref: MetaCyc:3.1.6.18-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0002529 name: coreceptor activity namespace: molecular_function def: "Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity." [GOC:go_curators] xref: GO:0015026 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0002530 name: coreceptor, soluble ligand activity namespace: molecular_function xref: GO:0015027 is_a: CCO:F0002529 ! coreceptor activity [Term] id: CCO:F0002531 name: coreceptor, insoluble ligand activity namespace: molecular_function xref: GO:0015028 is_a: CCO:F0002529 ! coreceptor activity [Term] id: CCO:F0002532 name: protein disulfide oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds." [MetaCyc:DISULFOXRED-RXN-] subset: gosubset_prok synonym: "protein disulphide oxidoreductase activity" EXACT [] xref: GO:0015035 xref: MetaCyc:DISULFOXRED-RXN is_a: CCO:F0002533 ! disulfide oxidoreductase activity [Term] id: CCO:F0002533 name: disulfide oxidoreductase activity namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction that interconverts reduced sulfide groups and oxidized disulfide bonds in a substrate." [GOC:mah, MetaCyc:DISULFOXRED-RXN] subset: gosubset_prok synonym: "disulphide oxidoreductase activity" EXACT [] xref: GO:0015036 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0002534 name: peptide disulfide oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds." [GOC:mah, MetaCyc:DISULFOXRED-RXN-] subset: gosubset_prok synonym: "peptide disulphide oxidoreductase activity" EXACT [] xref: GO:0015037 is_a: CCO:F0002533 ! disulfide oxidoreductase activity [Term] id: CCO:F0002535 name: glutathione disulfide oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor." [GOC:mah] subset: gosubset_prok synonym: "glutaredoxin" RELATED [] synonym: "glutathione disulphide oxidoreductase activity" EXACT [] xref: GO:0015038 is_a: CCO:F0002534 ! peptide disulfide oxidoreductase activity [Term] id: CCO:F0002536 name: NADPH-adrenodoxin reductase activity namespace: molecular_function def: "Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+." [EC:1.18.1.2, GOC:kd] comment: Note that this term specifically refers to the reaction proceeding in the direction shown; under physiological conditions adrenodoxin reduction by adrenodoxin reductase is coupled with electron transfer from AdR to P450, which catalyzes an irreversible monooxygenation reaction. This term should therefore be used to annotate gene products that catalyze the reduction of oxidized adrenodoxin; also consider annotating to the molecular function term 'ferredoxin-NADP+ reductase activity ; GO:0004324'. synonym: "adrenodoxin reductase activity" BROAD [EC:1.18.1.2] synonym: "adrenodoxin-type ferredoxin reductase activity" EXACT [GOC:kd] synonym: "NADPH:adrenodoxin oxidoreductase activity" EXACT [EC:1.18.1.2] xref: EC:1.18.1.- xref: GO:0015039 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002537 name: trypanothione-disulfide reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide." [EC:1.8.1.12] comment: Note that this function was formerly EC:1.6.4.8. synonym: "N(1),N(8)-bis(glutathionyl)spermidine reductase activity" EXACT [EC:1.8.1.12] synonym: "N1,N8-bis(glutathionyl)spermidine reductase activity" EXACT [EC:1.8.1.12] synonym: "NADPH2:trypanothione oxidoreductase activity" EXACT [EC:1.8.1.12] synonym: "NADPH:trypanothione oxidoreductase activity" EXACT [EC:1.8.1.12] synonym: "trypanothione reductase activity" EXACT [] synonym: "trypanothione-disulphide reductase activity" EXACT [] synonym: "trypanothione:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.12] xref: EC:1.8.1.12 xref: GO:0015042 xref: MetaCyc:1.8.1.12-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0002538 name: leghemoglobin reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin." [EC:1.6.2.6] synonym: "ferric leghemoglobin reductase activity" EXACT [EC:1.6.2.6] synonym: "NAD(P)H:ferrileghemoglobin oxidoreductase activity" EXACT [EC:1.6.2.6] xref: EC:1.6.2.6 xref: GO:0015043 xref: MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN is_a: CCO:F0003251 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor [Term] id: CCO:F0002539 name: rubredoxin-NAD+ reductase activity namespace: molecular_function def: "Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+." [EC:1.18.1.1] subset: gosubset_prok synonym: "dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity" EXACT [EC:1.18.1.1] synonym: "DPNH-rubredoxin reductase activity" EXACT [EC:1.18.1.1] synonym: "NADH--rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.1] synonym: "NADH--rubredoxin reductase activity" EXACT [EC:1.18.1.1] synonym: "NADH:rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.1] synonym: "NADH:rubredoxin reductase activity" EXACT [] synonym: "reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity" EXACT [EC:1.18.1.1] synonym: "rubredoxin--NAD reductase activity" EXACT [EC:1.18.1.1] synonym: "rubredoxin--nicotinamide adenine dinucleotide reductase activity" EXACT [EC:1.18.1.1] synonym: "rubredoxin:NAD+ oxidoreductase activity" EXACT [EC:1.18.1.1] xref: EC:1.18.1.1 xref: GO:0015044 xref: MetaCyc:RUBREDOXIN--NAD(+)-REDUCTASE-RXN is_a: CCO:F0002541 ! rubredoxin reductase activity [Term] id: CCO:F0002540 name: rubredoxin-NAD(P)+ reductase activity namespace: molecular_function def: "Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+." [EC:1.18.1.4] synonym: "dinucleotide phosphate reductase activity" RELATED [EC:1.18.1.4] synonym: "NAD(P)--rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.4] synonym: "NAD(P)H--rubredoxin oxidoreductase activity" EXACT [EC:1.18.1.4] synonym: "NADPH:rubredoxin reductase activity" EXACT [] synonym: "rubredoxin--nicotinamide adenine activity" RELATED [EC:1.18.1.4] synonym: "rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity" EXACT [EC:1.18.1.4] synonym: "rubredoxin:NAD(P)+ oxidoreductase activity" EXACT [EC:1.18.1.4] xref: EC:1.18.1.4 xref: GO:0015045 xref: MetaCyc:RUBREDOXIN--NADP(+)-REDUCTASE-RXN is_a: CCO:F0002541 ! rubredoxin reductase activity [Term] id: CCO:F0002541 name: rubredoxin reductase activity namespace: molecular_function def: "Catalysis of the reactions: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+." [EC:1.18.1.-] subset: gosubset_prok xref: EC:1.18.1.- xref: GO:0015046 is_a: CCO:F0003312 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor [Term] id: CCO:F0002542 name: NADPH-cytochrome-c2 reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2." [EC:1.6.2.5] synonym: "cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH)" EXACT [EC:1.6.2.5] synonym: "NADPH:ferricytochrome-c2 oxidoreductase activity" EXACT [EC:1.6.2.5] synonym: "reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.6.2.5] xref: EC:1.6.2.5 xref: GO:0015047 xref: MetaCyc:NADPH--CYTOCHROME-C2-REDUCTASE-RXN is_a: CCO:F0003251 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor [Term] id: CCO:F0002543 name: phthalate dioxygenase reductase activity namespace: molecular_function def: "Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems." [PMID:7589982] xref: GO:0015048 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0002544 name: methane monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O." [EC:1.14.13.25] subset: gosubset_prok synonym: "methane hydroxylase activity" EXACT [EC:1.14.13.25] synonym: "methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.13.25] xref: EC:1.14.13.25 xref: GO:0015049 xref: MetaCyc:METHANE-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0007 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0002545 name: X-opioid receptor activity namespace: molecular_function xref: GO:0015051 is_a: CCO:F0001323 ! opioid receptor activity [Term] id: CCO:F0002546 name: beta3-adrenergic receptor activity namespace: molecular_function synonym: "beta3 adrenoceptor" EXACT [] xref: GO:0015052 is_a: CCO:F0001281 ! beta-adrenergic receptor activity [Term] id: CCO:F0002547 name: gastrin receptor activity namespace: molecular_function def: "Combining with gastrin to initiate a change in cell activity." [GOC:ai] synonym: "cholecystokinin-B receptor activity" EXACT [] xref: GO:0015054 is_a: CCO:F0001293 ! cholecystokinin receptor activity [Term] id: CCO:F0002548 name: secretin receptor activity namespace: molecular_function def: "Combining with secretin to initiate a change in cell activity." [GOC:mah] xref: GO:0015055 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0002549 name: corticotrophin-releasing factor receptor activity namespace: molecular_function def: "Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity." [PMID:12032352] xref: GO:0015056 is_a: CCO:F0000186 ! corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity [Term] id: CCO:F0002550 name: thrombin receptor activity namespace: molecular_function def: "Combining with thrombin to initiate a change in cell activity." [GOC:ai] xref: GO:0015057 is_a: CCO:F0000195 ! peptide receptor activity [Term] id: CCO:F0002551 name: epidermal growth factor-like module containing hormone receptor activity namespace: molecular_function synonym: "EGF-like module containing hormone receptor activity" EXACT [] synonym: "Egr1 hormone receptor" EXACT [] xref: GO:0015058 xref: GO:0016523 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0002552 name: uridine nucleotide receptor activity namespace: molecular_function def: "Combining with UTP or UDP to initiate a change in cell activity." [UniProtKB:P51582] synonym: "purinoceptor type U" EXACT [] xref: GO:0015065 is_a: CCO:F0006063 ! purinergic nucleotide receptor activity, G-protein coupled [Term] id: CCO:F0002553 name: alpha-amylase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of alpha-amylase." [GOC:mah] subset: gosubset_prok xref: GO:0015066 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0002554 name: amidinotransferase activity namespace: molecular_function def: "Catalysis of the reversible transfer of an amidino group to an acceptor." [GOC:ai] subset: gosubset_prok synonym: "transamidinase activity" EXACT [] xref: EC:2.1.4.- xref: GO:0015067 is_a: CCO:F0003317 ! transferase activity, transferring one-carbon groups is_a: CCO:F0003342 ! transferase activity, transferring nitrogenous groups [Term] id: CCO:F0002555 name: glycine amidinotransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate." [EC:2.1.4.1] subset: gosubset_prok synonym: "arginine-glycine amidinotransferase activity" EXACT [EC:2.1.4.1] synonym: "arginine-glycine transamidinase activity" EXACT [EC:2.1.4.1] synonym: "glycine transamidinase activity" EXACT [EC:2.1.4.1] synonym: "L-arginine:glycine amidinotransferase activity" EXACT [EC:2.1.4.1] xref: EC:2.1.4.1 xref: GO:0015068 xref: MetaCyc:GLYCINE-AMIDINOTRANSFERASE-RXN xref: Reactome:19902 is_a: CCO:F0002554 ! amidinotransferase activity [Term] id: CCO:F0002556 name: scyllo-inosamine-4-phosphate amidinotransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate = L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate." [EC:2.1.4.2] subset: gosubset_prok synonym: "inosamine-P amidinotransferase activity" EXACT [EC:2.1.4.2] synonym: "inosamine-phosphate amidinotransferase activity" EXACT [] synonym: "L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity" EXACT [EC:2.1.4.2] synonym: "L-arginine:inosamine phosphate amidinotransferase activity" EXACT [EC:2.1.4.2] synonym: "L-arginine:inosamine-P-amidinotransferase activity" EXACT [EC:2.1.4.2] xref: EC:2.1.4.2 xref: GO:0015069 xref: MetaCyc:2.1.4.2-RXN is_a: CCO:F0002554 ! amidinotransferase activity [Term] id: CCO:F0002557 name: ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an ion from one side of a membrane to the other." [GOC:def, GOC:df, GOC:mtg_transport, ISBN:0815340729] subset: goslim_goa subset: gosubset_prok synonym: "ion transporter activity" EXACT [] xref: GO:0015075 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0002558 name: monovalent inorganic cation transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "univalent inorganic cation transporter" EXACT [] xref: GO:0015077 is_a: CCO:F0004309 ! inorganic cation transmembrane transporter activity [Term] id: CCO:F0002559 name: hydrogen ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of hydrogen ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "proton transporter" EXACT [] xref: GO:0015078 xref: Reactome:1383 is_a: CCO:F0002558 ! monovalent inorganic cation transmembrane transporter activity [Term] id: CCO:F0002560 name: potassium ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of potassium ions (K+) from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "potassium transporter" EXACT [] xref: GO:0015079 xref: GO:0022817 is_a: CCO:F0002558 ! monovalent inorganic cation transmembrane transporter activity is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0002561 name: silver ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of silver (Ag) ions from one side of a membrane to the other." [GOC:ai] synonym: "silver transporter" EXACT [] xref: GO:0015080 is_a: CCO:F0002558 ! monovalent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0002562 name: sodium ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "sodium transporter" EXACT [] xref: GO:0015081 xref: GO:0022816 is_a: CCO:F0002558 ! monovalent inorganic cation transmembrane transporter activity is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0002563 name: di-, tri-valent inorganic cation transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of inorganic cations with a valency of two or three from one side of the membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015082 is_a: CCO:F0004309 ! inorganic cation transmembrane transporter activity [Term] id: CCO:F0002564 name: aluminum ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of aluminum (Al) ions from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "aluminium ion transporter activity" EXACT [] synonym: "aluminium resistance permease activity" EXACT [] synonym: "aluminum resistance permease activity" EXACT [] xref: GO:0015083 xref: GO:0015084 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0002565 name: calcium ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of calcium (Ca) ions from one side of a membrane to the other." [GOC:df] subset: gosubset_prok xref: GO:0015085 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0002566 name: cadmium ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cadmium (Cd) ions from one side of a membrane to the other." [GOC:df] subset: gosubset_prok synonym: "zinc, cadmium uptake permease activity" NARROW [] synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" NARROW [] xref: GO:0015086 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0002567 name: cobalt ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cobalt (Co) ions from one side of a membrane to the other." [GOC:df] subset: gosubset_prok synonym: "cobalt, zinc uptake permease activity" NARROW [] synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" NARROW [] xref: GO:0015087 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0002568 name: copper uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu+(out) = Cu+(in)." [TC:9.A.12.-.-] xref: GO:0015088 is_a: CCO:F0001598 ! copper ion transmembrane transporter activity [Term] id: CCO:F0002569 name: high affinity copper ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu2+(out) = Cu2+(in)." [TC:9.A.11.1.1] synonym: "high affinity copper transporter" EXACT [] xref: GO:0015089 is_a: CCO:F0001598 ! copper ion transmembrane transporter activity [Term] id: CCO:F0002570 name: low affinity iron ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in)." [TC:9.A.9.1.1] synonym: "low affinity iron transporter" EXACT [] xref: GO:0015090 is_a: CCO:F0001599 ! iron ion transmembrane transporter activity [Term] id: CCO:F0002571 name: ferric iron transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015091 is_a: CCO:F0001599 ! iron ion transmembrane transporter activity [Term] id: CCO:F0002572 name: high affinity ferric uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of Fe(III) from the outside of a cell to the inside of a cell across a membrane." [GOC:ai, TC:9.A.10.1.1] xref: GO:0015092 is_a: CCO:F0002571 ! ferric iron transmembrane transporter activity [Term] id: CCO:F0002573 name: ferrous iron transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015093 is_a: CCO:F0001599 ! iron ion transmembrane transporter activity [Term] id: CCO:F0002574 name: lead ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of lead (Pb) ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" NARROW [] xref: GO:0015094 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0002575 name: magnesium ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of magnesium (Mg) ions from one side of a membrane to the other." [GOC:df] subset: gosubset_prok xref: GO:0015095 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0002576 name: mercury ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of mercury (Hg) ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015097 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0002577 name: molybdate ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "molybdate transporter activity" EXACT [] xref: GO:0015098 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002578 name: nickel ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nickel (Ni) ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" NARROW [] xref: GO:0015099 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0002579 name: vanadium ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of vanadium (V) ions from one side of a membrane to the other." [GOC:ai] xref: GO:0015100 is_a: CCO:F0002563 ! di-, tri-valent inorganic cation transmembrane transporter activity is_a: CCO:F0006269 ! transition metal ion transmembrane transporter activity [Term] id: CCO:F0002580 name: organic cation transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015101 is_a: CCO:F0001835 ! cation transmembrane transporter activity [Term] id: CCO:F0002581 name: inorganic anion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:ai] subset: gosubset_prok xref: GO:0015103 is_a: CCO:F0001962 ! anion transmembrane transporter activity [Term] id: CCO:F0002582 name: antimonite transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of antimonite from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015104 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002583 name: arsenite transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of arsenite from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015105 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002584 name: bicarbonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] xref: GO:0015106 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002585 name: chlorate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of chlorate from one side of a membrane to the other. Chlorates are inorganic salts of chloric acid that contain the ClO3- ion." [http://cancerweb.ncl.ac.uk/] xref: GO:0015107 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002586 name: chloride transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of chloride ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015108 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002587 name: chromate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3." [GOC:ai] subset: gosubset_prok xref: GO:0015109 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002588 name: cyanate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015110 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002589 name: iodide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of iodide ions from one side of a membrane to the other." [GOC:ai] xref: GO:0015111 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002590 name: nitrate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nitrate ions (NO3-) from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "nitrite/nitrate porter activity" NARROW [] xref: GO:0015112 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002591 name: nitrite transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nitrite (NO2(-)) ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "nitrite/nitrate porter activity" NARROW [] xref: GO:0015113 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002592 name: phosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015114 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002593 name: silicate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates." [GOC:ai, http://cancerweb.ncl.ac.uk/] xref: GO:0015115 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002594 name: sulfate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sulfate ions (SO4 2-) from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "sulfate permease activity" RELATED [] synonym: "sulphate transporter activity" EXACT [] xref: GO:0015116 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002595 name: thiosulfate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of thiosulfate ions (S2O3 2-) from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "thiosulfate permease activity" RELATED [] synonym: "thiosulphate transporter activity" EXACT [] xref: GO:0015117 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002596 name: tellurite transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals." [GOC:ai, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok xref: GO:0015118 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0002597 name: hexose phosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of hexose phosphate from one side of the membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015119 is_a: CCO:F0002622 ! monosaccharide transmembrane transporter activity [Term] id: CCO:F0002598 name: phosphoglycerate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of phosphoglycerates from one side of the membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis." [GOC:ai] subset: gosubset_prok xref: GO:0015120 is_a: CCO:F0001570 ! organic acid transmembrane transporter activity is_a: CCO:F0001967 ! organic anion transmembrane transporter activity [Term] id: CCO:F0002599 name: phosphoenolpyruvate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of phosphoenolpyruvate from one side of a membrane to the other. Phosphoenolpyruvate is the phosphate ester formed from the hydroxy group of the enol tautomer of pyruvate. It is a key intermediate in glycolysis and gluconeogenesis, and in the biosynthesis of aromatic amino acids." [GOC:ai] xref: GO:0015121 is_a: CCO:F0001967 ! organic anion transmembrane transporter activity [Term] id: CCO:F0002600 name: acetate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of acetate from one side of the membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai] xref: GO:0015123 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002601 name: allantoate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of allantoate from one side of the membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen." [GOC:ai, ISBN:0198547684] xref: GO:0015124 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002602 name: bile acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of bile acid from one side of the membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:ai] xref: GO:0015125 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002603 name: canalicular bile acid transmembrane transporter activity namespace: molecular_function xref: GO:0015126 is_a: CCO:F0002602 ! bile acid transmembrane transporter activity [Term] id: CCO:F0002604 name: bilirubin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of bilirubin from one side of the membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684] xref: GO:0015127 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002605 name: gluconate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of gluconate from one side of the membrane to the other. Gluconate is the aldonic acid derived from glucose." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "L-idonate/D-gluconate:hydrogen symporter activity" NARROW [] xref: GO:0015128 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002606 name: lactate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of lactate from one side of the membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" NARROW [] xref: GO:0015129 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002607 name: mevalonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of mevalonate from one side of the membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" NARROW [] xref: GO:0015130 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002608 name: oxaloacetate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of the membrane to the other." [GOC:ai] xref: GO:0015131 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002609 name: prostaglandin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of prostaglandins from one side of the membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities." [GOC:ai] synonym: "prostaglandin/thromboxane transporter activity" BROAD [] xref: GO:0015132 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002610 name: uronic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of uronic acid from one side of the membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose." [GOC:ai] subset: gosubset_prok xref: GO:0015133 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002611 name: hexuronate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of hexuronates from one side of the membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015134 is_a: CCO:F0002610 ! uronic acid transmembrane transporter activity [Term] id: CCO:F0002612 name: glucuronate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glucuronate from one side of the membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:ai] xref: GO:0015135 is_a: CCO:F0002611 ! hexuronate transmembrane transporter activity [Term] id: CCO:F0002613 name: sialic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sialic acid from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015136 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0002614 name: citrate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of the membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015137 is_a: CCO:F0002619 ! tricarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002615 name: fumarate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of fumarate from one side of the membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate." [GOC:ai] synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" NARROW [] xref: GO:0015138 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002616 name: alpha-ketoglutarate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of alpha-ketoglutarate from one side of the membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle." [GOC:ai, ISBN:0198547684] subset: gosubset_prok synonym: "2-oxoglutarate transporter" EXACT [] xref: GO:0015139 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002617 name: malate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of malate from one side of the membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle." [GOC:ai] synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" NARROW [] xref: GO:0015140 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002618 name: succinate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of the membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" NARROW [] xref: GO:0015141 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002619 name: tricarboxylic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of tricarboxylic acids from one side of the membrane to the other. Tricarboxylic acid are organic acids with three COOH groups." [GOC:ai] subset: gosubset_prok synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] xref: GO:0015142 is_a: CCO:F0006282 ! carboxylic acid transmembrane transporter activity [Term] id: CCO:F0002620 name: urate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of urate from one side of the membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals." [GOC:ai] synonym: "uric acid transmembrane transporter activity" EXACT [] xref: GO:0015143 is_a: CCO:F0001570 ! organic acid transmembrane transporter activity [Term] id: CCO:F0002621 name: carbohydrate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of carbohydrate from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "sugar transporter" NARROW [] xref: GO:0015144 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0002622 name: monosaccharide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of monosaccharide from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015145 is_a: CCO:F0008062 ! sugar transmembrane transporter activity [Term] id: CCO:F0002623 name: pentose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a pentose sugar, a monosaccharide with 5 carbon atoms, from one side of the membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015146 is_a: CCO:F0002622 ! monosaccharide transmembrane transporter activity [Term] id: CCO:F0002624 name: L-arabinose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-arabinose from one side of the membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity" NARROW [] xref: GO:0015147 is_a: CCO:F0005736 ! arabinose transmembrane transporter activity [Term] id: CCO:F0002625 name: D-xylose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-xylose from one side of the membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok xref: GO:0015148 is_a: CCO:F0002623 ! pentose transmembrane transporter activity [Term] id: CCO:F0002626 name: hexose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of the membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015149 is_a: CCO:F0002622 ! monosaccharide transmembrane transporter activity [Term] id: CCO:F0002627 name: fucose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of fucose from one side of the membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015150 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002628 name: alpha-glucoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of alpha-glucosides from one side of the membrane to the other. Alpha-glucosides are glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration." [GOC:jl, GOC:mtg_transport, http://www.biochem.purdue.edu/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] xref: GO:0015151 is_a: CCO:F0005760 ! glucoside transmembrane transporter activity [Term] id: CCO:F0002629 name: glucose-6-phosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glucose-6-phosphate from one side of the membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0015152 is_a: CCO:F0002597 ! hexose phosphate transmembrane transporter activity [Term] id: CCO:F0002630 name: rhamnose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of rhamnose from one side of the membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015153 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002631 name: disaccharide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of disaccharide from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015154 is_a: CCO:F0008062 ! sugar transmembrane transporter activity [Term] id: CCO:F0002632 name: lactose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of lactose from one side of the membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "lactose permease activity" EXACT [] synonym: "lactose/glucose efflux transporter activity" NARROW [] xref: GO:0015155 xref: GO:0019189 is_a: CCO:F0002631 ! disaccharide transmembrane transporter activity [Term] id: CCO:F0002633 name: melibiose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of melibiose from one side of the membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok xref: GO:0015156 is_a: CCO:F0002631 ! disaccharide transmembrane transporter activity [Term] id: CCO:F0002634 name: oligosaccharide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of oligosaccharide from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "endosomal oligosaccharide transporter" NARROW [] xref: GO:0015157 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0002635 name: raffinose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of raffinose from one side of the membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "raffinose permease" RELATED [] xref: GO:0015158 is_a: CCO:F0002634 ! oligosaccharide transmembrane transporter activity [Term] id: CCO:F0002636 name: polysaccharide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of polysaccharides from one side of the membrane to the other. A polysaccharide is a polymer of more than about 10 monosaccharide residues joined by glycosidic linkages." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015159 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0002637 name: beta-glucan transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of beta-glucans from one side of the membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0015160 is_a: CCO:F0002636 ! polysaccharide transmembrane transporter activity [Term] id: CCO:F0002638 name: capsular-polysaccharide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of capsular-polysaccharides from one side of the membrane to the other. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "capsule polysaccharide transporter activity" EXACT [] xref: GO:0015161 is_a: CCO:F0002636 ! polysaccharide transmembrane transporter activity [Term] id: CCO:F0002639 name: teichoic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of teichoic acid from one side of the membrane to the other. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015162 is_a: CCO:F0002636 ! polysaccharide transmembrane transporter activity [Term] id: CCO:F0002640 name: hexuronide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a hexuronide from one side of the membrane to the other. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015163 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0002641 name: glucuronoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a glucuronosides from one side of the membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "glucuronide transporter activity" EXACT [] xref: GO:0015164 is_a: CCO:F0002640 ! hexuronide transmembrane transporter activity [Term] id: CCO:F0002642 name: pyrimidine nucleotide sugar transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a pyrimidine nucleotide-sugar from one side of the membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0015165 is_a: CCO:F0001568 ! nucleotide-sugar transmembrane transporter activity [Term] id: CCO:F0002643 name: polyol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a polyol from one side of the membrane to the other. A polyol is any polyhydric alcohol." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "sugar/polyol channel activity" NARROW [] xref: GO:0015166 is_a: CCO:F0003013 ! alcohol transmembrane transporter activity [Term] id: CCO:F0002644 name: arabitol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an arabitol from one side of the membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "arabinitol transporter activity" EXACT [] xref: GO:0015167 is_a: CCO:F0002643 ! polyol transmembrane transporter activity [Term] id: CCO:F0002645 name: glycerol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glycerol from one side of the membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids." [GOC:ai] subset: gosubset_prok xref: GO:0015168 is_a: CCO:F0002643 ! polyol transmembrane transporter activity [Term] id: CCO:F0002646 name: glycerol-3-phosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glycerol-3-phosphate from one side of the membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol." [GOC:ai] subset: gosubset_prok xref: GO:0015169 is_a: CCO:F0002645 ! glycerol transmembrane transporter activity [Term] id: CCO:F0002647 name: propanediol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of propanediol from one side of the membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects." [GOC:ai] xref: GO:0015170 is_a: CCO:F0002643 ! polyol transmembrane transporter activity [Term] id: CCO:F0002648 name: amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "amino acid permease activity" EXACT [] synonym: "amino acid transporter activity" BROAD [] synonym: "amino acid/choline transmembrane transporter activity" NARROW [] synonym: "general amino acid permease activity" RELATED [] synonym: "hydroxy/aromatic amino acid permease activity" NARROW [] xref: GO:0015171 xref: GO:0015359 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0006282 ! carboxylic acid transmembrane transporter activity [Term] id: CCO:F0002649 name: acidic amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have a pH below 7." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "acidic amino acid transporter activity" BROAD [] xref: GO:0015172 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0002650 name: aromatic amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "aromatic amino acid transporter activity" BROAD [] synonym: "hydroxy/aromatic amino acid permease activity" NARROW [] synonym: "valine/tyrosine/tryptophan permease activity" RELATED [] xref: GO:0015173 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0002651 name: basic amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "basic amino acid permease activity" EXACT [] synonym: "basic amino acid transporter activity" BROAD [] xref: GO:0005286 xref: GO:0015174 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0002652 name: neutral amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "neutral amino acid transporter activity" BROAD [] xref: GO:0015175 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0002653 name: L-amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the levorotatory isomer of amino acids." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-amino acid transporter activity" BROAD [] xref: GO:0015179 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0002654 name: L-alanine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-alanine from one side of a membrane to the other. L-alanine, the levorotatory isomer of 2-aminopropanoic acid." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "L-alanine transporter activity" BROAD [] xref: GO:0015180 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity is_a: CCO:F0004285 ! alanine transmembrane transporter activity [Term] id: CCO:F0002655 name: arginine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "arginine permease activity" EXACT [] synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] synonym: "L-arginine transporter activity" NARROW [] xref: GO:0005288 xref: GO:0015181 is_a: CCO:F0002651 ! basic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002656 name: L-asparagine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the levorotatory isomer of alpha-aminosuccinamic acid." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "asparagine/glutamine permease activity" NARROW [] synonym: "L-asparagine transporter activity" BROAD [] xref: GO:0015182 is_a: CCO:F0002651 ! basic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002657 name: L-aspartate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "glutamate/aspartate porter activity" NARROW [] synonym: "glutamate/aspartate:sodium symporter activity" NARROW [] synonym: "L-aspartate transporter activity" BROAD [] xref: GO:0015183 is_a: CCO:F0002649 ! acidic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002658 name: L-cystine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-cystine from one side of a membrane to the other." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] synonym: "cystine/diaminopimelate porter activity" NARROW [] synonym: "L-cystine transporter activity" BROAD [] xref: GO:0015184 is_a: CCO:F0000019 ! sulfur amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002659 name: L-gamma-aminobutyric acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-gamma-aminobutyric acid from one side of a membrane to the other. L-gamma-aminobutyric acid is 4-aminobutyrate (GABA)." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "4-aminobutanoate transporter activity" EXACT [] synonym: "4-aminobutyrate transporter activity" EXACT [] synonym: "betaine/GABA:sodium symporter activity" NARROW [] synonym: "GABA transporter activity" EXACT [] synonym: "L-gamma-aminobutyrate transporter activity" EXACT [] synonym: "L-gamma-aminobutyric acid transporter activity" BROAD [] xref: GO:0015185 is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002660 name: L-glutamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "asparagine/glutamine permease activity" NARROW [] xref: GO:0015186 is_a: CCO:F0002651 ! basic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002661 name: glycine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid." [GOC:ai] subset: gosubset_prok synonym: "glycine betaine/proline porter activity" NARROW [] synonym: "glycine transporter activity" BROAD [] synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] xref: GO:0015187 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity [Term] id: CCO:F0002662 name: L-isoleucine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "isoleucine/valine:sodium symporter activity" NARROW [] synonym: "L-isoleucine transporter activity" BROAD [] synonym: "leucine/isoleucine/valine porter activity" NARROW [] synonym: "leucine/valine/isoleucine permease activity" NARROW [] xref: GO:0015188 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002663 name: L-lysine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "histidine/arginine/lysine/ornithine porter activity" NARROW [] synonym: "L-lysine permease" RELATED [] synonym: "lysine permease activity" RELATED [] xref: GO:0005293 xref: GO:0015189 is_a: CCO:F0002651 ! basic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002664 name: L-leucine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "L-leucine transporter activity" BROAD [] synonym: "leucine/isoleucine/valine porter activity" NARROW [] synonym: "leucine/valine/isoleucine permease activity" NARROW [] xref: GO:0015190 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002665 name: L-methionine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-methionine transporter activity" BROAD [] xref: GO:0015191 is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity is_a: CCO:F0006027 ! methionine transmembrane transporter activity [Term] id: CCO:F0002666 name: L-phenylalanine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-phenylalanine permease activity" EXACT [] synonym: "L-phenylalanine transporter activity" BROAD [] xref: GO:0015192 is_a: CCO:F0002650 ! aromatic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002667 name: L-proline transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "glycine betaine/proline porter activity" NARROW [] synonym: "L-proline permease activity" RELATED [] synonym: "L-proline transporter activity" BROAD [] synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] xref: GO:0005296 xref: GO:0015193 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002668 name: L-serine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-serine from one side of a membrane to the other. L-serine is the levorotatory isomer of 2-amino-3-hydroxypropanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-serine permease activity" RELATED [] synonym: "L-serine transporter activity" BROAD [] synonym: "serine transporter activity" BROAD [] synonym: "threonine/serine:sodium symporter activity" NARROW [] xref: GO:0015194 xref: GO:0015511 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity is_a: CCO:F0004308 ! serine transmembrane transporter activity [Term] id: CCO:F0002669 name: L-threonine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-threonine permease activity" RELATED [] synonym: "L-threonine transporter activity" BROAD [] synonym: "threonine/serine:sodium symporter activity" NARROW [] xref: GO:0015195 xref: GO:0015512 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002670 name: L-tryptophan transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-tryptophan permease activity" EXACT [] synonym: "L-tryptophan transporter activity" BROAD [] synonym: "valine/tyrosine/tryptophan permease activity" NARROW [] xref: GO:0005299 xref: GO:0015196 is_a: CCO:F0002650 ! aromatic amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002671 name: peptide transporter activity namespace: molecular_function def: "Enables the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of, within or between cells." [GOC:ai] subset: gosubset_prok synonym: "peptide uptake permease activity" RELATED [] xref: GO:0015197 xref: GO:0015637 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0002672 name: oligopeptide transporter activity namespace: molecular_function def: "Enables the directed movement of oligopeptides into, out of, within or between cells. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015198 is_a: CCO:F0002671 ! peptide transporter activity [Term] id: CCO:F0002673 name: betaine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of betaine, the N-trimethyl derivative of an amino acid, from one side of the membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "betaine/GABA:sodium symporter activity" NARROW [] synonym: "glycine betaine/proline porter activity" NARROW [] synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] xref: GO:0015199 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0002674 name: methylammonium transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of methylammonium, CH3NH2, into, out of, within or between cells." [GOC:ai] xref: GO:0015200 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0002675 name: polyamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of polyamines, organic compounds containing two or more amino groups, from one side of the membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "amine/amide/polyamine channel activity" NARROW [] xref: GO:0015203 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0002676 name: urea transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of urea cross a membrane into, out of, within or between cells. Urea is the water soluble compound H2N-CO-NH2, produced in the liver via the ornithine-urea cycle. It is the main nitrogen-containing (urinary) excretion product in ureotelic animals." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "urea transporter activity" BROAD [] xref: GO:0015204 xref: GO:0015287 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0005729 ! amide transporter activity [Term] id: CCO:F0002677 name: nucleobase transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015205 xref: GO:0015392 is_a: CCO:F0003026 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity [Term] id: CCO:F0002678 name: adenine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of adenine, 6-aminopurine, from one side of a membrane to the other." [GOC:go_curators] xref: GO:0015207 xref: Reactome:21842 is_a: CCO:F0001573 ! purine transmembrane transporter activity [Term] id: CCO:F0002679 name: guanine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other." [GOC:go_curators] xref: GO:0015208 is_a: CCO:F0001573 ! purine transmembrane transporter activity [Term] id: CCO:F0002680 name: cytosine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other." [GOC:go_curators] subset: gosubset_prok xref: GO:0015209 is_a: CCO:F0001576 ! pyrimidine transmembrane transporter activity [Term] id: CCO:F0002681 name: uracil transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other." [GOC:go_curators] subset: gosubset_prok synonym: "uracil/uridine permease activity" RELATED [] xref: GO:0015210 is_a: CCO:F0001576 ! pyrimidine transmembrane transporter activity [Term] id: CCO:F0002682 name: purine nucleoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015211 is_a: CCO:F0001567 ! nucleoside transmembrane transporter activity [Term] id: CCO:F0002683 name: cytidine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cytidine, cytosine riboside, from one side of a membrane to the other." [GOC:go_curators] xref: GO:0015212 is_a: CCO:F0002685 ! pyrimidine nucleoside transmembrane transporter activity [Term] id: CCO:F0002684 name: uridine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of uridine, uracil riboside, from one side of a membrane to the other." [GOC:go_curators] synonym: "uracil/uridine permease activity" NARROW [] xref: GO:0015213 is_a: CCO:F0002685 ! pyrimidine nucleoside transmembrane transporter activity [Term] id: CCO:F0002685 name: pyrimidine nucleoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other." [GOC:ai] xref: GO:0015214 is_a: CCO:F0001567 ! nucleoside transmembrane transporter activity [Term] id: CCO:F0002686 name: nucleotide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015215 is_a: CCO:F0003026 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity [Term] id: CCO:F0002687 name: purine nucleotide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other." [GOC:ai] xref: GO:0015216 is_a: CCO:F0002686 ! nucleotide transmembrane transporter activity [Term] id: CCO:F0002688 name: ADP transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other." [GOC:ai] xref: GO:0015217 is_a: CCO:F0000061 ! adenine nucleotide transmembrane transporter activity [Term] id: CCO:F0002689 name: pyrimidine nucleotide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other." [GOC:ai] xref: GO:0015218 is_a: CCO:F0002686 ! nucleotide transmembrane transporter activity [Term] id: CCO:F0002690 name: DNA-protein complex transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of DNA-protein complexes from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015219 is_a: CCO:F0003026 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity [Term] id: CCO:F0002691 name: choline transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of choline from one side of the membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine." [GOC:ai] subset: gosubset_prok synonym: "amino acid/choline transmembrane transporter activity" NARROW [] synonym: "choline permease activity" EXACT [] xref: GO:0005306 xref: GO:0015220 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0002692 name: lipopolysaccharide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of lipopolysaccharides from one side of the membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "LPS transmembrane transporter activity" EXACT [] xref: GO:0015221 is_a: CCO:F0002636 ! polysaccharide transmembrane transporter activity [Term] id: CCO:F0002693 name: serotonin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of serotonin from one side of the membrane to the other. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] xref: GO:0015222 is_a: CCO:F0001559 ! neurotransmitter transporter activity is_a: CCO:F0001958 ! monoamine transmembrane transporter activity [Term] id: CCO:F0002694 name: biopterin transporter activity namespace: molecular_function def: "Enables the directed movement of biopterin into, out of, within or between cells. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0015224 is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0002695 name: biotin transporter activity namespace: molecular_function def: "Enables the directed movement of biotin into, out of, within or between cells. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions." [GOC:ai] synonym: "vitamin B7 transporter activity" EXACT [] synonym: "vitamin H transporter activity" EXACT [] xref: GO:0015225 is_a: CCO:F0008065 ! vitamin transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0002696 name: carnitine transporter activity namespace: molecular_function def: "Enables the directed movement of carnitine into, out of, within or between cells. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane." [GOC:ai] subset: gosubset_prok synonym: "vitamin Bt transporter activity" EXACT [] xref: GO:0015226 is_a: CCO:F0008065 ! vitamin transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0002697 name: acyl carnitine transporter activity namespace: molecular_function def: "Enables the directed movement of acyl carnitine into, out of, within or between cells. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane." [GOC:ai, http://cancerweb.ncl.ac.uk/] synonym: "acylcarnitine transporter activity" EXACT [] xref: GO:0015227 is_a: CCO:F0002696 ! carnitine transporter activity [Term] id: CCO:F0002698 name: coenzyme A transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of coenzyme A across a membrane into, out of, within or between cells. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester." [GOC:ai] synonym: "coenzyme A transporter activity" BROAD [] xref: GO:0015228 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0008067 ! coenzyme transporter activity [Term] id: CCO:F0002699 name: L-ascorbic acid transporter activity namespace: molecular_function def: "Enables the directed movement of L-ascorbate into, out of, within or between cells. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species." [ChEBI:38290, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "L-ascorbate transporter activity" EXACT [] synonym: "vitamin C transporter activity" EXACT [] xref: GO:0015229 is_a: CCO:F0008065 ! vitamin transporter activity [Term] id: CCO:F0002700 name: FAD transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of flavin-adenine dinucleotide (FAD) across a membrane into, out of, within or between cells. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "FAD transporter activity" BROAD [] synonym: "flavin adenine dinucleotide transmembrane transporter activity" EXACT [] synonym: "flavin-adenine dinucleotide transmembrane transporter activity" EXACT [] xref: GO:0015230 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0002701 name: 5-formyltetrahydrofolate transporter activity namespace: molecular_function def: "Enables the directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells." [GOC:ai] xref: GO:0015231 is_a: CCO:F0001970 ! folic acid transporter activity [Term] id: CCO:F0002702 name: heme transporter activity namespace: molecular_function def: "Enables the directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of, within or between cells." [GOC:ai] subset: gosubset_prok synonym: "haem transporter activity" EXACT [] xref: GO:0015232 is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0002703 name: pantothenate transporter activity namespace: molecular_function def: "Enables the directed movement of pantothenate into, out of, within or between cells. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods." [GOC:ai, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok synonym: "vitamin B5 transporter activity" EXACT [] xref: GO:0015233 is_a: CCO:F0008065 ! vitamin transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0002704 name: thiamin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of thiamin from one side of the membrane to the other. Thiamin is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "thiamin permease activity" EXACT [] synonym: "thiamine permease activity" EXACT [] synonym: "thiamine transmembrane transporter activity" EXACT [] synonym: "vitamin B1 transporter activity" EXACT [] xref: GO:0015234 xref: GO:0015402 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0008065 ! vitamin transporter activity [Term] id: CCO:F0002705 name: cobalamin transporter activity namespace: molecular_function def: "Enables the directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell." [GOC:ai] subset: gosubset_prok synonym: "vitamin B12 transporter activity" EXACT [] xref: GO:0015235 is_a: CCO:F0008065 ! vitamin transporter activity [Term] id: CCO:F0002706 name: drug transporter activity namespace: molecular_function def: "Enables the directed movement of a drug into, out of, within or between cells. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015238 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0002707 name: multidrug transporter activity namespace: molecular_function def: "Enables the directed movement of drugs into, out of, within or between cells." [GOC:ai] subset: gosubset_prok xref: GO:0015239 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0002708 name: amiloride transporter activity namespace: molecular_function def: "Enables the directed movement of amiloride of amiloride into, out of, within or between cells. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0015240 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0002709 name: aminotriazole transporter activity namespace: molecular_function def: "Enables the directed movement of aminotriazole into, out of, within or between cells. Aminotriazole is an effective weed killer that also possesses some antithyroid activity." [http://cancerweb.ncl.ac.uk/] xref: GO:0015241 is_a: CCO:F0006070 ! azole transporter activity [Term] id: CCO:F0002710 name: benomyl transporter activity namespace: molecular_function def: "Enables the directed movement of benomyl into, out of, within or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit." [http://cancerweb.ncl.ac.uk/] xref: GO:0015242 is_a: CCO:F0002706 ! drug transporter activity is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0002711 name: cycloheximide transporter activity namespace: molecular_function def: "Enables the directed movement of cycloheximide into, out of, within or between cells. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0015243 is_a: CCO:F0005732 ! antibiotic transporter activity [Term] id: CCO:F0002712 name: fluconazole transporter activity namespace: molecular_function def: "Enables the directed movement of fluconazole into, out of, within or between cells. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections." [http://cancerweb.ncl.ac.uk/] xref: GO:0015244 is_a: CCO:F0006070 ! azole transporter activity [Term] id: CCO:F0002713 name: fatty acid transporter activity namespace: molecular_function def: "Enables the directed movement of fatty acids into, out of, within or between cells. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015245 is_a: CCO:F0001556 ! lipid transporter activity [Term] id: CCO:F0002714 name: fatty acyl transporter activity namespace: molecular_function def: "Enables the directed movement of a fatty acyl group into, out of, within or between cells. A fatty acyl group is any acyl group derived from a fatty acid." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "peroxisomal fatty acyl transporter" NARROW [] xref: GO:0015246 is_a: CCO:F0001556 ! lipid transporter activity [Term] id: CCO:F0002715 name: aminophospholipid transporter activity namespace: molecular_function def: "Enables the directed movement of aminophospholipids into, out of, within or between cells. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group." [GOC:ai] subset: gosubset_prok xref: GO:0015247 is_a: CCO:F0001671 ! phospholipid transporter activity [Term] id: CCO:F0002716 name: sterol transporter activity namespace: molecular_function def: "Enables the directed movement of sterols into, out of, within or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule." [GOC:ai] xref: GO:0015248 is_a: CCO:F0001556 ! lipid transporter activity [Term] id: CCO:F0002717 name: water channel activity namespace: molecular_function def: "Transport systems of this type catalyze facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "aquaporin" NARROW [] xref: GO:0015250 is_a: CCO:F0001597 ! water transporter activity is_a: CCO:F0004269 ! substrate specific channel activity [Term] id: CCO:F0002718 name: ammonium channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0015251 is_a: CCO:F0001524 ! cation channel activity is_a: CCO:F0001972 ! ammonium transmembrane transporter activity [Term] id: CCO:F0002719 name: hydrogen ion channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0015252 is_a: CCO:F0001524 ! cation channel activity [Term] id: CCO:F0002720 name: glycerol channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of an glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0015254 is_a: CCO:F0002645 ! glycerol transmembrane transporter activity [Term] id: CCO:F0002721 name: propanediol channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport] xref: GO:0015255 is_a: CCO:F0002647 ! propanediol transmembrane transporter activity [Term] id: CCO:F0002722 name: methylammonium channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of an methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2." [GOC:mtg_transport] xref: GO:0015264 is_a: CCO:F0002674 ! methylammonium transmembrane transporter activity [Term] id: CCO:F0002723 name: urea channel activity namespace: molecular_function def: "Catalysis of facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." [GOC:mtg_transport] xref: GO:0015265 is_a: CCO:F0002676 ! urea transmembrane transporter activity is_a: CCO:F0004269 ! substrate specific channel activity [Term] id: CCO:F0002724 name: protein channel activity namespace: molecular_function xref: GO:0015266 is_a: CCO:F0001832 ! protein transmembrane transporter activity is_a: CCO:F0002725 ! channel activity [Term] id: CCO:F0002725 name: channel activity namespace: molecular_function def: "Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules." [GOC:mtg_transport, ISBN:0815340729, TC:1.-.-.-.-] subset: goslim_goa subset: gosubset_prok synonym: "alpha-type channel activity" RELATED [] synonym: "channel-forming toxin activity" RELATED [] synonym: "channel/pore class transporter activity" EXACT [] synonym: "nonselective channel activity" EXACT [] synonym: "pore activity" BROAD [] synonym: "pore class transporter activity" RELATED [] xref: GO:0015249 xref: GO:0015267 xref: GO:0015268 xref: TC:1 is_a: CCO:F0004250 ! passive transmembrane transporter activity [Term] id: CCO:F0002726 name: calcium-activated potassium channel activity namespace: molecular_function def: "Catalysis of the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient." [GOC:dph, GOC:mtg_transport] subset: gosubset_prok xref: GO:0015269 is_a: CCO:F0001502 ! calcium activated cation channel activity is_a: CCO:F0001526 ! potassium channel activity is_a: CCO:F0004270 ! ion gated channel activity [Term] id: CCO:F0002727 name: dihydropyridine-sensitive calcium channel activity namespace: molecular_function xref: GO:0015270 is_a: CCO:F0001513 ! voltage-gated calcium channel activity [Term] id: CCO:F0002728 name: outward rectifier potassium channel activity namespace: molecular_function xref: GO:0015271 is_a: CCO:F0001517 ! voltage-gated potassium channel activity [Term] id: CCO:F0002729 name: ATP-activated inward rectifier potassium channel activity namespace: molecular_function xref: GO:0015272 is_a: CCO:F0001510 ! inward rectifier potassium channel activity [Term] id: CCO:F0002730 name: G-protein enhanced inward rectifier potassium channel activity namespace: molecular_function synonym: "G protein enhanced inward rectifier potassium channel activity" EXACT [] synonym: "G-protein-enhanced inward rectifier potassium channel activity" EXACT [] xref: GO:0015273 is_a: CCO:F0001510 ! inward rectifier potassium channel activity [Term] id: CCO:F0002731 name: organellar voltage-gated chloride channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "organellar voltage gated chloride channel activity" EXACT [] synonym: "organellar voltage-dependent chloride channel activity" EXACT [] xref: GO:0015274 is_a: CCO:F0001515 ! voltage-gated chloride channel activity [Term] id: CCO:F0002732 name: stretch-activated, cation-selective, calcium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching." [GOC:mtg_transport] xref: GO:0015275 is_a: CCO:F0001525 ! calcium channel activity is_a: CCO:F0001855 ! mechanically-gated ion channel activity [Term] id: CCO:F0002733 name: ligand-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "ionotropic neurotransmitter receptor" NARROW [] xref: GO:0015276 is_a: CCO:F0001492 ! ion channel activity is_a: CCO:F0004266 ! ligand-gated channel activity [Term] id: CCO:F0002734 name: kainate selective glutamate receptor activity namespace: molecular_function comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'inotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'. xref: GO:0015277 is_a: CCO:F0001311 ! ionotropic glutamate receptor activity [Term] id: CCO:F0002735 name: calcium-release channel activity namespace: molecular_function xref: GO:0015278 is_a: CCO:F0001525 ! calcium channel activity is_a: CCO:F0002733 ! ligand-gated ion channel activity [Term] id: CCO:F0002736 name: store-operated calcium channel activity namespace: molecular_function xref: GO:0015279 is_a: CCO:F0001525 ! calcium channel activity is_a: CCO:F0002733 ! ligand-gated ion channel activity [Term] id: CCO:F0002737 name: amiloride-sensitive sodium channel activity namespace: molecular_function synonym: "epithelial sodium channel" EXACT [] xref: GO:0015280 is_a: CCO:F0001527 ! sodium channel activity is_a: CCO:F0002733 ! ligand-gated ion channel activity [Term] id: CCO:F0002738 name: fructose uniporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in)." [TC:2.A.1.1.13] xref: GO:0015284 is_a: CCO:F0001579 ! fructose transmembrane transporter activity is_a: CCO:F0001969 ! hexose uniporter activity [Term] id: CCO:F0002739 name: porin activity namespace: molecular_function def: "Catalysis of the transfer of substances, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820, TC:1.B.1.-.-] subset: gosubset_prok synonym: "outer membrane exporter porin" NARROW [] synonym: "porin" EXACT [] xref: GO:0015288 is_a: CCO:F0004262 ! wide pore channel activity [Term] id: CCO:F0002740 name: secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729, PMID:10839820] subset: gosubset_prok synonym: "active transporter" BROAD [] synonym: "coupled carrier" EXACT [] synonym: "electrochemical potential-driven transporter activity" EXACT [] synonym: "galactose/glucose (methylgalactoside) porter activity" NARROW [] synonym: "heavy metal ion porter activity" NARROW [] synonym: "nitrite/nitrate porter activity" NARROW [] synonym: "porter activity" EXACT [] synonym: "porters" EXACT [] synonym: "secondary carrier-type facilitators" EXACT [] xref: GO:0015290 xref: GO:0015291 xref: TC:2.A is_a: CCO:F0004251 ! active transmembrane transporter activity [Term] id: CCO:F0002741 name: uniporter activity namespace: molecular_function def: "Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820] subset: gosubset_prok synonym: "facilitated diffusion carrier" EXACT [] synonym: "single-species transporter" EXACT [] synonym: "uniport" RELATED [] xref: GO:0015292 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002742 name: symporter activity namespace: molecular_function def: "Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820] subset: gosubset_prok synonym: "cotransporter" BROAD [] synonym: "porter" BROAD [] synonym: "symport" RELATED [] xref: GO:0015293 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002743 name: solute:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in)." [GOC:ai] subset: gosubset_prok xref: GO:0015294 is_a: CCO:F0001835 ! cation transmembrane transporter activity is_a: CCO:F0002742 ! symporter activity [Term] id: CCO:F0002744 name: solute:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in)." [GOC:ai] subset: gosubset_prok synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] synonym: "high affinity metal ion uptake transporter activity" NARROW [] synonym: "L-idonate/D-gluconate:hydrogen symporter activity" NARROW [] synonym: "low affinity metal ion uptake transporter activity" NARROW [] synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] synonym: "solute:proton symporter" EXACT [] xref: GO:0015295 is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0002745 name: anion:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in)." [TC:2.A.1.14.-] subset: gosubset_prok xref: GO:0015296 is_a: CCO:F0001962 ! anion transmembrane transporter activity is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0002746 name: antiporter activity namespace: molecular_function def: "Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport, ISBN:0815340729, PMID:10839820] subset: gosubset_prok synonym: "antiport" RELATED [] synonym: "countertransporter" EXACT [] synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" NARROW [] synonym: "exchange transporter" EXACT [] synonym: "exchanger" BROAD [] synonym: "porter" BROAD [] xref: GO:0015297 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002747 name: solute:cation antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out)." [GOC:ai] subset: gosubset_prok xref: GO:0015298 is_a: CCO:F0001835 ! cation transmembrane transporter activity is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0002748 name: solute:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out)." [GOC:ai] subset: gosubset_prok synonym: "L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity" NARROW [] synonym: "solute:proton antiporter" EXACT [] xref: GO:0015299 is_a: CCO:F0002747 ! solute:cation antiporter activity [Term] id: CCO:F0002749 name: solute:solute antiporter activity namespace: molecular_function def: "Catalysis of the reaction: solute A(out) + solute B(in) = solute A(in) + solute B(out)." [GOC:ai] subset: gosubset_prok synonym: "solute:solute exchange" RELATED [] xref: GO:0015300 is_a: CCO:F0002746 ! antiporter activity [Term] id: CCO:F0002750 name: anion:anion antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out)." [GOC:ai, GOC:mtg_transport] subset: gosubset_prok xref: GO:0015301 is_a: CCO:F0001962 ! anion transmembrane transporter activity is_a: CCO:F0002746 ! antiporter activity [Term] id: CCO:F0002751 name: glucose uniporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in)." [TC:2.A.1.1.12, TC:2.A.1.1.4, TC:2.A.1.1.6] synonym: "galactose, glucose uniporter activity" NARROW [] xref: GO:0015304 is_a: CCO:F0001581 ! glucose transmembrane transporter activity is_a: CCO:F0001969 ! hexose uniporter activity [Term] id: CCO:F0002752 name: sialate:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in)." [TC:2.A.1.14.10] synonym: "cation/sialate symporter activity" EXACT [] synonym: "cation:sialate symporter activity" EXACT [] synonym: "sialate transporter activity" BROAD [] synonym: "sialate/cation symporter activity" EXACT [] xref: GO:0015306 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0002753 name: drug:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out)." [TC:2.A.1.2.-, TC:2.A.1.3.-] subset: gosubset_prok synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" NARROW [] synonym: "drug:proton antiporter" EXACT [] xref: GO:0015307 is_a: CCO:F0002706 ! drug transporter activity is_a: CCO:F0002748 ! solute:hydrogen antiporter activity [Term] id: CCO:F0002754 name: amiloride:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out)." [TC:2.A.1.2.1] synonym: "amiloride:proton antiporter" EXACT [] xref: GO:0015308 is_a: CCO:F0002753 ! drug:hydrogen antiporter activity [Term] id: CCO:F0002755 name: cycloheximide:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out)." [TC:2.A.1.2.2] synonym: "cycloheximide:proton antiporter" EXACT [] xref: GO:0015309 is_a: CCO:F0002753 ! drug:hydrogen antiporter activity [Term] id: CCO:F0002756 name: benomyl:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out)." [TC:2.A.1.2.6] synonym: "benomyl:proton antiporter" EXACT [] xref: GO:0015310 is_a: CCO:F0002753 ! drug:hydrogen antiporter activity [Term] id: CCO:F0002757 name: monoamine:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out)." [TC:2.A.1.2.11, TC:2.A.1.2.12] synonym: "monoamine:proton antiporter" EXACT [] xref: GO:0015311 is_a: CCO:F0001958 ! monoamine transmembrane transporter activity is_a: CCO:F0002748 ! solute:hydrogen antiporter activity [Term] id: CCO:F0002758 name: polyamine:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out)." [TC:2.A.1.2.16] synonym: "polyamine:proton antiporter" EXACT [] xref: GO:0015312 is_a: CCO:F0002675 ! polyamine transmembrane transporter activity is_a: CCO:F0002748 ! solute:hydrogen antiporter activity [Term] id: CCO:F0002759 name: fluconazole:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out)." [TC:2.A.1.2.17] synonym: "fluconazole:proton antiporter" EXACT [] xref: GO:0015313 is_a: CCO:F0006071 ! azole:hydrogen antiporter activity [Term] id: CCO:F0002760 name: aminotriazole:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out)." [TC:2.A.1.3.1] synonym: "aminotriazole:proton antiporter" EXACT [] xref: GO:0015314 is_a: CCO:F0006071 ! azole:hydrogen antiporter activity [Term] id: CCO:F0002761 name: organophosphate:inorganic phosphate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out)." [TC:2.A.1.4.-] xref: GO:0015315 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0002762 name: phosphate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in)." [TC:2.A.1.9.-] synonym: "phosphate:proton symporter" EXACT [] xref: GO:0015317 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0002763 name: inorganic solute uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an inorganic solute from the outside of a cell to the inside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "inorganic uptake permease activity" EXACT [] xref: GO:0015318 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity is_a: CCO:F0002943 ! uptake transmembrane transporter activity [Term] id: CCO:F0002764 name: sodium:inorganic phosphate symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in)." [TC:2.A.1.14.6] xref: GO:0015319 is_a: CCO:F0001613 ! sodium:phosphate symporter activity [Term] id: CCO:F0002765 name: phosphate carrier activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate (cyt) + H+ (cyt) = phosphate (mitochondrion) + H+ (mitochondrion)." [TC:2.A.29.4.1, UniProtKB:P12234] xref: GO:0015320 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity [Term] id: CCO:F0002766 name: sodium-dependent phosphate transmembrane transporter activity namespace: molecular_function subset: gosubset_prok xref: GO:0015321 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity [Term] id: CCO:F0002767 name: secondary active oligopeptide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an oligopeptide or oligopeptides from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport] subset: gosubset_prok synonym: "oligopeptide porter activity" RELATED [] xref: GO:0015322 is_a: CCO:F0002672 ! oligopeptide transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002768 name: peptide-acetyl-CoA secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] synonym: "peptide-acetyl-CoA transporter activity" RELATED [] xref: GO:0015324 is_a: CCO:F0002671 ! peptide transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002769 name: acetyl-CoA:CoA antiporter activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out)." [TC:2.A.1.25.1] xref: GO:0015325 is_a: CCO:F0001974 ! acetyl-CoA transporter activity is_a: CCO:F0002749 ! solute:solute antiporter activity is_a: CCO:F0002768 ! peptide-acetyl-CoA secondary active transmembrane transporter activity [Term] id: CCO:F0002770 name: cationic amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a positively charged amino acid from one side of the membrane to the other." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0015326 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0001835 ! cation transmembrane transporter activity [Term] id: CCO:F0002771 name: cystine:glutamate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out)." [TC:2.A.3.8.5] xref: GO:0015327 is_a: CCO:F0001541 ! neutral L-amino acid secondary active transmembrane transporter activity is_a: CCO:F0001552 ! L-glutamate transmembrane transporter activity is_a: CCO:F0002658 ! L-cystine transmembrane transporter activity is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0002772 name: cystine secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] synonym: "cystine porter activity" RELATED [] synonym: "cystinosin" NARROW [] synonym: "lysosomal cystine transporter" NARROW [] xref: GO:0015328 is_a: CCO:F0001541 ! neutral L-amino acid secondary active transmembrane transporter activity is_a: CCO:F0002658 ! L-cystine transmembrane transporter activity [Term] id: CCO:F0002773 name: high affinity glutamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the high affinity transfer of glutamine from one side of the membrane to the other." [GOC:mtg_transport] synonym: "high affinity glutamine permease activity" RELATED [] xref: GO:0015330 is_a: CCO:F0001536 ! high affinity basic amino acid transmembrane transporter activity is_a: CCO:F0002660 ! L-glutamine transmembrane transporter activity [Term] id: CCO:F0002774 name: peptide:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in). Catalysis of the transfer of an peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement." [GOC:mtg_transport, TC:2.A.17.-.-] subset: gosubset_prok synonym: "peptide:proton symporter" EXACT [] xref: GO:0015333 is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0004314 ! proton-dependent peptide secondary active transmembrane transporter activity [Term] id: CCO:F0002775 name: high affinity oligopeptide transporter activity namespace: molecular_function def: "Catalysis of the transfer of oligopeptide from one side of the membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages." [GOC:mtg_transport] xref: GO:0015334 is_a: CCO:F0002672 ! oligopeptide transporter activity [Term] id: CCO:F0002776 name: zinc efflux active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.4.1.4, TC:2.A.4.2.3] synonym: "zinc efflux permease activity" BROAD [] xref: GO:0015341 is_a: CCO:F0001524 ! cation channel activity is_a: CCO:F0001601 ! zinc ion transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0004304 ! zinc efflux transmembrane transporter activity [Term] id: CCO:F0002777 name: siderophore-iron transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in)." [TC:2.A.1.16.-] subset: gosubset_prok synonym: "iron-siderophore transporter activity" EXACT [] synonym: "siderochrome-iron transporter activity" NARROW [] xref: GO:0015236 xref: GO:0015237 xref: GO:0015343 is_a: CCO:F0001599 ! iron ion transmembrane transporter activity is_a: CCO:F0005750 ! siderophore transporter activity [Term] id: CCO:F0002778 name: siderophore-iron (ferrioxamine) uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in)." [TC:2.A.1.16.1] synonym: "siderochrome-iron (ferrioxamine) uptake transporter" NARROW [] xref: GO:0015344 is_a: CCO:F0002777 ! siderophore-iron transmembrane transporter activity [Term] id: CCO:F0002779 name: ferric enterobactin:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in)." [TC:2.A.1.16.2] synonym: "ferric-enterobactin:proton symporter" EXACT [] xref: GO:0015345 is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002980 ! ferric-enterobactin transmembrane transporter activity [Term] id: CCO:F0002780 name: ferric triacetylfusarinine C:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in)." [TC:2.A.1.16.3] synonym: "ferric triacetylfusarinine C:proton symporter" EXACT [] xref: GO:0015346 is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002777 ! siderophore-iron transmembrane transporter activity is_a: CCO:F0002981 ! ferric triacetylfusarinine C transmembrane transporter activity [Term] id: CCO:F0002781 name: sodium-independent organic anion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner." [GOC:go_curators] xref: GO:0015347 is_a: CCO:F0001967 ! organic anion transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002782 name: thyroid hormone transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of thyroid hormones from one side of the membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine." [GOC:ai] xref: GO:0015349 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002783 name: methotrexate transporter activity namespace: molecular_function def: "Enables the directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of, within or between cells. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase." [GOC:ai] xref: GO:0015350 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0002784 name: bilirubin secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:mtg_transport] synonym: "bilirubin porter activity" RELATED [] synonym: "bilitranslocase" NARROW [] xref: GO:0015351 is_a: CCO:F0002604 ! bilirubin transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002785 name: secondary active sterol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sterol from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport] synonym: "sterol porter activity" RELATED [] xref: GO:0015352 is_a: CCO:F0002716 ! sterol transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002786 name: multidrug endosomal transmembrane transporter activity namespace: molecular_function xref: GO:0015353 is_a: CCO:F0002707 ! multidrug transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002787 name: polyspecific organic cation transmembrane transporter activity namespace: molecular_function xref: GO:0015354 is_a: CCO:F0001966 ! secondary active organic cation transmembrane transporter activity [Term] id: CCO:F0002788 name: secondary active monocarboxylate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism." [GOC:bf, GOC:jl] synonym: "monocarboxylate porter activity" RELATED [] xref: GO:0015355 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002789 name: acetate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in)." [TC:2.A.44.4.1] synonym: "acetate:proton symporter" EXACT [] synonym: "hydrogen:acetate symporter activity" EXACT [] xref: GO:0015357 xref: GO:0015360 is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0006055 ! acetate:cation symporter activity [Term] id: CCO:F0002790 name: low affinity sodium:dicarboxylate symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [TC:2.A.47.1.1] synonym: "low affinity sodium:dicarboxylate cotransporter activity" EXACT [] xref: GO:0015361 is_a: CCO:F0003597 ! sodium:dicarboxylate symporter activity [Term] id: CCO:F0002791 name: high affinity sodium:dicarboxylate symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [TC:2.A.47.1.4] synonym: "high affinity sodium:dicarboxylate cotransporter activity" EXACT [] xref: GO:0015362 is_a: CCO:F0003597 ! sodium:dicarboxylate symporter activity [Term] id: CCO:F0002792 name: dicarboxylate:inorganic phosphate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out)." [TC:2.A.29.2.3] xref: GO:0015364 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity is_a: CCO:F0002746 ! antiporter activity [Term] id: CCO:F0002793 name: malate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in)." [TC:2.A.16.2.1] synonym: "malate:proton symporter" EXACT [] xref: GO:0015366 is_a: CCO:F0002617 ! malate transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0002794 name: oxoglutarate:malate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out)." [TC:2.A.29.2.1] xref: GO:0015367 is_a: CCO:F0002749 ! solute:solute antiporter activity is_a: CCO:F0002750 ! anion:anion antiporter activity [Term] id: CCO:F0002795 name: calcium:cation antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in)." [TC:2.A.19.-.-] subset: gosubset_prok xref: GO:0015368 is_a: CCO:F0002886 ! cation:cation antiporter activity [Term] id: CCO:F0002796 name: calcium:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in)." [TC:2.A.19.2.-] subset: gosubset_prok synonym: "calcium:proton antiporter" EXACT [] xref: GO:0015369 is_a: CCO:F0002795 ! calcium:cation antiporter activity is_a: CCO:F0008064 ! metal ion:hydrogen antiporter activity [Term] id: CCO:F0002797 name: solute:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in)." [GOC:ai] subset: gosubset_prok synonym: "proline/glycine/betaine:hydrogen/sodium symporter activity" NARROW [] xref: GO:0015370 is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0002798 name: galactose:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in)." [TC:2.A.21.3.-] xref: GO:0015371 is_a: CCO:F0001580 ! galactose transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0002799 name: monovalent anion:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in)." [TC:2.A.21.5.-] xref: GO:0015373 is_a: CCO:F0002745 ! anion:cation symporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0002800 name: neutral, cationic amino acid:sodium:chloride symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/cationic amino acid(out) + Na+(out) + Cl-(out) = neutral/cationic amino acid(in) + Na+(in) + Cl-(in)." [TC:2.A.22.2.3] xref: GO:0015374 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity [Term] id: CCO:F0002801 name: glycine:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in)." [GOC:ai] xref: GO:0015375 xref: GO:0015656 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0001541 ! neutral L-amino acid secondary active transmembrane transporter activity is_a: CCO:F0002661 ! glycine transmembrane transporter activity [Term] id: CCO:F0002802 name: cation:chloride symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in)." [TC:2.A.30.-.-] synonym: "cation:chloride cotransporter activity" EXACT [] xref: GO:0015377 is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0002803 name: sodium:chloride symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in)." [TC:2.A.30.4.-] xref: GO:0015378 is_a: CCO:F0002802 ! cation:chloride symporter activity [Term] id: CCO:F0002804 name: potassium:chloride symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in)." [TC:2.A.30.5.-] xref: GO:0015379 is_a: CCO:F0002802 ! cation:chloride symporter activity [Term] id: CCO:F0002805 name: anion exchanger activity namespace: molecular_function synonym: "bicarbonate:chloride antiporter" NARROW [] xref: GO:0015380 xref: GO:0015384 is_a: CCO:F0002584 ! bicarbonate transmembrane transporter activity is_a: CCO:F0002586 ! chloride transmembrane transporter activity is_a: CCO:F0002750 ! anion:anion antiporter activity [Term] id: CCO:F0002806 name: high affinity sulfate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the secondary active high affinity transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations." [GOC:mtg_transport] synonym: "high affinity sulfate permease activity" RELATED [] synonym: "high affinity sulphate permease activity" EXACT [] xref: GO:0015381 is_a: CCO:F0001811 ! secondary active sulfate transmembrane transporter activity [Term] id: CCO:F0002807 name: sodium:sulfate symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in)." [TC:2.A.47.1.2] synonym: "sodium:sulfate cotransporter activity" EXACT [] synonym: "sodium:sulphate symporter activity" EXACT [] xref: GO:0015382 is_a: CCO:F0001811 ! secondary active sulfate transmembrane transporter activity is_a: CCO:F0002562 ! sodium ion transmembrane transporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0002808 name: sulfate:bicarbonate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out)." [TC:2.A.53.2.2] synonym: "sulphate:bicarbonate antiporter activity" EXACT [] xref: GO:0015383 is_a: CCO:F0001811 ! secondary active sulfate transmembrane transporter activity is_a: CCO:F0002584 ! bicarbonate transmembrane transporter activity is_a: CCO:F0002750 ! anion:anion antiporter activity [Term] id: CCO:F0002809 name: sodium:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [TC:2.A.35.1.1, TC:2.A.36.-.-] subset: gosubset_prok synonym: "pH-dependent sodium:hydrogen antiporter activity" NARROW [] synonym: "pH-dependent sodium:proton antiporter" NARROW [] synonym: "sodium/hydrogen antiporter" EXACT [] synonym: "sodium:hydrogen exchange activity" EXACT [] synonym: "sodium:hydrogen exchanger" EXACT [] synonym: "sodium:proton antiporter" EXACT [] xref: GO:0015385 xref: GO:0015502 is_a: CCO:F0001614 ! monovalent cation:proton antiporter activity [Term] id: CCO:F0002810 name: potassium:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in)." [TC:2.A.37.-.-] subset: gosubset_prok synonym: "potassium:proton antiporter" EXACT [] xref: GO:0015386 is_a: CCO:F0001614 ! monovalent cation:proton antiporter activity is_a: CCO:F0004259 ! potassium ion antiporter activity [Term] id: CCO:F0002811 name: potassium:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in)." [TC:2.A.38.-.-] synonym: "potassium:proton symporter" EXACT [] xref: GO:0015387 is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0004258 ! potassium ion symporter activity [Term] id: CCO:F0002812 name: potassium uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of potassium from the outside of a cell to the inside of the cell across a membrane: K+(out) + energy = K+(in)." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.72.2.-] synonym: "potassium uptake permease activity" EXACT [] xref: GO:0015388 is_a: CCO:F0002560 ! potassium ion transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0002943 ! uptake transmembrane transporter activity [Term] id: CCO:F0002813 name: pyrimidine- and adenine-specific:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in)." [TC:2.A.41.2.3] xref: GO:0015389 is_a: CCO:F0001573 ! purine transmembrane transporter activity is_a: CCO:F0001576 ! pyrimidine transmembrane transporter activity is_a: CCO:F0001607 ! nucleoside:sodium symporter activity [Term] id: CCO:F0002814 name: purine-specific nucleoside:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in)." [TC:2.A.41.2.1] xref: GO:0015390 is_a: CCO:F0001607 ! nucleoside:sodium symporter activity [Term] id: CCO:F0002815 name: nucleobase:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in)." [GOC:ai] subset: gosubset_prok xref: GO:0015391 is_a: CCO:F0002677 ! nucleobase transmembrane transporter activity is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0002816 name: uridine:hydrogen ion symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in)." [GOC:mtg_transport] synonym: "nucleoside (uridine) permease activity" RELATED [] xref: GO:0015394 is_a: CCO:F0001576 ! pyrimidine transmembrane transporter activity is_a: CCO:F0002684 ! uridine transmembrane transporter activity is_a: CCO:F0002815 ! nucleobase:cation symporter activity is_a: CCO:F0002899 ! nucleoside:hydrogen symporter activity [Term] id: CCO:F0002817 name: nucleoside transmembrane transporter activity, down a concentration gradient namespace: molecular_function def: "Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient." [PMID:10353709, PMID:11749958, PMID:12446811] synonym: "equilibrative nucleoside transporter" EXACT [] xref: GO:0015395 is_a: CCO:F0001567 ! nucleoside transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002818 name: equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-sensitive activity namespace: molecular_function xref: GO:0015396 is_a: CCO:F0002817 ! nucleoside transmembrane transporter activity, down a concentration gradient [Term] id: CCO:F0002819 name: equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-insensitive activity namespace: molecular_function xref: GO:0015397 is_a: CCO:F0002817 ! nucleoside transmembrane transporter activity, down a concentration gradient [Term] id: CCO:F0002820 name: high affinity secondary active ammonium transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mtg_transport] xref: GO:0015398 is_a: CCO:F0001972 ! ammonium transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002821 name: primary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources." [GOC:mtg_transport, ISBN:0815340729, TC:3.-.-.-.-] subset: gosubset_prok synonym: "primary active transporter" RELATED [] xref: GO:0015399 xref: TC:3 is_a: CCO:F0004251 ! active transmembrane transporter activity [Term] id: CCO:F0002822 name: low affinity secondary active ammonium transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations." [GOC:mtg_transport, ISBN:0815340729] synonym: "low affinity ammonium transmembrane transporter activity" RELATED [] xref: GO:0015400 is_a: CCO:F0001972 ! ammonium transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002823 name: urea:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in)." [TC:2.A.21.6.1] synonym: "urea active transmembrane transporter activity" EXACT [] xref: GO:0015401 is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0002824 name: thiamin uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of thiamin from the outside of a cell to the inside across a membrane." [GOC:mtg_transport] synonym: "thiamine uptake transporter activity" EXACT [] xref: GO:0015403 is_a: CCO:F0002704 ! thiamin transmembrane transporter activity is_a: CCO:F0002943 ! uptake transmembrane transporter activity [Term] id: CCO:F0002825 name: ion-gradient-driven energizer activity namespace: molecular_function subset: gosubset_prok xref: GO:0015404 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002826 name: P-P-bond-hydrolysis-driven transmembrane transporter activity namespace: molecular_function def: "Primary active transport of a solute across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.A.-.-.-] subset: gosubset_prok synonym: "P-P-bond-hydrolysis-driven transporters" EXACT [] xref: GO:0015405 xref: TC:3.A is_a: CCO:F0002821 ! primary active transmembrane transporter activity [Term] id: CCO:F0002827 name: monosaccharide-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported." [EC:3.6.3.17] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (monosaccharide-importing)" EXACT [EC:3.6.3.17] synonym: "monosaccharide ABC transporter" NARROW [] synonym: "monosaccharide-importing ATPase activity" NARROW [] xref: EC:3.6.3.17 xref: GO:0015407 xref: MetaCyc:3.6.3.17-RXN is_a: CCO:F0002622 ! monosaccharide transmembrane transporter activity is_a: CCO:F0002971 ! carbohydrate-importing ATPase activity [Term] id: CCO:F0002828 name: ferric-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in)." [EC:3.6.3.30] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (ferric-ion-transporting)" EXACT [EC:3.6.3.30] synonym: "Fe3+-transporting ATPase activity" EXACT [EC:3.6.3.30] synonym: "ferric ABC transporter" NARROW [] synonym: "ferric transporting ATPase activity" EXACT [] xref: EC:3.6.3.30 xref: GO:0015408 xref: MetaCyc:3.6.3.30-RXN is_a: CCO:F0002571 ! ferric iron transmembrane transporter activity is_a: CCO:F0004186 ! cation-transporting ATPase activity [Term] id: CCO:F0002829 name: manganese-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in)." [EC:3.6.3.35] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ABC-type manganese permease complex" RELATED [EC:3.6.3.35] synonym: "ATP phosphohydrolase (manganese-importing)" EXACT [EC:3.6.3.35] synonym: "manganese ABC transporter" NARROW [] synonym: "manganese transporting ATPase activity" EXACT [] xref: EC:3.6.3.35 xref: GO:0015410 xref: MetaCyc:3.6.3.35-RXN is_a: CCO:F0001600 ! manganese ion transmembrane transporter activity is_a: CCO:F0004186 ! cation-transporting ATPase activity [Term] id: CCO:F0002830 name: taurine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in)." [EC:3.6.3.36] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (taurine-importing)" EXACT [EC:3.6.3.36] synonym: "taurine (2-aminoethane sulfonate) porter activity" EXACT [] synonym: "taurine ABC transporter" NARROW [] xref: EC:3.6.3.36 xref: GO:0015411 xref: MetaCyc:3.6.3.36-RXN is_a: CCO:F0001594 ! taurine transmembrane transporter activity is_a: CCO:F0002843 ! amino acid-transporting ATPase activity [Term] id: CCO:F0002831 name: molybdate transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in)." [EC:3.6.3.29] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (molybdate-importing)" EXACT [EC:3.6.3.29] synonym: "molybdate ABC transporter" NARROW [] synonym: "molybdate porter activity" EXACT [] synonym: "molybdate transporting ATPase activity" EXACT [] synonym: "molybdate-transporting ATPase activity" EXACT [EC:3.6.3.29] xref: EC:3.6.3.29 xref: GO:0015412 xref: MetaCyc:3.6.3.29-RXN is_a: CCO:F0002577 ! molybdate ion transmembrane transporter activity is_a: CCO:F0005824 ! anion transmembrane-transporting ATPase activity [Term] id: CCO:F0002832 name: nickel-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in)." [EC:3.6.3.24] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (nickel-importing)" EXACT [EC:3.6.3.24] synonym: "nickel ABC transporter" NARROW [] synonym: "nickel porter activity" EXACT [] synonym: "nickel transporting ATPase activity" EXACT [] xref: EC:3.6.3.24 xref: GO:0015413 xref: MetaCyc:3.6.3.24-RXN is_a: CCO:F0002578 ! nickel ion transmembrane transporter activity is_a: CCO:F0004186 ! cation-transporting ATPase activity [Term] id: CCO:F0002833 name: nitrate transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in)." [EC:3.6.3.26] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (nitrate-importing)" EXACT [EC:3.6.3.26] synonym: "nitrate ABC transporter" NARROW [] synonym: "nitrate transporting ATPase activity" EXACT [] synonym: "nitrate-transporting ATPase activity" EXACT [EC:3.6.3.26] xref: EC:3.6.3.26 xref: GO:0015414 xref: MetaCyc:3.6.3.26-RXN is_a: CCO:F0002590 ! nitrate transmembrane transporter activity is_a: CCO:F0005824 ! anion transmembrane-transporting ATPase activity [Term] id: CCO:F0002834 name: phosphate transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in)." [EC:3.6.3.27] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ABC phosphate transporter activity" NARROW [EC:3.6.3.27] synonym: "ATP phosphohydrolase (phosphate-importing)" EXACT [EC:3.6.3.27] synonym: "phosphate ABC transporter" NARROW [] synonym: "phosphate porter activity" EXACT [] synonym: "phosphate transporting ATPase activity" EXACT [] synonym: "phosphate-transporting ATPase activity" EXACT [EC:3.6.3.27] xref: EC:3.6.3.27 xref: GO:0015415 xref: MetaCyc:3.6.3.27-RXN is_a: CCO:F0002592 ! phosphate transmembrane transporter activity is_a: CCO:F0005824 ! anion transmembrane-transporting ATPase activity [Term] id: CCO:F0002835 name: phosphonate transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)." [EC:3.6.3.28] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (phosphonate-transporting)" EXACT [EC:3.6.3.28] synonym: "phosphonate ABC transporter" NARROW [] synonym: "phosphonate transporting ATPase activity" EXACT [] synonym: "phosphonate-transporting ATPase activity" EXACT [EC:3.6.3.28] xref: EC:3.6.3.28 xref: GO:0015416 xref: MetaCyc:3.6.3.28-RXN is_a: CCO:F0002967 ! phosphonate transmembrane transporter activity is_a: CCO:F0002968 ! organophosphate ester transmembrane transporter activity is_a: CCO:F0005824 ! anion transmembrane-transporting ATPase activity [Term] id: CCO:F0002836 name: polyamine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in)." [EC:3.6.3.31] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (polyamine-importing) activity" EXACT [EC:3.6.3.31] synonym: "polyamine ABC transporter" NARROW [] synonym: "polyamine porter activity" EXACT [] synonym: "polyamine-importing ATPase activity" NARROW [] xref: EC:3.6.3.31 xref: GO:0015417 is_a: CCO:F0002675 ! polyamine transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002837 name: quaternary-ammonium-compound-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in)." [EC:3.6.3.32] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (quaternary-amine-importing) activity" EXACT [EC:3.6.3.32] synonym: "glycine betaine/proline porter activity" RELATED [] synonym: "quaternary amine uptake transporter activity" EXACT [] synonym: "quaternary-amine-transporting ATPase activity" EXACT [] synonym: "quaternary-ammonium-compound ABC transporter" NARROW [] xref: EC:3.6.3.32 xref: GO:0015418 xref: MetaCyc:3.6.3.32-RXN is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002838 name: sulfate transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in)." [EC:3.6.3.25] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (sulfate-importing) activity" EXACT [EC:3.6.3.25] synonym: "sulfate ABC transporter" NARROW [] synonym: "sulfate transporting ATPase activity" EXACT [] synonym: "sulfate-transporting ATPase activity" EXACT [EC:3.6.3.25] synonym: "sulfate/thiosulfate porter activity" EXACT [] synonym: "sulphate transporting ATPase activity" EXACT [] synonym: "sulphate-transporting ATPase activity" EXACT [] xref: EC:3.6.3.25 xref: GO:0015419 xref: MetaCyc:3.6.3.25-RXN is_a: CCO:F0002594 ! sulfate transmembrane transporter activity is_a: CCO:F0005824 ! anion transmembrane-transporting ATPase activity [Term] id: CCO:F0002839 name: cobalamin-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + cobalamin(out) = ADP + phosphate + cobalamin(in). Cobalamin = vitamin B12." [EC:3.6.3.33] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (vitamin B12-importing)" EXACT [EC:3.6.3.33] synonym: "cobalamin ABC transporter" NARROW [] synonym: "cobalamin porter activity" EXACT [] synonym: "vitamin B12 porter activity" EXACT [] synonym: "vitamin B12-transporting ATPase activity" EXACT [] xref: EC:3.6.3.33 xref: GO:0015420 xref: MetaCyc:3.6.3.33-RXN is_a: CCO:F0002705 ! cobalamin transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002840 name: oligopeptide-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in)." [EC:3.6.3.23] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (oligopeptide-importing)" EXACT [EC:3.6.3.23] synonym: "oligopeptide ABC transporter" NARROW [] synonym: "oligopeptide permease activity" RELATED [EC:3.6.3.23] xref: EC:3.6.3.23 xref: GO:0015421 xref: MetaCyc:3.6.3.23-RXN is_a: CCO:F0002672 ! oligopeptide transporter activity is_a: CCO:F0002855 ! peptide-transporting ATPase activity [Term] id: CCO:F0002841 name: oligosaccharide-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in)." [EC:3.6.3.18] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (disaccharide-importing)" EXACT [EC:3.6.3.18] synonym: "oligosaccharide ABC transporter" NARROW [] xref: EC:3.6.3.18 xref: GO:0015422 xref: MetaCyc:3.6.3.18-RXN is_a: CCO:F0002634 ! oligosaccharide transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002842 name: maltose-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in)." [EC:3.6.3.19] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (maltose-importing)" EXACT [EC:3.6.3.19] synonym: "maltose ABC transporter" NARROW [] xref: EC:3.6.3.19 xref: GO:0015423 xref: MetaCyc:3.6.3.19-RXN is_a: CCO:F0001589 ! maltose transmembrane transporter activity is_a: CCO:F0002841 ! oligosaccharide-transporting ATPase activity [Term] id: CCO:F0002843 name: amino acid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out)." [GOC:ai, GOC:mah] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "amino acid ABC transporter" NARROW [] xref: GO:0015424 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity is_a: CCO:F0004647 ! amine-transporting ATPase activity [Term] id: CCO:F0002844 name: nonpolar-amino acid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in)." [EC:3.6.3.22] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (nonpolar-amino-acid-transporting) activity" EXACT [EC:3.6.3.22] synonym: "leucine/isoleucine/valine porter activity" RELATED [] synonym: "nonpolar amino acid-transporting ATPase activity" EXACT [] synonym: "nonpolar-amino acid ABC transporter" NARROW [] synonym: "nonpolar-amino-acid-transporting ATPase activity" EXACT [] xref: EC:3.6.3.22 xref: GO:0015425 xref: MetaCyc:3.6.3.22-RXN is_a: CCO:F0002843 ! amino acid-transporting ATPase activity [Term] id: CCO:F0002845 name: polar-amino acid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in)." [EC:3.6.3.21] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (polar-amino-acid-importing) activity" EXACT [EC:3.6.3.21] synonym: "cystine/diaminopimelate porter activity" RELATED [] synonym: "glutamate/aspartate porter activity" RELATED [] synonym: "histidine permease activity" NARROW [EC:3.6.3.21] synonym: "histidine/arginine/lysine/ornithine porter activity" RELATED [] synonym: "polar amino acid uptake transporter activity" EXACT [] synonym: "polar amino acid-importing ATPase activity" EXACT [] synonym: "polar-amino acid ABC transporter" NARROW [] synonym: "polar-amino acid-importing ATPase activity" EXACT [] synonym: "polar-amino-acid-transporting ATPase activity" EXACT [EC:3.6.3.21] xref: EC:3.6.3.21 xref: GO:0015426 xref: MetaCyc:3.6.3.21-RXN is_a: CCO:F0002843 ! amino acid-transporting ATPase activity [Term] id: CCO:F0002846 name: glycerol-3-phosphate-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in)." [EC:3.6.3.20] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (glycerol-3-phosphate-importing)" EXACT [EC:3.6.3.20] synonym: "glycerol-3-phosphate ABC transporter" NARROW [] xref: EC:3.6.3.20 xref: GO:0015430 xref: MetaCyc:3.6.3.20-RXN is_a: CCO:F0002646 ! glycerol-3-phosphate transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002847 name: glutathione S-conjugate-exporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) = ADP + phosphate + glutathione S-conjugate(out)." [GOC:jl, PMID:1455517] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP-dependent glutathione S-conjugate export pump" EXACT [] synonym: "conjugate transporter activity" BROAD [] synonym: "GS-X pump" EXACT [] synonym: "MRP1/GS-X pump" EXACT [] xref: GO:0015431 is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002848 name: bile acid-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O = bile acid(out) + ADP + phosphate." [TC:3.A.1.207.2] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "bile acid porter activity" NARROW [] xref: GO:0015432 is_a: CCO:F0002602 ! bile acid transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002849 name: peptide antigen-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate." [TC:3.A.1.209.1] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "major histocompatibility peptide transporter activity" EXACT [] synonym: "peptide antigen ABC transporter" NARROW [] synonym: "peptide antigen transporter activity" BROAD [] xref: GO:0015433 is_a: CCO:F0002855 ! peptide-transporting ATPase activity [Term] id: CCO:F0002850 name: cadmium-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole)." [EC:3.6.3.46] subset: gosubset_prok synonym: "ATP phosphohydrolase (heavy-metal-exporting)" EXACT [EC:3.6.3.46] synonym: "cadmium ABC transporter" NARROW [] synonym: "yeast cadmium factor" RELATED [EC:3.6.3.46] xref: EC:3.6.3.46 xref: GO:0015434 is_a: CCO:F0002566 ! cadmium ion transmembrane transporter activity [Term] id: CCO:F0002851 name: capsular-polysaccharide-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out)." [EC:3.6.3.38] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (capsular-polysaccharide-exporting)" EXACT [EC:3.6.3.38] synonym: "capsular-polysaccharide ABC transporter" NARROW [] xref: EC:3.6.3.38 xref: GO:0015436 xref: MetaCyc:3.6.3.38-RXN is_a: CCO:F0002638 ! capsular-polysaccharide transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002852 name: lipopolysaccharide-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipopolysaccharide(in) = ADP + phosphate + lipopolysaccharide(out)." [EC:3.6.3.39] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (lipopolysaccharide-exporting)" EXACT [EC:3.6.3.39] synonym: "lipopolysaccharide ABC transporter" NARROW [] synonym: "LPS-transporting ATPase activity" EXACT [] xref: EC:3.6.3.39 xref: GO:0015437 xref: MetaCyc:3.6.3.39-RXN is_a: CCO:F0002692 ! lipopolysaccharide transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002853 name: teichoic-acid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out)." [EC:3.6.3.40] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (teichoic-acid-exporting)" EXACT [EC:3.6.3.40] synonym: "teichoic-acid ABC transporter" NARROW [] xref: EC:3.6.3.40 xref: GO:0015438 xref: MetaCyc:3.6.3.40-RXN is_a: CCO:F0002639 ! teichoic acid transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002854 name: heme-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out)." [EC:3.6.3.41] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (heme-exporting)" EXACT [EC:3.6.3.41] synonym: "haem-transporting ATPase activity" EXACT [] synonym: "heme ABC transporter" NARROW [] xref: EC:3.6.3.41 xref: GO:0015439 xref: MetaCyc:3.6.3.41-RXN is_a: CCO:F0002702 ! heme transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002855 name: peptide-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria." [EC:3.6.3.43] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (peptide-exporting)" EXACT [EC:3.6.3.43] synonym: "peptide ABC transporter" NARROW [] xref: EC:3.6.3.43 xref: GO:0015440 xref: MetaCyc:3.6.3.43-RXN is_a: CCO:F0002671 ! peptide transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002856 name: beta-glucan-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out)." [EC:3.6.3.42] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (beta-glucan-exporting)" EXACT [EC:3.6.3.42] synonym: "beta-glucan ABC transporter" NARROW [] xref: EC:3.6.3.42 xref: GO:0015441 xref: MetaCyc:3.6.3.42-RXN is_a: CCO:F0002637 ! beta-glucan transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002857 name: magnesium-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) = ADP + phosphate + Mg2+(in)." [EC:3.6.3.2] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (Mg2+-importing)" EXACT [EC:3.6.3.2] synonym: "magnesium importing ATPase activity" EXACT [] synonym: "magnesium-translocating P-type ATPase activity" RELATED [EC:3.6.3.2] synonym: "Mg(2+)-importing ATPase activity" EXACT [EC:3.6.3.2] synonym: "Mg2+-importing ATPase activity" EXACT [EC:3.6.3.2] synonym: "mg2+-importing ATPase activity" EXACT [EC:3.6.3.2] xref: EC:3.6.3.2 xref: GO:0015444 xref: MetaCyc:3.6.3.2-RXN is_a: CCO:F0002575 ! magnesium ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0002858 name: silver-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) = ADP + phosphate + Ag+(out)." [EC:3.6.3.53] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "Ag+-exporting ATPase activity" EXACT [EC:3.6.3.53] synonym: "ATP phosphohydrolase (Ag+-exporting)" EXACT [EC:3.6.3.53] synonym: "silver exporting ATPase activity" EXACT [] xref: EC:3.6.3.53 xref: GO:0015445 xref: MetaCyc:3.6.3.53-RXN is_a: CCO:F0002561 ! silver ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0002859 name: arsenite transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out)." [EC:3.6.3.16] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "arsenical pump-driving ATPase activity" EXACT [EC:3.6.3.16] synonym: "arsenical resistance ATPase activity" EXACT [EC:3.6.3.16] synonym: "arsenical resistance efflux pump" EXACT [] synonym: "arsenite ABC transporter" NARROW [] synonym: "arsenite transporting ATPase activity" EXACT [] synonym: "arsenite-translocating ATPase activity" EXACT [EC:3.6.3.16] synonym: "arsenite-transporting ATPase activity" EXACT [EC:3.6.3.16] synonym: "ATP phosphohydrolase (arsenite-exporting) activity" EXACT [EC:3.6.3.16] xref: EC:3.6.3.16 xref: GO:0015446 xref: MetaCyc:3.6.3.16-RXN is_a: CCO:F0001950 ! arsenite secondary active transmembrane transporter activity is_a: CCO:F0004186 ! cation-transporting ATPase activity is_a: CCO:F0005824 ! anion transmembrane-transporting ATPase activity [Term] id: CCO:F0002860 name: P-P-bond-hydrolysis-driven protein transmembrane transporter activity namespace: molecular_function def: "Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "protein translocase activity" EXACT [] xref: GO:0015450 is_a: CCO:F0001832 ! protein transmembrane transporter activity is_a: CCO:F0002826 ! P-P-bond-hydrolysis-driven transmembrane transporter activity is_a: CCO:F0004305 ! macromolecule transmembrane transporter activity [Term] id: CCO:F0002861 name: decarboxylation-driven active transmembrane transporter activity namespace: molecular_function def: "Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.B.-.-.-] subset: gosubset_prok synonym: "Decarboxylation-driven transporters" RELATED [] xref: GO:0015451 xref: TC:3.B is_a: CCO:F0002821 ! primary active transmembrane transporter activity [Term] id: CCO:F0002862 name: methyl transfer-driven active transmembrane transporter activity namespace: molecular_function def: "Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.C.-.-.-] synonym: "Methyltransfer-driven transporters" EXACT [] xref: GO:0015452 xref: TC:3.C is_a: CCO:F0002821 ! primary active transmembrane transporter activity [Term] id: CCO:F0002863 name: oxidoreduction-driven active transmembrane transporter activity namespace: molecular_function def: "Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.D.-.-.-] subset: gosubset_prok synonym: "Oxidoreduction-driven transporters" EXACT [] xref: GO:0015453 xref: TC:3.D is_a: CCO:F0002821 ! primary active transmembrane transporter activity [Term] id: CCO:F0002864 name: light-driven active transmembrane transporter activity namespace: molecular_function def: "Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source." [GOC:mtg_transport, ISBN:0815340729, TC:3.E.-.-.-] synonym: "Light absorption-driven transporters" EXACT [] synonym: "light-driven pumps" EXACT [] xref: GO:0015454 xref: TC:3.E is_a: CCO:F0002821 ! primary active transmembrane transporter activity [Term] id: CCO:F0002865 name: auxiliary transport protein activity namespace: molecular_function def: "Facilitates transport across one or more biological membranes but do not themselves participate directly in transport. These proteins always function in conjunction with one or more established transport systems. They may provide a function connected with energy coupling to transport, play a structural role in complex formation, serve a biogenic or stability function or function in regulation." [TC:8.A.-.-.-] subset: goslim_pir subset: gosubset_prok xref: GO:0015457 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0002866 name: low voltage-gated potassium channel auxiliary protein activity namespace: molecular_function synonym: "low voltage-dependent potassium channel auxiliary protein activity" EXACT [] xref: GO:0015458 is_a: CCO:F0002865 ! auxiliary transport protein activity [Term] id: CCO:F0002867 name: potassium channel regulator activity namespace: molecular_function xref: GO:0015459 is_a: CCO:F0003086 ! channel regulator activity [Term] id: CCO:F0002868 name: transport accessory protein activity namespace: molecular_function xref: GO:0015460 is_a: CCO:F0002865 ! auxiliary transport protein activity [Term] id: CCO:F0002869 name: protein-transmembrane transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in)." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "pilin/fimbrilin exporter activity" NARROW [] synonym: "protein ABC transporter" NARROW [] synonym: "protein-transporting ATPase activity" EXACT [] xref: GO:0015462 is_a: CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002870 name: acetylcholine receptor activity namespace: molecular_function def: "Combining with acetylcholine to initiate a change in cell activity." [GOC:jl] xref: GO:0015464 is_a: CCO:F0001240 ! transmembrane receptor activity is_a: CCO:F0004488 ! neurotransmitter receptor activity is_a: CCO:F0005634 ! acetylcholine binding [Term] id: CCO:F0002871 name: G-protein activated inward rectifier potassium channel activity namespace: molecular_function synonym: "G protein activated inward rectifier potassium channel activity" EXACT [] synonym: "G-protein-activated inward rectifier potassium channel activity" EXACT [] xref: GO:0015467 is_a: CCO:F0001510 ! inward rectifier potassium channel activity [Term] id: CCO:F0002872 name: nucleoside-specific channel forming porin activity namespace: molecular_function def: "Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] xref: GO:0015471 is_a: CCO:F0002739 ! porin activity [Term] id: CCO:F0002873 name: fimbrial usher porin activity namespace: molecular_function def: "A porin that acts in the assembly of fimbria together with fimbrial chaperone." [TC:1.B.11.-.-] xref: GO:0015473 is_a: CCO:F0002739 ! porin activity [Term] id: CCO:F0002874 name: autotransporter activity namespace: molecular_function def: "Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively." [GOC:mtg_transport, ISBN:0815340729, TC:1.B.12.-.-] subset: gosubset_prok xref: GO:0015474 is_a: CCO:F0001997 ! protein transporter activity is_a: CCO:F0002739 ! porin activity [Term] id: CCO:F0002875 name: adhesin autotransporter activity namespace: molecular_function def: "Catalysis of the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0015475 is_a: CCO:F0002874 ! autotransporter activity [Term] id: CCO:F0002876 name: hemaglutinin autotransporter activity namespace: molecular_function def: "Catalysis of the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0015476 is_a: CCO:F0002874 ! autotransporter activity [Term] id: CCO:F0002877 name: oligosaccharide transporting porin activity namespace: molecular_function def: "Catalysis of the transfer of oligosaccharide, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] synonym: "raffinose porin" NARROW [] xref: GO:0015478 is_a: CCO:F0002634 ! oligosaccharide transmembrane transporter activity is_a: CCO:F0002739 ! porin activity [Term] id: CCO:F0002878 name: maltose transporting porin activity namespace: molecular_function def: "Catalysis of the transfer of maltose from one side of the membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] subset: gosubset_prok synonym: "maltoporin" EXACT [] xref: GO:0015481 is_a: CCO:F0001589 ! maltose transmembrane transporter activity is_a: CCO:F0002739 ! porin activity [Term] id: CCO:F0002879 name: long-chain fatty acid transporting porin activity namespace: molecular_function def: "Catalysis of the transfer of long-chain fatty acids from one side of the membrane to the other. Long-chain fatty acids have a chain length of greater than 12 carbons. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria." [GOC:mtg_transport] xref: GO:0015483 is_a: CCO:F0001557 ! long-chain fatty acid transporter activity is_a: CCO:F0002739 ! porin activity [Term] id: CCO:F0002880 name: cholesterol binding namespace: molecular_function def: "Interacting selectively with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0015485 is_a: CCO:F0005049 ! sterol binding [Term] id: CCO:F0002881 name: glycoside-pentoside-hexuronide:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+." [TC:2.A.2.-.-] xref: GO:0015486 is_a: CCO:F0001605 ! cation:sugar symporter activity [Term] id: CCO:F0002882 name: melibiose:monovalent cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in)." [TC:2.A.2.1.1] subset: gosubset_prok synonym: "melibiose permease activity" RELATED [] xref: GO:0015487 is_a: CCO:F0002633 ! melibiose transmembrane transporter activity is_a: CCO:F0002881 ! glycoside-pentoside-hexuronide:cation symporter activity [Term] id: CCO:F0002883 name: glucuronide:monovalent cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in)." [TC:2.A.2.3.1] synonym: "glucuronoside permease activity" RELATED [] xref: GO:0015488 is_a: CCO:F0002641 ! glucuronoside transmembrane transporter activity is_a: CCO:F0002881 ! glycoside-pentoside-hexuronide:cation symporter activity [Term] id: CCO:F0002884 name: putrescine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of putrescine from one side of the membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine." [GOC:ai] subset: gosubset_prok xref: GO:0015489 is_a: CCO:F0002675 ! polyamine transmembrane transporter activity [Term] id: CCO:F0002885 name: cadaverine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cadaverine, 1,5-pentanediamine, from one side of the membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015490 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0002886 name: cation:cation antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out)." [GOC:ai] subset: gosubset_prok xref: GO:0015491 is_a: CCO:F0002747 ! solute:cation antiporter activity [Term] id: CCO:F0002887 name: phenylalanine:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in)." [TC:2.A.3.1.1] synonym: "phenylalanine:proton symporter" EXACT [] xref: GO:0015492 is_a: CCO:F0002666 ! L-phenylalanine transmembrane transporter activity is_a: CCO:F0002889 ! aromatic amino acid:hydrogen symporter activity [Term] id: CCO:F0002888 name: lysine:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in)." [TC:2.A.3.1.2] synonym: "lysine:proton symporter" EXACT [] xref: GO:0015493 is_a: CCO:F0001533 ! hydrogen:amino acid symporter activity is_a: CCO:F0002663 ! L-lysine transmembrane transporter activity [Term] id: CCO:F0002889 name: aromatic amino acid:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in)." [TC:2.A.3.1.3] synonym: "aromatic amino acid:proton symporter" EXACT [] xref: GO:0015494 is_a: CCO:F0001533 ! hydrogen:amino acid symporter activity is_a: CCO:F0002650 ! aromatic amino acid transmembrane transporter activity [Term] id: CCO:F0002890 name: gamma-aminobutyric acid:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in)." [TC:2.A.18.5.1, TC:2.A.3.1.4, TC:2.A.3.4.2] comment: See also the molecular function term 'neurotransmitter transporter activity ; GO:0005326'. synonym: "4-aminobutanoate:hydrogen symporter activity" EXACT [] synonym: "4-aminobutanoate:proton symporter activty" EXACT [] synonym: "4-aminobutyrate:hydrogen symporter activity" EXACT [] synonym: "4-aminobutyrate:proton symporter activity" EXACT [] synonym: "GABA:hydrogen symporter activity" EXACT [] synonym: "GABA:proton symporter activity" EXACT [] synonym: "gamma-aminobutyric acid permease activity" EXACT [] synonym: "gamma-aminobutyric acid:proton symporter" EXACT [] xref: GO:0005331 xref: GO:0015329 xref: GO:0015495 is_a: CCO:F0001533 ! hydrogen:amino acid symporter activity is_a: CCO:F0002659 ! L-gamma-aminobutyric acid transmembrane transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0002891 name: putrescine:ornithine antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out)." [TC:2.A.3.2.1] subset: gosubset_prok synonym: "putrescine-ornithine antiporter activity" EXACT [] synonym: "putrescine/ornithine antiporter activity" EXACT [] synonym: "putrescine:hydrogen symporter" EXACT [] xref: GO:0015496 is_a: CCO:F0000017 ! L-ornithine transmembrane transporter activity is_a: CCO:F0002749 ! solute:solute antiporter activity is_a: CCO:F0002884 ! putrescine transmembrane transporter activity [Term] id: CCO:F0002892 name: cadaverine:lysine antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cadaverine(out) + lysine(in) = cadaverine(in) + lysine(out)." [TC:2.A.3.2.2] subset: gosubset_prok xref: GO:0015497 is_a: CCO:F0002663 ! L-lysine transmembrane transporter activity is_a: CCO:F0002749 ! solute:solute antiporter activity is_a: CCO:F0002885 ! cadaverine transmembrane transporter activity [Term] id: CCO:F0002893 name: pantothenate:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in)." [TC:2.A.21.1.1] subset: gosubset_prok xref: GO:0015498 is_a: CCO:F0002703 ! pantothenate transporter activity is_a: CCO:F0002797 ! solute:sodium symporter activity [Term] id: CCO:F0002894 name: formate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of formate from one side of the membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid." [GOC:ai] subset: gosubset_prok xref: GO:0015499 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002895 name: glutamate:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in)." [TC:2.A.27.1.1] synonym: "sodium/excitatory glutamate cotransporter activity" EXACT [] synonym: "sodium/excitatory glutamate symporter activity" EXACT [] xref: GO:0008027 xref: GO:0015501 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0001552 ! L-glutamate transmembrane transporter activity [Term] id: CCO:F0002896 name: glutathione-regulated potassium exporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state." [PMID:11053405, TC:2.A.37.1.1, TC:2.A.37.1.2] subset: gosubset_prok xref: GO:0015503 is_a: CCO:F0002560 ! potassium ion transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002897 name: cytosine:hydrogen ion symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in)." [TC:2.A.39.1.1] synonym: "cytosine permease activity" RELATED [] xref: GO:0015504 is_a: CCO:F0002680 ! cytosine transmembrane transporter activity is_a: CCO:F0002815 ! nucleobase:cation symporter activity [Term] id: CCO:F0002898 name: uracil:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in)." [GOC:mtg_transport] subset: gosubset_prok synonym: "uracil permease activity" RELATED [] xref: GO:0015505 is_a: CCO:F0002681 ! uracil transmembrane transporter activity is_a: CCO:F0002815 ! nucleobase:cation symporter activity [Term] id: CCO:F0002899 name: nucleoside:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in)." [TC:2.A.1.10.1, TC:2.A.41.1.1] synonym: "nucleoside permease activity" RELATED [] synonym: "nucleoside:hydrogen ion symporter activity" EXACT [] synonym: "nucleoside:proton symporter" EXACT [] xref: GO:0015506 xref: GO:0015536 is_a: CCO:F0001567 ! nucleoside transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity [Term] id: CCO:F0002900 name: nitrite uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nitrite from the outside of a cell to the inside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "nitrite uptake permease activity" EXACT [] xref: GO:0015513 is_a: CCO:F0002591 ! nitrite transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0002943 ! uptake transmembrane transporter activity [Term] id: CCO:F0002901 name: nitrite efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "nitrite extrusion permease activity" EXACT [] xref: GO:0015514 is_a: CCO:F0002591 ! nitrite transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity [Term] id: CCO:F0002902 name: citrate:succinate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out)." [TC:2.A.47.3.2] subset: gosubset_prok xref: GO:0015515 is_a: CCO:F0002614 ! citrate transmembrane transporter activity is_a: CCO:F0002618 ! succinate transmembrane transporter activity is_a: CCO:F0002750 ! anion:anion antiporter activity [Term] id: CCO:F0002903 name: tartrate:succinate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out)." [TC:2.A.47.3.3] xref: GO:0015516 is_a: CCO:F0002618 ! succinate transmembrane transporter activity is_a: CCO:F0002750 ! anion:anion antiporter activity is_a: CCO:F0002935 ! tartrate transmembrane transporter activity [Term] id: CCO:F0002904 name: galactose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in)." [TC:2.A.1.1.1, TC:2.A.1.1.9] subset: gosubset_prok synonym: "galactose:proton symporter" EXACT [] synonym: "lactose, galactose:hydrogen symporter activity" BROAD [] xref: GO:0015517 is_a: CCO:F0001580 ! galactose transmembrane transporter activity is_a: CCO:F0002404 ! hexose:hydrogen symporter activity [Term] id: CCO:F0002905 name: arabinose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in)." [TC:2.A.1.1.2] synonym: "arabinose:proton symporter" EXACT [] xref: GO:0015518 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0005736 ! arabinose transmembrane transporter activity [Term] id: CCO:F0002906 name: D-xylose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in)." [TC:2.A.1.1.3] subset: gosubset_prok synonym: "D-xylose:proton symporter" EXACT [] xref: GO:0015519 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002625 ! D-xylose transmembrane transporter activity [Term] id: CCO:F0002907 name: tetracycline:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out)." [TC:2.A.1.2.4] subset: gosubset_prok synonym: "tetracyclin:hydrogen antiporter activity" EXACT [] synonym: "tetracyclin:proton antiporter activity" EXACT [] synonym: "tetracycline:proton antiporter" EXACT [] xref: GO:0015520 is_a: CCO:F0001951 ! tetracycline transporter activity is_a: CCO:F0002753 ! drug:hydrogen antiporter activity [Term] id: CCO:F0002908 name: hydrophobic uncoupler:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS." [TC:2.A.1.2.9] synonym: "hydrophobic uncoupler:proton antiporter" EXACT [] xref: GO:0015522 is_a: CCO:F0002753 ! drug:hydrogen antiporter activity is_a: CCO:F0003549 ! oxidative phosphorylation uncoupler activity [Term] id: CCO:F0002909 name: arabinose efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of arabinose from the inside of the cell to the outside of the cell across a membrane: H+(out) + arabinose(in) = H+(in) + arabinose(out)." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.1.2.14] synonym: "arabinose efflux permease activity" EXACT [] xref: GO:0015523 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity is_a: CCO:F0005736 ! arabinose transmembrane transporter activity [Term] id: CCO:F0002910 name: hexose-phosphate:inorganic phosphate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out)." [TC:2.A.1.4.1] xref: GO:0015526 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002597 ! hexose phosphate transmembrane transporter activity is_a: CCO:F0002761 ! organophosphate:inorganic phosphate antiporter activity [Term] id: CCO:F0002911 name: glycerol-phosphate:inorganic phosphate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out)." [TC:2.A.1.4.3] xref: GO:0015527 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002646 ! glycerol-3-phosphate transmembrane transporter activity is_a: CCO:F0002761 ! organophosphate:inorganic phosphate antiporter activity [Term] id: CCO:F0002912 name: lactose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in)." [TC:2.A.1.1.9, TC:2.A.1.5.1] synonym: "lactose, galactose:hydrogen symporter activity" BROAD [] synonym: "lactose:proton symporter" EXACT [] xref: GO:0015528 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002632 ! lactose transmembrane transporter activity [Term] id: CCO:F0002913 name: raffinose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in)." [TC:2.A.1.5.2] synonym: "raffinose:proton symporter" EXACT [] xref: GO:0015529 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002635 ! raffinose transmembrane transporter activity [Term] id: CCO:F0002914 name: shikimate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of shikimate from one side of the membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids." [GOC:ai] subset: gosubset_prok xref: GO:0015530 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002915 name: citrate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in)." [TC:2.A.1.6.1] synonym: "citrate:proton symporter" EXACT [] xref: GO:0015531 is_a: CCO:F0002614 ! citrate transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity [Term] id: CCO:F0002916 name: alpha-ketoglutarate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in)." [TC:2.A.1.6.2] subset: gosubset_prok synonym: "2-oxoglutarate:hydrogen symporter activity" EXACT [] synonym: "2-oxoglutarate:proton symporter" EXACT [] synonym: "alpha-ketoglutarate:proton symporter" EXACT [] xref: GO:0015532 is_a: CCO:F0002616 ! alpha-ketoglutarate transmembrane transporter activity is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0002917 name: shikimate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in)." [TC:2.A.1.6.6] synonym: "shikimate:proton symporter" EXACT [] xref: GO:0015533 is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002745 ! anion:cation symporter activity is_a: CCO:F0002914 ! shikimate transmembrane transporter activity [Term] id: CCO:F0002918 name: fucose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in)." [TC:2.A.1.7.1] synonym: "fucose:proton symporter" EXACT [] xref: GO:0015535 is_a: CCO:F0002404 ! hexose:hydrogen symporter activity is_a: CCO:F0002627 ! fucose transmembrane transporter activity [Term] id: CCO:F0002919 name: xanthosine:hydrogen ion symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in)." [TC:2.A.1.10.2] synonym: "xanthosine permease activity" RELATED [] xref: GO:0015537 is_a: CCO:F0002899 ! nucleoside:hydrogen symporter activity is_a: CCO:F0002934 ! xanthosine transmembrane transporter activity [Term] id: CCO:F0002920 name: sialic acid:hydrogen ion symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in)." [TC:2.A.1.12.1] subset: gosubset_prok synonym: "sialic acid permease activity" RELATED [] xref: GO:0015538 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002613 ! sialic acid transmembrane transporter activity [Term] id: CCO:F0002921 name: hexuronate:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate." [TC:2.A.1.14.2] synonym: "hexuronate (glucuronate/galacturonate) porter activity" NARROW [] synonym: "hexuronate porter activity" RELATED [] xref: GO:0015539 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002611 ! hexuronate transmembrane transporter activity [Term] id: CCO:F0002922 name: 3-hydroxyphenyl propionate:hydrogen ion symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in)." [TC:2.A.1.15.2] synonym: "3-hydroxyphenyl propionate porter activity" RELATED [] xref: GO:0015540 is_a: CCO:F0002742 ! symporter activity is_a: CCO:F0002932 ! 3-hydroxyphenyl propanoate transmembrane transporter activity [Term] id: CCO:F0002923 name: secondary active cyanate uptake transmembrane transporter namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cyanate(out) = cyanate(in)." [TC:2.A.1.17.1] synonym: "cyanate porter activity" RELATED [] xref: GO:0015541 is_a: CCO:F0002588 ! cyanate transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002924 name: sugar efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(in) = sugar(out)." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.1.20.1] subset: gosubset_prok synonym: "lactose/glucose efflux transporter activity" NARROW [] xref: GO:0015542 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity [Term] id: CCO:F0002925 name: phenyl propionate uptake uniporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenyl propionate(out) = phenyl propionate(in)." [GOC:mtg_transport, TC:2.A.1.27.1] synonym: "phenyl propionate permease activity" RELATED [] xref: GO:0015544 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity is_a: CCO:F0002933 ! propionate transmembrane transporter activity [Term] id: CCO:F0002926 name: bicyclomycin transporter activity namespace: molecular_function def: "Enables the directed movement of bicyclomycin into, out of, within or between cells. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive." [ISBN:91191028X] subset: gosubset_prok synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" NARROW [] xref: GO:0015545 is_a: CCO:F0005732 ! antibiotic transporter activity [Term] id: CCO:F0002927 name: sulfathiazole transporter activity namespace: molecular_function def: "Enables the directed movement of sulfathiazole into, out of, within or between cells. Sulfathiazole is an antibacterial agent of the sulfonamide group." [http://cancerweb.ncl.ac.uk/] synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" NARROW [] synonym: "sulphathiazole transporter activity" EXACT [] xref: GO:0015546 is_a: CCO:F0006070 ! azole transporter activity [Term] id: CCO:F0002928 name: nalidixic acid transporter activity namespace: molecular_function def: "Enables the directed movement of nalidixic acid into, out of, within or between cells. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication." [http://cancerweb.ncl.ac.uk/] synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" NARROW [] xref: GO:0015547 is_a: CCO:F0005732 ! antibiotic transporter activity is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0002929 name: organomercurial transporter activity namespace: molecular_function def: "Enables the directed movement of organomercurial compounds into, out of, within or between cells. Organomercurial substances are any organic compound containing a mercury atom." [GOC:ai] synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" NARROW [] xref: GO:0015548 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0002930 name: carbonyl cyanide m-chlorophenylhydrazone transporter activity namespace: molecular_function def: "Enables the directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of, within or between cells. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes." [http://cancerweb.ncl.ac.uk/] synonym: "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity" NARROW [] synonym: "CCCP transporter" EXACT [] xref: GO:0015549 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0002931 name: galacturonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of galacturonate from one side of the membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:ai] xref: GO:0015550 is_a: CCO:F0002611 ! hexuronate transmembrane transporter activity [Term] id: CCO:F0002932 name: 3-hydroxyphenyl propanoate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of 3-hydroxyphenyl propanoate from one side of the membrane to the other." [GOC:ai] synonym: "3-hydroxyphenyl propionate transmembrane transporter activity" EXACT [] xref: GO:0015551 is_a: CCO:F0002933 ! propionate transmembrane transporter activity [Term] id: CCO:F0002933 name: propionate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of propionate from one side of the membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH." [GOC:ai] xref: GO:0015552 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002934 name: xanthosine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015553 is_a: CCO:F0002682 ! purine nucleoside transmembrane transporter activity [Term] id: CCO:F0002935 name: tartrate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of tartrate from one side of the membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria." [GOC:ai] subset: gosubset_prok xref: GO:0015554 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002936 name: acriflavin resistant pump activity namespace: molecular_function xref: GO:0015555 is_a: CCO:F0002946 ! acriflavin transporter activity [Term] id: CCO:F0002937 name: C4-dicarboxylate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of C4-dicarboxylate from one side of the membrane to the other." [GOC:krc] subset: gosubset_prok xref: GO:0015556 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002938 name: arginine targeting transmembrane transporter activity namespace: molecular_function xref: GO:0015557 is_a: CCO:F0001997 ! protein transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0002939 name: p-aminobenzoyl-glutamate uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of p-aminobenzoyl-glutamate from the outside of a cell to the inside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "p-aminobenzoyl-glutamate uptake permease activity" EXACT [] xref: GO:0015558 is_a: CCO:F0002943 ! uptake transmembrane transporter activity is_a: CCO:F0002949 ! p-aminobenzoyl-glutamate transmembrane transporter activity [Term] id: CCO:F0002940 name: multidrug efflux pump activity namespace: molecular_function subset: gosubset_prok xref: GO:0015559 is_a: CCO:F0002707 ! multidrug transporter activity [Term] id: CCO:F0002941 name: rhamnose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in)." [TC:2.A.7.6.1] synonym: "rhamnose:proton symporter" EXACT [] xref: GO:0015561 is_a: CCO:F0002404 ! hexose:hydrogen symporter activity is_a: CCO:F0002630 ! rhamnose transmembrane transporter activity [Term] id: CCO:F0002942 name: efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "efflux permease activity" EXACT [] synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" NARROW [] xref: GO:0015562 is_a: CCO:F0004284 ! transmembrane transporter activity [Term] id: CCO:F0002943 name: uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a specific substance or related group of substances from the outside of a cell to the inside across a membrane." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "cobalt, zinc uptake permease activity" NARROW [] synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" NARROW [] synonym: "uptake permease activity" RELATED [] synonym: "zinc, cadmium uptake permease activity" NARROW [] synonym: "zinc, iron permease activity" NARROW [] xref: GO:0015563 is_a: CCO:F0004284 ! transmembrane transporter activity [Term] id: CCO:F0002944 name: multidrug, alkane resistant pump activity namespace: molecular_function xref: GO:0015564 is_a: CCO:F0002707 ! multidrug transporter activity is_a: CCO:F0002947 ! alkane transporter activity [Term] id: CCO:F0002945 name: threonine efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of threonine from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "threonine efflux permease activity" EXACT [] synonym: "threonine export protein" RELATED [] synonym: "threonine export transporter activity" EXACT [] xref: GO:0015565 is_a: CCO:F0002669 ! L-threonine transmembrane transporter activity is_a: CCO:F0008481 ! L-amino acid efflux transmembrane transporter activity [Term] id: CCO:F0002946 name: acriflavin transporter activity namespace: molecular_function def: "Enables the directed movement of acriflavin into, out of, within or between cells. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication." [http://cancerweb.ncl.ac.uk/] xref: GO:0015566 is_a: CCO:F0002706 ! drug transporter activity is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0002947 name: alkane transporter activity namespace: molecular_function def: "Enables the directed movement of alkanes into, out of, within or between cells. Alkanes are saturated aliphatic hydrocarbon compounds." [GOC:ai] xref: GO:0015567 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0002948 name: L-idonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-idonate from one side of the membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose." [GOC:ai] subset: gosubset_prok synonym: "L-idonate/D-gluconate:hydrogen symporter activity" NARROW [] xref: GO:0015568 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0002949 name: p-aminobenzoyl-glutamate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid." [GOC:ai] subset: gosubset_prok synonym: "p-aminobenzoyl-glutamate transporter activity" BROAD [] xref: GO:0015569 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0002950 name: energizer of outer membrane receptor-mediated transport activity namespace: molecular_function xref: GO:0015570 is_a: CCO:F0002825 ! ion-gradient-driven energizer activity [Term] id: CCO:F0002951 name: N-acetylgalactosamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of N-acetylgalactosamine from one side of the membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "N-acetylgalactosamine permease activity" EXACT [] xref: GO:0015571 xref: GO:0015590 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002952 name: N-acetylglucosamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of N-acetylglucosamine from one side of the membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide moiety of a glycoprotein." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "D-GlcNAc transmembrane transporter activity" EXACT [] synonym: "N-Acetyl-D-glucosamine permease" RELATED [] synonym: "N-acetyl-D-glucosamine transmembrane transporter activity" EXACT [] synonym: "N-acetylchitosamine transmembrane transporter activity" EXACT [] synonym: "N-acetylglucosamine permease activity" RELATED [] xref: GO:0015572 xref: GO:0015580 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002953 name: beta-glucoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of beta-glucosides from one side of the membrane to the other. Beta-glucosides are glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in a beta configuration." [GOC:jl, GOC:mtg_transport, http://www.biochem.purdue.edu/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "beta-glucoside permease activity" EXACT [] xref: GO:0015573 xref: GO:0015582 is_a: CCO:F0005760 ! glucoside transmembrane transporter activity [Term] id: CCO:F0002954 name: trehalose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of trehalose from one side of the membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "trehalose permease activity" EXACT [] xref: GO:0015574 xref: GO:0015584 is_a: CCO:F0002628 ! alpha-glucoside transmembrane transporter activity is_a: CCO:F0002631 ! disaccharide transmembrane transporter activity [Term] id: CCO:F0002955 name: mannitol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of mannitol from one side of the membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "mannitol permease activity" EXACT [] xref: GO:0015575 xref: GO:0015586 is_a: CCO:F0002643 ! polyol transmembrane transporter activity [Term] id: CCO:F0002956 name: sorbitol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sorbitol from one side of the membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "glucitol permease activity" EXACT [] synonym: "glucitol transporter activity" EXACT [] synonym: "sorbitol permease activity" EXACT [] xref: GO:0015576 xref: GO:0015587 is_a: CCO:F0002643 ! polyol transmembrane transporter activity [Term] id: CCO:F0002957 name: galactitol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a galactitol from one side of the membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "galactitol permease activity" EXACT [] xref: GO:0015577 xref: GO:0015588 is_a: CCO:F0002643 ! polyol transmembrane transporter activity [Term] id: CCO:F0002958 name: mannose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of mannose from one side of the membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "mannose permease activity" EXACT [] xref: GO:0015578 xref: GO:0015589 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002959 name: D-ribose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-ribose from one side of the membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose moiety of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok xref: GO:0015591 is_a: CCO:F0002623 ! pentose transmembrane transporter activity [Term] id: CCO:F0002960 name: methylgalactoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of methylgalactoside from one side of the membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group." [GOC:mtg_transport, http://cancerweb.ncl.ac.uk/, ISBN:0815340729] subset: gosubset_prok synonym: "galactose/glucose (methylgalactoside) porter activity" NARROW [] xref: GO:0015592 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002961 name: allose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of allose from one side of the membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0015593 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0002962 name: putrescine-importing ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + putrescine(out) = ADP + phosphate + putrescine(in)." [EC:3.6.3.31] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "putrescine porter activity" BROAD [] xref: GO:0015594 is_a: CCO:F0002836 ! polyamine-transporting ATPase activity is_a: CCO:F0002884 ! putrescine transmembrane transporter activity [Term] id: CCO:F0002963 name: spermidine-importing ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + spermidine(out) = ADP + phosphate + spermidine(in)." [EC:3.6.3.31] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "spermidine porter activity" BROAD [] xref: GO:0015595 is_a: CCO:F0002836 ! polyamine-transporting ATPase activity is_a: CCO:F0002969 ! spermidine transmembrane transporter activity [Term] id: CCO:F0002964 name: arginine-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arginine(out) = ADP + phosphate + arginine(in)." [EC:3.6.3.21] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "arginine porter activity" EXACT [] xref: GO:0015598 is_a: CCO:F0002655 ! arginine transmembrane transporter activity is_a: CCO:F0002845 ! polar-amino acid-transporting ATPase activity [Term] id: CCO:F0002965 name: glutamine-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) = ADP + phosphate + glutamine(in)." [EC:3.6.3.21] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "glutamine porter activity" BROAD [] xref: GO:0015599 is_a: CCO:F0002660 ! L-glutamine transmembrane transporter activity is_a: CCO:F0002845 ! polar-amino acid-transporting ATPase activity [Term] id: CCO:F0002966 name: iron chelate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions." [http://www.onelook.com] subset: gosubset_prok xref: GO:0015603 is_a: CCO:F0001599 ! iron ion transmembrane transporter activity [Term] id: CCO:F0002967 name: phosphonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of phosphonate from one side of a membrane to the other. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)." [GOC:ai] subset: gosubset_prok xref: GO:0015604 is_a: CCO:F0001967 ! organic anion transmembrane transporter activity [Term] id: CCO:F0002968 name: organophosphate ester transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds." [GOC:mcc] xref: GO:0015605 is_a: CCO:F0001967 ! organic anion transmembrane transporter activity [Term] id: CCO:F0002969 name: spermidine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of the membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015606 is_a: CCO:F0002675 ! polyamine transmembrane transporter activity [Term] id: CCO:F0002970 name: fatty acyl CoA transporter activity namespace: molecular_function def: "Enables the directed movement of a fatty acyl CoA group into, out of, within or between cells. A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A moiety attached to it." [GOC:ai] xref: GO:0015607 is_a: CCO:F0002714 ! fatty acyl transporter activity [Term] id: CCO:F0002971 name: carbohydrate-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) = ADP + phosphate + carbohydrate(in)." [GOC:ai, TC:3.A.1.1.-, TC:3.A.1.2.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "carbohydrate uptake transporter activity" EXACT [] synonym: "sugar transporter" NARROW [] xref: GO:0015608 is_a: CCO:F0005819 ! carbohydrate-transporting ATPase activity [Term] id: CCO:F0002972 name: maltooligosaccharide-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltooligosaccharide(out) = ADP + phosphate + maltooligosaccharide(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "maltooligosaccharide porter activity" BROAD [] xref: GO:0015609 is_a: CCO:F0002634 ! oligosaccharide transmembrane transporter activity is_a: CCO:F0002971 ! carbohydrate-importing ATPase activity [Term] id: CCO:F0002973 name: glycerol phosphate-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-phosphate(out) = ADP + phosphate + glycerol-phosphate(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "glycerol-phosphate porter activity" BROAD [] xref: GO:0015610 is_a: CCO:F0002646 ! glycerol-3-phosphate transmembrane transporter activity is_a: CCO:F0002971 ! carbohydrate-importing ATPase activity [Term] id: CCO:F0002974 name: D-ribose-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) = ADP + phosphate + D-ribose(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "D-ribose porter activity" BROAD [] xref: GO:0015611 is_a: CCO:F0002827 ! monosaccharide-transporting ATPase activity is_a: CCO:F0002959 ! D-ribose transmembrane transporter activity [Term] id: CCO:F0002975 name: L-arabinose-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) = ADP + phosphate + L-arabinose(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "L-arabinose porter activity" EXACT [] xref: GO:0015612 is_a: CCO:F0002624 ! L-arabinose transmembrane transporter activity is_a: CCO:F0002827 ! monosaccharide-transporting ATPase activity [Term] id: CCO:F0002976 name: D-xylose-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) = ADP + phosphate + D-xylose(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "D-xylose porter activity" BROAD [] xref: GO:0015614 is_a: CCO:F0002625 ! D-xylose transmembrane transporter activity is_a: CCO:F0002827 ! monosaccharide-transporting ATPase activity [Term] id: CCO:F0002977 name: D-allose-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) = ADP + phosphate + D-allose(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "D-allose porter activity" BROAD [] xref: GO:0015615 is_a: CCO:F0002961 ! allose transmembrane transporter activity is_a: CCO:F0002971 ! carbohydrate-importing ATPase activity [Term] id: CCO:F0002978 name: DNA translocase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive movement along a single- or double-stranded DNA molecule." [GOC:mah, PMID:16428451, PMID:17631491] comment: Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane. xref: GO:0015616 is_a: CCO:F0000274 ! DNA binding is_a: CCO:F0001707 ! DNA-dependent ATPase activity [Term] id: CCO:F0002979 name: thiamin pyrophosphate-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamin pyrophosphate(out) = ADP + phosphate + thiamin pyrophosphate(in)." [TC:3.A.1.19.1] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "thiamin pyrophosphate ABC transporter" NARROW [] synonym: "thiamin pyrophosphate porter activity" BROAD [] synonym: "thiamine pyrophosphate transporting ATPase activity" EXACT [] synonym: "TPP transporting ATPase activity" EXACT [] xref: GO:0015619 is_a: CCO:F0002704 ! thiamin transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002980 name: ferric-enterobactin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ferric-enterobactin from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015620 is_a: CCO:F0002777 ! siderophore-iron transmembrane transporter activity [Term] id: CCO:F0002981 name: ferric triacetylfusarinine C transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ferric triacetylfusarinine C from one side of a membrane to the other." [GOC:ai] xref: GO:0015621 is_a: CCO:F0002571 ! ferric iron transmembrane transporter activity [Term] id: CCO:F0002982 name: ferric-hydroxamate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ferric-hydroxamate from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015622 is_a: CCO:F0002777 ! siderophore-iron transmembrane transporter activity [Term] id: CCO:F0002983 name: iron-chelate-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + iron chelate(out) = ADP + phosphate + iron chelate(in). Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores are imported." [EC:3.6.3.34] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (iron-chelate-importing)" EXACT [EC:3.6.3.34] synonym: "ferric/ferric-dicitrate porter" BROAD [] synonym: "iron-chelate ABC transporter" NARROW [] xref: EC:3.6.3.34 xref: GO:0015409 xref: GO:0015623 xref: MetaCyc:3.6.3.34-RXN is_a: CCO:F0002966 ! iron chelate transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0002984 name: ferric-enterobactin-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ferric-enterobactin ABC transporter" NARROW [] synonym: "ferric-enterobactin porter activity" BROAD [] xref: GO:0015624 is_a: CCO:F0002980 ! ferric-enterobactin transmembrane transporter activity is_a: CCO:F0002983 ! iron-chelate-transporting ATPase activity [Term] id: CCO:F0002985 name: ferric-hydroxamate-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in)." [TC:3.A.1.-.-] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ferric-hydroxamate ABC transporter" NARROW [] synonym: "ferric-hydroxamate porter activity" BROAD [] xref: GO:0015625 is_a: CCO:F0002982 ! ferric-hydroxamate transmembrane transporter activity is_a: CCO:F0002983 ! iron-chelate-transporting ATPase activity [Term] id: CCO:F0002986 name: L-diaminopimelate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the levorotatory isomer anion of 2,6-diaminoheptanedioic acid." [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] synonym: "cystine/diaminopimelate porter activity" NARROW [] synonym: "L-diaminopimelate transporter activity" BROAD [] xref: GO:0015626 is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0002987 name: tubulin binding namespace: molecular_function def: "Interacting selectively with monomeric or multimeric forms of tubulin, including microtubules." [GOC:clt] xref: GO:0015631 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0002988 name: zinc transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in)." [TC:3.A.1.-.-] synonym: "zinc porter activity" RELATED [] xref: GO:0015633 is_a: CCO:F0001601 ! zinc ion transmembrane transporter activity [Term] id: CCO:F0002989 name: lipopolysaccharide exporter activity namespace: molecular_function def: "Catalysis of the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide." [GOC:mtg_transport, ISBN:0815340729] synonym: "LPS exporter activity" EXACT [] xref: GO:0015634 is_a: CCO:F0002692 ! lipopolysaccharide transmembrane transporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity [Term] id: CCO:F0002990 name: short-chain fatty acid transporter activity namespace: molecular_function def: "Enables the directed movement of short-chain fatty acids into, out of, within or between cells. Short-chain fatty acids have a chain length of less than 8 carbons." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015635 is_a: CCO:F0002713 ! fatty acid transporter activity [Term] id: CCO:F0002991 name: short-chain fatty acid uptake transporter activity namespace: molecular_function xref: GO:0015636 is_a: CCO:F0002990 ! short-chain fatty acid transporter activity [Term] id: CCO:F0002992 name: microcin uptake permease activity namespace: molecular_function subset: gosubset_prok xref: GO:0015638 is_a: CCO:F0002671 ! peptide transporter activity is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0002993 name: ferrous iron uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) + energy = Fe2+(in)." [TC:9.A.8.1.1] subset: gosubset_prok xref: GO:0015639 is_a: CCO:F0002573 ! ferrous iron transmembrane transporter activity [Term] id: CCO:F0002994 name: peptidoglycan peptide transporter activity namespace: molecular_function def: "Enables the directed movement of peptidoglycan peptides into, out of, within or between cells. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains." [http://cancerweb.ncl.ac.uk/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "murein peptide transporter activity" EXACT [] synonym: "muropeptide transporter activity" EXACT [] xref: GO:0015640 is_a: CCO:F0002671 ! peptide transporter activity is_a: CCO:F0002997 ! peptidoglycan transporter activity [Term] id: CCO:F0002995 name: toxin binding namespace: molecular_function def: "Interacting selectively with a toxin, a poisonous substance that causes damage to biological systems. Toxins are differentiated from simple chemical poisons and vegetable alkaloids by their high molecular weight and antigenicity (they elicit an antibody response)." [GOC:ai, http://cancerweb.ncl.ac.uk/] synonym: "antitoxin activity" RELATED [] synonym: "lipoprotein antitoxin" RELATED [] xref: GO:0015643 is_a: CCO:F0000342 ! antigen binding [Term] id: CCO:F0002996 name: fatty-acid ligase activity namespace: molecular_function def: "Catalysis of the ligation of a long-chain carboxylic acid to an acceptor, coupled to the hydrolysis of ATP." [EC:6.2.1.20, EC:6.2.1.3, GOC:mah] subset: gosubset_prok synonym: "acid:CoA ligase (AMP-forming) activity" EXACT [EC:6.2.1.3] synonym: "acyl coenzyme A synthetase activity" EXACT [EC:6.2.1.3] synonym: "acyl-coenzyme A ligase activity" EXACT [EC:6.2.1.3] synonym: "fatty acid CoA ligase activity" EXACT [EC:6.2.1.3] synonym: "fatty acyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.3] xref: EC:6.2.1.- xref: GO:0015645 is_a: CCO:F0003436 ! ligase activity, forming carbon-sulfur bonds [Term] id: CCO:F0002997 name: peptidoglycan transporter activity namespace: molecular_function def: "Enables the directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of, within or between cells." [GOC:ai] subset: gosubset_prok synonym: "murein transporter activity" EXACT [] xref: GO:0015647 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0002998 name: lipid-linked peptidoglycan transporter activity namespace: molecular_function synonym: "lipid-linked murein transporter activity" EXACT [] xref: GO:0015648 is_a: CCO:F0002997 ! peptidoglycan transporter activity [Term] id: CCO:F0002999 name: 2-keto-3-deoxygluconate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in)." [TC:2.A.10.1.1] subset: gosubset_prok synonym: "2-keto-3-deoxygluconate:proton symporter" EXACT [] xref: GO:0015649 is_a: CCO:F0001605 ! cation:sugar symporter activity is_a: CCO:F0002605 ! gluconate transmembrane transporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0003000 name: lactate:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in)." [TC:2.A.14.1.1] synonym: "lactate permease" BROAD [] synonym: "lactate:hydrogen porter activity" EXACT [] synonym: "lactate:proton porter" EXACT [] xref: GO:0015650 is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0003001 name: quaternary ammonium group transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "quaternary amine transmembrane transporter activity" EXACT [] synonym: "quaternary ammonium compound transporter activity" EXACT [] xref: GO:0015202 xref: GO:0015651 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0002580 ! organic cation transmembrane transporter activity is_a: CCO:F0004309 ! inorganic cation transmembrane transporter activity [Term] id: CCO:F0003002 name: quaternary ammonium group:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in)." [GOC:ai] subset: gosubset_prok synonym: "quaternary ammonium group:proton symporter" EXACT [] xref: GO:0015652 is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0003001 ! quaternary ammonium group transmembrane transporter activity [Term] id: CCO:F0003003 name: glycine betaine:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in)." [TC:2.A.15.1.1] subset: gosubset_prok synonym: "glycine betaine:proton symporter" EXACT [] xref: GO:0015653 is_a: CCO:F0003002 ! quaternary ammonium group:hydrogen symporter activity [Term] id: CCO:F0003004 name: tellurite uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of tellurite from the outside of a cell to the inside across a membrane: tellurite(out) + H+(out) = tellurite(in) + H+(in)." [GOC:mtg_transport, ISBN:0815340729, TC:2.A.16.1.1] synonym: "tellurite-resistance uptake permease activity" EXACT [] synonym: "tellurite-resistance uptake transmembrane transporter activity" EXACT [] xref: GO:0015654 is_a: CCO:F0002943 ! uptake transmembrane transporter activity [Term] id: CCO:F0003005 name: alanine:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in)." [GOC:ai] subset: gosubset_prok xref: GO:0015655 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0001541 ! neutral L-amino acid secondary active transmembrane transporter activity [Term] id: CCO:F0003006 name: branched-chain amino acid:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in)." [TC:2.A.26.1.1] xref: GO:0015657 is_a: CCO:F0001534 ! sodium:amino acid symporter activity is_a: CCO:F0003007 ! branched-chain aliphatic amino acid transmembrane transporter activity [Term] id: CCO:F0003007 name: branched-chain aliphatic amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of branched-chain aliphatic amino acids from one side of a membrane to the other. Branched-chain aliphatic amino acids are amino acids with a branched carbon skeleton without rings." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "branched-chain aliphatic amino acid transporter activity" BROAD [] synonym: "leucine/valine/isoleucine permease activity" RELATED [] synonym: "valine/tyrosine/tryptophan permease activity" RELATED [] xref: GO:0015658 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0003008 name: formate uptake transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of formate from the outside of a cell to the inside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "formate uptake permease activity" EXACT [] xref: GO:0015659 is_a: CCO:F0002894 ! formate transmembrane transporter activity is_a: CCO:F0002943 ! uptake transmembrane transporter activity [Term] id: CCO:F0003009 name: formate efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of formate from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "formate efflux permease activity" EXACT [] xref: GO:0015509 xref: GO:0015660 is_a: CCO:F0002894 ! formate transmembrane transporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity [Term] id: CCO:F0003010 name: L-lysine efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "L-lysine exporter activity" EXACT [] synonym: "L-lysine, 2,6-diaminohexanoic acid efflux transmembrane transporter activity" EXACT [] xref: GO:0015661 is_a: CCO:F0002663 ! L-lysine transmembrane transporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity [Term] id: CCO:F0003011 name: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate." [PMID:10322420, PMID:10600683] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "P-type ATPase activity" EXACT [] synonym: "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity" NARROW [] xref: GO:0015662 is_a: CCO:F0005698 ! ATPase activity, coupled to transmembrane movement of ions [Term] id: CCO:F0003012 name: nicotinamide mononucleotide transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of nicotinamide mononucleotide into, out of, within or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP." [http://cancerweb.ncl.ac.uk/, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok synonym: "nicotinamide mononucleotide permease activity" RELATED [] synonym: "nicotinamide ribonucleotide transmembrane transporter activity" EXACT [] xref: GO:0015663 xref: GO:0015664 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0003013 name: alcohol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an alcohol from one side of the membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0015665 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0003014 name: restriction endodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks." [GOC:mlg] subset: gosubset_prok synonym: "restriction endonuclease activity" EXACT [] synonym: "restriction enzyme activity" EXACT [] xref: GO:0015666 is_a: CCO:F0000917 ! endodeoxyribonuclease activity [Term] id: CCO:F0003015 name: site-specific DNA-methyltransferase (cytosine-N4-specific) activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine." [EC:2.1.1.113] subset: gosubset_prok synonym: "DNA[cytosine-N4]methyltransferase activity" EXACT [EC:2.1.1.113] synonym: "m4C-forming MTase activity" EXACT [EC:2.1.1.113] synonym: "modification methylase activity" RELATED [EC:2.1.1.113] synonym: "N(4)-cytosine-specific DNA methylase activity" EXACT [EC:2.1.1.113] synonym: "N4-cytosine-specific DNA methylase activity" EXACT [EC:2.1.1.113] synonym: "restriction-modification system activity" RELATED [EC:2.1.1.113] synonym: "S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity" EXACT [EC:2.1.1.113] synonym: "S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity" EXACT [EC:2.1.1.113] xref: EC:2.1.1.113 xref: GO:0015667 xref: MetaCyc:2.1.1.113-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity is_a: CCO:F0002339 ! DNA-methyltransferase activity [Term] id: CCO:F0003016 name: Type III site-specific deoxyribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites." [EC:3.1.21.5, PMID:12654995] subset: gosubset_prok synonym: "Type III restriction enzyme activity" EXACT [] xref: EC:3.1.21.5 xref: GO:0015668 xref: MetaCyc:3.1.21.5-RXN is_a: CCO:F0003014 ! restriction endodeoxyribonuclease activity is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0003017 name: aspartate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2." [EC:1.4.3.1, EC:1.4.3.16] subset: gosubset_prok xref: EC:1.4.3.- xref: GO:0015922 is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0003018 name: mannosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative." [GOC:ai] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0015923 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003019 name: mannosyl-oligosaccharide mannosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides." [EC:3.2.1.-, GOC:ai] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0015924 is_a: CCO:F0003018 ! mannosidase activity [Term] id: CCO:F0003020 name: galactosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative." [GOC:ai] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0015925 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003021 name: glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0015926 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003022 name: trehalase activity namespace: molecular_function def: "Catalysis of the hydrolysis of trehalose or a trehalose derivative." [GOC:ai] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0015927 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003023 name: fucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative." [GOC:ai] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0015928 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003024 name: hexosaminidase activity namespace: molecular_function def: "Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides." [http://www.onelook.com/, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0015929 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003025 name: glutamate synthase activity namespace: molecular_function def: "Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors." [EC:1.4.-.-] subset: gosubset_prok xref: EC:1.4.-.- xref: GO:0015930 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0003026 name: nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok xref: GO:0015932 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0003027 name: sulfite reductase activity namespace: molecular_function def: "Catalysis of the reaction: H2S + acceptor + 3 H2O = SO3(2-) (sulfite) + reduced acceptor." [EC:1.8.99.1] subset: gosubset_prok synonym: "assimilatory sulfite reductase activity" EXACT [EC:1.8.99.1] synonym: "assimilatory-type sulfite reductase activity" EXACT [EC:1.8.99.1] synonym: "hydrogen-sulfide:(acceptor) oxidoreductase activity" EXACT [EC:1.8.99.1] synonym: "hydrogen-sulfide:acceptor oxidoreductase activity" EXACT [EC:1.8.99.1] synonym: "sulphite reductase activity" EXACT [] xref: EC:1.8.99.1 xref: GO:0016002 xref: MetaCyc:SULFITE-REDUCTASE-RXN is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003028 name: phospholipase activator activity namespace: molecular_function def: "Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid." [GOC:ai] xref: GO:0016004 is_a: CCO:F0008245 ! lipase activator activity [Term] id: CCO:F0003029 name: phospholipase A2 activator activity namespace: molecular_function def: "Increases the activity of the enzyme phospholipase A2." [GOC:ai] xref: GO:0016005 is_a: CCO:F0003028 ! phospholipase activator activity [Term] id: CCO:F0003030 name: morphogen activity namespace: molecular_function xref: GO:0016015 is_a: CCO:F0001225 ! signal transducer activity [Term] id: CCO:F0003031 name: cyclosporin A binding namespace: molecular_function def: "Interacting selectively with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids." [GOC:mb] synonym: "cyclophilin" RELATED [] xref: GO:0016018 is_a: CCO:F0001746 ! drug binding is_a: CCO:F0005639 ! peptide binding [Term] id: CCO:F0003032 name: peptidoglycan receptor activity namespace: molecular_function def: "Combining with a peptidoglycan to initiate a change in cell activity." [PMID:14698226] comment: Note that only peptidoglycan recognition proteins with receptor activity should be annotated to this term; otherwise use 'peptidoglycan binding ; GO:0042834' instead. synonym: "peptidoglycan recognition activity" NARROW [] xref: GO:0016019 is_a: CCO:F0001838 ! pattern recognition receptor activity is_a: CCO:F0005721 ! peptidoglycan binding [Term] id: CCO:F0003033 name: metarhodopsin binding namespace: molecular_function def: "Interacting selectively with metarhodopsin, a transient intermediate produced upon irradiation of rhodopsin in the visual cycle and existing in two forms, metarhodopsins I and II. The latter dissociates to form opsin and all-trans retinal." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0016030 is_a: CCO:F0000258 ! opsin binding [Term] id: CCO:F0003034 name: maleylacetoacetate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate." [EC:5.2.1.2] subset: gosubset_prok synonym: "4-maleylacetoacetate cis-trans-isomerase activity" EXACT [EC:5.2.1.2] synonym: "maleylacetoacetic isomerase activity" EXACT [EC:5.2.1.2] synonym: "maleylacetone cis-trans-isomerase activity" EXACT [EC:5.2.1.2] synonym: "maleylacetone isomerase activity" EXACT [EC:5.2.1.2] xref: EC:5.2.1.2 xref: GO:0016034 xref: GO:0018841 xref: MetaCyc:MALEYLACETOACETATE-ISOMERASE-RXN xref: Reactome:23371 xref: UM-BBD_enzymeID:e0082 is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0003035 name: glutamate synthase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: 2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+." [EC:1.4.1.14] subset: gosubset_prok synonym: "glutamate (reduced nicotinamide adenine dinucleotide) synthase" EXACT [EC:1.4.1.14] synonym: "L-glutamate synthase (NADH)" EXACT [EC:1.4.1.14] synonym: "L-glutamate synthase activity" BROAD [EC:1.4.1.14] synonym: "L-glutamate synthetase activity" BROAD [EC:1.4.1.14] synonym: "L-glutamate:NAD+ oxidoreductase (transaminating)" EXACT [EC:1.4.1.14] synonym: "NADH-dependent glutamate synthase activity" EXACT [EC:1.4.1.14] synonym: "NADH-glutamate synthase activity" EXACT [EC:1.4.1.14] synonym: "NADH: GOGAT" RELATED [EC:1.4.1.14] xref: EC:1.4.1.14 xref: GO:0016040 xref: MetaCyc:GLUTAMATE-SYNTHASE-(NADH)-RXN is_a: CCO:F0006093 ! glutamate synthase activity, NADH or NADPH as acceptor [Term] id: CCO:F0003036 name: glutamate synthase (ferredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin." [EC:1.4.7.1] subset: gosubset_prok synonym: "ferredoxin-dependent glutamate synthase activity" EXACT [EC:1.4.7.1] synonym: "ferredoxin-glutamate synthase activity" EXACT [EC:1.4.7.1] synonym: "glutamate synthase (ferredoxin-dependent)" EXACT [EC:1.4.7.1] synonym: "L-glutamate:ferredoxin oxidoreductase (transaminating)" EXACT [EC:1.4.7.1] xref: EC:1.4.7.1 xref: GO:0016041 xref: MetaCyc:GLUTAMATE-SYNTHASE-(FERREDOXIN)-RXN xref: MetaCyc:PWY-4341 is_a: CCO:F0003025 ! glutamate synthase activity is_a: CCO:F0003243 ! oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0003037 name: myostimulatory hormone activity namespace: molecular_function xref: GO:0016084 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0003038 name: myoinhibitory hormone activity namespace: molecular_function xref: GO:0016085 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0003039 name: ecdysiostatic hormone activity namespace: molecular_function xref: GO:0016087 is_a: CCO:F0001481 ! neuropeptide hormone activity [Term] id: CCO:F0003040 name: translation release factor activity, codon specific namespace: molecular_function def: "A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site." [ISBN:0198547684] subset: gosubset_prok xref: GO:0016149 is_a: CCO:F0000318 ! translation release factor activity [Term] id: CCO:F0003041 name: translation release factor activity, codon nonspecific namespace: molecular_function def: "A translation release factor that is not specific to particular codons; binds to guanine nucleotides." [ISBN:0198547684] comment: Consider also annotating to the molecular function term 'GTP binding ; GO:0005525'. xref: GO:0016150 is_a: CCO:F0000318 ! translation release factor activity [Term] id: CCO:F0003042 name: nickel ion binding namespace: molecular_function def: "Interacting selectively with nickel (Ni) ions." [GOC:ai] subset: gosubset_prok synonym: "nickel binding" EXACT [] xref: GO:0016151 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0003043 name: mercury (II) reductase activity namespace: molecular_function def: "Catalysis of the reaction: Hg + NADP+ + H+ = Hg2+ + NADPH + H+." [EC:1.16.1.1] subset: gosubset_prok synonym: "Hg:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.1] synonym: "mer A" RELATED [EC:1.16.1.1] synonym: "mercurate(II) reductase activity" EXACT [EC:1.16.1.1] synonym: "mercuric ion reductase activity" EXACT [EC:1.16.1.1] synonym: "mercuric reductase activity" EXACT [EC:1.16.1.1] synonym: "mercury reductase activity" EXACT [EC:1.16.1.1] synonym: "mercury(II) reductase activity" EXACT [EC:1.16.1.1] synonym: "reduced NADP:mercuric ion oxidoreductase activity" EXACT [EC:1.16.1.1] xref: EC:1.16.1.1 xref: GO:0016152 xref: GO:0018692 xref: MetaCyc:MERCURY-(II)-REDUCTASE-RXN xref: UM-BBD_enzymeID:e0056 is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0003044 name: urocanate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 4,5-dihydro-4-oxo-5-imidazolepropanoate = urocanate + H2O." [EC:4.2.1.49] subset: gosubset_prok synonym: "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)" EXACT [EC:4.2.1.49] synonym: "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity" EXACT [EC:4.2.1.49] synonym: "imidazolonepropionate hydrolase activity" EXACT [EC:4.2.1.49] synonym: "urocanase activity" EXACT [EC:4.2.1.49] xref: EC:4.2.1.49 xref: GO:0016153 xref: MetaCyc:UROCANATE-HYDRATASE-RXN xref: Reactome:23891 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003045 name: pyrimidine-nucleoside phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate." [EC:2.4.2.2] subset: gosubset_prok synonym: "Py-NPase activity" EXACT [EC:2.4.2.2] synonym: "pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.2] xref: EC:2.4.2.2 xref: GO:0016154 xref: MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0003046 name: formyltetrahydrofolate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+." [EC:1.5.1.6] synonym: "10-formyl tetrahydrofolate:NADP oxidoreductase activity" EXACT [EC:1.5.1.6] synonym: "10-formyl-H2PtGlu:NADP oxidoreductase activity" EXACT [EC:1.5.1.6] synonym: "10-formyl-H4folate dehydrogenase activity" EXACT [EC:1.5.1.6] synonym: "10-formyltetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.6] synonym: "10-formyltetrahydrofolate:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.6] synonym: "N10-formyltetrahydrofolate dehydrogenase activity" EXACT [EC:1.5.1.6] xref: EC:1.5.1.6 xref: GO:0016155 xref: MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003047 name: fumarate reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: succinate + NAD+ = fumarate + NADH + H+." [EC:1.3.1.6] subset: gosubset_prok synonym: "NADH-dependent fumarate reductase activity" EXACT [EC:1.3.1.6] synonym: "NADH-fumarate reductase activity" EXACT [EC:1.3.1.6] synonym: "succinate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.6] xref: EC:1.3.1.6 xref: GO:0016156 xref: MetaCyc:FUMARATE-REDUCTASE-(NADH)-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003048 name: sucrose synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose." [EC:2.4.1.13] subset: gosubset_prok synonym: "NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.13] synonym: "sucrose synthetase activity" EXACT [EC:2.4.1.13] synonym: "sucrose-UDP glucosyltransferase activity" EXACT [EC:2.4.1.13] synonym: "sucrose-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.13] synonym: "UDP-glucose-fructose glucosyltransferase activity" EXACT [EC:2.4.1.13] synonym: "UDPglucose-fructose glucosyltransferase activity" EXACT [EC:2.4.1.13] synonym: "uridine diphosphoglucose-fructose glucosyltransferase activity" EXACT [EC:2.4.1.13] xref: EC:2.4.1.13 xref: GO:0016157 xref: MetaCyc:SUCROSE-SYNTHASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0003049 name: 3-phytase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate." [EC:3.1.3.8] subset: gosubset_prok synonym: "1-phytase activity" EXACT [EC:3.1.3.8] synonym: "myo-inositol-hexakisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.8] synonym: "myo-inositol-hexaphosphate 3-phosphohydrolase activity" EXACT [] synonym: "phytase activity" BROAD [] synonym: "phytate 1-phosphatase activity" EXACT [EC:3.1.3.8] synonym: "phytate 3-phosphatase activity" EXACT [] xref: EC:3.1.3.8 xref: GO:0016158 xref: MetaCyc:RXN0-1001 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0003050 name: muconolactone delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate." [EC:5.3.3.4] subset: gosubset_prok synonym: "5-oxo-4,5-dihydrofuran-2-acetate delta3-delta2-isomerase activity" EXACT [EC:5.3.3.4] synonym: "muconolactone D-isomerase activity" EXACT [] synonym: "muconolactone isomerase activity" EXACT [EC:5.3.3.4] xref: EC:5.3.3.4 xref: GO:0016159 xref: MetaCyc:MUCONOLACTONE-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0003051 name: amylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of amylose or an amylose derivative." [GOC:ai] subset: gosubset_prok xref: EC:3.2.1.- xref: GO:0016160 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003052 name: beta-amylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains." [EC:3.2.1.2] subset: gosubset_prok synonym: "1,4-alpha-D-glucan maltohydrolase activity" EXACT [EC:3.2.1.2] synonym: "beta amylase activity" EXACT [EC:3.2.1.2] synonym: "glycogenase activity" BROAD [EC:3.2.1.2] synonym: "saccharogen amylase activity" EXACT [EC:3.2.1.2] xref: EC:3.2.1.2 xref: GO:0016161 xref: MetaCyc:3.2.1.2-RXN is_a: CCO:F0003051 ! amylase activity [Term] id: CCO:F0003053 name: cellulose 1,4-beta-cellobiosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains." [EC:3.2.1.91] subset: gosubset_prok synonym: "1,4-beta-cellobiohydrolase activity" EXACT [EC:3.2.1.91] synonym: "1,4-beta-D-glucan cellobiohydrolase activity" EXACT [EC:3.2.1.91] synonym: "1,4-beta-glucan cellobiosidase activity" EXACT [EC:3.2.1.91] synonym: "avicelase activity" BROAD [EC:3.2.1.91] synonym: "beta-1,4-glucan cellobiohydrolase activity" EXACT [EC:3.2.1.91] synonym: "beta-1,4-glucan cellobiosylhydrolase activity" EXACT [EC:3.2.1.91] synonym: "C1 cellulase activity" EXACT [EC:3.2.1.91] synonym: "CBH 1" RELATED [EC:3.2.1.91] synonym: "cellobiohydrolase activity" EXACT [EC:3.2.1.91] synonym: "cellobiohydrolase I" RELATED [EC:3.2.1.91] synonym: "cellobiosidase activity" EXACT [EC:3.2.1.91] synonym: "exo-1,4-beta-D-glucanase activity" EXACT [EC:3.2.1.91] synonym: "exo-beta-1,4-glucan cellobiohydrolase activity" EXACT [EC:3.2.1.91] synonym: "exo-cellobiohydrolase activity" EXACT [EC:3.2.1.91] synonym: "exocellobiohydrolase activity" EXACT [EC:3.2.1.91] synonym: "exoglucanase activity" EXACT [EC:3.2.1.91] xref: EC:3.2.1.91 xref: GO:0016162 xref: MetaCyc:3.2.1.91-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003054 name: nitrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate." [EC:1.18.6.1] subset: gosubset_prok synonym: "iron-iron nitrogenase activity" NARROW [] synonym: "molybdenum-iron nitrogenase activity" NARROW [] synonym: "reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity" EXACT [EC:1.18.6.1] synonym: "vanadium-iron nitrogenase activity" NARROW [] xref: EC:1.18.6.1 xref: GO:0016163 xref: MetaCyc:NITROGENASE-RXN xref: UM-BBD_enzymeID:e0395 is_a: CCO:F0003313 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor [Term] id: CCO:F0003055 name: Mo-molybdopterin oxidoreductase activity namespace: molecular_function subset: gosubset_prok synonym: "molybdopterin oxidoreductase activity" EXACT [] xref: GO:0016164 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003056 name: lipoxygenase activity namespace: molecular_function def: "Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate." [EC:1.13.11.12] subset: gosubset_prok synonym: "carotene oxidase activity" NARROW [EC:1.13.11.12] synonym: "fat oxidase activity" EXACT [EC:1.13.11.12] synonym: "linoleate:oxygen 13-oxidoreductase activity" EXACT [EC:1.13.11.12] synonym: "lionoleate:O2 oxidoreductase activity" EXACT [EC:1.13.11.12] synonym: "lipoperoxidase activity" EXACT [EC:1.13.11.12] synonym: "lipoxidase activity" EXACT [EC:1.13.11.12] synonym: "lipoxydase activity" EXACT [EC:1.13.11.12] xref: EC:1.13.11.12 xref: GO:0016165 xref: MetaCyc:LIPOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003057 name: phytoene dehydrogenase activity namespace: molecular_function def: "Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene." [http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/terp/carot.html] subset: gosubset_prok xref: EC:1.3.-.- xref: GO:0016166 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003058 name: glial cell line-derived neurotrophic factor receptor activity namespace: molecular_function xref: GO:0016167 is_a: CCO:F0001244 ! hematopoietin/interferon-class (D200-domain) cytokine receptor activity [Term] id: CCO:F0003059 name: chlorophyll binding namespace: molecular_function def: "Interacting selectively with chlorophyll; any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment." [GOC:jl] subset: gosubset_prok xref: GO:0016168 is_a: CCO:F0006264 ! tetrapyrrole binding [Term] id: CCO:F0003060 name: bacteriochlorophyll c binding namespace: molecular_function def: "Interacting selectively with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria." [ISBN:0192800981] subset: gosubset_prok xref: GO:0016169 is_a: CCO:F0005658 ! bacteriochlorophyll binding [Term] id: CCO:F0003061 name: interleukin-15 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-15 receptor." [GOC:ai] synonym: "IL-15" NARROW [] synonym: "interleukin-15 receptor ligand" NARROW [] xref: GO:0016170 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0003062 name: NAD(P)H oxidase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + H2O2." [EC:1.6.3.1] synonym: "dual oxidase activity" RELATED [EC:1.6.3.1] synonym: "NAD(P)H:oxygen oxidoreductase activity" EXACT [EC:1.6.3.1] synonym: "NADPH oxidase" BROAD [EC:1.6.3.1] synonym: "p138tox" RELATED [EC:1.6.3.1] synonym: "ThOX activity" NARROW [EC:1.6.3.1] synonym: "THOX2 activity" NARROW [EC:1.6.3.1] synonym: "thyroid NADPH oxidase activity" NARROW [] synonym: "thyroid oxidase 2 activity" NARROW [EC:1.6.3.1] synonym: "thyroid oxidase activity" NARROW [EC:1.6.3.1] xref: EC:1.6.3.1 xref: GO:0016174 is_a: CCO:F0007989 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor [Term] id: CCO:F0003063 name: superoxide-generating NADPH oxidase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-." [GOC:ai, PMID:10806195] synonym: "cytochrome B-245" RELATED [] xref: EC:1.6.3.- xref: GO:0016175 is_a: CCO:F0007989 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor [Term] id: CCO:F0003064 name: superoxide-generating NADPH oxidase activator activity namespace: molecular_function def: "Increases the activity of the enzyme superoxide-generating NADPH oxidase." [GOC:ai] synonym: "neutrophil cytosol factor 2" NARROW [] xref: GO:0016176 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0003065 name: selenocysteine methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine." [EC:2.1.1.-, PMID:10026151] xref: EC:2.1.1.- xref: GO:0016205 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0003066 name: catechol O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol." [EC:2.1.1.6] subset: gosubset_prok synonym: "catechol methyltransferase activity" EXACT [EC:2.1.1.6] synonym: "catecholamine O-methyltransferase activity" EXACT [EC:2.1.1.6] synonym: "COMT I" RELATED [EC:2.1.1.6] synonym: "COMT II" RELATED [EC:2.1.1.6] synonym: "MB-COMT (membrane-bound form of catechol-O-methyltransferase)" RELATED [EC:2.1.1.6] synonym: "S-adenosyl-L-methionine:catechol O-methyltransferase activity" EXACT [EC:2.1.1.6] synonym: "S-COMT (soluble form of catechol-O-methyltransferase)" RELATED [EC:2.1.1.6] xref: EC:2.1.1.6 xref: GO:0016206 xref: MetaCyc:CATECHOL-O-METHYLTRANSFERASE-RXN xref: Reactome:24294 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003067 name: 4-coumarate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA." [EC:6.2.1.12] subset: gosubset_prok synonym: "4-coumarate-CoA synthetase activity" EXACT [] synonym: "4-coumarate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.12] synonym: "4-coumarate:CoA ligase activity" EXACT [] synonym: "4-coumarate:coenzyme A ligase activity" EXACT [EC:6.2.1.12] synonym: "4-coumaroyl-CoA synthase activity" EXACT [EC:6.2.1.12] synonym: "4-coumaroyl-CoA synthetase activity" EXACT [EC:6.2.1.12] synonym: "4-coumaryl-CoA synthetase activity" EXACT [EC:6.2.1.12] synonym: "4CL" RELATED [EC:6.2.1.12] synonym: "caffeolyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] synonym: "feruloyl CoA ligase activity" EXACT [EC:6.2.1.12] synonym: "feruloyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] synonym: "hydroxycinnamate:CoA ligase activity" EXACT [EC:6.2.1.12] synonym: "hydroxycinnamoyl CoA synthetase activity" EXACT [EC:6.2.1.12] synonym: "p-coumaroyl CoA ligase activity" EXACT [EC:6.2.1.12] synonym: "p-coumaryl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] synonym: "p-coumaryl-CoA ligase activity" EXACT [EC:6.2.1.12] synonym: "p-coumaryl-CoA synthetase activity" EXACT [EC:6.2.1.12] synonym: "p-hydroxycinnamic acid:CoA ligase activity" EXACT [EC:6.2.1.12] synonym: "p-hydroxycinnamoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] synonym: "sinapoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.12] xref: EC:6.2.1.12 xref: GO:0016207 xref: MetaCyc:4-COUMARATE--COA-LIGASE-RXN is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0003068 name: AMP binding namespace: molecular_function def: "Interacting selectively with AMP, adenosine monophosphate." [GOC:go_curators] subset: gosubset_prok xref: GO:0016208 is_a: CCO:F0005022 ! adenyl ribonucleotide binding [Term] id: CCO:F0003069 name: antioxidant activity namespace: molecular_function def: "Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: gosubset_prok xref: GO:0016209 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0003070 name: naringenin-chalcone synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2." [EC:2.3.1.74] subset: gosubset_prok synonym: "chalcone synthase activity" EXACT [EC:2.3.1.74] synonym: "chalcone synthetase activity" EXACT [] synonym: "CHS" EXACT [] synonym: "DOCS" NARROW [] synonym: "flavanone synthase activity" EXACT [EC:2.3.1.74] synonym: "flavonone synthase activity" EXACT [EC:2.3.1.74] synonym: "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)" BROAD [EC:2.3.1.74] xref: EC:2.3.1.74 xref: GO:0016210 xref: MetaCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0003071 name: ammonia ligase activity namespace: molecular_function def: "Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok xref: EC:6.3.1.- xref: GO:0016211 is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0003072 name: kynurenine-oxoglutarate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate." [EC:2.6.1.7] subset: gosubset_prok synonym: "kynurenine 2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.7] synonym: "kynurenine aminotransferase activity" EXACT [EC:2.6.1.7] synonym: "kynurenine transaminase (cyclizing)" EXACT [EC:2.6.1.7] synonym: "kynurenine--oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.7] synonym: "kynurenine-oxoglutarate aminotransferase activity" EXACT [] synonym: "L-kynurenine aminotransferase activity" EXACT [EC:2.6.1.7] synonym: "L-kynurenine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.7] xref: EC:2.6.1.7 xref: GO:0016212 xref: MetaCyc:2.6.1.7-RXN xref: Reactome:24302 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0003073 name: linoleoyl-CoA desaturase activity namespace: molecular_function def: "Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O." [EC:1.14.19.3] comment: Note that this function was formerly EC:1.14.99.25. subset: gosubset_prok synonym: "delta(6)-acyl CoA desaturase activity" BROAD [] synonym: "delta(6)-desaturase activity" BROAD [] synonym: "delta(6)-fatty acyl-CoA desaturase activity" BROAD [] synonym: "delta6-acyl CoA desaturase activity" EXACT [EC:1.14.19.3] synonym: "delta6-desaturase activity" EXACT [EC:1.14.19.3] synonym: "delta6-fatty acyl-CoA desaturase activity" EXACT [EC:1.14.19.3] synonym: "fatty acid 6-desaturase activity" BROAD [] synonym: "fatty acid delta(6)-desaturase activity" BROAD [] synonym: "fatty acid delta6-desaturase activity" EXACT [EC:1.14.19.3] synonym: "linoleate desaturase activity" RELATED [] synonym: "linoleic acid desaturase activity" RELATED [] synonym: "linoleic desaturase activity" RELATED [] synonym: "linoleoyl CoA desaturase activity" EXACT [] synonym: "linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.19.3] synonym: "linoleoyl-coenzyme A desaturase activity" EXACT [] synonym: "long-chain fatty acid delta(6)-desaturase activity" BROAD [] synonym: "long-chain fatty acid delta6-desaturase activity" EXACT [EC:1.14.19.3] xref: EC:1.14.19.3 xref: GO:0016213 xref: MetaCyc:1.14.19.3-RXN is_a: CCO:F0003300 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Term] id: CCO:F0003074 name: CoA desaturase activity namespace: molecular_function subset: gosubset_prok xref: EC:1.14.99.- xref: GO:0016215 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003075 name: isopenicillin-N synthase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine = isopenicillin-N + H2O." [EC:1.21.3.1, PMID:12926272] subset: gosubset_prok synonym: "isopenicillin N synthase activity" EXACT [EC:1.21.3.1] synonym: "isopenicillin-N synthetase activity" EXACT [] synonym: "N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine:oxygen oxidoreductase (cyclizing)" EXACT [EC:1.21.3.1] xref: EC:1.21.3.1 xref: GO:0016216 xref: MetaCyc:1.21.3.1-RXN is_a: CCO:F0006307 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor [Term] id: CCO:F0003076 name: N-ethylammeline chlorohydrolase activity namespace: molecular_function xref: GO:0016217 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003077 name: polyketide synthase activity namespace: molecular_function subset: gosubset_prok xref: GO:0016218 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003078 name: GDP-dissociation stimulator activity namespace: molecular_function synonym: "GDS" EXACT [] xref: GO:0016219 is_a: CCO:F0001388 ! small GTPase regulator activity [Term] id: CCO:F0003079 name: RAL GDP-dissociation stimulator activity namespace: molecular_function xref: GO:0016220 is_a: CCO:F0003078 ! GDP-dissociation stimulator activity [Term] id: CCO:F0003080 name: beta-alanine-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine." [EC:2.6.1.18] subset: gosubset_prok synonym: "beta-alanine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.18] synonym: "beta-alanine-alpha-alanine transaminase activity" EXACT [EC:2.6.1.18] synonym: "beta-alanine-pyruvate aminotransferase activity" EXACT [] synonym: "L-alanine:3-oxopropanoate aminotransferase activity" EXACT [EC:2.6.1.18] synonym: "omega-amino acid--pyruvate aminotransferase activity" EXACT [EC:2.6.1.18] xref: EC:2.6.1.18 xref: GO:0016223 xref: MetaCyc:2.6.1.18-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0003081 name: tRNA sulfurtransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide." [EC:2.8.1.4] synonym: "L-cysteine:tRNA sulfurtransferase activity" EXACT [EC:2.8.1.4] synonym: "ribonucleate sulfurtransferase activity" EXACT [EC:2.8.1.4] synonym: "RNA sulfurtransferase activity" EXACT [EC:2.8.1.4] synonym: "transfer ribonucleate sulfurtransferase activity" EXACT [EC:2.8.1.4] synonym: "transfer RNA sulfurtransferase activity" EXACT [EC:2.8.1.4] synonym: "transfer RNA thiolase activity" EXACT [EC:2.8.1.4] synonym: "tRNA sulphurtransferase activity" EXACT [] xref: EC:2.8.1.4 xref: GO:0016227 xref: MetaCyc:TRNA-SULFURTRANSFERASE-RXN is_a: CCO:F0003355 ! sulfurtransferase activity [Term] id: CCO:F0003082 name: steroid dehydrogenase activity namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative." [GOC:mah] subset: gosubset_prok xref: EC:1.1.1.- xref: GO:0016229 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003083 name: sphingomyelin phosphodiesterase activator activity namespace: molecular_function def: "Increases the activity of the enzyme sphingomyelin phosphodiesterase." [GOC:ai] synonym: "neutral sphingomyelinase activator" EXACT [] xref: GO:0016230 is_a: CCO:F0003028 ! phospholipase activator activity [Term] id: CCO:F0003084 name: beta-N-acetylglucosaminidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides." [EC:3.2.1.52, MetaCyc:3.2.1.52-RXN] xref: GO:0016231 is_a: CCO:F0000947 ! beta-N-acetylhexosaminidase activity [Term] id: CCO:F0003085 name: HNK-1 sulfotransferase activity namespace: molecular_function def: "Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1,3)-Gal-beta-(1,4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1,3)-Gal-beta-(1,4)-GlcNAc-beta-(1->R)." [PMID:9478973] synonym: "HNK-1 sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0016232 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0003086 name: channel regulator activity namespace: molecular_function subset: gosubset_prok xref: GO:0016247 is_a: CCO:F0002865 ! auxiliary transport protein activity [Term] id: CCO:F0003087 name: channel inhibitor activity namespace: molecular_function subset: gosubset_prok xref: GO:0016248 is_a: CCO:F0003086 ! channel regulator activity [Term] id: CCO:F0003088 name: channel localizer activity namespace: molecular_function def: "Functions to locate the position of ion channels in the cell." [PMID:10218120] xref: GO:0016249 is_a: CCO:F0002865 ! auxiliary transport protein activity [Term] id: CCO:F0003089 name: N-sulfoglucosamine sulfohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + SO4(2-) (sulfate)." [EC:3.10.1.1] synonym: "2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)" EXACT [EC:3.10.1.1] synonym: "heparin sulfamidase activity" EXACT [EC:3.10.1.1] synonym: "N-sulfo-D-glucosamine sulfohydrolase activity" EXACT [EC:3.10.1.1] synonym: "N-sulphoglucosamine sulphohydrolase activity" EXACT [] synonym: "sulfoglucosamine sulfamidase activity" EXACT [EC:3.10.1.1] synonym: "sulphamidase activity" EXACT [EC:3.10.1.1] xref: EC:3.10.1.1 xref: GO:0016250 xref: MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN is_a: CCO:F0003393 ! hydrolase activity, acting on acid sulfur-nitrogen bonds [Term] id: CCO:F0003090 name: general RNA polymerase II transcription factor activity namespace: molecular_function def: "Any function that supports basal (unregulated) transcription of genes by core RNA polymerase II. Five general transcription factors are necessary and sufficient for such basal transcription in yeast: TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBF)." [PMID:10384286, PMID:9774831] xref: GO:0003703 xref: GO:0016251 is_a: CCO:F0000291 ! RNA polymerase II transcription factor activity [Term] id: CCO:F0003091 name: nonspecific RNA polymerase II transcription factor activity namespace: molecular_function def: "Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set." [GOC:jl] xref: GO:0016252 is_a: CCO:F0000291 ! RNA polymerase II transcription factor activity [Term] id: CCO:F0003092 name: UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + peptide = UDP + N-acetyl-beta-D-glucosaminyl-peptide." [UniProtKB:O15294] xref: EC:2.4.1.- xref: GO:0016253 is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0003093 name: protein N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein." [EC:2.4.1.94] synonym: "N-GlcNAc transferase activity" EXACT [EC:2.4.1.94] synonym: "O-GlcNAc transferase activity" EXACT [] synonym: "UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase activity" EXACT [] synonym: "uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase activity" EXACT [] synonym: "uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase activity" EXACT [] xref: EC:2.4.1.94 xref: GO:0016262 xref: MetaCyc:2.4.1.94-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0003094 name: glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan." [EC:2.4.1.122, GOC:ma] synonym: "Core 1 GalT" RELATED [] synonym: "UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.122] synonym: "UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.122] synonym: "uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity" EXACT [EC:2.4.1.122] xref: EC:2.4.1.122 xref: GO:0016263 xref: MetaCyc:2.4.1.122-RXN is_a: CCO:F0007345 ! beta-1,3-galactosyltransferase activity [Term] id: CCO:F0003095 name: arginine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue." [GOC:mah] xref: EC:2.1.1.- xref: GO:0016273 is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003096 name: protein-arginine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue in a protein substrate." [GOC:mah, PMID:12351636] xref: EC:2.1.1.- xref: GO:0016274 is_a: CCO:F0003095 ! arginine N-methyltransferase activity [Term] id: CCO:F0003099 name: lysine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0016278 is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003100 name: protein-lysine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate." [PMID:12054878] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0016279 is_a: CCO:F0001813 ! protein methyltransferase activity is_a: CCO:F0003099 ! lysine N-methyltransferase activity [Term] id: CCO:F0003101 name: alanine aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide." [GOC:jl] subset: gosubset_prok xref: EC:3.4.11.- xref: GO:0016284 is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0003102 name: cytosol alanyl aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides." [EC:3.4.11.14] subset: gosubset_prok synonym: "aminopolypeptidase activity" EXACT [EC:3.4.11.14] synonym: "arylamidase activity" NARROW [EC:3.4.11.14] synonym: "cytosol aminopeptidase III activity" NARROW [EC:3.4.11.14] synonym: "human liver aminopeptidase" NARROW [EC:3.4.11.14] synonym: "liver aminopeptidase activity" NARROW [EC:3.4.11.14] synonym: "puromycin-sensitive aminopeptidase activity" NARROW [EC:3.4.11.14] synonym: "soluble alanyl aminopeptidase activity" EXACT [EC:3.4.11.14] synonym: "thiol-activated aminopeptidase activity" EXACT [EC:3.4.11.14] xref: EC:3.4.11.14 xref: GO:0016285 xref: MetaCyc:3.4.11.14-RXN is_a: CCO:F0001785 ! metalloexopeptidase activity is_a: CCO:F0003101 ! alanine aminopeptidase activity [Term] id: CCO:F0003103 name: small conductance calcium-activated potassium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, OMIM:602754] synonym: "SK calcium-activated potassium channel activity " EXACT [] synonym: "SK KCa channels" EXACT [] synonym: "small conductance KCa channels " EXACT [] xref: GO:0016286 is_a: CCO:F0002726 ! calcium-activated potassium channel activity [Term] id: CCO:F0003104 name: glycerone-phosphate O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate." [EC:2.3.1.42] synonym: "acyl-CoA:glycerone-phosphate O-acyltransferase activity" EXACT [EC:2.3.1.42] synonym: "dihydroxyacetone phosphate acyltransferase activity" EXACT [EC:2.3.1.42] xref: EC:2.3.1.42 xref: GO:0016287 xref: MetaCyc:2.3.1.42-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0003105 name: CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group." [GOC:ai] subset: gosubset_prok xref: EC:3.1.2.- xref: GO:0016289 is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0003106 name: palmitoyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate." [EC:3.1.2.2] subset: gosubset_prok synonym: "fatty acyl thioesterase I" RELATED [EC:3.1.2.2] synonym: "long-chain fatty-acyl-CoA hydrolase activity" EXACT [] synonym: "palmitoyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.2] synonym: "palmitoyl thioesterase activity" EXACT [EC:3.1.2.2] synonym: "palmitoyl-CoA deacylase activity" EXACT [EC:3.1.2.2] synonym: "palmityl thioesterase activity" EXACT [EC:3.1.2.2] synonym: "palmityl thioesterase I" RELATED [EC:3.1.2.2] synonym: "palmityl-CoA deacylase activity" EXACT [EC:3.1.2.2] xref: EC:3.1.2.2 xref: GO:0016290 xref: GO:0016293 xref: MetaCyc:PALMITOYL-COA-HYDROLASE-RXN xref: MetaCyc:PWY-5148 is_a: CCO:F0003107 ! acyl-CoA thioesterase activity [Term] id: CCO:F0003107 name: acyl-CoA thioesterase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + H2O = corresponding fatty acid + CoA." [PMID:14660652] subset: gosubset_prok synonym: "acyl-CoA thioesterase I activity" NARROW [] synonym: "acyl-CoA thioesterase II activity" NARROW [] synonym: "acyl-CoA thiolesterase activity" EXACT [] xref: EC:3.1.2.- xref: GO:0008778 xref: GO:0016291 xref: GO:0016292 is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0003108 name: myristoyl-[acyl-carrier-protein] hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate." [EC:3.1.2.14] synonym: "myristoyl-[acyl-carrier protein] hydrolase activity" EXACT [] synonym: "myristoyl-ACP hydrolase activity" EXACT [] synonym: "tetradecanoyl-[acyl-carrier-protein] hydrolase activity" EXACT [] synonym: "tetradecanoyl-ACP hydrolase activity" EXACT [] xref: GO:0016295 is_a: CCO:F0003110 ! acyl-[acyl-carrier-protein] hydrolase activity [Term] id: CCO:F0003109 name: palmitoyl-[acyl-carrier-protein] hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate." [EC:3.1.2.14] synonym: "palmitoyl-[acyl-carrier protein] hydrolase activity" EXACT [] synonym: "palmitoyl-ACP hydrolase activity" EXACT [] xref: GO:0016296 is_a: CCO:F0003110 ! acyl-[acyl-carrier-protein] hydrolase activity [Term] id: CCO:F0003110 name: acyl-[acyl-carrier-protein] hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + organic acid." [EC:3.1.2.14] subset: gosubset_prok synonym: "acyl-[acyl-carrier protein] hydrolase activity" EXACT [] synonym: "acyl-ACP hydrolase activity" EXACT [] synonym: "acyl-ACP thioesterase activity" EXACT [] synonym: "acyl-ACP-hydrolase activity" EXACT [EC:3.1.2.14] synonym: "acyl-acyl carrier protein hydrolase activity" EXACT [EC:3.1.2.14] synonym: "acyl-acyl-carrier-protein hydrolase activity" EXACT [EC:3.1.2.14] synonym: "S-acyl fatty acid synthase thioesterase activity" EXACT [EC:3.1.2.14] xref: GO:0010281 xref: GO:0016297 is_a: CCO:F0000733 ! fatty-acid synthase activity is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0003111 name: lipase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a lipid or phospholipid." [GOC:mah] subset: gosubset_prok xref: EC:3.1.1.- xref: GO:0016298 xref: Reactome:1913 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0003112 name: regulator of G-protein signaling activity namespace: molecular_function def: "Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form." [UniProtKB:O08774] synonym: "regulator of G protein signaling activity" EXACT [] synonym: "regulator of G protein signalling activity" EXACT [] synonym: "regulator of G-protein signalling activity" EXACT [] synonym: "RGS" EXACT [] xref: GO:0016299 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0003113 name: tRNA (uracil) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule." [GOC:mah] comment: Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698). subset: gosubset_prok synonym: "tRNA (uridine) methyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0016300 xref: GO:0016431 is_a: CCO:F0001762 ! tRNA methyltransferase activity [Term] id: CCO:F0003114 name: kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. subset: goslim_generic subset: goslim_goa subset: goslim_plant subset: gosubset_prok synonym: "phosphokinase activity" EXACT [] xref: GO:0016301 xref: Reactome:1423 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003115 name: 1-phosphatidylinositol-3-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate." [EC:2.7.1.137, PMID:9759495] synonym: "1-phosphatidylinositol 3-kinase activity" EXACT [] synonym: "ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase activity" EXACT [EC:2.7.1.137] synonym: "phosphatidylinositol 3-kinase activity" EXACT [] synonym: "phosphatidylinositol 3-kinase activity, class I" NARROW [] synonym: "phosphatidylinositol 3-kinase activity, class II" NARROW [] synonym: "phosphatidylinositol 3-kinase activity, class III" NARROW [] synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" NARROW [] synonym: "PI3-kinase activity" EXACT [EC:2.7.1.137] synonym: "PI3K" EXACT [] synonym: "PtdIns-3-kinase activity" EXACT [EC:2.7.1.137] synonym: "type I phosphatidylinositol kinase activity" NARROW [EC:2.7.1.137] synonym: "type III phosphoinositide 3-kinase activity" NARROW [EC:2.7.1.137] synonym: "Vps34p" RELATED [EC:2.7.1.137] xref: EC:2.7.1.137 xref: GO:0004429 xref: GO:0016303 xref: MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN is_a: CCO:F0005553 ! phosphoinositide 3-kinase activity [Term] id: CCO:F0003116 name: phosphatidylinositol phosphate kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of phosphatidylinositol phosphate to produce phosphatidylinositol bisphosphate." [EC:2.7.1.-, PMID:9759495] subset: gosubset_prok xref: EC:2.7.1.- xref: GO:0016307 is_a: CCO:F0000204 ! lipid kinase activity is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0003117 name: 1-phosphatidylinositol-4-phosphate 5-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [EC:2.7.1.68] subset: gosubset_prok synonym: "1-phosphatidylinositol-4-phosphate kinase activity" BROAD [] synonym: "1-phosphatidylinositol-4-phosphate kinase, class IA" NARROW [] synonym: "1-phosphatidylinositol-4-phosphate kinase, class IB" NARROW [] synonym: "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.68] synonym: "diphosphoinositide kinase activity" BROAD [EC:2.7.1.68] synonym: "phosphatidylinositol 4-phosphate kinase activity" BROAD [EC:2.7.1.68] synonym: "phosphatidylinositol-4-phosphate 5-kinase activity" EXACT [EC:2.7.1.68] synonym: "PIP kinase activity" BROAD [EC:2.7.1.68] synonym: "PIP5K" EXACT [] synonym: "PtdIns(4)P-5-kinase activity" EXACT [EC:2.7.1.68] synonym: "type I PIP kinase activity" NARROW [EC:2.7.1.68] xref: EC:2.7.1.68 xref: GO:0004431 xref: GO:0016308 xref: GO:0045215 xref: MetaCyc:2.7.1.68-RXN is_a: CCO:F0003116 ! phosphatidylinositol phosphate kinase activity [Term] id: CCO:F0003118 name: 1-phosphatidylinositol-5-phosphate 4-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate." [EC:2.7.1.149] synonym: "1-phosphatidylinositol-5-phosphate kinase" BROAD [] synonym: "ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity" EXACT [EC:2.7.1.149] synonym: "PIP4K" EXACT [] synonym: "type II PIP kinase activity" NARROW [EC:2.7.1.149] xref: EC:2.7.1.149 xref: GO:0016309 xref: MetaCyc:2.7.1.149-RXN is_a: CCO:F0003116 ! phosphatidylinositol phosphate kinase activity [Term] id: CCO:F0003119 name: inositol bisphosphate phosphatase activity namespace: molecular_function def: "Catalysis of the removal of one of the two phosphate groups of an inositol bisphosphate." [GOC:hb] xref: EC:3.1.3.- xref: GO:0016312 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0003120 name: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidyl inositol-4,5-bisphosphate + phosphate." [EC:3.1.3.67] synonym: "1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.67] synonym: "MMAC1" RELATED [EC:3.1.3.67] synonym: "phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity" EXACT [EC:3.1.3.67] xref: EC:3.1.3.67 xref: GO:0016314 xref: MetaCyc:3.1.3.67-RXN xref: Reactome:24758 is_a: CCO:F0005684 ! lipid phosphatase activity is_a: CCO:F0008467 ! phosphatidylinositol trisphosphate phosphatase activity [Term] id: CCO:F0003121 name: phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate." [EC:3.1.3.66, GOC:hb] synonym: "1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity" EXACT [EC:3.1.3.66] synonym: "D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity" EXACT [EC:3.1.3.66] synonym: "inositol polyphosphate 4-phosphatase type II activity" RELATED [EC:3.1.3.66] synonym: "inositol-1,4,-bisphosphate 4-phosphatase activity" EXACT [] synonym: "inositol-3,4-bisphosphate 4-phosphatase activity" EXACT [] xref: EC:3.1.3.66 xref: GO:0004440 xref: GO:0016316 xref: MetaCyc:3.1.3.66-RXN is_a: CCO:F0005684 ! lipid phosphatase activity is_a: CCO:F0008466 ! phosphatidylinositol bisphosphate phosphatase activity is_a: CCO:F0008468 ! phosphoinositide 4-phosphatase activity [Term] id: CCO:F0003122 name: activin receptor activity, type I namespace: molecular_function def: "Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals." [GOC:mah, PMID:8622651] synonym: "type I activin receptor activity" EXACT [] xref: GO:0016361 is_a: CCO:F0001355 ! transforming growth factor beta receptor activity, type I is_a: CCO:F0003510 ! activin receptor activity [Term] id: CCO:F0003123 name: activin receptor activity, type II namespace: molecular_function def: "Combining with activin to initiate a change in cell activity; upon ligand binding, binds to catalyzes the phosphorylation of type I activin receptor." [GOC:mah, PMID:8622651] synonym: "type II activin receptor activity" EXACT [] xref: GO:0016362 is_a: CCO:F0001356 ! transforming growth factor beta receptor activity, type II is_a: CCO:F0003510 ! activin receptor activity [Term] id: CCO:F0003124 name: palmitoyl-CoA oxidase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + H2O2." [GOC:jsg] xref: EC:1.3.3.- xref: GO:0016401 is_a: CCO:F0000482 ! acyl-CoA oxidase activity [Term] id: CCO:F0003125 name: pristanoyl-CoA oxidase activity namespace: molecular_function def: "Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + H2O2." [GOC:jsg] xref: EC:1.3.3.- xref: GO:0016402 is_a: CCO:F0000482 ! acyl-CoA oxidase activity [Term] id: CCO:F0003126 name: dimethylargininase activity namespace: molecular_function def: "Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline." [EC:3.5.3.18] subset: gosubset_prok synonym: "dimethylarginine dimethylaminohydrolase activity" EXACT [EC:3.5.3.18] synonym: "N(G),N(G)-dimethylarginine dimethylaminohydrolase activity" EXACT [EC:3.5.3.18] synonym: "NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity" EXACT [EC:3.5.3.18] synonym: "NG,NG-dimethylarginine dimethylaminohydrolase activity" EXACT [EC:3.5.3.18] xref: EC:3.5.3.18 xref: GO:0016403 xref: MetaCyc:DIMETHYLARGININASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003127 name: 15-hydroxyprostaglandin dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+." [EC:1.1.1.141] synonym: "(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity" EXACT [EC:1.1.1.141] synonym: "11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity" EXACT [EC:1.1.1.141] synonym: "15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.141] synonym: "15-hydroxyprostanoic dehydrogenase activity" EXACT [EC:1.1.1.141] synonym: "15-OH-PGDH" RELATED [EC:1.1.1.141] synonym: "NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)" EXACT [EC:1.1.1.141] synonym: "NAD-specific 15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.141] synonym: "prostaglandin dehydrogenase activity" EXACT [EC:1.1.1.141] xref: EC:1.1.1.141 xref: GO:0016404 xref: MetaCyc:1.1.1.141-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003128 name: CoA-ligase activity namespace: molecular_function def: "Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA." [GOC:ai] subset: gosubset_prok xref: GO:0016405 xref: Reactome:10971 is_a: CCO:F0003436 ! ligase activity, forming carbon-sulfur bonds [Term] id: CCO:F0003129 name: carnitine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016406 is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0003130 name: acetyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acetyl group to an acceptor molecule." [GOC:ai] subset: gosubset_prok synonym: "acetylase activity" EXACT [] xref: EC:2.3.1.- xref: GO:0016407 xref: Reactome:1621 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003131 name: C-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016408 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003132 name: palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016409 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003133 name: N-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016410 xref: Reactome:1095 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003134 name: acylglycerol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016411 is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0003135 name: serine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016412 is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0003136 name: O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016413 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0003130 ! acetyltransferase activity [Term] id: CCO:F0003137 name: O-octanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0016414 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0003138 ! octanoyltransferase activity [Term] id: CCO:F0003138 name: octanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0016415 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003139 name: O-palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an palmitoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0016416 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0003132 ! palmitoyltransferase activity [Term] id: CCO:F0003140 name: S-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016417 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003141 name: S-acetyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016418 is_a: CCO:F0003130 ! acetyltransferase activity is_a: CCO:F0003140 ! S-acyltransferase activity [Term] id: CCO:F0003142 name: S-malonyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an malonyl group to a sulfur atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016419 is_a: CCO:F0003140 ! S-acyltransferase activity is_a: CCO:F0003143 ! malonyltransferase activity [Term] id: CCO:F0003143 name: malonyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an malonyl (HOOC-CH2-CO-) group to an acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016420 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003144 name: CoA carboxylase activity namespace: molecular_function subset: gosubset_prok xref: EC:6.4.1.- xref: GO:0016421 is_a: CCO:F0003443 ! ligase activity, forming carbon-carbon bonds [Term] id: CCO:F0003145 name: mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am." [EC:2.1.1.62] synonym: "messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase activity" EXACT [EC:2.1.1.62] synonym: "S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity" EXACT [EC:2.1.1.62] synonym: "S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity" EXACT [EC:2.1.1.62] xref: EC:2.1.1.62 xref: GO:0016422 xref: MetaCyc:2.1.1.62-RXN is_a: CCO:F0001761 ! mRNA methyltransferase activity [Term] id: CCO:F0003146 name: tRNA (guanine) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in a tRNA molecule." [GOC:mah] subset: gosubset_prok synonym: "tRNA (guanosine) methyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0016423 xref: GO:0016424 is_a: CCO:F0001762 ! tRNA methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003148 name: tRNA (adenine)-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an adenine residue in a tRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0016426 is_a: CCO:F0001762 ! tRNA methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003149 name: tRNA (cytosine)-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a cytosine residue in a tRNA molecule." [GOC:mah] xref: EC:2.1.1.- xref: GO:0016427 is_a: CCO:F0001762 ! tRNA methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003150 name: tRNA (cytosine-5-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine." [EC:2.1.1.29] synonym: "S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity" EXACT [EC:2.1.1.29] synonym: "transfer ribonucleate cytosine 5-methyltransferase activity" EXACT [EC:2.1.1.29] synonym: "transfer RNA cytosine 5-methyltransferase activity" EXACT [EC:2.1.1.29] xref: EC:2.1.1.29 xref: GO:0016428 xref: MetaCyc:TRNA-(CYTOSINE-5-)-METHYLTRANSFERASE-RXN is_a: CCO:F0003149 ! tRNA (cytosine)-methyltransferase activity [Term] id: CCO:F0003151 name: tRNA (adenine-N1-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine." [EC:2.1.1.36] subset: gosubset_prok synonym: "1-methyladenine transfer RNA methyltransferase activity" EXACT [EC:2.1.1.36] synonym: "adenine-1-methylase activity" EXACT [EC:2.1.1.36] synonym: "S-adenosyl-L-methionine:tRNA (adenine-1-N-)-methyltransferase activity" EXACT [EC:2.1.1.36] synonym: "S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase activity" EXACT [EC:2.1.1.36] synonym: "transfer ribonucleate adenine 1-methyltransferase activity" EXACT [EC:2.1.1.36] synonym: "transfer RNA (adenine-1) methyltransferase activity" EXACT [EC:2.1.1.36] xref: EC:2.1.1.36 xref: GO:0016429 xref: MetaCyc:TRNA-(ADENINE-N1-)-METHYLTRANSFERASE-RXN is_a: CCO:F0003148 ! tRNA (adenine)-methyltransferase activity [Term] id: CCO:F0003152 name: tRNA (adenine-N6-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine." [EC:2.1.1.55] synonym: "S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase activity" EXACT [EC:2.1.1.55] synonym: "S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase activity" EXACT [EC:2.1.1.55] xref: EC:2.1.1.55 xref: GO:0016430 xref: MetaCyc:TRNA-(ADENINE-N6-)-METHYLTRANSFERASE-RXN is_a: CCO:F0003148 ! tRNA (adenine)-methyltransferase activity [Term] id: CCO:F0003154 name: tRNA-uridine aminocarboxypropyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine." [EC:2.5.1.25] synonym: "S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase activity" EXACT [EC:2.5.1.25] xref: EC:2.5.1.25 xref: GO:0016432 xref: MetaCyc:2.5.1.25-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0003155 name: rRNA (adenine) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an adenine residue in an rRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0016433 is_a: CCO:F0002014 ! rRNA methyltransferase activity [Term] id: CCO:F0003156 name: rRNA (cytosine) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a cytosine residue in an rRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0016434 is_a: CCO:F0002014 ! rRNA methyltransferase activity [Term] id: CCO:F0003157 name: rRNA (guanine) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a guanine residue in an rRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0016435 is_a: CCO:F0002014 ! rRNA methyltransferase activity [Term] id: CCO:F0003158 name: rRNA (uridine) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a uridine residue in an rRNA molecule." [GOC:mah] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0016436 is_a: CCO:F0002014 ! rRNA methyltransferase activity [Term] id: CCO:F0003159 name: tRNA cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1)." [EC:2.7.7.21] synonym: "-C-C-A pyrophosphorylase" BROAD [EC:2.7.7.21] synonym: "ATP (CTP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.21] synonym: "ATP(CTP)-tRNA nucleotidyltransferase" BROAD [EC:2.7.7.21] synonym: "ATP(CTP):tRNA nucleotidyltransferase activity" EXACT [EC:2.7.7.21] synonym: "CTP(ATP):tRNA nucleotidyltransferase" BROAD [EC:2.7.7.21] synonym: "CTP:tRNA cytidylyltransferase activity" EXACT [] synonym: "ribonucleic cytidylic cytidylic adenylic pyrophosphorylase" BROAD [EC:2.7.7.21] synonym: "ribonucleic cytidylyltransferase" BROAD [EC:2.7.7.21] synonym: "transfer ribonucleate adenylyltransferase" BROAD [EC:2.7.7.21] synonym: "transfer ribonucleate cytidylyltransferase" BROAD [EC:2.7.7.21] synonym: "transfer ribonucleate nucleotidyltransferase" BROAD [EC:2.7.7.21] synonym: "transfer ribonucleic acid nucleotidyl transferase" BROAD [EC:2.7.7.21] synonym: "transfer ribonucleic adenylyl (cytidylyl) transferase" BROAD [EC:2.7.7.21] synonym: "transfer ribonucleic-terminal trinucleotide nucleotidyltransferase" BROAD [EC:2.7.7.21] synonym: "transfer RNA adenylyltransferase" BROAD [EC:2.7.7.21] synonym: "transfer-RNA nucleotidyltransferase" BROAD [EC:2.7.7.21] synonym: "tRNA adenylyl(cytidylyl)transferase" BROAD [EC:2.7.7.21] synonym: "tRNA CCA-diphosphorylase activity" RELATED [EC:2.7.7.21] synonym: "tRNA CCA-pyrophosphorylase activity" RELATED [EC:2.7.7.21] xref: EC:2.7.7.21 xref: GO:0016437 xref: MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0003160 name: tRNA-queuosine beta-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine." [EC:2.4.1.110] synonym: "GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity" EXACT [EC:2.4.1.110] xref: EC:2.4.1.110 xref: GO:0016438 xref: MetaCyc:2.4.1.110-RXN is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0003162 name: bidentate ribonuclease III activity namespace: molecular_function def: "Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference." [PMID:15242644] synonym: "bidentate RNase III activity" EXACT [] xref: EC:3.1.26.- xref: GO:0016443 is_a: CCO:F0000921 ! ribonuclease III activity [Term] id: CCO:F0003163 name: C-acetyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: GO:0016453 is_a: CCO:F0003130 ! acetyltransferase activity is_a: CCO:F0003131 ! C-acyltransferase activity [Term] id: CCO:F0003164 name: C-palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0016454 is_a: CCO:F0003131 ! C-acyltransferase activity is_a: CCO:F0003132 ! palmitoyltransferase activity [Term] id: CCO:F0003165 name: RNA polymerase II transcription mediator activity namespace: molecular_function def: "Functions to mediate the interaction of transcriptional activators with the RNA polymerase II-general RNA polymerase II transcription factor complex." [GOC:ma] synonym: "thyroid receptor-associated protein" RELATED [] synonym: "TRAP protein" RELATED [] xref: GO:0016455 is_a: CCO:F0003090 ! general RNA polymerase II transcription factor activity [Term] id: CCO:F0003166 name: pyrophosphatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments." [EC:3.6.1.-, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok xref: EC:3.6.1.- xref: GO:0016462 xref: Reactome:3222 is_a: CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Term] id: CCO:F0003167 name: zinc-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) = ADP + phosphate + Zn2+(out)." [EC:3.6.3.5] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "AtHMA4" RELATED [EC:3.6.3.5] synonym: "ATP phosphohydrolase (Zn2+-exporting)" EXACT [EC:3.6.3.5] synonym: "P(1B)-type ATPase activity" NARROW [EC:3.6.3.5] synonym: "P1B-type ATPase activity" EXACT [EC:3.6.3.5] synonym: "zinc exporting ATPase activity" EXACT [] synonym: "zinc-translocating P-type ATPase activity" BROAD [EC:3.6.3.5] synonym: "Zn(2+)-exporting ATPase activity" EXACT [EC:3.6.3.5] synonym: "Zn(II)-translocating P-type ATPase activity" EXACT [EC:3.6.3.5] synonym: "Zn2+-exporting ATPase activity" EXACT [EC:3.6.3.5] synonym: "zn2+-exporting ATPase activity" EXACT [EC:3.6.3.5] xref: EC:3.6.3.5 xref: GO:0016463 xref: MetaCyc:3.6.3.5-RXN is_a: CCO:F0001601 ! zinc ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0003168 name: chloroplast protein-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma." [EC:3.6.3.52] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (chloroplast protein-importing)" EXACT [EC:3.6.3.52] synonym: "chloroplast protein ABC transporter" NARROW [] xref: EC:3.6.3.52 xref: GO:0016464 xref: MetaCyc:3.6.3.52-RXN is_a: CCO:F0002869 ! protein-transmembrane transporting ATPase activity [Term] id: CCO:F0003169 name: tryptophan hydroxylase activator activity namespace: molecular_function def: "Increases the activity of the enzyme tryptophase hydroxylase." [GOC:ai] xref: GO:0016483 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0003170 name: proprotein convertase 2 activator activity namespace: molecular_function def: "Required for the maturation and activation of proprotein convertase 2." [GOC:ma, PMID:10749852] xref: GO:0016484 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0003171 name: structural constituent of peritrophic membrane namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents." [GOC:mtg_sensu, ISBN:0879694238] synonym: "structural constituent of peritrophic matrix (sensu Insecta)" EXACT [] synonym: "structural constituent of peritrophic membrane (sensu Insecta)" EXACT [] xref: GO:0016490 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0003172 name: oxidoreductase activity namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced." [GOC:go_curators] comment: Note that enzymes of class EC:1.97.-.- should also be annotated to this term. subset: goslim_candida subset: goslim_goa subset: goslim_pir subset: goslim_yeast subset: gosubset_prok synonym: "oxidoreductase activity, acting on other substrates" NARROW [] synonym: "redox activity" EXACT [] xref: EC:1 xref: GO:0016491 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003173 name: neurotensin receptor activity, G-protein coupled namespace: molecular_function def: "G-protein coupled receptor for the tridecapeptide neurotensin. Associated with G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)." [UniProtKB:O95665] synonym: "G protein coupled neurotensin receptor activity" EXACT [] synonym: "G-protein coupled neurotensin receptor activity" EXACT [] synonym: "G-protein-coupled neurotensin receptor activity" EXACT [] synonym: "neurotensin receptor activity, G protein coupled" EXACT [] xref: GO:0016492 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0003174 name: C-C chemokine receptor activity namespace: molecular_function def: "Combining with a C-C chemokine to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif." [PMID:8662823] xref: GO:0016493 is_a: CCO:F0001292 ! chemokine receptor activity is_a: CCO:F0004223 ! C-C chemokine binding [Term] id: CCO:F0003175 name: C-X-C chemokine receptor activity namespace: molecular_function def: "Combining with a C-X-C chemokine to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif." [PMID:8662823] xref: GO:0016494 is_a: CCO:F0001292 ! chemokine receptor activity is_a: CCO:F0004224 ! C-X-C chemokine binding [Term] id: CCO:F0003176 name: C-X3-C chemokine receptor activity namespace: molecular_function def: "Combining with a C-X3-C chemokine to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif." [GOC:dph] xref: GO:0016495 is_a: CCO:F0001292 ! chemokine receptor activity is_a: CCO:F0004226 ! C-X3-C chemokine binding [Term] id: CCO:F0003177 name: substance P receptor activity namespace: molecular_function def: "Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0016496 is_a: CCO:F0001333 ! tachykinin receptor activity [Term] id: CCO:F0003178 name: substance K receptor activity namespace: molecular_function def: "Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "neurokinin A receptor activity" EXACT [] synonym: "neuromedin L receptor activity" EXACT [] xref: GO:0016497 is_a: CCO:F0001333 ! tachykinin receptor activity [Term] id: CCO:F0003179 name: neuromedin K receptor activity namespace: molecular_function def: "Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "neurokinin B receptor activity" EXACT [] xref: GO:0016498 is_a: CCO:F0001333 ! tachykinin receptor activity [Term] id: CCO:F0003180 name: orexin receptor activity namespace: molecular_function def: "Combining with orexin to initiate a change in cell activity." [GOC:ai] xref: GO:0016499 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0003181 name: protein-hormone receptor activity namespace: molecular_function def: "Combining with a protein hormone to initiate a change in cell activity." [GOC:mah] xref: GO:0016500 is_a: CCO:F0000141 ! rhodopsin-like receptor activity [Term] id: CCO:F0003182 name: prostacyclin receptor activity namespace: molecular_function def: "Combining with prostacyclin (PGI(2)) to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "PGI receptor activity" RELATED [] synonym: "PGI(2) receptor activity" EXACT [] synonym: "prostaglandin I receptor activity" EXACT [] xref: GO:0004959 xref: GO:0016501 is_a: CCO:F0001297 ! prostaglandin receptor activity [Term] id: CCO:F0003183 name: nucleotide receptor activity namespace: molecular_function def: "Combining with a nucleotide to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0016502 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0003184 name: pheromone receptor activity namespace: molecular_function def: "Combining with a pheromone to initiate a change in cell activity." [GOC:hjd, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0016503 is_a: CCO:F0001272 ! G-protein coupled receptor activity [Term] id: CCO:F0003185 name: protease activator activity namespace: molecular_function def: "Increases the activity of a protease, any enzyme catalyzes the hydrolysis peptide bonds." [GOC:ai] subset: gosubset_prok xref: GO:0016504 xref: Reactome:11526 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0003186 name: apoptotic protease activator activity namespace: molecular_function xref: GO:0016505 is_a: CCO:F0003185 ! protease activator activity [Term] id: CCO:F0003187 name: long-chain-enoyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O." [EC:4.2.1.74] synonym: "long-chain enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.74] synonym: "long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.74] xref: EC:4.2.1.74 xref: GO:0016508 xref: MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003188 name: long-chain-3-hydroxyacyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+. Acts most rapidly on derivatives with chain length 8 or 10." [EC:1.1.1.211] comment: Also see '3-hydroxyacyl-CoA dehydrogenase activity ; GO:0003857'. subset: gosubset_prok synonym: "beta-hydroxyacyl-CoA dehydrogenase activity" EXACT [EC:1.1.1.211] synonym: "LCHAD" RELATED [EC:1.1.1.211] synonym: "long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.211] synonym: "long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.211] xref: EC:1.1.1.211 xref: GO:0016509 xref: MetaCyc:1.1.1.211-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003189 name: endothelin-converting enzyme activity namespace: molecular_function subset: gosubset_prok xref: GO:0016511 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0003190 name: endothelin-converting enzyme 1 activity namespace: molecular_function def: "Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor." [EC:3.4.24.71] subset: gosubset_prok synonym: "ECE-1 activity" EXACT [EC:3.4.24.71] xref: EC:3.4.24.71 xref: GO:0016512 xref: MetaCyc:3.4.24.71-RXN is_a: CCO:F0003189 ! endothelin-converting enzyme activity [Term] id: CCO:F0003191 name: interleukin-13 receptor activity namespace: molecular_function def: "Combining with interleukin-13 to initiate a change in cell activity." [GOC:jl] synonym: "IL-13R" EXACT [] xref: GO:0016515 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004237 ! interleukin-13 binding [Term] id: CCO:F0003192 name: interleukin-12 receptor activity namespace: molecular_function def: "Combining with interleukin-12 to initiate a change in cell activity." [GOC:jl] synonym: "IL-12R" EXACT [] xref: GO:0016517 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004236 ! interleukin-12 binding [Term] id: CCO:F0003193 name: interleukin-14 receptor activity namespace: molecular_function def: "Combining with interleukin-14 to initiate a change in cell activity." [GOC:jl] synonym: "IL-14R" EXACT [] xref: GO:0016518 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004238 ! interleukin-14 binding [Term] id: CCO:F0003194 name: gastric inhibitory peptide receptor activity namespace: molecular_function def: "Combining with gastric inhibitory peptide to initiate a change in cell activity." [UniProtKB:P48546] xref: GO:0016519 is_a: CCO:F0000186 ! corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity [Term] id: CCO:F0003195 name: growth hormone-releasing hormone receptor activity namespace: molecular_function def: "Combining with growth hormone-releasing hormone to initiate a change in cell activity." [UniProtKB:P32082] xref: GO:0016520 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0003196 name: pituitary adenylate cyclase activating polypeptide activity namespace: molecular_function synonym: "pituitary adenylyl cyclase activating polypeptide activity" EXACT [] xref: GO:0016521 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0003197 name: latrotoxin receptor activity namespace: molecular_function def: "Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, to initiate a change in cell activity." [GOC:jl, PMID:10025961] synonym: "latrophilin" NARROW [] xref: GO:0016524 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0003198 name: brain-specific angiogenesis inhibitor activity namespace: molecular_function xref: GO:0016527 is_a: CCO:F0000183 ! secretin-like receptor activity [Term] id: CCO:F0003199 name: metallochaperone activity namespace: molecular_function def: "Assists in the delivery of metal ions to target proteins or compartments." [GOC:jl, PMID:11739376] subset: goslim_pir subset: gosubset_prok xref: GO:0016530 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0003200 name: copper chaperone activity namespace: molecular_function def: "Assists in the delivery of copper ions to target proteins or compartments." [PMID:10790544, PMID:11739376] xref: GO:0016531 is_a: CCO:F0001644 ! copper ion binding is_a: CCO:F0003199 ! metallochaperone activity [Term] id: CCO:F0003201 name: superoxide dismutase copper chaperone activity namespace: molecular_function def: "A copper chaperone specifically delivering copper to the Cu-Zn superoxide dismutase." [http://link.springer-ny.com/link/service/journals/00335/papers/0011005/00110409.html, PMID:9295278] comment: See also the molecular function term 'copper, zinc superoxide dismutase activity ; GO:0004785'. xref: GO:0016532 is_a: CCO:F0003200 ! copper chaperone activity [Term] id: CCO:F0003202 name: cyclin-dependent protein kinase 5 activator activity namespace: molecular_function synonym: "cyclin-dependent protein kinase 5 activator, intrinsic catalyst activity" EXACT [] xref: GO:0016534 xref: GO:0016535 is_a: CCO:F0004382 ! protein kinase activator activity [Term] id: CCO:F0003203 name: cyclin-dependent protein kinase 5 activator regulator activity namespace: molecular_function def: "Modulation of the activity of cyclin-dependent protein kinase 5 activator." [GOC:ai] synonym: "cyclin-dependent protein kinase 5 activator, intrinsic regulator activity" NARROW [] xref: GO:0016536 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0003204 name: cyclin-dependent protein kinase regulator activity namespace: molecular_function def: "Modulates the activity of a cyclin-dependent protein kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins." [GOC:rn, PMID:7877684, PMID:9442875] synonym: "cyclin" BROAD [] synonym: "cyclin-dependent protein kinase, intrinsic regulator activity" NARROW [] synonym: "G1/S-specific cyclin" NARROW [] synonym: "G2/M-specific cyclin" NARROW [] xref: EC:2.7.1.- xref: GO:0003751 xref: GO:0003752 xref: GO:0003753 xref: GO:0016538 is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0003205 name: transcription activator activity namespace: molecular_function def: "Any transcription regulator activity required for initiation or upregulation of transcription." [GOC:jl, ISBN:0124325653] subset: gosubset_prok synonym: "transcription activating factor" NARROW [] synonym: "transcriptional activator activity" EXACT [] xref: GO:0003710 xref: GO:0016563 xref: Reactome:9388 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0003206 name: transcription repressor activity namespace: molecular_function def: "Any transcription regulator activity that prevents or downregulates transcription." [GOC:mah] subset: gosubset_prok synonym: "negative transcriptional regulator activity" EXACT [] synonym: "transcriptional repressor activity" EXACT [] xref: GO:0016564 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0003207 name: general transcriptional repressor activity namespace: molecular_function def: "Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set." [GOC:mah] xref: GO:0016565 is_a: CCO:F0003206 ! transcription repressor activity [Term] id: CCO:F0003208 name: specific transcriptional repressor activity namespace: molecular_function def: "Any activity that stops or downregulates transcription of specific genes or sets of genes." [GOC:mah] subset: gosubset_prok xref: GO:0016566 is_a: CCO:F0003206 ! transcription repressor activity [Term] id: CCO:F0003209 name: glycine binding namespace: molecular_function def: "Interacting selectively with glycine, aminoethanoic acid." [GOC:ai] synonym: "aminoacetic acid binding" EXACT [] synonym: "aminoethanoic acid binding" EXACT [] synonym: "Gly binding" EXACT [] xref: GO:0016594 is_a: CCO:F0003212 ! amino acid binding [Term] id: CCO:F0003210 name: glutamate binding namespace: molecular_function def: "Interacting selectively with glutamate, the anion of 2-aminopentanedioic acid." [GOC:ai] synonym: "glutamic acid binding" EXACT [] xref: GO:0016595 is_a: CCO:F0003212 ! amino acid binding [Term] id: CCO:F0003211 name: thienylcyclohexylpiperidine binding namespace: molecular_function def: "Interacting selectively with thienylcyclohexylpiperidine." [GOC:jl] synonym: "TCP binding" BROAD [] xref: GO:0016596 is_a: CCO:F0001746 ! drug binding [Term] id: CCO:F0003212 name: amino acid binding namespace: molecular_function def: "Interacting selectively with an amino acid, organic acids containing one or more amino substituents." [GOC:ai] subset: goslim_pir subset: gosubset_prok xref: GO:0016597 is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0003213 name: glutaminyl-peptide cyclotransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3." [EC:2.3.2.5] subset: gosubset_prok synonym: "glutaminyl cyclase activity" EXACT [EC:2.3.2.5] synonym: "glutaminyl-transfer ribonucleate cyclotransferase activity" EXACT [EC:2.3.2.5] synonym: "glutaminyl-tRNA cyclotransferase activity" NARROW [EC:2.3.2.5] synonym: "L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing)" EXACT [EC:2.3.2.5] xref: EC:2.3.2.5 xref: GO:0016603 xref: MetaCyc:GLUTAMINYL-PEPTIDE-CYCLOTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0003214 name: growth hormone-releasing hormone activity namespace: molecular_function xref: GO:0016608 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0003215 name: G-protein coupled serotonin receptor activity namespace: molecular_function synonym: "G protein coupled serotonin receptor activity" EXACT [] synonym: "G-protein-coupled serotonin receptor activity" EXACT [] xref: GO:0016609 is_a: CCO:F0001331 ! serotonin receptor activity [Term] id: CCO:F0003216 name: oxidoreductase activity, acting on CH-OH group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.1.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on the CH-OH group of donors, other acceptors" NARROW [] xref: EC:1.1 xref: GO:0016614 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003217 name: malate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate." [GOC:mah, ISBN:0582227089] subset: gosubset_prok xref: GO:0016615 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003218 name: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai] subset: gosubset_prok xref: EC:1.1.1 xref: GO:0016616 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003219 name: 4-oxoproline reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+." [EC:1.1.1.104] synonym: "4-hydroxy-L-proline:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.104] synonym: "hydroxy-L-proline oxidase activity" EXACT [] synonym: "hydroxyproline oxidase activity" EXACT [EC:1.1.1.104] xref: EC:1.1.1.104 xref: GO:0016617 xref: MetaCyc:4-OXOPROLINE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003220 name: hydroxypyruvate reductase activity namespace: molecular_function def: "Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+." [EC:1.1.1.81] subset: gosubset_prok synonym: "beta-hydroxypyruvate reductase activity" EXACT [EC:1.1.1.81] synonym: "D-glycerate dehydrogenase activity" EXACT [EC:1.1.1.81] synonym: "D-glycerate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.81] synonym: "NADH:hydroxypyruvate reductase activity" EXACT [EC:1.1.1.81] xref: EC:1.1.1.81 xref: GO:0016618 xref: MetaCyc:HYDROXYPYRUVATE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003221 name: malate dehydrogenase (oxaloacetate-decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. Also decarboxylates oxaloacetate." [EC:1.1.1.38] subset: gosubset_prok synonym: "'malic' enzyme" RELATED [EC:1.1.1.38] synonym: "(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)" EXACT [EC:1.1.1.38] synonym: "NAD-linked malic enzyme" RELATED [EC:1.1.1.38] synonym: "NAD-malic enzyme activity" BROAD [EC:1.1.1.38] synonym: "NAD-specific malic enzyme" RELATED [EC:1.1.1.38] xref: EC:1.1.1.38 xref: GO:0004472 xref: GO:0016619 xref: MetaCyc:MALIC-NAD-RXN is_a: CCO:F0000869 ! malic enzyme activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003222 name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] subset: gosubset_prok xref: EC:1.2.1 xref: GO:0016620 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003223 name: cinnamoyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+." [EC:1.2.1.44] synonym: "cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)" EXACT [EC:1.2.1.44] synonym: "cinnamoyl CoA reductase activity" EXACT [] synonym: "cinnamoyl-CoA:NADPH reductase activity" EXACT [EC:1.2.1.44] synonym: "cinnamoyl-coenzyme A reductase activity" EXACT [EC:1.2.1.44] synonym: "feruloyl coenzyme A reductase activity" EXACT [EC:1.2.1.44] synonym: "feruloyl-CoA reductase activity" EXACT [EC:1.2.1.44] synonym: "ferulyl-CoA reductase activity" EXACT [EC:1.2.1.44] synonym: "p-hydroxycinnamoyl coenzyme A reductase activity" EXACT [EC:1.2.1.44] xref: EC:1.2.1.44 xref: GO:0016621 xref: MetaCyc:CINNAMOYL-COA-REDUCTASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003224 name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] subset: gosubset_prok xref: EC:1.2.2 xref: GO:0016622 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003225 name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] subset: gosubset_prok xref: EC:1.2.3 xref: GO:0016623 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003226 name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor" EXACT [] xref: EC:1.2.4 xref: GO:0016624 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003227 name: oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor" EXACT [] xref: EC:1.2.7 xref: GO:0016625 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003228 name: oxidoreductase activity, acting on the CH-CH group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.3.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on the CH-CH group of donors, other acceptors" NARROW [] xref: EC:1.3 xref: GO:0016627 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003229 name: oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] subset: gosubset_prok xref: EC:1.3.1 xref: GO:0016628 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003230 name: 12-oxophytodienoate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 8-((1R,2R)-3-oxo-2-((Z)-pent-2-enyl)cyclopentyl)octanoate + NADP+ = (15Z)-12-oxophyto-10,15-dienoate + NADPH." [EC:1.3.1.42] synonym: "12-oxo-phytodienoate reductase activity" EXACT [] synonym: "12-oxo-phytodienoic acid reductase activity" EXACT [EC:1.3.1.42] synonym: "8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase activity" EXACT [EC:1.3.1.42] xref: EC:1.3.1.42 xref: GO:0016629 xref: MetaCyc:12-OXOPHYTODIENOATE-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003231 name: protochlorophyllide reductase activity namespace: molecular_function def: "Catalysis of the reaction: chlorophyllide A + NADP+ = protochlorophyllide + NADPH + H+." [EC:1.3.1.33] subset: gosubset_prok synonym: "chlorophyllide-a:NADP+ 7,8-oxidoreductase activity" EXACT [EC:1.3.1.33] synonym: "NADPH-protochlorophyllide oxidoreductase activity" EXACT [EC:1.3.1.33] synonym: "NADPH-protochlorophyllide reductase activity" EXACT [EC:1.3.1.33] synonym: "NADPH2-protochlorophyllide oxidoreductase activity" EXACT [EC:1.3.1.33] synonym: "protochlorophyllide oxidoreductase activity" EXACT [EC:1.3.1.33] synonym: "protochlorophyllide photooxidoreductase activity" EXACT [EC:1.3.1.33] xref: EC:1.3.1.33 xref: GO:0016630 xref: MetaCyc:PROTOCHLOROPHYLLIDE-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003232 name: enoyl-[acyl-carrier-protein] reductase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+." [EC:1.3.1.9, GOC:rb] subset: gosubset_prok synonym: "acyl-ACP dehydrogenase activity" EXACT [EC:1.3.1.-] synonym: "enoyl-[acyl-carrier protein] reductase activity" EXACT [] synonym: "enoyl-ACP reductase activity" EXACT [] synonym: "enoyl-acyl carrier protein reductase" EXACT [] xref: EC:1.3.1.- xref: GO:0016631 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003233 name: oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] xref: EC:1.3.2 xref: GO:0016632 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003234 name: galactonolactone dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c." [EC:1.3.2.3] synonym: "GLDase activity" EXACT [EC:1.3.2.3] synonym: "GLDHase activity" EXACT [EC:1.3.2.3] synonym: "L-galactono-1,4-lactone dehydrogenase activity" EXACT [] synonym: "L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.3.2.3] synonym: "L-galactono-gamma-lactone dehydrogenase activity" EXACT [EC:1.3.2.3] synonym: "L-galactono-gamma-lactone:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.3.2.3] synonym: "L-galactonolactone dehydrogenase activity" EXACT [EC:1.3.2.3] xref: EC:1.3.2.3 xref: GO:0016633 xref: MetaCyc:GALACTONOLACTONE-DEHYDROGENASE-RXN is_a: CCO:F0003233 ! oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor [Term] id: CCO:F0003235 name: oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] subset: gosubset_prok xref: EC:1.3.3 xref: GO:0016634 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003236 name: oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound." [GOC:jl] subset: gosubset_prok xref: EC:1.3.5 xref: GO:0016635 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003237 name: oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor" EXACT [] xref: EC:1.3.7 xref: GO:0016636 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003238 name: oxidoreductase activity, acting on the CH-NH2 group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.4.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors" NARROW [] xref: EC:1.4 xref: GO:0016638 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003239 name: oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai] subset: gosubset_prok xref: EC:1.4.1 xref: GO:0016639 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0003240 name: oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule." [GOC:ai] xref: EC:1.4.2 xref: GO:0016640 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0003241 name: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai] subset: gosubset_prok xref: EC:1.4.3 xref: GO:0016641 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0003242 name: oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group." [GOC:ai] subset: gosubset_prok synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor" EXACT [] xref: EC:1.4.4 xref: GO:0016642 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0003243 name: oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:ai] subset: gosubset_prok synonym: "oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor" EXACT [] xref: EC:1.4.7 xref: GO:0016643 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0003244 name: oxidoreductase activity, acting on the CH-NH group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.5.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on the CH-NH group of donors, other acceptors" NARROW [] xref: EC:1.5 xref: GO:0016645 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003245 name: oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] subset: gosubset_prok xref: EC:1.5.1 xref: GO:0016646 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003246 name: oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] subset: gosubset_prok xref: EC:1.5.3 xref: GO:0016647 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003247 name: oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide." [GOC:jl] synonym: "oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor" EXACT [] xref: EC:1.5.4 xref: GO:0016648 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003248 name: oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound." [GOC:jl] subset: gosubset_prok xref: EC:1.5.5 xref: GO:0016649 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003249 name: oxidoreductase activity, acting on NADH or NADPH namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.6.99.- should also be annotated to this term. subset: gosubset_prok synonym: "NAD(P)H dehydrogenase" NARROW [] synonym: "oxidoreductase activity, acting on NADH or NADPH, other acceptor" NARROW [] xref: EC:1.6 xref: GO:0016651 xref: Reactome:4134 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003250 name: oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai] subset: gosubset_prok xref: EC:1.6.1 xref: GO:0016652 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0003251 name: oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein." [GOC:ai] subset: gosubset_prok synonym: "oxidoreductase activity, acting on NADH or NADPH, haem protein as acceptor" EXACT [] xref: EC:1.6.2 xref: GO:0016653 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0003252 name: oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a disulfide group." [GOC:ai] subset: gosubset_prok synonym: "oxidoreductase activity, acting on NADH or NADPH, disulphide as acceptor" EXACT [] xref: EC:1.6.4 xref: GO:0016654 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0003253 name: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:1.6.5 xref: GO:0016655 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0003254 name: monodehydroascorbate reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate." [EC:1.6.5.4] synonym: "AFR" RELATED [EC:1.6.5.4] synonym: "AFR-reductase activity" EXACT [EC:1.6.5.4] synonym: "ascorbate free radical reductase activity" EXACT [EC:1.6.5.4] synonym: "ascorbate free-radical reductase activity" EXACT [EC:1.6.5.4] synonym: "ascorbic free radical reductase activity" EXACT [EC:1.6.5.4] synonym: "MDAsA reductase (NADPH)" EXACT [EC:1.6.5.4] synonym: "MDHA" RELATED [EC:1.6.5.4] synonym: "monodehydroascorbate reductase activity" EXACT [] synonym: "NADH-semidehydroascorbate oxidoreductase activity" EXACT [EC:1.6.5.4] synonym: "NADH:AFR oxidoreductase activity" EXACT [EC:1.6.5.4] synonym: "NADH:ascorbate radical oxidoreductase activity" EXACT [EC:1.6.5.4] synonym: "NADH:monodehydroascorbate oxidoreductase activity" EXACT [EC:1.6.5.4] synonym: "NADH:semidehydroascorbic acid oxidoreductase activity" EXACT [EC:1.6.5.4] synonym: "SDA reductase activity" EXACT [EC:1.6.5.4] synonym: "semidehydroascorbate reductase activity" EXACT [EC:1.6.5.4] xref: EC:1.6.5.4 xref: GO:0016656 xref: MetaCyc:1.6.5.4-RXN is_a: CCO:F0003253 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [Term] id: CCO:F0003255 name: oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group." [GOC:ai] subset: gosubset_prok xref: EC:1.6.6 xref: GO:0016657 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0003256 name: oxidoreductase activity, acting on other nitrogenous compounds as donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.7.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors" NARROW [] xref: EC:1.7 xref: GO:0016661 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003257 name: oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] subset: gosubset_prok xref: EC:1.7.2 xref: GO:0016662 is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0003258 name: oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] subset: gosubset_prok xref: EC:1.7.3 xref: GO:0016663 is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0003259 name: oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor" EXACT [] xref: EC:1.7.7 xref: GO:0016664 is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0003260 name: oxidoreductase activity, acting on sulfur group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.8.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on sulfur group of donors, other acceptors" NARROW [] synonym: "oxidoreductase activity, acting on sulphur group of donors" EXACT [] xref: EC:1.8 xref: GO:0016667 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003261 name: oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor" EXACT [] xref: EC:1.8.1 xref: GO:0016668 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003262 name: oxidoreductase activity, acting on sulfur group of donors, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor" EXACT [] xref: EC:1.8.2 xref: GO:0016669 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003263 name: oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor" EXACT [] xref: EC:1.8.3 xref: GO:0016670 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003264 name: oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor" EXACT [] xref: EC:1.8.4 xref: GO:0016671 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003265 name: oxidoreductase activity, acting on sulfur group of donors, quinone or similar compound as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor" EXACT [] xref: EC:1.8.5 xref: GO:0016672 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003266 name: oxidoreductase activity, acting on sulfur group of donors, iron-sulfur protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor" EXACT [] xref: EC:1.8.7 xref: GO:0016673 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003267 name: oxidoreductase activity, acting on heme group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.9.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on haem group of donors" EXACT [] synonym: "oxidoreductase activity, acting on heme group of donors, other acceptors" NARROW [] xref: EC:1.9 xref: GO:0016675 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003268 name: oxidoreductase activity, acting on heme group of donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on haem group of donors, oxygen as acceptor" EXACT [] xref: EC:1.9. xref: GO:0016676 is_a: CCO:F0003267 ! oxidoreductase activity, acting on heme group of donors [Term] id: CCO:F0003269 name: oxidoreductase activity, acting on heme group of donors, nitrogenous group as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group." [GOC:jl] synonym: "oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor" EXACT [] xref: EC:1.9.6 xref: GO:0016677 is_a: CCO:F0003267 ! oxidoreductase activity, acting on heme group of donors [Term] id: CCO:F0003270 name: oxidoreductase activity, acting on diphenols and related substances as donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.10.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors" NARROW [] xref: EC:1.10 xref: GO:0016679 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003271 name: oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] xref: EC:1.10.1 xref: GO:0016680 is_a: CCO:F0003270 ! oxidoreductase activity, acting on diphenols and related substances as donors [Term] id: CCO:F0003272 name: oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome." [GOC:jl] subset: gosubset_prok xref: EC:1.10.2 xref: GO:0016681 is_a: CCO:F0003270 ! oxidoreductase activity, acting on diphenols and related substances as donors [Term] id: CCO:F0003273 name: oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen." [GOC:jl] subset: gosubset_prok xref: EC:1.10.3 xref: GO:0016682 is_a: CCO:F0003270 ! oxidoreductase activity, acting on diphenols and related substances as donors [Term] id: CCO:F0003274 name: oxidoreductase activity, acting on peroxide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor." [GOC:ai] subset: gosubset_prok xref: EC:1.11 xref: GO:0016684 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003275 name: L-ascorbate peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-ascorbate + H2O2 = dehydroascorbate + 2 H2O." [EC:1.11.1.11] synonym: "ascorbate peroxidase activity" EXACT [EC:1.11.1.11] synonym: "ascorbic acid peroxidase activity" EXACT [EC:1.11.1.11] synonym: "L-ascorbate:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.11] synonym: "L-ascorbic acid peroxidase activity" EXACT [EC:1.11.1.11] synonym: "L-ascorbic acid-specific peroxidase activity" EXACT [EC:1.11.1.11] xref: EC:1.11.1.11 xref: GO:0016688 xref: MetaCyc:L-ASCORBATE-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0003276 name: manganese peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 Mn2+ + 2 H+ + H2O2 = 2 Mn3+ + 2 H2O." [EC:1.11.1.13] synonym: "Mn(II):hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.13] synonym: "Mn-dependent (NADH-oxidizing) peroxidase activity" EXACT [EC:1.11.1.13] synonym: "Mn-dependent peroxidase activity" EXACT [EC:1.11.1.13] synonym: "peroxidase-M2" RELATED [EC:1.11.1.13] xref: EC:1.11.1.13 xref: GO:0016689 xref: MetaCyc:MANGANESE-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0003277 name: diarylpropane peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol + H2O2 = veratraldehyde + 1-(3,4-dimethylphenyl)ethane-1,2-diol + 4 H2O." [EC:1.11.1.14] synonym: "1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.14] synonym: "diarylpropane oxygenase activity" EXACT [EC:1.11.1.14] synonym: "diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving)" EXACT [EC:1.11.1.14] synonym: "lignin peroxidase activity" EXACT [EC:1.11.1.14] synonym: "ligninase activity" EXACT [EC:1.11.1.14] synonym: "ligninase I activity" NARROW [EC:1.11.1.14] synonym: "LiP activity" NARROW [EC:1.11.1.14] xref: EC:1.11.1.14 xref: GO:0016690 xref: MetaCyc:DIARYLPROPANE-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0003278 name: chloride peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 R-H + 2 chloride + H2O2 = 2 R-Cl + 2 H2O." [EC:1.11.1.10] subset: gosubset_prok synonym: "chloride:hydrogen-peroxide oxidoreductase" EXACT [EC:1.11.1.10] synonym: "chloroperoxidase activity" EXACT [EC:1.11.1.10] synonym: "cofactor-free chloroperoxidase activity" NARROW [] synonym: "flavin-haem chloroperoxidase activity" NARROW [] synonym: "flavin-heme chloroperoxidase activity" NARROW [] synonym: "haem chloroperoxidase activity" NARROW [] synonym: "heme chloroperoxidase activity" NARROW [] synonym: "vanadium chloroperoxidase activity" NARROW [] xref: EC:1.11.1.10 xref: GO:0016691 xref: GO:0016955 xref: GO:0016956 xref: GO:0016957 xref: GO:0016958 xref: MetaCyc:CHLORIDE-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0003279 name: NADH peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + H2O2 = NAD+ + 2 H2O." [EC:1.11.1.1] subset: gosubset_prok synonym: "diphosphopyridine nucleotide peroxidase activity" EXACT [EC:1.11.1.1] synonym: "DPNH peroxidase activity" EXACT [EC:1.11.1.1] synonym: "NAD peroxidase activity" EXACT [EC:1.11.1.1] synonym: "NADH-peroxidase activity" EXACT [EC:1.11.1.1] synonym: "NADH:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.1] synonym: "nicotinamide adenine dinucleotide peroxidase activity" EXACT [EC:1.11.1.1] xref: EC:1.11.1.1 xref: GO:0016692 xref: MetaCyc:NADH-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0003280 name: secretory plant peroxidase activity namespace: molecular_function xref: EC:1.11.1.- xref: GO:0016693 is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0003281 name: oxidoreductase activity, acting on hydrogen as donor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor." [GOC:jl] comment: Note that enzymes of class EC:1.12.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on hydrogen as donor, other acceptors" NARROW [] xref: EC:1.12 xref: GO:0016695 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003282 name: oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP." [GOC:jl] subset: gosubset_prok xref: EC:1.12.1 xref: GO:0016696 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0003283 name: oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome." [GOC:jl] subset: gosubset_prok xref: EC:1.12.2 xref: GO:0016697 xref: GO:0016698 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0003284 name: oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein." [GOC:jl] subset: gosubset_prok synonym: "oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor" EXACT [] xref: EC:1.12.7 xref: GO:0016699 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0003285 name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor." [GOC:mah] comment: Note that enzymes of class EC:1.13.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous" NARROW [] synonym: "oxygenase" BROAD [] xref: EC:1.13 xref: GO:0016701 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003286 name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor." [GOC:mah] subset: gosubset_prok xref: EC:1.13.11 xref: GO:0016702 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is_a: CCO:F0008070 ! dioxygenase activity [Term] id: CCO:F0003287 name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor." [GOC:mah] subset: gosubset_prok xref: EC:1.13.12 xref: GO:0016703 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Term] id: CCO:F0003288 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor." [GOC:mah] comment: Note that enzymes of class EC:1.14.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous" NARROW [] xref: EC:1.14 xref: GO:0016705 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003289 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor." [GOC:mah] subset: gosubset_prok xref: EC:1.14.11 xref: GO:0016706 xref: Reactome:726 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003290 name: gibberellin 3-beta-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: gibberellin 20 + 2-oxoglutarate + O2 = gibberellin 1 + succinate + CO2." [EC:1.14.11.15] synonym: "(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)" EXACT [EC:1.14.11.15] synonym: "(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)" EXACT [EC:1.14.11.15] synonym: "gibberellin 3-beta-hydroxylase activity" EXACT [EC:1.14.11.15] synonym: "gibberellin 3beta-dioxygenase activity" EXACT [EC:1.14.11.15] synonym: "gibberellin 3beta-hydroxylase activity" EXACT [EC:1.14.11.15] xref: EC:1.14.11.15 xref: GO:0016707 xref: MetaCyc:GIBBERELLIN-3-BETA-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0003291 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor." [GOC:mah] subset: gosubset_prok xref: EC:1.14.12 xref: GO:0016708 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is_a: CCO:F0008070 ! dioxygenase activity [Term] id: CCO:F0003292 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] subset: gosubset_prok xref: EC:1.14.13 xref: GO:0016709 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003293 name: trans-cinnamate 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O." [EC:1.14.13.11] synonym: "CA4H activity" NARROW [EC:1.14.13.11] synonym: "cinnamate 4-hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "cinnamate 4-monooxygenase activity" EXACT [EC:1.14.13.11] synonym: "cinnamate hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "cinnamic 4-hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "cinnamic acid 4-hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "cinnamic acid 4-monooxygenase activity" EXACT [EC:1.14.13.11] synonym: "cinnamic acid p-hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "cytochrome P450 cinnamate 4-hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "hydroxylase, cinnamate 4-" EXACT [EC:1.14.13.11] synonym: "oxygenase, cinnamate 4-mono-" EXACT [EC:1.14.13.11] synonym: "t-cinnamic acid hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "trans-cinnamate 4-hydroxylase activity" EXACT [EC:1.14.13.11] synonym: "trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.13.11] synonym: "trans-cinnamic acid 4-hydroxylase activity" EXACT [EC:1.14.13.11] xref: EC:1.14.13.11 xref: GO:0016710 xref: MetaCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003294 name: flavonoid 3'-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O." [EC:1.14.13.21] synonym: "flavonoid 3'-hydroxylase activity" EXACT [EC:1.14.13.21] synonym: "flavonoid 3-hydroxylase (erroneous)" EXACT [EC:1.14.13.21] synonym: "flavonoid 3-monooxygenase (erroneous)" EXACT [EC:1.14.13.21] synonym: "flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.13.21] synonym: "NADPH:flavonoid-3'-hydroxylase activity" EXACT [EC:1.14.13.21] xref: EC:1.14.13.21 xref: GO:0016711 xref: MetaCyc:FLAVONOID-3 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003295 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] subset: gosubset_prok xref: EC:1.14.14 xref: GO:0016712 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003296 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] subset: gosubset_prok synonym: "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulphur protein as one donor, and incorporation of one atom of oxygen" EXACT [] xref: EC:1.14.15 xref: GO:0016713 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003297 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] subset: gosubset_prok xref: EC:1.14.16 xref: GO:0016714 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003298 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor." [GOC:mah] subset: gosubset_prok xref: EC:1.14.17 xref: GO:0016715 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003299 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor." [GOC:mah] subset: gosubset_prok xref: EC:1.14.18 xref: GO:0016716 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003300 name: oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water." [GOC:mah] subset: gosubset_prok xref: EC:1.14.19 xref: GO:0016717 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003301 name: carotene 7,8-desaturase activity namespace: molecular_function def: "Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O." [EC:1.14.99.30] subset: gosubset_prok synonym: "carotene,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.30] synonym: "zeta-carotene desaturase activity" EXACT [EC:1.14.99.30] xref: EC:1.14.99.30 xref: GO:0016719 xref: MetaCyc:1.14.99.30-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003302 name: delta12-fatty acid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: linoleate + donor-H2 + O2 = crepenynate + acceptor + H2O." [EC:1.14.99.33] synonym: "crepenynate synthase activity" NARROW [EC:1.14.99.33] synonym: "D12-fatty acid dehydrogenase activity" EXACT [] synonym: "delta-12 fatty acid acetylenase activity" EXACT [EC:1.14.99.33] synonym: "delta12 fatty acid acetylenase activity" EXACT [EC:1.14.99.33] synonym: "linoleate delta-12-fatty acid acetylenase (desaturase) activity" EXACT [] synonym: "linoleate delta12-fatty acid acetylenase (desaturase)" EXACT [EC:1.14.99.33] synonym: "linoleate, hydrogen-donor:oxygen oxidoreductase (Delta12-unsaturating)" EXACT [EC:1.14.99.33] xref: EC:1.14.99.33 xref: GO:0016720 xref: MetaCyc:1.14.99.33-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003303 name: oxidoreductase activity, acting on superoxide radicals as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor." [GOC:ai] subset: gosubset_prok xref: EC:1.15 xref: GO:0016721 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003304 name: oxidoreductase activity, oxidizing metal ions namespace: molecular_function def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered." [GOC:mah] subset: gosubset_prok xref: EC:1.16 xref: GO:0016722 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003305 name: oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor." [GOC:mah] subset: gosubset_prok xref: EC:1.16.1 xref: GO:0016723 is_a: CCO:F0003304 ! oxidoreductase activity, oxidizing metal ions [Term] id: CCO:F0003306 name: oxidoreductase activity, oxidizing metal ions, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor." [GOC:mah] subset: gosubset_prok xref: EC:1.16.3 xref: GO:0016724 is_a: CCO:F0003304 ! oxidoreductase activity, oxidizing metal ions [Term] id: CCO:F0003307 name: oxidoreductase activity, acting on CH or CH2 groups namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.17.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on CH or CH2 groups, other acceptors" NARROW [] xref: EC:1.17 xref: GO:0016725 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003308 name: oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP." [GOC:ai] subset: gosubset_prok xref: EC:1.17.1 xref: GO:0016726 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0003309 name: oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai] subset: gosubset_prok xref: EC:1.17.3 xref: GO:0016727 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0003310 name: oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group." [GOC:ai] subset: gosubset_prok synonym: "oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor" EXACT [] xref: EC:1.17.4 xref: GO:0016728 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0003311 name: oxidoreductase activity, acting on iron-sulfur proteins as donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] subset: gosubset_prok synonym: "oxidoreductase activity, acting on iron-sulphur proteins as donors" EXACT [] xref: EC:1.18 xref: GO:0016730 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003312 name: oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] subset: gosubset_prok xref: EC:1.18.1 xref: GO:0016731 is_a: CCO:F0003311 ! oxidoreductase activity, acting on iron-sulfur proteins as donors [Term] id: CCO:F0003313 name: oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen." [GOC:jl] subset: gosubset_prok xref: EC:1.18.6 xref: GO:0016732 is_a: CCO:F0003311 ! oxidoreductase activity, acting on iron-sulfur proteins as donors [Term] id: CCO:F0003314 name: oxidoreductase activity, acting on reduced flavodoxin as donor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] subset: gosubset_prok xref: EC:1.19 xref: GO:0016737 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003315 name: oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen." [GOC:jl] subset: gosubset_prok xref: EC:1.19.6 xref: GO:0016738 is_a: CCO:F0003314 ! oxidoreductase activity, acting on reduced flavodoxin as donor [Term] id: CCO:F0003316 name: transferase activity namespace: molecular_function def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: EC:2 xref: GO:0016740 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003317 name: transferase activity, transferring one-carbon groups namespace: molecular_function def: "Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:2.1 xref: GO:0016741 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003318 name: hydroxymethyl-, formyl- and related transferase activity namespace: molecular_function subset: gosubset_prok xref: EC:2.1.2 xref: GO:0016742 is_a: CCO:F0000791 ! glycine hydroxymethyltransferase activity [Term] id: CCO:F0003319 name: carboxyl- or carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor)." [GOC:jl] subset: gosubset_prok synonym: "carboxyl- and carbamoyltransferase activity" EXACT [] xref: EC:2.1.3 xref: GO:0016743 is_a: CCO:F0003317 ! transferase activity, transferring one-carbon groups [Term] id: CCO:F0003320 name: transferase activity, transferring aldehyde or ketonic groups namespace: molecular_function def: "Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "transketolase or transaldolase activity" EXACT [] xref: EC:2.2 xref: EC:2.2.1 xref: GO:0016744 xref: GO:0016745 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003321 name: transferase activity, transferring acyl groups namespace: molecular_function def: "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:2.3 xref: GO:0016746 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003322 name: transferase activity, transferring groups other than amino-acyl groups namespace: molecular_function def: "Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor)." [GOC:jl] subset: gosubset_prok xref: EC:2.3.1 xref: GO:0016747 xref: Reactome:1087 is_a: CCO:F0003321 ! transferase activity, transferring acyl groups [Term] id: CCO:F0003323 name: succinyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an succinyl (3-carboxypropanoyl) group to an acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016748 xref: Reactome:1089 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003324 name: N-succinyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an succinyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016749 is_a: CCO:F0003133 ! N-acyltransferase activity is_a: CCO:F0003323 ! succinyltransferase activity [Term] id: CCO:F0003325 name: O-succinyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an succinyl group to an oxygen atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016750 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0003323 ! succinyltransferase activity [Term] id: CCO:F0003326 name: S-succinyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an succinyl group to a sulfur atom on the acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0016751 is_a: CCO:F0003140 ! S-acyltransferase activity is_a: CCO:F0003323 ! succinyltransferase activity [Term] id: CCO:F0003327 name: sinapoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an sinapoyl group to an acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0016752 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003328 name: O-sinapoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an sinapoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0016753 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0003327 ! sinapoyltransferase activity [Term] id: CCO:F0003329 name: sinapoylglucose-malate O-sinapoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + (S)-malate = D-glucose + sinapoyl-(S)-malate." [EC:2.3.1.92] synonym: "1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase activity" EXACT [EC:2.3.1.92] synonym: "1-sinapoylglucose-L-malate sinapoyltransferase activity" EXACT [EC:2.3.1.92] synonym: "sinapoylglucose:malate sinapoyltransferase activity" EXACT [] xref: EC:2.3.1.92 xref: GO:0016754 xref: MetaCyc:2.3.1.92-RXN is_a: CCO:F0003328 ! O-sinapoyltransferase activity [Term] id: CCO:F0003330 name: transferase activity, transferring amino-acyl groups namespace: molecular_function def: "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)." [GOC:jl] subset: gosubset_prok synonym: "aminoacyltransferase activity" EXACT [] xref: EC:2.3.2 xref: GO:0016755 is_a: CCO:F0003321 ! transferase activity, transferring acyl groups [Term] id: CCO:F0003331 name: glutathione gamma-glutamylcysteinyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly." [EC:2.3.2.15] synonym: "gamma-glutamylcysteine dipeptidyl transpeptidase activity" EXACT [EC:2.3.2.15] synonym: "glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase activity" EXACT [EC:2.3.2.15] synonym: "phytochelatin synthase activity" EXACT [EC:2.3.2.15] xref: EC:2.3.2.15 xref: GO:0016756 xref: GO:0042143 xref: MetaCyc:2.3.2.15-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0003332 name: transferase activity, transferring glycosyl groups namespace: molecular_function def: "Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that enzymes of class EC:2.4.99.- should also be annotated to this term. subset: gosubset_prok synonym: "glycosyltransferase activity" EXACT [] synonym: "transferase activity, transferring other glycosyl groups" NARROW [] synonym: "transglycosylase activity" EXACT [] xref: EC:2.4 xref: GO:0016757 xref: GO:0016932 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003333 name: transferase activity, transferring hexosyl groups namespace: molecular_function def: "Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor)." [GOC:jl] subset: gosubset_prok synonym: "hexosyltransferase activity" EXACT [] xref: EC:2.4.1 xref: GO:0016758 is_a: CCO:F0003332 ! transferase activity, transferring glycosyl groups [Term] id: CCO:F0003334 name: cellulose synthase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1)." [EC:2.4.1.12, EC:2.4.1.29] subset: gosubset_prok synonym: "cellulose synthetase activity" EXACT [EC:2.4.1.29] xref: EC:2.4.1.- xref: GO:0016759 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0003335 name: cellulose synthase (UDP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1)." [EC:2.4.1.12] subset: gosubset_prok synonym: "1,4-beta-D-glucan synthase activity" EXACT [EC:2.4.1.12] synonym: "1,4-beta-glucan synthase activity" EXACT [EC:2.4.1.12] synonym: "beta-1,4-glucan synthase activity" EXACT [EC:2.4.1.12] synonym: "beta-1,4-glucan synthetase activity" EXACT [EC:2.4.1.12] synonym: "beta-1,4-glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "beta-glucan synthase activity" EXACT [EC:2.4.1.12] synonym: "glucan synthase activity" EXACT [EC:2.4.1.12] synonym: "GS-I" RELATED [EC:2.4.1.12] synonym: "UDP-glucose-1,4-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "UDP-glucose-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "UDP-glucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "UDPglucose-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "UDPglucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "uridine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.12] synonym: "uridine diphosphoglucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.12] xref: EC:2.4.1.12 xref: GO:0016760 xref: MetaCyc:CELLULOSE-SYNTHASE-(UDP-FORMING)-RXN is_a: CCO:F0003334 ! cellulose synthase activity is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0003336 name: cellulose synthase (GDP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1)." [EC:2.4.1.29] synonym: "cellulose synthase (guanosine diphosphate-forming) activity" EXACT [EC:2.4.1.29] synonym: "GDP-glucose-beta-D-glucan glucosyltransferase activity" EXACT [EC:2.4.1.29] synonym: "GDP-glucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.29] synonym: "GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.29] synonym: "GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.29] synonym: "guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity" EXACT [EC:2.4.1.29] synonym: "guanosine diphosphoglucose-cellulose glucosyltransferase activity" EXACT [EC:2.4.1.29] xref: EC:2.4.1.29 xref: GO:0016761 xref: MetaCyc:CELLULOSE-SYNTHASE-(GDP-FORMING)-RXN is_a: CCO:F0003334 ! cellulose synthase activity [Term] id: CCO:F0003337 name: xyloglucan:xyloglucosyl transferase activity namespace: molecular_function def: "Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan." [EC:2.4.1.207] synonym: "endo-xyloglucan transferase activity" EXACT [EC:2.4.1.207] synonym: "endoxyloglucan transferase activity" EXACT [] synonym: "xyloglucan endotransglycosylase activity" EXACT [EC:2.4.1.207] synonym: "xyloglucan:xyloglucan xyloglucanotransferase activity" EXACT [EC:2.4.1.207] xref: EC:2.4.1.207 xref: GO:0016762 xref: MetaCyc:2.4.1.207-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0003338 name: transferase activity, transferring pentosyl groups namespace: molecular_function def: "Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor)." [GOC:jl] subset: gosubset_prok synonym: "pentosyltransferase activity" EXACT [] xref: EC:2.4.2 xref: GO:0016763 xref: Reactome:1245 is_a: CCO:F0003332 ! transferase activity, transferring glycosyl groups [Term] id: CCO:F0003339 name: transferase activity, transferring alkyl or aryl (other than methyl) groups namespace: molecular_function def: "Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "transferase activity, transferring alkyl or aryl groups, other than methyl groups" EXACT [] xref: EC:2.5 xref: GO:0016765 xref: GO:0016766 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003340 name: geranylgeranyl-diphosphate geranylgeranyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate." [EC:2.5.1.32] subset: gosubset_prok synonym: "geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.32] synonym: "phytoene synthetase activity" EXACT [EC:2.5.1.32] synonym: "prephytoene-diphosphate synthase activity" EXACT [EC:2.5.1.32] synonym: "PSase activity" EXACT [EC:2.5.1.32] xref: EC:2.5.1.32 xref: GO:0016767 xref: MetaCyc:2.5.1.32-RXN is_a: CCO:F0000756 ! geranyltranstransferase activity [Term] id: CCO:F0003341 name: spermine synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine." [EC:2.5.1.22] synonym: "S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity" EXACT [EC:2.5.1.22] synonym: "spermidine aminopropyltransferase activity" EXACT [EC:2.5.1.22] synonym: "spermine synthetase activity" EXACT [EC:2.5.1.22] xref: EC:2.5.1.22 xref: GO:0016768 xref: MetaCyc:SPERMINE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0003342 name: transferase activity, transferring nitrogenous groups namespace: molecular_function def: "Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that enzymes of class EC:2.6.99.- should also be annotated to this term. subset: gosubset_prok synonym: "transferase activity, transferring other nitrogenous groups" NARROW [] xref: EC:2.6 xref: GO:0016769 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003343 name: oximinotransaminase activity namespace: molecular_function def: "Catalysis of the reversible transfer of an oxime group to an acceptor." [GOC:ai] xref: EC:2.6.3 xref: GO:0016770 is_a: CCO:F0003342 ! transferase activity, transferring nitrogenous groups [Term] id: CCO:F0003344 name: transferase activity, transferring phosphorus-containing groups namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides. subset: gosubset_prok xref: EC:2.7 xref: GO:0016772 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003345 name: phosphotransferase activity, alcohol group as acceptor namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor)." [GOC:jl] subset: gosubset_prok xref: EC:2.7.1 xref: GO:0016773 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003346 name: phosphotransferase activity, carboxyl group as acceptor namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor)." [GOC:jl] subset: gosubset_prok xref: EC:2.7.2 xref: GO:0016774 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003347 name: phosphotransferase activity, nitrogenous group as acceptor namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor)." [GOC:jl] subset: gosubset_prok xref: EC:2.7.3 xref: GO:0016775 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003348 name: phosphotransferase activity, phosphate group as acceptor namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor)." [GOC:jl] subset: gosubset_prok xref: EC:2.7.4 xref: GO:0016776 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003349 name: phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers namespace: molecular_function xref: EC:2.7.5 xref: GO:0016777 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0003350 name: diphosphotransferase activity namespace: molecular_function def: "Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor)." [GOC:jl, http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/intro.html] subset: gosubset_prok xref: EC:2.7.6 xref: GO:0016778 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003351 name: nucleotidyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a nucleotidyl group to a reactant." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_yeast subset: gosubset_prok xref: EC:2.7.7 xref: GO:0016779 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003352 name: phosphotransferase activity, for other substituted phosphate groups namespace: molecular_function def: "Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor)." [GOC:jl, http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/intro.html] subset: gosubset_prok xref: EC:2.7.8 xref: GO:0016780 xref: Reactome:1452 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003353 name: phosphotransferase activity, paired acceptors namespace: molecular_function def: "Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors." [GOC:jl, http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/intro.html] subset: gosubset_prok xref: EC:2.7.9 xref: GO:0016781 is_a: CCO:F0003344 ! transferase activity, transferring phosphorus-containing groups [Term] id: CCO:F0003354 name: transferase activity, transferring sulfur-containing groups namespace: molecular_function def: "Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "transferase activity, transferring sulphur-containing groups" EXACT [] xref: EC:2.8 xref: GO:0016782 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003355 name: sulfurtransferase activity namespace: molecular_function def: "Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor)." [GOC:ai, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok synonym: "sulphurtransferase activity" EXACT [] xref: EC:2.8.1 xref: GO:0016783 is_a: CCO:F0003354 ! transferase activity, transferring sulfur-containing groups [Term] id: CCO:F0003356 name: 3-mercaptopyruvate sulfurtransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate." [EC:2.8.1.2] subset: gosubset_prok synonym: "3-mercaptopyruvate sulphurtransferase activity" EXACT [] synonym: "3-mercaptopyruvate:cyanide sulfurtransferase activity" EXACT [EC:2.8.1.2] synonym: "beta-mercaptopyruvate sulfurtransferase activity" EXACT [EC:2.8.1.2] synonym: "mercaptopyruvate sulfurtransferase activity" EXACT [] xref: EC:2.8.1.2 xref: GO:0016784 xref: MetaCyc:MERCAPYSTRANS-RXN is_a: CCO:F0003355 ! sulfurtransferase activity [Term] id: CCO:F0003357 name: transferase activity, transferring selenium-containing groups namespace: molecular_function def: "Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:2.9 xref: GO:0016785 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0003358 name: selenotransferase activity namespace: molecular_function subset: gosubset_prok xref: EC:2.9.1 xref: GO:0016786 is_a: CCO:F0003357 ! transferase activity, transferring selenium-containing groups [Term] id: CCO:F0003359 name: hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok xref: EC:3 xref: GO:0016787 xref: Reactome:450 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003360 name: hydrolase activity, acting on ester bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any ester bond." [GOC:jl] subset: gosubset_prok synonym: "esterase activity" EXACT [] xref: EC:3.1 xref: GO:0016788 xref: Reactome:448 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003361 name: thiolester hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A." [http://www.onelook.com] subset: gosubset_prok synonym: "thiolesterase activity" EXACT [] xref: EC:3.1.2 xref: GO:0016790 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0003363 name: triphosphoric monoester hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group." [GOC:ai] subset: gosubset_prok xref: EC:3.1.5 xref: GO:0016793 is_a: CCO:F0005685 ! phosphoric ester hydrolase activity [Term] id: CCO:F0003364 name: diphosphoric monoester hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group." [GOC:ai] subset: gosubset_prok xref: EC:3.1.7 xref: GO:0016794 is_a: CCO:F0005685 ! phosphoric ester hydrolase activity [Term] id: CCO:F0003365 name: phosphoric triester hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a phosphoric triester." [http://cancerweb.ncl.ac.uk/] xref: EC:3.1.8 xref: GO:0016795 is_a: CCO:F0005685 ! phosphoric ester hydrolase activity [Term] id: CCO:F0003366 name: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters." [GOC:mah] comment: Note that this activity can catalyze cleavage of DNA or RNA. subset: gosubset_prok synonym: "exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters" EXACT [] xref: EC:3.1.15 xref: GO:0016796 is_a: CCO:F0000923 ! exonuclease activity [Term] id: CCO:F0003367 name: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters." [GOC:mah] comment: Note that this activity can catalyze cleavage of DNA or RNA. subset: gosubset_prok xref: EC:3.1.16 xref: GO:0016797 is_a: CCO:F0000923 ! exonuclease activity [Term] id: CCO:F0003368 name: hydrolase activity, acting on glycosyl bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any glycosyl bond." [GOC:jl] subset: gosubset_prok synonym: "glycosylase" NARROW [] synonym: "N-glycosylase" NARROW [] xref: EC:3.2 xref: GO:0016798 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003369 name: hydrolase activity, hydrolyzing N-glycosyl compounds namespace: molecular_function def: "Catalysis of the hydrolysis of any N-glycosyl bond." [GOC:jl] subset: gosubset_prok xref: EC:3.2.2 xref: GO:0016799 is_a: CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds [Term] id: CCO:F0003370 name: hydrolase activity, hydrolyzing S-glycosyl compounds namespace: molecular_function def: "Catalysis of the hydrolysis of any S-glycosyl bond." [GOC:mah] xref: EC:3.2.3.- xref: GO:0016800 is_a: CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds [Term] id: CCO:F0003371 name: hydrolase activity, acting on ether bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively." [GOC:ai, GOC:jl] subset: gosubset_prok xref: EC:3.3 xref: GO:0016801 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003372 name: trialkylsulfonium hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a thioether bond, -S-." [EC:3.3.1.-, GOC:ai] subset: gosubset_prok synonym: "thioether hydrolase activity" EXACT [] synonym: "trialkylsulphonium hydrolase activity" EXACT [] xref: EC:3.3.1.- xref: GO:0016802 is_a: CCO:F0003371 ! hydrolase activity, acting on ether bonds [Term] id: CCO:F0003373 name: ether hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of an ether bond, -O-." [EC:3.3.2.-, GOC:ai] subset: gosubset_prok xref: EC:3.3.2 xref: GO:0016803 is_a: CCO:F0003371 ! hydrolase activity, acting on ether bonds [Term] id: CCO:F0003374 name: prolyl aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of a N-terminal proline from a peptide." [EC:3.4.11.5] subset: gosubset_prok synonym: "cytosol aminopeptidase V" RELATED [EC:3.4.11.5] synonym: "Pro-X aminopeptidase activity" EXACT [EC:3.4.11.5] synonym: "proline aminopeptidase" BROAD [EC:3.4.11.5] synonym: "proline iminopeptidase activity" EXACT [] xref: EC:3.4.11.5 xref: GO:0016804 xref: MetaCyc:3.4.11.5-RXN is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0003375 name: dipeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a dipeptide." [http://www.onelook.com] subset: gosubset_prok xref: EC:3.4.13 xref: GO:0016805 is_a: CCO:F0001788 ! exopeptidase activity [Term] id: CCO:F0003376 name: dipeptidyl-peptidase and tripeptidyl-peptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain." [GOC:ai] subset: gosubset_prok xref: EC:3.4.14 xref: GO:0016806 is_a: CCO:F0001788 ! exopeptidase activity [Term] id: CCO:F0003377 name: cysteine-type carboxypeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of carboxyl terminal peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center." [EC:3.4.18.-, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: EC:3.4.18 xref: GO:0016807 is_a: CCO:F0000649 ! carboxypeptidase activity is_a: CCO:F0001784 ! cysteine-type peptidase activity [Term] id: CCO:F0003378 name: proprotein convertase activity namespace: molecular_function xref: EC:3.4.21.- xref: GO:0016808 is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0003379 name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds." [GOC:jl] comment: Note that enzymes of class EC:3.5.99.- should also be annotated to this term. subset: gosubset_prok synonym: "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds" NARROW [] xref: EC:3.5 xref: GO:0016810 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003380 name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides namespace: molecular_function def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide." [GOC:ai] subset: gosubset_prok xref: EC:3.5.1 xref: GO:0016811 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0003381 name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides namespace: molecular_function def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide." [GOC:ai] subset: gosubset_prok xref: EC:3.5.2 xref: GO:0016812 xref: Reactome:2753 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0003382 name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines namespace: molecular_function def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:3.5.3 xref: GO:0016813 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0003383 name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines namespace: molecular_function def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:3.5.4 xref: GO:0016814 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0003384 name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles namespace: molecular_function def: "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN." [http://www.onelook.com/] subset: gosubset_prok xref: EC:3.5.5 xref: GO:0016815 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0003385 name: hydrolase activity, acting on acid anhydrides namespace: molecular_function def: "Catalysis of the hydrolysis of any acid anhydride." [GOC:jl] subset: gosubset_prok synonym: "hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement" NARROW [] xref: EC:3.6 xref: GO:0016817 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003386 name: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides namespace: molecular_function def: "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus." [GOC:jl] subset: gosubset_prok xref: EC:3.6.1 xref: GO:0016818 is_a: CCO:F0003385 ! hydrolase activity, acting on acid anhydrides [Term] id: CCO:F0003387 name: hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides namespace: molecular_function def: "Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-." [GOC:ai] synonym: "hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides" EXACT [] xref: EC:3.6.2 xref: GO:0016819 is_a: CCO:F0003385 ! hydrolase activity, acting on acid anhydrides [Term] id: CCO:F0003388 name: hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances namespace: molecular_function def: "Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane." [GOC:mah] subset: gosubset_prok xref: EC:3.6.3 xref: GO:0016820 is_a: CCO:F0003385 ! hydrolase activity, acting on acid anhydrides [Term] id: CCO:F0003389 name: hydrolase activity, acting on acid carbon-carbon bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any acid carbon-carbon bond." [GOC:jl] subset: gosubset_prok xref: EC:3.7 xref: GO:0016822 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003390 name: hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances namespace: molecular_function def: "Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group." [GOC:ai] subset: gosubset_prok xref: EC:3.7.1 xref: GO:0016823 is_a: CCO:F0003389 ! hydrolase activity, acting on acid carbon-carbon bonds [Term] id: CCO:F0003391 name: hydrolase activity, acting on acid halide bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any acid halide bond." [GOC:jl] subset: gosubset_prok xref: EC:3.8 xref: GO:0016824 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003392 name: hydrolase activity, acting on acid phosphorus-nitrogen bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond." [GOC:jl] xref: EC:3.9 xref: GO:0016825 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003393 name: hydrolase activity, acting on acid sulfur-nitrogen bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any acid sulfur-nitrogen bond." [GOC:jl] synonym: "hydrolase activity, acting on acid sulphur-nitrogen bonds" EXACT [] xref: EC:3.10 xref: GO:0016826 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003394 name: hydrolase activity, acting on acid carbon-phosphorus bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any acid carbon-phosphorus bond." [GOC:jl] subset: gosubset_prok xref: EC:3.11 xref: GO:0016827 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003395 name: hydrolase activity, acting on acid sulfur-sulfur bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any acid sulfur-sulfur bond." [GOC:jl] synonym: "hydrolase activity, acting on acid sulphur-sulphur bonds" EXACT [] xref: EC:3.12 xref: GO:0016828 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003396 name: lyase activity namespace: molecular_function def: "Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [EC:4.-.-.-, ISBN:0198547684] comment: Note that enzymes of class EC:4.99.-.- should also be annotated to this term. subset: goslim_candida subset: goslim_goa subset: goslim_pir subset: goslim_yeast subset: gosubset_prok synonym: "other lyase activity" NARROW [] xref: EC:4 xref: GO:0016829 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003397 name: carbon-carbon lyase activity namespace: molecular_function def: "Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:jl] comment: Note that enzymes of class EC:4.1.99.- should also be annotated to this term. subset: gosubset_prok synonym: "other carbon-carbon lyase activity" NARROW [] xref: EC:4.1 xref: GO:0016830 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0003398 name: carboxy-lyase activity namespace: molecular_function def: "Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound." [http://www.mercksource.com/] subset: gosubset_prok synonym: "decarboxylase activity" EXACT [] xref: EC:4.1.1 xref: GO:0016831 xref: Reactome:1605 is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0003399 name: aldehyde-lyase activity namespace: molecular_function def: "Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone." [http://www.mercksource.com/] subset: gosubset_prok synonym: "aldolase activity" BROAD [] xref: EC:4.1.2 xref: GO:0016228 xref: GO:0016832 is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0003400 name: oxo-acid-lyase activity namespace: molecular_function def: "Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid." [EC:4.1.3, GOC:jl] subset: gosubset_prok synonym: "oxo-acid lyase activity" EXACT [] synonym: "oxoacid lyase activity" EXACT [] xref: EC:4.1.3 xref: GO:0016833 is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0003401 name: carbon-oxygen lyase activity namespace: molecular_function def: "Catalysis of the breakage of a carbon-oxygen bond." [EC:4.2.-.-] comment: Note that enzymes of class EC:4.2.99.- should also be annotated to this term. subset: gosubset_prok synonym: "other carbon-oxygen lyase activity" NARROW [] xref: EC:4.2 xref: GO:0016835 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0003402 name: hydro-lyase activity namespace: molecular_function def: "Catalysis of the cleavage of a carbon-oxygen bond by elimination of water." [EC:4.2.1] subset: gosubset_prok xref: EC:4.2.1 xref: GO:0016836 is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0003403 name: carbon-oxygen lyase activity, acting on polysaccharides namespace: molecular_function def: "Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide." [EC:4.2.-.-] subset: gosubset_prok xref: EC:4.2.2 xref: GO:0016837 is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0003404 name: carbon-oxygen lyase activity, acting on phosphates namespace: molecular_function def: "Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate." [EC:4.2.-.-] subset: gosubset_prok xref: EC:4.2.3 xref: GO:0016838 is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0003405 name: carbon-nitrogen lyase activity namespace: molecular_function def: "Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99)." [EC:4.3.-.-] comment: Note that enzymes of class EC:4.3.99.- should also be annotated to this term. subset: gosubset_prok synonym: "other carbon-nitrogen lyase activity" NARROW [] xref: EC:4.3 xref: GO:0016840 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0003406 name: ammonia-lyase activity namespace: molecular_function def: "Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate." [EC:4.3.-.-, GOC:krc] subset: gosubset_prok xref: EC:4.3.1 xref: GO:0016841 is_a: CCO:F0003405 ! carbon-nitrogen lyase activity [Term] id: CCO:F0003407 name: amidine-lyase activity namespace: molecular_function def: "Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate." [EC:4.3.-.-, GOC:krc] subset: gosubset_prok xref: EC:4.3.2 xref: GO:0016842 is_a: CCO:F0003405 ! carbon-nitrogen lyase activity [Term] id: CCO:F0003408 name: amine-lyase activity namespace: molecular_function def: "Catalysis of the release of amides by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate." [EC:4.3.-.-, GOC:krc] subset: gosubset_prok xref: EC:4.3.3 xref: GO:0016843 is_a: CCO:F0003405 ! carbon-nitrogen lyase activity [Term] id: CCO:F0003409 name: strictosidine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3-alpha(S)-strictosidine = tryptamine + secologanin." [EC:4.3.3.2] subset: gosubset_prok synonym: "3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming)" EXACT [EC:4.3.3.2] synonym: "3-alpha(S)-strictosidine tryptamine-lyase activity" EXACT [EC:4.3.3.2] synonym: "STR activity" EXACT [EC:4.3.3.2] synonym: "strictosidine synthetase activity" EXACT [EC:4.3.3.2] xref: EC:4.3.3.2 xref: GO:0016844 xref: MetaCyc:STRICTOSIDINE-SYNTHASE-RXN is_a: CCO:F0003408 ! amine-lyase activity [Term] id: CCO:F0003410 name: carbon-sulfur lyase activity namespace: molecular_function def: "Catalysis of the elimination of H2S or substituted H2S." [EC:4.4.-.-] subset: gosubset_prok synonym: "carbon-sulphur lyase activity" EXACT [] xref: EC:4.4 xref: GO:0016846 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0003411 name: 1-aminocyclopropane-1-carboxylate synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine." [EC:4.4.1.14] subset: gosubset_prok synonym: "1-aminocyclopropane-1-carboxylate synthetase activity" EXACT [EC:4.4.1.14] synonym: "1-aminocyclopropane-1-carboxylic acid synthase activity" EXACT [EC:4.4.1.14] synonym: "1-aminocyclopropanecarboxylate synthase activity" EXACT [EC:4.4.1.14] synonym: "ACC synthase activity" EXACT [EC:4.4.1.14] synonym: "aminocyclopropanecarboxylate synthase activity" EXACT [EC:4.4.1.14] synonym: "aminocyclopropanecarboxylic acid synthase activity" EXACT [EC:4.4.1.14] synonym: "S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)" EXACT [EC:4.4.1.14] synonym: "S-adenosyl-L-methionine methylthioadenosine-lyase activity" EXACT [EC:4.4.1.14] xref: EC:4.4.1.14 xref: GO:0016847 xref: MetaCyc:4.4.1.14-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0003412 name: carbon-halide lyase activity namespace: molecular_function def: "Catalysis of the breakage of a bond between carbon and any halogen atom." [GOC:mah] subset: gosubset_prok xref: EC:4.5 xref: GO:0016848 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0003413 name: phosphorus-oxygen lyase activity namespace: molecular_function subset: gosubset_prok xref: EC:4.6 xref: GO:0016849 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0003414 name: magnesium chelatase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+." [EC:6.6.1.1] comment: Note that this was EC:4.99.1.1. subset: gosubset_prok synonym: "magnesium-chelatase activity" EXACT [EC:6.6.1.1] synonym: "magnesium-protoporphyrin chelatase activity" EXACT [EC:6.6.1.1] synonym: "magnesium-protoporphyrin IX chelatase activity" EXACT [EC:6.6.1.1] synonym: "Mg-chelatase activity" BROAD [EC:6.6.1.1] synonym: "Mg-protoporphyrin IX chelatase activity" EXACT [EC:6.6.1.1] synonym: "Mg-protoporphyrin IX magnesio-lyase activity" EXACT [EC:6.6.1.1] synonym: "Mg-protoporphyrin IX magnesium-lyase activity" EXACT [EC:6.6.1.1] synonym: "protoporphyrin IX magnesium-chelatase activity" EXACT [EC:6.6.1.1] synonym: "protoporphyrin IX Mg-chelatase activity" EXACT [EC:6.6.1.1] xref: EC:6.6.1.1 xref: GO:0016851 is_a: CCO:F0008029 ! ligase activity, forming nitrogen-metal bonds, forming coordination complexes [Term] id: CCO:F0003415 name: sirohydrochlorin cobaltochelatase activity namespace: molecular_function def: "Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+." [EC:4.99.1.3] subset: gosubset_prok synonym: "anaerobic cobalt chelatase activity" EXACT [] synonym: "CbiK" NARROW [] synonym: "CbiX" RELATED [EC:4.99.1.3] synonym: "CbiXS" RELATED [EC:4.99.1.3] synonym: "cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming)" EXACT [EC:4.99.1.3] synonym: "sirohydrochlorin cobalt-lyase activity" EXACT [EC:4.99.1.3] xref: EC:4.99.1.3 xref: GO:0016852 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0003416 name: isomerase activity namespace: molecular_function def: "Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that enzymes of class EC:5.99.-.- should also be annotated to this term. subset: goslim_candida subset: goslim_goa subset: goslim_pir subset: goslim_yeast subset: gosubset_prok synonym: "other isomerase activity" NARROW [] xref: EC:5 xref: GO:0016853 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003417 name: racemase and epimerase activity namespace: molecular_function def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that enzymes of class EC:5.1.99.- should also be annotated to this term. Note that 'epimerase' refers to the conversion of an epimer into its diastereoisomer, and 'racemase' refers to the interconversion of the two enantiomers of a chiral compound. subset: gosubset_prok synonym: "racemase and epimerase activity, acting on other compounds" NARROW [] xref: EC:5.1 xref: GO:0016854 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0003418 name: racemase and epimerase activity, acting on amino acids and derivatives namespace: molecular_function def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid." [GOC:mah] subset: gosubset_prok xref: EC:5.1.1 xref: GO:0016855 is_a: CCO:F0003417 ! racemase and epimerase activity [Term] id: CCO:F0003419 name: racemase and epimerase activity, acting on hydroxy acids and derivatives namespace: molecular_function def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule." [GOC:mah] subset: gosubset_prok xref: EC:5.1.2 xref: GO:0016856 is_a: CCO:F0003417 ! racemase and epimerase activity [Term] id: CCO:F0003420 name: racemase and epimerase activity, acting on carbohydrates and derivatives namespace: molecular_function def: "Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule." [GOC:mah] subset: gosubset_prok xref: EC:5.1.3 xref: GO:0016857 is_a: CCO:F0003417 ! racemase and epimerase activity [Term] id: CCO:F0003421 name: cis-trans isomerase activity namespace: molecular_function def: "Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:5.2 xref: GO:0016859 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0003422 name: intramolecular oxidoreductase activity namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears." [EC:5.3.-.-] comment: Note that enzymes of class EC:5.3.99.- should also be annotated to this term. subset: gosubset_prok synonym: "intramolecular isomerase activity" EXACT [] synonym: "intramolecular oxidoreductase activity, other intramolecular oxidoreductases" NARROW [] xref: EC:5.3 xref: GO:0016860 xref: Reactome:1429 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0003423 name: intramolecular oxidoreductase activity, interconverting aldoses and ketoses namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears." [GOC:jl] subset: gosubset_prok synonym: "intramolecular isomerase activity, interconverting aldoses and ketoses" EXACT [] xref: EC:5.3.1 xref: GO:0016861 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0003424 name: intramolecular oxidoreductase activity, interconverting keto- and enol-groups namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears." [GOC:jl] subset: gosubset_prok synonym: "intramolecular isomerase activity, interconverting keto- and enol-groups" EXACT [] xref: EC:5.3.2 xref: GO:0016862 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0003425 name: intramolecular oxidoreductase activity, transposing C=C bonds namespace: molecular_function subset: gosubset_prok synonym: "intramolecular isomerase activity, transposing C=C bonds" EXACT [] xref: EC:5.3.3 xref: GO:0016863 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0003426 name: intramolecular oxidoreductase activity, transposing S-S bonds namespace: molecular_function subset: gosubset_prok synonym: "intramolecular isomerase activity, transposing S-S bonds" EXACT [] xref: EC:5.3.4 xref: GO:0016864 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0003427 name: intramolecular transferase activity namespace: molecular_function def: "Catalysis of the transfer of a functional group from one position to another within a single molecule." [GOC:mah] comment: Note that enzymes of class EC:5.4.99.- should also be annotated to this term. subset: gosubset_prok synonym: "intramolecular transferase activity, transferring other groups" NARROW [] synonym: "mutase activity" EXACT [] xref: EC:5.4 xref: GO:0016866 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0003428 name: intramolecular transferase activity, transferring acyl groups namespace: molecular_function def: "Catalysis of the transfer of an acyl group from one position to another within a single molecule." [GOC:mah] subset: gosubset_prok xref: EC:5.4.1 xref: GO:0016867 is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0003429 name: intramolecular transferase activity, phosphotransferases namespace: molecular_function def: "Catalysis of the transfer of a phosphate group from one position to another within a single molecule." [GOC:mah] subset: gosubset_prok synonym: "phosphomutase activity" EXACT [] xref: EC:5.4.2 xref: GO:0016868 is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0003430 name: intramolecular transferase activity, transferring amino groups namespace: molecular_function def: "Catalysis of the transfer of an amino group from one position to another within a single molecule." [GOC:mah] subset: gosubset_prok xref: EC:5.4.3 xref: GO:0016869 is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0003431 name: cycloartenol synthase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol." [EC:5.4.99.8] subset: gosubset_prok synonym: "(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)" EXACT [EC:5.4.99.8] synonym: "2,3-epoxysqualene cycloartenol-cyclase activity" EXACT [EC:5.4.99.8] synonym: "2,3-epoxysqualene--cycloartenol cyclase activity" EXACT [EC:5.4.99.8] synonym: "2,3-oxidosqualene-cycloartenol cyclase activity" EXACT [EC:5.4.99.8] synonym: "oxidosqualene:cycloartenol cyclase activity" EXACT [PMID:18033581] synonym: "squalene-2,3-epoxide-cycloartenol cyclase activity" EXACT [EC:5.4.99.8] xref: EC:5.4.99.8 xref: GO:0016871 xref: MetaCyc:CYCLOARTENOL-SYNTHASE-RXN is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0003432 name: intramolecular lyase activity namespace: molecular_function def: "The catalysis of certain rearrangements of a molecule to break or form a ring." [GOC:jl, http://www.mercksource.com/] subset: gosubset_prok xref: EC:5.5 xref: GO:0016872 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0003433 name: ligase activity namespace: molecular_function def: "Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_goa subset: goslim_pir subset: goslim_yeast subset: gosubset_prok xref: EC:6 xref: GO:0016874 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003434 name: ligase activity, forming carbon-oxygen bonds namespace: molecular_function def: "Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok xref: EC:6.1 xref: GO:0016875 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0003435 name: ligase activity, forming aminoacyl-tRNA and related compounds namespace: molecular_function def: "Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound." [GOC:jl] subset: gosubset_prok xref: EC:6.1.1 xref: GO:0016876 is_a: CCO:F0003434 ! ligase activity, forming carbon-oxygen bonds [Term] id: CCO:F0003436 name: ligase activity, forming carbon-sulfur bonds namespace: molecular_function def: "Catalysis of the ligation of two substances via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok synonym: "ligase activity, forming carbon-sulphur bonds" EXACT [] xref: EC:6.2 xref: GO:0016877 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0003437 name: acid-thiol ligase activity namespace: molecular_function def: "Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok xref: EC:6.2.1 xref: GO:0016878 is_a: CCO:F0003436 ! ligase activity, forming carbon-sulfur bonds [Term] id: CCO:F0003438 name: ligase activity, forming carbon-nitrogen bonds namespace: molecular_function def: "Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] comment: Note that enzymes of class EC:6.3.4.- should also be annotated to this term. subset: gosubset_prok synonym: "other carbon-nitrogen ligase activity" NARROW [] xref: EC:6.3 xref: GO:0016879 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0003439 name: acid-ammonia (or amide) ligase activity namespace: molecular_function def: "Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok synonym: "amide synthase activity" EXACT [] xref: EC:6.3.1 xref: GO:0016880 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003440 name: acid-amino acid ligase activity namespace: molecular_function def: "Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok synonym: "peptide synthase activity" EXACT [] xref: EC:6.3.2 xref: GO:0016881 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003441 name: cyclo-ligase activity namespace: molecular_function def: "Catalysis of the ligation of two substances via a carbon-nitrogen bond to form a heterocyclic product, with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [EC:6.3.3.1, EC:6.3.3.2, EC:6.3.3.4, GOC:mah] subset: gosubset_prok xref: EC:6.3.3 xref: GO:0016882 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003442 name: carbon-nitrogen ligase activity, with glutamine as amido-N-donor namespace: molecular_function def: "Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction." [PMID:12360532] subset: gosubset_prok xref: EC:6.3.5 xref: GO:0016003 xref: GO:0016884 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003443 name: ligase activity, forming carbon-carbon bonds namespace: molecular_function def: "Catalysis of the ligation of two substances via a carbon-carbon bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok xref: EC:6.4 xref: GO:0016885 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0003444 name: ligase activity, forming phosphoric ester bonds namespace: molecular_function def: "Catalysis of the ligation of two substances via a phosphoric ester bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:jl] subset: gosubset_prok xref: EC:6.5 xref: GO:0016886 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0003445 name: ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "(Ca2+ + Mg2+)-ATPase" NARROW [EC:3.6.1.3] synonym: "adenosine 5'-triphosphatase activity" EXACT [EC:3.6.1.3] synonym: "adenosine triphosphatase activity" EXACT [EC:3.6.1.3] synonym: "adenosinetriphosphatase activity" EXACT [] synonym: "ATP hydrolase activity" EXACT [EC:3.6.1.3] synonym: "ATP monophosphatase activity" EXACT [EC:3.6.1.3] synonym: "ATP phosphohydrolase activity" EXACT [] synonym: "complex V (mitochondrial electron transport)" RELATED [EC:3.6.1.3] synonym: "HCO3--ATPase" NARROW [EC:3.6.1.3] synonym: "SV40 T-antigen" RELATED [EC:3.6.1.3] xref: GO:0004002 xref: GO:0016887 is_a: CCO:F0003574 ! nucleoside-triphosphatase activity [Term] id: CCO:F0003446 name: endodeoxyribonuclease activity, producing 5'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters." [GOC:ai] subset: gosubset_prok synonym: "endodeoxyribonuclease activity, producing 5' phosphomonoesters" EXACT [] xref: EC:3.1.21 xref: GO:0016888 is_a: CCO:F0000917 ! endodeoxyribonuclease activity is_a: CCO:F0003451 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [Term] id: CCO:F0003447 name: endodeoxyribonuclease activity, producing 3'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters." [GOC:ai] subset: gosubset_prok synonym: "endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters" EXACT [] xref: EC:3.1.22 xref: GO:0016889 is_a: CCO:F0000917 ! endodeoxyribonuclease activity is_a: CCO:F0003452 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [Term] id: CCO:F0003448 name: site-specific endodeoxyribonuclease activity, specific for altered base namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks." [GOC:jl] subset: gosubset_prok xref: EC:3.1.25 xref: GO:0016890 is_a: CCO:F0000917 ! endodeoxyribonuclease activity [Term] id: CCO:F0003449 name: endoribonuclease activity, producing 5'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters." [GOC:ai] subset: gosubset_prok xref: EC:3.1.26 xref: GO:0016891 is_a: CCO:F0000918 ! endoribonuclease activity is_a: CCO:F0003451 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [Term] id: CCO:F0003450 name: endoribonuclease activity, producing 3'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters." [GOC:ai] subset: gosubset_prok synonym: "endoribonuclease activity, producing other than 5'-phosphomonoesters" EXACT [] xref: EC:3.1.27 xref: GO:0016892 is_a: CCO:F0000918 ! endoribonuclease activity is_a: CCO:F0003452 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [Term] id: CCO:F0003451 name: endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters." [GOC:mah] comment: Note that this activity can catalyze cleavage of DNA or RNA. subset: gosubset_prok synonym: "5'-endonuclease activity" EXACT [] synonym: "endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters" RELATED [] xref: EC:3.1.30 xref: GO:0016893 is_a: CCO:F0000916 ! endonuclease activity [Term] id: CCO:F0003452 name: endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters." [GOC:mah] comment: Note that this activity can catalyze cleavage of DNA or RNA. subset: gosubset_prok synonym: "3'-endonuclease activity" EXACT [] synonym: "endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters" RELATED [] xref: EC:3.1.31 xref: GO:0016894 is_a: CCO:F0000916 ! endonuclease activity [Term] id: CCO:F0003453 name: exodeoxyribonuclease activity, producing 5'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters." [GOC:ai] subset: gosubset_prok synonym: "exodeoxyribonuclease activity, producing 5' phosphomonoesters" EXACT [] xref: EC:3.1.11 xref: GO:0016895 is_a: CCO:F0000925 ! exodeoxyribonuclease activity is_a: CCO:F0003366 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [Term] id: CCO:F0003454 name: exoribonuclease activity, producing 5'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters." [GOC:ai] subset: gosubset_prok synonym: "exoribonuclease activity, producing 5' phosphomonoesters" EXACT [] xref: EC:3.1.13 xref: GO:0016896 is_a: CCO:F0000928 ! exoribonuclease activity is_a: CCO:F0003366 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [Term] id: CCO:F0003455 name: exoribonuclease activity, producing 3'-phosphomonoesters namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters." [GOC:ai] xref: EC:3.1.14 xref: GO:0016897 is_a: CCO:F0000928 ! exoribonuclease activity is_a: CCO:F0003367 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [Term] id: CCO:F0003456 name: oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule." [GOC:ai] subset: gosubset_prok xref: EC:1.1.2 xref: GO:0016898 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003457 name: oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule." [GOC:ai] subset: gosubset_prok xref: EC:1.1.3 xref: GO:0016899 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003458 name: oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule." [GOC:ai] synonym: "oxidoreductase activity, acting on the CH-OH group of donors, disulphide as acceptor" EXACT [] xref: EC:1.1.4 xref: GO:0016900 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003459 name: oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule." [GOC:ai] subset: gosubset_prok xref: EC:1.1.5 xref: GO:0016901 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003460 name: oxidoreductase activity, acting on the aldehyde or oxo group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:ai] comment: Note that enzymes of class EC:1.2.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors" NARROW [] xref: EC:1.2 xref: GO:0016903 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003461 name: myosin heavy chain kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate." [EC:2.7.11.7] synonym: "ATP:myosin heavy-chain O-phosphotransferase activity" EXACT [EC:2.7.11.7] synonym: "ATP:myosin-heavy-chain O-phosphotransferase activity" EXACT [EC:2.7.11.7] synonym: "calmodulin-dependent myosin heavy chain kinase activity" EXACT [EC:2.7.11.7] synonym: "MHCK" RELATED [EC:2.7.11.7] synonym: "MIHC kinase activity" EXACT [EC:2.7.11.7] synonym: "myosin heavy chain kinase A activity" EXACT [EC:2.7.11.7] synonym: "myosin heavy-chain kinase activity" EXACT [EC:2.7.11.7] synonym: "myosin I heavy-chain kinase activity" NARROW [EC:2.7.11.7] synonym: "myosin II heavy-chain kinase activity" NARROW [EC:2.7.11.7] synonym: "myosin-heavy-chain kinase activity" EXACT [EC:2.7.11.7] synonym: "STK6" RELATED [EC:2.7.11.7] xref: EC:2.7.11.7 xref: GO:0016905 xref: MetaCyc:MYOSIN-HEAVY-CHAIN-KINASE-RXN is_a: CCO:F0001053 ! calmodulin-dependent protein kinase activity [Term] id: CCO:F0003462 name: sterol 3-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol." [EC:2.4.1.173] synonym: "sterol 3beta-glucosyltransferase activity" EXACT [EC:2.4.1.173] synonym: "sterol glucosyltransferase activity" EXACT [] synonym: "sterol-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.173] synonym: "sterol:UDPG glucosyltransferase activity" EXACT [] synonym: "UDP-glucose-sterol beta-glucosyltransferase activity" EXACT [EC:2.4.1.173] synonym: "UDP-glucose-sterol glucosyltransferase activity" EXACT [EC:2.4.1.173] synonym: "UDP-glucose:sterol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.173] synonym: "UDP-glucose:sterol glucosyltransferase activity" EXACT [] synonym: "UDPG-SGTase activity" EXACT [EC:2.4.1.173] synonym: "UDPG:sterol glucosyltransferase activity" EXACT [] synonym: "UDPglucose:sterol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.173] synonym: "uridine diphosphoglucose-poriferasterol glucosyltransferase activity" EXACT [EC:2.4.1.173] synonym: "uridine diphosphoglucose-sterol glucosyltransferase activity" EXACT [EC:2.4.1.173] xref: EC:2.4.1.173 xref: GO:0016906 xref: MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0003463 name: G-protein coupled acetylcholine receptor activity namespace: molecular_function synonym: "G protein coupled acetylcholine receptor activity" EXACT [] synonym: "G-protein-coupled acetylcholine receptor activity" EXACT [] xref: GO:0016907 is_a: CCO:F0001782 ! amine receptor activity is_a: CCO:F0002870 ! acetylcholine receptor activity [Term] id: CCO:F0003464 name: MAP kinase 2 activity namespace: molecular_function synonym: "ERK2" EXACT [] xref: EC:2.7.11.- xref: GO:0016908 is_a: CCO:F0001073 ! MAP kinase activity [Term] id: CCO:F0003465 name: SAP kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines." [GOC:ma] synonym: "SAPK" EXACT [] synonym: "stress-activated kinase activity" EXACT [] synonym: "stress-activated protein kinase activity" EXACT [] xref: EC:2.7.11.- xref: GO:0016909 is_a: CCO:F0001073 ! MAP kinase activity [Term] id: CCO:F0003466 name: follicle-stimulating hormone activity namespace: molecular_function def: "A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland." [ISBN:0198547684] xref: GO:0016913 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0003467 name: GABA receptor activity namespace: molecular_function def: "Combining with gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to initiate a change in cell activity." [GOC:jl, http://cancerweb.ncl.ac.uk/] comment: See also the molecular function term 'neurotransmitter receptor activity ; GO:0030594'. synonym: "4-aminobutanoate receptor activity" EXACT [] synonym: "4-aminobutyrate receptor activity" EXACT [] synonym: "GABA binding" EXACT [] synonym: "gamma-aminobutyrate binding" EXACT [] synonym: "gamma-aminobutyric acid binding" EXACT [] synonym: "gamma-aminobutyric acid receptor activity" EXACT [] xref: GO:0016917 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0003468 name: retinal binding namespace: molecular_function def: "Interacting selectively with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina." [http://cancerweb.ncl.ac.uk/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "blue-sensitive opsin" RELATED [] synonym: "green-sensitive opsin" RELATED [] synonym: "long-wave-sensitive opsin" RELATED [] synonym: "opsin" RELATED [] synonym: "red-sensitive opsin" RELATED [] synonym: "retinaldehyde binding" EXACT [] synonym: "short-wave-sensitive opsin" RELATED [] synonym: "UV-sensitive opsin" RELATED [] synonym: "violet-sensitive opsin" RELATED [] synonym: "vitamin A binding" BROAD [] xref: GO:0016918 is_a: CCO:F0001639 ! retinoid binding is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0003469 name: nardilysin activity namespace: molecular_function def: "Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys." [EC:3.4.24.61] synonym: "N-arginine dibasic convertase activity" EXACT [EC:3.4.24.61] synonym: "NRD convertase activity" EXACT [EC:3.4.24.61] synonym: "NRD-convertase activity" EXACT [EC:3.4.24.61] xref: EC:3.4.24.61 xref: GO:0016919 xref: MetaCyc:3.4.24.61-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0003470 name: pyroglutamyl-peptidase activity namespace: molecular_function subset: gosubset_prok xref: EC:3.4.19.- xref: GO:0016920 is_a: CCO:F0001792 ! omega peptidase activity [Term] id: CCO:F0003471 name: pyroglutamyl-peptidase II activity namespace: molecular_function def: "Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides." [EC:3.4.19.6] synonym: "PAP-II activity" EXACT [EC:3.4.19.6] synonym: "pyroglutamate aminopeptidase II" RELATED [EC:3.4.19.6] synonym: "pyroglutamyl aminopeptidase II activity" EXACT [EC:3.4.19.6] synonym: "pyroglutamyl peptidase II" RELATED [EC:3.4.19.6] synonym: "thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.6] synonym: "thyroliberinase activity" NARROW [EC:3.4.19.6] synonym: "thyrotropin-releasing factor pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.6] synonym: "thyrotropin-releasing hormone degrading ectoenzyme activity" NARROW [EC:3.4.19.6] synonym: "thyrotropin-releasing hormone-degrading peptidase activity" EXACT [EC:3.4.19.6] synonym: "thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity" EXACT [EC:3.4.19.6] synonym: "TRH-DE activity" NARROW [EC:3.4.19.6] synonym: "TRH-degrading ectoenzyme activity" NARROW [EC:3.4.19.6] synonym: "TRH-specific aminopeptidase activity" NARROW [EC:3.4.19.6] xref: EC:3.4.19.6 xref: GO:0016921 xref: MetaCyc:3.4.19.6-RXN is_a: CCO:F0001787 ! metallopeptidase activity is_a: CCO:F0003470 ! pyroglutamyl-peptidase activity [Term] id: CCO:F0003472 name: ligand-dependent nuclear receptor binding namespace: molecular_function def: "Interacting selectively, in a ligand dependent manner, with a nuclear receptor protein." [GOC:mah, PMID:7776974] synonym: "ligand-dependent nuclear receptor interactor activity" RELATED [] xref: GO:0016922 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0003473 name: SUMO-specific protease activity namespace: molecular_function def: "Catalysis of the hydrolysis of SUMO, a small ubiquitin-related modifier, from previously sumoylated substrates." [GOC:rn, PMID:10094048, PMID:11031248, PMID:11265250] synonym: "SUSP" NARROW [] synonym: "ULP" NARROW [] xref: GO:0016929 is_a: CCO:F0004166 ! small conjugating protein-specific protease activity [Term] id: CCO:F0003474 name: vasopressin activated calcium mobilizing receptor activity namespace: molecular_function xref: GO:0016931 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0003475 name: extracellular-glycine-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] synonym: "glycine receptor" BROAD [] xref: GO:0016933 is_a: CCO:F0001506 ! excitatory extracellular ligand-gated ion channel activity [Term] id: CCO:F0003476 name: extracellular-glycine-gated chloride channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] synonym: "glycine receptor" BROAD [] xref: GO:0016934 is_a: CCO:F0001522 ! chloride channel activity is_a: CCO:F0003475 ! extracellular-glycine-gated ion channel activity [Term] id: CCO:F0003477 name: galactoside binding namespace: molecular_function def: "Interacting selectively with any glycoside in which the sugar moiety is galactose." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0016936 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0003478 name: short-branched-chain-acyl-CoA dehydrogenase activity namespace: molecular_function xref: EC:1.3.99.- xref: GO:0016937 is_a: CCO:F0000480 ! acyl-CoA dehydrogenase activity [Term] id: CCO:F0003479 name: natriuretic peptide receptor activity namespace: molecular_function xref: GO:0016941 is_a: CCO:F0000195 ! peptide receptor activity [Term] id: CCO:F0003480 name: RNA polymerase I transcription elongation factor activity namespace: molecular_function def: "Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation." [GOC:mah] synonym: "Pol I transcription elongation factor activity" EXACT [] xref: GO:0016943 is_a: CCO:F0000298 ! transcription elongation regulator activity [Term] id: CCO:F0003481 name: RNA polymerase II transcription elongation factor activity namespace: molecular_function def: "Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation." [GOC:mah] synonym: "Pol II transcription elongation factor activity" EXACT [] xref: GO:0016944 is_a: CCO:F0000298 ! transcription elongation regulator activity [Term] id: CCO:F0003482 name: RNA polymerase III transcription elongation factor activity namespace: molecular_function def: "Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation." [GOC:mah] synonym: "Pol III transcription elongation factor activity" EXACT [] xref: GO:0016945 is_a: CCO:F0000298 ! transcription elongation regulator activity [Term] id: CCO:F0003483 name: cathepsin F activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2." [EC:3.4.22.41] xref: EC:3.4.22.41 xref: GO:0016946 xref: MetaCyc:3.4.22.41-RXN is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0003484 name: class I ribonucleotide reductase activity namespace: molecular_function synonym: "aerobic non-heme iron-dependent ribonucleotide reductase activity" EXACT [] xref: GO:0016959 xref: Reactome:4419 is_a: CCO:F0001113 ! ribonucleoside-diphosphate reductase activity [Term] id: CCO:F0003485 name: class II ribonucleotide reductase activity namespace: molecular_function synonym: "adenosylcobalamin-dependent ribonucleotide reductase activity" EXACT [] synonym: "class II ribonucleoside-diphosphate reductase activity" EXACT [] xref: GO:0016960 is_a: CCO:F0001113 ! ribonucleoside-diphosphate reductase activity [Term] id: CCO:F0003486 name: class III ribonucleotide reductase activity namespace: molecular_function synonym: "anaerobic iron-sulfur-dependent ribonucleotide reductase activity" EXACT [] xref: GO:0016961 is_a: CCO:F0001113 ! ribonucleoside-diphosphate reductase activity [Term] id: CCO:F0003487 name: alpha-2 macroglobulin receptor activity namespace: molecular_function def: "Combining with an alpha-2 macroglobulin to initiate a change in cell activity." [GOC:ma] xref: GO:0016964 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0003488 name: nitric oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: nitrous oxide + acceptor + H2O = 2 nitric oxide + reduced acceptor." [EC:1.7.99.7, MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN] subset: gosubset_prok synonym: "CYP55" NARROW [] synonym: "cytochrome bc nitric oxide reductase activity" NARROW [] synonym: "nitric-oxide reductase activity" EXACT [EC:1.7.99.7] synonym: "nitrogen oxide reductase activity" EXACT [EC:1.7.99.7] synonym: "nitrous-oxide:(acceptor) oxidoreductase (NO-forming)" EXACT [EC:1.7.99.7] synonym: "nitrous-oxide:acceptor oxidoreductase (NO-forming)" EXACT [EC:1.7.99.7] synonym: "P450 nitric oxide reductase activity" NARROW [] synonym: "P450nor" NARROW [] xref: EC:1.7.99.7 xref: GO:0016966 xref: GO:0016967 xref: GO:0016968 xref: MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0003489 name: flavin-linked sulfhydryl oxidase activity namespace: molecular_function def: "Catalysis of the formation of disulfide bridges." [PMID:10899311] xref: GO:0016971 is_a: CCO:F0003490 ! thiol oxidase activity [Term] id: CCO:F0003490 name: thiol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O." [EC:1.8.3.2] synonym: "sulfhydryl oxidase activity" EXACT [EC:1.8.3.2] synonym: "thiol:oxygen oxidoreductase activity" EXACT [EC:1.8.3.2] xref: EC:1.8.3.2 xref: GO:0016972 xref: MetaCyc:THIOL-OXIDASE-RXN xref: UM-BBD_enzymeID:e0808 is_a: CCO:F0003263 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor [Term] id: CCO:F0003491 name: sodium channel auxiliary protein activity namespace: molecular_function xref: GO:0016974 is_a: CCO:F0002865 ! auxiliary transport protein activity [Term] id: CCO:F0003493 name: chitosanase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan." [EC:3.2.1.132] subset: gosubset_prok synonym: "chitosan N-acetylglucosaminohydrolase activity" EXACT [EC:3.2.1.132] xref: EC:3.2.1.132 xref: GO:0016977 xref: MetaCyc:3.2.1.132-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003494 name: lipoate-protein ligase activity namespace: molecular_function def: "Catalysis of the formation of carbon-nitrogen bonds between lipoate (5-(1,2-dithiolan-3-yl)pentanoate) and a protein." [EC:6.3.4.-] subset: gosubset_prok synonym: "lipoate-protein ligase A activity" NARROW [] synonym: "lipoate-protein ligase B activity" NARROW [] xref: EC:6.3.4.- xref: GO:0008916 xref: GO:0016978 xref: GO:0016979 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003495 name: creatinase activity namespace: molecular_function def: "Catalysis of the reaction: creatine + H2O = sarcosine + urea." [EC:3.5.3.3] subset: gosubset_prok synonym: "creatine amidinohydrolase activity" EXACT [EC:3.5.3.3] xref: EC:3.5.3.3 xref: GO:0016980 xref: MetaCyc:CREATINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003496 name: cytokine beta-glucosidase activity namespace: molecular_function xref: GO:0016983 is_a: CCO:F0001889 ! beta-glucosidase activity [Term] id: CCO:F0003497 name: ribulose-bisphosphate carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate." [EC:4.1.1.39] subset: gosubset_prok synonym: "3-phospho-D-glycerate carboxy-lyase (dimerizing)" EXACT [EC:4.1.1.39] synonym: "3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming)" EXACT [EC:4.1.1.39] synonym: "carboxydismutase activity" RELATED [EC:4.1.1.39] synonym: "D-ribulose 1,5-diphosphate carboxylase activity" EXACT [EC:4.1.1.39] synonym: "D-ribulose-1,5-bisphosphate carboxylase activity" EXACT [EC:4.1.1.39] synonym: "diphosphoribulose carboxylase activity" EXACT [EC:4.1.1.39] synonym: "ribulose 1,5-bisphosphate carboxylase activity" EXACT [EC:4.1.1.39] synonym: "ribulose 1,5-bisphosphate carboxylase/oxygenase activity" EXACT [] synonym: "ribulose 1,5-diphosphate carboxylase activity" EXACT [EC:4.1.1.39] synonym: "ribulose 1,5-diphosphate carboxylase/oxygenase activity" EXACT [EC:4.1.1.39] synonym: "ribulose bisphosphate carboxylase/oxygenase activity" EXACT [EC:4.1.1.39] synonym: "ribulose diphosphate carboxylase activity" EXACT [EC:4.1.1.39] synonym: "ribulose diphosphate carboxylase/oxygenase activity" EXACT [EC:4.1.1.39] synonym: "rubisco activity" EXACT [] synonym: "RuBisCO activity" EXACT [EC:4.1.1.39] synonym: "RuBP carboxylase activity" EXACT [EC:4.1.1.39] xref: EC:4.1.1.39 xref: GO:0016984 xref: MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003498 name: mannan endo-1,4-beta-mannosidase activity namespace: molecular_function def: "Catalysis of the random hydrolysis of 1,4-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans." [EC:3.2.1.78] subset: gosubset_prok synonym: "1,4-beta-D-mannan mannanohydrolase activity" EXACT [EC:3.2.1.78] synonym: "beta-1, 4-mannan 4-mannanohydrolase activity" EXACT [EC:3.2.1.78] synonym: "beta-D-mannanase activity" EXACT [EC:3.2.1.78] synonym: "beta-mannanase activity" EXACT [EC:3.2.1.78] synonym: "beta-mannanase B" RELATED [EC:3.2.1.78] synonym: "endo-1,4-beta-mannanase activity" EXACT [EC:3.2.1.78] synonym: "endo-1,4-mannanase activity" EXACT [EC:3.2.1.78] synonym: "endo-beta-1,4-mannase activity" EXACT [EC:3.2.1.78] synonym: "endo-beta-mannanase activity" EXACT [EC:3.2.1.78] xref: EC:3.2.1.78 xref: GO:0016985 xref: MetaCyc:3.2.1.78-RXN is_a: CCO:F0000951 ! beta-mannosidase activity [Term] id: CCO:F0003499 name: transcription initiation factor activity namespace: molecular_function subset: gosubset_prok synonym: "transcriptional initiation factor activity" EXACT [] xref: GO:0016986 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0003500 name: sigma factor activity namespace: molecular_function def: "A sigma factor is the promoter specificity subunit of eubacterial-type multisubunit RNA polymerases, those whose core subunit composition is often described as alpha(2)-beta-beta-prime. (This type of multisubunit RNA polymerase complex is known to be found in eubacteria and plant plastids). Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, this binds specifically to promoter sequences, with the sigma factor making sequence specific contacts with the promoter elements. The sigma subunit is released from the elongating form of the polymerase and is thus free to act catalytically for multiple RNA polymerase core enzymes." [GOC:krc] subset: gosubset_prok synonym: "sigma transcription factor" RELATED [] xref: GO:0016987 is_a: CCO:F0003499 ! transcription initiation factor activity [Term] id: CCO:F0003501 name: transcription initiation factor antagonist activity namespace: molecular_function def: "The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity." [GOC:jl] subset: gosubset_prok synonym: "transcriptional initiation factor antagonist activity" EXACT [] xref: GO:0016988 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0003502 name: sigma factor antagonist activity namespace: molecular_function def: "The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity." [GOC:jl, http://en.wikipedia.org/wiki/Anti-sigma_factors] subset: gosubset_prok synonym: "anti-sigma factor activity" EXACT [] xref: GO:0016989 is_a: CCO:F0003501 ! transcription initiation factor antagonist activity [Term] id: CCO:F0003503 name: arginine deiminase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3." [EC:3.5.3.6] subset: gosubset_prok synonym: "arginine dihydrolase activity" EXACT [EC:3.5.3.6] synonym: "citrulline iminase activity" EXACT [EC:3.5.3.6] synonym: "L-arginine deiminase activity" EXACT [EC:3.5.3.6] synonym: "L-arginine iminohydrolase activity" EXACT [EC:3.5.3.6] xref: EC:3.5.3.6 xref: GO:0016990 xref: MetaCyc:ARGININE-DEIMINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003504 name: lipoate synthase activity namespace: molecular_function def: "Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl." [EC:2.8.1.8] subset: gosubset_prok synonym: "LipA" RELATED [EC:2.8.1.8] synonym: "lipoyl synthase activity" EXACT [EC:2.8.1.8] synonym: "LS" RELATED [EC:2.8.1.8] synonym: "protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity" EXACT [EC:2.8.1.8] synonym: "protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity" EXACT [EC:2.8.1.8] xref: EC:2.8.1.8 xref: GO:0016992 is_a: CCO:F0003355 ! sulfurtransferase activity is_a: CCO:F0003494 ! lipoate-protein ligase activity [Term] id: CCO:F0003505 name: precorrin-8X methylmutase activity namespace: molecular_function def: "Catalysis of the reaction: precorrin-8X = hydrogenobyrinate." [EC:5.4.1.2] subset: gosubset_prok synonym: "HBA synthase activity" EXACT [EC:5.4.1.2] synonym: "hydrogenobyrinic acid-binding protein activity" NARROW [EC:5.4.1.2] synonym: "precorrin isomerase activity" EXACT [EC:5.4.1.2] synonym: "precorrin-8X 11,12-methylmutase activity" EXACT [EC:5.4.1.2] xref: EC:5.4.1.2 xref: GO:0016993 xref: MetaCyc:5.4.1.2-RXN is_a: CCO:F0003428 ! intramolecular transferase activity, transferring acyl groups [Term] id: CCO:F0003506 name: precorrin-6A reductase activity namespace: molecular_function def: "Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+." [EC:1.3.1.54] subset: gosubset_prok synonym: "precorrin-6B:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.54] synonym: "precorrin-6X reductase activity" EXACT [] synonym: "precorrin-6Y:NADP(+) oxidoreductase activity" EXACT [EC:1.3.1.54] synonym: "precorrin-6Y:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.54] xref: EC:1.3.1.54 xref: GO:0016994 xref: MetaCyc:1.3.1.54-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003507 name: cholesterol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: cholesterol + O2 = cholest-4-en-3-one + H2O2." [EC:1.1.3.6] synonym: "3beta-hydroxy steroid oxidoreductase activity" EXACT [EC:1.1.3.6] synonym: "3beta-hydroxysteroid:oxygen oxidoreductase activity" EXACT [EC:1.1.3.6] synonym: "cholesterol- O2 oxidoreductase activity" EXACT [EC:1.1.3.6] synonym: "cholesterol-O(2) oxidoreductase activity" EXACT [EC:1.1.3.6] synonym: "cholesterol-O2 oxidoreductase activity" EXACT [EC:1.1.3.6] synonym: "cholesterol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.6] xref: EC:1.1.3.6 xref: GO:0016995 xref: MetaCyc:CHOLESTEROL-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0003508 name: endo-alpha-sialidase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids." [EC:3.2.1.129] synonym: "alpha-2,8-sialosylhydrolase activity" EXACT [EC:3.2.1.129] synonym: "endo-N-acetylneuraminidase activity" EXACT [EC:3.2.1.129] synonym: "endo-N-acylneuraminidase activity" EXACT [EC:3.2.1.129] synonym: "endoneuraminidase activity" EXACT [EC:3.2.1.129] synonym: "endosialidase activity" EXACT [EC:3.2.1.129] synonym: "poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase activity" EXACT [EC:3.2.1.129] synonym: "poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase activity" EXACT [EC:3.2.1.129] synonym: "polysialoside (2->8)-alpha-sialosylhydrolase activity" EXACT [EC:3.2.1.129] xref: EC:3.2.1.129 xref: GO:0016996 xref: MetaCyc:3.2.1.129-RXN is_a: CCO:F0003509 ! alpha-sialidase activity [Term] id: CCO:F0003509 name: alpha-sialidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids." [GOC:mah] subset: gosubset_prok xref: GO:0016997 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0003510 name: activin receptor activity namespace: molecular_function def: "Combining with activin, one of two gonadal glycoproteins related to transforming growth factor beta, to initiate a change in cell activity." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0017002 is_a: CCO:F0001354 ! transforming growth factor beta receptor activity [Term] id: CCO:F0003511 name: tyrosyl-DNA phosphodiesterase activity namespace: molecular_function def: "Catalysis of the hydrolysis of covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA." [PMID:10521354] comment: See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'. xref: GO:0017005 is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0003512 name: Ras GTPase binding namespace: molecular_function def: "Interacting selectively with any member of the Ras superfamily of monomeric GTPases." [GOC:mah] synonym: "Ras interactor activity" RELATED [] xref: GO:0017016 is_a: CCO:F0004648 ! small GTPase binding [Term] id: CCO:F0003513 name: MAP kinase tyrosine/serine/threonine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate." [GOC:mah, PMID:12184814] synonym: "dual-specificity MAP kinase phosphatase activity" EXACT [] xref: EC:3.1.3.- xref: GO:0017017 is_a: CCO:F0001741 ! protein tyrosine/serine/threonine phosphatase activity is_a: CCO:F0005176 ! MAP kinase phosphatase activity [Term] id: CCO:F0003514 name: myosin phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate." [EC:3.1.3.16] synonym: "myosin phosphatase myosin binding" RELATED [] synonym: "myosin phosphatase, intrinsic catalyst activity" EXACT [] xref: GO:0017018 xref: GO:0017019 is_a: CCO:F0001087 ! protein serine/threonine phosphatase activity [Term] id: CCO:F0003515 name: myosin phosphatase regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme myosin phosphatase." [EC:3.1.3.16, GOC:ai] synonym: "myosin phosphatase, intrinsic regulator activity" NARROW [] xref: GO:0017020 is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0003516 name: myosin binding namespace: molecular_function def: "Interacting selectively with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] synonym: "myosin phosphatase myosin binding" NARROW [] xref: GO:0017022 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0003517 name: myosin I binding namespace: molecular_function def: "Interacting selectively with a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments." [GOC:bf, GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0017024 is_a: CCO:F0003516 ! myosin binding [Term] id: CCO:F0003518 name: TATA-binding protein binding namespace: molecular_function def: "Interacting selectively with TATA-binding protein (TBP), a component of various transcription factors." [GOC:jl, http://www.mblab.gla.ac.uk/] synonym: "TBP binding" EXACT [] xref: GO:0017025 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0003519 name: procollagen C-endopeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III." [EC:3.4.24.19] synonym: "BMP1" NARROW [] synonym: "carboxyprocollagen peptidase activity" EXACT [EC:3.4.24.19] synonym: "procollagen C-proteinase activity" EXACT [EC:3.4.24.19] synonym: "procollagen C-terminal peptidase activity" EXACT [EC:3.4.24.19] synonym: "procollagen C-terminal proteinase activity" EXACT [EC:3.4.24.19] synonym: "procollagen carboxy-terminal proteinase activity" EXACT [EC:3.4.24.19] synonym: "procollagen carboxypeptidase activity" EXACT [EC:3.4.24.19] synonym: "procollagen peptidase activity" EXACT [EC:3.4.24.19] xref: EC:3.4.24.19 xref: GO:0017026 xref: MetaCyc:3.4.24.19-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0003520 name: potassium:amino acid symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in)." [GOC:ai] synonym: "potassium:amino acid transporter activity" BROAD [] xref: GO:0017032 is_a: CCO:F0001608 ! cation:amino acid symporter activity [Term] id: CCO:F0003521 name: DNA topoisomerase I binding namespace: molecular_function def: "Interacting selectively with the enzyme DNA topoisomerase I." [GOC:ai] xref: GO:0017033 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0003522 name: Rap guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase of the Rap family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] xref: GO:0017034 is_a: CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity [Term] id: CCO:F0003523 name: dipeptidyl-peptidase III activity namespace: molecular_function def: "Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides." [EC:3.4.14.4] subset: gosubset_prok synonym: "dipeptidyl aminopeptidase III activity" EXACT [EC:3.4.14.4] synonym: "dipeptidyl arylamidase III activity" EXACT [EC:3.4.14.4] synonym: "DPP III activity" EXACT [EC:3.4.14.4] synonym: "enkephalinase B activity" NARROW [EC:3.4.14.4] synonym: "red cell angiotensinase activity" NARROW [EC:3.4.14.4] xref: EC:3.4.14.4 xref: GO:0017039 xref: MetaCyc:3.4.14.4-RXN is_a: CCO:F0001789 ! dipeptidyl-peptidase activity [Term] id: CCO:F0003524 name: ceramidase activity namespace: molecular_function def: "Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine." [EC:3.5.1.23] subset: gosubset_prok synonym: "acylsphingosine deacylase activity" EXACT [EC:3.5.1.23] synonym: "glycosphingolipid ceramide deacylase" BROAD [EC:3.5.1.23] synonym: "N-acylsphingosine amidohydrolase activity" EXACT [EC:3.5.1.23] xref: EC:3.5.1.23 xref: GO:0017040 xref: MetaCyc:CERAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0003525 name: galactosylgalactosylglucosylceramidase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose." [EC:3.2.1.47] synonym: "ceramide trihexosidase activity" EXACT [EC:3.2.1.47] synonym: "ceramidetrihexosidase activity" EXACT [EC:3.2.1.47] synonym: "ceramidetrihexoside alpha-galactosidase activity" EXACT [EC:3.2.1.47] synonym: "D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase activity" EXACT [EC:3.2.1.47] synonym: "trihexosyl ceramide galactosidase activity" EXACT [EC:3.2.1.47] synonym: "trihexosylceramide alpha-galactosidase activity" EXACT [EC:3.2.1.47] xref: EC:3.2.1.47 xref: GO:0017041 xref: MetaCyc:3.2.1.47-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds is_a: CCO:F0003524 ! ceramidase activity [Term] id: CCO:F0003526 name: glycosylceramidase activity namespace: molecular_function def: "Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine." [EC:3.2.1.62] synonym: "cerebrosidase activity" EXACT [EC:3.2.1.62] synonym: "glycosyl ceramide glycosylhydrolase activity" EXACT [EC:3.2.1.62] synonym: "glycosyl-N-acylsphingosine glycohydrolase activity" EXACT [EC:3.2.1.62] synonym: "lactase-phlorizin hydrolase" BROAD [EC:3.2.1.62] synonym: "phloretin-glucosidase activity" EXACT [EC:3.2.1.62] synonym: "phloridzin beta-glucosidase activity" EXACT [EC:3.2.1.62] synonym: "phloridzin glucosidase activity" EXACT [EC:3.2.1.62] synonym: "phlorizin hydrolase activity" EXACT [EC:3.2.1.62] xref: EC:3.2.1.62 xref: GO:0017042 xref: MetaCyc:GLYCOSYLCERAMIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds is_a: CCO:F0003524 ! ceramidase activity [Term] id: CCO:F0003527 name: alpha-melanocyte stimulating hormone activity namespace: molecular_function synonym: "alpha-melanophore stimulating hormone activity" EXACT [] xref: GO:0017044 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0003528 name: adrenocorticotropin-releasing hormone activity namespace: molecular_function synonym: "corticotropin-releasing hormone" EXACT [] xref: GO:0017045 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0003529 name: peptide hormone binding namespace: molecular_function def: "Interacting selectively with any peptide with hormonal activity in animals." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "polypeptide hormone binding" EXACT [] xref: GO:0017046 is_a: CCO:F0005639 ! peptide binding is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0003530 name: adrenocorticotropin-releasing hormone binding namespace: molecular_function def: "Interacting selectively with adrenocorticotropin-releasing hormone." [GOC:jl] xref: GO:0017047 is_a: CCO:F0003529 ! peptide hormone binding [Term] id: CCO:F0003531 name: Rho GTPase binding namespace: molecular_function def: "Interacting selectively with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton." [ISBN:0198547684, PMID:12581856] synonym: "Rho interactor activity" RELATED [] synonym: "Rhophilin" NARROW [] xref: GO:0017031 xref: GO:0017048 is_a: CCO:F0003512 ! Ras GTPase binding [Term] id: CCO:F0003532 name: GTP-Rho binding namespace: molecular_function def: "Interacting selectively with the GTP-bound form of the Rho protein." [GOC:mah] xref: GO:0017049 is_a: CCO:F0003531 ! Rho GTPase binding [Term] id: CCO:F0003533 name: D-erythro-sphingosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP." [UniProtKB:Q9JIA7] synonym: "sphingosine kinase activity" EXACT [] xref: GO:0017050 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0003534 name: retinol dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol." [PMID:9857081] xref: GO:0017051 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003535 name: structural constituent of nuclear pore namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the nuclear pore complex." [GOC:mah] xref: GO:0017056 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0003536 name: 6-phosphogluconolactonase activity namespace: molecular_function def: "Catalysis of the reaction: 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate." [EC:3.1.1.31] subset: gosubset_prok synonym: "6-PGL" RELATED [EC:3.1.1.31] synonym: "6-phospho-D-glucono-1,5-lactone lactonohydrolase activity" EXACT [EC:3.1.1.31] synonym: "phosphogluconolactonase activity" EXACT [EC:3.1.1.31] xref: EC:3.1.1.31 xref: GO:0017057 xref: MetaCyc:6PGLUCONOLACT-RXN xref: Reactome:25159 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0003537 name: FH1 domain binding namespace: molecular_function def: "Interacting selectively with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain." [GOC:go_curators] xref: GO:0017058 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0003538 name: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.65] synonym: "(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65] synonym: "(Lea)-dependent (alpha-3/4)-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "alpha(1,3/1,4) fucosyltransferase III" RELATED [EC:2.4.1.65] synonym: "alpha(1,4)-L-fucosyltransferase activity" EXACT [] synonym: "alpha-(1,3/1,4) fucosyltransferase III activity" EXACT [EC:2.4.1.65] synonym: "alpha-(1->4)-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "alpha-4-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "beta-acetylglucosaminylsaccharide fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "blood group Lewis alpha-4-fucosyltransferase" NARROW [EC:2.4.1.65] synonym: "blood group Lewis alpha-4-fucosyltransferase activity" NARROW [EC:2.4.1.65] synonym: "blood-group substance Le(a)-dependent fucosyltransferase activity" NARROW [EC:2.4.1.65] synonym: "blood-group substance Lea-dependent fucosyltransferase" NARROW [EC:2.4.1.65] synonym: "FucT-II activity" EXACT [EC:2.4.1.65] synonym: "galactoside 3(4)-L-fucosyltransferase activity" EXACT [] synonym: "GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] synonym: "Lewis alpha-(1->3/4)-fucosyltransferase" NARROW [EC:2.4.1.65] synonym: "Lewis alpha-(1->3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65] synonym: "Lewis blood group alpha-(1->3/4)-fucosyltransferase" NARROW [EC:2.4.1.65] synonym: "Lewis blood group alpha-(1->3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65] synonym: "Lewis FT activity" NARROW [EC:2.4.1.65] synonym: "Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase" NARROW [EC:2.4.1.65] synonym: "Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity" NARROW [EC:2.4.1.65] xref: EC:2.4.1.65 xref: GO:0017060 xref: MetaCyc:2.4.1.65-RXN is_a: CCO:F0001884 ! fucosyltransferase activity [Term] id: CCO:F0003539 name: S-methyl-5-thioadenosine phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate." [EC:2.4.2.28] subset: gosubset_prok synonym: "5'-deoxy-5'-methylthioadenosine phosphorylase activity" EXACT [EC:2.4.2.28] synonym: "5'-methylthioadenosine phosphorylase activity" EXACT [] synonym: "5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase activity" EXACT [EC:2.4.2.28] synonym: "MeSAdo phosphorylase activity" EXACT [EC:2.4.2.28] synonym: "MeSAdo/Ado phosphorylase activity" EXACT [EC:2.4.2.28] synonym: "methylthioadenosine nucleoside phosphorylase activity" EXACT [EC:2.4.2.28] synonym: "methylthioadenosine phosphorylase activity" EXACT [EC:2.4.2.28] synonym: "MTA phosphorylase activity" EXACT [EC:2.4.2.28] synonym: "MTAPase activity" EXACT [EC:2.4.2.28] synonym: "S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity" EXACT [EC:2.4.2.28] xref: EC:2.4.2.28 xref: GO:0017061 xref: MetaCyc:5 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0003540 name: phosphatidylserine-specific phospholipase A1 activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion." [EC:3.1.1.32] xref: GO:0017063 is_a: CCO:F0002303 ! phospholipase A1 activity [Term] id: CCO:F0003541 name: fatty acid amide hydrolase activity namespace: molecular_function xref: GO:0017064 xref: GO:0017073 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0003542 name: single-strand selective uracil DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA." [GOC:elh, PMID:9224623] synonym: "single-strand selective monofunctional uracil-DNA glycosylase activity" EXACT [] xref: EC:3.2.2.- xref: GO:0017065 xref: Reactome:25182 is_a: CCO:F0001200 ! uracil DNA N-glycosylase activity [Term] id: CCO:F0003543 name: tyrosine-ester sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate." [EC:2.8.2.9] synonym: "3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase activity" EXACT [EC:2.8.2.9] synonym: "aryl sulfotransferase IV" RELATED [EC:2.8.2.9] synonym: "L-tyrosine methyl ester sulfotransferase activity" EXACT [EC:2.8.2.9] synonym: "tyrosine-ester sulphotransferase activity" EXACT [] xref: EC:2.8.2.9 xref: GO:0008128 xref: GO:0017067 xref: MetaCyc:TYROSINE-ESTER-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0003544 name: snRNA binding namespace: molecular_function def: "Interacting selectively with a small nuclear RNA (snRNA)." [GOC:mah] synonym: "small nuclear RNA binding" EXACT [] xref: GO:0017069 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0003545 name: U6 snRNA binding namespace: molecular_function def: "Interacting selectively with the U6 small nuclear RNA (U6 snRNA)." [GOC:mah] comment: Note that this term may be useful for annotating small nuclear RNAs (snRNAs). xref: GO:0017070 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0003546 name: procollagen N-endopeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln." [EC:3.4.24.14] synonym: "aminoprocollagen peptidase activity" EXACT [EC:3.4.24.14] synonym: "aminoterminal procollagen peptidase activity" EXACT [EC:3.4.24.14] synonym: "procollagen aminopeptidase activity" EXACT [EC:3.4.24.14] synonym: "procollagen aminoterminal protease activity" EXACT [EC:3.4.24.14] synonym: "procollagen N-proteinase activity" EXACT [EC:3.4.24.14] synonym: "procollagen N-terminal peptidase activity" EXACT [EC:3.4.24.14] synonym: "procollagen N-terminal proteinase activity" EXACT [EC:3.4.24.14] synonym: "type I/II procollagen N-proteinase activity" EXACT [EC:3.4.24.14] synonym: "type III procollagen" RELATED [EC:3.4.24.14] xref: EC:3.4.24.14 xref: GO:0017074 xref: MetaCyc:3.4.24.14-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0003547 name: syntaxin-1 binding namespace: molecular_function def: "Interacting selectively with the SNAP receptor syntaxin-1." [GOC:ai] xref: GO:0017075 is_a: CCO:F0004214 ! syntaxin binding [Term] id: CCO:F0003548 name: purine nucleotide binding namespace: molecular_function def: "Interacting selectively with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate." [GOC:ai] subset: gosubset_prok xref: GO:0017076 is_a: CCO:F0000031 ! nucleotide binding [Term] id: CCO:F0003549 name: oxidative phosphorylation uncoupler activity namespace: molecular_function def: "Catalysis of the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis." [PMID:15738989, PMID:16179945] synonym: "mitochondrial uncoupling protein activity" NARROW [] synonym: "uncoupling protein activity" NARROW [] xref: GO:0015302 xref: GO:0017077 is_a: CCO:F0004284 ! transmembrane transporter activity [Term] id: CCO:F0003550 name: Hsc70 protein regulator activity namespace: molecular_function def: "Binds to and modulates the activity of the molecular chaperone Hsc70." [GOC:jl, PMID:11121403] synonym: "Hsc70 interacting protein" BROAD [] xref: GO:0017078 is_a: CCO:F0004345 ! Hsp70/Hsc70 protein regulator activity is_a: CCO:F0004456 ! Hsp70 protein binding [Term] id: CCO:F0003551 name: sodium channel regulator activity namespace: molecular_function xref: GO:0017080 is_a: CCO:F0003086 ! channel regulator activity [Term] id: CCO:F0003552 name: chloride channel regulator activity namespace: molecular_function xref: GO:0017081 is_a: CCO:F0003086 ! channel regulator activity [Term] id: CCO:F0003553 name: mineralocorticoid receptor activity namespace: molecular_function def: "Combining with mineralocorticoid to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0017082 is_a: CCO:F0000295 ! steroid hormone receptor activity [Term] id: CCO:F0003554 name: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R." [EC:2.4.1.152] synonym: "galactoside 3-fucosyltransferase activity" EXACT [EC:2.4.1.152] synonym: "galactoside 3-L-fucosyltransferase activity" EXACT [] synonym: "GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.152] synonym: "GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity" EXACT [EC:2.4.1.152] synonym: "GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity" EXACT [EC:2.4.1.152] synonym: "guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase activity" EXACT [EC:2.4.1.152] synonym: "guanosine diphosphofucose-glucoside alpha1->3-fucosyltransferase activity" EXACT [EC:2.4.1.152] synonym: "lewis-negative alpha-3-fucosyltransferase activity" EXACT [EC:2.4.1.152] synonym: "Lewis-negative alpha-3-fucosyltransferase activity" NARROW [EC:2.4.1.152] synonym: "plasma alpha-3-fucosyltransferase activity" NARROW [EC:2.4.1.152] xref: EC:2.4.1.152 xref: GO:0017083 xref: MetaCyc:GALACTOSIDE-3-FUCOSYLTRANSFERASE-RXN is_a: CCO:F0006272 ! alpha(1,3)-fucosyltransferase activity [Term] id: CCO:F0003555 name: delta1-pyrroline-5-carboxylate synthetase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate." [MetaCyc:PROLINE-MULTI] synonym: "D1-pyrroline-5-carboxylate synthetase activity" EXACT [] xref: GO:0017084 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003556 name: X-Pro dipeptidyl-peptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile." [EC:3.4.14.11] subset: gosubset_prok synonym: "PepX" RELATED [EC:3.4.14.11] synonym: "X-prolyl dipeptidyl aminopeptidase activity" EXACT [EC:3.4.14.11] synonym: "X-prolyl dipeptidyl peptidase activity" EXACT [EC:3.4.14.11] synonym: "Xaa-Pro dipeptidyl-peptidase activity" EXACT [] xref: EC:3.4.14.11 xref: GO:0017088 xref: MetaCyc:3.4.14.11-RXN is_a: CCO:F0001789 ! dipeptidyl-peptidase activity [Term] id: CCO:F0003557 name: glycolipid transporter activity namespace: molecular_function def: "Enables the directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of, within or between cells." [GOC:ai] xref: GO:0017089 is_a: CCO:F0001556 ! lipid transporter activity [Term] id: CCO:F0003558 name: AU-rich element binding namespace: molecular_function def: "Interacting selectively with AU-rich elements within the 3' untranslated region of mRNAs." [GOC:mah, PMID:7892223] synonym: "ARE binding" EXACT [] synonym: "AU-specific RNA binding" EXACT [] xref: GO:0017091 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0003559 name: sterol regulatory element-binding protein site 2 protease activity namespace: molecular_function def: "Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus." [GOC:bf, PMID:12923525] synonym: "SREBP site 2 protease activity" EXACT [] xref: GO:0017092 is_a: CCO:F0001787 ! metallopeptidase activity is_a: CCO:F0003560 ! sterol regulatory element-binding protein protease activity [Term] id: CCO:F0003560 name: sterol regulatory element-binding protein protease activity namespace: molecular_function def: "Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, PMID:12923525] synonym: "SREBP protease activity" EXACT [] xref: GO:0017093 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0003561 name: sterol regulatory element-binding protein site 1 protease activity namespace: molecular_function def: "Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves." [GOC:bf, PMID:12923525] synonym: "SREBP site 1 protease activity" EXACT [] xref: GO:0017094 is_a: CCO:F0001786 ! serine-type peptidase activity is_a: CCO:F0003560 ! sterol regulatory element-binding protein protease activity [Term] id: CCO:F0003562 name: heparan sulfate 6-O-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate." [PMID:8631808] synonym: "heparan sulphate 6-O-sulphotransferase activity" EXACT [] synonym: "heparin 6-O-sulfotransferase activity" RELATED [] xref: EC:2.8.2.- xref: GO:0017095 is_a: CCO:F0008398 ! heparan sulfate sulfotransferase activity [Term] id: CCO:F0003563 name: acetylserotonin O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin (N-acetyl-5-methoxytryptamine)." [EC:2.1.1.4] subset: gosubset_prok synonym: "acetylserotonin methyltransferase activity" EXACT [EC:2.1.1.4] synonym: "hydroxyindole methyltransferase activity" EXACT [EC:2.1.1.4] synonym: "hydroxyindole O-methyltransferase activity" EXACT [EC:2.1.1.4] synonym: "N-acetylserotonin O-methyltransferase activity" EXACT [EC:2.1.1.4] synonym: "S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity" EXACT [EC:2.1.1.4] xref: EC:2.1.1.4 xref: GO:0017096 xref: MetaCyc:ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003564 name: acetylserotonin N-methyltransferase activity namespace: molecular_function xref: GO:0017097 is_a: CCO:F0001757 ! N-methyltransferase activity [Term] id: CCO:F0003565 name: sulfonylurea receptor binding namespace: molecular_function def: "Interacting selectively with the sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel." [GOC:ceb, PMID:11938023] synonym: "sulfonylurea receptor ligand" NARROW [] synonym: "sulphonylurea receptor binding" EXACT [] xref: GO:0017098 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0003566 name: very-long-chain-acyl-CoA dehydrogenase activity namespace: molecular_function xref: EC:1.3.99.- xref: GO:0017099 is_a: CCO:F0000480 ! acyl-CoA dehydrogenase activity [Term] id: CCO:F0003567 name: aminoacyl-tRNA synthetase auxiliary protein activity namespace: molecular_function xref: GO:0017100 is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0003568 name: UTP:galactose-1-phosphate uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UTP + alpha-D-galactose 1-phosphate = diphosphate + UDP-galactose." [EC:2.7.7.10] synonym: "alpha-D-galactose 1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] synonym: "Gal-1-P uridylyltransferase activity" BROAD [EC:2.7.7.10] synonym: "galactose 1-phosphate uridyltransferase activity" EXACT [EC:2.7.7.10] synonym: "galactose 1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] synonym: "galactose-1-phosphate uridylyltransferase activity" BROAD [EC:2.7.7.10] synonym: "UDPgalactose pyrophosphorylase activity" EXACT [EC:2.7.7.10] synonym: "uridine diphosphate galactose pyrophosphorylase activity" EXACT [EC:2.7.7.10] synonym: "uridine diphosphogalactose pyrophosphorylase activity" EXACT [EC:2.7.7.10] synonym: "UTP-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] synonym: "UTP:alpha-D-hexose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.10] synonym: "UTP:hexose-1-phosphate uridylyltransferase activity" BROAD [] xref: EC:2.7.7.10 xref: GO:0003982 xref: GO:0017103 xref: MetaCyc:UTPHEXPURIDYLYLTRANS-RXN is_a: CCO:F0008184 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity [Term] id: CCO:F0003569 name: acyl-CoA delta11-desaturase activity namespace: molecular_function synonym: "acyl-CoA D11-desaturase activity" EXACT [] synonym: "acyl-CoA delta(11)-desaturase activity" EXACT [] xref: GO:0017105 is_a: CCO:F0003074 ! CoA desaturase activity [Term] id: CCO:F0003570 name: activin inhibitor activity namespace: molecular_function def: "Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0017106 is_a: CCO:F0001225 ! signal transducer activity [Term] id: CCO:F0003571 name: anion exchanger adaptor activity namespace: molecular_function def: "The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way." [GOC:mtg_MIT] xref: GO:0017107 is_a: CCO:F0002805 ! anion exchanger activity is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0003572 name: 5'-flap endonuclease activity namespace: molecular_function def: "Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis." [PMID:9778254, UniProtKB:P39749] synonym: "5' flap endonuclease activity" EXACT [] xref: GO:0017108 xref: Reactome:25632 is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters is_a: CCO:F0007325 ! flap endonuclease activity [Term] id: CCO:F0003573 name: nucleoside-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate." [EC:3.6.1.6] synonym: "apyrase activity" BROAD [] synonym: "CDPase" NARROW [EC:3.6.1.6] synonym: "IDPase" NARROW [EC:3.6.1.6] synonym: "inosine 5'-diphosphatase" NARROW [EC:3.6.1.6] synonym: "inosine diphosphatase" NARROW [EC:3.6.1.6] synonym: "NDPase activity" EXACT [EC:3.6.1.6] synonym: "nucleoside 5'-diphosphatase activity" EXACT [EC:3.6.1.6] synonym: "nucleoside diphosphatase activity" EXACT [] synonym: "nucleoside diphosphate phosphatase activity" EXACT [EC:3.6.1.6] synonym: "nucleoside diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.6] synonym: "nucleoside-diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.6] synonym: "type B nucleoside diphosphatase" NARROW [EC:3.6.1.6] synonym: "type L nucleoside diphosphatase" NARROW [EC:3.6.1.6] xref: EC:3.6.1.6 xref: GO:0017110 xref: MetaCyc:NUCLEOSIDE-DIPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0003574 name: nucleoside-triphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate." [EC:3.6.1.15] subset: gosubset_prok synonym: "apyrase activity" BROAD [] synonym: "NTPase activity" EXACT [EC:3.6.1.15] synonym: "nucleoside 5-triphosphatase activity" EXACT [EC:3.6.1.15] synonym: "nucleoside triphosphatase activity" EXACT [] synonym: "nucleoside triphosphate hydrolase activity" EXACT [EC:3.6.1.15] synonym: "nucleoside triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.15] synonym: "nucleoside-5-triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.15] synonym: "unspecific diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.15] xref: EC:3.6.1.15 xref: GO:0017111 xref: MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0003575 name: Rab guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase of the Rab family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] xref: GO:0017112 is_a: CCO:F0001393 ! Ras guanyl-nucleotide exchange factor activity [Term] id: CCO:F0003576 name: dihydropyrimidine dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+." [EC:1.3.1.2] subset: gosubset_prok synonym: "4,5-dihydrothymine: oxidoreductase activity" EXACT [EC:1.3.1.2] synonym: "5,6-dihydrouracil:NADP+ 5-oxidoreductase activity" EXACT [EC:1.3.1.2] synonym: "dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.3.1.2] synonym: "DHPDH" RELATED [EC:1.3.1.2] synonym: "DHU dehydrogenase activity" EXACT [EC:1.3.1.2] synonym: "dihydropyrimidine dehydrogenase activity" EXACT [] synonym: "dihydrothymine dehydrogenase activity" RELATED [EC:1.3.1.2] synonym: "dihydrouracil dehydrogenase (NADP)" EXACT [EC:1.3.1.2] synonym: "dihydrouracil dehydrogenase (NADP+) activity" EXACT [EC:1.3.1.2] synonym: "DPD" RELATED [EC:1.3.1.2] synonym: "hydropyrimidine dehydrogenase activity" EXACT [EC:1.3.1.2] xref: EC:1.3.1.2 xref: GO:0017113 xref: MetaCyc:1.3.1.2-RXN xref: Reactome:25636 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003577 name: wide-spectrum protease inhibitor activity namespace: molecular_function synonym: "wide-spectrum proteinase inhibitor" EXACT [] xref: GO:0017114 is_a: CCO:F0001222 ! endopeptidase inhibitor activity [Term] id: CCO:F0003578 name: single-stranded DNA-dependent ATP-dependent DNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. xref: GO:0017116 is_a: CCO:F0000487 ! ATP-dependent DNA helicase activity is_a: CCO:F0005804 ! single-stranded DNA-dependent ATPase activity [Term] id: CCO:F0003579 name: lipoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme." [PMID:10103005] subset: gosubset_prok xref: GO:0017118 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0003580 name: polyphosphoinositide phosphatase activity namespace: molecular_function def: "Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization." [PMID:10224048] xref: GO:0017120 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0003581 name: Ral GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by a GTPase of the Ral family." [GOC:mah] xref: GO:0017123 is_a: CCO:F0001404 ! Ras GTPase activator activity [Term] id: CCO:F0003582 name: SH3 domain binding namespace: molecular_function def: "Interacting selectively with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins." [GOC:go_curators, Pfam:PF00018] xref: GO:0017124 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0003583 name: deoxycytidyl transferase activity namespace: molecular_function def: "Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA." [PMID:10535901] synonym: "deoxycytidyl transferase activity, template-dependent" NARROW [] xref: GO:0017125 xref: GO:0019986 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0003584 name: cholesterol transporter activity namespace: molecular_function def: "Enables the directed movement of cholesterol into, out of, within or between cells. Cholesterol is the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones." [GOC:ai] xref: GO:0017127 is_a: CCO:F0002716 ! sterol transporter activity [Term] id: CCO:F0003585 name: phospholipid scramblase activity namespace: molecular_function xref: GO:0017128 is_a: CCO:F0001671 ! phospholipid transporter activity [Term] id: CCO:F0003586 name: triglyceride binding namespace: molecular_function def: "Interacting selectively with any triester of glycerol." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0017129 is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0003587 name: poly(rC) binding namespace: molecular_function def: "Interacting selectively with a sequence of cytosine residues in an RNA molecule." [GOC:mah] xref: GO:0017130 is_a: CCO:F0000312 ! single-stranded RNA binding [Term] id: CCO:F0003588 name: uridine-rich cytoplasmic polyadenylylation element binding namespace: molecular_function def: "Interacting selectively with U-rich sequence in the 3'-end of mRNAs; required for cytoplasmic polyadenylylation." [PMID:7954828] synonym: "uridine-rich cytoplasmic polyadenylation element binding" EXACT [] xref: GO:0017131 is_a: CCO:F0001768 ! poly-pyrimidine tract binding [Term] id: CCO:F0003589 name: cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase; dependent on the presence of a cyclic nucleotide." [GOC:mah, PMID:9856955] xref: GO:0017132 is_a: CCO:F0001390 ! guanyl-nucleotide exchange factor activity [Term] id: CCO:F0003590 name: fibroblast growth factor binding namespace: molecular_function def: "Interacting selectively with fibroblast growth factor." [PMID:9806903] synonym: "FGF binding" EXACT [] xref: GO:0017134 is_a: CCO:F0004188 ! growth factor binding [Term] id: CCO:F0003591 name: NAD-dependent histone deacetylase activity namespace: molecular_function def: "Catalysis of the removal of acetyl groups from histones, requiring NAD." [GOC:ai] synonym: "SIR2" RELATED [] xref: GO:0017136 is_a: CCO:F0000816 ! histone deacetylase activity [Term] id: CCO:F0003592 name: Rab GTPase binding namespace: molecular_function def: "Interacting selectively with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases." [GOC:mah] synonym: "Rab escort protein activity" NARROW [] synonym: "Rab interactor activity" RELATED [] synonym: "REP" NARROW [] xref: GO:0005084 xref: GO:0017137 is_a: CCO:F0001388 ! small GTPase regulator activity is_a: CCO:F0003512 ! Ras GTPase binding [Term] id: CCO:F0003593 name: lipoic acid synthase activity namespace: molecular_function def: "Catalysis of the reaction: octanoic acid + 2 S = lipoic acid + 2 H." [PMID:11106496, PMID:11389890] subset: gosubset_prok xref: GO:0017140 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0003594 name: Wnt-protein binding namespace: molecular_function def: "Interacting selectively with Wnt-protein, a secreted growth factor involved in signaling." [GOC:jl] xref: GO:0017147 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0003595 name: tRNA dihydrouridine synthase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor." [PMID:11983710] subset: gosubset_prok xref: GO:0017150 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003596 name: DEAD/H-box RNA helicase binding namespace: molecular_function def: "Interacting selectively with the enzyme DEAD/H-box RNA helicase." [GOC:jl] xref: GO:0017151 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0003597 name: sodium:dicarboxylate symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in)." [GOC:ai] subset: gosubset_prok synonym: "sodium:dicarboxylate cotransporter activity" EXACT [] xref: GO:0017153 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity is_a: CCO:F0001571 ! organic acid:sodium symporter activity is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0003598 name: semaphorin receptor activity namespace: molecular_function xref: GO:0017154 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0003599 name: pantetheine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-pantetheine + H2O = (R)-pantothenate + 2-aminoethanethiol." [EC:3.5.1.92] synonym: "(R)-pantetheine amidohydrolase activity" EXACT [EC:3.5.1.92] synonym: "pantetheinase activity" EXACT [EC:3.5.1.92] synonym: "vanin" RELATED [EC:3.5.1.92] synonym: "vanin-1" RELATED [EC:3.5.1.92] xref: EC:3.5.1.92 xref: GO:0017159 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0003600 name: Ral GTPase binding namespace: molecular_function def: "Interacting selectively with Ral protein, any member of the Ral subfamily of the Ras superfamily of monomeric GTPases." [GOC:mah] synonym: "Ral interactor activity" RELATED [] xref: GO:0017160 is_a: CCO:F0003512 ! Ras GTPase binding [Term] id: CCO:F0003601 name: inositol-1,3,4-trisphosphate 4-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate." [GOC:ai] xref: EC:3.1.3.- xref: GO:0017161 is_a: CCO:F0006172 ! inositol trisphosphate phosphatase activity [Term] id: CCO:F0003602 name: aryl hydrocarbon receptor binding namespace: molecular_function def: "Interacting selectively with an aryl hydrocarbon receptor." [GOC:ai] xref: GO:0017162 is_a: CCO:F0001407 ! receptor binding is_a: CCO:F0001738 ! transcription factor binding [Term] id: CCO:F0003603 name: negative regulator of basal transcription activity namespace: molecular_function subset: gosubset_prok xref: GO:0017163 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0003604 name: dipeptidase E activity namespace: molecular_function def: "Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides." [EC:3.4.13.21] subset: gosubset_prok synonym: "alpha-aspartyl dipeptidase activity" EXACT [] synonym: "aspartyl dipeptidase activity" EXACT [EC:3.4.13.21] synonym: "PepE gene product (Salmonella typhimurium) activity" NARROW [EC:3.4.13.21] synonym: "peptidase E activity" BROAD [EC:3.4.13.21] xref: EC:3.4.13.21 xref: GO:0017165 xref: MetaCyc:3.4.13.21-RXN is_a: CCO:F0003375 ! dipeptidase activity [Term] id: CCO:F0003605 name: vinculin binding namespace: molecular_function def: "Interacting selectively with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0017166 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0003606 name: 5-oxoprolinase (ATP-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate." [EC:3.5.2.9] subset: gosubset_prok synonym: "5-OPase activity" EXACT [EC:3.5.2.9] synonym: "5-oxo-L-prolinase activity" EXACT [EC:3.5.2.9] synonym: "5-oxo-L-proline amidohydrolase (ATP-hydrolysing)" EXACT [EC:3.5.2.9] synonym: "5-oxoprolinase (ATP-hydrolysing)" EXACT [EC:3.5.2.9] synonym: "5-oxoprolinase activity" EXACT [EC:3.5.2.9] synonym: "L-pyroglutamate hydrolase activity" EXACT [EC:3.5.2.9] synonym: "oxoprolinase activity" EXACT [EC:3.5.2.9] synonym: "pyroglutamase (ATP-hydrolysing)" EXACT [EC:3.5.2.9] synonym: "pyroglutamase (ATP-hydrolyzing) activity" EXACT [EC:3.5.2.9] synonym: "pyroglutamase activity" EXACT [EC:3.5.2.9] synonym: "pyroglutamate hydrolase activity" EXACT [EC:3.5.2.9] synonym: "pyroglutamic hydrolase activity" EXACT [EC:3.5.2.9] xref: EC:3.5.2.9 xref: GO:0017168 xref: MetaCyc:5-OXOPROLINASE-(ATP-HYDROLYSING)-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0003607 name: CDP-alcohol phosphatidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol." [GOC:ai] subset: gosubset_prok xref: GO:0017169 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0003608 name: KU70 binding namespace: molecular_function def: "Interacting selectively with Ku70, a protein involved in non-homologous DNA end joining." [GOC:mah, PMID:14739985] xref: GO:0017170 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0003609 name: serine hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [http://en.wikipedia.org/wiki/Serine_hydrolase] xref: GO:0017171 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0003610 name: cysteine dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-cysteine + O2 = 3-sulfinoalanine." [EC:1.13.11.20] subset: gosubset_prok xref: EC:1.13.11.20 xref: GO:0017172 xref: MetaCyc:CYSTEINE-DIOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003611 name: DRAP deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate." [GOC:jl, MetaCyc:YOL066C-MONOMER] xref: GO:0017173 is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0003612 name: glycine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine." [EC:2.1.1.20] synonym: "glycine methyltransferase activity" EXACT [EC:2.1.1.20] synonym: "GNMT" RELATED [EC:2.1.1.20] synonym: "S-adenosyl-L-methionine:glycine methyltransferase activity" EXACT [EC:2.1.1.20] synonym: "S-adenosyl-L-methionine:glycine N-methyltransferase activity" EXACT [EC:2.1.1.20] xref: EC:2.1.1.20 xref: GO:0017174 xref: MetaCyc:GLYCINE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003613 name: phosphatidylinositol N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol." [EC:2.4.1.198] synonym: "UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase activity" EXACT [EC:2.4.1.198] synonym: "UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.198] synonym: "uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.198] synonym: "uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.198] xref: EC:2.4.1.198 xref: GO:0017176 xref: MetaCyc:2.4.1.198-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0003614 name: diphthine-ammonia ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + diphthine + NH3 = ADP + phosphate + diphthamide." [EC:6.3.2.22] synonym: "diphthamide synthase activity" EXACT [EC:6.3.2.22] synonym: "diphthamide synthetase activity" EXACT [EC:6.3.2.22] synonym: "diphthine:ammonia ligase (ADP-forming)" EXACT [EC:6.3.2.22] xref: EC:6.3.2.22 xref: GO:0017178 xref: MetaCyc:DIPHTINE--AMMONIA-LIGASE-RXN is_a: CCO:F0003071 ! ammonia ligase activity [Term] id: CCO:F0003615 name: aspartate N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-aspartate = CoA + N-acetyl-L-aspartate." [EC:2.3.1.17] synonym: "acetyl-CoA:L-aspartate N-acetyltransferase activity" EXACT [EC:2.3.1.17] synonym: "aspartate acetyltransferase activity" EXACT [EC:2.3.1.17] synonym: "L-aspartate N-acetyltransferase activity" EXACT [EC:2.3.1.17] xref: EC:2.3.1.17 xref: GO:0017188 xref: MetaCyc:ASPARTATE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0003616 name: glycoprotein N-palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein." [EC:2.3.1.96] synonym: "mucus glycoprotein fatty acyltransferase" NARROW [EC:2.3.1.96] synonym: "palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity" EXACT [EC:2.3.1.96] xref: EC:2.3.1.96 xref: GO:0018010 xref: MetaCyc:GLYCOPROTEIN-N-PALMITOYLTRANSFERASE-RXN is_a: CCO:F0004052 ! N-palmitoyltransferase activity [Term] id: CCO:F0003617 name: histone-lysine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives." [EC:2.1.1.43, RESID:AA0074, RESID:AA0075, RESID:AA0076] synonym: "histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity" EXACT [EC:2.1.1.43] synonym: "protein (lysine) methyltransferase activity" EXACT [EC:2.1.1.43] synonym: "protein methylase 3 activity" NARROW [EC:2.1.1.43] synonym: "protein methylase III activity" NARROW [EC:2.1.1.43] synonym: "protein methyltransferase II activity" NARROW [EC:2.1.1.43] synonym: "S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.43] synonym: "S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.43] xref: EC:2.1.1.43 xref: GO:0018024 xref: MetaCyc:HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN xref: RESID:AA0074 xref: RESID:AA0075 xref: RESID:AA0076 is_a: CCO:F0003100 ! protein-lysine N-methyltransferase activity is_a: CCO:F0005616 ! histone methyltransferase activity [Term] id: CCO:F0003618 name: calmodulin-lysine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine." [EC:2.1.1.60] synonym: "S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.60] synonym: "S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.60] synonym: "S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity" EXACT [EC:2.1.1.60] xref: EC:2.1.1.60 xref: GO:0018025 xref: MetaCyc:2.1.1.60-RXN is_a: CCO:F0003100 ! protein-lysine N-methyltransferase activity [Term] id: CCO:F0003619 name: peptidyl-lysine N6-myristoyltransferase activity namespace: molecular_function xref: EC:2.3.1.- xref: GO:0018030 is_a: CCO:F0000797 ! glycylpeptide N-tetradecanoyltransferase activity [Term] id: CCO:F0003620 name: peptidyl-lysine N6-palmitoyltransferase activity namespace: molecular_function xref: EC:2.3.1.- xref: GO:0018031 is_a: CCO:F0004052 ! N-palmitoyltransferase activity [Term] id: CCO:F0003621 name: protein-histidine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N-methyl-L-histidine." [EC:2.1.1.85] synonym: "actin-specific histidine methyltransferase activity" EXACT [EC:2.1.1.85] synonym: "peptidyl-histidine N-methyltransferase activity" EXACT [] synonym: "protein (histidine) methyltransferase activity" EXACT [EC:2.1.1.85] synonym: "protein methylase IV activity" NARROW [EC:2.1.1.85] synonym: "S-adenosyl methionine:protein-histidine N-methyltransferase activity" EXACT [EC:2.1.1.85] synonym: "S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase activity" EXACT [EC:2.1.1.85] xref: EC:2.1.1.85 xref: GO:0018064 xref: MetaCyc:2.1.1.85-RXN is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003622 name: NAD(P)-cysteine ADP-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine." [EC:2.4.2.-] xref: EC:2.4.2.- xref: GO:0018071 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0003623 name: histone arginine kinase activity namespace: molecular_function synonym: "histone-arginine kinase activity" EXACT [] xref: EC:2.7.3.- xref: GO:0018110 is_a: CCO:F0000529 ! arginine kinase activity is_a: CCO:F0005564 ! histone kinase activity [Term] id: CCO:F0003624 name: methionine racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine = D-methionine." [EC:5.1.1.2] xref: EC:5.1.1.2 xref: GO:0018111 xref: MetaCyc:METHIONINE-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0003625 name: proline racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-proline = D-proline." [EC:5.1.1.4] subset: gosubset_prok xref: EC:5.1.1.4 xref: GO:0018112 xref: MetaCyc:PROLINE-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0003626 name: lysine racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine = D-lysine." [EC:5.1.1.5] xref: EC:5.1.1.5 xref: GO:0018113 xref: MetaCyc:LYSINE-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0003627 name: threonine racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-threonine = D-threonine." [EC:5.1.1.6] xref: EC:5.1.1.6 xref: GO:0018114 xref: MetaCyc:THREONINE-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0003628 name: NAD(P)-asparagine ADP-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine." [EC:2.4.2.-] xref: EC:2.4.2.- xref: GO:0018121 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0003629 name: NAD(P)-serine ADP-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine." [EC:2.4.2.-] xref: EC:2.4.2.- xref: GO:0018127 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0003630 name: peptidyl-serine cyclase activity namespace: molecular_function xref: EC:4.2.1.- xref: GO:0018128 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003631 name: peptidyl-oxazoline dehydrogenase activity namespace: molecular_function xref: EC:1.3.-.- xref: GO:0018129 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003632 name: peptidyl-cysteine cyclase activity namespace: molecular_function xref: EC:4.2.1.- xref: GO:0018135 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003633 name: peptidyl-thiazoline dehydrogenase activity namespace: molecular_function xref: EC:1.3.-.- xref: GO:0018136 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003634 name: ribosomal S6-glutamic acid ligase activity namespace: molecular_function xref: EC:6.3.2.- xref: GO:0018169 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0003635 name: ribulose-bisphosphate carboxylase activase activity namespace: molecular_function xref: EC:6.3.-.- xref: GO:0018236 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003636 name: urease activase activity namespace: molecular_function xref: EC:6.3.-.- xref: GO:0018237 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003637 name: biotin-protein ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein." [GOC:mah] subset: gosubset_prok synonym: "biotin-apoprotein ligase activity" EXACT [] xref: EC:6.3.4.- xref: GO:0000106 xref: GO:0018271 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0003638 name: protein-serine epimerase activity namespace: molecular_function def: "Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine." [EC:5.1.1.16] synonym: "protein-serine racemase activity" EXACT [EC:5.1.1.16] xref: EC:5.1.1.16 xref: GO:0018365 xref: MetaCyc:5.1.1.16-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0003639 name: glycoprotein 3-alpha-L-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-L-fucose + N4-{N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-N-acetyl-beta-D-glucosaminyl}asparagine = GDP + N4-{N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosaminyl}asparagine." [EC:2.4.1.214] synonym: "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-peptide) alpha-1->3-fucosyltransferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6-GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-L-fucose:asparagine-linked N-acetylglucosamine alpha(1,3)-fucosyltransferase activity" EXACT [] synonym: "GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity" EXACT [EC:2.4.1.214] synonym: "GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity" EXACT [EC:2.4.1.214] xref: EC:2.4.1.214 xref: GO:0018392 xref: MetaCyc:2.4.1.214-RXN is_a: CCO:F0006272 ! alpha(1,3)-fucosyltransferase activity [Term] id: CCO:F0003640 name: UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity namespace: molecular_function xref: EC:2.7.8.- xref: GO:0018421 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0003641 name: GDP-mannose:serine-protein mannose-1-phosphotransferase activity namespace: molecular_function xref: EC:2.7.8.- xref: GO:0018422 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0003642 name: protein-leucine O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester; this reaction is the methylation of peptidyl-L-leucine to form peptidyl-L-leucine methyl ester." [PMID:8514774] synonym: "protein phosphatase methyltransferase activity" NARROW [] xref: EC:2.1.1.- xref: GO:0018423 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0001813 ! protein methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003643 name: prothoracicotrophic hormone activity namespace: molecular_function xref: GO:0018445 is_a: CCO:F0001481 ! neuropeptide hormone activity [Term] id: CCO:F0003644 name: pinocarveol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-." [UM-BBD_enzymeID:e0449] xref: EC:1.1.-.- xref: GO:0018446 xref: UM-BBD_enzymeID:e0449 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003645 name: chloral hydrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: chloral hydrate = 3 H+ + 2 e- + trichloroacetate OR chloral hydrate + H2 = H2O + trichloroethanol." [UM-BBD_enzymeID:e0229] xref: EC:1.1.-.- xref: GO:0018447 xref: UM-BBD_enzymeID:e0229 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003646 name: hydroxymethylmethylsilanediol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O." [UM-BBD_enzymeID:e0326] xref: EC:1.1.-.- xref: GO:0018448 xref: UM-BBD_enzymeID:e0326 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003647 name: 1-phenylethanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2." [UM-BBD_enzymeID:e0210] xref: EC:1.1.-.- xref: GO:0018449 xref: UM-BBD_enzymeID:e0210 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003648 name: myrtenol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal." [UM-BBD_enzymeID:e0444] xref: EC:1.1.-.- xref: GO:0018450 xref: UM-BBD_enzymeID:e0444 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003649 name: epoxide dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: ethene oxide (ethylene oxide) + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA." [UM-BBD_enzymeID:e0398] xref: EC:1.1.1.- xref: GO:0018451 xref: UM-BBD_enzymeID:e0398 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003650 name: 5-exo-hydroxycamphor dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane." [UM-BBD_enzymeID:e0301] xref: EC:1.1.1.- xref: GO:0018452 xref: UM-BBD_enzymeID:e0301 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003651 name: 2-hydroxytetrahydrofuran dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone." [UM-BBD_enzymeID:e0016] xref: EC:1.1.1.- xref: GO:0018453 xref: UM-BBD_enzymeID:e0016 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003652 name: acetoacetyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+." [EC:1.1.1.36] subset: gosubset_prok synonym: "(R)-3-hydroxyacyl-CoA dehydrogenase activity" EXACT [EC:1.1.1.36] synonym: "(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.36] synonym: "acetoacetyl coenzyme A reductase activity" EXACT [EC:1.1.1.36] synonym: "beta-ketoacyl-CoA reductase" BROAD [EC:1.1.1.36] synonym: "D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity" EXACT [EC:1.1.1.36] synonym: "D-3-hydroxyacyl-CoA reductase activity" EXACT [EC:1.1.1.36] synonym: "hydroxyacyl coenzyme-A dehydrogenase activity" EXACT [EC:1.1.1.36] synonym: "NADP-linked acetoacetyl CoA reductase activity" EXACT [EC:1.1.1.36] synonym: "NADPH:acetoacetyl-CoA reductase activity" EXACT [EC:1.1.1.36] synonym: "short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity" EXACT [EC:1.1.1.36] xref: EC:1.1.1.36 xref: GO:0018454 xref: MetaCyc:ACETOACETYL-COA-REDUCTASE-RXN xref: UM-BBD_enzymeID:e0005 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003653 name: alcohol dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+." [EC:1.1.1.71] synonym: "alcohol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.71] synonym: "aldehyde reductase (NADPH/NADH)" EXACT [EC:1.1.1.71] synonym: "retinal reductase activity" NARROW [EC:1.1.1.71] xref: EC:1.1.1.71 xref: GO:0018455 xref: MetaCyc:ALCOHOL-DEHYDROGENASE-(NAD(P)+)-RXN xref: UM-BBD_enzymeID:e0169 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003654 name: aryl-alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+." [EC:1.1.1.90] subset: gosubset_prok synonym: "aryl-alcohol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.90] synonym: "benzyl alcohol dehydrogenase activity" NARROW [] synonym: "coniferyl alcohol dehydrogenase" BROAD [EC:1.1.1.90] synonym: "p-hydroxybenzyl alcohol dehydrogenase activity" NARROW [EC:1.1.1.90] xref: EC:1.1.1.90 xref: GO:0018456 xref: MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0019 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003655 name: perillyl-alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: perillyl alcohol + NAD+ = perillyl aldehyde + NADH + H+." [EC:1.1.1.144] synonym: "perillyl alcohol dehydrogenase activity" EXACT [EC:1.1.1.144] synonym: "perillyl-alcohol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.144] xref: EC:1.1.1.144 xref: GO:0018457 xref: MetaCyc:PERILLYL-ALCOHOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0459 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003656 name: isopiperitenol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-trans-isopiperitenol + NAD+ = (-)-isopiperitenone + NADH + H+." [EC:1.1.1.223] synonym: "(-)-trans-isopiperitenol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.223] xref: EC:1.1.1.223 xref: GO:0018458 xref: MetaCyc:ISOPIPERITENOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0468 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003657 name: carveol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-trans-carveol + NADP+ = (-)-carvone + NADPH + H+." [EC:1.1.1.243] synonym: "(-)-trans-carveol dehydrogenase activity" EXACT [EC:1.1.1.243] synonym: "(-)-trans-carveol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.243] xref: EC:1.1.1.243 xref: GO:0018459 xref: MetaCyc:CARVEOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0446 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003658 name: cyclohexanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+." [EC:1.1.1.245] synonym: "cyclohexanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.245] xref: EC:1.1.1.245 xref: GO:0018460 xref: MetaCyc:CYCLOHEXANOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0165 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003659 name: fluoren-9-ol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+." [EC:1.1.1.256] synonym: "9-fluorenol dehydrogenase activity" EXACT [] synonym: "fluoren-9-ol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.256] xref: EC:1.1.1.256 xref: GO:0018461 xref: MetaCyc:9-FLUORENOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0292 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003660 name: 4-(hydroxymethyl)benzenesulfonate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + NADH + H+." [EC:1.1.1.257] synonym: "4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.257] synonym: "4-(hydroxymethyl)benzenesulphonate dehydrogenase activity" EXACT [] synonym: "4-sulfobenzyl alcohol dehydrogenase activity" EXACT [] xref: EC:1.1.1.257 xref: GO:0018462 xref: MetaCyc:1.1.1.257-RXN xref: UM-BBD_enzymeID:e0239 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003661 name: 6-hydroxyhexanoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + NADH + H+." [EC:1.1.1.258] synonym: "6-hydroxyhexanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.258] xref: EC:1.1.1.258 xref: GO:0018463 xref: MetaCyc:6-HYDROXYHEXANOATE-OXIDATION-RXN xref: UM-BBD_enzymeID:e0168 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003662 name: 3-hydroxypimeloyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxypimeloyl-CoA + NAD+ = 3-oxopimeloyl-CoA + NADH + H+." [EC:1.1.1.259] synonym: "3-hydroxypimeloyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.259] xref: EC:1.1.1.259 xref: GO:0018464 xref: MetaCyc:1.1.1.259-RXN xref: UM-BBD_enzymeID:e0181 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003663 name: vanillyl-alcohol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: vanillyl alcohol + O2 = vanillin + H2O2." [EC:1.1.3.38] synonym: "4-hydroxy-2-methoxybenzyl alcohol oxidase activity" EXACT [EC:1.1.3.38] synonym: "vanillyl alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.38] xref: EC:1.1.3.38 xref: GO:0018465 xref: MetaCyc:1.1.3.38-RXN xref: UM-BBD_enzymeID:e0404 is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0003664 name: limonene-1,2-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene." [UM-BBD_enzymeID:e0463] xref: EC:1.1.99.- xref: GO:0018466 xref: UM-BBD_enzymeID:e0463 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003665 name: formaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: formaldehyde + NAD+ + H2O = formate + NADH + H+. This enzyme does not need reduced glutathione." [EC:1.2.1.46] subset: gosubset_prok synonym: "formaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.46] synonym: "glutathione-independent formaldehyde dehydrogenase activity" EXACT [] xref: EC:1.2.1.46 xref: GO:0018467 xref: MetaCyc:FORMALDEHYDE-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0120 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003666 name: alcohol dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor." [EC:1.1.99.8] subset: gosubset_prok synonym: "alcohol:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.8] synonym: "alcohol:acceptor oxidoreductase activity" EXACT [EC:1.1.99.8] synonym: "MDH" RELATED [EC:1.1.99.8] synonym: "PQQ-dependent alcohol dehydrogenase activity" EXACT [] synonym: "primary alcohol dehydrogenase" BROAD [EC:1.1.99.8] synonym: "quinohemoprotein alcohol dehydrogenase activity" EXACT [EC:1.1.99.8] synonym: "quinoprotein alcohol dehydrogenase activity" EXACT [EC:1.1.99.8] synonym: "quinoprotein ethanol dehydrogenase activity" EXACT [EC:1.1.99.8] xref: EC:1.1.99.8 xref: GO:0018468 xref: MetaCyc:ALCOHOL-DEHYDROGENASE-(ACCEPTOR)-RXN xref: UM-BBD_enzymeID:e0004 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0003667 name: myrtenal dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid." [UM-BBD_enzymeID:e0448] xref: EC:1.2.-.- xref: GO:0018469 xref: UM-BBD_enzymeID:e0448 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003668 name: 4-hydroxybutaraldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate." [UM-BBD_enzymeID:e0018] xref: EC:1.2.-.- xref: GO:0018470 xref: UM-BBD_enzymeID:e0018 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003669 name: 4-chlorobenzaldehyde oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-." [UM-BBD_enzymeID:e0316] xref: EC:1.14.13.- xref: GO:0018471 xref: UM-BBD_enzymeID:e0316 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003670 name: 1-hydroxy-2-naphthaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate." [UM-BBD_enzymeID:e0328] xref: EC:1.2.1.- xref: GO:0018472 xref: UM-BBD_enzymeID:e0328 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003671 name: cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid." [UM-BBD_enzymeID:e0472] xref: EC:1.2.1.- xref: GO:0018473 xref: UM-BBD_enzymeID:e0472 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003672 name: 2-carboxybenzaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate." [UM-BBD_enzymeID:e0331] xref: EC:1.2.1.- xref: GO:0018474 xref: UM-BBD_enzymeID:e0331 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003673 name: trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid." [UM-BBD_enzymeID:e0474] xref: EC:1.2.1.- xref: GO:0018475 xref: UM-BBD_enzymeID:e0474 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003674 name: benzaldehyde dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+." [EC:1.2.1.7] synonym: "benzaldehyde:NADP+ oxidoreductase" EXACT [EC:1.2.1.7] synonym: "NADP-linked benzaldehyde dehydrogenase" EXACT [EC:1.2.1.7] xref: EC:1.2.1.7 xref: GO:0018477 xref: MetaCyc:BENZALDEHYDE-DEHYDROGENASE-(NADP+)-RXN xref: UM-BBD_enzymeID:e0079 is_a: CCO:F0004061 ! benzaldehyde dehydrogenase activity [Term] id: CCO:F0003675 name: malonate-semialdehyde dehydrogenase (acetylating) activity namespace: molecular_function def: "Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+." [EC:1.2.1.18] subset: gosubset_prok synonym: "3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)" EXACT [EC:1.2.1.18] synonym: "malonic semialdehyde oxidative decarboxylase activity" EXACT [] xref: EC:1.2.1.18 xref: GO:0018478 xref: MetaCyc:1.2.1.18-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003676 name: benzaldehyde dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+." [EC:1.2.1.28] subset: gosubset_prok synonym: "benzaldehyde (NAD) dehydrogenase activity" EXACT [EC:1.2.1.28] synonym: "benzaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.28] xref: EC:1.2.1.28 xref: GO:0018479 xref: MetaCyc:BENZALDEHYDE-DEHYDROGENASE-(NAD+)-RXN xref: UM-BBD_enzymeID:e0101 is_a: CCO:F0004061 ! benzaldehyde dehydrogenase activity [Term] id: CCO:F0003677 name: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+." [EC:1.2.1.60] subset: gosubset_prok synonym: "5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.60] synonym: "carboxymethylhydroxymuconic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.60] xref: EC:1.2.1.60 xref: GO:0018480 xref: MetaCyc:CHMS-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0280 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003678 name: 4-hydroxymuconic-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxymuconic semialdehyde + NAD+ + H2O = maleylacetate + NADH + H+." [EC:1.2.1.61] subset: gosubset_prok synonym: "4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.61] xref: EC:1.2.1.61 xref: GO:0018481 xref: MetaCyc:1.2.1.61-RXN xref: UM-BBD_enzymeID:e0204 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003679 name: 4-formylbenzenesulfonate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-formylbenzenesulfonate + NAD+ + H2O = 4-sulfobenzoate + NADH + H+." [EC:1.2.1.62] synonym: "4-formylbenzenesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.62] synonym: "4-formylbenzenesulphonate dehydrogenase activity" EXACT [] synonym: "toluene-sulfonate aldehyde dehydrogenase activity" EXACT [] xref: EC:1.2.1.62 xref: GO:0018482 xref: MetaCyc:1.2.1.62-RXN xref: UM-BBD_enzymeID:e0240 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003680 name: 6-oxohexanoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+." [EC:1.2.1.63] synonym: "6-oxohexanoate:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.63] xref: EC:1.2.1.63 xref: GO:0018483 xref: MetaCyc:6-OXOHEXANOATE-OXIDATION-RXN xref: UM-BBD_enzymeID:e0171 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003681 name: 4-hydroxybenzaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+." [EC:1.2.1.64] synonym: "3-hydroxybenzaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.64] synonym: "p-hydroxybenzaldehyde dehydrogenase activity" EXACT [EC:1.2.1.64] xref: EC:1.2.1.64 xref: GO:0018484 xref: MetaCyc:1.2.1.64-RXN xref: UM-BBD_enzymeID:e0226 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003682 name: salicylaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+." [EC:1.2.1.65] subset: gosubset_prok synonym: "salicylaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.65] xref: EC:1.2.1.65 xref: GO:0018485 xref: MetaCyc:1.2.1.65-RXN xref: UM-BBD_enzymeID:e0256 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003683 name: 2-butanone oxidase activity namespace: molecular_function def: "Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate." [UM-BBD_enzymeID:e0053] xref: EC:1.2.3.- xref: GO:0018486 xref: UM-BBD_enzymeID:e0053 is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0003684 name: vanillate O-demethylase (anaerobic) activity namespace: molecular_function def: "Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate." [UM-BBD_enzymeID:e0480] xref: EC:1.2.3.- xref: GO:0018487 xref: UM-BBD_enzymeID:e0480 is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor is_a: CCO:F0004997 ! demethylase activity [Term] id: CCO:F0003685 name: aryl-aldehyde oxidase activity namespace: molecular_function def: "Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + H2O2." [EC:1.2.3.9] synonym: "aryl-aldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.9] xref: EC:1.2.3.9 xref: GO:0018488 xref: MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN xref: UM-BBD_enzymeID:e0116 is_a: CCO:F0000509 ! aldehyde oxidase activity [Term] id: CCO:F0003686 name: vanillate monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: vanillate + O2 + NADH + H+ = 3,4-dihydroxybenzoate + NAD+ + H2O + formaldehyde." [EC:1.14.13.82] comment: Note that this was EC:1.2.3.12. subset: gosubset_prok synonym: "4-hydroxy-3-methoxybenzoate demethylase activity" EXACT [EC:1.14.13.82] synonym: "vanillate demethylase (aerobic) activity" EXACT [] synonym: "vanillate demethylase activity" EXACT [] synonym: "vanillate:oxygen oxidoreductase (demethylating)" EXACT [EC:1.14.13.82] xref: EC:1.14.13.82 xref: GO:0018489 xref: MetaCyc:RXN-2 xref: UM-BBD_enzymeID:e0117 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen is_a: CCO:F0004997 ! demethylase activity [Term] id: CCO:F0003687 name: 4-hydroxyphenylpyruvate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxyphenylpyruvate + 1/2 O2 = 4-hydroxyphenylacetate + CO2." [EC:1.2.3.13] synonym: "4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)" BROAD [EC:1.2.3.13] xref: EC:1.2.3.13 xref: GO:0018490 xref: MetaCyc:1.2.3.13-RXN xref: UM-BBD_enzymeID:e0244 is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0003688 name: 2-oxobutyrate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.2] synonym: "2-ketobutyrate synthase activity" EXACT [EC:1.2.7.2] synonym: "2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)" EXACT [EC:1.2.7.2] synonym: "2-oxobutyrate-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.2] synonym: "alpha-ketobutyrate synthase activity" EXACT [EC:1.2.7.2] synonym: "alpha-ketobutyrate-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.2] xref: EC:1.2.7.2 xref: GO:0018491 xref: MetaCyc:2-OXOBUTYRATE-SYNTHASE-RXN xref: UM-BBD_enzymeID:e0275 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003689 name: carbon-monoxide dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor." [EC:1.2.99.2] subset: gosubset_prok synonym: "anaerobic carbon monoxide dehydrogenase activity" EXACT [EC:1.2.99.2] synonym: "carbon monoxide dehydrogenase activity" BROAD [] synonym: "carbon-monoxide:acceptor oxidoreductase activity" EXACT [EC:1.2.99.2] xref: EC:1.2.99.2 xref: GO:0018492 xref: MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0415 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003690 name: formylmethanofuran dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor." [EC:1.2.99.5] subset: gosubset_prok synonym: "formylmethanofuran:(acceptor) oxidoreductase activity" EXACT [EC:1.2.99.5] synonym: "formylmethanofuran:acceptor oxidoreductase activity" EXACT [EC:1.2.99.5] xref: EC:1.2.99.5 xref: GO:0018493 xref: MetaCyc:FORMYLMETHANOFURAN-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0121 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0003691 name: carvone reductase activity namespace: molecular_function def: "Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone." [UM-BBD_enzymeID:e0473] xref: EC:1.3.-.- xref: GO:0018494 xref: UM-BBD_enzymeID:e0473 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003692 name: 2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA." [UM-BBD_enzymeID:e0177] xref: EC:1.3.-.- xref: GO:0018495 xref: UM-BBD_enzymeID:e0177 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003693 name: 2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA." [UM-BBD_enzymeID:e0186] xref: EC:1.3.-.- xref: GO:0018496 xref: UM-BBD_enzymeID:e0186 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003694 name: 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS." [UM-BBD_enzymeID:e0352] synonym: "DDMS dehydrogenase activity" EXACT [] xref: EC:1.3.-.- xref: GO:0018497 xref: UM-BBD_enzymeID:e0352 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003695 name: 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate." [UM-BBD_enzymeID:e0308] xref: EC:1.3.1.- xref: GO:0018498 xref: UM-BBD_enzymeID:e0308 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003696 name: cis-2,3-dihydrodiol DDT dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT." [UM-BBD_enzymeID:e0320] xref: EC:1.3.1.- xref: GO:0018499 xref: UM-BBD_enzymeID:e0320 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003697 name: trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene." [UM-BBD_enzymeID:e0381] xref: EC:1.3.1.- xref: GO:0018500 xref: UM-BBD_enzymeID:e0381 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003698 name: cis-chlorobenzene dihydrodiol dehydrogenase activity namespace: molecular_function xref: EC:1.3.1.- xref: GO:0018501 xref: UM-BBD_enzymeID:e0411 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003699 name: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone." [UM-BBD_enzymeID:e0362] xref: EC:1.3.1.- xref: GO:0018502 xref: UM-BBD_enzymeID:e0362 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003700 name: trans-1,2-dihydrodiolphenanthrene dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene." [UM-BBD_enzymeID:e0380] xref: EC:1.3.1.- xref: GO:0018503 xref: UM-BBD_enzymeID:e0380 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003701 name: cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+." [EC:1.3.1.19] subset: gosubset_prok synonym: "cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.19] synonym: "cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase activity" EXACT [EC:1.3.1.19] synonym: "cis-benzene glycol dehydrogenase activity" EXACT [EC:1.3.1.19] xref: EC:1.3.1.19 xref: GO:0018504 xref: MetaCyc:1.3.1.19-RXN xref: UM-BBD_enzymeID:e0060 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003702 name: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+." [EC:1.3.1.29] synonym: "(+)-cis-naphthalene dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.29] synonym: "1,2-dihydroxy-1,2-dihydroxynaphthalene dehydrogenase activity" EXACT [] synonym: "cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase activity" EXACT [EC:1.3.1.29] synonym: "cis-dihydrodiol naphthalene dehydrogenase activity" EXACT [EC:1.3.1.29] synonym: "cis-naphthalene dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.29] synonym: "naphthalene dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.29] xref: EC:1.3.1.29 xref: GO:0018505 xref: MetaCyc:1.3.1.29-RXN xref: UM-BBD_enzymeID:e0122 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003703 name: maleylacetate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+." [EC:1.3.1.32] subset: gosubset_prok synonym: "3-oxoadipate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.32] synonym: "maleolylacetate reductase activity" EXACT [EC:1.3.1.32] xref: EC:1.3.1.32 xref: GO:0018506 xref: MetaCyc:MALEYLACETATE-REDUCTASE-RXN xref: UM-BBD_enzymeID:e0063 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003704 name: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-cis-3,4-dihydrophenanthrene-3,4-diol + NAD+ = phenanthrene-3,4-diol + NADH + H+." [EC:1.3.1.49] synonym: "(+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase activity" EXACT [EC:1.3.1.49] synonym: "cis-3,4-dihydroxy-3,4-dihydrophenanthrene dehydrogenase activity" EXACT [] xref: EC:1.3.1.49 xref: GO:0018507 xref: MetaCyc:1.3.1.49-RXN xref: UM-BBD_enzymeID:e0322 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003705 name: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+." [MetaCyc:BENZOATE-CIS-DIOL-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "benzoate cis-diol dehydrogenase activity" EXACT [] xref: GO:0018508 xref: MetaCyc:BENZOATE-CIS-DIOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0219 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003706 name: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+." [EC:1.3.1.56] subset: gosubset_prok synonym: "2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase activity" EXACT [] synonym: "biphenyl-2,3-dihydro-2,3-diol dehydrogenase activity" EXACT [EC:1.3.1.56] synonym: "cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.56] xref: EC:1.3.1.56 xref: GO:0018509 xref: MetaCyc:1.3.1.56-RXN xref: UM-BBD_enzymeID:e0134 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003707 name: phloroglucinol reductase activity namespace: molecular_function def: "Catalysis of the reaction: dihydrophloroglucinol + NADP+ = phloroglucinol + NADPH + H+." [EC:1.3.1.57] subset: gosubset_prok synonym: "dihydrophloroglucinol:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.57] xref: EC:1.3.1.57 xref: GO:0018510 xref: MetaCyc:R5-RXN xref: UM-BBD_enzymeID:e0010 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003708 name: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD+ = 2,3-dihydroxy-p-cumate + NADH + H+." [EC:1.3.1.58] subset: gosubset_prok synonym: "cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.58] xref: EC:1.3.1.58 xref: GO:0018511 xref: MetaCyc:RXN-665 xref: UM-BBD_enzymeID:e0284 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003709 name: dibenzothiophene dihydrodiol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD+ = 1,2-dihydroxydibenzothiophene + NADH + H+." [EC:1.3.1.60] subset: gosubset_prok synonym: "cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.60] xref: EC:1.3.1.60 xref: GO:0018513 xref: MetaCyc:1.3.1.60-RXN xref: UM-BBD_enzymeID:e0161 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003710 name: terephthalate 1,2-cis-dihydrodiol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate + NAD+ = 3,4-dihydroxybenzoate + CO2 + NADH + H+." [EC:1.3.1.61] synonym: "cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.61] xref: EC:1.3.1.61 xref: GO:0018514 xref: MetaCyc:1.3.1.61-RXN xref: UM-BBD_enzymeID:e0108 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003711 name: pimeloyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+." [EC:1.3.1.62] subset: gosubset_prok synonym: "pimeloyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.62] xref: EC:1.3.1.62 xref: GO:0018515 xref: MetaCyc:1.3.1.62-RXN xref: UM-BBD_enzymeID:e0179 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003712 name: 2,4-dichlorobenzoyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-chlorobenzoyl-CoA + NADP+ + HCl = 2,4-dichlorobenzoyl-CoA + NADPH + H+." [EC:1.3.1.63] synonym: "4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)" EXACT [EC:1.3.1.63] xref: EC:1.3.1.63 xref: GO:0018516 xref: MetaCyc:1.3.1.63-RXN xref: UM-BBD_enzymeID:e0111 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003713 name: phthalate 4,5-cis-dihydrodiol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + NADH + H+." [EC:1.3.1.64] synonym: "cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.64] xref: EC:1.3.1.64 xref: GO:0018517 xref: MetaCyc:1.3.1.64-RXN xref: UM-BBD_enzymeID:e0105 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003714 name: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+ = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H+." [EC:1.3.1.65] synonym: "5,6-dihydrodiol-3-methyl-2-oxo-1,2-dihydroquinoline dehydrogenase" RELATED [] synonym: "5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.65] xref: EC:1.3.1.65 xref: GO:0018518 xref: MetaCyc:RXN-643 xref: UM-BBD_enzymeID:e0047 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003715 name: cis-dihydroethylcatechol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD+ = 3-ethylcatechol + NADH + H+." [EC:1.3.1.66] synonym: "cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.66] synonym: "cis-ethylbenzene glycol dehydrogenase activity" EXACT [] xref: EC:1.3.1.66 xref: GO:0018519 xref: MetaCyc:1.3.1.66-RXN xref: UM-BBD_enzymeID:e0218 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003716 name: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2." [EC:1.3.1.67] synonym: "4-methylcyclohexa-3,5-diene-1,2-cis-diol-1-carboxylic acid dehydrogenase activity" EXACT [] synonym: "cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.67] xref: EC:1.3.1.67 xref: GO:0018520 xref: MetaCyc:1.3.1.67-RXN xref: UM-BBD_enzymeID:e0173 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003717 name: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ = 3-methylcatechol + NADH + H+ + CO2." [EC:1.3.1.68] synonym: "1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.68] xref: EC:1.3.1.68 xref: GO:0018521 xref: MetaCyc:1.3.1.68-RXN xref: UM-BBD_enzymeID:e0194 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003718 name: benzoyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: benzoyl-CoA + donor-H2 + 2 ATP = cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP + 2 phosphate." [EC:1.3.99.15] subset: gosubset_prok synonym: "benzoyl-CoA reductase (dearomatizing) activity" EXACT [EC:1.3.99.15] synonym: "cyclohexa-1,5-diene-1-carbonyl-CoA:acceptor oxidoreductase (aromatizing, ATP-forming)" EXACT [EC:1.3.99.15] xref: EC:1.3.99.15 xref: GO:0018522 xref: MetaCyc:1.3.99.15-RXN xref: UM-BBD_enzymeID:e0176 is_a: CCO:F0004055 ! acyl-CoA reductase activity [Term] id: CCO:F0003719 name: quinoline 2-oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor." [EC:1.3.99.17] subset: gosubset_prok synonym: "quinoline:acceptor 2-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.17] xref: EC:1.3.99.17 xref: GO:0018523 xref: MetaCyc:1.3.99.17-RXN xref: UM-BBD_enzymeID:e0041 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0003720 name: acetophenone carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate." [UM-BBD_enzymeID:e0211] xref: EC:6.4.1.- xref: GO:0018524 xref: GO:0018797 xref: UM-BBD_enzymeID:e0211 is_a: CCO:F0003443 ! ligase activity, forming carbon-carbon bonds [Term] id: CCO:F0003721 name: 4-hydroxybenzoyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybenzoyl-CoA + acceptor = benzoyl-CoA + reduced acceptor." [EC:1.3.99.20] subset: gosubset_prok synonym: "4-hydroxybenzoyl-CoA reductase (dehydroxylating) activity" EXACT [EC:1.3.99.20] synonym: "4-hydroxybenzoyl-CoA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.99.20] synonym: "4-hydroxybenzoyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.3.99.20] xref: EC:1.3.99.20 xref: GO:0018525 xref: MetaCyc:1.3.99.20-RXN xref: UM-BBD_enzymeID:e0159 is_a: CCO:F0004055 ! acyl-CoA reductase activity [Term] id: CCO:F0003722 name: 2-aminobenzoyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA." [UM-BBD_enzymeID:e0263] xref: EC:1.4.-.- xref: GO:0018526 xref: UM-BBD_enzymeID:e0263 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0003723 name: cyclohexylamine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + H2O2." [EC:1.4.3.12] synonym: "cyclohexylamine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.12] xref: EC:1.4.3.12 xref: GO:0018527 xref: MetaCyc:CYCLOHEXYLAMINE-OXIDASE-RXN xref: UM-BBD_enzymeID:e0477 is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0003724 name: iminodiacetate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine." [UM-BBD_enzymeID:e0390] xref: EC:1.5.-.- xref: GO:0018528 xref: UM-BBD_enzymeID:e0390 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003725 name: nitrilotriacetate monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate." [UM-BBD_enzymeID:e0388] xref: EC:1.5.1.- xref: GO:0018529 xref: UM-BBD_enzymeID:e0388 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0003728 name: F433-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin." [UM-BBD_enzymeID:e0265] synonym: "F433-independent methylene-H4MPT dehydrogenase activity" EXACT [] xref: EC:1.5.99.- xref: GO:0018532 xref: UM-BBD_enzymeID:e0265 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003729 name: nitrilotriacetate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate." [UM-BBD_enzymeID:e0389] xref: EC:1.5.99.- xref: GO:0018534 xref: UM-BBD_enzymeID:e0389 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003730 name: nicotine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor." [EC:1.5.99.4] subset: gosubset_prok synonym: "D-nicotine oxidase activity" EXACT [EC:1.5.99.4] synonym: "nicotine oxidase activity" EXACT [EC:1.5.99.4] synonym: "nicotine:(acceptor) 6-oxidoreductase (hydroxylating)" EXACT [EC:1.5.99.4] synonym: "nicotine:acceptor 6-oxidoreductase (hydroxylating)" EXACT [EC:1.5.99.4] xref: EC:1.5.99.4 xref: GO:0018535 xref: MetaCyc:NICOTINE-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0337 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003731 name: coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity namespace: molecular_function def: "Catalysis of the reaction: N5,N10-methylenetetrahydromethanopterin + reduced coenzyme F420 = 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme F420." [EC:1.5.99.11] subset: gosubset_prok synonym: "5,10-methylenetetrahydromethanopterin cyclohydrolase activity" EXACT [EC:1.5.99.11] synonym: "5,10-methylenetetrahydromethanopterin reductase activity" EXACT [EC:1.5.99.11] synonym: "5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.99.11] synonym: "coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase activity" EXACT [EC:1.5.99.11] synonym: "methylene-H(4)MPT reductase activity" EXACT [EC:1.5.99.11] synonym: "methylene-H4MPT reductase activity" EXACT [EC:1.5.99.11] synonym: "methylenetetrahydromethanopterin reductase activity" EXACT [] synonym: "N(5),N(10)-methylenetetrahydromethanopterin reductase activity" EXACT [EC:1.5.99.11] synonym: "N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.99.11] synonym: "N5,N10-methylenetetrahydromethanopterin reductase activity" EXACT [EC:1.5.99.11] synonym: "N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.99.11] xref: EC:1.5.99.11 xref: GO:0018537 xref: MetaCyc:METHELENE-THMPT-OXI-RXN xref: UM-BBD_enzymeID:e0266 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0003732 name: epoxide carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ring opening and carboxylation of an epoxide; the reaction requires CO2 as a cosubstrate and forms a beta-keto acid as a products. An example of such a reaction is: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+." [PMID:9555888] xref: EC:1.6.-.- xref: GO:0018538 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0003733 name: p-benzoquinone reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H+ + p-benzoquinone = NADP+ + hydroquinone." [EC:1.6.5.6] synonym: "NADPH:p-benzoquinone oxidoreductase activity" EXACT [EC:1.6.5.6] xref: EC:1.6.5.6 xref: GO:0018541 xref: MetaCyc:1.6.5.6-RXN xref: UM-BBD_enzymeID:e0422 is_a: CCO:F0003253 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [Term] id: CCO:F0003734 name: 2,3-dihydroxy DDT 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate." [UM-BBD_enzymeID:e0315] xref: EC:1.13.11.- xref: GO:0018542 xref: UM-BBD_enzymeID:e0315 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003735 name: 4-amino-2-nitroso-6-nitrotoluene reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene." [UM-BBD_enzymeID:e0365] xref: EC:1.6.6.- xref: GO:0018543 xref: UM-BBD_enzymeID:e0365 is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0003736 name: 4-carboxy-4'-sulfoazobenzene reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate." [UM-BBD_enzymeID:e0391] synonym: "4-carboxy-4'-sulphoazobenzene reductase activity" EXACT [] xref: EC:1.6.6.- xref: GO:0018544 xref: UM-BBD_enzymeID:e0391 is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0003737 name: NAD(P)H nitroreductase activity namespace: molecular_function xref: EC:1.6.6.- xref: GO:0018545 xref: UM-BBD_enzymeID:e0346 is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0003738 name: nitrobenzene nitroreductase activity namespace: molecular_function xref: EC:1.6.6.- xref: GO:0018546 xref: UM-BBD_enzymeID:e0245 is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0003739 name: nitroglycerin reductase activity namespace: molecular_function def: "Catalysis of the removal of one or more nitrite (NO2(-)) groups from nitroglycerin or a derivative." [UM-BBD_enzymeID:e0038] synonym: "NG reductase activity" EXACT [] xref: EC:1.7.3.- xref: GO:0018547 xref: UM-BBD_enzymeID:e0038 is_a: CCO:F0003258 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor [Term] id: CCO:F0003740 name: pentaerythritol tetranitrate reductase activity namespace: molecular_function def: "Catalysis of the reaction: pentaerythritol tri(or tetra)nitrate + NADPH = NADP+ + NO3- (nitrate) + pentaerythritol di(or tri)nitrate." [UM-BBD_enzymeID:e0035] xref: EC:1.7.99.- xref: GO:0018548 xref: UM-BBD_enzymeID:e0035 is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0003741 name: methanethiol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + H2O2." [EC:1.8.3.4] synonym: "(MM)-oxidase activity" EXACT [EC:1.8.3.4] synonym: "methanethiol:oxygen oxidoreductase activity" EXACT [EC:1.8.3.4] synonym: "methyl mercaptan oxidase activity" EXACT [EC:1.8.3.4] synonym: "methylmercaptan oxidase activity" EXACT [EC:1.8.3.4] synonym: "MT-oxidase activity" EXACT [EC:1.8.3.4] xref: EC:1.8.3.4 xref: GO:0018549 xref: MetaCyc:METHANETHIOL-OXIDASE-RXN xref: UM-BBD_enzymeID:e0153 is_a: CCO:F0003263 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor [Term] id: CCO:F0003742 name: tetrachloro-p-hyrodoquinone reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: organohalide + 2 GSH = GSSG + HCl + RH. Substrates are 2,3,5,6-tetrachlorohydroquinone (TeCH) (forms 2,3,6-trichlorohydroquinone (TrCH)) and 2,3,6-trichlorohydroquinone (TrCH) (forms 2,6-dichlorohydroquinone (DiCH))." [UM-BBD_enzymeID:e0251] xref: EC:1.8.99.- xref: GO:0018550 xref: UM-BBD_enzymeID:e0251 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003743 name: hydrogensulfite reductase activity namespace: molecular_function def: "Catalysis of the reaction: O3S-S-SO3(2-) + acceptor + 2 H2O + OH- = 3 HSO3(-) + reduced acceptor." [EC:1.8.99.3] subset: gosubset_prok synonym: "bisulfite reductase activity" EXACT [EC:1.8.99.3] synonym: "desulfofuscidin activity" NARROW [EC:1.8.99.3] synonym: "desulforubidin activity" NARROW [EC:1.8.99.3] synonym: "desulfoviridin activity" NARROW [EC:1.8.99.3] synonym: "dissimilatory sulfite reductase activity" EXACT [] synonym: "dissimilatory-type sulfite reductase activity" EXACT [EC:1.8.99.3] synonym: "hydrogensulphite reductase activity" EXACT [] synonym: "trithionate:(acceptor) oxidoreductase activity" EXACT [EC:1.8.99.3] synonym: "trithionate:acceptor oxidoreductase activity" EXACT [EC:1.8.99.3] xref: EC:1.8.99.3 xref: GO:0018551 xref: MetaCyc:HYDROGENSULFITE-REDUCTASE-RXN xref: UM-BBD_enzymeID:e0416 is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0003744 name: methyl-coenzyme-M reductase activity namespace: molecular_function def: "Catalysis of the reaction: methyl-coenzyme-M + HTP = CoM-S-S-HTP + methane." [UM-BBD_enzymeID:e0267] xref: EC:1.12.99.- xref: GO:0018552 xref: UM-BBD_enzymeID:e0267 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0003745 name: 3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate." [UM-BBD_enzymeID:e0309] xref: EC:1.13.-.- xref: GO:0018553 xref: UM-BBD_enzymeID:e0309 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is_a: CCO:F0008070 ! dioxygenase activity [Term] id: CCO:F0003746 name: 1,2-dihydroxynaphthalene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached." [UM-BBD_enzymeID:e0255] xref: EC:1.13.-.- xref: GO:0018554 xref: UM-BBD_enzymeID:e0255 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is_a: CCO:F0008070 ! dioxygenase activity [Term] id: CCO:F0003747 name: phenanthrene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ = cis-3,4-dihydroxy-3,4-dihydrophenanthrene." [UM-BBD_enzymeID:e0321] xref: EC:1.13.11.- xref: GO:0018555 xref: UM-BBD_enzymeID:e0321 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003748 name: 2,2',3-trihydroxybiphenyl dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate)." [UM-BBD_enzymeID:e0032] xref: EC:1.13.11.- xref: GO:0018556 xref: UM-BBD_enzymeID:e0032 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003749 name: 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid." [UM-BBD_enzymeID:e0295] xref: EC:1.13.11.- xref: GO:0018557 xref: UM-BBD_enzymeID:e0295 is_a: CCO:F0004063 ! dihydroxyfluorene dioxygenase activity [Term] id: CCO:F0003750 name: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon." [UM-BBD_enzymeID:e0044] xref: EC:1.13.11.- xref: GO:0018558 xref: UM-BBD_enzymeID:e0044 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003751 name: 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate." [UM-BBD_enzymeID:e0313] synonym: "1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity" EXACT [] xref: EC:1.13.11.- xref: GO:0018559 xref: UM-BBD_enzymeID:e0313 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003752 name: protocatechuate 3,4-dioxygenase type II activity namespace: molecular_function def: "Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate." [UM-BBD_enzymeID:e0385] xref: EC:1.13.11.- xref: GO:0018560 xref: UM-BBD_enzymeID:e0385 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003753 name: 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate." [UM-BBD_enzymeID:e0324] xref: EC:1.13.11.- xref: GO:0018561 xref: UM-BBD_enzymeID:e0324 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003754 name: 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid." [UM-BBD_enzymeID:e0294] xref: EC:1.13.11.- xref: GO:0018562 xref: UM-BBD_enzymeID:e0294 is_a: CCO:F0004063 ! dihydroxyfluorene dioxygenase activity [Term] id: CCO:F0003755 name: 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate." [UM-BBD_enzymeID:e0220] xref: EC:1.13.11.- xref: GO:0018563 xref: UM-BBD_enzymeID:e0220 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003756 name: carbazole 1,9a-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol." [UM-BBD_enzymeID:e0323] xref: EC:1.13.11.- xref: GO:0018564 xref: UM-BBD_enzymeID:e0323 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003757 name: dihydroxydibenzothiophene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate." [UM-BBD_enzymeID:e0162] xref: EC:1.13.11.- xref: GO:0018565 xref: UM-BBD_enzymeID:e0162 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003758 name: 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate." [UM-BBD_enzymeID:e0250] synonym: "1,2-dihydroxynaphthalene-6-sulphonate 1,8a-dioxygenase activity" EXACT [] xref: EC:1.13.11.- xref: GO:0018566 xref: UM-BBD_enzymeID:e0250 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003759 name: styrene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol." [UM-BBD_enzymeID:e0200] xref: EC:1.13.11.- xref: GO:0018567 xref: UM-BBD_enzymeID:e0200 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003760 name: 3,4-dihydroxyphenanthrene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate." [UM-BBD_enzymeID:e0345] xref: EC:1.13.11.- xref: GO:0018568 xref: UM-BBD_enzymeID:e0345 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003761 name: hydroquinone 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde." [UM-BBD_enzymeID:e0203] xref: EC:1.13.11.- xref: GO:0018569 xref: UM-BBD_enzymeID:e0203 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003762 name: p-cumate 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate." [UM-BBD_enzymeID:e0270] xref: EC:1.13.11.- xref: GO:0018570 xref: UM-BBD_enzymeID:e0270 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003763 name: 2,3-dihydroxy-p-cumate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate." [MetaCyc:RXN-666, UM-BBD_enzymeID:e0285] subset: gosubset_prok synonym: "2,3-dihydroxy-p-cumate 3,4-dioxygenase" EXACT [] synonym: "2,3-dihydroxy-p-cumate-3,4-dioxygenase" EXACT [] xref: EC:1.13.11.- xref: GO:0018571 xref: MetaCyc:RXN-666 xref: UM-BBD_enzymeID:e0285 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003764 name: 3,5-dichlorocatechol 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H + 2,4-dichloro-cis,cis-muconate." [UM-BBD_enzymeID:e0231] xref: EC:1.13.11.- xref: GO:0018572 xref: UM-BBD_enzymeID:e0231 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003765 name: 2-aminophenol 1,6-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde." [UM-BBD_enzymeID:e0247] xref: EC:1.13.11.- xref: GO:0018573 xref: UM-BBD_enzymeID:e0247 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003766 name: 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate." [UM-BBD_enzymeID:e0422] xref: EC:1.13.11.- xref: GO:0018574 xref: UM-BBD_enzymeID:e0422 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003767 name: chlorocatechol 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate." [UM-BBD_enzymeID:e0419] xref: EC:1.13.11.- xref: GO:0018575 xref: UM-BBD_enzymeID:e0419 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003768 name: catechol 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: catechol + O2 = cis,cis-muconate." [EC:1.13.11.1] subset: gosubset_prok synonym: "1,2-pyrocatechase activity" EXACT [EC:1.13.11.1] synonym: "catechase activity" RELATED [EC:1.13.11.1] synonym: "catechol 1,2-oxygenase activity" EXACT [EC:1.13.11.1] synonym: "catechol-oxygen 1,2-oxidoreductase activity" EXACT [EC:1.13.11.1] synonym: "catechol:oxygen 1,2-oxidoreductase activity" EXACT [EC:1.13.11.1] synonym: "CD I" RELATED [EC:1.13.11.1] synonym: "CD II" RELATED [EC:1.13.11.1] synonym: "pyrocatechase activity" RELATED [EC:1.13.11.1] synonym: "pyrocatechol 1,2-dioxygenase activity" EXACT [EC:1.13.11.1] xref: EC:1.13.11.1 xref: GO:0018576 xref: MetaCyc:CATECHOL-1 xref: UM-BBD_enzymeID:e0064 is_a: CCO:F0004060 ! catechol dioxygenase activity [Term] id: CCO:F0003769 name: catechol 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde." [EC:1.13.11.2] subset: gosubset_prok synonym: "2,3-pyrocatechase activity" EXACT [EC:1.13.11.2] synonym: "catechol 2,3-oxygenase" EXACT [EC:1.13.11.2] synonym: "catechol oxygenase" EXACT [EC:1.13.11.2] synonym: "catechol:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.2] synonym: "cato2ase activity" RELATED [EC:1.13.11.2] synonym: "metapyrocatechase activity" RELATED [EC:1.13.11.2] synonym: "pyrocatechol 2,3-dioxygenase" EXACT [EC:1.13.11.2] xref: EC:1.13.11.2 xref: GO:0018577 xref: MetaCyc:CATECHOL-2 xref: UM-BBD_enzymeID:e0156 is_a: CCO:F0004060 ! catechol dioxygenase activity [Term] id: CCO:F0003770 name: protocatechuate 3,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate." [EC:1.13.11.3] subset: gosubset_prok synonym: "protocatechuate oxygenase activity" BROAD [EC:1.13.11.3] synonym: "protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.3] synonym: "protocatechuic 3,4-dioxygenase activity" EXACT [EC:1.13.11.3] synonym: "protocatechuic 3,4-oxygenase activity" EXACT [EC:1.13.11.3] synonym: "protocatechuic acid oxidase activity" EXACT [EC:1.13.11.3] xref: EC:1.13.11.3 xref: GO:0018578 xref: MetaCyc:PROTOCATECHUATE-3 xref: UM-BBD_enzymeID:e0114 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003771 name: protocatechuate 4,5-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde." [EC:1.13.11.8] subset: gosubset_prok synonym: "protocatechuate 4,5-oxygenase activity" EXACT [EC:1.13.11.8] synonym: "protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.8] synonym: "protocatechuic 4,5-dioxygenase activity" EXACT [EC:1.13.11.8] synonym: "protocatechuic 4,5-oxygenase activity" EXACT [EC:1.13.11.8] xref: EC:1.13.11.8 xref: GO:0018579 xref: MetaCyc:PROTOCATECHUATE-4 xref: UM-BBD_enzymeID:e0115 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003772 name: 2-nitropropane dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 2-nitropropane + O2 = 2 acetone + 2 NO2(-) (nitrite)." [EC:1.13.11.32] subset: gosubset_prok synonym: "2-nitropropane:oxygen 2-oxidoreductase activity" EXACT [EC:1.13.11.32] synonym: "2-NPD activity" EXACT [EC:1.13.11.32] synonym: "nitroalkane oxidase activity" EXACT [EC:1.13.11.32] xref: EC:1.13.11.32 xref: GO:0018580 xref: MetaCyc:2-NITROPROPANE-DIOXYGENASE-RXN xref: UM-BBD_enzymeID:e0387 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003773 name: hydroxyquinol 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate." [EC:1.13.11.37] subset: gosubset_prok synonym: "benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.37] synonym: "hydroxyquinol dioxygenase activity" EXACT [EC:1.13.11.37] xref: EC:1.13.11.37 xref: GO:0018581 xref: MetaCyc:HYDROXYQUINOL-1 xref: UM-BBD_enzymeID:e0207 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003774 name: 1-hydroxy-2-naphthoate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate." [EC:1.13.11.38] synonym: "1-hydroxy-2-naphthoate dioxygenase activity" EXACT [] synonym: "1-hydroxy-2-naphthoate-degrading enzyme activity" NARROW [EC:1.13.11.38] synonym: "1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.38] synonym: "1-hydroxy-2-naphthoic acid dioxygenase activity" EXACT [EC:1.13.11.38] xref: EC:1.13.11.38 xref: GO:0018582 xref: MetaCyc:1.13.11.38-RXN xref: UM-BBD_enzymeID:e0329 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003775 name: biphenyl-2,3-diol 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O." [EC:1.13.11.39] subset: gosubset_prok synonym: "2,3-dihydroxybiphenyl 1,2-dioxygenase activity" BROAD [] synonym: "2,3-dihydroxybiphenyl dioxygenase activity" BROAD [EC:1.13.11.39] synonym: "biphenyl-2,3-diol dioxygenase activity" EXACT [EC:1.13.11.39] synonym: "biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.39] xref: EC:1.13.11.39 xref: GO:0018583 xref: MetaCyc:BIPHENYL-2 xref: UM-BBD_enzymeID:e0127 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0003776 name: 2,4,5-trichlorophenoxyacetic acid oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol." [UM-BBD_enzymeID:e0276] xref: EC:1.13.99.- xref: GO:0018584 xref: UM-BBD_enzymeID:e0276 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Term] id: CCO:F0003777 name: fluorene oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol." [UM-BBD_enzymeID:e0291] xref: EC:1.14.-.- xref: GO:0018585 xref: UM-BBD_enzymeID:e0291 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003778 name: mono-butyltin dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: butyltin (MBT) + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin." [UM-BBD_enzymeID:e0407] synonym: "MBT dioxygenase activity" EXACT [] xref: EC:1.14.-.- xref: GO:0018586 xref: UM-BBD_enzymeID:e0407 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003780 name: tri-n-butyltin dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: tri-n-butyltin (TBT) + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin." [UM-BBD_enzymeID:e0349] synonym: "TBT dioxygenase activity" EXACT [] xref: EC:1.14.-.- xref: GO:0018588 xref: UM-BBD_enzymeID:e0349 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003781 name: di-n-butyltin dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: dibutyltin (DBT) + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin." [UM-BBD_enzymeID:e0360] synonym: "DBT dioxygenase activity" EXACT [] xref: EC:1.14.-.- xref: GO:0018589 xref: UM-BBD_enzymeID:e0360 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003782 name: methylsilanetriol hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol." [UM-BBD_enzymeID:e0343] xref: EC:1.14.-.- xref: GO:0018590 xref: UM-BBD_enzymeID:e0343 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003783 name: methyl tertiary butyl ether 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde." [UM-BBD_reactionID:r1023] synonym: "MTBE 3-monooxygenase activity" EXACT [] xref: EC:1.14.-.- xref: GO:0018591 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003784 name: 4-nitrocatechol 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + NO2(-) (nitrite) + 1,2,4-benzenetriol." [UM-BBD_enzymeID:e0206] xref: EC:1.14.-.- xref: GO:0018592 xref: UM-BBD_enzymeID:e0206 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003785 name: 4-chlorophenoxyacetate monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol." [UM-BBD_enzymeID:e0234] xref: EC:1.14.-.- xref: GO:0018593 xref: UM-BBD_enzymeID:e0234 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003786 name: tert-butyl alcohol 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: tert-butyl alcohol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol." [UM-BBD_reactionID:r0615] xref: EC:1.14.-.- xref: GO:0018594 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003787 name: alpha-pinene monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol." [UM-BBD_enzymeID:e0475] xref: EC:1.14.-.- xref: GO:0018595 xref: UM-BBD_enzymeID:e0475 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003788 name: dimethylsilanediol hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol." [UM-BBD_enzymeID:e0288] synonym: "DMSD hydroxylase activity" EXACT [] xref: EC:1.14.-.- xref: GO:0018596 xref: UM-BBD_enzymeID:e0288 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003789 name: ammonia monooxygenase activity namespace: molecular_function subset: gosubset_prok xref: EC:1.14.-.- xref: GO:0018597 xref: UM-BBD_enzymeID:e0061 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003790 name: hydroxymethylsilanetriol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol." [UM-BBD_enzymeID:e0348] xref: EC:1.14.-.- xref: GO:0018598 xref: UM-BBD_enzymeID:e0348 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003791 name: 2-hydroxyisobutyrate 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate." [UM-BBD_enzymeID:e0410] xref: EC:1.14.-.- xref: GO:0018599 xref: UM-BBD_enzymeID:e0410 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003792 name: alpha-pinene dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol." [UM-BBD_enzymeID:e0441] xref: EC:1.14.-.- xref: GO:0018600 xref: UM-BBD_enzymeID:e0441 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003793 name: 4-nitrophenol 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: p-nitrophenol + O2 + NADH + H+ = H2O + 4-nitrocatechol + NAD+." [EC:1.14.13.29, UM-BBD_enzymeID:e0205] synonym: "4-nitrophenol hydroxylase activity" EXACT [EC:1.14.13.29] synonym: "4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.29] synonym: "4-nitrophenol-2-hydroxylase activity" EXACT [EC:1.14.13.29] xref: EC:1.14.13.29 xref: GO:0018601 xref: MetaCyc:4-NITROPHENOL-2-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0205 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003794 name: 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid = glyoxylate + 2,4-dichlorophenol." [UM-BBD_enzymeID:e0230] xref: EC:1.14.11.- xref: GO:0018602 xref: UM-BBD_enzymeID:e0230 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0003795 name: nitrobenzene 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + NO2(-) (nitrite) + catechol." [UM-BBD_enzymeID:e0248] xref: EC:1.14.12.- xref: GO:0018603 xref: UM-BBD_enzymeID:e0248 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003796 name: 4-aminobenzoate 3,4-dioxygenase (deaminating) activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate." [UM-BBD_enzymeID:e0392] xref: EC:1.14.12.- xref: GO:0018604 xref: UM-BBD_enzymeID:e0392 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003797 name: 2-aminobenzenesulfonate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene-4-sulfonate + NADH + H+ + O2 = NAD+ + HSO3(-) + 4-methylcatechol." [UM-BBD_enzymeID:e0241] synonym: "2-aminobenzenesulphonate dioxygenase activity" EXACT [] xref: EC:1.14.12.- xref: GO:0018605 xref: UM-BBD_enzymeID:e0241 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003798 name: benzenesulfonate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol." [UM-BBD_enzymeID:e0242] synonym: "benzenesulphonate dioxygenase activity" EXACT [] xref: EC:1.14.12.- xref: GO:0018606 xref: UM-BBD_enzymeID:e0242 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003799 name: 1-indanone monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin." [UM-BBD_enzymeID:e0298] xref: EC:1.14.12.- xref: GO:0018607 xref: UM-BBD_enzymeID:e0298 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003800 name: 1-indanone dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone." [UM-BBD_enzymeID:e0296] xref: EC:1.14.12.- xref: GO:0018608 xref: UM-BBD_enzymeID:e0296 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003801 name: chlorobenzene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene)." [UM-BBD_enzymeID:e0062] xref: EC:1.14.12.- xref: GO:0018609 xref: UM-BBD_enzymeID:e0062 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003802 name: dibenzofuran 4,4a-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+." [MetaCyc:R606-RXN] xref: EC:1.14.12.- xref: GO:0018610 xref: MetaCyc:R606-RXN xref: UM-BBD_enzymeID:e0030 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003803 name: toluate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate." [UM-BBD_enzymeID:e0190] xref: EC:1.14.12.- xref: GO:0018611 xref: UM-BBD_enzymeID:e0190 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003804 name: dibenzothiophene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene." [UM-BBD_enzymeID:e0160] xref: EC:1.14.12.- xref: GO:0018612 xref: UM-BBD_enzymeID:e0160 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003805 name: 9-fluorenone dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone." [UM-BBD_enzymeID:e0293] xref: EC:1.14.12.- xref: GO:0018613 xref: UM-BBD_enzymeID:e0293 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003806 name: ethylbenzene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene." [UM-BBD_enzymeID:e0217] xref: EC:1.14.12.- xref: GO:0018614 xref: UM-BBD_enzymeID:e0217 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003807 name: 2-indanone monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone." [UM-BBD_enzymeID:e0299] xref: EC:1.14.12.- xref: GO:0018615 xref: UM-BBD_enzymeID:e0299 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003808 name: trihydroxytoluene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate." [MetaCyc:R305-RXN, UM-BBD_enzymeID:e0074] xref: EC:1.14.12.- xref: GO:0018616 xref: MetaCyc:R305-RXN xref: UM-BBD_enzymeID:e0074 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003809 name: 4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol." [UM-BBD_enzymeID:e0393] synonym: "4-aminobenzenesulphonate 3,4-dioxygenase (deaminating) activity" EXACT [] xref: EC:1.14.12.- xref: GO:0018617 xref: UM-BBD_enzymeID:e0393 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003810 name: anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3." [EC:1.14.12.1] subset: gosubset_prok synonym: "AntA" RELATED [] synonym: "AntB" RELATED [] synonym: "AntC" RELATED [] synonym: "anthranilate 1,2-dioxygenase" RELATED [] synonym: "anthranilate dioxygenase activity" EXACT [] synonym: "anthranilate dioxygenase reductase" NARROW [] synonym: "anthranilate hydroxylase activity" BROAD [EC:1.14.12.1] synonym: "anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)" EXACT [EC:1.14.12.1] synonym: "anthranilic acid hydroxylase activity" BROAD [EC:1.14.12.1] synonym: "anthranilic hydroxylase activity" BROAD [EC:1.14.12.1] xref: EC:1.14.12.1 xref: GO:0018618 xref: MetaCyc:1.14.12.1-RXN xref: UM-BBD_enzymeID:e0371 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003811 name: benzene 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: benzene + NADH + H+ + O2 = cis-cyclohexa-3,5-diene-1,2-diol + NAD+." [EC:1.14.12.3] subset: gosubset_prok synonym: "benzene dioxygenase activity" EXACT [EC:1.14.12.3] synonym: "benzene hydroxylase activity" RELATED [EC:1.14.12.3] synonym: "benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.3] xref: EC:1.14.12.3 xref: GO:0018619 xref: MetaCyc:BENZENE-1 xref: UM-BBD_enzymeID:e0059 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003812 name: phthalate 4,5-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+." [EC:1.14.12.7] subset: gosubset_prok synonym: "PDO activity" EXACT [EC:1.14.12.7] synonym: "phthalate dioxygenase activity" BROAD [EC:1.14.12.7] synonym: "phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating)" EXACT [EC:1.14.12.7] xref: EC:1.14.12.7 xref: GO:0018620 xref: MetaCyc:PHTHALATE-4 xref: UM-BBD_enzymeID:e0104 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003813 name: 4-sulfobenzoate 3,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-sulfobenzoate + NADH + H+ + O2 = 3,4-dihydroxybenzoate + SO3(2-) (sulfite) + NAD+." [EC:1.14.12.8] synonym: "4-sulfobenzoate 3,4-dioxygenase system" RELATED [EC:1.14.12.8] synonym: "4-sulfobenzoate dioxygenase activity" EXACT [EC:1.14.12.8] synonym: "4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming)" EXACT [EC:1.14.12.8] synonym: "4-sulphobenzoate 3,4-dioxygenase activity" EXACT [] xref: EC:1.14.12.8 xref: GO:0018621 xref: MetaCyc:4-SULFOBENZOATE-3 xref: UM-BBD_enzymeID:e0128 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003814 name: 4-chlorophenylacetate 3,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-chlorophenyl acetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD+." [EC:1.14.12.9] synonym: "4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)" EXACT [EC:1.14.12.9] xref: EC:1.14.12.9 xref: GO:0018622 xref: MetaCyc:1.14.12.9-RXN xref: UM-BBD_enzymeID:e0290 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003815 name: benzoate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+." [EC:1.14.12.10] subset: gosubset_prok synonym: "benzoate dioxygenase activity" EXACT [EC:1.14.12.10] synonym: "benzoate hydroxylase activity" EXACT [EC:1.14.12.10] synonym: "benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.10] synonym: "benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)" EXACT [EC:1.14.12.10] synonym: "benzoic hydroxylase activity" EXACT [EC:1.14.12.10] xref: EC:1.14.12.10 xref: GO:0018623 xref: MetaCyc:BENZOATE-1 xref: UM-BBD_enzymeID:e0154 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003816 name: toluene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene + NADH + H+ + O2 = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+." [EC:1.14.12.11] synonym: "toluene 1,2-dioxygenase activity" EXACT [EC:1.14.12.11] synonym: "toluene 2,3-dioxygenase activity" EXACT [EC:1.14.12.11] synonym: "toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.11] xref: EC:1.14.12.11 xref: GO:0018624 xref: MetaCyc:TOLUENE-DIOXYGENASE-RXN xref: UM-BBD_enzymeID:e0155 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003817 name: naphthalene 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+." [EC:1.14.12.12] subset: gosubset_prok synonym: "naphthalene dioxygenase activity" EXACT [EC:1.14.12.12] synonym: "naphthalene oxygenase activity" EXACT [EC:1.14.12.12] synonym: "naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.12] xref: EC:1.14.12.12 xref: GO:0018625 xref: MetaCyc:NAPHTHALENE-1 xref: UM-BBD_enzymeID:e0002 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003818 name: 2-chlorobenzoate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2." [EC:1.14.12.13] subset: gosubset_prok synonym: "2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)" EXACT [EC:1.14.12.13] synonym: "2-halobenzoate 1,2-dioxygenase activity" EXACT [] xref: EC:1.14.12.13 xref: GO:0018626 xref: MetaCyc:2-CHLOROBENZOATE-1 xref: UM-BBD_enzymeID:e0036 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003819 name: 2-aminobenzenesulfonate 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-aminobenzenesulfonate + NADH + H+ + O2 = 2,3-dihydroxybenzenesulfonate + NH3 + NAD+." [EC:1.14.12.14] synonym: "2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)" EXACT [EC:1.14.12.14] synonym: "2-aminobenzenesulphonate 2,3-dioxygenase activity" EXACT [] synonym: "2-aminosulfobenzene 2,3-dioxygenase activity" EXACT [EC:1.14.12.14] xref: EC:1.14.12.14 xref: GO:0018627 xref: MetaCyc:2ASDOSALCAL-RXN xref: UM-BBD_enzymeID:e0192 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003820 name: terephthalate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: terephthalate + NADH + H+ + O2 = (1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate + NAD+." [EC:1.14.12.15] synonym: "1,4-dicarboxybenzoate 1,2-dioxygenase activity" EXACT [EC:1.14.12.15] synonym: "benzene-1,4-dicarboxylate 1,2-dioxygenase activity" EXACT [EC:1.14.12.15] synonym: "benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)" EXACT [EC:1.14.12.15] xref: EC:1.14.12.15 xref: GO:0018628 xref: MetaCyc:1.14.12.15-RXN xref: UM-BBD_enzymeID:e0107 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003821 name: 2-hydroxyquinoline 5,6-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+." [EC:1.14.12.16] synonym: "2-oxo-1,2-dihydroquinoline 5,6-dioxygenase activity" EXACT [] synonym: "quinolin-2(1H)-one 5,6-dioxygenase activity" EXACT [EC:1.14.12.16] synonym: "quinolin-2-ol 5,6-dioxygenase activity" EXACT [EC:1.14.12.16] synonym: "quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating)" EXACT [EC:1.14.12.16] xref: EC:1.14.12.16 xref: GO:0018629 xref: MetaCyc:1.14.12.16-RXN xref: UM-BBD_enzymeID:e0046 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003822 name: 3,5-xylenol methylhydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol." [UM-BBD_enzymeID:e0287] xref: EC:1.14.13.- xref: GO:0018630 xref: MetaCyc:3-5-XYLENOL-METHYLHYDROXYLASE-RXN xref: UM-BBD_enzymeID:e0287 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003823 name: phenylacetate hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate." [UM-BBD_enzymeID:e0197] xref: EC:1.14.13.- xref: GO:0018631 xref: UM-BBD_enzymeID:e0197 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003824 name: 4-nitrophenol 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + NO2(-) (nitrite) + p-benzoquinone." [UM-BBD_enzymeID:e0201] xref: EC:1.14.13.- xref: GO:0018632 xref: UM-BBD_enzymeID:e0201 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003825 name: dimethyl sulfide monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde." [UM-BBD_enzymeID:e0189] synonym: "dimethyl sulphide monooxygenase activity" EXACT [] xref: EC:1.14.13.- xref: GO:0018633 xref: UM-BBD_enzymeID:e0189 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003826 name: alpha-pinene monooxygenase [NADH] activity namespace: molecular_function def: "Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide." [UM-BBD_enzymeID:e0443] xref: EC:1.14.13.- xref: GO:0018634 xref: UM-BBD_enzymeID:e0443 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003827 name: limonene 1,2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-(4R)-limonene + NADH + O2 = NAD+ + OH- + (4R)-limonene-1,2-epoxide." [UM-BBD_enzymeID:e0462] xref: EC:1.14.13.- xref: GO:0018635 xref: UM-BBD_enzymeID:e0462 is_a: CCO:F0004059 ! limonene monooxygenase activity [Term] id: CCO:F0003828 name: phenanthrene 9,10-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide." [UM-BBD_enzymeID:e0334] xref: EC:1.14.13.- xref: GO:0018636 xref: UM-BBD_enzymeID:e0334 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003829 name: 1-hydroxy-2-naphthoate hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene." [UM-BBD_enzymeID:e0332] xref: EC:1.14.13.- xref: GO:0018637 xref: UM-BBD_enzymeID:e0332 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003830 name: toluene 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene." [UM-BBD_enzymeID:e0225] xref: EC:1.14.13.- xref: GO:0018638 xref: UM-BBD_enzymeID:e0225 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003831 name: xylene monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene + 1/2 O2 = benzyl alcohol or xylene + 1/2 O2 = methylbenzyl alcohol." [UM-BBD_enzymeID:e0172] xref: EC:1.14.13.- xref: GO:0018639 xref: UM-BBD_enzymeID:e0172 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003832 name: dibenzothiophene monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O." [MetaCyc:RXN-621] xref: EC:1.14.13.- xref: GO:0018640 xref: MetaCyc:RXN-621 xref: UM-BBD_enzymeID:e0214 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003833 name: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline." [UM-BBD_enzymeID:e0043] xref: EC:1.14.13.- xref: GO:0018641 xref: UM-BBD_enzymeID:e0043 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003834 name: chlorophenol 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol." [UM-BBD_enzymeID:e0252] xref: EC:1.14.13.- xref: GO:0018642 xref: UM-BBD_enzymeID:e0252 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003835 name: carbon disulfide oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide." [UM-BBD_enzymeID:e0401] synonym: "carbon disulphide oxygenase activity" EXACT [] xref: EC:1.14.13.- xref: GO:0018643 xref: UM-BBD_enzymeID:e0401 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003836 name: toluene 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene." [UM-BBD_enzymeID:e0222] xref: EC:1.14.13.- xref: GO:0018644 xref: MetaCyc:TOLUENE-2-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0222 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003837 name: alkene monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O." [EC:1.14.13.69] synonym: "alkene epoxygenase activity" EXACT [EC:1.14.13.69] synonym: "alkene,NADH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.69] xref: EC:1.14.13.69 xref: GO:0018645 xref: MetaCyc:1.14.13.69-RXN xref: UM-BBD_enzymeID:e0039 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003838 name: 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate." [UM-BBD_enzymeID:e0464] xref: EC:1.14.13.- xref: GO:0018646 xref: UM-BBD_enzymeID:e0464 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003839 name: phenanthrene 1,2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide." [UM-BBD_enzymeID:e0333] xref: EC:1.14.13.- xref: GO:0018647 xref: UM-BBD_enzymeID:e0333 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003840 name: methanesulfonic acid monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: methanesulfonic acid + O2 + NADH = OH- + NAD+ + sulfurous acid + formaldehyde." [UM-BBD_enzymeID:e0264] synonym: "methanesulphonic acid monooxygenase activity" EXACT [] xref: EC:1.14.13.- xref: GO:0018648 xref: UM-BBD_enzymeID:e0264 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003841 name: tetrahydrofuran hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran." [UM-BBD_enzymeID:e0015] xref: EC:1.14.13.- xref: GO:0018649 xref: UM-BBD_enzymeID:e0015 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003842 name: styrene monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide." [UM-BBD_enzymeID:e0195] xref: EC:1.14.13.- xref: GO:0018650 xref: UM-BBD_enzymeID:e0195 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003843 name: toluene-4-sulfonate monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene." [UM-BBD_enzymeID:e0243] synonym: "toluene-4-sulphonate monooxygenase activity" EXACT [] xref: EC:1.14.13.- xref: GO:0018651 xref: UM-BBD_enzymeID:e0243 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003844 name: toluene-sulfonate methyl-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol." [UM-BBD_enzymeID:e0238] synonym: "toluene-sulphonate methyl-monooxygenase activity" EXACT [] xref: EC:1.14.13.- xref: GO:0018652 xref: UM-BBD_enzymeID:e0238 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003845 name: 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline." [EC:1.14.13.-] xref: EC:1.14.13.- xref: GO:0018653 xref: UM-BBD_enzymeID:e0042 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003846 name: 2-hydroxy-phenylacetate hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate." [UM-BBD_enzymeID:e0198] xref: EC:1.14.13.- xref: GO:0018654 xref: UM-BBD_enzymeID:e0198 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003847 name: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA." [UM-BBD_enzymeID:e0304] xref: EC:1.14.13.- xref: GO:0018655 xref: UM-BBD_enzymeID:e0304 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003848 name: phenanthrene 3,4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide." [UM-BBD_enzymeID:e0347] xref: EC:1.14.13.- xref: GO:0018656 xref: UM-BBD_enzymeID:e0347 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003849 name: toluene 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene." [UM-BBD_enzymeID:e0224] xref: EC:1.14.13.- xref: GO:0018657 xref: MetaCyc:TOLUENE-3-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0224 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003850 name: salicylate 1-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2." [EC:1.14.13.1] subset: gosubset_prok synonym: "salicylate 1-hydroxylase activity" EXACT [EC:1.14.13.1] synonym: "salicylate hydroxylase (decarboxylating)" EXACT [EC:1.14.13.1] synonym: "salicylate hydroxylase activity" EXACT [] synonym: "salicylate monooxygenase activity" EXACT [EC:1.14.13.1] synonym: "salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)" EXACT [EC:1.14.13.1] synonym: "salicylic hydroxylase activity" EXACT [EC:1.14.13.1] xref: EC:1.14.13.1 xref: GO:0018658 xref: MetaCyc:SALICYLATE-1-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0149 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003851 name: 4-hydroxybenzoate 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O." [EC:1.14.13.2] subset: gosubset_prok synonym: "4-hydroxybenzoate 3-hydroxylase activity" BROAD [EC:1.14.13.2] synonym: "4-hydroxybenzoate monooxygenase activity" EXACT [EC:1.14.13.2] synonym: "4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.2] synonym: "p-hydroxybenzoate hydrolyase activity" EXACT [EC:1.14.13.2] synonym: "p-hydroxybenzoate hydroxylase activity" BROAD [EC:1.14.13.2] synonym: "p-hydroxybenzoate-3-hydroxylase activity" EXACT [EC:1.14.13.2] synonym: "p-hydroxybenzoic acid hydrolase activity" EXACT [EC:1.14.13.2] synonym: "p-hydroxybenzoic acid hydroxylase activity" BROAD [EC:1.14.13.2] synonym: "p-hydroxybenzoic hydroxylase activity" EXACT [EC:1.14.13.2] synonym: "para-hydroxybenzoate hydroxylase activity" BROAD [EC:1.14.13.2] xref: EC:1.14.13.2 xref: GO:0018659 xref: MetaCyc:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0084 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003852 name: 4-hydroxyphenylacetate 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O." [EC:1.14.13.3] subset: gosubset_prok synonym: "4 HPA 3-hydroxylase activity" EXACT [EC:1.14.13.3] synonym: "4-hydroxyphenylacetate 3-hydroxylase activity" EXACT [] synonym: "4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.3] synonym: "4-hydroxyphenylacetic acid-3-hydroxylase activity" EXACT [EC:1.14.13.3] synonym: "p-hydroxyphenylacetate 3-hydroxylase activity" EXACT [EC:1.14.13.3] synonym: "p-hydroxyphenylacetate hydroxylase activity" EXACT [EC:1.14.13.3] xref: EC:1.14.13.3 xref: GO:0018660 xref: MetaCyc:1.14.13.3-RXN xref: UM-BBD_enzymeID:e0150 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003853 name: orcinol 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: orcinol + NADH + H+ + O2 = 2,3,5-trihydroxytoluene + NAD+ + H2O." [EC:1.14.13.6] synonym: "orcinol hydroxylase activity" EXACT [] synonym: "orcinol,NADH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.6] xref: EC:1.14.13.6 xref: GO:0018661 xref: MetaCyc:ORCINOL-2-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0073 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003854 name: phenol 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O." [EC:1.14.13.7] subset: gosubset_prok synonym: "phenol hydroxylase activity" EXACT [EC:1.14.13.7] synonym: "phenol o-hydroxylase activity" EXACT [EC:1.14.13.7] synonym: "phenol,NADPH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.7] xref: EC:1.14.13.7 xref: GO:0018662 xref: MetaCyc:PHENOL-2-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0208 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003855 name: 2,6-dihydroxypyridine 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,6-dihydroxypyridine + NADH + H+ + O2 = 2,3,6-trihydroxypyridine + NAD+ + H2O." [EC:1.14.13.10] synonym: "2,6-dihydroxypyridine oxidase activity" EXACT [] synonym: "2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.10] xref: EC:1.14.13.10 xref: GO:0018663 xref: MetaCyc:1.14.13.10-RXN xref: UM-BBD_enzymeID:e0340 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003856 name: benzoate 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: benzoate + NADPH + H+ + O2 = 4-hydroxybenzoate + NADP+ + H2O." [EC:1.14.13.12] synonym: "4-hydroxybenzoic hydroxylase activity" EXACT [] synonym: "benzoate 4-hydroxylase activity" EXACT [EC:1.14.13.12] synonym: "benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.13.12] synonym: "benzoate-p-hydroxylase activity" EXACT [EC:1.14.13.12] synonym: "benzoate-para-hydroxylase activity" EXACT [EC:1.14.13.12] synonym: "benzoic 4-hydroxylase activity" EXACT [EC:1.14.13.12] synonym: "benzoic acid 4-hydroxylase activity" EXACT [EC:1.14.13.12] synonym: "p-hydroxybenzoate hydroxylase activity" EXACT [EC:1.14.13.12] xref: EC:1.14.13.12 xref: GO:0018664 xref: MetaCyc:BENZOATE-4-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0414 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003857 name: 4-hydroxyphenylacetate 1-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O." [EC:1.14.13.18] synonym: "4-HPA 1-hydroxylase activity" EXACT [EC:1.14.13.18] synonym: "4-hydroxyphenyl-acetate 1-hydroxylase activity" EXACT [] synonym: "4-hydroxyphenylacetate 1-hydroxylase activity" EXACT [EC:1.14.13.18] synonym: "4-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating)" EXACT [EC:1.14.13.18] synonym: "4-hydroxyphenylacetic 1-hydroxylase activity" EXACT [EC:1.14.13.18] xref: EC:1.14.13.18 xref: GO:0018665 xref: MetaCyc:1.14.13.18-RXN xref: UM-BBD_enzymeID:e0151 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003858 name: 2,4-dichlorophenol 6-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O." [EC:1.14.13.20] subset: gosubset_prok synonym: "2,4-dichlorophenol hydroxylase activity" EXACT [] synonym: "2,4-dichlorophenol monooxygenase activity" EXACT [EC:1.14.13.20] synonym: "2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.20] xref: EC:1.14.13.20 xref: GO:0018666 xref: MetaCyc:2 xref: UM-BBD_enzymeID:e0152 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003859 name: cyclohexanone monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O." [EC:1.14.13.22] subset: gosubset_prok synonym: "cyclohexanone 1,2-monooxygenase activity" EXACT [] synonym: "cyclohexanone oxygenase activity" EXACT [EC:1.14.13.22] synonym: "cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity" EXACT [EC:1.14.13.22] synonym: "cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)" EXACT [EC:1.14.13.22] xref: EC:1.14.13.22 xref: GO:0018667 xref: MetaCyc:CYCLOHEXANONE-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0166 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003860 name: 3-hydroxybenzoate 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxybenzoate + NADPH + H+ + O2 = 3,4-dihydroxybenzoate + NADP+ + H2O." [EC:1.14.13.23] synonym: "3-hydroxybenzoate 4-hydroxylase activity" EXACT [] synonym: "3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.13.23] xref: EC:1.14.13.23 xref: GO:0018668 xref: MetaCyc:3-HYDROXYBENZOATE-4-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0109 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003861 name: 3-hydroxybenzoate 6-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxybenzoate + NADH + H+ + O2 = 2,5-dihydroxybenzoate + NAD+ + H2O." [EC:1.14.13.24] synonym: "3-hydroxybenzoate 6-hydroxylase activity" EXACT [] synonym: "3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.24] synonym: "3-hydroxybenzoic acid-6-hydroxylase activity" EXACT [EC:1.14.13.24] synonym: "m-hydroxybenzoate 6-hydroxylase activity" EXACT [EC:1.14.13.24] xref: EC:1.14.13.24 xref: GO:0018669 xref: MetaCyc:3-HYDROXYBENZOATE-6-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0289 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003862 name: 4-aminobenzoate 1-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2." [EC:1.14.13.27] synonym: "4-aminobenzoate dehydrogenase activity" EXACT [EC:1.14.13.27] synonym: "4-aminobenzoate hydroxylase activity" EXACT [] synonym: "4-aminobenzoate monooxygenase activity" EXACT [EC:1.14.13.27] synonym: "4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)" EXACT [EC:1.14.13.27] xref: EC:1.14.13.27 xref: GO:0018670 xref: MetaCyc:4-AMINOBENZOATE-1-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0400 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003863 name: 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O." [EC:1.14.13.33] synonym: "4-hydroxybenzoate 3-hydroxylase activity" BROAD [EC:1.14.13.33] synonym: "4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate))" EXACT [] synonym: "4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.33] synonym: "4-hydroxybenzoate-3-hydroxylase activity" EXACT [EC:1.14.13.33] xref: EC:1.14.13.33 xref: GO:0018671 xref: MetaCyc:1.14.13.33-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003864 name: anthranilate 3-monooxygenase (deaminating) activity namespace: molecular_function def: "Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = 2,3-dihydroxybenzoate + NADP+ + NH3." [EC:1.14.13.35] synonym: "anthranilate 2,3-dioxygenase (deaminating)" EXACT [EC:1.14.13.35] synonym: "anthranilate 2,3-hydroxylase (deaminating) activity" EXACT [EC:1.14.13.35] synonym: "anthranilate hydroxylase (deaminating) activity" EXACT [] synonym: "anthranilate hydroxylase activity" BROAD [EC:1.14.13.35] synonym: "anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating)" EXACT [EC:1.14.13.35] xref: EC:1.14.13.35 xref: GO:0018672 xref: MetaCyc:1.14.13.35-RXN xref: UM-BBD_enzymeID:e0382 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003865 name: anthraniloyl-CoA monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+." [EC:1.14.13.40] subset: gosubset_prok synonym: "2-aminobenzoyl-CoA monooxygenase/reductase activity" EXACT [EC:1.14.13.40] synonym: "2-aminobenzoyl-CoA,NAD(P)H:oxygen oxidoreductase (de-aromatizing)" EXACT [EC:1.14.13.40] synonym: "anthraniloyl coenzyme A reductase activity" EXACT [EC:1.14.13.40] xref: EC:1.14.13.40 xref: GO:0018673 xref: MetaCyc:ANTHRANILOYL-COA-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0370 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003869 name: pentachlorophenol monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride." [EC:1.14.13.50] subset: gosubset_prok synonym: "PCB 4-monooxygenase activity" EXACT [EC:1.14.13.50] synonym: "PCB4MO activity" EXACT [EC:1.14.13.50] synonym: "PCP hydroxylase activity" EXACT [EC:1.14.13.50] synonym: "PcpB" RELATED [EC:1.14.13.50] synonym: "pentachlorophenol 4-monooxygenase activity" EXACT [] synonym: "pentachlorophenol dechlorinase activity" EXACT [EC:1.14.13.50] synonym: "pentachlorophenol dehalogenase activity" EXACT [EC:1.14.13.50] synonym: "pentachlorophenol hydroxylase activity" EXACT [] synonym: "pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating)" EXACT [EC:1.14.13.50] xref: EC:1.14.13.50 xref: GO:0018677 xref: MetaCyc:PENTACHLOROPHENOL-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0148 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003870 name: 4-hydroxybenzoate 1-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2." [EC:1.14.13.64] synonym: "4-hydroxybenzoate 1-monooxygenase activity" EXACT [] synonym: "4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)" EXACT [EC:1.14.13.64] xref: EC:1.14.13.64 xref: GO:0018678 xref: MetaCyc:1.14.13.64-RXN xref: UM-BBD_enzymeID:e0476 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003871 name: dibenzothiophene-5,5-dioxide monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate." [UM-BBD_enzymeID:e0215] xref: EC:1.14.14.- xref: GO:0018679 xref: UM-BBD_enzymeID:e0215 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003872 name: deethylatrazine monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine." [UM-BBD_enzymeID:e0098] xref: EC:1.14.15.- xref: GO:0018680 xref: UM-BBD_enzymeID:e0098 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003873 name: deisopropylatrazine monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 CH3CHO + 2 deisopropyldeethylatrazine." [UM-BBD_enzymeID:e0094] xref: EC:1.14.15.- xref: GO:0018681 xref: UM-BBD_enzymeID:e0094 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003874 name: atrazine monooxygenase activity namespace: molecular_function xref: EC:1.14.15.- xref: GO:0018682 xref: UM-BBD_enzymeID:e0090 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003875 name: camphor 5-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O." [EC:1.14.15.1] subset: gosubset_prok synonym: "(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.15.1] synonym: "2-bornanone 5-exo-hydroxylase activity" EXACT [EC:1.14.15.1] synonym: "bornanone 5-exo-hydroxylase activity" EXACT [EC:1.14.15.1] synonym: "camphor 5-exo-hydroxylase activity" EXACT [EC:1.14.15.1] synonym: "camphor 5-exo-methylene hydroxylase activity" EXACT [] synonym: "camphor 5-exohydroxylase activity" EXACT [EC:1.14.15.1] synonym: "camphor hydroxylase activity" EXACT [EC:1.14.15.1] synonym: "camphor methylene hydroxylase activity" EXACT [EC:1.14.15.1] synonym: "cytochrome p450-cam activity" EXACT [EC:1.14.15.1] synonym: "d-camphor monooxygenase activity" EXACT [EC:1.14.15.1] synonym: "D-camphor-exo-hydroxylase activity" EXACT [EC:1.14.15.1] synonym: "methylene hydroxylase activity" EXACT [EC:1.14.15.1] synonym: "methylene monooxygenase activity" EXACT [EC:1.14.15.1] xref: EC:1.14.15.1 xref: GO:0018683 xref: MetaCyc:R541-RXN xref: UM-BBD_enzymeID:e0300 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003876 name: camphor 1,2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-bornane-2,5-dione + reduced rubredoxin + O2 = 5-oxo-1,2-campholide + oxidized rubredoxin + H2O." [EC:1.14.15.2] synonym: "(+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)" EXACT [EC:1.14.15.2] synonym: "2,5-diketocamphane lactonizing enzyme activity" EXACT [EC:1.14.15.2] synonym: "camphor ketolactonase I activity" EXACT [EC:1.14.15.2] synonym: "ketolactonase I" RELATED [EC:1.14.15.2] synonym: "oxygenase, camphor 1,2-mono" EXACT [EC:1.14.15.2] xref: EC:1.14.15.2 xref: GO:0018684 xref: MetaCyc:CAMPHOR-1 xref: UM-BBD_enzymeID:e0302 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003877 name: alkane 1-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O." [EC:1.14.15.3] subset: gosubset_prok synonym: "1-hydroxylase activity" EXACT [EC:1.14.15.3] synonym: "alkane 1-hydroxylase activity" EXACT [] synonym: "alkane hydroxylase activity" EXACT [EC:1.14.15.3] synonym: "alkane monooxygenase activity" EXACT [EC:1.14.15.3] synonym: "alkane,reduced-rubredoxin:oxygen 1-oxidoreductase activity" EXACT [EC:1.14.15.3] synonym: "fatty acid omega-hydroxylase activity" NARROW [EC:1.14.15.3] synonym: "lauric acid omega-hydroxylase activity" NARROW [EC:1.14.15.3] synonym: "omega-hydroxylase activity" RELATED [EC:1.14.15.3] xref: EC:1.14.15.3 xref: GO:0018685 xref: MetaCyc:ALKANE-1-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0022 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003878 name: 6-hydroxy pseudo-oxynicotine monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine." [UM-BBD_enzymeID:e0342] xref: EC:1.14.18.- xref: GO:0018686 xref: UM-BBD_enzymeID:e0342 is_a: CCO:F0003299 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0003879 name: biphenyl 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD; requires Fe2+." [EC:1.14.12.18] subset: gosubset_prok synonym: "biphenyl dioxygenase activity" EXACT [EC:1.14.12.18] synonym: "biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)" EXACT [EC:1.14.12.18] xref: EC:1.14.12.18 xref: GO:0018687 xref: MetaCyc:1.14.12.18-RXN xref: UM-BBD_enzymeID:e0089 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0003880 name: DDT 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT." [UM-BBD_enzymeID:e0319] xref: EC:1.14.99.- xref: GO:0018688 xref: UM-BBD_enzymeID:e0319 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is_a: CCO:F0008070 ! dioxygenase activity [Term] id: CCO:F0003881 name: naphthalene disulfonate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene)." [UM-BBD_enzymeID:e0249] synonym: "naphthalene disulphonate 1,2-dioxygenase activity" EXACT [] xref: EC:1.14.99.- xref: GO:0018689 xref: UM-BBD_enzymeID:e0249 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003882 name: 4-methoxybenzoate monooxygenase (O-demethylating) activity namespace: molecular_function def: "Catalysis of the reaction: 4-methoxybenzoate + donor-H2 + O2 = 4-hydroxybenzoate + formaldehyde + acceptor + H2O." [EC:1.14.99.15] synonym: "4-methoxybenzoate 4-monooxygenase (O-demethylating)" EXACT [EC:1.14.99.15] synonym: "4-methoxybenzoate monooxygenase activity" EXACT [] synonym: "4-methoxybenzoate O-demethylase activity" EXACT [EC:1.14.99.15] synonym: "4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating)" EXACT [EC:1.14.99.15] synonym: "p-anisic O-demethylase activity" EXACT [EC:1.14.99.15] synonym: "piperonylate-4-O-demethylase activity" EXACT [EC:1.14.99.15] xref: EC:1.14.99.15 xref: GO:0018690 xref: MetaCyc:1.14.99.15-RXN xref: UM-BBD_enzymeID:e0103 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0003883 name: arsenite oxidase activity namespace: molecular_function def: "Catalysis of the reaction: arsenite + 10 H2O = 20 H+ + 8 e- + arsenate." [UM-BBD_enzymeID:e0037] xref: EC:1.16.-.- xref: GO:0018691 xref: UM-BBD_enzymeID:e0037 is_a: CCO:F0003304 ! oxidoreductase activity, oxidizing metal ions [Term] id: CCO:F0003884 name: ethylbenzene hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: ethylbenzene + H2O + acceptor = (S)-1-phenylethanol + reduced acceptor." [EC:1.17.99.2] synonym: "ethylbenzene dehydrogenase activity" EXACT [EC:1.17.99.2] synonym: "ethylbenzene:(acceptor) oxidoreductase activity" EXACT [EC:1.17.99.2] xref: EC:1.17.99.2 xref: GO:0018693 xref: UM-BBD_enzymeID:e0209 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0003885 name: p-cymene methyl hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol." [UM-BBD_enzymeID:e0199] xref: EC:1.17.99.- xref: GO:0018694 xref: UM-BBD_enzymeID:e0199 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0003886 name: 4-cresol dehydrogenase (hydroxylating) activity namespace: molecular_function def: "Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor." [EC:1.17.99.1] subset: gosubset_prok synonym: "4-cresol dehydrogenase activity" EXACT [] synonym: "4-cresol:acceptor oxidoreductase (methyl-hydroxylating)" EXACT [EC:1.17.99.1] synonym: "p-cresol methylhydroxylase activity" EXACT [EC:1.17.99.1] synonym: "p-cresol-(acceptor) oxidoreductase (hydroxylating) activity" EXACT [EC:1.17.99.1] xref: EC:1.17.99.1 xref: GO:0018695 xref: MetaCyc:1.17.99.1-RXN xref: UM-BBD_enzymeID:e0147 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0003887 name: carbonyl sulfide nitrogenase activity namespace: molecular_function def: "Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = H2S + carbon monoxide." [UM-BBD_enzymeID:e0402] synonym: "carbonyl sulphide nitrogenase activity" EXACT [] xref: EC:1.18.6.- xref: GO:0018697 xref: UM-BBD_enzymeID:e0402 is_a: CCO:F0003313 ! oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor [Term] id: CCO:F0003888 name: vinyl chloride reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene (ethylene)." [UM-BBD_enzymeID:e0273] xref: EC:1.97.1.- xref: GO:0018698 xref: UM-BBD_enzymeID:e0273 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003889 name: trichloroethane reductive dehalogenase activity namespace: molecular_function xref: EC:1.97.1.- xref: GO:0018699 xref: UM-BBD_enzymeID:e0271 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003890 name: 2-chloro-N-isopropylacetanilide reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide." [UM-BBD_enzymeID:e0450] xref: EC:1.97.1.- xref: GO:0018700 xref: UM-BBD_enzymeID:e0450 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003891 name: 2,5-dichlorohydroquinone reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone)." [UM-BBD_enzymeID:e0366] xref: EC:1.97.1.- xref: GO:0018701 xref: UM-BBD_enzymeID:e0366 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003892 name: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU." [UM-BBD_enzymeID:e0312] synonym: "1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene dehalogenase activity" EXACT [] synonym: "DDE dehalogenase activity" EXACT [] xref: EC:1.97.1.- xref: GO:0018702 xref: UM-BBD_enzymeID:e0312 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003893 name: 2,4-dichlorophenoxyacetate dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate." [UM-BBD_enzymeID:e0233] xref: GO:0018703 xref: UM-BBD_enzymeID:e0233 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003895 name: 1,2-dichloroethene reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride." [UM-BBD_enzymeID:e0272] synonym: "1,2-dichloroethylene reductive dehalogenase activity" EXACT [] xref: GO:0018705 xref: UM-BBD_enzymeID:e0272 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003896 name: pyrogallol hydroxytransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene." [EC:1.97.1.2] subset: gosubset_prok synonym: "1,2,3,5-tetrahydroxybenzene hydroxyltransferase activity" EXACT [EC:1.97.1.2] synonym: "1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase)" EXACT [EC:1.97.1.2] synonym: "1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase activity" EXACT [EC:1.97.1.2] synonym: "1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase activity" EXACT [EC:1.97.1.2] synonym: "1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase activity" EXACT [EC:1.97.1.2] synonym: "pyrogallol hydroxyltransferase activity" EXACT [] synonym: "transhydroxylase activity" RELATED [EC:1.97.1.2] xref: EC:1.97.1.2 xref: GO:0018706 xref: MetaCyc:1.97.1.2-RXN xref: UM-BBD_enzymeID:e0009 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0003897 name: 1-phenanthrol methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene." [UM-BBD_enzymeID:e0336] xref: EC:2.1.1.- xref: GO:0018707 xref: UM-BBD_enzymeID:e0336 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0003898 name: thiol S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether." [EC:2.1.1.9] synonym: "S-adenosyl-L-methionine:thiol S-methyltransferase activity" EXACT [EC:2.1.1.9] synonym: "thiol methyltransferase activity" EXACT [EC:2.1.1.9] synonym: "TMT" RELATED [EC:2.1.1.9] xref: EC:2.1.1.9 xref: GO:0018708 xref: MetaCyc:THIOL-S-METHYLTRANSFERASE-RXN xref: Reactome:9948 xref: UM-BBD_enzymeID:e0146 is_a: CCO:F0001759 ! S-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0003899 name: acetone carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: acetone + ATP + 2 H2O + CO2 = AMP + 2 phosphate + acetoacetate." [EC:6.4.1.6] synonym: "acetone:carbon-dioxide ligase (AMP-forming)" EXACT [EC:6.4.1.6] xref: EC:6.4.1.6 xref: GO:0018710 xref: MetaCyc:6.4.1.6-RXN is_a: CCO:F0003443 ! ligase activity, forming carbon-carbon bonds [Term] id: CCO:F0003900 name: benzoyl acetate-CoA thiolase activity namespace: molecular_function def: "Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA." [UM-BBD_enzymeID:e0213] xref: EC:2.3.1.- xref: GO:0018711 xref: UM-BBD_enzymeID:e0213 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0003901 name: 3-hydroxybutyryl-CoA thiolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA." [UM-BBD_enzymeID:e0013] xref: EC:2.3.1.- xref: GO:0018712 xref: UM-BBD_enzymeID:e0013 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0003902 name: 3-ketopimelyl-CoA thiolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA." [UM-BBD_enzymeID:e0182] xref: EC:2.3.1.- xref: GO:0018713 xref: UM-BBD_enzymeID:e0182 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0003903 name: 9-phenanthrol UDP-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP." [UM-BBD_enzymeID:e0377] xref: EC:2.4.1.- xref: GO:0018715 xref: UM-BBD_enzymeID:e0377 is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0003904 name: 1-phenanthrol glycosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O." [UM-BBD_enzymeID:e0356] xref: EC:2.4.1.- xref: GO:0018716 xref: UM-BBD_enzymeID:e0356 is_a: CCO:F0004058 ! phenanthrol glycosyltransferase activity [Term] id: CCO:F0003905 name: 9-phenanthrol glycosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O." [UM-BBD_enzymeID:e0350] xref: EC:2.4.1.- xref: GO:0018717 xref: UM-BBD_enzymeID:e0350 is_a: CCO:F0004058 ! phenanthrol glycosyltransferase activity [Term] id: CCO:F0003906 name: 1,2-dihydroxy-phenanthrene glycosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP." [UM-BBD_enzymeID:e0378] xref: EC:2.4.1.- xref: GO:0018718 xref: UM-BBD_enzymeID:e0378 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0003907 name: 6-aminohexanoate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate." [UM-BBD_enzymeID:e0318] xref: EC:2.6.1.- xref: GO:0018719 xref: UM-BBD_enzymeID:e0318 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0003908 name: phenol kinase activity namespace: molecular_function def: "Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate." [UM-BBD_enzymeID:e0157] xref: EC:2.7.1.- xref: GO:0018720 xref: UM-BBD_enzymeID:e0157 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0003909 name: trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate." [UM-BBD_enzymeID:e0369] synonym: "trans-9R,10R-dihydrodiolphenanthrene sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0018721 xref: UM-BBD_enzymeID:e0369 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0003910 name: 1-phenanthrol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate." [UM-BBD_enzymeID:e0373] synonym: "1-phenanthrol sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0018722 xref: UM-BBD_enzymeID:e0373 is_a: CCO:F0004057 ! phenanthrol sulfotransferase activity [Term] id: CCO:F0003911 name: 3-phenanthrol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate." [UM-BBD_enzymeID:e0374] synonym: "3-phenanthrol sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0018723 xref: UM-BBD_enzymeID:e0374 is_a: CCO:F0004057 ! phenanthrol sulfotransferase activity [Term] id: CCO:F0003912 name: 4-phenanthrol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate." [UM-BBD_enzymeID:e0375] synonym: "4-phenanthrol sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0018724 xref: UM-BBD_enzymeID:e0375 is_a: CCO:F0004057 ! phenanthrol sulfotransferase activity [Term] id: CCO:F0003913 name: trans-3,4-dihydrodiolphenanthrene sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate." [UM-BBD_enzymeID:e0368] synonym: "trans-3,4-dihydrodiolphenanthrene sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0018725 xref: UM-BBD_enzymeID:e0368 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0003914 name: 9-phenanthrol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate." [UM-BBD_enzymeID:e0376] synonym: "9-phenanthrol sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0018726 xref: UM-BBD_enzymeID:e0376 is_a: CCO:F0004057 ! phenanthrol sulfotransferase activity [Term] id: CCO:F0003915 name: 2-phenanthrol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate." [UM-BBD_enzymeID:e0372] synonym: "2-phenanthrol sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0018727 xref: UM-BBD_enzymeID:e0372 is_a: CCO:F0004057 ! phenanthrol sulfotransferase activity [Term] id: CCO:F0003916 name: succinyl-CoA:benzylsuccinate CoA-transferase activity namespace: molecular_function xref: EC:2.8.3.- xref: GO:0018728 xref: UM-BBD_enzymeID:e0260 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0003917 name: propionate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA." [EC:2.8.3.1] subset: gosubset_prok synonym: "acetyl-CoA:propanoate CoA-transferase activity" EXACT [EC:2.8.3.1] synonym: "propionate coenzyme A-transferase activity" EXACT [EC:2.8.3.1] synonym: "propionate-CoA:lactoyl-CoA transferase activity" EXACT [EC:2.8.3.1] synonym: "propionyl CoA:acetate CoA transferase activity" EXACT [EC:2.8.3.1] synonym: "propionyl-CoA transferase activity" EXACT [EC:2.8.3.1] xref: EC:2.8.3.1 xref: GO:0018729 xref: MetaCyc:PROPIONATE-COA-TRANSFERASE-RXN xref: UM-BBD_enzymeID:e0071 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0003918 name: glutaconate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA." [EC:2.8.3.12] subset: gosubset_prok synonym: "acetyl-CoA:(E)-glutaconate CoA-transferase activity" EXACT [EC:2.8.3.12] xref: EC:2.8.3.12 xref: GO:0018730 xref: MetaCyc:GLUTACONATE-COA-TRANSFERASE-RXN xref: UM-BBD_enzymeID:e0069 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0003919 name: 1-oxa-2-oxocycloheptane lactonase activity namespace: molecular_function def: "Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate." [UM-BBD_enzymeID:e0167] xref: EC:3.1.1.- xref: GO:0018731 xref: UM-BBD_enzymeID:e0167 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0003920 name: sulfolactone hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate." [UM-BBD_enzymeID:e0384] synonym: "sulpholactone hydrolase activity" EXACT [] xref: EC:3.1.1.- xref: GO:0018732 xref: UM-BBD_enzymeID:e0384 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0003921 name: 3,4-dihydrocoumarin hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate." [UM-BBD_enzymeID:e0297] xref: EC:3.1.1.- xref: GO:0018733 xref: UM-BBD_enzymeID:e0297 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0003922 name: butyrolactone hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate." [UM-BBD_enzymeID:e0017] xref: EC:3.1.1.- xref: GO:0018734 xref: UM-BBD_enzymeID:e0017 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0003923 name: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA." [UM-BBD_enzymeID:e0187] xref: EC:3.7.1.- xref: GO:0018736 xref: UM-BBD_enzymeID:e0187 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003924 name: 2-ketocyclohexane-1-carboxyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA." [UM-BBD_enzymeID:e0178] xref: EC:3.7.1.- xref: GO:0018737 xref: UM-BBD_enzymeID:e0178 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003925 name: S-formylglutathione hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: S-formylglutathione + H2O = glutathione + formate." [EC:3.1.2.12] subset: gosubset_prok xref: EC:3.1.2.12 xref: GO:0018738 xref: MetaCyc:S-FORMYLGLUTATHIONE-HYDROLASE-RXN xref: UM-BBD_enzymeID:e0141 is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0003926 name: 4-hydroxybenzoyl-CoA thioesterase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA." [EC:3.1.2.23] subset: gosubset_prok synonym: "4-hydroxybenzoyl-CoA hydrolase activity" EXACT [EC:3.1.2.23] synonym: "4-hydroxybenzoyl-CoA thiolesterase activity" EXACT [] xref: EC:3.1.2.23 xref: GO:0018739 xref: MetaCyc:3.1.2.23-RXN xref: UM-BBD_enzymeID:e0118 is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0003927 name: 2'-hydroxybiphenyl-2-sulfinate desulfinase activity namespace: molecular_function def: "Catalysis of the reaction: 2-(2-hydroxyphenyl)benzenesulfinate + H2O = 2-hydroxybiphenyl + SO3(2-) (sulfite)." [EC:3.13.1.3] subset: gosubset_prok synonym: "2'-hydroxybiphenyl-2-sulfinate sulfinolyase activity" EXACT [] synonym: "2'-hydroxybiphenyl-2-sulfinate sulfohydrolase activity" EXACT [EC:3.13.1.3] synonym: "2-(2'-hydroxyphenyl)benzenesulfinate desulfinase activity" EXACT [EC:3.13.1.3] synonym: "2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase activity" EXACT [EC:3.13.1.3] synonym: "2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase activity" EXACT [EC:3.13.1.3] synonym: "2-(2-hydroxyphenyl)benzenesulfinate desulfinase activity" EXACT [EC:3.13.1.3] synonym: "2-(2-hydroxyphenyl)benzenesulfinate hydrolase activity" EXACT [EC:3.13.1.3] synonym: "2-(2-hydroxyphenyl)benzenesulphinate hydrolase activity" EXACT [] synonym: "dibenzothiophene desulfurization enzyme B" RELATED [EC:3.13.1.3] synonym: "DszB" RELATED [EC:3.13.1.3] synonym: "gene dszB-encoded hydrolase activity" EXACT [EC:3.13.1.3] synonym: "HBPSi desulfinase activity" EXACT [EC:3.13.1.3] synonym: "HPBS desulfinase activity" EXACT [EC:3.13.1.3] xref: EC:3.13.1.3 xref: GO:0018740 xref: MetaCyc:RXN-624 xref: UM-BBD_enzymeID:e0216 is_a: CCO:F0006192 ! hydrolase activity, acting on carbon-sulfur bonds [Term] id: CCO:F0003928 name: alkyl sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: dodecyl sulfate + H2O = SO4(2-) (sulfate) + H+ + 1-dodecanol." [UM-BBD_enzymeID:e0403] synonym: "alkyl sulphatase activity" EXACT [] xref: EC:3.1.6.- xref: GO:0018741 xref: UM-BBD_enzymeID:e0403 is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0003929 name: epoxide hydrolase B activity namespace: molecular_function def: "Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers." [UM-BBD_enzymeID:e0051] xref: EC:3.3.2.- xref: GO:0018742 xref: UM-BBD_enzymeID:e0051 is_a: CCO:F0000723 ! epoxide hydrolase activity [Term] id: CCO:F0003930 name: phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene." [UM-BBD_enzymeID:e0367] xref: EC:3.3.2.- xref: GO:0018743 xref: UM-BBD_enzymeID:e0367 is_a: CCO:F0004065 ! phenanthrene-9,10-epoxide hydrolase activity [Term] id: CCO:F0003931 name: limonene-1,2-epoxide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide." [EC:3.3.2.8] subset: gosubset_prok synonym: "limonene oxide hydrolase activity" EXACT [EC:3.3.2.8] xref: EC:3.3.2.8 xref: GO:0018744 xref: MetaCyc:3.3.2.8-RXN xref: UM-BBD_enzymeID:e0470 is_a: CCO:F0000723 ! epoxide hydrolase activity [Term] id: CCO:F0003932 name: epoxide hydrolase A activity namespace: molecular_function def: "Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol." [UM-BBD_enzymeID:e0049] xref: EC:3.3.2.- xref: GO:0018745 xref: UM-BBD_enzymeID:e0049 is_a: CCO:F0000723 ! epoxide hydrolase activity [Term] id: CCO:F0003933 name: phenanthrene-3,4-epoxide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene." [UM-BBD_enzymeID:e0363] xref: EC:3.3.2.- xref: GO:0018746 xref: UM-BBD_enzymeID:e0363 is_a: CCO:F0004064 ! phenanthrene-epoxide hydrolase activity [Term] id: CCO:F0003934 name: phenanthrene-1,2-epoxide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene." [UM-BBD_enzymeID:e0364] xref: EC:3.3.2.- xref: GO:0018747 xref: UM-BBD_enzymeID:e0364 is_a: CCO:F0004064 ! phenanthrene-epoxide hydrolase activity [Term] id: CCO:F0003935 name: iprodione amidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate." [UM-BBD_enzymeID:e0438] xref: EC:3.5.1.- xref: GO:0018748 xref: UM-BBD_enzymeID:e0438 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0003937 name: biuret amidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3." [EC:3.5.1.84] xref: EC:3.5.1.84 xref: GO:0018750 xref: MetaCyc:R469-RXN xref: UM-BBD_enzymeID:e0088 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0003938 name: 3,5-dichlorophenylcarboximide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate." [UM-BBD_enzymeID:e0439] xref: EC:3.5.2.- xref: GO:0018751 xref: UM-BBD_enzymeID:e0439 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0003939 name: epsilon-caprolactam lactamase activity namespace: molecular_function def: "Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate." [UM-BBD_enzymeID:e0317] xref: EC:3.5.2.- xref: GO:0018752 xref: UM-BBD_enzymeID:e0317 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0003940 name: cyanuric acid amidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2." [EC:3.5.2.15] subset: gosubset_prok xref: EC:3.5.2.15 xref: GO:0018753 xref: MetaCyc:R468-RXN xref: UM-BBD_enzymeID:e0087 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0003941 name: ammelide aminohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3." [PMID:1991731] xref: EC:3.5.3.- xref: GO:0018754 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003942 name: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity namespace: molecular_function def: "2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-." [UM-BBD_reactionID:r1414] xref: EC:3.5.3.- xref: GO:0018755 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003943 name: ammeline aminohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: ammeline + H2O = ammelide + NH3." [PMID:1991731] xref: EC:3.5.3.- xref: GO:0018756 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003944 name: deisopropylhydroxyatrazine aminohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine." [UM-BBD_enzymeID:e0092] xref: EC:3.5.3.- xref: GO:0018757 xref: UM-BBD_enzymeID:e0092 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003945 name: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid." [UM-BBD_enzymeID:e0093] xref: EC:3.5.3.- xref: GO:0018758 xref: UM-BBD_enzymeID:e0093 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0003946 name: methenyltetrahydromethanopterin cyclohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = N5-formyl-5,6,7,8-tetrahydromethanopterin." [EC:3.5.4.27] subset: gosubset_prok synonym: "5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing)" EXACT [EC:3.5.4.27] synonym: "5,10-methenyltetrahydromethanopterin cyclohydrolase activity" EXACT [EC:3.5.4.27] synonym: "methenyl-H(4)MPT cyclohydrolase activity" EXACT [EC:3.5.4.27] synonym: "methenyl-H4MPT cyclohydrolase activity" EXACT [EC:3.5.4.27] synonym: "N5,N10-methenyltetrahydromethanopterin cyclohydrolase activity" EXACT [EC:3.5.4.27] xref: EC:3.5.4.27 xref: GO:0018759 xref: MetaCyc:3.5.4.27-RXN xref: UM-BBD_enzymeID:e0140 is_a: CCO:F0004139 ! cyclohydrolase activity [Term] id: CCO:F0003947 name: thiocyanate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: thiocyanate + H2O = NH3 + carbonyl sulfide." [UM-BBD_enzymeID:e0399] synonym: "thiocyanate aminohydrolase activity" EXACT [EC:3.5.5.8] xref: EC:3.5.5.8 xref: GO:0018760 xref: MetaCyc:RXN-1761 xref: UM-BBD_enzymeID:e0399 is_a: CCO:F0003384 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles [Term] id: CCO:F0003948 name: bromoxynil nitrilase activity namespace: molecular_function def: "Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxy-benzoate + NH3. Involved in the bacterial degradation of the herbicide bromoxynil." [EC:3.5.5.6] subset: gosubset_prok synonym: "3,5-dibromo-4-hydroxybenzonitrile aminohydrolase activity" EXACT [] synonym: "bromoxynil-specific nitrilase activity" EXACT [] xref: EC:3.5.5.6 xref: GO:0018761 xref: MetaCyc:3.5.5.6-RXN xref: UM-BBD_enzymeID:e0357 is_a: CCO:F0000053 ! nitrilase activity [Term] id: CCO:F0003949 name: aliphatic nitrilase activity namespace: molecular_function def: "Catalysis of the reaction: R-CN + H2O = R-COOH + NH3." [EC:3.5.5.7] subset: gosubset_prok synonym: "aliphatic nitrile aminohydrolase activity" EXACT [EC:3.5.5.7] xref: EC:3.5.5.7 xref: GO:0018762 xref: MetaCyc:3.5.5.7-RXN xref: UM-BBD_enzymeID:e0413 is_a: CCO:F0000053 ! nitrilase activity [Term] id: CCO:F0003950 name: hydroxydechloroatrazine ethylaminohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine." [EC:3.5.99.3] subset: gosubset_prok synonym: "4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase activity" EXACT [EC:3.5.99.3] synonym: "AtzB" RELATED [EC:3.5.99.3] synonym: "hydroxyatrazine ethylaminohydrolase activity" EXACT [] synonym: "hydroxyatrazine hydrolase activity" EXACT [EC:3.5.99.3] xref: EC:3.5.99.3 xref: GO:0018763 xref: MetaCyc:R122-RXN xref: UM-BBD_enzymeID:e0085 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0003951 name: N-isopropylammelide isopropylaminohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine." [EC:3.5.99.4] subset: gosubset_prok synonym: "AtzC" RELATED [EC:3.5.99.4] xref: EC:3.5.99.4 xref: GO:0018764 xref: MetaCyc:R123-RXN xref: UM-BBD_enzymeID:e0086 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0003952 name: 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate." [UM-BBD_enzymeID:e0223] xref: EC:3.7.1.- xref: GO:0018765 xref: MetaCyc:2-OH-6-OXOHEPTA-2-4-DIENOATE-HYDR-RXN xref: UM-BBD_enzymeID:e0223 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003953 name: dihydrophloroglucinol hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate." [UM-BBD_enzymeID:e0011] xref: EC:3.7.1.- xref: GO:0018766 xref: MetaCyc:R6-RXN xref: UM-BBD_enzymeID:e0011 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003954 name: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate." [UM-BBD_enzymeID:e0102] xref: EC:3.7.1.- xref: GO:0018767 xref: UM-BBD_enzymeID:e0102 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003955 name: 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoat + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate." [UM-BBD_enzymeID:e0325] xref: EC:3.7.1.- xref: GO:0018768 xref: UM-BBD_enzymeID:e0325 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003956 name: 2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate." [UM-BBD_enzymeID:e0221] xref: EC:3.7.1.- xref: GO:0018769 xref: UM-BBD_enzymeID:e0221 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003957 name: 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate + H2O = 2-(4-chlorophenyl)-3,3-dichloropropenoate." [UM-BBD_enzymeID:e0314] xref: EC:3.7.1.- xref: GO:0018770 xref: UM-BBD_enzymeID:e0314 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003958 name: 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-6-keto-nona-2,4-dienedioate + OH- = cis-2-hydroxypenta-2,4-dienoate + succinate." [UM-BBD_enzymeID:e0310] xref: EC:3.7.1.- xref: GO:0008680 xref: GO:0018771 xref: UM-BBD_enzymeID:e0310 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003959 name: trioxoheptanoate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate." [MetaCyc:R306-RXN, UM-BBD_enzymeID:e0075] xref: EC:3.7.1.- xref: GO:0018772 xref: MetaCyc:R306-RXN xref: UM-BBD_enzymeID:e0075 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003960 name: acetylpyruvate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: acetylpyruvate + H2O = acetate + pyruvate." [EC:3.7.1.6] synonym: "2,4-dioxopentanoate acetylhydrolase activity" EXACT [EC:3.7.1.6] xref: EC:3.7.1.6 xref: GO:0018773 xref: MetaCyc:ACETYLPYRUVATE-HYDROLASE-RXN xref: UM-BBD_enzymeID:e0076 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003961 name: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate." [EC:3.7.1.8] subset: gosubset_prok synonym: "2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase activity" EXACT [EC:3.7.1.8] synonym: "2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase activity" EXACT [] synonym: "HOHPDA hydrolase activity" EXACT [EC:3.7.1.8] xref: EC:3.7.1.8 xref: GO:0018774 xref: MetaCyc:3.7.1.8-RXN xref: UM-BBD_enzymeID:e0033 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003962 name: 2-hydroxymuconate-semialdehyde hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate." [EC:3.7.1.9] synonym: "2-hydroxymuconate-semialdehyde formylhydrolase activity" EXACT [EC:3.7.1.9] synonym: "2-hydroxymuconic semialdehyde hydrolase activity" EXACT [EC:3.7.1.9] synonym: "HMSH" RELATED [EC:3.7.1.9] synonym: "HOD hydrolase activity" EXACT [EC:3.7.1.9] xref: EC:3.7.1.9 xref: GO:0018775 xref: MetaCyc:3.7.1.9-RXN xref: UM-BBD_enzymeID:e0139 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0003963 name: trans-chloroacrylic acid dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde." [UM-BBD_enzymeID:e0434] xref: EC:3.8.1.- xref: GO:0018776 xref: UM-BBD_enzymeID:e0434 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003964 name: 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol)." [PMID:10464214] xref: EC:3.8.1.- xref: GO:0018777 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003965 name: DL-2 haloacid dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate." [UM-BBD_enzymeID:e0269] xref: EC:3.8.1.- xref: GO:0018778 xref: UM-BBD_enzymeID:e0269 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003967 name: dichloroacetate halidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate." [UM-BBD_enzymeID:e0268] xref: EC:3.8.1.- xref: GO:0018780 xref: UM-BBD_enzymeID:e0268 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003968 name: S-triazine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine -> 1-hydroxy-S-triazine." [UM-BBD_ruleID:bt0330] xref: EC:3.8.1.- xref: GO:0018781 xref: UM-BBD_enzymeID:e0091 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003969 name: cis-chloroacrylic acid dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde." [UM-BBD_enzymeID:e0433] xref: EC:3.8.1.- xref: GO:0018782 xref: UM-BBD_enzymeID:e0433 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003970 name: deisopropyldeethylatrazine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3." [UM-BBD_reactionID:0129] xref: EC:3.8.1.- xref: GO:0018783 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003972 name: haloacetate dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: haloacetate + H2O = glycolate + halide." [EC:3.8.1.3] subset: gosubset_prok synonym: "haloacetate halidohydrolase activity" EXACT [EC:3.8.1.3] synonym: "monohaloacetate dehalogenase activity" EXACT [EC:3.8.1.3] xref: EC:3.8.1.3 xref: GO:0018785 xref: MetaCyc:HALOACETATE-DEHALOGENASE-RXN xref: UM-BBD_enzymeID:e0006 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003973 name: haloalkane dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide." [EC:3.8.1.5] subset: gosubset_prok synonym: "1-chlorohexane halidohydrolase activity" EXACT [EC:3.8.1.5] synonym: "1-haloalkane dehalogenase activity" EXACT [EC:3.8.1.5] synonym: "1-haloalkane halidohydrolase activity" EXACT [EC:3.8.1.5] xref: EC:3.8.1.5 xref: GO:0018786 xref: MetaCyc:HALOALKANE-DEHALOGENASE-RXN xref: UM-BBD_enzymeID:e0003 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003974 name: 4-chlorobenzoyl-CoA dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride." [EC:3.8.1.7] synonym: "4-chlorobenzoyl CoA chlorohydrolase activity" EXACT [EC:3.8.1.7] xref: EC:3.8.1.7 xref: GO:0018787 xref: MetaCyc:3.8.1.7-RXN xref: UM-BBD_enzymeID:e0113 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003975 name: atrazine chlorohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: atrazine + H2O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride." [EC:3.8.1.8] subset: gosubset_prok synonym: "AtzA" RELATED [EC:3.8.1.8] xref: EC:3.8.1.8 xref: GO:0018788 xref: MetaCyc:3.8.1.8-RXN xref: UM-BBD_enzymeID:e0001 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0003976 name: cyclamate sulfohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohexylsulfamate + H2O = cyclohexylamine + SO4(2-) (sulfate)." [EC:3.10.1.2] synonym: "cyclamate sulfamatase activity" EXACT [] synonym: "cyclamate sulfamidase activity" EXACT [EC:3.10.1.2] synonym: "cyclamate sulphohydrolase activity" EXACT [] synonym: "cyclohexylsulfamate sulfamidase activity" EXACT [EC:3.10.1.2] synonym: "cyclohexylsulfamate sulfohydrolase activity" EXACT [EC:3.10.1.2] xref: EC:3.10.1.2 xref: GO:0018789 xref: MetaCyc:CYCLAMATE-SULFOHYDROLASE-RXN xref: UM-BBD_enzymeID:e0478 is_a: CCO:F0003393 ! hydrolase activity, acting on acid sulfur-nitrogen bonds [Term] id: CCO:F0003977 name: 2,3-dihydroxybenzoate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxybenzoate + H+ = CO2 + catechol." [UM-BBD_enzymeID:e0383] xref: EC:4.1.1.- xref: GO:0018790 xref: UM-BBD_enzymeID:e0383 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003978 name: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate." [UM-BBD_enzymeID:e0286] xref: EC:4.1.1.- xref: GO:0018791 xref: UM-BBD_enzymeID:e0286 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003979 name: bis(4-chlorophenyl)acetate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM." [UM-BBD_enzymeID:e0355] synonym: "DDA decarboxylase activity" EXACT [] xref: EC:4.1.1.- xref: GO:0018792 xref: UM-BBD_enzymeID:e0355 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003980 name: 3,5-dibromo-4-hydroxybenzoate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol." [UM-BBD_enzymeID:e0358] xref: EC:4.1.1.- xref: GO:0018793 xref: UM-BBD_enzymeID:e0358 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003981 name: 2-hydroxyisobutyrate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol." [UM-BBD_enzymeID:e0408] xref: EC:4.1.1.- xref: GO:0018794 xref: UM-BBD_enzymeID:e0408 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003982 name: 2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate." [UM-BBD_enzymeID:e0412] xref: EC:4.1.1.- xref: GO:0018795 xref: UM-BBD_enzymeID:e0412 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003983 name: 4,5-dihydroxyphthalate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2." [EC:4.1.1.55] subset: gosubset_prok synonym: "4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)" EXACT [EC:4.1.1.55] synonym: "4,5-dihydroxyphthalate carboxy-lyase activity" EXACT [EC:4.1.1.55] xref: EC:4.1.1.55 xref: GO:0018796 xref: MetaCyc:4 xref: UM-BBD_enzymeID:e0106 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003984 name: gallate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4,5-trihydroxybenzoate = pyrogallol + CO2." [EC:4.1.1.59] synonym: "gallate carboxy-lyase (pyrogallol-forming)" EXACT [EC:4.1.1.59] synonym: "gallate carboxy-lyase activity" EXACT [EC:4.1.1.59] synonym: "gallic acid decarboxylase activity" EXACT [] xref: EC:4.1.1.59 xref: GO:0018798 xref: MetaCyc:GALLATE-DECARBOXYLASE-RXN xref: UM-BBD_enzymeID:e0008 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003985 name: 4-hydroxybenzoate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybenzoate = phenol + CO2." [EC:4.1.1.61] subset: gosubset_prok synonym: "4-hydroxybenzoate carboxy-lyase (phenol-forming)" EXACT [EC:4.1.1.61] synonym: "4-hydroxybenzoate carboxy-lyase activity" EXACT [EC:4.1.1.61] synonym: "p-hydroxybenzoate decarboxylase activity" EXACT [EC:4.1.1.61] xref: EC:4.1.1.61 xref: GO:0018799 xref: MetaCyc:4-HYDROXYBENZOATE-DECARBOXYLASE-RXN xref: UM-BBD_enzymeID:e0138 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003986 name: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2." [EC:4.1.1.68, UniProt:Q46978] subset: gosubset_prok synonym: "5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase activity" EXACT [EC:4.1.1.68] synonym: "5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase activity" EXACT [] synonym: "5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)" EXACT [EC:4.1.1.68] synonym: "5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase activity" EXACT [EC:4.1.1.68] synonym: "HpaG-2" RELATED [] synonym: "HpaG2" RELATED [] synonym: "OPET decarboxylase activity" EXACT [] xref: EC:4.1.1.68 xref: GO:0018800 xref: MetaCyc:4.1.1.68-RXN xref: UM-BBD_enzymeID:e0137 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003987 name: glutaconyl-CoA decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: pent-2-enoyl-CoA = but-2-enoyl-CoA + CO2." [EC:4.1.1.70] subset: gosubset_prok synonym: "4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)" EXACT [EC:4.1.1.70] synonym: "4-carboxybut-2-enoyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.70] synonym: "glutaconyl coenzyme A decarboxylase activity" EXACT [EC:4.1.1.70] synonym: "pent-2-enoyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.70] xref: EC:4.1.1.70 xref: GO:0018801 xref: MetaCyc:GLUTACONYL-COA-DECARBOXYLASE-RXN xref: UM-BBD_enzymeID:e0136 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003988 name: 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde." [UM-BBD_enzymeID:e0282] xref: EC:4.1.2.- xref: GO:0018802 xref: UM-BBD_enzymeID:e0282 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003989 name: 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate." [EC:4.1.2.34] synonym: "(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity" NARROW [EC:4.1.2.34] synonym: "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.34] synonym: "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity" NARROW [EC:4.1.2.34] synonym: "2'-carboxybenzalpyruvate aldolase activity" EXACT [EC:4.1.2.34] synonym: "trans-2'-carboxybenzalpyruvate hydratase-aldolase activity" EXACT [] xref: EC:4.1.2.34 xref: GO:0018803 xref: MetaCyc:4.1.2.34-RXN xref: UM-BBD_enzymeID:e0330 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0003990 name: benzylsuccinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: fumarate + toluene = benzylsuccinate." [UM-BBD_enzymeID:e0259] synonym: "benzylsuccinate fumarate-lyase (toluene-forming)" EXACT [EC:4.1.99.11] synonym: "benzylsuccinate fumarate-lyase activity" EXACT [EC:4.1.99.11] xref: EC:4.1.99.11 xref: GO:0018805 xref: MetaCyc:RXN-863 xref: UM-BBD_enzymeID:e0259 is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0003991 name: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA." [UM-BBD_enzymeID:e0185] xref: EC:4.2.1.- xref: GO:0018807 xref: UM-BBD_enzymeID:e0185 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003992 name: cis-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity namespace: molecular_function def: "Catalysis of the reaction: cis-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde." [UM-BBD_enzymeID:e0327] xref: EC:4.2.1.- xref: GO:0018808 xref: UM-BBD_enzymeID:e0327 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003993 name: E-phenylitaconyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA." [UM-BBD_enzymeID:e0262] xref: EC:4.2.1.- xref: GO:0018809 xref: UM-BBD_enzymeID:e0262 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003994 name: trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene." [UM-BBD_enzymeID:e0164] xref: EC:4.2.1.- xref: GO:0018810 xref: UM-BBD_enzymeID:e0164 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003995 name: cyclohex-1-ene-1-carboxyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA." [MetaCyc:R266-RXN, UM-BBD_enzymeID:e0175] xref: EC:4.2.1.- xref: GO:0018811 xref: MetaCyc:R266-RXN xref: UM-BBD_enzymeID:e0175 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003996 name: 3-hydroxyacyl-CoA dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA)." [UM-BBD_ruleID:bt0291] xref: EC:4.2.1.- xref: GO:0018812 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003997 name: trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E )-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde)." [UM-BBD_enzymeID:e0257] xref: EC:4.2.1.- xref: GO:0018813 xref: UM-BBD_enzymeID:e0257 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0003998 name: phenylacetaldoxime dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (Z)-phenylacetaldehyde oxime = phenylacetonitrile + H2O." [EC:4.99.1.7, UM-BBD_enzymeID:e0437] synonym: "(Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming) activity" EXACT [EC:4.99.1.7] synonym: "(Z)-phenylacetaldehyde-oxime hydro-lyase activity" EXACT [EC:4.99.1.7] synonym: "arylacetaldoxime dehydratase activity" EXACT [EC:4.99.1.7] synonym: "OxdB" RELATED [EC:4.99.1.7] synonym: "PAOx dehydratase activity" EXACT [EC:4.99.1.7] xref: EC:4.99.1.7 xref: GO:0018814 xref: UM-BBD_enzymeID:e0437 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0003999 name: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = CH2CHCOCOOH + 2,5,6-trihydroxy-3-methylpyridine." [MetaCyc:RXN-645, UM-BBD_enzymeID:e0045] xref: EC:4.2.1.- xref: GO:0018815 xref: MetaCyc:RXN-645 xref: UM-BBD_enzymeID:e0045 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004000 name: 2-hydroxyisobutyrate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate." [UM-BBD_enzymeID:e0409] xref: EC:4.2.1.- xref: GO:0018816 xref: UM-BBD_enzymeID:e0409 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004001 name: 2-oxo-hept-3-ene-1,7-dioate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate." [UM-BBD_enzymeID:e0281] subset: gosubset_prok synonym: "2-oxo-hepta-3-ene-1,7-dioate hydratase activity" EXACT [] synonym: "2-oxo-hepta-3-ene-1,7-dioic acid hydratase activity" EXACT [] synonym: "HpaH" RELATED [] xref: EC:4.2.1.- xref: GO:0018817 xref: MetaCyc:HYDROXYHEPTA-DIENEDIOATE-HYDROXY-RXN xref: UM-BBD_enzymeID:e0281 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004002 name: acetylene hydratase activity namespace: molecular_function def: "Catalysis of the reaction: acetaldehyde = acetylene + H2O." [EC:4.2.1.112, UM-BBD_enzymeID:e0394] synonym: "acetaldehyde hydro-lyase activity" EXACT [EC:4.2.1.112] synonym: "AH" RELATED [EC:4.2.1.112] synonym: "AHy" RELATED [EC:4.2.1.112] xref: EC:4.2.1.112 xref: GO:0018818 xref: UM-BBD_enzymeID:e0394 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004003 name: lactoyl-CoA dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O." [EC:4.2.1.54] synonym: "acrylyl coenzyme A hydratase activity" EXACT [EC:4.2.1.54] synonym: "lactoyl coenzyme A dehydratase activity" EXACT [EC:4.2.1.54] synonym: "lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)" EXACT [EC:4.2.1.54] synonym: "lactoyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.54] synonym: "lactyl CoA dehydratase activity" EXACT [EC:4.2.1.54] synonym: "lactyl-coenzyme A dehydrase activity" EXACT [EC:4.2.1.54] xref: EC:4.2.1.54 xref: GO:0018819 xref: MetaCyc:LACTOYL-COA-DEHYDRATASE-RXN xref: MetaCyc:RXN-781 xref: UM-BBD_enzymeID:e0070 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004004 name: cyanamide hydratase activity namespace: molecular_function def: "Catalysis of the reaction: urea = cyanamide + H2O." [EC:4.2.1.69] synonym: "urea hydro-lyase (cyanamide-forming)" EXACT [EC:4.2.1.69] synonym: "urea hydro-lyase activity" EXACT [EC:4.2.1.69] xref: EC:4.2.1.69 xref: GO:0018820 xref: MetaCyc:CYANAMIDE-HYDRATASE-RXN xref: UM-BBD_enzymeID:e0426 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004005 name: nitrile hydratase activity namespace: molecular_function def: "Catalysis of the reaction: an aliphatic amide = a nitrile + H2O." [EC:4.2.1.84] subset: gosubset_prok synonym: "3-cyanopyridine hydratase activity" EXACT [EC:4.2.1.84] synonym: "acrylonitrile hydratase activity" EXACT [EC:4.2.1.84] synonym: "aliphatic nitrile hydratase activity" EXACT [EC:4.2.1.84] synonym: "aliphatic-amide hydro-lyase (nitrile-forming)" EXACT [EC:4.2.1.84] synonym: "H-NHase activity" EXACT [EC:4.2.1.84] synonym: "L-NHase activity" EXACT [EC:4.2.1.84] synonym: "NHase activity" EXACT [EC:4.2.1.84] synonym: "nitrile hydro-lyase activity" EXACT [EC:4.2.1.84] xref: EC:4.2.1.84 xref: GO:0018822 xref: MetaCyc:NITRILE-HYDRATASE-RXN xref: UM-BBD_enzymeID:e0067 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004006 name: cyclohexa-1,5-dienecarbonyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohex-1,5-dienecarbonyl-CoA + H2O = 6-hydroxycyclohex-1-ene-1-carbonyl-CoA." [EC:4.2.1.100] subset: gosubset_prok synonym: "6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming)" RELATED [EC:4.2.1.100] synonym: "cyclohex-1,5-diene-1-carbonyl-CoA hydratase activity" EXACT [] synonym: "cyclohexa-1,5-diene-1-carbonyl-CoA hydratase activity" EXACT [EC:4.2.1.100] synonym: "cyclohexa-1,5-diene-1-carboxyl-CoA hydratase activity" EXACT [EC:4.2.1.100] synonym: "cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.100] synonym: "dienoyl-CoA hydratase activity" EXACT [EC:4.2.1.100] xref: EC:4.2.1.100 xref: GO:0018823 xref: MetaCyc:4.2.1.100-RXN xref: UM-BBD_enzymeID:e0184 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004008 name: triethanolamine lyase activity namespace: molecular_function def: "Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde." [UM-BBD_enzymeID:e0421] xref: EC:4.3.3.- xref: GO:0018825 xref: UM-BBD_enzymeID:e0421 is_a: CCO:F0003408 ! amine-lyase activity [Term] id: CCO:F0004009 name: methionine gamma-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate." [EC:4.4.1.11] subset: gosubset_prok synonym: "L-methioninase activity" EXACT [EC:4.4.1.11] synonym: "L-methionine gamma-lyase activity" EXACT [EC:4.4.1.11] synonym: "L-methionine methanethiol-lyase (deaminating)" EXACT [EC:4.4.1.11] synonym: "L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)" EXACT [EC:4.4.1.11] synonym: "methioninase activity" EXACT [EC:4.4.1.11] synonym: "methionine dethiomethylase activity" EXACT [EC:4.4.1.11] synonym: "methionine lyase activity" EXACT [EC:4.4.1.11] xref: EC:4.4.1.11 xref: GO:0018826 xref: MetaCyc:METHIONINE-GAMMA-LYASE-RXN xref: UM-BBD_enzymeID:e0305 is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0004010 name: 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity namespace: molecular_function def: "Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU." [UM-BBD_enzymeID:e0353] synonym: "DDMS dehydrochlorinase activity" EXACT [] xref: EC:4.5.1.- xref: GO:0018827 xref: UM-BBD_enzymeID:e0353 is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004011 name: halohydrin hydrogen-halide-lyase A activity namespace: molecular_function def: "Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane." [UM-BBD_enzymeID:e0048] xref: EC:4.5.1.- xref: GO:0018828 xref: UM-BBD_enzymeID:e0048 is_a: CCO:F0004114 ! halohydrin hydrogen-halide-lyase activity [Term] id: CCO:F0004012 name: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity namespace: molecular_function def: "Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU." [UM-BBD_enzymeID:e0351] synonym: "DDD dehydrochlorinase activity" EXACT [] xref: EC:4.5.1.- xref: GO:0018829 xref: UM-BBD_enzymeID:e0351 is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004013 name: gamma-hexachlorocyclohexane dehydrochlorinase activity namespace: molecular_function def: "Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene." [UM-BBD_enzymeID:e0359] xref: EC:4.5.1.- xref: GO:0018830 xref: UM-BBD_enzymeID:e0359 is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004014 name: 5-chloro-1,2,4-trihydroxybenzene dechlorinase activity namespace: molecular_function def: "Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone." [UM-BBD_enzymeID:e0425] xref: EC:4.5.1.- xref: GO:0018831 xref: UM-BBD_enzymeID:e0425 is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004015 name: halohydrin hydrogen-halide-lyase B activity namespace: molecular_function def: "Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane." [UM-BBD_enzymeID:e0050] xref: EC:4.5.1.- xref: GO:0018832 xref: UM-BBD_enzymeID:e0050 is_a: CCO:F0004114 ! halohydrin hydrogen-halide-lyase activity [Term] id: CCO:F0004016 name: DDT-dehydrochlorinase activity namespace: molecular_function def: "Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + chloride." [EC:4.5.1.1] synonym: "1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]" RELATED [EC:4.5.1.1] synonym: "1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity" EXACT [EC:4.5.1.1] synonym: "DDT dehydrochlorinase activity" EXACT [] synonym: "DDT-as" RELATED [EC:4.5.1.1] synonym: "DDT-ase activity" EXACT [EC:4.5.1.1] synonym: "DDTase activity" EXACT [EC:4.5.1.1] xref: EC:4.5.1.1 xref: GO:0018833 xref: MetaCyc:DDT-DEHYDROCHLORINASE-RXN xref: UM-BBD_enzymeID:e0311 is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004017 name: dichloromethane dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: dichloromethane + H2O = formaldehyde + 2 chloride." [EC:4.5.1.3] subset: gosubset_prok synonym: "dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)" EXACT [EC:4.5.1.3] synonym: "dichloromethane chloride-lyase (chloride-hydrolysing)" EXACT [EC:4.5.1.3] xref: EC:4.5.1.3 xref: GO:0018834 xref: MetaCyc:DICHLOROMETHANE-DEHALOGENASE-RXN xref: UM-BBD_enzymeID:e0174 is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004018 name: carbon phosphorus lyase activity namespace: molecular_function def: "Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate)." [UM-BBD_enzymeID:e0057] xref: EC:4.99.1.- xref: GO:0009456 xref: GO:0018835 xref: UM-BBD_enzymeID:e0057 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0004019 name: alkylmercury lyase activity namespace: molecular_function def: "Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+." [EC:4.99.1.2] subset: gosubset_prok synonym: "alkylmercury mercuric-lyase (alkane-forming)" EXACT [EC:4.99.1.2] synonym: "alkylmercury mercuric-lyase activity" EXACT [EC:4.99.1.2] synonym: "organomercurial lyase activity" EXACT [EC:4.99.1.2] synonym: "organomercury lyase activity" EXACT [EC:4.99.1.2] xref: EC:4.99.1.2 xref: GO:0018836 xref: MetaCyc:ALKYLMERCURY-LYASE-RXN xref: UM-BBD_enzymeID:e0055 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0004020 name: 2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate." [UM-BBD_enzymeID:e0344] xref: EC:5.1.2.- xref: GO:0018837 xref: UM-BBD_enzymeID:e0344 is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0004021 name: mandelate racemase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-mandelate = (R)-mandelate." [EC:5.1.2.2] subset: gosubset_prok xref: EC:5.1.2.2 xref: GO:0018838 xref: MetaCyc:MANDELATE-RACEMASE-RXN xref: UM-BBD_enzymeID:e0072 is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0004022 name: cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate." [UM-BBD_enzymeID:e0163] xref: EC:5.2.1.- xref: GO:0018839 xref: UM-BBD_enzymeID:e0163 is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0004023 name: 3-carboxymuconate cycloisomerase type II activity namespace: molecular_function def: "Catalysis of the reaction: 3-sulfomuconate = 4-sulfolactone." [UM-BBD_enzymeID:e0379] subset: gosubset_prok xref: EC:5.3.3.- xref: GO:0018842 xref: UM-BBD_enzymeID:e0379 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0004024 name: 2-hydroxytetrahydrofuran isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde." [UM-BBD_enzymeID:e0026] xref: EC:5.3.99.- xref: GO:0018844 xref: UM-BBD_enzymeID:e0026 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0004025 name: 2-hydroxychromene-2-carboxylate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = trans-o-hydroxybenzylidenepyruvate." [UM-BBD_enzymeID:e0258] xref: EC:5.3.99.- xref: GO:0018845 xref: UM-BBD_enzymeID:e0258 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0004026 name: styrene-oxide isomerase activity namespace: molecular_function def: "Catalysis of the reaction: styrene oxide = phenylacetaldehyde." [EC:5.3.99.7] synonym: "SOI activity" EXACT [EC:5.3.99.7] synonym: "styrene oxide isomerase activity" EXACT [] synonym: "styrene-oxide isomerase (epoxide-cleaving)" EXACT [EC:5.3.99.7] xref: EC:5.3.99.7 xref: GO:0018846 xref: MetaCyc:STYRENE-OXIDE-ISOMERASE-RXN xref: UM-BBD_enzymeID:e0196 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0004027 name: alpha-pinene lyase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-pinene = limonene." [UM-BBD_enzymeID:e0442] xref: EC:5.5.1.- xref: GO:0018847 xref: UM-BBD_enzymeID:e0442 is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0004028 name: pinocarveol isomerase activity namespace: molecular_function def: "Catalysis of the reaction: pinocarveol = carveol." [UM-BBD_enzymeID:e0447] xref: EC:5.5.1.- xref: GO:0018848 xref: UM-BBD_enzymeID:e0447 is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0004029 name: muconate cycloisomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate." [EC:5.5.1.1] subset: gosubset_prok synonym: "2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.1] synonym: "4-carboxymethyl-4-hydroxyisocrotonolactone lyase (decyclizing)" EXACT [EC:5.5.1.1] synonym: "cis,cis-muconate cycloisomerase activity" EXACT [EC:5.5.1.1] synonym: "cis,cis-muconate lactonizing enzyme I activity" EXACT [EC:5.5.1.1] synonym: "cis,cis-muconate-lactonizing enzyme" RELATED [EC:5.5.1.1] synonym: "muconate cycloisomerase I activity" EXACT [EC:5.5.1.1] synonym: "muconate lactonizing enzyme activity" EXACT [EC:5.5.1.1] xref: EC:5.5.1.1 xref: GO:0018849 xref: MetaCyc:MUCONATE-CYCLOISOMERASE-RXN xref: UM-BBD_enzymeID:e0133 is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0004030 name: chloromuconate cycloisomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate." [EC:5.5.1.7] subset: gosubset_prok synonym: "2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.7] synonym: "muconate cycloisomerase II activity" EXACT [EC:5.5.1.7] xref: EC:5.5.1.7 xref: GO:0018850 xref: MetaCyc:CHLOROMUCONATE-CYCLOISOMERASE-RXN xref: UM-BBD_enzymeID:e0065 is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0004031 name: alpha-pinene-oxide decyclase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal." [EC:5.5.1.10] synonym: "alpha-pinene oxide lyase activity" EXACT [] synonym: "alpha-pinene-oxide lyase (decyclizing)" EXACT [EC:5.5.1.10] xref: EC:5.5.1.10 xref: GO:0018851 xref: MetaCyc:ALPHA-PINENE-OXIDE-DECYCLASE-RXN xref: UM-BBD_enzymeID:e0471 is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0004032 name: dichloromuconate cycloisomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate." [EC:5.5.1.11] synonym: "2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.11] xref: EC:5.5.1.11 xref: GO:0018852 xref: MetaCyc:DICHLOROMUCONATE-CYCLOISOMERASE-RXN xref: UM-BBD_enzymeID:e0132 is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0004033 name: perillyl-CoA synthetase activity namespace: molecular_function def: "Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA." [UM-BBD_enzymeID:e0460] xref: EC:6.2.1.- xref: GO:0018853 xref: UM-BBD_enzymeID:e0460 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004034 name: 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA." [UM-BBD_enzymeID:e0465] xref: EC:6.2.1.- xref: GO:0018854 xref: UM-BBD_enzymeID:e0465 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004035 name: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA." [UM-BBD_enzymeID:e0303] xref: EC:6.2.1.- xref: GO:0018855 xref: UM-BBD_enzymeID:e0303 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004036 name: benzoyl acetate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: benzoyl acetate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA." [UM-BBD_enzymeID:e0212] xref: EC:6.2.1.- xref: GO:0018856 xref: UM-BBD_enzymeID:e0212 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004037 name: 2,4-dichlorobenzoate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA." [UM-BBD_enzymeID:e0110] xref: EC:6.2.1.- xref: GO:0018857 xref: UM-BBD_enzymeID:e0110 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004038 name: benzoate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA. Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the corresponding chlorobenzoates." [EC:6.2.1.25] subset: gosubset_prok synonym: "benzoate-coenzyme A ligase activity" EXACT [EC:6.2.1.25] synonym: "benzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.25] synonym: "benzoyl CoA synthetase (AMP forming)" EXACT [EC:6.2.1.25] synonym: "benzoyl-coenzyme A synthetase activity" EXACT [EC:6.2.1.25] xref: EC:6.2.1.25 xref: GO:0018858 xref: MetaCyc:BENZOATE--COA-LIGASE-RXN xref: UM-BBD_enzymeID:e0131 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004039 name: 4-hydroxybenzoate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA." [EC:6.2.1.27] subset: gosubset_prok synonym: "4-hydroxybenzoate-CoA synthetase activity" EXACT [EC:6.2.1.27] synonym: "4-hydroxybenzoate-coenzyme A ligase (AMP-forming)" EXACT [EC:6.2.1.27] synonym: "4-hydroxybenzoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.27] synonym: "4-hydroxybenzoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.27] synonym: "4-hydroxybenzoyl-CoA ligase activity" EXACT [EC:6.2.1.27] xref: EC:6.2.1.27 xref: GO:0018859 xref: MetaCyc:4-HYDROXYBENZOATE--COA-LIGASE-RXN xref: UM-BBD_enzymeID:e0130 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004040 name: anthranilate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA." [EC:6.2.1.32] subset: gosubset_prok synonym: "2-aminobenzoate coenzyme A ligase activity" EXACT [EC:6.2.1.32] synonym: "2-aminobenzoate-CoA ligase activity" EXACT [EC:6.2.1.32] synonym: "2-aminobenzoate-coenzyme A ligase activity" EXACT [EC:6.2.1.32] synonym: "anthranilate--CoA ligase activity" EXACT [] synonym: "anthranilate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.32] synonym: "anthraniloyl coenzyme A synthetase activity" EXACT [EC:6.2.1.32] xref: EC:6.2.1.32 xref: GO:0018860 xref: MetaCyc:AMINOBENZCOALIG-RXN xref: UM-BBD_enzymeID:e0129 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004041 name: 4-chlorobenzoate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. Requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway." [EC:6.2.1.33] subset: gosubset_prok synonym: "4-chlorobenzoate:CoA ligase activity" EXACT [] xref: EC:6.2.1.33 xref: GO:0018861 xref: MetaCyc:6.2.1.33-RXN xref: UM-BBD_enzymeID:e0112 is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004042 name: phenylphosphate carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate." [UM-BBD_enzymeID:e0158] xref: EC:6.4.1.- xref: GO:0018862 xref: UM-BBD_enzymeID:e0158 is_a: CCO:F0003443 ! ligase activity, forming carbon-carbon bonds [Term] id: CCO:F0004043 name: phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene." [UM-BBD_enzymeID:e0335] xref: EC:3.3.2.- xref: GO:0018863 xref: UM-BBD_enzymeID:e0335 is_a: CCO:F0004065 ! phenanthrene-9,10-epoxide hydrolase activity [Term] id: CCO:F0004044 name: guanyl nucleotide binding namespace: molecular_function def: "Interacting selectively with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0019001 xref: Reactome:6405 is_a: CCO:F0003548 ! purine nucleotide binding [Term] id: CCO:F0004045 name: GMP binding namespace: molecular_function def: "Interacting selectively with GMP, guanosine monophosphate." [GOC:ai] xref: GO:0019002 is_a: CCO:F0005024 ! guanyl ribonucleotide binding [Term] id: CCO:F0004046 name: GDP binding namespace: molecular_function def: "Interacting selectively with GDP, guanosine 5'-diphosphate." [GOC:ai] xref: GO:0019003 is_a: CCO:F0005024 ! guanyl ribonucleotide binding [Term] id: CCO:F0004047 name: N-acetylneuraminic acid phosphate synthase activity namespace: molecular_function xref: GO:0019007 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0004048 name: farnesoic acid O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine." [PMID:12135499] synonym: "S-adenosyl-methionine:farnesoic acid O-methyltransferase activity" EXACT [] xref: GO:0019010 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004049 name: viral antireceptor activity namespace: molecular_function xref: GO:0019041 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0004050 name: pyrimidine nucleotide binding namespace: molecular_function def: "Interacting selectively with pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate." [GOC:ai] xref: GO:0019103 is_a: CCO:F0000031 ! nucleotide binding [Term] id: CCO:F0004051 name: DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site." [GOC:elh, PMID:11554296] comment: Consider also annotating to the molecular function term 'damaged DNA binding ; GO:0003684'. subset: gosubset_prok synonym: "DNA glycosylase activity" EXACT [] synonym: "endonuclease VIII activity" RELATED [] xref: EC:3.2.2.- xref: GO:0008578 xref: GO:0019104 xref: Reactome:7370 is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0004052 name: N-palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0019105 is_a: CCO:F0003132 ! palmitoyltransferase activity is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0004053 name: myristoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0019107 xref: Reactome:2349 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0004054 name: aryl-aldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+." [EC:1.2.1.29] synonym: "aryl-aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.29] xref: EC:1.2.1.29 xref: GO:0019108 xref: MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0228 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004055 name: acyl-CoA reductase activity namespace: molecular_function subset: gosubset_prok xref: EC:1.3.99.- xref: GO:0019109 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0004056 name: oxidoreductase activity, acting on iron-sulfur proteins as donors, hydrogen ions as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces hydrogen ions." [GOC:jl] synonym: "oxidoreductase activity, acting on reduced ferredoxin as donor, hydrogen ions as acceptors" NARROW [] xref: EC:1.18.3 xref: EC:1.18.99 xref: GO:0016736 xref: GO:0019110 is_a: CCO:F0003311 ! oxidoreductase activity, acting on iron-sulfur proteins as donors [Term] id: CCO:F0004057 name: phenanthrol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate." [EC:2.8.2.-] synonym: "phenanthrol sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0019111 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0004058 name: phenanthrol glycosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O." [GOC:ai] xref: EC:2.4.1.- xref: GO:0019112 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0004059 name: limonene monooxygenase activity namespace: molecular_function xref: EC:1.14.13.- xref: GO:0019113 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0004060 name: catechol dioxygenase activity namespace: molecular_function subset: gosubset_prok xref: EC:1.13.11.- xref: GO:0019114 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0004061 name: benzaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+." [EC:1.2.1.28, EC:1.2.1.7] subset: gosubset_prok xref: EC:1.2.1.- xref: GO:0019115 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004062 name: hydroxy-nicotine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O2." [GOC:jl, http://umbbd.ahc.umn.edu/] subset: gosubset_prok xref: EC:1.5.3.- xref: GO:0019116 is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0004063 name: dihydroxyfluorene dioxygenase activity namespace: molecular_function xref: EC:1.13.11.- xref: GO:0019117 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0004064 name: phenanthrene-epoxide hydrolase activity namespace: molecular_function xref: EC:3.3.2.- xref: GO:0019118 is_a: CCO:F0000723 ! epoxide hydrolase activity [Term] id: CCO:F0004065 name: phenanthrene-9,10-epoxide hydrolase activity namespace: molecular_function xref: EC:3.3.2.- xref: GO:0019119 is_a: CCO:F0004064 ! phenanthrene-epoxide hydrolase activity [Term] id: CCO:F0004066 name: hydrolase activity, acting on acid halide bonds, in C-halide compounds namespace: molecular_function def: "Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:3.8.1 xref: GO:0019120 is_a: CCO:F0003391 ! hydrolase activity, acting on acid halide bonds [Term] id: CCO:F0004067 name: tripeptidyl-peptidase I activity namespace: molecular_function def: "Catalysis of the release of an N-terminal tripeptide from a polypeptide; requires acid pH." [EC:3.4.14.9] synonym: "tripeptidyl aminopeptidase activity" BROAD [EC:3.4.14.9] synonym: "tripeptidyl peptidase activity" BROAD [EC:3.4.14.9] xref: EC:3.4.14.9 xref: GO:0019131 xref: MetaCyc:3.4.14.9-RXN is_a: CCO:F0001790 ! tripeptidyl-peptidase activity [Term] id: CCO:F0004068 name: C-terminal processing peptidase activity namespace: molecular_function def: "Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala." [EC:3.4.21.102] subset: gosubset_prok synonym: "CtpA gene product (Synechocystis sp.)" RELATED [EC:3.4.21.102] synonym: "photosystem II D1 protein processing peptidase" NARROW [EC:3.4.21.102] synonym: "protease Re" RELATED [EC:3.4.21.102] synonym: "tail-specific protease activity" EXACT [EC:3.4.21.102] synonym: "Tsp protease" NARROW [EC:3.4.21.102] xref: EC:3.4.21.102 xref: GO:0019132 xref: MetaCyc:3.4.21.102-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0004069 name: choline monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O." [EC:1.14.15.7] subset: gosubset_prok synonym: "choline,reduced-ferredoxin:oxygen oxidoreductase activity" EXACT [EC:1.14.15.7] xref: EC:1.14.15.7 xref: GO:0019133 xref: MetaCyc:RXN1F-357 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0004070 name: glucosamine-1-phosphate N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + D-glucosamine 1-phosphate = CoA + N-acetyl-D-glucosamine 1-phosphate." [EC:2.3.1.157] subset: gosubset_prok synonym: "acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase activity" EXACT [EC:2.3.1.157] synonym: "acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase activity" EXACT [EC:2.3.1.157] xref: EC:2.3.1.157 xref: GO:0019134 xref: MetaCyc:2.3.1.157-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0004071 name: deoxyhypusine monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O." [EC:1.14.99.29] synonym: "deoxyhypusine dioxygenase activity" EXACT [EC:1.14.99.29] synonym: "deoxyhypusine hydroxylase activity" EXACT [] synonym: "deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.99.29] synonym: "DOHH activity" EXACT [EC:1.14.99.29] xref: EC:1.14.99.29 xref: GO:0019135 xref: MetaCyc:DEOXYHYPUSINE-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0004072 name: deoxynucleoside kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate." [EC:2.7.1.145] subset: gosubset_prok synonym: "ATP:deoxynucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.145] synonym: "D. melanogaster deoxynucleoside kinase activity" EXACT [EC:2.7.1.145] synonym: "Dm-dNK" RELATED [EC:2.7.1.145] synonym: "ms-dNK" RELATED [EC:2.7.1.145] synonym: "Ms-dNK activity" RELATED [EC:2.7.1.145] synonym: "multifunctional deoxynucleoside kinase activity" RELATED [EC:2.7.1.145] synonym: "multispecific deoxynucleoside kinase activity" RELATED [EC:2.7.1.145] synonym: "multisubstrate deoxyribonucleoside kinase activity" RELATED [EC:2.7.1.145] xref: EC:2.7.1.145 xref: GO:0019136 xref: MetaCyc:2.7.1.145-RXN is_a: CCO:F0004129 ! nucleoside kinase activity [Term] id: CCO:F0004073 name: thioglucosidase activity namespace: molecular_function def: "Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar." [EC:3.2.1.147] synonym: "myrosinase activity" EXACT [] synonym: "sinigrase activity" EXACT [] synonym: "sinigrinase activity" EXACT [] synonym: "thioglucoside glucohydrolase activity" EXACT [] xref: EC:3.2.1.147 xref: GO:0019137 xref: MetaCyc:3.2.1.147-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0004074 name: cytokinin dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor." [EC:1.5.99.12] synonym: "6-N-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [EC:1.5.99.12] synonym: "cytokinin oxidase activity" RELATED [] synonym: "N6-dimethylallyladenine:(acceptor) oxidoreductase activity" EXACT [EC:1.5.99.12] synonym: "N6-dimethylallyladenine:acceptor oxidoreductase activity" EXACT [EC:1.5.99.12] xref: EC:1.5.99.12 xref: GO:0019139 xref: GO:0046420 xref: MetaCyc:1.5.99.12-RXN xref: MetaCyc:PWY-2841 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0004075 name: inositol 3-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate." [EC:2.7.1.64] synonym: "ATP:myo-inositol 1-phosphotransferase activity" EXACT [EC:2.7.1.64] synonym: "inositol 1-kinase activity" RELATED [EC:2.7.1.64] synonym: "inositol-1-kinase (phosphorylating)" EXACT [EC:2.7.1.64] synonym: "myo-inositol 1-kinase activity" RELATED [EC:2.7.1.64] synonym: "myo-inositol 3-kinase activity" EXACT [] synonym: "myoinositol kinase activity" BROAD [EC:2.7.1.64] xref: EC:2.7.1.64 xref: GO:0019140 xref: MetaCyc:MYO-INOSITOL-1-KINASE-RXN is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0004076 name: 2-dehydropantolactone reductase (B-specific) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+." [EC:1.1.1.214] synonym: "(R)-pantolactone:NADP+ oxidoreductase (B-specific)" EXACT [EC:1.1.1.214] synonym: "2-dehydropantoyl-lactone reductase (B-specific) activity" EXACT [] synonym: "2-ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.214] synonym: "2-oxopantoyl lactone reductase" BROAD [EC:1.1.1.214] synonym: "ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.214] xref: EC:1.1.1.214 xref: GO:0019141 xref: MetaCyc:DEHYDROPANTLACRED-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004077 name: 2-hydroxyglutarate synthase activity namespace: molecular_function def: "Catalysis of the reaction: propanoyl-CoA + H2O + glyoxylate = 2-hydroxyglutarate + CoA." [EC:2.3.3.11] comment: Note that this function was formerly EC:4.1.3.9. synonym: "2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity" EXACT [EC:2.3.3.11] synonym: "2-hydroxyglutaratic synthetase activity" EXACT [EC:2.3.3.11] synonym: "2-hydroxyglutaric synthetase activity" EXACT [EC:2.3.3.11] synonym: "alpha-hydroxyglutarate synthase activity" EXACT [EC:2.3.3.11] synonym: "hydroxyglutarate synthase activity" EXACT [EC:2.3.3.11] synonym: "propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)" EXACT [EC:2.3.3.11] xref: EC:2.3.3.11 xref: GO:0019142 xref: MetaCyc:HYDGLUTSYN-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0004078 name: 3-deoxy-manno-octulosonate-8-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 3-deoxy-D-manno-octulosonate 8-phosphate + H2O = 3-deoxy-D-manno-octulosonate + phosphate." [EC:3.1.3.45] subset: gosubset_prok synonym: "3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase activity" EXACT [EC:3.1.3.45] xref: EC:3.1.3.45 xref: GO:0019143 xref: MetaCyc:KDO-8PPHOSPHAT-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0004079 name: ADP-sugar diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate." [EC:3.6.1.21] synonym: "adenosine diphosphosugar pyrophosphatase activity" EXACT [EC:3.6.1.21] synonym: "ADP-sugar pyrophosphatase activity" EXACT [EC:3.6.1.21] synonym: "ADP-sugar sugarphosphohydrolase activity" EXACT [EC:3.6.1.21] synonym: "ADPsugar pyrophosphatase activity" EXACT [EC:3.6.1.21] xref: EC:3.6.1.21 xref: GO:0019144 xref: MetaCyc:ADPSUGPPHOSPHAT-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0004080 name: aminobutyraldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+." [EC:1.2.1.19] subset: gosubset_prok synonym: "4-aminobutanal dehydrogenase activity" EXACT [EC:1.2.1.19] synonym: "4-aminobutanal:NAD+ 1-oxidoreductase activity" EXACT [EC:1.2.1.19] synonym: "4-aminobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.19] synonym: "ABAL dehydrogenase activity" EXACT [EC:1.2.1.19] synonym: "gamma-aminobutyraldehyde dehydroganase activity" EXACT [EC:1.2.1.19] xref: EC:1.2.1.19 xref: GO:0019145 xref: MetaCyc:AMINOBUTDEHYDROG-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004081 name: arabinose-5-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate." [EC:5.3.1.13] subset: gosubset_prok synonym: "arabinose phosphate isomerase activity" EXACT [EC:5.3.1.13] synonym: "D-arabinose-5-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.13] synonym: "D-arabinose-5-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.13] synonym: "phosphoarabinoisomerase activity" EXACT [EC:5.3.1.13] xref: EC:5.3.1.13 xref: GO:0019146 xref: MetaCyc:DARAB5PISOM-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0004083 name: D-cysteine desulfhydrase activity namespace: molecular_function def: "Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate." [EC:4.4.1.15] subset: gosubset_prok synonym: "D-cysteine lyase activity" EXACT [EC:4.4.1.15] synonym: "D-cysteine sulfide-lyase (deaminating)" EXACT [EC:4.4.1.15] synonym: "D-cysteine sulfide-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.15] xref: EC:4.4.1.15 xref: GO:0019148 xref: MetaCyc:DCYSDESULF-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0004084 name: 3-chloro-D-alanine dehydrochlorinase activity namespace: molecular_function def: "Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3." [EC:4.5.1.2] synonym: "3-chloro-D-alanine chloride-lyase (deaminating)" EXACT [EC:4.5.1.2] synonym: "3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.5.1.2] synonym: "beta-chloro-D-alanine dehydrochlorinase activity" EXACT [EC:4.5.1.2] xref: EC:4.5.1.2 xref: GO:0019149 xref: MetaCyc:3-CHLORO-D-ALANINE-DEHYDROCHLORINASE-RXN is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004085 name: D-ribulokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate." [EC:2.7.1.47] subset: gosubset_prok synonym: "ATP:D-ribulose 5-phosphotransferase activity" EXACT [EC:2.7.1.47] synonym: "D-ribulokinase (phosphorylating)" EXACT [EC:2.7.1.47] xref: EC:2.7.1.47 xref: GO:0019150 xref: MetaCyc:D-RIBULOKIN-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0004086 name: galactose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+." [EC:1.1.1.48] subset: gosubset_prok synonym: "beta-galactose dehydrogenase activity" EXACT [EC:1.1.1.48] synonym: "D-galactose 1-dehydrogenase activity" EXACT [] synonym: "D-galactose dehydrogenase activity" EXACT [EC:1.1.1.48] synonym: "D-galactose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.48] synonym: "NAD-dependent D-galactose dehydrogenase activity" EXACT [EC:1.1.1.48] xref: EC:1.1.1.48 xref: GO:0019151 xref: MetaCyc:GALACTODEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004087 name: acetoin dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+." [EC:1.1.1.5] subset: gosubset_prok synonym: "diacetyl reductase activity" EXACT [EC:1.1.1.5] xref: EC:1.1.1.5 xref: GO:0019152 xref: MetaCyc:ACETOINDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004088 name: protein-disulfide reductase (glutathione) activity namespace: molecular_function def: "Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol." [EC:1.8.4.2] subset: gosubset_prok synonym: "glutaredoxin reductase" RELATED [] synonym: "glutathione--insulin transhydrogenase activity" EXACT [EC:1.8.4.2] synonym: "glutathione-insulin transhydrogenase activity" EXACT [] synonym: "glutathione-protein disulfide oxidoreductase activity" EXACT [EC:1.8.4.2] synonym: "glutathione:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.4.2] synonym: "GSH-insulin transhydrogenase activity" EXACT [EC:1.8.4.2] synonym: "insulin reductase activity" EXACT [EC:1.8.4.2] synonym: "protein disulfide reductase (glutathione)" EXACT [EC:1.8.4.2] synonym: "protein disulfide transhydrogenase activity" EXACT [EC:1.8.4.2] synonym: "protein-disulfide interchange enzyme" RELATED [EC:1.8.4.2] synonym: "protein-disulfide isomerase/oxidoreductase activity" EXACT [EC:1.8.4.2] synonym: "protein-disulphide reductase (glutathione) activity" EXACT [] synonym: "reductase, protein disulfide (glutathione)" EXACT [EC:1.8.4.2] synonym: "thiol-protein disulphide oxidoreductase activity" EXACT [EC:1.8.4.2] synonym: "thiol:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.4.2] xref: EC:1.8.4.2 xref: GO:0019153 xref: MetaCyc:PRODISULFREDUCT-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0004089 name: glycolate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: glycolate + acceptor = glyoxylate + reduced acceptor." [EC:1.1.99.14] synonym: "glycolate oxidoreductase activity" EXACT [EC:1.1.99.14] synonym: "glycolate:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.1.99.14] synonym: "glycolate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.14] synonym: "glycolic acid dehydrogenase activity" EXACT [EC:1.1.99.14] xref: EC:1.1.99.14 xref: GO:0019154 xref: MetaCyc:GLYCOLATEDEHYDRO-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0004090 name: 3-(imidazol-5-yl)lactate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+." [EC:1.1.1.111] synonym: "(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.111] synonym: "imidazol-5-yl lactate dehydrogenase activity" EXACT [EC:1.1.1.111] xref: EC:1.1.1.111 xref: GO:0019155 xref: MetaCyc:IMILACTDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004091 name: isoamylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins." [EC:3.2.1.68] subset: gosubset_prok synonym: "debranching enzyme activity" BROAD [EC:3.2.1.68] synonym: "glycogen alpha-1,6-glucanohydrolase activity" EXACT [EC:3.2.1.68] xref: EC:3.2.1.68 xref: GO:0019156 xref: MetaCyc:3.2.1.68-RXN is_a: CCO:F0000604 ! glycogen debranching enzyme activity is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0004092 name: malate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate + O2 = oxaloacetate + H2O2." [EC:1.1.3.3] synonym: "(S)-malate:oxygen oxidoreductase activity" EXACT [EC:1.1.3.3] synonym: "FAD-dependent malate oxidase activity" EXACT [EC:1.1.3.3] synonym: "malic dehydrogenase II" RELATED [EC:1.1.3.3] synonym: "malic oxidase activity" EXACT [EC:1.1.3.3] xref: EC:1.1.3.3 xref: GO:0019157 xref: MetaCyc:MALOX-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0004093 name: mannokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate." [EC:2.7.1.7] subset: gosubset_prok synonym: "ATP:D-mannose 6-phosphotransferase activity" EXACT [EC:2.7.1.7] synonym: "D-fructose (D-mannose) kinase activity" EXACT [EC:2.7.1.7] synonym: "mannokinase (phosphorylating)" EXACT [EC:2.7.1.7] xref: EC:2.7.1.7 xref: GO:0019158 xref: MetaCyc:MANNKIN-RXN is_a: CCO:F0000807 ! hexokinase activity [Term] id: CCO:F0004094 name: nicotinamide-nucleotide amidase activity namespace: molecular_function def: "Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3." [EC:3.5.1.42] synonym: "nicotinamide mononucleotide amidohydrolase activity" EXACT [EC:3.5.1.42] synonym: "nicotinamide mononucleotide deamidase activity" EXACT [EC:3.5.1.42] synonym: "nicotinamide-D-ribonucleotide amidohydrolase activity" EXACT [EC:3.5.1.42] synonym: "NMN amidohydrolase" NARROW [] synonym: "NMN deamidase activity" EXACT [EC:3.5.1.42] xref: EC:3.5.1.42 xref: GO:0019159 xref: MetaCyc:NMNAMIDOHYDRO-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0004095 name: NMN nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: nicotinamide D-ribonucleotide + H2O = nicotinamide + D-ribose 5-phosphate." [EC:3.2.2.14] synonym: "nicotinamide mononucleotidase activity" EXACT [EC:3.2.2.14] synonym: "nicotinamide mononucleotide nucleosidase activity" EXACT [EC:3.2.2.14] synonym: "nicotinamide-nucleotide phosphoribohydrolase activity" EXACT [EC:3.2.2.14] synonym: "NMN glycohydrolase activity" EXACT [EC:3.2.2.14] synonym: "NMNase activity" EXACT [EC:3.2.2.14] synonym: "NMNGhase activity" EXACT [EC:3.2.2.14] xref: EC:3.2.2.14 xref: GO:0019160 xref: MetaCyc:NMNNUCLEOSID-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0004096 name: diamine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate." [EC:2.6.1.29] synonym: "amine transaminase activity" EXACT [EC:2.6.1.29] synonym: "amine-ketoacid transaminase activity" EXACT [EC:2.6.1.29] synonym: "diamine aminotransferase activity" EXACT [] synonym: "diamine-ketoglutaric transaminase activity" EXACT [EC:2.6.1.29] synonym: "diamine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.29] xref: EC:2.6.1.29 xref: GO:0019161 xref: MetaCyc:DIAMTRANSAM-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0004097 name: pyridoxamine-oxaloacetate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxamine + oxaloacetate = pyridoxal + L-aspartate." [EC:2.6.1.31] synonym: "pyridoxamine--oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.31] synonym: "pyridoxamine-oxaloacetate aminotransferase activity" EXACT [] synonym: "pyridoxamine:oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.31] xref: EC:2.6.1.31 xref: GO:0019162 xref: MetaCyc:PYROXALTRANSAM-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0004098 name: pyridoxamine-phosphate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate." [EC:2.6.1.54] synonym: "pyridoxamine 5'-phosphate transaminase activity" EXACT [EC:2.6.1.54] synonym: "pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.54] synonym: "pyridoxamine phosphate aminotransferase activity" EXACT [EC:2.6.1.54] synonym: "pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming)" EXACT [EC:2.6.1.54] synonym: "pyridoxamine-phosphate aminotransferase activity" EXACT [] xref: EC:2.6.1.54 xref: GO:0019163 xref: MetaCyc:PYRDAMPTRANS-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0004099 name: pyruvate synthase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + CoA + oxidized ferredoxin = acetyl-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.1] subset: gosubset_prok synonym: "pyruvate oxidoreductase activity" EXACT [EC:1.2.7.1] synonym: "pyruvate synthetase activity" EXACT [EC:1.2.7.1] synonym: "pyruvate-ferredoxin reductase activity" EXACT [] synonym: "pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.7.1] synonym: "pyruvate:ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.1] synonym: "pyruvic-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.1] xref: EC:1.2.7.1 xref: GO:0018696 xref: GO:0019164 xref: MetaCyc:PYRUFLAVREDUCT-RXN xref: UM-BBD_enzymeID:e0417 is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0004100 name: thiamin kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + thiamin = ADP + thiamin phosphate." [EC:2.7.1.89] synonym: "ATP:thiamin phosphotransferase activity" EXACT [EC:2.7.1.89] synonym: "ATP:thiamine phosphotransferase activity" EXACT [EC:2.7.1.89] synonym: "thiamin kinase (phosphorylating)" EXACT [EC:2.7.1.89] synonym: "thiamin phosphokinase activity" EXACT [EC:2.7.1.89] synonym: "thiamine kinase activity" EXACT [] xref: EC:2.7.1.89 xref: GO:0019165 xref: MetaCyc:THIKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0004101 name: trans-2-enoyl-CoA reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+." [EC:1.3.1.38] synonym: "acyl-CoA:NADP+ trans-2-oxidoreductase activity" EXACT [EC:1.3.1.38] synonym: "NADPH-dependent trans-2-enoyl-CoA reductase activity" EXACT [EC:1.3.1.38] synonym: "reductase, trans-enoyl coenzyme A" EXACT [EC:1.3.1.38] xref: EC:1.3.1.38 xref: GO:0019166 xref: MetaCyc:TRANSENOYLCOARED-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004102 name: 2-octaprenylphenol hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol." [MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN] xref: GO:0019168 xref: MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0004103 name: methylglyoxal reductase (NADH-dependent) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+." [EC:1.1.1.78] synonym: "(R)-lactaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.78] synonym: "D-lactaldehyde dehydrogenase activity" EXACT [] synonym: "methylglyoxal reductase activity" EXACT [] xref: EC:1.1.1.78 xref: GO:0019170 xref: MetaCyc:D-LACTALDEHYDE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004104 name: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: CH3-CHOH-CH2-[CH2]n-CO-[acyl-carrier protein] = H2O + CH3-CH-CH-[CH2]n-CO-[acyl-carrier protein]." [EC:4.2.1.-, GOC:ai] subset: gosubset_prok synonym: "3-hydroxyacyl-[acyl-carrier protein] dehydratase activity" EXACT [] synonym: "3-hydroxyacyl-ACP dehydratase activity" EXACT [] xref: EC:4.2.1.- xref: GO:0019171 xref: Reactome:76135 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004105 name: glyoxalase III activity namespace: molecular_function def: "Catalysis of the reaction: methylglyoxal + H2O = D-lactate." [MetaCyc:GLYOXIII-RXN] comment: Note that this term was reinstated from obsolete. xref: GO:0019172 xref: MetaCyc:GLYOXIII-RXN is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0004106 name: pyrimidine phosphatase activity namespace: molecular_function xref: GO:0019173 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0004107 name: tetrahydrothiophene 1-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor." [MetaCyc:THTOREDUCT-RXN] xref: GO:0019174 xref: MetaCyc:THTOREDUCT-RXN is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0004108 name: alpha-ribazole-5'-P phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-ribazole-5'-phosphate = alpha-ribazole + phosphate." [MetaCyc:RIBAZOLEPHOSPHAT-RXN] subset: gosubset_prok xref: EC:3.1.3.- xref: GO:0019175 xref: MetaCyc:RIBAZOLEPHOSPHAT-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0004109 name: dihydroneopterin monophosphate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate." [MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN] synonym: "dihydroneopterin monophosphate dephosphorylase activity" EXACT [] xref: EC:3.6.1.- xref: GO:0019176 xref: MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN is_a: CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Term] id: CCO:F0004110 name: dihydroneopterin triphosphate pyrophosphohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate." [MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN] xref: EC:3.6.1.- xref: GO:0019177 xref: MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0004111 name: NADP phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate." [MetaCyc:NADPPHOSPHAT-RXN] xref: EC:3.1.3.- xref: GO:0019178 xref: MetaCyc:NADPPHOSPHAT-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0004112 name: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity namespace: molecular_function def: "Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate." [EC:2.6.1.33] synonym: "dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase activity" EXACT [] synonym: "dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.33] synonym: "TDP-4-keto-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.33] synonym: "TDP-4-oxo-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.33] synonym: "thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase activity" EXACT [EC:2.6.1.33] synonym: "thymidine diphospho-4-amino-6-deoxyglucose aminotransferase activity" EXACT [EC:2.6.1.33] synonym: "thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.33] synonym: "thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase activity" EXACT [EC:2.6.1.33] xref: EC:2.6.1.33 xref: GO:0019179 xref: MetaCyc:2.6.1.33-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0004113 name: dTDP-4-amino-4,6-dideoxygalactose transaminase activity namespace: molecular_function def: "Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-galactose + L-glutamate." [EC:2.6.1.59] synonym: "dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.59] synonym: "dTDP-4-amino-4,6-dideoxygalactose aminotransferase activity" EXACT [EC:2.6.1.59] synonym: "dTDP-fucosamine aminotransferase activity" EXACT [] synonym: "thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase activity" EXACT [EC:2.6.1.59] synonym: "thymidine diphosphoaminodideoxygalactose aminotransferase activity" EXACT [EC:2.6.1.59] xref: EC:2.6.1.59 xref: GO:0019180 xref: MetaCyc:2.6.1.59-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0004114 name: halohydrin hydrogen-halide-lyase activity namespace: molecular_function xref: EC:4.5.1.- xref: GO:0019181 is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0004115 name: histamine-gated chloride channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0019182 is_a: CCO:F0001522 ! chloride channel activity is_a: CCO:F0002733 ! ligand-gated ion channel activity [Term] id: CCO:F0004116 name: acyl-CoA N-acyltransferase activity namespace: molecular_function xref: EC:2.3.1.- xref: GO:0019186 is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0004117 name: beta-1,4-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an beta-1,4-linkage." [GOC:mcc, PMID:8166646] xref: EC:2.4.1.- xref: GO:0019187 is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0004118 name: cellobiose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cellobiose from one side of the membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok synonym: "cellobiose permease activity" EXACT [] xref: GO:0019190 xref: GO:0019191 is_a: CCO:F0002631 ! disaccharide transmembrane transporter activity [Term] id: CCO:F0004119 name: sorbose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of sorbose from one side of the membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "sorbose porter activity" EXACT [] xref: GO:0019193 xref: GO:0019194 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0004120 name: galactosamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of galactosamine from one side of the membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative." [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] synonym: "galactosamine porter activity" EXACT [] xref: GO:0019195 xref: GO:0019196 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0004121 name: transmembrane receptor protein phosphatase activity namespace: molecular_function def: "The catalysis of phosphate removal from a phosphotyrosine using aspartic acid as a nucleophile in a metal-dependent manner." [GOC:hjd] xref: EC:3.1.3.- xref: GO:0019198 is_a: CCO:F0001086 ! phosphoprotein phosphatase activity is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0004122 name: transmembrane receptor protein kinase activity namespace: molecular_function subset: gosubset_prok xref: EC:2.7.11.- xref: GO:0019199 is_a: CCO:F0001043 ! protein kinase activity is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0004123 name: carbohydrate kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule." [GOC:jl] subset: gosubset_prok xref: GO:0019200 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0004124 name: nucleotide kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0019201 is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0004125 name: amino acid kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate." [GOC:jl] subset: gosubset_prok xref: GO:0019202 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0004126 name: carbohydrate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate." [GOC:mah] subset: gosubset_prok xref: GO:0019203 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0004127 name: nucleotide phosphatase activity namespace: molecular_function xref: GO:0019204 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0004128 name: nucleobase, nucleoside, nucleotide kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate." [GOC:jl] subset: gosubset_prok xref: GO:0019205 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0004129 name: nucleoside kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate." [GOC:ai] subset: gosubset_prok xref: GO:0019206 xref: Reactome:6991 is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0004130 name: kinase regulator activity namespace: molecular_function def: "Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:ai] subset: gosubset_prok xref: GO:0019207 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0004131 name: phosphatase regulator activity namespace: molecular_function def: "Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule." [GOC:ai] xref: GO:0019208 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0004132 name: kinase activator activity namespace: molecular_function def: "Increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:ai] subset: gosubset_prok xref: GO:0019209 is_a: CCO:F0001691 ! enzyme activator activity is_a: CCO:F0004130 ! kinase regulator activity [Term] id: CCO:F0004133 name: kinase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] subset: gosubset_prok xref: GO:0019210 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0004130 ! kinase regulator activity [Term] id: CCO:F0004134 name: phosphatase activator activity namespace: molecular_function def: "Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule." [GOC:ai] xref: GO:0019211 is_a: CCO:F0001691 ! enzyme activator activity is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0004135 name: phosphatase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule." [GOC:ai] xref: GO:0019212 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0004136 name: deacetylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule." [GOC:jl] subset: goslim_pir subset: gosubset_prok xref: GO:0019213 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0004137 name: intermediate filament binding namespace: molecular_function def: "Interacting selectively with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0019215 is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0004138 name: centromeric DNA binding namespace: molecular_function def: "Interacting selectively with centromere-associated DNA, usually characterized by highly repetitive sequences." [GOC:jl, ISBN:0321000382] synonym: "centromere binding" BROAD [] xref: GO:0019237 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0004139 name: cyclohydrolase activity namespace: molecular_function subset: gosubset_prok xref: GO:0019238 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [Term] id: CCO:F0004140 name: deaminase activity namespace: molecular_function def: "Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3)." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: goslim_pir subset: gosubset_prok xref: GO:0019239 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0004141 name: oxalate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of oxalate from one side of the membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "oxalic acid transporter" EXACT [] xref: GO:0019531 is_a: CCO:F0001551 ! dicarboxylic acid transmembrane transporter activity [Term] id: CCO:F0004142 name: toxin transporter activity namespace: molecular_function def: "Enables the directed movement of a toxin into, out of, within or between cells. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0019534 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0004143 name: ferric-vibriobactin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ferric-vibriobactin ions from one side of a membrane to the other." [GOC:ai] xref: GO:0019535 is_a: CCO:F0002777 ! siderophore-iron transmembrane transporter activity [Term] id: CCO:F0004144 name: protein-arginine N5-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues." [PMID:9873020] xref: EC:2.1.1.- xref: GO:0019702 is_a: CCO:F0003095 ! arginine N-methyltransferase activity [Term] id: CCO:F0004145 name: protein-cysteine S-myristoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an myristoyl group to a sulfur atom on the cysteine of a protein molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0019705 is_a: CCO:F0004053 ! myristoyltransferase activity is_a: CCO:F0004147 ! protein-cysteine S-acyltransferase activity [Term] id: CCO:F0004146 name: protein-cysteine S-palmitoleyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an palmitoleyl group to a sulfur atom on the cysteine of a protein molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0019706 is_a: CCO:F0003132 ! palmitoyltransferase activity is_a: CCO:F0004147 ! protein-cysteine S-acyltransferase activity [Term] id: CCO:F0004147 name: protein-cysteine S-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule." [GOC:ai] xref: EC:2.3.1.- xref: GO:0019707 is_a: CCO:F0003140 ! S-acyltransferase activity [Term] id: CCO:F0004148 name: mevaldate reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-mevalonate + NADP+ = mevaldate + NADPH + H+." [EC:1.1.1.33] synonym: "(R)-mevalonate:NADP+ oxidoreductase" EXACT [EC:1.1.1.33] synonym: "mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase" EXACT [EC:1.1.1.33] xref: EC:1.1.1.33 xref: GO:0019726 xref: MetaCyc:MEVALDATE-REDUCTASE-(NADPH)-RXN is_a: CCO:F0000892 ! mevaldate reductase activity [Term] id: CCO:F0004149 name: mevaldate reductase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-mevalonate + NAD+ = mevaldate + NADH + H+." [EC:1.1.1.32] xref: EC:1.1.1.32 xref: GO:0019727 xref: MetaCyc:MEVALDATE-REDUCTASE-RXN is_a: CCO:F0000892 ! mevaldate reductase activity [Term] id: CCO:F0004150 name: immunoglobulin receptor activity namespace: molecular_function def: "Combining with the Fc region of an immunoglobulin protein to initiate a change in cell activity." [ISBN:0198547684] synonym: "FC receptor activity" EXACT [] xref: GO:0016489 xref: GO:0019763 is_a: CCO:F0001240 ! transmembrane receptor activity is_a: CCO:F0004198 ! immunoglobulin binding [Term] id: CCO:F0004151 name: IgA receptor activity namespace: molecular_function def: "Combining with an immunoglobulin of an IgA isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0019766 is_a: CCO:F0004150 ! immunoglobulin receptor activity is_a: CCO:F0004195 ! IgA binding [Term] id: CCO:F0004152 name: IgE receptor activity namespace: molecular_function def: "Combining with an immunoglobulin of the IgE isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0019767 is_a: CCO:F0004150 ! immunoglobulin receptor activity is_a: CCO:F0004196 ! IgE binding [Term] id: CCO:F0004153 name: high affinity IgE receptor activity namespace: molecular_function def: "Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "high affinity Fc receptor activity" RELATED [] xref: GO:0019768 is_a: CCO:F0004152 ! IgE receptor activity [Term] id: CCO:F0004154 name: low affinity IgE receptor activity namespace: molecular_function def: "Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "low affinity Fc receptor activity" RELATED [] xref: GO:0019769 is_a: CCO:F0004152 ! IgE receptor activity [Term] id: CCO:F0004155 name: IgG receptor activity namespace: molecular_function def: "Combining with an immunoglobulin of an IgG isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0019770 is_a: CCO:F0004150 ! immunoglobulin receptor activity is_a: CCO:F0004197 ! IgG binding [Term] id: CCO:F0004156 name: high affinity IgG receptor activity namespace: molecular_function def: "Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "high affinity Fc receptor activity" RELATED [] xref: GO:0019771 is_a: CCO:F0004155 ! IgG receptor activity [Term] id: CCO:F0004157 name: low affinity IgG receptor activity namespace: molecular_function def: "Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region to initiate a change in cell activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "low affinity Fc receptor activity" RELATED [] xref: GO:0019772 is_a: CCO:F0004155 ! IgG receptor activity [Term] id: CCO:F0004161 name: APG12 activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] xref: GO:0019778 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0004162 name: APG8 activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] synonym: "APG7" EXACT [] xref: GO:0019779 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0004163 name: FAT10 activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] xref: GO:0019780 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0004164 name: NEDD8 activating enzyme activity namespace: molecular_function def: "Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade." [PMID:12646924] synonym: "RUB1 activating enzyme activity" EXACT [] xref: GO:0019781 xref: GO:0019944 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0004165 name: ISG15 activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] synonym: "UBE1L" NARROW [] xref: GO:0019782 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0004166 name: small conjugating protein-specific protease activity namespace: molecular_function def: "Catalysis of the hydrolysis of various forms of polymeric ubiquitin or ubiquitin-like sequences (e.g. APG8, ISG15, NEDD8, SUMO). Will remove ubiquitin-like sequences from larger leaving groups." [GOC:ma, GOC:mah] subset: gosubset_prok synonym: "ubiquitin-like specific protease activity" NARROW [] synonym: "ubiquitin-like-protein-specific protease activity" NARROW [] xref: GO:0019783 is_a: CCO:F0001784 ! cysteine-type peptidase activity [Term] id: CCO:F0004167 name: NEDD8-specific protease activity namespace: molecular_function def: "Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates." [GOC:mah] xref: GO:0019784 is_a: CCO:F0004166 ! small conjugating protein-specific protease activity [Term] id: CCO:F0004168 name: ISG15-specific protease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates." [GOC:mah] xref: GO:0019785 is_a: CCO:F0004166 ! small conjugating protein-specific protease activity [Term] id: CCO:F0004169 name: APG8-specific protease activity namespace: molecular_function def: "Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier." [GOC:mah] synonym: "APG8-PE hydrolase" RELATED [] xref: GO:0019786 is_a: CCO:F0004166 ! small conjugating protein-specific protease activity [Term] id: CCO:F0004170 name: small conjugating protein ligase activity namespace: molecular_function def: "Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin-like protein, and a substrate lysine residue. This function may be performed alone or in conjunction with an E3, ubiquitin-like protein ligase." [GOC:mah, GOC:rn, PMID:10806345, PMID:10884686] subset: gosubset_prok synonym: "E2" NARROW [] synonym: "small protein conjugating enzyme activity" EXACT [] synonym: "ubiquitin-like conjugating enzyme activity" NARROW [] synonym: "ubiquitin-like-protein ligase activity" NARROW [] xref: GO:0008639 xref: GO:0008640 xref: GO:0019787 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0004171 name: NEDD8 ligase activity namespace: molecular_function def: "Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of the small ubiquitin-related modifier NEDD8 and a substrate lysine residue." [GOC:mah] synonym: "Hub1 conjugating enzyme activity" EXACT [] synonym: "NEDD8 conjugating enzyme activity" EXACT [] synonym: "RUB1 conjugating enzyme activity" EXACT [] xref: GO:0016976 xref: GO:0019788 xref: GO:0019945 xref: GO:0042295 is_a: CCO:F0004170 ! small conjugating protein ligase activity [Term] id: CCO:F0004172 name: SUMO ligase activity namespace: molecular_function def: "Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal glycine residues of the small ubiquitin-related modifier SUMO and a substrate lysine residue, leading to the formation of predominately monosumoylated proteins with modified function." [GOC:rn, PMID:11031248, PMID:11265250] synonym: "SMT3 conjugating enzyme" EXACT [] synonym: "SUMO conjugating enzyme activity" EXACT [] xref: GO:0016930 xref: GO:0019789 xref: GO:0019949 is_a: CCO:F0004170 ! small conjugating protein ligase activity [Term] id: CCO:F0004173 name: ISG15 carrier activity namespace: molecular_function def: "Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other." [GOC:jl, http://www.copewithcytokines.de/] synonym: "interferon-stimulated gene-15 carrier activity" NARROW [] xref: GO:0019793 is_a: CCO:F0001832 ! protein transmembrane transporter activity [Term] id: CCO:F0004174 name: procollagen-proline 3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2." [EC:1.14.11.7] synonym: "procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.7] synonym: "procollagen-proline,2-oxoglutarate 3-dioxygenase activity" EXACT [EC:1.14.11.7] synonym: "proline,2-oxoglutarate 3-dioxygenase activity" EXACT [EC:1.14.11.7] synonym: "prolyl 3-hydroxylase activity" EXACT [EC:1.14.11.7] synonym: "prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity" EXACT [EC:1.14.11.7] synonym: "protocollagen proline 3-hydroxylase activity" EXACT [EC:1.14.11.7] xref: EC:1.14.11.7 xref: GO:0019797 xref: MetaCyc:PROCOLLAGEN-PROLINE-3-DIOXYGENASE-RXN is_a: CCO:F0004175 ! procollagen-proline dioxygenase activity is_a: CCO:F0004683 ! peptidyl-proline 3-dioxygenase activity [Term] id: CCO:F0004175 name: procollagen-proline dioxygenase activity namespace: molecular_function def: "Catalysis of the transfer of a hydroxyl group from 2-oxoglutarate to a prolyl residue in a collagen molecule." [EC:1.14.11.2, EC:1.14.11.7, GOC:mah] xref: EC:1.14.11.- xref: GO:0019798 is_a: CCO:F0004682 ! peptidyl-proline dioxygenase activity [Term] id: CCO:F0004176 name: tubulin N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine." [EC:2.3.1.108] synonym: "acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity" EXACT [EC:2.3.1.108] synonym: "acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity" EXACT [EC:2.3.1.108] synonym: "acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity" EXACT [EC:2.3.1.108] synonym: "alpha-tubulin acetylase activity" EXACT [EC:2.3.1.108] synonym: "alpha-tubulin acetyltransferase activity" EXACT [EC:2.3.1.108] synonym: "alpha-tubulin N-acetyltransferase activity" EXACT [EC:2.3.1.108] synonym: "TAT activity" EXACT [EC:2.3.1.108] synonym: "tubulin acetyltransferase activity" EXACT [EC:2.3.1.108] xref: EC:2.3.1.108 xref: GO:0019799 xref: MetaCyc:TUBULIN-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0005533 ! peptide N-acetyltransferase activity [Term] id: CCO:F0004177 name: bromide peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide." [EC:1.11.1.10] subset: gosubset_prok synonym: "bromoperoxidase activity" EXACT [] xref: EC:1.11.1.- xref: GO:0019806 is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0004178 name: aspartoacylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate." [EC:3.5.1.15] subset: gosubset_prok synonym: "acetyl-aspartic deaminase activity" EXACT [EC:3.5.1.15] synonym: "acylase II" RELATED [EC:3.5.1.15] synonym: "aminoacylase II activity" RELATED [EC:3.5.1.15] synonym: "N-acetylaspartate amidohydrolase activity" EXACT [EC:3.5.1.15] synonym: "N-acyl-L-aspartate amidohydrolase activity" EXACT [EC:3.5.1.15] xref: EC:3.5.1.15 xref: GO:0019807 xref: MetaCyc:ASPARTOACYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0004179 name: polyamine binding namespace: molecular_function def: "Interacting selectively with polyamines, organic compounds containing two or more amino groups." [GOC:ai] subset: gosubset_prok xref: GO:0019808 is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0004180 name: spermidine binding namespace: molecular_function def: "Interacting selectively with spermidine, N-(3-aminopropyl)-1,4-diaminobutane." [GOC:ai] xref: GO:0019809 is_a: CCO:F0004179 ! polyamine binding [Term] id: CCO:F0004181 name: putrescine binding namespace: molecular_function def: "Interacting selectively with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine." [GOC:ai] xref: GO:0019810 is_a: CCO:F0004179 ! polyamine binding [Term] id: CCO:F0004182 name: cocaine binding namespace: molecular_function def: "Interacting selectively with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0019811 is_a: CCO:F0001746 ! drug binding [Term] id: CCO:F0004183 name: oxygen binding namespace: molecular_function def: "Interacting selectively with oxygen (O2)." [GOC:jl] subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: gosubset_prok synonym: "cytochrome P450" NARROW [] synonym: "cytochrome P450 activity" RELATED [] xref: GO:0019825 xref: Reactome:4477 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0004184 name: oxygen sensor activity namespace: molecular_function def: "Interacting selectively with and responding, e.g. by conformational change, to changes in the cellular level of, oxygen (O2)." [GOC:mah] xref: GO:0019826 is_a: CCO:F0004183 ! oxygen binding [Term] id: CCO:F0004185 name: aspartic-type endopeptidase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process." [GOC:ai] synonym: "aspartic protease inhibitor activity" EXACT [] xref: GO:0019828 is_a: CCO:F0001222 ! endopeptidase inhibitor activity [Term] id: CCO:F0004186 name: cation-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in)." [GOC:ai] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "cation ABC transporter" NARROW [] synonym: "plasma membrane cation-transporting ATPase" NARROW [] xref: GO:0019829 is_a: CCO:F0001835 ! cation transmembrane transporter activity is_a: CCO:F0005698 ! ATPase activity, coupled to transmembrane movement of ions [Term] id: CCO:F0004187 name: phospholipase A2 inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the enzyme phospholipase A2." [GOC:ai] xref: GO:0019834 is_a: CCO:F0001215 ! phospholipase inhibitor activity [Term] id: CCO:F0004188 name: growth factor binding namespace: molecular_function def: "Interacting selectively with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate." [GOC:jl, http://cancerweb.ncl.ac.uk/] synonym: "neurotrophin TRK receptor activity" RELATED [] xref: GO:0019838 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004189 name: isoprenoid binding namespace: molecular_function def: "Interacting selectively with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues." [GOC:jl] subset: goslim_pir subset: gosubset_prok xref: GO:0019840 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0004190 name: retinol binding namespace: molecular_function def: "Interacting selectively with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation." [http://cancerweb.ncl.ac.uk/] synonym: "vitamin A1 alcohol binding" EXACT [] synonym: "vitamin A1 binding" EXACT [] xref: GO:0019841 is_a: CCO:F0001639 ! retinoid binding is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0004191 name: vitamin binding namespace: molecular_function def: "Interacting selectively with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] subset: goslim_pir subset: gosubset_prok xref: GO:0019842 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0004192 name: rRNA binding namespace: molecular_function def: "Interacting selectively with ribosomal RNA." [GOC:jl] subset: gosubset_prok xref: GO:0019843 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0004193 name: D-tyrosyl-tRNA hydrolase activity namespace: molecular_function xref: GO:0019851 is_a: CCO:F0000521 ! aminoacyl-tRNA hydrolase activity [Term] id: CCO:F0004194 name: calcium channel inhibitor activity namespace: molecular_function def: "The inhibition of the passage of calcium ions through a calcium channel; the function of some venoms." [GOC:ma, http://haven.isb-sib.ch/spdocann//dicterms.txt, UniProtKB:kwdictionary] xref: GO:0019855 is_a: CCO:F0001514 ! calcium channel regulator activity is_a: CCO:F0001779 ! ion channel inhibitor activity [Term] id: CCO:F0004195 name: IgA binding namespace: molecular_function def: "Interacting selectively with an immunoglobulin of an IgA isotype." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0019862 is_a: CCO:F0004198 ! immunoglobulin binding [Term] id: CCO:F0004196 name: IgE binding namespace: molecular_function def: "Interacting selectively with an immunoglobulin of the IgE isotype." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0019863 is_a: CCO:F0004198 ! immunoglobulin binding [Term] id: CCO:F0004197 name: IgG binding namespace: molecular_function def: "Interacting selectively with an immunoglobulin of an IgG isotype." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0019864 is_a: CCO:F0004198 ! immunoglobulin binding [Term] id: CCO:F0004198 name: immunoglobulin binding namespace: molecular_function def: "Interacting selectively with an immunoglobulin." [GOC:ma] xref: GO:0019865 is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0004199 name: chloride channel inhibitor activity namespace: molecular_function xref: GO:0019869 is_a: CCO:F0001779 ! ion channel inhibitor activity is_a: CCO:F0003552 ! chloride channel regulator activity [Term] id: CCO:F0004200 name: potassium channel inhibitor activity namespace: molecular_function xref: GO:0019870 is_a: CCO:F0001779 ! ion channel inhibitor activity is_a: CCO:F0002867 ! potassium channel regulator activity [Term] id: CCO:F0004201 name: sodium channel inhibitor activity namespace: molecular_function xref: GO:0019868 xref: GO:0019871 is_a: CCO:F0001779 ! ion channel inhibitor activity is_a: CCO:F0003551 ! sodium channel regulator activity [Term] id: CCO:F0004202 name: 6-aminohexanoate-cyclic-dimer hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H2O = N-(6-aminohexanoyl)-6-aminohexanoate." [EC:3.5.2.12] subset: gosubset_prok synonym: "1,8-diazacyclotetradecane-2,9-dione lactamhydrolase activity" EXACT [EC:3.5.2.12] xref: EC:3.5.2.12 xref: GO:0019874 xref: MetaCyc:3.5.2.12-RXN xref: UM-BBD_enzymeID:e0674 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0004203 name: 6-aminohexanoate-dimer hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate." [EC:3.5.1.46] subset: gosubset_prok synonym: "6-aminohexanoic acid oligomer hydrolase activity" EXACT [EC:3.5.1.46] synonym: "N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase activity" EXACT [EC:3.5.1.46] xref: EC:3.5.1.46 xref: GO:0019875 xref: MetaCyc:RXN-3962 xref: UM-BBD_enzymeID:e0673 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0004204 name: protein kinase regulator activity namespace: molecular_function def: "Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein." [GOC:ai] subset: gosubset_prok xref: GO:0019887 is_a: CCO:F0004130 ! kinase regulator activity [Term] id: CCO:F0004205 name: protein phosphatase regulator activity namespace: molecular_function def: "Modulation of the activity of a protein phosphatase enzyme." [GOC:ai] xref: GO:0019888 is_a: CCO:F0004131 ! phosphatase regulator activity [Term] id: CCO:F0004206 name: kinesin binding namespace: molecular_function def: "Interacting selectively and stoichiometrically with kinesin, a cytoplasmic protein responsible for moving vesicles and organelles towards the distal end of microtubules." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0019894 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004207 name: kinesin-associated mitochondrial adaptor activity namespace: molecular_function def: "The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria." [http://cancerweb.ncl.ac.uk/, PMID:12495622] xref: GO:0019895 is_a: CCO:F0004206 ! kinesin binding is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0004208 name: enzyme binding namespace: molecular_function def: "Interacting selectively with any enzyme." [GOC:jl] subset: gosubset_prok xref: GO:0019899 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004209 name: kinase binding namespace: molecular_function def: "Interacting selectively with a kinase, any enzyme that catalyzes the transfer of a phosphate group." [GOC:jl] xref: GO:0019900 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0004210 name: protein kinase binding namespace: molecular_function def: "Interacting selectively with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate." [GOC:jl] xref: GO:0019901 is_a: CCO:F0004209 ! kinase binding [Term] id: CCO:F0004211 name: phosphatase binding namespace: molecular_function def: "Interacting selectively with any phosphatase." [GOC:jl] subset: gosubset_prok xref: GO:0019902 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0004212 name: protein phosphatase binding namespace: molecular_function def: "Interacting selectively with any protein phosphatase." [GOC:jl] subset: gosubset_prok xref: GO:0019903 is_a: CCO:F0004211 ! phosphatase binding [Term] id: CCO:F0004213 name: protein domain specific binding namespace: molecular_function def: "Interacting selectively with a specific domain of a protein." [GOC:go_curators] subset: gosubset_prok synonym: "protein domain-specific binding" EXACT [] xref: GO:0019904 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004214 name: syntaxin binding namespace: molecular_function def: "Interacting selectively with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0019905 is_a: CCO:F0000027 ! SNARE binding [Term] id: CCO:F0004216 name: structural constituent of myelin sheath namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve." [GOC:mah] xref: GO:0019911 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0004217 name: cyclin-dependent protein kinase activating kinase activity namespace: molecular_function def: "Increases the activity of a cyclin-dependent protein kinase (CDK)." [GOC:go_curators] synonym: "CAK" EXACT [] synonym: "cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity" EXACT [] xref: EC:2.7.11.- xref: GO:0019912 xref: GO:0019913 is_a: CCO:F0001043 ! protein kinase activity is_a: CCO:F0004382 ! protein kinase activator activity [Term] id: CCO:F0004218 name: cyclin-dependent protein kinase activating kinase regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase." [GOC:ai] synonym: "cyclin-dependent protein kinase activating kinase, intrinsic regulator activity" NARROW [] xref: EC:2.7.1.- xref: GO:0019914 is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0004219 name: SUMO activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:rn, PMID:10187858, PMID:11265250] synonym: "SMT3 activating enzyme" EXACT [] synonym: "SUMO E1 activator enzyme" EXACT [] xref: GO:0017115 xref: GO:0019948 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0004221 name: cytokine binding namespace: molecular_function def: "Interacting selectively with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity." [GOC:ai, GOC:bf, ISBN:0198599471] xref: GO:0019955 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004222 name: chemokine binding namespace: molecular_function def: "Interacting selectively with a chemokine, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions." [GOC:ai] xref: GO:0019956 is_a: CCO:F0004221 ! cytokine binding [Term] id: CCO:F0004223 name: C-C chemokine binding namespace: molecular_function def: "Interacting selectively with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif." [GOC:ai] xref: GO:0019957 is_a: CCO:F0004222 ! chemokine binding [Term] id: CCO:F0004224 name: C-X-C chemokine binding namespace: molecular_function def: "Interacting selectively with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif." [GOC:ai] xref: GO:0019958 is_a: CCO:F0004222 ! chemokine binding [Term] id: CCO:F0004225 name: interleukin-8 binding namespace: molecular_function def: "Interacting selectively with interleukin-8." [GOC:jl] synonym: "IL-8 binding" EXACT [] xref: GO:0019959 is_a: CCO:F0004224 ! C-X-C chemokine binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004226 name: C-X3-C chemokine binding namespace: molecular_function def: "Interacting selectively with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif." [GOC:ai] xref: GO:0019960 is_a: CCO:F0004222 ! chemokine binding [Term] id: CCO:F0004227 name: interferon binding namespace: molecular_function def: "Interacting selectively with an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent." [http://en.wikipedia.org "Wikipedia"] xref: GO:0019961 is_a: CCO:F0004221 ! cytokine binding [Term] id: CCO:F0004229 name: interferon-gamma binding namespace: molecular_function def: "Interacting selectively with interferon-gamma. Interferon-gamma is also known as type II interferon." [GOC:add, GOC:ai, ISBN:0126896631, PMID:15546383] synonym: "type II interferon binding" EXACT [] xref: GO:0019964 is_a: CCO:F0004227 ! interferon binding [Term] id: CCO:F0004230 name: interleukin binding namespace: molecular_function def: "Interacting selectively with an interleukin." [GOC:jl] synonym: "IL binding" EXACT [] xref: GO:0019965 is_a: CCO:F0004221 ! cytokine binding [Term] id: CCO:F0004231 name: interleukin-1 binding namespace: molecular_function def: "Interacting selectively with interleukin-1." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "IL-1 binding" EXACT [] xref: GO:0019966 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004232 name: interleukin-1, Type I, activating binding namespace: molecular_function synonym: "IL-1 type I, activating binding" EXACT [] xref: GO:0019967 is_a: CCO:F0004231 ! interleukin-1 binding [Term] id: CCO:F0004233 name: interleukin-1, Type II, blocking binding namespace: molecular_function synonym: "IL-1 type II, blocking binding" EXACT [] xref: GO:0019968 is_a: CCO:F0004231 ! interleukin-1 binding [Term] id: CCO:F0004234 name: interleukin-10 binding namespace: molecular_function def: "Interacting selectively with interleukin-10." [GOC:jl] synonym: "IL-10 binding" EXACT [] xref: GO:0019969 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004235 name: interleukin-11 binding namespace: molecular_function def: "Interacting selectively with interleukin-11." [GOC:jl] synonym: "IL-11 binding" EXACT [] xref: GO:0019970 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004236 name: interleukin-12 binding namespace: molecular_function def: "Interacting selectively with interleukin-12." [GOC:jl] synonym: "IL-12 binding" EXACT [] xref: GO:0019972 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004237 name: interleukin-13 binding namespace: molecular_function def: "Interacting selectively with interleukin-13." [GOC:jl] synonym: "IL-13 binding" EXACT [] xref: GO:0019973 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004238 name: interleukin-14 binding namespace: molecular_function def: "Interacting selectively with interleukin-14." [GOC:jl] synonym: "IL-14 binding" EXACT [] xref: GO:0019974 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004239 name: interleukin-17 binding namespace: molecular_function def: "Interacting selectively with interleukin-17." [GOC:jl] synonym: "IL-17 binding" EXACT [] xref: GO:0019975 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004240 name: interleukin-2 binding namespace: molecular_function def: "Interacting selectively with interleukin-2." [GOC:jl] synonym: "IL-2 binding" EXACT [] xref: GO:0019976 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004241 name: interleukin-21 binding namespace: molecular_function def: "Interacting selectively with interleukin-21." [GOC:jl] synonym: "IL-21 binding" EXACT [] xref: GO:0019977 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004242 name: interleukin-3 binding namespace: molecular_function def: "Interacting selectively with interleukin-3." [GOC:jl] synonym: "IL-3 binding" EXACT [] xref: GO:0019978 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004243 name: interleukin-4 binding namespace: molecular_function def: "Interacting selectively with interleukin-4." [GOC:jl] synonym: "IL-4 binding" EXACT [] xref: GO:0019979 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004244 name: interleukin-5 binding namespace: molecular_function def: "Interacting selectively with interleukin-5." [GOC:jl] synonym: "IL-5 binding" EXACT [] xref: GO:0019980 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004245 name: interleukin-6 binding namespace: molecular_function def: "Interacting selectively with interleukin-6." [GOC:jl] synonym: "IL-6 binding" EXACT [] xref: GO:0019981 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004246 name: interleukin-7 binding namespace: molecular_function def: "Interacting selectively with interleukin-7." [GOC:jl] synonym: "IL-7 binding" EXACT [] xref: GO:0019982 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004247 name: interleukin-9 binding namespace: molecular_function def: "Interacting selectively with interleukin-9." [GOC:jl] synonym: "IL-9 binding" EXACT [] xref: GO:0019983 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0004248 name: diacylglycerol binding namespace: molecular_function def: "Interacting selectively with diacylglycerol, a diester of glycerol and two fatty acids." [GOC:ma] xref: GO:0019992 is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0004249 name: heme binding namespace: molecular_function def: "Interacting selectively with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring." [GOC:ai] subset: gosubset_prok synonym: "haem binding" EXACT [] xref: GO:0020037 is_a: CCO:F0006264 ! tetrapyrrole binding [Term] id: CCO:F0004250 name: passive transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0022803 is_a: CCO:F0004284 ! transmembrane transporter activity [Term] id: CCO:F0004251 name: active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "active carrier activity" EXACT [] synonym: "carrier activity" EXACT [] synonym: "permease activity" EXACT [] synonym: "pump activity" EXACT [] xref: GO:0022804 is_a: CCO:F0004284 ! transmembrane transporter activity [Term] id: CCO:F0004252 name: mobile ion carrier activity namespace: molecular_function def: "This is a type of carrier produced by bacteria. It enable passive transport by shielding the ion that is being transported from the lipid membrane. It carries an ion across the membrane by enclosing the ion and travelling across the membrane. It does not form a fully open pore across the membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "ionophore" BROAD [] xref: GO:0022809 is_a: CCO:F0004250 ! passive transmembrane transporter activity [Term] id: CCO:F0004253 name: membrane potential driven uniporter activity namespace: molecular_function def: "Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] synonym: "porter" BROAD [] xref: GO:0022810 is_a: CCO:F0004254 ! facilitated diffusion [Term] id: CCO:F0004254 name: facilitated diffusion namespace: molecular_function def: "Catalysis of the transfer of a single solute from one side of the membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] synonym: "porters" BROAD [] synonym: "uniporter activity z" EXACT [] xref: GO:0022814 is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0004255 name: large uncharged polar molecule transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a large uncharged polar molecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022815 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0004256 name: sodium ion uniporter activity namespace: molecular_function def: "Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022818 is_a: CCO:F0002562 ! sodium ion transmembrane transporter activity is_a: CCO:F0004253 ! membrane potential driven uniporter activity [Term] id: CCO:F0004257 name: potassium ion uniporter activity namespace: molecular_function def: "Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022819 is_a: CCO:F0002560 ! potassium ion transmembrane transporter activity is_a: CCO:F0004253 ! membrane potential driven uniporter activity [Term] id: CCO:F0004258 name: potassium ion symporter activity namespace: molecular_function def: "Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022820 is_a: CCO:F0002560 ! potassium ion transmembrane transporter activity is_a: CCO:F0002742 ! symporter activity [Term] id: CCO:F0004259 name: potassium ion antiporter activity namespace: molecular_function def: "Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022821 is_a: CCO:F0002560 ! potassium ion transmembrane transporter activity is_a: CCO:F0002746 ! antiporter activity [Term] id: CCO:F0004260 name: transmitter-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022824 is_a: CCO:F0002733 ! ligand-gated ion channel activity is_a: CCO:F0004267 ! transmitter-gated channel activity [Term] id: CCO:F0004261 name: phosphorylation-gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022828 is_a: CCO:F0004268 ! gated channel activity [Term] id: CCO:F0004262 name: wide pore channel activity namespace: molecular_function def: "Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "gap junction activity" NARROW [] synonym: "non-gated, wide pore channel activity" EXACT [] xref: GO:0022829 is_a: CCO:F0002725 ! channel activity [Term] id: CCO:F0004263 name: narrow pore, gated channel activity namespace: molecular_function def: "Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus." [GOC:mtg_transport, ISBN:0815340729] synonym: "ion channels" EXACT [] xref: GO:0022831 is_a: CCO:F0004273 ! narrow pore channel activity [Term] id: CCO:F0004264 name: voltage-gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022832 is_a: CCO:F0004268 ! gated channel activity [Term] id: CCO:F0004265 name: mechanically gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a mechanical stress." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022833 is_a: CCO:F0004268 ! gated channel activity [Term] id: CCO:F0004266 name: ligand-gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022834 is_a: CCO:F0004268 ! gated channel activity [Term] id: CCO:F0004267 name: transmitter-gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] synonym: "extracellular substance gated channel activity" EXACT [] synonym: "neurotransmitter-gated channel activity" EXACT [] xref: GO:0022835 is_a: CCO:F0004266 ! ligand-gated channel activity [Term] id: CCO:F0004268 name: gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus." [GOC:mtg_transport] xref: GO:0022836 is_a: CCO:F0002725 ! channel activity [Term] id: CCO:F0004269 name: substrate specific channel activity namespace: molecular_function def: "Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules." [GOC:mtg_transport] xref: GO:0022838 is_a: CCO:F0002725 ! channel activity [Term] id: CCO:F0004270 name: ion gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus." [GOC:mtg_transport] xref: GO:0022839 is_a: CCO:F0004268 ! gated channel activity [Term] id: CCO:F0004271 name: leak channel activity namespace: molecular_function def: "Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022840 is_a: CCO:F0004273 ! narrow pore channel activity [Term] id: CCO:F0004272 name: potassium ion leak channel activity namespace: molecular_function def: "Catalysis of the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022841 is_a: CCO:F0002560 ! potassium ion transmembrane transporter activity is_a: CCO:F0004271 ! leak channel activity [Term] id: CCO:F0004273 name: narrow pore channel activity namespace: molecular_function def: "Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022842 is_a: CCO:F0002725 ! channel activity [Term] id: CCO:F0004274 name: voltage-gated cation channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022843 is_a: CCO:F0001512 ! voltage-gated ion channel activity [Term] id: CCO:F0004275 name: acetylcholine-gated cation channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022848 is_a: CCO:F0004260 ! transmitter-gated ion channel activity [Term] id: CCO:F0004276 name: glutamate-gated calcium ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022849 is_a: CCO:F0004260 ! transmitter-gated ion channel activity [Term] id: CCO:F0004277 name: serotonin-gated cation channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022850 is_a: CCO:F0004260 ! transmitter-gated ion channel activity [Term] id: CCO:F0004278 name: GABA-gated chloride ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022851 is_a: CCO:F0004260 ! transmitter-gated ion channel activity [Term] id: CCO:F0004279 name: glycine-gated chloride ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022852 is_a: CCO:F0004260 ! transmitter-gated ion channel activity [Term] id: CCO:F0004280 name: active ion transmembrane transporter namespace: molecular_function def: "Catalysis of the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:def, GOC:mtg_transport, ISBN:0815340729] xref: GO:0022853 is_a: CCO:F0002557 ! ion transmembrane transporter activity is_a: CCO:F0004251 ! active transmembrane transporter activity [Term] id: CCO:F0004281 name: active large uncharged polar molecule transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022854 is_a: CCO:F0004251 ! active transmembrane transporter activity is_a: CCO:F0004255 ! large uncharged polar molecule transmembrane transporter activity [Term] id: CCO:F0004282 name: protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "glucose PTS transporter activity" EXACT [] xref: GO:0022855 is_a: CCO:F0001581 ! glucose transmembrane transporter activity is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [Term] id: CCO:F0004283 name: protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "sorbitol PTS transporter activity" EXACT [] xref: GO:0022856 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002956 ! sorbitol transmembrane transporter activity [Term] id: CCO:F0004284 name: transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a substance from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0005386 xref: GO:0015646 xref: GO:0022857 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0004285 name: alanine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022858 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0004286 name: dephosphorylation-gated channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022859 is_a: CCO:F0004268 ! gated channel activity [Term] id: CCO:F0004287 name: transmembrane electron transfer carrier namespace: molecular_function def: "Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics." [GOC:mtg_transport, ISBN:0815340729, TC:5] xref: GO:0022865 xref: TC:5 is_a: CCO:F0004284 ! transmembrane transporter activity [Term] id: CCO:F0004288 name: transmembrane 1-electron transfer carrier namespace: molecular_function def: "Enables transfer of 1 electron across a membrane." [GOC:mtg_transport, ISBN:0815340729, TC:5.B] xref: GO:0022866 is_a: CCO:F0004287 ! transmembrane electron transfer carrier [Term] id: CCO:F0004289 name: transmembrane 2-electron transfer carrier namespace: molecular_function def: "Enables transfer of 2 electrons across a membrane." [GOC:mtg_transport, ISBN:0815340729, TC:5.A] xref: GO:0022867 is_a: CCO:F0004287 ! transmembrane electron transfer carrier [Term] id: CCO:F0004290 name: protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "lactose PTS transporter activity" EXACT [] xref: GO:0022869 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002632 ! lactose transmembrane transporter activity [Term] id: CCO:F0004291 name: protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "mannose PTS transporter activity" EXACT [] xref: GO:0022870 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002958 ! mannose transmembrane transporter activity [Term] id: CCO:F0004292 name: protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "sorbose PTS transporter activity" EXACT [] xref: GO:0022871 is_a: CCO:F0001581 ! glucose transmembrane transporter activity is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0004119 ! sorbose transmembrane transporter activity [Term] id: CCO:F0004293 name: protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "mannitol PTS transporter activity" EXACT [] xref: GO:0022872 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002955 ! mannitol transmembrane transporter activity [Term] id: CCO:F0004294 name: protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "maltose PTS transporter activity" EXACT [] xref: GO:0022873 is_a: CCO:F0001589 ! maltose transmembrane transporter activity is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [Term] id: CCO:F0004295 name: protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "cellobiose PTS transporter activity" EXACT [] xref: GO:0022874 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0004118 ! cellobiose transmembrane transporter activity [Term] id: CCO:F0004296 name: protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "galactitol PTS transporter activity" EXACT [] xref: GO:0022875 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002957 ! galactitol transmembrane transporter activity [Term] id: CCO:F0004297 name: protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "galactosamine PTS transporter activity" EXACT [] xref: GO:0022876 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0004120 ! galactosamine transmembrane transporter activity [Term] id: CCO:F0004298 name: protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "fructose PTS transporter activity" EXACT [] xref: GO:0022877 is_a: CCO:F0001579 ! fructose transmembrane transporter activity is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [Term] id: CCO:F0004299 name: protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "sucrose PTS transporter activity" EXACT [] xref: GO:0022878 is_a: CCO:F0001968 ! sucrose transmembrane transporter activity is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0004119 ! sorbose transmembrane transporter activity [Term] id: CCO:F0004300 name: protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "trehalose PTS transporter activity" EXACT [] xref: GO:0022879 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002954 ! trehalose transmembrane transporter activity is_a: CCO:F0002958 ! mannose transmembrane transporter activity [Term] id: CCO:F0004301 name: protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "N-acetylglucosamine PTS transporter activity" EXACT [] xref: GO:0022880 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002952 ! N-acetylglucosamine transmembrane transporter activity is_a: CCO:F0002954 ! trehalose transmembrane transporter activity [Term] id: CCO:F0004302 name: protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "N-acetylgalactosamine PTS transporter activity" EXACT [] xref: GO:0022881 is_a: CCO:F0001581 ! glucose transmembrane transporter activity is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002951 ! N-acetylgalactosamine transmembrane transporter activity [Term] id: CCO:F0004303 name: protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity namespace: molecular_function def: "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport." [GOC:mtg_transport, ISBN:0815340729] synonym: "beta-glucoside PTS transporter activity" EXACT [] xref: GO:0022882 is_a: CCO:F0002314 ! protein-N(PI)-phosphohistidine-sugar phosphotransferase activity is_a: CCO:F0002953 ! beta-glucoside transmembrane transporter activity [Term] id: CCO:F0004304 name: zinc efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane." [GOC:mtg_transport, ISBN:0815340729] synonym: "zinc efflux permease activity" EXACT [] xref: GO:0022883 is_a: CCO:F0006231 ! cation efflux transmembrane transporter activity [Term] id: CCO:F0004305 name: macromolecule transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a macromolecule from one side of the membrane to the other." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0022884 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0004306 name: bacteriocin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a bacteriocin from one side of the membrane to the other." [GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0022885 is_a: CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity [Term] id: CCO:F0004307 name: channel-forming ionophore activity namespace: molecular_function def: "Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive." [GOC:mtg_transport, ISBN:0815340729] synonym: "ionophore activity" BROAD [] xref: GO:0022886 is_a: CCO:F0002725 ! channel activity [Term] id: CCO:F0004308 name: serine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid." [GOC:mtg_transport, ISBN:0815340729] xref: GO:0022889 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0004309 name: inorganic cation transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0022890 is_a: CCO:F0001835 ! cation transmembrane transporter activity [Term] id: CCO:F0004310 name: substrate-specific transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a specific substance or group of related substances from one side of a membrane to the other." [GOC:jic, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0022891 is_a: CCO:F0004284 ! transmembrane transporter activity is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0004311 name: substrate-specific transporter activity namespace: molecular_function def: "Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells." [GOC:mtg_transport] subset: gosubset_prok xref: GO:0022892 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0004312 name: low-affinity tryptophan transmembrane transporter activity namespace: molecular_function def: "Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid." [GOC:mtg_transport, ISBN:0815340729] synonym: "low-affinity tryptophan permease activity" RELATED [] xref: GO:0015510 xref: GO:0022893 is_a: CCO:F0002670 ! L-tryptophan transmembrane transporter activity [Term] id: CCO:F0004313 name: Intermediate conductance calcium-activated potassium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, OMIM:602754] synonym: "IK calcium-activated potassium channel activity " EXACT [] synonym: "IK KCa channels" EXACT [] synonym: "intermdiate conductance KCa channels " EXACT [] xref: GO:0022894 is_a: CCO:F0002726 ! calcium-activated potassium channel activity [Term] id: CCO:F0004314 name: proton-dependent peptide secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement." [GOC:mtg_transport] subset: gosubset_prok synonym: "hydrogen/oligopeptide symporter" RELATED [] xref: GO:0022897 is_a: CCO:F0002671 ! peptide transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0004315 name: tryptase activity namespace: molecular_function def: "Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa, but with more restricted specificity than trypsin." [EC:3.4.21.59] subset: gosubset_prok synonym: "lung tryptase activity" NARROW [EC:3.4.21.59] synonym: "mast cell neutral proteinase activity" EXACT [EC:3.4.21.59] synonym: "mast cell protease II activity" NARROW [EC:3.4.21.59] synonym: "mast cell proteinase II" RELATED [EC:3.4.21.59] synonym: "mast cell serine proteinase II" RELATED [EC:3.4.21.59] synonym: "mast cell serine proteinase tryptase activity" EXACT [EC:3.4.21.59] synonym: "mast cell tryptase activity" NARROW [EC:3.4.21.59] synonym: "pituitary tryptase activity" NARROW [EC:3.4.21.59] synonym: "rat mast cell protease II" RELATED [EC:3.4.21.59] synonym: "skin tryptase activity" NARROW [EC:3.4.21.59] synonym: "tryptase M" RELATED [EC:3.4.21.59] xref: EC:3.4.21.59 xref: GO:0030019 xref: MetaCyc:3.4.21.59-RXN is_a: CCO:F0000720 ! trypsin activity [Term] id: CCO:F0004316 name: extracellular matrix structural constituent conferring tensile strength namespace: molecular_function def: "A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress." [GOC:mah, ISBN:0815316194] xref: GO:0030020 is_a: CCO:F0001487 ! extracellular matrix structural constituent [Term] id: CCO:F0004317 name: extracellular matrix structural constituent conferring compression resistance namespace: molecular_function def: "A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan." [GOC:mah, ISBN:0815316194] xref: GO:0030021 is_a: CCO:F0001487 ! extracellular matrix structural constituent [Term] id: CCO:F0004318 name: extracellular matrix constituent conferring elasticity namespace: molecular_function def: "A component of the extracellular matrix that enables the matrix to recoil after transient stretching." [GOC:mah, ISBN:0815316194] synonym: "elastin" RELATED [] xref: GO:0030023 is_a: CCO:F0001487 ! extracellular matrix structural constituent [Term] id: CCO:F0004319 name: amine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: R-CH2-NH2 + H2O + acceptor = R-CHO + NH3 + reduced acceptor." [EC:1.4.99.3] subset: gosubset_prok synonym: "amine: (acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.99.3] synonym: "MADH activity" EXACT [EC:1.4.99.3] synonym: "methylamine dehydrogenase activity" EXACT [EC:1.4.99.3] synonym: "primary-amine dehydrogenase activity" BROAD [EC:1.4.99.3] synonym: "primary-amine:(acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.99.3] synonym: "primary-amine:acceptor oxidoreductase (deaminating)" EXACT [EC:1.4.99.3] xref: EC:1.4.99.3 xref: GO:0030058 xref: MetaCyc:AMINE-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0058 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0004320 name: aralkylamine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: R-CH2-NH2 + H2O + acceptor = R-CHO + NH3 + reduced acceptor; acts on aromatic amines and, more slowly, on some long-chain aliphatic amines, but not on methylamine or ethylamine." [EC:1.4.99.4] synonym: "aralkylamine:(acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.99.4] synonym: "aralkylamine:acceptor oxidoreductase (deaminating)" EXACT [EC:1.4.99.4] synonym: "aromatic amine dehydrogenase activity" EXACT [EC:1.4.99.4] synonym: "dehydrogenase, arylamine" EXACT [EC:1.4.99.4] synonym: "tyramine dehydrogenase activity" EXACT [EC:1.4.99.4] xref: EC:1.4.99.4 xref: GO:0030059 xref: MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0004321 name: L-malate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+. Also oxidizes some other 2-hydroxydicarboxylic acids." [EC:1.1.1.37] subset: gosubset_prok synonym: "(S)-malate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.37] synonym: "L-malate-NAD+ oxidoreductase activity" EXACT [EC:1.1.1.37] synonym: "malate (NAD) dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "malic acid dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "malic dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "MDH" RELATED [EC:1.1.1.37] synonym: "NAD-dependent malate dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "NAD-dependent malic dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "NAD-L-malate dehydrogenase activity" EXACT [] synonym: "NAD-linked malate dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "NAD-malate dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "NAD-malic dehydrogenase activity" EXACT [EC:1.1.1.37] synonym: "NAD-specific malate dehydrogenase activity" EXACT [EC:1.1.1.37] xref: EC:1.1.1.37 xref: GO:0030060 xref: MetaCyc:MALATE-DEH-RXN xref: Reactome:19541 is_a: CCO:F0003217 ! malate dehydrogenase activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004322 name: HLA-A specific inhibitory MHC class I receptor activity namespace: molecular_function def: "Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] xref: GO:0030107 is_a: CCO:F0004980 ! inhibitory MHC class I receptor activity [Term] id: CCO:F0004323 name: HLA-A specific activating MHC class I receptor activity namespace: molecular_function def: "Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] xref: GO:0030108 is_a: CCO:F0004981 ! activating MHC class I receptor activity [Term] id: CCO:F0004324 name: HLA-B specific inhibitory MHC class I receptor activity namespace: molecular_function def: "Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] xref: GO:0030109 is_a: CCO:F0004980 ! inhibitory MHC class I receptor activity [Term] id: CCO:F0004325 name: HLA-C specific inhibitory MHC class I receptor activity namespace: molecular_function def: "Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, GOC:mah, PMID:11929129, PMID:9368779] xref: GO:0030110 is_a: CCO:F0004980 ! inhibitory MHC class I receptor activity [Term] id: CCO:F0004326 name: glial cell line-derived neurotrophic factor receptor binding namespace: molecular_function def: "A growth factor that binds to glial cell line-derived neurotrophic factor receptors." [PMID:11476867] synonym: "glial cell line-derived neurotrophic factor receptor ligand" NARROW [] xref: GO:0030116 is_a: CCO:F0001702 ! growth factor activity [Term] id: CCO:F0004327 name: alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors." [EC:2.4.1.155] synonym: "alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase activity" EXACT [] synonym: "alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] synonym: "GnTV activity" EXACT [EC:2.4.1.155] synonym: "N-acetylglucosaminyltransferase V activity" RELATED [EC:2.4.1.155] synonym: "UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.155] synonym: "UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] synonym: "UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] synonym: "uridine diphosphoacetylglucosamine-alpha-mannoside beta-1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] synonym: "uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.155] xref: EC:2.4.1.155 xref: GO:0030144 xref: MetaCyc:2.4.1.155-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0004328 name: manganese ion binding namespace: molecular_function def: "Interacting selectively with manganese (Mn) ions." [GOC:ai] subset: gosubset_prok synonym: "manganese binding" EXACT [] xref: GO:0030145 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0004329 name: molybdenum ion binding namespace: molecular_function def: "Interacting selectively with molybdenum (Mo) ions." [GOC:ai] subset: gosubset_prok synonym: "molybdenum binding" EXACT [] xref: GO:0030151 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0004330 name: benzodiazepine receptor binding namespace: molecular_function def: "Interacting selectively with the peripheral benzodiazepine receptor (PBR)." [GOC:ceb, GOC:mah, PMID:9915832] synonym: "benzodiazepine receptor ligand" NARROW [] synonym: "diazepam binding inhibitor activity" RELATED [] xref: GO:0030156 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0004331 name: protein xylosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate." [EC:2.4.2.26] synonym: "peptide O-xylosyltransferase activity" EXACT [] synonym: "UDP-D-xylose:core protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] synonym: "UDP-D-xylose:core protein xylosyltransferase activity" EXACT [EC:2.4.2.26] synonym: "UDP-D-xylose:protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] synonym: "UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] synonym: "UDP-xylose-core protein beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.26] synonym: "uridine diphosphoxylose-core protein beta-xylosyltransferase activity" EXACT [EC:2.4.2.26] synonym: "uridine diphosphoxylose-protein xylosyltransferase activity" EXACT [EC:2.4.2.26] xref: EC:2.4.2.26 xref: GO:0030158 xref: MetaCyc:2.4.2.26-RXN is_a: CCO:F0005581 ! UDP-xylosyltransferase activity [Term] id: CCO:F0004332 name: receptor signaling complex scaffold activity namespace: molecular_function def: "Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex." [GOC:mah] synonym: "receptor signaling complex scaffold protein activity" EXACT [] synonym: "receptor signalling complex scaffold activity" EXACT [] xref: GO:0030159 is_a: CCO:F0005052 ! protein complex scaffold [Term] id: CCO:F0004333 name: GKAP/Homer scaffold activity namespace: molecular_function def: "Functions as a physical support bridging the N-methyl-D-aspartate receptor-PSD-95-GKAP complex and the mGluR-Homer complex, which are involved in receptor signaling in synapses." [PMID:10506216] synonym: "GKAP/Homer scaffold protein" NARROW [] synonym: "postsynaptic density scaffold protein" NARROW [] xref: GO:0030160 is_a: CCO:F0004332 ! receptor signaling complex scaffold activity [Term] id: CCO:F0004334 name: calpain inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue." [GOC:ai] xref: GO:0030161 is_a: CCO:F0001224 ! cysteine protease inhibitor activity [Term] id: CCO:F0004335 name: PDZ domain binding namespace: molecular_function def: "Interacting selectively with a PDZ domain of a protein, a domain found in diverse signaling proteins." [GOC:go_curators, Pfam:PF00595] synonym: "DHR-domain binding" EXACT [] synonym: "GLGF-domain binding" EXACT [] xref: GO:0030165 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004336 name: low-density lipoprotein binding namespace: molecular_function def: "Interacting selectively with low-density lipoprotein, one of the classes of lipoproteins found in blood plasma in many animals (data normally relate to humans)." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "LDL binding" EXACT [] xref: GO:0030169 is_a: CCO:F0001687 ! lipoprotein binding [Term] id: CCO:F0004337 name: pyridoxal phosphate binding namespace: molecular_function def: "Interacting selectively with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "vitamin B6 binding" EXACT [] xref: GO:0030170 is_a: CCO:F0004191 ! vitamin binding is_a: CCO:F0007309 ! cofactor binding [Term] id: CCO:F0004338 name: voltage-gated proton channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of a proton by a voltage-gated channel." [ISBN:10615049] synonym: "voltage gated proton channel activity" EXACT [] synonym: "voltage-dependent proton channel activity" EXACT [] xref: GO:0030171 is_a: CCO:F0004274 ! voltage-gated cation channel activity [Term] id: CCO:F0004339 name: troponin C binding namespace: molecular_function def: "Interacting selectively with troponin C, the calcium-binding subunit of the troponin complex." [GOC:mah, ISBN:0815316194] xref: GO:0030172 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004340 name: nitric oxide transporter activity namespace: molecular_function def: "Enables the directed movement of nitric oxide, nitrogen monoxide, into, out of, within or between cells." [GOC:mah] subset: gosubset_prok xref: GO:0030184 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0004341 name: chaperone regulator activity namespace: molecular_function def: "Modulates the activity of a molecular chaperone." [GOC:mah] subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: gosubset_prok xref: GO:0030188 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0004342 name: chaperone activator activity namespace: molecular_function def: "Increases the activity of a molecular chaperone." [GOC:mah] subset: gosubset_prok xref: GO:0030189 is_a: CCO:F0004341 ! chaperone regulator activity [Term] id: CCO:F0004343 name: chaperone inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a molecular chaperone." [GOC:mah] xref: GO:0030190 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0004341 ! chaperone regulator activity [Term] id: CCO:F0004344 name: Hsp70/Hsc70 protein inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of chaperones of the Hsp70/Hsc70 class." [GOC:mah] xref: GO:0030191 is_a: CCO:F0004343 ! chaperone inhibitor activity is_a: CCO:F0004345 ! Hsp70/Hsc70 protein regulator activity [Term] id: CCO:F0004345 name: Hsp70/Hsc70 protein regulator activity namespace: molecular_function def: "Modulates the activity of chaperones of the Hsp70/Hsc70 class." [GOC:mah] subset: gosubset_prok xref: GO:0030192 is_a: CCO:F0004341 ! chaperone regulator activity [Term] id: CCO:F0004346 name: cyanide hydratase activity namespace: molecular_function def: "Catalysis of the reaction: formamide = cyanide + H2O." [EC:4.2.1.66] synonym: "formamide dehydratase activity" EXACT [EC:4.2.1.66] synonym: "formamide hydro-lyase (cyanide-forming)" EXACT [EC:4.2.1.66] synonym: "formamide hydro-lyase activity" EXACT [EC:4.2.1.66] xref: EC:4.2.1.66 xref: GO:0030196 xref: MetaCyc:CYANIDE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004347 name: extracellular matrix constituent, lubricant activity namespace: molecular_function def: "Functions as a lubricant for an extracellular matrix, such as a mucous membrane." [GOC:mah] xref: GO:0030197 is_a: CCO:F0001487 ! extracellular matrix structural constituent [Term] id: CCO:F0004348 name: semaphorin receptor binding namespace: molecular_function def: "Interacting selectively with semaphorin receptors." [GOC:ceb, PMID:12001990] synonym: "plexin binding" NARROW [] synonym: "plexin ligand" NARROW [] synonym: "semaphorin receptor ligand" NARROW [] xref: GO:0030215 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0004349 name: apolipoprotein receptor activity namespace: molecular_function def: "Combining with an apolipoprotein, the protein component of a lipoprotein, to initiate a change in cell activity." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030226 is_a: CCO:F0001226 ! receptor activity is_a: CCO:F0005523 ! apolipoprotein binding [Term] id: CCO:F0004350 name: apolipoprotein E receptor activity namespace: molecular_function def: "Combining with apolipoprotein E to initiate a change in cell activity." [GOC:mah] synonym: "ApoE receptor" EXACT [] xref: GO:0030227 is_a: CCO:F0004349 ! apolipoprotein receptor activity is_a: CCO:F0005525 ! apolipoprotein E binding [Term] id: CCO:F0004351 name: lipoprotein receptor activity namespace: molecular_function def: "Combining with a lipoprotein to initiate a change in cell activity. A lipoprotein is any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids; the lipid may be triacylglycerol, cholesterol, or phospholipid, or a combination of these." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0030228 is_a: CCO:F0001240 ! transmembrane receptor activity is_a: CCO:F0001687 ! lipoprotein binding [Term] id: CCO:F0004352 name: very-low-density lipoprotein receptor activity namespace: molecular_function def: "Combining with a very-low-density lipoprotein to initiate a change in cell activity." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "VLDL receptor" EXACT [] xref: GO:0030229 is_a: CCO:F0004351 ! lipoprotein receptor activity is_a: CCO:F0005527 ! very-low-density lipoprotein binding [Term] id: CCO:F0004353 name: deoxynucleotide transmembrane transporter activity namespace: molecular_function def: "Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP." [PMID:11226231] xref: GO:0030233 is_a: CCO:F0002686 ! nucleotide transmembrane transporter activity [Term] id: CCO:F0004354 name: enzyme regulator activity namespace: molecular_function def: "Modulates the activity of an enzyme." [GOC:mah] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "enzyme modulator" EXACT [] xref: GO:0030234 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0004355 name: nitric-oxide synthase regulator activity namespace: molecular_function def: "Modulates the activity of nitric oxide synthase." [GOC:mah] comment: See also 'regulation of nitric-oxide synthase activity ; GO:0050999'. synonym: "nitric oxide synthase regulator activity" EXACT [] xref: GO:0030235 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0004356 name: carbohydrate binding namespace: molecular_function def: "Interacting selectively with any carbohydrate." [GOC:mah] subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: gosubset_prok synonym: "selectin" RELATED [] xref: GO:0030246 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0004357 name: polysaccharide binding namespace: molecular_function def: "Interacting selectively with any polysaccharide." [GOC:mah] subset: gosubset_prok xref: GO:0030247 is_a: CCO:F0000239 ! pattern binding is_a: CCO:F0004356 ! carbohydrate binding [Term] id: CCO:F0004358 name: cellulose binding namespace: molecular_function def: "Interacting selectively with cellulose." [GOC:mah] subset: gosubset_prok xref: GO:0030248 is_a: CCO:F0004357 ! polysaccharide binding [Term] id: CCO:F0004359 name: guanylate cyclase regulator activity namespace: molecular_function def: "Modulates the activity of guanylate cyclase." [GOC:mah] xref: GO:0030249 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0004360 name: guanylate cyclase activator activity namespace: molecular_function def: "Increases the activity of guanylate cyclase." [GOC:mah] synonym: "guanylin" EXACT [] xref: GO:0030250 is_a: CCO:F0001691 ! enzyme activator activity is_a: CCO:F0004359 ! guanylate cyclase regulator activity [Term] id: CCO:F0004361 name: guanylate cyclase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of guanylate cyclase." [GOC:mah] xref: GO:0030251 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0004359 ! guanylate cyclase regulator activity [Term] id: CCO:F0004362 name: quinate 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: quinate + NAD+ = 5-dehydroquinate + NADH + H+." [EC:1.1.1.24] synonym: "quinate:NAD oxidoreductase activity" EXACT [EC:1.1.1.24] synonym: "quinate:NAD(+) 5-oxidoreductase activity" EXACT [EC:1.1.1.24] synonym: "quinic dehydrogenase activity" EXACT [EC:1.1.1.24] xref: EC:1.1.1.24 xref: GO:0030266 xref: MetaCyc:QUINATE-5-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004363 name: glyoxylate reductase (NADP) activity namespace: molecular_function def: "Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+." [EC:1.1.1.79] subset: gosubset_prok synonym: "glycolate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.79] synonym: "glyoxylate reductase (NADP+)" EXACT [EC:1.1.1.79] synonym: "NADPH-glyoxylate reductase activity" EXACT [EC:1.1.1.79] xref: EC:1.1.1.79 xref: GO:0030267 xref: MetaCyc:GLYOXYLATE-REDUCTASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004364 name: methylenetetrahydromethanopterin dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420." [EC:1.5.99.9] subset: gosubset_prok synonym: "5,10-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.5.99.9] synonym: "5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity" EXACT [EC:1.5.99.9] synonym: "N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.5.99.9] xref: EC:1.5.99.9 xref: GO:0018536 xref: GO:0030268 xref: MetaCyc:1.5.99.9-RXN xref: UM-BBD_enzymeID:e0124 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0004365 name: tetrahydromethanopterin S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate. 2-(methylthio)ethanesulfonate is also known as methyl-CoM." [EC:2.1.1.86] subset: gosubset_prok synonym: "5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase activity" EXACT [EC:2.1.1.86] synonym: "N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase activity" EXACT [EC:2.1.1.86] synonym: "N5-methyltetrahydromethanopterin--coenzyme M methyltransferase activity" EXACT [EC:2.1.1.86] synonym: "tetrahydromethanopterin methyltransferase activity" EXACT [EC:2.1.1.86] xref: EC:2.1.1.86 xref: GO:0018709 xref: GO:0030269 xref: MetaCyc:2.1.1.86-RXN xref: UM-BBD_enzymeID:e0145 is_a: CCO:F0001759 ! S-methyltransferase activity is_a: CCO:F0005622 ! 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity [Term] id: CCO:F0004366 name: formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran + N5-formyl-5,6,7,8-tetrahydromethanopterin." [EC:2.3.1.101] subset: gosubset_prok synonym: "formylmethanofuran-tetrahydromethanopterin formyltransferase activity" EXACT [EC:2.3.1.101] synonym: "formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase activity" EXACT [EC:2.3.1.101] synonym: "formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase activity" EXACT [EC:2.3.1.101] synonym: "formylmethanofuran:tetrahydromethanopterin formyltransferase activity" EXACT [EC:2.3.1.101] synonym: "FTR" RELATED [EC:2.3.1.101] synonym: "N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase activity" EXACT [EC:2.3.1.101] xref: EC:2.3.1.101 xref: GO:0018714 xref: GO:0030270 xref: MetaCyc:2.3.1.101-RXN xref: UM-BBD_enzymeID:e0143 is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0004367 name: chymase activity namespace: molecular_function def: "Catalysis of the preferential cleavage: Phe-Xaa > Tyr-Xaa > Trp-Xaa > Leu-Xaa." [EC:3.4.21.39] synonym: "mast cell protease I activity" NARROW [EC:3.4.21.39] synonym: "mast cell serine proteinase" NARROW [EC:3.4.21.39] synonym: "SK protease activity" EXACT [EC:3.4.21.39] synonym: "skeletal muscle (SK) protease activity" NARROW [EC:3.4.21.39] synonym: "skeletal muscle protease" NARROW [EC:3.4.21.39] synonym: "skin chymotryptic proteinase" NARROW [EC:3.4.21.39] xref: EC:3.4.21.39 xref: GO:0030271 xref: MetaCyc:3.4.21.39-RXN is_a: CCO:F0000698 ! serine-type endopeptidase activity [Term] id: CCO:F0004368 name: 5-formyltetrahydrofolate cyclo-ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate." [EC:6.3.3.2] subset: gosubset_prok synonym: "5,10-methenyltetrahydrofolate synthetase activity" EXACT [EC:6.3.3.2] synonym: "5-formyltetrahydrofolate cyclo-ligase (ADP-forming)" EXACT [EC:6.3.3.2] synonym: "5-formyltetrahydrofolate cyclodehydrase" BROAD [EC:6.3.3.2] synonym: "5-Formyltetrahydrofolate cyclodehydrase activity" EXACT [EC:6.3.3.2] synonym: "formyltetrahydrofolic cyclodehydrase activity" EXACT [EC:6.3.3.2] synonym: "methenyl-THF synthetase activity" EXACT [EC:6.3.3.2] xref: EC:6.3.3.2 xref: GO:0019006 xref: GO:0030272 xref: MetaCyc:5-FORMYL-THF-CYCLO-LIGASE-RXN is_a: CCO:F0003441 ! cyclo-ligase activity [Term] id: CCO:F0004369 name: melanin-concentrating hormone receptor activity namespace: molecular_function def: "Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity." [GOC:mah] synonym: "MCH receptor" EXACT [] xref: GO:0030273 is_a: CCO:F0003181 ! protein-hormone receptor activity [Term] id: CCO:F0004370 name: LIM domain binding namespace: molecular_function def: "Interacting selectively with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions." [GOC:go_curators, Pfam:PF00412] xref: GO:0030274 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004371 name: LRR domain binding namespace: molecular_function def: "Interacting selectively with a LRR domain (leucine rich repeats) of a protein." [GOC:go_curators, Pfam:PF00560] xref: GO:0030275 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004372 name: clathrin binding namespace: molecular_function def: "Interacting selectively with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles." [GOC:jl, GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030276 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004373 name: structural constituent of epidermis namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure." [GOC:mah] xref: GO:0030280 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0004374 name: structural constituent of cutaneous appendage namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers." [GOC:mah, ISBN:0878932437] xref: GO:0030281 is_a: CCO:F0004373 ! structural constituent of epidermis [Term] id: CCO:F0004375 name: 3(or 17)beta-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+." [EC:1.1.1.51] subset: gosubset_prok synonym: "17beta-hydroxy steroid dehydrogenase" EXACT [EC:1.1.1.51] synonym: "3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase" EXACT [EC:1.1.1.51] synonym: "3beta-hydroxy steroid dehydrogenase" EXACT [EC:1.1.1.51] synonym: "3beta-hydroxysteroid dehydrogenase" EXACT [EC:1.1.1.51] synonym: "beta-hydroxy steroid dehydrogenase" EXACT [EC:1.1.1.51] xref: EC:1.1.1.51 xref: GO:0030283 xref: MetaCyc:1.1.1.51-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004376 name: estrogen receptor activity namespace: molecular_function def: "Combining with estrogen to initiate a change in cell activity." [GOC:ai] comment: Note that this term represents a function and not a gene product. Consider also annotating to the molecular function term 'transcription regulator activity ; GO:0030528'. xref: GO:0030284 is_a: CCO:F0000295 ! steroid hormone receptor activity [Term] id: CCO:F0004377 name: sphingolipid activator protein activity namespace: molecular_function def: "Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "saposin" NARROW [] xref: GO:0030290 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0004378 name: protein serine/threonine kinase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a protein serine/threonine kinase." [GOC:mah] xref: GO:0030291 is_a: CCO:F0001216 ! protein kinase inhibitor activity [Term] id: CCO:F0004379 name: protein tyrosine kinase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a protein tyrosine kinase." [GOC:mah] xref: GO:0030292 is_a: CCO:F0001216 ! protein kinase inhibitor activity [Term] id: CCO:F0004380 name: transmembrane receptor protein tyrosine kinase inhibitor activity namespace: molecular_function xref: GO:0030293 is_a: CCO:F0004379 ! protein tyrosine kinase inhibitor activity is_a: CCO:F0004459 ! receptor inhibitor activity [Term] id: CCO:F0004381 name: receptor signaling protein tyrosine kinase inhibitor activity namespace: molecular_function synonym: "receptor signalling protein tyrosine kinase inhibitor activity" EXACT [] xref: GO:0030294 is_a: CCO:F0004379 ! protein tyrosine kinase inhibitor activity [Term] id: CCO:F0004382 name: protein kinase activator activity namespace: molecular_function def: "Increases the activity of a protein kinase, an enzyme which phosphorylates a protein." [GOC:ai] subset: gosubset_prok xref: GO:0030295 is_a: CCO:F0004132 ! kinase activator activity is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0004383 name: protein tyrosine kinase activator activity namespace: molecular_function def: "Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030296 is_a: CCO:F0004382 ! protein kinase activator activity [Term] id: CCO:F0004384 name: transmembrane receptor protein tyrosine kinase activator activity namespace: molecular_function xref: GO:0030297 is_a: CCO:F0004383 ! protein tyrosine kinase activator activity is_a: CCO:F0004458 ! receptor activator activity [Term] id: CCO:F0004385 name: receptor signaling protein tyrosine kinase activator activity namespace: molecular_function synonym: "receptor signalling protein tyrosine kinase activator activity" EXACT [] xref: GO:0030298 is_a: CCO:F0004383 ! protein tyrosine kinase activator activity [Term] id: CCO:F0004386 name: stromelysin 2 activity namespace: molecular_function def: "Catalysis of the cleavage of peptide bonds in collagen with preferential cleavage where P1', P2' and P3' are hydrophobic residues; action on collagen types III, IV and V is weak." [EC:3.4.24.17, EC:3.4.24.22] synonym: "matrix metalloproteinase 10 activity" EXACT [EC:3.4.24.22] synonym: "MMP-10" EXACT [] synonym: "proteoglycanase 2" RELATED [EC:3.4.24.22] synonym: "transin 2 activity" EXACT [EC:3.4.24.22] xref: EC:3.4.24.22 xref: GO:0030303 xref: MetaCyc:3.4.24.22-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0004387 name: trypsin inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the serine endopeptidase trypsin." [GOC:ai] subset: gosubset_prok xref: GO:0030304 is_a: CCO:F0001223 ! serine-type endopeptidase inhibitor activity [Term] id: CCO:F0004388 name: heparanase activity namespace: molecular_function def: "Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains." [PMID:10916150] synonym: "heparinase activity" RELATED [] xref: GO:0030305 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0004389 name: ADP-ribosylation factor binding namespace: molecular_function def: "Interacting selectively with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "ARF binding" EXACT [] xref: GO:0030306 is_a: CCO:F0004648 ! small GTPase binding [Term] id: CCO:F0004390 name: estrogen receptor binding namespace: molecular_function def: "Interacting selectively with an estrogen receptor." [GOC:ai] xref: GO:0030331 is_a: CCO:F0005586 ! steroid hormone receptor binding [Term] id: CCO:F0004391 name: cyclin binding namespace: molecular_function def: "Interacting selectively with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis." [GOC:ai] xref: GO:0030332 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004392 name: DNA polymerase processivity factor activity namespace: molecular_function def: "An accessory subunit of DNA polymerase that acts to increase the processivity of polymerization." [UniProtKB:P28958] subset: gosubset_prok synonym: "processivity clamp" EXACT [] synonym: "sliding clamp" EXACT [] xref: GO:0030337 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0004393 name: CMP-N-acetylneuraminate monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O." [EC:1.14.18.2] comment: Note that this was EC:1.14.13.45. synonym: "CMP-N-acetylneuraminate hydroxylase activity" EXACT [EC:1.14.18.2] synonym: "CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)" EXACT [EC:1.14.18.2] synonym: "CMP-N-acetylneuraminic acid hydroxylase activity" EXACT [] synonym: "CMP-Neu5Ac hydroxylase activity" EXACT [EC:1.14.18.2] synonym: "cytidine monophosphoacetylneuraminate monooxygenase activity" EXACT [EC:1.14.18.2] synonym: "cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity" EXACT [EC:1.14.18.2] synonym: "N-acetylneuraminic monooxygenase activity" EXACT [EC:1.14.18.2] xref: EC:1.14.18.2 xref: GO:0030338 xref: MetaCyc:1.14.13.45-RXN is_a: CCO:F0003299 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0004394 name: fatty-acyl-ethyl-ester synthase activity namespace: molecular_function def: "Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol." [EC:3.1.1.67] synonym: "FAEE synthase activity" EXACT [EC:3.1.1.67] synonym: "FAEES activity" EXACT [EC:3.1.1.67] synonym: "long-chain-fatty-acyl-ethyl-ester acylhydrolase activity" EXACT [EC:3.1.1.67] xref: EC:3.1.1.67 xref: GO:0030339 xref: MetaCyc:FATTY-ACYL-ETHYL-ESTER-SYNTHASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0004395 name: hyaluronate lyase activity namespace: molecular_function def: "Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine." [EC:4.2.2.1] subset: gosubset_prok synonym: "glucuronoglycosaminoglycan lyase activity" EXACT [EC:4.2.2.1] synonym: "hyaluronidase [but cf. EC 3.2.1.35 (hyalurononglucosaminidase) and EC 3.2.1.36 (hyaluronoglucuronidase)]" RELATED [EC:4.2.2.1] synonym: "hyaluronidase activity" BROAD [EC:4.2.2.1] synonym: "mucinase activity" EXACT [EC:4.2.2.1] synonym: "spreading factor activity" RELATED [EC:4.2.2.1] xref: EC:4.2.2.1 xref: GO:0030340 xref: MetaCyc:HYALURONATE-LYASE-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0004396 name: chondroitin AC lyase activity namespace: molecular_function def: "Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups." [EC:4.2.2.5] subset: gosubset_prok synonym: "ChnAC" RELATED [] synonym: "chondroitin AC eliminase activity" EXACT [EC:4.2.2.5] synonym: "chondroitin lyase activity" EXACT [] synonym: "chondroitin sulfate lyase activity" EXACT [EC:4.2.2.5] synonym: "chondroitinase AC" RELATED [] synonym: "chondroitinase activity" BROAD [] xref: EC:4.2.2.5 xref: GO:0030341 xref: MetaCyc:4.2.2.5-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0004397 name: 1-alpha,25-dihydroxyvitamin D3 (1,25-(OH)2D3) 24-hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of C-1 of 25-hydroxycalciferol (25-hydroxyvitamin D3) to form 1-alpha,25-dihydroxycalciferol." [ISBN:0471331309 "Biochemical Pathways"] xref: GO:0030342 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0004398 name: vitamin D3 25-hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of C-25 of calciferol (vitamin D3) to form 25-hydroxycalciferol." [ISBN:0471331309 "Biochemical Pathways"] synonym: "cholecalciferol 25-hydroxylase activity" EXACT [] xref: GO:0030343 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0004399 name: structural constituent of tooth enamel namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of tooth enamel." [GOC:mah] xref: GO:0030345 is_a: CCO:F0004317 ! extracellular matrix structural constituent conferring compression resistance [Term] id: CCO:F0004400 name: protein phosphatase 2B binding namespace: molecular_function def: "Interacting selectively with the enzyme protein phosphatase 2B." [GOC:jl] synonym: "calcineurin binding" EXACT [] xref: GO:0030346 is_a: CCO:F0004212 ! protein phosphatase binding [Term] id: CCO:F0004401 name: syntaxin-2 binding namespace: molecular_function def: "Interacting selectively with the SNAP receptor syntaxin-2." [GOC:ai] xref: GO:0030347 is_a: CCO:F0004214 ! syntaxin binding [Term] id: CCO:F0004402 name: syntaxin-3 binding namespace: molecular_function def: "Interacting selectively with the SNAP receptor syntaxin-3." [GOC:ai] xref: GO:0030348 is_a: CCO:F0004214 ! syntaxin binding [Term] id: CCO:F0004403 name: syntaxin-13 binding namespace: molecular_function def: "Interacting selectively with the SNAP receptor syntaxin-13." [GOC:ai] xref: GO:0030349 is_a: CCO:F0004214 ! syntaxin binding [Term] id: CCO:F0004404 name: iron-responsive element binding namespace: molecular_function def: "Interacting selectively with the iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins." [PMID:3198610, PMID:8710843] synonym: "IRE binding" EXACT [] xref: GO:0030350 is_a: CCO:F0000313 ! mRNA binding [Term] id: CCO:F0004405 name: inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate." [GOC:ai] xref: EC:3.1.3.- xref: GO:0030351 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0004406 name: inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate." [GOC:ai] xref: EC:3.1.3.- xref: GO:0030352 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0004407 name: fibroblast growth factor receptor antagonist activity namespace: molecular_function def: "Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist." [GOC:mah] synonym: "FGF receptor antagonist activity" EXACT [] synonym: "FGFR antagonist activity" EXACT [] xref: GO:0030353 is_a: CCO:F0001409 ! fibroblast growth factor receptor binding is_a: CCO:F0007301 ! receptor antagonist activity [Term] id: CCO:F0004408 name: melanin-concentrating hormone activity namespace: molecular_function xref: GO:0030354 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0004409 name: protein phosphatase type 2B regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme protein phosphatase type 2B." [GOC:ai] synonym: "protein phosphatase type 2B, intrinsic regulator activity" NARROW [] xref: GO:0030359 is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0004410 name: protein phosphatase type 4 regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme protein phosphatase type 4." [GOC:ai] synonym: "protein phosphatase type 4, intrinsic regulator activity" NARROW [] xref: GO:0030362 is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0004411 name: Mo-molybdopterin synthase activity namespace: molecular_function def: "Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis." [PMID:8514783] synonym: "molybdopterin synthase activity" EXACT [] xref: GO:0030366 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0004412 name: interleukin-17 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-17 receptor." [GOC:ai] synonym: "IL-17" NARROW [] synonym: "interleukin-17 receptor ligand" NARROW [] xref: GO:0030367 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0004413 name: interleukin-17 receptor activity namespace: molecular_function def: "Combining with interleukin-17 to initiate a change in cell activity." [GOC:jl] synonym: "IL-17R" EXACT [] xref: GO:0030368 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0004239 ! interleukin-17 binding [Term] id: CCO:F0004414 name: ICAM-3 receptor activity namespace: molecular_function def: "Combining with ICAM-3, intercellular adhesion molecule 3, to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'. xref: GO:0030369 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0004415 name: intercellular adhesion molecule-3 receptor binding namespace: molecular_function def: "Interacting selectively with receptors for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1." [GOC:ceb, PMID:11473836] synonym: "ICAM-3 receptor binding" EXACT [] synonym: "ICAM-3 receptor ligand" NARROW [] synonym: "intercellular adhesion molecule-3 receptor ligand" NARROW [] xref: GO:0030370 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0004416 name: translation repressor activity namespace: molecular_function def: "Antagonizes ribosome-mediated translation of mRNA into a polypeptide." [GOC:ai, GOC:clt] xref: GO:0030371 is_a: CCO:F0006094 ! translation regulator activity [Term] id: CCO:F0004417 name: high molecular weight B cell growth factor receptor binding namespace: molecular_function def: "Interacting selectively with the high molecular weight B cell growth factor receptor." [GOC:ai] synonym: "high molecular weight B cell growth factor receptor ligand" NARROW [] synonym: "high molecular weight B lymphocyte growth factor receptor binding" EXACT [] synonym: "high molecular weight B-cell growth factor receptor binding" EXACT [] synonym: "high molecular weight B-lymphocyte growth factor receptor binding" EXACT [] xref: GO:0030372 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0004418 name: high molecular weight B cell growth factor receptor activity namespace: molecular_function def: "Combining with a high molecular weight B cell growth factor to initiate a change in cell activity." [GOC:ai] synonym: "high molecular weight B lymphocyte growth factor receptor activity" EXACT [] synonym: "high molecular weight B-cell growth factor receptor activity" EXACT [] synonym: "high molecular weight B-lymphocyte growth factor receptor activity" EXACT [] xref: GO:0030373 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0004419 name: ligand-dependent nuclear receptor transcription coactivator activity namespace: molecular_function synonym: "ligand-dependent nuclear receptor transcription co-activator activity" EXACT [] xref: GO:0030374 is_a: CCO:F0000300 ! transcription coactivator activity [Term] id: CCO:F0004420 name: thyroid hormone receptor coactivator activity namespace: molecular_function synonym: "thyroid hormone receptor co-activator activity" EXACT [] xref: GO:0030375 is_a: CCO:F0004419 ! ligand-dependent nuclear receptor transcription coactivator activity [Term] id: CCO:F0004421 name: U-plasminogen activator receptor activity namespace: molecular_function synonym: "uPAR" EXACT [] synonym: "urokinase plasminogen activator receptor" EXACT [] xref: GO:0030377 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0004422 name: serine racemase activity namespace: molecular_function def: "Catalysis of the synthesis of free D-serine from L-serine." [GOC:kd] xref: GO:0030378 is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0004423 name: neurotensin receptor activity, non-G-protein coupled namespace: molecular_function synonym: "neurotensin receptor activity, non G protein coupled" EXACT [] synonym: "non G protein coupled neurotensin receptor activity" EXACT [] synonym: "non-G-protein coupled neurotensin receptor activity" EXACT [] synonym: "non-G-protein-coupled neurotensin receptor activity" EXACT [] xref: GO:0030379 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0004424 name: interleukin-17E receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-17E receptor." [GOC:ai] synonym: "IL-17E" NARROW [] synonym: "interleukin-17E receptor ligand" NARROW [] xref: GO:0030380 is_a: CCO:F0001428 ! hematopoietin/interferon-class (D200-domain) cytokine receptor binding [Term] id: CCO:F0004425 name: ferredoxin:thioredoxin reductase activity namespace: molecular_function def: "Catalysis of the two-electron reduction of the disulfide of thioredoxins with electrons from ferredoxin involving a 4Fe-4S cluster and an adjacent active-site disulfide." [PMID:14769790] xref: GO:0030385 is_a: CCO:F0003311 ! oxidoreductase activity, acting on iron-sulfur proteins as donors [Term] id: CCO:F0004426 name: fructosamine-3-kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation of fructosamine to form fructosamine-3-kinase." [PMID:11016445] xref: GO:0030387 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0004427 name: lactose binding namespace: molecular_function def: "Interacting selectively with lactose, a disaccharide of glucose and galactose, the carbohydrate of milk." [GOC:jl, ISBN:01928006X] xref: GO:0030395 is_a: CCO:F0007306 ! disaccharide binding [Term] id: CCO:F0004428 name: transcription antiterminator activity namespace: molecular_function def: "Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "transcriptional antiterminator activity" EXACT [] xref: GO:0030401 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0004429 name: matrilysin-2 activity namespace: molecular_function synonym: "matrix metalloproteinase 26" EXACT [] synonym: "MMP-26" EXACT [] xref: EC:3.4.24.- xref: GO:0030402 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0004430 name: collagenase 4 activity namespace: molecular_function synonym: "matrix metalloproteinase 18" EXACT [] synonym: "MMP-18" NARROW [] xref: GO:0030403 is_a: CCO:F0001737 ! collagenase activity [Term] id: CCO:F0004431 name: collagenase 3 activity namespace: molecular_function synonym: "matrix metalloproteinase 13" EXACT [] synonym: "MMP-13" EXACT [] xref: GO:0030404 is_a: CCO:F0001737 ! collagenase activity [Term] id: CCO:F0004432 name: matrix metalloproteinase 19 activity namespace: molecular_function synonym: "MMP-19" EXACT [] xref: GO:0030405 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0004433 name: matrix metalloproteinase 25 activity namespace: molecular_function synonym: "MMP-25" EXACT [] synonym: "MT6-MMP" EXACT [] xref: GO:0030406 is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0004434 name: formimidoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a formimino group from 5-formimidoyltetrahydrofolate to an acceptor molecule such as an amino acid." [EC:2.1.2.4, EC:2.1.2.5, GOC:mah] subset: gosubset_prok synonym: "formiminotransferase activity" EXACT [] xref: EC:2.1.2.- xref: GO:0030407 is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0004435 name: glycine formimidoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = tetrahydrofolate + N-formimidoylglycine." [EC:2.1.2.4] synonym: "5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase activity" EXACT [EC:2.1.2.4] synonym: "FIG formiminotransferase activity" EXACT [EC:2.1.2.4] synonym: "formiminoglycine formiminotransferase activity" EXACT [EC:2.1.2.4] synonym: "glycine formiminotransferase activity" EXACT [] xref: EC:2.1.2.4 xref: GO:0030408 xref: MetaCyc:GLYCINE-FORMIMINOTRANSFERASE-RXN is_a: CCO:F0004434 ! formimidoyltransferase activity [Term] id: CCO:F0004436 name: glutamate formimidoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate." [EC:2.1.2.5] subset: gosubset_prok synonym: "5-formimidoyltetrahydrofolate:L-glutamate N-formimidoyltransferase activity" EXACT [EC:2.1.2.5] synonym: "formiminoglutamic acid transferase activity" EXACT [EC:2.1.2.5] synonym: "formiminoglutamic formiminotransferase activity" EXACT [EC:2.1.2.5] synonym: "glutamate formiminotransferase activity" EXACT [] synonym: "glutamate formyltransferase activity" EXACT [EC:2.1.2.5] xref: EC:2.1.2.5 xref: GO:0030409 xref: MetaCyc:GLUTAMATE-FORMIMINOTRANSFERASE-RXN is_a: CCO:F0004434 ! formimidoyltransferase activity [Term] id: CCO:F0004437 name: nicotianamine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3 S-adenosyl-L-methionine = 3 5'-S-methyl-5'-thioadenosine + nicotianamine." [EC:2.5.1.43] subset: gosubset_prok synonym: "S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase activity" EXACT [EC:2.5.1.43] xref: EC:2.5.1.43 xref: GO:0030410 xref: MetaCyc:2.5.1.43-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0004438 name: scytalone dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H2O." [EC:4.2.1.94] synonym: "scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming)" EXACT [EC:4.2.1.94] synonym: "scytalone 7,8-hydro-lyase activity" EXACT [EC:4.2.1.94] xref: EC:4.2.1.94 xref: GO:0030411 xref: MetaCyc:SCYTALONE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0004439 name: formimidoyltetrahydrofolate cyclodeaminase activity namespace: molecular_function def: "Catalysis of the reaction: 5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH3." [EC:4.3.1.4] subset: gosubset_prok synonym: "5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)" EXACT [EC:4.3.1.4] synonym: "5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)" EXACT [EC:4.3.1.4] synonym: "formiminotetrahydrofolate cyclodeaminase activity" EXACT [EC:4.3.1.4] xref: EC:4.3.1.4 xref: GO:0030412 xref: MetaCyc:4.3.1.4-RXN xref: Reactome:23291 is_a: CCO:F0003406 ! ammonia-lyase activity is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0004440 name: competence pheromone activity namespace: molecular_function def: "A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence." [GOC:mah, PMID:7698645] subset: gosubset_prok xref: GO:0030413 is_a: CCO:F0001483 ! pheromone activity [Term] id: CCO:F0004441 name: protease inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a protease, any enzyme catalyzes the hydrolysis peptide bonds." [GOC:jl] subset: gosubset_prok synonym: "peptidase inhibitor" EXACT [] xref: GO:0030414 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0004442 name: carboxypeptidase A inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the enzyme carboxypeptidase A." [GOC:ai] xref: GO:0030415 is_a: CCO:F0004441 ! protease inhibitor activity [Term] id: CCO:F0004443 name: kynureninase activity namespace: molecular_function def: "Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine." [EC:3.7.1.3] subset: gosubset_prok synonym: "kynurenine hydrolase activity" EXACT [EC:3.7.1.3] synonym: "L-kynurenine hydrolase activity" EXACT [EC:3.7.1.3] synonym: "l-kynurenine hydrolase activity" EXACT [EC:3.7.1.3] xref: EC:3.7.1.3 xref: GO:0030429 xref: MetaCyc:KYNURENINASE-RXN xref: Reactome:23316 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0004444 name: inositol-4,5-bisphosphate 5-phosphatase activity namespace: molecular_function def: "Catalysis of the removal of a phosphate group from the carbon-5 position of D-myo-inositol 4,5-bisphosphate." [GOC:mah] xref: GO:0030487 is_a: CCO:F0003119 ! inositol bisphosphate phosphatase activity [Term] id: CCO:F0004445 name: hemoglobin binding namespace: molecular_function def: "Interacting selectively with hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:jl, http://cancerweb.ncl.ac.uk/] synonym: "globin binding" NARROW [] synonym: "haemoglobin binding" EXACT [] xref: GO:0030492 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004446 name: inorganic diphosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of inorganic diphosphate across a membrane." [PMID:11326272] synonym: "inorganic pyrophosphate transporter" EXACT [] xref: GO:0030504 is_a: CCO:F0002581 ! inorganic anion transmembrane transporter activity [Term] id: CCO:F0004447 name: ankyrin binding namespace: molecular_function def: "Interacting selectively with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030506 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004448 name: spectrin binding namespace: molecular_function def: "Interacting selectively with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030507 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004450 name: snoRNA binding namespace: molecular_function def: "Interacting selectively with small nucleolar RNA." [GOC:mah] xref: GO:0030515 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0004451 name: snoRNP binding namespace: molecular_function def: "Interacting selectively with a protein constituent of a small nucleolar ribonucleoprotein particle." [GOC:mah] xref: GO:0030519 is_a: CCO:F0005783 ! ribonucleoprotein binding [Term] id: CCO:F0004452 name: dihydrolipoamide S-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide." [EC:2.3.1.12, GOC:mah] subset: gosubset_prok xref: GO:0030523 is_a: CCO:F0003140 ! S-acyltransferase activity [Term] id: CCO:F0004453 name: structural constituent of chromatin namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of chromatin." [GOC:ai] xref: GO:0030527 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0004454 name: transcription regulator activity namespace: molecular_function def: "Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor." [GOC:mah] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "transcriptional regulator activity" EXACT [] xref: GO:0030528 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0004455 name: triplet codon-amino acid adaptor activity namespace: molecular_function def: "The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis." [GOC:hjd, GOC:mtg_MIT, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that this term can be used in place of the obsolete term 'transfer RNA ; GO:0005563'. subset: goslim_candida subset: goslim_generic subset: goslim_yeast synonym: "transfer RNA" RELATED [] synonym: "tRNA" RELATED [] xref: GO:0030533 is_a: CCO:F0000092 ! base pairing with mRNA is_a: CCO:F0008241 ! molecular adaptor activity [Term] id: CCO:F0004456 name: Hsp70 protein binding namespace: molecular_function def: "Interacting selectively with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0030544 is_a: CCO:F0004628 ! heat shock protein binding [Term] id: CCO:F0004457 name: receptor regulator activity namespace: molecular_function def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed." [GOC:ceb] xref: GO:0030545 is_a: CCO:F0001374 ! receptor signaling protein activity [Term] id: CCO:F0004458 name: receptor activator activity namespace: molecular_function def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased." [GOC:ceb] xref: GO:0030546 is_a: CCO:F0004457 ! receptor regulator activity [Term] id: CCO:F0004459 name: receptor inhibitor activity namespace: molecular_function def: "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased." [GOC:ceb] xref: GO:0030547 is_a: CCO:F0004457 ! receptor regulator activity [Term] id: CCO:F0004460 name: acetylcholine receptor regulator activity namespace: molecular_function def: "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed." [GOC:mah] xref: GO:0030548 is_a: CCO:F0004457 ! receptor regulator activity [Term] id: CCO:F0004461 name: acetylcholine receptor activator activity namespace: molecular_function def: "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased." [GOC:mah] xref: GO:0030549 is_a: CCO:F0004458 ! receptor activator activity is_a: CCO:F0004460 ! acetylcholine receptor regulator activity [Term] id: CCO:F0004462 name: acetylcholine receptor inhibitor activity namespace: molecular_function def: "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased." [GOC:mah] xref: GO:0030550 is_a: CCO:F0004459 ! receptor inhibitor activity is_a: CCO:F0004460 ! acetylcholine receptor regulator activity [Term] id: CCO:F0004463 name: cyclic nucleotide binding namespace: molecular_function def: "Interacting selectively with a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue." [GOC:ai] subset: gosubset_prok xref: GO:0030551 is_a: CCO:F0000031 ! nucleotide binding [Term] id: CCO:F0004464 name: cAMP binding namespace: molecular_function def: "Interacting selectively with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate)." [GOC:ai] subset: gosubset_prok synonym: "3',5' cAMP binding" EXACT [] synonym: "3',5'-cAMP binding" EXACT [] synonym: "adenosine 3',5'-cyclophosphate binding" EXACT [] synonym: "cyclic AMP binding" EXACT [] xref: GO:0030552 is_a: CCO:F0003068 ! AMP binding is_a: CCO:F0004463 ! cyclic nucleotide binding [Term] id: CCO:F0004465 name: cGMP binding namespace: molecular_function def: "Interacting selectively with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate)." [GOC:ai] synonym: "3',5' cGMP binding" EXACT [] synonym: "3',5'-cGMP binding" EXACT [] synonym: "cyclic GMP binding" EXACT [] xref: GO:0030553 is_a: CCO:F0004045 ! GMP binding is_a: CCO:F0004463 ! cyclic nucleotide binding [Term] id: CCO:F0004466 name: adenyl nucleotide binding namespace: molecular_function def: "Interacting selectively with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0030554 is_a: CCO:F0003548 ! purine nucleotide binding [Term] id: CCO:F0004467 name: RNA modification guide activity namespace: molecular_function def: "Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] synonym: "small nucleolar RNA" RELATED [] xref: GO:0030555 is_a: CCO:F0000091 ! base pairing with RNA [Term] id: CCO:F0004468 name: rRNA modification guide activity namespace: molecular_function def: "Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030556 is_a: CCO:F0000123 ! base pairing with rRNA is_a: CCO:F0004467 ! RNA modification guide activity [Term] id: CCO:F0004469 name: tRNA modification guide activity namespace: molecular_function def: "Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030557 is_a: CCO:F0000125 ! base pairing with tRNA is_a: CCO:F0004467 ! RNA modification guide activity [Term] id: CCO:F0004470 name: RNA pseudouridylation guide activity namespace: molecular_function def: "Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030558 is_a: CCO:F0004467 ! RNA modification guide activity [Term] id: CCO:F0004471 name: rRNA pseudouridylation guide activity namespace: molecular_function def: "Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030559 is_a: CCO:F0004468 ! rRNA modification guide activity is_a: CCO:F0004470 ! RNA pseudouridylation guide activity [Term] id: CCO:F0004472 name: tRNA pseudouridylation guide activity namespace: molecular_function def: "Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030560 is_a: CCO:F0004469 ! tRNA modification guide activity is_a: CCO:F0004470 ! RNA pseudouridylation guide activity [Term] id: CCO:F0004473 name: RNA 2'-O-ribose methylation guide activity namespace: molecular_function def: "Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030561 is_a: CCO:F0004467 ! RNA modification guide activity [Term] id: CCO:F0004474 name: rRNA 2'-O-ribose methylation guide activity namespace: molecular_function def: "Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030562 is_a: CCO:F0004468 ! rRNA modification guide activity is_a: CCO:F0004473 ! RNA 2'-O-ribose methylation guide activity [Term] id: CCO:F0004475 name: snRNA 2'-O-ribose methylation guide activity namespace: molecular_function def: "Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule." [PMID:11733745] comment: Note that this term may be useful for annotating snoRNAs. xref: GO:0030563 is_a: CCO:F0004473 ! RNA 2'-O-ribose methylation guide activity is_a: CCO:F0004478 ! snRNA modification guide activity [Term] id: CCO:F0004476 name: tRNA 2'-O-ribose methylation guide activity namespace: molecular_function def: "Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030564 is_a: CCO:F0004469 ! tRNA modification guide activity is_a: CCO:F0004473 ! RNA 2'-O-ribose methylation guide activity [Term] id: CCO:F0004477 name: snRNA pseudouridylation guide activity namespace: molecular_function def: "Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule." [PMID:11733745] comment: Note that this term may be useful for annotating snoRNAs. xref: GO:0030565 is_a: CCO:F0004470 ! RNA pseudouridylation guide activity is_a: CCO:F0004478 ! snRNA modification guide activity [Term] id: CCO:F0004478 name: snRNA modification guide activity namespace: molecular_function def: "Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue." [GOC:mah, PMID:12457565] xref: GO:0030566 is_a: CCO:F0000124 ! base pairing with snRNA is_a: CCO:F0004467 ! RNA modification guide activity [Term] id: CCO:F0004479 name: prothrombin activator activity namespace: molecular_function def: "Increases the rate of proteolysis catalyzed by thrombin." [GOC:mah] subset: gosubset_prok xref: GO:0030567 is_a: CCO:F0003185 ! protease activator activity [Term] id: CCO:F0004480 name: plasmin inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the serine endopeptidase plasmin." [GOC:mah] xref: GO:0030568 is_a: CCO:F0001223 ! serine-type endopeptidase inhibitor activity [Term] id: CCO:F0004481 name: chymotrypsin inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of the serine endopeptidase chymotrypsin." [GOC:mah] xref: GO:0030569 is_a: CCO:F0001223 ! serine-type endopeptidase inhibitor activity [Term] id: CCO:F0004482 name: pectate lyase activity namespace: molecular_function def: "Catalysis of the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends." [EC:4.2.2.2] subset: gosubset_prok synonym: "(1->4)-alpha-D-galacturonan lyase activity" EXACT [EC:4.2.2.2] synonym: "alpha-1,4-D-endopolygalacturonic acid lyase activity" EXACT [EC:4.2.2.2] synonym: "endo-alpha-1,4-polygalacturonic acid lyase activity" EXACT [EC:4.2.2.2] synonym: "endogalacturonate transeliminase activity" EXACT [EC:4.2.2.2] synonym: "endopectin methyltranseliminase activity" EXACT [EC:4.2.2.2] synonym: "pectate transeliminase activity" EXACT [EC:4.2.2.2] synonym: "pectic acid lyase activity" EXACT [EC:4.2.2.2] synonym: "pectic acid transeliminase activity" EXACT [EC:4.2.2.2] synonym: "pectic lyase activity" BROAD [EC:4.2.2.2] synonym: "pectin trans-eliminase activity" BROAD [EC:4.2.2.2] synonym: "PGA lyase activity" EXACT [EC:4.2.2.2] synonym: "polygalacturonate lyase activity" EXACT [EC:4.2.2.2] synonym: "polygalacturonic acid lyase activity" EXACT [EC:4.2.2.2] synonym: "polygalacturonic acid trans-eliminase activity" EXACT [EC:4.2.2.2] synonym: "polygalacturonic transeliminase activity" EXACT [EC:4.2.2.2] synonym: "PPase-N activity" EXACT [EC:4.2.2.2] xref: EC:4.2.2.2 xref: GO:0030570 xref: MetaCyc:4.2.2.2-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0004483 name: phosphatidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) moiety." [GOC:mb] subset: gosubset_prok xref: GO:0030572 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0004484 name: quinone cofactor methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1)." [GOC:mb] subset: gosubset_prok xref: GO:0030580 is_a: CCO:F0001756 ! C-methyltransferase activity [Term] id: CCO:F0004485 name: phosphoenolpyruvate carboxykinase (diphosphate) activity namespace: molecular_function def: "Catalysis of the reaction: diphosphate + oxaloacetate = phosphate + phosphoenolpyruvate + CO2." [EC:4.1.1.38] synonym: "diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)" EXACT [EC:4.1.1.38] synonym: "diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)" EXACT [EC:4.1.1.38] synonym: "PEP carboxyphosphotransferase activity" EXACT [EC:4.1.1.38] synonym: "PEPCTrP" RELATED [EC:4.1.1.38] synonym: "phosphoenolpyruvate carboxykinase (pyrophosphate) activity" EXACT [EC:4.1.1.38] synonym: "phosphoenolpyruvate carboxylase (pyrophosphate)" EXACT [EC:4.1.1.38] synonym: "phosphoenolpyruvate carboxyphosphotransferase activity" EXACT [EC:4.1.1.38] synonym: "phosphoenolpyruvate carboxytransphosphorylase activity" EXACT [EC:4.1.1.38] synonym: "phosphoenolpyruvic carboxykinase" BROAD [EC:4.1.1.38] synonym: "phosphoenolpyruvic carboxykinase (pyrophosphate)" EXACT [EC:4.1.1.38] synonym: "phosphoenolpyruvic carboxylase (pyrophosphate)" EXACT [EC:4.1.1.38] synonym: "phosphoenolpyruvic carboxytransphosphorylase activity" EXACT [EC:4.1.1.38] synonym: "phosphopyruvate carboxykinase" BROAD [EC:4.1.1.38] synonym: "phosphopyruvate carboxykinase (pyrophosphate)" EXACT [EC:4.1.1.38] synonym: "phosphopyruvate carboxylase (pyrophosphate)" EXACT [EC:4.1.1.38] xref: EC:4.1.1.38 xref: GO:0030585 xref: MetaCyc:4.1.1.38-RXN is_a: CCO:F0000990 ! phosphoenolpyruvate carboxykinase activity [Term] id: CCO:F0004487 name: NAD DNA ADP-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of the ADP-ribose moiety of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form." [PMID:11592983] xref: GO:0030591 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0004488 name: neurotransmitter receptor activity namespace: molecular_function def: "Combining with a neurotransmitter to initiate a change in cell activity." [GOC:jl] xref: GO:0030594 is_a: CCO:F0001226 ! receptor activity is_a: CCO:F0005633 ! neurotransmitter binding [Term] id: CCO:F0004489 name: alpha-L-rhamnosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides." [EC:3.2.1.40] subset: gosubset_prok synonym: "alpha-L-rhamnosidase N" RELATED [EC:3.2.1.40] synonym: "alpha-L-rhamnosidase T" RELATED [EC:3.2.1.40] synonym: "alpha-L-rhamnoside rhamnohydrolase activity" EXACT [EC:3.2.1.40] xref: EC:3.2.1.40 xref: GO:0030596 xref: MetaCyc:3.2.1.40-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0004490 name: RNA glycosylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule." [GOC:mah] subset: gosubset_prok xref: GO:0030597 is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0004491 name: rRNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species." [EC:3.2.2.22, GOC:mah] subset: gosubset_prok synonym: "gelonin" RELATED [EC:3.2.2.22] synonym: "mirabilis antiviral protein" RELATED [EC:3.2.2.22] synonym: "momorcochin-S" RELATED [EC:3.2.2.22] synonym: "nigrin b" RELATED [EC:3.2.2.22] synonym: "ribosomal ribonucleate N-glycosidase activity" EXACT [EC:3.2.2.22] synonym: "ricin" RELATED [EC:3.2.2.22] synonym: "RNA N-glycosidase activity" EXACT [EC:3.2.2.22] synonym: "rRNA N-glycohydrolase activity" EXACT [EC:3.2.2.22] synonym: "rRNA N-glycosidase activity" EXACT [] synonym: "saporins" RELATED [EC:3.2.2.22] xref: EC:3.2.2.22 xref: GO:0030598 xref: MetaCyc:3.2.2.22-RXN is_a: CCO:F0004490 ! RNA glycosylase activity [Term] id: CCO:F0004492 name: pectinesterase activity namespace: molecular_function def: "Catalysis of the reaction: pectin + n H2O = n methanol + pectate." [EC:3.1.1.11] subset: gosubset_prok synonym: "pectase activity" EXACT [EC:3.1.1.11] synonym: "pectin demethoxylase activity" EXACT [EC:3.1.1.11] synonym: "pectin methoxylase activity" EXACT [EC:3.1.1.11] synonym: "pectin methyl esterase activity" EXACT [EC:3.1.1.11] synonym: "pectin methylesterase activity" EXACT [] synonym: "pectin pectylhydrolase activity" EXACT [EC:3.1.1.11] synonym: "pectinoesterase activity" EXACT [EC:3.1.1.11] xref: EC:3.1.1.11 xref: GO:0030599 xref: MetaCyc:PECTINESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0004493 name: feruloyl esterase activity namespace: molecular_function def: "Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide." [EC:3.1.1.73] synonym: "4-hydroxy-3-methoxycinnamoyl-sugar hydrolase activity" EXACT [EC:3.1.1.73] synonym: "cinnAE" RELATED [EC:3.1.1.73] synonym: "cinnamoyl ester hydrolase activity" EXACT [] synonym: "FAE-I" RELATED [EC:3.1.1.73] synonym: "FAE-II" RELATED [EC:3.1.1.73] synonym: "FAE-III" RELATED [EC:3.1.1.73] synonym: "FAEA" RELATED [EC:3.1.1.73] synonym: "ferulic acid esterase activity" EXACT [EC:3.1.1.73] synonym: "hemicellulase accessory" RELATED [EC:3.1.1.73] synonym: "hydroxycinnamoyl esterase activity" EXACT [EC:3.1.1.73] xref: EC:3.1.1.73 xref: GO:0030600 xref: MetaCyc:3.1.1.73-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0004494 name: aminopeptidase B activity namespace: molecular_function def: "Catalysis of the release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys." [EC:3.4.11.6] synonym: "arginyl aminopeptidase activity" EXACT [] synonym: "arylamidase II" RELATED [EC:3.4.11.6] synonym: "Cl--activated arginine aminopeptidase activity" EXACT [EC:3.4.11.6] synonym: "cytosol aminopeptidase IV" RELATED [EC:3.4.11.6] synonym: "L-arginine aminopeptidase activity" EXACT [EC:3.4.11.6] xref: EC:3.4.11.6 xref: GO:0030601 xref: MetaCyc:3.4.11.6-RXN is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0004495 name: chymosin activity namespace: molecular_function def: "Catalysis of the lysis of peptide bonds with broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe-l-Met-Ala bond in kappa-casein." [EC:3.4.23.4] synonym: "rennin" RELATED [EC:3.4.23.4] synonym: "rennin (but this should be avoided since it leads to confusion with renin)" RELATED [EC:3.4.23.4] xref: EC:3.4.23.4 xref: GO:0030602 xref: MetaCyc:3.4.23.4-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0004496 name: oxaloacetase activity namespace: molecular_function def: "Catalysis of the reaction: oxaloacetate + H2O = oxalate + acetate." [EC:3.7.1.1] synonym: "oxalacetic hydrolase activity" EXACT [EC:3.7.1.1] synonym: "oxaloacetate acetylhydrolase activity" EXACT [EC:3.7.1.1] xref: EC:3.7.1.1 xref: GO:0030603 xref: MetaCyc:OXALOACETASE-RXN is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0004497 name: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH + H+; catalyzes the formation of 2-C-methyl-D-erythritol from 1-deoxy-D-xylulose-5-phosphate as the second step in the non-mevalonate pathway for terpenoid synthesis." [EC:1.1.1.267, GOC:mb] subset: gosubset_prok synonym: "1-deoxy-D-xylulose-5-phosphate isomeroreductase activity" EXACT [EC:1.1.1.267] synonym: "1-deoxyxylulose-5-phosphate reductoisomerase activity" EXACT [EC:1.1.1.267] synonym: "2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)" EXACT [EC:1.1.1.267] synonym: "2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity" EXACT [EC:1.1.1.267] synonym: "DOXP reductoisomerase activity" EXACT [] synonym: "DXP-reductoisomerase activity" EXACT [EC:1.1.1.267] xref: EC:1.1.1.267 xref: GO:0030604 xref: MetaCyc:DXPREDISOM-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004498 name: arsenate reductase activity namespace: molecular_function def: "Catalysis of the interconversion of arsenate and arsenite." [GOC:mah] subset: gosubset_prok xref: GO:0030611 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0004499 name: arsenate reductase (thioredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is NADPH -> thioredoxin reductase -> thioredoxin -> arsenate reductase." [GOC:kd] xref: GO:0030612 is_a: CCO:F0004498 ! arsenate reductase activity [Term] id: CCO:F0004500 name: oxidoreductase activity, acting on phosphorus or arsenic in donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor." [GOC:mah] comment: Note that enzymes of class EC:1.20.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors" NARROW [] xref: EC:1.20 xref: GO:0030613 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0004501 name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide." [GOC:mah] subset: gosubset_prok synonym: "oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor" EXACT [] xref: EC:1.20.4 xref: GO:0030614 is_a: CCO:F0004500 ! oxidoreductase activity, acting on phosphorus or arsenic in donors [Term] id: CCO:F0004502 name: transforming growth factor beta receptor, common-partner cytoplasmic mediator activity namespace: molecular_function def: "A TGFbeta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription." [GOC:hjd] comment: Note that this term can be used in place of the obsolete molecular function term 'common-partner SMAD protein ; GO:0005073' and is useful for annotating proteins of the SMAD family. synonym: "common-partner SMAD protein" RELATED [] synonym: "TGF-beta receptor, common-partner cytoplasmic mediator activity" EXACT [] synonym: "TGFbeta receptor, common-partner cytoplasmic mediator activity" EXACT [] xref: GO:0030616 is_a: CCO:F0001382 ! transforming growth factor beta receptor, cytoplasmic mediator activity [Term] id: CCO:F0004503 name: transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity namespace: molecular_function def: "A TGFbeta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators." [PMID:9759503] comment: Note that this term can be used in place of the obsolete molecular function term 'inhibitory SMAD protein ; GO:0005074' and is useful for annotating proteins of the SMAD family. synonym: "inhibitory SMAD protein" RELATED [] synonym: "TGF-beta receptor, inhibitory cytoplasmic mediator activity" EXACT [] synonym: "TGFbeta receptor, inhibitory cytoplasmic mediator activity" EXACT [] xref: GO:0030617 is_a: CCO:F0001382 ! transforming growth factor beta receptor, cytoplasmic mediator activity [Term] id: CCO:F0004504 name: transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity namespace: molecular_function def: "A TGFbeta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The heterocomplex translocates to the nucleus to regulate transcription." [GOC:hjd] comment: Note that this term can be used in place of the obsolete molecular function term 'pathway-specific SMAD protein ; GO:0005075' and is useful for annotating proteins of the SMAD family. synonym: "pathway-specific SMAD protein" NARROW [] synonym: "TGF-beta receptor, pathway-specific cytoplasmic mediator activity" EXACT [] synonym: "TGFbeta receptor, pathway-specific cytoplasmic mediator activity" EXACT [] xref: GO:0030618 is_a: CCO:F0001382 ! transforming growth factor beta receptor, cytoplasmic mediator activity [Term] id: CCO:F0004505 name: U1 snRNA binding namespace: molecular_function def: "Interacting selectively with the U1 small nuclear RNA (U1 snRNA)." [GOC:mah] comment: Note that this term may be useful for annotating other small nuclear RNAs (snRNAs). xref: GO:0030619 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004506 name: U2 snRNA binding namespace: molecular_function def: "Interacting selectively with the U2 small nuclear RNA (U2 snRNA)." [GOC:jl] xref: GO:0030620 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004507 name: U4 snRNA binding namespace: molecular_function def: "Interacting selectively with the U4 small nuclear RNA (U4 snRNA)." [GOC:jl] xref: GO:0030621 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004508 name: U4atac snRNA binding namespace: molecular_function def: "Interacting selectively with the U4atac small nuclear RNA (U4atac snRNA)." [GOC:jl] xref: GO:0030622 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004509 name: U5 snRNA binding namespace: molecular_function def: "Interacting selectively with the U5 small nuclear RNA (U5 snRNA)." [GOC:jl] xref: GO:0030623 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004510 name: U6atac snRNA binding namespace: molecular_function def: "Interacting selectively with the U6atac small nuclear RNA (U6atac snRNA)." [GOC:jl] xref: GO:0030624 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004511 name: U11 snRNA binding namespace: molecular_function def: "Interacting selectively with the U11 small nuclear RNA (U11 snRNA)." [GOC:jl] xref: GO:0030625 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004512 name: U12 snRNA binding namespace: molecular_function def: "Interacting selectively with the U12 small nuclear RNA (U12 snRNA)." [GOC:jl] xref: GO:0030626 is_a: CCO:F0003544 ! snRNA binding [Term] id: CCO:F0004513 name: pre-mRNA 5'-splice site binding namespace: molecular_function def: "Interacting selectively with the pre-mRNA 5' splice site sequence." [GOC:jl] synonym: "pre-mRNA 5' splice site binding" EXACT [] xref: GO:0030627 is_a: CCO:F0000313 ! mRNA binding is_a: CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism [Term] id: CCO:F0004514 name: pre-mRNA 3'-splice site binding namespace: molecular_function def: "Interacting selectively with the pre-mRNA 3' splice site sequence." [GOC:jl] synonym: "pre-mRNA 3' splice site binding" EXACT [] xref: GO:0030628 is_a: CCO:F0000313 ! mRNA binding is_a: CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism [Term] id: CCO:F0004515 name: U6 snRNA 3'-end binding namespace: molecular_function def: "Interacting selectively with the 3' end of the U6 small nuclear RNA (U6 snRNA)." [GOC:mah] comment: Note that this term may be useful for annotating small nuclear RNAs (snRNAs). synonym: "U6 snRNA 3' end binding" EXACT [] xref: GO:0030629 is_a: CCO:F0003545 ! U6 snRNA binding [Term] id: CCO:F0004516 name: protein binding, bridging namespace: molecular_function def: "Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other." [GOC:mah] subset: gosubset_prok synonym: "protein-protein adaptor" RELATED [] xref: GO:0030674 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004517 name: Rac GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by a GTPase of the Rac family." [GOC:mah] xref: GO:0030675 is_a: CCO:F0001405 ! Rho GTPase activator activity [Term] id: CCO:F0004518 name: Rac guanyl-nucleotide exchange factor activity namespace: molecular_function def: "Stimulates the exchange of guanyl nucleotides by a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] xref: GO:0030676 is_a: CCO:F0001394 ! Rho guanyl-nucleotide exchange factor activity [Term] id: CCO:F0004519 name: caspase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue." [PMID:10872455] synonym: "caspase-1 activity" NARROW [] synonym: "caspase-10 activity" NARROW [] synonym: "caspase-2 activity" NARROW [] synonym: "caspase-3 activity" NARROW [] synonym: "caspase-4 activity" NARROW [] synonym: "caspase-5 activity" NARROW [] synonym: "caspase-6 activity" NARROW [] synonym: "caspase-7 activity" NARROW [] synonym: "caspase-8 activity" NARROW [] synonym: "caspase-9 activity" NARROW [] synonym: "effector caspase activity" NARROW [] synonym: "signaling (initiator) caspase activity" NARROW [] xref: GO:0004199 xref: GO:0030693 xref: Reactome:82077 is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0004520 name: GTPase regulator activity namespace: molecular_function def: "Modulates the rate of GTP hydrolysis by a GTPase." [GOC:mah] subset: gosubset_prok xref: GO:0030695 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0004521 name: tRNA (m5U54) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule." [ISBN:1555811337 "Modification and Editing of RNA"] comment: Note that the term name mentions a specific position within a tRNA because no other names have yet arisen for this activity, and because the position is conserved in nearly all tRNAs. The term nevertheless can be used for activities that methylase an analogous residue at a position other than 54, if such is found, and synonyms that mention positions applicable to other tRNAs or species may also be added. synonym: "RUMT" EXACT [] xref: GO:0030696 is_a: CCO:F0003113 ! tRNA (uracil) methyltransferase activity [Term] id: CCO:F0004522 name: S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the C5 atom of the uridine residue at position 54 in a tRNA molecule." [ISBN:1555811337 "Modification and Editing of RNA"] synonym: "RUMT" BROAD [] synonym: "S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity" EXACT [] xref: GO:0030697 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity is_a: CCO:F0004521 ! tRNA (m5U54) methyltransferase activity [Term] id: CCO:F0004523 name: 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule." [ISBN:1555811337 "Modification and Editing of RNA"] synonym: "RUMT" BROAD [] xref: GO:0030698 is_a: CCO:F0004521 ! tRNA (m5U54) methyltransferase activity is_a: CCO:F0005619 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity [Term] id: CCO:F0004524 name: glycine reductase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl phosphate + ammonia + thioredoxin disulfide = glycine + phosphate + thioredoxin." [EC:1.21.4.2] subset: gosubset_prok synonym: "acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming)" EXACT [EC:1.21.4.2] xref: EC:1.21.4.2 xref: GO:0030699 is_a: CCO:F0007826 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor [Term] id: CCO:F0004525 name: NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]." [EC:2.4.2.37] subset: gosubset_prok synonym: "ADP-ribosyltransferase activity" BROAD [EC:2.4.2.37] synonym: "NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity" EXACT [EC:2.4.2.37] synonym: "NAD--azoferredoxin (ADP-ribose)transferase activity" EXACT [EC:2.4.2.37] synonym: "NAD-azoferredoxin (ADPribose)transferase activity" EXACT [EC:2.4.2.37] synonym: "NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity" EXACT [] xref: EC:2.4.2.37 xref: GO:0030701 xref: MetaCyc:2.4.2.37-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0004526 name: acetoacetate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA." [EC:6.2.1.16] subset: gosubset_prok synonym: "acetoacetate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.16] synonym: "acetoacetyl-CoA synthetase activity" EXACT [] xref: EC:6.2.1.16 xref: GO:0030729 xref: MetaCyc:ACETOACETATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0004527 name: guanidinoacetate N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine." [EC:2.1.1.2] synonym: "GA methylpherase activity" EXACT [EC:2.1.1.2] synonym: "guanidinoacetate methyltransferase activity" EXACT [EC:2.1.1.2] synonym: "guanidinoacetate transmethylase activity" EXACT [EC:2.1.1.2] synonym: "guanidoacetate methyltransferase activity" EXACT [EC:2.1.1.2] synonym: "methionine-guanidinoacetic transmethylase activity" EXACT [EC:2.1.1.2] synonym: "S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase activity" EXACT [EC:2.1.1.2] xref: EC:2.1.1.2 xref: GO:0030731 xref: MetaCyc:GUANIDINOACETATE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004528 name: methionine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine." [EC:2.1.1.12] synonym: "methionine methyltransferase activity" EXACT [EC:2.1.1.12] synonym: "S-adenosyl methionine:methionine methyl transferase activity" EXACT [EC:2.1.1.12] synonym: "S-adenosyl-L-methionine:L-methionine S-methyltransferase activity" EXACT [EC:2.1.1.12] synonym: "S-adenosylmethionine transmethylase activity" EXACT [EC:2.1.1.12] synonym: "S-adenosylmethionine-methionine methyltransferase activity" EXACT [EC:2.1.1.12] xref: EC:2.1.1.12 xref: GO:0030732 xref: MetaCyc:METHIONINE-S-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004529 name: fatty-acid O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester." [EC:2.1.1.15] synonym: "fatty acid methyltransferase activity" EXACT [EC:2.1.1.15] synonym: "fatty acid O-methyltransferase activity" EXACT [EC:2.1.1.15] synonym: "S-adenosyl-L-methionine:fatty-acid O-methyltransferase activity" EXACT [EC:2.1.1.15] xref: EC:2.1.1.15 xref: GO:0030733 xref: MetaCyc:FATTY-ACID-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004530 name: polysaccharide O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units." [EC:2.1.1.18] synonym: "acylpolysacharide 6-methyltransferase activity" EXACT [EC:2.1.1.18] synonym: "polysaccharide methyltransferase activity" EXACT [EC:2.1.1.18] synonym: "S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase activity" EXACT [EC:2.1.1.18] xref: EC:2.1.1.18 xref: GO:0030734 xref: MetaCyc:POLYSACCHARIDE-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004531 name: carnosine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine." [EC:2.1.1.22] synonym: "S-adenosyl-L-methionine:carnosine N-methyltransferase activity" EXACT [EC:2.1.1.22] xref: EC:2.1.1.22 xref: GO:0030735 xref: MetaCyc:CARNOSINE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004532 name: phenol O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole." [EC:2.1.1.25] synonym: "PMT" RELATED [EC:2.1.1.25] synonym: "S-adenosyl-L-methionine:phenol O-methyltransferase activity" EXACT [EC:2.1.1.25] xref: EC:2.1.1.25 xref: GO:0030736 xref: MetaCyc:PHENOL-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004533 name: iodophenol O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 2-iodophenol = S-adenosyl-L-homocysteine + 2-iodophenol methyl ether." [EC:2.1.1.26] synonym: "S-adenosyl-L-methionine:2-iodophenol O-methyltransferase activity" EXACT [EC:2.1.1.26] xref: EC:2.1.1.26 xref: GO:0030737 xref: MetaCyc:IODOPHENOL-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004534 name: tyramine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = S-adenosyl-L-homocysteine + N-methyltyramine." [EC:2.1.1.27] synonym: "DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)" EXACT [EC:2.1.1.27] synonym: "S-adenosyl-L-methionine:tyramine N-methyltransferase activity" EXACT [EC:2.1.1.27] synonym: "S-adenosyl-methionine:tyramine N-methyltransferase activity" EXACT [EC:2.1.1.27] synonym: "tyramine methylpherase activity" EXACT [EC:2.1.1.27] xref: EC:2.1.1.27 xref: GO:0030738 xref: MetaCyc:TYRAMINE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004535 name: O-demethylpuromycin O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin." [EC:2.1.1.38] subset: gosubset_prok synonym: "O-demethylpuromycin methyltransferase activity" EXACT [EC:2.1.1.38] synonym: "S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase activity" EXACT [EC:2.1.1.38] xref: EC:2.1.1.38 xref: GO:0030739 xref: MetaCyc:2.1.1.38-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004536 name: inositol 3-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-3-O-methyl-myo-inositol." [EC:2.1.1.39] synonym: "inositol L-1-methyltransferase activity" EXACT [EC:2.1.1.39] synonym: "myo-inositol 1-methyltransferase activity" RELATED [EC:2.1.1.39] synonym: "myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)" EXACT [EC:2.1.1.39] synonym: "myo-inositol 1-O-methyltransferase activity" RELATED [EC:2.1.1.39] synonym: "S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase activity" EXACT [EC:2.1.1.39] synonym: "S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase activity" EXACT [EC:2.1.1.39] synonym: "S-adenosylmethionine:myo-inositol 1-methyltransferase activity" EXACT [EC:2.1.1.39] xref: EC:2.1.1.39 xref: GO:0030740 xref: MetaCyc:MYO-INOSITOL-1-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004537 name: inositol 1-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 1D-1-O-methyl-myo-inositol." [EC:2.1.1.40] synonym: "inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)" EXACT [EC:2.1.1.40] synonym: "inositol 3-O-methyltransferase activity" RELATED [EC:2.1.1.40] synonym: "inositol D-1-methyltransferase activity" EXACT [EC:2.1.1.40] synonym: "myo-inositol 3-O-methyltransferase activity" RELATED [EC:2.1.1.40] synonym: "S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase activity" EXACT [EC:2.1.1.40] synonym: "S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase activity" EXACT [EC:2.1.1.40] synonym: "S-adenosylmethionine:myo-inositol 3-methyltransferase activity" RELATED [EC:2.1.1.40] xref: EC:2.1.1.40 xref: GO:0030741 xref: MetaCyc:MYO-INOSITOL-3-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004538 name: GTP-dependent protein binding namespace: molecular_function def: "Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP." [GOC:go_curators] xref: GO:0030742 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004539 name: rRNA (adenosine-2'-O-)-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine." [EC:2.1.1.66] subset: gosubset_prok synonym: "ribosomal ribonucleate adenosine 2'-methyltransferase activity" EXACT [EC:2.1.1.66] synonym: "RNA-pentose methylase activity" RELATED [EC:2.1.1.66] synonym: "rRNA adenosine 2'-methylase activity" EXACT [EC:2.1.1.66] synonym: "S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity" EXACT [EC:2.1.1.66] synonym: "thiostrepton-resistance methylase activity" NARROW [EC:2.1.1.66] xref: EC:2.1.1.66 xref: GO:0030743 xref: MetaCyc:2.1.1.66-RXN is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0003155 ! rRNA (adenine) methyltransferase activity [Term] id: CCO:F0004540 name: luteolin O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,3',4'-tetrahydroxyflavone = S-adenosyl-L-homocysteine + 5,7,4'-trihydroxy-3'-methoxyflavone." [EC:2.1.1.42] synonym: "luteolin 3'-O-methyltransferase activity" EXACT [EC:2.1.1.42] synonym: "luteolin methyltransferase activity" EXACT [EC:2.1.1.42] synonym: "o-dihydric phenol meta-O-methyltransferase activity" EXACT [EC:2.1.1.42] synonym: "o-dihydric phenol methyltransferase activity" EXACT [EC:2.1.1.42] synonym: "o-diphenol m-O-methyltransferase activity" EXACT [EC:2.1.1.42] synonym: "S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase activity" EXACT [EC:2.1.1.42] synonym: "S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase activity" EXACT [EC:2.1.1.42] xref: EC:2.1.1.42 xref: GO:0030744 xref: MetaCyc:LUTEOLIN-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004541 name: dimethylhistidine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + NN1,NN1-dimethyl-L-histidine = S-adenosyl-L-homocysteine + NN1,NN1,NN1-trimethyl-L-histidine." [EC:2.1.1.44] synonym: "dimethylhistidine methyltransferase activity" EXACT [EC:2.1.1.44] synonym: "histidine-alpha-N-methyltransferase activity" EXACT [EC:2.1.1.44] synonym: "S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity" EXACT [EC:2.1.1.44] synonym: "S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine nalpha-methyltransferase activity" EXACT [EC:2.1.1.44] xref: EC:2.1.1.44 xref: GO:0030745 xref: MetaCyc:2.1.1.44-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004542 name: isoflavone 4'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone." [EC:2.1.1.46] synonym: "4'-hydroxyisoflavone methyltransferase activity" EXACT [EC:2.1.1.46] synonym: "isoflavone methyltransferase activity" EXACT [EC:2.1.1.46] synonym: "isoflavone O-methyltransferase activity" EXACT [EC:2.1.1.46] synonym: "S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.46] xref: EC:2.1.1.46 xref: GO:0030746 xref: MetaCyc:ISOFLAVONE-4 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004543 name: indolepyruvate C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate." [EC:2.1.1.47] synonym: "indolepyruvate 3-methyltransferase activity" EXACT [EC:2.1.1.47] synonym: "indolepyruvate methyltransferase activity" EXACT [EC:2.1.1.47] synonym: "indolepyruvic acid methyltransferase activity" EXACT [EC:2.1.1.47] synonym: "S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase activity" EXACT [EC:2.1.1.47] synonym: "S-adenosyl-L-methionine:indolepyruvate C-methyltransferase activity" EXACT [EC:2.1.1.47] xref: EC:2.1.1.47 xref: GO:0030747 xref: MetaCyc:INDOLEPYRUVATE-C-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004544 name: amine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine." [EC:2.1.1.49] synonym: "arylamine N-methyltransferase activity" NARROW [EC:2.1.1.49] synonym: "nicotine N-methyltransferase activity" NARROW [EC:2.1.1.49] synonym: "S-adenosyl-L-methionine:amine N-methyltransferase activity" EXACT [EC:2.1.1.49] synonym: "tryptamine methyltransferase" NARROW [EC:2.1.1.49] synonym: "tryptamine N-methyltransferase activity" NARROW [EC:2.1.1.49] xref: EC:2.1.1.49 xref: GO:0030748 xref: MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004545 name: loganate O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin." [EC:2.1.1.50] synonym: "loganate methyltransferase activity" EXACT [EC:2.1.1.50] synonym: "S-adenosyl-L-methionine:loganate 11-O-methyltransferase activity" EXACT [EC:2.1.1.50] synonym: "S-adenosyl-L-methionine:loganic acid methyltransferase activity" EXACT [EC:2.1.1.50] xref: EC:2.1.1.50 xref: GO:0030749 xref: MetaCyc:LOGANATE-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004546 name: putrescine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = S-adenosyl-L-homocysteine + N-methylputrescine." [EC:2.1.1.53] synonym: "putrescine methyltransferase activity" EXACT [EC:2.1.1.53] synonym: "S-adenosyl-L-methionine:putrescine N-methyltransferase activity" EXACT [EC:2.1.1.53] xref: EC:2.1.1.53 xref: GO:0030750 xref: MetaCyc:PUTRESCINE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004547 name: licodione 2'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + licodione = S-adenosyl-L-homocysteine + 2'-O-methyllicodione." [EC:2.1.1.65] synonym: "S-adenosyl-L-methionine:licodione 2'-O-methyltransferase activity" EXACT [EC:2.1.1.65] xref: EC:2.1.1.65 xref: GO:0030751 xref: MetaCyc:LICODIONE-2 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004548 name: 5-hydroxyfuranocoumarin 5-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin." [EC:2.1.1.69] synonym: "bergaptol 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "bergaptol methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "bergaptol O-methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "BMT activity" EXACT [EC:2.1.1.69] synonym: "furanocoumarin 5-methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "furanocoumarin 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "S-adenosyl-L-methionine:bergaptol O-methyltransferase activity" EXACT [EC:2.1.1.69] synonym: "S-adenosyl-L-methionine:bergaptolO-methyltransferase activity" EXACT [EC:2.1.1.69] xref: EC:2.1.1.69 xref: GO:0030752 xref: GO:0030764 xref: MetaCyc:2.1.1.69-RXN xref: MetaCyc:BERGAPTOL-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004549 name: 8-hydroxyfuranocoumarin 8-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 8-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 8-methoxyfuranocoumarin." [EC:2.1.1.70] synonym: "furanocoumarin 8-methyltransferase activity" EXACT [EC:2.1.1.70] synonym: "furanocoumarin 8-O-methyl-transferase activity" EXACT [EC:2.1.1.70] synonym: "S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity" EXACT [EC:2.1.1.70] synonym: "S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase activity" EXACT [EC:2.1.1.70] synonym: "xanthotoxol 8-O-methyltransferase activity" EXACT [EC:2.1.1.70] synonym: "XMT activity" RELATED [EC:2.1.1.70] xref: EC:2.1.1.70 xref: GO:0030753 xref: MetaCyc:2.1.1.70-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004550 name: apigenin 4'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone." [EC:2.1.1.75] synonym: "flavonoid methyltransferase activity" EXACT [EC:2.1.1.75] synonym: "flavonoid O-methyltransferase activity" BROAD [EC:2.1.1.75] synonym: "S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.75] xref: EC:2.1.1.75 xref: GO:0030754 xref: MetaCyc:APIGENIN-4 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004551 name: quercetin 3-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone." [EC:2.1.1.76] synonym: "flavonoid 3-methyltransferase activity" EXACT [EC:2.1.1.76] synonym: "flavonol 3-O-methyltransferase activity" RELATED [EC:2.1.1.76] synonym: "S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase activity" EXACT [EC:2.1.1.76] xref: EC:2.1.1.76 xref: GO:0030755 xref: MetaCyc:QUERCETIN-3-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004552 name: isoorientin 3'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + isoorientin = S-adenosyl-L-homocysteine + isoscoparin." [EC:2.1.1.78] synonym: "isoorientin 3'-methyltransferase activity" EXACT [EC:2.1.1.78] synonym: "S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase activity" EXACT [EC:2.1.1.78] xref: EC:2.1.1.78 xref: GO:0030756 xref: MetaCyc:ISOORIENTIN-3 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004553 name: 3-methylquercitin 7-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3',4',5,7-tetrahydroxy-3-methoxyflavone = S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,7-dimethoxy-flavone." [EC:2.1.1.82] synonym: "3-methylquercetin 7-O-methyltransferase activity" EXACT [EC:2.1.1.82] synonym: "7-OMT activity" RELATED [EC:2.1.1.82] synonym: "flavonol 7-methyltransferase activity" RELATED [EC:2.1.1.82] synonym: "flavonol 7-O-methyltransferase activity" RELATED [EC:2.1.1.82] synonym: "S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity" EXACT [EC:2.1.1.82] synonym: "S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity" EXACT [EC:2.1.1.82] xref: EC:2.1.1.82 xref: GO:0030757 xref: MetaCyc:2.1.1.82-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004554 name: 3,7-dimethylquercitin 4'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3',4',5-trihydroxy-3,7-dimethoxyflavone = S-adenosyl-L-homocysteine + 3',5-dihydroxy-3,4',7-trimethoxy-flavone." [EC:2.1.1.83] synonym: "3,7-dimethylquercetin 4'-O-methyltransferase activity" EXACT [EC:2.1.1.83] synonym: "4'-OMT activity" RELATED [EC:2.1.1.83] synonym: "flavonol 4'-methyltransferase activity" RELATED [EC:2.1.1.83] synonym: "flavonol 4'-O-methyltransferase activity" RELATED [EC:2.1.1.83] synonym: "S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.83] synonym: "S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity" EXACT [EC:2.1.1.83] xref: EC:2.1.1.83 xref: GO:0030758 xref: MetaCyc:2.1.1.83-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004555 name: methylquercetagetin 6-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3',4',5,6-tetrahydroxy-3,7-dimethoxy-flavone = S-adenosyl-L-homocysteine + 3',4',5-trihydroxy-3,6,7-trimethoxyflavone." [EC:2.1.1.84] synonym: "6-OMT" RELATED [EC:2.1.1.84] synonym: "flavonol 6-methyltransferase activity" EXACT [EC:2.1.1.84] synonym: "flavonol 6-O-methyltransferase activity" RELATED [EC:2.1.1.84] synonym: "S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase activity" EXACT [EC:2.1.1.84] xref: EC:2.1.1.84 xref: GO:0030759 xref: MetaCyc:2.1.1.84-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004556 name: pyridine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + pyridine = S-adenosyl-L-homocysteine + N-methylpyridinium." [EC:2.1.1.87] synonym: "pyridine methyltransferase activity" EXACT [EC:2.1.1.87] synonym: "S-adenosyl-L-methionine:pyridine N-methyltransferase activity" EXACT [EC:2.1.1.87] xref: EC:2.1.1.87 xref: GO:0030760 xref: MetaCyc:PYRIDINE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004557 name: 8-hydroxyquercitin 8-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3,3',4',5,7,8-hexahydroxyflavone = S-adenosyl-L-homocysteine + 3,3',4',5,7-pentahydroxy-8-methoxy-flavone." [EC:2.1.1.88] synonym: "8-hydroxyquercetin 8-O-methyltransferase activity" EXACT [EC:2.1.1.88] synonym: "flavonol 8-methyltransferase activity" EXACT [EC:2.1.1.88] synonym: "flavonol 8-O-methyltransferase activity" RELATED [EC:2.1.1.88] synonym: "S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase activity" EXACT [EC:2.1.1.88] xref: EC:2.1.1.88 xref: GO:0030761 xref: MetaCyc:2.1.1.88-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004558 name: tetrahydrocolumbamine 2-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 5,8,13,13a-tetrahydrocolumbamine = S-adenosyl-L-homocysteine + tetrahydropalmatine." [EC:2.1.1.89] synonym: "S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase activity" EXACT [EC:2.1.1.89] synonym: "tetrahydrocolumbamine methyltransferase activity" EXACT [EC:2.1.1.89] xref: EC:2.1.1.89 xref: GO:0030762 xref: MetaCyc:2.1.1.89-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004559 name: isobutyraldoxime O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 2-methylpropanal oxime = S-adenosyl-L-homocysteine + 2-methylpropanal O-methyloxime." [EC:2.1.1.91] synonym: "aldoxime methyltransferase activity" EXACT [EC:2.1.1.91] synonym: "aldoxime O-methyltransferase activity" EXACT [EC:2.1.1.91] synonym: "S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase activity" EXACT [EC:2.1.1.91] synonym: "S-adenosylmethionine:aldoxime O-methyltransferase activity" EXACT [EC:2.1.1.91] xref: EC:2.1.1.91 xref: GO:0030763 xref: MetaCyc:ISOBUTYRALDOXIME-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004560 name: xanthotoxol O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + O-methylxanthotoxol." [EC:2.1.1.93] synonym: "S-adenosyl-L-methionine:xanthotoxol O-methyltransferase activity" EXACT [EC:2.1.1.93] synonym: "xanthotoxol methyltransferase activity" EXACT [EC:2.1.1.93] xref: EC:2.1.1.93 xref: GO:0030765 xref: MetaCyc:XANTHOTOXOL-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004561 name: 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline." [EC:2.1.1.94] synonym: "11-demethyl-17-deacetylvindoline 11-methyltransferase activity" EXACT [EC:2.1.1.94] synonym: "S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase activity" EXACT [EC:2.1.1.94] synonym: "S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase activity" EXACT [EC:2.1.1.94] synonym: "tabersonine 16-O-methyltransferase activity" EXACT [EC:2.1.1.94] xref: EC:2.1.1.94 xref: GO:0030766 xref: MetaCyc:2.1.1.94-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004562 name: 3-hydroxyanthranilate 4-C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate." [EC:2.1.1.97] synonym: "3-hydroxyanthranilate 4-methyltransferase activity" EXACT [EC:2.1.1.97] synonym: "S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase activity" EXACT [EC:2.1.1.97] xref: EC:2.1.1.97 xref: GO:0030767 xref: MetaCyc:2.1.1.97-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004563 name: 16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxy-tabersonine = S-adenosyl-L-homocysteine + deacetoxyvindoline." [EC:2.1.1.99] synonym: "16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase activity" EXACT [EC:2.1.1.99] synonym: "3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity" EXACT [EC:2.1.1.99] synonym: "NMT activity" EXACT [EC:2.1.1.99] synonym: "S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity" EXACT [EC:2.1.1.99] synonym: "S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity" EXACT [EC:2.1.1.99] xref: EC:2.1.1.99 xref: GO:0030768 xref: MetaCyc:2.1.1.99-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004564 name: macrocin O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + macrocin = S-adenosyl-L-homocysteine + tylosin." [EC:2.1.1.101] subset: gosubset_prok synonym: "macrocin methyltransferase activity" EXACT [EC:2.1.1.101] synonym: "S-adenosyl-L-methionine-macrocin O-methyltransferase activity" EXACT [EC:2.1.1.101] synonym: "S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase activity" EXACT [EC:2.1.1.101] xref: EC:2.1.1.101 xref: GO:0030769 xref: MetaCyc:MACROCIN-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004565 name: demethylmacrocin O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + demethylmacrocin = S-adenosyl-L-homocysteine + macrocin." [EC:2.1.1.102] synonym: "demethylmacrocin methyltransferase activity" EXACT [EC:2.1.1.102] synonym: "S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase activity" EXACT [EC:2.1.1.102] xref: EC:2.1.1.102 xref: GO:0030770 xref: MetaCyc:DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004566 name: N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + N-benzoyl-4-hydroxyanthranilate = S-adenosyl-L-homocysteine + N-benzoyl-4-methoxyanthranilate." [EC:2.1.1.105] synonym: "benzoyl-CoA:anthranilate N-benzoyltransferase" BROAD [EC:2.1.1.105] synonym: "N-benzoyl-4-hydroxyanthranilate 4-methyltransferase activity" EXACT [EC:2.1.1.105] synonym: "S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase activity" EXACT [EC:2.1.1.105] xref: EC:2.1.1.105 xref: GO:0030771 xref: MetaCyc:2.1.1.105-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004567 name: tryptophan 2-C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan." [EC:2.1.1.106] synonym: "S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase activity" EXACT [EC:2.1.1.106] synonym: "S-adenosylmethionine:tryptophan 2-methyltransferase activity" EXACT [EC:2.1.1.106] synonym: "tryptophan 2-methyltransferase activity" EXACT [EC:2.1.1.106] xref: EC:2.1.1.106 xref: GO:0030772 xref: MetaCyc:TRYPTOPHAN-2-C-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004568 name: 6-hydroxymellein O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 6-hydroxymellein = S-adenosyl-L-homocysteine + 6-methoxymellein." [EC:2.1.1.108] synonym: "6-hydroxymellein methyltransferase activity" EXACT [EC:2.1.1.108] synonym: "S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase activity" EXACT [EC:2.1.1.108] xref: EC:2.1.1.108 xref: GO:0030773 xref: MetaCyc:6-HYDROXYMELLEIN-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004569 name: anthranilate N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = S-adenosyl-L-homocysteine + N-methylanthranilate." [EC:2.1.1.111] synonym: "anthranilic acid N-methyltransferase activity" EXACT [EC:2.1.1.111] synonym: "S-adenosyl-L-methionine:anthranilate N-methyltransferase activity" EXACT [EC:2.1.1.111] xref: EC:2.1.1.111 xref: GO:0030774 xref: MetaCyc:ANTHRANILATE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004570 name: glucuronoxylan 4-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate." [EC:2.1.1.112] synonym: "S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase activity" EXACT [EC:2.1.1.112] xref: EC:2.1.1.112 xref: GO:0030775 xref: MetaCyc:GLUCURONOXYLAN-4-O-METHYLTRANSFERASE-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004573 name: columbamine O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + palmatine." [EC:2.1.1.118] synonym: "S-adenosyl-L-methionine:columbamine O-methyltransferase activity" EXACT [EC:2.1.1.118] xref: EC:2.1.1.118 xref: GO:0030778 xref: MetaCyc:2.1.1.118-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004574 name: 10-hydroxydihydrosanguinarine 10-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine." [EC:2.1.1.119] synonym: "S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase activity" EXACT [EC:2.1.1.119] xref: EC:2.1.1.119 xref: GO:0030779 xref: MetaCyc:2.1.1.119-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004575 name: 12-hydroxydihydrochelirubine 12-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-homocysteine + dihydromacarpine." [EC:2.1.1.120] synonym: "S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase activity" EXACT [EC:2.1.1.120] xref: EC:2.1.1.120 xref: GO:0030780 xref: MetaCyc:2.1.1.120-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004576 name: 6-O-methylnorlaudanosoline 5'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline." [EC:2.1.1.121] synonym: "S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity" EXACT [EC:2.1.1.121] xref: EC:2.1.1.121 xref: GO:0030781 xref: MetaCyc:2.1.1.121-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004579 name: 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline." [EC:2.1.1.116] synonym: "S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity" EXACT [EC:2.1.1.116] xref: EC:2.1.1.116 xref: GO:0030784 xref: MetaCyc:2.1.1.116-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004582 name: inositol 4-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + myo-inositol = S-adenosyl-L-homocysteine + 4-methyl-myo-inositol." [EC:2.1.1.129] synonym: "myo-inositol 4-O-methyltransferase activity" EXACT [EC:2.1.1.129] synonym: "myo-inositol 6-O-methyltransferase activity" RELATED [EC:2.1.1.129] synonym: "S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase activity" EXACT [EC:2.1.1.129] synonym: "S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase activity" EXACT [EC:2.1.1.129] xref: EC:2.1.1.129 xref: GO:0030787 xref: MetaCyc:2.1.1.129-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004583 name: precorrin-2 C20-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + precorrin-3A." [EC:2.1.1.130] subset: gosubset_prok synonym: "S-adenosyl-L-methionine--precorrin-2 methyltransferase activity" EXACT [EC:2.1.1.130] synonym: "S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase activity" EXACT [EC:2.1.1.130] xref: EC:2.1.1.130 xref: GO:0030788 xref: MetaCyc:2.1.1.130-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004584 name: precorrin-3B C17-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4." [EC:2.1.1.131] subset: gosubset_prok synonym: "CobJ" RELATED [EC:2.1.1.131] synonym: "precorrin-3 methylase activity" EXACT [EC:2.1.1.131] synonym: "precorrin-3 methyltransferase activity" EXACT [EC:2.1.1.131] synonym: "S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase activity" EXACT [EC:2.1.1.131] xref: EC:2.1.1.131 xref: GO:0030789 xref: MetaCyc:2.1.1.131-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004585 name: chlorophenol O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole." [EC:2.1.1.136] synonym: "halogenated phenol O-methyltransferase activity" BROAD [EC:2.1.1.136] synonym: "S-adenosyl-L-methionine:trichlorophenol O-methyltransferase activity" EXACT [EC:2.1.1.136] synonym: "trichlorophenol O-methyltransferase activity" EXACT [EC:2.1.1.136] xref: EC:2.1.1.136 xref: GO:0030790 xref: MetaCyc:2.1.1.136-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004586 name: arsenite methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate." [EC:2.1.1.137] comment: Note that the enzyme arsenite methyltransferase also has methylarsonite methyltransferase activity (GO:0030792). synonym: "S-adenosyl-L-methionine:arsenic(III) methyltransferase activity" EXACT [EC:2.1.1.137] synonym: "S-adenosyl-L-methionine:arsenite As-methyltransferase activity" EXACT [EC:2.1.1.137] synonym: "S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity" EXACT [EC:2.1.1.137] xref: EC:2.1.1.137 xref: GO:0030791 xref: MetaCyc:2.1.1.137-RXN xref: UM-BBD_enzymeID:e0515 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004587 name: methylarsonite methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate." [EC:2.1.1.138] comment: Note that EC:2.1.1.138 was deleted from EC as the reaction is performed by arsenite methyltransferase (EC:2.1.1.137). xref: EC:2.1.1.- xref: GO:0030792 xref: MetaCyc:2.1.1.138-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004588 name: 3'-demethylstaurosporine O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3'-demethylstaurosporine = S-adenosyl-L-homocysteine + staurosporine." [EC:2.1.1.139] synonym: "3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase activity" EXACT [EC:2.1.1.139] synonym: "S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase activity" EXACT [EC:2.1.1.139] synonym: "staurosporine synthase activity" EXACT [EC:2.1.1.139] xref: EC:2.1.1.139 xref: GO:0030793 xref: MetaCyc:2.1.1.139-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004590 name: jasmonate O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + jasmonate = S-adenosyl-L-homocysteine + methyljasmonate." [EC:2.1.1.141] synonym: "jasmonic acid carboxyl methyltransferase activity" EXACT [EC:2.1.1.141] synonym: "S-adenosyl-L-methionine:jasmonate O-methyltransferase activity" EXACT [EC:2.1.1.141] synonym: "S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity" EXACT [] xref: EC:2.1.1.141 xref: GO:0030795 xref: GO:0045546 xref: MetaCyc:RXN1F-28 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004591 name: cycloartenol 24-C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = S-adenosyl-L-homocysteine + (24R)-24-methylcycloarta-8,25-dien-3N2-ol." [EC:2.1.1.142] synonym: "S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase activity" EXACT [EC:2.1.1.142] synonym: "sterol C-methyltransferase activity" BROAD [EC:2.1.1.142] xref: EC:2.1.1.142 xref: GO:0030796 xref: MetaCyc:2.1.1.142-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004592 name: 24-methylenesterol C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 24-methylenelophenol = S-adenosyl-L-homocysteine + (Z)-24-ethylidenelophenol." [EC:2.1.1.143] synonym: "24-methylenelophenol C-24(1)-methyltransferase activity" EXACT [EC:2.1.1.143] synonym: "24-methylenelophenol C-241-methyltransferase activity" EXACT [EC:2.1.1.143] synonym: "S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase activity" EXACT [EC:2.1.1.143] synonym: "SMT(2) activity" NARROW [EC:2.1.1.143] synonym: "SMT2" RELATED [EC:2.1.1.143] xref: EC:2.1.1.143 xref: GO:0030797 xref: MetaCyc:2.1.1.143-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004593 name: trans-aconitate 2-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate." [EC:2.1.1.144] subset: gosubset_prok synonym: "S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase activity" EXACT [EC:2.1.1.144] xref: EC:2.1.1.144 xref: GO:0030798 xref: MetaCyc:RXN0-2441 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0004594 name: threo-3-hydroxyaspartate ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: threo-3-hydroxy-L-aspartate = oxaloacetate + NH3." [EC:4.3.1.16, PMID:10481099] synonym: "3-hydroxyaspartate dehydratase activity" BROAD [GOC:mcc, PMID:10481099] synonym: "L-threo-3-hydroxyaspartate dehydratase activity" EXACT [EC:4.3.1.16] synonym: "threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)" EXACT [EC:4.3.1.16] synonym: "threo-3-hydroxy-L-aspartate ammonia-lyase activity" EXACT [EC:4.3.1.16] synonym: "threo-3-hydroxyaspartate dehydratase activity" EXACT [EC:4.3.1.16] xref: EC:4.3.1.16 xref: GO:0030848 xref: MetaCyc:4.3.1.16-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0004595 name: beta-2-microglobulin binding namespace: molecular_function def: "Interacting selectively with beta-2-microglobulin." [GOC:mah] xref: GO:0030881 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004596 name: lipid antigen binding namespace: molecular_function def: "Interacting selectively with a lipid antigen." [PMID:14500461] xref: GO:0030882 is_a: CCO:F0000342 ! antigen binding is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0004597 name: endogenous lipid antigen binding namespace: molecular_function def: "Interacting selectively with an endogenous cellular lipid antigen." [PMID:14500461] xref: GO:0030883 is_a: CCO:F0004596 ! lipid antigen binding [Term] id: CCO:F0004598 name: exogenous lipid antigen binding namespace: molecular_function def: "Interacting selectively with an exogenous lipid antigen (examples include microbial lipids and glycolipids)." [PMID:14500461] xref: GO:0030884 is_a: CCO:F0004596 ! lipid antigen binding [Term] id: CCO:F0004599 name: actin-dependent ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, requiring the presence of an actin filament to accelerate release of ADP and phosphate." [GOC:mah] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "actin-activated ATPase activity" EXACT [] xref: GO:0030898 is_a: CCO:F0005696 ! ATPase activity, coupled [Term] id: CCO:F0004600 name: calcium-dependent ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, requiring the presence of calcium ion (Ca2+)." [GOC:mah] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. xref: GO:0030899 is_a: CCO:F0005696 ! ATPase activity, coupled [Term] id: CCO:F0004601 name: TPR domain binding namespace: molecular_function def: "Interacting selectively with a tetratricopeptide repeat (TPR) domain of a protein, the consensu thes sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices." [GOC:mah] xref: GO:0030911 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004602 name: dopachrome decarboxylase activity namespace: molecular_function def: "Catalysis of the decarboxylation of L-dopachrome to form 5,6-dihydroxyindole." [PMID:12164780] synonym: "dopachrome conversion activity" BROAD [] xref: GO:0030928 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0004603 name: chloroplast targeting sequence binding namespace: molecular_function def: "Interacting selectively with a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast." [GOC:mah] xref: GO:0030941 is_a: CCO:F0001368 ! signal sequence binding [Term] id: CCO:F0004604 name: endoplasmic reticulum signal peptide binding namespace: molecular_function def: "Interacting selectively with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum." [GOC:mah] synonym: "ER signal peptide binding" EXACT [] xref: GO:0030942 is_a: CCO:F0001368 ! signal sequence binding [Term] id: CCO:F0004605 name: mitochondrion targeting sequence binding namespace: molecular_function def: "Interacting selectively with a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion." [GOC:mah] synonym: "mitochondrial targeting sequence binding" EXACT [] xref: GO:0030943 is_a: CCO:F0001368 ! signal sequence binding [Term] id: CCO:F0004606 name: DDEL sequence binding namespace: molecular_function def: "Interacting selectively with a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum." [GOC:mah] xref: GO:0030944 is_a: CCO:F0006275 ! ER retention sequence binding [Term] id: CCO:F0004607 name: protein tyrosine phosphatase activity, via thiol-phosphate intermediate namespace: molecular_function def: "The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate." [GOC:hjd] xref: GO:0030945 is_a: CCO:F0001090 ! protein tyrosine phosphatase activity [Term] id: CCO:F0004608 name: protein tyrosine phosphatase activity, metal-dependent namespace: molecular_function def: "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate, by a mechanism that requires metal ions." [GOC:mah] xref: GO:0030946 is_a: CCO:F0001090 ! protein tyrosine phosphatase activity [Term] id: CCO:F0004609 name: potassium ion binding namespace: molecular_function def: "Interacting selectively with potassium (K+) ions." [GOC:mah] subset: gosubset_prok xref: GO:0030955 is_a: CCO:F0004664 ! alkali metal ion binding [Term] id: CCO:F0004610 name: Tat protein binding namespace: molecular_function def: "Interacting selectively with Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus." [GOC:mah, PMID:9094689] xref: GO:0030957 is_a: CCO:F0001738 ! transcription factor binding [Term] id: CCO:F0004611 name: receptor tyrosine kinase binding namespace: molecular_function def: "Interacting selectively with a receptor that possesses protein tyrosine kinase activity." [GOC:mah] synonym: "transmembrane receptor protein tyrosine kinase ligand binding" RELATED [] xref: GO:0030971 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0004612 name: molybdate ion binding namespace: molecular_function def: "Interacting selectively with molybdate (MoO4 2-) ions." [GOC:mlg] subset: gosubset_prok xref: GO:0030973 is_a: CCO:F0005807 ! anion binding [Term] id: CCO:F0004613 name: thiamin binding namespace: molecular_function def: "Interacting selectively with thiamin (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver." [GOC:mlg] synonym: "thiamine binding" EXACT [] synonym: "vitamin B1 binding" EXACT [] xref: GO:0030975 is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0004614 name: thiamin pyrophosphate binding namespace: molecular_function def: "Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases." [GOC:mlg, http://cancerweb.ncl.ac.uk/] synonym: "aneurine pyrophosphate binding" EXACT [] synonym: "cocarboxylase binding" EXACT [] synonym: "diphosphothiamin binding" EXACT [] synonym: "thiamine pyrophosphate binding" EXACT [] synonym: "TPP binding" EXACT [] xref: GO:0030976 is_a: CCO:F0004191 ! vitamin binding is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0004615 name: taurine binding namespace: molecular_function def: "Interacting selectively with taurine." [GOC:mlg] xref: GO:0030977 is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0004616 name: mismatched DNA binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing one or more mismatches." [GOC:mah] xref: GO:0030983 is_a: CCO:F0000282 ! double-stranded DNA binding [Term] id: CCO:F0004617 name: kininogen binding namespace: molecular_function def: "Interacting selectively with a kininogen, any of a group of plasma proteins that are kinin precursors." [GOC:mah, PMID:9520414] xref: GO:0030984 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004618 name: high molecular weight kininogen binding namespace: molecular_function def: "Interacting selectively with a kininogen of high molecular mass." [GOC:mah, PMID:9520414] synonym: "HK binding" EXACT [] synonym: "HMW kininogen binding" EXACT [] xref: GO:0030985 is_a: CCO:F0004617 ! kininogen binding [Term] id: CCO:F0004619 name: low molecular weight kininogen binding namespace: molecular_function def: "Interacting selectively with a kininogen of low molecular mass." [GOC:mah, PMID:9520414] synonym: "LK binding" EXACT [] synonym: "LMW kininogen binding" EXACT [] xref: GO:0030986 is_a: CCO:F0004617 ! kininogen binding [Term] id: CCO:F0004620 name: high molecular weight kininogen receptor binding namespace: molecular_function def: "Interacting selectively with a high molecular weight kininogen receptor." [GOC:mah] xref: GO:0030987 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0004621 name: filamin binding namespace: molecular_function def: "Interacting selectively with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain." [GOC:mah, PMID:11336782] xref: GO:0031005 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004622 name: filamin-A binding namespace: molecular_function def: "Interacting selectively with filamin-A." [GOC:mah, PMID:11336782] synonym: "ABP-280 binding" NARROW [] synonym: "alpha-filamin binding" NARROW [] synonym: "filamin A binding" EXACT [] synonym: "filamin-1 binding" NARROW [] xref: GO:0031006 is_a: CCO:F0004621 ! filamin binding [Term] id: CCO:F0004623 name: filamin-B binding namespace: molecular_function def: "Interacting selectively with filamin-B." [GOC:mah, PMID:11336782] synonym: "ABP-278/276 binding" NARROW [] synonym: "beta-filamin binding" NARROW [] synonym: "filamin B binding" EXACT [] synonym: "filamin-3 binding" NARROW [] xref: GO:0031007 is_a: CCO:F0004621 ! filamin binding [Term] id: CCO:F0004624 name: filamin-C binding namespace: molecular_function def: "Interacting selectively with filamin-C, a filamin isoform that contains an 81 amino acid insertion in repeat 20, not present in filamin-A or -B." [GOC:mah, PMID:11336782] synonym: "ABPL binding" NARROW [] synonym: "filamin C binding" EXACT [] synonym: "filamin-2 binding" NARROW [] synonym: "gamma-filamin binding" NARROW [] xref: GO:0031008 is_a: CCO:F0004621 ! filamin binding [Term] id: CCO:F0004625 name: troponin I binding namespace: molecular_function def: "Interacting selectively with troponin I, the inhibitory subunit of the troponin complex." [GOC:mah, ISBN:0815316194] xref: GO:0031013 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004626 name: troponin T binding namespace: molecular_function def: "Interacting selectively with troponin T, the tropomyosin-binding subunit of the troponin complex." [GOC:mah, ISBN:0815316194] xref: GO:0031014 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004627 name: cysteine desulfurase activity namespace: molecular_function def: "Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine." [EC:2.8.1.7] subset: gosubset_prok synonym: "cysteine desulfurylase activity" EXACT [EC:2.8.1.7] synonym: "IscS" RELATED [EC:2.8.1.7] synonym: "L-cysteine:enzyme cysteine sulfurtransferase activity" EXACT [EC:2.8.1.7] synonym: "NIFS" RELATED [EC:2.8.1.7] synonym: "NifS" RELATED [EC:2.8.1.7] synonym: "SufS" RELATED [EC:2.8.1.7] xref: EC:2.8.1.7 xref: GO:0031071 is_a: CCO:F0003355 ! sulfurtransferase activity [Term] id: CCO:F0004628 name: heat shock protein binding namespace: molecular_function def: "Interacting selectvely with a heat shock protein, any protein synthesized or activated in response to heat shock." [GOC:mah] xref: GO:0031072 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004629 name: cholesterol 26-hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol." [GOC:mah, PMID:950499] xref: GO:0031073 is_a: CCO:F0001866 ! steroid hydroxylase activity [Term] id: CCO:F0004630 name: histone deacetylase activity (H3-K14 specific) namespace: molecular_function def: "Catalysis of the removal of an acetyl group from lysine at position 14 of the histone H3 protein." [GOC:mah, PMID:11884604] xref: GO:0031078 is_a: CCO:F0000816 ! histone deacetylase activity [Term] id: CCO:F0004631 name: picornain 3C activity namespace: molecular_function def: "Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly." [EC:3.4.22.28] synonym: "3C protease activity" EXACT [EC:3.4.22.28] synonym: "3C proteinase activity" EXACT [EC:3.4.22.28] synonym: "coxsackievirus 3C proteinase activity" EXACT [EC:3.4.22.28] synonym: "cysteine proteinase 3C" RELATED [EC:3.4.22.28] synonym: "foot-and-mouth protease 3C activity" NARROW [EC:3.4.22.28] synonym: "foot-and-mouth-disease virus proteinase 3C" RELATED [EC:3.4.22.28] synonym: "hepatitis A virus 3C proteinase activity" EXACT [EC:3.4.22.28] synonym: "picornavirus endopeptidase 3C activity" NARROW [EC:3.4.22.28] synonym: "poliovirus protease 3C activity" NARROW [EC:3.4.22.28] synonym: "poliovirus proteinase 3C" RELATED [EC:3.4.22.28] synonym: "protease 3C" RELATED [EC:3.4.22.28] synonym: "rhinovirus protease 3C activity" NARROW [EC:3.4.22.28] synonym: "rhinovirus proteinase 3C" RELATED [EC:3.4.22.28] synonym: "tomato ringspot nepovirus 3C-related protease" RELATED [EC:3.4.22.28] xref: EC:3.4.22.28 xref: GO:0031079 is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0004632 name: alpha(1,2)-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,2)-linkage." [GOC:mah] subset: gosubset_prok xref: GO:0031127 is_a: CCO:F0001884 ! fucosyltransferase activity [Term] id: CCO:F0004633 name: serine 3-dehydrogenase namespace: molecular_function def: "L-serine + NADP+ = 2-ammoniomalonate semialdehyde + NADPH + H+." [EC:1.1.1.276] synonym: "L-serine:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.276] xref: EC:1.1.1.276 xref: GO:0031132 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004634 name: histone lysine N-methyltransferase activity (H3-K79 specific) namespace: molecular_function def: "Catalysis of the addition of a methyl group onto lysine at position 79 of the histone H3 protein." [GOC:mah, PMID:15371351] xref: GO:0031151 is_a: CCO:F0003617 ! histone-lysine N-methyltransferase activity [Term] id: CCO:F0004635 name: ornithine N5-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-ornithine + O2 + donor-H2 = N5-hydroxy-L-ornithine + acceptor + H2O." [GOC:mah, PMID:12828635] xref: GO:0031172 is_a: CCO:F0000894 ! monooxygenase activity [Term] id: CCO:F0004636 name: endo-1,4-beta-xylanase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans." [EC:3.2.1.8] synonym: "1,4-beta-D-xylan xylanohydrolase activity" EXACT [EC:3.2.1.8] synonym: "1,4-beta-xylan xylanohydrolase activity" EXACT [EC:3.2.1.8] synonym: "beta-1,4-xylan xylanohydrolase activity" EXACT [EC:3.2.1.8] synonym: "beta-1,4-xylanase activity" EXACT [EC:3.2.1.8] synonym: "beta-D-xylanase activity" EXACT [EC:3.2.1.8] synonym: "beta-xylanase activity" EXACT [EC:3.2.1.8] synonym: "endo-(1->4)-beta-xylanase(1->4)-beta-xylan 4-xylanohydrolase activity" EXACT [EC:3.2.1.8] synonym: "endo-1,4-b-xylanase activity" EXACT [] synonym: "endo-1,4-beta-D-xylanase activity" EXACT [EC:3.2.1.8] synonym: "endo-1,4-xylanase activity" EXACT [EC:3.2.1.8] synonym: "endo-beta-1,4-xylanase activity" EXACT [EC:3.2.1.8] synonym: "xylanase" BROAD [EC:3.2.1.8] xref: EC:3.2.1.8 xref: GO:0031176 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0004637 name: phosphopantetheine binding namespace: molecular_function def: "Interacting selectizely with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate)." [ChEBI:16858, GOC:mah] xref: GO:0031177 is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0004638 name: RNA splicing factor activity, transesterification mechanism namespace: molecular_function def: "An activity which assists splicing of substrate RNA(s) by facilitating the formation and stabilization of a series of catalytic conformations in which key RNA sequences are positioned for a series of two transesterification reactions which result in removal of the intron sequence and joining of two exons." [GOC:krc] comment: Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism. synonym: "pre-mRNA splicing factor activity" RELATED [] synonym: "spliceosomal catalysis" EXACT [] xref: GO:0000385 xref: GO:0031202 xref: Reactome:160901 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0004639 name: POZ domain binding namespace: molecular_function def: "Interacting selectively with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors." [PMID:7958847] xref: GO:0031208 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004640 name: phosphatidylcholine binding namespace: molecular_function def: "Interacting selectively with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0031210 is_a: CCO:F0001666 ! phospholipid binding [Term] id: CCO:F0004641 name: neopullulanase activity namespace: molecular_function def: "Catalysis of the hydrolysis of pullulan to panose (6-a-D-glucosylmaltose)." [EC:3.2.1.135, GOC:mlg] synonym: "pullulan 4-D-glucanohydrolase (panose-forming)" EXACT [EC:3.2.1.135] synonym: "pullulanase II activity" EXACT [] xref: EC:3.2.1.135 xref: GO:0031216 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0004642 name: glucan 1,4-beta-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of 1,4-linkages in 1,4-beta-D-glucans, to remove successive glucose units." [EC:3.2.1.74, GOC:mlg] synonym: "1,4-beta-D-glucan glucohydrolase activity" EXACT [EC:3.2.1.74] synonym: "beta-1,4-beta-glucanase activity" EXACT [EC:3.2.1.74] synonym: "beta-1,4-glucanase activity" EXACT [] synonym: "exo-1,4-beta-D-glucosidase activity" EXACT [EC:3.2.1.74] synonym: "exo-1,4-beta-glucanase activity" EXACT [] synonym: "exo-1,4-beta-glucosidase activity" EXACT [] synonym: "exo-beta-1,4-glucanase activity" EXACT [] synonym: "exo-beta-1,4-glucosidase activity" EXACT [] synonym: "exocellulase activity" EXACT [] xref: EC:3.2.1.74 xref: GO:0031217 is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0004643 name: arabinogalactan endo-1,4-beta-galactosidase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in arabinogalactans." [EC:3.2.1.89, GOC:mlg] synonym: "arabinogalactan 4-beta-D-galactanohydrolase activity" EXACT [EC:3.2.1.89] synonym: "arabinogalactanase activity" EXACT [] synonym: "endo-1,4-beta-galactanase activity" EXACT [] synonym: "galactanase activity" EXACT [] xref: EC:3.2.1.89 xref: GO:0031218 is_a: CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds [Term] id: CCO:F0004644 name: levanase activity namespace: molecular_function def: "Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units." [EC:3.2.1.65, GOC:mlg] synonym: "2,6-beta-D-fructan fructanohydrolase activity" EXACT [EC:3.2.1.65] synonym: "levan hydrolase activity" EXACT [] xref: EC:3.2.1.65 xref: GO:0031219 is_a: CCO:F0003368 ! hydrolase activity, acting on glycosyl bonds [Term] id: CCO:F0004645 name: maltodextrin phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: maltodextrin = glucose-1-phosphate." [GOC:mlg, PMID:10348846] xref: GO:0031220 is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0004646 name: denatured protein binding namespace: molecular_function def: "Interacting selectively with denatured proteins." [GOC:mlg] comment: Note that this term should not be confused with 'unfolded protein binding ; GO:0051082', which usually refers to proteins that have not yet folded into their active states. Denatured proteins once were in their correct functional conformations, but have become incorrectly folded, and often form aggregates. xref: GO:0031249 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004647 name: amine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in)." [GOC:mlg] subset: gosubset_prok synonym: "amine ABC transporter" NARROW [] xref: GO:0031263 is_a: CCO:F0001529 ! amine transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0004648 name: small GTPase binding namespace: molecular_function def: "Interacting selectively with a small monomeric GTPase." [GOC:mah] xref: GO:0031267 is_a: CCO:F0008038 ! GTPase binding [Term] id: CCO:F0004649 name: alpha-1,2-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage." [PMID:7522655] xref: EC:2.4.1.- xref: GO:0031278 is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0004650 name: taurine-pyruvate aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde." [EC:2.6.1.77] synonym: "taurine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.77] synonym: "Tpa" RELATED [EC:2.6.1.77] xref: EC:2.6.1.77 xref: GO:0031299 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0004651 name: hexitol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor." [GOC:mah] subset: gosubset_prok xref: GO:0031320 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0004652 name: Pro-X metallocarboxypeptidase activity namespace: molecular_function def: "Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid." [EC:3.4.17.16, GOC:mah] synonym: "carboxypeptidase P activity" NARROW [EC:3.4.17.16] synonym: "membrane Pro-X carboxypeptidase activity" NARROW [EC:3.4.17.16] synonym: "membrane Pro-Xaa carboxypeptidase" NARROW [] synonym: "microsomal carboxypeptidase activity" NARROW [EC:3.4.17.16] xref: EC:3.4.17.16 xref: GO:0031368 is_a: CCO:F0000650 ! metallocarboxypeptidase activity is_a: CCO:F0001834 ! Pro-X carboxypeptidase activity [Term] id: CCO:F0004653 name: translation initiation factor binding namespace: molecular_function def: "Interacting selectively with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation." [GOC:mah] xref: GO:0031369 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004654 name: eukaryotic initiation factor 4G binding namespace: molecular_function def: "Interacting selectively with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation." [GOC:mah] synonym: "eIF4G binding" EXACT [] xref: GO:0031370 is_a: CCO:F0004653 ! translation initiation factor binding [Term] id: CCO:F0004655 name: protein tag namespace: molecular_function def: "Acting as an indicator or marker to facilitate recognition by other molecules in the cell. Recognition of the tag, which can be covalently attached to the target molecule, may result in modification, sequestration, transport or degradation of the molecule in question." [GOC:go_curators] subset: goslim_generic subset: goslim_pir synonym: "protein tagging activity" RELATED [] synonym: "ubiquitin" RELATED [] xref: GO:0031386 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0004656 name: sodium ion binding namespace: molecular_function def: "Interacting selectively with sodium ions (Na+)." [GOC:mah] subset: gosubset_prok xref: GO:0031402 is_a: CCO:F0004664 ! alkali metal ion binding [Term] id: CCO:F0004657 name: lithium ion binding namespace: molecular_function def: "Interacting selectively with lithium ions (Li+)." [GOC:mah] subset: gosubset_prok xref: GO:0031403 is_a: CCO:F0004664 ! alkali metal ion binding [Term] id: CCO:F0004658 name: chloride ion binding namespace: molecular_function def: "Interacting selectively with chloride ions (Cl-)." [GOC:mah] subset: gosubset_prok synonym: "chloride binding" EXACT [] xref: GO:0031404 is_a: CCO:F0005807 ! anion binding [Term] id: CCO:F0004659 name: lipoic acid binding namespace: molecular_function def: "Interacting selectively with lipoic acid, 1,2-dithiolane-3-pentanoic acid." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0031405 is_a: CCO:F0004660 ! carboxylic acid binding is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0004660 name: carboxylic acid binding namespace: molecular_function def: "Interacting selectively with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0031406 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0004661 name: pigment binding namespace: molecular_function def: "Interacting selectively with a pigment, any general or particular coloring matter in living organisms, e.g. melanin." [GOC:mah] subset: goslim_pir subset: gosubset_prok xref: GO:0031409 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0004662 name: L-ascorbic acid binding namespace: molecular_function def: "Interacting selectively with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species." [ChEBI:38290, GOC:mah] synonym: "L-ascorbate binding" EXACT [] synonym: "vitamin C binding" EXACT [] xref: GO:0031418 is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0004663 name: cobalamin binding namespace: molecular_function def: "Interacting lelectively with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom." [GOC:mah] synonym: "vitamin B12 binding" EXACT [] xref: GO:0031419 is_a: CCO:F0004191 ! vitamin binding [Term] id: CCO:F0004664 name: alkali metal ion binding namespace: molecular_function def: "Interacting selectively with any alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen." [GOC:mah] subset: gosubset_prok xref: GO:0031420 is_a: CCO:F0005808 ! cation binding is_a: CCO:F0006257 ! metal ion binding [Term] id: CCO:F0004665 name: hexon binding namespace: molecular_function def: "Interacting selectively with a hexon, the major protein component of the icosahedral capsid of an adenovirus." [GOC:mah, PMID:12915569] xref: GO:0031423 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004666 name: titin binding namespace: molecular_function def: "Interacting selectively with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively." [GOC:mah, PMID:10481174] xref: GO:0031432 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004667 name: telethonin binding namespace: molecular_function def: "Interacting selectively with telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase." [GOC:mah, PMID:10481174] xref: GO:0031433 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0004668 name: mitogen-activated protein kinase kinase binding namespace: molecular_function def: "Interacting selectively with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase." [GOC:mah] synonym: "MAPKK binding" EXACT [] xref: GO:0031434 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0004669 name: mitogen-activated protein kinase kinase kinase binding namespace: molecular_function def: "Interacting selectively with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase." [GOC:bf] synonym: "MAPKKK binding" EXACT [] xref: GO:0031435 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0004670 name: betaine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in)." [GOC:mlg] synonym: "betaine ABC transporter" NARROW [] xref: GO:0031458 is_a: CCO:F0004647 ! amine-transporting ATPase activity [Term] id: CCO:F0004671 name: glycine betaine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in)." [GOC:mlg] synonym: "glycine betaine ABC transporter" NARROW [] synonym: "N-trimethylglycine-transporting ATPase activity" EXACT [] xref: GO:0031459 is_a: CCO:F0004670 ! betaine-transporting ATPase activity [Term] id: CCO:F0004672 name: myosin III binding namespace: molecular_function def: "Interacting selectively with a class III myosin; myosin III is monomeric and has an N terminal kinase domain." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031473 is_a: CCO:F0003516 ! myosin binding [Term] id: CCO:F0004673 name: myosin V binding namespace: molecular_function def: "Interacting selectively with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0031489 is_a: CCO:F0003516 ! myosin binding [Term] id: CCO:F0004674 name: chromatin DNA binding namespace: molecular_function def: "Interacting selectively with DNA that is assembled into chromatin." [GOC:mah] xref: GO:0031490 is_a: CCO:F0000278 ! chromatin binding is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0004675 name: nucleosome binding namespace: molecular_function def: "Interacting selectively with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures." [GOC:mah] xref: GO:0031491 is_a: CCO:F0000278 ! chromatin binding [Term] id: CCO:F0004676 name: nucleosomal DNA binding namespace: molecular_function def: "Interacting selectively with the DNA portion of a nucleosome." [GOC:mah] xref: GO:0031492 is_a: CCO:F0004674 ! chromatin DNA binding is_a: CCO:F0004675 ! nucleosome binding [Term] id: CCO:F0004677 name: nucleosomal histone binding namespace: molecular_function def: "Interacting selectively with a histone that is assembled into a nucleosome." [GOC:mah] xref: GO:0031493 is_a: CCO:F0004675 ! nucleosome binding is_a: CCO:F0005669 ! histone binding [Term] id: CCO:F0004678 name: far-red light photoreceptor activity namespace: molecular_function def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation." [GOC:nln] xref: GO:0031516 is_a: CCO:F0002412 ! red or far-red light photoreceptor activity [Term] id: CCO:F0004679 name: red light photoreceptor activity namespace: molecular_function def: "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation." [GOC:nln] xref: GO:0031517 is_a: CCO:F0002412 ! red or far-red light photoreceptor activity [Term] id: CCO:F0004680 name: gonadotropin-releasing hormone receptor binding namespace: molecular_function def: "Interacting selectively with a receptor for gonadotropin-releasing hormone, a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary." [PMID:15196882] xref: GO:0031530 is_a: CCO:F0008110 ! peptide hormone receptor binding [Term] id: CCO:F0004681 name: thyrotropin-releasing hormone receptor binding namespace: molecular_function def: "Interacting selectively with a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary." [PMID:8592728] synonym: "thyrotropin-releasing hormone receptor ligand" NARROW [] xref: GO:0031531 xref: GO:0031888 is_a: CCO:F0000196 ! G-protein-coupled receptor binding is_a: CCO:F0008110 ! peptide hormone receptor binding [Term] id: CCO:F0004682 name: peptidyl-proline dioxygenase activity namespace: molecular_function def: "Catalysis of the transfer of a hydroxyl group from 2-oxoglutarate to a prolyl residue in a protein." [GOC:mah] xref: GO:0031543 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0004683 name: peptidyl-proline 3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2." [GOC:mah] xref: GO:0031544 is_a: CCO:F0004682 ! peptidyl-proline dioxygenase activity [Term] id: CCO:F0004684 name: peptidyl-proline 4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2." [GOC:mah] synonym: "HIF-type prolyl 4-hydroxylase" NARROW [] synonym: "prolyl 4-hydroxylase" BROAD [] xref: GO:0031545 is_a: CCO:F0004682 ! peptidyl-proline dioxygenase activity [Term] id: CCO:F0004685 name: brain-derived neurotrophic factor receptor binding namespace: molecular_function def: "Interacting selectively with the brain-derived neurotrophic factor receptor." [GOC:mah] synonym: "BDNF receptor binding" EXACT [] synonym: "brain-derived neurotrophic factor ligand" NARROW [] xref: GO:0031546 is_a: CCO:F0001466 ! neurotrophin receptor binding [Term] id: CCO:F0004686 name: oxidosqualene cyclase activity namespace: molecular_function def: "Catalysis of the cyclization of (S)-2,3-epoxysqualene to triterpene." [GOC:ct] subset: gosubset_prok xref: GO:0031559 is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0004687 name: polyubiquitin binding namespace: molecular_function def: "Interacting selectively and non-covalently with a polymer of ubiqutin." [GOC:mah] synonym: "multiubiquitin binding" RELATED [] xref: GO:0031593 is_a: CCO:F0005797 ! ubiquitin binding [Term] id: CCO:F0004688 name: ubiquitin conjugating enzyme binding namespace: molecular_function def: "Interacting selectively with a ubiquitin conjugating enzyme, any of the E2 proteins." [GOC:vp] xref: GO:0031624 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0004689 name: ubiquitin protein ligase binding namespace: molecular_function def: "Interacting selectively with a ubiquitin protein ligase enzyme, any of the E3 proteins." [GOC:vp] synonym: "ubiquitin ligase binding" EXACT [] xref: GO:0031625 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0004690 name: beta-endorphin binding namespace: molecular_function def: "Interacting selectively with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin." [GOC:nln, PMID:6267560] xref: GO:0031626 is_a: CCO:F0005633 ! neurotransmitter binding [Term] id: CCO:F0004691 name: opioid receptor binding namespace: molecular_function def: "Interacting selectively with an opioid receptor." [GOC:nln] xref: GO:0031628 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004692 name: replication fork barrier binding namespace: molecular_function def: "Interacting selectively with replication fork barriers, sites that inhibit the progress of replication forks." [GOC:mah] xref: GO:0031634 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0004693 name: adrenocorticotropin-releasing hormone receptor activity namespace: molecular_function def: "Combining with adrenocorticotropin-releasing hormone to initiate a change in cell activity." [GOC:mah] xref: GO:0031636 is_a: CCO:F0003530 ! adrenocorticotropin-releasing hormone binding [Term] id: CCO:F0004694 name: NADH dehydrogenase (plastoquinone) activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol." [EC:1.6.99.6, GOC:mah] synonym: "NADH:plastoquinone reductase activity" EXACT [] xref: GO:0030024 xref: GO:0031679 is_a: CCO:F0007489 ! NADH dehydrogenase (quinone) activity [Term] id: CCO:F0004695 name: G-protein beta-subunit binding namespace: molecular_function def: "Interacting selectively with a G-protein beta subunit." [GOC:mah] synonym: "G-beta protein subunit binding" EXACT [] xref: GO:0031681 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004696 name: G-protein gamma-subunit binding namespace: molecular_function def: "Interacting selectively with a G-protein gamma subunit." [GOC:mah] synonym: "G-gamma protein subunit binding" EXACT [] xref: GO:0031682 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004697 name: G-protein beta/gamma-subunit binding namespace: molecular_function def: "Interacting selectively with a complex of G-protein beta/gamma subunits." [GOC:nln] xref: GO:0031683 is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0004698 name: adenosine receptor binding namespace: molecular_function def: "Interacting selectively with an adenosine receptor." [GOC:mah, GOC:nln] synonym: "adenosine receptor ligand" NARROW [] xref: GO:0031685 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004699 name: A1 adenosine receptor binding namespace: molecular_function def: "Interacting selectively with an A1 adenosine receptor." [GOC:mah, GOC:nln] synonym: "A1 adenosine receptor ligand" NARROW [] xref: GO:0031686 is_a: CCO:F0004698 ! adenosine receptor binding [Term] id: CCO:F0004700 name: A2A adenosine receptor binding namespace: molecular_function def: "Interacting selectively with an A2A adenosine receptor." [GOC:mah, GOC:nln] synonym: "A2A adenosine receptor ligand" NARROW [] xref: GO:0031687 is_a: CCO:F0004698 ! adenosine receptor binding [Term] id: CCO:F0004701 name: A2B adenosine receptor binding namespace: molecular_function def: "Interacting selectively with an A2B adenosine receptor." [GOC:mah, GOC:nln] synonym: "A2B adenosine receptor ligand" NARROW [] xref: GO:0031688 is_a: CCO:F0004698 ! adenosine receptor binding [Term] id: CCO:F0004702 name: A3 adenosine receptor binding namespace: molecular_function def: "Interacting selectively with an A3 adenosine receptor." [GOC:mah, GOC:nln] synonym: "A3 adenosine receptor ligand" NARROW [] xref: GO:0031689 is_a: CCO:F0004698 ! adenosine receptor binding [Term] id: CCO:F0004703 name: adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with an adrenergic receptor." [GOC:mah, GOC:nln] synonym: "adrenergic receptor ligand" NARROW [] xref: GO:0031690 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004704 name: alpha-1A adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with an alpha-1A adrenergic receptor." [GOC:mah, GOC:nln] synonym: "alpha-1A adrenergic receptor ligand" NARROW [] xref: GO:0031691 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004705 name: alpha-1B adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with an alpha-1B adrenergic receptor." [GOC:mah, GOC:nln] synonym: "alpha-1B adrenergic receptor ligand" NARROW [] xref: GO:0031692 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004706 name: alpha-1D adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with an alpha-1D adrenergic receptor." [GOC:mah, GOC:nln] synonym: "alpha-1D adrenergic receptor ligand" NARROW [] xref: GO:0031693 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004707 name: alpha-2A adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with an alpha-2A adrenergic receptor." [GOC:mah, GOC:nln] synonym: "alpha-2A adrenergic receptor ligand" NARROW [] xref: GO:0031694 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004708 name: alpha-2B adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with an alpha-2B adrenergic receptor." [GOC:mah, GOC:nln] synonym: "alpha-2B adrenergic receptor ligand" NARROW [] xref: GO:0031695 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004709 name: alpha-2C adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with an alpha-2C adrenergic receptor." [GOC:mah, GOC:nln] synonym: "alpha-2C adrenergic receptor ligand" NARROW [] xref: GO:0031696 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004710 name: beta-1 adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with a beta-1 adrenergic receptor." [GOC:mah, GOC:nln] synonym: "beta-1 adrenergic receptor ligand" NARROW [] xref: GO:0031697 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004711 name: beta-2 adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with a beta-2 adrenergic receptor." [GOC:mah, GOC:nln] synonym: "beta-2 adrenergic receptor ligand" NARROW [] xref: GO:0031698 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004712 name: beta-3 adrenergic receptor binding namespace: molecular_function def: "Interacting selectively with a beta-3 adrenergic receptor." [GOC:mah, GOC:nln] synonym: "beta-3 adrenergic receptor ligand" NARROW [] xref: GO:0031699 is_a: CCO:F0004703 ! adrenergic receptor binding [Term] id: CCO:F0004713 name: adrenomedullin receptor binding namespace: molecular_function def: "Interacting selectively with an adrenomedullin receptor." [GOC:mah, GOC:nln] synonym: "adrenomedullin receptor ligand" NARROW [] xref: GO:0031700 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004714 name: angiotensin receptor binding namespace: molecular_function def: "Interacting selectively with an angiotensin receptor." [GOC:mah, GOC:nln] synonym: "angiotensin receptor ligand" NARROW [] xref: GO:0031701 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004715 name: type 1 angiotensin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 angiotensin receptor." [GOC:mah, GOC:nln] synonym: "AT1 receptor binding" EXACT [] synonym: "type 1 angiotensin receptor ligand" NARROW [] xref: GO:0031702 is_a: CCO:F0004714 ! angiotensin receptor binding [Term] id: CCO:F0004716 name: type 2 angiotensin receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 angiotensin receptor." [GOC:mah, GOC:nln] synonym: "AT2 receptor binding" EXACT [] synonym: "type 2 angiotensin receptor ligand" NARROW [] xref: GO:0031703 is_a: CCO:F0004714 ! angiotensin receptor binding [Term] id: CCO:F0004717 name: apelin receptor binding namespace: molecular_function def: "Interacting selectively with an apelin receptor." [GOC:mah, GOC:nln, GOC:vp, PMID:12787050] synonym: "apelin receptor ligand" NARROW [] synonym: "APJ receptor binding" EXACT [] xref: GO:0031704 xref: GO:0042569 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004718 name: bombesin receptor binding namespace: molecular_function def: "Interacting selectively with a bombesin receptor." [GOC:mah, GOC:nln] synonym: "bombesin receptor ligand" NARROW [] xref: GO:0031705 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004719 name: subtype 3 bombesin receptor binding namespace: molecular_function def: "Interacting selectively with a subtype 3 bombesin receptor." [GOC:mah, GOC:nln] synonym: "subtype 3 bombesin receptor ligand" NARROW [] xref: GO:0031706 is_a: CCO:F0004718 ! bombesin receptor binding [Term] id: CCO:F0004720 name: endothelin A receptor binding namespace: molecular_function def: "Interacting selectively with an endothelin A receptor." [GOC:mah, GOC:nln] synonym: "endothelin A receptor ligand" NARROW [] synonym: "endothelin-1 receptor binding" EXACT [] xref: GO:0031707 is_a: CCO:F0004718 ! bombesin receptor binding [Term] id: CCO:F0004721 name: endothelin B receptor binding namespace: molecular_function def: "Interacting selectively with an endothelin B receptor." [GOC:mah, GOC:nln] synonym: "endothelin B receptor ligand" NARROW [] xref: GO:0031708 is_a: CCO:F0004718 ! bombesin receptor binding [Term] id: CCO:F0004722 name: gastrin-releasing peptide receptor binding namespace: molecular_function def: "Interacting selectively with a gastrin-releasing peptide receptor." [GOC:mah, GOC:nln] synonym: "gastrin-releasing peptide receptor ligand" NARROW [] synonym: "GRP receptor binding" EXACT [] xref: GO:0031709 is_a: CCO:F0004718 ! bombesin receptor binding [Term] id: CCO:F0004723 name: neuromedin B receptor binding namespace: molecular_function def: "Interacting selectively with a neuromedin B receptor." [GOC:mah, GOC:nln] synonym: "neuromedin B receptor ligand" NARROW [] xref: GO:0031710 is_a: CCO:F0004718 ! bombesin receptor binding [Term] id: CCO:F0004724 name: bradykinin receptor binding namespace: molecular_function def: "Interacting selectively with a bradykinin receptor." [GOC:mah, GOC:nln] synonym: "bradykinin receptor ligand" NARROW [] xref: GO:0031711 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004725 name: B1 bradykinin receptor binding namespace: molecular_function def: "Interacting selectively with a B1 bradykinin receptor." [GOC:mah, GOC:nln] synonym: "B1 bradykinin receptor ligand" NARROW [] xref: GO:0031712 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004726 name: B2 bradykinin receptor binding namespace: molecular_function def: "Interacting selectively with a B2 bradykinin receptor." [GOC:mah, GOC:nln] synonym: "B2 bradykinin receptor ligand" NARROW [] xref: GO:0031713 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004727 name: C5a anaphylatoxin chemotactic receptor binding namespace: molecular_function def: "Interacting selectively with a C5a anaphylatoxin chemotactic receptor." [GOC:mah, GOC:nln] synonym: "C5a anaphylatoxin chemotactic receptor ligand" NARROW [] xref: GO:0031714 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004728 name: C5L2 anaphylatoxin chemotactic receptor binding namespace: molecular_function def: "Interacting selectively with a C5L2 anaphylatoxin chemotactic receptor." [GOC:mah, GOC:nln] synonym: "C5L2 anaphylatoxin chemotactic receptor ligand" NARROW [] xref: GO:0031715 is_a: CCO:F0004727 ! C5a anaphylatoxin chemotactic receptor binding [Term] id: CCO:F0004729 name: calcitonin receptor binding namespace: molecular_function def: "Interacting selectively with a calcitonin receptor." [GOC:mah, GOC:nln] synonym: "calcitonin receptor ligand" NARROW [] xref: GO:0031716 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004730 name: cannabinoid receptor binding namespace: molecular_function def: "Interacting selectively with a cannabinoid receptor." [GOC:mah, GOC:nln] synonym: "cannabinoid receptor ligand" NARROW [] xref: GO:0031717 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004731 name: type 1 cannabinoid receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 cannabinoid receptor." [GOC:mah, GOC:nln] synonym: "type 1 cannabinoid receptor ligand" NARROW [] xref: GO:0031718 is_a: CCO:F0004730 ! cannabinoid receptor binding [Term] id: CCO:F0004732 name: type 2 cannabinoid receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 cannabinoid receptor." [GOC:mah, GOC:nln] synonym: "type 2 cannabinoid receptor ligand" NARROW [] xref: GO:0031719 is_a: CCO:F0004730 ! cannabinoid receptor binding [Term] id: CCO:F0004733 name: haptoglobin binding namespace: molecular_function def: "Interacting selectively with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0031720 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004734 name: hemoglobin alpha binding namespace: molecular_function def: "Interacting selectively with a hemoglobin alpha chain." [GOC:mah] xref: GO:0031721 is_a: CCO:F0004445 ! hemoglobin binding [Term] id: CCO:F0004735 name: hemoglobin beta binding namespace: molecular_function def: "Interacting selectively with a hemoglobin beta chain." [GOC:mah] xref: GO:0031722 is_a: CCO:F0004445 ! hemoglobin binding [Term] id: CCO:F0004736 name: CXCR4 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CXCR4 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CXCR4 chemokine receptor ligand" NARROW [] synonym: "stromal cell-derived factor 1 receptor binding" EXACT [] xref: GO:0031723 is_a: CCO:F0006097 ! CXCR chemokine receptor binding [Term] id: CCO:F0004737 name: CXCR5 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CXCR5 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CXCR5 chemokine receptor ligand" NARROW [] synonym: "type 1 Burkitt's lymphoma receptor binding" EXACT [] xref: GO:0031724 is_a: CCO:F0006097 ! CXCR chemokine receptor binding [Term] id: CCO:F0004738 name: CXCR6 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CXCR6 chemokine receptor." [GOC:mah, GOC:nln] synonym: "bonzo receptor binding" EXACT [] synonym: "CXCR6 chemokine receptor ligand" NARROW [] synonym: "STRL33 receptor binding" EXACT [] xref: GO:0031725 is_a: CCO:F0006097 ! CXCR chemokine receptor binding [Term] id: CCO:F0004739 name: CCR1 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR1 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR1 chemokine receptor ligand" NARROW [] synonym: "macrophage inflammatory protein-1 alpha receptor binding" EXACT [] xref: GO:0031726 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004740 name: CCR2 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR2 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR2 chemokine receptor ligand" NARROW [] synonym: "monocyte chemoattractant protein 1 receptor binding" EXACT [] xref: GO:0031727 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004741 name: CCR3 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR3 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR3 chemokine receptor ligand" NARROW [] synonym: "eosinophil eotaxin receptor binding" EXACT [] xref: GO:0031728 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004742 name: CCR4 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR4 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR4 chemokine receptor ligand" NARROW [] xref: GO:0031729 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004743 name: CCR5 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR5 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR5 chemokine receptor ligand" NARROW [] xref: GO:0031730 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004744 name: CCR6 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR6 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR6 chemokine receptor ligand" NARROW [] synonym: "LARC receptor binding" EXACT [] xref: GO:0031731 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004745 name: CCR7 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR7 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR7 chemokine receptor ligand" NARROW [] synonym: "MIP-3 beta receptor binding" EXACT [] synonym: "type 1 EBV-induced G-protein coupled receptor binding" EXACT [] xref: GO:0031732 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004746 name: CCR8 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR8 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR8 chemokine receptor ligand" NARROW [] xref: GO:0031733 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004747 name: CCR9 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR9 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR9 chemokine receptor ligand" NARROW [] xref: GO:0031734 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004748 name: CCR10 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR10 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR10 chemokine receptor ligand" NARROW [] xref: GO:0031735 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004749 name: CCR11 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR11 chemokine receptor." [GOC:mah, GOC:nln] synonym: "CCR11 chemokine receptor ligand" NARROW [] xref: GO:0031736 is_a: CCO:F0007302 ! CCR chemokine receptor binding [Term] id: CCO:F0004750 name: CX3C chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CX3C chemokine receptor." [GOC:mah, GOC:nln] synonym: "CX3C chemokine receptor ligand" NARROW [] synonym: "fractalkine receptor binding" EXACT [] xref: GO:0031737 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004751 name: XCR1 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a XCR1 chemokine receptor." [GOC:mah, GOC:nln] synonym: "lymphotactin receptor binding" EXACT [] synonym: "XCR1 chemokine receptor ligand" NARROW [] xref: GO:0031738 is_a: CCO:F0005665 ! chemokine receptor binding [Term] id: CCO:F0004752 name: cholecystokinin receptor binding namespace: molecular_function def: "Interacting selectively with a cholecystokinin receptor." [GOC:mah, GOC:nln] synonym: "cholecystokinin receptor ligand" NARROW [] xref: GO:0031739 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004753 name: type A cholecystokinin receptor binding namespace: molecular_function def: "Interacting selectively with a type A cholecystokinin receptor." [GOC:mah, GOC:nln] synonym: "type A cholecystokinin receptor ligand" NARROW [] xref: GO:0031740 is_a: CCO:F0004752 ! cholecystokinin receptor binding [Term] id: CCO:F0004754 name: type B gastrin/cholecystokinin receptor binding namespace: molecular_function def: "Interacting selectively with a type B gastrin/cholecystokinin receptor." [GOC:mah, GOC:nln] synonym: "type B gastrin/cholecystokinin receptor ligand" NARROW [] xref: GO:0031741 is_a: CCO:F0004752 ! cholecystokinin receptor binding [Term] id: CCO:F0004755 name: corticotropin releasing factor receptor binding namespace: molecular_function def: "Interacting selectively with a corticotropin releasing factor receptor." [GOC:mah, GOC:nln] synonym: "corticotropin releasing factor receptor ligand" NARROW [] xref: GO:0031742 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004756 name: type 1 corticotropin releasing factor receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 corticotropin releasing factor receptor." [GOC:mah, GOC:nln] synonym: "type 1 corticotropin releasing factor receptor ligand" NARROW [] xref: GO:0031743 is_a: CCO:F0004755 ! corticotropin releasing factor receptor binding [Term] id: CCO:F0004757 name: type 2 corticotropin releasing factor receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 corticotropin releasing factor receptor." [GOC:mah, GOC:nln] synonym: "type 2 corticotropin releasing factor receptor ligand" NARROW [] xref: GO:0031744 is_a: CCO:F0004755 ! corticotropin releasing factor receptor binding [Term] id: CCO:F0004758 name: cysteinyl leukotriene receptor binding namespace: molecular_function def: "Interacting selectively with a cysteinyl leukotriene receptor." [GOC:mah, GOC:nln] synonym: "cysteinyl leukotriene receptor ligand" NARROW [] xref: GO:0031745 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004759 name: type 1 cysteinyl leukotriene receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 cysteinyl leukotriene receptor." [GOC:mah, GOC:nln] synonym: "type 1 cysteinyl leukotriene receptor ligand" NARROW [] xref: GO:0031746 is_a: CCO:F0004758 ! cysteinyl leukotriene receptor binding [Term] id: CCO:F0004760 name: type 2 cysteinyl leukotriene receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 cysteinyl leukotriene receptor." [GOC:mah, GOC:nln] synonym: "type 2 cysteinyl leukotriene receptor ligand" NARROW [] xref: GO:0031747 is_a: CCO:F0004758 ! cysteinyl leukotriene receptor binding [Term] id: CCO:F0004761 name: D1 dopamine receptor binding namespace: molecular_function def: "Interacting selectively with a D1 dopamine receptor." [GOC:mah, GOC:nln] synonym: "D1 dopamine receptor ligand" NARROW [] synonym: "D1A dopamine receptor binding" EXACT [] xref: GO:0031748 is_a: CCO:F0008009 ! dopamine receptor binding [Term] id: CCO:F0004762 name: D2 dopamine receptor binding namespace: molecular_function def: "Interacting selectively with a D2 dopamine receptor." [GOC:mah, GOC:nln] synonym: "D2 dopamine receptor ligand" NARROW [] xref: GO:0031749 is_a: CCO:F0008009 ! dopamine receptor binding [Term] id: CCO:F0004763 name: D3 dopamine receptor binding namespace: molecular_function def: "Interacting selectively with a D3 dopamine receptor." [GOC:mah, GOC:nln] synonym: "D3 dopamine receptor ligand" NARROW [] xref: GO:0031750 is_a: CCO:F0008009 ! dopamine receptor binding [Term] id: CCO:F0004764 name: D4 dopamine receptor binding namespace: molecular_function def: "Interacting selectively with a D4 dopamine receptor." [GOC:mah, GOC:nln] synonym: "D4 dopamine receptor ligand" NARROW [] xref: GO:0031751 is_a: CCO:F0008009 ! dopamine receptor binding [Term] id: CCO:F0004765 name: D5 dopamine receptor binding namespace: molecular_function def: "Interacting selectively with a D5 dopamine receptor." [GOC:mah, GOC:nln] synonym: "D1B dopamine receptor binding" EXACT [] synonym: "D5 dopamine receptor ligand" NARROW [] xref: GO:0031752 is_a: CCO:F0008009 ! dopamine receptor binding [Term] id: CCO:F0004766 name: endothelial differentiation G-protein coupled receptor binding namespace: molecular_function def: "Interacting selectively with an endothelial differentiation G-protein coupled receptor." [GOC:mah, GOC:nln] synonym: "endothelial differentiation G-protein coupled receptor ligand" NARROW [] xref: GO:0031753 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004767 name: Edg-1 sphingosine 1-phosphate receptor binding namespace: molecular_function def: "Interacting selectively with an Edg-1 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] synonym: "Edg-1 sphingosine 1-phosphate receptor ligand" NARROW [] xref: GO:0031754 is_a: CCO:F0004766 ! endothelial differentiation G-protein coupled receptor binding [Term] id: CCO:F0004768 name: Edg-2 lysophosphatidic acid receptor binding namespace: molecular_function def: "Interacting selectively with an Edg-2 lysophosphatidic acid receptor." [GOC:mah, GOC:nln] synonym: "Edg-2 lysophosphatidic acid receptor ligand" NARROW [] synonym: "LPA1 receptor binding" EXACT [] xref: GO:0031755 is_a: CCO:F0004766 ! endothelial differentiation G-protein coupled receptor binding [Term] id: CCO:F0004769 name: Edg-3 sphingosine 1-phosphate receptor binding namespace: molecular_function def: "Interacting selectively with an Edg-3 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] synonym: "Edg-3 sphingosine 1-phosphate receptor ligand" NARROW [] xref: GO:0031756 is_a: CCO:F0004766 ! endothelial differentiation G-protein coupled receptor binding [Term] id: CCO:F0004770 name: Edg-4 lysophosphatidic acid receptor binding namespace: molecular_function def: "Interacting selectively with an Edg-4 lysophosphatidic acid receptor." [GOC:mah, GOC:nln] synonym: "Edg-4 lysophosphatidic acid receptor ligand" NARROW [] synonym: "LPA2 receptor binding" EXACT [] xref: GO:0031757 is_a: CCO:F0004766 ! endothelial differentiation G-protein coupled receptor binding [Term] id: CCO:F0004771 name: Edg-5 sphingosine 1-phosphate receptor binding namespace: molecular_function def: "Interacting selectively with an Edg-5 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] synonym: "Edg-5 sphingosine 1-phosphate receptor ligand" NARROW [] xref: GO:0031758 is_a: CCO:F0004766 ! endothelial differentiation G-protein coupled receptor binding [Term] id: CCO:F0004772 name: Edg-6 sphingosine 1-phosphate receptor binding namespace: molecular_function def: "Interacting selectively with an Edg-6 sphingosine 1-phosphate receptor." [GOC:mah, GOC:nln] synonym: "Edg-6 sphingosine 1-phosphate receptor ligand" NARROW [] xref: GO:0031759 is_a: CCO:F0004766 ! endothelial differentiation G-protein coupled receptor binding [Term] id: CCO:F0004773 name: Edg-7 lysophosphatidic acid receptor binding namespace: molecular_function def: "Interacting selectively with an Edg-7 lysophosphatidic acid receptor." [GOC:mah, GOC:nln] synonym: "Edg-7 lysophosphatidic acid receptor ligand" NARROW [] synonym: "LPA3 receptor binding" EXACT [] xref: GO:0031760 is_a: CCO:F0004766 ! endothelial differentiation G-protein coupled receptor binding [Term] id: CCO:F0004774 name: fMet-Leu-Phe receptor binding namespace: molecular_function def: "Interacting selectively with a fMet-Leu-Phe receptor." [GOC:mah, GOC:nln] synonym: "fMet-Leu-Phe receptor ligand" NARROW [] synonym: "N-formyl peptide receptor binding" EXACT [] xref: GO:0031761 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004775 name: follicle stimulating hormone receptor binding namespace: molecular_function def: "Interacting selectively with a follicle stimulating hormone receptor." [GOC:mah, GOC:nln] synonym: "follicle stimulating hormone receptor ligand" NARROW [] xref: GO:0031762 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004776 name: galanin receptor binding namespace: molecular_function def: "Interacting selectively with a galanin receptor." [GOC:mah, GOC:nln] synonym: "galanin receptor ligand" NARROW [] xref: GO:0031763 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004777 name: type 1 galanin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 galanin receptor." [GOC:mah, GOC:nln] synonym: "type 1 galanin receptor ligand" NARROW [] xref: GO:0031764 is_a: CCO:F0004776 ! galanin receptor binding [Term] id: CCO:F0004778 name: type 2 galanin receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 galanin receptor." [GOC:mah, GOC:nln] synonym: "type 2 galanin receptor ligand" NARROW [] xref: GO:0031765 is_a: CCO:F0004776 ! galanin receptor binding [Term] id: CCO:F0004779 name: type 3 galanin receptor binding namespace: molecular_function def: "Interacting selectively with a type 3 galanin receptor." [GOC:mah, GOC:nln] synonym: "type 3 galanin receptor ligand" NARROW [] xref: GO:0031766 is_a: CCO:F0004776 ! galanin receptor binding [Term] id: CCO:F0004780 name: gastric inhibitory polypeptide receptor binding namespace: molecular_function def: "Interacting selectively with a gastric inhibitory polypeptide receptor." [GOC:mah, GOC:nln] synonym: "gastric inhibitory polypeptide receptor ligand" NARROW [] xref: GO:0031767 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004781 name: ghrelin receptor binding namespace: molecular_function def: "Interacting selectively with a ghrelin receptor." [GOC:mah, GOC:nln] synonym: "ghrelin receptor ligand" NARROW [] synonym: "type 1 growth hormone secretagogue GH-releasing peptide receptor binding" EXACT [] xref: GO:0031768 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004782 name: glucagon receptor binding namespace: molecular_function def: "Interacting selectively with a glucagon receptor." [GOC:mah, GOC:nln] synonym: "glucagon receptor ligand" NARROW [] xref: GO:0031769 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004783 name: growth hormone-releasing hormone receptor binding namespace: molecular_function def: "Interacting selectively with a growth hormone-releasing hormone receptor." [GOC:mah, GOC:nln] synonym: "growth hormone-releasing hormone receptor ligand" NARROW [] xref: GO:0031770 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004784 name: type 1 hypocretin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 hypocretin receptor." [GOC:mah, GOC:nln] synonym: "type 1 hypocretin receptor ligand" NARROW [] synonym: "type 1 orexin receptor binding" EXACT [] xref: GO:0031771 is_a: CCO:F0005660 ! hypocretin receptor binding [Term] id: CCO:F0004785 name: type 2 hypocretin receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 hypocretin receptor." [GOC:mah, GOC:nln] synonym: "type 2 hypocretin receptor ligand" NARROW [] synonym: "type 2 orexin receptor binding" EXACT [] xref: GO:0031772 is_a: CCO:F0005660 ! hypocretin receptor binding [Term] id: CCO:F0004786 name: kisspeptin receptor binding namespace: molecular_function def: "Interacting selectively with a kisspeptin receptor." [GOC:mah, GOC:nln] synonym: "G-protein coupled receptor 54 binding" EXACT [] synonym: "hOT7T175 receptor binding" EXACT [] synonym: "hypogonadotropin-1 receptor binding" EXACT [] synonym: "KiSS-1 receptor binding" EXACT [] synonym: "kisspeptin receptor ligand" NARROW [] synonym: "metastin receptor binding" EXACT [] xref: GO:0031773 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004787 name: leukotriene receptor binding namespace: molecular_function def: "Interacting selectively with a leukotriene receptor." [GOC:mah, GOC:nln] synonym: "leukotriene receptor ligand" NARROW [] xref: GO:0031774 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004788 name: lutropin-choriogonadotropic hormone receptor binding namespace: molecular_function def: "Interacting selectively with a lutropin-choriogonadotropic hormone receptor." [GOC:mah, GOC:nln] synonym: "lutropin-choriogonadotropic hormone receptor ligand" NARROW [] xref: GO:0031775 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004789 name: melanin-concentrating hormone receptor binding namespace: molecular_function def: "Interacting selectively with a melanin-concentrating hormone receptor." [GOC:mah, GOC:nln] synonym: "melanin-concentrating hormone receptor ligand" NARROW [] xref: GO:0031776 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004790 name: type 1 melanin-concentrating hormone receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 melanin-concentrating hormone receptor." [GOC:mah, GOC:nln] synonym: "type 1 melanin-concentrating hormone receptor ligand" NARROW [] xref: GO:0031777 is_a: CCO:F0004789 ! melanin-concentrating hormone receptor binding [Term] id: CCO:F0004791 name: type 2 melanin-concentrating hormone receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 melanin-concentrating hormone receptor." [GOC:mah, GOC:nln] synonym: "type 2 melanin-concentrating hormone receptor ligand" NARROW [] xref: GO:0031778 is_a: CCO:F0004789 ! melanin-concentrating hormone receptor binding [Term] id: CCO:F0004792 name: melanocortin receptor binding namespace: molecular_function def: "Interacting selectively with a melanocortin receptor." [GOC:mah, GOC:nln] synonym: "melanocortin receptor ligand" NARROW [] xref: GO:0031779 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004793 name: adrenocorticotropin hormone receptor binding namespace: molecular_function def: "Interacting selectively with an adrenocorticotropin hormone receptor." [GOC:dph, GOC:mah, GOC:nln] synonym: "ACTH receptor binding" EXACT [] synonym: "adrenocorticotropic hormone receptor ligand" NARROW [] xref: GO:0031780 is_a: CCO:F0004792 ! melanocortin receptor binding [Term] id: CCO:F0004794 name: type 3 melanocortin receptor binding namespace: molecular_function def: "Interacting selectively with a type 3 melanocortin receptor." [GOC:mah, GOC:nln] synonym: "type 3 melanocortin receptor ligand" NARROW [] xref: GO:0031781 is_a: CCO:F0004792 ! melanocortin receptor binding [Term] id: CCO:F0004795 name: type 4 melanocortin receptor binding namespace: molecular_function def: "Interacting selectively with a type 4 melanocortin receptor." [GOC:mah, GOC:nln] synonym: "type 4 melanocortin receptor ligand" NARROW [] xref: GO:0031782 is_a: CCO:F0004792 ! melanocortin receptor binding [Term] id: CCO:F0004796 name: type 5 melanocortin receptor binding namespace: molecular_function def: "Interacting selectively with a type 5 melanocortin receptor." [GOC:mah, GOC:nln] synonym: "type 5 melanocortin receptor ligand" NARROW [] xref: GO:0031783 is_a: CCO:F0004792 ! melanocortin receptor binding [Term] id: CCO:F0004797 name: melatonin receptor binding namespace: molecular_function def: "Interacting selectively with a melatonin receptor." [GOC:mah, GOC:nln] synonym: "melatonin receptor ligand" NARROW [] xref: GO:0031784 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004798 name: type 1A melatonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1A melatonin receptor." [GOC:mah, GOC:nln] synonym: "type 1A melatonin receptor ligand" NARROW [] xref: GO:0031785 is_a: CCO:F0004797 ! melatonin receptor binding [Term] id: CCO:F0004799 name: type 1B melatonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1B melatonin receptor." [GOC:mah, GOC:nln] synonym: "type 1B melatonin receptor ligand" NARROW [] xref: GO:0031786 is_a: CCO:F0004797 ! melatonin receptor binding [Term] id: CCO:F0004800 name: H9 melatonin receptor binding namespace: molecular_function def: "Interacting selectively with a H9 melatonin receptor." [GOC:mah, GOC:nln] synonym: "H9 melatonin receptor ligand" NARROW [] xref: GO:0031787 is_a: CCO:F0004797 ! melatonin receptor binding [Term] id: CCO:F0004801 name: motilin receptor binding namespace: molecular_function def: "Interacting selectively with a motilin receptor." [GOC:mah, GOC:nln] synonym: "motilin receptor ligand" NARROW [] xref: GO:0031788 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004802 name: muscarinic acetylcholine receptor binding namespace: molecular_function def: "Interacting selectively with a muscarinic acetylcholine receptor." [GOC:mah, GOC:nln] synonym: "muscarinic acetylcholine receptor ligand" NARROW [] xref: GO:0031789 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004803 name: M1 muscarinic acetylcholine receptor binding namespace: molecular_function def: "Interacting selectively with a M1 muscarinic acetylcholine receptor." [GOC:mah, GOC:nln] synonym: "M1 muscarinic acetylcholine receptor ligand" NARROW [] xref: GO:0031790 is_a: CCO:F0004802 ! muscarinic acetylcholine receptor binding [Term] id: CCO:F0004804 name: M2 muscarinic acetylcholine receptor binding namespace: molecular_function def: "Interacting selectively with a M2 muscarinic acetylcholine receptor." [GOC:mah, GOC:nln] synonym: "M2 muscarinic acetylcholine receptor ligand" NARROW [] xref: GO:0031791 is_a: CCO:F0004802 ! muscarinic acetylcholine receptor binding [Term] id: CCO:F0004805 name: M3 muscarinic acetylcholine receptor binding namespace: molecular_function def: "Interacting selectively with a M3 muscarinic acetylcholine receptor." [GOC:mah, GOC:nln] synonym: "M3 muscarinic acetylcholine receptor ligand" NARROW [] xref: GO:0031792 is_a: CCO:F0004802 ! muscarinic acetylcholine receptor binding [Term] id: CCO:F0004806 name: M4 muscarinic acetylcholine receptor binding namespace: molecular_function def: "Interacting selectively with a M4 muscarinic acetylcholine receptor." [GOC:mah, GOC:nln] synonym: "M4 muscarinic acetylcholine receptor ligand" NARROW [] xref: GO:0031793 is_a: CCO:F0004802 ! muscarinic acetylcholine receptor binding [Term] id: CCO:F0004807 name: M5 muscarinic acetylcholine receptor binding namespace: molecular_function def: "Interacting selectively with a M5 muscarinic acetylcholine receptor." [GOC:mah, GOC:nln] synonym: "M5 muscarinic acetylcholine receptor ligand" NARROW [] xref: GO:0031794 is_a: CCO:F0004802 ! muscarinic acetylcholine receptor binding [Term] id: CCO:F0004808 name: metabotropic GABA receptor binding namespace: molecular_function def: "Interacting selectively with a metabotropic GABA receptor." [GOC:mah, GOC:nln] synonym: "GABAB receptor binding" EXACT [] synonym: "metabotropic GABA receptor ligand" NARROW [] xref: GO:0031795 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004809 name: type 1 metabotropic GABA receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 metabotropic GABA receptor." [GOC:mah, GOC:nln] synonym: "type 1 metabotropic GABA receptor ligand" NARROW [] xref: GO:0031796 is_a: CCO:F0004808 ! metabotropic GABA receptor binding [Term] id: CCO:F0004810 name: type 2 metabotropic GABA receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 metabotropic GABA receptor." [GOC:mah, GOC:nln] synonym: "type 2 metabotropic GABA receptor ligand" NARROW [] xref: GO:0031797 is_a: CCO:F0004808 ! metabotropic GABA receptor binding [Term] id: CCO:F0004811 name: type 1 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 1 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031798 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004812 name: type 2 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 2 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031799 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004813 name: type 3 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 3 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 3 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031800 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004814 name: type 4 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 4 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 4 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031801 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004815 name: type 5 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 5 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 5 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031802 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004816 name: type 6 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 6 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 6 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031803 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004817 name: type 7 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 7 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 7 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031804 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004818 name: type 8 metabotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a type 8 metabotropic glutamate receptor." [GOC:mah, GOC:nln] synonym: "type 8 metabotropic glutamate receptor ligand" NARROW [] xref: GO:0031805 is_a: CCO:F0005584 ! metabotropic glutatmate receptor binding [Term] id: CCO:F0004819 name: metabotropic histamine receptor binding namespace: molecular_function def: "Interacting selectively with a metabotropic histamine receptor." [GOC:mah, GOC:nln] synonym: "metabotropic histamine receptor ligand" NARROW [] xref: GO:0031806 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004820 name: H1 histamine receptor binding namespace: molecular_function def: "Interacting selectively with a H1 histamine receptor." [GOC:mah, GOC:nln] synonym: "H1 histamine receptor ligand" NARROW [] xref: GO:0031807 is_a: CCO:F0004819 ! metabotropic histamine receptor binding [Term] id: CCO:F0004821 name: H2 histamine receptor binding namespace: molecular_function def: "Interacting selectively with a H2 histamine receptor." [GOC:mah, GOC:nln] synonym: "H2 histamine receptor ligand" NARROW [] xref: GO:0031808 is_a: CCO:F0004819 ! metabotropic histamine receptor binding [Term] id: CCO:F0004822 name: H3 histamine receptor binding namespace: molecular_function def: "Interacting selectively with a H3 histamine receptor." [GOC:mah, GOC:nln] synonym: "H3 histamine receptor ligand" NARROW [] xref: GO:0031809 is_a: CCO:F0004819 ! metabotropic histamine receptor binding [Term] id: CCO:F0004823 name: H4 histamine receptor binding namespace: molecular_function def: "Interacting selectively with a H4 histamine receptor." [GOC:mah, GOC:nln] synonym: "H4 histamine receptor ligand" NARROW [] xref: GO:0031810 is_a: CCO:F0004819 ! metabotropic histamine receptor binding [Term] id: CCO:F0004824 name: metabotropic nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a metabotropic nucleotide receptor." [GOC:mah, GOC:nln] synonym: "metabotropic nucleotide receptor ligand" NARROW [] synonym: "P2Y receptor binding" EXACT [] xref: GO:0031811 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004825 name: P2Y1 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y1 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y1 nucleotide receptor ligand" NARROW [] xref: GO:0031812 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004826 name: P2Y2 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y2 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y2 nucleotide receptor ligand" NARROW [] xref: GO:0031813 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004827 name: P2Y4 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y4 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y4 nucleotide receptor ligand" NARROW [] xref: GO:0031814 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004828 name: P2Y5 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y5 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y5 nucleotide receptor ligand" NARROW [] xref: GO:0031815 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004829 name: P2Y6 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y6 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y6 nucleotide receptor ligand" NARROW [] xref: GO:0031816 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004830 name: P2Y8 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y8 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y8 nucleotide receptor ligand" NARROW [] xref: GO:0031817 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004831 name: P2Y9 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y9 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y9 nucleotide receptor ligand" NARROW [] xref: GO:0031818 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004832 name: P2Y10 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y10 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y10 nucleotide receptor ligand" NARROW [] xref: GO:0031819 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004833 name: P2Y11 nucleotide receptor binding namespace: molecular_function def: "Interacting selectively with a P2Y11 nucleotide receptor." [GOC:mah, GOC:nln] synonym: "P2Y11 nucleotide receptor ligand" NARROW [] xref: GO:0031820 is_a: CCO:F0004824 ! metabotropic nucleotide receptor binding [Term] id: CCO:F0004834 name: metabotropic serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a metabotropic serotonin receptor." [GOC:mah, GOC:nln] synonym: "metabotropic 5-hydroxytryptamine receptor binding" EXACT [] synonym: "metabotropic serotonin receptor ligand" NARROW [] xref: GO:0031821 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004835 name: type 1B serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1B serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 1B receptor binding" EXACT [] synonym: "type 1B serotonin receptor ligand" NARROW [] xref: GO:0031822 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004836 name: type 1D serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1D serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 1D receptor binding" EXACT [] synonym: "type 1D serotonin receptor ligand" NARROW [] xref: GO:0031823 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004837 name: type 1E serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1E serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 1E receptor binding" EXACT [] synonym: "type 1E serotonin receptor ligand" NARROW [] xref: GO:0031824 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004838 name: type 1F serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1F serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 1F receptor binding" EXACT [] synonym: "type 1F serotonin receptor ligand" NARROW [] xref: GO:0031825 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004839 name: type 2A serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 2A serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 2A receptor binding" EXACT [] synonym: "type 2A serotonin receptor ligand" NARROW [] xref: GO:0031826 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004840 name: type 2B serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 2B serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 2B receptor binding" EXACT [] synonym: "type 2B serotonin receptor ligand" NARROW [] xref: GO:0031827 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004841 name: type 2C serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 2C serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 2C receptor binding" EXACT [] synonym: "type 2C serotonin receptor ligand" NARROW [] xref: GO:0031828 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004842 name: type 4 serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 4 serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 4 receptor binding" EXACT [] synonym: "type 4 serotonin receptor ligand" NARROW [] xref: GO:0031829 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004843 name: type 5A serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 5A serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 5A receptor binding" EXACT [] synonym: "type 5A serotonin receptor ligand" NARROW [] xref: GO:0031830 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004844 name: type 5B serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 5B serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 5B receptor binding" EXACT [] synonym: "type 5B serotonin receptor ligand" NARROW [] xref: GO:0031831 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004845 name: type 6 serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 6 serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 6 receptor binding" EXACT [] synonym: "type 6 serotonin receptor ligand" NARROW [] xref: GO:0031832 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004846 name: type 7 serotonin receptor binding namespace: molecular_function def: "Interacting selectively with a type 7 serotonin receptor." [GOC:mah, GOC:nln] synonym: "5-hydroxytryptamine 7 receptor binding" EXACT [] synonym: "type 7 serotonin receptor ligand" NARROW [] xref: GO:0031833 is_a: CCO:F0004834 ! metabotropic serotonin receptor binding [Term] id: CCO:F0004847 name: neurokinin receptor binding namespace: molecular_function def: "Interacting selectively with a neurokinin receptor." [GOC:mah, GOC:nln] synonym: "neurokinin receptor ligand" NARROW [] xref: GO:0031834 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004848 name: substance P receptor binding namespace: molecular_function def: "Interacting selectively with a substance P receptor." [GOC:mah, GOC:nln] synonym: "neurokinin-1 receptor binding" EXACT [] synonym: "substance P receptor ligand" NARROW [] xref: GO:0031835 is_a: CCO:F0004847 ! neurokinin receptor binding [Term] id: CCO:F0004849 name: neuromedin K receptor binding namespace: molecular_function def: "Interacting selectively with a neuromedin K receptor." [GOC:mah, GOC:nln] synonym: "neurokinin-B receptor binding" EXACT [] synonym: "neuromedin K receptor ligand" NARROW [] xref: GO:0031836 is_a: CCO:F0004847 ! neurokinin receptor binding [Term] id: CCO:F0004850 name: substance K receptor binding namespace: molecular_function def: "Interacting selectively with a substance K receptor." [GOC:mah, GOC:nln] synonym: "neurokinin-A receptor binding" EXACT [] synonym: "substance K receptor ligand" NARROW [] xref: GO:0031837 is_a: CCO:F0004847 ! neurokinin receptor binding [Term] id: CCO:F0004851 name: type 1 neuromedin U receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 neuromedin U receptor." [GOC:mah, GOC:nln] synonym: "type 1 neuromedin U receptor ligand" NARROW [] xref: GO:0031839 is_a: CCO:F0005745 ! neuromedin U receptor binding [Term] id: CCO:F0004852 name: type 2 neuromedin U receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 neuromedin U receptor." [GOC:mah, GOC:nln] synonym: "type 2 neuromedin U receptor ligand" NARROW [] xref: GO:0031840 is_a: CCO:F0005745 ! neuromedin U receptor binding [Term] id: CCO:F0004853 name: neuropeptide Y receptor binding namespace: molecular_function def: "Interacting selectively with a neuropeptide Y receptor." [GOC:mah, GOC:nln] synonym: "neuropeptide Y receptor ligand" NARROW [] synonym: "NPY receptor binding" EXACT [] xref: GO:0031841 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004854 name: type 1 neuropeptide Y receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 neuropeptide Y receptor." [GOC:mah, GOC:nln] synonym: "type 1 neuropeptide Y receptor ligand" NARROW [] xref: GO:0031842 is_a: CCO:F0004853 ! neuropeptide Y receptor binding [Term] id: CCO:F0004855 name: type 2 neuropeptide Y receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 neuropeptide Y receptor." [GOC:mah, GOC:nln] synonym: "type 2 neuropeptide Y receptor ligand" NARROW [] xref: GO:0031843 is_a: CCO:F0004853 ! neuropeptide Y receptor binding [Term] id: CCO:F0004856 name: type 4 neuropeptide Y receptor binding namespace: molecular_function def: "Interacting selectively with a type 4 neuropeptide Y receptor." [GOC:mah, GOC:nln] synonym: "pancreatic polypeptide receptor binding" EXACT [] synonym: "type 4 neuropeptide Y receptor ligand" NARROW [] xref: GO:0031844 is_a: CCO:F0004853 ! neuropeptide Y receptor binding [Term] id: CCO:F0004857 name: type 5 neuropeptide Y receptor binding namespace: molecular_function def: "Interacting selectively with a type 5 neuropeptide Y receptor." [GOC:mah, GOC:nln] synonym: "type 5 neuropeptide Y receptor ligand" NARROW [] xref: GO:0031845 is_a: CCO:F0004853 ! neuropeptide Y receptor binding [Term] id: CCO:F0004858 name: neurotensin receptor binding namespace: molecular_function def: "Interacting selectively with a neurotensin receptor." [GOC:mah, GOC:nln] synonym: "neurotensin receptor ligand" NARROW [] xref: GO:0031846 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004859 name: type 1 neurotensin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 neurotensin receptor." [GOC:mah, GOC:nln] synonym: "type 1 neurotensin receptor ligand" NARROW [] xref: GO:0031847 is_a: CCO:F0004858 ! neurotensin receptor binding [Term] id: CCO:F0004860 name: olfactory receptor binding namespace: molecular_function def: "Interacting selectively with an olfactory receptor." [GOC:mah, GOC:nln] synonym: "olfactory receptor ligand" NARROW [] xref: GO:0031849 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004861 name: delta-type opioid receptor binding namespace: molecular_function def: "Interacting selectively with a delta-type opioid receptor." [GOC:mah, GOC:nln] synonym: "delta-type opioid receptor ligand" NARROW [] xref: GO:0031850 is_a: CCO:F0004691 ! opioid receptor binding [Term] id: CCO:F0004862 name: kappa-type opioid receptor binding namespace: molecular_function def: "Interacting selectively with a kappa-type opioid receptor." [GOC:mah, GOC:nln] synonym: "kappa-type opioid receptor ligand" NARROW [] xref: GO:0031851 is_a: CCO:F0004691 ! opioid receptor binding [Term] id: CCO:F0004863 name: mu-type opioid receptor binding namespace: molecular_function def: "Interacting selectively with a mu-type opioid receptor." [GOC:mah, GOC:nln] synonym: "mu-type opioid receptor ligand" NARROW [] xref: GO:0031852 is_a: CCO:F0004691 ! opioid receptor binding [Term] id: CCO:F0004864 name: nociceptin receptor binding namespace: molecular_function def: "Interacting selectively with a nociceptin receptor." [GOC:mah, GOC:nln] synonym: "nociceptin receptor ligand" NARROW [] xref: GO:0031853 is_a: CCO:F0004691 ! opioid receptor binding [Term] id: CCO:F0004865 name: orexigenic neuropeptide QRFP receptor binding namespace: molecular_function def: "Interacting selectively with an orexigenic neuropeptide QRFP receptor." [GOC:mah, GOC:nln] synonym: "orexigenic neuropeptide QRFP receptor ligand" NARROW [] xref: GO:0031854 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004866 name: oxytocin receptor binding namespace: molecular_function def: "Interacting selectively with an oxytocin receptor." [GOC:mah, GOC:nln] synonym: "oxytocin receptor ligand" NARROW [] xref: GO:0031855 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004867 name: parathyroid hormone receptor binding namespace: molecular_function def: "Interacting selectively with a parathyroid hormone receptor." [GOC:mah, GOC:nln] synonym: "parathyroid hormone receptor ligand" NARROW [] xref: GO:0031856 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004868 name: type 1 parathyroid hormone receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 parathyroid hormone receptor." [GOC:mah, GOC:nln] synonym: "type 1 parathyroid hormone receptor ligand" NARROW [] xref: GO:0031857 is_a: CCO:F0004867 ! parathyroid hormone receptor binding [Term] id: CCO:F0004869 name: pituitary adenylate cyclase-activating peptide receptor binding namespace: molecular_function def: "Interacting selectively with a pituitary adenylate cyclase-activating peptide receptor." [GOC:mah, GOC:nln] synonym: "PACAP receptor binding" EXACT [] synonym: "pituitary adenylate cyclase-activating peptide receptor ligand" NARROW [] xref: GO:0031858 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004870 name: platelet activating factor receptor binding namespace: molecular_function def: "Interacting selectively with a platelet activating factor receptor." [GOC:mah, GOC:nln] synonym: "platelet activating factor receptor ligand" NARROW [] xref: GO:0031859 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004871 name: prolactin-releasing peptide receptor binding namespace: molecular_function def: "Interacting selectively with a prolactin-releasing peptide receptor." [GOC:mah, GOC:nln] synonym: "prolactin-releasing peptide receptor ligand" NARROW [] xref: GO:0031861 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004872 name: prostanoid receptor binding namespace: molecular_function def: "Interacting selectively with a prostanoid receptor." [GOC:mah, GOC:nln] synonym: "prostanoid receptor ligand" NARROW [] xref: GO:0031862 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004873 name: prostaglandin D2 receptor binding namespace: molecular_function def: "Interacting selectively with a prostaglandin D2 receptor." [GOC:mah, GOC:nln] synonym: "prostaglandin D2 receptor ligand" NARROW [] synonym: "prostanoid DP receptor binding" EXACT [] xref: GO:0031863 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004874 name: EP1 subtype prostaglandin E2 receptor binding namespace: molecular_function def: "Interacting selectively with an EP1 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] synonym: "EP1 subtype prostaglandin E2 receptor ligand" NARROW [] synonym: "prostanoid EP1 receptor binding" EXACT [] xref: GO:0031864 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004875 name: EP2 subtype prostaglandin E2 receptor binding namespace: molecular_function def: "Interacting selectively with an EP2 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] synonym: "EP2 subtype prostaglandin E2 receptor ligand" NARROW [] synonym: "prostanoid EP2 receptor binding" EXACT [] xref: GO:0031865 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004876 name: EP3 subtype prostaglandin E2 receptor binding namespace: molecular_function def: "Interacting selectively with an EP3 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] synonym: "EP3 subtype prostaglandin E2 receptor ligand" NARROW [] synonym: "prostanoid EP3 receptor binding" EXACT [] xref: GO:0031866 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004877 name: EP4 subtype prostaglandin E2 receptor binding namespace: molecular_function def: "Interacting selectively with an EP4 subtype prostaglandin E2 receptor." [GOC:mah, GOC:nln] synonym: "EP4 subtype prostaglandin E2 receptor ligand" NARROW [] synonym: "prostanoid EP4 receptor binding" EXACT [] xref: GO:0031867 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004878 name: prostaglandin F2-alpha receptor binding namespace: molecular_function def: "Interacting selectively with a prostaglandin F2-alpha receptor." [GOC:mah, GOC:nln] synonym: "prostaglandin F2-alpha receptor ligand" NARROW [] synonym: "prostanoid FP receptor binding" EXACT [] xref: GO:0031868 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004879 name: prostacyclin receptor binding namespace: molecular_function def: "Interacting selectively with a prostacyclin receptor." [GOC:mah, GOC:nln] synonym: "prostacyclin receptor ligand" NARROW [] synonym: "prostanoid IP receptor binding" EXACT [] xref: GO:0031869 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004880 name: thromboxane A2 receptor binding namespace: molecular_function def: "Interacting selectively with a thromboxane A2 receptor." [GOC:mah, GOC:nln] synonym: "prostanoid TP receptor binding" EXACT [] synonym: "thromboxane A2 receptor ligand" NARROW [] xref: GO:0031870 is_a: CCO:F0004872 ! prostanoid receptor binding [Term] id: CCO:F0004881 name: proteinase activated receptor binding namespace: molecular_function def: "Interacting selectively with a proteinase activated receptor." [GOC:mah, GOC:nln] synonym: "proteinase activated receptor ligand" NARROW [] xref: GO:0031871 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004882 name: type 1 proteinase activated receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 proteinase activated receptor." [GOC:mah, GOC:nln] synonym: "thrombin receptor binding" EXACT [] synonym: "type 1 proteinase activated receptor ligand" NARROW [] xref: GO:0031872 is_a: CCO:F0004881 ! proteinase activated receptor binding [Term] id: CCO:F0004883 name: type 2 proteinase activated receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 proteinase activated receptor." [GOC:mah, GOC:nln] synonym: "type 2 proteinase activated receptor ligand" NARROW [] xref: GO:0031873 is_a: CCO:F0004881 ! proteinase activated receptor binding [Term] id: CCO:F0004884 name: type 3 proteinase activated receptor binding namespace: molecular_function def: "Interacting selectively with a type 3 proteinase activated receptor." [GOC:mah, GOC:nln] synonym: "type 3 proteinase activated receptor ligand" NARROW [] xref: GO:0031874 is_a: CCO:F0004881 ! proteinase activated receptor binding [Term] id: CCO:F0004885 name: type 4 proteinase activated receptor binding namespace: molecular_function def: "Interacting selectively with a type 4 proteinase activated receptor." [GOC:mah, GOC:nln] synonym: "type 4 proteinase activated receptor ligand" NARROW [] xref: GO:0031875 is_a: CCO:F0004881 ! proteinase activated receptor binding [Term] id: CCO:F0004886 name: secretin receptor binding namespace: molecular_function def: "Interacting selectively with a secretin receptor." [GOC:mah, GOC:nln] synonym: "secretin receptor ligand" NARROW [] xref: GO:0031876 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004887 name: somatostatin receptor binding namespace: molecular_function def: "Interacting selectively with a somatostatin receptor." [GOC:mah, GOC:nln] synonym: "somatostatin receptor ligand" NARROW [] xref: GO:0031877 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004888 name: type 1 somatostatin receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 somatostatin receptor." [GOC:mah, GOC:nln] synonym: "type 1 somatostatin receptor ligand" NARROW [] xref: GO:0031878 is_a: CCO:F0004887 ! somatostatin receptor binding [Term] id: CCO:F0004889 name: type 2 somatostatin receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 somatostatin receptor." [GOC:mah, GOC:nln] synonym: "type 2 somatostatin receptor ligand" NARROW [] xref: GO:0031879 is_a: CCO:F0004887 ! somatostatin receptor binding [Term] id: CCO:F0004890 name: type 3 somatostatin receptor binding namespace: molecular_function def: "Interacting selectively with a type 3 somatostatin receptor." [GOC:mah, GOC:nln] synonym: "type 3 somatostatin receptor ligand" NARROW [] xref: GO:0031880 is_a: CCO:F0004887 ! somatostatin receptor binding [Term] id: CCO:F0004891 name: type 4 somatostatin receptor binding namespace: molecular_function def: "Interacting selectively with a type 4 somatostatin receptor." [GOC:mah, GOC:nln] synonym: "type 4 somatostatin receptor ligand" NARROW [] xref: GO:0031881 is_a: CCO:F0004887 ! somatostatin receptor binding [Term] id: CCO:F0004892 name: type 5 somatostatin receptor binding namespace: molecular_function def: "Interacting selectively with a type 5 somatostatin receptor." [GOC:mah, GOC:nln] synonym: "type 5 somatostatin receptor ligand" NARROW [] xref: GO:0031882 is_a: CCO:F0004887 ! somatostatin receptor binding [Term] id: CCO:F0004893 name: taste receptor binding namespace: molecular_function def: "Interacting selectively with a taste receptor." [GOC:mah, GOC:nln] synonym: "taste receptor ligand" NARROW [] xref: GO:0031883 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004894 name: type 1 member 1 taste receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 member 1 taste receptor." [GOC:mah, GOC:nln] synonym: "type 1 member 1 taste receptor ligand" NARROW [] xref: GO:0031884 is_a: CCO:F0004893 ! taste receptor binding [Term] id: CCO:F0004895 name: type 1 member 2 taste receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 member 2 taste receptor." [GOC:mah, GOC:nln] synonym: "type 1 member 2 taste receptor ligand" NARROW [] xref: GO:0031885 is_a: CCO:F0004893 ! taste receptor binding [Term] id: CCO:F0004896 name: type 1 member 3 taste receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 member 3 taste receptor." [GOC:mah, GOC:nln] synonym: "sweet taste receptor binding" EXACT [] synonym: "type 1 member 3 taste receptor ligand" NARROW [] xref: GO:0031886 is_a: CCO:F0004893 ! taste receptor binding [Term] id: CCO:F0004897 name: urotensin receptor binding namespace: molecular_function def: "Interacting selectively with a urotensin receptor." [GOC:mah, GOC:nln] synonym: "urotensin receptor ligand" NARROW [] xref: GO:0031889 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004898 name: vasoactive intestinal polypeptide receptor binding namespace: molecular_function def: "Interacting selectively with a vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln] synonym: "vasoactive intestinal polypeptide receptor ligand" NARROW [] synonym: "VIP receptor binding" EXACT [] xref: GO:0031890 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004899 name: type 1 vasoactive intestinal polypeptide receptor binding namespace: molecular_function def: "Interacting selectively with a type 1 vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln] synonym: "type 1 vasoactive intestinal polypeptide receptor ligand" NARROW [] synonym: "type 2 PACAP receptor binding" EXACT [] xref: GO:0031891 is_a: CCO:F0004898 ! vasoactive intestinal polypeptide receptor binding [Term] id: CCO:F0004900 name: type 2 vasoactive intestinal polypeptide receptor binding namespace: molecular_function def: "Interacting selectively with a type 2 vasoactive intestinal polypeptide receptor." [GOC:mah, GOC:nln] synonym: "type 2 vasoactive intestinal polypeptide receptor ligand" NARROW [] synonym: "type 3 PACAP receptor binding" EXACT [] xref: GO:0031892 is_a: CCO:F0004898 ! vasoactive intestinal polypeptide receptor binding [Term] id: CCO:F0004901 name: vasopressin receptor binding namespace: molecular_function def: "Interacting selectively with a vasopressin receptor." [GOC:mah, GOC:nln] synonym: "vasopressin receptor ligand" NARROW [] xref: GO:0031893 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0004902 name: V1A vasopressin receptor binding namespace: molecular_function def: "Interacting selectively with a V1A vasopressin receptor." [GOC:mah, GOC:nln] synonym: "V1A vasopressin receptor ligand" NARROW [] xref: GO:0031894 is_a: CCO:F0004901 ! vasopressin receptor binding [Term] id: CCO:F0004903 name: V1B vasopressin receptor binding namespace: molecular_function def: "Interacting selectively with a V1B vasopressin receptor." [GOC:mah, GOC:nln] synonym: "V1B vasopressin receptor ligand" NARROW [] xref: GO:0031895 is_a: CCO:F0004901 ! vasopressin receptor binding [Term] id: CCO:F0004904 name: V2 vasopressin receptor binding namespace: molecular_function def: "Interacting selectively with a V2 vasopressin receptor." [GOC:mah, GOC:nln] synonym: "V2 vasopressin receptor ligand" NARROW [] xref: GO:0031896 is_a: CCO:F0004901 ! vasopressin receptor binding [Term] id: CCO:F0004905 name: vitamin B6 transporter activity namespace: molecular_function def: "Enables the directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of, within or between cells." [GOC:mah] xref: GO:0031924 is_a: CCO:F0008065 ! vitamin transporter activity [Term] id: CCO:F0004906 name: pyridoxal transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of pyridoxal across a membrane into, out of, within or between cells. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] synonym: "pyridoxal transporter activity" BROAD [] xref: GO:0031925 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0004905 ! vitamin B6 transporter activity [Term] id: CCO:F0004907 name: pyridoxal phosphate transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of pyridoxal phosphate into, out of, within or between cells; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6." [GOC:mah] xref: GO:0031926 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0004905 ! vitamin B6 transporter activity [Term] id: CCO:F0004908 name: pyridoxamine transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of pyridoxamine into, out of, within or between cells. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] xref: GO:0031927 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0004905 ! vitamin B6 transporter activity [Term] id: CCO:F0004909 name: pyridoxine transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of pyridoxine across a membrane into, out of, within or between cells. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate." [GOC:mah] synonym: "pyridoxine transporter activity" BROAD [] xref: GO:0031928 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity is_a: CCO:F0004905 ! vitamin B6 transporter activity [Term] id: CCO:F0004910 name: short-chain-fatty-acid-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a short-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids have chain lengths of less than 8 carbons." [EC:6.2.1.3, GOC:mah] synonym: "short-chain fatty acid activation" RELATED [] synonym: "short-chain fatty acid-CoA ligase activity" EXACT [] xref: GO:0031955 is_a: CCO:F0002996 ! fatty-acid ligase activity [Term] id: CCO:F0004911 name: medium-chain-fatty-acid-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; medium-chain fatty acids have chain lengths of C8-12." [EC:6.2.1.3, GOC:mah] synonym: "medium-chain fatty acid activation" RELATED [] synonym: "medium-chain fatty acid-CoA ligase activity" EXACT [] xref: GO:0031956 is_a: CCO:F0002996 ! fatty-acid ligase activity [Term] id: CCO:F0004912 name: very-long-chain-fatty-acid-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a very-long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; very-long-chain fatty acids have chain lengths of greater than C18." [EC:6.2.1.3, GOC:mah] synonym: "very-long-chain fatty acid activation" RELATED [] synonym: "very-long-chain fatty acid-CoA ligase activity" EXACT [] xref: GO:0031957 is_a: CCO:F0002996 ! fatty-acid ligase activity [Term] id: CCO:F0004913 name: cortisol receptor binding namespace: molecular_function def: "Interacting selectively with a cortisol receptor." [GOC:mah, PMID:12511169] xref: GO:0031961 is_a: CCO:F0005587 ! glucocorticoid receptor binding [Term] id: CCO:F0004914 name: mineralocorticoid receptor binding namespace: molecular_function def: "Interacting selectively with a mineralocorticoid receptor." [GOC:mah, PMID:12511169] xref: GO:0031962 is_a: CCO:F0005586 ! steroid hormone receptor binding [Term] id: CCO:F0004915 name: cortisol receptor activity namespace: molecular_function def: "Combining with cortisol to initiate a change in cell activity." [GOC:mah, PMID:12511169] xref: GO:0031963 is_a: CCO:F0001236 ! glucocorticoid receptor activity [Term] id: CCO:F0004916 name: beta-alanyl-histamine hydrolase activity namespace: molecular_function def: "Catalysis of the conversion of beta-alanyl-histamine to histamine." [GOC:rc, PMID:16299587] synonym: "carcinine hydrolase activity" EXACT [] xref: GO:0031964 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0004917 name: energy transducer activity namespace: molecular_function def: "The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell." [GOC:go_curators] subset: goslim_pir synonym: "light harvesting activity" RELATED [] synonym: "photon capture" RELATED [] xref: GO:0031992 is_a: CCO:F0008240 ! molecular transducer activity [Term] id: CCO:F0004918 name: light transducer activity namespace: molecular_function def: "Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell." [GOC:mah, GOC:mlg] xref: GO:0031993 is_a: CCO:F0004917 ! energy transducer activity [Term] id: CCO:F0004919 name: insulin-like growth factor I binding namespace: molecular_function def: "Interacting selectively with insulin-like growth factor I." [GOC:mah] synonym: "IGF-I binding" EXACT [] xref: GO:0031994 is_a: CCO:F0001651 ! insulin-like growth factor binding [Term] id: CCO:F0004920 name: insulin-like growth factor II binding namespace: molecular_function def: "Interacting selectively with insulin-like growth factor II." [GOC:mah] synonym: "IGF-II binding" EXACT [] xref: GO:0031995 is_a: CCO:F0001651 ! insulin-like growth factor binding [Term] id: CCO:F0004921 name: thioesterase binding namespace: molecular_function def: "Interacting selectively with any thioesterase enzyme." [GOC:dl] synonym: "thiolesterase binding" EXACT [] xref: GO:0031996 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0004922 name: N-terminal myristoylation domain binding namespace: molecular_function def: "Interacting selectively with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin." [GOC:dl, GOC:jsg, PMID:15632291] xref: GO:0031997 is_a: CCO:F0006791 ! protein N-terminus binding [Term] id: CCO:F0004923 name: 1,4-alpha-glucan 6-alpha-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer an alpha-D-glucosyl residue in a 1,4-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a 1,4-alpha-D-glucan." [EC:2.4.1.24] synonym: "1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase activity" EXACT [] synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan(D-glucose) 6-alpha-D-glucosyltransferase activity" EXACT [] synonym: "D-glucosyltransferase" BROAD [] synonym: "oligoglucan-branching glycosyltransferase activity" RELATED [EC:2.4.1.24] synonym: "T-enzyme" NARROW [] xref: EC:2.4.1.24 xref: GO:0032001 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0004924 name: interleukin-28 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-28 receptor." [GOC:rh2] synonym: "IL-28" NARROW [] synonym: "interleukin-28 receptor ligand" NARROW [] xref: GO:0032003 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0004925 name: 2-methylbutanal reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+." [GOC:mah, PMID:12210903] synonym: "2-methylbutyraldehyde reductase activity" EXACT [] xref: GO:0032018 is_a: CCO:F0000510 ! aldehyde reductase activity [Term] id: CCO:F0004926 name: myosin light chain binding namespace: molecular_function def: "Interacting selectively with a light chain of a myosin complex." [GOC:mah] xref: GO:0032027 is_a: CCO:F0003516 ! myosin binding [Term] id: CCO:F0004927 name: myosin head/neck binding namespace: molecular_function def: "Interacting selectively with the head/neck region of a myosin heavy chain." [GOC:mah] xref: GO:0032028 is_a: CCO:F0004935 ! myosin heavy chain binding [Term] id: CCO:F0004928 name: myosin tail binding namespace: molecular_function def: "Interacting selectively with the tail region of a myosin heavy chain." [GOC:mah] xref: GO:0032029 is_a: CCO:F0004935 ! myosin heavy chain binding [Term] id: CCO:F0004929 name: myosin I light chain binding namespace: molecular_function def: "Interacting selectively with a light chain of a myosin I complex." [GOC:mah] xref: GO:0032030 is_a: CCO:F0003517 ! myosin I binding is_a: CCO:F0004926 ! myosin light chain binding [Term] id: CCO:F0004930 name: myosin I head/neck binding namespace: molecular_function def: "Interacting selectively with the head/neck region of a myosin I heavy chain." [GOC:mah] xref: GO:0032031 is_a: CCO:F0004927 ! myosin head/neck binding is_a: CCO:F0004936 ! myosin I heavy chain binding [Term] id: CCO:F0004931 name: myosin I tail binding namespace: molecular_function def: "Interacting selectively with the tail region of a myosin I heavy chain." [GOC:mah] xref: GO:0032032 is_a: CCO:F0004928 ! myosin tail binding is_a: CCO:F0004936 ! myosin I heavy chain binding [Term] id: CCO:F0004932 name: myosin II light chain binding namespace: molecular_function def: "Interacting selectively with a light chain of a myosin II complex." [GOC:mah] xref: GO:0032033 is_a: CCO:F0004926 ! myosin light chain binding is_a: CCO:F0006091 ! myosin II binding [Term] id: CCO:F0004933 name: myosin II head/neck binding namespace: molecular_function def: "Interacting selectively with the head/neck region of a myosin II heavy chain." [GOC:mah] xref: GO:0032034 is_a: CCO:F0004927 ! myosin head/neck binding is_a: CCO:F0004937 ! myosin II heavy chain binding [Term] id: CCO:F0004934 name: myosin II tail binding namespace: molecular_function def: "Interacting selectively with the tail region of a myosin II heavy chain." [GOC:mah] xref: GO:0032035 is_a: CCO:F0004928 ! myosin tail binding is_a: CCO:F0004937 ! myosin II heavy chain binding [Term] id: CCO:F0004935 name: myosin heavy chain binding namespace: molecular_function def: "Interacting selectively with a heavy chain of a myosin complex." [GOC:mah] xref: GO:0032036 is_a: CCO:F0003516 ! myosin binding [Term] id: CCO:F0004936 name: myosin I heavy chain binding namespace: molecular_function def: "Interacting selectively with a heavy chain of a myosin I complex." [GOC:mah] xref: GO:0032037 is_a: CCO:F0003517 ! myosin I binding is_a: CCO:F0004935 ! myosin heavy chain binding [Term] id: CCO:F0004937 name: myosin II heavy chain binding namespace: molecular_function def: "Interacting selectively with a heavy chain of a myosin II complex." [GOC:mah] xref: GO:0032038 is_a: CCO:F0004935 ! myosin heavy chain binding is_a: CCO:F0006091 ! myosin II binding [Term] id: CCO:F0004938 name: NAD-dependent histone deacetylase activity (H3-K14 specific) namespace: molecular_function def: "Catalysis of the NAD-dependent removal of an acetyl group from lysine at position 14 of the histone H3 protein." [GOC:mah] xref: GO:0032041 is_a: CCO:F0003591 ! NAD-dependent histone deacetylase activity is_a: CCO:F0004630 ! histone deacetylase activity (H3-K14 specific) [Term] id: CCO:F0004939 name: clathrin heavy chain binding namespace: molecular_function def: "Interacting selectively with a clathrin heavy chain." [GOC:mah] xref: GO:0032050 is_a: CCO:F0004372 ! clathrin binding [Term] id: CCO:F0004940 name: clathrin light chain binding namespace: molecular_function def: "Interacting selectively with a clathrin light chain." [GOC:mah] xref: GO:0032051 is_a: CCO:F0004372 ! clathrin binding [Term] id: CCO:F0004941 name: bile acid binding namespace: molecular_function def: "Interacting selectively with bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:rph] xref: GO:0032052 is_a: CCO:F0004660 ! carboxylic acid binding [Term] id: CCO:F0004942 name: Type IV site-specific deoxyribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated)." [PMID:12654995] synonym: "Type IV restriction enzyme activity" EXACT [] xref: GO:0032067 is_a: CCO:F0003014 ! restriction endodeoxyribonuclease activity [Term] id: CCO:F0004943 name: NACHT domain binding namespace: molecular_function def: "Interacting selectively with a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, an Mg(2+)-binding site and five more specific motifs." [GOC:rl] xref: GO:0032089 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004944 name: Pyrin domain binding namespace: molecular_function def: "Interacting selectively with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain." [GOC:rl] synonym: "DAPIN domain binding" EXACT [] synonym: "PAAD domain binding" EXACT [] xref: GO:0032090 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004945 name: SAM domain binding namespace: molecular_function def: "Interacting selectively with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes." [GOC:mcc, PMID:16337230] synonym: "Sterile Alpha Motif domain binding" EXACT [] xref: GO:0032093 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004946 name: sorbose reductase activity namespace: molecular_function def: "L-sorbose + NADPH + H+ = D-glucitol + NADP+. The reaction may occur, to a minor extent, in the reverse direction." [EC:1.1.11.289, GOC:mcc] synonym: "D-glucitol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.289] synonym: "Sou1p" RELATED [EC:1.1.1.289] xref: EC:1.1.1.289 xref: GO:0032115 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004947 name: histone deacetylase activity (H3-K9 specific) namespace: molecular_function def: "Catalysis of the removal of an acetyl group from lysine at position 9 of the histone H3 protein." [GOC:mah] xref: GO:0032129 is_a: CCO:F0000816 ! histone deacetylase activity [Term] id: CCO:F0004948 name: alkylated DNA binding namespace: molecular_function def: "Interacting selectively with alkylated residues in DNA." [GOC:mah] xref: GO:0032131 is_a: CCO:F0000279 ! damaged DNA binding [Term] id: CCO:F0004949 name: O6-alkylguanine-DNA binding namespace: molecular_function def: "Interacting selectively with O6-alkylguanine adducts in DNA." [GOC:mah, PMID:16679453] xref: GO:0032132 is_a: CCO:F0004948 ! alkylated DNA binding [Term] id: CCO:F0004950 name: mispaired DNA binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing pyrimidine/purine mispairs." [GOC:vk] synonym: "mispair binding" EXACT [] xref: GO:0032134 is_a: CCO:F0004616 ! mismatched DNA binding [Term] id: CCO:F0004951 name: DNA insertion or deletion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing insertions or deletions." [GOC:vk] synonym: "DNA insertion binding" NARROW [] synonym: "insertion binding" EXACT [] xref: GO:0032135 is_a: CCO:F0004616 ! mismatched DNA binding [Term] id: CCO:F0004952 name: adenine/cytosine mispair binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing an A/C mispair." [GOC:vk] synonym: "A/C mispair binding" EXACT [] xref: GO:0032136 is_a: CCO:F0004950 ! mispaired DNA binding [Term] id: CCO:F0004953 name: guanine/thymine mispair binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing an G/T mispair." [GOC:vk] synonym: "G/T mispair binding" EXACT [] xref: GO:0032137 is_a: CCO:F0004950 ! mispaired DNA binding [Term] id: CCO:F0004954 name: single base insertion or deletion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing a single base insertion or deletion." [GOC:vk] synonym: "single base insertion binding" NARROW [] xref: GO:0032138 is_a: CCO:F0004951 ! DNA insertion or deletion binding [Term] id: CCO:F0004955 name: dinucleotide insertion or deletion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing a dinucleotide insertion or deletion." [GOC:vk] synonym: "dinucleotide insertion binding" NARROW [] xref: GO:0032139 is_a: CCO:F0004951 ! DNA insertion or deletion binding [Term] id: CCO:F0004956 name: single adenine insertion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing a single adenine insertion or a deletion that results in an unpaired adenine." [GOC:mah, GOC:vk] xref: GO:0032140 is_a: CCO:F0004954 ! single base insertion or deletion binding [Term] id: CCO:F0004957 name: single cytosine insertion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing a single cytosine insertion or a deletion that results in an unpaired cytosine." [GOC:mah, GOC:vk] xref: GO:0032141 is_a: CCO:F0004954 ! single base insertion or deletion binding [Term] id: CCO:F0004958 name: single guanine insertion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine." [GOC:mah, GOC:vk] xref: GO:0032142 is_a: CCO:F0004954 ! single base insertion or deletion binding [Term] id: CCO:F0004959 name: single thymine insertion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine." [GOC:mah, GOC:vk] xref: GO:0032143 is_a: CCO:F0004954 ! single base insertion or deletion binding [Term] id: CCO:F0004960 name: succinate-semialdehyde dehydrogenase binding namespace: molecular_function def: "Interacting selectively with succinate-semialdehyde dehydrogenase." [GOC:mah] synonym: "succinic semialdehyde dehydrogenase binding" EXACT [] xref: GO:0032145 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0004961 name: thiosulfate transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in)." [GOC:mlg] xref: GO:0032146 is_a: CCO:F0002595 ! thiosulfate transmembrane transporter activity is_a: CCO:F0005824 ! anion transmembrane-transporting ATPase activity [Term] id: CCO:F0004962 name: dinucleotide repeat insertion binding namespace: molecular_function def: "Interacting selectively with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats." [GOC:mah, GOC:vk] xref: GO:0032181 is_a: CCO:F0004955 ! dinucleotide insertion or deletion binding [Term] id: CCO:F0004963 name: small conjugating protein binding namespace: molecular_function def: "Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein." [GOC:mah] xref: GO:0032182 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004964 name: SUMO binding namespace: molecular_function def: "Interacting selectively with the small ubiquitin-like protein SUMO." [GOC:mah] synonym: "Smt3 binding" RELATED [] synonym: "Smt3 monomer binding" NARROW [] xref: GO:0032183 is_a: CCO:F0004963 ! small conjugating protein binding [Term] id: CCO:F0004965 name: SUMO polymer binding namespace: molecular_function def: "Interacting selectively with a polymer of the small ubiquitin-like protein SUMO." [GOC:mah] synonym: "Smt3 polymer binding" EXACT [] xref: GO:0032184 is_a: CCO:F0004964 ! SUMO binding [Term] id: CCO:F0004966 name: acrosin binding namespace: molecular_function def: "Interacting selectively with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities." [GOC:mah, PMID:12398221] xref: GO:0032190 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0004967 name: acrosin heavy chain binding namespace: molecular_function def: "Interacting selectively with the larger of the two covalently linked polypeptide chains of acrosin." [GOC:mah, PMID:12398221] xref: GO:0032191 is_a: CCO:F0004966 ! acrosin binding [Term] id: CCO:F0004968 name: acrosin light chain binding namespace: molecular_function def: "Interacting selectively with the smaller of the two covalently linked polypeptide chains of acrosin." [GOC:mah, PMID:12398221] xref: GO:0032192 is_a: CCO:F0004966 ! acrosin binding [Term] id: CCO:F0004969 name: glucosaminyl-phosphotidylinositol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glucosaminyl-phosphotidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phosphotidylinositol + CoA." [Reactome:REACT_1049.1] synonym: "GPI-inositol acyltransferase" RELATED [] xref: EC:2.3.1.- xref: GO:0032216 is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0004970 name: riboflavin transporter activity namespace: molecular_function def: "Facilitates the directed movement of riboflavin into, out of, within or between cells. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins." [GOC:rn, PMID:16204239] xref: GO:0032217 is_a: CCO:F0008065 ! vitamin transporter activity [Term] id: CCO:F0004971 name: phosphatidylinositol 3-phosphate binding namespace: molecular_function def: "Interacting selectively with phosphatidylinositol 3-phosphate, a phosphorylated derivative of phosphatidylinositol." [PMID:11557775] synonym: "PtdIns-3-P binding" EXACT [] xref: GO:0032266 is_a: CCO:F0005562 ! phosphoinositide binding [Term] id: CCO:F0004972 name: tRNA(Ile)-lysidine synthase namespace: molecular_function def: "Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine." [PMID:14527414] synonym: "tRNA(Ile)-2-lysyl-cytidine synthase activity" EXACT [] synonym: "tRNA(Ile)-lysidine synthetase activity" EXACT [] xref: EC:6.3.4.- xref: GO:0032267 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0004973 name: double-stranded RNA-specific ribonuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules." [GOC:mah] synonym: "double-stranded RNA-specific RNase activity" EXACT [] synonym: "dsRNA-specific ribonuclease activity" EXACT [] synonym: "dsRNA-specific RNase activity" EXACT [] xref: GO:0032296 is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0004974 name: oxidized DNA binding namespace: molecular_function def: "Interacting selectively with oxidized residues in DNA." [GOC:vk] synonym: "oxidised DNA binding" EXACT [] xref: GO:0032356 is_a: CCO:F0000279 ! damaged DNA binding [Term] id: CCO:F0004975 name: oxidized purine DNA binding namespace: molecular_function def: "Interacting selectively with oxidized purine residues in DNA." [GOC:vk] synonym: "oxidised purine DNA binding" EXACT [] xref: GO:0032357 is_a: CCO:F0004974 ! oxidized DNA binding [Term] id: CCO:F0004976 name: oxidized pyrimidine DNA binding namespace: molecular_function def: "Interacting selectively with oxidized pyrimidine residues in DNA." [GOC:vk] synonym: "oxidised pyrimidine DNA binding" EXACT [] xref: GO:0032358 is_a: CCO:F0004974 ! oxidized DNA binding [Term] id: CCO:F0004977 name: MHC class I receptor activity namespace: molecular_function def: "Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that this term is intended for annotation of gene products that act as receptors for MHC class I protein complexes, not for components of the MHC class I protein complexes themselves. synonym: "alpha-beta T cell receptor activity" RELATED [] synonym: "gamma-delta T cell receptor activity" RELATED [] synonym: "T cell receptor activity" RELATED [] xref: GO:0032393 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0004978 name: MHC class Ib receptor activity namespace: molecular_function def: "Combining with an MHC class Ib protein complex to initiate a change in cellular activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that this term is intended for annotation of gene products that act as receptors for MHC class Ib protein complexes, not for components of the MHC class Ib protein complexes themselves. synonym: "alpha-beta T cell receptor activity" RELATED [] synonym: "gamma-delta T cell receptor activity" RELATED [] synonym: "T cell receptor activity" RELATED [] xref: GO:0032394 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0004979 name: MHC class II receptor activity namespace: molecular_function def: "Combining with an MHC class II protein complex to initiate a change in cellular activity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that this term is intended for annotation of gene products that act as receptors for MHC class II protein complexes, not for components of the MHC class II protein complexes themselves. synonym: "alpha-beta T cell receptor activity" RELATED [] synonym: "gamma-delta T cell receptor activity" RELATED [] synonym: "T cell receptor activity" RELATED [] xref: GO:0032395 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0004980 name: inhibitory MHC class I receptor activity namespace: molecular_function def: "Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte." [GOC:add, PMID:11858820, PMID:9368779, PMID:9597134] xref: GO:0032396 is_a: CCO:F0004977 ! MHC class I receptor activity [Term] id: CCO:F0004981 name: activating MHC class I receptor activity namespace: molecular_function def: "Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte." [GOC:add, PMID:11858820, PMID:9597134] xref: GO:0032397 is_a: CCO:F0004977 ! MHC class I receptor activity [Term] id: CCO:F0004982 name: HECT domain binding namespace: molecular_function def: "Interacting selectively with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein." [GOC:mah, Pfam:PF00632] xref: GO:0032399 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004983 name: protein complex binding namespace: molecular_function def: "Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:mah] xref: GO:0032403 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0004984 name: mismatch repair complex binding namespace: molecular_function def: "Interacting selectively with a mismatch repair complex." [GOC:vk] xref: GO:0032404 is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0004985 name: MutLalpha complex binding namespace: molecular_function def: "Interacting selectively with the mismatch repair complex MutLalpha." [GOC:vk] xref: GO:0032405 is_a: CCO:F0004984 ! mismatch repair complex binding [Term] id: CCO:F0004986 name: MutLbeta complex binding namespace: molecular_function def: "Interacting selectively with the mismatch repair complex MutLbeta." [GOC:vk] xref: GO:0032406 is_a: CCO:F0004984 ! mismatch repair complex binding [Term] id: CCO:F0004987 name: MutSalpha complex binding namespace: molecular_function def: "Interacting selectively with the mismatch repair complex MutSalpha." [GOC:vk] xref: GO:0032407 is_a: CCO:F0004984 ! mismatch repair complex binding [Term] id: CCO:F0004988 name: MutSbeta complex binding namespace: molecular_function def: "Interacting selectively with the mismatch repair complex MutSbeta." [GOC:vk] xref: GO:0032408 is_a: CCO:F0004984 ! mismatch repair complex binding [Term] id: CCO:F0004989 name: purine-rich negative regulatory element binding namespace: molecular_function def: "Interacting selectively with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes." [GOC:mah, PMID:9819411] synonym: "PNR element binding" BROAD [] xref: GO:0032422 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0004990 name: GBD domain binding namespace: molecular_function def: "Interacting selectively with the GBD (GTPase protein binding domain) domain of small GTPases." [GOC:pg] synonym: "CRIB motif binding" EXACT [] xref: GO:0032427 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0004991 name: beta-N-acetylgalactosaminidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides." [EC:3.2.1.53] synonym: "beta-acetylgalactosaminidase activity" EXACT [EC:3.2.1.53] synonym: "beta-D-N-acetylgalactosaminidase activity" EXACT [EC:3.2.1.53] synonym: "beta-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity" EXACT [EC:3.2.1.53] synonym: "N-acetyl-beta-D-galactosaminidase activity" EXACT [EC:3.2.1.53] synonym: "N-acetyl-beta-galactosaminidase activity" EXACT [EC:3.2.1.53] synonym: "N-acetylgalactosaminidase activity" EXACT [EC:3.2.1.53] xref: EC:3.2.1.53 xref: GO:0032428 is_a: CCO:F0000947 ! beta-N-acetylhexosaminidase activity [Term] id: CCO:F0004992 name: 2-alkenal reductase activity namespace: molecular_function def: "Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+." [EC:1.3.1.74, PMID:16299173] synonym: "n-alkanal:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.3.1.74] synonym: "NAD(P)H-dependent alkenal/one oxidoreductase activity" EXACT [EC:1.3.1.74] synonym: "NADPH:2-alkenal alpha,beta-hydrogenase activity" EXACT [] xref: EC:1.3.1.74 xref: GO:0032440 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004993 name: pheophorbide a oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite (RCC) + oxidized ferredoxin + H2O." [PMID:14657372, PMID:16448336] xref: EC:1.8.-.- xref: GO:0032441 is_a: CCO:F0003311 ! oxidoreductase activity, acting on iron-sulfur proteins as donors [Term] id: CCO:F0004994 name: phenylcoumaran benzylic ether reductase activity namespace: molecular_function def: "Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction dehydrodiconiferyl alcohol + NADPH = isodihydrodehydrodiconiferyl alcohol + NADP." [PMID:11030549, PMID:13129921] synonym: "PCBER activity" EXACT [] xref: EC:1.1.1.- xref: GO:0032442 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0004995 name: DNA hairpin binding namespace: molecular_function def: "Interacting selectively with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences." [GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0032448 is_a: CCO:F0000040 ! DNA secondary structure binding [Term] id: CCO:F0004996 name: maltase activity namespace: molecular_function def: "Catalysis of the hydrolysis of maltose by an alpha-D-glucosidase-type action." [GOC:pd] xref: GO:0032450 is_a: CCO:F0000943 ! alpha-glucosidase activity [Term] id: CCO:F0004997 name: demethylase activity namespace: molecular_function def: "Catalysis of the removal of a methyl group from a substrate." [GOC:mah] subset: goslim_pir xref: GO:0032451 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0004998 name: histone demethylase activity namespace: molecular_function def: "Catalysis of the removal of a methyl group from a histone." [GOC:mah] xref: GO:0032452 is_a: CCO:F0004997 ! demethylase activity [Term] id: CCO:F0004999 name: histone demethylase activity (H3-K4 specific) namespace: molecular_function def: "Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein." [GOC:mah] xref: GO:0032453 is_a: CCO:F0004998 ! histone demethylase activity [Term] id: CCO:F0005000 name: histone demethylase activity (H3-K9 specific) namespace: molecular_function def: "Catalysis of the removal of a methyl group from lysine at position 9 of the histone H3 protein." [GOC:mah] xref: GO:0032454 is_a: CCO:F0004998 ! histone demethylase activity [Term] id: CCO:F0005001 name: muramyl dipeptide binding namespace: molecular_function def: "Interacting selectively, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan." [GOC:rl] xref: GO:0032500 is_a: CCO:F0005721 ! peptidoglycan binding [Term] id: CCO:F0005002 name: amino acid-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(in) = ADP + phosphate + amino acid(out)." [GOC:mah] xref: GO:0032518 is_a: CCO:F0002843 ! amino acid-transporting ATPase activity [Term] id: CCO:F0005003 name: cysteine-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(in) = ADP + phosphate + cysteine(out)." [GOC:mah] synonym: "cysteine exporter" RELATED [] xref: GO:0032519 is_a: CCO:F0005002 ! amino acid-exporting ATPase activity is_a: CCO:F0005091 ! cysteine-transporting ATPase activity [Term] id: CCO:F0005004 name: amino acid-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out) = ADP + phosphate + amino acid(in)." [GOC:mah] xref: GO:0032520 is_a: CCO:F0002843 ! amino acid-transporting ATPase activity [Term] id: CCO:F0005005 name: D-methionine-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(in) = ADP + phosphate + D-methionine(out)." [GOC:mah] synonym: "D-methionine exporter" RELATED [] xref: GO:0032521 is_a: CCO:F0005002 ! amino acid-exporting ATPase activity is_a: CCO:F0005092 ! D-methionine-transporting ATPase activity [Term] id: CCO:F0005006 name: D-methionine-importing ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out) = ADP + phosphate + D-methionine(in)." [GOC:mah] synonym: "D-methionine importer" RELATED [] xref: GO:0032522 is_a: CCO:F0005004 ! amino acid-importing ATPase activity is_a: CCO:F0005092 ! D-methionine-transporting ATPase activity [Term] id: CCO:F0005007 name: silicon efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of silicon from the inside of the cell to the outside of the cell across a membrane." [GOC:mah, PMID:17625566] synonym: "silicon efflux transporter activity" EXACT [] xref: GO:0032523 is_a: CCO:F0001577 ! sugar:hydrogen symporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity is_a: CCO:F0005736 ! arabinose transmembrane transporter activity [Term] id: CCO:F0005008 name: sulfiredoxin activity namespace: molecular_function def: "Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH <=> peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R." [EC:1.8.98.2] synonym: "peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity" EXACT [] synonym: "peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]" RELATED [EC:1.8.98.2] synonym: "Srx1" RELATED [EC:1.8.98.2] synonym: "sulphiredoxin activity" EXACT [] xref: EC:1.8.98.2 xref: GO:0032542 xref: MetaCyc:1.8.98.2-RXN is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0005009 name: deoxyribonucleoside binding namespace: molecular_function def: "Interacting selectively with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose." [GOC:mah] subset: gosubset_prok xref: GO:0032546 is_a: CCO:F0000246 ! nucleoside binding [Term] id: CCO:F0005010 name: purine deoxyribonucleoside binding namespace: molecular_function def: "Interacting selectively with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose." [GOC:mah] subset: gosubset_prok xref: GO:0032547 is_a: CCO:F0000247 ! purine nucleoside binding is_a: CCO:F0005009 ! deoxyribonucleoside binding [Term] id: CCO:F0005011 name: pyrimidine deoxyribonucleoside binding namespace: molecular_function def: "Interacting selectively with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose." [GOC:mah] subset: gosubset_prok xref: GO:0032548 is_a: CCO:F0000248 ! pyrimidine nucleoside binding is_a: CCO:F0005009 ! deoxyribonucleoside binding [Term] id: CCO:F0005012 name: ribonucleoside binding namespace: molecular_function def: "Interacting selectively with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose." [GOC:mah] subset: gosubset_prok xref: GO:0032549 is_a: CCO:F0000246 ! nucleoside binding [Term] id: CCO:F0005013 name: purine ribonucleoside binding namespace: molecular_function def: "Interacting selectively with a purine ribonucleoside, a compound consisting of a purine base linked to ribose." [GOC:mah] subset: gosubset_prok xref: GO:0032550 is_a: CCO:F0000247 ! purine nucleoside binding is_a: CCO:F0005012 ! ribonucleoside binding [Term] id: CCO:F0005014 name: pyrimidine ribonucleoside binding namespace: molecular_function def: "Interacting selectively with a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose." [GOC:mah] subset: gosubset_prok xref: GO:0032551 is_a: CCO:F0000248 ! pyrimidine nucleoside binding is_a: CCO:F0005012 ! ribonucleoside binding [Term] id: CCO:F0005015 name: deoxyribonucleotide binding namespace: molecular_function def: "Interacting selectively with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032552 is_a: CCO:F0000031 ! nucleotide binding [Term] id: CCO:F0005016 name: ribonucleotide binding namespace: molecular_function def: "Interacting selectively with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032553 is_a: CCO:F0000031 ! nucleotide binding [Term] id: CCO:F0005017 name: purine deoxyribonucleotide binding namespace: molecular_function def: "Interacting selectively with a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032554 is_a: CCO:F0003548 ! purine nucleotide binding is_a: CCO:F0005015 ! deoxyribonucleotide binding [Term] id: CCO:F0005018 name: purine ribonucleotide binding namespace: molecular_function def: "Interacting selectively with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032555 is_a: CCO:F0003548 ! purine nucleotide binding is_a: CCO:F0005016 ! ribonucleotide binding [Term] id: CCO:F0005019 name: pyrimidine deoxyribonucleotide binding namespace: molecular_function def: "Interacting selectively with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032556 is_a: CCO:F0004050 ! pyrimidine nucleotide binding is_a: CCO:F0005015 ! deoxyribonucleotide binding [Term] id: CCO:F0005020 name: pyrimidine ribonucleotide binding namespace: molecular_function def: "Interacting selectively with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032557 is_a: CCO:F0004050 ! pyrimidine nucleotide binding is_a: CCO:F0005016 ! ribonucleotide binding [Term] id: CCO:F0005021 name: adenyl deoxyribonucleotide binding namespace: molecular_function def: "Interacting selectively with an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032558 is_a: CCO:F0004466 ! adenyl nucleotide binding is_a: CCO:F0005017 ! purine deoxyribonucleotide binding [Term] id: CCO:F0005022 name: adenyl ribonucleotide binding namespace: molecular_function def: "Interacting selectively with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032559 is_a: CCO:F0004466 ! adenyl nucleotide binding is_a: CCO:F0005018 ! purine ribonucleotide binding [Term] id: CCO:F0005023 name: guanyl deoxyribonucleotide binding namespace: molecular_function def: "Interacting selectively with a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032560 is_a: CCO:F0004044 ! guanyl nucleotide binding is_a: CCO:F0005017 ! purine deoxyribonucleotide binding [Term] id: CCO:F0005024 name: guanyl ribonucleotide binding namespace: molecular_function def: "Interacting selectively with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety." [GOC:mah] subset: gosubset_prok xref: GO:0032561 is_a: CCO:F0004044 ! guanyl nucleotide binding is_a: CCO:F0005018 ! purine ribonucleotide binding [Term] id: CCO:F0005025 name: dAMP binding namespace: molecular_function def: "Interacting selectively with dAMP, deoxyadenosine monophosphate." [GOC:mah] xref: GO:0032562 is_a: CCO:F0005021 ! adenyl deoxyribonucleotide binding [Term] id: CCO:F0005026 name: dADP binding namespace: molecular_function def: "Interacting selectively with dADP, deoxyadenosine diphosphate." [GOC:mah] xref: GO:0032563 is_a: CCO:F0005021 ! adenyl deoxyribonucleotide binding [Term] id: CCO:F0005027 name: dATP binding namespace: molecular_function def: "Interacting selectively with dATP, deoxyadenosine triphosphate." [GOC:mah] xref: GO:0032564 is_a: CCO:F0005021 ! adenyl deoxyribonucleotide binding [Term] id: CCO:F0005028 name: dGMP binding namespace: molecular_function def: "Interacting selectively with dGMP, deoxyguanosine monophosphate." [GOC:mah] xref: GO:0032565 is_a: CCO:F0005023 ! guanyl deoxyribonucleotide binding [Term] id: CCO:F0005029 name: dGDP binding namespace: molecular_function def: "Interacting selectively with dGDP, deoxyguanosine diphosphate." [GOC:mah] xref: GO:0032566 is_a: CCO:F0005023 ! guanyl deoxyribonucleotide binding [Term] id: CCO:F0005030 name: dGTP binding namespace: molecular_function def: "Interacting selectively with dGTP, deoxyguanosine triphosphate." [GOC:mah] xref: GO:0032567 is_a: CCO:F0005023 ! guanyl deoxyribonucleotide binding [Term] id: CCO:F0005031 name: 5'-3' RNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of an RNA helix in the direction 5' to 3'." [GOC:jp] synonym: "5' to 3' RNA helicase activity" EXACT [] xref: GO:0032574 is_a: CCO:F0000309 ! RNA helicase activity [Term] id: CCO:F0005032 name: ATP-dependent 5'-3' RNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of an RNA helix in the direction 5' to 3'." [GOC:jp] synonym: "ATP-dependent 5' to 3' RNA helicase activity" EXACT [] xref: GO:0032575 is_a: CCO:F0000488 ! ATP-dependent RNA helicase activity is_a: CCO:F0005031 ! 5'-3' RNA helicase activity [Term] id: CCO:F0005033 name: O-linoleoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule." [GOC:cb] xref: GO:0032576 is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0005034 name: phosphatidylcholine:cardiolipin O-linoleoyltransferase namespace: molecular_function def: "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule." [GOC:cb, GOC:mah] synonym: "phosphatidylcholine:cardiolipin linoleoyltransferase" EXACT [] xref: GO:0032577 is_a: CCO:F0005033 ! O-linoleoyltransferase activity [Term] id: CCO:F0005035 name: copper-dependent protein binding namespace: molecular_function def: "Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper." [GOC:ecd, PMID:16884690] xref: GO:0032767 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005036 name: cobalt-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in)." [GOC:mlg, GOC:mtg_transport, ISBN:0815340729] synonym: "cobalt ABC transporter" RELATED [] synonym: "cobalt porter activity" RELATED [] synonym: "cobalt transporting ATPase activity" EXACT [] xref: GO:0015632 xref: GO:0032778 is_a: CCO:F0002567 ! cobalt ion transmembrane transporter activity is_a: CCO:F0004186 ! cation-transporting ATPase activity [Term] id: CCO:F0005037 name: lead ion binding namespace: molecular_function def: "Interacting selectively with lead (Pb) ions." [GOC:mah] subset: goslim_generic subset: gosubset_prok xref: GO:0032791 is_a: CCO:F0005808 ! cation binding is_a: CCO:F0006257 ! metal ion binding [Term] id: CCO:F0005038 name: GTPase activating protein binding namespace: molecular_function def: "Interacting selectively with a GTPase activating protein." [GOC:nln] synonym: "GAP binding" EXACT [] xref: GO:0032794 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005039 name: heterotrimeric G-protein binding namespace: molecular_function def: "Interacting selectively with a eterotrimeric G-protein." [GOC:nln] xref: GO:0032795 is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0005040 name: sterol response element binding namespace: molecular_function def: "Interacting selectively with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism." [GOC:vk, PMID:11994399] synonym: "SRE binding" EXACT [] xref: GO:0032810 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0005041 name: tumor necrosis factor receptor superfamily binding namespace: molecular_function def: "Interacting selectively with any member of the tumor necrosis factor receptor superfamily." [GOC:add] synonym: "TNF receptor superfamily binding" EXACT [] xref: GO:0032813 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0005042 name: intramolecular proline-rich ligand binding namespace: molecular_function def: "Interacting selectively with a proline-rich region within the same polypeptide." [GOC:pf] xref: GO:0032840 is_a: CCO:F0005879 ! protein self-association [Term] id: CCO:F0005043 name: calcitonin binding namespace: molecular_function def: "Interacting selectively with calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid." [GOC:ecd] xref: GO:0032841 is_a: CCO:F0003529 ! peptide hormone binding [Term] id: CCO:F0005044 name: hydroperoxide reductase namespace: molecular_function def: "Catalysis of the reaction:2RSH + ROOH = RSSR + ROH + H2O, i.e. the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol plus water." [GOC:mlg, PMID:12540833] xref: GO:0032843 is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0005045 name: xylose reductase activity namespace: molecular_function def: "Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+." [PMID:12724380, PMID:15184173] xref: GO:0032866 is_a: CCO:F0000510 ! aldehyde reductase activity [Term] id: CCO:F0005046 name: arabinose reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+." [PMID:12724380, PMID:15184173] xref: GO:0032867 is_a: CCO:F0000510 ! aldehyde reductase activity [Term] id: CCO:F0005047 name: palmitoyl-CoA 9-desaturase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O." [GOC:kva] synonym: "palmitoyl-CoA delta9-desaturase acitivity" EXACT [] xref: GO:0032896 is_a: CCO:F0003074 ! CoA desaturase activity [Term] id: CCO:F0005048 name: histone lysine N-acetyltransferase activity (H3-K56 specific) namespace: molecular_function def: "Catalysis of the addition of an acetyl group onto lysine at position 56 of the histone H3 protein." [GOC:mah] xref: GO:0032931 is_a: CCO:F0000815 ! H3/H4 histone acetyltransferase activity [Term] id: CCO:F0005049 name: sterol binding namespace: molecular_function def: "Interacting selectively with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol." [ChEBI:15889, GOC:mah] subset: gosubset_prok xref: GO:0032934 is_a: CCO:F0001634 ! steroid binding [Term] id: CCO:F0005050 name: sterol sensor activity namespace: molecular_function def: "Interacting selectively with and responding, e.g. by conformational change, to changes in the cellular level of, a sterol." [GOC:mah] synonym: "sterol-sensing domain" NARROW [] xref: GO:0032935 is_a: CCO:F0005049 ! sterol binding [Term] id: CCO:F0005051 name: inositol tetrakisphosphate 2-kinase activity namespace: molecular_function def: "Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP." [GOC:hf] synonym: "1D-myo-inositol-tetrakisphosphate 2-kinase activity" EXACT [] synonym: "inositol 1,3,4,6-tetrakisphosphate 2-kinase activity" EXACT [] synonym: "inositol-tetrakisphosphate 2-kinase activity" EXACT [] xref: EC:2.7.1.- xref: GO:0032942 is_a: CCO:F0008190 ! inositol tetrakisphosphate kinase activity [Term] id: CCO:F0005052 name: protein complex scaffold namespace: molecular_function def: "Functions to provide a physical suport for the assembly of a multiprotein complex." [GOC:mah] xref: GO:0032947 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005053 name: membrane insertase activity namespace: molecular_function def: "Mediates the integration of proteins into a membrane from the inner side of the membrane. Membrane insertases are highly conserved and include the bacterial YidC family, the plant chloroplast Alb3 family, and the fungal and animal mitochondrial Oxa1/Cox18 family." [PMID:14739936] subset: gosubset_prok xref: GO:0032977 is_a: CCO:F0001997 ! protein transporter activity [Term] id: CCO:F0005054 name: 5-hydroxyvalerate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH." [GOC:mlg, PMID:12406764] xref: GO:0033019 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005055 name: bitter taste receptor activity namespace: molecular_function def: "Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste." [GOC:mah] xref: GO:0033038 is_a: CCO:F0001979 ! taste receptor activity [Term] id: CCO:F0005056 name: salty taste receptor activity namespace: molecular_function def: "Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste." [GOC:mah] xref: GO:0033039 is_a: CCO:F0001979 ! taste receptor activity [Term] id: CCO:F0005057 name: sour taste receptor activity namespace: molecular_function def: "Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste." [GOC:mah] xref: GO:0033040 is_a: CCO:F0001979 ! taste receptor activity [Term] id: CCO:F0005058 name: sweet taste receptor activity namespace: molecular_function def: "Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste." [GOC:mah] xref: GO:0033041 is_a: CCO:F0001979 ! taste receptor activity [Term] id: CCO:F0005059 name: umami taste receptor activity namespace: molecular_function def: "Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates." [GOC:mah] xref: GO:0033042 is_a: CCO:F0001979 ! taste receptor activity [Term] id: CCO:F0005060 name: putrescine aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O." [EC:2.6.1.82, GOC:mlg] synonym: "butane-1,4-diamine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.82] synonym: "PAT activity" EXACT [] synonym: "putrescine transaminase activity" EXACT [] synonym: "putrescine-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.82] synonym: "putrescine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.82] synonym: "putrescine:alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.82] synonym: "YgjG" RELATED [EC:2.6.1.82] xref: EC:2.6.1.82 xref: GO:0033094 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005061 name: acetylcholine receptor binding namespace: molecular_function def: "Interacting selectively with an acetylcholine receptor." [GOC:mah] xref: GO:0033130 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005062 name: ubiquitin activating enzyme binding namespace: molecular_function def: "Interacting selectively with a ubiquitin activating enzyme, any of the E1 proteins." [GOC:mah] xref: GO:0033134 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0005063 name: progesterone receptor binding namespace: molecular_function def: "Interacting selectively with a progesterone receptor." [GOC:mah] xref: GO:0033142 is_a: CCO:F0005586 ! steroid hormone receptor binding [Term] id: CCO:F0005064 name: FFAT motif binding namespace: molecular_function def: "Interacting selectively with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family." [PMID:12727870, PMID:15455074, PMID:16004875] xref: GO:0033149 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0005065 name: oligogalacturonide transporting ATPase namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in)." [GOC:mlg] xref: GO:0033154 is_a: CCO:F0002841 ! oligosaccharide-transporting ATPase activity is_a: CCO:F0002877 ! oligosaccharide transporting porin activity [Term] id: CCO:F0005066 name: oligogalacturonide transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of oligogalacturonide from one side of the membrane to the other." [GOC:mlg] xref: GO:0033155 is_a: CCO:F0002634 ! oligosaccharide transmembrane transporter activity [Term] id: CCO:F0005067 name: mitogen-activated protein kinase kinase kinase kinase binding namespace: molecular_function def: "Interacting selectively with a mitogen-activated protein kinase kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase kinase." [GOC:mah] synonym: "MAPKKKK binding" EXACT [] xref: GO:0033161 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0005068 name: glycolipid 6-alpha-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,6-D-mannosyl-D-mannose linkage." [EC:2.4.1.232, GOC:mcc, PMID:16878994] synonym: "GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.232] synonym: "GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.232] synonym: "initiation-specific alpha-1,6-mannosyltransferase activity" EXACT [EC:2.4.1.232] xref: EC:2.4.1.231 xref: GO:0033164 is_a: CCO:F0000003 ! alpha-1,6-mannosyltransferase activity is_a: CCO:F0000794 ! glycolipid mannosyltransferase activity [Term] id: CCO:F0005069 name: DNA-protein loading ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of a protein or protein complex onto a DNA molecule." [GOC:mah, GOC:vw] xref: GO:0033170 is_a: CCO:F0001707 ! DNA-dependent ATPase activity [Term] id: CCO:F0005070 name: inositol hexakisphosphate 4-kinase or 6-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate or ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate." [PMID:17412958, PMID:17412959] xref: GO:0033187 is_a: CCO:F0000111 ! inositol hexakisphosphate kinase activity [Term] id: CCO:F0005071 name: sphingomyelin synthase activity namespace: molecular_function def: "Catalysis of the reaction: a ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol." [EC:2.7.8.27] synonym: "ceramide:phosphatidylcholine cholinephosphotransferase activity" EXACT [EC:2.7.8.27] synonym: "phosphatidylcholine:ceramide cholinephosphotransferase activity" EXACT [EC:2.7.8.27] synonym: "SM synthase activity" EXACT [EC:2.7.8.27] synonym: "SMS1" RELATED [EC:2.7.8.27] synonym: "SMS2" RELATED [EC:2.7.8.27] xref: EC:2.7.8.27 xref: GO:0033188 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0005072 name: solanapyrone synthase activity namespace: molecular_function def: "Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A." [GOC:cb, PMID:9659400] xref: GO:0033190 is_a: CCO:F0002427 ! cyclase activity [Term] id: CCO:F0005073 name: macrophomate synthase activity namespace: molecular_function def: "Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate." [ChEBI:38228, GOC:cb, PMID:10984474] xref: GO:0033191 is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0005074 name: calmodulin-dependent protein phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin." [GOC:mah, PMID:15359118] synonym: "Ca2+/CaM-dependent protein phosphatase activity" RELATED [] synonym: "calcineurin activity" NARROW [] synonym: "calcium- and calmodulin-dependent protein phosphatase activity" EXACT [] synonym: "calcium/calmodulin-dependent protein phosphatase activity" EXACT [] xref: GO:0033192 is_a: CCO:F0001088 ! calcium-dependent protein serine/threonine phosphatase activity [Term] id: CCO:F0005075 name: tryparedoxin peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: tryparedoxin + H2O2 = tryparedoxin disulfide + H2O." [GOC:mah] synonym: "TXNPx activity" EXACT [] xref: GO:0033196 is_a: CCO:F0008212 ! peroxiredoxin activity [Term] id: CCO:F0005076 name: inositol heptakisphosphate 4-kinase or 6-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, or ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate." [PMID:17412958] xref: GO:0033199 is_a: CCO:F0000112 ! inositol heptakisphosphate kinase activity [Term] id: CCO:F0005077 name: inositol heptakisphosphate 5-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, or ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate." [PMID:17412958] synonym: "diphosphoinositol-pentakisphosphate 5-kinase activity" EXACT [] synonym: "IP7 5-kinase activity" EXACT [] xref: GO:0033200 is_a: CCO:F0000112 ! inositol heptakisphosphate kinase activity [Term] id: CCO:F0005078 name: alpha-1,4-glucan synthase activity namespace: molecular_function def: "Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP." [PMID:17472966] synonym: "1,4-alpha-glucan synthase activity" EXACT [] xref: GO:0033201 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0005079 name: ribonuclease P RNA binding namespace: molecular_function def: "Interacting selectively with the RNA subunit of ribonuclease P." [GOC:pg, PMID:11455963] synonym: "RNase P RNA binidng" EXACT [] xref: GO:0033204 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0005080 name: beta-1,4-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage." [GOC:mah] synonym: "beta-1,4-GalNAc transferase activity" EXACT [] xref: GO:0033207 is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0005081 name: UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide." [GOC:mah, PMID:12678917, PMID:16024623] synonym: "Sda beta 1,4GalNAc transferase" RELATED [] synonym: "UDP-GalNAc:Neu5Ac-alpha-2-Gal-beta-1-R beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [] xref: GO:0033208 is_a: CCO:F0005080 ! beta-1,4-N-acetylgalactosaminyltransferase activity [Term] id: CCO:F0005082 name: amide binding namespace: molecular_function def: "Interacting selectively with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [ChEBI:32988, GOC:mah] subset: goslim_pir xref: GO:0033218 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005083 name: urea binding namespace: molecular_function def: "Interacting selectively with urea, a water-soluble carboxamide with the structure H2N-CO-NH2." [ChEBI:16199, GOC:mah, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0033219 is_a: CCO:F0005082 ! amide binding [Term] id: CCO:F0005084 name: amide-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in)." [GOC:mah] subset: gosubset_prok xref: GO:0033220 is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances is_a: CCO:F0005729 ! amide transporter activity [Term] id: CCO:F0005085 name: urea-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in)." [GOC:mlg] subset: gosubset_prok synonym: "carbamide-transporting ATPase activity" EXACT [] xref: GO:0033221 is_a: CCO:F0002676 ! urea transmembrane transporter activity is_a: CCO:F0005084 ! amide-transporting ATPase activity [Term] id: CCO:F0005086 name: xylose binding namespace: molecular_function def: "Interacting selectively with the D- or L-enantiomer of xylose." [GOC:mah] subset: gosubset_prok xref: GO:0033222 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0005087 name: 2-aminoethylphosphonate transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of 2-aminoethylphosphonate into, out of, within or between cells." [GOC:mlg] synonym: "2-phosphonoethylamine transmembrane transporter activity" EXACT [] synonym: "ciliatine transporter activity" EXACT [] xref: GO:0033224 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0005088 name: 2-aminoethylphosphonate transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in)." [GOC:mlg] synonym: "2-phosphonoethylamine transporting ATPase activity" EXACT [] synonym: "ciliatine transportingATPase activity" EXACT [] xref: GO:0033225 is_a: CCO:F0004647 ! amine-transporting ATPase activity is_a: CCO:F0005087 ! 2-aminoethylphosphonate transmembrane transporter activity [Term] id: CCO:F0005089 name: 2-aminoethylphosphonate binding namespace: molecular_function def: "Interacting selectively with 2-aminoethylphosphonate." [GOC:mlg] synonym: "2-phosphonoethylamine binding" EXACT [] synonym: "ciliatine binding" EXACT [] xref: GO:0033226 is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0005090 name: cysteine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of cysteine from one side of the membrane to the other." [GOC:mah] xref: GO:0033229 is_a: CCO:F0000019 ! sulfur amino acid transmembrane transporter activity [Term] id: CCO:F0005091 name: cysteine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out)." [GOC:mlg] xref: GO:0033230 is_a: CCO:F0002843 ! amino acid-transporting ATPase activity is_a: CCO:F0005090 ! cysteine transmembrane transporter activity [Term] id: CCO:F0005092 name: D-methionine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out)." [GOC:mlg] xref: GO:0033232 is_a: CCO:F0002843 ! amino acid-transporting ATPase activity is_a: CCO:F0007340 ! D-methionine transmembrane transporter activity [Term] id: CCO:F0005093 name: penicillinase activity namespace: molecular_function def: "Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin." [GOC:mlg] xref: GO:0033250 is_a: CCO:F0002144 ! beta-lactamase activity [Term] id: CCO:F0005094 name: cephalosporinase activity namespace: molecular_function def: "Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin." [GOC:mlg] xref: GO:0033251 is_a: CCO:F0002144 ! beta-lactamase activity [Term] id: CCO:F0005095 name: bontoxilysin activity namespace: molecular_function def: "Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates." [EC:3.4.24.69] subset: gosubset_prok synonym: "BoNT" RELATED [EC:3.4.24.69] synonym: "botulinum neurotoxin activity" EXACT [] xref: EC:3.4.24.69 xref: GO:0033264 xref: MetaCyc:3.4.24.69-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0005096 name: choline binding namespace: molecular_function def: "Interacting selectively with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium." [ChEBI:15354, GOC:mlg] xref: GO:0033265 is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0005097 name: choline-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of choline across a membrane." [GOC:mlg] xref: GO:0033266 is_a: CCO:F0002691 ! choline transmembrane transporter activity is_a: CCO:F0004647 ! amine-transporting ATPase activity [Term] id: CCO:F0005098 name: organic acid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out)." [GOC:mlg] xref: GO:0033283 is_a: CCO:F0001570 ! organic acid transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0005099 name: carboxylic acid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out)." [GOC:mlg] xref: GO:0033284 is_a: CCO:F0005098 ! organic acid-transporting ATPase activity is_a: CCO:F0006282 ! carboxylic acid transmembrane transporter activity [Term] id: CCO:F0005100 name: monocarboxylic acid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out)." [GOC:mlg] xref: GO:0033285 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity is_a: CCO:F0005099 ! carboxylic acid-transporting ATPase activity [Term] id: CCO:F0005101 name: ectoine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out)." [GOC:mlg] xref: GO:0033286 is_a: CCO:F0005100 ! monocarboxylic acid-transporting ATPase activity is_a: CCO:F0008120 ! ectoine transmembrane transporter activity [Term] id: CCO:F0005102 name: hydroxyectoine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of hydroxyectoine from one side of the membrane to the other." [GOC:mlg] xref: GO:0033287 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0005103 name: hydroxyectoine-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out)." [GOC:mlg] xref: GO:0033288 is_a: CCO:F0005100 ! monocarboxylic acid-transporting ATPase activity is_a: CCO:F0005102 ! hydroxyectoine transmembrane transporter activity [Term] id: CCO:F0005104 name: monocarboxylic acid binding namespace: molecular_function def: "Interacting selectively with a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:mah] subset: gosubset_prok xref: GO:0033293 is_a: CCO:F0004660 ! carboxylic acid binding [Term] id: CCO:F0005105 name: ectoine binding namespace: molecular_function def: "Interacting selectively with ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid." [GOC:mah] xref: GO:0033294 is_a: CCO:F0005104 ! monocarboxylic acid binding [Term] id: CCO:F0005106 name: hydroxyectoine binding namespace: molecular_function def: "Interacting selectively with hydroxyectoine." [GOC:mlg] xref: GO:0033295 is_a: CCO:F0005104 ! monocarboxylic acid binding [Term] id: CCO:F0005107 name: rhamnose binding namespace: molecular_function def: "Interacting selectively with the D- or L-enantiomer of rhamnose." [GOC:mah] subset: gosubset_prok xref: GO:0033296 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0005108 name: rhamnose-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + rhamnose(out/in) = ADP + phosphate + rhamnose(in/out)." [GOC:mlg] xref: GO:0033297 is_a: CCO:F0002630 ! rhamnose transmembrane transporter activity is_a: CCO:F0002827 ! monosaccharide-transporting ATPase activity [Term] id: CCO:F0005109 name: dehydroascorbic acid transporter activity namespace: molecular_function def: "Enables the directed movement of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, into, out of, within or between cells." [ChEBI:17242] synonym: "dehydroascorbate transporter activity" EXACT [] xref: GO:0033300 is_a: CCO:F0008065 ! vitamin transporter activity [Term] id: CCO:F0005110 name: peroxisome membrane targeting sequence binding namespace: molecular_function def: "Interacting selectively with a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane." [GOC:rb, PMID:15133130] synonym: "mPTS binding" EXACT [] xref: GO:0033328 is_a: CCO:F0000054 ! peroxisome targeting sequence binding [Term] id: CCO:F0005111 name: actin homodimerization activity namespace: molecular_function def: "Interacting selectively with an identical actin monomer to form a homodimer." [GOC:mah] subset: gosubset_prok synonym: "actin dimerization activity" BROAD [] synonym: "actin polymerizing activity" RELATED [] xref: GO:0033392 is_a: CCO:F0005714 ! protein homodimerization activity [Term] id: CCO:F0005112 name: TTT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TTT codon." [GOC:mah] comment: Note that in the standard genetic code, TTT codes for phenylalanine. xref: GO:0033401 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005113 name: TTC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TTC codon." [GOC:mah] comment: Note that in the standard genetic code, TTC codes for phenylalanine. xref: GO:0033402 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005114 name: TTA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TTA codon." [GOC:mah] comment: Note that in the standard genetic code, TTA codes for leucine. xref: GO:0033403 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005115 name: TTG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TTG codon." [GOC:mah] comment: Note that in the standard genetic code, TTG codes for leucine. xref: GO:0033404 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005116 name: TCT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TCT codon." [GOC:mah] comment: Note that in the standard genetic code, TCT codes for serine. xref: GO:0033405 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005117 name: TCC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TCC codon." [GOC:mah] comment: Note that in the standard genetic code, TCC codes for serine. xref: GO:0033406 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005118 name: TCA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TCA codon." [GOC:mah] comment: Note that in the standard genetic code, TCA codes for serine. xref: GO:0033407 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005119 name: TCG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TCG codon." [GOC:mah] comment: Note that in the standard genetic code, TCG codes for serine. xref: GO:0033408 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005120 name: TAT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TAT codon." [GOC:mah] comment: Note that in the standard genetic code, TAT codes for tyrosine. xref: GO:0033409 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005121 name: TAC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TAC codon." [GOC:mah] comment: Note that in the standard genetic code, TAC codes for tyrosine. xref: GO:0033410 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005122 name: TAA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TAA codon." [GOC:mah] comment: Note that in the standard genetic code, TAA is a stop codon (ochre) and is not normally read by a tRNA. xref: GO:0033411 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005123 name: TAG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TAG codon." [GOC:mah] comment: Note that in the standard genetic code, TAG is a stop codon (amber) and is not normally read by a tRNA. xref: GO:0033412 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005124 name: TGT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TGT codon." [GOC:mah] comment: Note that in the standard genetic code, TGT codes for cysteine. xref: GO:0033413 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005125 name: TGC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TGC codon." [GOC:mah] comment: Note that in the standard genetic code, TGC codes for cysteine. xref: GO:0033414 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005126 name: TGA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TGA codon." [GOC:mah] comment: Note that in the standard genetic code, TGA is a stop codon (opal) and is not normally read by a tRNA. xref: GO:0033415 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005127 name: TGG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a TGG codon." [GOC:mah] comment: Note that in the standard genetic code, TGG codes for tryptophan. xref: GO:0033416 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005128 name: CTT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CTT codon." [GOC:mah] comment: Note that in the standard genetic code, CTT codes for leucine. xref: GO:0033417 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005129 name: CTC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CTC codon." [GOC:mah] comment: Note that in the standard genetic code, CTC codes for leucine. xref: GO:0033418 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005130 name: CTA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CTA codon." [GOC:mah] comment: Note that in the standard genetic code, CTA codes for leucine. xref: GO:0033419 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005131 name: CTG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CTG codon." [GOC:mah] comment: Note that in the standard genetic code, CTG codes for leucine. xref: GO:0033420 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005132 name: CCT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CCT codon." [GOC:mah] comment: Note that in the standard genetic code, CCT codes for proline. xref: GO:0033421 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005133 name: CCC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CCC codon." [GOC:mah] comment: Note that in the standard genetic code, CCC codes for proline. xref: GO:0033422 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005134 name: CCA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CCA codon." [GOC:mah] comment: Note that in the standard genetic code, CCA codes for proline. xref: GO:0033423 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005135 name: CCG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CCG codon." [GOC:mah] comment: Note that in the standard genetic code, CCG codes for proline. xref: GO:0033424 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005136 name: CAT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CAT codon." [GOC:mah] comment: Note that in the standard genetic code, CAT codes for histidine. xref: GO:0033425 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005137 name: CAC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CAC codon." [GOC:mah] comment: Note that in the standard genetic code, CAC codes for histidine. xref: GO:0033426 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005138 name: CAA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CAA codon." [GOC:mah] comment: Note that in the standard genetic code, CAA codes for glutamine. xref: GO:0033427 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005139 name: CAG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CAG codon." [GOC:mah] comment: Note that in the standard genetic code, CAG codes for glutamine. xref: GO:0033428 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005140 name: CGT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CGT codon." [GOC:mah] comment: Note that in the standard genetic code, CGT codes for arginine. xref: GO:0033429 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005141 name: CGC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CGC codon." [GOC:mah] comment: Note that in the standard genetic code, CGC codes for arginine. xref: GO:0033430 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005142 name: CGA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CGA codon." [GOC:mah] comment: Note that in the standard genetic code, CGA codes for arginine. xref: GO:0033431 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005143 name: CGG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a CGG codon." [GOC:mah] comment: Note that in the standard genetic code, CGG codes for arginine. xref: GO:0033432 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005144 name: ATT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ATT codon." [GOC:mah] comment: Note that in the standard genetic code, ATT codes for isoleucine. xref: GO:0033433 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005145 name: ATC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ATC codon." [GOC:mah] comment: Note that in the standard genetic code, ATC codes for isoleucine. xref: GO:0033434 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005146 name: ATA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ATA codon." [GOC:mah] comment: Note that in the standard genetic code, ATA codes for isoleucine. xref: GO:0033435 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005147 name: ATG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ATG codon." [GOC:mah] comment: Note that in the standard genetic code, ATG codes for methionine, and is the initiator codon. xref: GO:0033436 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005148 name: ACT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ACT codon." [GOC:mah] comment: Note that in the standard genetic code, ACT codes for threonine. xref: GO:0033437 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005149 name: ACC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ACC codon." [GOC:mah] comment: Note that in the standard genetic code, ACC codes for threonine. xref: GO:0033438 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005150 name: ACA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ACA codon." [GOC:mah] comment: Note that in the standard genetic code, ACA codes for threonine. xref: GO:0033439 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005151 name: ACG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an ACG codon." [GOC:mah] comment: Note that in the standard genetic code, ACG codes for threonine. xref: GO:0033440 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005152 name: AAT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AAT codon." [GOC:mah] comment: Note that in the standard genetic code, AAT codes for asparagine. xref: GO:0033441 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005153 name: AAC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AAC codon." [GOC:mah] comment: Note that in the standard genetic code, AAC codes for asparagine. xref: GO:0033442 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005154 name: AAA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AAA codon." [GOC:mah] comment: Note that in the standard genetic code, AAA codes for lysine. xref: GO:0033443 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005155 name: AAG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AAG codon." [GOC:mah] comment: Note that in the standard genetic code, AAG codes for lysine. xref: GO:0033444 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005156 name: AGT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AGT codon." [GOC:mah] comment: Note that in the standard genetic code, AGT codes for serine. xref: GO:0033445 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005157 name: AGC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AGC codon." [GOC:mah] comment: Note that in the standard genetic code, AGC codes for serine. xref: GO:0033446 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005158 name: AGA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AGA codon." [GOC:mah] comment: Note that in the standard genetic code, AGA codes for arginine. xref: GO:0033447 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005159 name: AGG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes an AGG codon." [GOC:mah] comment: Note that in the standard genetic code, AGG codes for arginine. xref: GO:0033448 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005160 name: GTT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GTT codon." [GOC:mah] comment: Note that in the standard genetic code, GTT codes for valine. xref: GO:0033449 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005161 name: GTC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GTC codon." [GOC:mah] comment: Note that in the standard genetic code, GTC codes for valine. xref: GO:0033450 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005162 name: GTA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GTA codon." [GOC:mah] comment: Note that in the standard genetic code, GTA codes for valine. xref: GO:0033451 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005163 name: GTG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GTG codon." [GOC:mah] comment: Note that in the standard genetic code, GTG codes for valine. xref: GO:0033452 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005164 name: GCT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GCT codon." [GOC:mah] comment: Note that in the standard genetic code, GCT codes for alanine. xref: GO:0033453 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005165 name: GCC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GCC codon." [GOC:mah] comment: Note that in the standard genetic code, GCC codes for alanine. xref: GO:0033454 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005166 name: GCA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GCA codon." [GOC:mah] comment: Note that in the standard genetic code, GCA codes for alanine. xref: GO:0033455 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005167 name: GCG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GCG codon." [GOC:mah] comment: Note that in the standard genetic code, GCG codes for alanine. xref: GO:0033456 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005168 name: GAT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GAT codon." [GOC:mah] comment: Note that in the standard genetic code, GAT codes for acid. xref: GO:0033457 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005169 name: GAC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GAC codon." [GOC:mah] comment: Note that in the standard genetic code, GAC codes for acid. xref: GO:0033458 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005170 name: GAA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GAA codon." [GOC:mah] comment: Note that in the standard genetic code, GAA codes for acid. xref: GO:0033459 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005171 name: GAG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GAG codon." [GOC:mah] comment: Note that in the standard genetic code, GAG codes for acid. xref: GO:0033460 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005172 name: GGT codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GGT codon." [GOC:mah] comment: Note that in the standard genetic code, GGT codes for glycine. xref: GO:0033461 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005173 name: GGC codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GGC codon." [GOC:mah] comment: Note that in the standard genetic code, GGC codes for glycine. xref: GO:0033462 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005174 name: GGA codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GGA codon." [GOC:mah] comment: Note that in the standard genetic code, GGA codes for glycine. xref: GO:0033463 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005175 name: GGG codon-amino acid adaptor activity namespace: molecular_function def: "A triplet codon-amino acid adaptor activity that recognizes a GGG codon." [GOC:mah] comment: Note that in the standard genetic code, GGG codes for glycine. xref: GO:0033464 is_a: CCO:F0004455 ! triplet codon-amino acid adaptor activity [Term] id: CCO:F0005176 name: MAP kinase phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate." [GOC:mah] xref: GO:0033549 is_a: CCO:F0001086 ! phosphoprotein phosphatase activity [Term] id: CCO:F0005177 name: MAP kinase tyrosine phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate." [GOC:mah] synonym: "tyrosine-specific MAP kinase phosphatase activity" EXACT [] xref: GO:0033550 is_a: CCO:F0001090 ! protein tyrosine phosphatase activity is_a: CCO:F0005176 ! MAP kinase phosphatase activity [Term] id: CCO:F0005178 name: dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol." [GOC:mah, PMID:10336995] synonym: "dolichyl-P-Glc:Man7GlcNAc2-PP-dolichyl glucosyltransferase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0033556 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005179 name: protein deacetylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate." [GOC:mah] xref: GO:0033558 is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0005180 name: folate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+." [GOC:pd] subset: gosubset_prok xref: GO:0033560 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005181 name: lactoferrin receptor activity namespace: molecular_function def: "Combining with lactoferrin to initiate a change in cell activity." [GOC:mlg] xref: GO:0033568 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0005182 name: lactoferrin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of lactoferrin from one side of a membrane to the other." [GOC:mlg] xref: GO:0033569 is_a: CCO:F0002571 ! ferric iron transmembrane transporter activity is_a: CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity [Term] id: CCO:F0005183 name: transferrin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of transferrin from one side of a membrane to the other." [GOC:mlg] xref: GO:0033570 is_a: CCO:F0002571 ! ferric iron transmembrane transporter activity is_a: CCO:F0002860 ! P-P-bond-hydrolysis-driven protein transmembrane transporter activity [Term] id: CCO:F0005184 name: RNA strand annealing activity namespace: molecular_function def: "Facilitates the base-pairing of complementary single-stranded RNA." [GOC:mah] xref: GO:0033592 is_a: CCO:F0000310 ! double-stranded RNA binding is_a: CCO:F0000312 ! single-stranded RNA binding [Term] id: CCO:F0005185 name: formyl-CoA transferase activity namespace: molecular_function def: "Catalysis of the reaction formyl-CoA + oxalate = formate + oxalyl-CoA." [EC:2.8.3.16, GOC:mlg] synonym: "formyl-CoA oxalate CoA-transferase activity" EXACT [EC:2.8.3.16] synonym: "formyl-CoA:oxalate CoA-transferase activity" EXACT [EC:2.8.3.16] synonym: "formyl-coenzyme A transferase activity" EXACT [EC:2.8.3.16] xref: EC:2.8.3.16 xref: GO:0033608 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0005186 name: receptor serine/threonine kinase binding namespace: molecular_function def: "Interacting selectively with a receptor that possesses protein serine/threonine kinase activity." [GOC:mah] synonym: "transmembrane receptor protein serine/threonine kinase ligand binding" RELATED [] xref: GO:0033612 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005187 name: transcription activator binding namespace: molecular_function def: "Interacting selectively with a transcription activator, any protein whose activity is required to initiate or upregulate transcription." [GOC:mah] xref: GO:0033613 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005188 name: double-stranded DNA-dependent ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of double-stranded DNA; drives another reaction." [GOC:mah] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "dsDNA-dependent ATPase activity" EXACT [] xref: GO:0033676 is_a: CCO:F0001707 ! DNA-dependent ATPase activity [Term] id: CCO:F0005189 name: DNA/RNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA." [GOC:mah] comment: Consider also annotating to the molecular function term 'RNA binding ; GO:0003723'. subset: gosubset_prok xref: EC:2.7.7.- xref: GO:0033677 xref: Reactome:7008 is_a: CCO:F0000803 ! helicase activity [Term] id: CCO:F0005190 name: 5'-3' DNA/RNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of a DNA/RNA duplex in the direction 5' to 3'." [GOC:mah] synonym: "5' to 3' DNA/RNA helicase activity" EXACT [] xref: GO:0033678 is_a: CCO:F0005189 ! DNA/RNA helicase activity [Term] id: CCO:F0005191 name: 3'-5' DNA/RNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of a DNA/RNA duplex in the direction 3' to 5'." [GOC:mah] synonym: "3' to 5' DNA/RNA helicase activity" EXACT [] xref: GO:0033679 is_a: CCO:F0005189 ! DNA/RNA helicase activity [Term] id: CCO:F0005192 name: ATP-dependent DNA/RNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of a DNA/RNA duplex." [GOC:mah] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok xref: GO:0033680 is_a: CCO:F0001682 ! ATP-dependent helicase activity is_a: CCO:F0001707 ! DNA-dependent ATPase activity is_a: CCO:F0005189 ! DNA/RNA helicase activity [Term] id: CCO:F0005193 name: ATP-dependent 3'-5' DNA/RNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of a DNA/RNA duplex in the direction 3' to 5'." [GOC:mah] synonym: "ATP-dependent 3' to 5' DNA/RNA helicase activity" EXACT [] xref: GO:0033681 is_a: CCO:F0005191 ! 3'-5' DNA/RNA helicase activity is_a: CCO:F0005192 ! ATP-dependent DNA/RNA helicase activity [Term] id: CCO:F0005194 name: ATP-dependent 5'-3' DNA/RNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of a DNA/RNA duplex in the direction 5' to 3'." [GOC:mah] synonym: "ATP-dependent 5' to 3' DNA/RNA helicase activity" EXACT [] xref: GO:0033682 is_a: CCO:F0005190 ! 5'-3' DNA/RNA helicase activity is_a: CCO:F0005192 ! ATP-dependent DNA/RNA helicase activity [Term] id: CCO:F0005195 name: sialic acid binding namespace: molecular_function def: "Interacting selectively with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria." [GOC:add, http:en.wikipedia.org, http:www.biology-online.org, ISBN:0721601465] synonym: "N-acetylneuraminic acid binding" NARROW [] xref: GO:0033691 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0005196 name: oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl] subset: gosubset_prok xref: EC:1.5.7 xref: GO:0033694 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0005197 name: oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule." [EC:1.17.5, GOC:mah] subset: gosubset_prok xref: EC:1.17.5 xref: GO:0033695 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0005198 name: DNA 5'-adenosine monophosphate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus." [GOC:mah, PMID:16547001, PMID:17276982] synonym: "AMP-removal activity" RELATED [] synonym: "DNA 5'-adenylate hydrolase activity" EXACT [] synonym: "DNA adenylate hydrolysis activity" BROAD [] synonym: "DNA de-adenylation" RELATED [] synonym: "DNA deadenylation" RELATED [] xref: GO:0033699 is_a: CCO:F0005595 ! 5'-3' exodeoxyribonuclease activity [Term] id: CCO:F0005199 name: dTDP-galactose 6-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+." [EC:1.1.1.186] synonym: "dTDP-D-galactose:NADP+ 6-oxidoreductase activity" EXACT [EC:1.1.1.186] synonym: "dTDPgalactose 6-dehydrogenase activity" EXACT [EC:1.1.1.186] synonym: "thymidine-diphosphate-galactose dehydrogenase activity" EXACT [EC:1.1.1.186] xref: EC:1.1.1.186 xref: GO:0033701 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005201 name: 3beta-hydroxy-5beta-steroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP+ = 5beta-pregnan-3,20-dione + NADPH + H+." [EC:1.1.1.277] synonym: "3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.277] synonym: "3beta-hydroxysteroid 5beta-oxidoreductase activity" EXACT [EC:1.1.1.277] synonym: "3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity" EXACT [EC:1.1.1.277] xref: EC:1.1.1.277 xref: GO:0033703 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005202 name: 3beta-hydroxy-5alpha-steroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP+ = 5alpha-pregnan-3,20-dione + NADPH + H+." [EC:1.1.1.278] synonym: "3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.278] xref: EC:1.1.1.278 xref: GO:0033704 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005203 name: GDP-4-dehydro-6-deoxy-D-mannose reductase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+." [EC:1.1.1.281] comment: Note that this enzyme differs from EC 1.1.1.187, GDP-4-dehydro-D-rhamnose reductase, in that the only product formed is GDP-D-rhamnose (GDP-6-deoxy-D-mannose). synonym: "GDP-4-keto-6-deoxy-D-mannose reductase activity" BROAD [EC:1.1.1.281] synonym: "GDP-6-deoxy-D-lyxo-4-hexulose reductase activity" EXACT [EC:1.1.1.281] synonym: "GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming) activity" EXACT [EC:1.1.1.281] synonym: "Rmd" RELATED [EC:1.1.1.281] xref: EC:1.1.1.281 xref: GO:0033705 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005204 name: quinate/shikimate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reactions: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+ and shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+." [EC:1.1.1.282] synonym: "L-quinate:NAD(P)+ 3-oxidoreductase activity" EXACT [EC:1.1.1.282] synonym: "YdiB" RELATED [EC:1.1.1.282] xref: EC:1.1.1.282 xref: GO:0033706 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005205 name: 3''-deamino-3''-oxonicotianamine reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+." [EC:1.1.1.285] synonym: "2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity" EXACT [EC:1.1.1.285] xref: EC:1.1.1.285 xref: GO:0033707 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005206 name: isocitrate-homoisocitrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+." [EC:1.1.1.286] synonym: "homoisocitrate-isocitrate dehydrogenase activity" EXACT [EC:1.1.1.286] synonym: "isocitrate(homoisocitrate):NAD+ oxidoreductase (decarboxylating) activity" EXACT [EC:1.1.1.286] synonym: "PH1722" RELATED [EC:1.1.1.286] xref: EC:1.1.1.286 xref: GO:0033708 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005207 name: D-arabinitol dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reactions: D-arabinitol + NADP+ = D-xylulose + NADPH + H+ and D-arabinitol + NADP+ = D-ribulose + NADPH + H+." [EC:1.1.1.287] synonym: "ARD1p" RELATED [EC:1.1.1.287] synonym: "D-arabinitol dehydrogenase 1 activity" NARROW [EC:1.1.1.287] synonym: "D-arabinitol:NADP+ dehydrogenase activity" EXACT [EC:1.1.1.287] synonym: "NADP+-dependent D-arabinitol dehydrogenase activity" EXACT [EC:1.1.1.287] xref: EC:1.1.1.287 xref: GO:0033709 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005208 name: 4-phosphoerythronate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-phospho-D-erythronate + NAD+ = (3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + NADH + H+." [EC:1.1.1.290] synonym: "4-O-phosphoerythronate dehydrogenase activity" EXACT [EC:1.1.1.290] synonym: "4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.290] synonym: "4PE dehydrogenase activity" EXACT [EC:1.1.1.290] synonym: "erythronate-4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.290] synonym: "PdxB" RELATED [EC:1.1.1.290] synonym: "PdxB 4PE dehydrogenase activity" EXACT [EC:1.1.1.290] xref: EC:1.1.1.290 xref: GO:0033711 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005209 name: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity namespace: molecular_function def: "Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + NADPH + H+." [EC:1.1.1.292] synonym: "1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.292] synonym: "AFR" RELATED [EC:1.1.1.292] xref: EC:1.1.1.292 xref: GO:0033712 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005210 name: choline:oxygen 1-oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: choline + O2 = betaine aldehyde + H2O2." [EC:1.1.3.17] synonym: "choline oxidase activity" BROAD [EC:1.1.3.17] xref: EC:1.1.3.17 xref: GO:0033713 is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0005211 name: secondary-alcohol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: a secondary alcohol + O2 = a ketone + H2O2." [EC:1.1.3.18] synonym: "polyvinyl alcohol oxidase activity" EXACT [EC:1.1.3.18] synonym: "secondary alcohol oxidase activity" EXACT [EC:1.1.3.18] synonym: "secondary-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.18] xref: EC:1.1.3.18 xref: GO:0033714 is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0005212 name: nucleoside oxidase activity namespace: molecular_function def: "Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O and (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O." [EC:1.1.3.28] synonym: "nucleoside:oxygen 5'-oxidoreductase activity" EXACT [EC:1.1.3.28] xref: EC:1.1.3.28 xref: GO:0033715 is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0005213 name: nucleoside oxidase (H2O2-forming) activity namespace: molecular_function def: "Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 H2O2, (1a) adenosine + O2 = 5'-dehydroadenosine + H2O2 and (1b) 5'-dehydroadenosine + O2 = 9-riburonosyladenine + H2O2." [EC:1.1.3.39] synonym: "nucleoside:oxygen 5'-oxidoreductase (H2O2-forming) activity" EXACT [EC:1.1.3.39] xref: EC:1.1.3.39 xref: GO:0033716 is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0005214 name: gluconate 2-dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor." [EC:1.1.99.3] synonym: "2-ketogluconate reductase activity" BROAD [EC:1.1.99.3] synonym: "D-gluconate dehydrogenase activity" EXACT [EC:1.1.99.3] synonym: "D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity" EXACT [EC:1.1.99.3] synonym: "D-gluconate:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.1.99.3] synonym: "D-gluconate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.3] synonym: "gluconate oxidase activity" EXACT [EC:1.1.99.3] synonym: "gluconic acid dehydrogenase activity" EXACT [EC:1.1.99.3] synonym: "gluconic dehydrogenase activity" EXACT [EC:1.1.99.3] xref: EC:1.1.99.3 xref: GO:0033717 is_a: CCO:F0002213 ! gluconate dehydrogenase activity [Term] id: CCO:F0005215 name: pyranose dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor." [EC:1.1.99.29] synonym: "PDH" RELATED [EC:1.1.99.29] synonym: "pyranose dehydrogenase activity" EXACT [EC:1.1.99.29] synonym: "pyranose-quinone oxidoreductase activity" EXACT [EC:1.1.99.29] synonym: "pyranose:acceptor oxidoreductase activity" EXACT [EC:1.1.99.29] synonym: "quinone-dependent pyranose dehydrogenase activity" EXACT [EC:1.1.99.29] xref: EC:1.1.99.29 xref: GO:0033718 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0005216 name: 2-oxo-acid reductase activity namespace: molecular_function def: "Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor." [EC:1.1.99.30] synonym: "(2R)-hydroxy-carboxylate:acceptor oxidoreductase activity" EXACT [EC:1.1.99.30] synonym: "(2R)-hydroxycarboxylate-viologen-oxidoreductase activity" EXACT [EC:1.1.99.30] synonym: "2-oxoacid reductase activity" EXACT [EC:1.1.99.30] synonym: "HVOR" RELATED [EC:1.1.99.30] xref: EC:1.1.99.30 xref: GO:0033719 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0005218 name: aldehyde dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+." [EC:1.2.1.4] synonym: "aldehyde:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.4] synonym: "NADP-acetaldehyde dehydrogenase activity" EXACT [EC:1.2.1.4] synonym: "NADP-dependent aldehyde dehydrogenase activity" EXACT [EC:1.2.1.4] xref: EC:1.2.1.4 xref: GO:0033721 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005219 name: malonate-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+." [EC:1.2.1.15] synonym: "3-oxopropanoate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.15] synonym: "malonic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.15] xref: EC:1.2.1.15 xref: GO:0033722 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005220 name: fluoroacetaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+." [EC:1.2.1.69] synonym: "fluoroacetaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.69] xref: EC:1.2.1.69 xref: GO:0033723 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005221 name: aldehyde ferredoxin oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin." [EC:1.2.7.5] synonym: "aldehyde:ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.5] synonym: "AOR" RELATED [EC:1.2.7.5] synonym: "tungsten-containing aldehyde ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.5] xref: EC:1.2.7.5 xref: GO:0033726 is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0005222 name: aldehyde dehydrogenase (FAD-independent) activity namespace: molecular_function def: "Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor." [EC:1.2.99.7] synonym: "aldehyde oxidoreductase activity" EXACT [EC:1.2.99.7] synonym: "aldehyde:acceptor oxidoreductase (FAD-independent) activity" EXACT [EC:1.2.99.7] synonym: "AORDd" RELATED [EC:1.2.99.7] synonym: "Mop" RELATED [EC:1.2.99.7] xref: EC:1.2.99.7 xref: GO:0033727 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0005223 name: divinyl chlorophyllide a 8-vinyl-reductase activity namespace: molecular_function def: "Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+." [EC:1.3.1.75] synonym: "4VCR" RELATED [EC:1.3.1.75] synonym: "[4-vinyl]chlorophyllide a reductase activity" EXACT [EC:1.3.1.75] synonym: "chlorophyllide-a:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.75] xref: EC:1.3.1.75 xref: GO:0033728 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005224 name: anthocyanidin reductase activity namespace: molecular_function def: "Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+." [EC:1.3.1.77] synonym: "ANR" RELATED [EC:1.3.1.77] synonym: "AtANR" RELATED [EC:1.3.1.77] synonym: "flavan-3-ol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.3.1.77] synonym: "MtANR" RELATED [EC:1.3.1.77] xref: EC:1.3.1.77 xref: GO:0033729 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005225 name: arogenate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2." [EC:1.3.1.78] synonym: "arogenic dehydrogenase activity" BROAD [EC:1.3.1.78] synonym: "L-arogenate:NADP+ oxidoreductase (decarboxylating) activity" EXACT [EC:1.3.1.78] synonym: "pretyrosine dehydrogenase activity" BROAD [EC:1.3.1.78] synonym: "TyrAa" RELATED [EC:1.3.1.78] synonym: "TyrAAT1" RELATED [EC:1.3.1.78] synonym: "TyrAAT2" RELATED [EC:1.3.1.78] xref: EC:1.3.1.78 xref: GO:0033730 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005226 name: arogenate dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2." [EC:1.3.1.79] synonym: "arogenic dehydrogenase activity" BROAD [EC:1.3.1.79] synonym: "L-arogenate:NAD(P)+ oxidoreductase (decarboxylating) activity" EXACT [EC:1.3.1.79] synonym: "pretyrosine dehydrogenase activity" BROAD [EC:1.3.1.79] xref: EC:1.3.1.79 xref: GO:0033731 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005227 name: pyrroloquinoline-quinone synthase activity namespace: molecular_function def: "Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-3a,4,5,6,7,8,9,9b-octahydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O." [EC:1.3.3.11] synonym: "6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity" EXACT [EC:1.3.3.11] synonym: "PqqC" RELATED [EC:1.3.3.11] xref: EC:1.3.3.11 xref: GO:0033732 is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0005229 name: aspartate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+." [EC:1.4.1.21] synonym: "L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity" EXACT [EC:1.4.1.21] synonym: "NAD-dependent aspartate dehydrogenase activity" EXACT [EC:1.4.1.21] synonym: "NADH2-dependent aspartate dehydrogenase activity" EXACT [EC:1.4.1.21] synonym: "NADP+-dependent aspartate dehydrogenase activity" EXACT [EC:1.4.1.21] xref: EC:1.4.1.21 xref: GO:0033735 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0005230 name: L-lysine 6-oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine + O2 + H2O = 2-aminoadipate 6-semialdehyde + H2O2 + NH3." [EC:1.4.3.20] synonym: "L-lysine-epsilon-oxidase activity" EXACT [EC:1.4.3.20] synonym: "L-lysine:oxygen 6-oxidoreductase (deaminating) activity" EXACT [EC:1.4.3.20] synonym: "Lod" RELATED [EC:1.4.3.20] synonym: "LodA" RELATED [EC:1.4.3.20] synonym: "marinocine" RELATED [EC:1.4.3.20] xref: EC:1.4.3.20 xref: GO:0033736 is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0005231 name: 1-pyrroline dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+." [EC:1.5.1.35] synonym: "1-pyrroline:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.35] synonym: "ABALDH" RELATED [EC:1.5.1.35] synonym: "gamma-aminobutyraldehyde dehydrogenase activity" EXACT [EC:1.5.1.35] synonym: "YdcW" RELATED [EC:1.5.1.35] xref: EC:1.5.1.35 xref: GO:0033737 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005232 name: methylenetetrahydrofolate reductase (ferredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin." [EC:1.5.7.1] synonym: "5,10-methylenetetrahydrofolate reductase activity" BROAD [EC:1.5.7.1] synonym: "5-methyltetrahydrofolate:ferredoxin oxidoreductase activity" EXACT [EC:1.5.7.1] xref: EC:1.5.7.1 xref: GO:0033738 is_a: CCO:F0005196 ! oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0005233 name: queuine synthase activity namespace: molecular_function def: "Catalysis of the reaction: queuine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH + 2 H+." [EC:1.7.1.13] synonym: "7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.13] synonym: "7-cyano-7-deazaguanine reductase activity" EXACT [EC:1.7.1.13] synonym: "preQ0 oxidoreductase activity" EXACT [EC:1.7.1.13] synonym: "preQ0 reductase activity" EXACT [EC:1.7.1.13] synonym: "QueF" RELATED [EC:1.7.1.13] synonym: "queuine:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.13] synonym: "YkvM" RELATED [EC:1.7.1.13] xref: EC:1.7.1.13 xref: GO:0033739 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0005234 name: hydroxylamine oxidoreductase activity namespace: molecular_function def: "Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O and hydrazine + acceptor = N2 + reduced acceptor." [EC:1.7.99.8] synonym: "hydroxylamine:acceptor oxidoreductase activity" EXACT [EC:1.7.99.8] xref: EC:1.7.99.8 xref: GO:0033740 is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005235 name: adenylyl-sulfate reductase (glutathione) activity namespace: molecular_function def: "Catalysis of the reaction: AMP + sulfite + glutathione disulfide = adenylyl sulfate + 2 glutathione." [EC:1.8.4.9] synonym: "5'-adenylylsulfate reductase activity" EXACT [EC:1.8.4.9] synonym: "AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity" EXACT [EC:1.8.4.9] synonym: "AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity" EXACT [EC:1.8.4.9] synonym: "plant-type 5'-adenylylsulfate reductase activity" NARROW [EC:1.8.4.9] xref: EC:1.8.4.9 xref: GO:0033741 is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0005236 name: peptide-methionine (R)-S-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin." [EC:1.8.4.12] synonym: "methionine S-oxide reductase (R-form oxidizing) activity" EXACT [EC:1.8.4.12] synonym: "methionine S-oxide reductase activity" BROAD [EC:1.8.4.12] synonym: "methionine sulfoxide reductase activity" BROAD [EC:1.8.4.12] synonym: "methionine sulfoxide reductase B activity" NARROW [EC:1.8.4.12] synonym: "MsrB" RELATED [EC:1.8.4.12] synonym: "peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity" EXACT [EC:1.8.4.12] synonym: "PilB" RELATED [EC:1.8.4.12] synonym: "pMRsr" RELATED [EC:1.8.4.12] synonym: "pMSR" RELATED [EC:1.8.4.12] synonym: "selenoprotein R" RELATED [EC:1.8.4.12] synonym: "SelR" RELATED [EC:1.8.4.12] synonym: "SelX" RELATED [EC:1.8.4.12] xref: EC:1.8.4.12 xref: GO:0033743 is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0005237 name: L-methionine-(S)-S-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin." [EC:1.8.4.13] synonym: "acetylmethionine sulfoxide reductase activity" EXACT [EC:1.8.4.13] synonym: "free-methionine (S)-S-oxide reductase activity" EXACT [EC:1.8.4.13] synonym: "fSMsr" RELATED [EC:1.8.4.13] synonym: "L-methionine:oxidized-thioredoxin S-oxidoreductase activity" EXACT [EC:1.8.4.13] synonym: "L-methionine:thioredoxin-disulfide S-oxidoreductase activity" EXACT [EC:1.8.4.13] synonym: "methionine sulfoxide reductase activity" BROAD [EC:1.8.4.13] synonym: "methyl sulfoxide reductase I and II activity" EXACT [EC:1.8.4.13] xref: EC:1.8.4.13 xref: GO:0033744 is_a: CCO:F0000066 ! methionine-S-oxide reductase activity [Term] id: CCO:F0005238 name: L-methionine-(R)-S-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin." [EC:1.8.4.14] synonym: "free met-R-(o) reductase activity" EXACT [EC:1.8.4.14] synonym: "free-methionine (R)-S-oxide reductase activity" EXACT [EC:1.8.4.14] synonym: "fRMsr" RELATED [EC:1.8.4.14] synonym: "FRMsr" RELATED [EC:1.8.4.14] synonym: "L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity" EXACT [EC:1.8.4.14] xref: EC:1.8.4.14 xref: GO:0033745 is_a: CCO:F0000066 ! methionine-S-oxide reductase activity [Term] id: CCO:F0005239 name: histone demethylase activity (H3-R2 specific) namespace: molecular_function def: "Catalysis of the removal of a methyl group from arginine at position 2 of the histone H3 protein." [GOC:mah] xref: GO:0033746 is_a: CCO:F0004998 ! histone demethylase activity [Term] id: CCO:F0005240 name: versatile peroxidase activity namespace: molecular_function def: "Catalysis of the reactions: Reactive Black 5 + H2O2 = oxidized Reactive Black 5 + 2 H2O and donor + H2O2 = oxidized donor + 2 H2O." [EC:1.11.1.16] synonym: "hybrid peroxidase activity" EXACT [EC:1.11.1.16] synonym: "polyvalent peroxidase activity" EXACT [EC:1.11.1.16] synonym: "reactive-black-5:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.16] synonym: "VP" RELATED [EC:1.11.1.16] xref: EC:1.11.1.16 xref: GO:0033747 is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0005241 name: hydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: H2 + A = AH2." [EC:1.12.99.6] synonym: "H2 producing hydrogenase activity" BROAD [EC:1.12.99.6] synonym: "hydrogen-lyase activity" BROAD [EC:1.12.99.6] synonym: "hydrogen:(acceptor) oxidoreductase activity" EXACT [EC:1.12.99.6] synonym: "hydrogen:acceptor oxidoreductase activity" EXACT [EC:1.12.99.6] synonym: "hydrogenlyase activity" BROAD [EC:1.12.99.6] synonym: "uptake hydrogenase activity" BROAD [EC:1.12.99.6] xref: EC:1.12.99.6 xref: GO:0033748 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0005242 name: histone demethylase activity (H4-R3 specific) namespace: molecular_function def: "Catalysis of the removal of a methyl group from arginine at position 3 of the histone H4 protein." [GOC:mah] xref: GO:0033749 is_a: CCO:F0004998 ! histone demethylase activity [Term] id: CCO:F0005243 name: linoleate diol synthase activity namespace: molecular_function def: "Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate." [EC:1.13.11.44] synonym: "linoleate (8R)-dioxygenase activity" EXACT [EC:1.13.11.44] synonym: "linoleate 8-dioxygenase activity" EXACT [EC:1.13.11.44] synonym: "linoleate:oxygen 7S,8S-oxidoreductase activity" EXACT [EC:1.13.11.44] xref: EC:1.13.11.44 xref: GO:0033751 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0005244 name: acetylacetone-cleaving enzyme activity namespace: molecular_function def: "Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal." [EC:1.13.11.50] synonym: "acetylacetone dioxygenase activity" EXACT [EC:1.13.11.50] synonym: "acetylacetone-cleaving enzyme" RELATED [EC:1.13.11.50] synonym: "acetylacetone:oxygen oxidoreductase activity" EXACT [EC:1.13.11.50] synonym: "diketone cleaving dioxygenase activity" EXACT [EC:1.13.11.50] synonym: "diketone cleaving enzyme" RELATED [EC:1.13.11.50] synonym: "Dke1" RELATED [EC:1.13.11.50] xref: EC:1.13.11.50 xref: GO:0033752 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0005245 name: indoleamine 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine; includes both reactions D-tryptophan + O2 = N-formyl-D-kynurenine and L-tryptophan + O2 = N-formyl-L-kynurenine." [EC:1.13.11.52] synonym: "D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity" NARROW [EC:1.13.11.52] synonym: "IDO" RELATED [EC:1.13.11.52] synonym: "tryptophan pyrrolase activity" BROAD [EC:1.13.11.52] xref: EC:1.13.11.52 xref: GO:0033754 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0005246 name: sulfur oxygenase/reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+." [EC:1.13.11.55] synonym: "SOR" RELATED [EC:1.13.11.55] synonym: "sulfur oxygenase activity" BROAD [EC:1.13.11.55] synonym: "sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity" EXACT [EC:1.13.11.55] synonym: "sulphur oxygenase/reductase activity" EXACT [] xref: EC:1.13.11.55 xref: GO:0033755 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0005247 name: Oplophorus-luciferin 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu." [EC:1.13.12.13] synonym: "Oplophorus luciferase activity" EXACT [EC:1.13.12.13] synonym: "Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity" EXACT [EC:1.13.12.13] xref: EC:1.13.12.13 xref: GO:0033756 is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) is_a: CCO:F0006100 ! luciferin monooxygenase activity [Term] id: CCO:F0005248 name: glucoside 3-dehydrogenase namespace: molecular_function def: "Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor." [EC:1.1.99.13] synonym: "D-aldohexopyranoside dehydrogenase" EXACT [EC:1.1.99.13] synonym: "D-aldohexoside:(acceptor) 3-oxidoreductase" EXACT [EC:1.1.99.13] synonym: "D-aldohexoside:acceptor 3-oxidoreductase" EXACT [EC:1.1.99.13] synonym: "D-aldohexoside:cytochrome c oxidoreductase" EXACT [EC:1.1.99.13] synonym: "hexopyranoside-cytochrome c oxidoreductase" EXACT [EC:1.1.99.13] xref: EC:1.1.99.13 xref: GO:0033757 xref: MetaCyc:GLUCOSIDE-3-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0005249 name: clavaminate synthase activity namespace: molecular_function def: "Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O and proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O." [EC:1.14.11.21] synonym: "clavaminate synthase 2 activity" NARROW [EC:1.14.11.21] synonym: "clavaminic acid synthase activity" EXACT [EC:1.14.11.21] synonym: "deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.21] xref: EC:1.14.11.21 xref: GO:0033758 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0005250 name: flavone synthase activity namespace: molecular_function def: "Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O." [EC:1.14.11.22] synonym: "flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity" EXACT [EC:1.14.11.22] synonym: "flavone synthase I activity" EXACT [EC:1.14.11.22] synonym: "FNS I" RELATED [EC:1.14.11.22] xref: EC:1.14.11.22 xref: GO:0033759 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0005251 name: 2'-deoxymugineic-acid 2'-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = mugineic acid + succinate + CO2." [EC:1.14.11.24] synonym: "2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) activity" EXACT [EC:1.14.11.24] synonym: "IDS3" RELATED [EC:1.14.11.24] xref: EC:1.14.11.24 xref: GO:0033760 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0005252 name: mugineic-acid 3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2 and 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2." [EC:1.14.11.25] synonym: "IDS2" RELATED [EC:1.14.11.25] synonym: "mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.25] xref: EC:1.14.11.25 xref: GO:0033761 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0005253 name: proline 3-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2." [EC:1.14.11.28] synonym: "L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.28] synonym: "P-3-H" RELATED [EC:1.14.11.28] xref: EC:1.14.11.28 xref: GO:0033763 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0005254 name: steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative." [GOC:mah] subset: gosubset_prok xref: EC:1.1.1.- xref: GO:0033764 is_a: CCO:F0003082 ! steroid dehydrogenase activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005255 name: steroid dehydrogenase activity, acting on the CH-CH group of donors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative." [GOC:mah] subset: gosubset_prok xref: EC:1.1.1.- xref: GO:0033765 is_a: CCO:F0003082 ! steroid dehydrogenase activity is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0005256 name: 2-hydroxyquinoline 8-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = quinolin-2,8-diol + NAD+ + H2O." [EC:1.14.13.61] synonym: "2-oxo-1,2-dihydroquinoline 8-monooxygenase activity" EXACT [EC:1.14.13.61] synonym: "quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity" EXACT [EC:1.14.13.61] xref: EC:1.14.13.61 xref: GO:0033766 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005257 name: 4-hydroxyacetophenone monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (4-hydroxyphenyl)ethan-1-one + NADPH + H+ + O2 = 4-hydroxyphenyl acetate + NADP+ + H2O." [EC:1.14.13.80, EC:1.14.13.84] synonym: "(+)-limonene 6-monooxygenase activity" EXACT [EC:1.14.13.80] synonym: "(+)-limonene-6-hydroxylase activity" EXACT [EC:1.14.13.80] synonym: "(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity" EXACT [EC:1.14.13.84] synonym: "(R)-limonene 6-monooxygenase activity" EXACT [EC:1.14.13.80] synonym: "(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity" EXACT [EC:1.14.13.80] synonym: "HAPMO" RELATED [EC:1.14.13.84] xref: EC:1.14.13.80 xref: EC:1.14.13.84 xref: GO:0033767 xref: UM-BBD_enzymeID:e0479 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005258 name: glyceollin synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O." [EC:1.14.13.85] synonym: "2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,NADPH:oxygen oxidoreductase (cyclizing) activity" EXACT [EC:1.14.13.85] synonym: "dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity" EXACT [EC:1.14.13.85] xref: EC:1.14.13.85 xref: GO:0033769 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005259 name: 2-hydroxyisoflavanone synthase activity namespace: molecular_function def: "Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O." [EC:1.14.13.86] synonym: "2-HIS" RELATED [EC:1.14.13.86] synonym: "apigenin,NADPH:oxygen oxidoreductase (isoflavanone-forming) activity" EXACT [EC:1.14.13.86] xref: EC:1.14.13.86 xref: GO:0033770 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005260 name: licodione synthase activity namespace: molecular_function def: "Catalysis of the reaction: liquiritigenin + NADPH + H+ + O2 = licodione + NADP+ + H2O." [EC:1.14.13.87] synonym: "(2S)-flavanone 2-hydroxylase activity" EXACT [EC:1.14.13.87] synonym: "liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming) activity" EXACT [EC:1.14.13.87] xref: EC:1.14.13.87 xref: GO:0033771 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005261 name: flavonoid 3',5'-hydroxylase activity namespace: molecular_function def: "Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O." [EC:1.14.13.88] synonym: "F3',5'H" RELATED [EC:1.14.13.88] synonym: "F3'5'H" RELATED [EC:1.14.13.88] synonym: "flavanone,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.88] xref: EC:1.14.13.88 xref: GO:0033772 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005262 name: isoflavone 2'-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: an isoflavone + NADPH + H+ + O2 = a 2'-hydroxyisoflavone + NADP+ + H2O." [EC:1.14.13.89] synonym: "CYP Ge-3" RELATED [EC:1.14.13.89] synonym: "CYP81E1" RELATED [EC:1.14.13.89] synonym: "isoflavone 2'-monooxygenase activity" BROAD [EC:1.14.13.89] synonym: "isoflavone,NADPH:oxygen oxidoreductase (2'-hydroxylating) activity" EXACT [EC:1.14.13.89] xref: EC:1.14.13.89 xref: GO:0033773 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005263 name: deoxysarpagine hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 10-deoxysarpagine + NADPH + H+ + O2 = sarpagine + NADP+ + H2O." [EC:1.14.13.91] synonym: "10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity" EXACT [EC:1.14.13.91] synonym: "DOSH" RELATED [EC:1.14.13.91] xref: EC:1.14.13.91 xref: GO:0033775 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005264 name: phenylacetone monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phenylacetone + NADPH + H+ + O2 = benzyl acetate + NADP+ + H2O." [EC:1.14.13.92] synonym: "PAMO" RELATED [EC:1.14.13.92] synonym: "phenylacetone,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.92] xref: EC:1.14.13.92 xref: GO:0033776 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005265 name: lithocholate 6beta-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: lithocholate + NADPH + H+ + O2 = 6beta-hydroxylithocholate + NADP+ + H2O." [EC:1.14.13.94] synonym: "6beta-hydroxylase activity" BROAD [EC:1.14.13.94] synonym: "CYP3A10" RELATED [EC:1.14.13.94] synonym: "cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity" EXACT [EC:1.14.13.94] synonym: "lithocholate 6beta-monooxygenase activity" EXACT [EC:1.14.13.94] synonym: "lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity" EXACT [EC:1.14.13.94] xref: EC:1.14.13.94 xref: GO:0033777 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005266 name: 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O." [EC:1.14.13.95] synonym: "7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity" EXACT [EC:1.14.13.95] synonym: "7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity" EXACT [EC:1.14.13.95] synonym: "CYP12" RELATED [EC:1.14.13.95] synonym: "HCO 12alpha-hydroxylase activity" EXACT [EC:1.14.13.95] synonym: "sterol 12alpha-hydroxylase activity" BROAD [EC:1.14.13.95] xref: EC:1.14.13.95 xref: GO:0033778 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005267 name: 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + NADPH + H+ + O2 = 5beta-cholestane-3alpha,7alpha,12alpha-triol + NADP+ + H2O." [EC:1.14.13.96] synonym: "5beta-cholestane-3alpha,7alpha-diol 12alpha-monooxygenase activity" EXACT [EC:1.14.13.96] synonym: "5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity" EXACT [EC:1.14.13.96] synonym: "CYP8B1" RELATED [EC:1.14.13.96] synonym: "cytochrome P450 8B1" RELATED [EC:1.14.13.96] synonym: "sterol 12alpha-hydroxylase activity" BROAD [EC:1.14.13.96] xref: EC:1.14.13.96 xref: GO:0033779 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005268 name: taurochenodeoxycholate 6alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O." [EC:1.14.13.97] synonym: "CYP3A4" RELATED [EC:1.14.13.97] synonym: "CYP4A21" RELATED [EC:1.14.13.97] synonym: "taurochenodeoxycholate 6alpha-monooxygenase activity" EXACT [EC:1.14.13.97] synonym: "taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity" EXACT [EC:1.14.13.97] xref: EC:1.14.13.97 xref: GO:0033780 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005269 name: cholesterol 24-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = (24S)-24-hydroxycholesterol + NADP+ + H2O." [EC:1.14.13.98] synonym: "cholesterol 24-monooxygenase activity" EXACT [EC:1.14.13.98] synonym: "cholesterol 24S-hydroxylase activity" EXACT [EC:1.14.13.98] synonym: "cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity" EXACT [EC:1.14.13.98] synonym: "CYP46" RELATED [EC:1.14.13.98] synonym: "CYP46A1" RELATED [EC:1.14.13.98] synonym: "cytochrome P450 46A1" RELATED [EC:1.14.13.98] xref: EC:1.14.13.98 xref: GO:0033781 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005270 name: 24-hydroxycholesterol 7alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + NADPH + H+ + O2 = (24R)-cholest-5-ene-3beta,7alpha,24-triol + NADP+ + H2O." [EC:1.14.13.99] synonym: "(24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" EXACT [EC:1.14.13.99] synonym: "24-hydroxycholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.13.99] synonym: "CYP39A1" RELATED [EC:1.14.13.99] synonym: "CYP39A1 oxysterol 7alpha-hydroxylase activity" EXACT [EC:1.14.13.99] xref: EC:1.14.13.99 xref: GO:0033782 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005271 name: 25-hydroxycholesterol 7alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O." [EC:1.14.13.100] synonym: "25-hydroxycholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.13.100] synonym: "cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" EXACT [EC:1.14.13.100] synonym: "CYP7B1" RELATED [EC:1.14.13.100] synonym: "CYP7B1 oxysterol 7alpha-hydroxylase activity" EXACT [EC:1.14.13.100] xref: EC:1.14.13.100 xref: GO:0033783 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005272 name: senecionine N-oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: senecionine + NADPH + H+ + O2 = senecionine N-oxide + NADP+ + H2O." [EC:1.14.13.101] synonym: "senecionine monooxygenase (N-oxide-forming) activity" EXACT [EC:1.14.13.101] synonym: "senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity" EXACT [EC:1.14.13.101] synonym: "SNO" RELATED [EC:1.14.13.101] xref: EC:1.14.13.101 xref: GO:0033784 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005273 name: heptose 7-phosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP." [MetaCyc:RXN0-4341] subset: gosubset_prok synonym: "D-alpha,beta-D-heptose 7-phosphate 1-kinase activity" EXACT [] xref: EC:2.7.1.- xref: GO:0033785 xref: IMG:02784 xref: MetaCyc:RXN0-4341 is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0005274 name: heptose 1-phosphate adenyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose." [MetaCyc:RXN0-4342] subset: gosubset_prok synonym: "D-beta-D-heptose 1-phosphate adenylyltransferase activity" EXACT [] xref: GO:0033786 xref: IMG:02786 xref: MetaCyc:RXN0-4342 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0005275 name: cyanocobalamin reductase (cyanide-eliminating) activity namespace: molecular_function def: "Catalysis of the reaction: cob(I)alamin + cyanide + NADP+ = cyanocob(III)alamin + NADPH + H+." [EC:1.16.1.6] synonym: "cob(I)alamin, cyanide:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.6] synonym: "cyanocobalamin reductase (NADPH, cyanide-eliminating) activity" EXACT [EC:1.16.1.6] synonym: "cyanocobalamin reductase (NADPH; CN-eliminating) activity" EXACT [EC:1.16.1.6] synonym: "cyanocobalamin reductase activity" EXACT [EC:1.16.1.6] synonym: "NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity" EXACT [EC:1.16.1.6] synonym: "NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity" EXACT [EC:1.16.1.6] xref: EC:1.16.1.6 xref: GO:0033787 is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0005276 name: leucoanthocyanidin reductase activity namespace: molecular_function def: "Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+." [EC:1.17.1.3] synonym: "(2R,3S)-catechin:NADP+ 4-oxidoreductase activity" EXACT [EC:1.17.1.3] synonym: "leucocyanidin reductase activity" EXACT [EC:1.17.1.3] xref: EC:1.17.1.3 xref: GO:0033788 is_a: CCO:F0003308 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [Term] id: CCO:F0005277 name: phenylacetyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: phenylacetyl-CoA + H2O + 2 quinone = phenylglyoxylyl-CoA + 2 quinol." [EC:1.17.5.1] synonym: "phenylacetyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.17.5.1] synonym: "phenylacetyl-CoA:quinone oxidoreductase activity" EXACT [EC:1.17.5.1] xref: EC:1.17.5.1 xref: GO:0033789 is_a: CCO:F0005197 ! oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor [Term] id: CCO:F0005278 name: hydroxymethylfurfural reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391] xref: GO:0033790 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005279 name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor." [EC:1.17.99.3] synonym: "(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity" EXACT [EC:1.17.99.3] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity" EXACT [EC:1.17.99.3] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity" EXACT [EC:1.17.99.3] synonym: "THC-CoA oxidase activity" EXACT [EC:1.17.99.3] synonym: "THCA-CoA oxidase activity" EXACT [EC:1.17.99.3] synonym: "trihydroxycoprostanoyl-CoA oxidase activity" EXACT [EC:1.17.99.3] xref: EC:1.17.99.3 xref: GO:0033791 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0005280 name: bile-acid 7alpha-dehydroxylase activity namespace: molecular_function def: "Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2 and lithocholate + FAD + H2O = chenodeoxycholate + FADH2." [EC:1.17.99.5] synonym: "7alpha-dehydroxylase activity" EXACT [EC:1.17.99.5] synonym: "bile acid 7-dehydroxylase activity" EXACT [EC:1.17.99.5] synonym: "cholate 7alpha-dehydroxylase activity" EXACT [EC:1.17.99.5] synonym: "deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating) activity" EXACT [EC:1.17.99.5] synonym: "deoxycholate:NAD+ oxidoreductase activity" EXACT [EC:1.17.99.5] xref: EC:1.17.99.5 xref: GO:0033792 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0005281 name: aureusidin synthase activity namespace: molecular_function def: "Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O." [EC:1.21.3.6] synonym: "2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity" EXACT [EC:1.21.3.6] xref: EC:1.21.3.6 xref: GO:0033793 is_a: CCO:F0006307 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor [Term] id: CCO:F0005282 name: sarcosine reductase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin." [EC:1.21.4.3] synonym: "acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming) activity" EXACT [EC:1.21.4.3] xref: EC:1.21.4.3 xref: GO:0033794 is_a: CCO:F0007826 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor [Term] id: CCO:F0005283 name: betaine reductase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin." [EC:1.21.4.4] synonym: "acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity" EXACT [EC:1.21.4.4] xref: EC:1.21.4.4 xref: GO:0033795 is_a: CCO:F0007826 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor [Term] id: CCO:F0005284 name: sulfur reductase activity namespace: molecular_function def: "Catalysis of the reaction: reduction of elemental sulfur or polysulfide to hydrogen sulfide." [EC:1.97.1.3] synonym: "(donor):sulfur oxidoreductase activity" EXACT [EC:1.97.1.3] synonym: "sulphur reductase activity" EXACT [] xref: EC:1.97.1.3 xref: GO:0033796 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0005285 name: selenate reductase activity namespace: molecular_function def: "Catalysis of the reaction: selenite + H2O + acceptor = selenate + reduced acceptor." [EC:1.97.1.9] synonym: "selenite:reduced acceptor oxidoreductase activity" EXACT [EC:1.97.1.9] xref: EC:1.97.1.9 xref: GO:0033797 xref: UM-BBD_enzymeID:e0508 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0005286 name: thyroxine 5-deiodinase activity namespace: molecular_function def: "Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2." [EC:1.97.1.11] synonym: "acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity" EXACT [EC:1.97.1.11] synonym: "diiodothyronine 5'-deiodinase activity" BROAD [EC:1.97.1.11] synonym: "iodothyronine 5-deiodinase activity" EXACT [EC:1.97.1.11] synonym: "iodothyronine inner ring monodeiodinase activity" EXACT [EC:1.97.1.11] synonym: "type III iodothyronine deiodinase activity" NARROW [EC:1.97.1.11] xref: EC:1.97.1.11 xref: GO:0033798 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0005287 name: myricetin O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + myricetin = 2 S-adenosyl-L-homocysteine + syringetin." [EC:2.1.1.149] synonym: "CrCOMT2" RELATED [EC:2.1.1.149] synonym: "flavonoid 3',5'-O-dimethyltransferase activity" EXACT [EC:2.1.1.149] synonym: "S-adenosyl-L-methionine:myricetin O-methyltransferase activity" EXACT [EC:2.1.1.149] xref: EC:2.1.1.149 xref: GO:0033799 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005288 name: isoflavone 7-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone." [EC:2.1.1.150] synonym: "S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity" EXACT [EC:2.1.1.150] xref: EC:2.1.1.150 xref: GO:0033800 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005289 name: vitexin 2''-O-rhamnoside 7-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside." [EC:2.1.1.153] synonym: "S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity" EXACT [EC:2.1.1.153] xref: EC:2.1.1.153 xref: GO:0033801 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005290 name: isoliquiritigenin 2'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin." [EC:2.1.1.154] synonym: "chalcone OMT" RELATED [EC:2.1.1.154] synonym: "CHMT" RELATED [EC:2.1.1.154] synonym: "S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase activity" EXACT [EC:2.1.1.154] xref: EC:2.1.1.154 xref: GO:0033802 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005291 name: kaempferol 4'-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + kaempferide." [EC:2.1.1.155] synonym: "F 4'-OMT" RELATED [EC:2.1.1.155] synonym: "S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase activity" EXACT [EC:2.1.1.155] synonym: "S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase activity" EXACT [EC:2.1.1.155] xref: EC:2.1.1.155 xref: GO:0033803 is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005292 name: glycine/sarcosine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine." [EC:2.1.1.156] synonym: "ApGSMT" RELATED [EC:2.1.1.156] synonym: "glycine sarcosine N-methyltransferase activity" EXACT [EC:2.1.1.156] synonym: "glycine-sarcosine methyltransferase activity" EXACT [EC:2.1.1.156] synonym: "GMT" RELATED [EC:2.1.1.156] synonym: "GSMT" RELATED [EC:2.1.1.156] synonym: "S-adenosyl-L-methionine:sarcosine N-methyltransferase activity" EXACT [EC:2.1.1.156] xref: EC:2.1.1.156 xref: GO:0033804 is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005293 name: sarcosine/dimethylglycine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reactions: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine and S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine." [EC:2.1.1.157] synonym: "ApDMT" RELATED [EC:2.1.1.157] synonym: "S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity" EXACT [EC:2.1.1.157] synonym: "sarcosine dimethylglycine N-methyltransferase activity" EXACT [EC:2.1.1.157] synonym: "sarcosine-dimethylglycine methyltransferase activity" EXACT [EC:2.1.1.157] synonym: "SDMT" RELATED [EC:2.1.1.157] xref: EC:2.1.1.157 xref: GO:0033805 is_a: CCO:F0001757 ! N-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005294 name: fluorothreonine transaldolase activity namespace: molecular_function def: "Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine." [EC:2.2.1.8] synonym: "fluoroacetaldehyde:L-threonine aldehydetransferase activity" EXACT [EC:2.2.1.8] xref: EC:2.2.1.8 xref: GO:0033806 is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0005295 name: icosanoyl-CoA synthase activity namespace: molecular_function def: "Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+." [EC:2.3.1.119] synonym: "acyl-CoA elongase activity" EXACT [EC:2.3.1.119] synonym: "C18-CoA elongase activity" EXACT [EC:2.3.1.119] synonym: "stearoyl-CoA elongase activity" EXACT [EC:2.3.1.119] synonym: "stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) activity" EXACT [EC:2.3.1.119] xref: EC:2.3.1.119 xref: GO:0033807 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005296 name: 6'-deoxychalcone synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O." [EC:2.3.1.170] synonym: "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing) activity" EXACT [EC:2.3.1.170] xref: EC:2.3.1.170 xref: GO:0033808 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005297 name: anthocyanin 6''-O-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside)." [EC:2.3.1.171] synonym: "3MaT" RELATED [EC:2.3.1.171] synonym: "Dv3MaT" RELATED [EC:2.3.1.171] synonym: "malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.171] synonym: "malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.171] xref: EC:2.3.1.171 xref: GO:0033809 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005298 name: anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin." [EC:2.3.1.172] synonym: "malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase activity" EXACT [EC:2.3.1.172] synonym: "Ss5MaT1" RELATED [EC:2.3.1.172] xref: EC:2.3.1.172 xref: GO:0033810 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005299 name: flavonol-3-O-triglucoside O-coumaroyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]." [EC:2.3.1.173] synonym: "4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase activity" EXACT [EC:2.3.1.173] xref: EC:2.3.1.173 xref: GO:0033811 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005300 name: 3-oxoadipyl-CoA thiolase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA." [EC:2.3.1.174] synonym: "succinyl-CoA:acetyl-CoA C-succinyltransferase activity" EXACT [EC:2.3.1.174] xref: EC:2.3.1.174 xref: GO:0033812 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005301 name: deacetylcephalosporin-C acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = CoA + cephalosporin C." [EC:2.3.1.175] synonym: "acetyl coenzyme A:DAC acetyltransferase activity" EXACT [EC:2.3.1.175] synonym: "acetyl-CoA:DAC acetyltransferase activity" EXACT [EC:2.3.1.175] synonym: "acetyl-CoA:DAC O-acetyltransferase activity" EXACT [EC:2.3.1.175] synonym: "acetyl-CoA:deacetylcephalosporin-C acetyltransferase activity" EXACT [EC:2.3.1.175] synonym: "acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase activity" EXACT [EC:2.3.1.175] synonym: "cefG" RELATED [EC:2.3.1.175] synonym: "CPC acetylhydrolase activity" EXACT [EC:2.3.1.175] synonym: "DAC acetyltransferase activity" EXACT [EC:2.3.1.175] synonym: "DAC-AT" RELATED [EC:2.3.1.175] synonym: "deacetylcephalosporin C acetyltransferase activity" EXACT [EC:2.3.1.175] xref: EC:2.3.1.175 xref: GO:0033813 is_a: CCO:F0003131 ! C-acyltransferase activity [Term] id: CCO:F0005302 name: propanoyl-CoA C-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA." [EC:2.3.1.176] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity" EXACT [EC:2.3.1.176] synonym: "peroxisomal thiolase 2 activity" NARROW [EC:2.3.1.176] synonym: "PTE-2" RELATED [EC:2.3.1.176] synonym: "SCP-X" RELATED [EC:2.3.1.176] synonym: "SCPchi" RELATED [EC:2.3.1.176] synonym: "sterol carrier protein-chi" RELATED [EC:2.3.1.176] synonym: "sterol carrier protein-X" RELATED [EC:2.3.1.176] xref: EC:2.3.1.176 xref: GO:0033814 is_a: CCO:F0003131 ! C-acyltransferase activity [Term] id: CCO:F0005303 name: biphenyl synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2." [EC:2.3.1.177] synonym: "BIS" RELATED [EC:2.3.1.177] synonym: "malonyl-CoA:benzoyl-CoA malonyltransferase activity" EXACT [EC:2.3.1.177] xref: EC:2.3.1.177 xref: GO:0033815 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005304 name: diaminobutyrate acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-2,4-diaminobutanoate = CoA + N4-acetyl-L-2,4-diaminobutanoate." [EC:2.3.1.178] synonym: "2,4-diaminobutanoate acetyltransferase activity" EXACT [EC:2.3.1.178] synonym: "acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase activity" EXACT [EC:2.3.1.178] synonym: "acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase activity" EXACT [EC:2.3.1.178] synonym: "DAB acetyltransferase activity" EXACT [EC:2.3.1.178] synonym: "DABA acetyltransferase activity" EXACT [EC:2.3.1.178] synonym: "DABAcT" RELATED [EC:2.3.1.178] synonym: "diaminobutyric acid acetyltransferase activity" EXACT [EC:2.3.1.178] synonym: "EctA" RELATED [EC:2.3.1.178] synonym: "L-2,4-diaminobutanoate acetyltransferase activity" EXACT [EC:2.3.1.178] synonym: "L-2,4-diaminobutyrate acetyltransferase activity" EXACT [EC:2.3.1.178] xref: EC:2.3.1.178 xref: GO:0033816 is_a: CCO:F0003130 ! acetyltransferase activity [Term] id: CCO:F0005305 name: beta-ketoacyl-acyl-carrier-protein synthase II activity namespace: molecular_function def: "Catalysis of the reaction: (Z)-hexadec-11-enoyl-acyl-carrier-protein + malonyl-acyl-carrier-protein = (Z)-3-oxooctadec-13-enoyl-acyl-carrier-protein + CO2 + acyl-carrier-protein." [EC:2.3.1.179] synonym: "(Z)-hexadec-11-enoyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating) activity" EXACT [EC:2.3.1.179] synonym: "3-oxoacyl-acyl carrier protein synthase I activity" EXACT [EC:2.3.1.179] synonym: "beta-ketoacyl-ACP synthase II activity" EXACT [EC:2.3.1.179] synonym: "FabF" RELATED [EC:2.3.1.179] synonym: "KAS II" RELATED [EC:2.3.1.179] synonym: "KASII" RELATED [EC:2.3.1.179] xref: EC:2.3.1.179 xref: GO:0033817 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005306 name: beta-ketoacyl-acyl-carrier-protein synthase III activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + malonyl-acyl-carrier-protein = acetoacyl-acyl-carrier-protein + CoA + CO2." [EC:2.3.1.180] synonym: "3-ketoacyl-acyl carrier protein synthase III activity" EXACT [EC:2.3.1.180] synonym: "3-oxoacyl:ACP synthase III activity" EXACT [EC:2.3.1.180] synonym: "acetyl-CoA:malonyl-acyl-carrier-protein C-acyltransferase activity" EXACT [EC:2.3.1.180] synonym: "beta-ketoacyl (acyl carrier protein) synthase III activity" EXACT [EC:2.3.1.180] synonym: "beta-ketoacyl-ACP synthase III activity" EXACT [EC:2.3.1.180] synonym: "beta-ketoacyl-acyl carrier protein synthase III activity" EXACT [EC:2.3.1.180] synonym: "FabH" RELATED [EC:2.3.1.180] synonym: "KAS III" RELATED [EC:2.3.1.180] synonym: "KASIII" RELATED [EC:2.3.1.180] xref: EC:2.3.1.180 xref: GO:0033818 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005307 name: lipoyl(octanoyl) transferase activity namespace: molecular_function def: "Catalysis of the reaction: octanoyl-acyl-carrier-protein + protein = protein N6-(octanoyl)lysine + acyl carrier protein." [EC:2.3.1.181] synonym: "LipB" RELATED [EC:2.3.1.181] synonym: "lipoate/octanoate transferase activity" EXACT [EC:2.3.1.181] synonym: "lipoyl (octanoyl)-acyl carrier protein:protein transferase activity" EXACT [EC:2.3.1.181] synonym: "lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity" EXACT [EC:2.3.1.181] synonym: "octanoyl-acyl carrier protein-protein N-octanoyltransferase activity" EXACT [EC:2.3.1.181] synonym: "octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity" EXACT [EC:2.3.1.181] synonym: "octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity" EXACT [EC:2.3.1.181] xref: EC:2.3.1.181 xref: GO:0033819 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005308 name: DNA alpha-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers an alpha-D-glucosyl residue from UDP-glucose to an hydroxymethylcytosine residue in DNA." [EC:2.4.1.26] synonym: "T2-HMC-alpha-glucosyl transferase activity" EXACT [EC:2.4.1.26] synonym: "T4-HMC-alpha-glucosyl transferase activity" EXACT [EC:2.4.1.26] synonym: "T6-HMC-alpha-glucosyl transferase activity" EXACT [EC:2.4.1.26] synonym: "UDP-glucose:DNA alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.26] synonym: "UDPglucose-DNA alpha-glucosyltransferase activity" EXACT [EC:2.4.1.26] synonym: "uridine diphosphoglucose-deoxyribonucleate alpha-glucosyltransferase activity" EXACT [EC:2.4.1.26] xref: EC:2.4.1.26 xref: GO:0033820 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005309 name: DNA beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers a beta-D-glucosyl residue from UDP-glucose to an hydroxymethylcytosine residue in DNA." [EC:2.4.1.27] synonym: "T4 phage beta-glucosyltransferase activity" EXACT [EC:2.4.1.27] synonym: "T4-beta-glucosyl transferase activity" EXACT [EC:2.4.1.27] synonym: "T4-HMC-beta-glucosyl transferase activity" EXACT [EC:2.4.1.27] synonym: "UDP glucose-DNA beta-glucosyltransferase activity" EXACT [EC:2.4.1.27] synonym: "UDP-glucose:DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.27] synonym: "UDPglucose:DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.27] synonym: "uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase activity" EXACT [EC:2.4.1.27] xref: EC:2.4.1.27 xref: GO:0033821 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005310 name: glucosyl-DNA beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA." [EC:2.4.1.28] synonym: "T6-beta-glucosyl transferase activity" EXACT [EC:2.4.1.28] synonym: "T6-glucosyl-HMC-beta-glucosyl transferase activity" EXACT [EC:2.4.1.28] synonym: "UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.28] synonym: "UDPglucose:D-glucosyl-DNA beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.28] synonym: "uridine diphosphoglucose-glucosyldeoxyribonucleate beta-glucosyltransferase activity" EXACT [EC:2.4.1.28] xref: EC:2.4.1.28 xref: GO:0033822 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005311 name: procollagen glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen." [EC:2.4.1.66] synonym: "collagen glucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "collagen hydroxylysyl glucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "galactosylhydroxylysine glucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "galactosylhydroxylysine-glucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "galactosylhydroxylysyl glucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "UDP-glucose-collagenglucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity" EXACT [EC:2.4.1.66] synonym: "uridine diphosphoglucose-collagen glucosyltransferase activity" EXACT [EC:2.4.1.66] xref: EC:2.4.1.66 xref: GO:0033823 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005312 name: alternansucrase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers alternately an alpha-D-glucosyl residue from sucrose to the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages." [EC:2.4.1.140] synonym: "sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase activity" EXACT [EC:2.4.1.140] synonym: "sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.140] synonym: "sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase activity" BROAD [EC:2.4.1.140] xref: EC:2.4.1.140 xref: GO:0033824 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005313 name: oligosaccharide 4-alpha-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides." [EC:2.4.1.161] synonym: "1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.161] synonym: "1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glucosyltransferase activity" EXACT [EC:2.4.1.161] synonym: "amylase III activity" EXACT [EC:2.4.1.161] xref: EC:2.4.1.161 xref: GO:0033825 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005314 name: xyloglucan 4-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage." [EC:2.4.1.168] synonym: "UDP-glucose:xyloglucan 1,4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.168] synonym: "UDPglucose:xyloglucan 1,4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.168] synonym: "uridine diphosphoglucose-xyloglucan 4beta-glucosyltransferase activity" EXACT [EC:2.4.1.168] synonym: "xyloglucan 4beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.168] synonym: "xyloglucan glucosyltransferase activity" EXACT [EC:2.4.1.168] xref: EC:2.4.1.168 xref: GO:0033826 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005315 name: high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum." [EC:2.4.1.197] synonym: "acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] synonym: "UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] synonym: "UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] synonym: "uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.197] xref: EC:2.4.1.197 xref: GO:0033827 is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0005316 name: glucosylglycerol-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: ADP-glucose + sn-glycerol 3-phosphate = 2-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP." [EC:2.4.1.213] synonym: "ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.213] synonym: "ADPglucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.213] synonym: "GG-phosphate synthase activity" EXACT [EC:2.4.1.213] synonym: "GGPS" RELATED [EC:2.4.1.213] synonym: "glucosyl-glycerol-phosphate synthase activity" EXACT [EC:2.4.1.213] xref: EC:2.4.1.213 xref: GO:0033828 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005317 name: O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor." [EC:2.4.1.222] synonym: "O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.222] synonym: "UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.222] xref: EC:2.4.1.222 xref: GO:0033829 is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0005318 name: Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline." [EC:2.4.1.229] synonym: "Skp1-HyPro GlcNAc-transferase activity" EXACT [EC:2.4.1.229] synonym: "UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity" EXACT [EC:2.4.1.229] synonym: "UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase activity" EXACT [EC:2.4.1.229] synonym: "UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity" EXACT [EC:2.4.1.229] synonym: "UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity" EXACT [EC:2.4.1.229] xref: EC:2.4.1.229 xref: GO:0033830 is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0005319 name: kojibiose phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-alpha-D-glucosyl-D-glucose + phosphate = D-glucose + beta-D-glucose 1-phosphate." [EC:2.4.1.230] synonym: "2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.230] xref: EC:2.4.1.230 xref: GO:0033831 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005320 name: alpha,alpha-trehalose phosphorylase (configuration-retaining) activity namespace: molecular_function def: "Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate." [EC:2.4.1.231] synonym: "alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.231] synonym: "trehalose phosphorylase activity" BROAD [EC:2.4.1.231] xref: GO:0033832 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005321 name: hydroxymethylfurfural reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391] xref: GO:0033833 is_a: CCO:F0005278 ! hydroxymethylfurfural reductase activity [Term] id: CCO:F0005322 name: kaempferol 3-O-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside." [EC:2.4.1.234] synonym: "F3GalTase activity" EXACT [EC:2.4.1.234] synonym: "UDP-galactose:kaempferol 3-O-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.234] xref: EC:2.4.1.234 xref: GO:0033834 is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0005323 name: flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside]." [EC:2.4.1.236] synonym: "1->2 UDP-rhamnosyltransferase activity" EXACT [EC:2.4.1.236] synonym: "UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity" EXACT [EC:2.4.1.236] synonym: "UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity" EXACT [EC:2.4.1.236] xref: EC:2.4.1.236 xref: GO:0033835 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0005324 name: flavonol 7-O-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside." [EC:2.4.1.237] synonym: "UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.237] synonym: "UDP-glucose:flavonol 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.237] xref: EC:2.4.1.237 xref: GO:0033836 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005325 name: anthocyanin 3'-O-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside." [EC:2.4.1.238] synonym: "3'GT" RELATED [EC:2.4.1.238] synonym: "UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.238] synonym: "UDP-glucose:anthocyanin 3'-O-glucosyltransferase activity" EXACT [EC:2.4.1.238] xref: EC:2.4.1.238 xref: GO:0033837 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005326 name: flavonol-3-O-glucoside glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside." [EC:2.4.1.239] synonym: "UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.239] xref: EC:2.4.1.239 xref: GO:0033838 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005327 name: flavonol-3-O-glycoside glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside." [EC:2.4.1.240] synonym: "UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.240] xref: EC:2.4.1.240 xref: GO:0033839 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005328 name: NDP-glucose-starch glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1." [EC:2.4.1.242] synonym: "GBSS" RELATED [EC:2.4.1.242] synonym: "GBSSI" RELATED [EC:2.4.1.242] synonym: "GBSSII" RELATED [EC:2.4.1.242] synonym: "granule-bound starch synthase activity" EXACT [EC:2.4.1.242] synonym: "granule-bound starch synthase I activity" EXACT [EC:2.4.1.242] synonym: "granule-bound starch synthase II activity" EXACT [EC:2.4.1.242] synonym: "NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.242] synonym: "NDPglucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.242] synonym: "starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase activity" EXACT [EC:2.4.1.242] synonym: "starch synthase II activity" EXACT [EC:2.4.1.242] synonym: "waxy protein" RELATED [EC:2.4.1.242] xref: EC:2.4.1.242 xref: GO:0033840 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005329 name: 6G-fructosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0)." [EC:2.4.1.243] synonym: "1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase activity" EXACT [EC:2.4.1.243] synonym: "6G-FFT" RELATED [EC:2.4.1.243] synonym: "6G-fructotransferase activity" EXACT [EC:2.4.1.243] synonym: "6G-FT" RELATED [EC:2.4.1.243] synonym: "fructan:fructan 6G-fructosyltransferase activity" EXACT [EC:2.4.1.243] xref: EC:2.4.1.243 xref: GO:0033841 is_a: CCO:F0008006 ! fructosyltransferase activity [Term] id: CCO:F0005330 name: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group." [EC:2.4.1.244] synonym: "beta1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.244] synonym: "beta1,4-N-acetylgalactosaminyltransferase III activity" EXACT [EC:2.4.1.244] synonym: "beta1,4-N-acetylgalactosaminyltransferase IV activity" EXACT [EC:2.4.1.244] synonym: "beta4GalNAc-T3" RELATED [EC:2.4.1.244] synonym: "beta4GalNAc-T4" RELATED [EC:2.4.1.244] synonym: "UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.244] xref: EC:2.4.1.244 xref: GO:0033842 is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0005331 name: xyloglucan 6-xylosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Transfers an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage." [EC:2.4.2.39] synonym: "UDP-D-xylose:xyloglucan 1,6-alpha-D-xylosyltransferase activity" EXACT [EC:2.4.2.39] synonym: "uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity" EXACT [EC:2.4.2.39] synonym: "xyloglucan 6-alpha-D-xylosyltransferase activity" EXACT [EC:2.4.2.39] xref: EC:2.4.2.39 xref: GO:0033843 is_a: CCO:F0005645 ! xylosyltransferase activity [Term] id: CCO:F0005332 name: galactose-6-sulfurylase activity namespace: molecular_function def: "Catalysis of the reaction: Eliminates sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues." [EC:2.5.1.5] synonym: "D-galactose-6-sulfate:alkyltransferase (cyclizing) activity" EXACT [EC:2.5.1.5] synonym: "galactose 6-sulfatase activity" EXACT [EC:2.5.1.5] synonym: "galactose-6-sulfatase activity" EXACT [EC:2.5.1.5] synonym: "porphyran sulfatase activity" EXACT [EC:2.5.1.5] xref: EC:2.5.1.5 xref: GO:0033844 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005333 name: hydroxymethylfurfural reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+." [GOC:jp, GOC:mah, PMID:15338422, PMID:16652391] xref: GO:0033845 is_a: CCO:F0005278 ! hydroxymethylfurfural reductase activity [Term] id: CCO:F0005334 name: adenosyl-fluoride synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine." [EC:2.5.1.63] synonym: "fluorinase activity" EXACT [EC:2.5.1.63] synonym: "S-adenosyl-L-methionine:fluoride adenosyltransferase activity" EXACT [EC:2.5.1.63] xref: EC:2.5.1.63 xref: GO:0033846 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005335 name: O-phosphoserine sulfhydrylase activity namespace: molecular_function def: "Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate." [EC:2.5.1.65] synonym: "O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.65] synonym: "O-phosphoserine(thiol)-lyase activity" EXACT [EC:2.5.1.65] xref: EC:2.5.1.65 xref: GO:0033847 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005336 name: N2-(2-carboxyethyl)arginine synthase activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N2-(2-carboxyethyl)-L-arginine + phosphate." [EC:2.5.1.66] synonym: "CEA synthetase activity" EXACT [EC:2.5.1.66] synonym: "CEAS" RELATED [EC:2.5.1.66] synonym: "glyceraldehyde-3-phosphate:L-arginine 2-N-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity" EXACT [EC:2.5.1.66] synonym: "glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity" EXACT [EC:2.5.1.66] synonym: "N2-(2-carboxyethyl)arginine synthetase activity" EXACT [EC:2.5.1.66] xref: EC:2.5.1.66 xref: GO:0033848 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005337 name: chrysanthemyl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + chrysanthemyl diphosphate." [EC:2.5.1.67] synonym: "CPPase activity" EXACT [EC:2.5.1.67] synonym: "dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming) activity" EXACT [EC:2.5.1.67] xref: EC:2.5.1.67 xref: GO:0033849 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005338 name: Z-farnesyl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2Z,6E)-farnesyl diphosphate." [EC:2.5.1.68] synonym: "(Z)-farnesyl diphosphate synthase activity" EXACT [EC:2.5.1.68] synonym: "geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase activity" EXACT [EC:2.5.1.68] xref: EC:2.5.1.68 xref: GO:0033850 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005339 name: lavandulyl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate." [EC:2.5.1.69] synonym: "dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming) activity" EXACT [EC:2.5.1.69] synonym: "FDS-5" RELATED [EC:2.5.1.69] xref: EC:2.5.1.69 xref: GO:0033851 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005340 name: thyroid-hormone transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-3,5,3'-triiodothyronine + 2-oxoglutarate = 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-2-oxopropanoate + L-glutamate." [EC:2.6.1.26] synonym: "3,5-dinitrotyrosine aminotransferase activity" EXACT [EC:2.6.1.26] synonym: "3,5-dinitrotyrosine transaminase activity" EXACT [EC:2.6.1.26] synonym: "L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.26] synonym: "thyroid hormone aminotransferase activity" EXACT [EC:2.6.1.26] synonym: "thyroid-hormone aminotransferase activity" EXACT [EC:2.6.1.26] xref: EC:2.6.1.26 xref: GO:0033852 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005341 name: aspartate-prephenate aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate." [EC:2.6.1.78] synonym: "L-arogenate:oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.78] synonym: "L-aspartate:prephenate aminotransferase activity" EXACT [EC:2.6.1.78] synonym: "PAT" RELATED [EC:2.6.1.78] synonym: "prephenate aspartate aminotransferase activity" EXACT [EC:2.6.1.78] synonym: "prephenate transaminase activity" BROAD [EC:2.6.1.78] xref: EC:2.6.1.78 xref: GO:0033853 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005342 name: glutamate-prephenate aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-arogenate + 2-oxoglutarate = prephenate + L-glutamate." [EC:2.6.1.79] synonym: "L-arogenate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.79] synonym: "L-glutamate:prephenate aminotransferase activity" EXACT [EC:2.6.1.79] synonym: "PAT" RELATED [EC:2.6.1.79] synonym: "prephenate transaminase activity" BROAD [EC:2.6.1.79] xref: EC:2.6.1.79 xref: GO:0033854 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005343 name: nicotianamine aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: nicotianamine + 2-oxoglutarate = 3''-deamino-3''-oxonicotianamine + L-glutamate." [EC:2.6.1.80] synonym: "NAAT" RELATED [EC:2.6.1.80] synonym: "NAAT-I" RELATED [EC:2.6.1.80] synonym: "NAAT-II" RELATED [EC:2.6.1.80] synonym: "NAAT-III" RELATED [EC:2.6.1.80] synonym: "nicotianamine transaminase activity" EXACT [EC:2.6.1.80] synonym: "nicotianamine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.80] xref: EC:2.6.1.80 xref: GO:0033855 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005344 name: pyridoxine 5'-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = pyridoxine 5'-phosphate + phosphate + 2 H2O." [EC:2.6.99.2] synonym: "1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing) activity" EXACT [EC:2.6.99.2] synonym: "PdxJ" RELATED [EC:2.6.99.2] synonym: "PNP synthase activity" EXACT [EC:2.6.99.2] synonym: "pyridoxine 5-phosphate phospho lyase activity" EXACT [EC:2.6.99.2] xref: EC:2.6.99.2 xref: GO:0033856 is_a: CCO:F0003342 ! transferase activity, transferring nitrogenous groups [Term] id: CCO:F0005345 name: diphosphoinositol-pentakisphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown)." [EC:2.7.4.24] synonym: "ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase activity" EXACT [EC:2.7.4.24] synonym: "PP-InsP5 kinase activity" EXACT [EC:2.7.4.24] synonym: "PP-IP5 kinase activity" EXACT [EC:2.7.4.24] synonym: "PPIP5K" RELATED [EC:2.7.4.24] synonym: "PPIP5K1" RELATED [EC:2.7.4.24] synonym: "PPIP5K2" RELATED [EC:2.7.4.24] synonym: "VIP1" NARROW [EC:2.7.4.24] synonym: "VIP2" NARROW [EC:2.7.4.24] xref: EC:2.7.4.24 xref: GO:0033857 is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0005346 name: N-acetylgalactosamine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate." [EC:2.7.1.157] synonym: "ATP:N-acetyl-D-galactosamine 1-phosphotransferase activity" EXACT [EC:2.7.1.157] synonym: "GALK2" RELATED [EC:2.7.1.157] synonym: "GalNAc kinase activity" EXACT [EC:2.7.1.157] synonym: "GK2" RELATED [EC:2.7.1.157] synonym: "N-acetylgalactosamine (GalNAc)-1-phosphate kinase activity" EXACT [EC:2.7.1.157] xref: EC:2.7.1.157 xref: GO:0033858 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0005347 name: UMP kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + UMP = ADP + UDP." [EC:2.7.4.22] synonym: "ATP:UMP phosphotransferase activity" EXACT [EC:2.7.4.22] synonym: "PyrH" RELATED [EC:2.7.4.22] synonym: "SmbA" RELATED [EC:2.7.4.22] synonym: "UMP-kinase activity" EXACT [EC:2.7.4.22] synonym: "UMPK" RELATED [EC:2.7.4.22] synonym: "uridine monophosphate kinase activity" EXACT [EC:2.7.4.22] xref: EC:2.7.4.22 xref: GO:0033862 is_a: CCO:F0002370 ! uridylate kinase activity [Term] id: CCO:F0005348 name: ribose 1,5-bisphosphate phosphokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate." [EC:2.7.4.23] synonym: "ATP:ribose-1,5-bisphosphate phosphotransferase activity" EXACT [EC:2.7.4.23] synonym: "PhnN" RELATED [EC:2.7.4.23] synonym: "ribose 1,5-bisphosphokinase activity" EXACT [EC:2.7.4.23] xref: EC:2.7.4.23 xref: GO:0033863 is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0005349 name: Fas-activated serine/threonine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein." [EC:2.7.11.8] synonym: "ATP:Fas-activated serine/threonine protein phosphotransferase activity" EXACT [EC:2.7.11.8] synonym: "FAST" RELATED [EC:2.7.11.8] synonym: "FASTK" RELATED [EC:2.7.11.8] synonym: "STK10" RELATED [EC:2.7.11.8] xref: EC:2.7.11.8 xref: GO:0033867 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0005350 name: Goodpasture-antigen-binding protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein." [EC:2.7.11.9] synonym: "ATP:Goodpasture antigen-binding protein phosphotransferase activity" EXACT [EC:2.7.11.9] synonym: "Goodpasture antigen-binding protein kinase activity" EXACT [EC:2.7.11.9] synonym: "GPBP kinase activity" EXACT [EC:2.7.11.9] synonym: "GPBPK" RELATED [EC:2.7.11.9] synonym: "STK11" RELATED [EC:2.7.11.9] xref: EC:2.7.11.9 xref: GO:0033868 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0005351 name: thiol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate." [EC:2.8.2.16] synonym: "3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity" EXACT [EC:2.8.2.16] synonym: "adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity" EXACT [EC:2.8.2.16] synonym: "PAPS sulfotransferase activity" BROAD [EC:2.8.2.16] xref: EC:2.8.2.16 xref: GO:0033870 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0005354 name: petromyzonol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + 5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol = adenosine 3',5'-bisphosphate + 5alpha-cholan-3alpha,7alpha,12alpha-triol 24-sulfate." [EC:2.8.2.31] synonym: "3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase activity" EXACT [EC:2.8.2.31] synonym: "PZ-SULT" RELATED [EC:2.8.2.31] xref: EC:2.8.2.31 xref: GO:0033873 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0005355 name: scymnol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + 5beta-scymnol = adenosine 3',5'-bisphosphate + 5beta-scymnol sulfate." [EC:2.8.2.32] xref: EC:2.8.2.32 xref: GO:0033874 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0005356 name: glycochenodeoxycholate sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-bisphosphate + glycochenodeoxycholate 7-sulfate." [EC:2.8.2.34] synonym: "3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase activity" EXACT [EC:2.8.2.34] synonym: "BAST" RELATED [EC:2.8.2.34] synonym: "bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity" BROAD [EC:2.8.2.34] synonym: "bile acid:PAPS:sulfotransferase activity" EXACT [EC:2.8.2.34] xref: EC:2.8.2.34 xref: GO:0033876 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0005357 name: succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + (R)-2-benzylsuccinate = succinate + (R)-2-benzylsuccinyl-CoA." [EC:2.8.3.15] synonym: "benzylsuccinate CoA-transferase activity" EXACT [EC:2.8.3.15] synonym: "succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase activity" EXACT [EC:2.8.3.15] xref: EC:2.8.3.15 xref: GO:0033877 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0005358 name: hormone-sensitive lipase activity namespace: molecular_function def: "Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate, triacylglycerol + H2O = diacylglycerol + a carboxylate, and monoacylglycerol + H2O = glycerol + a carboxylate." [EC:3.1.1.79] synonym: "diacylglycerol acylhydrolase activity" EXACT [EC:3.1.1.79] synonym: "HSL" RELATED [EC:3.1.1.79] xref: EC:3.1.1.79 xref: GO:0033878 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0005359 name: acetylajmaline esterase activity namespace: molecular_function def: "Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate and 17-O-acetylnorajmaline + H2O = norajmaline + acetate." [EC:3.1.1.80] synonym: "17-O-acetylajmaline O-acetylhydrolase activity" EXACT [EC:3.1.1.80] synonym: "2beta(R)-17-O-acetylajmalan:acetylesterase activity" EXACT [EC:3.1.1.80] synonym: "AAE" RELATED [EC:3.1.1.80] synonym: "acetylajmalan esterase activity" EXACT [EC:3.1.1.80] xref: EC:3.1.1.80 xref: GO:0033879 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0005360 name: phenylacetyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: phenylglyoxylyl-CoA + H2O = phenylglyoxylate + CoA." [EC:3.1.2.25] synonym: "phenylglyoxylyl-CoA hydrolase activity" EXACT [EC:3.1.2.25] xref: EC:3.1.2.25 xref: GO:0033880 is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0005361 name: bile-acid-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: deoxycholoyl-CoA + H2O = CoA + deoxycholate." [EC:3.1.2.26] synonym: "bile acid-coenzyme A hydrolase activity" EXACT [EC:3.1.2.26] synonym: "deoxycholoyl-CoA hydrolase activity" EXACT [EC:3.1.2.26] xref: EC:3.1.2.26 xref: GO:0033881 is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0005362 name: choloyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA." [EC:3.1.2.27] synonym: "chenodeoxycholoyl-coenzyme A thioesterase activity" EXACT [EC:3.1.2.27] synonym: "choloyl-coenzyme A thioesterase activity" EXACT [EC:3.1.2.27] synonym: "peroxisomal acyl-CoA thioesterase 2 activity" NARROW [EC:3.1.2.27] synonym: "PTE-2" RELATED [EC:3.1.2.27] xref: EC:3.1.2.27 xref: GO:0033882 is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0005363 name: pyridoxal phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate." [EC:3.1.3.74] synonym: "PLP phosphatase activity" EXACT [EC:3.1.3.74] synonym: "PNP phosphatase activity" EXACT [EC:3.1.3.74] synonym: "pyridoxal-5'-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.74] synonym: "vitamin B6-phosphate phosphatase activity" BROAD [EC:3.1.3.74] synonym: "vitamine B6 (pyridoxine) phosphatase activity" BROAD [EC:3.1.3.74] xref: EC:3.1.3.74 xref: GO:0033883 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005364 name: phosphoethanolamine/phosphocholine phosphatase activity namespace: molecular_function def: "Catalysis of the reactions: O-phosphoethanolamine + H2O = ethanolamine + phosphate and phosphocholine + H2O = choline + phosphate." [EC:3.1.3.75] synonym: "3X11A" RELATED [EC:3.1.3.75] synonym: "PHOSPHO1" RELATED [EC:3.1.3.75] synonym: "phosphoethanolamine phosphohydrolase activity" EXACT [EC:3.1.3.75] xref: EC:3.1.3.75 xref: GO:0033884 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005365 name: lipid-phosphate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate." [EC:3.1.3.76] synonym: "(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity" EXACT [EC:3.1.3.76] synonym: "dihydroxy fatty acid phosphatase activity" EXACT [EC:3.1.3.76] synonym: "hydroxy fatty acid phosphatase activity" EXACT [EC:3.1.3.76] synonym: "hydroxy lipid phosphatase activity" EXACT [EC:3.1.3.76] synonym: "sEH" RELATED [EC:3.1.3.76] synonym: "soluble epoxide hydrolase activity" RELATED [EC:3.1.3.76] xref: EC:3.1.3.76 xref: GO:0033885 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005366 name: cellulose-polysulfatase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin." [EC:3.1.6.7] synonym: "cellulose-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.7] xref: EC:3.1.6.7 xref: GO:0033886 is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0005367 name: chondro-4-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + sulfate." [EC:3.1.6.9] synonym: "4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity" EXACT [EC:3.1.6.9] xref: EC:3.1.6.9 xref: GO:0033887 is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0005368 name: chondro-6-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + sulfate." [EC:3.1.6.10] synonym: "4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity" EXACT [EC:3.1.6.10] xref: EC:3.1.6.10 xref: GO:0033888 is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0005369 name: N-sulfoglucosamine-3-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin." [EC:3.1.6.15] synonym: "chondroitinsulfatase activity" BROAD [EC:3.1.6.15] synonym: "N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity" EXACT [EC:3.1.6.15] xref: EC:3.1.6.15 xref: GO:0033889 is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0005370 name: ribonuclease D activity namespace: molecular_function def: "Catalysis of the reaction: exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides." [EC:3.1.13.5] synonym: "RNase D activity" EXACT [EC:3.1.13.5] xref: EC:3.1.13.5 xref: GO:0033890 is_a: CCO:F0003454 ! exoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005371 name: CC-preferring endodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC." [EC:3.1.21.6] synonym: "5'-CC-3'-preferring endodeoxyribonuclease activity" EXACT [EC:3.1.21.6] synonym: "Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease activity" EXACT [EC:3.1.21.6] synonym: "Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease activity" EXACT [EC:3.1.21.6] synonym: "Streptomyces glaucescens exocytoplasmic endonuclease activity" EXACT [EC:3.1.21.6] xref: EC:3.1.21.6 xref: GO:0033891 is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005372 name: deoxyribonuclease (pyrimidine dimer) activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate." [EC:3.1.25.1] synonym: "bacteriophage T4 endodeoxyribonuclease V activity" EXACT [EC:3.1.25.1] synonym: "endodeoxyribonuclease (pyrimidine dimer) activity" EXACT [EC:3.1.25.1] synonym: "T4 endonuclease V activity" EXACT [EC:3.1.25.1] xref: EC:3.1.25.1 xref: GO:0033892 is_a: CCO:F0003448 ! site-specific endodeoxyribonuclease activity, specific for altered base [Term] id: CCO:F0005373 name: ribonuclease IV activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups." [EC:3.1.26.6] synonym: "endoribonuclease IV activity" EXACT [EC:3.1.26.6] xref: EC:3.1.26.6 xref: GO:0033893 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005374 name: ribonuclease P4 activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor." [EC:3.1.26.7] xref: EC:3.1.26.7 xref: GO:0033894 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005375 name: ribonuclease [poly-(U)-specific] activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups." [EC:3.1.26.9] synonym: "ribonuclease (uracil-specific) activity" EXACT [EC:3.1.26.9] synonym: "uracil-specific endoribonuclease activity" EXACT [EC:3.1.26.9] synonym: "uracil-specific RNase activity" EXACT [EC:3.1.26.9] xref: EC:3.1.26.9 xref: GO:0033895 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005376 name: ribonuclease IX activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups." [EC:3.1.26.10] synonym: "poly(U)- and poly(C)-specific endoribonuclease activity" EXACT [EC:3.1.26.10] xref: EC:3.1.26.10 xref: GO:0033896 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005377 name: ribonuclease T2 activity namespace: molecular_function def: "Catalysis of the reaction: two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates." [EC:3.1.27.1] synonym: "acid ribonuclease activity" EXACT [EC:3.1.27.1] synonym: "acid RNase activity" EXACT [EC:3.1.27.1] synonym: "base-non-specific ribonuclease activity" EXACT [EC:3.1.27.1] synonym: "Escherichia coli ribonuclease I' ribonuclease PP2 activity" EXACT [EC:3.1.27.1] synonym: "Escherichia coli ribonuclease II activity" EXACT [EC:3.1.27.1] synonym: "non-base specific ribonuclease activity" EXACT [EC:3.1.27.1] synonym: "nonbase-specific RNase activity" EXACT [EC:3.1.27.1] synonym: "nonspecific RNase activity" EXACT [EC:3.1.27.1] synonym: "ribonnuclease (non-base specific) activity" EXACT [EC:3.1.27.1] synonym: "ribonuclease (non-base specific) activity" EXACT [EC:3.1.27.1] synonym: "ribonuclease II activity" BROAD [EC:3.1.27.1] synonym: "ribonuclease M activity" EXACT [EC:3.1.27.1] synonym: "ribonuclease N2 activity" EXACT [EC:3.1.27.1] synonym: "ribonuclease PP3 activity" EXACT [EC:3.1.27.1] synonym: "ribonuclease U4 activity" EXACT [EC:3.1.27.1] synonym: "ribonucleate 3'-oligonucleotide hydrolase activity" EXACT [EC:3.1.27.1] synonym: "ribonucleate nucleotido-2'-transferase (cyclizing) activity" BROAD [EC:3.1.27.1] synonym: "RNAase CL activity" EXACT [EC:3.1.27.1] synonym: "RNase (non-base specific) activity" EXACT [EC:3.1.27.1] synonym: "RNase II activity" BROAD [EC:3.1.27.1] synonym: "RNase M activity" EXACT [EC:3.1.27.1] synonym: "RNase Ms activity" EXACT [EC:3.1.27.1] synonym: "RNase T2 activity" EXACT [EC:3.1.27.1] xref: EC:3.1.27.1 xref: GO:0033897 is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0005378 name: Bacillus subtilis ribonuclease activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage to 2',3'-cyclic nucleotides." [EC:3.1.27.2] synonym: "proteus mirabilis RNase activity" EXACT [EC:3.1.27.2] synonym: "ribonucleate nucleotido-2'-transferase (cyclizing) activity" BROAD [EC:3.1.27.2] xref: EC:3.1.27.2 xref: GO:0033898 is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0005379 name: ribonuclease U2 activity namespace: molecular_function def: "Catalysis of the reaction: two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates." [EC:3.1.27.4] synonym: "pleospora RNase activity" EXACT [EC:3.1.27.4] synonym: "purine specific endoribonuclease activity" EXACT [EC:3.1.27.4] synonym: "purine-specific ribonuclease activity" EXACT [EC:3.1.27.4] synonym: "purine-specific RNase activity" EXACT [EC:3.1.27.4] synonym: "ribonuclease (purine) activity" EXACT [EC:3.1.27.4] synonym: "ribonuclease U3 activity" EXACT [EC:3.1.27.4] synonym: "RNase U3 activity" EXACT [EC:3.1.27.4] synonym: "trichoderma koningi RNase III activity" EXACT [EC:3.1.27.4] xref: EC:3.1.27.4 xref: GO:0033899 is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0005380 name: ribonuclease F activity namespace: molecular_function def: "Catalysis of the reaction: endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups." [EC:3.1.27.7] synonym: "ribonuclease F (E. coli) activity" EXACT [EC:3.1.27.7] synonym: "RNase F activity" EXACT [EC:3.1.27.7] xref: EC:3.1.27.7 xref: GO:0033900 is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0005381 name: ribonuclease V activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP." [EC:3.1.27.8] synonym: "endoribonuclease V activity" EXACT [EC:3.1.27.8] xref: EC:3.1.27.8 xref: GO:0033901 is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0005382 name: rRNA endonuclease activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes." [EC:3.1.27.10] synonym: "alpha-sarcin" RELATED [EC:3.1.27.10] xref: EC:3.1.27.10 xref: GO:0033902 is_a: CCO:F0003450 ! endoribonuclease activity, producing 3'-phosphomonoesters [Term] id: CCO:F0005383 name: endo-1,3(4)-beta-glucanase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,3- or 1,4-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3." [EC:3.2.1.6] synonym: "1,3-(1,3;1,4)-beta-D-glucan 3(4)-glucanohydrolase activity" EXACT [EC:3.2.1.6] synonym: "beta-1,3-1,4-glucanase activity" EXACT [EC:3.2.1.6] synonym: "beta-1,3-glucanase activity" BROAD [EC:3.2.1.6] synonym: "endo-1,3-1,4-beta-D-glucanase activity" EXACT [EC:3.2.1.6] synonym: "endo-1,3-beta-D-glucanase activity" BROAD [EC:3.2.1.6] synonym: "endo-1,3-beta-glucanase activity" BROAD [EC:3.2.1.6] synonym: "endo-1,4-beta-glucanase activity" BROAD [EC:3.2.1.6] synonym: "endo-beta-(1-3)-D-glucanase activity" BROAD [EC:3.2.1.6] synonym: "endo-beta-(1->3)-D-glucanase activity" BROAD [EC:3.2.1.6] synonym: "endo-beta-1,3(4)-glucanase activity" EXACT [EC:3.2.1.6] synonym: "endo-beta-1,3-1,4-glucanase activity" EXACT [EC:3.2.1.6] synonym: "endo-beta-1,3-glucanase IV activity" EXACT [EC:3.2.1.6] synonym: "laminaranase activity" BROAD [EC:3.2.1.6] synonym: "laminarinase activity" BROAD [EC:3.2.1.6] xref: EC:3.2.1.6 xref: GO:0033903 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005384 name: dextranase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran." [EC:3.2.1.11] synonym: "1,6-alpha-D-glucan 6-glucanohydrolase activity" EXACT [EC:3.2.1.11] synonym: "alpha-1,6-glucan-6-glucanohydrolase activity" EXACT [EC:3.2.1.11] synonym: "alpha-D-1,6-glucan-6-glucanohydrolase activity" EXACT [EC:3.2.1.11] synonym: "dextran hydrolase activity" EXACT [EC:3.2.1.11] synonym: "dextranase DL 2 activity" NARROW [EC:3.2.1.11] synonym: "DL 2" RELATED [EC:3.2.1.11] synonym: "endo-dextranase activity" EXACT [EC:3.2.1.11] synonym: "endodextranase activity" EXACT [EC:3.2.1.11] xref: EC:3.2.1.11 xref: GO:0033904 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005385 name: xylan endo-1,3-beta-xylosidase activity namespace: molecular_function def: "Catalysis of the reaction: random hydrolysis of 1,3-beta-D-glycosidic linkages in 1,3-beta-D-xylans." [EC:3.2.1.32] synonym: "1,3-beta-D-xylan xylanohydrolase activity" EXACT [EC:3.2.1.32] synonym: "1,3-beta-xylanase activity" EXACT [EC:3.2.1.32] synonym: "1,3-xylanase activity" EXACT [EC:3.2.1.32] synonym: "beta-1,3-xylanase activity" EXACT [EC:3.2.1.32] synonym: "endo-1,3-beta-xylanase activity" EXACT [EC:3.2.1.32] synonym: "endo-1,3-xylanase activity" EXACT [EC:3.2.1.32] synonym: "endo-beta-1,3-xylanase activity" EXACT [EC:3.2.1.32] synonym: "xylanase activity" BROAD [EC:3.2.1.32] xref: EC:3.2.1.32 xref: GO:0033905 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005386 name: hyaluronoglucuronidase activity namespace: molecular_function def: "Catalysis of the reaction: random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate." [EC:3.2.1.36] synonym: "glucuronoglucosaminoglycan hyaluronate lyase activity" EXACT [EC:3.2.1.36] synonym: "hyaluronate 3-glycanohydrolase activity" EXACT [EC:3.2.1.36] synonym: "hyaluronidase activity" BROAD [EC:3.2.1.36] synonym: "orgelase activity" EXACT [EC:3.2.1.36] xref: EC:3.2.1.36 xref: GO:0033906 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005387 name: beta-D-fucosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides." [EC:3.2.1.38] synonym: "beta-D-fucoside fucohydrolase activity" EXACT [EC:3.2.1.38] synonym: "beta-fucosidase activity" EXACT [EC:3.2.1.38] xref: EC:3.2.1.38 xref: GO:0033907 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005388 name: beta-L-rhamnosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides." [EC:3.2.1.43] synonym: "beta-L-rhamnoside rhamnohydrolase activity" EXACT [EC:3.2.1.43] xref: EC:3.2.1.43 xref: GO:0033908 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005389 name: fucoidanase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate." [EC:3.2.1.44] synonym: "poly(1,2-alpha-L-fucoside-4-sulfate) glycanohydrolase activity" EXACT [EC:3.2.1.44] xref: EC:3.2.1.44 xref: GO:0033909 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005390 name: glucan 1,4-alpha-maltotetraohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends." [EC:3.2.1.60] synonym: "1,4-alpha-D-glucan maltotetraohydrolase activity" EXACT [EC:3.2.1.60] synonym: "exo-maltotetraohydrolase activity" EXACT [EC:3.2.1.60] synonym: "G4-amylase activity" EXACT [EC:3.2.1.60] synonym: "glucan 1,4-alpha-maltotetrahydrolase activity" EXACT [EC:3.2.1.60] synonym: "maltotetraose-forming amylase activity" EXACT [EC:3.2.1.60] xref: EC:3.2.1.60 xref: GO:0033910 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005391 name: mycodextranase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds." [EC:3.2.1.61] synonym: "1,3-1,4-alpha-D-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.61] xref: EC:3.2.1.61 xref: GO:0033911 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005392 name: 2,6-beta-fructan 6-levanbiohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 2,6-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain." [EC:3.2.1.64] synonym: "2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase activity" EXACT [EC:3.2.1.64] synonym: "2,6-beta-D-fructan 6-levanbiohydrolase activity" EXACT [EC:3.2.1.64] synonym: "2,6-beta-D-fructofuranan 6-(beta-D-fructosyl)-D-fructose-hydrolase activity" EXACT [EC:3.2.1.64] synonym: "beta-2,6-fructan-6-levanbiohydrolase activity" EXACT [EC:3.2.1.64] synonym: "levanbiose-producing levanase activity" EXACT [EC:3.2.1.64] xref: EC:3.2.1.64 xref: GO:0033912 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005393 name: glucan endo-1,2-beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: random hydrolysis of 1,2-glucosidic linkages in 1,2-beta-D-glucans." [EC:3.2.1.71] synonym: "1,2-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.71] synonym: "beta-D-1,2-glucanase activity" EXACT [EC:3.2.1.71] synonym: "endo-(1->2)-beta-D-glucanase activity" EXACT [EC:3.2.1.71] synonym: "endo-1,2-beta-glucanase activity" EXACT [EC:3.2.1.71] xref: EC:3.2.1.71 xref: GO:0033913 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005394 name: xylan 1,3-beta-xylosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of successive xylose residues from the non-reducing termini of 1,3-beta-D-xylans." [EC:3.2.1.72] synonym: "1,3-beta-D-xylan xylohydrolase activity" EXACT [EC:3.2.1.72] synonym: "1,3-beta-D-xylosidase, exo-1,3-beta-xylosidase activity" EXACT [EC:3.2.1.72] synonym: "beta-1,3'-xylanase activity" EXACT [EC:3.2.1.72] synonym: "exo-1,3-beta-xylosidase activity" EXACT [EC:3.2.1.72] synonym: "exo-beta-1,3'-xylanase activity" EXACT [EC:3.2.1.72] xref: EC:3.2.1.72 xref: GO:0033914 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005395 name: mannan 1,2-(1,3)-alpha-mannosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,2- and 1,3-linkages in yeast mannan, releasing mannose." [EC:3.2.1.77] synonym: "1,2-1,3-alpha-D-mannan mannohydrolase activity" EXACT [EC:3.2.1.77] synonym: "exo-1,2-1,3-alpha-mannosidase activity" EXACT [EC:3.2.1.77] xref: EC:3.2.1.77 xref: GO:0033915 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005396 name: beta-agarase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,4-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product." [EC:3.2.1.81] synonym: "AgaA" RELATED [EC:3.2.1.81] synonym: "AgaB" RELATED [EC:3.2.1.81] synonym: "agarase activity" BROAD [EC:3.2.1.81] synonym: "agarose 3-glycanohydrolase activity" BROAD [EC:3.2.1.81] synonym: "agarose 4-glycanohydrolase activity" EXACT [EC:3.2.1.81] xref: EC:3.2.1.81 xref: GO:0033916 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005397 name: exo-poly-alpha-galacturonosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate." [EC:3.2.1.82] synonym: "exopolygalacturanosidase activity" EXACT [EC:3.2.1.82] synonym: "exopolygalacturonosidase activity" EXACT [EC:3.2.1.82] xref: EC:3.2.1.82 xref: GO:0033917 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005398 name: kappa-carrageenase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans." [EC:3.2.1.83] synonym: "kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining) activity" EXACT [EC:3.2.1.83] synonym: "kappa-carrageenan 4-beta-D-glycanohydrolase activity" EXACT [EC:3.2.1.83] xref: EC:3.2.1.83 xref: GO:0033918 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005399 name: glucan 1,3-alpha-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal 1,3-alpha-D-glucosidic links in 1,3-alpha-D-glucans." [EC:3.2.1.84] synonym: "1,3-alpha-D-glucan 3-glucohydrolase activity" EXACT [EC:3.2.1.84] synonym: "exo-1,3-alpha-glucanase activity" EXACT [EC:3.2.1.84] synonym: "glucosidase II activity" EXACT [EC:3.2.1.84] xref: EC:3.2.1.84 xref: GO:0033919 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005400 name: 6-phospho-beta-galactosidase activity namespace: molecular_function def: "Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol." [EC:3.2.1.85] synonym: "6-phospho-beta-D-galactosidase activity" EXACT [EC:3.2.1.85] synonym: "6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity" EXACT [EC:3.2.1.85] synonym: "beta-D-phosphogalactoside galactohydrolase activity" EXACT [EC:3.2.1.85] synonym: "phospho-beta-D-galactosidase activity" EXACT [EC:3.2.1.85] synonym: "phospho-beta-galactosidase activity" EXACT [EC:3.2.1.85] xref: EC:3.2.1.85 xref: GO:0033920 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005401 name: capsular-polysaccharide endo-1,3-alpha-galactosidase activity namespace: molecular_function def: "Catalysis of the reaction: random hydrolysis of 1,3-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide." [EC:3.2.1.87] synonym: "aerobacter-capsular-polysaccharide galactohydrolase activity" EXACT [EC:3.2.1.87] synonym: "capsular polysaccharide galactohydrolase activity" EXACT [EC:3.2.1.87] synonym: "polysaccharide depolymerase activity" EXACT [EC:3.2.1.87] xref: EC:3.2.1.87 xref: GO:0033921 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005402 name: peptidoglycan beta-N-acetylmuramidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal, non-reducing N-acetylmuramic residues." [EC:3.2.1.92] synonym: "beta-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside acetamidodeoxyglucohydrolase activity" EXACT [EC:3.2.1.92] synonym: "exo-beta-acetylmuramidase activity" EXACT [EC:3.2.1.92] synonym: "exo-beta-N-acetylmuramidase activity" EXACT [EC:3.2.1.92] synonym: "peptidoglycan beta-N-acetylmuramoylexohydrolase activity" EXACT [EC:3.2.1.92] xref: EC:3.2.1.92 xref: GO:0033922 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005403 name: glucan 1,6-alpha-isomaltosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,6-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains." [EC:3.2.1.94] synonym: "1,6-alpha-D-glucan isomaltohydrolase activity" EXACT [EC:3.2.1.94] synonym: "exo-isomaltohydrolase activity" EXACT [EC:3.2.1.94] synonym: "G2-dextranase activity" EXACT [EC:3.2.1.94] synonym: "isomalto-dextranase activity" EXACT [EC:3.2.1.94] synonym: "isomaltodextranase activity" EXACT [EC:3.2.1.94] xref: EC:3.2.1.94 xref: GO:0033923 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005404 name: dextran 1,6-alpha-isomaltotriosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,6-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains." [EC:3.2.1.95] synonym: "1,6-alpha-D-glucan isomaltotriohydrolase activity" EXACT [EC:3.2.1.95] synonym: "exo-isomaltotriohydrolase activity" EXACT [EC:3.2.1.95] xref: EC:3.2.1.95 xref: GO:0033924 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005405 name: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact." [EC:3.2.1.96] synonym: "di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] synonym: "endo-beta-(1->4)-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] synonym: "endo-beta-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] synonym: "endo-beta-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] synonym: "endo-beta-N-acetylglucosaminidase D activity" EXACT [EC:3.2.1.96] synonym: "endo-beta-N-acetylglucosaminidase F activity" EXACT [EC:3.2.1.96] synonym: "endo-beta-N-acetylglucosaminidase H activity" EXACT [EC:3.2.1.96] synonym: "endo-beta-N-acetylglucosaminidase L activity" EXACT [EC:3.2.1.96] synonym: "endo-N-acetyl-beta-D-glucosaminidase activity" EXACT [EC:3.2.1.96] synonym: "endo-N-acetyl-beta-glucosaminidase activity" EXACT [EC:3.2.1.96] synonym: "endoglycosidase H activity" EXACT [EC:3.2.1.96] synonym: "endoglycosidase S activity" EXACT [EC:3.2.1.96] synonym: "glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity" EXACT [EC:3.2.1.96] synonym: "glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity" EXACT [EC:3.2.1.96] synonym: "mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity" EXACT [EC:3.2.1.96] synonym: "mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity" EXACT [EC:3.2.1.96] synonym: "N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity" EXACT [EC:3.2.1.96] xref: EC:3.2.1.96 xref: GO:0033925 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005406 name: glycopeptide alpha-N-acetylgalactosaminidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal D-galactosyl-N-acetyl-alpha-D-galactosaminidic residues from a variety of glycopeptides and glycoproteins." [EC:3.2.1.97] synonym: "D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase activity" EXACT [EC:3.2.1.97] synonym: "endo-alpha-acetylgalactosaminidase activity" EXACT [EC:3.2.1.97] synonym: "endo-alpha-N-acetylgalactosaminidase activity" BROAD [EC:3.2.1.97] xref: EC:3.2.1.97 xref: GO:0033926 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005407 name: glucan 1,4-alpha-maltohexaosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends." [EC:3.2.1.98] synonym: "1,4-alpha-D-glucan maltohexaohydrolase activity" EXACT [EC:3.2.1.98] synonym: "exo-maltohexaohydrolase activity" EXACT [EC:3.2.1.98] synonym: "G6-amylase activity" EXACT [EC:3.2.1.98] synonym: "maltohexaose-producing amylase activity" EXACT [EC:3.2.1.98] xref: EC:3.2.1.98 xref: GO:0033927 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005408 name: mannan 1,4-mannobiosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,4-beta-D-mannosidic linkages in 1,4-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends." [EC:3.2.1.100] synonym: "1,4-beta-D-mannan mannobiohydrolase activity" BROAD [EC:3.2.1.100] synonym: "exo-1,4-beta-mannobiohydrolase activity" EXACT [EC:3.2.1.100] synonym: "exo-beta-mannanase activity" EXACT [EC:3.2.1.100] synonym: "mannan 1,4-beta-mannobiosidase activity" EXACT [EC:3.2.1.100] xref: EC:3.2.1.100 xref: GO:0033928 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005409 name: blood-group-substance endo-1,4-beta-galactosidase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,4-beta-D-galactosidic linkages in blood group A and B substances." [EC:3.2.1.102] synonym: "blood-group-substance 1,4-beta-D-galactanohydrolase activity" EXACT [EC:3.2.1.102] synonym: "endo-beta-galactosidase activity" BROAD [EC:3.2.1.102] xref: EC:3.2.1.102 xref: GO:0033929 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005410 name: keratan-sulfate endo-1,4-beta-galactosidase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,4-beta-D-galactosidic linkages in keratan sulfate." [EC:3.2.1.103] synonym: "endo-beta-galactosidase activity" BROAD [EC:3.2.1.103] synonym: "keratan sulfate endogalactosidase activity" EXACT [EC:3.2.1.103] synonym: "keratan-sulfate 1,4-beta-D-galactanohydrolase activity" EXACT [EC:3.2.1.103] synonym: "keratanase activity" EXACT [EC:3.2.1.103] xref: EC:3.2.1.103 xref: GO:0033930 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005411 name: endogalactosaminidase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,4-alpha-D-galactosaminidic linkages in poly(D-galactosamine)." [EC:3.2.1.109] synonym: "galactosaminoglycan glycanohydrolase activity" EXACT [EC:3.2.1.109] xref: EC:3.2.1.109 xref: GO:0033931 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005412 name: 1,3-alpha-L-fucosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,3-linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins." [EC:3.2.1.111] synonym: "3-alpha-L-fucosyl-N-acetylglucosaminyl-glycoprotein fucohydrolase activity" EXACT [EC:3.2.1.111] synonym: "almond emulsin fucosidase I activity" EXACT [EC:3.2.1.111] xref: EC:3.2.1.111 xref: GO:0033932 is_a: CCO:F0000945 ! alpha-L-fucosidase activity [Term] id: CCO:F0005413 name: branched-dextran exo-1,2-alpha-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,2-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose." [EC:3.2.1.115] synonym: "1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase activity" EXACT [EC:3.2.1.115] synonym: "dextran 1,2-alpha-glucosidase activity" EXACT [EC:3.2.1.115] synonym: "dextran alpha-1,2 debranching enzyme" RELATED [EC:3.2.1.115] xref: EC:3.2.1.115 xref: GO:0033933 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005414 name: glucan 1,4-alpha-maltotriohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends." [EC:3.2.1.116] synonym: "1,4-alpha-D-glucan maltotriohydrolase activity" EXACT [EC:3.2.1.116] synonym: "exo-maltotriohydrolase activity" EXACT [EC:3.2.1.116] synonym: "maltotriohydrolase activity" EXACT [EC:3.2.1.116] xref: EC:3.2.1.116 xref: GO:0033934 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005415 name: oligoxyloglucan beta-glycosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,4-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends." [EC:3.2.1.120] synonym: "isoprimeverose-producing oligoxyloglucan hydrolase activity" EXACT [EC:3.2.1.120] synonym: "oligoxyloglucan hydrolase activity" EXACT [EC:3.2.1.120] synonym: "oligoxyloglucan xyloglucohydrolase activity" EXACT [EC:3.2.1.120] xref: EC:3.2.1.120 xref: GO:0033935 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005416 name: polymannuronate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of the D-mannuronide linkages of polymannuronate." [EC:3.2.1.121] synonym: "poly(mannuronide) mannuronohydrolase activity" EXACT [EC:3.2.1.121] synonym: "polymannuronic acid polymerase activity" EXACT [EC:3.2.1.121] xref: EC:3.2.1.121 xref: GO:0033936 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005417 name: 3-deoxy-2-octulosonidase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides." [EC:3.2.1.124] synonym: "2-keto-3-deoxyoctonate hydrolase activity" EXACT [EC:3.2.1.124] synonym: "capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase activity" EXACT [EC:3.2.1.124] synonym: "octulofuranosylono hydrolase activity" EXACT [EC:3.2.1.124] synonym: "octulopyranosylonohydrolase activity" EXACT [EC:3.2.1.124] synonym: "octulosylono hydrolase activity" EXACT [EC:3.2.1.124] xref: EC:3.2.1.124 xref: GO:0033937 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005418 name: 1,6-alpha-L-fucosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,6-linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin." [EC:3.2.1.127] synonym: "1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase activity" EXACT [EC:3.2.1.127] xref: EC:3.2.1.127 xref: GO:0033938 is_a: CCO:F0000945 ! alpha-L-fucosidase activity [Term] id: CCO:F0005419 name: xylan alpha-1,2-glucuronosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of alpha-D-1,2-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans." [EC:3.2.1.131] synonym: "1,2-alpha-glucuronidase activity" EXACT [EC:3.2.1.131] synonym: "alpha-(1->2)-glucuronidase activity" EXACT [EC:3.2.1.131] synonym: "xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity" EXACT [EC:3.2.1.131] xref: EC:3.2.1.131 xref: GO:0033939 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005420 name: glucuronoarabinoxylan endo-1,4-beta-xylanase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,4-beta-D-xylosyl links in some glucuronoarabinoxylans." [EC:3.2.1.136] synonym: "endoarabinoxylanase activity" EXACT [EC:3.2.1.136] synonym: "feraxan endoxylanase activity" EXACT [EC:3.2.1.136] synonym: "feraxanase activity" EXACT [EC:3.2.1.136] synonym: "glucuronoarabinoxylan 1,4-beta-D-xylanohydrolase activity" EXACT [EC:3.2.1.136] synonym: "glucuronoxylan xylanohydrolase activity" EXACT [EC:3.2.1.136] synonym: "glucuronoxylan xylohydrolase activity" EXACT [EC:3.2.1.136] synonym: "glucuronoxylanase activity" EXACT [EC:3.2.1.136] xref: EC:3.2.1.136 xref: GO:0033940 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005421 name: mannan exo-1,2-1,6-alpha-mannosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,2-alpha-D- and 1,6-alpha-D- linkages in yeast mannan, releasing D-mannose." [EC:3.2.1.137] synonym: "1,2-1,6-alpha-D-mannan D-mannohydrolase activity" EXACT [EC:3.2.1.137] synonym: "exo-1,2-1,6-alpha-mannosidase activity" EXACT [EC:3.2.1.137] xref: EC:3.2.1.137 xref: GO:0033941 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005422 name: 4-alpha-D-\{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan." [EC:3.2.1.141] synonym: "4-alpha-D-{(1->4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity" EXACT [EC:3.2.1.141] synonym: "malto-oligosyltrehalose trehalohydrolase activity" EXACT [EC:3.2.1.141] synonym: "maltooligosyl trehalose trehalohydrolase activity" EXACT [EC:3.2.1.141] xref: EC:3.2.1.141 xref: GO:0033942 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005423 name: galactan 1,3-beta-galactosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans." [EC:3.2.1.145] synonym: "galactan (1->3)-beta-D-galactosidase activity" EXACT [EC:3.2.1.145] xref: EC:3.2.1.145 xref: GO:0033943 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005424 name: beta-galactofuranosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose." [EC:3.2.1.146] synonym: "beta-D-galactofuranosidase activity" EXACT [EC:3.2.1.146] synonym: "beta-D-galactofuranoside hydrolase activity" EXACT [EC:3.2.1.146] synonym: "exo-beta-D-galactofuranosidase activity" EXACT [EC:3.2.1.146] synonym: "exo-beta-galactofuranosidase activity" EXACT [EC:3.2.1.146] xref: EC:3.2.1.146 xref: GO:0033944 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005425 name: oligoxyloglucan reducing-end-specific cellobiohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-1,4-linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted." [EC:3.2.1.150] synonym: "oligoxyloglucan reducing end-specific cellobiohydrolase activity" EXACT [EC:3.2.1.150] synonym: "oligoxyloglucan reducing-end cellobiohydrolase activity" EXACT [EC:3.2.1.150] xref: EC:3.2.1.150 xref: GO:0033945 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005426 name: xyloglucan-specific endo-beta-1,4-glucanase activity namespace: molecular_function def: "Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides (endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan)." [EC:3.2.1.151] synonym: "1,4-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.151] synonym: "[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.151] synonym: "XEG" RELATED [EC:3.2.1.151] synonym: "XH" RELATED [EC:3.2.1.151] synonym: "xyloglucan endo-beta-1,4-glucanase activity" EXACT [EC:3.2.1.151] synonym: "xyloglucanase activity" EXACT [EC:3.2.1.151] synonym: "xyloglucanendohydrolase activity" EXACT [EC:3.2.1.151] xref: EC:3.2.1.151 xref: GO:0033946 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005427 name: mannosylglycoprotein endo-beta-mannosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences." [EC:3.2.1.152] synonym: "endo-beta-mannosidase activity" EXACT [EC:3.2.1.152] xref: EC:3.2.1.152 xref: GO:0033947 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005428 name: fructan beta-(2,1)-fructosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal, non-reducing 2,1-linked beta-D-fructofuranose residues in fructans." [EC:3.2.1.153] synonym: "1-FEH II" RELATED [EC:3.2.1.153] synonym: "1-FEH w1" RELATED [EC:3.2.1.153] synonym: "1-FEH w2" RELATED [EC:3.2.1.153] synonym: "1-fructan exohydrolase activity" EXACT [EC:3.2.1.153] synonym: "beta-(2,1)-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.153] synonym: "beta-(2-1)-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.153] synonym: "beta-(2-1)-linkage-specific fructan-beta-fructosidase activity" EXACT [EC:3.2.1.153] synonym: "beta-(2-1)fructan exohydrolase activity" EXACT [EC:3.2.1.153] xref: EC:3.2.1.153 xref: GO:0033948 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005429 name: fructan beta-(2,6)-fructosidase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of terminal, non-reducing 2,6-linked beta-D-fructofuranose residues in fructans." [EC:3.2.1.154] synonym: "6-FEH" RELATED [EC:3.2.1.154] synonym: "beta-(2,6)-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.154] synonym: "beta-(2-6)-fructan exohydrolase activity" EXACT [EC:3.2.1.154] xref: EC:3.2.1.154 xref: GO:0033949 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005430 name: xyloglucan-specific exo-beta-1,4-glucanase activity namespace: molecular_function def: "Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides (exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan)." [EC:3.2.1.155] synonym: "[(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan exo-glucohydrolase activity" EXACT [EC:3.2.1.155] synonym: "Cel74A" RELATED [EC:3.2.1.155] xref: EC:3.2.1.155 xref: GO:0033950 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005431 name: oligosaccharide reducing-end xylanase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides." [EC:3.2.1.156] synonym: "beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity" EXACT [EC:3.2.1.156] synonym: "reducing end xylose-releasing exo-oligoxylanase activity" EXACT [EC:3.2.1.156] synonym: "Rex" RELATED [EC:3.2.1.156] xref: EC:3.2.1.156 xref: GO:0033951 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005432 name: iota-carrageenase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans." [EC:3.2.1.157] synonym: "iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting) activity" EXACT [EC:3.2.1.157] xref: EC:3.2.1.157 xref: GO:0033952 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005433 name: alpha-agarase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product." [EC:3.2.1.158] synonym: "agarase A33 activity" NARROW [EC:3.2.1.158] synonym: "agarase activity" BROAD [EC:3.2.1.158] synonym: "agarose 3-glycanohydrolase activity" BROAD [EC:3.2.1.158] xref: EC:3.2.1.158 xref: GO:0033953 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005434 name: alpha-neoagaro-oligosaccharide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose." [EC:3.2.1.159] synonym: "alpha-NAOS hydrolase activity" EXACT [EC:3.2.1.159] synonym: "alpha-neoagaro-oligosaccharide 3-glycohydrolase activity" EXACT [EC:3.2.1.159] synonym: "alpha-neoagarooligosaccharide hydrolase activity" EXACT [EC:3.2.1.159] xref: EC:3.2.1.159 xref: GO:0033954 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005435 name: beta-apiosyl-beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose." [EC:3.2.1.161] synonym: "7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase activity" EXACT [EC:3.2.1.161] synonym: "furcatin hydrolase activity" EXACT [EC:3.2.1.161] synonym: "isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity" EXACT [EC:3.2.1.161] synonym: "isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity" EXACT [EC:3.2.1.161] xref: EC:3.2.1.161 xref: GO:0033956 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005436 name: lambda-carrageenase activity namespace: molecular_function def: "Catalysis of the reaction: endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S." [EC:3.2.1.162] synonym: "endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase activity" EXACT [EC:3.2.1.162] xref: EC:3.2.1.162 xref: GO:0033957 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005437 name: DNA-deoxyinosine glycosylase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolyses DNA and polynucleotides, releasing free hypoxanthine." [EC:3.2.2.15] synonym: "deoxyribonucleic acid glycosylase activity" EXACT [EC:3.2.2.15] synonym: "DNA(hypoxanthine) glycohydrolase activity" EXACT [EC:3.2.2.15] synonym: "DNA-deoxyinosine deoxyribohydrolase activity" EXACT [EC:3.2.2.15] synonym: "DNA-deoxyinosine glycosidase activity" EXACT [EC:3.2.2.15] synonym: "hypoxanthine-DNA glycosylase activity" EXACT [EC:3.2.2.15] xref: EC:3.2.2.15 xref: GO:0033958 is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0005438 name: deoxyribodipyrimidine endonucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: cleaves the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue." [EC:3.2.2.17] synonym: "deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase activity" EXACT [EC:3.2.2.17] synonym: "deoxyribonucleate pyrimidine dimer glycosidase activity" EXACT [EC:3.2.2.17] synonym: "endonuclease V activity" BROAD [EC:3.2.2.17] synonym: "PD-DNA glycosylase activity" EXACT [EC:3.2.2.17] synonym: "pyrimidine dimer DNA glycosylase activity" EXACT [EC:3.2.2.17] synonym: "pyrimidine dimer DNA-glycosylase activity" EXACT [EC:3.2.2.17] synonym: "T4-induced UV endonuclease activity" EXACT [EC:3.2.2.17] xref: EC:3.2.2.17 xref: GO:0033959 is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0005439 name: N-methyl nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: 7-methylxanthosine + H2O = 7-methylxanthine + D-ribose." [EC:3.2.2.25] synonym: "7-methylxanthosine nucleosidase activity" EXACT [EC:3.2.2.25] synonym: "7-methylxanthosine ribohydrolase activity" EXACT [EC:3.2.2.25] synonym: "methylpurine nucleosidase activity" EXACT [EC:3.2.2.25] synonym: "N-MeNase activity" EXACT [EC:3.2.2.25] synonym: "N-methyl nucleoside hydrolase activity" EXACT [EC:3.2.2.25] xref: EC:3.2.2.25 xref: GO:0033960 is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0005440 name: cis-stilbene-oxide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol." [EC:3.3.2.9] synonym: "arene-oxide hydratase activity" BROAD [EC:3.3.2.9] synonym: "aryl epoxide hydrase activity" BROAD [EC:3.3.2.9] synonym: "benzo(a)pyrene-4,5-epoxide hydratase activity" NARROW [EC:3.3.2.9] synonym: "benzo[a]pyrene-4,5-oxide hydratase activity" NARROW [EC:3.3.2.9] synonym: "cis-epoxide hydrolase activity" EXACT [EC:3.3.2.9] synonym: "epoxide hydrase activity" BROAD [EC:3.3.2.9] synonym: "epoxide hydratase activity" BROAD [EC:3.3.2.9] synonym: "mEH" RELATED [EC:3.3.2.9] synonym: "microsomal epoxide hydrase activity" NARROW [EC:3.3.2.9] synonym: "microsomal epoxide hydratase activity" NARROW [EC:3.3.2.9] synonym: "microsomal epoxide hydrolase activity" NARROW [EC:3.3.2.9] xref: EC:3.3.2.9 xref: GO:0033961 is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0005441 name: cholesterol-5,6-oxide hydrolase activity namespace: molecular_function def: "Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol." [EC:3.3.2.11] synonym: "5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase activity" EXACT [EC:3.3.2.11] synonym: "ChEH" RELATED [EC:3.3.2.11] synonym: "cholesterol-epoxide hydrolase activity" EXACT [EC:3.3.2.11] xref: EC:3.3.2.11 xref: GO:0033963 is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0005442 name: glycosphingolipid deacylase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives." [EC:3.5.1.69] synonym: "glycosphingolipid amidohydrolase activity" EXACT [EC:3.5.1.69] synonym: "glycosphingolipid ceramide deacylase activity" BROAD [EC:3.5.1.69] xref: EC:3.5.1.69 xref: GO:0033964 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005443 name: aculeacin-A deacylase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain." [EC:3.5.1.70] synonym: "aculeacin A acylase activity" EXACT [EC:3.5.1.70] synonym: "aculeacin-A amidohydrolase activity" EXACT [EC:3.5.1.70] xref: EC:3.5.1.70 xref: GO:0033965 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005444 name: N-substituted formamide deformylase activity namespace: molecular_function def: "Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine." [EC:3.5.1.91] synonym: "N-benzylformamide amidohydrolase activity" EXACT [EC:3.5.1.91] synonym: "NfdA" RELATED [EC:3.5.1.91] xref: GO:0033966 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005445 name: glutaryl-7-aminocephalosporanic-acid acylase activity namespace: molecular_function def: "Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate." [EC:3.5.1.93] synonym: "(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase activity" EXACT [EC:3.5.1.93] synonym: "7beta-(4-carboxybutanamido)cephalosporanic acid acylase activity" EXACT [EC:3.5.1.93] synonym: "CA" RELATED [EC:3.5.1.93] synonym: "cephalosporin acylase activity" EXACT [EC:3.5.1.93] synonym: "cephalosporin C acylase activity" EXACT [EC:3.5.1.93] synonym: "GA" RELATED [EC:3.5.1.93] synonym: "GCA" RELATED [EC:3.5.1.93] synonym: "GL-7-ACA acylase activity" EXACT [EC:3.5.1.93] synonym: "glutaryl-7-ACA acylase activity" EXACT [EC:3.5.1.93] synonym: "glutaryl-7-aminocephalosporanic acid acylase activity" EXACT [EC:3.5.1.93] xref: EC:3.5.1.93 xref: GO:0033968 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005446 name: gamma-glutamyl-gamma-aminobutyrate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate." [EC:3.5.1.94] synonym: "4-(glutamylamino)butanoate amidohydrolase activity" EXACT [EC:3.5.1.94] synonym: "gamma-glutamyl-GABA hydrolase activity" EXACT [EC:3.5.1.94] synonym: "PuuD" RELATED [EC:3.5.1.94] synonym: "YcjL" RELATED [EC:3.5.1.94] xref: EC:3.5.1.94 xref: GO:0033969 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005447 name: N-malonylurea hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H2O = malonate + urea." [EC:3.5.1.95] synonym: "3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) activity" EXACT [EC:3.5.1.95] synonym: "ureidomalonase activity" EXACT [EC:3.5.1.95] xref: EC:3.5.1.95 xref: GO:0033970 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005448 name: hydroxyisourate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate." [EC:3.5.2.17] synonym: "5-hydroxyisourate amidohydrolase activity" EXACT [EC:3.5.2.17] synonym: "5-hydroxyisourate hydrolase activity" EXACT [EC:3.5.2.17] synonym: "HIUHase activity" EXACT [EC:3.5.2.17] xref: EC:3.5.2.17 xref: GO:0033971 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0005449 name: proclavaminate amidinohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: amidinoproclavaminate + H2O = proclavaminate + urea." [EC:3.5.3.22] synonym: "PAH" RELATED [EC:3.5.3.22] synonym: "proclavaminate amidino hydrolase activity" EXACT [EC:3.5.3.22] synonym: "proclavaminic acid amidino hydrolase activity" EXACT [EC:3.5.3.22] xref: EC:3.5.3.22 xref: GO:0033972 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0005450 name: dCTP deaminase (dUMP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: dCTP + 2 H2O = dUMP + diphosphate + NH3." [EC:3.5.4.30] synonym: "dCTP aminohydrolase (dUMP-forming) activity" EXACT [EC:3.5.4.30] xref: EC:3.5.4.30 xref: GO:0033973 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0005451 name: nucleoside phosphoacylhydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolyses mixed phospho-anhydride bonds." [EC:3.6.1.24] synonym: "nucleoside-5'-phosphoacylate acylhydrolase activity" EXACT [EC:3.6.1.24] xref: EC:3.6.1.24 xref: GO:0033974 is_a: CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Term] id: CCO:F0005453 name: 2-haloacid dehalogenase (configuration-inverting) activity namespace: molecular_function def: "Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide." [EC:3.8.1.10] synonym: "2-haloalkanoic acid dehalogenase activity" BROAD [EC:3.8.1.10] synonym: "2-haloalkanoid acid halidohydrolase activity" BROAD [EC:3.8.1.10] synonym: "DL-2-haloacid dehalogenase (inversion of configuration) activity" EXACT [EC:3.8.1.10] synonym: "DL-2-haloacid dehalogenase activity" BROAD [EC:3.8.1.10] synonym: "DL-2-haloacid halidohydrolase (inversion of configuration) activity" EXACT [EC:3.8.1.10] synonym: "DL-DEXi" RELATED [EC:3.8.1.10] xref: EC:3.8.1.10 xref: GO:0033976 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0005454 name: 2-haloacid dehalogenase (configuration-retaining) activity namespace: molecular_function def: "Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide." [EC:3.8.1.11] synonym: "2-haloalkanoic acid dehalogenase activity" BROAD [EC:3.8.1.11] synonym: "2-haloalkanoid acid halidohydrolase activity" BROAD [EC:3.8.1.11] synonym: "DL-2-haloacid dehalogenase activity" BROAD [EC:3.8.1.11] synonym: "DL-DEXr" RELATED [EC:3.8.1.11] xref: EC:3.8.1.11 xref: GO:0033977 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0005455 name: phosphonopyruvate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phosphonopyruvate + H2O = pyruvate + phosphate." [EC:3.11.1.3] synonym: "PPH" RELATED [EC:3.11.1.3] xref: EC:3.11.1.3 xref: GO:0033978 is_a: CCO:F0003394 ! hydrolase activity, acting on acid carbon-phosphorus bonds [Term] id: CCO:F0005456 name: phosphonopyruvate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phosphonopyruvate = 2-phosphonoacetaldehyde + CO2." [EC:4.1.1.82] synonym: "3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming) activity" EXACT [EC:4.1.1.82] synonym: "3-phosphonopyruvate carboxy-lyase activity" EXACT [EC:4.1.1.82] xref: EC:4.1.1.82 xref: GO:0033980 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0005457 name: D-dopachrome decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: D-dopachrome = 5,6-dihydroxyindole + CO2." [EC:4.1.1.84] synonym: "D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming) activity" EXACT [EC:4.1.1.84] synonym: "D-dopachrome carboxy-lyase activity" EXACT [EC:4.1.1.84] synonym: "D-dopachrome tautomerase activity" EXACT [EC:4.1.1.84] synonym: "D-tautomerase activity" EXACT [EC:4.1.1.84] synonym: "phenylpyruvate tautomerase II activity" EXACT [EC:4.1.1.84] xref: EC:4.1.1.84 xref: GO:0033981 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0005458 name: 3-dehydro-L-gulonate-6-phosphate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H+ = L-xylulose 5-phosphate + CO2." [EC:4.1.1.85] synonym: "3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity" EXACT [EC:4.1.1.85] synonym: "3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity" EXACT [EC:4.1.1.85] synonym: "3-keto-L-gulonate 6-phosphate decarboxylase activity" EXACT [EC:4.1.1.85] synonym: "KGPDC" RELATED [EC:4.1.1.85] synonym: "SgaH" RELATED [EC:4.1.1.85] synonym: "SgbH" RELATED [EC:4.1.1.85] synonym: "UlaD" RELATED [EC:4.1.1.85] xref: EC:4.1.1.85 xref: GO:0033982 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0005459 name: diaminobutyrate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-2,4-diaminobutanoate = propane-1,3-diamine + CO2." [EC:4.1.1.86] synonym: "DABA DC" RELATED [EC:4.1.1.86] synonym: "L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming) activity" EXACT [EC:4.1.1.86] synonym: "L-2,4-diaminobutanoate carboxy-lyase activity" EXACT [EC:4.1.1.86] synonym: "L-2,4-diaminobutyrate decarboxylase activity" EXACT [EC:4.1.1.86] xref: EC:4.1.1.86 xref: GO:0033983 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0005460 name: indole-3-glycerol-phosphate lyase activity namespace: molecular_function def: "Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate." [EC:4.1.2.8] synonym: "(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase (indole-forming) activity" EXACT [EC:4.1.2.8] synonym: "(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.8] synonym: "BX1" RELATED [EC:4.1.2.8] synonym: "IGL" RELATED [EC:4.1.2.8] synonym: "indole glycerol phosphate hydrolase activity" EXACT [EC:4.1.2.8] synonym: "indole synthase activity" EXACT [EC:4.1.2.8] synonym: "indole-3-glycerol phosphate lyase activity" EXACT [EC:4.1.2.8] synonym: "indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity" EXACT [EC:4.1.2.8] synonym: "indoleglycerolphosphate aldolase activity" EXACT [EC:4.1.2.8] synonym: "tryptophan synthase alpha activity" EXACT [EC:4.1.2.8] synonym: "TSA" RELATED [EC:4.1.2.8] xref: EC:4.1.2.8 xref: GO:0033984 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0005461 name: 2-hydroxyisoflavanone dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O." [EC:4.2.1.105] synonym: "2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming) activity" EXACT [EC:4.2.1.105] synonym: "2,7,4'-trihydroxyisoflavanone hydro-lyase activity" EXACT [EC:4.2.1.105] xref: EC:4.2.1.105 xref: GO:0033987 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005462 name: bile-acid 7alpha-dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-enoate = 12alpha-hydroxy-3-oxochola-4,6-dienoate + H2O." [EC:4.2.1.106] synonym: "7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoate-forming) activity" EXACT [EC:4.2.1.106] synonym: "7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase activity" EXACT [EC:4.2.1.106] synonym: "BA7 alpha dehydratase activity" EXACT [EC:4.2.1.106] xref: EC:4.2.1.106 xref: GO:0033988 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005463 name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O." [EC:4.2.1.107] synonym: "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity" EXACT [EC:4.2.1.107] synonym: "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.107] synonym: "46 kDa hydratase 2 activity" EXACT [EC:4.2.1.107] synonym: "D-3-hydroxyacyl-CoA dehydratase activity" BROAD [EC:4.2.1.107] xref: EC:4.2.1.107 xref: GO:0033989 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005464 name: ectoine synthase activity namespace: molecular_function def: "Catalysis of the reaction: N4-acetyl-L-2,4-diaminobutanoate = L-ectoine + H2O." [EC:4.2.1.108] synonym: "4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity" EXACT [EC:4.2.1.108] synonym: "EctC" RELATED [EC:4.2.1.108] synonym: "L-ectoine synthase activity" EXACT [EC:4.2.1.108] synonym: "N-acetyldiaminobutanoate dehydratase activity" EXACT [EC:4.2.1.108] synonym: "N-acetyldiaminobutyrate dehydratase activity" EXACT [EC:4.2.1.108] synonym: "N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity" EXACT [EC:4.2.1.108] xref: EC:4.2.1.108 xref: GO:0033990 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005465 name: aldos-2-ulose dehydratase activity namespace: molecular_function def: "Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O (overall reaction), (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one." [EC:4.2.1.110] synonym: "1,5-anhydro-D-fructose dehydratase (microthecin-forming) activity" EXACT [EC:4.2.1.110] synonym: "1,5-anhydro-D-fructose hydro-lyase (microthecin-forming) activity" EXACT [EC:4.2.1.110] synonym: "AUDH" RELATED [EC:4.2.1.110] synonym: "pyranosone dehydratase activity" EXACT [EC:4.2.1.110] xref: EC:4.2.1.110 xref: GO:0033991 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005466 name: 1,5-anhydro-D-fructose dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O." [EC:4.2.1.111] synonym: "1,5-anhydro-D-arabino-hex-2-ulose dehydratase activity" EXACT [EC:4.2.1.111] synonym: "1,5-anhydro-D-fructose 4-dehydratase activity" EXACT [EC:4.2.1.111] synonym: "1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming) activity" EXACT [EC:4.2.1.111] synonym: "1,5-anhydro-D-fructose hydro-lyase activity" EXACT [EC:4.2.1.111] synonym: "1,5-anhydro-D-fructose hydrolyase activity" EXACT [EC:4.2.1.111] synonym: "AF dehydratase activity" EXACT [EC:4.2.1.111] synonym: "AFDH" RELATED [EC:4.2.1.111] xref: EC:4.2.1.111 xref: GO:0033992 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005467 name: glucuronan lyase activity namespace: molecular_function def: "Catalysis of the reaction: Eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides." [EC:4.2.2.14] synonym: "(1,4)-beta-D-glucuronan lyase activity" EXACT [EC:4.2.2.14] xref: EC:4.2.2.14 xref: GO:0033994 is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0005468 name: anhydrosialidase activity namespace: molecular_function def: "Catalysis of the reaction: Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate." [EC:4.2.2.15] synonym: "anhydroneuraminidase activity" EXACT [EC:4.2.2.15] synonym: "glycoconjugate sialyl-lyase (2,7-cyclizing) activity" EXACT [EC:4.2.2.15] synonym: "sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing) activity" EXACT [EC:4.2.2.15] synonym: "sialidase L activity" EXACT [EC:4.2.2.15] xref: EC:4.2.2.15 xref: GO:0033995 is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0005469 name: levan fructotransferase (DFA-IV-forming) activity namespace: molecular_function def: "Catalysis of the reaction: Produces di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide." [EC:4.2.2.16] synonym: "2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-fructofuranose 2,6':2',6-dianhydride) activity" EXACT [EC:4.2.2.16] synonym: "2,6-beta-D-fructan lyase (di-beta-D-fructofuranose-2,6':2',6-dianhydride-forming) activity" EXACT [EC:4.2.2.16] synonym: "levan fructotransferase activity" EXACT [EC:4.2.2.16] xref: EC:4.2.2.16 xref: GO:0033996 is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0005470 name: inulin fructotransferase (DFA-I-forming) activity namespace: molecular_function def: "Catalysis of the reaction: Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide." [EC:4.2.2.17] synonym: "2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,1'-dianhydride-forming) activity" EXACT [EC:4.2.2.17] synonym: "inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming) activity" EXACT [EC:4.2.2.17] synonym: "inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':1',2-dianhydride) activity" EXACT [EC:4.2.2.17] synonym: "inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming) activity" EXACT [EC:4.2.2.17] synonym: "inulin fructotransferase (DFA-I-producing) activity" EXACT [EC:4.2.2.17] xref: EC:4.2.2.17 xref: GO:0033997 is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0005471 name: inulin fructotransferase (DFA-III-forming) activity namespace: molecular_function def: "Catalysis of the reaction: Produces alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide." [EC:4.2.2.18] synonym: "2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride-forming) activity" EXACT [EC:4.2.2.18] synonym: "inulase II activity" EXACT [EC:4.2.2.18] synonym: "inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming) activity" EXACT [EC:4.2.2.18] synonym: "inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride) activity" EXACT [EC:4.2.2.18] synonym: "inulin fructotransferase (depolymerizing) activity" EXACT [EC:4.2.2.18] synonym: "inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming) activity" EXACT [EC:4.2.2.18] synonym: "inulin fructotransferase (DFA-III-producing) activity" EXACT [EC:4.2.2.18] synonym: "inulinase II activity" EXACT [EC:4.2.2.18] xref: EC:4.2.2.18 xref: GO:0033998 is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0005472 name: chondroitin B lyase activity namespace: molecular_function def: "Catalysis of the reaction: Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S)." [EC:4.2.2.19] synonym: "ChnB" RELATED [EC:4.2.2.19] synonym: "chonB" RELATED [EC:4.2.2.19] synonym: "chondroitinase B activity" EXACT [EC:4.2.2.19] xref: EC:4.2.2.19 xref: GO:0033999 is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0005473 name: chondroitin-sulfate-ABC endolyase activity namespace: molecular_function def: "Catalysis of the reaction: Endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides." [EC:4.2.2.20] synonym: "chondroitin ABC eliminase activity" BROAD [EC:4.2.2.20] synonym: "chondroitin sulfate ABC endoeliminase activity" EXACT [EC:4.2.2.20] synonym: "chondroitin sulfate ABC endolyase activity" EXACT [EC:4.2.2.20] synonym: "chondroitin sulfate ABC lyase activity" BROAD [EC:4.2.2.20] synonym: "chondroitinase ABC activity" BROAD [EC:4.2.2.20] synonym: "chondroitinase activity" BROAD [EC:4.2.2.20] synonym: "ChS ABC lyase activity" BROAD [EC:4.2.2.20] synonym: "ChS ABC lyase I activity" EXACT [EC:4.2.2.20] xref: EC:4.2.2.20 xref: GO:0034000 is_a: CCO:F0006792 ! chondroitin ABC lyase activity [Term] id: CCO:F0005474 name: chondroitin-sulfate-ABC exolyase activity namespace: molecular_function def: "Catalysis of the reaction: Exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments." [EC:4.2.2.21] synonym: "chondroitin ABC eliminase activity" BROAD [EC:4.2.2.21] synonym: "chondroitin sulfate ABC exoeliminase activity" EXACT [EC:4.2.2.21] synonym: "chondroitin sulfate ABC exolyase activity" EXACT [EC:4.2.2.21] synonym: "chondroitin sulfate ABC lyase activity" BROAD [EC:4.2.2.21] synonym: "chondroitinase ABC activity" BROAD [EC:4.2.2.21] synonym: "chondroitinase activity" BROAD [EC:4.2.2.21] synonym: "ChS ABC lyase activity" BROAD [EC:4.2.2.21] synonym: "ChS ABC lyase II activity" EXACT [EC:4.2.2.21] xref: EC:4.2.2.21 xref: GO:0034001 is_a: CCO:F0006792 ! chondroitin ABC lyase activity [Term] id: CCO:F0005476 name: vetispiradiene synthase activity namespace: molecular_function def: "Catalysis of the reaction: trans,trans-farnesyl diphosphate = vetispiradiene + diphosphate." [EC:4.2.3.21] synonym: "HVS" RELATED [EC:4.2.3.21] synonym: "pemnaspirodiene synthase activity" EXACT [EC:4.2.3.21] synonym: "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity" EXACT [EC:4.2.3.21] synonym: "vetispiradiene cyclase activity" EXACT [EC:4.2.3.21] synonym: "vetispiradiene-forming farnesyl pyrophosphate cyclase activity" EXACT [EC:4.2.3.21] xref: EC:4.2.3.21 xref: GO:0034003 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005477 name: germacradienol synthase activity namespace: molecular_function def: "Catalysis of the reactions: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate and 2-trans,6-trans-farnesyl diphosphate = (-)-(7S)-germacrene D + diphosphate." [EC:4.2.3.22] synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity" EXACT [EC:4.2.3.22] synonym: "germacradienol/germacrene-D synthase activity" EXACT [EC:4.2.3.22] xref: EC:4.2.3.22 xref: GO:0034004 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005478 name: germacrene-A synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate." [EC:4.2.3.23] synonym: "(+)-(10R)-germacrene A synthase activity" EXACT [EC:4.2.3.23] synonym: "(+)-germacrene A synthase activity" EXACT [EC:4.2.3.23] synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity" EXACT [EC:4.2.3.23] synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity" EXACT [EC:4.2.3.23] synonym: "GAS" RELATED [EC:4.2.3.23] synonym: "germacrene A synthase activity" EXACT [EC:4.2.3.23] xref: EC:4.2.3.23 xref: GO:0034005 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005479 name: amorpha-4,11-diene synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate." [EC:4.2.3.24] synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming) activity" EXACT [EC:4.2.3.24] synonym: "amorphadiene synthase activity" EXACT [EC:4.2.3.24] xref: EC:4.2.3.24 xref: GO:0034006 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005480 name: S-linalool synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate + H2O = (3S)-linalool + diphosphate." [EC:4.2.3.25] synonym: "3S-linalool synthase activity" EXACT [EC:4.2.3.25] synonym: "geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming] activity" EXACT [EC:4.2.3.25] synonym: "LIS" RELATED [EC:4.2.3.25] synonym: "Lis" RELATED [EC:4.2.3.25] xref: EC:4.2.3.25 xref: GO:0034007 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005481 name: R-linalool synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate + H2O = (3R)-linalool + diphosphate." [EC:4.2.3.26] synonym: "(-)-3R-linalool synthase activity" EXACT [EC:4.2.3.26] synonym: "(3R)-linalool synthase activity" EXACT [EC:4.2.3.26] synonym: "geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] activity" EXACT [EC:4.2.3.26] xref: EC:4.2.3.26 xref: GO:0034008 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005482 name: isoprene synthase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylallyl diphosphate = isoprene + diphosphate." [EC:4.2.3.27] synonym: "dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming) activity" EXACT [EC:4.2.3.27] synonym: "ISPC" RELATED [EC:4.2.3.27] synonym: "ISPS" RELATED [EC:4.2.3.27] xref: EC:4.2.3.27 xref: GO:0034009 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005483 name: sulfolactate sulfo-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 3-sulfolactate = pyruvate + bisulfite." [EC:4.4.1.24] synonym: "3-sulfolactate bisulfite-lyase (pyruvate-forming) activity" EXACT [EC:4.4.1.24] synonym: "3-sulfolactate bisulfite-lyase activity" EXACT [EC:4.4.1.24] synonym: "Suy" RELATED [EC:4.4.1.24] synonym: "SuyAB" RELATED [EC:4.4.1.24] xref: EC:4.4.1.24 xref: GO:0034010 is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0005484 name: L-cysteate sulfo-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-cysteate + H2O = pyruvate + bisulfite + NH3." [EC:4.4.1.25] synonym: "CuyA" RELATED [EC:4.4.1.25] synonym: "L-cysteate bisulfite-lyase (deaminating; pyruvate-forming) activity" EXACT [EC:4.4.1.25] synonym: "L-cysteate sulfo-lyase (deaminating) activity" EXACT [EC:4.4.1.25] xref: EC:4.4.1.25 xref: GO:0034011 is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0005485 name: FAD-AMP lyase (cyclizing) activity namespace: molecular_function def: "Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate." [EC:4.6.1.15] synonym: "FAD AMP-lyase (cyclic-FMN-forming) activity" EXACT [EC:4.6.1.15] synonym: "FAD AMP-lyase (riboflavin-cyclic-4',5'-phosphate-forming) activity" EXACT [EC:4.6.1.15] synonym: "FMN cyclase activity" EXACT [EC:4.6.1.15] xref: EC:4.6.1.15 xref: GO:0034012 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0005486 name: aliphatic aldoxime dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O." [EC:4.99.1.5] synonym: "aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming) activity" EXACT [EC:4.99.1.5] synonym: "aliphatic aldoxime hydro-lyase activity" EXACT [EC:4.99.1.5] synonym: "OxdA" RELATED [EC:4.99.1.5] xref: EC:4.99.1.5 xref: GO:0034013 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0005487 name: L-ribulose-5-phosphate 3-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate." [EC:5.1.3.22] synonym: "L-xylulose 5-phosphate 3-epimerase activity" EXACT [EC:5.1.3.22] synonym: "SgaU" RELATED [EC:5.1.3.22] synonym: "UlaE" RELATED [EC:5.1.3.22] xref: EC:5.1.3.22 xref: GO:0034015 is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0005488 name: polyenoic fatty acid isomerase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate = (5Z,7E,8E,14Z,17Z)-eicosapentaenoate." [EC:5.3.3.13] synonym: "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity" EXACT [EC:5.3.3.13] synonym: "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity" EXACT [EC:5.3.3.13] synonym: "(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity" EXACT [EC:5.3.3.13] synonym: "eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity" EXACT [EC:5.3.3.13] synonym: "PFI" RELATED [EC:5.3.3.13] xref: EC:5.3.3.13 xref: GO:0034016 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0005489 name: trans-2-decenoyl-acyl-carrier-protein isomerase activity namespace: molecular_function def: "Catalysis of the reaction: trans-dec-2-enoyl-acyl-carrier-protein = cis-dec-3-enoyl-acyl-carrier-protein." [EC:5.3.3.14] synonym: "beta-hydroxydecanoyl thioester dehydrase activity" BROAD [EC:5.3.3.14] synonym: "decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity" EXACT [EC:5.3.3.14] synonym: "FabM" RELATED [EC:5.3.3.14] synonym: "trans-2,cis-3-decenoyl-ACP isomerase activity" EXACT [EC:5.3.3.14] synonym: "trans-2-cis-3-decenoyl-ACP isomerase activity" EXACT [EC:5.3.3.14] synonym: "trans-2-decenoyl-ACP isomerase activity" EXACT [EC:5.3.3.14] xref: EC:5.3.3.14 xref: GO:0034017 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0005490 name: ascopyrone tautomerase activity namespace: molecular_function def: "Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose." [EC:5.3.3.15] synonym: "1,5-anhydro-D-glycero-hex-3-en-2-ulose delta3-delta1-isomerase activity" EXACT [EC:5.3.3.15] synonym: "1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase activity" EXACT [EC:5.3.3.15] synonym: "APM tautomerase activity" EXACT [EC:5.3.3.15] synonym: "APTM" RELATED [EC:5.3.3.15] synonym: "ascopyrone intramolecular oxidoreductase activity" EXACT [EC:5.3.3.15] synonym: "ascopyrone isomerase activity" EXACT [EC:5.3.3.15] synonym: "ascopyrone P tautomerase activity" EXACT [EC:5.3.3.15] xref: EC:5.3.3.15 xref: GO:0034018 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0005491 name: capsanthin/capsorubin synthase activity namespace: molecular_function def: "Catalysis of the reactions: violaxanthin = capsorubin and antheraxanthin = capsanthin." [EC:5.3.99.8] synonym: "capsanthin-capsorubin synthase activity" EXACT [EC:5.3.99.8] synonym: "CCS" RELATED [EC:5.3.99.8] synonym: "ketoxanthophyll synthase activity" EXACT [EC:5.3.99.8] synonym: "violaxanthin-capsorubin isomerase (ketone-forming) activity" EXACT [EC:5.3.99.8] xref: EC:5.3.99.8 xref: GO:0034019 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0005492 name: neoxanthin synthase activity namespace: molecular_function def: "Catalysis of the reaction: violaxanthin = neoxanthin." [EC:5.3.99.9] synonym: "NSY" RELATED [EC:5.3.99.9] synonym: "violaxanthin-neoxanthin isomerase (epoxide-opening) activity" EXACT [EC:5.3.99.9] xref: EC:5.3.99.9 xref: GO:0034020 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0005493 name: 3-(hydroxyamino)phenol mutase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone." [EC:5.4.4.3] synonym: "3-(hydroxyamino)phenol hydroxymutase activity" EXACT [EC:5.4.4.3] synonym: "3-hydroxylaminophenol mutase activity" EXACT [EC:5.4.4.3] synonym: "3HAP mutase activity" EXACT [EC:5.4.4.3] xref: EC:5.4.4.3 xref: GO:0034022 xref: UM-BBD_enzymeID:e0953 is_a: CCO:F0007827 ! intramolecular transferase activity, transferring hydroxy groups [Term] id: CCO:F0005494 name: 5-(carboxyamino)imidazole ribonucleotide mutase activity namespace: molecular_function def: "Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate." [EC:5.4.99.18] synonym: "5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase activity" EXACT [EC:5.4.99.18] synonym: "class I PurE" RELATED [EC:5.4.99.18] synonym: "N5-CAIR mutase activity" EXACT [EC:5.4.99.18] synonym: "N5-carboxyaminoimidazole ribonucleotide mutase activity" EXACT [EC:5.4.99.18] synonym: "PurE" RELATED [EC:5.4.99.18] xref: EC:5.4.99.18 xref: GO:0034023 is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0005495 name: glutamate-putrescine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate + putrescine = ADP + phosphate + gamma-L-glutamylputrescine." [EC:6.3.1.11] synonym: "gamma-glutamylputrescine synthetase activity" EXACT [EC:6.3.1.11] synonym: "L-glutamate:putrescine ligase (ADP-forming) activity" EXACT [EC:6.3.1.11] synonym: "YcjK" RELATED [EC:6.3.1.11] xref: EC:6.3.1.11 xref: GO:0034024 is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0005496 name: D-aspartate ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate." [EC:6.3.1.12] synonym: "aslfm" RELATED [EC:6.3.1.12] synonym: "D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming) activity" EXACT [EC:6.3.1.12] synonym: "D-aspartic acid-activating enzyme" RELATED [EC:6.3.1.12] synonym: "UDP-MurNAc-pentapeptide:D-aspartate ligase activity" EXACT [EC:6.3.1.12] xref: EC:6.3.1.12 xref: GO:0034025 is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0005497 name: L-amino-acid alpha-ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid." [EC:6.3.2.28] synonym: "bacilysin synthetase activity" EXACT [EC:6.3.2.28] synonym: "L-amino acid alpha-ligase activity" EXACT [EC:6.3.2.28] synonym: "L-amino acid ligase activity" EXACT [EC:6.3.2.28] synonym: "YwfE" RELATED [EC:6.3.2.28] xref: EC:6.3.2.28 xref: GO:0034026 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0005499 name: 5-(carboxyamino)imidazole ribonucleotide synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO3- = ADP + phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole." [EC:6.3.4.18] synonym: "5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity" EXACT [EC:6.3.4.18] synonym: "N5-CAIR synthetase activity" EXACT [EC:6.3.4.18] synonym: "N5-carboxyaminoimidazole ribonucleotide synthetase activity" EXACT [EC:6.3.4.18] synonym: "PurK" RELATED [EC:6.3.4.18] xref: EC:6.3.4.18 xref: GO:0034028 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0005500 name: 2-oxoglutarate carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-oxoglutarate + HCO3- = ADP + phosphate + oxalosuccinate." [EC:6.4.1.7] synonym: "carboxylating factor for ICDH" RELATED [EC:6.4.1.7] synonym: "CFI" RELATED [EC:6.4.1.7] synonym: "OGC" RELATED [EC:6.4.1.7] synonym: "oxalosuccinate synthetase activity" EXACT [EC:6.4.1.7] xref: EC:6.4.1.7 xref: GO:0034029 is_a: CCO:F0003443 ! ligase activity, forming carbon-carbon bonds [Term] id: CCO:F0005501 name: deoxyhypusine synthase activity namespace: molecular_function def: "Catalysis of the reaction: eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+." [EC:2.5.1.46, GOC:pd, MetaCyc:2.5.1.46-RXN] comment: Note that this term is equivalent to the obsolete molecular function term 'deoxyhypusine synthase activity ; GO:0004171' and corresponds closely to the biological process term 'spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase ; GO:0050983'. synonym: "eIF-5A-deoxyhypusine synthase activity" EXACT [EC:2.5.1.46] synonym: "eIF5A-precursor-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity" EXACT [EC:2.5.1.46] synonym: "spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity" EXACT [EC:2.5.1.46] xref: EC:2.5.1.46 xref: GO:0034038 xref: MetaCyc:2.5.1.46-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005502 name: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar." [GOC:mah, PMID:17641464] synonym: "8-oxoG DNA N-glycosylase activity" EXACT [] xref: GO:0034039 is_a: CCO:F0001984 ! oxidized purine base lesion DNA N-glycosylase activity [Term] id: CCO:F0005503 name: lipid-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out)." [GOC:rl] xref: GO:0034040 is_a: CCO:F0001556 ! lipid transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0005504 name: sterol-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out)." [GOC:rl] xref: GO:0034041 is_a: CCO:F0002716 ! sterol transporter activity is_a: CCO:F0005503 ! lipid-transporting ATPase activity [Term] id: CCO:F0005505 name: 5-formyluracil DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar." [GOC:mah, PMID:17641464] synonym: "5-foU DNA N-glycosylase activity" EXACT [] xref: GO:0034042 is_a: CCO:F0000096 ! oxidized pyrimidine base lesion DNA N-glycosylase activity [Term] id: CCO:F0005506 name: 5-hydroxymethyluracil DNA N-glycosylase activity namespace: molecular_function def: "Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar." [GOC:mah, PMID:17641464] synonym: "5-hmU DNA N-glycosylase activity" EXACT [] xref: GO:0034043 is_a: CCO:F0000096 ! oxidized pyrimidine base lesion DNA N-glycosylase activity [Term] id: CCO:F0005507 name: poly(rG) binding namespace: molecular_function def: "Interacting selectively with a sequence of guanine residues in an RNA molecule." [GOC:mah] synonym: "poly(G) binding" BROAD [] xref: GO:0034046 is_a: CCO:F0000312 ! single-stranded RNA binding [Term] id: CCO:F0005508 name: estrogen response element binding namespace: molecular_function def: "Interacting selectively with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen." [GOC:ecd, PMID:15036253, PMID:17975005] synonym: "ERE binding" EXACT [] xref: GO:0034056 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0005509 name: RNA strand-exchange activity namespace: molecular_function def: "Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity." [GOC:mcc, PMID:9769100] xref: GO:0034057 is_a: CCO:F0000310 ! double-stranded RNA binding is_a: CCO:F0000312 ! single-stranded RNA binding [Term] id: CCO:F0005510 name: DNA polymerase activity namespace: molecular_function def: "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and primer." [EC:2.7.7.7, GOC:mah] subset: gosubset_prok synonym: "deoxynucleate polymerase activity" EXACT [EC:2.7.7.7] synonym: "deoxyribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.7] synonym: "deoxyribonucleic acid polymerase activity" EXACT [EC:2.7.7.7] synonym: "deoxyribonucleic polymerase activity" EXACT [EC:2.7.7.7] synonym: "DNA nucleotidyltransferase activity" EXACT [EC:2.7.7.7] xref: GO:0034061 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0005511 name: RNA polymerase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template." [EC:2.7.7.6, GOC:mah] subset: gosubset_prok synonym: "C ribonucleic acid formation factors" RELATED [EC:2.7.7.6] synonym: "C RNA formation factors" RELATED [EC:2.7.7.6] synonym: "ribonucleate nucleotidyltransferase activity" EXACT [EC:2.7.7.6] synonym: "ribonucleate polymerase activity" EXACT [EC:2.7.7.6] synonym: "ribonucleic acid nucleotidyltransferase" BROAD [EC:2.7.7.6] synonym: "ribonucleic acid polymerase activity" EXACT [EC:2.7.7.6] synonym: "ribonucleic acid transcriptase activity" EXACT [EC:2.7.7.6] synonym: "ribonucleic polymerase activity" EXACT [EC:2.7.7.6] synonym: "ribonucleic transcriptase activity" EXACT [EC:2.7.7.6] synonym: "RNA nucleotidyltransferase activity" EXACT [EC:2.7.7.6] synonym: "RNA transcriptase activity" EXACT [EC:2.7.7.6] synonym: "transcriptase" BROAD [EC:2.7.7.6] xref: GO:0034062 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0005512 name: aminoglycoside nucleotidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside." [GOC:cb] subset: gosubset_prok synonym: "aminoglycoside adenylyltransferase activity" NARROW [] synonym: "streptomycin adenylate synthetase activity" NARROW [EC:2.7.7.47] synonym: "streptomycin adenyltransferase activity" NARROW [EC:2.7.7.47] synonym: "streptomycin adenylylase activity" NARROW [EC:2.7.7.47] synonym: "streptomycin adenylyltransferase activity" NARROW [EC:2.7.7.47] synonym: "streptomycin-spectinomycin adenylyltransferase activity" NARROW [EC:2.7.7.47] xref: GO:0034068 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0005513 name: aminoglycoside N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside." [GOC:cb] subset: gosubset_prok synonym: "kanamycin acetyltransferase activity" NARROW [] xref: GO:0034069 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0005514 name: aminoglycoside 1-N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring." [GOC:cb] xref: GO:0034070 is_a: CCO:F0005513 ! aminoglycoside N-acetyltransferase activity [Term] id: CCO:F0005515 name: aminoglycoside phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside." [GOC:cb, GOC:mah] subset: gosubset_prok synonym: "aminoglycoside kinase activity" EXACT [] xref: EC:2.7.1.119 xref: GO:0034071 xref: MetaCyc:HYGROMYCIN-B-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0005516 name: squalene cyclase activity namespace: molecular_function def: "Catalysis of the reaction: squalene = triterpene." [GOC:cb, PMID:18033581] xref: GO:0034072 is_a: CCO:F0002427 ! cyclase activity [Term] id: CCO:F0005517 name: tetrahymanol cyclase activity namespace: molecular_function def: "Catalysis of the reaction: squalene = tetrahymanol." [ChEBI:9493, GOC:cb, PMID:18033581] xref: GO:0034073 is_a: CCO:F0005516 ! squalene cyclase activity [Term] id: CCO:F0005518 name: marneral synthase activity namespace: molecular_function def: "Catalysis of the reaction: oxidosqualene = marneral." [GOC:cb, http://www.wiley-vch.de/contents/jc_2002/2006/z503420_s.pdf, PMID:16425307, PMID:18033581] xref: GO:0034074 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0005519 name: arabidiol synthase activity namespace: molecular_function def: "Catalysis of the reaction: oxidosqualene + H2O= arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol)." [GOC:cb, PMID:16774269, PMID:17474751] xref: GO:0034075 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0005520 name: cucurbitadienol synthase activity namespace: molecular_function def: "Catalysis of the reaction: oxidosqualene = cucurbitadienol." [GOC:cb, http:/beta.uniprot.org/uniprot/Q6BE24, PMID:18033581] xref: GO:0034076 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0005521 name: steryl deacetylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol." [GOC:rb, PMID:18034159] synonym: "sterol deacetylase activity" EXACT [] xref: GO:0034084 is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0005522 name: L-vinylglycine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-vinylglutamate + H2O = alpha-ketobutryrate + NH3." [GOC:ecd, PMID:11470512] comment: Note that this function was formerly EC:4.1.99.4. subset: gosubset_prok synonym: "L-VG deaminase activity" EXACT [EC:3.5.99.7] xref: EC:3.5.99.7 xref: GO:0034100 xref: MetaCyc:4.1.99.4-RXN xref: UM-BBD_enzymeID:e0274 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0005523 name: apolipoprotein binding namespace: molecular_function def: "Interacting selectively with an apolipoprotein, the protein component of a lipoprotein complex." [GOC:rl] xref: GO:0034185 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005524 name: apolipoprotein A-I binding namespace: molecular_function def: "Interacting selectively with apolipoprotein A-I." [GOC:rl] xref: GO:0034186 is_a: CCO:F0005523 ! apolipoprotein binding [Term] id: CCO:F0005525 name: apolipoprotein E binding namespace: molecular_function def: "Interacting selectively with apolipoprotein E." [GOC:rl] xref: GO:0034187 is_a: CCO:F0005523 ! apolipoprotein binding [Term] id: CCO:F0005526 name: apolipoprotein A-I receptor activity namespace: molecular_function def: "Combining with apolipoprotein A-I to initiate a change in cell activity." [GOC:rl] xref: GO:0034188 is_a: CCO:F0004349 ! apolipoprotein receptor activity is_a: CCO:F0005524 ! apolipoprotein A-I binding [Term] id: CCO:F0005527 name: very-low-density lipoprotein binding namespace: molecular_function def: "Interacting selectively with very-low-density lipoprotein, one of the classes of lipoproteins found in blood plasma in many animals." [GOC:mah] subset: gosubset_prok synonym: "VLDL binding" EXACT [] xref: GO:0034189 is_a: CCO:F0001687 ! lipoprotein binding [Term] id: CCO:F0005528 name: apolipoprotein receptor binding namespace: molecular_function def: "Interacting selectively with an apolipoprotein receptor." [GOC:rl] xref: GO:0034190 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005529 name: apolipoprotein A-I receptor binding namespace: molecular_function def: "Interacting selectively with an apolipoprotein A-I receptor." [GOC:rl] xref: GO:0034191 is_a: CCO:F0005528 ! apolipoprotein receptor binding [Term] id: CCO:F0005530 name: D-heptose 1,7-bisphosphate phosphatase namespace: molecular_function def: "Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate." [MetaCyc:RXN0-4361, PMID:11279237] xref: GO:0034200 xref: MetaCyc:RXN0-4361 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005531 name: glycolipid-translocating activity namespace: molecular_function def: "Catalysis of the movement of glycolipids from one membrane face to the other ('flippase' activity)." [GOC:krc, PMID:11807558] synonym: "flippase activity" BROAD [] xref: GO:0034202 is_a: CCO:F0003557 ! glycolipid transporter activity [Term] id: CCO:F0005532 name: GTP-dependent protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of GTP." [GOC:ecd, PMID:17200152] xref: EC:2.7.11.- xref: GO:0034211 xref: Reactome:13522 is_a: CCO:F0001045 ! protein serine/threonine kinase activity [Term] id: CCO:F0005533 name: peptide N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide." [GOC:mah] subset: gosubset_prok xref: GO:0034212 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0005534 name: thiamin:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamin(out) + H+(out) = thiamin(in) + H+(in)." [GOC:mah] synonym: "thiamin:proton symporter activity" EXACT [] synonym: "thiamine:hydrogen symporter activity" EXACT [] synonym: "thiamine:proton symporter activity" EXACT [] xref: GO:0034215 is_a: CCO:F0002744 ! solute:hydrogen symporter activity is_a: CCO:F0002824 ! thiamin uptake transmembrane transporter activity [Term] id: CCO:F0005535 name: high-affinity thiamin:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamin(out) + H+(out) = thiamin(in) + H+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:mah] synonym: "high affinity thiamin:hydrogen symporter activity" EXACT [] synonym: "high-affinity thiamin:proton symporter activity" EXACT [] synonym: "high-affinity thiamine:hydrogen symporter activity" EXACT [] synonym: "high-affinity thiamine:proton symporter activity" EXACT [] xref: GO:0034216 is_a: CCO:F0005534 ! thiamin:hydrogen symporter activity [Term] id: CCO:F0005536 name: ethanolamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ethanolamine from one side of the membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine." [GOC:rn, PMID:3514579] subset: gosubset_prok synonym: "2-aminoethanol transmembrane transporter activity" EXACT [] synonym: "ethanolamine permease activity" EXACT [] synonym: "monoethanolamine transmembrane transporter activity" EXACT [] xref: GO:0034228 is_a: CCO:F0001529 ! amine transmembrane transporter activity [Term] id: CCO:F0005537 name: GPI anchor binding namespace: molecular_function def: "Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes." [GOC:vw] comment: Note that this term should be used to annotate gene products that interact non-covalently with GPI anchors, and not proteins that have GPI anchors covalently attached. synonym: "glycosylphosphatidylinositol binding" EXACT [] xref: GO:0034235 is_a: CCO:F0005562 ! phosphoinositide binding [Term] id: CCO:F0005538 name: protein kinase A catalytic subunit binding namespace: molecular_function def: "Interacting selectively with one or both of the catalytic subunits of protein kinase A." [GOC:mah] synonym: "PKA catalytic subunit binding" EXACT [] xref: GO:0034236 is_a: CCO:F0004210 ! protein kinase binding is_a: CCO:F0008036 ! protein kinase A binding [Term] id: CCO:F0005539 name: protein kinase A regulatory subunit binding namespace: molecular_function def: "Interacting selectively with one or both of the regulatory subunits of protein kinase A." [GOC:mah] synonym: "PKA regulatory subunit binding" EXACT [] synonym: "protein kinase A anchoring activity" RELATED [] xref: GO:0034237 is_a: CCO:F0008036 ! protein kinase A binding [Term] id: CCO:F0005540 name: mitochondrial transcription initiation factor activity namespace: molecular_function def: "A transcription factor activity that confers promoter specificity upon mitochondrial RNA polymerase, in a manner analogous to eubacterial sigma factors." [GOC:mah] synonym: "mitochondrial polymerase transcription factor activity" EXACT [] synonym: "mitochondrial transcription factor activity" RELATED [] xref: GO:0034246 is_a: CCO:F0003499 ! transcription initiation factor activity [Term] id: CCO:F0005541 name: chlorophyll(ide) b reductase activity namespace: molecular_function def: "Catalysis of the reaction: 71-hydroxychlorophyllide a + NAD(P)+ = chlorophyllide b + NAD(P)H + H+." [EC:1.1.1.294, MetaCyc:RXN-7678] synonym: "Chl b reductase activity" EXACT [] synonym: "chlorophyll b reductase activity" EXACT [] synonym: "chlorophyllide b reductase activity" EXACT [] xref: EC:1.1.1.294 xref: GO:0034256 xref: MetaCyc:RXN-7678 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005542 name: nicotinamide riboside transporter activity namespace: molecular_function def: "Catalysis of the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other." [GOC:se] xref: GO:0034257 is_a: CCO:F0001567 ! nucleoside transmembrane transporter activity [Term] id: CCO:F0005543 name: ent-cassa-12,15-diene synthase activity namespace: molecular_function def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate." [MetaCyc:RXN-4881] xref: GO:0034277 xref: MetaCyc:RXN-4881 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005544 name: stemar-13-ene synthase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-syn-copalyl diphosphate = stemar-13-ene + diphosphate." [MetaCyc:RXN-4882] xref: GO:0034278 xref: MetaCyc:RXN-4882 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005545 name: syn-pimara-7,15-diene synthase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-syn-copalyl diphosphate = (-)-9-beta-pimara-7,15-diene + diphosphate." [MetaCyc:RXN-4883] xref: GO:0034279 xref: MetaCyc:RXN-4883 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005546 name: ent-sandaracopimaradiene synthase activity namespace: molecular_function def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimaradiene + diphosphate." [MetaCyc:RXN-4884] synonym: "ent-pimaradiene synthase activity" BROAD [] xref: GO:0034280 xref: MetaCyc:RXN-4884 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005547 name: ent-isokaurene synthase activity namespace: molecular_function def: "Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate." [PMID:17141283] xref: GO:0034281 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005548 name: ent-pimara-8(14),15-diene synthase activity namespace: molecular_function def: "Catalysis of the reaction: ent-copalyl diphosphate = ent- pimara-8(14),15-diene + diphosphate." [PMID:17141283] synonym: "ent-pimaradiene synthase activity" BROAD [] xref: GO:0034282 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005549 name: syn-stemod-13(17)-ene synthase activity namespace: molecular_function def: "Catalysis of the reaction: syn-copalyl diphosphate = stemod-13(17)-ene + diphosphate." [PMID:17141283] synonym: "exo-stemodene synthase activity" EXACT [] synonym: "stemod-13(17)-ene synthase activity" EXACT [] synonym: "stemodene synthase activity" EXACT [] synonym: "syn-stemodene synthase activity" EXACT [] xref: GO:0034283 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0005550 name: holin activity namespace: molecular_function def: "Catalysis of the temporally-regulated formation of a transmembrane protein hole that directly or indirectly allows murein hydrolyases to access their cell wall substrate." [GOC:jh2, PMID:1406491] xref: GO:0034290 is_a: CCO:F0002725 ! channel activity [Term] id: CCO:F0005551 name: canonical holin activity namespace: molecular_function def: "Catalysis of the temporally-regulated formation of a non-specific transmembrane protein hole that allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell." [GOC:jh2, GOC:mah, PMID:1406491] xref: GO:0034291 is_a: CCO:F0005550 ! holin activity [Term] id: CCO:F0005552 name: pinholin activity namespace: molecular_function def: "Catalysis of the temporally-regulated formation of a transmembrane protein hole that allows the passage of ions, causing a lethal, irreversible depolarization of the cell membrane." [GOC:jh2, GOC:mah, PMID:1406491] xref: GO:0034292 is_a: CCO:F0005550 ! holin activity [Term] id: CCO:F0005553 name: phosphoinositide 3-kinase activity namespace: molecular_function def: "Catalysis of the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring to generate the 3-phosphoinositides: phosphatidylinositol-3-phosphate [PI(3)P], phosphatidylinositol-3,4-bisphosphate [PI(3,4)P2] and phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3]." [GOC:bf, PMID:10209156, PMID:9255069] xref: EC:2.7.1.- xref: GO:0035004 is_a: CCO:F0000204 ! lipid kinase activity is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0005554 name: phosphatidylinositol-4-phosphate 3-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate." [EC:2.7.1.154, GOC:bf] synonym: "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase activity" EXACT [EC:2.7.1.154] synonym: "C2-domain-containing phosphoinositide 3-kinase activity" NARROW [EC:2.7.1.154] synonym: "phosphatidylinositol 3-kinase activity, class I" NARROW [] synonym: "phosphatidylinositol 3-kinase activity, class II" NARROW [] synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" NARROW [] synonym: "type II phosphoinositide 3-kinase activity" RELATED [EC:2.7.1.154] xref: EC:2.7.1.154 xref: GO:0035005 xref: MetaCyc:2.7.1.154-RXN is_a: CCO:F0003116 ! phosphatidylinositol phosphate kinase activity is_a: CCO:F0005553 ! phosphoinositide 3-kinase activity [Term] id: CCO:F0005555 name: myosuppressin receptor activity namespace: molecular_function def: "Combining with the peptide myosuppressin to initiate a change in cell activity." [GOC:bf] xref: GO:0035013 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0005556 name: phosphoinositide 3-kinase regulator activity namespace: molecular_function def: "Modulates the activity of any of the phosphoinositide 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates." [GOC:bf, PMID:9255069] comment: See also the molecular function term 'phosphoinositide 3-kinase activity ; GO:0035004'. synonym: "PI3K regulator activity" EXACT [] xref: GO:0035014 is_a: CCO:F0004130 ! kinase regulator activity [Term] id: CCO:F0005557 name: histone deacetylase regulator activity namespace: molecular_function def: "Modulates the activity of histone deacetylase." [GOC:bf] comment: See also the molecular function term 'histone deacetylase activity ; GO:0004407'. xref: GO:0035033 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0005558 name: histone acetyltransferase regulator activity namespace: molecular_function def: "Modulates the activity of histone acetyltransferase." [GOC:bf] comment: See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'. synonym: "histone acetylase regulator activity" EXACT [] xref: GO:0035034 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0005559 name: histone acetyltransferase binding namespace: molecular_function def: "Interacting selectively with the enzyme histone acetyltransferase." [GOC:bf] synonym: "histone acetylase binding" EXACT [] xref: GO:0035035 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0005560 name: juvenile hormone acid methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to juvenile hormone acid." [GOC:bf] xref: GO:0035049 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005561 name: methylated histone residue binding namespace: molecular_function def: "Interacting selectively with a methylated residue on a histone protein. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf, PMID:14585615] xref: GO:0035064 is_a: CCO:F0005669 ! histone binding [Term] id: CCO:F0005562 name: phosphoinositide binding namespace: molecular_function def: "Interacting selectively with any inositol-containing glycerophospholipid." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0035091 is_a: CCO:F0001666 ! phospholipid binding [Term] id: CCO:F0005563 name: ecdysone binding namespace: molecular_function def: "Interacting selectively with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0582227089] xref: GO:0035100 is_a: CCO:F0001634 ! steroid binding is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0005564 name: histone kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf] xref: GO:0035173 is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0005565 name: histone serine kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf] synonym: "histone-serine kinase activity" EXACT [] xref: GO:0035174 is_a: CCO:F0001045 ! protein serine/threonine kinase activity is_a: CCO:F0005564 ! histone kinase activity [Term] id: CCO:F0005566 name: histone serine kinase activity (H3-S10 specific) namespace: molecular_function def: "Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3." [GOC:bf, PMID:15041176] synonym: "histone-serine kinase activity (H3-S10 specific)" EXACT [] xref: GO:0035175 is_a: CCO:F0005565 ! histone serine kinase activity [Term] id: CCO:F0005567 name: histone threonine kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes." [GOC:bf] synonym: "histone-threonine kinase activity" EXACT [] xref: GO:0035184 is_a: CCO:F0001045 ! protein serine/threonine kinase activity is_a: CCO:F0005564 ! histone kinase activity [Term] id: CCO:F0005568 name: siRNA binding namespace: molecular_function def: "Interacting selectively with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme." [PMID:15066275, PMID:15066283] synonym: "small interfering RNA binding" EXACT [] xref: GO:0035197 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0005569 name: miRNA binding namespace: molecular_function def: "Interacting selectively with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes." [PMID:15066283] synonym: "microRNA binding" EXACT [] xref: GO:0035198 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0005570 name: glutamate-cysteine ligase catalytic subunit binding namespace: molecular_function def: "Interacting selectively with the catalytic subunit of glutamate-cysteine ligase." [PMID:12954617] xref: GO:0035226 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0005571 name: proctolin receptor activity namespace: molecular_function def: "Combining with the neuropeptide proctolin, to initiate a change in cell activity." [GOC:bf] xref: GO:0035236 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0005572 name: corazonin receptor activity namespace: molecular_function def: "Combining with the neuropeptide corazonin to initiate a change in cell activity." [GOC:bf] xref: GO:0035237 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0005573 name: dopamine binding namespace: molecular_function def: "Interacting selectively with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0035240 is_a: CCO:F0005633 ! neurotransmitter binding [Term] id: CCO:F0005574 name: protein-arginine omega-N monomethyltransferase activity namespace: molecular_function def: "Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue." [PMID:14705965, RESID:AA0069] xref: GO:0035241 xref: RESID:AA0069 is_a: CCO:F0003096 ! protein-arginine N-methyltransferase activity [Term] id: CCO:F0005575 name: protein-arginine omega-N asymmetric methyltransferase activity namespace: molecular_function def: "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues." [PMID:14705965, RESID:AA0068, RESID:AA0069] comment: Note that type I protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242'. xref: GO:0035242 xref: RESID:AA0068 xref: RESID:AA0069 is_a: CCO:F0003096 ! protein-arginine N-methyltransferase activity [Term] id: CCO:F0005576 name: protein-arginine omega-N symmetric methyltransferase activity namespace: molecular_function def: "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues." [PMID:14705965, RESID:AA0067, RESID:AA0069] comment: Note that type II protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243'. xref: GO:0035243 xref: RESID:AA0067 xref: RESID:AA0069 is_a: CCO:F0003096 ! protein-arginine N-methyltransferase activity [Term] id: CCO:F0005577 name: peptidyl-arginine C-methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein." [GOC:bf] xref: GO:0035244 is_a: CCO:F0001756 ! C-methyltransferase activity is_a: CCO:F0001813 ! protein methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005578 name: alpha-1,4-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage." [PMID:15130086] synonym: "alpha-1,4-GalNAc transferase activity" EXACT [] xref: GO:0035248 is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0005579 name: UDP-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule." [http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html] subset: gosubset_prok xref: GO:0035250 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0005580 name: UDP-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule." [http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html] subset: gosubset_prok xref: GO:0035251 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005581 name: UDP-xylosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule." [http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html] xref: GO:0035252 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0005645 ! xylosyltransferase activity [Term] id: CCO:F0005582 name: glutamate receptor binding namespace: molecular_function def: "Interacting selectively with a glutamate receptor." [GOC:bf] xref: GO:0035254 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005583 name: ionotropic glutamate receptor binding namespace: molecular_function def: "Interacting selectively with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0035255 is_a: CCO:F0005582 ! glutamate receptor binding [Term] id: CCO:F0005584 name: metabotropic glutatmate receptor binding namespace: molecular_function def: "Interacting selectively with a metabotropic glutamate receptor. Metabotropic glutamate receptors are G-protein coupled receptors that bind glutamate and exert an effect through the regulation of enzyme activity." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:9069287] xref: GO:0035256 is_a: CCO:F0000196 ! G-protein-coupled receptor binding is_a: CCO:F0005582 ! glutamate receptor binding [Term] id: CCO:F0005585 name: nuclear hormone receptor binding namespace: molecular_function def: "Interacting selectively with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell." [GOC:bf] xref: GO:0035257 is_a: CCO:F0008109 ! hormone receptor binding [Term] id: CCO:F0005586 name: steroid hormone receptor binding namespace: molecular_function def: "Interacting selectively with a steroid hormone receptor." [GOC:bf] xref: GO:0035258 is_a: CCO:F0005585 ! nuclear hormone receptor binding [Term] id: CCO:F0005587 name: glucocorticoid receptor binding namespace: molecular_function def: "Interacting selectively with a glucocorticoid receptor." [GOC:bf] xref: GO:0035259 is_a: CCO:F0005586 ! steroid hormone receptor binding [Term] id: CCO:F0005588 name: phthalate binding namespace: molecular_function def: "Interacting selectively with a phthalate, any ester or salt of phthalic acid." [http://umbbd.ahc.umn.edu/pth/pth_map.html] subset: goslim_pir subset: gosubset_prok xref: GO:0035273 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005589 name: diphenyl phthalate binding namespace: molecular_function def: "Interacting selectively with diphenyl phthalate, C(20)H(14)O(4)." [http://www.sigmaaldrich.com] synonym: "DPP binding" EXACT [] xref: GO:0035274 is_a: CCO:F0005588 ! phthalate binding [Term] id: CCO:F0005590 name: dibutyl phthalate binding namespace: molecular_function def: "Interacting selectively with dibutyl phthalate, C(16)H(22)O(4)." [http://www.sigmaaldrich.com] synonym: "DBP binding" EXACT [] synonym: "phthalic acid dibutyl ester binding" EXACT [] xref: GO:0035275 is_a: CCO:F0005588 ! phthalate binding [Term] id: CCO:F0005591 name: ethanol binding namespace: molecular_function def: "Interacting selectively with ethanol, CH(3)-CH(2)-OH." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0035276 is_a: CCO:F0005812 ! alcohol binding [Term] id: CCO:F0005592 name: inositol pentakisphosphate 2-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol hexakisphosphate." [EC:2.7.1.158] synonym: "ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase activity" EXACT [EC:2.7.1.158] synonym: "Gsl1p" RELATED [EC:2.7.1.158] synonym: "inositol 1,3,4,5,6-pentakisphosphate 2-kinase activity" EXACT [EC:2.7.1.158] synonym: "inositol polyphosphate kinase activity" EXACT [EC:2.7.1.158] synonym: "inositol-pentakisphosphate 2-kinase activity" EXACT [EC:2.7.1.158] synonym: "Ins(1,3,4,5,6)P5 2-kinase activity" EXACT [EC:2.7.1.158] synonym: "IP5 2-kinase activity" EXACT [EC:2.7.1.158] synonym: "Ipk1p" RELATED [EC:2.7.1.158] xref: EC:2.7.1.158 xref: GO:0035299 is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0005593 name: inositol-1,3,4-trisphosphate 5/6-kinase activity namespace: molecular_function def: "Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate." [EC:2.7.1.159, PMID:9126335] synonym: "ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.159] synonym: "inositol 1,3,4-trisphosphate 5-kinase activity" NARROW [] synonym: "inositol 1,3,4-trisphosphate 6-kinase activity" NARROW [] synonym: "inositol trisphosphate 5/6-kinase activity" EXACT [EC:2.7.1.159] synonym: "Ins(1,3,4)P3 5/6-kinase activity" EXACT [EC:2.7.1.159] synonym: "IP56K" RELATED [EC:2.7.1.159] xref: EC:2.7.1.159 xref: GO:0035300 xref: MetaCyc:2.7.1.133-RXN is_a: CCO:F0008191 ! inositol trisphosphate kinase activity [Term] id: CCO:F0005594 name: ecdysteroid 25-hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:15350618] comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol). xref: GO:0035302 is_a: CCO:F0001866 ! steroid hydroxylase activity [Term] id: CCO:F0005595 name: 5'-3' exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule." [ISBN:0198547684] xref: GO:0035312 is_a: CCO:F0001876 ! 5'-3' exonuclease activity is_a: CCO:F0003453 ! exodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005596 name: interleukin-18 binding namespace: molecular_function def: "Interacting selectively with interleukin-18." [GOC:jl] synonym: "IL-18 binding" EXACT [] xref: GO:0042007 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0005597 name: interleukin-18 receptor activity namespace: molecular_function def: "Combining with interleukin-18 to initiate a change in cell activity." [GOC:jl] synonym: "IL-18R" EXACT [] xref: GO:0042008 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0005596 ! interleukin-18 binding [Term] id: CCO:F0005598 name: interleukin-15 binding namespace: molecular_function def: "Interacting selectively with interleukin-15." [GOC:jl] synonym: "IL-15 binding" EXACT [] xref: GO:0042009 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0005599 name: interleukin-15 receptor activity namespace: molecular_function def: "Combining with interleukin-15 to initiate a change in cell activity." [GOC:jl] synonym: "IL-15R" EXACT [] xref: GO:0042010 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0005598 ! interleukin-15 binding [Term] id: CCO:F0005600 name: interleukin-16 binding namespace: molecular_function def: "Interacting selectively with interleukin-16." [GOC:jl] synonym: "IL-16 binding" EXACT [] xref: GO:0042011 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0005601 name: interleukin-16 receptor activity namespace: molecular_function def: "Combining with interleukin-16 to initiate a change in cell activity." [GOC:jl] synonym: "IL-16R" EXACT [] xref: GO:0042012 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0005600 ! interleukin-16 binding [Term] id: CCO:F0005602 name: interleukin-19 binding namespace: molecular_function def: "Interacting selectively with interleukin-19." [GOC:jl] synonym: "IL-19 binding" EXACT [] xref: GO:0042013 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0005603 name: interleukin-19 receptor activity namespace: molecular_function def: "Combining with interleukin-19 to initiate a change in cell activity." [GOC:jl] synonym: "IL-19R" EXACT [] xref: GO:0042014 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0005602 ! interleukin-19 binding [Term] id: CCO:F0005604 name: interleukin-20 binding namespace: molecular_function def: "Interacting selectively with interleukin-20." [GOC:jl] synonym: "IL-20 binding" EXACT [] xref: GO:0042015 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0005605 name: interleukin-20 receptor activity namespace: molecular_function def: "Combining with interleukin-20 to initiate a change in cell activity." [GOC:jl] synonym: "IL-20R" EXACT [] xref: GO:0042016 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0005604 ! interleukin-20 binding [Term] id: CCO:F0005606 name: interleukin-22 binding namespace: molecular_function def: "Interacting selectively with interleukin-22." [GOC:jl] synonym: "IL-22 binding" EXACT [] xref: GO:0042017 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0005607 name: interleukin-22 receptor activity namespace: molecular_function def: "Combining with interleukin-22 to initiate a change in cell activity." [GOC:jl] synonym: "IL-22R" EXACT [] xref: GO:0042018 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0005606 ! interleukin-22 binding [Term] id: CCO:F0005608 name: interleukin-23 binding namespace: molecular_function def: "Interacting selectively with interleukin-23." [GOC:jl] synonym: "IL-23 binding" EXACT [] xref: GO:0042019 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0005609 name: interleukin-23 receptor activity namespace: molecular_function def: "Combining with interleukin-23 to initiate a change in cell activity." [GOC:jl] synonym: "IL-23R" EXACT [] xref: GO:0042020 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0005608 ! interleukin-23 binding [Term] id: CCO:F0005610 name: granulocyte macrophage colony-stimulating factor complex binding namespace: molecular_function def: "Interacting selectively with the granulocyte macrophage colony-stimulating factor complex." [GOC:ai] synonym: "GM-CSF complex binding" EXACT [] synonym: "GMC-SF complex binding" EXACT [] xref: GO:0042021 is_a: CCO:F0004221 ! cytokine binding [Term] id: CCO:F0005611 name: juglone-sensitive peptidyl-prolyl cis-trans isomerase activity namespace: molecular_function synonym: "juglone-sensitive cis-trans proline isomerase activity" EXACT [] xref: EC:5.2.1.- xref: GO:0042028 is_a: CCO:F0000319 ! peptidyl-prolyl cis-trans isomerase activity [Term] id: CCO:F0005612 name: fibrolase activity namespace: molecular_function def: "Catalysis of the cleavage of 14-Ala-Leu-15 in insulin B chain and cleavage of 413-Lys-Leu-414 in alpha chain of fibrinogen." [EC:3.4.24.72, PMID:7725320] synonym: "Agkistrodon contortrix contortrix metalloproteinase activity" NARROW [EC:3.4.24.72] synonym: "Agkistrodon contortrix contortrix venom metalloproteinase activity" NARROW [EC:3.4.24.72] synonym: "fibrinolytic proteinase activity" EXACT [EC:3.4.24.72] xref: EC:3.4.24.72 xref: GO:0042029 xref: MetaCyc:3.4.24.72-RXN is_a: CCO:F0000676 ! metalloendopeptidase activity [Term] id: CCO:F0005613 name: ATPase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate." [GOC:jl] synonym: "adenosinetriphosphatase inhibitor" EXACT [] xref: GO:0042030 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0005614 name: angiotensin-converting enzyme inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of angiotensin-converting enzyme, thereby preventing the synthesis of angiotensin II from its precursor, angiotensin I." [GOC:jl] synonym: "ACE inhibitor" EXACT [] synonym: "peptidyl dipeptidase A inhibitor" EXACT [] xref: GO:0042031 is_a: CCO:F0004441 ! protease inhibitor activity [Term] id: CCO:F0005615 name: neurexin binding namespace: molecular_function def: "Interacting selectively with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals." [http://cancerweb.ncl.ac.uk/] synonym: "neuroligin" RELATED [] xref: GO:0019963 xref: GO:0042043 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005616 name: histone methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group (CH3-) to a histone." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0042054 is_a: CCO:F0001813 ! protein methyltransferase activity [Term] id: CCO:F0005617 name: chemoattractant activity namespace: molecular_function def: "Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok synonym: "attractant" BROAD [] xref: GO:0042056 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0005618 name: leucokinin receptor activity namespace: molecular_function def: "Combining with a leucokinin, any of several octapeptide hormones found in insects, to initiate a change in cell activity." [GOC:mah, PMID:2716741] xref: GO:0042071 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0005619 name: 5,10-methylenetetrahydrofolate-dependent methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate." [GOC:ai] subset: gosubset_prok xref: GO:0042083 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005620 name: 5-methyltetrahydrofolate-dependent methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate." [GOC:ai] subset: gosubset_prok xref: GO:0042084 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005621 name: 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate." [GOC:ai] subset: gosubset_prok xref: GO:0042085 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005622 name: 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin." [GOC:ai] subset: gosubset_prok xref: GO:0042086 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005623 name: glucanosyltransferase activity namespace: molecular_function def: "Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation." [GOC:jl] xref: GO:0042123 is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0005624 name: 1,3-beta-glucanosyltransferase activity namespace: molecular_function def: "Catalysis of the splitting and linkage of 1,3-beta-glucan molecules, resulting in 1,3-beta-glucan chain elongation." [GOC:jl, PMID:10809732] xref: GO:0042124 is_a: CCO:F0005623 ! glucanosyltransferase activity [Term] id: CCO:F0005625 name: thiamin phosphate phosphatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of thiamin phosphate." [PMID:197075] synonym: "thiamine phosphate phosphatase activity" EXACT [] xref: GO:0042131 is_a: CCO:F0000478 ! acid phosphatase activity [Term] id: CCO:F0005627 name: rRNA primary transcript binding namespace: molecular_function def: "Interacting selectively with an unprocessed ribosomal RNA transcript." [GOC:jl] xref: GO:0042134 is_a: CCO:F0004192 ! rRNA binding [Term] id: CCO:F0005628 name: RPTP-like protein binding namespace: molecular_function def: "Interacting selectively with proteins with similar structure/function to receptor protein tyrosine phosphatases." [GOC:jl] synonym: "receptor protein tyrosine phosphatase-like protein binding" EXACT [] xref: GO:0042153 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005629 name: zinc-mediated transcriptional activator activity namespace: molecular_function def: "Initiates or upregulates transcription in the presence of zinc." [GOC:jl] xref: GO:0042156 is_a: CCO:F0003205 ! transcription activator activity [Term] id: CCO:F0005630 name: telomeric DNA binding namespace: molecular_function def: "Interacting selectively with telomere-associated DNA, usually characterized by highly repetitive sequences." [GOC:jl, ISBN:0321000382] synonym: "telomere binding" BROAD [] xref: GO:0042162 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0005631 name: interleukin-12 beta subunit binding namespace: molecular_function def: "Interacting selectively with the beta subunit of interleukin-12." [GOC:mah] synonym: "CLMFp40 binding" EXACT [] synonym: "IL-12B binding" EXACT [] synonym: "IL-12p40 binding" EXACT [] synonym: "NKSFp40 binding" EXACT [] xref: GO:0042163 is_a: CCO:F0004236 ! interleukin-12 binding [Term] id: CCO:F0005632 name: interleukin-12 alpha subunit binding namespace: molecular_function def: "Interacting selectively with the alpha subunit of interleukin-12." [GOC:mah] synonym: "CLMFp35 binding" EXACT [] synonym: "IL-12A binding" EXACT [] synonym: "IL-12p35 binding" EXACT [] synonym: "NKSFp35 binding" EXACT [] xref: GO:0042164 is_a: CCO:F0004236 ! interleukin-12 binding [Term] id: CCO:F0005633 name: neurotransmitter binding namespace: molecular_function def: "Interacting selectively with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir xref: GO:0042165 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005634 name: acetylcholine binding namespace: molecular_function def: "Interacting selectively with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] xref: GO:0042166 is_a: CCO:F0005633 ! neurotransmitter binding is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0005635 name: SH2 domain binding namespace: molecular_function def: "Interacting selectively with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class." [GOC:go_curators, Pfam:PF00017] xref: GO:0042169 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0005636 name: lysophosphatidic acid acyltransferase activity namespace: molecular_function xref: GO:0042171 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0005637 name: cobyrinic acid a,c-diamide synthase activity namespace: molecular_function def: "Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide." [PMID:2172209] comment: Note that this enzyme does not have an EC number yet, as its activity has not been proven experimentally. May need to be moved in the future. subset: gosubset_prok synonym: "CobB" NARROW [] xref: GO:0042242 is_a: CCO:F0000778 ! glutaminase activity [Term] id: CCO:F0005638 name: neuropeptide F receptor activity namespace: molecular_function def: "Combining with neuropeptide F, an invertebrate neuropeptide thought to play a role in neuroregulation, to initiate a change in cell activity. In many species, neuropeptide F is between 36 and 39 amino acid residues terminating in a phenylalaninamide residue." [GOC:ma] xref: GO:0042263 is_a: CCO:F0001769 ! neuropeptide receptor activity [Term] id: CCO:F0005639 name: peptide binding namespace: molecular_function def: "Interacting selectively with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds." [GOC:jl] subset: goslim_pir subset: gosubset_prok xref: GO:0042277 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005640 name: nitrite reductase (cytochrome, ammonia-forming) activity namespace: molecular_function def: "Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = NO2(-) (nitrite) + 6 ferrocytochrome c + 7 H+." [EC:1.7.2.2] subset: gosubset_prok synonym: "ammonia:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.7.2.2] synonym: "cytochrome c nitrite reductase activity" EXACT [] synonym: "cytochrome c552 activity" NARROW [EC:1.7.2.2] synonym: "multiheme nitrite reductase activity" EXACT [] synonym: "nitrite reductase (cytochrome; ammonia-forming)" EXACT [EC:1.7.2.2] xref: EC:1.7.2.2 xref: GO:0042279 xref: MetaCyc:1.7.2.2-RXN is_a: CCO:F0003257 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor [Term] id: CCO:F0005641 name: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol." [UniProtKB:Q9VKX7] synonym: "dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0042281 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005642 name: hydroxymethylglutaryl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+." [EC:1.1.1.88] subset: gosubset_prok synonym: "(R)-mevalonate:NAD+ oxidoreductase (CoA-acylating)" EXACT [EC:1.1.1.88] synonym: "3-hydroxy-3-methylglutaryl coenzyme A reductase activity" EXACT [EC:1.1.1.88] synonym: "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [EC:1.1.1.88] synonym: "beta-hydroxy-beta-methylglutaryl CoA-reductase activity" BROAD [EC:1.1.1.88] synonym: "beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity" BROAD [EC:1.1.1.88] synonym: "HMG-CoA reductase activity" BROAD [EC:1.1.1.88] synonym: "hydroxymethylglutaryl coenzyme A reductase activity" BROAD [EC:1.1.1.88] synonym: "hydroxymethylglutaryl-CoA reductase (NADH) activity" EXACT [EC:1.1.1.88] xref: EC:1.1.1.88 xref: GO:0042282 xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005643 name: dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol." [UniProtKB:Q9W3V8] synonym: "dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0042283 is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0005644 name: sphingolipid delta-4 desaturase activity namespace: molecular_function def: "Catalysis of the introduction of a trans double bond between C4 and C5 of the long chain base region of a sphingolipid. Sphingolipids are composed of a long chain base (LCB) amide-linked to a very long chain fatty acid." [PMID:12417141] synonym: "delta-4 sphingolipid desaturase activity" EXACT [] xref: GO:0042284 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0005645 name: xylosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] xref: GO:0042285 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0005646 name: glutamate-1-semialdehyde 2,1-aminomutase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate." [EC:5.4.3.8] subset: gosubset_prok synonym: "(S)-4-amino-5-oxopentanoate 4,5-aminomutase activity" EXACT [EC:5.4.3.8] synonym: "glutamate-1-semialdehyde aminotransferase activity" EXACT [EC:5.4.3.8] xref: EC:5.4.3.8 xref: GO:0042286 xref: MetaCyc:GSAAMINOTRANS-RXN is_a: CCO:F0003430 ! intramolecular transferase activity, transferring amino groups [Term] id: CCO:F0005647 name: MHC protein binding namespace: molecular_function def: "Interacting selectively with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation." [GOC:jl] comment: Note that this term does not include binding to the antigen peptide bound to the MHC protein, for this also annotate to 'peptide antigen binding ; GO:0042605' or one of its children. synonym: "major histocompatibility complex binding" EXACT [] synonym: "major histocompatibility complex ligand" NARROW [] xref: GO:0042287 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005648 name: MHC class I protein binding namespace: molecular_function def: "Interacting selectively with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation." [GOC:jl] comment: Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children. synonym: "alpha-beta T cell receptor activity" RELATED [] synonym: "gamma-delta T cell receptor activity" RELATED [] synonym: "major histocompatibility complex class I binding" EXACT [] synonym: "major histocompatibility complex class I ligand" NARROW [] synonym: "T cell receptor activity" RELATED [] xref: GO:0042288 is_a: CCO:F0005647 ! MHC protein binding [Term] id: CCO:F0005649 name: MHC class II protein binding namespace: molecular_function def: "Interacting selectively with major histocompatibility complex class II molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation." [GOC:jl] comment: Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children. synonym: "major histocompatibility complex class II binding" EXACT [] synonym: "major histocompatibility complex class II ligand" NARROW [] xref: GO:0042289 is_a: CCO:F0005647 ! MHC protein binding [Term] id: CCO:F0005650 name: URM1 activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] xref: GO:0042292 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0005651 name: Hub1 activating enzyme activity namespace: molecular_function def: "Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond." [GOC:mah] xref: GO:0042293 is_a: CCO:F0002013 ! small protein activating enzyme activity [Term] id: CCO:F0005652 name: URM1 conjugating enzyme activity namespace: molecular_function def: "Catalysis of the covalent attachment of the ubiquitin-like protein URM1 to other proteins or other substrate molecules." [GOC:mah, PMID:12826404] xref: GO:0042294 is_a: CCO:F0004170 ! small conjugating protein ligase activity [Term] id: CCO:F0005654 name: lupeol synthase activity namespace: molecular_function def: "Catalysis of the cyclization of (S)-2,3-oxidosqualene to lupeol." [PMID:9883589] synonym: "oxidosqualene:lupeol cyclase activity" EXACT [PMID:18033581] xref: EC:5.4.99.- xref: GO:0042299 xref: MetaCyc:PWY-112 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0005655 name: beta-amyrin synthase activity namespace: molecular_function def: "Catalysis of the cyclization and rearrangement of 2,3-oxidosqualene into beta-amyrin." [PMID:9746369] synonym: "oxidosqualene:beta-amyrin cyclase activity" EXACT [PMID:18033581] xref: EC:5.4.99.- xref: GO:0042300 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0005656 name: phosphate binding namespace: molecular_function def: "Interacting selectively with phosphate." [GOC:jl] subset: gosubset_prok xref: GO:0042301 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005657 name: structural constituent of cuticle namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a cuticle." [GOC:jl] xref: GO:0042302 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0005658 name: bacteriochlorophyll binding namespace: molecular_function def: "Interacting selectively with bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants." [ISBN:0192800981] subset: gosubset_prok xref: GO:0042314 is_a: CCO:F0003059 ! chlorophyll binding [Term] id: CCO:F0005659 name: cytosol nonspecific dipeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids." [EC:3.4.13.18] comment: Note that this function was formerly EC:3.4.3.1, EC:3.4.3.2, EC:3.4.3.6, EC:3.4.13.1, EC:3.4.13.2, EC:3.4.13.8, EC:3.4.13.11 and EC:3.4.13.15. subset: gosubset_prok synonym: "cytosol non-specific dipeptidase activity" EXACT [EC:3.4.13.18] synonym: "diglycinase activity" EXACT [EC:3.4.13.18] synonym: "Gly-Leu hydrolase activity" EXACT [EC:3.4.13.18] synonym: "glycyl-glycine dipeptidase activity" NARROW [EC:3.4.13.18] synonym: "glycyl-L-leucine dipeptidase activity" EXACT [EC:3.4.13.18] synonym: "glycyl-L-leucine hydrolase activity" EXACT [EC:3.4.13.18] synonym: "glycyl-L-leucine peptidase activity" EXACT [EC:3.4.13.18] synonym: "glycyl-leucine dipeptidase activity" NARROW [EC:3.4.13.18] synonym: "glycylleucine dipeptide hydrolase activity" EXACT [EC:3.4.13.18] synonym: "glycylleucine hydrolase activity" EXACT [EC:3.4.13.18] synonym: "glycylleucine peptidase activity" EXACT [EC:3.4.13.18] synonym: "human cytosolic non-specific dipeptidase activity" EXACT [EC:3.4.13.18] synonym: "iminodipeptidase activity" EXACT [EC:3.4.13.18] synonym: "L-amino-acyl-L-amino-acid hydrolase activity" EXACT [EC:3.4.13.18] synonym: "L-prolylglycine dipeptidase activity" EXACT [EC:3.4.13.18] synonym: "N(2)-beta-alanylarginine dipeptidase activity" NARROW [EC:3.4.13.18] synonym: "N2-beta-alanylarginine dipeptidase activity" EXACT [EC:3.4.13.18] synonym: "non-specific dipeptidase activity" EXACT [EC:3.4.13.18] synonym: "peptidase A activity" BROAD [EC:3.4.13.18] synonym: "Pro-X dipeptidase activity" NARROW [EC:3.4.13.18] synonym: "prolinase activity" NARROW [EC:3.4.13.18] synonym: "prolyl dipeptidase activity" NARROW [EC:3.4.13.18] synonym: "prolylglycine dipeptidase activity" NARROW [EC:3.4.13.18] xref: EC:3.4.13.18 xref: GO:0042315 xref: MetaCyc:3.4.13.18-RXN is_a: CCO:F0003375 ! dipeptidase activity [Term] id: CCO:F0005660 name: hypocretin receptor binding namespace: molecular_function def: "Interacting selectively with the hypocretin receptor." [GOC:ceb, PMID:11988773] synonym: "hypocretin receptor ligand" NARROW [] synonym: "orexin receptor binding" EXACT [] synonym: "orexin receptor ligand" NARROW [] xref: GO:0042324 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0005661 name: heparan sulfate N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate." [GOC:ma] synonym: "heparan sulphate N-acetylglucosaminyltransferase activity" EXACT [] synonym: "heparin N-acetylglucosaminyltransferase activity" RELATED [] xref: GO:0042328 is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0005662 name: structural constituent of collagen and cuticulin-based cuticle namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle." [GOC:jl, GOC:mtg_sensu] synonym: "structural constituent of cuticle (sensu Nematoda)" EXACT [] xref: GO:0042329 is_a: CCO:F0005657 ! structural constituent of cuticle [Term] id: CCO:F0005663 name: guiding stereospecific synthesis activity namespace: molecular_function def: "The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis." [GOC:ma] synonym: "dirigent protein" NARROW [] xref: GO:0042349 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0005664 name: GDP-4-dehydro-D-rhamnose reductase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed." [BRENDA:1.1.1.187, EC:1.1.1.187] subset: gosubset_prok synonym: "GDP-4-keto-6-deoxy-D-mannose reductase activity" EXACT [EC:1.1.1.187] synonym: "GDP-4-keto-D-rhamnose reductase activity" EXACT [EC:1.1.1.187] synonym: "GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity" EXACT [EC:1.1.1.187] synonym: "guanosine diphosphate-4-keto-D-rhamnose reductase activity" EXACT [EC:1.1.1.187] xref: EC:1.1.1.187 xref: GO:0042356 xref: MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005665 name: chemokine receptor binding namespace: molecular_function def: "Interacting selectively with any chemokine receptor." [GOC:ai] synonym: "chemokine receptor ligand" NARROW [] xref: GO:0042379 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0005666 name: hydroxymethylbutenyl pyrophosphate reductase activity namespace: molecular_function def: "Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate." [GOC:js] comment: Note that the enzyme performing this function has only recently been characterized, and not completely (see PMID:11818558). The common and systematic names have been suggested by TIGR, who have recently compiled an HMM model for this gene (TIGR00216). The enzyme appears to catalyze the final step in the non-mevalonate terpene biosynthesis pathway. Its two products, isopentenyl pyrophosphate and dimethylallyl pyrophosphate, are apparently generated from a common intermediate formed by the enzyme. The mechanism and identity of the reductant have not yet been determined. subset: gosubset_prok synonym: "(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming)" EXACT [] xref: GO:0042380 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0005667 name: omega-3 fatty acid desaturase activity namespace: molecular_function def: "Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain." [GOC:jl, PMID:9037020] xref: EC:1.14.99.- xref: GO:0042389 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0005668 name: sphingosine-1-phosphate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate." [GOC:jl, PMID:11331102] synonym: "sphingosine-1-phosphate phosphohydrolase activity" EXACT [] synonym: "SPP phosphatase activity" EXACT [] synonym: "SPPase activity" EXACT [] xref: GO:0042392 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005669 name: histone binding namespace: molecular_function def: "Interacting selectively with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity." [GOC:jl] synonym: "histone-specific chaperone activity" RELATED [] xref: GO:0042393 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005670 name: myrcene/(E)-beta-ocimene synthase activity namespace: molecular_function def: "Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes." [GOC:cr, PMID:10700382] synonym: "myrcene/ocimene synthase activity" EXACT [] xref: EC:4.6.-.- xref: GO:0042408 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0005671 name: caffeoyl-CoA O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA." [EC:2.1.1.104] subset: gosubset_prok synonym: "caffeoyl coenzyme A methyltransferase activity" EXACT [] synonym: "caffeoyl-CoA 3-O-methyltransferase activity" EXACT [] synonym: "S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity" EXACT [EC:2.1.1.104] synonym: "trans-caffeoyl-CoA 3-O-methyltransferase activity" EXACT [EC:2.1.1.104] xref: EC:2.1.1.104 xref: GO:0042409 xref: MetaCyc:CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0005672 name: 6-carboxyhexanoate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA." [EC:6.2.1.14] subset: gosubset_prok synonym: "6-carboxyhexanoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.14] synonym: "6-carboxyhexanoyl-CoA synthetase activity" EXACT [EC:6.2.1.14] synonym: "pimeloyl-CoA synthetase activity" EXACT [EC:6.2.1.14] synonym: "pimelyl-CoA synthetase activity" EXACT [EC:6.2.1.14] xref: EC:6.2.1.14 xref: GO:0042410 xref: MetaCyc:6-CARBOXYHEXANOATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0005673 name: beta-carotene hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of both beta rings of beta-carotene to form zeaxanthine." [GOC:cr] xref: GO:0042411 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0005674 name: versicolorin reductase activity namespace: molecular_function def: "Catalysis of the reduction of versicolorin A to sterigmatocystin." [UniProtKB:P50161] xref: EC:1.1.-.- xref: GO:0042469 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0005675 name: triacylated lipoprotein binding namespace: molecular_function def: "Interacting selectively with any conjugated, water-soluble protein in which the nonprotein moiety consists of a three acyl groups." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0042497 is_a: CCO:F0001687 ! lipoprotein binding [Term] id: CCO:F0005676 name: diacylated lipoprotein binding namespace: molecular_function def: "Interacting selectively with any conjugated, water-soluble protein in which the nonprotein moiety consists of a two acyl groups." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0042498 is_a: CCO:F0001687 ! lipoprotein binding [Term] id: CCO:F0005677 name: signal peptide peptidase activity namespace: molecular_function def: "Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein." [PMID:12077416] comment: Note that this function is distinct from the 'signal peptidases' (see the molecular function term 'signal peptidase activity ; GO:0009003' and its children). Broadly, signal peptidases cleave N-terminal leader sequences from secreted or membrane proteins, thereby creating signal peptides, while signal peptide peptidases cleave the signal peptides themselves. synonym: "SPP" EXACT [] xref: EC:3.4.23.- xref: GO:0042499 is_a: CCO:F0005678 ! aspartic endopeptidase activity, intramembrane cleaving [Term] id: CCO:F0005678 name: aspartic endopeptidase activity, intramembrane cleaving namespace: molecular_function def: "Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides, occurring within the plasma membrane." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: Note that although GO generally avoids the use of localization information in terms, in this case an exception was made. This is because the fact that the cleavage occurs within the membrane is integral to its function, as it is the only thing that distinguishes this group from other aspartic endopeptidases. xref: EC:3.4.23.- xref: GO:0042500 is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0005679 name: eukaryotic elongation factor-2 kinase regulator activity namespace: molecular_function def: "Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase." [GOC:jl, PMID:11904175] synonym: "eEF-2 kinase regulator" EXACT [] xref: EC:2.7.1.- xref: GO:0042556 is_a: CCO:F0004204 ! protein kinase regulator activity [Term] id: CCO:F0005680 name: eukaryotic elongation factor-2 kinase activator activity namespace: molecular_function def: "Increases the activity of the enzyme eukaryotic elongation factor-2 kinase." [GOC:jl, PMID:11904175] synonym: "eEF-2 kinase activator" EXACT [] xref: EC:2.7.1.- xref: GO:0042557 is_a: CCO:F0004382 ! protein kinase activator activity is_a: CCO:F0005679 ! eukaryotic elongation factor-2 kinase regulator activity [Term] id: CCO:F0005681 name: alpha-amyrin synthase activity namespace: molecular_function def: "Catalysis of the cyclization and rearrangement of 2,3-oxidosqualene into alpha-amyrin." [GOC:jl, PMID:10848960] xref: GO:0042561 xref: MetaCyc:PWY-5377 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0005682 name: hormone binding namespace: molecular_function def: "Interacting selectively with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: goslim_pir xref: GO:0042562 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005683 name: aspartyl aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate." [EC:3.4.11.21] subset: gosubset_prok xref: EC:3.4.11.21 xref: GO:0042576 xref: MetaCyc:3.4.11.21-RXN is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0005684 name: lipid phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate." [GOC:jl] xref: GO:0042577 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005685 name: phosphoric ester hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3." [GOC:jl] subset: gosubset_prok xref: EC:3.1.-.- xref: GO:0042578 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0005686 name: peptide deformylase activity namespace: molecular_function def: "Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide." [EC:3.5.1.88, GOC:jl] subset: gosubset_prok synonym: "formyl-L-methionyl peptide amidohydrolase activity" EXACT [EC:3.5.1.88] synonym: "PDF activity" EXACT [EC:3.5.1.88] synonym: "polypeptide deformylase activity" EXACT [EC:3.5.1.88] xref: EC:3.5.1.88 xref: GO:0042586 xref: MetaCyc:3.5.1.88-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005687 name: flavin reductase activity namespace: molecular_function def: "Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + H+." [EC:1.5.1.30] subset: gosubset_prok synonym: "FMN reductase (NADPH) activity" EXACT [EC:1.5.1.30] synonym: "NADPH dehydrogenase (flavin) activity" EXACT [EC:1.5.1.30] synonym: "NADPH-dependent FMN reductase activity" EXACT [EC:1.5.1.30] synonym: "NADPH-flavin oxidoreductase activity" EXACT [] synonym: "NADPH-flavin reductase activity" EXACT [EC:1.5.1.30] synonym: "NADPH-FMN reductase activity" EXACT [EC:1.5.1.30] synonym: "NADPH-specific FMN reductase activity" EXACT [EC:1.5.1.30] synonym: "NADPH2 dehydrogenase (flavin)" EXACT [EC:1.5.1.30] synonym: "NADPH2:riboflavin oxidoreductase activity" EXACT [EC:1.5.1.30] synonym: "NADPH:flavin oxidoreductase activity" EXACT [EC:1.5.1.30] synonym: "NADPH:riboflavin oxidoreductase activity" EXACT [EC:1.5.1.30] synonym: "reduced-riboflavin:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.30] synonym: "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.5.1.30] synonym: "riboflavin mononucleotide reductase activity" BROAD [EC:1.5.1.30] synonym: "riboflavine mononucleotide reductase activity" BROAD [EC:1.5.1.30] xref: EC:1.5.1.30 xref: GO:0042602 xref: MetaCyc:NADPH-DEHYDROGENASE-(FLAVIN)-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005688 name: peptide antigen binding namespace: molecular_function def: "Interacting selectively with an antigen peptide, a fragment of a foreign protein derived by proteolysis within the cell." [GOC:jl] comment: Note that this term can be used to describe binding to the peptide expressed by an MHC molecule. xref: GO:0042605 is_a: CCO:F0000342 ! antigen binding is_a: CCO:F0005639 ! peptide binding [Term] id: CCO:F0005689 name: endogenous peptide antigen binding namespace: molecular_function def: "Interacting selectively with an antigen peptide, a fragment of an endogenous foreign protein, derived by proteolysis within the cell." [GOC:jl] comment: Note that this term can be used to describe binding to the peptide expressed by an MHC molecule. xref: GO:0042606 is_a: CCO:F0005688 ! peptide antigen binding [Term] id: CCO:F0005690 name: exogenous peptide antigen binding namespace: molecular_function def: "Interacting selectively with an antigen peptide, a fragment of an exogenous foreign protein derived by endocytosis of the protein and proteolysis within the cell." [GOC:jl] comment: Note that this term can be used to describe binding to the peptide expressed by an MHC molecule. synonym: "alpha-beta T cell receptor activity" RELATED [] synonym: "gamma-delta T cell receptor activity" RELATED [] synonym: "T cell receptor activity" RELATED [] xref: GO:0042607 is_a: CCO:F0005688 ! peptide antigen binding [Term] id: CCO:F0005691 name: T cell receptor binding namespace: molecular_function def: "Interacting selectively with a T cell receptor, the antigen-recognizing receptor on the surface of T cells." [GOC:jl, http://cancerweb.ncl.ac.uk/] synonym: "T lymphocyte receptor binding" EXACT [] synonym: "T-cell receptor binding" EXACT [] synonym: "T-lymphocyte receptor binding" EXACT [] synonym: "TCR binding" EXACT [] xref: GO:0042608 is_a: CCO:F0001407 ! receptor binding is_a: CCO:F0004983 ! protein complex binding [Term] id: CCO:F0005692 name: CD4 receptor binding namespace: molecular_function def: "Interacting selectively with a CD4, a receptor found on the surface of T cells, monocytes and macrophages." [GOC:jl, MeSH:D015704] xref: GO:0042609 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005693 name: CD8 receptor binding namespace: molecular_function def: "Interacting selectively with a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes." [GOC:jl, MeSH:D016827] xref: GO:0042610 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005694 name: CD70 receptor binding namespace: molecular_function def: "Interacting selectively with a CD70, a receptor found on the surface of most activated B cells and some activated T cells." [GOC:jl, ISBN:0120781859] synonym: "CD27 receptor activity" RELATED [] synonym: "CD27L binding" EXACT [] xref: GO:0042614 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005695 name: CD154 receptor binding namespace: molecular_function def: "Interacting selectively with CD154, a receptor found on the surface of some activated lymphocytes." [GOC:jl, ISBN:0120781859] synonym: "CD40 receptor activity" RELATED [] synonym: "CD40L binding" EXACT [] xref: GO:0042615 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005696 name: ATPase activity, coupled namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (polypeptide-unfolding)" NARROW [EC:3.6.4.9] synonym: "chaperonin" RELATED [EC:3.6.4.9] synonym: "chaperonin ATPase activity" RELATED [] synonym: "non-chaperonin molecular chaperone ATPase activity" RELATED [] synonym: "nucleoplasmin ATPase activity" RELATED [] synonym: "peroxisome-assembly ATPase activity" RELATED [] xref: GO:0042623 is_a: CCO:F0003445 ! ATPase activity [Term] id: CCO:F0005697 name: ATPase activity, uncoupled namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; not directly coupled to any other reaction." [EC:3.6.1.3] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "adenylpyrophosphatase activity" RELATED [EC:3.6.1.3] xref: EC:3.6.1.3 xref: GO:0042624 xref: MetaCyc:ADENOSINETRIPHOSPHATASE-RXN is_a: CCO:F0003445 ! ATPase activity [Term] id: CCO:F0005698 name: ATPase activity, coupled to transmembrane movement of ions namespace: molecular_function def: "Catalysis of the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate." [EC:3.6.1.3, GOC:def, GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0042625 is_a: CCO:F0002557 ! ion transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0005699 name: ATPase activity, coupled to transmembrane movement of substances namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the active transport of a substance across a membrane." [EC:3.6.1.3, GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ABC transporter" NARROW [] synonym: "ABC-type efflux permease activity" NARROW [] synonym: "ABC-type efflux porter activity" NARROW [] synonym: "ABC-type uptake permease activity" NARROW [] synonym: "ATP binding cassette transporter" NARROW [] synonym: "ATP-binding cassette (ABC) transporter activity" NARROW [] synonym: "ATP-binding cassette transporter" NARROW [] synonym: "mating pheromone exporter" NARROW [] xref: GO:0042626 is_a: CCO:F0002826 ! P-P-bond-hydrolysis-driven transmembrane transporter activity is_a: CCO:F0003388 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances is_a: CCO:F0005860 ! ATPase activity, coupled to movement of substances [Term] id: CCO:F0005700 name: ecdysis-triggering hormone receptor activity namespace: molecular_function def: "Combining with ecdysis-triggering hormone to initiate a change in cell activity." [GOC:ma] synonym: "ecdysis-triggering hormone binding" NARROW [] synonym: "ETH receptor" EXACT [] xref: GO:0042654 is_a: CCO:F0001272 ! G-protein coupled receptor activity is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0005701 name: JUN kinase kinase kinase kinase activity namespace: molecular_function def: "Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs)." [GOC:bf] synonym: "JUNKKKK activity" EXACT [] xref: GO:0042656 is_a: CCO:F0001845 ! MAP kinase kinase kinase kinase activity [Term] id: CCO:F0005702 name: MHC class II protein binding, via lateral surface namespace: molecular_function def: "Interacting selectively with the lateral surface of major histocompatibility complex class II molecules." [GOC:jl] synonym: "major histocompatibility complex class II protein binding, via lateral surface" EXACT [] xref: GO:0042657 is_a: CCO:F0005649 ! MHC class II protein binding [Term] id: CCO:F0005703 name: MHC class II protein binding, via antigen binding groove namespace: molecular_function def: "Interacting selectively with the antigen binding groove of major histocompatibility complex class II molecules." [GOC:jl] synonym: "major histocompatibility complex class II protein binding, via antigen binding groove" EXACT [] xref: GO:0042658 is_a: CCO:F0005649 ! MHC class II protein binding [Term] id: CCO:F0005704 name: elastase activity namespace: molecular_function def: "Catalysis of the hydrolysis of elastin." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0042708 is_a: CCO:F0000644 ! endopeptidase activity [Term] id: CCO:F0005705 name: PH domain binding namespace: molecular_function def: "Interacting selectively with a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton." [GOC:jl, Pfam:PF00169] xref: GO:0042731 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0005706 name: NADH kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + NADH = ADP + NADPH." [PMID:12727869] synonym: "ATP:NADH 2'-phosphotransferase activity" EXACT [EC:2.7.1.86] synonym: "DPNH kinase activity" EXACT [EC:2.7.1.86] synonym: "reduced diphosphopyridine nucleotide kinase activity" EXACT [EC:2.7.1.86] synonym: "reduced nicotinamide adenine dinucleotide kinase (phosphorylating)" EXACT [EC:2.7.1.86] xref: EC:2.7.1.86 xref: GO:0042736 xref: MetaCyc:NADH-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0005707 name: ecdysteroid 22-hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 22." [PMID:12177427] comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22-dideoxyecdysone (ketotriol) to 2-deoxyecdysone. xref: GO:0042767 is_a: CCO:F0001866 ! steroid hydroxylase activity [Term] id: CCO:F0005708 name: ecdysteroid 2-hydroxylase activity namespace: molecular_function def: "Catalysis of the hydroxylation of an ecdysteroid at carbon position 2." [PMID:12177427] comment: Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2-deoxyecdysone to ecdysone. It can also catalyze the conversion of 2,22-dideoxyecdysone (ketotriol) to 22-deoxyecdysone. xref: GO:0042768 is_a: CCO:F0001866 ! steroid hydroxylase activity [Term] id: CCO:F0005709 name: 3'-tRNA processing endoribonuclease activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule." [EC:3.1.26.11] subset: gosubset_prok synonym: "3 tRNase activity" EXACT [EC:3.1.26.11] synonym: "3' tRNA processing endoribonuclease activity" EXACT [] synonym: "3' tRNase activity" BROAD [] synonym: "ribonuclease Z activity" BROAD [] synonym: "RNase Z activity" BROAD [] synonym: "tRNA 3 endonuclease activity" EXACT [EC:3.1.26.11] synonym: "tRNA 3' endonuclease activity" EXACT [] synonym: "tRNase Z" RELATED [EC:3.1.26.11] synonym: "tRNAse Z" RELATED [EC:3.1.26.11] xref: GO:0042781 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005710 name: histone lysine N-methyltransferase activity (H4-K20 specific) namespace: molecular_function def: "Catalysis of the addition of a methyl group onto lysine at position 20 of the histone H4 protein." [PMID:12086618] comment: Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H4 protein, but that this term still applies. synonym: "histone H4 lysine 20-specific methyltransferase activity" EXACT [] xref: GO:0042799 is_a: CCO:F0003617 ! histone-lysine N-methyltransferase activity [Term] id: CCO:F0005711 name: histone lysine N-methyltransferase activity (H3-K4 specific) namespace: molecular_function def: "Catalysis of the addition of a methyl group onto lysine at position 4 of the histone H3 protein." [PMID:12589755] comment: Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H3 protein, but that this term still applies. synonym: "histone H3 lysine 4-specific methyltransferase activity" EXACT [] xref: GO:0042800 is_a: CCO:F0003617 ! histone-lysine N-methyltransferase activity [Term] id: CCO:F0005712 name: polo kinase kinase activity namespace: molecular_function def: "Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins." [GOC:ma] xref: GO:0042801 is_a: CCO:F0001068 ! receptor signaling protein serine/threonine kinase activity [Term] id: CCO:F0005713 name: identical protein binding namespace: molecular_function def: "Interacting selectively with an identical protein or proteins." [GOC:jl] subset: gosubset_prok synonym: "protein homopolymerization" RELATED [] xref: GO:0042802 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005714 name: protein homodimerization activity namespace: molecular_function def: "Interacting selectively with an identical protein to form a homodimer." [GOC:jl] subset: gosubset_prok synonym: "dimerization activity" BROAD [] xref: GO:0042803 is_a: CCO:F0005713 ! identical protein binding is_a: CCO:F0006300 ! protein dimerization activity [Term] id: CCO:F0005715 name: actinin binding namespace: molecular_function def: "Interacting selectively with actinin, any member of a family of proteins that crosslink F-actin." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0042805 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0005716 name: fucose binding namespace: molecular_function def: "Interacting selectively with fucose, a 5-carbon (pentose) sugar." [ISBN:0582227089] xref: GO:0042806 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0005717 name: neuronal Cdc2-like kinase binding namespace: molecular_function def: "Interacting selectively with neuronal Cdc2-like kinase, an enzyme involved in the regulation of neuronal differentiation and neuro-cytoskeleton dynamics." [GOC:jl, PMID:10721722] xref: GO:0042808 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0005718 name: vitamin D receptor binding namespace: molecular_function def: "Interacting selectively with the vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes." [GOC:jl, UniProtKB:P11473] synonym: "calciferol receptor binding" EXACT [] synonym: "VDR binding" EXACT [] xref: GO:0042809 is_a: CCO:F0001738 ! transcription factor binding is_a: CCO:F0005585 ! nuclear hormone receptor binding [Term] id: CCO:F0005719 name: Wnt receptor activity namespace: molecular_function def: "Combining with a member of the Wnt family of signaling molecules to initiate a change in cell activity." [GOC:go_curators] synonym: "frizzled receptor activity" RELATED [] synonym: "frizzled-2 receptor activity" RELATED [] xref: GO:0042813 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0005720 name: histone deacetylase binding namespace: molecular_function def: "Interacting selectively with the enzyme histone deacetylase." [GOC:jl] xref: GO:0042826 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0005721 name: peptidoglycan binding namespace: molecular_function def: "Interacting selectively, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls." [GOC:go_curators, PMID:14698226] subset: gosubset_prok xref: GO:0042834 is_a: CCO:F0000239 ! pattern binding [Term] id: CCO:F0005722 name: BRE binding namespace: molecular_function def: "Interacting selectively with the RNA element BRE (Bruno response element)." [PMID:10893231] xref: GO:0042835 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0005723 name: aldarate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of aldarate from one side of the membrane to the other." [GOC:go_curators, PMID:15034926] subset: gosubset_prok xref: GO:0042876 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0005724 name: D-galactarate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-galactarate, the dextrorotatory isomer of the anion of galactaric acid, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok xref: GO:0042877 is_a: CCO:F0005723 ! aldarate transmembrane transporter activity [Term] id: CCO:F0005725 name: D-glucarate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-glucarate, the dextrorotatory isomer of glucarate, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok xref: GO:0042878 is_a: CCO:F0005723 ! aldarate transmembrane transporter activity [Term] id: CCO:F0005726 name: aldonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of aldonate from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0042879 is_a: CCO:F0002626 ! hexose transmembrane transporter activity [Term] id: CCO:F0005727 name: D-glucuronate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-glucuronate, the dextrorotatory isomer of glucuronate, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] subset: gosubset_prok xref: GO:0042880 is_a: CCO:F0005726 ! aldonate transmembrane transporter activity [Term] id: CCO:F0005728 name: D-galactonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-galactonate, the dextrorotatory isomer of galactonate, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729] xref: GO:0042881 is_a: CCO:F0005726 ! aldonate transmembrane transporter activity [Term] id: CCO:F0005729 name: amide transporter activity namespace: molecular_function def: "Enables the directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of, within or between cells." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "amine/amide/polyamine channel activity" NARROW [] xref: GO:0042887 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0005730 name: molybdenum ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of molybdenum (Mo) ions from one side of a membrane to the other." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0042888 is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0005731 name: 3-phenylpropionic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of 3-phenylpropionic acid from one side of the membrane to the other." [GOC:jl] synonym: "3-phenylpropionate acid transporter activity" EXACT [] synonym: "HCA transporter activity" EXACT [] synonym: "hydrocinnamic acid transporter activity" EXACT [] xref: GO:0042890 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0005732 name: antibiotic transporter activity namespace: molecular_function def: "Enables the directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of, within or between cells." [GOC:jl] subset: gosubset_prok xref: GO:0042895 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0005733 name: chloramphenicol transporter activity namespace: molecular_function def: "Enables the directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, into, out of, within or between cells." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok xref: GO:0042896 is_a: CCO:F0005732 ! antibiotic transporter activity [Term] id: CCO:F0005734 name: polymyxin transporter activity namespace: molecular_function def: "Enables the directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of, within or between cells." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0042897 is_a: CCO:F0005732 ! antibiotic transporter activity [Term] id: CCO:F0005735 name: fosmidomycin transporter activity namespace: molecular_function def: "Enables the directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of, within or between cells." [GOC:jl, PMID:12543685] subset: gosubset_prok xref: GO:0042898 is_a: CCO:F0005732 ! antibiotic transporter activity [Term] id: CCO:F0005736 name: arabinose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, http://cancerweb.ncl.ac.uk/, ISBN:0815340729] subset: gosubset_prok xref: GO:0042900 is_a: CCO:F0002623 ! pentose transmembrane transporter activity [Term] id: CCO:F0005737 name: arabinose polymer transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an arabinose polymer, a repeating chain of arabinose monomers, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] xref: GO:0042901 is_a: CCO:F0005736 ! arabinose transmembrane transporter activity [Term] id: CCO:F0005738 name: tubulin deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate." [PMID:12024216, PMID:12486003] xref: GO:0042903 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0005179 ! protein deacetylase activity [Term] id: CCO:F0005739 name: xanthine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids." [GOC:jl] xref: GO:0042907 is_a: CCO:F0001573 ! purine transmembrane transporter activity [Term] id: CCO:F0005740 name: xenobiotic transporter activity namespace: molecular_function def: "Enables the directed movement of a xenobiotic, a compound foreign to living organisms, into, out of, within or between cells." [GOC:go_curators] subset: gosubset_prok xref: GO:0042910 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0005741 name: acridine transporter activity namespace: molecular_function def: "Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of, within or between cells." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok xref: GO:0042911 is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0005742 name: colicin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1." [GOC:jl, GOC:mtg_transport, http://cancerweb.ncl.ac.uk/, ISBN:0815340729] subset: gosubset_prok xref: GO:0042912 is_a: CCO:F0004306 ! bacteriocin transmembrane transporter activity [Term] id: CCO:F0005743 name: group A colicin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729, PMID:9171417] subset: gosubset_prok xref: GO:0042913 is_a: CCO:F0005742 ! colicin transmembrane transporter activity [Term] id: CCO:F0005744 name: alkylphosphonate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an alkylphosphonate from one side of a membrane to the other." [GOC:go_curators] subset: gosubset_prok xref: GO:0042917 is_a: CCO:F0002967 ! phosphonate transmembrane transporter activity [Term] id: CCO:F0005745 name: neuromedin U receptor binding namespace: molecular_function def: "Interacting selectively with one or more specific sites on a neuromedin U receptor." [GOC:jl, PMID:10899166] xref: GO:0042922 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0005746 name: neuropeptide binding namespace: molecular_function def: "Interacting selectively and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators)." [http://cancerweb.ncl.ac.uk/] xref: GO:0042923 is_a: CCO:F0005633 ! neurotransmitter binding is_a: CCO:F0005639 ! peptide binding [Term] id: CCO:F0005747 name: neuromedin U binding namespace: molecular_function def: "Interacting selectively and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses." [GOC:jl, PMID:12584108] synonym: "NMU binding" EXACT [] xref: GO:0042924 is_a: CCO:F0005746 ! neuropeptide binding [Term] id: CCO:F0005748 name: benzoate transporter activity namespace: molecular_function def: "Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of, within or between cells." [GOC:jl, ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok xref: GO:0042925 is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0005749 name: 3-hydroxyphenylpropionic acid transporter activity namespace: molecular_function def: "Enables the directed movement of 3-hydroxyphenylpropionic acid into, out of, within or between cells." [GOC:jl] subset: gosubset_prok synonym: "3-(3-hydroxyphenyl)propionic acid transporter activity" EXACT [] synonym: "m-hydroxyphenylpropionic acid transporter activity" EXACT [] xref: GO:0042926 is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0005750 name: siderophore transporter activity namespace: molecular_function def: "Enables the directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of, within or between cells." [GOC:go_curators] subset: gosubset_prok synonym: "siderochrome transporter activity" NARROW [] xref: GO:0042927 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0005751 name: ferrichrome transporter activity namespace: molecular_function def: "Enables the directed movement of a ferrichrome into, out of, within or between cells. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0042929 is_a: CCO:F0005750 ! siderophore transporter activity [Term] id: CCO:F0005752 name: enterobactin transporter activity namespace: molecular_function def: "Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of, within or between cells." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "enterochelin transporter activity" EXACT [] xref: GO:0042931 is_a: CCO:F0005750 ! siderophore transporter activity [Term] id: CCO:F0005753 name: chrysobactin transporter activity namespace: molecular_function def: "Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of, within or between cells." [GOC:jl, PMID:8837459] subset: gosubset_prok xref: GO:0042933 is_a: CCO:F0005750 ! siderophore transporter activity [Term] id: CCO:F0005754 name: achromobactin transporter activity namespace: molecular_function def: "Enables the directed movement of achromobactin, a citrate siderophore, into, out of, within or between cells." [GOC:jl] subset: gosubset_prok xref: GO:0042934 is_a: CCO:F0005750 ! siderophore transporter activity is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0005755 name: dipeptide transporter activity namespace: molecular_function def: "Enables the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of, within or between cells." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok xref: GO:0042936 is_a: CCO:F0002672 ! oligopeptide transporter activity [Term] id: CCO:F0005756 name: tripeptide transporter activity namespace: molecular_function def: "Enables the directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of, within or between cells." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok xref: GO:0042937 is_a: CCO:F0002672 ! oligopeptide transporter activity [Term] id: CCO:F0005757 name: D-amino acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the dextrorotatory isomer of amino acids." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "D-amino acid transporter activity" BROAD [] xref: GO:0042943 is_a: CCO:F0002648 ! amino acid transmembrane transporter activity [Term] id: CCO:F0005758 name: D-alanine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-alanine from one side of a membrane to the other. D-alanine is the dextrorotatory isomer of 2-aminopropanoic acid." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "D-alanine transporter activity" BROAD [] xref: GO:0042944 is_a: CCO:F0004285 ! alanine transmembrane transporter activity is_a: CCO:F0005757 ! D-amino acid transmembrane transporter activity [Term] id: CCO:F0005759 name: D-serine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-serine from one side of a membrane to the other. D-serine is the dextrorotatory isomer of 2-amino-3-hydroxypropanoic acid." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "D-serine permease activity" EXACT [] synonym: "D-serine transporter activity" BROAD [] xref: GO:0042945 is_a: CCO:F0004308 ! serine transmembrane transporter activity is_a: CCO:F0005757 ! D-amino acid transmembrane transporter activity [Term] id: CCO:F0005760 name: glucoside transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glucosides from one side of the membrane to the other. Glucosides are glycosides in which the sugar moiety is a glucose residue." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok xref: GO:0042947 is_a: CCO:F0008062 ! sugar transmembrane transporter activity [Term] id: CCO:F0005761 name: salicin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, http://cancerweb.ncl.ac.uk/, ISBN:0815340729] subset: gosubset_prok xref: GO:0042950 is_a: CCO:F0002953 ! beta-glucoside transmembrane transporter activity [Term] id: CCO:F0005762 name: arbutin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of the membrane to the other." [GOC:jl, GOC:mtg_transport, http://biotech.icmb.utexas.edu/, ISBN:0815340729] xref: GO:0042951 is_a: CCO:F0002953 ! beta-glucoside transmembrane transporter activity [Term] id: CCO:F0005763 name: lipoprotein transporter activity namespace: molecular_function def: "Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids, into, out of, within or between cells." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0042954 is_a: CCO:F0001997 ! protein transporter activity [Term] id: CCO:F0005764 name: dextrin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of the membrane to the other." [GOC:jl, GOC:vk, http://www.mercksource.com/] subset: gosubset_prok xref: GO:0042957 is_a: CCO:F0002636 ! polysaccharide transmembrane transporter activity [Term] id: CCO:F0005765 name: maltodextrin transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of the membrane to the other." [GOC:jl, http://www.mercksource.com/, PMID:15034926] subset: gosubset_prok xref: GO:0042958 is_a: CCO:F0005764 ! dextrin transmembrane transporter activity [Term] id: CCO:F0005766 name: alkanesulfonate transporter activity namespace: molecular_function def: "Enables the directed movement of alkanesulfonate into, out of, within or between cells." [GOC:jl] subset: gosubset_prok synonym: "alkanesulphonate transporter activity" EXACT [] xref: GO:0042959 is_a: CCO:F0005740 ! xenobiotic transporter activity [Term] id: CCO:F0005767 name: antimonite secondary active transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport." [GOC:jl] subset: gosubset_prok synonym: "antimonite porter activity" RELATED [] xref: GO:0042960 is_a: CCO:F0002582 ! antimonite transmembrane transporter activity is_a: CCO:F0002740 ! secondary active transmembrane transporter activity [Term] id: CCO:F0005768 name: antimonite-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out)." [EC:3.6.3.16] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "antimonite ABC transporter" NARROW [] xref: GO:0042961 is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances is_a: CCO:F0005767 ! antimonite secondary active transmembrane transporter activity [Term] id: CCO:F0005769 name: acridine:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out)." [PMID:10735876] subset: gosubset_prok synonym: "acridine efflux pump activity" RELATED [] synonym: "acridine:proton antiporter activity" EXACT [] xref: GO:0042962 is_a: CCO:F0002748 ! solute:hydrogen antiporter activity is_a: CCO:F0005741 ! acridine transporter activity [Term] id: CCO:F0005770 name: homoserine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "homoserine transporter activity" BROAD [] xref: GO:0042970 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity [Term] id: CCO:F0005771 name: lactone transporter activity namespace: molecular_function def: "Enables the directed movement of lactone, any of a series of organic compounds, regarded as anhydrides of certain hydroxy acids, into, out of, within or between cells." [GOC:go_curators, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok xref: GO:0042971 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0005772 name: licheninase activity namespace: molecular_function def: "Catalysis of the hydrolysis of 1,4-beta-D-glucosidic linkages in beta-D-glucans containing 1,3- and 1,4-bonds." [EC:3.2.1.73] subset: gosubset_prok synonym: "1,3-1,4-beta-D-glucan 4-glucanohydrolase activity" EXACT [] synonym: "1,3-1,4-beta-glucan 4-glucanohydrolase activity" EXACT [] synonym: "1,3;1,4-beta-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.73] synonym: "1,3;1,4-beta-glucan endohydrolase activity" EXACT [EC:3.2.1.73] synonym: "beta-(1->3), (1->4)-D-glucan 4-glucanohydrolase activity" EXACT [EC:3.2.1.73] synonym: "beta-glucanase activity" BROAD [EC:3.2.1.73] synonym: "endo-beta-1,3-1,4 glucanase activity" EXACT [EC:3.2.1.73] synonym: "lichenase activity" EXACT [] synonym: "mixed linkage beta-glucanase activity" RELATED [EC:3.2.1.73] xref: EC:3.2.1.73 xref: GO:0042972 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005773 name: glucan endo-1,3-beta-D-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans." [EC:3.2.1.39] subset: gosubset_prok synonym: "(1->3)-beta-glucan 3-glucanohydrolase activity" EXACT [EC:3.2.1.39] synonym: "(1->3)-beta-glucan endohydrolase activity" EXACT [EC:3.2.1.39] synonym: "1,3-beta-D-glucan 3-glucanohydrolase activity" EXACT [EC:3.2.1.39] synonym: "1,3-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.39] synonym: "beta-1,3-glucanase" BROAD [EC:3.2.1.39] synonym: "callase activity" EXACT [EC:3.2.1.39] synonym: "endo-(1,3)-beta-D-glucanase activity" BROAD [EC:3.2.1.39] synonym: "endo-(1->3)-beta-D-glucanase activity" BROAD [EC:3.2.1.39] synonym: "endo-1,3-beta-D-glucanase" BROAD [EC:3.2.1.39] synonym: "endo-1,3-beta-glucanase activity" BROAD [] synonym: "endo-1,3-beta-glucosidase activity" BROAD [EC:3.2.1.39] synonym: "kitalase activity" EXACT [EC:3.2.1.39] synonym: "laminaranase activity" BROAD [] synonym: "laminarinase activity" BROAD [] synonym: "oligo-1,3-glucosidase activity" RELATED [EC:3.2.1.39] xref: EC:3.2.1.39 xref: GO:0042973 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0005774 name: retinoic acid receptor binding namespace: molecular_function def: "Interacting selectively with the retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily." [GOC:jl, PMID:12476796] synonym: "RAR binding" EXACT [] xref: GO:0042974 is_a: CCO:F0001738 ! transcription factor binding is_a: CCO:F0005585 ! nuclear hormone receptor binding [Term] id: CCO:F0005775 name: peroxisome proliferator activated receptor binding namespace: molecular_function def: "Interacting selectively with any of the peroxisome proliferator activated receptors, alpha, beta or gamma." [GOC:jl, PMID:12769781] synonym: "PPAR binding" EXACT [] xref: GO:0042975 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005776 name: ornithine decarboxylase activator activity namespace: molecular_function def: "Upregulation of the activity of the enzyme ornithine decarboxylase." [GOC:jl] synonym: "L-ornithine carboxy-lyase activator activity" NARROW [] xref: GO:0042978 is_a: CCO:F0001691 ! enzyme activator activity is_a: CCO:F0005777 ! ornithine decarboxylase regulator activity [Term] id: CCO:F0005777 name: ornithine decarboxylase regulator activity namespace: molecular_function def: "Modulation of the activity of the enzyme ornithine decarboxylase." [GOC:jl] xref: GO:0042979 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0005778 name: cystic fibrosis transmembrane conductance regulator binding namespace: molecular_function def: "Interacting selectively with the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein." [GOC:jl] synonym: "CFTR binding" EXACT [] xref: GO:0042980 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005779 name: X11-like protein binding namespace: molecular_function def: "Interacting selectively with X11-like protein, a neuron-specific adaptor protein." [GOC:jl, PMID:12780348] synonym: "X11L binding" EXACT [] xref: GO:0042988 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005780 name: ATP-dependent protein binding namespace: molecular_function def: "Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP." [GOC:jl] xref: GO:0043008 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005781 name: alpha-tubulin binding namespace: molecular_function def: "Interacting selectively with the microtubule constituent protein alpha-tubulin." [GOC:jl] synonym: "alpha tubulin binding" EXACT [] xref: GO:0043014 is_a: CCO:F0002987 ! tubulin binding [Term] id: CCO:F0005782 name: gamma-tubulin binding namespace: molecular_function def: "Interacting selectively with the microtubule constituent protein gamma-tubulin." [GOC:jl] synonym: "gamma tubulin binding" EXACT [] xref: GO:0043015 is_a: CCO:F0002987 ! tubulin binding [Term] id: CCO:F0005783 name: ribonucleoprotein binding namespace: molecular_function def: "Interacting selectively with any complex of RNA and protein." [GOC:go_curators] subset: goslim_pir subset: gosubset_prok synonym: "RNP binding" EXACT [] xref: GO:0043021 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005784 name: ribosome binding namespace: molecular_function def: "Interacting selectively with any part of a ribosome." [GOC:go_curators] subset: gosubset_prok synonym: "ribosome receptor activity" NARROW [] xref: GO:0030376 xref: GO:0043022 is_a: CCO:F0005783 ! ribonucleoprotein binding [Term] id: CCO:F0005785 name: ribosomal large subunit binding namespace: molecular_function def: "Interacting selectively with any part of the larger ribosomal subunit." [GOC:go_curators] subset: gosubset_prok xref: GO:0043023 is_a: CCO:F0005783 ! ribonucleoprotein binding [Term] id: CCO:F0005786 name: ribosomal small subunit binding namespace: molecular_function def: "Interacting selectively with any part of the small ribosomal subunit." [GOC:go_curators] subset: gosubset_prok xref: GO:0043024 is_a: CCO:F0005783 ! ribonucleoprotein binding [Term] id: CCO:F0005787 name: caspase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a caspase, any of a group of cysteine proteases involved in apoptosis." [GOC:jl, http://en.wikipedia.org/wiki/ "Wikipedia"] xref: GO:0043027 is_a: CCO:F0001222 ! endopeptidase inhibitor activity is_a: CCO:F0005788 ! caspase regulator activity [Term] id: CCO:F0005788 name: caspase regulator activity namespace: molecular_function def: "Modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis." [GOC:jl, http://en.wikipedia.org/wiki/ "Wikipedia"] xref: GO:0043028 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0005789 name: chromatin insulator sequence binding namespace: molecular_function def: "Interacting selectively and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription." [GOC:jl, PMID:12783795] xref: GO:0043035 is_a: CCO:F0004674 ! chromatin DNA binding [Term] id: CCO:F0005790 name: single-stranded telomeric DNA binding namespace: molecular_function def: "Interacting selectively with single-stranded telomere-associated DNA." [GOC:jl, ISBN:0321000382] xref: GO:0043047 is_a: CCO:F0000288 ! single-stranded DNA binding is_a: CCO:F0005630 ! telomeric DNA binding [Term] id: CCO:F0005791 name: GTP cyclohydrolase I binding namespace: molecular_function def: "Interacting selectively with the enzyme GTP cyclohydrolase I." [GOC:jl] xref: GO:0043106 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0005792 name: rDNA spacer replication fork barrier binding namespace: molecular_function def: "Interacting selectively with replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription." [GOC:jl, GOC:mah, PMID:14645529] synonym: "RFB binding" EXACT [] xref: GO:0043110 is_a: CCO:F0000036 ! rDNA binding is_a: CCO:F0004692 ! replication fork barrier binding [Term] id: CCO:F0005793 name: precorrin-2 dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: precorrin-2 (dihydrosirohydrochlorin) + NAD+ = sirohydrochlorin + NADH + H+." [EC:1.3.1.76] subset: gosubset_prok synonym: "1,3-dimethyluroporphyrinogen III dehydrogenase activity" EXACT [] synonym: "CysG" RELATED [EC:1.3.1.76] synonym: "dihydrosirohydrochlorin dehydrogenase activity" EXACT [] synonym: "Met8p" RELATED [EC:1.3.1.76] synonym: "precorrin-2 oxidase activity" EXACT [EC:1.3.1.76] synonym: "precorrin-2:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.76] synonym: "SirC" RELATED [EC:1.3.1.76] synonym: "siroheme synthase activity" BROAD [] xref: EC:1.3.1.76 xref: GO:0043115 xref: MetaCyc:DIMETHUROPORDEHYDROG-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005794 name: tumor necrosis factor binding namespace: molecular_function def: "Interacting selectively with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages." [GOC:jl, http://lookwayup.com/] xref: GO:0043120 is_a: CCO:F0004221 ! cytokine binding [Term] id: CCO:F0005795 name: neurotrophin binding namespace: molecular_function def: "Interacting selectively with neurotrophin, any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth." [GOC:jl, http://www.mercksource.com/] synonym: "neurotrophin TRK receptor activity" RELATED [] xref: GO:0043121 is_a: CCO:F0004188 ! growth factor binding [Term] id: CCO:F0005796 name: ErbB-3 class receptor binding namespace: molecular_function def: "Interacting selectively with the protein-tyrosine kinase receptor ErbB-3/HER3." [GOC:jl] synonym: "HER3 receptor binding" EXACT [] synonym: "Neu/ErbB-2 receptor activity" RELATED [] xref: GO:0043125 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0005797 name: ubiquitin binding namespace: molecular_function def: "Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation." [GOC:ecd] xref: GO:0043130 is_a: CCO:F0004963 ! small conjugating protein binding [Term] id: CCO:F0005798 name: 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of the diphosphate bond in 5-phosphoribosyl 1-pyrophosphate." [GOC:jl, http://cancerweb.ncl.ac.uk, PMID:12370170] synonym: "PRPP pyrophosphatase activity" EXACT [] xref: GO:0043135 is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0005799 name: glycerol-3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate." [GOC:jl] xref: GO:0043136 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005800 name: 3'-5' DNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of the DNA helix in the direction 3' to 5'." [GOC:jl] synonym: "3' to 5' DNA helicase activity" EXACT [] xref: GO:0043138 is_a: CCO:F0000275 ! DNA helicase activity [Term] id: CCO:F0005801 name: 5'-3' DNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of the DNA helix in the direction 5' to 3'." [GOC:jl] synonym: "5' to 3' DNA helicase activity" EXACT [] xref: GO:0043139 is_a: CCO:F0000275 ! DNA helicase activity [Term] id: CCO:F0005802 name: ATP-dependent 3'-5' DNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'." [GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP-dependent 3' to 5' DNA helicase activity" EXACT [] xref: GO:0043140 is_a: CCO:F0000487 ! ATP-dependent DNA helicase activity is_a: CCO:F0005800 ! 3'-5' DNA helicase activity [Term] id: CCO:F0005803 name: ATP-dependent 5'-3' DNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'." [GOC:jl] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP-dependent 5' to 3' DNA helicase activity" EXACT [] synonym: "DNA helicase IV activity" NARROW [] xref: EC:3.6.1.- xref: GO:0008722 xref: GO:0043141 is_a: CCO:F0000487 ! ATP-dependent DNA helicase activity is_a: CCO:F0005801 ! 5'-3' DNA helicase activity [Term] id: CCO:F0005804 name: single-stranded DNA-dependent ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate in the presence of single-stranded DNA; drives another reaction." [GOC:go_curators] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ssDNA-dependent ATPase activity" EXACT [] xref: GO:0043142 is_a: CCO:F0001707 ! DNA-dependent ATPase activity [Term] id: CCO:F0005805 name: H4/H2A histone acetyltransferase activity namespace: molecular_function def: "Catalysis of the addition of an acetyl group to a histone, specific for histones H4 and (to a lesser extent) H2A." [GOC:jl, PMID:10911987, PMID:9241414] synonym: "H4/H2A acetyltransferase activity" EXACT [] xref: GO:0043166 is_a: CCO:F0000813 ! histone acetyltransferase activity [Term] id: CCO:F0005806 name: ion binding namespace: molecular_function def: "Interacting selectively with ions, charged atoms or groups of atoms." [GOC:jl] subset: goslim_pir subset: gosubset_prok synonym: "atom binding" RELATED [] xref: GO:0043167 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005807 name: anion binding namespace: molecular_function def: "Interacting selectively with anions, charged atoms or groups of atoms with a net negative charge." [GOC:jl] subset: gosubset_prok xref: GO:0043168 is_a: CCO:F0005806 ! ion binding [Term] id: CCO:F0005808 name: cation binding namespace: molecular_function def: "Interacting selectively with cations, charged atoms or groups of atoms with a net positive charge." [GOC:jl] subset: gosubset_prok xref: GO:0043169 is_a: CCO:F0005806 ! ion binding [Term] id: CCO:F0005809 name: RNA polymerase core enzyme binding namespace: molecular_function def: "Interacting selectively with the prokaryotic RNA polymerase core enzyme, the part of the RNA polymerase consisting of two alpha, one beta and one beta prime subunits." [GOC:jl, ISBN:0321000382] subset: gosubset_prok xref: GO:0043175 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0005810 name: amine binding namespace: molecular_function def: "Interacting selectively with any organic compound that is weakly basic in character and contains an amino or a substituted amino group." [GOC:jl] subset: goslim_pir subset: gosubset_prok xref: GO:0043176 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005811 name: organic acid binding namespace: molecular_function def: "Interacting selectively with an organic acid, any acidic compound containing carbon in covalent linkage." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0043177 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005812 name: alcohol binding namespace: molecular_function def: "Interacting selectively with an alcohol, any of a class of alkyl compounds containing a hydroxyl group." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0043178 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005813 name: vascular endothelial growth factor receptor 1 binding namespace: molecular_function def: "Interacting selectively with vascular endothelial growth factor receptor 1." [GOC:st] synonym: "Flt-1 binding" EXACT [] synonym: "VEGF receptor 1 binding" EXACT [] synonym: "VEGFR 1 binding" EXACT [] xref: GO:0043183 is_a: CCO:F0001473 ! vascular endothelial growth factor receptor binding [Term] id: CCO:F0005814 name: vascular endothelial growth factor receptor 2 binding namespace: molecular_function def: "Interacting selectively with vascular endothelial growth factor receptor 2." [GOC:st] synonym: "Flk-1 binding" EXACT [] synonym: "KDR binding" BROAD [] synonym: "kinase domain region binding" EXACT [] synonym: "VEGF receptor 2 binding" EXACT [] synonym: "VEGFR 2 binding" EXACT [] xref: GO:0043184 is_a: CCO:F0001473 ! vascular endothelial growth factor receptor binding [Term] id: CCO:F0005815 name: vascular endothelial growth factor receptor 3 binding namespace: molecular_function def: "Interacting selectively with vascular endothelial growth factor receptor 3." [GOC:st] synonym: "fms-like-tyrosine kinase (Flt)-4 binding" EXACT [] synonym: "VEGF receptor 3 binding" EXACT [] synonym: "VEGFR 3 binding" EXACT [] xref: GO:0043185 is_a: CCO:F0001473 ! vascular endothelial growth factor receptor binding [Term] id: CCO:F0005816 name: sulfate binding namespace: molecular_function def: "Interacting selectively with sulfate (SO42-), a negatively charged small molecule." [GOC:mlg] subset: gosubset_prok xref: GO:0043199 is_a: CCO:F0005807 ! anion binding [Term] id: CCO:F0005817 name: glycosphingolipid binding namespace: molecular_function def: "Interacting selectively with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide." [GOC:jl] xref: GO:0043208 is_a: CCO:F0006239 ! sphingolipid binding is_a: CCO:F0008198 ! glycolipid binding [Term] id: CCO:F0005818 name: alkanesulfonate binding namespace: molecular_function def: "Interacting selectively with alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon moiety." [GOC:mlg] subset: gosubset_prok xref: GO:0043210 is_a: CCO:F0005807 ! anion binding [Term] id: CCO:F0005819 name: carbohydrate-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of carbohydrates across a membrane." [GOC:mlg] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "carbohydrate ABC transporter" NARROW [] xref: GO:0043211 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0005820 name: carbohydrate-exporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) = ADP + phosphate + carbohydrate(out)." [GOC:mlg] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok xref: GO:0043212 is_a: CCO:F0005819 ! carbohydrate-transporting ATPase activity [Term] id: CCO:F0005821 name: bacteriocin-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of bacteriocins across a membrane." [GOC:mlg] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "bacteriocin ABC transporter" NARROW [] xref: GO:0043214 is_a: CCO:F0002869 ! protein-transmembrane transporting ATPase activity [Term] id: CCO:F0005822 name: daunorubicin-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out)." [GOC:mlg] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "daunorubicin ABC transporter" NARROW [] xref: GO:0043216 is_a: CCO:F0002706 ! drug transporter activity is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0005823 name: SMC protein binding namespace: molecular_function def: "Interacting selectively with any protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization." [GOC:jl, PMID:9640531] xref: GO:0043221 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005824 name: anion transmembrane-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + anion(out) = ADP + phosphate + anion(in)." [GOC:mlg] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "anion ABC transporter" NARROW [] synonym: "anion-transporting ATPase activity" EXACT [] xref: GO:0043225 is_a: CCO:F0001962 ! anion transmembrane transporter activity is_a: CCO:F0005698 ! ATPase activity, coupled to transmembrane movement of ions [Term] id: CCO:F0005825 name: laminin binding namespace: molecular_function def: "Interacting selectively with laminins, glycoproteins that are major constituents of the basement membrane of cells." [GOC:ecd] xref: GO:0043236 is_a: CCO:F0001646 ! protein binding is_a: CCO:F0008024 ! extracellular matrix binding [Term] id: CCO:F0005826 name: laminin-1 binding namespace: molecular_function def: "Interacting selectively with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1." [GOC:go_curators] xref: GO:0043237 is_a: CCO:F0005825 ! laminin binding [Term] id: CCO:F0005827 name: laminin-2 binding namespace: molecular_function def: "Interacting selectively with laminin-2, a glycoprotein trimer with the subunit composition alpha2, beta1, gamma 1." [GOC:go_curators] xref: GO:0043238 is_a: CCO:F0005825 ! laminin binding [Term] id: CCO:F0005828 name: laminin-4 binding namespace: molecular_function def: "Interacting selectively with laminin-4, a glycoprotein trimer with the subunit composition alpha2, beta2, gamma 1." [GOC:go_curators] xref: GO:0043239 is_a: CCO:F0005825 ! laminin binding [Term] id: CCO:F0005829 name: sodium-dependent organic anion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner." [GOC:go_curators] xref: GO:0043250 is_a: CCO:F0001967 ! organic anion transmembrane transporter activity [Term] id: CCO:F0005830 name: adenosine-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: ADP + H2O = AMP + phosphate." [EC:3.6.1.5, PMID:1470606] synonym: "adenosine diphosphatase activity" EXACT [] synonym: "adenosinepyrophosphatase activity" EXACT [EC:3.6.1.6] synonym: "ADPase" BROAD [EC:3.6.1.3] synonym: "ADPase activity" EXACT [EC:3.6.1.6] synonym: "ATP diphosphohydrolase" BROAD [EC:3.6.1.3] synonym: "ATP diphosphohydrolase (phosphate-forming) activity" EXACT [EC:3.6.1.3] synonym: "ATP-diphosphatase activity" EXACT [EC:3.6.1.3] synonym: "ATP-diphosphohydrolase activity" EXACT [EC:3.6.1.3] xref: GO:0043262 is_a: CCO:F0003573 ! nucleoside-diphosphatase activity [Term] id: CCO:F0005831 name: CTPase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction." [GOC:go_curators] synonym: "cytidine triphosphatase activity" EXACT [] xref: GO:0043273 is_a: CCO:F0003574 ! nucleoside-triphosphatase activity [Term] id: CCO:F0005832 name: phospholipase binding namespace: molecular_function def: "Interacting selectively with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid." [GOC:jl] xref: GO:0043274 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0005833 name: glutamate carboxypeptidase II activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu." [BRENDA:3.4.17.21, GOC:jl] comment: Note that this function was formerly EC:3.4.19.8. synonym: "acetylaspartylglutamate dipeptidase activity" EXACT [] synonym: "folate hydrolase activity" RELATED [EC:3.4.17.21] synonym: "folylpolyglutamate hydrolase activity" EXACT [EC:3.4.17.21] synonym: "membrane glutamate carboxypeptidase" NARROW [EC:3.4.17.21] synonym: "mGCP" RELATED [EC:3.4.17.21] synonym: "microsomal gamma-glutamyl carboxypeptidase" NARROW [EC:3.4.17.21] synonym: "N-acetylated alpha-linked acidic dipeptidase activity" EXACT [EC:3.4.17.21] synonym: "N-acetylated-alpha-linked-amino dipeptidase activity" EXACT [EC:3.4.17.21] synonym: "N-acetylated-gamma-linked-acidic dipeptidase (NAALADase)" EXACT [EC:3.4.17.21] synonym: "N-acetylated-gamma-linked-acidic dipeptidase activity" EXACT [EC:3.4.17.21] synonym: "NAALA dipeptidase activity" EXACT [EC:3.4.17.21] synonym: "NAALADase activity" EXACT [EC:3.4.17.21] synonym: "prostate-specific membrane antigen" RELATED [EC:3.4.17.21] synonym: "prostrate-specific membrane antigen" RELATED [EC:3.4.17.21] synonym: "PSM antigen" RELATED [EC:3.4.17.21] synonym: "PSMA" RELATED [EC:3.4.17.21] synonym: "pteroylpoly-gamma-glutamate carboxypeptidase activity" EXACT [EC:3.4.17.21] synonym: "pteroylpoly-gamma-glutamate hydrolase activity" EXACT [EC:3.4.17.21] synonym: "pteroylpolygammaglutamyl hydrolase activity" EXACT [EC:3.4.17.21] synonym: "pteroylpolyglutamate hydrolase activity" EXACT [EC:3.4.17.21] synonym: "pteroylpolyglutamic acid hydrolase activity" EXACT [EC:3.4.17.21] synonym: "rat NAAG peptidase" NARROW [EC:3.4.17.21] xref: EC:3.4.17.21 xref: GO:0043275 is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0005834 name: poly(3-hydroxyalkanoate) binding namespace: molecular_function def: "Interacting selectively with poly(3-hydroxyalkanoate)s, polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria." [GOC:jl] subset: gosubset_prok synonym: "PHA binding" EXACT [] xref: GO:0043287 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005835 name: glutathione binding namespace: molecular_function def: "Interacting selectively with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine." [GOC:bf, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0043295 is_a: CCO:F0005639 ! peptide binding [Term] id: CCO:F0005836 name: phosphatidylinositol-3,4-bisphosphate binding namespace: molecular_function def: "Interacting selectively with phosphatidylinositol-3,4-bisphosphate, a diphosphorylated derivative of phosphatidylinositol." [GOC:go_curators] xref: GO:0043325 is_a: CCO:F0005562 ! phosphoinositide binding [Term] id: CCO:F0005837 name: 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:kd, PMID:9045837] comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. synonym: "2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] xref: GO:0043333 is_a: CCO:F0001892 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [Term] id: CCO:F0005838 name: 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:kd, PMID:9083048] comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. synonym: "2-hexaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] xref: GO:0043334 is_a: CCO:F0001892 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [Term] id: CCO:F0005839 name: site-specific telomere resolvase activity namespace: molecular_function def: "Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases." [GOC:jl, PMID:11804598] comment: Note that while this enzyme uses a similar reaction chemistry to topoisomerases and site-specific recombinases, it performs a unique reaction. Topoisomerases promote breakage and reunion of either one or two DNA strands to alter the topological state of a DNA molecule. Site-specific recombinases perform a more complex reaction in which four strands are broken and subsequently joined to a different DNA duplex, resulting in the production of a recombinant product. The telomere resolvases on the other hand, must break two phosphodiester bonds in a single DNA duplex (one on each strand) and join each end with the opposite DNA strand to form covalently closed hairpin telomeres. synonym: "ResT" NARROW [] synonym: "TelN" NARROW [] xref: GO:0043336 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0005840 name: CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin)." [GOC:jl] synonym: "cardiolipin synthase" BROAD [] synonym: "cardiolipin synthetase" BROAD [] xref: GO:0043337 is_a: CCO:F0004483 ! phosphatidyltransferase activity [Term] id: CCO:F0005841 name: CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase namespace: molecular_function def: "Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol." [GOC:jl, PMID:10960477] synonym: "CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase" BROAD [] xref: EC:2.7.7.- xref: GO:0043338 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0005842 name: catalysis of free radical formation namespace: molecular_function def: "Catalysis of a reaction that generates a free radical, a highly reactive molecule with an unsatisfied electron valence pair." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: goslim_pir synonym: "catalysis of free radical generation" EXACT [] synonym: "catalysis of free-radical biosynthesis" EXACT [] synonym: "catalysis of free-radical formation" EXACT [] synonym: "catalysis of free-radical generation" EXACT [] xref: GO:0043364 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0005844 name: proteoglycan binding namespace: molecular_function def: "Interacting selectively with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0043394 is_a: CCO:F0000251 ! glycoprotein binding [Term] id: CCO:F0005845 name: heparan sulfate proteoglycan binding namespace: molecular_function def: "Interacting selectively with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "heparin proteoglycan binding" RELATED [] xref: GO:0043395 is_a: CCO:F0005844 ! proteoglycan binding [Term] id: CCO:F0005846 name: HLH domain binding namespace: molecular_function def: "Interacting selectively with Helix Loop Helix, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization." [GOC:go_curators, Prosite:PDOC0038] xref: GO:0043398 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0005847 name: tRNA A64-2'-O-ribosylphosphate transferase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA." [GOC:jl, UniProtKB:P23796] synonym: "initiator tRNA phosphoribosyl-transferase activity" EXACT [] xref: GO:0043399 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0005848 name: corticotropin-releasing hormone receptor activity namespace: molecular_function def: "Combining with corticotropin-releasing hormone to initiate a change in cell activity." [ISBN:0838577016, PMID:11027914, PMID:15134857] xref: GO:0043404 is_a: CCO:F0001226 ! receptor activity is_a: CCO:F0008107 ! corticotropin-releasing hormone binding [Term] id: CCO:F0005849 name: myopalladin binding namespace: molecular_function def: "Interacting selectively with myopalladin, a myofibrillar protein with titin-like Ig domains." [GOC:go_curators] xref: GO:0043411 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0005850 name: protein kinase B binding namespace: molecular_function def: "Interacting selectively with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism." [GOC:jl, http://www.heartandmetabolism.org/] synonym: "Akt binding" EXACT [] synonym: "PKB binding" EXACT [] xref: GO:0043422 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0005851 name: 3-phosphoinositide-dependent protein kinase binding namespace: molecular_function def: "Interacting selectively with a 3-phosphoinositide-dependent protein kinase." [GOC:jl] xref: GO:0043423 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0005852 name: protein histidine kinase binding namespace: molecular_function def: "Interacting selectively with protein histidine kinase." [GOC:jl] synonym: "histidine kinase binding" EXACT [] synonym: "histidine-protein kinase binding" EXACT [] synonym: "protein-histidine kinase binding" EXACT [] xref: GO:0043424 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0005853 name: bHLH transcription factor binding namespace: molecular_function def: "Interacting selectively with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transciptional networks of many developmental pathways." [PMID:9144210] xref: GO:0043425 is_a: CCO:F0001738 ! transcription factor binding [Term] id: CCO:F0005854 name: MRF binding namespace: molecular_function def: "Interacting selectively with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of trascription factors." [PMID:10966875] xref: GO:0043426 is_a: CCO:F0005853 ! bHLH transcription factor binding [Term] id: CCO:F0005855 name: 2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838] comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. synonym: "2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] xref: GO:0043428 is_a: CCO:F0001892 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [Term] id: CCO:F0005856 name: 2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838] comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. synonym: "2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] xref: GO:0043429 is_a: CCO:F0001892 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [Term] id: CCO:F0005857 name: 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838] comment: Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used. synonym: "2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [] xref: GO:0043430 is_a: CCO:F0001892 ! 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity [Term] id: CCO:F0005858 name: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine." [GOC:jl, PMID:11583838, PMID:1479344] synonym: "2-octaprenyl-6-hydroxy phenol methylase activity" EXACT [] synonym: "3-demethylubiquinone-9 3-methyltransferase activity" EXACT [] xref: GO:0043431 is_a: CCO:F0001758 ! O-methyltransferase activity [Term] id: CCO:F0005859 name: IgD binding namespace: molecular_function def: "Interacting selectively with an immunoglobulin of a D isotype." [PMID:12886015] xref: GO:0043472 is_a: CCO:F0004198 ! immunoglobulin binding [Term] id: CCO:F0005860 name: ATPase activity, coupled to movement of substances namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of a substance." [GOC:jl] subset: gosubset_prok xref: GO:0043492 is_a: CCO:F0005696 ! ATPase activity, coupled [Term] id: CCO:F0005861 name: protein anchor namespace: molecular_function def: "Interacting selectively with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane." [GOC:go_curators] synonym: "anchoring" RELATED [] xref: GO:0043495 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005862 name: cell surface binding namespace: molecular_function def: "Interacting selectively with any component on the surface of a cell." [GOC:jl] subset: goslim_pir subset: gosubset_prok xref: GO:0043498 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005863 name: eukaryotic cell surface binding namespace: molecular_function def: "Interacting selectively with any component on the surface of a eukaryotic cell." [GOC:jl] xref: GO:0043499 is_a: CCO:F0005862 ! cell surface binding [Term] id: CCO:F0005864 name: kinetochore binding namespace: molecular_function def: "Interacting selectively with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached." [GOC:jl, http://www.mercksource.com/] xref: GO:0043515 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0005865 name: leucine zipper domain binding namespace: molecular_function def: "Interacting selectively with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns." [GOC:jl, InterPro:IPR002158] synonym: "leucine zipper binding" EXACT [] xref: GO:0043522 is_a: CCO:F0004371 ! LRR domain binding [Term] id: CCO:F0005866 name: adenosine 5'-monophosphoramidase activity namespace: molecular_function def: "Catalysis of the reaction: AMP-NH2 (adenosine 5'-monophosphoramidate) = AMP + NH2. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester." [PMID:11805111] synonym: "adenosine 5' monophosphoramidase activity" EXACT [] synonym: "adenosine 5'-monophosphoramidate hydrolase activity" EXACT [] xref: GO:0043530 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005867 name: ADP binding namespace: molecular_function def: "Interacting selectively with ADP, adenosine 5'-diphosphate." [GOC:jl] synonym: "adenosine 5'-diphosphate binding" EXACT [] synonym: "adenosine diphosphate binding" EXACT [] xref: GO:0043531 is_a: CCO:F0005022 ! adenyl ribonucleotide binding [Term] id: CCO:F0005868 name: angiostatin binding namespace: molecular_function def: "Interacting selectively with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis." [PMID:16043488] xref: GO:0043532 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005869 name: inositol 1,3,4,5 tetrakisphosphate binding namespace: molecular_function def: "Interacting selectively with inositol 1,3,4,5 tetrakisphosphate." [GOC:go_curators] subset: gosubset_prok synonym: "InsP4 binding" EXACT [] synonym: "IP4 binding" EXACT [] xref: GO:0043533 is_a: CCO:F0005812 ! alcohol binding [Term] id: CCO:F0005870 name: protein serine/threonine kinase activator activity namespace: molecular_function def: "Increases the activity of a protein serine/threonine kinase." [GOC:go_curators] synonym: "protein ser/thr kinase activator activity" EXACT [] xref: GO:0043539 is_a: CCO:F0004382 ! protein kinase activator activity [Term] id: CCO:F0005871 name: lipoamide binding namespace: molecular_function def: "Interacting selectively with lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group." [GOC:go_curators] xref: GO:0043544 is_a: CCO:F0004659 ! lipoic acid binding [Term] id: CCO:F0005872 name: molybdopterin cofactor binding namespace: molecular_function def: "Interacting selectively with the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands." [ISSN:09498257] synonym: "Moco binding" EXACT [] xref: GO:0043546 is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0005873 name: phosphoinositide 3-kinase binding namespace: molecular_function def: "Interacting selectively with a phosphoinositide 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring." [PMID:10209156, PMID:9255069] xref: GO:0043548 is_a: CCO:F0004209 ! kinase binding [Term] id: CCO:F0005874 name: insulin binding namespace: molecular_function def: "Interacting selectively with insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0043559 is_a: CCO:F0003529 ! peptide hormone binding [Term] id: CCO:F0005875 name: insulin receptor substrate binding namespace: molecular_function def: "Interacting selectively with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex." [PMID:12829233] synonym: "insulin receptor substrate [protein] binding" EXACT [] synonym: "IRS [protein] binding" EXACT [] synonym: "IRS binding" EXACT [] xref: GO:0043560 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005876 name: odorant transporter activity namespace: molecular_function def: "Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of, within or between cells." [GOC:jl] subset: gosubset_prok xref: GO:0043563 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0005877 name: sequence-specific DNA binding namespace: molecular_function def: "Interacting selectively with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding." [GOC:jl] subset: gosubset_prok synonym: "sequence specific DNA binding" EXACT [] xref: GO:0043565 is_a: CCO:F0000274 ! DNA binding [Term] id: CCO:F0005878 name: structure-specific DNA binding namespace: molecular_function def: "Interacting selectively with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding." [GOC:jl] subset: gosubset_prok synonym: "structure specific DNA binding" EXACT [] xref: GO:0043566 is_a: CCO:F0000274 ! DNA binding [Term] id: CCO:F0005879 name: protein self-association namespace: molecular_function def: "Interacting selectively with a domain within the same polypeptide." [GOC:jl] synonym: "intramolecular protein binding" EXACT [] synonym: "protein self association" EXACT [] synonym: "protein self binding" EXACT [] xref: GO:0043621 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0005880 name: copper-transporting ATPase activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+ = ADP + phosphate + Cu2+, directly driving the transport of the copper ions across a membrane." [GOC:jl] subset: gosubset_prok xref: GO:0043682 is_a: CCO:F0001598 ! copper ion transmembrane transporter activity is_a: CCO:F0003011 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Term] id: CCO:F0005881 name: 2-hydroxyisocaproate CoA-transferase namespace: molecular_function def: "Catalysis of the reaction: 2-oxoisocaproate + CoA = (R)-2-hydroxyisocaproyl-CoA." [PMID:16957230] synonym: "(R)-2-hydroxyisocaproate CoA transferase activity" EXACT [] synonym: "(R)-2-hydroxyisocaproate CoA-transferase activity" EXACT [] xref: GO:0043712 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0005884 name: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity namespace: molecular_function def: "Catalysis of the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)." [UniProt:Q81MJ2] comment: This function is part of the process of methionine salvage. subset: gosubset_prok synonym: "DK-MTP-1-P enolase activity" EXACT [] synonym: "E-1" RELATED [] synonym: "MasA" RELATED [] synonym: "mtnW" RELATED [] xref: EC:5.3.2.- xref: GO:0043715 xref: MetaCyc:R82-RXN is_a: CCO:F0003424 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups [Term] id: CCO:F0005885 name: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity namespace: molecular_function def: "Cataysis of the dephosphorylation of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-P) to 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)." [IMG:01681, UniProt:O31667] subset: gosubset_prok synonym: "HK-MTPenyl-1-P phosphatase activity" EXACT [] xref: GO:0043716 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005886 name: 2-hydroxyglutaryl-CoA dehydratase activity namespace: molecular_function def: "Catalysis of the dehydration of 2-hydroxyglutaryl-CoA to glutaconyl-CoA." [UniProt:P11569] subset: gosubset_prok synonym: "(R)-2-hydroxyglutaryl-CoA dehydratase activity" EXACT [] xref: GO:0043717 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005887 name: 2-hydroxymethylglutarate dehydrogenase namespace: molecular_function def: "Catalysis of the reaction: (S)-2-hydroxymethylglutarate + NAD+ = 2-formylglutarate + NADH + H+." [EC:1.1.1.291] subset: gosubset_prok synonym: "(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.291] synonym: "HgD" EXACT [] xref: EC:1.1.1.291 xref: GO:0043718 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005888 name: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase namespace: molecular_function def: "Catalysis of the introduction of a hydroxyl group at carbon five of 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol to form 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol." [GOC:jl, UniProt:P75728] subset: gosubset_prok xref: EC:1.14.13.- xref: GO:0043719 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005889 name: 3-keto-5-aminohexanoate cleavage activity namespace: molecular_function def: "Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate." [PMID:13064] subset: gosubset_prok synonym: "3-keto-5-aminohexanoate cleavage enzyme" EXACT [] xref: GO:0043720 xref: MetaCyc:R125-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005890 name: 4-hydroxybutyryl-CoA dehydratase activity namespace: molecular_function def: "Catalysis of the formation of vinylacetyl-CoA from 4-hydroxybutyryl-CoA." [http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "gamma-hydroxybutyryl-CoA dehydratase activity" EXACT [] xref: EC:4.2.1.- xref: GO:0043721 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005891 name: 4-hydroxyphenylacetate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: (4-hydroxyphenyl)acetate + H+ = 4-methylphenol + CO2." [EC:4.1.1.83] subset: gosubset_prok synonym: "4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)" EXACT [EC:4.1.1.83] synonym: "4-Hpd activity" EXACT [EC:4.1.1.83] synonym: "4-hydroxyphenylacetate carboxy-lyase activity" EXACT [EC:4.1.1.83] synonym: "p-Hpd activity" EXACT [EC:4.1.1.83] synonym: "p-hydroxyphenylacetate decarboxylase activity" EXACT [EC:4.1.1.83] xref: EC:4.1.1.83 xref: GO:0043722 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0005892 name: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase namespace: molecular_function def: "Catalysis of the reaction: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate + NH3." [PMID:11889103] subset: gosubset_prok synonym: "2,5-diamino-6-(5-phosphoribitylamino)pyrimidin-4(3H)-one deaminase activity" EXACT [] xref: EC:3.5.4.- xref: GO:0043723 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [Term] id: CCO:F0005893 name: 2-keto-3-deoxygalactonate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate." [PMID:12824170] subset: gosubset_prok synonym: "KDGal aldolase activity" EXACT [] xref: EC:4.2.1.- xref: GO:0043724 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005894 name: 2-keto-3-deoxygluconate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-keto-3-deoxygluconate = D-glyceraldehyde + pyruvate." [PMID:12824170] subset: gosubset_prok synonym: "KDG aldolase activity" EXACT [] xref: EC:4.2.1.- xref: GO:0043725 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005895 name: 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate." [GOC:jl, IMG:01282] subset: gosubset_prok xref: EC:3.1.3.- xref: GO:0043726 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005896 name: 5-amino-4-imidazole carboxylate lyase activity namespace: molecular_function def: "Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate." [GOC:jl, IMG:01835] subset: gosubset_prok xref: EC:4.1.1.- xref: GO:0043727 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0005897 name: 2-keto-4-methylthiobutyrate aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine." [GOC:jl, IMG:01683] subset: gosubset_prok xref: EC:4.1.1.- xref: GO:0043728 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005898 name: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate." [GOC:jl, IMG:01536] subset: gosubset_prok xref: EC:4.-.-.- xref: GO:0043729 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0005899 name: 5-ureido-4-imidazole carboxylate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2." [GOC:jl, IMG:02121] subset: gosubset_prok xref: EC:3.5.3.- xref: GO:0043730 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0005900 name: 6-hydroxynicotinate 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD." [GOC:jl, PMID:10091591] subset: gosubset_prok xref: EC:1.14.13.- xref: GO:0043731 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005901 name: 6-hydroxynicotinate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 6-hydroxynicotinate + H2O + O2 = 2,6-dihydroxynicotinate + H2O." [EC:1.17.3.3] subset: gosubset_prok synonym: "6-hydroxynicotinate hydroxylase activity" EXACT [EC:1.17.3.3] synonym: "6-hydroxynicotinate:O2 oxidoreductase activity" EXACT [EC:1.17.3.3] synonym: "6-hydroxynicotinic acid dehydrogenase activity" EXACT [EC:1.17.3.3] synonym: "6-hydroxynicotinic acid hydroxylase activity" EXACT [EC:1.17.3.3] xref: EC:1.17.3.3 xref: GO:0043732 is_a: CCO:F0003309 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor [Term] id: CCO:F0005902 name: DNA-3-methyladenine glycosylase III activity namespace: molecular_function def: "Catalysis of the hydrolysis of alkylated DNA; recognizes and removes alkylated 3-methylpurines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site." [IMG:00576, PMID:10777493, PMID:14517230] subset: gosubset_prok synonym: "Mag III" NARROW [] synonym: "MagIII" NARROW [] xref: EC:3.2.2.- xref: GO:0043733 xref: IMG:00576 is_a: CCO:F0000410 ! alkylbase DNA N-glycosylase activity [Term] id: CCO:F0005903 name: DNA-N1-methyladenine dioxygenase activity namespace: molecular_function def: "Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA and RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methylgroup on N1-methyladenine and N3-methylcytosine as formaldehyde." [IMG:00579, UniProt:P05050] subset: gosubset_prok synonym: "AlkB" NARROW [] synonym: "alkB" NARROW [] synonym: "alpha-ketoglutarate-dependent dioxygenase" NARROW [] xref: EC:1.14.11.- xref: GO:0043734 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0005904 name: delta-9 acyl-phospholipid desaturase activity namespace: molecular_function subset: gosubset_prok synonym: "MpgII" NARROW [] xref: GO:0043735 is_a: CCO:F0003300 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Term] id: CCO:F0005905 name: DNA-3-methyladenine glycosylase IV activity namespace: molecular_function def: "Catalysis of the hydrolysis of alkylated DNA; recognizes and removes both N-3- and N-7-methyl purines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site." [IMG:00578, PMID:10375529] subset: gosubset_prok synonym: "Mpg II" NARROW [] synonym: "MpgII" NARROW [] xref: EC:3.2.2.- xref: GO:0043736 xref: IMG:00578 is_a: CCO:F0000410 ! alkylbase DNA N-glycosylase activity [Term] id: CCO:F0005906 name: deoxyribonuclease V activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate." [EC:3.1.21.7] synonym: "DNase V activity" EXACT [EC:3.1.21.7] synonym: "endodeoxyribonuclease V" EXACT [] synonym: "endonuclease V activity" BROAD [EC:3.1.21.7] synonym: "Escherichia coli endodeoxyribonuclease V activity" NARROW [EC:3.1.21.7] xref: EC:3.1.21.7 xref: GO:0043737 is_a: CCO:F0003446 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005907 name: F420H2 dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: methanophenazine + reduced cofactor F420 = dihydromethanophenazine + cofactor F420." [MetaCyc:CPLX-7105] subset: gosubset_prok xref: EC:1.-.-.- xref: GO:0043738 xref: MetaCyc:CPLX-7105 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0005908 name: G/U mismatch-specific uracil-DNA glycosylase activity namespace: molecular_function def: "Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site." [IMG:00570, SP:O59825] subset: gosubset_prok synonym: "GU mismatch-specific uracil-DNA glycosylase activity" EXACT [] synonym: "MUG" EXACT [] synonym: "uracil mismatch repair protein" BROAD [] xref: GO:0043739 is_a: CCO:F0001200 ! uracil DNA N-glycosylase activity is_a: CCO:F0001804 ! pyrimidine-specific mismatch base pair DNA N-glycosylase activity [Term] id: CCO:F0005909 name: GTP cyclohydrolase IIa activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 3 H2O = 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + 2 phosphate." [EC:3.5.4.29] subset: gosubset_prok synonym: "GTP 8,9-dihydrolase (phosphate-forming)" EXACT [EC:3.5.4.29] synonym: "GTP 8,9-hydrolase (phosphate-forming)" EXACT [] synonym: "GTP cyclohydrolase III activity" NARROW [EC:3.5.4.29] xref: EC:3.5.4.29 xref: GO:0043740 is_a: CCO:F0000428 ! GTP cyclohydrolase activity [Term] id: CCO:F0005910 name: L-2-aminoadipate N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-aminoadipate + acetyl-CoA = N2-acetyl-L-aminoadipate + CoA." [IMG:01447] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0043741 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0005911 name: LPPG:FO 2-phospho-L-lactate transferase activity namespace: molecular_function def: "Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP." [IMG:01551] subset: gosubset_prok xref: EC:2.7.1.- xref: GO:0043743 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0005912 name: N2-acetyl-L-aminoadipate kinase activity namespace: molecular_function def: "Catalysis of the reaction: N2-acetyl-L-aminoadipate + ATP = N2-acetyl-L-aminoadipyl-delta-phosphate + ADP." [IMG:01448] subset: gosubset_prok xref: EC:2.7.2.- xref: GO:0043744 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0005913 name: N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate." [IMG:01449] subset: gosubset_prok xref: EC:1.2.1.- xref: GO:0043745 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005914 name: N2-acetyl-L-lysine aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine." [IMG:01450] subset: gosubset_prok synonym: "N-acetyl-lysine aminotransferase activity" EXACT [] xref: EC:2.6.1.- xref: GO:0043746 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005915 name: N2-acetyl-L-lysine deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine." [IMG:01451] subset: gosubset_prok synonym: "N-acetyl-lysine deacetylase activity" EXACT [] xref: EC:3.5.1.- xref: GO:0043747 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005916 name: O-succinylbenzoate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate." [IMG:01733] subset: gosubset_prok xref: EC:3.5.1.- xref: GO:0043748 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005917 name: phenol, water dikinase activity namespace: molecular_function def: "Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate." [PMID:15547277] subset: gosubset_prok synonym: "ATP:phenol:water phosphotransferase activity" EXACT [] synonym: "phenol:water dikinase activity" EXACT [] synonym: "phenylphosphate synthase activity" EXACT [] xref: EC:2.7.9.- xref: GO:0043749 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003353 ! phosphotransferase activity, paired acceptors [Term] id: CCO:F0005918 name: phosphatidylinositol alpha-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol." [EC:2.4.1.57] subset: gosubset_prok synonym: "GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity" EXACT [EC:2.4.1.57] synonym: "GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.57] synonym: "GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.57] synonym: "GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.57] synonym: "guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase activity" EXACT [EC:2.4.1.57] synonym: "phosphatidyl-myo-inositol alpha-mannosyltransferase activity" EXACT [EC:2.4.1.57] xref: EC:2.4.1.57 xref: GO:0043750 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0005919 name: polyphosphate:AMP phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP." [http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "PAP" EXACT [] synonym: "PPT" EXACT [] xref: EC:2.7.4.- xref: GO:0043751 is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0005920 name: adenosylcobinamide kinase activity namespace: molecular_function def: "Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP)." [EC:2.7.1.156] subset: gosubset_prok synonym: "adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase" BROAD [] synonym: "AdoCbi kinase/AdoCbi-phosphate guanylyltransferase" BROAD [] synonym: "CobU" RELATED [] synonym: "RTP:adenosylcobinamide phosphotransferase activity" EXACT [] xref: EC:2.7.1.156 xref: GO:0043752 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0005921 name: adenosylcobinamide-phosphate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + adenosylcobinamide phosphate = diphosphate + adenosylcobinamide-GDP." [EC:2.7.7.62] subset: gosubset_prok synonym: "adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase" BROAD [] synonym: "AdoCbi kinase/AdoCbi-phosphate guanylyltransferase" BROAD [] synonym: "CobU" RELATED [] synonym: "GTP:adenosylcobinamide-phosphate guanylyltransferase activity" EXACT [] xref: EC:2.7.7.62 xref: GO:0043753 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0005922 name: dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine." [EC:2.3.1.168] subset: gosubset_prok synonym: "2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity" EXACT [EC:2.3.1.168] synonym: "2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity" EXACT [EC:2.3.1.168] synonym: "dihydrolipoyl transacylase activity" EXACT [EC:2.3.1.168] synonym: "enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity" EXACT [] xref: EC:2.3.1.168 xref: GO:0043754 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005923 name: alpha-ribazole phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate." [EC:3.1.3.73] subset: gosubset_prok synonym: "alpha-ribazole-5'-phosphate phosphohydrolase activity" EXACT [] synonym: "CobC" RELATED [] xref: EC:3.1.3.73 xref: GO:0043755 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0005924 name: adenosylcobinamide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: adenosylcobinamide + H2O = adenosylcobyric acid + (R)-1-aminopropan-2-ol." [EC:3.5.1.90] subset: gosubset_prok synonym: "adenosylcobinamide amidohydrolase activity" EXACT [EC:3.5.1.90] synonym: "AdoCbi amidohydrolase activity" EXACT [EC:3.5.1.90] synonym: "AdoCbi hydrolase activity" EXACT [EC:3.5.1.90] synonym: "CbiZ" RELATED [] xref: EC:3.5.1.90 xref: GO:0043756 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0005925 name: adenosylcobinamide-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reactions: (1) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate and (2) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide." [EC:6.3.1.10] subset: gosubset_prok synonym: "adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)" EXACT [] synonym: "AdoCbi-P synthase activity" EXACT [EC:6.3.1.10] synonym: "CbiB" RELATED [] xref: EC:6.3.1.10 xref: GO:0043757 is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0005926 name: acetate-CoA ligase (ADP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA." [EC:6.2.1.13] subset: gosubset_prok synonym: "acetate thiokinase activity" BROAD [EC:6.2.1.13] synonym: "acetate--CoA ligase (ADP-forming) activity" EXACT [] synonym: "acetate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.13] synonym: "acetyl coenzyme A synthetase (adenosine diphosphate-forming)" EXACT [] synonym: "acetyl-CoA synthetase (ADP-forming) activity" EXACT [EC:6.2.1.13] xref: EC:6.2.1.13 xref: GO:0043758 is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0005927 name: branched-chain acyl-CoA synthetase (ADP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = ADP + orthophosphate + 2-methylbutanoyl-CoA." [IMG:01425] subset: gosubset_prok synonym: "branched chain acyl CoA synthetase (ADP-forming) activity" EXACT [] synonym: "branched chain acyl-CoA synthetase (ADP-forming) activity" EXACT [] synonym: "branched-chain acyl CoA synthetase (ADP-forming) activity" EXACT [] xref: EC:6.2.1.- xref: GO:0043759 is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0005928 name: acetyldiaminopimelate aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate." [IMG:00444, PMID:1906065] subset: gosubset_prok synonym: "N-acetyl-diaminopimelate aminotransferase activity" EXACT [] synonym: "N-acetyl-L,L-diaminopimelate aminotransferase activity" EXACT [] xref: EC:2.6.1.- xref: GO:0043760 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005929 name: archaetidylserine synthase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP." [IMG:01567, PMID:12562787] subset: gosubset_prok synonym: "CDP-2,3-di-O-geranylgeranyl-sn-glycerol inositol 1-archaetidyltransferase activity" EXACT [] synonym: "CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity" EXACT [] xref: EC:2.7.8.- xref: GO:0043761 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0005930 name: aryl-CoA synthetase (ADP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: ATP + phenylacetate + CoA = ADP + orthophosphate + phenylacetyl-CoA." [IMG:01427] subset: gosubset_prok xref: EC:6.2.1.- xref: GO:0043762 is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0005931 name: UTP:glucose-1-phosphate uridylyltransferase regulator activity namespace: molecular_function def: "Modulates the activity of UTP:glucose-1-phosphate uridylyltransferase." [GOC:jl] subset: gosubset_prok synonym: "glucose-1-phosphate uridylyltransferase regulator activity" EXACT [] synonym: "UDP-glucose diphosphorylase regulator activity" EXACT [] synonym: "UDP-glucose pyrophosphorylase regulator activity" EXACT [] xref: GO:0043763 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0005932 name: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] = UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl carrier protein]." [IMG:00545, InterPro:IPR007691] subset: gosubset_prok xref: EC:2.3.1.- xref: GO:0043764 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005933 name: T/G mismatch-specific endonuclease activity namespace: molecular_function def: "Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine." [IMG:00606, SP:P09184] subset: gosubset_prok synonym: "DNA mismatch endonuclease" BROAD [] synonym: "V.EcoKDcm" RELATED [] synonym: "very short patch repair protein" RELATED [] synonym: "Vsr mismatch endonuclease" RELATED [] xref: EC:3.1.-.- xref: GO:0043765 is_a: CCO:F0000916 ! endonuclease activity [Term] id: CCO:F0005934 name: Sep-tRNA:Cys-tRNA synthase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoseryl-tRNA(Cys) + H2S = cysteinyl-tRNA(Cys) + orthophosphate." [IMG:00235, PMID:15790858, PMID:16380427, PMID:17110438] subset: gosubset_prok synonym: "O-phosphoseryl-tRNA:cysteinyl-tRNA synthase activity" EXACT [] synonym: "Sep-tRNA:Cys-tRNA synthetase activity" EXACT [] synonym: "SepCysS" RELATED [] xref: EC:2.5.1.- xref: GO:0043766 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005935 name: pyrrolysyl-tRNA synthetase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + pyrophosphate + L-pyrrolysyl-tRNA(Pyl)." [IMG:02553, PMID:15314242, SP:Q8TUB8] subset: gosubset_prok synonym: " Pyrrolysine-tRNA ligase activity" EXACT [] synonym: "PylRS" EXACT [] xref: EC:6.1.1.- xref: GO:0043767 is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0005936 name: S-ribosylhomocysteine lyase activity namespace: molecular_function def: "Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (S)-4,5-dihydroxypentan-2,3-dione." [EC:4.4.1.21, IMG:02085] subset: gosubset_prok synonym: "3.2.1.148" RELATED [] synonym: "LuxS" RELATED [] synonym: "ribosylhomocysteinase activity" EXACT [] synonym: "S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming]" RELATED [EC:4.4.1.21] synonym: "S-ribosylhomocysteinase activity" EXACT [] xref: EC:4.4.1.21 xref: GO:0019138 xref: GO:0043768 xref: MetaCyc:RIBOSYLHOMOCYSTEINASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0005937 name: demethylmenaquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine." [IMG:01848] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0043770 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005938 name: cytidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + cytidine = ADP + CMP." [IMG:01870] subset: gosubset_prok xref: EC:2.7.1.- xref: GO:0043771 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0005939 name: acyl-phosphate glycerol-3-phosphate acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate." [IMG:01872, PMID:17308305] subset: gosubset_prok synonym: "acyl-phosphate:glycerol-3-phosphate acyltransferase activity" EXACT [] synonym: "acylphosphate glycerol-3-phosphate acyltransferase activity" EXACT [] synonym: "acylphosphate:glycerol-3-phosphate acyltransferase activity" EXACT [] xref: GO:0043772 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0005940 name: coenzyme F420-0 gamma-glutamyl ligase activity namespace: molecular_function def: "Catalyzes the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates, i.e. GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1 followed by GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2." [IMG:01552, UniProt:Q58178] subset: gosubset_prok synonym: "F420-0 gamma-glutamyl ligase activity" EXACT [] xref: EC:6.3.2.- xref: GO:0043773 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0005941 name: coenzyme F420-2 alpha-glutamyl ligase activity namespace: molecular_function def: "Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate." [IMG:01553] subset: gosubset_prok synonym: "F420-2 alpha-glutamyl ligase activity" EXACT [] xref: EC:6.3.2.- xref: GO:0043774 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0005942 name: cobyrinate a,c-diamide synthase activity namespace: molecular_function def: "Catalysis of the reaction: cobyrinate + 2 L-glutamine + 2 ATP + 2 H2O = cob(II)yrinate a,c-diamide + 2 L-glutamate + 2 ADP + 2 orthophosphate." [IMG:01814] subset: gosubset_prok synonym: "cobyrinate a c diamide synthase activity" EXACT [] synonym: "cobyrinate a c-diamide synthase activity" EXACT [] synonym: "cobyrinate a,c diamide synthase activity" EXACT [] xref: EC:6.3.5.- xref: GO:0043775 is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0005943 name: cobalt-precorrin-6B C5-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7." [IMG:02115, MetaCyc:RXN-8766] subset: gosubset_prok synonym: "cobalt-precorrin 6B C5-methyltransferase activity" EXACT [] synonym: "precorrin-6 methyltransferase activity" EXACT [] synonym: "precorrin-6Y C5,15-methyltransferase (decarboxylating)" BROAD [] synonym: "precorrin-6Y methylase" BROAD [] xref: EC:2.1.1.- xref: GO:0043776 xref: MetaCyc:RXN-8766 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005944 name: cobalt-precorrin-7 C15-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2." [IMG:02116, MetaCyc:RXN-8767] subset: gosubset_prok synonym: "cobalt-precorrin 7 C15-methyltransferase activity" EXACT [] synonym: "precorrin-6 methyltransferase" BROAD [] synonym: "precorrin-6Y C5,15-methyltransferase (decarboxylating)" BROAD [] synonym: "precorrin-6Y methylase" BROAD [] xref: EC:2.1.1.- xref: GO:0043777 xref: MetaCyc:RXN-8767 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005945 name: cobalt-precorrin-8 methylmutase activity namespace: molecular_function def: "Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate." [IMG:02117, MetaCyc:RXN-8768] subset: gosubset_prok synonym: "cobalt-precorrin 8 methylmutase activity" EXACT [] synonym: "cobalt-precorrin 8X methylmutase activity" EXACT [] synonym: "cobalt-precorrin-8X methylmutase activity" EXACT [] xref: EC:5.4.1.- xref: GO:0043778 xref: MetaCyc:RXN-8768 is_a: CCO:F0003428 ! intramolecular transferase activity, transferring acyl groups [Term] id: CCO:F0005946 name: cobalt-precorrin-5A acetaldehyde-lyase activity namespace: molecular_function def: "Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde." [IMG:02112, MetaCyc:RXN-8763] subset: gosubset_prok synonym: "cobalt-precorrin 5A acetaldehyde-lyase activity" EXACT [] xref: GO:0043779 xref: MetaCyc:RXN-8763 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0005947 name: cobalt-precorrin-5B C1-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A." [IMG:02112, MetaCyc:RXN-8764] subset: gosubset_prok synonym: "cobalt-precorrin 5B C1-methyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0043780 xref: MetaCyc:RXN-8764 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005948 name: cobalt-factor II C20-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III." [EC:2.1.1.151, IMG:01812] subset: gosubset_prok synonym: "CbiL" NARROW [] synonym: "cobalt-factor II C20 methyltransferase activity" EXACT [] synonym: "cobalt-precorrin-2 C(20)-methyltransferase activity" EXACT [EC:2.1.1.151] synonym: "S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase activity" EXACT [EC:2.1.1.151] xref: EC:2.1.1.151 xref: GO:0043781 xref: MetaCyc:RXN-8760 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005949 name: cobalt-precorrin-3 C17-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine." [IMG:02110, MetaCyc:RXN-8761, UniProt:Q05590] subset: gosubset_prok synonym: "cobalt-precorrin 3 C17-methyltransferase activity" EXACT [] synonym: "cobalt-precorrin-3 methylase" BROAD [] synonym: "cobalt-precorrin-3 methyltransferase" BROAD [] synonym: "cobalt-precorrin-3B C17-methyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0043782 xref: MetaCyc:RXN-8761 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005950 name: oxidoreductase activity, oxidizing metal ions with flavin as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and flavin acts as an electron acceptor." [EC:1.16.8] subset: gosubset_prok xref: EC:1.16.8 xref: GO:0043783 is_a: CCO:F0003304 ! oxidoreductase activity, oxidizing metal ions [Term] id: CCO:F0005951 name: cob(II)yrinic acid a,c-diamide reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 cob(II)yrinic acid a,c-diamide + FMN = 2 cob(I)yrinic acid a,c-diamide + FMNH2." [EC:1.16.8.1] subset: gosubset_prok synonym: "cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity" EXACT [] xref: EC:1.16.8.1 xref: GO:0043784 is_a: CCO:F0005950 ! oxidoreductase activity, oxidizing metal ions with flavin as acceptor [Term] id: CCO:F0005952 name: cinnamoyl-CoA:phenyllactate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: (E)-cinnamoyl-CoA + (R)-phenyllactate = (E)-cinnamate + (R)-phenyllactyl-CoA." [EC:2.8.3.17] subset: gosubset_prok synonym: "(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase activity" EXACT [] synonym: "FldA" RELATED [] xref: EC:2.8.3.17 xref: GO:0043785 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0005953 name: cinnamate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+." [EC:1.3.1.-, IMG:01615, PMID:10849007] subset: gosubset_prok xref: EC:1.3.1.- xref: GO:0043786 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005954 name: chlorophyll synthase activity namespace: molecular_function def: "Catalysis of the reaction: chlorophyllide a + phytyl diphosphate = chlorophyll a + diphosphate." [EC:2.5.1.62, IMG:01750] subset: gosubset_prok synonym: "chlorophyllide-a:phytyl-diphosphate phytyltransferase activity" EXACT [] xref: EC:2.5.1.62 xref: GO:0043787 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0005955 name: cardiolipin synthetase 2 activity namespace: molecular_function def: "Catalysis of the reaction: 2 1,2-diacyl-sn-glycero-3-[phospho-rac-(1-glycerol)] = cardiolipin + glycerol." [IMG:00156] subset: gosubset_prok synonym: "cardiolipin synthase 2 activity" EXACT [] xref: EC:2.7.8.- xref: GO:0043788 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0005956 name: diguanylate cyclase activity namespace: molecular_function def: "Catalysis of the conversion of 2GTP to bis-(3'-5')cyclic guanylic acid, via linear diguanosine tetraphosphate pppg 3'p5'g, releasing 1 pyrophosphate at each step." [http://cancerweb.ncl.ac.uk/, IMG:02393, PMID:16895465] subset: gosubset_prok xref: EC:4.6.1.- xref: GO:0043789 is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0005957 name: dimethyladenosine transferase activity namespace: molecular_function def: "Catalysis of the dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle." [IMG:02532, UniProt:Q6C7H6] subset: gosubset_prok synonym: "18S rRNA dimethylase activity" EXACT [] synonym: "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0043790 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005958 name: dimethylamine methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine." [IMG:01321, MetaCyc:RXN-8100, PMID:9874228, UniProt:O93661] comment: This function is the first step in the pathway of methanogenesis from dimethylamine. subset: gosubset_prok synonym: "dimethylamine:corrinoid methyltransferase activity" EXACT [] synonym: "DMA methyltransferase 1" EXACT [] synonym: "DMAMT 1" EXACT [] synonym: "MT1" BROAD [] synonym: "mtbB1" RELATED [] xref: EC:2.1.1.- xref: GO:0043791 xref: MetaCyc:RXN-8100 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005959 name: enamidase activity namespace: molecular_function def: "Catalysis of the reaction: 6-oxo-1,4,5,6-tetrahydronicotinate + 2 H2O = 2-formylglutarate + NH." [EC:3.5.2.18] subset: gosubset_prok synonym: "6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase activity" EXACT [] xref: EC:3.5.2.18 xref: GO:0043792 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0005960 name: beta-ribofuranosylaminobenzene 5'-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + pyrophosphate." [GOC:jl, IMG:01544, PMID:12142414] subset: gosubset_prok synonym: "beta-RFAP synthase activity" EXACT [] xref: GO:0043793 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0005961 name: formate dehydrogenase (F420) activity namespace: molecular_function def: "Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420." [IMG:01432, PMID:3801411] subset: gosubset_prok xref: EC:1.2.99.- xref: GO:0043794 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0005962 name: glyceraldehyde oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde + H2O + acceptor = D-glycerate + reduced acceptor." [IMG:01506] subset: gosubset_prok xref: EC:1.2.-.-. xref: GO:0043795 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0005963 name: glyceraldehyde dehydrogenase (NADP) activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+." [IMG:01555] subset: gosubset_prok xref: EC:1.2.1.- xref: GO:0043796 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005964 name: glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin." [EC:1.2.7.6] subset: gosubset_prok synonym: "D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase activity" EXACT [] synonym: "GAPOR" RELATED [] synonym: "glyceraldehyde-3-phosphate Fd oxidoreductase activity" EXACT [EC:1.2.7.6] synonym: "glyceraldehyde-3-phosphate ferredoxin reductase activity" EXACT [EC:1.2.7.6] xref: EC:1.2.7.6 xref: GO:0043797 is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0005965 name: glycerate 2-kinase activity namespace: molecular_function def: "Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP." [IMG:01510, PMID:14413719, Reactome:GKI-RXN] subset: gosubset_prok synonym: "D-glycerate 2-kinase activity" EXACT [] synonym: "glycerate kinase" BROAD [] xref: EC:2.7.1.- xref: GO:0043798 xref: MetaCyc:GKI-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003257 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor [Term] id: CCO:F0005966 name: glycine oxidase activity namespace: molecular_function def: "Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + H2O2 (2) D-alanine + H2O + O2 = pyruvate + NH3 + H2O2 (3) sarcosine + H2O + O2 = glyoxylate + methylamine + H2O2 (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + H2O2." [EC:1.4.3.19] subset: gosubset_prok synonym: "glycine:oxygen oxidoreductase (deaminating)" EXACT [] xref: EC:1.4.3.19 xref: GO:0043799 is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0005967 name: hexulose-6-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate." [IMG:01502, UniProt:P44990] subset: gosubset_prok synonym: "HUMPI" EXACT [] xref: EC:5.-.-.- xref: GO:0043800 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0005968 name: hexulose-6-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate." [IMG:01503, UniProt:Q5WCM6] subset: gosubset_prok xref: EC:4.1.2.- xref: GO:0043801 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0005969 name: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity namespace: molecular_function def: "Catalysis of the reaction: 2 ATP + hydrogenobyrinic acid + 2 L-glutamine + 2 H2O = 2 ADP + 2 phosphate + hydrogenobyrinic acid a,c-diamide + 2 L-glutamate." [EC:6.3.5.9] subset: gosubset_prok synonym: "CobB" RELATED [] synonym: "hydrogenobyrinic acid a,c diamide synthase (glutamine-hydrolysing) activity" EXACT [] synonym: "hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming)" EXACT [] xref: EC:6.3.5.9 xref: GO:0043802 is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0005970 name: hydroxyneurosporene-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = spheroidene + S-adenosyl-L-homocysteine." [IMG:01759] subset: gosubset_prok xref: EC:2.1.1.- xref: GO:0043803 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005971 name: imidazolone hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-formiminoglycine = imidazolone + H2O." [IMG:02122] subset: gosubset_prok xref: EC:3.5.2.- xref: GO:0043804 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0005972 name: indolepyruvate ferredoxin oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.8] subset: gosubset_prok synonym: "3-(indol-3-yl)pyruvate synthase (ferredoxin) activity" EXACT [EC:1.2.7.8] synonym: "3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating)" EXACT [EC:1.2.7.8] synonym: "indolepyruvate oxidoreductase activity" EXACT [EC:1.2.7.8] synonym: "IOR" RELATED [] xref: EC:1.2.7.8 xref: GO:0043805 is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0005973 name: keto acid formate lyase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate." [IMG:00725, UniProt:P42632] subset: gosubset_prok synonym: "keto-acid formate acetyltransferase" BROAD [] synonym: "keto-acid formate lyase activity" EXACT [] synonym: "keto-acid formate-lyase activity" EXACT [] xref: EC:2.3.1.- xref: GO:0043806 is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0005974 name: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.7] subset: gosubset_prok synonym: "2-ketoisovalerate ferredoxin reductase activity" EXACT [EC:1.2.7.7] synonym: "2-oxoisovalerate ferredoxin reductase activity" EXACT [EC:1.2.7.7] synonym: "3-methyl-2-oxobutanoate synthase (ferredoxin) activity" EXACT [EC:1.2.7.7] synonym: "3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylpropanoylating)" EXACT [] synonym: "branched-chain ketoacid ferredoxin reductase activity" RELATED [EC:1.2.7.7] synonym: "branched-chain oxo acid ferredoxin reductase activity" RELATED [EC:1.2.7.7] synonym: "keto-valine-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.7] synonym: "ketoisovalerate ferredoxin reductase activity" EXACT [EC:1.2.7.7] synonym: "ketoisovalerate oxidoreductase activity" EXACT [EC:1.2.7.7] synonym: "VOR" RELATED [] xref: EC:1.2.7.7 xref: GO:0043807 is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0005975 name: lyso-ornithine lipid acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl carrier protein] = ornithine lipid + [acyl carrier protein]." [IMG:02097, PMID:15341653] subset: gosubset_prok xref: GO:0043808 is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0005976 name: methylthioribulose 1-phosphate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H2O." [EC:4.2.1.109] subset: gosubset_prok synonym: "1-PMT-ribulose dehydratase activity" EXACT [EC:4.2.1.109] synonym: "methylthioribulose-1-phosphate dehydratase activity" EXACT [] synonym: "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]" RELATED [EC:4.2.1.109] synonym: "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase activity" EXACT [] synonym: "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase[5-(methylthio)-2,3-dioxopentyl-phosphate-forming]" EXACT [] xref: EC:4.2.1.109 xref: GO:0043809 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0005977 name: ornithine-acyl [acyl carrier protein] N-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl carrier protein]." [IMG:02096] subset: gosubset_prok synonym: "ornithine-acyl[acyl carrier protein] N-acyltransferase activity" EXACT [] xref: GO:0043810 is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0005978 name: phosphate:acyl-[acyl carrier protein] acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl carrier protein] + orthophosphate = acyl phosphate + [acyl carrier protein]." [IMG:01871] subset: gosubset_prok xref: GO:0043811 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0005979 name: phosphatidylinositol-4-phosphate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate." [IMG:01360] subset: gosubset_prok synonym: "phosphatidylinositol 4-phosphate phosphatase activity" EXACT [] xref: EC:3.1.3.- xref: GO:0043812 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0005980 name: phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidyInositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate." [IMG:01359, UniProt:P42837] subset: gosubset_prok synonym: "phosphatidylinositol 3,5-bisphosphate 5-phosphatase activity" EXACT [] xref: EC:3.1.3.- xref: GO:0043813 is_a: CCO:F0000843 ! phosphoinositide 5-phosphatase activity is_a: CCO:F0008466 ! phosphatidylinositol bisphosphate phosphatase activity [Term] id: CCO:F0005981 name: phospholactate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + pyrophosphate." [IMG:01547] subset: gosubset_prok xref: EC:2.7.7.- xref: GO:0043814 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0005982 name: phosphoribosylglycinamide formyltransferase 2 activity namespace: molecular_function def: "Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate." [IMG:01297, UniProt:P33221] subset: gosubset_prok synonym: "5'-phosphoribosylglycinamide transformylase 2" EXACT [] synonym: "formate-dependent GAR transformylase activity" EXACT [] synonym: "GAR transformylase 2" RELATED [] synonym: "GART 2" RELATED [] xref: EC:2.1.2.- xref: GO:0043815 is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0005983 name: phosphoserine-tRNA(Cys) ligase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + pyrophosphate + phosphoseryl-tRNA(Cys)." [IMG:00622, PMID:17110438] subset: gosubset_prok synonym: "O-phosphoseryl-tRNA(Cys) synthetase activity" EXACT [] synonym: "phosphoserine--tRNA(Cys) ligase activity" EXACT [] synonym: "phosphoserine-tRNACys ligase activity" EXACT [] synonym: "SepRS" RELATED [] xref: EC:6.1.1.- xref: GO:0043816 is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0005984 name: phosphosulfolactate synthase activity namespace: molecular_function def: "Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = sulfite + phosphoenolpyruvate." [IMG:00622] subset: gosubset_prok synonym: "(2R)-O-phospho-3-sulfolactate sulfo-lyase (phosphoenolpyruvate-forming)" EXACT [EC:4.4.1.19] synonym: "(2R)-O-phospho-3-sulfolactate sulfo-lyase activity" EXACT [] synonym: "(2R)-phospho-3-sulfolactate synthase activity" EXACT [EC:4.4.1.19] synonym: "PSL synthase activity" EXACT [EC:4.4.1.19] xref: EC:4.4.1.19 xref: GO:0043817 is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0005985 name: precorrin-3B synthase activity namespace: molecular_function def: "Catalysis of the reaction: precorrin-3A + NADH + H+ + O2 = precorrin-3B + NAD+ + H2O." [IMG:01805] subset: gosubset_prok synonym: "CobG" RELATED [] synonym: "precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)" EXACT [] synonym: "precorrin-3X synthase activity" EXACT [EC:1.14.13.83] xref: EC:1.14.13.83 xref: GO:0043818 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0005986 name: precorrin-6A synthase (deacetylating) activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-5 + H2O = S-adenosyl-L-homocysteine + precorrin-6A + acetate." [EC:2.1.1.152, IMG:01802] subset: gosubset_prok synonym: "CobF" RELATED [] synonym: "precorrin-6X synthase (deacetylating) activity" EXACT [EC:2.1.1.152] synonym: "S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating)" EXACT [] xref: EC:2.1.1.152 xref: GO:0043819 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0005987 name: propionyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA." [PMID:12603323] subset: gosubset_prok xref: EC:1.3.99.- xref: GO:0043820 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0005988 name: propionyl-CoA:succinate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate." [IMG:01589, MetaCyc:RXN0-268] subset: gosubset_prok synonym: "propionyl-CoA succinate CoA-transferase activity" EXACT [] synonym: "propionyl-CoA:succinate CoA transferase activity" EXACT [] xref: EC:2.8.3.- xref: GO:0043821 xref: MetaCyc:RXN0-268 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0005989 name: ribonuclease M5 activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor." [EC:3.1.26.8, IMG:02522] subset: gosubset_prok synonym: "5S ribosomal maturation nuclease activity" EXACT [EC:3.1.26.8] synonym: "5S ribosomal RNA maturation endonuclease activity" EXACT [] synonym: "RNase M5 activity" EXACT [EC:3.1.26.8] xref: EC:3.1.26.8 xref: GO:0043822 is_a: CCO:F0003449 ! endoribonuclease activity, producing 5'-phosphomonoesters [Term] id: CCO:F0005990 name: spheroidene monooxygenase activity namespace: molecular_function def: "Catalysis of the conversion of spheroidene to spheroidenone." [IMG:01761, PMID:16086104, PMID:16158287] subset: gosubset_prok xref: EC:1.14.-.- xref: GO:0043823 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0005991 name: succinylglutamate-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH + 2 H+." [EC:1.2.1.71, IMG:00484] subset: gosubset_prok synonym: "AruD" RELATED [] synonym: "AstD" RELATED [] synonym: "N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.71] synonym: "N-succinylglutamate 5-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.71] synonym: "SGSD" RELATED [] synonym: "succinyl glutamate-semialdehyde dehydrogenase activity" EXACT [] synonym: "succinylglutamic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.71] xref: EC:1.2.1.71 xref: GO:0043824 xref: MetaCyc:SUCCGLUALDDEHYD-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0005992 name: succinylornithine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: N2-succinyl-L-ornithine + 2-oxoglutarate = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate." [EC:2.6.1.81, IMG:00483] subset: gosubset_prok synonym: "2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity" EXACT [EC:2.6.1.81] synonym: "AstC" RELATED [] synonym: "N(2)-succinylornithine 5-aminotransferase activity" EXACT [EC:2.6.1.81] synonym: "N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity" EXACT [] synonym: "N2-succinylornithine 5-aminotransferase activity" EXACT [] synonym: "SOAT" RELATED [] synonym: "succinyl ornithine transaminase activity" EXACT [] synonym: "succinyl-ornithine transaminase activity" EXACT [EC:2.6.1.81] synonym: "succinylornithine aminotransferase activity" BROAD [EC:2.6.1.81] xref: EC:2.6.1.81 xref: GO:0043825 xref: MetaCyc:SUCCORNTRANSAM-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0005993 name: sulfur oxygenase reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5 S0 + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide." [IMG:00713, MetaCyc:RXN-8226, PMID:1522063] subset: gosubset_prok synonym: "SOR" RELATED [] synonym: "sulphur oxygenase reductase activity" EXACT [] xref: EC:1.-.-.- xref: GO:0043826 xref: MetaCyc:RXN-8226 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0005994 name: tRNA (adenine-57, 58-N(1)-) methyltransferase activity namespace: molecular_function def: "Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA." [IMG:00706, PMID:14739239] subset: gosubset_prok synonym: "TrmI" RELATED [] synonym: "tRNA (adenine-57, 58 N1-) methyltransferase activity" EXACT [] synonym: "tRNA (adenine-57, 58-N1-) methyltransferase activity" EXACT [] synonym: "tRNA (m1A) MTase" BROAD [] xref: EC:2.1.1.- xref: GO:0043827 is_a: CCO:F0003151 ! tRNA (adenine-N1-)-methyltransferase activity [Term] id: CCO:F0005995 name: tRNA 2-selenouridine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA)." [IMG:02609, MetaCyc:RXN0-2281, UniProt:Q8Z8R4] subset: gosubset_prok synonym: "B0503" RELATED [] synonym: "SelU" RELATED [] synonym: "YbbB" RELATED [] xref: EC:2.9.1.- xref: GO:0043828 xref: MetaCyc:RXN0-2281 is_a: CCO:F0003358 ! selenotransferase activity [Term] id: CCO:F0005996 name: tRNA-specific adenosine-37 deaminase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule." [IMG:00703, UniProt:P53065] subset: gosubset_prok synonym: "TAD1" RELATED [] synonym: "tRNA(Ala)-A37 deaminase activity" EXACT [] synonym: "tRNA-specific adenosine deaminase 1" EXACT [] xref: EC:3.5.4.- xref: GO:0043829 is_a: CCO:F0001794 ! tRNA-specific adenosine deaminase activity [Term] id: CCO:F0005997 name: thiol-driven fumarate reductase activity namespace: molecular_function def: "Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide." [IMG:01366, PMID:2509466] subset: gosubset_prok xref: EC:1.3.99.- xref: GO:0043830 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0005998 name: thiosulfate dehydrogenase (quinone) activity namespace: molecular_function def: "Catalysis of the reaction: 2 thiosulfate + 2 6-decylubiquinone = tetrathionate + 2 6-decylubiquinol." [EC:1.8.5.2, IMG:00714, MetaCyc:1.8.5.2-RXN] subset: gosubset_prok synonym: "DoxA" RELATED [] synonym: "DoxD" RELATED [] synonym: "thiosulfate oxidoreductase, tetrathionate-forming activity" EXACT [EC:1.8.5.2] synonym: "thiosulfate:6-decylubiquinone oxidoreductase activity" EXACT [EC:1.8.5.2] synonym: "thiosulfate:quinone oxidoreductase activity" EXACT [EC:1.8.5.2] synonym: "thiosulphate dehydrogenase (quinone) activity" EXACT [] synonym: "thiosulphate:quinone oxidoreductase activity" EXACT [] synonym: "TQO" RELATED [] xref: EC:1.8.5.2 xref: GO:0043831 xref: MetaCyc:1.8.5.2-RXN is_a: CCO:F0003265 ! oxidoreductase activity, acting on sulfur group of donors, quinone or similar compound as acceptor [Term] id: CCO:F0005999 name: trans-2, cis-3 decenoyl-ACP isomerase activity namespace: molecular_function def: "Catalysis of the isomerization of trans-2-decenoyl-ACP to cis-3-decenoyl-ACP." [IMG:02508, PMID:12237320] subset: gosubset_prok synonym: "trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity" EXACT [] xref: EC:5.3.3.- xref: GO:0043832 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0006000 name: methylamine-specific methylcobalamin:coenzyme M methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M." [IMG:01318, MetaCyc:RXN-8099, UniProt:P58984] comment: This function is the second step in the pathway of methanogenesis from monomethylamine, dimethylamine and trimethylamine. subset: gosubset_prok synonym: "dimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity" NARROW [] synonym: "methylamine-specific methylcobalamin:CoM methyltransferase activity" EXACT [] synonym: "methylcobamide:coenzyme M methyltransferase activity" EXACT [] synonym: "methylcobamide:CoM methyltransferase activity" EXACT [] synonym: "methylcobamide:CoM methyltransferase II isozyme A" RELATED [] synonym: "monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity" NARROW [] synonym: "MT2" BROAD [] synonym: "MT2-A" RELATED [] synonym: "MtbA" RELATED [] synonym: "trimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity" NARROW [] xref: EC:2.1.1.- xref: GO:0043833 xref: MetaCyc:RXN-8099 xref: MetaCyc:RXN-8101 xref: MetaCyc:RXN-8103 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0006001 name: trimethylamine methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine." [IMG:01323, MetaCyc:RXN-8102, UniProt:Q8TTA9] comment: This function is the first step in the pathway of methanogenesis from trimethylamine. subset: gosubset_prok synonym: "MT1" BROAD [] synonym: "mttB1" RELATED [] synonym: "TMA methyltransferase 1" EXACT [] synonym: "trimethylamine:corrinoid methyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0043834 xref: MetaCyc:RXN-8102 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0006002 name: uracil/thymine dehydrogenase activity namespace: molecular_function def: "Catalyzes the reactions: (1) uracil + H2O + acceptor = barbiturate + reduced acceptor (2) thymine + H2O + acceptor = 5-methylbarbiturate + reduced acceptor." [EC:1.17.99.4, IMG:01821] subset: gosubset_prok synonym: "uracil oxidase activity" RELATED [EC:1.17.99.4] synonym: "uracil-thymine oxidase activity" EXACT [EC:1.17.99.4] synonym: "uracil:acceptor oxidoreductase activity" EXACT [] xref: EC:1.17.99.4 xref: GO:0043835 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0006003 name: xanthine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate." [IMG:01834, MetaCyc:R127-RXN] subset: gosubset_prok synonym: "xanthinase activity" EXACT [] xref: EC:3.5.2.- xref: GO:0043836 xref: MetaCyc:R127-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0006004 name: valine dehydrogenase (NAD) activity namespace: molecular_function def: "Catalysis of the reaction: L-valine + H(2)O + NAD(+) = 3-methyl-2-oxobutanoate + NH(3) + NADH." [IMG:00766, UniProt:O69056] subset: gosubset_prok synonym: "ValDH" RELATED [] xref: EC:1.4.1.- xref: GO:0043837 is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006005 name: phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity namespace: molecular_function def: "Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol." [IMG:00182, PMID:15795227] comment: Note that Kdo is an abbreviation for 3-deoxy-D-manno-oct-2-ulosonic acid. subset: gosubset_prok synonym: "EptB" RELATED [] synonym: "phosphoethanolamine transferase" BROAD [] xref: GO:0043838 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006006 name: lipid A phosphate methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate moiety of lipid A." [IMG:02094, PMID:15994324, UniProt:Q4FAC7] subset: gosubset_prok synonym: "lipid A 1-phosphomethyltransferase activity" EXACT [] synonym: "lipid A methyltransferase" BROAD [] synonym: "lipid A phosphomethyltransferase activity" EXACT [] synonym: "LmtA" RELATED [] xref: GO:0043839 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0006007 name: branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine." [IMG:01684, PMID:12670965] subset: gosubset_prok synonym: "BCAT" RELATED [] synonym: "branched chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity" EXACT [] synonym: "branched-chain amino acid aminotransferase" BROAD [] synonym: "branched-chain-amino-acid:2-keto-4-methylthiobutyrate aminotransferase activity" EXACT [] xref: EC:2.6.1.- xref: GO:0043840 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006009 name: Kdo transferase activity namespace: molecular_function def: "Catalysis of the reactions: (1) (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP (2) lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP." [IMG:00549, PMID:1577828, PMID:2033061, PMID:9195966] subset: gosubset_prok synonym: "3-deoxy-D-manno-octulosonic-acid transferase activity" EXACT [] synonym: "kdtA" RELATED [] synonym: "WaaA" RELATED [] xref: EC:2.-.-.- xref: GO:0043842 xref: MetaCyc:KDOTRANS-RXN xref: MetaCyc:KDOTRANS2-RXN is_a: CCO:F0003316 ! transferase activity [Term] id: CCO:F0006010 name: ADP-specific glucokinase activity namespace: molecular_function def: "Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate." [EC:2.7.1.147, IMG:01468] subset: gosubset_prok synonym: "ADP-dependent glucokinase activity" EXACT [EC:2.7.1.147] synonym: "ADP:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.147] xref: EC:2.7.1.147 xref: GO:0043843 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006011 name: ADP-specific phosphofructokinase activity namespace: molecular_function def: "Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate." [EC:2.7.1.146, IMG:01469] subset: gosubset_prok synonym: "ADP-6-phosphofructokinase activity" EXACT [EC:2.7.1.146] synonym: "ADP-dependent phosphofructokinase activity" EXACT [EC:2.7.1.146] synonym: "ADP-Pfk activity" EXACT [EC:2.7.1.146] synonym: "ADP:D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.146] xref: EC:2.7.1.146 xref: GO:0043844 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006012 name: excinuclease cho activity namespace: molecular_function def: "Catalyzes the incision of the DNA at the 3' side of a lesion." [IMG:00499, UniProt:P59439] comment: Note that this function occurs as part of nucleotide excision repair (NER). subset: gosubset_prok synonym: "cho" RELATED [] synonym: "endonuclease cho" EXACT [] synonym: "uvrc homolog protein" RELATED [] xref: GO:0043848 is_a: CCO:F0003448 ! site-specific endodeoxyribonuclease activity, specific for altered base [Term] id: CCO:F0006013 name: Ras palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins." [IMG:00473, UniProt:Q4I2M7] subset: gosubset_prok synonym: "DHHC cysteine-rich domain-containing protein ERF2" RELATED [] synonym: "ERF2" RELATED [] synonym: "palmitoyltransferase ERF2" RELATED [] synonym: "Ras protein acyltransferase activity" EXACT [] xref: EC:2.3.1.- xref: GO:0043849 is_a: CCO:F0003132 ! palmitoyltransferase activity [Term] id: CCO:F0006014 name: methanol-specific methylcobalamin:coenzyme M methyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of the methyl group from the methylated corrinoid cofactor of a methanol corrinoid protein to coenzyme M." [IMG:01315, MetaCyc:RXN-8096] comment: This function is the second step in the pathway of methanogenesis from methanol. subset: gosubset_prok synonym: "methanol-specific methylcobalamin: coenzyme M methyltransferase activity" EXACT [] synonym: "methanol-specific methylcobalamin:CoM methyltransferase activity" EXACT [] synonym: "methyltransferase 2" BROAD [] synonym: "MT2" BROAD [] synonym: "MtaA" RELATED [] synonym: "MtaC protein: coenzyme M methyltransferase activity" EXACT [] synonym: "MtaC protein:coenzyme M methyltransferase activity" EXACT [] xref: EC:2.1.1.- xref: GO:0043851 xref: MetaCyc:RXN-8096 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0006015 name: monomethylamine methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + ammonia." [IMG:01319, MetaCyc:RXN-8098] comment: This function is the first step in the pathway of methanogenesis from monomethylamine. subset: gosubset_prok synonym: "MMAMT" RELATED [] synonym: "monomethylamine:corrinoid methyltransferase activity" EXACT [] synonym: "MtmB" RELATED [] xref: EC:2.1.1.- xref: GO:0043852 xref: MetaCyc:RXN-8098 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0006016 name: cyclic nucleotide-gated mechanosensitive ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts." [GOC:jl, IMG:02416] subset: gosubset_prok synonym: "cyclic nucleotide gated mechanosensitive ion channel activity" EXACT [] synonym: "cyclic nucleotide regulated mechanosensitive ion channel" EXACT [] synonym: "cyclic nucleotide-regulated mechanosensitive ion channel" EXACT [] synonym: "cyclic nucleotide-regulated small mechanosensitive ion channel" RELATED [] synonym: "MscS" RELATED [] synonym: "small conductance mechanosensitive ion channel" EXACT [] xref: GO:0043854 is_a: CCO:F0001855 ! mechanically-gated ion channel activity is_a: CCO:F0006017 ! cyclic nucleotide-gated ion channel activity [Term] id: CCO:F0006017 name: cyclic nucleotide-gated ion channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts." [GOC:jl] subset: gosubset_prok synonym: "cyclic nucleotide activated ion channel activity" EXACT [] synonym: "cyclic nucleotide gated ion channel activity" EXACT [] synonym: "cyclic nucleotide-activated ion channel activity" EXACT [] xref: GO:0043855 is_a: CCO:F0002733 ! ligand-gated ion channel activity [Term] id: CCO:F0006018 name: anti-sigma factor antagonist activity namespace: molecular_function def: "The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity." [GOC:jl, PMID:15576799] subset: gosubset_prok synonym: "anti-anti-sigma factor activity" EXACT [] xref: GO:0043856 is_a: CCO:F0004454 ! transcription regulator activity [Term] id: CCO:F0006019 name: N-acetylornithine carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: carbamoyl phosphate + N2-acetyl-L-ornithine = phosphate + N-acetyl-L-citrulline." [EC:2.1.3.9] subset: gosubset_prok synonym: "acetylornithine transcarbamylase activity" EXACT [] synonym: "AOTC" RELATED [] synonym: "carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.9] synonym: "carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase activity" EXACT [EC:2.1.3.9] synonym: "N-acetylornithine transcarbamylase activity" EXACT [] xref: EC:2.1.3.9 xref: GO:0043857 is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0006020 name: arginine:ornithine antiporter activity namespace: molecular_function def: "Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out)." [GOC:jl, PMID:17110979] subset: gosubset_prok synonym: "ArcD" RELATED [] synonym: "arginine-ornithine antiporter activity" EXACT [] synonym: "arginine/ornithine antiporter" EXACT [] xref: GO:0043858 is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0006021 name: cyanophycinase activity namespace: molecular_function def: "Catalysis of the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides." [PMID:10429200, UniProt:P58562] subset: gosubset_prok xref: EC:3.-.-.- xref: GO:0043859 is_a: CCO:F0001786 ! serine-type peptidase activity [Term] id: CCO:F0006022 name: cyanophycin synthetase activity namespace: molecular_function def: "Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer)." [GOC:jl, UniProt:P58572] subset: gosubset_prok synonym: "cphA" RELATED [] xref: EC:6.-.-.- xref: GO:0043860 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0006023 name: agmatine:putrescine antiporter activity namespace: molecular_function def: "Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out)." [GOC:jl, PMID:17028272] subset: gosubset_prok synonym: "agmatine-putrescine antiporter activity" EXACT [] synonym: "agmatine/putrescine antiporter" EXACT [] xref: GO:0043861 is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0006024 name: arginine:agmatine antiporter activity namespace: molecular_function def: "Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out)." [GOC:jl, PMID:17099215] subset: gosubset_prok synonym: "AdiC" RELATED [] synonym: "arginine-agmatine antiporter activity" EXACT [] synonym: "arginine-agmatine exchange transporter" EXACT [] synonym: "arginine/agmatine antiporter activity" EXACT [] xref: GO:0043862 is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0006025 name: 4-hydroxy-2-ketopimelate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate." [MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN, UniProt:Q46983] subset: gosubset_prok synonym: "2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity" EXACT [] synonym: "HHED aldolase activity" EXACT [] synonym: "HpaI" RELATED [] synonym: "HpcH" RELATED [] xref: EC:4.1.2.- xref: GO:0043863 xref: MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006026 name: indoleacetamide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: indole-3-acetamide (IAM) + H2O = indole-3-acetate (IAA) + NH3." [GOC:jl, MetaCyc:RXNN-404, UniProt:Q04557] subset: gosubset_prok synonym: "IaaH" RELATED [] synonym: "IAH" EXACT [] synonym: "indole acetamide hydrolase activity" EXACT [] synonym: "indole-3-acetamide hydrolase activity" EXACT [] synonym: "Tms2" RELATED [] xref: EC:3.5.1.- xref: GO:0043864 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006027 name: methionine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of methionine from one side of a membrane to the other." [GOC:jl] subset: gosubset_prok xref: GO:0043865 is_a: CCO:F0000019 ! sulfur amino acid transmembrane transporter activity [Term] id: CCO:F0006028 name: adenylyl-sulfate reductase (thioredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin." [EC:1.8.4.10] subset: gosubset_prok synonym: "AMP, sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [] synonym: "AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)" EXACT [EC:1.8.4.10] synonym: "thioredoxin-dependent 5'-adenylylsulfate reductase activity" EXACT [] xref: EC:1.8.4.10 xref: GO:0043866 is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0006029 name: 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine." [PMID:16407303, UniProt:Q9YAC2] subset: gosubset_prok synonym: "archaeal tRNA-guanine transglycosylase activity" EXACT [] synonym: "archaeosine tRNA-ribosyltransferase activity" EXACT [] synonym: "TgtA" RELATED [] xref: EC:2.4.2.- xref: GO:0043867 is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0006030 name: N-acetylaminoadipate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + N-acetyl-L-aminoadipate = ADP + N-acetyl-L-aminoadipate 5-phosphate." [PMID:10613839, UniProt:Q9V1I5] subset: gosubset_prok synonym: "acetylaminoadipate kinase activity" EXACT [] synonym: "LysZ" RELATED [] synonym: "N-acetyl-L-aminoadipate 5-phosphotransferase activity" EXACT [] xref: EC:2.7.2.- xref: GO:0043868 xref: MetaCyc:RXN-5182 is_a: CCO:F0003114 ! kinase activity [Term] id: CCO:F0006031 name: alpha-aminoadipate acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A." [MetaCyc:RXN-5181, PMID:10613839, PMID:12925802] subset: gosubset_prok synonym: "lysine biosynthesis protein" RELATED [] synonym: "LysX" RELATED [] synonym: "RimK" RELATED [] xref: GO:0043869 xref: MetaCyc:RXN-5181 is_a: CCO:F0003130 ! acetyltransferase activity [Term] id: CCO:F0006032 name: N-acetyl-gamma-aminoadipyl-phosphate reductase activity namespace: molecular_function def: "Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP(+) + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH." [MetaCyc:RXN-5183, UniProt:Q9ZND6] comment: This function is part of the prokaryotic alpha-aminoadipate lysine biosynthesis pathway. subset: gosubset_prok synonym: "AGPR" RELATED [] synonym: "ArgC" RELATED [] synonym: "LysY" RELATED [] synonym: "N-acetyl-alpha-glutamyl-phosphate reductase activity" EXACT [] synonym: "N-acetyl-aminoadipate semialdehyde dehydrogenase activity" EXACT [] synonym: "NAGSA dehydrogenase activity" BROAD [] xref: EC:1.2.1.- xref: GO:0043870 xref: MetaCyc:RXN-5183 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006033 name: delta1-piperideine-6-carboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-pipecolate = delta1-piperideine-6-carboxylate + 2 H+." [MetaCyc:RXN-8161, PMID:16237033] comment: This function is part of the pipecolate pathway of lysine catabolism. subset: gosubset_prok synonym: "AmaB" RELATED [] synonym: "delta 1-piperideine-6-carboxylate dehydrogenase activity" EXACT [] synonym: "delta-1-piperideine-6-carboxylate dehydrogenase activity" EXACT [] synonym: "PIPOX" RELATED [] xref: GO:0043871 xref: MetaCyc:RXN-8161 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006034 name: lysine:cadaverine antiporter activity namespace: molecular_function def: "Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out)." [GOC:jl, PMID:10986235, UniProt:P0AAF0] subset: gosubset_prok synonym: "CadB" RELATED [] synonym: "lysine-cadaverine antiporter activity" EXACT [] synonym: "lysine/cadaverine antiporter activity" EXACT [] xref: GO:0043872 is_a: CCO:F0002749 ! solute:solute antiporter activity [Term] id: CCO:F0006035 name: pyruvate-flavodoxin oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin." [PMID:6352705, UniProt:Q3M8N0] subset: gosubset_prok synonym: "NifJ" RELATED [] synonym: "pyruvate:flavodoxin oxidoreductase activity" EXACT [] xref: EC:1.2.7.- xref: GO:0043873 xref: MetaCyc:PYFLAVOXRE-RXN is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0006036 name: acireductone synthase activity namespace: molecular_function def: "Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate." [EC:3.1.3.77] comment: This function is involved in the process of methionine salvage. subset: gosubset_prok synonym: "5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing)" EXACT [EC:3.1.3.77] synonym: "E-1" RELATED [] synonym: "E-1 enolase-phosphatase" BROAD [] xref: EC:3.1.3.77 xref: GO:0043874 xref: MetaCyc:3.1.3.77-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006037 name: 2-ketobutyrate formate-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate." [MetaCyc:KETOBUTFORMLY-RXN, PMID:9484901] comment: This function is part of an anaerobic pathway for the catabolism of L-threonine. subset: gosubset_prok synonym: "keto-acid formate acetyltransferase" BROAD [] synonym: "KFL" EXACT [] synonym: "TdcE" RELATED [] xref: EC:2.3.1- xref: GO:0043875 xref: MetaCyc:KETOBUTFORMLY-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006038 name: D-threonine aldolase activity namespace: molecular_function def: "Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde." [PMID:9642221, UniProt:A2SCK2] subset: gosubset_prok synonym: "D-allo-TA" EXACT [] synonym: "D-allo-threonine aldolase activity" EXACT [] synonym: "D-TA" EXACT [] synonym: "DtaAS" RELATED [] synonym: "low-specificity D-threonine aldolase" NARROW [] xref: EC:4.1.2.- xref: GO:0043876 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006039 name: galactosamine-6-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3." [UniProt:P42912] comment: This function is part of the pathway of N-acetyl-galactosamine and galactosamine utilization. subset: gosubset_prok synonym: "AgaI" RELATED [] synonym: "galactosamine-6-phosphate deaminase activity" EXACT [] xref: EC:5.3.1.- xref: GO:0043877 is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0006040 name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+." [PMID:9497334] subset: gosubset_prok synonym: "glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity" EXACT [] synonym: "glyceraldehyde-3-phosphate dehydrogenase (NAD) activity" EXACT [] synonym: "NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [] synonym: "non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)" EXACT [] xref: EC:1.2.1.- xref: GO:0043878 is_a: CCO:F0002279 ! glyceraldehyde-3-phosphate dehydrogenase activity [Term] id: CCO:F0006041 name: glycolate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA)." [GOC:jl, http://en.wikipedia.org/, UniProt:Q46839] subset: gosubset_prok synonym: "glcA" RELATED [] synonym: "glycolate permease" RELATED [] synonym: "glycolic acid transmembrane transporter activity" EXACT [] synonym: "hydroxyacetic acid transmembrane transporter activity" EXACT [] xref: GO:0043879 is_a: CCO:F0001967 ! organic anion transmembrane transporter activity [Term] id: CCO:F0006042 name: crotonyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reduction of crotonyl-CoA to butyryl-CoA." [IPR:010085, PMID:11162231, UniProt:A1B8U5] subset: gosubset_prok synonym: "CCR" EXACT [] synonym: "crotonyl-coenzyme A reductase activity" EXACT [] xref: GO:0043880 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006043 name: mesaconyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA." [PMID:16856935, PMID:16856937] comment: This function is part of an alternate glyoxylate cycle for acetate assimilation. subset: gosubset_prok synonym: "beta-methylmalyl-CoA dehydratase activity" EXACT [] synonym: "mch" RELATED [] synonym: "mesaconyl-coenzyme A hydratase activity" EXACT [] xref: GO:0043881 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006044 name: malate:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in)." [GOC:jl, UniProt:O05256] subset: gosubset_prok synonym: "malate Na(+) symporter" EXACT [] synonym: "malate-sodium symporter activity" EXACT [] synonym: "malate/sodium cotransporter activity" EXACT [] synonym: "malate/sodium symporter activity" EXACT [] synonym: "malate:Na+ symporter activity" EXACT [] synonym: "malate:sodium cotransporter activity" EXACT [] synonym: "Na(+)-malate symporter" EXACT [] synonym: "Na+:malate symporter activity" EXACT [] synonym: "sodium-dependent malate transporter" BROAD [] synonym: "sodium/malate symporter activity" EXACT [] synonym: "sodium:malate symporter activity" EXACT [] xref: GO:0043882 is_a: CCO:F0002745 ! anion:cation symporter activity [Term] id: CCO:F0006045 name: malolactic enzyme activity namespace: molecular_function def: "Catalysis of the reaction: malate + H+ = L-lactate + CO2." [MetaCyc:RXN8E-5623, PMID:3139053] comment: This function is part of the process of degradation of L-malic acid by lactic acid bacteria. subset: gosubset_prok synonym: "MleS" RELATED [] xref: EC:1.-.-.- xref: GO:0043883 xref: MetaCyc:RXN8E-5623 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006046 name: CO-methylating acetyl-CoA synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA." [EC:2.3.1.169, PMID:1748656] subset: gosubset_prok synonym: "acetyl-CoA synthase activity" BROAD [] synonym: "acetyl-CoA:corrinoid protein O-acetyltransferase activity" EXACT [] synonym: "ACS" RELATED [EC:2.3.1.169] synonym: "CO-methylating acetyl-coenzyme A synthase activity" EXACT [] xref: EC:2.3.1.169 xref: GO:0043884 xref: MetaCyc:ACETYLSYNCLTH-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006047 name: carbon-monoxide dehydrogenase (ferredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin." [EC:1.2.7.4] subset: gosubset_prok synonym: "carbon monoxide dehydrogenase (ferredoxin) activity" EXACT [] synonym: "carbon monoxide dehydrogenase activity" BROAD [] synonym: "carbon-monoxide dehydrogenase activity" BROAD [EC:1.2.7.4] synonym: "carbon-monoxide,water:ferredoxin oxidoreductase activity" EXACT [] synonym: "carbon-monoxide:(acceptor) oxidoreductase activity" EXACT [] synonym: "CO dehydrogenase activity" EXACT [] synonym: "CO-dehydrogenase (ferredoxin) activity" EXACT [] synonym: "CO-dehydrogenase activity" EXACT [] synonym: "CODH" RELATED [] xref: EC:1.2.7.4 xref: GO:0043885 xref: MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0006048 name: structural constituent of carboxysome namespace: molecular_function def: "The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in the Cyanobacteria consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide." [GOC:jl] subset: gosubset_prok xref: GO:0043886 is_a: CCO:F0001484 ! structural molecule activity [Term] id: CCO:F0006049 name: melibiose:sodium symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in)." [PMID:1970646, UniProt:P02921] subset: gosubset_prok synonym: "MelB" RELATED [] synonym: "melibiose carrier protein" RELATED [] synonym: "melibiose permease" BROAD [] synonym: "melibiose-Na+ symporter activity" EXACT [] synonym: "melibiose-sodium symporter activity" EXACT [] synonym: "melibiose/Na+ symporter activity" EXACT [] synonym: "melibiose/sodium symporter activity" EXACT [] synonym: "melibiose:Na+ symporter activity" EXACT [] synonym: "Na+ (Li+)/melibiose symporter" EXACT [] synonym: "Na+-melibiose symporter activity" EXACT [] synonym: "Na+/melibiose symporter activity" EXACT [] synonym: "Na+:melibiose symporter activity" EXACT [] synonym: "sodium-melibiose symporter activity" EXACT [] synonym: "sodium/melibiose symporter activity" EXACT [] synonym: "sodium:melibiose symporter activity" EXACT [] synonym: "thiomethylgalactoside permease II" RELATED [] xref: GO:0043887 is_a: CCO:F0002882 ! melibiose:monovalent cation symporter activity [Term] id: CCO:F0006052 name: N-acetylgalactosamine-6-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate." [EC:3.1.6.4] subset: gosubset_prok synonym: "acetylgalactosamine 6-sulfatase activity" EXACT [] synonym: "chondroitin sulfatase" BROAD [] synonym: "chondroitinase" BROAD [] synonym: "chondroitinsulfatase" BROAD [EC:3.1.6.4] synonym: "galactose-6-sulfate sulfatase activity" EXACT [] synonym: "N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity" EXACT [] synonym: "N-acetylgalactosamine 6-sulfatase activity" EXACT [] synonym: "N-acetylgalactosamine-6-sulfate sulfatase activity" EXACT [] xref: EC:3.1.6.4 xref: GO:0043890 xref: MetaCyc:3.1.6.4-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0006053 name: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity namespace: molecular_function def: "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+." [EC:1.2.1.59] subset: gosubset_prok synonym: "D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)" EXACT [] synonym: "glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)" EXACT [] synonym: "NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [EC:1.2.1.59] synonym: "triosephosphate dehydrogenase (NAD(P))" EXACT [] synonym: "triosephosphate dehydrogenase (NAD(P)+)" EXACT [EC:1.2.1.59] xref: EC:1.2.1.59 xref: GO:0043891 xref: MetaCyc:GAPDHSYNEC-RXN is_a: CCO:F0002279 ! glyceraldehyde-3-phosphate dehydrogenase activity [Term] id: CCO:F0006054 name: methylglyoxal reductase (NADPH-dependent) activity namespace: molecular_function def: "Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+." [EC:1.1.1.283] subset: gosubset_prok synonym: "Gre2" RELATED [] synonym: "lactaldehyde dehydrogenase (NADP+)" EXACT [] synonym: "lactaldehyde:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.283] xref: EC:1.1.1.283 xref: GO:0043892 xref: MetaCyc:1.1.1.283-RXN xref: MetaCyc:RXN-8636 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006055 name: acetate:cation symporter activity namespace: molecular_function def: "Catalysis of the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in)." [GOC:jl] subset: gosubset_prok synonym: "acetate permease" BROAD [] synonym: "acetate-cation symporter activity" EXACT [] synonym: "acetate/cation symporter activity" EXACT [] synonym: "ActP" RELATED [] synonym: "cation-acetate symporter activity" EXACT [] synonym: "cation/acetate symporter activity" EXACT [] synonym: "cation:acetate symporter activity" EXACT [] xref: GO:0043893 is_a: CCO:F0002743 ! solute:cation symporter activity [Term] id: CCO:F0006056 name: protein acetyltransferase activity namespace: molecular_function def: "Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate." [PMID:15236963] subset: gosubset_prok synonym: "Pat" RELATED [] synonym: "Pat enzyme" RELATED [] xref: GO:0043894 is_a: CCO:F0003130 ! acetyltransferase activity [Term] id: CCO:F0006057 name: cyclomaltodextrin glucanotransferase activity namespace: molecular_function def: "Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond." [EC:2.4.1.19] synonym: "1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing)" EXACT [] synonym: "alpha-1,4-glucan 4-glycosyltransferase, cyclizing" RELATED [] synonym: "alpha-cyclodextrin glucanotransferase" RELATED [] synonym: "alpha-cyclodextrin glycosyltransferase" RELATED [] synonym: "Bacillus macerans amylase" RELATED [] synonym: "beta-cyclodextrin glucanotransferase" RELATED [] synonym: "beta-cyclodextrin glycosyltransferase" RELATED [] synonym: "BMA" RELATED [] synonym: "CGTase" RELATED [] synonym: "cyclodextrin glucanotransferase" BROAD [] synonym: "cyclodextrin glycosyltransferase" RELATED [] synonym: "cyclomaltodextrin glucotransferase" RELATED [] synonym: "cyclomaltodextrin glycosyltransferase" RELATED [] synonym: "gamma-cyclodextrin glycosyltransferase" RELATED [] synonym: "konchizaimu" RELATED [] synonym: "neutral-cyclodextrin glycosyltransferase" RELATED [] xref: EC:2.4.1.19 xref: GO:0043895 xref: MetaCyc:2.4.1.19-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006058 name: glucan 1,6-alpha-glucosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides." [EC:3.2.1.70] subset: gosubset_prok synonym: "exo-1,6-alpha-glucosidase activity" EXACT [EC:3.2.1.70] synonym: "exo-1,6-beta-glucosidase" RELATED [] synonym: "glucan alpha-1,6-D-glucohydrolase activity" EXACT [EC:3.2.1.70] synonym: "glucan-1,6-alpha-glucosidase activity" EXACT [] synonym: "glucodextranase activity" EXACT [EC:3.2.1.70] synonym: "glucodextrinase" BROAD [] xref: EC:3.2.1.70 xref: GO:0043896 xref: MetaCyc:3.2.1.70-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006059 name: glucan 1,4-alpha-maltohydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains." [EC:3.2.1.133] subset: gosubset_prok synonym: "1,4-alpha-D-glucan alpha-maltohydrolase activity" EXACT [] synonym: "glucan-1,4-alpha-maltohydrolase activity" EXACT [] synonym: "maltogenic alpha-amylase activity" EXACT [] xref: EC:3.2.1.133 xref: GO:0043897 xref: MetaCyc:3.2.1.133-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006060 name: HDEL sequence binding namespace: molecular_function def: "Interacting selectively with a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum." [PMID:1327759] synonym: "HDEL receptor activity" NARROW [] xref: GO:0045015 is_a: CCO:F0006275 ! ER retention sequence binding [Term] id: CCO:F0006061 name: peptidyl-glutamyl peptide hydrolyzing enzyme activity namespace: molecular_function def: "Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids." [PMID:11735414] xref: GO:0045024 is_a: CCO:F0001783 ! peptidase activity [Term] id: CCO:F0006062 name: DNA end binding namespace: molecular_function def: "Interacting selectively with the ends of DNA that are exposed by the creation of double-strand breaks (DSBs)." [GOC:jl] xref: GO:0045027 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0006063 name: purinergic nucleotide receptor activity, G-protein coupled namespace: molecular_function def: "Combining with a purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity." [GOC:mah, PMID:9755289] synonym: "G protein coupled purinergic nucleotide receptor activity" EXACT [] synonym: "G-protein coupled purinergic nucleotide receptor activity" EXACT [] synonym: "G-protein-coupled purinergic nucleotide receptor activity" EXACT [] synonym: "P2Y" RELATED [] synonym: "purinergic nucleotide receptor activity, G protein coupled" EXACT [] xref: GO:0045028 is_a: CCO:F0000163 ! nucleotide receptor activity, G-protein coupled is_a: CCO:F0000165 ! purinergic nucleotide receptor activity [Term] id: CCO:F0006064 name: UDP-activated nucleotide receptor activity namespace: molecular_function xref: GO:0045029 is_a: CCO:F0002552 ! uridine nucleotide receptor activity [Term] id: CCO:F0006065 name: UTP-activated nucleotide receptor activity namespace: molecular_function xref: GO:0045030 is_a: CCO:F0002552 ! uridine nucleotide receptor activity [Term] id: CCO:F0006066 name: ATP-activated nucleotide receptor activity namespace: molecular_function xref: GO:0045031 is_a: CCO:F0000164 ! adenosine receptor activity, G-protein coupled [Term] id: CCO:F0006067 name: ADP-activated nucleotide receptor activity namespace: molecular_function xref: GO:0045032 is_a: CCO:F0000164 ! adenosine receptor activity, G-protein coupled [Term] id: CCO:F0006068 name: interleukin-18 alpha subunit binding namespace: molecular_function def: "Interacting selectively with the alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells." [PMID:10653850, UniProtKB:Q14116] synonym: "IL-18Ra binding" EXACT [] xref: GO:0045093 is_a: CCO:F0005596 ! interleukin-18 binding [Term] id: CCO:F0006069 name: interleukin-18 beta subunit binding namespace: molecular_function def: "Interacting selectively with the beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a." [PMID:10653850, UniProtKB:Q14116] synonym: "IL-18Rb binding" EXACT [] xref: GO:0045094 is_a: CCO:F0005596 ! interleukin-18 binding [Term] id: CCO:F0006070 name: azole transporter activity namespace: molecular_function def: "Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, into, out of, within or between cells." [GOC:go_curators, http://cancerweb.ncl.ac.uk/] xref: GO:0045118 is_a: CCO:F0002706 ! drug transporter activity [Term] id: CCO:F0006071 name: azole:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances." [GOC:ai, http://cancerweb.ncl.ac.uk/] synonym: "bicyclomycin/sulfathiazole:hydrogen antiporter activity" NARROW [] xref: GO:0045119 is_a: CCO:F0002753 ! drug:hydrogen antiporter activity [Term] id: CCO:F0006072 name: bioactive lipid receptor activity namespace: molecular_function xref: GO:0045125 is_a: CCO:F0001272 ! G-protein coupled receptor activity [Term] id: CCO:F0006073 name: N-acetylglucosamine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate." [EC:2.7.1.59] subset: gosubset_prok synonym: "2-acetylamino-2-deoxy-D-glucose kinase activity" EXACT [EC:2.7.1.59] synonym: "acetylaminodeoxyglucokinase activity" EXACT [EC:2.7.1.59] synonym: "acetylglucosamine kinase (phosphorylating)" EXACT [EC:2.7.1.59] synonym: "ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.59] synonym: "ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity" EXACT [EC:2.7.1.59] synonym: "GlcNAc kinase activity" EXACT [EC:2.7.1.59] xref: EC:2.7.1.59 xref: GO:0045127 xref: MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN is_a: CCO:F0004123 ! carbohydrate kinase activity [Term] id: CCO:F0006074 name: NAD-independent histone deacetylase activity namespace: molecular_function def: "Catalysis of the removal of acetyl groups from histones, independently of NAD." [GOC:ai] synonym: "AcuC" RELATED [] xref: GO:0045129 is_a: CCO:F0000816 ! histone deacetylase activity [Term] id: CCO:F0006075 name: keratan sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate." [EC:2.8.2.21] synonym: "3'-phosphoadenylyl keratan sulfotransferase activity" EXACT [EC:2.8.2.21] synonym: "3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase activity" EXACT [EC:2.8.2.21] synonym: "3'-phosphoadenylylsulfate:keratan sulfotransferase activity" EXACT [EC:2.8.2.21] synonym: "keratan sulfate Gal-6-sulfotransferase activity" EXACT [] synonym: "keratan sulfate sulfotransferase activity" EXACT [EC:2.8.2.21] synonym: "keratan sulphotransferase activity" EXACT [] xref: EC:2.8.2.21 xref: GO:0045130 xref: MetaCyc:KERATAN-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006076 name: pre-mRNA branch point binding namespace: molecular_function def: "Interacting selectively with a pre-mRNA branch point sequence, located upstream of the 3' splice site." [PMID:11691992, PMID:9722632] xref: GO:0045131 is_a: CCO:F0000313 ! mRNA binding is_a: CCO:F0004638 ! RNA splicing factor activity, transesterification mechanism [Term] id: CCO:F0006077 name: 2,3-dihydroxybenzoate 3,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 3-carboxy-2-hydroxymuconate semialdehyde." [EC:1.13.11.14] synonym: "2,3-dihydroxybenzoate 1,2-dioxygenase activity" EXACT [EC:1.13.11.14] synonym: "2,3-dihydroxybenzoate oxygenase activity" EXACT [EC:1.13.11.14] synonym: "2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.14] synonym: "2,3-dihydroxybenzoic oxygenase activity" EXACT [EC:1.13.11.14] synonym: "o-pyrocatechuate oxygenase activity" EXACT [EC:1.13.11.14] xref: EC:1.13.11.14 xref: GO:0045133 xref: MetaCyc:1.13.11.14-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006078 name: uridine-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: UDP + H2O = UMP + phosphate." [EC:3.6.1.6] synonym: "UDPase activity" EXACT [EC:3.6.1.6] synonym: "uridine 5'-diphosphatase activity" EXACT [EC:3.6.1.6] synonym: "uridine diphosphatase activity" EXACT [EC:3.6.1.6] xref: GO:0045134 is_a: CCO:F0003573 ! nucleoside-diphosphatase activity [Term] id: CCO:F0006079 name: poly(beta-D-mannuronate) lyase activity namespace: molecular_function def: "Catalysis of the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends." [EC:4.2.2.3] subset: gosubset_prok synonym: "alginase activity" EXACT [EC:4.2.2.3] synonym: "alginase I" RELATED [EC:4.2.2.3] synonym: "alginate lyase activity" EXACT [EC:4.2.2.3] synonym: "alginate lyase I activity" NARROW [EC:4.2.2.3] synonym: "poly(beta-D-1,4-mannuronide) lyase activity" EXACT [EC:4.2.2.3] synonym: "poly(mana) alginate lyase activity" NARROW [EC:4.2.2.3] xref: EC:4.2.2.3 xref: GO:0045135 xref: MetaCyc:4.2.2.3-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006080 name: inositol phosphoceramide synthase activity namespace: molecular_function def: "Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide." [MetaCyc:RXN3O-581, PMID:9405490, PMID:9614099] synonym: "IPC synthase activity" EXACT [] xref: EC:2.4.1.- xref: GO:0045140 xref: MetaCyc:RXN3O-581 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006081 name: triplex DNA binding namespace: molecular_function def: "Interacting selectively with a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination." [PMID:10681538] xref: GO:0045142 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0006082 name: single-stranded DNA specific 5'-3' exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a single-stranded DNA molecule." [GOC:ai] xref: GO:0045145 is_a: CCO:F0001819 ! single-stranded DNA specific exodeoxyribonuclease activity is_a: CCO:F0005595 ! 5'-3' exodeoxyribonuclease activity [Term] id: CCO:F0006083 name: tripeptide aminopeptidase activity namespace: molecular_function def: "Catalysis of the release of the N-terminal residue from a tripeptide." [EC:3.4.11.4] subset: gosubset_prok synonym: "alanine-phenylalanine-proline arylamidase activity" EXACT [EC:3.4.11.4] synonym: "aminoexotripeptidase activity" EXACT [EC:3.4.11.4] synonym: "aminotripeptidase activity" EXACT [] synonym: "imidoendopeptidase activity" EXACT [EC:3.4.11.4] synonym: "lymphopeptidase activity" EXACT [EC:3.4.11.4] synonym: "peptidase B" RELATED [EC:3.4.11.4] synonym: "peptidase T" EXACT [] synonym: "tripeptidase activity" EXACT [] xref: EC:3.4.11.4 xref: GO:0045148 xref: MetaCyc:3.4.11.4-RXN is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0006084 name: antisigma factor binding namespace: molecular_function def: "Interacting selectively with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator." [GOC:mlg] subset: gosubset_prok synonym: "antisigma factor antagonist activity" NARROW [] xref: GO:0045152 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006085 name: electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity namespace: molecular_function def: "Enables the directed movement of electrons within the CoQH2-cytochrome c reductase complex." [GOC:ai, ISBN:0716731363] synonym: "cytochrome" RELATED [] synonym: "cytochrome b562" NARROW [] synonym: "cytochrome b566" NARROW [] synonym: "cytochrome c1" NARROW [] synonym: "soluble cytochrome b562" RELATED [] xref: GO:0045153 xref: Reactome:19911 is_a: CCO:F0002378 ! electron carrier activity [Term] id: CCO:F0006086 name: electron transporter, transferring electrons within cytochrome c oxidase complex activity namespace: molecular_function def: "Enables the directed movement of electrons within the cytochrome c oxidase complex." [GOC:ai, ISBN:0716731363] synonym: "cytochrome" RELATED [] synonym: "cytochrome a" NARROW [] synonym: "cytochrome a3/copper complex" NARROW [] xref: GO:0045154 is_a: CCO:F0002378 ! electron carrier activity [Term] id: CCO:F0006087 name: electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity namespace: molecular_function def: "Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex." [GOC:ai, ISBN:0716731363] subset: gosubset_prok synonym: "cytochrome" RELATED [] synonym: "cytochrome c" NARROW [] xref: GO:0045155 is_a: CCO:F0002378 ! electron carrier activity [Term] id: CCO:F0006088 name: electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity namespace: molecular_function def: "Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis." [GOC:ai, ISBN:0716731363] subset: gosubset_prok synonym: "cytochrome" RELATED [] synonym: "cytochrome bc1 complex" NARROW [] xref: GO:0045156 is_a: CCO:F0002378 ! electron carrier activity [Term] id: CCO:F0006089 name: electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity namespace: molecular_function def: "Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis." [GOC:ai, ISBN:0716731363] synonym: "cytochrome" RELATED [] xref: GO:0045157 is_a: CCO:F0002378 ! electron carrier activity [Term] id: CCO:F0006090 name: electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity namespace: molecular_function def: "Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II." [GOC:ai, ISBN:0716731363] subset: gosubset_prok synonym: "cytochrome" RELATED [] synonym: "cytochrome b/b6" RELATED [] synonym: "cytochrome b6" NARROW [] synonym: "cytochrome f" NARROW [] xref: GO:0045158 is_a: CCO:F0002378 ! electron carrier activity [Term] id: CCO:F0006091 name: myosin II binding namespace: molecular_function def: "Interacting selectively with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin." [GOC:mah, http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html] xref: GO:0045159 is_a: CCO:F0003516 ! myosin binding [Term] id: CCO:F0006092 name: glutathione dehydrogenase (ascorbate) activity namespace: molecular_function def: "Catalysis of the reaction: 2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate." [EC:1.8.5.1] synonym: "dehydroascorbate reductase activity" EXACT [] synonym: "dehydroascorbic acid reductase activity" EXACT [EC:1.8.5.1] synonym: "dehydroascorbic reductase activity" EXACT [EC:1.8.5.1] synonym: "DHA reductase activity" EXACT [EC:1.8.5.1] synonym: "GDOR" RELATED [EC:1.8.5.1] synonym: "glutathione dehydroascorbate reductase activity" EXACT [EC:1.8.5.1] synonym: "glutathione:dehydroascorbate oxidoreductase activity" EXACT [EC:1.8.5.1] synonym: "glutathione:dehydroascorbic acid oxidoreductase activity" EXACT [EC:1.8.5.1] xref: EC:1.8.5.1 xref: GO:0045174 xref: MetaCyc:1.8.5.1-RXN is_a: CCO:F0002535 ! glutathione disulfide oxidoreductase activity is_a: CCO:F0003069 ! antioxidant activity is_a: CCO:F0003265 ! oxidoreductase activity, acting on sulfur group of donors, quinone or similar compound as acceptor [Term] id: CCO:F0006093 name: glutamate synthase activity, NADH or NADPH as acceptor namespace: molecular_function def: "Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+." [EC:1.4.1.13, EC:1.4.1.14] subset: gosubset_prok xref: EC:1.4.1.- xref: GO:0045181 is_a: CCO:F0003025 ! glutamate synthase activity is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006094 name: translation regulator activity namespace: molecular_function def: "Any substance involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome." [GOC:ai] subset: goslim_candida subset: goslim_generic subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "translation factor activity" EXACT [] xref: GO:0045182 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0006095 name: translation factor activity, non-nucleic acid binding namespace: molecular_function def: "Any of a group of soluble proteins involved in polypeptide synthesis at the ribosome which do not bind to nucleic acids." [GOC:ai] subset: gosubset_prok xref: GO:0045183 is_a: CCO:F0006094 ! translation regulator activity [Term] id: CCO:F0006096 name: natural killer cell receptor activity namespace: molecular_function def: "A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family." [GOC:ebc] synonym: "Ly49i" NARROW [] synonym: "NK cell receptor activity" EXACT [] xref: GO:0045233 is_a: CCO:F0001240 ! transmembrane receptor activity [Term] id: CCO:F0006097 name: CXCR chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a chemokine receptor in the CXCR family." [GOC:ceb, PMID:11910892] synonym: "alpha chemokine receptor binding" EXACT [] synonym: "alpha chemokine receptor ligand" NARROW [] synonym: "C-X-C chemokine receptor ligand" NARROW [] synonym: "CXC chemokine receptor ligand" NARROW [] xref: GO:0045236 is_a: CCO:F0005665 ! chemokine receptor binding [Term] id: CCO:F0006098 name: CXCR1 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with the CXCR1 chemokine receptor." [GOC:ceb, PMID:11910892] synonym: "CXCR1 chemokine receptor ligand" NARROW [] xref: GO:0045237 is_a: CCO:F0006097 ! CXCR chemokine receptor binding [Term] id: CCO:F0006099 name: CXCR2 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with the CXCR2 chemokine receptor." [GOC:ceb, PMID:11910892] synonym: "CXCR2 chemokine receptor ligand" NARROW [] xref: GO:0045238 is_a: CCO:F0006097 ! CXCR chemokine receptor binding [Term] id: CCO:F0006100 name: luciferin monooxygenase activity namespace: molecular_function def: "Catalysis of the oxidation of luciferin. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation." [GOC:bf] synonym: "luciferase activity" EXACT [] synonym: "luciferase monooxygenase activity" RELATED [] xref: GO:0045289 is_a: CCO:F0000894 ! monooxygenase activity [Term] id: CCO:F0006101 name: D-arabinose 1-dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+. Also acts on L-galactose, 6-deoxy- and 3,6-dideoxy-L-galactose." [EC:1.1.1.117] synonym: "D-arabinose:NAD(P)+ 1-oxidoreductase activity" EXACT [EC:1.1.1.117] xref: EC:1.1.1.117 xref: GO:0045290 xref: MetaCyc:1.1.1.117-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006102 name: alpha-catenin binding namespace: molecular_function def: "Interacting selectively with the alpha subunit of the catenin complex." [GOC:bf] xref: GO:0045294 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006103 name: gamma-catenin binding namespace: molecular_function def: "Interacting selectively with the gamma subunit of the catenin complex." [GOC:bf] xref: GO:0045295 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006104 name: cadherin binding namespace: molecular_function def: "Interacting selectively with cadherin, a type I membrane protein involved in cell adhesion." [GOC:bf] xref: GO:0045296 is_a: CCO:F0008023 ! cell adhesion molecule binding [Term] id: CCO:F0006105 name: acyl-[acyl-carrier-protein] desaturase activity namespace: molecular_function def: "Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin." [EC:1.14.19.2] comment: Note that this function was formerly EC:1.14.99.6. subset: gosubset_prok synonym: "acyl-[acyl-carrier protein] desaturase activity" EXACT [] synonym: "acyl-acyl-carrier-protein desaturase activity" EXACT [EC:1.14.19.2] synonym: "acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.19.2] synonym: "stearyl acyl carrier protein desaturase activity" EXACT [EC:1.14.19.2] synonym: "stearyl-ACP desaturase activity" EXACT [EC:1.14.19.2] xref: EC:1.14.19.2 xref: GO:0045300 xref: MetaCyc:1.14.19.2-RXN xref: MetaCyc:PWY-5147 is_a: CCO:F0003300 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Term] id: CCO:F0006106 name: tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin." [GOC:mlg, PMID:8253666] subset: gosubset_prok synonym: "2-methylthio-cis-ribozeatin hydroxylase activity" EXACT [] synonym: "tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity" EXACT [] synonym: "tRNA-(ms2io6A)-hydroxylase activity" EXACT [] xref: GO:0045301 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006107 name: choloylglycine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine." [EC:3.5.1.24] subset: gosubset_prok synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity" EXACT [EC:3.5.1.24] synonym: "bile salt hydrolase activity" EXACT [EC:3.5.1.24] synonym: "choloyltaurine hydrolase activity" EXACT [EC:3.5.1.24] synonym: "glycocholase activity" EXACT [EC:3.5.1.24] xref: EC:3.5.1.24 xref: GO:0045302 xref: MetaCyc:CHOLOYLGLYCINE-HYDROLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006108 name: diaminobutyrate-2-oxoglutarate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-2,4-diaminobutyrate + 2-oxoglutarate = L-glutamate + L-aspartic 4-semialdehyde." [EC:2.6.1.76] subset: gosubset_prok synonym: "2,4-diaminobutyrate 4-aminotransferase activity" EXACT [EC:2.6.1.76] synonym: "DAB aminotransferase activity" EXACT [EC:2.6.1.76] synonym: "DABA aminotransferase activity" EXACT [EC:2.6.1.76] synonym: "diaminibutyric acid aminotransferase activity" EXACT [EC:2.6.1.76] synonym: "diaminobutyrate transaminase activity" EXACT [EC:2.6.1.76] synonym: "diaminobutyrate--2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.76] synonym: "EctB" RELATED [EC:2.6.1.76] synonym: "L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity" EXACT [EC:2.6.1.76] synonym: "L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity" EXACT [EC:2.6.1.76] synonym: "L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity" EXACT [EC:2.6.1.76] xref: EC:2.6.1.76 xref: GO:0045303 xref: MetaCyc:2.6.1.76-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006109 name: protein phosphorylated amino acid binding namespace: molecular_function def: "Interacting selectively with a phosphorylated amino acid residue within a protein." [GOC:go_curators] synonym: "phosphoprotein amino acid binding" RELATED [] xref: GO:0045309 is_a: CCO:F0008071 ! phosphoprotein binding [Term] id: CCO:F0006110 name: unmethylated CpG binding namespace: molecular_function def: "Interacting selectively with unmethylated CpG motifs. Unmethylated CpG dinucleotides are often associated with gene promoters." [GOC:ai, PMID:10688657] xref: GO:0045322 is_a: CCO:F0005877 ! sequence-specific DNA binding [Term] id: CCO:F0006111 name: aspartyl esterase activity namespace: molecular_function def: "Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue." [GOC:mah, UniProtKB:kwdictionary] subset: gosubset_prok xref: GO:0045330 is_a: CCO:F0003360 ! hydrolase activity, acting on ester bonds [Term] id: CCO:F0006112 name: mercury ion binding namespace: molecular_function def: "Interacting selectively with mercury (Hg) ions." [GOC:go_curators] subset: gosubset_prok synonym: "mercury binding" EXACT [] xref: GO:0045340 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0006113 name: interleukin-1 Type I receptor antagonist activity namespace: molecular_function def: "Blocks the binding of interleukin-1 to interleukin-1 Type I receptors." [GOC:ebc] synonym: "IL-1ra type I" EXACT [] xref: GO:0045352 is_a: CCO:F0001454 ! interleukin-1 receptor antagonist activity [Term] id: CCO:F0006114 name: interleukin-1 Type II receptor antagonist activity namespace: molecular_function def: "Blocks the binding of interleukin-1 to interleukin-1 Type II receptors." [GOC:ebc] synonym: "IL-1ra type II" EXACT [] xref: GO:0045353 is_a: CCO:F0001454 ! interleukin-1 receptor antagonist activity [Term] id: CCO:F0006115 name: chalcone isomerase activity namespace: molecular_function def: "Catalysis of the reaction: a chalcone = a flavanone." [EC:5.5.1.6] synonym: "chalcone--flavonone isomerase activity" EXACT [EC:5.5.1.6] synonym: "chalcone-flavanone isomerase activity" EXACT [] synonym: "flavanone lyase (decyclizing)" EXACT [EC:5.5.1.6] xref: EC:5.5.1.6 xref: GO:0045430 xref: MetaCyc:CHALCONE-ISOMERASE-RXN is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0006116 name: flavonol synthase activity namespace: molecular_function def: "Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O." [EC:1.14.11.23, ISBN:0943088372, PMID:7904213] synonym: "dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.23] synonym: "flavonoid 2-oxoglutarate-dependent dioxygenase activity" EXACT [EC:1.14.11.23] synonym: "FLS activity" RELATED [EC:1.14.11.23] xref: EC:1.14.11.23 xref: GO:0045431 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006117 name: lycopene epsilon cyclase activity namespace: molecular_function def: "Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene)." [PMID:8837512] synonym: "lycopene cyclase" BROAD [] xref: GO:0045435 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0006118 name: lycopene beta cyclase activity namespace: molecular_function def: "Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively." [PMID:8837512] subset: gosubset_prok synonym: "crtL" RELATED [] synonym: "lycopene cyclase" BROAD [] xref: GO:0045436 xref: MetaCyc:RXN1F-150 is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0006119 name: uridine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: uridine + H2O = D-ribose + uracil." [EC:3.2.2.3] subset: gosubset_prok synonym: "uridine hydrolase activity" EXACT [] synonym: "uridine ribohydrolase activity" EXACT [EC:3.2.2.3] xref: EC:3.2.2.3 xref: GO:0045437 xref: MetaCyc:URIDINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0006120 name: L-cysteinyl-D-valine synthetase activity namespace: molecular_function def: "Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol." [PMID:1572368, PMID:2061333] synonym: "ACV synthetase activity" BROAD [] xref: GO:0045438 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0006121 name: isopenicillin-N epimerase activity namespace: molecular_function def: "Catalysis of the reaction: isopenicillin-N = penicillin-N." [EC:5.1.1.17, KEGG_PATHWAY:map00311] subset: gosubset_prok synonym: "isopenicillin N epimerase activity" EXACT [] synonym: "penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity" EXACT [EC:5.1.1.17] xref: EC:5.1.1.17 xref: GO:0045439 xref: MetaCyc:5.1.1.17-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0006122 name: deacetoxycephalosporin C synthetase activity namespace: molecular_function def: "Catalysis of the formation of deacetoxycephalosporin from penicillin-N." [KEGG_PATHWAY:map00311] synonym: "DAOCS" EXACT [] synonym: "expandase activity" EXACT [] xref: GO:0045441 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006123 name: deacetoxycephalosporin-C hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: deacetoxycephalosporin C + 2-oxoglutarate + O2 = deacetylcephalosporin C + succinate + CO2." [EC:1.14.11.26] synonym: "3'-methylcephem hydroxylase activity" EXACT [EC:1.14.11.26] synonym: "beta-lactam hydroxylase activity" EXACT [] synonym: "DACS" RELATED [EC:1.14.11.26] synonym: "DAOC hydroxylase activity" EXACT [EC:1.14.11.26] synonym: "deacetoxycephalosporin C hydroxylase activity" EXACT [EC:1.14.11.26] synonym: "deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.26] synonym: "deacetylcephalosporin C synthase activity" EXACT [EC:1.14.11.26] xref: EC:1.14.11.26 xref: GO:0045442 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006124 name: trichothecene 3-O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis." [PMID:10583973] xref: GO:0045462 is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006125 name: galactose oxidase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + H2O2." [EC:1.1.3.9] synonym: "beta-galactose oxidase activity" RELATED [EC:1.1.3.9] synonym: "D-galactose oxidase activity" EXACT [EC:1.1.3.9] synonym: "D-galactose:oxygen 6-oxidoreductase activity" EXACT [EC:1.1.3.9] xref: EC:1.1.3.9 xref: GO:0045480 xref: MetaCyc:GALACTOSE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0006126 name: 6-endo-hydroxycineole dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 6-endo-hydroxycineole + NAD+ = 6-oxocineole + NADH + H+." [EC:1.1.1.241] synonym: "6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity" EXACT [EC:1.1.1.241] xref: EC:1.1.1.241 xref: GO:0045481 xref: MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006127 name: trichodiene synthase activity namespace: molecular_function def: "Catalysis of the reaction: trans,trans-farnesyl diphosphate = trichodiene + diphosphate." [EC:4.2.3.6] synonym: "sesquiterpene cyclase activity" BROAD [EC:4.2.3.6] synonym: "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)" EXACT [EC:4.2.3.6] synonym: "trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity" EXACT [EC:4.2.3.6] synonym: "trichodiene synthetase activity" EXACT [EC:4.2.3.6] xref: EC:4.2.3.6 xref: GO:0045482 xref: MetaCyc:TRICHODIENE-SYNTHASE-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0006128 name: aristolochene synthase activity namespace: molecular_function def: "Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate." [EC:4.2.3.9] synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)" EXACT [EC:4.2.3.9] synonym: "5-epi-aristolochene synthase activity" EXACT [EC:4.2.3.9] synonym: "sesquiterpene cyclase activity" BROAD [EC:4.2.3.9] synonym: "trans,trans-farnesyl diphosphate aristolochene-lyase activity" EXACT [EC:4.2.3.9] synonym: "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)" EXACT [EC:4.2.3.9] xref: EC:4.2.3.9 xref: GO:0045483 xref: MetaCyc:ARISTOLOCHENE-SYNTHASE-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0006129 name: L-lysine 6-transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine + 2-oxoglutarate = 2-aminoadipate 6-semialdehyde + L-glutamate." [EC:2.6.1.36] subset: gosubset_prok synonym: "L-lysine aminotransferase activity" EXACT [EC:2.6.1.36] synonym: "L-lysine transaminase activity" EXACT [EC:2.6.1.36] synonym: "L-lysine-alpha-ketoglutarate 6-aminotransferase activity" EXACT [EC:2.6.1.36] synonym: "L-lysine-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.36] synonym: "L-lysine:2-oxoglutarate 6-aminotransferase activity" EXACT [EC:2.6.1.36] synonym: "lysine 6-aminotransferase activity" EXACT [] synonym: "lysine epsilon-aminotransferase activity" EXACT [EC:2.6.1.36] synonym: "lysine epsilon-transaminase activity" EXACT [EC:2.6.1.36] synonym: "lysine:2-ketoglutarate 6-aminotransferase activity" EXACT [EC:2.6.1.36] xref: EC:2.6.1.36 xref: GO:0045484 xref: MetaCyc:L-LYSINE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006130 name: omega-6 fatty acid desaturase activity namespace: molecular_function def: "Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain." [PMID:7846158] xref: GO:0045485 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0006131 name: naringenin 3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2." [EC:1.14.11.9] synonym: "(2S)-flavanone 3-hydroxylase activity" EXACT [EC:1.14.11.9] synonym: "flavanone 3-beta-hydroxylase activity" EXACT [EC:1.14.11.9] synonym: "flavanone 3-dioxygenase activity" EXACT [EC:1.14.11.9] synonym: "flavanone 3-hydroxylase activity" EXACT [EC:1.14.11.9] synonym: "flavanone 3beta-hydroxylase activity" EXACT [EC:1.14.11.9] synonym: "flavanone synthase I activity" EXACT [EC:1.14.11.9] synonym: "flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.9] synonym: "naringenin 3-hydroxylase activity" EXACT [EC:1.14.11.9] synonym: "naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.11.9] xref: EC:1.14.11.9 xref: GO:0045486 xref: MetaCyc:NARINGENIN-3-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006132 name: chemorepellent activity namespace: molecular_function def: "Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal." [GOC:ai] subset: goslim_pir subset: gosubset_prok synonym: "chemorepellant activity" EXACT [] xref: GO:0045499 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0006133 name: dynein binding namespace: molecular_function def: "Interacting selectively with dynein, the multisubunit protein complex that is associated with microtubules." [GOC:bf] xref: GO:0045502 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006134 name: dynein light chain binding namespace: molecular_function def: "Interacting selectively with a light chain of the dynein complex." [GOC:bf] xref: GO:0045503 is_a: CCO:F0006133 ! dynein binding [Term] id: CCO:F0006135 name: dynein heavy chain binding namespace: molecular_function def: "Interacting selectively with a heavy chain of the dynein complex." [GOC:bf] xref: GO:0045504 is_a: CCO:F0006133 ! dynein binding [Term] id: CCO:F0006136 name: dynein intermediate chain binding namespace: molecular_function def: "Interacting selectively with an intermediate chain of the dynein complex." [GOC:bf] xref: GO:0045505 is_a: CCO:F0006133 ! dynein binding [Term] id: CCO:F0006137 name: interleukin-24 receptor activity namespace: molecular_function def: "Combining with interleukin-24 to initiate a change in cell activity." [GOC:jl] synonym: "IL-24R" EXACT [] xref: GO:0045506 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0006141 ! interleukin-24 binding [Term] id: CCO:F0006138 name: interleukin-25 receptor activity namespace: molecular_function def: "Combining with interleukin-25 to initiate a change in cell activity." [GOC:jl] synonym: "IL-25R" EXACT [] xref: GO:0045507 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0006142 ! interleukin-25 binding [Term] id: CCO:F0006139 name: interleukin-26 receptor activity namespace: molecular_function def: "Combining with interleukin-26 to initiate a change in cell activity." [GOC:jl] synonym: "IL-26R" EXACT [] xref: GO:0045508 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0006143 ! interleukin-26 binding [Term] id: CCO:F0006140 name: interleukin-27 receptor activity namespace: molecular_function def: "Combining with interleukin-27 to initiate a change in cell activity." [GOC:jl] synonym: "IL-27R" EXACT [] xref: GO:0045509 is_a: CCO:F0001254 ! interleukin receptor activity is_a: CCO:F0006144 ! interleukin-27 binding [Term] id: CCO:F0006141 name: interleukin-24 binding namespace: molecular_function def: "Interacting selectively with interleukin-24." [GOC:go_curators] synonym: "IL-24 binding" EXACT [] xref: GO:0045510 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0006142 name: interleukin-25 binding namespace: molecular_function def: "Interacting selectively with interleukin-25." [GOC:go_curators] synonym: "IL-25 binding" EXACT [] xref: GO:0045511 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0006143 name: interleukin-26 binding namespace: molecular_function def: "Interacting selectively with interleukin-26." [GOC:go_curators] synonym: "IL-26 binding" EXACT [] xref: GO:0045512 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0006144 name: interleukin-27 binding namespace: molecular_function def: "Interacting selectively with interleukin-27." [GOC:go_curators] synonym: "IL-27 binding" EXACT [] xref: GO:0045513 is_a: CCO:F0004230 ! interleukin binding [Term] id: CCO:F0006145 name: interleukin-16 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-16 receptor." [GOC:go_curators] synonym: "IL-16" NARROW [] synonym: "interleukin-16 receptor ligand" NARROW [] xref: GO:0045514 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006146 name: interleukin-18 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-18 receptor." [GOC:go_curators] synonym: "IL-18" NARROW [] synonym: "interleukin-18 receptor ligand" NARROW [] xref: GO:0045515 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006147 name: interleukin-19 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-19 receptor." [GOC:go_curators] synonym: "IL-19" NARROW [] synonym: "interleukin-19 receptor ligand" NARROW [] xref: GO:0045516 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006148 name: interleukin-20 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-20 receptor." [GOC:go_curators] synonym: "IL-20" NARROW [] synonym: "interleukin-20 receptor ligand" NARROW [] xref: GO:0045517 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006149 name: interleukin-22 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-22 receptor." [GOC:go_curators] synonym: "IL-22" NARROW [] synonym: "interleukin-22 receptor ligand" NARROW [] xref: GO:0045518 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006150 name: interleukin-23 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-23 receptor." [GOC:go_curators] synonym: "IL-23" NARROW [] synonym: "interleukin-23 receptor ligand" NARROW [] xref: GO:0045519 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006151 name: interleukin-24 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-24 receptor." [GOC:go_curators] synonym: "IL-24" NARROW [] synonym: "interleukin-24 receptor ligand" NARROW [] xref: GO:0045520 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006152 name: interleukin-25 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-25 receptor." [GOC:go_curators] synonym: "IL-25" NARROW [] synonym: "interleukin-25 receptor ligand" NARROW [] xref: GO:0045521 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006153 name: interleukin-26 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-26 receptor." [GOC:go_curators] synonym: "IL-26" NARROW [] synonym: "interleukin-26 receptor ligand" NARROW [] xref: GO:0045522 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006154 name: interleukin-27 receptor binding namespace: molecular_function def: "Interacting selectively with the interleukin-27 receptor." [GOC:go_curators] synonym: "IL-27" NARROW [] synonym: "interleukin-27 receptor ligand" NARROW [] xref: GO:0045523 is_a: CCO:F0001427 ! cytokine activity [Term] id: CCO:F0006155 name: gibberellin 2-beta-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: gibberellin 1 + 2-oxoglutarate + O2 = 2-beta-hydroxygibberellin 1 + succinate + CO2." [EC:1.14.11.13] synonym: "(gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)" EXACT [EC:1.14.11.13] synonym: "gibberellin 2-beta-hydroxylase activity" EXACT [EC:1.14.11.13] synonym: "gibberellin 2-oxidase activity" EXACT [] synonym: "gibberellin 2beta-dioxygenase activity" EXACT [EC:1.14.11.13] synonym: "gibberellin 2beta-hydroxylase activity" EXACT [EC:1.14.11.13] xref: EC:1.14.11.13 xref: GO:0045543 xref: MetaCyc:GIBBERELLIN-2-BETA-DIOXYGENASE-RXN xref: MetaCyc:PWY-102 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006156 name: gibberellin 20-oxidase activity namespace: molecular_function def: "Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones." [PMID:7604047] xref: GO:0045544 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006157 name: syndecan binding namespace: molecular_function def: "Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells." [GOC:go_curators, http://cancerweb.ncl.ac.uk/] xref: GO:0045545 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006158 name: dehydrodolichyl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate." [PMID:9858571] xref: GO:0045547 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0006159 name: phenylalanine ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-phenylalanine = trans-cinnamate + NH3." [EC:4.3.1.5] synonym: "L-phenylalanine ammonia-lyase (trans-cinnamate-forming)" EXACT [EC:4.3.1.5] synonym: "L-phenylalanine ammonia-lyase activity" EXACT [EC:4.3.1.5] synonym: "L-tyrosine ammonia-lyase activity" EXACT [EC:4.3.1.5] synonym: "PAL" RELATED [EC:4.3.1.5] synonym: "phenylalanine ammonium-lyase activity" EXACT [EC:4.3.1.5] synonym: "phenylalanine deaminase activity" EXACT [EC:4.3.1.5] synonym: "tyrase activity" EXACT [EC:4.3.1.5] synonym: "tyrosine ammonia-lyase activity" EXACT [EC:4.3.1.5] xref: EC:4.3.1.5 xref: GO:0045548 xref: MetaCyc:PHENYLALANINE-AMMONIA-LYASE-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0006160 name: 9-cis-epoxycarotenoid dioxygenase activity namespace: molecular_function def: "Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal and 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al." [EC:1.13.11.51] synonym: "9-cis-epoxycarotenoid 11,12-dioxygenase activity" EXACT [EC:1.13.11.51] synonym: "AtNCED3" RELATED [EC:1.13.11.51] synonym: "NCED" RELATED [EC:1.13.11.51] synonym: "neoxanthin cleavage enzyme" BROAD [] synonym: "nine-cis-epoxycarotenoid dioxygenase activity" EXACT [EC:1.13.11.51] synonym: "PvNCED1" RELATED [EC:1.13.11.51] synonym: "VP14" RELATED [EC:1.13.11.51] xref: EC:1.13.11.51 xref: GO:0045549 is_a: CCO:F0002499 ! carotenoid dioxygenase activity [Term] id: CCO:F0006161 name: geranylgeranyl reductase activity namespace: molecular_function def: "Catalysis of the formation of phytyl moiety from the stepwise reduction of a geranylgeranyl moiety." [PMID:9492312] subset: gosubset_prok xref: GO:0045550 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006162 name: cinnamyl-alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+." [EC:1.1.1.195] synonym: "CAD activity" BROAD [EC:1.1.1.195] synonym: "cinnamyl alcohol dehydrogenase activity" EXACT [EC:1.1.1.195] synonym: "cinnamyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.195] xref: EC:1.1.1.195 xref: GO:0045551 xref: MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006163 name: dihydrokaempferol 4-reductase activity namespace: molecular_function def: "Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+." [EC:1.1.1.219] subset: gosubset_prok synonym: "cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.219] synonym: "dihydroflavanol 4-reductase activity" EXACT [EC:1.1.1.219] synonym: "dihydroflavonol 4-reductase activity" EXACT [EC:1.1.1.219] synonym: "dihydromyricetin reductase activity" EXACT [EC:1.1.1.219] synonym: "dihydroquercetin reductase activity" EXACT [EC:1.1.1.219] synonym: "NADPH-dihydromyricetin reductase activity" EXACT [EC:1.1.1.219] xref: EC:1.1.1.219 xref: GO:0045552 xref: MetaCyc:DIHYDROKAEMPFEROL-4-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006164 name: TRAIL binding namespace: molecular_function def: "Interacting selectively with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines." [GOC:go_curators, PMID:9082980] synonym: "Apo-2L binding" EXACT [] xref: GO:0045569 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006165 name: ketoreductase activity namespace: molecular_function def: "Catalysis of the reduction of a ketone group to form the corresponding alcohol." [EC:1.1.-.-] xref: EC:1.1.-.- xref: GO:0045703 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0006166 name: nutrient reservoir activity namespace: molecular_function def: "Functions in the storage of nutritious substrates." [GOC:ai] comment: Note that this term can be used in place of the obsolete terms 'storage protein ; GO:0005187' and 'storage protein of fat body (sensu Insecta) ; GO:0008041'. subset: goslim_generic subset: goslim_pir subset: gosubset_prok synonym: "storage protein" RELATED [] synonym: "storage protein of fat body (sensu Insecta)" RELATED [] synonym: "yolk protein" RELATED [] xref: GO:0045735 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0006167 name: precorrin-6Y C5,15-methyltransferase (decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2." [EC:2.1.1.132] subset: gosubset_prok synonym: "precorrin-6 methyltransferase activity" BROAD [EC:2.1.1.132] synonym: "precorrin-6Y methylase activity" BROAD [EC:2.1.1.132] synonym: "S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)" EXACT [EC:2.1.1.132] xref: EC:2.1.1.132 xref: GO:0046025 xref: MetaCyc:2.1.1.132-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0006168 name: precorrin-4 C11-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5." [EC:2.1.1.133] subset: gosubset_prok synonym: "CobM" RELATED [EC:2.1.1.133] synonym: "S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase activity" EXACT [EC:2.1.1.133] xref: EC:2.1.1.133 xref: GO:0046026 xref: MetaCyc:2.1.1.133-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0006169 name: phospholipid:diacylglycerol acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol." [EC:2.3.1.158] synonym: "PDAT activity" EXACT [EC:2.3.1.158] synonym: "phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase activity" EXACT [EC:2.3.1.158] xref: EC:2.3.1.158 xref: GO:0046027 xref: MetaCyc:2.3.1.158-RXN xref: Reactome:22783 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0006170 name: electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity namespace: molecular_function def: "Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II." [GOC:ai, ISBN:0716731363] synonym: "plastocyanin" NARROW [] xref: GO:0046028 is_a: CCO:F0002378 ! electron carrier activity [Term] id: CCO:F0006171 name: mannitol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannitol + NAD+ = D-mannose + NADH + H+." [EC:1.1.1.255] synonym: "mannitol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.255] synonym: "MTD activity" EXACT [EC:1.1.1.255] synonym: "NAD-dependent mannitol dehydrogenase activity" BROAD [EC:1.1.1.255] xref: EC:1.1.1.255 xref: GO:0046029 xref: MetaCyc:1.1.1.255-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor is_a: CCO:F0004651 ! hexitol dehydrogenase activity [Term] id: CCO:F0006172 name: inositol trisphosphate phosphatase activity namespace: molecular_function def: "Catalysis of the removal of one of the three phosphate groups of an inositol trisphosphate." [GOC:bf] synonym: "inositol-1,4,5-trisphosphate phosphatase" NARROW [] synonym: "IP(3) phosphatase activity" EXACT [] synonym: "IP3 phosphatase activity" EXACT [] xref: GO:0046030 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0006173 name: gluconokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-gluconate = ADP + 6-phospho-D-gluconate." [EC:2.7.1.12] subset: gosubset_prok synonym: "ATP:D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.12] synonym: "gluconate kinase activity" EXACT [EC:2.7.1.12] synonym: "gluconokinase (phosphorylating)" EXACT [EC:2.7.1.12] xref: EC:2.7.1.12 xref: GO:0046316 xref: MetaCyc:GLUCONOKIN-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006174 name: SMAD binding namespace: molecular_function def: "Interacting selectively with a SMAD signaling protein." [GOC:ai] xref: GO:0046332 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006175 name: aminoglycoside 3-N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring." [GOC:cb] subset: gosubset_prok synonym: "3'-aminoglycoside acetyltransferase activity" RELATED [EC:2.3.1.81] synonym: "3-N-aminoglycoside acetyltransferase activity" EXACT [EC:2.3.1.81] synonym: "acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity" EXACT [EC:2.3.1.81] synonym: "acetyl-CoA:gentamicin-C N3'-acetyltransferase activity" NARROW [EC:2.3.1.60] synonym: "aminoglycoside acetyltransferase AAC(3)-1" RELATED [EC:2.3.1.60] synonym: "aminoglycoside acetyltransferase AAC(3)-I activity" RELATED [EC:2.3.1.60] synonym: "gentamicin 3'-N-acetyltransferase activity" NARROW [] synonym: "gentamicin acetyltransferase I activity" NARROW [EC:2.3.1.60] synonym: "gentamicin-(3)-N-acetyltransferase activity" NARROW [EC:2.3.1.81] synonym: "gentamycin 3'-N-acetyltransferase activity" EXACT [] synonym: "gentamycin acetyltransferase I" RELATED [EC:2.3.1.60] xref: EC:2.3.1.60 xref: EC:2.3.1.81 xref: GO:0016991 xref: GO:0046353 xref: MetaCyc:AMINOGLYCOSIDE-N3 xref: MetaCyc:GENTAMICIN-3 is_a: CCO:F0005513 ! aminoglycoside N-acetyltransferase activity [Term] id: CCO:F0006176 name: polynucleotide 3'-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage." [EC:3.1.3.32] comment: Consider also annotating to the molecular function term 'damaged DNA binding ; GO:0003684'. synonym: "2'(3')-polynucleotidase activity" EXACT [EC:3.1.3.32] synonym: "5'-polynucleotidekinase 3'-phosphatase activity" EXACT [EC:3.1.3.32] synonym: "deoxyribonucleate 3'-phosphatase activity" EXACT [EC:3.1.3.32] synonym: "DNA 3'-phosphatase activity" EXACT [EC:3.1.3.32] synonym: "polynucleotide 3'-phosphohydrolase activity" EXACT [EC:3.1.3.32] xref: EC:3.1.3.32 xref: GO:0046403 xref: MetaCyc:POLYNUCLEOTIDE-3 is_a: CCO:F0004127 ! nucleotide phosphatase activity [Term] id: CCO:F0006177 name: ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA." [EC:2.7.1.78] synonym: "ATP-dependent DNA 5'-hydroxyl-kinase activity" EXACT [] synonym: "ATP-dependent DNA kinase activity" EXACT [] synonym: "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] synonym: "ATP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity" EXACT [] xref: EC:2.7.1.78 xref: GO:0046404 xref: MetaCyc:POLYNUCLEOTIDE-5 is_a: CCO:F0008169 ! polydeoxyribonucleotide kinase activity is_a: CCO:F0008170 ! ATP-dependent polynucleotide kinase activity [Term] id: CCO:F0006178 name: glycerol dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O." [EC:4.2.1.30] subset: gosubset_prok synonym: "glycerol dehydrase activity" EXACT [EC:4.2.1.30] synonym: "glycerol hydro-lyase (3-hydroxypropanal-forming)" EXACT [EC:4.2.1.30] synonym: "glycerol hydro-lyase activity" EXACT [EC:4.2.1.30] xref: EC:4.2.1.30 xref: GO:0046405 xref: MetaCyc:GLYCEROL-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006179 name: magnesium protoporphyrin IX methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + magnesium protoporphyrin = S-adenosyl-L-homocysteine + magnesium protoporphyrin monomethyl ester." [EC:2.1.1.11] subset: gosubset_prok synonym: "(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase activity" EXACT [EC:2.1.1.11] synonym: "magnesium-protoporphyrin O-methyltransferase activity" EXACT [] synonym: "Mg-protoporphyrin IX methyltransferase activity" EXACT [EC:2.1.1.11] synonym: "S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase activity" EXACT [EC:2.1.1.11] synonym: "S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase activity" EXACT [EC:2.1.1.11] synonym: "S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase activity" EXACT [EC:2.1.1.11] synonym: "S-adenosylmethionine-magnesium protoporphyrin methyltransferase activity" EXACT [EC:2.1.1.11] synonym: "S-adenosylmethioninemagnesium protoporphyrin methyltransferase activity" EXACT [EC:2.1.1.11] xref: EC:2.1.1.11 xref: GO:0046406 xref: MetaCyc:RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN is_a: CCO:F0001758 ! O-methyltransferase activity is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0006180 name: chlorophyll synthetase activity namespace: molecular_function def: "Catalysis of the esterification reaction: chlorophyllide a + phytyl pyrophosphate = chlorophyll a + pyrophosphate." [ISBN:0471331309 "Biochemical Pathways", PMID:8552034] xref: GO:0046408 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0006181 name: p-coumarate 3-hydroxylase activity namespace: molecular_function def: "Catalysis of the 3-hydroxylation reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H20 + NADP+." [PMID:11429408, PMID:11891223] synonym: "cytochrome P450 CYP98A3" NARROW [] xref: GO:0046409 is_a: CCO:F0000894 ! monooxygenase activity [Term] id: CCO:F0006182 name: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + isochorismate = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate + CO2." [EC:2.5.1.64, PMID:1459959] subset: gosubset_prok synonym: "2-oxoglutarate decarboxylase/SHCHC synthase activity" EXACT [EC:2.5.1.64] synonym: "2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase--alpha-ketoglutarate decarboxylase activity" EXACT [EC:2.5.1.64] synonym: "2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity" EXACT [EC:2.5.1.64] synonym: "6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity" EXACT [EC:2.5.1.64] synonym: "isochorismate:2-oxoglutarate:cyclodienyltransferase (decarboxylating, pyruvate-forming)" EXACT [EC:2.5.1.64] synonym: "SHCHC synthase activity" EXACT [EC:2.5.1.64] xref: EC:2.5.1.64 xref: GO:0046410 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0006183 name: methylisocitrate lyase activity namespace: molecular_function def: "Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate." [EC:4.1.3.30] subset: gosubset_prok synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)" EXACT [EC:4.1.3.30] synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase activity" EXACT [EC:4.1.3.30] synonym: "2-methylisocitrate lyase activity" EXACT [] synonym: "MICL" RELATED [EC:4.1.3.30] xref: EC:4.1.3.30 xref: GO:0046421 xref: MetaCyc:METHYLISOCITRATE-LYASE-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0006184 name: violaxanthin de-epoxidase activity namespace: molecular_function def: "Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; also antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O." [EC:1.10.99.3, GOC:ai, ISBN:0471331309 "Biochemical Pathways"] synonym: "VDE" RELATED [EC:1.10.99.3] synonym: "violaxanthin:ascorbate oxidoreductase activity" EXACT [EC:1.10.99.3] xref: EC:1.10.99.3 xref: GO:0046422 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006185 name: allene-oxide cyclase activity namespace: molecular_function def: "Catalysis of the reaction: (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate." [EC:5.3.99.6] synonym: "(9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing)" EXACT [EC:5.3.99.6] xref: EC:5.3.99.6 xref: GO:0046423 xref: MetaCyc:ALLENE-OXIDE-CYCLASE-RXN is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0006186 name: ferulate 5-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+." [PMID:8692910, PMID:9880351] xref: GO:0046424 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0006187 name: 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + pyrophosphate + CO2." [MetaCyc:DMK-RXN] synonym: "1,4-Dihydroxy-2-naphtoate prenyltransferase activity" EXACT [] xref: EC:2.5.1.- xref: GO:0046428 xref: MetaCyc:DMK-RXN is_a: CCO:F0000268 ! polyprenyltransferase activity [Term] id: CCO:F0006188 name: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + protein-disulfide = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + protein-dithiol. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative way of naming 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate." [EC:1.17.4.3, PMID:11752431] subset: gosubset_prok synonym: "(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:protein-disulfide oxidoreductase (hydrating)" EXACT [EC:1.17.4.3] synonym: "1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity" EXACT [] synonym: "1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase activity" EXACT [EC:1.17.4.3] xref: EC:1.17.4.3 xref: GO:0046429 is_a: CCO:F0003310 ! oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor [Term] id: CCO:F0006189 name: galactolipid galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol." [EC:2.4.1.184] synonym: "3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.184] synonym: "DGDG synthase activity" BROAD [EC:2.4.1.184] synonym: "digalactosyldiacylglycerol synthase activity" BROAD [EC:2.4.1.184] synonym: "galactolipid-galactolipid galactosyltransferase activity" EXACT [EC:2.4.1.184] synonym: "galactolipid:galactolipid galactosyltransferase activity" EXACT [] synonym: "GGGT activity" EXACT [EC:2.4.1.184] synonym: "interlipid galactosyltransferase activity" RELATED [EC:2.4.1.184] xref: EC:2.4.1.184 xref: GO:0046480 xref: MetaCyc:RXN-1226 is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0006190 name: digalactosyldiacylglycerol synthase namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol = UDP + 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol." [EC:2.4.1.241, MetaCyc:RXN-1225] synonym: "DGD1" NARROW [] synonym: "DGD2" NARROW [] synonym: "DGDG synthase activity" BROAD [EC:2.4.1.241] synonym: "UDP-galactose-dependent DGDG synthase activity" EXACT [EC:2.4.1.241] synonym: "UDP-galactose-dependent digalactosyldiacylglycerol synthase activity" EXACT [EC:2.4.1.241] synonym: "UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.241] synonym: "UDP-galactose:MGDG galactosyltransferase activity" EXACT [] xref: EC:2.4.1.241 xref: GO:0046481 xref: MetaCyc:RXN-1225 is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006191 name: UDPsulfoquinovose synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + SO3(2-) (sulfite) = UDP-6-sulfoquinovose + H2O." [EC:3.13.1.1] synonym: "sulfite:UDP-glucose sulfotransferase activity" EXACT [] synonym: "UDP-6-sulfo-6-deoxyglucose sulfohydrolase activity" EXACT [EC:3.13.1.1] synonym: "UDP-sulfoquinovose synthase activity" EXACT [EC:3.13.1.1] synonym: "UDPsulphoquinovose synthase activity" EXACT [] xref: EC:3.13.1.1 xref: GO:0046507 xref: MetaCyc:RXN-1223 is_a: CCO:F0006192 ! hydrolase activity, acting on carbon-sulfur bonds [Term] id: CCO:F0006192 name: hydrolase activity, acting on carbon-sulfur bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any carbon-sulfur bond, C-S." [GOC:jl] subset: gosubset_prok synonym: "hydrolase activity, acting on carbon-sulphur bonds" EXACT [] xref: EC:3.13 xref: GO:0046508 is_a: CCO:F0003359 ! hydrolase activity [Term] id: CCO:F0006193 name: 1,2-diacylglycerol 3-beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + 1,2-diacylglycerol = UDP + 3-beta-D-galactosyl-1,2-diacylglycerol." [EC:2.4.1.46] synonym: "1-beta-MGDG activity" EXACT [EC:2.4.1.46] synonym: "1beta-MGDG" RELATED [EC:2.4.1.46] synonym: "MGDG synthase activity" EXACT [] synonym: "monogalactosyldiacylglycerol synthase activity" EXACT [] synonym: "UDP galactose-1,2-diacylglycerol galactosyltransferase activity" EXACT [] synonym: "UDP-galactose-diacylglyceride galactosyltransferase activity" EXACT [] synonym: "UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.46] synonym: "UDP-galactose:diacylglycerol galactosyltransferase activity" EXACT [] synonym: "UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.46] synonym: "uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase activity" EXACT [] xref: EC:2.4.1.46 xref: GO:0046509 xref: MetaCyc:2.4.1.46-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006194 name: UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP." [MetaCyc:RXN-1224] synonym: "sulfolipid synthase" BROAD [] synonym: "UDP-sulphoquinovose:DAG sulphoquinovosyltransferase activity" EXACT [] xref: GO:0046510 xref: MetaCyc:RXN-1224 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006195 name: S-methyl-5-thioribose kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + S5-methyl-5-thio-D-ribose = ADP + S5-methyl-5-thio-D-ribose 1-phosphate." [EC:2.7.1.100] subset: gosubset_prok synonym: "5-methylthioribose kinase (phosphorylating)" EXACT [EC:2.7.1.100] synonym: "5-methylthioribose kinase activity" EXACT [] synonym: "ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase activity" EXACT [EC:2.7.1.100] synonym: "ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase activity" EXACT [EC:2.7.1.100] synonym: "methylthioribose kinase activity" EXACT [EC:2.7.1.100] synonym: "MTR kinase activity" EXACT [EC:2.7.1.100] xref: EC:2.7.1.100 xref: GO:0046522 xref: MetaCyc:5-METHYLTHIORIBOSE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006196 name: S-methyl-5-thioribose-1-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 5-methylthio-5-deoxy-D-ribose 1-phosphate = 5-methylthio-5-deoxy-D-ribulose 1-phosphate." [EC:5.3.1.23] subset: gosubset_prok synonym: "1-phospho-5'-S-methylthioribose isomerase activity" EXACT [EC:5.3.1.23] synonym: "1-PMTR isomerase activity" EXACT [EC:5.3.1.23] synonym: "5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.23] synonym: "5-methylthioribose-1-phosphate isomerase activity" EXACT [] synonym: "methylthioribose 1-phosphate isomerase activity" EXACT [EC:5.3.1.23] synonym: "MTR-1-P isomerase activity" EXACT [EC:5.3.1.23] synonym: "S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.23] synonym: "S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.23] synonym: "S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.23] synonym: "S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.23] xref: EC:5.3.1.23 xref: GO:0046523 xref: MetaCyc:5.3.1.23-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0006197 name: sucrose-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate." [EC:2.4.1.14] subset: gosubset_prok synonym: "SPS" RELATED [EC:2.4.1.14] synonym: "sucrose 6-phosphate synthase activity" EXACT [EC:2.4.1.14] synonym: "sucrose phosphate synthetase activity" EXACT [EC:2.4.1.14] synonym: "sucrose phosphate-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] synonym: "sucrosephosphate-UDP glucosyltransferase activity" EXACT [EC:2.4.1.14] synonym: "UDP-glucose-fructose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] synonym: "UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.14] synonym: "UDPglucose-fructose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] synonym: "UDPglucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.14] synonym: "uridine diphosphoglucose-fructose phosphate glucosyltransferase activity" EXACT [EC:2.4.1.14] xref: EC:2.4.1.14 xref: GO:0046524 xref: MetaCyc:SUCROSE-PHOSPHATE-SYNTHASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006198 name: xylosylprotein 4-beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein." [EC:2.4.1.133] synonym: "galactosyltransferase I activity" RELATED [EC:2.4.1.133] synonym: "UDP-D-galactose:D-xylose galactosyltransferase activity" EXACT [EC:2.4.1.133] synonym: "UDP-D-galactose:xylose galactosyltransferase activity" EXACT [EC:2.4.1.133] synonym: "UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.133] synonym: "UDP-galactose:xylose galactosyltransferase activity" EXACT [] synonym: "UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.133] synonym: "uridine diphosphogalactose-xylose galactosyltransferase activity" EXACT [EC:2.4.1.133] xref: EC:2.4.1.133 xref: GO:0046525 xref: MetaCyc:2.4.1.133-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006199 name: D-xylulose reductase activity namespace: molecular_function def: "Catalysis of the reaction: xylitol + NAD+ = D-xylulose + NADH + H+." [EC:1.1.1.9] subset: gosubset_prok synonym: "xylitol dehydrogenase activity" EXACT [EC:1.1.1.9] xref: EC:1.1.1.9 xref: GO:0046526 xref: MetaCyc:D-XYLULOSE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor is_a: CCO:F0004651 ! hexitol dehydrogenase activity [Term] id: CCO:F0006200 name: glucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: EC:2.4.1.- xref: GO:0046527 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006201 name: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate without requiring the cofactor 2,3-bisphosphoglycerate." [EC:5.4.2.1] subset: gosubset_prok synonym: "PGAM-i" RELATED [EC:5.4.2.1] xref: GO:0046537 is_a: CCO:F0000998 ! phosphoglycerate mutase activity [Term] id: CCO:F0006202 name: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; requires the cofactor 2,3-bisphosphoglycerate." [EC:5.4.2.1] subset: gosubset_prok synonym: "glycerate phosphomutase (diphosphoglycerate cofactor) activity" EXACT [EC:5.4.2.1] synonym: "PGAM-d" RELATED [EC:5.4.2.1] xref: GO:0046538 is_a: CCO:F0000998 ! phosphoglycerate mutase activity [Term] id: CCO:F0006203 name: histamine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + Nt-methylhistamine." [EC:2.1.1.8] synonym: "histamine 1-methyltransferase activity" EXACT [EC:2.1.1.8] synonym: "histamine methyltransferase activity" EXACT [EC:2.1.1.8] synonym: "histamine-methylating enzyme" RELATED [EC:2.1.1.8] synonym: "imidazolemethyltransferase activity" EXACT [EC:2.1.1.8] synonym: "S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity" EXACT [EC:2.1.1.8] synonym: "S-adenosylmethionine-histamine N-methyltransferase activity" EXACT [EC:2.1.1.8] xref: EC:2.1.1.8 xref: GO:0046539 xref: MetaCyc:HISTAMINE-N-METHYLTRANSFERASE-RXN is_a: CCO:F0001757 ! N-methyltransferase activity [Term] id: CCO:F0006204 name: trans-aconitate 3-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate." [EC:2.1.1.145] synonym: "S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase activity" EXACT [EC:2.1.1.145] xref: EC:2.1.1.145 xref: GO:0046547 xref: MetaCyc:2.1.1.145-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0006205 name: D-malate dehydrogenase (decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-malate + NAD+ = pyruvate + CO2 + NADH + H+." [EC:1.1.1.83] synonym: "(R)-malate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.83] synonym: "bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating)" RELATED [EC:1.1.1.83] synonym: "D-malate dehydrogenase activity" EXACT [EC:1.1.1.83] synonym: "D-malic enzyme" RELATED [EC:1.1.1.83] xref: EC:1.1.1.83 xref: GO:0046553 xref: MetaCyc:1.1.1.83-RXN is_a: CCO:F0003217 ! malate dehydrogenase activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006206 name: malate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+." [EC:1.1.1.82] subset: gosubset_prok synonym: "(S)-malate:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.82] synonym: "malate NADP dehydrogenase activity" EXACT [EC:1.1.1.82] synonym: "malic dehydrogenase (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.82] synonym: "NADP malate dehydrogenase activity" EXACT [EC:1.1.1.82] synonym: "NADP-linked malate dehydrogenase activity" EXACT [EC:1.1.1.82] synonym: "NADP-malate dehydrogenase activity" EXACT [EC:1.1.1.82] xref: EC:1.1.1.82 xref: GO:0046554 xref: MetaCyc:MALATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003217 ! malate dehydrogenase activity is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006207 name: acetylxylan esterase activity namespace: molecular_function def: "Catalysis of the deacetylation of xylans and xylo-oligosaccharides." [EC:3.1.1.72] subset: gosubset_prok xref: EC:3.1.1.72 xref: GO:0046555 xref: MetaCyc:3.1.1.72-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006208 name: alpha-N-arabinofuranosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides." [EC:3.2.1.55] subset: gosubset_prok synonym: "alpha-arabinofuranosidase activity" EXACT [EC:3.2.1.55] synonym: "alpha-arabinosidase activity" EXACT [EC:3.2.1.55] synonym: "alpha-L-arabinanase activity" EXACT [EC:3.2.1.55] synonym: "alpha-L-arabinofuranosidase activity" EXACT [] synonym: "alpha-L-arabinofuranoside arabinofuranohydrolase activity" EXACT [EC:3.2.1.55] synonym: "alpha-L-arabinofuranoside hydrolase activity" EXACT [EC:3.2.1.55] synonym: "alpha-L-arabinosidase activity" EXACT [EC:3.2.1.55] synonym: "arabinofuranosidase activity" EXACT [EC:3.2.1.55] synonym: "arabinosidase activity" EXACT [EC:3.2.1.55] synonym: "L-arabinosidase activity" EXACT [EC:3.2.1.55] synonym: "polysaccharide alpha-L-arabinofuranosidase activity" EXACT [] xref: EC:3.2.1.55 xref: GO:0046556 xref: MetaCyc:3.2.1.55-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006209 name: glucan endo-1,6-beta-glucosidase activity namespace: molecular_function def: "Catalysis of the random hydrolysis of 1,6-linkages in 1,6-beta-D-glucans." [EC:3.2.1.75] synonym: "1,6-beta-D-glucan glucanohydrolase activity" EXACT [EC:3.2.1.75] synonym: "beta-1,6-glucan 6-glucanohydrolase activity" EXACT [EC:3.2.1.75] synonym: "beta-1,6-glucan hydrolase activity" EXACT [EC:3.2.1.75] synonym: "beta-1,6-glucanase activity" EXACT [EC:3.2.1.75] synonym: "beta-1,6-glucanase-pustulanase activity" EXACT [EC:3.2.1.75] synonym: "beta-1->6-glucan hydrolase activity" EXACT [EC:3.2.1.75] synonym: "endo-(1,6)-beta-D-glucanase activity" EXACT [] synonym: "endo-(1->6)-beta-D-glucanase activity" EXACT [EC:3.2.1.75] synonym: "endo-1,6-beta-D-glucanase activity" EXACT [EC:3.2.1.75] synonym: "endo-1,6-beta-glucanase activity" EXACT [EC:3.2.1.75] synonym: "endo-beta-1,6-glucanase activity" EXACT [EC:3.2.1.75] xref: EC:3.2.1.75 xref: GO:0046557 xref: MetaCyc:3.2.1.75-RXN is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0006210 name: arabinan endo-1,5-alpha-L-arabinosidase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of 1,5-alpha-arabinofuranosidic linkages in 1,5-arabinans." [EC:3.2.1.99] subset: gosubset_prok synonym: "1,5-alpha-L-arabinan 1,5-alpha-L-arabinanohydrolase activity" EXACT [EC:3.2.1.99] synonym: "endo-1,5-a-L-arabinanase activity" EXACT [] synonym: "endo-1,5-alpha-L-arabinanase activity" EXACT [EC:3.2.1.99] synonym: "endo-alpha-1,5-arabanase activity" EXACT [EC:3.2.1.99] synonym: "endo-arabanase activity" EXACT [EC:3.2.1.99] xref: EC:3.2.1.99 xref: GO:0046558 xref: MetaCyc:3.2.1.99-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006211 name: alpha-glucuronidase activity namespace: molecular_function def: "Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate." [EC:3.2.1.139] subset: gosubset_prok synonym: "alpha-D-glucosiduronate glucuronohydrolase activity" EXACT [EC:3.2.1.139] synonym: "alpha-glucosiduronase activity" EXACT [EC:3.2.1.139] xref: EC:3.2.1.139 xref: GO:0046559 xref: MetaCyc:3.2.1.139-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006212 name: scytalidopepsin B activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins with broad specificity, cleaving Phe24-Phe, but not Leu15-Tyr and Phe25-Tyr in the B chain of insulin." [EC:3.4.23.32] synonym: "Ganoderma lucidum aspartic proteinase activity" EXACT [EC:3.4.23.32] synonym: "Ganoderma lucidum carboxyl proteinase activity" EXACT [EC:3.4.23.32] synonym: "Scytalidium aspartic proteinase B activity" RELATED [EC:3.4.23.32] synonym: "Scytalidium lignicolum aspartic proteinase B" RELATED [EC:3.4.23.32] synonym: "SLB" RELATED [EC:3.4.23.32] xref: EC:3.4.23.32 xref: GO:0046560 xref: MetaCyc:3.4.23.32-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0006213 name: penicillopepsin activity namespace: molecular_function def: "Catalysis of the hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving Gly20-Glu in the B chain of insulin. Clots milk, and activates trypsinogen." [EC:3.4.23.20] synonym: "acid protease A" EXACT [] synonym: "Penicillium aspartic proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium caseicolum aspartic proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium citrinum acid proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium citrinum aspartic proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium cyclopium acid proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium duponti aspartic proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium expansum acid proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium expansum aspartic proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium janthinellum acid proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium janthinellum aspartic protease activity" EXACT [EC:3.4.23.20] synonym: "Penicillium janthinellum aspartic proteinase activity" EXACT [EC:3.4.23.20] synonym: "Penicillium roqueforti acid proteinase activity" EXACT [EC:3.4.23.20] synonym: "peptidase A activity" BROAD [EC:3.4.23.20] xref: EC:3.4.23.20 xref: GO:0046561 xref: MetaCyc:3.4.23.20-RXN is_a: CCO:F0000659 ! aspartic-type endopeptidase activity [Term] id: CCO:F0006214 name: glucose oxidase activity namespace: molecular_function def: "Catalysis of the reaction: a hexose + O2 = a hexno-1,5-lactone + H2O2; includes beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2." [EC:1.1.3.4, GOC:mah] synonym: "beta-D-glucose oxidase activity" EXACT [] synonym: "beta-D-glucose:oxygen 1-oxido-reductase activity" EXACT [EC:1.1.3.4] synonym: "beta-D-glucose:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.4] synonym: "beta-D-glucose:quinone oxidoreductase activity" EXACT [EC:1.1.3.4] synonym: "corylophyline" RELATED [EC:1.1.3.4] synonym: "D-glucose oxidase activity" EXACT [EC:1.1.3.4] synonym: "D-glucose-1-oxidase activity" EXACT [EC:1.1.3.4] synonym: "deoxin-1" RELATED [EC:1.1.3.4] synonym: "glucose aerodehydrogenase activity" EXACT [EC:1.1.3.4] synonym: "glucose oxyhydrase activity" EXACT [EC:1.1.3.4] synonym: "GOD activity" RELATED [EC:1.1.3.4] synonym: "microcid" RELATED [EC:1.1.3.4] synonym: "penatin" RELATED [EC:1.1.3.4] xref: EC:1.1.3.4 xref: GO:0046562 xref: MetaCyc:GLUCOSE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0006215 name: methanol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde." [MetaCyc:METHANOL-OXIDASE-RXN] comment: Note that EC:1.1.3.31 was deleted from EC as it cannot be distinguished from alcohol oxidase (EC:1.1.3.13). xref: EC:1.1.3.- xref: GO:0046563 xref: MetaCyc:METHANOL-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0006216 name: oxalate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: oxalate = formate + CO2." [EC:4.1.1.2] subset: gosubset_prok synonym: "oxalate carboxy-lyase (formate-forming)" EXACT [EC:4.1.1.2] synonym: "oxalate carboxy-lyase activity" EXACT [EC:4.1.1.2] xref: EC:4.1.1.2 xref: GO:0046564 xref: MetaCyc:OXALATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006217 name: 3-dehydroshikimate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate (protocatechuate) + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate." [EC:4.2.1.-, MetaCyc:DHSHIKIMATE-DEHYDRO-RXN] xref: EC:4.2.1.- xref: GO:0046565 xref: MetaCyc:DHSHIKIMATE-DEHYDRO-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006218 name: DOPA dioxygenase activity namespace: molecular_function def: "Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid." [PMID:11711071] synonym: "dihydroxyphenylalanine dioxygenase activity" EXACT [] xref: GO:0046566 is_a: CCO:F0008070 ! dioxygenase activity [Term] id: CCO:F0006219 name: aphidicolan-16 beta-ol synthase activity namespace: molecular_function def: "Catalysis of the formation of aphidicolan-16 beta-ol from geranylgeranyl diphosphate." [PMID:12149019] xref: GO:0046567 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0006220 name: 3-methylbutanal reductase activity namespace: molecular_function def: "Catalysis of the reaction: isoamyl alcohol (3-methylbutanol) + NADP+ = isovaleraldehyde (3-methylbutanal) + NADPH + H+." [EC:1.1.1.265] synonym: "3-methylbutanol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.265] synonym: "3-methylbutyraldehyde reductase activity" EXACT [] synonym: "isoamyl alcohol oxidase activity" EXACT [] xref: EC:1.1.1.265 xref: GO:0046568 xref: MetaCyc:1.1.1.265-RXN is_a: CCO:F0000510 ! aldehyde reductase activity [Term] id: CCO:F0006221 name: glyoxal oxidase activity namespace: molecular_function def: "Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2." [EC:1.2.3.-, PMID:11733005] synonym: "GLOX" EXACT [] xref: EC:1.2.3.- xref: GO:0046569 is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0006222 name: 5-methylthioribulose-1-phosphate 4-dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: methylthioribulose-1-phosphate = 2,3-diketo-5-methylthio-1-phosphopentane + H2O." [MetaCyc:R145-RXN] xref: GO:0046570 xref: MetaCyc:R145-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006223 name: aspartate-2-keto-4-methylthiobutyrate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate." [MetaCyc:R15-RXN] xref: EC:2.6.1.- xref: GO:0046571 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006224 name: versicolorin B synthase activity namespace: molecular_function def: "Catalysis of the ring closure reaction: versiconal hemiacetal = versicolorin B + H2O." [PMID:8784203] xref: GO:0046572 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0006225 name: lactonohydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group." [PMID:11640988] xref: GO:0046573 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006226 name: glycuronidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid." [PMID:10441389, PMID:12044176] synonym: "glucuronyl hydrolase activity" EXACT [] xref: GO:0046574 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006227 name: rhamnogalacturonan acetylesterase activity namespace: molecular_function def: "Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan." [PMID:10801485] xref: GO:0046575 is_a: CCO:F0001731 ! acetylesterase activity [Term] id: CCO:F0006228 name: rhamnogalacturonase B activity namespace: molecular_function def: "Catalysis of the cleavage of (1,2)-alpha-L-Rhap-(1,4)-alpha-D-GalpA glycosidic linkage, generating oligosaccharides terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue." [PMID:8587995, PMID:8720076] xref: GO:0046576 is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006229 name: long-chain-alcohol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O." [EC:1.1.3.20] synonym: "fatty alcohol oxidase activity" EXACT [] synonym: "fatty alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.20] synonym: "long-chain fatty acid oxidase activity" EXACT [EC:1.1.3.20] synonym: "long-chain fatty alcohol oxidase activity" EXACT [] synonym: "long-chain-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.20] xref: EC:1.1.3.20 xref: GO:0046577 xref: MetaCyc:LONG-CHAIN-ALCOHOL-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0006230 name: Rap GTPase activator activity namespace: molecular_function def: "Increases the rate of GTP hydrolysis by a GTPase of the Rap family." [GOC:mah] xref: GO:0046582 is_a: CCO:F0001404 ! Ras GTPase activator activity [Term] id: CCO:F0006231 name: cation efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "cation efflux permease activity" EXACT [] xref: GO:0046583 is_a: CCO:F0001835 ! cation transmembrane transporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity [Term] id: CCO:F0006232 name: ribonuclease T1 activity namespace: molecular_function def: "Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates." [EC:3.1.27.3] subset: gosubset_prok synonym: "Aspergillus oryzae ribonuclease activity" NARROW [EC:3.1.27.3] synonym: "binase activity" EXACT [EC:3.1.27.3] synonym: "guanyl-specific RNase activity" EXACT [EC:3.1.27.3] synonym: "guanyloribonuclease activity" EXACT [EC:3.1.27.3] synonym: "ribonuclease C2" RELATED [EC:3.1.27.3] synonym: "ribonuclease Ch" RELATED [EC:3.1.27.3] synonym: "ribonuclease F1" EXACT [] synonym: "ribonuclease guaninenucleotido-2'-transferase (cyclizing)" EXACT [EC:3.1.27.3] synonym: "ribonuclease N1" RELATED [EC:3.1.27.3] synonym: "ribonuclease N3" RELATED [EC:3.1.27.3] synonym: "ribonuclease PP1" RELATED [EC:3.1.27.3] synonym: "ribonuclease SA" RELATED [EC:3.1.27.3] synonym: "ribonuclease U1" RELATED [EC:3.1.27.3] synonym: "RNase F1" RELATED [EC:3.1.27.3] synonym: "RNase G" RELATED [EC:3.1.27.3] synonym: "RNase N1 activity" EXACT [EC:3.1.27.3] synonym: "RNase N2 activity" EXACT [EC:3.1.27.3] synonym: "RNase Sa" RELATED [EC:3.1.27.3] synonym: "RNase T1" RELATED [EC:3.1.27.3] synonym: "RNase T1 activity" EXACT [] xref: EC:3.1.27.3 xref: GO:0046589 xref: MetaCyc:3.1.27.3-RXN is_a: CCO:F0000934 ! ribonuclease activity [Term] id: CCO:F0006233 name: polyamine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: N1-acetylspermine + O2 + H2O = N1-acetylspermidine + 3-aminopropanal + H2O2." [EC:1.5.3.11] synonym: "1-N-acetylspermidine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.5.3.11] synonym: "N1-acetylspermidine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.5.3.11] xref: EC:1.5.3.11 xref: GO:0046592 xref: MetaCyc:POLYAMINE-OXIDASE-RXN xref: Reactome:25469 is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0006234 name: mandelonitrile lyase activity namespace: molecular_function def: "Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde." [EC:4.1.2.10] synonym: "(R)-oxynitrilase activity" EXACT [EC:4.1.2.10] synonym: "D-alpha-hydroxynitrile lyase activity" EXACT [EC:4.1.2.10] synonym: "D-oxynitrilase activity" EXACT [EC:4.1.2.10] synonym: "hydroxynitrile lyase activity" BROAD [] synonym: "mandelonitrile benzaldehyde-lyase (cyanide-forming)" EXACT [EC:4.1.2.10] synonym: "mandelonitrile benzaldehyde-lyase activity" EXACT [EC:4.1.2.10] xref: EC:4.1.2.10 xref: GO:0046593 xref: MetaCyc:MANDELONITRILE-LYASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006235 name: carotenoid isomerase activity namespace: molecular_function def: "Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids." [PMID:11884677] xref: GO:0046608 is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0006236 name: voltage-gated sulfate antiporter activity namespace: molecular_function synonym: "prestin" NARROW [] synonym: "voltage gated sulfate antiporter activity" EXACT [] synonym: "voltage-dependent sulfate antiporter activity" EXACT [] synonym: "voltage-sensitive sulfate antiporter activity" EXACT [] synonym: "voltage-sensitive sulphate antiporter activity" EXACT [] xref: GO:0046609 is_a: CCO:F0002746 ! antiporter activity [Term] id: CCO:F0006237 name: sphingolipid-translocating ATPase activity namespace: molecular_function def: "Catalysis of the movement of sphingolipids from one membrane face to the other ('flippase' activity), driven by the hydrolysis of ATP." [GOC:ai, PMID:12034738] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "sphingolipid flippase activity" EXACT [] xref: GO:0046623 is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances is_a: CCO:F0006238 ! sphingolipid transporter activity [Term] id: CCO:F0006238 name: sphingolipid transporter activity namespace: molecular_function def: "Enables the directed movement of sphingolipids into, out of, within or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0046624 is_a: CCO:F0001556 ! lipid transporter activity [Term] id: CCO:F0006239 name: sphingolipid binding namespace: molecular_function def: "Interacting selectively with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0046625 is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0006240 name: digestive hormone activity namespace: molecular_function def: "A hormone that takes part in the digestion process." [GOC:ai] synonym: "secretin (sensu Mammalia)" NARROW [] xref: GO:0046659 is_a: CCO:F0001479 ! hormone activity [Term] id: CCO:F0006241 name: galactoside 6-L-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside." [PMID:12413479] xref: GO:0046702 is_a: CCO:F0006273 ! alpha(1,6)-fucosyltransferase activity [Term] id: CCO:F0006242 name: natural killer cell lectin-like receptor binding namespace: molecular_function def: "Interacting selectively with a lectin-like natural killer cell receptor." [GOC:ai] synonym: "KLRC4 receptor binding" NARROW [] synonym: "NK cell lectin-like receptor binding" EXACT [] synonym: "NKG2D receptor binding" NARROW [] xref: GO:0046703 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0006243 name: boron binding namespace: molecular_function def: "Interacting selectively with boron, the group 13 element with properties which are borderline between metals and non-metals." [http://www.webelements.com/] subset: gosubset_prok xref: GO:0046714 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0006244 name: boron transporter activity namespace: molecular_function def: "Catalysis of the transport of boron across a membrane against the concentration gradient." [PMID:12447444] subset: gosubset_prok synonym: "efflux-type boron transporter" NARROW [] xref: GO:0046715 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0006245 name: host cell surface receptor binding namespace: molecular_function def: "Interacting selectively with a receptor on the host cell surface." [GOC:ai, PMID:11511370] subset: gosubset_prok synonym: "cell surface antigen activity, host-interacting" RELATED [] synonym: "cell surface receptor ligand" RELATED [] xref: GO:0046789 is_a: CCO:F0001407 ! receptor binding is_a: CCO:F0006249 ! host cell surface binding [Term] id: CCO:F0006246 name: virion binding namespace: molecular_function def: "Interacting selectively with a virion, either by binding to components of the capsid or the viral envelope." [GOC:ai] xref: GO:0046790 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0006247 name: host cell extracellular matrix binding namespace: molecular_function def: "Interacting selectively with the extracellular matrix of a host cell." [PMID:7996163] subset: gosubset_prok xref: GO:0046810 is_a: CCO:F0008024 ! extracellular matrix binding [Term] id: CCO:F0006248 name: histone deacetylase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes." [GOC:ai, PMID:10482575] xref: GO:0046811 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0005557 ! histone deacetylase regulator activity [Term] id: CCO:F0006249 name: host cell surface binding namespace: molecular_function def: "Interacting selectively with the surface of a host cell." [GOC:ai] subset: goslim_pir subset: gosubset_prok xref: GO:0046812 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0006250 name: chemokine receptor antagonist activity namespace: molecular_function def: "Interacts with chemokine receptors to reduce the action of a chemokine." [GOC:ai, ISBN:0781718325] xref: GO:0046817 is_a: CCO:F0007301 ! receptor antagonist activity [Term] id: CCO:F0006251 name: 4-amino-4-deoxychorismate synthase activity namespace: molecular_function def: "Catalysis of the reaction: chorismate + glutamine = 4-amino-4-deoxychorismic acid + glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate." [GOC:krc, PMID:11495989, PMID:8346682] comment: Note that the name 'para-aminobenzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate. subset: gosubset_prok synonym: "ADC synthase activity" EXACT [EC:6.3.5.8] synonym: "aminodeoxychorismate synthase activity" RELATED [] synonym: "chorismate:L-glutamine amido-ligase activity" EXACT [EC:6.3.5.8] synonym: "p-aminobenzoate synthetase" RELATED [] synonym: "PabB activity" RELATED [EC:6.3.5.8] synonym: "para-aminobenzoic acid (PABA) synthase" RELATED [] synonym: "para-aminobenzoic acid synthase activity" RELATED [] xref: EC:6.3.5.8 xref: GO:0046820 xref: MetaCyc:PABASYN-RXN is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0006252 name: hydroxyapatite binding namespace: molecular_function def: "Interacting selectively with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentine." [http://cancerweb.ncl.ac.uk/] xref: GO:0046848 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0006253 name: oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP." [GOC:jl] subset: gosubset_prok xref: EC:1.7.1 xref: GO:0046857 is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0006254 name: ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity namespace: molecular_function def: "Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate." [PMID:10430961, PMID:10965036, PMID:2404515] comment: See also the molecular function term 'ribulose-bisphosphate carboxylase activity ; GO:0016984'. synonym: "rubisco activase activity" EXACT [] synonym: "rubisco activator" EXACT [] xref: GO:0046863 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0006255 name: cadmium ion binding namespace: molecular_function def: "Interacting selectively with cadmium (Cd) ions." [GOC:ai] subset: gosubset_prok synonym: "cadmium binding" EXACT [] synonym: "copper/cadmium binding" BROAD [] xref: GO:0046870 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0006256 name: N-acetylgalactosamine binding namespace: molecular_function def: "Interacting selectively with N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine." [GOC:ai, http://cancerweb.ncl.ac.uk/] synonym: "N-acetylgalactosamine lectin" RELATED [] xref: GO:0046871 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0006257 name: metal ion binding namespace: molecular_function def: "Interacting selectively with any metal ion." [GOC:ai] subset: gosubset_prok synonym: "heavy metal binding" NARROW [] synonym: "metal binding" EXACT [] xref: GO:0046872 is_a: CCO:F0005806 ! ion binding [Term] id: CCO:F0006258 name: metal ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of metal ions from one side of a membrane to the other." [GOC:ai] subset: gosubset_prok synonym: "heavy metal ion porter activity" NARROW [] synonym: "heavy metal ion transporter activity" NARROW [] synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] synonym: "heavy metal-exporting ATPase activity" NARROW [] synonym: "high affinity metal ion uptake transporter activity" NARROW [] synonym: "low affinity metal ion uptake transporter activity" NARROW [] xref: GO:0046873 is_a: CCO:F0002557 ! ion transmembrane transporter activity [Term] id: CCO:F0006259 name: ephrin receptor binding namespace: molecular_function def: "Interacting selectively with an ephrin receptor." [GOC:ai] synonym: "Eph receptor binding" EXACT [] synonym: "ephrin" NARROW [] synonym: "GPI-linked ephrin" NARROW [] synonym: "transmembrane ephrin" NARROW [] xref: GO:0046875 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0006260 name: 3,4-didehydroretinal binding namespace: molecular_function def: "Interacting selectively with 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod)." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "blue-sensitive opsin" NARROW [] synonym: "green-sensitive opsin" NARROW [] synonym: "long-wave-sensitive opsin" NARROW [] synonym: "opsin" NARROW [] synonym: "red-sensitive opsin" NARROW [] synonym: "short-wave-sensitive opsin" NARROW [] synonym: "UV-sensitive opsin" NARROW [] synonym: "violet-sensitive opsin" NARROW [] xref: GO:0046876 is_a: CCO:F0001639 ! retinoid binding [Term] id: CCO:F0006261 name: nucleoside triphosphate adenylate kinase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP." [EC:2.7.4.10] synonym: "GTP:AMP phosphotransferase" NARROW [] synonym: "guanosine triphosphate-adenylate kinase" NARROW [] synonym: "isozyme 3 of adenylate kinase activity" EXACT [EC:2.7.4.10] synonym: "nucleoside triphosphate-adenosine monophosphate transphosphorylase activity" EXACT [] synonym: "nucleoside-triphosphate-adenylate kinase activity" EXACT [] synonym: "nucleoside-triphosphate:AMP phosphotransferase activity" EXACT [EC:2.7.4.10] xref: EC:2.7.4.10 xref: GO:0046899 xref: MetaCyc:2.7.4.10-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0006262 name: calcium oxalate binding namespace: molecular_function def: "Interacting selectively with calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] subset: gosubset_prok xref: GO:0046904 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0006263 name: phytoene synthase activity namespace: molecular_function def: "Catalysis of the reaction: prephytoene pyrophosphate = phytoene + pyrophosphate." [GOC:ai, PMID:12641468] comment: Note that this should not be confused with 'geranylgeranyl-diphosphate geranylgeranyltransferase activity ; GO:0016767', EC:2.5.1.32. This activity is the second part of the formation of phytoene from geranylgeranyl-diphosphate, the first stage of which is catalyzed by EC:2.5.1.32. xref: GO:0046905 is_a: CCO:F0000343 ! catalytic activity [Term] id: CCO:F0006264 name: tetrapyrrole binding namespace: molecular_function def: "Interacting selectively with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position." [http://cancerweb.ncl.ac.uk/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok synonym: "porphyrin binding" NARROW [] xref: GO:0046906 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0006265 name: pectinesterase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of any pectinesterase enzyme." [GOC:ai, PMID:10880981] comment: See also the molecular function term 'pectinesterase activity ; GO:0030599'. xref: GO:0046910 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0006266 name: metal chelating activity namespace: molecular_function def: "The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring." [http://cancerweb.ncl.ac.uk/, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0716731363] subset: gosubset_prok synonym: "heavy metal chelation" NARROW [] synonym: "metal chelation" EXACT [] xref: GO:0046911 is_a: CCO:F0006257 ! metal ion binding [Term] id: CCO:F0006267 name: transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer namespace: molecular_function def: "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer." [GOC:jl] subset: gosubset_prok xref: EC:2.3.3 xref: GO:0046912 is_a: CCO:F0003321 ! transferase activity, transferring acyl groups [Term] id: CCO:F0006268 name: transition metal ion binding namespace: molecular_function def: "Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0046914 is_a: CCO:F0005808 ! cation binding is_a: CCO:F0006257 ! metal ion binding [Term] id: CCO:F0006269 name: transition metal ion transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0046915 is_a: CCO:F0006258 ! metal ion transmembrane transporter activity [Term] id: CCO:F0006270 name: triphosphoribosyl-dephospho-CoA synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine." [EC:2.7.8.25] subset: gosubset_prok synonym: "2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase activity" EXACT [EC:2.7.8.25] synonym: "ATP:3-dephospho-CoA 5''-triphosphoribosyltransferase activity" EXACT [EC:2.7.8.25] synonym: "ATP:dephospho-CoA 5-triphosphoribosyl transferase activity" EXACT [] synonym: "CitG activity" RELATED [EC:2.7.8.25] xref: EC:2.7.8.25 xref: GO:0046917 xref: MetaCyc:2.7.8.25-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006271 name: pyruvyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another." [GOC:ai] xref: GO:0046919 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0006272 name: alpha(1,3)-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,3)-linkage." [GOC:ai] xref: EC:2.4.1.- xref: GO:0046920 is_a: CCO:F0001884 ! fucosyltransferase activity [Term] id: CCO:F0006273 name: alpha(1,6)-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,6)-linkage." [GOC:ai] xref: EC:2.4.1.- xref: GO:0046921 is_a: CCO:F0001884 ! fucosyltransferase activity [Term] id: CCO:F0006274 name: peptide-O-fucosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor." [EC:2.4.1.221] synonym: "GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity" EXACT [EC:2.4.1.221] synonym: "GDP-fucose protein O-fucosyltransferase activity" EXACT [EC:2.4.1.221] synonym: "GDP-fucose:polypeptide fucosyltransferase activity" EXACT [EC:2.4.1.221] synonym: "GDP-L-fucose:polypeptide fucosyltransferase activity" EXACT [EC:2.4.1.221] xref: EC:2.4.1.221 xref: GO:0046922 xref: MetaCyc:2.4.1.221-RXN is_a: CCO:F0001884 ! fucosyltransferase activity [Term] id: CCO:F0006275 name: ER retention sequence binding namespace: molecular_function def: "Interacting selectively with an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER." [GOC:ai] synonym: "endoplasmic reticulum retention sequence binding" EXACT [] xref: GO:0046923 is_a: CCO:F0001368 ! signal sequence binding [Term] id: CCO:F0006276 name: sodium-transporting ATP synthase activity, rotational mechanism namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) = ATP + H2O + Na+(in), by a rotational mechanism." [EC:3.6.3.15, TC:3.A.2.1.2] synonym: "sodium-translocating F-type ATPase activity" EXACT [] synonym: "sodium-transporting two-sector ATPase activity" EXACT [] xref: GO:0046932 is_a: CCO:F0002562 ! sodium ion transmembrane transporter activity [Term] id: CCO:F0006277 name: hydrogen ion transporting ATP synthase activity, rotational mechanism namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate = ATP + H2O, coupled with transport of H+ down a concentration gradient, by a rotational mechanism." [EC:3.6.3.14, TC:3.A.2.1.1] subset: gosubset_prok synonym: "H+-transporting ATP synthase activity" EXACT [EC:3.6.3.14] synonym: "hydrogen ion translocating F-type ATPase activity" EXACT [] synonym: "hydrogen ion transporting two-sector ATPase activity" EXACT [] xref: GO:0046933 xref: Reactome:78757 is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity [Term] id: CCO:F0006278 name: phosphatidylinositol-4,5-bisphosphate 3-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate." [EC:2.7.1.153] synonym: "ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity" EXACT [EC:2.7.1.153] synonym: "phosphatidylinositol 3-kinase activity, class I" NARROW [] synonym: "phosphatidylinositol 3-kinase activity, class II" NARROW [] synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" NARROW [] synonym: "type I phosphoinositide 3-kinase activity" NARROW [EC:2.7.1.153] xref: EC:2.7.1.153 xref: GO:0046934 xref: MetaCyc:2.7.1.153-RXN xref: Reactome:78763 is_a: CCO:F0005553 ! phosphoinositide 3-kinase activity [Term] id: CCO:F0006279 name: 1-phosphatidylinositol-3-kinase regulator activity namespace: molecular_function def: "Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity." [GOC:ai] comment: See also the molecular function term '1-phosphatidylinositol-3-kinase activity ; GO:0016303'. synonym: "phosphatidylinositol 3-kinase regulator activity" EXACT [] synonym: "phosphatidylinositol 3-kinase, class I, regulator activity" NARROW [] xref: GO:0046935 is_a: CCO:F0005556 ! phosphoinositide 3-kinase regulator activity [Term] id: CCO:F0006280 name: deoxyadenosine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: deoxyadenosine + H2O = deoxyinosine + NH3." [EC:3.5.4.4, GOC:ai] synonym: "deoxyadenosine deaminase reaction" EXACT [] xref: GO:0046936 is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0006281 name: azetidine-2-carboxylic acid acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid." [PMID:12761200] xref: EC:2.3.1.- xref: GO:0046941 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0006282 name: carboxylic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] subset: gosubset_prok xref: GO:0046943 is_a: CCO:F0001570 ! organic acid transmembrane transporter activity [Term] id: CCO:F0006283 name: hydrogen ion transporting ATPase activity, rotational mechanism namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism." [EC:3.6.3.14] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. subset: gosubset_prok synonym: "ATP phosphohydrolase (H+-transporting) activity" EXACT [EC:3.6.3.14] synonym: "ATP synthase activity" BROAD [EC:3.6.3.14] synonym: "bacterial Ca2+/Mg2+ ATPase" NARROW [EC:3.6.3.14] synonym: "chloroplast ATPase activity" NARROW [EC:3.6.3.14] synonym: "coupling factors (Fo, F1 and CF1)" RELATED [EC:3.6.3.14] synonym: "F(0)F(1)-ATPase activity" NARROW [EC:3.6.3.14] synonym: "F(1)-ATPase activity" NARROW [EC:3.6.3.14] synonym: "F(o)F(1)-ATPase activity" NARROW [EC:3.6.3.14] synonym: "F0F1-ATPase" NARROW [EC:3.6.3.14] synonym: "F1-ATPase" NARROW [EC:3.6.3.14] synonym: "FoF1-ATPase" NARROW [EC:3.6.3.14] synonym: "H(+)-transporting ATP synthase activity" EXACT [EC:3.6.3.14] synonym: "H(+)-transporting ATPase activity" BROAD [EC:3.6.3.14] synonym: "H+-transporting ATPase activity" EXACT [EC:3.6.3.14] synonym: "H+-transporting two-sector ATPase" NARROW [EC:3.6.3.14] synonym: "hydrogen ion translocating A-type ATPase activity" NARROW [] synonym: "hydrogen ion translocating F-type ATPase activity" NARROW [] synonym: "hydrogen ion translocating V-type ATPase activity" NARROW [] synonym: "hydrogen ion transporting two-sector ATPase activity" NARROW [] synonym: "mitochondrial ATPase activity" NARROW [EC:3.6.3.14] synonym: "proton-transporting ATPase activity, rotational mechanism" EXACT [] xref: GO:0046961 is_a: CCO:F0002559 ! hydrogen ion transmembrane transporter activity is_a: CCO:F0004186 ! cation-transporting ATPase activity [Term] id: CCO:F0006284 name: sodium-transporting ATPase activity, rotational mechanism namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out), by a rotational mechanism." [EC:3.6.3.15] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "ATP phosphohydrolase (Na+-transporting) activity" EXACT [EC:3.6.3.15] synonym: "ATP synthase, sodium ion specific activity" EXACT [EC:3.6.3.145] synonym: "Na(+)-translocating ATPase activity" BROAD [EC:3.6.3.15] synonym: "Na(+)-transporting two-sector ATPase activity" EXACT [EC:3.6.3.15] synonym: "Na+-translocating ATPase activity" EXACT [EC:3.6.3.15] synonym: "Na+-translocating F1Fo-ATPase" NARROW [EC:3.6.3.15] synonym: "Na+-transporting two-sector ATPase" NARROW [EC:3.6.3.15] synonym: "sodium transporting ATPase activity, rotational mechanism" EXACT [] synonym: "sodium-translocating F-type ATPase activity" NARROW [] synonym: "sodium-translocating V-type ATPase activity" NARROW [] synonym: "sodium-transporting two-sector ATPase activity" NARROW [] synonym: "vacuolar-type Na+-ATPase" NARROW [EC:3.6.3.15] synonym: "vacuolar-type Na+-translocating ATPase" NARROW [EC:3.6.3.15] xref: GO:0046962 is_a: CCO:F0002562 ! sodium ion transmembrane transporter activity is_a: CCO:F0004186 ! cation-transporting ATPase activity [Term] id: CCO:F0006285 name: 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfatefrom one side of a membrane to the other." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "3'-phosphoadenosine 5'-phosphosulphate transporter activity" EXACT [] synonym: "adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity" EXACT [] synonym: "PAPS transporter activity" EXACT [] xref: GO:0046964 is_a: CCO:F0002682 ! purine nucleoside transmembrane transporter activity [Term] id: CCO:F0006286 name: retinoid X receptor binding namespace: molecular_function def: "Interacting selectively with a retinoid X receptor." [GOC:ai] synonym: "RXR binding" EXACT [] xref: GO:0046965 is_a: CCO:F0005774 ! retinoic acid receptor binding [Term] id: CCO:F0006287 name: thyroid hormone receptor binding namespace: molecular_function def: "Interacting selectively with a thyroid hormone receptor." [GOC:ai] synonym: "ligand-dependent thyroid hormone receptor interactor activity" NARROW [] xref: GO:0046966 is_a: CCO:F0001738 ! transcription factor binding is_a: CCO:F0005585 ! nuclear hormone receptor binding [Term] id: CCO:F0006288 name: NAD-dependent histone deacetylase activity (H3-K9 specific) namespace: molecular_function def: "Catalysis of the NAD-dependent removal of an acetyl group from lysine at position 9 of the histone H3 protein." [GOC:ai] xref: GO:0046969 is_a: CCO:F0003591 ! NAD-dependent histone deacetylase activity is_a: CCO:F0004947 ! histone deacetylase activity (H3-K9 specific) [Term] id: CCO:F0006289 name: NAD-dependent histone deacetylase activity (H4-K16 specific) namespace: molecular_function def: "Catalysis of the removal of an acetyl group from lysine at position 16 of the histone H4 protein." [GOC:ai] xref: GO:0046970 is_a: CCO:F0003591 ! NAD-dependent histone deacetylase activity [Term] id: CCO:F0006290 name: histone acetyltransferase activity (H4-K16 specific) namespace: molecular_function def: "Catalysis of the addition of an acetyl group onto lysine at position 16 of the histone H4 protein." [GOC:ai] synonym: "histone lysine acetyltransferase activity (H4-K16 specific)" EXACT [] xref: GO:0046972 is_a: CCO:F0000813 ! histone acetyltransferase activity [Term] id: CCO:F0006291 name: histone lysine N-methyltransferase activity (H3-K9 specific) namespace: molecular_function def: "Catalysis of the addition of a methyl group onto lysine at position 9 of the histone H3 protein." [GOC:ai] xref: GO:0046974 is_a: CCO:F0003617 ! histone-lysine N-methyltransferase activity [Term] id: CCO:F0006292 name: histone lysine N-methyltransferase activity (H3-K36 specific) namespace: molecular_function def: "Catalysis of the addition of a methyl group onto lysine at position 36 of the histone H3 protein." [GOC:ai] xref: GO:0046975 is_a: CCO:F0003617 ! histone-lysine N-methyltransferase activity [Term] id: CCO:F0006293 name: histone lysine N-methyltransferase activity (H3-K27 specific) namespace: molecular_function def: "Catalysis of the addition of a methyl group onto lysine at position 27 of the histone H3 protein." [GOC:ai] xref: GO:0046976 is_a: CCO:F0003617 ! histone-lysine N-methyltransferase activity [Term] id: CCO:F0006294 name: TAP binding namespace: molecular_function def: "Interacting selectively with TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2." [PMID:11133832] xref: GO:0046977 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006295 name: TAP1 binding namespace: molecular_function def: "Interacting selectively with the TAP1 subunit of TAP (transporter associated with antigen processing) protein." [PMID:11133832] xref: GO:0046978 is_a: CCO:F0006294 ! TAP binding [Term] id: CCO:F0006296 name: TAP2 binding namespace: molecular_function def: "Interacting selectively with the TAP2 subunit of TAP (transporter associated with antigen processing) protein." [PMID:11133832] xref: GO:0046979 is_a: CCO:F0006294 ! TAP binding [Term] id: CCO:F0006297 name: tapasin binding namespace: molecular_function def: "Interacting selectively with tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules." [PMID:12594855] xref: GO:0046980 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006298 name: beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids." [GOC:bf, PMID:12130631, PMID:12130651] synonym: "UDP-N-acetylglucosamine:beta-D-mannosyl-glycolipid beta-1,3-N-acetylglucosaminyltransferase activity" EXACT [] xref: GO:0046981 is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006299 name: protein heterodimerization activity namespace: molecular_function def: "Interacting selectively with a nonidentical protein to form a heterodimer." [GOC:ai] xref: GO:0046982 is_a: CCO:F0006300 ! protein dimerization activity [Term] id: CCO:F0006300 name: protein dimerization activity namespace: molecular_function def: "The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0046983 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006301 name: N-acetyllactosamine beta-1,3-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine)." [GOC:bf, PMID:12511570] synonym: "galactosyl beta-1,4 N-acetylglucosamine beta-1,3 glucuronosyltransferase activity" EXACT [] xref: GO:0046987 is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0006302 name: asioloorosomucoid beta-1,3-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid." [GOC:bf, PMID:12511570] xref: GO:0046988 is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0006303 name: galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids." [GOC:bf, PMID:12511570] xref: GO:0046989 is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0006304 name: N-hydroxyarylamine O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine." [EC:2.3.1.118, MetaCyc:2.3.1.118-RXN] subset: gosubset_prok synonym: "acetyl-CoA:N-hydroxyarylamine O-acetyltransferase activity" EXACT [EC:2.3.1.118] synonym: "arylhydroxamate N,O-acetyltransferase activity" EXACT [EC:2.3.1.118] synonym: "N-hydroxy-2-aminofluorene-O-acetyltransferase activity" EXACT [EC:2.3.1.118] xref: EC:2.3.1.118 xref: GO:0046990 xref: MetaCyc:2.3.1.118-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0006305 name: hydroxynitrilase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxyisobutyronitrile = cyanide + acetone." [EC:4.1.2.39, MetaCyc:4.1.2.39-RXN] synonym: "(S)-acetone-cyanohydrin lyase activity" EXACT [EC:4.1.2.39] synonym: "2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)" EXACT [EC:4.1.2.39] synonym: "2-hydroxyisobutyronitrile acetone-lyase activity" EXACT [EC:4.1.2.39] synonym: "hydroxynitrile lyase activity" BROAD [] synonym: "oxynitrilase activity" BROAD [EC:4.1.2.39] xref: EC:4.1.2.39 xref: GO:0046991 xref: MetaCyc:4.1.2.39-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006306 name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y." [GOC:ai] comment: Note that enzymes of class EC:1.21.99.- should also be annotated to this term. subset: gosubset_prok synonym: "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors" NARROW [] xref: EC:1.21 xref: GO:0046992 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006307 name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen." [GOC:ai] subset: gosubset_prok xref: EC:1.21.3 xref: GO:0046993 is_a: CCO:F0006306 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond [Term] id: CCO:F0006308 name: oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound." [GOC:jl] subset: gosubset_prok xref: EC:1.12.5 xref: GO:0046994 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0006309 name: oxidoreductase activity, acting on hydrogen as donor, with other known acceptors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound." [GOC:ai] subset: gosubset_prok xref: EC:1.12.98 xref: GO:0046995 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0006310 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated." [GOC:mah] xref: EC:1.14.21 xref: GO:0046996 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0006311 name: oxidoreductase activity, acting on the CH-NH group of donors, with a flavin as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin." [GOC:jl] subset: gosubset_prok xref: EC:1.5.8 xref: GO:0046997 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0006313 name: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 2-dehydro-3-deoxy-D-gluconate = NADPH + H+ + (4S,5S)-4,5-dehydroxy-2,6-dioxohexanoate." [EC:1.1.1.126, MetaCyc:1.1.1.126-RXN] synonym: "2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase activity" EXACT [EC:1.1.1.126] synonym: "2-keto-3-deoxy-D-gluconate dehydrogenase activity" EXACT [EC:1.1.1.126] xref: EC:1.1.1.126 xref: GO:0047000 xref: MetaCyc:1.1.1.126-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006314 name: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate." [EC:1.1.1.127, MetaCyc:1.1.1.127-RXN] synonym: "2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase activity" EXACT [EC:1.1.1.127] synonym: "2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase activity" EXACT [EC:1.1.1.127] synonym: "2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity" EXACT [EC:1.1.1.127] synonym: "2-keto-3-deoxygluconate 5-dehydrogenase activity" EXACT [EC:1.1.1.127] synonym: "2-keto-3-deoxygluconate dehydrogenase activity" EXACT [EC:1.1.1.127] xref: EC:1.1.1.127 xref: GO:0047001 xref: MetaCyc:1.1.1.127-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006315 name: L-arabinitol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + L-arabitol = NADH + H+ + L-ribulose." [EC:1.1.1.13, MetaCyc:1.1.1.13-RXN] synonym: "L-arabinitol 2-dehydrogenase (ribulose forming) activity" EXACT [] xref: EC:1.1.1.13 xref: GO:0047002 xref: MetaCyc:1.1.1.13-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006316 name: dTDP-6-deoxy-L-talose 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + dTDP-6-deoxy-L-talose = NADPH + dTDP-4-dehydro-6-deoxy-L-mannose." [EC:1.1.1.134, MetaCyc:1.1.1.134-RXN] synonym: "dTDP-6-deoxy-L-talose dehydrogenase (4-reductase)" EXACT [EC:1.1.1.134] synonym: "dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.134] synonym: "TDP-6-deoxy-L-talose dehydrogenase activity" EXACT [EC:1.1.1.134] synonym: "thymidine diphospho-6-deoxy-L-talose dehydrogenase activity" EXACT [EC:1.1.1.134] xref: EC:1.1.1.134 xref: GO:0047003 xref: MetaCyc:1.1.1.134-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006317 name: UDP-N-acetylglucosamine 6-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 2 NAD+ + UDP-N-acetyl-D-glucosamine = 2 NADH + 2 H+ + UDP-N-acetyl-2-amino-d-glucuronate." [EC:1.1.1.136, MetaCyc:1.1.1.136-RXN] synonym: "UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase activity" EXACT [EC:1.1.1.136] synonym: "UDP-GLcNAc dehydrogenase activity" EXACT [EC:1.1.1.136] synonym: "UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase activity" EXACT [EC:1.1.1.136] synonym: "UDPacetylglucosamine dehydrogenase activity" EXACT [EC:1.1.1.136] synonym: "uridine diphosphoacetylglucosamine dehydrogenase activity" EXACT [EC:1.1.1.136] xref: EC:1.1.1.136 xref: GO:0047004 xref: MetaCyc:1.1.1.136-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006318 name: 16-alpha-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid." [EC:1.1.1.147, MetaCyc:1.1.1.147-RXN] synonym: "16alpha-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.147] synonym: "16alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.147] synonym: "16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase activity" EXACT [EC:1.1.1.147] xref: EC:1.1.1.147 xref: GO:0047005 xref: MetaCyc:1.1.1.147-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006319 name: 20-alpha-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone." [EC:1.1.1.149, MetaCyc:1.1.1.149-RXN] subset: gosubset_prok synonym: "20alpha-HSD" RELATED [EC:1.1.1.149] synonym: "20alpha-HSDH" RELATED [EC:1.1.1.149] synonym: "20alpha-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.149] synonym: "20alpha-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.149] synonym: "20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity" EXACT [EC:1.1.1.149] xref: EC:1.1.1.149 xref: GO:0047006 xref: MetaCyc:1.1.1.149-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006320 name: 21-hydroxysteroid dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + pregnan-21-ol = NADH + H+ + pregnan-21-al." [EC:1.1.1.150, MetaCyc:1.1.1.150-RXN] synonym: "21-hydroxysteroid:NAD+ 21-oxidoreductase activity" EXACT [EC:1.1.1.150] xref: EC:1.1.1.150 xref: GO:0047007 xref: MetaCyc:1.1.1.150-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006321 name: 21-hydroxysteroid dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + pregnan-21-ol = NADPH + H+ + pregnan-21-al." [EC:1.1.1.151, MetaCyc:1.1.1.151-RXN] synonym: "21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.151] synonym: "21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity" EXACT [EC:1.1.1.151] synonym: "21-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.151] synonym: "21-hydroxysteroid:NADP+ 21-oxidoreductase activity" EXACT [EC:1.1.1.151] synonym: "NADP-21-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.151] xref: EC:1.1.1.151 xref: GO:0047008 xref: MetaCyc:1.1.1.151-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006322 name: 3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione." [EC:1.1.1.152, MetaCyc:1.1.1.152-RXN] synonym: "3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase activity" EXACT [EC:1.1.1.152] synonym: "3alpha-hydroxy-5beta-steroid dehydrogenase activity" EXACT [EC:1.1.1.152] synonym: "3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.152] synonym: "etiocholanolone 3-alpha-dehydrogenase activity" EXACT [EC:1.1.1.152] synonym: "etiocholanolone 3alpha-dehydrogenase activity" EXACT [EC:1.1.1.152] xref: EC:1.1.1.152 xref: GO:0047009 xref: MetaCyc:1.1.1.152-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006323 name: hydroxycyclohexanecarboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate = NADH + H+ + (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate." [EC:1.1.1.166, MetaCyc:1.1.1.166-RXN] synonym: "(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity" EXACT [EC:1.1.1.166] synonym: "(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.166] synonym: "dihydroxycyclohexanecarboxylate dehydrogenase activity" EXACT [EC:1.1.1.166] xref: EC:1.1.1.166 xref: GO:0047010 xref: MetaCyc:1.1.1.166-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006324 name: 2-dehydropantolactone reductase (A-specific) activity namespace: molecular_function def: "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+." [EC:1.1.1.168, MetaCyc:1.1.1.168-RXN] synonym: "(R)-pantolactone:NADP+ oxidoreductase (A-specific)" EXACT [EC:1.1.1.168] synonym: "2-dehydropantoyl-lactone reductase (A-specific) activity" EXACT [EC:1.1.1.168] synonym: "2-ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.168] synonym: "2-oxopantoyl lactone reductase" BROAD [EC:1.1.1.168] synonym: "ketopantoyl lactone reductase activity" BROAD [EC:1.1.1.168] xref: EC:1.1.1.168 xref: GO:0047011 xref: MetaCyc:1.1.1.168-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006325 name: sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one." [EC:1.1.1.170, MetaCyc:1.1.1.170-RXN] synonym: "3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity" EXACT [] synonym: "3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity" RELATED [EC:1.1.1.170] synonym: "3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase activity" RELATED [EC:1.1.1.170] synonym: "3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [EC:1.1.1.170] synonym: "sterol 4-alpha-carboxylic decarboxylase activity" RELATED [EC:1.1.1.170] xref: EC:1.1.1.170 xref: GO:0047012 xref: MetaCyc:1.1.1.170-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006326 name: 12-alpha-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate = NADPH + H+ + 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate." [EC:1.1.1.176, MetaCyc:1.1.1.176-RXN] subset: gosubset_prok synonym: "12alpha-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.176] synonym: "12alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.176] synonym: "12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity" EXACT [EC:1.1.1.176] synonym: "NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.176] synonym: "NADP-12alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.176] xref: EC:1.1.1.176 xref: GO:0047013 xref: MetaCyc:1.1.1.176-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006327 name: glycerol-3-phosphate 1-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + glycerol-3-phosphate = NADPH + H+ + glyceraldehyde-3-phosphate." [EC:1.1.1.177, MetaCyc:1.1.1.177-RXN] synonym: "glycerin-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.177] synonym: "glycerol phosphate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.177] synonym: "L-glycerol 3-phosphate:NADP oxidoreductase activity" EXACT [EC:1.1.1.177] synonym: "NADPH-dependent glycerin-3-phosphate dehydrogenase activity" EXACT [EC:1.1.1.177] synonym: "sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.177] xref: EC:1.1.1.177 xref: GO:0047014 xref: MetaCyc:1.1.1.177-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006328 name: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA." [EC:1.1.1.178, MetaCyc:1.1.1.178-RXN] synonym: "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.178] synonym: "2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity" EXACT [EC:1.1.1.178] synonym: "2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity" EXACT [EC:1.1.1.178] synonym: "2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity" EXACT [EC:1.1.1.178] xref: EC:1.1.1.178 xref: GO:0047015 xref: MetaCyc:1.1.1.178-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006329 name: cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one." [EC:1.1.1.181, MetaCyc:1.1.1.181-RXN] synonym: "3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity" EXACT [EC:1.1.1.181] synonym: "3beta-hydroxy-delta5-C27-steroid oxidoreductase" BROAD [EC:1.1.1.181] synonym: "cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity" EXACT [EC:1.1.1.181] synonym: "cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.181] xref: EC:1.1.1.181 xref: GO:0047016 xref: MetaCyc:1.1.1.181-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006330 name: prostaglandin-F synthase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate." [EC:1.1.1.188, MetaCyc:1.1.1.188-RXN] synonym: "(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity" EXACT [EC:1.1.1.188] synonym: "NADPH-dependent prostaglandin D2 11-keto reductase activity" EXACT [EC:1.1.1.188] synonym: "PGD(2) 11-ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "PGD2 11-ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "PGF synthetase activity" EXACT [EC:1.1.1.188] synonym: "PGF2alpha synthetase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin 11-keto reductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin 11-ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin D2-ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin F synthase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin F synthetase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin-D(2) 11-ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin-D(2) 11-reductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin-D(2) ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin-D2 11-ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin-D2 11-reductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin-D2 ketoreductase activity" EXACT [EC:1.1.1.188] synonym: "prostaglandin-F synthetase activity" EXACT [EC:1.1.1.188] synonym: "reductase, 15-hydroxy-11-oxoprostaglandin" EXACT [EC:1.1.1.188] synonym: "synthetase, prostaglandin F2alpha" EXACT [EC:1.1.1.188] xref: EC:1.1.1.188 xref: GO:0047017 xref: MetaCyc:1.1.1.188-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006331 name: indole-3-acetaldehyde reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + indole-3-ethanol = NADH + H+ + indole acetaldehyde." [EC:1.1.1.190, MetaCyc:1.1.1.190-RXN] synonym: "(indol-3-yl)ethanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.190] synonym: "indole-3-ethanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.190] synonym: "indoleacetaldehyde reductase activity" EXACT [EC:1.1.1.190] xref: EC:1.1.1.190 xref: GO:0047018 xref: MetaCyc:1.1.1.190-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006332 name: indole-3-acetaldehyde reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + indole-3-ethanol = NADPH + H+ + indole acetaldehyde." [EC:1.1.1.191, MetaCyc:1.1.1.191-RXN] synonym: "(indol-3-yl)ethanol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.191] synonym: "indole-3-ethanol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.191] synonym: "indoleacetaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.1.1.191] xref: EC:1.1.1.191 xref: GO:0047019 xref: MetaCyc:1.1.1.191-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006333 name: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate." [EC:1.1.1.196, MetaCyc:1.1.1.196-RXN] synonym: "(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity" EXACT [EC:1.1.1.196] synonym: "15-hydroxy PGD2 dehydrogenase activity" EXACT [EC:1.1.1.196] synonym: "15-hydroxyprostaglandin dehydrogenase (NADP)" EXACT [EC:1.1.1.196] synonym: "dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.196] synonym: "dehydrogenase, prostaglandin D2" EXACT [EC:1.1.1.196] synonym: "NADP-dependent 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.196] synonym: "NADP-linked 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.196] synonym: "NADP-linked prostaglandin D2 dehydrogenase activity" EXACT [EC:1.1.1.196] synonym: "NADP-PGD2 dehydrogenase activity" EXACT [EC:1.1.1.196] synonym: "NADP-specific 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.196] synonym: "prostaglandin D2 dehydrogenase activity" EXACT [EC:1.1.1.196] synonym: "prostaglandin-D 15-dehydrogenase (NADP(+)) activity" EXACT [EC:1.1.1.196] synonym: "prostaglandin-D 15-dehydrogenase (NADP)" EXACT [EC:1.1.1.196] synonym: "prostaglandin-D 15-dehydrogenase (NADP+) activity" EXACT [EC:1.1.1.196] xref: EC:1.1.1.196 xref: GO:0047020 xref: MetaCyc:1.1.1.196-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006334 name: 15-hydroxyprostaglandin dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate = NADPH + H+ + (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate." [EC:1.1.1.197, MetaCyc:1.1.1.197-RXN] synonym: "(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity" EXACT [EC:1.1.1.197] synonym: "NADP-dependent 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.197] synonym: "NADP-linked 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.197] synonym: "NADP-specific 15-hydroxyprostaglandin dehydrogenase" BROAD [EC:1.1.1.197] synonym: "type II 15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.197] xref: EC:1.1.1.197 xref: GO:0047021 xref: MetaCyc:1.1.1.197-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006335 name: 7-beta-hydroxysteroid dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 7-beta-hydroxysteroid = NADPH + H+ + 7-oxosteroid." [EC:1.1.1.201, MetaCyc:1.1.1.201-RXN] synonym: "7beta-hydroxysteroid dehydrogenase (NADP+)" EXACT [EC:1.1.1.201] synonym: "7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity" EXACT [EC:1.1.1.201] synonym: "NADP-dependent 7-beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.201] synonym: "NADP-dependent 7beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.201] xref: EC:1.1.1.201 xref: GO:0047022 xref: MetaCyc:1.1.1.201-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006336 name: 3(or 17)-alpha-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione." [EC:1.1.1.209, MetaCyc:1.1.1.209-RXN] synonym: "3(17)alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.209] synonym: "3(or 17)alpha-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.209] synonym: "3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.209] xref: EC:1.1.1.209 xref: GO:0047023 xref: MetaCyc:1.1.1.209-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006337 name: 3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 5-alpha-androstan-3-beta,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADPH + H+." [EC:1.1.1.210, MetaCyc:1.1.1.210-RXN] synonym: "3-beta-HSD activity" EXACT [EC:1.1.1.210] synonym: "3beta(or 20alpha)-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.210] synonym: "3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.210] synonym: "3beta,20alpha-hydroxysteroid oxidoreductase activity" EXACT [EC:1.1.1.210] synonym: "dehydrogenase, 3beta,20alpha-hydroxy steroid" EXACT [EC:1.1.1.210] synonym: "progesterone reductase activity" BROAD [EC:1.1.1.210] xref: EC:1.1.1.210 xref: GO:0047024 xref: MetaCyc:1.1.1.210-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006338 name: 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein]." [EC:1.1.1.212, MetaCyc:1.1.1.212-RXN] synonym: "(3R)-3-hydroxyacyl-acyl-carrier-protein:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.212] synonym: "3-oxoacyl-[acyl-carrier protein] reductase (NADH) activity" EXACT [] synonym: "3-oxoacyl-ACP reductase (NADH) activity" EXACT [] synonym: "3-oxoacyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide) reductase activity" EXACT [EC:1.1.1.212] synonym: "3-oxoacyl-acyl-carrier-protein reductase (NADH)" EXACT [EC:1.1.1.212] xref: EC:1.1.1.212 xref: GO:0047025 xref: MetaCyc:1.1.1.212-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006339 name: 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+." [EC:1.1.1.213, MetaCyc:1.1.1.213-RXN] synonym: "3alpha-hydroxysteroid dehydrogenase (A-specific)" EXACT [EC:1.1.1.213] synonym: "3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)" EXACT [EC:1.1.1.213] xref: EC:1.1.1.213 xref: GO:0047026 xref: MetaCyc:1.1.1.213-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006340 name: benzyl-2-methyl-hydroxybutyrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + benzyl (2R,3S)-2-methyl-3-hydroxybutanoate = NADPH + H+ + benzyl 2-methyl-3-oxobutanoate." [EC:1.1.1.217, MetaCyc:1.1.1.217-RXN] synonym: "benzyl 2-methyl-3-hydroxybutyrate dehydrogenase activity" EXACT [EC:1.1.1.217] synonym: "benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.217] xref: EC:1.1.1.217 xref: GO:0047027 xref: MetaCyc:1.1.1.217-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006341 name: 6-pyruvoyltetrahydropterin 2'-reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin." [EC:1.1.1.220, MetaCyc:1.1.1.220-RXN] subset: gosubset_prok synonym: "6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.1.1.220] synonym: "6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity" EXACT [EC:1.1.1.220] synonym: "6-pyruvoyl-tetrahydropterin 2'-reductase activity" EXACT [EC:1.1.1.220] synonym: "6-pyruvoyltetrahydropterin reductase activity" EXACT [EC:1.1.1.220] synonym: "6PPH4(2'-oxo) reductase activity" EXACT [EC:1.1.1.220] synonym: "pyruvoyl-tetrahydropterin reductase activity" EXACT [EC:1.1.1.220] xref: EC:1.1.1.220 xref: GO:0047028 xref: MetaCyc:1.1.1.220-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006343 name: 4-hydroxycyclohexanecarboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 4-hydroxycyclohexanecarboxylate = NADH + H+ + 4-oxocyclohexanecarboxylate." [EC:1.1.1.226, MetaCyc:1.1.1.226-RXN] synonym: "trans-4-hydroxycyclohexanecarboxylate dehydrogenase activity" EXACT [EC:1.1.1.226] synonym: "trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.226] xref: EC:1.1.1.226 xref: GO:0047030 xref: MetaCyc:1.1.1.226-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006344 name: diethyl 2-methyl-3-oxosuccinate reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + diethyl (2R,3R)-2-methyl-3-hydroxysuccinate = NADPH + H+ + diethyl-2-methyl-3-oxosuccinate." [EC:1.1.1.229, MetaCyc:1.1.1.229-RXN] synonym: "diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.229] xref: EC:1.1.1.229 xref: GO:0047031 xref: MetaCyc:1.1.1.229-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006345 name: 3-alpha-hydroxyglycyrrhetinate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 3-alpha-hydroxyglycyrrhetinate = NADPH + H+ + 3-oxoglycyrrhetinate." [EC:1.1.1.230, MetaCyc:1.1.1.230-RXN] synonym: "3alpha-hydroxyglycyrrhetinate dehydrogenase activity" EXACT [EC:1.1.1.230] synonym: "3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.230] xref: EC:1.1.1.230 xref: GO:0047032 xref: MetaCyc:1.1.1.230-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006346 name: 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-dienoate." [EC:1.1.1.231, MetaCyc:1.1.1.231-RXN] synonym: "(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity" EXACT [EC:1.1.1.231] synonym: "NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity" EXACT [EC:1.1.1.231] synonym: "NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity" EXACT [EC:1.1.1.231] synonym: "PG I2 dehydrogenase activity" EXACT [EC:1.1.1.231] synonym: "prostacyclin dehydrogenase activity" EXACT [EC:1.1.1.231] xref: EC:1.1.1.231 xref: GO:0047033 xref: MetaCyc:1.1.1.231-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006347 name: 15-hydroxyicosatetraenoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate." [EC:1.1.1.232, MetaCyc:1.1.1.232-RXN] synonym: "(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase activity" EXACT [EC:1.1.1.232] synonym: "15-hydroxyeicosatetraenoate dehydrogenase activity" EXACT [EC:1.1.1.232] xref: EC:1.1.1.232 xref: GO:0047034 xref: MetaCyc:1.1.1.232-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006348 name: 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + testosterone = NADH + H+ + androst-4-ene-3,17-dione." [EC:1.1.1.239, MetaCyc:1.1.1.239-RXN] synonym: "3alpha(17beta)-HSD" RELATED [EC:1.1.1.239] synonym: "3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)" EXACT [EC:1.1.1.239] synonym: "3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.239] synonym: "3alpha,17beta-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.239] xref: EC:1.1.1.239 xref: GO:0047035 xref: MetaCyc:1.1.1.239-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006349 name: codeinone reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + codeine = NADPH + H+ + codeinone." [EC:1.1.1.247, MetaCyc:1.1.1.247-RXN] synonym: "codeine:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.247] xref: EC:1.1.1.247 xref: GO:0047036 xref: MetaCyc:1.1.1.247-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006350 name: salutaridine reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + salutaridinol = NADPH + H+ + salutaridine." [EC:1.1.1.248, MetaCyc:1.1.1.248-RXN] synonym: "salutaridinol:NADP+ 7-oxidoreductase activity" EXACT [EC:1.1.1.248] xref: EC:1.1.1.248 xref: GO:0047037 xref: MetaCyc:1.1.1.248-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006351 name: D-arabinitol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + D-arabitol = NADH + H+ + D-ribulose." [EC:1.1.1.250, MetaCyc:1.1.1.250-RXN] synonym: "D-arabinitol 2-dehydrogenase (ribulose-forming) activity" EXACT [EC:1.1.1.250] synonym: "D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)" EXACT [EC:1.1.1.250] xref: EC:1.1.1.250 xref: GO:0047038 xref: MetaCyc:1.1.1.250-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006352 name: tetrahydroxynaphthalene reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol." [EC:1.1.1.252, MetaCyc:1.1.1.252-RXN] synonym: "scytalone:NADP+ delta5-oxidoreductase activity" EXACT [EC:1.1.1.252] synonym: "T4HN reductase activity" EXACT [EC:1.1.1.252] xref: EC:1.1.1.252 xref: GO:0047039 xref: MetaCyc:1.1.1.252-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006353 name: pteridine reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 NADP+ + tetra-hydro-biopterin = 2 NADPH + 2 H+ + biopterin." [EC:1.1.1.253, MetaCyc:1.1.1.253-RXN] comment: Note that this function was formerly EC:1.1.1.253. synonym: "5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.33] synonym: "dihydrobiopterin reduction" RELATED [] synonym: "pteridine reductase 1 activity" NARROW [EC:1.5.1.33e] synonym: "PTR1" RELATED [EC:1.5.1.33] synonym: "ptr1 activity" NARROW [EC:1.5.1.33e] xref: EC:1.5.1.33 xref: GO:0047040 xref: MetaCyc:1.1.1.253-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006355 name: 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+." [EC:1.1.1.50, MetaCyc:1.1.1.50-RXN] subset: gosubset_prok synonym: "3-alpha-HSD activity" EXACT [EC:1.1.1.50] synonym: "3alpha-HSD" RELATED [EC:1.1.1.50] synonym: "3alpha-hydroxysteroid dehydrogenase (B-specific)" EXACT [EC:1.1.1.50] synonym: "3alpha-hydroxysteroid oxidoreductase activity" EXACT [EC:1.1.1.50] synonym: "3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)" EXACT [EC:1.1.1.50] synonym: "hydroxyprostaglandin dehydrogenase activity" RELATED [EC:1.1.1.50] synonym: "sterognost 3alpha" RELATED [EC:1.1.1.50] xref: EC:1.1.1.50 xref: GO:0047042 xref: MetaCyc:1.1.1.50-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006356 name: 3-alpha-hydroxycholanate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-cholanate = NADH + H+ + 3-oxo-5-beta-cholanate." [EC:1.1.1.52, MetaCyc:1.1.1.52-RXN] synonym: "3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.52] synonym: "3alpha-hydroxycholanate dehydrogenase activity" EXACT [EC:1.1.1.52] synonym: "alpha-hydroxy-cholanate dehydrogenase activity" EXACT [EC:1.1.1.52] xref: EC:1.1.1.52 xref: GO:0047043 xref: MetaCyc:1.1.1.52-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006357 name: 3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+." [EC:1.1.1.53, MetaCyc:1.1.1.53-RXN] subset: gosubset_prok synonym: "(R)-20-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.53] synonym: "20beta-HSD" RELATED [EC:1.1.1.53] synonym: "20beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.53] synonym: "3alpha(or 20beta)-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.53] synonym: "3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.53] synonym: "3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity" EXACT [EC:1.1.1.53] synonym: "cortisone reductase activity" EXACT [EC:1.1.1.53] synonym: "dehydrogenase, 20beta-hydroxy steroid" EXACT [EC:1.1.1.53] synonym: "delta4-3-ketosteroid hydrogenase activity" EXACT [EC:1.1.1.53] synonym: "NADH-20beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.53] xref: EC:1.1.1.53 xref: GO:0047044 xref: MetaCyc:1.1.1.53-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006358 name: testosterone 17-beta-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione." [EC:1.1.1.64, MetaCyc:1.1.1.64-RXN] synonym: "17-ketoreductase activity" BROAD [EC:1.1.1.64] synonym: "17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity" EXACT [EC:1.1.1.64] synonym: "NADP-dependent testosterone-17beta-oxidoreductase activity" EXACT [EC:1.1.1.64] synonym: "testosterone 17beta-dehydrogenase (NADP+)" EXACT [EC:1.1.1.64] xref: EC:1.1.1.64 xref: GO:0047045 xref: MetaCyc:1.1.1.64-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006359 name: homoisocitrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate." [EC:1.1.1.155, EC:1.1.1.87, MetaCyc:1.1.1.87-RXN] comment: Note that EC:1.1.1.155 was merged into EC:1.1.1.87 as they are identical. synonym: "(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity" EXACT [EC:1.1.1.87] synonym: "(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.87] synonym: "(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.87] synonym: "2-hydroxy-3-carboxyadipate dehydrogenase activity" EXACT [EC:1.1.1.87] synonym: "3-carboxy-2-hydroxyadipate dehydrogenase activity" EXACT [] synonym: "3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity" EXACT [EC:1.1.1.87] synonym: "3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.87] synonym: "homoisocitric dehydrogenase activity" EXACT [EC:1.1.1.87] xref: EC:1.1.1.87 xref: GO:0047046 xref: GO:0047984 xref: MetaCyc:1.1.1.87-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006360 name: oxaloglycolate reductase (decarboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate." [EC:1.1.1.92, MetaCyc:1.1.1.92-RXN] synonym: "D-glycerate:NAD(P)+ oxidoreductase (carboxylating)" EXACT [EC:1.1.1.92] xref: EC:1.1.1.92 xref: GO:0047047 xref: MetaCyc:1.1.1.92-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006361 name: 3-hydroxybenzyl-alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 3-hydroxybenzyl alcohol = NADPH + H+ + 3-hydroxybenzaldehyde." [EC:1.1.1.97, MetaCyc:1.1.1.97-RXN] synonym: "3-hydroxybenzyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.97] synonym: "m-hydroxybenzyl alcohol (NADP) dehydrogenase activity" EXACT [EC:1.1.1.97] synonym: "m-hydroxybenzyl alcohol dehydrogenase activity" EXACT [EC:1.1.1.97] synonym: "m-hydroxybenzylalcohol dehydrogenase activity" EXACT [EC:1.1.1.97] xref: EC:1.1.1.97 xref: GO:0047048 xref: MetaCyc:1.1.1.97-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006364 name: D-lactate dehydrogenase (cytochrome c-553) activity namespace: molecular_function def: "Catalysis of the reaction: 2 ferricytochrome C-553 + D-lactate = 2 ferrocytochrome C-553 + pyruvate." [EC:1.1.2.5, MetaCyc:1.1.2.5-RXN] synonym: "(R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity" EXACT [EC:1.1.2.5] xref: EC:1.1.2.5 xref: GO:0047051 xref: MetaCyc:1.1.2.5-RXN is_a: CCO:F0003456 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor [Term] id: CCO:F0006367 name: berbamunine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + R-N-methylcoclaurine + S-N-methylcoclaurine = 2 H2O + NADP+ + berbamunine." [EC:1.14.21.3, MetaCyc:1.1.3.34-RXN] synonym: "(S)-N-methylcoclaurine oxidase (C-O phenol-coupling) activity" EXACT [EC:1.14.21.3] synonym: "(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (C-O phenol-coupling)" EXACT [EC:1.14.21.3] xref: EC:1.14.21.3 xref: GO:0047054 xref: MetaCyc:1.1.3.34-RXN is_a: CCO:F0006310 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated [Term] id: CCO:F0006368 name: salutaridine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + (R)-reticuline = 2 H2O + NADP+ + salutaridine." [EC:1.14.21.4, MetaCyc:1.1.3.35-RXN] synonym: "(R)-reticuline oxidase (C-C phenol-coupling) activity" EXACT [EC:1.14.21.4] synonym: "(R)-reticuline,NADPH:oxygen oxidoreductase (C-C phenol-coupling)" EXACT [EC:1.14.21.4] xref: EC:1.14.21.4 xref: GO:0047055 xref: MetaCyc:1.1.3.35-RXN is_a: CCO:F0006310 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated [Term] id: CCO:F0006370 name: vitamin-K-epoxide reductase (warfarin-sensitive) activity namespace: molecular_function def: "Catalysis of the reaction: 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol." [EC:1.1.4.1, MetaCyc:1.1.4.1-RXN] synonym: "2-methyl-3-phytyl-1,4-naphthoquinone:oxidized-dithiothreitol oxidoreductase activity" EXACT [EC:1.1.4.1] synonym: "phylloquinone epoxide reductase activity" EXACT [EC:1.1.4.1] synonym: "vitamin K1 epoxide reductase activity" NARROW [EC:1.1.4.1] xref: EC:1.1.4.1 xref: GO:0047057 xref: MetaCyc:1.1.4.1-RXN xref: Reactome:82285 is_a: CCO:F0003458 ! oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor [Term] id: CCO:F0006371 name: vitamin-K-epoxide reductase (warfarin-insensitive) activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol." [EC:1.1.4.2, MetaCyc:1.1.4.2-RXN] synonym: "3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone:oxidized-dithiothreitol oxidoreductase activity" EXACT [EC:1.1.4.2] synonym: "vitamin K 2,3-epoxide reductase activity" EXACT [EC:1.1.4.2] xref: EC:1.1.4.2 xref: GO:0047058 xref: MetaCyc:1.1.4.2-RXN is_a: CCO:F0003458 ! oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor [Term] id: CCO:F0006372 name: polyvinyl-alcohol dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: acceptor + polyvinyl alcohol = donor-H2 + oxidized polyvinyl alcohol." [EC:1.1.99.23, MetaCyc:1.1.99.23-RXN] subset: gosubset_prok synonym: "polyvinyl-alcohol:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.23] synonym: "polyvinyl-alcohol:acceptor oxidoreductase activity" EXACT [EC:1.1.99.23] synonym: "PVA dehydrogenase activity" EXACT [EC:1.1.99.23] xref: EC:1.1.99.23 xref: GO:0047059 xref: MetaCyc:1.1.99.23-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0006374 name: glucose-fructose oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: fructose + beta-D-glucose = D-sorbitol + glucono-delta-lactone." [EC:1.1.99.28, MetaCyc:1.1.99.28-RXN] subset: gosubset_prok synonym: "D-glucose:D-fructose oxidoreductase activity" EXACT [EC:1.1.99.28] xref: EC:1.1.99.28 xref: GO:0047061 xref: MetaCyc:1.1.99.28-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0006375 name: trans-acenaphthene-1,2-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + (+-)-trans-acenaphthene-1,2-diol = NADPH + H+ + acenaphthenequinone." [EC:1.10.1.1, MetaCyc:1.10.1.1-RXN] synonym: "(+-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase activity" EXACT [EC:1.10.1.1] synonym: "trans-1,2-acenaphthenediol dehydrogenase activity" EXACT [EC:1.10.1.1] xref: EC:1.10.1.1 xref: GO:0047062 xref: MetaCyc:1.10.1.1-RXN is_a: CCO:F0003271 ! oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor [Term] id: CCO:F0006376 name: L-ascorbate-cytochrome-b5 reductase activity namespace: molecular_function def: "Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate." [EC:1.10.2.1, MetaCyc:1.10.2.1-RXN] synonym: "ascorbate-cytochrome b5 reductase activity" EXACT [EC:1.10.2.1] synonym: "L-ascorbate:ferricytochrome-b5 oxidoreductase activity" EXACT [EC:1.10.2.1] xref: EC:1.10.2.1 xref: GO:0047063 xref: MetaCyc:1.10.2.1-RXN is_a: CCO:F0003272 ! oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor [Term] id: CCO:F0006377 name: sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2 sulochrin = 2 H2O + 2 (+)-bisdechlorogeodin." [EC:1.21.3.4, MetaCyc:1.10.3.7-RXN] synonym: "sulochrin oxidase activity" EXACT [EC:1.21.3.4] synonym: "sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)" EXACT [EC:1.21.3.4] xref: EC:1.21.3.4 xref: GO:0047064 xref: MetaCyc:1.10.3.7-RXN is_a: CCO:F0006307 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor [Term] id: CCO:F0006378 name: sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2 sulochrin = 2 H2O + 2 (-)-bisdechlorogeodin." [EC:1.21.3.5, MetaCyc:1.10.3.8-RXN] synonym: "sulochrin oxidase activity" BROAD [EC:1.21.3.5] synonym: "sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)" EXACT [EC:1.21.3.5] xref: EC:1.21.3.5 xref: GO:0047065 xref: MetaCyc:1.10.3.8-RXN is_a: CCO:F0006307 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor [Term] id: CCO:F0006379 name: phospholipid-hydroperoxide glutathione peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione." [EC:1.11.1.12, MetaCyc:1.11.1.12-RXN] synonym: "glutathione:lipid-hydroperoxide oxidoreductase activity" EXACT [EC:1.11.1.12] synonym: "hydroperoxide glutathione peroxidase activity" EXACT [EC:1.11.1.12] synonym: "peroxidation-inhibiting protein activity" RELATED [EC:1.11.1.12] synonym: "peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)" EXACT [EC:1.11.1.12] synonym: "PHGPX" RELATED [EC:1.11.1.12] synonym: "phospholipid hydroperoxide glutathione peroxidase activity" EXACT [EC:1.11.1.12] xref: EC:1.11.1.12 xref: GO:0047066 xref: MetaCyc:1.11.1.12-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0006380 name: hydrogen:quinone oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: menaquinone + H2 = reduced menaquinone." [EC:1.12.5.1, MetaCyc:1.12.99.3-RXN] subset: gosubset_prok synonym: "hydrogen-ubiquinone oxidoreductase activity" EXACT [EC:1.12.5.1] synonym: "hydrogen:menaquinone oxidoreductase activity" EXACT [EC:1.12.5.1] synonym: "membrane-bound hydrogenase activity" NARROW [EC:1.12.5.1] synonym: "quinone-reactive Ni/Fe-hydrogenase activity" RELATED [EC:1.12.5.1] xref: EC:1.12.5.1 xref: GO:0047067 xref: MetaCyc:1.12.5.1-RXN is_a: CCO:F0006308 ! oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor [Term] id: CCO:F0006381 name: N5,N10-methenyltetrahydromethanopterin hydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2 + N5,N10-methenyltetrahydromethanopterin = H+ + N5,N10-methylenetetrahydromethanopterin." [EC:1.12.98.2, MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN-RXN] subset: gosubset_prok synonym: "5,10-methenyltetrahydromethanopterin hydrogenase activity" EXACT [EC:1.12.98.2] synonym: "H(2)-dependent methylene-H(4)MPT dehydrogenase activity" EXACT [EC:1.12.98.2] synonym: "H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.12.98.2] synonym: "H2-dependent methylene-H4MPT dehydrogenase activity" EXACT [EC:1.12.98.2] synonym: "H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [EC:1.12.98.2] synonym: "hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase activity" EXACT [EC:1.12.98.2] synonym: "hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase activity" EXACT [EC:1.12.98.2] synonym: "hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase activity" EXACT [EC:1.12.98.2] synonym: "N(5),N(10)-methenyltetrahydromethanopterin hydrogenase activity" EXACT [EC:1.12.98.2] synonym: "N5,N10-methylenetetrahydromethanopterin dehydrogenase activity" EXACT [] synonym: "nonmetal hydrogenase activity" RELATED [EC:1.12.98.2] xref: EC:1.12.98.2 xref: GO:0016947 xref: GO:0047068 xref: MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN is_a: CCO:F0006309 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors [Term] id: CCO:F0006382 name: 7,8-dihydroxykynurenate 8,8a-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 7,8-dihydroxykynurenate = 5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylate." [EC:1.13.11.10, MetaCyc:1.13.11.10-RXN] synonym: "7,8-dihydroxykynurenate 8,8alpha-dioxygenase activity" EXACT [EC:1.13.11.10] synonym: "7,8-dihydroxykynurenate oxygenase activity" EXACT [EC:1.13.11.10] synonym: "7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.10] xref: EC:1.13.11.10 xref: GO:0047069 xref: MetaCyc:1.13.11.10-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006383 name: 3-carboxyethylcatechol 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate." [EC:1.13.11.16, MetaCyc:1.13.11.16-RXN] synonym: "2,3-dihydroxy-beta-phenylpropionate oxygenase activity" EXACT [EC:1.13.11.16] synonym: "2,3-dihydroxy-beta-phenylpropionic dioxygenase activity" EXACT [EC:1.13.11.16] synonym: "3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.16] synonym: "3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase activity" EXACT [EC:1.13.11.16] xref: EC:1.13.11.16 xref: GO:0047070 xref: MetaCyc:1.13.11.16-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006384 name: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate." [EC:1.13.11.25, MetaCyc:1.13.11.25-RXN] synonym: "3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.25] synonym: "3-alkylcatechol 2,3-dioxygenase activity" EXACT [EC:1.13.11.25] synonym: "steroid 4,5-dioxygenase activity" BROAD [EC:1.13.11.25] xref: EC:1.13.11.25 xref: GO:0047071 xref: MetaCyc:1.13.11.25-RXN xref: UM-BBD_enzymeID:e0715 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006385 name: 2,3-dihydroxybenzoate 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2,3-dihydroxybenzoate = 2-carboxy-cis,cis-muconate." [EC:1.13.11.28, MetaCyc:1.13.11.28-RXN] synonym: "2,3-dihydroxybenzoate 2,3-oxygenase activity" EXACT [EC:1.13.11.28] synonym: "2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.28] xref: EC:1.13.11.28 xref: GO:0047072 xref: MetaCyc:1.13.11.28-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006386 name: 2,4'-dihydroxyacetophenone dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2',4'-dihydroxyacetophenone = formate + p-hydroxybenzoate." [EC:1.13.11.41, MetaCyc:1.13.11.41-RXN] subset: gosubset_prok synonym: "(4-hydroxybenzoyl)methanol oxygenase activity" EXACT [EC:1.13.11.41] synonym: "2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving)" EXACT [EC:1.13.11.41] xref: EC:1.13.11.41 xref: GO:0047073 xref: MetaCyc:1.13.11.41-RXN xref: UM-BBD_enzymeID:e0889 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006387 name: 4-hydroxycatechol 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate." [EC:1.13.11.-, MetaCyc:R308-RXN] xref: EC:1.13.11.- xref: GO:0047074 xref: MetaCyc:R308-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006388 name: 2,5-dihydroxypyridine 5,6-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate." [EC:1.13.11.9, MetaCyc:1.13.11.9-RXN] synonym: "2,5-dihydroxypyridine oxygenase activity" EXACT [EC:1.13.11.9] synonym: "2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase activity" EXACT [EC:1.13.11.9] synonym: "pyridine-2,5-diol dioxygenase activity" EXACT [EC:1.13.11.9] xref: EC:1.13.11.9 xref: GO:0047075 xref: MetaCyc:1.13.11.9-RXN xref: UM-BBD_enzymeID:e0911 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006389 name: Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + pyrophosphate + AMP + CO2 + oxidized Photinus luciferin." [EC:1.13.12.7, MetaCyc:1.13.12.7-RXN] synonym: "firefly luciferase activity" EXACT [EC:1.13.12.7] synonym: "firefly luciferin luciferase activity" EXACT [EC:1.13.12.7] synonym: "luciferase (firefly luciferin)" EXACT [EC:1.13.12.7] synonym: "luciferase activity" BROAD [EC:1.13.12.7] synonym: "Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)" EXACT [EC:1.13.12.7] synonym: "Photinus pyralis luciferase activity" EXACT [EC:1.13.12.7] synonym: "Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)" EXACT [EC:1.13.12.7] synonym: "Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing)" EXACT [EC:1.13.12.7] xref: EC:1.13.12.7 xref: GO:0047077 xref: MetaCyc:1.13.12.7-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) is_a: CCO:F0006100 ! luciferin monooxygenase activity [Term] id: CCO:F0006390 name: 3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate." [EC:1.13.11.47, MetaCyc:1.13.11.47-RXN] subset: gosubset_prok synonym: "(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] synonym: "1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity" EXACT [] synonym: "3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)" EXACT [EC:1.13.11.47] synonym: "3-hydroxy-4(1H)-one, 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] synonym: "3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] synonym: "quinoline-3,4-diol 2,4-dioxygenase activity" EXACT [EC:1.13.11.47] xref: EC:1.13.11.47 xref: GO:0047078 xref: MetaCyc:1.13.11.47-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006391 name: pyrimidine-deoxynucleoside 1'-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2-oxoglutarate + deoxyuridine = CO2 + succinate + dioxyribonolactone + uracil." [EC:1.14.11.10, MetaCyc:1.14.11.10-RXN] synonym: "2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)" EXACT [EC:1.14.11.10] synonym: "deoxyuridine-uridine 1'-dioxygenase activity" EXACT [EC:1.14.11.10] synonym: "pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity" EXACT [EC:1.14.11.10] xref: EC:1.14.11.10 xref: GO:0047079 xref: MetaCyc:1.14.11.10-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006392 name: pyrimidine-deoxynucleoside 2'-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2-oxoglutarate + deoxyuridine = CO2 + succinate + uridine." [EC:1.14.11.3, MetaCyc:1.14.11.3-RXN] synonym: "2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)" EXACT [EC:1.14.11.3] synonym: "deoxyuridine 2'-dioxygenase activity" EXACT [EC:1.14.11.3] synonym: "deoxyuridine 2'-hydroxylase activity" EXACT [EC:1.14.11.3] synonym: "pyrimidine deoxyribonucleoside 2'-hydroxylase activity" EXACT [EC:1.14.11.3] synonym: "pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase activity" EXACT [EC:1.14.11.3] synonym: "thymidine 2'-dioxygenase activity" NARROW [EC:1.14.11.3] synonym: "thymidine 2'-hydroxylase activity" NARROW [EC:1.14.11.3] synonym: "thymidine 2-oxoglutarate dioxygenase activity" NARROW [EC:1.14.11.3] synonym: "thymidine dioxygenase activity" NARROW [EC:1.14.11.3] xref: EC:1.14.11.3 xref: GO:0047080 xref: MetaCyc:1.14.11.3-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006393 name: 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NAD(P)H + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NAD(P)+ + 2-(acetamidomethylene)succinate." [EC:1.14.12.4, MetaCyc:1.14.12.4-RXN] synonym: "2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase activity" EXACT [EC:1.14.12.4] synonym: "3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing)" EXACT [EC:1.14.12.4] synonym: "3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity" EXACT [EC:1.14.12.4] synonym: "methylhydroxypyridine carboxylate dioxygenase activity" EXACT [EC:1.14.12.4] synonym: "methylhydroxypyridinecarboxylate oxidase activity" EXACT [EC:1.14.12.4] xref: EC:1.14.12.4 xref: GO:0047081 xref: MetaCyc:1.14.12.4-RXN is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0006394 name: 3,9-dihydroxypterocarpan 6a-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + (6aR,11aR)-3,9-dihydroxypterocarpan = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol." [EC:1.14.13.28, MetaCyc:1.14.13.28-RXN] synonym: "(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating)" EXACT [EC:1.14.13.28] synonym: "3,9-dihydroxypterocarpan 6a-hydroxylase activity" EXACT [] synonym: "3,9-dihydroxypterocarpan 6alpha-monooxygenase (erroneous)" EXACT [EC:1.14.13.28] xref: EC:1.14.13.28 xref: GO:0047082 xref: MetaCyc:RXN-4505 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006395 name: 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate." [EC:1.14.13.36, MetaCyc:1.14.13.36-RXN] synonym: "5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase activity" EXACT [] synonym: "coumaroylquinate(coumaroylshikimate) 3'-monooxygenase activity" EXACT [EC:1.14.13.36] synonym: "trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.13.36] xref: EC:1.14.13.36 xref: GO:0047083 xref: MetaCyc:1.14.13.36-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006396 name: methyltetrahydroprotoberberine 14-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine." [EC:1.14.13.37, MetaCyc:1.14.13.37-RXN] synonym: "(S)-cis-N-methyltetrahydroberberine 14-monooxygenase activity" EXACT [EC:1.14.13.37] synonym: "(S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase activity" EXACT [EC:1.14.13.37] synonym: "(S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)" EXACT [EC:1.14.13.37] synonym: "methyltetrahydroprotoberberine 14-hydroxylase activity" EXACT [] xref: EC:1.14.13.37 xref: GO:0047084 xref: MetaCyc:1.14.13.37-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006397 name: hydroxyphenylacetonitrile 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + 4-hydroxyphenylacetonitrile = H2O + NADP+ + 4-hydroxymandelonitrile." [EC:1.14.13.42, MetaCyc:1.14.13.42-RXN] synonym: "4-hydroxyphenylacetonitrile hydroxylase activity" EXACT [EC:1.14.13.42] synonym: "4-hydroxyphenylacetonitrile monooxygenase activity" EXACT [] synonym: "4-hydroxyphenylacetonitrile,NADPH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.42] xref: EC:1.14.13.42 xref: GO:0047085 xref: MetaCyc:1.14.13.42-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006398 name: ketosteroid monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate." [EC:1.14.13.54, MetaCyc:1.14.13.54-RXN] synonym: "17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)" EXACT [EC:1.14.13.54] synonym: "androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)" EXACT [EC:1.14.13.54] synonym: "ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)" EXACT [EC:1.14.13.54] synonym: "progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)" EXACT [EC:1.14.13.54] synonym: "steroid-ketone monooxygenase activity" EXACT [EC:1.14.13.54] xref: EC:1.14.13.54 xref: GO:0047086 xref: MetaCyc:1.14.13.54-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006399 name: protopine 6-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + protopine = H2O + NADP+ + 6-hydroxyprotopine." [EC:1.14.13.55, MetaCyc:1.14.13.55-RXN] synonym: "protopine 6-hydroxylase activity" EXACT [] synonym: "protopine,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.55] xref: EC:1.14.13.55 xref: GO:0047087 xref: MetaCyc:1.14.13.55-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006400 name: dihydrosanguinarine 10-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + dihydrosanguinarine = H2O + NADP+ + 10-hydroxydihydrosanguinarine." [EC:1.14.13.56, MetaCyc:1.14.13.56-RXN] synonym: "dihydrosanguinarine 10-hydroxylase activity" EXACT [] synonym: "dihydrosanguinarine,NADPH:oxygen oxidoreductase (10-hydroxylating)" EXACT [EC:1.14.13.56] xref: EC:1.14.13.56 xref: GO:0047088 xref: MetaCyc:1.14.13.56-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006401 name: dihydrochelirubine 12-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + dihydrochelirubine = H2O + NADP+ + 10-hydroxydihydrochelirubine." [EC:1.14.13.57, MetaCyc:1.14.13.57-RXN] synonym: "dihydrochelirubine 12-hydroxylase activity" EXACT [] synonym: "dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)" EXACT [EC:1.14.13.57] xref: EC:1.14.13.57 xref: GO:0047089 xref: MetaCyc:1.14.13.57-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006402 name: benzoyl-CoA 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: benzoyl-CoA + O2 + NADPH = H2O + NADP+ + 3-hydroxybenzoyl-CoA." [EC:1.14.13.58, MetaCyc:1.14.13.58-RXN] synonym: "benzoyl-CoA 3-hydroxylase activity" EXACT [] synonym: "benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.58] xref: EC:1.14.13.58 xref: GO:0047090 xref: MetaCyc:1.14.13.58-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006403 name: L-lysine 6-monooxygenase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + L-lysine = H2O + NADP+ + N6-hydroxy-L-lysine." [EC:1.14.13.59, MetaCyc:1.14.13.59-RXN] comment: Note that EC:1.13.12.10 was merged into this term. subset: gosubset_prok synonym: "L-lysine 6-monooxygenase activity" EXACT [] synonym: "L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.59] synonym: "lysine N(6)-hydroxylase activity" EXACT [EC:1.14.13.59] synonym: "lysine N6-hydroxylase activity" EXACT [] xref: EC:1.14.13.59 xref: GO:0008739 xref: GO:0047091 xref: MetaCyc:1.14.13.59-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006404 name: 27-hydroxycholesterol 7-alpha-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol." [EC:1.14.13.60, MetaCyc:1.14.13.60-RXN] synonym: "27-hydroxycholesterol 7-alpha-hydroxylase activity" EXACT [EC:1.14.13.60] synonym: "27-hydroxycholesterol 7a-hydroxylase activity" EXACT [] synonym: "27-hydroxycholesterol 7alpha-hydroxylase activity" EXACT [EC:1.14.13.60] synonym: "27-hydroxycholesterol 7alpha-monooxygenase activity" EXACT [EC:1.14.13.60] synonym: "27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" EXACT [EC:1.14.13.60] xref: EC:1.14.13.60 xref: GO:0047092 xref: MetaCyc:1.14.13.60-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006405 name: 4-hydroxyquinoline 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADH + quinolin-4-ol = H2O + NAD+ + quinolin-3,4-diol." [EC:1.14.13.62, MetaCyc:1.14.13.62-RXN] synonym: "1-H-4-oxoquinoline 3-monooxygenase activity" EXACT [EC:1.14.13.62] synonym: "quinolin-4(1H)-one 3-monooxygenase activity" EXACT [EC:1.14.13.62] synonym: "quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating)" EXACT [EC:1.14.13.62] xref: EC:1.14.13.62 xref: GO:0047093 xref: MetaCyc:1.14.13.62-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006406 name: 3-hydroxyphenylacetate 6-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate." [EC:1.14.13.63, MetaCyc:1.14.13.63-RXN] synonym: "3-hydroxyphenylacetate 6-monooxygenase activity" EXACT [EC:1.14.13.63] synonym: "3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.63] xref: EC:1.14.13.63 xref: GO:0047094 xref: MetaCyc:1.14.13.63-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006407 name: 2-hydroxycyclohexanone 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + 2-hydroxycyclohexan-1-one = H2O + NADP+ + 6-hydroxyhexan-6-olide." [EC:1.14.13.66, MetaCyc:1.14.13.66-RXN] synonym: "2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing)" EXACT [EC:1.14.13.66] xref: EC:1.14.13.66 xref: GO:0047095 xref: MetaCyc:1.14.13.66-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006408 name: androst-4-ene-3,17-dione monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + donor-H2 + androst-4-ene-3,17-dione = H2O + acceptor + 3-oxo-13,17-secoandrost-4-eno-17,13-alpha-lactone." [EC:1.14.99.12, MetaCyc:1.14.99.12-RXN] synonym: "4-androstene-3,17-dione monooxygenase activity" EXACT [] synonym: "androst-4-ene-3,17-dione 17-oxidoreductase activity" EXACT [EC:1.14.99.12] synonym: "androst-4-ene-3,17-dione hydroxylase activity" EXACT [EC:1.14.99.12] synonym: "androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing)" EXACT [EC:1.14.99.12] synonym: "androstene-3,17-dione hydroxylase activity" EXACT [] synonym: "androstenedione monooxygenase activity" EXACT [EC:1.14.99.12] xref: EC:1.14.99.12 xref: GO:0047096 xref: MetaCyc:1.14.99.12-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0006409 name: phylloquinone monooxygenase (2,3-epoxidizing) activity namespace: molecular_function def: "Catalysis of the reaction: O2 + donor-H2 + vitamin K1 = H2O + acceptor + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone." [EC:1.14.99.20, MetaCyc:1.14.99.20-RXN] synonym: "phylloquinone epoxidase activity" EXACT [EC:1.14.99.20] synonym: "phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)" EXACT [EC:1.14.99.20] synonym: "vitamin K 2,3-epoxidase activity" EXACT [EC:1.14.99.20] synonym: "vitamin K epoxidase activity" EXACT [EC:1.14.99.20] synonym: "vitamin K1 epoxidase activity" EXACT [EC:1.14.99.20] xref: EC:1.14.99.20 xref: GO:0047097 xref: MetaCyc:1.14.99.20-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0006410 name: Latia-luciferin monooxygenase (demethylating) activity namespace: molecular_function def: "Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin." [EC:1.14.99.21, MetaCyc:1.14.99.21-RXN] synonym: "Latia luciferin monooxygenase (demethylating)" EXACT [EC:1.14.99.21] synonym: "Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)" EXACT [EC:1.14.99.21] synonym: "luciferase (Latia luciferin)" EXACT [EC:1.14.99.21] xref: EC:1.14.99.21 xref: GO:0047098 xref: MetaCyc:1.14.99.21-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is_a: CCO:F0006100 ! luciferin monooxygenase activity [Term] id: CCO:F0006411 name: CDP-4-dehydro-6-deoxyglucose reductase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose." [EC:1.17.1.1, MetaCyc:1.17.1.1-RXN] synonym: "CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity" EXACT [EC:1.17.1.1] synonym: "CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity" EXACT [EC:1.17.1.1] synonym: "CDP-4-keto-6-deoxyglucose reductase activity" EXACT [EC:1.17.1.1] synonym: "CDP-4-keto-deoxy-glucose reductase activity" EXACT [EC:1.17.1.1] synonym: "cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity" EXACT [EC:1.17.1.1] synonym: "cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity" EXACT [EC:1.17.1.1] synonym: "NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity" EXACT [EC:1.17.1.1] xref: EC:1.17.1.1 xref: GO:0047099 xref: MetaCyc:1.17.1.1-RXN is_a: CCO:F0003308 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [Term] id: CCO:F0006412 name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity namespace: molecular_function def: "Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate." [EC:1.2.1.13, MetaCyc:1.2.1.13-RXN] synonym: "D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)" EXACT [EC:1.2.1.13] synonym: "dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)" EXACT [EC:1.2.1.13] synonym: "glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)" EXACT [EC:1.2.1.13] synonym: "NADP-dependent glyceraldehyde phosphate dehydrogenase activity" EXACT [EC:1.2.1.13] synonym: "NADP-dependent glyceraldehyde-3-phosphate dehydrogenase activity" EXACT [EC:1.2.1.13] synonym: "NADP-triose phosphate dehydrogenase activity" EXACT [EC:1.2.1.13] synonym: "triosephosphate dehydrogenase (NADP(+)) activity" EXACT [EC:1.2.1.13] synonym: "triosephosphate dehydrogenase (NADP)" EXACT [EC:1.2.1.13] synonym: "triosephosphate dehydrogenase (NADP+) activity" EXACT [EC:1.2.1.13] xref: EC:1.2.1.13 xref: GO:0047100 xref: MetaCyc:1.2.1.13-RXN is_a: CCO:F0002279 ! glyceraldehyde-3-phosphate dehydrogenase activity [Term] id: CCO:F0006413 name: 2-oxoisovalerate dehydrogenase (acylating) activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA." [EC:1.2.1.25, MetaCyc:1.2.1.25-RXN] synonym: "2-oxoisovalerate dehydrogenase activity" EXACT [EC:1.2.1.25] synonym: "3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)" EXACT [EC:1.2.1.25] xref: EC:1.2.1.25 xref: GO:0047101 xref: MetaCyc:1.2.1.25-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006414 name: aminomuconate-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate." [EC:1.2.1.32, MetaCyc:1.2.1.32-RXN] synonym: "2-aminomuconate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] synonym: "2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase activity" EXACT [EC:1.2.1.32] synonym: "2-hydroxymuconate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] synonym: "2-hydroxymuconic acid semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] synonym: "2-hydroxymuconic semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] synonym: "alpha-aminomuconic epsilon-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] synonym: "alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.32] xref: EC:1.2.1.32 xref: GO:0047102 xref: MetaCyc:1.2.1.32-RXN xref: Reactome:82529 xref: UM-BBD_enzymeID:e0904 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006415 name: 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate." [EC:1.2.1.40, MetaCyc:1.2.1.40-RXN] synonym: "3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase activity" EXACT [EC:1.2.1.40] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al dehydrogenase activity" EXACT [EC:1.2.1.40] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase activity" EXACT [EC:1.2.1.40] synonym: "3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-dehydrogenase activity" EXACT [EC:1.2.1.40] synonym: "3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase activity" EXACT [EC:1.2.1.40] synonym: "cholestanetriol-26-al 26-dehydrogenase activity" EXACT [EC:1.2.1.40] synonym: "THAL-NAD oxidoreductase activity" EXACT [EC:1.2.1.40] synonym: "trihydroxydeoxycoprostanal dehydrogenase activity" EXACT [EC:1.2.1.40] xref: EC:1.2.1.40 xref: GO:0047103 xref: MetaCyc:1.2.1.40-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006416 name: hexadecanal dehydrogenase (acylating) activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + CoA + palmitaldehyde = NADH + palmityl-CoA." [EC:1.2.1.42, MetaCyc:1.2.1.42-RXN] synonym: "fatty acyl-CoA reductase activity" BROAD [EC:1.2.1.42] synonym: "hexadecanal:NAD+ oxidoreductase (CoA-acylating)" EXACT [EC:1.2.1.42] xref: EC:1.2.1.42 xref: GO:0047104 xref: MetaCyc:1.2.1.42-RXN xref: UM-BBD_enzymeID:e0853 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006417 name: 4-trimethylammoniobutyraldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate." [EC:1.2.1.47, MetaCyc:1.2.1.47-RXN] synonym: "4-N-trimethylaminobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.47] synonym: "4-trimethylaminobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.47] synonym: "4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity" EXACT [EC:1.2.1.47] xref: EC:1.2.1.47 xref: GO:0047105 xref: MetaCyc:1.2.1.47-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006418 name: 4-hydroxyphenylacetaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate." [EC:1.2.1.53, MetaCyc:1.2.1.53-RXN] synonym: "4-HPAL dehydrogenase activity" EXACT [EC:1.2.1.53] synonym: "4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.53] xref: EC:1.2.1.53 xref: GO:0047106 xref: MetaCyc:1.2.1.53-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006419 name: gamma-guanidinobutyraldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NAD+ + 4-guanidinobutanal = NADH + 4-guanidinobutanoate." [EC:1.2.1.54, MetaCyc:1.2.1.54-RXN] synonym: "4-guanidinobutanal:NAD+ 1-oxidoreductase activity" EXACT [EC:1.2.1.54] synonym: "4-guanidinobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.54] synonym: "alpha-guanidinobutyraldehyde dehydrogenase activity" EXACT [EC:1.2.1.54] synonym: "GBAL dehydrogenase activity" EXACT [EC:1.2.1.54] xref: EC:1.2.1.54 xref: GO:0047107 xref: MetaCyc:1.2.1.54-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006422 name: phenylglyoxylate dehydrogenase (acylating) activity namespace: molecular_function def: "Catalysis of the reaction: CoA + NAD+ + phenylglyoxylate = NADH + CO2 + benzoyl-S-CoA." [EC:1.2.1.58, MetaCyc:1.2.1.58-RXN] synonym: "phenylglyoxylate:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.58] xref: EC:1.2.1.58 xref: GO:0047110 xref: MetaCyc:1.2.1.58-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006423 name: formate dehydrogenase (cytochrome-c-553) activity namespace: molecular_function def: "Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2." [EC:1.2.2.3, MetaCyc:1.2.2.3-RXN] synonym: "formate dehydrogenase (cytochrome c-553)" EXACT [EC:1.2.2.3] synonym: "formate:ferricytochrome-c-553 oxidoreductase activity" EXACT [EC:1.2.2.3] xref: EC:1.2.2.3 xref: GO:0047111 xref: MetaCyc:1.2.2.3-RXN is_a: CCO:F0003224 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor [Term] id: CCO:F0006424 name: pyruvate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + phosphate + pyruvate = H2O2 + CO2 + acetylphosphate." [EC:1.2.3.3, MetaCyc:1.2.3.3-RXN] subset: gosubset_prok synonym: "phosphate-dependent pyruvate oxidase activity" EXACT [EC:1.2.3.3] synonym: "pyruvate:oxygen 2-oxidoreductase (phosphorylating)" EXACT [EC:1.2.3.3] synonym: "pyruvic oxidase activity" EXACT [EC:1.2.3.3] xref: EC:1.2.3.3 xref: GO:0047112 xref: MetaCyc:1.2.3.3-RXN is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0006425 name: aldehyde dehydrogenase (pyrroloquinoline-quinone) activity namespace: molecular_function def: "Catalysis of the reaction: H2O + acceptor + an aldehyde = donor-H2 + an acid." [EC:1.2.99.3, MetaCyc:1.2.99.3-RXN] subset: gosubset_prok synonym: "aldehyde dehydrogenase (acceptor) activity" EXACT [EC:1.2.99.3] synonym: "aldehyde:(pyrroloquinoline-quinone) oxidoreductase activity" EXACT [EC:1.2.99.3] xref: EC:1.2.99.3 xref: GO:0047113 xref: MetaCyc:1.2.99.3-RXN is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0006426 name: kynurenate-7,8-dihydrodiol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 7,8-dihydro-7,8-dihydroxykynurenate = NADH + 7,8-dihydroxykynurenate." [EC:1.3.1.18, MetaCyc:1.3.1.18-RXN] synonym: "7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase activity" EXACT [EC:1.3.1.18] synonym: "7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.18] synonym: "7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase activity" EXACT [EC:1.3.1.18] xref: EC:1.3.1.18 xref: GO:0047114 xref: MetaCyc:1.3.1.18-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006427 name: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol." [EC:1.3.1.20, MetaCyc:1.3.1.20-RXN] subset: gosubset_prok synonym: "dihydrodiol dehydrogenase activity" EXACT [EC:1.3.1.20] synonym: "trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.20] xref: EC:1.3.1.20 xref: GO:0047115 xref: MetaCyc:1.3.1.20-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006428 name: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol." [EC:1.3.1.25, MetaCyc:1.3.1.25-RXN] synonym: "(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.25] synonym: "2-hydro-1,2-dihydroxybenzoate dehydrogenase activity" EXACT [EC:1.3.1.25] synonym: "3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity" EXACT [EC:1.3.1.25] synonym: "3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity" EXACT [EC:1.3.1.25] synonym: "cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity" EXACT [EC:1.3.1.25] synonym: "cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.25] synonym: "DHB dehydrogenase activity" EXACT [EC:1.3.1.25] synonym: "DHBDH activity" EXACT [EC:1.3.1.25] synonym: "dihydrodihydroxybenzoate dehydrogenase activity" EXACT [EC:1.3.1.25] xref: EC:1.3.1.25 xref: GO:0047116 xref: MetaCyc:1.3.1.25-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006429 name: enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity namespace: molecular_function def: "Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+." [EC:1.3.1.39, MetaCyc:1.3.1.39-RXN] synonym: "acyl-acyl-carrier-protein:NADP+ oxidoreductase (A-specific)" EXACT [EC:1.3.1.39] synonym: "enoyl-[acyl-carrier protein] reductase (NADPH, A-specific) activity" EXACT [] synonym: "enoyl-ACP reductase (NADPH, A-specific) activity" EXACT [] synonym: "enoyl-ACp reductase activity" EXACT [EC:1.3.1.39] synonym: "enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.3.1.39] synonym: "enoyl-acyl-carrier-protein reductase (NADPH, A-specific)" EXACT [EC:1.3.1.39] xref: EC:1.3.1.39 xref: GO:0047117 xref: MetaCyc:1.3.1.39-RXN is_a: CCO:F0003232 ! enoyl-[acyl-carrier-protein] reductase activity [Term] id: CCO:F0006430 name: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 2,6-dioxo-6-phenylhexanoate = NADPH + 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate." [EC:1.3.1.40, MetaCyc:1.3.1.40-RXN] synonym: "2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.40] synonym: "2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.3.1.40] xref: EC:1.3.1.40 xref: GO:0047118 xref: MetaCyc:1.3.1.40-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006431 name: 2-methyl-branched-chain-enoyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + 2-methylbutyryl-CoA = NADH + 2-methylcrotonoyl-CoA." [EC:1.3.1.52, MetaCyc:1.3.1.52-RXN] synonym: "2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase activity" EXACT [EC:1.3.1.52] xref: EC:1.3.1.52 xref: GO:0047119 xref: MetaCyc:1.3.1.52-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006433 name: isoquinoline 1-oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + acceptor + isoquinoline = donor-H2 + isoquinolin-12H-one." [EC:1.3.99.16, MetaCyc:1.3.99.16-RXN] subset: gosubset_prok synonym: "isoquinoline:acceptor 1-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.16] xref: EC:1.3.99.16 xref: GO:0047121 xref: MetaCyc:1.3.99.16-RXN is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0006434 name: quinaldate 4-oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + acceptor + quinaldate = donor-H2 + kynurenate." [EC:1.3.99.18, MetaCyc:1.3.99.18-RXN] synonym: "quinaldic acid 4-oxidoreductase activity" EXACT [EC:1.3.99.18] synonym: "quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.18] xref: EC:1.3.99.18 xref: GO:0047122 xref: MetaCyc:1.3.99.18-RXN is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0006435 name: quinoline-4-carboxylate 2-oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + acceptor + quinoline-4-carboxylate = quinolin-2-ol + donor-H2." [EC:1.3.99.19, MetaCyc:1.3.99.19-RXN] synonym: "quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.19] synonym: "quinoline-4-carboxylic acid 2-oxidoreductase activity" EXACT [EC:1.3.99.19] xref: EC:1.3.99.19 xref: GO:0047123 xref: MetaCyc:1.3.99.19-RXN is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0006436 name: L-erythro-3,5-diaminohexanoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + H2O + (3S,5S)-3,5-diaminohexanoate = NADH + NH3 + (S)-5-amino-3-oxohexanoate." [EC:1.4.1.11, MetaCyc:1.4.1.11-RXN] synonym: "L-3,5-diaminohexanoate dehydrogenase activity" EXACT [EC:1.4.1.11] synonym: "L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.11] xref: EC:1.4.1.11 xref: GO:0047124 xref: MetaCyc:1.4.1.11-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006437 name: delta1-piperideine-2-carboxylate reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta(1)-piperideine-2-carboxylate." [EC:1.5.1.21, MetaCyc:1.5.1.21-RXN] synonym: "1,2-didehydropipecolate reductase activity" EXACT [EC:1.5.1.21] synonym: "1,2-didehydropipecolic reductase activity" EXACT [EC:1.5.1.21] synonym: "D1-piperideine-2-carboxylate reductase activity" EXACT [] synonym: "delta 1-piperideine-2-carboxylate reductase activity" EXACT [] synonym: "L-pipecolate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.5.1.21] synonym: "P2C reductase activity" EXACT [EC:1.5.1.21] xref: EC:1.5.1.21 xref: GO:0047125 xref: MetaCyc:1.5.1.21-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006438 name: N5-(carboxyethyl)ornithine synthase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NADP+ + N5-(L-1-carboxyethyl)-L-ornithine = NADPH + pyruvate + L-ornithine." [EC:1.5.1.24, MetaCyc:1.5.1.24-RXN] subset: gosubset_prok synonym: "5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)" EXACT [EC:1.5.1.24] synonym: "N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)" EXACT [EC:1.5.1.24] xref: EC:1.5.1.24 xref: GO:0047126 xref: MetaCyc:1.5.1.24-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006439 name: thiomorpholine-carboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate." [EC:1.5.1.25, MetaCyc:1.5.1.25-RXN] synonym: "ketimine reductase activity" EXACT [EC:1.5.1.25] synonym: "ketimine-reducing enzyme" RELATED [EC:1.5.1.25] synonym: "thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity" EXACT [EC:1.5.1.25] xref: EC:1.5.1.25 xref: GO:0047127 xref: MetaCyc:1.5.1.25-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006440 name: 1,2-dehydroreticulinium reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + 1,2-dehydroreticulinium = NADP+ + R-reticuline." [EC:1.5.1.27, MetaCyc:1.5.1.27-RXN] synonym: "(R)-reticuline:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.27] synonym: "1,2-dehydroreticulinium ion reductase activity" EXACT [EC:1.5.1.27] xref: EC:1.5.1.27 xref: GO:0047128 xref: MetaCyc:1.5.1.27-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006441 name: opine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NAD+ + (2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate = NADH + pyruvate + L-2-aminopentanoic acid." [EC:1.5.1.28, MetaCyc:1.5.1.28-RXN] subset: gosubset_prok synonym: "(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD, L-aminopentanoate-forming)" EXACT [EC:1.5.1.28] synonym: "(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming)" EXACT [EC:1.5.1.28] xref: EC:1.5.1.28 xref: GO:0047129 xref: MetaCyc:1.5.1.28-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006442 name: saccharopine dehydrogenase (NADP+, L-lysine-forming) activity namespace: molecular_function def: "Catalysis of the reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-lysine + 2-oxoglutarate + NADPH + H+." [EC:1.5.1.8, MetaCyc:1.5.1.8-RXN] subset: gosubset_prok synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.8] synonym: "L-lysine-alpha-ketoglutarate reductase activity" EXACT [EC:1.5.1.8] synonym: "lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)" EXACT [EC:1.5.1.8] synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.8] synonym: "saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity" EXACT [EC:1.5.1.8] xref: EC:1.5.1.8 xref: GO:0010010 xref: GO:0047130 xref: MetaCyc:1.5.1.8-RXN is_a: CCO:F0001117 ! saccharopine dehydrogenase activity [Term] id: CCO:F0006443 name: saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity namespace: molecular_function def: "Catalysis of the reaction: 6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADH + H+." [EC:1.5.1.9, MetaCyc:1.5.1.9-RXN] synonym: "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.9] synonym: "aminoadipic semialdehyde synthase activity" EXACT [EC:1.5.1.9] synonym: "dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming)" EXACT [EC:1.5.1.9] synonym: "N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)" EXACT [EC:1.5.1.9] synonym: "NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming)" EXACT [EC:1.5.1.9] synonym: "saccharopin dehydrogenase activity" EXACT [EC:1.5.1.9] xref: EC:1.5.1.9 xref: GO:0047131 xref: MetaCyc:1.5.1.9-RXN is_a: CCO:F0001117 ! saccharopine dehydrogenase activity [Term] id: CCO:F0006444 name: dihydrobenzophenanthridine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine." [EC:1.5.3.12, MetaCyc:1.5.3.12-RXN] synonym: "dihydrobenzophenanthridine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.12] xref: EC:1.5.3.12 xref: GO:0047132 xref: MetaCyc:1.5.3.12-RXN is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0006445 name: dimethylamine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine." [EC:1.5.8.1, MetaCyc:1.5.8.1-RXN] subset: gosubset_prok synonym: "dimethylamine:electron-transferring flavoprotein oxidoreductase activity" EXACT [EC:1.5.8.1] synonym: "DMADh activity" EXACT [EC:1.5.8.1] xref: EC:1.5.8.1 xref: GO:0047133 xref: MetaCyc:1.5.8.1-RXN xref: UM-BBD_enzymeID:e0855 is_a: CCO:F0006311 ! oxidoreductase activity, acting on the CH-NH group of donors, with a flavin as acceptor [Term] id: CCO:F0006446 name: protein-disulfide reductase activity namespace: molecular_function def: "Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+." [EC:1.8.1.8, MetaCyc:1.6.4.4-RXN] subset: gosubset_prok synonym: "disulfide reductase activity" EXACT [EC:1.8.1.8] synonym: "insulin-glutathione transhydrogenase activity" EXACT [EC:1.8.1.8] synonym: "NAD(P)H2:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.1.8] synonym: "NAD(P)H:protein-disulfide oxidoreductase activity" EXACT [EC:1.8.1.8] synonym: "protein disulfide reductase activity" EXACT [EC:1.8.1.8] synonym: "protein disulphide reductase activity" EXACT [EC:1.8.1.8] synonym: "protein-disulfide reductase (NAD(P)H) activity" EXACT [] synonym: "protein-disulphide reductase activity" EXACT [] synonym: "protein-dithiol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.8.1.8] xref: EC:1.8.1.8 xref: GO:0047134 xref: MetaCyc:1.6.4.4-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006447 name: bis-gamma-glutamylcystine reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 gamma-glutamylcysteine + NADP+ = bis-gamma-glutamylcystine + NADPH + H+." [EC:1.8.1.13, MetaCyc:1.6.4.9-RXN] synonym: "bis-g-glutamylcystine reductase (NADPH) activity" EXACT [] synonym: "Bis-gamma-glutamylcystine reductase (NADPH)" EXACT [EC:1.8.1.13] synonym: "bis-gamma-glutamylcystine reductase (NADPH) activity" EXACT [EC:1.8.1.13] synonym: "gamma-glutamylcysteine:NADP+ oxidoreductase activity" EXACT [EC:1.8.1.13] synonym: "NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity" EXACT [EC:1.8.1.13] synonym: "NADPH:bis-gamma-glutamylcysteine oxidoreductase activity" EXACT [EC:1.8.1.13] xref: EC:1.8.1.13 xref: GO:0047135 xref: MetaCyc:1.6.4.9-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006448 name: 4-(dimethylamino)phenylazoxybenzene reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-dimethylaminophenylazobenzene + NADP+ = 4-(dimethylamino)phenylazoxybenzene + NADPH + H+." [EC:1.7.1.11, MetaCyc:1.6.6.12-RXN] synonym: "4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.11] synonym: "dimethylaminoazobenzene N-oxide reductase activity" EXACT [EC:1.7.1.11] synonym: "N,N-dimethyl-p-aminoazobenzene oxide reductase activity" EXACT [EC:1.7.1.11] synonym: "NADPH-dependent DMAB N-oxide reductase activity" EXACT [EC:1.7.1.11] synonym: "NADPH2:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity" EXACT [EC:1.7.1.11] synonym: "NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity" EXACT [EC:1.7.1.11] xref: EC:1.7.1.11 xref: GO:0047136 xref: MetaCyc:1.6.6.12-RXN is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0006449 name: N-hydroxy-2-acetamidofluorene reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+." [EC:1.7.1.12, MetaCyc:1.7.1.12-RXN] synonym: "2-acetamidofluorene:NAD(P)+ oxidoreductase activity" EXACT [EC:1.7.1.12] synonym: "N-hydroxy-2-acetylaminofluorene reductase activity" EXACT [EC:1.7.1.12] synonym: "NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity" EXACT [EC:1.7.1.12] synonym: "NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity" EXACT [EC:1.7.1.12] xref: EC:1.7.1.12 xref: GO:0047137 xref: MetaCyc:1.7.1.12-RXN is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0006450 name: aquacobalamin reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+." [EC:1.16.1.3, MetaCyc:1.6.99.12-RXN] subset: gosubset_prok synonym: "aquocobalamin reductase activity" EXACT [EC:1.16.1.3] synonym: "B(12a) reductase activity" EXACT [EC:1.16.1.3] synonym: "B12a reductase activity" EXACT [EC:1.16.1.3] synonym: "cob(II)alamin:NAD+ oxidoreductase activity" EXACT [EC:1.16.1.3] synonym: "NADH-linked aquacobalamin reductase activity" EXACT [EC:1.16.1.3] synonym: "NADH2:cob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.3] synonym: "NADH:cob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.3] synonym: "vitamin B(12a) reductase activity" EXACT [EC:1.16.1.3] synonym: "vitamin B12a reductase activity" EXACT [EC:1.16.1.3] xref: EC:1.16.1.3 xref: GO:0047138 xref: MetaCyc:AQUACOBALAMIN-REDUCTASE-RXN is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0006451 name: glutathione-homocystine transhydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine." [EC:1.8.4.1, MetaCyc:1.8.4.1-RXN] synonym: "glutathione:homocystine oxidoreductase activity" EXACT [EC:1.8.4.1] xref: EC:1.8.4.1 xref: GO:0047139 xref: MetaCyc:1.8.4.1-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0006452 name: glutathione-CoA-glutathione transhydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione." [EC:1.8.4.3, MetaCyc:1.8.4.3-RXN] synonym: "CoA:glutathione-disulfide oxidoreductase activity" EXACT [EC:1.8.4.3] synonym: "coenzyme A:glutathione-disulfide oxidoreductase activity" EXACT [EC:1.8.4.3] synonym: "coenzyme A:oxidized-glutathione oxidoreductase activity" EXACT [EC:1.8.4.3] synonym: "glutathione coenzyme A-glutathione transhydrogenase activity" EXACT [EC:1.8.4.3] synonym: "glutathione-coenzyme A glutathione disulfide transhydrogenase activity" EXACT [EC:1.8.4.3] synonym: "glutathione:coenzyme A-glutathione transhydrogenase activity" EXACT [EC:1.8.4.3] xref: EC:1.8.4.3 xref: GO:0047140 xref: MetaCyc:1.8.4.3-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0006453 name: glutathione-cystine transhydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine." [EC:1.8.4.4, MetaCyc:1.8.4.4-RXN] synonym: "glutathione:cystine oxidoreductase" EXACT [EC:1.8.4.4] synonym: "GSH-cystine transhydrogenase" EXACT [EC:1.8.4.4] synonym: "NADPH-dependent GSH-cystine transhydrogenase" EXACT [EC:1.8.4.4] xref: EC:1.8.4.4 xref: GO:0047141 xref: MetaCyc:1.8.4.4-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0006454 name: enzyme-thiol transhydrogenase (glutathione-disulfide) activity namespace: molecular_function def: "Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase." [EC:1.8.4.7, MetaCyc:1.8.4.7-RXN] synonym: "[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase activity" EXACT [EC:1.8.4.7] synonym: "enzyme-thiol transhydrogenase (glutathione-disulphide) activity" EXACT [] synonym: "enzyme-thiol transhydrogenase (oxidized-glutathione) activity" EXACT [] synonym: "glutathione-dependent thiol:disulfide oxidoreductase activity" EXACT [EC:1.8.4.7] synonym: "thiol:disulfide oxidoreductase activity" EXACT [EC:1.8.4.7] synonym: "thiol:disulphide oxidoreductase activity" EXACT [EC:1.8.4.7] synonym: "xanthine-dehydrogenase:glutathione-disulfide S-oxidoreductase activity" EXACT [EC:1.8.4.7] synonym: "xanthine-dehydrogenase:oxidized-glutathione S-oxidoreductase activity" EXACT [EC:1.8.4.7] xref: EC:1.8.4.7 xref: GO:0047142 xref: MetaCyc:1.8.4.7-RXN is_a: CCO:F0003264 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor [Term] id: CCO:F0006455 name: chlorate reductase activity namespace: molecular_function def: "Catalysis of the reaction: chlorate + donor-H2 = chlorite + H2O + acceptor." [EC:1.97.1.1, MetaCyc:1.97.1.1-RXN] subset: gosubset_prok synonym: "chlorate reductase C" RELATED [EC:1.97.1.1] synonym: "chlorite:acceptor oxidoreductase activity" EXACT [EC:1.97.1.1] xref: EC:1.97.1.1 xref: GO:0047143 xref: MetaCyc:1.97.1.1-RXN xref: UM-BBD_enzymeID:e0609 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0006456 name: 2-acylglycerol-3-phosphate O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA." [EC:2.3.1.52, MetaCyc:2-ACYL2.3.1.15-RXN] synonym: "2-acylglycerophosphate acyltransferase activity" EXACT [EC:2.3.1.52] synonym: "acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity" EXACT [EC:2.3.1.52] xref: EC:2.3.1.52 xref: GO:0047144 xref: MetaCyc:2-ACYL2.3.1.15-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006457 name: demethylsterigmatocystin 6-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine." [EC:2.1.1.109, MetaCyc:2.1.1.109-RXN] synonym: "demethylsterigmatocystin methyltransferase activity" EXACT [EC:2.1.1.109] synonym: "O-methyltransferase I" RELATED [EC:2.1.1.109] synonym: "S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity" EXACT [EC:2.1.1.109] xref: EC:2.1.1.109 xref: GO:0047145 xref: MetaCyc:2.1.1.109-RXN is_a: CCO:F0001758 ! O-methyltransferase activity [Term] id: CCO:F0006458 name: sterigmatocystin 7-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine." [EC:2.1.1.110, MetaCyc:2.1.1.110-RXN] synonym: "O-methyltransferase II activity" RELATED [EC:2.1.1.110] synonym: "S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase activity" EXACT [EC:2.1.1.110] synonym: "S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase activity" EXACT [EC:2.1.1.110] synonym: "sterigmatocystin 8-O-methyltransferase activity" EXACT [EC:2.1.1.110] synonym: "sterigmatocystin methyltransferase activity" EXACT [EC:2.1.1.110] xref: EC:2.1.1.110 xref: GO:0047146 xref: MetaCyc:2.1.1.110-RXN is_a: CCO:F0001758 ! O-methyltransferase activity [Term] id: CCO:F0006459 name: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: THF + trimethyl sulfonium = 5-methyl-THF + dimethyl sulfide." [EC:2.1.1.19, MetaCyc:2.1.1.19-RXN] synonym: "trimethylsulfonium-tetrahydrofolate methyltransferase activity" EXACT [EC:2.1.1.19] synonym: "trimethylsulfonium:tetrahydrofolate N-methyltransferase activity" EXACT [EC:2.1.1.19] synonym: "trimethylsulphonium-tetrahydrofolate N-methyltransferase activity" EXACT [] xref: EC:2.1.1.19 xref: GO:0047147 xref: MetaCyc:2.1.1.19-RXN is_a: CCO:F0001757 ! N-methyltransferase activity [Term] id: CCO:F0006460 name: methylamine-glutamate N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate + methylamine = N-methyl-L-glutamate + NH3." [EC:2.1.1.21, MetaCyc:2.1.1.21-RXN] synonym: "methylamine-glutamate methyltransferase activity" EXACT [EC:2.1.1.21] synonym: "methylamine:L-glutamate N-methyltransferase activity" EXACT [EC:2.1.1.21] synonym: "N-methylglutamate synthase activity" EXACT [EC:2.1.1.21] xref: EC:2.1.1.21 xref: GO:0047148 xref: MetaCyc:2.1.1.21-RXN is_a: CCO:F0001757 ! N-methyltransferase activity [Term] id: CCO:F0006461 name: thetin-homocysteine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: homocysteine + dimethylsulfonioacetate = L-methionine + S-methylthioglycolate." [EC:2.1.1.3, MetaCyc:2.1.1.3-RXN] synonym: "dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.3] synonym: "dimethylthetin-homocysteine methyltransferase activity" EXACT [EC:2.1.1.3] synonym: "thetin-homocysteine methylpherase activity" EXACT [EC:2.1.1.3] xref: EC:2.1.1.3 xref: GO:0047149 xref: MetaCyc:2.1.1.3-RXN is_a: CCO:F0001759 ! S-methyltransferase activity [Term] id: CCO:F0006462 name: betaine-homocysteine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: homocysteine + betaine = L-methionine + dimethylglycine." [EC:2.1.1.5, MetaCyc:2.1.1.5-RXN] synonym: "betaine-homocysteine methyltransferase activity" EXACT [EC:2.1.1.5] synonym: "betaine-homocysteine transmethylase activity" EXACT [EC:2.1.1.5] synonym: "trimethylammonioacetate:L-homocysteine S-methyltransferase activity" EXACT [EC:2.1.1.5] xref: EC:2.1.1.5 xref: GO:0047150 xref: MetaCyc:2.1.1.5-RXN is_a: CCO:F0001759 ! S-methyltransferase activity [Term] id: CCO:F0006463 name: methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity namespace: molecular_function def: "Catalysis of the reaction: FADH + H+ + tRNA U(psi)C = FAD+ + tRNA T(psi)C + THF." [EC:2.1.1.74, MetaCyc:2.1.1.74-RXN] synonym: "5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity" EXACT [EC:2.1.1.74] synonym: "5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity" EXACT [EC:2.1.1.74] synonym: "folate-dependent ribothymidyl synthase activity" EXACT [EC:2.1.1.74] synonym: "methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity" EXACT [EC:2.1.1.74] synonym: "methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity" EXACT [] xref: EC:2.1.1.74 xref: GO:0047151 xref: MetaCyc:2.1.1.74-RXN is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0006464 name: methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide." [EC:2.1.1.90, MetaCyc:2.1.1.90-RXN] comment: This function is the first step in the pathway of methanogenesis from methanol. subset: gosubset_prok synonym: "methanol cobalamin methyltransferase activity" EXACT [EC:2.1.1.90] synonym: "methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase activity" EXACT [EC:2.1.1.90] synonym: "methanol:5-hydroxybenzimidazolylcobamide methyltransferase activity" EXACT [EC:2.1.1.90] synonym: "methanol:corrinoid methyltransferase activity" EXACT [] synonym: "methyltransferase 1" BROAD [] synonym: "MT 1" RELATED [EC:2.1.1.90] synonym: "MT1" RELATED [] synonym: "MtaB" RELATED [] xref: EC:2.1.1.90 xref: GO:0047152 xref: MetaCyc:2.1.1.90-RXN is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0006465 name: deoxycytidylate 5-hydroxymethyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + H2O + deoxycytidylate = tetrahydrofolate + 5-hydroxymethyldeoxycytidylate." [EC:2.1.2.8, MetaCyc:2.1.2.8-RXN] synonym: "5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase activity" EXACT [EC:2.1.2.8] synonym: "d-cytidine 5'-monophosphate hydroxymethylase activity" EXACT [EC:2.1.2.8] synonym: "dCMP hydroxymethylase activity" EXACT [EC:2.1.2.8] synonym: "deoxyCMP hydroxymethylase activity" EXACT [EC:2.1.2.8] synonym: "deoxycytidylate hydroxymethylase activity" EXACT [EC:2.1.2.8] synonym: "deoxycytidylate hydroxymethyltransferase activity" EXACT [] synonym: "deoxycytidylic hydroxymethylase activity" EXACT [EC:2.1.2.8] xref: EC:2.1.2.8 xref: GO:0047153 xref: MetaCyc:2.1.2.8-RXN is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0006466 name: methylmalonyl-CoA carboxytransferase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA." [EC:2.1.3.1, MetaCyc:2.1.3.1-RXN] subset: gosubset_prok synonym: "(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate" RELATED [EC:2.1.3.1] synonym: "(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase activity" EXACT [EC:2.1.3.1] synonym: "(S)-methylmalonyl-CoA:pyruvate carboxyltransferase activity" EXACT [EC:2.1.3.1] synonym: "(S)-methylmalonyl-CoA:pyruvate carboxytransferase activity" EXACT [EC:2.1.3.1] synonym: "methylmalonyl coenzyme A carboxyltransferase activity" EXACT [EC:2.1.3.1] synonym: "methylmalonyl-CoA carboxyltransferase activity" EXACT [] synonym: "methylmalonyl-CoA transcarboxylase activity" EXACT [EC:2.1.3.1] synonym: "oxalacetic transcarboxylase activity" EXACT [EC:2.1.3.1] synonym: "transcarboxylase activity" RELATED [EC:2.1.3.1] xref: EC:2.1.3.1 xref: GO:0047154 xref: MetaCyc:2.1.3.1-RXN xref: UM-BBD_enzymeID:e0576 is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0006467 name: 3-hydroxymethylcephem carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem." [EC:2.1.3.7, MetaCyc:2.1.3.7-RXN] synonym: "3'-hydroxymethylcephem-O-carbamoyltransferase activity" EXACT [] synonym: "carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase activity" EXACT [EC:2.1.3.7] xref: EC:2.1.3.7 xref: GO:0045447 xref: GO:0047155 xref: MetaCyc:2.1.3.7-RXN is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0006468 name: acetoin-ribose-5-phosphate transaldolase activity namespace: molecular_function def: "Catalysis of the reaction: ribose-5-phosphate + 3-hydroxybutan-2-one = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde." [EC:2.2.1.4, MetaCyc:2.2.1.4-RXN] synonym: "1-deoxy-D-altro-heptulose-7-phosphate synthase activity" EXACT [EC:2.2.1.4] synonym: "1-deoxy-D-altro-heptulose-7-phosphate synthetase activity" EXACT [EC:2.2.1.4] synonym: "3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase activity" EXACT [EC:2.2.1.4] synonym: "3-hydroxybutan-3-one:D-ribose-5-phosphate aldehydetransferase activity" EXACT [EC:2.2.1.4] xref: EC:2.2.1.4 xref: GO:0047156 xref: MetaCyc:2.2.1.4-RXN is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0006469 name: myelin-proteolipid O-palmitoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA." [EC:2.3.1.100, MetaCyc:2.3.1.100-RXN] synonym: "[myelin-proteolipid] O-palmitoyltransferase activity" EXACT [EC:2.3.1.100] synonym: "acyl-protein synthase activity" BROAD [EC:2.3.1.100] synonym: "myelin PLP acyltransferase activity" EXACT [EC:2.3.1.100] synonym: "palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase activity" EXACT [EC:2.3.1.100] xref: EC:2.3.1.100 xref: GO:0047157 xref: MetaCyc:2.3.1.100-RXN is_a: CCO:F0003139 ! O-palmitoyltransferase activity [Term] id: CCO:F0006470 name: sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucoside = 1,2-bis-O-sinapoyl beta-D-glucoside + beta-D-glucose." [EC:2.3.1.103, MetaCyc:2.3.1.103-RXN] synonym: "1-(hydroxycinnamoyl)-glucose:1-(hydroxycinnamoyl)-glucose hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.103] synonym: "1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase activity" EXACT [EC:2.3.1.103] synonym: "hydroxycinnamoylglucose-hydroxycinnamoylglucose hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.103] xref: EC:2.3.1.103 xref: GO:0047158 xref: MetaCyc:2.3.1.103-RXN is_a: CCO:F0003328 ! O-sinapoyltransferase activity [Term] id: CCO:F0006471 name: 1-alkenylglycerophosphocholine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA." [EC:2.3.1.104, MetaCyc:2.3.1.104-RXN] synonym: "acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.104] xref: EC:2.3.1.104 xref: GO:0047159 xref: MetaCyc:2.3.1.104-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006472 name: alkylglycerophosphate 2-O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA." [EC:2.3.1.105, MetaCyc:2.3.1.105-RXN] synonym: "acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase activity" EXACT [EC:2.3.1.105] synonym: "alkyllyso-GP:acetyl-CoA acetyltransferase activity" EXACT [EC:2.3.1.105] xref: EC:2.3.1.105 xref: GO:0047160 xref: MetaCyc:2.3.1.105-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006473 name: tartronate O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxymalonate + sinapoyl-CoA = sinapoyltartronate + CoA." [EC:2.3.1.106, MetaCyc:2.3.1.106-RXN] synonym: "hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.106] synonym: "sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.106] synonym: "tartronate sinapoyltransferase activity" EXACT [EC:2.3.1.106] xref: EC:2.3.1.106 xref: GO:0047161 xref: MetaCyc:2.3.1.106-RXN is_a: CCO:F0008005 ! O-hydroxycinnamoyltransferase activity [Term] id: CCO:F0006474 name: 17-O-deacetylvindoline O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 17-O-deacetylvindoline + acetyl-CoA = vindoline + CoA." [EC:2.3.1.107, MetaCyc:2.3.1.107-RXN] synonym: "17-O-deacetylvindoline-17-O-acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "acetyl-CoA:deacetylvindoline 4-O-acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "acetylcoenzyme A:deacetylvindoline O-acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "DAT activity" EXACT [EC:2.3.1.107] synonym: "deacetylvindoline acetyltransferase activity" EXACT [EC:2.3.1.107] synonym: "deacetylvindoline O-acetyltransferase activity" EXACT [EC:2.3.1.107] xref: EC:2.3.1.107 xref: GO:0047162 xref: MetaCyc:2.3.1.107-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006475 name: 3,4-dichloroaniline N-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonate + CoA." [EC:2.3.1.114, MetaCyc:2.3.1.114-RXN] synonym: "malonyl-CoA:3,4-dichloroaniline N-malonyltransferase activity" EXACT [EC:2.3.1.114] xref: EC:2.3.1.114 xref: GO:0047163 xref: MetaCyc:2.3.1.114-RXN is_a: CCO:F0008003 ! N-malonyltransferase activity [Term] id: CCO:F0006476 name: isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA." [EC:2.3.1.115, MetaCyc:2.3.1.115-RXN] synonym: "flavone (flavonol) 7-O-glycoside malonyltransferase activity" EXACT [EC:2.3.1.115] synonym: "flavone/flavonol 7-O-beta-D-glucoside malonyltransferase activity" EXACT [EC:2.3.1.115] synonym: "malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase activity" EXACT [EC:2.3.1.115] synonym: "malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.115] synonym: "malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase activity" EXACT [EC:2.3.1.115] synonym: "malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase activity" EXACT [EC:2.3.1.115] synonym: "MAT-7" RELATED [EC:2.3.1.115] xref: EC:2.3.1.115 xref: GO:0047164 xref: MetaCyc:2.3.1.115-RXN is_a: CCO:F0008004 ! O-malonyltransferase activity [Term] id: CCO:F0006477 name: flavonol-3-O-beta-glucoside O-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA." [EC:2.3.1.116, MetaCyc:2.3.1.116-RXN] synonym: "flavonol 3-O-glucoside malonyltransferase activity" EXACT [EC:2.3.1.116] synonym: "malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase activity" EXACT [EC:2.3.1.116] synonym: "malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase activity" EXACT [EC:2.3.1.116] synonym: "MAT-3" RELATED [EC:2.3.1.116] xref: EC:2.3.1.116 xref: GO:0047165 xref: MetaCyc:2.3.1.116-RXN is_a: CCO:F0008004 ! O-malonyltransferase activity [Term] id: CCO:F0006478 name: 1-alkenylglycerophosphoethanolamine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA." [EC:2.3.1.121, MetaCyc:2.3.1.121-RXN] synonym: "acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase activity" EXACT [EC:2.3.1.121] xref: EC:2.3.1.121 xref: GO:0047166 xref: MetaCyc:2.3.1.121-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006479 name: 1-alkyl-2-acetylglycerol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA." [EC:2.3.1.125, MetaCyc:2.3.1.125-RXN] synonym: "1-hexadecyl-2-acetylglycerol acyltransferase activity" EXACT [EC:2.3.1.125] synonym: "acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase activity" EXACT [EC:2.3.1.125] xref: EC:2.3.1.125 xref: GO:0047167 xref: MetaCyc:2.3.1.125-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006480 name: isocitrate O-dihydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: threo-d(s)-iso-citrate + caffeoyl-CoA = 2-caffeoylisocitrate + CoA." [EC:2.3.1.126, MetaCyc:2.3.1.126-RXN] synonym: "caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.126] xref: EC:2.3.1.126 xref: GO:0047168 xref: MetaCyc:2.3.1.126-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006481 name: galactarate O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: feruloyl-CoA + D-galactarate = O-feruloylgalactarate + CoA." [EC:2.3.1.130, MetaCyc:2.3.1.130-RXN] synonym: "feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.130] synonym: "galacturate hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.130] xref: EC:2.3.1.130 xref: GO:0047169 xref: MetaCyc:2.3.1.130-RXN is_a: CCO:F0008005 ! O-hydroxycinnamoyltransferase activity [Term] id: CCO:F0006482 name: glucarate O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucarate + sinapoyl-CoA = O-sinapoylglucarate + CoA." [EC:2.3.1.131, MetaCyc:2.3.1.131-RXN] synonym: "sinapoyl-CoA:glucarate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.131] xref: EC:2.3.1.131 xref: GO:0047170 xref: MetaCyc:2.3.1.131-RXN is_a: CCO:F0008005 ! O-hydroxycinnamoyltransferase activity [Term] id: CCO:F0006483 name: glucarolactone O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA." [EC:2.3.1.132, MetaCyc:2.3.1.132-RXN] synonym: "sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.132] xref: EC:2.3.1.132 xref: GO:0047171 xref: MetaCyc:2.3.1.132-RXN is_a: CCO:F0008005 ! O-hydroxycinnamoyltransferase activity [Term] id: CCO:F0006484 name: shikimate O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA." [EC:2.3.1.133, MetaCyc:2.3.1.133-RXN] synonym: "4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.133] synonym: "shikimate hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.133] xref: EC:2.3.1.133 xref: GO:0047172 xref: MetaCyc:2.3.1.133-RXN is_a: CCO:F0008005 ! O-hydroxycinnamoyltransferase activity [Term] id: CCO:F0006485 name: phosphatidylcholine-retinol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine." [EC:2.3.1.135, MetaCyc:2.3.1.135-RXN] synonym: "lecithin--retinol acyltransferase activity" EXACT [EC:2.3.1.135] synonym: "phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity" EXACT [EC:2.3.1.135] synonym: "phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity" EXACT [EC:2.3.1.135] xref: EC:2.3.1.135 xref: GO:0047173 xref: MetaCyc:2.3.1.135-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006486 name: putrescine N-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: putrescine + caffeoyl-CoA = N-caffeoylputrescine + CoA." [EC:2.3.1.138, MetaCyc:2.3.1.138-RXN] synonym: "caffeoyl-CoA putrescine N-caffeoyl transferase activity" EXACT [EC:2.3.1.138] synonym: "caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.138] synonym: "hydroxycinnamoyl-CoA:putrescine hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.138] synonym: "PHT" RELATED [EC:2.3.1.138] synonym: "putrescine hydroxycinnamoyl transferase activity" EXACT [EC:2.3.1.138] synonym: "putrescine hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.138] xref: EC:2.3.1.138 xref: GO:0047174 xref: MetaCyc:2.3.1.138-RXN is_a: CCO:F0003133 ! N-acyltransferase activity is_a: CCO:F0008002 ! hydroxycinnamoyltransferase activity [Term] id: CCO:F0006487 name: galactosylacylglycerol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein]." [EC:2.3.1.141, MetaCyc:2.3.1.141-RXN] synonym: "acyl-ACP:lyso-MGDG acyltransferase activity" EXACT [EC:2.3.1.141] synonym: "acyl-acyl-carrier protein: lysomonogalactosyldiacylglycerol acyltransferase activity" EXACT [EC:2.3.1.141] synonym: "acyl-acyl-carrier-protein:D-galactosylacylglycerol O-acyltransferase activity" EXACT [EC:2.3.1.141] xref: EC:2.3.1.141 xref: GO:0047175 xref: MetaCyc:2.3.1.141-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006488 name: beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + beta-D-glucose." [EC:2.3.1.143, MetaCyc:2.3.1.143-RXN] synonym: "1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity" EXACT [EC:2.3.1.143] synonym: "beta-glucogallin-tetragalloylglucose 4-galloyltransferase activity" EXACT [EC:2.3.1.143] synonym: "beta-glucogallin:1,2,3,6-tetra-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity" EXACT [EC:2.3.1.143] synonym: "beta-glucogallin:1,2,3,6-tetra-O-galloylglucose 4-O-galloyltransferase activity" EXACT [EC:2.3.1.143] xref: EC:2.3.1.143 xref: GO:0047176 xref: MetaCyc:2.3.1.143-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006489 name: glycerophospholipid arachidonoyl-transferase (CoA-independent) activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine." [EC:2.3.1.147, MetaCyc:2.3.1.147-RXN] synonym: "1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)" EXACT [EC:2.3.1.147] synonym: "1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)" EXACT [EC:2.3.1.147] xref: EC:2.3.1.147 xref: GO:0047177 xref: MetaCyc:2.3.1.147-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006490 name: glycerophospholipid acyltransferase (CoA-dependent) activity namespace: molecular_function def: "Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine." [EC:2.3.1.148, MetaCyc:2.3.1.148-RXN] synonym: "1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent)" EXACT [EC:2.3.1.148] xref: EC:2.3.1.148 xref: GO:0047178 xref: MetaCyc:2.3.1.148-RXN is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0006491 name: platelet-activating factor acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid." [EC:2.3.1.149, MetaCyc:2.3.1.149-RXN] synonym: "1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase activity" EXACT [EC:2.3.1.149] synonym: "PAF acetyltransferase activity" EXACT [] xref: EC:2.3.1.149 xref: GO:0047179 xref: MetaCyc:2.3.1.149-RXN is_a: CCO:F0003130 ! acetyltransferase activity [Term] id: CCO:F0006492 name: salutaridinol 7-O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: salutaridinol + acetyl-CoA = 7-O-acetylsalutaridinol + CoA." [EC:2.3.1.150, MetaCyc:2.3.1.150-RXN] synonym: "acetyl-CoA:salutaridinol 7-O-acetyltransferase activity" EXACT [EC:2.3.1.150] xref: EC:2.3.1.150 xref: GO:0047180 xref: MetaCyc:2.3.1.150-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006493 name: benzophenone synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A." [EC:2.3.1.151, MetaCyc:2.3.1.151-RXN] synonym: "malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase activity" EXACT [EC:2.3.1.151] xref: EC:2.3.1.151 xref: GO:0047181 xref: MetaCyc:2.3.1.151-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006494 name: alcohol O-cinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate." [EC:2.3.1.152, MetaCyc:2.3.1.152-RXN] synonym: "1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase activity" EXACT [EC:2.3.1.152] xref: EC:2.3.1.152 xref: GO:0047182 xref: MetaCyc:2.3.1.152-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006495 name: anthocyanin 5-aromatic acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA." [EC:2.3.1.153, MetaCyc:2.3.1.153-RXN] synonym: "hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase activity" EXACT [EC:2.3.1.153] xref: EC:2.3.1.153 xref: GO:0047183 xref: MetaCyc:2.3.1.153-RXN is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0006496 name: 1-acylglycerophosphocholine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA." [EC:2.3.1.23, MetaCyc:2.3.1.23-RXN] synonym: "1-acyl-sn-glycero-3-phosphocholine acyltransferase activity" EXACT [EC:2.3.1.23] synonym: "acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity" EXACT [EC:2.3.1.23] synonym: "acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase activity" EXACT [EC:2.3.1.23] synonym: "acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.23] synonym: "lysolecithin acyltransferase activity" EXACT [EC:2.3.1.23] synonym: "lysophosphatide acyltransferase activity" EXACT [EC:2.3.1.23] synonym: "lysophosphatidylcholine acyltransferase activity" EXACT [EC:2.3.1.23] xref: EC:2.3.1.23 xref: GO:0000507 xref: GO:0047184 xref: MetaCyc:2.3.1.23-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006497 name: N-acetylneuraminate 4-O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA." [EC:2.3.1.44, MetaCyc:2.3.1.44-RXN] synonym: "acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity" EXACT [EC:2.3.1.44] synonym: "sialate O-acetyltransferase" BROAD [EC:2.3.1.44] xref: EC:2.3.1.44 xref: GO:0047185 xref: MetaCyc:2.3.1.44-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006498 name: N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA." [EC:2.3.1.45, MetaCyc:2.3.1.45-RXN] synonym: "acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "glycoprotein 7(9)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "N-acetylneuraminate 7(8)-O-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "N-acetylneuraminate 7,8-O-acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "N-acetylneuraminate O7-(or O9-)acetyltransferase activity" EXACT [EC:2.3.1.45] synonym: "sialate O-acetyltransferase" BROAD [EC:2.3.1.45] xref: EC:2.3.1.45 xref: GO:0047186 xref: MetaCyc:2.3.1.45-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006499 name: deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate." [EC:2.3.1.49, MetaCyc:2.3.1.49-RXN] synonym: "deacetyl-citrate-(pro-3S)-lyase acetyltransferase activity" EXACT [EC:2.3.1.49] synonym: "deacetyl-citrate-(pro-3S)-lyase S-acetyltransferase activity" EXACT [EC:2.3.1.49] synonym: "S-acetyl phosphopantetheine:deacetyl citrate lyase S-acetyltransferase activity" EXACT [EC:2.3.1.49] synonym: "S-acetylphosphopantetheine:deacetyl-citrate-oxaloacetate-lyase((pro-3S)-CH2COO-rightacetate)S-acetyltransferase activity" EXACT [EC:2.3.1.49] xref: EC:2.3.1.49 xref: GO:0047187 xref: MetaCyc:2.3.1.49-RXN is_a: CCO:F0003141 ! S-acetyltransferase activity [Term] id: CCO:F0006500 name: aromatic-hydroxylamine O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl." [EC:2.3.1.56, MetaCyc:2.3.1.56-RXN] synonym: "aromatic hydroxylamine acetyltransferase activity" EXACT [EC:2.3.1.56] synonym: "arylhydroxamate acyltransferase activity" EXACT [EC:2.3.1.56] synonym: "arylhydroxamic acid N,O-acetyltransferase activity" EXACT [EC:2.3.1.56] synonym: "arylhydroxamic acyltransferase activity" EXACT [EC:2.3.1.56] synonym: "N,O-acetyltransferase activity" EXACT [EC:2.3.1.56] synonym: "N-hydroxy-2-acetylaminofluorene N-O acyltransferase activity" EXACT [EC:2.3.1.56] synonym: "N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase activity" EXACT [EC:2.3.1.56] xref: EC:2.3.1.56 xref: GO:0047188 xref: MetaCyc:2.3.1.56-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006501 name: 2,3-diaminopropionate N-oxalyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-2,3-diaminopropanoate + oxalyl-CoA = N3-oxalyl-L-23-diaminopropanoate + CoA." [EC:2.3.1.58, MetaCyc:2.3.1.58-RXN] synonym: "ODAP synthase activity" EXACT [EC:2.3.1.58] synonym: "oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase activity" EXACT [EC:2.3.1.58] synonym: "oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase activity" EXACT [EC:2.3.1.58] synonym: "oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase activity" EXACT [EC:2.3.1.58] synonym: "oxalyldiaminopropionate synthase activity" EXACT [EC:2.3.1.58] synonym: "oxalyldiaminopropionic synthase activity" EXACT [EC:2.3.1.58] xref: EC:2.3.1.58 xref: GO:0047189 xref: MetaCyc:2.3.1.58-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006502 name: 2-acylglycerophosphocholine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA." [EC:2.3.1.62, MetaCyc:2.3.1.62-RXN] synonym: "2-acylglycerol-3-phosphorylcholine acyltransferase activity" EXACT [EC:2.3.1.62] synonym: "2-acylglycerophosphocholine acyltransferase activity" EXACT [EC:2.3.1.62] synonym: "acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.62] xref: EC:2.3.1.62 xref: GO:0047190 xref: MetaCyc:2.3.1.62-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006503 name: 1-alkylglycerophosphocholine O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA." [EC:2.3.1.63, MetaCyc:2.3.1.63-RXN] synonym: "acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase activity" EXACT [EC:2.3.1.63] xref: EC:2.3.1.63 xref: GO:0047191 xref: MetaCyc:2.3.1.63-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006504 name: 1-alkylglycerophosphocholine O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA." [EC:2.3.1.67, MetaCyc:2.3.1.67-RXN] synonym: "1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity" EXACT [EC:2.3.1.67] synonym: "1-alkyl-2-lysolecithin acetyltransferase activity" EXACT [EC:2.3.1.67] synonym: "acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity" EXACT [EC:2.3.1.67] synonym: "acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity" EXACT [EC:2.3.1.67] synonym: "acetyl-CoA:lyso-PAF acetyltransferase activity" EXACT [EC:2.3.1.67] synonym: "acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity" EXACT [EC:2.3.1.67] synonym: "blood platelet-activating factor acetyltransferase activity" BROAD [EC:2.3.1.67] synonym: "lyso-GPC:acetyl CoA acetyltransferase activity" BROAD [EC:2.3.1.67] synonym: "lyso-platelet activating factor:acetyl-CoA acetyltransferase activity" BROAD [EC:2.3.1.67] synonym: "lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity" BROAD [EC:2.3.1.67] synonym: "lysoPAF:acetyl CoA acetyltransferase activity" EXACT [EC:2.3.1.67] synonym: "lysopaf:acetyl CoA acetyltransferase activity" BROAD [EC:2.3.1.67] synonym: "platelet-activating factor acylhydrolase activity" BROAD [EC:2.3.1.67] synonym: "platelet-activating factor-synthesizing enzyme activity" BROAD [EC:2.3.1.67] xref: EC:2.3.1.67 xref: GO:0047192 xref: MetaCyc:2.3.1.67-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0006505 name: CDP-acylglycerol O-arachidonoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA." [EC:2.3.1.70, MetaCyc:2.3.1.70-RXN] synonym: "arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase activity" EXACT [EC:2.3.1.70] synonym: "arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase activity" EXACT [EC:2.3.1.70] synonym: "CDP-acylglycerol O-arachidonyltransferase activity" EXACT [] synonym: "CDPacylglycerol O-arachidonyltransferase activity" EXACT [EC:2.3.1.70] xref: EC:2.3.1.70 xref: GO:0047193 xref: MetaCyc:2.3.1.70-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006506 name: indoleacetylglucose-inositol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol + indole-3-acetyl-beta-1-D-glucose = indole-3-acetyl-myo-inositol + beta-D-glucose." [EC:2.3.1.72, MetaCyc:2.3.1.72-RXN] synonym: "1-O-(indol-3-yl)acetyl-beta-D-glucose:myo-inositol (indol-3-yl)acetyltransferase activity" EXACT [EC:2.3.1.72] synonym: "1-O-(indol-3-ylacetyl)-beta-D-glucose:myo-inositol indole-3-ylacetyltransferase activity" EXACT [EC:2.3.1.72] synonym: "indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase activity" EXACT [EC:2.3.1.72] xref: EC:2.3.1.72 xref: GO:0047194 xref: MetaCyc:2.3.1.72-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006507 name: diacylglycerol-sterol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol." [EC:2.3.1.73, MetaCyc:2.3.1.73-RXN] synonym: "1,2-diacyl-sn-glycerol:sterol acyl transferase activity" EXACT [EC:2.3.1.73] synonym: "1,2-diacyl-sn-glycerol:sterol O-acyltransferase activity" EXACT [EC:2.3.1.73] xref: EC:2.3.1.73 xref: GO:0047195 xref: MetaCyc:2.3.1.73-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006508 name: long-chain-alcohol O-fatty-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA." [EC:2.3.1.75, MetaCyc:2.3.1.75-RXN] synonym: "acyl-CoA:long-chain-alcohol O-acyltransferase activity" EXACT [EC:2.3.1.75] synonym: "wax synthase activity" RELATED [EC:2.3.1.75] synonym: "wax-ester synthase activity" EXACT [EC:2.3.1.75] xref: EC:2.3.1.75 xref: GO:0047196 xref: MetaCyc:2.3.1.75-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006509 name: triacylglycerol-sterol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol." [EC:2.3.1.77, MetaCyc:2.3.1.77-RXN] synonym: "triacylglycerol:3beta-hydroxysterol O-acyltransferase activity" EXACT [EC:2.3.1.77] synonym: "triacylglycerol:sterol acyltransferase activity" EXACT [EC:2.3.1.77] xref: EC:2.3.1.77 xref: GO:0047197 xref: MetaCyc:2.3.1.77-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006510 name: cysteine-S-conjugate N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: an S-substituted L-cysteine + acetyl-CoA = an S-substituted N-acetyl-L-cysteine + CoA." [EC:2.3.1.80, MetaCyc:2.3.1.80-RXN] synonym: "acetyl-CoA:S-substituted L-cysteine N-acetyltransferase activity" EXACT [EC:2.3.1.80] xref: EC:2.3.1.80 xref: GO:0047198 xref: MetaCyc:2.3.1.80-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0006511 name: phosphatidylcholine-dolichol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dolichol + phosphatidylcholine = acyldolichol + 1-acyl-sn-glycero-3-phosphocholine." [EC:2.3.1.83, MetaCyc:2.3.1.83-RXN] synonym: "3-sn-phosphatidylcholine:dolichol O-acyltransferase activity" EXACT [EC:2.3.1.83] xref: EC:2.3.1.83 xref: GO:0047199 xref: MetaCyc:2.3.1.83-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0006512 name: tetrahydrodipicolinate N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA = L-2-acetamido-6-oxoheptanedioate + CoA." [EC:2.3.1.89, MetaCyc:2.3.1.89-RXN] subset: gosubset_prok synonym: "acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity" EXACT [EC:2.3.1.89] synonym: "acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity" EXACT [EC:2.3.1.89] synonym: "acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity" EXACT [EC:2.3.1.89] synonym: "tetrahydrodipicolinate acetylase activity" EXACT [EC:2.3.1.89] synonym: "tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity" EXACT [EC:2.3.1.89] xref: EC:2.3.1.89 xref: GO:0047200 xref: MetaCyc:2.3.1.89-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0006513 name: beta-glucogallin O-galloyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1-O,6-O-digalloyl-beta-D-glucose + beta-D-glucose." [EC:2.3.1.90, MetaCyc:2.3.1.90-RXN] synonym: "1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase activity" EXACT [EC:2.3.1.90] xref: EC:2.3.1.90 xref: GO:0047201 xref: MetaCyc:2.3.1.90-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006514 name: sinapoylglucose-choline O-sinapoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: choline + 1-O-sinapoyl-beta-D-glucose = O-sinapoylcholine + beta-D-glucose." [EC:2.3.1.91, MetaCyc:2.3.1.91-RXN] synonym: "1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase activity" EXACT [EC:2.3.1.91] synonym: "sinapine synthase activity" EXACT [EC:2.3.1.91] xref: EC:2.3.1.91 xref: GO:0047202 xref: MetaCyc:2.3.1.91-RXN is_a: CCO:F0003328 ! O-sinapoyltransferase activity [Term] id: CCO:F0006515 name: 13-hydroxylupinine O-tigloyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 13-hydroxylupinine + (E)-2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyl)oxylupinine + CoA." [EC:2.3.1.93, MetaCyc:2.3.1.93-RXN] synonym: "(E)-2-methylcrotonoyl-CoA:13-hydroxylupinine O-2-methylcrotonoyltransferase activity" EXACT [EC:2.3.1.93] synonym: "13-hydroxylupanine acyltransferase activity" EXACT [EC:2.3.1.93] synonym: "tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase activity" EXACT [EC:2.3.1.93] xref: EC:2.3.1.93 xref: GO:0047203 xref: MetaCyc:2.3.1.93-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006516 name: chlorogenate-glucarate O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucarate + chlorogenate = 2-O-caffeoylglucarate + quinate." [EC:2.3.1.98, MetaCyc:2.3.1.98-RXN] synonym: "chlorogenate:glucarate caffeoyltransferase activity" EXACT [EC:2.3.1.98] synonym: "chlorogenate:glucarate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.98] synonym: "chlorogenic acid:glucaric acid O-caffeoyltransferase activity" EXACT [EC:2.3.1.98] xref: EC:2.3.1.98 xref: GO:0047204 xref: MetaCyc:2.3.1.98-RXN is_a: CCO:F0008005 ! O-hydroxycinnamoyltransferase activity [Term] id: CCO:F0006517 name: quinate O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA." [EC:2.3.1.99, MetaCyc:2.3.1.99-RXN] synonym: "feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.99] synonym: "hydroxycinnamoyl coenzyme A-quinate transferase activity" EXACT [EC:2.3.1.99] xref: EC:2.3.1.99 xref: GO:0047205 xref: MetaCyc:2.3.1.99-RXN is_a: CCO:F0008005 ! O-hydroxycinnamoyltransferase activity [Term] id: CCO:F0006518 name: UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA." [EC:2.3.2.10, MetaCyc:2.3.2.10-RXN] synonym: "alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase activity" EXACT [EC:2.3.2.10] synonym: "L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase activity" EXACT [EC:2.3.2.10] synonym: "L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase activity" EXACT [EC:2.3.2.10] synonym: "UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity" EXACT [EC:2.3.2.10] synonym: "UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase activity" EXACT [EC:2.3.2.10] synonym: "uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity" EXACT [EC:2.3.2.10] synonym: "uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase activity" EXACT [EC:2.3.2.10] xref: EC:2.3.2.10 xref: GO:0047206 xref: MetaCyc:2.3.2.10-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0006519 name: 1,2-beta-fructan 1F-fructosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (1,2-beta-D-fructosyl)(n) + (1,2-beta-D-fructosyl)(m) = (1,2-beta-D-fructosyl)(n+1) + (1,2-beta-D-fructosyl)(m-1)." [EC:2.4.1.100, MetaCyc:2.4.1.100-RXN] synonym: "1,2-beta-D-fructan 1(F)-fructosyltransferase activity" EXACT [EC:2.4.1.100] synonym: "1,2-beta-D-fructan 1F-fructosyltransferase activity" EXACT [EC:2.4.1.100] synonym: "1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.100] synonym: "1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.100] synonym: "1,2-beta-fructan 1(F)-fructosyltransferase activity" EXACT [EC:2.4.1.100] synonym: "2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.100] synonym: "2,1-fructan:2,1-fructan 1-fructosyltransferase activity" EXACT [EC:2.4.1.100] synonym: "FFT activity" EXACT [EC:2.4.1.100] synonym: "fructan:fructan fructosyl transferase activity" EXACT [EC:2.4.1.100] xref: EC:2.4.1.100 xref: GO:0047207 xref: MetaCyc:2.4.1.100-RXN is_a: CCO:F0008006 ! fructosyltransferase activity [Term] id: CCO:F0006520 name: o-dihydroxycoumarin 7-O-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + UDP." [EC:2.4.1.104, MetaCyc:2.4.1.104-RXN] synonym: "UDP-glucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.104] synonym: "UDP-glucose:o-dihydroxycoumarin glucosyltransferase activity" EXACT [EC:2.4.1.104] synonym: "UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.104] synonym: "uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.104] xref: EC:2.4.1.104 xref: GO:0047208 xref: MetaCyc:2.4.1.104-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006521 name: coniferyl-alcohol glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP." [EC:2.4.1.111, MetaCyc:2.4.1.111-RXN] synonym: "UDP-glucose coniferyl alcohol glucosyltransferase activity" EXACT [EC:2.4.1.111] synonym: "UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.111] synonym: "UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.111] synonym: "uridine diphosphoglucose-coniferyl alcohol glucosyltransferase activity" EXACT [EC:2.4.1.111] xref: EC:2.4.1.111 xref: GO:0047209 xref: MetaCyc:2.4.1.111-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006522 name: alpha-1,4-glucan-protein synthase (UDP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: protein + UDP-D-glucose = alpha-D-glucosyl-protein + UDP." [EC:2.4.1.112, MetaCyc:2.4.1.112-RXN] synonym: "1,4alpha-glucan-protein synthase (UDP-forming) activity" EXACT [] xref: EC:2.4.1.112 xref: GO:0047210 xref: MetaCyc:2.4.1.112-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006523 name: alpha-1,4-glucan-protein synthase (ADP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP." [EC:2.4.1.113, MetaCyc:2.4.1.113-RXN] synonym: "1,4alpha-glucan-protein synthase (ADP-forming) activity" EXACT [] synonym: "adenosine diphosphoglucose-protein glucosyltransferase activity" EXACT [EC:2.4.1.113] synonym: "ADP-glucose:protein 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.113] synonym: "ADPglucose:protein 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.113] synonym: "ADPglucose:protein glucosyltransferase activity" EXACT [EC:2.4.1.113] xref: EC:2.4.1.113 xref: GO:0047211 xref: MetaCyc:2.4.1.113-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006524 name: 2-coumarate O-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + UDP." [EC:2.4.1.114, MetaCyc:2.4.1.114-RXN] synonym: "UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.114] synonym: "UDPG:o-coumaric acid O-glucosyltransferase activity" EXACT [EC:2.4.1.114] synonym: "UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.114] synonym: "uridine diphosphoglucose-o-coumarate glucosyltransferase activity" EXACT [EC:2.4.1.114] xref: EC:2.4.1.114 xref: GO:0047212 xref: MetaCyc:2.4.1.114-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006525 name: anthocyanidin 3-O-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP." [EC:2.4.1.115, MetaCyc:2.4.1.115-RXN] synonym: "3-GT activity" EXACT [EC:2.4.1.115] synonym: "UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.115] synonym: "UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.115] synonym: "UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.115] synonym: "UDP-glucose:cyanidin-3-O-glucosyltransferase activity" EXACT [EC:2.4.1.115] synonym: "uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.115] xref: EC:2.4.1.115 xref: GO:0047213 xref: MetaCyc:2.4.1.115-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006526 name: cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP." [EC:2.4.1.116, MetaCyc:2.4.1.116-RXN] synonym: "cyanidin-3-O-rutinoside 5-O-glucosyltransferase activity" EXACT [EC:2.4.1.116] synonym: "UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.116] synonym: "UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside 5-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.116] synonym: "uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase activity" EXACT [EC:2.4.1.116] xref: EC:2.4.1.116 xref: GO:0047214 xref: MetaCyc:2.4.1.116-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006527 name: indole-3-acetate beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: auxin + UDP-D-glucose = indole-3-acetyl-beta-1-D-glucose + UDP." [EC:2.4.1.121, MetaCyc:2.4.1.121-RXN] synonym: "IAA-Glu synthetase activity" EXACT [EC:2.4.1.121] synonym: "IAA-glucose synthase activity" EXACT [EC:2.4.1.121] synonym: "IAGlu synthase activity" EXACT [EC:2.4.1.121] synonym: "indol-3-ylacetylglucose synthase activity" EXACT [EC:2.4.1.121] synonym: "UDP-glucose:(indol-3-yl)acetate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.121] synonym: "UDP-glucose:indol-3-ylacetate glucosyl-transferase activity" EXACT [EC:2.4.1.121] synonym: "UDP-glucose:indol-3-ylacetate glucosyltransferase activity" EXACT [EC:2.4.1.121] synonym: "UDPG-indol-3-ylacetyl glucosyl transferase activity" EXACT [EC:2.4.1.121] synonym: "UDPglucose:indole-3-acetate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.121] synonym: "uridine diphosphoglucose-indoleacetate glucosyltransferase activity" EXACT [EC:2.4.1.121] xref: EC:2.4.1.121 xref: GO:0047215 xref: MetaCyc:2.4.1.121-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006528 name: inositol 3-alpha-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP." [EC:2.4.1.123, MetaCyc:2.4.1.123-RXN] synonym: "galactinol synthase activity" EXACT [EC:2.4.1.123] synonym: "inositol 1-alpha-galactosyltransferase activity" EXACT [] synonym: "UDP-D-galactose:inositol galactosyltransferase activity" EXACT [EC:2.4.1.123] synonym: "UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.123] synonym: "UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.123] synonym: "UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.123] synonym: "uridine diphosphogalactose-inositol galactosyltransferase activity" EXACT [EC:2.4.1.123] xref: EC:2.4.1.123 xref: GO:0047216 xref: MetaCyc:2.4.1.123-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006529 name: sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose." [EC:2.4.1.125, MetaCyc:2.4.1.125-RXN] synonym: "GTF-S" RELATED [EC:2.4.1.125] synonym: "sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase" BROAD [EC:2.4.1.125] synonym: "sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.125] synonym: "sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase activity" EXACT [EC:2.4.1.125] synonym: "water-soluble-glucan synthase activity" RELATED [EC:2.4.1.125] xref: EC:2.4.1.125 xref: GO:0047217 xref: MetaCyc:2.4.1.125-RXN is_a: CCO:F0006200 ! glucosyltransferase activity [Term] id: CCO:F0006530 name: hydroxycinnamate 4-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP." [EC:2.4.1.126, MetaCyc:2.4.1.126-RXN] synonym: "hydroxycinnamoyl glucosyltransferase activity" EXACT [EC:2.4.1.126] synonym: "UDP-glucose-hydroxycinnamate glucosyltransferase activity" EXACT [EC:2.4.1.126] synonym: "UDP-glucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.126] synonym: "UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.126] synonym: "uridine diphosphoglucose-hydroxycinnamate glucosyltransferase activity" EXACT [EC:2.4.1.126] xref: EC:2.4.1.126 xref: GO:0047218 xref: MetaCyc:2.4.1.126-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006531 name: monoterpenol beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl O-beta-D-glucoside + UDP." [EC:2.4.1.127, MetaCyc:2.4.1.127-RXN] synonym: "UDP-glucose:(-)-menthol O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.127] synonym: "UDPglucose:(-)-menthol O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.127] synonym: "UDPglucose:monoterpenol glucosyltransferase activity" EXACT [EC:2.4.1.127] synonym: "uridine diphosphoglucose-monoterpenol glucosyltransferase activity" EXACT [EC:2.4.1.127] xref: EC:2.4.1.127 xref: GO:0047219 xref: MetaCyc:2.4.1.127-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006532 name: galactosylxylosylprotein 3-beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP." [EC:2.4.1.134, MetaCyc:2.4.1.134-RXN] synonym: "galactosyltransferase II activity" RELATED [EC:2.4.1.134] synonym: "UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.134] synonym: "UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.134] synonym: "uridine diphosphogalactose-galactosylxylose galactosyltransferase activity" EXACT [EC:2.4.1.134] xref: EC:2.4.1.134 xref: GO:0047220 xref: MetaCyc:2.4.1.134-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006533 name: sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol-3-phosphate + UDP-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + UDP." [EC:2.4.1.137, MetaCyc:2.4.1.137-RXN] synonym: "floridoside phosphate synthase activity" EXACT [EC:2.4.1.137] synonym: "floridoside phosphate synthetase activity" EXACT [EC:2.4.1.137] synonym: "floridoside-phosphate synthase activity" EXACT [EC:2.4.1.137] synonym: "FPS" RELATED [EC:2.4.1.137] synonym: "UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase activity" EXACT [EC:2.4.1.137] synonym: "UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.137] synonym: "UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase activity" EXACT [EC:2.4.1.137] synonym: "UDPgalactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.137] xref: EC:2.4.1.137 xref: GO:0047221 xref: MetaCyc:2.4.1.137-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006534 name: mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP." [EC:2.4.1.138, MetaCyc:2.4.1.138-RXN] synonym: "alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.138] synonym: "UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.138] synonym: "uridine diphosphoacetylglucosamine mannoside alpha1->2-alphacetylglucosaminyltransferase activity" EXACT [EC:2.4.1.138] xref: EC:2.4.1.138 xref: GO:0047222 xref: MetaCyc:2.4.1.138-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006535 name: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP." [EC:2.4.1.146, MetaCyc:2.4.1.146-RXN] synonym: "elongation 3-beta-GalNAc-transferase activity" RELATED [EC:2.4.1.146] synonym: "elongation 3beta-GalNAc-transferase activity" EXACT [EC:2.4.1.146] synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.146] synonym: "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to -D-galactose of beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.146] synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)" EXACT [EC:2.4.1.146] xref: EC:2.4.1.146 xref: GO:0047223 xref: MetaCyc:2.4.1.146-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006536 name: acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP." [EC:2.4.1.147, MetaCyc:2.4.1.147-RXN] synonym: "core 3-beta-GlcNAc-transferase activity" RELATED [EC:2.4.1.147] synonym: "core 3beta-GlcNAc-transferase activity" EXACT [EC:2.4.1.147] synonym: "mucin core 3 beta3-GlcNAc-transferase activity" EXACT [EC:2.4.1.147] synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity" EXACT [EC:2.4.1.147] synonym: "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.147] synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.147] xref: EC:2.4.1.147 xref: GO:0047224 xref: MetaCyc:2.4.1.147-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006537 name: acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP." [EC:2.4.1.148, MetaCyc:2.4.1.148-RXN] synonym: "core 4 beta6-GalNAc-transferase activity" EXACT [EC:2.4.1.148] synonym: "core 6-beta-GalNAc-transferase B activity" RELATED [EC:2.4.1.148] synonym: "core 6beta-GalNAc-transferase B" RELATED [EC:2.4.1.148] synonym: "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity" EXACT [EC:2.4.1.148] synonym: "UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.148] synonym: "uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B" RELATED [EC:2.4.1.148] xref: EC:2.4.1.148 xref: GO:0047225 xref: MetaCyc:2.4.1.148-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006538 name: indolylacetyl-myo-inositol galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: indole-3-acetyl-myo-inositol + UDP-galactose = 5-O-(indol-3-ylacetyl-myo-inositol)-D-galactoside + UDP." [EC:2.4.1.156, MetaCyc:2.4.1.156-RXN] synonym: "indol-3-ylacetyl-myo-inositol galactoside synthase activity" EXACT [EC:2.4.1.156] synonym: "UDP-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase activity" EXACT [EC:2.4.1.156] synonym: "UDP-galactose:indol-3-ylacetyl-myo-inositol 5-O-D-galactosyltransferase activity" EXACT [EC:2.4.1.156] synonym: "uridine diphosphogalactose-indolylacetylinositol galactosyltransferase activity" EXACT [EC:2.4.1.156] xref: EC:2.4.1.156 xref: GO:0047227 xref: MetaCyc:2.4.1.156-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006539 name: 1,2-diacylglycerol 3-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP." [EC:2.4.1.157, MetaCyc:2.4.1.157-RXN] subset: gosubset_prok synonym: "UDP-glucose-diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] synonym: "UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase activity" EXACT [EC:2.4.1.157] synonym: "UDP-glucose:1,2-diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] synonym: "UDPglucose:1,2-diacylglycerol 3-D-glucosyltransferase activity" EXACT [EC:2.4.1.157] synonym: "UDPglucose:diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] synonym: "uridine diphosphoglucose-diacylglycerol glucosyltransferase activity" EXACT [EC:2.4.1.157] xref: EC:2.4.1.157 xref: GO:0047228 xref: MetaCyc:2.4.1.157-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006540 name: 13-hydroxydocosanoate 13-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP." [EC:2.4.1.158, MetaCyc:2.4.1.158-RXN] synonym: "13-glucosyloxydocosanoate 2'-beta-glucosyltransferase activity" EXACT [EC:2.4.1.158] synonym: "UDP-glucose-13-hydroxydocosanoate glucosyltransferase activity" EXACT [EC:2.4.1.158] synonym: "UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.158] synonym: "UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase activity" EXACT [EC:2.4.1.158] synonym: "UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.158] synonym: "uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase activity" EXACT [EC:2.4.1.158] xref: EC:2.4.1.158 xref: GO:0047229 xref: MetaCyc:HYDROXYDOCOSANOATE-TRANS-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006541 name: flavonol-3-O-glucoside L-rhamnosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP." [EC:2.4.1.159, MetaCyc:2.4.1.159-RXN] synonym: "UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase activity" EXACT [EC:2.4.1.159] synonym: "UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase activity" EXACT [EC:2.4.1.159] synonym: "uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase activity" EXACT [EC:2.4.1.159] xref: EC:2.4.1.159 xref: GO:0047230 xref: MetaCyc:2.4.1.159-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006542 name: pyridoxine 5'-O-beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + UDP." [EC:2.4.1.160, MetaCyc:2.4.1.160-RXN] synonym: "UDP-glucose-pyridoxine glucosyltransferase activity" EXACT [EC:2.4.1.160] synonym: "UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.160] synonym: "UDP-glucose:pyridoxine 5'-O-beta-glucosyltransferase activity" EXACT [EC:2.4.1.160] synonym: "UDPglucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.160] synonym: "uridine diphosphoglucose-pyridoxine 5'-beta-glucosyltransferase activity" EXACT [EC:2.4.1.160] xref: EC:2.4.1.160 xref: GO:0047231 xref: MetaCyc:2.4.1.160-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006543 name: galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP." [EC:2.4.1.164, MetaCyc:2.4.1.164-RXN] synonym: "UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.164] synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase" BROAD [EC:2.4.1.164] xref: EC:2.4.1.164 xref: GO:0047232 xref: MetaCyc:2.4.1.164-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006544 name: N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP." [EC:2.4.1.165, MetaCyc:2.4.1.165-RXN] synonym: "UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.165] synonym: "uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.165] xref: EC:2.4.1.165 xref: GO:0047233 xref: MetaCyc:2.4.1.165-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0006545 name: raffinose-raffinose alpha-galactotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose." [EC:2.4.1.166, MetaCyc:2.4.1.166-RXN] subset: gosubset_prok synonym: "raffinose (raffinose donor) galactosyltransferase activity" EXACT [EC:2.4.1.166] synonym: "raffinose-raffinose a-galactosyltransferase activity" EXACT [] synonym: "raffinose-raffinose alpha-galactosyltransferase activity" EXACT [] synonym: "raffinose:raffinose alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.166] synonym: "raffinose:raffinose alpha-galactosyltransferase activity" EXACT [EC:2.4.1.166] xref: EC:2.4.1.166 xref: GO:0047234 xref: MetaCyc:2.4.1.166-RXN is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0006546 name: sucrose 6F-alpha-galactotransferase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP." [EC:2.4.1.167, MetaCyc:2.4.1.167-RXN] synonym: "sucrose 6(F)-alpha-galactosyltransferase activity" EXACT [] synonym: "sucrose 6F-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.167] synonym: "UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.167] synonym: "UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.167] synonym: "UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.167] synonym: "uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity" EXACT [EC:2.4.1.167] xref: EC:2.4.1.167 xref: GO:0047235 xref: MetaCyc:2.4.1.167-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006547 name: methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CH(3)-N(O)=N-CH(2)OH + UDP-D-glucose = cycasin + UDP." [EC:2.4.1.171, MetaCyc:2.4.1.171-RXN] synonym: "cycasin synthase activity" EXACT [EC:2.4.1.171] synonym: "methyl-ONN-azoxymethanol glucosyltransferase activity" EXACT [] synonym: "UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.171] synonym: "UDPglucose-methylazoxymethanol glucosyltransferase activity" EXACT [EC:2.4.1.171] synonym: "uridine diphosphoglucose-methylazoxymethanol glucosyltransferase activity" EXACT [EC:2.4.1.171] xref: EC:2.4.1.171 xref: GO:0047236 xref: MetaCyc:2.4.1.171-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006548 name: glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP." [EC:2.4.1.174, MetaCyc:2.4.1.174-RXN] synonym: "glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [] synonym: "N-acetylgalactosaminyltransferase I activity" EXACT [] synonym: "UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.174] synonym: "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I" RELATED [EC:2.4.1.174] synonym: "uridine diphosphoacetylgalactosamine-chondroitinacetylgalactosaminyltransferase I activity" EXACT [EC:2.4.1.174] xref: EC:2.4.1.174 xref: GO:0047237 xref: MetaCyc:2.4.1.174-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0006549 name: glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP." [EC:2.4.1.175, MetaCyc:2.4.1.175-RXN] synonym: "chondroitin synthase activity" EXACT [EC:2.4.1.175] synonym: "glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" EXACT [] synonym: "glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [] synonym: "N-acetylgalactosaminyltransferase II activity" EXACT [] synonym: "UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.175] synonym: "UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.175] synonym: "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity" EXACT [EC:2.4.1.175] xref: EC:2.4.1.175 xref: GO:0047238 xref: MetaCyc:2.4.1.175-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0006550 name: hydroxymandelonitrile glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = taxiphyllin + UDP." [EC:2.4.1.178, MetaCyc:2.4.1.178-RXN] synonym: "cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.178] synonym: "UDP-glucose:4-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.178] synonym: "UDPglucose:4-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.178] xref: EC:2.4.1.178 xref: GO:0047239 xref: MetaCyc:2.4.1.178-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006551 name: lactosylceramide beta-1,3-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactosyl-1,4-beta-D-glucosyl-R + UDP-galactose = D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R + UDP." [EC:2.4.1.179, MetaCyc:2.4.1.179-RXN] synonym: "UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.179] synonym: "UDPgalactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.179] synonym: "uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase activity" EXACT [EC:2.4.1.179] xref: EC:2.4.1.179 xref: GO:0047240 xref: MetaCyc:2.4.1.179-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity is_a: CCO:F0007345 ! beta-1,3-galactosyltransferase activity [Term] id: CCO:F0006552 name: lipopolysaccharide N-acetylmannosaminouronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP." [EC:2.4.1.180, MetaCyc:2.4.1.180-RXN] synonym: "LPS N-acetylmannosaminouronosyltransferase activity" EXACT [] synonym: "ManNAcA transferase activity" EXACT [EC:2.4.1.180] synonym: "UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase activity" EXACT [EC:2.4.1.180] synonym: "uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase activity" EXACT [EC:2.4.1.180] xref: EC:2.4.1.180 xref: GO:0047241 xref: MetaCyc:2.4.1.180-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006553 name: hydroxyanthraquinone glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP." [EC:2.4.1.181, MetaCyc:2.4.1.181-RXN] synonym: "anthraquinone-specific glucosyltransferase activity" EXACT [EC:2.4.1.181] synonym: "UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity" EXACT [EC:2.4.1.181] synonym: "UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity" EXACT [EC:2.4.1.181] synonym: "uridine diphosphoglucose-anthraquinone glucosyltransferase activity" EXACT [EC:2.4.1.181] xref: EC:2.4.1.181 xref: GO:0047242 xref: MetaCyc:2.4.1.181-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006554 name: flavanone 7-O-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP." [EC:2.4.1.185, MetaCyc:2.4.1.185-RXN] synonym: "hesperetin 7-O-glucosyl-transferase activity" EXACT [EC:2.4.1.185] synonym: "naringenin 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.185] synonym: "UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.185] synonym: "UDPglucose:flavanone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.185] synonym: "uridine diphosphoglucose-flavanone 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.185] xref: EC:2.4.1.185 xref: GO:0047243 xref: MetaCyc:2.4.1.185-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006555 name: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP." [EC:2.4.1.187, MetaCyc:2.4.1.187-RXN] subset: gosubset_prok synonym: "N-acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] synonym: "UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] synonym: "UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] synonym: "uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase activity" EXACT [EC:2.4.1.187] xref: EC:2.4.1.187 xref: GO:0047244 xref: MetaCyc:TEICHOICSYN2-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006556 name: N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP." [EC:2.4.1.188, MetaCyc:2.4.1.188-RXN] synonym: "UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase activity" EXACT [EC:2.4.1.188] synonym: "UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.188] synonym: "UDPglucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.188] synonym: "uridine diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol glucosyltransferase activity" EXACT [EC:2.4.1.188] xref: EC:2.4.1.188 xref: GO:0047245 xref: MetaCyc:2.4.1.188-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006557 name: luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: luteolin 7-O-glucuronide + UDP-D-glucuronate = luteolin 7-O-beta-D-diglucuronide + UDP." [EC:2.4.1.190, MetaCyc:2.4.1.190-RXN] synonym: "LMT activity" RELATED [EC:2.4.1.190] synonym: "luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.190] synonym: "UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase activity" EXACT [EC:2.4.1.190] synonym: "UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.190] synonym: "uridine diphosphoglucuronate-luteolin 7-O-glucuronide glucuronosyltransferase activity" EXACT [EC:2.4.1.190] xref: EC:2.4.1.190 xref: GO:0047246 xref: MetaCyc:2.4.1.190-RXN is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0006558 name: luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: luteolin 7-O-beta-D-glucuronide + UDP-D-glucuronate = luteolin 7-O-[beta-D-glucuronosyl-(1,2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + UDP." [EC:2.4.1.191, MetaCyc:2.4.1.191-RXN] synonym: "LDT" RELATED [EC:2.4.1.191] synonym: "UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase activity" EXACT [EC:2.4.1.191] synonym: "UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.191] synonym: "UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase activity" EXACT [EC:2.4.1.191] synonym: "UDPglucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.191] synonym: "uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase activity" EXACT [EC:2.4.1.191] xref: EC:2.4.1.191 xref: GO:0047247 xref: MetaCyc:2.4.1.191-RXN is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0006559 name: nuatigenin 3-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (20S,22S,25S)-22,25-epoxyfurost-5-ene-3-beta,26-diol + UDP-D-glucose = (20S,22S,25S)-22,25-epoxyfurost-5-ene-3-beta,26-diol 3-O-beta-D-glucoside + UDP." [EC:2.4.1.192, MetaCyc:2.4.1.192-RXN] synonym: "nuatigenin 3beta-glucosyltransferase activity" EXACT [EC:2.4.1.192] synonym: "UDP-glucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.192] synonym: "UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.192] synonym: "uridine diphosphoglucose-nuatigenin glucosyltransferase activity" EXACT [EC:2.4.1.192] xref: EC:2.4.1.192 xref: GO:0047248 xref: MetaCyc:2.4.1.192-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006560 name: sarsapogenin 3-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (25S)-5-beta-spirostan-3-beta-ol + UDP-D-glucose = (25S)-5-beta-spirostan-3-beta-ol 3-O-beta-D-glucoside + UDP." [EC:2.4.1.193, MetaCyc:2.4.1.193-RXN] synonym: "sarsapogenin 3beta-glucosyltransferase activity" EXACT [EC:2.4.1.193] synonym: "UDP-glucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.193] synonym: "UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.193] synonym: "uridine diphosphoglucose-sarsapogenin glucosyltransferase activity" EXACT [EC:2.4.1.193] xref: EC:2.4.1.193 xref: GO:0047249 xref: MetaCyc:2.4.1.193-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006561 name: 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: p-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + UDP." [EC:2.4.1.194, MetaCyc:2.4.1.194-RXN] synonym: "HBA glucosyltransferase activity" EXACT [EC:2.4.1.194] synonym: "p-hydroxybenzoate glucosyltransferase activity" EXACT [EC:2.4.1.194] synonym: "PHB glucosyltransferase activity" EXACT [EC:2.4.1.194] synonym: "PHB-O-glucosyltransferase activity" EXACT [EC:2.4.1.194] synonym: "UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase activity" EXACT [EC:2.4.1.194] synonym: "UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.194] synonym: "UDPglucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.194] synonym: "uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase activity" EXACT [EC:2.4.1.194] xref: EC:2.4.1.194 xref: GO:0047250 xref: MetaCyc:2.4.1.194-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006562 name: thiohydroximate beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP." [EC:2.4.1.195, MetaCyc:2.4.1.195-RXN] synonym: "desulfoglucosinolate-uridine diphosphate glucosyltransferase activity" EXACT [EC:2.4.1.195] synonym: "N-hydroxythioamide S-beta-glucosyltransferase activity" EXACT [EC:2.4.1.195] synonym: "thiohydroximate glucosyltransferase activity" EXACT [EC:2.4.1.195] synonym: "thiohydroximate S-glucosyltransferase activity" EXACT [EC:2.4.1.195] synonym: "UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.195] synonym: "UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.195] synonym: "UDPG:thiohydroximate glucosyltransferase activity" EXACT [EC:2.4.1.195] synonym: "uridine diphosphoglucose-thiohydroximate glucosyltransferase activity" EXACT [EC:2.4.1.195] xref: EC:2.4.1.195 xref: GO:0047251 xref: MetaCyc:2.4.1.195-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006563 name: beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,6-alpha-D-mannosyloligodaccharide + beta-D-mannosylphosphodecaprenol = 1,6-alpha-D-mannosyl-1,6-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate." [EC:2.4.1.199, MetaCyc:2.4.1.199-RXN] synonym: "beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.199] synonym: "mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase activity" EXACT [EC:2.4.1.199] xref: EC:2.4.1.199 xref: GO:0047252 xref: MetaCyc:2.4.1.199-RXN is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0006564 name: alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP." [EC:2.4.1.201, MetaCyc:2.4.1.201-RXN] synonym: "mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyl-transferase activity" EXACT [] synonym: "mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.201] synonym: "N-acetylglucosaminyltransferase VI activity" RELATED [EC:2.4.1.201] synonym: "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI activity" EXACT [EC:2.4.1.201] synonym: "UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.201] synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI" RELATED [EC:2.4.1.201] synonym: "uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI activity" EXACT [EC:2.4.1.201] xref: EC:2.4.1.201 xref: GO:0047253 xref: MetaCyc:2.4.1.201-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006565 name: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP." [EC:2.4.1.202, MetaCyc:2.4.1.202-RXN] synonym: "UDP-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity" EXACT [EC:2.4.1.202] synonym: "UDPglucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity" EXACT [EC:2.4.1.202] synonym: "uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase activity" EXACT [EC:2.4.1.202] xref: EC:2.4.1.202 xref: GO:0047254 xref: MetaCyc:2.4.1.202-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006566 name: galactogen 6-beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP." [EC:2.4.1.205, MetaCyc:2.4.1.205-RXN] synonym: "1,6-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] synonym: "beta-(1-6)-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] synonym: "galactogen 6beta-galactosyltransferase activity" EXACT [EC:2.4.1.205] synonym: "UDP-galactose:galactogen beta-1,6-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] synonym: "UDPgalactose:galactogen beta-1,6-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] synonym: "uridine diphosphogalactose-galactogen galactosyltransferase activity" EXACT [EC:2.4.1.205] xref: EC:2.4.1.205 xref: GO:0047255 xref: MetaCyc:2.4.1.205-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006567 name: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP." [EC:2.4.1.206, MetaCyc:2.4.1.206-RXN] synonym: "beta1->3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] synonym: "LA2 synthase activity" EXACT [EC:2.4.1.206] synonym: "lactosylceramide beta-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] synonym: "UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] synonym: "uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.206] xref: EC:2.4.1.206 xref: GO:0047256 xref: MetaCyc:2.4.1.206-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006568 name: diglucosyl diacylglycerol synthase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)sn-glycerol." [EC:2.4.1.208, MetaCyc:2.4.1.208-RXN] synonym: "DGlcDAG synthase activity" EXACT [EC:2.4.1.208] synonym: "diglucosyl diacylglycerol (DGlcDAG) synthase activity" EXACT [] synonym: "MGlcDAG (1->2) glucosyltransferase activity" EXACT [EC:2.4.1.208] synonym: "monoglucosyl diacylglycerol (1->2) glucosyltransferase activity" EXACT [EC:2.4.1.208] synonym: "UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase activity" EXACT [EC:2.4.1.208] xref: EC:2.4.1.208 xref: GO:0047257 xref: MetaCyc:2.4.1.208-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006569 name: sphingosine beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sphingosine + UDP-galactose = psychosine + UDP." [EC:2.4.1.23, MetaCyc:2.4.1.23-RXN] synonym: "galactosyl-sphingosine transferase activity" EXACT [EC:2.4.1.23] synonym: "psychosine-UDP galactosyltransferase activity" EXACT [EC:2.4.1.23] synonym: "psychosine-uridine diphosphate galactosyltransferase activity" EXACT [EC:2.4.1.23] synonym: "UDP-galactose:sphingosine 1-beta-galactotransferase activity" EXACT [EC:2.4.1.23] synonym: "UDPgalactose:sphingosine 1-beta-galactotransferase activity" EXACT [EC:2.4.1.23] synonym: "UDPgalactose:sphingosine O-galactosyl transferase activity" EXACT [EC:2.4.1.23] synonym: "uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity" EXACT [EC:2.4.1.23] xref: EC:2.4.1.23 xref: GO:0047258 xref: MetaCyc:2.4.1.23-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006570 name: glucomannan 4-beta-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP." [EC:2.4.1.32, MetaCyc:2.4.1.32-RXN] synonym: "GDP-man-beta-mannan manosyltransferase activity" EXACT [EC:2.4.1.32] synonym: "GDP-mannose:glucomannan 1,4-beta-D-mannosyltransferase activity" EXACT [] synonym: "glucomannan 4-b-mannosyltransferase activity" EXACT [] synonym: "glucomannan-synthase activity" EXACT [] xref: EC:2.4.1.32 xref: GO:0047259 xref: MetaCyc:2.4.1.32-RXN is_a: CCO:F0004117 ! beta-1,4-mannosyltransferase activity [Term] id: CCO:F0006571 name: alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP." [EC:2.4.1.36, MetaCyc:2.4.1.36-RXN] synonym: "GDP-glucose-glucosephosphate glucosyltransferase activity" EXACT [EC:2.4.1.36] synonym: "GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.36] synonym: "GDPglucose-glucose-phosphate glucosyltransferase activity" EXACT [EC:2.4.1.36] synonym: "GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.36] synonym: "guanosine diphosphoglucose-glucose phosphate glucosyltransferase activity" EXACT [EC:2.4.1.36] synonym: "trehalose phosphate synthase (GDP-forming) activity" EXACT [EC:2.4.1.36] xref: EC:2.4.1.36 xref: GO:0047260 xref: MetaCyc:2.4.1.36-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006572 name: steroid N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: estradiol-17-alpha 3-D-glucuronoside + UDP-N-acetyl-D-glucosamine = 17-alpha-(N-acetyl-D-glucosaminyl)estradiol 3-D-glucuronoside + UDP." [EC:2.4.1.39, MetaCyc:2.4.1.39-RXN] synonym: "hydroxy steroid acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] synonym: "steroid acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] synonym: "UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] synonym: "uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.39] xref: EC:2.4.1.39 xref: GO:0047261 xref: MetaCyc:2.4.1.39-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006573 name: polygalacturonate 4-alpha-galacturonosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP." [EC:2.4.1.43, MetaCyc:2.4.1.43-RXN] synonym: "UDP galacturonate-polygalacturonate alpha-galacturonosyltransferase activity" EXACT [EC:2.4.1.43] synonym: "UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase activity" EXACT [EC:2.4.1.43] synonym: "uridine diphosphogalacturonate-polygalacturonate alpha-galacturonosyltransferase activity" EXACT [EC:2.4.1.43] xref: EC:2.4.1.43 xref: GO:0047262 xref: GO:0050375 xref: MetaCyc:2.4.1.43-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006574 name: N-acylsphingosine galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP." [EC:2.4.1.47, MetaCyc:2.4.1.47-RXN] synonym: "UDP galactose-N-acylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.47] synonym: "UDP-galactose:N-acylsphingosine D-galactosyltransferase activity" EXACT [EC:2.4.1.47] synonym: "UDPgalactose:N-acylsphingosine D-galactosyltransferase activity" EXACT [EC:2.4.1.47] synonym: "uridine diphosphogalactose-acylsphingosine galactosyltransferase activity" EXACT [EC:2.4.1.47] xref: EC:2.4.1.47 xref: GO:0047263 xref: MetaCyc:2.4.1.47-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006575 name: heteroglycan alpha-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: heteroglycan + GDP-mannose = 1,2(or 1,3)-alpha-D-mannosylheteroglycan + GDP." [EC:2.4.1.48, MetaCyc:2.4.1.48-RXN] synonym: "GDP mannose alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] synonym: "GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.48] synonym: "guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity" EXACT [EC:2.4.1.48] xref: EC:2.4.1.48 xref: GO:0047264 xref: MetaCyc:2.4.1.48-RXN is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0006576 name: poly(glycerol-phosphate) alpha-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP." [EC:2.4.1.52, MetaCyc:2.4.1.52-RXN] subset: gosubset_prok synonym: "UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity" EXACT [EC:2.4.1.52] synonym: "UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.52] synonym: "UDPglucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.52] synonym: "uridine diphosphoglucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity" EXACT [EC:2.4.1.52] xref: EC:2.4.1.52 xref: GO:0047265 xref: MetaCyc:2.4.1.52-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006577 name: poly(ribitol-phosphate) beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP." [EC:2.4.1.53, MetaCyc:2.4.1.53-RXN] synonym: "UDP glucose-poly(ribitol-phosphate) beta-glucosyltransferase activity" EXACT [EC:2.4.1.53] synonym: "UDP-D-glucose polyribitol phosphate glucosyl transferase activity" EXACT [EC:2.4.1.53] synonym: "UDP-D-glucose:polyribitol phosphate glucosyl transferase activity" EXACT [EC:2.4.1.53] synonym: "UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.53] synonym: "UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.53] synonym: "uridine diphosphoglucose-poly(ribitol-phosphate) beta-glucosyltransferase activity" EXACT [EC:2.4.1.53] xref: EC:2.4.1.53 xref: GO:0047266 xref: MetaCyc:2.4.1.53-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006578 name: undecaprenyl-phosphate mannosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: undecaprenyl phosphate + GDP-mannose = D-mannosyl-1-phosphoundecaprenol + GDP." [EC:2.4.1.54, MetaCyc:2.4.1.54-RXN] synonym: "GDP mannose-undecaprenyl phosphate mannosyltransferase activity" EXACT [EC:2.4.1.54] synonym: "GDP-D-mannose:lipid phosphate transmannosylase activity" EXACT [EC:2.4.1.54] synonym: "GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity" EXACT [EC:2.4.1.54] synonym: "guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity" EXACT [EC:2.4.1.54] xref: EC:2.4.1.54 xref: GO:0047267 xref: MetaCyc:2.4.1.54-RXN is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0006579 name: galactinol-raffinose galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol." [EC:2.4.1.67, MetaCyc:2.4.1.67-RXN] synonym: "alpha-D-(1->3)-galactosyl-myo-inositol:raffinose galactosyltransferase activity" EXACT [EC:2.4.1.67] synonym: "stachyose synthetase activity" EXACT [EC:2.4.1.67] xref: EC:2.4.1.67 xref: GO:0047268 xref: MetaCyc:2.4.1.67-RXN is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0006580 name: poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP." [EC:2.4.1.70, MetaCyc:2.4.1.70-RXN] synonym: "UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.70] synonym: "UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.70] synonym: "uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.70] xref: EC:2.4.1.70 xref: GO:0047269 xref: MetaCyc:2.4.1.70-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0006581 name: lipopolysaccharide glucosyltransferase II activity namespace: molecular_function def: "Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP." [EC:2.4.1.73, MetaCyc:2.4.1.73-RXN] synonym: "LPS glucosyltransferase II activity" EXACT [] synonym: "UDP-glucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.73] synonym: "UDPglucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.73] synonym: "uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase activity" EXACT [EC:2.4.1.73] xref: EC:2.4.1.73 xref: GO:0047270 xref: MetaCyc:2.4.1.73-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006582 name: glycosaminoglycan galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP." [EC:2.4.1.74, MetaCyc:2.4.1.74-RXN] synonym: "UDP-galactose:glycosaminoglycan D-galactosyltransferase activity" EXACT [EC:2.4.1.74] synonym: "UDPgalactose:glycosaminoglycan D-galactosyltransferase activity" EXACT [EC:2.4.1.74] synonym: "uridine diphosphogalactose-mucopolysaccharide galactosyltransferase activity" EXACT [EC:2.4.1.74] xref: EC:2.4.1.74 xref: GO:0047271 xref: MetaCyc:2.4.1.74-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006583 name: phosphopolyprenol glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP." [EC:2.4.1.78, MetaCyc:2.4.1.78-RXN] synonym: "UDP-glucose:phosphopolyprenol D-glucosyltransferase activity" EXACT [EC:2.4.1.78] synonym: "UDPglucose:phosphopolyprenol D-glucosyltransferase activity" EXACT [EC:2.4.1.78] synonym: "UDPglucose:polyprenol monophosphate glucosyltransferase activity" EXACT [EC:2.4.1.78] synonym: "uridine diphosphoglucose-polyprenol monophosphate glucosyltransferase activity" EXACT [EC:2.4.1.78] xref: EC:2.4.1.78 xref: GO:0047272 xref: MetaCyc:2.4.1.78-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006584 name: galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide." [EC:2.4.1.79, MetaCyc:2.4.1.79-RXN] synonym: "beta-3GalNAc-T1 activity" EXACT [EC:2.4.1.79] synonym: "beta3GalNAc-T1" RELATED [EC:2.4.1.79] synonym: "galactosylgalactosylglucosylceramide beta-D- activity" EXACT [EC:2.4.1.79] synonym: "globoside synthase activity" EXACT [EC:2.4.1.79] synonym: "globoside synthetase activity" EXACT [EC:2.4.1.79] synonym: "globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] synonym: "globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase activity" EXACT [] synonym: "UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide 3III-beta-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.79] synonym: "UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.79] synonym: "UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] synonym: "UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] synonym: "uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.79] xref: EC:2.4.1.79 xref: GO:0047226 xref: GO:0047273 xref: MetaCyc:2.4.1.79-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0006585 name: galactinol-sucrose galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol." [EC:2.4.1.82, MetaCyc:2.4.1.82-RXN] synonym: "1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.82] synonym: "alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.82] synonym: "galactinol:sucrose 6-galactosyl transferase activity" EXACT [] synonym: "galactosyltransferase, galactinol-sucrose" EXACT [] synonym: "raffinose synthase activity" EXACT [] xref: EC:2.4.1.82 xref: GO:0047274 xref: MetaCyc:2.4.1.82-RXN is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0006586 name: glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP." [EC:2.4.1.86, MetaCyc:2.4.1.86-RXN] synonym: "GalT-4" RELATED [EC:2.4.1.86] synonym: "paragloboside synthase activity" EXACT [EC:2.4.1.86] synonym: "UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.86] synonym: "UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity" EXACT [EC:2.4.1.86] synonym: "uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide galactosyltransferase activity" EXACT [EC:2.4.1.86] xref: EC:2.4.1.86 xref: GO:0047275 xref: MetaCyc:2.4.1.86-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006587 name: N-acetyllactosaminide 3-alpha-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP." [EC:2.4.1.87, MetaCyc:2.4.1.87-RXN] synonym: "alpha-galactosyltransferase activity" RELATED [EC:2.4.1.87] synonym: "beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "beta-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity" EXACT [] synonym: "glucosaminylglycopeptide alpha-1,3-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "N-acetyllactosaminide alpha-1,3-galactosyltransferase activity" EXACT [] synonym: "UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha-(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-Gal:Galbeta1->4GlcNAc-R alpha1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-Gal:N-acetyllactosaminide alpha(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-Gal:N-acetyllactosaminide alpha-(1,3)-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "uridine diphosphogalactose-acetyllactosamine alpha-1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "uridine diphosphogalactose-acetyllactosamine alpha1->3-galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "uridine diphosphogalactose-acetyllactosamine galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-glucosylceramide galactosyltransferase activity" EXACT [EC:2.4.1.87] synonym: "uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase activity" EXACT [EC:2.4.1.87] xref: EC:2.4.1.87 xref: GO:0003946 xref: GO:0047276 xref: MetaCyc:2.4.1.151-RXN xref: MetaCyc:2.4.1.87-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006588 name: globoside alpha-N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP." [EC:2.4.1.88, MetaCyc:2.4.1.88-RXN] synonym: "Forssman synthase activity" RELATED [EC:2.4.1.88] synonym: "forssman synthase activity" EXACT [EC:2.4.1.88] synonym: "globoside acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.88] synonym: "UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.88] synonym: "uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.88] xref: EC:2.4.1.88 xref: GO:0047277 xref: MetaCyc:2.4.1.88-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0006589 name: bilirubin-glucuronoside glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin-bisglucuronoside + bilirubin." [EC:2.4.1.95, MetaCyc:2.4.1.95-RXN] synonym: "bilirubin glucuronoside glucuronosyltransferase activity" EXACT [EC:2.4.1.95] synonym: "bilirubin monoglucuronide transglucuronidase activity" EXACT [EC:2.4.1.95] synonym: "bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase activity" EXACT [EC:2.4.1.95] xref: EC:2.4.1.95 xref: GO:0047278 xref: MetaCyc:2.4.1.95-RXN is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0006590 name: sn-glycerol-3-phosphate 1-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol-3-phosphate + UDP-galactose = alpha-D-galactosyl-(1,1')-sn-glycerol 3-phosphate + UDP." [EC:2.4.1.96, MetaCyc:2.4.1.96-RXN] synonym: "glycerol 3-phosphate 1alpha-galactosyltransferase activity" EXACT [EC:2.4.1.96] synonym: "isofloridoside-phosphate synthase activity" EXACT [EC:2.4.1.96] synonym: "UDP-Gal:sn-glycero-3-phosphoric acid 1-alpha-galactosyl-transferase activity" EXACT [EC:2.4.1.96] synonym: "UDP-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.96] synonym: "UDPgalactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.96] synonym: "UDPgalactose:sn-glycerol-3-phosphate alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.96] synonym: "uridine diphosphogalactose-glycerol phosphate galactosyltransferase activity" EXACT [EC:2.4.1.96] xref: EC:2.4.1.96 xref: GO:0047279 xref: MetaCyc:2.4.1.96-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0006591 name: nicotinamide phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: pyrophosphate + nicotinamide nucleotide = PRPP + niacinamide." [EC:2.4.2.12, MetaCyc:2.4.2.12-RXN] synonym: "nicotinamide mononucleotide pyrophosphorylase activity" EXACT [EC:2.4.2.12] synonym: "nicotinamide mononucleotide synthetase activity" EXACT [EC:2.4.2.12] synonym: "nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.12] synonym: "NMN diphosphorylase activity" EXACT [EC:2.4.2.12] synonym: "NMN pyrophosphorylase activity" EXACT [EC:2.4.2.12] synonym: "NMN synthetase activity" EXACT [EC:2.4.2.12] xref: EC:2.4.2.12 xref: GO:0047280 xref: MetaCyc:2.4.2.12-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0006592 name: dioxotetrahydropyrimidine phosphoribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine." [EC:2.4.2.20, MetaCyc:2.4.2.20-RXN] synonym: "2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.20] synonym: "dioxotetrahydropyrimidine phosphoribosyl transferase activity" EXACT [EC:2.4.2.20] synonym: "dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase activity" EXACT [EC:2.4.2.20] synonym: "dioxotetrahydropyrimidine-ribonucleotide diphosphorylase activity" EXACT [EC:2.4.2.20] synonym: "dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase activity" EXACT [EC:2.4.2.20] xref: EC:2.4.2.20 xref: GO:0047281 xref: MetaCyc:2.4.2.20-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0006593 name: dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: streptidine 6-phosphate + dTDP-L-dihydrostreptose = O-1,4-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP." [EC:2.4.2.27, MetaCyc:2.4.2.27-RXN] subset: gosubset_prok synonym: "dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase activity" EXACT [EC:2.4.2.27] synonym: "dTDPdihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity" EXACT [EC:2.4.2.27] synonym: "thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase activity" EXACT [EC:2.4.2.27] xref: EC:2.4.2.27 xref: GO:0047282 xref: MetaCyc:2.4.2.27-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0006594 name: dolichyl-phosphate D-xylosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP." [EC:2.4.2.32, MetaCyc:2.4.2.32-RXN] synonym: "UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase activity" EXACT [EC:2.4.2.32] xref: EC:2.4.2.32 xref: GO:0047283 xref: MetaCyc:2.4.2.32-RXN is_a: CCO:F0005581 ! UDP-xylosyltransferase activity [Term] id: CCO:F0006595 name: dolichyl-xylosyl-phosphate-protein xylosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein." [EC:2.4.2.33, MetaCyc:2.4.2.33-RXN] synonym: "dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase activity" EXACT [EC:2.4.2.33] xref: EC:2.4.2.33 xref: GO:0047284 xref: MetaCyc:2.4.2.33-RXN is_a: CCO:F0005645 ! xylosyltransferase activity [Term] id: CCO:F0006596 name: flavonol-3-O-glycoside xylosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP." [EC:2.4.2.35, MetaCyc:2.4.2.35-RXN] synonym: "UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.35] xref: EC:2.4.2.35 xref: GO:0047285 xref: MetaCyc:2.4.2.35-RXN is_a: CCO:F0005581 ! UDP-xylosyltransferase activity [Term] id: CCO:F0006597 name: NAD+-diphthamide ADP-ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide." [EC:2.4.2.36, MetaCyc:2.4.2.36-RXN] subset: gosubset_prok synonym: "ADP-ribosyltransferase activity" BROAD [EC:2.4.2.36] synonym: "mono(ADP-ribosyl)transferase activity" BROAD [EC:2.4.2.36] synonym: "NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity" EXACT [EC:2.4.2.36] synonym: "NAD-diphthamide ADP-ribosyltransferase activity" EXACT [] xref: EC:2.4.2.36 xref: GO:0047286 xref: MetaCyc:2.4.2.36-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0006598 name: lactosylceramide alpha-2,6-N-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP." [EC:2.4.99.11, MetaCyc:2.4.99.11-RXN] synonym: "CMP-acetylneuraminate-lactosylceramide-sialyltransferase" BROAD [EC:2.4.99.11] synonym: "CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.11] synonym: "CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activity" EXACT [EC:2.4.99.11] synonym: "CMP-sialic acid:lactosylceramide sialyltransferase activity" EXACT [EC:2.4.99.11] synonym: "cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase" BROAD [EC:2.4.99.11] xref: EC:2.4.99.11 xref: GO:0047287 xref: MetaCyc:2.4.99.11-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0006599 name: monosialoganglioside sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP." [EC:2.4.99.2, MetaCyc:2.4.99.2-RXN] synonym: "CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.2] xref: EC:2.4.99.2 xref: GO:0047288 xref: MetaCyc:2.4.99.2-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0006600 name: galactosyldiacylglycerol alpha-2,3-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetylneuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP." [EC:2.4.99.5, MetaCyc:2.4.99.5-RXN] synonym: "CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.5] xref: EC:2.4.99.5 xref: GO:0047289 xref: MetaCyc:2.4.99.5-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0006602 name: lactosylceramide alpha-2,3-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3." [EC:2.4.99.9, MetaCyc:2.4.99.9-RXN] synonym: "CMP-acetylneuraminate-lactosylceramide-sialyltransferase" BROAD [EC:2.4.99.9] synonym: "CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity" EXACT [EC:2.4.99.9] synonym: "CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity" EXACT [EC:2.4.99.9] synonym: "CMP-sialic acid:lactosylceramide-sialyltransferase activity" EXACT [EC:2.4.99.9] synonym: "cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity" EXACT [EC:2.4.99.9] synonym: "cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase" BROAD [EC:2.4.99.9] synonym: "ganglioside GM3 synthase activity" EXACT [EC:2.4.99.9] synonym: "ganglioside GM3 synthetase activity" EXACT [EC:2.4.99.9] synonym: "GM3 synthase activity" EXACT [EC:2.4.99.9] synonym: "GM3 synthetase activity" EXACT [EC:2.4.99.9] synonym: "SAT 1" RELATED [EC:2.4.99.9] xref: EC:2.4.99.9 xref: GO:0047291 xref: MetaCyc:2.4.99.9-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0006603 name: trihydroxypterocarpan dimethylallyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + pyrophosphate." [EC:2.5.1.36, MetaCyc:2.5.1.36-RXN] synonym: "dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity" EXACT [EC:2.5.1.36] synonym: "dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase activity" EXACT [EC:2.5.1.36] synonym: "dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity" EXACT [EC:2.5.1.36] synonym: "dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity" EXACT [EC:2.5.1.36] xref: EC:2.5.1.36 xref: GO:0047292 xref: MetaCyc:2.5.1.36-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006604 name: 4-hydroxybenzoate nonaprenyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + pyrophosphate." [EC:2.5.1.39, MetaCyc:2.5.1.39-RXN] synonym: "4-hydroxybenzoate transferase activity" EXACT [EC:2.5.1.39] synonym: "nonaprenyl-4-hydroxybenzoate transferase activity" EXACT [EC:2.5.1.39] synonym: "p-hydroxybenzoate dimethylallyltransferase activity" EXACT [EC:2.5.1.39] synonym: "p-hydroxybenzoate polyprenyltransferase activity" EXACT [EC:2.5.1.39] synonym: "p-hydroxybenzoic acid-polyprenyl transferase activity" EXACT [EC:2.5.1.39] synonym: "p-hydroxybenzoic-polyprenyl transferase activity" EXACT [EC:2.5.1.39] synonym: "solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase activity" EXACT [EC:2.5.1.39] xref: EC:2.5.1.39 xref: GO:0047293 xref: MetaCyc:2.5.1.39-RXN is_a: CCO:F0000268 ! polyprenyltransferase activity [Term] id: CCO:F0006605 name: phosphoglycerol geranylgeranyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sn-glyceryl phosphate + geranylgeranyl-PP = sn-3-O-(geranylgeranyl)glyceryl 1-phosphate + diphosphate." [EC:2.5.1.41, MetaCyc:2.5.1.41-RXN] synonym: "geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.41] synonym: "geranylgeranyl-transferase activity" EXACT [EC:2.5.1.41] synonym: "glycerol phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.41] xref: EC:2.5.1.41 xref: GO:0047294 xref: MetaCyc:2.5.1.41-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006606 name: geranylgeranylglycerol-phosphate geranylgeranyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + geranylgeranyl-PP = 2,3-bis-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate." [EC:2.5.1.42, MetaCyc:2.5.1.42-RXN] synonym: "geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.42] synonym: "geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.42] synonym: "geranylgeranyltransferase II" RELATED [EC:2.5.1.42] xref: EC:2.5.1.42 xref: GO:0047295 xref: MetaCyc:2.5.1.42-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006607 name: homospermidine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine." [EC:2.5.1.44, MetaCyc:2.5.1.44-RXN] subset: gosubset_prok synonym: "putrescine:putrescine 4-aminobutyltransferase (ammonia-forming)" EXACT [EC:2.5.1.44] xref: EC:2.5.1.44 xref: GO:0047296 xref: MetaCyc:2.5.1.44-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006608 name: asparagine-oxo-acid transaminase activity namespace: molecular_function def: "Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate." [EC:2.6.1.14, MetaCyc:2.6.1.14-RXN] synonym: "asparagine--oxo-acid aminotransferase activity" EXACT [EC:2.6.1.14] synonym: "asparagine-keto acid aminotransferase activity" EXACT [EC:2.6.1.14] synonym: "asparagine-oxo-acid aminotransferase activity" EXACT [] synonym: "L-asparagine:2-oxo-acid aminotransferase activity" EXACT [EC:2.6.1.14] xref: EC:2.6.1.14 xref: GO:0047297 xref: MetaCyc:2.6.1.14-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006610 name: tryptophan-phenylpyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: phenylpyruvate + L-tryptophan = L-phenylalanine + indolepyruvate." [EC:2.6.1.28, MetaCyc:2.6.1.28-RXN] synonym: "L-tryptophan-alpha-ketoisocaproate aminotransferase activity" EXACT [EC:2.6.1.28] synonym: "L-tryptophan:phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.28] synonym: "tryptophan--phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.28] synonym: "tryptophan-phenylpyruvate aminotransferase activity" EXACT [] xref: EC:2.6.1.28 xref: GO:0047299 xref: MetaCyc:2.6.1.28-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006611 name: pyridoxamine-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + pyridoxamine = L-alanine + pyridoxal." [EC:2.6.1.30, MetaCyc:2.6.1.30-RXN] synonym: "pyridoxamine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.30] synonym: "pyridoxamine-pyruvate aminotransferase activity" EXACT [] synonym: "pyridoxamine-pyruvic transaminase" BROAD [EC:2.6.1.30] synonym: "pyridoxamine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.30] synonym: "pyridoxamineu-pyruvic transaminase activity" EXACT [EC:2.6.1.30] xref: EC:2.6.1.30 xref: GO:0047300 xref: MetaCyc:2.6.1.30-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006612 name: valine-3-methyl-2-oxovalerate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-keto-3-methyl-valerate + L-valine = L-iso-leucine + 2-keto-isovalerate." [EC:2.6.1.32, MetaCyc:2.6.1.32-RXN] synonym: "L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase activity" EXACT [EC:2.6.1.32] synonym: "valine--3-methyl-2-oxovalerate aminotransferase activity" EXACT [EC:2.6.1.32] synonym: "valine--isoleucine aminotransferase activity" EXACT [EC:2.6.1.32] synonym: "valine--isoleucine transaminase activity" EXACT [EC:2.6.1.32] synonym: "valine-2-keto-methylvalerate aminotransferase activity" EXACT [EC:2.6.1.32] synonym: "valine-3-methyl-2-oxovalerate aminotransferase activity" EXACT [] xref: EC:2.6.1.32 xref: GO:0047301 xref: MetaCyc:2.6.1.32-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006613 name: UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose." [EC:2.6.1.34, MetaCyc:2.6.1.34-RXN] synonym: "UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.34] synonym: "UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity" EXACT [] synonym: "UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase activity" EXACT [] synonym: "uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity" EXACT [EC:2.6.1.34] xref: EC:2.6.1.34 xref: GO:0047302 xref: MetaCyc:2.6.1.34-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006614 name: glycine-oxaloacetate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: oxaloacetic acid + L-glycine = L-aspartate + glyoxylate." [EC:2.6.1.35, MetaCyc:2.6.1.35-RXN] synonym: "glycine--oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.35] synonym: "glycine-oxalacetate aminotransferase activity" EXACT [EC:2.6.1.35] synonym: "glycine-oxaloacetate aminotransferase activity" EXACT [] synonym: "glycine:oxaloacetate aminotransferase activity" EXACT [EC:2.6.1.35] xref: EC:2.6.1.35 xref: GO:0047303 xref: MetaCyc:2.6.1.35-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006615 name: 2-aminoethylphosphonate-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + (2-aminoethyl)phosphonate = L-alanine + phosphonoacetaldehyde." [EC:2.6.1.37, MetaCyc:2.6.1.37-RXN] subset: gosubset_prok synonym: "(2-aminoethyl)phosphonate aminotransferase activity" EXACT [EC:2.6.1.37] synonym: "(2-aminoethyl)phosphonate transaminase activity" EXACT [EC:2.6.1.37] synonym: "(2-aminoethyl)phosphonate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.37] synonym: "(2-aminoethyl)phosphonate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.37] synonym: "(2-aminoethyl)phosphonic acid aminotransferase activity" EXACT [EC:2.6.1.37] synonym: "2-aminoethylphosphonate aminotransferase activity" EXACT [EC:2.6.1.37] synonym: "2-aminoethylphosphonate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.37] synonym: "2-aminoethylphosphonate-pyruvate aminotransferase activity" EXACT [] xref: EC:2.6.1.37 xref: GO:0047304 xref: MetaCyc:2.6.1.37-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006617 name: D-methionine-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + D-methionine = L-alanine + 2-keto-4-methylthiobutyrate." [EC:2.6.1.41, MetaCyc:2.6.1.41-RXN] synonym: "D-methionine aminotransferase activity" EXACT [EC:2.6.1.41] synonym: "D-methionine transaminase activity" EXACT [EC:2.6.1.41] synonym: "D-methionine--pyruvate aminotransferase activity" EXACT [EC:2.6.1.41] synonym: "D-methionine-pyruvate aminotransferase activity" EXACT [] synonym: "D-methionine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.41] xref: EC:2.6.1.41 xref: GO:0047306 xref: MetaCyc:2.6.1.41-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006618 name: diaminobutyrate-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + L-2,4-diaminobutanoate = L-aspartate-semialdehyde + L-alanine." [EC:2.6.1.46, MetaCyc:2.6.1.46-RXN] subset: gosubset_prok synonym: "diaminobutyrate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.46] synonym: "diaminobutyrate-pyruvate aminotransferase activity" EXACT [] synonym: "L-2,4-diaminobutanoate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.46] synonym: "L-diaminobutyric acid transaminase activity" EXACT [EC:2.6.1.46] xref: EC:2.6.1.46 xref: GO:0047307 xref: MetaCyc:2.6.1.46-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006619 name: alanine-oxomalonate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: oxomalonate + L-alanine = aminomalonate + pyruvate." [EC:2.6.1.47, MetaCyc:2.6.1.47-RXN] synonym: "alanine--oxomalonate aminotransferase activity" EXACT [EC:2.6.1.47] synonym: "alanine-ketomalonate (mesoxalate) transaminase activity" EXACT [EC:2.6.1.47] synonym: "alanine-oxomalonate aminotransferase activity" EXACT [] synonym: "L-alanine-ketomalonate transaminase activity" EXACT [EC:2.6.1.47] synonym: "L-alanine:oxomalonate aminotransferase activity" EXACT [EC:2.6.1.47] xref: EC:2.6.1.47 xref: GO:0047308 xref: MetaCyc:2.6.1.47-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006620 name: dihydroxyphenylalanine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + L-dihydroxy-phenylalanine = L-glutamate + 3,4-dihydroxyphenylpyruvate." [EC:2.6.1.49, MetaCyc:2.6.1.49-RXN] synonym: "3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.49] synonym: "aspartate-DOPP transaminase (ADT)" EXACT [EC:2.6.1.49] synonym: "dihydroxyphenylalanine aminotransferase activity" EXACT [] synonym: "dopa aminotransferase activity" EXACT [EC:2.6.1.49] synonym: "DOPA aminotransferase activity" EXACT [EC:2.6.1.49] synonym: "dopa transaminase activity" EXACT [EC:2.6.1.49] synonym: "glutamate-DOPP transaminase (GDT)" EXACT [EC:2.6.1.49] synonym: "L-dopa transaminase activity" EXACT [EC:2.6.1.49] synonym: "phenylalanine-DOPP transaminase (PDT)" EXACT [EC:2.6.1.49] xref: EC:2.6.1.49 xref: GO:0047309 xref: MetaCyc:2.6.1.49-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006621 name: glutamine-scyllo-inositol transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-keto-myo-inositol + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-keto-glutaramate." [EC:2.6.1.50, MetaCyc:2.6.1.50-RXN] subset: gosubset_prok synonym: "glutamine scyllo-inosose aminotransferase activity" EXACT [EC:2.6.1.50] synonym: "glutamine--scyllo-inosose aminotransferase activity" EXACT [EC:2.6.1.50] synonym: "glutamine--scyllo-inosose transaminase activity" EXACT [EC:2.6.1.50] synonym: "glutamine-scyllo-inosose aminotransferase activity" EXACT [] synonym: "glutamine-scyllo-inosose transaminase activity" EXACT [] synonym: "L-glutamine-keto-scyllo-inositol aminotransferase activity" EXACT [EC:2.6.1.50] synonym: "L-glutamine-scyllo-inosose transaminase activity" EXACT [EC:2.6.1.50] synonym: "L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase activity" EXACT [EC:2.6.1.50] xref: EC:2.6.1.50 xref: GO:0047310 xref: MetaCyc:2.6.1.50-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006622 name: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol = L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol." [EC:2.6.1.56, MetaCyc:2.6.1.56-RXN] synonym: "1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase activity" EXACT [] synonym: "1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase activity" EXACT [EC:2.6.1.56] synonym: "guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase activity" EXACT [EC:2.6.1.56] synonym: "L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase activity" EXACT [EC:2.6.1.56] xref: EC:2.6.1.56 xref: GO:0047311 xref: MetaCyc:2.6.1.56-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006623 name: phenylalanine(histidine) transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine." [EC:2.6.1.58, MetaCyc:2.6.1.58-RXN] synonym: "histidine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.58] synonym: "L-phenylalanine(L-histidine):pyruvate aminotransferase activity" EXACT [EC:2.6.1.58] synonym: "L-phenylalanine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.58] synonym: "phenylalanine (histidine) aminotransferase activity" EXACT [EC:2.6.1.58] synonym: "phenylalanine(histidine) aminotransferase activity" EXACT [] synonym: "phenylalanine(histidine):pyruvate aminotransferase activity" EXACT [EC:2.6.1.58] xref: EC:2.6.1.58 xref: GO:0047312 xref: MetaCyc:2.6.1.58-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006624 name: aromatic-amino-acid-glyoxylate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid." [EC:2.6.1.60, MetaCyc:2.6.1.60-RXN] synonym: "aromatic-amino-acid--glyoxylate aminotransferase activity" EXACT [EC:2.6.1.60] synonym: "aromatic-amino-acid-glyoxylate aminotransferase activity" EXACT [] synonym: "aromatic-amino-acid:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.60] xref: EC:2.6.1.60 xref: GO:0047313 xref: MetaCyc:2.6.1.60-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006625 name: kynurenine-glyoxylate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: glyoxylate + kynurenine = L-glycine + 4-(2-aminophenyl)-2,4-dioxobutanoate." [EC:2.6.1.63, MetaCyc:2.6.1.63-RXN] synonym: "kynurenine--glyoxylate aminotransferase activity" EXACT [EC:2.6.1.63] synonym: "kynurenine-glyoxylate aminotransferase activity" EXACT [] synonym: "L-kynurenine:glyoxylate aminotransferase (cyclizing)" EXACT [EC:2.6.1.63] xref: EC:2.6.1.63 xref: GO:0047315 xref: MetaCyc:2.6.1.63-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006626 name: glutamine-phenylpyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: phenylpyruvate + L-glutamine = L-phenylalanine + 2-keto-glutaramate." [EC:2.6.1.64, MetaCyc:2.6.1.64-RXN] synonym: "glutamine transaminase K activity" RELATED [EC:2.6.1.64] synonym: "glutamine--phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.64] synonym: "glutamine-phenylpyruvate aminotransferase activity" EXACT [] synonym: "L-glutamine:phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.64] xref: EC:2.6.1.64 xref: GO:0047316 xref: MetaCyc:2.6.1.64-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006627 name: N6-acetyl-beta-lysine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate." [EC:2.6.1.65, MetaCyc:2.6.1.65-RXN] synonym: "6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.65] synonym: "epsilon-acetyl-beta-lysine aminotransferase activity" EXACT [EC:2.6.1.65] synonym: "N(6)-acetyl-beta-lysine aminotransferase activity" EXACT [EC:2.6.1.65] synonym: "N6-acetyl-beta-lysine aminotransferase activity" EXACT [] xref: EC:2.6.1.65 xref: GO:0047317 xref: MetaCyc:2.6.1.65-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006628 name: aspartate-phenylpyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetic acid." [EC:2.6.1.70, MetaCyc:2.6.1.70-RXN] synonym: "aspartate--phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.70] synonym: "aspartate-phenylpyruvate aminotransferase activity" EXACT [] synonym: "L-aspartate:phenylpyruvate aminotransferase activity" EXACT [EC:2.6.1.70] xref: EC:2.6.1.70 xref: GO:0047319 xref: MetaCyc:2.6.1.70-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006629 name: D-4-hydroxyphenylglycine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = L-glutamate + 4-hydroxyphenylglyoxylate." [EC:2.6.1.72, MetaCyc:2.6.1.72-RXN] synonym: "D-4-hydroxyphenylglycine aminotransferase activity" EXACT [] synonym: "D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.72] synonym: "D-hydroxyphenylglycine aminotransferase activity" EXACT [EC:2.6.1.72] xref: EC:2.6.1.72 xref: GO:0047320 xref: MetaCyc:2.6.1.72-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006630 name: diphosphate-protein phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: microsomal-membrane protein + diphosphate = pyrophosphate + O-phospho-microsomal-membrane protein." [EC:2.7.99.1, MetaCyc:2.7.99.1-RXN] synonym: "diphosphate:microsomal-membrane-protein O-phosphotransferase activity" BROAD [EC:2.7.99.1] synonym: "DiPPT" RELATED [EC:2.7.99.1] synonym: "pyrophosphate-protein phosphotransferase activity" EXACT [EC:2.7.99.1] synonym: "pyrophosphate:protein phosphotransferase activity" EXACT [EC:2.7.99.1] synonym: "triphosphate-protein phosphotransferase activity" EXACT [EC:2.7.99.1] synonym: "triphosphate:microsomal-membrane-protein phosphotransferase activity" EXACT [EC:2.7.99.1] xref: EC:2.7.99.1 xref: GO:0047321 xref: MetaCyc:2.7.99.1-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006633 name: phosphoenolpyruvate-glycerone phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: dihydroxy-acetone + phosphoenolpyruvate = dihydroxy-acetone-phosphate + pyruvate." [EC:2.7.1.121, MetaCyc:2.7.1.121-RXN] synonym: "phosphoenolpyruvate:glycerone phosphotransferase activity" EXACT [EC:2.7.1.121] xref: EC:2.7.1.121 xref: GO:0047324 xref: MetaCyc:2.7.1.121-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006634 name: inositol tetrakisphosphate 1-kinase activity namespace: molecular_function def: "Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP." [EC:2.7.1.134, MetaCyc:2.7.1.134-RXN] synonym: "1D-myo-inositol-tetrakisphosphate 1-kinase activity" EXACT [EC:2.7.1.134] synonym: "1D-myo-inositol-trisphosphate 5-kinase activity" RELATED [EC:2.7.1.134] synonym: "1D-myo-inositol-trisphosphate 6-kinase activity" RELATED [EC:2.7.1.134] synonym: "ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.134] synonym: "ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.134] synonym: "ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.134] synonym: "inositol 3,4,5,6-tetrakisphosphate 1-kinase activity" EXACT [] synonym: "inositol-tetrakisphosphate 1-kinase activity" EXACT [] synonym: "inositol-trisphosphate 5-kinase activity" RELATED [EC:2.7.1.134] synonym: "inositol-trisphosphate 6-kinase activity" RELATED [EC:2.7.1.134] xref: EC:2.7.1.134 xref: GO:0047325 xref: MetaCyc:2.7.1.134-RXN is_a: CCO:F0008190 ! inositol tetrakisphosphate kinase activity [Term] id: CCO:F0006635 name: inositol tetrakisphosphate 5-kinase activity namespace: molecular_function def: "Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP." [EC:2.7.1.140, MetaCyc:2.7.1.140-RXN] synonym: "1D-myo-inositol-tetrakisphosphate 5-kinase activity" EXACT [] synonym: "ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase activity" EXACT [EC:2.7.1.140] synonym: "inositol 1,3,4,6-tetrakisphosphate 5-kinase activity" EXACT [] synonym: "inositol-tetrakisphosphate 5-kinase activity" EXACT [] xref: EC:2.7.1.140 xref: GO:0047326 xref: MetaCyc:2.7.1.140-RXN is_a: CCO:F0008190 ! inositol tetrakisphosphate kinase activity [Term] id: CCO:F0006636 name: glycerol-3-phosphate-glucose phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-glucose + glycerol-3-phosphate = glucose-6-phosphate + glycerol." [EC:2.7.1.142, MetaCyc:2.7.1.142-RXN] synonym: "sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.142] xref: EC:2.7.1.142 xref: GO:0047327 xref: MetaCyc:2.7.1.142-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006637 name: acyl-phosphate-hexose phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid." [EC:2.7.1.61, MetaCyc:2.7.1.61-RXN] synonym: "acyl-phosphate:D-hexose phosphotransferase activity" EXACT [EC:2.7.1.61] synonym: "hexose phosphate:hexose phosphotransferase activity" EXACT [EC:2.7.1.61] xref: EC:2.7.1.61 xref: GO:0047328 xref: MetaCyc:2.7.1.61-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006638 name: phosphoramidate-hexose phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3." [EC:2.7.1.62, MetaCyc:2.7.1.62-RXN] synonym: "phosphoramidate-hexose transphosphorylase activity" EXACT [EC:2.7.1.62] synonym: "phosphoramidate:hexose 1-phosphotransferase activity" EXACT [EC:2.7.1.62] synonym: "phosphoramidic-hexose transphosphorylase activity" EXACT [EC:2.7.1.62] xref: EC:2.7.1.62 xref: GO:0047329 xref: MetaCyc:2.7.1.62-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006639 name: polyphosphate-glucose phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate." [EC:2.7.1.63, MetaCyc:2.7.1.63-RXN] subset: gosubset_prok synonym: "polyphosphate glucokinase activity" EXACT [EC:2.7.1.63] synonym: "polyphosphate-D-(+)-glucose-6-phosphotransferase activity" EXACT [EC:2.7.1.63] synonym: "polyphosphate-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.63] synonym: "polyphosphate:D-glucose 6-phosphotransferase activity" EXACT [EC:2.7.1.63] xref: EC:2.7.1.63 xref: GO:0047330 xref: MetaCyc:2.7.1.63-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006640 name: diphosphate-glycerol phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol + pyrophosphate = phosphate + glycerol-3-phosphate." [EC:2.7.1.79, MetaCyc:2.7.1.79-RXN] synonym: "diphosphate:glycerol 1-phosphotransferase activity" EXACT [EC:2.7.1.79] synonym: "PPi-glycerol phosphotransferase activity" EXACT [EC:2.7.1.79] synonym: "pyrophosphate--glycerol phosphotransferase activity" EXACT [EC:2.7.1.79] xref: EC:2.7.1.79 xref: GO:0047331 xref: MetaCyc:2.7.1.79-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006641 name: diphosphate-serine phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine + pyrophosphate = phosphate + 3-phospho-serine." [EC:2.7.1.80, MetaCyc:2.7.1.80-RXN] synonym: "diphosphate:L-serine O-phosphotransferase activity" EXACT [EC:2.7.1.80] synonym: "pyrophosphate--serine phosphotransferase activity" EXACT [EC:2.7.1.80] synonym: "pyrophosphate-L-serine phosphotransferase activity" EXACT [EC:2.7.1.80] xref: EC:2.7.1.80 xref: GO:0047332 xref: MetaCyc:2.7.1.80-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006642 name: dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity namespace: molecular_function def: "Catalysis of the reaction: dihydrostreptomycin 6-phosphate + ATP = dihydrostreptomycin 3'-alpha-6-bisphosphate + ADP." [EC:2.7.1.88, MetaCyc:2.7.1.88-RXN] synonym: "ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase activity" EXACT [EC:2.7.1.88] synonym: "ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase activity" EXACT [EC:2.7.1.88] synonym: "dihydrostreptomycin 6-phosphate kinase (phosphorylating)" EXACT [EC:2.7.1.88] synonym: "dihydrostreptomycin-6-phosphate 3'alpha-kinase activity" EXACT [EC:2.7.1.88] xref: EC:2.7.1.88 xref: GO:0047333 xref: MetaCyc:2.7.1.88-RXN is_a: CCO:F0005515 ! aminoglycoside phosphotransferase activity [Term] id: CCO:F0006643 name: diphosphate-fructose-6-phosphate 1-phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: fructose-6-phosphate + pyrophosphate = phosphate + fructose-1,6-bisphosphate." [EC:2.7.1.90, MetaCyc:2.7.1.90-RXN] subset: gosubset_prok synonym: "6-phosphofructokinase (diphosphate) activity" EXACT [EC:2.7.1.90] synonym: "6-phosphofructokinase (pyrophosphate) activity" EXACT [EC:2.7.1.90] synonym: "diphosphate-dependent 6-phosphofructose-1-kinase activity" EXACT [EC:2.7.1.90] synonym: "diphosphate:D-fructose-6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.90] synonym: "inorganic pyrophosphate-dependent phosphofructokinase activity" EXACT [EC:2.7.1.90] synonym: "inorganic pyrophosphate-phosphofructokinase activity" EXACT [EC:2.7.1.90] synonym: "pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.90] synonym: "pyrophosphate-dependent 6-phosphofructose-1-kinase activity" EXACT [EC:2.7.1.90] synonym: "pyrophosphate-dependent phosphofructo-1-kinase activity" EXACT [EC:2.7.1.90] synonym: "pyrophosphate-fructose 6-phosphate phosphotransferase activity" EXACT [EC:2.7.1.90] xref: EC:2.7.1.90 xref: GO:0047334 xref: MetaCyc:2.7.1.90-RXN is_a: CCO:F0001906 ! phosphofructokinase activity [Term] id: CCO:F0006644 name: 3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate." [EC:2.7.4.17, MetaCyc:2.7.4.17-RXN] synonym: "1,3-diphosphoglycerate-polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.17] synonym: "3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.17] synonym: "diphosphoglycerate-polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.17] xref: EC:2.7.4.17 xref: GO:0047335 xref: MetaCyc:2.7.4.17-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0006645 name: 5-methyldeoxycytidine-5'-phosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: deoxy-5-methylcytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP." [EC:2.7.4.19, MetaCyc:2.7.4.19-RXN] synonym: "ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase activity" EXACT [EC:2.7.4.19] xref: EC:2.7.4.19 xref: GO:0047336 xref: MetaCyc:2.7.4.19-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0006646 name: dolichyl-diphosphate-polyphosphate phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate." [EC:2.7.4.20, MetaCyc:2.7.4.20-RXN] synonym: "dolichyl-diphosphate:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.20] synonym: "dolichylpyrophosphate:polyphosphate phosphotransferase activity" EXACT [EC:2.7.4.20] xref: EC:2.7.4.20 xref: GO:0047337 xref: MetaCyc:2.7.4.20-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0006647 name: UTP:xylose-1-phosphate uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate." [EC:2.7.7.11, MetaCyc:2.7.7.11-RXN] synonym: "UDP-xylose pyrophosphorylase activity" EXACT [EC:2.7.7.11] synonym: "uridine diphosphoxylose pyrophosphorylase activity" EXACT [EC:2.7.7.11] synonym: "uridylyltransferase, xylose 1-phosphate" EXACT [EC:2.7.7.11] synonym: "UTP-xylose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] synonym: "UTP:alpha-D-xylose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] synonym: "xylose 1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] synonym: "xylose-1-phosphate uridylyltransferase activity" EXACT [EC:2.7.7.11] xref: EC:2.7.7.11 xref: GO:0047338 xref: MetaCyc:2.7.7.11-RXN is_a: CCO:F0008184 ! UTP-monosaccharide-1-phosphate uridylyltransferase activity [Term] id: CCO:F0006648 name: nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate." [EC:2.7.7.28, MetaCyc:2.7.7.28-RXN] synonym: "GDP hexose pyrophosphorylase activity" NARROW [EC:2.7.7.28] synonym: "GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity" NARROW [EC:2.7.7.28] synonym: "GTP:hexose-1-phosphate guanylyltransferase activity" NARROW [] synonym: "guanosine diphosphohexose pyrophosphorylase activity" NARROW [EC:2.7.7.28] synonym: "hexose 1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.28] synonym: "hexose 1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] synonym: "hexose nucleotidylating enzyme activity" EXACT [EC:2.7.7.28] synonym: "hexose-1-phosphate guanylyltransferase activity" NARROW [] synonym: "NDP hexose pyrophosphorylase activity" EXACT [EC:2.7.7.28] synonym: "NDP-hexose diphosphorylase activity" EXACT [] synonym: "NDP-hexose pyrophosphorylase activity" EXACT [] synonym: "NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] synonym: "NTP:hexose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] synonym: "nucleoside diphosphohexose pyrophosphorylase activity" EXACT [EC:2.7.7.28] synonym: "nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.28] xref: EC:2.7.7.28 xref: GO:0047339 xref: GO:0047340 xref: MetaCyc:2.7.7.28-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006649 name: fucose-1-phosphate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-fucose 1-phosphate + GTP = guanosine diphosphate fucose + diphosphate." [EC:2.7.7.30, MetaCyc:2.7.7.30-RXN] synonym: "GDP fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] synonym: "GDP-fucose diphosphorylase activity" EXACT [EC:2.7.7.30] synonym: "GDP-fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] synonym: "GDP-L-fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] synonym: "GTP:beta-L-fucose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.30] synonym: "GTP:fucose-1-phosphate guanylyltransferase activity" EXACT [] synonym: "GTP:L-fucose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.30] synonym: "guanosine diphosphate L-fucose pyrophosphorylase activity" EXACT [EC:2.7.7.30] xref: EC:2.7.7.30 xref: GO:0047341 xref: MetaCyc:2.7.7.30-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006650 name: galactose-1-phosphate thymidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-D-galactose-1-phosphate + dTTP = dTDP-D-galactose + diphosphate." [EC:2.7.7.32, MetaCyc:2.7.7.32-RXN] synonym: "dTDP galactose pyrophosphorylase activity" EXACT [EC:2.7.7.32] synonym: "dTDP-galactose diphosphorylase activity" EXACT [EC:2.7.7.32] synonym: "dTDP-galactose pyrophosphorylase activity" EXACT [EC:2.7.7.32] synonym: "dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.32] synonym: "galactose 1-phosphate thymidylyl transferase activity" EXACT [EC:2.7.7.32] synonym: "thymidine diphosphogalactose pyrophosphorylase activity" EXACT [EC:2.7.7.32] synonym: "thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity" EXACT [EC:2.7.7.32] xref: EC:2.7.7.32 xref: GO:0047342 xref: MetaCyc:2.7.7.32-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006651 name: glucose-1-phosphate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glucose-1-phosphate + CTP = CDP-D-glucose + diphosphate." [EC:2.7.7.33, MetaCyc:2.7.7.33-RXN] subset: gosubset_prok synonym: "CDP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] synonym: "CDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.33] synonym: "CDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] synonym: "CTP:alpha-D-glucose-1-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.33] synonym: "CTP:D-glucose-1-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.33] synonym: "CTP:glucose-1-phosphate cytidylyltransferase activity" EXACT [] synonym: "cytidine diphosphate glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] synonym: "cytidine diphosphate-D-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] synonym: "cytidine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.33] xref: EC:2.7.7.33 xref: GO:0047343 xref: MetaCyc:2.7.7.33-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006652 name: glucose-1-phosphate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glucose-1-phosphate + GTP = GDP-D-glucose + diphosphate." [EC:2.7.7.34, MetaCyc:2.7.7.34-RXN] synonym: "GDP glucose pyrophosphorylase activity" EXACT [EC:2.7.7.34] synonym: "GDP-glucose diphosphorylase activity" EXACT [EC:2.7.7.34] synonym: "GDP-glucose pyrophosphorylase activity" EXACT [EC:2.7.7.34] synonym: "GTP:alpha-D-glucose-1-phosphate guanylyltransferase activity" EXACT [EC:2.7.7.34] synonym: "GTP:glucose-1-phosphate guanylyltransferase activity" EXACT [] synonym: "guanosine diphosphoglucose pyrophosphorylase activity" EXACT [EC:2.7.7.34] xref: EC:2.7.7.34 xref: GO:0047344 xref: MetaCyc:2.7.7.34-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006653 name: ribose-5-phosphate adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ribose-5-phosphate + ADP = phosphate + adenosine diphosphate ribose." [EC:2.7.7.35, MetaCyc:2.7.7.35-RXN] synonym: "adenosine diphosphoribose phosphorylase activity" EXACT [EC:2.7.7.35] synonym: "ADP ribose phosphorylase activity" EXACT [EC:2.7.7.35] synonym: "ADP-ribose phosphorylase activity" EXACT [EC:2.7.7.35] synonym: "ADP:D-ribose-5-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.35] synonym: "ADP:ribose-5-phosphate adenylyltransferase activity" EXACT [] xref: EC:2.7.7.35 xref: GO:0047345 xref: MetaCyc:2.7.7.35-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006654 name: aldose-1-phosphate adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose." [EC:2.7.7.36, MetaCyc:2.7.7.36-RXN] synonym: "adenosine diphosphate glucose:orthophosphate adenylyltransferase activity" EXACT [EC:2.7.7.36] synonym: "adenosine diphosphosugar phosphorylase activity" EXACT [EC:2.7.7.36] synonym: "ADP sugar phosphorylase activity" EXACT [EC:2.7.7.36] synonym: "ADP-aldose phosphorylase activity" EXACT [EC:2.7.7.36] synonym: "ADP-sugar phosphorylase activity" BROAD [EC:2.7.7.36] synonym: "ADP:aldose-1-phosphate adenylyltransferase activity" EXACT [] synonym: "ADP:alpha-D-aldose-1-phosphate adenylyltransferase activity" EXACT [EC:2.7.7.36] synonym: "ADPaldose phosphorylase activity" EXACT [EC:2.7.7.36] synonym: "sugar-1-phosphate adenylyltransferase activity" BROAD [EC:2.7.7.36] xref: EC:2.7.7.36 xref: GO:0047346 xref: MetaCyc:2.7.7.36-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006655 name: aldose-1-phosphate nucleotidyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose." [EC:2.7.7.37, MetaCyc:2.7.7.37-RXN] subset: gosubset_prok synonym: "glucose 1-phosphate inosityltransferase activity" EXACT [EC:2.7.7.37] synonym: "NDP sugar phosphorylase activity" EXACT [EC:2.7.7.37] synonym: "NDP-aldose phosphorylase activity" EXACT [EC:2.7.7.37] synonym: "NDP-sugar phosphorylase activity" BROAD [EC:2.7.7.37] synonym: "NDP:aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] synonym: "NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] synonym: "NDPaldose phosphorylase activity" EXACT [EC:2.7.7.37] synonym: "nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] synonym: "nucleoside diphosphosugar phosphorylase activity" EXACT [EC:2.7.7.37] synonym: "sugar nucleotide phosphorylase activity" EXACT [EC:2.7.7.37] synonym: "sugar phosphate nucleotidyltransferase activity" EXACT [EC:2.7.7.37] synonym: "sugar-1-phosphate nucleotidyltransferase activity" BROAD [EC:2.7.7.37] xref: EC:2.7.7.37 xref: GO:0047347 xref: MetaCyc:2.7.7.37-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006656 name: glycerol-3-phosphate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol-3-phosphate + CTP = CDPglycerol + diphosphate." [EC:2.7.7.39, MetaCyc:2.7.7.39-RXN] subset: gosubset_prok synonym: "CDP-glycerol diphosphorylase activity" EXACT [EC:2.7.7.39] synonym: "CDP-glycerol pyrophosphorylase activity" EXACT [EC:2.7.7.39] synonym: "CTP:glycerol 3-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.39] synonym: "CTP:glycerol-3-phosphate cytidylyltransferase activity" EXACT [] synonym: "CTP:sn-glycerol-3-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.39] synonym: "cytidine diphosphate glycerol pyrophosphorylase activity" EXACT [EC:2.7.7.39] synonym: "cytidine diphosphoglycerol pyrophosphorylase activity" EXACT [EC:2.7.7.39] synonym: "Gro-PCT" RELATED [EC:2.7.7.39] xref: EC:2.7.7.39 xref: GO:0047348 xref: MetaCyc:2.7.7.39-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006657 name: D-ribitol-5-phosphate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate." [EC:2.7.7.40, MetaCyc:2.7.7.40-RXN] subset: gosubset_prok synonym: "CDP ribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] synonym: "CDP-ribitol diphosphorylase activity" EXACT [EC:2.7.7.40] synonym: "CDP-ribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] synonym: "CTP:D-ribitol-5-phosphate cytidylyltransferase activity" EXACT [] synonym: "cytidine diphosphate ribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] synonym: "cytidine diphosphoribitol pyrophosphorylase activity" EXACT [EC:2.7.7.40] synonym: "ribitol 5-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.40] xref: EC:2.7.7.40 xref: GO:0047349 xref: MetaCyc:2.7.7.40-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006658 name: glucuronate-1-phosphate uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = UDP-D-glucuronate + diphosphate." [EC:2.7.7.44, MetaCyc:2.7.7.44-RXN] synonym: "UDP-D-glucuronic acid pyrophosphorylase activity" EXACT [EC:2.7.7.44] synonym: "UDP-glucuronate pyrophosphorylase activity" EXACT [EC:2.7.7.44] synonym: "UDP-glucuronic acid pyrophosphorylase activity" EXACT [EC:2.7.7.44] synonym: "uridine diphosphoglucuronic pyrophosphorylase activity" EXACT [EC:2.7.7.44] synonym: "UTP:1-phospho-alpha-D-glucuronate uridylyltransferase activity" EXACT [EC:2.7.7.44] synonym: "UTP:glucuronate-1-phosphate uridylyltransferase activity" EXACT [] xref: EC:2.7.7.44 xref: GO:0047350 xref: MetaCyc:2.7.7.44-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006659 name: guanosine-triphosphate guanylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 GTP = P1,P4-bis(5'-guanosyl) tetraphosphate + diphosphate." [EC:2.7.7.45, MetaCyc:2.7.7.45-RXN] synonym: "GTP:GTP guanylyltransferase activity" EXACT [] xref: EC:2.7.7.45 xref: GO:0047351 xref: MetaCyc:2.7.7.45-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006660 name: adenylylsulfate-ammonia adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: NH3 + APS = SO4(2-) (sulfate) + adenosine 5'-phosphoramidate." [EC:2.7.7.51, MetaCyc:2.7.7.51-RXN] synonym: "adenylylsulfate:ammonia adenylyltransferase activity" EXACT [EC:2.7.7.51] synonym: "adenylylsulphate-ammonia adenylyltransferase activity" EXACT [] synonym: "APSAT" RELATED [EC:2.7.7.51] xref: EC:2.7.7.51 xref: GO:0047352 xref: MetaCyc:2.7.7.51-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006661 name: N-methylphosphoethanolamine cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamin + diphosphate." [EC:2.7.7.57, MetaCyc:2.7.7.57-RXN] synonym: "CTP:N-methylethanolamine-phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.57] synonym: "CTP:N-methylphosphoethanolamine cytidylyltransferase activity" EXACT [] synonym: "CTP:P-MEA cytidylyltransferase activity" EXACT [EC:2.7.7.57] synonym: "monomethylethanolamine phosphate cytidylyltransferase activity" EXACT [EC:2.7.7.57] xref: EC:2.7.7.57 xref: GO:0047353 xref: MetaCyc:2.7.7.57-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006662 name: sphingosine cholinephosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: sphingosine + CDP-choline = sphingosyl-phosphocholine + CMP." [EC:2.7.8.10, MetaCyc:2.7.8.10-RXN] synonym: "CDP-choline-sphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.10] synonym: "CDP-choline:sphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.10] synonym: "cytidine diphosphocholine-sphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.10] synonym: "phosphorylcholine-sphingosine transferase activity" EXACT [EC:2.7.8.10] synonym: "sphingosine choline phosphotransferase activity" EXACT [] xref: EC:2.7.8.10 xref: GO:0047354 xref: MetaCyc:2.7.8.10-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006663 name: CDP-glycerol glycerophosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP." [EC:2.7.8.12, MetaCyc:2.7.8.12-RXN] subset: gosubset_prok synonym: "CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase activity" EXACT [EC:2.7.8.12] synonym: "CDPglycerol glycerophosphotransferase activity" EXACT [EC:2.7.8.12] synonym: "CGPTase activity" EXACT [EC:2.7.8.12] synonym: "cytidine diphosphoglycerol glycerophosphotransferase activity" EXACT [EC:2.7.8.12] synonym: "glycerophosphate synthetase activity" EXACT [EC:2.7.8.12] synonym: "poly(glycerol phosphate) polymerase activity" EXACT [EC:2.7.8.12] synonym: "teichoic acid glycerol transferase activity" EXACT [EC:2.7.8.12] synonym: "teichoic-acid synthase activity" BROAD [EC:2.7.8.12] xref: EC:2.7.8.12 xref: GO:0047355 xref: MetaCyc:2.7.8.12-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006664 name: CDP-ribitol ribitolphosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP." [EC:2.7.8.14, MetaCyc:2.7.8.14-RXN] subset: gosubset_prok synonym: "CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity" EXACT [EC:2.7.8.14] synonym: "CDPribitol ribitolphosphotransferase activity" EXACT [EC:2.7.8.14] synonym: "poly(ribitol phosphate) synthetase activity" EXACT [EC:2.7.8.14] synonym: "polyribitol phosphate polymerase activity" EXACT [EC:2.7.8.14] synonym: "polyribitol phosphate synthetase activity" EXACT [EC:2.7.8.14] synonym: "teichoate synthase activity" EXACT [EC:2.7.8.14] synonym: "teichoate synthetase activity" EXACT [EC:2.7.8.14] synonym: "teichoic-acid synthase activity" BROAD [EC:2.7.8.14] xref: EC:2.7.8.14 xref: GO:0047356 xref: MetaCyc:2.7.8.14-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006665 name: UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + UDP-galactose = UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP." [EC:2.7.8.18, MetaCyc:2.7.8.18-RXN] synonym: "galactose-1-phosphotransferase activity" EXACT [EC:2.7.8.18] synonym: "galactosyl phosphotransferase activity" EXACT [EC:2.7.8.18] synonym: "UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity" EXACT [EC:2.7.8.18] synonym: "UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity" EXACT [EC:2.7.8.18] synonym: "UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity" EXACT [EC:2.7.8.18] synonym: "uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity" EXACT [EC:2.7.8.18] xref: EC:2.7.8.18 xref: GO:0047357 xref: MetaCyc:2.7.8.18-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006666 name: UDP-glucose-glycoprotein glucose phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP." [EC:2.7.8.19, MetaCyc:2.7.8.19-RXN] synonym: "Glc-phosphotransferase activity" EXACT [EC:2.7.8.19] synonym: "GlcPTase activity" EXACT [EC:2.7.8.19] synonym: "UDP-glucose:glycoprotein glucose-1-phosphotransferase activity" EXACT [EC:2.7.8.19] synonym: "UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase activity" EXACT [EC:2.7.8.19] synonym: "UDPglucose-glycoprotein glucose phosphotransferase activity" EXACT [EC:2.7.8.19] synonym: "UDPglucose:glycoprotein-D-mannose glucosephosphotransferase activity" EXACT [EC:2.7.8.19] synonym: "uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity" EXACT [EC:2.7.8.19] xref: EC:2.7.8.19 xref: GO:0047358 xref: MetaCyc:2.7.8.19-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006667 name: 1-alkenyl-2-acylglycerol choline phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP." [EC:2.7.8.22, MetaCyc:2.7.8.22-RXN] synonym: "CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase activity" EXACT [EC:2.7.8.22] synonym: "CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase activity" EXACT [EC:2.7.8.22] xref: EC:2.7.8.22 xref: GO:0047359 xref: MetaCyc:2.7.8.22-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006668 name: undecaprenyl-phosphate galactose phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: undecaprenyl phosphate + UDP-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP." [EC:2.7.8.6, MetaCyc:2.7.8.6-RXN] subset: gosubset_prok synonym: "poly(isoprenol)-phosphate galactose phosphotransferase activity" EXACT [EC:2.7.8.6] synonym: "poly(isoprenol)-phosphate galactosephosphotransferase activity" EXACT [EC:2.7.8.6] synonym: "Poly(isoprenol)-phosphate galactosephosphotransferase activity" EXACT [EC:2.7.8.6] synonym: "poly(isoprenyl)phosphate galactosephosphatetransferase activity" EXACT [EC:2.7.8.6] synonym: "UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity" EXACT [EC:2.7.8.6] synonym: "undecaprenyl phosphate galactosyl-1-phosphate transferase activity" EXACT [EC:2.7.8.6] xref: EC:2.7.8.6 xref: GO:0047360 xref: MetaCyc:2.7.8.6-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006669 name: phosphomannan mannosephosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP." [EC:2.7.8.9, MetaCyc:2.7.8.9-RXN] synonym: "GDP-mannose:phosphomannan mannose phosphotransferase activity" EXACT [EC:2.7.8.9] xref: EC:2.7.8.9 xref: GO:0047361 xref: MetaCyc:2.7.8.9-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006670 name: thiosulfate-dithiol sulfurtransferase activity namespace: molecular_function def: "Catalysis of the reaction: dithioerythritol + S2O3(2-) (thiosulfate) = H2S + dithioerythritol disulfide + SO3(2-) (sulfite)." [EC:2.8.1.5, MetaCyc:2.8.1.5-RXN] synonym: "thiosulfate reductase activity" EXACT [EC:2.8.1.5] synonym: "thiosulfate:dithioerythritol sulfurtransferase activity" EXACT [EC:2.8.1.5] synonym: "thiosulphate-dithiol sulphurtransferase activity" EXACT [] synonym: "TSR" RELATED [EC:2.8.1.5] xref: EC:2.8.1.5 xref: GO:0047362 xref: MetaCyc:2.8.1.5-RXN is_a: CCO:F0003355 ! sulfurtransferase activity [Term] id: CCO:F0006671 name: triglucosylalkylacylglycerol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate." [EC:2.8.2.19, MetaCyc:2.8.2.19-RXN] synonym: "3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase activity" EXACT [EC:2.8.2.19] synonym: "triglucosylalkylacylglycerol sulphotransferase activity" EXACT [] synonym: "triglucosylmonoalkylmonoacyl sulfotransferase activity" EXACT [EC:2.8.2.19] xref: EC:2.8.2.19 xref: GO:0047363 xref: MetaCyc:2.8.2.19-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006672 name: desulfoglucosinolate sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: desulfoglucotropeolin + 3'-phosphoadenosine 5'-phosphosulfate = glucotropeolin + adenosine 3',5'-bisphosphate." [EC:2.8.2.24, MetaCyc:2.8.2.24-RXN] synonym: "3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase activity" EXACT [EC:2.8.2.24] synonym: "3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase activity" EXACT [EC:2.8.2.24] synonym: "desulphoglucosinolate sulphotransferase activity" EXACT [] synonym: "PAPS-desulfoglucosinolate sulfotransferase activity" EXACT [EC:2.8.2.24] xref: EC:2.8.2.24 xref: GO:0047364 xref: MetaCyc:2.8.2.24-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006673 name: quercetin-3-sulfate 3'-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: quercetin 3-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3'-bissulfate + adenosine 3',5'-bisphosphate." [EC:2.8.2.26, MetaCyc:2.8.2.26-RXN] synonym: "3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 3'-sulfotransferase activity" EXACT [EC:2.8.2.26] synonym: "3'-sulfotransferase activity" EXACT [EC:2.8.2.26] synonym: "flavonol 3'-sulfotransferase activity" EXACT [EC:2.8.2.26] synonym: "PAPS:flavonol 3-sulfate 3'-sulfotransferase activity" EXACT [EC:2.8.2.26] synonym: "quercetin-3-sulphate 3'-sulphotransferase activity" EXACT [] xref: EC:2.8.2.26 xref: GO:0047365 xref: MetaCyc:2.8.2.26-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006674 name: quercetin-3-sulfate 4'-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: quercetin 3-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,4'-bissulfate + adenosine 3',5'-bisphosphate." [EC:2.8.2.27, MetaCyc:2.8.2.27-RXN] synonym: "3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 4'-sulfotransferase activity" EXACT [EC:2.8.2.27] synonym: "flavonol 4'-sulfotransferase activity" EXACT [EC:2.8.2.27] synonym: "PAPS:flavonol 3-sulfate 4'-sulfotransferase activity" EXACT [EC:2.8.2.27] synonym: "quercetin-3-sulphate 4'-sulphotransferase activity" EXACT [] xref: EC:2.8.2.27 xref: GO:0047366 xref: MetaCyc:2.8.2.27-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006675 name: quercetin-3,3'-bissulfate 7-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate." [EC:2.8.2.28, MetaCyc:2.8.2.28-RXN] synonym: "3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase activity" EXACT [EC:2.8.2.28] synonym: "7-sulfotransferase activity" EXACT [EC:2.8.2.28] synonym: "flavonol 7-sulfotransferase activity" EXACT [EC:2.8.2.28] synonym: "PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity" EXACT [EC:2.8.2.28] synonym: "quercetin-3,3'-bissulphate 7-sulphotransferase activity" EXACT [] xref: EC:2.8.2.28 xref: GO:0047367 xref: MetaCyc:2.8.2.28-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006676 name: UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine 4-sulfate + 3'-phosphoadenosine 5'-phosphosulfate = UDP-N-acetyl-D-galactosamine 4,6-bissulfate + adenosine 3',5'-bisphosphate." [EC:2.8.2.7, MetaCyc:2.8.2.7-RXN] synonym: "3'-phosphoadenylyl-sulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase activity" EXACT [EC:2.8.2.7] synonym: "UDP-N-acetylgalactosamine-4-sulphate sulphotransferase activity" EXACT [] synonym: "uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity" EXACT [EC:2.8.2.7] synonym: "uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity" EXACT [EC:2.8.2.7] xref: EC:2.8.2.7 xref: GO:0047368 xref: MetaCyc:2.8.2.7-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006677 name: succinate-hydroxymethylglutarate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate." [EC:2.8.3.13, MetaCyc:2.8.3.13-RXN] synonym: "dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity" EXACT [EC:2.8.3.13] synonym: "hydroxymethylglutarate coenzyme A-transferase activity" EXACT [EC:2.8.3.13] synonym: "succinate:(S)-3-hydroxy-3-methylglutarate CoA-transferase activity" EXACT [EC:2.8.3.13] xref: EC:2.8.3.13 xref: GO:0047369 xref: MetaCyc:2.8.3.13-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0006678 name: succinate-citramalate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate." [EC:2.8.3.7, MetaCyc:2.8.3.7-RXN] synonym: "citramalate coenzyme A-transferase activity" EXACT [EC:2.8.3.7] synonym: "itaconate CoA-transferase activity" EXACT [EC:2.8.3.7] synonym: "succinyl coenzyme A-citramalyl coenzyme A transferase activity" EXACT [EC:2.8.3.7] synonym: "succinyl-CoA:citramalate CoA-transferase activity" EXACT [EC:2.8.3.7] xref: EC:2.8.3.7 xref: GO:0047370 xref: MetaCyc:2.8.3.7-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0006679 name: butyrate-acetoacetate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acetoacetate + butyryl-CoA = acetoacetyl-CoA + butyrate." [EC:2.8.3.9, MetaCyc:2.8.3.9-RXN] subset: gosubset_prok synonym: "butanoyl-CoA:acetoacetate CoA-transferase activity" EXACT [EC:2.8.3.9] synonym: "butyryl coenzyme A-acetoacetate coenzyme A-transferase activity" EXACT [EC:2.8.3.9] synonym: "butyryl-CoA-acetoacetate CoA-transferase activity" EXACT [EC:2.8.3.9] xref: EC:2.8.3.9 xref: GO:0047371 xref: MetaCyc:2.8.3.9-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0006680 name: acylglycerol lipase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol." [EC:3.1.1.23, MetaCyc:3.1.1.23-RXN] subset: gosubset_prok synonym: "fatty acyl monoester lipase activity" EXACT [EC:3.1.1.23] synonym: "glycerol-ester acylhydrolase activity" EXACT [EC:3.1.1.23] synonym: "monoacylglycerol hydrolase activity" EXACT [EC:3.1.1.23] synonym: "monoacylglycerol lipase activity" EXACT [EC:3.1.1.23] synonym: "monoacylglycerolipase activity" EXACT [EC:3.1.1.23] synonym: "monoglyceridase activity" EXACT [EC:3.1.1.23] synonym: "monoglyceride hydrolase activity" EXACT [EC:3.1.1.23] synonym: "monoglyceride lipase activity" EXACT [EC:3.1.1.23] synonym: "monoglyceridyllipase activity" EXACT [EC:3.1.1.23] xref: EC:3.1.1.23 xref: GO:0047372 xref: MetaCyc:3.1.1.23-RXN xref: Reactome:83299 is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0003111 ! lipase activity [Term] id: CCO:F0006681 name: acetoxybutynylbithiophene deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 5-(4-acetoxybut-1-ynyl)-2-2'-bithiophene = acetate + 5-(4-hydroxybut-1-ynyl)-2,2'-bithiophene." [EC:3.1.1.54, MetaCyc:3.1.1.54-RXN] synonym: "5-(4-acetoxy-1-butynyl)-2,2'-bithiophene:acetate esterase activity" EXACT [EC:3.1.1.54] synonym: "5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase activity" EXACT [EC:3.1.1.54] synonym: "acetoxybutynylbithiophene esterase activity" EXACT [EC:3.1.1.54] xref: EC:3.1.1.54 xref: GO:0047373 xref: MetaCyc:3.1.1.54-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006682 name: methylumbelliferyl-acetate deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: 4-methylumbelliferyl acetate + H2O = acetate + 4-methylumbelliferone." [EC:3.1.1.56, MetaCyc:3.1.1.56-RXN] synonym: "4-methylumbelliferyl-acetate acylhydrolase activity" EXACT [EC:3.1.1.56] synonym: "esterase D activity" RELATED [EC:3.1.1.56] xref: EC:3.1.1.56 xref: GO:0047374 xref: MetaCyc:3.1.1.56-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006683 name: N-acetylgalactosaminoglycan deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan." [EC:3.1.1.58, MetaCyc:3.1.1.58-RXN] synonym: "N-acetyl galactosaminoglycan deacetylase activity" EXACT [EC:3.1.1.58] synonym: "N-acetyl-D-galactosaminoglycan acetylhydrolase activity" EXACT [EC:3.1.1.58] synonym: "polysaccharide deacetylase activity" EXACT [EC:3.1.1.58] synonym: "Vi-polysaccharide deacetylase activity" EXACT [EC:3.1.1.58] xref: EC:3.1.1.58 xref: GO:0047375 xref: MetaCyc:3.1.1.58-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006684 name: all-trans-retinyl-palmitate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + retinol-palmitate = palmitate + retinol." [EC:3.1.1.64, MetaCyc:3.1.1.64-RXN] synonym: "all-trans-retinyl-palmitate acylhydrolase activity" EXACT [EC:3.1.1.64] xref: EC:3.1.1.64 xref: GO:0047376 xref: MetaCyc:3.1.1.64-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006685 name: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene = acetate + 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene." [EC:3.1.1.66, MetaCyc:3.1.1.66-RXN] synonym: "3,4-diacetoxybutinylbithiophene:4-acetate esterase activity" EXACT [EC:3.1.1.66] synonym: "5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase activity" EXACT [EC:3.1.1.66] synonym: "diacetoxybutynylbithiophene acetate esterase activity" EXACT [EC:3.1.1.66] xref: EC:3.1.1.66 xref: GO:0047377 xref: MetaCyc:3.1.1.66-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006686 name: acetylalkylglycerol acetylhydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 2-acetyl-1-alkyl-sn-glycerol = acetate + 1-alkyl-sn-glycerol." [EC:3.1.1.71, MetaCyc:3.1.1.71-RXN] synonym: "2-acetyl-1-alkyl-sn-glycerol acetylhydrolase activity" EXACT [EC:3.1.1.71] synonym: "alkylacetylglycerol acetylhydrolase activity" EXACT [EC:3.1.1.71] xref: EC:3.1.1.71 xref: GO:0047378 xref: MetaCyc:3.1.1.71-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006687 name: ADP-dependent short-chain-acyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA." [EC:3.1.2.18, MetaCyc:3.1.2.18-RXN] synonym: "ADP-dependent-short-chain-acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] synonym: "propionyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18] synonym: "propionyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] synonym: "propionyl-CoA thioesterase activity" EXACT [EC:3.1.2.18] synonym: "short-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18] synonym: "short-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] synonym: "short-chain acyl-CoA thioesterase activity" EXACT [EC:3.1.2.18] xref: EC:3.1.2.18 xref: GO:0047379 xref: MetaCyc:3.1.2.18-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0006688 name: ADP-dependent medium-chain-acyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA." [EC:3.1.2.19, MetaCyc:3.1.2.19-RXN] subset: gosubset_prok synonym: "ADP-dependent-medium-chain-acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] synonym: "medium-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19] synonym: "medium-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] synonym: "medium-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19] synonym: "medium-chain hydrolase activity" EXACT [EC:3.1.2.19] synonym: "myristoyl-CoA thioesterase activity" EXACT [EC:3.1.2.19] xref: EC:3.1.2.19 xref: GO:0047380 xref: MetaCyc:3.1.2.19-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0006689 name: dodecanoyl-[acyl-carrier-protein] hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein]." [EC:3.1.2.21, MetaCyc:3.1.2.21-RXN] synonym: "dodecanoyl-[acyl-carrier protein] hydrolase activity" EXACT [] synonym: "dodecanoyl-ACP hydrolase activity" EXACT [] synonym: "dodecanoyl-acyl-carrier-protein hydrolase activity" EXACT [EC:3.1.2.21] synonym: "dodecyl-[acyl-carrier protein] hydrolase activity" EXACT [EC:3.1.2.21] synonym: "dodecyl-acyl-carrier protein hydrolase" BROAD [EC:3.1.2.21] synonym: "lauroyl-[acyl-carrier-protein] hydrolase activity" EXACT [] synonym: "lauroyl-ACP hydrolase activity" EXACT [] synonym: "lauryl-[acyl-carrier protein] hydrolase activity" EXACT [EC:3.1.2.21] synonym: "lauryl-acyl-carrier protein hydrolase activity" EXACT [EC:3.1.2.21] synonym: "lauryl-acyl-carrier-protein hydrolase activity" EXACT [EC:3.1.2.21] xref: EC:3.1.2.21 xref: GO:0016294 xref: GO:0047381 xref: MetaCyc:3.1.2.21-RXN is_a: CCO:F0003110 ! acyl-[acyl-carrier-protein] hydrolase activity [Term] id: CCO:F0006690 name: methylphosphothioglycerate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + S-methyl-3-phospho-1-thio-D-glycerate = phosphate + S-methyl-1-thio-D-glycerate." [EC:3.1.3.14, MetaCyc:3.1.3.14-RXN] synonym: "methylthiophosphoglycerate phosphatase activity" EXACT [EC:3.1.3.14] synonym: "S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity" EXACT [EC:3.1.3.14] xref: EC:3.1.3.14 xref: GO:0047382 xref: MetaCyc:3.1.3.14-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006691 name: guanidinodeoxy-scyllo-inositol-4-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate = phosphate + 1-guanidino-1-deoxy-scyllo-inositol." [EC:3.1.3.40, MetaCyc:3.1.3.40-RXN] synonym: "1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase activity" EXACT [EC:3.1.3.40] synonym: "1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase activity" EXACT [EC:3.1.3.40] synonym: "1-guanidino-scyllo-inositol 4-phosphatase activity" EXACT [EC:3.1.3.40] xref: EC:3.1.3.40 xref: GO:0047383 xref: MetaCyc:3.1.3.40-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006694 name: fructose-2,6-bisphosphate 6-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + D-fructose 2,6-bisphosphate = phosphate + fructose-2-phosphate." [EC:3.1.3.54, MetaCyc:3.1.3.54-RXN] synonym: "beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.54] synonym: "D-fructose-2,6-bisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.54] synonym: "fructose 2,6-bisphosphate-6-phosphohydrolase activity" EXACT [EC:3.1.3.54] synonym: "fructose-2,6-bisphosphate 6-phosphohydrolase activity" EXACT [EC:3.1.3.54] xref: EC:3.1.3.54 xref: GO:0047386 xref: MetaCyc:3.1.3.54-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006695 name: serine-ethanolaminephosphate phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + serine phosphoethanolamine = phosphoryl-ethanolamine + L-serine." [EC:3.1.4.13, MetaCyc:3.1.4.13-RXN] subset: gosubset_prok synonym: "SEP diesterase activity" EXACT [EC:3.1.4.13] synonym: "serine ethanolamine phosphodiester phosphodiesterase activity" EXACT [EC:3.1.4.13] synonym: "serine-phosphoethanolamine ethanolaminephosphohydrolase activity" EXACT [EC:3.1.4.13] xref: EC:3.1.4.13 xref: GO:0047387 xref: MetaCyc:3.1.4.13-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006696 name: adenylyl-[glutamate-ammonia ligase] hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + adenylyl-GS = glutaminesyn-oligomer + AMP." [EC:3.1.4.15, MetaCyc:3.1.4.15-RXN] synonym: "adenylyl(glutamine synthetase) hydrolase activity" EXACT [EC:3.1.4.15] synonym: "adenylyl-glutamate-ammonia ligase hydrolase activity" EXACT [EC:3.1.4.15] synonym: "adenylyl-glutamine-synthetasehydrolase activity" EXACT [EC:3.1.4.15] synonym: "adenylyl-L-glutamate:ammonia ligase (ADP-forming) adenylylhydrolase activity" EXACT [EC:3.1.4.15] xref: EC:3.1.4.15 xref: GO:0047388 xref: MetaCyc:3.1.4.15-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006697 name: glycerophosphocholine phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline." [EC:3.1.4.2, MetaCyc:3.1.4.2-RXN] subset: gosubset_prok synonym: "glycerolphosphorylcholine phosphodiesterase activity" EXACT [EC:3.1.4.2] synonym: "glycerophosphinicocholine diesterase activity" EXACT [EC:3.1.4.2] synonym: "glycerophosphohydrolase activity" EXACT [EC:3.1.4.2] synonym: "glycerylphosphorylcholinediesterase activity" EXACT [EC:3.1.4.2] synonym: "sn-glycero-3-phosphocholine glycerophosphohydrolase activity" EXACT [EC:3.1.4.2] synonym: "sn-glycero-3-phosphorylcholine diesterase activity" EXACT [EC:3.1.4.2] xref: EC:3.1.4.2 xref: GO:0047389 xref: MetaCyc:3.1.4.2-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006698 name: glycerophosphocholine cholinephosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = phosphoryl-choline + glycerol." [EC:3.1.4.38, MetaCyc:3.1.4.38-RXN] synonym: "L-3-glycerylphosphinicocholine cholinephosphohydrolase activity" EXACT [EC:3.1.4.38] synonym: "sn-glycero-3-phosphocholine cholinephosphohydrolase activity" EXACT [EC:3.1.4.38] xref: EC:3.1.4.38 xref: GO:0047390 xref: MetaCyc:3.1.4.38-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006699 name: alkylglycerophosphoethanolamine phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanol-amine + 1-alkyl-sn-glycerol 3-phosphate." [EC:3.1.4.39, MetaCyc:3.1.4.39-RXN] synonym: "1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase activity" EXACT [EC:3.1.4.39] synonym: "lysophospholipase D activity" RELATED [EC:3.1.4.39] xref: EC:3.1.4.39 xref: GO:0047391 xref: MetaCyc:3.1.4.39-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006700 name: CMP-N-acylneuraminate phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP." [EC:3.1.4.40, MetaCyc:3.1.4.40-RXN] synonym: "CMP-N-acetylneuraminate hydrolase activity" EXACT [EC:3.1.4.40] synonym: "CMP-N-acylneuraminate N-acylneuraminohydrolase activity" EXACT [EC:3.1.4.40] synonym: "CMP-N-acylneuraminic acid hydrolase activity" EXACT [EC:3.1.4.40] synonym: "CMP-sialate hydrolase activity" EXACT [EC:3.1.4.40] synonym: "CMP-sialic acid hydrolase activity" EXACT [EC:3.1.4.40] synonym: "cytidine monophosphate-N-acetylneuraminic acid hydrolase activity" EXACT [EC:3.1.4.40] synonym: "cytidine monophosphosialate hydrolase activity" EXACT [EC:3.1.4.40] synonym: "cytidine monophosphosialic hydrolase activity" EXACT [EC:3.1.4.40] xref: EC:3.1.4.40 xref: GO:0047392 xref: MetaCyc:3.1.4.40-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006701 name: glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + glycerol 1,2-cyclic phosphate = glycerol-3-phosphate." [EC:3.1.4.42, MetaCyc:3.1.4.42-RXN] synonym: "rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase activity" EXACT [EC:3.1.4.42] synonym: "rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase activity" EXACT [EC:3.1.4.42] xref: EC:3.1.4.42 xref: GO:0047393 xref: MetaCyc:3.1.4.42-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006702 name: glycerophosphoinositol inositolphosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol." [EC:3.1.4.43, MetaCyc:3.1.4.43-RXN] subset: gosubset_prok synonym: "1,2-cyclic-inositol-phosphate phosphodiesterase activity" EXACT [] synonym: "1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase activity" EXACT [EC:3.1.4.43] synonym: "1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity" EXACT [EC:3.1.4.43] synonym: "D-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity" EXACT [EC:3.1.4.43] synonym: "D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity" EXACT [EC:3.1.4.43] synonym: "D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase activity" EXACT [EC:3.1.4.43] synonym: "inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity" EXACT [EC:3.1.4.43] xref: EC:3.1.4.43 xref: GO:0047394 xref: MetaCyc:3.1.4.43-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006703 name: glycerophosphoinositol glycerophosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + sn-glycero-3-phospho-1-inositol = glycerol-3-phosphate + inositol." [EC:3.1.4.44, MetaCyc:3.1.4.44-RXN] synonym: "1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity" EXACT [EC:3.1.4.44] synonym: "sn-glycero(3)phosphoinositol glycerophosphohydrolase activity" EXACT [EC:3.1.4.44] synonym: "sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity" EXACT [EC:3.1.4.44] xref: EC:3.1.4.44 xref: GO:0047395 xref: MetaCyc:3.1.4.44-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006704 name: glycosylphosphatidylinositol diacylglycerol-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate." [EC:4.6.1.14, MetaCyc:3.1.4.47-RXN] subset: gosubset_prok synonym: "(glycosyl)phosphatidylinositol-specific phospholipase C activity" EXACT [EC:4.6.1.14] synonym: "6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase [6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate-forming]" RELATED [EC:4.6.1.14] synonym: "6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming) activity" EXACT [EC:4.6.1.14] synonym: "glycosyl inositol phospholipid anchor-hydrolyzing enzyme activity" EXACT [EC:4.6.1.14] synonym: "glycosylphosphatidylinositol-phospholipase C activity" NARROW [EC:4.6.1.14] synonym: "glycosylphosphatidylinositol-specific phospholipase C activity" EXACT [EC:4.6.1.14] synonym: "GPI-PLC activity" EXACT [EC:4.6.1.14] synonym: "GPI-specific phospholipase C activity" EXACT [EC:4.6.1.14] synonym: "variant-surface-glycoprotein phospholipase C activity" EXACT [] synonym: "VSG-lipase activity" EXACT [EC:4.6.1.14] xref: EC:4.6.1.14 xref: GO:0047396 xref: MetaCyc:3.1.4.47-RXN is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0006705 name: dolichylphosphate-glucose phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose." [EC:3.1.4.48, MetaCyc:3.1.4.48-RXN] synonym: "Dol-P-Glc phosphodiesterase activity" EXACT [EC:3.1.4.48] synonym: "dolichol phosphoglucose phosphodiesterase activity" EXACT [EC:3.1.4.48] synonym: "dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase activity" EXACT [EC:3.1.4.48] synonym: "dolichyl-phosphate-glucose phosphodiesterase activity" EXACT [] xref: EC:3.1.4.48 xref: GO:0047397 xref: MetaCyc:3.1.4.48-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006706 name: dolichylphosphate-mannose phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose." [EC:3.1.4.49, MetaCyc:3.1.4.49-RXN] synonym: "dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase activity" EXACT [EC:3.1.4.49] synonym: "mannosylphosphodolichol phosphodiesterase activity" EXACT [EC:3.1.4.49] xref: EC:3.1.4.49 xref: GO:0047398 xref: MetaCyc:3.1.4.49-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006707 name: glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate." [EC:3.1.4.51, MetaCyc:3.1.4.51-RXN] synonym: "6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase activity" EXACT [EC:3.1.4.51] synonym: "alpha-glucose-1-phosphate phosphodiesterase activity" EXACT [EC:3.1.4.51] xref: EC:3.1.4.51 xref: GO:0047399 xref: MetaCyc:3.1.4.51-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0006708 name: phosphonoacetate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + phosphonoacetate = phosphate + acetate." [EC:3.11.1.2, MetaCyc:3.11.1.2-RXN] synonym: "phosphonoacetate phosphonohydrolase activity" EXACT [EC:3.11.1.2] xref: EC:3.11.1.2 xref: GO:0047400 xref: MetaCyc:3.11.1.2-RXN is_a: CCO:F0003394 ! hydrolase activity, acting on acid carbon-phosphorus bonds [Term] id: CCO:F0006709 name: trithionate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + trithionate = 2 H+ + SO4(2-) (sulfate) + S2O3(2-)." [EC:3.12.1.1, MetaCyc:3.12.1.1-RXN] synonym: "trithionate thiosulfohydrolase activity" EXACT [EC:3.12.1.1] xref: EC:3.12.1.1 xref: GO:0047401 xref: MetaCyc:3.12.1.1-RXN is_a: CCO:F0003395 ! hydrolase activity, acting on acid sulfur-sulfur bonds [Term] id: CCO:F0006710 name: protein-glucosylgalactosylhydroxylysine glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose." [EC:3.2.1.107, MetaCyc:3.2.1.107-RXN] synonym: "2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity" EXACT [EC:3.2.1.107] synonym: "protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity" EXACT [EC:3.2.1.107] xref: EC:3.2.1.107 xref: GO:0047402 xref: MetaCyc:3.2.1.107-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006711 name: lacto-N-biosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc." [EC:3.2.1.140, MetaCyc:3.2.1.140-RXN] synonym: "oligosaccharide lacto-N-biosylhydrolase activity" RELATED [EC:3.2.1.140] xref: EC:3.2.1.140 xref: GO:0047403 xref: MetaCyc:3.2.1.140-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006712 name: glucuronosyl-disulfoglucosamine glucuronidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2-,6-disulfo-D-glucosamine." [EC:3.2.1.56, MetaCyc:3.2.1.56-RXN] synonym: "3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase activity" EXACT [EC:3.2.1.56] synonym: "3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase activity" EXACT [EC:3.2.1.56] synonym: "glucuronosyl-disulphoglucosamine glucuronidase activity" EXACT [] xref: EC:3.2.1.56 xref: GO:0047404 xref: MetaCyc:3.2.1.56-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006713 name: pyrimidine-5'-nucleotide nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine." [EC:3.2.2.10, MetaCyc:3.2.2.10-RXN] synonym: "Pyr5N activity" EXACT [EC:3.2.2.10] synonym: "pyrimidine nucleotide N-ribosidase activity" EXACT [EC:3.2.2.10] synonym: "pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase activity" EXACT [EC:3.2.2.10] xref: EC:3.2.2.10 xref: GO:0047405 xref: MetaCyc:3.2.2.10-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0006714 name: beta-aspartyl-N-acetylglucosaminidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 1-beta-aspartyl-N-acetyl-D-glucosaminylamine = L-asparagine + N-acetyl-D-glucosamine." [EC:3.2.2.11, MetaCyc:3.2.2.11-RXN] synonym: "1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity" EXACT [EC:3.2.2.11] synonym: "beta-aspartylacetylglucosaminidase activity" EXACT [EC:3.2.2.11] xref: EC:3.2.2.11 xref: GO:0047406 xref: MetaCyc:3.2.2.11-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0006715 name: ADP-ribosyl-[dinitrogen reductase] hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase]." [EC:3.2.2.24, MetaCyc:3.2.2.24-RXN] subset: gosubset_prok synonym: "ADP-D-ribosyl-dinitrogen reductase ADP-ribosylhydrolase activity" EXACT [EC:3.2.2.24] synonym: "ADP-ribosyl glycohydrolase activity" EXACT [EC:3.2.2.24] synonym: "ADP-ribosyl-dinitrogen reductase hydrolase activity" EXACT [EC:3.2.2.24] synonym: "azoferredoxin glycosidase activity" EXACT [EC:3.2.2.24] synonym: "azoferredoxin-activating enzymes" RELATED [EC:3.2.2.24] synonym: "dinitrogenase reductase activating glycohydrolase activity" RELATED [EC:3.2.2.24] synonym: "dinitrogenase reductase-activating glycohydrolase activity" EXACT [EC:3.2.2.24] xref: EC:3.2.2.24 xref: GO:0047407 xref: MetaCyc:3.2.2.24-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0006716 name: alkenylglycerophosphocholine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde." [EC:3.3.2.2, MetaCyc:3.3.2.2-RXN] synonym: "1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase activity" EXACT [EC:3.3.2.2] synonym: "lysoplasmalogenase activity" EXACT [EC:3.3.2.2] xref: EC:3.3.2.2 xref: GO:0047408 xref: MetaCyc:3.3.2.2-RXN is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0006717 name: alkenylglycerophosphoethanolamine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde." [EC:3.3.2.5, MetaCyc:3.3.2.5-RXN] synonym: "1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase activity" EXACT [EC:3.3.2.5] xref: EC:3.3.2.5 xref: GO:0047409 xref: MetaCyc:3.3.2.5-RXN is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0006718 name: N-formylmethionylaminoacyl-tRNA deformylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate." [EC:3.5.1.27, MetaCyc:3.5.1.27-RXN] synonym: "N-formyl-L-methionylaminoacyl-tRNA amidohydrolase activity" EXACT [EC:3.5.1.27] xref: EC:3.5.1.27 xref: GO:0047410 xref: MetaCyc:3.5.1.27-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006719 name: 2-(acetamidomethylene)succinate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate." [EC:3.5.1.29, MetaCyc:3.5.1.29-RXN] synonym: "2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)" EXACT [EC:3.5.1.29] synonym: "alpha-(N-acetylaminomethylene)succinic acid hydrolase activity" EXACT [EC:3.5.1.29] xref: EC:3.5.1.29 xref: GO:0047411 xref: MetaCyc:3.5.1.29-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006720 name: N-(long-chain-acyl)ethanolamine deacylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanol-amine + a fatty acid." [EC:3.5.1.60, MetaCyc:3.5.1.60-RXN] synonym: "acylethanolamine amidase activity" EXACT [] synonym: "N-(long-chain-acyl)ethanolamine amidohydrolase activity" EXACT [] synonym: "N-acylethanolamine amidohydrolase activity" EXACT [] xref: EC:3.5.1.60 xref: GO:0047412 xref: MetaCyc:3.5.1.60-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006721 name: N(alpha)-benzyloxycarbonylleucine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N(alpha)-benzyloxycarbonyl-L-leucine = L-leucine + CO2 + benzyl alcohol." [EC:3.5.1.64, MetaCyc:3.5.1.64-RXN] synonym: "alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase activity" EXACT [EC:3.5.1.64] synonym: "benzyloxycarbonylleucine hydrolase activity" EXACT [EC:3.5.1.64] synonym: "nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV" RELATED [EC:3.5.1.64] synonym: "nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase activity" EXACT [EC:3.5.1.64] synonym: "nalpha-benzyloxycarbonylleucine hydrolase activity" EXACT [EC:3.5.1.64] xref: EC:3.5.1.64 xref: GO:0047413 xref: MetaCyc:3.5.1.64-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006722 name: 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O + 2-(hydroxymethyl)-3-(acetamidomethylene)succinate = CO2 + NH3 + 2-(hydroxymethyl)-4-oxobutanoate + acetate." [EC:3.5.1.66, MetaCyc:3.5.1.66-RXN] synonym: "2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)" EXACT [EC:3.5.1.66] synonym: "alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase activity" EXACT [EC:3.5.1.66] synonym: "compound B hydrolase activity" EXACT [EC:3.5.1.66] xref: EC:3.5.1.66 xref: GO:0047414 xref: MetaCyc:3.5.1.66-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006723 name: D-benzoylarginine-4-nitroanilide amidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-benzoyl-D-arginine-4-nitroanilide = N-benzoyl-D-arginine + 4-nitroaniline." [EC:3.5.1.72, MetaCyc:3.5.1.72-RXN] synonym: "benzoyl-D-arginine arylamidase activity" EXACT [EC:3.5.1.72] synonym: "D-BAPA-ase activity" EXACT [EC:3.5.1.72] synonym: "N-benzoyl-D-arginine-4-nitroanilide amidohydrolase activity" EXACT [EC:3.5.1.72] xref: EC:3.5.1.72 xref: GO:0047415 xref: MetaCyc:3.5.1.72-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006724 name: arylalkyl acylamidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine." [EC:3.5.1.76, MetaCyc:3.5.1.76-RXN] subset: gosubset_prok synonym: "aralkyl acylamidase activity" EXACT [EC:3.5.1.76] synonym: "N-acetylarylalkylamine amidohydrolase activity" EXACT [EC:3.5.1.76] xref: EC:3.5.1.76 xref: GO:0047416 xref: MetaCyc:3.5.1.76-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006725 name: N-carbamoyl-D-amino acid hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid." [EC:3.5.1.77, MetaCyc:3.5.1.77-RXN] subset: gosubset_prok synonym: "N-carbamoyl-D-amino acid amidohydrolase activity" EXACT [EC:3.5.1.77] xref: EC:3.5.1.77 xref: GO:0047417 xref: MetaCyc:3.5.1.77-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006726 name: phthalyl amidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine." [EC:3.5.1.79, MetaCyc:3.5.1.79-RXN] synonym: "o-phthalyl amidase activity" NARROW [EC:3.5.1.79] synonym: "phthalyl-amide amidohydrolase activity" EXACT [EC:3.5.1.79] xref: EC:3.5.1.79 xref: GO:0047418 xref: MetaCyc:3.5.1.79-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006727 name: N-acetylgalactosamine-6-phosphate deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate." [EC:3.5.1.-, MetaCyc:3.5.1.80-RXN] xref: EC:3.5.1.- xref: GO:0047419 xref: MetaCyc:3.5.1.80-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006728 name: N-acyl-D-amino-acid deacylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid." [EC:3.5.1.81, MetaCyc:3.5.1.81-RXN] subset: gosubset_prok synonym: "D-aminoacylase activity" EXACT [EC:3.5.1.81] synonym: "N-acyl-D-amino acid amidohydrolase activity" EXACT [EC:3.5.1.81] xref: EC:3.5.1.81 xref: GO:0047420 xref: MetaCyc:3.5.1.81-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006729 name: N-acyl-D-glutamate deacylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-acyl-D-glutamate = D-glutamate + carboxylate." [EC:3.5.1.82, MetaCyc:3.5.1.82-RXN] subset: gosubset_prok synonym: "N-acyl-D-glutamate amidohydrolase activity" EXACT [EC:3.5.1.82] xref: EC:3.5.1.82 xref: GO:0047421 xref: MetaCyc:3.5.1.82-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006730 name: N-acyl-D-aspartate deacylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-acyl-D-aspartate = D-aspartate + carboxylate." [EC:3.5.1.83, MetaCyc:3.5.1.83-RXN] subset: gosubset_prok synonym: "N-acyl-D-aspartate amidohydrolase activity" EXACT [EC:3.5.1.83] xref: EC:3.5.1.83 xref: GO:0047422 xref: MetaCyc:3.5.1.83-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006731 name: N-methylhydantoinase (ATP-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O + N-methylhydantoin + ATP = phosphate + N-carbamoylsarcosine + ADP." [EC:3.5.2.14, MetaCyc:3.5.2.14-RXN] subset: gosubset_prok synonym: "methylhydantoin amidase activity" EXACT [EC:3.5.2.14] synonym: "N-methylhydantoin amidohydrolase activity" EXACT [EC:3.5.2.14] synonym: "N-methylhydantoin hydrolase activity" EXACT [EC:3.5.2.14] synonym: "N-methylhydantoinase (ATP-hydrolysing)" EXACT [EC:3.5.2.14] synonym: "N-methylhydantoinase activity" EXACT [EC:3.5.2.14] synonym: "N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing)" EXACT [EC:3.5.2.14] xref: EC:3.5.2.14 xref: GO:0047423 xref: MetaCyc:3.5.2.14-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0006732 name: methylenediurea deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O + NH(2)-CO-NH-CH(2)-NH-CO-NH(2) = CO2 + 2 NH3 + N-hydroxymethylurea." [EC:3.5.3.21, MetaCyc:3.5.3.21-RXN] subset: gosubset_prok synonym: "methylenediurea aminohydrolase activity" EXACT [EC:3.5.3.21] synonym: "methylenediurease activity" EXACT [EC:3.5.3.21] xref: EC:3.5.3.21 xref: GO:0047424 xref: MetaCyc:3.5.3.21-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0006733 name: 1-pyrroline-4-hydroxy-2-carboxylate deaminase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + 1-pyrroline-4-hydroxy-2-carboxylate = NH3 + 2,5-dioxopentanoate." [EC:3.5.4.22, MetaCyc:3.5.4.22-RXN] synonym: "1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing)" EXACT [EC:3.5.4.22] synonym: "HPC deaminase activity" EXACT [EC:3.5.4.22] xref: EC:3.5.4.22 xref: GO:0047425 xref: MetaCyc:3.5.4.22-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0006734 name: ricinine nitrilase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone." [EC:3.5.5.2, MetaCyc:3.5.5.2-RXN] synonym: "ricinine aminohydrolase activity" EXACT [EC:3.5.5.2] xref: EC:3.5.5.2 xref: GO:0047426 xref: MetaCyc:3.5.5.2-RXN is_a: CCO:F0000053 ! nitrilase activity [Term] id: CCO:F0006735 name: cyanoalanine nitrilase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O + 3-cyano-L-alanine = NH3 + L-aspartate." [EC:3.5.5.4, MetaCyc:3.5.5.4-RXN] synonym: "3-cyano-L-alanine aminohydrolase activity" EXACT [EC:3.5.5.4] synonym: "beta-cyanoalanine nitrilase activity" EXACT [EC:3.5.5.4] xref: EC:3.5.5.4 xref: GO:0047427 xref: MetaCyc:3.5.5.4-RXN is_a: CCO:F0000053 ! nitrilase activity [Term] id: CCO:F0006736 name: arylacetonitrilase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3." [EC:3.5.5.5, MetaCyc:3.5.5.5-RXN] synonym: "arylacetonitrile aminohydrolase activity" EXACT [EC:3.5.5.5] xref: EC:3.5.5.5 xref: GO:0047428 xref: MetaCyc:3.5.5.5-RXN is_a: CCO:F0000053 ! nitrilase activity [Term] id: CCO:F0006737 name: nucleoside-triphosphate diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a nucleoside triphosphate = pyrophosphate + a nucleotide." [EC:3.6.1.19, MetaCyc:3.6.1.19-RXN] subset: gosubset_prok synonym: "nucleoside-triphosphate diphosphohydrolase activity" EXACT [EC:3.6.1.19] synonym: "nucleoside-triphosphate pyrophosphatase activity" EXACT [] xref: EC:3.6.1.19 xref: GO:0047429 xref: MetaCyc:3.6.1.19-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0006738 name: oligosaccharide-diphosphodolichol diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate." [EC:3.6.1.44, MetaCyc:3.6.1.44-RXN] synonym: "oligosaccharide-diphosphodolichol phosphodolichohydrolase activity" EXACT [EC:3.6.1.44] synonym: "oligosaccharide-diphosphodolichol pyrophosphatase activity" EXACT [] xref: EC:3.6.1.44 xref: GO:0047430 xref: MetaCyc:3.6.1.44-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0006739 name: 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-2-methylpyridine-4,5-dicarboxylate = CO2 + 3-hydroxy-2-methylpyridine-5-carboxylate." [EC:4.1.1.51, MetaCyc:4.1.1.51-RXN] synonym: "3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming)" EXACT [EC:4.1.1.51] synonym: "3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase activity" EXACT [EC:4.1.1.51] xref: EC:4.1.1.51 xref: GO:0047431 xref: MetaCyc:4.1.1.51-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006740 name: 2,2-dialkylglycine decarboxylase (pyruvate) activity namespace: molecular_function def: "Catalysis of the reaction: 2,2-dialkylglycine + pyruvate = dialkyl ketone + L-alanine + CO2." [EC:4.1.1.64, MetaCyc:4.1.1.64-RXN] subset: gosubset_prok synonym: "2,2-dialkyl-2-amino acid-pyruvate aminotransferase activity" EXACT [EC:4.1.1.64] synonym: "2,2-dialkylglycine carboxy-lyase (amino-transferring)" EXACT [EC:4.1.1.64] synonym: "2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)" EXACT [EC:4.1.1.64] synonym: "alpha-dialkyl amino acid transaminase activity" EXACT [EC:4.1.1.64] synonym: "dialkyl amino acid (pyruvate) decarboxylase activity" EXACT [EC:4.1.1.64] synonym: "dialkylamino-acid decarboxylase (pyruvate)" EXACT [EC:4.1.1.64] synonym: "L-alanine-alpha-ketobutyrate aminotransferase activity" EXACT [EC:4.1.1.64] xref: EC:4.1.1.64 xref: GO:0047432 xref: MetaCyc:4.1.1.64-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006741 name: branched-chain-2-oxoacid decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-3-methyl-2-oxopentanoate = 2-methylbutanal + CO2." [EC:4.1.1.72, MetaCyc:4.1.1.72-RXN] synonym: "(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)" EXACT [EC:4.1.1.72] synonym: "(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity" EXACT [EC:4.1.1.72] synonym: "BCKA" RELATED [EC:4.1.1.72] synonym: "branched-chain alpha-keto acid decarboxylase activity" EXACT [EC:4.1.1.72] synonym: "branched-chain keto acid decarboxylase activity" EXACT [EC:4.1.1.72] synonym: "branched-chain oxo acid decarboxylase activity" EXACT [EC:4.1.1.72] xref: EC:4.1.1.72 xref: GO:0047433 xref: MetaCyc:4.1.1.72-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006742 name: indolepyruvate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde." [EC:4.1.1.74, MetaCyc:4.1.1.74-RXN] subset: gosubset_prok synonym: "3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]" RELATED [EC:4.1.1.74] synonym: "3-(indol-3-yl)pyruvate carboxy-lyase activity" EXACT [EC:4.1.1.74] synonym: "indol-3-yl-pyruvate carboxy-lyase activity" EXACT [EC:4.1.1.74] synonym: "indole-3-pyruvate decarboxylase activity" EXACT [EC:4.1.1.74] xref: EC:4.1.1.74 xref: GO:0047434 xref: MetaCyc:4.1.1.74-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006743 name: 5-guanidino-2-oxopentanoate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 5-guanidino-2-oxo-pentanoate = CO2 + 4-guanidinobutanoate." [EC:4.1.1.75, MetaCyc:4.1.1.75-RXN] synonym: "2-oxo-5-guanidinopentanoate carboxy-lyase (4-guanidinobutanal-forming)" EXACT [EC:4.1.1.75] synonym: "2-oxo-5-guanidinopentanoate carboxy-lyase activity" EXACT [EC:4.1.1.75] synonym: "2-oxo-5-guanidinopentanoate decarboxylase activity" EXACT [EC:4.1.1.75] synonym: "2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase activity" EXACT [EC:4.1.1.75] synonym: "alpha-ketoarginine decarboxylase activity" EXACT [EC:4.1.1.75] xref: EC:4.1.1.75 xref: GO:0047435 xref: MetaCyc:4.1.1.75-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006744 name: arylmalonate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-aryl-2-methylmalonate = CO2 + 2-arylpropionate." [EC:4.1.1.76, MetaCyc:4.1.1.76-RXN] subset: gosubset_prok synonym: "2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming)" EXACT [EC:4.1.1.76] synonym: "2-aryl-2-methylmalonate carboxy-lyase activity" EXACT [EC:4.1.1.76] synonym: "AMDASE" RELATED [EC:4.1.1.76] synonym: "AMDase activity" EXACT [EC:4.1.1.76] xref: EC:4.1.1.76 xref: GO:0047436 xref: MetaCyc:4.1.1.76-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006745 name: 4-oxalocrotonate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate." [EC:4.1.1.77, MetaCyc:4.1.1.77-RXN] subset: gosubset_prok synonym: "4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming)" EXACT [EC:4.1.1.77] synonym: "4-oxalocrotonate carboxy-lyase activity" EXACT [EC:4.1.1.77] xref: EC:4.1.1.77 xref: GO:0047437 xref: MetaCyc:4.1.1.77-RXN xref: UM-BBD_enzymeID:e0905 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006746 name: 2-dehydro-3-deoxy-L-pentonate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate." [EC:4.1.2.18, MetaCyc:4.1.2.18-RXN] synonym: "2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.18] synonym: "2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase activity" EXACT [EC:4.1.2.18] synonym: "2-keto-3-deoxy-D-xylonate aldolase activity" EXACT [EC:4.1.2.18] synonym: "2-keto-3-deoxy-L-arabonate aldolase activity" NARROW [EC:4.1.2.18] synonym: "2-keto-3-deoxy-L-pentonate aldolase activity" EXACT [EC:4.1.2.18] synonym: "3-deoxy-D-pentulosonic acid aldolase" BROAD [EC:4.1.2.18] xref: EC:4.1.2.18 xref: GO:0047438 xref: MetaCyc:4.1.2.18-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006747 name: 3-deoxy-D-manno-octulosonate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate." [EC:4.1.2.23, MetaCyc:4.1.2.23-RXN] synonym: "2-keto-3-deoxyoctonate aldolase activity" EXACT [EC:4.1.2.23] synonym: "2-keto-3-deoxyoctonic aldolase activity" EXACT [EC:4.1.2.23] synonym: "3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming)" EXACT [EC:4.1.2.23] synonym: "3-deoxy-D-manno-octulosonate D-arabinose-lyase activity" EXACT [EC:4.1.2.23] synonym: "3-deoxy-D-manno-octulosonic aldolase activity" EXACT [EC:4.1.2.23] synonym: "3-deoxyoctulosonic aldolase activity" EXACT [EC:4.1.2.23] synonym: "KDOaldolase activity" EXACT [EC:4.1.2.23] xref: EC:4.1.2.23 xref: GO:0047439 xref: MetaCyc:4.1.2.23-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006748 name: 2-dehydro-3-deoxy-D-pentonate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-3-deoxy-D-pentonate = glycolaldehyde + pyruvate." [EC:4.1.2.28, MetaCyc:4.1.2.28-RXN] synonym: "2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity" EXACT [EC:4.1.2.28] synonym: "2-keto-3-deoxy-D-pentonate aldolase activity" EXACT [EC:4.1.2.28] synonym: "3-deoxy-D-pentulosonic acid aldolase" BROAD [EC:4.1.2.28] xref: EC:4.1.2.28 xref: GO:0047440 xref: MetaCyc:4.1.2.28-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006749 name: 5-dehydro-2-deoxyphosphogluconate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 5-dehydro-2-deoxy-D-gluconate 6-phosphate = malonate semialdehyde + dihydroxy-acetone-phosphate." [EC:4.1.2.29, MetaCyc:4.1.2.29-RXN] synonym: "5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (pyruvate-forming)" EXACT [EC:4.1.2.29] synonym: "5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase activity" EXACT [EC:4.1.2.29] synonym: "phospho-5-dehydro-2-deoxygluconate aldolase activity" EXACT [EC:4.1.2.29] synonym: "phospho-5-keto-2-deoxygluconate aldolase activity" EXACT [EC:4.1.2.29] xref: EC:4.1.2.29 xref: GO:0047441 xref: MetaCyc:4.1.2.29-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006750 name: 17-alpha-hydroxyprogesterone aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione." [EC:4.1.2.30, MetaCyc:4.1.2.30-RXN] synonym: "17-alpha-hydroxyprogesterone acetaldehyde-lyase activity" EXACT [EC:4.1.2.30] synonym: "17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming)" EXACT [EC:4.1.2.30] synonym: "17alpha-hydroxyprogesterone acetaldehyde-lyase activity" EXACT [EC:4.1.2.30] synonym: "17alpha-hydroxyprogesterone aldolase activity" EXACT [EC:4.1.2.30] synonym: "C-17/C-20 lyase activity" EXACT [EC:4.1.2.30] xref: EC:4.1.2.30 xref: GO:0047442 xref: MetaCyc:4.1.2.30-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006751 name: 4-hydroxy-4-methyl-2-oxoglutarate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate." [EC:4.1.3.17, MetaCyc:4.1.3.17-RXN] subset: gosubset_prok synonym: "4-hydroxy-4-methyl-2-ketoglutarate aldolase activity" EXACT [EC:4.1.3.17] synonym: "4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)" EXACT [EC:4.1.3.17] synonym: "4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase activity" EXACT [EC:4.1.3.17] synonym: "gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase activity" EXACT [EC:4.1.3.17] synonym: "pyruvate aldolase activity" EXACT [EC:4.1.3.17] xref: EC:4.1.3.17 xref: GO:0047443 xref: MetaCyc:4.1.3.17-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0006752 name: N-acylneuraminate-9-phosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate." [EC:2.5.1.57, MetaCyc:4.1.3.20-RXN] synonym: "N-acetylneuraminate 9-phosphate lyase activity" EXACT [EC:2.5.1.57] synonym: "N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity" EXACT [EC:2.5.1.57] synonym: "N-acetylneuraminate 9-phosphate synthetase activity" EXACT [EC:2.5.1.57] synonym: "N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.57] synonym: "phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity" EXACT [EC:2.5.1.57] synonym: "sialic acid 9-phosphate synthetase activity" EXACT [EC:2.5.1.57] xref: EC:2.5.1.57 xref: GO:0047444 xref: MetaCyc:4.1.3.20-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006753 name: 3-hydroxy-3-isohexenylglutaryl-CoA lyase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = acetate + 7-methyl-3-oxooctanoyl-CoA." [EC:4.1.3.26, MetaCyc:4.1.3.26-RXN] synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)" EXACT [EC:4.1.3.26] synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase activity" EXACT [EC:4.1.3.26] synonym: "3-hydroxy-3-isohexenylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.26] synonym: "3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase activity" EXACT [EC:4.1.3.26] synonym: "beta-hydroxy-beta-isohexenylglutaryl CoA-lyase activity" EXACT [EC:4.1.3.26] synonym: "hydroxyisohexenylglutaryl-CoA:acetatelyase activity" EXACT [EC:4.1.3.26] xref: EC:4.1.3.26 xref: GO:0047445 xref: MetaCyc:4.1.3.26-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0006755 name: erythro-3-hydroxyaspartate ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid." [EC:4.3.1.20, MetaCyc:4.3.1.20-RXN] synonym: "3-hydroxyaspartate dehydratase activity" BROAD [EC:4.3.1.20] synonym: "erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.20] synonym: "erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming)" EXACT [EC:4.3.1.20] synonym: "erythro-3-hydroxy-Ls-aspartate ammonia-lyase activity" EXACT [EC:4.3.1.20] synonym: "erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)" EXACT [EC:4.3.1.20] synonym: "erythro-3-hydroxyaspartate dehydratase activity" EXACT [] synonym: "erythro-beta-hydroxyaspartate dehydratase activity" EXACT [EC:4.3.1.20] xref: EC:4.3.1.20 xref: GO:0047447 xref: MetaCyc:4.3.1.20-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0006756 name: 5-dehydro-4-deoxyglucarate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 5-keto-4-deoxy-D-glucarate = CO2 + H2O + 2,5-dioxopentanoate." [EC:4.2.1.41, MetaCyc:4.2.1.41-RXN] subset: gosubset_prok synonym: "5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)" EXACT [EC:4.2.1.41] synonym: "5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)" EXACT [EC:4.2.1.41] synonym: "5-keto-4-deoxy-glucarate dehydratase activity" EXACT [EC:4.2.1.41] synonym: "D-4-deoxy-5-ketoglucarate hydro-lyase activity" EXACT [EC:4.2.1.41] synonym: "deoxyketoglucarate dehydratase activity" EXACT [EC:4.2.1.41] xref: EC:4.2.1.41 xref: GO:0047448 xref: MetaCyc:4.2.1.41-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006757 name: 2-dehydro-3-deoxy-L-arabinonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = H2O + 2,5-dioxopentanoate." [EC:4.2.1.43, MetaCyc:4.2.1.43-RXN] synonym: "2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)" EXACT [EC:4.2.1.43] synonym: "2-dehydro-3-deoxy-L-arabinonate hydro-lyase activity" EXACT [EC:4.2.1.43] synonym: "2-keto-3-deoxy-L-arabinonate dehydratase activity" EXACT [EC:4.2.1.43] xref: EC:4.2.1.43 xref: GO:0047449 xref: MetaCyc:4.2.1.43-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006758 name: crotonoyl-[acyl-carrier-protein] hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein]." [EC:4.2.1.58, MetaCyc:4.2.1.58-RXN] synonym: "(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase activity" EXACT [EC:4.2.1.58] synonym: "(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase (but-2-enoyl-acyl-carrier protein-forming)" EXACT [EC:4.2.1.58] synonym: "(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase activity" EXACT [EC:4.2.1.58] synonym: "3-hydroxybutyryl acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.58] synonym: "beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase activity" EXACT [EC:4.2.1.58] synonym: "beta-hydroxybutyryl acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.58] synonym: "crotonoyl-[acyl-carrier protein] hydratase activity" EXACT [] synonym: "crotonoyl-ACP hydratase activity" EXACT [] synonym: "crotonoyl-acyl-carrier-protein hydratase activity" EXACT [EC:4.2.1.58] synonym: "crotonyl acyl carrier protein hydratase activity" EXACT [EC:4.2.1.58] synonym: "enoyl acyl carrier protein hydrase activity" EXACT [EC:4.2.1.58] xref: EC:4.2.1.58 xref: GO:0047450 xref: MetaCyc:4.2.1.58-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006759 name: 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein]." [EC:4.2.1.59, MetaCyc:4.2.1.59-RXN] synonym: "(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase activity" EXACT [EC:4.2.1.59] synonym: "(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase (oct-2-enoyl-acyl-carrier protein-forming)" EXACT [EC:4.2.1.59] synonym: "(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase activity" EXACT [EC:4.2.1.59] synonym: "3-hydroxyoctanoyl-[acyl-carrier protein] dehydratase activity" EXACT [] synonym: "3-hydroxyoctanoyl-ACP dehydratase activity" EXACT [] synonym: "3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity" EXACT [EC:4.2.1.59] synonym: "beta-hydroxyoctanoyl thioester dehydratase activity" EXACT [EC:4.2.1.59] synonym: "beta-hydroxyoctanoyl-ACP-dehydrase activity" EXACT [EC:4.2.1.59] synonym: "beta-hydroxyoctanoyl-acyl carrier protein dehydrase activity" EXACT [EC:4.2.1.59] synonym: "D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase activity" EXACT [EC:4.2.1.59] synonym: "D-3-hydroxyoctanoyl-acyl carrier protein dehydratase activity" EXACT [EC:4.2.1.59] xref: EC:4.2.1.59 xref: GO:0047451 xref: MetaCyc:4.2.1.59-RXN is_a: CCO:F0004104 ! 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [Term] id: CCO:F0006760 name: protoaphin-aglucone dehydratase (cyclizing) activity namespace: molecular_function def: "Catalysis of the reaction: protoaphin aglucone = H2O + xanthoaphin." [EC:4.2.1.73, MetaCyc:4.2.1.73-RXN] synonym: "protoaphin dehydratase (cyclizing)" EXACT [EC:4.2.1.73] synonym: "protoaphin dehydratase activity" EXACT [EC:4.2.1.73] synonym: "protoaphin-aglucone hydro-lyase (cyclizing)" EXACT [EC:4.2.1.73] synonym: "protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)" EXACT [EC:4.2.1.73] xref: EC:4.2.1.73 xref: GO:0047452 xref: MetaCyc:4.2.1.73-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006761 name: ATP-dependent NAD(P)H-hydrate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide + ATP = phosphate + NADH + ADP." [EC:4.2.1.93, MetaCyc:4.2.1.93-RXN] synonym: "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing)" EXACT [EC:4.2.1.93] synonym: "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ATP-hydrolysing; NADH-forming)" RELATED [EC:4.2.1.93] synonym: "ATP-dependent H(4)NAD(P)OH dehydratase activity" EXACT [] synonym: "ATP-dependent H4NAD(P)OH dehydratase activity" EXACT [] synonym: "reduced nicotinamide adenine dinucleotide hydrate dehydratase activity" EXACT [EC:4.2.1.93] xref: EC:4.2.1.93 xref: GO:0047453 xref: MetaCyc:4.2.1.93-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006762 name: phaseollidin hydratase activity namespace: molecular_function def: "Catalysis of the reaction: phaseollidin hydrate = H2O + phaseollidin." [EC:4.2.1.97, MetaCyc:4.2.1.97-RXN] synonym: "phaseollidin-hydrate hydro-lyase (phaseollidin-forming)" EXACT [EC:4.2.1.97] synonym: "phaseollidin-hydrate hydro-lyase activity" EXACT [EC:4.2.1.97] xref: EC:4.2.1.97 xref: GO:0047454 xref: MetaCyc:4.2.1.97-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006763 name: 16-alpha-hydroxyprogesterone dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone." [EC:4.2.1.98, MetaCyc:4.2.1.98-RXN] synonym: "16-alpha-dehydroxylase activity" EXACT [EC:4.2.1.98] synonym: "16-alpha-hydroxyprogesterone dehydroxylase activity" EXACT [EC:4.2.1.98] synonym: "16-dehydroprogesterone hydratase activity" RELATED [] synonym: "16alpha-dehydroxylase activity" EXACT [EC:4.2.1.98] synonym: "16alpha-hydroxyprogesterone dehydratase activity" EXACT [EC:4.2.1.98] synonym: "16alpha-hydroxyprogesterone dehydroxylase activity" EXACT [EC:4.2.1.98] synonym: "16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)" EXACT [EC:4.2.1.98] synonym: "16alpha-hydroxyprogesterone hydro-lyase activity" EXACT [EC:4.2.1.98] synonym: "hydroxyprogesterone dehydroxylase activity" EXACT [] xref: EC:4.2.1.98 xref: GO:0047455 xref: GO:0047523 xref: MetaCyc:4.2.1.98-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006764 name: 2-methylisocitrate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: methylisocitrate = H2O + 2-methylaconitate." [EC:4.2.1.99, MetaCyc:4.2.1.99-RXN] subset: gosubset_prok synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]" RELATED [EC:4.2.1.99] synonym: "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity" EXACT [EC:4.2.1.99] xref: EC:4.2.1.99 xref: GO:0047456 xref: MetaCyc:4.2.1.99-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006765 name: exo-(1,4)-alpha-D-glucan lyase activity namespace: molecular_function def: "Catalysis of the reaction: linear alpha-glucan = 1,5-anhydro-D-fructose + beta-D-glucose." [EC:4.2.2.13, MetaCyc:4.2.2.13-RXN] synonym: "(1->4)-alpha-D-glucan exo-4-lyase (1,5-anhydro-D-fructose-forming)" EXACT [EC:4.2.2.13] synonym: "alpha-(1->4)-glucan 1,5-anhydro-D-fructose eliminase activity" EXACT [EC:4.2.2.13] synonym: "alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase activity" EXACT [EC:4.2.2.13] synonym: "alpha-1,4-glucan exo-lyase activity" EXACT [EC:4.2.2.13] synonym: "alpha-1,4-glucan lyase activity" BROAD [EC:4.2.2.13] synonym: "exo-(1->4)-alpha-D-glucan lyase activity" EXACT [EC:4.2.2.13] synonym: "exo-alpha-1,4-glucan lyase activity" EXACT [EC:4.2.2.13] xref: EC:4.2.2.13 xref: GO:0047457 xref: MetaCyc:4.2.2.13-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006766 name: beta-pyrazolylalanine synthase activity namespace: molecular_function def: "Catalysis of the reaction: pyrazole + O-acetyl-L-serine = acetate + 3-(pyrazol-1-yl)-L-alanine." [EC:2.5.1.51, MetaCyc:4.2.99.14-RXN] synonym: "3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.51] synonym: "beta-(1-pyrazolyl)alanine synthase activity" EXACT [EC:2.5.1.51] synonym: "beta-pyrazolealanine synthase activity" EXACT [EC:2.5.1.51] synonym: "beta-pyrazolylalanine synthase (acetylserine) activity" EXACT [] synonym: "BPA-synthase activity" EXACT [EC:2.5.1.51] synonym: "O(3)-acetyl-L-serine acetate-lyase (adding pyrazole) activity" EXACT [EC:2.5.1.51] synonym: "O3-acetyl-L-serine acetate-lyase (adding pyrazole)" EXACT [EC:2.5.1.51] synonym: "O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.51] synonym: "pyrazolealanine synthase activity" EXACT [EC:2.5.1.51] synonym: "pyrazolylalaninase activity" EXACT [EC:2.5.1.51] xref: EC:2.5.1.51 xref: GO:0047458 xref: MetaCyc:4.2.99.14-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006767 name: 3-aminobutyryl-CoA ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-3-aminobutyryl-CoA = NH3 + crotonyl-CoA." [EC:4.3.1.14, MetaCyc:4.3.1.14-RXN] synonym: "L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)" EXACT [EC:4.3.1.14] synonym: "L-3-aminobutyryl-CoA ammonia-lyase activity" EXACT [EC:4.3.1.14] synonym: "L-3-aminobutyryl-CoA deaminase activity" EXACT [EC:4.3.1.14] xref: EC:4.3.1.14 xref: GO:0047459 xref: MetaCyc:4.3.1.14-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0006768 name: L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + L-2-amino-4-chloropent-4-enoate = NH3 + HCl + 2-oxopent-4-enoate." [EC:4.5.1.4, MetaCyc:4.5.1.4-RXN] synonym: "L-2-amino-4-chloro-4-pentenoate dehalogenase activity" EXACT [EC:4.5.1.4] synonym: "L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O; deaminating; 2-oxopent-4-enoate-forming)" EXACT [EC:4.5.1.4] synonym: "L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating)" EXACT [EC:4.5.1.4] xref: EC:4.5.1.4 xref: GO:0047460 xref: MetaCyc:4.5.1.4-RXN is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0006770 name: phenylalanine racemase (ATP-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: H2O + L-phenylalanine + ATP = D-phenylalanine + pyrophosphate + AMP." [EC:5.1.1.11, MetaCyc:5.1.1.11-RXN] subset: gosubset_prok synonym: "gramicidin S synthetase I" RELATED [EC:5.1.1.11] synonym: "phenylalanine racemase (adenosine triphosphate-hydrolysing)" EXACT [EC:5.1.1.11] synonym: "phenylalanine racemase (ATP-hydrolysing)" BROAD [EC:5.1.1.11] synonym: "phenylalanine racemase activity" EXACT [EC:5.1.1.11] xref: EC:5.1.1.11 xref: GO:0047462 xref: MetaCyc:5.1.1.11-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0006771 name: 2-aminohexano-6-lactam racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-amino-hexano-6-lactam = D-2-amino-hexano-6-lactam." [EC:5.1.1.15, MetaCyc:5.1.1.15-RXN] synonym: "2-amino-hexano-6-lactam racemase activity" EXACT [EC:5.1.1.15] synonym: "alpha-amino-epsilon-caprolactam racemase activity" EXACT [EC:5.1.1.15] xref: EC:5.1.1.15 xref: GO:0047463 xref: MetaCyc:5.1.1.15-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0006772 name: heparosan-N-sulfate-glucuronate 5-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate." [EC:5.1.3.17, MetaCyc:5.1.3.17-RXN] synonym: "C-5 uronosyl epimerase activity" EXACT [EC:5.1.3.17] synonym: "D-glucuronyl C-5 epimerase activity" EXACT [EC:5.1.3.17] synonym: "heparosan epimerase activity" EXACT [EC:5.1.3.17] synonym: "heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity" EXACT [EC:5.1.3.17] synonym: "heparosan-N-sulphate-glucuronate 5-epimerase activity" EXACT [] synonym: "poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity" EXACT [EC:5.1.3.17] synonym: "polyglucuronate epimerase activity" EXACT [EC:5.1.3.17] xref: EC:5.1.3.17 xref: GO:0047464 xref: MetaCyc:5.1.3.17-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0006773 name: N-acylglucosamine-6-phosphate 2-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate." [EC:5.1.3.9, MetaCyc:5.1.3.9-RXN] subset: gosubset_prok synonym: "acylglucosamine phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] synonym: "acylglucosamine-6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] synonym: "acylmannosamine phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] synonym: "N-acetylglucosmamine 6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] synonym: "N-acetylmannosamine-6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] synonym: "N-acyl-D-glucosamine-6-phosphate 2-epimerase activity" EXACT [EC:5.1.3.9] xref: EC:5.1.3.9 xref: GO:0047465 xref: MetaCyc:5.1.3.9-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0006774 name: 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity namespace: molecular_function def: "Catalysis of the reaction: cis-2-chloro-4-carboxymmethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymmethylenebut-2-en-1,4-olide." [EC:5.2.1.10, MetaCyc:5.2.1.10-RXN] synonym: "2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase activity" EXACT [EC:5.2.1.10] synonym: "2-chlorocarboxymethylenebutenolide isomerase activity" EXACT [EC:5.2.1.-] synonym: "chlorodienelactone isomerase activity" EXACT [EC:5.2.1.-] xref: EC:5.2.1.- xref: EC:5.2.1.10 xref: GO:0018840 xref: GO:0047466 xref: MetaCyc:5.2.1.10-RXN xref: UM-BBD_enzymeID:e0232 is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0006775 name: 4-hydroxyphenylacetaldehyde-oxime isomerase activity namespace: molecular_function def: "Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime." [EC:5.2.1.11, MetaCyc:5.2.1.11-RXN] xref: GO:0047467 xref: MetaCyc:5.2.1.11-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0006776 name: phosphoglucomutase (glucose-cofactor) activity namespace: molecular_function def: "Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor." [EC:5.4.2.5, MetaCyc:5.4.2.5-RXN] synonym: "alpha-D-glucose 1,6-phosphomutase (glucose-cofactor)" EXACT [EC:5.4.2.5] synonym: "glucose-1-phosphate phosphotransferase activity" EXACT [EC:5.4.2.5] xref: EC:5.4.2.5 xref: GO:0047468 xref: MetaCyc:5.4.2.5-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0006777 name: 4-carboxymethyl-4-methylbutenolide mutase activity namespace: molecular_function def: "Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide." [EC:5.4.99.14, MetaCyc:5.4.99.14-RXN] synonym: "4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase activity" EXACT [EC:5.4.99.14] synonym: "4-methyl-2-enelactone isomerase activity" EXACT [EC:5.4.99.14] synonym: "4-methyl-2-enelactone methyl-isomerase activity" EXACT [EC:5.4.99.14] synonym: "4-methyl-3-enelactone methyl isomerase activity" EXACT [EC:5.4.99.14] synonym: "4-methylmuconolactone methylisomerase activity" EXACT [EC:5.4.99.14] xref: EC:5.4.99.14 xref: GO:0047469 xref: MetaCyc:5.4.99.14-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0006779 name: maltose alpha-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: maltose = trehalose." [EC:5.4.99.16, MetaCyc:5.4.99.16-RXN] subset: gosubset_prok synonym: "maltose alpha-D-glucosylmutase activity" EXACT [EC:5.4.99.16] synonym: "maltose glucosylmutase activity" EXACT [EC:5.4.99.16] synonym: "trehalose synthase activity" EXACT [EC:5.4.99.16] xref: EC:5.4.99.16 xref: GO:0047471 xref: MetaCyc:5.4.99.16-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0006780 name: 3-carboxy-cis,cis-muconate cycloisomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate." [EC:5.5.1.2, MetaCyc:5.5.1.2-RXN] subset: gosubset_prok synonym: "2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.2] synonym: "3-carboxymuconate lactonizing enzyme activity" EXACT [EC:5.5.1.2] synonym: "3-carboxymuconolactone hydrolase activity" EXACT [EC:5.5.1.2] synonym: "beta-carboxymuconate lactonizing enzyme activity" EXACT [EC:5.5.1.2] synonym: "CMLE activity" EXACT [EC:5.5.1.2] xref: EC:5.5.1.2 xref: GO:0047472 xref: MetaCyc:5.5.1.2-RXN is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0006781 name: D-alanine-poly(phosphoribitol) ligase activity namespace: molecular_function def: "Catalysis of the reaction: poly(ribitol phosphate) + D-alanine + ATP = O-D-alanyl-poly(ribitol phosphate) + pyrophosphate + AMP." [EC:6.1.1.13, MetaCyc:6.1.1.13-RXN] subset: gosubset_prok synonym: "D-alanine-activating enzyme activity" RELATED [EC:6.1.1.13] synonym: "D-alanine-D-alanyl carrier protein ligase activity" EXACT [EC:6.1.1.13] synonym: "D-alanine-membrane acceptor ligase activity" EXACT [EC:6.1.1.13] synonym: "D-alanine: membrane acceptor ligase activity" EXACT [EC:6.1.1.13] synonym: "D-alanine:poly(phosphoribitol) ligase (AMP-forming)" EXACT [EC:6.1.1.13] synonym: "D-alanyl-poly(phosphoribitol) synthetase activity" EXACT [EC:6.1.1.13] xref: EC:6.1.1.13 xref: GO:0047473 xref: MetaCyc:6.1.1.13-RXN is_a: CCO:F0003435 ! ligase activity, forming aminoacyl-tRNA and related compounds [Term] id: CCO:F0006782 name: long-chain-fatty-acid-luciferin-component ligase activity namespace: molecular_function def: "Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + pyrophosphate + AMP." [EC:6.2.1.19, MetaCyc:6.2.1.19-RXN] subset: gosubset_prok synonym: "acyl-protein synthetase activity" RELATED [EC:6.2.1.19] synonym: "long-chain-fatty-acid:protein ligase (AMP-forming)" EXACT [EC:6.2.1.19] xref: EC:6.2.1.19 xref: GO:0047474 xref: MetaCyc:6.2.1.19-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0006783 name: phenylacetate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: CoA + phenylacetate + ATP = phenylacetyl-CoA + products of ATP breakdown." [EC:6.2.1.30, MetaCyc:6.2.1.21-RXN] subset: gosubset_prok synonym: "PA-CoA ligase activity" EXACT [EC:6.2.1.30] synonym: "phenacyl coenzyme A synthetase activity" EXACT [EC:6.2.1.30] synonym: "phenylacetate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.30] synonym: "phenylacetyl-CoA ligase (AMP-forming)" EXACT [EC:6.2.1.30] synonym: "phenylacetyl-CoA ligase activity" EXACT [EC:6.2.1.30] xref: EC:6.2.1.30 xref: GO:0047475 xref: MetaCyc:PHENYLACETATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0006784 name: 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + pyrophosphate + AMP." [EC:6.2.1.28, MetaCyc:6.2.1.28-RXN] synonym: "3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase activity" EXACT [EC:6.2.1.28] synonym: "3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.28] synonym: "3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.28] synonym: "DHCA-CoA ligase activity" EXACT [EC:6.2.1.28] xref: EC:6.2.1.28 xref: GO:0047476 xref: MetaCyc:6.2.1.28-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0006785 name: aspartate-ammonia ligase (ADP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: NH3 + L-aspartate + ATP = phosphate + L-asparagine + ADP." [EC:6.3.1.4, MetaCyc:6.3.1.4-RXN] synonym: "asparagine synthetase (adenosine diphosphate-forming)" EXACT [EC:6.3.1.4] synonym: "asparagine synthetase (ADP-forming) activity" EXACT [EC:6.3.1.4] synonym: "L-aspartate:ammonia ligase (ADP-forming)" EXACT [EC:6.3.1.4] xref: EC:6.3.1.4 xref: GO:0047478 xref: MetaCyc:6.3.1.4-RXN is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0006786 name: trypanothione synthase activity namespace: molecular_function def: "Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate." [EC:6.3.1.9, MetaCyc:6.3.1.9-RXN] synonym: "glutathionylspermidine:glutathione ligase (ADP-forming)" EXACT [EC:6.3.1.9] synonym: "TSR synthetase activity" EXACT [EC:6.3.1.9] xref: EC:6.3.1.9 xref: GO:0047479 xref: MetaCyc:6.3.1.9-RXN is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0006787 name: UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP." [EC:6.3.2.10, MetaCyc:6.3.2.10-RXN] comment: Note that the enzyme UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase also has UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (GO:0008766). subset: gosubset_prok synonym: "MurF synthetase activity" RELATED [EC:6.3.2.10] synonym: "UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity" EXACT [EC:6.3.2.10] synonym: "UDP-MurNAc-pentapeptide synthetase activity" EXACT [EC:6.3.2.10] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.10] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity" EXACT [EC:6.3.2.10] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity" EXACT [EC:6.3.2.10] synonym: "UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity" EXACT [EC:6.3.2.10] synonym: "UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity" EXACT [] synonym: "UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity" EXACT [EC:6.3.2.10] synonym: "UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity" EXACT [EC:6.3.2.10] synonym: "UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity" EXACT [] synonym: "UDPacetylmuramoylpentapeptide synthetase activity" EXACT [EC:6.3.2.10] synonym: "uridine diphosphoacetylmuramoylpentapeptide synthetase activity" EXACT [EC:6.3.2.10] xref: EC:6.3.2.10 xref: GO:0047480 xref: MetaCyc:6.3.2.10-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0006788 name: D-alanine-alanyl-poly(glycerolphosphate) ligase activity namespace: molecular_function def: "Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP." [EC:6.3.2.16, MetaCyc:6.3.2.16-RXN] synonym: "D-alanine-membrane acceptor-ligase activity" EXACT [EC:6.3.2.16] synonym: "D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)" EXACT [EC:6.3.2.16] synonym: "D-alanine:membrane-acceptor ligase activity" EXACT [EC:6.3.2.16] synonym: "D-alanyl-alanyl-poly(glycerolphosphate) synthetase activity" EXACT [EC:6.3.2.16] synonym: "D-alanyl-poly(phosphoglycerol) synthetase activity" EXACT [EC:6.3.2.16] synonym: "D-alanylalanylpoly(phosphoglycerol) synthetase activity" EXACT [EC:6.3.2.16] xref: EC:6.3.2.16 xref: GO:0047481 xref: MetaCyc:6.3.2.16-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0006789 name: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-lysine + ATP = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ADP." [EC:6.3.2.7, MetaCyc:6.3.2.7-RXN] subset: gosubset_prok synonym: "L-lysine-adding enzyme activity" RELATED [EC:6.3.2.7] synonym: "MurE synthetase activity" RELATED [EC:6.3.2.7] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)" EXACT [EC:6.3.2.7] synonym: "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity" EXACT [EC:6.3.2.7] synonym: "UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity" EXACT [EC:6.3.2.7] synonym: "uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity" EXACT [EC:6.3.2.7] xref: EC:6.3.2.7 xref: GO:0047482 xref: MetaCyc:6.3.2.7-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0006790 name: imidazoleacetate-phosphoribosyldiphosphate ligase activity namespace: molecular_function def: "Catalysis of the reaction: 5-phosphoribosyl diphosphate + imidazole-4-acetate + ATP = phosphate + pyrophosphate + 1-(5-phosphoribosyl)imidazole-4-acetate + ADP." [EC:6.3.4.8, MetaCyc:6.3.4.8-RXN] synonym: "5-phosphoribosylimidazoleacetate synthetase activity" EXACT [EC:6.3.4.8] synonym: "imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming)" EXACT [EC:6.3.4.8] xref: EC:6.3.4.8 xref: GO:0047483 xref: MetaCyc:6.3.4.8-RXN is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0006791 name: protein N-terminus binding namespace: molecular_function def: "Interacting selectively with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "N-terminal binding" EXACT [] xref: GO:0047485 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0006792 name: chondroitin ABC lyase activity namespace: molecular_function def: "Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups." [EC:4.2.2.4] subset: gosubset_prok xref: EC:4.2.2.4 xref: GO:0047486 xref: MetaCyc:4.2.2.4-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006793 name: oligogalacturonide lyase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(4-deoxy-beta-D-gluc-4-enuronosyl)-D-galacturonate = 25-dehydro-4-deoxy-D-glucuronate." [EC:4.2.2.6, MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN] subset: gosubset_prok synonym: "OGTE" RELATED [EC:4.2.2.6] synonym: "oligogalacturonate lyase activity" EXACT [EC:4.2.2.6] synonym: "unsaturated oligogalacturonate transeliminase activity" EXACT [EC:4.2.2.6] xref: EC:4.2.2.6 xref: GO:0047487 xref: MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006794 name: heparin lyase activity namespace: molecular_function def: "Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends." [EC:4.2.2.7, MetaCyc:4.2.2.7-RXN] subset: gosubset_prok synonym: "heparan sulfate lyase activity" RELATED [] synonym: "heparin eliminase activity" RELATED [EC:4.2.2.7] synonym: "heparinase activity" EXACT [EC:4.2.2.7] xref: EC:4.2.2.7 xref: GO:0047488 xref: MetaCyc:4.2.2.7-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006795 name: pectate disaccharide-lyase activity namespace: molecular_function def: "Catalysis of the eliminative cleavage of 4-(4-deoxy-a-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin." [EC:4.2.2.9] subset: gosubset_prok synonym: "(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase activity" EXACT [EC:4.2.2.9] synonym: "exo-PATE" RELATED [EC:4.2.2.9] synonym: "Exo-PATE activity" EXACT [EC:4.2.2.9] synonym: "exo-PGL" RELATED [EC:4.2.2.9] synonym: "Exo-PGL activity" EXACT [EC:4.2.2.9] synonym: "exopectate lyase activity" EXACT [EC:4.2.2.9] synonym: "exopectic acid transeliminase activity" EXACT [EC:4.2.2.9] synonym: "exopolygalacturonate lyase activity" EXACT [EC:4.2.2.9] synonym: "exopolygalacturonic acid-trans-eliminase activity" EXACT [EC:4.2.2.9] synonym: "PATE activity" EXACT [EC:4.2.2.9] synonym: "pectate exo-lyase activity" EXACT [EC:4.2.2.9] xref: EC:4.2.2.9 xref: GO:0047489 xref: MetaCyc:4.2.2.9-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006796 name: pectin lyase activity namespace: molecular_function def: "Catalysis of the eliminative cleavage of (14)-a-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-a-D-galact-4-enuronosyl groups at their nonreducing ends." [EC:4.2.2.10] subset: gosubset_prok synonym: "(1->4)-6-O-methyl-alpha-D-galacturonan lyase activity" EXACT [EC:4.2.2.10] synonym: "endo-pectin lyase activity" EXACT [EC:4.2.2.10] synonym: "pectin methyltranseliminase activity" EXACT [EC:4.2.2.10] synonym: "pectin trans-eliminase activity" BROAD [EC:4.2.2.10] synonym: "pectolyase activity" EXACT [EC:4.2.2.10] synonym: "PL activity" EXACT [EC:4.2.2.10] synonym: "PMGL activity" EXACT [EC:4.2.2.10] synonym: "PNL activity" EXACT [EC:4.2.2.10] synonym: "polymethylgalacturonic transeliminase activity" EXACT [EC:4.2.2.10] xref: EC:4.2.2.10 xref: GO:0047490 xref: MetaCyc:4.2.2.10-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006797 name: poly(alpha-L-guluronate) lyase activity namespace: molecular_function def: "Catalysis of the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends." [EC:4.2.2.11] subset: gosubset_prok synonym: "alginase II activity" RELATED [EC:4.2.2.11] synonym: "guluronate lyase activity" EXACT [EC:4.2.2.11] synonym: "L-guluronan lyase activity" EXACT [EC:4.2.2.11] synonym: "L-guluronate lyase activity" EXACT [EC:4.2.2.11] synonym: "poly(alpha-L-1,4-guluronide) exo-lyase activity" EXACT [EC:4.2.2.11] synonym: "poly-alpha-L-guluronate lyase activity" EXACT [EC:4.2.2.11] synonym: "polyguluronate-specific alginate lyase activity" EXACT [EC:4.2.2.11] xref: EC:4.2.2.11 xref: GO:0047491 xref: MetaCyc:4.2.2.11-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006798 name: xanthan lyase activity namespace: molecular_function def: "Catalysis of the eliminative cleavage of the terminal b-D-mannosyl-b-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-a-L-threo-hex-4-enuronosyl group at the terminus of the side-chain." [EC:4.2.2.12] xref: EC:4.2.2.12 xref: GO:0047492 xref: MetaCyc:4.2.2.12-RXN is_a: CCO:F0003403 ! carbon-oxygen lyase activity, acting on polysaccharides [Term] id: CCO:F0006799 name: ceramide cholinephosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-choline + N-acylsphingosine = CMP + sphingomyelin." [EC:2.7.8.3] subset: gosubset_prok synonym: "CDP-choline:N-acylsphingosine cholinephosphotransferase activity" EXACT [EC:2.7.8.3] synonym: "phosphorylcholine-ceramide transferase activity" EXACT [EC:2.7.8.3] xref: EC:2.7.8.3 xref: GO:0047493 xref: MetaCyc:CERAMIDE-CHOLINEPHOSPHOTRANSFERASE-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006800 name: serine-phosphoethanolamine synthase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-ethanolamine + L-serine = CMP + L-serine-phosphoethanolamine." [EC:2.7.8.4] synonym: "CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity" EXACT [EC:2.7.8.4] synonym: "serine ethanolamine phosphate synthetase activity" EXACT [EC:2.7.8.4] synonym: "serine ethanolamine phosphodiester synthase activity" EXACT [EC:2.7.8.4] synonym: "serine ethanolaminephosphotransferase activity" EXACT [EC:2.7.8.4] synonym: "serine-phosphinico-ethanolamine synthase activity" EXACT [EC:2.7.8.4] synonym: "serinephosphoethanolamine synthase activity" EXACT [EC:2.7.8.4] xref: EC:2.7.8.4 xref: GO:0047494 xref: MetaCyc:SERINE-PHOSPHOETHANOLAMINE-SYNTHASE-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006801 name: membrane-oligosaccharide glycerophosphotransferase activity namespace: molecular_function def: "Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another." [EC:2.7.8.21] synonym: "membrane-derived-oligosaccharide-6-(glycerophospho)-D-glucose:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity" EXACT [EC:2.7.8.21] synonym: "periplasmic phosphoglycerotransferase activity" NARROW [EC:2.7.8.21] synonym: "phosphoglycerol cyclase activity" RELATED [EC:2.7.8.21] xref: EC:2.7.8.21 xref: GO:0047495 xref: MetaCyc:2.7.8.21-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0006802 name: calcium-dependent phospholipase A2 activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate; requires Ca2+." [EC:3.1.1.4] synonym: "calcium-dependent cytosolic phospholipase A2 activity" NARROW [] synonym: "calcium-dependent secreted phospholipase A2 activity" NARROW [] xref: GO:0047498 is_a: CCO:F0001002 ! phospholipase A2 activity [Term] id: CCO:F0006803 name: calcium-independent phospholipase A2 activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate; does not require Ca2+." [EC:3.1.1.4] synonym: "calcium-independent cytosolic phospholipase A2 activity" NARROW [] xref: GO:0047499 is_a: CCO:F0001002 ! phospholipase A2 activity [Term] id: CCO:F0006817 name: 1,2-alpha-L-fucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside." [EC:3.2.1.63, MetaCyc:1] synonym: "2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase activity" EXACT [EC:3.2.1.63] synonym: "almond emulsin fucosidase activity" EXACT [EC:3.2.1.63] synonym: "almond emulsin fucosidase II activity" NARROW [EC:3.2.1.63] synonym: "alpha-(1->2)-L-fucosidase activity" EXACT [EC:3.2.1.63] xref: EC:3.2.1.63 xref: GO:0047513 xref: MetaCyc:1 is_a: CCO:F0000945 ! alpha-L-fucosidase activity [Term] id: CCO:F0006818 name: 1,3-beta-D-glucan phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin." [EC:2.4.1.97, MetaCyc:1] synonym: "1,3-beta-D-glucan:orthophosphate glucosyltransferase activity" EXACT [EC:2.4.1.97] synonym: "1,3-beta-D-glucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.97] synonym: "1,3-beta-glucan phosphorylase activity" EXACT [] synonym: "laminarin phosphorylase activity" RELATED [EC:2.4.1.97] synonym: "laminarin phosphoryltransferase activity" EXACT [EC:2.4.1.97] xref: EC:2.4.1.97 xref: GO:0047514 xref: MetaCyc:1 is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0006819 name: 1,3-beta-oligoglucan phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: oligomeric 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate." [EC:2.4.1.30, MetaCyc:1] synonym: "1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.30] synonym: "beta-1,3-oligoglucan phosphorylase activity" EXACT [EC:2.4.1.30] synonym: "beta-1,3-oligoglucan:orthophosphate glucosyltransferase II activity" EXACT [EC:2.4.1.30] xref: EC:2.4.1.30 xref: GO:0047515 xref: MetaCyc:1 is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0006820 name: 1,3-propanediol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+." [EC:1.1.1.202, MetaCyc:1] subset: gosubset_prok synonym: "1,3-PD:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.202] synonym: "1,3-propanediol oxidoreductase activity" EXACT [EC:1.1.1.202] synonym: "1,3-propanediol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.202] synonym: "3-hydroxypropionaldehyde reductase activity" EXACT [EC:1.1.1.202] synonym: "propane-1,3-diol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.202] xref: EC:1.1.1.202 xref: GO:0047516 xref: MetaCyc:1 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006821 name: 1,4-beta-D-xylan synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-D-xylose + 1,4-beta-D-xylan(n) = UDP + 1,4-beta-D-xylan(n+1)." [EC:2.4.2.24, MetaCyc:1] synonym: "1,4-beta-xylan synthase activity" EXACT [EC:2.4.2.24] synonym: "UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.24] synonym: "uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase activity" EXACT [EC:2.4.2.24] synonym: "xylan synthase activity" EXACT [EC:2.4.2.24] synonym: "xylan synthetase activity" EXACT [EC:2.4.2.24] xref: EC:2.4.2.24 xref: GO:0047517 xref: MetaCyc:1 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0006822 name: 1-methyladenosine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: 1-methyladenosine + H2O = 1-methyladenine + D-ribose." [EC:3.2.2.13, MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN] synonym: "1-methyladenosine hydrolase activity" EXACT [EC:3.2.2.13] synonym: "1-methyladenosine ribohydrolase activity" EXACT [EC:3.2.2.13] xref: EC:3.2.2.13 xref: GO:0047518 xref: MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0006823 name: quinate dehydrogenase (pyrroloquinoline-quinone) activity namespace: molecular_function def: "Catalysis of the reaction: quinate + pyrroloquinoline-quinone = 5-dehydroquinate + reduced pyrroloquinoline-quinone." [EC:1.1.99.25, MetaCyc:1.1.99.25-RXN] subset: gosubset_prok synonym: "NAD(P)-independent quinate dehydrogenase activity" EXACT [EC:1.1.99.25] synonym: "quinate:pyrroloquinoline-quinone 3-oxidoreductase activity" EXACT [EC:1.1.99.25] synonym: "quinate:pyrroloquinoline-quinone 5-oxidoreductase activity" EXACT [EC:1.1.99.25] xref: EC:1.1.99.25 xref: GO:0047519 xref: MetaCyc:1.1.99.25-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0006824 name: 11-cis-retinyl-palmitate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate." [EC:3.1.1.63, MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN] synonym: "11-cis-retinol palmitate esterase activity" EXACT [EC:3.1.1.63] synonym: "11-cis-retinyl-palmitate acylhydrolase activity" EXACT [EC:3.1.1.63] synonym: "RPH" RELATED [EC:3.1.1.63] xref: EC:3.1.1.63 xref: GO:0047520 xref: MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006825 name: 12-beta-hydroxysteroid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-alpha,7-alpha,12-beta-trihydroxy-5-beta-cholanate + NADP+ = 3-alpha,7-alpha-dihydroxy-12-oxo-5-beta-cholanate + NADPH + H+." [EC:1.1.1.238, MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN] synonym: "12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.238] synonym: "12beta-hydroxysteroid dehydrogenase activity" EXACT [EC:1.1.1.238] synonym: "12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity" EXACT [EC:1.1.1.238] xref: EC:1.1.1.238 xref: GO:0047521 xref: MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006826 name: 15-oxoprostaglandin 13-oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+." [EC:1.3.1.48, MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN] synonym: "(5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity" EXACT [EC:1.3.1.48] synonym: "15-ketoprostaglandin delta13-reductase activity" EXACT [EC:1.3.1.48] synonym: "15-oxo-delta13-prostaglandin reductase activity" EXACT [EC:1.3.1.48] synonym: "15-oxoprostaglandin 13-reductase activity" EXACT [] synonym: "delta13-15-ketoprostaglandin reductase activity" EXACT [EC:1.3.1.48] synonym: "prostaglandin 13-reductase activity" EXACT [EC:1.3.1.48] synonym: "prostaglandin delta13-reductase activity" EXACT [EC:1.3.1.48] xref: EC:1.3.1.48 xref: GO:0047522 xref: MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006827 name: 16-hydroxysteroid epimerase activity namespace: molecular_function def: "Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid." [EC:5.1.99.2, MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN] synonym: "16-hydroxysteroid 16-epimerase activity" EXACT [EC:5.1.99.2] xref: EC:5.1.99.2 xref: GO:0047524 xref: MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN is_a: CCO:F0003417 ! racemase and epimerase activity [Term] id: CCO:F0006828 name: 2'-hydroxydaidzein reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzen + NADPH + H+." [EC:1.3.1.51, MetaCyc:2] synonym: "2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.3.1.51] synonym: "2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase activity" EXACT [EC:1.3.1.51] synonym: "2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.3.1.51] synonym: "HDR activity" EXACT [EC:1.3.1.51] synonym: "NADPH:2'-hydroxydaidzein oxidoreductase activity" EXACT [EC:1.3.1.51] xref: EC:1.3.1.51 xref: GO:0047525 xref: MetaCyc:2 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006829 name: 2'-hydroxyisoflavone reductase activity namespace: molecular_function def: "Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+." [EC:1.3.1.45, MetaCyc:2] subset: gosubset_prok synonym: "2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase activity" EXACT [EC:1.3.1.45] synonym: "isoflavone reductase activity" EXACT [EC:1.3.1.45] synonym: "NADPH:2'-hydroxyisoflavone oxidoreductase activity" EXACT [EC:1.3.1.45] synonym: "vestitone:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.45] xref: EC:1.3.1.45 xref: GO:0047526 xref: MetaCyc:2 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006830 name: 2,3-dihydroxybenzoate-serine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine." [EC:6.3.2.14, MetaCyc:1] synonym: "2,3-dihydroxybenzoate:L-serine ligase activity" EXACT [EC:6.3.2.14] synonym: "2,3-dihydroxybenzoylserine synthetase activity" EXACT [EC:6.3.2.14] synonym: "N-(2,3-dihydroxybenzoyl)-serine synthetase activity" EXACT [EC:6.3.2.14] xref: EC:6.3.2.14 xref: GO:0047527 xref: MetaCyc:2 is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0006831 name: 2,3-dihydroxyindole 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxyindole + O2 = anthranilate + CO2." [EC:1.13.11.23, MetaCyc:2] synonym: "2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing) activity" EXACT [EC:1.13.11.23] xref: EC:1.13.11.23 xref: GO:0047528 xref: MetaCyc:2 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006832 name: 2,3-dimethylmalate lyase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dimethylmalate = propanoate + pyruvate." [EC:4.1.3.32, MetaCyc:2] synonym: "(2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)" EXACT [EC:4.1.3.32] synonym: "(2R,3S)-2,3-dimethylmalate pyruvate-lyase activity" EXACT [EC:4.1.3.32] synonym: "2,3-dimethylmalate pyruvate-lyase activity" EXACT [EC:4.1.3.32] xref: EC:4.1.3.32 xref: GO:0047529 xref: MetaCyc:2 is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0006833 name: 2,4-diaminopentanoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+." [EC:1.4.1.12, MetaCyc:2] synonym: "2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.12] synonym: "2,4-diaminopentanoic acid C4 dehydrogenase activity" EXACT [EC:1.4.1.12] xref: EC:1.4.1.12 xref: GO:0047530 xref: MetaCyc:2 is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006834 name: 2,5-diaminovalerate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-diaminopentanoate + 2-oxoglutarate = 5-amino-2-oxopentanoate + L-glutamate." [EC:2.6.1.8, MetaCyc:2] synonym: "2,5-diaminopentanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.8] synonym: "2,5-diaminovalerate aminotransferase activity" EXACT [] synonym: "diamino acid aminotransferase activity" EXACT [EC:2.6.1.8] synonym: "diamino-acid aminotransferase activity" RELATED [EC:2.6.1.8] synonym: "diamino-acid transaminase activity" EXACT [EC:2.6.1.8] xref: EC:2.6.1.8 xref: GO:0047531 xref: MetaCyc:2 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006835 name: 2,5-dioxopiperazine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-dioxopiperazine + H2O = glycylglycine." [EC:3.5.2.13, MetaCyc:2] synonym: "2,5-dioxopiperazine amidohydrolase activity" EXACT [EC:3.5.2.13] synonym: "cyclo(Gly-Gly) hydrolase activity" EXACT [EC:3.5.2.13] synonym: "cyclo(glycylglycine) hydrolase activity" EXACT [EC:3.5.2.13] xref: EC:3.5.2.13 xref: GO:0047532 xref: MetaCyc:2 is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0006836 name: 2,5-dioxovalerate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+." [EC:1.2.1.26, MetaCyc:2] synonym: "2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity" EXACT [EC:1.2.1.26] synonym: "2-oxoglutarate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.26] synonym: "alpha-ketoglutaric semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.26] xref: EC:1.2.1.26 xref: GO:0047533 xref: MetaCyc:2 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006837 name: 2-acetolactate mutase activity namespace: molecular_function def: "Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate." [EC:5.4.99.3, MetaCyc:2-ACETOLACTATE-MUTASE-RXN] synonym: "2-acetolactate methylmutase activity" EXACT [EC:5.4.99.3] synonym: "acetohydroxy acid isomerase activity" BROAD [EC:5.4.99.3] synonym: "acetolactate mutase activity" EXACT [EC:5.4.99.3] xref: EC:5.4.99.3 xref: GO:0047534 xref: MetaCyc:2-ACETOLACTATE-MUTASE-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0006838 name: 2-alkyn-1-ol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-butyne-1,4-diol + NAD+ = 4-hydroxy-2-butynal + NADH + H+." [EC:1.1.1.165, MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN] synonym: "2-butyne-1,4-diol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.165] xref: EC:1.1.1.165 xref: GO:0047535 xref: MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006839 name: 2-aminoadipate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate." [EC:2.6.1.39, MetaCyc:2-AMINOADIPATE-AMINOTRANSFERASE-RXN] synonym: "2-aminoadipate aminotransferase activity" EXACT [] synonym: "2-aminoadipic aminotransferase activity" EXACT [EC:2.6.1.39] synonym: "alpha-aminoadipate aminotransferase activity" EXACT [EC:2.6.1.39] synonym: "glutamate-alpha-ketoadipate transaminase activity" EXACT [EC:2.6.1.39] synonym: "glutamic-ketoadipic transaminase activity" EXACT [EC:2.6.1.39] synonym: "L-2-aminoadipate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.39] xref: EC:2.6.1.39 xref: GO:0047536 xref: MetaCyc:2-AMINOADIPATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006840 name: 2-aminohexanoate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate." [EC:2.6.1.67, MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN] synonym: "2-aminohexanoate aminotransferase activity" EXACT [] synonym: "L-2-aminohexanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.67] synonym: "leucine L-norleucine: 2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.67] synonym: "norleucine (leucine) aminotransferase activity" EXACT [EC:2.6.1.67] synonym: "norleucine aminotransferase activity" EXACT [EC:2.6.1.67] synonym: "norleucine transaminase activity" EXACT [EC:2.6.1.67] xref: EC:2.6.1.67 xref: GO:0047537 xref: MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006841 name: 2-carboxy-D-arabinitol-1-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H2O = 2-carboxy-D-arabinitol + phosphate." [EC:3.1.3.63, MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN] synonym: "2-carboxy-D-arabinitol 1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.63] synonym: "2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.63] synonym: "2-carboxyarabinitol 1-phosphatase activity" EXACT [EC:3.1.3.63] xref: EC:3.1.3.63 xref: GO:0047538 xref: MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006842 name: 2-deoxyglucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol." [EC:3.2.1.112, MetaCyc:2-DEOXYGLUCOSIDASE-RXN] synonym: "2-deoxy-alpha-D-glucosidase activity" EXACT [EC:3.2.1.112] synonym: "2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity" EXACT [EC:3.2.1.112] synonym: "2-deoxy-alpha-glucosidase activity" EXACT [EC:3.2.1.112] xref: EC:3.2.1.112 xref: GO:0047539 xref: MetaCyc:2-DEOXYGLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006843 name: 2-enoate reductase activity namespace: molecular_function def: "Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+." [EC:1.3.1.31, MetaCyc:2-ENOATE-REDUCTASE-RXN] subset: gosubset_prok synonym: "butanoate:NAD+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.31] synonym: "enoate reductase activity" EXACT [EC:1.3.1.31] xref: EC:1.3.1.31 xref: GO:0047540 xref: MetaCyc:2-ENOATE-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006844 name: 2-furoate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-furoate + CoA = AMP + diphosphate + 2-furoyl-CoA." [EC:6.2.1.31, MetaCyc:2-FUROATE--COA-LIGASE-RXN] synonym: "2-furoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.31] synonym: "2-furoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.31] xref: EC:6.2.1.31 xref: GO:0047541 xref: MetaCyc:2-FUROATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0006845 name: 2-furoyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-furoyl-CoA + H2O + acceptor = S-(5-hydroxy-2-furoyl)-CoA + reduced acceptor." [EC:1.3.99.8, MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN] synonym: "2-furoyl coenzyme A dehydrogenase activity" EXACT [EC:1.3.99.8] synonym: "2-furoyl coenzyme A hydroxylase activity" EXACT [EC:1.3.99.8] synonym: "2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.8] synonym: "2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)" EXACT [EC:1.3.99.8] synonym: "furoyl-CoA hydroxylase activity" EXACT [EC:1.3.99.8] xref: EC:1.3.99.8 xref: GO:0047542 xref: MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0006846 name: 2-hexadecenal reductase activity namespace: molecular_function def: "Catalysis of the reaction: hexadecanal + NADP+ = 2-trans-hexadecenal + NADPH + H+." [EC:1.3.1.27, MetaCyc:2-HEXADECENAL-REDUCTASE-RXN] synonym: "hexadecanal: NADP+ oxidoreductase activity" EXACT [EC:1.3.1.27] synonym: "hexadecanal:NADP+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.27] xref: EC:1.3.1.27 xref: GO:0047543 xref: MetaCyc:2-HEXADECENAL-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006847 name: 2-hydroxybiphenyl 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxybiphenyl + NADH + H+ + O2 = 2,3-dihydroxybiphenyl + NAD+ + H2O." [EC:1.14.13.44, MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN] synonym: "2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.44] xref: EC:1.14.13.44 xref: GO:0047544 xref: MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0896 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006848 name: 2-hydroxyglutarate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor." [EC:1.1.99.2, MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase" EXACT [EC:1.1.99.2] synonym: "(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase" EXACT [EC:1.1.99.2] synonym: "alpha-hydroxyglutarate dehydrogenase (NAD+ specific)" NARROW [EC:1.1.99.2] synonym: "alpha-hydroxyglutarate dehydrogenase activity" EXACT [EC:1.1.99.2] synonym: "alpha-hydroxyglutarate oxidoreductase activity" EXACT [EC:1.1.99.2] synonym: "alpha-ketoglutarate reductase activity" EXACT [EC:1.1.99.2] synonym: "hydroxyglutaric dehydrogenase activity" EXACT [EC:1.1.99.2] synonym: "L-alpha-hydroxyglutarate dehydrogenase activity" EXACT [EC:1.1.99.2] synonym: "L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase" NARROW [EC:1.1.99.2] xref: EC:1.1.99.2 xref: GO:0047545 xref: MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0006849 name: 2-hydroxypyridine 5-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxypyridine + donor-H2 + O2 = 2,5-dihydroxypyridine + acceptor + H2O." [EC:1.14.99.26, MetaCyc:2-HYDROXYPYRIDINE-5-MONOOXYGENASE-RXN] synonym: "2-hydroxypyridine oxygenase activity" EXACT [EC:1.14.99.26] synonym: "2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.99.26] xref: EC:1.14.99.26 xref: GO:0047546 xref: MetaCyc:2-HYDROXYPYRIDINE-5-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0006850 name: 2-methylcitrate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O." [EC:4.2.1.79, MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN] subset: gosubset_prok synonym: "(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]" RELATED [EC:4.2.1.79] synonym: "2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity" EXACT [EC:4.2.1.79] synonym: "2-methylcitrate hydro-lyase activity" EXACT [EC:4.2.1.79] synonym: "prpD" RELATED [EC:4.2.1.79] xref: EC:4.2.1.79 xref: GO:0047547 xref: MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006851 name: 2-methyleneglutarate mutase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate." [EC:5.4.99.4, MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN] subset: gosubset_prok synonym: "2-methyleneglutarate carboxy-methylenemethylmutase activity" EXACT [EC:5.4.99.4] synonym: "alpha-methyleneglutarate mutase activity" EXACT [EC:5.4.99.4] xref: EC:5.4.99.4 xref: GO:0047548 xref: MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0006852 name: 2-nitrophenol 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-nitrophenol + NADPH + H+ + O2 = catechol + NO2(-) (nitrite) + NADP+ + H2O." [EC:1.14.13.31, MetaCyc:2-NITROPHENOL-2-MONOOXYGENASE-RXN] synonym: "2-nitrophenol oxygenase activity" EXACT [EC:1.14.13.31] synonym: "2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)" EXACT [EC:1.14.13.31] synonym: "nitrophenol oxygenase activity" BROAD [EC:1.14.13.31] xref: EC:1.14.13.31 xref: GO:0047549 xref: MetaCyc:2-NITROPHENOL-2-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0951 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006853 name: 2-oxoadipate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxyadipate + NAD+ = 2-oxoadipate + NADH + H+." [EC:1.1.1.172, MetaCyc:2-OXOADIPATE-REDUCTASE-RXN] synonym: "2-hydroxyadipate:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.172] synonym: "2-ketoadipate reductase activity" EXACT [EC:1.1.1.172] synonym: "alpha-ketoadipate reductase activity" EXACT [EC:1.1.1.172] xref: EC:1.1.1.172 xref: GO:0047550 xref: MetaCyc:2-OXOADIPATE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006854 name: 2-oxoaldehyde dehydrogenase (NAD) activity namespace: molecular_function def: "Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+." [EC:1.2.1.23, MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-(NAD+)-RXN] synonym: "2-ketoaldehyde dehydrogenase" BROAD [EC:1.2.1.23] synonym: "2-oxoaldehyde dehydrogenase (NAD+)" EXACT [EC:1.2.1.23] synonym: "2-oxoaldehyde:NAD+ 2-oxidoreductase activity" EXACT [EC:1.2.1.23] synonym: "alpha-ketoaldehyde dehydrogenase activity" BROAD [EC:1.2.1.23] synonym: "methylglyoxal dehydrogenase activity" BROAD [EC:1.2.1.23] synonym: "NAD-dependent alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.23] synonym: "NAD-linked alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.23] xref: EC:1.2.1.23 xref: GO:0047551 xref: MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-(NAD+)-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006855 name: 2-oxoaldehyde dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+." [EC:1.2.1.49, MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-(NADP+)-RXN] synonym: "2-ketoaldehyde dehydrogenase" BROAD [EC:1.2.1.49] synonym: "2-oxoaldehyde:NADP+ 2-oxidoreductase activity" EXACT [EC:1.2.1.49] synonym: "alpha-ketoaldehyde dehydrogenase activity" BROAD [EC:1.2.1.49] synonym: "methylglyoxal dehydrogenase activity" BROAD [EC:1.2.1.49] synonym: "NADP-dependent alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.49] synonym: "NADP-linked alpha-ketoaldehyde dehydrogenase activity" EXACT [EC:1.2.1.49] xref: EC:1.2.1.49 xref: GO:0047552 xref: MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006856 name: 2-oxoglutarate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin." [EC:1.2.7.3, MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN] subset: gosubset_prok synonym: "2-ketoglutarate ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] synonym: "2-oxoglutarate ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] synonym: "2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating)" EXACT [EC:1.2.7.3] synonym: "2-oxoglutarate:ferredoxin 2-oxidoreductase (decarboxylating)" EXACT [EC:1.2.7.3] synonym: "2-oxoglutarate:ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] synonym: "alpha-ketoglutarate synthase activity" EXACT [EC:1.2.7.3] synonym: "alpha-ketoglutarate-ferredoxin oxidoreductase activity" EXACT [EC:1.2.7.3] synonym: "KGOR activity" EXACT [EC:1.2.7.3] xref: EC:1.2.7.3 xref: GO:0047553 xref: MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN is_a: CCO:F0003227 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0006857 name: 2-pyrone-4,6-dicarboxylate lactonase activity namespace: molecular_function def: "Catalysis of the reaction: 2-pyrone-4,6-dicarboxylate + H2O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate." [EC:3.1.1.57, MetaCyc:2-PYRONE-4] subset: gosubset_prok synonym: "2-pyrone-4,6-dicarboxylate lactonohydrolase activity" EXACT [EC:3.1.1.57] xref: EC:3.1.1.57 xref: GO:0047554 xref: MetaCyc:2-PYRONE-4 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006858 name: 3',5'-cyclic-GMP phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate." [EC:3.1.4.35, MetaCyc:3] synonym: "3',5' cyclic-GMP phosphodiesterase activity" EXACT [] synonym: "3',5'-cyclic-GMP 5'-nucleotidohydrolase activity" EXACT [EC:3.1.4.35] synonym: "cGMP phosphodiesterase activity" EXACT [] synonym: "cGMP-PDE" RELATED [EC:3.1.4.35] synonym: "cGMP-specific phosphodiesterase activity" EXACT [] synonym: "cyclic 3',5'-GMP phosphodiesterase activity" EXACT [EC:3.1.4.35] synonym: "cyclic GMP phosphodiesterase activity" EXACT [] synonym: "cyclic guanosine 3',5'-monophosphate phosphodiesterase activity" EXACT [EC:3.1.4.35] synonym: "cyclic guanosine 3',5'-phosphate phosphodiesterase activity" EXACT [EC:3.1.4.35] synonym: "guanosine cyclic 3',5'-phosphate phosphodiesterase activity" EXACT [] xref: EC:3.1.4.35 xref: GO:0004116 xref: GO:0047555 xref: MetaCyc:3 is_a: CCO:F0000586 ! 3',5'-cyclic-nucleotide phosphodiesterase activity [Term] id: CCO:F0006859 name: 3,4-dihydroxyphthalate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2." [EC:4.1.1.69] synonym: "3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)" EXACT [EC:4.1.1.69] synonym: "3,4-dihydroxyphthalate carboxy-lyase activity" EXACT [EC:4.1.1.69] xref: EC:4.1.1.69 xref: GO:0047556 xref: MetaCyc:3 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006860 name: 3-aci-nitropropanoate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + O2 + 3-aci-nitropropanoate = NO2(-) (nitrite) + H2O2 + 3-oxopropanoate." [EC:1.7.3.5, MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN] synonym: "3-aci-nitropropanoate:oxygen oxidoreductase activity" EXACT [EC:1.7.3.5] synonym: "propionate-3-nitronate oxidase activity" EXACT [EC:1.7.3.5] xref: EC:1.7.3.5 xref: GO:0047557 xref: MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN is_a: CCO:F0003258 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor [Term] id: CCO:F0006861 name: 3-cyanoalanine hydratase activity namespace: molecular_function def: "Catalysis of the reaction: L-asparagine = 3-cyanoalanine + H2O." [EC:4.2.1.65, MetaCyc:3-CYANOALANINE-HYDRATASE-RXN] synonym: "beta-CNA nitrilase activity" EXACT [EC:4.2.1.65] synonym: "beta-CNAla hydrolase activity" EXACT [EC:4.2.1.65] synonym: "beta-cyanoalanine hydratase activity" EXACT [EC:4.2.1.65] synonym: "beta-cyanoalanine hydrolase activity" EXACT [EC:4.2.1.65] synonym: "L-asparagine hydro-lyase (3-cyanoalanine-forming)" EXACT [EC:4.2.1.65] synonym: "L-asparagine hydro-lyase activity" EXACT [EC:4.2.1.65] xref: EC:4.2.1.65 xref: GO:0047558 xref: MetaCyc:3-CYANOALANINE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006862 name: 3-dehydro-L-gulonate 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+." [EC:1.1.1.130, MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN] synonym: "2,3-diketo-L-gulonate reductase activity" EXACT [EC:1.1.1.130] synonym: "3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.130] synonym: "3-keto-L-gulonate dehydrogenase activity" EXACT [EC:1.1.1.130] synonym: "3-ketogulonate dehydrogenase activity" EXACT [EC:1.1.1.130] xref: EC:1.1.1.130 xref: GO:0047559 xref: MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006863 name: 3-dehydrosphinganine reductase activity namespace: molecular_function def: "Catalysis of the reaction: sphinganine + NADP+ = 3-dehydrosphinganine + NADPH + H+." [EC:1.1.1.102, MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN] synonym: "3-ketosphinganine reductase activity" EXACT [EC:1.1.1.102] synonym: "3-oxosphinganine reductase activity" EXACT [EC:1.1.1.102] synonym: "3-oxosphinganine:NADPH oxidoreductase activity" EXACT [EC:1.1.1.102] synonym: "D-3-dehydrosphinganine reductase activity" EXACT [EC:1.1.1.102] synonym: "D-3-oxosphinganine reductase activity" EXACT [EC:1.1.1.102] synonym: "D-3-oxosphinganine:B-NADPH oxidoreductase activity" EXACT [EC:1.1.1.102] synonym: "D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.102] synonym: "DSR activity" EXACT [EC:1.1.1.102] synonym: "KTS reductase activity" RELATED [EC:1.1.1.102] xref: EC:1.1.1.102 xref: GO:0047560 xref: MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006864 name: 3-hydroxyanthranilate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2." [EC:1.10.3.5, MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN] synonym: "3-hydroxyanthranilate:oxygen oxidoreductase activity" EXACT [EC:1.10.3.5] synonym: "3-hydroxyanthranilic acid oxidase activity" EXACT [EC:1.10.3.5] xref: EC:1.10.3.5 xref: GO:0047561 xref: MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0006865 name: 3-hydroxyaspartate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = glycine + glyoxylate." [EC:4.1.3.14, MetaCyc:3-HYDROXYASPARTATE-ALDOLASE-RXN] synonym: "erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase activity" EXACT [EC:4.1.3.14] synonym: "erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)" EXACT [EC:4.1.3.14] synonym: "erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase activity" EXACT [EC:4.1.3.14] synonym: "erythro-beta-hydroxyaspartate aldolase activity" EXACT [EC:4.1.3.14] synonym: "erythro-beta-hydroxyaspartate glycine-lyase activity" EXACT [EC:4.1.3.14] xref: EC:4.1.3.14 xref: GO:0047562 xref: MetaCyc:3-HYDROXYASPARTATE-ALDOLASE-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0006866 name: 3-hydroxybenzoate 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxybenzoate + donor-H2 + O2 = 2,3-dihydroxybenzoate + acceptor + H2O." [EC:1.14.99.23, MetaCyc:3-HYDROXYBENZOATE-2-MONOOXYGENASE-RXN] synonym: "3-HBA-2-hydroxylase activity" EXACT [EC:1.14.99.23] synonym: "3-hydroxybenzoate 2-hydroxylase activity" EXACT [] synonym: "3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.99.23] xref: EC:1.14.99.23 xref: GO:0047563 xref: MetaCyc:3-HYDROXYBENZOATE-2-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0006867 name: 3-hydroxycyclohexanone dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxycyclohexanone + acceptor = cyclohexane-1,3-dione + reduced acceptor." [EC:1.1.99.26, MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN] synonym: "3-hydroxycyclohexanone:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.26] xref: EC:1.1.99.26 xref: GO:0047564 xref: MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0006868 name: 3-hydroxypropionate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxypropanoate + NAD+ = 3-oxopropanoate + NADH + H+." [EC:1.1.1.59, MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN] synonym: "3-hydroxypropanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.59] xref: EC:1.1.1.59 xref: GO:0047565 xref: MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006869 name: 3-ketovalidoxylamine C-N-lyase activity namespace: molecular_function def: "Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one." [EC:4.3.3.1, MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN] synonym: "3-ketovalidoxylamine A C-N-lyase activity" EXACT [EC:4.3.3.1] synonym: "4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase [5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one-forming]" RELATED [EC:4.3.3.1] synonym: "4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase activity" EXACT [EC:4.3.3.1] synonym: "p-nitrophenyl-3-ketovalidamine p-nitroaniline lyase activity" EXACT [EC:4.3.3.1] xref: EC:4.3.3.1 xref: GO:0047566 xref: MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN is_a: CCO:F0003408 ! amine-lyase activity [Term] id: CCO:F0006870 name: 3-methyleneoxindole reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-methyloxindole + NADP+ = 3-methyleneoxindole + NADPH + H+." [EC:1.3.1.17, MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN] synonym: "3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.17] synonym: "3-methyloxindole:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.17] xref: EC:1.3.1.17 xref: GO:0047567 xref: MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006871 name: 3-oxo-5-beta-steroid 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor." [EC:1.3.99.6, MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN] synonym: "3-oxo-5beta-steroid 4-dehydrogenase activity" EXACT [EC:1.3.99.6] synonym: "3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase activity" EXACT [EC:1.3.99.6] synonym: "3-oxo-5beta-steroid:acceptor delta4-oxidoreductase activity" EXACT [EC:1.3.99.6] synonym: "delta4-3-ketosteroid 5-beta-reductase activity" EXACT [EC:1.3.99.6] xref: EC:1.3.99.6 xref: GO:0047568 xref: MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN is_a: CCO:F0005255 ! steroid dehydrogenase activity, acting on the CH-CH group of donors [Term] id: CCO:F0006872 name: 3-oxoadipate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA." [EC:2.8.3.6, MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN] subset: gosubset_prok synonym: "3-oxoadipate coenzyme A-transferase activity" EXACT [EC:2.8.3.6] synonym: "3-oxoadipate succinyl-CoA transferase activity" EXACT [EC:2.8.3.6] synonym: "beta-ketoadipate:succinyl-CoA transferase activity" EXACT [EC:2.8.3.6] synonym: "succinyl-CoA:3-oxoadipate CoA-transferase activity" EXACT [EC:2.8.3.6] xref: EC:2.8.3.6 xref: GO:0047569 xref: MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN xref: UM-BBD_enzymeID:e0654 is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0006873 name: 3-oxoadipate enol-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate." [EC:3.1.1.24, MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN] subset: gosubset_prok synonym: "3-ketoadipate enol-lactonase activity" EXACT [EC:3.1.1.24] synonym: "3-oxoadipic enol-lactone hydrolase activity" EXACT [EC:3.1.1.24] synonym: "4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase activity" EXACT [EC:3.1.1.24] synonym: "beta-ketoadipate enol-lactone hydrolase activity" EXACT [EC:3.1.1.24] synonym: "beta-ketoadipic enol-lactone hydrolase activity" EXACT [EC:3.1.1.24] synonym: "carboxymethylbutenolide lactonase activity" EXACT [EC:3.1.1.24] xref: EC:3.1.1.24 xref: GO:0047570 xref: MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006874 name: 3-oxosteroid 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor." [EC:1.3.99.4, MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "1-ene-dehydrogenase activity" EXACT [EC:1.3.99.4] synonym: "3-ketosteroid-1-en-dehydrogenase activity" EXACT [EC:1.3.99.4] synonym: "3-ketosteroid-delta1-dehydrogenase activity" EXACT [EC:1.3.99.4] synonym: "3-oxosteroid delta1-dehydrogenase activity" EXACT [EC:1.3.99.4] synonym: "3-oxosteroid:(2,6-dichlorphenolindophenol) delta1-oxidoreductase activity" EXACT [EC:1.3.99.4] synonym: "3-oxosteroid:(acceptor) delta1-oxidoreductase activity" EXACT [EC:1.3.99.4] synonym: "3-oxosteroid:acceptor delta1-oxidoreductase activity" EXACT [EC:1.3.99.4] synonym: "4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase activity" EXACT [EC:1.3.99.4] synonym: "delta1-dehydrogenase activity" EXACT [EC:1.3.99.4] synonym: "delta1-steroid reductase activity" EXACT [EC:1.3.99.4] xref: EC:1.3.99.4 xref: GO:0047571 xref: MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN is_a: CCO:F0005255 ! steroid dehydrogenase activity, acting on the CH-CH group of donors [Term] id: CCO:F0006875 name: 3-phosphoglycerate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-glycerate 3-phosphate + H2O = D-glycerate + phosphate." [EC:3.1.3.38, MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN] synonym: "3-PGA phosphatase activity" EXACT [EC:3.1.3.38] synonym: "D-3-phosphoglycerate phosphatase activity" EXACT [EC:3.1.3.38] synonym: "D-glycerate-3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.38] xref: EC:3.1.3.38 xref: GO:0047572 xref: MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006876 name: 4-acetamidobutyrate deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate." [EC:3.5.1.63, MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN] synonym: "4-acetamidobutanoate amidohydrolase activity" EXACT [EC:3.5.1.63] xref: EC:3.5.1.63 xref: GO:0047573 xref: MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006877 name: 4-acetamidobutyryl-CoA deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: 4-acetamidobutanoyl + H2O = acetate + 4-aminobutanoyl-CoA." [EC:3.5.1.51, MetaCyc:4-ACETAMIDOBUTYRYL-COA-DEACETYLASE-RXN] synonym: "4-acetamidobutanoyl-CoA amidohydrolase activity" EXACT [EC:3.5.1.51] synonym: "aminobutyryl-CoA thiolesterase activity" EXACT [EC:3.5.1.51] synonym: "deacetylase-thiolesterase activity" EXACT [EC:3.5.1.51] xref: EC:3.5.1.51 xref: GO:0047574 xref: MetaCyc:4-ACETAMIDOBUTYRYL-COA-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006878 name: 4-carboxymuconolactone decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 4,5-dihydro-5-oxofuran-2-acetate + CO2." [EC:4.1.1.44, MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN] subset: gosubset_prok synonym: "4-carboxymonolactone carboxy-lyase activity" EXACT [EC:4.1.1.44] synonym: "4-carboxymuconolactone carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming)" EXACT [EC:4.1.1.44] synonym: "4-carboxymuconolactone carboxy-lyase activity" EXACT [EC:4.1.1.44] synonym: "gamma-4-carboxymuconolactone decarboxylase activity" EXACT [EC:4.1.1.44] xref: EC:4.1.1.44 xref: GO:0047575 xref: MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006879 name: 4-chlorobenzoate dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride." [EC:3.8.1.6, MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN] synonym: "4-chlorobenzoate chlorohydrolase activity" EXACT [EC:3.8.1.6] synonym: "halobenzoate dehalogenase activity" EXACT [EC:3.8.1.6] xref: EC:3.8.1.6 xref: GO:0047576 xref: MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0006880 name: 4-hydroxybutyrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxybutanoate + NAD+ = succinate semialdehyde + NADH + H+." [EC:1.1.1.61, MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "4-hydroxybutanoate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.61] synonym: "gamma-hydroxybutyrate dehydrogenase activity" EXACT [EC:1.1.1.61] xref: EC:1.1.1.61 xref: GO:0047577 xref: MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006881 name: 4-hydroxyglutamate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate." [EC:2.6.1.23, MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN] synonym: "4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.23] synonym: "4-hydroxyglutamate aminotransferase activity" EXACT [] xref: EC:2.6.1.23 xref: GO:0047578 xref: MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006882 name: 4-hydroxymandelate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2." [EC:1.1.3.19, MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN] synonym: "(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.19] synonym: "L-4-hydroxymandelate oxidase (decarboxylating)" EXACT [EC:1.1.3.19] xref: EC:1.1.3.19 xref: GO:0047579 xref: MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0006883 name: 4-hydroxyproline epimerase activity namespace: molecular_function def: "Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline." [EC:5.1.1.8, MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN] synonym: "4-hydroxyproline 2-epimerase activity" EXACT [EC:5.1.1.8] synonym: "hydroxyproline 2-epimerase activity" EXACT [EC:5.1.1.8] synonym: "hydroxyproline epimerase activity" EXACT [EC:5.1.1.8] synonym: "L-hydroxyproline epimerase activity" EXACT [EC:5.1.1.8] xref: EC:5.1.1.8 xref: GO:0047580 xref: MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0006884 name: 4-methyleneglutamate-ammonia ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-methylene-L-glutamate + NH3 = AMP + diphosphate + 4-methylene-L-glutamine." [EC:6.3.1.7, MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN] subset: gosubset_prok synonym: "4-methylene-L-glutamate:ammonia ligase (AMP-forming)" EXACT [EC:6.3.1.7] synonym: "4-methyleneglutamine synthetase activity" EXACT [EC:6.3.1.7] xref: EC:6.3.1.7 xref: GO:0047581 xref: MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0006885 name: 4-methyleneglutaminase activity namespace: molecular_function def: "Catalysis of the reaction: 4-methylene-L-glutamine + H2O = 4-methylene-L-glutamate + NH3." [EC:3.5.1.67, MetaCyc:4-METHYLENEGLUTAMINASE-RXN] synonym: "4-methylene-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.67] synonym: "4-methyleneglutamine amidohydrolase activity" EXACT [EC:3.5.1.67] synonym: "4-methyleneglutamine deamidase activity" EXACT [EC:3.5.1.67] xref: EC:3.5.1.67 xref: GO:0047582 xref: MetaCyc:4-METHYLENEGLUTAMINASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006886 name: 4-methyloxaloacetate esterase activity namespace: molecular_function def: "Catalysis of the reaction: oxaloacetate 4-methyl ester + H2O = oxaloacetate + methanol." [EC:3.1.1.44, MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN] synonym: "oxaloacetate-4-methyl-ester oxaloacetohydrolase activity" EXACT [EC:3.1.1.44] xref: EC:3.1.1.44 xref: GO:0047583 xref: MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006887 name: 4-oxalmesaconate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H2O." [EC:4.2.1.83, MetaCyc:4-OXALMESACONATE-HYDRATASE-RXN] subset: gosubset_prok synonym: "2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase [(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]" RELATED [EC:4.2.1.83] synonym: "2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity" EXACT [EC:4.2.1.83] synonym: "4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity" EXACT [EC:4.2.1.83] synonym: "4-carboxy-2-oxohexenedioate hydratase activity" EXACT [EC:4.2.1.83] synonym: "gamma-oxalmesaconate hydratase activity" EXACT [EC:4.2.1.83] synonym: "oxalmesaconate hydratase activity" EXACT [EC:4.2.1.83] xref: EC:4.2.1.83 xref: GO:0047584 xref: MetaCyc:4-OXALMESACONATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006888 name: 4-pyridoxolactonase activity namespace: molecular_function def: "Catalysis of the reaction: 4-pyridoxolactone + H2O = 4-pyridoxate." [EC:3.1.1.27, MetaCyc:4-PYRIDOXOLACTONASE-RXN] synonym: "4-pyridoxolactone lactonohydrolase activity" EXACT [EC:3.1.1.27] xref: EC:3.1.1.27 xref: GO:0047585 xref: MetaCyc:4-PYRIDOXOLACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006889 name: 5'-acylphosphoadenosine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate." [EC:3.6.1.20, MetaCyc:5] synonym: "5'-acylphosphoadenosine acylhydrolase activity" EXACT [EC:3.6.1.20] synonym: "5-phosphoadenosine hydrolase activity" EXACT [EC:3.6.1.20] xref: EC:3.6.1.20 xref: GO:0047586 xref: MetaCyc:5 is_a: CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Term] id: CCO:F0006890 name: 5-alpha-hydroxysteroid dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 5-alpha-ergosta-7,22-diene-3-beta,5-diol = ergosterol + H2O." [EC:4.2.1.62, MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN] synonym: "5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming)" EXACT [EC:4.2.1.62] synonym: "5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase activity" EXACT [EC:4.2.1.62] synonym: "5alpha-hydroxysteroid dehydratase activity" EXACT [EC:4.2.1.62] xref: EC:4.2.1.62 xref: GO:0047587 xref: MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006891 name: 5-aminopentanamidase activity namespace: molecular_function def: "Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3." [EC:3.5.1.30, MetaCyc:5-AMINOPENTANAMIDASE-RXN] synonym: "5-aminonorvaleramidase activity" EXACT [EC:3.5.1.30] synonym: "5-aminopentanamide amidohydrolase activity" EXACT [EC:3.5.1.30] synonym: "5-aminovaleramidase activity" EXACT [EC:3.5.1.30] xref: EC:3.5.1.30 xref: GO:0047588 xref: MetaCyc:5-AMINOPENTANAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006892 name: 5-aminovalerate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate." [EC:2.6.1.48, MetaCyc:5-AMINOVALERATE-AMINOTRANSFERASE-RXN] synonym: "5-aminopentanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.48] synonym: "5-aminovalerate aminotransferase activity" EXACT [] synonym: "delta-aminovalerate aminotransferase activity" EXACT [EC:2.6.1.48] synonym: "delta-aminovalerate transaminase activity" EXACT [EC:2.6.1.48] xref: EC:2.6.1.48 xref: GO:0047589 xref: MetaCyc:5-AMINOVALERATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006893 name: 5-dehydro-2-deoxygluconokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate." [EC:2.7.1.92, MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN] subset: gosubset_prok synonym: "5-keto-2-deoxyglucono kinase (phosphorylating)" EXACT [EC:2.7.1.92] synonym: "5-keto-2-deoxygluconokinase activity" EXACT [EC:2.7.1.92] synonym: "ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.92] synonym: "DKH kinase activity" EXACT [EC:2.7.1.92] xref: EC:2.7.1.92 xref: GO:0047590 xref: MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006894 name: 5-hydroxypentanoate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + 5-hydroxypentanoate = acetate + 5-hydroxy-pentanoyl-CoA." [EC:2.8.3.14, MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN] synonym: "5-hydroxyvalerate CoA-transferase activity" EXACT [EC:2.8.3.14] synonym: "5-hydroxyvalerate coenzyme A transferase activity" EXACT [EC:2.8.3.14] synonym: "acetyl-CoA:5-hydroxypentanoate CoA-transferase activity" EXACT [EC:2.8.3.14] xref: EC:2.8.3.14 xref: GO:0047591 xref: MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0006895 name: 5-pyridoxate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + H+ + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+." [EC:1.14.12.5, MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN] synonym: "5-pyridoxate oxidase activity" EXACT [EC:1.14.12.5] synonym: "5-pyridoxate,NADPH:oxygen oxidoreductase (decyclizing)" EXACT [EC:1.14.12.5] xref: EC:1.14.12.5 xref: GO:0047592 xref: MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0006896 name: 6-acetylglucose deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: 6-acetyl-D-glucose + H2O = D-glucose + acetate." [EC:3.1.1.33, MetaCyc:6-ACETYLGLUCOSE-DEACETYLASE-RXN] synonym: "6-acetyl-D-glucose acetylhydrolase activity" EXACT [EC:3.1.1.33] synonym: "6-O-acetylglucose deacetylase activity" EXACT [EC:3.1.1.33] xref: EC:3.1.1.33 xref: GO:0047593 xref: MetaCyc:6-ACETYLGLUCOSE-DEACETYLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006897 name: 6-beta-hydroxyhyoscyamine epoxidase activity namespace: molecular_function def: "Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = scopolamine + succinate + CO2." [EC:1.14.11.14, MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN] synonym: "(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming)" EXACT [EC:1.14.11.14] synonym: "6beta-hydroxyhyoscyamine epoxidase activity" EXACT [EC:1.14.11.14] synonym: "hydroxyhyoscyamine dioxygenase activity" EXACT [EC:1.14.11.14] xref: EC:1.14.11.14 xref: GO:0047594 xref: MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0006898 name: 6-hydroxynicotinate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin." [EC:1.3.7.1, MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN] synonym: "1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.1] synonym: "6-hydroxynicotinic reductase activity" EXACT [EC:1.3.7.1] synonym: "6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.1] synonym: "6-oxotetrahydro-nicotinate dehydrogenase activity" EXACT [EC:1.3.7.1] synonym: "6-oxotetrahydronicotinate dehydrogenase activity" EXACT [EC:1.3.7.1] synonym: "HNA reductase activity" EXACT [EC:1.3.7.1] xref: EC:1.3.7.1 xref: GO:0047595 xref: MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN is_a: CCO:F0003237 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0006899 name: 6-methylsalicylate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 6-methylsalicylate = 3-cresol + CO2." [EC:4.1.1.52, MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN] synonym: "6-methylsalicylate carboxy-lyase (3-cresol-forming)" EXACT [EC:4.1.1.52] synonym: "6-methylsalicylate carboxy-lyase activity" EXACT [EC:4.1.1.52] synonym: "6-methylsalicylic acid (2,6-cresotic acid) decarboxylase activity" EXACT [EC:4.1.1.52] synonym: "6-MSA decarboxylase activity" EXACT [EC:4.1.1.52] xref: EC:4.1.1.52 xref: GO:0047596 xref: MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006900 name: 6-oxocineole dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 6-oxocineole + NADPH + H+ + O2 = 1,6,6-trimethyl-2,7-dioxabicyclo-[3.2.2]nonan-3-one + NADP+ + H2O." [EC:1.14.13.51, MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN] synonym: "6-oxocineole oxygenase activity" EXACT [EC:1.14.13.51] synonym: "6-oxocineole,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.51] xref: EC:1.14.13.51 xref: GO:0047597 xref: MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006901 name: 7-dehydrocholesterol reductase activity namespace: molecular_function def: "Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+." [EC:1.3.1.21, MetaCyc:7-DEHYDROCHOLESTEROL-REDUCTASE-RXN] synonym: "7-DHC reductase activity" EXACT [EC:1.3.1.21] synonym: "cholesterol:NADP+ delta7-oxidoreductase activity" EXACT [EC:1.3.1.21] synonym: "sterol Delta(7)-reductase activity" BROAD [EC:1.3.1.21] synonym: "sterol delta7-reductase activity" EXACT [EC:1.3.1.21] xref: EC:1.3.1.21 xref: GO:0047598 xref: MetaCyc:7-DEHYDROCHOLESTEROL-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006902 name: 8-oxocoformycin reductase activity namespace: molecular_function def: "Catalysis of the reaction: coformycin + NADP+ = 8-oxocoformycin + NADPH + H+." [EC:1.1.1.235, MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN] synonym: "8-ketodeoxycoformycin reductase activity" EXACT [EC:1.1.1.235] synonym: "coformycin:NADP+ 8-oxidoreductase activity" EXACT [EC:1.1.1.235] xref: EC:1.1.1.235 xref: GO:0047599 xref: MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006903 name: abequosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid." [EC:2.4.1.60, MetaCyc:ABEQUOSYLTRANSFERASE-RXN] synonym: "CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase activity" EXACT [EC:2.4.1.60] synonym: "trihexose diphospholipid abequosyltransferase activity" EXACT [EC:2.4.1.60] xref: EC:2.4.1.60 xref: GO:0047600 xref: MetaCyc:ABEQUOSYLTRANSFERASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006904 name: acetate kinase (diphosphate) activity namespace: molecular_function def: "Catalysis of the reaction: diphosphate + acetate = phosphate + acetyl phosphate." [EC:2.7.2.12, MetaCyc:ACETATE-KINASE-(PYROPHOSPHATE)-RXN] synonym: "acetate kinase (pyrophosphate) activity" EXACT [EC:2.7.2.12] synonym: "diphosphate:acetate phosphotransferase activity" EXACT [EC:2.7.2.12] synonym: "pyrophosphate-acetate phosphotransferase activity" EXACT [EC:2.7.2.12] xref: EC:2.7.2.12 xref: GO:0047601 xref: MetaCyc:ACETATE-KINASE-(PYROPHOSPHATE)-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0006905 name: acetoacetate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: acetoacetate + H+ = acetone + CO2." [EC:4.1.1.4, MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN] subset: gosubset_prok synonym: "acetoacetate carboxy-lyase (acetone-forming)" EXACT [EC:4.1.1.4] synonym: "acetoacetate carboxy-lyase activity" EXACT [EC:4.1.1.4] synonym: "acetoacetic acid decarboxylase activity" EXACT [EC:4.1.1.4] xref: EC:4.1.1.4 xref: GO:0047602 xref: MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006906 name: acetoacetyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: acetoacetyl-CoA + H2O = CoA + acetoacetate." [EC:3.1.2.11, MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN] synonym: "acetoacetyl CoA deacylase activity" EXACT [EC:3.1.2.11] synonym: "acetoacetyl coenzyme A deacylase activity" EXACT [EC:3.1.2.11] synonym: "acetoacetyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.11] xref: EC:3.1.2.11 xref: GO:0047603 xref: MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0006907 name: acetoin racemase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-acetoin = (R)-acetoin." [EC:5.1.2.4, MetaCyc:ACETOIN-RACEMASE-RXN] synonym: "acetylmethylcarbinol racemase activity" EXACT [EC:5.1.2.4] xref: EC:5.1.2.4 xref: GO:0047604 xref: MetaCyc:ACETOIN-RACEMASE-RXN is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0006908 name: acetolactate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2." [EC:4.1.1.5, MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN] subset: gosubset_prok synonym: "(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]" RELATED [EC:4.1.1.5] synonym: "(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity" EXACT [EC:4.1.1.5] synonym: "alpha-acetolactate decarboxylase activity" EXACT [EC:4.1.1.5] xref: EC:4.1.1.5 xref: GO:0047605 xref: MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006909 name: acetone-cyanhydrin lyase activity namespace: molecular_function def: "Catalysis of the reaction: acetone cyanhydrin = cyanide + acetone." [EC:4.1.2.37, MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN] synonym: "acetone-cyanohydrin acetone-lyase (cyanide-forming)" EXACT [EC:4.1.2.37] synonym: "acetone-cyanohydrin acetone-lyase activity" EXACT [EC:4.1.2.37] synonym: "acetone-cyanohydrin lyase activity" EXACT [] synonym: "alpha-hydroxynitrile lyase activity" EXACT [EC:4.1.2.37] xref: EC:4.1.2.37 xref: GO:0047606 xref: MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006910 name: acetylindoxyl oxidase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown." [EC:1.7.3.2, MetaCyc:ACETYLINDOXYL-OXIDASE-RXN] synonym: "N-acetylindoxyl:oxygen oxidoreductase activity" EXACT [EC:1.7.3.2] xref: EC:1.7.3.2 xref: GO:0047608 xref: MetaCyc:ACETYLINDOXYL-OXIDASE-RXN is_a: CCO:F0003258 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor [Term] id: CCO:F0006911 name: acetylputrescine deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetylputrescine + H2O = acetate + putrescine." [EC:3.5.1.62, MetaCyc:ACETYLPUTRESCINE-DEACETYLASE-RXN] synonym: "N-acetylputrescine acetylhydrolase activity" EXACT [EC:3.5.1.62] xref: EC:3.5.1.62 xref: GO:0047609 xref: MetaCyc:ACETYLPUTRESCINE-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006912 name: acetylsalicylate deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: acetylsalicylate + H2O = salicylate + acetate." [EC:3.1.1.55, MetaCyc:ACETYLSALICYLATE-DEACETYLASE-RXN] synonym: "acetylsalicylate O-acetylhydrolase activity" EXACT [EC:3.1.1.55] synonym: "acetylsalicylic acid esterase activity" EXACT [EC:3.1.1.55] synonym: "aspirin esterase activity" EXACT [EC:3.1.1.55] synonym: "aspirin hydrolase activity" EXACT [EC:3.1.1.55] xref: EC:3.1.1.55 xref: GO:0047610 xref: MetaCyc:ACETYLSALICYLATE-DEACETYLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006913 name: acetylspermidine deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N1-acetylspermidine + H2O = acetate + spermidine." [EC:3.5.1.48, MetaCyc:ACETYLSPERMIDINE-DEACETYLASE-RXN] subset: gosubset_prok synonym: "8-N-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] synonym: "N(1)-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] synonym: "N(8)-acetylspermidine amidohydrolase activity" RELATED [EC:3.5.1.48] synonym: "N(8)-acetylspermidine deacetylase activity" RELATED [EC:3.5.1.48] synonym: "N(8)-monoacetylspermidine deacetylase activity" RELATED [EC:3.5.1.48] synonym: "N-acetylspermidine deacetylase activity" BROAD [EC:3.5.1.48] synonym: "N1-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] synonym: "N8-acetylspermidine amidohydrolase activity" EXACT [EC:3.5.1.48] synonym: "N8-acetylspermidine deacetylase activity" EXACT [EC:3.5.1.48] synonym: "N8-monoacetylspermidine deacetylase activity" EXACT [EC:3.5.1.48] xref: EC:3.5.1.48 xref: GO:0047611 xref: MetaCyc:ACETYLSPERMIDINE-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0006914 name: acid-CoA ligase (GDP-forming) activity namespace: molecular_function def: "Catalysis of the reaction: GTP + an acid + CoA = GDP + phosphate + acyl-CoA." [EC:6.2.1.10, MetaCyc:ACID--COA-LIGASE-(GDP-FORMING)-RXN] synonym: "acid:CoA ligase (GDP-forming)" EXACT [EC:6.2.1.10] synonym: "acyl coenzyme A synthetase (guanosine diphosphate forming)" EXACT [EC:6.2.1.10] synonym: "acyl-CoA synthetase (GDP-forming) activity" EXACT [EC:6.2.1.10] xref: EC:6.2.1.10 xref: GO:0047612 xref: MetaCyc:ACID--COA-LIGASE-(GDP-FORMING)-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0006915 name: aconitate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: cis-aconitate = itaconate + CO2." [EC:4.1.1.6, MetaCyc:ACONITATE-DECARBOXYLASE-RXN] synonym: "CAD activity" BROAD [EC:4.1.1.6] synonym: "cis-aconitate carboxy-lyase (itaconate-forming)" EXACT [EC:4.1.1.6] synonym: "cis-aconitate carboxy-lyase activity" EXACT [EC:4.1.1.6] synonym: "cis-aconitic decarboxylase activity" EXACT [EC:4.1.1.6] xref: EC:4.1.1.6 xref: GO:0047613 xref: MetaCyc:ACONITATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006916 name: aconitate delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: trans-aconitate = cis-aconitate." [EC:5.3.3.7, MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN] synonym: "aconitate D-isomerase activity" EXACT [] synonym: "aconitate delta2-delta3-isomerase activity" EXACT [EC:5.3.3.7] synonym: "aconitate isomerase activity" BROAD [EC:5.3.3.7] xref: EC:5.3.3.7 xref: GO:0047614 xref: MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0006917 name: actinomycin lactonase activity namespace: molecular_function def: "Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone." [EC:3.1.1.39, MetaCyc:ACTINOMYCIN-LACTONASE-RXN] synonym: "actinomycin lactonohydrolase activity" EXACT [EC:3.1.1.39] xref: EC:3.1.1.39 xref: GO:0047615 xref: MetaCyc:ACTINOMYCIN-LACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006918 name: acyl-CoA dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+." [EC:1.3.1.8, MetaCyc:ACYL-COA-DEHYDROGENASE-(NADP+)-RXN] synonym: "2-enoyl-CoA reductase activity" EXACT [EC:1.3.1.8] synonym: "acyl-CoA:NADP+ 2-oxidoreductase activity" EXACT [EC:1.3.1.8] synonym: "crotonyl coenzyme A reductase activity" EXACT [EC:1.3.1.8] synonym: "dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.3.1.8] synonym: "enoyl coenzyme A reductase activity" EXACT [EC:1.3.1.8] xref: EC:1.3.1.8 xref: GO:0047616 xref: MetaCyc:ACYL-COA-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006919 name: acyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate." [EC:3.1.2.20, MetaCyc:ACYL-COA-HYDROLASE-RXN] subset: gosubset_prok synonym: "acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.20] synonym: "acyl coenzyme A thioesterase activity" EXACT [EC:3.1.2.20] synonym: "thioesterase B" RELATED [EC:3.1.2.20] synonym: "thioesterase II" RELATED [EC:3.1.2.20] xref: EC:3.1.2.20 xref: GO:0047617 xref: MetaCyc:ACYL-COA-HYDROLASE-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0006920 name: acylagmatine amidase activity namespace: molecular_function def: "Catalysis of the reaction: benzoylagmatine + H2O = benzoate + agmatine." [EC:3.5.1.40, MetaCyc:ACYLAGMATINE-AMIDASE-RXN] synonym: "acylagmatine amidohydrolase activity" EXACT [EC:3.5.1.40] synonym: "acylagmatine deacylase activity" EXACT [EC:3.5.1.40] synonym: "benzoylagmatine amidohydrolase activity" EXACT [EC:3.5.1.40] xref: EC:3.5.1.40 xref: GO:0047618 xref: MetaCyc:ACYLAGMATINE-AMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006921 name: acylcarnitine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine." [EC:3.1.1.28, MetaCyc:ACYLCARNITINE-HYDROLASE-RXN] synonym: "carnitine ester hydrolase activity" EXACT [EC:3.1.1.28] synonym: "HACH" RELATED [EC:3.1.1.28] synonym: "high activity acylcarnitine hydrolase activity" EXACT [EC:3.1.1.28] synonym: "long-chain acyl-L-carnitine hydrolase activity" EXACT [EC:3.1.1.28] synonym: "O-acylcarnitine acylhydrolase activity" EXACT [EC:3.1.1.28] synonym: "palmitoyl carnitine hydrolase activity" EXACT [EC:3.1.1.28] synonym: "palmitoyl-L-carnitine hydrolase activity" EXACT [EC:3.1.1.28] synonym: "palmitoylcarnitine hydrolase activity" EXACT [EC:3.1.1.28] xref: EC:3.1.1.28 xref: GO:0047619 xref: MetaCyc:ACYLCARNITINE-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006922 name: acylglycerol kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate." [EC:2.7.1.94, MetaCyc:ACYLGLYCEROL-KINASE-RXN] synonym: "ATP:acylglycerol 3-phosphotransferase activity" EXACT [EC:2.7.1.94] synonym: "MGK" RELATED [EC:2.7.1.94] synonym: "monoacylglycerol kinase (phosphorylating)" EXACT [EC:2.7.1.94] synonym: "monoacylglycerol kinase activity" EXACT [EC:2.7.1.94] synonym: "monoglyceride kinase activity" EXACT [EC:2.7.1.94] synonym: "monoglyceride phosphokinase activity" EXACT [EC:2.7.1.94] synonym: "sn-2-monoacylglycerol kinase activity" EXACT [EC:2.7.1.94] xref: EC:2.7.1.94 xref: GO:0047620 xref: MetaCyc:ACYLGLYCEROL-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006923 name: acylpyruvate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate." [EC:3.7.1.5, MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN] subset: gosubset_prok synonym: "3-acylpyruvate acylhydrolase activity" EXACT [EC:3.7.1.5] xref: EC:3.7.1.5 xref: GO:0047621 xref: MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN xref: UM-BBD_enzymeID:e0868 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0006924 name: adenosine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine + H2O = D-ribose + adenine." [EC:3.2.2.7, MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN] synonym: "adenosinase activity" EXACT [EC:3.2.2.7] synonym: "adenosine hydrolase activity" EXACT [EC:3.2.2.7] synonym: "adenosine ribohydrolase activity" EXACT [EC:3.2.2.7] synonym: "ANase activity" EXACT [EC:3.2.2.7] synonym: "N-ribosyladenine ribohydrolase activity" EXACT [EC:3.2.2.7] xref: EC:3.2.2.7 xref: GO:0047622 xref: MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0006925 name: adenosine-phosphate deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-AMP + H2O = 5'-IMP + NH3." [EC:3.5.4.17, MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN] synonym: "adenine nucleotide deaminase activity" EXACT [EC:3.5.4.17] synonym: "adenosine (phosphate) deaminase activity" EXACT [EC:3.5.4.17] synonym: "adenosine-phosphate aminohydrolase activity" EXACT [EC:3.5.4.17] xref: EC:3.5.4.17 xref: GO:0047623 xref: MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0006926 name: adenosine-tetraphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate." [EC:3.6.1.14, MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN] subset: gosubset_prok synonym: "adenosine-tetraphosphate phosphohydrolase activity" EXACT [EC:3.6.1.14] xref: EC:3.6.1.14 xref: GO:0047624 xref: MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0006927 name: adenosylmethionine cyclotransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine = 5'-methylthioadenosine + 2-aminobutan-4-olide." [EC:2.5.1.4, MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN] synonym: "adenosyl methionine cyclotransferase activity" EXACT [] synonym: "adenosylmethioninase activity" EXACT [EC:2.5.1.4] synonym: "S-adenosyl-L-methionine alkyltransferase (cyclizing)" EXACT [EC:2.5.1.4] xref: EC:2.5.1.4 xref: GO:0047625 xref: MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006928 name: adenosylmethionine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + S-adenosyl-L-methionine = L-homoserine + methylthioadenosine." [EC:3.3.1.2, MetaCyc:ADENOSYLMETHIONINE-HYDROLASE-RXN] synonym: "adenosyl methionine hydrolase activity" EXACT [] synonym: "adenosylmethionine lyase activity" EXACT [EC:3.3.1.2] synonym: "methylmethionine-sulfonium-salt hydrolase activity" EXACT [EC:3.3.1.2] synonym: "S-adenosyl-L-methionine hydrolase activity" EXACT [EC:3.3.1.2] synonym: "S-adenosylmethionine cleaving enzyme activity" EXACT [EC:3.3.1.2] xref: EC:3.3.1.2 xref: GO:0047626 xref: MetaCyc:ADENOSYLMETHIONINE-HYDROLASE-RXN is_a: CCO:F0003372 ! trialkylsulfonium hydrolase activity [Term] id: CCO:F0006929 name: adenylylsulfatase activity namespace: molecular_function def: "Catalysis of the reaction: adenylylsulfate + H2O = AMP + SO4(2-) (sulfate)." [EC:3.6.2.1, MetaCyc:ADENYLYLSULFATASE-RXN] synonym: "adenosine 5-phosphosulfate sulfohydrolase activity" EXACT [EC:3.6.2.1] synonym: "adenylylsulfate sulfohydrolase activity" EXACT [EC:3.6.2.1] synonym: "adenylylsulphatase activity" EXACT [] xref: EC:3.6.2.1 xref: GO:0047627 xref: MetaCyc:ADENYLYLSULFATASE-RXN is_a: CCO:F0003387 ! hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides [Term] id: CCO:F0006930 name: ADP-thymidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate." [EC:2.7.1.118, MetaCyc:ADP--THYMIDINE-KINASE-RXN] synonym: "adenosine diphosphate-thymidine phosphotransferase activity" EXACT [EC:2.7.1.118] synonym: "ADP:dThd phosphotransferase activity" EXACT [EC:2.7.1.118] synonym: "ADP:thymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.118] xref: EC:2.7.1.118 xref: GO:0047628 xref: MetaCyc:ADP--THYMIDINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006931 name: ADP deaminase activity namespace: molecular_function def: "Catalysis of the reaction: ADP + H2O = IDP + NH3." [EC:3.5.4.7, MetaCyc:ADP-DEAMINASE-RXN] synonym: "adenosine diphosphate deaminase activity" EXACT [EC:3.5.4.7] synonym: "adenosinepyrophosphate deaminase activity" EXACT [EC:3.5.4.7] synonym: "ADP aminohydrolase activity" EXACT [EC:3.5.4.7] xref: EC:3.5.4.7 xref: GO:0047629 xref: MetaCyc:ADP-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0006932 name: ADP-phosphoglycerate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 3-(ADP)-2-phosphoglycerate + H2O = 3-(ADP)-glycerate + phosphate." [EC:3.1.3.28, MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN] synonym: "3-(ADP)-2-phosphoglycerate phosphohydrolase activity" EXACT [EC:3.1.3.28] synonym: "adenosine diphosphate phosphoglycerate phosphatase activity" EXACT [EC:3.1.3.28] synonym: "ADPphosphoglycerate phosphatase activity" EXACT [EC:3.1.3.28] xref: EC:3.1.3.28 xref: GO:0047630 xref: MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006933 name: ADP-ribose diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate." [EC:3.6.1.13, MetaCyc:ADP-RIBOSE-PYROPHOSPHATASE-RXN] subset: gosubset_prok synonym: "adenosine diphosphoribose pyrophosphatase activity" EXACT [] synonym: "ADP-ribose phosphohydrolase activity" EXACT [] synonym: "ADP-ribose pyrophosphatase activity" EXACT [] synonym: "ADP-ribose ribophosphohydrolase activity" EXACT [EC:3.6.1.13] synonym: "ADPR-PPase activity" EXACT [] synonym: "ADPribose diphosphatase activity" EXACT [EC:3.6.1.13] synonym: "ADPribose pyrophosphatase activity" EXACT [EC:3.6.1.13] xref: EC:3.6.1.13 xref: GO:0047631 xref: MetaCyc:RXN0-1441 is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0006934 name: agmatine deiminase activity namespace: molecular_function def: "Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3." [EC:3.5.3.12, MetaCyc:AGMATINE-DEIMINASE-RXN] subset: gosubset_prok synonym: "agmatine amidinohydrolase" BROAD [EC:3.5.3.12] synonym: "agmatine iminohydrolase activity" EXACT [EC:3.5.3.12] xref: EC:3.5.3.12 xref: GO:0047632 xref: MetaCyc:AGMATINE-DEIMINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0006935 name: agmatine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + agmatine = ADP + N4-phosphoagmatine." [EC:2.7.3.10, MetaCyc:AGMATINE-KINASE-RXN] synonym: "ATP:agmatine 4-N-phosphotransferase activity" EXACT [EC:2.7.3.10] synonym: "ATP:agmatine N4-phosphotransferase activity" EXACT [EC:2.7.3.10] synonym: "phosphagen phosphokinase activity" RELATED [EC:2.7.3.10] xref: EC:2.7.3.10 xref: GO:0047633 xref: MetaCyc:AGMATINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0006936 name: agmatine N4-coumaroyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = CoA + N-(4-guanidinobutyl)-N4-hydroxycinnamamide." [EC:2.3.1.64, MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN] synonym: "4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase activity" EXACT [EC:2.3.1.64] synonym: "4-coumaroyl-CoA:agmatine N4-coumaroyltransferase activity" EXACT [EC:2.3.1.64] synonym: "agmatine coumaroyltransferase activity" EXACT [EC:2.3.1.64] synonym: "p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase activity" EXACT [EC:2.3.1.64] xref: EC:2.3.1.64 xref: GO:0047634 xref: MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006937 name: alanine-oxo-acid transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid." [EC:2.6.1.12, MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN] synonym: "alanine--oxo-acid aminotransferase activity" EXACT [EC:2.6.1.12] synonym: "alanine-keto acid aminotransferase activity" EXACT [EC:2.6.1.12] synonym: "alanine-oxo acid aminotransferase activity" EXACT [EC:2.6.1.12] synonym: "alanine-oxo-acid aminotransferase activity" EXACT [] synonym: "L-alanine-alpha-keto acid aminotransferase activity" EXACT [EC:2.6.1.12] synonym: "L-alanine:2-oxo-acid aminotransferase activity" EXACT [EC:2.6.1.12] synonym: "leucine-alanine transaminase activity" EXACT [EC:2.6.1.12] xref: EC:2.6.1.12 xref: GO:0047635 xref: MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006938 name: alanopine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,2'-iminodipropanoate + NAD+ + H2O = L-alanine + pyruvate + NADH." [EC:1.5.1.17, MetaCyc:ALANOPINE-DEHYDROGENASE-RXN] synonym: "2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming)" EXACT [EC:1.5.1.17] synonym: "ADH" RELATED [EC:1.5.1.17] synonym: "alanopine: NAD oxidoreductase activity" EXACT [EC:1.5.1.17] synonym: "alanopine:NAD oxidoreductase activity" EXACT [EC:1.5.1.17] synonym: "alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase activity" EXACT [EC:1.5.1.17] synonym: "ALPDH" RELATED [EC:1.5.1.17] synonym: "meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase activity" EXACT [EC:1.5.1.17] xref: EC:1.5.1.17 xref: GO:0047636 xref: MetaCyc:ALANOPINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006939 name: alanylphosphatidylglycerol synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol." [EC:2.3.2.11, MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN] synonym: "alanyl phosphatidylglycerol synthetase activity" EXACT [EC:2.3.2.11] synonym: "L-alanyl-tRNA:phosphatidylglycerol alanyltransferase activity" EXACT [EC:2.3.2.11] synonym: "O-alanylphosphatidylglycerol synthase activity" EXACT [EC:2.3.2.11] xref: EC:2.3.2.11 xref: GO:0047637 xref: MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0006940 name: albendazole monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: albendazole + NADPH + O2 = albendazole S-oxide + NADP+ + H2O." [EC:1.14.13.32, MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN] synonym: "albendazole oxidase activity" EXACT [EC:1.14.13.32] synonym: "albendazole sulfoxidase activity" EXACT [EC:1.14.13.32] synonym: "albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)" EXACT [EC:1.14.13.32] xref: EC:1.14.13.32 xref: GO:0047638 xref: MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006941 name: alcohol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2." [EC:1.1.3.13, MetaCyc:ALCOHOL-OXIDASE-RXN] comment: Note that the enzyme alcohol oxidase also has methanol oxidase activity (GO:0046563). synonym: "alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.13] synonym: "AOX activity" EXACT [EC:1.1.3.13] synonym: "ethanol oxidase activity" EXACT [EC:1.1.3.13] xref: EC:1.1.3.13 xref: GO:0047639 xref: MetaCyc:ALCOHOL-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0006942 name: aldose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH." [EC:1.1.1.121, MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN] synonym: "aldose dehydrogenase activity" EXACT [EC:1.1.1.121] synonym: "D-aldose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.121] synonym: "dehydrogenase, D-aldohexose" EXACT [EC:1.1.1.121] xref: EC:1.1.1.121 xref: GO:0047640 xref: MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006943 name: aldose-6-phosphate reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: D-sorbitol 6-phosphate + NADP+ = D-glucose 6-phosphate + NADPH." [EC:1.1.1.200, MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-(NADPH)-RXN] synonym: "A6PR" RELATED [EC:1.1.1.200] synonym: "alditol 6-phosphate:NADP 1-oxidoreductase activity" EXACT [EC:1.1.1.200] synonym: "aldose 6-phosphate reductase activity" EXACT [EC:1.1.1.200] synonym: "aldose-6-P reductase activity" EXACT [EC:1.1.1.200] synonym: "aldose-6-phosphate reductase activity" EXACT [EC:1.1.1.200] synonym: "D-aldose-6-phosphate:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.200] synonym: "NADP-dependent aldose 6-phosphate reductase activity" EXACT [EC:1.1.1.200] synonym: "NADP-dependent D-sorbitol-6-phosphate dehydrogenase activity" EXACT [EC:1.1.1.200] xref: EC:1.1.1.200 xref: GO:0047641 xref: MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-(NADPH)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006944 name: aldose beta-D-fructosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside." [EC:2.4.1.162, MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN] synonym: "aldose b-D-fructosyltransferase activity" EXACT [] synonym: "alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.162] xref: EC:2.4.1.162 xref: GO:0047642 xref: MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN is_a: CCO:F0008006 ! fructosyltransferase activity [Term] id: CCO:F0006945 name: alginate synthase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1)." [EC:2.4.1.33, MetaCyc:ALGINATE-SYNTHASE-RXN] synonym: "GDP-D-mannuronate:alginate D-mannuronyltransferase activity" EXACT [EC:2.4.1.33] synonym: "mannuronosyl transferase activity" EXACT [EC:2.4.1.33] xref: EC:2.4.1.33 xref: GO:0047643 xref: MetaCyc:ALGINATE-SYNTHASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006946 name: alizarin 2-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + alizarin = UDP + 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone." [EC:2.4.1.103, MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "alizarin 2-b-glucosyltransferase activity" EXACT [] synonym: "UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.103] synonym: "UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyl-transferase activity" EXACT [EC:2.4.1.103] synonym: "uridine diphosphoglucose-alizarin glucosyltransferase activity" EXACT [EC:2.4.1.103] xref: EC:2.4.1.103 xref: GO:0047644 xref: MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006947 name: alkan-1-ol dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor." [EC:1.1.99.20, MetaCyc:ALKAN-1-OL-DEHYDROGENASE-(ACCEPTOR)-RXN] synonym: "alkan-1-ol:(acceptor) oxidoreductase activity" EXACT [EC:1.1.99.20] synonym: "alkan-1-ol:acceptor oxidoreductase activity" EXACT [EC:1.1.99.20] synonym: "polyethylene glycol dehydrogenase activity" NARROW [EC:1.1.99.20] xref: EC:1.1.99.20 xref: GO:0047645 xref: MetaCyc:ALKAN-1-OL-DEHYDROGENASE-(ACCEPTOR)-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0006948 name: alkanal monooxygenase (FMN-linked) activity namespace: molecular_function def: "Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light." [EC:1.14.14.3, MetaCyc:ALKANAL-MONOOXYGENASE-(FMN-LINKED)-RXN] subset: gosubset_prok synonym: "aldehyde monooxygenase activity" BROAD [EC:1.14.14.3] synonym: "alkanal,reduced-FMN:oxygen oxidoreductase (1-hydroxylating, luminescing)" EXACT [EC:1.14.14.3] synonym: "bacterial luciferase activity" EXACT [EC:1.14.14.3] synonym: "vibrio fischeri luciferase activity" EXACT [EC:1.14.14.3] xref: EC:1.14.14.3 xref: GO:0047646 xref: MetaCyc:ALKANAL-MONOOXYGENASE-(FMN-LINKED)-RXN is_a: CCO:F0003295 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006949 name: alkylacetylglycerophosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycero-3-phosphate + H2O = 1-alkyl-2-acetyl-sn-glycerol + phosphate." [EC:3.1.3.59, MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN] synonym: "1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.59] synonym: "1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase activity" EXACT [EC:3.1.3.59] synonym: "alkylacetylglycerophosphate phosphatase activity" EXACT [EC:3.1.3.59] xref: EC:3.1.3.59 xref: GO:0047647 xref: MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0006950 name: alkylamidase activity namespace: molecular_function def: "Catalysis of the reaction: N-methylhexanamide + H2O = hexanoate + methylamine." [EC:3.5.1.39, MetaCyc:ALKYLAMIDASE-RXN] synonym: "N-methylhexanamide amidohydrolase activity" EXACT [EC:3.5.1.39] xref: EC:3.5.1.39 xref: GO:0047648 xref: MetaCyc:ALKYLAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006951 name: alkylglycerol kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-O-alkyl-sn-glycerol = ADP + 1-O-alkyl-sn-glycerol 3-phosphate." [EC:2.7.1.93, MetaCyc:ALKYLGLYCEROL-KINASE-RXN] synonym: "1-alkylglycerol kinase (phosphorylating)" EXACT [EC:2.7.1.93] synonym: "alkylglycerol phosphotransferase activity" EXACT [EC:2.7.1.93] synonym: "ATP-alkylglycerol phosphotransferase activity" EXACT [EC:2.7.1.93] synonym: "ATP:1-alkyl-sn-glycerol phosphotransferase activity" EXACT [EC:2.7.1.93] synonym: "ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase activity" EXACT [EC:2.7.1.93] xref: EC:2.7.1.93 xref: GO:0047649 xref: MetaCyc:ALKYLGLYCEROL-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006952 name: alkylglycerone kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + O-alkylglycerone = ADP + O-alkylglycerone phosphate." [EC:2.7.1.84, MetaCyc:ALKYLGLYCERONE-KINASE-RXN] synonym: "alkyldihydroxyacetone kinase (phosphorylating)" EXACT [EC:2.7.1.84] synonym: "alkyldihydroxyacetone kinase activity" EXACT [EC:2.7.1.84] synonym: "ATP:O-alkylglycerone phosphotransferase activity" EXACT [EC:2.7.1.84] xref: EC:2.7.1.84 xref: GO:0047650 xref: MetaCyc:ALKYLGLYCERONE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006953 name: alkylhalidase activity namespace: molecular_function def: "Catalysis of the reaction: bromochloromethane + H2O = formaldehyde + bromide + chloride." [EC:3.8.1.1, MetaCyc:ALKYLHALIDASE-RXN] subset: gosubset_prok synonym: "alkyl-halide halidohydrolase activity" EXACT [EC:3.8.1.1] synonym: "haloalkane halidohydrolase activity" EXACT [EC:3.8.1.1] synonym: "halogenase activity" RELATED [EC:3.8.1.1] xref: EC:3.8.1.1 xref: GO:0047651 xref: MetaCyc:ALKYLHALIDASE-RXN is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0006954 name: allantoate deiminase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2O + 2 allantoate = O2 + 2 CO2 + 2 NH3 + 2 ureidoglycine." [EC:3.5.3.9, MetaCyc:ALLANTOATE-DEIMINASE-RXN] synonym: "allantoate amidinohydrolase (decarboxylating)" EXACT [EC:3.5.3.9] synonym: "allantoate amidohydrolase activity" EXACT [EC:3.5.3.9] xref: EC:3.5.3.9 xref: GO:0047652 xref: MetaCyc:ALLANTOATE-DEIMINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0006955 name: allantoin racemase activity namespace: molecular_function def: "Catalysis of the reaction: (S)(+)-allantoin = (R)(-)-allantoin." [EC:5.1.99.3, MetaCyc:ALLANTOIN-RACEMASE-RXN] xref: EC:5.1.99.3 xref: GO:0047653 xref: MetaCyc:ALLANTOIN-RACEMASE-RXN is_a: CCO:F0003417 ! racemase and epimerase activity [Term] id: CCO:F0006956 name: alliin lyase activity namespace: molecular_function def: "Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate." [EC:4.4.1.4, MetaCyc:ALLIIN-LYASE-RXN] synonym: "alkylcysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] synonym: "alliin alkyl-sulfenate-lyase activity" EXACT [EC:4.4.1.4] synonym: "alliinase activity" EXACT [EC:4.4.1.4] synonym: "cysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] synonym: "cysteine sulphoxide lyase activity" EXACT [EC:4.4.1.4] synonym: "L-cysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] synonym: "S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-forming)" EXACT [EC:4.4.1.4] synonym: "S-alkylcysteine sulfoxide lyase activity" EXACT [EC:4.4.1.4] xref: EC:4.4.1.4 xref: GO:0047654 xref: MetaCyc:ALLIIN-LYASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0006957 name: allyl-alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: allyl alcohol + NADP+ = acrolein + NADPH." [EC:1.1.1.54, MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN] synonym: "allyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.54] xref: EC:1.1.1.54 xref: GO:0047655 xref: MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006958 name: alpha,alpha-trehalose phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate." [EC:2.4.1.64, MetaCyc:ALPHA] subset: gosubset_prok synonym: "a,a-trehalose phosphorylase activity" EXACT [] synonym: "alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.64] synonym: "trehalose phosphorylase" BROAD [EC:2.4.1.64] xref: EC:2.4.1.64 xref: GO:0047656 xref: MetaCyc:ALPHA is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0006959 name: alpha-1,3-glucan synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1." [EC:2.4.1.183, MetaCyc:ALPHA-1] synonym: "1,3-alpha-D-glucan synthase activity" EXACT [EC:2.4.1.183] synonym: "1,3-alpha-glucan synthase activity" EXACT [] synonym: "a-1,3-glucan synthase activity" EXACT [] synonym: "UDP-glucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] synonym: "UDPglucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] synonym: "uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase activity" EXACT [EC:2.4.1.183] xref: EC:2.4.1.183 xref: GO:0047657 xref: MetaCyc:ALPHA-1 is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006960 name: alpha-amino-acid esterase activity namespace: molecular_function def: "Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol." [EC:3.1.1.43, MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN] subset: gosubset_prok synonym: "a-amino-acid esterase activity" EXACT [] synonym: "alpha-amino acid ester hydrolase activity" EXACT [EC:3.1.1.43] synonym: "alpha-amino-acid ester hydrolase activity" EXACT [EC:3.1.1.43] synonym: "alpha-amino-acid-ester aminoacylhydrolase activity" EXACT [EC:3.1.1.43] xref: EC:3.1.1.43 xref: GO:0047658 xref: MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0006961 name: alpha-santonin 1,2-reductase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+." [EC:1.3.1.47, MetaCyc:ALPHA-SANTONIN-1] synonym: "1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase activity" EXACT [EC:1.3.1.47] synonym: "a-santonin 1,2-reductase activity" EXACT [] xref: EC:1.3.1.47 xref: GO:0047659 xref: MetaCyc:ALPHA-SANTONIN-1 is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006962 name: amidinoaspartase activity namespace: molecular_function def: "Catalysis of the reaction: N-amidino-L-aspartate + H2O = L-aspartate + urea." [EC:3.5.3.14, MetaCyc:AMIDINOASPARTASE-RXN] synonym: "amidinoaspartic amidinohydrolase activity" EXACT [EC:3.5.3.14] synonym: "N-amidino-L-aspartate amidinohydrolase activity" EXACT [EC:3.5.3.14] xref: EC:3.5.3.14 xref: GO:0047660 xref: MetaCyc:AMIDINOASPARTASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0006963 name: amino-acid racemase activity namespace: molecular_function def: "Catalysis of the reaction: an L-amino acid = a D-amino acid." [EC:5.1.1.10, MetaCyc:AMINO-ACID-RACEMASE-RXN] subset: gosubset_prok synonym: "L-amino acid racemase activity" EXACT [EC:5.1.1.10] xref: EC:5.1.1.10 xref: GO:0047661 xref: MetaCyc:AMINO-ACID-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0006964 name: aminobenzoate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2." [EC:4.1.1.24, MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN] synonym: "aminobenzoate carboxy-lyase (aniline-forming)" EXACT [EC:4.1.1.24] synonym: "aminobenzoate carboxy-lyase activity" EXACT [EC:4.1.1.24] xref: EC:4.1.1.24 xref: GO:0047662 xref: MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006965 name: aminoglycoside 6'-N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 6'-N-acetylaminoglycoside. This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring." [GOC:cb] subset: gosubset_prok synonym: "6'-aminoglycoside-N-acetyltransferase activity" EXACT [EC:2.3.1.82] synonym: "AAC(6') activity" RELATED [EC:2.3.1.82] synonym: "acetyl-CoA:kanamycin-B N6'-acetyltransferase activity" NARROW [EC:2.3.1.82] synonym: "aminoglycoside N6'-acetyltransferase activity" EXACT [] synonym: "aminoglycoside-6'-acetyltransferase activity" EXACT [EC:2.3.1.82] synonym: "aminoglycoside-6-N-acetyltransferase activity" EXACT [EC:2.3.1.82] synonym: "kanamycin 6'-N-acetyltransferase activity" NARROW [] xref: EC:2.3.1.82 xref: GO:0047663 xref: MetaCyc:AMINOGLYCOSIDE-N6 is_a: CCO:F0005513 ! aminoglycoside N-acetyltransferase activity [Term] id: CCO:F0006966 name: aminoimidazolase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminoimidazole + H2O = unidentified product + NH3." [EC:3.5.4.8, MetaCyc:AMINOIMIDAZOLASE-RXN] synonym: "4-aminoimidazole aminohydrolase activity" EXACT [EC:3.5.4.8] synonym: "4-aminoimidazole hydrolase activity" EXACT [EC:3.5.4.8] xref: EC:3.5.4.8 xref: GO:0047664 xref: MetaCyc:AMINOIMIDAZOLASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [Term] id: CCO:F0006967 name: aminolevulinate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine." [EC:2.6.1.43, MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN] synonym: "4,5-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "4,5-dioxovaleric acid aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "4,5-dioxovaleric acid transaminase activity" EXACT [EC:2.6.1.43] synonym: "4,5-dioxovaleric transaminase activity" EXACT [EC:2.6.1.43] synonym: "5-aminolevulinate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "5-aminolevulinic acid transaminase activity" EXACT [EC:2.6.1.43] synonym: "alanine-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "alanine-gamma,delta-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "alanine:4,5-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "aminolevulinate aminotransferase activity" EXACT [] synonym: "aminolevulinic acid transaminase activity" EXACT [EC:2.6.1.43] synonym: "dioxovalerate transaminase activity" EXACT [EC:2.6.1.43] synonym: "DOVA transaminase activity" EXACT [EC:2.6.1.43] synonym: "gamma,delta-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "gamma,delta-dioxovaleric acid transaminase activity" EXACT [EC:2.6.1.43] synonym: "L-alanine-4,5-dioxovalerate aminotransferase activity" EXACT [EC:2.6.1.43] synonym: "L-alanine:4,5-dioxovaleric acid transaminase activity" EXACT [EC:2.6.1.43] synonym: "L-alanine:dioxovalerate transaminase activity" EXACT [EC:2.6.1.43] xref: EC:2.6.1.43 xref: GO:0047665 xref: MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0006968 name: ammonia kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + NH3 = ADP + phosphoramide." [EC:2.7.3.8, MetaCyc:AMMONIA-KINASE-RXN] synonym: "ATP:ammonia phosphotransferase activity" EXACT [EC:2.7.3.8] synonym: "phosphoramidate-adenosine diphosphate phosphotransferase activity" EXACT [EC:2.7.3.8] synonym: "phosphoramidate-ADP-phosphotransferase activity" EXACT [EC:2.7.3.8] xref: EC:2.7.3.8 xref: GO:0047666 xref: MetaCyc:AMMONIA-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0006969 name: AMP-thymidine kinase activity namespace: molecular_function def: "Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate." [EC:2.7.1.114, MetaCyc:AMP--THYMIDINE-KINASE-RXN] synonym: "adenylate-nucleoside phosphotransferase activity" EXACT [EC:2.7.1.114] synonym: "adenylic acid:deoxythymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.114] synonym: "AMP:deoxythymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.114] synonym: "AMP:deoxythymidine kinase activity" EXACT [EC:2.7.1.114] synonym: "AMP:dThd kinase activity" EXACT [EC:2.7.1.114] synonym: "AMP:thymidine 5'-phosphotransferase activity" EXACT [EC:2.7.1.114] synonym: "thymidine phosphotransferase activity" EXACT [EC:2.7.1.114] xref: EC:2.7.1.114 xref: GO:0047667 xref: MetaCyc:AMP--THYMIDINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0006970 name: amygdalin beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-amygdalin + H2O = (R)-prunasin + D-glucose." [EC:3.2.1.117, MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN] synonym: "amygdalin b-glucosidase activity" EXACT [] synonym: "amygdalin beta-D-glucohydrolase activity" EXACT [EC:3.2.1.117] synonym: "amygdalin glucosidase activity" EXACT [EC:3.2.1.117] synonym: "amygdalin hydrolase activity" EXACT [EC:3.2.1.117] synonym: "amygdalinase" BROAD [EC:3.2.1.117] xref: EC:3.2.1.117 xref: GO:0047668 xref: MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0006971 name: amylosucrase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1)." [EC:2.4.1.4, MetaCyc:AMYLOSUCRASE-RXN] subset: gosubset_prok synonym: "sucrose-1,4-alpha-glucan glucosyltransferase activity" EXACT [EC:2.4.1.4] synonym: "sucrose-glucan glucosyltransferase activity" EXACT [EC:2.4.1.4] synonym: "sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.4] xref: EC:2.4.1.4 xref: GO:0047669 xref: MetaCyc:AMYLOSUCRASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0006972 name: anhydrotetracycline monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: anhydrotetracycline + NADPH + O2 = 12-dehydrotetracycline + NADP+ + H2O." [EC:1.14.13.38, MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN] synonym: "anhydrotetracycline oxygenase activity" EXACT [EC:1.14.13.38] synonym: "anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.38] synonym: "ATC oxygenase activity" EXACT [EC:1.14.13.38] xref: EC:1.14.13.38 xref: GO:0047670 xref: MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0006973 name: anthranilate adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + anthranilate = diphosphate + N-adenylylanthranilate." [EC:2.7.7.55, MetaCyc:ANTHRANILATE-ADENYLYLTRANSFERASE-RXN] synonym: "anthranilic acid adenylyltransferase activity" EXACT [EC:2.7.7.55] synonym: "ATP:anthranilate adenylyltransferase activity" EXACT [] synonym: "ATP:anthranilate N-adenylyltransferase activity" EXACT [EC:2.7.7.55] xref: EC:2.7.7.55 xref: GO:0047671 xref: MetaCyc:ANTHRANILATE-ADENYLYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0006974 name: anthranilate N-benzoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: benzoyl-CoA + anthranilate = CoA + N-benzoylanthranilate." [EC:2.3.1.144, MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN] synonym: "benzoyl-CoA:anthranilate N-benzoyltransferase" BROAD [EC:2.3.1.144] xref: EC:2.3.1.144 xref: GO:0047672 xref: MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0006975 name: anthranilate N-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: malonyl-CoA + anthranilate = CoA + N-malonylanthranilate." [EC:2.3.1.113, MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN] synonym: "malonyl-CoA:anthranilate N-malonyltransferase activity" EXACT [EC:2.3.1.113] xref: EC:2.3.1.113 xref: GO:0047673 xref: MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN is_a: CCO:F0008003 ! N-malonyltransferase activity [Term] id: CCO:F0006976 name: apiose 1-reductase activity namespace: molecular_function def: "Catalysis of the reaction: D-apiitol + NAD+ = D-apiose + NADH." [EC:1.1.1.114, MetaCyc:APIOSE-1-REDUCTASE-RXN] synonym: "D-apiitol reductase activity" EXACT [EC:1.1.1.114] synonym: "D-apiitol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.114] synonym: "D-apiose reductase activity" EXACT [EC:1.1.1.114] xref: EC:1.1.1.114 xref: GO:0047674 xref: MetaCyc:APIOSE-1-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006977 name: arabinonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H2O." [EC:4.2.1.5, MetaCyc:ARABINONATE-DEHYDRATASE-RXN] synonym: "D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)" EXACT [EC:4.2.1.5] synonym: "D-arabinonate hydro-lyase activity" EXACT [EC:4.2.1.5] xref: EC:4.2.1.5 xref: GO:0047675 xref: MetaCyc:ARABINONATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0006978 name: arachidonate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA." [EC:6.2.1.15, MetaCyc:ARACHIDONATE--COA-LIGASE-RXN] synonym: "arachidonate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.15] synonym: "arachidonoyl-CoA synthetase activity" EXACT [EC:6.2.1.15] xref: EC:6.2.1.15 xref: GO:0047676 xref: MetaCyc:ARACHIDONATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0006979 name: arachidonate 8-lipoxygenase activity namespace: molecular_function def: "Catalysis of the reaction: arachidonate + O2 = (5Z,9E,11Z,14Z)-(8R)-8-hydroperoxyicosa-5,9,11,14-tetraenoate." [EC:1.13.11.40, MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN] synonym: "8(R)-lipoxygenase activity" EXACT [EC:1.13.11.40] synonym: "8-lipoxygenase activity" NARROW [EC:1.13.11.40] synonym: "arachidonate:oxygen 8-oxidoreductase activity" EXACT [EC:1.13.11.40] xref: EC:1.13.11.40 xref: GO:0047677 xref: MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006980 name: arginine 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O." [EC:1.13.12.1, MetaCyc:ARGININE-2-MONOOXYGENASE-RXN] synonym: "arginine decarboxy-oxidase activity" EXACT [EC:1.13.12.1] synonym: "arginine monooxygenase activity" EXACT [EC:1.13.12.1] synonym: "arginine oxygenase (decarboxylating) activity" EXACT [EC:1.13.12.1] synonym: "L-arginine:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.1] xref: EC:1.13.12.1 xref: GO:0047678 xref: MetaCyc:ARGININE-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) [Term] id: CCO:F0006981 name: arginine racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-arginine = D-arginine." [EC:5.1.1.9, MetaCyc:ARGININE-RACEMASE-RXN] xref: EC:5.1.1.9 xref: GO:0047679 xref: MetaCyc:ARGININE-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0006982 name: aryl-acylamidase activity namespace: molecular_function def: "Catalysis of the reaction: an anilide + H2O = a carboxylate + aniline." [EC:3.5.1.13, MetaCyc:ARYL-ACYLAMIDASE-RXN] subset: gosubset_prok synonym: "AAA-1" RELATED [EC:3.5.1.13] synonym: "AAA-2" RELATED [EC:3.5.1.13] synonym: "aryl-acylamide amidohydrolase activity" EXACT [EC:3.5.1.13] synonym: "brain acetylcholinesterase (is associated with AAA-2)" EXACT [EC:3.5.1.13] synonym: "pseudocholinesterase (associated with arylacylamidase)" EXACT [EC:3.5.1.13] xref: EC:3.5.1.13 xref: GO:0047680 xref: MetaCyc:ARYL-ACYLAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0006983 name: aryl-alcohol dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH." [EC:1.1.1.91, MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-(NADP+)-RXN] synonym: "aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate)" EXACT [EC:1.1.1.91] synonym: "aryl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.91] synonym: "coniferyl alcohol dehydrogenase" BROAD [EC:1.1.1.91] synonym: "NADPH-linked benzaldehyde reductase activity" EXACT [EC:1.1.1.91] xref: EC:1.1.1.91 xref: GO:0047681 xref: MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006984 name: aryl-alcohol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2." [EC:1.1.3.7, MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN] synonym: "arom. alcohol oxidase activity" EXACT [EC:1.1.3.7] synonym: "aryl alcohol oxidase activity" EXACT [EC:1.1.3.7] synonym: "aryl-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.7] synonym: "veratryl alcohol oxidase activity" NARROW [EC:1.1.3.7] xref: EC:1.1.3.7 xref: GO:0047682 xref: MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0006985 name: aryl-aldehyde dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP." [EC:1.2.1.30, MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-(NADP+)-RXN] synonym: "aromatic acid reductase activity" EXACT [EC:1.2.1.30] synonym: "aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)" EXACT [EC:1.2.1.30] xref: EC:1.2.1.30 xref: GO:0047683 xref: MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0006986 name: arylamine glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine." [EC:2.4.1.71, MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN] synonym: "UDP glucose-arylamine glucosyltransferase activity" EXACT [EC:2.4.1.71] synonym: "UDP-glucose:arylamine N-D-glucosyltransferase activity" EXACT [EC:2.4.1.71] synonym: "UDPglucose:arylamine N-D-glucosyltransferase activity" EXACT [EC:2.4.1.71] synonym: "uridine diphosphoglucose-arylamine glucosyltransferase activity" EXACT [EC:2.4.1.71] xref: EC:2.4.1.71 xref: GO:0047684 xref: MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0006987 name: amine sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate." [EC:2.8.2.3, MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:amine N-sulfotransferase activity" EXACT [EC:2.8.2.3] synonym: "amine N-sulfotransferase activity" EXACT [EC:2.8.2.3] synonym: "amine sulphotransferase activity" EXACT [] synonym: "arylamine sulfotransferase activity" EXACT [] xref: EC:2.8.2.3 xref: GO:0047685 xref: MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006988 name: arylsulfate sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate." [EC:2.8.2.22, MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN] subset: gosubset_prok synonym: "arylsulfate-phenol sulfotransferase activity" EXACT [EC:2.8.2.22] synonym: "arylsulfate:phenol sulfotransferase activity" EXACT [EC:2.8.2.22] synonym: "arylsulfotransferase" BROAD [EC:2.8.2.22] synonym: "arylsulphate sulphotransferase activity" EXACT [] synonym: "ASST" RELATED [EC:2.8.2.22] xref: EC:2.8.2.22 xref: GO:0047686 xref: MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0006989 name: ascorbate 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + O2 + ascorbate = L-threonate + oxalate." [EC:1.13.11.13, MetaCyc:ASCORBATE-2] synonym: "AAoxygenase activity" EXACT [EC:1.13.11.13] synonym: "ascorbate:oxygen 2,3-oxidoreductase (bond-cleaving)" EXACT [EC:1.13.11.13] xref: EC:1.13.11.13 xref: GO:0047687 xref: MetaCyc:ASCORBATE-2 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0006990 name: aspartate 4-decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate = L-alanine + CO2." [EC:4.1.1.12, MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN] subset: gosubset_prok synonym: "aminomalonic decarboxylase activity" EXACT [EC:4.1.1.12] synonym: "aspartate beta-decarboxylase activity" EXACT [EC:4.1.1.12] synonym: "aspartate omega-decarboxylase activity" EXACT [EC:4.1.1.12] synonym: "aspartic beta-decarboxylase activity" EXACT [EC:4.1.1.12] synonym: "aspartic omega-decarboxylase activity" EXACT [EC:4.1.1.12] synonym: "cysteine sulfinic desulfinase activity" EXACT [EC:4.1.1.12] synonym: "desulfinase activity" EXACT [EC:4.1.1.12] synonym: "L-aspartate 4-carboxy-lyase (L-alanine-forming)" EXACT [EC:4.1.1.12] synonym: "L-aspartate 4-carboxy-lyase activity" EXACT [EC:4.1.1.12] synonym: "L-aspartate beta-decarboxylase activity" EXACT [EC:4.1.1.12] synonym: "L-cysteine sulfinate acid desulfinase activity" EXACT [EC:4.1.1.12] xref: EC:4.1.1.12 xref: GO:0047688 xref: MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0006991 name: aspartate racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-aspartate = D-aspartate." [EC:5.1.1.13, MetaCyc:ASPARTATE-RACEMASE-RXN] subset: gosubset_prok synonym: "D-aspartate racemase activity" EXACT [EC:5.1.1.13] xref: EC:5.1.1.13 xref: GO:0047689 xref: MetaCyc:ASPARTATE-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0006992 name: aspartyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-asparagine + hydroxylamine = NH3 + L-aspartylhydroxamate." [EC:2.3.2.7, MetaCyc:ASPARTYLTRANSFERASE-RXN] synonym: "aspartotransferase activity" EXACT [EC:2.3.2.7] synonym: "beta-aspartyl transferase activity" EXACT [EC:2.3.2.7] synonym: "L-asparagine:hydroxylamine gamma-aspartyltransferase activity" EXACT [EC:2.3.2.7] xref: EC:2.3.2.7 xref: GO:0047690 xref: MetaCyc:ASPARTYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0006993 name: aspulvinone dimethylallyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 dimethylallyl diphosphate + aspulvinone E = 2 diphosphate + aspulvinone H." [EC:2.5.1.35, MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN] synonym: "dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase activity" EXACT [EC:2.5.1.35] synonym: "dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase activity" EXACT [EC:2.5.1.35] xref: EC:2.5.1.35 xref: GO:0047691 xref: MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0006994 name: ATP deaminase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ITP + NH3." [EC:3.5.4.18, MetaCyc:ATP-DEAMINASE-RXN] synonym: "adenosine triphosphate deaminase activity" EXACT [EC:3.5.4.18] synonym: "ATP aminohydrolase activity" EXACT [EC:3.5.4.18] xref: EC:3.5.4.18 xref: GO:0047692 xref: MetaCyc:ATP-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0006995 name: ATP diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = AMP + diphosphate." [EC:3.6.1.8, MetaCyc:ATP-PYROPHOSPHATASE-RXN] subset: gosubset_prok synonym: "adenosine triphosphate pyrophosphatase activity" EXACT [EC:3.6.1.8] synonym: "ATP diphosphohydrolase" BROAD [EC:3.6.1.8] synonym: "ATP diphosphohydrolase (diphosphate-forming)" EXACT [EC:3.6.1.8] synonym: "ATP pyrophosphatase activity" EXACT [] xref: EC:3.6.1.8 xref: GO:0047693 xref: MetaCyc:ATP-PYROPHOSPHATASE-RXN is_a: CCO:F0006737 ! nucleoside-triphosphate diphosphatase activity [Term] id: CCO:F0006996 name: barbiturase activity namespace: molecular_function def: "Catalysis of the reaction: barbiturate + H2O = malonate + urea." [EC:3.5.2.1, MetaCyc:BARBITURASE-RXN] synonym: "barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming)" EXACT [EC:3.5.2.1] xref: EC:3.5.2.1 xref: GO:0047694 xref: MetaCyc:BARBITURASE-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0006997 name: benzoin aldolase activity namespace: molecular_function def: "Catalysis of the reaction: benzoin = 2 benzaldehyde." [EC:4.1.2.38, MetaCyc:BENZOIN-ALDOLASE-RXN] subset: gosubset_prok synonym: "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2- activity" EXACT [EC:4.1.2.38] synonym: "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)" EXACT [EC:4.1.2.38] synonym: "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase activity" EXACT [EC:4.1.2.38] synonym: "benzaldehyde lyase activity" EXACT [EC:4.1.2.38] synonym: "diphenylethanone benzaldehyde-lyase activity" EXACT [EC:4.1.2.38] xref: EC:4.1.2.38 xref: GO:0047695 xref: MetaCyc:BENZOIN-ALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0006998 name: beta-adrenergic receptor kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor." [EC:2.7.11.15, MetaCyc:BETA-ADRENERGIC-RECEPTOR-KINASE-RXN] synonym: "[b-adrenergic-receptor] kinase activity" EXACT [EC:2.7.11.15] synonym: "ADRBK1" RELATED [EC:2.7.11.15] synonym: "adrenergic receptor kinase activity" BROAD [EC:2.7.11.15] synonym: "ATP:beta-adrenergic-receptor phosphotransferase activity" BROAD [EC:2.7.11.15] synonym: "BARK1" RELATED [EC:2.7.11.15] synonym: "beta-adrenergic receptor-specific kinase activity" EXACT [EC:2.7.11.15] synonym: "beta-adrenergic-receptor kinase (phosphorylating) activity" EXACT [EC:2.7.11.15] synonym: "beta-adrenergic-receptor kinase activity" EXACT [EC:2.7.11.15] synonym: "beta-adrenoceptor kinase 1 activity" NARROW [EC:2.7.11.15] synonym: "beta-adrenoceptor kinase 2 activity" NARROW [EC:2.7.11.15] synonym: "beta-adrenoceptor kinase activity" EXACT [EC:2.7.11.15] synonym: "beta-AR kinase activity" EXACT [EC:2.7.11.15] synonym: "beta-ARK" RELATED [EC:2.7.11.15] synonym: "beta-ARK 1" RELATED [EC:2.7.11.15] synonym: "beta-ARK 2" RELATED [EC:2.7.11.15] synonym: "beta-receptor kinase activity" EXACT [EC:2.7.11.15] synonym: "beta2ARK" RELATED [EC:2.7.11.15] synonym: "betaARK1" RELATED [EC:2.7.11.15] synonym: "GRK2" RELATED [EC:2.7.11.15] synonym: "GRK3" RELATED [EC:2.7.11.15] synonym: "STK15" RELATED [EC:2.7.11.15] xref: EC:2.7.11.15 xref: GO:0047696 xref: MetaCyc:BETA-ADRENERGIC-RECEPTOR-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0006999 name: beta-alanopine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: beta-alanopine + NAD+ + H2O = beta-alanine + pyruvate + NADH." [EC:1.5.1.26, MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN] synonym: "b-alanopine dehydrogenase activity" EXACT [] synonym: "N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming)" EXACT [EC:1.5.1.26] xref: EC:1.5.1.26 xref: GO:0047697 xref: MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007000 name: beta-alanyl-CoA ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3." [EC:4.3.1.6, MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN] synonym: "b-alanyl-CoA ammonia-lyase activity" EXACT [] synonym: "beta-alanyl coenzyme A ammonia-lyase activity" EXACT [EC:4.3.1.6] synonym: "beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming)" EXACT [EC:4.3.1.6] xref: EC:4.3.1.6 xref: GO:0047698 xref: MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0007001 name: beta-diketone hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: nonane-4,6-dione + H2O = pentan-2-one + butanoate." [EC:3.7.1.7, MetaCyc:BETA-DIKETONE-HYDROLASE-RXN] synonym: "b-diketone hydrolase activity" EXACT [] synonym: "nonane-4,6-dione acylhydrolase activity" EXACT [EC:3.7.1.7] synonym: "oxidized PVA hydrolase activity" EXACT [EC:3.7.1.7] xref: EC:3.7.1.7 xref: GO:0047699 xref: MetaCyc:BETA-DIKETONE-HYDROLASE-RXN is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0007002 name: beta-glucoside kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose." [EC:2.7.1.85, MetaCyc:BETA-GLUCOSIDE-KINASE-RXN] subset: gosubset_prok synonym: "ATP:cellobiose 6-phosphotransferase activity" EXACT [EC:2.7.1.85] synonym: "b-glucoside kinase activity" EXACT [] synonym: "beta-D-glucoside kinase (phosphorylating)" EXACT [EC:2.7.1.85] xref: EC:2.7.1.85 xref: GO:0047700 xref: MetaCyc:BETA-GLUCOSIDE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007003 name: beta-L-arabinosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol." [EC:3.2.1.88, MetaCyc:BETA-L-ARABINOSIDASE-RXN] synonym: "b-L-arabinosidase activity" EXACT [] synonym: "beta-L-arabinoside arabinohydrolase activity" EXACT [EC:3.2.1.88] synonym: "vicianosidase activity" EXACT [EC:3.2.1.88] xref: EC:3.2.1.88 xref: GO:0047701 xref: MetaCyc:BETA-L-ARABINOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007004 name: beta-lysine 5,6-aminomutase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate." [EC:5.4.3.3, MetaCyc:BETA-LYSINE-5] subset: gosubset_prok synonym: "(3S)-3,6-diaminohexanoate 5,6-aminomutase activity" EXACT [EC:5.4.3.3] synonym: "b-lysine 5,6-aminomutase activity" EXACT [] synonym: "beta-lysine mutase activity" EXACT [EC:5.4.3.3] synonym: "L-beta-lysine 5,6-aminomutase activity" EXACT [EC:5.4.3.3] xref: EC:5.4.3.3 xref: GO:0047702 xref: MetaCyc:BETA-LYSINE-5 is_a: CCO:F0003430 ! intramolecular transferase activity, transferring amino groups [Term] id: CCO:F0007005 name: beta-nitroacrylate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-nitropropanoate + NADP+ = 3-nitroacrylate + NADPH." [EC:1.3.1.16, MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN] synonym: "3-nitropropanoate:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.16] synonym: "b-nitroacrylate reductase activity" EXACT [] xref: EC:1.3.1.16 xref: GO:0047703 xref: MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007006 name: bile-salt sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate." [EC:2.8.2.14, MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase activity" EXACT [EC:2.8.2.14] synonym: "BAST I activity" NARROW [EC:2.8.2.14] synonym: "bile acid sulfotransferase I activity" NARROW [EC:2.8.2.14] synonym: "bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity" EXACT [EC:2.8.2.14] synonym: "bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase activity" EXACT [EC:2.8.2.14] synonym: "bile-salt sulphotransferase activity" EXACT [] synonym: "glycolithocholate sulfotransferase activity" NARROW [EC:2.8.2.14] xref: EC:2.8.2.14 xref: GO:0047704 xref: MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007007 name: bilirubin oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 bilirubin + O2 = 2 biliverdin + 2 H2O." [EC:1.3.3.5, MetaCyc:BILIRUBIN-OXIDASE-RXN] synonym: "bilirubin oxidase M-1" RELATED [EC:1.3.3.5] synonym: "bilirubin:oxygen oxidoreductase activity" EXACT [EC:1.3.3.5] xref: EC:1.3.3.5 xref: GO:0047705 xref: MetaCyc:BILIRUBIN-OXIDASE-RXN is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0007008 name: biochanin-A reductase activity namespace: molecular_function def: "Catalysis of the reaction: dihydrobiochanin A + NADP+ = biochanin A + NADPH." [EC:1.3.1.46, MetaCyc:BIOCHANIN-A-REDUCTASE-RXN] synonym: "dihydrobiochanin-A:NADP+ delta2-oxidoreductase activity" EXACT [EC:1.3.1.46] xref: EC:1.3.1.46 xref: GO:0047706 xref: MetaCyc:BIOCHANIN-A-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007009 name: biotin-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA." [EC:6.2.1.11, MetaCyc:BIOTIN--COA-LIGASE-RXN] synonym: "biotin CoA synthetase activity" EXACT [EC:6.2.1.11] synonym: "biotin:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.11] synonym: "biotinyl coenzyme A synthetase activity" EXACT [EC:6.2.1.11] synonym: "biotinyl-CoA synthetase activity" EXACT [EC:6.2.1.11] xref: EC:6.2.1.11 xref: GO:0047707 xref: MetaCyc:BIOTIN--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007010 name: biotinidase activity namespace: molecular_function def: "Catalysis of the reaction: biotin amide + H2O = biotin + NH3." [EC:3.5.1.12, MetaCyc:BIOTINIDASE-RXN] synonym: "amidohydrolase biotinidase activity" EXACT [EC:3.5.1.12] synonym: "biotin-amide amidohydrolase activity" EXACT [EC:3.5.1.12] xref: EC:3.5.1.12 xref: GO:0047708 xref: MetaCyc:BIOTINIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007011 name: bis(2-ethylhexyl)phthalate esterase activity namespace: molecular_function def: "Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexyl phthalate + 2-ethylhexan-1-ol." [EC:3.1.1.60, MetaCyc:BIS(2-ETHYLHEXYL)PHTHALATE-ESTERASE-RXN] synonym: "bis(2-ethylhexyl)phthalate acylhydrolase activity" EXACT [EC:3.1.1.60] synonym: "DEHP esterase activity" EXACT [EC:3.1.1.60] xref: EC:3.1.1.60 xref: GO:0047709 xref: MetaCyc:BIS(2-ETHYLHEXYL)PHTHALATE-ESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007012 name: bis(5'-adenosyl)-triphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: P1-P3-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP." [EC:3.6.1.29, MetaCyc:BIS(5] synonym: "1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase activity" EXACT [EC:3.6.1.29] synonym: "AP(3)A hydrolase activity" EXACT [EC:3.6.1.29] synonym: "AP(3)Aase activity" EXACT [EC:3.6.1.29] synonym: "AP3A hydrolase activity" EXACT [EC:3.6.1.29] synonym: "AP3Aase activity" EXACT [EC:3.6.1.29] synonym: "diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase activity" EXACT [EC:3.6.1.29] synonym: "diadenosine 5',5'''-P1,P3-triphosphate hydrolase activity" EXACT [EC:3.6.1.29] synonym: "diadenosine 5,5-P1,P3-triphosphatase activity" EXACT [EC:3.6.1.29] synonym: "dinucleosidetriphosphatase activity" EXACT [EC:3.6.1.29] synonym: "P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase activity" EXACT [EC:3.6.1.29] xref: EC:3.6.1.29 xref: GO:0047710 xref: MetaCyc:BIS(5 is_a: CCO:F0000937 ! nucleotide diphosphatase activity [Term] id: CCO:F0007013 name: blasticidin-S deaminase activity namespace: molecular_function def: "Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3." [EC:3.5.4.23, MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN] subset: gosubset_prok synonym: "blasticidin-S aminohydrolase activity" EXACT [EC:3.5.4.23] xref: EC:3.5.4.23 xref: GO:0047711 xref: MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007014 name: Cypridina-luciferin 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light." [EC:1.13.12.6, MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN] synonym: "Cypridina luciferase activity" EXACT [EC:1.13.12.6] synonym: "Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.6] synonym: "Cypridina-type luciferase activity" EXACT [EC:1.13.12.6] synonym: "cypridina-type luciferase activity" EXACT [EC:1.13.12.6] synonym: "luciferase (Cypridina luciferin)" EXACT [EC:1.13.12.6] synonym: "luciferase activity" BROAD [EC:1.13.12.6] xref: EC:1.13.12.6 xref: GO:0047712 xref: MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) is_a: CCO:F0006100 ! luciferin monooxygenase activity [Term] id: CCO:F0007015 name: galactitol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: galactitol + NAD+ = D-tagatose + NADH." [EC:1.1.1.16, MetaCyc:GALACTITOL-2-DEHYDROGENASE-RXN] xref: EC:1.1.1.16 xref: GO:0047713 xref: MetaCyc:GALACTITOL-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor is_a: CCO:F0004651 ! hexitol dehydrogenase activity [Term] id: CCO:F0007016 name: galactolipase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates." [EC:3.1.1.26, MetaCyc:GALACTOLIPASE-RXN] synonym: "1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity" EXACT [EC:3.1.1.26] synonym: "galactolipid acylhydrolase activity" EXACT [EC:3.1.1.26] synonym: "galactolipid lipase activity" EXACT [EC:3.1.1.26] synonym: "polygalactolipase activity" EXACT [EC:3.1.1.26] xref: EC:3.1.1.26 xref: GO:0047714 xref: MetaCyc:GALACTOLIPASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0003111 ! lipase activity [Term] id: CCO:F0007017 name: hypotaurocyamine kinase activity namespace: molecular_function def: "Catalysis of the reaction: hypotaurocyamine + ATP = N(omega)-phosphohypotaurocyamine + ADP." [EC:2.7.3.6, MetaCyc:HYPOTAUROCYAMINE-KINASE-RXN] synonym: "ATP:hypotaurocyamine N-phosphotransferase activity" EXACT [EC:2.7.3.6] xref: EC:2.7.3.6 xref: GO:0047715 xref: MetaCyc:HYPOTAUROCYAMINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0007018 name: imidazole N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + imidazole = CoA + N-acetylimidazole." [EC:2.3.1.2, MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:imidazole N-acetyltransferase activity" EXACT [EC:2.3.1.2] synonym: "imidazole acetylase activity" EXACT [EC:2.3.1.2] synonym: "imidazole acetyltransferase activity" EXACT [EC:2.3.1.2] xref: EC:2.3.1.2 xref: GO:0047716 xref: MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0007019 name: imidazoleacetate 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-imidazoleacetate + NADH + O2 = 5-hydroxy-4-imidazoleacetate + NAD+ + H2O." [EC:1.14.13.5, MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN] synonym: "4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)" EXACT [EC:1.14.13.5] synonym: "imidazoleacetate hydroxylase activity" EXACT [EC:1.14.13.5] synonym: "imidazoleacetic hydroxylase activity" EXACT [] synonym: "imidazoleacetic monooxygenase activity" EXACT [EC:1.14.13.5] xref: EC:1.14.13.5 xref: GO:0047717 xref: MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007020 name: indanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+." [EC:1.1.1.112, MetaCyc:INDANOL-DEHYDROGENASE-RXN] synonym: "indan-1-ol:NAD(P)+ 1-oxidoreductase activity" EXACT [EC:1.1.1.112] xref: EC:1.1.1.112 xref: GO:0047718 xref: MetaCyc:INDANOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007021 name: indole 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: indole + O2 = 2-formylaminobenzaldehyde." [EC:1.13.11.17, MetaCyc:INDOLE-2] synonym: "IDO" RELATED [EC:1.13.11.17] synonym: "indole oxidase activity" EXACT [EC:1.13.11.17] synonym: "indole-oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.17] synonym: "indole:O2 oxidoreductase activity" EXACT [EC:1.13.11.17] synonym: "indole:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.17] xref: EC:1.13.11.17 xref: GO:0047719 xref: MetaCyc:INDOLE-2 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007022 name: indoleacetaldoxime dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: indole-3-acetaldoxime = indole-3-acetonitrile + H2O." [EC:4.2.1.29, MetaCyc:INDOLEACETALDOXIME-DEHYDRATASE-RXN] synonym: "(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]" RELATED [EC:4.99.1.6] synonym: "(indol-3-yl)acetaldehyde-oxime hydro-lyase activity" EXACT [EC:4.99.1.6] synonym: "3-indoleacetaldoxime hydro-lyase activity" EXACT [EC:4.99.1.6] synonym: "indole-3-acetaldehyde-oxime hydro-lyase activity" EXACT [EC:4.99.1.6] synonym: "indole-3-acetaldoxime hydro-lyase activity" EXACT [EC:4.99.1.6] synonym: "indoleacetaldoxime hydro-lyase activity" EXACT [EC:4.99.1.6] xref: EC:4.99.1.6 xref: GO:0047720 xref: MetaCyc:RXN-1403 is_a: CCO:F0003396 ! lyase activity [Term] id: CCO:F0007023 name: indoleacetate-lysine synthetase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + indoleacetate + L-lysine = ADP + phosphate + N6-[(indole-3-yl)acetyl]-L-lysine." [EC:6.3.2.20, MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN] subset: gosubset_prok synonym: "(indol-3-yl)acetate:L-lysine ligase (ADP-forming)" EXACT [EC:6.3.2.20] synonym: "IAA-lysine synthetase activity" EXACT [EC:6.3.2.20] synonym: "indoleacetate-lysine ligase activity" EXACT [] synonym: "indoleacetate:L-lysine ligase (ADP-forming)" EXACT [EC:6.3.2.20] synonym: "N-(indole-3-acetyl)-L-lysine synthetase activity" EXACT [EC:6.3.2.20] xref: EC:6.3.2.20 xref: GO:0047721 xref: MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0007024 name: indolelactate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: indolelactate + NAD+ = indolepyruvate + NADH." [EC:1.1.1.110, MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN] synonym: "(indol-3-yl)lactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.110] synonym: "indole-3-lactate dehydrogenase activity" EXACT [] synonym: "indolelactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.110] xref: EC:1.1.1.110 xref: GO:0047722 xref: MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007025 name: inosinate nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-inosinate + H2O = D-ribose 5-phosphate + hypoxanthine." [EC:3.2.2.12, MetaCyc:INOSINATE-NUCLEOSIDASE-RXN] synonym: "5'-inosinate phosphoribohydrolase activity" EXACT [EC:3.2.2.12] xref: EC:3.2.2.12 xref: GO:0047723 xref: MetaCyc:INOSINATE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0007026 name: inosine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine." [EC:3.2.2.2, MetaCyc:INOSINE-NUCLEOSIDASE-RXN] synonym: "inosinase activity" EXACT [EC:3.2.2.2] synonym: "inosine ribohydrolase activity" EXACT [EC:3.2.2.2] synonym: "inosine-guanosine nucleosidase activity" EXACT [EC:3.2.2.2] xref: EC:3.2.2.2 xref: GO:0047724 xref: MetaCyc:INOSINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0007027 name: inulosucrase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1)." [EC:2.4.1.9, MetaCyc:INULOSUCRASE-RXN] subset: gosubset_prok synonym: "sucrose 1-fructosyl transferase activity" EXACT [EC:2.4.1.9] synonym: "sucrose 1-fructosyltransferase activity" EXACT [EC:2.4.1.9] synonym: "sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.9] xref: EC:2.4.1.9 xref: GO:0047725 xref: MetaCyc:INULOSUCRASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007028 name: iron-cytochrome-c reductase activity namespace: molecular_function def: "Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+." [EC:1.9.99.1, MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN] synonym: "ferrocytochrome-c:Fe3+ oxidoreductase activity" EXACT [EC:1.9.99.1] synonym: "iron-cytochrome c reductase activity" EXACT [EC:1.9.99.1] xref: EC:1.9.99.1 xref: GO:0047726 xref: MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN is_a: CCO:F0003267 ! oxidoreductase activity, acting on heme group of donors [Term] id: CCO:F0007029 name: isobutyryl-CoA mutase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methylpropanoyl-CoA = butanoyl-CoA." [EC:5.4.99.13, MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN] subset: gosubset_prok synonym: "2-methylpropanoyl-CoA CoA-carbonylmutase activity" EXACT [EC:5.4.99.13] synonym: "butyryl-CoA:isobutyryl-CoA mutase activity" EXACT [EC:5.4.99.13] synonym: "isobutyryl coenzyme A mutase activity" EXACT [EC:5.4.99.13] xref: EC:5.4.99.13 xref: GO:0047727 xref: MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0007030 name: carnitine 3-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + L-carnitine = NADH + 3-dehydrocarnitine." [EC:1.1.1.108, MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "carnitine:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.108] xref: EC:1.1.1.108 xref: GO:0047728 xref: MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007031 name: carnitine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: carnitine = 2-methylcholine + CO2." [EC:4.1.1.42, MetaCyc:CARNITINE-DECARBOXYLASE-RXN] synonym: "carnitine carboxy-lyase (2-methylcholine-forming)" EXACT [EC:4.1.1.42] synonym: "carnitine carboxy-lyase activity" EXACT [EC:4.1.1.42] xref: EC:4.1.1.42 xref: GO:0047729 xref: MetaCyc:CARNITINE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007032 name: carnosine synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine." [EC:6.3.2.11, MetaCyc:CARNOSINE-SYNTHASE-RXN] synonym: "carnosine synthetase activity" EXACT [EC:6.3.2.11] synonym: "carnosine-anserine synthetase activity" EXACT [EC:6.3.2.11] synonym: "carnosine-homocarnosine synthetase activity" EXACT [EC:6.3.2.11] synonym: "homocarnosine-carnosine synthetase activity" EXACT [EC:6.3.2.11] synonym: "L-histidine:beta-alanine ligase (AMP-forming)" EXACT [EC:6.3.2.11] xref: EC:6.3.2.11 xref: GO:0047730 xref: MetaCyc:CARNOSINE-SYNTHASE-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0007033 name: catechol oxidase (dimerizing) activity namespace: molecular_function def: "Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O." [EC:1.1.3.14, MetaCyc:CATECHOL-OXIDASE-(DIMERIZING)-RXN] synonym: "catechol:oxygen oxidoreductase (dimerizing)" EXACT [EC:1.1.3.14] xref: EC:1.1.3.14 xref: GO:0047731 xref: MetaCyc:CATECHOL-OXIDASE-(DIMERIZING)-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007034 name: CDP-abequose epimerase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose." [EC:5.1.3.10, MetaCyc:CDP-ABEQUOSE-EPIMERASE-RXN] synonym: "CDP-3,6-dideoxy-D-glucose 2-epimerase activity" EXACT [EC:5.1.3.10] synonym: "CDP-D-abequose 2-epimerase activity" EXACT [EC:5.1.3.10] synonym: "CDP-paratose 2-epimerase activity" EXACT [EC:5.1.3.10] synonym: "CDP-paratose epimerase activity" EXACT [EC:5.1.3.10] synonym: "CDP-tyvelose 2-epimerase activity" EXACT [EC:5.1.3.10] synonym: "cytidine diphosphate paratose-2-epimerase activity" EXACT [EC:5.1.3.10] synonym: "cytidine diphosphoabequose epimerase activity" EXACT [EC:5.1.3.10] synonym: "cytidine diphosphodideoxyglucose epimerase activity" EXACT [EC:5.1.3.10] synonym: "cytidine diphosphoparatose epimerase activity" EXACT [EC:5.1.3.10] xref: EC:5.1.3.10 xref: GO:0047732 xref: MetaCyc:CDP-ABEQUOSE-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007035 name: CDP-glucose 4,6-dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O." [EC:4.2.1.45, MetaCyc:CDP-GLUCOSE-4] subset: gosubset_prok synonym: "CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)" EXACT [EC:4.2.1.45] synonym: "CDP-glucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.45] synonym: "CDPglucose 4,6-dehydratase activity" EXACT [EC:4.2.1.45] synonym: "CDPglucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.45] synonym: "cytidine diphosphoglucose oxidoreductase activity" EXACT [EC:4.2.1.45] xref: EC:4.2.1.45 xref: GO:0047733 xref: MetaCyc:CDP-GLUCOSE-4 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007036 name: CDP-glycerol diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-glycerol + H2O = CMP + sn-glycerol 3-phosphate." [EC:3.6.1.16, MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN] synonym: "CDP-glycerol phosphoglycerohydrolase activity" EXACT [EC:3.6.1.16] synonym: "CDP-glycerol pyrophosphatase activity" EXACT [] synonym: "CDPglycerol diphosphatase activity" EXACT [EC:3.6.1.16] synonym: "CDPglycerol phosphoglycerohydrolase activity" EXACT [EC:3.6.1.16] synonym: "CDPglycerol pyrophosphatase activity" EXACT [EC:3.6.1.16] synonym: "cytidine diphosphoglycerol pyrophosphatase activity" EXACT [EC:3.6.1.16] xref: EC:3.6.1.16 xref: GO:0047734 xref: MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0007037 name: cellobiose dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor." [EC:1.1.99.18, MetaCyc:CELLOBIOSE-DEHYDROGENASE-(ACCEPTOR)-RXN] synonym: "CBOR activity" RELATED [EC:1.1.99.18] synonym: "CDH activity" RELATED [EC:1.1.99.18] synonym: "cellobiose dehydrogenase (quinone) activity" NARROW [EC:1.1.99.18] synonym: "cellobiose dehydrogenase activity" EXACT [EC:1.1.99.18] synonym: "cellobiose oxidase activity" EXACT [EC:1.1.99.18] synonym: "cellobiose oxidoreductase activity" EXACT [EC:1.1.99.18] synonym: "cellobiose-quinone oxidoreductase activity" NARROW [EC:1.1.99.18] synonym: "cellobiose:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.18] synonym: "cellobiose:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.18] synonym: "cellobiose:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.99.18] synonym: "phanerochaete chrysosporium cellobiose oxidoreductase activity" EXACT [EC:1.1.99.18] xref: EC:1.1.99.18 xref: GO:0047735 xref: GO:0047737 xref: MetaCyc:CELLOBIOSE-DEHYDROGENASE-(ACCEPTOR)-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007038 name: cellobiose epimerase activity namespace: molecular_function def: "Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose." [EC:5.1.3.11, MetaCyc:CELLOBIOSE-EPIMERASE-RXN] synonym: "cellobiose 2-epimerase activity" EXACT [EC:5.1.3.11] xref: EC:5.1.3.11 xref: GO:0047736 xref: MetaCyc:CELLOBIOSE-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007039 name: cellobiose phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose." [EC:2.4.1.20, MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN] subset: gosubset_prok synonym: "cellobiose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.20] xref: EC:2.4.1.20 xref: GO:0047738 xref: MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0007040 name: cephalosporin-C deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: cephalosporin C + H2O = deacetylcephalosporin C + acetate." [EC:3.1.1.41, MetaCyc:CEPHALOSPORIN-C-DEACETYLASE-RXN] subset: gosubset_prok synonym: "cephalosporin acetylesterase activity" EXACT [EC:3.1.1.41] synonym: "cephalosporin C acetyl-esterase activity" EXACT [EC:3.1.1.41] synonym: "cephalosporin C acetyl-hydrolase activity" EXACT [EC:3.1.1.41] synonym: "cephalosporin C acetylase activity" EXACT [EC:3.1.1.41] synonym: "cephalosporin C acetylesterase activity" EXACT [EC:3.1.1.41] synonym: "cephalosporin C deacetylase activity" EXACT [EC:3.1.1.41] synonym: "cephalosporin-C acetylhydrolase activity" EXACT [EC:3.1.1.41] xref: EC:3.1.1.41 xref: GO:0047739 xref: MetaCyc:CEPHALOSPORIN-C-DEACETYLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0007041 name: cephalosporin-C transaminase activity namespace: molecular_function def: "Catalysis of the reaction: cephalosporin C + pyruvate = 7-(5-carboxyl-5-oxopentanyl)-aminocephalosporinate + L-alanine." [EC:2.6.1.74, MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN] synonym: "cephalosporin C aminotransferase activity" EXACT [EC:2.6.1.74] synonym: "cephalosporin-C:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.74] synonym: "L-alanine:cephalosporin-C aminotransferase activity" EXACT [EC:2.6.1.74] xref: EC:2.6.1.74 xref: GO:0047740 xref: MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007042 name: cetraxate benzylesterase activity namespace: molecular_function def: "Catalysis of the reaction: cetraxate benzyl ester + H2O = cetraxate + benzyl alcohol." [EC:3.1.1.70, MetaCyc:CETRAXATE-BENZYLESTERASE-RXN] synonym: "cetraxate-benzyl-ester benzylhydrolase activity" EXACT [EC:3.1.1.70] xref: EC:3.1.1.70 xref: GO:0047741 xref: MetaCyc:CETRAXATE-BENZYLESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007043 name: chenodeoxycholoyltaurine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine." [EC:3.5.1.74, MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN] synonym: "chenodeoxycholoyltaurine amidohydrolase activity" EXACT [EC:3.5.1.74] xref: EC:3.5.1.74 xref: GO:0047742 xref: MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007044 name: chlordecone reductase activity namespace: molecular_function def: "Catalysis of the reaction: chlordecone alcohol + NADP+ = chlordecone + NADPH." [EC:1.1.1.225, MetaCyc:CHLORDECONE-REDUCTASE-RXN] synonym: "CDR activity" RELATED [EC:1.1.1.225] synonym: "chlordecone-alcohol:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.225] xref: EC:1.1.1.225 xref: GO:0047743 xref: MetaCyc:CHLORDECONE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007045 name: chloridazon-catechol dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)-3(2H)-pyridazinone." [EC:1.13.11.36, MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN] synonym: "5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.36] xref: EC:1.13.11.36 xref: GO:0047744 xref: MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007046 name: chlorogenate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: chlorogenate + H2O = caffeate + quinate." [EC:3.1.1.42, MetaCyc:CHLOROGENATE-HYDROLASE-RXN] synonym: "chlorogenase activity" EXACT [EC:3.1.1.42] synonym: "chlorogenic acid esterase activity" EXACT [EC:3.1.1.42] xref: EC:3.1.1.42 xref: GO:0047745 xref: MetaCyc:CHLOROGENATE-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007047 name: chlorophyllase activity namespace: molecular_function def: "Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide." [EC:3.1.1.14, MetaCyc:CHLOROPHYLLASE-RXN] synonym: "chlorophyll chlorophyllidohydrolase activity" EXACT [EC:3.1.1.14] xref: EC:3.1.1.14 xref: GO:0047746 xref: MetaCyc:CHLOROPHYLLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007048 name: cholate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA." [EC:6.2.1.7, MetaCyc:CHOLATE--COA-LIGASE-RXN] synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity" EXACT [EC:6.2.1.29] synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity" EXACT [] synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity" EXACT [EC:6.2.1.29] synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity" EXACT [EC:6.2.1.29] synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity" EXACT [EC:6.2.1.29] synonym: "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.29] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity" EXACT [EC:6.2.1.29] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.29] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity" EXACT [EC:6.2.1.29] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity" EXACT [EC:6.2.1.29] synonym: "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity" EXACT [EC:6.2.1.29] synonym: "BAL activity" RELATED [EC:6.2.1.29] synonym: "bile acid CoA ligase activity" RELATED [EC:6.2.1.29] synonym: "bile acid coenzyme A ligase activity" RELATED [EC:6.2.1.29] synonym: "cholate thiokinase activity" EXACT [EC:6.2.1.29] synonym: "cholate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.29] synonym: "cholic acid:CoA ligase activity" EXACT [EC:6.2.1.29] synonym: "cholic thiokinase activity" EXACT [EC:6.2.1.29] synonym: "choloyl coenzyme A synthetase activity" EXACT [EC:6.2.1.29] synonym: "choloyl-CoA synthetase activity" EXACT [EC:6.2.1.29] synonym: "cholyl-CoA synthetase activity" EXACT [EC:6.2.1.29] synonym: "THCA-CoA ligase activity" RELATED [EC:6.2.1.29] synonym: "trihydroxycoprostanoyl-CoA synthetase activity" RELATED [EC:6.2.1.29] xref: EC:6.2.1.29 xref: EC:6.2.1.7 xref: GO:0047477 xref: GO:0047747 xref: MetaCyc:6.2.1.29-RXN xref: MetaCyc:CHOLATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007049 name: cholestanetetraol 26-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH." [EC:1.1.1.161, MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN] synonym: "5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity" EXACT [EC:1.1.1.161] synonym: "5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase activity" EXACT [EC:1.1.1.161] synonym: "cholestanetetrol 26-dehydrogenase activity" EXACT [EC:1.1.1.161] synonym: "TEHC-NAD oxidoreductase activity" EXACT [EC:1.1.1.161] xref: EC:1.1.1.161 xref: GO:0047748 xref: MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007050 name: cholestanetriol 26-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O." [EC:1.14.13.15, MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN] synonym: "5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity" EXACT [EC:1.14.13.15] synonym: "5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity" BROAD [EC:1.14.13.15] synonym: "5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity" EXACT [EC:1.14.13.15] synonym: "5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity" EXACT [EC:1.14.13.15] synonym: "5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)" EXACT [EC:1.14.13.15] synonym: "cholestanetriol 26-hydroxylase activity" EXACT [] synonym: "cholesterol 27-hydroxylase activity" RELATED [EC:1.14.13.15] synonym: "CYP27A" RELATED [EC:1.14.13.15] synonym: "CYP27A1" RELATED [EC:1.14.13.15] synonym: "cytochrome P450 27A1' activity" NARROW [EC:1.14.13.15] synonym: "sterol 26-hydroxylase activity" BROAD [EC:1.14.13.15] synonym: "sterol 27-hydroxylase activity" RELATED [EC:1.14.13.15] xref: EC:1.14.13.15 xref: GO:0047749 xref: MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007051 name: cholestenol delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol." [EC:5.3.3.5, MetaCyc:CHOLESTENOL-DELTA-ISOMERASE-RXN] synonym: "cholestenol D-isomerase activity" EXACT [] synonym: "delta7-cholestenol delta7-delta8-isomerase activity" EXACT [EC:5.3.3.5] xref: EC:5.3.3.5 xref: GO:0047750 xref: MetaCyc:CHOLESTENOL-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0007052 name: cholestenone 5-alpha-reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5-alpha-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH." [EC:1.3.1.22, MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN] synonym: "3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity" EXACT [EC:1.3.1.22] synonym: "3-oxosteroid 5alpha-reductase activity" EXACT [EC:1.3.1.22] synonym: "3-oxosteroid delta4-dehydrogenase" BROAD [EC:1.3.1.22] synonym: "4-ene-3-oxosteroid 5alpha-reductase activity" EXACT [EC:1.3.1.22] synonym: "4-ene-5alpha-reductase activity" EXACT [EC:1.3.1.22] synonym: "5alpha-reductase" BROAD [EC:1.3.1.22] synonym: "cholest-4-en-3-one 5alpha-reductase activity" EXACT [EC:1.3.1.22] synonym: "cholestenone 5a-reductase activity" EXACT [] synonym: "cholestenone 5alpha-reductase activity" EXACT [EC:1.3.1.22] synonym: "delta4-3-ketosteroid 5alpha-oxidoreductase activity" EXACT [EC:1.3.1.22] synonym: "reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity" EXACT [EC:1.3.1.22] synonym: "steroid 5alpha-hydrogenase activity" EXACT [EC:1.3.1.22] synonym: "steroid 5alpha-reductase" BROAD [EC:1.3.1.22] synonym: "testosterone 5alpha-reductase" BROAD [EC:1.3.1.22] synonym: "testosterone delta4-5alpha-reductase activity" EXACT [EC:1.3.1.22] synonym: "testosterone delta4-hydrogenase activity" EXACT [EC:1.3.1.22] xref: EC:1.3.1.22 xref: GO:0047751 xref: MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007053 name: choline-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: choline sulfate + H2O = choline + sulfate." [EC:3.1.6.6, MetaCyc:CHOLINE-SULFATASE-RXN] subset: gosubset_prok synonym: "choline-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.6] synonym: "choline-sulphatase activity" EXACT [] xref: EC:3.1.6.6 xref: GO:0047753 xref: MetaCyc:CHOLINE-SULFATASE-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0007054 name: choline sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + choline = adenosine 3',5'-bisphosphate + choline sulfate." [EC:2.8.2.6, MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:choline sulfotransferase activity" EXACT [EC:2.8.2.6] synonym: "choline sulphokinase activity" EXACT [EC:2.8.2.6] synonym: "choline sulphotransferase activity" EXACT [] xref: EC:2.8.2.6 xref: GO:0047754 xref: MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007055 name: isocitrate epimerase activity namespace: molecular_function def: "Catalysis of the reaction: (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate = (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylate." [EC:5.1.2.6, MetaCyc:ISOCITRATE-EPIMERASE-RXN] synonym: "(1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase activity" EXACT [EC:5.1.2.6] xref: EC:5.1.2.6 xref: GO:0047755 xref: MetaCyc:ISOCITRATE-EPIMERASE-RXN is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0007056 name: chondroitin 4-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate." [EC:2.8.2.5, MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:chondroitin 4'-sulfotransferase activity" EXACT [EC:2.8.2.5] synonym: "chondroitin 4-sulphotransferase activity" EXACT [] xref: EC:2.8.2.5 xref: GO:0047756 xref: MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN is_a: CCO:F0008396 ! chondroitin sulfotransferase activity [Term] id: CCO:F0007057 name: chondroitin-glucuronate 5-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate." [EC:5.1.3.19, MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN] synonym: "chondroitin D-glucuronosyl 5-epimerase activity" EXACT [EC:5.1.3.19] synonym: "chondroitin-D-glucuronate 5-epimerase activity" EXACT [EC:5.1.3.19] synonym: "dermatan-sulfate 5-epimerase activity" EXACT [EC:5.1.3.19] synonym: "polyglucuronate 5-epimerase activity" RELATED [EC:5.1.3.19] synonym: "urunosyl C-5 epimerase activity" EXACT [EC:5.1.3.19] xref: EC:5.1.3.19 xref: GO:0047757 xref: MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007058 name: branched-chain fatty acid kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-methylpropanoate = ADP + 2-methylpropanoyl phosphate." [EC:2.7.2.14, MetaCyc:BRANCHED-CHAIN-FATTY-ACID-KINASE-RXN] synonym: "ATP:branched-chain-fatty-acid 1-phosphotransferase activity" EXACT [EC:2.7.2.14] synonym: "branched-chain-fatty-acid kinase activity" EXACT [] synonym: "isobutyrate kinase activity" NARROW [EC:2.7.2.14] xref: EC:2.7.2.14 xref: GO:0047758 xref: MetaCyc:BRANCHED-CHAIN-FATTY-ACID-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0007059 name: butanal dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+." [EC:1.2.1.57, MetaCyc:BUTANAL-DEHYDROGENASE-RXN] synonym: "butanal:NAD(P)+ oxidoreductase (CoA-acylating)" EXACT [EC:1.2.1.57] xref: EC:1.2.1.57 xref: GO:0047759 xref: MetaCyc:BUTANAL-DEHYDROGENASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007060 name: butyrate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA." [EC:6.2.1.2, MetaCyc:BUTYRATE--COA-LIGASE-RXN] synonym: "acyl-activating enzyme activity" RELATED [EC:6.2.1.2] synonym: "butanoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.2] synonym: "butyryl-CoA synthetase activity" EXACT [EC:6.2.1.2] synonym: "butyryl-coenzyme A synthetase activity" EXACT [EC:6.2.1.2] synonym: "fatty acid activating enzyme" RELATED [EC:6.2.1.2] synonym: "fatty acid thiokinase (medium chain) activity" RELATED [EC:6.2.1.2] synonym: "fatty acyl coenzyme A synthetase activity" EXACT [EC:6.2.1.2] synonym: "L-(+)-3-hydroxybutyryl CoA ligase activity" EXACT [EC:6.2.1.2] synonym: "medium chain acyl-CoA synthetase activity" EXACT [EC:6.2.1.2] synonym: "short-chain acyl-CoA synthetase activity" EXACT [EC:6.2.1.2] xref: EC:6.2.1.2 xref: GO:0047760 xref: MetaCyc:BUTYRATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007061 name: butyrate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate." [EC:2.7.2.7, MetaCyc:BUTYRATE-KINASE-RXN] subset: gosubset_prok synonym: "ATP:butanoate 1-phosphotransferase activity" EXACT [EC:2.7.2.7] xref: EC:2.7.2.7 xref: GO:0047761 xref: MetaCyc:BUTYRATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0007062 name: caffeate 3,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxy-trans-cinnamate + O2 = 3-(2-carboxyethenyl)-cis,cis-muconate." [EC:1.13.11.22, MetaCyc:CAFFEATE-3] synonym: "3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.22] xref: EC:1.13.11.22 xref: GO:0047762 xref: MetaCyc:CAFFEATE-3 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007063 name: caffeate O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate." [EC:2.1.1.68, MetaCyc:CAFFEATE-O-METHYLTRANSFERASE-RXN] synonym: "caffeate 3-O-methyltransferase activity" EXACT [EC:2.1.1.68] synonym: "caffeate methyltransferase activity" EXACT [EC:2.1.1.68] synonym: "S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase activity" EXACT [EC:2.1.1.68] synonym: "S-adenosyl-L-methionine:caffeic acid-O-methyltransferase activity" EXACT [EC:2.1.1.68] xref: EC:2.1.1.68 xref: GO:0047763 xref: MetaCyc:CAFFEATE-O-METHYLTRANSFERASE-RXN is_a: CCO:F0001758 ! O-methyltransferase activity [Term] id: CCO:F0007064 name: caldesmon kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate." [GOC:curators] xref: GO:0047764 is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0007065 name: caldesmon-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate." [EC:3.1.3.55, MetaCyc:CALDESMON-PHOSPHATASE-RXN] synonym: "caldesmon-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.55] synonym: "smooth muscle caldesmon phosphatase activity" EXACT [EC:3.1.3.55] synonym: "SMP-I" RELATED [EC:3.1.3.55] xref: EC:3.1.3.55 xref: GO:0047765 xref: MetaCyc:CALDESMON-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007066 name: carbamoyl-serine ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: O-carbamoyl-L-serine + H2O = pyruvate + 2 NH3 + CO2." [EC:4.3.1.13, MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN] synonym: "carbamoylserine deaminase activity" EXACT [EC:4.3.1.13] synonym: "O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming)" EXACT [EC:4.3.1.13] synonym: "O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming)" EXACT [EC:4.3.1.13] synonym: "O-carbamoyl-L-serine deaminase activity" EXACT [EC:4.3.1.13] xref: EC:4.3.1.13 xref: GO:0047766 xref: MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0007067 name: carboxy-cis,cis-muconate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate." [EC:5.5.1.5, MetaCyc:CARBOXY-CIS] synonym: "3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)" EXACT [EC:5.5.1.5] synonym: "3-carboxy-cis,cis-muconate lactonizing enzyme activity" EXACT [EC:5.5.1.5] synonym: "3-carboxymuconate cyclase activity" EXACT [EC:5.5.1.5] xref: EC:5.5.1.5 xref: GO:0047768 xref: MetaCyc:CARBOXY-CIS is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0007068 name: arogenate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2." [EC:4.2.1.91, MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN] subset: gosubset_prok synonym: "carboxycyclohexadienyl dehydratase activity" EXACT [] synonym: "L-arogenate hydro-lyase (decarboxylating)" EXACT [EC:4.2.1.91] synonym: "L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)" EXACT [EC:4.2.1.91] xref: EC:4.2.1.91 xref: GO:0047769 xref: MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007069 name: carboxylate reductase activity namespace: molecular_function def: "Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor." [EC:1.2.99.6, MetaCyc:CARBOXYLATE-REDUCTASE-RXN] synonym: "aldehyde:(acceptor) oxidoreductase activity" EXACT [EC:1.2.99.6] synonym: "aldehyde:acceptor oxidoreductase activity" EXACT [EC:1.2.99.6] synonym: "carboxylic acid reductase activity" EXACT [EC:1.2.99.6] xref: EC:1.2.99.6 xref: GO:0047770 xref: MetaCyc:CARBOXYLATE-REDUCTASE-RXN is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0007070 name: carboxymethylhydantoinase activity namespace: molecular_function def: "Catalysis of the reaction: L-5-carboxymethylhydantoin + H2O = N-carbamoyl-L-aspartate." [EC:3.5.2.4, MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN] synonym: "hydantoin hydrolase activity" EXACT [EC:3.5.2.4] synonym: "L-5-carboxymethylhydantoin amidohydrolase activity" EXACT [EC:3.5.2.4] xref: EC:3.5.2.4 xref: GO:0047771 xref: MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0007071 name: carboxymethyloxysuccinate lyase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2 carboxymethyloxysuccinate = 2 glycolate + 2 fumarate." [EC:4.2.99.12, MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN] synonym: "carboxymethyloxysuccinate glycolate-lyase (fumarate-forming)" EXACT [EC:4.2.99.12] synonym: "carboxymethyloxysuccinate glycolate-lyase activity" EXACT [EC:4.2.99.12] xref: EC:4.2.99.12 xref: GO:0047772 xref: MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0007072 name: carnitinamidase activity namespace: molecular_function def: "Catalysis of the reaction: L-carnitinamide + H2O = L-carnitine + NH3." [EC:3.5.1.73, MetaCyc:CARNITINAMIDASE-RXN] synonym: "carnitine amidase activity" EXACT [EC:3.5.1.73] synonym: "L-carnitinamidase activity" EXACT [EC:3.5.1.73] synonym: "L-carnitinamide amidohydrolase activity" EXACT [EC:3.5.1.73] synonym: "L-carnitine amidase activity" EXACT [EC:3.5.1.73] xref: EC:3.5.1.73 xref: GO:0047773 xref: MetaCyc:CARNITINAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007073 name: cis-2-enoyl-CoA reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH." [EC:1.3.1.37, MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-(NADPH)-RXN] synonym: "acyl-CoA:NADP+ cis-2-oxidoreductase activity" EXACT [EC:1.3.1.37] synonym: "cis-2-enoyl-coenzyme A reductase activity" EXACT [EC:1.3.1.37] synonym: "NADPH-dependent cis-enoyl-CoA reductase activity" EXACT [EC:1.3.1.37] synonym: "reductase, cis-2-enoyl coenzyme A" EXACT [EC:1.3.1.37] xref: EC:1.3.1.37 xref: GO:0047774 xref: MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-(NADPH)-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007074 name: citramalate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA." [EC:2.8.3.11, MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN] synonym: "acetyl-CoA:citramalate CoA-transferase activity" EXACT [EC:2.8.3.11] xref: EC:2.8.3.11 xref: GO:0047775 xref: MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0007075 name: citramalate lyase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-citramalate = acetate + pyruvate." [EC:4.1.3.22, MetaCyc:CITRAMALATE-LYASE-RXN] synonym: "(+)-citramalate pyruvate-lyase activity" EXACT [EC:4.1.3.22] synonym: "(3S)-citramalate pyruvate-lyase (acetate-forming)" EXACT [EC:4.1.3.22] synonym: "(3S)-citramalate pyruvate-lyase activity" EXACT [EC:4.1.3.22] synonym: "(S)-citramalate lyase activity" EXACT [EC:4.1.3.22] synonym: "citramalate pyruvate lyase activity" EXACT [EC:4.1.3.22] synonym: "citramalate pyruvate-lyase activity" EXACT [EC:4.1.3.22] synonym: "citramalate synthetase activity" EXACT [EC:4.1.3.22] synonym: "citramalic synthase activity" EXACT [EC:4.1.3.22] synonym: "citramalic-condensing enzyme" RELATED [EC:4.1.3.22] xref: EC:4.1.3.22 xref: GO:0047776 xref: MetaCyc:CITRAMALATE-LYASE-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0007076 name: citramalyl-CoA lyase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate." [EC:4.1.3.25, MetaCyc:CITRAMALYL-COA-LYASE-RXN] synonym: "(+)-CMA-CoA lyase activity" EXACT [EC:4.1.3.25] synonym: "(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.25] synonym: "(3S)-citramalyl-CoA pyruvate-lyase activity" EXACT [EC:4.1.3.25] synonym: "citramalyl coenzyme A lyase activity" EXACT [EC:4.1.3.25] xref: EC:4.1.3.25 xref: GO:0047777 xref: MetaCyc:CITRAMALYL-COA-LYASE-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0007078 name: citrate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + citrate + CoA = ADP + phosphate + (3S)-citryl-CoA." [EC:6.2.1.18, MetaCyc:CITRATE--COA-LIGASE-RXN] synonym: "citrate thiokinase activity" EXACT [EC:6.2.1.18] synonym: "citrate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.18] synonym: "citrate:CoA ligase activity" EXACT [EC:6.2.1.18] synonym: "citryl-CoA synthetase activity" EXACT [EC:6.2.1.18] xref: EC:6.2.1.18 xref: GO:0047779 xref: MetaCyc:CITRATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007079 name: citrate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: citrate = cis-aconitate + H2O." [EC:4.2.1.4, MetaCyc:CITRATE-DEHYDRATASE-RXN] synonym: "citrate hydro-lyase (cis-aconitate-forming)" EXACT [EC:4.2.1.4] synonym: "citrate hydro-lyase activity" BROAD [EC:4.2.1.4] xref: EC:4.2.1.4 xref: GO:0047780 xref: MetaCyc:CITRATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007080 name: citrullinase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine." [EC:3.5.1.20, MetaCyc:CITRULLINASE-RXN] synonym: "citrulline hydrolase activity" EXACT [EC:3.5.1.20] synonym: "citrulline ureidase activity" EXACT [EC:3.5.1.20] synonym: "L-citrulline 5-N-carbamoyldihydrolase activity" EXACT [EC:3.5.1.20] synonym: "L-citrulline N5-carbamoyldihydrolase activity" EXACT [EC:3.5.1.20] xref: EC:3.5.1.20 xref: GO:0047781 xref: MetaCyc:CITRULLINASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007081 name: coniferin beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol." [EC:3.2.1.126, MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN] synonym: "coniferin b-glucosidase activity" EXACT [] synonym: "coniferin beta-D-glucosidase activity" EXACT [EC:3.2.1.126] synonym: "coniferin-hydrolyzing beta-glucosidase activity" EXACT [EC:3.2.1.126] xref: EC:3.2.1.126 xref: GO:0047782 xref: MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007082 name: corticosterone 18-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O." [EC:1.14.15.5, MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN] synonym: "corticosterone 18-hydroxylase activity" EXACT [] synonym: "corticosterone methyl oxidase activity" RELATED [EC:1.14.15.5] synonym: "corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)" EXACT [EC:1.14.15.5] xref: EC:1.14.15.5 xref: GO:0047783 xref: MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007083 name: cortisol O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate." [EC:2.3.1.27, MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:cortisol O-acetyltransferase activity" EXACT [EC:2.3.1.27] synonym: "corticosteroid acetyltransferase activity" EXACT [EC:2.3.1.27] synonym: "corticosteroid-21-O-acetyltransferase activity" EXACT [EC:2.3.1.27] synonym: "cortisol acetyltransferase activity" EXACT [EC:2.3.1.27] xref: EC:2.3.1.27 xref: GO:0047784 xref: MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0007084 name: cortisol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cortisol = adenosine 3',5'-bisphosphate + cortisol 21-sulfate." [EC:2.8.2.18, MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase activity" EXACT [EC:2.8.2.18] synonym: "cortisol sulphotransferase activity" EXACT [] synonym: "glucocorticoid sulfotransferase activity" EXACT [EC:2.8.2.18] synonym: "glucocorticosteroid sulfotransferase activity" BROAD [EC:2.8.2.18] xref: EC:2.8.2.18 xref: GO:0047785 xref: MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007085 name: cortisone alpha-reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4,5-alpha-dihydrocortisone + NADP+ = cortisone + NADPH." [EC:1.3.1.4, MetaCyc:CORTISONE-ALPHA-REDUCTASE-RXN] synonym: "4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase activity" EXACT [EC:1.3.1.4] synonym: "cortisone a-reductase activity" EXACT [] synonym: "cortisone delta4-5alpha-reductase activity" EXACT [EC:1.3.1.4] synonym: "delta4-3-ketosteroid reductase (5alpha)" EXACT [EC:1.3.1.4] synonym: "delta4-3-oxosteroid-5alpha-reductase" BROAD [EC:1.3.1.4] synonym: "delta4-5alpha-reductase activity" EXACT [EC:1.3.1.4] synonym: "microsomal steroid reductase (5alpha)" EXACT [EC:1.3.1.4] synonym: "NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase activity" EXACT [EC:1.3.1.4] xref: EC:1.3.1.4 xref: GO:0047786 xref: MetaCyc:CORTISONE-ALPHA-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007086 name: delta4-3-oxosteroid 5beta-reductase activity namespace: molecular_function def: "Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+." [EC:1.3.1.3, MetaCyc:CORTISONE-BETA-REDUCTASE-RXN] synonym: "3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity" EXACT [EC:1.3.1.23] synonym: "3-oxo-Delta(4)-steroid 5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "3-oxo-delta4-steroid 5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity" EXACT [EC:1.3.1.23] synonym: "5-beta-reductase activity" BROAD [EC:1.3.1.23] synonym: "5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity" EXACT [EC:1.3.1.23] synonym: "5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "androstenedione 5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "androstenedione 5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "cholestenone 5-beta-reductase activity" EXACT [] synonym: "cholestenone 5b-reductase activity" EXACT [] synonym: "cholestenone 5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "cortisone 5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "cortisone 5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "cortisone b-reductase activity" EXACT [] synonym: "cortisone beta-reductase activity" EXACT [] synonym: "cortisone delta(4)-5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "cortisone delta4-5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "delta(4)-3-ketosteroid 5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "delta(4)-5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "delta(4)-hydrogenase activity" EXACT [EC:1.3.1.23] synonym: "delta-4-3-oxosteroid 5-beta-reductase activity" EXACT [] synonym: "delta4-3-ketosteroid 5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "delta4-5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "delta4-hydrogenase activity" EXACT [EC:1.3.1.23] synonym: "steroid 5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "steroid 5beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "testosterone 5-beta-reductase activity" EXACT [EC:1.3.1.23] synonym: "testosterone 5beta-reductase activity" EXACT [EC:1.3.1.23] xref: EC:1.3.1.3 xref: GO:0047752 xref: GO:0047787 xref: MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN xref: MetaCyc:CORTISONE-BETA-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007087 name: 2-coumarate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD+ = 2-coumarate + NADH." [EC:1.3.1.11, MetaCyc:COUMARATE-REDUCTASE-RXN] synonym: "3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.11] synonym: "coumarate reductase activity" EXACT [] synonym: "melilotate dehydrogenase activity" EXACT [EC:1.3.1.11] xref: EC:1.3.1.11 xref: GO:0047788 xref: MetaCyc:COUMARATE-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007088 name: creatininase activity namespace: molecular_function def: "Catalysis of the reaction: creatinine + H2O = creatine." [EC:3.5.2.10, MetaCyc:CREATININASE-RXN] subset: gosubset_prok synonym: "creatinine amidohydrolase activity" EXACT [EC:3.5.2.10] synonym: "creatinine hydrolase" BROAD [EC:3.5.2.10] xref: EC:3.5.2.10 xref: GO:0047789 xref: MetaCyc:CREATININASE-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0007089 name: creatinine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3." [EC:3.5.4.21, MetaCyc:CREATININE-DEAMINASE-RXN] subset: gosubset_prok synonym: "creatinine desiminase activity" EXACT [EC:3.5.4.21] synonym: "creatinine hydrolase" BROAD [EC:3.5.4.21] synonym: "creatinine iminohydrolase activity" EXACT [EC:3.5.4.21] xref: EC:3.5.4.21 xref: GO:0047790 xref: MetaCyc:CREATININE-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007090 name: cucurbitacin delta23-reductase activity namespace: molecular_function def: "Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+." [EC:1.3.1.5, MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN] synonym: "23,24-dihydrocucurbitacin:NAD(P)+ delta23-oxidoreductase activity" EXACT [EC:1.3.1.5] synonym: "cucurbitacin D23-reductase activity" EXACT [] synonym: "cucurbitacin delta(23) reductase activity" EXACT [] synonym: "NAD(P)H: cucurbitacin B delta23-oxidoreductase activity" EXACT [EC:1.3.1.5] xref: EC:1.3.1.5 xref: GO:0047791 xref: MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007091 name: cyanohydrin beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDPglucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside." [EC:2.4.1.85, MetaCyc:CYANOHYDRIN-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "cyanohydrin b-glucosyltransferase activity" EXACT [] synonym: "UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.85] synonym: "UDP-glucose-p-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.85] synonym: "UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.85] synonym: "UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase activity" EXACT [EC:2.4.1.85] synonym: "UGT85B1 activity" NARROW [EC:2.4.1.85] synonym: "uridine diphosphoglucose-cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.85] synonym: "uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase activity" EXACT [EC:2.4.1.85] synonym: "uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase activity" EXACT [EC:2.4.1.85] xref: EC:2.4.1.85 xref: GO:0047792 xref: MetaCyc:CYANOHYDRIN-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007092 name: cycloeucalenol cycloisomerase activity namespace: molecular_function def: "Catalysis of the reaction: cycloeucalenol = obtusifoliol." [EC:5.5.1.9, MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN] synonym: "cycloeucalenol lyase (cyclopropane-decyclizing)" EXACT [EC:5.5.1.9] synonym: "cycloeucalenol--obtusifoliol isomerase activity" EXACT [EC:5.5.1.9] synonym: "cycloeucalenol-obtusifoliol isomerase activity" EXACT [] xref: EC:5.5.1.9 xref: GO:0047793 xref: MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0007093 name: cyclohexadienyl dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2." [EC:1.3.1.43, MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "arogenate dehydrogenase activity" EXACT [EC:1.3.1.43] synonym: "arogenic dehydrogenase activity" EXACT [EC:1.3.1.43] synonym: "L-arogenate:NAD(+) oxidoreductase activity" EXACT [EC:1.3.1.43] synonym: "L-arogenate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.3.1.43] synonym: "L-arogenate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.43] synonym: "pretyrosine dehydrogenase activity" EXACT [EC:1.3.1.43] xref: EC:1.3.1.43 xref: GO:0047794 xref: MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007094 name: cyclohexane-1,2-diol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH." [EC:1.1.1.174, MetaCyc:CYCLOHEXANE-1] synonym: "trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.174] xref: EC:1.1.1.174 xref: GO:0047795 xref: MetaCyc:CYCLOHEXANE-1 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007095 name: cyclohexane-1,3-dione hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohexane-1,3-dione + H2O = 5-oxohexanoate." [EC:3.7.1.10, MetaCyc:CYCLOHEXANE-1] synonym: "1,3-cyclohexanedione hydrolase activity" EXACT [EC:3.7.1.10] synonym: "cyclohexane-1,3-dione acylhydrolase (decyclizing)" EXACT [EC:3.7.1.10] xref: EC:3.7.1.10 xref: GO:0047796 xref: MetaCyc:CYCLOHEXANE-1 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0007096 name: cyclohexanone dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cyclohexanone + acceptor = cyclohex-2-enone + reduced acceptor." [EC:1.3.99.14, MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN] synonym: "cyclohexanone:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.3.99.14] synonym: "cyclohexanone:acceptor 2-oxidoreductase activity" EXACT [EC:1.3.99.14] xref: EC:1.3.99.14 xref: GO:0047797 xref: MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0007097 name: cyclomaltodextrinase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin." [EC:3.2.1.54, MetaCyc:CYCLOMALTODEXTRINASE-RXN] subset: gosubset_prok synonym: "cyclodextrinase activity" EXACT [EC:3.2.1.54] synonym: "cycloheptaglucanase activity" EXACT [EC:3.2.1.54] synonym: "cyclohexaglucanase activity" EXACT [EC:3.2.1.54] synonym: "cyclomaltodextrin dextrin-hydrolase (decyclizing)" EXACT [EC:3.2.1.54] xref: EC:3.2.1.54 xref: GO:0047798 xref: MetaCyc:CYCLOMALTODEXTRINASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007098 name: cyclopentanone monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: cyclopentanone + NADPH + O2 = 5-valerolactone + NADP+ + H2O." [EC:1.14.13.16, MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN] synonym: "cyclopentanone 1,2-monooxygenase activity" EXACT [EC:1.14.13.16] synonym: "cyclopentanone oxygenase activity" EXACT [EC:1.14.13.16] synonym: "cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)" EXACT [EC:1.14.13.16] xref: EC:1.14.13.16 xref: GO:0047799 xref: MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007099 name: cysteamine dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: cysteamine + O2 = hypotaurine." [EC:1.13.11.19, MetaCyc:CYSTEAMINE-DIOXYGENASE-RXN] synonym: "2-aminoethanethiol:oxygen oxidoreductase activity" EXACT [EC:1.13.11.19] synonym: "cysteamine oxygenase activity" EXACT [EC:1.13.11.19] synonym: "cysteamine:oxygen oxidoreductase activity" EXACT [EC:1.13.11.19] synonym: "persulfurase activity" RELATED [EC:1.13.11.19] xref: EC:1.13.11.19 xref: GO:0047800 xref: MetaCyc:CYSTEAMINE-DIOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007100 name: cysteine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate." [EC:2.6.1.3, MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN] synonym: "CGT" RELATED [EC:2.6.1.3] synonym: "cysteine aminotransferase activity" EXACT [] synonym: "L-cysteine aminotransferase activity" EXACT [EC:2.6.1.3] synonym: "L-cysteine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.3] xref: EC:2.6.1.3 xref: GO:0047801 xref: MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007101 name: cysteine-conjugate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate = S-(4-bromophenyl)-mercaptopyruvate + L-glutamate." [EC:2.6.1.75, MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN] synonym: "cysteine conjugate aminotransferase activity" EXACT [EC:2.6.1.75] synonym: "cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1)" EXACT [EC:2.6.1.75] synonym: "S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.75] xref: EC:2.6.1.75 xref: GO:0047802 xref: MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007102 name: cysteine lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-cysteine + SO3(2-) (sulfite) = L-cysteate + sulfide." [EC:4.4.1.10, MetaCyc:CYSTEINE-LYASE-RXN] synonym: "cysteine (sulfite) lyase activity" EXACT [EC:4.4.1.10] synonym: "L-cysteine hydrogen-sulfide-lyase (adding sulfite)" EXACT [EC:4.4.1.10] synonym: "L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming)" EXACT [EC:4.4.1.10] xref: EC:4.4.1.10 xref: GO:0047803 xref: MetaCyc:CYSTEINE-LYASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007103 name: cysteine-S-conjugate beta-lyase activity namespace: molecular_function def: "Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate." [EC:4.4.1.13, MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN] subset: gosubset_prok synonym: "cysteine conjugate beta-lyase activity" EXACT [EC:4.4.1.13] synonym: "cysteine-S-conjugate b-lyase activity" EXACT [] synonym: "glutamine transaminase K/cysteine conjugate beta-lyase activity" EXACT [EC:4.4.1.13] synonym: "L-cysteine-S-conjugate thiol-lyase (deaminating) activity" EXACT [EC:4.4.1.13] synonym: "L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.13] xref: EC:4.4.1.13 xref: GO:0047804 xref: MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007104 name: cytidylate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate." [EC:4.6.1.6, MetaCyc:CYTIDYLATE-CYCLASE-RXN] synonym: "3',5'-cyclic-CMP synthase activity" EXACT [EC:4.6.1.6] synonym: "3'5'-cyclic-CMP synthase activity" EXACT [EC:4.6.1.6] synonym: "CTP diphosphate-lyase (cyclizing)" EXACT [EC:4.6.1.6] synonym: "CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)" EXACT [EC:4.6.1.6] synonym: "cytidyl cyclase activity" EXACT [EC:4.6.1.6] synonym: "cytidylyl cyclase activity" EXACT [EC:4.6.1.6] xref: EC:4.6.1.6 xref: GO:0047805 xref: MetaCyc:CYTIDYLATE-CYCLASE-RXN is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003413 ! phosphorus-oxygen lyase activity [Term] id: CCO:F0007105 name: cytochrome-c3 hydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3." [EC:1.12.2.1, MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN] subset: gosubset_prok synonym: "cytochrome c3 reductase activity" EXACT [EC:1.12.2.1] synonym: "cytochrome hydrogenase activity" BROAD [EC:1.12.2.1] synonym: "H(2):ferricytochrome c3 oxidoreductase activity" EXACT [EC:1.12.2.1] synonym: "H2:ferricytochrome c3 oxidoreductase activity" EXACT [EC:1.12.2.1] synonym: "hydrogen:ferricytochrome-c3 oxidoreductase activity" EXACT [EC:1.12.2.1] xref: EC:1.12.2.1 xref: GO:0047806 xref: MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN xref: UM-BBD_enzymeID:e0481 is_a: CCO:F0003283 ! oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor [Term] id: CCO:F0007106 name: cytokinin 7-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + N6-alkylaminopurine = UDP + N6-alkylaminopurine-7-beta-D-glucoside." [EC:2.4.1.118, MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "cytokinin 7-b-glucosyltransferase activity" EXACT [] synonym: "cytokinin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] synonym: "UDP-glucose-zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] synonym: "UDP-glucose:zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] synonym: "UDPglucose:zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] synonym: "uridine diphosphoglucose-zeatin 7-glucosyltransferase activity" EXACT [EC:2.4.1.118] xref: EC:2.4.1.118 xref: GO:0047807 xref: MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007107 name: D(-)-tartrate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (S,S)-tartrate = oxaloacetate + H2O." [EC:4.2.1.81, MetaCyc:D(-)-TARTRATE-DEHYDRATASE-RXN] synonym: "(S,S)-tartrate hydro-lyase (oxaloacetate-forming)" EXACT [EC:4.2.1.81] synonym: "(S,S)-tartrate hydro-lyase activity" EXACT [EC:4.2.1.81] synonym: "D-tartrate dehydratase activity" EXACT [EC:4.2.1.81] xref: EC:4.2.1.81 xref: GO:0047808 xref: MetaCyc:D(-)-TARTRATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007108 name: D-2-hydroxy-acid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-lactate + acceptor = pyruvate + reduced acceptor." [EC:1.1.99.6, MetaCyc:D-2-HYDROXY-ACID-DEHYDROGENASE-RXN] synonym: "(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity" EXACT [EC:1.1.99.6] synonym: "2-hydroxy acid dehydrogenase activity" EXACT [EC:1.1.99.6] xref: EC:1.1.99.6 xref: GO:0047809 xref: MetaCyc:D-2-HYDROXY-ACID-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007109 name: D-alanine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate." [EC:2.6.1.21, MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN] subset: gosubset_prok synonym: "D-alanine aminotransferase activity" EXACT [] synonym: "D-alanine-D-glutamate transaminase activity" EXACT [EC:2.6.1.21] synonym: "D-alanine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.21] synonym: "D-amino acid aminotransferase activity" BROAD [EC:2.6.1.21] synonym: "D-amino acid transaminase activity" BROAD [EC:2.6.1.21] synonym: "D-amino-acid transaminase activity" EXACT [EC:2.6.1.21] synonym: "D-aspartate aminotransferase activity" RELATED [EC:2.6.1.21] synonym: "D-aspartate transaminase activity" RELATED [EC:2.6.1.21] synonym: "D-aspartic aminotransferase activity" RELATED [EC:2.6.1.21] xref: EC:2.6.1.21 xref: GO:0047810 xref: MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007110 name: D-alanine gamma-glutamyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamine + D-alanine = NH3 + g-L-glutamyl-D-alanine." [EC:2.3.2.14, MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN] synonym: "D-alanine g-glutamyltransferase activity" EXACT [] synonym: "L-glutamine:D-alanine gamma-glutamyltransferase activity" EXACT [EC:2.3.2.14] xref: EC:2.3.2.14 xref: GO:0047811 xref: MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0007111 name: D-amino-acid N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid." [EC:2.3.1.36, MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:D-amino-acid N-acetyltransferase activity" EXACT [EC:2.3.1.36] synonym: "D-amino acid acetyltransferase activity" EXACT [EC:2.3.1.36] synonym: "D-amino acid-alpha-N-acetyltransferase activity" EXACT [EC:2.3.1.36] xref: EC:2.3.1.36 xref: GO:0047812 xref: MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0007112 name: D-arabinitol 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH." [EC:1.1.1.11, MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN] subset: gosubset_prok xref: EC:1.1.1.11 xref: GO:0047813 xref: MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007113 name: D-arabinokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-arabinose = ADP + D-arabinose 5-phosphate." [EC:2.7.1.54, MetaCyc:D-ARABINOKINASE-RXN] synonym: "ATP:D-arabinose 5-phosphotransferase activity" EXACT [EC:2.7.1.54] synonym: "D-arabinokinase (phosphorylating)" EXACT [EC:2.7.1.54] xref: EC:2.7.1.54 xref: GO:0047814 xref: MetaCyc:D-ARABINOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007114 name: D-arabinonolactonase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinono-1,4-lactone + H2O = D-arabinonate." [EC:3.1.1.30, MetaCyc:D-ARABINONOLACTONASE-RXN] synonym: "D-arabinono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.30] xref: EC:3.1.1.30 xref: GO:0047815 xref: MetaCyc:D-ARABINONOLACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007115 name: D-arabinose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH." [EC:1.1.1.116, MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN] synonym: "arabinose(fucose)dehydrogenase activity" EXACT [EC:1.1.1.116] synonym: "D-arabinose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.116] synonym: "NAD-pentose-dehydrogenase activity" EXACT [EC:1.1.1.116] xref: EC:1.1.1.116 xref: GO:0047816 xref: MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007116 name: D-arginase activity namespace: molecular_function def: "Catalysis of the reaction: D-arginine + H2O = D-ornithine + urea." [EC:3.5.3.10, MetaCyc:D-ARGINASE-RXN] synonym: "D-arginine amidinohydrolase activity" EXACT [EC:3.5.3.10] xref: EC:3.5.3.10 xref: GO:0047817 xref: MetaCyc:D-ARGINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007117 name: D-fuconate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H2O." [EC:4.2.1.67, MetaCyc:D-FUCONATE-HYDRATASE-RXN] synonym: "D-fuconate hydratase activity" EXACT [] synonym: "D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming)" EXACT [EC:4.2.1.67] synonym: "D-fuconate hydro-lyase activity" EXACT [EC:4.2.1.67] xref: EC:4.2.1.67 xref: GO:0047818 xref: MetaCyc:D-FUCONATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007118 name: D-glutamate(D-aspartate) oxidase activity namespace: molecular_function def: "Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2." [EC:1.4.3.15, MetaCyc:D-GLUTAMATE(D-ASPARTATE)-OXIDASE-RXN] synonym: "D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.15] synonym: "D-glutamic-aspartic oxidase activity" EXACT [EC:1.4.3.15] synonym: "D-monoaminodicarboxylic acid oxidase activity" EXACT [EC:1.4.3.15] xref: EC:1.4.3.15 xref: GO:0047819 xref: MetaCyc:D-GLUTAMATE(D-ASPARTATE)-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0007119 name: D-glutamate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H2O." [EC:4.2.1.48, MetaCyc:D-GLUTAMATE-CYCLASE-RXN] synonym: "D-glutamate hydro-lyase (cyclizing)" EXACT [EC:4.2.1.48] synonym: "D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)" EXACT [EC:4.2.1.48] xref: EC:4.2.1.48 xref: GO:0047820 xref: MetaCyc:D-GLUTAMATE-CYCLASE-RXN is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007120 name: D-glutamate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2; D-aspartate + H2O = oxaloacetate + NH3 + H2O2." [BRENDA:1.4.3.15, EC:1.4.3.7, MetaCyc:D-GLUTAMATE-OXIDASE-RXN] synonym: "D-glutamate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.7] synonym: "D-glutamic acid oxidase activity" EXACT [EC:1.4.3.7] synonym: "D-glutamic oxidase activity" EXACT [EC:1.4.3.7] xref: EC:1.4.3.7 xref: GO:0047821 xref: MetaCyc:D-GLUTAMATE-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0007121 name: hypotaurine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: hypotaurine + H2O + NAD+ = taurine + NADH." [EC:1.8.1.3, MetaCyc:HYPOTAURINE-DEHYDROGENASE-RXN] synonym: "hypotaurine:NAD+ oxidoreductase activity" EXACT [EC:1.8.1.3] xref: EC:1.8.1.3 xref: GO:0047822 xref: MetaCyc:HYPOTAURINE-DEHYDROGENASE-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007122 name: D-glutamyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide." [EC:2.3.2.1, MetaCyc:D-GLUTAMYLTRANSFERASE-RXN] synonym: "D-gamma-glutamyl transpeptidase activity" EXACT [EC:2.3.2.1] synonym: "D-glutamyl transpeptidase activity" EXACT [EC:2.3.2.1] synonym: "glutamine:D-glutamyl-peptide 5-glutamyltransferase activity" EXACT [EC:2.3.2.1] xref: EC:2.3.2.1 xref: GO:0047823 xref: MetaCyc:D-GLUTAMYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0007123 name: D-iditol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH." [EC:1.1.1.15, MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN] xref: EC:1.1.1.15 xref: GO:0047824 xref: MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor is_a: CCO:F0004651 ! hexitol dehydrogenase activity [Term] id: CCO:F0007124 name: D-lactate-2-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-O-sulfolactate + H2O = (S)-lactate + SO4(2-) (sulfate)." [EC:3.1.6.17, MetaCyc:D-LACTATE-2-SULFATASE-RXN] synonym: "(S)-2-O-sulfolactate 2-sulfohydrolase activity" EXACT [EC:3.1.6.17] synonym: "D-lactate-2-sulphatase activity" EXACT [] xref: EC:3.1.6.17 xref: GO:0047825 xref: MetaCyc:D-LACTATE-2-SULFATASE-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0007125 name: D-lysine 5,6-aminomutase activity namespace: molecular_function def: "Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate." [EC:5.4.3.4, MetaCyc:D-LYSINE-5] synonym: "adenosylcobalamin-dependent D-lysine 5,6-aminomutase activity" EXACT [EC:5.4.3.4] synonym: "D-2,6-diaminohexanoate 5,6-aminomutase activity" EXACT [EC:5.4.3.4] synonym: "D-alpha-lysine mutase activity" EXACT [EC:5.4.3.4] xref: EC:5.4.3.4 xref: GO:0047826 xref: MetaCyc:D-LYSINE-5 is_a: CCO:F0003430 ! intramolecular transferase activity, transferring amino groups [Term] id: CCO:F0007126 name: D-lysopine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-lysine + NADP+ + H2O = L-lysine + pyruvate + NADPH." [EC:1.5.1.16, MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.16] synonym: "D(+)-lysopine dehydrogenase activity" EXACT [EC:1.5.1.16] synonym: "D-lysopine synthase activity" EXACT [EC:1.5.1.16] synonym: "lysopine dehydrogenase activity" EXACT [EC:1.5.1.16] synonym: "N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)" EXACT [EC:1.5.1.16] xref: EC:1.5.1.16 xref: GO:0047827 xref: MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007127 name: D-lyxose ketol-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-lyxose = D-xylulose." [EC:5.3.1.15, MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN] synonym: "D-lyxose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.15] synonym: "D-lyxose isomerase activity" EXACT [EC:5.3.1.15] xref: EC:5.3.1.15 xref: GO:0047828 xref: MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0007128 name: D-nopaline dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH." [EC:1.5.1.19, MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.19] synonym: "D-nopaline synthase activity" EXACT [EC:1.5.1.19] synonym: "N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.19] synonym: "nopaline dehydrogenase activity" EXACT [EC:1.5.1.19] synonym: "nopaline synthase activity" EXACT [EC:1.5.1.19] synonym: "NOS activity" EXACT [EC:1.5.1.19] xref: EC:1.5.1.19 xref: GO:0047829 xref: MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007129 name: D-octopine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH." [EC:1.5.1.11, MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.11] synonym: "D-octopine synthase activity" EXACT [EC:1.5.1.11] synonym: "N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)" EXACT [EC:1.5.1.11] synonym: "octopine dehydrogenase activity" EXACT [EC:1.5.1.11] synonym: "octopine:NAD oxidoreductase activity" EXACT [EC:1.5.1.11] synonym: "ODH activity" EXACT [EC:1.5.1.11] xref: EC:1.5.1.11 xref: GO:0047830 xref: MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007130 name: D-ornithine 4,5-aminomutase activity namespace: molecular_function def: "Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate." [EC:5.4.3.5, MetaCyc:ORNMUTST-RXN] synonym: "D-alpha-ornithine 5,4-aminomutase activity" EXACT [EC:5.4.3.5] synonym: "D-ornithine aminomutase activity" EXACT [EC:5.4.3.5] xref: EC:5.4.3.5 xref: GO:0047831 xref: MetaCyc:ORNMUTST-RXN is_a: CCO:F0003430 ! intramolecular transferase activity, transferring amino groups [Term] id: CCO:F0007131 name: D-pinitol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP+ = 5D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH." [EC:1.1.1.142, MetaCyc:D-PINITOL-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "1D-3-O-methyl-chiro-inositol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.142] synonym: "5D-5-O-methyl-chiro-inositol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.142] xref: EC:1.1.1.142 xref: GO:0047832 xref: MetaCyc:D-PINITOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007132 name: D-sorbitol dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor." [EC:1.1.99.21, MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN] synonym: "D-sorbitol dehydrogenase activity" EXACT [] synonym: "D-sorbitol:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.21] synonym: "D-sorbitol:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.21] xref: EC:1.1.99.21 xref: GO:0047833 xref: MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007133 name: D-threo-aldose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH." [EC:1.1.1.122, MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "(2S,3R)-aldose dehydrogenase activity" EXACT [EC:1.1.1.122] synonym: "D-threo-aldose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.122] synonym: "dehydrogenase, L-fucose" EXACT [EC:1.1.1.122] synonym: "L-fucose (D-arabinose) dehydrogenase activity" EXACT [EC:1.1.1.122] synonym: "L-fucose dehydrogenase activity" EXACT [EC:1.1.1.122] xref: EC:1.1.1.122 xref: GO:0047834 xref: MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007134 name: D-tryptophan N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + D-tryptophan = CoA + N-acetyl-D-tryptophan." [EC:2.3.1.34, MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase activity" EXACT [EC:2.3.1.34] synonym: "acetyl-CoA:D-tryptophan N-acetyltransferase activity" EXACT [EC:2.3.1.34] synonym: "D-tryptophan acetyltransferase activity" EXACT [EC:2.3.1.34] xref: EC:2.3.1.34 xref: GO:0047835 xref: MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0007135 name: D-tryptophan N-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: malonyl-CoA + D-tryptophan = CoA + N2-malonyl-D-tryptophan." [EC:2.3.1.112, MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN] synonym: "malonyl-CoA:D-tryptophan N-malonyltransferase activity" EXACT [EC:2.3.1.112] xref: EC:2.3.1.112 xref: GO:0047836 xref: MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN is_a: CCO:F0008003 ! N-malonyltransferase activity [Term] id: CCO:F0007136 name: D-xylose 1-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: D-xylose + NADP+ = D-xylono-1,5-lactone + NADPH." [EC:1.1.1.179, MetaCyc:D-XYLOSE-1-DEHYDROGENASE-(NADP+)-RXN] subset: gosubset_prok synonym: "D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.179] synonym: "D-xylose-NADP dehydrogenase activity" EXACT [EC:1.1.1.179] synonym: "D-xylose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.179] synonym: "D-xylose:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.179] xref: EC:1.1.1.179 xref: GO:0047837 xref: MetaCyc:D-XYLOSE-1-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007137 name: D-xylose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH." [EC:1.1.1.175, MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN] synonym: "(NAD)-linked D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] synonym: "D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] synonym: "D-xylose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.175] synonym: "NAD-D-xylose" RELATED [EC:1.1.1.175] synonym: "NAD-D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] synonym: "NAD-linked D-xylose dehydrogenase activity" EXACT [EC:1.1.1.175] xref: EC:1.1.1.175 xref: GO:0047838 xref: MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007138 name: dATP(dGTP)-DNA purinetransferase activity namespace: molecular_function def: "Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA." [EC:2.6.99.1, MetaCyc:DATP(DGTP)--DNA-PURINE-TRANSFERASE-RXN] synonym: "dATP(dGTP)--DNA purine transferase activity" EXACT [] synonym: "dATP(dGTP):depurinated-DNA purine transferase activity" EXACT [EC:2.6.99.1] xref: EC:2.6.99.1 xref: GO:0047839 xref: MetaCyc:DATP(DGTP)--DNA-PURINE-TRANSFERASE-RXN is_a: CCO:F0003342 ! transferase activity, transferring nitrogenous groups [Term] id: CCO:F0007139 name: dCTP diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate." [EC:3.6.1.12, MetaCyc:DCTP-PYROPHOSPHATASE-RXN] synonym: "dCTP nucleotidohydrolase activity" EXACT [EC:3.6.1.12] synonym: "dCTP pyrophosphatase activity" EXACT [] synonym: "dCTPase activity" EXACT [EC:3.6.1.12] synonym: "deoxy-CTPase activity" EXACT [EC:3.6.1.12] synonym: "deoxycytidine triphosphatase activity" EXACT [EC:3.6.1.12] synonym: "deoxycytidine-triphosphatase activity" EXACT [EC:3.6.1.12] xref: EC:3.6.1.12 xref: GO:0047840 xref: MetaCyc:DCTP-PYROPHOSPHATASE-RXN is_a: CCO:F0006737 ! nucleoside-triphosphate diphosphatase activity [Term] id: CCO:F0007140 name: dehydrogluconokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2-dehydro-D-gluconate = ADP + 6-phospho-2-dehydro-D-gluconate." [EC:2.7.1.13, MetaCyc:DEHYDOGLUCONOKINASE-RXN] synonym: "2-ketogluconate kinase activity" EXACT [EC:2.7.1.13] synonym: "2-ketogluconokinase activity" EXACT [EC:2.7.1.13] synonym: "ATP:2-dehydro-D-gluconate 6-phosphotransferase activity" EXACT [EC:2.7.1.13] synonym: "dehydogluconokinase activity" EXACT [] synonym: "ketogluconokinase (phosphorylating)" EXACT [EC:2.7.1.13] synonym: "ketogluconokinase activity" EXACT [EC:2.7.1.13] xref: EC:2.7.1.13 xref: GO:0047841 xref: MetaCyc:DEHYDOGLUCONOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007141 name: dehydro-L-gulonate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-dehydro-L-gulonate = L-xylulose + CO2." [EC:4.1.1.34, MetaCyc:DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN] synonym: "3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)" EXACT [EC:4.1.1.34] synonym: "3-dehydro-L-gulonate carboxy-lyase activity" EXACT [EC:4.1.1.34] synonym: "3-keto-L-gulonate decarboxylase activity" EXACT [EC:4.1.1.34] synonym: "keto-L-gulonate decarboxylase activity" EXACT [EC:4.1.1.34] xref: EC:4.1.1.34 xref: GO:0047842 xref: MetaCyc:DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007142 name: dehydrogluconate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-D-gluconate + acceptor = 2,5-didehydro-D-gluconate + reduced acceptor." [EC:1.1.99.4, MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN] synonym: "2-dehydro-D-gluconate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.4] synonym: "2-keto-D-gluconate dehydrogenase activity" EXACT [EC:1.1.99.4] synonym: "2-oxogluconate dehydrogenase activity" EXACT [EC:1.1.99.4] synonym: "alpha-ketogluconate dehydrogenase activity" EXACT [EC:1.1.99.4] synonym: "ketogluconate dehydrogenase activity" EXACT [EC:1.1.99.4] xref: EC:1.1.99.4 xref: GO:0047843 xref: MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007143 name: deoxycytidine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3." [EC:3.5.4.14, MetaCyc:DEOXYCYTIDINE-DEAMINASE-RXN] subset: gosubset_prok synonym: "deoxycytidine aminohydrolase activity" EXACT [EC:3.5.4.14] xref: EC:3.5.4.14 xref: GO:0047844 xref: MetaCyc:DEOXYCYTIDINE-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007144 name: deoxylimonate A-ring-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: deoxylimonate + H2O = deoxylimononic acid D-ring-lactone." [EC:3.1.1.46, MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN] synonym: "deoxylimonate A-ring-lactonohydrolase activity" EXACT [EC:3.1.1.46] xref: EC:3.1.1.46 xref: GO:0047845 xref: MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007145 name: deoxynucleotide 3'-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate." [EC:3.1.3.34, MetaCyc:DEOXYNUCLEOTIDE-3] synonym: "3'-deoxynucleotidase activity" EXACT [EC:3.1.3.34] synonym: "3'-deoxyribonucleotidase activity" EXACT [EC:3.1.3.34] synonym: "deoxyribonucleotide 3'-phosphohydrolase activity" EXACT [EC:3.1.3.34] xref: EC:3.1.3.34 xref: GO:0047846 xref: MetaCyc:DEOXYNUCLEOTIDE-3 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007146 name: deoxyuridine phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate." [EC:2.4.2.23, MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN] synonym: "2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.23] synonym: "deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.23] synonym: "deoxyuridine:phosphate deoxy-D-ribosyltransferase activity" EXACT [EC:2.4.2.23] xref: EC:2.4.2.23 xref: GO:0047847 xref: MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0007147 name: dephospho-[reductase kinase] kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]." [EC:2.7.11.3, MetaCyc:DEPHOSPHO-[REDUCTASE-KINASE\]-KINASE-RXN] synonym: "AMP-activated kinase activity" EXACT [EC:2.7.11.3] synonym: "AMP-activated protein kinase kinase activity" EXACT [EC:2.7.11.3] synonym: "ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity" EXACT [EC:2.7.11.3] synonym: "dephospho-reductase kinase kinase activity" EXACT [EC:2.7.11.3] synonym: "hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity" EXACT [EC:2.7.11.3] synonym: "hydroxymethylglutaryl coenzyme A reductase kinase kinase activity" EXACT [EC:2.7.11.3] synonym: "reductase kinase activity" BROAD [EC:2.7.11.3] synonym: "reductase kinase kinase activity" EXACT [EC:2.7.11.3] synonym: "STK30" RELATED [EC:2.7.11.3] xref: EC:2.7.11.3 xref: GO:0047848 xref: MetaCyc:DEPHOSPHO-[REDUCTASE-KINASE\]-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0007148 name: dextransucrase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1)." [EC:2.4.1.5, MetaCyc:DEXTRANSUCRASE-RXN] subset: gosubset_prok synonym: "CEP" RELATED [EC:2.4.1.5] synonym: "SGE" RELATED [EC:2.4.1.5] synonym: "sucrose 6-glucosyltransferase activity" EXACT [EC:2.4.1.5] synonym: "sucrose-1,6-alpha-glucan glucosyltransferase activity" EXACT [EC:2.4.1.5] synonym: "sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.5] xref: EC:2.4.1.5 xref: GO:0047849 xref: MetaCyc:DEXTRANSUCRASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007149 name: diaminopimelate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH." [EC:1.4.1.16, MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.16] synonym: "meso-alpha,epsilon-diaminopimelate dehydrogenase activity" EXACT [EC:1.4.1.16] synonym: "meso-diaminopimelate D-dehydrogenase activity" EXACT [EC:1.4.1.16] synonym: "meso-diaminopimelate dehydrogenase activity" EXACT [EC:1.4.1.16] xref: EC:1.4.1.16 xref: GO:0047850 xref: MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007150 name: dicarboxylate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + an omega-dicarboxylic acid = AMP + diphosphate + an omega-carboxyacyl-CoA." [EC:6.2.1.23, MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN] synonym: "carboxylyl-CoA synthetase activity" EXACT [EC:6.2.1.23] synonym: "omega-dicarboxylate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.23] xref: EC:6.2.1.23 xref: GO:0047851 xref: MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007151 name: diferric-transferrin reductase activity namespace: molecular_function def: "Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH." [EC:1.16.1.2, MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN] synonym: "diferric transferrin reductase activity" EXACT [EC:1.16.1.2] synonym: "NADH diferric transferrin reductase activity" EXACT [EC:1.16.1.2] synonym: "transferrin reductase activity" EXACT [EC:1.16.1.2] synonym: "transferrin[Fe(II)]2:NAD+ oxidoreductase activity" EXACT [EC:1.16.1.2] xref: EC:1.16.1.2 xref: GO:0047852 xref: MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0007152 name: difructose-anhydride synthase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose." [EC:3.2.1.134, MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN] synonym: "bis-D-fructose 2',1:2,1'-dianhydride fructohydrolase activity" EXACT [EC:3.2.1.134] synonym: "inulobiose hydrolase activity" EXACT [EC:3.2.1.134] xref: EC:3.2.1.134 xref: GO:0047853 xref: MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007153 name: diguanidinobutanase activity namespace: molecular_function def: "Catalysis of the reaction: 1,4-diguanidinobutane + H2O = agmatine + urea." [EC:3.5.3.20, MetaCyc:DIGUANIDINOBUTANASE-RXN] synonym: "1,4-diguanidinobutane amidinohydrolase activity" EXACT [EC:3.5.3.20] xref: EC:3.5.3.20 xref: GO:0047854 xref: MetaCyc:DIGUANIDINOBUTANASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007154 name: dihydrobunolol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ = (+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH." [EC:1.1.1.160, MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN] synonym: "(+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.160] synonym: "bunolol reductase activity" EXACT [EC:1.1.1.160] xref: EC:1.1.1.160 xref: GO:0047855 xref: MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007155 name: dihydrocoumarin hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: dihydrocoumarin + H2O = melilotate." [EC:3.1.1.35, MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN] subset: gosubset_prok synonym: "dihydrocoumarin lactonohydrolase activity" EXACT [EC:3.1.1.35] synonym: "dihydrocoumarin lipase activity" EXACT [] xref: EC:3.1.1.35 xref: GO:0047856 xref: MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007156 name: dihydrouracil oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 5,6-dihydrouracil + O2 = uracil + H2O2." [EC:1.3.3.7, MetaCyc:DIHYDROURACIL-OXIDASE-RXN] synonym: "5,6-dihydrouracil:oxygen oxidoreductase activity" EXACT [EC:1.3.3.7] xref: EC:1.3.3.7 xref: GO:0047857 xref: MetaCyc:DIHYDROURACIL-OXIDASE-RXN is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0007157 name: dihydroxyfumarate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: dihydroxyfumarate = tartronate semialdehyde + CO2." [EC:4.1.1.54, MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN] synonym: "dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming)" EXACT [EC:4.1.1.54] synonym: "dihydroxyfumarate carboxy-lyase activity" EXACT [EC:4.1.1.54] xref: EC:4.1.1.54 xref: GO:0047858 xref: MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007159 name: diiodophenylpyruvate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + NADH." [EC:1.1.1.96, MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN] synonym: "2-oxo acid reductase activity" EXACT [EC:1.1.1.96] synonym: "3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.96] synonym: "aromatic alpha-keto acid" RELATED [EC:1.1.1.96] synonym: "KAR" RELATED [EC:1.1.1.96] xref: EC:1.1.1.96 xref: GO:0047860 xref: MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007160 name: diiodotyrosine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 3,5-diiodo-L-tyrosine + 2-oxoglutarate = 3,5-diiodo-4-hydroxyphenylpyruvate + L-glutamate." [EC:2.6.1.24, MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN] synonym: "3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.24] synonym: "diiodotyrosine aminotransferase activity" EXACT [] synonym: "halogenated tyrosine aminotransferase activity" EXACT [EC:2.6.1.24] synonym: "halogenated tyrosine transaminase activity" EXACT [EC:2.6.1.24] xref: EC:2.6.1.24 xref: GO:0047861 xref: MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007161 name: diisopropyl-fluorophosphatase activity namespace: molecular_function def: "Catalysis of the reaction: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride." [EC:3.1.8.2, MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN] synonym: "DFPase activity" EXACT [EC:3.1.8.2] synonym: "dialkylfluorophosphatase activity" EXACT [EC:3.1.8.2] synonym: "diisopropyl phosphorofluoridate hydrolase activity" EXACT [EC:3.1.8.2] synonym: "diisopropyl-fluorophosphate fluorohydrolase activity" EXACT [EC:3.1.8.2] synonym: "diisopropylfluorophosphonate dehalogenase activity" EXACT [EC:3.1.8.2] synonym: "diisopropylphosphofluoridase activity" EXACT [EC:3.1.8.2] synonym: "isopropylphosphorofluoridase activity" EXACT [EC:3.1.8.2] synonym: "OPA anhydrase activity" EXACT [EC:3.1.8.2] synonym: "OPAA activity" EXACT [EC:3.1.8.2] synonym: "organophosphate acid anhydrase activity" EXACT [EC:3.1.8.2] synonym: "organophosphorus acid anhydrolase activity" EXACT [EC:3.1.8.2] synonym: "somanase activity" EXACT [EC:3.1.8.2] synonym: "tabunase activity" EXACT [EC:3.1.8.2] xref: EC:3.1.8.2 xref: GO:0047862 xref: MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN is_a: CCO:F0003365 ! phosphoric triester hydrolase activity [Term] id: CCO:F0007162 name: dimethylallylcistransferase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate." [EC:2.5.1.28, MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN] synonym: "dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase activity" EXACT [EC:2.5.1.28] synonym: "neryl-diphosphate synthase activity" EXACT [EC:2.5.1.28] xref: EC:2.5.1.28 xref: GO:0047863 xref: MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0007163 name: dimethylaniline-N-oxide aldolase activity namespace: molecular_function def: "Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde." [EC:4.1.2.24, MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN] subset: gosubset_prok synonym: "microsomal N-oxide dealkylase activity" EXACT [EC:4.1.2.24] synonym: "microsomal oxidase II" RELATED [EC:4.1.2.24] synonym: "N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming)" EXACT [EC:4.1.2.24] synonym: "N,N-dimethylaniline-N-oxide formaldehyde-lyase activity" EXACT [EC:4.1.2.24] xref: EC:4.1.2.24 xref: GO:0047864 xref: MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007164 name: dimethylglycine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N,N-dimethylglycine + acceptor + H2O = sarcosine + formaldehyde + reduced acceptor." [EC:1.5.99.2, MetaCyc:DIMETHYLGLYCINE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "N,N-dimethylglycine oxidase activity" EXACT [EC:1.5.99.2] synonym: "N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating)" EXACT [EC:1.5.99.2] synonym: "N,N-dimethylglycine:acceptor oxidoreductase (demethylating)" EXACT [EC:1.5.99.2] xref: EC:1.5.99.2 xref: GO:0047865 xref: MetaCyc:DIMETHYLGLYCINE-DEHYDROGENASE-RXN is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0007165 name: dimethylglycine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: N,N-dimethylglycine + H2O + O2 = sarcosine + formaldehyde + H2O2." [EC:1.5.3.10, MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN] synonym: "N,N-dimethylglycine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.10] xref: EC:1.5.3.10 xref: GO:0047866 xref: MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0007166 name: dimethylmalate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH." [EC:1.1.1.84, MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN] synonym: "(R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)" EXACT [EC:1.1.1.84] synonym: "beta,beta-dimethylmalate dehydrogenase activity" EXACT [EC:1.1.1.84] xref: EC:1.1.1.84 xref: GO:0047867 xref: MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007167 name: dimethylmaleate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O." [EC:4.2.1.85, MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN] synonym: "(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming)" EXACT [EC:4.2.1.85] synonym: "(2R,3S)-2,3-dimethylmalate hydro-lyase activity" EXACT [EC:4.2.1.85] xref: EC:4.2.1.85 xref: GO:0047868 xref: MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007168 name: dimethylpropiothetin dethiomethylase activity namespace: molecular_function def: "Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = dimethyl sulfide + acrylate." [EC:4.4.1.3, MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN] synonym: "desulfhydrase activity" EXACT [EC:4.4.1.3] synonym: "S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase (acrylate-forming)" EXACT [EC:4.4.1.3] synonym: "S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase activity" EXACT [EC:4.4.1.3] xref: EC:4.4.1.3 xref: GO:0047869 xref: MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007169 name: discadenine synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + N6-(D2-isopentenyl)-adenine = 5'-methylthioadenosine + discadenine." [EC:2.5.1.24, MetaCyc:DISCADENINE-SYNTHASE-RXN] synonym: "discadenine synthetase activity" EXACT [EC:2.5.1.24] synonym: "S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase activity" EXACT [EC:2.5.1.24] synonym: "S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferas" RELATED [EC:2.5.1.24] xref: EC:2.5.1.24 xref: GO:0047870 xref: MetaCyc:DISCADENINE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007170 name: disulfoglucosamine-6-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: N,6-O-disulfo-D-glucosamine + H2O = N-sulfo-D-glucosamine + SO4(2-) (sulfate)." [EC:3.1.6.11, MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN] synonym: "6,N-disulfoglucosamine 6-O-sulfohydrolase activity" EXACT [EC:3.1.6.11] synonym: "disulphoglucosamine-6-sulphatase activity" EXACT [] synonym: "N,6-O-disulfo-D-glucosamine 6-sulfohydrolase activity" EXACT [EC:3.1.6.11] synonym: "N-sulfoglucosamine-6-sulfatase activity" EXACT [EC:3.1.6.11] xref: EC:3.1.6.11 xref: GO:0047871 xref: MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0007171 name: dolichol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate." [EC:2.3.1.123, MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN] synonym: "acyl-CoA:dolichol acyltransferase activity" EXACT [EC:2.3.1.123] synonym: "palmitoyl-CoA:dolichol O-palmitoyltransferase activity" EXACT [EC:2.3.1.123] xref: EC:2.3.1.123 xref: GO:0047872 xref: MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0007172 name: dolichyl-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate." [EC:3.1.3.51, MetaCyc:DOLICHYL-PHOSPHATASE-RXN] synonym: "Dol-P phosphatase activity" EXACT [EC:3.1.3.51] synonym: "Dol-P-P phosphohydrolase activity" EXACT [] synonym: "dolichol monophosphatase activity" EXACT [EC:3.1.3.51] synonym: "dolichol phosphatase activity" EXACT [EC:3.1.3.51] synonym: "dolichol phosphate phosphatase activity" EXACT [EC:3.1.3.51] synonym: "dolichyl monophosphate phosphatase activity" EXACT [EC:3.1.3.51] synonym: "dolichyl phosphate phosphatase activity" EXACT [EC:3.1.3.51] synonym: "dolichyl pyrophosphate phosphatase activity" EXACT [] synonym: "dolichyl-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.51] synonym: "polyisoprenyl phosphate phosphatase activity" EXACT [EC:3.1.3.51] synonym: "polyprenylphosphate phosphatase activity" EXACT [EC:3.1.3.51] xref: EC:3.1.3.51 xref: GO:0047873 xref: MetaCyc:DOLICHYL-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007173 name: dolichyldiphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate." [EC:3.6.1.43, MetaCyc:DOLICHYLDIPHOSPHATASE-RXN] synonym: "dolichol diphosphatase activity" EXACT [EC:3.6.1.43] synonym: "dolichyl diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.43] synonym: "dolichyl pyrophosphatase activity" EXACT [EC:3.6.1.43] synonym: "dolichyl-diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.43] xref: EC:3.6.1.43 xref: GO:0047874 xref: MetaCyc:DOLICHYLDIPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0007174 name: ecdysone oxidase activity namespace: molecular_function def: "Catalysis of the reaction: ecdysone + O2 = 3-dehydroecdysone + H2O2." [EC:1.1.3.16, MetaCyc:ECDYSONE-OXIDASE-RXN] synonym: "beta-ecdysone oxidase activity" EXACT [EC:1.1.3.16] synonym: "ecdysone:oxygen 3-oxidoreductase activity" EXACT [EC:1.1.3.16] xref: EC:1.1.3.16 xref: GO:0047875 xref: MetaCyc:ECDYSONE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007175 name: endoglycosylceramidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose." [EC:3.2.1.123, MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN] subset: gosubset_prok synonym: "EGCase activity" EXACT [EC:3.2.1.123] synonym: "endo-glucosylceramidase activity" EXACT [EC:3.2.1.123] synonym: "endoglycoceramidase activity" EXACT [EC:3.2.1.123] synonym: "glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase activity" EXACT [EC:3.2.1.123] synonym: "oligoglycosylglucosylceramide glycohydrolase activity" EXACT [EC:3.2.1.123] xref: EC:3.2.1.123 xref: GO:0047876 xref: MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007176 name: ephedrine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + NADH." [EC:1.5.1.18, MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN] synonym: "(-)-ephedrine:NAD+ 2-oxidoreductase activity" EXACT [EC:1.5.1.18] xref: EC:1.5.1.18 xref: GO:0047877 xref: MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007177 name: erythritol kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + erythritol = ADP + D-erythritol 4-phosphate." [EC:2.7.1.27, MetaCyc:ERYTHRITOL-KINASE-RXN] subset: gosubset_prok synonym: "ATP:erythritol 4-phosphotransferase activity" EXACT [EC:2.7.1.27] synonym: "erythritol kinase (phosphorylating)" EXACT [EC:2.7.1.27] xref: EC:2.7.1.27 xref: GO:0047878 xref: MetaCyc:ERYTHRITOL-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007178 name: erythronolide synthase activity namespace: molecular_function def: "Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B." [EC:2.3.1.94, MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN] subset: gosubset_prok synonym: "erythronolide condensing enzyme activity" EXACT [EC:2.3.1.94] synonym: "malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing)" EXACT [EC:2.3.1.94] xref: EC:2.3.1.94 xref: GO:0047879 xref: MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007179 name: erythrulose reductase activity namespace: molecular_function def: "Catalysis of the reaction: erythritol + NADP+ = D-erythrulose + NADPH." [EC:1.1.1.162, MetaCyc:ERYTHRULOSE-REDUCTASE-RXN] synonym: "D-erythrulose reductase activity" EXACT [EC:1.1.1.162] synonym: "erythritol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.162] xref: EC:1.1.1.162 xref: GO:0047880 xref: MetaCyc:ERYTHRULOSE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007180 name: estradiol 17-alpha-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+." [EC:1.1.1.148, MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN] synonym: "17alpha-estradiol dehydrogenase activity" EXACT [EC:1.1.1.148] synonym: "17alpha-hydroxy steroid dehydrogenase activity" EXACT [EC:1.1.1.148] synonym: "17alpha-hydroxy steroid oxidoreductase activity" EXACT [EC:1.1.1.148] synonym: "17alpha-hydroxysteroid oxidoreductase activity" EXACT [EC:1.1.1.148] synonym: "17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity" EXACT [EC:1.1.1.148] synonym: "estradiol 17a-dehydrogenase activity" EXACT [] synonym: "estradiol 17alpha-dehydrogenase activity" EXACT [EC:1.1.1.148] synonym: "estradiol 17alpha-oxidoreductase activity" EXACT [EC:1.1.1.148] xref: EC:1.1.1.148 xref: GO:0047881 xref: MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007181 name: estradiol 6-beta-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: estradiol-17-beta + donor-H2 + O2 = 6-beta-hydroxyestradiol-17-beta + acceptor + H2O." [EC:1.14.99.11, MetaCyc:ESTRADIOL-6-BETA-MONOOXYGENASE-RXN] synonym: "estradiol 6-beta-hydroxylase activity" EXACT [EC:1.14.99.11] synonym: "estradiol 6b-hydroxylase activity" EXACT [] synonym: "estradiol 6b-monooxygenase activity" EXACT [] synonym: "estradiol 6beta-hydroxylase activity" EXACT [EC:1.14.99.11] synonym: "estradiol 6beta-monooxygenase activity" EXACT [EC:1.14.99.11] synonym: "estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)" EXACT [EC:1.14.99.11] xref: EC:1.14.99.11 xref: GO:0047882 xref: MetaCyc:ESTRADIOL-6-BETA-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007182 name: ethanolamine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2." [EC:1.4.3.8, MetaCyc:ETHANOLAMINE-OXIDASE-RXN] synonym: "ethanolamine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.8] xref: EC:1.4.3.8 xref: GO:0047883 xref: MetaCyc:ETHANOLAMINE-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0007183 name: FAD diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: FAD + H2O = AMP + FMN." [EC:3.6.1.18, MetaCyc:FAD-PYROPHOSPHATASE-RXN] synonym: "FAD nucleotidohydrolase activity" EXACT [EC:3.6.1.18] synonym: "FAD pyrophosphatase activity" EXACT [] synonym: "flavin adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] synonym: "flavine adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] synonym: "riboflavin adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] synonym: "riboflavine adenine dinucleotide pyrophosphatase activity" EXACT [EC:3.6.1.18] xref: EC:3.6.1.18 xref: GO:0047884 xref: MetaCyc:FAD-PYROPHOSPHATASE-RXN is_a: CCO:F0000937 ! nucleotide diphosphatase activity [Term] id: CCO:F0007184 name: farnesol 2-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol." [EC:5.2.1.9, MetaCyc:FARNESOL-2-ISOMERASE-RXN] subset: gosubset_prok synonym: "2-trans,6-trans-farnesol 2-cis-trans-isomerase activity" EXACT [EC:5.2.1.9] synonym: "farnesol isomerase activity" EXACT [EC:5.2.1.9] xref: EC:5.2.1.9 xref: GO:0047885 xref: MetaCyc:FARNESOL-2-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0007185 name: farnesol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP+ = 2-trans,6-trans-farnesal + NADPH." [EC:1.1.1.216, MetaCyc:FARNESOL-DEHYDROGENASE-RXN] synonym: "2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.216] synonym: "farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.216] synonym: "NADP-farnesol dehydrogenase activity" EXACT [EC:1.1.1.216] xref: EC:1.1.1.216 xref: GO:0047886 xref: MetaCyc:FARNESOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007186 name: farnesyl diphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + farnesyl diphosphate = ADP + farnesyl triphosphate." [EC:2.7.4.18, MetaCyc:FARNESYL-DIPHOSPHATE-KINASE-RXN] synonym: "ATP:farnesyl-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.18] synonym: "farnesyl pyrophosphate kinase activity" EXACT [EC:2.7.4.18] synonym: "farnesyl-diphosphate kinase activity" EXACT [] xref: EC:2.7.4.18 xref: GO:0047887 xref: MetaCyc:FARNESYL-DIPHOSPHATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0007187 name: fatty-acid peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: palmitate + 2 H2O2 = pentadecanal + CO2 + 3 H2O." [EC:1.11.1.3, MetaCyc:FATTY-ACID-PEROXIDASE-RXN] synonym: "fatty acid peroxidase activity" EXACT [] synonym: "hexadecanoate:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.3] synonym: "long chain fatty acid peroxidase activity" EXACT [EC:1.11.1.3] xref: EC:1.11.1.3 xref: GO:0047888 xref: MetaCyc:FATTY-ACID-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0007188 name: ferredoxin-nitrate reductase activity namespace: molecular_function def: "Catalysis of the reaction: NO2- (nitrite) + H2O + 2 oxidized ferredoxin = NO3- (nitrate) + 2 reduced ferredoxin." [EC:1.7.7.2, MetaCyc:FERREDOXIN--NITRATE-REDUCTASE-RXN] synonym: "assimilatory ferredoxin-nitrate reductase activity" EXACT [EC:1.7.7.2] synonym: "assimilatory nitrate reductase activity" BROAD [EC:1.7.7.2] synonym: "nitrate (ferredoxin) reductase activity" EXACT [EC:1.7.7.2] synonym: "nitrite:ferredoxin oxidoreductase activity" EXACT [EC:1.7.7.2] xref: EC:1.7.7.2 xref: GO:0047889 xref: MetaCyc:FERREDOXIN--NITRATE-REDUCTASE-RXN is_a: CCO:F0003259 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor [Term] id: CCO:F0007189 name: flavanone 4-reductase activity namespace: molecular_function def: "Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH." [EC:1.1.1.234, MetaCyc:FLAVANONE-4-REDUCTASE-RXN] synonym: "(2S)-flavan-4-ol:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.234] synonym: "flavonone 4-reductase activity" EXACT [] xref: EC:1.1.1.234 xref: GO:0047890 xref: MetaCyc:FLAVANONE-4-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007190 name: flavone 7-O-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone." [EC:2.4.1.81, MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "flavone 7-O-b-glucosyltransferase activity" EXACT [] synonym: "UDP-glucose-apigenin beta-glucosyltransferase activity" EXACT [EC:2.4.1.81] synonym: "UDP-glucose-luteolin beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] synonym: "UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] synonym: "UDPglucose-apigenin beta-glucosyltransferase activity" EXACT [EC:2.4.1.81] synonym: "UDPglucose-luteolin beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] synonym: "UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.81] synonym: "uridine diphosphoglucose-apigenin 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.81] synonym: "uridine diphosphoglucose-luteolin glucosyltransferase activity" EXACT [EC:2.4.1.81] xref: EC:2.4.1.81 xref: GO:0047891 xref: MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007191 name: flavone apiosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone." [EC:2.4.2.25, MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN] synonym: "UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity" EXACT [EC:2.4.2.25] synonym: "UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity" EXACT [EC:2.4.2.25] synonym: "uridine diphosphoapiose-flavone apiosyltransferase activity" EXACT [EC:2.4.2.25] xref: EC:2.4.2.25 xref: GO:0047892 xref: MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0007192 name: flavonol 3-O-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside." [EC:2.4.1.91, MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN] synonym: "GTI" RELATED [EC:2.4.1.91] synonym: "UDP-glucose flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] synonym: "UDP-glucose:flavonol 3-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.91] synonym: "UDP-glucose:flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] synonym: "UDPG:flavonoid-3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] synonym: "UDPglucose:flavonol 3-O-D-glucosyltransferase activity" EXACT [EC:2.4.1.91] synonym: "uridine diphosphoglucose-flavonol 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.91] xref: EC:2.4.1.91 xref: GO:0047893 xref: MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007193 name: flavonol 3-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + quercetin = adenosine 3',5'-bisphosphate + quercetin 3-sulfate." [EC:2.8.2.25, MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:quercetin 3-sulfotransferase activity" EXACT [EC:2.8.2.25] synonym: "flavonol 3-sulphotransferase activity" EXACT [] xref: EC:2.8.2.25 xref: GO:0047894 xref: MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007194 name: formaldehyde dismutase activity namespace: molecular_function def: "Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate." [EC:1.2.99.4, MetaCyc:FORMALDEHYDE-DISMUTASE-RXN] synonym: "aldehyde dismutase activity" EXACT [EC:1.2.99.4] synonym: "cannizzanase activity" EXACT [EC:1.2.99.4] synonym: "formaldehyde:formaldehyde oxidoreductase activity" EXACT [EC:1.2.99.4] xref: EC:1.2.99.4 xref: GO:0047895 xref: MetaCyc:FORMALDEHYDE-DISMUTASE-RXN is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0007195 name: formaldehyde transketolase activity namespace: molecular_function def: "Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone." [EC:2.2.1.3, MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN] synonym: "D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase activity" EXACT [EC:2.2.1.3] synonym: "DHAS activity" EXACT [EC:2.2.1.3] synonym: "dihydroxyacetone synthase activity" EXACT [EC:2.2.1.3] synonym: "glycerone synthase activity" EXACT [EC:2.2.1.3] xref: EC:2.2.1.3 xref: GO:0047896 xref: MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0007196 name: formate-dihydrofolate ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + formate + dihydrofolate = ADP + phosphate + 10-formyldihydrofolate." [EC:6.3.4.17, MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN] synonym: "dihydrofolate formyltransferase activity" EXACT [EC:6.3.4.17] synonym: "formate:dihydrofolate ligase (ADP-forming)" EXACT [EC:6.3.4.17] synonym: "formyl dihydrofolate synthase activity" EXACT [EC:6.3.4.17] xref: EC:6.3.4.17 xref: GO:0047897 xref: MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0007197 name: formate dehydrogenase (cytochrome) activity namespace: molecular_function def: "Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1." [EC:1.2.2.1, MetaCyc:FORMATE-DEHYDROGENASE-(CYTOCHROME)-RXN] synonym: "formate:cytochrome b1 oxidoreductase activity" EXACT [EC:1.2.2.1] synonym: "formate:ferricytochrome-b1 oxidoreductase activity" EXACT [EC:1.2.2.1] xref: EC:1.2.2.1 xref: GO:0047898 xref: MetaCyc:FORMATE-DEHYDROGENASE-(CYTOCHROME)-RXN is_a: CCO:F0003224 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor [Term] id: CCO:F0007198 name: formate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: formate + NADP+ = CO2 + NADPH." [EC:1.2.1.43, MetaCyc:FORMATE-DEHYDROGENASE-(NADP+)-RXN] subset: gosubset_prok synonym: "formate:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.43] synonym: "NADP-dependent formate dehydrogenase activity" EXACT [EC:1.2.1.43] xref: EC:1.2.1.43 xref: GO:0047899 xref: MetaCyc:FORMATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007199 name: formate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + formate = ADP + formyl phosphate." [EC:2.7.2.6, MetaCyc:FORMATE-KINASE-RXN] synonym: "ATP:formate phosphotransferase activity" EXACT [EC:2.7.2.6] xref: EC:2.7.2.6 xref: GO:0047900 xref: MetaCyc:FORMATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0007200 name: formyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: formyl-CoA + H2O = CoA + formate." [EC:3.1.2.10, MetaCyc:FORMYL-COA-HYDROLASE-RXN] synonym: "formyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.10] xref: EC:3.1.2.10 xref: GO:0047901 xref: MetaCyc:FORMYL-COA-HYDROLASE-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0007201 name: formylaspartate deformylase activity namespace: molecular_function def: "Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate." [EC:3.5.1.8, MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN] synonym: "formylaspartic formylase (formylase I, formylase II)" EXACT [EC:3.5.1.8] synonym: "N-formyl-L-aspartate amidohydrolase activity" EXACT [EC:3.5.1.8] xref: EC:3.5.1.8 xref: GO:0047902 xref: MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007202 name: fructose 5-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH." [EC:1.1.1.124, MetaCyc:FRUCTOSE-5-DEHYDROGENASE-(NADP+)-RXN] subset: gosubset_prok synonym: "5-keto-D-fructose reductase (NADP+)" EXACT [EC:1.1.1.124] synonym: "5-ketofructose reductase (NADP(+)) activity" EXACT [EC:1.1.1.124] synonym: "5-ketofructose reductase (NADP)" EXACT [EC:1.1.1.124] synonym: "5-ketofructose reductase (NADP+) activity" EXACT [EC:1.1.1.124] synonym: "D-(-)fructose:(NADP+) 5-oxidoreductase activity" EXACT [EC:1.1.1.124] synonym: "D-fructose:NADP+ 5-oxidoreductase activity" EXACT [EC:1.1.1.124] synonym: "fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.124] xref: EC:1.1.1.124 xref: GO:0047903 xref: MetaCyc:FRUCTOSE-5-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007203 name: fructose 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-fructose + acceptor = 5-dehydro-D-fructose + reduced acceptor." [EC:1.1.99.11, MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN] synonym: "D-fructose dehydrogenase activity" EXACT [EC:1.1.99.11] synonym: "D-fructose:(acceptor) 5-oxidoreductase activity" EXACT [EC:1.1.99.11] synonym: "D-fructose:acceptor 5-oxidoreductase activity" EXACT [EC:1.1.99.11] synonym: "fructose 5-dehydrogenase (acceptor)" EXACT [EC:1.1.99.11] xref: EC:1.1.99.11 xref: GO:0047904 xref: MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007204 name: fructose-6-phosphate phosphoketolase activity namespace: molecular_function def: "Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O." [EC:4.1.2.22, MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN] subset: gosubset_prok synonym: "D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)" EXACT [EC:4.1.2.22] synonym: "D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-acetylating) activity" EXACT [EC:4.1.2.22] xref: EC:4.1.2.22 xref: GO:0047905 xref: MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007205 name: fucosterol-epoxide lyase activity namespace: molecular_function def: "Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = desmosterol + acetaldehyde." [EC:4.1.2.33, MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN] synonym: "(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)" EXACT [EC:4.1.2.33] synonym: "(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase activity" EXACT [EC:4.1.2.33] xref: EC:4.1.2.33 xref: GO:0047906 xref: MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007206 name: furylfuramide isomerase activity namespace: molecular_function def: "Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide." [EC:5.2.1.6, MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN] synonym: "2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity" EXACT [EC:5.2.1.6] xref: EC:5.2.1.6 xref: GO:0047907 xref: MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0007207 name: fusarinine-C ornithinesterase activity namespace: molecular_function def: "Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol." [EC:3.1.1.48, MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN] synonym: "5-N-acyl-L-ornithine-ester hydrolase activity" EXACT [EC:3.1.1.48] synonym: "N5-acyl-L-ornithine-ester hydrolase activity" EXACT [EC:3.1.1.48] synonym: "ornithine esterase activity" EXACT [EC:3.1.1.48] xref: EC:3.1.1.48 xref: GO:0047908 xref: MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007208 name: galactolipid O-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol." [EC:2.3.1.134, MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN] synonym: "galactolipid:galactolipid acyltransferase activity" EXACT [EC:2.3.1.134] synonym: "mono-beta-D-galactosyldiacylglycerol:mono-beta-D-galactosyldiacylglycerol acyltransferase activity" EXACT [EC:2.3.1.134] xref: EC:2.3.1.134 xref: GO:0047909 xref: MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0007209 name: galactose 1-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH." [EC:1.1.1.120, MetaCyc:GALACTOSE-1-DEHYDROGENASE-(NADP+)-RXN] synonym: "D-galactose dehydrogenase (NADP+)" EXACT [EC:1.1.1.120] synonym: "D-galactose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.120] xref: EC:1.1.1.120 xref: GO:0047910 xref: MetaCyc:GALACTOSE-1-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007210 name: galacturan 1,4-alpha-galacturonidase activity namespace: molecular_function def: "Catalysis of the reaction: 1,4-alpha-D-galacturonide(n) + H2O = 1,4-alpha-D-galacturonide(n-1) + D-galacturonate." [EC:3.2.1.67, MetaCyc:GALACTURAN-1] synonym: "exo-D-galacturonanase activity" EXACT [EC:3.2.1.67] synonym: "exo-D-galacturonase activity" EXACT [] synonym: "exo-polygalacturonase activity" EXACT [] synonym: "exopoly-D-galacturonase activity" EXACT [] synonym: "exopolygalacturonase activity" EXACT [EC:3.2.1.67] synonym: "galacturan 1,4-a-galacturonidase activity" EXACT [] synonym: "poly(1,4-alpha-D-galacturonide) galacturonohydrolase activity" EXACT [EC:3.2.1.67] synonym: "poly(galacturonate) hydrolase activity" EXACT [EC:3.2.1.67] xref: EC:3.2.1.67 xref: GO:0047911 xref: MetaCyc:GALACTURAN-1 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007211 name: galacturonokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-galacturonate = ADP + 1-phospho-alpha-D-galacturonate." [EC:2.7.1.44, MetaCyc:GALACTURONOKINASE-RXN] synonym: "ATP:D-galacturonate 1-phosphotransferase activity" EXACT [EC:2.7.1.44] synonym: "galacturonokinase (phosphorylating) D-galacturonic acid kinase activity" EXACT [EC:2.7.1.44] xref: EC:2.7.1.44 xref: GO:0047912 xref: MetaCyc:GALACTURONOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007212 name: gallate 1-beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + gallate = UDP + 1-galloyl-beta-D-glucose." [EC:2.4.1.136, MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "gallate 1-b-glucosyltransferase activity" EXACT [] synonym: "UDP-glucose-vanillate 1-glucosyltransferase activity" EXACT [EC:2.4.1.136] synonym: "UDP-glucose:gallate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.136] synonym: "UDPglucose-vanillate 1-glucosyltransferase activity" EXACT [EC:2.4.1.136] synonym: "UDPglucose:gallate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.136] synonym: "UDPglucose:gallate glucosyltransferase activity" EXACT [EC:2.4.1.136] synonym: "UDPglucose:vanillate 1-O-glucosyltransferase activity" EXACT [EC:2.4.1.136] xref: EC:2.4.1.136 xref: GO:0047913 xref: MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007213 name: gamma-glutamylhistamine synthase activity namespace: molecular_function def: "Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown." [EC:6.3.2.18, MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN] synonym: "g-glutamylhistamine synthase activity" EXACT [] synonym: "gamma-GHA synthetase activity" EXACT [EC:6.3.2.18] synonym: "gamma-glutaminylhistamine synthetase activity" EXACT [EC:6.3.2.18] synonym: "L-glutamate:histamine ligase activity" EXACT [EC:6.3.2.18] xref: EC:6.3.2.18 xref: GO:0047914 xref: MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0007214 name: ganglioside galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine." [EC:2.4.1.62, MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN] synonym: "GM1-synthase activity" EXACT [EC:2.4.1.62] synonym: "UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "UDP-galactose-GM2 galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "UDP-galactose-GM2 ganglioside galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "UDPgalactose-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "uridine diphosphate D-galactose:glycolipid galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "uridine diphosphogalactose-ceramide galactosyltransferase activity" EXACT [EC:2.4.1.62] synonym: "uridine diphosphogalactose-GM2 galactosyltransferase activity" EXACT [EC:2.4.1.62] xref: EC:2.4.1.62 xref: GO:0047915 xref: MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0007215 name: GDP-6-deoxy-D-talose 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+." [EC:1.1.1.135, MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN] synonym: "GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase activity" EXACT [EC:1.1.1.135] synonym: "guanosine diphospho-6-deoxy-D-talose dehydrogenase activity" EXACT [EC:1.1.1.135] xref: EC:1.1.1.135 xref: GO:0047916 xref: MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007216 name: GDP-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-glucose + H2O = D-glucose + GDP." [EC:3.2.1.42, MetaCyc:GDP-GLUCOSIDASE-RXN] synonym: "GDP-glucose glucohydrolase activity" EXACT [EC:3.2.1.42] synonym: "GDPglucose glucohydrolase activity" EXACT [EC:3.2.1.42] synonym: "GDPglucosidase activity" EXACT [EC:3.2.1.42] synonym: "guanosine diphosphate D-glucose glucohydrolase activity" EXACT [EC:3.2.1.42] synonym: "guanosine diphosphoglucosidase activity" EXACT [EC:3.2.1.42] xref: EC:3.2.1.42 xref: GO:0047917 xref: MetaCyc:GDP-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007217 name: GDP-mannose 3,5-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-mannose = GDP-L-galactose." [EC:5.1.3.18] synonym: "GDP-D-mannose:GDP-L-galactose epimerase activity" EXACT [EC:5.1.3.18] synonym: "GDPmannose 3,5-epimerase activity" EXACT [EC:5.1.3.18] synonym: "guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity" EXACT [EC:5.1.3.18] xref: EC:5.1.3.18 xref: GO:0047918 xref: MetaCyc:RXN-1882 is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007218 name: GDP-mannose 6-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-D-mannose + 2 NAD+ + H2O = GDP-D-mannuronate + 2 NADH." [EC:1.1.1.132, MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "GDP mannose dehydrogenase activity" EXACT [EC:1.1.1.132] synonym: "GDP-D-mannose:NAD+ 6-oxidoreductase activity" EXACT [EC:1.1.1.132] synonym: "GDPmannose 6-dehydrogenase activity" EXACT [EC:1.1.1.132] synonym: "guanosine diphospho-D-mannose dehydrogenase activity" EXACT [EC:1.1.1.132] synonym: "guanosine diphosphomannose dehydrogenase activity" EXACT [EC:1.1.1.132] xref: EC:1.1.1.132 xref: GO:0047919 xref: MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007219 name: geissoschizine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: geissoschizine + NADP+ = 4,21-dehydrogeissoschizine + NADPH." [EC:1.3.1.36, MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN] synonym: "geissoschizine:NADP+ 4,21-oxidoreductase activity" EXACT [EC:1.3.1.36] xref: EC:1.3.1.36 xref: GO:0047920 xref: MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007220 name: aminoglycoside 2'-N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 2'-N-acetylaminoglycoside. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring." [GOC:cb] synonym: "acetyl-CoA:gentamicin-C1a N2'-acetyltransferase activity" NARROW [EC:2.3.1.59] synonym: "acetyl-CoA:gentamycin-C1a N2'-acetyltransferase activity" NARROW [EC:2.3.1.59] synonym: "gentamicin 2'-N-acetyltransferase activity" NARROW [] synonym: "gentamicin acetyltransferase II activity" NARROW [EC:2.3.1.59] synonym: "gentamycin 2'-N-acetyltransferase activity" NARROW [] synonym: "gentamycin acetyltransferase II" RELATED [EC:2.3.1.59] xref: EC:2.3.1.59 xref: GO:0047921 xref: MetaCyc:GENTAMICIN-2 is_a: CCO:F0005513 ! aminoglycoside N-acetyltransferase activity [Term] id: CCO:F0007221 name: gentisate 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-dihydroxybenzoate + O2 = maleylpyruvate." [EC:1.13.11.4, MetaCyc:GENTISATE-1] subset: gosubset_prok synonym: "2,5-dihydroxybenzoate dioxygenase activity" EXACT [EC:1.13.11.4] synonym: "gentisate dioxygenase activity" EXACT [EC:1.13.11.4] synonym: "gentisate oxygenase activity" EXACT [EC:1.13.11.4] synonym: "gentisate:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.4] synonym: "gentisic acid oxidase activity" EXACT [EC:1.13.11.4] xref: EC:1.13.11.4 xref: GO:0047922 xref: MetaCyc:GENTISATE-1 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007222 name: gentisate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2,5-dihydroxybenzoate = hydroquinone + CO2." [EC:4.1.1.62, MetaCyc:GENTISATE-DECARBOXYLASE-RXN] synonym: "2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming)" EXACT [EC:4.1.1.62] synonym: "2,5-dihydroxybenzoate decarboxylase activity" EXACT [EC:4.1.1.62] synonym: "gentisate carboxy-lyase activity" EXACT [EC:4.1.1.62] xref: EC:4.1.1.62 xref: GO:0047923 xref: MetaCyc:GENTISATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007223 name: geraniol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH." [EC:1.1.1.183, MetaCyc:GERANIOL-DEHYDROGENASE-RXN] synonym: "geraniol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.183] xref: EC:1.1.1.183 xref: GO:0047924 xref: MetaCyc:GERANIOL-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0734 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007224 name: geranoyl-CoA carboxylase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + geranoyl-CoA + HCO3- = ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA." [EC:6.4.1.5, MetaCyc:GERANOYL-COA-CARBOXYLASE-RXN] synonym: "geranoyl coenzyme A carboxylase activity" EXACT [EC:6.4.1.5] synonym: "geranoyl-CoA:carbon-dioxide ligase (ADP-forming)" EXACT [EC:6.4.1.5] synonym: "geranyl-CoA carboxylase activity" EXACT [EC:6.4.1.5] xref: EC:6.4.1.5 xref: GO:0047925 xref: MetaCyc:GERANOYL-COA-CARBOXYLASE-RXN xref: UM-BBD_enzymeID:e0721 is_a: CCO:F0003144 ! CoA carboxylase activity [Term] id: CCO:F0007225 name: geranyl-diphosphate cyclase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate = (+)-bornyl diphosphate." [EC:5.5.1.8, MetaCyc:GERANYL-DIPHOSPHATE-CYCLASE-RXN] synonym: "(+)-bornyl-diphosphate lyase (decyclizing)" EXACT [EC:5.5.1.8] synonym: "(+)-bornylpyrophosphate cyclase activity" EXACT [EC:5.5.1.8] synonym: "bornyl diphosphate synthase activity" EXACT [EC:5.5.1.8] synonym: "bornyl pyrophosphate synthase activity" EXACT [EC:5.5.1.8] synonym: "bornyl pyrophosphate synthetase activity" EXACT [EC:5.5.1.8] xref: EC:5.5.1.8 xref: GO:0047926 xref: MetaCyc:GERANYL-DIPHOSPHATE-CYCLASE-RXN is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0007226 name: gibberellin-44 dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2." [EC:1.14.11.12, MetaCyc:GIBBERELLIN-44-DIOXYGENASE-RXN] synonym: "(gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.12] synonym: "(gibberellin-44),2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.12] synonym: "gibberellin A44 oxidase activity" EXACT [EC:1.14.11.12] synonym: "oxygenase, gibberellin A44 oxidase activity" EXACT [EC:1.14.11.12] xref: EC:1.14.11.12 xref: GO:0047927 xref: MetaCyc:GIBBERELLIN-44-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0007227 name: gibberellin beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside." [EC:2.4.1.176, MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "gibberellin b-glucosyltransferase activity" EXACT [] synonym: "UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.176] synonym: "UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.176] synonym: "uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase activity" EXACT [EC:2.4.1.176] synonym: "uridine diphosphoglucose-gibberellate 7-glucosyltransferase activity" EXACT [EC:2.4.1.176] xref: EC:2.4.1.176 xref: GO:0047928 xref: MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007228 name: gluconate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O." [EC:4.2.1.39, MetaCyc:GLUCONATE-DEHYDRATASE-RXN] subset: gosubset_prok synonym: "D-gluconate dehydratase activity" EXACT [EC:4.2.1.39] synonym: "D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)" EXACT [EC:4.2.1.39] synonym: "D-gluconate hydro-lyase activity" EXACT [EC:4.2.1.39] xref: EC:4.2.1.39 xref: GO:0047929 xref: MetaCyc:GLUCONATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007229 name: glucosaminate ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3." [EC:4.3.1.9, MetaCyc:GLUCOSAMINATE-AMMONIA-LYASE-RXN] comment: Note that this function was EC:4.3.1.21. synonym: "2-amino-2-deoxy-D-gluconate ammonia-lyase activity" EXACT [EC:4.3.1.9] synonym: "2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating) activity" EXACT [EC:4.3.1.9] synonym: "acetylenemonocarboxylic acid hydrase activity" EXACT [EC:4.3.1.9] synonym: "aminodeoxygluconate ammonia-lyase activity" EXACT [] synonym: "aminodeoxygluconate dehydratase activity" EXACT [] synonym: "D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)" EXACT [EC:4.3.1.9] synonym: "D-glucosaminate ammonia-lyase activity" EXACT [EC:4.3.1.9] synonym: "D-glucosaminate dehydratase activity" EXACT [EC:4.3.1.9] synonym: "D-glucosaminic acid dehydrase activity" EXACT [EC:4.3.1.9] synonym: "glucosaminic dehydrase activity" EXACT [EC:4.3.1.9] xref: EC:4.3.1.9 xref: GO:0047930 xref: GO:0050443 xref: MetaCyc:4.3.1.21-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0007230 name: glucosamine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate." [EC:2.7.1.8, MetaCyc:GLUCOSAMINE-KINASE-RXN] synonym: "aminodeoxyglucose kinase activity" EXACT [EC:2.7.1.8] synonym: "ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase activity" EXACT [EC:2.7.1.8] synonym: "ATP:D-glucosamine phosphotransferase activity" EXACT [EC:2.7.1.8] synonym: "glucosamine kinase (phosphorylating)" EXACT [EC:2.7.1.8] xref: EC:2.7.1.8 xref: GO:0047931 xref: MetaCyc:GLUCOSAMINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007231 name: glucosamine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + D-glucosamine = CoA + N-acetyl-D-glucosamine." [EC:2.3.1.3, MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:D-glucosamine N-acetyltransferase activity" EXACT [EC:2.3.1.3] synonym: "glucosamine acetylase activity" EXACT [EC:2.3.1.3] synonym: "glucosamine acetyltransferase activity" EXACT [EC:2.3.1.3] xref: EC:2.3.1.3 xref: GO:0047932 xref: MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0007232 name: glucose-1,6-bisphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate = 3-phospho-D-glycerate + D-glucose 1,6-bisphosphate." [EC:2.7.1.106, MetaCyc:GLUCOSE-1] synonym: "3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.106] synonym: "3-phospho-D-glyceroyl-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.106] synonym: "glucose 1,6-diphosphate synthase activity" EXACT [EC:2.7.1.106] synonym: "glucose-1,6-bisphosphate synthetase activity" EXACT [EC:2.7.1.106] xref: EC:2.7.1.106 xref: GO:0047933 xref: MetaCyc:GLUCOSE-1 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007233 name: glucose 1-dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH." [EC:1.1.1.118, MetaCyc:GLUCOSE-1-DEHYDROGENASE-(NAD+)-RXN] synonym: "D-aldohexose dehydrogenase activity" EXACT [EC:1.1.1.118] synonym: "D-glucose:NAD oxidoreductase activity" EXACT [EC:1.1.1.118] synonym: "D-glucose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.118] xref: EC:1.1.1.118 xref: GO:0047934 xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-(NAD+)-RXN is_a: CCO:F0007235 ! glucose 1-dehydrogenase activity [Term] id: CCO:F0007234 name: glucose 1-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,4-lactone + NADPH." [EC:1.1.1.119, MetaCyc:GLUCOSE-1-DEHYDROGENASE-(NADP+)-RXN] synonym: "D-glucose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.119] synonym: "NADP-dependent glucose dehydrogenase activity" EXACT [EC:1.1.1.119] synonym: "NADP-linked aldohexose dehydrogenase activity" EXACT [EC:1.1.1.119] synonym: "nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity" EXACT [EC:1.1.1.119] xref: EC:1.1.1.119 xref: GO:0047935 xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0007235 ! glucose 1-dehydrogenase activity [Term] id: CCO:F0007235 name: glucose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H." [EC:1.1.1.47, MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "beta-D-glucose:NAD(P)+ 1-oxidoreductase activity" EXACT [EC:1.1.1.47] synonym: "D-glucose dehydrogenase (NAD(P))" EXACT [EC:1.1.1.47] synonym: "hexose phosphate dehydrogenase activity" EXACT [EC:1.1.1.47] xref: EC:1.1.1.47 xref: GO:0047936 xref: MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007236 name: glucose-1-phosphate phosphodismutase activity namespace: molecular_function def: "Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate." [EC:2.7.1.41, MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN] subset: gosubset_prok synonym: "D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.41] synonym: "glucose 1-phosphate transphosphorylase activity" EXACT [EC:2.7.1.41] synonym: "phosphodismutase activity" EXACT [EC:2.7.1.41] xref: EC:2.7.1.41 xref: GO:0047937 xref: MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007237 name: glucose-6-phosphate 1-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate." [EC:5.1.3.15, MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN] synonym: "D-glucose-6-phosphate 1-epimerase activity" EXACT [EC:5.1.3.15] synonym: "glucose-6 phosphate 1-epimerase activity" EXACT [] xref: EC:5.1.3.15 xref: GO:0047938 xref: MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007238 name: L-glucuronate reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-gulonate + NADP+ = D-glucuronate + NADPH." [EC:1.1.1.19, MetaCyc:GLUCURONATE-REDUCTASE-RXN] synonym: "aldehyde reductase II activity" RELATED [EC:1.1.1.19] synonym: "D-glucuronate dehydrogenase activity" EXACT [EC:1.1.1.19] synonym: "D-glucuronate reductase activity" NARROW [EC:1.1.1.19] synonym: "glucuronate dehydrogenase activity" EXACT [EC:1.1.1.19] synonym: "glucuronate reductase activity" EXACT [] synonym: "NADP-L-gulonate dehydrogenase activity" EXACT [EC:1.1.1.19] synonym: "TPN-L-gulonate dehydrogenase activity" EXACT [EC:1.1.1.19] xref: EC:1.1.1.19 xref: GO:0047939 xref: MetaCyc:GLUCURONATE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007239 name: glucuronokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-glucuronate = ADP + 1-phospho-alpha-D-glucuronate." [EC:2.7.1.43, MetaCyc:GLUCURONOKINASE-RXN] synonym: "ATP:D-glucuronate 1-phosphotransferase activity" EXACT [EC:2.7.1.43] synonym: "glucurono-glucuronokinase activity" EXACT [EC:2.7.1.43] synonym: "glucuronokinase (phosphorylating)" EXACT [EC:2.7.1.43] xref: EC:2.7.1.43 xref: GO:0047940 xref: MetaCyc:GLUCURONOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007240 name: glucuronolactone reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + NADPH." [EC:1.1.1.20, MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN] subset: gosubset_prok xref: EC:1.1.1.20 xref: GO:0047941 xref: MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007241 name: glutamate-ethylamine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate + ethylamine = ADP + phosphate + N5-ethyl-L-glutamine." [EC:6.3.1.6, MetaCyc:GLUTAMATE--ETHYLAMINE-LIGASE-RXN] synonym: "L-glutamate:ethylamine ligase (ADP-forming)" EXACT [EC:6.3.1.6] synonym: "N(5)-ethyl-L-glutamine synthetase activity" EXACT [EC:6.3.1.6] synonym: "N5-ethyl-L-glutamine synthetase activity" EXACT [EC:6.3.1.6] synonym: "N5-ethylglutamine synthetase activity" EXACT [EC:6.3.1.6] synonym: "theanine synthetase activity" EXACT [EC:6.3.1.6] xref: EC:6.3.1.6 xref: GO:0047942 xref: MetaCyc:GLUTAMATE--ETHYLAMINE-LIGASE-RXN is_a: CCO:F0003439 ! acid-ammonia (or amide) ligase activity [Term] id: CCO:F0007242 name: glutamate-methylamine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate + methylamine = ADP + phosphate + N5-methyl-L-glutamine." [EC:6.3.4.12, MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN] synonym: "gamma-glutamylmethylamide synthetase activity" EXACT [EC:6.3.4.12] synonym: "L-glutamate:methylamine ligase (ADP-forming)" EXACT [EC:6.3.4.12] xref: EC:6.3.4.12 xref: GO:0047943 xref: MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0007243 name: glutamate 1-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-glutamate = ADP + alpha-L-glutamyl phosphate." [EC:2.7.2.13, MetaCyc:GLUTAMATE-1-KINASE-RXN] synonym: "ATP:L-glutamate 1-phosphotransferase activity" EXACT [EC:2.7.2.13] xref: EC:2.7.2.13 xref: GO:0047944 xref: MetaCyc:GLUTAMATE-1-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0007244 name: glutamine-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine." [EC:2.6.1.15, MetaCyc:GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN] subset: gosubset_prok synonym: "gamma-glutaminyltransferase activity" EXACT [EC:2.6.1.15] synonym: "glutaminase II activity" EXACT [EC:2.6.1.15] synonym: "glutamine transaminase activity" EXACT [EC:2.6.1.15] synonym: "glutamine transaminase L activity" EXACT [EC:2.6.1.15] synonym: "glutamine--oxo-acid transaminase activity" EXACT [EC:2.6.1.15] synonym: "glutamine--pyruvate aminotransferase activity" EXACT [] synonym: "glutamine-alpha-keto acid transamidase activity" EXACT [EC:2.6.1.15] synonym: "glutamine-alpha-keto acid transaminase activity" EXACT [EC:2.6.1.15] synonym: "glutamine-keto acid aminotransferase activity" EXACT [EC:2.6.1.15] synonym: "glutamine-oxo acid aminotransferase activity" EXACT [EC:2.6.1.15] synonym: "L-glutamine transaminase L" RELATED [EC:2.6.1.15] synonym: "L-glutamine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.15] xref: EC:2.6.1.15 xref: GO:0047945 xref: MetaCyc:GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007245 name: glutamine N-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine." [EC:2.3.1.68, MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN] synonym: "acyl-CoA:L-glutamine N-acyltransferase activity" EXACT [EC:2.3.1.68] xref: EC:2.3.1.68 xref: GO:0047946 xref: MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0007246 name: glutamine N-phenylacetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine." [EC:2.3.1.14, MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN] synonym: "glutamine phenylacetyltransferase activity" EXACT [EC:2.3.1.14] synonym: "phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase activity" EXACT [EC:2.3.1.14] synonym: "phenylacetyl-CoA:L-glutamine N-acetyltransferase activity" EXACT [EC:2.3.1.14] xref: EC:2.3.1.14 xref: GO:0047947 xref: MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007247 name: glutarate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + glutarate + CoA = ADP + phosphate + glutaryl-CoA." [EC:6.2.1.6, MetaCyc:GLUTARATE--COA-LIGASE-RXN] synonym: "glutarate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.6] synonym: "glutaryl coenzyme A synthetase activity" EXACT [EC:6.2.1.6] synonym: "glutaryl-CoA synthetase activity" EXACT [EC:6.2.1.6] xref: EC:6.2.1.6 xref: GO:0047948 xref: MetaCyc:GLUTARATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007248 name: glutarate-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH." [EC:1.2.1.20, MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN] synonym: "glutarate semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.20] synonym: "glutarate-semialdehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.20] xref: EC:1.2.1.20 xref: GO:0047949 xref: MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007249 name: glutathione oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 glutathione + O2 = oxidized glutathione + H2O2." [EC:1.8.3.3, MetaCyc:GLUTATHIONE-OXIDASE-RXN] synonym: "glutathione:oxygen oxidoreductase activity" EXACT [EC:1.8.3.3] xref: EC:1.8.3.3 xref: GO:0047950 xref: MetaCyc:GLUTATHIONE-OXIDASE-RXN is_a: CCO:F0003263 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor [Term] id: CCO:F0007250 name: glutathione thiolesterase activity namespace: molecular_function def: "Catalysis of the reaction: S-acylglutathione + H2O = glutathione + a carboxylate." [EC:3.1.2.7, MetaCyc:GLUTATHIONE-THIOESTERASE-RXN] synonym: "citryl-glutathione thioesterhydrolase activity" EXACT [EC:3.1.2.7] synonym: "glutathione thioesterase activity" EXACT [] synonym: "S-acylglutathione hydrolase activity" EXACT [EC:3.1.2.7] xref: EC:3.1.2.7 xref: GO:0047951 xref: MetaCyc:GLUTATHIONE-THIOESTERASE-RXN is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0007251 name: glycerol-3-phosphate dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+." [EC:1.1.1.94, MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN] subset: gosubset_prok synonym: "glycerol 3-phosphate dehydrogenase (NAD(P)) activity" EXACT [EC:1.1.1.94] synonym: "glycerol 3-phosphate dehydrogenase (NADP) activity" EXACT [EC:1.1.1.94] synonym: "glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) activity" EXACT [EC:1.1.1.94] synonym: "glycerol-3-phosphate dehydrogenase (NAD(P)+) activity" EXACT [] synonym: "L-glycerol-3-phosphate:NAD(P) oxidoreductase activity" EXACT [EC:1.1.1.94] synonym: "sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.94] xref: EC:1.1.1.94 xref: GO:0047952 xref: MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007252 name: glycerol 2-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: glycerol + NADP+ = glycerone + NADPH." [EC:1.1.1.156, MetaCyc:GLYCEROL-2-DEHYDROGENASE-(NADP+)-RXN] synonym: "DHA oxidoreductase activity" EXACT [EC:1.1.1.156] synonym: "dihydroxyacetone (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.1.1.156] synonym: "dihydroxyacetone reductase (NADPH)" EXACT [EC:1.1.1.156] synonym: "dihydroxyacetone reductase activity" EXACT [EC:1.1.1.156] synonym: "glycerol:NADP+ 2-oxidoreductase (glycerone-forming)" EXACT [EC:1.1.1.156] xref: EC:1.1.1.156 xref: GO:0047953 xref: MetaCyc:GLYCEROL-2-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007253 name: glycerol-2-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: glycerol 2-phosphate + H2O = glycerol + phosphate." [EC:3.1.3.19, MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN] synonym: "2-glycerophosphatase activity" EXACT [EC:3.1.3.19] synonym: "beta-glycerophosphatase activity" EXACT [EC:3.1.3.19] synonym: "beta-glycerophosphate phosphatase activity" EXACT [EC:3.1.3.19] synonym: "glycerol-2-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.19] xref: EC:3.1.3.19 xref: GO:0047954 xref: MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007254 name: glycerol dehydrogenase (acceptor) activity namespace: molecular_function def: "Catalysis of the reaction: glycerol + acceptor = glycerone + reduced acceptor." [EC:1.1.99.22, MetaCyc:GLYCEROL-DEHYDROGENASE-(ACCEPTOR)-RXN] synonym: "glycerol:(acceptor) 1-oxidoreductase activity" EXACT [EC:1.1.99.22] synonym: "glycerol:acceptor 1-oxidoreductase activity" EXACT [EC:1.1.99.22] xref: EC:1.1.99.22 xref: GO:0047955 xref: MetaCyc:GLYCEROL-DEHYDROGENASE-(ACCEPTOR)-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007255 name: glycerol dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH." [EC:1.1.1.72, MetaCyc:GLYCEROL-DEHYDROGENASE-(NADP+)-RXN] synonym: "glycerol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.72] xref: EC:1.1.1.72 xref: GO:0047956 xref: MetaCyc:GLYCEROL-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007256 name: 4'-methoxyisoflavone 2'-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O." [EC:1.14.13.53, MetaCyc:ISOFLAVONE-2] synonym: "formononetin,NADPH:oxygen oxidoreductase (2'-hydroxylating)" EXACT [EC:1.14.13.53] synonym: "isoflavone 2'-monooxygenase activity" BROAD [EC:1.14.13.53] xref: EC:1.14.13.53 xref: GO:0047957 xref: MetaCyc:ISOFLAVONE-2 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007257 name: glycine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate." [EC:2.6.1.4, MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN] synonym: "glutamate-glyoxylate transaminase activity" EXACT [] synonym: "glutamic-glyoxylic transaminase activity" EXACT [EC:2.6.1.4] synonym: "glycine aminotransferase activity" EXACT [] synonym: "glycine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.4] synonym: "glyoxylate-glutamate aminotransferase activity" EXACT [EC:2.6.1.4] synonym: "glyoxylate-glutamic transaminase activity" EXACT [EC:2.6.1.4] synonym: "L-glutamate:glyoxylate aminotransferase activity" EXACT [] xref: EC:2.6.1.4 xref: GO:0047958 xref: MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007258 name: glycine dehydrogenase (cytochrome) activity namespace: molecular_function def: "Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c." [EC:1.4.2.1, MetaCyc:GLYCINE-DEHYDROGENASE-(CYTOCHROME)-RXN] synonym: "glycine-cytochrome c reductase activity" EXACT [EC:1.4.2.1] synonym: "glycine:ferricytochrome-c oxidoreductase (deaminating)" EXACT [EC:1.4.2.1] synonym: "reductase, glycine-cytochrome c" EXACT [EC:1.4.2.1] xref: EC:1.4.2.1 xref: GO:0047959 xref: MetaCyc:GLYCINE-DEHYDROGENASE-(CYTOCHROME)-RXN is_a: CCO:F0003240 ! oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor [Term] id: CCO:F0007259 name: glycine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH." [EC:1.4.1.10, MetaCyc:GLYCINE-DEHYDROGENASE-RXN] synonym: "glycine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.10] xref: EC:1.4.1.10 xref: GO:0047960 xref: MetaCyc:GLYCINE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007260 name: glycine N-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine." [EC:2.3.1.13, MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN] synonym: "acyl-CoA:glycine N-acyltransferase activity" EXACT [EC:2.3.1.13] synonym: "glycine acyltransferase activity" EXACT [EC:2.3.1.13] synonym: "glycine-N-acylase activity" EXACT [EC:2.3.1.13] xref: EC:2.3.1.13 xref: GO:0047961 xref: MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0007261 name: glycine N-benzoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: benzoyl-CoA + glycine = CoA + N-benzoylglycine." [EC:2.3.1.71, MetaCyc:GLYCINE-N-BENZOYLTRANSFERASE-RXN] synonym: "benzoyl CoA-amino acid N-acyltransferase activity" EXACT [EC:2.3.1.71] synonym: "benzoyl-CoA:glycine N-acyltransferase activity" EXACT [EC:2.3.1.71] synonym: "benzoyl-CoA:glycine N-benzoyltransferase activity" EXACT [EC:2.3.1.71] xref: EC:2.3.1.71 xref: GO:0047962 xref: MetaCyc:GLYCINE-N-BENZOYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007262 name: glycine N-choloyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate." [EC:2.3.1.65, MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN] synonym: "amino acid N-choloyltransferase activity" EXACT [EC:2.3.1.65] synonym: "BACAT activity" EXACT [EC:2.3.1.65] synonym: "BAT activity" EXACT [EC:2.3.1.65] synonym: "bile acid-CoA:amino acid N-acyltransferase activity" EXACT [EC:2.3.1.65] synonym: "choloyl-CoA:glycine N-choloyltransferase activity" EXACT [EC:2.3.1.65] synonym: "cholyl-CoA glycine-taurine N-acyltransferase activity" EXACT [EC:2.3.1.65] synonym: "cholyl-CoA:taurine N-acyltransferase activity" EXACT [EC:2.3.1.65] synonym: "glycine--taurine N-acyltransferase activity" EXACT [EC:2.3.1.65] xref: EC:2.3.1.65 xref: GO:0047963 xref: MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007263 name: glyoxylate reductase activity namespace: molecular_function def: "Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH." [EC:1.1.1.26, MetaCyc:GLYCOLATE-REDUCTASE-RXN] subset: gosubset_prok synonym: "glycolate reductase activity" EXACT [] synonym: "glyoxylic acid reductase activity" EXACT [EC:1.1.1.26] synonym: "NADH-dependent glyoxylate reductase activity" EXACT [EC:1.1.1.26] xref: EC:1.1.1.26 xref: GO:0047964 xref: MetaCyc:GLYCOLATE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007264 name: glycoprotein O-fatty-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein." [EC:2.3.1.142, MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN] synonym: "fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity" EXACT [EC:2.3.1.142] synonym: "protein acyltransferase activity" EXACT [EC:2.3.1.142] xref: EC:2.3.1.142 xref: GO:0047965 xref: MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN is_a: CCO:F0003139 ! O-palmitoyltransferase activity [Term] id: CCO:F0007265 name: glycosulfatase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose 6-sulfate + H2O = D-glucose + SO4(2-) (sulfate)." [EC:3.1.6.3, MetaCyc:GLYCOSULFATASE-RXN] synonym: "glucosulfatase activity" EXACT [EC:3.1.6.3] synonym: "glycosulphatase activity" EXACT [] synonym: "sugar-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.3] xref: EC:3.1.6.3 xref: GO:0047966 xref: MetaCyc:GLYCOSULFATASE-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0007266 name: glycyrrhizinate beta-glucuronidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + glycyrrhizinate = 1,2-beta-D-glucuronosyl-D-glucuronate + glycyrrhetinate." [EC:3.2.1.128, MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN] synonym: "glycyrrhizin beta-hydrolase activity" EXACT [EC:3.2.1.128] synonym: "glycyrrhizin hydrolase activity" EXACT [EC:3.2.1.128] synonym: "glycyrrhizinate b-glucuronidase activity" EXACT [] synonym: "glycyrrhizinate glucuronosylhydrolase activity" EXACT [EC:3.2.1.128] synonym: "glycyrrhizinic acid hydrolase activity" EXACT [EC:3.2.1.128] xref: EC:3.2.1.128 xref: GO:0047967 xref: MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007267 name: glyoxylate dehydrogenase (acylating) activity namespace: molecular_function def: "Catalysis of the reaction: glyoxylate + CoA + NADP+ = oxalyl-CoA + NADPH." [EC:1.2.1.17, MetaCyc:GLYOXYLATE-DEHYDROGENASE-(ACYLATING)-RXN] synonym: "glyoxylate:NADP+ oxidoreductase (CoA-oxalylating)" EXACT [EC:1.2.1.17] xref: EC:1.2.1.17 xref: GO:0047968 xref: MetaCyc:GLYOXYLATE-DEHYDROGENASE-(ACYLATING)-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007268 name: glyoxylate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: glyoxylate + H2O + O2 = oxalate + H2O2." [EC:1.2.3.5, MetaCyc:GLYOXYLATE-OXIDASE-RXN] synonym: "glyoxylate:oxygen oxidoreductase activity" EXACT [EC:1.2.3.5] xref: EC:1.2.3.5 xref: GO:0047969 xref: MetaCyc:GLYOXYLATE-OXIDASE-RXN is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0007269 name: guanidinoacetase activity namespace: molecular_function def: "Catalysis of the reaction: guanidinoacetate + H2O = glycine + urea." [EC:3.5.3.2, MetaCyc:GUANIDINOACETASE-RXN] synonym: "glycocyaminase activity" EXACT [EC:3.5.3.2] synonym: "guanidinoacetate amidinohydrolase activity" EXACT [EC:3.5.3.2] xref: EC:3.5.3.2 xref: GO:0047970 xref: MetaCyc:GUANIDINOACETASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007270 name: guanidinobutyrase activity namespace: molecular_function def: "Catalysis of the reaction: 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea." [EC:3.5.3.7, MetaCyc:GUANIDINOBUTYRASE-RXN] subset: gosubset_prok synonym: "4-guanidinobutanoate amidinohydrolase activity" EXACT [EC:3.5.3.7] synonym: "4-guanidinobutyrate amidinobutyrase activity" EXACT [EC:3.5.3.7] synonym: "G-base activity" EXACT [EC:3.5.3.7] synonym: "gamma-guanidinobutyrate amidinohydrolase activity" EXACT [EC:3.5.3.7] synonym: "gamma-guanidobutyrase activity" EXACT [EC:3.5.3.7] synonym: "GBH" RELATED [EC:3.5.3.7] synonym: "guanidinobutyrate ureahydrolase activity" EXACT [EC:3.5.3.7] xref: EC:3.5.3.7 xref: GO:0047971 xref: MetaCyc:GUANIDINOBUTYRASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007271 name: guanidinopropionase activity namespace: molecular_function def: "Catalysis of the reaction: 3-guanidinopropanoate + H2O = beta-alanine + urea." [EC:3.5.3.17, MetaCyc:GUANIDINOPROPIONASE-RXN] synonym: "3-guanidinopropanoate amidinopropionase activity" EXACT [EC:3.5.3.17] synonym: "GPase activity" EXACT [EC:3.5.3.17] synonym: "GPH" RELATED [EC:3.5.3.17] xref: EC:3.5.3.17 xref: GO:0047972 xref: MetaCyc:GUANIDINOPROPIONASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007272 name: guanidinoacetate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + guanidinoacetate = ADP + phosphoguanidinoacetate." [EC:2.7.3.1, MetaCyc:GUANIDOACETATE-KINASE-RXN] synonym: "ATP:guanidinoacetate N-phosphotransferase activity" EXACT [EC:2.7.3.1] synonym: "glycocyamine kinase activity" EXACT [EC:2.7.3.1] synonym: "guanidoacetate kinase activity" EXACT [] xref: EC:2.7.3.1 xref: GO:0047973 xref: MetaCyc:GUANIDOACETATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0007273 name: guanosine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: guanosine + H2O = xanthosine + NH3." [EC:3.5.4.15, MetaCyc:GUANOSINE-DEAMINASE-RXN] synonym: "guanosine aminase activity" EXACT [EC:3.5.4.15] synonym: "guanosine aminohydrolase activity" EXACT [EC:3.5.4.15] xref: EC:3.5.4.15 xref: GO:0047974 xref: MetaCyc:GUANOSINE-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007274 name: guanosine phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate." [EC:2.4.2.15, MetaCyc:GUANPHOSPHOR-RXN] synonym: "guanosine:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.15] synonym: "guanosine:phosphate D-ribosyltransferase activity" EXACT [EC:2.4.2.15] xref: EC:2.4.2.15 xref: GO:0047975 xref: MetaCyc:GUANPHOSPHOR-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0007275 name: hamamelose kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-hamamelose = ADP + D-hamamelose 2'-phosphate." [EC:2.7.1.102, MetaCyc:HAMAMELOSE-KINASE-RXN] synonym: "ATP/hamamelose 2'-phosphotransferase activity" EXACT [EC:2.7.1.102] synonym: "ATP:D-hamamelose 2'-phosphotransferase activity" EXACT [EC:2.7.1.102] synonym: "hamamelose kinase (phosphorylating)" EXACT [EC:2.7.1.102] synonym: "hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)" EXACT [EC:2.7.1.102] xref: EC:2.7.1.102 xref: GO:0047976 xref: MetaCyc:HAMAMELOSE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007276 name: hepoxilin-epoxide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate." [EC:3.3.2.7, MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN] synonym: "(5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase activity" EXACT [EC:3.3.2.7] synonym: "hepoxilin A(3) hydrolase activity" RELATED [EC:3.3.2.7] synonym: "hepoxilin A3 hydrolase activity" EXACT [EC:3.3.2.7] synonym: "hepoxilin epoxide hydrolase activity" EXACT [EC:3.3.2.7] synonym: "hepoxylin hydrolase activity" RELATED [EC:3.3.2.7] xref: EC:3.3.2.7 xref: GO:0047977 xref: MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0007277 name: hexadecanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH." [EC:1.1.1.164, MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN] synonym: "hexadecanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.164] xref: EC:1.1.1.164 xref: GO:0047978 xref: MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007278 name: hexose oxidase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2." [EC:1.1.3.5, MetaCyc:HEXOSE-OXIDASE-RXN] synonym: "D-hexose:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.5] xref: EC:1.1.3.5 xref: GO:0047979 xref: MetaCyc:HEXOSE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007279 name: hippurate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: hippurate + H2O = benzoate + glycine." [EC:3.5.1.32, MetaCyc:HIPPURATE-HYDROLASE-RXN] subset: gosubset_prok synonym: "benzoylglycine amidohydrolase activity" EXACT [EC:3.5.1.32] synonym: "hippuricase activity" EXACT [EC:3.5.1.32] synonym: "N-benzoylamino-acid amidohydrolase activity" EXACT [EC:3.5.1.32] xref: EC:3.5.1.32 xref: GO:0047980 xref: MetaCyc:HIPPURATE-HYDROLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007280 name: histidine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-histidine = CoA + N-acetyl-L-histidine." [EC:2.3.1.33, MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:L-histidine N-acetyltransferase activity" EXACT [EC:2.3.1.33] synonym: "acetylhistidine synthetase activity" EXACT [EC:2.3.1.33] synonym: "histidine acetyltransferase activity" EXACT [EC:2.3.1.33] xref: EC:2.3.1.33 xref: GO:0047981 xref: MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0007281 name: homocysteine desulfhydrase activity namespace: molecular_function def: "Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate." [EC:4.4.1.2, MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN] synonym: "homocysteine desulfurase activity" EXACT [EC:4.4.1.2] synonym: "L-homocysteine hydrogen-sulfide-lyase (deaminating)" EXACT [EC:4.4.1.2] synonym: "L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)" EXACT [EC:4.4.1.2] xref: EC:4.4.1.2 xref: GO:0047982 xref: MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007282 name: homoglutathione synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + gamma-L-glutamyl-L-cysteine + beta-alanine = ADP + phosphate + gamma-L-glutamyl-L-cysteinyl-beta-alanine." [EC:6.3.2.23, MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN] synonym: "beta-alanine specific hGSH synthetase activity" EXACT [EC:6.3.2.23] synonym: "gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming)" EXACT [EC:6.3.2.23] synonym: "homoglutathione synthetase activity" EXACT [EC:6.3.2.23] xref: EC:6.3.2.23 xref: GO:0047983 xref: MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0007283 name: hydrogen dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2 + NAD+ = H+ + NADH." [EC:1.12.1.2, MetaCyc:HYDROGEN-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "bidirectional hydrogenase activity" BROAD [EC:1.12.1.2] synonym: "H(2):NAD(+) oxidoreductase activity" EXACT [EC:1.12.1.2] synonym: "H2:NAD+ oxidoreductase activity" EXACT [EC:1.12.1.2] synonym: "hydrogen:NAD+ oxidoreductase activity" EXACT [EC:1.12.1.2] synonym: "hydrogenase activity" BROAD [EC:1.12.1.2] synonym: "NAD-linked hydrogenase activity" EXACT [EC:1.12.1.2] xref: EC:1.12.1.2 xref: GO:0047985 xref: MetaCyc:HYDROGEN-DEHYDROGENASE-RXN is_a: CCO:F0003282 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor [Term] id: CCO:F0007284 name: hydrogen-sulfide S-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + hydrogen sulfide = CoA + thioacetate." [EC:2.3.1.10, MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:hydrogen-sulfide S-acetyltransferase activity" EXACT [EC:2.3.1.10] synonym: "hydrogen-sulfide acetyltransferase activity" EXACT [EC:2.3.1.10] synonym: "hydrogen-sulphide S-acetyltransferase activity" EXACT [] xref: EC:2.3.1.10 xref: GO:0047986 xref: MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN is_a: CCO:F0003141 ! S-acetyltransferase activity [Term] id: CCO:F0007285 name: hydroperoxide dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate = (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate + H2O." [EC:4.2.1.92, MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN] synonym: "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]" RELATED [EC:4.2.1.92] synonym: "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase activity" EXACT [EC:4.2.1.92] synonym: "HPI" RELATED [EC:4.2.1.92] synonym: "hydroperoxide isomerase activity" EXACT [EC:4.2.1.92] synonym: "linoleate hydroperoxide isomerase" RELATED [EC:4.2.1.92] synonym: "linoleic acid hydroperoxide isomerase" RELATED [EC:4.2.1.92] xref: EC:4.2.1.92 xref: GO:0047987 xref: MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007286 name: hydroxyacid-oxoacid transhydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate." [EC:1.1.99.24, MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN] synonym: "(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity" EXACT [EC:1.1.99.24] synonym: "transhydrogenase, hydroxy acid-oxo acid" EXACT [EC:1.1.99.24] xref: EC:1.1.99.24 xref: GO:0047988 xref: MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007287 name: hydroxybutyrate-dimer hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O = 2 (R)-3-hydroxybutanoate." [EC:3.1.1.22, MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN] subset: gosubset_prok synonym: "(R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase activity" EXACT [EC:3.1.1.22] synonym: "D-(-)-3-hydroxybutyrate-dimer hydrolase activity" EXACT [EC:3.1.1.22] xref: EC:3.1.1.22 xref: GO:0047989 xref: MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007288 name: hydroxyglutamate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-L-glutamate = 4-amino-3-hydroxybutanoate + CO2." [EC:4.1.1.16, MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN] synonym: "3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming)" EXACT [EC:4.1.1.16] synonym: "3-hydroxy-L-glutamate 1-carboxy-lyase activity" EXACT [EC:4.1.1.16] xref: EC:4.1.1.16 xref: GO:0047990 xref: MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007289 name: hydroxylamine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxylamine + O2 = NO2(-) (nitrite) + H2O." [EC:1.7.3.4, MetaCyc:HYDROXYLAMINE-OXIDASE-RXN] subset: gosubset_prok synonym: "HAO" RELATED [EC:1.7.3.4] synonym: "hydroxylamine oxidoreductase" BROAD [EC:1.7.3.4] synonym: "hydroxylamine:oxygen oxidoreductase activity" EXACT [EC:1.7.3.4] xref: EC:1.7.3.4 xref: GO:0047991 xref: MetaCyc:HYDROXYLAMINE-OXIDASE-RXN is_a: CCO:F0003258 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor [Term] id: CCO:F0007290 name: hydroxylysine kinase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 5-hydroxy-L-lysine = GDP + 5-phosphonooxy-L-lysine." [EC:2.7.1.81, MetaCyc:HYDROXYLYSINE-KINASE-RXN] synonym: "GTP:5-hydroxy-L-lysine O-phosphotransferase activity" EXACT [EC:2.7.1.81] synonym: "guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity" EXACT [EC:2.7.1.81] synonym: "hydroxylysine kinase (phosphorylating)" EXACT [EC:2.7.1.81] xref: EC:2.7.1.81 xref: GO:0047992 xref: MetaCyc:HYDROXYLYSINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007291 name: hydroxymalonate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxymalonate + NAD+ = oxomalonate + NADH." [EC:1.1.1.167, MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN] synonym: "hydroxymalonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.167] xref: EC:1.1.1.167 xref: GO:0047993 xref: MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007292 name: hydroxymethylglutaryl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H2O = CoA + 3-hydroxy-3-methylglutarate." [EC:3.1.2.5, MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN] synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase activity" EXACT [EC:3.1.2.5] synonym: "3-hydroxy-3-methylglutaryl-CoA hydrolase activity" EXACT [EC:3.1.2.5] synonym: "beta-hydroxy-beta-methylglutaryl coenzyme A deacylase activity" EXACT [EC:3.1.2.5] synonym: "beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase activity" EXACT [EC:3.1.2.5] synonym: "hydroxymethylglutaryl coenzyme A deacylase activity" EXACT [EC:3.1.2.5] synonym: "hydroxymethylglutaryl coenzyme A hydrolase activity" EXACT [EC:3.1.2.5] xref: EC:3.1.2.5 xref: GO:0047994 xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0007293 name: hydroxyphenylpyruvate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH." [EC:1.1.1.237, MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN] synonym: "4-hydroxyphenyllactate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.237] synonym: "HPRP" RELATED [EC:1.1.1.237] xref: EC:1.1.1.237 xref: GO:0047995 xref: MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007294 name: hydroxyphytanate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-hydroxyphytanate + O2 = 2-oxophytanate + H2O2." [EC:1.1.3.27, MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN] synonym: "L-2-hydroxyphytanate:oxygen 2-oxidoreductase" BROAD [EC:1.1.3.27] xref: EC:1.1.3.27 xref: GO:0047996 xref: MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007295 name: hydroxypyruvate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxypyruvate = glycolaldehyde + CO2." [EC:4.1.1.40, MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN] synonym: "hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)" EXACT [EC:4.1.1.40] synonym: "hydroxypyruvate carboxy-lyase activity" EXACT [EC:4.1.1.40] xref: EC:4.1.1.40 xref: GO:0047997 xref: MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007296 name: hyoscyamine (6S)-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-hyoscyamine + 2-oxoglutarate + O2 = (6S)-hydroxyhyoscyamine + succinate + CO2." [EC:1.14.11.11, MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN] synonym: "hyoscyamine (6S)-hydroxylase activity" EXACT [EC:1.14.11.11] synonym: "hyoscyamine 6-beta-hydroxylase activity" EXACT [EC:1.14.11.11] synonym: "hyoscyamine 6-hydroxylase activity" EXACT [EC:1.14.11.11] synonym: "hyoscyamine 6beta-dioxygenase activity" EXACT [EC:1.14.11.11] synonym: "hyoscyamine 6beta-hydroxylase activity" EXACT [EC:1.14.11.11] synonym: "L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)" EXACT [EC:1.14.11.11] xref: EC:1.14.11.11 xref: GO:0047998 xref: MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0007297 name: hyponitrite reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 hydroxylamine + 2 NAD+ = hyponitrous acid + 2 NADH + 2 H+." [EC:1.7.1.5, MetaCyc:HYPONITRITE-REDUCTASE-RXN] synonym: "hydroxylamine:NAD+ oxidoreductase activity" EXACT [EC:1.7.1.5] synonym: "NADH2:hyponitrite oxidoreductase activity" EXACT [EC:1.7.1.5] synonym: "NADH:hyponitrite oxidoreductase activity" EXACT [EC:1.7.1.5] xref: EC:1.7.1.5 xref: GO:0047999 xref: MetaCyc:HYPONITRITE-REDUCTASE-RXN is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0007298 name: isoflavone 3'-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O." [EC:1.14.13.52, MetaCyc:ISOFLAVONE-3] synonym: "formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.13.52] synonym: "isoflavone 3'-monooxygenase activity" EXACT [EC:1.14.13.52] xref: EC:1.14.13.52 xref: GO:0048000 xref: MetaCyc:RXN-3762 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007299 name: erythrose-4-phosphate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-erythrose 4-phosphate + NAD+ + H2O = 4-phosphoerythronate + NADH + 2 H+." [EC:1.2.1.72, MetaCyc:ERYTH4PDEHYDROG-RXN] synonym: "D-erythrose 4-phosphate:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.72] synonym: "E4P dehydrogenase activity" EXACT [EC:1.2.1.72] synonym: "E4PDH" EXACT [EC:1.2.1.72] synonym: "Epd dehydrogenase activity" EXACT [EC:1.2.1.72] synonym: "erythrose 4-phosphate dehydrogenase activity" EXACT [EC:1.2.1.72] synonym: "GapB" RELATED [EC:1.2.1.72] xref: EC:1.2.1.72 xref: GO:0033724 xref: GO:0048001 xref: MetaCyc:ERYTH4PDEHYDROG-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007300 name: receptor agonist activity namespace: molecular_function def: "Interacts with receptors such that the proportion of receptors in the active form is increased." [GOC:ceb, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0048018 is_a: CCO:F0001407 ! receptor binding is_a: CCO:F0004458 ! receptor activator activity [Term] id: CCO:F0007301 name: receptor antagonist activity namespace: molecular_function def: "Interacts with receptors to reduce the action of another ligand, the agonist." [GOC:ceb, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0048019 is_a: CCO:F0001407 ! receptor binding is_a: CCO:F0004459 ! receptor inhibitor activity [Term] id: CCO:F0007302 name: CCR chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a CCR chemokine receptor." [GOC:ai] synonym: "beta chemokine receptor binding" EXACT [] synonym: "beta chemokine receptor ligand" NARROW [] synonym: "CCR chemokine receptor ligand" NARROW [] xref: GO:0048020 is_a: CCO:F0005665 ! chemokine receptor binding [Term] id: CCO:F0007303 name: mRNA 5'-UTR binding namespace: molecular_function def: "Interacting selectively with the 5' untranslated region of an mRNA molecule." [GOC:jic] subset: gosubset_prok synonym: "mRNA 5' UTR binding" EXACT [] xref: GO:0048027 is_a: CCO:F0000313 ! mRNA binding [Term] id: CCO:F0007304 name: galacturonan binding namespace: molecular_function def: "Interacting selectively with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins." [GOC:jic] subset: gosubset_prok synonym: "polygalacturonide binding" RELATED [] xref: GO:0048028 is_a: CCO:F0004357 ! polysaccharide binding [Term] id: CCO:F0007305 name: monosaccharide binding namespace: molecular_function def: "Interacting selectively with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GOC:jic] subset: gosubset_prok xref: GO:0048029 is_a: CCO:F0001659 ! sugar binding [Term] id: CCO:F0007306 name: disaccharide binding namespace: molecular_function def: "Interacting selectively with any disaccharide. Disaccharides are sugars composed of two monosaccharide units." [GOC:jic] xref: GO:0048030 is_a: CCO:F0001659 ! sugar binding [Term] id: CCO:F0007307 name: trisaccharide binding namespace: molecular_function def: "Interacting selectively with any trisaccharide. Trisaccharides are sugars composed of three monosaccharide units." [GOC:jic] xref: GO:0048031 is_a: CCO:F0001659 ! sugar binding [Term] id: CCO:F0007308 name: galacturonate binding namespace: molecular_function def: "Interacting selectively with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group." [GOC:jic] synonym: "galacturonic acid binding" EXACT [] xref: GO:0048032 is_a: CCO:F0007305 ! monosaccharide binding [Term] id: CCO:F0007309 name: cofactor binding namespace: molecular_function def: "Interacting selectively with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_pir subset: gosubset_prok xref: GO:0048037 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0007310 name: quinone binding namespace: molecular_function def: "Interacting selectively with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0048038 is_a: CCO:F0007309 ! cofactor binding [Term] id: CCO:F0007311 name: ubiquinone binding namespace: molecular_function def: "Interacting selectively with ubiquinone, a quinone derivative with a tail of isoprene units." [GOC:jic, ISBN:0582227089] subset: gosubset_prok synonym: "coenzyme Q binding" EXACT [] synonym: "coenzyme Q6 binding" NARROW [] xref: GO:0048039 is_a: CCO:F0007310 ! quinone binding [Term] id: CCO:F0007312 name: UDP-glucuronate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-D-glucuronic acid = UDP-D-xylose + CO2." [EC:4.1.1.35, PMID:11593010] synonym: "UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)" EXACT [EC:4.1.1.35] synonym: "UDP-D-glucuronate carboxy-lyase activity" EXACT [EC:4.1.1.35] synonym: "UDP-glucuronic acid decarboxylase activity" EXACT [] synonym: "UDPglucuronate decarboxylase activity" EXACT [EC:4.1.1.35] synonym: "uridine-diphosphoglucuronate decarboxylase activity" EXACT [EC:4.1.1.35] xref: EC:4.1.1.35 xref: GO:0048040 xref: MetaCyc:UDP-GLUCURONATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007313 name: trans-pentaprenyltranstransferase activity namespace: molecular_function def: "Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = diphosphate + all-trans-hexaprenyl diphosphate." [EC:2.5.1.33] subset: gosubset_prok synonym: "all-trans-hexaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.33] synonym: "all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase activity" EXACT [EC:2.5.1.33] synonym: "hexaprenyl diphosphate synthase activity" EXACT [EC:2.5.1.33] synonym: "hexaprenyl pyrophosphate synthetase activity" EXACT [] xref: EC:2.5.1.33 xref: GO:0048045 xref: MetaCyc:TRANS-PENTAPRENYLTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007314 name: calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive." [GOC:jic] synonym: "calcium- and calmodulin-regulated cGMP phosphodiesterase activity" RELATED [] synonym: "calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity" EXACT [] synonym: "calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity" EXACT [] synonym: "calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity" EXACT [] xref: GO:0048101 is_a: CCO:F0006858 ! 3',5'-cyclic-GMP phosphodiesterase activity [Term] id: CCO:F0007315 name: S100 beta binding namespace: molecular_function def: "Interacting selectively with S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS." [GOC:jic] xref: GO:0048154 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0007316 name: S100 alpha binding namespace: molecular_function def: "Interacting selectively with S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS." [GOC:jic] xref: GO:0048155 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0007317 name: tau protein binding namespace: molecular_function def: "Interacting selectively with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS." [GOC:jic] xref: GO:0048156 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0007318 name: follistatin binding namespace: molecular_function def: "Interacting selectively with follistatin." [GOC:jic] xref: GO:0048184 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0007319 name: activin binding namespace: molecular_function def: "Interacting selectively with activin." [GOC:jic] xref: GO:0048185 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0007320 name: inhibin beta-A binding namespace: molecular_function def: "Interacting selectively with inhibin beta-A." [GOC:jic] xref: GO:0048186 is_a: CCO:F0007318 ! follistatin binding is_a: CCO:F0007319 ! activin binding [Term] id: CCO:F0007321 name: inhibin beta-B binding namespace: molecular_function def: "Interacting selectively with inhibin beta-B." [GOC:jic] xref: GO:0048187 is_a: CCO:F0007318 ! follistatin binding is_a: CCO:F0007319 ! activin binding [Term] id: CCO:F0007322 name: phytanoyl-CoA dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: phytanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyphytanoyl-CoA + succinate + CO2." [EC:1.14.11.18, GOC:jic] synonym: "phytanoyl-CoA 2 oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.18] synonym: "phytanoyl-CoA 2-hydroxylase activity" EXACT [EC:1.14.11.18] synonym: "phytanoyl-CoA alpha-hydroxylase activity" EXACT [EC:1.14.11.18] synonym: "phytanoyl-CoA hydroxylase activity" EXACT [EC:1.14.11.18] synonym: "phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.11.18] xref: EC:1.14.11.18 xref: GO:0048244 xref: MetaCyc:1.14.11.18-RXN is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0007323 name: CXCR3 chemokine receptor binding namespace: molecular_function def: "Interacting selectively with a the CXCR3 chemokine receptor." [GOC:jic, PMID:10556837] xref: GO:0048248 is_a: CCO:F0006097 ! CXCR chemokine receptor binding [Term] id: CCO:F0007324 name: high affinity phosphate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of phosphate from one side of the membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations." [GOC:jic, PMID:8709965] xref: GO:0048249 is_a: CCO:F0002592 ! phosphate transmembrane transporter activity [Term] id: CCO:F0007325 name: flap endonuclease activity namespace: molecular_function def: "Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis." [GOC:jic] subset: gosubset_prok xref: EC:3.1.-.-. xref: GO:0048256 is_a: CCO:F0000917 ! endodeoxyribonuclease activity [Term] id: CCO:F0007326 name: 3'-flap endonuclease activity namespace: molecular_function def: "Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis." [GOC:jic, PMID:10635319] synonym: "3' flap endonuclease activity" EXACT [] xref: GO:0048257 is_a: CCO:F0003447 ! endodeoxyribonuclease activity, producing 3'-phosphomonoesters is_a: CCO:F0007325 ! flap endonuclease activity [Term] id: CCO:F0007327 name: 3-ketoglucose-reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose." [MetaCyc:KETOGLUCOSE-REDUCTASE-RXN] xref: EC:1.1.1.- xref: GO:0048258 xref: MetaCyc:KETOGLUCOSE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007328 name: methionine adenosyltransferase regulator activity namespace: molecular_function def: "Modulates the activity of methionine adenosyltransferase." [EC:2.5.1.6, GOC:jic, PMID:10644686] comment: See also the molecular function term 'methionine adenosyltransferase activity ; GO:0004478'. synonym: "MAT regulator activity" EXACT [] xref: GO:0048270 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0007329 name: mitogen-activated protein kinase p38 binding namespace: molecular_function def: "Interacting selectively with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation." [http://cancerweb.ncl.ac.uk] synonym: "MAPK p38 binding" EXACT [] xref: GO:0048273 is_a: CCO:F0008037 ! mitogen-activated protein kinase binding [Term] id: CCO:F0007330 name: calcium-dependent protein binding namespace: molecular_function def: "Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium." [GOC:jic, PMID:10485905] xref: GO:0048306 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0007331 name: ferredoxin-nitrite reductase activity namespace: molecular_function def: "Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = NO2(-) (nitrite) + 6 reduced ferredoxin + 7 H+." [EC:1.7.7.1, GOC:jic] subset: gosubset_prok synonym: "ammonia:ferredoxin oxidoreductase activity" EXACT [EC:1.7.7.1] xref: EC:1.7.7.1 xref: GO:0048307 is_a: CCO:F0003259 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor [Term] id: CCO:F0007332 name: Rac GTPase binding namespace: molecular_function def: "Interacting selectively with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases." [GOC:ebc, PMID:11702775] xref: GO:0048365 is_a: CCO:F0003531 ! Rho GTPase binding [Term] id: CCO:F0007333 name: brain-derived neurotrophic factor binding namespace: molecular_function def: "Interacting selectively with brain-derived neurotrophic factor." [GOC:dgh] synonym: "BDNF binding" EXACT [] synonym: "neurotrophin TRKB receptor activity" RELATED [] xref: GO:0048403 is_a: CCO:F0005795 ! neurotrophin binding [Term] id: CCO:F0007334 name: neurotrophin-3 binding namespace: molecular_function def: "Interacting selectively with neurotrophin-3." [GOC:dgh] synonym: "neurotrophin 3 binding" EXACT [] synonym: "neurotrophin TRKA receptor activity" RELATED [] synonym: "neurotrophin TRKB receptor activity" RELATED [] synonym: "neurotrophin TRKC receptor activity" RELATED [] synonym: "NT-3 binding" EXACT [] synonym: "NT3 binding" EXACT [] xref: GO:0048404 is_a: CCO:F0005795 ! neurotrophin binding [Term] id: CCO:F0007335 name: neurotrophin-4/5 binding namespace: molecular_function def: "Interacting selectively with neurotrophin-4/5." [GOC:dgh] comment: Note that mammalian NT-5 was initially named differently from amphibian NT-4 because of sequence differences, but the two genes were later shown to be functionally equivalent [SF:919858]. synonym: "neurotrophin 4/5 binding" EXACT [] synonym: "neurotrophin TRKB receptor activity" RELATED [] synonym: "NT 4/5 binding" EXACT [] synonym: "NT-4 binding" NARROW [] synonym: "NT-4/5 binding" EXACT [] synonym: "NT-5 binding" NARROW [] synonym: "NT4 binding" NARROW [] synonym: "NT5 binding" NARROW [] xref: GO:0048405 is_a: CCO:F0005795 ! neurotrophin binding [Term] id: CCO:F0007336 name: nerve growth factor binding namespace: molecular_function def: "Interacting selectively with nerve growth factor." [GOC:dgh] synonym: "neurotrophin TRKA receptor activity" RELATED [] synonym: "NGF binding" EXACT [] xref: GO:0048406 is_a: CCO:F0005795 ! neurotrophin binding [Term] id: CCO:F0007337 name: platelet-derived growth factor binding namespace: molecular_function def: "Interacting selectively with platelet-derived growth factor." [GOC:dgh] synonym: "PDGF binding" EXACT [] xref: GO:0048407 is_a: CCO:F0004188 ! growth factor binding [Term] id: CCO:F0007338 name: epidermal growth factor binding namespace: molecular_function def: "Interacting selectively with epidermal growth factor." [GOC:dgh] synonym: "EGF binding" EXACT [] xref: GO:0048408 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0007339 name: threonine-phosphate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-threonine O-3-phosphate = (R)-1-aminopropan-2-yl phosphate + CO2." [EC:4.1.1.81, GOC:mlg] subset: gosubset_prok synonym: "CobD" RELATED [EC:4.1.1.81] synonym: "L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]" RELATED [EC:4.1.1.81] synonym: "L-threonine O-3-phosphate carboxy-lyase activity" EXACT [EC:4.1.1.81] synonym: "L-threonine-O-3-phosphate decarboxylase activity" EXACT [] xref: EC:4.1.1.81 xref: GO:0048472 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007340 name: D-methionine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of D-methionine from one side of a membrane to the other." [GOC:mlg, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "D-methionine transporter activity" BROAD [] xref: GO:0048474 is_a: CCO:F0006027 ! methionine transmembrane transporter activity [Term] id: CCO:F0007341 name: beta-tubulin binding namespace: molecular_function def: "Interacting selectively with the microtubule constituent protein beta-tubulin." [GOC:krc] synonym: "beta tubulin binding" EXACT [] xref: GO:0048487 is_a: CCO:F0002987 ! tubulin binding [Term] id: CCO:F0007342 name: Roundabout binding namespace: molecular_function def: "Interacting selectively with the Roundabout (ROBO) receptor, a transmembrane receptor." [GOC:ecd, PMID:10102268, PMID:10197527] synonym: "Roundabout receptor binding" RELATED [] xref: GO:0048495 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0007343 name: thiamin-transporting ATPase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O + thiamin(out) = ADP + phosphate + thiamin(in)." [GOC:mlg, PMID:9535878] comment: Consider also annotating to the molecular function term 'ATP binding ; GO:0005524'. synonym: "thiamin ABC transporter" NARROW [] synonym: "thiamine-transporting ATPase activity" EXACT [] xref: GO:0048502 is_a: CCO:F0005699 ! ATPase activity, coupled to transmembrane movement of substances [Term] id: CCO:F0007344 name: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity namespace: molecular_function def: "Catalysis of the reaction: magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O." [EC:1.14.13.81] synonym: "magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.13.81] synonym: "Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase activity" EXACT [EC:1.14.13.81] synonym: "Mg-protoporphyrin IX monomethyl ester oxidative cyclase activity" EXACT [EC:1.14.13.81] xref: EC:1.14.13.81 xref: GO:0048529 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007345 name: beta-1,3-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage." [PMID:11551958] xref: GO:0048531 is_a: CCO:F0001853 ! galactosyltransferase activity [Term] id: CCO:F0007346 name: metalloenzyme inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of metalloenzyme. A metalloenzyme is any enzyme that contains metal." [GOC:ebc] xref: GO:0048551 is_a: CCO:F0001213 ! enzyme inhibitor activity is_a: CCO:F0008375 ! metalloenzyme regulator activity [Term] id: CCO:F0007347 name: fibroblast growth factor 1 binding namespace: molecular_function def: "Interacting selectively with fibroblast growth factor 1." [GOC:ebc] synonym: "FGF 1 binding" EXACT [] xref: GO:0048602 is_a: CCO:F0003590 ! fibroblast growth factor binding [Term] id: CCO:F0007348 name: fibroblast growth factor 2 binding namespace: molecular_function def: "Interacting selectively with fibroblast growth factor 2." [GOC:ebc] synonym: "FGF 2 binding" EXACT [] xref: GO:0048603 is_a: CCO:F0003590 ! fibroblast growth factor binding [Term] id: CCO:F0007349 name: fibroblast growth factor 3 binding namespace: molecular_function def: "Interacting selectively with fibroblast growth factor 3." [GOC:ebc] synonym: "FGF 3 binding" EXACT [] xref: GO:0048604 is_a: CCO:F0003590 ! fibroblast growth factor binding [Term] id: CCO:F0007350 name: fibroblast growth factor 4 binding namespace: molecular_function def: "Interacting selectively with fibroblast growth factor 4." [GOC:ebc] synonym: "FGF 4 binding" EXACT [] xref: GO:0048605 is_a: CCO:F0003590 ! fibroblast growth factor binding [Term] id: CCO:F0007351 name: fibroblast growth factor 5 binding namespace: molecular_function def: "Interacting selectively with fibroblast growth factor 5." [GOC:ebc] synonym: "FGF 5 binding" EXACT [] xref: GO:0048606 is_a: CCO:F0003590 ! fibroblast growth factor binding [Term] id: CCO:F0007352 name: fibroblast growth factor 6 binding namespace: molecular_function def: "Interacting selectively with fibroblast growth factor 6." [GOC:ebc] synonym: "FGF 6 binding" EXACT [] xref: GO:0048607 is_a: CCO:F0003590 ! fibroblast growth factor binding [Term] id: CCO:F0007353 name: calcium-induced calcium release activity namespace: molecular_function def: "Release of calcium ions from an intracellular vesicle on induction by increased calcium concentration." [GOC:jic, GOC:nln, PMID:2990997, PMID:8381210, PMID:8653752] xref: GO:0048763 is_a: CCO:F0001494 ! intracellular ligand-gated calcium channel activity [Term] id: CCO:F0007354 name: D-glutaminase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate." [EC:3.5.1.35, MetaCyc:D-GLUTAMINASE-RXN] synonym: "D-glutamine amidohydrolase activity" EXACT [EC:3.5.1.35] xref: EC:3.5.1.35 xref: GO:0050001 xref: MetaCyc:D-GLUTAMINASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007355 name: D-proline reductase (dithiol) activity namespace: molecular_function def: "Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline." [EC:1.21.4.1, MetaCyc:D-PROLINE-REDUCTASE-(DITHIOL)-RXN] comment: Note that this function was formerly EC:1.4.4.1. synonym: "5-aminopentanoate:lipoate oxidoreductase (cyclizing)" EXACT [EC:1.21.4.1] xref: EC:1.21.4.1 xref: GO:0050002 xref: MetaCyc:1.21.4.1-RXN is_a: CCO:F0007826 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor [Term] id: CCO:F0007356 name: deoxycytidylate C-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = deoxy-5-methylcytidylate + 7,8-dihydrofolate." [EC:2.1.1.54, MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN] synonym: "5,10-methylenetetrahydrofolate:dCMP C-methyltransferase activity" EXACT [EC:2.1.1.54] synonym: "dCMP methyltransferase activity" EXACT [EC:2.1.1.54] synonym: "deoxycytidylate methyltransferase activity" EXACT [EC:2.1.1.54] xref: EC:2.1.1.54 xref: GO:0050003 xref: MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN is_a: CCO:F0001756 ! C-methyltransferase activity [Term] id: CCO:F0007357 name: isoflavone 7-O-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside." [EC:2.4.1.170, MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN] synonym: "UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.170] synonym: "UDPglucose-favonoid 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.170] synonym: "UDPglucose:isoflavone 7-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.170] synonym: "UDPglucose:isoflavone 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.170] synonym: "uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase activity" EXACT [EC:2.4.1.170] xref: EC:2.4.1.170 xref: GO:0050004 xref: MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007358 name: isohexenylglutaconyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)-pent-2-enedioyl-CoA + H2O." [EC:4.2.1.57, MetaCyc:ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN] synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]" RELATED [EC:4.2.1.57] synonym: "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase activity" EXACT [EC:4.2.1.57] synonym: "3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase activity" EXACT [EC:4.2.1.57] synonym: "beta-isohexenylglutaconyl-CoA-hydratase activity" EXACT [EC:4.2.1.57] synonym: "isohexenylglutaconyl coenzyme A hydratase activity" EXACT [EC:4.2.1.57] xref: EC:4.2.1.57 xref: GO:0050005 xref: MetaCyc:ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN xref: UM-BBD_enzymeID:e0722 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007359 name: isomaltulose synthase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose." [EC:5.4.99.11, MetaCyc:ISOMALTULOSE-SYNTHASE-RXN] synonym: "isomaltulose synthetase activity" EXACT [EC:5.4.99.11] synonym: "sucrose alpha-glucosyltransferase activity" EXACT [EC:5.4.99.11] synonym: "sucrose glucosylmutase activity" EXACT [EC:5.4.99.11] synonym: "trehalulose synthase activity" EXACT [EC:5.4.99.11] xref: EC:5.4.99.11 xref: GO:0050006 xref: MetaCyc:ISOMALTULOSE-SYNTHASE-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0007360 name: isonocardicin synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + nocardicin E = 5'-methylthioadenosine + isonocardicin A." [EC:2.5.1.38, MetaCyc:ISONOCARDICIN-SYNTHASE-RXN] synonym: "nocardicin aminocarboxypropyltransferase activity" EXACT [EC:2.5.1.38] synonym: "S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase activity" EXACT [EC:2.5.1.38] xref: EC:2.5.1.38 xref: GO:0050007 xref: MetaCyc:ISONOCARDICIN-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007361 name: isopiperitenone delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: isopiperitenone = piperitenone." [EC:5.3.3.11, MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN] synonym: "isopiperitenone D-isomerase activity" EXACT [] synonym: "isopiperitenone delta8-delta4-isomerase activity" EXACT [EC:5.3.3.11] xref: EC:5.3.3.11 xref: GO:0050008 xref: MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0007362 name: isopropanol dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: propan-2-ol + NADP+ = acetone + NADPH." [EC:1.1.1.80, MetaCyc:ISOPROPANOL-DEHYDROGENASE-(NADP+)-RXN] synonym: "propan-2-ol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.80] xref: EC:1.1.1.80 xref: GO:0050009 xref: MetaCyc:ISOPROPANOL-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007363 name: isovitexin beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + isovitexin = isovitexin 2''-O-beta-D-glucoside + UDP." [EC:2.4.1.106, MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "isovitexin b-glucosyltransferase activity" EXACT [] synonym: "UDP-glucose:isovitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.106] synonym: "UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.106] synonym: "uridine diphosphoglucose-isovitexin 2''-glucosyltransferase activity" EXACT [EC:2.4.1.106] xref: EC:2.4.1.106 xref: GO:0050010 xref: MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007364 name: itaconyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O." [EC:4.2.1.56, MetaCyc:ITACONYL-COA-HYDRATASE-RXN] synonym: "citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)" EXACT [EC:4.2.1.56] synonym: "citramalyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.56] synonym: "itaconyl coenzyme A hydratase activity" EXACT [EC:4.2.1.56] xref: EC:4.2.1.56 xref: GO:0050011 xref: MetaCyc:ITACONYL-COA-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007365 name: juglone 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-hydroxy-1,4-naphthoquinone + donor-H2 + O2 = 3,5-dihydroxy-1,4-naphthoquinone + acceptor + H2O." [EC:1.14.99.27, MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN] synonym: "5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.99.27] synonym: "juglone hydroxylase activity" EXACT [] synonym: "naphthoquinone hydroxylase activity" EXACT [EC:1.14.99.27] synonym: "naphthoquinone-hydroxylase activity" EXACT [EC:1.14.99.27] xref: EC:1.14.99.27 xref: GO:0050012 xref: MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007366 name: 2-dehydropantoate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde." [EC:4.1.2.12, MetaCyc:KETOPANTOALDOLASE-RXN] synonym: "2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)" EXACT [EC:4.1.2.12] synonym: "2-dehydropantoate formaldehyde-lyase activity" EXACT [EC:4.1.2.12] synonym: "ketopantoaldolase activity" EXACT [] xref: EC:4.1.2.12 xref: GO:0050013 xref: MetaCyc:KETOPANTOALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007367 name: ketotetrose-phosphate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: erythrulose 1-phosphate = glycerone phosphate + formaldehyde." [EC:4.1.2.2, MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN] synonym: "erythrose-1-phosphate synthase activity" EXACT [EC:4.1.2.2] synonym: "erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming)" EXACT [EC:4.1.2.2] synonym: "erythrulose-1-phosphate formaldehyde-lyase activity" EXACT [EC:4.1.2.2] synonym: "erythrulose-1-phosphate synthetase activity" EXACT [EC:4.1.2.2] synonym: "phosphoketotetrose aldolase activity" EXACT [EC:4.1.2.2] xref: EC:4.1.2.2 xref: GO:0050014 xref: MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007368 name: kievitone hydratase activity namespace: molecular_function def: "Catalysis of the reaction: kievitone hydrate = kievitone + H2O." [EC:4.2.1.95, MetaCyc:KIEVITONE-HYDRATASE-RXN] synonym: "KHase activity" EXACT [EC:4.2.1.95] synonym: "kievitone-hydrate hydro-lyase (kievitone-forming)" EXACT [EC:4.2.1.95] synonym: "kievitone-hydrate hydro-lyase activity" EXACT [EC:4.2.1.95] xref: EC:4.2.1.95 xref: GO:0050015 xref: MetaCyc:KIEVITONE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007369 name: kynurenine 7,8-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor." [EC:1.14.99.2, MetaCyc:KYNURENINE-7] synonym: "kynurenate 7,8-hydroxylase activity" EXACT [EC:1.14.99.2] synonym: "kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.99.2] synonym: "kynurenic acid hydroxylase activity" EXACT [EC:1.14.99.2] synonym: "kynurenic hydroxylase activity" EXACT [EC:1.14.99.2] xref: EC:1.14.99.2 xref: GO:0050016 xref: MetaCyc:KYNURENINE-7 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007370 name: L-3-cyanoalanine synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine." [EC:4.4.1.9, MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN] synonym: "beta-cyano-L-alanine synthase activity" EXACT [EC:4.4.1.9] synonym: "beta-cyanoalanine synthase activity" EXACT [EC:4.4.1.9] synonym: "beta-cyanoalanine synthetase activity" EXACT [EC:4.4.1.9] synonym: "L-cysteine hydrogen-sulfide-lyase (adding HCN)" EXACT [EC:4.4.1.9] synonym: "L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)" EXACT [EC:4.4.1.9] xref: EC:4.4.1.9 xref: GO:0050017 xref: MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007371 name: L-amino-acid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH." [EC:1.4.1.5, MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN] synonym: "L-amino-acid:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.5] xref: EC:1.4.1.5 xref: GO:0050018 xref: MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007372 name: L-arabinitol 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-arabinitol + NAD+ = L-xylulose + NADH." [EC:1.1.1.12, MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN] xref: EC:1.1.1.12 xref: GO:0050019 xref: MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007373 name: L-arabinonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H2O." [EC:4.2.1.25, MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN] synonym: "L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)" EXACT [EC:4.2.1.25] synonym: "L-arabinonate hydro-lyase activity" EXACT [EC:4.2.1.25] synonym: "L-arabonate dehydrase activity" EXACT [EC:4.2.1.25] synonym: "L-arabonate dehydratase activity" EXACT [EC:4.2.1.25] xref: EC:4.2.1.25 xref: GO:0050020 xref: MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007374 name: L-arabinonolactonase activity namespace: molecular_function def: "Catalysis of the reaction: L-arabinono-1,4-lactone + H2O = L-arabinonate." [EC:3.1.1.15, MetaCyc:L-ARABINONOLACTONASE-RXN] synonym: "L-arabinono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.15] xref: EC:3.1.1.15 xref: GO:0050021 xref: MetaCyc:L-ARABINONOLACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007375 name: L-arabinose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH." [EC:1.1.1.46, MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN] synonym: "L-arabinose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.46] xref: EC:1.1.1.46 xref: GO:0050022 xref: MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007376 name: L-fuconate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O." [EC:4.2.1.68, MetaCyc:L-FUCONATE-HYDRATASE-RXN] synonym: "L-fuconate hydratase activity" EXACT [] synonym: "L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)" EXACT [EC:4.2.1.68] synonym: "L-fuconate hydro-lyase activity" EXACT [EC:4.2.1.68] xref: EC:4.2.1.68 xref: GO:0050023 xref: MetaCyc:L-FUCONATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007377 name: L-galactonolactone oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-galactono-1,4-lactone + O2 = L-ascorbate + H2O2." [EC:1.3.3.12, MetaCyc:L-GALACTONOLACTONE-OXIDASE-RXN] synonym: "L-galactono-1,4-lactone oxidase activity" EXACT [EC:1.3.3.12] synonym: "L-galactono-1,4-lactone:oxygen 3-oxidoreductase activity" EXACT [EC:1.3.3.12] synonym: "L-xylono-1,4-lactone oxidase activity" EXACT [EC:1.3.3.12] xref: EC:1.3.3.12 xref: GO:0033733 xref: GO:0050024 xref: MetaCyc:L-GALACTONOLACTONE-OXIDASE-RXN is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007378 name: L-glutamate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2." [EC:1.4.3.11, MetaCyc:L-GLUTAMATE-OXIDASE-RXN] subset: gosubset_prok synonym: "glutamate (acceptor) dehydrogenase activity" EXACT [EC:1.4.3.11] synonym: "glutamate oxidase activity" EXACT [EC:1.4.3.11] synonym: "glutamic acid oxidase activity" EXACT [EC:1.4.3.11] synonym: "glutamic dehydrogenase (acceptor)" EXACT [EC:1.4.3.11] synonym: "L-glutamate:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.11] synonym: "L-glutamic acid oxidase activity" EXACT [EC:1.4.3.11] xref: EC:1.4.3.11 xref: GO:0050025 xref: MetaCyc:L-GLUTAMATE-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0007379 name: L-glycol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+." [EC:1.1.1.185, MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN] synonym: "glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity" EXACT [EC:1.1.1.185] synonym: "L-(+)-glycol:NAD(P) oxidoreductase activity" EXACT [EC:1.1.1.185] synonym: "L-glycol:NAD(P) dehydrogenase activity" EXACT [EC:1.1.1.185] synonym: "L-glycol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.185] xref: EC:1.1.1.185 xref: GO:0050026 xref: MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007380 name: L-idonate 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH." [EC:1.1.1.128, MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN] synonym: "5-keto-D-gluconate 2-reductase activity" EXACT [EC:1.1.1.128] synonym: "5-ketogluconate 2-reductase activity" EXACT [EC:1.1.1.128] synonym: "5-ketoglucono-idono-reductase activity" EXACT [EC:1.1.1.128] synonym: "5KGR" RELATED [EC:1.1.1.128] synonym: "L-idonate dehydrogenase activity" EXACT [EC:1.1.1.128] synonym: "L-idonate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.128] synonym: "reductase, 5-ketogluconate 5- (L-idonate-forming)" EXACT [EC:1.1.1.128] xref: EC:1.1.1.128 xref: GO:0050027 xref: MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007381 name: L-lysine-lactamase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine 1,6-lactam + H2O = L-lysine." [EC:3.5.2.11, MetaCyc:L-LYSINE-LACTAMASE-RXN] synonym: "L-alpha-aminocaprolactam hydrolase activity" EXACT [EC:3.5.2.11] synonym: "L-lysinamidase activity" EXACT [EC:3.5.2.11] synonym: "L-lysine-1,6-lactam lactamhydrolase activity" EXACT [EC:3.5.2.11] xref: EC:3.5.2.11 xref: GO:0050028 xref: MetaCyc:L-LYSINE-LACTAMASE-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0007382 name: L-lysine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + H2O2." [EC:1.4.3.14, MetaCyc:L-LYSINE-OXIDASE-RXN] synonym: "L-lysine alpha-oxidase activity" EXACT [EC:1.4.3.14] synonym: "L-lysine:oxygen 2-oxidoreductase (deaminating)" EXACT [EC:1.4.3.14] synonym: "L-lysyl-alpha-oxidase activity" EXACT [EC:1.4.3.14] xref: EC:1.4.3.14 xref: GO:0050029 xref: MetaCyc:L-LYSINE-OXIDASE-RXN xref: MetaCyc:PWY-5311 is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0007383 name: L-pipecolate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-pipecolate + acceptor = 2,3,4,5-tetrahydropyridine-2-carboxylate + reduced acceptor." [EC:1.5.99.3, MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN] synonym: "L-pipecolate:(acceptor) 1,6-oxidoreductase activity" EXACT [EC:1.5.99.3] synonym: "L-pipecolate:acceptor 1,6-oxidoreductase activity" EXACT [EC:1.5.99.3] xref: EC:1.5.99.3 xref: GO:0050030 xref: MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0007384 name: L-pipecolate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-pipecolate + O2 = 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2." [EC:1.5.3.7, MetaCyc:L-PIPECOLATE-OXIDASE-RXN] synonym: "L-pipecolate:oxygen 1,6-oxidoreductase activity" EXACT [EC:1.5.3.7] synonym: "L-pipecolic acid oxidase activity" EXACT [EC:1.5.3.7] xref: EC:1.5.3.7 xref: GO:0050031 xref: MetaCyc:L-PIPECOLATE-OXIDASE-RXN is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0007385 name: L-rhamnonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H2O." [EC:4.2.1.90, MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN] synonym: "L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)" EXACT [EC:4.2.1.90] synonym: "L-rhamnonate hydro-lyase activity" EXACT [EC:4.2.1.90] xref: EC:4.2.1.90 xref: GO:0050032 xref: MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007386 name: L-rhamnono-1,4-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: L-rhamnono-1,4-lactone + H2O = L-rhamnonate." [EC:3.1.1.65, MetaCyc:L-RHAMNONO-1] synonym: "L-rhamno-gamma-lactonase activity" EXACT [EC:3.1.1.65] synonym: "L-rhamnono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.65] synonym: "L-rhamnono-gamma-lactonase activity" EXACT [EC:3.1.1.65] xref: EC:3.1.1.65 xref: GO:0050033 xref: MetaCyc:L-RHAMNONO-1 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007387 name: L-rhamnose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-rhamnofuranose + NAD+ = L-rhamno-1,4-lactone + NADH." [EC:1.1.1.173, MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN] synonym: "L-rhamnofuranose:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.173] xref: EC:1.1.1.173 xref: GO:0050034 xref: MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007388 name: L-sorbose oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-sorbose + O2 = 5-dehydro-D-fructose + H2O2." [EC:1.1.3.11, MetaCyc:L-SORBOSE-OXIDASE-RXN] synonym: "L-sorbose:oxygen 5-oxidoreductase activity" EXACT [EC:1.1.3.11] xref: EC:1.1.3.11 xref: GO:0050035 xref: MetaCyc:L-SORBOSE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007389 name: L-threonate 3-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-threonate + NAD+ = 3-dehydro-L-threonate + NADH." [EC:1.1.1.129, MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN] synonym: "L-threonate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.129] synonym: "L-threonic acid dehydrogenase activity" EXACT [EC:1.1.1.129] synonym: "threonate dehydrogenase activity" EXACT [EC:1.1.1.129] xref: EC:1.1.1.129 xref: GO:0050036 xref: MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007390 name: L-xylose 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-xylose + NADP+ = L-xylono-1,4-lactone + NADPH." [EC:1.1.1.113, MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN] synonym: "L-xylose dehydrogenase activity" EXACT [EC:1.1.1.113] synonym: "L-xylose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.113] synonym: "NADPH-xylose reductase activity" EXACT [EC:1.1.1.113] xref: EC:1.1.1.113 xref: GO:0050037 xref: MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007391 name: L-xylulose reductase activity namespace: molecular_function def: "Catalysis of the reaction: xylitol + NADP+ = L-xylulose + NADPH." [EC:1.1.1.10, MetaCyc:L-XYLULOSE-REDUCTASE-RXN] xref: EC:1.1.1.10 xref: GO:0050038 xref: MetaCyc:L-XYLULOSE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007392 name: lactaldehyde reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: propane-1,2-diol + NADP+ = L-lactaldehyde + NADPH." [EC:1.1.1.55, MetaCyc:LACTALDEHYDE-REDUCTASE-(NADPH)-RXN] synonym: "1,2-propanediol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.55] synonym: "lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.1.1.55] synonym: "NADP-1,2-propanediol dehydrogenase activity" EXACT [EC:1.1.1.55] synonym: "propane-1,2-diol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.55] synonym: "propanediol dehydrogenase activity" EXACT [EC:1.1.1.55] xref: EC:1.1.1.55 xref: GO:0050039 xref: MetaCyc:LACTALDEHYDE-REDUCTASE-(NADPH)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007393 name: lactate 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactate + O2 = acetate + CO2 + H2O." [EC:1.13.12.4, MetaCyc:LACTATE-2-MONOOXYGENASE-RXN] subset: gosubset_prok synonym: "(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.4] synonym: "L-lactate monooxygenase activity" EXACT [EC:1.13.12.4] synonym: "L-lactate-2-monooxygenase activity" EXACT [EC:1.13.12.4] synonym: "lactate monooxygenase activity" EXACT [EC:1.13.12.4] synonym: "lactate oxidase activity" EXACT [EC:1.13.12.4] synonym: "lactate oxidative decarboxylase activity" EXACT [EC:1.13.12.4] synonym: "lactate oxygenase activity" EXACT [EC:1.13.12.4] synonym: "lactic oxidase activity" EXACT [EC:1.13.12.4] synonym: "lactic oxygenase activity" EXACT [EC:1.13.12.4] xref: EC:1.13.12.4 xref: GO:0050040 xref: MetaCyc:LACTATE-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) [Term] id: CCO:F0007394 name: lactate aldolase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactate = formate + acetaldehyde." [EC:4.1.2.36, MetaCyc:LACTATE-ALDOLASE-RXN] synonym: "(S)-lactate acetaldehyde-lyase (formate-forming)" EXACT [EC:4.1.2.36] synonym: "(S)-lactate acetaldehyde-lyase activity" EXACT [EC:4.1.2.36] synonym: "lactate synthase activity" EXACT [EC:4.1.2.36] xref: EC:4.1.2.36 xref: GO:0050041 xref: MetaCyc:LACTATE-ALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007395 name: lactate-malate transhydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactate + oxaloacetate = pyruvate + malate." [EC:1.1.99.7, MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN] synonym: "(S)-lactate:oxaloacetate oxidoreductase activity" EXACT [EC:1.1.99.7] synonym: "malate-lactate transhydrogenase activity" EXACT [EC:1.1.99.7] xref: EC:1.1.99.7 xref: GO:0050042 xref: MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007396 name: lactate racemase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactate = (R)-lactate." [EC:5.1.2.1, MetaCyc:LACTATE-RACEMASE-RXN] synonym: "hydroxyacid racemase activity" EXACT [EC:5.1.2.1] synonym: "lactic acid racemase activity" EXACT [EC:5.1.2.1] synonym: "lacticoracemase activity" EXACT [EC:5.1.2.1] xref: EC:5.1.2.1 xref: GO:0050043 xref: MetaCyc:LACTATE-RACEMASE-RXN is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0007397 name: galactose-6-phosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate." [EC:5.3.1.26, MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN] subset: gosubset_prok synonym: "D-galactose-6-phosphate aldose-ketose-isomerase activity" EXACT [EC:5.3.1.26] synonym: "D-galactose-6-phosphate ketol-isomerase activity" EXACT [EC:5.3.1.26] xref: EC:5.3.1.26 xref: GO:0050044 xref: MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0007398 name: laminaribiose phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate." [EC:2.4.1.31, MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN] synonym: "3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.31] xref: EC:2.4.1.31 xref: GO:0050045 xref: MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0007399 name: lathosterol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol + O2 = cholesta-5,7-dien-3-beta-ol + H2O2." [EC:1.14.21.6, MetaCyc:LATHOSTEROL-OXIDASE-RXN] synonym: "5-DES" RELATED [EC:1.14.21.6] synonym: "5alpha-cholest-7-en-3beta-ol, NAD(P)H:oxygen 5-oxidoreductase activity" EXACT [EC:1.14.21.6] synonym: "delta7-sterol 5-desaturase activity" EXACT [EC:1.14.21.6] synonym: "delta7-sterol delta5-dehydrogenase activity" EXACT [EC:1.14.21.6] synonym: "delta7-sterol-C5(6)-desaturase activity" EXACT [EC:1.14.21.6] synonym: "lathosterol 5-desaturase activity" EXACT [EC:1.14.21.6] xref: EC:1.14.21.6 xref: GO:0050046 xref: MetaCyc:LATHOSTEROL-OXIDASE-RXN is_a: CCO:F0006310 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated [Term] id: CCO:F0007400 name: leucine 2,3-aminomutase activity namespace: molecular_function def: "Catalysis of the reaction: (2S)-alpha-leucine = (3R)-beta-leucine." [EC:5.4.3.7, MetaCyc:LEUCINE-2] synonym: "(2S)-alpha-leucine 2,3-aminomutase activity" EXACT [EC:5.4.3.7] xref: EC:5.4.3.7 xref: GO:0050047 xref: MetaCyc:LEUCINE-2 is_a: CCO:F0003430 ! intramolecular transferase activity, transferring amino groups [Term] id: CCO:F0007401 name: leucine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate." [EC:2.6.1.6, MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN] synonym: "L-leucine aminotransferase activity" EXACT [EC:2.6.1.6] synonym: "L-leucine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.6] synonym: "leucine 2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.6] synonym: "leucine aminotransferase activity" EXACT [] synonym: "leucine-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.6] xref: EC:2.6.1.6 xref: GO:0050048 xref: MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007402 name: leucine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH." [EC:1.4.1.9, MetaCyc:LEUCINE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "L-leucine dehydrogenase activity" EXACT [EC:1.4.1.9] synonym: "L-leucine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.9] synonym: "L-leucine:NAD+ oxidoreductase, deaminating" EXACT [EC:1.4.1.9] synonym: "LeuDH activity" EXACT [EC:1.4.1.9] xref: EC:1.4.1.9 xref: GO:0050049 xref: MetaCyc:LEUCINE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007403 name: leucine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-leucine = CoA + N-acetyl-L-leucine." [EC:2.3.1.66, MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:L-leucine N-acetyltransferase activity" EXACT [EC:2.3.1.66] synonym: "leucine acetyltransferase activity" EXACT [EC:2.3.1.66] xref: EC:2.3.1.66 xref: GO:0050050 xref: MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0007404 name: leukotriene-B4 20-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H2O = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O." [EC:1.14.13.30, MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN] synonym: "(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)" EXACT [EC:1.14.13.30] synonym: "leucotriene-B4 omega-hydroxylase activity" EXACT [EC:1.14.13.30] synonym: "leukotriene-B(4) 20-hydroxylase activity" EXACT [EC:1.14.13.30] synonym: "leukotriene-B(4) omega-hydroxylase activity" EXACT [EC:1.14.13.30] synonym: "leukotriene-B4 20-hydroxylase activity" EXACT [] synonym: "leukotriene-B4 omega-hydroxylase activity" EXACT [EC:1.14.13.30] synonym: "LTB(4) 20-hydroxylase activity" EXACT [EC:1.14.13.30] synonym: "LTB(4) omega-hydroxylase activity" EXACT [EC:1.14.13.30] synonym: "LTB4 20-hydroxylase activity" EXACT [EC:1.14.13.30] synonym: "LTB4 omega-hydroxylase activity" EXACT [EC:1.14.13.30] xref: EC:1.14.13.30 xref: GO:0050051 xref: MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007405 name: leukotriene-E4 20-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate + NADPH + O2 = 20-hydroxy-leucotriene E4 + NADP+ + H2O." [EC:1.14.13.34, MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN] synonym: "(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)" EXACT [EC:1.14.13.34] synonym: "leukotriene-E(4) omega-hydroxylase activity" EXACT [EC:1.14.13.34] synonym: "leukotriene-E4 omega-hydroxylase activity" EXACT [EC:1.14.13.34] synonym: "leukotriene-E4 w-hydroxylase activity" EXACT [] xref: EC:1.14.13.34 xref: GO:0050052 xref: MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007406 name: levansucrase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1)." [EC:2.4.1.10, MetaCyc:LEVANSUCRASE-RXN] subset: gosubset_prok synonym: "beta-2,6-fructan:D-glucose 1-fructosyltransferase activity" EXACT [EC:2.4.1.10] synonym: "beta-2,6-fructosyltransferase activity" EXACT [EC:2.4.1.10] synonym: "sucrose 6-fructosyl transferase activity" EXACT [EC:2.4.1.10] synonym: "sucrose 6-fructosyltransferase activity" EXACT [EC:2.4.1.10] synonym: "sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.10] xref: EC:2.4.1.10 xref: GO:0050053 xref: MetaCyc:LEVANSUCRASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007407 name: lignostilbene alpha beta-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethene + O2 = 2 vanillin." [EC:1.13.11.43, MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN] synonym: "1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)" EXACT [EC:1.13.11.43] synonym: "lignostilbene ab-dioxygenase activity" EXACT [] synonym: "lignostilbene alphabeta-dioxygenase activity" EXACT [EC:1.13.11.43] xref: EC:1.13.11.43 xref: GO:0050054 xref: MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007408 name: limonin-D-ring-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate." [EC:3.1.1.36, MetaCyc:LIMONIN-D-RING-LACTONASE-RXN] synonym: "limonin lactone hydrolase activity" EXACT [EC:3.1.1.36] synonym: "limonin-D-ring-lactone hydrolase activity" EXACT [EC:3.1.1.36] synonym: "limonoate-D-ring-lactone lactonohydrolase activity" EXACT [EC:3.1.1.36] xref: EC:3.1.1.36 xref: GO:0050055 xref: MetaCyc:LIMONIN-D-RING-LACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007409 name: linalool 8-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,7-dimethylocta-1,6-dien-3-ol + donor-H2 + O2 = (E)-3,7-dimethylocta-1,6-dien-3,8-diol + acceptor + H2O." [EC:1.14.99.28, MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN] subset: gosubset_prok synonym: "3,7-dimethylocta-1,6-dien-3-ol,hydrogen-donor:oxygen oxidoreductase (8-hydroxylating)" EXACT [EC:1.14.99.28] xref: EC:1.14.99.28 xref: GO:0050056 xref: MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007410 name: linamarin synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin." [EC:2.4.1.63, MetaCyc:LINAMARIN-SYNTHASE-RXN] synonym: "UDP glucose ketone cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.63] synonym: "UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.63] synonym: "UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.63] synonym: "UDPglucose:ketone cyanohydrin beta-glucosyltransferase activity" EXACT [EC:2.4.1.63] synonym: "uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase activity" EXACT [EC:2.4.1.63] synonym: "uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase activity" EXACT [EC:2.4.1.63] synonym: "uridine diphosphoglucose-ketone glucosyltransferase activity" EXACT [EC:2.4.1.63] xref: EC:2.4.1.63 xref: GO:0050057 xref: MetaCyc:LINAMARIN-SYNTHASE-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007411 name: linoleate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 9-cis,12-cis-octadecadienoate = 9-cis,11-trans-octadecadienoate." [EC:5.2.1.5, MetaCyc:LINOLEATE-ISOMERASE-RXN] synonym: "linoleate delta12-cis-delta11-trans-isomerase activity" EXACT [EC:5.2.1.5] synonym: "linoleic acid isomerase activity" EXACT [EC:5.2.1.5] xref: EC:5.2.1.5 xref: GO:0050058 xref: MetaCyc:LINOLEATE-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0007412 name: lombricine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine." [EC:2.7.3.5, MetaCyc:LOMBRICINE-KINASE-RXN] synonym: "ATP:lombricine N-phosphotransferase activity" EXACT [EC:2.7.3.5] xref: EC:2.7.3.5 xref: GO:0050059 xref: MetaCyc:LOMBRICINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0007413 name: long-chain-alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH." [EC:1.1.1.192, MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN] synonym: "fatty alcohol oxidoreductase activity" EXACT [EC:1.1.1.192] synonym: "long-chain alcohol dehydrogenase activity" EXACT [EC:1.1.1.192] synonym: "long-chain-alcohol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.192] xref: EC:1.1.1.192 xref: GO:0050060 xref: MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007414 name: long-chain-aldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+." [EC:1.2.1.48, MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN] synonym: "fatty aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.48] synonym: "long-chain aliphatic aldehyde dehydrogenase activity" EXACT [EC:1.2.1.48] synonym: "long-chain fatty aldehyde dehydrogenase activity" EXACT [EC:1.2.1.48] synonym: "long-chain-aldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.48] xref: EC:1.2.1.48 xref: GO:0050061 xref: MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN xref: UM-BBD_enzymeID:e0874 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007415 name: long-chain-fatty-acyl-CoA reductase activity namespace: molecular_function def: "Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH." [EC:1.2.1.50, MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN] subset: gosubset_prok synonym: "acyl coenzyme A reductase activity" EXACT [EC:1.2.1.50] synonym: "long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming)" EXACT [EC:1.2.1.50] xref: EC:1.2.1.50 xref: GO:0050062 xref: MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007416 name: low-density-lipoprotein-receptor kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine." [EC:2.7.11.29, MetaCyc:LOW-DENSITY-LIPOPROTEIN-KINASE-RXN] synonym: "[low-density lipoprotein receptor] kinase activity" EXACT [] synonym: "ATP:low-density-lipoprotein receptor-L-serine O-phosphotransferase activity" EXACT [EC:2.7.11.29] synonym: "ATP:low-density-lipoprotein-L-serine O-phosphotransferase activity" EXACT [EC:2.7.11.29] synonym: "LDL receptor kinase activity" EXACT [EC:2.7.11.29] synonym: "low-density lipoprotein receptor kinase activity" EXACT [EC:2.7.11.29] synonym: "low-density-lipoprotein kinase activity" BROAD [EC:2.7.11.29] synonym: "low-density-lipoprotein receptor kinase (phosphorylating) activity" EXACT [EC:2.7.11.29] synonym: "STK7" RELATED [EC:2.7.11.29] xref: EC:2.7.11.29 xref: GO:0050063 xref: MetaCyc:LOW-DENSITY-LIPOPROTEIN-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0007417 name: luteolin 7-O-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucuronate + luteolin = UDP + luteolin 7-O-beta-D-glucuronide." [EC:2.4.1.189, MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN] synonym: "LGT" RELATED [EC:2.4.1.189] synonym: "luteolin 7-O-glucoronosyltransferase activity" EXACT [] synonym: "UDP-glucuronate:luteolin 7-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.189] synonym: "UDPglucuronate:luteolin 7-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.189] synonym: "uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase activity" EXACT [EC:2.4.1.189] xref: EC:2.4.1.189 xref: GO:0050064 xref: MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0007418 name: lysine-pyruvate 6-transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine + pyruvate = 2-aminoadipate 6-semialdehyde + L-alanine." [EC:2.6.1.71, MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN] synonym: "L-lysine:pyruvate aminotransferase activity" EXACT [EC:2.6.1.71] synonym: "Lys-AT" RELATED [EC:2.6.1.71] synonym: "lysine--pyruvate 6-aminotransferase activity" EXACT [] synonym: "lysine-pyruvate aminotransferase activity" EXACT [EC:2.6.1.71] xref: EC:2.6.1.71 xref: GO:0050065 xref: MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN xref: MetaCyc:PWY-5324 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007419 name: lysine 2,3-aminomutase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate." [EC:5.4.3.2, MetaCyc:LYSINE-2] subset: gosubset_prok synonym: "L-lysine 2,3-aminomutase activity" EXACT [EC:5.4.3.2] xref: EC:5.4.3.2 xref: GO:0050066 xref: MetaCyc:LYSINE-2 is_a: CCO:F0003430 ! intramolecular transferase activity, transferring amino groups [Term] id: CCO:F0007420 name: lysine 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine + O2 = 5-aminopentanamide + CO2 + H2O." [EC:1.13.12.2, MetaCyc:LYSINE-2-MONOOXYGENASE-RXN] synonym: "L-lysine-2-monooxygenase activity" EXACT [EC:1.13.12.2] synonym: "L-lysine:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.2] synonym: "lysine monooxygenase activity" EXACT [EC:1.13.12.2] synonym: "lysine oxygenase activity" EXACT [EC:1.13.12.2] xref: EC:1.13.12.2 xref: GO:0050067 xref: MetaCyc:LYSINE-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) [Term] id: CCO:F0007421 name: lysine carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: carbamoyl phosphate + L-lysine = phosphate + L-homocitrulline." [EC:2.1.3.8, MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN] synonym: "carbamoyl-phosphate:L-lysine carbamoyltransferase activity" EXACT [EC:2.1.3.8] synonym: "lysine transcarbamylase activity" EXACT [EC:2.1.3.8] xref: EC:2.1.3.8 xref: GO:0050068 xref: MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0007422 name: lysine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH." [EC:1.4.1.15, MetaCyc:LYSINE-DEHYDROGENASE-RXN] synonym: "L-lysine:NAD+ oxidoreductase (deaminating, cyclizing)" EXACT [EC:1.4.1.15] xref: EC:1.4.1.15 xref: GO:0050069 xref: MetaCyc:LYSINE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007423 name: lysolecithin acylmutase activity namespace: molecular_function def: "Catalysis of the reaction: 2-lysolecithin = 3-lysolecithin." [EC:5.4.1.1, MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN] synonym: "lysolecithin 2,3-acylmutase activity" EXACT [EC:5.4.1.1] synonym: "lysolecithin migratase activity" RELATED [EC:5.4.1.1] xref: EC:5.4.1.1 xref: GO:0050070 xref: MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN is_a: CCO:F0003428 ! intramolecular transferase activity, transferring acyl groups [Term] id: CCO:F0007424 name: lysyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol." [EC:2.3.2.3, MetaCyc:LYSYLTRANSFERASE-RXN] subset: gosubset_prok synonym: "L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase activity" EXACT [EC:2.3.2.3] synonym: "L-lysyl-tRNA:phosphatidylglycerol O3-lysyltransferase activity" EXACT [EC:2.3.2.3] xref: EC:2.3.2.3 xref: GO:0050071 xref: MetaCyc:LYSYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0007425 name: m7G(5')pppN diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide." [EC:3.6.1.30, MetaCyc:M(7)G(5] synonym: "7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity" EXACT [EC:3.6.1.30] synonym: "decapase activity" RELATED [EC:3.6.1.30] synonym: "M(7)G(5')pppN pyrophosphatase activity" EXACT [] synonym: "m7G(5')pppN pyrophosphatase activity" EXACT [EC:3.6.1.30] xref: EC:3.6.1.30 xref: GO:0050072 xref: MetaCyc:M(7)G(5 is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0007426 name: macrolide 2'-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + oleandomycin = ADP + oleandomycin 2'-O-phosphate." [EC:2.7.1.136, MetaCyc:MACROLIDE-2] synonym: "ATP:macrolide 2'-O-phosphotransferase activity" EXACT [EC:2.7.1.136] xref: EC:2.7.1.136 xref: GO:0050073 xref: MetaCyc:MACROLIDE-2 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007427 name: malate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA." [EC:6.2.1.9, MetaCyc:MALATE--COA-LIGASE-RXN] subset: gosubset_prok synonym: "malate thiokinase activity" RELATED [EC:6.2.1.9] synonym: "malate:CoA ligase (ADP-forming)" EXACT [EC:6.2.1.9] synonym: "malyl coenzyme A synthetase activity" EXACT [EC:6.2.1.9] synonym: "malyl-CoA synthetase activity" EXACT [EC:6.2.1.9] xref: EC:6.2.1.9 xref: GO:0050074 xref: MetaCyc:MALATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007428 name: maleate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-malate = maleate + H2O." [EC:4.2.1.31, MetaCyc:MALEATE-HYDRATASE-RXN] synonym: "(R)-malate hydro-lyase (maleate-forming)" EXACT [EC:4.2.1.31] synonym: "(R)-malate hydro-lyase activity" EXACT [EC:4.2.1.31] synonym: "D-malate hydro-lyase activity" EXACT [EC:4.2.1.31] synonym: "malease activity" EXACT [EC:4.2.1.31] xref: EC:4.2.1.31 xref: GO:0050075 xref: MetaCyc:MALEATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007429 name: maleate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: maleate = fumarate." [EC:5.2.1.1, MetaCyc:MALEATE-ISOMERASE-RXN] subset: gosubset_prok synonym: "maleate cis-trans-isomerase activity" EXACT [EC:5.2.1.1] xref: EC:5.2.1.1 xref: GO:0050076 xref: MetaCyc:MALEATE-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0007430 name: maleylpyruvate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate." [EC:5.2.1.4, MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN] subset: gosubset_prok synonym: "3-maleylpyruvate cis-trans-isomerase activity" EXACT [EC:5.2.1.4] xref: EC:5.2.1.4 xref: GO:0050077 xref: MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0007431 name: malonate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA." [EC:2.8.3.3, MetaCyc:MALONATE-COA-TRANSFERASE-RXN] synonym: "acetyl-CoA:malonate CoA-transferase activity" EXACT [EC:2.8.3.3] synonym: "malonate coenzyme A-transferase activity" EXACT [EC:2.8.3.3] xref: EC:2.8.3.3 xref: GO:0050078 xref: MetaCyc:MALONATE-COA-TRANSFERASE-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0007432 name: acetylenecarboxylate hydratase activity, producing 3-oxopropanoate namespace: molecular_function def: "Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O." [EC:4.2.1.27, MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN] comment: Note that this function was formerly EC:4.2.1.71. synonym: "3-oxopropanoate hydro-lyase (propynoate-forming)" EXACT [EC:4.2.1.27] synonym: "3-oxopropanoate hydro-lyase activity" EXACT [EC:4.2.1.27] synonym: "acetylenecarboxylate hydratase activity" BROAD [] synonym: "acetylenecarboxylate hydratase activity, producing malonate-semialdehyde" EXACT [] synonym: "acetylenemonocarboxylate hydrase activity" EXACT [EC:4.2.1.27] synonym: "acetylenemonocarboxylate hydratase activity" BROAD [] synonym: "acetylmonocarboxylic acid hydrase activity" EXACT [EC:4.2.1.27] synonym: "alkynoate hydratase activity" BROAD [] synonym: "malonate-semialdehyde dehydratase activity" EXACT [] xref: EC:4.2.1.27 xref: GO:0047607 xref: GO:0050079 xref: MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007433 name: malonyl-CoA decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2." [EC:4.1.1.9, MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN] subset: gosubset_prok synonym: "malonyl coenzyme A decarboxylase activity" EXACT [EC:4.1.1.9] synonym: "malonyl-CoA carboxy-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.1.9] synonym: "malonyl-CoA carboxy-lyase activity" EXACT [EC:4.1.1.9] xref: EC:4.1.1.9 xref: GO:0050080 xref: MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007434 name: maltose-6'-phosphate glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate." [EC:3.2.1.122, MetaCyc:MALTOSE-6] subset: gosubset_prok synonym: "maltose-6'-phosphate 6-phosphoglucohydrolase activity" EXACT [EC:3.2.1.122] synonym: "phospho-alpha-glucosidase activity" EXACT [EC:3.2.1.122] xref: EC:3.2.1.122 xref: GO:0050081 xref: MetaCyc:MALTOSE-6 is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0007435 name: maltose phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate." [EC:2.4.1.8, MetaCyc:MALTOSE-PHOSPHORYLASE-RXN] subset: gosubset_prok synonym: "maltose:phosphate 1-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.8] xref: EC:2.4.1.8 xref: GO:0050082 xref: MetaCyc:MALTOSE-PHOSPHORYLASE-RXN is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0007436 name: malyl-CoA lyase activity namespace: molecular_function def: "Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate." [EC:4.1.3.24, MetaCyc:MALYL-COA-LYASE-RXN] synonym: "(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.24] synonym: "(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase activity" EXACT [EC:4.1.3.24] synonym: "malyl-coenzyme A lyase activity" EXACT [EC:4.1.3.24] xref: EC:4.1.3.24 xref: GO:0050083 xref: MetaCyc:MALYL-COA-LYASE-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0007437 name: mannitol-1-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannitol 1-phosphate + H2O = D-mannitol + phosphate." [EC:3.1.3.22, MetaCyc:MANNITOL-1-PHOSPHATASE-RXN] synonym: "D-mannitol-1-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.22] synonym: "mannitol-1-phosphate phosphatase activity" EXACT [EC:3.1.3.22] xref: EC:3.1.3.22 xref: GO:0050084 xref: MetaCyc:MANNITOL-1-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007438 name: mannitol 2-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: D-mannitol + NADP+ = D-fructose + NADPH." [EC:1.1.1.138, MetaCyc:MANNITOL-2-DEHYDROGENASE-(NADP+)-RXN] synonym: "D-mannitol:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.138] synonym: "NADP-dependent mannitol dehydrogenase activity" EXACT [EC:1.1.1.138] xref: EC:1.1.1.138 xref: GO:0050085 xref: MetaCyc:MANNITOL-2-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007439 name: mannitol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH." [EC:1.1.1.67, MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "D-mannitol dehydrogenase activity" EXACT [EC:1.1.1.67] synonym: "D-mannitol:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.67] xref: EC:1.1.1.67 xref: GO:0050086 xref: MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007440 name: mannitol dehydrogenase (cytochrome) activity namespace: molecular_function def: "Catalysis of the reaction: D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c." [EC:1.1.2.2, MetaCyc:MANNITOL-DEHYDROGENASE-(CYTOCHROME)-RXN] synonym: "D-mannitol:ferricytochrome-c 2-oxidoreductase activity" EXACT [EC:1.1.2.2] synonym: "polyol dehydrogenase activity" BROAD [EC:1.1.2.2] xref: EC:1.1.2.2 xref: GO:0050087 xref: MetaCyc:MANNITOL-DEHYDROGENASE-(CYTOCHROME)-RXN is_a: CCO:F0003456 ! oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor [Term] id: CCO:F0007441 name: mannose-6-phosphate 6-reductase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + NADPH." [EC:1.1.1.224, MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN] synonym: "6-phosphomannose reductase activity" EXACT [EC:1.1.1.224] synonym: "D-mannitol-1-phosphate:NADP+ 6-oxidoreductase activity" EXACT [EC:1.1.1.224] synonym: "mannose-6-phosphate reductase activity" EXACT [EC:1.1.1.224] synonym: "NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity" EXACT [EC:1.1.1.224] synonym: "NADPH-dependent M6P reductase activity" EXACT [EC:1.1.1.224] synonym: "NADPH-dependent mannose 6-phosphate reductase activity" EXACT [EC:1.1.1.224] synonym: "NADPH-mannose-6-P reductase activity" EXACT [EC:1.1.1.224] xref: EC:1.1.1.224 xref: GO:0050088 xref: MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007442 name: mannose isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannose = D-fructose." [EC:5.3.1.7, MetaCyc:MANNOSE-ISOMERASE-RXN] synonym: "D-mannose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.7] synonym: "D-mannose isomerase activity" EXACT [EC:5.3.1.7] synonym: "D-mannose ketol-isomerase activity" EXACT [EC:5.3.1.7] xref: EC:5.3.1.7 xref: GO:0050089 xref: MetaCyc:MANNOSE-ISOMERASE-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0007443 name: mannuronate reductase activity namespace: molecular_function def: "Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+." [EC:1.1.1.131, MetaCyc:MANNURONATE-REDUCTASE-RXN] synonym: "D-mannonate:NAD(P)+ 6-oxidoreductase activity" EXACT [EC:1.1.1.131] synonym: "D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming))" EXACT [EC:1.1.1.131] synonym: "mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase activity" EXACT [EC:1.1.1.131] synonym: "mannonate dehydrogenase (NAD(P)+)" EXACT [EC:1.1.1.131] synonym: "mannonate dehydrogenase activity" EXACT [EC:1.1.1.131] xref: EC:1.1.1.131 xref: GO:0050090 xref: MetaCyc:MANNURONATE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007444 name: melilotate 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NADH + O2 = 3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O." [EC:1.14.13.4, MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN] synonym: "2-hydroxyphenylpropionate hydroxylase activity" EXACT [EC:1.14.13.4] synonym: "2-hydroxyphenylpropionic hydroxylase activity" EXACT [EC:1.14.13.4] synonym: "3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.4] synonym: "melilotate hydroxylase activity" EXACT [] synonym: "melilotic hydroxylase activity" EXACT [EC:1.14.13.4] xref: EC:1.14.13.4 xref: GO:0050091 xref: MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007445 name: meso-tartrate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: meso-tartrate + NAD+ = dihydroxyfumarate + NADH." [EC:1.3.1.7, MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN] synonym: "meso-tartrate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.7] xref: EC:1.3.1.7 xref: GO:0050092 xref: MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007446 name: methanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: methanol + NAD+ = formaldehyde + NADH." [EC:1.1.1.244, MetaCyc:METHANOL-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "methanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.244] xref: EC:1.1.1.244 xref: GO:0050093 xref: MetaCyc:METHANOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007447 name: methionine-glyoxylate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine." [EC:2.6.1.73, MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN] synonym: "L-methionine:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.73] synonym: "methionine-glyoxylate aminotransferase activity" EXACT [EC:2.6.1.73] synonym: "MGAT activity" EXACT [EC:2.6.1.73] xref: EC:2.6.1.73 xref: GO:0050094 xref: MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007448 name: methionine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-methionine = 3-methylthiopropanamine + CO2." [EC:4.1.1.57, MetaCyc:METHIONINE-DECARBOXYLASE-RXN] synonym: "L-methionine carboxy-lyase (3-methylthiopropanamine-forming)" EXACT [EC:4.1.1.57] synonym: "L-methionine carboxy-lyase activity" EXACT [EC:4.1.1.57] synonym: "L-methionine decarboxylase activity" EXACT [EC:4.1.1.57] xref: EC:4.1.1.57 xref: GO:0050095 xref: MetaCyc:METHIONINE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007449 name: methylaspartate ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-threo-3-methylaspartate = mesaconate + NH3." [EC:4.3.1.2, MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN] subset: gosubset_prok synonym: "3-methylaspartase activity" EXACT [EC:4.3.1.2] synonym: "beta-methylaspartase activity" EXACT [EC:4.3.1.2] synonym: "L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)" EXACT [EC:4.3.1.2] synonym: "L-threo-3-methylaspartate ammonia-lyase activity" EXACT [EC:4.3.1.2] xref: EC:4.3.1.2 xref: GO:0050096 xref: MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0007450 name: methylaspartate mutase activity namespace: molecular_function def: "Catalysis of the reaction: L-threo-3-methylaspartate = L-glutamate." [EC:5.4.99.1, MetaCyc:METHYLASPARTATE-MUTASE-RXN] subset: gosubset_prok synonym: "b-methylaspartate-glutamate mutase activity" EXACT [EC:5.4.99.1] synonym: "beta-methylaspartate-glutamate mutase activity" EXACT [EC:5.4.99.1] synonym: "glutamate isomerase activity" EXACT [EC:5.4.99.1] synonym: "glutamate mutase activity" EXACT [EC:5.4.99.1] synonym: "glutamic acid isomerase activity" EXACT [EC:5.4.99.1] synonym: "glutamic acid mutase activity" EXACT [EC:5.4.99.1] synonym: "glutamic isomerase activity" EXACT [EC:5.4.99.1] synonym: "glutamic mutase activity" EXACT [EC:5.4.99.1] synonym: "L-threo-3-methylaspartate carboxy-aminomethylmutase activity" EXACT [EC:5.4.99.1] synonym: "methylaspartic acid mutase activity" EXACT [EC:5.4.99.1] xref: EC:5.4.99.1 xref: GO:0050097 xref: MetaCyc:METHYLASPARTATE-MUTASE-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0007451 name: methylguanidinase activity namespace: molecular_function def: "Catalysis of the reaction: methylguanidine + H2O = methylamine + urea." [EC:3.5.3.16, MetaCyc:METHYLGUANIDINASE-RXN] synonym: "methylguanidine amidinohydrolase activity" EXACT [EC:3.5.3.16] synonym: "methylguanidine hydrolase activity" EXACT [EC:3.5.3.16] xref: EC:3.5.3.16 xref: GO:0050098 xref: MetaCyc:METHYLGUANIDINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007452 name: methylglutamate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N-methyl-L-glutamate + acceptor + H2O = L-glutamate + formaldehyde + reduced acceptor." [EC:1.5.99.5, MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN] synonym: "N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating)" EXACT [EC:1.5.99.5] synonym: "N-methyl-L-glutamate:acceptor oxidoreductase (demethylating)" EXACT [EC:1.5.99.5] synonym: "N-methylglutamate dehydrogenase activity" EXACT [EC:1.5.99.5] xref: EC:1.5.99.5 xref: GO:0050099 xref: MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0007453 name: methylitaconate delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: methylitaconate = dimethylmaleate." [EC:5.3.3.6, MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN] synonym: "methylitaconate D-isomerase activity" EXACT [] synonym: "methylitaconate delta2-delta3-isomerase activity" EXACT [EC:5.3.3.6] synonym: "methylitaconate isomerase activity" EXACT [EC:5.3.3.6] xref: EC:5.3.3.6 xref: GO:0050100 xref: MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0007454 name: mimosinase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate + H2O = 3-hydroxy-4H-pyrid-4-one + L-serine." [EC:3.5.1.61, MetaCyc:MIMOSINASE-RXN] synonym: "mimosine amidohydrolase activity" EXACT [EC:3.5.1.61] xref: EC:3.5.1.61 xref: GO:0050101 xref: MetaCyc:MIMOSINASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007455 name: cellodextrin phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate." [EC:2.4.1.49, MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN] subset: gosubset_prok synonym: "1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.49] synonym: "beta-1,4-oligoglucan:orthophosphate glucosyltransferase activity" EXACT [EC:2.4.1.49] xref: EC:2.4.1.49 xref: GO:0050102 xref: MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0007456 name: dextrin dextranase activity namespace: molecular_function def: "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1)." [EC:2.4.1.2, MetaCyc:DEXTRIN-DEXTRANASE-RXN] synonym: "1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.2] synonym: "dextran dextrinase activity" EXACT [EC:2.4.1.2] synonym: "dextrin 6-glucosyltransferase activity" EXACT [EC:2.4.1.2] xref: EC:2.4.1.2 xref: GO:0050103 xref: MetaCyc:DEXTRIN-DEXTRANASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007457 name: L-gulonate 3-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-gulonate + NAD+ = 3-dehydro-L-gulonate + NADH." [EC:1.1.1.45, MetaCyc:L-GULONATE-3-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "L-3-aldonate dehydrogenase activity" EXACT [EC:1.1.1.45] synonym: "L-3-aldonic dehydrogenase activity" EXACT [EC:1.1.1.45] synonym: "L-3-hydroxyacid dehydrogenase activity" EXACT [EC:1.1.1.45] synonym: "L-beta-hydroxy-acid-NAD-oxidoreductase activity" EXACT [EC:1.1.1.45] synonym: "L-beta-hydroxyacid dehydrogenase activity" EXACT [EC:1.1.1.45] synonym: "L-gulonate:NAD+ 3-oxidoreductase activity" EXACT [EC:1.1.1.45] synonym: "L-gulonic acid dehydrogenase activity" EXACT [EC:1.1.1.45] xref: EC:1.1.1.45 xref: GO:0050104 xref: MetaCyc:L-GULONATE-3-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007458 name: L-gulonolactone oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2." [EC:1.1.3.8, MetaCyc:L-GULONOLACTONE-OXIDASE-RXN] subset: gosubset_prok synonym: "GLO activity" EXACT [EC:1.1.3.8] synonym: "L-gulono-1,4-lactone:oxygen 3-oxidoreductase activity" EXACT [EC:1.1.3.8] synonym: "L-gulono-gamma-lactone oxidase activity" EXACT [EC:1.1.3.8] synonym: "L-gulono-gamma-lactone:O2 oxidoreductase activity" EXACT [EC:1.1.3.8] synonym: "L-gulono-gamma-lactone:oxidoreductase activity" EXACT [EC:1.1.3.8] xref: EC:1.1.3.8 xref: GO:0050105 xref: MetaCyc:L-GULONOLACTONE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007459 name: monomethyl-sulfatase activity namespace: molecular_function def: "Catalysis of the reaction: monomethyl sulfate + H2O = methanol + SO4(2-) (sulfate)." [EC:3.1.6.16, MetaCyc:MONOMETHYL-SULFATASE-RXN] synonym: "monomethyl-sulfate sulfohydrolase activity" EXACT [EC:3.1.6.16] synonym: "monomethyl-sulphatase activity" EXACT [] xref: EC:3.1.6.16 xref: GO:0050106 xref: MetaCyc:MONOMETHYL-SULFATASE-RXN is_a: CCO:F0001945 ! sulfuric ester hydrolase activity [Term] id: CCO:F0007460 name: monoterpenol O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester." [EC:2.3.1.69, MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:monoterpenol O-acetyltransferase activity" EXACT [EC:2.3.1.69] synonym: "menthol transacetylase activity" NARROW [EC:2.3.1.69] xref: EC:2.3.1.69 xref: GO:0050107 xref: MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0007461 name: monoterpenyl-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate." [EC:3.1.7.3, MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN] synonym: "bornyl diphosphate hydrolase activity" EXACT [EC:3.1.7.3] synonym: "bornyl pyrophosphate hydrolase activity" EXACT [EC:3.1.7.3] synonym: "monoterpenyl-diphosphate diphosphohydrolase activity" EXACT [EC:3.1.7.3] synonym: "monoterpenyl-pyrophosphatase activity" EXACT [] xref: EC:3.1.7.3 xref: GO:0050108 xref: MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN is_a: CCO:F0003364 ! diphosphoric monoester hydrolase activity [Term] id: CCO:F0007462 name: morphine 6-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+." [EC:1.1.1.218, MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "morphine:NAD(P)+ 6-oxidoreductase activity" EXACT [EC:1.1.1.218] synonym: "naloxone reductase activity" EXACT [EC:1.1.1.218] synonym: "reductase, naloxone" EXACT [EC:1.1.1.218] xref: EC:1.1.1.218 xref: GO:0050109 xref: MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007463 name: mucinaminylserine mucinaminidase activity namespace: molecular_function def: "Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine." [EC:3.2.1.110, MetaCyc:MUCINAMINYLSERINE-MUCINAMINIDASE-RXN] synonym: "D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase activity" EXACT [EC:3.2.1.110] synonym: "endo-alpha-N-acetyl-D-galactosaminidase activity" EXACT [EC:3.2.1.110] synonym: "endo-alpha-N-acetylgalactosaminidase" BROAD [EC:3.2.1.110] xref: EC:3.2.1.110 xref: GO:0050110 xref: MetaCyc:MUCINAMINYLSERINE-MUCINAMINIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007464 name: mycocerosate synthase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H+ = multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+." [EC:2.3.1.111, MetaCyc:MYCOCEROSATE-SYNTHASE-RXN] synonym: "acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)" EXACT [EC:2.3.1.111] synonym: "mycocerosic acid synthase activity" EXACT [EC:2.3.1.111] xref: EC:2.3.1.111 xref: GO:0050111 xref: MetaCyc:MYCOCEROSATE-SYNTHASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007465 name: inositol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH." [EC:1.1.1.18, MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "myo-inositol 2-dehydrogenase activity" EXACT [] xref: EC:1.1.1.18 xref: GO:0050112 xref: MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN is_a: CCO:F0000511 ! aldo-keto reductase activity [Term] id: CCO:F0007466 name: inositol oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: myo-inositol + O2 = D-glucuronate + H2O." [EC:1.13.99.1, MetaCyc:MYO-INOSITOL-OXYGENASE-RXN] synonym: "meso-inositol oxygenase activity" EXACT [EC:1.13.99.1] synonym: "MOO activity" EXACT [EC:1.13.99.1] synonym: "myo-inositol oxygenase activity" EXACT [] synonym: "myo-inositol:oxygen oxidoreductase activity" EXACT [EC:1.13.99.1] xref: EC:1.13.99.1 xref: GO:0050113 xref: MetaCyc:MYO-INOSITOL-OXYGENASE-RXN is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Term] id: CCO:F0007467 name: myo-inosose-2 dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3,5/4-trihydroxycyclohexa-1,2-dione + H2O." [EC:4.2.1.44, MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN] synonym: "2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)" EXACT [EC:4.2.1.44] synonym: "2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase activity" EXACT [EC:4.2.1.44] synonym: "inosose 2,3-dehydratase activity" EXACT [EC:4.2.1.44] synonym: "ketoinositol dehydratase activity" EXACT [EC:4.2.1.44] xref: EC:4.2.1.44 xref: GO:0050114 xref: MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007468 name: myosin-light-chain-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate." [EC:3.1.3.53, MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN] synonym: "[Myosin light-chain]-phosphatase activity" EXACT [] synonym: "myosin light chain kinase phosphatase activity" EXACT [EC:3.1.3.53] synonym: "myosin light-chain kinase phosphatase activity" RELATED [EC:3.1.3.53] synonym: "myosin-light-chain phosphatase activity" EXACT [EC:3.1.3.53] synonym: "myosin-light-chain-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.53] synonym: "protein phosphatase 2A" RELATED [EC:3.1.3.53] xref: EC:3.1.3.53 xref: GO:0050115 xref: MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007469 name: N,N-dimethylformamidase activity namespace: molecular_function def: "Catalysis of the reaction: N,N-dimethylformamide + H2O = dimethylamine + formate." [EC:3.5.1.56, MetaCyc:N] synonym: "dimethylformamidase activity" EXACT [EC:3.5.1.56] synonym: "DMFase activity" EXACT [EC:3.5.1.56] synonym: "N,N-dimethylformamide amidohydrolase activity" EXACT [EC:3.5.1.56] xref: EC:3.5.1.56 xref: GO:0050116 xref: MetaCyc:N is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007470 name: N-acetyl-beta-alanine deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-beta-alanine + H2O = acetate + beta-alanine." [EC:3.5.1.21, MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN] synonym: "N-acetyl-beta-alanine amidohydrolase activity" EXACT [EC:3.5.1.21] xref: EC:3.5.1.21 xref: GO:0050117 xref: MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0007471 name: N-acetyldiaminopimelate deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-LL2,6-diaminoheptanedioate + H2O = acetate + LL2,6-diaminoheptanedioate." [EC:3.5.1.47, MetaCyc:N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN] subset: gosubset_prok synonym: "6-N-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity" EXACT [EC:3.5.1.47] synonym: "N-acetyl-L-diaminopimelic acid deacylase activity" EXACT [EC:3.5.1.47] synonym: "N-acetyl-LL-diaminopimelate deacylase activity" EXACT [EC:3.5.1.47] synonym: "N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity" EXACT [EC:3.5.1.47] xref: EC:3.5.1.47 xref: GO:0050118 xref: MetaCyc:N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0007472 name: N-acetylglucosamine deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-D-glucosamine + H2O = D-glucosamine + acetate." [EC:3.5.1.33, MetaCyc:N-ACETYLGLUCOSAMINE-DEACETYLASE-RXN] synonym: "acetylaminodeoxyglucose acetylhydrolase activity" EXACT [EC:3.5.1.33] synonym: "N-acetyl-D-glucosamine amidohydrolase activity" EXACT [EC:3.5.1.33] synonym: "N-acetyl-D-glucosaminyl N-deacetylase activity" EXACT [EC:3.5.1.33] xref: EC:3.5.1.33 xref: GO:0050119 xref: MetaCyc:N-ACETYLGLUCOSAMINE-DEACETYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is_a: CCO:F0004136 ! deacetylase activity [Term] id: CCO:F0007473 name: N-acetylhexosamine 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NAD+ + N-acetyl-D-glucosamine = NADH + N-acetyl-D-glucosaminate." [EC:1.1.1.240, MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN] synonym: "N-acetyl-D-hexosamine dehydrogenase activity" EXACT [EC:1.1.1.240] synonym: "N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.240] synonym: "N-acetylhexosamine dehydrogenase activity" EXACT [EC:1.1.1.240] xref: EC:1.1.1.240 xref: GO:0050120 xref: MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007474 name: N-acylglucosamine 2-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine." [EC:5.1.3.8, MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN] subset: gosubset_prok synonym: "acylglucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] synonym: "GlcNAc 2-epimerase activity" EXACT [EC:5.1.3.8] synonym: "N-acetyl-D-glucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] synonym: "N-acetylglucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] synonym: "N-acyl-D-glucosamine 2-epimerase activity" EXACT [EC:5.1.3.8] xref: EC:5.1.3.8 xref: GO:0050121 xref: MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007475 name: N-acylhexosamine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + O2 + N-acetyl-D-glucosamine = H2O2 + N-acetyl-D-glucosaminate." [EC:1.1.3.29, MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN] synonym: "N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.29] synonym: "N-acyl-D-hexosamine oxidase activity" EXACT [EC:1.1.3.29] synonym: "N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity" EXACT [EC:1.1.3.29] xref: EC:1.1.3.29 xref: GO:0050122 xref: MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007476 name: N-acylmannosamine 1-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N-acyl-D-mannosamine + NAD+ = N-acyl-D-mannosaminolactone + NADH." [EC:1.1.1.233, MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "N-acetyl-D-mannosamine dehydrogenase activity" EXACT [EC:1.1.1.233] synonym: "N-acyl-D-mannosamine dehydrogenase activity" EXACT [EC:1.1.1.233] synonym: "N-acyl-D-mannosamine:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.233] synonym: "N-acylmannosamine dehydrogenase activity" EXACT [EC:1.1.1.233] xref: EC:1.1.1.233 xref: GO:0050123 xref: MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007477 name: N-acylneuraminate-9-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate." [EC:3.1.3.29, MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN] subset: gosubset_prok synonym: "acylneuraminate 9-phosphatase activity" EXACT [EC:3.1.3.29] synonym: "N-acylneuraminate-9-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.29] synonym: "N-acylneuraminic (sialic) acid 9-phosphatase activity" EXACT [EC:3.1.3.29] synonym: "N-acylneuraminic acid 9-phosphate phosphatase activity" EXACT [EC:3.1.3.29] xref: EC:3.1.3.29 xref: GO:0050124 xref: MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007478 name: N-benzyloxycarbonylglycine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-benzyloxycarbonylglycine + H2O = benzyl alcohol + CO2 + glycine." [EC:3.5.1.58, MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN] synonym: "benzyloxycarbonylglycine hydrolase activity" EXACT [EC:3.5.1.58] synonym: "N-benzyloxycarbonylglycine urethanehydrolase activity" EXACT [EC:3.5.1.58] synonym: "nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity" EXACT [EC:3.5.1.58] synonym: "nalpha-benzyloxycarbonyl amino acid urethane hydrolase I" RELATED [EC:3.5.1.58] synonym: "nalpha-carbobenzoxyamino acid amidohydrolase activity" EXACT [EC:3.5.1.58] xref: EC:3.5.1.58 xref: GO:0050125 xref: MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007479 name: N-carbamoylputrescine amidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N-carbamoylputrescine = NH3 + CO2 + putrescine." [EC:3.5.1.53, MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN] synonym: "carbamoylputrescine hydrolase activity" EXACT [EC:3.5.1.53] synonym: "N-carbamoylputrescine amidohydrolase activity" EXACT [EC:3.5.1.53] synonym: "NCP" RELATED [EC:3.5.1.53] xref: EC:3.5.1.53 xref: GO:0050126 xref: MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007480 name: N-carbamoylsarcosine amidase activity namespace: molecular_function def: "Catalysis of the reaction: N-carbamoylsarcosine + H2O = sarcosine + CO2 + NH3." [EC:3.5.1.59, MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN] subset: gosubset_prok synonym: "carbamoylsarcosine amidase activity" EXACT [EC:3.5.1.59] synonym: "CSHase activity" EXACT [EC:3.5.1.59] synonym: "N-carbamoylsarcosine amidohydrolase activity" EXACT [EC:3.5.1.59] xref: EC:3.5.1.59 xref: GO:0050127 xref: MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007481 name: N-feruloylglycine deacylase activity namespace: molecular_function def: "Catalysis of the reaction: N-feruloylglycine + H2O = ferulate + glycine." [EC:3.5.1.71, MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN] synonym: "N-feruloylglycine amidohydrolase activity" EXACT [EC:3.5.1.71] synonym: "N-feruloylglycine hydrolase activity" EXACT [EC:3.5.1.71] xref: EC:3.5.1.71 xref: GO:0050128 xref: MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007482 name: N-formylglutamate deformylase activity namespace: molecular_function def: "Catalysis of the reaction: N-formyl-L-glutamate + H2O = formate + L-glutamate." [EC:3.5.1.68, MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN] subset: gosubset_prok synonym: "beta-citryl-L-glutamate amidase activity" EXACT [EC:3.5.1.68] synonym: "beta-citryl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.68] synonym: "beta-citryl-L-glutamate hydrolase activity" EXACT [EC:3.5.1.68] synonym: "beta-citryl-L-glutamate-hydrolyzing enzyme" RELATED [EC:3.5.1.68] synonym: "beta-citrylglutamate amidase activity" EXACT [EC:3.5.1.68] synonym: "formylglutamate deformylase activity" EXACT [EC:3.5.1.68] synonym: "N-formyl-L-glutamate amidohydrolase activity" EXACT [EC:3.5.1.68] synonym: "N-formylglutamate hydrolase activity" EXACT [EC:3.5.1.68] xref: EC:3.5.1.68 xref: GO:0050129 xref: MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007483 name: N-methyl-2-oxoglutaramate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-methyl-2-oxoglutaramate + H2O = 2-oxoglutarate + methylamine." [EC:3.5.1.36, MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN] synonym: "5-hydroxy-N-methylpyroglutamate synthase activity" EXACT [EC:3.5.1.36] synonym: "N-methyl-2-oxoglutaramate methylamidohydrolase activity" EXACT [EC:3.5.1.36] xref: EC:3.5.1.36 xref: GO:0050130 xref: MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007484 name: N-methyl-L-amino-acid oxidase activity namespace: molecular_function def: "Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2." [EC:1.5.3.2, MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN] synonym: "N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.2] synonym: "N-methylamino acid oxidase activity" EXACT [EC:1.5.3.2] xref: EC:1.5.3.2 xref: GO:0050131 xref: MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0007485 name: N-methylalanine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N-methyl-L-alanine + H2O + NADP+ = pyruvate + methylamine + NADPH." [EC:1.4.1.17, MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN] synonym: "N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating)" EXACT [EC:1.4.1.17] xref: EC:1.4.1.17 xref: GO:0050132 xref: MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007486 name: N6-hydroxylysine O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + N6-hydroxy-L-lysine = CoA + N6-acetyl-N6-hydroxy-L-lysine." [EC:2.3.1.102, MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase activity" EXACT [EC:2.3.1.102] synonym: "acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase activity" EXACT [EC:2.3.1.102] synonym: "N(6)-hydroxylysine acetylase activity" EXACT [EC:2.3.1.102] synonym: "N6-hydroxylysine acetylase activity" EXACT [EC:2.3.1.102] synonym: "N6-hydroxylysine:acetyl CoA N6-transacetylase activity" EXACT [EC:2.3.1.102] xref: EC:2.3.1.102 xref: GO:0050133 xref: MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0007487 name: N6-methyl-lysine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: N6-methyl-L-lysine + H2O + O2 = L-lysine + formaldehyde + H2O2." [EC:1.5.3.4, MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN] synonym: "6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.4] synonym: "epsilon-alkyl-L-lysine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.4] synonym: "epsilon-alkyllysinase activity" EXACT [EC:1.5.3.4] synonym: "epsilon-N-methyllysine demethylase activity" EXACT [EC:1.5.3.4] synonym: "N(6)-methyllysine oxidase activity" EXACT [EC:1.5.3.4] synonym: "N6-methyl-L-lysine:oxygen oxidoreductase (demethylating)" EXACT [EC:1.5.3.4] synonym: "N6-methyllysine oxidase activity" EXACT [EC:1.5.3.4] xref: EC:1.5.3.4 xref: GO:0050134 xref: MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0007488 name: NAD(P)+ nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + H2O = ADPribose(P) + nicotinamide." [EC:3.2.2.6, MetaCyc:NAD(P)(+)-NUCLEOSIDASE-RXN] synonym: "NAD(P) nucleosidase activity" EXACT [] synonym: "NAD(P)(+) nucleosidase activity" EXACT [] synonym: "NAD(P)+ glycohydrolase activity" EXACT [EC:3.2.2.6] synonym: "NAD(P)ase activity" EXACT [EC:3.2.2.6] synonym: "nicotinamide adenine dinucleotide (phosphate) glycohydrolase activity" EXACT [EC:3.2.2.6] synonym: "nicotinamide adenine dinucleotide (phosphate) nucleosidase activity" EXACT [EC:3.2.2.6] synonym: "triphosphopyridine nucleotidase activity" EXACT [EC:3.2.2.6] xref: EC:3.2.2.6 xref: GO:0050135 xref: MetaCyc:NAD(P)(+)-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0007489 name: NADH dehydrogenase (quinone) activity namespace: molecular_function def: "Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol." [EC:1.6.99.5, GOC:mah, MetaCyc:NADH-DEHYDROGENASE-(QUINONE)-RXN] subset: gosubset_prok synonym: "D-diaphorase activity" EXACT [EC:1.6.99.5] synonym: "DPNH-menadione reductase activity" EXACT [EC:1.6.99.5] synonym: "NADH-quinone oxidoreductase activity" EXACT [EC:1.6.99.5] synonym: "NADH:(quinone-acceptor) oxidoreductase activity" EXACT [EC:1.6.99.5] synonym: "reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase activity" EXACT [EC:1.6.99.5] xref: EC:1.6.99.5 xref: GO:0050136 xref: MetaCyc:NADH-DEHYDROGENASE-(QUINONE)-RXN is_a: CCO:F0000447 ! NADH dehydrogenase activity is_a: CCO:F0003253 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [Term] id: CCO:F0007490 name: NADPH peroxidase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + H2O2 = NADP+ + 2 H2O." [EC:1.11.1.2, MetaCyc:NADPH-PEROXIDASE-RXN] synonym: "NADP peroxidase activity" EXACT [EC:1.11.1.2] synonym: "NADPH:hydrogen-peroxide oxidoreductase activity" EXACT [EC:1.11.1.2] synonym: "nicotinamide adenine dinucleotide phosphate peroxidase activity" EXACT [EC:1.11.1.2] synonym: "TPN peroxidase activity" EXACT [EC:1.11.1.2] synonym: "TPNH peroxidase activity" EXACT [EC:1.11.1.2] synonym: "triphosphopyridine nucleotide peroxidase activity" EXACT [EC:1.11.1.2] xref: EC:1.11.1.2 xref: GO:0050137 xref: MetaCyc:NADPH-PEROXIDASE-RXN is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0007491 name: nicotinate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: nicotinate + H2O + NADP+ = 6-hydroxynicotinate + NADPH." [EC:1.17.1.5, MetaCyc:NICOTINATE-DEHYDROGENASE-RXN] synonym: "nicotinate hydroxylase activity" EXACT [EC:1.17.1.5] synonym: "nicotinate:NADP+ 6-oxidoreductase (hydroxylating)" EXACT [EC:1.17.1.5] synonym: "nicotinic acid hydroxylase activity" EXACT [EC:1.17.1.5] xref: EC:1.17.1.5 xref: GO:0050138 xref: MetaCyc:NICOTINATE-DEHYDROGENASE-RXN is_a: CCO:F0003308 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [Term] id: CCO:F0007492 name: nicotinate glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + nicotinate = UDP + N-glucosylnicotinate." [EC:2.4.1.196, MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN] synonym: "UDP-glucose:nicotinate N-glucosyltransferase activity" EXACT [EC:2.4.1.196] synonym: "UDP-glucose:nicotinic acid-N-glucosyltransferase activity" EXACT [EC:2.4.1.196] synonym: "UDPglucose:nicotinate N-glucosyltransferase activity" EXACT [EC:2.4.1.196] synonym: "uridine diphosphoglucose-nicotinate N-glucosyltransferase activity" EXACT [EC:2.4.1.196] xref: EC:2.4.1.196 xref: GO:0050139 xref: MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007493 name: nitrate reductase (cytochrome) activity namespace: molecular_function def: "Catalysis of the reaction: ferrocytochrome + NO3- (nitrate) = ferricytochrome + NO2- (nitrite)." [EC:1.9.6.1, MetaCyc:NITRATE-REDUCTASE-(CYTOCHROME)-RXN] synonym: "benzyl viologen-nitrate reductase activity" EXACT [EC:1.9.6.1] synonym: "ferrocytochrome:nitrate oxidoreductase activity" EXACT [EC:1.9.6.1] xref: EC:1.9.6.1 xref: GO:0050140 xref: MetaCyc:NITRATE-REDUCTASE-(CYTOCHROME)-RXN is_a: CCO:F0003269 ! oxidoreductase activity, acting on heme group of donors, nitrogenous group as acceptor [Term] id: CCO:F0007494 name: nitroethane oxidase activity namespace: molecular_function def: "Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + NO2(-) (nitrite) + H2O2." [EC:1.7.3.1, MetaCyc:NITROETHANE-OXIDASE-RXN] synonym: "NAO activity" EXACT [EC:1.7.3.1] synonym: "nitroalkane:oxygen oxidoreductase activity" EXACT [EC:1.7.3.1] synonym: "Nitroethane oxidase activity" EXACT [EC:1.7.3.1] synonym: "nitroethane reductase activity" EXACT [EC:1.7.3.1] synonym: "nitroethane:oxygen oxidoreductase activity" EXACT [EC:1.7.3.1] xref: EC:1.7.3.1 xref: GO:0050141 xref: MetaCyc:NITROETHANE-OXIDASE-RXN is_a: CCO:F0003258 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor [Term] id: CCO:F0007495 name: nitrogenase (flavodoxin) activity namespace: molecular_function def: "Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate." [EC:1.19.6.1, MetaCyc:NITROGENASE-(FLAVODOXIN)-RXN] subset: gosubset_prok synonym: "reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing)" EXACT [EC:1.19.6.1] xref: EC:1.19.6.1 xref: GO:0050142 xref: MetaCyc:NITROGENASE-(FLAVODOXIN)-RXN is_a: CCO:F0003315 ! oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor [Term] id: CCO:F0007496 name: nocardicin-A epimerase activity namespace: molecular_function def: "Catalysis of the reaction: isonocardicin A = nocardicin A." [EC:5.1.1.14, MetaCyc:NOCARDICIN-A-EPIMERASE-RXN] synonym: "isonocardicin A epimerase activity" EXACT [EC:5.1.1.14] xref: EC:5.1.1.14 xref: GO:0050143 xref: MetaCyc:NOCARDICIN-A-EPIMERASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0007497 name: nucleoside deoxyribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1." [EC:2.4.2.6, MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN] subset: gosubset_prok synonym: "deoxyribose transferase activity" EXACT [EC:2.4.2.6] synonym: "nucleoside deoxyribosyltransferase I (purine nucleoside:purine deoxyribosyltransferase: strictly specific for transfer between purine bases)" RELATED [EC:2.4.2.6] synonym: "nucleoside deoxyribosyltransferase II [purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyltransferase]" RELATED [EC:2.4.2.6] synonym: "nucleoside trans-N-deoxyribosylase activity" EXACT [EC:2.4.2.6] synonym: "nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase activity" EXACT [EC:2.4.2.6] synonym: "purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase activity" EXACT [EC:2.4.2.6] synonym: "trans-deoxyribosylase activity" EXACT [EC:2.4.2.6] synonym: "trans-N-deoxyribosylase activity" EXACT [EC:2.4.2.6] synonym: "trans-N-glycosidase activity" EXACT [EC:2.4.2.6] xref: EC:2.4.2.6 xref: GO:0050144 xref: MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0007498 name: nucleoside phosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nucleoside phosphate = ADP + nucleoside diphosphate." [EC:2.7.4.4, MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN] synonym: "ATP:nucleoside-phosphate phosphotransferase activity" EXACT [EC:2.7.4.4] synonym: "NMP-kinase activity" EXACT [EC:2.7.4.4] synonym: "nucleoside-phosphate kinase activity" EXACT [] xref: EC:2.7.4.4 xref: GO:0050145 xref: MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0007499 name: nucleoside phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate." [EC:2.7.1.77, MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN] synonym: "nonspecific nucleoside phosphotransferase activity" EXACT [EC:2.7.1.77] synonym: "nucleotide:2'-nucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.77] synonym: "nucleotide:3'-deoxynucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.77] synonym: "nucleotide:nucleoside 5'-phosphotransferase activity" EXACT [EC:2.7.1.77] xref: EC:2.7.1.77 xref: GO:0050146 xref: MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0007500 name: nucleoside ribosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1." [EC:2.4.2.5, MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN] synonym: "nucleoside N-ribosyltransferase activity" EXACT [EC:2.4.2.5] synonym: "nucleoside:purine(pyrimidine) D-ribosyltransferase activity" EXACT [EC:2.4.2.5] xref: EC:2.4.2.5 xref: GO:0050147 xref: MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0007501 name: nucleotide diphosphokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate." [EC:2.7.6.4, MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN] synonym: "ATP nucleotide 3'-pyrophosphokinase activity" EXACT [EC:2.7.6.4] synonym: "ATP:nucleoside-5'-phosphate diphosphotransferase activity" EXACT [EC:2.7.6.4] synonym: "ATP:nucleotide pyrophosphotransferase activity" EXACT [EC:2.7.6.4] synonym: "nucleotide 3'-pyrophosphokinase activity" EXACT [EC:2.7.6.4] synonym: "nucleotide pyrophosphokinase activity" EXACT [] xref: EC:2.7.6.4 xref: GO:0050148 xref: MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN is_a: CCO:F0003350 ! diphosphotransferase activity [Term] id: CCO:F0007502 name: o-aminophenol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O." [EC:1.10.3.4, MetaCyc:O-AMINOPHENOL-OXIDASE-RXN] synonym: "2-aminophenol:O2 oxidoreductase activity" EXACT [EC:1.10.3.4] synonym: "2-aminophenol:oxygen oxidoreductase activity" EXACT [EC:1.10.3.4] synonym: "GriF" RELATED [EC:1.10.3.4] synonym: "isophenoxazine synthase activity" EXACT [EC:1.10.3.4] synonym: "o-aminophenol:O2 oxidoreductase activity" EXACT [EC:1.10.3.4] xref: EC:1.10.3.4 xref: GO:0050149 xref: MetaCyc:O-AMINOPHENOL-OXIDASE-RXN is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0007503 name: o-pyrocatechuate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxybenzoate = catechol + CO2." [EC:4.1.1.46, MetaCyc:O-PYROCATECHUATE-DECARBOXYLASE-RXN] synonym: "2,3-DHBA decarboxylase activity" EXACT [EC:4.1.1.46] synonym: "2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)" EXACT [EC:4.1.1.46] synonym: "2,3-dihydroxybenzoate carboxy-lyase activity" EXACT [EC:4.1.1.46] synonym: "2,3-dihydroxybenzoic acid decarboxylase activity" EXACT [EC:4.1.1.46] xref: EC:4.1.1.46 xref: GO:0050150 xref: MetaCyc:O-PYROCATECHUATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007504 name: oleate hydratase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-10-hydroxystearate = oleate + H2O." [EC:4.2.1.53, MetaCyc:OLEATE-HYDRATASE-RXN] synonym: "(R)-10-hydroxystearate 10-hydro-lyase (oleate-forming)" EXACT [EC:4.2.1.53] synonym: "(R)-10-hydroxystearate 10-hydro-lyase activity" EXACT [EC:4.2.1.53] xref: EC:4.2.1.53 xref: GO:0050151 xref: MetaCyc:OLEATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007505 name: omega-amidase activity namespace: molecular_function def: "Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3." [EC:3.5.1.3, MetaCyc:OMEGA-AMIDASE-RXN] synonym: "alpha-keto acid-omega-amidase activity" EXACT [EC:3.5.1.3] synonym: "omega-amidodicarboxylate amidohydrolase activity" EXACT [EC:3.5.1.3] synonym: "w-amidase activity" EXACT [] xref: EC:3.5.1.3 xref: GO:0050152 xref: MetaCyc:OMEGA-AMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007506 name: omega-hydroxydecanoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 10-hydroxydecanoate + NAD+ = 10-oxodecanoate + NADH." [EC:1.1.1.66, MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN] synonym: "10-hydroxydecanoate:NAD+ 10-oxidoreductase activity" EXACT [EC:1.1.1.66] synonym: "w-hydroxydecanoate dehydrogenase activity" EXACT [] xref: EC:1.1.1.66 xref: GO:0050153 xref: MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007507 name: opheline kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = ADP + N'-phosphoguanidinoethyl methylphosphate." [EC:2.7.3.7, MetaCyc:OPHELINE-KINASE-RXN] synonym: "ATP:guanidinoethyl-methyl-phosphate phosphotransferase activity" EXACT [EC:2.7.3.7] xref: EC:2.7.3.7 xref: GO:0050154 xref: MetaCyc:OPHELINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0007508 name: ornithine(lysine) transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate." [EC:2.6.1.68, MetaCyc:ORNITHINE(LYSINE)-AMINOTRANSFERASE-RXN] synonym: "L-ornithine(L-lysine):2-oxoglutarate-aminotransferase activity" EXACT [EC:2.6.1.68] synonym: "L-ornithine:2-oxoglutarate-aminotransferase activity" EXACT [EC:2.6.1.68] synonym: "lysine/ornithine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.68] synonym: "ornithine(lysine) aminotransferase activity" EXACT [] xref: EC:2.6.1.68 xref: GO:0050155 xref: MetaCyc:ORNITHINE(LYSINE)-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007509 name: ornithine N-benzoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 benzoyl-CoA + L-ornithine = 2 CoA + N2,N5-dibenzoyl-L-ornithine." [EC:2.3.1.127, MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN] synonym: "benzoyl-CoA:L-ornithine N-benzoyltransferase activity" EXACT [EC:2.3.1.127] synonym: "ornithine N-acyltransferase activity" EXACT [EC:2.3.1.127] xref: EC:2.3.1.127 xref: GO:0050156 xref: MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007510 name: ornithine racemase activity namespace: molecular_function def: "Catalysis of the reaction: L-ornithine = D-ornithine." [EC:5.1.1.12, MetaCyc:ORNITHINE-RACEMASE-RXN] subset: gosubset_prok xref: EC:5.1.1.12 xref: GO:0050157 xref: MetaCyc:ORNITHINE-RACEMASE-RXN is_a: CCO:F0003418 ! racemase and epimerase activity, acting on amino acids and derivatives [Term] id: CCO:F0007511 name: orotate reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: (S)-dihydroorotate + NADP+ = orotate + NADPH." [EC:1.3.1.15, MetaCyc:OROTATE-REDUCTASE-(NADPH)-RXN] synonym: "(S)-dihydroorotate:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.15] synonym: "dihydro-orotic dehydrogenase activity" EXACT [EC:1.3.1.15] synonym: "L-5,6-dihydro-orotate:NAD oxidoreductase activity" EXACT [EC:1.3.1.15] synonym: "orotate reductase activity" EXACT [EC:1.3.1.15] xref: EC:1.3.1.15 xref: GO:0050158 xref: MetaCyc:OROTATE-REDUCTASE-(NADPH)-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007512 name: orsellinate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dihydroxy-6-methylbenzoate = orcinol + CO2." [EC:4.1.1.58, MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN] synonym: "orsellinate carboxy-lyase (orcinol-forming)" EXACT [EC:4.1.1.58] synonym: "orsellinate carboxy-lyase activity" EXACT [EC:4.1.1.58] xref: EC:4.1.1.58 xref: GO:0050159 xref: MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007513 name: orsellinate-depside hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: orsellinate depside + H2O = 2 orsellinate." [EC:3.1.1.40, MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN] synonym: "lecanorate hydrolase activity" EXACT [EC:3.1.1.40] xref: EC:3.1.1.40 xref: GO:0050160 xref: MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007514 name: oxalate CoA-transferase activity namespace: molecular_function def: "Catalysis of the reaction: succinyl-CoA + oxalate = succinate + oxalyl-CoA." [EC:2.8.3.2, MetaCyc:OXALATE-COA-TRANSFERASE-RXN] synonym: "oxalate coenzyme A-transferase activity" EXACT [EC:2.8.3.2] synonym: "succinyl-beta-ketoacyl-CoA transferase activity" EXACT [EC:2.8.3.2] synonym: "succinyl-CoA:oxalate CoA-transferase activity" EXACT [EC:2.8.3.2] xref: EC:2.8.3.2 xref: GO:0050161 xref: MetaCyc:OXALATE-COA-TRANSFERASE-RXN is_a: CCO:F0001877 ! CoA-transferase activity [Term] id: CCO:F0007515 name: oxalate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: oxalate + O2 = 2 CO2 + H2O2." [EC:1.2.3.4, MetaCyc:OXALATE-OXIDASE-RXN] synonym: "aero-oxalo dehydrogenase activity" EXACT [EC:1.2.3.4] synonym: "oxalate:oxygen oxidoreductase activity" EXACT [EC:1.2.3.4] synonym: "oxalic acid oxidase activity" EXACT [EC:1.2.3.4] xref: EC:1.2.3.4 xref: GO:0050162 xref: MetaCyc:OXALATE-OXIDASE-RXN is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0007516 name: oxaloacetate tautomerase activity namespace: molecular_function def: "Catalysis of the reaction: keto-oxaloacetate = enol-oxaloacetate." [EC:5.3.2.2, MetaCyc:OXALOACETATE-TAUTOMERASE-RXN] synonym: "oxalacetic keto-enol isomerase activity" EXACT [EC:5.3.2.2] synonym: "oxaloacetate keto-enol tautomerase activity" EXACT [EC:5.3.2.2] synonym: "oxaloacetate keto-enol-isomerase activity" EXACT [EC:5.3.2.2] xref: EC:5.3.2.2 xref: GO:0050163 xref: MetaCyc:OXALOACETATE-TAUTOMERASE-RXN is_a: CCO:F0003424 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups [Term] id: CCO:F0007517 name: oxoglutarate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + CoA + NADP+ = succinyl-CoA + CO2 + NADPH." [EC:1.2.1.52, MetaCyc:OXOGLUTARATE-DEHYDROGENASE-(NADP+)-RXN] synonym: "2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating)" EXACT [EC:1.2.1.52] xref: EC:1.2.1.52 xref: GO:0050164 xref: MetaCyc:OXOGLUTARATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0008471 ! oxoglutarate dehydrogenase [NAD(P)+] activity [Term] id: CCO:F0007518 name: pantetheine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate." [EC:2.7.1.34, MetaCyc:PANTETHEINE-KINASE-RXN] synonym: "ATP:pantetheine 4'-phosphotransferase activity" EXACT [EC:2.7.1.34] synonym: "pantetheine kinase (phosphorylating)" EXACT [EC:2.7.1.34] xref: EC:2.7.1.34 xref: GO:0050165 xref: MetaCyc:PANTETHEINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007519 name: pantoate 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-pantoate + NAD+ = (R)-4-dehydropantoate + NADH." [EC:1.1.1.106, MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN] synonym: "(R)-pantoate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.106] synonym: "D-pantoate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.106] synonym: "panthothenase activity" EXACT [EC:1.1.1.106] synonym: "pantoate dehydrogenase activity" EXACT [EC:1.1.1.106] xref: EC:1.1.1.106 xref: GO:0050166 xref: MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007520 name: pantothenoylcysteine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine = pantetheine + CO2." [EC:4.1.1.30, MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN] synonym: "N-((R)-pantothenoyl)-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.30] synonym: "N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming)" EXACT [EC:4.1.1.30] synonym: "N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase activity" EXACT [EC:4.1.1.30] synonym: "pantothenylcysteine decarboxylase activity" EXACT [EC:4.1.1.30] xref: EC:4.1.1.30 xref: GO:0050167 xref: MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007521 name: pentanamidase activity namespace: molecular_function def: "Catalysis of the reaction: pentanamide + H2O = pentanoate + NH3." [EC:3.5.1.50, MetaCyc:PENTANAMIDASE-RXN] synonym: "pentanamide amidohydrolase activity" EXACT [EC:3.5.1.50] synonym: "valeramidase activity" EXACT [EC:3.5.1.50] xref: EC:3.5.1.50 xref: GO:0050168 xref: MetaCyc:PENTANAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007522 name: peptide-tryptophan 2,3-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine." [EC:1.13.11.26, MetaCyc:PEPTIDE-TRYPTOPHAN-2] synonym: "peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.26] synonym: "peptidyltryptophan 2,3-dioxygenase activity" EXACT [EC:1.13.11.26] synonym: "pyrrolooxygenase activity" EXACT [EC:1.13.11.26] synonym: "tryptophan pyrrolooxygenase activity" EXACT [EC:1.13.11.26] xref: EC:1.13.11.26 xref: GO:0050169 xref: MetaCyc:PEPTIDE-TRYPTOPHAN-2 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007523 name: peptidyl-glutaminase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3." [EC:3.5.1.43, MetaCyc:PEPTIDYL-GLUTAMINASE-RXN] synonym: "peptideglutaminase activity" EXACT [EC:3.5.1.43] synonym: "peptidoglutaminase activity" EXACT [EC:3.5.1.43] synonym: "peptidoglutaminase I activity" NARROW [EC:3.5.1.43] synonym: "peptidyl-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.43] xref: EC:3.5.1.43 xref: GO:0050170 xref: MetaCyc:PEPTIDYL-GLUTAMINASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007524 name: phenol beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside." [EC:2.4.1.35, MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "phenol b-glucosyltransferase activity" EXACT [] synonym: "phenol-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.35] synonym: "UDP glucosyltransferase activity" EXACT [EC:2.4.1.35] synonym: "UDP-glucose glucosyltransferase activity" EXACT [EC:2.4.1.35] synonym: "UDP-glucose:phenol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.35] synonym: "UDPglucose:phenol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.35] synonym: "UDPglucosyltransferase activity" EXACT [EC:2.4.1.35] synonym: "uridine diphosphoglucosyltransferase activity" EXACT [EC:2.4.1.35] xref: EC:2.4.1.35 xref: GO:0050171 xref: MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007525 name: phenylalanine 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O." [EC:1.13.12.9, MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN] subset: gosubset_prok synonym: "L-phenylalanine oxidase (deaminating and decarboxylating)" EXACT [EC:1.13.12.9] synonym: "l-phenylalanine oxidase (deaminating and decarboxylating) activity" EXACT [EC:1.13.12.9] synonym: "L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.9] synonym: "phenylalanine (deaminating, decarboxylating) oxidase activity" EXACT [EC:1.13.12.9] synonym: "phenylalanine (deaminating, decarboxylating)oxidase activity" EXACT [EC:1.13.12.9] xref: EC:1.13.12.9 xref: GO:0050172 xref: MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) [Term] id: CCO:F0007526 name: phenylalanine adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-phenylalanine = diphosphate + N-adenylyl-L-phenylalanine." [EC:2.7.7.54, MetaCyc:PHENYLALANINE-ADENYLYLTRANSFERASE-RXN] synonym: "ATP:L-phenylalanine adenylyltransferase activity" EXACT [EC:2.7.7.54] synonym: "ATP:phenylalanine adenylyltransferase activity" EXACT [] synonym: "L-phenylalanine adenylyltransferase activity" EXACT [EC:2.7.7.54] xref: EC:2.7.7.54 xref: GO:0050173 xref: MetaCyc:PHENYLALANINE-ADENYLYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0007527 name: phenylalanine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2." [EC:4.1.1.53, MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN] synonym: "aromatic L-amino acid decarboxylase activity" EXACT [EC:4.1.1.53] synonym: "L-phenylalanine carboxy-lyase (phenylethylamine-forming)" EXACT [EC:4.1.1.53] synonym: "L-phenylalanine carboxy-lyase activity" EXACT [EC:4.1.1.53] synonym: "L-phenylalanine decarboxylase activity" EXACT [EC:4.1.1.53] xref: EC:4.1.1.53 xref: GO:0050174 xref: MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007528 name: phenylalanine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH." [EC:1.4.1.20, MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "L-phenylalanine dehydrogenase activity" EXACT [EC:1.4.1.20] synonym: "L-phenylalanine:NAD+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.20] synonym: "PHD" RELATED [EC:1.4.1.20] synonym: "PheDH activity" EXACT [EC:1.4.1.20] xref: EC:1.4.1.20 xref: GO:0050175 xref: MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007529 name: phenylalanine N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + L-phenylalanine = CoA + N-acetyl-L-phenylalanine." [EC:2.3.1.53, MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA-L-phenylalanine alpha-N-acetyltransferase activity" EXACT [EC:2.3.1.53] synonym: "acetyl-CoA:L-phenylalanine N-acetyltransferase activity" EXACT [EC:2.3.1.53] xref: EC:2.3.1.53 xref: GO:0050176 xref: MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0007530 name: phenylpyruvate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2." [EC:4.1.1.43, MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN] synonym: "phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming)" EXACT [EC:4.1.1.43] synonym: "phenylpyruvate carboxy-lyase activity" EXACT [EC:4.1.1.43] xref: EC:4.1.1.43 xref: GO:0050177 xref: MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007531 name: phenylpyruvate tautomerase activity namespace: molecular_function def: "Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate." [EC:5.3.2.1, MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN] subset: gosubset_prok synonym: "phenylpyruvate keto--enol tautomerase activity" EXACT [EC:5.3.2.1] synonym: "phenylpyruvate keto-enol-isomerase activity" EXACT [EC:5.3.2.1] synonym: "phenylpyruvic keto--enol isomerase activity" EXACT [EC:5.3.2.1] xref: EC:5.3.2.1 xref: GO:0050178 xref: MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN is_a: CCO:F0003424 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups [Term] id: CCO:F0007532 name: phenylserine aldolase activity namespace: molecular_function def: "Catalysis of the reaction: L-threo-3-phenylserine = glycine + benzaldehyde." [EC:4.1.2.26, MetaCyc:PHENYLSERINE-ALDOLASE-RXN] synonym: "L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming)" EXACT [EC:4.1.2.26] synonym: "L-threo-3-phenylserine benzaldehyde-lyase activity" EXACT [EC:4.1.2.26] xref: EC:4.1.2.26 xref: GO:0050179 xref: MetaCyc:PHENYLSERINE-ALDOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007533 name: phloretin hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: phloretin + H2O = phloretate + phloroglucinol." [EC:3.7.1.4, MetaCyc:PHLORETIN-HYDROLASE-RXN] synonym: "2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase activity" EXACT [EC:3.7.1.4] synonym: "lactase-phlorizin hydrolase" BROAD [EC:3.7.1.4] xref: EC:3.7.1.4 xref: GO:0050180 xref: MetaCyc:PHLORETIN-HYDROLASE-RXN is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0007534 name: phorbol-diester hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: phorbol 12,13-dibutanoate + H2O = phorbol 13-butanoate + butanoate." [EC:3.1.1.51, MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN] synonym: "12,13-diacylphorbate 12-acylhydrolase activity" EXACT [EC:3.1.1.51] synonym: "diacylphorbate 12-hydrolase activity" EXACT [EC:3.1.1.51] synonym: "PDEH" RELATED [EC:3.1.1.51] synonym: "phorbol-12,13-diester 12-ester hydrolase activity" EXACT [EC:3.1.1.51] xref: EC:3.1.1.51 xref: GO:0050181 xref: MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007535 name: phosphate butyryltransferase activity namespace: molecular_function def: "Catalysis of the reaction: butanoyl-CoA + phosphate = CoA + butanoylphosphate." [EC:2.3.1.19, MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN] subset: gosubset_prok synonym: "butanoyl-CoA:phosphate butanoyltransferase activity" EXACT [EC:2.3.1.19] synonym: "phosphotransbutyrylase activity" EXACT [EC:2.3.1.19] xref: EC:2.3.1.19 xref: GO:0050182 xref: MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007536 name: phosphatidylcholine 12-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NADH + O2 = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + NAD+ + H2O." [EC:1.14.13.26, MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN] synonym: "1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)" EXACT [EC:1.14.13.26] synonym: "oleate D12-hydroxylase activity" EXACT [] synonym: "oleate Delta(12)-hydroxylase activity" EXACT [EC:1.14.13.26] synonym: "oleate delta12-hydroxylase activity" EXACT [EC:1.14.13.26] synonym: "oleate delta12-monooxygenase activity" EXACT [EC:1.14.13.26] synonym: "ricinoleic acid synthase activity" EXACT [EC:1.14.13.26] xref: EC:1.14.13.26 xref: GO:0050183 xref: MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007537 name: phosphatidylcholine desaturase activity namespace: molecular_function def: "Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD+ = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + NADH." [EC:1.3.1.35, MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN] synonym: "1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase activity" EXACT [EC:1.3.1.35] synonym: "linoleate synthase activity" EXACT [EC:1.3.1.35] synonym: "oleate desaturase activity" EXACT [EC:1.3.1.35] synonym: "oleoyl-CoA desaturase activity" EXACT [EC:1.3.1.35] synonym: "oleoylphosphatidylcholine desaturase activity" EXACT [EC:1.3.1.35] xref: EC:1.3.1.35 xref: GO:0050184 xref: MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007538 name: phosphatidylinositol deacylase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phosphatidyl-D-myo-inositol + H2O = 1-acylglycerophosphoinositol + a carboxylate." [EC:3.1.1.52, MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN] synonym: "1-phosphatidyl-D-myo-inositol 2-acylhydrolase activity" EXACT [EC:3.1.1.52] synonym: "phosphatidylinositol phospholipase A2 activity" EXACT [EC:3.1.1.52] xref: EC:3.1.1.52 xref: GO:0050185 xref: MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007539 name: phosphoadenylylsulfatase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + SO4(2-) (sulfate)." [EC:3.6.2.2, MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN] synonym: "3'-phosphoadenylylsulfate sulfohydrolase activity" EXACT [EC:3.6.2.2] synonym: "3-phosphoadenosine 5-phosphosulfate sulfatase activity" EXACT [EC:3.6.2.2] synonym: "3-phosphoadenylyl sulfatase activity" EXACT [EC:3.6.2.2] synonym: "PAPS sulfatase activity" EXACT [EC:3.6.2.2] synonym: "phosphoadenylylsulphatase activity" EXACT [] xref: EC:3.6.2.2 xref: GO:0050186 xref: MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN is_a: CCO:F0003387 ! hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides [Term] id: CCO:F0007540 name: phosphoamidase activity namespace: molecular_function def: "Catalysis of the reaction: N-phosphocreatine + H2O = creatine + phosphate." [EC:3.9.1.1, MetaCyc:PHOSPHOAMIDASE-RXN] synonym: "creatine phosphatase activity" EXACT [EC:3.9.1.1] synonym: "phosphamide hydrolase activity" EXACT [EC:3.9.1.1] xref: EC:3.9.1.1 xref: GO:0050187 xref: MetaCyc:PHOSPHOAMIDASE-RXN is_a: CCO:F0003392 ! hydrolase activity, acting on acid phosphorus-nitrogen bonds [Term] id: CCO:F0007541 name: phosphoenolpyruvate mutase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate." [EC:5.4.2.9, MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN] subset: gosubset_prok synonym: "PEP mutase activity" EXACT [EC:5.4.2.9] synonym: "PEP phosphomutase activity" EXACT [EC:5.4.2.9] synonym: "PEPPM" RELATED [EC:5.4.2.9] synonym: "phosphoenolpyruvate 2,3-phosphonomutase activity" EXACT [EC:5.4.2.9] synonym: "phosphoenolpyruvate phosphomutase activity" EXACT [EC:5.4.2.9] synonym: "phosphoenolpyruvate-phosphonopyruvate phosphomutase activity" EXACT [EC:5.4.2.9] xref: EC:5.4.2.9 xref: GO:0050188 xref: MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN is_a: CCO:F0003429 ! intramolecular transferase activity, phosphotransferases [Term] id: CCO:F0007542 name: phosphoenolpyruvate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate + H2O = pyruvate + phosphate." [EC:3.1.3.60, MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN] synonym: "PEP phosphatase activity" EXACT [EC:3.1.3.60] synonym: "phosphoenolpyruvate phosphohydrolase activity" EXACT [EC:3.1.3.60] xref: EC:3.1.3.60 xref: GO:0050189 xref: MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007543 name: phosphoglucokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-glucose 1-phosphate = ADP + D-glucose 1,6-bisphosphate." [EC:2.7.1.10, MetaCyc:PHOSPHOGLUCOKINASE-RXN] synonym: "ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.10] synonym: "ATP:D-glucose-1-phosphate 6-phosphotransferase activity" EXACT [EC:2.7.1.10] synonym: "glucose-phosphate kinase activity" EXACT [EC:2.7.1.10] synonym: "phosphoglucokinase (phosphorylating)" EXACT [EC:2.7.1.10] xref: EC:2.7.1.10 xref: GO:0050190 xref: MetaCyc:PHOSPHOGLUCOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007544 name: phosphoglycerate kinase (GTP) activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 3-phospho-D-glycerate = GDP + 3-phospho-D-glyceroyl phosphate." [EC:2.7.2.10, MetaCyc:PHOSPHOGLYCERATE-KINASE-(GTP)-RXN] synonym: "GTP:3-phospho-D-glycerate 1-phosphotransferase activity" EXACT [EC:2.7.2.10] xref: EC:2.7.2.10 xref: GO:0050191 xref: MetaCyc:PHOSPHOGLYCERATE-KINASE-(GTP)-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003346 ! phosphotransferase activity, carboxyl group as acceptor [Term] id: CCO:F0007545 name: phosphoglycerate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-glycerate 2-phosphate + H2O = D-glycerate + phosphate." [EC:3.1.3.20, MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN] synonym: "D-2-phosphoglycerate phosphatase activity" EXACT [EC:3.1.3.20] synonym: "D-glycerate-2-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.20] synonym: "glycerophosphate phosphatase activity" EXACT [EC:3.1.3.20] xref: EC:3.1.3.20 xref: GO:0050192 xref: MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007546 name: phosphoketolase activity namespace: molecular_function def: "Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O." [EC:4.1.2.9, MetaCyc:PHOSPHOKETOLASE-RXN] subset: gosubset_prok synonym: "D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)" EXACT [EC:4.1.2.9] synonym: "D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating) activity" EXACT [EC:4.1.2.9] synonym: "xylulose-5-phosphate phosphoketolase activity" EXACT [EC:4.1.2.9] xref: EC:4.1.2.9 xref: GO:0050193 xref: MetaCyc:PHOSPHOKETOLASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007547 name: phosphonoacetaldehyde hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: phosphonoacetaldehyde + H2O = acetaldehyde + phosphate." [EC:3.11.1.1, MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN] subset: gosubset_prok synonym: "2-oxoethylphosphonate phosphonohydrolase activity" EXACT [EC:3.11.1.1] synonym: "2-phosphonoacetylaldehyde phosphonohydrolase activity" EXACT [EC:3.11.1.1] synonym: "phosphonatase activity" EXACT [EC:3.11.1.1] synonym: "phosphonoacetylaldehyde phosphonohydrolase activity" EXACT [EC:3.11.1.1] xref: EC:3.11.1.1 xref: GO:0050194 xref: MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN is_a: CCO:F0003394 ! hydrolase activity, acting on acid carbon-phosphorus bonds [Term] id: CCO:F0007548 name: phosphoribokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-ribose 5-phosphate = ADP + D-ribose 1,5-bisphosphate." [EC:2.7.1.18, MetaCyc:PHOSPHORIBOKINASE-RXN] synonym: "ATP:D-ribose-5-phosphate 1-phosphotransferase activity" EXACT [EC:2.7.1.18] synonym: "phosphoribokinase (phosphorylating)" EXACT [EC:2.7.1.18] xref: EC:2.7.1.18 xref: GO:0050195 xref: MetaCyc:PHOSPHORIBOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007550 name: phytanate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + phytanate + CoA = AMP + diphosphate + phytanoyl-CoA." [EC:6.2.1.24, MetaCyc:PHYTANATE--COA-LIGASE-RXN] subset: gosubset_prok synonym: "phytanate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.24] synonym: "phytanoyl-CoA ligase activity" EXACT [EC:6.2.1.24] xref: EC:6.2.1.24 xref: GO:0050197 xref: MetaCyc:PHYTANATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007551 name: pinosylvin synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3 malonyl-CoA + cinnamoyl-CoA = 4 CoA + pinosylvin + 4 CO2." [EC:2.3.1.146, MetaCyc:PINOSYLVIN-SYNTHASE-RXN] synonym: "malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)" EXACT [EC:2.3.1.146] synonym: "pine stilbene synthase activity" EXACT [EC:2.3.1.146] synonym: "stilbene synthase activity" BROAD [EC:2.3.1.146] xref: EC:2.3.1.146 xref: GO:0050198 xref: MetaCyc:PINOSYLVIN-SYNTHASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007552 name: piperidine N-piperoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = CoA + N-[(E,E)-piperoyl]-piperidine." [EC:2.3.1.145, MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN] synonym: "(E,E)-piperoyl-CoA:piperidine N-piperoyltransferase activity" EXACT [EC:2.3.1.145] synonym: "piperidine piperoyltransferase activity" EXACT [EC:2.3.1.145] synonym: "piperoyl-CoA:piperidine N-piperoyltransferase activity" EXACT [EC:2.3.1.145] xref: EC:2.3.1.145 xref: GO:0050199 xref: MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007553 name: plasmalogen synthase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine." [EC:2.3.1.25, MetaCyc:PLASMALOGEN-SYNTHASE-RXN] synonym: "1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase activity" EXACT [EC:2.3.1.25] synonym: "acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase activity" EXACT [EC:2.3.1.25] synonym: "lysoplasmenylcholine acyltransferase activity" EXACT [EC:2.3.1.25] synonym: "O-1-alkenylglycero-3-phosphorylcholine acyltransferase activity" EXACT [EC:2.3.1.25] xref: EC:2.3.1.25 xref: GO:0050200 xref: MetaCyc:PLASMALOGEN-SYNTHASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007554 name: fucokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 6-deoxy-L-galactose = ADP + 6-deoxy-L-galactose 1-phosphate." [EC:2.7.1.52, MetaCyc:FUCOKINASE-RXN] synonym: "ATP:6-deoxy-L-galactose 1-phosphotransferase activity" EXACT [EC:2.7.1.52] synonym: "ATP:beta-L-fucose 1-phosphotransferase activity" EXACT [EC:2.7.1.52] synonym: "fucokinase (phosphorylating) activity" EXACT [EC:2.7.1.52] synonym: "fucose kinase activity" EXACT [EC:2.7.1.52] synonym: "L-fucokinase activity" EXACT [EC:2.7.1.52] synonym: "L-fucose kinase activity" EXACT [EC:2.7.1.52] xref: EC:2.7.1.52 xref: GO:0050201 xref: MetaCyc:FUCOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007555 name: octopamine dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH3." [EC:4.2.1.87, MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN] synonym: "octopamine hydro-lyase (deaminating)" EXACT [EC:4.2.1.87] synonym: "octopamine hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]" RELATED [EC:4.2.1.87] synonym: "octopamine hydrolyase activity" EXACT [EC:4.2.1.87] xref: EC:4.2.1.87 xref: GO:0050202 xref: MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007556 name: oxalate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + oxalate + CoA = AMP + diphosphate + oxalyl-CoA." [EC:6.2.1.8, MetaCyc:OXALATE--COA-LIGASE-RXN] synonym: "oxalate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.8] synonym: "oxalyl coenzyme A synthetase activity" EXACT [EC:6.2.1.8] synonym: "oxalyl-CoA synthetase activity" EXACT [EC:6.2.1.8] xref: EC:6.2.1.8 xref: GO:0050203 xref: MetaCyc:OXALATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007557 name: oxalomalate lyase activity namespace: molecular_function def: "Catalysis of the reaction: 3-oxalomalate = oxaloacetate + glyoxylate." [EC:4.1.3.13, MetaCyc:OXALOMALATE-LYASE-RXN] synonym: "3-oxalomalate glyoxylate-lyase (oxaloacetate-forming)" EXACT [EC:4.1.3.13] synonym: "3-oxalomalate glyoxylate-lyase activity" EXACT [EC:4.1.3.13] xref: EC:4.1.3.13 xref: GO:0050204 xref: MetaCyc:OXALOMALATE-LYASE-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0007558 name: oxamate carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: carbamoyl phosphate + oxamate = phosphate + oxalureate." [EC:2.1.3.5, MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN] synonym: "carbamoyl-phosphate:oxamate carbamoyltransferase activity" EXACT [EC:2.1.3.5] synonym: "oxamic transcarbamylase activity" EXACT [EC:2.1.3.5] xref: EC:2.1.3.5 xref: GO:0050205 xref: MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0007559 name: oximinotransferase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate oxime + acetone = pyruvate + acetone oxime." [EC:2.6.3.1, MetaCyc:OXIMINOTRANSFERASE-RXN] synonym: "oximase activity" EXACT [EC:2.6.3.1] synonym: "pyruvate-acetone oximinotransferase activity" EXACT [EC:2.6.3.1] synonym: "pyruvate-oxime:acetone oximinotransferase activity" EXACT [EC:2.6.3.1] synonym: "transoximase activity" EXACT [EC:2.6.3.1] synonym: "transoximinase activity" EXACT [EC:2.6.3.1] xref: EC:2.6.3.1 xref: GO:0050206 xref: MetaCyc:OXIMINOTRANSFERASE-RXN is_a: CCO:F0003343 ! oximinotransaminase activity [Term] id: CCO:F0007560 name: plasmanylethanolamine desaturase activity namespace: molecular_function def: "Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O." [EC:1.14.99.19, MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN] synonym: "1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity" EXACT [EC:1.14.99.19] synonym: "1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity" EXACT [EC:1.14.99.19] synonym: "alkylacylglycero-phosphorylethanolamine dehydrogenase activity" EXACT [EC:1.14.99.19] synonym: "alkylacylglycerophosphoethanolamine desaturase activity" EXACT [EC:1.14.99.19] synonym: "dehydrogenase, alkyl-acylglycerophosphorylethanolamine" EXACT [EC:1.14.99.19] synonym: "O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.19] synonym: "plasmenylethanolamine desaturase activity" EXACT [] xref: EC:1.14.99.19 xref: GO:0050207 xref: MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007561 name: polysialic-acid O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9." [EC:2.3.1.136, MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:polysialic-acid O-acetyltransferase activity" EXACT [EC:2.3.1.136] synonym: "lecithin retinol acyl transferase activity" EXACT [EC:2.3.1.136] synonym: "lecithin:retinol acyltransferase activity" EXACT [EC:2.3.1.136] synonym: "LRAT" RELATED [EC:2.3.1.136] synonym: "retinyl ester synthase activity" EXACT [EC:2.3.1.136] xref: EC:2.3.1.136 xref: GO:0050208 xref: MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0007562 name: polyvinyl-alcohol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2." [EC:1.1.3.30, MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN] synonym: "dehydrogenase, polyvinyl alcohol" EXACT [EC:1.1.3.30] synonym: "polyvinyl-alcohol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.30] synonym: "PVA oxidase activity" EXACT [EC:1.1.3.30] xref: EC:1.1.3.30 xref: GO:0050209 xref: MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007563 name: prenyl-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate." [EC:3.1.7.1, MetaCyc:PRENYL-PYROPHOSPHATASE-RXN] synonym: "prenol pyrophosphatase activity" EXACT [EC:3.1.7.1] synonym: "prenyl-diphosphate diphosphohydrolase activity" EXACT [EC:3.1.7.1] synonym: "prenyl-pyrophosphatase activity" EXACT [] synonym: "prenylphosphatase activity" EXACT [EC:3.1.7.1] xref: EC:3.1.7.1 xref: GO:0050210 xref: MetaCyc:PRENYL-PYROPHOSPHATASE-RXN is_a: CCO:F0003364 ! diphosphoric monoester hydrolase activity [Term] id: CCO:F0007564 name: procollagen galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine." [EC:2.4.1.50, MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN] synonym: "collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] synonym: "collagen hydroxylysyl galactosyltransferase activity" EXACT [EC:2.4.1.50] synonym: "hydroxylysine galactosyltransferase activity" EXACT [EC:2.4.1.50] synonym: "UDP galactose-collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] synonym: "UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity" EXACT [EC:2.4.1.50] synonym: "UDPgalactose:5-hydroxylysine-collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] synonym: "UDPgalactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity" EXACT [EC:2.4.1.50] synonym: "uridine diphosphogalactose-collagen galactosyltransferase activity" EXACT [EC:2.4.1.50] xref: EC:2.4.1.50 xref: GO:0050211 xref: MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0007565 name: progesterone 11-alpha-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: progesterone + donor-H2 + O2 = 11-alpha-hydroxyprogesterone + acceptor + H2O." [EC:1.14.99.14, MetaCyc:PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXN] synonym: "progesterone 11-alpha-hydroxylase activity" EXACT [EC:1.14.99.14] synonym: "progesterone 11a-monooxygenase activity" EXACT [] synonym: "progesterone 11alpha-hydroxylase activity" EXACT [EC:1.14.99.14] synonym: "progesterone 11alpha-monooxygenase activity" EXACT [EC:1.14.99.14] synonym: "progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)" EXACT [EC:1.14.99.14] xref: EC:1.14.99.14 xref: GO:0050212 xref: MetaCyc:PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007566 name: progesterone 5-alpha-reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH." [EC:1.3.1.30, MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN] synonym: "5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase activity" EXACT [EC:1.3.1.30] synonym: "delta4-steroid 5alpha-reductase (progesterone)" EXACT [EC:1.3.1.30] synonym: "progesterone 5a-reductase activity" EXACT [] synonym: "progesterone 5alpha-reductase activity" EXACT [EC:1.3.1.30] synonym: "steroid 5-alpha-reductase activity" BROAD [EC:1.3.1.30] xref: EC:1.3.1.30 xref: GO:0050213 xref: MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007567 name: progesterone monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: progesterone + donor-H2 + O2 = testosterone acetate + acceptor + H2O." [EC:1.14.99.4, MetaCyc:PROGESTERONE-MONOOXYGENASE-RXN] synonym: "progesterone hydroxylase activity" EXACT [EC:1.14.99.4] synonym: "progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)" EXACT [EC:1.14.99.4] xref: EC:1.14.99.4 xref: GO:0050214 xref: MetaCyc:PROGESTERONE-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007568 name: propanediol dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: propane-1,2-diol = propanal + H2O." [EC:4.2.1.28, MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN] subset: gosubset_prok synonym: "1,2-propanediol dehydratase activity" EXACT [EC:4.2.1.28] synonym: "adenosylcobalamin-dependent diol dehydratase activity" EXACT [EC:4.2.1.28] synonym: "coenzyme B12-dependent diol dehydrase activity" EXACT [EC:4.2.1.28] synonym: "diol dehydrase activity" EXACT [EC:4.2.1.28] synonym: "diol dehydratase activity" EXACT [EC:4.2.1.28] synonym: "dioldehydratase activity" EXACT [EC:4.2.1.28] synonym: "DL-1,2-propanediol hydro-lyase activity" EXACT [EC:4.2.1.28] synonym: "meso-2,3-butanediol dehydrase activity" EXACT [EC:4.2.1.28] synonym: "propane-1,2-diol hydro-lyase (propanal-forming)" EXACT [EC:4.2.1.28] synonym: "propane-1,2-diol hydro-lyase activity" EXACT [EC:4.2.1.28] synonym: "propanediol dehydrase activity" EXACT [EC:4.2.1.28] xref: EC:4.2.1.28 xref: GO:0050215 xref: MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007569 name: propanediol-phosphate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: propane-1,2-diol 1-phosphate + NAD+ = hydroxyacetone phosphate + NADH." [EC:1.1.1.7, MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN] xref: EC:1.1.1.7 xref: GO:0050216 xref: MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007570 name: propioin synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 propanal = 4-hydroxy-3-hexanone." [EC:4.1.2.35, MetaCyc:PROPIOIN-SYNTHASE-RXN] synonym: "4-hydroxy-3-hexanone aldolase activity" EXACT [EC:4.1.2.35] synonym: "4-hydroxy-3-hexanone propanal-lyase (propanal-forming)" EXACT [EC:4.1.2.35] synonym: "4-hydroxy-3-hexanone propanal-lyase activity" EXACT [EC:4.1.2.35] xref: EC:4.1.2.35 xref: GO:0050217 xref: MetaCyc:PROPIOIN-SYNTHASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007571 name: propionate-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA." [EC:6.2.1.17, MetaCyc:PROPIONATE--COA-LIGASE-RXN] subset: gosubset_prok synonym: "propanoate:CoA ligase (AMP-forming)" EXACT [EC:6.2.1.17] synonym: "propionyl-CoA synthetase activity" EXACT [EC:6.2.1.17] xref: EC:6.2.1.17 xref: GO:0050218 xref: MetaCyc:PROPIONATE--COA-LIGASE-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007572 name: prostaglandin-A1 delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate = (13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate." [EC:5.3.3.9, MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN] synonym: "(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate delta10-delta11-isomerase activity" EXACT [EC:5.3.3.9] synonym: "prostaglandin A isomerase activity" EXACT [EC:5.3.3.9] synonym: "prostaglandin-A1 D-isomerase activity" EXACT [] xref: EC:5.3.3.9 xref: GO:0050219 xref: MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0007573 name: prostaglandin-E synthase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate." [EC:5.3.99.3, MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN] synonym: "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity" EXACT [EC:5.3.99.3] synonym: "endoperoxide isomerase activity" EXACT [EC:5.3.99.3] synonym: "PGE isomerase activity" EXACT [EC:5.3.99.3] synonym: "PGE2 isomerase activity" EXACT [EC:5.3.99.3] synonym: "PGH-PGE isomerase activity" EXACT [EC:5.3.99.3] synonym: "prostaglandin endoperoxide E isomerase activity" EXACT [EC:5.3.99.3] synonym: "prostaglandin endoperoxide E2 isomerase activity" EXACT [EC:5.3.99.3] synonym: "prostaglandin H-E isomerase activity" EXACT [EC:5.3.99.3] synonym: "prostaglandin R-prostaglandin E isomerase activity" EXACT [EC:5.3.99.3] synonym: "Prostaglandin-H(2) E-isomerase activity" EXACT [EC:5.3.99.3] synonym: "prostaglandin-H2 E-isomerase activity" EXACT [EC:5.3.99.3] xref: EC:5.3.99.3 xref: GO:0050220 xref: MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0007574 name: prostaglandin-E2 9-reductase activity namespace: molecular_function def: "Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH." [EC:1.1.1.189, MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN] synonym: "(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity" EXACT [EC:1.1.1.189] synonym: "9-keto-prostaglandin E(2) reductase activity" EXACT [EC:1.1.1.189] synonym: "9-keto-prostaglandin E2 reductase activity" EXACT [EC:1.1.1.189] synonym: "9-ketoprostaglandin reductase activity" EXACT [EC:1.1.1.189] synonym: "PGE(2) 9-ketoreductase activity" EXACT [EC:1.1.1.189] synonym: "PGE(2) 9-oxoreductase activity" EXACT [EC:1.1.1.189] synonym: "PGE-9-ketoreductase activity" EXACT [EC:1.1.1.189] synonym: "PGE2 9-ketoreductase activity" EXACT [EC:1.1.1.189] synonym: "PGE2 9-oxoreductase activity" EXACT [EC:1.1.1.189] synonym: "PGE2-9-ketoreductase activity" EXACT [EC:1.1.1.189] synonym: "PGE2-9-OR" RELATED [EC:1.1.1.189] synonym: "prostaglandin E 9-ketoreductase activity" EXACT [EC:1.1.1.189] synonym: "prostaglandin E2-9-oxoreductase activity" EXACT [EC:1.1.1.189] synonym: "prostaglandin-E(2) 9-oxoreductase activity" EXACT [EC:1.1.1.189] synonym: "prostaglandin-E2 9-oxoreductase activity" EXACT [EC:1.1.1.189] synonym: "reductase, 15-hydroxy-9-oxoprostaglandin" EXACT [EC:1.1.1.189] xref: EC:1.1.1.189 xref: GO:0050221 xref: MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007575 name: protocatechuate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxybenzoate = catechol + CO2." [EC:4.1.1.63, MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN] synonym: "3,4-dihydrobenzoate decarboxylase activity" EXACT [EC:4.1.1.63] synonym: "3,4-dihydroxybenzoate carboxy-lyase (catechol-forming)" EXACT [EC:4.1.1.63] synonym: "3,4-dihydroxybenzoate decarboxylase activity" EXACT [EC:4.1.1.63] synonym: "protocatechuate carboxy-lyase activity" EXACT [EC:4.1.1.63] xref: EC:4.1.1.63 xref: GO:0050223 xref: MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007576 name: prunasin beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-prunasin + H2O = D-glucose + mandelonitrile." [EC:3.2.1.118, MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN] synonym: "prunasin b-glucosidase activity" EXACT [] synonym: "prunasin beta-D-glucohydrolase activity" EXACT [EC:3.2.1.118] synonym: "prunasin hydrolase activity" EXACT [EC:3.2.1.118] xref: EC:3.2.1.118 xref: GO:0050224 xref: MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007577 name: pseudouridine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pseudouridine = ADP + pseudouridine 5'-phosphate." [EC:2.7.1.83, MetaCyc:PSEUDOURIDINE-KINASE-RXN] synonym: "ATP:pseudouridine 5'-phosphotransferase activity" EXACT [EC:2.7.1.83] synonym: "pseudouridine kinase (phosphorylating)" EXACT [EC:2.7.1.83] xref: EC:2.7.1.83 xref: GO:0050225 xref: MetaCyc:PSEUDOURIDINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007578 name: psychosine sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate." [EC:2.8.2.13, MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity" EXACT [EC:2.8.2.13] synonym: "3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase activity" EXACT [EC:2.8.2.13] synonym: "PAPS:psychosine sulphotransferase activity" EXACT [EC:2.8.2.13] synonym: "psychosine sulphotransferase activity" EXACT [] xref: EC:2.8.2.13 xref: GO:0050226 xref: MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007579 name: pteridine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown." [EC:1.17.3.1, MetaCyc:PTERIDINE-OXIDASE-RXN] synonym: "2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating)" EXACT [EC:1.17.3.1] xref: EC:1.17.3.1 xref: GO:0050227 xref: MetaCyc:PTERIDINE-OXIDASE-RXN is_a: CCO:F0003309 ! oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor [Term] id: CCO:F0007580 name: pterin deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3." [EC:3.5.4.11, MetaCyc:PTERIN-DEAMINASE-RXN] synonym: "2-amino-4-hydroxypteridine aminohydrolase activity" EXACT [EC:3.5.4.11] synonym: "acrasinase activity" EXACT [EC:3.5.4.11] xref: EC:3.5.4.11 xref: GO:0050228 xref: MetaCyc:PTERIN-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007581 name: pterocarpin synthase activity namespace: molecular_function def: "Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH." [EC:1.1.1.246, MetaCyc:PTEROCARPIN-SYNTHASE-RXN] synonym: "medicarpin:NADP+ 2'-oxidoreductase activity" EXACT [EC:1.1.1.246] synonym: "pterocarpan synthase activity" EXACT [EC:1.1.1.246] xref: EC:1.1.1.246 xref: GO:0050229 xref: MetaCyc:PTEROCARPIN-SYNTHASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007582 name: purine imidazole-ring cyclase activity namespace: molecular_function def: "Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O." [EC:4.3.2.4, MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN] synonym: "DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing)" EXACT [EC:4.3.2.4] synonym: "DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming)" EXACT [EC:4.3.2.4] synonym: "DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming)" EXACT [EC:4.3.2.4] xref: EC:4.3.2.4 xref: GO:0050230 xref: MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN is_a: CCO:F0002427 ! cyclase activity is_a: CCO:F0003407 ! amidine-lyase activity [Term] id: CCO:F0007583 name: putrescine carbamoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine." [EC:2.1.3.6, MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN] subset: gosubset_prok synonym: "carbamoyl-phosphate:putrescine carbamoyltransferase activity" EXACT [EC:2.1.3.6] synonym: "PTCase activity" EXACT [EC:2.1.3.6] synonym: "putrescine synthase activity" EXACT [EC:2.1.3.6] synonym: "putrescine transcarbamylase activity" EXACT [EC:2.1.3.6] xref: EC:2.1.3.6 xref: GO:0050231 xref: MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN is_a: CCO:F0003319 ! carboxyl- or carbamoyltransferase activity [Term] id: CCO:F0007584 name: putrescine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2." [EC:1.4.3.10, MetaCyc:PUTRESCINE-OXIDASE-RXN] subset: gosubset_prok synonym: "putrescine:oxygen oxidoreductase (deaminating)" EXACT [EC:1.4.3.10] xref: EC:1.4.3.10 xref: GO:0050232 xref: MetaCyc:PUTRESCINE-OXIDASE-RXN is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0007585 name: pyranose oxidase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose + O2 = 2-dehydro-D-glucose + H2O2." [EC:1.1.3.10, MetaCyc:PYRANOSE-OXIDASE-RXN] synonym: "glucose 2-oxidase activity" EXACT [EC:1.1.3.10] synonym: "pyranose-2-oxidase activity" EXACT [EC:1.1.3.10] synonym: "pyranose:oxygen 2-oxidoreductase activity" EXACT [EC:1.1.3.10] xref: EC:1.1.3.10 xref: GO:0050233 xref: MetaCyc:PYRANOSE-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007586 name: pyrazolylalanine synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H2O." [EC:4.2.1.50, MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN] synonym: "beta-pyrazolylalaninase activity" EXACT [EC:4.2.1.50] synonym: "L-serine hydro-lyase (adding pyrazole)" EXACT [EC:4.2.1.50] synonym: "L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]" RELATED [EC:4.2.1.50] xref: EC:4.2.1.50 xref: GO:0050234 xref: MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007587 name: pyridoxal 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxal + NAD+ = 4-pyridoxolactone + NADH." [EC:1.1.1.107, MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN] synonym: "pyridoxal dehydrogenase activity" EXACT [EC:1.1.1.107] synonym: "pyridoxal:NAD+ 4-oxidoreductase activity" EXACT [EC:1.1.1.107] xref: EC:1.1.1.107 xref: GO:0050235 xref: MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007588 name: pyridoxine 4-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxine + NADP+ = pyridoxal + NADPH." [EC:1.1.1.65, MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN] synonym: "PL reductase activity" EXACT [EC:1.1.1.65] synonym: "pyridoxal reductase activity" EXACT [EC:1.1.1.65] synonym: "pyridoxin dehydrogenase activity" EXACT [EC:1.1.1.65] synonym: "pyridoxine dehydrogenase activity" EXACT [EC:1.1.1.65] synonym: "pyridoxine:NADP+ 4-oxidoreductase activity" EXACT [EC:1.1.1.65] synonym: "pyridoxol dehydrogenase activity" EXACT [EC:1.1.1.65] xref: EC:1.1.1.65 xref: GO:0050236 xref: MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN is_a: CCO:F0000511 ! aldo-keto reductase activity [Term] id: CCO:F0007589 name: pyridoxine 4-oxidase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2." [EC:1.1.3.12, MetaCyc:PYRIDOXINE-4-OXIDASE-RXN] synonym: "pyridoxin 4-oxidase activity" EXACT [EC:1.1.3.12] synonym: "pyridoxine:oxygen 4-oxidoreductase activity" EXACT [EC:1.1.3.12] synonym: "pyridoxol 4-oxidase activity" EXACT [EC:1.1.3.12] xref: EC:1.1.3.12 xref: GO:0050237 xref: MetaCyc:PYRIDOXINE-4-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007590 name: pyridoxine 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor." [EC:1.1.99.9, MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN] synonym: "pyridoxal-5-dehydrogenase activity" EXACT [EC:1.1.99.9] synonym: "pyridoxin 5-dehydrogenase activity" EXACT [EC:1.1.99.9] synonym: "pyridoxine 5'-dehydrogenase activity" EXACT [EC:1.1.99.9] synonym: "pyridoxine:(acceptor) 5-oxidoreductase activity" EXACT [EC:1.1.99.9] synonym: "pyridoxine:acceptor 5-oxidoreductase activity" EXACT [EC:1.1.99.9] synonym: "pyridoxol 5-dehydrogenase activity" EXACT [EC:1.1.99.9] xref: EC:1.1.99.9 xref: GO:0050238 xref: MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007591 name: pyrithiamine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3." [EC:3.5.4.20, MetaCyc:PYRITHIAMIN-DEAMINASE-RXN] synonym: "1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase activity" EXACT [EC:3.5.4.20] xref: EC:3.5.4.20 xref: GO:0050239 xref: MetaCyc:PYRITHIAMIN-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007592 name: pyrogallol 1,2-oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2,3-trihydroxybenzene + O2 = (Z)-5-oxohex-2-enedioate." [EC:1.13.11.35, MetaCyc:PYROGALLOL-1] synonym: "1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.35] synonym: "pyrogallol 1,2-dioxygenase activity" EXACT [EC:1.13.11.35] xref: EC:1.13.11.35 xref: GO:0050240 xref: MetaCyc:PYROGALLOL-1 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007593 name: pyrroline-2-carboxylate reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+." [EC:1.5.1.1, MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN] synonym: "delta1-pyrroline-2-carboxylate reductase activity" EXACT [EC:1.5.1.1] synonym: "L-proline:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.5.1.1] xref: EC:1.5.1.1 xref: GO:0050241 xref: MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007594 name: pyruvate, phosphate dikinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + pyruvate + phosphate = AMP + phosphoenolpyruvate + diphosphate." [EC:2.7.9.1, MetaCyc:PYRUVATE] subset: gosubset_prok synonym: "ATP:pyruvate, phosphate phosphotransferase activity" EXACT [EC:2.7.9.1] synonym: "orthophosphate dikinase pyruvate" RELATED [EC:2.7.9.1] synonym: "PPDK" RELATED [EC:2.7.9.1] synonym: "pyruvate, Pi dikinase activity" EXACT [EC:2.7.9.1] synonym: "pyruvate,orthophosphate dikinase activity" EXACT [EC:2.7.9.1] synonym: "pyruvate,phosphate dikinase activity" EXACT [EC:2.7.9.1] synonym: "pyruvate-inorganic phosphate dikinase activity" EXACT [EC:2.7.9.1] synonym: "pyruvate-phosphate dikinase (phosphorylating)" EXACT [EC:2.7.9.1] synonym: "pyruvate-phosphate dikinase activity" EXACT [EC:2.7.9.1] synonym: "pyruvate-phosphate ligase activity" EXACT [EC:2.7.9.1] synonym: "pyruvic-phosphate dikinase activity" EXACT [EC:2.7.9.1] synonym: "pyruvic-phosphate ligase activity" EXACT [EC:2.7.9.1] xref: EC:2.7.9.1 xref: GO:0050242 xref: MetaCyc:PYRUVATE is_a: CCO:F0003353 ! phosphotransferase activity, paired acceptors [Term] id: CCO:F0007595 name: pyruvate dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH." [EC:1.2.1.51, MetaCyc:PYRUVATE-DEHYDROGENASE-(NADP+)-RXN] synonym: "pyruvate:NADP(+) oxidoreductase activity" EXACT [EC:1.2.1.51] synonym: "pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.1.51] synonym: "pyruvate:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.51] xref: EC:1.2.1.51 xref: GO:0050243 xref: MetaCyc:PYRUVATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0008473 ! pyruvate dehydrogenase [NAD(P)+] activity [Term] id: CCO:F0007596 name: pyruvate oxidase (CoA-acetylating) activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + CoA + O2 = acetyl-CoA + CO2 + H2O2." [EC:1.2.3.6, MetaCyc:PYRUVATE-OXIDASE-(COA-ACETYLATING)-RXN] synonym: "pyruvate:oxygen 2-oxidoreductase (CoA-acetylating)" EXACT [EC:1.2.3.6] xref: EC:1.2.3.6 xref: GO:0050244 xref: MetaCyc:PYRUVATE-OXIDASE-(COA-ACETYLATING)-RXN is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0007597 name: quercitrinase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + quercitrin = L-rhamnose + quercetin." [EC:3.2.1.66, MetaCyc:QUERCITRINASE-RXN] synonym: "quercitrin 3-L-rhamnohydrolase activity" EXACT [EC:3.2.1.66] xref: EC:3.2.1.66 xref: GO:0050245 xref: MetaCyc:QUERCITRINASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007598 name: questin monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: questin + NADPH + O2 = sulochrin + NADP+ + H2O." [EC:1.14.13.43, MetaCyc:QUESTIN-MONOOXYGENASE-RXN] synonym: "questin oxygenase activity" EXACT [EC:1.14.13.43] synonym: "questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)" EXACT [EC:1.14.13.43] xref: EC:1.14.13.43 xref: GO:0050246 xref: MetaCyc:QUESTIN-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007599 name: raucaffricine beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + raucaffricine = D-glucose + vomilenine." [EC:3.2.1.125, MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN] synonym: "raucaffricine b-glucosidase activity" EXACT [] synonym: "raucaffricine beta-D-glucohydrolase activity" EXACT [EC:3.2.1.125] synonym: "raucaffricine beta-D-glucosidase activity" EXACT [EC:3.2.1.125] synonym: "raucaffricine glucosidase activity" EXACT [EC:3.2.1.125] xref: EC:3.2.1.125 xref: GO:0050247 xref: MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007600 name: Renilla-luciferin 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light." [EC:1.13.12.5, MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN] synonym: "aequorin activity" NARROW [EC:1.13.12.5] synonym: "luciferase (Renilla luciferin)" EXACT [EC:1.13.12.5] synonym: "luciferase activity" BROAD [EC:1.13.12.5] synonym: "Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.5] synonym: "Renilla-type luciferase activity" EXACT [EC:1.13.12.5] synonym: "renilla-type luciferase activity" EXACT [EC:1.13.12.5] xref: EC:1.13.12.5 xref: GO:0050248 xref: MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) is_a: CCO:F0006100 ! luciferin monooxygenase activity [Term] id: CCO:F0007601 name: Renilla-luciferin sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + Renilla luciferin = adenosine 3',5'-bisphosphate + luciferyl sulfate." [EC:2.8.2.10, MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity" EXACT [EC:2.8.2.10] synonym: "luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)" EXACT [EC:2.8.2.10] synonym: "luciferin sulfokinase activity" EXACT [EC:2.8.2.10] synonym: "luciferin sulfotransferase activity" BROAD [EC:2.8.2.10] synonym: "Renilla-luciferin sulphotransferase activity" EXACT [] xref: EC:2.8.2.10 xref: GO:0050249 xref: MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007602 name: retinal oxidase activity namespace: molecular_function def: "Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2." [EC:1.2.3.11, MetaCyc:RETINAL-OXIDASE-RXN] synonym: "retinal:oxygen oxidoreductase activity" EXACT [EC:1.2.3.11] synonym: "retinene oxidase activity" RELATED [EC:1.2.3.11] xref: EC:1.2.3.11 xref: GO:0050250 xref: MetaCyc:RETINAL-OXIDASE-RXN is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0007603 name: retinol isomerase activity namespace: molecular_function def: "Catalysis of the reaction: all-trans-retinol = 11-cis-retinol." [EC:5.2.1.7, MetaCyc:RETINOL-ISOMERASE-RXN] synonym: "all-trans-retinol 11-cis-trans-isomerase activity" EXACT [EC:5.2.1.7] synonym: "all-trans-retinol isomerase activity" EXACT [EC:5.2.1.7] xref: EC:5.2.1.7 xref: GO:0050251 xref: MetaCyc:RETINOL-ISOMERASE-RXN is_a: CCO:F0003421 ! cis-trans isomerase activity [Term] id: CCO:F0007604 name: retinol O-fatty-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester." [EC:2.3.1.76, MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN] synonym: "acyl-CoA:retinol O-acyltransferase activity" EXACT [EC:2.3.1.76] synonym: "retinol acyltransferase activity" EXACT [EC:2.3.1.76] synonym: "retinol fatty-acyltransferase activity" EXACT [EC:2.3.1.76] xref: EC:2.3.1.76 xref: GO:0050252 xref: MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0007605 name: retinyl-palmitate esterase activity namespace: molecular_function def: "Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate." [EC:3.1.1.21, MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN] synonym: "retinyl ester hydrolase activity" EXACT [EC:3.1.1.21] synonym: "retinyl palmitate hydrolase activity" EXACT [EC:3.1.1.21] synonym: "retinyl palmitate hydrolyase activity" EXACT [EC:3.1.1.21] synonym: "retinyl-palmitate palmitohydrolase activity" EXACT [EC:3.1.1.21] xref: EC:3.1.1.21 xref: GO:0050253 xref: MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007606 name: rhodopsin kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin." [EC:2.7.11.14, MetaCyc:RHODOPSIN-KINASE-RXN] synonym: "ATP:rhodopsin phosphotransferase activity" EXACT [EC:2.7.11.14] synonym: "cone opsin kinase activity" NARROW [EC:2.7.11.14] synonym: "G-protein-coupled receptor kinase 1 activity" NARROW [EC:2.7.11.14] synonym: "GPCR kinase 1 activity" NARROW [EC:2.7.11.14] synonym: "GRK1" RELATED [EC:2.7.11.14] synonym: "GRK7" RELATED [EC:2.7.11.14] synonym: "opsin kinase (phosphorylating) activity" EXACT [EC:2.7.11.14] synonym: "opsin kinase activity" EXACT [EC:2.7.11.14] synonym: "rhodopsin kinase (phosphorylating) activity" EXACT [EC:2.7.11.14] synonym: "RK" RELATED [EC:2.7.11.14] synonym: "STK14" RELATED [EC:2.7.11.14] xref: EC:2.7.11.14 xref: GO:0050254 xref: MetaCyc:RHODOPSIN-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0007607 name: ribitol 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: ribitol + NAD+ = D-ribulose + NADH." [EC:1.1.1.56, MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "adonitol dehydrogenase activity" EXACT [EC:1.1.1.56] synonym: "ribitol dehydrogenase A (wild type)" RELATED [EC:1.1.1.56] synonym: "ribitol dehydrogenase B (mutant enzyme with different properties)" RELATED [EC:1.1.1.56] synonym: "ribitol dehydrogenase D (mutant enzyme with different properties)" RELATED [EC:1.1.1.56] synonym: "ribitol:NAD+ 2-oxidoreductase activity" EXACT [EC:1.1.1.56] xref: EC:1.1.1.56 xref: GO:0050255 xref: MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007608 name: ribitol-5-phosphate 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+." [EC:1.1.1.137, MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.137] synonym: "dehydrogenase, ribitol 5-phosphate" EXACT [EC:1.1.1.137] xref: EC:1.1.1.137 xref: GO:0050256 xref: MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007609 name: riboflavin phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucose 1-phosphate + riboflavin = D-glucose + FMN." [EC:2.7.1.42, MetaCyc:RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN] synonym: "alpha-D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity" EXACT [EC:2.7.1.42] synonym: "D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity" EXACT [EC:2.7.1.42] synonym: "G-1-P phosphotransferase activity" EXACT [EC:2.7.1.42] synonym: "riboflavine phosphotransferase activity" EXACT [EC:2.7.1.42] xref: EC:2.7.1.42 xref: GO:0050257 xref: MetaCyc:RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007610 name: riboflavinase activity namespace: molecular_function def: "Catalysis of the reaction: riboflavin + H2O = ribitol + lumichrome." [EC:3.5.99.1, MetaCyc:RIBOFLAVINASE-RXN] synonym: "riboflavin hydrolase activity" EXACT [EC:3.5.99.1] xref: EC:3.5.99.1 xref: GO:0050258 xref: MetaCyc:RIBOFLAVINASE-RXN is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0007611 name: ribose 1-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: D-ribose + NADP+ + H2O = D-ribonate + NADPH." [EC:1.1.1.115, MetaCyc:RIBOSE-1-DEHYDROGENASE-(NADP+)-RXN] synonym: "D-ribose dehydrogenase (NADP+)" EXACT [EC:1.1.1.115] synonym: "D-ribose:NADP+ 1-oxidoreductase activity" EXACT [EC:1.1.1.115] synonym: "NADP-pentose-dehydrogenase activity" EXACT [EC:1.1.1.115] xref: EC:1.1.1.115 xref: GO:0050259 xref: MetaCyc:RIBOSE-1-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007612 name: ribose-5-phosphate-ammonia ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + ribose 5-phosphate + NH3 = ADP + phosphate + 5-phosphoribosylamine." [EC:6.3.4.7, MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN] synonym: "5-phosphoribosylamine synthetase activity" EXACT [EC:6.3.4.7] synonym: "ammonia-ribose 5-phosphate aminotransferase activity" EXACT [EC:6.3.4.7] synonym: "ribose 5-phosphate aminotransferase activity" EXACT [EC:6.3.4.7] synonym: "ribose-5-phosphate:ammonia ligase (ADP-forming)" EXACT [EC:6.3.4.7] xref: EC:6.3.4.7 xref: GO:0050260 xref: MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0007613 name: ribose isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribose = D-ribulose." [EC:5.3.1.20, MetaCyc:RIBOSE-ISOMERASE-RXN] synonym: "D-ribose aldose-ketose-isomerase activity" EXACT [EC:5.3.1.20] synonym: "D-ribose isomerase activity" EXACT [EC:5.3.1.20] synonym: "D-ribose ketol-isomerase activity" EXACT [EC:5.3.1.20] xref: EC:5.3.1.20 xref: GO:0050261 xref: MetaCyc:RIBOSE-ISOMERASE-RXN is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0007614 name: ribosylnicotinamide kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + N-ribosylnicotinamide = ADP + nicotinamide ribonucleotide." [EC:2.7.1.22, MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN] synonym: "ATP:N-ribosylnicotinamide 5'-phosphotransferase activity" EXACT [EC:2.7.1.22] synonym: "ribosylnicotinamide kinase (phosphorylating)" EXACT [EC:2.7.1.22] xref: EC:2.7.1.22 xref: GO:0050262 xref: MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007615 name: ribosylpyrimidine nucleosidase activity namespace: molecular_function def: "Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine." [EC:3.2.2.8, MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN] synonym: "N-ribosylpyrimidine nucleosidase activity" EXACT [EC:3.2.2.8] synonym: "N-ribosylpyrimidine ribohydrolase activity" EXACT [EC:3.2.2.8] synonym: "nucleoside ribohydrolase activity" BROAD [EC:3.2.2.8] synonym: "pyrimidine nucleosidase activity" EXACT [EC:3.2.2.8] synonym: "pyrimidine-nucleoside ribohydrolase activity" EXACT [EC:3.2.2.8] synonym: "RihB" RELATED [EC:3.2.2.8] synonym: "YeiK" RELATED [EC:3.2.2.8] xref: EC:3.2.2.8 xref: GO:0050263 xref: MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN is_a: CCO:F0003369 ! hydrolase activity, hydrolyzing N-glycosyl compounds [Term] id: CCO:F0007616 name: rifamycin-B oxidase activity namespace: molecular_function def: "Catalysis of the reaction: rifamycin B + O2 = rifamycin O + H2O2." [EC:1.10.3.6, MetaCyc:RIFAMYCIN-B-OXIDASE-RXN] synonym: "rifamycin B oxidase activity" EXACT [EC:1.10.3.6] synonym: "rifamycin-B-oxidase activity" EXACT [] synonym: "rifamycin-B:oxygen oxidoreductase activity" EXACT [EC:1.10.3.6] xref: EC:1.10.3.6 xref: GO:0050264 xref: MetaCyc:RIFAMYCIN-B-OXIDASE-RXN is_a: CCO:F0003273 ! oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Term] id: CCO:F0007617 name: RNA uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1)." [EC:2.7.7.52, MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN] synonym: "terminal uridylyltransferase activity" EXACT [EC:2.7.7.52] synonym: "TUT activity" EXACT [EC:2.7.7.52] synonym: "UTP:RNA uridylyltransferase activity" EXACT [] xref: EC:2.7.7.52 xref: GO:0050265 xref: MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0007618 name: rosmarinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate." [EC:2.3.1.140, MetaCyc:ROSMARINATE-SYNTHASE-RXN] synonym: "4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase activity" EXACT [EC:2.3.1.140] synonym: "caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase activity" EXACT [EC:2.3.1.140] synonym: "caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase activity" EXACT [EC:2.3.1.140] synonym: "rosmarinic acid synthase activity" EXACT [EC:2.3.1.140] xref: EC:2.3.1.140 xref: GO:0050266 xref: MetaCyc:ROSMARINATE-SYNTHASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007619 name: rubber cis-polyprenylcistransferase activity namespace: molecular_function def: "Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit." [EC:2.5.1.20, MetaCyc:RUBBER-CIS-POLYPRENYLCISTRANSFERASE-RXN] synonym: "cis-prenyl transferase activity" EXACT [EC:2.5.1.20] synonym: "isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase activity" EXACT [EC:2.5.1.20] synonym: "poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase activity" EXACT [EC:2.5.1.20] synonym: "rubber allyltransferase activity" EXACT [EC:2.5.1.20] synonym: "rubber polymerase activity" EXACT [EC:2.5.1.20] synonym: "rubber prenyltransferase activity" EXACT [EC:2.5.1.20] synonym: "rubber transferase activity" BROAD [EC:2.5.1.20] xref: EC:2.5.1.20 xref: GO:0050267 xref: MetaCyc:RUBBER-CIS-POLYPRENYLCISTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007620 name: coniferyl-alcohol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH." [EC:1.1.1.194, MetaCyc:RXN-1107] synonym: "coniferyl-alcohol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.194] xref: EC:1.1.1.194 xref: GO:0050268 xref: MetaCyc:RXN-1107 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007621 name: coniferyl-aldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+." [EC:1.2.1.68, MetaCyc:RXN-1241] subset: gosubset_prok synonym: "coniferyl aldehyde:NAD(P)+ oxidoreductase activity" EXACT [EC:1.2.1.68] xref: EC:1.2.1.68 xref: GO:0050269 xref: MetaCyc:RXN-1241 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007622 name: S-adenosylhomocysteine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = S-inosyl-L-homocysteine + NH3." [EC:3.5.4.28, MetaCyc:S-ADENOSYLHOMOCYSTEINE-DEAMINASE-RXN] synonym: "adenosylhomocysteine deaminase activity" EXACT [EC:3.5.4.28] synonym: "S-adenosyl-L-homocysteine aminohydrolase activity" EXACT [EC:3.5.4.28] xref: EC:3.5.4.28 xref: GO:0050270 xref: MetaCyc:S-ADENOSYLHOMOCYSTEINE-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007623 name: S-alkylcysteine lyase activity namespace: molecular_function def: "Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate." [EC:4.4.1.6, MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN] synonym: "alkyl cysteine lyase activity" EXACT [EC:4.4.1.6] synonym: "alkylcysteine lyase activity" EXACT [EC:4.4.1.6] synonym: "S-alkyl-L-cysteinase activity" EXACT [EC:4.4.1.6] synonym: "S-alkyl-L-cysteine alkylthiol-lyase (deaminating) activity" EXACT [EC:4.4.1.6] synonym: "S-alkyl-L-cysteine alkylthiol-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.4.1.6] synonym: "S-alkyl-L-cysteine lyase activity" EXACT [EC:4.4.1.6] synonym: "S-alkyl-L-cysteine sulfoxide lyase activity" EXACT [EC:4.4.1.6] synonym: "S-alkylcysteinase activity" EXACT [EC:4.4.1.6] xref: EC:4.4.1.6 xref: GO:0050271 xref: MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007624 name: S-carboxymethylcysteine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride." [EC:4.5.1.5, MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN] synonym: "3-chloro-L-alanine chloride-lyase (adding thioglycolate)" EXACT [EC:4.5.1.5] synonym: "3-chloro-L-alanine chloride-lyase (adding thioglycolate; S-carboxymethyl-L-cysteine-forming)" EXACT [EC:4.5.1.5] synonym: "S-carboxymethyl-L-cysteine synthase activity" EXACT [EC:4.5.1.5] xref: EC:4.5.1.5 xref: GO:0050272 xref: MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN is_a: CCO:F0003412 ! carbon-halide lyase activity [Term] id: CCO:F0007625 name: S-succinylglutathione hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: S-succinylglutathione + H2O = glutathione + succinate." [EC:3.1.2.13, MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN] xref: EC:3.1.2.13 xref: GO:0050273 xref: MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0007626 name: salicyl-alcohol beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + salicyl alcohol = UDP + salicin." [EC:2.4.1.172, MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN] synonym: "salicyl-alcohol b-D-glucosyltransferase activity" EXACT [] synonym: "salicyl-alcohol glucosyltransferase activity" EXACT [] synonym: "UDP-glucose:salicyl-alcohol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.172] synonym: "UDPglucose:salicyl alcohol phenyl-glucosyltransferase activity" EXACT [EC:2.4.1.172] synonym: "UDPglucose:salicyl-alcohol beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.172] synonym: "uridine diphosphoglucose-salicyl alcohol 2-glucosyltransferase activity" EXACT [EC:2.4.1.172] xref: EC:2.4.1.172 xref: GO:0050274 xref: MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007627 name: scopoletin glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + scopoletin = UDP + scopolin." [EC:2.4.1.128, MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN] synonym: "SGTase activity" EXACT [EC:2.4.1.128] synonym: "UDP-glucose:scopoletin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.128] synonym: "UDPglucose:scopoletin glucosyltransferase activity" EXACT [EC:2.4.1.128] synonym: "UDPglucose:scopoletin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.128] synonym: "uridine diphosphoglucose-scopoletin glucosyltransferase activity" EXACT [EC:2.4.1.128] xref: EC:2.4.1.128 xref: GO:0050275 xref: MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007628 name: scyllo-inosamine 4-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 1-amino-1-deoxy-scyllo-inositol = ADP + 1-amino-1-deoxy-scyllo-inositol 4-phosphate." [EC:2.7.1.65, MetaCyc:SCYLLO-INOSAMINE-KINASE-RXN] synonym: "ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase activity" EXACT [EC:2.7.1.65] synonym: "ATP:inosamine phosphotransferase activity" EXACT [EC:2.7.1.65] synonym: "scyllo-inosamine kinase (phosphorylating)" EXACT [EC:2.7.1.65] synonym: "scyllo-inosamine kinase activity" EXACT [] xref: EC:2.7.1.65 xref: GO:0050276 xref: MetaCyc:SCYLLO-INOSAMINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007629 name: sedoheptulokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + sedoheptulose = ADP + sedoheptulose 7-phosphate." [EC:2.7.1.14, MetaCyc:SEDOHEPTULOKINASE-RXN] synonym: "ATP:sedoheptulose 7-phosphotransferase activity" EXACT [EC:2.7.1.14] synonym: "heptulokinase activity" EXACT [EC:2.7.1.14] synonym: "sedoheptulokinase (phosphorylating)" EXACT [EC:2.7.1.14] xref: EC:2.7.1.14 xref: GO:0050277 xref: MetaCyc:SEDOHEPTULOKINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007630 name: sedoheptulose-bisphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate." [EC:3.1.3.37, MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN] subset: gosubset_prok synonym: "SBPase activity" EXACT [EC:3.1.3.37] synonym: "sedoheptulose 1,7-bisphosphatase activity" EXACT [EC:3.1.3.37] synonym: "sedoheptulose 1,7-diphospate phosphatase activity" EXACT [EC:3.1.3.37] synonym: "sedoheptulose 1,7-diphosphatase activity" EXACT [EC:3.1.3.37] synonym: "sedoheptulose bisphosphatase activity" EXACT [EC:3.1.3.37] synonym: "sedoheptulose diphosphatase activity" EXACT [EC:3.1.3.37] synonym: "sedoheptulose-1,7-bisphosphatase activity" EXACT [EC:3.1.3.37] synonym: "sedoheptulose-1,7-bisphosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.37] xref: EC:3.1.3.37 xref: GO:0050278 xref: MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007631 name: sepiapterin deaminase activity namespace: molecular_function def: "Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3." [EC:3.5.4.24, MetaCyc:SEPIAPTERIN-DEAMINASE-RXN] synonym: "sepiapterin aminohydrolase activity" EXACT [EC:3.5.4.24] xref: EC:3.5.4.24 xref: GO:0050279 xref: MetaCyc:SEPIAPTERIN-DEAMINASE-RXN is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007632 name: sequoyitol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-O-methyl-myo-inositol + NAD+ = 5D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH." [EC:1.1.1.143, MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN] synonym: "5-O-methyl-myo-inositol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.143] xref: EC:1.1.1.143 xref: GO:0050280 xref: MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007633 name: serine-glyoxylate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine." [EC:2.6.1.45, MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN] subset: gosubset_prok synonym: "L-serine:glyoxylate aminotransferase activity" EXACT [EC:2.6.1.45] synonym: "serine--glyoxylate aminotransferase activity" EXACT [] synonym: "SGAT activity" EXACT [EC:2.6.1.45] xref: EC:2.6.1.45 xref: GO:0050281 xref: MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007634 name: serine 2-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH." [EC:1.4.1.7, MetaCyc:SERINE-DEHYDROGENASE-RXN] synonym: "L-serine:NAD oxidoreductase (deaminating) activity" EXACT [EC:1.4.1.7] synonym: "L-serine:NAD+ 2-oxidoreductase (deaminating)" EXACT [EC:1.4.1.7] synonym: "serine dehydrogenase activity" EXACT [] xref: EC:1.4.1.7 xref: GO:0050282 xref: MetaCyc:SERINE-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007635 name: serine-sulfate ammonia-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + SO4(2-) (sulfate)." [EC:4.3.1.10, MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN] synonym: "(L-SOS)lyase activity" EXACT [EC:4.3.1.10] synonym: "L-serine-O-sulfate ammonia-lyase (pyruvate-forming)" EXACT [EC:4.3.1.10] synonym: "serine-sulphate ammonia-lyase activity" EXACT [] xref: EC:4.3.1.10 xref: GO:0050283 xref: MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN is_a: CCO:F0003406 ! ammonia-lyase activity [Term] id: CCO:F0007636 name: sinapate 1-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose." [EC:2.4.1.120, MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN] synonym: "UDP-glucose:sinapate D-glucosyltransferase activity" EXACT [EC:2.4.1.120] synonym: "UDPglucose:sinapate D-glucosyltransferase activity" EXACT [EC:2.4.1.120] synonym: "UDPglucose:sinapic acid glucosyltransferase activity" EXACT [EC:2.4.1.120] synonym: "uridine 5'-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase activity" EXACT [EC:2.4.1.120] synonym: "uridine diphosphoglucose-sinapate glucosyltransferase activity" EXACT [EC:2.4.1.120] xref: EC:2.4.1.120 xref: GO:0050284 xref: MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007637 name: sinapine esterase activity namespace: molecular_function def: "Catalysis of the reaction: sinapoylcholine + H2O = sinapate + choline." [EC:3.1.1.49, MetaCyc:SINAPINE-ESTERASE-RXN] synonym: "aromatic choline esterase activity" EXACT [EC:3.1.1.49] synonym: "sinapoylcholine sinapohydrolase activity" EXACT [EC:3.1.1.49] xref: EC:3.1.1.49 xref: GO:0050285 xref: MetaCyc:SINAPINE-ESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007638 name: sorbitol-6-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: sorbitol 6-phosphate + H2O = sorbitol + phosphate." [EC:3.1.3.50, MetaCyc:SORBITOL-6-PHOSPHATASE-RXN] synonym: "sorbitol-6-phosphate phosphatase activity" EXACT [EC:3.1.3.50] synonym: "sorbitol-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.50] xref: EC:3.1.3.50 xref: GO:0050286 xref: MetaCyc:SORBITOL-6-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007639 name: sorbose 5-dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: L-sorbose + NADP+ = 5-dehydro-D-fructose + NADPH." [EC:1.1.1.123, MetaCyc:SORBOSE-5-DEHYDROGENASE-(NADP+)-RXN] synonym: "5-keto-D-fructose reductase activity" EXACT [EC:1.1.1.123] synonym: "5-ketofructose reductase activity" EXACT [EC:1.1.1.123] synonym: "L-sorbose:NADP+ 5-oxidoreductase activity" EXACT [EC:1.1.1.123] synonym: "reduced nicotinamide adenine dinucleotide phosphate-linked reductase activity" EXACT [EC:1.1.1.123] synonym: "sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" EXACT [EC:1.1.1.123] xref: EC:1.1.1.123 xref: GO:0050287 xref: MetaCyc:SORBOSE-5-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007640 name: sorbose dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-sorbose + acceptor = 5-dehydro-D-fructose + reduced acceptor." [EC:1.1.99.12, MetaCyc:SORBOSE-DEHYDROGENASE-RXN] synonym: "L-sorbose:(acceptor) 5-oxidoreductase activity" EXACT [EC:1.1.99.12] synonym: "L-sorbose:acceptor 5-oxidoreductase activity" EXACT [EC:1.1.99.12] xref: EC:1.1.99.12 xref: GO:0050288 xref: MetaCyc:SORBOSE-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007641 name: spermidine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor." [EC:1.5.99.6, MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN] synonym: "spermidine:(acceptor) oxidoreductase activity" EXACT [EC:1.5.99.6] synonym: "spermidine:acceptor oxidoreductase activity" EXACT [EC:1.5.99.6] xref: EC:1.5.99.6 xref: GO:0050289 xref: MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0007642 name: sphingomyelin phosphodiesterase D activity namespace: molecular_function def: "Catalysis of the reaction: sphingomyelin + H2O = ceramide phosphate + choline." [EC:3.1.4.41, MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN] synonym: "sphingomyelin ceramide-phosphohydrolase activity" EXACT [EC:3.1.4.41] synonym: "sphingomyelinase D" RELATED [EC:3.1.4.41] xref: EC:3.1.4.41 xref: GO:0050290 xref: MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN is_a: CCO:F0000999 ! phospholipase activity is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0007643 name: sphingosine N-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae, either dihydrosphingosine (DHS) or phytosphingosine (PHS) can react with C26-fattyacyl-CoA to produce ceramide-I or ceramide-II (also called phytoceramide) respectively. In mammals, DHS is usually acylated with a C18 fatty acid group." [EC:2.3.1.24, MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN, PMID:12069845] synonym: "acyl-CoA:sphingosine N-acyltransferase activity" EXACT [EC:2.3.1.24] synonym: "ceramide synthase activity" EXACT [] synonym: "ceramide synthetase activity" EXACT [EC:2.3.1.24] synonym: "dihydroceramide synthase activity" EXACT [] synonym: "sphingosine acyltransferase activity" EXACT [EC:2.3.1.24] xref: EC:2.3.1.24 xref: GO:0050291 xref: MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0007644 name: steroid 9-alpha-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: pregna-4,9(11)-diene-3,20-dione + donor-H2 + O2 = 9,11-alpha-epoxypregn-4-ene-3,20-dione + acceptor + H2O." [EC:1.14.99.24, MetaCyc:STEROID-9-ALPHA-MONOOXYGENASE-RXN] synonym: "steroid 9-alpha-hydroxylase activity" EXACT [EC:1.14.99.24] synonym: "steroid 9a-monooxygenase activity" EXACT [] synonym: "steroid 9alpha-hydroxylase activity" EXACT [EC:1.14.99.24] synonym: "steroid 9alpha-monooxygenase activity" EXACT [EC:1.14.99.24] synonym: "steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)" EXACT [EC:1.14.99.24] xref: EC:1.14.99.24 xref: GO:0050292 xref: MetaCyc:STEROID-9-ALPHA-MONOOXYGENASE-RXN is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007645 name: steroid-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: testololactone + H2O = testolate." [EC:3.1.1.37, MetaCyc:STEROID-LACTONASE-RXN] synonym: "testololactone lactonohydrolase activity" EXACT [EC:3.1.1.37] xref: EC:3.1.1.37 xref: GO:0050293 xref: MetaCyc:STEROID-LACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007646 name: steroid sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate." [EC:2.8.2.15, MetaCyc:STEROID-SULFOTRANSFERASE-RXN] synonym: "3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase activity" EXACT [EC:2.8.2.15] synonym: "steroid alcohol sulfotransferase" BROAD [EC:2.8.2.15] synonym: "steroid sulphotransferase activity" EXACT [] xref: EC:2.8.2.15 xref: GO:0050294 xref: MetaCyc:STEROID-SULFOTRANSFERASE-RXN xref: Reactome:80520 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007647 name: steryl-beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + cholesteryl-beta-D-glucoside = D-glucose + cholesterol." [EC:3.2.1.104, MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN] synonym: "cholesteryl-beta-D-glucoside glucohydrolase activity" EXACT [EC:3.2.1.104] synonym: "steryl-b-glucosidase activity" EXACT [] xref: EC:3.2.1.104 xref: GO:0050295 xref: MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007648 name: stipitatonate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: stipitatonate = stipitatate + CO2." [EC:4.1.1.60, MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN] synonym: "stipitatonate carboxy-lyase (decyclizing)" EXACT [EC:4.1.1.60] synonym: "stipitatonate carboxy-lyase (decyclizing, stipitatate-forming)" EXACT [EC:4.1.1.60] xref: EC:4.1.1.60 xref: GO:0050296 xref: MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007649 name: stizolobate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde." [EC:1.13.11.29, MetaCyc:STIZOLOBATE-SYNTHASE-RXN] synonym: "3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing)" EXACT [EC:1.13.11.29] xref: EC:1.13.11.29 xref: GO:0050297 xref: MetaCyc:STIZOLOBATE-SYNTHASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007650 name: stizolobinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde." [EC:1.13.11.30, MetaCyc:STIZOLOBINATE-SYNTHASE-RXN] synonym: "3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing)" EXACT [EC:1.13.11.30] xref: EC:1.13.11.30 xref: GO:0050298 xref: MetaCyc:STIZOLOBINATE-SYNTHASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007651 name: streptomycin 3''-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + streptomycin = ADP + streptomycin 3''-phosphate." [EC:2.7.1.87, MetaCyc:STREPTOMYCIN-3] subset: gosubset_prok synonym: "ATP:streptomycin 3''-phosphotransferase activity" EXACT [EC:2.7.1.87] synonym: "streptomycin 3''-kinase (phosphorylating)" EXACT [EC:2.7.1.87] synonym: "streptomycin 3''-phosphotransferase activity" EXACT [EC:2.7.1.87] xref: EC:2.7.1.87 xref: GO:0050299 xref: MetaCyc:STREPTOMYCIN-3 is_a: CCO:F0005515 ! aminoglycoside phosphotransferase activity [Term] id: CCO:F0007652 name: aminoglycoside 6-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + streptomycin = ADP + streptomycin 6-phosphate." [EC:2.7.1.72, MetaCyc:STREPTOMYCIN-6-KINASE-RXN] subset: gosubset_prok synonym: "APH(6) activity" EXACT [EC:2.7.1.72] synonym: "ATP:streptomycin 6-phosphotransferase activity" NARROW [EC:2.7.1.72] synonym: "SM 6-kinase activity" NARROW [EC:2.7.1.72] synonym: "streptidine kinase (phosphorylating)" NARROW [EC:2.7.1.72] synonym: "streptidine kinase activity" NARROW [EC:2.7.1.72] synonym: "streptomycin 6-kinase (phosphorylating)" NARROW [EC:2.7.1.72] synonym: "streptomycin 6-kinase activity" NARROW [] synonym: "streptomycin 6-O-phosphotransferase activity" NARROW [EC:2.7.1.72] synonym: "streptomycin 6-phosphotransferase activity" NARROW [EC:2.7.1.72] xref: EC:2.7.1.72 xref: GO:0050300 xref: MetaCyc:STREPTOMYCIN-6-KINASE-RXN is_a: CCO:F0005515 ! aminoglycoside phosphotransferase activity [Term] id: CCO:F0007653 name: streptomycin-6-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: streptomycin 6-phosphate + H2O = streptomycin + phosphate." [EC:3.1.3.39, MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN] subset: gosubset_prok synonym: "streptomycin 6-phosphate phosphatase activity" EXACT [EC:3.1.3.39] synonym: "streptomycin 6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.39] synonym: "streptomycin-6-P phosphohydrolase activity" EXACT [EC:3.1.3.39] synonym: "streptomycin-6-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.39] xref: EC:3.1.3.39 xref: GO:0050301 xref: MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007654 name: indole-3-acetaldehyde oxidase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + 2 indole acetaldehyde = 2 indole-3-acetic acid (IAA)." [EC:1.2.3.7, MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN] synonym: "(indol-3-yl)acetaldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.7] synonym: "AO1" RELATED [EC:1.2.3.7] synonym: "IAA oxidase activity" EXACT [EC:1.2.3.7] synonym: "IAAld oxidase activity" EXACT [EC:1.2.3.7] synonym: "indole-3-acetaldehyde:oxygen oxidoreductase activity" EXACT [EC:1.2.3.7] synonym: "indoleacetaldehyde oxidase activity" EXACT [EC:1.2.3.7] xref: EC:1.2.3.7 xref: GO:0050302 xref: MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN is_a: CCO:F0003685 ! aryl-aldehyde oxidase activity [Term] id: CCO:F0007655 name: lysine 6-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine." [EC:1.4.1.18, MetaCyc:LYSINE-6-DEHYDROGENASE-RXN] synonym: "L-lysine 6-dehydrogenase activity" EXACT [EC:1.4.1.18] synonym: "L-lysine epsilon-dehydrogenase activity" EXACT [EC:1.4.1.18] synonym: "L-lysine:NAD+ 6-oxidoreductase (deaminating)" EXACT [EC:1.4.1.18] synonym: "LysDH activity" EXACT [EC:1.4.1.18] xref: EC:1.4.1.18 xref: GO:0050303 xref: MetaCyc:LYSINE-6-DEHYDROGENASE-RXN xref: MetaCyc:PWY-5314 is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007656 name: nitrous-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: nitrogen + H2O + acceptor = nitrous oxide + reduced acceptor." [EC:1.7.99.6, MetaCyc:NITROUS-OXIDE-REDUCTASE-RXN] subset: gosubset_prok synonym: "N2O reductase activity" EXACT [EC:1.7.99.6] synonym: "nitrogen:(acceptor) oxidoreductase (N2O-forming)" EXACT [EC:1.7.99.6] synonym: "nitrogen:acceptor oxidoreductase (N2O-forming)" EXACT [EC:1.7.99.6] synonym: "nitrous oxide reductase activity" EXACT [EC:1.7.99.6] xref: EC:1.7.99.6 xref: GO:0050304 xref: MetaCyc:NITROUS-OXIDE-REDUCTASE-RXN is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0007657 name: strombine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: N-(carboxymethyl)-D-alanine + NAD+ + H2O = glycine + pyruvate + NADH." [EC:1.5.1.22, MetaCyc:STROMBINE-DEHYDROGENASE-RXN] synonym: "N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity" EXACT [EC:1.5.1.22] synonym: "N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)" EXACT [EC:1.5.1.22] synonym: "strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity" EXACT [EC:1.5.1.22] xref: EC:1.5.1.22 xref: GO:0050305 xref: MetaCyc:STROMBINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007658 name: sucrose 1F-fructosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose." [EC:2.4.1.99, MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN] synonym: "SST activity" EXACT [EC:2.4.1.99] synonym: "sucrose 1(F)-fructosyltransferase activity" EXACT [EC:2.4.1.99] synonym: "sucrose-sucrose 1-fructosyltransferase activity" EXACT [EC:2.4.1.99] synonym: "sucrose:sucrose 1'-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.99] synonym: "sucrose:sucrose 1(F)-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.99] synonym: "sucrose:sucrose 1-fructosyltransferase activity" EXACT [EC:2.4.1.99] synonym: "sucrose:sucrose 1F-beta-D-fructosyltransferase activity" EXACT [EC:2.4.1.99] synonym: "sucrose:sucrose fructosyltransferase activity" EXACT [EC:2.4.1.99] xref: EC:2.4.1.99 xref: GO:0050306 xref: MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN is_a: CCO:F0008006 ! fructosyltransferase activity [Term] id: CCO:F0007659 name: sucrose-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate." [EC:3.1.3.24, MetaCyc:SUCROSE-PHOSPHATASE-RXN] subset: gosubset_prok synonym: "sucrose 6-phosphate hydrolase activity" EXACT [EC:3.1.3.24] synonym: "sucrose-6-phosphatase activity" EXACT [EC:3.1.3.24] synonym: "sucrose-6F-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.24] synonym: "sucrose-phosphate hydrolase activity" EXACT [EC:3.1.3.24] synonym: "sucrose-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.24] xref: EC:3.1.3.24 xref: GO:0050307 xref: MetaCyc:SUCROSE-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007660 name: sugar-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate." [EC:3.1.3.23, MetaCyc:SUGAR-PHOSPHATASE-RXN] synonym: "sugar-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.23] xref: EC:3.1.3.23 xref: GO:0050308 xref: MetaCyc:SUGAR-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007661 name: sugar-terminal-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a sugar phosphate = a sugar + phosphate; an example is D-glucose 6-phosphate + H2O = D-glucose + phosphate." [EC:3.1.3.58, MetaCyc:SUGAR-TERMINAL-PHOSPHATASE-RXN] synonym: "sugar-omega-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.58] synonym: "xylitol-5-phosphatase activity" EXACT [EC:3.1.3.58] xref: EC:3.1.3.58 xref: GO:0050309 xref: MetaCyc:SUGAR-TERMINAL-PHOSPHATASE-RXN is_a: CCO:F0004126 ! carbohydrate phosphatase activity [Term] id: CCO:F0007662 name: sulfite dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: SO3(2-) (sulfite) + 2 ferricytochrome c + H2O = SO4(2-) (sulfate) + 2 ferrocytochrome c." [EC:1.8.2.1, MetaCyc:SULFITE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "sulfite cytochrome c reductase activity" EXACT [EC:1.8.2.1] synonym: "sulfite-cytochrome c oxidoreductase activity" EXACT [EC:1.8.2.1] synonym: "sulfite:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.8.2.1] synonym: "sulphite dehydrogenase activity" EXACT [] xref: EC:1.8.2.1 xref: GO:0050310 xref: MetaCyc:SULFITE-DEHYDROGENASE-RXN is_a: CCO:F0003262 ! oxidoreductase activity, acting on sulfur group of donors, cytochrome as acceptor [Term] id: CCO:F0007663 name: sulfite reductase (ferredoxin) activity namespace: molecular_function def: "Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = SO3(2-) (sulfite) + 3 reduced ferredoxin." [EC:1.8.7.1, MetaCyc:SULFITE-REDUCTASE-(FERREDOXIN)-RXN] subset: gosubset_prok synonym: "ferredoxin-sulfite reductase activity" EXACT [EC:1.8.7.1] synonym: "hydrogen-sulfide:ferredoxin oxidoreductase activity" EXACT [EC:1.8.7.1] synonym: "sulphite reductase (ferredoxin) activity" EXACT [] xref: EC:1.8.7.1 xref: GO:0050311 xref: MetaCyc:SULFITE-REDUCTASE-(FERREDOXIN)-RXN is_a: CCO:F0003266 ! oxidoreductase activity, acting on sulfur group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0007664 name: sulfoacetaldehyde lyase activity namespace: molecular_function def: "Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + SO3(2-) (sulfite)." [EC:4.4.1.12, MetaCyc:SULFOACETALDEHYDE-LYASE-RXN] comment: Note that EC:4.4.1.12 was deleted from EC as the reaction is performed by sulfoacetaldehyde acetyltransferase (EC:2.3.3.15). synonym: "sulphoacetaldehyde lyase activity" EXACT [] xref: EC:4.4.1.- xref: GO:0050312 xref: MetaCyc:SULFOACETALDEHYDE-LYASE-RXN is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007665 name: sulfur dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: sulfur + O2 + H2O = SO3(2-) (sulfite)." [EC:1.13.11.18, MetaCyc:SULFUR-DIOXYGENASE-RXN] synonym: "S-sulfanylglutathione:oxygen oxidoreductase activity" EXACT [EC:1.13.11.18] synonym: "sulfur oxygenase activity" EXACT [EC:1.13.11.18] synonym: "sulfur:oxygen oxidoreductase activity" EXACT [EC:1.13.11.18] synonym: "sulphur dioxygenase activity" EXACT [] xref: EC:1.13.11.18 xref: GO:0050313 xref: MetaCyc:SULFUR-DIOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007666 name: sym-norspermidine synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosylmethioninamine + propane-1,3-diamine = 5'-methylthioadenosine + bis(3-aminopropyl)amine." [EC:2.5.1.23, MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN] synonym: "S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase activity" EXACT [EC:2.5.1.23] xref: EC:2.5.1.23 xref: GO:0050314 xref: MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007667 name: synephrine dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-(methylamino)ethanol = (4-hydroxyphenyl)acetaldehyde + methylamine." [EC:4.2.1.88, MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN] synonym: "1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming)" EXACT [EC:4.2.1.88] xref: EC:4.2.1.88 xref: GO:0050315 xref: MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007668 name: T2-induced deoxynucleotide kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + dGMP (or dTMP) = ADP + dGDP (or dTDP)." [EC:2.7.4.12, MetaCyc:T2-INDUCED-DEOXYNUCLEOTIDE-KINASE-RXN] synonym: "ATP:(d)NMP phosphotransferase activity" EXACT [EC:2.7.4.12] xref: EC:2.7.4.12 xref: GO:0050316 xref: MetaCyc:GMKALT-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0007669 name: tagatose kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-tagatose = ADP + D-tagatose 6-phosphate." [EC:2.7.1.101, MetaCyc:TAGATOSE-KINASE-RXN] synonym: "ATP:D-tagatose 6-phosphotransferase activity" EXACT [EC:2.7.1.101] synonym: "D-tagatose 6-phosphate kinase activity" EXACT [EC:2.7.1.101] synonym: "tagatose 6-phosphate kinase (phosphorylating)" EXACT [EC:2.7.1.101] xref: EC:2.7.1.101 xref: GO:0050317 xref: MetaCyc:TAGATOSE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007670 name: tannase activity namespace: molecular_function def: "Catalysis of the reaction: digallate + H2O = 2 gallate." [EC:3.1.1.20, MetaCyc:TANNASE-RXN] synonym: "tannase S" RELATED [EC:3.1.1.20] synonym: "tannin acetylhydrolase activity" EXACT [EC:3.1.1.20] synonym: "tannin acylhydrolase activity" EXACT [EC:3.1.1.20] xref: EC:3.1.1.20 xref: GO:0050318 xref: MetaCyc:TANNASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007671 name: tartrate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: (R,R)-tartrate = D-glycerate + CO2." [EC:4.1.1.73, MetaCyc:TARTRATE-DECARBOXYLASE-RXN] synonym: "(R,R)-tartrate carboxy-lyase (D-glycerate-forming)" EXACT [EC:4.1.1.73] synonym: "(R,R)-tartrate carboxy-lyase activity" EXACT [EC:4.1.1.73] xref: EC:4.1.1.73 xref: GO:0050319 xref: MetaCyc:TARTRATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007672 name: tartrate epimerase activity namespace: molecular_function def: "Catalysis of the reaction: (R,R)-tartrate = meso-tartrate." [EC:5.1.2.5, MetaCyc:TARTRATE-EPIMERASE-RXN] synonym: "tartaric racemase activity" EXACT [EC:5.1.2.5] xref: EC:5.1.2.5 xref: GO:0050320 xref: MetaCyc:TARTRATE-EPIMERASE-RXN is_a: CCO:F0003419 ! racemase and epimerase activity, acting on hydroxy acids and derivatives [Term] id: CCO:F0007673 name: tau-protein kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein." [EC:2.7.11.26, MetaCyc:TAU-PROTEIN-KINASE-RXN] synonym: "[Tau protein] kinase activity" EXACT [] synonym: "ATP:tau-protein O-phosphotransferase activity" BROAD [EC:2.7.11.26] synonym: "brain protein kinase PK40erk activity" NARROW [EC:2.7.11.26] synonym: "cdk5/p20" RELATED [EC:2.7.11.26] synonym: "CDK5/p23" RELATED [EC:2.7.11.26] synonym: "glycogen synthase kinase-3beta activity" EXACT [EC:2.7.11.26] synonym: "GSK" RELATED [EC:2.7.11.26] synonym: "protein tau kinase activity" EXACT [EC:2.7.11.26] synonym: "STK31" RELATED [EC:2.7.11.26] synonym: "tau kinase activity" EXACT [EC:2.7.11.26] synonym: "tau protein kinase activity" EXACT [EC:2.7.11.26] synonym: "tau-protein kinase I activity" NARROW [EC:2.7.11.26] synonym: "tau-protein kinase II activity" NARROW [EC:2.7.11.26] synonym: "tau-tubulin kinase activity" NARROW [EC:2.7.11.26] synonym: "TPK" RELATED [EC:2.7.11.26] synonym: "TPK I" RELATED [EC:2.7.11.26] synonym: "TPK II" RELATED [EC:2.7.11.26] synonym: "TTK" RELATED [EC:2.7.11.26] xref: EC:2.7.11.26 xref: GO:0050321 xref: MetaCyc:TAU-PROTEIN-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0007674 name: taurine-2-oxoglutarate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate." [EC:2.6.1.55, MetaCyc:TAURINE-AMINOTRANSFERASE-RXN] synonym: "taurine aminotransferase activity" EXACT [] synonym: "taurine transaminase activity" EXACT [] synonym: "taurine--alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.55] synonym: "taurine--glutamate transaminase activity" EXACT [EC:2.6.1.55] synonym: "taurine:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.55] xref: EC:2.6.1.55 xref: GO:0050322 xref: MetaCyc:TAURINE-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007675 name: taurine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: taurine + H2O + acceptor = sulfoacetaldehyde + NH3 + reduced acceptor." [EC:1.4.99.2, MetaCyc:TAURINE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "taurine:(acceptor) oxidoreductase (deaminating)" EXACT [EC:1.4.99.2] synonym: "taurine:acceptor oxidoreductase (deaminating)" EXACT [EC:1.4.99.2] xref: EC:1.4.99.2 xref: GO:0050323 xref: MetaCyc:TAURINE-DEHYDROGENASE-RXN is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0007676 name: taurocyamine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + taurocyamine = ADP + N-phosphotaurocyamine." [EC:2.7.3.4, MetaCyc:TAUROCYAMINE-KINASE-RXN] synonym: "ATP:taurocyamine N-phosphotransferase activity" EXACT [EC:2.7.3.4] synonym: "ATP:taurocyamine phosphotransferase activity" EXACT [EC:2.7.3.4] synonym: "taurocyamine phosphotransferase activity" EXACT [EC:2.7.3.4] xref: EC:2.7.3.4 xref: GO:0050324 xref: MetaCyc:TAUROCYAMINE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003347 ! phosphotransferase activity, nitrogenous group as acceptor [Term] id: CCO:F0007677 name: tauropine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: tauropine + NAD+ + H2O = taurine + pyruvate + NADH." [EC:1.5.1.23, MetaCyc:TAUROPINE-DEHYDROGENASE-RXN] synonym: "2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)" EXACT [EC:1.5.1.23] synonym: "N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)" EXACT [EC:1.5.1.23] xref: EC:1.5.1.23 xref: GO:0050325 xref: MetaCyc:TAUROPINE-DEHYDROGENASE-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007678 name: taxifolin 8-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O." [EC:1.14.13.19, MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN] synonym: "taxifolin hydroxylase activity" EXACT [] synonym: "taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating)" EXACT [EC:1.14.13.19] xref: EC:1.14.13.19 xref: GO:0050326 xref: MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007679 name: testosterone 17-beta-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH." [EC:1.1.1.63, MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN] synonym: "17-beta-HSD activity" BROAD [EC:1.1.1.63] synonym: "17-ketoreductase activity" BROAD [EC:1.1.1.63] synonym: "17beta-HSD" RELATED [EC:1.1.1.63] synonym: "17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity" EXACT [EC:1.1.1.63] synonym: "testosterone 17b-dehydrogenase activity" EXACT [] synonym: "testosterone 17beta-dehydrogenase activity" EXACT [EC:1.1.1.63] xref: EC:1.1.1.63 xref: GO:0050327 xref: MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN is_a: CCO:F0005254 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007680 name: tetrahydroberberine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2." [EC:1.3.3.8, MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN] synonym: "(S)-tetrahydroberberine:oxygen oxidoreductase activity" EXACT [EC:1.3.3.8] synonym: "(S)-THB oxidase activity" EXACT [EC:1.3.3.8] synonym: "THB oxidase activity" EXACT [EC:1.3.3.8] xref: EC:1.3.3.8 xref: GO:0050328 xref: MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0007681 name: tetrahydroxypteridine cycloisomerase activity namespace: molecular_function def: "Catalysis of the reaction: tetrahydroxypteridine = xanthine-8-carboxylate." [EC:5.5.1.3, MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN] synonym: "tetrahydroxypteridine lyase (isomerizing)" EXACT [EC:5.5.1.3] xref: EC:5.5.1.3 xref: GO:0050329 xref: MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0007682 name: theanine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N5-ethyl-L-glutamine + H2O = L-glutamate + ethylamine." [EC:3.5.1.65, MetaCyc:THEANINE-HYDROLASE-RXN] synonym: "5-N-ethyl-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.65] synonym: "L-theanine amidohydrolase activity" EXACT [EC:3.5.1.65] synonym: "N5-ethyl-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.65] xref: EC:3.5.1.65 xref: GO:0050330 xref: MetaCyc:THEANINE-HYDROLASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007683 name: thiamin diphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate." [EC:2.7.4.15, MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN] synonym: "ATP:thiamin-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.15] synonym: "ATP:thiamine-diphosphate phosphotransferase activity" EXACT [EC:2.7.4.15] synonym: "protein bound thiamin diphosphate:ATP phosphoryltransferase activity" EXACT [EC:2.7.4.15] synonym: "TDP kinase activity" EXACT [EC:2.7.4.15] synonym: "thiamin diphosphate phosphotransferase activity" EXACT [EC:2.7.4.15] synonym: "thiamin pyrophosphate kinase activity" EXACT [EC:2.7.4.15] synonym: "thiamin-diphosphate kinase activity" EXACT [] synonym: "thiamine diphosphate kinase activity" EXACT [EC:2.7.4.15] synonym: "thiamine-diphosphate kinase activity" EXACT [] xref: EC:2.7.4.15 xref: GO:0050331 xref: MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0007684 name: thiamin pyridinylase activity namespace: molecular_function def: "Catalysis of the reaction: thiamin + pyridine = 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]pyridinium + 4-methyl-5-(2-hydroxyethyl)thiazole." [EC:2.5.1.2, MetaCyc:THIAMIN-PYRIDINYLASE-RXN] subset: gosubset_prok synonym: "pyrimidine transferase activity" EXACT [EC:2.5.1.2] synonym: "thiamin hydrolase activity" EXACT [EC:2.5.1.2] synonym: "thiamin pyridinolase activity" EXACT [EC:2.5.1.2] synonym: "thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity" EXACT [EC:2.5.1.2] synonym: "thiaminase I activity" NARROW [EC:2.5.1.2] synonym: "thiamine hydrolase activity" EXACT [EC:2.5.1.2] synonym: "thiamine pyridinolase activity" EXACT [EC:2.5.1.2] synonym: "thiamine pyridinylase activity" EXACT [] synonym: "thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity" EXACT [EC:2.5.1.2] xref: EC:2.5.1.2 xref: GO:0050332 xref: MetaCyc:THIAMIN-PYRIDINYLASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007685 name: thiamin-triphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: thiamin triphosphate + H2O = thiamin diphosphate + phosphate." [EC:3.6.1.28, MetaCyc:THIAMIN-TRIPHOSPHATASE-RXN] synonym: "thiamine-triphosphatase activity" EXACT [] synonym: "thiamine-triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.28] synonym: "ThTPase activity" EXACT [EC:3.6.1.28] xref: EC:3.6.1.28 xref: GO:0048253 xref: GO:0050333 xref: MetaCyc:THIAMIN-TRIPHOSPHATASE-RXN is_a: CCO:F0003574 ! nucleoside-triphosphatase activity [Term] id: CCO:F0007686 name: thiaminase activity namespace: molecular_function def: "Catalysis of the reaction: thiamin + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole." [EC:3.5.99.2, MetaCyc:THIAMINASE-RXN] synonym: "thiaminase II activity" NARROW [EC:3.5.99.2] xref: EC:3.5.99.2 xref: GO:0050334 xref: MetaCyc:THIAMINASE-RXN is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0007687 name: thiocyanate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate." [EC:5.99.1.1, MetaCyc:THIOCYANATE-ISOMERASE-RXN] synonym: "benzyl-thiocyanate isomerase activity" EXACT [EC:5.99.1.1] synonym: "isothiocyanate isomerase activity" EXACT [EC:5.99.1.1] xref: EC:5.99.1.1 xref: GO:0050335 xref: MetaCyc:THIOCYANATE-ISOMERASE-RXN is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0007688 name: thioethanolamine S-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + thioethanolamine = CoA + S-acetylthioethanolamine." [EC:2.3.1.11, MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN] synonym: "acetyl-CoA:2-aminoethanethiol S-acetyltransferase activity" EXACT [EC:2.3.1.11] synonym: "acetyl-CoA:thioethanolamine S-acetyltransferase activity" EXACT [EC:2.3.1.11] synonym: "thioethanolamine acetyltransferase activity" EXACT [EC:2.3.1.11] synonym: "thioltransacetylase B activity" EXACT [EC:2.3.1.11] xref: EC:2.3.1.11 xref: GO:0050336 xref: MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN is_a: CCO:F0003141 ! S-acetyltransferase activity [Term] id: CCO:F0007689 name: thiosulfate-thiol sulfurtransferase activity namespace: molecular_function def: "Catalysis of the reaction: thiosulfate + 2 glutathione = SO3(2-) (sulfite) + glutathione disulfide + sulfide." [EC:2.8.1.3, MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN] synonym: "glutathione-dependent thiosulfate reductase activity" EXACT [EC:2.8.1.3] synonym: "sulfane reductase activity" EXACT [EC:2.8.1.3] synonym: "sulfane sulfurtransferase activity" EXACT [EC:2.8.1.3] synonym: "thiosulfate:thiol sulfurtransferase activity" EXACT [EC:2.8.1.3] synonym: "thiosulphate-thiol sulphurtransferase activity" EXACT [] xref: EC:2.8.1.3 xref: GO:0050337 xref: MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN is_a: CCO:F0003355 ! sulfurtransferase activity [Term] id: CCO:F0007690 name: thiosulfate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c." [EC:1.8.2.2, MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN] synonym: "tetrathionate synthase activity" EXACT [EC:1.8.2.2] synonym: "thiosulfate oxidase activity" EXACT [EC:1.8.2.2] synonym: "thiosulfate-acceptor oxidoreductase activity" EXACT [EC:1.8.2.2] synonym: "thiosulfate-oxidizing enzyme" RELATED [EC:1.8.2.2] synonym: "thiosulfate:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.8.2.2] synonym: "thiosulphate dehydrogenase activity" EXACT [] xref: EC:1.8.2.2 xref: GO:0050338 xref: MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN is_a: CCO:F0003262 ! oxidoreductase activity, acting on sulfur group of donors, cytochrome as acceptor [Term] id: CCO:F0007691 name: thymidine-triphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: dTTP + H2O = dTDP + phosphate." [EC:3.6.1.39, MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN] synonym: "deoxythymidine-5'-triphosphatase activity" EXACT [EC:3.6.1.39] synonym: "dTTP nucleotidohydrolase activity" EXACT [EC:3.6.1.39] synonym: "dTTPase activity" EXACT [EC:3.6.1.39] synonym: "thymidine triphosphate nucleotidohydrolase activity" EXACT [EC:3.6.1.39] xref: EC:3.6.1.39 xref: GO:0050339 xref: MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN is_a: CCO:F0003574 ! nucleoside-triphosphatase activity [Term] id: CCO:F0007692 name: thymidylate 5'-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate." [EC:3.1.3.35, MetaCyc:THYMIDYLATE-5] synonym: "deoxythymidylate 5'-nucleotidase activity" EXACT [EC:3.1.3.35] synonym: "deoxythymidylate phosphohydrolase activity" EXACT [EC:3.1.3.35] synonym: "deoxythymidylic 5'-nucleotidase activity" EXACT [EC:3.1.3.35] synonym: "dTMPase activity" EXACT [EC:3.1.3.35] synonym: "thymidylate 5' phosphatase activity" EXACT [] synonym: "thymidylate 5'-nucleotidase activity" EXACT [EC:3.1.3.35] synonym: "thymidylate 5'-phosphohydrolase activity" EXACT [EC:3.1.3.35] synonym: "thymidylate nucleotidase activity" EXACT [EC:3.1.3.35] xref: EC:3.1.3.35 xref: GO:0050340 xref: MetaCyc:THYMIDYLATE-5 is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007693 name: thymine dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2." [EC:1.14.11.6, MetaCyc:THYMINE-DIOXYGENASE-RXN] synonym: "5-hydroxy-methyluracil dioxygenase activity" EXACT [EC:1.14.11.6] synonym: "5-hydroxymethyluracil oxygenase activity" EXACT [EC:1.14.11.6] synonym: "thymine 7-hydroxylase activity" EXACT [EC:1.14.11.6] synonym: "thymine,2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.6] synonym: "thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating)" EXACT [EC:1.14.11.6] xref: EC:1.14.11.6 xref: GO:0050341 xref: MetaCyc:THYMINE-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0007694 name: tocopherol O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol." [EC:2.1.1.95, MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN] synonym: "gamma-tocopherol methyltransferase activity" EXACT [] synonym: "S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase activity" EXACT [EC:2.1.1.95] xref: EC:2.1.1.95 xref: GO:0050342 xref: MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN is_a: CCO:F0001758 ! O-methyltransferase activity [Term] id: CCO:F0007695 name: trans-2-enoyl-CoA reductase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH." [EC:1.3.1.44, MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-(NAD+)-RXN] synonym: "acyl-CoA:NAD+ trans-2-oxidoreductase activity" EXACT [EC:1.3.1.44] xref: EC:1.3.1.44 xref: GO:0050343 xref: MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-(NAD+)-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007696 name: trans-cinnamate 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: trans-cinnamate + NADPH + O2 = 2-hydroxycinnamate + NADP+ + H2O." [EC:1.14.13.14, MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN] synonym: "cinnamate 2-hydroxylase activity" EXACT [EC:1.14.13.14] synonym: "cinnamate 2-monooxygenase activity" EXACT [EC:1.14.13.14] synonym: "cinnamic 2-hydroxylase activity" EXACT [EC:1.14.13.14] synonym: "cinnamic acid 2-hydroxylase activity" EXACT [EC:1.14.13.14] synonym: "trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)" EXACT [EC:1.14.13.14] synonym: "trans-cinnamic acid 2-hydroxylase activity" EXACT [] xref: EC:1.14.13.14 xref: GO:0050344 xref: MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007697 name: trans-epoxysuccinate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + trans-2,3-epoxysuccinate = meso-tartrate." [EC:3.3.2.4, MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN] synonym: "tartrate epoxydase activity" EXACT [EC:3.3.2.4] synonym: "trans-2,3-epoxysuccinate hydrolase activity" EXACT [EC:3.3.2.4] synonym: "trans-epoxysuccinate hydratase activity" EXACT [EC:3.3.2.4] xref: EC:3.3.2.4 xref: GO:0050345 xref: MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN is_a: CCO:F0003373 ! ether hydrolase activity [Term] id: CCO:F0007698 name: trans-L-3-hydroxyproline dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: trans-L-3-hydroxyproline = H2O + delta(1)-pyrroline_2-carboxylate." [EC:4.2.1.77, MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN] synonym: "trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline 2-carboxylate-forming)" EXACT [EC:4.2.1.77] synonym: "trans-L-3-hydroxyproline hydro-lyase activity" EXACT [EC:4.2.1.77] xref: EC:4.2.1.77 xref: GO:0050346 xref: MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007699 name: trans-octaprenyltranstransferase activity namespace: molecular_function def: "Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = diphosphate + all-trans-nonaprenyl diphosphate." [EC:2.5.1.11, MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN] synonym: "(E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase activity" EXACT [EC:2.5.1.11] synonym: "all-trans-nonaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.11] synonym: "nonaprenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.11] synonym: "polyprenylpyrophosphate synthetase activity" EXACT [EC:2.5.1.11] synonym: "solanesyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.11] synonym: "solanesyl-diphosphate synthase activity" EXACT [EC:2.5.1.11] synonym: "SPP synthase activity" EXACT [EC:2.5.1.11] synonym: "terpenoidallyltransferase activity" EXACT [EC:2.5.1.11] synonym: "terpenyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.11] synonym: "trans-prenyltransferase activity" EXACT [EC:2.5.1.11] xref: EC:2.5.1.11 xref: GO:0050347 xref: MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007700 name: trehalose O-mycolyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose + alpha,alpha'-trehalose 6,6'-bismycolate." [EC:2.3.1.122, MetaCyc:TREHALOSE-O-MYCOLYLTRANSFERASE-RXN] subset: gosubset_prok synonym: "alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase activity" EXACT [EC:2.3.1.122] synonym: "alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase activity" EXACT [EC:2.3.1.122] xref: EC:2.3.1.122 xref: GO:0050348 xref: MetaCyc:TREHALOSE-O-MYCOLYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007701 name: triacetate-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: triacetate lactone + H2O = triacetate." [EC:3.1.1.38, MetaCyc:TRIACETATE-LACTONASE-RXN] synonym: "TAL hydrolase activity" EXACT [EC:3.1.1.38] synonym: "triacetate lactone hydrolase activity" EXACT [EC:3.1.1.38] synonym: "triacetic acid lactone hydrolase activity" EXACT [EC:3.1.1.38] synonym: "triacetic lactone hydrolase activity" EXACT [EC:3.1.1.38] synonym: "triacetolactone lactonohydrolase activity" EXACT [EC:3.1.1.38] xref: EC:3.1.1.38 xref: GO:0050349 xref: MetaCyc:TRIACETATE-LACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007702 name: trihydroxystilbene synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2." [EC:2.3.1.95, MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN] synonym: "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)" BROAD [EC:2.3.1.95] synonym: "resveratrol synthase activity" EXACT [EC:2.3.1.95] synonym: "stilbene synthase activity" BROAD [EC:2.3.1.95] xref: EC:2.3.1.95 xref: GO:0050350 xref: MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007703 name: trimetaphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: trimetaphosphate + H2O = triphosphate." [EC:3.6.1.2, MetaCyc:TRIMETAPHOSPHATASE-RXN] subset: gosubset_prok synonym: "inorganic trimetaphosphatase activity" EXACT [EC:3.6.1.2] synonym: "trimetaphosphate hydrolase activity" EXACT [EC:3.6.1.2] xref: EC:3.6.1.2 xref: GO:0050351 xref: MetaCyc:TRIMETAPHOSPHATASE-RXN is_a: CCO:F0003386 ! hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Term] id: CCO:F0007704 name: trimethylamine-oxide aldolase activity namespace: molecular_function def: "Catalysis of the reaction: (CH3)3NO = (CH3)2NH + formaldehyde." [EC:4.1.2.32, MetaCyc:TRIMETHYLAMINE-OXIDE-ALDOLASE-RXN] synonym: "trimethylamine N-oxide aldolase activity" EXACT [EC:4.1.2.32] synonym: "trimethylamine N-oxide demethylase activity" EXACT [EC:4.1.2.32] synonym: "trimethylamine N-oxide formaldehyde-lyase activity" EXACT [EC:4.1.2.32] synonym: "trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)" EXACT [EC:4.1.2.32] synonym: "trimethylamine-N-oxide formaldehyde-lyase activity" EXACT [EC:4.1.2.32] xref: EC:4.1.2.32 xref: GO:0050352 xref: MetaCyc:TRIMETHYLAMINE-OXIDE-ALDOLASE-RXN xref: UM-BBD_enzymeID:e0875 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007705 name: trimethyllysine dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 = 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2." [EC:1.14.11.8, MetaCyc:TRIMETHYLLYSINE-DIOXYGENASE-RXN] synonym: "6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.8] synonym: "epsilon-trimethyllysine 2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] synonym: "N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.11.8] synonym: "TML dioxygenase activity" EXACT [EC:1.14.11.8] synonym: "TML hydroxylase activity" EXACT [EC:1.14.11.8] synonym: "TML-alpha-ketoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] synonym: "TMLD activity" EXACT [EC:1.14.11.8] synonym: "trimethyllysine alpha-ketoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] synonym: "trimethyllysine,2-oxoglutarate dioxygenase activity" EXACT [EC:1.14.11.8] xref: EC:1.14.11.8 xref: GO:0050353 xref: MetaCyc:TRIMETHYLLYSINE-DIOXYGENASE-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0007706 name: triokinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate." [EC:2.7.1.28, MetaCyc:TRIOKINASE-RXN] synonym: "ATP:D-glyceraldehyde 3-phosphotransferase activity" EXACT [EC:2.7.1.28] synonym: "D-triokinase activity" EXACT [EC:2.7.1.28] synonym: "trio triose kinase (phosphorylating)" EXACT [EC:2.7.1.28] synonym: "triose kinase activity" EXACT [EC:2.7.1.28] xref: EC:2.7.1.28 xref: GO:0050354 xref: MetaCyc:TRIOKINASE-RXN xref: Reactome:70343 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007707 name: triphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: triphosphate + H2O = diphosphate + phosphate." [EC:3.6.1.25, MetaCyc:TRIPHOSPHATASE-RXN] subset: gosubset_prok synonym: "inorganic triphosphatase activity" EXACT [EC:3.6.1.25] synonym: "triphosphate phosphohydrolase activity" EXACT [EC:3.6.1.25] xref: EC:3.6.1.25 xref: GO:0050355 xref: MetaCyc:TRIPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0007708 name: tropine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: tropine + NADP+ = tropinone + NADPH." [EC:1.1.1.206, MetaCyc:TROPINE-DEHYDROGENASE-RXN] synonym: "tropine:NADP+ 3alpha-oxidoreductase activity" EXACT [EC:1.1.1.206] xref: EC:1.1.1.206 xref: GO:0050356 xref: MetaCyc:TROPINE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007709 name: tropinesterase activity namespace: molecular_function def: "Catalysis of the reaction: atropine + H2O = tropine + tropate." [EC:3.1.1.10, MetaCyc:TROPINESTERASE-RXN] subset: gosubset_prok synonym: "atropinase activity" EXACT [EC:3.1.1.10] synonym: "atropine acylhydrolase activity" EXACT [EC:3.1.1.10] synonym: "atropine esterase activity" EXACT [EC:3.1.1.10] synonym: "atropinesterase activity" EXACT [EC:3.1.1.10] synonym: "tropine esterase activity" EXACT [EC:3.1.1.10] xref: EC:3.1.1.10 xref: GO:0050357 xref: MetaCyc:TROPINESTERASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007710 name: tropinone reductase activity namespace: molecular_function def: "Catalysis of the reaction: pseudotropine + NADP+ = tropinone + NADPH." [EC:1.1.1.236, MetaCyc:TROPINONE-REDUCTASE-RXN] synonym: "pseudotropine forming tropinone reductase activity" EXACT [EC:1.1.1.236] synonym: "pseudotropine:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.236] synonym: "tropinone (psi-tropine-forming) reductase activity" EXACT [EC:1.1.1.236] synonym: "tropinone reductase II activity" RELATED [EC:1.1.1.236] xref: EC:1.1.1.236 xref: GO:0050358 xref: MetaCyc:TROPINONE-REDUCTASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007711 name: tropomyosin kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin." [EC:2.7.11.28, MetaCyc:TROPOMYOSIN-KINASE-RXN] synonym: "ATP:tropomyosin O-phosphotransferase activity" EXACT [EC:2.7.11.28] synonym: "STK" RELATED [EC:2.7.11.28] synonym: "tropomyosin kinase (phosphorylating) activity" EXACT [EC:2.7.11.28] xref: EC:2.7.11.28 xref: GO:0050359 xref: MetaCyc:TROPOMYOSIN-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0007712 name: tryptophan 2'-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3." [EC:1.13.99.3, MetaCyc:TRYPTOPHAN-2] synonym: "indole-3-alkane alpha-hydroxylase activity" EXACT [EC:1.13.99.3] synonym: "indolyl-3-alkan alpha-hydroxylase activity" EXACT [EC:1.13.99.3] synonym: "L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving)" EXACT [EC:1.13.99.3] synonym: "tryptophan side chain oxidase activity" EXACT [EC:1.13.99.3] synonym: "tryptophan side chain oxidase II" RELATED [EC:1.13.99.3] synonym: "tryptophan side chain oxidase type I" RELATED [EC:1.13.99.3] synonym: "tryptophan side-chain alpha,beta-oxidase activity" RELATED [EC:1.13.99.3] synonym: "tryptophan side-chain oxidase activity" RELATED [EC:1.13.99.3] synonym: "TSO activity" RELATED [EC:1.13.99.3] synonym: "TSO I" RELATED [EC:1.13.99.3] synonym: "TSO II" RELATED [EC:1.13.99.3] xref: EC:1.13.99.3 xref: GO:0050360 xref: MetaCyc:TRYPTOPHAN-2 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Term] id: CCO:F0007713 name: tryptophan 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + O2 = indole-3-acetamide + CO2 + H2O." [EC:1.13.12.3, MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN] subset: gosubset_prok synonym: "L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.3] xref: EC:1.13.12.3 xref: GO:0050361 xref: MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) [Term] id: CCO:F0007714 name: tryptophan transaminase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate." [EC:2.6.1.27, MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN] synonym: "5-hydroxytryptophan-ketoglutaric transaminase activity" EXACT [EC:2.6.1.27] synonym: "hydroxytryptophan aminotransferase activity" EXACT [EC:2.6.1.27] synonym: "L-phenylalanine-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.27] synonym: "L-tryptophan aminotransferase activity" EXACT [EC:2.6.1.27] synonym: "L-tryptophan transaminase activity" EXACT [EC:2.6.1.27] synonym: "L-tryptophan:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.27] synonym: "tryptophan aminotransferase activity" EXACT [] xref: EC:2.6.1.27 xref: GO:0050362 xref: MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0007715 name: tryptophan dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+." [EC:1.4.1.19, MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN] synonym: "L-Trp-dehydrogenase activity" EXACT [EC:1.4.1.19] synonym: "L-tryptophan dehydrogenase activity" EXACT [EC:1.4.1.19] synonym: "L-tryptophan:NAD(P)+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.19] synonym: "NAD(P)+-L-tryptophan dehydrogenase activity" EXACT [EC:1.4.1.19] synonym: "TDH" RELATED [EC:1.4.1.19] synonym: "TrpDH activity" EXACT [EC:1.4.1.19] xref: EC:1.4.1.19 xref: GO:0050363 xref: MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007716 name: tryptophan dimethylallyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan." [EC:2.5.1.34, MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN] synonym: "4-(gamma,gamma-dimethylallyl)tryptophan synthase activity" EXACT [EC:2.5.1.34] synonym: "dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase activity" EXACT [EC:2.5.1.34] synonym: "dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase activity" EXACT [EC:2.5.1.34] synonym: "dimethylallylpyrophosphate:tryptophan dimethylallyl transferase activity" EXACT [EC:2.5.1.34] synonym: "dimethylallyltryptophan synthetase activity" EXACT [EC:2.5.1.34] synonym: "DMAT synthetase activity" EXACT [EC:2.5.1.34] xref: EC:2.5.1.34 xref: GO:0050364 xref: MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007717 name: tryptophanamidase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophanamide + H2O = L-tryptophan + NH3." [EC:3.5.1.57, MetaCyc:TRYPTOPHANAMIDASE-RXN] synonym: "L-tryptophan aminopeptidase" BROAD [EC:3.5.1.57] synonym: "L-tryptophanamide amidohydrolase activity" EXACT [EC:3.5.1.57] synonym: "tryptophan aminopeptidase" BROAD [EC:3.5.1.57] xref: EC:3.5.1.57 xref: GO:0050365 xref: MetaCyc:TRYPTOPHANAMIDASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007718 name: tyramine N-feruloyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine." [EC:2.3.1.110, MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN] synonym: "feruloyl-CoA tyramine N-feruloyl-CoA transferase activity" EXACT [EC:2.3.1.110] synonym: "feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase activity" EXACT [EC:2.3.1.110] synonym: "feruloyltyramine synthase activity" EXACT [EC:2.3.1.110] synonym: "tyramine feruloyltransferase activity" EXACT [EC:2.3.1.110] synonym: "tyramine N-feruloyl-CoA transferase activity" EXACT [EC:2.3.1.110] xref: EC:2.3.1.110 xref: GO:0050366 xref: MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007719 name: tyrosine-arginine ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-tyrosine + L-arginine = AMP + diphosphate + L-tyrosyl-L-arginine." [EC:6.3.2.24, MetaCyc:TYROSINE--ARGININE-LIGASE-RXN] synonym: "kyotorphin synthase activity" EXACT [EC:6.3.2.24] synonym: "kyotorphin synthetase activity" EXACT [EC:6.3.2.24] synonym: "kyotorphin-synthesizing enzyme activity" EXACT [EC:6.3.2.24] synonym: "L-tyrosine:L-arginine ligase (AMP-forming)" EXACT [EC:6.3.2.24] synonym: "tyrosyl-arginine synthase activity" EXACT [EC:6.3.2.24] xref: EC:6.3.2.24 xref: GO:0050367 xref: MetaCyc:TYROSINE--ARGININE-LIGASE-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0007720 name: tyrosine 2,3-aminomutase activity namespace: molecular_function def: "Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate." [EC:5.4.3.6, MetaCyc:TYROSINE-2] synonym: "L-tyrosine 2,3-aminomutase activity" EXACT [EC:5.4.3.6] synonym: "tyrosine alpha,beta-mutase activity" EXACT [EC:5.4.3.6] xref: EC:5.4.3.6 xref: GO:0050368 xref: MetaCyc:TYROSINE-2 is_a: CCO:F0003430 ! intramolecular transferase activity, transferring amino groups [Term] id: CCO:F0007722 name: tyrosine N-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O." [EC:1.14.13.41, MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN] synonym: "CYP79A1 activity" NARROW [EC:1.14.13.41] synonym: "L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)" EXACT [EC:1.14.13.41] synonym: "tyrosine N-hydroxylase activity" EXACT [] xref: EC:1.14.13.41 xref: GO:0050370 xref: MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007723 name: tyrosine phenol-lyase activity namespace: molecular_function def: "Catalysis of the reaction: L-tyrosine + H2O = phenol + pyruvate + NH3." [EC:4.1.99.2, MetaCyc:TYROSINE-PHENOL-LYASE-RXN] subset: gosubset_prok synonym: "beta-tyrosinase activity" EXACT [EC:4.1.99.2] synonym: "L-tyrosine phenol-lyase (deaminating)" EXACT [EC:4.1.99.2] synonym: "L-tyrosine phenol-lyase (deaminating; pyruvate-forming)" EXACT [EC:4.1.99.2] xref: EC:4.1.99.2 xref: GO:0050371 xref: MetaCyc:TYROSINE-PHENOL-LYASE-RXN is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0007724 name: ubiquitin-calmodulin ligase activity namespace: molecular_function def: "Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin." [EC:6.3.2.21, MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN] synonym: "calmodulin:ubiquitin ligase (AMP-forming)" EXACT [EC:6.3.2.21] synonym: "ubiquitin-calmodulin synthetase activity" EXACT [EC:6.3.2.21] synonym: "ubiquityl-calmodulin synthase activity" EXACT [EC:6.3.2.21] synonym: "ubiquityl-calmodulin synthetase activity" EXACT [EC:6.3.2.21] synonym: "uCaM-synthetase activity" EXACT [EC:6.3.2.21] xref: EC:6.3.2.21 xref: GO:0050372 xref: MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN is_a: CCO:F0001198 ! ubiquitin-protein ligase activity [Term] id: CCO:F0007725 name: UDP-arabinose 4-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-L-arabinose = UDP-D-xylose." [EC:5.1.3.5, MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN] synonym: "UDP arabinose epimerase activity" EXACT [EC:5.1.3.5] synonym: "UDP-D-xylose 4-epimerase activity" EXACT [EC:5.1.3.5] synonym: "UDP-D-xylose-4-epimerase activity" EXACT [] synonym: "UDP-L-arabinose 4-epimerase activity" EXACT [EC:5.1.3.5] synonym: "UDParabinose 4-epimerase activity" EXACT [EC:5.1.3.5] synonym: "uridine 5'-diphosphate-D-xylose 4-epimerase activity" EXACT [EC:5.1.3.5] synonym: "uridine diphosphoarabinose epimerase activity" EXACT [EC:5.1.3.5] xref: EC:5.1.3.5 xref: GO:0050373 xref: MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007726 name: UDP-galacturonate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-D-galacturonate = UDP-L-arabinose + CO2." [EC:4.1.1.67, MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN] synonym: "UDP-D-galacturonate carboxy-lyase (UDP-L-arabinose-forming)" EXACT [EC:4.1.1.67] synonym: "UDP-D-galacturonate carboxy-lyase activity" EXACT [EC:4.1.1.67] synonym: "UDP-galacturonic acid decarboxylase activity" EXACT [EC:4.1.1.67] synonym: "UDPgalacturonate decarboxylase activity" EXACT [EC:4.1.1.67] synonym: "UDPGalUA carboxy lyase activity" EXACT [EC:4.1.1.67] xref: EC:4.1.1.67 xref: GO:0050374 xref: MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007727 name: UDP-glucosamine 4-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucosamine = UDPgalactosamine." [EC:5.1.3.16, MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN] synonym: "UDP-glucosamine epimerase activity" EXACT [] synonym: "UDPglucosamine 4-epimerase activity" EXACT [EC:5.1.3.16] xref: EC:5.1.3.16 xref: GO:0050376 xref: MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007728 name: UDP-glucose 4,6-dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose = UDP-4-dehydro-6-deoxy-D-glucose + H2O." [EC:4.2.1.76, MetaCyc:UDP-GLUCOSE-4] synonym: "UDP-D-glucose oxidoreductase activity" EXACT [EC:4.2.1.76] synonym: "UDP-D-glucose-4,6-hydrolyase activity" EXACT [EC:4.2.1.76] synonym: "UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)" EXACT [EC:4.2.1.76] synonym: "UDP-glucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.76] synonym: "UDPglucose 4,6-dehydratase activity" EXACT [EC:4.2.1.76] synonym: "UDPglucose 4,6-hydro-lyase activity" EXACT [EC:4.2.1.76] xref: EC:4.2.1.76 xref: GO:0050377 xref: MetaCyc:UDP-GLUCOSE-4 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007729 name: UDP-glucuronate 4-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucuronate = UDP-D-galacturonate." [EC:5.1.3.6, MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN] synonym: "UDP glucuronic epimerase activity" EXACT [EC:5.1.3.6] synonym: "UDP-D-galacturonic acid 4-epimerase activity" EXACT [EC:5.1.3.6] synonym: "UDP-galacturonate 4-epimerase activity" EXACT [EC:5.1.3.6] synonym: "UDPglucuronate 4-epimerase activity" EXACT [EC:5.1.3.6] synonym: "uridine diphospho-D-galacturonic acid" RELATED [EC:5.1.3.6] synonym: "uridine diphosphoglucuronate epimerase activity" EXACT [EC:5.1.3.6] synonym: "uridine diphosphoglucuronic epimerase activity" EXACT [EC:5.1.3.6] xref: EC:5.1.3.6 xref: GO:0050378 xref: MetaCyc:PWY-4861 xref: MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007730 name: UDP-glucuronate 5'-epimerase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucuronate = UDP-L-iduronate." [EC:5.1.3.12, MetaCyc:UDP-GLUCURONATE-5] subset: gosubset_prok synonym: "C-5-uronosyl epimerase activity" EXACT [EC:5.1.3.12] synonym: "UDP-glucuronate 5' epimerase activity" EXACT [] synonym: "UDP-glucuronic acid 5'-epimerase activity" EXACT [EC:5.1.3.12] synonym: "UDP-glucuronic acid epimerase activity" EXACT [EC:5.1.3.12] synonym: "UDPglucuronate 5'-epimerase activity" EXACT [EC:5.1.3.12] synonym: "uridine diphosphoglucuronate 5'-epimerase activity" EXACT [EC:5.1.3.12] xref: EC:5.1.3.12 xref: GO:0050379 xref: MetaCyc:UDP-GLUCURONATE-5 is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007731 name: undecaprenyl-diphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate." [EC:3.6.1.27, MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN] subset: gosubset_prok synonym: "C(55)-isoprenyl diphosphatase activity" EXACT [EC:3.6.1.27] synonym: "C(55)-isoprenyl pyrophosphatase activity" EXACT [EC:3.6.1.27] synonym: "C55-isoprenyl diphosphatase activity" EXACT [EC:3.6.1.27] synonym: "C55-isoprenyl pyrophosphatase activity" EXACT [EC:3.6.1.27] synonym: "isoprenyl pyrophosphatase activity" EXACT [EC:3.6.1.27] synonym: "undecaprenyl-diphosphate phosphohydrolase activity" EXACT [EC:3.6.1.27] xref: EC:3.6.1.27 xref: GO:0050380 xref: MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0007732 name: unspecific monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O." [EC:1.14.14.1] subset: gosubset_prok synonym: "aromatase activity" EXACT [] synonym: "aryl hydrocarbon hydroxylase activity" EXACT [EC:1.14.14.1] synonym: "aryl-4-monooxygenase activity" EXACT [EC:1.14.14.1] synonym: "cytochrome p450 activity" NARROW [EC:1.14.14.1] synonym: "cytochrome P450 CYP19" NARROW [] synonym: "estrogen synthetase activity" NARROW [] synonym: "flavoprotein monooxygenase activity" EXACT [EC:1.14.14.1] synonym: "flavoprotein-linked monooxygenase activity" EXACT [EC:1.14.14.1] synonym: "microsomal monooxygenase activity" NARROW [EC:1.14.14.1] synonym: "microsomal P-450" RELATED [EC:1.14.14.1] synonym: "microsomal p450 activity" NARROW [EC:1.14.14.1] synonym: "substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)" EXACT [EC:1.14.14.1] synonym: "xenobiotic monooxygenase activity" RELATED [EC:1.14.14.1] xref: EC:1.14.14.1 xref: GO:0008402 xref: GO:0050381 xref: MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0551 is_a: CCO:F0003295 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007733 name: uracil-5-carboxylate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: uracil 5-carboxylate = uracil + CO2." [EC:4.1.1.66, MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN] synonym: "uracil-5-carboxylate carboxy-lyase (uracil-forming)" EXACT [EC:4.1.1.66] synonym: "uracil-5-carboxylate carboxy-lyase activity" EXACT [EC:4.1.1.66] synonym: "uracil-5-carboxylic acid decarboxylase activity" EXACT [EC:4.1.1.66] xref: EC:4.1.1.66 xref: GO:0050382 xref: MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007734 name: uracil dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor." [EC:1.1.99.19, MetaCyc:URACIL-DEHYDROGENASE-RXN] xref: EC:1.1.99.19 xref: GO:0050383 xref: MetaCyc:URACIL-DEHYDROGENASE-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0007735 name: urate-ribonucleotide phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: urate D-ribonucleotide + phosphate = urate + D-ribose 1-phosphate." [EC:2.4.2.16, MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN] synonym: "UAR phosphorylase activity" EXACT [EC:2.4.2.16] synonym: "urate-ribonucleotide:phosphate alpha-D-ribosyltransferase activity" EXACT [EC:2.4.2.16] synonym: "urate-ribonucleotide:phosphate D-ribosyltransferase activity" EXACT [EC:2.4.2.16] xref: EC:2.4.2.16 xref: GO:0050384 xref: MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0007736 name: ureidoglycolate lyase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-ureidoglycolate = glyoxylate + urea." [EC:4.3.2.3, MetaCyc:UREIDOGLYCOLATE-LYASE-RXN] synonym: "(S)-ureidoglycolate urea-lyase (glyoxylate-forming)" EXACT [EC:4.3.2.3] synonym: "(S)-ureidoglycolate urea-lyase activity" EXACT [EC:4.3.2.3] synonym: "ureidoglycolase activity" RELATED [EC:4.3.2.3] synonym: "ureidoglycolatase activity" RELATED [EC:4.3.2.3] xref: EC:4.3.2.3 xref: GO:0050385 xref: MetaCyc:UREIDOGLYCOLATE-LYASE-RXN is_a: CCO:F0003407 ! amidine-lyase activity [Term] id: CCO:F0007737 name: ureidosuccinase activity namespace: molecular_function def: "Catalysis of the reaction: N-carbamoyl-L-aspartate + H2O = L-aspartate + CO2 + NH3." [EC:3.5.1.7, MetaCyc:UREIDOSUCCINASE-RXN] synonym: "N-carbamoyl-L-aspartate amidohydrolase activity" EXACT [EC:3.5.1.7] xref: EC:3.5.1.7 xref: GO:0050386 xref: MetaCyc:UREIDOSUCCINASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007738 name: urethanase activity namespace: molecular_function def: "Catalysis of the reaction: urethane + H2O = ethanol + CO2 + NH3." [EC:3.5.1.75, MetaCyc:URETHANASE-RXN] synonym: "urethane amidohydrolase (decarboxylating)" EXACT [EC:3.5.1.75] synonym: "urethane hydrolase activity" EXACT [EC:3.5.1.75] xref: EC:3.5.1.75 xref: GO:0050387 xref: MetaCyc:URETHANASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007739 name: uronate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: D-galacturonate + NAD+ + H2O = D-galactarate + NADH." [EC:1.1.1.203, MetaCyc:URONATE-DEHYDROGENASE-RXN] synonym: "uronate: NAD-oxidoreductase activity" EXACT [EC:1.1.1.203] synonym: "uronate:NAD+ 1-oxidoreductase activity" EXACT [EC:1.1.1.203] synonym: "uronic acid dehydrogenase activity" EXACT [EC:1.1.1.203] xref: EC:1.1.1.203 xref: GO:0050388 xref: MetaCyc:URONATE-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007740 name: uronolactonase activity namespace: molecular_function def: "Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate." [EC:3.1.1.19, MetaCyc:URONOLACTONASE-RXN] synonym: "D-glucurono-6,2-lactone lactonohydrolase activity" EXACT [EC:3.1.1.19] synonym: "glucuronolactonase activity" EXACT [EC:3.1.1.19] xref: EC:3.1.1.19 xref: GO:0050389 xref: MetaCyc:URONOLACTONASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007741 name: valine decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: L-valine = 2-methylpropanamine + CO2." [EC:4.1.1.14, MetaCyc:VALINE-DECARBOXYLASE-RXN] synonym: "L-valine carboxy-lyase (2-methylpropanamine-forming)" EXACT [EC:4.1.1.14] synonym: "L-valine carboxy-lyase activity" EXACT [EC:4.1.1.14] synonym: "l-valine carboxy-lyase activity" EXACT [EC:4.1.1.14] synonym: "leucine decarboxylase activity" EXACT [EC:4.1.1.14] xref: EC:4.1.1.14 xref: GO:0050390 xref: MetaCyc:VALINE-DECARBOXYLASE-RXN xref: UM-BBD_enzymeID:e0655 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007742 name: valine dehydrogenase (NADP) activity namespace: molecular_function def: "Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH." [EC:1.4.1.8, MetaCyc:VALINE-DEHYDROGENASE-(NADP+)-RXN] synonym: "L-valine:NADP+ oxidoreductase (deaminating)" EXACT [EC:1.4.1.8] synonym: "valine dehydrogenase (NADP+) activity" EXACT [] synonym: "valine dehydrogenase (nicotinanide adenine dinucleotide phosphate)" EXACT [EC:1.4.1.8] xref: EC:1.4.1.8 xref: GO:0050391 xref: MetaCyc:VALINE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003239 ! oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007743 name: vicianin beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-vicianin + H2O = mandelonitrile + vicianose." [EC:3.2.1.119, MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN] synonym: "(R)-vicianin beta-D-glucohydrolase activity" EXACT [EC:3.2.1.119] synonym: "vicianin b-glucosidase activity" EXACT [] synonym: "vicianin hydrolase activity" EXACT [EC:3.2.1.119] xref: EC:3.2.1.119 xref: GO:0050392 xref: MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007744 name: vinylacetyl-CoA delta-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: vinylacetyl-CoA = crotonyl-CoA." [EC:5.3.3.3, MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN] subset: gosubset_prok synonym: "delta3-cis-delta2-trans-enoyl-CoA isomerase" BROAD [EC:5.3.3.3] synonym: "vinylacetyl coenzyme A delta-isomerase activity" EXACT [EC:5.3.3.3] synonym: "vinylacetyl coenzyme A isomerase activity" EXACT [EC:5.3.3.3] synonym: "vinylacetyl-CoA D-isomerase activity" EXACT [] synonym: "vinylacetyl-CoA delta3-delta2-isomerase activity" EXACT [EC:5.3.3.3] xref: EC:5.3.3.3 xref: GO:0050393 xref: MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0007745 name: viomycin kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin." [EC:2.7.1.103, MetaCyc:VIOMYCIN-KINASE-RXN] subset: gosubset_prok synonym: "ATP:viomycin O-phosphotransferase activity" EXACT [EC:2.7.1.103] synonym: "capreomycin phosphotransferase activity" EXACT [EC:2.7.1.103] synonym: "viomycin phosphotransferase activity" EXACT [EC:2.7.1.103] xref: EC:2.7.1.103 xref: GO:0050394 xref: MetaCyc:VIOMYCIN-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007746 name: vitexin beta-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: vitexin + UDP-D-glucose = vitexin 2'-O-beta-D-glucoside + UDP." [EC:2.4.1.105, MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN] synonym: "UDP-glucose:vitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.105] synonym: "UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.105] synonym: "uridine diphosphoglucose-vitexin 2''-glucosyltransferase activity" EXACT [EC:2.4.1.105] synonym: "vitexin b-glucosyltransferase activity" EXACT [] xref: EC:2.4.1.105 xref: GO:0050395 xref: MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007747 name: vomifoliol 4'-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + (+-)-6-hydroxy-3-oxo-alpha-ionol = NADH + (+-)-6-hydroxy-3-oxo-alpha-ionone." [EC:1.1.1.221, MetaCyc:VOMIFOLIOL-4] synonym: "vomifoliol:NAD+ 4'-oxidoreductase activity" EXACT [EC:1.1.1.221] xref: EC:1.1.1.221 xref: GO:0050396 xref: MetaCyc:VOMIFOLIOL-4 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007748 name: Watasenia-luciferin 2-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light." [EC:1.13.12.8, MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN] synonym: "luciferase activity" BROAD [EC:1.13.12.8] synonym: "Watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating)" EXACT [EC:1.13.12.8] synonym: "Watasenia-type luciferase activity" EXACT [EC:1.13.12.8] synonym: "watasenia-type luciferase activity" EXACT [EC:1.13.12.8] xref: EC:1.13.12.8 xref: GO:0050397 xref: MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) is_a: CCO:F0006100 ! luciferin monooxygenase activity [Term] id: CCO:F0007749 name: wax-ester hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate." [EC:3.1.1.50, MetaCyc:WAX-ESTER-HYDROLASE-RXN] synonym: "jojoba wax esterase" NARROW [EC:3.1.1.50] synonym: "wax-ester acylhydrolase activity" EXACT [EC:3.1.1.50] synonym: "WEH" RELATED [EC:3.1.1.50] xref: EC:3.1.1.50 xref: GO:0050398 xref: MetaCyc:WAX-ESTER-HYDROLASE-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007750 name: xanthommatin reductase activity namespace: molecular_function def: "Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD+ = xanthommatin + NADH." [EC:1.3.1.41, MetaCyc:XANTHOMMATIN-REDUCTASE-RXN] synonym: "5,12-dihydroxanthommatin:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.41] xref: EC:1.3.1.41 xref: GO:0050399 xref: MetaCyc:XANTHOMMATIN-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007751 name: xylitol kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + xylitol = ADP + xylitol 5-phosphate." [EC:2.7.1.122, MetaCyc:XYLITOL-KINASE-RXN] synonym: "ATP:xylitol 5-phosphotransferase activity" EXACT [EC:2.7.1.122] synonym: "xylitol phosphotransferase activity" EXACT [EC:2.7.1.122] xref: EC:2.7.1.122 xref: GO:0050400 xref: MetaCyc:XYLITOL-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007752 name: xylonate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-xylonate + H2O." [EC:4.2.1.82, MetaCyc:XYLONATE-DEHYDRATASE-RXN] synonym: "D-xylo-aldonate dehydratase activity" EXACT [EC:4.2.1.82] synonym: "D-xylonate dehydratase activity" EXACT [EC:4.2.1.82] synonym: "D-xylonate hydro-lyase (2-dehydro-3-deoxy-D-xylonate-forming)" EXACT [EC:4.2.1.82] synonym: "D-xylonate hydro-lyase activity" EXACT [EC:4.2.1.82] xref: EC:4.2.1.82 xref: GO:0050401 xref: MetaCyc:XYLONATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007753 name: xylono-1,4-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate." [EC:3.1.1.68, MetaCyc:XYLONO-1] synonym: "D-xylono-1,4-lactone lactonohydrolase activity" EXACT [EC:3.1.1.68] synonym: "xylono-g-lactonase activity" EXACT [EC:3.1.1.68] synonym: "xylonolactonase activity" EXACT [EC:3.1.1.68] xref: EC:3.1.1.68 xref: GO:0050402 xref: MetaCyc:XYLONO-1 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007754 name: trans-zeatin O-beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + trans-zeatin = UDP + O-beta-D-glucosyl-trans-zeatin." [EC:2.4.1.203, MetaCyc:ZEATIN-O-BETA-D-GLUCOSYLTRANSFERASE-RXN] synonym: "UDP-glucose:trans-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.203] synonym: "UDPglucose:trans-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.203] synonym: "uridine diphosphoglucose-zeatin O-glucosyltransferase activity" EXACT [EC:2.4.1.203] synonym: "zeatin O-b-D-glucosyltransferase activity" EXACT [] synonym: "zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.203] synonym: "zeatin O-glucosyltransferase activity" EXACT [EC:2.4.1.203] xref: EC:2.4.1.203 xref: GO:0050403 xref: MetaCyc:RXN-4723 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007755 name: zeatin O-beta-D-xylosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-D-xylose + zeatin = UDP + O-beta-D-xylosylzeatin." [EC:2.4.1.204, MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN] comment: Note that this function was formerly EC:2.4.1.204. synonym: "UDP-D-xylose:zeatin O-beta-D-xylosyltransferase activity" EXACT [EC:2.4.2.40] synonym: "uridine diphosphoxylose-zeatin xylosyltransferase activity" EXACT [EC:2.4.2.40] synonym: "zeatin O-b-D-xylosyltransferase activity" EXACT [] synonym: "zeatin O-xylosyltransferase activity" EXACT [EC:2.4.2.40] xref: EC:2.4.2.40 xref: GO:0050404 xref: MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN is_a: CCO:F0005581 ! UDP-xylosyltransferase activity [Term] id: CCO:F0007760 name: indolylacetylinositol arabinosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-L-arabinose + indol-3-ylacetyl-myo-inositol = UDP + indol-3-ylacetyl-myo-inositol L-arabinoside." [EC:2.4.2.34, MetaCyc:2.4.2.34-RXN] subset: gosubset_prok synonym: "arabinosylindolylacetylinositol synthase activity" EXACT [EC:2.4.2.34] synonym: "UDP-L-arabinose:(indol-3-yl)acetyl-myo-inositol L-arabinosyltransferase activity" EXACT [EC:2.4.2.34] synonym: "UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase activity" EXACT [EC:2.4.2.34] xref: EC:2.4.2.34 xref: GO:0050409 xref: MetaCyc:2.4.2.34-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003338 ! transferase activity, transferring pentosyl groups [Term] id: CCO:F0007761 name: 3-oxolaurate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-oxododecanoate = 2-undecanone + CO2." [EC:4.1.1.56, MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN] synonym: "3-oxododecanoate carboxy-lyase (2-undecanone-forming)" EXACT [EC:4.1.1.56] synonym: "3-oxododecanoate carboxy-lyase activity" EXACT [EC:4.1.1.56] synonym: "beta-ketoacyl decarboxylase activity" EXACT [EC:4.1.1.56] synonym: "beta-ketolaurate decarboxylase activity" EXACT [EC:4.1.1.56] xref: EC:4.1.1.56 xref: GO:0050410 xref: MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007762 name: agaritine gamma-glutamyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor." [EC:2.3.2.9, MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN] synonym: "(gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity" EXACT [EC:2.3.2.9] synonym: "(gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity" EXACT [EC:2.3.2.9] synonym: "agaritine g-glutamyltransferase activity" EXACT [] xref: EC:2.3.2.9 xref: GO:0050411 xref: MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN is_a: CCO:F0003330 ! transferase activity, transferring amino-acyl groups [Term] id: CCO:F0007763 name: cinnamate beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + trans-cinnamate = UDP + trans-cinnamoyl beta-D-glucoside." [EC:2.4.1.177, MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN] synonym: "cinnamate b-D-glucosyltransferase activity" EXACT [] synonym: "cinnamate glucosyltransferase activity" EXACT [] synonym: "UDP-glucose:trans-cinnamate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.177] synonym: "UDPG:t-cinnamate glucosyltransferase activity" EXACT [EC:2.4.1.177] synonym: "UDPglucose:trans-cinnamate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.177] synonym: "uridine diphosphoglucose-cinnamate glucosyltransferase activity" EXACT [EC:2.4.1.177] xref: EC:2.4.1.177 xref: GO:0050412 xref: MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007764 name: D-alanine 2-hydroxymethyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H2O = tetrahydrofolate + 2-methylserine." [EC:2.1.2.7, MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN] synonym: "2-methylserine hydroxymethyltransferase activity" EXACT [EC:2.1.2.7] synonym: "5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase activity" EXACT [EC:2.1.2.7] synonym: "D-alanine hydroxymethyltransferase activity" EXACT [] xref: EC:2.1.2.7 xref: GO:0050413 xref: MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN is_a: CCO:F0003318 ! hydroxymethyl-, formyl- and related transferase activity [Term] id: CCO:F0007765 name: formimidoylaspartate deiminase activity namespace: molecular_function def: "Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3." [EC:3.5.3.5, MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN] synonym: "formiminoaspartate deiminase activity" EXACT [] synonym: "N-formimidoyl-L-aspartate iminohydrolase activity" EXACT [EC:3.5.3.5] xref: EC:3.5.3.5 xref: GO:0050414 xref: MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007766 name: formimidoylglutamase activity namespace: molecular_function def: "Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = L-glutamate + formamide." [EC:3.5.3.8, MetaCyc:FORMIMINOGLUTAMASE-RXN] subset: gosubset_prok synonym: "formiminoglutamase activity" EXACT [] synonym: "formiminoglutamate hydrolase activity" EXACT [EC:3.5.3.8] synonym: "N-formimidoyl-L-glutamate formimidoylhydrolase activity" EXACT [EC:3.5.3.8] synonym: "N-formimino-L-glutamate formiminohydrolase activity" EXACT [EC:3.5.3.8] synonym: "N-formiminoglutamate hydrolase activity" EXACT [EC:3.5.3.8] xref: EC:3.5.3.8 xref: GO:0050415 xref: MetaCyc:FORMIMINOGLUTAMASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007767 name: formimidoylglutamate deiminase activity namespace: molecular_function def: "Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3." [EC:3.5.3.13, MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN] subset: gosubset_prok synonym: "formiminoglutamate deiminase activity" EXACT [] synonym: "formiminoglutamic iminohydrolase activity" EXACT [EC:3.5.3.13] synonym: "N-formimidoyl-L-glutamate iminohydrolase activity" EXACT [EC:3.5.3.13] xref: EC:3.5.3.13 xref: GO:0050416 xref: MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0007768 name: glutamin-(asparagin-)ase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + L-glutamine (or L-asparagine) = NH3 + L-glutamate (or L-aspartate)." [EC:3.5.1.38, MetaCyc:GLUTAMINASE-(ASPARAGIN-)ASE-RXN] subset: gosubset_prok synonym: "glutaminase-(asparagin-)ase activity" EXACT [] synonym: "glutaminase-asparaginase activity" EXACT [EC:3.5.1.38] synonym: "L-ASNase/L-GLNase activity" EXACT [EC:3.5.1.38] synonym: "L-asparagine/L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.38] synonym: "L-glutamine(L-asparagine) amidohydrolase activity" EXACT [EC:3.5.1.38] xref: EC:3.5.1.38 xref: GO:0050417 xref: MetaCyc:GLUTAMINASE-(ASPARAGIN-)ASE-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007769 name: hydroxylamine reductase activity namespace: molecular_function def: "Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor." [EC:1.7.99.1, MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN] subset: gosubset_prok synonym: "ammonia:(acceptor) oxidoreductase activity" EXACT [EC:1.7.99.1] synonym: "ammonia:acceptor oxidoreductase activity" EXACT [EC:1.7.99.1] synonym: "hydroxylamine (acceptor) reductase activity" EXACT [EC:1.7.99.1] xref: EC:1.7.99.1 xref: GO:0050418 xref: MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN is_a: CCO:F0003256 ! oxidoreductase activity, acting on other nitrogenous compounds as donors [Term] id: CCO:F0007770 name: hydroxymandelonitrile lyase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate." [EC:4.1.2.11, MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN] synonym: "(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)" EXACT [EC:4.1.2.11] synonym: "(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase activity" EXACT [EC:4.1.2.11] synonym: "hydroxynitrile lyase activity" BROAD [EC:4.1.2.11] synonym: "sorghum hydroxynitrile lyase activity" EXACT [EC:4.1.2.11] xref: EC:4.1.2.11 xref: GO:0050419 xref: MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007771 name: maltose synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate." [EC:2.4.1.139, MetaCyc:MALTOSE-SYNTHASE-RXN] synonym: "alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating)" EXACT [EC:2.4.1.139] xref: EC:2.4.1.139 xref: GO:0050420 xref: MetaCyc:MALTOSE-SYNTHASE-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007772 name: nitrite reductase (NO-forming) activity namespace: molecular_function def: "Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = NO2(-) (nitrite) + ferrocytochrome c + 2 H+." [EC:1.7.2.1, MetaCyc:NITRITE-REDUCTASE-(CYTOCHROME)-RXN] comment: Note that EC:1.7.99.3 was merged into this term. subset: gosubset_prok synonym: "[nitrite reductase (cytochrome)]" RELATED [EC:1.7.2.1] synonym: "cd-cytochrome nitrite reductase activity" NARROW [EC:1.7.2.1] synonym: "cytochrome c-551:O(2), NO(2)(+) oxidoreductase activity" NARROW [EC:1.7.2.1] synonym: "cytochrome c-551:O2, NO2+ oxidoreductase activity" EXACT [EC:1.7.2.1] synonym: "cytochrome cd activity" NARROW [EC:1.7.2.1] synonym: "cytochrome cd1 activity" NARROW [EC:1.7.2.1] synonym: "methyl viologen-nitrite reductase activity" NARROW [EC:1.7.2.1] synonym: "nitric-oxide:ferricytochrome-c oxidoreductase activity" EXACT [EC:1.7.2.1] synonym: "nitrite reductase (cytochrome) activity" EXACT [] synonym: "nitrite reductase (cytochrome; NO-forming) activity" EXACT [EC:1.7.2.1] synonym: "nitrite reductase activity" EXACT [] synonym: "Pseudomonas cytochrome oxidase activity" NARROW [EC:1.7.2.1] xref: EC:1.7.2.1 xref: GO:0016666 xref: GO:0050421 xref: MetaCyc:NITRITE-REDUCTASE-(CYTOCHROME)-RXN is_a: CCO:F0003257 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor [Term] id: CCO:F0007773 name: strictosidine beta-glucosidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + strictosidine = D-glucose + strictosidine aglycone." [EC:3.2.1.105, MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN] synonym: "strictosidine b-glucosidase activity" EXACT [] synonym: "strictosidine beta-D-glucohydrolase activity" EXACT [EC:3.2.1.105] xref: EC:3.2.1.105 xref: GO:0050422 xref: MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007774 name: thiamin oxidase activity namespace: molecular_function def: "Catalysis of the reaction: thiamin + 2 O2 = thiamin acetic acid + 2 H2O2." [EC:1.1.3.23, MetaCyc:THIAMIN-OXIDASE-RXN] synonym: "thiamin dehydrogenase activity" EXACT [EC:1.1.3.23] synonym: "thiamin:oxygen 5-oxidoreductase activity" EXACT [EC:1.1.3.23] synonym: "thiamine dehydrogenase activity" EXACT [EC:1.1.3.23] synonym: "thiamine oxidase activity" EXACT [] synonym: "thiamine:oxygen 5-oxidoreductase activity" EXACT [EC:1.1.3.23] xref: EC:1.1.3.23 xref: GO:0050423 xref: MetaCyc:THIAMIN-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007775 name: alanine carboxypeptidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups." [EC:3.4.17.6, MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN] subset: gosubset_prok synonym: "N-benzoyl-L-alanine-amidohydrolase activity" EXACT [EC:3.4.17.6] xref: EC:3.4.17.6 xref: GO:0050424 xref: MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0007776 name: carboxypeptidase B activity namespace: molecular_function def: "Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid." [EC:3.4.17.2, MetaCyc:CARBOXYPEPTIDASE-B-RXN] subset: gosubset_prok synonym: "pancreatic carboxypeptidase B" RELATED [EC:3.4.17.2] synonym: "peptidyl-L-lysine [L-arginine]hydrolase activity" EXACT [EC:3.4.17.2] synonym: "protaminase activity" RELATED [EC:3.4.17.2] synonym: "tissue carboxypeptidase B" RELATED [EC:3.4.17.2] xref: EC:3.4.17.2 xref: GO:0050425 xref: MetaCyc:CARBOXYPEPTIDASE-B-RXN is_a: CCO:F0000650 ! metallocarboxypeptidase activity [Term] id: CCO:F0007777 name: peptidyl-glycinamidase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide." [EC:3.4.19.2, MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN] synonym: "carboxamidopeptidase activity" EXACT [EC:3.4.19.2] synonym: "carboxyamidase activity" EXACT [EC:3.4.19.2] synonym: "peptidyl amino acid amide hydrolase activity" EXACT [EC:3.4.19.2] synonym: "peptidyl carboxy-amidase activity" EXACT [EC:3.4.19.2] synonym: "peptidyl carboxyamidase activity" EXACT [EC:3.4.19.2] xref: EC:3.4.19.2 xref: GO:0050426 xref: MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN is_a: CCO:F0001792 ! omega peptidase activity [Term] id: CCO:F0007778 name: calcium-dependent phospholipase C activity namespace: molecular_function def: "Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate; requires Ca2+." [EC:3.1.4.3] xref: GO:0050429 is_a: CCO:F0001003 ! phospholipase C activity [Term] id: CCO:F0007779 name: syntaxin-6 binding namespace: molecular_function def: "Interacting selectively with the SNAP receptor syntaxin-6." [GOC:ai] xref: GO:0050430 is_a: CCO:F0004214 ! syntaxin binding [Term] id: CCO:F0007780 name: transforming growth factor beta binding namespace: molecular_function def: "Interacting selectively with TGFbeta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "TGF-beta binding" EXACT [] synonym: "TGFbeta binding" EXACT [] synonym: "transforming growth factor beta ligand binding to type I receptor" RELATED [] synonym: "transforming growth factor beta ligand binding to type II receptor" RELATED [] xref: GO:0050431 is_a: CCO:F0004188 ! growth factor binding is_a: CCO:F0004221 ! cytokine binding [Term] id: CCO:F0007781 name: microfibril binding namespace: molecular_function def: "Interacting selectively with a microfibril, any small fibril occurring in biological material." [GOC:ai] comment: See also the cellular component term 'microfibril ; GO:0001527'. xref: GO:0050436 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0007783 name: 2-ethylmalate synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + H2O + 2-oxobutanoate = (R)-2-ethylmalate + CoA ." [EC:2.3.3.6, MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN] synonym: "(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating) activity" EXACT [EC:2.3.3.6] synonym: "2-ethylmalate-3-hydroxybutanedioate synthase activity" EXACT [EC:2.3.3.6] synonym: "acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)" EXACT [EC:2.3.3.6] synonym: "propylmalate synthase activity" EXACT [EC:2.3.3.6] synonym: "propylmalic synthase activity" EXACT [EC:2.3.3.6] xref: EC:2.3.3.6 xref: GO:0050438 xref: MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007784 name: 2-hydroxy-3-oxoadipate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + glyoxylate = 2-hydroxy-3-oxoadipate + CO2 ." [EC:2.2.1.5, MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN] synonym: "2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) activity" EXACT [EC:2.2.1.5] synonym: "2-hydroxy-3-oxoadipate synthetase activity" EXACT [EC:2.2.1.5] synonym: "2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)" EXACT [EC:2.2.1.5] synonym: "alpha-ketoglutaric-glyoxylic carboligase activity" EXACT [EC:2.2.1.5] synonym: "oxoglutarate: glyoxylate carboligase activity" EXACT [EC:2.2.1.5] synonym: "oxoglutarate:glyoxylate carboligase activity" EXACT [EC:2.2.1.5] xref: EC:2.2.1.5 xref: GO:0050439 xref: MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN is_a: CCO:F0003320 ! transferase activity, transferring aldehyde or ketonic groups [Term] id: CCO:F0007785 name: 2-methylcitrate synthase activity namespace: molecular_function def: "Catalysis of the reaction: propanoyl-CoA + H2O + oxaloacetate = (2R,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA." [EC:2.3.3.5, MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN] subset: gosubset_prok synonym: "2-methylcitrate oxaloacetate-lyase activity" EXACT [EC:2.3.3.5] synonym: "MCS activity" EXACT [EC:2.3.3.5] synonym: "methylcitrate synthase activity" EXACT [EC:2.3.3.5] synonym: "methylcitrate synthetase activity" EXACT [EC:2.3.3.5] synonym: "propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)" EXACT [EC:2.3.3.5] xref: EC:2.3.3.5 xref: GO:0050440 xref: MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007786 name: 3-ethylmalate synthase activity namespace: molecular_function def: "Catalysis of the reaction: butanoyl-CoA + H2O + glyoxylate = 3-ethylmalate + CoA ." [EC:2.3.3.7, MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN] synonym: "2-ethyl-3-hydroxybutanedioate synthase activity" EXACT [EC:2.3.3.7] synonym: "3-ethylmalate glyoxylate-lyase (CoA-butanoylating) activity" EXACT [EC:2.3.3.7] synonym: "butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming)" EXACT [EC:2.3.3.7] xref: EC:2.3.3.7 xref: GO:0050441 xref: MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007787 name: 3-propylmalate synthase activity namespace: molecular_function def: "Catalysis of the reaction: pentanoyl-CoA + H2O + glyoxylate = 3-propylmalate + CoA ." [EC:2.3.3.12, MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN] synonym: "3-(n-propyl)-malate synthase activity" EXACT [EC:2.3.3.12] synonym: "3-propylmalate glyoxylate-lyase (CoA-pentanoylating) activity" EXACT [EC:2.3.3.12] synonym: "beta-n-propylmalate synthase activity" EXACT [EC:2.3.3.12] synonym: "n-propylmalate synthase activity" EXACT [EC:2.3.3.12] synonym: "N-propylmalate synthase activity" EXACT [EC:2.3.3.12] synonym: "pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)" EXACT [EC:2.3.3.12] xref: EC:2.3.3.12 xref: GO:0050442 xref: MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007788 name: aquacobalamin reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+." [EC:1.16.1.5, MetaCyc:AQUACOBALAMIN-REDUCTASE-(NADPH)-RXN] synonym: "aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) activity" EXACT [EC:1.16.1.5] synonym: "aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase activity" EXACT [EC:1.16.1.5] synonym: "cob(II)alamin:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.5] synonym: "NADPH-linked aquacobalamin reductase activity" EXACT [EC:1.16.1.5] synonym: "NADPH2:aquacob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.5] synonym: "NADPH:aquacob(III)alamin oxidoreductase activity" EXACT [EC:1.16.1.5] xref: EC:1.16.1.5 xref: GO:0050444 xref: MetaCyc:AQUACOBALAMIN-REDUCTASE-(NADPH)-RXN is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0007789 name: asparagusate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD+ = asparagusate + NADH + H+." [EC:1.8.1.11, MetaCyc:ASPARAGUSATE-REDUCTASE-(NADH)-RXN] synonym: "3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase activity" EXACT [EC:1.8.1.11] synonym: "asparagusate dehydrogenase activity" EXACT [EC:1.8.1.11] synonym: "asparagusate reductase (NADH) activity" EXACT [] synonym: "asparagusate reductase (NADH2)" EXACT [EC:1.8.1.11] synonym: "asparagusic dehydrogenase activity" EXACT [EC:1.8.1.11] synonym: "NADH2:asparagusate oxidoreductase activity" EXACT [EC:1.8.1.11] synonym: "NADH:asparagusate oxidoreductase activity" EXACT [EC:1.8.1.11] xref: EC:1.8.1.11 xref: GO:0050445 xref: MetaCyc:ASPARAGUSATE-REDUCTASE-(NADH)-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007790 name: azobenzene reductase activity namespace: molecular_function def: "Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+." [EC:1.7.1.6, MetaCyc:AZOBENZENE-REDUCTASE-RXN] synonym: "azo reductase activity" BROAD [EC:1.7.1.6] synonym: "azo-dye reductase activity" BROAD [EC:1.7.1.6] synonym: "azoreductase activity" BROAD [EC:1.7.1.6] synonym: "dibromopropylaminophenylazobenzoic azoreductase activity" EXACT [EC:1.7.1.6] synonym: "dimethylaminobenzene reductase activity" EXACT [EC:1.7.1.6] synonym: "methyl red azoreductase activity" NARROW [EC:1.7.1.6] synonym: "N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.6] synonym: "N,N-dimethyl-4-phenylazoaniline azoreductase activity" EXACT [EC:1.7.1.6] synonym: "NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase activity" EXACT [EC:1.7.1.6] synonym: "NADPH-dependent azoreductase activity" BROAD [EC:1.7.1.6] synonym: "NADPH2-dependent azoreductase activity" EXACT [EC:1.7.1.6] synonym: "NADPH2:4-(dimethylamino)azobenzene oxidoreductase activity" EXACT [EC:1.7.1.6] synonym: "NADPH:4-(dimethylamino)azobenzene oxidoreductase activity" EXACT [EC:1.7.1.6] synonym: "NC-reductase activity" NARROW [EC:1.7.1.6] synonym: "new coccine (NC)-reductase" RELATED [EC:1.7.1.6] synonym: "New coccine (NC)-reductase activity" NARROW [EC:1.7.1.6] synonym: "nicotinamide adenine dinucleotide (phosphate) azoreductase activity" EXACT [EC:1.7.1.6] synonym: "orange I azoreductase activity" NARROW [EC:1.7.1.6] synonym: "orange II azoreductase activity" NARROW [EC:1.7.1.6] synonym: "p-aminoazobenzene reductase activity" EXACT [EC:1.7.1.6] synonym: "p-dimethylaminoazobenzene azoreductase activity" EXACT [EC:1.7.1.6] xref: EC:1.7.1.6 xref: GO:0050446 xref: MetaCyc:AZOBENZENE-REDUCTASE-RXN xref: UM-BBD_enzymeID:e0514 is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0007791 name: zeatin 9-aminocarboxyethyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: O-acetyl-L-serine + zeatin = lupinate + acetate." [EC:2.5.1.50, MetaCyc:BETA-(9-CYTOKININ)-ALANINE-SYNTHASE-RXN] synonym: "3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.50] synonym: "beta-(9-cytokinin)-alanine synthase activity" EXACT [] synonym: "beta-(9-cytokinin)alanine synthase activity" EXACT [EC:2.5.1.50] synonym: "lupinate synthetase activity" EXACT [EC:2.5.1.50] synonym: "lupinic acid synthase activity" EXACT [EC:2.5.1.50] synonym: "lupinic acid synthetase activity" EXACT [EC:2.5.1.50] synonym: "O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine) activity" EXACT [EC:2.5.1.50] synonym: "O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine)" EXACT [EC:2.5.1.50] synonym: "O3-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity" EXACT [EC:2.5.1.50] xref: EC:2.5.1.50 xref: GO:0050447 xref: MetaCyc:BETA-(9-CYTOKININ)-ALANINE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007792 name: beta-cyclopiazonate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: beta-cyclopiazonate + acceptor = alpha-cyclopiazonate + reduced acceptor." [EC:1.21.99.1, MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN] synonym: "b-cyclopiazonate dehydrogenase activity" EXACT [] synonym: "beta-cyclopiazonate oxidocyclase activity" EXACT [EC:1.21.99.1] synonym: "beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)" EXACT [EC:1.21.99.1] synonym: "beta-cyclopiazonate:acceptor oxidoreductase (cyclizing)" EXACT [EC:1.21.99.1] synonym: "beta-cyclopiazonic oxidocyclase activity" EXACT [EC:1.21.99.1] xref: EC:1.21.99.1 xref: GO:0050448 xref: MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN is_a: CCO:F0006306 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond [Term] id: CCO:F0007793 name: casbene synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranylgeranyl diphosphate = casbene + diphosphate." [EC:4.2.3.8, MetaCyc:CASBENE-SYNTHASE-RXN] synonym: "casbene synthetase activity" EXACT [EC:4.2.3.8] synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing)" EXACT [EC:4.2.3.8] synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming)" EXACT [EC:4.2.3.8] xref: EC:4.2.3.8 xref: GO:0050449 xref: MetaCyc:CASBENE-SYNTHASE-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007794 name: citrate (Re)-synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA ." [EC:2.3.3.3, MetaCyc:CITRATE-(RE)-SYNTHASE-RXN] synonym: "(R)-citrate synthase activity" EXACT [EC:2.3.3.3] synonym: "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]" RELATED [EC:2.3.3.3] synonym: "citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA) activity" EXACT [EC:2.3.3.3] synonym: "citrate oxaloacetate-lyase [(pro-3R)-CH2COO-rightacetyl-CoA]" RELATED [EC:2.3.3.3] synonym: "Re-citrate-synthase activity" EXACT [EC:2.3.3.3] xref: EC:2.3.3.3 xref: GO:0050450 xref: MetaCyc:CITRATE-(RE)-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007795 name: CoA-disulfide reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+." [EC:1.8.1.14, MetaCyc:COA-DISULFIDE-REDUCTASE-(NADH)-RXN] synonym: "CoA-disulfide reductase (NAD(P)H) activity" RELATED [EC:1.8.1.14] synonym: "CoA-disulfide reductase (NADH) activity" EXACT [] synonym: "CoA-disulfide reductase (NADH2)" EXACT [EC:1.8.1.14] synonym: "CoA-disulfide reductase [NAD(P)H]" RELATED [EC:1.8.1.14] synonym: "CoA-disulphide reductase activity" EXACT [] synonym: "CoA:NAD(P)+ oxidoreductase activity" EXACT [EC:1.8.1.14] synonym: "CoA:NAD+ oxidoreductase activity" EXACT [EC:1.8.1.14] synonym: "CoADR activity" EXACT [EC:1.8.1.14] synonym: "coenzyme A disulfide reductase activity" EXACT [EC:1.8.1.14] synonym: "NADH2:CoA-disulfide oxidoreductase activity" EXACT [EC:1.8.1.14] synonym: "NADH:CoA-disulfide oxidoreductase activity" EXACT [EC:1.8.1.14] xref: EC:1.8.1.14 xref: GO:0050451 xref: MetaCyc:COA-DISULFIDE-REDUCTASE-(NADH)-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007796 name: CoA-glutathione reductase activity namespace: molecular_function def: "Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+." [EC:1.8.1.10, MetaCyc:COA-GLUTATHIONE-REDUCTASE-(NADPH)-RXN] synonym: "CoA-glutathione reductase (NADPH) activity" EXACT [] synonym: "coenzyme A disulfide-glutathione reductase activity" EXACT [EC:1.8.1.10] synonym: "coenzyme A glutathione disulfide reductase activity" EXACT [EC:1.8.1.10] synonym: "glutathione:NADP+ oxidoreductase (CoA-acylating)" EXACT [EC:1.8.1.10] synonym: "NADPH-dependent coenzyme A-SS-glutathione reductase activity" EXACT [EC:1.8.1.10] synonym: "NADPH2:CoA-glutathione oxidoreductase activity" EXACT [EC:1.8.1.10] synonym: "NADPH:CoA-glutathione oxidoreductase activity" EXACT [EC:1.8.1.10] xref: EC:1.8.1.10 xref: GO:0050452 xref: MetaCyc:COA-GLUTATHIONE-REDUCTASE-(NADPH)-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007797 name: cob(II)alamin reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 cob(I)alamin + NAD+ = 2 cob(II)alamin + NADH + H+." [EC:1.16.1.4, MetaCyc:COB(II)ALAMIN-REDUCTASE-RXN] synonym: "B(12r) reductase activity" EXACT [EC:1.16.1.4] synonym: "B12r reductase activity" EXACT [EC:1.16.1.4] synonym: "cob(I)alamin:NAD+ oxidoreductase activity" EXACT [EC:1.16.1.4] synonym: "NADH2:cob(II)alamin oxidoreductase activity" EXACT [EC:1.16.1.4] synonym: "NADH:cob(II)alamin oxidoreductase activity" EXACT [EC:1.16.1.4] synonym: "vitamin B(12r) reductase activity" EXACT [EC:1.16.1.4] synonym: "vitamin B12 reductase activity" EXACT [] synonym: "vitamin B12 reduction" RELATED [] synonym: "vitamin B12r reductase activity" EXACT [EC:1.16.1.4] xref: EC:1.16.1.4 xref: GO:0050453 xref: MetaCyc:COB(II)ALAMIN-REDUCTASE-RXN is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0007798 name: coenzyme F420 hydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2 + coenzyme F420 = reduced coenzyme F420." [EC:1.12.98.1, MetaCyc:COENZYME-F420-HYDROGENASE-RXN] subset: gosubset_prok synonym: "8-hydroxy-5-deazaflavin-reducing hydrogenase activity" EXACT [EC:1.12.98.1] synonym: "coenzyme F420-dependent hydrogenase activity" EXACT [EC:1.12.98.1] synonym: "F420-reducing hydrogenase activity" EXACT [EC:1.12.98.1] synonym: "hydrogen:coenzyme F420 oxidoreductase activity" EXACT [EC:1.12.98.1] xref: EC:1.12.98.1 xref: GO:0050454 xref: MetaCyc:COENZYME-F420-HYDROGENASE-RXN is_a: CCO:F0006309 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors [Term] id: CCO:F0007799 name: columbamine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 2 columbamine + O2 = 2 berberine + 2 H2O." [EC:1.21.3.2, MetaCyc:COLUMBAMINE-OXIDASE-RXN] synonym: "berberine synthase activity" EXACT [EC:1.21.3.2] synonym: "columbamine:oxygen oxidoreductase (cyclizing)" EXACT [EC:1.21.3.2] xref: EC:1.21.3.2 xref: GO:0050455 xref: MetaCyc:COLUMBAMINE-OXIDASE-RXN is_a: CCO:F0006307 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor [Term] id: CCO:F0007800 name: cystine reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2 L-cysteine + NAD+ = L-cystine + NADH + H+." [EC:1.8.1.6, MetaCyc:CYSTINE-REDUCTASE-(NADH)-RXN] subset: gosubset_prok synonym: "cystine reductase (NADH) activity" EXACT [EC:1.8.1.6] synonym: "cystine reductase (NADH2)" EXACT [EC:1.8.1.6] synonym: "L-cysteine:NAD+ oxidoreductase" EXACT [EC:1.8.1.6] synonym: "NADH-dependent cystine reductase activity" EXACT [EC:1.8.1.6] synonym: "NADH2:L-cystine oxidoreductase" EXACT [EC:1.8.1.6] synonym: "NADH:L-cystine oxidoreductase activity" EXACT [EC:1.8.1.6] xref: EC:1.8.1.6 xref: GO:0050456 xref: MetaCyc:CYSTINE-REDUCTASE-(NADH)-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007801 name: decylcitrate synthase activity namespace: molecular_function def: "Catalysis of the reaction: lauroyl-CoA + H2O + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA ." [EC:2.3.3.2, MetaCyc:DECYLCITRATE-SYNTHASE-RXN] synonym: "(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA- acylating) activity" EXACT [EC:2.3.3.2] synonym: "(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating)" EXACT [EC:2.3.3.2] synonym: "2-decylcitrate synthase activity" EXACT [EC:2.3.3.2] synonym: "dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)" EXACT [EC:2.3.3.2] xref: EC:2.3.3.2 xref: GO:0050457 xref: MetaCyc:DECYLCITRATE-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007802 name: decylhomocitrate synthase activity namespace: molecular_function def: "Catalysis of the reaction: dodecanoyl-CoA + H2O + 2-oxoglutarate = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA ." [EC:2.3.3.4, MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN] synonym: "2-decylhomocitrate synthase activity" EXACT [EC:2.3.3.4] synonym: "3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acylating) activity" EXACT [EC:2.3.3.4] synonym: "3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)" EXACT [EC:2.3.3.4] synonym: "dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)" EXACT [EC:2.3.3.4] xref: EC:2.3.3.4 xref: GO:0050458 xref: MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007803 name: ethanolamine-phosphate phospho-lyase activity namespace: molecular_function def: "Catalysis of the reaction: ethanolamine phosphate + H2O = acetaldehyde + NH3 + phosphate." [EC:4.2.3.2, MetaCyc:ETHANOLAMINE-PHOSPHATE-PHOSPHO-LYASE-RXN] synonym: "amino alcohol O-phosphate phospholyase activity" BROAD [EC:4.2.3.2] synonym: "ethanolamine-phosphate phospho-lyase (deaminating)" EXACT [EC:4.2.3.2] synonym: "ethanolamine-phosphate phospho-lyase (deaminating; acetaldehyde-forming)" EXACT [EC:4.2.3.2] synonym: "O-phosphoethanolamine-phospholyase activity" EXACT [EC:4.2.3.2] synonym: "O-phosphorylethanol-amine phospho-lyase activity" EXACT [EC:4.2.3.2] xref: EC:4.2.3.2 xref: GO:0050459 xref: MetaCyc:ETHANOLAMINE-PHOSPHATE-PHOSPHO-LYASE-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007804 name: hydroxylamine reductase (NADH) activity namespace: molecular_function def: "Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+." [EC:1.7.1.10, MetaCyc:HYDROXYLAMINE-REDUCTASE-(NADH)-RXN] synonym: "ammonium dehydrogenase activity" EXACT [EC:1.7.1.10] synonym: "ammonium:NAD+ oxidoreductase activity" EXACT [EC:1.7.1.10] synonym: "hydroxylamine reductase (NADH2)" EXACT [EC:1.7.1.10] synonym: "N-hydroxy amine reductase activity" EXACT [EC:1.7.1.10] synonym: "NADH-hydroxylamine reductase activity" EXACT [EC:1.7.1.10] synonym: "NADH2:hydroxylamine oxidoreductase activity" EXACT [EC:1.7.1.10] synonym: "NADH:hydroxylamine oxidoreductase activity" EXACT [EC:1.7.1.10] xref: EC:1.7.1.10 xref: GO:0050460 xref: MetaCyc:HYDROXYLAMINE-REDUCTASE-(NADH)-RXN is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0007805 name: L-mimosine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O3-acetyl-L-serine + 3,4-dihydroxypyridine = 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate." [EC:2.5.1.52, MetaCyc:L-MIMOSINE-SYNTHASE-RXN] synonym: "3-O-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.52] synonym: "O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl) activity" EXACT [EC:2.5.1.52] synonym: "O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl)" EXACT [EC:2.5.1.52] synonym: "O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.52] xref: EC:2.5.1.52 xref: GO:0050461 xref: MetaCyc:L-MIMOSINE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007806 name: N-acetylneuraminate synthase activity namespace: molecular_function def: "Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate ." [EC:2.5.1.56, MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN] synonym: "(NANA)condensing enzyme activity" EXACT [EC:2.5.1.56] synonym: "N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity" EXACT [EC:2.5.1.56] synonym: "N-acetylneuraminic acid synthase activity" EXACT [EC:2.5.1.56] synonym: "NeuAc synthase activity" EXACT [EC:2.5.1.56] synonym: "phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)" EXACT [EC:2.5.1.56] xref: EC:2.5.1.56 xref: GO:0050462 xref: MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007807 name: nitrate reductase [NAD(P)H] activity namespace: molecular_function def: "Catalysis of the reaction: NO2- (nitrite) + NAD(P)+ + H2O = NO3- (nitrate) + NAD(P)H + H+." [EC:1.7.1.2, MetaCyc:NITRATE-REDUCTASE-(NAD(P)H)-RXN] synonym: "assimilatory NAD(P)H-nitrate reductase activity" RELATED [EC:1.7.1.2] synonym: "assimilatory nitrate reductase activity" RELATED [EC:1.7.1.2] synonym: "NAD(P)H bispecific nitrate reductase activity" EXACT [EC:1.7.1.2] synonym: "NAD(P)H-nitrate reductase activity" EXACT [EC:1.7.1.2] synonym: "NAD(P)H2:nitrate oxidoreductase activity" EXACT [EC:1.7.1.2] synonym: "NAD(P)H:nitrate oxidoreductase activity" EXACT [EC:1.7.1.2] synonym: "nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity" EXACT [EC:1.7.1.2] synonym: "nitrate reductase [NAD(P)H2]" RELATED [EC:1.7.1.2] synonym: "nitrate reductase NAD(P)H activity" EXACT [EC:1.7.1.2] synonym: "nitrite:NAD(P)+ oxidoreductase activity" EXACT [EC:1.7.1.2] xref: EC:1.7.1.2 xref: GO:0050463 xref: MetaCyc:NITRATE-REDUCTASE-(NAD(P)H)-RXN is_a: CCO:F0002276 ! nitrate reductase activity is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0007808 name: nitrate reductase (NADPH) activity namespace: molecular_function def: "Catalysis of the reaction: NO2- (nitrite) + NADP+ + H2O = NO3- (nitrate) + NADPH + H+." [EC:1.7.1.3, MetaCyc:NITRATE-REDUCTASE-(NADPH)-RXN] synonym: "assimilatory NADPH-nitrate reductase activity" EXACT [EC:1.7.1.3] synonym: "assimilatory nitrate reductase activity" BROAD [EC:1.7.1.3] synonym: "assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase activity" EXACT [EC:1.7.1.3] synonym: "NADPH-nitrate reductase activity" EXACT [EC:1.7.1.3] synonym: "NADPH:nitrate oxidoreductase activity" EXACT [EC:1.7.1.3] synonym: "NADPH:nitrate reductase activity" EXACT [EC:1.7.1.3] synonym: "nitrate reductase (NADPH(2)) activity" EXACT [EC:1.7.1.3] synonym: "nitrate reductase (NADPH2)" EXACT [EC:1.7.1.3] synonym: "nitrite:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.3] synonym: "triphosphopyridine nucleotide-nitrate reductase activity" EXACT [EC:1.7.1.3] xref: EC:1.7.1.3 xref: GO:0050464 xref: MetaCyc:NITRATE-REDUCTASE-(NADPH)-RXN is_a: CCO:F0002276 ! nitrate reductase activity is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0007809 name: nitroquinoline-N-oxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+." [EC:1.7.1.9, MetaCyc:1.7.1.9-RXN] synonym: "4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity" EXACT [EC:1.7.1.9] synonym: "4-nitroquinoline 1-oxide reductase activity" EXACT [EC:1.7.1.9] synonym: "4NQO reductase activity" EXACT [EC:1.7.1.9] synonym: "NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity" EXACT [EC:1.7.1.9] synonym: "NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity" EXACT [EC:1.7.1.9] xref: EC:1.7.1.9 xref: GO:0050465 xref: MetaCyc:1.7.1.9-RXN is_a: CCO:F0006253 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor [Term] id: CCO:F0007810 name: pentalenene synthase activity namespace: molecular_function def: "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = pentalenene + diphosphate." [EC:4.2.3.7, MetaCyc:PENTALENENE-SYNTHASE-RXN] subset: gosubset_prok synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming)" EXACT [EC:4.2.3.7] synonym: "2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)" EXACT [EC:4.2.3.7] synonym: "pentalenene synthetase activity" EXACT [EC:4.2.3.7] xref: EC:4.2.3.7 xref: GO:0050467 xref: MetaCyc:PENTALENENE-SYNTHASE-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007811 name: reticuline oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-reticuline + O2 = (S)-scoulerine + H2O2." [EC:1.21.3.3, MetaCyc:RETICULINE-OXIDASE-RXN] synonym: "(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)" EXACT [EC:1.21.3.3] synonym: "BBE" RELATED [EC:1.21.3.3] synonym: "berberine bridge enzyme activity" EXACT [EC:1.21.3.3] synonym: "berberine-bridge-forming enzyme activity" EXACT [EC:1.21.3.3] synonym: "tetrahydroprotoberberine synthase activity" EXACT [EC:1.21.3.3] xref: EC:1.21.3.3 xref: GO:0050468 xref: MetaCyc:RETICULINE-OXIDASE-RXN is_a: CCO:F0006307 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor [Term] id: CCO:F0007812 name: sabinene-hydrate synthase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + geranyl-PP = pyrophosphate + sabinene hydrate." [EC:4.2.3.11, MetaCyc:4.2.3.11-RXN] synonym: "geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming)" EXACT [EC:4.2.3.11] synonym: "sabinene hydrate cyclase activity" EXACT [EC:4.2.3.11] xref: EC:4.2.3.11 xref: GO:0050469 xref: MetaCyc:4.2.3.11-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007813 name: trimethylamine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein." [EC:1.5.8.2, MetaCyc:1.5.8.2-RXN] subset: gosubset_prok synonym: "TMADh activity" EXACT [EC:1.5.8.2] synonym: "trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)" EXACT [EC:1.5.8.2] xref: EC:1.5.8.2 xref: GO:0050470 xref: MetaCyc:1.5.8.2-RXN xref: UM-BBD_enzymeID:e0854 is_a: CCO:F0006311 ! oxidoreductase activity, acting on the CH-NH group of donors, with a flavin as acceptor [Term] id: CCO:F0007814 name: uracilylalanine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate." [EC:2.5.1.53, MetaCyc:URACILYLALANINE-SYNTHASE-RXN] synonym: "3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.53] synonym: "isowillardiine synthase activity" EXACT [EC:2.5.1.53] synonym: "O(3)-acetyl-L-serine acetate-lyase (adding uracil) activity" EXACT [EC:2.5.1.53] synonym: "O3-acetyl-L-serine acetate-lyase (adding uracil)" EXACT [EC:2.5.1.53] synonym: "O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity" EXACT [EC:2.5.1.53] synonym: "willardiine synthase activity" EXACT [EC:2.5.1.53] synonym: "Willardiine synthase activity" EXACT [EC:2.5.1.53] xref: EC:2.5.1.53 xref: GO:0050471 xref: MetaCyc:URACILYLALANINE-SYNTHASE-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007815 name: zeatin reductase activity namespace: molecular_function def: "Catalysis of the reaction: dihydrozeatin + NADP+ = zeatin + NADPH." [EC:1.3.1.69, MetaCyc:ZEATIN-REDUCTASE-RXN] synonym: "dihydrozeatin:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.69] xref: EC:1.3.1.69 xref: GO:0050472 xref: MetaCyc:ZEATIN-REDUCTASE-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007816 name: arachidonate 15-lipoxygenase activity namespace: molecular_function def: "Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate." [EC:1.13.11.33] subset: gosubset_prok synonym: "15-lipoxygenase activity" EXACT [EC:1.13.11.33] synonym: "arachidonate omega(6) lipoxygenase activity" EXACT [EC:1.13.11.33] synonym: "arachidonate omega6 lipoxygenase activity" EXACT [EC:1.13.11.33] synonym: "arachidonate:oxygen 15-oxidoreductase activity" EXACT [EC:1.13.11.33] synonym: "linoleic acid omega6-lipoxygenase activity" EXACT [EC:1.13.11.33] synonym: "omega6 lipoxygenase activity" EXACT [EC:1.13.11.33] xref: EC:1.13.11.33 xref: GO:0050473 xref: MetaCyc:ARACHIDONATE-15-LIPOXYGENASE-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007818 name: acetylenedicarboxylate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate." [EC:4.1.1.78] synonym: "acetylenedicarboxylate carboxy-lyase (pyruvate-forming)" EXACT [EC:4.1.1.78] synonym: "acetylenedicarboxylate carboxy-lyase activity" EXACT [EC:4.1.1.78] synonym: "acetylenedicarboxylate hydrase activity" EXACT [EC:4.1.1.78] synonym: "acetylenedicarboxylate hydratase activity" EXACT [EC:4.1.1.78] xref: EC:4.1.1.78 xref: GO:0050476 xref: MetaCyc:4.1.1.78-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007819 name: acyl-lysine deacylase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate." [EC:3.5.1.17] synonym: "6-N-acyl-L-lysine amidohydrolase activity" EXACT [EC:3.5.1.17] synonym: "epsilon-lysine acylase activity" EXACT [EC:3.5.1.17] synonym: "N6-acyl-L-lysine amidohydrolase activity" EXACT [EC:3.5.1.17] xref: EC:3.5.1.17 xref: GO:0050477 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007820 name: anthranilate 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + anthranilate + (tetrahydrobiopterin/tetrahydropteridine) = 3-hydroxanthranilate + H2O + (dihydrobiopterin/dihydropteridine)." [EC:1.14.16.3, MetaCyc:ANTHRANILATE-3-MONOOXYGENASE-RXN] synonym: "anthranilate 3-hydroxylase activity" EXACT [] synonym: "anthranilate,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.16.3] synonym: "anthranilic acid hydroxylase activity" BROAD [EC:1.14.16.3] synonym: "anthranilic hydroxylase activity" BROAD [EC:1.14.16.3] xref: EC:1.14.16.3 xref: GO:0050478 xref: MetaCyc:ANTHRANILATE-3-MONOOXYGENASE-RXN is_a: CCO:F0003297 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007821 name: glyceryl-ether monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine)." [EC:1.14.16.5, MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN] synonym: "1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase activity" EXACT [EC:1.14.16.5] synonym: "alkylglycerol monooxygenase activity" EXACT [EC:1.14.16.5] synonym: "glyceryl ether oxygenase activity" EXACT [EC:1.14.16.5] synonym: "glyceryl etherase activity" EXACT [EC:1.14.16.5] synonym: "glyceryl-ether cleaving enzyme activity" EXACT [EC:1.14.16.5] synonym: "O-alkylglycerol monooxygenase activity" EXACT [EC:1.14.16.5] xref: EC:1.14.16.5 xref: GO:0050479 xref: MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN is_a: CCO:F0003297 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007822 name: imidazolonepropionase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate + H2O = H+ + N-formimidoyl-L-glutamate." [EC:3.5.2.7, MetaCyc:IMIDAZOLONEPROPIONASE-RXN] subset: gosubset_prok synonym: "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase activity" EXACT [EC:3.5.2.7] synonym: "4(5)-imidazolone-5(4)-propionic acid hydrolase activity" EXACT [EC:3.5.2.7] synonym: "imidazolone propionic acid hydrolase activity" EXACT [EC:3.5.2.7] synonym: "imidazolone-5-propionate hydrolase activity" EXACT [EC:3.5.2.7] xref: EC:3.5.2.7 xref: GO:0050480 xref: MetaCyc:IMIDAZOLONEPROPIONASE-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0007823 name: mandelate 4-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + O2 + (tetrahydrobiopterin/tetrahydropteridine) = (S)-4-hydroxymandelate + H2O + (dihydrobiopterin/dihydropteridine). (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate." [EC:1.14.16.6, MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN] synonym: "(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)" EXACT [EC:1.14.16.6] synonym: "L-mandelate 4-hydroxylase activity" EXACT [] synonym: "mandelic acid 4-hydroxylase activity" EXACT [EC:1.14.16.6] xref: EC:1.14.16.6 xref: GO:0050481 xref: MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN is_a: CCO:F0003297 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007824 name: IMP 5'-nucleotidase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate." [GOC:ai] synonym: "IMP 5' nucleotidase activity" EXACT [] synonym: "IMP-GMP specific 5'-nucleotidase activity" NARROW [] xref: GO:0050483 is_a: CCO:F0001796 ! 5'-nucleotidase activity [Term] id: CCO:F0007825 name: GMP 5'-nucleotidase activity namespace: molecular_function def: "Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate." [GOC:ai] synonym: "GMP 5' nucleotidase activity" EXACT [] synonym: "IMP-GMP specific 5'-nucleotidase activity" NARROW [] xref: GO:0050484 is_a: CCO:F0001796 ! 5'-nucleotidase activity [Term] id: CCO:F0007826 name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide." [GOC:ai] subset: gosubset_prok synonym: "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor" EXACT [] xref: EC:1.21.4 xref: GO:0050485 is_a: CCO:F0006306 ! oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond [Term] id: CCO:F0007827 name: intramolecular transferase activity, transferring hydroxy groups namespace: molecular_function def: "Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule." [GOC:mah] subset: gosubset_prok xref: EC:5.4.4 xref: GO:0050486 is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0007828 name: sulfoacetaldehyde acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: SO3(2-) (sulfite) + acetyl phosphate = 2-sulfoacetaldehyde + phosphate." [EC:2.3.3.15] comment: Note that the enzyme sulfoacetaldehyde acetyltransferase also has sulfoacetaldehyde lyase activity (GO:0050312). subset: gosubset_prok synonym: "acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming)" EXACT [EC:2.3.3.15] synonym: "sulphoacetaldehyde acetyltransferase activity" EXACT [] xref: EC:2.3.3.15 xref: GO:0050487 is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0007829 name: ecdysteroid UDP-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid." [GOC:ai] synonym: "ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity" RELATED [] xref: GO:0050488 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007830 name: ecdysteroid UDP-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucuronate + ecdysteroid = UDP + glucuronosyl-ecdysteroid." [GOC:ai] synonym: "ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity" RELATED [] xref: GO:0050489 is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0007831 name: 1,4-lactonase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid." [EC:3.1.1.25, MetaCyc:1] synonym: "1,4-lactone hydroxyacylhydrolase activity" EXACT [EC:3.1.1.25] synonym: "gamma-lactonase activity" EXACT [EC:3.1.1.25] xref: EC:3.1.1.25 xref: GO:0050490 xref: MetaCyc:1 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007832 name: sulcatone reductase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + sulcatol = NADH + H+ + sulcatone." [EC:1.1.1.260, MetaCyc:1.1.1.260-RXN] synonym: "sulcatol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.260] xref: EC:1.1.1.260 xref: GO:0050491 xref: MetaCyc:1.1.1.260-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007833 name: glycerol-1-phosphate dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate." [EC:1.1.1.261, MetaCyc:1.1.1.261-RXN] subset: gosubset_prok synonym: "sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.261] xref: EC:1.1.1.261 xref: GO:0050492 xref: MetaCyc:1.1.1.261-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007834 name: transferase activity, transferring alkylthio groups namespace: molecular_function def: "Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor)." [GOC:ai] subset: gosubset_prok xref: EC:2.8.4 xref: GO:0050497 is_a: CCO:F0003354 ! transferase activity, transferring sulfur-containing groups [Term] id: CCO:F0007835 name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated." [GOC:mah] subset: gosubset_prok xref: EC:1.14.20 xref: GO:0050498 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007836 name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H." [GOC:mah] subset: gosubset_prok xref: EC:1.20.1 xref: GO:0050499 is_a: CCO:F0004500 ! oxidoreductase activity, acting on phosphorus or arsenic in donors [Term] id: CCO:F0007837 name: 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1,3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate." [EC:2.4.1.211, MetaCyc:2.4.1.211-RXN] synonym: "1,3-b-galactosyl-N-acetylhexosamine phosphorylase activity" EXACT [] synonym: "beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity" EXACT [EC:2.4.1.211] xref: EC:2.4.1.211 xref: GO:0050500 xref: MetaCyc:2.4.1.211-RXN is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0007838 name: hyaluronan synthase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)](n) + 2n UDP." [EC:2.4.1.212, MetaCyc:2.4.1.212-RXN] subset: gosubset_prok synonym: "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity" EXACT [EC:2.4.1.212] synonym: "HAS activity" EXACT [EC:2.4.1.212] synonym: "seHAS" RELATED [EC:2.4.1.212] synonym: "spHAS" RELATED [EC:2.4.1.212] xref: EC:2.4.1.212 xref: GO:0050501 xref: MetaCyc:2.4.1.212-RXN is_a: CCO:F0001774 ! UDP-glycosyltransferase activity is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007839 name: cis-zeatin O-beta-D-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + UDP." [EC:2.4.1.215, MetaCyc:2.4.1.215-RXN] synonym: "cis-zeatin O-b-D-glucosyltransferase activity" EXACT [] synonym: "UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.215] synonym: "UDPglucose:cis-zeatin O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.215] xref: EC:2.4.1.215 xref: GO:0050502 xref: MetaCyc:2.4.1.215-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007840 name: trehalose 6-phosphate phosphorylase activity namespace: molecular_function def: "Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate." [EC:2.4.1.216, MetaCyc:2.4.1.216-RXN] subset: gosubset_prok synonym: "trehalose 6-phosphate:phosphate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.216] xref: EC:2.4.1.216 xref: GO:0050503 xref: MetaCyc:2.4.1.216-RXN is_a: CCO:F0001019 ! phosphorylase activity [Term] id: CCO:F0007841 name: mannosyl-3-phosphoglycerate synthase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-mannose + 3-phospho-D-glycerate = GDP + 2-(alpha-D-mannosyl)-3-phosphoglycerate." [EC:2.4.1.217, MetaCyc:2.4.1.217-RXN] subset: gosubset_prok synonym: "GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.217] synonym: "MPG synthase activity" EXACT [EC:2.4.1.217] xref: EC:2.4.1.217 xref: GO:0050504 xref: MetaCyc:2.4.1.217-RXN is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0007842 name: hydroquinone glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: hydroquinone + UDP-D-glucose = hydroquinone-O-beta-D-glucopyranoside + UDP." [EC:2.4.1.218, MetaCyc:2.4.1.218-RXN] synonym: "arbutin synthase activity" EXACT [EC:2.4.1.218] synonym: "hydroquinone:O-glucosyltransferase activity" EXACT [EC:2.4.1.218] synonym: "UDP-glucose:hydroquinone-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.218] synonym: "UDPglucose:hydroquinone-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.218] xref: EC:2.4.1.218 xref: GO:0050505 xref: MetaCyc:2.4.1.218-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007843 name: vomilenine glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: vomilenine + UDP-D-glucose = raucaffricine + UDP." [EC:2.4.1.219, MetaCyc:2.4.1.219-RXN] synonym: "UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.219] synonym: "UDPG:vomilenine 21-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.219] synonym: "UDPG:vomilenine 21beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.219] synonym: "vomilenine-glucosyltransferase activity" EXACT [EC:2.4.1.219] xref: EC:2.4.1.219 xref: GO:0050506 xref: MetaCyc:2.4.1.219-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007844 name: indoxyl-UDPG glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: indoxyl + UDP-D-glucose = indican + UDP." [EC:2.4.1.220, MetaCyc:2.4.1.220-RXN] synonym: "indoxyl-UDPG-glucosyltransferase activity" EXACT [EC:2.4.1.220] synonym: "UDP-glucose:indoxyl 3-O-beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.220] xref: EC:2.4.1.220 xref: GO:0050507 xref: MetaCyc:2.4.1.220-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007845 name: glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP." [EC:2.4.1.224, MetaCyc:2.4.1.224-RXN] synonym: "alpha-N-acetylglucosaminyltransferase II activity" EXACT [EC:2.4.1.224] synonym: "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity" EXACT [] synonym: "glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.224] synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.224] xref: EC:2.4.1.224 xref: GO:0050508 xref: MetaCyc:2.4.1.224-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0007846 name: N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP." [EC:2.4.1.225, MetaCyc:2.4.1.225-RXN] synonym: "heparan glucuronyltransferase II activity" EXACT [EC:2.4.1.225] synonym: "N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity" EXACT [] synonym: "N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity" EXACT [EC:2.4.1.225] synonym: "UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity" EXACT [EC:2.4.1.225] xref: EC:2.4.1.225 xref: GO:0050509 xref: MetaCyc:2.4.1.225-RXN is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0007847 name: N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP." [EC:2.4.1.226, MetaCyc:2.4.1.226-RXN] synonym: "alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity" EXACT [EC:2.4.1.226] synonym: "chondroitin glucuronyltransferase II activity" EXACT [EC:2.4.1.226] synonym: "N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity" EXACT [] xref: EC:2.4.1.226 xref: GO:0050510 xref: MetaCyc:2.4.1.226-RXN is_a: CCO:F0002526 ! glucuronosyltransferase activity [Term] id: CCO:F0007848 name: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP." [EC:2.4.1.227, MetaCyc:2.4.1.227-RXN] subset: gosubset_prok synonym: "MurG transferase activity" RELATED [EC:2.4.1.227] synonym: "UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity" EXACT [EC:2.4.1.227] synonym: "UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase activity" EXACT [EC:2.4.1.227] synonym: "undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase activity" EXACT [EC:2.4.1.227] synonym: "undecaprenyldiphospho-muramoylpentapeptide b-N-acetylglucosaminyltransferase activity" EXACT [] xref: EC:2.4.1.227 xref: GO:0050511 xref: MetaCyc:2.4.1.227-RXN is_a: CCO:F0001851 ! acetylglucosaminyltransferase activity [Term] id: CCO:F0007849 name: lactosylceramide 4-alpha-galactosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP." [EC:2.4.1.228, MetaCyc:2.4.1.228-RXN] synonym: "Gal-beta-1-4Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228] synonym: "galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228] synonym: "globotriaosylceramide/CD77 synthase activity" NARROW [EC:2.4.1.228] synonym: "histo-blood group P(k) UDP-galactose activity" NARROW [EC:2.4.1.228] synonym: "histo-blood group Pk UDP-galactose" RELATED [EC:2.4.1.228] synonym: "lactosylceramide 4-a-galactosyltransferase activity" EXACT [] synonym: "UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.228] xref: EC:2.4.1.228 xref: GO:0050512 xref: MetaCyc:2.4.1.228-RXN is_a: CCO:F0005579 ! UDP-galactosyltransferase activity [Term] id: CCO:F0007850 name: glycoprotein 2-beta-D-xylosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-N-acetyl-beta-D-glucosaminyl}asparagine + UDP-L-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-[beta-D-xylosyl-(1,2)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-N-acetyl-beta-D-glucosaminyl}asparagine + UDP." [EC:2.4.2.38, MetaCyc:2.4.2.38-RXN] synonym: "beta-1,2-xylosyltransferase activity" EXACT [EC:2.4.2.38] synonym: "beta1,2-xylosyltransferase activity" EXACT [EC:2.4.2.38] synonym: "glycoprotein 2-b-D-xylosyltransferase activity" EXACT [] xref: EC:2.4.2.38 xref: GO:0050513 xref: MetaCyc:2.4.2.38-RXN is_a: CCO:F0005581 ! UDP-xylosyltransferase activity [Term] id: CCO:F0007851 name: homospermidine synthase (spermidine-specific) activity namespace: molecular_function def: "Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine." [EC:2.5.1.45, MetaCyc:2.5.1.45-RXN] synonym: "spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming)" EXACT [EC:2.5.1.45] xref: EC:2.5.1.45 xref: GO:0050514 xref: MetaCyc:2.5.1.45-RXN is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0007852 name: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol." [EC:2.7.1.148, MetaCyc:2.7.1.148-RXN] subset: gosubset_prok synonym: "4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity" EXACT [EC:2.7.1.148] synonym: "4-diphosphocytidyl-2C-methyl-D-erythritol kinase activity" EXACT [] synonym: "ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity" EXACT [EC:2.7.1.148] synonym: "CDP-ME kinase activity" EXACT [EC:2.7.1.148] synonym: "CMK activity" RELATED [EC:2.7.1.148] xref: EC:2.7.1.148 xref: GO:0008698 xref: GO:0050515 xref: MetaCyc:2.7.1.148-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0007853 name: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol." [EC:2.7.7.60, MetaCyc:2.7.7.60-RXN] subset: gosubset_prok synonym: "4-diphosphocytidyl-2-C-methyl-D-erythritol synthase activity" EXACT [EC:2.7.7.60] synonym: "4-diphosphocytidyl-2C-methyl-D-erythritol synthase activity" EXACT [] synonym: "CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity" EXACT [] synonym: "MCT activity" RELATED [EC:2.7.7.60] synonym: "MEP cytidylyltransferase activity" EXACT [] xref: EC:2.7.7.60 xref: GO:0008699 xref: GO:0050518 xref: MetaCyc:2.7.7.60-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0007854 name: holo-citrate lyase synthase activity namespace: molecular_function def: "Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = pyrophosphate + holo-citrate lyase." [EC:2.7.7.61, MetaCyc:2.7.7.61-RXN] subset: gosubset_prok synonym: "2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase activity" EXACT [EC:2.7.7.61] synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase activity" EXACT [EC:2.7.7.61] synonym: "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity" EXACT [EC:2.7.7.61] synonym: "CitX" RELATED [EC:2.7.7.61] synonym: "holo-ACP synthase activity" RELATED [EC:2.7.7.61] xref: EC:2.7.7.61 xref: GO:0050519 xref: MetaCyc:2.7.7.61-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0007855 name: phosphatidylcholine synthase activity namespace: molecular_function def: "Catalysis of the reaction: CDP-diacylglycerol + choline = CMP + phosphatidylcholine." [EC:2.7.8.24, MetaCyc:2.7.8.24-RXN] subset: gosubset_prok synonym: "CDP-diacylglycerol:choline O-phosphatidyltransferase activity" EXACT [EC:2.7.8.24] synonym: "CDP-diglyceride-choline O-phosphatidyltransferase activity" EXACT [EC:2.7.8.24] synonym: "CDPdiglyceride-choline O-phosphatidyltransferase activity" EXACT [EC:2.7.8.24] synonym: "PC synthase activity" EXACT [EC:2.7.8.24] xref: EC:2.7.8.24 xref: GO:0050520 xref: MetaCyc:2.7.8.24-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0007856 name: alpha-glucan, water dikinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate." [EC:2.7.9.4, MetaCyc:2.7.9.4-RXN] synonym: "a-glucan, water dikinase activity" EXACT [] synonym: "alpha-glucan,water dikinase activity" EXACT [EC:2.7.9.4] synonym: "ATP:alpha-glucan, water phosphotransferase activity" EXACT [EC:2.7.9.4] synonym: "GWD" RELATED [EC:2.7.9.4] synonym: "starch-related R1 protein activity" EXACT [EC:2.7.9.4] xref: EC:2.7.9.4 xref: GO:0050521 xref: MetaCyc:2.7.9.4-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003353 ! phosphotransferase activity, paired acceptors [Term] id: CCO:F0007857 name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP." [GOC:ai] subset: gosubset_prok xref: EC:1.20.98 xref: GO:0050522 is_a: CCO:F0004500 ! oxidoreductase activity, acting on phosphorus or arsenic in donors [Term] id: CCO:F0007858 name: coenzyme-B sulfoethylthiotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-(methylthio)ethanesulfonate + N-(7-mercaptoheptanoyl)threonine 3-O-phosphate = CoM-S-S-CoB + methane. 2-(methylthio)ethanesulfonate is also known as methyl-CoM; N-(7-mercaptoheptanoyl)threonine 3-O-phosphate is also known as coenzyme B." [EC:2.8.4.1, MetaCyc:2.8.4.1-RXN] subset: gosubset_prok synonym: "2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase activity" EXACT [EC:2.8.4.1] synonym: "coenzyme-B sulphoethylthiotransferase activity" EXACT [] synonym: "methyl coenzyme M reductase activity" EXACT [EC:2.8.4.1] synonym: "methyl-CoM reductase activity" EXACT [EC:2.8.4.1] xref: EC:2.8.4.1 xref: GO:0050524 xref: MetaCyc:2.8.4.1-RXN is_a: CCO:F0007834 ! transferase activity, transferring alkylthio groups [Term] id: CCO:F0007859 name: cutinase activity namespace: molecular_function def: "Catalysis of the reaction: cutin + H2O = cutin monomers." [EC:3.1.1.74, MetaCyc:3.1.1.74-RXN] subset: gosubset_prok synonym: "cutin hydrolase activity" EXACT [EC:3.1.1.74] xref: EC:3.1.1.74 xref: GO:0050525 xref: MetaCyc:3.1.1.74-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007860 name: poly(3-hydroxybutyrate) depolymerase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x = 1-5." [EC:3.1.1.75, MetaCyc:3.1.1.75-RXN] subset: gosubset_prok synonym: "PHB depolymerase activity" EXACT [EC:3.1.1.75] synonym: "poly((R)-hydroxyalkanoic acid) depolymerase activity" BROAD [EC:3.1.1.75] synonym: "poly(3HB) depolymerase activity" EXACT [EC:3.1.1.75] synonym: "poly(HA(SCL)) depolymerase activity" EXACT [EC:3.1.1.75] synonym: "poly(HA) depolymerase activity" RELATED [EC:3.1.1.75] synonym: "poly(HASCL) depolymerase activity" EXACT [EC:3.1.1.75] synonym: "poly[(R)-3-hydroxybutyrate] hydrolase activity" EXACT [EC:3.1.1.75] synonym: "poly[(R)-hydroxyalkanoic acid] depolymerase" BROAD [EC:3.1.1.75] xref: EC:3.1.1.75 xref: GO:0050526 xref: MetaCyc:3.1.1.75-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007861 name: poly(3-hydroxyoctanoate) depolymerase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x = 1-5." [EC:3.1.1.76, MetaCyc:3.1.1.76-RXN] subset: gosubset_prok synonym: "PHA depolymerase activity" BROAD [EC:3.1.1.76] synonym: "PHO depolymerase activity" EXACT [EC:3.1.1.76] synonym: "poly((R)-3-hydroxyoctanoate) hydrolase activity" EXACT [EC:3.1.1.76] synonym: "poly((R)-hydroxyalkanoic acid) depolymerase activity" BROAD [EC:3.1.1.76] synonym: "poly(3HO) depolymerase activity" EXACT [EC:3.1.1.76] synonym: "poly(HA(MCL)) depolymerase activity" EXACT [EC:3.1.1.76] synonym: "poly(HA) depolymerase activity" BROAD [EC:3.1.1.76] synonym: "poly(HAMCL) depolymerase activity" EXACT [EC:3.1.1.76] synonym: "poly[(R)-3-hydroxyoctanoate] hydrolase activity" EXACT [EC:3.1.1.76] synonym: "poly[(R)-hydroxyalkanoic acid] depolymerase" BROAD [EC:3.1.1.76] synonym: "poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase activity" EXACT [EC:3.1.1.76] xref: EC:3.1.1.76 xref: GO:0050527 xref: MetaCyc:3.1.1.76-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007862 name: acyloxyacyl hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid." [EC:3.1.1.77, MetaCyc:3.1.1.77-RXN] xref: EC:3.1.1.77 xref: GO:0050528 xref: MetaCyc:3.1.1.77-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007863 name: polyneuridine-aldehyde esterase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + polyneuridine aldehyde = methanol + CO2 + 16-epivellosimine." [EC:3.1.1.78, MetaCyc:3.1.1.78-RXN] synonym: "PNAE activity" EXACT [EC:3.1.1.78] synonym: "polyneuridine aldehyde esterase activity" EXACT [EC:3.1.1.78] synonym: "polyneuridine aldehyde hydrolase (decarboxylating)" EXACT [EC:3.1.1.78] xref: EC:3.1.1.78 xref: GO:0050529 xref: MetaCyc:3.1.1.78-RXN is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0007864 name: glucosylglycerol 3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2-(beta-D-glucosyl)-sn-glycerol-3-phosphate + H2O = 2-(beta-D-glucosyl)-sn-glycerol + phosphate." [EC:3.1.3.69, MetaCyc:3.1.3.69-RXN] subset: gosubset_prok synonym: "2-(beta-D-glucosyl)-sn-glycerol-3-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.69] synonym: "salt tolerance protein A" RELATED [EC:3.1.3.69] synonym: "StpA" RELATED [EC:3.1.3.69] xref: EC:3.1.3.69 xref: GO:0050530 xref: MetaCyc:3.1.3.69-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007865 name: mannosyl-3-phosphoglycerate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2(alpha-D-mannosyl)-D-glycerate + phosphate." [EC:3.1.3.70, MetaCyc:3.1.3.70-RXN] subset: gosubset_prok synonym: "alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity" EXACT [EC:3.1.3.70] xref: EC:3.1.3.70 xref: GO:0050531 xref: MetaCyc:3.1.3.70-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007866 name: 2-phosphosulfolactate phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2-phospho-3-sulfolactate + H2O = 3-sulfolactate + phosphate." [EC:3.1.3.71, MetaCyc:3.1.3.71-RXN] subset: gosubset_prok synonym: "(2R)-phosphosulfolactate phosphohydrolase activity" EXACT [EC:3.1.3.71] synonym: "(R)-2-phospho-3-sulfolactate phosphohydrolase activity" EXACT [EC:3.1.3.71] synonym: "2-phosphosulpholactate phosphatase activity" EXACT [] synonym: "ComB phosphatase activity" RELATED [EC:3.1.3.71] xref: EC:3.1.3.71 xref: GO:0050532 xref: MetaCyc:R229-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007867 name: 5-phytase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate." [EC:3.1.3.72, MetaCyc:3.1.3.72-RXN] synonym: "myo-inositol-hexakisphosphate 5-phosphohydrolase activity" EXACT [EC:3.1.3.72] xref: EC:3.1.3.72 xref: GO:0050533 xref: MetaCyc:3.1.3.72-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0007868 name: 3-deoxyoctulosonase activity namespace: molecular_function def: "Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide." [EC:3.2.1.144, MetaCyc:3.2.1.144-RXN] synonym: "3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity" EXACT [EC:3.2.1.144] synonym: "alpha-Kdo-ase activity" EXACT [EC:3.2.1.144] xref: EC:3.2.1.144 xref: GO:0050534 xref: MetaCyc:3.2.1.144-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007869 name: beta-primeverosidase activity namespace: molecular_function def: "Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol." [EC:3.2.1.149, MetaCyc:3.2.1.149-RXN] synonym: "6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase activity" EXACT [EC:3.2.1.149] synonym: "b-primeverosidase activity" EXACT [] xref: EC:3.2.1.149 xref: GO:0050535 xref: MetaCyc:3.2.1.149-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0007871 name: mandelamide amidase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-mandelamide + H2O = (R)-mandelate + NH3." [EC:3.5.1.86, MetaCyc:3.5.1.86-RXN] synonym: "mandelamide hydrolase activity" EXACT [EC:3.5.1.86] synonym: "Pseudomonas mandelamide hydrolase activity" EXACT [EC:3.5.1.86] xref: EC:3.5.1.86 xref: GO:0050537 xref: MetaCyc:3.5.1.86-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007872 name: N-carbamoyl-L-amino-acid hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-carbamoyl-L-2-amino acid (a 2-ureido carboxylate) + H2O = L-2-amino acid + NH3 + CO2." [EC:3.5.1.87, MetaCyc:3.5.1.87-RXN] subset: gosubset_prok synonym: "L-carbamoylase activity" EXACT [EC:3.5.1.87] synonym: "N-carbamoyl-L-amino acid amidohydrolase activity" EXACT [EC:3.5.1.87] xref: EC:3.5.1.87 xref: GO:0050538 xref: MetaCyc:3.5.1.87-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007873 name: maleimide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: maleimide + H2O = maleamic acid." [EC:3.5.2.16, MetaCyc:3.5.2.16-RXN] synonym: "cyclic imide hydrolase activity" EXACT [EC:3.5.2.16] synonym: "cyclic-imide amidohydrolase (decyclicizing)" EXACT [EC:3.5.2.16] synonym: "cyclic-imide amidohydrolase (decyclizing)" EXACT [EC:3.5.2.16] synonym: "imidase activity" BROAD [EC:3.5.2.16] xref: EC:3.5.2.16 xref: GO:0050539 xref: MetaCyc:3.5.2.16-RXN is_a: CCO:F0003381 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Term] id: CCO:F0007874 name: 2-aminomuconate deaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-aminomuconate + H2O = 4-oxalocrotonate + NH3." [EC:3.5.99.5, MetaCyc:3.5.99.5-RXN] subset: gosubset_prok synonym: "2-aminomuconate aminohydrolase activity" EXACT [EC:3.5.99.5] xref: EC:3.5.99.5 xref: GO:0050540 xref: MetaCyc:3.5.99.5-RXN is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is_a: CCO:F0004140 ! deaminase activity [Term] id: CCO:F0007875 name: beta,beta-carotene-9',10'-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone." [PMID:11278918] synonym: "b,b-carotene-9',10'-dioxygenase activity" EXACT [] xref: GO:0050541 is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0007876 name: icosanoid binding namespace: molecular_function def: "Interacting selectively with icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "eicosanoid binding" EXACT [] xref: GO:0050542 is_a: CCO:F0001642 ! fatty acid binding [Term] id: CCO:F0007877 name: icosatetraenoic acid binding namespace: molecular_function def: "Interacting selectively with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "eicosatetraenoic acid binding" EXACT [] xref: GO:0050543 is_a: CCO:F0007876 ! icosanoid binding [Term] id: CCO:F0007878 name: arachidonic acid binding namespace: molecular_function def: "Interacting selectively with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer." [GOC:ai] synonym: "arachidonate binding" EXACT [] xref: GO:0050544 is_a: CCO:F0007877 ! icosatetraenoic acid binding [Term] id: CCO:F0007879 name: sulfopyruvate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 3-sulfopyruvate = 2-sulfoacetaldehyde + CO2." [EC:4.1.1.79, MetaCyc:4.1.1.79-RXN] subset: gosubset_prok synonym: "sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)" EXACT [EC:4.1.1.79] synonym: "sulfopyruvate carboxy-lyase activity" EXACT [EC:4.1.1.79] synonym: "sulphopyruvate decarboxylase activity" EXACT [] xref: EC:4.1.1.79 xref: GO:0050545 xref: MetaCyc:R231-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007880 name: 4-hydroxyphenylpyruvate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxyphenylpyruvate = 4-hydroxyphenylacetaldehyde + CO2." [EC:4.1.1.80, MetaCyc:4.1.1.80-RXN] synonym: "4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming)" EXACT [EC:4.1.1.80] synonym: "4-hydroxyphenylpyruvate carboxy-lyase activity" EXACT [EC:4.1.1.80] xref: EC:4.1.1.80 xref: GO:0050546 xref: MetaCyc:4.1.1.80-RXN is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007881 name: vanillin synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA = vanillin + acetyl-CoA." [EC:4.1.2.41, MetaCyc:4.1.2.41-RXN] synonym: "3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.2.41] synonym: "3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase (acetyl-CoA-forming)" EXACT [EC:4.1.2.41] xref: EC:4.1.2.41 xref: GO:0050547 xref: MetaCyc:4.1.2.41-RXN is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0007882 name: trans-feruloyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA." [EC:4.2.1.101, MetaCyc:4.2.1.101-RXN] synonym: "4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming)" EXACT [EC:4.2.1.101] synonym: "trans-feruloyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.101] xref: EC:4.2.1.101 xref: GO:0050548 xref: MetaCyc:4.2.1.101-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007883 name: cyclohexyl-isocyanide hydratase activity namespace: molecular_function def: "Catalysis of the reaction: N-cyclohexylformamide = cyclohexyl isocyanide + H2O." [EC:4.2.1.103, MetaCyc:4.2.1.103-RXN] subset: gosubset_prok synonym: "isonitrile hydratase activity" EXACT [EC:4.2.1.103] synonym: "N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)" EXACT [EC:4.2.1.103] synonym: "N-cyclohexylformamide hydro-lyase activity" EXACT [EC:4.2.1.103] xref: EC:4.2.1.103 xref: GO:0050549 xref: MetaCyc:4.2.1.103-RXN xref: UM-BBD_enzymeID:e0638 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0007884 name: pinene synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate." [EC:4.2.3.14, MetaCyc:4.2.3.14-RXN] synonym: "(-)-(1S,5S)-pinene synthase activity" EXACT [EC:4.2.3.14] synonym: "beta-geraniolene synthase activity" EXACT [EC:4.2.3.14] synonym: "geranyl-diphosphate diphosphate-lyase (cyclizing, pinene-forming)" EXACT [EC:4.2.3.14] synonym: "geranyldiphosphate diphosphate lyase (pinene forming)" EXACT [EC:4.2.3.14] xref: EC:4.2.3.14 xref: GO:0050550 xref: MetaCyc:4.2.3.14-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007885 name: myrcene synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate = myrcene + diphosphate." [EC:4.2.3.15, MetaCyc:4.2.3.15-RXN] synonym: "geranyl-diphosphate diphosphate-lyase (myrcene-forming) activity" EXACT [] xref: EC:4.2.3.15 xref: GO:0050551 xref: MetaCyc:RXN-5110 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007887 name: taxadiene synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranylgeranyl diphosphate = taxa-4,11-diene + diphosphate." [EC:4.2.3.17, MetaCyc:4.2.3.17-RXN] synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming)" EXACT [EC:4.2.3.17] synonym: "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene-forming)" EXACT [EC:4.2.3.17] synonym: "taxa-4(5),11(12)-diene synthase activity" EXACT [EC:4.2.3.17] xref: EC:4.2.3.17 xref: GO:0050553 xref: MetaCyc:4.2.3.17-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007888 name: abietadiene synthase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate." [EC:4.2.3.18, MetaCyc:4.2.3.18-RXN] synonym: "(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)" EXACT [EC:4.2.3.18] synonym: "abietadiene cyclase activity" EXACT [EC:4.2.3.18] synonym: "copalyl-diphosphate diphosphate-lyase (cyclizing)" EXACT [EC:4.2.3.18] xref: EC:4.2.3.18 xref: GO:0050554 xref: MetaCyc:4.2.3.18-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0007889 name: 2-hydroxypropyl-CoM lyase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-[or (S)-]2-hydroxypropyl-CoM = H-S-CoM + (R)-[or (S)-]1,2-epoxypropane." [EC:4.2.99.19, MetaCyc:4.2.99.19-RXN] subset: gosubset_prok synonym: "(R)-2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (cyclizing; epoxyalkane-ring-forming)" EXACT [EC:4.4.1.23] synonym: "(R)-[or (S)-]2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)" EXACT [EC:4.4.1.23] synonym: "2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)" EXACT [EC:4.4.1.23] synonym: "coenzyme M-epoxyalkane ligase activity" EXACT [EC:4.4.1.23] synonym: "EaCoMT activity" EXACT [EC:4.4.1.23] synonym: "epoxyalkane:2-mercaptoethanesulfonate transferase activity" EXACT [EC:4.4.1.23] synonym: "epoxyalkane:coenzyme M transferase activity" EXACT [EC:4.4.1.23] synonym: "epoxyalkane:CoM transferase activity" EXACT [EC:4.4.1.23] synonym: "epoxyalkyl:CoM transferase activity" EXACT [EC:4.4.1.23] synonym: "epoxypropane:coenzyme M transferase activity" EXACT [EC:4.4.1.23] synonym: "epoxypropyl:CoM transferase activity" EXACT [EC:4.4.1.23] xref: EC:4.4.1.23 xref: GO:0050555 xref: MetaCyc:4.2.99.19-RXN xref: UM-BBD_enzymeID:e0538 is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0007890 name: deacetylisoipecoside synthase activity namespace: molecular_function def: "Catalysis of the reaction: dopamine + secologanin = deacetylisoipecoside + H2O." [EC:4.3.3.3, MetaCyc:4.3.3.3-RXN] synonym: "deacetylisoipecoside dopamine-lyase (secologanin-forming)" EXACT [EC:4.3.3.3] synonym: "deacetylisoipecoside dopamine-lyase activity" EXACT [EC:4.3.3.3] xref: EC:4.3.3.3 xref: GO:0050556 xref: MetaCyc:4.3.3.3-RXN is_a: CCO:F0003408 ! amine-lyase activity [Term] id: CCO:F0007891 name: deacetylipecoside synthase activity namespace: molecular_function def: "Catalysis of the reaction: dopamine + secologanin = deacetylipecoside + H2O." [EC:4.3.3.4, MetaCyc:4.3.3.4-RXN] synonym: "deacetylipecoside dopamine-lyase (secologanin-forming)" EXACT [EC:4.3.3.4] synonym: "deacetylipecoside dopamine-lyase activity" EXACT [EC:4.3.3.4] xref: EC:4.3.3.4 xref: GO:0050557 xref: MetaCyc:4.3.3.4-RXN is_a: CCO:F0003408 ! amine-lyase activity [Term] id: CCO:F0007892 name: maltose epimerase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-maltose = beta-maltose." [EC:5.1.3.21, MetaCyc:5.1.3.21-RXN] synonym: "maltose 1-epimerase activity" EXACT [EC:5.1.3.21] xref: EC:5.1.3.21 xref: GO:0050558 xref: MetaCyc:5.1.3.21-RXN is_a: CCO:F0003420 ! racemase and epimerase activity, acting on carbohydrates and derivatives [Term] id: CCO:F0007893 name: copalyl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranylgeranyl diphosphate = (+)-copalyl diphosphate." [EC:5.5.1.12, MetaCyc:5.5.1.12-RXN] synonym: "(+)-copalyl-diphosphate lyase (decyclizing)" EXACT [EC:5.5.1.12] synonym: "diterpene cyclase activity" BROAD [] xref: EC:5.5.1.12 xref: GO:0050559 xref: MetaCyc:5.5.1.12-RXN is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0007894 name: aspartate-tRNA(Asn) ligase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + pyrophosphate + AMP." [EC:6.1.1.23, MetaCyc:6.1.1.23-RXN] synonym: "aspartate-tRNAAsn ligase activity" EXACT [] synonym: "L-aspartate:tRNAAsx ligase (AMP-forming)" EXACT [EC:6.1.1.23] synonym: "nondiscriminating aspartyl-tRNA synthetase activity" RELATED [EC:6.1.1.23] xref: EC:6.1.1.23 xref: GO:0050560 xref: MetaCyc:6.1.1.23-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0007895 name: glutamate-tRNA(Gln) ligase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + pyrophosphate + AMP." [EC:6.1.1.24, MetaCyc:6.1.1.24-RXN] synonym: "glutamate-tRNAGln ligase activity" EXACT [] synonym: "L-glutamate:tRNAGlx ligase (AMP-forming)" EXACT [EC:6.1.1.24] synonym: "nondiscriminating glutamyl-tRNA synthetase activity" RELATED [EC:6.1.1.24] xref: EC:6.1.1.24 xref: GO:0050561 xref: MetaCyc:6.1.1.24-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0007896 name: lysine-tRNA(Pyl) ligase activity namespace: molecular_function def: "Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + pyrophosphate + AMP." [EC:6.1.1.25, MetaCyc:6.1.1.25-RXN] synonym: "L-lysine:tRNAPyl ligase (AMP-forming)" EXACT [EC:6.1.1.25] synonym: "lysine-tRNAPyl ligase activity" EXACT [] xref: EC:6.1.1.25 xref: GO:0050562 xref: MetaCyc:6.1.1.25-RXN is_a: CCO:F0001170 ! aminoacyl-tRNA ligase activity [Term] id: CCO:F0007897 name: trans-feruloyl-CoA synthase activity namespace: molecular_function def: "Catalysis of the reaction: ferulic acid + CoASH + ATP = trans-feruloyl-CoA + products of ATP breakdown." [EC:6.2.1.34, MetaCyc:6.2.1.34-RXN] synonym: "trans-ferulate:CoASH ligase (ATP-hydrolysing)" EXACT [EC:6.2.1.34] synonym: "trans-feruloyl-CoA synthetase activity" EXACT [EC:6.2.1.34] xref: EC:6.2.1.34 xref: GO:0050563 xref: MetaCyc:6.2.1.34-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0007898 name: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-aminohexanedioate + L-cysteine + L-valine + 3 ATP + H2O = N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate." [EC:6.3.2.26, MetaCyc:6.3.2.26-RXN] subset: gosubset_prok synonym: "ACV synthetase activity" BROAD [EC:6.3.2.26] synonym: "L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting)" EXACT [EC:6.3.2.26] synonym: "L-alpha-aminoadipyl-cysteinyl-valine synthetase activity" EXACT [EC:6.3.2.26] synonym: "L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase activity" EXACT [EC:6.3.2.26] xref: EC:6.3.2.26 xref: GO:0050564 xref: MetaCyc:6.3.2.26-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0007899 name: aerobactin synthase activity namespace: molecular_function def: "Catalysis of the reaction: 4 ATP + citrate + N6-acetyl-N6-hydroxylysine = 4 ADP + 4 phosphate + aerobactin." [EC:6.3.2.27, MetaCyc:6.3.2.27-RXN] synonym: "citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)" EXACT [EC:6.3.2.27] synonym: "citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming)" EXACT [EC:6.3.2.27] xref: EC:6.3.2.27 xref: GO:0050565 xref: MetaCyc:6.3.2.27-RXN is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0007900 name: asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP." [EC:6.3.5.6, MetaCyc:6.3.5.6-RXN] synonym: "Asp-AdT activity" EXACT [EC:6.3.5.6] synonym: "Asp-tRNA(Asn) amidotransferase activity" EXACT [EC:6.3.5.6] synonym: "Asp-tRNAAsn amidotransferase activity" EXACT [EC:6.3.5.6] synonym: "Asp-tRNAAsn:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.6] synonym: "asparaginyl-tRNA synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.6] synonym: "aspartyl-tRNA(Asn) amidotransferase activity" EXACT [EC:6.3.5.6] synonym: "aspartyl-tRNAAsn amidotransferase activity" EXACT [EC:6.3.5.6] synonym: "aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.6] xref: EC:6.3.5.6 xref: GO:0050566 xref: MetaCyc:6.3.5.6-RXN is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0007901 name: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP." [EC:6.3.5.7, MetaCyc:6.3.5.7-RXN] subset: gosubset_prok synonym: "Glu-AdT activity" EXACT [EC:6.3.5.-] synonym: "glu-tRNA(gln) amidotransferase activity" EXACT [EC:6.3.5.-] synonym: "Glu-tRNA(Gln) amidotransferase activity" EXACT [EC:6.3.5.-] synonym: "Glu-tRNAGln amidotransferase activity" EXACT [EC:6.3.5.7] synonym: "Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.7] synonym: "glutaminyl-tRNA synthase (glutamine-hydrolysing)" EXACT [EC:6.3.5.7] synonym: "glutamyl-tRNA(Gln) amidotransferase activity" EXACT [EC:6.3.5.-] synonym: "glutamyl-tRNAGln amidotransferase activity" EXACT [EC:6.3.5.7] synonym: "glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.7] xref: EC:6.3.5.- xref: EC:6.3.5.7 xref: GO:0008264 xref: GO:0017068 xref: GO:0050567 xref: MetaCyc:6.3.5.7-RXN is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0007902 name: protein-glutamine glutaminase activity namespace: molecular_function def: "Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3." [EC:3.5.1.44, MetaCyc:CHEBDEAMID-RXN] synonym: "destabilase activity" EXACT [EC:3.5.1.44] synonym: "glutaminyl-peptide glutaminase activity" EXACT [EC:3.5.1.44] synonym: "glutaminylpeptide glutaminase activity" EXACT [EC:3.5.1.44] synonym: "peptidoglutaminase II activity" RELATED [EC:3.5.1.44] synonym: "peptidylglutaminase II" RELATED [EC:3.5.1.44] synonym: "protein-L-glutamine amidohydrolase activity" EXACT [EC:3.5.1.44] xref: EC:3.5.1.44 xref: GO:0050568 xref: MetaCyc:CHEBDEAMID-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0007903 name: glycolaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: glycolaldehyde + NAD+ + H2O = glycolate + NADH + H+." [EC:1.1.1.262, EC:1.2.1.21, MetaCyc:1.1.1.262-RXN, MetaCyc:GLYCOLALD-DEHYDROG-RXN] subset: gosubset_prok synonym: "glycol aldehyde dehydrogenase activity" EXACT [EC:1.2.1.21] synonym: "glycolaldehyde:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.21] xref: EC:1.2.1.21 xref: GO:0050569 xref: MetaCyc:GLYCOLALD-DEHYDROG-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007904 name: 4-hydroxythreonine-4-phosphate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+." [EC:1.1.1.262, MetaCyc:1.1.1.262-RXN] subset: gosubset_prok synonym: "4-(phosphohydroxy)-L-threonine dehydrogenase activity" EXACT [EC:1.1.1.262] synonym: "4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.262] synonym: "L-threonine 4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.262] synonym: "NAD(+)-dependent threonine 4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.262] synonym: "NAD+-dependent threonine 4-phosphate dehydrogenase activity" EXACT [EC:1.1.1.262] synonym: "PdxA" RELATED [EC:1.1.1.262] xref: EC:1.1.1.262 xref: GO:0050570 xref: MetaCyc:1.1.1.262-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007905 name: 1,5-anhydro-D-fructose reductase activity namespace: molecular_function def: "Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP+ = 1,5-anhydro-D-fructose + NADPH + H+." [EC:1.1.1.263, MetaCyc:1.1.1.263-RXN] synonym: "1,5-anhydro-D-glucitol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.263] synonym: "AF reductase activity" EXACT [EC:1.1.1.263] xref: EC:1.1.1.263 xref: GO:0050571 xref: MetaCyc:1.1.1.263-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007906 name: L-idonate 5-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+." [EC:1.1.1.264, MetaCyc:1.1.1.264-RXN] subset: gosubset_prok synonym: "L-idonate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.264] xref: EC:1.1.1.264 xref: GO:0050572 xref: MetaCyc:1.1.1.264-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007907 name: dTDP-4-dehydro-6-deoxyglucose reductase activity namespace: molecular_function def: "Catalysis of the reaction: dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+." [EC:1.1.1.266, MetaCyc:1.1.1.266-RXN] synonym: "dTDP-4-keto-6-deoxyglucose reductase activity" EXACT [EC:1.1.1.266] synonym: "dTDP-D-fucose:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.266] xref: EC:1.1.1.266 xref: GO:0050573 xref: MetaCyc:1.1.1.266-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007908 name: 2-(R)-hydroxypropyl-CoM dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-(R)-hydroxypropyl-CoM + NAD+ = 2-oxopropyl-CoM + NADH + H+." [EC:1.1.1.268, MetaCyc:1.1.1.268-RXN] subset: gosubset_prok synonym: "2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase activity" EXACT [EC:1.1.1.268] synonym: "2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.268] xref: EC:1.1.1.268 xref: GO:0050574 xref: MetaCyc:1.1.1.268-RXN xref: UM-BBD_enzymeID:e0539 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007909 name: 2-(S)-hydroxypropyl-CoM dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-(S)-hydroxypropyl-CoM + NAD+ = 2-oxopropyl-CoM + NADH + H+." [EC:1.1.1.269, MetaCyc:1.1.1.269-RXN] subset: gosubset_prok synonym: "2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase activity" EXACT [EC:1.1.1.269] synonym: "2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.269] xref: EC:1.1.1.269 xref: GO:0050575 xref: MetaCyc:1.1.1.269-RXN xref: UM-BBD_enzymeID:e0540 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007910 name: 3-keto-steroid reductase activity namespace: molecular_function def: "Catalysis of the reaction: 4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NADP+ = 4-alpha-methyl-5-alpha-cholest-7-en-3-one + NADPH + H+." [EC:1.1.1.270, MetaCyc:1.1.1.270-RXN] synonym: "3-KSR activity" EXACT [EC:1.1.1.270] synonym: "3beta-hydroxy-steroid:NADP+ 3-oxidoreductase" RELATED [EC:1.1.1.270] xref: EC:1.1.1.270 xref: GO:0050576 xref: MetaCyc:1.1.1.270-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007911 name: GDP-L-fucose synthase activity namespace: molecular_function def: "Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+." [EC:1.1.1.271, MetaCyc:1.1.1.271-RXN] subset: gosubset_prok synonym: "GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase activity" EXACT [EC:1.1.1.271] synonym: "GDP-fucose synthetase activity" EXACT [EC:1.1.1.271] synonym: "GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)" EXACT [EC:1.1.1.271] xref: EC:1.1.1.271 xref: GO:0050577 xref: MetaCyc:1.1.1.271-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007913 name: vellosimine dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 10-deoxysarpagine + NADP+ = vellosimine + NADPH + H+." [EC:1.1.1.273, MetaCyc:1.1.1.273-RXN] synonym: "10-deoxysarpagine:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.273] xref: EC:1.1.1.273 xref: GO:0050579 xref: MetaCyc:1.1.1.273-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007914 name: 2,5-didehydrogluconate reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+." [EC:1.1.1.274, MetaCyc:1.1.1.274-RXN] subset: gosubset_prok synonym: "2,5-diketo-D-gluconate reductase activity" EXACT [EC:1.1.1.274] synonym: "2-dehydro-D-gluconate:NADP+ 2-oxidoreductase activity" EXACT [EC:1.1.1.274] synonym: "YqhE reductase" RELATED [EC:1.1.1.274] xref: EC:1.1.1.274 xref: GO:0050580 xref: MetaCyc:1.1.1.274-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007915 name: D-mannitol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: mannitol + O2 = mannose + H2O2." [EC:1.1.3.40, MetaCyc:1.1.3.40-RXN] synonym: "D-arabinitol oxidase activity" RELATED [EC:1.1.3.40] synonym: "D-arabitol oxidase activity" EXACT [EC:1.1.3.40] synonym: "mannitol oxidase activity" EXACT [EC:1.1.3.40] synonym: "mannitol:oxygen oxidoreductase (cyclizing)" EXACT [EC:1.1.3.40] xref: EC:1.1.3.40 xref: GO:0050581 xref: MetaCyc:1.1.3.40-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007916 name: xylitol oxidase activity namespace: molecular_function def: "Catalysis of the reaction: xylitol + O2 = xylose + H2O2." [EC:1.1.3.41, MetaCyc:1.1.3.41-RXN] subset: gosubset_prok synonym: "xylitol:oxygen oxidoreductase activity" EXACT [EC:1.1.3.41] xref: EC:1.1.3.41 xref: GO:0050582 xref: MetaCyc:1.1.3.41-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0007917 name: hydrogen dehydrogenase (NADP+) activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + H2 = NADPH + H+." [EC:1.12.1.3, MetaCyc:1.12.1.3-RXN] synonym: "hydrogen:NADP+ oxidoreductase activity" EXACT [EC:1.12.1.3] synonym: "NADP-linked hydrogenase activity" RELATED [EC:1.12.1.3] synonym: "NADP-reducing hydrogenase activity" RELATED [EC:1.12.1.3] xref: EC:1.12.1.3 xref: GO:0050583 xref: MetaCyc:1.12.1.3-RXN is_a: CCO:F0003282 ! oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor [Term] id: CCO:F0007918 name: linoleate 11-lipoxygenase activity namespace: molecular_function def: "Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(11S)-11-hydroperoxyoctadeca-9,12-dienoate." [EC:1.13.11.45, MetaCyc:1.13.11.45-RXN] synonym: "linoleate dioxygenase activity" EXACT [EC:1.13.11.45] synonym: "linoleate:oxygen 11S-oxidoreductase activity" EXACT [EC:1.13.11.45] synonym: "manganese lipoxygenase activity" EXACT [EC:1.13.11.45] xref: EC:1.13.11.45 xref: GO:0050584 xref: MetaCyc:1.13.11.45-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007919 name: 4-hydroxymandelate synthase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2." [EC:1.13.11.46, MetaCyc:1.13.11.46-RXN] synonym: "4-hydroxyphenylpyruvate dioxygenase II activity" NARROW [EC:1.13.11.46] synonym: "4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)" BROAD [EC:1.13.11.46] xref: EC:1.13.11.46 xref: GO:0050585 xref: MetaCyc:1.13.11.46-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007920 name: 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-2-methyl-1H-quinolin-4-one + O2 = N-acetylanthranilate + CO." [EC:1.13.11.48, MetaCyc:1.13.11.48-RXN] subset: gosubset_prok synonym: "(1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity" EXACT [EC:1.13.11.48] synonym: "1H-3-hydroxy-4-oxo quinaldine 2,4-dioxygenase activity" EXACT [] synonym: "1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity" EXACT [] synonym: "3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)" EXACT [EC:1.13.11.48] synonym: "3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase activity" EXACT [] xref: EC:1.13.11.48 xref: GO:0050586 xref: MetaCyc:1.13.11.48-RXN is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007921 name: chlorite O2-lyase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + Cl- = chlorite." [EC:1.13.11.49, MetaCyc:1.13.11.49-RXN] synonym: "chloride:oxygen oxidoreductase activity" EXACT [EC:1.13.11.49] synonym: "chlorite dismutase activity" EXACT [EC:1.13.11.49] xref: EC:1.13.11.49 xref: GO:0030065 xref: GO:0050587 xref: MetaCyc:1.13.11.49-RXN xref: UM-BBD_enzymeID:e0610 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0007922 name: apo-beta-carotenoid-14',13'-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 8'-apo-beta-carotenol + O2 = 14'-apo-beta-carotenal + H2O." [EC:1.13.12.12, MetaCyc:1.13.12.12-RXN] synonym: "8'-apo-beta-carotenol:O2 oxidoreductase activity" EXACT [EC:1.13.12.12] synonym: "apo-b-carotenoid-14',13'-dioxygenase activity" EXACT [] xref: EC:1.13.12.12 xref: GO:0050588 xref: MetaCyc:1.13.12.12-RXN is_a: CCO:F0003287 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) [Term] id: CCO:F0007923 name: leucocyanidin oxygenase activity namespace: molecular_function def: "Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O." [EC:1.14.11.19, MetaCyc:1.14.11.19-RXN] synonym: "anthocyanidin synthase activity" RELATED [EC:1.14.11.19] synonym: "leucoanthocyanidin dioxygenase activity" EXACT [EC:1.14.11.19] synonym: "leucoanthocyanidin hydroxylase" RELATED [EC:1.14.11.19] synonym: "leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.19] xref: EC:1.14.11.19 xref: GO:0045432 xref: GO:0050589 xref: MetaCyc:RXN-602 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors is_a: CCO:F0008070 ! dioxygenase activity [Term] id: CCO:F0007924 name: desacetoxyvindoline 4-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2." [EC:1.14.11.20, MetaCyc:1.14.11.20-RXN] synonym: "D17H activity" RELATED [EC:1.14.11.20] synonym: "deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)" EXACT [EC:1.14.11.20] synonym: "desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity" EXACT [EC:1.14.11.20] synonym: "desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)" EXACT [EC:1.14.11.20] synonym: "desacetoxyvindoline-4-hydroxylase activity" EXACT [EC:1.14.11.20] synonym: "desacetyoxyvindoline-17-hydroxylase activity" EXACT [EC:1.14.11.20] xref: EC:1.14.11.20 xref: GO:0050590 xref: MetaCyc:1.14.11.20-RXN is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [Term] id: CCO:F0007925 name: quinine 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: quinine + NADPH + H+ + O2 = 3-hydroxyquinine + NADP+ + H2O." [EC:1.14.13.67, MetaCyc:1.14.13.67-RXN] synonym: "nifedipine oxidase activity" EXACT [EC:1.14.13.67] synonym: "quinine 3-hydroxylase activity" EXACT [] synonym: "quinine,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.67] xref: EC:1.14.13.67 xref: GO:0050591 xref: MetaCyc:1.14.13.67-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007926 name: 4-hydroxyphenylacetaldehyde oxime monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxyphenylacetaldehyde oxime + NADPH + H+ + O2 = 4-hydroxymandelonitrile + NADP+ + 2 H2O." [EC:1.14.13.68, MetaCyc:1.14.13.68-RXN] synonym: "(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.68] synonym: "4-hydroxybenzeneacetaldehyde oxime monooxygenase activity" EXACT [EC:1.14.13.68] synonym: "4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity" EXACT [EC:1.14.13.68] synonym: "CYP71E1 activity" NARROW [EC:1.14.13.68] synonym: "cytochrome P450-II-dependent monooxygenase activity" NARROW [EC:1.14.13.68] synonym: "cytochrome P450II-dependent monooxygenase activity" EXACT [EC:1.14.13.68] synonym: "NADPH-cytochrome P450 reductase (CYP71E1)" EXACT [EC:1.14.13.68] xref: EC:1.14.13.68 xref: GO:0050592 xref: MetaCyc:1.14.13.68-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007927 name: N-methylcoclaurine 3'-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-N-methylcoclaurine + NADPH + H+ + O2 = (S)-3'-hydroxy-N-methylcoclaurine + NADP+ + H2O." [EC:1.14.13.71, MetaCyc:1.14.13.71-RXN] synonym: "(S)-N-methylcoclaurine 3'-hydroxylase activity" EXACT [EC:1.14.13.71] synonym: "(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating)" EXACT [EC:1.14.13.71] synonym: "cytochrome P450 80B1 activity" EXACT [EC:1.14.13.71] synonym: "N-methylcoclaurine 3'-hydroxylase activity" EXACT [] xref: EC:1.14.13.71 xref: GO:0050593 xref: MetaCyc:1.14.13.71-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007928 name: tabersonine 16-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: tabersonine + NADPH + H+ + O2 = 16-hydroxytabersonine + NADP+ + H2O." [EC:1.14.13.73, MetaCyc:1.14.13.73-RXN] synonym: "tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)" EXACT [EC:1.14.13.73] xref: EC:1.14.13.73 xref: GO:0050594 xref: MetaCyc:1.14.13.73-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007929 name: 7-deoxyloganin 7-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O." [EC:1.14.13.74, MetaCyc:1.14.13.74-RXN] synonym: "7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)" EXACT [EC:1.14.13.74] xref: EC:1.14.13.74 xref: GO:0050595 xref: MetaCyc:1.14.13.74-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007930 name: vinorine hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: vinorine + NADPH + H+ + O2 = vomilenine + NADP+ + H2O." [EC:1.14.13.75, MetaCyc:1.14.13.75-RXN] synonym: "vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating)" EXACT [EC:1.14.13.75] xref: EC:1.14.13.75 xref: GO:0050596 xref: MetaCyc:1.14.13.75-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007931 name: taxane 10-beta-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + taxa-4(20),11-dien-5-alpha-yl acetate = H2O + NADP+ + 10-beta-hydroxytaxa-4(20),11-dien-5-alpha-yl acetate." [EC:1.14.13.76, MetaCyc:1.14.13.76-RXN] synonym: "5-alpha-taxadienol-10-beta-hydroxylase activity" EXACT [EC:1.14.13.76] synonym: "taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)" EXACT [EC:1.14.13.76] synonym: "taxane 10b-hydroxylase activity" EXACT [] synonym: "taxane 10beta-hydroxylase activity" EXACT [EC:1.14.13.76] xref: EC:1.14.13.76 xref: GO:0050597 xref: MetaCyc:1.14.13.76-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007932 name: taxane 13-alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + taxa-4(20),11-dien-5-alpha-ol = H2O + NADP+ + taxa-4(20),11-dien-5-alpha,13-alpha-diol." [EC:1.14.13.77, MetaCyc:1.14.13.77-RXN] synonym: "taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)" EXACT [EC:1.14.13.77] synonym: "taxane 13a-hydroxylase activity" EXACT [] synonym: "taxane 13alpha-hydroxylase activity" EXACT [EC:1.14.13.77] xref: EC:1.14.13.77 xref: GO:0050598 xref: MetaCyc:1.14.13.77-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0007933 name: deacetoxycephalosporin-C synthase activity namespace: molecular_function def: "Catalysis of the reaction: penicillin-N + 2-oxoglutarate + O2 = deacetoxycephalosporin C + succinate + CO2 + H2O." [EC:1.14.20.1, MetaCyc:1.14.20.1-RXN] subset: gosubset_prok synonym: "DAOC synthase activity" EXACT [EC:1.14.20.1] synonym: "DAOCS activity" EXACT [EC:1.14.20.1] synonym: "penicillin N expandase activity" RELATED [EC:1.14.20.1] synonym: "penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)" EXACT [EC:1.14.20.1] xref: EC:1.14.20.1 xref: GO:0050599 xref: MetaCyc:1.14.20.1-RXN is_a: CCO:F0007835 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated [Term] id: CCO:F0007934 name: myristoyl-CoA 11-(E) desaturase activity namespace: molecular_function def: "Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O." [EC:1.14.99.31, MetaCyc:1.14.99.31-RXN] synonym: "n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating]" RELATED [EC:1.14.99.31] synonym: "n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]" RELATED [EC:1.14.99.31] xref: EC:1.14.99.31 xref: GO:0050600 xref: MetaCyc:1.14.99.31-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007935 name: myristoyl-CoA 11-(Z) desaturase activity namespace: molecular_function def: "Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O." [EC:1.14.99.32, MetaCyc:1.14.99.32-RXN] synonym: "n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(Z) desaturating]" RELATED [EC:1.14.99.32] synonym: "n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]" RELATED [EC:1.14.99.32] xref: EC:1.14.99.32 xref: GO:0050601 xref: MetaCyc:1.14.99.32-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007936 name: monoprenyl isoflavone epoxidase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives." [EC:1.14.99.34, MetaCyc:1.14.99.34-RXN] synonym: "7-O-methylluteone,NADPH:O2 oxidoreductase activity" EXACT [EC:1.14.99.34] synonym: "7-O-methylluteone:O2 oxidoreductase activity" EXACT [EC:1.14.99.34] synonym: "monoprenyl isoflavone monooxygenase activity" EXACT [EC:1.14.99.34] xref: EC:1.14.99.34 xref: GO:0050602 xref: MetaCyc:1.14.99.34-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007937 name: thiophene-2-carbonyl-CoA monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O." [EC:1.14.99.35, MetaCyc:1.14.99.35-RXN] synonym: "thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity" EXACT [EC:1.14.99.35] synonym: "thiophene-2-carboxyl-CoA dehydrogenase activity" EXACT [EC:1.14.99.35] synonym: "thiophene-2-carboxyl-CoA hydroxylase activity" EXACT [EC:1.14.99.35] synonym: "thiophene-2-carboxyl-CoA monooxygenase activity" EXACT [EC:1.14.99.35] xref: EC:1.14.99.35 xref: GO:0050603 xref: MetaCyc:1.14.99.35-RXN xref: UM-BBD_enzymeID:e0775 is_a: CCO:F0000894 ! monooxygenase activity is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007938 name: taxadiene 5-alpha-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + donor-H2 + taxa-4,11-diene = H2O + acceptor + taxa-4(20),11-dien-5-alpha-ol." [EC:1.14.99.37, MetaCyc:1.14.99.37-RXN] synonym: "taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating)" EXACT [EC:1.14.99.37] synonym: "taxadiene 5a-hydroxylase activity" EXACT [] synonym: "taxadiene 5alpha-hydroxylase activity" EXACT [EC:1.14.99.37] xref: EC:1.14.99.37 xref: GO:0050604 xref: MetaCyc:1.14.99.37-RXN is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0007939 name: superoxide reductase activity namespace: molecular_function def: "Catalysis of the reaction: O2(-) + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin." [EC:1.15.1.2, MetaCyc:1.15.1.2-RXN] subset: gosubset_prok synonym: "desulfoferrodoxin activity" RELATED [EC:1.15.1.2] synonym: "neelaredoxin activity" RELATED [EC:1.15.1.2] synonym: "rubredoxin:superoxide oxidoreductase activity" EXACT [EC:1.15.1.2] xref: EC:1.15.1.2 xref: GO:0050605 xref: MetaCyc:1.15.1.2-RXN is_a: CCO:F0003303 ! oxidoreductase activity, acting on superoxide radicals as acceptor [Term] id: CCO:F0007940 name: 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + NADP+ = 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH + H+." [EC:1.2.1.45, MetaCyc:1.2.1.45-RXN] synonym: "2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.45] synonym: "4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP+ 6-oxidoreductase activity" EXACT [EC:1.2.1.45] synonym: "4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP+ oxidoreductase activity" EXACT [EC:1.2.1.45] synonym: "alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity" EXACT [EC:1.2.1.45] xref: EC:1.2.1.45 xref: GO:0050606 xref: MetaCyc:1.2.1.45-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007941 name: mycothiol-dependent formaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+." [EC:1.2.1.66, MetaCyc:1.2.1.66-RXN] subset: gosubset_prok synonym: "formaldehyde:NAD+ oxidoreductase (mycothiol-formylating)" EXACT [EC:1.2.1.66] synonym: "NAD/factor-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.2.1.66] xref: EC:1.2.1.66 xref: GO:0050607 xref: MetaCyc:1.2.1.66-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007942 name: vanillin dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: vanillin + NAD+ + H2O = vanillate + NADH + H+." [EC:1.2.1.67, MetaCyc:1.2.1.67-RXN] synonym: "vanillin:NAD+ oxidoreductase activity" EXACT [EC:1.2.1.67] xref: EC:1.2.1.67 xref: GO:0050608 xref: MetaCyc:1.2.1.67-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007943 name: phosphonate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: phosphonate + NAD+ + H2O = phosphate + NADH + H+." [EC:1.20.1.1, MetaCyc:1.20.1.1-RXN] subset: gosubset_prok synonym: "NAD-dependent phosphite dehydrogenas activity" EXACT [EC:1.20.1.1] synonym: "NAD:phosphite oxidoreductase activity" EXACT [EC:1.20.1.1] synonym: "phosphite dehydrogenase activity" EXACT [EC:1.20.1.1] synonym: "phosphonate:NAD+ oxidoreductase activity" EXACT [EC:1.20.1.1] xref: EC:1.20.1.1 xref: GO:0050609 xref: MetaCyc:1.20.1.1-RXN xref: UM-BBD_enzymeID:e0658 is_a: CCO:F0007836 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor [Term] id: CCO:F0007944 name: methylarsonate reductase activity namespace: molecular_function def: "Catalysis of the reaction: reduced glutathione + methylarsonate = oxidized glutathione + methylarsonite." [EC:1.20.4.2, MetaCyc:1.20.4.2-RXN] synonym: "gluthathione:methylarsonate oxidoreductase activity" EXACT [EC:1.20.4.2] synonym: "MMA(V) reductase activity" EXACT [EC:1.20.4.2] xref: EC:1.20.4.2 xref: GO:0050610 xref: MetaCyc:1.20.4.2-RXN xref: UM-BBD_enzymeID:e0528 is_a: CCO:F0004501 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulfide as acceptor [Term] id: CCO:F0007945 name: arsenate reductase (azurin) activity namespace: molecular_function def: "Catalysis of the reaction: azurin(ox) + H2O + arsenite = azurin(red) + arsenate." [EC:1.20.98.1, MetaCyc:1.20.98.1-RXN] subset: gosubset_prok synonym: "arsenite:azurin oxidoreductase activity" EXACT [EC:1.20.98.1] xref: EC:1.20.98.1 xref: GO:0050611 xref: MetaCyc:1.20.98.1-RXN is_a: CCO:F0007857 ! oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors [Term] id: CCO:F0007946 name: arsenate reductase (donor) activity namespace: molecular_function def: "Catalysis of the reaction: acceptor + arsenite = donor-H2 + arsenate." [EC:1.20.99.1, MetaCyc:1.20.99.1-RXN] synonym: "arsenate:(acceptor) oxidoreductase activity" EXACT [EC:1.20.99.1] synonym: "arsenate:acceptor oxidoreductase activity" EXACT [EC:1.20.99.1] xref: EC:1.20.99.1 xref: GO:0050612 xref: MetaCyc:1.20.99.1-RXN is_a: CCO:F0004500 ! oxidoreductase activity, acting on phosphorus or arsenic in donors [Term] id: CCO:F0007947 name: delta14-sterol reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol." [EC:1.3.1.70, MetaCyc:1.3.1.70-RXN] comment: Note that zymosterol is cholesta-8,24-dien-3-ol. synonym: "4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity" EXACT [EC:1.3.1.70] synonym: "C-14 sterol reductase activity" EXACT [] synonym: "D14-sterol reductase activity" EXACT [] synonym: "sterol C-14 reductase activity" EXACT [] synonym: "sterol C14-reductase activity" EXACT [EC:1.3.1.70] xref: EC:1.3.1.70 xref: GO:0000251 xref: GO:0050613 xref: MetaCyc:1.3.1.70-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007948 name: delta24-sterol reductase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol." [EC:1.3.1.72, MetaCyc:1.3.1.72-RXN] synonym: "D24-sterol reductase activity" EXACT [] synonym: "lanosterol Delta(24)-reductase activity" NARROW [EC:1.3.1.72] synonym: "lanosterol delta24-reductase activity" EXACT [EC:1.3.1.72] synonym: "sterol:NADP+ delta24-oxidoreductase activity" EXACT [EC:1.3.1.72] xref: EC:1.3.1.72 xref: GO:0050614 xref: MetaCyc:1.3.1.72-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007949 name: 1,2-dihydrovomilenine reductase activity namespace: molecular_function def: "Catalysis of the reaction: 17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + NADPH + H+." [EC:1.3.1.73, MetaCyc:1.3.1.73-RXN] synonym: "17-O-acetylnorajmaline:NADP+ oxidoreductase activity" EXACT [EC:1.3.1.73] xref: EC:1.3.1.73 xref: GO:0050615 xref: MetaCyc:1.3.1.73-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007950 name: secologanin synthase activity namespace: molecular_function def: "Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O." [EC:1.3.3.9, MetaCyc:1.3.3.9-RXN] synonym: "loganin:oxygen oxidoreductase (ring-cleaving)" EXACT [EC:1.3.3.9] xref: EC:1.3.3.9 xref: GO:0050616 xref: MetaCyc:1.3.3.9-RXN is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0007951 name: 15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin." [EC:1.3.7.2, MetaCyc:1.3.7.2-RXN] subset: gosubset_prok synonym: "PebA" RELATED [EC:1.3.7.2] xref: EC:1.3.7.2 xref: GO:0050617 xref: MetaCyc:1.3.7.2-RXN is_a: CCO:F0003237 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0007952 name: phycoerythrobilin:ferredoxin oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin." [EC:1.3.7.3, MetaCyc:1.3.7.3-RXN] subset: gosubset_prok synonym: "(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.3] synonym: "PebB" RELATED [EC:1.3.7.3] xref: EC:1.3.7.3 xref: GO:0050618 xref: MetaCyc:1.3.7.3-RXN is_a: CCO:F0003237 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0007953 name: phytochromobilin:ferredoxin oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin." [EC:1.3.7.4, MetaCyc:1.3.7.4-RXN] synonym: "(3Z)-phytochromobilin:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.4] synonym: "HY2" RELATED [EC:1.3.7.4] synonym: "P-Phi-B synthase activity" RELATED [EC:1.3.7.4] synonym: "PFB synthase activity" EXACT [EC:1.3.7.4] synonym: "phytochromobilin synthase activity" EXACT [EC:1.3.7.4] synonym: "PPhiB synthase activity" EXACT [EC:1.3.7.4] xref: EC:1.3.7.4 xref: GO:0050619 xref: MetaCyc:1.3.7.4-RXN is_a: CCO:F0003237 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0007954 name: phycocyanobilin:ferredoxin oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin." [EC:1.3.7.5, MetaCyc:1.3.7.5-RXN] subset: gosubset_prok synonym: "(3Z)-phycocyanobilin:ferredoxin oxidoreductase activity" EXACT [EC:1.3.7.5] xref: EC:1.3.7.5 xref: GO:0050620 xref: MetaCyc:1.3.7.5-RXN is_a: CCO:F0003237 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0007955 name: tryptophan alpha,beta-oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2." [EC:1.3.3.10, MetaCyc:1.4.3.17-RXN] comment: Note that this was EC:1.4.3.17. synonym: "L-tryptophan 2',3'-oxidase activity" EXACT [EC:1.3.3.10] synonym: "L-tryptophan alpha,beta-dehydrogenase activity" EXACT [EC:1.3.3.10] synonym: "L-tryptophan:oxygen alpha,beta-oxidoreductase activity" EXACT [EC:1.3.3.10] synonym: "tryptophan a,b-oxidase activity" EXACT [] xref: EC:1.3.3.10 xref: GO:0050621 xref: MetaCyc:1.4.3.17-RXN is_a: CCO:F0003235 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor [Term] id: CCO:F0007956 name: glycine dehydrogenase (cyanide-forming) activity namespace: molecular_function def: "Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2." [EC:1.4.99.5, MetaCyc:1.4.99.5-RXN] synonym: "glycine:acceptor oxidoreductase (hydrogen-cyanide-forming)" EXACT [EC:1.4.99.5] synonym: "HCN synthase activity" EXACT [EC:1.4.99.5] synonym: "hydrogen cyanide synthase activity" EXACT [EC:1.4.99.5] xref: EC:1.4.99.5 xref: GO:0050622 xref: MetaCyc:1.4.99.5-RXN is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0007957 name: berberine reductase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-canadine + 2 NADP+ = berberine + 2 NADPH + H+." [EC:1.5.1.31, MetaCyc:1.5.1.31-RXN] synonym: "(R)-canadine synthase activity" EXACT [EC:1.5.1.31] synonym: "(R)-tetrahydroberberine:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.31] xref: EC:1.5.1.31 xref: GO:0050623 xref: MetaCyc:1.5.1.31-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007958 name: vomilenine reductase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydrovomilenine + NADP+ = vomilenine + NADPH + H+." [EC:1.5.1.32, MetaCyc:1.5.1.32-RXN] synonym: "1,2-dihydrovomilenine:NADP+ oxidoreductase activity" EXACT [EC:1.5.1.32] xref: EC:1.5.1.32 xref: GO:0050624 xref: MetaCyc:1.5.1.32-RXN is_a: CCO:F0003245 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007959 name: 2-hydroxy-1,4-benzoquinone reductase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + NADH + H+ = NAD+ + 1,2,4-benzenetriol." [EC:1.6.5.7, MetaCyc:1.6.5.7-RXN] synonym: "1,2,4-trihydroxybenzene:NAD oxidoreductase activity" EXACT [EC:1.6.5.7] synonym: "1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity" EXACT [EC:1.6.5.7] synonym: "2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity" EXACT [EC:1.6.5.7] synonym: "hydroxybenzoquinone reductase activity" EXACT [EC:1.6.5.-] synonym: "NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity" EXACT [EC:1.6.5.7] xref: EC:1.6.5.- xref: EC:1.6.5.7 xref: GO:0018540 xref: GO:0050625 xref: MetaCyc:1.6.5.7-RXN xref: UM-BBD_enzymeID:e0424 is_a: CCO:F0003253 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor [Term] id: CCO:F0007960 name: trimethylamine-N-oxide reductase (cytochrome c) activity namespace: molecular_function def: "Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+ ." [EC:1.7.2.3, MetaCyc:1.7.2.3-RXN] subset: gosubset_prok synonym: "TMAO reductase activity" EXACT [EC:1.7.2.3] synonym: "TOR activity" EXACT [EC:1.7.2.3] synonym: "trimethylamine:cytochrome c oxidoreductase activity" EXACT [EC:1.7.2.3] xref: EC:1.7.2.3 xref: GO:0050626 xref: MetaCyc:1.7.2.3-RXN is_a: CCO:F0003257 ! oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor [Term] id: CCO:F0007961 name: mycothione reductase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione." [EC:1.8.1.15, MetaCyc:1.8.1.15-RXN] synonym: "mycothiol-disulfide reductase activity" EXACT [EC:1.8.1.15] synonym: "mycothiol:NAD(P)+ oxidoreductase activity" EXACT [EC:1.8.1.15] xref: EC:1.8.1.15 xref: GO:0050627 xref: MetaCyc:1.8.1.15-RXN is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007962 name: 2-oxopropyl-CoM reductase (carboxylating) activity namespace: molecular_function def: "Catalysis of the reaction: 2-mercaptoethanesulfonate + acetoacetate + NADP+ = 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+." [EC:1.8.1.5, MetaCyc:1.8.1.5-RXN] subset: gosubset_prok synonym: "2-KPCC activity" EXACT [EC:1.8.1.5] synonym: "2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating)" EXACT [EC:1.8.1.5] synonym: "NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity" EXACT [EC:1.8.1.5] synonym: "NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity" EXACT [EC:1.8.1.5] xref: EC:1.8.1.5 xref: GO:0050628 xref: MetaCyc:1.8.1.5-RXN xref: UM-BBD_enzymeID:e0541 is_a: CCO:F0003261 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor [Term] id: CCO:F0007963 name: tetrachloroethene reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor." [EC:1.97.1.8, MetaCyc:1.97.1.8-RXN] subset: gosubset_prok synonym: "acceptor:trichloroethene oxidoreductase (chlorinating)" EXACT [EC:1.97.1.8] synonym: "tetrachloroethene reductase activity" EXACT [EC:1.97.1.8] xref: EC:1.97.1.8 xref: GO:0050629 xref: MetaCyc:1.97.1.8-RXN is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0007965 name: corydaline synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + palmatine + 2 NADPH + H+ = S-adenosyl-L-homocysteine + corydaline + 2 NADP+." [EC:2.1.1.147, MetaCyc:2.1.1.147-RXN] synonym: "S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity" EXACT [EC:2.1.1.147] xref: EC:2.1.1.147 xref: GO:0050631 xref: MetaCyc:2.1.1.147-RXN is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0007966 name: propionyl-CoA C2-trimethyltridecanoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA." [EC:2.3.1.154, MetaCyc:2.3.1.154-RXN] synonym: "3-oxopristanoyl-CoA hydrolase activity" EXACT [EC:2.3.1.154] synonym: "3-oxopristanoyl-CoA thiolase activity" EXACT [EC:2.3.1.154] synonym: "4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity" EXACT [EC:2.3.1.154] synonym: "4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity" EXACT [EC:2.3.1.154] synonym: "oxopristanoyl-CoA thiolase activity" EXACT [EC:2.3.1.154] synonym: "peroxisomal 3-oxoacyl coenzyme A thiolase" NARROW [EC:2.3.1.154] synonym: "peroxisome sterol carrier protein thiolase" NARROW [EC:2.3.1.154] synonym: "propionyl-CoA C(2)-trimethyltridecanoyltransferase activity" EXACT [] synonym: "SCPx" RELATED [EC:2.3.1.154] synonym: "sterol carrier protein" RELATED [EC:2.3.1.154] xref: EC:2.3.1.154 xref: GO:0050632 xref: MetaCyc:2.3.1.154-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007967 name: acetyl-CoA C-myristoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA." [EC:2.3.1.155, MetaCyc:2.3.1.155-RXN] synonym: "3-oxopalmitoyl-CoA hydrolase activity" EXACT [EC:2.3.1.155] synonym: "3-oxopalmitoyl-CoA-CoA acetyltransferase activity" EXACT [EC:2.3.1.155] synonym: "myristoyl-CoA C-acetyltransferase activity" EXACT [EC:2.3.1.155] synonym: "myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity" EXACT [EC:2.3.1.155] xref: EC:2.3.1.155 xref: GO:0050633 xref: MetaCyc:2.3.1.155-RXN is_a: CCO:F0003131 ! C-acyltransferase activity is_a: CCO:F0004053 ! myristoyltransferase activity [Term] id: CCO:F0007968 name: phloroisovalerophenone synthase activity namespace: molecular_function def: "Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one." [EC:2.3.1.156, MetaCyc:2.3.1.156-RXN] synonym: "3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity" EXACT [EC:2.3.1.156] synonym: "isovaleryl-CoA:malonyl-CoA acyltransferase activity" EXACT [EC:2.3.1.156] synonym: "valerophenone synthase activity" EXACT [EC:2.3.1.156] xref: EC:2.3.1.156 xref: GO:0050634 xref: MetaCyc:2.3.1.156-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007969 name: acridone synthase activity namespace: molecular_function def: "Catalysis of the reaction: 3 malonyl-CoA + N-methylanthraniloyl-CoA = 4 CoA + 1,3-dihydroxy-N-methylacridone + 3 CO2." [EC:2.3.1.159, MetaCyc:2.3.1.159-RXN] synonym: "malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing)" EXACT [EC:2.3.1.159] xref: EC:2.3.1.159 xref: GO:0050635 xref: MetaCyc:2.3.1.159-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007970 name: vinorine synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + 16-epivellosimine = CoA + vinorine." [EC:2.3.1.160, MetaCyc:2.3.1.160-RXN] synonym: "acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing)" EXACT [EC:2.3.1.160] xref: EC:2.3.1.160 xref: GO:0050636 xref: MetaCyc:2.3.1.160-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007971 name: lovastatin nonaketide synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + 8 malonyl-CoA + 11 NADPH + 11 H+ + S-adenosyl-L-methionine = dihydromonacolin L + 9 CoA + 8 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2O." [EC:2.3.1.161, MetaCyc:2.3.1.161-RXN] synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)" EXACT [EC:2.3.1.161] xref: EC:2.3.1.161 xref: GO:0050637 xref: MetaCyc:2.3.1.161-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007972 name: taxadien-5-alpha-ol O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5-alpha-ol = CoA + taxa-4(20),11-dien-5-alpha-yl acetate." [EC:2.3.1.162, MetaCyc:2.3.1.162-RXN] synonym: "acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity" EXACT [EC:2.3.1.162] synonym: "acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity" EXACT [EC:2.3.1.162] synonym: "acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity" EXACT [EC:2.3.1.162] synonym: "taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity" EXACT [EC:2.3.1.162] synonym: "taxadien-5a-ol O-acetyltransferase activity" EXACT [] synonym: "taxadien-5alpha-ol O-acetyltransferase activity" EXACT [EC:2.3.1.162] synonym: "taxadienol acetyltransferase activity" EXACT [EC:2.3.1.162] xref: EC:2.3.1.162 xref: GO:0050638 xref: MetaCyc:2.3.1.162-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0007973 name: 10-hydroxytaxane O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + 10-desacetyltaxuyunnanin C = CoA + taxuyunnanin C." [EC:2.3.1.163, MetaCyc:2.3.1.163-RXN] synonym: "acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity" EXACT [EC:2.3.1.163] synonym: "acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity" EXACT [EC:2.3.1.163] synonym: "acetyl-CoA:taxan-10beta-ol O-acetyltransferase" BROAD [EC:2.3.1.163] xref: EC:2.3.1.163 xref: GO:0050639 xref: MetaCyc:2.3.1.163-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0007974 name: isopenicillin-N N-acyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: phenylacetyl-CoA + isopenicillin-N + H2O = CoA + penicillin-G + L-2-aminohexanedioate." [EC:2.3.1.164, MetaCyc:2.3.1.164-RXN] synonym: "acyl-CoA:isopenicillin N N-acyltransferase activity" EXACT [EC:2.3.1.164] synonym: "acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity" EXACT [EC:2.3.1.164] synonym: "acyl-coenzyme A:isopenicillin N acyltransferase activity" EXACT [EC:2.3.1.164] synonym: "isopenicillin N:acyl-CoA acyltransferase activity" EXACT [EC:2.3.1.164] synonym: "isopenicillin-N acyltransferase activity" EXACT [] xref: EC:2.3.1.164 xref: GO:0042319 xref: GO:0045440 xref: GO:0050640 xref: MetaCyc:2.3.1.164-RXN is_a: CCO:F0003133 ! N-acyltransferase activity [Term] id: CCO:F0007975 name: 6-methylsalicylic acid synthase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + 3 malonyl-CoA + NADPH + H+ = 6-methylsalicylate + 4 CoA + 3 CO2 + NADP+." [EC:2.3.1.165, MetaCyc:2.3.1.165-RXN] synonym: "6-MSAS activity" EXACT [EC:2.3.1.165] synonym: "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)" EXACT [EC:2.3.1.165] synonym: "MSAS activity" EXACT [EC:2.3.1.165] xref: EC:2.3.1.165 xref: GO:0050641 xref: MetaCyc:2.3.1.165-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007976 name: 2-alpha-hydroxytaxane 2-O-benzoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: benzoyl-CoA + 10-deacetyl-2-debenzoylbaccatin III = CoA + 10-deacetylbaccatin III." [EC:2.3.1.166, MetaCyc:2.3.1.166-RXN] synonym: "2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity" EXACT [EC:2.3.1.166] synonym: "2a-hydroxytaxane 2-O-benzoyltransferase activity" EXACT [] synonym: "2alpha-hydroxytaxane 2-O-benzoyltransferase activity" EXACT [EC:2.3.1.166] synonym: "benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity" EXACT [EC:2.3.1.166] synonym: "benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity" EXACT [EC:2.3.1.166] synonym: "benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity" EXACT [EC:2.3.1.166] xref: EC:2.3.1.166 xref: GO:0050642 xref: MetaCyc:2.3.1.166-RXN is_a: CCO:F0003322 ! transferase activity, transferring groups other than amino-acyl groups [Term] id: CCO:F0007977 name: 10-deacetylbaccatin III 10-O-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III." [EC:2.3.1.167, MetaCyc:2.3.1.167-RXN] synonym: "acetyl-CoA:taxan-10beta-ol O-acetyltransferase" BROAD [EC:2.3.1.167] xref: EC:2.3.1.167 xref: GO:0050643 xref: MetaCyc:2.3.1.167-RXN is_a: CCO:F0003136 ! O-acetyltransferase activity [Term] id: CCO:F0007978 name: cis-p-coumarate glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: cis-p-coumarate + UDP-D-glucose = UDP + 4'-O-beta-D-glucosyl-cis-p-coumarate." [EC:2.4.1.209, MetaCyc:2.4.1.209-RXN] synonym: "UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity" EXACT [EC:2.4.1.209] xref: EC:2.4.1.209 xref: GO:0050644 xref: MetaCyc:2.4.1.209-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007979 name: limonoid glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP." [EC:2.4.1.210] synonym: "LGTase activity" EXACT [EC:2.4.1.210] synonym: "limonoid UDP-glucosyltransferase activity" EXACT [EC:2.4.1.210] synonym: "uridine diphosphoglucose-limonoid glucosyltransferase activity" EXACT [EC:2.4.1.210] xref: EC:2.4.1.210 xref: GO:0050645 xref: MetaCyc:2.4.1.210-RXN is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0007980 name: 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding namespace: molecular_function def: "Interacting selectively with 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds." [GOC:ai] synonym: "5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding" EXACT [] xref: GO:0050646 is_a: CCO:F0007877 ! icosatetraenoic acid binding [Term] id: CCO:F0007981 name: 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding namespace: molecular_function def: "Interacting selectively with 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds." [GOC:ai] synonym: "5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding" EXACT [] xref: GO:0050647 is_a: CCO:F0007877 ! icosatetraenoic acid binding [Term] id: CCO:F0007982 name: 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding namespace: molecular_function def: "Interacting selectively with 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds." [GOC:ai] synonym: "5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding" EXACT [] xref: GO:0050648 is_a: CCO:F0007877 ! icosatetraenoic acid binding [Term] id: CCO:F0007983 name: testosterone 6-beta-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O." [GOC:ai, PMID:11726664] synonym: "testosterone 6b-hydroxylase activity" EXACT [] xref: GO:0050649 is_a: CCO:F0001866 ! steroid hydroxylase activity [Term] id: CCO:F0007984 name: 3'-phosphoadenosine 5'-phosphosulfate binding namespace: molecular_function def: "Interacting selectively with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems." [GOC:ai] synonym: "3'-phosphoadenosine 5'-phosphosulphate binding" EXACT [] synonym: "3'-phosphoadenylyl-sulfate binding" EXACT [] synonym: "adenosine 3'-phosphate 5'-phosphosulfate binding" EXACT [] synonym: "PAPS binding" EXACT [] synonym: "phosphoadenosine phosphosulfate binding" EXACT [] xref: GO:0050656 is_a: CCO:F0004466 ! adenyl nucleotide binding [Term] id: CCO:F0007985 name: N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate." [EC:2.8.2.33] synonym: "3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity" EXACT [EC:2.8.2.33] synonym: "GalNAc4S-6ST" RELATED [EC:2.8.2.33] synonym: "N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity" EXACT [EC:2.8.2.33] xref: EC:2.8.2.33 xref: GO:0050659 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007986 name: FAD binding namespace: molecular_function def: "Interacting selectively with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes." [GOC:ai, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok synonym: "flavin adenine dinucleotide binding" EXACT [] synonym: "flavine-adenine dinucleotide binding" EXACT [] xref: GO:0050660 is_a: CCO:F0004466 ! adenyl nucleotide binding is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0007987 name: NADP binding namespace: molecular_function def: "Interacting selectively with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP, or the reduced form, NADPH." [GOC:ai] synonym: "NADP (oxidized) binding" EXACT [] synonym: "NADP (reduced) binding" EXACT [] synonym: "NADPH binding" EXACT [] synonym: "nicotinamide adenine dinucleotide phosphate binding" EXACT [] synonym: "oxidized NADP binding" EXACT [] synonym: "oxidized nicotinamide adenine dinucleotide phosphate binding" EXACT [] synonym: "reduced NADP binding" EXACT [] synonym: "reduced nicotinamide adenine dinucleotide phosphate binding" EXACT [] xref: GO:0050661 is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0007988 name: coenzyme binding namespace: molecular_function def: "Interacting selectively with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0050662 is_a: CCO:F0007309 ! cofactor binding [Term] id: CCO:F0007989 name: oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor namespace: molecular_function def: "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule." [EC:1.6.3.-] xref: EC:1.6.3 xref: GO:0050664 is_a: CCO:F0003249 ! oxidoreductase activity, acting on NADH or NADPH [Term] id: CCO:F0007990 name: androgen receptor binding namespace: molecular_function def: "Interacting selectively with an androgen receptor." [GOC:ai] synonym: "AR binding" EXACT [] xref: GO:0050681 is_a: CCO:F0005586 ! steroid hormone receptor binding [Term] id: CCO:F0007991 name: AF-2 domain binding namespace: molecular_function def: "Interacting selectively with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation." [PMID:9682036] xref: GO:0050682 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0007992 name: AF-1 domain binding namespace: molecular_function def: "Interacting selectively with the AF-1 domain of a protein, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor." [PMID:9682036] xref: GO:0050683 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0007993 name: DBD domain binding namespace: molecular_function def: "Interacting selectively with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors." [PMID:9682036] synonym: "DNA binding domain binding" EXACT [] xref: GO:0050692 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0007994 name: LBD domain binding namespace: molecular_function def: "Interacting selectively with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket." [PMID:9682036] synonym: "ligand binding domain binding" EXACT [] xref: GO:0050693 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0007995 name: galactose 3-O-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc." [GOC:ai, PMID:11323440, PMID:11356829] synonym: "Gal-3-O-sulfotransferase activity" EXACT [] synonym: "galactose 3-O-sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0050694 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007996 name: benzoylformate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: benzoylformate = benzaldehyde + CO2." [EC:4.1.1.7, MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN] subset: gosubset_prok synonym: "benzoylformate carboxy-lyase (benzaldehyde-forming)" EXACT [EC:4.1.1.7] synonym: "benzoylformate carboxy-lyase activity" EXACT [EC:4.1.1.7] synonym: "phenylglyoxylate decarboxylase activity" EXACT [] xref: EC:4.1.1.7 xref: GO:0050695 xref: MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN xref: UM-BBD_enzymeID:e0652 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0007997 name: 1,1,2-trichloroethene reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene." [MetaCyc:TCEREDCHLOR-RXN, UM-BBD_enzymeID:e0271] synonym: "1,1,2-trichloroethylene reductive dehalogenase activity" EXACT [] synonym: "TCE-reductive dehalogenase activity" EXACT [] xref: GO:0050697 xref: MetaCyc:TCEREDCHLOR-RXN xref: UM-BBD_enzymeID:e0271 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0007998 name: proteoglycan sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans." [EC:2.8.2.-, GOC:ai] synonym: "proteoglycan sulfate transfer" RELATED [] synonym: "proteoglycan sulphotransferase activity" EXACT [] xref: EC:2.8.2.- xref: GO:0050698 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0007999 name: WW domain binding namespace: molecular_function def: "Interacting selectively with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions." [PMID:14531730] xref: GO:0050699 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0008000 name: CARD domain binding namespace: molecular_function def: "Interacting selectively with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family." [PMID:12054670] xref: GO:0050700 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0008001 name: RS domain binding namespace: molecular_function def: "Interacting selectively with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing." [PMID:11684676, PMID:12215544] xref: GO:0050733 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0008002 name: hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule." [GOC:ai] xref: GO:0050734 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0008003 name: N-malonyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an malonyl group to a nitrogen atom on the acceptor molecule." [GOC:ai] xref: GO:0050735 is_a: CCO:F0003133 ! N-acyltransferase activity is_a: CCO:F0003143 ! malonyltransferase activity [Term] id: CCO:F0008004 name: O-malonyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an malonyl group to an oxygen atom on the acceptor molecule." [GOC:ai] xref: GO:0050736 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0003143 ! malonyltransferase activity [Term] id: CCO:F0008005 name: O-hydroxycinnamoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule." [GOC:ai] xref: GO:0050737 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0008002 ! hydroxycinnamoyltransferase activity [Term] id: CCO:F0008006 name: fructosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid." [GOC:ai] xref: GO:0050738 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0008007 name: apolipoprotein E receptor binding namespace: molecular_function def: "Interacting selectively with an apolipoprotein E receptor." [GOC:ai] xref: GO:0050749 is_a: CCO:F0005528 ! apolipoprotein receptor binding is_a: CCO:F0008008 ! low-density lipoprotein receptor binding [Term] id: CCO:F0008008 name: low-density lipoprotein receptor binding namespace: molecular_function def: "Interacting selectively with a low density lipoprotein receptor." [GOC:ai] synonym: "LDL receptor binding" EXACT [] xref: GO:0050750 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0008009 name: dopamine receptor binding namespace: molecular_function def: "Interacting selectively with a dopamine receptor." [GOC:ai] xref: GO:0050780 is_a: CCO:F0000196 ! G-protein-coupled receptor binding [Term] id: CCO:F0008010 name: ortho-trichlorophenol reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4,6-trichlorophenol +2 H+ + 2 e- = 2,4-dichlorophenol + HCl." [GOC:ai, PMID:12697029] subset: gosubset_prok synonym: "2,4,6-TCP reductive dehalogenase activity" EXACT [] synonym: "2,4,6-trichlorophenol reductive dehalogenase activity" EXACT [] xref: GO:0050781 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008011 name: galactose uniporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in)." [GOC:ai, TC:2.A.1.1.6] synonym: "galactose, glucose uniporter activity" BROAD [] xref: GO:0050782 is_a: CCO:F0001580 ! galactose transmembrane transporter activity is_a: CCO:F0001969 ! hexose uniporter activity [Term] id: CCO:F0008012 name: advanced glycation end-product receptor activity namespace: molecular_function def: "Combining with advanced glycation end-products to initiate a change in cell activity." [PMID:12453678, PMID:12707408, PMID:7592757, PMID:9224812] synonym: "RAGE receptor activity" EXACT [] xref: GO:0050785 is_a: CCO:F0001226 ! receptor activity [Term] id: CCO:F0008013 name: RAGE receptor binding namespace: molecular_function def: "Interacting selectively with the RAGE receptor, the receptor for advanced glycation end-products." [GOC:ai] synonym: "advanced glycation end-product receptor binding" EXACT [] xref: GO:0050786 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0008014 name: thymidylate synthase (FAD) activity namespace: molecular_function def: "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + FADH2 = dTMP + tetrahydrofolate + FAD." [EC:2.1.1.148] subset: gosubset_prok synonym: "5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity" EXACT [EC:2.1.1.148] synonym: "FDTS activity" EXACT [EC:2.1.1.148] synonym: "flavin dependent thymidylate synthase activity" EXACT [EC:2.1.1.148] synonym: "Thy1 activity" EXACT [] synonym: "ThyX activity" EXACT [] xref: EC:2.1.1.148 xref: GO:0050797 is_a: CCO:F0005619 ! 5,10-methylenetetrahydrofolate-dependent methyltransferase activity [Term] id: CCO:F0008015 name: diazepam binding namespace: molecular_function def: "Interacting selectively with diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "diazepam binding inhibitor activity" RELATED [] synonym: "Valium binding" EXACT [] xref: GO:0050809 is_a: CCO:F0001746 ! drug binding [Term] id: CCO:F0008016 name: GABA receptor binding namespace: molecular_function def: "Interacting selectively with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor." [GOC:ai] synonym: "4-aminobutanoate receptor binding" EXACT [] synonym: "4-aminobutyrate receptor binding" EXACT [] synonym: "diazepam binding inhibitor activity" RELATED [] synonym: "gamma-aminobutyric acid receptor binding" EXACT [] xref: GO:0050811 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0008017 name: phosphoserine binding namespace: molecular_function def: "Interacting selectively with a phosphorylated serine residue within a protein." [GOC:ai] synonym: "phosphoserine/phosphothreonine binding" BROAD [] xref: GO:0050815 is_a: CCO:F0006109 ! protein phosphorylated amino acid binding [Term] id: CCO:F0008018 name: phosphothreonine binding namespace: molecular_function def: "Interacting selectively with a phosphorylated threonine residue within a protein." [GOC:ai] synonym: "phosphoserine/phosphothreonine binding" BROAD [] xref: GO:0050816 is_a: CCO:F0006109 ! protein phosphorylated amino acid binding [Term] id: CCO:F0008019 name: water binding namespace: molecular_function def: "Interacting selectively with water (H2O)." [GOC:ai] subset: goslim_pir subset: gosubset_prok xref: GO:0050824 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008020 name: ice binding namespace: molecular_function def: "Interacting selectively with ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal." [http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "antifreeze activity" RELATED [] synonym: "ice crystal binding" EXACT [] synonym: "ice nucleation activity" RELATED [] synonym: "ice nucleation inhibitor activity" RELATED [] xref: GO:0050825 is_a: CCO:F0008019 ! water binding [Term] id: CCO:F0008021 name: toxin receptor binding namespace: molecular_function def: "Interacting selectively with a toxin receptor, a receptor for substances that cause injury to living organisms." [GOC:ai] synonym: "channel-forming toxin activity" RELATED [] synonym: "cytotoxin activity" RELATED [] synonym: "endotoxin activity" RELATED [] synonym: "enterotoxin activity" RELATED [] synonym: "exotoxin activity" RELATED [] synonym: "lipoprotein toxin" RELATED [] synonym: "neurotoxin activity" RELATED [] synonym: "pore-forming toxin activity" RELATED [] synonym: "toxin activity" RELATED [] xref: GO:0050827 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0008022 name: pyruvate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of pyruvate, 2-oxopropanoate, from one side of the membrane to the other." [GOC:ai] synonym: "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity" NARROW [] xref: GO:0050833 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0008023 name: cell adhesion molecule binding namespace: molecular_function def: "Interacting selectively with a cell adhesion molecule." [GOC:ai] synonym: "adhesive extracellular matrix constituent" RELATED [] synonym: "CAM binding" EXACT [] synonym: "cell adhesion molecule activity" RELATED [] synonym: "cell adhesion receptor activity" RELATED [] xref: GO:0050839 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0008024 name: extracellular matrix binding namespace: molecular_function def: "Interacting selectively with a component of the extracellular matrix." [GOC:ai] subset: goslim_pir subset: gosubset_prok synonym: "adhesive extracellular matrix constituent" RELATED [] synonym: "extracellular matrix constituent binding" EXACT [] xref: GO:0050840 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008025 name: cobalt ion binding namespace: molecular_function def: "Interacting selectively with a cobalt (Co) ion." [GOC:ai] subset: gosubset_prok synonym: "cobalt binding" EXACT [] xref: GO:0050897 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0008026 name: quaternary ammonium group binding namespace: molecular_function def: "Interacting selectively with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups." [GOC:ai] subset: gosubset_prok synonym: "quaternary amine binding" EXACT [] xref: GO:0050997 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008027 name: nitric-oxide synthase binding namespace: molecular_function def: "Interacting selectively with the enzyme nitric-oxide synthase." [GOC:ai] synonym: "NOS binding" EXACT [] xref: GO:0050998 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0008028 name: ligase activity, forming nitrogen-metal bonds namespace: molecular_function def: "Catalysis of the ligation of two substances via a nitrogen-metal bond." [EC:6.6.-.-] subset: gosubset_prok xref: EC:6.6 xref: GO:0051002 is_a: CCO:F0003433 ! ligase activity [Term] id: CCO:F0008029 name: ligase activity, forming nitrogen-metal bonds, forming coordination complexes namespace: molecular_function def: "Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex." [EC:6.6.1.-] subset: gosubset_prok xref: EC:6.6.1 xref: GO:0051003 is_a: CCO:F0008028 ! ligase activity, forming nitrogen-metal bonds [Term] id: CCO:F0008030 name: squalene-hopene cyclase activity namespace: molecular_function def: "Catalysis of the reaction: squalene = hop-22(29)-ene." [EC:5.4.99.17] subset: gosubset_prok synonym: "squalene mutase (cyclizing)" EXACT [EC:5.4.99.17] synonym: "squalene:hopene cyclase activity" EXACT [PMID:18033581] xref: EC:5.4.99.17 xref: GO:0051007 is_a: CCO:F0003427 ! intramolecular transferase activity is_a: CCO:F0005516 ! squalene cyclase activity [Term] id: CCO:F0008031 name: Hsp27 protein binding namespace: molecular_function def: "Interacting selectively with Hsp27 proteins, a lightweight heat shock protein." [GOC:ai] xref: GO:0051008 is_a: CCO:F0004628 ! heat shock protein binding [Term] id: CCO:F0008032 name: O-acetylhomoserine sulfhydrylase activity namespace: molecular_function def: "Catalysis of the reaction: O-acetyl-L-homoserine + H2S = homocysteine + acetate." [MetaCyc:ACETYLHOMOSER-CYS-RXN] xref: GO:0051009 xref: MetaCyc:ACETYLHOMOSER-CYS-RXN is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0008033 name: microtubule plus-end binding namespace: molecular_function def: "Interacting selectively with the plus end of a microtubule." [GOC:ai, PMID:14557818, PMID:14614826] xref: GO:0051010 is_a: CCO:F0001679 ! microtubule binding [Term] id: CCO:F0008034 name: microtubule minus-end binding namespace: molecular_function def: "Interacting selectively with the minus end of a microtubule." [GOC:ai, PMID:14557818, PMID:14614826] xref: GO:0051011 is_a: CCO:F0001679 ! microtubule binding [Term] id: CCO:F0008035 name: actin filament binding namespace: molecular_function def: "Interacting selectively with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "actin cross-linking activity" RELATED [] synonym: "F-actin binding" EXACT [] xref: GO:0051015 is_a: CCO:F0000323 ! actin binding [Term] id: CCO:F0008036 name: protein kinase A binding namespace: molecular_function def: "Interacting selectively with any subunit of protein kinase A." [GOC:ai] comment: Note that this term is a direct child of 'protein binding ; GO:0005515' because it encompasses binding to either the catalytic or regulatory subunit of protein kinase A, and the latter does not have kinase activity. synonym: "PKA binding" EXACT [] synonym: "protein kinase A anchoring activity" RELATED [] xref: GO:0051018 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0008037 name: mitogen-activated protein kinase binding namespace: molecular_function def: "Interacting selectively with a mitogen-activated protein kinase." [GOC:ai] synonym: "MAP kinase binding" EXACT [] synonym: "MAP-kinase anchoring activity" RELATED [] synonym: "MAPK binding" EXACT [] xref: GO:0051019 is_a: CCO:F0004210 ! protein kinase binding [Term] id: CCO:F0008038 name: GTPase binding namespace: molecular_function def: "Interacting selectively with a GTPase, any enzyme that catalyzes the hydrolysis of GTP." [GOC:ai] xref: GO:0051020 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0008039 name: GDP-dissociation inhibitor binding namespace: molecular_function def: "Interacting selectively with a GDP-dissociation inhibitor protein." [GOC:ai] synonym: "GDI binding" EXACT [] xref: GO:0051021 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0008040 name: Rho GDP-dissociation inhibitor binding namespace: molecular_function def: "Interacting selectively with a Rho GDP-dissociation inhibitor protein." [GOC:ai] synonym: "Rho GDI binding" EXACT [] xref: GO:0051022 is_a: CCO:F0008039 ! GDP-dissociation inhibitor binding [Term] id: CCO:F0008041 name: nucleic acid transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai] xref: GO:0051032 is_a: CCO:F0003026 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity [Term] id: CCO:F0008042 name: RNA transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: GO:0051033 is_a: CCO:F0008041 ! nucleic acid transmembrane transporter activity [Term] id: CCO:F0008043 name: tRNA transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: GO:0051034 is_a: CCO:F0008042 ! RNA transmembrane transporter activity [Term] id: CCO:F0008044 name: DNA transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: GO:0051035 is_a: CCO:F0008041 ! nucleic acid transmembrane transporter activity [Term] id: CCO:F0008045 name: NF-kappaB binding namespace: molecular_function def: "Interacting selectively with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters." [GOC:ai] xref: GO:0051059 is_a: CCO:F0001738 ! transcription factor binding [Term] id: CCO:F0008046 name: pullulanase activity namespace: molecular_function def: "Catalysis of the hydrolysis of (1,6)-a-D-glucosidic linkages in pullulan [a linear polymer of a-(1,6)-linked maltotriose units] and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen." [EC:3.2.1.41] subset: gosubset_prok synonym: "alpha-dextrin endo-1,6-alpha-glucosidase activity" EXACT [] synonym: "amylopectin 6-glucanohydrolase activity" EXACT [] synonym: "bacterial debranching enzyme" RELATED [EC:3.2.1.41] synonym: "debranching enzyme activity" BROAD [EC:3.2.1.41] synonym: "limit dextrinase (erroneous)" BROAD [EC:3.2.1.41] synonym: "pullulan 6-glucanohydrolase activity" EXACT [] synonym: "pullulan alpha-1,6-glucanohydrolase activity" EXACT [EC:3.2.1.41] synonym: "R-enzyme" RELATED [EC:3.2.1.41] xref: EC:3.2.1.41 xref: GO:0051060 is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0008047 name: ADP reductase activity namespace: molecular_function def: "Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin." [MetaCyc:ADPREDUCT-RXN] synonym: "ADP reduction" RELATED [] xref: GO:0051061 xref: MetaCyc:ADPREDUCT-RXN is_a: CCO:F0001113 ! ribonucleoside-diphosphate reductase activity [Term] id: CCO:F0008048 name: UDP reductase activity namespace: molecular_function def: "Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin." [MetaCyc:UDPREDUCT-RXN] synonym: "UDP reduction" RELATED [] xref: GO:0051062 xref: MetaCyc:UDPREDUCT-RXN is_a: CCO:F0001113 ! ribonucleoside-diphosphate reductase activity [Term] id: CCO:F0008049 name: CDP reductase activity namespace: molecular_function def: "Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin." [MetaCyc:CDPREDUCT-RXN] synonym: "CDP reduction" RELATED [] xref: GO:0051063 xref: MetaCyc:CDPREDUCT-RXN is_a: CCO:F0001113 ! ribonucleoside-diphosphate reductase activity [Term] id: CCO:F0008050 name: TTP reductase activity namespace: molecular_function def: "Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin." [MetaCyc:1.17.4.2-RXN] synonym: "TTP reduction" RELATED [] xref: EC:1.17.4.- xref: GO:0051064 is_a: CCO:F0002330 ! ribonucleoside-triphosphate reductase activity [Term] id: CCO:F0008051 name: CTP reductase activity namespace: molecular_function def: "Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin." [MetaCyc:1.17.4.2-RXN] synonym: "CTP reduction" RELATED [] xref: EC:1.17.4.- xref: GO:0051065 is_a: CCO:F0002330 ! ribonucleoside-triphosphate reductase activity [Term] id: CCO:F0008052 name: adenosylcobinamide-GDP ribazoletransferase activity namespace: molecular_function def: "Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin." [EC:2.7.8.26, MetaCyc:COBALAMINSYN-RXN] synonym: "adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase activity" EXACT [EC:2.7.8.26] synonym: "cobalamin (5'-phosphate) synthase activity" EXACT [EC:2.7.8.26] synonym: "cobalamin synthase activity" EXACT [] synonym: "cobalamin-5'-phosphate synthase activity" EXACT [EC:2.7.8.26] synonym: "CobS" RELATED [EC:2.7.8.26] xref: EC:2.7.8.26 xref: GO:0051073 xref: MetaCyc:COBALAMINSYN-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0008053 name: S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA [preQ1-tRNA] = adenine + methionine + epoxyqueuosine-tRNA [oQ-tRNA]." [PMID:12731872] subset: gosubset_prok synonym: "S-adenosyl methionine:tRNA ribosyltransferase-isomerase activity" EXACT [] xref: GO:0051075 is_a: CCO:F0003316 ! transferase activity is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0008054 name: Gram-positive bacterial binding namespace: molecular_function def: "Interacting selectively with any part of a Gram-positive bacterial cell." [GOC:ai] subset: gosubset_prok synonym: "binding to Gram-positive bacterium" EXACT [] synonym: "Gram-positive bacterium binding" EXACT [] xref: GO:0051076 is_a: CCO:F0001847 ! bacterial binding [Term] id: CCO:F0008055 name: unfolded protein binding namespace: molecular_function def: "Interacting selectively with an unfolded protein." [GOC:ai] subset: gosubset_prok synonym: "binding unfolded ER proteins" NARROW [] synonym: "chaperone activity" RELATED [] synonym: "fimbrium-specific chaperone activity" RELATED [] synonym: "glycoprotein-specific chaperone activity" RELATED [] synonym: "histone-specific chaperone activity" RELATED [] synonym: "ribosomal chaperone activity" RELATED [] synonym: "tubulin-specific chaperone activity" RELATED [] xref: GO:0051082 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0008056 name: chaperone binding namespace: molecular_function def: "Interacting selectively with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport." [http://www.onelook.com] subset: gosubset_prok synonym: "chaperone protein binding" EXACT [] synonym: "co-chaperone activity" RELATED [] synonym: "co-chaperonin activity" RELATED [] xref: GO:0051087 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0008057 name: carnitine-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA." [MetaCyc:DCARNCOALIG-RXN] synonym: "carnitine synthetase activity" EXACT [] synonym: "crotonobetaine/carnitine-CoA ligase activity" BROAD [] xref: GO:0051108 xref: MetaCyc:DCARNCOALIG-RXN is_a: CCO:F0003128 ! CoA-ligase activity is_a: CCO:F0003440 ! acid-amino acid ligase activity [Term] id: CCO:F0008058 name: crotonobetaine-CoA ligase activity namespace: molecular_function def: "Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA." [MetaCyc:CROTCOALIG-RXN] synonym: "crotonobetaine-CoA synthase activity" EXACT [] synonym: "crotonobetaine/carnitine-CoA ligase activity" BROAD [] xref: GO:0051109 xref: MetaCyc:CROTCOALIG-RXN is_a: CCO:F0003128 ! CoA-ligase activity [Term] id: CCO:F0008059 name: cobaltochelatase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + hydrogenobyrinic acid a,c-diamide + Co2+ = ADP + phosphate + cob(II)yrinic acid a,c-diamide + H+." [EC:6.6.1.2] subset: gosubset_prok synonym: "CobN-CobST" RELATED [EC:6.6.1.2] synonym: "CobNST" NARROW [] synonym: "hydrogenobyrinic acid a,c-diamide cobaltochelatase activity" EXACT [] synonym: "hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)" EXACT [EC:6.6.1.2] xref: EC:6.6.1.2 xref: GO:0051116 xref: MetaCyc:R342-RXN is_a: CCO:F0008029 ! ligase activity, forming nitrogen-metal bonds, forming coordination complexes [Term] id: CCO:F0008060 name: ATPase binding namespace: molecular_function def: "Interacting selectively with an ATPase, any enzyme that catalyzes the hydrolysis of ATP." [GOC:ai] xref: GO:0051117 is_a: CCO:F0004208 ! enzyme binding [Term] id: CCO:F0008061 name: glucan endo-1,3-alpha-glucosidase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of 1,3-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran." [EC:3.2.1.59] synonym: "1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity" EXACT [EC:3.2.1.59] synonym: "cariogenanase activity" EXACT [EC:3.2.1.59] synonym: "cariogenase activity" EXACT [EC:3.2.1.59] synonym: "endo-(1->3)-alpha-glucanase activity" EXACT [EC:3.2.1.59] synonym: "endo-1,3-alpha-D-glucanase activity" EXACT [EC:3.2.1.59] synonym: "endo-1,3-alpha-glucanase activity" EXACT [EC:3.2.1.59] synonym: "mutanase activity" EXACT [EC:3.2.1.59] xref: EC:3.2.1.59 xref: GO:0051118 is_a: CCO:F0003021 ! glucosidase activity [Term] id: CCO:F0008062 name: sugar transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a sugar from one side of the membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] subset: gosubset_prok synonym: "sugar/polyol channel activity" NARROW [] xref: GO:0051119 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0008063 name: hepoxilin A3 synthase activity namespace: molecular_function def: "Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid [12S-HpETE] = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate [hepoxilin A3]." [PMID:15123652] xref: GO:0051120 is_a: CCO:F0003416 ! isomerase activity [Term] id: CCO:F0008064 name: metal ion:hydrogen antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in)." [GOC:mlg] subset: gosubset_prok synonym: "metal ion:proton antiporter activity" EXACT [] xref: GO:0051139 is_a: CCO:F0002748 ! solute:hydrogen antiporter activity [Term] id: CCO:F0008065 name: vitamin transporter activity namespace: molecular_function def: "Enables the directed movement of vitamins into, out of, within or between cells. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] subset: gosubset_prok synonym: "vitamin or cofactor transporter activity" BROAD [] xref: GO:0051183 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0008066 name: cofactor transporter activity namespace: molecular_function def: "Enables the directed movement of a cofactor into, out of, within or between cells. A cofactor is a substance that is required for the activity of an enzyme or other protein." [GOC:ai] subset: gosubset_prok synonym: "vitamin or cofactor transporter activity" BROAD [] xref: GO:0051184 is_a: CCO:F0001491 ! transporter activity [Term] id: CCO:F0008067 name: coenzyme transporter activity namespace: molecular_function def: "Enables the directed movement of a coenzyme into, out of, within or between cells. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed." [GOC:ai] xref: GO:0051185 is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0008068 name: prosthetic group binding namespace: molecular_function def: "The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules." [GOC:ai] subset: gosubset_prok xref: GO:0051192 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008069 name: vanadium ion binding namespace: molecular_function def: "Interacting selectively with vanadium (V) ions." [GOC:ai] subset: gosubset_prok xref: GO:0051212 is_a: CCO:F0006268 ! transition metal ion binding [Term] id: CCO:F0008070 name: dioxygenase activity namespace: molecular_function def: "Catalysis of the incorporation of both atoms of oxygen from one molecule of O2 into the (reduced) substrate." [http://www.onelook.com/] subset: goslim_pir subset: gosubset_prok xref: GO:0051213 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008071 name: phosphoprotein binding namespace: molecular_function def: "Interacting selectively with a phosphorylated protein." [GOC:ai] synonym: "phosphorylated protein binding" EXACT [] xref: GO:0051219 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0008072 name: mono-olein transacylation activity namespace: molecular_function def: "Catalysis of the reaction: mono-olein (mono-oleoylglycerol) + mono-olein = diolein (dioleoylglycerol) + glycerol. Mono-olein is the monoglyceride formed from oleic acid, 9-octodecenoic acid." [GOC:ai, PMID:15364929] synonym: "acyl-CoA-independent mono-olein transacylation" EXACT [] synonym: "MOG transacylation" EXACT [] synonym: "mono-oleoylglycerol O-acyltransferase activity" EXACT [] synonym: "mono-oleoylglycerol transacylase activity" EXACT [] synonym: "monoolein transacylation" EXACT [] synonym: "monooleoylglycerol O-acyltransferase activity" EXACT [] synonym: "monooleoylglycerol transacylase activity" EXACT [] xref: GO:0051264 is_a: CCO:F0003134 ! acylglycerol O-acyltransferase activity [Term] id: CCO:F0008073 name: diolein transacylation activity namespace: molecular_function def: "Catalysis of the reaction: diolein (dioleoylglycerol) + mono-olein (mono-oleoylglycerol) = triolein (trioleoylglycerol) + glycerol. Mono-olein is the monoglyceride formed from oleic acid, 9-octodecenoic acid; triolein or trioleoylglycerol is also known as olein." [GOC:ai, PMID:15364929] synonym: "acyl-CoA-independent diolein transacylation" EXACT [] synonym: "dioleoylglycerol O-acyltransferase activity" EXACT [] synonym: "dioleoylglycerol transacylase activity" EXACT [] synonym: "DOG transacylation" EXACT [] xref: GO:0051265 is_a: CCO:F0003134 ! acylglycerol O-acyltransferase activity [Term] id: CCO:F0008074 name: sirohydrochlorin ferrochelatase activity namespace: molecular_function def: "Catalysis of the reaction: sirohydrochlorin + Fe2+ = siroheme + 2 H+." [EC:4.99.1.4, MetaCyc:SIROHEME-FERROCHELAT-RXN] subset: gosubset_prok synonym: "CysG" RELATED [EC:4.99.1.4] synonym: "Met8P" RELATED [EC:4.99.1.4] synonym: "SirB" RELATED [EC:4.99.1.4] synonym: "siroheme ferro-lyase (sirohydrochlorin-forming)" EXACT [EC:4.99.1.4] synonym: "siroheme synthase activity" BROAD [] synonym: "sirohydrochlorin ferro-lyase activity" EXACT [] xref: EC:4.99.1.4 xref: GO:0051266 xref: MetaCyc:SIROHEME-FERROCHELAT-RXN is_a: CCO:F0000745 ! ferrochelatase activity [Term] id: CCO:F0008075 name: CP2 mannose-ethanolamine phosphotransferase activity namespace: molecular_function def: "Catalysis of the reaction: ethanolamine phosphate (EtN-P) + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2." [PMID:14985347, PMID:15452134] synonym: "addition of ethanolamine phosphate to mannose of GPI precursor CP2" EXACT [] synonym: "CP2 ethanolamine phosphate transferase activity" EXACT [] synonym: "CP2 EtN-P transferase activity" EXACT [] synonym: "CP2 phosphoethanolamine transferase activity" EXACT [] synonym: "gpi7 activity" RELATED [] xref: GO:0051267 is_a: CCO:F0008086 ! mannose-ethanolamine phosphotransferase activity [Term] id: CCO:F0008076 name: alpha-keto amide reductase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic." [GOC:ai, PMID:15564669] xref: EC:1.2.-.- xref: GO:0051268 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0008077 name: alpha-keto ester reductase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic." [GOC:ai, PMID:15564669] xref: EC:1.2.-.- xref: GO:0051269 is_a: CCO:F0003460 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors [Term] id: CCO:F0008078 name: NAD binding namespace: molecular_function def: "Interacting selectively with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD, or the reduced form, NADH." [GOC:ai] synonym: "NAD (oxidized) binding" EXACT [] synonym: "NAD (reduced) binding" EXACT [] synonym: "NADH binding" EXACT [] synonym: "nicotinamide adenine dinucleotide binding" EXACT [] synonym: "oxidized NAD binding" EXACT [] synonym: "oxidized nicotinamide adenine dinucleotide binding" EXACT [] synonym: "reduced NAD binding" EXACT [] synonym: "reduced nicotinamide adenine dinucleotide binding" EXACT [] xref: GO:0051287 xref: GO:0051288 is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0008079 name: ZASP binding namespace: molecular_function def: "Interacting selectively with Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain." [PMID:10427098, PMID:11699871] synonym: "Z-band alternatively spliced PDZ-motif protein binding" EXACT [] xref: GO:0051370 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0008080 name: muscle alpha-actinin binding namespace: molecular_function def: "Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc." [PMID:10984498, PMID:11699871, PMID:15014165] synonym: "alpha-actinin 2 binding" NARROW [] synonym: "alpha-actinin 3 binding" NARROW [] xref: GO:0051371 is_a: CCO:F0008092 ! alpha-actinin binding [Term] id: CCO:F0008081 name: nonmuscle alpha-actinin binding namespace: molecular_function def: "Interacting selectively with nonmuscle isoforms of actinin. Nonmuscle alpha-actinin is found at the leading edge of motile cells, cell adhesion sites, focal contacts and along actin stress fibers in migrating cells." [PMID:15014165] synonym: "alpha-actinin 1 binding" NARROW [] synonym: "alpha-actinin 4 binding" EXACT [] xref: GO:0051372 is_a: CCO:F0008092 ! alpha-actinin binding [Term] id: CCO:F0008082 name: FATZ binding namespace: molecular_function def: "Interacting selectively with a family of FATZ proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components." [PMID:10984498, PMID:11699871] synonym: "calsarcin binding" EXACT [] synonym: "filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle" EXACT [] xref: GO:0051373 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0008083 name: FATZ 1 binding namespace: molecular_function def: "Interacting selectively with FATZ 1, a protein of FATZ family that is highly expressed in skeletal muscle fast fiber." [PMID:10984498, PMID:11699871] synonym: "calsarcin 2 binding" EXACT [] xref: GO:0051374 is_a: CCO:F0008082 ! FATZ binding [Term] id: CCO:F0008084 name: FATZ 2 binding namespace: molecular_function def: "Interacting selectively with FATZ 2, a protein of the FATZ family that is highly expressed in skeletal muscle fiber fast IIa and slow I and in cardiac muscle." [PMID:10984498, PMID:11699871] synonym: "calsarcin 1 binding" EXACT [] xref: GO:0051375 is_a: CCO:F0008082 ! FATZ binding [Term] id: CCO:F0008085 name: FATZ 3 binding namespace: molecular_function def: "Interacting selectively with FATZ 3, a protein of the FATZ family that is highly expressed in skeletal muscle fast fiber." [PMID:10984498, PMID:11699871] synonym: "calsarcin 3 binding" EXACT [] xref: GO:0051376 is_a: CCO:F0008082 ! FATZ binding [Term] id: CCO:F0008086 name: mannose-ethanolamine phosphotransferase activity namespace: molecular_function def: "Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor." [PMID:15632136] synonym: "addition of ethanolamine phosphate to mannose of GPI precursor" EXACT [] synonym: "ethanolamine phosphate transferase activity" BROAD [] synonym: "EtN-P transferase activity" EXACT [] synonym: "phosphoethanolamine transferase activity" BROAD [] xref: GO:0051377 is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0008087 name: serotonin binding namespace: molecular_function def: "Interacting selectively with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:ai] synonym: "5-hydroxytryptamine binding" EXACT [] xref: GO:0051378 is_a: CCO:F0005633 ! neurotransmitter binding is_a: CCO:F0005682 ! hormone binding is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0008088 name: epinephrine binding namespace: molecular_function def: "Interacting selectively with epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine." [GOC:ai] synonym: "adrenaline binding" EXACT [] xref: GO:0051379 is_a: CCO:F0005633 ! neurotransmitter binding is_a: CCO:F0005682 ! hormone binding is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0008089 name: norepinephrine binding namespace: molecular_function def: "Interacting selectively with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] synonym: "noradrenaline binding" EXACT [] xref: GO:0051380 is_a: CCO:F0005633 ! neurotransmitter binding is_a: CCO:F0005682 ! hormone binding is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0008090 name: histamine binding namespace: molecular_function def: "Interacting selectively with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans." [GOC:ai] xref: GO:0051381 is_a: CCO:F0005633 ! neurotransmitter binding is_a: CCO:F0005810 ! amine binding [Term] id: CCO:F0008091 name: tRNA N-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA." [PMID:15037780] synonym: "tRNA cytidine N-acetyltransferase activity" EXACT [] xref: GO:0051392 is_a: CCO:F0001700 ! N-acetyltransferase activity [Term] id: CCO:F0008092 name: alpha-actinin binding namespace: molecular_function def: "Interacting selectively with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats." [PMID:10984498, PMID:11699871, PMID:15014165] xref: GO:0051393 is_a: CCO:F0005715 ! actinin binding [Term] id: CCO:F0008093 name: N-terminal basic amino acid aminopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of basic amino acid residues at the N-terminal of an oligopeptide or polypeptide chain." [GOC:ai] xref: GO:0051397 is_a: CCO:F0000646 ! aminopeptidase activity [Term] id: CCO:F0008094 name: N-terminal lysine aminopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of a lysine residue from the N-terminal of an oligopeptide or polypeptide chain." [GOC:ai, PMID:12799365] synonym: "lysine aminopeptidase activity" BROAD [] synonym: "lysyl aminopeptidase activity" BROAD [] xref: GO:0051398 is_a: CCO:F0008093 ! N-terminal basic amino acid aminopeptidase activity [Term] id: CCO:F0008095 name: N-terminal arginine aminopeptidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain." [GOC:ai, PMID:12799365] synonym: "arginine aminopeptidase activity" BROAD [] synonym: "argininyl aminopeptidase activity" BROAD [] xref: GO:0051399 is_a: CCO:F0008093 ! N-terminal basic amino acid aminopeptidase activity [Term] id: CCO:F0008096 name: BH domain binding namespace: molecular_function def: "Interacting selectively with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409] synonym: "Bcl-2 homology domain binding" EXACT [] xref: GO:0051400 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0008097 name: CH domain binding namespace: molecular_function def: "Interacting selectively with the calponin homology domain of a protein, a domain of 100 residues that occurs in signaling and cytoskeletal proteins." [PMID:11911887, Prosite:PDOC50021] synonym: "calponin homology domain binding" EXACT [] xref: GO:0051401 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0008098 name: clostripain activity namespace: molecular_function def: "Catalysis of the cleavage of Arg-Xaa bonds." [EC:3.4.22.8] synonym: "alpha-clostridipain" RELATED [EC:3.4.22.8] synonym: "clostridiopeptidase B activity" EXACT [] synonym: "Clostridium histolyticum proteinase B" RELATED [EC:3.4.22.8] xref: EC:3.4.22.8 xref: GO:0051404 is_a: CCO:F0000666 ! cysteine-type endopeptidase activity [Term] id: CCO:F0008099 name: microbial collagenase activity namespace: molecular_function def: "Catalysis of the digestion of native collagen in the triple helical region at Xaa-Gly bonds." [EC:3.4.24.3] synonym: "Achromobacter iophagus collagenase" RELATED [EC:3.4.24.3] synonym: "aspergillopeptidase C" RELATED [EC:3.4.24.3] synonym: "azocollase activity" EXACT [EC:3.4.24.3] synonym: "clostridiopeptidase A activity" EXACT [] synonym: "clostridiopeptidase I" RELATED [EC:3.4.24.3] synonym: "clostridiopeptidase II" RELATED [EC:3.4.24.3] synonym: "Clostridium histolyticum collagenase activity" NARROW [EC:3.4.24.3] synonym: "Clostridium histolyticum proteinase A" RELATED [EC:3.4.24.3] synonym: "collagen peptidase activity" EXACT [EC:3.4.24.3] synonym: "collagen protease activity" EXACT [EC:3.4.24.3] synonym: "collagenase 1 activity" EXACT [] synonym: "collagenase A activity" EXACT [] synonym: "collagenase I activity" EXACT [EC:3.4.24.3] synonym: "collagenase MMP-1" RELATED [EC:3.4.24.3] synonym: "kollaza" RELATED [EC:3.4.24.3] synonym: "matirx metalloproteinase-18" RELATED [EC:3.4.24.3] synonym: "matrix metalloproteinase-1" RELATED [EC:3.4.24.3] synonym: "matrix metalloproteinase-8" RELATED [EC:3.4.24.3] synonym: "metallocollagenase activity" EXACT [EC:3.4.24.3] synonym: "metalloproteinase-1" RELATED [EC:3.4.24.3] synonym: "nucleolysin" RELATED [EC:3.4.24.3] synonym: "soycollagestin" RELATED [EC:3.4.24.3] xref: EC:3.4.24.3 xref: GO:0051405 is_a: CCO:F0001737 ! collagenase activity [Term] id: CCO:F0008100 name: beta-actinin binding namespace: molecular_function def: "Interacting selectively with beta-actinin, a heterodimeric actin-binding protein which caps the barbed end of actin filaments and nucleates actin polymerization in a calcium-independent manner. In myofibrils it is localized in the Z-lines." [PMID:11699871, PMID:2341404, PMID:9742448] synonym: "capZ binding" EXACT [] xref: GO:0051406 is_a: CCO:F0005715 ! actinin binding [Term] id: CCO:F0008101 name: glycerone phosphate:inorganic phosphate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out)." [GOC:ai] synonym: "dihydroxyacetone-phosphate:inorganic phosphate antiporter activity" EXACT [] xref: GO:0051407 is_a: CCO:F0002761 ! organophosphate:inorganic phosphate antiporter activity [Term] id: CCO:F0008102 name: glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out)." [GOC:ai] xref: GO:0051408 is_a: CCO:F0002761 ! organophosphate:inorganic phosphate antiporter activity [Term] id: CCO:F0008103 name: ALP binding namespace: molecular_function def: "Interacting selectively wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band." [PMID:11699871] synonym: "actinin-associated LIM protein binding" EXACT [] xref: GO:0051411 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0008104 name: myotilin binding namespace: molecular_function def: "Interacting selectively with myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C." [PMID:11699871, PMID:15752755] xref: GO:0051416 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0008105 name: nebulin binding namespace: molecular_function def: "Interacting selectively with nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone." [PMID:11699871] xref: GO:0051419 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0008106 name: nebulette binding namespace: molecular_function def: "Interacting selectively with nebulette, a 107 kDa protein associated with the I-Z-I complex of cardiac myofibrils. It shows a high degree of homology with skeletal muscle nebulin." [PMID:11699871] xref: GO:0051420 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0008107 name: corticotropin-releasing hormone binding namespace: molecular_function def: "Interacting selectively with corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland." [http://www.onelook.com] synonym: "corticoliberin binding" EXACT [] synonym: "corticotropin-releasing factor binding" EXACT [] synonym: "CRH binding" EXACT [] xref: GO:0051424 is_a: CCO:F0003529 ! peptide hormone binding [Term] id: CCO:F0008108 name: PTB domain binding namespace: molecular_function def: "Interacting selectively with a phosphotyrosine-binding (PTB) domain of a protein." [Pfam:PF02174.5, PMID:15924411] synonym: "phosphotyrosine-interacting domain binding" EXACT [] synonym: "PID binding" BROAD [] xref: GO:0051425 is_a: CCO:F0004213 ! protein domain specific binding [Term] id: CCO:F0008109 name: hormone receptor binding namespace: molecular_function def: "Interacting selectively with a receptor for hormones." [GOC:ai] xref: GO:0051427 is_a: CCO:F0001407 ! receptor binding [Term] id: CCO:F0008110 name: peptide hormone receptor binding namespace: molecular_function def: "Interacting selectively with a receptor for peptide hormones." [GOC:ai] synonym: "polypeptide hormone receptor binding" EXACT [] xref: GO:0051428 is_a: CCO:F0008109 ! hormone receptor binding [Term] id: CCO:F0008111 name: corticotropin-releasing hormone receptor binding namespace: molecular_function def: "Interacting selectively with a receptor for corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland." [GOC:ai] xref: GO:0051429 is_a: CCO:F0008110 ! peptide hormone receptor binding [Term] id: CCO:F0008112 name: corticotropin-releasing hormone receptor 1 binding namespace: molecular_function def: "Interacting selectively with the protein corticotropin-releasing hormone receptor 1 (CRHR1). The CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on adrenocorticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system." [PMID:15134857] synonym: "CRHR1 binding" EXACT [] xref: GO:0051430 is_a: CCO:F0008111 ! corticotropin-releasing hormone receptor binding [Term] id: CCO:F0008113 name: corticotropin-releasing hormone receptor 2 binding namespace: molecular_function def: "Interacting selectively with the protein corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery." [PMID:15134857] synonym: "CRHR2 binding" EXACT [] xref: GO:0051431 is_a: CCO:F0008111 ! corticotropin-releasing hormone receptor binding [Term] id: CCO:F0008114 name: BH1 domain binding namespace: molecular_function def: "Interacting selectively with the BH1 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01080] xref: GO:0051432 is_a: CCO:F0008096 ! BH domain binding [Term] id: CCO:F0008115 name: BH2 domain binding namespace: molecular_function def: "Interacting selectively with the BH2 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01258] xref: GO:0051433 is_a: CCO:F0008096 ! BH domain binding [Term] id: CCO:F0008116 name: BH3 domain binding namespace: molecular_function def: "Interacting selectively with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01259] xref: GO:0051434 is_a: CCO:F0008096 ! BH domain binding [Term] id: CCO:F0008117 name: BH4 domain binding namespace: molecular_function def: "Interacting selectively with the BH4 domain of a protein of the Bcl-2 family. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein." [InterPro:IPR003093, PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409, Prosite:PS01260, Prosite:PS50063] xref: GO:0051435 is_a: CCO:F0008096 ! BH domain binding [Term] id: CCO:F0008118 name: gonadotropin-releasing hormone binding namespace: molecular_function def: "Interacting selectively with gonadotropin-releasing hormone, a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary and it is synthesized and released by the hypothalamus." [PMID:1984190] synonym: "gonadotrophin-releasing hormone binding" EXACT [] xref: GO:0051448 is_a: CCO:F0003529 ! peptide hormone binding [Term] id: CCO:F0008119 name: thyrotropin-releasing hormone binding namespace: molecular_function def: "Interacting selectively with thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system." [GOC:ai] xref: GO:0051449 is_a: CCO:F0003529 ! peptide hormone binding [Term] id: CCO:F0008120 name: ectoine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of ectoine from one side of the membrane to the other. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria." [GOC:ai] subset: gosubset_prok xref: GO:0051471 is_a: CCO:F0001683 ! monocarboxylic acid transmembrane transporter activity [Term] id: CCO:F0008121 name: glucosylglycerol transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a glucosylglycerol from one side of the membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: GO:0051474 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0008122 name: mannosylglycerate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a mannosylglycerate from one side of the membrane to the other." [GOC:ai, PMID:15034926] xref: GO:0051477 is_a: CCO:F0002621 ! carbohydrate transmembrane transporter activity [Term] id: CCO:F0008123 name: syn-copalyl diphosphate synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranylgeranyl diphosphate = syn-copalyl diphosphate." [MetaCyc:RXN-4861] synonym: "diterpene cyclase activity" BROAD [] xref: GO:0051498 xref: MetaCyc:RXN-4861 is_a: CCO:F0003432 ! intramolecular lyase activity [Term] id: CCO:F0008124 name: D-aminoacyl-tRNA deacylase activity namespace: molecular_function def: "Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA." [PMID:14527667] xref: GO:0051499 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0008125 name: D-tyrosyl-tRNA(Tyr) deacylase activity namespace: molecular_function def: "Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine resides in charged tRNA." [PMID:14527667] xref: GO:0051500 is_a: CCO:F0008124 ! D-aminoacyl-tRNA deacylase activity [Term] id: CCO:F0008126 name: cholesterol UDP-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-cholesterol." [GOC:ai] xref: GO:0051505 is_a: CCO:F0003462 ! sterol 3-beta-glucosyltransferase activity [Term] id: CCO:F0008127 name: ergosterol UDP-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-ergosterol." [GOC:ai] xref: GO:0051506 is_a: CCO:F0003462 ! sterol 3-beta-glucosyltransferase activity [Term] id: CCO:F0008128 name: beta-sitosterol UDP-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-beta-sitosterol." [GOC:ai] xref: GO:0051507 is_a: CCO:F0003462 ! sterol 3-beta-glucosyltransferase activity [Term] id: CCO:F0008129 name: stigmasterol UDP-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-stigmasterol." [GOC:ai] xref: GO:0051508 is_a: CCO:F0003462 ! sterol 3-beta-glucosyltransferase activity [Term] id: CCO:F0008130 name: tomatidine UDP-glucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-tomatidine." [GOC:ai] xref: GO:0051509 is_a: CCO:F0003462 ! sterol 3-beta-glucosyltransferase activity [Term] id: CCO:F0008131 name: NFAT protein binding namespace: molecular_function def: "Interacting selectively with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system." [PMID:15928679] synonym: "NFAT binding" EXACT [] synonym: "nuclear factor of activated T cell protein binding" EXACT [] xref: GO:0051525 is_a: CCO:F0001738 ! transcription factor binding [Term] id: CCO:F0008132 name: NFAT1 protein binding namespace: molecular_function def: "Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a calcium-regulated protein which acts as a transcription factor." [GOC:ai] synonym: "NFATc2 binding" EXACT [] synonym: "NFATp binding" EXACT [] xref: GO:0051526 is_a: CCO:F0008131 ! NFAT protein binding [Term] id: CCO:F0008133 name: NFAT2 protein binding namespace: molecular_function def: "Interacting selectively with NFAT2 (nuclear factor of activated T cells 2 protein), a calcium-regulated protein which acts as a transcription factor." [GOC:ai] synonym: "NFATc binding" EXACT [] synonym: "NFATc1 binding" EXACT [] xref: GO:0051527 is_a: CCO:F0008131 ! NFAT protein binding [Term] id: CCO:F0008134 name: NFAT3 protein binding namespace: molecular_function def: "Interacting selectively with NFAT3 (nuclear factor of activated T cells 3 protein), a calcium-regulated protein which acts as a transcription factor." [GOC:ai] synonym: "NFATc4 binding" EXACT [] xref: GO:0051528 is_a: CCO:F0008131 ! NFAT protein binding [Term] id: CCO:F0008135 name: NFAT4 protein binding namespace: molecular_function def: "Interacting selectively with NFAT4 (nuclear factor of activated T cells 4 protein), a calcium-regulated protein which acts as a transcription factor." [GOC:ai] synonym: "NFATc3 binding" RELATED [] synonym: "NFATx binding" EXACT [] xref: GO:0051529 is_a: CCO:F0008131 ! NFAT protein binding [Term] id: CCO:F0008136 name: NFAT5 protein binding namespace: molecular_function def: "Interacting selectively with NFAT1 (nuclear factor of activated T cells 1 protein), a member of the NFAT transcription factor family which is not calcium regulated." [GOC:ai] synonym: "non-calcium-regulated NFAT protein binding" EXACT [] xref: GO:0051530 is_a: CCO:F0008131 ! NFAT protein binding [Term] id: CCO:F0008137 name: syntaxin-5 binding namespace: molecular_function def: "Interacting selectively with the SNAP receptor syntaxin-5." [GOC:ai, PMID:12388752] xref: GO:0051535 is_a: CCO:F0004214 ! syntaxin binding [Term] id: CCO:F0008138 name: iron-sulfur cluster binding namespace: molecular_function def: "Interacting selectively with an iron-sulfur cluster, a combination of iron and sulfur atoms." [GOC:ai] synonym: "Fe/S binding" EXACT [] synonym: "iron sulfur cluster binding" EXACT [] synonym: "iron sulphur cluster binding" EXACT [] synonym: "iron-sulphur cluster binding" EXACT [] xref: GO:0051536 is_a: CCO:F0008142 ! metal cluster binding [Term] id: CCO:F0008139 name: 2 iron, 2 sulfur cluster binding namespace: molecular_function def: "Interacting selectively with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands." [GOC:ai, http://en.wikipedia.org/wiki/Iron-sulfur_cluster] synonym: "2 Fe 2 S cluster binding" EXACT [] synonym: "2 iron, 2 sulphur cluster binding" EXACT [] synonym: "2Fe-2S cluster binding" EXACT [] synonym: "diiron disulfide cluster binding" EXACT [] synonym: "diiron disulphide cluster binding" EXACT [] synonym: "iron-sulfur cluster 2Fe-2S binding" EXACT [] synonym: "iron-sulphur cluster 2Fe-2S binding" EXACT [] xref: GO:0051537 is_a: CCO:F0008138 ! iron-sulfur cluster binding [Term] id: CCO:F0008140 name: 3 iron, 4 sulfur cluster binding namespace: molecular_function def: "Interacting selectively with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing." [GOC:ai, http://en.wikipedia.org/wiki/Iron-sulfur_cluster] synonym: "3 Fe 4 S cluster binding" EXACT [] synonym: "3 iron, 4 sulphur cluster binding" EXACT [] synonym: "3Fe-4S cluster binding" EXACT [] synonym: "iron-sulfur cluster 3Fe-4S binding" EXACT [] synonym: "iron-sulphur cluster 3Fe-4S binding" EXACT [] synonym: "triiron tetrasulfide cluster binding" EXACT [] synonym: "triiron tetrasulphide cluster binding" EXACT [] xref: GO:0051538 is_a: CCO:F0008138 ! iron-sulfur cluster binding [Term] id: CCO:F0008141 name: 4 iron, 4 sulfur cluster binding namespace: molecular_function def: "Interacting selectively with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands." [GOC:ai, http://en.wikipedia.org/wiki/Iron-sulfur_cluster] synonym: "4 Fe 4 S cluster binding" EXACT [] synonym: "4 iron, 4 sulphur cluster binding" EXACT [] synonym: "4Fe-4S cluster binding" EXACT [] synonym: "iron-sulfur cluster 4Fe-4S binding" EXACT [] synonym: "iron-sulphur cluster 4Fe-4S binding" EXACT [] synonym: "tetrairon tetrasulfide cluster binding" EXACT [] synonym: "tetrairon tetrasulphide cluster binding" EXACT [] xref: GO:0051539 is_a: CCO:F0008138 ! iron-sulfur cluster binding [Term] id: CCO:F0008142 name: metal cluster binding namespace: molecular_function def: "Interacting selectively with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters." [GOC:jsg] subset: goslim_pir subset: gosubset_prok xref: GO:0051540 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008143 name: anthocyanidin-3-glucoside rhamnosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP." [PMID:8130800] synonym: "3RT activity" BROAD [] synonym: "anthocyanidin 3-glucoside-rhamnosyltransferase activity" EXACT [] xref: GO:0051566 is_a: CCO:F0003333 ! transferase activity, transferring hexosyl groups [Term] id: CCO:F0008144 name: 5'-deoxyribose-5-phosphate lyase activity namespace: molecular_function def: "Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site." [PMID:11251121, PMID:16120966] synonym: "5'-deoxyribose phosphate activity" EXACT [] synonym: "dRP lyase activity" BROAD [] synonym: "dRPase activity" BROAD [] xref: GO:0051575 is_a: CCO:F0003401 ! carbon-oxygen lyase activity [Term] id: CCO:F0008145 name: Myf5 binding namespace: molecular_function def: "Interacting selectively with the muscle regulatory factor Myf5." [GOC:ai] xref: GO:0051576 is_a: CCO:F0005854 ! MRF binding [Term] id: CCO:F0008146 name: MyoD binding namespace: molecular_function def: "Interacting selectively with the muscle regulatory factor MyoD." [GOC:ai] xref: GO:0051577 is_a: CCO:F0005854 ! MRF binding [Term] id: CCO:F0008147 name: Mrf4 binding namespace: molecular_function def: "Interacting selectively with the muscle regulatory factor Mrf4." [GOC:ai] xref: GO:0051578 is_a: CCO:F0005854 ! MRF binding [Term] id: CCO:F0008148 name: myogenin binding namespace: molecular_function def: "Interacting selectively with the muscle regulatory factor myogenin." [GOC:ai] xref: GO:0051579 is_a: CCO:F0005854 ! MRF binding [Term] id: CCO:F0008149 name: bacterial cell surface binding namespace: molecular_function def: "Interacting selectively with any component on the surface of a bacterial cell." [GOC:ai] subset: gosubset_prok synonym: "bacterium cell surface binding" EXACT [] xref: GO:0051635 is_a: CCO:F0001847 ! bacterial binding is_a: CCO:F0005862 ! cell surface binding [Term] id: CCO:F0008150 name: Gram-negative bacterial cell surface binding namespace: molecular_function def: "Interacting selectively with any component on the surface of a Gram-negative bacterial cell." [GOC:ai] subset: gosubset_prok synonym: "Gram-negative bacterium cell surface binding" EXACT [] xref: GO:0051636 is_a: CCO:F0001848 ! Gram-negative bacterial binding is_a: CCO:F0008149 ! bacterial cell surface binding [Term] id: CCO:F0008151 name: Gram-positive bacterial cell surface binding namespace: molecular_function def: "Interacting selectively with any component on the surface of a Gram-positive bacterium." [GOC:ai] subset: gosubset_prok synonym: "Gram-positive bacterium cell surface binding" EXACT [] xref: GO:0051637 is_a: CCO:F0008054 ! Gram-positive bacterial binding is_a: CCO:F0008149 ! bacterial cell surface binding [Term] id: CCO:F0008152 name: fructan beta-fructosidase activity namespace: molecular_function def: "Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans." [EC:3.2.1.80] synonym: "beta-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.80] synonym: "exo-beta-D-fructosidase activity" EXACT [] synonym: "exo-beta-fructosidase activity" EXACT [] synonym: "fructan b-fructosidase activity" EXACT [] synonym: "fructan exohydrolase activity" EXACT [] synonym: "fructanase activity" EXACT [EC:3.2.1.80] synonym: "polysaccharide beta-fructofuranosidase activity" EXACT [] xref: EC:3.2.1.80 xref: GO:0051669 xref: MetaCyc:3.2.1.80-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0008153 name: inulinase activity namespace: molecular_function def: "Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin." [EC:3.2.1.7] synonym: "2,1-beta-D-fructan fructanohydrolase activity" EXACT [] synonym: "endo-inulinase activity" EXACT [] synonym: "exoinulinase activity" EXACT [] synonym: "indoinulinase activity" EXACT [] synonym: "inulase activity" EXACT [] xref: EC:3.2.1.7 xref: GO:0051670 xref: MetaCyc:3.2.1.7-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0008154 name: isopullulanase activity namespace: molecular_function def: "Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose)." [EC:3.2.1.57] synonym: "pullulan 4-glucanohydrolase (isopanose-forming) activity" EXACT [] xref: EC:3.2.1.57 xref: GO:0051675 xref: MetaCyc:3.2.1.57-RXN is_a: CCO:F0000939 ! hydrolase activity, hydrolyzing O-glycosyl compounds [Term] id: CCO:F0008155 name: saccharopine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2." [PMID:16233628] synonym: "SAX activity" BROAD [] xref: GO:0051698 is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0008156 name: proline oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2." [MetaCyc:RXN-821] xref: EC:1.5.3.- xref: GO:0051699 xref: MetaCyc:RXN-821 is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0008157 name: fructosyl-amino acid oxidase activity namespace: molecular_function def: "Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2." [PMID:16233628] synonym: "FAOD activity" EXACT [] xref: EC:1.5.3.- xref: GO:0051700 is_a: CCO:F0003246 ! oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor [Term] id: CCO:F0008158 name: inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate." [GOC:bf, MetaCyc:3.1.3.62-RXN] synonym: "inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity" EXACT [EC:2.7.1.-] synonym: "inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity" EXACT [EC:2.7.1.-] synonym: "inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity" EXACT [EC:2.7.1.-] xref: GO:0051717 xref: MetaCyc:3.1.3.62-RXN is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0008159 name: DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpG." [EC:2.1.1.37, PMID:15689527] synonym: "HpaII methylase" NARROW [EC:2.1.1.37] synonym: "HpaII' methylase" NARROW [EC:2.1.1.37] synonym: "M.BsuRIa" NARROW [EC:2.1.1.37] synonym: "M.BsuRIb" NARROW [EC:2.1.1.37] xref: GO:0051718 is_a: CCO:F0000405 ! DNA (cytosine-5-)-methyltransferase activity [Term] id: CCO:F0008160 name: DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN." [EC:2.1.1.37, PMID:15689527] xref: GO:0051719 is_a: CCO:F0000405 ! DNA (cytosine-5-)-methyltransferase activity [Term] id: CCO:F0008161 name: DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG." [EC:2.1.1.37, PMID:15689527] xref: GO:0051720 is_a: CCO:F0000405 ! DNA (cytosine-5-)-methyltransferase activity [Term] id: CCO:F0008162 name: protein phosphatase 2A binding namespace: molecular_function def: "Interacting selectively with the enzyme protein phosphatase 2A." [GOC:ai] xref: GO:0051721 is_a: CCO:F0004212 ! protein phosphatase binding [Term] id: CCO:F0008163 name: protein C-terminal methylesterase activity namespace: molecular_function def: "Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol." [PMID:10318862, PMID:8650216] synonym: "protein phosphatase methylesterase activity" NARROW [] xref: GO:0051722 is_a: CCO:F0008164 ! protein methylesterase activity [Term] id: CCO:F0008164 name: protein methylesterase activity namespace: molecular_function def: "Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol." [GOC:ai] subset: gosubset_prok synonym: "PME activity" EXACT [EC:2.7.1.-] synonym: "protein carboxyl methylesterase activity" EXACT [EC:2.7.1.-] synonym: "protein carboxylic ester hydrolase activity" EXACT [] synonym: "protein methyl-esterase activity" EXACT [EC:2.7.1.-] xref: GO:0051723 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0008165 name: NAD transporter activity namespace: molecular_function def: "Enables the directed movement of nicotinamide adenine dinucleotide into, out of, within or between cells; transport may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:ai] synonym: "NAD (oxidized) transporter activity" EXACT [] synonym: "NAD (reduced) transporter activity" EXACT [] synonym: "NAD+ transporter activity" EXACT [] synonym: "NADH transporter activity" EXACT [] synonym: "nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT [] synonym: "oxidized NAD transporter activity" EXACT [] synonym: "oxidized nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT [] synonym: "reduced NAD transporter activity" EXACT [] synonym: "reduced nicotinamide adenine dinucleotide transmembrane transporter activity" EXACT [] xref: GO:0051724 is_a: CCO:F0008066 ! cofactor transporter activity [Term] id: CCO:F0008166 name: GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA." [EC:2.7.1.78, PMID:8428918] synonym: "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] synonym: "GTP-dependent polyribonucleotide kinase activity" EXACT [] synonym: "GTP-dependent RNA 5'-hydroxyl-kinase activity" EXACT [] synonym: "GTP-dependent RNA kinase activity" EXACT [] synonym: "GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity" EXACT [] xref: GO:0051730 is_a: CCO:F0008168 ! polyribonucleotide kinase activity is_a: CCO:F0008171 ! GTP-dependent polynucleotide kinase activity [Term] id: CCO:F0008167 name: polynucleotide kinase activity namespace: molecular_function def: "Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA." [EC:2.7.1.78] synonym: "5'-dephosphopolynucleotide kinase activity" EXACT [] synonym: "5'-hydroxyl polynucleotide kinase activity" EXACT [EC:2.7.1.78] synonym: "PNK" RELATED [EC:2.7.1.78] synonym: "polynucleotide 5'-hydroxy-kinase activity" EXACT [EC:2.7.1.78] synonym: "polynucleotide 5'-hydroxyl kinase (phosphorylating) activity" EXACT [EC:2.7.1.78] synonym: "polynucleotide 5'-hydroxyl-kinase activity" EXACT [EC:2.7.1.78] xref: EC:2.7.1.- xref: GO:0051731 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0008168 name: polyribonucleotide kinase activity namespace: molecular_function def: "Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA." [EC:2.7.1.78] synonym: "5'-hydroxyl polyribonucleotide kinase activity" EXACT [EC:2.7.1.78] synonym: "5'-hydroxyl RNA kinase activity" EXACT [EC:2.7.1.78] synonym: "RNA 5'-hydroxyl kinase activity" EXACT [] synonym: "RNA kinase activity" EXACT [] xref: GO:0051732 is_a: CCO:F0008167 ! polynucleotide kinase activity [Term] id: CCO:F0008169 name: polydeoxyribonucleotide kinase activity namespace: molecular_function def: "Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA." [EC:2.7.1.78] synonym: "DNA 5'-hydroxyl kinase activity" EXACT [] synonym: "DNA kinase activity" EXACT [] xref: GO:0051733 is_a: CCO:F0008167 ! polynucleotide kinase activity [Term] id: CCO:F0008170 name: ATP-dependent polynucleotide kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA." [EC:2.7.1.78] synonym: "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity" EXACT [] synonym: "ATP:5'-dephosphopolynucleotide 5'-phosphatase activity" EXACT [EC:2.7.1.78] synonym: "ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity" EXACT [] xref: EC:2.7.1.- xref: GO:0051734 is_a: CCO:F0008167 ! polynucleotide kinase activity [Term] id: CCO:F0008171 name: GTP-dependent polynucleotide kinase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA." [EC:2.7.1.78] synonym: "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity" EXACT [] synonym: "GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity" EXACT [] xref: EC:2.7.1.- xref: GO:0051735 is_a: CCO:F0008167 ! polynucleotide kinase activity [Term] id: CCO:F0008172 name: ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA." [EC:2.7.1.78] synonym: "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] synonym: "ATP-dependent polyribonucleotide kinase activity" EXACT [] synonym: "ATP-dependent RNA 5'-hydroxyl-kinase activity" EXACT [] synonym: "ATP-dependent RNA kinase activity" EXACT [] synonym: "ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity" EXACT [] xref: GO:0051736 is_a: CCO:F0008168 ! polyribonucleotide kinase activity is_a: CCO:F0008170 ! ATP-dependent polynucleotide kinase activity [Term] id: CCO:F0008173 name: GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity namespace: molecular_function def: "Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA." [EC:2.7.1.78, PMID:8428918] synonym: "GTP-dependent DNA 5'-hydroxyl-kinase activity" EXACT [] synonym: "GTP-dependent DNA kinase activity" EXACT [] synonym: "GTP-dependent polydeoxyribonucleotide kinase activity" EXACT [] synonym: "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity" BROAD [] synonym: "GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity" EXACT [] xref: GO:0051737 is_a: CCO:F0008169 ! polydeoxyribonucleotide kinase activity is_a: CCO:F0008171 ! GTP-dependent polynucleotide kinase activity [Term] id: CCO:F0008174 name: xanthophyll binding namespace: molecular_function def: "Interacting selectively with xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen." [ISBN:0122146743] xref: GO:0051738 is_a: CCO:F0004189 ! isoprenoid binding is_a: CCO:F0004661 ! pigment binding [Term] id: CCO:F0008175 name: ammonia transporter activity namespace: molecular_function def: "Enables the directed movement of ammonia into, out of, within or between cells." [GOC:go_curators] subset: gosubset_prok xref: GO:0051739 is_a: CCO:F0004311 ! substrate-specific transporter activity [Term] id: CCO:F0008176 name: ethylene binding namespace: molecular_function def: "Interacting selectively with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator." [GOC:ai] synonym: "ethene binding" EXACT [] xref: GO:0051740 is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0008177 name: 2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine." [MetaCyc:RXN-2542] synonym: "MPBQ methyltransferase activity" EXACT [] xref: GO:0051741 xref: MetaCyc:RXN-2542 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008178 name: 2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine." [MetaCyc:RXN-2762] synonym: "MSBQ methyltransferase activity" EXACT [] xref: GO:0051742 xref: MetaCyc:RXN-2762 is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008179 name: red chlorophyll catabolite reductase activity namespace: molecular_function def: "Catalysis of the reaction: red chlorophyll catabolite (RCC) + reduced ferredoxin + 2 H+ = primary fluorescent catabolite (pFCC) + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite to a colorless tetrapyrrole with a strong blue fluorescence." [PMID:10743659] synonym: "RCC reductase activity" EXACT [] xref: EC:1.3.7.- xref: GO:0051743 is_a: CCO:F0003237 ! oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor [Term] id: CCO:F0008180 name: 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity namespace: molecular_function def: "Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+." [MetaCyc:RXN1F-72] xref: GO:0051744 xref: MetaCyc:RXN1F-72 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008181 name: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity namespace: molecular_function def: "Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate." [EC:1.17.1.2] synonym: "4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity" EXACT [EC:1.17.1.2] synonym: "isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity" EXACT [] xref: EC:1.17.1.2 xref: GO:0051745 xref: MetaCyc:1.17.1.2-RXN is_a: CCO:F0003308 ! oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor [Term] id: CCO:F0008182 name: thalianol synthase activity namespace: molecular_function def: "Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol)." [PMID:15125655] xref: GO:0051746 is_a: CCO:F0004686 ! oxidosqualene cyclase activity [Term] id: CCO:F0008183 name: DNA demethylase activity namespace: molecular_function def: "Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA." [PMID:10050851] xref: GO:0051747 is_a: CCO:F0003359 ! hydrolase activity is_a: CCO:F0004997 ! demethylase activity [Term] id: CCO:F0008184 name: UTP-monosaccharide-1-phosphate uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide." [EC:2.7.7.64, PMID:15326166] subset: gosubset_prok synonym: "PsUSP" RELATED [EC:2.7.7.64] synonym: "UDP-monosaccharide diphosphorylase activity" EXACT [] synonym: "UDP-monosaccharide pyrophosphorylase activity" EXACT [] synonym: "UDP-sugar pyrophosphorylase activity" EXACT [EC:2.7.7.64] synonym: "USP" RELATED [EC:2.7.7.64] xref: EC:2.7.7.64 xref: GO:0051748 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0008185 name: indole acetic acid carboxyl methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine." [PMID:16169896] synonym: "IAA carboxyl methyltransferase activity" EXACT [] xref: GO:0051749 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0008186 name: delta3,5-delta2,4-dienoyl-CoA isomerase activity namespace: molecular_function def: "Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA." [PMID:16040662] xref: GO:0051750 is_a: CCO:F0003425 ! intramolecular oxidoreductase activity, transposing C=C bonds [Term] id: CCO:F0008187 name: alpha-1,4-mannosyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,4-linkage." [PMID:15772281] xref: GO:0051751 is_a: CCO:F0000008 ! mannosyltransferase activity [Term] id: CCO:F0008188 name: phosphoglucan, water dikinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate." [EC:2.7.9.5, PMID:15618411] synonym: "ATP:phospho-alpha-glucan, water phosphotransferase activity" EXACT [EC:2.7.9.5] synonym: "OK1" RELATED [EC:2.7.9.5] synonym: "PWD" RELATED [EC:2.7.9.5] xref: EC:2.7.9.5 xref: GO:0051752 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003353 ! phosphotransferase activity, paired acceptors [Term] id: CCO:F0008189 name: mannan synthase activity namespace: molecular_function def: "Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-1,4-linked mannan backbone in substrates such as galactomannan." [PMID:14726589] synonym: "galactomannan beta-1,4-mannosyltransferase activity" NARROW [] synonym: "mannan beta-1,4-mannosyltransferase activity" EXACT [] xref: GO:0051753 is_a: CCO:F0004117 ! beta-1,4-mannosyltransferase activity [Term] id: CCO:F0008190 name: inositol tetrakisphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP." [GOC:ai] xref: GO:0051765 is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0008191 name: inositol trisphosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP." [GOC:ai] xref: GO:0051766 is_a: CCO:F0000836 ! inositol or phosphatidylinositol kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0008192 name: ent-kaurenoate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)." [EC:1.14.13.79, MetaCyc:RXN1F-159] comment: Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'. synonym: "ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity" EXACT [EC:1.14.13.79] synonym: "ent-kaurenoic acid oxidase activity" EXACT [] xref: GO:0051777 xref: MetaCyc:RXN1F-159 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008193 name: ent-7-alpha-hydroxykaurenoate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)." [EC:1.14.13.79, MetaCyc:RXN1F-160] comment: Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'. xref: GO:0051778 xref: MetaCyc:RXN1F-160 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008194 name: gibberellin 12-aldehyde oxidase activity namespace: molecular_function def: "Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + O2 = gibberellin 12 (GA12) + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)." [EC:1.14.13.79, MetaCyc:RXN1F-161] comment: Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778'. synonym: "GA12-aldehyde oxidase activity" EXACT [] xref: GO:0051779 xref: MetaCyc:RXN1F-161 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008195 name: all-trans-retinol 13,14-reductase activity namespace: molecular_function def: "Catalysis of the reaction: all-trans-13,14-dihydroretinol + acceptor = all-trans-retinol + reduced acceptor. Note that this reaction has only been observed to occur in the opposite direction." [EC:1.3.99.23] synonym: "(13,14)-all-trans-retinol saturase activity" EXACT [] synonym: "all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity" EXACT [] synonym: "all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity" EXACT [] synonym: "retinol saturase activity" EXACT [EC:1.3.99.23] synonym: "RetSat activity" EXACT [EC:1.3.99.23] xref: EC:1.3.99.23 xref: GO:0051786 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0008196 name: misfolded protein binding namespace: molecular_function def: "Interacting selectively with a misfolded protein." [GOC:ai] xref: GO:0051787 is_a: CCO:F0001646 ! protein binding [Term] id: CCO:F0008197 name: phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidyl inositol-4-phosphate + phosphate." [GOC:bf, PMID:9811831] synonym: "PTEN activity" BROAD [] xref: GO:0051800 is_a: CCO:F0005684 ! lipid phosphatase activity is_a: CCO:F0008466 ! phosphatidylinositol bisphosphate phosphatase activity [Term] id: CCO:F0008198 name: glycolipid binding namespace: molecular_function def: "Interacting selectively with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic moiety such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate." [http://www.chem.qmul.ac.uk/iupac/misc/glylp.html] xref: GO:0051861 is_a: CCO:F0001816 ! lipid binding [Term] id: CCO:F0008199 name: histone demethylase activity (H3-K36 specific) namespace: molecular_function def: "Catalysis of the reaction: methyl-lysine + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. The methyl-lysine residue is at position 36 of histone 3." [PMID:16362057] synonym: "[histone-H3]-lysine-36 demethylase activity" EXACT [] synonym: "H3-K36-specific demethylase activity" EXACT [EC:1.14.11.27] synonym: "histone H3-lysine-36 demethylase activity" EXACT [EC:1.14.11.27] synonym: "histone-lysine (H3-K36) demethylase activity" EXACT [EC:1.14.11.27] synonym: "histone-lysine demethylase activity (H3-K36 specific)" EXACT [] synonym: "histone-lysine(H3-K36) demethylase activity" EXACT [] synonym: "JHDM1A activity" NARROW [EC:1.14.11.27] synonym: "JmjC domain-containing histone demethylase 1A activity" NARROW [EC:1.14.11.27] synonym: "protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.27] synonym: "protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.27] xref: EC:1.14.11.27 xref: GO:0051864 is_a: CCO:F0003289 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors is_a: CCO:F0004998 ! histone demethylase activity [Term] id: CCO:F0008200 name: methotrexate binding namespace: molecular_function def: "Interacting selectively with methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA." [GOC:nln] subset: gosubset_prok xref: GO:0051870 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008201 name: dihydrofolic acid binding namespace: molecular_function def: "Interacting selectively with dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] synonym: "DHF binding" RELATED [] synonym: "dihydrofolate binding" RELATED [] xref: GO:0051871 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008202 name: Hsp90 protein binding namespace: molecular_function def: "Interacting selectively with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size." [GOC:ai] synonym: "Hsp90 binding" EXACT [] synonym: "Hsp90 class protein binding" EXACT [] xref: GO:0051879 is_a: CCO:F0004628 ! heat shock protein binding [Term] id: CCO:F0008203 name: G-quadruplex DNA binding namespace: molecular_function def: "Interacting selectively with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome." [PMID:16142245, PMID:9512530] synonym: "G-DNA binding" EXACT [] synonym: "G-quartet binding" EXACT [] synonym: "quadruplex DNA binding" EXACT [] synonym: "tetraplex DNA binding" EXACT [] xref: GO:0051880 is_a: CCO:F0005878 ! structure-specific DNA binding [Term] id: CCO:F0008204 name: S-(hydroxymethyl)glutathione dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+." [EC:1.1.1.284] synonym: "ADH3 activity" NARROW [EC:1.1.1.284] synonym: "chi-ADH activity" NARROW [EC:1.1.1.284] synonym: "class III alcohol dehydrogenase activity" RELATED [EC:1.1.1.284] synonym: "FDH activity" RELATED [EC:1.1.1.284] synonym: "formic dehydrogenase activity" RELATED [EC:1.1.1.284] synonym: "GD-FALDH activity" EXACT [EC:1.1.1.284] synonym: "glutathione-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] synonym: "GS-FDH activity" EXACT [EC:1.1.1.284] synonym: "NAD- and glutathione-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] synonym: "NAD-dependent formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] synonym: "NAD-linked formaldehyde dehydrogenase activity" EXACT [EC:1.1.1.284] synonym: "S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.284] xref: EC:1.1.1.284 xref: GO:0051903 xref: MetaCyc:RXN-2962 xref: UM-BBD_enzymeID:e0709 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008205 name: S-(hydroxymethyl)glutathione synthase activity namespace: molecular_function def: "Catalysis of the reaction: S-(hydroxymethyl)glutathione = glutathione + formaldehyde." [EC:4.4.1.22] synonym: "Gfa" RELATED [EC:4.4.1.22] synonym: "glutathione-dependent formaldehyde-activating enzyme activity" EXACT [] synonym: "S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)" EXACT [EC:4.4.1.22] synonym: "S-(hydroxymethyl)glutathione formaldehyde-lyase activity" EXACT [EC:4.4.1.22] xref: EC:4.4.1.22 xref: GO:0051907 xref: MetaCyc:RXN-2961 xref: UM-BBD_enzymeID:e0710 is_a: CCO:F0003410 ! carbon-sulfur lyase activity [Term] id: CCO:F0008206 name: double-stranded DNA specific 5'-3' exodeoxyribonuclease activity namespace: molecular_function def: "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule." [GOC:ai] xref: GO:0051908 is_a: CCO:F0001823 ! double-stranded DNA specific exodeoxyribonuclease activity is_a: CCO:F0005595 ! 5'-3' exodeoxyribonuclease activity [Term] id: CCO:F0008207 name: acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O." [MetaCyc:ACETYLENECARBOXYLATE-HYDRATASE-RXN] synonym: "3-hydroxypropenoate dehydratase activity" EXACT [] synonym: "acetylenecarboxylate hydratase activity" BROAD [] synonym: "acetylenemonocarboxylate hydratase activity" BROAD [] synonym: "alkynoate hydratase activity" BROAD [] xref: EC:4.2.1.- xref: GO:0051909 xref: MetaCyc:ACETYLENECARBOXYLATE-HYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008208 name: heparitin sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparitin = adenosine 3',5'-bisphosphate + N-sulfoheparitin." [MetaCyc:HEPARITIN-SULFOTRANSFERASE-RXN] synonym: "heparitin N-sulfotransferase activity" EXACT [] synonym: "heparitin N-sulphotransferase activity" EXACT [] xref: GO:0051910 xref: MetaCyc:HEPARITIN-SULFOTRANSFERASE-RXN is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0008209 name: Methanosarcina-phenazine hydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine." [EC:1.12.98.3] synonym: "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity" RELATED [] synonym: "hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity" EXACT [EC:1.12.98.3] synonym: "methanophenazine hydrogenase activity" EXACT [] synonym: "methylviologen-reducing hydrogenase activity" EXACT [] xref: EC:1.12.98.3 xref: GO:0051911 xref: MetaCyc:RXN-7733 is_a: CCO:F0006309 ! oxidoreductase activity, acting on hydrogen as donor, with other known acceptors [Term] id: CCO:F0008210 name: CoB--CoM heterodisulfide reductase activity namespace: molecular_function def: "Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine." [EC:1.8.98.1] synonym: "CoB-CoM heterodisulfide reductase activity" EXACT [] synonym: "coenzyme B--coenzyme M heterodisulfide reductase activity" EXACT [] synonym: "coenzyme B:coenzyme M:methanophenazine oxidoreductase activity" EXACT [EC:1.8.98.1] synonym: "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity" RELATED [] synonym: "heterodisulfide reductase activity" BROAD [] synonym: "soluble heterodisulfide reductase activity" RELATED [EC:1.8.98.1] xref: EC:1.8.98.1 xref: GO:0051912 xref: MetaCyc:1.8.98.1-RXN is_a: CCO:F0003260 ! oxidoreductase activity, acting on sulfur group of donors [Term] id: CCO:F0008211 name: granulocyte colony-stimulating factor binding namespace: molecular_function def: "Interacting selectively with granulocyte colony-stimulating factor, G-CSF." [GOC:ai] synonym: "G-CSF binding" EXACT [] xref: GO:0051916 is_a: CCO:F0004221 ! cytokine binding [Term] id: CCO:F0008212 name: peroxiredoxin activity namespace: molecular_function def: "Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH." [EC:1.11.1.15] subset: gosubset_prok synonym: "AhpC activity" NARROW [] synonym: "alkyl hydroperoxide reductase C22 activity" NARROW [] synonym: "PRDX activity" EXACT [] synonym: "Prx activity" EXACT [] synonym: "thiol-containing-reductant:hydroperoxide oxidoreductase activity" EXACT [EC:1.11.1.15] xref: EC:1.11.1.15 xref: GO:0051920 is_a: CCO:F0000981 ! peroxidase activity [Term] id: CCO:F0008213 name: adenosylcobyric acid synthase (glutamine-hydrolyzing) activity namespace: molecular_function def: "Catalysis of the reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate." [EC:6.3.5.10] synonym: "5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity" EXACT [] synonym: "adenosylcobyric acid synthase (glutamine-hydrolysing) activity" EXACT [] synonym: "adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.10] synonym: "Ado-cobyric acid synthase [glutamine hydrolyzing] activity" EXACT [] synonym: "CobQ activity" BROAD [] synonym: "cobyric acid synthase activity" RELATED [] xref: EC:6.3.5.10 xref: GO:0051921 xref: MetaCyc:R345-RXN is_a: CCO:F0003442 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Term] id: CCO:F0008214 name: cholesterol sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate." [PMID:12730293] xref: EC:2.8.2.- xref: GO:0051922 is_a: CCO:F0000505 ! alcohol sulfotransferase activity [Term] id: CCO:F0008215 name: dynein light intermediate chain binding namespace: molecular_function def: "Interacting selectively with a light intermediate chain of the dynein complex." [GOC:bf] xref: GO:0051959 is_a: CCO:F0006133 ! dynein binding [Term] id: CCO:F0008216 name: lysophospholipid transporter activity namespace: molecular_function def: "Enables the directed movement of lysophospholipids into, out of, within or between cells. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids." [GOC:ai] subset: gosubset_prok xref: GO:0051978 is_a: CCO:F0001671 ! phospholipid transporter activity [Term] id: CCO:F0008217 name: iron-nicotianamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other." [GOC:ai] synonym: "Fe-NA chelate transporter activity" EXACT [] xref: GO:0051980 is_a: CCO:F0002966 ! iron chelate transmembrane transporter activity [Term] id: CCO:F0008218 name: copper chelate transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions." [http://www.onelook.com] subset: gosubset_prok xref: GO:0051981 is_a: CCO:F0001598 ! copper ion transmembrane transporter activity [Term] id: CCO:F0008219 name: copper-nicotianamine transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other." [GOC:ai] synonym: "Cu-NA chelate transporter activity" EXACT [] xref: GO:0051982 is_a: CCO:F0008218 ! copper chelate transmembrane transporter activity [Term] id: CCO:F0008220 name: coproporphyrinogen dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine." [EC:1.3.99.22] synonym: "coproporphyrinogen III oxidase activity" EXACT [EC:1.3.99.22] synonym: "coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)" EXACT [EC:1.3.99.22] synonym: "HemN" RELATED [EC:1.3.99.22] synonym: "oxygen-independent coproporphyrinogen-III oxidase activity" EXACT [] synonym: "radical SAM enzyme activity" RELATED [EC:1.3.99.22] xref: EC:1.3.99.22 xref: GO:0051989 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0008222 name: cyclopentanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cyclopentanol + NAD+ = cyclopentanone + NADH + H+." [EC:1.1.1.163, GOC:jic, GOC:mlg] synonym: "cyclopentanol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.163] synonym: "cyclopentanol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.163] xref: EC:1.1.1.163 xref: GO:0055041 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008223 name: 5-valerolactone hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate." [GOC:jic, GOC:mlg] xref: GO:0055042 is_a: CCO:F0006225 ! lactonohydrolase activity [Term] id: CCO:F0008224 name: 5-oxovalerate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+." [GOC:jic, GOC:mlg] xref: GO:0055043 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008225 name: mannose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+." [GOC:ct] xref: GO:0055053 is_a: CCO:F0002404 ! hexose:hydrogen symporter activity is_a: CCO:F0002958 ! mannose transmembrane transporter activity [Term] id: CCO:F0008226 name: fructose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+." [GOC:ct] xref: GO:0055054 is_a: CCO:F0001579 ! fructose transmembrane transporter activity is_a: CCO:F0002404 ! hexose:hydrogen symporter activity [Term] id: CCO:F0008227 name: D-glucose:hydrogen symporter activity namespace: molecular_function def: "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory isomer of glucose." [GOC:ct] xref: GO:0055055 is_a: CCO:F0001582 ! hydrogen:glucose symporter activity is_a: CCO:F0008228 ! D-glucose transmembrane transporter activity [Term] id: CCO:F0008228 name: D-glucose transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of the dextrorotatory isomer of the hexose monosaccharide glucose from one side of the membrane to the other." [GOC:jic] xref: GO:0055056 is_a: CCO:F0001581 ! glucose transmembrane transporter activity [Term] id: CCO:F0008229 name: gap junction hemi-channel activity namespace: molecular_function def: "A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction." [GOC:dgh] synonym: "connexon channel activity" EXACT [] xref: GO:0055077 is_a: CCO:F0004262 ! wide pore channel activity relationship: part_of CCO:F0001511 ! gap junction channel activity [Term] id: CCO:F0008230 name: adiponectin binding namespace: molecular_function def: "Interacting selectively with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism." [GOC:rl, PMID:15210937] xref: GO:0055100 is_a: CCO:F0005682 ! hormone binding [Term] id: CCO:F0008231 name: glycerophospholipase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a glycerophospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid." [GOC:ai, GOC:rl] xref: GO:0055101 is_a: CCO:F0001215 ! phospholipase inhibitor activity [Term] id: CCO:F0008232 name: lipase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid." [GOC:rl] xref: GO:0055102 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0008233 name: ligase regulator activity namespace: molecular_function def: "Modulates the activity of a ligase." [GOC:rl] xref: GO:0055103 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0008234 name: ligase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a ligase." [GOC:rl] xref: GO:0055104 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0008235 name: ubiquitin-protein ligase inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a ubiquitin-protein ligase." [GOC:rl] xref: GO:0055105 is_a: CCO:F0008234 ! ligase inhibitor activity is_a: CCO:F0008236 ! ubiquitin-protein ligase regulator activity [Term] id: CCO:F0008236 name: ubiquitin-protein ligase regulator activity namespace: molecular_function def: "Modulates the activity of a ubiquitin-protein ligase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein." [GOC:rl] xref: GO:0055106 is_a: CCO:F0008233 ! ligase regulator activity [Term] id: CCO:F0008237 name: minus-end directed microfilament motor activity namespace: molecular_function def: "Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers." [GOC:dph, PMID:10519557] synonym: "minus-end directed actin filament motor activity" RELATED [GOC:dph] synonym: "minus-end directed actin-filament motor activity" EXACT [GOC:dph] synonym: "pointed-end directed actin-filament motor activity" EXACT [GOC:dph] xref: GO:0060001 is_a: CCO:F0000026 ! microfilament motor activity [Term] id: CCO:F0008238 name: plus-end directed microfilament motor activity namespace: molecular_function def: "Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers." [GOC:dph, PMID:10519557] synonym: "barbed-end directed actin-filament motor activity" EXACT [GOC:dph] synonym: "plus-end directed actin filament motor activity" RELATED [GOC:dph] synonym: "plus-end directed actin-filament motor activity" EXACT [GOC:dph] xref: GO:0060002 is_a: CCO:F0000026 ! microfilament motor activity [Term] id: CCO:F0008239 name: large conductance calcium-activated potassium channel activity namespace: molecular_function def: "Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism." [GOC:mtg_transport, ISBN:0815340729, PMID:17115074] synonym: "BK calcium-activated potassium channel activity" EXACT [] synonym: "BK channel activity" RELATED [] synonym: "BK KCa channels" EXACT [] synonym: "large conductance KCa channels" EXACT [] xref: GO:0022895 xref: GO:0060072 is_a: CCO:F0002726 ! calcium-activated potassium channel activity [Term] id: CCO:F0008240 name: molecular transducer activity namespace: molecular_function def: "The molecular function that accepts an input of one form and creates an output of a different form." [GOC:mtg_MIT] subset: goslim_pir subset: gosubset_prok xref: GO:0060089 is_a: CCO:F0000272 ! molecular_function [Term] id: CCO:F0008241 name: molecular adaptor activity namespace: molecular_function def: "The binding activity of a molecule that brings together two or more molecules, permitting those molecules to function in a coordinated way." [GOC:mtg_MIT] subset: goslim_pir subset: gosubset_prok xref: GO:0060090 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008242 name: brain-derived neurotrophic factor receptor activity namespace: molecular_function def: "Combining with brain-derived neurotrophic factor, to block apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity." [GOC:dph] synonym: "BDNF receptor activity" RELATED [GOC:dph] xref: GO:0060175 is_a: CCO:F0001080 ! transmembrane receptor protein tyrosine kinase activity is_a: CCO:F0001357 ! neurotrophin receptor activity [Term] id: CCO:F0008243 name: apelin receptor activity namespace: molecular_function def: "Combining with the peptide apelin to initiate a change in cell activity." [GOC:dph] xref: GO:0060182 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled [Term] id: CCO:F0008244 name: phosphatidylcholine-sterol O-acyltransferase activator activity namespace: molecular_function def: "Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines." [GOC:dph, GOC:tb, PMID:4335615] synonym: "LCAT activator activity" NARROW [GOC:tb] xref: GO:0060228 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0008245 name: lipase activator activity namespace: molecular_function def: "Increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid." [GOC:dph, GOC:tb] xref: GO:0060229 is_a: CCO:F0001691 ! enzyme activator activity [Term] id: CCO:F0008246 name: lipoprotein lipase activator activity namespace: molecular_function def: "Increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein." [GOC:dph, GOC:tb, PMID:10727238] xref: GO:0060230 is_a: CCO:F0008245 ! lipase activator activity [Term] id: CCO:F0008247 name: [cytochrome c]-lysine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c." [EC:2.1.1.59] synonym: "cytochrome c (lysine) methyltransferase activity" EXACT [EC:2.1.1.59] synonym: "cytochrome c methyltransferase activity" EXACT [EC:2.1.1.59] synonym: "cytochrome c-lysine N-methyltransferase activity" EXACT [EC:2.1.1.59] synonym: "cytochrome c-specific protein methylase III activity" EXACT [EC:2.1.1.59] synonym: "cytochrome c-specific protein-lysine methyltransferase activity" EXACT [EC:2.1.1.59] synonym: "S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.59] synonym: "S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.59] xref: EC:2.1.1.59 xref: GO:0000277 xref: MetaCyc:2.1.1.59-RXN is_a: CCO:F0003100 ! protein-lysine N-methyltransferase activity [Term] id: CCO:F0008248 name: (R,R)-butanediol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+." [EC:1.1.1.4] subset: gosubset_prok synonym: "(R)-2,3-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "(R)-diacetyl reductase activity" EXACT [EC:1.1.1.4] synonym: "1-amino-2-propanol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "1-amino-2-propanol oxidoreductase activity" EXACT [EC:1.1.1.4] synonym: "2,3-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "aminopropanol oxidoreductase activity" EXACT [EC:1.1.1.4] synonym: "butylene glycol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "butyleneglycol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "D-(-)-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "D-1-amino-2-propanol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "D-1-amino-2-propanol:NAD(2) oxidoreductase activity" EXACT [EC:1.1.1.4] synonym: "D-aminopropanol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "D-butanediol dehydrogenase activity" EXACT [EC:1.1.1.4] synonym: "diacetyl (acetoin) reductase activity" RELATED [EC:1.1.1.4] xref: EC:1.1.1.4 xref: GO:0000721 xref: MetaCyc:(R is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008249 name: (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide." [EC:2.4.1.92] synonym: "asialo-GM2 synthase activity" EXACT [EC:2.4.1.92] synonym: "beta-1,4N-aetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "GalNAc-T activity" EXACT [EC:2.4.1.92] synonym: "ganglioside GM2 synthase activity" EXACT [EC:2.4.1.92] synonym: "ganglioside GM3 acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "GM2 synthase activity" EXACT [EC:2.4.1.92] synonym: "GM2/GD2-synthase activity" EXACT [EC:2.4.1.92] synonym: "UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] synonym: "uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.92] xref: EC:2.4.1.92 xref: GO:0003947 xref: MetaCyc:2.4.1.92-RXN is_a: CCO:F0001852 ! acetylgalactosaminyltransferase activity [Term] id: CCO:F0008250 name: (S)-2-hydroxy-acid oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + H2O2." [EC:1.1.3.15] subset: gosubset_prok synonym: "(S)-2-hydroxy-acid:oxygen 2-oxidoreductase" EXACT [EC:1.1.3.15] synonym: "hydroxy-acid oxidase A activity" NARROW [EC:1.1.3.15] synonym: "hydroxy-acid oxidase B activity" NARROW [EC:1.1.3.15] synonym: "hydroxyacid oxidase A" RELATED [EC:1.1.3.15] synonym: "L-2-hydroxy acid oxidase" EXACT [EC:1.1.3.15] synonym: "L-alpha-hydroxy acid oxidase" EXACT [EC:1.1.3.15] synonym: "oxidase, L-2-hydroxy acid" EXACT [EC:1.1.3.15] xref: EC:1.1.3.15 xref: GO:0003973 xref: MetaCyc:(S)-2-HYDROXY-ACID-OXIDASE-RXN is_a: CCO:F0003457 ! oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [Term] id: CCO:F0008251 name: [acyl-carrier-protein] S-acetyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein]." [EC:2.3.1.38] synonym: "[acyl-carrier protein] S-acetyltransferase activity" EXACT [] synonym: "ACAT activity" EXACT [EC:2.3.1.38] synonym: "acetyl coenzyme A-acyl-carrier-protein transacylase activity" EXACT [EC:2.3.1.38] synonym: "acetyl-CoA:acyl-carrier-protein S-acetyltransferase activity" EXACT [EC:2.3.1.38] synonym: "ACP acetyltransferase activity" EXACT [EC:2.3.1.38] synonym: "ACP S-acetyltransferase activity" EXACT [] synonym: "ACPacetyltransferase activity" EXACT [EC:2.3.1.38] synonym: "acyl-carrier-protein acetyltransferase activity" EXACT [EC:2.3.1.38] synonym: "acyl-carrier-protein S-acetyltransferase activity" EXACT [EC:2.3.1.38] synonym: "acyl-carrier-proteinacetyltransferase activity" EXACT [EC:2.3.1.38] xref: EC:2.3.1.38 xref: GO:0004313 xref: MetaCyc:ACP-S-ACETYLTRANSFER-RXN xref: Reactome:76142 is_a: CCO:F0000733 ! fatty-acid synthase activity is_a: CCO:F0003141 ! S-acetyltransferase activity [Term] id: CCO:F0008252 name: [acyl-carrier-protein] S-malonyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein]." [EC:2.3.1.39] subset: gosubset_prok synonym: "[acyl-carrier protein] S-malonyltransferase activity" EXACT [] synonym: "ACP S-malonyltransferase activity" EXACT [] synonym: "acyl carrier protein malonyltransferase activity" EXACT [EC:2.3.1.39] synonym: "acyl carrier proteinmalonyltransferase activity" EXACT [EC:2.3.1.39] synonym: "acyl-carrier-protein S-malonyltransferase activity" EXACT [EC:2.3.1.39] synonym: "FabD" RELATED [EC:2.3.1.39] synonym: "malonyl coenzyme A-acyl carrier protein transacylase activity" EXACT [EC:2.3.1.39] synonym: "malonyl transacylase activity" BROAD [EC:2.3.1.39] synonym: "malonyl transferase activity" BROAD [EC:2.3.1.39] synonym: "malonyl-CoA-acyl carrier protein transacylase activity" EXACT [EC:2.3.1.39] synonym: "malonyl-CoA:ACP transacylase activity" EXACT [EC:2.3.1.39] synonym: "malonyl-CoA:AcpM transacylase activity" EXACT [EC:2.3.1.39] synonym: "malonyl-CoA:acyl carrier protein transacylase activity" EXACT [EC:2.3.1.39] synonym: "malonyl-CoA:acyl-carrier-protein S-malonyltransferase activity" EXACT [EC:2.3.1.39] synonym: "MAT" RELATED [EC:2.3.1.39] synonym: "MCAT activity" EXACT [EC:2.3.1.39] xref: EC:2.3.1.39 xref: GO:0004314 xref: MetaCyc:MALONYL-COA-ACP-TRANSACYL-RXN xref: Reactome:10341 is_a: CCO:F0000733 ! fatty-acid synthase activity is_a: CCO:F0003142 ! S-malonyltransferase activity [Term] id: CCO:F0008253 name: [pyruvate dehydrogenase (lipoamide)] phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate." [EC:3.1.3.43] synonym: "[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity" EXACT [] synonym: "phosphopyruvate dehydrogenase phosphatase activity" EXACT [EC:3.1.3.43] synonym: "pyruvate dehydrogenase (lipoamide) phosphatase activity" EXACT [] synonym: "pyruvate dehydrogenase (lipoamide)-phosphatase activity" EXACT [EC:3.1.3.43] synonym: "pyruvate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.43] synonym: "pyruvate dehydrogenase phosphatase activity" EXACT [EC:3.1.3.43] xref: EC:3.1.3.43 xref: GO:0004741 xref: GO:0019906 xref: MetaCyc:3.1.3.43-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0008254 name: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O." [EC:4.2.1.-, GOC:ai] synonym: "(3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity" EXACT [] synonym: "(3R)-hydroxymyristoyl-ACP dehydratase activity" EXACT [] xref: EC:4.2.1.- xref: GO:0008659 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008255 name: (2,3-dihydroxybenzoyl)adenylate synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate = diphosphate + (2,3-dihydroxybenzoyl)adenylate." [EC:2.7.7.58, MetaCyc:2.7.7.58-RXN] subset: gosubset_prok synonym: "2,3-dihydroxybenzoate-AMP ligase activity" EXACT [] synonym: "ATP:2,3-dihydroxybenzoate adenylyltransferase activity" EXACT [EC:2.7.7.58] xref: EC:2.7.7.58 xref: GO:0008668 xref: MetaCyc:DHBAMPLIG-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0008256 name: [acyl-carrier-protein] phosphodiesterase activity namespace: molecular_function def: "Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein." [EC:3.1.4.14] subset: gosubset_prok synonym: "[acyl-carrier protein] phosphodiesterase activity" EXACT [] synonym: "[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase activity" EXACT [EC:3.1.4.14] synonym: "ACP hydrolyase activity" EXACT [EC:3.1.4.14] synonym: "ACP phosphodiesterase activity" EXACT [] synonym: "AcpH" RELATED [EC:3.1.4.14] synonym: "acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity" EXACT [EC:3.1.4.14] synonym: "acyl-carrier-protein phosphodiesterase activity" EXACT [EC:3.1.4.14] synonym: "holo-acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity" EXACT [EC:3.1.4.14] xref: EC:3.1.4.14 xref: GO:0008770 xref: MetaCyc:3.1.4.14-RXN is_a: CCO:F0001701 ! phosphoric diester hydrolase activity [Term] id: CCO:F0008257 name: [citrate (pro-3S)-lyase] ligase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form)." [EC:6.2.1.22] subset: gosubset_prok synonym: "acetate: SH-acyl-carrier-protein enzyme ligase (AMP)" EXACT [EC:6.2.1.22] synonym: "acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming)" BROAD [EC:6.2.1.22] synonym: "acetate:HS-citrate lyase ligase activity" EXACT [EC:6.2.1.22] synonym: "citrate (pro-3S)-lyase ligase activity" EXACT [EC:6.2.1.22] synonym: "citrate lyase ligase activity" EXACT [EC:6.2.1.22] synonym: "citrate lyase synthetase activity" EXACT [EC:6.2.1.22] xref: EC:6.2.1.22 xref: GO:0008771 xref: MetaCyc:CITC-RXN is_a: CCO:F0003437 ! acid-thiol ligase activity [Term] id: CCO:F0008258 name: [isocitrate dehydrogenase (NADP+)] kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate." [EC:2.7.11.5] subset: gosubset_prok synonym: "ATP:isocitrate dehydrogenase (NADP+) phosphotransferase activity" EXACT [EC:2.7.11.5] synonym: "ICDH kinase/phosphatase activity" EXACT [EC:2.7.11.5] synonym: "IDH kinase activity" EXACT [EC:2.7.11.5] synonym: "IDH kinase/phosphatase activity" EXACT [EC:2.7.11.5] synonym: "IDH-K/P" RELATED [EC:2.7.11.5] synonym: "IDHK/P" RELATED [EC:2.7.11.5] synonym: "isocitrate dehydrogenase (NADP) kinase activity" EXACT [EC:2.7.11.5] synonym: "isocitrate dehydrogenase (NADP+) kinase activity" EXACT [EC:2.7.11.5] synonym: "isocitrate dehydrogenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.5] synonym: "isocitrate dehydrogenase kinase activity" EXACT [EC:2.7.11.5] synonym: "isocitrate dehydrogenase kinase/phosphatase activity" EXACT [EC:2.7.11.5] synonym: "STK3" RELATED [EC:2.7.11.5] xref: EC:2.7.11.5 xref: GO:0008772 xref: MetaCyc:PHOSICITDEHASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0008259 name: [protein-PII] uridylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII)." [EC:2.7.7.59] subset: gosubset_prok synonym: "PII uridylyl-transferase activity" EXACT [EC:2.7.7.59] synonym: "protein-PII uridylyltransferase activity" EXACT [EC:2.7.7.59] synonym: "uridyl removing enzyme" RELATED [EC:2.7.7.59] synonym: "uridylyl removing enzyme activity" BROAD [EC:2.7.7.59] synonym: "UTP:[protein-PII] uridylyltransferase activity" EXACT [] synonym: "UTP:protein-PII uridylyltransferase activity" EXACT [EC:2.7.7.59] xref: EC:2.7.7.59 xref: GO:0008773 xref: MetaCyc:URITRANS-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0008260 name: [glutamate-ammonia-ligase] adenylyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + (L-glutamate:ammonia ligase (ADP-forming)) = diphosphate + adenylyl-(L-glutamate:ammonia ligase (ADP-forming))." [EC:2.7.7.42] subset: gosubset_prok synonym: "adenosine triphosphate:glutamine synthetase adenylyltransferase activity" EXACT [EC:2.7.7.42] synonym: "ATP:[glutamate-ammonia-ligase] adenylyltransferase activity" EXACT [] synonym: "ATP:glutamine synthetase adenylyltransferase activity" EXACT [EC:2.7.7.42] synonym: "ATP:L-glutamate:ammonia ligase (ADP-forming) adenylyltransferase activity" EXACT [EC:2.7.7.42] synonym: "glutamate-ammonia-ligase adenylyltransferase activity" EXACT [] synonym: "glutamine-synthetase adenylyltransferase activity" EXACT [EC:2.7.7.42] xref: EC:2.7.7.42 xref: GO:0008882 xref: MetaCyc:GSADENYLATION-RXN is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0008261 name: (+)-abscisic acid 8'-hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-abscisate + NADPH + H+ + O2 = 8'-hydroxyabscisate + NADP+ + H2O." [EC:1.14.13.93] synonym: "(+)-ABA 8'-hydroxylase activity" EXACT [EC:1.14.13.93] synonym: "ABA 8'-hydroxylase activity" EXACT [EC:1.14.13.93] synonym: "ABA 8'-Hydroxylase activity, Abscisate 8'-hydroxylase activity" RELATED [] synonym: "abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)" EXACT [EC:1.14.13.93] synonym: "abscisic acid 8'-hydroxylase activity" EXACT [] xref: EC:1.14.13.93 xref: GO:0010295 xref: MetaCyc:1.14.13.93-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008262 name: [heparan sulfate]-glucosamine N-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-desulfoheparin = adenosine 3',5'-bisphosphate + heparin." [EC:2.8.2.8] comment: Note that this activity includes EC:2.8.2.12 (deleted from EC). synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "[heparan sulphate]-glucosamine N-sulphotransferase activity" EXACT [] synonym: "desulfoheparin sulfotransferase activity" EXACT [] synonym: "glucosaminyl N-deacetylase/N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "heparan sulfate 2-N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "heparan sulfate N-deacetylase/N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "heparan sulfate N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "heparin N-deacetylase/N-sulfotransferase activity" RELATED [] synonym: "heparin N-deacetylase/N-sulphotransferase activity" RELATED [] synonym: "heparin N-sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "heparin-glucosamine N-sulfotransferase activity" EXACT [] synonym: "N-desulfoheparin sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "N-heparan sulfate sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "N-HSST activity" EXACT [EC:2.8.2.8] synonym: "PAPS:DSH sulfotransferase activity" EXACT [EC:2.8.2.8] synonym: "PAPS:N-desulfoheparin sulfotransferase activity" EXACT [EC:2.8.2.8] xref: EC:2.8.2.8 xref: GO:0004393 xref: GO:0015016 xref: GO:0015022 xref: MetaCyc:DESULFOHEPARIN-SULFOTRANSFERASE-RXN is_a: CCO:F0008398 ! heparan sulfate sulfotransferase activity [Term] id: CCO:F0008263 name: [cytochrome c]-arginine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine." [EC:2.1.1.124, GOC:ma] synonym: "cytochrome c-arginine N-methyltransferase activity" EXACT [EC:2.1.1.124] synonym: "S-adenosyl-L-methionine:cytochrome c-arginine nomega-methyltransferasea" RELATED [EC:2.1.1.124] synonym: "S-adenosyl-L-methionine:cytochrome c-arginine omega-N-methyltransferasea" RELATED [EC:2.1.1.124] xref: EC:2.1.1.124 xref: GO:0016275 xref: MetaCyc:2.1.1.124-RXN is_a: CCO:F0003096 ! protein-arginine N-methyltransferase activity [Term] id: CCO:F0008264 name: [myelin basic protein]-arginine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine." [EC:2.1.1.126] synonym: "myelin basic protein methylase activity" EXACT [EC:2.1.1.126] synonym: "myelin basic protein methylase I" RELATED [EC:2.1.1.126] synonym: "myelin basic protein-arginine N-methyltransferase activity" EXACT [EC:2.1.1.126] synonym: "protein methylase I activity" BROAD [EC:2.1.1.126] synonym: "S-adenosyl-L-methionine:myelin-basic-protein-arginine nomega-methyltransferase activity" EXACT [EC:2.1.1.126] synonym: "S-adenosyl-L-methionine:myelin-basic-protein-arginine omega-N-methyltransferase activity" EXACT [EC:2.1.1.126] xref: EC:2.1.1.126 xref: GO:0016277 xref: MetaCyc:2.1.1.126-RXN is_a: CCO:F0003096 ! protein-arginine N-methyltransferase activity [Term] id: CCO:F0008265 name: (R)-6-hydroxynicotine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O2." [EC:1.5.3.6] subset: gosubset_prok synonym: "(R)-6-hydroxynicotine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.6] synonym: "6-hydroxy-D-nicotine oxidase activity" EXACT [] synonym: "D-6-hydroxynicotine oxidase activity" EXACT [EC:1.5.3.6] xref: EC:1.5.3.6 xref: GO:0018530 xref: MetaCyc:(R)-6-HYDROXYNICOTINE-OXIDASE-RXN xref: UM-BBD_enzymeID:e0338 is_a: CCO:F0004062 ! hydroxy-nicotine oxidase activity [Term] id: CCO:F0008266 name: (S)-6-hydroxynicotine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O2." [EC:1.5.3.5] subset: gosubset_prok synonym: "(S)-6-hydroxynicotine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.5] synonym: "6-hydroxy-L-nicotine oxidase activity" EXACT [] synonym: "6-hydroxy-L-nicotine:oxygen oxidoreductase activity" EXACT [EC:1.5.3.5] synonym: "L-6-hydroxynicotine oxidase activity" EXACT [] xref: EC:1.5.3.5 xref: GO:0018531 xref: MetaCyc:(S)-6-HYDROXYNICOTINE-OXIDASE-RXN xref: UM-BBD_enzymeID:e0339 is_a: CCO:F0004062 ! hydroxy-nicotine oxidase activity [Term] id: CCO:F0008267 name: (S)-limonene 3-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-isopiperitenol + NADP+ + H2O." [EC:1.14.13.47] synonym: "(-)-limonene 3-hydroxylase activity" EXACT [EC:1.14.13.47] synonym: "(-)-limonene 3-monooxygenase activity" EXACT [] synonym: "(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) activity" EXACT [EC:1.14.13.47] synonym: "(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.47] synonym: "limonene 3-hydroxylase activity" EXACT [] xref: EC:1.14.13.47 xref: GO:0018674 xref: MetaCyc:(-)-LIMONENE-3-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0467 is_a: CCO:F0004059 ! limonene monooxygenase activity [Term] id: CCO:F0008268 name: (S)-limonene 6-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O." [EC:1.14.13.48] synonym: "(-)-limonene 6-hydroxylase activity" EXACT [EC:1.14.13.48] synonym: "(-)-limonene 6-monooxygenase activity" EXACT [] synonym: "(-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity" EXACT [EC:1.14.13.48] synonym: "(S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating)" EXACT [EC:1.14.13.48] synonym: "limonene 6-hydroxylase activity" EXACT [] xref: EC:1.14.13.48 xref: GO:0018675 xref: MetaCyc:(-)-LIMONENE-6-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0445 is_a: CCO:F0004059 ! limonene monooxygenase activity [Term] id: CCO:F0008269 name: (S)-limonene 7-monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-perillyl alcohol + NADP+ + H2O." [EC:1.14.13.49] synonym: "(-)-limonene 7-monooxygenase activity" EXACT [] synonym: "(-)-limonene hydroxylase activity" EXACT [EC:1.14.13.49] synonym: "(-)-limonene monooxygenase activity" EXACT [EC:1.14.13.49] synonym: "(-)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating) activity" EXACT [EC:1.14.13.49] synonym: "(S)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating)" EXACT [EC:1.14.13.49] synonym: "limonene hydroxylase activity" EXACT [] xref: EC:1.14.13.49 xref: GO:0018676 xref: MetaCyc:(-)-LIMONENE-7-MONOOXYGENASE-RXN xref: UM-BBD_enzymeID:e0458 is_a: CCO:F0004059 ! limonene monooxygenase activity [Term] id: CCO:F0008270 name: (3,5-dichlorophenylurea)acetate amidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine." [UM-BBD_enzymeID:e0440] xref: EC:3.5.1.- xref: GO:0018749 xref: UM-BBD_enzymeID:e0440 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0008271 name: (S)-2-haloacid dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide." [EC:3.8.1.2] subset: gosubset_prok synonym: "(S)-2-haloacid halidohydrolase activity" EXACT [EC:3.8.1.2] synonym: "2-haloacid dehalogenase activity" EXACT [] synonym: "2-haloacid halidohydrolase activity" EXACT [EC:3.8.1.2] synonym: "2-haloalkanoic acid dehalogenase activity" EXACT [EC:3.8.1.2] synonym: "2-haloalkanoid acid halidohydrolase activity" EXACT [EC:3.8.1.2] synonym: "2-halocarboxylic acid dehalogenase II activity" EXACT [EC:3.8.1.2] synonym: "DL-2-haloacid dehalogenase activity" EXACT [EC:3.8.1.2] synonym: "halocarboxylic acid halidohydrolase activity" EXACT [EC:3.8.1.2] synonym: "L-2-haloacid dehalogenase activity" EXACT [EC:3.8.1.2] synonym: "L-DEX activity" EXACT [EC:3.8.1.2] xref: EC:3.8.1.2 xref: GO:0018784 xref: MetaCyc:2-HALOACID-DEHALOGENASE-RXN xref: UM-BBD_enzymeID:e0021 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0008272 name: (hydroxyamino)benzene mutase activity namespace: molecular_function def: "Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol." [EC:5.4.4.1, UM-BBD_enzymeID:e0246] synonym: "(hydroxyamino)benzene hydroxymutase activity" EXACT [EC:5.4.4.1] synonym: "HAB mutase activity" EXACT [EC:5.4.4.1] synonym: "hydroxylaminobenzene hydroxymutase activity" EXACT [EC:5.4.4.1] synonym: "hydroxylaminobenzene mutase activity" EXACT [EC:5.4.4.1] xref: GO:0018824 xref: UM-BBD_enzymeID:e0246 is_a: CCO:F0007827 ! intramolecular transferase activity, transferring hydroxy groups [Term] id: CCO:F0008273 name: (R)-aminopropanol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + NADH + H+." [EC:1.1.1.75] synonym: "(R)-1-aminopropan-2-ol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.75] synonym: "1-aminopropan-2-ol-dehydrogenase activity" EXACT [EC:1.1.1.75] synonym: "1-aminopropan-2-ol-NAD+ dehydrogenase activity" EXACT [EC:1.1.1.75] synonym: "DL-1-aminopropan-2-ol: NAD+ dehydrogenase activity" EXACT [EC:1.1.1.75] synonym: "L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase activity" EXACT [EC:1.1.1.75] synonym: "L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.75] synonym: "L-aminopropanol dehydrogenase activity" EXACT [] xref: EC:1.1.1.75 xref: GO:0019147 xref: MetaCyc:AMINOPROPDEHYDROG-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008274 name: [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity namespace: molecular_function def: "Modification of the activity of the enzyme [pyruvate dehydrogenase (lipoamide)] phosphatase." [EC:3.1.3.43, GOC:ai] synonym: "[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity" NARROW [] xref: GO:0019909 is_a: CCO:F0004205 ! protein phosphatase regulator activity [Term] id: CCO:F0008275 name: [methionine synthase] reductase activity namespace: molecular_function def: "Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+." [EC:1.16.1.8] comment: Note that this was EC:2.1.1.135. synonym: "5-methyltetrahydrofolate-homocysteine methyltransferase reductase" RELATED [] synonym: "[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity" EXACT [] synonym: "methionine synthase cob(II)alamin reductase (methylating) activity" EXACT [EC:1.16.1.8] synonym: "methionine synthase reductase activity" EXACT [EC:1.16.1.8] synonym: "methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)" EXACT [EC:1.16.1.8] synonym: "methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity" EXACT [EC:1.16.1.8] xref: EC:1.16.1.8 xref: GO:0030586 xref: MetaCyc:2.1.1.135-RXN is_a: CCO:F0003305 ! oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor [Term] id: CCO:F0008276 name: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline." [EC:2.1.1.115] synonym: "(RS)-tetrahydrobenzylisoquinoline N-methyltransferase activity" EXACT [EC:2.1.1.115] synonym: "(rs)-tetrahydrobenzylisoquinoline N-methyltransferase activity" EXACT [EC:2.1.1.115] synonym: "norreticuline N-methyltransferase activity" EXACT [EC:2.1.1.115] synonym: "S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity" EXACT [EC:2.1.1.115] xref: EC:2.1.1.115 xref: GO:0030776 xref: MetaCyc:2.1.1.115-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008277 name: (S)-scoulerine 9-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (S)-scoulerine = S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine." [EC:2.1.1.117] synonym: "S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase activity" EXACT [EC:2.1.1.117] synonym: "S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase activity" EXACT [EC:2.1.1.117] xref: EC:2.1.1.117 xref: GO:0030777 xref: MetaCyc:2.1.1.117-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008278 name: (S)-tetrahydroprotoberberine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine." [EC:2.1.1.122] synonym: "S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase activity" EXACT [EC:2.1.1.122] synonym: "tetrahydroprotoberberine cis-N-methyltransferase activity" EXACT [EC:2.1.1.122] xref: EC:2.1.1.122 xref: GO:0030782 xref: MetaCyc:2.1.1.122-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008279 name: [cytochrome c]-methionine S-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine." [EC:2.1.1.123] synonym: "cytochrome c-methionine S-methyltransferase activity" EXACT [EC:2.1.1.123] synonym: "S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity" EXACT [EC:2.1.1.123] xref: EC:2.1.1.123 xref: GO:0030783 xref: MetaCyc:2.1.1.123-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008280 name: [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine." [EC:2.1.1.127] synonym: "ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity" EXACT [EC:2.1.1.127] synonym: "ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity" EXACT [EC:2.1.1.127] synonym: "ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity" EXACT [EC:2.1.1.127] synonym: "RuBisCO LSMT activity" EXACT [EC:2.1.1.127] synonym: "rubisco methyltransferase activity" EXACT [EC:2.1.1.127] synonym: "RuBisCO methyltransferase activity" EXACT [EC:2.1.1.127] synonym: "S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity" EXACT [EC:2.1.1.127] synonym: "S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity" EXACT [EC:2.1.1.127] xref: EC:2.1.1.127 xref: GO:0030785 xref: MetaCyc:2.1.1.127-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008281 name: (RS)-norcoclaurine 6-O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine." [EC:2.1.1.128] synonym: "S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase activity" EXACT [EC:2.1.1.128] xref: EC:2.1.1.128 xref: GO:0030786 xref: MetaCyc:2.1.1.128-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008282 name: (S)-coclaurine-N-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine." [EC:2.1.1.140] synonym: "S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase activity" EXACT [EC:2.1.1.140] xref: EC:2.1.1.140 xref: GO:0030794 xref: MetaCyc:2.1.1.140-RXN is_a: CCO:F0002103 ! S-adenosylmethionine-dependent methyltransferase activity [Term] id: CCO:F0008283 name: (+)-trans-carveol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-trans-carveol + NAD+ = (+)-(S)-carvone + NADH + H+." [EC:1.1.1.275] synonym: "(+)-trans-carveol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.275] xref: EC:1.1.1.275 xref: GO:0033702 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008284 name: (S)-mandelate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor." [EC:1.1.99.31] synonym: "(S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity" EXACT [EC:1.1.99.31] synonym: "L(+)-mandelate dehydrogenase activity" EXACT [EC:1.1.99.31] synonym: "MDH" RELATED [EC:1.1.99.31] xref: EC:1.1.99.31 xref: GO:0033720 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0008285 name: (R)-benzylsuccinyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein." [EC:1.3.99.21] synonym: "(R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity" EXACT [EC:1.3.99.21] synonym: "(R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity" EXACT [EC:1.3.99.21] synonym: "BbsG" RELATED [EC:1.3.99.21] xref: EC:1.3.99.21 xref: GO:0033734 xref: UM-BBD_enzymeID:e0650 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0008286 name: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S." [EC:2.8.2.29] synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity" BROAD [EC:2.8.2.29] synonym: "3-OST-2" RELATED [EC:2.8.2.29] synonym: "glucosaminyl 3-O-sulfotransferase 2 activity" EXACT [EC:2.8.2.29] synonym: "glucosaminyl 3-O-sulfotransferase activity" BROAD [EC:2.8.2.29] synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 activity" EXACT [EC:2.8.2.29] synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" BROAD [EC:2.8.2.29] synonym: "heparin-glucosamine 3-sulfotransferase 2 activity" RELATED [] synonym: "isoform/isozyme 2 (3-OST-2, HS3ST2)" RELATED [EC:2.8.2.29] xref: EC:2.8.2.29 xref: GO:0033871 is_a: CCO:F0008398 ! heparan sulfate sulfotransferase activity [Term] id: CCO:F0008287 name: [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate." [EC:2.8.2.30] synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity" BROAD [EC:2.8.2.30] synonym: "3-OST-3" RELATED [EC:2.8.2.30] synonym: "glucosaminyl 3-O-sulfotransferase 3 activity" EXACT [EC:2.8.2.30] synonym: "glucosaminyl 3-O-sulfotransferase 3a, 3b activity" EXACT [EC:2.8.2.30] synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3 activity" EXACT [EC:2.8.2.30] synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A activity" EXACT [EC:2.8.2.30] synonym: "heparin-glucosamine 3-sulfotransferase 3 activity" RELATED [] synonym: "isoform/isozyme 3a and 3b (3-OST-3A, 3-OST-3B, HS3ST3A, HS3ST3B)" RELATED [EC:2.8.2.30] xref: EC:2.8.2.30 xref: GO:0033872 is_a: CCO:F0008398 ! heparan sulfate sulfotransferase activity [Term] id: CCO:F0008288 name: (R)-2-haloacid dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide." [EC:3.8.1.9] synonym: "(R)-2-haloacid halidohydrolase activity" EXACT [EC:3.8.1.9] synonym: "2-haloalkanoic acid dehalogenase activity" BROAD [EC:3.8.1.9] synonym: "2-haloalkanoid acid halidohydrolase activity" BROAD [EC:3.8.1.9] synonym: "D-2-haloacid dehalogenase activity" EXACT [EC:3.8.1.9] synonym: "D-DEX" RELATED [EC:3.8.1.9] xref: EC:3.8.1.9 xref: GO:0033975 is_a: CCO:F0004066 ! hydrolase activity, acting on acid halide bonds, in C-halide compounds [Term] id: CCO:F0008289 name: (R)-limonene synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate = (+)-(4R)-limonene + diphosphate." [EC:4.2.3.20] synonym: "(+)-limonene synthase activity" EXACT [EC:4.2.3.20] synonym: "geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming] activity" EXACT [EC:4.2.3.20] synonym: "geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming] activity" EXACT [EC:4.2.3.20] xref: EC:4.2.3.20 xref: GO:0034002 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0008290 name: (carboxyethyl)arginine beta-lactam-synthase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-N2-(2-carboxyethyl)arginine = AMP + diphosphate + deoxyamidinoproclavaminate." [EC:6.3.3.4] synonym: "beta-lactam synthetase activity" EXACT [EC:6.3.3.4] synonym: "L-2-N-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity" EXACT [EC:6.3.3.4] synonym: "L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity" EXACT [EC:6.3.3.4] xref: EC:6.3.3.4 xref: GO:0034027 is_a: CCO:F0003441 ! cyclo-ligase activity [Term] id: CCO:F0008291 name: [formate-C-acetyltransferase]-activating enzyme activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical." [EC:1.97.1.4, GOC:jl] synonym: "[pyruvate formate-lyase]-activating enzyme activity" EXACT [EC:1.97.1.4] synonym: "formate acetyltransferase activating enzyme activity" EXACT [EC:1.97.1.4] synonym: "formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity" EXACT [EC:1.97.1.4] synonym: "formate C-acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)" EXACT [EC:1.97.1.4] synonym: "formate-C-acetyltransferase-activating enzyme" RELATED [EC:1.97.1.4] synonym: "PFL activase activity" EXACT [EC:1.97.1.4] synonym: "PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving) activity" EXACT [EC:1.97.1.4] synonym: "pyruvate formate-lyase-activating enzyme" RELATED [EC:1.97.1.4] xref: EC:1.97.1.4 xref: GO:0008862 xref: GO:0043365 xref: MetaCyc:TDCEACT-RXN is_a: CCO:F0003172 ! oxidoreductase activity is_a: CCO:F0005842 ! catalysis of free radical formation [Term] id: CCO:F0008292 name: (R)-2-hydroxyisocaproate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+." [GOC:jl, PMID:16957230] subset: gosubset_prok xref: EC:1.1.1.- xref: GO:0043713 is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008293 name: (R)-citramalate synthase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA." [GOC:jl, PMID:9864346] subset: gosubset_prok synonym: "citramalate synthase" BROAD [] xref: EC:2.3.3.- xref: GO:0043714 is_a: CCO:F0006267 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer [Term] id: CCO:F0008294 name: (S)-lactate 2-kinase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP." [IMG:00356, PMID:11535063] subset: gosubset_prok synonym: "lactate 2-kinase activity" EXACT [] xref: EC:2.7.1.- xref: GO:0043841 xref: MetaCyc:RXN-8076 is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0008295 name: (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity namespace: molecular_function def: "Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate." [PMID:15356000, PMID:16494480] comment: This function is involved in archaeal lipid synthesis. subset: gosubset_prok synonym: "2,3-dGGGPS" EXACT [] synonym: "DGGGP synthase activity" EXACT [] synonym: "DGGGPS" EXACT [] synonym: "UbiA" RELATED [] xref: EC:2.5.1.- xref: GO:0043888 is_a: CCO:F0000268 ! polyprenyltransferase activity is_a: CCO:F0000756 ! geranyltranstransferase activity [Term] id: CCO:F0008296 name: (S)-3-O-geranylgeranylglyceryl phosphate activity namespace: molecular_function def: "Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate." [PMID:12801917, PMID:17253090, PMID:8408023] comment: This function is involved in archaeal lipid synthesis. subset: gosubset_prok synonym: "(S)-3-O-geranylgeranylglycerylphosphate activity" EXACT [] synonym: "(S)-GGGP synthase activity" EXACT [] synonym: "GGGP synthase activity" EXACT [] synonym: "GGGPS" EXACT [] xref: GO:0043889 is_a: CCO:F0001032 ! prenyltransferase activity [Term] id: CCO:F0008297 name: (S)-usnate reductase activity namespace: molecular_function def: "Catalysis of the reaction: L-usnic acid + NADH + H+ = NAD+ + 2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methyl-phenyl)-3-hydroxy-6-methyl-cyclohexa-2,4-dienone." [EC:1.1.1.199, MetaCyc:1.1.1.199-RXN] synonym: "L-usnic acid dehydrogenase activity" EXACT [EC:1.1.1.199] synonym: "reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming)" EXACT [EC:1.1.1.199] xref: EC:1.1.1.199 xref: GO:0046998 xref: MetaCyc:1.1.1.199-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008298 name: (R)-4-hydroxyphenyllactate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + H+ + 3-(4-hydroxyphenyl)pyruvate." [EC:1.1.1.222, MetaCyc:1.1.1.222-RXN] synonym: "(R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase activity" EXACT [EC:1.1.1.222] synonym: "(R)-aromatic lactate dehydrogenase activity" EXACT [EC:1.1.1.222] synonym: "D-hydrogenase, D-aryllactate" EXACT [EC:1.1.1.222] xref: EC:1.1.1.222 xref: GO:0047029 xref: MetaCyc:1.1.1.222-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008299 name: (S)-carnitine 3-dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + L-carnitine = NADH + H+ + 3-dehydrocarnitine." [EC:1.1.1.254, MetaCyc:1.1.1.254-RXN] synonym: "(S)-carnitine:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.254] synonym: "D-carnitine dehydrogenase activity" EXACT [EC:1.1.1.254] xref: EC:1.1.1.254 xref: GO:0047041 xref: MetaCyc:1.1.1.254-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008300 name: (R)-2-hydroxy-fatty-acid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + R-2-hydroxystearate = NADH + H+ + 2-oxostearate." [EC:1.1.1.98, MetaCyc:1.1.1.98-RXN] synonym: "(R)-2-hydroxystearate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.98] synonym: "2-hydroxy fatty acid oxidase" BROAD [EC:1.1.1.98] synonym: "D-2-hydroxy fatty acid dehydrogenase activity" EXACT [EC:1.1.1.98] xref: EC:1.1.1.98 xref: GO:0047049 xref: MetaCyc:1.1.1.98-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008301 name: (S)-2-hydroxy-fatty-acid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + (S)-2-hydroxystearate = NADH + H+ + 2-oxostearate." [EC:1.1.1.99, MetaCyc:1.1.1.99-RXN] synonym: "(S)-2-hydroxystearate:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.99] synonym: "2-hydroxy fatty acid oxidase" BROAD [EC:1.1.1.99] synonym: "dehydrogenase, L-2-hydroxy fatty acid" EXACT [EC:1.1.1.99] synonym: "L-2-hydroxy fatty acid dehydrogenase activity" EXACT [EC:1.1.1.99] xref: EC:1.1.1.99 xref: GO:0047050 xref: MetaCyc:1.1.1.99-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008302 name: (S)-stylopine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + S-cheilanthifoline = 2 H2O + NADP+ + S-stylopine." [EC:1.14.21.1, MetaCyc:1.1.3.32-RXN] synonym: "(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming) activity" EXACT [EC:1.14.21.1] synonym: "(S)-cheilanthifoline,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)" EXACT [EC:1.14.21.1] xref: EC:1.14.21.1 xref: GO:0047052 xref: MetaCyc:1.1.3.32-RXN is_a: CCO:F0006310 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated [Term] id: CCO:F0008303 name: (S)-cheilanthifoline synthase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + S-scoulerine = 2 H2O + NADP+ + S-cheilanthifoline." [EC:1.14.21.2, MetaCyc:1.14.21.2-RXN] synonym: "(S)-scoulerine oxidase (methylenedioxy-bridge-forming) activity" EXACT [] synonym: "(S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)" EXACT [EC:1.14.21.2] xref: EC:1.14.21.2 xref: GO:0047053 xref: MetaCyc:1.14.21.2-RXN is_a: CCO:F0006310 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated [Term] id: CCO:F0008304 name: (S)-canadine synthase activity namespace: molecular_function def: "Catalysis of the reaction: O2 + NADPH + H+ + S-tetrahydrocolumbamine = 2 H2O + NADP+ + S-canadine." [EC:1.14.21.5, MetaCyc:1.1.3.36-RXN] synonym: "(S)-tetrahydroberberine synthase activity" EXACT [EC:1.14.21.5] synonym: "(S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming) activity" EXACT [EC:1.14.21.5] synonym: "(S)-tetrahydrocolumbamine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)" EXACT [EC:1.14.21.5] xref: EC:1.14.21.5 xref: GO:0047056 xref: MetaCyc:1.1.3.36-RXN is_a: CCO:F0006310 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated [Term] id: CCO:F0008305 name: (R)-pantolactone dehydrogenase (flavin) activity namespace: molecular_function def: "Catalysis of the reaction: acceptor + pantoyl lactone = reduced acceptor + 2-dehydropantoyl lactone." [EC:1.1.99.27, MetaCyc:1.1.99.27-RXN] synonym: "(R)-pantolactone:acceptor oxidoreductase (flavin-containing)" EXACT [EC:1.1.99.27] synonym: "(R)-pantoyllactone dehydrogenase (flavin) activity" EXACT [EC:1.1.99.27] synonym: "2-dehydropantolactone reductase (flavin) activity" EXACT [EC:1.1.99.27] synonym: "2-dehydropantoyl-lactone reductase (flavin) activity" EXACT [EC:1.1.99.27] xref: EC:1.1.99.27 xref: GO:0047060 xref: MetaCyc:1.1.99.27-RXN is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0008306 name: (R)-3-hydroxyacid-ester dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + ethyl (R)-3-hydroxyhexanoate = NADPH + ethyl-3-oxohexanoate." [EC:1.1.1.279, MetaCyc:1.2.1.55-RXN] comment: Note that this term was EC:1.2.1.55. synonym: "(R)-3-hydroxyacid ester dehydrogenase activity" EXACT [] synonym: "3-oxo ester (R)-reductase activity" EXACT [EC:1.1.1.279] synonym: "ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.279] xref: EC:1.1.1.279 xref: GO:0047108 xref: MetaCyc:1.2.1.55-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008307 name: (S)-3-hydroxyacid-ester dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NADP+ + ethyl (S)-3-hydroxyhexanoate = NADPH + ethyl-3-oxohexanoate." [EC:1.1.1.280, MetaCyc:1.2.1.56-RXN] comment: Note that this term was EC:1.2.1.56. synonym: "(S)-3-hydroxyacid ester dehydrogenase activity" EXACT [] synonym: "3-oxo ester (S)-reductase activity" EXACT [EC:1.1.1.280] synonym: "ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity" EXACT [EC:1.1.1.280] xref: EC:1.1.1.280 xref: GO:0047109 xref: MetaCyc:1.2.1.56-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008308 name: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: NAD+ + (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate = NADH + CO2 + protocatechuate." [EC:1.3.1.53, MetaCyc:1.3.1.53-RXN] synonym: "(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity" EXACT [EC:1.3.1.53] synonym: "(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase activity" EXACT [EC:1.3.1.53] synonym: "dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity" EXACT [EC:1.3.1.53] xref: EC:1.3.1.53 xref: GO:0047120 xref: MetaCyc:1.3.1.53-RXN is_a: CCO:F0003229 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008309 name: (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-(alpha-N-acetylneuraminyl-2,6)-N-acetyl-D-galactosaminyl-R + CMP." [EC:2.4.99.7, MetaCyc:2.4.99.7-RXN] synonym: "(alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] synonym: "(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity" EXACT [] synonym: "alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] synonym: "CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyl-transferase activity" EXACT [EC:2.4.99.7] synonym: "cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] synonym: "NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] synonym: "neuac-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] synonym: "sialyltransferase 3C activity" RELATED [EC:2.4.99.7] synonym: "sialyltransferase 7D activity" RELATED [EC:2.4.99.7] synonym: "SIAT7" RELATED [EC:2.4.99.7] synonym: "ST6GALNAC activity" EXACT [EC:2.4.99.7] xref: EC:2.4.99.7 xref: GO:0047290 xref: MetaCyc:2.4.99.7-RXN is_a: CCO:F0001849 ! sialyltransferase activity [Term] id: CCO:F0008310 name: (S)-3-amino-2-methylpropionate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + (S)-3-amino-2-methylpropanoate = L-glutamate + methylmalonate-semialdehyde." [EC:2.6.1.22, MetaCyc:2.6.1.22-RXN] subset: gosubset_prok synonym: "(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.22] synonym: "(S)-3-amino-2-methylpropionate aminotransferase activity" EXACT [] synonym: "beta-aminobutyric transaminase activity" EXACT [EC:2.6.1.22] synonym: "beta-aminoisobutyrate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.22] synonym: "L-3-aminoisobutyrate aminotransferase activity" EXACT [EC:2.6.1.22] synonym: "L-3-aminoisobutyrate transaminase activity" EXACT [EC:2.6.1.22] synonym: "L-3-aminoisobutyric aminotransferase activity" EXACT [EC:2.6.1.22] synonym: "L-AIBAT activity" EXACT [EC:2.6.1.22] xref: EC:2.6.1.22 xref: GO:0047298 xref: MetaCyc:2.6.1.22-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0008311 name: (R)-3-amino-2-methylpropionate-pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + (R)-3-amino-2-methylpropanoate = L-alanine + methylmalonate-semialdehyde." [EC:2.6.1.40, MetaCyc:2.6.1.40-RXN] comment: Note that this function was EC:2.6.1.61. synonym: "(R)-3-amino-2-methylpropanoate aminotransferase activity" EXACT [] synonym: "(R)-3-amino-2-methylpropanoate transaminase activity" EXACT [] synonym: "(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] synonym: "(R)-3-amino-2-methylpropionate transaminase activity" EXACT [] synonym: "(R)-3-amino-2-methylpropionate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] synonym: "(R)-3-amino-2-methylpropionate-pyruvate aminotransferase activity" EXACT [] synonym: "beta-aminoisobutyrate--pyruvate transaminase activity" EXACT [EC:2.6.1.40] synonym: "beta-aminoisobutyrate-pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] synonym: "D-3-aminoisobutyrate--pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] synonym: "D-3-aminoisobutyrate--pyruvate transaminase activity" EXACT [EC:2.6.1.40] synonym: "D-3-aminoisobutyrate-pyruvate transaminase activity" EXACT [EC:2.6.1.40] synonym: "D-AIBAT activity" EXACT [EC:2.6.1.40] synonym: "D-beta-aminoisobutyrate:pyruvate aminotransferase activity" EXACT [EC:2.6.1.40] xref: EC:2.6.1.40 xref: GO:0047305 xref: GO:0047314 xref: MetaCyc:2.6.1.40-RXN is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0008312 name: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity namespace: molecular_function def: "Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP." [EC:2.7.11.31, MetaCyc:2.7.1.109-RXN] synonym: "3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity" EXACT [EC:2.7.11.31] synonym: "3-hydroxy-3-methylglutaryl-CoA reductase kinase activity" EXACT [EC:2.7.11.31] synonym: "AMPK" RELATED [EC:2.7.11.31] synonym: "ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity" EXACT [EC:2.7.11.31] synonym: "beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity" EXACT [EC:2.7.11.31] synonym: "HMG-CoA reductase kinase activity" EXACT [EC:2.7.11.31] synonym: "hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity" EXACT [EC:2.7.11.31] synonym: "hydroxymethylglutaryl coenzyme A reductase kinase activity" EXACT [EC:2.7.11.31] synonym: "hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity" EXACT [EC:2.7.11.31] synonym: "hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity" EXACT [EC:2.7.11.31] synonym: "hydroxymethylglutaryl-CoA reductase kinase activity" EXACT [EC:2.7.11.31] synonym: "reductase kinase activity" BROAD [EC:2.7.11.31] synonym: "STK29" RELATED [EC:2.7.11.31] xref: EC:2.7.11.31 xref: GO:0047322 xref: MetaCyc:2.7.1.109-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0008313 name: [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate." [EC:2.7.11.4] synonym: "3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity" EXACT [EC:2.7.11.4] synonym: "[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity" EXACT [] synonym: "ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity" EXACT [EC:2.7.11.4] synonym: "BCK" RELATED [EC:2.7.11.4] synonym: "BCKD kinase activity" EXACT [EC:2.7.11.4] synonym: "BCODH kinase activity" EXACT [EC:2.7.11.4] synonym: "branched-chain 2-oxo acid dehydrogenase kinase activity" EXACT [EC:2.7.11.4] synonym: "branched-chain alpha-ketoacid dehydrogenase kinase activity" EXACT [EC:2.7.11.4] synonym: "branched-chain keto acid dehydrogenase kinase activity" EXACT [EC:2.7.11.4] synonym: "branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.4] synonym: "STK2" RELATED [EC:2.7.11.4] xref: EC:2.7.11.4 xref: GO:0047323 xref: MetaCyc:2.7.11.4-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0008314 name: [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)]." [EC:3.1.3.47, MetaCyc:3.1.3.47-RXN] synonym: "hydroxymethylglutaryl-CoA reductase (NADPH)-phosphatase activity" EXACT [EC:3.1.3.47] synonym: "hydroxymethylglutaryl-CoA reductase (NADPH)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.47] synonym: "reductase phosphatase activity" BROAD [EC:3.1.3.47] xref: EC:3.1.3.47 xref: GO:0047384 xref: MetaCyc:3.1.3.47-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0008315 name: [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]." [EC:3.1.3.52, MetaCyc:3.1.3.52-RXN] synonym: "3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphatase activity" EXACT [EC:3.1.3.52] synonym: "3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.52] synonym: "branched-chain 2-keto acid dehydrogenase phosphatase activity" EXACT [EC:3.1.3.52] synonym: "branched-chain alpha-keto acid dehydrogenase phosphatase" BROAD [EC:3.1.3.52] synonym: "branched-chain oxo-acid dehydrogenase phosphatase activity" RELATED [EC:3.1.3.52] xref: EC:3.1.3.52 xref: GO:0047385 xref: MetaCyc:3.1.3.52-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0008316 name: (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity namespace: molecular_function def: "Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = cyclohexanone + acetyl-CoA." [EC:4.1.3.35, MetaCyc:4.1.3.35-RXN] synonym: "(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.35] synonym: "(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase activity" EXACT [EC:4.1.3.35] xref: EC:4.1.3.35 xref: GO:0047446 xref: MetaCyc:4.1.3.35-RXN is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0008317 name: (+)-delta-cadinene synthase activity namespace: molecular_function def: "Catalysis of the reaction: trans,trans-farnesyl diphosphate = pyrophosphate + (+)-delta-cadinene." [EC:4.2.3.13, MetaCyc:4.6.1.11-RXN] synonym: "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)" EXACT [EC:4.2.3.13] synonym: "D-cadinene synthase activity" EXACT [EC:4.2.3.13] xref: EC:4.2.3.13 xref: GO:0047461 xref: MetaCyc:4.6.1.11-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0008318 name: (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(1,4-alpha-D-glucosyl)(n-1)-D-glucose = 1-alpha-D-(1,4-alpha-D-glucosyl)(n-1)-alpha-D-glucopyranoside." [EC:5.4.99.15, MetaCyc:5.4.99.15-RXN] subset: gosubset_prok synonym: "(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase" BROAD [EC:5.4.99.15] synonym: "malto-oligosyltrehalose synthase activity" EXACT [EC:5.4.99.15] synonym: "maltodextrin alpha-D-glucosyltransferase activity" EXACT [EC:5.4.99.15] xref: EC:5.4.99.15 xref: GO:0047470 xref: MetaCyc:5.4.99.15-RXN is_a: CCO:F0003427 ! intramolecular transferase activity [Term] id: CCO:F0008319 name: (+)-borneol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-borneol + NAD+ = (+)-camphor + NADH + H+." [EC:1.1.1.198, MetaCyc:(+)-BORNEOL-DEHYDROGENASE-RXN] synonym: "(+)-borneol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.198] synonym: "bicyclic monoterpenol dehydrogenase activity" EXACT [EC:1.1.1.198] xref: EC:1.1.1.198 xref: GO:0047500 xref: MetaCyc:(+)-BORNEOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008320 name: (+)-neomenthol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-neomenthol + NADP+ = (-)-menthone + NADPH + H+." [EC:1.1.1.208, MetaCyc:(+)-NEOMENTHOL-DEHYDROGENASE-RXN] synonym: "(+)-neomenthol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.208] synonym: "monoterpenoid dehydrogenase activity" BROAD [EC:1.1.1.208] xref: EC:1.1.1.208 xref: GO:0047501 xref: MetaCyc:(+)-NEOMENTHOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008321 name: (+)-sabinol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (+)-cis-sabinol + NAD+ = (+)-sabinone + NADH + H+." [EC:1.1.1.228, MetaCyc:(+)-SABINOL-DEHYDROGENASE-RXN] synonym: "(+)-cis-sabinol dehydrogenase activity" EXACT [EC:1.1.1.228] synonym: "(+)-cis-sabinol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.228] xref: EC:1.1.1.228 xref: GO:0047502 xref: MetaCyc:(+)-SABINOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008322 name: (-)-borneol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-borneol + NAD+ = (-)-camphor + NADH + H+." [EC:1.1.1.227, MetaCyc:(-)-BORNEOL-DEHYDROGENASE-RXN] synonym: "(-)-borneol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.227] xref: EC:1.1.1.227 xref: GO:0047503 xref: MetaCyc:(-)-BORNEOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008323 name: (-)-menthol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-menthol + NADP+ = (-)-menthone + NADPH + H+." [EC:1.1.1.207, MetaCyc:(-)-MENTHOL-DEHYDROGENASE-RXN] synonym: "(-)-menthol:NADP+ oxidoreductase activity" EXACT [EC:1.1.1.207] synonym: "monoterpenoid dehydrogenase activity" BROAD [EC:1.1.1.207] xref: EC:1.1.1.207 xref: GO:0047504 xref: MetaCyc:(-)-MENTHOL-DEHYDROGENASE-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008324 name: (-)-menthol monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: (-)-menthol + NADPH + H+ + O2 = p-menthane-3,8-diol + NADP+ + H2O." [EC:1.14.13.46, MetaCyc:(-)-MENTHOL-MONOOXYGENASE-RXN] synonym: "(-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)" EXACT [EC:1.14.13.46] synonym: "l-menthol monooxygenase activity" EXACT [EC:1.14.13.46] xref: EC:1.14.13.46 xref: GO:0047505 xref: MetaCyc:(-)-MENTHOL-MONOOXYGENASE-RXN is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008325 name: (deoxy)adenylate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + dAMP = ADP + dADP." [EC:2.7.4.11, MetaCyc:(DEOXY)ADENYLATE-KINASE-RXN] synonym: "ATP:(d)AMP phosphotransferase activity" EXACT [EC:2.7.4.11] xref: EC:2.7.4.11 xref: GO:0047506 xref: MetaCyc:(DEOXY)ADENYLATE-KINASE-RXN is_a: CCO:F0003114 ! kinase activity is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor [Term] id: CCO:F0008326 name: (deoxy)nucleoside-phosphate kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate." [EC:2.7.4.13, MetaCyc:(DEOXY)NUCLEOSIDE-PHOSPHATE-KINASE-RXN] synonym: "ATP:deoxynucleoside-phosphate phosphotransferase activity" EXACT [EC:2.7.4.13] synonym: "deoxynucleoside monophosphate kinase activity" EXACT [EC:2.7.4.13] synonym: "deoxynucleoside-5'-monophosphate kinase activity" EXACT [EC:2.7.4.13] synonym: "deoxyribonucleoside monophosphokinase activity" EXACT [EC:2.7.4.13] xref: EC:2.7.4.13 xref: GO:0047507 xref: MetaCyc:(DEOXY)NUCLEOSIDE-PHOSPHATE-KINASE-RXN is_a: CCO:F0003348 ! phosphotransferase activity, phosphate group as acceptor is_a: CCO:F0004128 ! nucleobase, nucleoside, nucleotide kinase activity [Term] id: CCO:F0008327 name: (R)-2-methylmalate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-2-methylmalate = 2-methylmaleate + H2O." [EC:4.2.1.35, MetaCyc:(R)-2-METHYLMALATE-DEHYDRATASE-RXN] synonym: "(-)-citramalate hydro-lyase activity" EXACT [EC:4.2.1.35] synonym: "(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)" EXACT [EC:4.2.1.35] synonym: "(R)-2-methylmalate hydro-lyase activity" EXACT [EC:4.2.1.35] synonym: "citraconase activity" EXACT [EC:4.2.1.35] synonym: "citraconate hydratase activity" EXACT [EC:4.2.1.35] synonym: "citramalate hydro-lyase activity" EXACT [EC:4.2.1.35] xref: EC:4.2.1.35 xref: GO:0047508 xref: MetaCyc:(R)-2-METHYLMALATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008328 name: (R)-dehydropantoate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-4-dehydropantoate + NAD+ + H2O = (R)-3,3-dimethylmalate + NADH + H+." [EC:1.2.1.33, MetaCyc:(R)-DEHYDROPANTOATE-DEHYDROGENASE-RXN] synonym: "(R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity" EXACT [EC:1.2.1.33] synonym: "D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity" EXACT [EC:1.2.1.33] synonym: "D-aldopantoate dehydrogenase activity" EXACT [EC:1.2.1.33] xref: EC:1.2.1.33 xref: GO:0047509 xref: MetaCyc:(R)-DEHYDROPANTOATE-DEHYDROGENASE-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008329 name: (S)-2-methylmalate dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-2-methylmalate = 2-methylfumarate + H2O." [EC:4.2.1.34, MetaCyc:(S)-2-METHYLMALATE-DEHYDRATASE-RXN] synonym: "(+)-citramalate hydro-lyase activity" EXACT [EC:4.2.1.34] synonym: "(+)-citramalic hydro-lyase activity" EXACT [EC:4.2.1.34] synonym: "(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)" EXACT [EC:4.2.1.34] synonym: "(S)-2-methylmalate hydro-lyase activity" EXACT [EC:4.2.1.34] synonym: "citramalate dehydratase activity" EXACT [EC:4.2.1.34] synonym: "L-citramalate hydrolase activity" EXACT [EC:4.2.1.34] synonym: "mesaconase activity" EXACT [EC:4.2.1.34] synonym: "mesaconate hydratase activity" EXACT [EC:4.2.1.34] synonym: "mesaconate mesaconase activity" EXACT [EC:4.2.1.34] xref: EC:4.2.1.34 xref: GO:0047510 xref: MetaCyc:(S)-2-METHYLMALATE-DEHYDRATASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008330 name: (S)-methylmalonyl-CoA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-methylmalonyl-CoA + H2O = methylmalonate + CoA." [EC:3.1.2.17, MetaCyc:(S)-METHYLMALONYL-COA-HYDROLASE-RXN] synonym: "D-methylmalonyl-coenzyme A hydrolase activity" EXACT [EC:3.1.2.17] xref: EC:3.1.2.17 xref: GO:0047511 xref: MetaCyc:(S)-METHYLMALONYL-COA-HYDROLASE-RXN is_a: CCO:F0003105 ! CoA hydrolase activity [Term] id: CCO:F0008331 name: (S,S)-butanediol dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD+ = acetoin + NADH + H+." [EC:1.1.1.76, MetaCyc:(S] synonym: "(S,S)-butane-2,3-diol:NAD+ oxidoreductase activity" EXACT [EC:1.1.1.76] synonym: "L(+)-2,3-butanediol dehydrogenase (L-acetoin forming)" EXACT [EC:1.1.1.76] synonym: "L-BDH" RELATED [EC:1.1.1.76] synonym: "L-butanediol dehydrogenase activity" EXACT [EC:1.1.1.76] xref: EC:1.1.1.76 xref: GO:0047512 xref: MetaCyc:(S is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008332 name: [citrate-(pro-3S)-lyase] thiolesterase activity namespace: molecular_function def: "Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate." [EC:3.1.2.16, MetaCyc:CITRATE-(PRO-3S)-LYASE-THIOLESTERASE-RXN] synonym: "[citrate-(pro-3S)-lyase] thioesterase activity" EXACT [EC:3.1.2.16] synonym: "citrate (pro-3S)-lyase thiolesterase activity" EXACT [] synonym: "citrate lyase deacetylase activity" EXACT [EC:3.1.2.16] synonym: "citrate-(pro-3S)-lyase thioesterase activity" EXACT [EC:3.1.2.16] synonym: "citrate-(pro-3S)-lyase thiolesterase activity" EXACT [EC:3.1.2.16] synonym: "citrate-(pro-3S)-lyase(acetyl-form) hydrolase activity" EXACT [EC:3.1.2.16] xref: EC:3.1.2.16 xref: GO:0047778 xref: MetaCyc:CITRATE-(PRO-3S)-LYASE-THIOLESTERASE-RXN is_a: CCO:F0003361 ! thiolester hydrolase activity [Term] id: CCO:F0008333 name: [phosphorylase] phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate." [EC:3.1.3.17, MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN] synonym: "glycogen phosphorylase phosphatase activity" EXACT [EC:3.1.3.17] synonym: "phosphorylase a phosphatase activity" EXACT [EC:3.1.3.17] synonym: "phosphorylase a phosphohydrolase activity" EXACT [EC:3.1.3.17] synonym: "phosphorylase phosphatase activity" EXACT [] synonym: "PR-enzyme" RELATED [EC:3.1.3.17] synonym: "protein phosphatase C" RELATED [EC:3.1.3.17] synonym: "type 1 protein phosphatase activity" EXACT [EC:3.1.3.17] xref: EC:3.1.3.17 xref: GO:0050196 xref: MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0008334 name: [tyrosine 3-monooxygenase] kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]." [EC:2.7.11.6, MetaCyc:TYROSINE-3-MONOOXYGENASE-KINASE-RXN] synonym: "ATP:tyrosine-3-monoxygenase phosphotransferase activity" EXACT [EC:2.7.11.6] synonym: "pheochromocytoma tyrosine hydroxylase-associated kinase activity" EXACT [EC:2.7.11.6] synonym: "STK4" RELATED [EC:2.7.11.6] synonym: "tyrosine 3-monooxygenase kinase (phosphorylating) activity" EXACT [EC:2.7.11.6] synonym: "tyrosine 3-monooxygenase kinase activity" EXACT [] xref: EC:2.7.11.6 xref: GO:0050369 xref: MetaCyc:TYROSINE-3-MONOOXYGENASE-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0008335 name: [acetyl-CoA carboxylase] kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate." [EC:2.7.11.27, MetaCyc:[ACETYL-COA-CARBOXYLASE\]-KINASE-RXN] synonym: "acetyl coenzyme A carboxylase kinase (phosphorylating) activity" EXACT [EC:2.7.11.27] synonym: "acetyl-CoA carboxylase bound kinase activity" NARROW [EC:2.7.11.27] synonym: "acetyl-CoA carboxylase kinase (AMP-activated) activity" EXACT [EC:2.7.11.27] synonym: "acetyl-CoA carboxylase kinase (cAMP-independent) activity" EXACT [EC:2.7.11.27] synonym: "acetyl-CoA carboxylase kinase 2 activity" NARROW [EC:2.7.11.27] synonym: "acetyl-CoA carboxylase kinase activity" EXACT [EC:2.7.11.27] synonym: "acetyl-CoA carboxylase kinase-2 activity" NARROW [EC:2.7.11.27] synonym: "acetyl-CoA carboxylase kinase-3 (AMP-activated) activity" NARROW [EC:2.7.11.27] synonym: "acetyl-coenzyme A carboxylase kinase activity" EXACT [EC:2.7.11.27] synonym: "ACK2" RELATED [EC:2.7.11.27] synonym: "ACK3" RELATED [EC:2.7.11.27] synonym: "AMPK" RELATED [EC:2.7.11.27] synonym: "ATP:acetyl-CoA carboxylase phosphotransferase activity" EXACT [EC:2.7.11.27] synonym: "I-peptide kinase activity" NARROW [EC:2.7.11.27] synonym: "STK5" RELATED [EC:2.7.11.27] xref: EC:2.7.11.27 xref: GO:0050405 xref: MetaCyc:[ACETYL-COA-CARBOXYLASE\]-KINASE-RXN is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0008336 name: [acetyl-CoA carboxylase]-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate." [EC:3.1.3.44, MetaCyc:[ACETYL-COA-CARBOXYLASE\]-PHOSPHATASE-RXN] synonym: "acetyl-CoA carboxylase-phosphatase activity" EXACT [EC:3.1.3.44] synonym: "acetyl-CoA:carbon-dioxide ligase (ADP-forming)-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.44] xref: EC:3.1.3.44 xref: GO:0050406 xref: MetaCyc:[ACETYL-COA-CARBOXYLASE\]-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0008337 name: [glycogen-synthase-D] phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate." [EC:3.1.3.42, MetaCyc:[GLYCOGEN-SYNTHASE-D\]-PHOSPHATASE-RXN] synonym: "glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] synonym: "glycogen synthase D phosphatase activity" EXACT [EC:3.1.3.42] synonym: "glycogen synthase phosphatase activity" EXACT [EC:3.1.3.42] synonym: "glycogen synthetase phosphatase activity" EXACT [EC:3.1.3.42] synonym: "glycogen-synthase-D phosphatase activity" EXACT [EC:3.1.3.42] synonym: "Mg2+ dependent glycogen synthase phosphatase activity" EXACT [EC:3.1.3.42] synonym: "phosphatase type 2oC" RELATED [EC:3.1.3.42] synonym: "UDP-glucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity" EXACT [EC:3.1.3.42] synonym: "UDP-glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] synonym: "UDPglucose-glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] synonym: "UDPglucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity" EXACT [EC:3.1.3.42] synonym: "uridine diphosphoglucose-glycogen glucosyltransferase phosphatase activity" EXACT [EC:3.1.3.42] xref: EC:3.1.3.42 xref: GO:0050407 xref: MetaCyc:[GLYCOGEN-SYNTHASE-D\]-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0008338 name: [pyruvate kinase]-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate." [EC:3.1.3.49, MetaCyc:[PYRUVATE-KINASE\]-PHOSPHATASE-RXN] synonym: "ATP:pyruvate 2-O-phosphotransferase-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.49] synonym: "pyruvate kinase phosphatase activity" EXACT [EC:3.1.3.49] synonym: "pyruvate kinase-phosphatase activity" EXACT [EC:3.1.3.49] xref: EC:3.1.3.49 xref: GO:0050408 xref: MetaCyc:[PYRUVATE-KINASE\]-PHOSPHATASE-RXN is_a: CCO:F0008387 ! phosphatase activity [Term] id: CCO:F0008339 name: (-)-endo-fenchol synthase activity namespace: molecular_function def: "Catalysis of the reaction: H2O + geranyl-PP = pyrophosphate + (-)-endo-fenchol." [EC:4.2.3.10, MetaCyc:4.2.3.10-RXN] synonym: "(-)-endo-fenchol cyclase activity" EXACT [EC:4.2.3.10] synonym: "geranyl pyrophosphate:(-)-endo-fenchol cyclase activity" EXACT [EC:4.2.3.10] synonym: "geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]" RELATED [EC:4.2.3.10] xref: EC:4.2.3.10 xref: GO:0050437 xref: MetaCyc:4.2.3.10-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0008340 name: (S)-norcoclaurine synthase activity namespace: molecular_function def: "Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O." [EC:4.2.1.78] synonym: "(S)-norlaudanosoline synthase activity" EXACT [EC:4.2.1.78] synonym: "4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine)" EXACT [EC:4.2.1.78] synonym: "4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]" RELATED [EC:4.2.1.78] xref: EC:4.2.1.78 xref: GO:0050474 xref: GO:0050475 xref: MetaCyc:(S)-NORLAUDANOSOLINE-SYNTHASE-RXN is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008341 name: (S)-N-acetyl-1-phenylethylamine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetylphenylethylamine + H2O = phenylethylamine + acetate." [EC:3.5.1.85, MetaCyc:3.5.1.85-RXN] synonym: "(S)-N-acetyl-1-phenylethylamine amidohydrolase activity" EXACT [EC:3.5.1.85] synonym: "(S)-N-acetylphenylethylamine:H2O hydrolase activity" EXACT [EC:3.5.1.85] xref: EC:3.5.1.85 xref: GO:0050536 xref: MetaCyc:3.5.1.85-RXN is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0008342 name: (4S)-limonene synthase activity namespace: molecular_function def: "Catalysis of the reaction: geranyl diphosphate = limonene + diphosphate." [EC:4.2.3.16, MetaCyc:4.2.3.16-RXN] synonym: "(-)-(4S)-limonene synthase activity" EXACT [] synonym: "4S-(-)-limonene synthase activity" EXACT [EC:4.2.3.16] synonym: "geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-(4S)-limonene-forming]" RELATED [EC:4.2.3.16] synonym: "geranyldiphosphate diphosphate lyase (limonene forming)" EXACT [EC:4.2.3.16] synonym: "geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]" RELATED [EC:4.2.3.16] xref: EC:4.2.3.16 xref: GO:0050552 xref: MetaCyc:4.2.3.16-RXN is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0008343 name: (R)-2-hydroxyacid dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+." [EC:1.1.1.272, MetaCyc:1.1.1.272-RXN] subset: gosubset_prok synonym: "(R)-2-hydroxyacid:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.272] synonym: "(R)-sulfolactate:NAD(P)(+) oxidoreductase activity" EXACT [EC:1.1.1.272] synonym: "(R)-sulfolactate:NAD(P)+ oxidoreductase activity" EXACT [EC:1.1.1.272] synonym: "L-sulfolactate dehydrogenase activity" EXACT [EC:1.1.1.272] xref: EC:1.1.1.272 xref: GO:0050578 xref: MetaCyc:1.1.1.272-RXN is_a: CCO:F0003218 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008344 name: (iso)eugenol O-methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol." [EC:2.1.1.146, MetaCyc:2.1.1.146-RXN] synonym: "isoeugenol O-methyltransferase activity" EXACT [] synonym: "S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity" EXACT [EC:2.1.1.146] xref: EC:2.1.1.146 xref: GO:0050630 xref: MetaCyc:2.1.1.146-RXN is_a: CCO:F0001758 ! O-methyltransferase activity [Term] id: CCO:F0008345 name: (R)-2-hydroxyglutarate dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor." [EC:1.1.99.2, MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN] subset: gosubset_prok synonym: "D-2-hydroxyglutarate dehydrogenase activity" EXACT [] xref: EC:1.1.1.- xref: GO:0051990 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0008346 name: type I interferon receptor activity namespace: molecular_function def: "Combining with a type I interferon to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834] synonym: "interferon-alpha receptor activity" NARROW [] synonym: "interferon-alpha/beta receptor activity" NARROW [] synonym: "interferon-beta receptor activity" NARROW [] synonym: "interferon-delta receptor activity" NARROW [] synonym: "interferon-epsilon receptor activity" NARROW [] synonym: "interferon-kappa receptor activity" NARROW [] synonym: "interferon-omega receptor activity" NARROW [] synonym: "interferon-tau receptor activity" NARROW [] synonym: "interferon-zeta receptor activity" NARROW [] xref: GO:0004905 is_a: CCO:F0001251 ! interferon receptor activity is_a: CCO:F0008347 ! type I interferon binding [Term] id: CCO:F0008347 name: type I interferon binding namespace: molecular_function def: "Interacting selectively with a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834] synonym: "interferon-alpha binding" NARROW [] synonym: "interferon-alpha/beta binding" NARROW [] synonym: "interferon-beta binding" NARROW [] synonym: "interferon-delta binding" NARROW [] synonym: "interferon-epsilon binding" NARROW [] synonym: "interferon-kappa binding" NARROW [] synonym: "interferon-omega binding" NARROW [] synonym: "interferon-tau binding" NARROW [] synonym: "interferon-zeta binding" NARROW [] xref: GO:0019962 is_a: CCO:F0004227 ! interferon binding [Term] id: CCO:F0008348 name: nicotinic acid riboside kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + nicotinic acid riboside (NaR) = ADP + nicotinic acid mononucleotide (NaMN)." [PMID:17914902] xref: GO:0034317 is_a: CCO:F0004129 ! nucleoside kinase activity [Term] id: CCO:F0008349 name: alcohol O-acyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule." [GOC:mah] synonym: "acyl-CoA:alcohol O-acyltransferase activity" EXACT [] synonym: "acyl-CoA:ethanol O-acyltransferase" NARROW [] synonym: "acyl-coenzymeA:alcohol O-acyltransferase activity" EXACT [] synonym: "acyl-coenzymeA:ethanol O-acyltransferase activity" NARROW [] synonym: "AEATase activity" NARROW [] synonym: "alcohol acyltransferase activity" EXACT [] xref: GO:0034318 is_a: CCO:F0001850 ! O-acyltransferase activity [Term] id: CCO:F0008350 name: alcohol O-butanoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester." [GOC:mah, PMID:16361250] xref: GO:0034319 is_a: CCO:F0003136 ! O-acetyltransferase activity is_a: CCO:F0008349 ! alcohol O-acyltransferase activity is_a: CCO:F0008354 ! O-butanoyltransferase activity [Term] id: CCO:F0008351 name: alcohol O-hexanoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester." [GOC:mah, PMID:16361250] xref: GO:0034320 is_a: CCO:F0003136 ! O-acetyltransferase activity is_a: CCO:F0008349 ! alcohol O-acyltransferase activity is_a: CCO:F0008355 ! O-hexanoyltransferase activity [Term] id: CCO:F0008352 name: alcohol O-octanoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester." [GOC:mah, PMID:16361250] xref: GO:0034321 is_a: CCO:F0003136 ! O-acetyltransferase activity is_a: CCO:F0003137 ! O-octanoyltransferase activity is_a: CCO:F0008349 ! alcohol O-acyltransferase activity [Term] id: CCO:F0008353 name: alcohol O-decanoyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester." [GOC:mah, PMID:16361250] xref: GO:0034322 is_a: CCO:F0003136 ! O-acetyltransferase activity is_a: CCO:F0008349 ! alcohol O-acyltransferase activity is_a: CCO:F0008356 ! O-decanoyltransferase activity [Term] id: CCO:F0008354 name: O-butanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule." [GOC:mah] xref: GO:0034323 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0008357 ! butanoyltransferase activity [Term] id: CCO:F0008355 name: O-hexanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule." [GOC:mah] xref: GO:0034324 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0008358 ! hexanoyltransferase activity [Term] id: CCO:F0008356 name: O-decanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule." [GOC:mah] xref: GO:0034325 is_a: CCO:F0001850 ! O-acyltransferase activity is_a: CCO:F0008359 ! decanoyltransferase activity [Term] id: CCO:F0008357 name: butanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule." [GOC:mah] xref: GO:0034326 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0008358 name: hexanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule." [GOC:mah] xref: GO:0034327 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0008359 name: decanoyltransferase activity namespace: molecular_function def: "Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule." [GOC:mah] xref: GO:0034328 is_a: CCO:F0001882 ! acyltransferase activity [Term] id: CCO:F0008361 name: misfolded RNA binding namespace: molecular_function def: "Interacting selectively with an RNA molecule that has assumed an incorrect conformation." [GOC:mah, PMID:10393192] synonym: "RNA chaperone" RELATED [] xref: GO:0034336 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0008362 name: short-chain carboxylesterase activity namespace: molecular_function def: "Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms." [GOC:jp] subset: gosubset_prok synonym: "butyrate esterase activity" NARROW [] synonym: "butyryl esterase activity" NARROW [] synonym: "methylbutyrase activity" NARROW [] synonym: "methylbutyrate esterase activity" NARROW [] synonym: "monobutyrase activity" NARROW [] synonym: "propionyl esterase activity" NARROW [] synonym: "short-chain esterase activity" BROAD [] xref: GO:0034338 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0008363 name: type III interferon binding namespace: molecular_function def: "Interacting selectively with a type III interferon. Type III interferons are members of the interferon-lambda gene family." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. synonym: "interferon-lambda binding" EXACT [] xref: GO:0034347 is_a: CCO:F0004227 ! interferon binding [Term] id: CCO:F0008364 name: type III interferon receptor activity namespace: molecular_function def: "Combining with a type III interferon to initiate a change in cell activity. Type III interferons are members of the interferon-lambda gene family." [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557] comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. synonym: "interferon-lambda receptor activity" EXACT [] xref: GO:0034348 is_a: CCO:F0001251 ! interferon receptor activity is_a: CCO:F0008363 ! type III interferon binding [Term] id: CCO:F0008365 name: RNA pyrophosphohydrolase activity namespace: molecular_function def: "Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end." [GOC:jh2, PMID:17612492, PMID:18202662] xref: GO:0034353 is_a: CCO:F0003166 ! pyrophosphatase activity [Term] id: CCO:F0008366 name: FAT10 ligase activity namespace: molecular_function def: "Catalysis of the covalent attachment of the ubiquitin-like protein FAT10 to other proteins." [GOC:mah, PMID:12826404] synonym: "FAT10 conjugating enzyme activity" RELATED [] xref: GO:0019775 is_a: CCO:F0004170 ! small conjugating protein ligase activity [Term] id: CCO:F0008369 name: 4-aminobutyrate:2-oxoglutarate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate." [EC:2.6.1.19, GOC:mah] synonym: "4-aminobutanoate:2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "4-aminobutyrate-2-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "4-aminobutyrate-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "4-aminobutyrate-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] synonym: "4-aminobutyric acid 2-ketoglutaric acid aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "GABA-2-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "GABA-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] synonym: "GABA-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "GABA-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.19] synonym: "GABA-alpha-ketoglutaric acid transaminase activity" EXACT [EC:2.6.1.19] synonym: "GABA-alpha-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "GABA-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "GABA-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyrate-alpha-ketoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyrate-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyrate:alpha-oxoglutarate aminotransferase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyric acid-2-oxoglutarate transaminase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyric acid-alpha-ketoglutarate transaminase activity" EXACT [EC:2.6.1.19] synonym: "gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity" EXACT [EC:2.6.1.19] xref: GO:0034386 is_a: CCO:F0000386 ! 4-aminobutyrate transaminase activity [Term] id: CCO:F0008370 name: 4-aminobutyrate:pyruvate transaminase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine." [EC:2.6.1.19, GOC:mah] synonym: "gamma-aminobutyric acid pyruvate transaminase activity" EXACT [EC:2.6.1.19] xref: GO:0034387 is_a: CCO:F0000386 ! 4-aminobutyrate transaminase activity [Term] id: CCO:F0008371 name: ISG15 ligase activity namespace: molecular_function def: "Catalysis of the covalent attachment of the ubiquitin-like protein ISG15 to other proteins." [GOC:mah, PMID:12826404] synonym: "ISG15 conjugating enzyme activity" EXACT [] xref: GO:0042296 is_a: CCO:F0004170 ! small conjugating protein ligase activity [Term] id: CCO:F0008372 name: 2,3-dihydroxybiphenyl 1,2-dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid." [GOC:jl, PMID:15715866] subset: gosubset_prok synonym: "2,3-dihydroxybiphenyl-1,2-dioxygenase activity" EXACT [] synonym: "BphC" RELATED [] xref: GO:0043898 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0008373 name: bisphosphoglycerate 2-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 3-phosphoglycerate + phosphate." [EC:3.1.3.13] synonym: "2,3-bisphospho-D-glycerate 2-phosphohydrolase activity" EXACT [EC:3.1.3.13] xref: EC:3.1.3.13 xref: GO:0004083 xref: MetaCyc:BISPHOSPHOGLYCERATE-PHOSPHATASE-RXN is_a: CCO:F0000558 ! bisphosphoglycerate phosphatase activity [Term] id: CCO:F0008374 name: protein tyrosine kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate." [EC:2.7.10] subset: gosubset_prok synonym: "protein-tyrosine kinase activity" EXACT [] xref: EC:2.7.10 xref: GO:0004713 xref: MetaCyc:PROTEIN-TYROSINE-KINASE-RXN xref: Reactome:11065 is_a: CCO:F0001043 ! protein kinase activity [Term] id: CCO:F0008375 name: metalloenzyme regulator activity namespace: molecular_function def: "Modulates the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal." [GOC:dph, GOC:tb] xref: GO:0010576 is_a: CCO:F0004354 ! enzyme regulator activity [Term] id: CCO:F0008377 name: bisphosphoglycerate 3-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phosphoglycerate + phosphate." [EC:3.1.3.13, GOC:mah, PMID:18413611] synonym: "2,3-bisphospho-D-glycerate 3-phosphohydrolase activity" EXACT [EC:3.1.3.13] xref: GO:0034417 is_a: CCO:F0000558 ! bisphosphoglycerate phosphatase activity [Term] id: CCO:F0008378 name: L-2-hydroxyglutarate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + H2O2." [PMID:18390652] xref: GO:0034419 is_a: CCO:F0008250 ! (S)-2-hydroxy-acid oxidase activity [Term] id: CCO:F0008379 name: bis(5'-adenosyl)-hexaphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate." [PMID:10085096, PMID:9450008] synonym: "AP(6)A hydrolase activity" EXACT [] synonym: "AP-6-A hydrolase activity" EXACT [] synonym: "AP6A hydrolase activity" EXACT [] synonym: "diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity" EXACT [] xref: GO:0034431 is_a: CCO:F0000937 ! nucleotide diphosphatase activity [Term] id: CCO:F0008380 name: bis(5'-adenosyl)-pentaphosphatase activity namespace: molecular_function def: "Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate." [PMID:10085096, PMID:9450008] synonym: "AP(5)A hydrolase activity" EXACT [] synonym: "AP-5-A hydrolase activity" EXACT [] synonym: "AP5A hydrolase activity" EXACT [] synonym: "diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity" EXACT [] xref: GO:0034432 is_a: CCO:F0000937 ! nucleotide diphosphatase activity [Term] id: CCO:F0008381 name: glycoprotein transporter activity namespace: molecular_function def: "Enables the directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues other than as a moiety of nucleic acid, into, out of, within or between cells." [GOC:mah, GOC:rl] xref: GO:0034437 is_a: CCO:F0001997 ! protein transporter activity [Term] id: CCO:F0008382 name: phosphoserine:homoserine phosphotransferase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine." [GOC:jl, PMID:14699121] subset: gosubset_prok synonym: "thrH" RELATED [] xref: EC:2.7.1.- xref: GO:0043899 xref: IMG:02616 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0008383 name: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate, with a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*±6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S." [EC:2.8.2.23] synonym: "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase" BROAD [EC:2.8.2.23] synonym: "3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity" EXACT [EC:2.8.2.23] synonym: "3-OST-1 activity" EXACT [EC:2.8.2.23] synonym: "glucosaminyl 3-O-sulfotransferase activity" EXACT [EC:2.8.2.23] synonym: "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" EXACT [EC:2.8.2.23] synonym: "heparin-glucosamine 3-O-sulfotransferase activity" RELATED [] synonym: "heparin-glucosamine 3-O-sulphotransferase activity" RELATED [] synonym: "isoform/isozyme 1 (3-OST-1, HS3ST1)" RELATED [EC:2.8.2.23] xref: EC:2.8.2.23 xref: GO:0008467 xref: MetaCyc:2.8.2.23-RXN is_a: CCO:F0008398 ! heparan sulfate sulfotransferase activity [Term] id: CCO:F0008384 name: holo-[acyl-carrier-protein] synthase activity namespace: molecular_function def: "Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form." [EC:2.7.8.7, PMID:10320345, PMID:11867633, PMID:8939709] subset: gosubset_prok synonym: "4'-phosphopantetheinyl transferase activity" EXACT [EC:2.7.8.7] synonym: "4'-phosphopantetheinyltransferase activity" EXACT [] synonym: "AcpS" RELATED [EC:2.7.8.7] synonym: "ACPS activity" RELATED [EC:2.7.8.7] synonym: "acyl carrier protein holoprotein (holo-ACP) synthetase activity" EXACT [EC:2.7.8.7] synonym: "acyl carrier protein synthase activity" RELATED [EC:2.7.8.7] synonym: "acyl carrier protein synthetase activity" RELATED [EC:2.7.8.7] synonym: "alpha-aminoadipate reductase phosphopantetheinyl transferase activity" EXACT [] synonym: "alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity" EXACT [EC:2.7.8.7] synonym: "alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity" EXACT [EC:2.7.8.7] synonym: "CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity" EXACT [EC:2.7.8.7] synonym: "CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity" EXACT [EC:2.7.8.7] synonym: "coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity" EXACT [EC:2.7.8.7] synonym: "holo-[acyl-carrier-protein] synthase activity" NARROW [] synonym: "holo-[peptidyl-carrier protein] synthase activity" NARROW [] synonym: "holo-ACP synthase activity" RELATED [EC:2.7.8.7] synonym: "holo-ACP synthetase activity" RELATED [EC:2.7.8.7] synonym: "holo-acyl-carrier-protein synthase activity" EXACT [EC:2.7.8.7] synonym: "holosynthase activity" RELATED [EC:2.7.8.7] synonym: "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity" NARROW [EC:2.7.8.7] synonym: "P-pant transferase activity" EXACT [EC:2.7.8.7] synonym: "phosphopantetheinyltransferase activity" EXACT [] synonym: "PPTase activity" EXACT [EC:2.7.8.7] xref: EC:2.7.8.7 xref: GO:0008897 xref: GO:0008958 xref: MetaCyc:HOLO-ACP-SYNTH-RXN is_a: CCO:F0003352 ! phosphotransferase activity, for other substituted phosphate groups [Term] id: CCO:F0008385 name: metalloenzyme activator activity namespace: molecular_function def: "Increases the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal." [GOC:dph, GOC:tb] xref: GO:0010577 is_a: CCO:F0001691 ! enzyme activator activity is_a: CCO:F0008375 ! metalloenzyme regulator activity [Term] id: CCO:F0008386 name: thrombin receptor activity, G-protein coupled namespace: molecular_function def: "Combining with thrombin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state." [GOC:dph, GOC:tb] xref: GO:0010655 is_a: CCO:F0001980 ! peptide receptor activity, G-protein coupled is_a: CCO:F0002550 ! thrombin receptor activity [Term] id: CCO:F0008387 name: phosphatase activity namespace: molecular_function def: "Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate." [http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "phosphatase" RELATED [] synonym: "phosphoric monoester hydrolase activity" EXACT [] xref: EC:3.1.3 xref: GO:0016302 xref: GO:0016791 is_a: CCO:F0005685 ! phosphoric ester hydrolase activity [Term] id: CCO:F0008388 name: Atg8 ligase activity namespace: molecular_function def: "Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate." [GOC:mah, PMID:12826404] synonym: "APG8 conjugating enzyme activity" EXACT [] synonym: "APG8 ligase activity" EXACT [] synonym: "Atg8 conjugating enzyme activity" EXACT [] xref: GO:0019776 is_a: CCO:F0003438 ! ligase activity, forming carbon-nitrogen bonds [Term] id: CCO:F0008389 name: Atg12 ligase activity namespace: molecular_function def: "Catalysis of the covalent attachment of the ubiquitin-like protein Atg12 to other proteins." [GOC:mah, PMID:12826404] synonym: "APG12 conjugating enzyme activity" EXACT [] synonym: "APG12 ligase activity" EXACT [] synonym: "Atg12 conjugating enzyme activity" RELATED [] xref: GO:0019777 is_a: CCO:F0004170 ! small conjugating protein ligase activity [Term] id: CCO:F0008390 name: ubiquitin-ubiquitin ligase activity namespace: molecular_function def: "Catalysis of the reaction: Catalysis of the reaction: ATP + ubiquitin + protein N-ubiquityl(n)lysine = AMP + diphosphate + protein N-ubiquityl(n+1)lysine, i.e. the ligation of ubiquitin moieties, via isopeptide bonds, to extend the length of the multiubiquitin chain attached to a substrate protein." [GOC:mah, GOC:mcc, PMID:10089879, PMID:17190603] synonym: "E4" EXACT [] xref: GO:0034450 is_a: CCO:F0001198 ! ubiquitin-protein ligase activity [Term] id: CCO:F0008391 name: dynactin binding namespace: molecular_function def: "Interacting selectively with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity." [GOC:mah] xref: GO:0034452 is_a: CCO:F0001705 ! cytoskeletal protein binding [Term] id: CCO:F0008392 name: 3'-5' RNA helicase activity namespace: molecular_function def: "Catalysis of the unwinding of an RNA helix in the direction 3' to 5'." [GOC:mah] synonym: "3' to 5' RNA helicase activity" EXACT [] xref: GO:0034458 is_a: CCO:F0000309 ! RNA helicase activity [Term] id: CCO:F0008393 name: ATP-dependent 3'-5' RNA helicase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + H2O = ADP + phosphate, driving the unwinding of an RNA helix in the direction 3' to 5'." [GOC:jp] synonym: "ATP-dependent 3' to 5' RNA helicase activity" EXACT [] xref: GO:0034459 is_a: CCO:F0000488 ! ATP-dependent RNA helicase activity is_a: CCO:F0008392 ! 3'-5' RNA helicase activity [Term] id: CCO:F0008394 name: phosphatidylglycerol phospholipase C activity namespace: molecular_function def: "Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate." [GOC:mah, PMID:18434318] xref: GO:0034479 is_a: CCO:F0001003 ! phospholipase C activity [Term] id: CCO:F0008395 name: phosphatidylcholine phospholipase C activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate." [EC:3.1.4.3, GOC:mah] subset: gosubset_prok synonym: "alpha-toxin" NARROW [EC:3.1.4.3] synonym: "Clostridium oedematiens beta- and gamma-toxins activity" NARROW [EC:3.1.4.3] synonym: "Clostridium welchii alpha-toxin activity" NARROW [EC:3.1.4.3] synonym: "heat-labile hemolysin" NARROW [EC:3.1.4.3] synonym: "lipophosphodiesterase I activity" EXACT [EC:3.1.4.3] synonym: "phosphatidylcholine cholinephosphohydrolase activity" EXACT [EC:3.1.4.3] synonym: "phospholipase C, acting on phosphatidylcholine" EXACT [] xref: EC:3.1.4.3 xref: GO:0034480 xref: MetaCyc:PHOSPHOLIPASE-C-RXN xref: Reactome:11457 is_a: CCO:F0001003 ! phospholipase C activity [Term] id: CCO:F0008396 name: chondroitin sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate." [EC:2.8.2.17, EC:2.8.2.5, GOC:mah] xref: GO:0034481 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0008397 name: chondroitin 2-O-sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues." [PMID:17227754] synonym: "chondroitin 2-O-sulphotransferase activity" EXACT [] synonym: "chondroitin 2-sulfotransferase activity" EXACT [] xref: EC:2.8.2.17 xref: GO:0034482 xref: MetaCyc:CHONDROITIN-6-SULFOTRANSFERASE-RXN is_a: CCO:F0008396 ! chondroitin sulfotransferase activity [Term] id: CCO:F0008398 name: heparan sulfate sulfotransferase activity namespace: molecular_function def: "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate." [GOC:mah] xref: GO:0034483 is_a: CCO:F0001748 ! sulfotransferase activity [Term] id: CCO:F0008399 name: phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: phosphatidylinositol 3,4,5-trisphosphate + H2O = phosphatidylinositol 3,4-bisphosphate + phosphate." [GOC:pf] xref: GO:0034485 is_a: CCO:F0000843 ! phosphoinositide 5-phosphatase activity is_a: CCO:F0008467 ! phosphatidylinositol trisphosphate phosphatase activity [Term] id: CCO:F0008400 name: U3 snoRNA binding namespace: molecular_function def: "Interacting selectively with U3 small nucleolar RNA." [GOC:mah] xref: GO:0034511 is_a: CCO:F0004450 ! snoRNA binding [Term] id: CCO:F0008401 name: box C/D snoRNA binding namespace: molecular_function def: "Interacting selectively with box C/D small nucleolar RNA." [GOC:mah] xref: GO:0034512 is_a: CCO:F0004450 ! snoRNA binding [Term] id: CCO:F0008402 name: box H/ACA snoRNA binding namespace: molecular_function def: "Interacting selectively with box H/ACA small nucleolar RNA." [GOC:mah] xref: GO:0034513 is_a: CCO:F0004450 ! snoRNA binding [Term] id: CCO:F0008403 name: 2-naphthaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+." [UM-BBD_reactionID:r0772] xref: EC:1.2.1.- xref: GO:0034520 xref: UM-BBD_enzymeID:e0483 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008404 name: 1-naphthoic acid dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+." [UM-BBD_reactionID:r0773] xref: EC:1.14.12.- xref: GO:0034521 xref: UM-BBD_enzymeID:e0484 is_a: CCO:F0003291 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor [Term] id: CCO:F0008405 name: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2H+ + 2e-." [UM-BBD_reactionID:r0774] xref: EC:1.1.-.- xref: GO:0034522 xref: UM-BBD_enzymeID:e0485 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0008406 name: 3-formylsalicylate oxidase activity namespace: molecular_function def: "Catalysis of the reaction: 3-formylsalicylic acid +O2 + H2O = 2-hydroxyisophthalic acid +H2O2." [UM-BBD_reactionID:r0777] xref: EC:1.2.3.- xref: GO:0034523 xref: UM-BBD_enzymeID:e0486 is_a: CCO:F0003225 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor [Term] id: CCO:F0008407 name: 2-hydroxyisophthalate decarboxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2." [UM-BBD_reactionID:r07760] xref: EC:4.1.1.- xref: GO:0034524 xref: UM-BBD_enzymeID:e0487 is_a: CCO:F0003398 ! carboxy-lyase activity [Term] id: CCO:F0008408 name: 1-naphthaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+." [UM-BBD_reactionID:r0787] xref: EC:1.2.1.- xref: GO:0034525 xref: UM-BBD_enzymeID:e0489 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008409 name: 2-methylnaphthalene hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAH+ + H2O." [UM-BBD_reactionID:r0788] xref: EC:1.14.13.- xref: GO:0034526 xref: UM-BBD_enzymeID:e0490 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008410 name: 1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene +O2 = 2-carboxy-2-hydroxy-8-carboxychromene." [UM-BBD_reactionID:r0790] xref: EC:1.13.-.- xref: GO:0034527 xref: UM-BBD_enzymeID:e0491 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Term] id: CCO:F0008411 name: 2-carboxy-2-hydroxy-8-carboxychromene isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate." [UM-BBD_reactionID:r0791] xref: EC:5.3.99.- xref: GO:0034528 xref: UM-BBD_enzymeID:e0492 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0008412 name: 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate." [UM-BBD_reactionID:r0792] xref: EC:4.1.2.- xref: GO:0034529 xref: UM-BBD_enzymeID:e0493 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0008413 name: 4-hydroxymethylsalicyaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2H+." [UM-BBD_reactionID:r0767] xref: EC:1.2.1.- xref: GO:0034530 xref: UM-BBD_enzymeID:e0495 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008414 name: 2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde." [UM-BBD_reactionID:r0766] xref: EC:4.1.2.- xref: GO:0034531 xref: UM-BBD_enzymeID:e0496 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0008415 name: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate." [UM-BBD_reactionID:r0765] xref: EC:5.3.99.- xref: GO:0034532 xref: UM-BBD_enzymeID:e0497 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0008416 name: 1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate." [UM-BBD_reactionID:r0764] xref: EC:1.13.-.- xref: GO:0034533 xref: UM-BBD_enzymeID:e0498 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Term] id: CCO:F0008417 name: 1-methylnaphthalene hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O." [UM-BBD_reactionID:r0795] xref: EC:1.14.13.- xref: GO:0034534 xref: UM-BBD_enzymeID:e0500 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008418 name: 1,2-dihydroxy-8-methylnaphthalene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+." [UM-BBD_reactionID:r0781] xref: EC:1.13.-.- xref: GO:0034535 xref: UM-BBD_enzymeID:e0501 is_a: CCO:F0003285 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [Term] id: CCO:F0008419 name: 2-hydroxy-8-methylchromene-2-carboxylate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate." [UM-BBD_reactionID:r0782] xref: EC:5.3.99.- xref: GO:0034536 xref: UM-BBD_enzymeID:e0502 is_a: CCO:F0003422 ! intramolecular oxidoreductase activity [Term] id: CCO:F0008420 name: 2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity namespace: molecular_function def: "Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde." [UM-BBD_reactionID:r0783] xref: EC:4.1.2.- xref: GO:0034537 xref: UM-BBD_enzymeID:e0503 is_a: CCO:F0003399 ! aldehyde-lyase activity [Term] id: CCO:F0008421 name: 3-methylsalicylaldehyde dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+." [UM-BBD_reactionID:r0784] xref: EC:1.2.1.- xref: GO:0034538 xref: UM-BBD_enzymeID:e0504 is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008422 name: 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,3',5,5'-Tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr." [UM-BBD_reactionID:r0821] xref: EC:1.97.1.- xref: GO:0034539 xref: UM-BBD_enzymeID:e0510 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008423 name: 3-monobromobisphenol A reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-monobromobisphenol A+ 2 H+ + 2 e- = bisphenol A + HBr." [UM-BBD_reactionID:r0824] xref: EC:1.97.1.- xref: GO:0034540 xref: UM-BBD_enzymeID:e0513 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008424 name: dimethylarsinite methyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH." [UM-BBD_reactionID:r0806] xref: EC:2.1.1.- xref: GO:0034541 xref: UM-BBD_enzymeID:e0516 is_a: CCO:F0001755 ! methyltransferase activity [Term] id: CCO:F0008425 name: trimethylarsine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O." [UM-BBD_reactionID:r0807] xref: EC:1.97.1.- xref: GO:0034542 xref: UM-BBD_enzymeID:e0517 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008426 name: 5-aminosalicylate dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate." [UM-BBD_reactionID:r0809] xref: EC:1.13.11.- xref: GO:0034543 xref: UM-BBD_enzymeID:e0518 is_a: CCO:F0003286 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [Term] id: CCO:F0008427 name: trans-ACOHDA hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3." [UM-BBD_reactionID:r0810] xref: EC:3.5.99.- xref: GO:0034544 xref: UM-BBD_enzymeID:e0519 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0008428 name: fumarylpyruvate hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+." [UM-BBD_reactionID:r0811] xref: EC:3.7.1.- xref: GO:0034545 xref: UM-BBD_enzymeID:e0520 is_a: CCO:F0003390 ! hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances [Term] id: CCO:F0008429 name: 2,4-dichloroaniline reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl." [UM-BBD_reactionID:r0819] xref: EC:1.97.1.- xref: GO:0034546 xref: UM-BBD_enzymeID:e0521 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008430 name: N-cyclopropylmelamine deaminase activity namespace: molecular_function def: "Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3." [UM-BBD_reactionID:r0825] xref: EC:3.5.4.- xref: GO:0034547 xref: UM-BBD_enzymeID:e0524 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [Term] id: CCO:F0008431 name: N-cyclopropylammeline deaminase activity namespace: molecular_function def: "Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3." [UM-BBD_reactionID:r0826] xref: EC:3.5.4.- xref: GO:0034548 xref: UM-BBD_enzymeID:e0525 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [Term] id: CCO:F0008432 name: N-cyclopropylammelide alkylamino hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid." [UM-BBD_reactionID:r082750] xref: EC:3.5.4.- xref: GO:0034549 xref: UM-BBD_enzymeID:e0526 is_a: CCO:F0003383 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [Term] id: CCO:F0008433 name: dimethylarsinate reductase activity namespace: molecular_function def: "Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O." [UM-BBD_reactionID:r0838] xref: EC:1.97.1.- xref: GO:0034550 xref: UM-BBD_enzymeID:e0529 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008434 name: 3,3',5-tribromobisphenol A reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr." [UM-BBD_reactionID:r0842] xref: EC:1.97.1.- xref: GO:0034554 xref: UM-BBD_enzymeID:e0532 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008435 name: 3,3'-dibromobisphenol A reductive dehalogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3,3'-dibromobisphenol A + 2H+ + 2 e- = 3-monobromobisphenol A + HBr." [UM-BBD_reactionID:r0844] xref: EC:1.97.1.- xref: GO:0034555 xref: UM-BBD_enzymeID:e0533 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008436 name: nitrobenzoate nitroreductase activity namespace: molecular_function def: "Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+." [UM-BBD_reactionID:r0849] xref: EC:1.7.1.- xref: GO:0034556 xref: UM-BBD_enzymeID:e0536 is_a: CCO:F0003255 ! oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor [Term] id: CCO:F0008437 name: o-hydroxylaminobenzoate nitroreductase activity namespace: molecular_function def: "Catalysis of the reaction: o-hydroxylaminobenzoate + 2 H+ + 2 e-= 2-aminobenzoate + H2O." [UM-BBD_reactionID:r0850] xref: EC:1.4.-.- xref: GO:0034557 xref: UM-BBD_enzymeID:e0537 is_a: CCO:F0003238 ! oxidoreductase activity, acting on the CH-NH2 group of donors [Term] id: CCO:F0008438 name: technetium (VII) reductase activity namespace: molecular_function def: "Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-." [UM-BBD_reactionID:r0859] xref: EC:1.12.-.- xref: GO:0034558 xref: UM-BBD_enzymeID:e0542 is_a: CCO:F0003281 ! oxidoreductase activity, acting on hydrogen as donor [Term] id: CCO:F0008439 name: bisphenol A hydroxylase B activity namespace: molecular_function def: "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O." [UM-BBD_reactionID:r0860] xref: EC:1.14.-.- xref: GO:0034559 xref: UM-BBD_enzymeID:e0543 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0008440 name: bisphenol A hydroxylase A activity namespace: molecular_function def: "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O." [UM-BBD_reactionID:r0861] xref: EC:1.14.13.- xref: GO:0034560 xref: UM-BBD_enzymeID:e0544 is_a: CCO:F0003292 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008441 name: 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity namespace: molecular_function def: "Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O." [UM-BBD_reactionID:r0862] xref: EC:4.2.1.- xref: GO:0034561 xref: UM-BBD_enzymeID:e0545 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008442 name: 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity namespace: molecular_function def: "Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O." [UM-BBD_reactionID:r0864] xref: EC:1.14.-.- xref: GO:0034562 xref: UM-BBD_enzymeID:e0547 is_a: CCO:F0003288 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Term] id: CCO:F0008443 name: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2e-." [UM-BBD_reactionID:r0867] xref: EC:1.13.-.- xref: GO:0034563 xref: UM-BBD_enzymeID:e0548 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008444 name: 4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity namespace: molecular_function def: "Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-." [UM-BBD_reactionID:r0866] xref: EC:1.3.-.- xref: GO:0034564 xref: UM-BBD_enzymeID:e0549 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0008445 name: 1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol." [UM-BBD_reactionID:r0872] xref: EC:3.5.99.- xref: GO:0034565 xref: UM-BBD_enzymeID:e0552 is_a: CCO:F0003379 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Term] id: CCO:F0008446 name: formamide hydrolase activity namespace: molecular_function def: "Catalysis of the reaction: formamide + H2O = formate + NH3 + H+." [UM-BBD_reactionID:r0873] xref: EC:3.5.1.- xref: GO:0034566 xref: UM-BBD_enzymeID:e0554 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0008447 name: chromate reductase activity namespace: molecular_function def: "Catalysis of the reaction: chromate = chromium (III)." [UM-BBD_reactionID:r0884] xref: EC:1.97.1.- xref: GO:0034567 xref: UM-BBD_enzymeID:e0556 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008448 name: isoproturon dimethylaminedehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-." [UM-BBD_reactionID:r0892] xref: EC:1.5.99.- xref: GO:0034568 xref: UM-BBD_enzymeID:e0561 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0008449 name: monodemethylisoproturon dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2H+ + 2 e-." [UM-BBD_reactionID:r0893] xref: EC:1.17.99.- xref: GO:0034569 xref: UM-BBD_enzymeID:e0562 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0008450 name: hydroxymonomethylisoproturon dimethylaminedehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-." [UM-BBD_reactionID:r0894] xref: EC:1.5.99.- xref: GO:0034570 xref: UM-BBD_enzymeID:e0563 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0008451 name: 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid." [UM-BBD_reactionID:r0895] xref: EC:3.5.1.- xref: GO:0034571 xref: UM-BBD_enzymeID:e0564 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0008452 name: monodemethylisoproturon dimethylaminedehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-." [UM-BBD_reactionID:r0897] xref: EC:1.5.99.- xref: GO:0034572 xref: UM-BBD_enzymeID:e0565 is_a: CCO:F0003244 ! oxidoreductase activity, acting on the CH-NH group of donors [Term] id: CCO:F0008453 name: didemethylisoproturon amidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline." [UM-BBD_reactionID:r0898] xref: EC:3.5.1.- xref: GO:0034573 xref: UM-BBD_enzymeID:e0566 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0008454 name: didemethylisoproturon dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-." [UM-BBD_reactionID:r0899] xref: EC:1.17.99.- xref: GO:0034574 xref: UM-BBD_enzymeID:e0567 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0008455 name: 4-isopropylaniline dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-." [UM-BBD_reactionID:r0901] xref: EC:1.17.99.- xref: GO:0034575 xref: UM-BBD_enzymeID:e0569 is_a: CCO:F0003307 ! oxidoreductase activity, acting on CH or CH2 groups [Term] id: CCO:F0008456 name: N-isopropylacetanilide amidohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate." [UM-BBD_reactionID:r0913] xref: EC:3.5.1.- xref: GO:0034576 xref: UM-BBD_enzymeID:e0570 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0008457 name: N-isopropylacetaniline monooxygenase activity namespace: molecular_function def: "Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone." [UM-BBD_reactionID:r0914] xref: EC:1.14.15.- xref: GO:0034577 xref: UM-BBD_enzymeID:e0571 is_a: CCO:F0003296 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen [Term] id: CCO:F0008458 name: limonene 8-hydratase activity namespace: molecular_function def: "Catalysis of the reaction: limonene + H2O = alpha-terpineol." [UM-BBD_reactionID:r0916] xref: EC:4.2.1.- xref: GO:0034578 xref: UM-BBD_enzymeID:e0572 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008459 name: (1-methylpentyl)succinate synthase activity namespace: molecular_function def: "Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate." [UM-BBD_reactionID:r0920] xref: EC:4.1.99.- xref: GO:0034579 xref: UM-BBD_enzymeID:e0573 is_a: CCO:F0003397 ! carbon-carbon lyase activity [Term] id: CCO:F0008460 name: 4-methyloctanoyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0924] xref: EC:1.3.99.- xref: GO:0034580 xref: UM-BBD_enzymeID:e0577 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:F0008461 name: 4-methyloct-2-enoyl-CoA hydratase activity namespace: molecular_function def: "Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA." [UM-BBD_reactionID:r0925] xref: EC:4.2.1.- xref: GO:0034581 xref: UM-BBD_enzymeID:e0578 is_a: CCO:F0003402 ! hydro-lyase activity [Term] id: CCO:F0008462 name: 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity namespace: molecular_function def: "Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-." [UM-BBD_reactionID:r0926] xref: EC:1.1.-.- xref: GO:0034582 xref: UM-BBD_enzymeID:e0579 is_a: CCO:F0003216 ! oxidoreductase activity, acting on CH-OH group of donors [Term] id: CCO:F0008463 name: 21U-RNA binding namespace: molecular_function def: "Interacting selectively with a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome." [GOC:kmv] xref: GO:0034583 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0008464 name: piRNA binding namespace: molecular_function def: "Interacting selectively with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism." [GOC:kmv] synonym: "Piwi-associated RNA binding" EXACT [] xref: GO:0034584 is_a: CCO:F0000308 ! RNA binding [Term] id: CCO:F0008465 name: L-hydroxyproline transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of L-hydroxyproline from one side of a membrane to the other." [GOC:mah, PMID:14502423] synonym: "4-hydroxyproline transmembrane transporter activity" BROAD [] xref: GO:0034590 is_a: CCO:F0002652 ! neutral amino acid transmembrane transporter activity is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity [Term] id: CCO:F0008466 name: phosphatidylinositol bisphosphate phosphatase activity namespace: molecular_function def: "Catalysis of the removal of one of the two phosphate groups of a phosphatidylinositol bisphosphate." [GOC:mah] synonym: "diphosphoinositide phosphatase activity" RELATED [] synonym: "phosphatidyl-inositol-bisphosphate phosphatase activity" EXACT [] synonym: "phosphatidylinositol-bisphosphatase activity" RELATED [] synonym: "triphosphoinositide phosphatase activity" RELATED [] synonym: "triphosphoinositide phosphomonoesterase activity" RELATED [] xref: GO:0034593 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0008467 name: phosphatidylinositol trisphosphate phosphatase activity namespace: molecular_function def: "Catalysis of the removal of one of the three phosphate groups of a phosphatidylinositol trisphosphate." [GOC:mah] xref: GO:0034594 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0008468 name: phosphoinositide 4-phosphatase activity namespace: molecular_function def: "Catalysis of the removal the of the 4-phosphate group of a phosphatidylinositol phosphate." [GOC:mah] xref: GO:0034596 is_a: CCO:F0000841 ! inositol or phosphatidylinositol phosphatase activity [Term] id: CCO:F0008469 name: phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate." [GOC:mah] synonym: "1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity" EXACT [] synonym: "D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity" EXACT [] synonym: "inositol polyphosphate 4-phosphatase type II activity" RELATED [EC:3.1.3.66] synonym: "phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity" EXACT [] xref: EC:3.1.3.66 xref: GO:0034597 xref: MetaCyc:3.1.3.66-RXN is_a: CCO:F0005684 ! lipid phosphatase activity is_a: CCO:F0008466 ! phosphatidylinositol bisphosphate phosphatase activity is_a: CCO:F0008468 ! phosphoinositide 4-phosphatase activity [Term] id: CCO:F0008470 name: phosphothreonine lyase activity namespace: molecular_function def: "Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product." [PMID:17303758, PMID:18084305] xref: GO:0034598 is_a: CCO:F0003404 ! carbon-oxygen lyase activity, acting on phosphates [Term] id: CCO:F0008471 name: oxoglutarate dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H." [GOC:mah] xref: EC:1.2.1.52 xref: GO:0034601 xref: MetaCyc:OXOGLUTARATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008472 name: oxoglutarate dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH." [GOC:mah] xref: EC:1.2.1.52 xref: GO:0034602 xref: MetaCyc:OXOGLUTARATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0008471 ! oxoglutarate dehydrogenase [NAD(P)+] activity [Term] id: CCO:F0008473 name: pyruvate dehydrogenase [NAD(P)+] activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H." [GOC:mah] xref: EC:1.2.1.51 xref: GO:0034603 xref: MetaCyc:PYRUVATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0001103 ! pyruvate dehydrogenase activity is_a: CCO:F0003222 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Term] id: CCO:F0008474 name: pyruvate dehydrogenase (NAD+) activity namespace: molecular_function def: "Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH." [GOC:mah] xref: EC:1.2.1.51 xref: GO:0034604 xref: MetaCyc:PYRUVATE-DEHYDROGENASE-(NADP+)-RXN is_a: CCO:F0008473 ! pyruvate dehydrogenase [NAD(P)+] activity [Term] id: CCO:F0008475 name: oligodeoxyribonucleotidase activity namespace: molecular_function def: "Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates." [GOC:mah] synonym: "DNA oligonucleotidase activity" EXACT [] xref: GO:0034610 is_a: CCO:F0000932 ! deoxyribonuclease activity is_a: CCO:F0002282 ! oligonucleotidase activity [Term] id: CCO:F0008476 name: oligoribonucleotidase activity namespace: molecular_function def: "Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates." [GOC:mah] synonym: "RNA oligonucleotidase activity" EXACT [] xref: GO:0034611 is_a: CCO:F0000934 ! ribonuclease activity is_a: CCO:F0002282 ! oligonucleotidase activity [Term] id: CCO:F0008477 name: tetrahydrobiopterin binding namespace: molecular_function def: "Interacting selectively with a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions." [ChEBI:15372, GOC:mah, GOC:rl] synonym: "BH4 binding" EXACT [] synonym: "H4biopterin binding" EXACT [] synonym: "sapropterin binding" EXACT [] xref: GO:0034617 is_a: CCO:F0007988 ! coenzyme binding [Term] id: CCO:F0008478 name: arginine binding namespace: molecular_function def: "Interacting selectively with 2-amino-5-(carbamimidamido)pentanoic acid." [ChEBI:29016, GOC:rl] synonym: "aminopentanoic acid binding" RELATED [] synonym: "Arg binding" EXACT [] xref: GO:0034618 is_a: CCO:F0003212 ! amino acid binding [Term] id: CCO:F0008479 name: retinol transporter activity namespace: molecular_function def: "Enables the directed movement of retinol into, out of, within or between cells. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A." [GOC:mah, GOC:vk] synonym: "vitamin A1 transporter activity" EXACT [] xref: GO:0034632 is_a: CCO:F0008065 ! vitamin transporter activity [Term] id: CCO:F0008480 name: glutathione transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of glutathione, the tripeptide glutamylcysteinylglycine, across a membrane into, out of, within or between cells." [GOC:mah] xref: GO:0034634 is_a: CCO:F0004310 ! substrate-specific transmembrane transporter activity [Term] id: CCO:F0008481 name: L-amino acid efflux transmembrane transporter activity namespace: molecular_function def: "Catalysis of the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane." [GOC:mah] synonym: "L-amino acid efflux permease activity" EXACT [] synonym: "L-amino acid export transporter activity" EXACT [] xref: GO:0034639 is_a: CCO:F0002653 ! L-amino acid transmembrane transporter activity is_a: CCO:F0002942 ! efflux transmembrane transporter activity [Term] id: CCO:F0008482 name: histone demethylase activity (H3-trimethyl-K4 specific) namespace: molecular_function def: "Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:17550896] synonym: "histone demethylase activity (H3-K4-me3 specific)" EXACT [] xref: GO:0034647 is_a: CCO:F0004999 ! histone demethylase activity (H3-K4 specific) [Term] id: CCO:F0008483 name: histone demethylase activity (H3-dimethyl-K4 specific) namespace: molecular_function def: "Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:17550896] synonym: "histone demethylase activity (H3-K4-me2 specific)" EXACT [] xref: GO:0034648 is_a: CCO:F0004999 ! histone demethylase activity (H3-K4 specific) [Term] id: CCO:F0008484 name: histone demethylase activity (H3-monomethyl-K4 specific) namespace: molecular_function def: "Catalysis of the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein." [GOC:mah, PMID:17550896] synonym: "histone demethylase activity (H3-K4-me1 specific)" EXACT [] xref: GO:0034649 is_a: CCO:F0004999 ! histone demethylase activity (H3-K4 specific) [Term] id: CCO:F0008485 name: fructose 1,6-bisphosphate 1-phosphatase activity namespace: molecular_function def: "Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [EC:3.1.3.11] subset: gosubset_prok synonym: "D-fructose 1,6-diphosphatase activity" EXACT [EC:3.1.3.11] synonym: "D-fructose-1,6-bisphosphate 1-phosphohydrolase activity" EXACT [EC:3.1.3.11] synonym: "D-fructose-1,6-bisphosphate phosphatase activity" EXACT [EC:3.1.3.11] synonym: "FBPase activity" EXACT [EC:3.1.3.11] synonym: "fructose 1,6-bisphosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose 1,6-bisphosphate phosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose 1,6-diphosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose 1,6-diphosphate phosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose bisphosphate phosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose diphosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose diphosphate phosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose-1,6-bisphosphatase activity" EXACT [EC:3.1.3.11] synonym: "fructose-bisphosphatase activity" BROAD [EC:3.1.3.00] synonym: "hexose bisphosphatase activity" EXACT [EC:3.1.3.11] synonym: "hexose diphosphatase activity" EXACT [EC:3.1.3.11] synonym: "hexosediphosphatase activity" BROAD [EC:3.1.3.11] xref: EC:3.1.3.11 xref: GO:0042132 xref: MetaCyc:F16BDEPHOS-RXN xref: Reactome:9272 is_a: CCO:F0004126 ! carbohydrate phosphatase activity [Term] id: CCO:F0008486 name: isochorismate pyruvate lyase activity namespace: molecular_function def: "Catalysis of the reaction: isochorismate = salicylate + pyruvate." [GOC:jl, PMID:16248620] subset: gosubset_prok synonym: "IPL" EXACT [] synonym: "isochorismate-pyruvate lyase activity" EXACT [] xref: EC:4.1.3.- xref: GO:0043904 xref: IMG:02661 is_a: CCO:F0003400 ! oxo-acid-lyase activity [Term] id: CCO:F0008487 name: Ser-tRNA(Thr) hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr)." [GOC:jl, PMID:15240874] subset: gosubset_prok synonym: "Ser-tRNAThr hydrolase activity" EXACT [] xref: EC:3.1.1.- xref: GO:0043905 xref: IMG:02667 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0008488 name: Ala-tRNA(Pro) hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro)." [GOC:jl, PMID:14663147] subset: gosubset_prok synonym: "Ala-tRNAPro hydrolase activity" EXACT [] xref: EC:3.1.1.- xref: GO:0043906 xref: IMG:02668 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0008489 name: Cys-tRNA(Pro) hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro)." [GOC:jl, PMID:15886196] subset: gosubset_prok synonym: "Cys-tRNA(Pro) deacetylase activity" EXACT [] synonym: "Cys-tRNAPro hydrolase activity" EXACT [] xref: EC:3.1.1.- xref: GO:0043907 xref: IMG:02669 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0008490 name: Ser(Gly)-tRNA(Ala) hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala)." [GOC:jl, PMID:14663147] subset: gosubset_prok synonym: "Ser(Gly)-tRNAAla hydrolase activity" EXACT [] xref: EC:3.1.1.- xref: GO:0043908 xref: IMG:02670 is_a: CCO:F0000566 ! carboxylesterase activity [Term] id: CCO:F0008491 name: N-acetylcitrulline deacetylase activity namespace: molecular_function def: "Catalysis of the reaction: N-acetyl-L-citrulline + H2O => citrulline + acetate." [GOC:jl, IMG:02799, PMID:16750290] subset: gosubset_prok synonym: "acetylcitrulline deacetylase activity" EXACT [] synonym: "N-acetyl-L-citrulline deacetylase activity" EXACT [] xref: EC:3.5.1.- xref: GO:0043909 xref: IMG:02799 is_a: CCO:F0003380 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [Term] id: CCO:F0008492 name: coenzyme F390 synthetase activity namespace: molecular_function def: "Catalysis of the reaction: coenzyme F420 + ATP = coenzyme F390." [GOC:jl, IMG:02803, PMID:7957247, PMID:8550473] subset: gosubset_prok synonym: "ATP:coenzyme F420 adenyltransferase activity" EXACT [] xref: EC:2.7.7.- xref: GO:0043910 xref: IMG:02803 is_a: CCO:F0003351 ! nucleotidyltransferase activity [Term] id: CCO:F0008493 name: D-lysine transaminase activity namespace: molecular_function def: "Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate." [GOC:jl, IMG:02956, PMID:17259313] subset: gosubset_prok synonym: "D-lysine aminotransferase activity" EXACT [] xref: EC:2.6.1.- xref: GO:0043911 xref: IMG:02956 is_a: CCO:F0001944 ! transaminase activity [Term] id: CCO:F0008494 name: D-lysine oxidase activity namespace: molecular_function def: "Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + H2O2." [GOC:jl, IMG:02957, PMID:17259313] subset: gosubset_prok xref: EC:1.4.3.- xref: GO:0043912 xref: IMG:02957 is_a: CCO:F0003241 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor [Term] id: CCO:F0008495 name: NADPH:sulfur oxidoreductase activity namespace: molecular_function def: "Catalysis of the reaction: NADPH + S0 = H2S + NADP." [GOC:jl, PMID:17449625] subset: gosubset_prok synonym: "CoA-dependent NAD(P)H sulfur oxidoreductase activity" EXACT [] synonym: "coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity" EXACT [] synonym: "NAD(P)H elemental sulfur oxidoreductase activity" EXACT [] synonym: "NAD(P)H sulfur oxidoreductase activity" EXACT [] synonym: "NAD(P)H sulphur oxidoreductase activity" EXACT [] synonym: "NAD(P)H:sulfur oxidoreductase activity" EXACT [] synonym: "NADPH:sulphur oxidoreductase activity" EXACT [] synonym: "NSR" EXACT [] xref: EC:1.-.-.- xref: GO:0043914 xref: IMG:03008 is_a: CCO:F0003172 ! oxidoreductase activity [Term] id: CCO:F0008496 name: L-seryl-tRNA(Sec) kinase activity namespace: molecular_function def: "Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec)." [GOC:jl, IMG:03019, UniProt:Q8IV42] subset: gosubset_prok synonym: "O-phosphoseryl-tRNA(Sec) kinase activity" EXACT [] xref: EC:2.7.1.- xref: GO:0043915 xref: IMG:03019 is_a: CCO:F0003345 ! phosphotransferase activity, alcohol group as acceptor [Term] id: CCO:F0008497 name: DNA-7-methylguanine glycosylase activity namespace: molecular_function def: "Catalysis of the hydrolysis of alkylated DNA; recognizes and removes the alkylated base 7-methylguanine." [GOC:jl, PMID:16468998] subset: gosubset_prok xref: EC:3.2.2.- xref: GO:0043916 xref: IMG:03021 is_a: CCO:F0000410 ! alkylbase DNA N-glycosylase activity [Term] id: CCO:F0008498 name: ribose 1,5-bisphosphate isomerase activity namespace: molecular_function def: "Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate." [GOC:jl, IMG:03024] subset: gosubset_prok synonym: "ribose-1,5-bisphosphate isomerase activity" EXACT [] xref: EC:5.3.1.- xref: GO:0043917 xref: IMG:03024 is_a: CCO:F0003423 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses [Term] id: CCO:F0008499 name: cadaverine aminopropyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine." [GOC:jl, IMG:00522, PMID:17545282] subset: gosubset_prok synonym: "cadaverine aminopropyl transferase activity" EXACT [] xref: EC:2.5.1.- xref: GO:0043918 xref: IMG:00522 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0008500 name: agmatine aminopropyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine." [GOC:jl, IMG:03077, PMID:15983049] subset: gosubset_prok synonym: "agmatine aminopropyl transferase activity" EXACT [] xref: EC:2.5.1.- xref: GO:0043919 xref: IMG:03077 is_a: CCO:F0003339 ! transferase activity, transferring alkyl or aryl (other than methyl) groups [Term] id: CCO:F0008501 name: aminopropylagmatine ureohydrolase activity namespace: molecular_function def: "Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea." [GOC:jl, IMG:03079, PMID:15983049] subset: gosubset_prok xref: EC:3.5.3.- xref: GO:0043920 xref: IMG:03079 is_a: CCO:F0003382 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines [Term] id: CCO:F0008502 name: suramin binding namespace: molecular_function def: "Interacting selectively with suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms." [CHEBI:45906, GOC:jl, http://en.wikipedia.org/wiki/Suramin] synonym: "Germanin binding" EXACT [] xref: GO:0043924 is_a: CCO:F0001633 ! binding [Term] id: CCO:F0008503 name: lysozyme inhibitor activity namespace: molecular_function def: "Stops, prevents or reduces the activity of a lysozyme, an enzyme that hydrolyses the beta- (1,4) glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan." [GOC:dph] xref: GO:0060241 is_a: CCO:F0001213 ! enzyme inhibitor activity [Term] id: CCO:F0008504 name: UDP-glucose:4-aminobenzoate acylglucosyltransferase activity namespace: molecular_function def: "Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP." [EC:2.4.1.-, PMID:18385129] synonym: "UDP-glucose:p-aminobenzoate acylglucosyltransferase activity" RELATED [] synonym: "UDP-glucose:p-aminobenzoate glucosyltransferase activity" RELATED [] synonym: "UDP-glucose:pABA acylglucosyltransferase activity" RELATED [] xref: GO:0080002 is_a: CCO:F0005580 ! UDP-glucosyltransferase activity [Term] id: CCO:F0008505 name: thalian-diol desaturase activity namespace: molecular_function def: "Catalysis of the introduction of a double bond to a thalian-diol molecule at carbon 15." [PMID:18356490] xref: GO:0080004 is_a: CCO:F0003228 ! oxidoreductase activity, acting on the CH-CH group of donors [Term] id: CCO:G0003992 name: YWHAB_human def: "14-3-3 protein beta/alpha gene" [UniProtKB:P31946] xref: EMBL:AL008725 xref: EMBL:BC001359 xref: EMBL:X57346 xref: HGNC:HGNC:12849 xref: UniGene:Hs.651212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005480 ! 1433B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0003993 name: YWHAE_human def: "14-3-3 protein epsilon gene" [UniProtKB:P62258] xref: EMBL:AB017103 xref: EMBL:BC000179 xref: EMBL:BC001440 xref: EMBL:BT007161 xref: EMBL:CH471108 xref: EMBL:U20972 xref: EMBL:U28936 xref: EMBL:U43399 xref: EMBL:U43430 xref: EMBL:U54778 xref: HGNC:HGNC:12851 xref: UniGene:Hs.513851 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005488 ! 1433E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0003994 name: YWHAH_human def: "14-3-3 protein eta gene" [UniProtKB:Q04917] synonym: "YWHA1" EXACT [UniProtKB:Q04917] xref: EMBL:BC003047 xref: EMBL:CR456612 xref: EMBL:D78577 xref: EMBL:L20422 xref: EMBL:S80794 xref: EMBL:X57345 xref: EMBL:X78138 xref: EMBL:X80536 xref: EMBL:Z82248 xref: HGNC:HGNC:12853 xref: UniGene:Hs.226755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005490 ! 1433F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0003995 name: YWHAG_human def: "14-3-3 protein gamma gene" [UniProtKB:P61981] xref: EMBL:AB024334 xref: EMBL:AC006388 xref: EMBL:AF142498 xref: EMBL:BC020963 xref: EMBL:CR541904 xref: EMBL:CR541925 xref: HGNC:HGNC:12852 xref: UniGene:Hs.520974 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005489 ! 1433G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0003996 name: SFN_human def: "14-3-3 protein sigma gene" [UniProtKB:P31947] synonym: "HME1" EXACT [UniProtKB:P31947] xref: EMBL:AF029081 xref: EMBL:AF029082 xref: EMBL:AL034380 xref: EMBL:BC000329 xref: EMBL:BC000995 xref: EMBL:BC001550 xref: EMBL:BC002995 xref: EMBL:BC023552 xref: EMBL:CR541905 xref: EMBL:CR541926 xref: EMBL:M93010 xref: EMBL:X57348 xref: HGNC:HGNC:10773 xref: UniGene:Hs.523718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001584 ! 1433S_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0003997 name: YWHAQ_human def: "14-3-3 protein theta gene" [UniProtKB:P27348] xref: EMBL:AF070556 xref: EMBL:BC001197 xref: EMBL:BC050601 xref: EMBL:BC056867 xref: EMBL:BC093019 xref: EMBL:BT020014 xref: EMBL:X56468 xref: EMBL:X57347 xref: HGNC:HGNC:12854 xref: UniGene:Hs.74405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001559 ! 1433T_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0003998 name: YWHAZ_human def: "14-3-3 protein zeta/delta gene" [UniProtKB:P63104] xref: EMBL:BC003623 xref: EMBL:BC051814 xref: EMBL:BC063824 xref: EMBL:BC068456 xref: EMBL:BC072426 xref: EMBL:BC073141 xref: EMBL:BC083508 xref: EMBL:BC099904 xref: EMBL:BC101483 xref: EMBL:BC108281 xref: EMBL:BC111951 xref: EMBL:M86400 xref: EMBL:U28964 xref: HGNC:HGNC:12855 xref: UniGene:Hs.492407 xref: UniGene:Hs.594673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005413 ! 1433Z_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0003999 name: PPP2R5A_human def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform gene" [UniProtKB:Q15172] xref: EMBL:AL360091 xref: EMBL:AL451060 xref: EMBL:BC022474 xref: EMBL:BC110883 xref: EMBL:L42373 xref: HGNC:HGNC:9309 xref: UniGene:Hs.497684 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005516 ! 2A5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004000 name: PPP2R5D_human def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform gene" [UniProtKB:Q14738] xref: EMBL:AB000634 xref: EMBL:AB000635 xref: EMBL:AL136304 xref: EMBL:BC001095 xref: EMBL:BC001175 xref: EMBL:BC010692 xref: EMBL:CH471081 xref: EMBL:D78360 xref: EMBL:L76702 xref: HGNC:HGNC:9312 xref: UniGene:Hs.533308 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005515 ! 2A5D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004001 name: PPP2R5E_human def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform gene" [UniProtKB:Q16537] xref: EMBL:BC093766 xref: EMBL:L76703 xref: EMBL:Z69029 xref: HGNC:HGNC:9313 xref: UniGene:Hs.334868 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005518 ! 2A5E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004002 name: PPP2R1A_human def: "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform gene" [UniProtKB:P30153] xref: EMBL:BC001537 xref: EMBL:CR450340 xref: EMBL:J02902 xref: EMBL:M31786 xref: HGNC:HGNC:9302 xref: UniGene:Hs.467192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001571 ! 2AAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004003 name: PPP2R1B_human def: "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform gene" [UniProtKB:P30154] xref: EMBL:AF083425 xref: EMBL:AF083426 xref: EMBL:AF083427 xref: EMBL:AF083428 xref: EMBL:AF083429 xref: EMBL:AF083430 xref: EMBL:AF083431 xref: EMBL:AF083432 xref: EMBL:AF083433 xref: EMBL:AF083434 xref: EMBL:AF083435 xref: EMBL:AF083436 xref: EMBL:AF083437 xref: EMBL:AF083438 xref: EMBL:AF083439 xref: EMBL:AF087438 xref: EMBL:AF163473 xref: EMBL:M65254 xref: HGNC:HGNC:9303 xref: UniGene:Hs.584790 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005517 ! 2AAB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004004 name: EIF4ENIF1_human def: "Eukaryotic translation initiation factor 4E transporter gene" [UniProtKB:Q9NRA8] xref: EMBL:AF240775 xref: EMBL:AK025254 xref: EMBL:AK074768 xref: EMBL:AL096701 xref: EMBL:BC032941 xref: EMBL:BC033028 xref: EMBL:CH471095 xref: EMBL:CR456386 xref: HGNC:HGNC:16687 xref: UniGene:Hs.517559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006012 ! 4ET_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004005 name: SLC3A2_human def: "4F2 cell-surface antigen heavy chain gene" [UniProtKB:P08195] synonym: "MDU1" EXACT [UniProtKB:P08195] xref: EMBL:AB018010 xref: EMBL:BC001061 xref: EMBL:BC003000 xref: EMBL:J02769 xref: EMBL:J02939 xref: EMBL:J03569 xref: EMBL:M21898 xref: EMBL:M21899 xref: EMBL:M21900 xref: EMBL:M21901 xref: EMBL:M21902 xref: EMBL:M21903 xref: EMBL:M21904 xref: HGNC:HGNC:11026 xref: UniGene:Hs.502769 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005463 ! 4F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004007 name: APP_human def: "Amyloid beta A4 protein precursor gene" [UniProtKB:P05067] synonym: "A4" EXACT [UniProtKB:P05067] synonym: "AD1" EXACT [UniProtKB:P05067] xref: EMBL:AB066441 xref: EMBL:AF282245 xref: EMBL:AY919674 xref: EMBL:BC004369 xref: EMBL:BC065529 xref: EMBL:CH471079 xref: EMBL:D87675 xref: EMBL:M15532 xref: EMBL:M15533 xref: EMBL:M16765 xref: EMBL:M18734 xref: EMBL:M24546 xref: EMBL:M24547 xref: EMBL:M28373 xref: EMBL:M29269 xref: EMBL:M29270 xref: EMBL:M33112 xref: EMBL:M34862 xref: EMBL:M34863 xref: EMBL:M34864 xref: EMBL:M34865 xref: EMBL:M34866 xref: EMBL:M34867 xref: EMBL:M34868 xref: EMBL:M34869 xref: EMBL:M34870 xref: EMBL:M34871 xref: EMBL:M34872 xref: EMBL:M34873 xref: EMBL:M34874 xref: EMBL:M34875 xref: EMBL:M34876 xref: EMBL:M34877 xref: EMBL:M34878 xref: EMBL:M34879 xref: EMBL:M35675 xref: EMBL:M37895 xref: EMBL:M37896 xref: EMBL:S45136 xref: EMBL:S60317 xref: EMBL:S60721 xref: EMBL:S61380 xref: EMBL:S61383 xref: EMBL:X06981 xref: EMBL:X06982 xref: EMBL:X06989 xref: EMBL:X13466 xref: EMBL:X13467 xref: EMBL:X13468 xref: EMBL:X13469 xref: EMBL:X13470 xref: EMBL:X13471 xref: EMBL:X13472 xref: EMBL:X13473 xref: EMBL:X13474 xref: EMBL:X13475 xref: EMBL:X13476 xref: EMBL:X13477 xref: EMBL:X13478 xref: EMBL:X13479 xref: EMBL:X13487 xref: EMBL:X13488 xref: EMBL:Y00264 xref: HGNC:HGNC:620 xref: UniGene:Hs.434980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005474 ! A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004008 name: PRKAA1_human def: "5'-AMP-activated protein kinase catalytic subunit alpha-1 gene" [UniProtKB:Q13131] synonym: "AMPK1" EXACT [UniProtKB:Q13131] xref: EMBL:AB022017 xref: EMBL:AF100763 xref: EMBL:BC037303 xref: EMBL:BC048980 xref: EMBL:U22456 xref: EMBL:Y12856 xref: HGNC:HGNC:9376 xref: UniGene:Hs.43322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005872 ! AAPK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004009 name: AATF_human def: "Protein AATF gene" [UniProtKB:Q9NY61] synonym: "CHE1" EXACT [UniProtKB:Q9NY61] synonym: "DED" EXACT [UniProtKB:Q9NY61] synonym: "HSPC277" EXACT [UniProtKB:Q9NY61] xref: EMBL:AC003103 xref: EMBL:AF083208 xref: EMBL:AF161395 xref: EMBL:AJ249940 xref: EMBL:BC000591 xref: EMBL:CH471199 xref: HGNC:HGNC:19235 xref: UniGene:Hs.195740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005446 ! AATF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004010 name: APOBEC3G_human def: "DNA dC->dU-editing enzyme APOBEC-3G gene" [UniProtKB:Q9HC16] synonym: "MDS019" EXACT [UniProtKB:Q9HC16] xref: EMBL:AF182420 xref: EMBL:AK022802 xref: EMBL:AL022318 xref: EMBL:AL078641 xref: EMBL:BC024268 xref: EMBL:BC061914 xref: EMBL:CR456472 xref: EMBL:DQ147772 xref: HGNC:HGNC:17357 xref: UniGene:Hs.659991 xref: UniGene:Hs.660143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006255 ! ABC3G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004011 name: ABCD4_human def: "ATP-binding cassette sub-family D member 4 gene" [UniProtKB:O14678] synonym: "PXMP1L" EXACT [UniProtKB:O14678] xref: EMBL:AF009746 xref: EMBL:BC012815 xref: EMBL:BT007412 xref: EMBL:CR457104 xref: EMBL:Y14318 xref: EMBL:Y14319 xref: EMBL:Y14320 xref: EMBL:Y14321 xref: EMBL:Y14322 xref: EMBL:Y14323 xref: HGNC:HGNC:68 xref: UniGene:Hs.94395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006268 ! ABCD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004012 name: ABI1_human def: "Abl interactor 1 gene" [UniProtKB:Q8IZP0] synonym: "SSH3BP1" EXACT [UniProtKB:Q8IZP0] xref: EMBL:AB040151 xref: EMBL:AF001628 xref: EMBL:AF006516 xref: EMBL:AF260262 xref: EMBL:AF540955 xref: EMBL:AJ277065 xref: EMBL:AJ277066 xref: EMBL:AJ277067 xref: EMBL:AJ277068 xref: EMBL:AJ277069 xref: EMBL:AJ277070 xref: EMBL:AJ277071 xref: EMBL:AJ277072 xref: EMBL:AJ277073 xref: EMBL:AJ277074 xref: EMBL:AL139404 xref: EMBL:AL390961 xref: EMBL:BC024254 xref: EMBL:U87166 xref: HGNC:HGNC:11320 xref: UniGene:Hs.508148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005703 ! ABI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004013 name: ABL1_human def: "Proto-oncogene tyrosine-protein kinase ABL1 gene" [UniProtKB:P00519] synonym: "ABL" EXACT [UniProtKB:P00519] synonym: "JTK7" EXACT [UniProtKB:P00519] xref: EMBL:DQ145721 xref: EMBL:M14752 xref: EMBL:S69223 xref: EMBL:U07561 xref: EMBL:U07563 xref: EMBL:X16416 xref: HGNC:HGNC:76 xref: UniGene:Hs.431048 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001461 ! ABL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004014 name: ABL2_human def: "Tyrosine-protein kinase ABL2 gene" [UniProtKB:P42684] synonym: "ABLL" EXACT [UniProtKB:P42684] synonym: "ARG" EXACT [UniProtKB:P42684] xref: EMBL:AL139132 xref: EMBL:AL359179 xref: EMBL:AL512326 xref: EMBL:BC065912 xref: EMBL:BX538317 xref: EMBL:M35296 xref: HGNC:HGNC:77 xref: UniGene:Hs.159472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005685 ! ABL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004015 name: ACD_human def: "Adrenocortical dysplasia protein homolog gene" [UniProtKB:Q96AP0] synonym: "PIP1" EXACT [UniProtKB:Q96AP0] synonym: "PTOP" EXACT [UniProtKB:Q96AP0] xref: EMBL:AK023726 xref: EMBL:AY502940 xref: EMBL:AY971883 xref: EMBL:BC016904 xref: HGNC:HGNC:25070 xref: UniGene:Hs.78019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005504 ! ACD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004016 name: TNK2_human def: "Activated CDC42 kinase 1 gene" [UniProtKB:Q07912] synonym: "ACK1" EXACT [UniProtKB:Q07912] xref: EMBL:AK131539 xref: EMBL:BC008884 xref: EMBL:BC028164 xref: EMBL:L13738 xref: HGNC:HGNC:19297 xref: UniGene:Hs.518513 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005836 ! ACK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004017 name: ACTL6A_human def: "Actin-like protein 6A gene" [UniProtKB:O96019] synonym: "BAF53" EXACT [UniProtKB:O96019] synonym: "BAF53A" EXACT [UniProtKB:O96019] synonym: "INO80K" EXACT [UniProtKB:O96019] xref: EMBL:AB015907 xref: EMBL:AB060168 xref: EMBL:AB061315 xref: EMBL:AF041474 xref: EMBL:AL136608 xref: EMBL:BC000949 xref: EMBL:BC001391 xref: EMBL:BC036371 xref: HGNC:HGNC:24124 xref: UniGene:Hs.435326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005366 ! ACL6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004018 name: ACSS2_human def: "Acetyl-coenzyme A synthetase, cytoplasmic gene" [UniProtKB:Q9NR19] synonym: "ACAS2" EXACT [UniProtKB:Q9NR19] xref: EMBL:AF263614 xref: EMBL:AL049709 xref: EMBL:AL133324 xref: EMBL:BC012172 xref: HGNC:HGNC:15814 xref: UniGene:Hs.517034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005570 ! ACSA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004019 name: ACTA2_human def: "Actin, aortic smooth muscle gene" [UniProtKB:P62736] synonym: "ACTSA" EXACT [UniProtKB:P62736] synonym: "ACTVS" EXACT [UniProtKB:P62736] synonym: "GIG46" EXACT [UniProtKB:P62736] xref: EMBL:AL157394 xref: EMBL:AY692464 xref: EMBL:BC017554 xref: EMBL:BC093052 xref: EMBL:CR536518 xref: EMBL:J05192 xref: EMBL:K01741 xref: EMBL:K01742 xref: EMBL:K01743 xref: EMBL:M33216 xref: EMBL:X13839 xref: HGNC:HGNC:130 xref: UniGene:Hs.500483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005810 ! ACTA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004020 name: ACTB_human def: "Actin, cytoplasmic 1 gene" [UniProtKB:P60709] xref: EMBL:AC006483 xref: EMBL:AY582799 xref: EMBL:BC001301 xref: EMBL:BC002409 xref: EMBL:BC004251 xref: EMBL:BC012854 xref: EMBL:BC013380 xref: EMBL:BC014861 xref: EMBL:BC016045 xref: EMBL:M10277 xref: EMBL:V00478 xref: EMBL:X00351 xref: EMBL:X63432 xref: HGNC:HGNC:132 xref: UniGene:Hs.520640 xref: UniGene:Hs.702191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005775 ! ACTB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004021 name: ACTN1_human def: "Alpha-actinin-1 gene" [UniProtKB:P12814] xref: EMBL:BC003576 xref: EMBL:BC015766 xref: EMBL:BT007207 xref: EMBL:M95178 xref: EMBL:X15804 xref: EMBL:X55187 xref: HGNC:HGNC:163 xref: UniGene:Hs.509765 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005948 ! ACTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004022 name: ACTN2_human def: "Alpha-actinin-2 gene" [UniProtKB:P35609] xref: EMBL:AJ249756 xref: EMBL:AJ249757 xref: EMBL:AJ249758 xref: EMBL:AJ249759 xref: EMBL:AJ249760 xref: EMBL:AJ249761 xref: EMBL:AJ249762 xref: EMBL:AJ249763 xref: EMBL:AJ249764 xref: EMBL:AJ249765 xref: EMBL:AJ249766 xref: EMBL:AJ249767 xref: EMBL:AJ249768 xref: EMBL:AJ249769 xref: EMBL:AJ249770 xref: EMBL:AJ249771 xref: EMBL:AJ249772 xref: EMBL:AJ249773 xref: EMBL:AJ249774 xref: EMBL:AJ249775 xref: EMBL:AJ249776 xref: EMBL:BC047901 xref: EMBL:BC051770 xref: EMBL:M86406 xref: EMBL:M86804 xref: HGNC:HGNC:164 xref: UniGene:Hs.498178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005642 ! ACTN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004023 name: ACTN4_human def: "Alpha-actinin-4 gene" [UniProtKB:O43707] xref: EMBL:AL047603 xref: EMBL:AU118403 xref: EMBL:BC005033 xref: EMBL:D89980 xref: EMBL:U48734 xref: HGNC:HGNC:166 xref: UniGene:Hs.270291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001397 ! ACTN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004024 name: ACVR1B_human def: "Activin receptor type-1B precursor gene" [UniProtKB:P36896] synonym: "ACVRLK4" EXACT [UniProtKB:P36896] xref: EMBL:BC000254 xref: EMBL:BC040531 xref: EMBL:BT007072 xref: EMBL:L10125 xref: EMBL:L10126 xref: EMBL:L31848 xref: EMBL:U14722 xref: EMBL:Z22536 xref: HGNC:HGNC:172 xref: UniGene:Hs.438918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001597 ! ACV1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004025 name: ACVR1_human def: "Activin receptor type-1 precursor gene" [UniProtKB:Q04771] synonym: "ACVRLK2" EXACT [UniProtKB:Q04771] xref: EMBL:BC033867 xref: EMBL:L02911 xref: EMBL:Z22534 xref: HGNC:HGNC:171 xref: UniGene:Hs.470316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001720 ! ACVR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004026 name: ADAM15_human def: "ADAM 15 precursor gene" [UniProtKB:Q13444] synonym: "MDC15" EXACT [UniProtKB:Q13444] xref: EMBL:AF314227 xref: EMBL:AY560594 xref: EMBL:BC014566 xref: EMBL:BT009764 xref: EMBL:U41767 xref: EMBL:U46005 xref: HGNC:HGNC:193 xref: UniGene:Hs.312098 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005909 ! ADA15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004027 name: ADAM17_human def: "ADAM 17 precursor gene" [UniProtKB:P78536] synonym: "CSVP" EXACT [UniProtKB:P78536] synonym: "TACE" EXACT [UniProtKB:P78536] xref: EMBL:U69611 xref: EMBL:U69612 xref: EMBL:U86755 xref: EMBL:U92649 xref: HGNC:HGNC:195 xref: UniGene:Hs.404914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005712 ! ADA17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004028 name: TADA2L_human def: "Transcriptional adapter 2-alpha gene" [UniProtKB:O75478] synonym: "KL04P" EXACT [UniProtKB:O75478] xref: EMBL:AC004099 xref: EMBL:AC068400 xref: EMBL:AC068447 xref: EMBL:AF064094 xref: EMBL:AF069732 xref: EMBL:BC001172 xref: EMBL:BC011753 xref: HGNC:HGNC:11531 xref: UniGene:Hs.500066 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005318 ! Q9BVJ0_HUMAN relationship: codes_for CCO:B0048883 ! TAD2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004029 name: ADAM9_human def: "ADAM 9 precursor gene" [UniProtKB:Q13443] synonym: "KIAA0021" EXACT [UniProtKB:Q13443] synonym: "MCMP" EXACT [UniProtKB:Q13443] synonym: "MDC9" EXACT [UniProtKB:Q13443] synonym: "MLTNG" EXACT [UniProtKB:Q13443] xref: EMBL:AF495383 xref: EMBL:D14665 xref: EMBL:U41766 xref: HGNC:HGNC:216 xref: UniGene:Hs.591852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005372 ! ADAM9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004030 name: ADCY3_human def: "Adenylate cyclase type 3 gene" [UniProtKB:O60266] synonym: "KIAA0511" EXACT [UniProtKB:O60266] xref: EMBL:AB011083 xref: EMBL:AC012073 xref: EMBL:AF033861 xref: EMBL:BC126235 xref: HGNC:HGNC:234 xref: UniGene:Hs.705457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001406 ! ADCY3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004031 name: ADPGK_human def: "ADP-dependent glucokinase precursor gene" [UniProtKB:Q9BRR6] synonym: "PSEC0260" EXACT [UniProtKB:Q9BRR6] xref: EMBL:AF204270 xref: EMBL:AK055526 xref: EMBL:AK075560 xref: EMBL:AL136873 xref: EMBL:BC006112 xref: EMBL:BC018074 xref: EMBL:CR533447 xref: HGNC:HGNC:25250 xref: UniGene:Hs.654636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006354 ! ADPGK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004032 name: SLC25A5_human def: "ADP/ATP translocase 2 gene" [UniProtKB:P05141] synonym: "ANT2" EXACT [UniProtKB:P05141] xref: EMBL:AC004000 xref: EMBL:BC056160 xref: EMBL:J02683 xref: EMBL:J03591 xref: EMBL:L78810 xref: EMBL:M57424 xref: HGNC:HGNC:10991 xref: UniGene:Hs.644618 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005813 ! ADT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004033 name: AES_human def: "Amino-terminal enhancer of split gene" [UniProtKB:Q08117] synonym: "GRG" EXACT [UniProtKB:Q08117] xref: EMBL:AC005944 xref: EMBL:AF072902 xref: EMBL:U04241 xref: EMBL:U88831 xref: EMBL:U88832 xref: EMBL:X73358 xref: HGNC:HGNC:307 xref: UniGene:Hs.515053 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005987 ! AES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004034 name: AFAP1L2_human def: "Actin filament-associated protein 1-like 2 gene" [UniProtKB:Q8N4X5] synonym: "KIAA1914" EXACT [UniProtKB:Q8N4X5] xref: EMBL:AB067501 xref: EMBL:AC005383 xref: EMBL:AK027470 xref: EMBL:AL133384 xref: EMBL:AL355302 xref: EMBL:BC024314 xref: EMBL:BC033212 xref: HGNC:HGNC:25901 xref: UniGene:Hs.501106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001964 ! AF1L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004035 name: MLLT3_human def: "Protein AF-9 gene" [UniProtKB:P42568] synonym: "AF9" EXACT [UniProtKB:P42568] synonym: "YEATS3" EXACT [UniProtKB:P42568] xref: EMBL:AL354879 xref: EMBL:AL512635 xref: EMBL:AL513498 xref: EMBL:BC036089 xref: EMBL:CH471071 xref: EMBL:L13744 xref: HGNC:HGNC:7136 xref: UniGene:Hs.591085 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005303 ! Q8IVB0_HUMAN relationship: codes_for CCO:B0006206 ! AF9_HUMAN relationship: codes_for CCO:B0054274 ! B1APT5_HUMAN relationship: codes_for CCO:B0054275 ! B1APT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004036 name: MLLT4_human def: "Afadin gene" [UniProtKB:P55196] synonym: "AF6" EXACT [UniProtKB:P55196] xref: EMBL:AB011399 xref: EMBL:AL009178 xref: EMBL:AL049698 xref: EMBL:AL161973 xref: EMBL:AL731868 xref: EMBL:BC014505 xref: EMBL:CH471051 xref: EMBL:U02478 xref: HGNC:HGNC:7137 xref: UniGene:Hs.614974 xref: UniGene:Hs.644024 xref: UniGene:Hs.701126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005914 ! AFAD_HUMAN relationship: codes_for CCO:B0054015 ! A8MSW6_HUMAN relationship: codes_for CCO:B0056629 ! Q5TIG5_HUMAN relationship: codes_for CCO:B0056630 ! Q5TIG7_HUMAN relationship: codes_for CCO:B0056631 ! Q5TIH0_HUMAN relationship: codes_for CCO:B0056632 ! Q5TIH1_HUMAN relationship: codes_for CCO:B0058180 ! Q96C95_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004038 name: AHR_human def: "Aryl hydrocarbon receptor precursor gene" [UniProtKB:P35869] xref: EMBL:AC003075 xref: EMBL:BC069390 xref: EMBL:BC070080 xref: EMBL:D16354 xref: EMBL:D38044 xref: EMBL:L19872 xref: EMBL:U27656 xref: EMBL:U27657 xref: EMBL:U28060 xref: EMBL:U28061 xref: EMBL:U28062 xref: EMBL:U28063 xref: EMBL:U28064 xref: EMBL:U28065 xref: EMBL:U28066 xref: HGNC:HGNC:348 xref: UniGene:Hs.171189 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001595 ! AHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004039 name: AIF1_human def: "Allograft inflammatory factor 1 gene" [UniProtKB:P55008] synonym: "G1" EXACT [UniProtKB:P55008] synonym: "IBA1" EXACT [UniProtKB:P55008] xref: EMBL:AF129756 xref: EMBL:AL662801 xref: EMBL:AL662847 xref: EMBL:AL805934 xref: EMBL:BA000025 xref: EMBL:BC009474 xref: EMBL:D86438 xref: EMBL:U19713 xref: EMBL:U49392 xref: EMBL:Y14768 xref: HGNC:HGNC:352 xref: UniGene:Hs.76364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001673 ! AIF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004040 name: AIP_human def: "AH receptor-interacting protein gene" [UniProtKB:O00170] synonym: "XAP2" EXACT [UniProtKB:O00170] xref: EMBL:AM236341 xref: EMBL:BC104797 xref: EMBL:BC104827 xref: EMBL:U31913 xref: EMBL:U78521 xref: HGNC:HGNC:358 xref: UniGene:Hs.412433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005380 ! AIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004041 name: AKR1C3_human def: "Aldo-keto reductase family 1 member C3 gene" [UniProtKB:P42330] synonym: "DDH1" EXACT [UniProtKB:P42330] synonym: "HSD17B5" EXACT [UniProtKB:P42330] synonym: "KIAA0119" EXACT [UniProtKB:P42330] synonym: "PGFS" EXACT [UniProtKB:P42330] xref: EMBL:AB018580 xref: EMBL:AB028065 xref: EMBL:AB032157 xref: EMBL:AF149416 xref: EMBL:AL391427 xref: EMBL:BC001479 xref: EMBL:BC019230 xref: EMBL:BT007286 xref: EMBL:D17793 xref: EMBL:L43831 xref: EMBL:L43832 xref: EMBL:L43833 xref: EMBL:L43834 xref: EMBL:L43835 xref: EMBL:L43836 xref: EMBL:L43837 xref: EMBL:L43838 xref: EMBL:L43839 xref: EMBL:S68288 xref: HGNC:HGNC:386 xref: UniGene:Hs.78183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006117 ! AK1C3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004042 name: AKAP8_human def: "A-kinase anchor protein 8 gene" [UniProtKB:O43823] synonym: "AKAP95" EXACT [UniProtKB:O43823] xref: EMBL:AC005785 xref: EMBL:Y11997 xref: HGNC:HGNC:378 xref: UniGene:Hs.631640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001399 ! AKAP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004043 name: AKAP9_human def: "A-kinase anchor protein 9 gene" [UniProtKB:Q99996] synonym: "AKAP350" EXACT [UniProtKB:Q99996] synonym: "AKAP450" EXACT [UniProtKB:Q99996] synonym: "KIAA0803" EXACT [UniProtKB:Q99996] xref: EMBL:AB018346 xref: EMBL:AB019691 xref: EMBL:AC000066 xref: EMBL:AC000120 xref: EMBL:AC004013 xref: EMBL:AF026245 xref: EMBL:AF083037 xref: EMBL:AF091711 xref: EMBL:AJ010770 xref: EMBL:AJ131693 xref: HGNC:HGNC:379 xref: UniGene:Hs.651221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005588 ! AKAP9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004044 name: AURKAIP1_human def: "Aurora kinase A-interacting protein gene" [UniProtKB:Q9NWT8] synonym: "AIP" EXACT [UniProtKB:Q9NWT8] synonym: "AKIP" EXACT [UniProtKB:Q9NWT8] xref: EMBL:AK000615 xref: EMBL:AL139287 xref: EMBL:BC022808 xref: EMBL:BC062333 xref: HGNC:HGNC:24114 xref: UniGene:Hs.515704 xref: UniGene:Hs.632515 xref: UniGene:Hs.658138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002171 ! AKIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004045 name: AKT1_human def: "RAC-alpha serine/threonine-protein kinase gene" [UniProtKB:P31749] synonym: "PKB" EXACT [UniProtKB:P31749] synonym: "RAC" EXACT [UniProtKB:P31749] xref: EMBL:AF283819 xref: EMBL:AF283820 xref: EMBL:AF283821 xref: EMBL:AF283822 xref: EMBL:AF283823 xref: EMBL:AF283824 xref: EMBL:AF283825 xref: EMBL:AF283826 xref: EMBL:AF283827 xref: EMBL:AF283828 xref: EMBL:AF283829 xref: EMBL:AF283830 xref: EMBL:BC000479 xref: EMBL:BC084538 xref: EMBL:M63167 xref: EMBL:X61037 xref: HGNC:HGNC:391 xref: UniGene:Hs.525622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005512 ! AKT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004046 name: AKT2_human def: "RAC-beta serine/threonine-protein kinase gene" [UniProtKB:P31751] xref: EMBL:AY708392 xref: EMBL:BC120994 xref: EMBL:M77198 xref: EMBL:M95936 xref: HGNC:HGNC:392 xref: UniGene:Hs.631535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005910 ! AKT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004047 name: AKT3_human def: "RAC-gamma serine/threonine-protein kinase gene" [UniProtKB:Q9Y243] synonym: "PKBG" EXACT [UniProtKB:Q9Y243] xref: EMBL:AC096539 xref: EMBL:AF085234 xref: EMBL:AF124141 xref: EMBL:AF135794 xref: EMBL:AJ245709 xref: EMBL:AL117525 xref: EMBL:AL591721 xref: EMBL:AL592151 xref: EMBL:AL662889 xref: EMBL:AY005799 xref: EMBL:BC121154 xref: EMBL:CH471148 xref: HGNC:HGNC:393 xref: UniGene:Hs.498292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005911 ! AKT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004049 name: ALK_human def: "ALK tyrosine kinase receptor precursor gene" [UniProtKB:Q9UM73] xref: EMBL:AB209477 xref: EMBL:AC074096 xref: EMBL:AC093756 xref: EMBL:AC106870 xref: EMBL:U62540 xref: EMBL:U66559 xref: HGNC:HGNC:427 xref: UniGene:Hs.654469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005628 ! ALK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004050 name: AMOTL2_human def: "Angiomotin-like protein 2 gene" [UniProtKB:Q9Y2J4] synonym: "KIAA0989" EXACT [UniProtKB:Q9Y2J4] xref: EMBL:AB023206 xref: EMBL:AF175966 xref: EMBL:AK223598 xref: EMBL:BC011454 xref: HGNC:HGNC:17812 xref: UniGene:Hs.426312 xref: UniGene:Hs.705466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005299 ! AMOL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004051 name: LRPAP1_human def: "Alpha-2-macroglobulin receptor-associated protein precursor gene" [UniProtKB:P30533] synonym: "A2MRAP" EXACT [UniProtKB:P30533] xref: EMBL:AF035760 xref: EMBL:AF035761 xref: EMBL:AF035762 xref: EMBL:AF035763 xref: EMBL:AF035764 xref: EMBL:AF035765 xref: EMBL:AF035766 xref: EMBL:AF035767 xref: EMBL:AK222504 xref: EMBL:AK222527 xref: EMBL:AL590235 xref: EMBL:BC105074 xref: EMBL:BC112067 xref: EMBL:M63959 xref: EMBL:U06976 xref: HGNC:HGNC:6701 xref: UniGene:Hs.533136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006334 ! AMRP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004052 name: ANP32A_human def: "Acidic leucine-rich nuclear phosphoprotein 32 family member A gene" [UniProtKB:P39687] synonym: "C15orf1" EXACT [UniProtKB:P39687] synonym: "LANP" EXACT [UniProtKB:P39687] synonym: "MAPM" EXACT [UniProtKB:P39687] synonym: "PHAP1" EXACT [UniProtKB:P39687] xref: EMBL:AF025684 xref: EMBL:AK223280 xref: EMBL:AY349171 xref: EMBL:BC007200 xref: EMBL:BT007436 xref: EMBL:CH471082 xref: EMBL:U60823 xref: EMBL:U73477 xref: EMBL:X75090 xref: HGNC:HGNC:13233 xref: UniGene:Hs.458747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006073 ! AN32A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004053 name: ANAPC13_human def: "Anaphase-promoting complex subunit 13 gene" [UniProtKB:Q9BS18] xref: EMBL:AL050051 xref: EMBL:BC005398 xref: HGNC:HGNC:24540 xref: UniGene:Hs.106909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002095 ! APC13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004054 name: ANAPC1_human def: "Anaphase-promoting complex subunit 1 gene" [UniProtKB:Q9H1A4] synonym: "TSG24" EXACT [UniProtKB:Q9H1A4] xref: EMBL:AJ278357 xref: EMBL:AK023807 xref: EMBL:BC005089 xref: EMBL:BC104902 xref: EMBL:BC104904 xref: HGNC:HGNC:19988 xref: UniGene:Hs.436527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002125 ! APC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004055 name: ANAPC2_human def: "Anaphase-promoting complex subunit 2 gene" [UniProtKB:Q9UJX6] synonym: "APC2" EXACT [UniProtKB:Q9UJX6] synonym: "KIAA1406" EXACT [UniProtKB:Q9UJX6] xref: EMBL:AB037827 xref: EMBL:AF191337 xref: EMBL:AL929554 xref: EMBL:BC001579 xref: EMBL:BC009487 xref: EMBL:BC032503 xref: HGNC:HGNC:19989 xref: UniGene:Hs.533262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002216 ! ANC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004056 name: ANAPC4_human def: "Anaphase-promoting complex subunit 4 gene" [UniProtKB:Q9UJX5] synonym: "APC4" EXACT [UniProtKB:Q9UJX5] xref: EMBL:AF191338 xref: EMBL:AK292336 xref: EMBL:AL353932 xref: EMBL:BC059383 xref: EMBL:CH471069 xref: HGNC:HGNC:19990 xref: UniGene:Hs.152173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002215 ! APC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004057 name: ANAPC5_human def: "Anaphase-promoting complex subunit 5 gene" [UniProtKB:Q9UJX4] synonym: "APC5" EXACT [UniProtKB:Q9UJX4] xref: EMBL:AF191339 xref: EMBL:BC001081 xref: EMBL:BC001950 xref: EMBL:BC006301 xref: EMBL:BC034243 xref: EMBL:BX537687 xref: HGNC:HGNC:15713 xref: UniGene:Hs.7101 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002214 ! APC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004058 name: AR_human def: "Androgen receptor gene" [UniProtKB:P10275] synonym: "DHTR" EXACT [UniProtKB:P10275] synonym: "NR3C4" EXACT [UniProtKB:P10275] xref: EMBL:AL049564 xref: EMBL:AL158016 xref: EMBL:AL356358 xref: EMBL:BC132975 xref: EMBL:CH471132 xref: EMBL:L29496 xref: EMBL:M20132 xref: EMBL:M20260 xref: EMBL:M21748 xref: EMBL:M23263 xref: EMBL:M27423 xref: EMBL:M27424 xref: EMBL:M27425 xref: EMBL:M27426 xref: EMBL:M27427 xref: EMBL:M27428 xref: EMBL:M27429 xref: EMBL:M27430 xref: EMBL:M34233 xref: EMBL:M35844 xref: EMBL:M35845 xref: EMBL:M35846 xref: EMBL:M35847 xref: EMBL:M35848 xref: EMBL:M35849 xref: EMBL:M35850 xref: EMBL:M35851 xref: EMBL:S79366 xref: EMBL:U16371 xref: HGNC:HGNC:644 xref: UniGene:Hs.496240 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005356 ! ANDR_HUMAN relationship: codes_for CCO:B0054226 ! B1AKD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004059 name: ANG_human def: "Angiogenin precursor gene" [UniProtKB:P03950] synonym: "RNASE5" EXACT [UniProtKB:P03950] xref: EMBL:AF449647 xref: EMBL:AF449648 xref: EMBL:AF449649 xref: EMBL:AF449650 xref: EMBL:AF449651 xref: EMBL:BC054880 xref: EMBL:M11567 xref: HGNC:HGNC:483 xref: UniGene:Hs.283749 xref: UniGene:Hs.706192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006220 ! ANGI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004060 name: ANKS3_human def: "Ankyrin repeat and SAM domain-containing protein 3 gene" [UniProtKB:Q6ZW76] synonym: "KIAA1977" EXACT [UniProtKB:Q6ZW76] xref: EMBL:AB075857 xref: EMBL:AK123496 xref: HGNC:HGNC:29422 xref: UniGene:Hs.654859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005965 ! ANKS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004061 name: ANKZF1_human def: "Ankyrin repeat and zinc finger domain-containing protein 1 gene" [UniProtKB:Q9H8Y5] synonym: "ZNF744" EXACT [UniProtKB:Q9H8Y5] xref: EMBL:AK001277 xref: EMBL:AK023206 xref: EMBL:BC000238 xref: EMBL:BC008948 xref: EMBL:DQ412564 xref: HGNC:HGNC:25527 xref: UniGene:Hs.437647 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006329 ! ANKZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004062 name: ANLN_human def: "Actin-binding protein anillin gene" [UniProtKB:Q9NQW6] xref: EMBL:AF273437 xref: EMBL:AK001468 xref: EMBL:AK001472 xref: EMBL:AK023208 xref: EMBL:BC034692 xref: EMBL:BC070066 xref: EMBL:CR936650 xref: HGNC:HGNC:14082 xref: UniGene:Hs.62180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002155 ! ANLN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004063 name: PRMT1_human def: "Protein arginine N-methyltransferase 1 gene" [UniProtKB:Q99873] synonym: "HMT2" EXACT [UniProtKB:Q99873] synonym: "HRMT1L2" EXACT [UniProtKB:Q99873] synonym: "IR1B4" EXACT [UniProtKB:Q99873] xref: EMBL:AF222689 xref: EMBL:D66904 xref: EMBL:Y10805 xref: EMBL:Y10806 xref: EMBL:Y10807 xref: HGNC:HGNC:5187 xref: UniGene:Hs.20521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005713 ! ANM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004064 name: PRMT2_human def: "Protein arginine N-methyltransferase 2 gene" [UniProtKB:P55345] synonym: "HMT1" EXACT [UniProtKB:P55345] synonym: "HRMT1L1" EXACT [UniProtKB:P55345] xref: EMBL:AL109794 xref: EMBL:BC000727 xref: EMBL:U80213 xref: EMBL:X99209 xref: HGNC:HGNC:5186 xref: UniGene:Hs.154163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005630 ! ANM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004065 name: PRMT5_human def: "Protein arginine N-methyltransferase 5 gene" [UniProtKB:O14744] synonym: "HRMT1L5" EXACT [UniProtKB:O14744] synonym: "IBP72" EXACT [UniProtKB:O14744] synonym: "JBP1" EXACT [UniProtKB:O14744] synonym: "SKB1" EXACT [UniProtKB:O14744] xref: EMBL:AF015913 xref: EMBL:AF167572 xref: EMBL:BC025979 xref: EMBL:CR456741 xref: HGNC:HGNC:10894 xref: UniGene:Hs.367854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001357 ! ANM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004067 name: SERPINC1_human def: "Antithrombin-III precursor gene" [UniProtKB:P01008] synonym: "AT3" EXACT [UniProtKB:P01008] synonym: "PRO0309" EXACT [UniProtKB:P01008] xref: EMBL:AF130100 xref: EMBL:AF386078 xref: EMBL:L00185 xref: EMBL:L00186 xref: EMBL:L00190 xref: EMBL:M21636 xref: EMBL:M21637 xref: EMBL:M21638 xref: EMBL:M21640 xref: EMBL:M21641 xref: EMBL:M21642 xref: EMBL:M21643 xref: EMBL:M21644 xref: EMBL:X68793 xref: HGNC:HGNC:775 xref: UniGene:Hs.75599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005871 ! ANT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004068 name: ANXA1_human def: "Annexin A1 gene" [UniProtKB:P04083] synonym: "ANX1" EXACT [UniProtKB:P04083] synonym: "LPC1" EXACT [UniProtKB:P04083] xref: EMBL:BC001275 xref: EMBL:BC035993 xref: EMBL:X05908 xref: HGNC:HGNC:533 xref: UniGene:Hs.494173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001479 ! ANXA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004069 name: ANXA2_human def: "Annexin A2 gene" [UniProtKB:P07355] synonym: "ANX2" EXACT [UniProtKB:P07355] synonym: "ANX2L4" EXACT [UniProtKB:P07355] synonym: "CAL1H" EXACT [UniProtKB:P07355] synonym: "LPC2D" EXACT [UniProtKB:P07355] xref: EMBL:BC001388 xref: EMBL:BC009564 xref: EMBL:BC015834 xref: EMBL:BC016774 xref: EMBL:BC021114 xref: EMBL:BC052558 xref: EMBL:BC052567 xref: EMBL:BC066955 xref: EMBL:BC068065 xref: EMBL:BC093056 xref: EMBL:BT007432 xref: EMBL:D00017 xref: HGNC:HGNC:537 xref: UniGene:Hs.511605 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005736 ! ANXA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004070 name: ANXA3_human def: "Annexin A3 gene" [UniProtKB:P12429] synonym: "ANX3" EXACT [UniProtKB:P12429] xref: EMBL:BC000871 xref: EMBL:CR407648 xref: EMBL:L20591 xref: EMBL:M20560 xref: EMBL:M63310 xref: HGNC:HGNC:541 xref: UniGene:Hs.480042 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006119 ! ANXA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004071 name: ANXA6_human def: "Annexin A6 gene" [UniProtKB:P08133] synonym: "ANX6" EXACT [UniProtKB:P08133] xref: EMBL:AK126836 xref: EMBL:BC017046 xref: EMBL:D00510 xref: EMBL:J03578 xref: EMBL:Y00097 xref: HGNC:HGNC:544 xref: UniGene:Hs.412117 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005731 ! ANXA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004072 name: TFAP2A_human def: "Transcription factor AP-2 alpha gene" [UniProtKB:P05549] synonym: "AP2TF" EXACT [UniProtKB:P05549] synonym: "TFAP2" EXACT [UniProtKB:P05549] xref: EMBL:AL138885 xref: EMBL:BC017754 xref: EMBL:CH471087 xref: EMBL:M36711 xref: EMBL:M61156 xref: EMBL:X52611 xref: EMBL:X77343 xref: HGNC:HGNC:11742 xref: UniGene:Hs.519880 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005640 ! AP2A_HUMAN relationship: codes_for CCO:B0038042 ! Q96SH0_HUMAN relationship: codes_for CCO:B0038045 ! Q96SH1_HUMAN relationship: codes_for CCO:B0038046 ! Q8N1C6_HUMAN relationship: codes_for CCO:B0038047 ! Q5TAV5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004073 name: AP2B1_human def: "AP-2 complex subunit beta-1 gene" [UniProtKB:P63010] synonym: "ADTB2" EXACT [UniProtKB:P63010] synonym: "CLAPB1" EXACT [UniProtKB:P63010] xref: EMBL:AC006237 xref: EMBL:BC006201 xref: EMBL:CH471147 xref: EMBL:M34175 xref: HGNC:HGNC:563 xref: UniGene:Hs.514819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005197 ! AP2B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004074 name: TFAP2B_human def: "Transcription factor AP-2 beta gene" [UniProtKB:Q92481] xref: EMBL:AJ278356 xref: EMBL:AL031224 xref: EMBL:AL049693 xref: EMBL:BC037225 xref: EMBL:X95694 xref: EMBL:Y09912 xref: HGNC:HGNC:11743 xref: UniGene:Hs.33102 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005680 ! AP2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004075 name: TFAP2C_human def: "Transcription factor AP-2 gamma gene" [UniProtKB:Q92754] xref: EMBL:AB041717 xref: EMBL:AJ315934 xref: EMBL:AL121920 xref: EMBL:BC035664 xref: EMBL:BC051829 xref: EMBL:U85658 xref: EMBL:X95693 xref: HGNC:HGNC:11744 xref: UniGene:Hs.473152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005377 ! AP2C_HUMAN relationship: codes_for CCO:B0038041 ! A2A2R7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004076 name: APBB1_human def: "Amyloid beta A4 precursor protein-binding family B member 1 gene" [UniProtKB:O00213] synonym: "FE65" EXACT [UniProtKB:O00213] synonym: "RIR" EXACT [UniProtKB:O00213] xref: EMBL:AC068733 xref: EMBL:AF029234 xref: EMBL:AF047835 xref: EMBL:AF394214 xref: EMBL:BC010854 xref: EMBL:CH471064 xref: EMBL:L77864 xref: HGNC:HGNC:581 xref: UniGene:Hs.372840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001344 ! APBB1_HUMAN relationship: codes_for CCO:B0001998 ! Q8TEY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004077 name: APBB2_human def: "Amyloid beta A4 precursor protein-binding family B member 2 gene" [UniProtKB:Q92870] synonym: "FE65L" EXACT [UniProtKB:Q92870] synonym: "FE65L1" EXACT [UniProtKB:Q92870] xref: EMBL:BC027946 xref: EMBL:U62325 xref: HGNC:HGNC:582 xref: UniGene:Hs.479602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002020 ! APBB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004078 name: ANAPC10_human def: "Anaphase-promoting complex subunit 10 gene" [UniProtKB:Q9UM13] synonym: "APC10" EXACT [UniProtKB:Q9UM13] xref: EMBL:AB012109 xref: EMBL:AF132794 xref: EMBL:AL080090 xref: EMBL:BC005217 xref: EMBL:DQ304649 xref: HGNC:HGNC:24077 xref: UniGene:Hs.480876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002230 ! APC10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004079 name: ANAPC11_human def: "Anaphase-promoting complex subunit 11 gene" [UniProtKB:Q9NYG5] synonym: "HSPC214" EXACT [UniProtKB:Q9NYG5] xref: EMBL:AF151048 xref: EMBL:AF247565 xref: EMBL:AF247789 xref: EMBL:BC000607 xref: EMBL:BC066308 xref: EMBL:BC095454 xref: EMBL:BC104641 xref: HGNC:HGNC:14452 xref: UniGene:Hs.534456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002177 ! APC11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004080 name: ANAPC7_human def: "Anaphase-promoting complex subunit 7 gene" [UniProtKB:Q9UJX3] synonym: "APC7" EXACT [UniProtKB:Q9UJX3] xref: EMBL:AF191340 xref: EMBL:AL137586 xref: EMBL:BC002941 xref: EMBL:BC009498 xref: EMBL:BC017316 xref: HGNC:HGNC:17380 xref: UniGene:Hs.529280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002213 ! APC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004081 name: APC_human def: "Adenomatous polyposis coli protein gene" [UniProtKB:P25054] synonym: "DP2.5" EXACT [UniProtKB:P25054] xref: EMBL:M73548 xref: EMBL:M74088 xref: EMBL:S78214 xref: HGNC:HGNC:583 xref: UniGene:Hs.158932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001556 ! APC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004082 name: APLP1_human def: "Amyloid-like protein 1 precursor gene" [UniProtKB:P51693] xref: EMBL:AD000864 xref: EMBL:BC012889 xref: EMBL:U48437 xref: HGNC:HGNC:597 xref: UniGene:Hs.74565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006179 ! APLP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004083 name: APLP2_human def: "Amyloid-like protein 2 precursor gene" [UniProtKB:Q06481] synonym: "APPL2" EXACT [UniProtKB:Q06481] xref: EMBL:AF168956 xref: EMBL:BC000373 xref: EMBL:BC004371 xref: EMBL:L09209 xref: EMBL:L19597 xref: EMBL:L23113 xref: EMBL:L23114 xref: EMBL:L27631 xref: EMBL:S60099 xref: EMBL:Z22572 xref: HGNC:HGNC:598 xref: UniGene:Hs.370247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005374 ! APLP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004085 name: PMAIP1_human def: "Phorbol-12-myristate-13-acetate-induced protein 1 gene" [UniProtKB:Q13794] synonym: "NOXA" EXACT [UniProtKB:Q13794] xref: EMBL:BC013120 xref: EMBL:D90070 xref: HGNC:HGNC:9108 xref: UniGene:Hs.96 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006340 ! APR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004086 name: APTX_human def: "Aprataxin gene" [UniProtKB:Q7Z2E3] synonym: "AXA1" EXACT [UniProtKB:Q7Z2E3] xref: EMBL:AJ565850 xref: EMBL:AJ565851 xref: EMBL:AJ565852 xref: EMBL:AJ565853 xref: EMBL:AJ565854 xref: EMBL:AJ565855 xref: EMBL:AJ575566 xref: EMBL:AK000164 xref: EMBL:AL353717 xref: EMBL:AY040777 xref: EMBL:AY208829 xref: EMBL:AY208830 xref: EMBL:AY208831 xref: EMBL:AY208832 xref: EMBL:AY208833 xref: EMBL:AY208834 xref: EMBL:AY208835 xref: EMBL:AY208836 xref: EMBL:AY208837 xref: EMBL:AY208838 xref: EMBL:AY208839 xref: EMBL:AY208840 xref: EMBL:AY208841 xref: EMBL:AY208842 xref: EMBL:BC001628 xref: EMBL:BX538161 xref: HGNC:HGNC:15984 xref: UniGene:Hs.20158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005943 ! APTX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004087 name: ARAF_human def: "A-Raf proto-oncogene serine/threonine-protein kinase gene" [UniProtKB:P10398] synonym: "ARAF1" EXACT [UniProtKB:P10398] synonym: "PKS" EXACT [UniProtKB:P10398] synonym: "PKS2" EXACT [UniProtKB:P10398] xref: EMBL:AB158254 xref: EMBL:BC002466 xref: EMBL:BC007514 xref: EMBL:BT019864 xref: EMBL:L24038 xref: EMBL:M13829 xref: EMBL:U01337 xref: EMBL:X04790 xref: EMBL:Z84466 xref: HGNC:HGNC:646 xref: UniGene:Hs.446641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005708 ! ARAF_HUMAN relationship: codes_for CCO:B0056437 ! Q5H9B2_HUMAN relationship: codes_for CCO:B0058228 ! Q96II5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004088 name: ARD1A_human def: "N-terminal acetyltransferase complex ARD1 subunit homolog A gene" [UniProtKB:P41227] synonym: "ARD1" EXACT [UniProtKB:P41227] synonym: "TE2" EXACT [UniProtKB:P41227] xref: EMBL:BC000308 xref: EMBL:BC019312 xref: EMBL:X77588 xref: HGNC:HGNC:18704 xref: UniGene:Hs.433291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005243 ! ARD1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004089 name: ARFGAP1_human def: "ADP-ribosylation factor GTPase-activating protein 1 gene" [UniProtKB:Q8N6T3] synonym: "ARF1GAP" EXACT [UniProtKB:Q8N6T3] xref: EMBL:AB015340 xref: EMBL:AK001629 xref: EMBL:AK027268 xref: EMBL:AK027441 xref: EMBL:AL121827 xref: EMBL:AL137744 xref: EMBL:BC000786 xref: EMBL:BC006085 xref: EMBL:BC011876 xref: EMBL:BC028233 xref: HGNC:HGNC:15852 xref: UniGene:Hs.25584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006225 ! ARFG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004090 name: ARHGEF1_human def: "Rho guanine nucleotide exchange factor 1 gene" [UniProtKB:Q92888] xref: EMBL:BC005155 xref: EMBL:BC011726 xref: EMBL:BC015652 xref: EMBL:BC034013 xref: EMBL:BC035127 xref: EMBL:BC067262 xref: EMBL:BT007421 xref: EMBL:CH471126 xref: EMBL:U64105 xref: EMBL:Y09160 xref: HGNC:HGNC:681 xref: UniGene:Hs.631550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002023 ! ARHG1_HUMAN relationship: codes_for CCO:B0056305 ! Q49AN3_HUMAN relationship: codes_for CCO:B0056867 ! Q6NX52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004091 name: ARID1A_human def: "AT-rich interactive domain-containing protein 1A gene" [UniProtKB:O14497] synonym: "C1orf4" EXACT [UniProtKB:O14497] synonym: "OSA1" EXACT [UniProtKB:O14497] synonym: "SMARCF1" EXACT [UniProtKB:O14497] xref: EMBL:AB001895 xref: EMBL:AB024075 xref: EMBL:AF219114 xref: EMBL:AF231056 xref: EMBL:AF265208 xref: EMBL:AF268913 xref: EMBL:AF521670 xref: EMBL:AK223275 xref: EMBL:AL034380 xref: EMBL:AL512408 xref: HGNC:HGNC:11110 xref: UniGene:Hs.468972 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006007 ! ARI1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004092 name: ARIH2_human def: "Protein ariadne-2 homolog gene" [UniProtKB:O95376] synonym: "ARI2" EXACT [UniProtKB:O95376] synonym: "HT005" EXACT [UniProtKB:O95376] synonym: "TRIAD1" EXACT [UniProtKB:O95376] xref: EMBL:AF099149 xref: EMBL:AF183427 xref: EMBL:AJ130978 xref: EMBL:BC000422 xref: HGNC:HGNC:690 xref: UniGene:Hs.649132 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005288 ! ARI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004093 name: ARID4A_human def: "AT-rich interactive domain-containing protein 4A gene" [UniProtKB:P29374] synonym: "RBBP1" EXACT [UniProtKB:P29374] synonym: "RBP1" EXACT [UniProtKB:P29374] xref: EMBL:AL132989 xref: EMBL:AL139021 xref: EMBL:S57153 xref: EMBL:S57160 xref: EMBL:S57162 xref: EMBL:S66427 xref: HGNC:HGNC:9885 xref: UniGene:Hs.161000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005693 ! ARI4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004094 name: ARID2_human def: "AT-rich interactive domain-containing protein 2 gene" [UniProtKB:Q68CP9] synonym: "KIAA1557" EXACT [UniProtKB:Q68CP9] xref: EMBL:AB046777 xref: EMBL:AK027718 xref: EMBL:AK127872 xref: EMBL:AL832200 xref: EMBL:AY727870 xref: EMBL:BC090062 xref: EMBL:BX537879 xref: EMBL:CR749833 xref: EMBL:DQ096628 xref: HGNC:HGNC:18037 xref: UniGene:Hs.696080 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005497 ! ARID2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004095 name: ARL3_human def: "ADP-ribosylation factor-like protein 3 gene" [UniProtKB:P36405] synonym: "ARFL3" EXACT [UniProtKB:P36405] xref: EMBL:AF493889 xref: EMBL:AL391121 xref: EMBL:BC009841 xref: EMBL:U07151 xref: HGNC:HGNC:694 xref: UniGene:Hs.182215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006120 ! ARL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004096 name: ARL4D_human def: "ADP-ribosylation factor-like protein 4D gene" [UniProtKB:P49703] synonym: "ARF4L" EXACT [UniProtKB:P49703] xref: EMBL:AB060692 xref: EMBL:BC000043 xref: EMBL:L38490 xref: EMBL:U25771 xref: HGNC:HGNC:656 xref: UniGene:Hs.183153 xref: UniGene:Hs.705646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006256 ! ARL4D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004097 name: ARL8B_human def: "ADP-ribosylation factor-like protein 8B gene" [UniProtKB:Q9NVJ2] synonym: "ARL10C" EXACT [UniProtKB:Q9NVJ2] synonym: "GIE1" EXACT [UniProtKB:Q9NVJ2] xref: EMBL:AB118751 xref: EMBL:AK001564 xref: EMBL:BC013131 xref: EMBL:BC063125 xref: EMBL:CR457264 xref: HGNC:HGNC:25564 xref: UniGene:Hs.250009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006324 ! ARL8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004098 name: ARNT2_human def: "Aryl hydrocarbon receptor nuclear translocator 2 gene" [UniProtKB:Q9HBZ2] synonym: "KIAA0307" EXACT [UniProtKB:Q9HBZ2] xref: EMBL:AB002305 xref: EMBL:AF185593 xref: EMBL:AF185594 xref: EMBL:AF185595 xref: EMBL:AF185596 xref: EMBL:AF185597 xref: EMBL:AF185598 xref: EMBL:AF185599 xref: EMBL:AF185600 xref: EMBL:AF185601 xref: EMBL:AF185602 xref: EMBL:AF185603 xref: EMBL:AF185604 xref: EMBL:AF185605 xref: EMBL:AF185606 xref: EMBL:AF185607 xref: EMBL:AF185608 xref: EMBL:AF185609 xref: EMBL:AF185610 xref: EMBL:BC036099 xref: HGNC:HGNC:16876 xref: UniGene:Hs.459070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006033 ! ARNT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004099 name: ARNT_human def: "Aryl hydrocarbon receptor nuclear translocator gene" [UniProtKB:P27540] xref: EMBL:AF001307 xref: EMBL:AJ251863 xref: EMBL:AJ404851 xref: EMBL:AJ404852 xref: EMBL:AJ404853 xref: EMBL:AJ404854 xref: EMBL:AY430083 xref: EMBL:M69238 xref: EMBL:Y18859 xref: HGNC:HGNC:700 xref: UniGene:Hs.632446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005551 ! ARNT_HUMAN relationship: codes_for CCO:B0054479 ! O43392_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004100 name: ACTR6_human def: "Actin-related protein 6 gene" [UniProtKB:Q9GZN1] synonym: "CDA12" EXACT [UniProtKB:Q9GZN1] xref: EMBL:AB038229 xref: EMBL:AF212251 xref: EMBL:AK023495 xref: EMBL:AK023684 xref: EMBL:BC015107 xref: HGNC:HGNC:24025 xref: UniGene:Hs.115088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005367 ! ARP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004101 name: ACTR8_human def: "Actin-related protein 8 gene" [UniProtKB:Q9H981] synonym: "INO80N" EXACT [UniProtKB:Q9H981] xref: EMBL:AK022996 xref: EMBL:AK026232 xref: HGNC:HGNC:14672 xref: UniGene:Hs.412186 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006058 ! ARP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004102 name: ARPC3_human def: "Actin-related protein 2/3 complex subunit 3 gene" [UniProtKB:O15145] synonym: "ARC21" EXACT [UniProtKB:O15145] xref: EMBL:AC144548 xref: EMBL:AF004561 xref: EMBL:AF006086 xref: EMBL:BC067747 xref: EMBL:BC078162 xref: EMBL:CR407667 xref: HGNC:HGNC:706 xref: UniGene:Hs.524741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006172 ! ARPC3_HUMAN relationship: codes_for CCO:B0054134 ! A8MYY8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004103 name: ARSE_human def: "Arylsulfatase E precursor gene" [UniProtKB:P51690] xref: EMBL:AK223183 xref: EMBL:AK223199 xref: EMBL:X83573 xref: HGNC:HGNC:719 xref: UniGene:Hs.386975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006258 ! ARSE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004104 name: ASCC2_human def: "Activating signal cointegrator 1 complex subunit 2 gene" [UniProtKB:Q9H1I8] synonym: "ASC1P100" EXACT [UniProtKB:Q9H1I8] xref: EMBL:AC004882 xref: EMBL:AK022886 xref: EMBL:AK025241 xref: EMBL:AY013289 xref: EMBL:BC025368 xref: EMBL:Z82171 xref: HGNC:HGNC:24103 xref: UniGene:Hs.517438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006086 ! ASCC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004105 name: PYCARD_human def: "Apoptosis-associated speck-like protein containing a CARD gene" [UniProtKB:Q9ULZ3] synonym: "ASC" EXACT [UniProtKB:Q9ULZ3] synonym: "CARD5" EXACT [UniProtKB:Q9ULZ3] synonym: "TMS1" EXACT [UniProtKB:Q9ULZ3] xref: EMBL:AB023416 xref: EMBL:AF184072 xref: EMBL:AF184073 xref: EMBL:AF255794 xref: EMBL:AF310103 xref: EMBL:AF384665 xref: EMBL:AK000211 xref: EMBL:BC004470 xref: EMBL:BC013569 xref: HGNC:HGNC:16608 xref: UniGene:Hs.499094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002228 ! ASC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004106 name: ASF1A_human def: "Histone chaperone ASF1A gene" [UniProtKB:Q9Y294] synonym: "CGI-98" EXACT [UniProtKB:Q9Y294] synonym: "HSPC146" EXACT [UniProtKB:Q9Y294] xref: EMBL:AB028628 xref: EMBL:AF151856 xref: EMBL:AF161495 xref: EMBL:AF279306 xref: EMBL:AK025738 xref: EMBL:AL050261 xref: EMBL:BC010878 xref: EMBL:CR457347 xref: HGNC:HGNC:20995 xref: UniGene:Hs.292316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005268 ! ASF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004107 name: ASH2L_human def: "Set1/Ash2 histone methyltransferase complex subunit ASH2 gene" [UniProtKB:Q9UBL3] synonym: "ASH2L1" EXACT [UniProtKB:Q9UBL3] xref: EMBL:AB020982 xref: EMBL:AB022785 xref: EMBL:AF056717 xref: EMBL:AF056718 xref: EMBL:BC015936 xref: HGNC:HGNC:744 xref: UniGene:Hs.521530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005614 ! ASH2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004108 name: ASPM_human def: "Abnormal spindle-like microcephaly-associated protein gene" [UniProtKB:Q8IZT6] synonym: "MCPH5" EXACT [UniProtKB:Q8IZT6] xref: EMBL:AF509326 xref: EMBL:AK001379 xref: EMBL:AK001411 xref: EMBL:AL353809 xref: EMBL:AY099890 xref: EMBL:AY099891 xref: EMBL:AY099892 xref: EMBL:AY099893 xref: EMBL:AY101201 xref: EMBL:AY367065 xref: EMBL:BC015396 xref: EMBL:BC034607 xref: EMBL:CH471067 xref: HGNC:HGNC:19048 xref: UniGene:Hs.121028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001956 ! ASPM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004109 name: PPP1R13B_human def: "Apoptosis-stimulating of p53 protein 1 gene" [UniProtKB:Q96KQ4] synonym: "ASPP1" EXACT [UniProtKB:Q96KQ4] synonym: "KIAA0771" EXACT [UniProtKB:Q96KQ4] xref: EMBL:AB018314 xref: EMBL:AJ318887 xref: EMBL:AL049840 xref: HGNC:HGNC:14950 xref: UniGene:Hs.436113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002046 ! ASPP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004110 name: TP53BP2_human def: "Apoptosis-stimulating of p53 protein 2 gene" [UniProtKB:Q13625] synonym: "ASPP2" EXACT [UniProtKB:Q13625] synonym: "BBP" EXACT [UniProtKB:Q13625] xref: EMBL:AJ318888 xref: EMBL:BC046150 xref: EMBL:BC058918 xref: EMBL:U09582 xref: EMBL:U58334 xref: HGNC:HGNC:12000 xref: UniGene:Hs.523968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001764 ! ASPP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004111 name: ATP1A1_human def: "Sodium/potassium-transporting ATPase subunit alpha-1 precursor gene" [UniProtKB:P05023] xref: EMBL:AL136376 xref: EMBL:BC001330 xref: EMBL:BC003077 xref: EMBL:BC050359 xref: EMBL:D00099 xref: EMBL:J03007 xref: EMBL:L76938 xref: EMBL:M16793 xref: EMBL:M16794 xref: EMBL:M27572 xref: EMBL:M27579 xref: EMBL:M30309 xref: EMBL:M30310 xref: EMBL:U16798 xref: EMBL:X03757 xref: EMBL:X04297 xref: HGNC:HGNC:799 xref: UniGene:Hs.371889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005459 ! AT1A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004112 name: ATP1B1_human def: "Sodium/potassium-transporting ATPase subunit beta-1 gene" [UniProtKB:P05026] synonym: "ATP1B" EXACT [UniProtKB:P05026] xref: EMBL:AL031726 xref: EMBL:BC000006 xref: EMBL:BT009787 xref: EMBL:M25160 xref: EMBL:M25161 xref: EMBL:U16799 xref: EMBL:X03747 xref: EMBL:X17161 xref: HGNC:HGNC:804 xref: UniGene:Hs.291196 xref: UniGene:Hs.702359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005453 ! AT1B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004113 name: ATP2A2_human def: "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 gene" [UniProtKB:P16615] synonym: "ATP2B" EXACT [UniProtKB:P16615] xref: EMBL:BC035588 xref: EMBL:M23114 xref: EMBL:M23115 xref: EMBL:M23116 xref: EMBL:M23278 xref: HGNC:HGNC:812 xref: UniGene:Hs.506759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005840 ! AT2A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004114 name: ATF3_human def: "Cyclic AMP-dependent transcription factor ATF-3 gene" [UniProtKB:P18847] xref: EMBL:AB066566 xref: EMBL:AB078026 xref: EMBL:AB078027 xref: EMBL:AK294296 xref: EMBL:AL590648 xref: EMBL:AY313926 xref: EMBL:AY313927 xref: EMBL:AY426987 xref: EMBL:BC006322 xref: EMBL:CH471100 xref: EMBL:L19871 xref: HGNC:HGNC:785 xref: UniGene:Hs.460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006121 ! ATF3_HUMAN relationship: codes_for CCO:B0056651 ! Q5VTZ2_HUMAN relationship: codes_for CCO:B0056652 ! Q5VTZ4_HUMAN relationship: codes_for CCO:B0057172 ! Q7Z566_HUMAN relationship: codes_for CCO:B0057173 ! Q7Z567_HUMAN relationship: codes_for CCO:B0058045 ! Q8WYM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004115 name: ATF5_human def: "Cyclic AMP-dependent transcription factor ATF-5 gene" [UniProtKB:Q9Y2D1] synonym: "ATFX" EXACT [UniProtKB:Q9Y2D1] xref: EMBL:AB021663 xref: EMBL:AB073613 xref: EMBL:AF101388 xref: EMBL:AF305687 xref: EMBL:BC005174 xref: HGNC:HGNC:790 xref: UniGene:Hs.9754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002251 ! ATF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004116 name: ATF7_human def: "Cyclic AMP-dependent transcription factor ATF-7 gene" [UniProtKB:P17544] synonym: "ATFA" EXACT [UniProtKB:P17544] xref: EMBL:X52943 xref: EMBL:X57197 xref: HGNC:HGNC:792 xref: UniGene:Hs.12286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006016 ! ATF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004117 name: ATM_human def: "Serine-protein kinase ATM gene" [UniProtKB:Q13315] xref: EMBL:AY220758 xref: EMBL:U26455 xref: EMBL:U33841 xref: EMBL:U55704 xref: EMBL:U55705 xref: EMBL:U55707 xref: EMBL:U55708 xref: EMBL:U55709 xref: EMBL:U55710 xref: EMBL:U55711 xref: EMBL:U55712 xref: EMBL:U55713 xref: EMBL:U55714 xref: EMBL:U55715 xref: EMBL:U55716 xref: EMBL:U55717 xref: EMBL:U55718 xref: EMBL:U55719 xref: EMBL:U55720 xref: EMBL:U55721 xref: EMBL:U55722 xref: EMBL:U55723 xref: EMBL:U55724 xref: EMBL:U55725 xref: EMBL:U55726 xref: EMBL:U55727 xref: EMBL:U55728 xref: EMBL:U55729 xref: EMBL:U55730 xref: EMBL:U55731 xref: EMBL:U55732 xref: EMBL:U55733 xref: EMBL:U55734 xref: EMBL:U55735 xref: EMBL:U55736 xref: EMBL:U55737 xref: EMBL:U55738 xref: EMBL:U55739 xref: EMBL:U55740 xref: EMBL:U55741 xref: EMBL:U55742 xref: EMBL:U55743 xref: EMBL:U55744 xref: EMBL:U55745 xref: EMBL:U55746 xref: EMBL:U55747 xref: EMBL:U55748 xref: EMBL:U55749 xref: EMBL:U55750 xref: EMBL:U55751 xref: EMBL:U55752 xref: EMBL:U55753 xref: EMBL:U55754 xref: EMBL:U55755 xref: EMBL:U55756 xref: EMBL:U55757 xref: EMBL:U67092 xref: EMBL:U82828 xref: EMBL:X91196 xref: HGNC:HGNC:795 xref: UniGene:Hs.367437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001750 ! ATM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004118 name: ATN1_human def: "Atrophin-1 gene" [UniProtKB:P54259] synonym: "D12S755E" EXACT [UniProtKB:P54259] synonym: "DRPLA" EXACT [UniProtKB:P54259] xref: EMBL:D31840 xref: EMBL:D38529 xref: EMBL:D63808 xref: EMBL:L10377 xref: EMBL:U23851 xref: EMBL:U47924 xref: HGNC:HGNC:3033 xref: UniGene:Hs.143766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005944 ! ATN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004119 name: ATP5A1_human def: "ATP synthase subunit alpha, mitochondrial precursor gene" [UniProtKB:P25705] synonym: "ATP5A" EXACT [UniProtKB:P25705] synonym: "ATP5AL2" EXACT [UniProtKB:P25705] synonym: "ATPM" EXACT [UniProtKB:P25705] xref: EMBL:BC003119 xref: EMBL:BC007299 xref: EMBL:BC008028 xref: EMBL:BC011384 xref: EMBL:BC016046 xref: EMBL:BC019310 xref: EMBL:BC039135 xref: EMBL:BC064562 xref: EMBL:BC067385 xref: EMBL:BT007209 xref: EMBL:D14710 xref: EMBL:D28126 xref: EMBL:X59066 xref: EMBL:X65460 xref: HGNC:HGNC:823 xref: UniGene:Hs.298280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005778 ! ATPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004120 name: ATP5B_human def: "ATP synthase subunit beta, mitochondrial precursor gene" [UniProtKB:P06576] synonym: "ATPMB" EXACT [UniProtKB:P06576] synonym: "ATPSB" EXACT [UniProtKB:P06576] xref: EMBL:BC016512 xref: EMBL:D00022 xref: EMBL:M19482 xref: EMBL:M19483 xref: EMBL:M27132 xref: EMBL:X03559 xref: EMBL:X05606 xref: HGNC:HGNC:830 xref: UniGene:Hs.406510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005827 ! ATPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004121 name: ATP5C1_human def: "ATP synthase subunit gamma, mitochondrial precursor gene" [UniProtKB:P36542] synonym: "ATP5C" EXACT [UniProtKB:P36542] synonym: "ATP5CL1" EXACT [UniProtKB:P36542] xref: EMBL:AL158044 xref: EMBL:AL353754 xref: EMBL:BC000470 xref: EMBL:BC000931 xref: EMBL:BC013394 xref: EMBL:BC016812 xref: EMBL:BC020824 xref: EMBL:D16561 xref: EMBL:D16562 xref: EMBL:D16563 xref: HGNC:HGNC:833 xref: UniGene:Hs.271135 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006122 ! ATPG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004122 name: ATRIP_human def: "ATR-interacting protein gene" [UniProtKB:Q8WXE1] synonym: "AGS1" EXACT [UniProtKB:Q8WXE1] xref: EMBL:AF451323 xref: EMBL:AK022405 xref: EMBL:BC014153 xref: EMBL:BC020563 xref: EMBL:BC030597 xref: HGNC:HGNC:33499 xref: UniGene:Hs.694840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002009 ! ATRIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004123 name: ATRX_human def: "Transcriptional regulator ATRX gene" [UniProtKB:P46100] synonym: "RAD54L" EXACT [UniProtKB:P46100] synonym: "XH2" EXACT [UniProtKB:P46100] xref: EMBL:AB101681 xref: EMBL:AB101682 xref: EMBL:AB101683 xref: EMBL:AB101684 xref: EMBL:AB101685 xref: EMBL:AB101686 xref: EMBL:AB101687 xref: EMBL:AB101688 xref: EMBL:AB101689 xref: EMBL:AB101690 xref: EMBL:AB101691 xref: EMBL:AB101692 xref: EMBL:AB101693 xref: EMBL:AB101694 xref: EMBL:AB101695 xref: EMBL:AB101696 xref: EMBL:AB101697 xref: EMBL:AB101698 xref: EMBL:AB101699 xref: EMBL:AB101700 xref: EMBL:AB102641 xref: EMBL:AB208928 xref: EMBL:AB209545 xref: EMBL:AF000157 xref: EMBL:AF000158 xref: EMBL:AF000159 xref: EMBL:AF000160 xref: EMBL:AL109753 xref: EMBL:AL121874 xref: EMBL:L34363 xref: EMBL:U09820 xref: EMBL:U72904 xref: EMBL:U72905 xref: EMBL:U72907 xref: EMBL:U72908 xref: EMBL:U72909 xref: EMBL:U72910 xref: EMBL:U72911 xref: EMBL:U72912 xref: EMBL:U72913 xref: EMBL:U72914 xref: EMBL:U72915 xref: EMBL:U72916 xref: EMBL:U72917 xref: EMBL:U72918 xref: EMBL:U72919 xref: EMBL:U72920 xref: EMBL:U72921 xref: EMBL:U72922 xref: EMBL:U72923 xref: EMBL:U72924 xref: EMBL:U72925 xref: EMBL:U72926 xref: EMBL:U72927 xref: EMBL:U72928 xref: EMBL:U72929 xref: EMBL:U72930 xref: EMBL:U72931 xref: EMBL:U72932 xref: EMBL:U72933 xref: EMBL:U72934 xref: EMBL:U72935 xref: EMBL:U72936 xref: EMBL:U72937 xref: EMBL:U72938 xref: EMBL:U75653 xref: EMBL:U97080 xref: EMBL:U97081 xref: EMBL:U97082 xref: EMBL:U97083 xref: EMBL:U97084 xref: EMBL:U97085 xref: EMBL:U97086 xref: EMBL:U97087 xref: EMBL:U97088 xref: EMBL:U97089 xref: EMBL:U97090 xref: EMBL:U97091 xref: EMBL:U97092 xref: EMBL:U97093 xref: EMBL:U97094 xref: EMBL:U97095 xref: EMBL:U97096 xref: EMBL:U97097 xref: EMBL:U97098 xref: EMBL:U97099 xref: EMBL:U97100 xref: EMBL:U97101 xref: EMBL:U97102 xref: EMBL:U97103 xref: EMBL:X83753 xref: EMBL:Z84487 xref: HGNC:HGNC:886 xref: UniGene:Hs.533526 xref: UniGene:Hs.653797 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005879 ! ATRX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004124 name: ATR_human def: "Serine/threonine-protein kinase ATR gene" [UniProtKB:Q13535] synonym: "FRP1" EXACT [UniProtKB:Q13535] xref: EMBL:AF325699 xref: EMBL:U49844 xref: EMBL:U76308 xref: EMBL:Y09077 xref: HGNC:HGNC:882 xref: UniGene:Hs.271791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001756 ! ATR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004125 name: ATXN10_human def: "Ataxin-10 gene" [UniProtKB:Q9UBB4] synonym: "SCA10" EXACT [UniProtKB:Q9UBB4] xref: EMBL:AF119662 xref: EMBL:AL050282 xref: EMBL:BC007508 xref: EMBL:CR456568 xref: EMBL:CR457381 xref: EMBL:Z84478 xref: EMBL:Z93784 xref: EMBL:Z95331 xref: HGNC:HGNC:10549 xref: UniGene:Hs.475125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005816 ! ATX10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004126 name: ATXN1_human def: "Ataxin-1 gene" [UniProtKB:P54253] synonym: "ATX1" EXACT [UniProtKB:P54253] synonym: "SCA1" EXACT [UniProtKB:P54253] xref: EMBL:AL009031 xref: EMBL:BC117125 xref: EMBL:S82497 xref: EMBL:X79204 xref: HGNC:HGNC:10548 xref: UniGene:Hs.434961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005425 ! ATX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004127 name: ATXN2_human def: "Ataxin-2 gene" [UniProtKB:Q99700] synonym: "ATX2" EXACT [UniProtKB:Q99700] synonym: "SCA2" EXACT [UniProtKB:Q99700] synonym: "TNRC13" EXACT [UniProtKB:Q99700] xref: EMBL:AC002395 xref: EMBL:AK128613 xref: EMBL:U70323 xref: EMBL:Y08262 xref: HGNC:HGNC:10555 xref: UniGene:Hs.76253 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005988 ! ATX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004128 name: ATXN7_human def: "Ataxin-7 gene" [UniProtKB:O15265] synonym: "SCA7" EXACT [UniProtKB:O15265] xref: EMBL:AA398030 xref: EMBL:AF032102 xref: EMBL:AF032103 xref: EMBL:AF032105 xref: EMBL:AJ000517 xref: HGNC:HGNC:10560 xref: UniGene:Hs.476595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005945 ! ATX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004129 name: AURKB_human def: "Serine/threonine-protein kinase 12 gene" [UniProtKB:Q96GD4] synonym: "AIK2" EXACT [UniProtKB:Q96GD4] synonym: "AIM1" EXACT [UniProtKB:Q96GD4] synonym: "ARK2" EXACT [UniProtKB:Q96GD4] synonym: "STK12" EXACT [UniProtKB:Q96GD4] xref: EMBL:AB011446 xref: EMBL:AB011450 xref: EMBL:AF004022 xref: EMBL:AF008552 xref: EMBL:AF015254 xref: EMBL:BC000442 xref: EMBL:BC009751 xref: EMBL:BC013300 xref: EMBL:BC080581 xref: EMBL:BT019534 xref: HGNC:HGNC:11390 xref: UniGene:Hs.442658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002040 ! AURKB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004130 name: AURKC_human def: "Serine/threonine-protein kinase 13 gene" [UniProtKB:Q9UQB9] synonym: "AIE2" EXACT [UniProtKB:Q9UQB9] synonym: "AIK3" EXACT [UniProtKB:Q9UQB9] synonym: "STK13" EXACT [UniProtKB:Q9UQB9] xref: EMBL:AB017332 xref: EMBL:AC005261 xref: EMBL:AF054621 xref: EMBL:AF059681 xref: HGNC:HGNC:11391 xref: UniGene:Hs.98338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002242 ! AURKC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004131 name: AVPI1_human def: "Arginine vasopressin-induced protein 1 gene" [UniProtKB:Q5T686] synonym: "NPD013" EXACT [UniProtKB:Q5T686] synonym: "PP5395" EXACT [UniProtKB:Q5T686] xref: EMBL:AF218019 xref: EMBL:AF241786 xref: EMBL:AK222493 xref: EMBL:AK223099 xref: EMBL:AL355315 xref: EMBL:BC000877 xref: HGNC:HGNC:30898 xref: UniGene:Hs.23918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001879 ! AVPI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004132 name: ACVR2A_human def: "Activin receptor type-2A precursor gene" [UniProtKB:P27037] synonym: "ACVR2" EXACT [UniProtKB:P27037] xref: EMBL:AC009480 xref: EMBL:BC067417 xref: EMBL:BC067418 xref: EMBL:BC069707 xref: EMBL:D31770 xref: EMBL:M93415 xref: EMBL:X62381 xref: EMBL:X63128 xref: HGNC:HGNC:173 xref: UniGene:Hs.470174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005543 ! AVR2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004133 name: AXIN1_human def: "Axin-1 gene" [UniProtKB:O15169] synonym: "AXIN" EXACT [UniProtKB:O15169] xref: EMBL:AC005202 xref: EMBL:AE006463 xref: EMBL:AF009674 xref: EMBL:BC017447 xref: EMBL:BC044648 xref: EMBL:Z69667 xref: EMBL:Z99754 xref: HGNC:HGNC:903 xref: UniGene:Hs.592082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001367 ! AXN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004134 name: BAD_human def: "Bcl2 antagonist of cell death gene" [UniProtKB:Q92934] synonym: "BBC6" EXACT [UniProtKB:Q92934] synonym: "BCL2L8" EXACT [UniProtKB:Q92934] xref: EMBL:AF021792 xref: EMBL:AF031523 xref: EMBL:BC001901 xref: EMBL:BT006678 xref: EMBL:U66879 xref: HGNC:HGNC:936 xref: UniGene:Hs.370254 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005175 ! BAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004135 name: BAK1_human def: "Bcl-2 homologous antagonist/killer gene" [UniProtKB:Q16611] synonym: "BAK" EXACT [UniProtKB:Q16611] synonym: "BCL2L7" EXACT [UniProtKB:Q16611] synonym: "CDN1" EXACT [UniProtKB:Q16611] xref: EMBL:AY260471 xref: EMBL:BC004431 xref: EMBL:BC110337 xref: EMBL:CH471081 xref: EMBL:D88397 xref: EMBL:U16811 xref: EMBL:U23765 xref: EMBL:X84213 xref: EMBL:Z93017 xref: HGNC:HGNC:949 xref: UniGene:Hs.485139 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005420 ! BAK_HUMAN relationship: codes_for CCO:B0056236 ! Q2YD93_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004136 name: BANP_human def: "Protein BANP gene" [UniProtKB:Q8N9N5] synonym: "SMAR1" EXACT [UniProtKB:Q8N9N5] xref: EMBL:AC127455 xref: EMBL:AK000545 xref: EMBL:AK094158 xref: EMBL:BC009424 xref: HGNC:HGNC:13450 xref: UniGene:Hs.461705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001971 ! BANP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004137 name: BCAP31_human def: "B-cell receptor-associated protein 31 gene" [UniProtKB:P51572] synonym: "BAP31" EXACT [UniProtKB:P51572] synonym: "DXS1357E" EXACT [UniProtKB:P51572] xref: EMBL:BC014323 xref: EMBL:BC065292 xref: EMBL:U36341 xref: EMBL:U52111 xref: EMBL:X81109 xref: EMBL:X81817 xref: EMBL:Z31696 xref: HGNC:HGNC:16695 xref: UniGene:Hs.522817 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005676 ! BAP31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004138 name: BARD1_human def: "BRCA1-associated RING domain protein 1 gene" [UniProtKB:Q99728] xref: EMBL:AC016708 xref: EMBL:AF038034 xref: EMBL:AF038035 xref: EMBL:AF038036 xref: EMBL:AF038037 xref: EMBL:AF038038 xref: EMBL:AF038039 xref: EMBL:AF038040 xref: EMBL:AF038041 xref: EMBL:AF038042 xref: EMBL:BC126426 xref: EMBL:U76638 xref: HGNC:HGNC:952 xref: UniGene:Hs.591642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002086 ! BARD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004139 name: BAT2_human def: "Large proline-rich protein BAT2 gene" [UniProtKB:P48634] synonym: "G2" EXACT [UniProtKB:P48634] xref: EMBL:AB210034 xref: EMBL:AF129756 xref: EMBL:AL662801 xref: EMBL:AL662847 xref: EMBL:AL805934 xref: EMBL:BA000025 xref: EMBL:BC030127 xref: EMBL:BC032134 xref: EMBL:BC042295 xref: EMBL:BC060668 xref: EMBL:BX511262 xref: EMBL:CR749245 xref: EMBL:M33509 xref: EMBL:M33512 xref: EMBL:M33518 xref: EMBL:Z15025 xref: HGNC:HGNC:13918 xref: UniGene:Hs.123239 xref: UniGene:Hs.436093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005898 ! BAT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004140 name: BAT3_human def: "Large proline-rich protein BAT3 gene" [UniProtKB:P46379] synonym: "G3" EXACT [UniProtKB:P46379] xref: EMBL:AF129756 xref: EMBL:AL662801 xref: EMBL:AL662847 xref: EMBL:AL670886 xref: EMBL:AL805934 xref: EMBL:BA000025 xref: EMBL:BC003133 xref: EMBL:BX511262 xref: EMBL:BX647244 xref: EMBL:M33519 xref: EMBL:M33520 xref: EMBL:M33521 xref: HGNC:HGNC:13919 xref: UniGene:Hs.440900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006127 ! BAT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004141 name: BAT5_human def: "Protein BAT5 gene" [UniProtKB:O95870] synonym: "G5" EXACT [UniProtKB:O95870] synonym: "NG26" EXACT [UniProtKB:O95870] synonym: "PP199" EXACT [UniProtKB:O95870] xref: EMBL:AF129756 xref: EMBL:AF193047 xref: EMBL:AK001207 xref: EMBL:AK023194 xref: EMBL:AL662899 xref: EMBL:AL670886 xref: EMBL:AL805934 xref: EMBL:BA000025 xref: EMBL:BC031839 xref: EMBL:BX248244 xref: EMBL:BX511262 xref: HGNC:HGNC:13921 xref: UniGene:Hs.388188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005571 ! BAT5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004142 name: BATF_human def: "Basic leucine zipper transcriptional factor ATF-like gene" [UniProtKB:Q16520] xref: EMBL:AC007182 xref: EMBL:AF016898 xref: EMBL:BC032294 xref: EMBL:D42106 xref: EMBL:U15460 xref: HGNC:HGNC:958 xref: UniGene:Hs.509964 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005320 ! BATF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004143 name: BAX_human def: "Apoptosis regulator BAX gene" [UniProtKB:Q07812] xref: EMBL:AF007826 xref: EMBL:AF247393 xref: EMBL:AF250190 xref: EMBL:AJ417988 xref: EMBL:AY217036 xref: EMBL:BC014175 xref: EMBL:CH471177 xref: EMBL:L22473 xref: EMBL:L22474 xref: EMBL:L22475 xref: EMBL:U19599 xref: HGNC:HGNC:959 xref: UniGene:Hs.631546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001723 ! BAX_HUMAN relationship: codes_for CCO:B0016462 ! Q9NYG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004144 name: BBC3_human def: "Bcl-2-binding component 3 gene" [UniProtKB:Q9BXH1] synonym: "PUMA" EXACT [UniProtKB:Q9BXH1] xref: EMBL:AF332558 xref: EMBL:AF354654 xref: EMBL:AF354655 xref: EMBL:U82987 xref: HGNC:HGNC:17868 xref: UniGene:Hs.467020 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005848 ! BBC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004145 name: BCL11A_human def: "B-cell lymphoma/leukemia 11A gene" [UniProtKB:Q9H165] synonym: "CTIP1" EXACT [UniProtKB:Q9H165] synonym: "EVI9" EXACT [UniProtKB:Q9H165] synonym: "KIAA1809" EXACT [UniProtKB:Q9H165] xref: EMBL:AB058712 xref: EMBL:AF080216 xref: EMBL:AJ404611 xref: EMBL:AJ404612 xref: EMBL:AJ404613 xref: EMBL:AK001035 xref: EMBL:AY228763 xref: EMBL:BC021098 xref: HGNC:HGNC:13221 xref: UniGene:Hs.370549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006020 ! BC11A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004146 name: BCAR1_human def: "Breast cancer anti-estrogen resistance protein 1 gene" [UniProtKB:P56945] synonym: "CAS" EXACT [UniProtKB:P56945] synonym: "CASS1" EXACT [UniProtKB:P56945] synonym: "CRKAS" EXACT [UniProtKB:P56945] xref: EMBL:AB040024 xref: EMBL:AF218451 xref: EMBL:AJ242987 xref: EMBL:AK027608 xref: EMBL:AY545071 xref: EMBL:BC062556 xref: HGNC:HGNC:971 xref: UniGene:Hs.479747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005841 ! BCAR1_HUMAN relationship: codes_for CCO:B0056892 ! Q6P5Z4_HUMAN relationship: codes_for CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004147 name: BCAR3_human def: "Breast cancer anti-estrogen resistance protein 3 gene" [UniProtKB:O75815] synonym: "NSP2" EXACT [UniProtKB:O75815] synonym: "SH2D3B" EXACT [UniProtKB:O75815] synonym: "UNQ271/PRO308" EXACT [UniProtKB:O75815] xref: EMBL:AF124250 xref: EMBL:AL109613 xref: EMBL:AL359820 xref: EMBL:AY358996 xref: EMBL:BC039895 xref: EMBL:CH471097 xref: EMBL:U92715 xref: HGNC:HGNC:973 xref: UniGene:Hs.36958 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001437 ! BCAR3_HUMAN relationship: codes_for CCO:B0022936 ! Q5TEW3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004148 name: BCAT1_human def: "Branched-chain-amino-acid aminotransferase, cytosolic gene" [UniProtKB:P54687] synonym: "BCT1" EXACT [UniProtKB:P54687] synonym: "ECA39" EXACT [UniProtKB:P54687] xref: EMBL:AC023796 xref: EMBL:AC026310 xref: EMBL:AC092867 xref: EMBL:AK056255 xref: EMBL:U21551 xref: HGNC:HGNC:976 xref: UniGene:Hs.438993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001671 ! BCAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004149 name: BCCIP_human def: "BRCA2 and CDKN1A-interacting protein gene" [UniProtKB:Q9P287] synonym: "TOK1" EXACT [UniProtKB:Q9P287] xref: EMBL:AB040450 xref: EMBL:AB040451 xref: EMBL:AL360176 xref: EMBL:AL834458 xref: EMBL:AY064247 xref: EMBL:AY064248 xref: EMBL:AY064249 xref: EMBL:BC009771 xref: HGNC:HGNC:978 xref: UniGene:Hs.370292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002187 ! BCCIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004150 name: BCL10_human def: "B-cell lymphoma/leukemia 10 gene" [UniProtKB:O95999] synonym: "CIPER" EXACT [UniProtKB:O95999] synonym: "CLAP" EXACT [UniProtKB:O95999] xref: EMBL:AF057700 xref: EMBL:AF082283 xref: EMBL:AF097732 xref: EMBL:AF100338 xref: EMBL:AF105066 xref: EMBL:AF127386 xref: EMBL:AF134395 xref: EMBL:AJ006288 xref: EMBL:BC053617 xref: HGNC:HGNC:989 xref: UniGene:Hs.193516 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001458 ! BCL10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004151 name: BCL2_human def: "Apoptosis regulator Bcl-2 gene" [UniProtKB:P10415] xref: EMBL:AY220759 xref: EMBL:BC027258 xref: EMBL:M13994 xref: EMBL:M13995 xref: EMBL:M14745 xref: EMBL:S72602 xref: EMBL:X06487 xref: HGNC:HGNC:990 xref: UniGene:Hs.150749 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001506 ! BCL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004152 name: BCL3_human def: "B-cell lymphoma 3-encoded protein gene" [UniProtKB:P20749] synonym: "BCL4" EXACT [UniProtKB:P20749] synonym: "D19S37" EXACT [UniProtKB:P20749] xref: EMBL:BC064993 xref: EMBL:M31731 xref: EMBL:M31732 xref: EMBL:U05681 xref: EMBL:U05822 xref: HGNC:HGNC:998 xref: UniGene:Hs.31210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005513 ! BCL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004153 name: BCL6_human def: "B-cell lymphoma 6 protein gene" [UniProtKB:P41182] synonym: "BCL5" EXACT [UniProtKB:P41182] synonym: "LAZ3" EXACT [UniProtKB:P41182] synonym: "ZBTB27" EXACT [UniProtKB:P41182] synonym: "ZNF51" EXACT [UniProtKB:P41182] xref: EMBL:S67779 xref: EMBL:U00115 xref: EMBL:Z21943 xref: HGNC:HGNC:1001 xref: UniGene:Hs.478588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001603 ! BCL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004154 name: BCL9_human def: "B-cell CLL/lymphoma 9 protein gene" [UniProtKB:O00512] xref: EMBL:AL359207 xref: EMBL:CH471223 xref: EMBL:Y13620 xref: HGNC:HGNC:1008 xref: UniGene:Hs.415209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006061 ! BCL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004155 name: BCL2L1_human def: "Apoptosis regulator Bcl-X gene" [UniProtKB:Q07817] synonym: "BCL2L" EXACT [UniProtKB:Q07817] synonym: "BCLX" EXACT [UniProtKB:Q07817] xref: EMBL:AL117381 xref: EMBL:AL160175 xref: EMBL:BC019307 xref: EMBL:BT007208 xref: EMBL:U72398 xref: EMBL:Z23115 xref: EMBL:Z23116 xref: HGNC:HGNC:992 xref: UniGene:Hs.516966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005901 ! BCLX_HUMAN relationship: codes_for CCO:B0028579 ! Q9H1R6_HUMAN relationship: codes_for CCO:B0028580 ! Q5QP56_HUMAN relationship: codes_for CCO:B0028581 ! Q5QP59_HUMAN relationship: codes_for CCO:B0028582 ! Q5TE64_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004156 name: BCR_human def: "Breakpoint cluster region protein gene" [UniProtKB:P11274] synonym: "BCR1" EXACT [UniProtKB:P11274] synonym: "D22S11" EXACT [UniProtKB:P11274] xref: EMBL:AB209991 xref: EMBL:AY536245 xref: EMBL:AY536247 xref: EMBL:AY536248 xref: EMBL:M15025 xref: EMBL:M64437 xref: EMBL:U07000 xref: EMBL:X02596 xref: EMBL:X14676 xref: EMBL:X52828 xref: EMBL:X52829 xref: EMBL:Y00661 xref: HGNC:HGNC:1014 xref: HGNC:HGNC:13609 xref: UniGene:Hs.517461 xref: UniGene:Hs.634378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006123 ! BCR_HUMAN relationship: codes_for CCO:B0055849 ! Q12843_HUMAN relationship: codes_for CCO:B0055850 ! Q12845_HUMAN relationship: codes_for CCO:B0056930 ! Q6QJE5_HUMAN relationship: codes_for CCO:B0056931 ! Q6QJE6_HUMAN relationship: codes_for CCO:B0056932 ! Q6QJE8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004157 name: BECN1_human def: "Beclin-1 gene" [UniProtKB:Q14457] synonym: "GT197" EXACT [UniProtKB:Q14457] xref: EMBL:AF077301 xref: EMBL:AF139131 xref: EMBL:BC010276 xref: EMBL:L38932 xref: HGNC:HGNC:1034 xref: UniGene:Hs.12272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005950 ! BECN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004158 name: BEGAIN_human def: "Brain-enriched guanylate kinase-associated protein gene" [UniProtKB:Q9BUH8] synonym: "KIAA1446" EXACT [UniProtKB:Q9BUH8] xref: EMBL:AB040879 xref: EMBL:AL390162 xref: EMBL:BC002607 xref: HGNC:HGNC:24163 xref: UniGene:Hs.211751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005626 ! BEGIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004159 name: BHLHB2_human def: "Class B basic helix-loop-helix protein 2 gene" [UniProtKB:O14503] synonym: "DEC1" EXACT [UniProtKB:O14503] synonym: "SHARP2" EXACT [UniProtKB:O14503] synonym: "STRA13" EXACT [UniProtKB:O14503] xref: EMBL:AB004066 xref: EMBL:AB043885 xref: EMBL:AF353634 xref: EMBL:AF353635 xref: EMBL:BC082238 xref: HGNC:HGNC:1046 xref: UniGene:Hs.171825 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005888 ! BHLH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004160 name: BID_human def: "BH3-interacting domain death agonist gene" [UniProtKB:P55957] xref: EMBL:AF042083 xref: EMBL:AF087891 xref: EMBL:AF250233 xref: EMBL:AY005151 xref: EMBL:AY309922 xref: EMBL:BC009197 xref: EMBL:BC022072 xref: EMBL:BC033634 xref: EMBL:BC036364 xref: EMBL:CR407603 xref: EMBL:CR456389 xref: HGNC:HGNC:1050 xref: UniGene:Hs.591054 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005422 ! BID_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004161 name: BIK_human def: "Bcl-2-interacting killer gene" [UniProtKB:Q13323] synonym: "NBK" EXACT [UniProtKB:Q13323] xref: EMBL:AF174421 xref: EMBL:AF174422 xref: EMBL:AF174423 xref: EMBL:AF174424 xref: EMBL:AL022237 xref: EMBL:AY245248 xref: EMBL:BC001599 xref: EMBL:BT006728 xref: EMBL:CR456390 xref: EMBL:U34584 xref: EMBL:U49730 xref: EMBL:X89986 xref: HGNC:HGNC:1051 xref: UniGene:Hs.475055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005421 ! BIK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004162 name: BCL2L11_human def: "Bcl-2-like protein 11 gene" [UniProtKB:O43521] synonym: "BIM" EXACT [UniProtKB:O43521] xref: EMBL:AB071195 xref: EMBL:AB071196 xref: EMBL:AB071197 xref: EMBL:AB071198 xref: EMBL:AB071199 xref: EMBL:AB071200 xref: EMBL:AC096670 xref: EMBL:AF032457 xref: EMBL:AF032458 xref: EMBL:AK290377 xref: EMBL:AK291269 xref: EMBL:AY305714 xref: EMBL:AY305715 xref: EMBL:AY352518 xref: EMBL:AY423441 xref: EMBL:AY423442 xref: EMBL:AY423443 xref: EMBL:AY428962 xref: EMBL:BC033694 xref: EMBL:CH471237 xref: EMBL:DQ849200 xref: EMBL:DQ849201 xref: EMBL:DQ849202 xref: HGNC:HGNC:994 xref: UniGene:Hs.469658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006003 ! BIM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004163 name: BIN1_human def: "Myc box-dependent-interacting protein 1 gene" [UniProtKB:O00499] synonym: "AMPHL" EXACT [UniProtKB:O00499] xref: EMBL:AF001383 xref: EMBL:AF004015 xref: EMBL:AF043898 xref: EMBL:AF043899 xref: EMBL:AF043900 xref: EMBL:AF043901 xref: EMBL:AF068914 xref: EMBL:AF068915 xref: EMBL:AF068916 xref: EMBL:AF068917 xref: EMBL:AF068918 xref: EMBL:AF070576 xref: EMBL:U68485 xref: EMBL:U83999 xref: EMBL:U84001 xref: EMBL:U84002 xref: EMBL:U84003 xref: EMBL:U84004 xref: EMBL:U87558 xref: HGNC:HGNC:1052 xref: UniGene:Hs.193163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001349 ! BIN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004164 name: BIN3_human def: "Bridging integrator 3 gene" [UniProtKB:Q9NQY0] xref: EMBL:AF271732 xref: EMBL:AK001289 xref: EMBL:AK023980 xref: EMBL:BC001223 xref: EMBL:BC009824 xref: HGNC:HGNC:1054 xref: UniGene:Hs.696034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002156 ! BIN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004165 name: BIRC2_human def: "Baculoviral IAP repeat-containing protein 2 gene" [UniProtKB:Q13490] synonym: "API1" EXACT [UniProtKB:Q13490] synonym: "IAP2" EXACT [UniProtKB:Q13490] synonym: "MIHB" EXACT [UniProtKB:Q13490] synonym: "RNF48" EXACT [UniProtKB:Q13490] xref: EMBL:BC016174 xref: EMBL:BC028578 xref: EMBL:DQ068066 xref: EMBL:L49431 xref: EMBL:U37547 xref: EMBL:U45879 xref: HGNC:HGNC:590 xref: UniGene:Hs.696238 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005671 ! BIRC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004166 name: BIRC5_human def: "Baculoviral IAP repeat-containing protein 5 gene" [UniProtKB:O15392] synonym: "API4" EXACT [UniProtKB:O15392] synonym: "IAP4" EXACT [UniProtKB:O15392] xref: EMBL:AB028869 xref: EMBL:AB154416 xref: EMBL:AC087645 xref: EMBL:AF077350 xref: EMBL:AK223428 xref: EMBL:AY795969 xref: EMBL:AY830084 xref: EMBL:AY927772 xref: EMBL:BC008718 xref: EMBL:BC034148 xref: EMBL:BC065497 xref: EMBL:CR541740 xref: EMBL:DQ310375 xref: EMBL:DQ310376 xref: EMBL:DQ310377 xref: EMBL:DQ310378 xref: EMBL:DQ310379 xref: EMBL:U75285 xref: HGNC:HGNC:593 xref: UniGene:Hs.514527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001377 ! BIRC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004167 name: BLOC1S1_human def: "Biogenesis of lysosome-related organelles complex 1 subunit 1 gene" [UniProtKB:P78537] synonym: "BLOS1" EXACT [UniProtKB:P78537] synonym: "GCN5L1" EXACT [UniProtKB:P78537] synonym: "RT14" EXACT [UniProtKB:P78537] xref: EMBL:D64007 xref: EMBL:S82447 xref: HGNC:HGNC:4200 xref: UniGene:Hs.94672 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006194 ! BL1S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004168 name: BLM_human def: "Bloom syndrome protein gene" [UniProtKB:P54132] synonym: "RECQ2" EXACT [UniProtKB:P54132] synonym: "RECQL3" EXACT [UniProtKB:P54132] xref: EMBL:AY886902 xref: EMBL:BC093622 xref: EMBL:BC101567 xref: EMBL:BC115030 xref: EMBL:BC115032 xref: EMBL:U39817 xref: HGNC:HGNC:1058 xref: UniGene:Hs.169348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005502 ! BLM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004169 name: BMCC1_human def: "BNIP2 motif-containing molecule at the C-terminal region 1 gene" [UniProtKB:Q58A63] synonym: "BNIPXL" EXACT [UniProtKB:Q58A63] synonym: "KIAA0367" EXACT [UniProtKB:Q58A63] xref: EMBL:AB002365 xref: EMBL:AB050197 xref: EMBL:AL161626 xref: EMBL:AL359314 xref: EMBL:AY439213 xref: EMBL:AY439214 xref: EMBL:BC022571 xref: UniGene:Hs.262857 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001842 ! BMCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004170 name: BMP2_human def: "Bone morphogenetic protein 2 precursor gene" [UniProtKB:P12643] synonym: "BMP2A" EXACT [UniProtKB:P12643] xref: EMBL:AF040249 xref: EMBL:AL035668 xref: EMBL:M22489 xref: HGNC:HGNC:1069 xref: UniGene:Hs.73853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001515 ! BMP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004171 name: BMP4_human def: "Bone morphogenetic protein 4 precursor gene" [UniProtKB:P12644] synonym: "BMP2B" EXACT [UniProtKB:P12644] synonym: "DVR4" EXACT [UniProtKB:P12644] xref: EMBL:BC020546 xref: EMBL:D30751 xref: EMBL:M22490 xref: EMBL:U43842 xref: HGNC:HGNC:1071 xref: UniGene:Hs.68879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001516 ! BMP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004172 name: BMP7_human def: "Bone morphogenetic protein 7 precursor gene" [UniProtKB:P18075] synonym: "OP1" EXACT [UniProtKB:P18075] xref: EMBL:AL122058 xref: EMBL:AL157414 xref: EMBL:BC008584 xref: EMBL:M60316 xref: EMBL:X51801 xref: HGNC:HGNC:1074 xref: UniGene:Hs.473163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001531 ! BMP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004173 name: BMPR2_human def: "Bone morphogenetic protein receptor type-2 precursor gene" [UniProtKB:Q13873] synonym: "PPH1" EXACT [UniProtKB:Q13873] xref: EMBL:BC052985 xref: EMBL:CH471063 xref: EMBL:D50516 xref: EMBL:U20165 xref: EMBL:U25110 xref: EMBL:Z48923 xref: HGNC:HGNC:1078 xref: UniGene:Hs.471119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001767 ! BMPR2_HUMAN relationship: codes_for CCO:B0030652 ! Q13161_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004174 name: BMPR1A_human def: "Bone morphogenetic protein receptor type-1A precursor gene" [UniProtKB:P36894] synonym: "ACVRLK3" EXACT [UniProtKB:P36894] synonym: "ALK3" EXACT [UniProtKB:P36894] xref: EMBL:BC028383 xref: EMBL:Z22535 xref: HGNC:HGNC:1076 xref: UniGene:Hs.524477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005437 ! BMR1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004175 name: BMX_human def: "Cytoplasmic tyrosine-protein kinase BMX gene" [UniProtKB:P51813] xref: EMBL:AC097625 xref: EMBL:AF045459 xref: EMBL:BC016652 xref: EMBL:CH471074 xref: EMBL:U08341 xref: EMBL:X83107 xref: HGNC:HGNC:1079 xref: UniGene:Hs.495731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005923 ! BMX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004176 name: BNIP3L_human def: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like gene" [UniProtKB:O60238] synonym: "BNIP3A" EXACT [UniProtKB:O60238] synonym: "BNIP3H" EXACT [UniProtKB:O60238] synonym: "NIX" EXACT [UniProtKB:O60238] xref: EMBL:AB004788 xref: EMBL:AF067396 xref: EMBL:AF079221 xref: EMBL:AF255051 xref: EMBL:AF452712 xref: EMBL:AF536326 xref: EMBL:BC001559 xref: EMBL:BC009603 xref: EMBL:BT019501 xref: HGNC:HGNC:1085 xref: UniGene:Hs.131226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005714 ! BNI3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004177 name: BNIP2_human def: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 gene" [UniProtKB:Q12982] synonym: "NIP2" EXACT [UniProtKB:Q12982] xref: EMBL:AY268590 xref: EMBL:BC002461 xref: EMBL:U15173 xref: HGNC:HGNC:1083 xref: UniGene:Hs.646490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005677 ! BNIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004178 name: BNIP3_human def: "BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 gene" [UniProtKB:Q12983] synonym: "NIP3" EXACT [UniProtKB:Q12983] xref: EMBL:AF002697 xref: EMBL:AL162274 xref: EMBL:AY886764 xref: EMBL:BC009342 xref: EMBL:BC021989 xref: EMBL:U15174 xref: HGNC:HGNC:1084 xref: UniGene:Hs.144873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005678 ! BNIP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004179 name: BOC_human def: "Brother of CDO precursor gene" [UniProtKB:Q9BWV1] synonym: "UNQ604/PRO1190" EXACT [UniProtKB:Q9BWV1] xref: EMBL:AC026329 xref: EMBL:AK074556 xref: EMBL:AK090455 xref: EMBL:AY027658 xref: EMBL:AY358328 xref: HGNC:HGNC:17173 xref: UniGene:Hs.591318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006259 ! BOC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004180 name: BOLL_human def: "Protein boule-like gene" [UniProtKB:Q8N9W6] synonym: "BOULE" EXACT [UniProtKB:Q8N9W6] xref: EMBL:AF272858 xref: EMBL:AK058099 xref: EMBL:AK093453 xref: EMBL:BC033674 xref: HGNC:HGNC:14273 xref: UniGene:Hs.169797 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001972 ! BOLL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004181 name: BORA_human def: "Protein aurora borealis gene" [UniProtKB:Q6PGQ7] synonym: "C13orf34" EXACT [UniProtKB:Q6PGQ7] xref: EMBL:AK026277 xref: EMBL:AL138695 xref: EMBL:BC007119 xref: EMBL:BC025367 xref: EMBL:BC044213 xref: EMBL:BC056876 xref: HGNC:HGNC:24724 xref: UniGene:Hs.705516 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001914 ! BORA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004182 name: CDCA8_human def: "Borealin gene" [UniProtKB:Q53HL2] synonym: "PESCRG3" EXACT [UniProtKB:Q53HL2] xref: EMBL:AK001330 xref: EMBL:AK022104 xref: EMBL:AK022606 xref: EMBL:AK222549 xref: EMBL:AK222568 xref: EMBL:AY508815 xref: EMBL:BC000703 xref: EMBL:BC001651 xref: EMBL:BC008079 xref: EMBL:BC016944 xref: EMBL:BG354581 xref: HGNC:HGNC:14629 xref: UniGene:Hs.702170 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001839 ! BOREA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004183 name: DST_human def: "Bullous pemphigoid antigen 1, isoforms 1/2/3/4/5/8 gene" [UniProtKB:Q03001] synonym: "BPAG1" EXACT [UniProtKB:Q03001] synonym: "DMH" EXACT [UniProtKB:Q03001] synonym: "DT" EXACT [UniProtKB:Q03001] synonym: "KIAA0728" EXACT [UniProtKB:Q03001] xref: EMBL:AB018271 xref: EMBL:AF400226 xref: EMBL:AK055189 xref: EMBL:AK094883 xref: EMBL:AK096713 xref: EMBL:AL096710 xref: EMBL:AL137008 xref: EMBL:AL512422 xref: EMBL:AL512448 xref: EMBL:AL590005 xref: EMBL:AY032900 xref: EMBL:AY032901 xref: EMBL:BC004912 xref: EMBL:BC016991 xref: EMBL:L11690 xref: EMBL:M22942 xref: EMBL:M63618 xref: EMBL:M69225 xref: EMBL:U04850 xref: EMBL:U31850 xref: EMBL:U31851 xref: EMBL:X58677 xref: HGNC:HGNC:1090 xref: UniGene:Hs.631992 xref: UniGene:Hs.669931 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001443 ! BPAEA_HUMAN relationship: codes_for CCO:B0001884 ! Q5TBT1_HUMAN relationship: codes_for CCO:B0001885 ! Q5TBT2_HUMAN relationship: codes_for CCO:B0002096 ! Q9BSP9_HUMAN relationship: codes_for CCO:B0017433 ! BPA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004184 name: BRAF_human def: "B-Raf proto-oncogene serine/threonine-protein kinase gene" [UniProtKB:P15056] synonym: "BRAF1" EXACT [UniProtKB:P15056] synonym: "RAFB1" EXACT [UniProtKB:P15056] xref: EMBL:AC006344 xref: EMBL:AC006347 xref: EMBL:BC101757 xref: EMBL:BC112079 xref: EMBL:M21001 xref: EMBL:M95712 xref: EMBL:X65187 xref: HGNC:HGNC:1097 xref: UniGene:Hs.550061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005913 ! BRAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004185 name: BRAP_human def: "BRCA1-associated protein gene" [UniProtKB:Q7Z569] synonym: "RNF52" EXACT [UniProtKB:Q7Z569] xref: EMBL:AF035620 xref: EMBL:AF035950 xref: EMBL:AY332222 xref: HGNC:HGNC:1099 xref: UniGene:Hs.577448 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005471 ! BRAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004186 name: BRCA1_human def: "Breast cancer type 1 susceptibility protein gene" [UniProtKB:P38398] synonym: "RNF53" EXACT [UniProtKB:P38398] xref: EMBL:AF005068 xref: EMBL:AY273801 xref: EMBL:L78833 xref: EMBL:U14680 xref: EMBL:U64805 xref: HGNC:HGNC:1100 xref: UniGene:Hs.194143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001598 ! BRCA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004187 name: BRCA2_human def: "Breast cancer type 2 susceptibility protein gene" [UniProtKB:P51587] synonym: "FACD" EXACT [UniProtKB:P51587] synonym: "FANCD1" EXACT [UniProtKB:P51587] xref: EMBL:AY436640 xref: EMBL:U43746 xref: EMBL:X95152 xref: EMBL:X95153 xref: EMBL:X95154 xref: EMBL:X95155 xref: EMBL:X95156 xref: EMBL:X95157 xref: EMBL:X95158 xref: EMBL:X95159 xref: EMBL:X95160 xref: EMBL:X95161 xref: EMBL:X95162 xref: EMBL:X95163 xref: EMBL:X95164 xref: EMBL:X95165 xref: EMBL:X95166 xref: EMBL:X95167 xref: EMBL:X95168 xref: EMBL:X95169 xref: EMBL:X95170 xref: EMBL:X95171 xref: EMBL:X95172 xref: EMBL:X95173 xref: EMBL:X95174 xref: EMBL:X95175 xref: EMBL:X95176 xref: EMBL:X95177 xref: EMBL:Z73359 xref: EMBL:Z74739 xref: HGNC:HGNC:1101 xref: UniGene:Hs.34012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001649 ! BRCA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004188 name: BRD4_human def: "Bromodomain-containing protein 4 gene" [UniProtKB:O60885] synonym: "HUNK1" EXACT [UniProtKB:O60885] xref: EMBL:AC004798 xref: EMBL:AF386649 xref: EMBL:AY166680 xref: EMBL:Y12059 xref: HGNC:HGNC:13575 xref: UniGene:Hs.187763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006311 ! BRD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004189 name: BRD7_human def: "Bromodomain-containing protein 7 gene" [UniProtKB:Q9NPI1] synonym: "BP75" EXACT [UniProtKB:Q9NPI1] synonym: "CELTIX1" EXACT [UniProtKB:Q9NPI1] xref: EMBL:AF152604 xref: EMBL:AF213969 xref: EMBL:AJ271881 xref: EMBL:AK027308 xref: EMBL:AK074613 xref: EMBL:BC001611 xref: EMBL:BC050728 xref: EMBL:BC094706 xref: HGNC:HGNC:14310 xref: UniGene:Hs.437894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005400 ! BRD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004190 name: BRE_human def: "Protein BRE gene" [UniProtKB:Q9NXR7] xref: EMBL:AF015767 xref: EMBL:AF420605 xref: EMBL:AK000097 xref: EMBL:AY438031 xref: EMBL:BC001251 xref: EMBL:L38616 xref: HGNC:HGNC:1106 xref: UniGene:Hs.11916 xref: UniGene:Hs.258314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005951 ! BRE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004191 name: BRMS1_human def: "Breast cancer metastasis-suppressor 1 gene" [UniProtKB:Q9HCU9] xref: EMBL:AF159141 xref: EMBL:AF281036 xref: EMBL:BC009834 xref: HGNC:HGNC:17262 xref: UniGene:Hs.100426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002147 ! BRMS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004192 name: BRSK1_human def: "BR serine/threonine-protein kinase 1 gene" [UniProtKB:Q8TDC3] synonym: "KIAA1811" EXACT [UniProtKB:Q8TDC3] synonym: "SAD1" EXACT [UniProtKB:Q8TDC3] xref: EMBL:AB058714 xref: EMBL:AF479826 xref: EMBL:AF479827 xref: EMBL:AL831945 xref: EMBL:AL834275 xref: EMBL:AY458602 xref: EMBL:AY505124 xref: EMBL:BC016681 xref: HGNC:HGNC:18994 xref: UniGene:Hs.182081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001992 ! BRSK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004193 name: BTBD2_human def: "BTB/POZ domain-containing protein 2 gene" [UniProtKB:Q9BX70] xref: EMBL:AC004678 xref: EMBL:AC005306 xref: EMBL:AF355797 xref: EMBL:AK000393 xref: EMBL:AK027481 xref: EMBL:AL360275 xref: EMBL:BC000564 xref: EMBL:BC008035 xref: EMBL:BC053986 xref: EMBL:BC094820 xref: EMBL:CR457230 xref: HGNC:HGNC:15504 xref: UniGene:Hs.465543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005933 ! BTBD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004194 name: BTBD10_human def: "BTB/POZ domain-containing protein 10 gene" [UniProtKB:Q9BSF8] xref: EMBL:AL832981 xref: EMBL:AY221959 xref: EMBL:BC005071 xref: HGNC:HGNC:21445 xref: UniGene:Hs.332382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006271 ! BTBDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004195 name: BTC_human def: "Probetacellulin precursor gene" [UniProtKB:P35070] xref: EMBL:BC011618 xref: EMBL:S55606 xref: HGNC:HGNC:1121 xref: UniGene:Hs.591704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001590 ! BTC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004196 name: BTG3_human def: "Protein BTG3 gene" [UniProtKB:Q14201] synonym: "ANA" EXACT [UniProtKB:Q14201] synonym: "TOB5" EXACT [UniProtKB:Q14201] xref: EMBL:BC011957 xref: EMBL:D64110 xref: HGNC:HGNC:1132 xref: UniGene:Hs.473420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001778 ! BTG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004197 name: BTG4_human def: "Protein BTG4 gene" [UniProtKB:Q9NY30] synonym: "PC3B" EXACT [UniProtKB:Q9NY30] xref: EMBL:AJ271351 xref: HGNC:HGNC:13862 xref: UniGene:Hs.128180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002174 ! BTG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004198 name: BUB1B_human def: "Mitotic checkpoint serine/threonine-protein kinase BUB1 beta gene" [UniProtKB:O60566] synonym: "BUBR1" EXACT [UniProtKB:O60566] synonym: "MAD3L" EXACT [UniProtKB:O60566] xref: EMBL:AF035933 xref: EMBL:AF046079 xref: EMBL:AF046918 xref: EMBL:AF053306 xref: EMBL:AF068760 xref: EMBL:AF107297 xref: EMBL:AF310192 xref: EMBL:AF310193 xref: EMBL:AF310194 xref: EMBL:AF310195 xref: EMBL:AF310196 xref: EMBL:AF310197 xref: EMBL:AF310198 xref: EMBL:AF310199 xref: EMBL:AF310200 xref: EMBL:AF310201 xref: EMBL:AF310202 xref: EMBL:AF310203 xref: EMBL:AF310204 xref: EMBL:AF310205 xref: EMBL:AF310206 xref: EMBL:AF310207 xref: EMBL:AF310208 xref: EMBL:AF310209 xref: EMBL:AF310210 xref: EMBL:AF310211 xref: EMBL:AF310212 xref: EMBL:AF310213 xref: EMBL:AF310214 xref: HGNC:HGNC:1149 xref: UniGene:Hs.631699 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001411 ! BUB1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004199 name: BUB1_human def: "Mitotic checkpoint serine/threonine-protein kinase BUB1 gene" [UniProtKB:O43683] synonym: "BUB1L" EXACT [UniProtKB:O43683] xref: EMBL:AF011387 xref: EMBL:AF043294 xref: EMBL:AF046078 xref: EMBL:AF047471 xref: EMBL:AF053305 xref: EMBL:AF139349 xref: EMBL:AF139350 xref: EMBL:AF139351 xref: EMBL:AF139352 xref: EMBL:AF139353 xref: EMBL:AF139354 xref: EMBL:AF139355 xref: EMBL:AF139356 xref: EMBL:AF139357 xref: EMBL:AF139358 xref: EMBL:AF139359 xref: EMBL:AF139360 xref: EMBL:AF139361 xref: EMBL:AF139362 xref: EMBL:AF139363 xref: EMBL:BC028201 xref: HGNC:HGNC:1148 xref: UniGene:Hs.469649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001395 ! BUB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004200 name: BUB3_human def: "Mitotic checkpoint protein BUB3 gene" [UniProtKB:O43684] xref: EMBL:AF047472 xref: EMBL:AF047473 xref: EMBL:AF053304 xref: EMBL:AF081496 xref: EMBL:BC005138 xref: EMBL:BC022438 xref: HGNC:HGNC:1151 xref: UniGene:Hs.418533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001396 ! BUB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004201 name: C1orf123_human def: "UPF0587 protein C1orf123 gene" [UniProtKB:Q9NWV4] xref: EMBL:AK000587 xref: EMBL:AL606760 xref: EMBL:BC010908 xref: EMBL:CR457246 xref: HGNC:HGNC:26059 xref: UniGene:Hs.525391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006314 ! CA123_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004202 name: CAB39_human def: "Calcium-binding protein 39 gene" [UniProtKB:Q9Y376] synonym: "CGI-66" EXACT [UniProtKB:Q9Y376] synonym: "MO25" EXACT [UniProtKB:Q9Y376] xref: EMBL:AF113536 xref: EMBL:AF151824 xref: EMBL:BC020570 xref: HGNC:HGNC:20292 xref: UniGene:Hs.632536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005876 ! CAB39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004203 name: CABLES1_human def: "CDK5 and ABL1 enzyme substrate 1 gene" [UniProtKB:Q8TDN4] synonym: "CABLES" EXACT [UniProtKB:Q8TDN4] xref: EMBL:AC011731 xref: EMBL:AC105247 xref: EMBL:AF348525 xref: EMBL:AK093243 xref: EMBL:BC004124 xref: EMBL:BC037218 xref: HGNC:HGNC:25097 xref: UniGene:Hs.11108 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001994 ! CABL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004204 name: CABLES2_human def: "CDK5 and ABL1 enzyme substrate 2 gene" [UniProtKB:Q9BTV7] synonym: "C20orf150" EXACT [UniProtKB:Q9BTV7] xref: EMBL:AL121832 xref: EMBL:BC003122 xref: HGNC:HGNC:16143 xref: UniGene:Hs.301040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002097 ! CABL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004205 name: CACNA1A_human def: "Voltage-dependent P/Q-type calcium channel subunit alpha-1A gene" [UniProtKB:O00555] synonym: "CACH4" EXACT [UniProtKB:O00555] synonym: "CACN3" EXACT [UniProtKB:O00555] synonym: "CACNL1A4" EXACT [UniProtKB:O00555] xref: EMBL:AC005305 xref: EMBL:AC008540 xref: EMBL:AC011446 xref: EMBL:AC022436 xref: EMBL:AC026805 xref: EMBL:AC098781 xref: EMBL:AC124224 xref: EMBL:AF004883 xref: EMBL:AF004884 xref: EMBL:S76537 xref: EMBL:U06702 xref: EMBL:U79663 xref: EMBL:U79664 xref: EMBL:U79665 xref: EMBL:U79666 xref: EMBL:U79667 xref: EMBL:U79668 xref: EMBL:X99897 xref: EMBL:Z80114 xref: EMBL:Z80115 xref: HGNC:HGNC:1388 xref: UniGene:Hs.501632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006044 ! CAC1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004206 name: CACNA1C_human def: "Voltage-dependent L-type calcium channel subunit alpha-1C gene" [UniProtKB:Q13936] synonym: "CACH2" EXACT [UniProtKB:Q13936] synonym: "CACN2" EXACT [UniProtKB:Q13936] synonym: "CACNL1A1" EXACT [UniProtKB:Q13936] synonym: "CCHL1A1" EXACT [UniProtKB:Q13936] xref: EMBL:AC005293 xref: EMBL:AC005342 xref: EMBL:AC005344 xref: EMBL:AC005414 xref: EMBL:AC005866 xref: EMBL:AC006051 xref: EMBL:AC007618 xref: EMBL:AC092471 xref: EMBL:AF465484 xref: EMBL:AJ224873 xref: EMBL:AY604867 xref: EMBL:AY830711 xref: EMBL:AY830712 xref: EMBL:AY830713 xref: EMBL:BC146846 xref: EMBL:L04568 xref: EMBL:L04569 xref: EMBL:L29529 xref: EMBL:L29530 xref: EMBL:L29531 xref: EMBL:L29532 xref: EMBL:L29533 xref: EMBL:L29534 xref: EMBL:L29535 xref: EMBL:L29536 xref: EMBL:L29537 xref: EMBL:L29538 xref: EMBL:L29539 xref: EMBL:M57971 xref: EMBL:M57972 xref: EMBL:M61130 xref: EMBL:M91370 xref: EMBL:M92269 xref: EMBL:M92270 xref: EMBL:M92271 xref: EMBL:M92272 xref: EMBL:M92273 xref: EMBL:M92274 xref: EMBL:M92275 xref: EMBL:Z26256 xref: EMBL:Z26257 xref: EMBL:Z26258 xref: EMBL:Z26259 xref: EMBL:Z26260 xref: EMBL:Z26261 xref: EMBL:Z26262 xref: EMBL:Z26263 xref: EMBL:Z26264 xref: EMBL:Z26265 xref: EMBL:Z26266 xref: EMBL:Z26267 xref: EMBL:Z26268 xref: EMBL:Z26269 xref: EMBL:Z26271 xref: EMBL:Z26272 xref: EMBL:Z26273 xref: EMBL:Z26274 xref: EMBL:Z26275 xref: EMBL:Z26276 xref: EMBL:Z26277 xref: EMBL:Z26278 xref: EMBL:Z26279 xref: EMBL:Z26280 xref: EMBL:Z26281 xref: EMBL:Z26282 xref: EMBL:Z26283 xref: EMBL:Z26284 xref: EMBL:Z26286 xref: EMBL:Z26287 xref: EMBL:Z26288 xref: EMBL:Z26294 xref: EMBL:Z26295 xref: EMBL:Z26308 xref: EMBL:Z34809 xref: EMBL:Z34810 xref: EMBL:Z34811 xref: EMBL:Z34812 xref: EMBL:Z34813 xref: EMBL:Z34814 xref: EMBL:Z34815 xref: EMBL:Z34816 xref: EMBL:Z34817 xref: EMBL:Z34818 xref: EMBL:Z34819 xref: EMBL:Z34820 xref: EMBL:Z34821 xref: EMBL:Z34822 xref: EMBL:Z74996 xref: HGNC:HGNC:1390 xref: UniGene:Hs.118262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005692 ! CAC1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004207 name: CACNB4_human def: "Voltage-dependent L-type calcium channel subunit beta-4 gene" [UniProtKB:O00305] synonym: "CACNLB4" EXACT [UniProtKB:O00305] xref: EMBL:AF038852 xref: EMBL:AY054985 xref: EMBL:BC075049 xref: EMBL:U95020 xref: HGNC:HGNC:1404 xref: UniGene:Hs.614033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006176 ! CACB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004208 name: CDH10_human def: "Cadherin-10 precursor gene" [UniProtKB:Q9Y6N8] xref: EMBL:AB035303 xref: EMBL:AF039747 xref: HGNC:HGNC:1749 xref: UniGene:Hs.92489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006177 ! CAD10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004209 name: CDH1_human def: "Epithelial cadherin precursor gene" [UniProtKB:P12830] synonym: "CDHE" EXACT [UniProtKB:P12830] synonym: "UVO" EXACT [UniProtKB:P12830] xref: EMBL:D49685 xref: EMBL:DQ090940 xref: EMBL:L08599 xref: EMBL:L34545 xref: EMBL:S72397 xref: EMBL:S72491 xref: EMBL:S72492 xref: EMBL:X12790 xref: EMBL:X52279 xref: EMBL:Z13009 xref: EMBL:Z18923 xref: EMBL:Z35402 xref: EMBL:Z35403 xref: EMBL:Z35404 xref: EMBL:Z35405 xref: EMBL:Z35406 xref: EMBL:Z35407 xref: EMBL:Z35408 xref: EMBL:Z35409 xref: EMBL:Z35410 xref: EMBL:Z35411 xref: EMBL:Z35412 xref: EMBL:Z35413 xref: EMBL:Z35414 xref: EMBL:Z35415 xref: HGNC:HGNC:1748 xref: UniGene:Hs.461086 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005581 ! CADH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004210 name: CADM1_human def: "Cell adhesion molecule 1 precursor gene" [UniProtKB:Q9BY67] synonym: "IGSF4" EXACT [UniProtKB:Q9BY67] synonym: "NECL2" EXACT [UniProtKB:Q9BY67] synonym: "SYNCAM" EXACT [UniProtKB:Q9BY67] synonym: "TSLC1" EXACT [UniProtKB:Q9BY67] xref: EMBL:AB094146 xref: EMBL:AF132811 xref: EMBL:AK075502 xref: HGNC:HGNC:5951 xref: UniGene:Hs.370510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002110 ! CADM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004211 name: CADM4_human def: "Cell adhesion molecule 4 precursor gene" [UniProtKB:Q8NFZ8] synonym: "IGSF4C" EXACT [UniProtKB:Q8NFZ8] synonym: "NECL4" EXACT [UniProtKB:Q8NFZ8] synonym: "TSLL2" EXACT [UniProtKB:Q8NFZ8] xref: EMBL:AC005525 xref: EMBL:AF363368 xref: HGNC:HGNC:30825 xref: UniGene:Hs.370984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001983 ! CADM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004212 name: CHAF1A_human def: "Chromatin assembly factor 1 subunit A gene" [UniProtKB:Q13111] synonym: "CAF" EXACT [UniProtKB:Q13111] synonym: "CAF1P150" EXACT [UniProtKB:Q13111] xref: EMBL:AF190465 xref: EMBL:BC052620 xref: EMBL:U20979 xref: HGNC:HGNC:1910 xref: UniGene:Hs.79018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001742 ! CAF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004213 name: CHAF1B_human def: "Chromatin assembly factor 1 subunit B gene" [UniProtKB:Q13112] synonym: "CAF1A" EXACT [UniProtKB:Q13112] synonym: "CAF1P60" EXACT [UniProtKB:Q13112] synonym: "MPHOSPH7" EXACT [UniProtKB:Q13112] synonym: "MPP7" EXACT [UniProtKB:Q13112] xref: EMBL:AP000694 xref: EMBL:AP001725 xref: EMBL:BC021218 xref: EMBL:U20980 xref: EMBL:X98262 xref: HGNC:HGNC:1911 xref: UniGene:Hs.75238 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001743 ! CAF1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004214 name: CALM1_human def: "Calmodulin gene" [UniProtKB:P62158] synonym: "CALM" EXACT [UniProtKB:P62158] synonym: "CAM" EXACT [UniProtKB:P62158] synonym: "CAM1" EXACT [UniProtKB:P62158] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001690 ! CALM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004215 name: CALM2_human def: "Calmodulin gene" [UniProtKB:P62158] synonym: "CAM2" EXACT [UniProtKB:P62158] synonym: "CAMB" EXACT [UniProtKB:P62158] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001690 ! CALM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004216 name: CALM3_human def: "Calmodulin gene" [UniProtKB:P62158] synonym: "CALML2" EXACT [UniProtKB:P62158] synonym: "CAM3" EXACT [UniProtKB:P62158] synonym: "CAMC" EXACT [UniProtKB:P62158] synonym: "CAMIII" EXACT [UniProtKB:P62158] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001690 ! CALM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004217 name: CALR_human def: "Calreticulin precursor gene" [UniProtKB:P27797] synonym: "CRTC" EXACT [UniProtKB:P27797] xref: EMBL:AD000092 xref: EMBL:AY047586 xref: EMBL:BC002500 xref: EMBL:BC007911 xref: EMBL:BC020493 xref: EMBL:M32294 xref: EMBL:M84739 xref: HGNC:HGNC:1455 xref: UniGene:Hs.515162 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001563 ! CALR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004218 name: CAND1_human def: "Cullin-associated NEDD8-dissociated protein 1 gene" [UniProtKB:Q86VP6] synonym: "KIAA0829" EXACT [UniProtKB:Q86VP6] synonym: "TIP120" EXACT [UniProtKB:Q86VP6] synonym: "TIP120A" EXACT [UniProtKB:Q86VP6] xref: EMBL:AB020636 xref: EMBL:AF157326 xref: EMBL:AK027404 xref: EMBL:AK027783 xref: EMBL:AL133560 xref: EMBL:AL136810 xref: EMBL:AL833880 xref: EMBL:BC004232 xref: EMBL:BC026220 xref: EMBL:BC050341 xref: HGNC:HGNC:30688 xref: UniGene:Hs.546407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005355 ! CAND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004219 name: CAPZB_human def: "F-actin-capping protein subunit beta gene" [UniProtKB:P47756] xref: EMBL:AL035413 xref: EMBL:AL359199 xref: EMBL:AL445163 xref: EMBL:BC024601 xref: EMBL:BT019470 xref: EMBL:BT019471 xref: EMBL:U03271 xref: HGNC:HGNC:1491 xref: UniGene:Hs.432760 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006125 ! CAPZB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004220 name: CASC5_human def: "Protein CASC5 gene" [UniProtKB:Q8NG31] synonym: "KIAA1570" EXACT [UniProtKB:Q8NG31] xref: EMBL:AB022190 xref: EMBL:AB046790 xref: EMBL:AF173994 xref: EMBL:AF248041 xref: EMBL:AF461041 xref: HGNC:HGNC:24054 xref: UniGene:Hs.181855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006064 ! CASC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004221 name: NEDD9_human def: "Enhancer of filamentation 1 gene" [UniProtKB:Q14511] synonym: "CASL" EXACT [UniProtKB:Q14511] synonym: "CASS2" EXACT [UniProtKB:Q14511] xref: EMBL:AL136139 xref: EMBL:AL139807 xref: EMBL:BC040207 xref: EMBL:CH471087 xref: EMBL:L43821 xref: EMBL:U64317 xref: HGNC:HGNC:7733 xref: UniGene:Hs.699288 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001782 ! CASL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004222 name: CASP9_human def: "Caspase-9 precursor gene" [UniProtKB:P55211] synonym: "MCH6" EXACT [UniProtKB:P55211] xref: EMBL:AB015653 xref: EMBL:AB019205 xref: EMBL:AB020979 xref: EMBL:AF093130 xref: EMBL:AF110376 xref: EMBL:AL512883 xref: EMBL:AY214168 xref: EMBL:BC002452 xref: EMBL:BC006463 xref: EMBL:U56390 xref: EMBL:U60521 xref: HGNC:HGNC:1511 xref: UniGene:Hs.329502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005903 ! CASP9_HUMAN relationship: codes_for CCO:B0056471 ! Q5JRU8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004223 name: CTSB_human def: "Cathepsin B precursor gene" [UniProtKB:P07858] synonym: "CPSB" EXACT [UniProtKB:P07858] xref: EMBL:BC010240 xref: EMBL:BC095408 xref: EMBL:L16510 xref: EMBL:M13230 xref: EMBL:M14221 xref: HGNC:HGNC:2527 xref: UniGene:Hs.520898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006345 ! CATB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004224 name: CAV1_human def: "Caveolin-1 gene" [UniProtKB:Q03135] synonym: "CAV" EXACT [UniProtKB:Q03135] xref: EMBL:AF095591 xref: EMBL:AF095592 xref: EMBL:AF095593 xref: EMBL:AF125348 xref: EMBL:AJ133269 xref: EMBL:BC009685 xref: EMBL:BC082246 xref: EMBL:BT007143 xref: EMBL:Z18951 xref: HGNC:HGNC:1527 xref: UniGene:Hs.74034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005456 ! CAV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004225 name: CAV2_human def: "Caveolin-2 gene" [UniProtKB:P51636] xref: EMBL:AF035752 xref: EMBL:AJ133269 xref: EMBL:AJ242718 xref: EMBL:BC005256 xref: EMBL:BT007051 xref: HGNC:HGNC:1528 xref: UniGene:Hs.212332 xref: UniGene:Hs.603096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005462 ! CAV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004226 name: CAPZA2_human def: "F-actin-capping protein subunit alpha-2 gene" [UniProtKB:P47755] xref: EMBL:AC002543 xref: EMBL:BC005338 xref: EMBL:BT006735 xref: EMBL:U03269 xref: EMBL:U03851 xref: HGNC:HGNC:1490 xref: UniGene:Hs.695918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005582 ! CAZA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004227 name: CBLB_human def: "E3 ubiquitin-protein ligase CBL-B gene" [UniProtKB:Q13191] synonym: "Nbla00127" EXACT [UniProtKB:Q13191] synonym: "RNF56" EXACT [UniProtKB:Q13191] xref: EMBL:AB075490 xref: EMBL:BC032851 xref: EMBL:BX537484 xref: EMBL:U26710 xref: EMBL:U26711 xref: EMBL:U26712 xref: HGNC:HGNC:1542 xref: UniGene:Hs.430589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005819 ! CBLB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004228 name: CBL_human def: "E3 ubiquitin-protein ligase CBL gene" [UniProtKB:P22681] synonym: "CBL2" EXACT [UniProtKB:P22681] synonym: "RNF55" EXACT [UniProtKB:P22681] xref: EMBL:BC132733 xref: EMBL:X57110 xref: HGNC:HGNC:1541 xref: UniGene:Hs.504096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005611 ! CBL_HUMAN relationship: codes_for CCO:B0053745 ! A3KMP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004229 name: CPE_human def: "Carboxypeptidase E precursor gene" [UniProtKB:P16870] xref: EMBL:AB006898 xref: EMBL:BC033866 xref: EMBL:BC053612 xref: EMBL:X51405 xref: HGNC:HGNC:2303 xref: UniGene:Hs.699184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006081 ! CBPE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004230 name: CREBBP_human def: "CREB-binding protein gene" [UniProtKB:Q92793] synonym: "CBP" EXACT [UniProtKB:Q92793] xref: EMBL:U47741 xref: EMBL:U85962 xref: EMBL:U89354 xref: EMBL:U89355 xref: HGNC:HGNC:2348 xref: UniGene:Hs.459759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005339 ! CBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004231 name: CBX1_human def: "Chromobox protein homolog 1 gene" [UniProtKB:P83916] synonym: "CBX" EXACT [UniProtKB:P83916] xref: EMBL:BC002609 xref: EMBL:BC021302 xref: EMBL:U35451 xref: HGNC:HGNC:1551 xref: UniGene:Hs.77254 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006126 ! CBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004232 name: CBX5_human def: "Chromobox protein homolog 5 gene" [UniProtKB:P45973] synonym: "HP1A" EXACT [UniProtKB:P45973] xref: EMBL:BC006821 xref: EMBL:L07515 xref: EMBL:S62077 xref: EMBL:U26311 xref: HGNC:HGNC:1555 xref: UniGene:Hs.632724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005317 ! CBX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004233 name: CCDC101_human def: "SAGA-associated factor 29 homolog gene" [UniProtKB:Q96ES7] synonym: "SGF29" EXACT [UniProtKB:Q96ES7] xref: EMBL:AK057008 xref: EMBL:BC011981 xref: HGNC:HGNC:25156 xref: UniGene:Hs.655476 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058208 ! SGF29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004234 name: CDC14A_human def: "Dual specificity protein phosphatase CDC14A gene" [UniProtKB:Q9UNH5] xref: EMBL:AF000367 xref: EMBL:AF064102 xref: EMBL:AF064103 xref: EMBL:AF122013 xref: EMBL:AY623111 xref: EMBL:BC038979 xref: HGNC:HGNC:1718 xref: UniGene:Hs.127411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002233 ! CC14A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004235 name: CDC45L_human def: "CDC45-related protein gene" [UniProtKB:O75419] synonym: "CDC45L2" EXACT [UniProtKB:O75419] synonym: "UNQ374/PRO710" EXACT [UniProtKB:O75419] xref: EMBL:AF053074 xref: EMBL:AF062495 xref: EMBL:AF081535 xref: EMBL:AJ223728 xref: EMBL:AY358971 xref: EMBL:AY572790 xref: EMBL:BC006232 xref: EMBL:BC010022 xref: EMBL:BT006792 xref: HGNC:HGNC:1739 xref: UniGene:Hs.474217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001426 ! CC45L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004236 name: CCAR1_human def: "Cell division cycle and apoptosis regulator protein 1 gene" [UniProtKB:Q8IX12] synonym: "CARP1" EXACT [UniProtKB:Q8IX12] synonym: "DIS" EXACT [UniProtKB:Q8IX12] xref: EMBL:AF465616 xref: EMBL:AK000741 xref: EMBL:AK001452 xref: EMBL:AK001701 xref: EMBL:AK023438 xref: EMBL:AL391539 xref: EMBL:AL513534 xref: EMBL:AY249140 xref: EMBL:BC026036 xref: EMBL:BC108682 xref: HGNC:HGNC:24236 xref: UniGene:Hs.49853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001950 ! CCAR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004239 name: CCDC99_human def: "Coiled-coil domain-containing protein 99 gene" [UniProtKB:Q96EA4] xref: EMBL:AF269167 xref: EMBL:AK000371 xref: EMBL:AK074227 xref: EMBL:AY517557 xref: EMBL:BC012568 xref: HGNC:HGNC:26010 xref: UniGene:Hs.368710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006191 ! CCD99_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004240 name: CCDC5_human def: "Coiled-coil domain-containing protein 5 gene" [UniProtKB:Q96CS2] synonym: "HEIC" EXACT [UniProtKB:Q96CS2] xref: EMBL:AK097403 xref: EMBL:AY360137 xref: EMBL:BC005958 xref: EMBL:BC014003 xref: HGNC:HGNC:25174 xref: UniGene:Hs.436617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002034 ! CCDC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004241 name: CCL18_human def: "C-C motif chemokine 18 precursor gene" [UniProtKB:P55774] synonym: "AMAC1" EXACT [UniProtKB:P55774] synonym: "DCCK1" EXACT [UniProtKB:P55774] synonym: "MIP4" EXACT [UniProtKB:P55774] synonym: "PARC" EXACT [UniProtKB:P55774] synonym: "SCYA18" EXACT [UniProtKB:P55774] xref: EMBL:AB000221 xref: EMBL:AB012113 xref: EMBL:AF082212 xref: EMBL:AF082213 xref: EMBL:AF082214 xref: EMBL:AF111198 xref: EMBL:BC069700 xref: EMBL:BC096124 xref: EMBL:BC096125 xref: EMBL:BC096126 xref: EMBL:BC096127 xref: EMBL:CR407660 xref: EMBL:Y13710 xref: HGNC:HGNC:10616 xref: UniGene:Hs.143961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006087 ! CCL18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004242 name: CCNA1_human def: "Cyclin-A1 gene" [UniProtKB:P78396] xref: EMBL:AL359767 xref: EMBL:BC036346 xref: EMBL:BT019577 xref: EMBL:CH471075 xref: EMBL:U66838 xref: EMBL:U97680 xref: HGNC:HGNC:1577 xref: UniGene:Hs.417050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001701 ! CCNA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004243 name: CCNA2_human def: "Cyclin-A2 gene" [UniProtKB:P20248] synonym: "CCN1" EXACT [UniProtKB:P20248] synonym: "CCNA" EXACT [UniProtKB:P20248] xref: EMBL:AC079341 xref: EMBL:AF518006 xref: EMBL:BC104783 xref: EMBL:BC104787 xref: EMBL:CR407692 xref: EMBL:X51688 xref: EMBL:X68303 xref: HGNC:HGNC:1578 xref: UniGene:Hs.58974 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001538 ! CCNA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004244 name: CCNB1_human def: "G2/mitotic-specific cyclin-B1 gene" [UniProtKB:P14635] synonym: "CCNB" EXACT [UniProtKB:P14635] xref: EMBL:AY338491 xref: EMBL:BC006510 xref: EMBL:M25753 xref: HGNC:HGNC:1579 xref: UniGene:Hs.23960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001519 ! CCNB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004245 name: CCNB2_human def: "G2/mitotic-specific cyclin-B2 gene" [UniProtKB:O95067] xref: EMBL:AB020981 xref: EMBL:AF002822 xref: EMBL:AL080146 xref: EMBL:AY864066 xref: EMBL:BC105086 xref: EMBL:BC105112 xref: EMBL:CR533527 xref: HGNC:HGNC:1580 xref: UniGene:Hs.194698 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001446 ! CCNB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004246 name: CCNB3_human def: "G2/mitotic-specific cyclin-B3 gene" [UniProtKB:Q8WWL7] synonym: "CYCB3" EXACT [UniProtKB:Q8WWL7] xref: EMBL:AJ314764 xref: EMBL:AJ314765 xref: EMBL:AJ314766 xref: EMBL:AJ416458 xref: EMBL:AL137550 xref: EMBL:AL591367 xref: EMBL:BX323840 xref: EMBL:CH471180 xref: HGNC:HGNC:18709 xref: UniGene:Hs.130310 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002007 ! CCNB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004247 name: CCNC_human def: "Cyclin-C gene" [UniProtKB:P24863] xref: EMBL:AL137784 xref: EMBL:M74091 xref: EMBL:U40728 xref: EMBL:U40729 xref: EMBL:U40730 xref: EMBL:U40731 xref: EMBL:U40732 xref: EMBL:U40733 xref: EMBL:U40734 xref: EMBL:U40735 xref: EMBL:U40736 xref: EMBL:U40737 xref: EMBL:U40738 xref: EMBL:U40739 xref: HGNC:HGNC:1581 xref: UniGene:Hs.430646 xref: UniGene:Hs.633351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001553 ! CCNC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004248 name: CCND1_human def: "G1/S-specific cyclin-D1 gene" [UniProtKB:P24385] synonym: "BCL1" EXACT [UniProtKB:P24385] synonym: "PRAD1" EXACT [UniProtKB:P24385] xref: EMBL:AF511593 xref: EMBL:BC000076 xref: EMBL:BC001501 xref: EMBL:BC014078 xref: EMBL:BC023620 xref: EMBL:BC025302 xref: EMBL:BT019845 xref: EMBL:L09054 xref: EMBL:M64349 xref: EMBL:M73554 xref: EMBL:M74092 xref: EMBL:X59798 xref: EMBL:Z23022 xref: HGNC:HGNC:1582 xref: UniGene:Hs.523852 xref: UniGene:Hs.702537 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001551 ! CCND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004249 name: CCND2_human def: "G1/S-specific cyclin-D2 gene" [UniProtKB:P30279] xref: EMBL:AF518005 xref: EMBL:BC010958 xref: EMBL:BC089384 xref: EMBL:BT019847 xref: EMBL:D13639 xref: EMBL:M88080 xref: EMBL:M88081 xref: EMBL:M88082 xref: EMBL:M88083 xref: EMBL:M90813 xref: EMBL:X68452 xref: HGNC:HGNC:1583 xref: UniGene:Hs.376071 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001573 ! CCND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004250 name: CCND3_human def: "G1/S-specific cyclin-D3 gene" [UniProtKB:P30281] xref: EMBL:AF517525 xref: EMBL:AL160163 xref: EMBL:BC011616 xref: EMBL:M88084 xref: EMBL:M88085 xref: EMBL:M88086 xref: EMBL:M88087 xref: EMBL:M90814 xref: EMBL:M92287 xref: HGNC:HGNC:1585 xref: UniGene:Hs.534307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001574 ! CCND3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004251 name: CCNE1_human def: "G1/S-specific cyclin-E1 gene" [UniProtKB:P24864] synonym: "CCNE" EXACT [UniProtKB:P24864] xref: EMBL:AF518727 xref: EMBL:BC035498 xref: EMBL:M73812 xref: EMBL:M74093 xref: EMBL:U40787 xref: EMBL:U40788 xref: EMBL:X95406 xref: HGNC:HGNC:1589 xref: UniGene:Hs.244723 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001554 ! CCNE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004252 name: CCNE2_human def: "G1/S-specific cyclin-E2 gene" [UniProtKB:O96020] xref: EMBL:AF091433 xref: EMBL:AF102778 xref: EMBL:AF106690 xref: EMBL:AF112857 xref: EMBL:AY850195 xref: EMBL:BC007015 xref: EMBL:BC020729 xref: EMBL:CH471060 xref: HGNC:HGNC:1590 xref: UniGene:Hs.567387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001460 ! CCNE2_HUMAN relationship: codes_for CCO:B0001935 ! Q7Z774_HUMAN relationship: codes_for CCO:B0002001 ! Q8WUE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004253 name: CCNF_human def: "G2/mitotic-specific cyclin-F gene" [UniProtKB:P41002] xref: EMBL:BC012349 xref: EMBL:U17105 xref: EMBL:Z36714 xref: HGNC:HGNC:1591 xref: UniGene:Hs.1973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001602 ! CCNF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004254 name: CCNG1_human def: "Cyclin-G1 gene" [UniProtKB:P51959] synonym: "CCNG" EXACT [UniProtKB:P51959] synonym: "CYCG1" EXACT [UniProtKB:P51959] xref: EMBL:AY791292 xref: EMBL:BC000196 xref: EMBL:BC007093 xref: EMBL:BT007134 xref: EMBL:D78341 xref: EMBL:D86077 xref: EMBL:L49504 xref: EMBL:U47413 xref: EMBL:U53328 xref: EMBL:X77794 xref: HGNC:HGNC:1592 xref: UniGene:Hs.79101 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001656 ! CCNG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004255 name: CCNG2_human def: "Cyclin-G2 gene" [UniProtKB:Q16589] xref: EMBL:AF549495 xref: EMBL:BT019503 xref: EMBL:L49506 xref: EMBL:U47414 xref: HGNC:HGNC:1593 xref: UniGene:Hs.13291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001821 ! CCNG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004256 name: CCNH_human def: "Cyclin-H gene" [UniProtKB:P51946] xref: EMBL:AF477979 xref: EMBL:BC005280 xref: EMBL:BC016705 xref: EMBL:BC016823 xref: EMBL:BC022351 xref: EMBL:U11791 xref: EMBL:U12685 xref: HGNC:HGNC:1594 xref: UniGene:Hs.292524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001652 ! CCNH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004260 name: CCNK_human def: "Cyclin-K gene" [UniProtKB:O75909] synonym: "CPR4" EXACT [UniProtKB:O75909] xref: EMBL:AF060515 xref: EMBL:AF270825 xref: EMBL:AF270826 xref: EMBL:AF270827 xref: EMBL:AF270828 xref: EMBL:AF270829 xref: EMBL:AF270830 xref: EMBL:AF270831 xref: EMBL:AF270832 xref: EMBL:AF542236 xref: EMBL:BC015935 xref: EMBL:BT006950 xref: HGNC:HGNC:1596 xref: UniGene:Hs.705475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001439 ! CCNK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004261 name: CCNL1_human def: "Cyclin-L1 gene" [UniProtKB:Q9UK58] synonym: "BM-001" EXACT [UniProtKB:Q9UK58] synonym: "UNQ530/PRO1073" EXACT [UniProtKB:Q9UK58] xref: EMBL:AF180920 xref: EMBL:AF208843 xref: EMBL:AF367476 xref: EMBL:AF367477 xref: EMBL:AY034790 xref: EMBL:AY358663 xref: EMBL:BC007081 xref: EMBL:BC038394 xref: EMBL:BC067812 xref: HGNC:HGNC:20569 xref: UniGene:Hs.4859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002218 ! CCNL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004262 name: CCNT1_human def: "Cyclin-T1 gene" [UniProtKB:O60563] xref: EMBL:AF045161 xref: EMBL:AF048730 xref: HGNC:HGNC:1599 xref: UniGene:Hs.279906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001410 ! CCNT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004263 name: CCNT2_human def: "Cyclin-T2 gene" [UniProtKB:O60583] xref: EMBL:AC016725 xref: EMBL:AF048731 xref: EMBL:AF048732 xref: EMBL:AY865621 xref: HGNC:HGNC:1600 xref: UniGene:Hs.591241 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001412 ! CCNT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004265 name: CCPG1_human def: "Cell cycle progression protein 1 gene" [UniProtKB:Q9ULG6] synonym: "CCP8" EXACT [UniProtKB:Q9ULG6] synonym: "CPR8" EXACT [UniProtKB:Q9ULG6] synonym: "KIAA1254" EXACT [UniProtKB:Q9ULG6] xref: EMBL:AB033080 xref: EMBL:AF011794 xref: EMBL:AF212228 xref: EMBL:AK022459 xref: EMBL:BC015203 xref: EMBL:BC029398 xref: EMBL:BC034914 xref: EMBL:BC039871 xref: EMBL:CH471082 xref: HGNC:HGNC:24227 xref: UniGene:Hs.612814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002225 ! CCPG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004266 name: CCRK_human def: "Cell cycle-related kinase gene" [UniProtKB:Q8IZL9] synonym: "CDCH" EXACT [UniProtKB:Q8IZL9] xref: EMBL:AF547664 xref: EMBL:AL353572 xref: EMBL:AY904367 xref: EMBL:BC002655 xref: HGNC:HGNC:21420 xref: UniGene:Hs.522274 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001955 ! CCRK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004268 name: CDC123_human def: "Cell division cycle protein 123 homolog gene" [UniProtKB:O75794] synonym: "C10orf7" EXACT [UniProtKB:O75794] synonym: "D123" EXACT [UniProtKB:O75794] xref: EMBL:AL512770 xref: EMBL:BC001600 xref: EMBL:BC009598 xref: EMBL:CR456966 xref: EMBL:D14878 xref: EMBL:U27112 xref: HGNC:HGNC:16827 xref: UniGene:Hs.412842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001435 ! CD123_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004269 name: ALCAM_human def: "CD166 antigen precursor gene" [UniProtKB:Q13740] synonym: "MEMD" EXACT [UniProtKB:Q13740] xref: EMBL:DQ486139 xref: EMBL:DQ486140 xref: EMBL:L38608 xref: EMBL:Y10183 xref: HGNC:HGNC:400 xref: UniGene:Hs.591293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005455 ! CD166_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004270 name: CD28_human def: "T-cell-specific surface glycoprotein CD28 precursor gene" [UniProtKB:P10747] xref: EMBL:AC125238 xref: EMBL:AF222341 xref: EMBL:AF222342 xref: EMBL:AF222343 xref: EMBL:AF411057 xref: EMBL:AJ295273 xref: EMBL:AJ517504 xref: EMBL:BC093698 xref: EMBL:BC112085 xref: EMBL:CH471063 xref: EMBL:EF064755 xref: EMBL:J02988 xref: EMBL:M37812 xref: EMBL:M37813 xref: EMBL:M37814 xref: EMBL:M37815 xref: HGNC:HGNC:1653 xref: UniGene:Hs.591629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001508 ! CD28_HUMAN relationship: codes_for CCO:B0001927 ! Q70WG0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004271 name: CDKN2A_human def: "Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 gene" [UniProtKB:P42771] synonym: "CDKN2" EXACT [UniProtKB:P42771] synonym: "MTS1" EXACT [UniProtKB:P42771] xref: EMBL:AB060808 xref: EMBL:AF115544 xref: EMBL:AF527803 xref: EMBL:AL449423 xref: EMBL:BC015960 xref: EMBL:BC021998 xref: EMBL:BT007020 xref: EMBL:L27211 xref: EMBL:S69804 xref: EMBL:S69822 xref: EMBL:S69824 xref: EMBL:S78535 xref: EMBL:U12818 xref: EMBL:U12819 xref: EMBL:U12820 xref: EMBL:U26727 xref: EMBL:U38945 xref: EMBL:X94154 xref: HGNC:HGNC:1787 xref: UniGene:Hs.512599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001615 ! CD2A1_HUMAN relationship: codes_for CCO:B0001966 ! CD2A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004272 name: CD2AP_human def: "CD2-associated protein gene" [UniProtKB:Q9Y5K6] xref: EMBL:AF146277 xref: EMBL:AF164377 xref: EMBL:AL050105 xref: EMBL:AL355353 xref: EMBL:AL358178 xref: EMBL:BC069444 xref: EMBL:CH471081 xref: HGNC:HGNC:14258 xref: UniGene:Hs.485518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002257 ! CD2AP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004273 name: CDC2L1_human def: "PITSLRE serine/threonine-protein kinase CDC2L1 gene" [UniProtKB:P21127] synonym: "PITSLREA" EXACT [UniProtKB:P21127] synonym: "PK58" EXACT [UniProtKB:P21127] xref: EMBL:AF067512 xref: EMBL:AF067513 xref: EMBL:AF067514 xref: EMBL:AF067515 xref: EMBL:AF067516 xref: EMBL:AF067517 xref: EMBL:AF080678 xref: EMBL:AF080679 xref: EMBL:AF080680 xref: EMBL:AF080681 xref: EMBL:AF080682 xref: EMBL:AF080683 xref: EMBL:AF080685 xref: EMBL:AF080686 xref: EMBL:AF080687 xref: EMBL:AF080688 xref: EMBL:AF092429 xref: EMBL:AF092430 xref: EMBL:AF174497 xref: EMBL:BC033069 xref: EMBL:M37712 xref: EMBL:M88553 xref: EMBL:M88554 xref: EMBL:M88555 xref: EMBL:M88558 xref: EMBL:M88559 xref: EMBL:M88560 xref: EMBL:M88561 xref: EMBL:M88562 xref: EMBL:M88563 xref: EMBL:U04815 xref: EMBL:U04816 xref: EMBL:U04817 xref: EMBL:U04818 xref: EMBL:U04824 xref: HGNC:HGNC:1729 xref: UniGene:Hs.651228 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001540 ! CD2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004274 name: CDC2L2_human def: "PITSLRE serine/threonine-protein kinase CDC2L2 gene" [UniProtKB:Q9UQ88] synonym: "CDC2L3" EXACT [UniProtKB:Q9UQ88] synonym: "PITSLREB" EXACT [UniProtKB:Q9UQ88] xref: EMBL:AF067518 xref: EMBL:AF067519 xref: EMBL:AF067520 xref: EMBL:AF067521 xref: EMBL:AF067522 xref: EMBL:AF067523 xref: EMBL:AF067524 xref: EMBL:AF067525 xref: EMBL:AF067526 xref: EMBL:AF067527 xref: EMBL:AF067528 xref: EMBL:AF067529 xref: EMBL:AF080689 xref: EMBL:AF080690 xref: EMBL:AF080691 xref: EMBL:AF080692 xref: EMBL:AF080693 xref: EMBL:AF080694 xref: EMBL:AF080695 xref: EMBL:AF080696 xref: EMBL:AF080697 xref: EMBL:AF092427 xref: EMBL:AF092428 xref: EMBL:AF105714 xref: EMBL:AL031282 xref: EMBL:U04819 xref: EMBL:U07704 xref: EMBL:U07705 xref: HGNC:HGNC:1730 xref: UniGene:Hs.651228 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002241 ! CD2L2_HUMAN relationship: codes_for CCO:B0015090 ! Q5QPR4_HUMAN relationship: codes_for CCO:B0015092 ! Q5QPR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004275 name: CDC2L5_human def: "Cell division cycle 2-like protein kinase 5 gene" [UniProtKB:Q14004] synonym: "CDC2L" EXACT [UniProtKB:Q14004] synonym: "CHED" EXACT [UniProtKB:Q14004] synonym: "KIAA1791" EXACT [UniProtKB:Q14004] xref: EMBL:AB058694 xref: EMBL:AC006023 xref: EMBL:AC072061 xref: EMBL:AJ297709 xref: EMBL:AJ297710 xref: EMBL:AY679523 xref: EMBL:M80629 xref: HGNC:HGNC:1733 xref: UniGene:Hs.233552 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001771 ! CD2L5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004276 name: CDC2L6_human def: "Cell division cycle 2-like protein kinase 6 gene" [UniProtKB:Q9BWU1] synonym: "CDK11" EXACT [UniProtKB:Q9BWU1] synonym: "KIAA1028" EXACT [UniProtKB:Q9BWU1] xref: EMBL:AB028951 xref: EMBL:AL512430 xref: EMBL:AL603914 xref: EMBL:AY028424 xref: EMBL:BC024247 xref: EMBL:BC037289 xref: EMBL:Z84480 xref: HGNC:HGNC:19338 xref: UniGene:Hs.584867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005788 ! CD2L6_HUMAN relationship: codes_for CCO:B0023207 ! Q5JQZ9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004277 name: PTPRC_human def: "Leukocyte common antigen precursor gene" [UniProtKB:P08575] synonym: "CD45" EXACT [UniProtKB:P08575] xref: EMBL:M23466 xref: EMBL:M23467 xref: EMBL:M23468 xref: EMBL:M23469 xref: EMBL:M23470 xref: EMBL:M23471 xref: EMBL:M23472 xref: EMBL:M23473 xref: EMBL:M23474 xref: EMBL:M23475 xref: EMBL:M23476 xref: EMBL:M23477 xref: EMBL:M23478 xref: EMBL:M23479 xref: EMBL:M23480 xref: EMBL:M23481 xref: EMBL:M23482 xref: EMBL:M23483 xref: EMBL:M23484 xref: EMBL:M23485 xref: EMBL:M23486 xref: EMBL:M23487 xref: EMBL:M23488 xref: EMBL:M23489 xref: EMBL:M23490 xref: EMBL:M23491 xref: EMBL:M23492 xref: EMBL:M23496 xref: EMBL:Y00062 xref: EMBL:Y00638 xref: HGNC:HGNC:9666 xref: UniGene:Hs.654514 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001499 ! CD45_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004278 name: CD4_human def: "T-cell surface glycoprotein CD4 precursor gene" [UniProtKB:P01730] xref: EMBL:BC025782 xref: EMBL:BT019791 xref: EMBL:BT019811 xref: EMBL:DQ012936 xref: EMBL:M12807 xref: EMBL:M35160 xref: EMBL:U47924 xref: HGNC:HGNC:1678 xref: UniGene:Hs.631659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005740 ! CD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004279 name: CD59_human def: "CD59 glycoprotein precursor gene" [UniProtKB:P13987] synonym: "MIC11" EXACT [UniProtKB:P13987] synonym: "MIN1" EXACT [UniProtKB:P13987] synonym: "MIN2" EXACT [UniProtKB:P13987] synonym: "MIN3" EXACT [UniProtKB:P13987] synonym: "MSK21" EXACT [UniProtKB:P13987] xref: EMBL:BC001506 xref: EMBL:BT007104 xref: EMBL:M27909 xref: EMBL:M34671 xref: EMBL:M84345 xref: EMBL:M84346 xref: EMBL:M84348 xref: EMBL:M84349 xref: EMBL:M95708 xref: EMBL:X16447 xref: EMBL:X17198 xref: EMBL:Z14113 xref: EMBL:Z14114 xref: EMBL:Z14115 xref: HGNC:HGNC:1689 xref: UniGene:Hs.278573 xref: UniGene:Hs.703109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005875 ! CD59_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004280 name: CDK5R1_human def: "Cyclin-dependent kinase 5 activator 1 precursor gene" [UniProtKB:Q15078] synonym: "CDK5R" EXACT [UniProtKB:Q15078] synonym: "NCK5A" EXACT [UniProtKB:Q15078] xref: EMBL:AY376350 xref: EMBL:BC020580 xref: EMBL:X80343 xref: HGNC:HGNC:1775 xref: UniGene:Hs.500015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001802 ! CD5R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004281 name: CDK5R2_human def: "Cyclin-dependent kinase 5 activator 2 precursor gene" [UniProtKB:Q13319] synonym: "NCK5AI" EXACT [UniProtKB:Q13319] xref: EMBL:AC097468 xref: EMBL:DQ307839 xref: EMBL:U34051 xref: HGNC:HGNC:1776 xref: UniGene:Hs.158460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001751 ! CD5R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004282 name: CD81_human def: "CD81 antigen gene" [UniProtKB:P60033] synonym: "TAPA1" EXACT [UniProtKB:P60033] synonym: "TSPAN28" EXACT [UniProtKB:P60033] xref: EMBL:BC002978 xref: EMBL:BC093047 xref: EMBL:BT019507 xref: EMBL:BT019508 xref: EMBL:EF064749 xref: EMBL:M33680 xref: HGNC:HGNC:1701 xref: UniGene:Hs.54457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006262 ! CD81_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004283 name: CDC16_human def: "Cell division cycle protein 16 homolog gene" [UniProtKB:Q13042] synonym: "ANAPC6" EXACT [UniProtKB:Q13042] xref: EMBL:AF164598 xref: EMBL:AL160396 xref: EMBL:AY599074 xref: EMBL:BC010875 xref: EMBL:BC017244 xref: EMBL:CH471085 xref: EMBL:U18291 xref: HGNC:HGNC:1720 xref: UniGene:Hs.374127 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001739 ! CDC16_HUMAN relationship: codes_for CCO:B0017386 ! Q7Z651_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004284 name: CDC20_human def: "Cell division cycle protein 20 homolog gene" [UniProtKB:Q12834] xref: EMBL:AF099644 xref: EMBL:AL139289 xref: EMBL:BC000624 xref: EMBL:BC001088 xref: EMBL:BC006272 xref: EMBL:BC009425 xref: EMBL:BC009426 xref: EMBL:BC010044 xref: EMBL:BC012803 xref: EMBL:BC012827 xref: EMBL:BC013303 xref: EMBL:BC015998 xref: EMBL:BC024257 xref: EMBL:BC031294 xref: EMBL:BC110321 xref: EMBL:BT007388 xref: EMBL:DQ473545 xref: EMBL:U05340 xref: HGNC:HGNC:1723 xref: UniGene:Hs.524947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001733 ! CDC20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004285 name: CDC23_human def: "Cell division cycle protein 23 homolog gene" [UniProtKB:Q9UJX2] synonym: "ANAPC8" EXACT [UniProtKB:Q9UJX2] xref: EMBL:AB011472 xref: EMBL:AF053977 xref: EMBL:AF191341 xref: EMBL:AY603103 xref: EMBL:BC005258 xref: EMBL:BC010944 xref: EMBL:BC017713 xref: EMBL:BT009810 xref: HGNC:HGNC:1724 xref: UniGene:Hs.153546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002212 ! CDC23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004286 name: CDC26_human def: "Anaphase-promoting complex subunit CDC26 gene" [UniProtKB:Q8NHZ8] synonym: "C9orf17" EXACT [UniProtKB:Q8NHZ8] xref: EMBL:AF503918 xref: EMBL:AL449305 xref: EMBL:BC042534 xref: EMBL:BC066300 xref: HGNC:HGNC:17839 xref: UniGene:Hs.530284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001986 ! CDC26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004287 name: CDC27_human def: "Cell division cycle protein 27 homolog gene" [UniProtKB:P30260] synonym: "D0S1430E" EXACT [UniProtKB:P30260] synonym: "D17S978E" EXACT [UniProtKB:P30260] xref: EMBL:AY518321 xref: EMBL:BC011656 xref: EMBL:S78234 xref: EMBL:U00001 xref: HGNC:HGNC:1728 xref: UniGene:Hs.463295 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001572 ! CDC27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004288 name: CDC2_human def: "Cell division control protein 2 homolog gene" [UniProtKB:P06493] xref: EMBL:AF512554 xref: EMBL:BC014563 xref: EMBL:BT007004 xref: EMBL:D88357 xref: EMBL:X05360 xref: EMBL:Y00272 xref: HGNC:HGNC:1722 xref: UniGene:Hs.334562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001493 ! CDC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004289 name: CDC37_human def: "Hsp90 co-chaperone Cdc37 gene" [UniProtKB:Q16543] synonym: "CDC37A" EXACT [UniProtKB:Q16543] xref: EMBL:AY864824 xref: EMBL:BC000083 xref: EMBL:BC008793 xref: EMBL:U43077 xref: EMBL:U63131 xref: HGNC:HGNC:1735 xref: UniGene:Hs.160958 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001819 ! CDC37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004290 name: CDC42_human def: "Cell division control protein 42 homolog precursor gene" [UniProtKB:P60953] xref: EMBL:AF498962 xref: EMBL:AF498963 xref: EMBL:AL031281 xref: EMBL:AL121734 xref: EMBL:AL121735 xref: EMBL:AY673602 xref: EMBL:BC002711 xref: EMBL:BC003682 xref: EMBL:BC018266 xref: EMBL:M35543 xref: EMBL:M57298 xref: HGNC:HGNC:1736 xref: UniGene:Hs.690198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005338 ! CDC42_HUMAN relationship: codes_for CCO:B0056512 ! Q5JYX0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004291 name: CDC5L_human def: "Cell division cycle 5-like protein gene" [UniProtKB:Q99459] synonym: "KIAA0432" EXACT [UniProtKB:Q99459] synonym: "PCDC5RP" EXACT [UniProtKB:Q99459] xref: EMBL:AB007892 xref: EMBL:AL133262 xref: EMBL:AL353588 xref: EMBL:AY518540 xref: EMBL:BC001568 xref: EMBL:D85423 xref: EMBL:U86753 xref: HGNC:HGNC:1743 xref: UniGene:Hs.485471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002065 ! CDC5L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004292 name: CDC6_human def: "Cell division control protein 6 homolog gene" [UniProtKB:Q99741] synonym: "CDC18L" EXACT [UniProtKB:Q99741] xref: EMBL:AF022109 xref: EMBL:AY150310 xref: EMBL:BC025232 xref: EMBL:U77949 xref: HGNC:HGNC:1744 xref: UniGene:Hs.405958 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002087 ! CDC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004293 name: CDC73_human def: "Parafibromin gene" [UniProtKB:Q6P1J9] synonym: "C1orf28" EXACT [UniProtKB:Q6P1J9] synonym: "HRPT2" EXACT [UniProtKB:Q6P1J9] xref: EMBL:AF312865 xref: EMBL:AK026969 xref: EMBL:AL139133 xref: EMBL:AL390863 xref: EMBL:BC007325 xref: EMBL:BC014351 xref: EMBL:BC065037 xref: EMBL:CH471067 xref: HGNC:HGNC:16783 xref: UniGene:Hs.576497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001911 ! CDC73_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004294 name: CDC7_human def: "Cell division cycle 7-related protein kinase gene" [UniProtKB:O00311] synonym: "CDC7L1" EXACT [UniProtKB:O00311] xref: EMBL:AB003698 xref: EMBL:AF005209 xref: EMBL:AF015592 xref: EMBL:AL355871 xref: EMBL:AY312583 xref: EMBL:AY585721 xref: EMBL:BC110526 xref: EMBL:BC110527 xref: EMBL:BC111044 xref: HGNC:HGNC:1745 xref: UniGene:Hs.533573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001346 ! CDC7_HUMAN relationship: codes_for CCO:B0018116 ! Q6JSD6_HUMAN relationship: codes_for CCO:B0041934 ! B1AMW7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004295 name: CDCA2_human def: "Cell division cycle-associated protein 2 gene" [UniProtKB:Q69YH5] xref: EMBL:AK098670 xref: EMBL:AL833396 xref: EMBL:AL833627 xref: EMBL:BC036214 xref: EMBL:BC063651 xref: EMBL:BC085609 xref: EMBL:BC104450 xref: EMBL:BC104451 xref: EMBL:BG354575 xref: HGNC:HGNC:14623 xref: UniGene:Hs.33366 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001905 ! CDCA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004296 name: CDCA3_human def: "Cell division cycle-associated protein 3 gene" [UniProtKB:Q99618] synonym: "C8" EXACT [UniProtKB:Q99618] synonym: "GRCC8" EXACT [UniProtKB:Q99618] synonym: "TOME1" EXACT [UniProtKB:Q99618] xref: EMBL:BC002551 xref: EMBL:BC036512 xref: EMBL:BG354576 xref: EMBL:U47924 xref: HGNC:HGNC:14624 xref: UniGene:Hs.524216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002076 ! CDCA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004297 name: CDCA5_human def: "Sororin gene" [UniProtKB:Q96FF9] xref: EMBL:BC011000 xref: EMBL:BG354578 xref: HGNC:HGNC:14626 xref: UniGene:Hs.434886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002038 ! CDCA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004298 name: CDK10_human def: "Cell division protein kinase 10 gene" [UniProtKB:Q15131] xref: EMBL:AJ010341 xref: EMBL:AJ010342 xref: EMBL:AJ010343 xref: EMBL:AJ010344 xref: EMBL:AM392903 xref: EMBL:AM393177 xref: EMBL:AM393204 xref: EMBL:BC017342 xref: EMBL:BC025301 xref: EMBL:L33264 xref: EMBL:X78342 xref: HGNC:HGNC:1770 xref: UniGene:Hs.699177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001803 ! CDK10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004299 name: CDK2_human def: "Cell division protein kinase 2 gene" [UniProtKB:P24941] xref: EMBL:AF512553 xref: EMBL:BC003065 xref: EMBL:BT006821 xref: EMBL:M68520 xref: EMBL:X61622 xref: EMBL:X62071 xref: HGNC:HGNC:1771 xref: UniGene:Hs.19192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001555 ! CDK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004300 name: CDK3_human def: "Cell division protein kinase 3 gene" [UniProtKB:Q00526] xref: EMBL:AY789470 xref: EMBL:X66357 xref: HGNC:HGNC:1772 xref: UniGene:Hs.593566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001707 ! CDK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004301 name: CDK4_human def: "Cell division protein kinase 4 gene" [UniProtKB:P11802] xref: EMBL:AF507942 xref: EMBL:BC003644 xref: EMBL:BC005864 xref: EMBL:BC010153 xref: EMBL:M14505 xref: EMBL:S67448 xref: EMBL:U37022 xref: EMBL:U81031 xref: EMBL:Z48970 xref: HGNC:HGNC:1773 xref: UniGene:Hs.95577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001512 ! CDK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004302 name: CDK5_human def: "Cell division protein kinase 5 gene" [UniProtKB:Q00535] xref: EMBL:AY049778 xref: EMBL:BC005115 xref: EMBL:BT006680 xref: EMBL:X66364 xref: HGNC:HGNC:1774 xref: UniGene:Hs.647078 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001709 ! CDK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004303 name: CDK6_human def: "Cell division protein kinase 6 gene" [UniProtKB:Q00534] xref: EMBL:AC000065 xref: EMBL:AC004011 xref: EMBL:AC004128 xref: EMBL:AY128534 xref: EMBL:BC052264 xref: EMBL:X66365 xref: HGNC:HGNC:1777 xref: UniGene:Hs.119882 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001708 ! CDK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004304 name: CDK7_human def: "Cell division protein kinase 7 gene" [UniProtKB:P50613] synonym: "MO15" EXACT [UniProtKB:P50613] xref: EMBL:AY130859 xref: EMBL:BC000834 xref: EMBL:BC005298 xref: EMBL:L20320 xref: EMBL:X77303 xref: EMBL:X77743 xref: EMBL:X79193 xref: EMBL:Y13120 xref: HGNC:HGNC:1778 xref: UniGene:Hs.184298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001644 ! CDK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004305 name: CDK8_human def: "Cell division protein kinase 8 gene" [UniProtKB:P49336] xref: EMBL:AL159159 xref: EMBL:AL590108 xref: EMBL:BC069634 xref: EMBL:BC104492 xref: EMBL:BC105950 xref: EMBL:BC107601 xref: EMBL:CH471075 xref: EMBL:X85753 xref: HGNC:HGNC:1779 xref: UniGene:Hs.382306 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001627 ! CDK8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004306 name: CDK9_human def: "Cell division protein kinase 9 gene" [UniProtKB:P50750] synonym: "CDC2L4" EXACT [UniProtKB:P50750] xref: EMBL:AF255306 xref: EMBL:AF517840 xref: EMBL:AL162586 xref: EMBL:BC001968 xref: EMBL:BT019903 xref: EMBL:L25676 xref: EMBL:X80230 xref: HGNC:HGNC:1780 xref: UniGene:Hs.150423 xref: UniGene:Hs.557646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001647 ! CDK9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004307 name: CDK2AP1_human def: "Cyclin-dependent kinase 2-associated protein 1 gene" [UniProtKB:O14519] synonym: "CDKAP1" EXACT [UniProtKB:O14519] synonym: "DOC1" EXACT [UniProtKB:O14519] xref: EMBL:AB006077 xref: EMBL:AF006484 xref: EMBL:BC034717 xref: HGNC:HGNC:14002 xref: UniGene:Hs.433201 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001355 ! CDKA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004308 name: CDKN3_human def: "Cyclin-dependent kinase inhibitor 3 gene" [UniProtKB:Q16667] synonym: "CDI1" EXACT [UniProtKB:Q16667] synonym: "CIP2" EXACT [UniProtKB:Q16667] synonym: "KAP" EXACT [UniProtKB:Q16667] xref: EMBL:AF213033 xref: EMBL:AF213036 xref: EMBL:AF213038 xref: EMBL:AF213039 xref: EMBL:AF213041 xref: EMBL:AF213042 xref: EMBL:AF213046 xref: EMBL:AF213047 xref: EMBL:AF213053 xref: EMBL:AY194117 xref: EMBL:L25876 xref: EMBL:L27711 xref: EMBL:U02681 xref: HGNC:HGNC:1791 xref: UniGene:Hs.84113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001823 ! CDKN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004309 name: CDKN1A_human def: "Cyclin-dependent kinase inhibitor 1 gene" [UniProtKB:P38936] synonym: "CAP20" EXACT [UniProtKB:P38936] synonym: "CDKN1" EXACT [UniProtKB:P38936] synonym: "CIP1" EXACT [UniProtKB:P38936] synonym: "MDA6" EXACT [UniProtKB:P38936] synonym: "PIC1" EXACT [UniProtKB:P38936] synonym: "SDI1" EXACT [UniProtKB:P38936] synonym: "WAF1" EXACT [UniProtKB:P38936] xref: EMBL:AF497972 xref: EMBL:BC000275 xref: EMBL:BC000312 xref: EMBL:BC001935 xref: EMBL:BC013967 xref: EMBL:L25610 xref: EMBL:L26165 xref: EMBL:L47232 xref: EMBL:L47233 xref: EMBL:S67388 xref: EMBL:U03106 xref: EMBL:U09579 xref: EMBL:Z85996 xref: HGNC:HGNC:1784 xref: UniGene:Hs.370771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001599 ! CDN1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004310 name: CDKN1B_human def: "Cyclin-dependent kinase inhibitor 1B gene" [UniProtKB:P46527] synonym: "KIP1" EXACT [UniProtKB:P46527] xref: EMBL:AF480891 xref: EMBL:BC001971 xref: EMBL:EF474465 xref: EMBL:S76986 xref: EMBL:S76988 xref: EMBL:U10906 xref: HGNC:HGNC:1785 xref: UniGene:Hs.238990 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001343 ! A7KMP4_HUMAN relationship: codes_for CCO:B0001624 ! CDN1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004311 name: CDKN1C_human def: "Cyclin-dependent kinase inhibitor 1C gene" [UniProtKB:P49918] synonym: "KIP2" EXACT [UniProtKB:P49918] xref: EMBL:AC013791 xref: EMBL:BC067842 xref: EMBL:D64137 xref: EMBL:EU570054 xref: EMBL:U22398 xref: EMBL:U48869 xref: HGNC:HGNC:1786 xref: UniGene:Hs.106070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001333 ! A6NK88_HUMAN relationship: codes_for CCO:B0001640 ! CDN1C_HUMAN relationship: codes_for CCO:B0043819 ! B2D1N3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004312 name: CDKN2B_human def: "Cyclin-dependent kinase 4 inhibitor B gene" [UniProtKB:P42772] synonym: "MTS2" EXACT [UniProtKB:P42772] xref: EMBL:AF513858 xref: EMBL:AL449423 xref: EMBL:BC014469 xref: EMBL:CR536529 xref: EMBL:L36844 xref: EMBL:S69805 xref: EMBL:U17075 xref: HGNC:HGNC:1788 xref: UniGene:Hs.72901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001616 ! CDN2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004313 name: CDKN2C_human def: "Cyclin-dependent kinase 4 inhibitor C gene" [UniProtKB:P42773] synonym: "CDKN6" EXACT [UniProtKB:P42773] xref: EMBL:AF041248 xref: EMBL:AF041249 xref: EMBL:AF041250 xref: EMBL:AY094608 xref: EMBL:BC000598 xref: EMBL:BC005041 xref: EMBL:BC016173 xref: EMBL:U17074 xref: HGNC:HGNC:1789 xref: UniGene:Hs.525324 xref: UniGene:Hs.699587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001617 ! CDN2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004314 name: CDKN2D_human def: "Cyclin-dependent kinase 4 inhibitor D gene" [UniProtKB:P55273] xref: EMBL:AF044171 xref: EMBL:AF061327 xref: EMBL:AF518878 xref: EMBL:BC001822 xref: EMBL:CR542158 xref: EMBL:U20498 xref: EMBL:U40343 xref: EMBL:U49399 xref: HGNC:HGNC:1790 xref: UniGene:Hs.435051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001675 ! CDN2D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004315 name: CDT1_human def: "DNA replication factor Cdt1 gene" [UniProtKB:Q9H211] xref: EMBL:AB053172 xref: EMBL:AF070552 xref: EMBL:AF321125 xref: EMBL:BC000137 xref: EMBL:BC008676 xref: EMBL:BC008860 xref: EMBL:BC009410 xref: EMBL:BC014202 xref: EMBL:BC049205 xref: HGNC:HGNC:24576 xref: UniGene:Hs.122908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002126 ! CDT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004316 name: CEP110_human def: "Centrosomal protein of 110 kDa gene" [UniProtKB:O43303] synonym: "CP110" EXACT [UniProtKB:O43303] synonym: "KIAA0419" EXACT [UniProtKB:O43303] xref: EMBL:AB007879 xref: EMBL:AC003108 xref: EMBL:AC012621 xref: EMBL:AF083322 xref: EMBL:AF513978 xref: EMBL:AK074079 xref: EMBL:AL137068 xref: EMBL:AY651261 xref: EMBL:BC002932 xref: EMBL:BC036654 xref: EMBL:BC089415 xref: EMBL:BX640927 xref: EMBL:CR749255 xref: HGNC:HGNC:1858 xref: UniGene:Hs.279912 xref: UniGene:Hs.653263 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001389 ! CE110_HUMAN relationship: codes_for CCO:B0041260 ! CP110_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004317 name: CEBPB_human def: "CCAAT/enhancer-binding protein beta gene" [UniProtKB:P17676] synonym: "PP9092" EXACT [UniProtKB:P17676] synonym: "TCF5" EXACT [UniProtKB:P17676] xref: EMBL:AF289608 xref: EMBL:AL161937 xref: EMBL:AY193834 xref: EMBL:BC007538 xref: EMBL:BC021931 xref: EMBL:X52560 xref: HGNC:HGNC:1834 xref: UniGene:Hs.517106 xref: UniGene:Hs.688479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005514 ! CEBPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004318 name: CEBPG_human def: "CCAAT/enhancer-binding protein gamma gene" [UniProtKB:P53567] xref: EMBL:BC007582 xref: EMBL:BC013128 xref: EMBL:BT019819 xref: EMBL:BT019820 xref: EMBL:U20240 xref: HGNC:HGNC:1837 xref: UniGene:Hs.429666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005324 ! CEBPG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004319 name: CUGBP1_human def: "CUG-BP- and ETR-3-like factor 1 gene" [UniProtKB:Q92879] synonym: "BRUNOL2" EXACT [UniProtKB:Q92879] synonym: "CELF1" EXACT [UniProtKB:Q92879] synonym: "CUGBP" EXACT [UniProtKB:Q92879] synonym: "NAB50" EXACT [UniProtKB:Q92879] xref: EMBL:AB210019 xref: EMBL:AF248648 xref: EMBL:AF267533 xref: EMBL:AF267534 xref: EMBL:AJ007988 xref: EMBL:BC031079 xref: EMBL:U63289 xref: HGNC:HGNC:2549 xref: UniGene:Hs.632137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006265 ! CELF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004320 name: CELSR3_human def: "Cadherin EGF LAG seven-pass G-type receptor 3 precursor gene" [UniProtKB:Q9NYQ7] synonym: "CDHF11" EXACT [UniProtKB:Q9NYQ7] synonym: "EGFL1" EXACT [UniProtKB:Q9NYQ7] synonym: "FMI1" EXACT [UniProtKB:Q9NYQ7] synonym: "KIAA0812" EXACT [UniProtKB:Q9NYQ7] synonym: "MEGF2" EXACT [UniProtKB:Q9NYQ7] xref: EMBL:AB011536 xref: EMBL:AF231023 xref: HGNC:HGNC:3230 xref: UniGene:Hs.631926 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005546 ! CELR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004321 name: CENTD2_human def: "Centaurin-delta-2 gene" [UniProtKB:Q96P48] synonym: "ARAP1" EXACT [UniProtKB:Q96P48] synonym: "KIAA0782" EXACT [UniProtKB:Q96P48] xref: EMBL:AB018325 xref: EMBL:AB209473 xref: EMBL:AF411983 xref: EMBL:AJ621557 xref: EMBL:AY049732 xref: EMBL:BC008315 xref: EMBL:BC021244 xref: EMBL:BC056401 xref: HGNC:HGNC:16925 xref: UniGene:Hs.503165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002052 ! CEND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004322 name: CENPB_human def: "Major centromere autoantigen B gene" [UniProtKB:P07199] xref: EMBL:AL109804 xref: EMBL:BC053847 xref: EMBL:X05299 xref: EMBL:X55039 xref: HGNC:HGNC:1852 xref: UniGene:Hs.516855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005431 ! CENPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004323 name: CENPC1_human def: "Centromere protein C 1 gene" [UniProtKB:Q03188] synonym: "CENPC" EXACT [UniProtKB:Q03188] synonym: "ICEN7" EXACT [UniProtKB:Q03188] xref: EMBL:AF151723 xref: EMBL:M95724 xref: HGNC:HGNC:1854 xref: UniGene:Hs.479867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005470 ! CENPC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004324 name: CENPE_human def: "Centromeric protein E gene" [UniProtKB:Q02224] xref: EMBL:AB209996 xref: EMBL:AC079919 xref: EMBL:CH471057 xref: EMBL:Z15005 xref: HGNC:HGNC:1856 xref: UniGene:Hs.75573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001715 ! CENPE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004325 name: CENPF_human def: "Centromere protein F gene" [UniProtKB:P49454] xref: EMBL:AL445305 xref: EMBL:AL445666 xref: EMBL:U19769 xref: EMBL:U25725 xref: EMBL:U30872 xref: HGNC:HGNC:1857 xref: UniGene:Hs.497741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001629 ! CENPF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004326 name: CENPH_human def: "Centromere protein H gene" [UniProtKB:Q9H3R5] synonym: "ICEN35" EXACT [UniProtKB:Q9H3R5] xref: EMBL:AB035124 xref: EMBL:BC012024 xref: EMBL:BC015355 xref: HGNC:HGNC:17268 xref: UniGene:Hs.631967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005682 ! CENPH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004327 name: CENPJ_human def: "Centromere protein J gene" [UniProtKB:Q9HC77] synonym: "CPAP" EXACT [UniProtKB:Q9HC77] synonym: "LAP" EXACT [UniProtKB:Q9HC77] synonym: "LIP1" EXACT [UniProtKB:Q9HC77] xref: EMBL:AF139625 xref: EMBL:AF141337 xref: EMBL:AJ303006 xref: EMBL:AL354798 xref: EMBL:BC024209 xref: EMBL:BC113110 xref: EMBL:BC113662 xref: EMBL:BC113664 xref: HGNC:HGNC:17272 xref: UniGene:Hs.513379 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005426 ! CENPJ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004328 name: ITGB3BP_human def: "Centromere protein R gene" [UniProtKB:Q13352] synonym: "CENPR" EXACT [UniProtKB:Q13352] synonym: "NRIF3" EXACT [UniProtKB:Q13352] xref: EMBL:AF175306 xref: EMBL:AL592218 xref: EMBL:BC009929 xref: EMBL:BC014385 xref: EMBL:BX004807 xref: EMBL:U37139 xref: HGNC:HGNC:6157 xref: UniGene:Hs.166539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006198 ! CENPR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004329 name: CEP55_human def: "Centrosomal protein of 55 kDa gene" [UniProtKB:Q53EZ4] synonym: "C10orf3" EXACT [UniProtKB:Q53EZ4] synonym: "URCC6" EXACT [UniProtKB:Q53EZ4] xref: EMBL:AB091343 xref: EMBL:AK001402 xref: EMBL:AK223495 xref: EMBL:AL356214 xref: EMBL:AY788918 xref: EMBL:BC008947 xref: EMBL:BX640718 xref: HGNC:HGNC:1161 xref: UniGene:Hs.14559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001837 ! CEP55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004330 name: CEP63_human def: "Centrosomal protein of 63 kDa gene" [UniProtKB:Q96MT8] xref: EMBL:AK023448 xref: EMBL:AK023738 xref: EMBL:AK056465 xref: EMBL:BC014050 xref: EMBL:BC068997 xref: EMBL:BK005503 xref: HGNC:HGNC:25815 xref: UniGene:Hs.443301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005590 ! CEP63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004331 name: CEP76_human def: "Centrosomal protein of 76 kDa gene" [UniProtKB:Q8TAP6] synonym: "C18orf9" EXACT [UniProtKB:Q8TAP6] xref: EMBL:AK022604 xref: EMBL:AL833727 xref: EMBL:BC026307 xref: HGNC:HGNC:25727 xref: UniGene:Hs.236940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005244 ! CEP76_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004332 name: CETN1_human def: "Centrin-1 gene" [UniProtKB:Q12798] synonym: "CEN1" EXACT [UniProtKB:Q12798] synonym: "CETN" EXACT [UniProtKB:Q12798] xref: EMBL:BC029515 xref: EMBL:U03270 xref: HGNC:HGNC:1866 xref: UniGene:Hs.122511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001731 ! CETN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004333 name: CETN2_human def: "Centrin-2 gene" [UniProtKB:P41208] synonym: "CALT" EXACT [UniProtKB:P41208] synonym: "CEN2" EXACT [UniProtKB:P41208] xref: EMBL:AY919675 xref: EMBL:BC005334 xref: EMBL:BC013873 xref: EMBL:BT007256 xref: EMBL:U82671 xref: EMBL:X72964 xref: HGNC:HGNC:1867 xref: UniGene:Hs.82794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001604 ! CETN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004334 name: CETN3_human def: "Centrin-3 gene" [UniProtKB:O15182] synonym: "CEN3" EXACT [UniProtKB:O15182] xref: EMBL:BC005383 xref: EMBL:BC093793 xref: EMBL:BC112040 xref: EMBL:BT006688 xref: EMBL:Y12473 xref: HGNC:HGNC:1868 xref: UniGene:Hs.591767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001368 ! CETN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004335 name: CFTR_human def: "Cystic fibrosis transmembrane conductance regulator gene" [UniProtKB:P13569] synonym: "ABCC7" EXACT [UniProtKB:P13569] xref: EMBL:AC000061 xref: EMBL:AC000111 xref: EMBL:CH236947 xref: EMBL:DQ354388 xref: EMBL:DQ354389 xref: EMBL:DQ354390 xref: EMBL:DQ354391 xref: EMBL:DQ356258 xref: EMBL:DQ356259 xref: EMBL:DQ356261 xref: EMBL:DQ356262 xref: EMBL:DQ356263 xref: EMBL:DQ356264 xref: EMBL:DQ388128 xref: EMBL:DQ388129 xref: EMBL:DQ388131 xref: EMBL:DQ388132 xref: EMBL:DQ388133 xref: EMBL:DQ388134 xref: EMBL:DQ388135 xref: EMBL:DQ388138 xref: EMBL:DQ388139 xref: EMBL:DQ388140 xref: EMBL:DQ388141 xref: EMBL:DQ388142 xref: EMBL:DQ388143 xref: EMBL:DQ388145 xref: EMBL:M28668 xref: EMBL:M55106 xref: EMBL:M55107 xref: EMBL:M55108 xref: EMBL:M55110 xref: EMBL:M55111 xref: EMBL:M55112 xref: EMBL:M55113 xref: EMBL:M55114 xref: EMBL:M55115 xref: EMBL:M55116 xref: EMBL:M55117 xref: EMBL:M55118 xref: EMBL:M55119 xref: EMBL:M55120 xref: EMBL:M55121 xref: EMBL:M55122 xref: EMBL:M55123 xref: EMBL:M55124 xref: EMBL:M55125 xref: EMBL:M55126 xref: EMBL:M55127 xref: EMBL:M55128 xref: EMBL:M55129 xref: EMBL:M55130 xref: EMBL:M55131 xref: EMBL:M65196 xref: EMBL:M65197 xref: HGNC:HGNC:1884 xref: UniGene:Hs.489786 xref: UniGene:Hs.621460 xref: UniGene:Hs.661104 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005605 ! CFTR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004336 name: C7orf20_human def: "UPF0363 protein C7orf20 gene" [UniProtKB:Q7L5D6] synonym: "CEE" EXACT [UniProtKB:Q7L5D6] synonym: "CGI-20" EXACT [UniProtKB:Q7L5D6] xref: EMBL:AF132954 xref: EMBL:AK024305 xref: EMBL:AK097899 xref: EMBL:AK125863 xref: EMBL:AL133014 xref: EMBL:BC003550 xref: EMBL:CH236965 xref: HGNC:HGNC:21690 xref: UniGene:Hs.107387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006174 ! CG020_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004337 name: C7orf25_human def: "UPF0415 protein C7orf25 gene" [UniProtKB:Q9BPX7] xref: EMBL:AK024820 xref: EMBL:BC000769 xref: EMBL:BC001845 xref: HGNC:HGNC:21703 xref: UniGene:Hs.214247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006330 ! CG025_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004338 name: C7orf36_human def: "Uncharacterized protein C7orf36 gene" [UniProtKB:Q9NRH1] synonym: "GK003" EXACT [UniProtKB:Q9NRH1] xref: EMBL:AC011290 xref: EMBL:AF226046 xref: EMBL:BC022043 xref: EMBL:CR457198 xref: HGNC:HGNC:24857 xref: UniGene:Hs.83313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006249 ! CG036_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004339 name: CGREF1_human def: "Cell growth regulator with EF hand domain protein 1 gene" [UniProtKB:Q99674] synonym: "CGR11" EXACT [UniProtKB:Q99674] xref: EMBL:AC013403 xref: EMBL:AK290128 xref: EMBL:BC034764 xref: EMBL:CH471053 xref: EMBL:U66468 xref: HGNC:HGNC:16962 xref: UniGene:Hs.159525 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002081 ! CGRE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004340 name: CGRRF1_human def: "Cell growth regulator with RING finger domain protein 1 gene" [UniProtKB:Q99675] synonym: "CGR19" EXACT [UniProtKB:Q99675] synonym: "RNF197" EXACT [UniProtKB:Q99675] xref: EMBL:BC015063 xref: EMBL:U66469 xref: HGNC:HGNC:15528 xref: UniGene:Hs.59106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002082 ! CGRF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004341 name: C8orf32_human def: "Uncharacterized protein C8orf32 gene" [UniProtKB:Q96HA8] xref: EMBL:AK001066 xref: EMBL:BC008781 xref: HGNC:HGNC:25490 xref: UniGene:Hs.18029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005179 ! CH032_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004342 name: HSPE1_human def: "10 kDa heat shock protein, mitochondrial gene" [UniProtKB:P61604] xref: EMBL:AF107893 xref: EMBL:AF107894 xref: EMBL:AJ250915 xref: EMBL:BC023518 xref: EMBL:U07550 xref: EMBL:X75821 xref: HGNC:HGNC:5269 xref: UniGene:Hs.1197 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006092 ! CH10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004343 name: HSPD1_human def: "60 kDa heat shock protein, mitochondrial precursor gene" [UniProtKB:P10809] synonym: "HSP60" EXACT [UniProtKB:P10809] xref: EMBL:AJ250915 xref: EMBL:BC002676 xref: EMBL:BC003030 xref: EMBL:BC067082 xref: EMBL:BC073746 xref: EMBL:DQ217936 xref: EMBL:M22382 xref: EMBL:M34664 xref: HGNC:HGNC:5261 xref: UniGene:Hs.595053 xref: UniGene:Hs.632539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005730 ! CH60_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004344 name: CHD3_human def: "Chromodomain-helicase-DNA-binding protein 3 gene" [UniProtKB:Q12873] xref: EMBL:AF006515 xref: EMBL:U08379 xref: EMBL:U91543 xref: HGNC:HGNC:1918 xref: UniGene:Hs.25601 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006082 ! CHD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004345 name: CHD8_human def: "Chromodomain-helicase-DNA-binding protein 8 gene" [UniProtKB:Q9HCK8] synonym: "HELSNF1" EXACT [UniProtKB:Q9HCK8] synonym: "KIAA1564" EXACT [UniProtKB:Q9HCK8] xref: EMBL:AB046784 xref: EMBL:AL834524 xref: EMBL:BC011695 xref: EMBL:BC025964 xref: EMBL:BC036920 xref: EMBL:CB043942 xref: EMBL:CR749315 xref: HGNC:HGNC:20153 xref: UniGene:Hs.530698 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005444 ! CHD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004346 name: CHFR_human def: "E3 ubiquitin-protein ligase CHFR gene" [UniProtKB:Q96EP1] synonym: "RNF196" EXACT [UniProtKB:Q96EP1] xref: EMBL:AC127070 xref: EMBL:AF170724 xref: EMBL:AK001658 xref: EMBL:AK027687 xref: EMBL:AL137561 xref: EMBL:BC012072 xref: HGNC:HGNC:20455 xref: UniGene:Hs.656770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002035 ! CHFR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004347 name: CHEK1_human def: "Serine/threonine-protein kinase Chk1 gene" [UniProtKB:O14757] synonym: "CHK1" EXACT [UniProtKB:O14757] xref: EMBL:AB032387 xref: EMBL:AF016582 xref: EMBL:AF032874 xref: EMBL:AF527555 xref: EMBL:BC004202 xref: EMBL:BC017575 xref: HGNC:HGNC:1925 xref: UniGene:Hs.24529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001359 ! CHK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004348 name: CHEK2_human def: "Serine/threonine-protein kinase Chk2 gene" [UniProtKB:O96017] synonym: "CHK2" EXACT [UniProtKB:O96017] synonym: "RAD53" EXACT [UniProtKB:O96017] xref: EMBL:AB040105 xref: EMBL:AF086904 xref: EMBL:AF096279 xref: EMBL:AF174135 xref: EMBL:AJ131197 xref: EMBL:AL117330 xref: EMBL:AL121825 xref: EMBL:AY551295 xref: EMBL:AY551296 xref: EMBL:AY551297 xref: EMBL:AY551298 xref: EMBL:AY551299 xref: EMBL:AY551300 xref: EMBL:AY551301 xref: EMBL:AY551302 xref: EMBL:AY551303 xref: EMBL:AY551304 xref: EMBL:AY551305 xref: EMBL:AY800241 xref: EMBL:BC004207 xref: EMBL:CR456418 xref: HGNC:HGNC:16627 xref: UniGene:Hs.291363 xref: UniGene:Hs.505297 xref: UniGene:Hs.632780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001459 ! CHK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004349 name: CHMP1A_human def: "Charged multivesicular body protein 1a gene" [UniProtKB:Q9HD42] synonym: "CHMP1" EXACT [UniProtKB:Q9HD42] synonym: "KIAA0047" EXACT [UniProtKB:Q9HD42] synonym: "PCOLN3" EXACT [UniProtKB:Q9HD42] synonym: "PRSM1" EXACT [UniProtKB:Q9HD42] xref: EMBL:AC010538 xref: EMBL:AF281063 xref: EMBL:BC007527 xref: EMBL:BC010000 xref: EMBL:BC132711 xref: EMBL:BC132713 xref: EMBL:BT006841 xref: EMBL:D38554 xref: EMBL:U58048 xref: HGNC:HGNC:8740 xref: UniGene:Hs.589427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002148 ! CHM1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004350 name: CHMP4B_human def: "Charged multivesicular body protein 4b gene" [UniProtKB:Q9H444] synonym: "C20orf178" EXACT [UniProtKB:Q9H444] synonym: "SHAX1" EXACT [UniProtKB:Q9H444] xref: EMBL:AB100261 xref: EMBL:AL050349 xref: EMBL:AY329085 xref: EMBL:BC033859 xref: HGNC:HGNC:16171 xref: UniGene:Hs.472471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005270 ! CHM4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004352 name: CHST1_human def: "Carbohydrate sulfotransferase 1 gene" [UniProtKB:O43916] xref: EMBL:AB003791 xref: EMBL:AF090137 xref: EMBL:AY339617 xref: EMBL:BC022567 xref: EMBL:BC028235 xref: EMBL:U65637 xref: HGNC:HGNC:1969 xref: UniGene:Hs.104576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005247 ! CHST1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004353 name: C9orf82_human def: "Uncharacterized protein C9orf82 gene" [UniProtKB:Q9H8G2] xref: EMBL:AK023719 xref: EMBL:AL356133 xref: EMBL:BC014658 xref: EMBL:BC071953 xref: HGNC:HGNC:25834 xref: UniGene:Hs.178357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006175 ! CI082_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004354 name: CITED2_human def: "Cbp/p300-interacting transactivator 2 gene" [UniProtKB:Q99967] synonym: "MRG1" EXACT [UniProtKB:Q99967] xref: EMBL:AF109161 xref: EMBL:AF129290 xref: EMBL:AL592429 xref: EMBL:BC004377 xref: EMBL:U65093 xref: HGNC:HGNC:1987 xref: UniGene:Hs.82071 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002091 ! CITE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004357 name: C10orf119_human def: "UPF0557 protein C10orf119 gene" [UniProtKB:Q9BTE3] xref: EMBL:AK023143 xref: EMBL:BC000935 xref: EMBL:BC004183 xref: EMBL:BC007219 xref: EMBL:CR457299 xref: HGNC:HGNC:25782 xref: UniGene:Hs.124246 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005262 ! CJ119_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004358 name: CDK5RAP1_human def: "CDK5 regulatory subunit-associated protein 1 gene" [UniProtKB:Q96SZ6] synonym: "C20orf34" EXACT [UniProtKB:Q96SZ6] synonym: "CGI-05" EXACT [UniProtKB:Q96SZ6] synonym: "HSPC167" EXACT [UniProtKB:Q96SZ6] xref: EMBL:AF152097 xref: EMBL:AF161516 xref: EMBL:AK023992 xref: EMBL:AK027449 xref: EMBL:AL355392 xref: EMBL:BC001215 xref: EMBL:BC050706 xref: HGNC:HGNC:15880 xref: UniGene:Hs.435952 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002062 ! CK5P1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004359 name: CDK5RAP2_human def: "CDK5 regulatory subunit-associated protein 2 gene" [UniProtKB:Q96SN8] synonym: "CEP215" EXACT [UniProtKB:Q96SN8] synonym: "KIAA1633" EXACT [UniProtKB:Q96SN8] xref: EMBL:AB046853 xref: EMBL:AF448860 xref: EMBL:AK001729 xref: EMBL:AK025867 xref: EMBL:AK027636 xref: EMBL:AL133161 xref: EMBL:AL138836 xref: EMBL:AL353736 xref: EMBL:AL391870 xref: EMBL:AL590642 xref: EMBL:BC004526 xref: EMBL:BX537421 xref: EMBL:BX537759 xref: HGNC:HGNC:18672 xref: UniGene:Hs.269560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006178 ! CK5P2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004360 name: CDK5RAP3_human def: "CDK5 regulatory subunit-associated protein 3 gene" [UniProtKB:Q96JB5] synonym: "IC53" EXACT [UniProtKB:Q96JB5] synonym: "MSTP016" EXACT [UniProtKB:Q96JB5] synonym: "OK/SW-cl.114" EXACT [UniProtKB:Q96JB5] synonym: "PP1553" EXACT [UniProtKB:Q96JB5] xref: EMBL:AB062433 xref: EMBL:AF110322 xref: EMBL:AF217982 xref: EMBL:AF343090 xref: EMBL:AK023722 xref: EMBL:AK223387 xref: EMBL:BC009957 xref: EMBL:BC072435 xref: HGNC:HGNC:18673 xref: UniGene:Hs.20157 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002044 ! CK5P3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004361 name: CKAP2_human def: "Cytoskeleton-associated protein 2 gene" [UniProtKB:Q8WWK9] synonym: "LB1" EXACT [UniProtKB:Q8WWK9] synonym: "TMAP" EXACT [UniProtKB:Q8WWK9] xref: EMBL:AF177227 xref: EMBL:AJ429398 xref: EMBL:AK001611 xref: EMBL:AK022982 xref: EMBL:AL136848 xref: EMBL:AL359513 xref: EMBL:AY062261 xref: EMBL:AY062262 xref: EMBL:BC010901 xref: EMBL:BC105806 xref: EMBL:BC130296 xref: EMBL:EF560732 xref: EMBL:Y15758 xref: HGNC:HGNC:1990 xref: UniGene:Hs.444028 xref: UniGene:Hs.521482 xref: UniGene:Hs.653959 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002006 ! CKAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004362 name: CKAP4_human def: "Cytoskeleton-associated protein 4 gene" [UniProtKB:Q07065] xref: EMBL:AK223563 xref: EMBL:BC082972 xref: EMBL:BC094824 xref: EMBL:X69910 xref: HGNC:HGNC:16991 xref: UniGene:Hs.74368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005829 ! CKAP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004363 name: CKAP5_human def: "Cytoskeleton-associated protein 5 gene" [UniProtKB:Q14008] synonym: "KIAA0097" EXACT [UniProtKB:Q14008] xref: EMBL:AC115088 xref: EMBL:BC120869 xref: EMBL:D43948 xref: EMBL:X92474 xref: HGNC:HGNC:28959 xref: UniGene:Hs.201253 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001772 ! CKAP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004364 name: CKS1B_human def: "Cyclin-dependent kinases regulatory subunit 1 gene" [UniProtKB:P61024] synonym: "CKS1" EXACT [UniProtKB:P61024] synonym: "PNAS-143" EXACT [UniProtKB:P61024] synonym: "PNAS-16" EXACT [UniProtKB:P61024] xref: EMBL:AF274941 xref: EMBL:AF274943 xref: EMBL:AF279897 xref: EMBL:AL451085 xref: EMBL:BC007751 xref: EMBL:BC015629 xref: EMBL:BC070319 xref: EMBL:BC070320 xref: EMBL:BT007196 xref: EMBL:CH471121 xref: EMBL:X54941 xref: HGNC:HGNC:19083 xref: UniGene:Hs.374378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001686 ! CKS1_HUMAN relationship: codes_for CCO:B0001867 ! Q5T179_HUMAN relationship: codes_for CCO:B0002118 ! Q9BZU3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004365 name: CKS2_human def: "Cyclin-dependent kinases regulatory subunit 2 gene" [UniProtKB:P33552] xref: EMBL:AF506708 xref: EMBL:BC006458 xref: EMBL:X54942 xref: HGNC:HGNC:2000 xref: UniGene:Hs.83758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001586 ! CKS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004366 name: CLASP1_human def: "CLIP-associating protein 1 gene" [UniProtKB:Q7Z460] synonym: "KIAA0622" EXACT [UniProtKB:Q7Z460] synonym: "MAST1" EXACT [UniProtKB:Q7Z460] xref: EMBL:AB014522 xref: EMBL:AC012447 xref: EMBL:AC013399 xref: EMBL:AC079449 xref: EMBL:AF347693 xref: EMBL:AJ288057 xref: EMBL:BC032563 xref: EMBL:BC112940 xref: EMBL:CR933722 xref: HGNC:HGNC:17088 xref: UniGene:Hs.469840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001933 ! CLAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004367 name: CLASP2_human def: "CLIP-associating protein 2 gene" [UniProtKB:O75122] synonym: "KIAA0627" EXACT [UniProtKB:O75122] xref: EMBL:AB014527 xref: EMBL:AJ288058 xref: EMBL:AJ288059 xref: EMBL:AK024770 xref: EMBL:AL137636 xref: EMBL:BC029035 xref: HGNC:HGNC:17078 xref: UniGene:Hs.696092 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001422 ! CLAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004368 name: CLTA_human def: "Clathrin light chain A gene" [UniProtKB:P09496] xref: EMBL:AL158830 xref: EMBL:BC009201 xref: EMBL:BC019287 xref: EMBL:BT007170 xref: EMBL:DQ270158 xref: EMBL:M20471 xref: EMBL:M20472 xref: HGNC:HGNC:2090 xref: UniGene:Hs.522114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005448 ! CLCA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004369 name: CLTCL1_human def: "Clathrin heavy chain 2 gene" [UniProtKB:P53675] synonym: "CLH22" EXACT [UniProtKB:P53675] synonym: "CLTCL" EXACT [UniProtKB:P53675] synonym: "CLTD" EXACT [UniProtKB:P53675] xref: EMBL:U41763 xref: EMBL:U60802 xref: EMBL:U60803 xref: EMBL:X95486 xref: EMBL:X95487 xref: HGNC:HGNC:2093 xref: UniGene:Hs.368266 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005460 ! CLH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004370 name: CLIP1_human def: "CAP-Gly domain-containing linker protein 1 gene" [UniProtKB:P30622] synonym: "CYLN1" EXACT [UniProtKB:P30622] synonym: "RSN" EXACT [UniProtKB:P30622] xref: EMBL:M97501 xref: EMBL:X64838 xref: HGNC:HGNC:10461 xref: UniGene:Hs.524809 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001580 ! CLIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004371 name: CLK1_human def: "Dual specificity protein kinase CLK1 gene" [UniProtKB:P49759] synonym: "CLK" EXACT [UniProtKB:P49759] xref: EMBL:AC005037 xref: EMBL:BC031549 xref: EMBL:CH471063 xref: EMBL:L29219 xref: EMBL:L29222 xref: HGNC:HGNC:2068 xref: UniGene:Hs.433732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001632 ! CLK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004372 name: CLSPN_human def: "Claspin gene" [UniProtKB:Q9HAW4] xref: EMBL:AF297866 xref: EMBL:AL354864 xref: EMBL:BC038991 xref: EMBL:BC062215 xref: HGNC:HGNC:19715 xref: UniGene:Hs.175613 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002142 ! CLSPN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004374 name: C14orf48_human def: "Uncharacterized protein C14orf48 gene" [UniProtKB:Q8NCU1] xref: EMBL:AK097741 xref: EMBL:BC021728 xref: HGNC:HGNC:19860 xref: UniGene:Hs.143845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005286 ! CN048_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004375 name: CTNNBIP1_human def: "Beta-catenin-interacting protein 1 gene" [UniProtKB:Q9NSA3] synonym: "ICAT" EXACT [UniProtKB:Q9NSA3] xref: EMBL:AB021262 xref: EMBL:BC014300 xref: HGNC:HGNC:16913 xref: UniGene:Hs.463759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006076 ! CNBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004376 name: NCAPD2_human def: "Condensin complex subunit 1 gene" [UniProtKB:Q15021] synonym: "CAPD2" EXACT [UniProtKB:Q15021] synonym: "CNAP1" EXACT [UniProtKB:Q15021] synonym: "KIAA0159" EXACT [UniProtKB:Q15021] xref: EMBL:BC028182 xref: EMBL:D63880 xref: HGNC:HGNC:24305 xref: UniGene:Hs.5719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001801 ! CND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004377 name: NCAPH_human def: "Condensin complex subunit 2 gene" [UniProtKB:Q15003] synonym: "BRRN" EXACT [UniProtKB:Q15003] synonym: "BRRN1" EXACT [UniProtKB:Q15003] synonym: "CAPH" EXACT [UniProtKB:Q15003] synonym: "KIAA0074" EXACT [UniProtKB:Q15003] xref: EMBL:BC024211 xref: EMBL:D38553 xref: HGNC:HGNC:1112 xref: UniGene:Hs.308045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001797 ! CND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004378 name: NCAPG_human def: "Condensin complex subunit 3 gene" [UniProtKB:Q9BPX3] synonym: "CAPG" EXACT [UniProtKB:Q9BPX3] synonym: "NYMEL3" EXACT [UniProtKB:Q9BPX3] xref: EMBL:AB013299 xref: EMBL:AF235023 xref: EMBL:AF331796 xref: EMBL:AK022512 xref: EMBL:AK023147 xref: EMBL:AK027511 xref: EMBL:BC000827 xref: EMBL:BC002337 xref: EMBL:BC101476 xref: HGNC:HGNC:24304 xref: UniGene:Hs.446201 xref: UniGene:Hs.567567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002092 ! CND3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004379 name: NCAPD3_human def: "Condensin-2 complex subunit D3 gene" [UniProtKB:P42695] synonym: "CAPD3" EXACT [UniProtKB:P42695] synonym: "KIAA0056" EXACT [UniProtKB:P42695] xref: EMBL:AF070553 xref: EMBL:AP001775 xref: EMBL:BC098398 xref: EMBL:CH471065 xref: EMBL:D29954 xref: HGNC:HGNC:28952 xref: UniGene:Hs.438550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001614 ! CNDD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004380 name: NCAPG2_human def: "Condensin-2 complex subunit G2 gene" [UniProtKB:Q86XI2] synonym: "LUZP5" EXACT [UniProtKB:Q86XI2] xref: EMBL:AK022744 xref: EMBL:AK023347 xref: EMBL:BC005878 xref: EMBL:BC020560 xref: EMBL:BC043404 xref: EMBL:BX537845 xref: HGNC:HGNC:21904 xref: UniGene:Hs.18616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001943 ! CNDG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004382 name: CNTROB_human def: "Centrobin gene" [UniProtKB:Q8N137] synonym: "LIP8" EXACT [UniProtKB:Q8N137] synonym: "PP1221" EXACT [UniProtKB:Q8N137] xref: EMBL:AC104581 xref: EMBL:AF141344 xref: EMBL:AF331638 xref: EMBL:AK074847 xref: EMBL:AL137669 xref: EMBL:AL833907 xref: EMBL:AY160226 xref: EMBL:AY160227 xref: EMBL:BC014055 xref: EMBL:BC021134 xref: HGNC:HGNC:29616 xref: UniGene:Hs.348012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001961 ! CNTRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004383 name: ACACA_human def: "Acetyl-CoA carboxylase 1 gene" [UniProtKB:Q13085] synonym: "ACAC" EXACT [UniProtKB:Q13085] synonym: "ACC1" EXACT [UniProtKB:Q13085] synonym: "ACCA" EXACT [UniProtKB:Q13085] xref: EMBL:AJ534888 xref: EMBL:AJ534889 xref: EMBL:AJ564444 xref: EMBL:AY237919 xref: EMBL:AY315619 xref: EMBL:AY315620 xref: EMBL:AY315621 xref: EMBL:AY315623 xref: EMBL:AY315625 xref: EMBL:AY315627 xref: EMBL:U19822 xref: HGNC:HGNC:84 xref: UniGene:Hs.160556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035952 ! ACACA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004384 name: EBF1_human def: "Transcription factor COE1 gene" [UniProtKB:Q9UH73] synonym: "COE1" EXACT [UniProtKB:Q9UH73] synonym: "EBF" EXACT [UniProtKB:Q9UH73] xref: EMBL:AF208502 xref: EMBL:BC038805 xref: EMBL:BC041178 xref: HGNC:HGNC:3126 xref: UniGene:Hs.657753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006030 ! COE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004385 name: CORO1A_human def: "Coronin-1A gene" [UniProtKB:P31146] synonym: "CORO1" EXACT [UniProtKB:P31146] xref: EMBL:AF495470 xref: EMBL:BC110374 xref: EMBL:BC126385 xref: EMBL:BC126387 xref: EMBL:D44497 xref: EMBL:U34690 xref: EMBL:X89109 xref: HGNC:HGNC:2252 xref: UniGene:Hs.415067 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001581 ! COR1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004386 name: COX17_human def: "Cytochrome c oxidase copper chaperone gene" [UniProtKB:Q14061] xref: EMBL:AF269243 xref: EMBL:AF269244 xref: EMBL:BC010933 xref: EMBL:BC105280 xref: EMBL:BC108317 xref: EMBL:L77701 xref: HGNC:HGNC:2264 xref: UniGene:Hs.534383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006089 ! COX17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004387 name: COX6C_human def: "Cytochrome c oxidase polypeptide VIc precursor gene" [UniProtKB:P09669] xref: EMBL:AF067636 xref: EMBL:AF067637 xref: EMBL:BC000187 xref: EMBL:BT007007 xref: EMBL:X13238 xref: HGNC:HGNC:2285 xref: UniGene:Hs.351875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006181 ! COX6C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004389 name: CEP250_human def: "Centrosome-associated protein CEP250 gene" [UniProtKB:Q9BV73] synonym: "CEP2" EXACT [UniProtKB:Q9BV73] synonym: "CNAP1" EXACT [UniProtKB:Q9BV73] xref: EMBL:AF022655 xref: EMBL:AF049105 xref: EMBL:AL121586 xref: EMBL:BC001433 xref: HGNC:HGNC:1859 xref: UniGene:Hs.443976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002099 ! CP250_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004390 name: CYP26B1_human def: "Cytochrome P450 26B1 gene" [UniProtKB:Q9NR63] synonym: "CYP26A2" EXACT [UniProtKB:Q9NR63] synonym: "P450RAI2" EXACT [UniProtKB:Q9NR63] xref: EMBL:AC007002 xref: EMBL:AF252297 xref: EMBL:BC069443 xref: EMBL:BC109205 xref: HGNC:HGNC:20581 xref: UniGene:Hs.91546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002157 ! CP26B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004391 name: CAPNS1_human def: "Calpain small subunit 1 gene" [UniProtKB:P04632] synonym: "CAPN4" EXACT [UniProtKB:P04632] synonym: "CAPNS" EXACT [UniProtKB:P04632] xref: EMBL:AC002984 xref: EMBL:AD001527 xref: EMBL:AY789642 xref: EMBL:BC000592 xref: EMBL:BC007779 xref: EMBL:BC011903 xref: EMBL:BC017308 xref: EMBL:BC018931 xref: EMBL:BC021933 xref: EMBL:BC023643 xref: EMBL:BC064998 xref: EMBL:BT009775 xref: EMBL:M31502 xref: EMBL:M31503 xref: EMBL:M31504 xref: EMBL:M31505 xref: EMBL:M31506 xref: EMBL:M31507 xref: EMBL:M31508 xref: EMBL:M31509 xref: EMBL:M31510 xref: EMBL:M31511 xref: EMBL:X04106 xref: HGNC:HGNC:1481 xref: UniGene:Hs.515371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006088 ! CPNS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004392 name: C18orf25_human def: "Uncharacterized protein C18orf25 gene" [UniProtKB:Q96B23] xref: EMBL:AC021763 xref: EMBL:AK289738 xref: EMBL:AK292981 xref: EMBL:AL713661 xref: EMBL:AL832027 xref: EMBL:BC016149 xref: EMBL:BC084579 xref: EMBL:BX640683 xref: EMBL:CH471088 xref: HGNC:HGNC:28172 xref: UniGene:Hs.116486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005186 ! CR025_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004393 name: CRADD_human def: "Death domain-containing protein CRADD gene" [UniProtKB:P78560] synonym: "RAIDD" EXACT [UniProtKB:P78560] xref: EMBL:BC017042 xref: EMBL:BC037905 xref: EMBL:U79115 xref: EMBL:U84388 xref: HGNC:HGNC:2340 xref: UniGene:Hs.38533 xref: UniGene:Hs.591016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006182 ! CRADD_HUMAN relationship: codes_for CCO:B0057382 ! Q8IY43_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004394 name: MCC_human def: "Colorectal mutant cancer protein gene" [UniProtKB:P23508] xref: EMBL:BC009279 xref: EMBL:BC018919 xref: EMBL:M62397 xref: HGNC:HGNC:6935 xref: UniGene:Hs.593171 xref: UniGene:Hs.649603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001549 ! CRCM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004395 name: CREB1_human def: "cAMP response element-binding protein gene" [UniProtKB:P16220] xref: EMBL:BC010636 xref: EMBL:M27691 xref: EMBL:M34356 xref: EMBL:S53724 xref: EMBL:S72459 xref: EMBL:X55545 xref: EMBL:X60003 xref: HGNC:HGNC:2345 xref: UniGene:Hs.584750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005681 ! CREB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004396 name: CREB3_human def: "Cyclic AMP-responsive element-binding protein 3 gene" [UniProtKB:O43889] synonym: "LZIP" EXACT [UniProtKB:O43889] xref: EMBL:AF009368 xref: EMBL:AF029674 xref: EMBL:AF211847 xref: EMBL:AF211848 xref: EMBL:BC009402 xref: EMBL:BC010158 xref: EMBL:U59629 xref: EMBL:U88528 xref: HGNC:HGNC:2347 xref: UniGene:Hs.522110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005498 ! CREB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004397 name: CRELD1_human def: "Cysteine-rich with EGF-like domain protein 1 precursor gene" [UniProtKB:Q96HD1] synonym: "CIRRIN" EXACT [UniProtKB:Q96HD1] synonym: "UNQ188/PRO214" EXACT [UniProtKB:Q96HD1] xref: EMBL:AC018809 xref: EMBL:AF452623 xref: EMBL:AK314113 xref: EMBL:AL050275 xref: EMBL:AY358363 xref: EMBL:BC008720 xref: EMBL:CR457380 xref: HGNC:HGNC:14630 xref: UniGene:Hs.9383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006132 ! CREL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004398 name: CRNKL1_human def: "Crooked neck-like protein 1 gene" [UniProtKB:Q9BZJ0] synonym: "CGI-201" EXACT [UniProtKB:Q9BZJ0] synonym: "CRN" EXACT [UniProtKB:Q9BZJ0] synonym: "MSTP021" EXACT [UniProtKB:Q9BZJ0] xref: EMBL:AF111802 xref: EMBL:AF255443 xref: EMBL:AF318302 xref: EMBL:AF318303 xref: EMBL:AF318304 xref: EMBL:AF318305 xref: EMBL:AK022908 xref: EMBL:AK023246 xref: EMBL:AK023728 xref: EMBL:AL035454 xref: HGNC:HGNC:15762 xref: UniGene:Hs.171342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005593 ! CRNL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004399 name: CROCC_human def: "Rootletin gene" [UniProtKB:Q5TZA2] synonym: "KIAA0445" EXACT [UniProtKB:Q5TZA2] xref: EMBL:AB007914 xref: EMBL:AF527734 xref: EMBL:AL049569 xref: EMBL:BK005505 xref: EMBL:BX284668 xref: EMBL:DQ139275 xref: HGNC:HGNC:21299 xref: UniGene:Hs.309403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001895 ! CROCC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004400 name: C19orf25_human def: "UPF0449 protein C19orf25 gene" [UniProtKB:Q9UFG5] xref: EMBL:AK093985 xref: EMBL:AL122089 xref: EMBL:BC018441 xref: HGNC:HGNC:26711 xref: UniGene:Hs.532840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006066 ! CS025_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004401 name: C19orf50_human def: "UPF0459 protein C19orf50 gene" [UniProtKB:Q9BQD3] xref: EMBL:AC005253 xref: EMBL:BC001080 xref: EMBL:BC006479 xref: HGNC:HGNC:28420 xref: UniGene:Hs.369785 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005184 ! CS050_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004402 name: CSNK2A1_human def: "Casein kinase II subunit alpha gene" [UniProtKB:P68400] synonym: "CK2A1" EXACT [UniProtKB:P68400] xref: EMBL:AL049761 xref: EMBL:BC011668 xref: EMBL:BC053532 xref: EMBL:BC071167 xref: EMBL:J02853 xref: EMBL:M55265 xref: EMBL:X70251 xref: HGNC:HGNC:2457 xref: UniGene:Hs.654675 xref: UniGene:Hs.701971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005428 ! CSK21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004403 name: CSNK2A2_human def: "Casein kinase II subunit alpha' gene" [UniProtKB:P19784] synonym: "CK2A2" EXACT [UniProtKB:P19784] xref: EMBL:BC008812 xref: EMBL:M55268 xref: HGNC:HGNC:2459 xref: UniGene:Hs.82201 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001537 ! CSK22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004404 name: CSNK2B_human def: "Casein kinase II subunit beta gene" [UniProtKB:P67870] synonym: "CK2N" EXACT [UniProtKB:P67870] synonym: "G5A" EXACT [UniProtKB:P67870] xref: EMBL:AF129756 xref: EMBL:AL662899 xref: EMBL:AL670886 xref: EMBL:AL805934 xref: EMBL:AY113186 xref: EMBL:BA000025 xref: EMBL:BC112017 xref: EMBL:BC112019 xref: EMBL:CR541699 xref: EMBL:DQ314868 xref: EMBL:M30448 xref: EMBL:X16312 xref: EMBL:X16937 xref: EMBL:X57152 xref: HGNC:HGNC:2460 xref: UniGene:Hs.73527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005897 ! CSK2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004405 name: CSK_human def: "Tyrosine-protein kinase CSK gene" [UniProtKB:P41240] xref: EMBL:BC104847 xref: EMBL:BC104875 xref: EMBL:BC106073 xref: EMBL:CR541960 xref: EMBL:DQ075211 xref: EMBL:X59932 xref: EMBL:X60114 xref: EMBL:X74765 xref: HGNC:HGNC:2444 xref: UniGene:Hs.77793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001606 ! CSK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004406 name: CSMD1_human def: "CUB and sushi domain-containing protein 1 precursor gene" [UniProtKB:Q96PZ7] synonym: "KIAA1890" EXACT [UniProtKB:Q96PZ7] synonym: "UNQ5952/PRO19863" EXACT [UniProtKB:Q96PZ7] xref: EMBL:AB067477 xref: EMBL:AF333704 xref: EMBL:AK126936 xref: EMBL:AY017307 xref: EMBL:AY358174 xref: EMBL:DQ384438 xref: EMBL:DQ384439 xref: EMBL:DQ384440 xref: EMBL:DQ384441 xref: EMBL:DQ384442 xref: HGNC:HGNC:14026 xref: UniGene:Hs.571466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006004 ! CSMD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004407 name: GPS1_human def: "COP9 signalosome complex subunit 1 gene" [UniProtKB:Q13098] synonym: "COPS1" EXACT [UniProtKB:Q13098] synonym: "CSN1" EXACT [UniProtKB:Q13098] xref: EMBL:AK093283 xref: EMBL:BC000155 xref: EMBL:BC064503 xref: EMBL:BT009834 xref: EMBL:U20285 xref: HGNC:HGNC:4549 xref: UniGene:Hs.268530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001740 ! CSN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004408 name: COPS5_human def: "COP9 signalosome complex subunit 5 gene" [UniProtKB:Q92905] synonym: "CSN5" EXACT [UniProtKB:Q92905] synonym: "JAB1" EXACT [UniProtKB:Q92905] xref: EMBL:AY078082 xref: EMBL:BC001187 xref: EMBL:BC001859 xref: EMBL:BC007272 xref: EMBL:BX648542 xref: EMBL:CR541678 xref: EMBL:U65928 xref: EMBL:U70734 xref: HGNC:HGNC:2240 xref: UniGene:Hs.491912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002025 ! CSN5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004409 name: COPS6_human def: "COP9 signalosome complex subunit 6 gene" [UniProtKB:Q7L5N1] synonym: "CSN6" EXACT [UniProtKB:Q7L5N1] synonym: "HVIP" EXACT [UniProtKB:Q7L5N1] xref: EMBL:BC002520 xref: EMBL:U70735 xref: HGNC:HGNC:21749 xref: UniGene:Hs.15591 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006133 ! CSN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004410 name: COPS7A_human def: "COP9 signalosome complex subunit 7a gene" [UniProtKB:Q9UBW8] synonym: "CSN7A" EXACT [UniProtKB:Q9UBW8] synonym: "DERP10" EXACT [UniProtKB:Q9UBW8] xref: EMBL:AB014764 xref: EMBL:AB033603 xref: EMBL:AF193844 xref: EMBL:AF210052 xref: EMBL:AK001318 xref: EMBL:AK022488 xref: EMBL:BC011789 xref: HGNC:HGNC:16758 xref: UniGene:Hs.530823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006264 ! CSN7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004411 name: C20orf12_human def: "Ankyrin repeat-containing protein C20orf12 gene" [UniProtKB:Q9NVP4] synonym: "C20orf84" EXACT [UniProtKB:Q9NVP4] xref: EMBL:AK001462 xref: EMBL:AK055544 xref: EMBL:AK131451 xref: EMBL:AL049646 xref: EMBL:AL121893 xref: EMBL:CR749327 xref: EMBL:DQ104738 xref: HGNC:HGNC:15858 xref: UniGene:Hs.472225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005952 ! CT012_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004413 name: C20orf195_human def: "Uncharacterized protein C20orf195 gene" [UniProtKB:Q9BVV2] xref: EMBL:AL121829 xref: EMBL:BC000912 xref: HGNC:HGNC:28764 xref: UniGene:Hs.197755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005208 ! CT195_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004414 name: CTCF_human def: "Transcriptional repressor CTCF gene" [UniProtKB:P49711] xref: EMBL:AF145468 xref: EMBL:AF145469 xref: EMBL:AF145470 xref: EMBL:AF145471 xref: EMBL:AF145472 xref: EMBL:AF145473 xref: EMBL:AF145474 xref: EMBL:AF145475 xref: EMBL:AF145476 xref: EMBL:AF145477 xref: EMBL:BC014267 xref: EMBL:U25435 xref: HGNC:HGNC:13723 xref: UniGene:Hs.368367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001630 ! CTCF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004415 name: CTDSP1_human def: "Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 gene" [UniProtKB:Q9GZU7] synonym: "NIF3" EXACT [UniProtKB:Q9GZU7] synonym: "NLIIF" EXACT [UniProtKB:Q9GZU7] synonym: "SCP1" EXACT [UniProtKB:Q9GZU7] xref: EMBL:AF229162 xref: EMBL:AF229163 xref: EMBL:BC012977 xref: HGNC:HGNC:21614 xref: UniGene:Hs.444468 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005302 ! CTDS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004416 name: CTNNA1_human def: "Catenin alpha-1 gene" [UniProtKB:P35221] xref: EMBL:AF102787 xref: EMBL:AF102788 xref: EMBL:AF102789 xref: EMBL:AF102790 xref: EMBL:AF102791 xref: EMBL:AF102792 xref: EMBL:AF102793 xref: EMBL:AF102794 xref: EMBL:AF102795 xref: EMBL:AF102796 xref: EMBL:AF102797 xref: EMBL:AF102798 xref: EMBL:AF102799 xref: EMBL:AF102800 xref: EMBL:AF102801 xref: EMBL:AF102802 xref: EMBL:AF102803 xref: EMBL:AY884207 xref: EMBL:BC000385 xref: EMBL:D13866 xref: EMBL:D14705 xref: EMBL:L22080 xref: EMBL:L23805 xref: EMBL:U03100 xref: HGNC:HGNC:2509 xref: UniGene:Hs.534797 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005824 ! CTNA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004417 name: CTNNB1_human def: "Catenin beta-1 gene" [UniProtKB:P35222] synonym: "CTNNB" EXACT [UniProtKB:P35222] synonym: "OK/SW-cl.35" EXACT [UniProtKB:P35222] synonym: "PRO2286" EXACT [UniProtKB:P35222] xref: EMBL:AB062292 xref: EMBL:AF130085 xref: EMBL:AY081165 xref: EMBL:AY463360 xref: EMBL:BC058926 xref: EMBL:X87838 xref: EMBL:Z19054 xref: HGNC:HGNC:2514 xref: UniGene:Hs.476018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005327 ! CTNB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004418 name: CTNND1_human def: "Catenin delta-1 gene" [UniProtKB:O60716] synonym: "KIAA0384" EXACT [UniProtKB:O60716] xref: EMBL:AB002382 xref: EMBL:AF062317 xref: EMBL:AF062318 xref: EMBL:AF062319 xref: EMBL:AF062320 xref: EMBL:AF062321 xref: EMBL:AF062322 xref: EMBL:AF062323 xref: EMBL:AF062324 xref: EMBL:AF062325 xref: EMBL:AF062326 xref: EMBL:AF062327 xref: EMBL:AF062328 xref: EMBL:AF062329 xref: EMBL:AF062330 xref: EMBL:AF062331 xref: EMBL:AF062332 xref: EMBL:AF062333 xref: EMBL:AF062334 xref: EMBL:AF062335 xref: EMBL:AF062336 xref: EMBL:AF062337 xref: EMBL:AF062338 xref: EMBL:AF062339 xref: EMBL:AF062340 xref: EMBL:AF062341 xref: EMBL:AF062342 xref: EMBL:AF062343 xref: EMBL:AF062344 xref: EMBL:AK292554 xref: EMBL:AY505564 xref: EMBL:BC075795 xref: HGNC:HGNC:2515 xref: UniGene:Hs.166011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005839 ! CTND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004419 name: CTNNAL1_human def: "Alpha-catulin gene" [UniProtKB:Q9UBT7] xref: EMBL:AF006070 xref: EMBL:AF030233 xref: EMBL:AF080071 xref: EMBL:AF134871 xref: EMBL:AF134872 xref: EMBL:AF134873 xref: EMBL:AF134874 xref: EMBL:AF134875 xref: EMBL:AF134876 xref: EMBL:AF134877 xref: EMBL:AF134878 xref: EMBL:AF134879 xref: EMBL:AF134880 xref: EMBL:AF134881 xref: EMBL:AF134882 xref: EMBL:AF134883 xref: EMBL:AF134884 xref: EMBL:AF134885 xref: EMBL:AF134886 xref: EMBL:AF134887 xref: EMBL:AF134888 xref: EMBL:AF135021 xref: EMBL:AK223230 xref: EMBL:AL050016 xref: EMBL:AL354797 xref: EMBL:AY523969 xref: EMBL:BC117208 xref: EMBL:BC117234 xref: EMBL:U97067 xref: HGNC:HGNC:2512 xref: UniGene:Hs.58488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005881 ! CTNL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004420 name: CIT_human def: "Citron Rho-interacting kinase gene" [UniProtKB:O14578] synonym: "KIAA0949" EXACT [UniProtKB:O14578] synonym: "STK21" EXACT [UniProtKB:O14578] xref: EMBL:AB023166 xref: EMBL:AC002563 xref: EMBL:AC004813 xref: EMBL:AC079317 xref: EMBL:AY209000 xref: EMBL:AY257469 xref: HGNC:HGNC:1985 xref: UniGene:Hs.119594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001356 ! CTRO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004421 name: CUL1_human def: "Cullin-1 gene" [UniProtKB:Q13616] xref: EMBL:AC005229 xref: EMBL:AF062536 xref: EMBL:BC125119 xref: EMBL:BC125120 xref: EMBL:BX537409 xref: EMBL:U58087 xref: HGNC:HGNC:2551 xref: UniGene:Hs.146806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001759 ! CUL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004422 name: CUL2_human def: "Cullin-2 gene" [UniProtKB:Q13617] xref: EMBL:AF126404 xref: EMBL:AL392046 xref: EMBL:BC009591 xref: EMBL:BC110901 xref: EMBL:U58088 xref: EMBL:U83410 xref: HGNC:HGNC:2552 xref: UniGene:Hs.82919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001760 ! CUL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004423 name: CUL3_human def: "Cullin-3 gene" [UniProtKB:Q13618] synonym: "KIAA0617" EXACT [UniProtKB:Q13618] xref: EMBL:AB014517 xref: EMBL:AF052147 xref: EMBL:AF062537 xref: EMBL:AF064087 xref: EMBL:AY337761 xref: EMBL:BC031844 xref: EMBL:BC039598 xref: EMBL:BC092409 xref: EMBL:U58089 xref: HGNC:HGNC:2553 xref: UniGene:Hs.372286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001761 ! CUL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004424 name: CUL4A_human def: "Cullin-4A gene" [UniProtKB:Q13619] xref: EMBL:AB012193 xref: EMBL:AB178950 xref: EMBL:AF077188 xref: EMBL:AL136221 xref: EMBL:AY365124 xref: EMBL:BC008308 xref: EMBL:U58090 xref: HGNC:HGNC:2554 xref: UniGene:Hs.339735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001762 ! CUL4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004425 name: CUL4B_human def: "Cullin-4B gene" [UniProtKB:Q13620] synonym: "KIAA0695" EXACT [UniProtKB:Q13620] xref: EMBL:AB014595 xref: EMBL:AC002476 xref: EMBL:AF212995 xref: EMBL:AY365125 xref: EMBL:BC036216 xref: EMBL:BX537787 xref: EMBL:U58091 xref: HGNC:HGNC:2555 xref: UniGene:Hs.102914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001763 ! CUL4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004426 name: CUL5_human def: "Cullin-5 gene" [UniProtKB:Q93034] synonym: "VACM1" EXACT [UniProtKB:Q93034] xref: EMBL:AF017061 xref: EMBL:AF327710 xref: EMBL:BC063306 xref: EMBL:X81882 xref: HGNC:HGNC:2556 xref: UniGene:Hs.440320 xref: UniGene:Hs.701122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002027 ! CUL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004427 name: CUL7_human def: "Cullin-7 gene" [UniProtKB:Q14999] synonym: "KIAA0076" EXACT [UniProtKB:Q14999] xref: EMBL:AL136304 xref: EMBL:AL355385 xref: EMBL:BC033647 xref: EMBL:D38548 xref: HGNC:HGNC:21024 xref: UniGene:Hs.520136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001795 ! CUL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004429 name: CUZD1_human def: "CUB and zona pellucida-like domain-containing protein 1 precursor gene" [UniProtKB:Q86UP6] synonym: "UNQ224/PRO257" EXACT [UniProtKB:Q86UP6] xref: EMBL:AC073585 xref: EMBL:AF305835 xref: EMBL:AL359747 xref: EMBL:AY260047 xref: EMBL:AY260048 xref: EMBL:AY260049 xref: EMBL:AY260050 xref: EMBL:AY358556 xref: EMBL:BX538283 xref: EMBL:BX538284 xref: HGNC:HGNC:17937 xref: UniGene:Hs.647182 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001940 ! CUZD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004430 name: CYLD_human def: "Probable ubiquitin carboxyl-terminal hydrolase CYLD gene" [UniProtKB:Q9NQC7] synonym: "CYLD1" EXACT [UniProtKB:Q9NQC7] synonym: "HSPC057" EXACT [UniProtKB:Q9NQC7] synonym: "KIAA0849" EXACT [UniProtKB:Q9NQC7] xref: EMBL:AB020656 xref: EMBL:AF161542 xref: EMBL:AJ250014 xref: EMBL:BC012342 xref: HGNC:HGNC:2584 xref: UniGene:Hs.578973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002153 ! CYLD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004431 name: CSTA_human def: "Cystatin-A gene" [UniProtKB:P01040] synonym: "STF1" EXACT [UniProtKB:P01040] synonym: "STFA" EXACT [UniProtKB:P01040] xref: EMBL:AB007774 xref: EMBL:BC010379 xref: EMBL:D88422 xref: EMBL:X05978 xref: HGNC:HGNC:2481 xref: UniGene:Hs.518198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006322 ! CYTA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004432 name: SPECC1L_human def: "Cytospin-A gene" [UniProtKB:Q69YQ0] synonym: "CYTSA" EXACT [UniProtKB:Q69YQ0] synonym: "KIAA0376" EXACT [UniProtKB:Q69YQ0] xref: EMBL:AB002374 xref: EMBL:AL832425 xref: EMBL:AY884293 xref: HGNC:HGNC:29022 xref: UniGene:Hs.474384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001906 ! CYTSA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004433 name: DAB2IP_human def: "Disabled homolog 2-interacting protein gene" [UniProtKB:Q5VWQ8] synonym: "AF9Q34" EXACT [UniProtKB:Q5VWQ8] synonym: "AIP1" EXACT [UniProtKB:Q5VWQ8] synonym: "KIAA1743" EXACT [UniProtKB:Q5VWQ8] xref: EMBL:AB051530 xref: EMBL:AF367051 xref: EMBL:AL365274 xref: EMBL:AY032952 xref: EMBL:BC146762 xref: EMBL:CH471090 xref: HGNC:HGNC:17294 xref: UniGene:Hs.522378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001899 ! DAB2P_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004434 name: DACH1_human def: "Dachshund homolog 1 gene" [UniProtKB:Q9UI36] synonym: "DACH" EXACT [UniProtKB:Q9UI36] xref: EMBL:AF069509 xref: EMBL:AF102546 xref: EMBL:AF356492 xref: EMBL:AJ005670 xref: EMBL:AL079278 xref: EMBL:AL138698 xref: EMBL:AL139186 xref: EMBL:AL163542 xref: EMBL:AL354995 xref: EMBL:BC021219 xref: HGNC:HGNC:2663 xref: UniGene:Hs.129452 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005195 ! DACH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004435 name: DAPK1_human def: "Death-associated protein kinase 1 gene" [UniProtKB:P53355] synonym: "DAPK" EXACT [UniProtKB:P53355] xref: EMBL:AL160279 xref: EMBL:AL161787 xref: EMBL:AL591852 xref: EMBL:BC113660 xref: EMBL:BT006935 xref: EMBL:CR749834 xref: EMBL:X76104 xref: HGNC:HGNC:2674 xref: UniGene:Hs.380277 xref: UniGene:Hs.693441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005482 ! DAPK1_HUMAN relationship: codes_for CCO:B0036527 ! Q5T8F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004436 name: DAPK3_human def: "Death-associated protein kinase 3 gene" [UniProtKB:O43293] synonym: "ZIPK" EXACT [UniProtKB:O43293] xref: EMBL:AB007144 xref: EMBL:AB022341 xref: EMBL:BC126430 xref: EMBL:BC126432 xref: HGNC:HGNC:2676 xref: UniGene:Hs.631844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006060 ! DAPK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004437 name: DAXX_human def: "Death domain-associated protein 6 gene" [UniProtKB:Q9UER7] synonym: "BING2" EXACT [UniProtKB:Q9UER7] synonym: "DAP6" EXACT [UniProtKB:Q9UER7] xref: EMBL:AB015051 xref: EMBL:AF006041 xref: EMBL:AF015956 xref: EMBL:AF039136 xref: EMBL:AF050179 xref: EMBL:AF097742 xref: EMBL:BC000220 xref: EMBL:Z97183 xref: EMBL:Z97184 xref: HGNC:HGNC:2681 xref: UniGene:Hs.336916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002196 ! DAXX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004438 name: DAZ1_human def: "Deleted in azoospermia protein 1 gene" [UniProtKB:Q9NQZ3] synonym: "DAZ" EXACT [UniProtKB:Q9NQZ3] xref: EMBL:AC006338 xref: EMBL:AF271087 xref: EMBL:AF271088 xref: HGNC:HGNC:2682 xref: UniGene:Hs.522868 xref: UniGene:Hs.70936 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005886 ! DAZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004439 name: DAZAP2_human def: "DAZ-associated protein 2 gene" [UniProtKB:Q15038] synonym: "KIAA0058" EXACT [UniProtKB:Q15038] xref: EMBL:AY430097 xref: EMBL:BC002334 xref: EMBL:BC007900 xref: EMBL:D31767 xref: HGNC:HGNC:2684 xref: UniGene:Hs.369761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005180 ! DAZP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004440 name: DBC1_human def: "Deleted in bladder cancer protein 1 precursor gene" [UniProtKB:O60477] synonym: "DBCCR1" EXACT [UniProtKB:O60477] synonym: "FAM5A" EXACT [UniProtKB:O60477] synonym: "IB3089A" EXACT [UniProtKB:O60477] xref: EMBL:AF027734 xref: EMBL:AL138894 xref: EMBL:AL353773 xref: EMBL:BC021560 xref: EMBL:BC065196 xref: EMBL:BC071702 xref: HGNC:HGNC:2687 xref: UniGene:Hs.532316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001409 ! DBC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004441 name: DBF4_human def: "Protein DBF4 homolog A gene" [UniProtKB:Q9UBU7] synonym: "ASK" EXACT [UniProtKB:Q9UBU7] synonym: "DBF4A" EXACT [UniProtKB:Q9UBU7] synonym: "ZDBF1" EXACT [UniProtKB:Q9UBU7] xref: EMBL:AB028069 xref: EMBL:AB028070 xref: EMBL:AC003083 xref: EMBL:AC005164 xref: EMBL:AF160249 xref: EMBL:AF160876 xref: EMBL:AK292569 xref: EMBL:BC036045 xref: EMBL:BC047693 xref: EMBL:CH236949 xref: EMBL:CH471091 xref: HGNC:HGNC:17364 xref: UniGene:Hs.485380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002194 ! DBF4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004442 name: DYNC1I1_human def: "Cytoplasmic dynein 1 intermediate chain 1 gene" [UniProtKB:O14576] synonym: "DNCI1" EXACT [UniProtKB:O14576] synonym: "DNCIC1" EXACT [UniProtKB:O14576] xref: EMBL:AC002452 xref: EMBL:AC002540 xref: EMBL:AC022261 xref: EMBL:AC091779 xref: EMBL:AF063228 xref: EMBL:AF123074 xref: EMBL:AK091339 xref: HGNC:HGNC:2963 xref: UniGene:Hs.440364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005648 ! DC1I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004443 name: DCC_human def: "Netrin receptor DCC precursor gene" [UniProtKB:P43146] xref: EMBL:M32286 xref: EMBL:M32288 xref: EMBL:M32290 xref: EMBL:M32292 xref: EMBL:M63696 xref: EMBL:M63698 xref: EMBL:M63700 xref: EMBL:M63702 xref: EMBL:M63718 xref: EMBL:X76132 xref: HGNC:HGNC:2701 xref: UniGene:Hs.579550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001619 ! DCC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004444 name: DCP1A_human def: "mRNA-decapping enzyme 1A gene" [UniProtKB:Q9NPI6] synonym: "SMIF" EXACT [UniProtKB:Q9NPI6] xref: EMBL:AJ275986 xref: EMBL:AK001969 xref: EMBL:AY146651 xref: EMBL:BC007439 xref: HGNC:HGNC:18714 xref: UniGene:Hs.476353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005432 ! DCP1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004445 name: DCP2_human def: "mRNA-decapping enzyme 2 gene" [UniProtKB:Q8IU60] synonym: "NUDT20" EXACT [UniProtKB:Q8IU60] xref: EMBL:AK090564 xref: EMBL:AY135173 xref: EMBL:AY146650 xref: EMBL:BC045596 xref: EMBL:BC064593 xref: HGNC:HGNC:24452 xref: UniGene:Hs.443875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005433 ! DCP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004446 name: DCLRE1A_human def: "DNA cross-link repair 1A protein gene" [UniProtKB:Q6PJP8] synonym: "KIAA0086" EXACT [UniProtKB:Q6PJP8] synonym: "SNM1" EXACT [UniProtKB:Q6PJP8] synonym: "SNM1A" EXACT [UniProtKB:Q6PJP8] xref: EMBL:AL592546 xref: EMBL:AY607842 xref: EMBL:BC013124 xref: EMBL:BC062582 xref: EMBL:D42045 xref: HGNC:HGNC:17660 xref: UniGene:Hs.1560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001916 ! DCR1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004447 name: DCTN1_human def: "Dynactin subunit 1 gene" [UniProtKB:Q14203] xref: EMBL:AF064203 xref: EMBL:AF064204 xref: EMBL:AF064205 xref: EMBL:AF086927 xref: EMBL:AF086928 xref: EMBL:AF086929 xref: EMBL:AF086930 xref: EMBL:AF086931 xref: EMBL:AF086932 xref: EMBL:AF086933 xref: EMBL:AF086934 xref: EMBL:AF086935 xref: EMBL:AF086936 xref: EMBL:AF086937 xref: EMBL:AF086938 xref: EMBL:AF086939 xref: EMBL:AF086940 xref: EMBL:AF086941 xref: EMBL:AF086942 xref: EMBL:AF086943 xref: EMBL:AF086944 xref: EMBL:AF086945 xref: EMBL:AF086946 xref: EMBL:AF086947 xref: EMBL:BC006163 xref: EMBL:BT006758 xref: EMBL:X98801 xref: HGNC:HGNC:2711 xref: UniGene:Hs.516111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001779 ! DCTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004448 name: DCTN2_human def: "Dynactin subunit 2 gene" [UniProtKB:Q13561] synonym: "DCTN50" EXACT [UniProtKB:Q13561] xref: EMBL:AY189155 xref: EMBL:BC000718 xref: EMBL:BC009468 xref: EMBL:BC014083 xref: EMBL:U50733 xref: HGNC:HGNC:2712 xref: UniGene:Hs.289123 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005177 ! DCTN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004449 name: DCTN3_human def: "Dynactin subunit 3 gene" [UniProtKB:O75935] synonym: "DCTN22" EXACT [UniProtKB:O75935] xref: EMBL:AF082513 xref: EMBL:AL160270 xref: EMBL:AL450283 xref: EMBL:BC000319 xref: EMBL:BC003004 xref: EMBL:BC107697 xref: EMBL:CH471071 xref: EMBL:CR541889 xref: HGNC:HGNC:2713 xref: UniGene:Hs.511768 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001440 ! DCTN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004450 name: DDB1_human def: "DNA damage-binding protein 1 gene" [UniProtKB:Q16531] synonym: "XAP1" EXACT [UniProtKB:Q16531] xref: EMBL:AJ002955 xref: EMBL:AP003108 xref: EMBL:AY960579 xref: EMBL:BC011686 xref: EMBL:BC050530 xref: EMBL:BC051764 xref: EMBL:CH471076 xref: EMBL:L40326 xref: EMBL:U18299 xref: EMBL:U32986 xref: HGNC:HGNC:2717 xref: UniGene:Hs.290758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005584 ! DDB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004451 name: DDB2_human def: "DNA damage-binding protein 2 gene" [UniProtKB:Q92466] xref: EMBL:AB107037 xref: EMBL:AB107038 xref: EMBL:AB107039 xref: EMBL:AB107040 xref: EMBL:AY220533 xref: EMBL:BC000093 xref: EMBL:BT007139 xref: EMBL:U18300 xref: HGNC:HGNC:2718 xref: UniGene:Hs.702063 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005658 ! DDB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004452 name: DDIT3_human def: "DNA damage-inducible transcript 3 gene" [UniProtKB:P35638] synonym: "CHOP" EXACT [UniProtKB:P35638] synonym: "GADD153" EXACT [UniProtKB:P35638] xref: EMBL:AY880949 xref: EMBL:BC003637 xref: EMBL:S40706 xref: EMBL:S62138 xref: HGNC:HGNC:2726 xref: UniGene:Hs.505777 xref: UniGene:Hs.690217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001594 ! DDIT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004453 name: DDR1_human def: "Epithelial discoidin domain-containing receptor 1 precursor gene" [UniProtKB:Q08345] synonym: "CAK" EXACT [UniProtKB:Q08345] synonym: "EDDR1" EXACT [UniProtKB:Q08345] synonym: "NEP" EXACT [UniProtKB:Q08345] synonym: "NTRK4" EXACT [UniProtKB:Q08345] synonym: "PTK3A" EXACT [UniProtKB:Q08345] synonym: "RTK6" EXACT [UniProtKB:Q08345] synonym: "TRKE" EXACT [UniProtKB:Q08345] xref: EMBL:AL662854 xref: EMBL:AL662870 xref: EMBL:AL773541 xref: EMBL:AL773589 xref: EMBL:BA000025 xref: EMBL:BC008716 xref: EMBL:BC013400 xref: EMBL:BX927194 xref: EMBL:CR759747 xref: EMBL:L11315 xref: EMBL:L20817 xref: EMBL:L57508 xref: EMBL:U48705 xref: EMBL:X74979 xref: EMBL:X98208 xref: EMBL:X99023 xref: EMBL:X99024 xref: EMBL:X99025 xref: EMBL:X99026 xref: EMBL:X99027 xref: EMBL:X99028 xref: EMBL:X99029 xref: EMBL:X99030 xref: EMBL:X99031 xref: EMBL:X99032 xref: EMBL:X99033 xref: EMBL:X99034 xref: EMBL:Z29093 xref: HGNC:HGNC:2730 xref: UniGene:Hs.631988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006158 ! DDR1_HUMAN relationship: codes_for CCO:B0019991 ! A2ABL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004454 name: DDX11_human def: "Probable ATP-dependent RNA helicase DDX11 gene" [UniProtKB:Q96FC9] synonym: "CHL1" EXACT [UniProtKB:Q96FC9] synonym: "CHLR1" EXACT [UniProtKB:Q96FC9] synonym: "KRG2" EXACT [UniProtKB:Q96FC9] xref: EMBL:BC050069 xref: EMBL:BC050522 xref: EMBL:U33833 xref: EMBL:U75967 xref: EMBL:U75968 xref: EMBL:X99583 xref: HGNC:HGNC:2736 xref: UniGene:Hs.443960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002037 ! DDX11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004455 name: DDX12_human def: "Probable ATP-dependent RNA helicase DDX12 gene" [UniProtKB:Q92771] synonym: "CHLR2" EXACT [UniProtKB:Q92771] xref: EMBL:AC092821 xref: EMBL:AC141557 xref: EMBL:U33834 xref: HGNC:HGNC:2737 xref: UniGene:Hs.504688 xref: UniGene:Hs.705570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002017 ! DDX12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004456 name: DDX21_human def: "Nucleolar RNA helicase 2 gene" [UniProtKB:Q9NR30] xref: EMBL:AF261903 xref: EMBL:AF261904 xref: EMBL:AF261905 xref: EMBL:AF261906 xref: EMBL:AF261907 xref: EMBL:AF261908 xref: EMBL:AF261909 xref: EMBL:AF261910 xref: EMBL:AF261911 xref: EMBL:AF261912 xref: EMBL:AF261913 xref: EMBL:AF261914 xref: EMBL:AF261915 xref: EMBL:AF261916 xref: EMBL:AF261917 xref: EMBL:AL359844 xref: EMBL:BC008071 xref: EMBL:CR749598 xref: EMBL:U41387 xref: HGNC:HGNC:2744 xref: UniGene:Hs.576875 xref: UniGene:Hs.705423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005805 ! DDX21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004457 name: DDX24_human def: "ATP-dependent RNA helicase DDX24 gene" [UniProtKB:Q9GZR7] xref: EMBL:AF214731 xref: EMBL:AK025162 xref: EMBL:AL136886 xref: EMBL:BC008847 xref: EMBL:BC009406 xref: HGNC:HGNC:13266 xref: UniGene:Hs.510328 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006183 ! DDX24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004458 name: DDX3X_human def: "ATP-dependent RNA helicase DDX3X gene" [UniProtKB:O00571] synonym: "DBX" EXACT [UniProtKB:O00571] synonym: "DDX3" EXACT [UniProtKB:O00571] xref: EMBL:AF000982 xref: EMBL:AF000983 xref: EMBL:AF061337 xref: EMBL:BC011819 xref: EMBL:U50553 xref: HGNC:HGNC:2745 xref: UniGene:Hs.380774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005773 ! DDX3X_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004459 name: DDX5_human def: "Probable ATP-dependent RNA helicase DDX5 gene" [UniProtKB:P17844] synonym: "G17P1" EXACT [UniProtKB:P17844] synonym: "HELR" EXACT [UniProtKB:P17844] synonym: "HLR1" EXACT [UniProtKB:P17844] xref: EMBL:AF015812 xref: EMBL:AJ010931 xref: EMBL:BC016027 xref: EMBL:BT006943 xref: EMBL:X15729 xref: EMBL:X52104 xref: HGNC:HGNC:2746 xref: UniGene:Hs.279806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005729 ! DDX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004460 name: DDX6_human def: "Probable ATP-dependent RNA helicase DDX6 gene" [UniProtKB:P26196] synonym: "HLR2" EXACT [UniProtKB:P26196] synonym: "RCK" EXACT [UniProtKB:P26196] xref: EMBL:BC065007 xref: EMBL:D17532 xref: EMBL:Z11685 xref: HGNC:HGNC:2747 xref: UniGene:Hs.654366 xref: UniGene:Hs.702484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006013 ! DDX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004461 name: DEC1_human def: "Deleted in esophageal cancer 1 gene" [UniProtKB:Q9P2X7] synonym: "CTS9" EXACT [UniProtKB:Q9P2X7] xref: EMBL:AB022761 xref: EMBL:AL714001 xref: HGNC:HGNC:23658 xref: UniGene:Hs.148841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002189 ! DEC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004462 name: DEFA1_human def: "Neutrophil defensin 1 precursor gene" [UniProtKB:P59665] synonym: "DEF1" EXACT [UniProtKB:P59665] synonym: "DEFA2" EXACT [UniProtKB:P59665] synonym: "MRS" EXACT [UniProtKB:P59665] xref: EMBL:BC069423 xref: EMBL:L12690 xref: EMBL:M21130 xref: EMBL:M26602 xref: EMBL:X52053 xref: HGNC:HGNC:2761 xref: UniGene:Hs.380781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006339 ! DEF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004464 name: DEK_human def: "Protein DEK gene" [UniProtKB:P35659] xref: EMBL:AL031774 xref: EMBL:BC035259 xref: EMBL:X64229 xref: HGNC:HGNC:2768 xref: UniGene:Hs.695957 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005342 ! DEK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004465 name: DFNA5_human def: "Non-syndromic hearing impairment protein 5 gene" [UniProtKB:O60443] synonym: "ICERE1" EXACT [UniProtKB:O60443] xref: EMBL:AC003093 xref: EMBL:AF007790 xref: EMBL:AF073308 xref: EMBL:AF075171 xref: EMBL:AF131765 xref: EMBL:BC125065 xref: HGNC:HGNC:2810 xref: UniGene:Hs.520708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006267 ! DFNA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004466 name: DHCR24_human def: "24-dehydrocholesterol reductase precursor gene" [UniProtKB:Q15392] synonym: "KIAA0018" EXACT [UniProtKB:Q15392] xref: EMBL:AF261758 xref: EMBL:AF398336 xref: EMBL:AF398337 xref: EMBL:AF398338 xref: EMBL:AF398339 xref: EMBL:AF398340 xref: EMBL:AF398341 xref: EMBL:AF398342 xref: EMBL:BC004375 xref: EMBL:BC011669 xref: EMBL:D13643 xref: HGNC:HGNC:2859 xref: UniGene:Hs.498727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001806 ! DHC24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004468 name: DHRS2_human def: "Dehydrogenase/reductase SDR family member 2 gene" [UniProtKB:Q13268] xref: EMBL:AF244132 xref: EMBL:AL135999 xref: EMBL:BC007339 xref: EMBL:U31875 xref: HGNC:HGNC:18349 xref: UniGene:Hs.272499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005756 ! DHRS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004470 name: DHX9_human def: "ATP-dependent RNA helicase A gene" [UniProtKB:Q08211] synonym: "DDX9" EXACT [UniProtKB:Q08211] synonym: "LKP" EXACT [UniProtKB:Q08211] synonym: "NDH2" EXACT [UniProtKB:Q08211] xref: EMBL:AL355999 xref: EMBL:AL662837 xref: EMBL:BC058896 xref: EMBL:L13848 xref: EMBL:Y10658 xref: HGNC:HGNC:2750 xref: UniGene:Hs.191518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005804 ! DHX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004471 name: CCDC85B_human def: "Coiled-coil domain-containing protein 85B gene" [UniProtKB:Q15834] synonym: "DIPA" EXACT [UniProtKB:Q15834] xref: EMBL:BC008796 xref: EMBL:U63825 xref: HGNC:HGNC:24926 xref: UniGene:Hs.66713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043862 ! CC85B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004472 name: DIRAS2_human def: "GTP-binding protein Di-Ras2 gene" [UniProtKB:Q96HU8] xref: EMBL:AB076889 xref: EMBL:AL353619 xref: EMBL:BC008065 xref: HGNC:HGNC:19323 xref: UniGene:Hs.165636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005851 ! DIRA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004473 name: DIRAS3_human def: "GTP-binding protein Di-Ras3 gene" [UniProtKB:O95661] synonym: "ARHI" EXACT [UniProtKB:O95661] synonym: "NOEY2" EXACT [UniProtKB:O95661] synonym: "RHOI" EXACT [UniProtKB:O95661] xref: EMBL:AF202543 xref: EMBL:AL157407 xref: EMBL:BC005362 xref: EMBL:CR541870 xref: EMBL:CR541892 xref: EMBL:U96750 xref: HGNC:HGNC:687 xref: UniGene:Hs.194695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001453 ! DIRA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004474 name: DISC1_human def: "Disrupted in schizophrenia 1 protein gene" [UniProtKB:Q9NRI5] synonym: "KIAA0457" EXACT [UniProtKB:Q9NRI5] xref: EMBL:AB007926 xref: EMBL:AF222980 xref: EMBL:AF222983 xref: EMBL:AF222987 xref: EMBL:AJ506177 xref: EMBL:AJ506178 xref: EMBL:AL136171 xref: EMBL:AL161743 xref: EMBL:AL359543 xref: EMBL:AL445200 xref: EMBL:AL450284 xref: EMBL:AL626763 xref: HGNC:HGNC:2888 xref: UniGene:Hs.13318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005591 ! DISC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004475 name: DNAJB11_human def: "DnaJ homolog subfamily B member 11 precursor gene" [UniProtKB:Q9UBS4] synonym: "EDJ" EXACT [UniProtKB:Q9UBS4] synonym: "ERJ3" EXACT [UniProtKB:Q9UBS4] synonym: "PSEC0121" EXACT [UniProtKB:Q9UBS4] synonym: "UNQ537/PRO1080" EXACT [UniProtKB:Q9UBS4] xref: EMBL:AB028859 xref: EMBL:AF228505 xref: EMBL:AF277317 xref: EMBL:AJ250137 xref: EMBL:AK075300 xref: EMBL:AK075430 xref: EMBL:AY359043 xref: EMBL:BC001144 xref: EMBL:BT007063 xref: EMBL:CH471052 xref: EMBL:CR457096 xref: HGNC:HGNC:14889 xref: UniGene:Hs.317192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006136 ! DJB11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004476 name: DKC1_human def: "H/ACA ribonucleoprotein complex subunit 4 gene" [UniProtKB:O60832] synonym: "NOLA4" EXACT [UniProtKB:O60832] xref: EMBL:AF067008 xref: EMBL:AF067009 xref: EMBL:AF067010 xref: EMBL:AF067011 xref: EMBL:AF067012 xref: EMBL:AF067013 xref: EMBL:AF067014 xref: EMBL:AF067015 xref: EMBL:AF067016 xref: EMBL:AF067017 xref: EMBL:AF067018 xref: EMBL:AF067019 xref: EMBL:AF067020 xref: EMBL:AF067021 xref: EMBL:AF067022 xref: EMBL:AF067023 xref: EMBL:AJ010395 xref: EMBL:AJ010396 xref: EMBL:AJ224481 xref: EMBL:BC009928 xref: EMBL:BC010015 xref: EMBL:U59151 xref: HGNC:HGNC:2890 xref: UniGene:Hs.4747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001415 ! DKC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004477 name: DLEC1_human def: "Deleted in lung and esophageal cancer protein 1 gene" [UniProtKB:Q9Y238] synonym: "DLC1" EXACT [UniProtKB:Q9Y238] xref: EMBL:AB020522 xref: EMBL:AB026898 xref: EMBL:AL137282 xref: EMBL:AL137706 xref: HGNC:HGNC:2899 xref: UniGene:Hs.699962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002247 ! DLEC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004478 name: DLG1_human def: "Disks large homolog 1 gene" [UniProtKB:Q12959] xref: EMBL:U13896 xref: EMBL:U13897 xref: HGNC:HGNC:2900 xref: UniGene:Hs.292549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001736 ! DLG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004479 name: DLG5_human def: "Disks large homolog 5 gene" [UniProtKB:Q8TDM6] synonym: "KIAA0583" EXACT [UniProtKB:Q8TDM6] synonym: "PDLG" EXACT [UniProtKB:Q8TDM6] xref: EMBL:AB011155 xref: EMBL:AB091676 xref: EMBL:AF352033 xref: EMBL:AF352034 xref: EMBL:AL391421 xref: EMBL:AL450306 xref: EMBL:BC073996 xref: EMBL:BC117695 xref: EMBL:U61843 xref: HGNC:HGNC:2904 xref: UniGene:Hs.652690 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001993 ! DLG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004481 name: DLGAP4_human def: "Disks large-associated protein 4 gene" [UniProtKB:Q9Y2H0] synonym: "DAP4" EXACT [UniProtKB:Q9Y2H0] synonym: "KIAA0964" EXACT [UniProtKB:Q9Y2H0] synonym: "SAPAP4" EXACT [UniProtKB:Q9Y2H0] xref: EMBL:AB023181 xref: EMBL:AL050318 xref: EMBL:AL390374 xref: EMBL:BC108706 xref: EMBL:BC153874 xref: EMBL:CH471077 xref: HGNC:HGNC:24476 xref: UniGene:Hs.249600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006307 ! DLGP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004482 name: DYNLRB1_human def: "Dynein light chain roadblock-type 1 gene" [UniProtKB:Q9NP97] synonym: "BITH" EXACT [UniProtKB:Q9NP97] synonym: "DNCL2A" EXACT [UniProtKB:Q9NP97] synonym: "DNLC2A" EXACT [UniProtKB:Q9NP97] synonym: "HSPC162" EXACT [UniProtKB:Q9NP97] xref: EMBL:AF132750 xref: EMBL:AF161511 xref: EMBL:AF165516 xref: EMBL:AF178431 xref: EMBL:AL109923 xref: EMBL:AL136173 xref: EMBL:AY026513 xref: EMBL:BC002481 xref: EMBL:BC007223 xref: HGNC:HGNC:15468 xref: UniGene:Hs.593920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005562 ! DLRB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004483 name: DMAP1_human def: "DNA methyltransferase 1-associated protein 1 gene" [UniProtKB:Q9NPF5] synonym: "KIAA1425" EXACT [UniProtKB:Q9NPF5] xref: EMBL:AB037846 xref: EMBL:AF265228 xref: EMBL:AK021605 xref: EMBL:AL035417 xref: EMBL:AL136657 xref: EMBL:AL137200 xref: EMBL:AM393614 xref: EMBL:BC002855 xref: EMBL:BC008053 xref: EMBL:BX537895 xref: HGNC:HGNC:18291 xref: UniGene:Hs.8008 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005365 ! DMAP1_HUMAN relationship: codes_for CCO:B0056620 ! Q5TG39_HUMAN relationship: codes_for CCO:B0056621 ! Q5TG40_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004484 name: DMBT1_human def: "Deleted in malignant brain tumors 1 protein precursor gene" [UniProtKB:Q9UGM3] synonym: "GP340" EXACT [UniProtKB:Q9UGM3] xref: EMBL:AB020851 xref: EMBL:AB209691 xref: EMBL:AF159456 xref: EMBL:AJ000342 xref: EMBL:AJ243211 xref: EMBL:AJ243212 xref: EMBL:AJ243224 xref: EMBL:AJ297935 xref: EMBL:AL603764 xref: EMBL:BC153299 xref: EMBL:BX640988 xref: HGNC:HGNC:2926 xref: UniGene:Hs.279611 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002197 ! DMBT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004485 name: DMC1_human def: "Meiotic recombination protein DMC1/LIM15 homolog gene" [UniProtKB:Q14565] synonym: "DMC1H" EXACT [UniProtKB:Q14565] synonym: "LIM15" EXACT [UniProtKB:Q14565] xref: EMBL:AL022320 xref: EMBL:AY520538 xref: EMBL:BC125163 xref: EMBL:BC125164 xref: EMBL:CR456486 xref: EMBL:D63882 xref: EMBL:D64108 xref: HGNC:HGNC:2927 xref: UniGene:Hs.339396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001784 ! DMC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004486 name: DMWD_human def: "Dystrophia myotonica WD repeat-containing protein gene" [UniProtKB:Q09019] synonym: "DM9" EXACT [UniProtKB:Q09019] xref: EMBL:AC011530 xref: EMBL:L08835 xref: EMBL:L19267 xref: HGNC:HGNC:2936 xref: UniGene:Hs.515474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001726 ! DMWD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004487 name: DNAJA1_human def: "DnaJ homolog subfamily A member 1 gene" [UniProtKB:P31689] synonym: "DNAJ2" EXACT [UniProtKB:P31689] synonym: "HDJ2" EXACT [UniProtKB:P31689] synonym: "HSJ2" EXACT [UniProtKB:P31689] synonym: "HSPF4" EXACT [UniProtKB:P31689] xref: EMBL:BC008182 xref: EMBL:BT007292 xref: EMBL:D13388 xref: EMBL:L08069 xref: HGNC:HGNC:5229 xref: UniGene:Hs.445203 xref: UniGene:Hs.703256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005835 ! DNJA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004488 name: DNAJA2_human def: "DnaJ homolog subfamily A member 2 gene" [UniProtKB:O60884] synonym: "CPR3" EXACT [UniProtKB:O60884] synonym: "HIRIP4" EXACT [UniProtKB:O60884] xref: EMBL:AF011793 xref: EMBL:AJ001309 xref: EMBL:BC013044 xref: EMBL:BC015809 xref: EMBL:Y13350 xref: HGNC:HGNC:14884 xref: UniGene:Hs.368078 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001418 ! DNJA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004489 name: DNAJA3_human def: "DnaJ homolog subfamily A member 3, mitochondrial precursor gene" [UniProtKB:Q96EY1] synonym: "HCA57" EXACT [UniProtKB:Q96EY1] synonym: "TID1" EXACT [UniProtKB:Q96EY1] xref: EMBL:AF061749 xref: EMBL:AF244136 xref: EMBL:AF411044 xref: EMBL:BC007225 xref: EMBL:BC011855 xref: EMBL:BC012343 xref: EMBL:BC014062 xref: EMBL:BC020248 xref: EMBL:BC030145 xref: EMBL:BC032100 xref: HGNC:HGNC:11808 xref: UniGene:Hs.459779 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005818 ! DNJA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004490 name: DNAJB6_human def: "DnaJ homolog subfamily B member 6 gene" [UniProtKB:O75190] synonym: "HSJ2" EXACT [UniProtKB:O75190] synonym: "MRJ" EXACT [UniProtKB:O75190] synonym: "MSJ1" EXACT [UniProtKB:O75190] xref: EMBL:AB014888 xref: EMBL:AB015798 xref: EMBL:AB015799 xref: EMBL:AB209859 xref: EMBL:AC079306 xref: EMBL:AF060703 xref: EMBL:AF075601 xref: EMBL:AF080569 xref: EMBL:AK223601 xref: EMBL:AL136707 xref: EMBL:BC000177 xref: EMBL:BC002446 xref: EMBL:CH236954 xref: EMBL:CR533498 xref: HGNC:HGNC:14888 xref: UniGene:Hs.490745 xref: UniGene:Hs.593923 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005696 ! DNJB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004491 name: DNAJB9_human def: "DnaJ homolog subfamily B member 9 gene" [UniProtKB:Q9UBS3] synonym: "MDG1" EXACT [UniProtKB:Q9UBS3] synonym: "UNQ743/PRO1471" EXACT [UniProtKB:Q9UBS3] xref: EMBL:AB026908 xref: EMBL:AF083247 xref: EMBL:AL080081 xref: EMBL:AY359045 xref: EMBL:BC028912 xref: HGNC:HGNC:6968 xref: UniGene:Hs.6790 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006137 ! DNJB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004492 name: LIG1_human def: "DNA ligase 1 gene" [UniProtKB:P18858] xref: EMBL:AF527418 xref: EMBL:BC108318 xref: EMBL:M36067 xref: HGNC:HGNC:6598 xref: UniGene:Hs.1770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001534 ! DNLI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004493 name: LIG3_human def: "DNA ligase 3 gene" [UniProtKB:P49916] xref: EMBL:AF491645 xref: EMBL:BC068005 xref: EMBL:CH471147 xref: EMBL:U40671 xref: EMBL:X84740 xref: HGNC:HGNC:6600 xref: UniGene:Hs.100299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001638 ! DNLI3_HUMAN relationship: codes_for CCO:B0024942 ! Q6NVK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004494 name: LIG4_human def: "DNA ligase 4 gene" [UniProtKB:P49917] xref: EMBL:AF479264 xref: EMBL:AL157762 xref: EMBL:BC037491 xref: EMBL:X83441 xref: HGNC:HGNC:6601 xref: UniGene:Hs.166091 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001639 ! DNLI4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004495 name: DNMT3B_human def: "DNA (cytosine-5)-methyltransferase 3B gene" [UniProtKB:Q9UBC3] xref: EMBL:AF129267 xref: EMBL:AF129268 xref: EMBL:AF129269 xref: EMBL:AF156487 xref: EMBL:AF156488 xref: EMBL:AF176228 xref: EMBL:AF331857 xref: EMBL:AL035071 xref: HGNC:HGNC:2979 xref: UniGene:Hs.643024 xref: UniGene:Hs.655708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005423 ! DNM3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004496 name: DOCK1_human def: "Dedicator of cytokinesis protein 1 gene" [UniProtKB:Q14185] xref: EMBL:AL157711 xref: EMBL:AL355316 xref: EMBL:AL359094 xref: EMBL:AL390920 xref: EMBL:AL607029 xref: EMBL:BX470155 xref: EMBL:BX470201 xref: EMBL:D50857 xref: HGNC:HGNC:2987 xref: UniGene:Hs.159195 xref: UniGene:Hs.645702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005802 ! DOCK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004497 name: APPL1_human def: "DCC-interacting protein 13-alpha gene" [UniProtKB:Q9UKG1] synonym: "APPL" EXACT [UniProtKB:Q9UKG1] synonym: "DIP13A" EXACT [UniProtKB:Q9UKG1] synonym: "KIAA1428" EXACT [UniProtKB:Q9UKG1] xref: EMBL:AB037849 xref: EMBL:AF169797 xref: EMBL:AF424738 xref: EMBL:BC028599 xref: HGNC:HGNC:24035 xref: UniGene:Hs.476415 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002219 ! DP13A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004498 name: APPL2_human def: "DCC-interacting protein 13-beta gene" [UniProtKB:Q8NEU8] synonym: "DIP13B" EXACT [UniProtKB:Q8NEU8] xref: EMBL:AK001521 xref: EMBL:AY113704 xref: EMBL:BC033731 xref: HGNC:HGNC:18242 xref: UniGene:Hs.506603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001980 ! DP13B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004499 name: DPH1_human def: "Diphthamide biosynthesis protein 1 gene" [UniProtKB:Q9BZG8] synonym: "DPH2L" EXACT [UniProtKB:Q9BZG8] synonym: "DPH2L1" EXACT [UniProtKB:Q9BZG8] synonym: "OVCA1" EXACT [UniProtKB:Q9BZG8] xref: EMBL:AF321876 xref: EMBL:BC003099 xref: EMBL:BC096088 xref: EMBL:BT019878 xref: EMBL:S81752 xref: EMBL:U34880 xref: HGNC:HGNC:3003 xref: UniGene:Hs.513856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002117 ! DPH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004500 name: POLA2_human def: "DNA polymerase subunit alpha B gene" [UniProtKB:Q14181] xref: EMBL:BC001347 xref: EMBL:BC002990 xref: EMBL:CR456737 xref: EMBL:L24559 xref: HGNC:HGNC:30073 xref: UniGene:Hs.201897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005509 ! DPOA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004501 name: POLD1_human def: "DNA polymerase delta catalytic subunit gene" [UniProtKB:P28340] synonym: "POLD" EXACT [UniProtKB:P28340] xref: EMBL:AY129569 xref: EMBL:BC008800 xref: EMBL:M80397 xref: EMBL:M81735 xref: HGNC:HGNC:9175 xref: UniGene:Hs.279413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001564 ! DPOD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004502 name: POLD2_human def: "DNA polymerase delta subunit 2 gene" [UniProtKB:P49005] xref: EMBL:AF239710 xref: EMBL:AY116646 xref: EMBL:BC000459 xref: EMBL:U21090 xref: HGNC:HGNC:9176 xref: UniGene:Hs.306791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005883 ! DPOD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004503 name: POLD3_human def: "DNA polymerase delta subunit 3 gene" [UniProtKB:Q15054] synonym: "KIAA0039" EXACT [UniProtKB:Q15054] xref: EMBL:D26018 xref: HGNC:HGNC:20932 xref: UniGene:Hs.82502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005884 ! DPOD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004504 name: POLD4_human def: "DNA polymerase delta subunit 4 gene" [UniProtKB:Q9HCU8] synonym: "POLDS" EXACT [UniProtKB:Q9HCU8] xref: EMBL:AF179890 xref: EMBL:AY928482 xref: HGNC:HGNC:14106 xref: UniGene:Hs.523829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005882 ! DPOD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004505 name: POLE_human def: "DNA polymerase epsilon catalytic subunit A gene" [UniProtKB:Q07864] synonym: "POLE1" EXACT [UniProtKB:Q07864] xref: EMBL:AY273166 xref: EMBL:L09561 xref: EMBL:S60080 xref: EMBL:U49356 xref: HGNC:HGNC:9177 xref: UniGene:Hs.524871 xref: UniGene:Hs.657680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001724 ! DPOE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004506 name: POLE2_human def: "DNA polymerase epsilon subunit 2 gene" [UniProtKB:P56282] synonym: "DPE2" EXACT [UniProtKB:P56282] xref: EMBL:AF025840 xref: EMBL:AF036899 xref: EMBL:AF387021 xref: EMBL:AF387022 xref: EMBL:AF387023 xref: EMBL:AF387024 xref: EMBL:AF387025 xref: EMBL:AF387026 xref: EMBL:AF387027 xref: EMBL:AF387028 xref: EMBL:AF387029 xref: EMBL:AF387030 xref: EMBL:AF387031 xref: EMBL:AF387032 xref: EMBL:AF387033 xref: EMBL:AF387034 xref: EMBL:AL139099 xref: EMBL:BC126218 xref: EMBL:BC126220 xref: EMBL:EF506887 xref: HGNC:HGNC:9178 xref: UniGene:Hs.162777 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005904 ! DPOE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004507 name: POLE3_human def: "DNA polymerase epsilon subunit 3 gene" [UniProtKB:Q9NRF9] synonym: "CHRAC17" EXACT [UniProtKB:Q9NRF9] xref: EMBL:AF226077 xref: EMBL:AF261689 xref: EMBL:AK074629 xref: EMBL:AK074762 xref: EMBL:AK074782 xref: EMBL:AL137066 xref: EMBL:AY720898 xref: EMBL:BC003166 xref: EMBL:BC004170 xref: EMBL:DQ072116 xref: HGNC:HGNC:13546 xref: UniGene:Hs.108112 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005885 ! DPOE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004508 name: POLE4_human def: "DNA polymerase epsilon subunit 4 gene" [UniProtKB:Q9NR33] xref: EMBL:AC007400 xref: EMBL:AF261688 xref: EMBL:BC031331 xref: HGNC:HGNC:18755 xref: UniGene:Hs.469060 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005905 ! DPOE4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004509 name: POLA1_human def: "DNA polymerase alpha catalytic subunit gene" [UniProtKB:P09884] synonym: "POLA" EXACT [UniProtKB:P09884] xref: EMBL:AC004655 xref: EMBL:AY275833 xref: EMBL:M64481 xref: EMBL:X06745 xref: HGNC:HGNC:9173 xref: UniGene:Hs.567319 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001503 ! DPOLA_HUMAN relationship: codes_for CCO:B0019813 ! A6NMQ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004510 name: CRMP1_human def: "Dihydropyrimidinase-related protein 1 gene" [UniProtKB:Q14194] synonym: "DPYSL1" EXACT [UniProtKB:Q14194] xref: EMBL:AF096140 xref: EMBL:AF096141 xref: EMBL:AF096142 xref: EMBL:AF096143 xref: EMBL:AF096144 xref: EMBL:AF096145 xref: EMBL:AF096146 xref: EMBL:AF096147 xref: EMBL:AF096148 xref: EMBL:AF096149 xref: EMBL:AF096150 xref: EMBL:AF096151 xref: EMBL:AF096152 xref: EMBL:BC000252 xref: EMBL:BC007613 xref: EMBL:BT006806 xref: EMBL:D78012 xref: EMBL:U17278 xref: HGNC:HGNC:2365 xref: UniGene:Hs.135270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006074 ! DPYL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004511 name: DRAP1_human def: "Dr1-associated corepressor gene" [UniProtKB:Q14919] xref: EMBL:BC010025 xref: EMBL:U41843 xref: EMBL:X96506 xref: HGNC:HGNC:3019 xref: UniGene:Hs.356742 xref: UniGene:Hs.381222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040686 ! NC2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004512 name: DBN1_human def: "Drebrin gene" [UniProtKB:Q16643] synonym: "D0S117E" EXACT [UniProtKB:Q16643] xref: EMBL:AC145098 xref: EMBL:AL110225 xref: EMBL:BC000283 xref: EMBL:BC007281 xref: EMBL:BC007567 xref: EMBL:D17530 xref: EMBL:U00802 xref: HGNC:HGNC:2695 xref: UniGene:Hs.130316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006302 ! DREB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004513 name: DSN1_human def: "Kinetochore-associated protein DSN1 homolog gene" [UniProtKB:Q9H410] synonym: "C20orf172" EXACT [UniProtKB:Q9H410] xref: EMBL:AK023408 xref: EMBL:AK093031 xref: EMBL:AL132768 xref: EMBL:BC058899 xref: HGNC:HGNC:16165 xref: UniGene:Hs.632268 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002134 ! DSN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004514 name: SHFM1_human def: "26S proteasome complex subunit DSS1 gene" [UniProtKB:P60896] synonym: "DSS1" EXACT [UniProtKB:P60896] synonym: "SHFDG1" EXACT [UniProtKB:P60896] xref: EMBL:AC073230 xref: EMBL:BC032782 xref: EMBL:U41515 xref: HGNC:HGNC:10845 xref: UniGene:Hs.489201 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005586 ! DSS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004515 name: DTNBP1_human def: "Dysbindin gene" [UniProtKB:Q96EV8] synonym: "My031" EXACT [UniProtKB:Q96EV8] xref: EMBL:AF061734 xref: EMBL:AF394226 xref: EMBL:AK054593 xref: EMBL:AL021978 xref: EMBL:AL022343 xref: EMBL:AL136637 xref: EMBL:AY265460 xref: EMBL:BC011912 xref: HGNC:HGNC:17328 xref: UniGene:Hs.571148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005258 ! DTBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004516 name: DTL_human def: "Denticleless protein homolog gene" [UniProtKB:Q9NZJ0] synonym: "CDT2" EXACT [UniProtKB:Q9NZJ0] synonym: "CDW1" EXACT [UniProtKB:Q9NZJ0] synonym: "DCAF2" EXACT [UniProtKB:Q9NZJ0] synonym: "L2DTL" EXACT [UniProtKB:Q9NZJ0] synonym: "RAMP" EXACT [UniProtKB:Q9NZJ0] xref: EMBL:AC092814 xref: EMBL:AF195765 xref: EMBL:AF345896 xref: EMBL:AK000742 xref: EMBL:AK001206 xref: EMBL:AK001261 xref: EMBL:AK027651 xref: EMBL:AL592297 xref: EMBL:AL606468 xref: EMBL:BC033297 xref: EMBL:BC033540 xref: EMBL:DQ641253 xref: HGNC:HGNC:30288 xref: UniGene:Hs.656473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005656 ! DTL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004517 name: DTNA_human def: "Dystrobrevin alpha gene" [UniProtKB:Q9Y4J8] synonym: "DRP3" EXACT [UniProtKB:Q9Y4J8] xref: EMBL:AJ009668 xref: EMBL:U26742 xref: EMBL:U26743 xref: EMBL:U26744 xref: EMBL:U46744 xref: EMBL:U46745 xref: EMBL:U46746 xref: EMBL:U84529 xref: EMBL:U84530 xref: EMBL:U84531 xref: EMBL:U84532 xref: EMBL:U84533 xref: EMBL:U84534 xref: EMBL:U84535 xref: EMBL:U84536 xref: EMBL:U84537 xref: EMBL:U84538 xref: EMBL:U84539 xref: EMBL:U84540 xref: EMBL:U84541 xref: EMBL:U84542 xref: EMBL:U84543 xref: EMBL:U84544 xref: EMBL:U84545 xref: EMBL:U84546 xref: EMBL:U84547 xref: EMBL:U84548 xref: EMBL:U84549 xref: EMBL:U84550 xref: EMBL:U84551 xref: HGNC:HGNC:3057 xref: UniGene:Hs.643454 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005954 ! DTNA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004518 name: DTYMK_human def: "Thymidylate kinase gene" [UniProtKB:P23919] synonym: "CDC8" EXACT [UniProtKB:P23919] synonym: "TMPK" EXACT [UniProtKB:P23919] synonym: "TYMK" EXACT [UniProtKB:P23919] xref: EMBL:BC001827 xref: EMBL:CR541986 xref: EMBL:L16991 xref: EMBL:X54729 xref: HGNC:HGNC:3061 xref: UniGene:Hs.471873 xref: UniGene:Hs.647895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001550 ! KTHY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004519 name: DUSP12_human def: "Dual specificity protein phosphatase 12 gene" [UniProtKB:Q9UNI6] xref: EMBL:AF119226 xref: EMBL:AL359541 xref: EMBL:BC006286 xref: EMBL:BT006633 xref: HGNC:HGNC:3067 xref: UniGene:Hs.416216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006186 ! DUS12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004520 name: DUSP13_human def: "Dual specificity protein phosphatase 13 gene" [UniProtKB:Q9UII6] synonym: "TMDP" EXACT [UniProtKB:Q9UII6] xref: EMBL:AB027004 xref: EMBL:AB103375 xref: EMBL:AL392111 xref: EMBL:BC009778 xref: HGNC:HGNC:19681 xref: UniGene:Hs.178170 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002207 ! DUS13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004521 name: DUSP1_human def: "Dual specificity protein phosphatase 1 gene" [UniProtKB:P28562] synonym: "CL100" EXACT [UniProtKB:P28562] synonym: "MKP1" EXACT [UniProtKB:P28562] synonym: "PTPN10" EXACT [UniProtKB:P28562] synonym: "VH1" EXACT [UniProtKB:P28562] xref: EMBL:BC022463 xref: EMBL:DQ301957 xref: EMBL:X68277 xref: HGNC:HGNC:3064 xref: UniGene:Hs.171695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001566 ! DUS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004522 name: DUSP4_human def: "Dual specificity protein phosphatase 4 gene" [UniProtKB:Q13115] synonym: "MKP2" EXACT [UniProtKB:Q13115] synonym: "VH2" EXACT [UniProtKB:Q13115] xref: EMBL:BC002671 xref: EMBL:BC014565 xref: EMBL:U21108 xref: EMBL:U48807 xref: HGNC:HGNC:3070 xref: UniGene:Hs.417962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001744 ! DUS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004523 name: DUSP6_human def: "Dual specificity protein phosphatase 6 gene" [UniProtKB:Q16828] synonym: "MKP3" EXACT [UniProtKB:Q16828] synonym: "PYST1" EXACT [UniProtKB:Q16828] xref: EMBL:AB013382 xref: EMBL:AB013601 xref: EMBL:AB013602 xref: EMBL:BC003143 xref: EMBL:BC003562 xref: EMBL:BC005047 xref: EMBL:BC037236 xref: EMBL:BT006895 xref: EMBL:X93920 xref: HGNC:HGNC:3072 xref: UniGene:Hs.298654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001824 ! DUS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004524 name: DVL2_human def: "Segment polarity protein dishevelled homolog DVL-2 gene" [UniProtKB:O14641] xref: EMBL:AF006012 xref: EMBL:BC014844 xref: HGNC:HGNC:3086 xref: UniGene:Hs.118640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005211 ! DVL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004525 name: DNAH9_human def: "Dynein heavy chain 9, axonemal gene" [UniProtKB:Q9NYC9] synonym: "DNAH17L" EXACT [UniProtKB:Q9NYC9] synonym: "DNAL1" EXACT [UniProtKB:Q9NYC9] synonym: "KIAA0357" EXACT [UniProtKB:Q9NYC9] xref: EMBL:AB002355 xref: EMBL:AC005209 xref: EMBL:AC005410 xref: EMBL:AC005701 xref: EMBL:AF257737 xref: EMBL:AJ132088 xref: EMBL:AJ404468 xref: HGNC:HGNC:2953 xref: UniGene:Hs.567259 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006028 ! DYH9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004526 name: DYNC1H1_human def: "Cytoplasmic dynein 1 heavy chain 1 gene" [UniProtKB:Q14204] synonym: "DHC1" EXACT [UniProtKB:Q14204] synonym: "DNCH1" EXACT [UniProtKB:Q14204] synonym: "DNCL" EXACT [UniProtKB:Q14204] synonym: "DNECL" EXACT [UniProtKB:Q14204] synonym: "DYHC" EXACT [UniProtKB:Q14204] synonym: "KIAA0325" EXACT [UniProtKB:Q14204] xref: EMBL:AB002323 xref: EMBL:AY682080 xref: EMBL:BC021297 xref: EMBL:L23958 xref: EMBL:U53530 xref: HGNC:HGNC:2961 xref: UniGene:Hs.649497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001780 ! DYHC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004527 name: DYNLL1_human def: "Dynein light chain 1, cytoplasmic gene" [UniProtKB:P63167] synonym: "DLC1" EXACT [UniProtKB:P63167] synonym: "DNCL1" EXACT [UniProtKB:P63167] synonym: "DNCLC1" EXACT [UniProtKB:P63167] synonym: "HDLC1" EXACT [UniProtKB:P63167] xref: EMBL:CR407672 xref: EMBL:U32944 xref: HGNC:HGNC:15476 xref: UniGene:Hs.5120 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006226 ! DYL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004528 name: DNM2_human def: "Dynamin-2 gene" [UniProtKB:P50570] synonym: "DYN2" EXACT [UniProtKB:P50570] xref: EMBL:AC007229 xref: EMBL:AC011475 xref: EMBL:AC011552 xref: EMBL:AC011554 xref: EMBL:AC112707 xref: EMBL:BC039596 xref: EMBL:BC054501 xref: EMBL:L36983 xref: HGNC:HGNC:2974 xref: UniGene:Hs.211463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001643 ! DYN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004529 name: DYRK2_human def: "Dual specificity tyrosine-phosphorylation-regulated kinase 2 gene" [UniProtKB:Q92630] xref: EMBL:BC005809 xref: EMBL:BC006375 xref: EMBL:Y09216 xref: EMBL:Y13493 xref: HGNC:HGNC:3093 xref: UniGene:Hs.173135 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005265 ! DYRK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004530 name: EIF2AK1_human def: "Eukaryotic translation initiation factor 2-alpha kinase 1 gene" [UniProtKB:Q9BQI3] synonym: "HRI" EXACT [UniProtKB:Q9BQI3] synonym: "KIAA1369" EXACT [UniProtKB:Q9BQI3] synonym: "PRO1362" EXACT [UniProtKB:Q9BQI3] xref: EMBL:AB037790 xref: EMBL:AF116634 xref: EMBL:AF147094 xref: EMBL:AF181071 xref: EMBL:AF183414 xref: EMBL:AF255050 xref: EMBL:AK075192 xref: EMBL:AL136563 xref: EMBL:AL834494 xref: EMBL:BC006524 xref: HGNC:HGNC:24921 xref: UniGene:Hs.520205 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005674 ! E2AK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004531 name: EIF2AK2_human def: "Interferon-induced, double-stranded RNA-activated protein kinase gene" [UniProtKB:P19525] synonym: "PKR" EXACT [UniProtKB:P19525] synonym: "PRKR" EXACT [UniProtKB:P19525] xref: EMBL:AC007899 xref: EMBL:AF167460 xref: EMBL:AF167462 xref: EMBL:AF167463 xref: EMBL:AF167464 xref: EMBL:AF167465 xref: EMBL:AF167466 xref: EMBL:AF167468 xref: EMBL:AF167470 xref: EMBL:AF167472 xref: EMBL:AY228338 xref: EMBL:BC093676 xref: EMBL:BC101475 xref: EMBL:M35663 xref: EMBL:M85294 xref: EMBL:U50634 xref: EMBL:U50635 xref: EMBL:U50636 xref: EMBL:U50637 xref: EMBL:U50638 xref: EMBL:U50639 xref: EMBL:U50640 xref: EMBL:U50641 xref: EMBL:U50642 xref: EMBL:U50643 xref: EMBL:U50644 xref: EMBL:U50645 xref: EMBL:U50646 xref: EMBL:U50647 xref: EMBL:U50648 xref: HGNC:HGNC:9437 xref: UniGene:Hs.131431 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001535 ! E2AK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004532 name: EIF2AK3_human def: "Eukaryotic translation initiation factor 2-alpha kinase 3 precursor gene" [UniProtKB:Q9NZJ5] synonym: "PEK" EXACT [UniProtKB:Q9NZJ5] synonym: "PERK" EXACT [UniProtKB:Q9NZJ5] xref: EMBL:AF110146 xref: EMBL:AF193339 xref: EMBL:AF284604 xref: EMBL:AF284605 xref: EMBL:AF284606 xref: EMBL:AF284607 xref: EMBL:AF284608 xref: EMBL:AF284609 xref: EMBL:AF284610 xref: EMBL:AF284611 xref: EMBL:AF284612 xref: EMBL:AF284613 xref: EMBL:AF284614 xref: EMBL:AF284615 xref: EMBL:BC126356 xref: HGNC:HGNC:3255 xref: UniGene:Hs.591589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006015 ! E2AK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004533 name: E2F1_human def: "Transcription factor E2F1 gene" [UniProtKB:Q01094] synonym: "RBBP3" EXACT [UniProtKB:Q01094] xref: EMBL:AF516106 xref: EMBL:AL121906 xref: EMBL:BC050369 xref: EMBL:BC058902 xref: EMBL:M96577 xref: EMBL:S49592 xref: EMBL:S74230 xref: EMBL:U47675 xref: EMBL:U47676 xref: EMBL:U47677 xref: HGNC:HGNC:3113 xref: UniGene:Hs.654393 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001713 ! E2F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004534 name: E2F2_human def: "Transcription factor E2F2 gene" [UniProtKB:Q14209] xref: EMBL:AF518877 xref: EMBL:AL021154 xref: EMBL:BC053676 xref: EMBL:L22846 xref: HGNC:HGNC:3114 xref: UniGene:Hs.194333 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001781 ! E2F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004535 name: E2F3_human def: "Transcription factor E2F3 gene" [UniProtKB:O00716] synonym: "KIAA0075" EXACT [UniProtKB:O00716] xref: EMBL:AF547386 xref: EMBL:AL132775 xref: EMBL:AL136303 xref: EMBL:BC099908 xref: EMBL:D38550 xref: EMBL:Y10479 xref: HGNC:HGNC:3115 xref: UniGene:Hs.269408 xref: UniGene:Hs.703174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001352 ! E2F3_HUMAN relationship: codes_for CCO:B0001833 ! Q499G5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004536 name: E2F4_human def: "Transcription factor E2F4 gene" [UniProtKB:Q16254] xref: EMBL:AC040160 xref: EMBL:AF250378 xref: EMBL:AF527540 xref: EMBL:BC033180 xref: EMBL:CH471092 xref: EMBL:S75174 xref: EMBL:U15641 xref: EMBL:X86096 xref: HGNC:HGNC:3118 xref: UniGene:Hs.108371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001817 ! E2F4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004537 name: E2F5_human def: "Transcription factor E2F5 gene" [UniProtKB:Q15329] xref: EMBL:AY162833 xref: EMBL:U15642 xref: EMBL:U31556 xref: EMBL:X86097 xref: EMBL:Z78409 xref: HGNC:HGNC:3119 xref: UniGene:Hs.445758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001804 ! E2F5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004538 name: E2F6_human def: "Transcription factor E2F6 gene" [UniProtKB:O75461] xref: EMBL:AC099344 xref: EMBL:AF041381 xref: EMBL:AF059292 xref: EMBL:AJ493061 xref: EMBL:AY083996 xref: EMBL:AY083997 xref: EMBL:AY551346 xref: EMBL:AY551347 xref: EMBL:BC008348 xref: EMBL:BC107740 xref: HGNC:HGNC:3120 xref: UniGene:Hs.603093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001429 ! E2F6_HUMAN relationship: codes_for CCO:B0001917 ! Q6Q9Z6_HUMAN relationship: codes_for CCO:B0025086 ! Q6Q9Z7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004539 name: E2F7_human def: "Transcription factor E2F7 gene" [UniProtKB:Q96AV8] xref: EMBL:AC025161 xref: EMBL:AC079030 xref: EMBL:AK097677 xref: EMBL:BC016658 xref: EMBL:BC017481 xref: HGNC:HGNC:23820 xref: UniGene:Hs.416375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002031 ! E2F7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004540 name: E2F8_human def: "Transcription factor E2F8 gene" [UniProtKB:A0AVK6] xref: EMBL:AB231781 xref: EMBL:AK026964 xref: EMBL:BC028244 xref: EMBL:BC090877 xref: EMBL:BC108700 xref: EMBL:BC126400 xref: EMBL:BC126402 xref: HGNC:HGNC:24727 xref: UniGene:Hs.523526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001317 ! E2F8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004541 name: EAF1_human def: "ELL-associated factor 1 gene" [UniProtKB:Q96JC9] xref: EMBL:AF272973 xref: EMBL:BC041329 xref: HGNC:HGNC:20907 xref: UniGene:Hs.474479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005363 ! EAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004542 name: EDC3_human def: "Enhancer of mRNA-decapping protein 3 gene" [UniProtKB:Q96F86] synonym: "LSM16" EXACT [UniProtKB:Q96F86] synonym: "PP844" EXACT [UniProtKB:Q96F86] synonym: "YJDC" EXACT [UniProtKB:Q96F86] synonym: "YJEFN2" EXACT [UniProtKB:Q96F86] xref: EMBL:AF193058 xref: EMBL:AK024781 xref: EMBL:BC011534 xref: EMBL:BC021271 xref: HGNC:HGNC:26114 xref: UniGene:Hs.96852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005717 ! EDC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004543 name: EDC4_human def: "Enhancer of mRNA-decapping protein 4 gene" [UniProtKB:Q6P2E9] synonym: "HEDLS" EXACT [UniProtKB:Q6P2E9] xref: EMBL:AK128582 xref: EMBL:BC043616 xref: EMBL:BC053598 xref: EMBL:BC064567 xref: EMBL:L26339 xref: EMBL:U17474 xref: HGNC:HGNC:17157 xref: UniGene:Hs.75682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005683 ! EDC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004545 name: EEF1A1_human def: "Elongation factor 1-alpha 1 gene" [UniProtKB:P68104] synonym: "EEF1A" EXACT [UniProtKB:P68104] synonym: "EF1A" EXACT [UniProtKB:P68104] synonym: "LENG7" EXACT [UniProtKB:P68104] xref: EMBL:AY043301 xref: EMBL:BC008587 xref: EMBL:BC009733 xref: EMBL:BC009875 xref: EMBL:BC010735 xref: EMBL:BC012891 xref: EMBL:BC014224 xref: EMBL:BC018150 xref: EMBL:BC018641 xref: EMBL:BC019669 xref: EMBL:BC021686 xref: EMBL:BC028674 xref: EMBL:BC038339 xref: EMBL:BC057391 xref: EMBL:BC066893 xref: EMBL:BC072385 xref: EMBL:BC082268 xref: EMBL:J04617 xref: EMBL:M29548 xref: EMBL:X03558 xref: EMBL:X03689 xref: EMBL:X16869 xref: HGNC:HGNC:3189 xref: UniGene:Hs.490287 xref: UniGene:Hs.520703 xref: UniGene:Hs.586423 xref: UniGene:Hs.644639 xref: UniGene:Hs.704732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005831 ! EF1A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004546 name: EEF1B2_human def: "Elongation factor 1-beta gene" [UniProtKB:P24534] synonym: "EEF1B" EXACT [UniProtKB:P24534] synonym: "EF1B" EXACT [UniProtKB:P24534] xref: EMBL:AC007383 xref: EMBL:BC000211 xref: EMBL:BC004931 xref: EMBL:BC067787 xref: EMBL:BT007079 xref: EMBL:CR456825 xref: EMBL:X60489 xref: EMBL:X60656 xref: HGNC:HGNC:3208 xref: UniGene:Hs.421608 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005752 ! EF1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004547 name: EEF1G_human def: "Elongation factor 1-gamma gene" [UniProtKB:P26641] synonym: "EF1G" EXACT [UniProtKB:P26641] synonym: "PRO1608" EXACT [UniProtKB:P26641] xref: EMBL:AF119850 xref: EMBL:BC000384 xref: EMBL:BC006509 xref: EMBL:BC006520 xref: EMBL:BC007949 xref: EMBL:BC009865 xref: EMBL:BC013918 xref: EMBL:BC015813 xref: EMBL:BC021974 xref: EMBL:BC028179 xref: EMBL:BC031012 xref: EMBL:BC067738 xref: EMBL:M55409 xref: EMBL:X63526 xref: EMBL:Z11531 xref: HGNC:HGNC:3213 xref: UniGene:Hs.144835 xref: UniGene:Hs.664670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006079 ! EF1G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004548 name: EFNA1_human def: "Ephrin-A1 precursor gene" [UniProtKB:P20827] synonym: "EPLG1" EXACT [UniProtKB:P20827] synonym: "LERK1" EXACT [UniProtKB:P20827] synonym: "TNFAIP4" EXACT [UniProtKB:P20827] xref: EMBL:AL691442 xref: EMBL:BC032698 xref: EMBL:BC095432 xref: EMBL:CR457416 xref: EMBL:M57730 xref: HGNC:HGNC:3221 xref: UniGene:Hs.516664 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006269 ! EFNA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004549 name: EFNB1_human def: "Ephrin-B1 precursor gene" [UniProtKB:P98172] synonym: "EFL-3" EXACT [UniProtKB:P98172] synonym: "EPLG2" EXACT [UniProtKB:P98172] synonym: "LERK2" EXACT [UniProtKB:P98172] xref: EMBL:AL136092 xref: EMBL:BC016649 xref: EMBL:BC052979 xref: EMBL:L37361 xref: EMBL:U09303 xref: EMBL:U09304 xref: HGNC:HGNC:3226 xref: UniGene:Hs.144700 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005815 ! EFNB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004550 name: EGFL6_human def: "EGF-like domain-containing protein 6 precursor gene" [UniProtKB:Q8IUX8] synonym: "MAEG" EXACT [UniProtKB:Q8IUX8] synonym: "PP648" EXACT [UniProtKB:Q8IUX8] synonym: "UNQ281/PRO320" EXACT [UniProtKB:Q8IUX8] xref: EMBL:AF186084 xref: EMBL:AF193055 xref: EMBL:AJ245671 xref: EMBL:AK075214 xref: EMBL:AL117610 xref: EMBL:AY358333 xref: EMBL:BC038587 xref: HGNC:HGNC:3235 xref: UniGene:Hs.12844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001947 ! EGFL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004551 name: EGFL7_human def: "EGF-like domain-containing protein 7 precursor gene" [UniProtKB:Q9UHF1] synonym: "MEGF7" EXACT [UniProtKB:Q9UHF1] synonym: "UNQ187/PRO1449" EXACT [UniProtKB:Q9UHF1] xref: EMBL:AB125649 xref: EMBL:AF186111 xref: EMBL:AL512735 xref: EMBL:AL590226 xref: EMBL:AY358901 xref: EMBL:AY358902 xref: EMBL:AY358903 xref: EMBL:BC012377 xref: EMBL:BC088371 xref: HGNC:HGNC:20594 xref: UniGene:Hs.91481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005958 ! EGFL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004552 name: EGFR_human def: "Epidermal growth factor receptor precursor gene" [UniProtKB:P00533] synonym: "ERBB1" EXACT [UniProtKB:P00533] xref: EMBL:AF125253 xref: EMBL:AF125538 xref: EMBL:AF125539 xref: EMBL:AF277897 xref: EMBL:AF288738 xref: EMBL:AY588246 xref: EMBL:M11234 xref: EMBL:M38425 xref: EMBL:U48722 xref: EMBL:U48723 xref: EMBL:U48724 xref: EMBL:U48725 xref: EMBL:U48726 xref: EMBL:U48727 xref: EMBL:U48728 xref: EMBL:U48729 xref: EMBL:U95089 xref: EMBL:X00588 xref: EMBL:X00663 xref: EMBL:X06370 xref: HGNC:HGNC:3236 xref: UniGene:Hs.488293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001462 ! EGFR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004553 name: EGF_human def: "Pro-epidermal growth factor precursor gene" [UniProtKB:P01133] xref: EMBL:AY506357 xref: EMBL:BC093731 xref: EMBL:BC113461 xref: EMBL:X04571 xref: HGNC:HGNC:3229 xref: UniGene:Hs.419815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001470 ! EGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004554 name: EGR2_human def: "Early growth response protein 2 gene" [UniProtKB:P11161] synonym: "KROX20" EXACT [UniProtKB:P11161] xref: EMBL:AF139463 xref: EMBL:AL133417 xref: EMBL:BC035625 xref: EMBL:CR749641 xref: EMBL:J04076 xref: EMBL:X53700 xref: HGNC:HGNC:3239 xref: UniGene:Hs.1395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006070 ! EGR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004555 name: EHMT1_human def: "Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 gene" [UniProtKB:Q9H9B1] synonym: "EUHMTASE1" EXACT [UniProtKB:Q9H9B1] synonym: "KIAA1876" EXACT [UniProtKB:Q9H9B1] synonym: "KMT1D" EXACT [UniProtKB:Q9H9B1] xref: EMBL:AB028932 xref: EMBL:AB058779 xref: EMBL:AK022941 xref: EMBL:AL590627 xref: EMBL:AL611925 xref: EMBL:AL713772 xref: EMBL:AY083210 xref: EMBL:BC011608 xref: HGNC:HGNC:24650 xref: UniGene:Hs.495511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006006 ! EHMT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004556 name: EIF2B3_human def: "Translation initiation factor eIF-2B subunit gamma gene" [UniProtKB:Q9NR50] xref: EMBL:AF257077 xref: EMBL:AK024006 xref: EMBL:AL136380 xref: EMBL:AL834288 xref: EMBL:BC018728 xref: HGNC:HGNC:3259 xref: UniGene:Hs.533549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005834 ! EI2BG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004557 name: EID1_human def: "EP300-interacting inhibitor of differentiation 1 gene" [UniProtKB:Q9Y6B2] synonym: "C15orf3" EXACT [UniProtKB:Q9Y6B2] synonym: "CRI1" EXACT [UniProtKB:Q9Y6B2] synonym: "PNAS-22" EXACT [UniProtKB:Q9Y6B2] synonym: "PTD014" EXACT [UniProtKB:Q9Y6B2] synonym: "RBP21" EXACT [UniProtKB:Q9Y6B2] xref: EMBL:AF092135 xref: EMBL:AF109873 xref: EMBL:AF274947 xref: EMBL:AF349444 xref: EMBL:AK098383 xref: EMBL:AL109701 xref: EMBL:AL357456 xref: EMBL:BC114944 xref: EMBL:BC114946 xref: HGNC:HGNC:1191 xref: UniGene:Hs.696128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002263 ! EID1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004558 name: ELF1_human def: "ETS-related transcription factor Elf-1 gene" [UniProtKB:P32519] xref: EMBL:AL157877 xref: EMBL:BC030507 xref: EMBL:CH471075 xref: EMBL:M82882 xref: HGNC:HGNC:3316 xref: UniGene:Hs.135646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006027 ! ELF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004559 name: ELK1_human def: "ETS domain-containing protein Elk-1 gene" [UniProtKB:P19419] xref: EMBL:AB016193 xref: EMBL:AB016194 xref: EMBL:AF000672 xref: EMBL:AF080616 xref: EMBL:AL009172 xref: EMBL:BC056150 xref: EMBL:M25269 xref: HGNC:HGNC:3321 xref: UniGene:Hs.701980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005637 ! ELK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004560 name: ELMO1_human def: "Engulfment and cell motility protein 1 gene" [UniProtKB:Q92556] synonym: "KIAA0281" EXACT [UniProtKB:Q92556] xref: EMBL:AF398885 xref: EMBL:AL136787 xref: EMBL:BC003051 xref: EMBL:BC064635 xref: EMBL:BC077074 xref: EMBL:BC114341 xref: EMBL:D87457 xref: HGNC:HGNC:16286 xref: UniGene:Hs.656638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005669 ! ELMO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004561 name: TCEB2_human def: "Transcription elongation factor B polypeptide 2 gene" [UniProtKB:Q15370] xref: EMBL:AC004493 xref: EMBL:BC013306 xref: EMBL:BC065000 xref: EMBL:L42856 xref: HGNC:HGNC:11619 xref: UniGene:Hs.172772 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005668 ! ELOB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004562 name: TCEB1_human def: "Transcription elongation factor B polypeptide 1 gene" [UniProtKB:Q15369] xref: EMBL:BC013809 xref: EMBL:BC093065 xref: EMBL:BC100028 xref: EMBL:BC100283 xref: EMBL:L34587 xref: HGNC:HGNC:11617 xref: UniGene:Hs.554594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005667 ! ELOC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004563 name: IKBKAP_human def: "Elongator complex protein 1 gene" [UniProtKB:O95163] synonym: "ELP1" EXACT [UniProtKB:O95163] synonym: "IKAP" EXACT [UniProtKB:O95163] xref: EMBL:AF044195 xref: EMBL:AF153419 xref: EMBL:AK001641 xref: EMBL:AK289962 xref: EMBL:AL049945 xref: EMBL:AL354797 xref: EMBL:AL359692 xref: EMBL:CH471105 xref: HGNC:HGNC:5959 xref: UniGene:Hs.494738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005398 ! ELP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004564 name: EML4_human def: "Echinoderm microtubule-associated protein-like 4 gene" [UniProtKB:Q9HC35] synonym: "C2orf2" EXACT [UniProtKB:Q9HC35] synonym: "EMAPL4" EXACT [UniProtKB:Q9HC35] xref: EMBL:AC006038 xref: EMBL:AC083949 xref: EMBL:AC096668 xref: EMBL:AF177377 xref: EMBL:AK001804 xref: EMBL:BC023522 xref: EMBL:BC104647 xref: HGNC:HGNC:1316 xref: UniGene:Hs.593614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002144 ! EMAL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004565 name: ENO1_human def: "Alpha-enolase gene" [UniProtKB:P06733] synonym: "ENO1L1" EXACT [UniProtKB:P06733] synonym: "MBPB1" EXACT [UniProtKB:P06733] synonym: "MPB1" EXACT [UniProtKB:P06733] xref: EMBL:AF035286 xref: EMBL:AL139415 xref: EMBL:AL833741 xref: EMBL:BC001810 xref: EMBL:BC004458 xref: EMBL:BC009912 xref: EMBL:BC011130 xref: EMBL:BC015641 xref: EMBL:BC021166 xref: EMBL:BC022545 xref: EMBL:BC027725 xref: EMBL:BC050642 xref: EMBL:BT007163 xref: EMBL:BX537400 xref: EMBL:DQ056744 xref: EMBL:M14328 xref: EMBL:M55914 xref: EMBL:U88968 xref: EMBL:X16288 xref: EMBL:X16289 xref: EMBL:X16290 xref: EMBL:X84907 xref: HGNC:HGNC:3350 xref: UniGene:Hs.517145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005779 ! ENOA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004566 name: ENO2_human def: "Gamma-enolase gene" [UniProtKB:P09104] xref: EMBL:BC002745 xref: EMBL:BT007383 xref: EMBL:M22349 xref: EMBL:M36768 xref: EMBL:U47924 xref: EMBL:X13120 xref: EMBL:X14327 xref: EMBL:X51956 xref: HGNC:HGNC:3353 xref: UniGene:Hs.511915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006270 ! ENOG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004567 name: EPS15_human def: "Epidermal growth factor receptor substrate 15 gene" [UniProtKB:P42566] synonym: "AF1P" EXACT [UniProtKB:P42566] xref: EMBL:AC104170 xref: EMBL:AL671986 xref: EMBL:DQ367924 xref: EMBL:U07707 xref: EMBL:Z29064 xref: HGNC:HGNC:3419 xref: UniGene:Hs.83722 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005424 ! EP15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004568 name: EP300_human def: "Histone acetyltransferase p300 gene" [UniProtKB:Q09472] synonym: "P300" EXACT [UniProtKB:Q09472] xref: EMBL:U01877 xref: HGNC:HGNC:3373 xref: UniGene:Hs.517517 xref: UniGene:Hs.655211 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001728 ! EP300_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004569 name: EP400_human def: "E1A-binding protein p400 gene" [UniProtKB:Q96L91] synonym: "CAGH32" EXACT [UniProtKB:Q96L91] synonym: "KIAA1498" EXACT [UniProtKB:Q96L91] synonym: "KIAA1818" EXACT [UniProtKB:Q96L91] synonym: "TNRC12" EXACT [UniProtKB:Q96L91] xref: EMBL:AB040931 xref: EMBL:AB058721 xref: EMBL:AC137590 xref: EMBL:AC137632 xref: EMBL:AK096311 xref: EMBL:AY044869 xref: EMBL:BC037208 xref: EMBL:BC064554 xref: EMBL:U80743 xref: HGNC:HGNC:11958 xref: UniGene:Hs.699245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005916 ! EP400_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004570 name: EPAS1_human def: "Endothelial PAS domain-containing protein 1 gene" [UniProtKB:Q99814] synonym: "HIF2A" EXACT [UniProtKB:Q99814] synonym: "MOP2" EXACT [UniProtKB:Q99814] xref: EMBL:BC051338 xref: EMBL:U51626 xref: EMBL:U81984 xref: HGNC:HGNC:3374 xref: UniGene:Hs.468410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006077 ! EPAS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004571 name: EPC1_human def: "Enhancer of polycomb homolog 1 gene" [UniProtKB:Q9H2F5] xref: EMBL:AF277374 xref: EMBL:AF286905 xref: EMBL:AK024329 xref: EMBL:AK092304 xref: EMBL:AL158834 xref: EMBL:AL391839 xref: EMBL:BC036529 xref: HGNC:HGNC:19876 xref: UniGene:Hs.167805 xref: UniGene:Hs.633485 xref: UniGene:Hs.654496 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005369 ! EPC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004572 name: EPC2_human def: "Enhancer of polycomb homolog 2 gene" [UniProtKB:Q52LR7] xref: EMBL:AF286904 xref: EMBL:AK001433 xref: EMBL:AK002010 xref: EMBL:AL117558 xref: EMBL:BC093818 xref: EMBL:BC093820 xref: HGNC:HGNC:24543 xref: UniGene:Hs.23270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005371 ! EPC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004573 name: EPHA2_human def: "Ephrin type-A receptor 2 precursor gene" [UniProtKB:P29317] synonym: "ECK" EXACT [UniProtKB:P29317] xref: EMBL:AL451042 xref: EMBL:BC037166 xref: EMBL:CH471167 xref: EMBL:M59371 xref: HGNC:HGNC:3386 xref: UniGene:Hs.171596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005832 ! EPHA2_HUMAN relationship: codes_for CCO:B0014960 ! Q8N3Z2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004574 name: EPHB2_human def: "Ephrin type-B receptor 2 precursor gene" [UniProtKB:P29323] synonym: "DRT" EXACT [UniProtKB:P29323] synonym: "EPHT3" EXACT [UniProtKB:P29323] synonym: "EPTH3" EXACT [UniProtKB:P29323] synonym: "ERK" EXACT [UniProtKB:P29323] synonym: "HEK5" EXACT [UniProtKB:P29323] synonym: "TYRO5" EXACT [UniProtKB:P29323] xref: EMBL:AF025304 xref: EMBL:AL035704 xref: EMBL:AL158086 xref: EMBL:AL512444 xref: EMBL:D14717 xref: EMBL:D31661 xref: EMBL:D37827 xref: EMBL:L36643 xref: EMBL:L41939 xref: EMBL:X59292 xref: HGNC:HGNC:3393 xref: UniGene:Hs.523329 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001568 ! EPHB2_HUMAN relationship: codes_for CCO:B0048923 ! B1AKC9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004575 name: EPHB4_human def: "Ephrin type-B receptor 4 precursor gene" [UniProtKB:P54760] synonym: "HTK" EXACT [UniProtKB:P54760] synonym: "TYRO11" EXACT [UniProtKB:P54760] xref: EMBL:AF312032 xref: EMBL:AY056048 xref: EMBL:BC004264 xref: EMBL:CH471091 xref: EMBL:U07695 xref: HGNC:HGNC:3395 xref: UniGene:Hs.437008 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005833 ! EPHB4_HUMAN relationship: codes_for CCO:B0014956 ! Q96L35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004576 name: EPHB6_human def: "Ephrin type-B receptor 6 precursor gene" [UniProtKB:O15197] xref: EMBL:AF107256 xref: EMBL:AY280502 xref: EMBL:D83492 xref: HGNC:HGNC:3396 xref: UniGene:Hs.380089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006024 ! EPHB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004577 name: ERBB2_human def: "Receptor tyrosine-protein kinase erbB-2 precursor gene" [UniProtKB:P04626] synonym: "HER2" EXACT [UniProtKB:P04626] synonym: "NEU" EXACT [UniProtKB:P04626] synonym: "NGL" EXACT [UniProtKB:P04626] xref: EMBL:AY208911 xref: EMBL:L29395 xref: EMBL:M11730 xref: EMBL:M11761 xref: EMBL:M11762 xref: EMBL:M11763 xref: EMBL:M11764 xref: EMBL:M11765 xref: EMBL:M11766 xref: EMBL:M11767 xref: EMBL:M12036 xref: EMBL:M16789 xref: EMBL:M16790 xref: EMBL:M16791 xref: EMBL:M16792 xref: EMBL:M95667 xref: EMBL:X03363 xref: HGNC:HGNC:3430 xref: UniGene:Hs.446352 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005540 ! ERBB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004578 name: ERBB3_human def: "Receptor tyrosine-protein kinase erbB-3 precursor gene" [UniProtKB:P21860] synonym: "HER3" EXACT [UniProtKB:P21860] xref: EMBL:BC002706 xref: EMBL:BC082992 xref: EMBL:BT007226 xref: EMBL:M29366 xref: EMBL:M34309 xref: EMBL:S61953 xref: HGNC:HGNC:3431 xref: UniGene:Hs.118681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005852 ! ERBB3_HUMAN relationship: codes_for CCO:B0018701 ! Q9BUD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004579 name: ERBB4_human def: "Receptor tyrosine-protein kinase erbB-4 precursor gene" [UniProtKB:Q15303] synonym: "HER4" EXACT [UniProtKB:Q15303] xref: EMBL:AB209697 xref: EMBL:BC112199 xref: EMBL:L07868 xref: HGNC:HGNC:3432 xref: UniGene:Hs.390729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005906 ! ERBB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004580 name: ERCC5_human def: "DNA repair protein complementing XP-G cells gene" [UniProtKB:P28715] synonym: "ERCM2" EXACT [UniProtKB:P28715] synonym: "XPG" EXACT [UniProtKB:P28715] synonym: "XPGC" EXACT [UniProtKB:P28715] xref: EMBL:AF255431 xref: EMBL:AF255433 xref: EMBL:AF255434 xref: EMBL:AF255435 xref: EMBL:AF255436 xref: EMBL:AF255437 xref: EMBL:AF255438 xref: EMBL:AF255439 xref: EMBL:AF255440 xref: EMBL:AF255441 xref: EMBL:AF255442 xref: EMBL:AF462447 xref: EMBL:AF550128 xref: EMBL:AL157769 xref: EMBL:BC031522 xref: EMBL:D16305 xref: EMBL:L20046 xref: EMBL:X69978 xref: EMBL:X71341 xref: EMBL:X71342 xref: HGNC:HGNC:3437 xref: UniGene:Hs.258429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006036 ! ERCC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004581 name: EREG_human def: "Proepiregulin precursor gene" [UniProtKB:O14944] xref: EMBL:CR541887 xref: EMBL:D30783 xref: HGNC:HGNC:3443 xref: UniGene:Hs.115263 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001362 ! EREG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004582 name: ERF_human def: "ETS domain-containing transcription factor ERF gene" [UniProtKB:P50548] xref: EMBL:AB209271 xref: EMBL:AC006486 xref: EMBL:AK314278 xref: EMBL:BC022231 xref: EMBL:CH471126 xref: EMBL:U15655 xref: HGNC:HGNC:3444 xref: UniGene:Hs.655969 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001642 ! ERF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004583 name: C14orf1_human def: "Probable ergosterol biosynthetic protein 28 gene" [UniProtKB:Q9UKR5] synonym: "AD-011" EXACT [UniProtKB:Q9UKR5] synonym: "HSPC288" EXACT [UniProtKB:Q9UKR5] synonym: "x0006" EXACT [UniProtKB:Q9UKR5] xref: EMBL:AC007182 xref: EMBL:AF134159 xref: EMBL:AF136971 xref: EMBL:AF161406 xref: EMBL:AL136658 xref: EMBL:BC002444 xref: HGNC:HGNC:1187 xref: UniGene:Hs.702044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006287 ! ERG28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004584 name: ERH_human def: "Enhancer of rudimentary homolog gene" [UniProtKB:P84090] xref: EMBL:BC014301 xref: EMBL:BC071709 xref: EMBL:BT006877 xref: EMBL:CR450298 xref: EMBL:CR542178 xref: EMBL:D85758 xref: EMBL:U66871 xref: HGNC:HGNC:3447 xref: UniGene:Hs.509791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001703 ! ERH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004585 name: ERN1_human def: "Serine/threonine-protein kinase/endoribonuclease IRE1 precursor gene" [UniProtKB:O75460] synonym: "IRE1" EXACT [UniProtKB:O75460] xref: EMBL:AB209869 xref: EMBL:AC005803 xref: EMBL:AC025362 xref: EMBL:AF059198 xref: EMBL:AK292403 xref: EMBL:BC130405 xref: EMBL:BC130407 xref: EMBL:BI912495 xref: EMBL:CH471109 xref: EMBL:DA254477 xref: HGNC:HGNC:3449 xref: UniGene:Hs.133982 xref: UniGene:Hs.356481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001428 ! ERN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004586 name: ERN2_human def: "Serine/threonine-protein kinase/endoribonuclease IRE2 precursor gene" [UniProtKB:Q76MJ5] synonym: "IRE2" EXACT [UniProtKB:Q76MJ5] xref: EMBL:AB047079 xref: EMBL:AK131280 xref: HGNC:HGNC:16942 xref: UniGene:Hs.592041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001928 ! ERN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004587 name: ESCO1_human def: "N-acetyltransferase ESCO1 gene" [UniProtKB:Q5FWF5] synonym: "EFO1" EXACT [UniProtKB:Q5FWF5] synonym: "KIAA1911" EXACT [UniProtKB:Q5FWF5] xref: EMBL:AB067498 xref: EMBL:AK090579 xref: EMBL:AL832041 xref: EMBL:AL834200 xref: EMBL:BC036943 xref: EMBL:BC089426 xref: EMBL:BK001617 xref: HGNC:HGNC:24645 xref: UniGene:Hs.464733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001848 ! ESCO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004588 name: ESCO2_human def: "N-acetyltransferase ESCO2 gene" [UniProtKB:Q56NI9] xref: EMBL:AY882862 xref: HGNC:HGNC:27230 xref: UniGene:Hs.99480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001841 ! ESCO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004589 name: ESPL1_human def: "Separin gene" [UniProtKB:Q14674] synonym: "ESP1" EXACT [UniProtKB:Q14674] synonym: "KIAA0165" EXACT [UniProtKB:Q14674] xref: EMBL:AY455930 xref: EMBL:D79987 xref: HGNC:HGNC:16856 xref: UniGene:Hs.153479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001787 ! ESPL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004590 name: ESR1_human def: "Estrogen receptor gene" [UniProtKB:P03372] synonym: "ESR" EXACT [UniProtKB:P03372] synonym: "NR3A1" EXACT [UniProtKB:P03372] xref: EMBL:AF123494 xref: EMBL:AF123495 xref: EMBL:AF123496 xref: EMBL:AF123497 xref: EMBL:AF123498 xref: EMBL:AF123499 xref: EMBL:AF123500 xref: EMBL:AL049821 xref: EMBL:AL078582 xref: EMBL:AL356311 xref: EMBL:AL590993 xref: EMBL:AY425004 xref: EMBL:DQ163909 xref: EMBL:M12674 xref: EMBL:U47678 xref: EMBL:X03635 xref: EMBL:X73067 xref: EMBL:Z75126 xref: HGNC:HGNC:3467 xref: UniGene:Hs.208124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005652 ! ESR1_HUMAN relationship: codes_for CCO:B0030141 ! Q0H8T6_HUMAN relationship: codes_for CCO:B0054175 ! B0QYW7_HUMAN relationship: codes_for CCO:B0056583 ! Q5T5H8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004591 name: ETHE1_human def: "Protein ETHE1, mitochondrial precursor gene" [UniProtKB:O95571] synonym: "HSCO" EXACT [UniProtKB:O95571] xref: EMBL:AC018758 xref: EMBL:BC008250 xref: EMBL:D83198 xref: HGNC:HGNC:23287 xref: UniGene:Hs.7486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006189 ! ETHE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004592 name: EVI5_human def: "Ecotropic viral integration site 5 protein homolog gene" [UniProtKB:O60447] synonym: "NB4S" EXACT [UniProtKB:O60447] xref: EMBL:AC104332 xref: EMBL:AC104456 xref: EMBL:AF008915 xref: EMBL:AL133332 xref: EMBL:AL354890 xref: HGNC:HGNC:3501 xref: UniGene:Hs.656836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001408 ! EVI5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004593 name: EWSR1_human def: "RNA-binding protein EWS gene" [UniProtKB:Q01844] synonym: "EWS" EXACT [UniProtKB:Q01844] xref: EMBL:AB016435 xref: EMBL:BC004817 xref: EMBL:X66899 xref: EMBL:X72990 xref: EMBL:X72991 xref: EMBL:X72992 xref: EMBL:X72993 xref: EMBL:X72994 xref: EMBL:X72995 xref: EMBL:X72996 xref: EMBL:X72997 xref: EMBL:X72998 xref: EMBL:X72999 xref: EMBL:X73000 xref: EMBL:X73001 xref: EMBL:X73002 xref: EMBL:X73003 xref: EMBL:X73004 xref: EMBL:Y07848 xref: EMBL:Y08806 xref: HGNC:HGNC:3508 xref: UniGene:Hs.374477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005225 ! EWS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004594 name: EXO1_human def: "Exonuclease 1 gene" [UniProtKB:Q9UQ84] synonym: "EXOI" EXACT [UniProtKB:Q9UQ84] synonym: "HEX1" EXACT [UniProtKB:Q9UQ84] xref: EMBL:AC004783 xref: EMBL:AF042282 xref: EMBL:AF060479 xref: EMBL:AF084974 xref: EMBL:AF091740 xref: EMBL:AF091742 xref: EMBL:AF091743 xref: EMBL:AF091744 xref: EMBL:AF091745 xref: EMBL:AF091746 xref: EMBL:AF091747 xref: EMBL:AF091748 xref: EMBL:AF091749 xref: EMBL:AF091750 xref: EMBL:AF091751 xref: EMBL:AF091752 xref: EMBL:AF091753 xref: EMBL:AF091754 xref: EMBL:AF549168 xref: EMBL:AL080139 xref: EMBL:AL365366 xref: EMBL:BC007491 xref: HGNC:HGNC:3511 xref: UniGene:Hs.498248 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002240 ! EXO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004595 name: EXOC1_human def: "Exocyst complex component 1 gene" [UniProtKB:Q9NV70] synonym: "BM-012" EXACT [UniProtKB:Q9NV70] synonym: "SEC3" EXACT [UniProtKB:Q9NV70] synonym: "SEC3L1" EXACT [UniProtKB:Q9NV70] xref: EMBL:AF208854 xref: EMBL:AK001755 xref: EMBL:AK027413 xref: EMBL:BC020650 xref: EMBL:BC094751 xref: HGNC:HGNC:30380 xref: UniGene:Hs.269665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005592 ! EXOC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004596 name: EXOC8_human def: "Exocyst complex component 8 gene" [UniProtKB:Q8IYI6] xref: EMBL:AL117352 xref: EMBL:BC035763 xref: HGNC:HGNC:24659 xref: UniGene:Hs.356198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005255 ! EXOC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004597 name: EXOSC3_human def: "Exosome complex exonuclease RRP40 gene" [UniProtKB:Q9NQT5] synonym: "CGI-102" EXACT [UniProtKB:Q9NQT5] synonym: "RRP40" EXACT [UniProtKB:Q9NQT5] xref: EMBL:AF151860 xref: EMBL:AF281132 xref: EMBL:BC002437 xref: EMBL:BC008880 xref: HGNC:HGNC:17944 xref: UniGene:Hs.591076 xref: UniGene:Hs.602571 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005557 ! EXOS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004598 name: EXOSC4_human def: "Exosome complex exonuclease RRP41 gene" [UniProtKB:Q9NPD3] synonym: "RRP41" EXACT [UniProtKB:Q9NPD3] synonym: "SKI6" EXACT [UniProtKB:Q9NPD3] xref: EMBL:AF281133 xref: EMBL:AK000598 xref: EMBL:BC002777 xref: HGNC:HGNC:18189 xref: UniGene:Hs.632041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005554 ! EXOS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004599 name: EXOSC5_human def: "Exosome complex exonuclease RRP46 gene" [UniProtKB:Q9NQT4] synonym: "CML28" EXACT [UniProtKB:Q9NQT4] synonym: "RRP46" EXACT [UniProtKB:Q9NQT4] xref: EMBL:AF281134 xref: EMBL:AF285785 xref: EMBL:BC007742 xref: EMBL:BC107696 xref: HGNC:HGNC:24662 xref: UniGene:Hs.283741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005555 ! EXOS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004600 name: EXOSC8_human def: "Exosome complex exonuclease RRP43 gene" [UniProtKB:Q96B26] synonym: "OIP2" EXACT [UniProtKB:Q96B26] synonym: "RRP43" EXACT [UniProtKB:Q96B26] xref: EMBL:AF025438 xref: EMBL:AL138706 xref: EMBL:BC020773 xref: EMBL:CH471075 xref: HGNC:HGNC:17035 xref: UniGene:Hs.294041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005556 ! EXOS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004601 name: EXOSC10_human def: "Exosome component 10 gene" [UniProtKB:Q01780] synonym: "PMSCL" EXACT [UniProtKB:Q01780] synonym: "PMSCL2" EXACT [UniProtKB:Q01780] xref: EMBL:AJ300188 xref: EMBL:AL109811 xref: EMBL:BC039901 xref: EMBL:BC073788 xref: EMBL:L01457 xref: EMBL:X66113 xref: HGNC:HGNC:9138 xref: UniGene:Hs.632368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005348 ! EXOSX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004602 name: EXT1_human def: "Exostosin-1 gene" [UniProtKB:Q16394] xref: EMBL:BC001174 xref: EMBL:S79639 xref: EMBL:U70539 xref: HGNC:HGNC:3512 xref: UniGene:Hs.492618 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001818 ! EXT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004603 name: EXT2_human def: "Exostosin-2 gene" [UniProtKB:Q93063] xref: EMBL:BC010058 xref: EMBL:U62740 xref: EMBL:U64511 xref: EMBL:U67356 xref: EMBL:U67357 xref: EMBL:U67358 xref: EMBL:U67360 xref: EMBL:U67361 xref: EMBL:U67362 xref: EMBL:U67363 xref: EMBL:U67364 xref: EMBL:U67365 xref: EMBL:U67366 xref: EMBL:U67367 xref: EMBL:U67368 xref: EMBL:U72263 xref: HGNC:HGNC:3513 xref: UniGene:Hs.368404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002028 ! EXT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004604 name: FAM131C_human def: "Protein FAM131C gene" [UniProtKB:Q96AQ9] synonym: "C1orf117" EXACT [UniProtKB:Q96AQ9] xref: EMBL:AK094085 xref: EMBL:AL355994 xref: EMBL:BC016848 xref: EMBL:BC037394 xref: HGNC:HGNC:26717 xref: UniGene:Hs.126825 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005290 ! F131C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004605 name: FANCD2_human def: "Fanconi anemia group D2 protein gene" [UniProtKB:Q9BXW9] synonym: "FACD" EXACT [UniProtKB:Q9BXW9] xref: EMBL:AF230336 xref: EMBL:AF273222 xref: EMBL:AF273223 xref: EMBL:AF273224 xref: EMBL:AF273225 xref: EMBL:AF273226 xref: EMBL:AF273227 xref: EMBL:AF273228 xref: EMBL:AF273229 xref: EMBL:AF273230 xref: EMBL:AF273231 xref: EMBL:AF273232 xref: EMBL:AF273233 xref: EMBL:AF273234 xref: EMBL:AF273235 xref: EMBL:AF273236 xref: EMBL:AF273237 xref: EMBL:AF273238 xref: EMBL:AF273239 xref: EMBL:AF273240 xref: EMBL:AF273241 xref: EMBL:AF273242 xref: EMBL:AF273243 xref: EMBL:AF273244 xref: EMBL:AF273245 xref: EMBL:AF273246 xref: EMBL:AF273247 xref: EMBL:AF273248 xref: EMBL:AF273249 xref: EMBL:AF273250 xref: EMBL:AF273251 xref: EMBL:AF340183 xref: EMBL:AK022613 xref: EMBL:AL832427 xref: EMBL:BC013582 xref: EMBL:DQ341263 xref: HGNC:HGNC:3585 xref: UniGene:Hs.208388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002109 ! FACD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004606 name: PTK2_human def: "Focal adhesion kinase 1 gene" [UniProtKB:Q05397] synonym: "FAK" EXACT [UniProtKB:Q05397] synonym: "FAK1" EXACT [UniProtKB:Q05397] xref: EMBL:AC067931 xref: EMBL:BC035404 xref: EMBL:L05186 xref: EMBL:L13616 xref: HGNC:HGNC:9611 xref: UniGene:Hs.395482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005812 ! FAK1_HUMAN relationship: codes_for CCO:B0054133 ! A8MYY5_HUMAN relationship: codes_for CCO:B0057392 ! Q8IYN9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004607 name: PTK2B_human def: "Protein tyrosine kinase 2 beta gene" [UniProtKB:Q14289] synonym: "FAK2" EXACT [UniProtKB:Q14289] synonym: "PYK2" EXACT [UniProtKB:Q14289] synonym: "RAFTK" EXACT [UniProtKB:Q14289] xref: EMBL:AF311103 xref: EMBL:BC042599 xref: EMBL:D45853 xref: EMBL:L49207 xref: EMBL:S80542 xref: EMBL:U33284 xref: EMBL:U43522 xref: HGNC:HGNC:9612 xref: UniGene:Hs.491322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005846 ! FAK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004608 name: FANCA_human def: "Fanconi anemia group A protein gene" [UniProtKB:O15360] synonym: "FAA" EXACT [UniProtKB:O15360] synonym: "FACA" EXACT [UniProtKB:O15360] synonym: "FANCH" EXACT [UniProtKB:O15360] xref: EMBL:AC005360 xref: EMBL:AC005565 xref: EMBL:AC005567 xref: EMBL:AC092385 xref: EMBL:AF054569 xref: EMBL:AJ225084 xref: EMBL:AJ225085 xref: EMBL:AY598423 xref: EMBL:BC008979 xref: EMBL:X99226 xref: EMBL:Z83067 xref: EMBL:Z83068 xref: EMBL:Z83069 xref: EMBL:Z83070 xref: EMBL:Z83071 xref: EMBL:Z83072 xref: EMBL:Z83073 xref: EMBL:Z83074 xref: EMBL:Z83075 xref: EMBL:Z83076 xref: EMBL:Z83077 xref: EMBL:Z83078 xref: EMBL:Z83079 xref: EMBL:Z83080 xref: EMBL:Z83081 xref: EMBL:Z83082 xref: EMBL:Z83083 xref: EMBL:Z83084 xref: EMBL:Z83085 xref: EMBL:Z83086 xref: EMBL:Z83087 xref: EMBL:Z83088 xref: EMBL:Z83089 xref: EMBL:Z83090 xref: EMBL:Z83091 xref: EMBL:Z83092 xref: EMBL:Z83093 xref: EMBL:Z83094 xref: EMBL:Z83095 xref: EMBL:Z83151 xref: HGNC:HGNC:3582 xref: UniGene:Hs.567267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005323 ! FANCA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004609 name: FANCE_human def: "Fanconi anemia group E protein gene" [UniProtKB:Q9HB96] synonym: "FACE" EXACT [UniProtKB:Q9HB96] xref: EMBL:AF265210 xref: EMBL:AL022721 xref: EMBL:BC046359 xref: EMBL:DQ020173 xref: HGNC:HGNC:3586 xref: UniGene:Hs.302003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005576 ! FANCE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004610 name: FANCF_human def: "Fanconi anemia group F protein gene" [UniProtKB:Q9NPI8] xref: EMBL:AF181994 xref: EMBL:AF181995 xref: EMBL:AK023153 xref: EMBL:AY928335 xref: EMBL:BC047028 xref: EMBL:BC093867 xref: EMBL:BC101807 xref: HGNC:HGNC:3587 xref: UniGene:Hs.632151 xref: UniGene:Hs.702150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005936 ! FANCF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004611 name: FANCG_human def: "Fanconi anemia group G protein gene" [UniProtKB:O15287] synonym: "XRCC9" EXACT [UniProtKB:O15287] xref: EMBL:AC004472 xref: EMBL:AJ007669 xref: EMBL:AL353795 xref: EMBL:AY795970 xref: EMBL:BC000032 xref: EMBL:BC011623 xref: EMBL:U70310 xref: HGNC:HGNC:3588 xref: UniGene:Hs.591084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001370 ! FANCG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004612 name: FANCI_human def: "Fanconi anemia group I protein gene" [UniProtKB:Q9NVI1] synonym: "KIAA1794" EXACT [UniProtKB:Q9NVI1] xref: EMBL:AB058697 xref: EMBL:AC124068 xref: EMBL:AK001581 xref: EMBL:AK027564 xref: EMBL:BC004277 xref: EMBL:BC140769 xref: EMBL:EF567077 xref: HGNC:HGNC:25568 xref: UniGene:Hs.513126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002170 ! FANCI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004613 name: BRIP1_human def: "Fanconi anemia group J protein gene" [UniProtKB:Q9BX63] synonym: "BACH1" EXACT [UniProtKB:Q9BX63] synonym: "FANCJ" EXACT [UniProtKB:Q9BX63] xref: EMBL:AF360549 xref: EMBL:AK074713 xref: EMBL:BC101472 xref: EMBL:BC101474 xref: HGNC:HGNC:20473 xref: UniGene:Hs.532799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002107 ! FANCJ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004614 name: FBLN1_human def: "Fibulin-1 precursor gene" [UniProtKB:P23142] synonym: "PP213" EXACT [UniProtKB:P23142] xref: EMBL:AF126110 xref: EMBL:AF217999 xref: EMBL:AL021391 xref: EMBL:AY040589 xref: EMBL:BC022497 xref: EMBL:U01244 xref: EMBL:X53741 xref: EMBL:X53742 xref: EMBL:X53743 xref: EMBL:Z95331 xref: EMBL:Z98047 xref: HGNC:HGNC:3600 xref: UniGene:Hs.24601 xref: UniGene:Hs.593123 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005959 ! FBLN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004615 name: EFEMP1_human def: "EGF-containing fibulin-like extracellular matrix protein 1 precursor gene" [UniProtKB:Q12805] synonym: "FBLN3" EXACT [UniProtKB:Q12805] synonym: "FBNL" EXACT [UniProtKB:Q12805] xref: EMBL:AY004321 xref: EMBL:AY004322 xref: EMBL:AY004323 xref: EMBL:AY004324 xref: EMBL:AY004325 xref: EMBL:AY004326 xref: EMBL:AY004327 xref: EMBL:AY004328 xref: EMBL:AY004329 xref: EMBL:AY004330 xref: EMBL:BC014410 xref: EMBL:BC098561 xref: EMBL:U03877 xref: HGNC:HGNC:3218 xref: UniGene:Hs.76224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005955 ! FBLN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004616 name: EFEMP2_human def: "EGF-containing fibulin-like extracellular matrix protein 2 precursor gene" [UniProtKB:O95967] synonym: "FBLN4" EXACT [UniProtKB:O95967] synonym: "UNQ200/PRO226" EXACT [UniProtKB:O95967] xref: EMBL:AF093119 xref: EMBL:AF109121 xref: EMBL:AJ132819 xref: EMBL:AP001201 xref: EMBL:AY358899 xref: EMBL:BC010456 xref: HGNC:HGNC:3219 xref: UniGene:Hs.647231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005215 ! FBLN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004617 name: FBLN5_human def: "Fibulin-5 precursor gene" [UniProtKB:Q9UBX5] synonym: "DANCE" EXACT [UniProtKB:Q9UBX5] synonym: "UNQ184/PRO210" EXACT [UniProtKB:Q9UBX5] xref: EMBL:AF093118 xref: EMBL:AF112152 xref: EMBL:AJ133490 xref: EMBL:AY358898 xref: EMBL:BC022280 xref: HGNC:HGNC:3602 xref: UniGene:Hs.332708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005989 ! FBLN5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004618 name: FBL_human def: "rRNA 2'-O-methyltransferase fibrillarin gene" [UniProtKB:P22087] synonym: "FIB1" EXACT [UniProtKB:P22087] synonym: "FLRN" EXACT [UniProtKB:P22087] xref: EMBL:AC005393 xref: EMBL:AC006950 xref: EMBL:BC019260 xref: EMBL:BT006830 xref: EMBL:BT020144 xref: EMBL:CR457069 xref: EMBL:M59849 xref: EMBL:X56597 xref: HGNC:HGNC:3599 xref: UniGene:Hs.299002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005722 ! FBRL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004619 name: BTRC_human def: "F-box/WD repeat-containing protein 1A gene" [UniProtKB:Q9Y297] synonym: "BTRCP" EXACT [UniProtKB:Q9Y297] synonym: "FBW1A" EXACT [UniProtKB:Q9Y297] synonym: "FBXW1A" EXACT [UniProtKB:Q9Y297] xref: EMBL:AF101784 xref: EMBL:AF129530 xref: EMBL:BC027994 xref: EMBL:Y14153 xref: HGNC:HGNC:1144 xref: UniGene:Hs.696242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005633 ! FBW1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004620 name: FBXW11_human def: "F-box/WD repeat-containing protein 11 gene" [UniProtKB:Q9UKB1] synonym: "BTRCP2" EXACT [UniProtKB:Q9UKB1] synonym: "FBW1B" EXACT [UniProtKB:Q9UKB1] synonym: "FBXW1B" EXACT [UniProtKB:Q9UKB1] synonym: "KIAA0696" EXACT [UniProtKB:Q9UKB1] xref: EMBL:AB014596 xref: EMBL:AB033279 xref: EMBL:AB033280 xref: EMBL:AB033281 xref: EMBL:AF176022 xref: EMBL:BC026213 xref: HGNC:HGNC:13607 xref: UniGene:Hs.484138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005941 ! FBW1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004621 name: FBXO11_human def: "F-box only protein 11 gene" [UniProtKB:Q86XK2] synonym: "FBX11" EXACT [UniProtKB:Q86XK2] synonym: "UG063H01" EXACT [UniProtKB:Q86XK2] synonym: "VIT1" EXACT [UniProtKB:Q86XK2] xref: EMBL:AC006509 xref: EMBL:AC079807 xref: EMBL:AF174599 xref: EMBL:AF176706 xref: EMBL:AF264714 xref: EMBL:AF351618 xref: EMBL:AK022735 xref: EMBL:AK025477 xref: EMBL:AK223592 xref: EMBL:AL117620 xref: EMBL:AY827075 xref: EMBL:BC012728 xref: EMBL:BC043258 xref: HGNC:HGNC:13590 xref: UniGene:Hs.352677 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005332 ! FBX11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004622 name: FBXO18_human def: "F-box only protein 18 gene" [UniProtKB:Q8NFZ0] synonym: "FBH1" EXACT [UniProtKB:Q8NFZ0] synonym: "FBX18" EXACT [UniProtKB:Q8NFZ0] xref: EMBL:AF380349 xref: EMBL:AF454502 xref: EMBL:AF456237 xref: EMBL:AK027381 xref: EMBL:AK027496 xref: EMBL:AK095343 xref: EMBL:AL133069 xref: EMBL:AL137186 xref: EMBL:BC012762 xref: EMBL:BC032674 xref: EMBL:BC113377 xref: HGNC:HGNC:13620 xref: UniGene:Hs.498543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006328 ! FBX18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004623 name: FBXO25_human def: "F-box only protein 25 gene" [UniProtKB:Q8TCJ0] synonym: "FBX25" EXACT [UniProtKB:Q8TCJ0] xref: EMBL:AB070270 xref: EMBL:AF174605 xref: EMBL:AF419858 xref: EMBL:BC020249 xref: EMBL:BC050393 xref: HGNC:HGNC:13596 xref: UniGene:Hs.438454 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005440 ! FBX25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004624 name: FBXO43_human def: "F-box only protein 43 gene" [UniProtKB:Q4G163] synonym: "EMI2" EXACT [UniProtKB:Q4G163] xref: EMBL:AC021590 xref: HGNC:HGNC:28521 xref: UniGene:Hs.339577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001835 ! FBX43_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004625 name: FBXO4_human def: "F-box only protein 4 gene" [UniProtKB:Q9UKT5] synonym: "FBX4" EXACT [UniProtKB:Q9UKT5] xref: EMBL:AF129534 xref: EMBL:AF176703 xref: EMBL:BC048098 xref: EMBL:CR749719 xref: HGNC:HGNC:13583 xref: UniGene:Hs.165575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005441 ! FBX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004626 name: FBXO5_human def: "F-box only protein 5 gene" [UniProtKB:Q9UKT4] synonym: "EMI1" EXACT [UniProtKB:Q9UKT4] synonym: "FBX5" EXACT [UniProtKB:Q9UKT4] xref: EMBL:AF129535 xref: EMBL:AL080276 xref: EMBL:AY079515 xref: EMBL:BC018905 xref: HGNC:HGNC:13584 xref: UniGene:Hs.705509 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002221 ! FBX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004627 name: FBXO7_human def: "F-box only protein 7 gene" [UniProtKB:Q9Y3I1] synonym: "FBX7" EXACT [UniProtKB:Q9Y3I1] xref: EMBL:AF129537 xref: EMBL:AF233225 xref: EMBL:AL021937 xref: EMBL:AL035068 xref: EMBL:AL050254 xref: EMBL:BC008361 xref: EMBL:CR456491 xref: EMBL:Z71183 xref: HGNC:HGNC:13586 xref: UniGene:Hs.5912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005442 ! FBX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004628 name: FBXW7_human def: "F-box/WD repeat-containing protein 7 gene" [UniProtKB:Q969H0] synonym: "FBW7" EXACT [UniProtKB:Q969H0] synonym: "FBX30" EXACT [UniProtKB:Q969H0] synonym: "SEL10" EXACT [UniProtKB:Q969H0] xref: EMBL:AF383178 xref: EMBL:AF411971 xref: EMBL:AF411972 xref: EMBL:AK001933 xref: EMBL:AY008274 xref: EMBL:AY033553 xref: EMBL:AY049984 xref: EMBL:BC037320 xref: EMBL:BC117244 xref: EMBL:BC117246 xref: EMBL:CR749305 xref: HGNC:HGNC:16712 xref: UniGene:Hs.696040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005654 ! FBXW7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004629 name: FEZ1_human def: "Fasciculation and elongation protein zeta-1 gene" [UniProtKB:Q99689] xref: EMBL:BC009545 xref: EMBL:CR456817 xref: EMBL:CR541954 xref: EMBL:U60060 xref: EMBL:U60062 xref: EMBL:U69139 xref: HGNC:HGNC:3659 xref: UniGene:Hs.224008 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005393 ! FEZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004630 name: FEZ2_human def: "Fasciculation and elongation protein zeta-2 gene" [UniProtKB:Q9UHY8] xref: EMBL:AB076184 xref: EMBL:AC007401 xref: EMBL:AF113124 xref: EMBL:U60061 xref: EMBL:U69140 xref: HGNC:HGNC:3660 xref: UniGene:Hs.258563 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005394 ! FEZ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004631 name: FGF10_human def: "Fibroblast growth factor 10 precursor gene" [UniProtKB:O15520] xref: EMBL:AB002097 xref: EMBL:AF411527 xref: EMBL:AY604046 xref: EMBL:BC069561 xref: EMBL:BC105021 xref: EMBL:BC105023 xref: EMBL:CR541665 xref: EMBL:U67918 xref: HGNC:HGNC:3666 xref: UniGene:Hs.664499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001379 ! FGF10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004632 name: FGF1_human def: "Heparin-binding growth factor 1 precursor gene" [UniProtKB:P05230] synonym: "FGFA" EXACT [UniProtKB:P05230] xref: EMBL:AY601819 xref: EMBL:BC032697 xref: EMBL:M13361 xref: EMBL:M23086 xref: EMBL:M23087 xref: EMBL:M30490 xref: EMBL:M30491 xref: EMBL:M30492 xref: EMBL:M60515 xref: EMBL:M60516 xref: EMBL:S67291 xref: EMBL:X51943 xref: EMBL:X65778 xref: HGNC:HGNC:3665 xref: UniGene:Hs.483635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001486 ! FGF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004633 name: FGF2_human def: "Heparin-binding growth factor 2 precursor gene" [UniProtKB:P09038] synonym: "FGFB" EXACT [UniProtKB:P09038] xref: EMBL:J04513 xref: EMBL:M17599 xref: EMBL:M27968 xref: EMBL:X04431 xref: EMBL:X04432 xref: EMBL:X04433 xref: HGNC:HGNC:3676 xref: UniGene:Hs.284244 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001502 ! FGF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004634 name: FGF3_human def: "INT-2 proto-oncogene protein precursor gene" [UniProtKB:P11487] synonym: "INT2" EXACT [UniProtKB:P11487] xref: EMBL:BC113739 xref: EMBL:X14445 xref: HGNC:HGNC:3681 xref: UniGene:Hs.37092 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001511 ! FGF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004635 name: FGF4_human def: "Fibroblast growth factor 4 precursor gene" [UniProtKB:P08620] synonym: "HST" EXACT [UniProtKB:P08620] synonym: "HSTF1" EXACT [UniProtKB:P08620] synonym: "KS3" EXACT [UniProtKB:P08620] xref: EMBL:J02986 xref: EMBL:M17446 xref: HGNC:HGNC:3682 xref: UniGene:Hs.1755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001500 ! FGF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004636 name: FGF5_human def: "Fibroblast growth factor 5 precursor gene" [UniProtKB:P12034] xref: EMBL:AB016517 xref: EMBL:AF171928 xref: EMBL:DQ151636 xref: EMBL:M23534 xref: EMBL:M23535 xref: EMBL:M23536 xref: EMBL:M37825 xref: HGNC:HGNC:3683 xref: UniGene:Hs.37055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001514 ! FGF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004637 name: FGF6_human def: "Fibroblast growth factor 6 precursor gene" [UniProtKB:P10767] synonym: "HST2" EXACT [UniProtKB:P10767] xref: EMBL:AY581424 xref: EMBL:BC121097 xref: EMBL:BC121098 xref: EMBL:X14071 xref: EMBL:X14072 xref: EMBL:X14073 xref: EMBL:X57075 xref: EMBL:X63454 xref: HGNC:HGNC:3684 xref: UniGene:Hs.166015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001509 ! FGF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004638 name: FGF7_human def: "Keratinocyte growth factor precursor gene" [UniProtKB:P21781] synonym: "KGF" EXACT [UniProtKB:P21781] xref: EMBL:M60828 xref: EMBL:S81661 xref: HGNC:HGNC:3685 xref: UniGene:Hs.567268 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001545 ! FGF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004639 name: FGF8_human def: "Fibroblast growth factor 8 precursor gene" [UniProtKB:P55075] synonym: "AIGF" EXACT [UniProtKB:P55075] xref: EMBL:AB014615 xref: EMBL:AF520763 xref: EMBL:D38752 xref: EMBL:S78462 xref: EMBL:S78463 xref: EMBL:S78464 xref: EMBL:S78465 xref: EMBL:S78466 xref: EMBL:U36223 xref: EMBL:U36225 xref: EMBL:U36226 xref: EMBL:U36227 xref: EMBL:U36228 xref: EMBL:U46211 xref: EMBL:U46212 xref: EMBL:U46213 xref: EMBL:U47009 xref: EMBL:U47010 xref: EMBL:U47011 xref: EMBL:U56978 xref: HGNC:HGNC:3686 xref: UniGene:Hs.57710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001674 ! FGF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004640 name: FGF9_human def: "Glia-activating factor precursor gene" [UniProtKB:P31371] xref: EMBL:AL139378 xref: EMBL:AY682094 xref: EMBL:BC069692 xref: EMBL:BC103978 xref: EMBL:BC103979 xref: EMBL:D14838 xref: HGNC:HGNC:3687 xref: UniGene:Hs.111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001583 ! FGF9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004641 name: FGFBP1_human def: "Fibroblast growth factor-binding protein 1 precursor gene" [UniProtKB:Q14512] synonym: "FGFBP" EXACT [UniProtKB:Q14512] synonym: "HBP17" EXACT [UniProtKB:Q14512] xref: EMBL:AF149412 xref: EMBL:BC003628 xref: EMBL:BC008910 xref: EMBL:M60047 xref: HGNC:HGNC:19695 xref: UniGene:Hs.1690 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005646 ! FGFP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004642 name: FGFR1_human def: "Basic fibroblast growth factor receptor 1 precursor gene" [UniProtKB:P11362] synonym: "FGFBR" EXACT [UniProtKB:P11362] synonym: "FLG" EXACT [UniProtKB:P11362] synonym: "FLT2" EXACT [UniProtKB:P11362] xref: EMBL:A29216 xref: EMBL:AY585209 xref: EMBL:BC015035 xref: EMBL:BC018128 xref: EMBL:M34185 xref: EMBL:M34186 xref: EMBL:M34187 xref: EMBL:M34188 xref: EMBL:M34641 xref: EMBL:M37722 xref: EMBL:M60485 xref: EMBL:M63887 xref: EMBL:M63888 xref: EMBL:M63889 xref: EMBL:X51803 xref: EMBL:X52833 xref: EMBL:X57118 xref: EMBL:X57119 xref: EMBL:X57120 xref: EMBL:X57121 xref: EMBL:X57122 xref: EMBL:X66945 xref: EMBL:Y00665 xref: HGNC:HGNC:3688 xref: UniGene:Hs.264887 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005868 ! FGFR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004643 name: FGFR2_human def: "Fibroblast growth factor receptor 2 precursor gene" [UniProtKB:P21802] synonym: "BEK" EXACT [UniProtKB:P21802] synonym: "KGFR" EXACT [UniProtKB:P21802] synonym: "KSAM" EXACT [UniProtKB:P21802] xref: EMBL:AB030073 xref: EMBL:AB030074 xref: EMBL:AB030075 xref: EMBL:AB030076 xref: EMBL:AB030077 xref: EMBL:AB030078 xref: EMBL:AF097337 xref: EMBL:AF097338 xref: EMBL:AF097339 xref: EMBL:AF097340 xref: EMBL:AF097341 xref: EMBL:AF097342 xref: EMBL:AF097343 xref: EMBL:AF097344 xref: EMBL:AF097345 xref: EMBL:AF097346 xref: EMBL:AF097347 xref: EMBL:AF097348 xref: EMBL:AF097349 xref: EMBL:AF097350 xref: EMBL:AF097351 xref: EMBL:AF097352 xref: EMBL:AF097353 xref: EMBL:AF097354 xref: EMBL:AF169399 xref: EMBL:AF360695 xref: EMBL:AF410480 xref: EMBL:AF487553 xref: EMBL:BC039243 xref: EMBL:L49237 xref: EMBL:L49238 xref: EMBL:L49239 xref: EMBL:L49240 xref: EMBL:L49241 xref: EMBL:L49242 xref: EMBL:M35718 xref: EMBL:M55614 xref: EMBL:M80634 xref: EMBL:M87770 xref: EMBL:M87771 xref: EMBL:M87772 xref: EMBL:M97193 xref: EMBL:S82438 xref: EMBL:U11814 xref: EMBL:X52832 xref: EMBL:X56191 xref: EMBL:Y17131 xref: EMBL:Z71929 xref: HGNC:HGNC:3689 xref: UniGene:Hs.533683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005381 ! FGFR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004644 name: FGFR3_human def: "Fibroblast growth factor receptor 3 precursor gene" [UniProtKB:P22607] synonym: "JTK4" EXACT [UniProtKB:P22607] xref: EMBL:AF245114 xref: EMBL:AY768549 xref: EMBL:M58051 xref: EMBL:M59374 xref: EMBL:M64347 xref: EMBL:S76733 xref: EMBL:U22410 xref: EMBL:X84939 xref: HGNC:HGNC:3690 xref: UniGene:Hs.1420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005920 ! FGFR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004645 name: FHIT_human def: "Bis(5'-adenosyl)-triphosphatase gene" [UniProtKB:P49789] xref: EMBL:AY625256 xref: EMBL:BC032336 xref: EMBL:U46922 xref: EMBL:U76267 xref: EMBL:U76268 xref: EMBL:U76269 xref: EMBL:U76270 xref: EMBL:U76271 xref: HGNC:HGNC:3701 xref: UniGene:Hs.655995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001636 ! FHIT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004646 name: FHL2_human def: "Four and a half LIM domains protein 2 gene" [UniProtKB:Q14192] synonym: "DRAL" EXACT [UniProtKB:Q14192] synonym: "SLIM3" EXACT [UniProtKB:Q14192] xref: EMBL:AB038794 xref: EMBL:BC014397 xref: EMBL:L42176 xref: EMBL:U29332 xref: EMBL:U60117 xref: HGNC:HGNC:3703 xref: UniGene:Hs.443687 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005830 ! FHL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004647 name: FKBP1A_human def: "Peptidyl-prolyl cis-trans isomerase FKBP1A gene" [UniProtKB:P62942] synonym: "FKBP1" EXACT [UniProtKB:P62942] synonym: "FKBP12" EXACT [UniProtKB:P62942] xref: EMBL:AL109658 xref: EMBL:AL136531 xref: EMBL:BC001925 xref: EMBL:BC005147 xref: EMBL:BT007066 xref: EMBL:CR407613 xref: EMBL:CR542168 xref: EMBL:M34539 xref: EMBL:M80199 xref: EMBL:M92422 xref: EMBL:M92423 xref: EMBL:M93060 xref: EMBL:X52220 xref: EMBL:X55741 xref: HGNC:HGNC:3711 xref: UniGene:Hs.471933 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005655 ! FKB1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004648 name: FKBP6_human def: "FK506-binding protein 6 gene" [UniProtKB:O75344] synonym: "FKBP36" EXACT [UniProtKB:O75344] xref: EMBL:AF038847 xref: EMBL:BC036817 xref: HGNC:HGNC:3722 xref: UniGene:Hs.661266 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005219 ! FKBP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004649 name: WTAP_human def: "Pre-mRNA-splicing regulator WTAP gene" [UniProtKB:Q15007] synonym: "KIAA0105" EXACT [UniProtKB:Q15007] xref: EMBL:AF374416 xref: EMBL:AJ276706 xref: EMBL:AL135914 xref: EMBL:AL583911 xref: EMBL:BC000383 xref: EMBL:BC004432 xref: EMBL:BC069192 xref: EMBL:CH471051 xref: EMBL:D14661 xref: HGNC:HGNC:16846 xref: UniGene:Hs.446091 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001798 ! FL2D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004650 name: FLCN_human def: "Folliculin gene" [UniProtKB:Q8NFG4] synonym: "BHD" EXACT [UniProtKB:Q8NFG4] xref: EMBL:AC055811 xref: EMBL:AF517523 xref: EMBL:AK126951 xref: EMBL:AK127912 xref: EMBL:BC015687 xref: EMBL:BC015725 xref: EMBL:CH471196 xref: HGNC:HGNC:27310 xref: UniGene:Hs.513975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001981 ! FLCN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004651 name: FNBP1_human def: "Formin-binding protein 1 gene" [UniProtKB:Q96RU3] synonym: "FBP17" EXACT [UniProtKB:Q96RU3] synonym: "KIAA0554" EXACT [UniProtKB:Q96RU3] xref: EMBL:AB011126 xref: EMBL:AF265550 xref: EMBL:AK000975 xref: EMBL:AK023681 xref: EMBL:AL136141 xref: EMBL:AL158207 xref: EMBL:BC062463 xref: EMBL:BC101755 xref: HGNC:HGNC:17069 xref: UniGene:Hs.189409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005386 ! FNBP1_HUMAN relationship: codes_for CCO:B0054004 ! A8MS86_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004652 name: FOSB_human def: "Protein fosB gene" [UniProtKB:P53539] synonym: "G0S3" EXACT [UniProtKB:P53539] xref: EMBL:AY898963 xref: EMBL:BC036724 xref: EMBL:EU178110 xref: EMBL:EU178114 xref: EMBL:L49169 xref: HGNC:HGNC:3797 xref: UniGene:Hs.590958 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001664 ! FOSB_HUMAN relationship: codes_for CCO:B0054145 ! A8VJE6_HUMAN relationship: codes_for CCO:B0054146 ! A8VJG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004653 name: FOSL1_human def: "Fos-related antigen 1 gene" [UniProtKB:P15407] synonym: "FRA1" EXACT [UniProtKB:P15407] xref: EMBL:AJ297411 xref: EMBL:AJ297412 xref: EMBL:AJ297413 xref: EMBL:BC016648 xref: EMBL:X16707 xref: HGNC:HGNC:13718 xref: UniGene:Hs.283565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001522 ! FOSL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004654 name: FOXC1_human def: "Forkhead box protein C1 gene" [UniProtKB:Q12948] synonym: "FKHL7" EXACT [UniProtKB:Q12948] synonym: "FREAC3" EXACT [UniProtKB:Q12948] xref: EMBL:AF048693 xref: EMBL:AF078096 xref: EMBL:AL034344 xref: EMBL:AY228704 xref: EMBL:L12143 xref: EMBL:U13221 xref: HGNC:HGNC:3800 xref: UniGene:Hs.348883 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001735 ! FOXC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004655 name: FOXN3_human def: "Forkhead box protein N3 gene" [UniProtKB:O00409] synonym: "C14orf116" EXACT [UniProtKB:O00409] synonym: "CHES1" EXACT [UniProtKB:O00409] xref: EMBL:AC007263 xref: EMBL:AL138478 xref: EMBL:AL356805 xref: EMBL:AL357093 xref: EMBL:BC007506 xref: EMBL:U68723 xref: HGNC:HGNC:1928 xref: UniGene:Hs.434286 xref: UniGene:Hs.621371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001347 ! FOXN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004656 name: FOXO4_human def: "Forkhead box protein O4 gene" [UniProtKB:P98177] synonym: "AFX" EXACT [UniProtKB:P98177] synonym: "AFX1" EXACT [UniProtKB:P98177] synonym: "MLLT7" EXACT [UniProtKB:P98177] xref: EMBL:AF384029 xref: EMBL:BC106761 xref: EMBL:U10072 xref: EMBL:X93996 xref: EMBL:Y11284 xref: EMBL:Y11285 xref: EMBL:Y11286 xref: HGNC:HGNC:7139 xref: UniGene:Hs.584654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001706 ! FOXO4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004657 name: FRAP1_human def: "FKBP12-rapamycin complex-associated protein gene" [UniProtKB:P42345] synonym: "FRAP" EXACT [UniProtKB:P42345] synonym: "FRAP2" EXACT [UniProtKB:P42345] xref: EMBL:AJ300188 xref: EMBL:AL049653 xref: EMBL:AL109811 xref: EMBL:AL391561 xref: EMBL:BC117166 xref: EMBL:L34075 xref: EMBL:L35478 xref: EMBL:U88966 xref: HGNC:HGNC:3942 xref: UniGene:Hs.338207 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001611 ! FRAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004658 name: FTL_human def: "Ferritin light chain gene" [UniProtKB:P02792] xref: EMBL:BC002991 xref: EMBL:BC004245 xref: EMBL:BC008439 xref: EMBL:BC016346 xref: EMBL:BC016354 xref: EMBL:BC018990 xref: EMBL:BC058820 xref: EMBL:BC062708 xref: EMBL:BX571748 xref: EMBL:M10119 xref: EMBL:M11147 xref: EMBL:M12938 xref: EMBL:X03742 xref: EMBL:X03743 xref: HGNC:HGNC:3999 xref: UniGene:Hs.433670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006192 ! FRIL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004659 name: FRK_human def: "Tyrosine-protein kinase FRK gene" [UniProtKB:P42685] synonym: "PTK5" EXACT [UniProtKB:P42685] synonym: "RAK" EXACT [UniProtKB:P42685] xref: EMBL:AL121963 xref: EMBL:AL357141 xref: EMBL:BC012916 xref: EMBL:CH471051 xref: EMBL:U00803 xref: EMBL:U22322 xref: HGNC:HGNC:3955 xref: UniGene:Hs.89426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001613 ! FRK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004660 name: FRMD6_human def: "FERM domain-containing protein 6 gene" [UniProtKB:Q96NE9] synonym: "C14orf31" EXACT [UniProtKB:Q96NE9] xref: EMBL:AK055545 xref: EMBL:AL079307 xref: EMBL:BC020521 xref: EMBL:BC029870 xref: EMBL:BX161430 xref: EMBL:BX647863 xref: HGNC:HGNC:19839 xref: UniGene:Hs.434914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005267 ! FRMD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004661 name: FSHR_human def: "Follicle-stimulating hormone receptor precursor gene" [UniProtKB:P23945] synonym: "LGR1" EXACT [UniProtKB:P23945] xref: EMBL:AC092533 xref: EMBL:AY429104 xref: EMBL:BC096831 xref: EMBL:BC118548 xref: EMBL:BC125270 xref: EMBL:M65085 xref: EMBL:M95489 xref: EMBL:S59900 xref: EMBL:S73199 xref: EMBL:S73526 xref: EMBL:X68044 xref: HGNC:HGNC:3969 xref: UniGene:Hs.1428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005506 ! FSHR_HUMAN relationship: codes_for CCO:B0055747 ! Q05AH0_HUMAN relationship: codes_for CCO:B0056337 ! Q4ZFZ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004663 name: FH_human def: "Fumarate hydratase, mitochondrial precursor gene" [UniProtKB:P07954] xref: EMBL:BC003108 xref: EMBL:BC017444 xref: EMBL:BT009839 xref: EMBL:M15502 xref: EMBL:U48857 xref: EMBL:U59309 xref: HGNC:HGNC:3700 xref: UniGene:Hs.592490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001496 ! FUMH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004664 name: FXR1_human def: "Fragile X mental retardation syndrome-related protein 1 gene" [UniProtKB:P51114] xref: EMBL:AK292633 xref: EMBL:AY341428 xref: EMBL:BC028983 xref: EMBL:U25165 xref: HGNC:HGNC:4023 xref: UniGene:Hs.478407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006140 ! FXR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004665 name: FXYD6_human def: "FXYD domain-containing ion transport regulator 6 precursor gene" [UniProtKB:Q9H0Q3] synonym: "UNQ521/PRO1056" EXACT [UniProtKB:Q9H0Q3] xref: EMBL:AL136699 xref: EMBL:AL832811 xref: EMBL:AY358976 xref: EMBL:BC018652 xref: EMBL:BC093040 xref: EMBL:BT006717 xref: EMBL:CR533457 xref: HGNC:HGNC:4030 xref: UniGene:Hs.635508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006141 ! FXYD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004666 name: FYN_human def: "Proto-oncogene tyrosine-protein kinase Fyn gene" [UniProtKB:P06241] xref: EMBL:BC032496 xref: EMBL:M14333 xref: EMBL:M14676 xref: EMBL:S74774 xref: EMBL:Z97989 xref: HGNC:HGNC:4037 xref: UniGene:Hs.390567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005609 ! FYN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004667 name: FZR1_human def: "Fizzy-related protein homolog gene" [UniProtKB:Q9UM11] synonym: "CDH1" EXACT [UniProtKB:Q9UM11] synonym: "FYR" EXACT [UniProtKB:Q9UM11] synonym: "FZR" EXACT [UniProtKB:Q9UM11] synonym: "KIAA1242" EXACT [UniProtKB:Q9UM11] xref: EMBL:AB013462 xref: EMBL:AB013463 xref: EMBL:AB033068 xref: EMBL:AC005786 xref: EMBL:AC005787 xref: EMBL:AF080397 xref: EMBL:AF083810 xref: EMBL:AF102507 xref: EMBL:AF102508 xref: EMBL:AF433157 xref: EMBL:BC013413 xref: EMBL:BT007115 xref: HGNC:HGNC:24824 xref: UniGene:Hs.413133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002229 ! FZR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004668 name: G0S2_human def: "Putative lymphocyte G0/G1 switch protein 2 gene" [UniProtKB:P27469] xref: EMBL:AL031316 xref: EMBL:BC009694 xref: EMBL:M69199 xref: EMBL:M72885 xref: HGNC:HGNC:30229 xref: UniGene:Hs.432132 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001561 ! G0S2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004669 name: GAPDH_human def: "Glyceraldehyde-3-phosphate dehydrogenase gene" [UniProtKB:P04406] synonym: "CDABP0047" EXACT [UniProtKB:P04406] synonym: "GAPD" EXACT [UniProtKB:P04406] synonym: "OK/SW-cl.12" EXACT [UniProtKB:P04406] xref: EMBL:AB062273 xref: EMBL:AF261085 xref: EMBL:AY007133 xref: EMBL:AY340484 xref: EMBL:BC001601 xref: EMBL:BC004109 xref: EMBL:BC009081 xref: EMBL:BC013310 xref: EMBL:BC023632 xref: EMBL:BC025925 xref: EMBL:BC026907 xref: EMBL:BC029618 xref: EMBL:BC083511 xref: EMBL:BT006893 xref: EMBL:J02642 xref: EMBL:J04038 xref: EMBL:M17851 xref: EMBL:M33197 xref: EMBL:X01677 xref: EMBL:X53778 xref: HGNC:HGNC:4141 xref: UniGene:Hs.479728 xref: UniGene:Hs.544577 xref: UniGene:Hs.592355 xref: UniGene:Hs.648900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005458 ! G3P_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004670 name: GADD45GIP1_human def: "Growth arrest and DNA-damage-inducible proteins-interacting protein 1 gene" [UniProtKB:Q8TAE8] synonym: "PLINP1" EXACT [UniProtKB:Q8TAE8] synonym: "PRG6" EXACT [UniProtKB:Q8TAE8] xref: EMBL:AF147080 xref: EMBL:AF475095 xref: EMBL:AF479749 xref: EMBL:AJ295986 xref: EMBL:AJ429498 xref: EMBL:BC004944 xref: EMBL:BC013027 xref: EMBL:BC013039 xref: EMBL:BC069200 xref: HGNC:HGNC:29996 xref: UniGene:Hs.515164 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001987 ! G45IP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004671 name: GAS2L1_human def: "GAS2-like protein 1 gene" [UniProtKB:Q99501] synonym: "GAR22" EXACT [UniProtKB:Q99501] xref: EMBL:AK223602 xref: EMBL:BC001782 xref: EMBL:BC007624 xref: EMBL:BC011047 xref: EMBL:Y07846 xref: EMBL:Y07848 xref: HGNC:HGNC:16955 xref: UniGene:Hs.322852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002067 ! GA2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004672 name: GAS2L2_human def: "GAS2-like protein 2 gene" [UniProtKB:Q8NHY3] synonym: "GAR17" EXACT [UniProtKB:Q8NHY3] xref: EMBL:AF508784 xref: EMBL:AF508785 xref: HGNC:HGNC:24846 xref: UniGene:Hs.591194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001985 ! GA2L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004673 name: GAS2L3_human def: "GAS2-like protein 3 gene" [UniProtKB:Q86XJ1] xref: EMBL:BC043366 xref: HGNC:HGNC:27475 xref: UniGene:Hs.20575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001944 ! GA2L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004674 name: GADD45A_human def: "Growth arrest and DNA-damage-inducible protein GADD45 alpha gene" [UniProtKB:P24522] synonym: "DDIT1" EXACT [UniProtKB:P24522] synonym: "GADD45" EXACT [UniProtKB:P24522] xref: EMBL:AY135686 xref: EMBL:BC011757 xref: EMBL:L24498 xref: EMBL:M60974 xref: HGNC:HGNC:4095 xref: UniGene:Hs.80409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001552 ! GA45A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004675 name: GADD45B_human def: "Growth arrest and DNA-damage-inducible protein GADD45 beta gene" [UniProtKB:O75293] synonym: "MYD118" EXACT [UniProtKB:O75293] xref: EMBL:AC005624 xref: EMBL:AF078077 xref: EMBL:AF087853 xref: EMBL:AF090950 xref: EMBL:AF533019 xref: EMBL:BC113466 xref: EMBL:BC117469 xref: HGNC:HGNC:4096 xref: UniGene:Hs.110571 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001424 ! GA45B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004676 name: GADD45G_human def: "Growth arrest and DNA-damage-inducible protein GADD45 gamma gene" [UniProtKB:O95257] synonym: "CR6" EXACT [UniProtKB:O95257] synonym: "DDIT2" EXACT [UniProtKB:O95257] xref: EMBL:AF078078 xref: EMBL:AF079806 xref: EMBL:AF087883 xref: EMBL:AF265659 xref: EMBL:AF494037 xref: EMBL:BC000465 xref: EMBL:BC019325 xref: EMBL:BT007234 xref: HGNC:HGNC:4097 xref: UniGene:Hs.9701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005411 ! GA45G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004677 name: GAB2_human def: "GRB2-associated-binding protein 2 gene" [UniProtKB:Q9UQC2] synonym: "KIAA0571" EXACT [UniProtKB:Q9UQC2] xref: EMBL:AB011143 xref: EMBL:AB018413 xref: HGNC:HGNC:14458 xref: UniGene:Hs.429434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005924 ! GAB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004678 name: GABPB2_human def: "GA-binding protein subunit beta-2 gene" [UniProtKB:Q8TAK5] xref: EMBL:AK092230 xref: EMBL:AL590133 xref: EMBL:AL592424 xref: EMBL:AL691467 xref: EMBL:BC027033 xref: EMBL:CH471121 xref: HGNC:HGNC:28441 xref: UniGene:Hs.654699 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005209 ! GABP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004679 name: GABPA_human def: "GA-binding protein alpha chain gene" [UniProtKB:Q06546] synonym: "E4TF1A" EXACT [UniProtKB:Q06546] xref: EMBL:D13318 xref: EMBL:U13044 xref: HGNC:HGNC:4071 xref: UniGene:Hs.246310 xref: UniGene:Hs.473470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005878 ! GABPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004680 name: GABBR1_human def: "Gamma-aminobutyric acid type B receptor subunit 1 precursor gene" [UniProtKB:Q9UBS5] synonym: "GPRC3A" EXACT [UniProtKB:Q9UBS5] xref: EMBL:AF099148 xref: EMBL:AJ010170 xref: EMBL:AJ010171 xref: EMBL:AJ010172 xref: EMBL:AJ010173 xref: EMBL:AJ010174 xref: EMBL:AJ010175 xref: EMBL:AJ010176 xref: EMBL:AJ010177 xref: EMBL:AJ010178 xref: EMBL:AJ010179 xref: EMBL:AJ010180 xref: EMBL:AJ010181 xref: EMBL:AJ010182 xref: EMBL:AJ010183 xref: EMBL:AJ010184 xref: EMBL:AJ010185 xref: EMBL:AJ010186 xref: EMBL:AJ010187 xref: EMBL:AJ010188 xref: EMBL:AJ010189 xref: EMBL:AJ010190 xref: EMBL:AJ010191 xref: EMBL:AJ012185 xref: EMBL:AJ012186 xref: EMBL:AJ012187 xref: EMBL:AJ012288 xref: EMBL:AJ225028 xref: EMBL:AJ225029 xref: EMBL:AL031983 xref: EMBL:AL645936 xref: EMBL:BC042598 xref: EMBL:BC050532 xref: EMBL:CR388210 xref: EMBL:Y11044 xref: HGNC:HGNC:4070 xref: UniGene:Hs.167017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006317 ! GABR1_HUMAN relationship: codes_for CCO:B0041921 ! B0UXY8_HUMAN relationship: codes_for CCO:B0041925 ! B0UXY7_HUMAN relationship: codes_for CCO:B0041927 ! A6NNW8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004681 name: GAK_human def: "Cyclin G-associated kinase gene" [UniProtKB:O14976] xref: EMBL:BC000816 xref: EMBL:BC008668 xref: EMBL:D88435 xref: HGNC:HGNC:4113 xref: UniGene:Hs.369607 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001364 ! GAK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004682 name: GAS1_human def: "Growth arrest-specific protein 1 precursor gene" [UniProtKB:P54826] xref: EMBL:L13698 xref: HGNC:HGNC:4165 xref: UniGene:Hs.65029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001672 ! GAS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004683 name: GAS2_human def: "Growth arrest-specific protein 2 gene" [UniProtKB:O43903] xref: EMBL:BC040470 xref: EMBL:CR450285 xref: EMBL:U95032 xref: HGNC:HGNC:4167 xref: UniGene:Hs.702150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001401 ! GAS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004684 name: GAS7_human def: "Growth arrest-specific protein 7 gene" [UniProtKB:O60861] synonym: "KIAA0394" EXACT [UniProtKB:O60861] xref: EMBL:AB007854 xref: EMBL:AF231998 xref: EMBL:AJ224876 xref: EMBL:BC001152 xref: EMBL:BC006454 xref: HGNC:HGNC:4169 xref: UniGene:Hs.258855 xref: UniGene:Hs.462214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001417 ! GAS7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004685 name: GPRASP2_human def: "G-protein coupled receptor-associated sorting protein 2 gene" [UniProtKB:Q96D09] xref: EMBL:AK092981 xref: EMBL:AL035427 xref: EMBL:BC013576 xref: EMBL:BC036772 xref: HGNC:HGNC:25169 xref: UniGene:Hs.656888 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005405 ! GASP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004686 name: GNB5_human def: "Guanine nucleotide-binding protein subunit beta-5 gene" [UniProtKB:O14775] xref: EMBL:AF017656 xref: EMBL:AF300650 xref: EMBL:AF501885 xref: EMBL:BC013997 xref: HGNC:HGNC:4401 xref: UniGene:Hs.155090 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006142 ! GBB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004687 name: GBF1_human def: "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 gene" [UniProtKB:Q92538] synonym: "KIAA0248" EXACT [UniProtKB:Q92538] xref: EMBL:AF068755 xref: EMBL:AL121928 xref: EMBL:AL160011 xref: EMBL:AL356420 xref: EMBL:BC007941 xref: EMBL:BC014171 xref: EMBL:D87435 xref: HGNC:HGNC:4181 xref: UniGene:Hs.290243 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005359 ! GBF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004688 name: GNB2L1_human def: "Guanine nucleotide-binding protein subunit beta-2-like 1 gene" [UniProtKB:P63244] xref: EMBL:BC000214 xref: EMBL:BC000366 xref: EMBL:BC010119 xref: EMBL:BC014256 xref: EMBL:BC014788 xref: EMBL:BC017287 xref: EMBL:BC019093 xref: EMBL:BC019362 xref: EMBL:BC021993 xref: EMBL:BC032006 xref: EMBL:CR456978 xref: EMBL:M24194 xref: HGNC:HGNC:4399 xref: UniGene:Hs.5662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005739 ! GBLP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004689 name: GABARAP_human def: "Gamma-aminobutyric acid receptor-associated protein gene" [UniProtKB:O95166] synonym: "FLC3B" EXACT [UniProtKB:O95166] synonym: "HT004" EXACT [UniProtKB:O95166] xref: EMBL:AB030711 xref: EMBL:AF044671 xref: EMBL:AF067171 xref: EMBL:AF161586 xref: EMBL:AF183425 xref: HGNC:HGNC:4067 xref: UniGene:Hs.647421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006196 ! GBRAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004690 name: GCN5L2_human def: "General control of amino acid synthesis protein 5-like 2 gene" [UniProtKB:Q92830] synonym: "GCN5" EXACT [UniProtKB:Q92830] synonym: "HGCN5" EXACT [UniProtKB:Q92830] xref: EMBL:AF029777 xref: EMBL:BC032743 xref: EMBL:BC039907 xref: EMBL:BC105977 xref: EMBL:CH471152 xref: EMBL:U57316 xref: HGNC:HGNC:4201 xref: UniGene:Hs.463045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005647 ! GCNL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004691 name: GDF9_human def: "Growth/differentiation factor 9 precursor gene" [UniProtKB:O60383] xref: EMBL:AC004500 xref: EMBL:BC096228 xref: EMBL:BC096229 xref: EMBL:BC096230 xref: EMBL:BC096231 xref: HGNC:HGNC:4224 xref: UniGene:Hs.25022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006180 ! GDF9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004692 name: ARHGDIA_human def: "Rho GDP-dissociation inhibitor 1 gene" [UniProtKB:P52565] synonym: "GDIA1" EXACT [UniProtKB:P52565] xref: EMBL:AF498926 xref: EMBL:BC005851 xref: EMBL:BC005875 xref: EMBL:BC008701 xref: EMBL:BC009759 xref: EMBL:BC016031 xref: EMBL:BC016185 xref: EMBL:BC024258 xref: EMBL:BC027730 xref: EMBL:BC075827 xref: EMBL:BC106044 xref: EMBL:BT006884 xref: EMBL:CH471099 xref: EMBL:CR456777 xref: EMBL:D13989 xref: EMBL:M97579 xref: EMBL:X63863 xref: EMBL:X69550 xref: HGNC:HGNC:678 xref: UniGene:Hs.159161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032833 ! GDIR1_HUMAN relationship: codes_for CCO:B0063439 ! Q6IBM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004693 name: GMNN_human def: "Geminin gene" [UniProtKB:O75496] xref: EMBL:AF067855 xref: EMBL:AL133264 xref: EMBL:BC005185 xref: EMBL:BC005389 xref: HGNC:HGNC:17493 xref: UniGene:Hs.234896 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001432 ! GEMI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004694 name: GFI1B_human def: "Zinc finger protein Gfi-1b gene" [UniProtKB:Q5VTD9] xref: EMBL:AF081946 xref: EMBL:AL593851 xref: EMBL:AY428733 xref: EMBL:BC035626 xref: EMBL:BC043371 xref: EMBL:CH471090 xref: EMBL:CR536546 xref: HGNC:HGNC:4238 xref: UniGene:Hs.553160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001898 ! GFI1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004695 name: GFI1_human def: "Zinc finger protein Gfi-1 gene" [UniProtKB:Q99684] synonym: "ZNF163" EXACT [UniProtKB:Q99684] xref: EMBL:BC032751 xref: EMBL:BC074866 xref: EMBL:BC074867 xref: EMBL:U67369 xref: HGNC:HGNC:4237 xref: UniGene:Hs.73172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002083 ! GFI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004696 name: GGA1_human def: "ADP-ribosylation factor-binding protein GGA1 gene" [UniProtKB:Q9UJY5] xref: EMBL:AF190862 xref: EMBL:AF218584 xref: EMBL:AF233521 xref: EMBL:AK075256 xref: EMBL:AL035496 xref: EMBL:AL110219 xref: EMBL:BC000538 xref: EMBL:Z83844 xref: HGNC:HGNC:17842 xref: UniGene:Hs.499158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005670 ! GGA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004697 name: GGA2_human def: "ADP-ribosylation factor-binding protein GGA2 gene" [UniProtKB:Q9UJY4] synonym: "KIAA1080" EXACT [UniProtKB:Q9UJY4] xref: EMBL:AB029003 xref: EMBL:AC002400 xref: EMBL:AF165531 xref: EMBL:AF190863 xref: EMBL:AF233522 xref: EMBL:AF323754 xref: EMBL:BC000284 xref: HGNC:HGNC:16064 xref: UniGene:Hs.460336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005200 ! GGA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004698 name: GGA3_human def: "ADP-ribosylation factor-binding protein GGA3 gene" [UniProtKB:Q9NZ52] synonym: "KIAA0154" EXACT [UniProtKB:Q9NZ52] xref: EMBL:AF190864 xref: EMBL:AF219138 xref: EMBL:AF219139 xref: EMBL:BC070044 xref: EMBL:D63876 xref: HGNC:HGNC:17079 xref: UniGene:Hs.87726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005930 ! GGA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004699 name: GIT1_human def: "ARF GTPase-activating protein GIT1 gene" [UniProtKB:Q9Y2X7] xref: EMBL:AF124490 xref: EMBL:BC006227 xref: EMBL:BC048196 xref: HGNC:HGNC:4272 xref: UniGene:Hs.514051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005397 ! GIT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004700 name: GKN1_human def: "Gastrokine-1 precursor gene" [UniProtKB:Q9NS71] synonym: "AMP18" EXACT [UniProtKB:Q9NS71] synonym: "CA11" EXACT [UniProtKB:Q9NS71] synonym: "UNQ489/PRO1005" EXACT [UniProtKB:Q9NS71] xref: EMBL:AB039886 xref: EMBL:AY139182 xref: EMBL:AY139184 xref: EMBL:AY359050 xref: EMBL:BC059778 xref: HGNC:HGNC:23217 xref: UniGene:Hs.69319 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002164 ! GKN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004701 name: CGA_human def: "Glycoprotein hormones alpha chain precursor gene" [UniProtKB:P01215] xref: EMBL:BC020782 xref: EMBL:BC055080 xref: EMBL:J00150 xref: EMBL:J00151 xref: EMBL:J00152 xref: EMBL:S70583 xref: EMBL:S70584 xref: EMBL:S70585 xref: EMBL:V00518 xref: HGNC:HGNC:1885 xref: UniGene:Hs.119689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006263 ! GLHA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004702 name: GLI3_human def: "Zinc finger protein GLI3 gene" [UniProtKB:P10071] xref: EMBL:AC005026 xref: EMBL:AC005028 xref: EMBL:AC005158 xref: EMBL:AJ250408 xref: EMBL:BC113616 xref: EMBL:BC117168 xref: EMBL:CH236951 xref: EMBL:M20674 xref: EMBL:M57609 xref: HGNC:HGNC:4319 xref: UniGene:Hs.21509 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005850 ! GLI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004703 name: GLIS3_human def: "Zinc finger protein GLIS3 gene" [UniProtKB:Q8NEA6] synonym: "ZNF515" EXACT [UniProtKB:Q8NEA6] xref: EMBL:AL133283 xref: EMBL:AL137071 xref: EMBL:AL158012 xref: EMBL:BC033899 xref: HGNC:HGNC:28510 xref: UniGene:Hs.162125 xref: UniGene:Hs.644570 xref: UniGene:Hs.648821 xref: UniGene:Hs.677552 xref: UniGene:Hs.699131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005201 ! GLIS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004704 name: PRKCSH_human def: "Glucosidase 2 subunit beta precursor gene" [UniProtKB:P14314] synonym: "G19P1" EXACT [UniProtKB:P14314] xref: EMBL:AF144075 xref: EMBL:BC013586 xref: EMBL:BC015154 xref: EMBL:BT009858 xref: EMBL:J03075 xref: EMBL:U50317 xref: EMBL:U50318 xref: EMBL:U50319 xref: EMBL:U50320 xref: EMBL:U50321 xref: EMBL:U50322 xref: EMBL:U50323 xref: EMBL:U50324 xref: EMBL:U50325 xref: EMBL:U50326 xref: HGNC:HGNC:9411 xref: UniGene:Hs.610830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006228 ! GLU2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004705 name: GLYAT_human def: "Glycine N-acyltransferase gene" [UniProtKB:Q6IB77] synonym: "ACGNAT" EXACT [UniProtKB:Q6IB77] synonym: "CAT" EXACT [UniProtKB:Q6IB77] synonym: "GAT" EXACT [UniProtKB:Q6IB77] xref: EMBL:AB013093 xref: EMBL:AF023466 xref: EMBL:BC009785 xref: EMBL:CR456927 xref: HGNC:HGNC:13734 xref: UniGene:Hs.145384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006195 ! GLYAT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004706 name: SHMT1_human def: "Serine hydroxymethyltransferase, cytosolic gene" [UniProtKB:P34896] xref: EMBL:BC022874 xref: EMBL:BC038598 xref: EMBL:L11931 xref: EMBL:L23928 xref: EMBL:Y14485 xref: EMBL:Y14486 xref: EMBL:Y14487 xref: HGNC:HGNC:10850 xref: UniGene:Hs.513987 xref: UniGene:Hs.636044 xref: UniGene:Hs.706506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006184 ! GLYC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004707 name: GML_human def: "Glycosyl-phosphatidylinositol-anchored molecule-like protein precursor gene" [UniProtKB:Q99445] synonym: "LY6DL" EXACT [UniProtKB:Q99445] xref: EMBL:AB000381 xref: EMBL:BC074930 xref: EMBL:BC126336 xref: EMBL:BC126338 xref: EMBL:D84290 xref: HGNC:HGNC:4375 xref: UniGene:Hs.661218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002064 ! GML_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004708 name: GNA13_human def: "Guanine nucleotide-binding protein subunit alpha-13 gene" [UniProtKB:Q14344] xref: EMBL:AF493902 xref: EMBL:BC036756 xref: EMBL:L22075 xref: HGNC:HGNC:4381 xref: UniGene:Hs.515018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005635 ! GNA13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004709 name: GNAI1_human def: "Guanine nucleotide-binding protein G(i), alpha-1 subunit gene" [UniProtKB:P63096] xref: EMBL:AF055013 xref: EMBL:AF493905 xref: EMBL:AL049933 xref: EMBL:BC026326 xref: EMBL:BT019775 xref: EMBL:M17219 xref: EMBL:M20594 xref: EMBL:M20595 xref: EMBL:M20596 xref: HGNC:HGNC:4384 xref: UniGene:Hs.134587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005493 ! GNAI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004710 name: GNAI2_human def: "Guanine nucleotide-binding protein G(i), alpha-2 subunit gene" [UniProtKB:P04899] synonym: "GNAI2B" EXACT [UniProtKB:P04899] xref: EMBL:AF493906 xref: EMBL:BC012138 xref: EMBL:BC016995 xref: EMBL:J03004 xref: EMBL:M20586 xref: EMBL:M20587 xref: EMBL:M20588 xref: EMBL:M20589 xref: EMBL:M20590 xref: EMBL:M20591 xref: EMBL:M20592 xref: EMBL:M20593 xref: EMBL:M69012 xref: EMBL:X04828 xref: EMBL:X07854 xref: HGNC:HGNC:4385 xref: UniGene:Hs.77269 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005754 ! GNAI2_HUMAN relationship: codes_for CCO:B0058406 ! Q99061_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004711 name: RALGDS_human def: "Ral guanine nucleotide dissociation stimulator gene" [UniProtKB:Q12967] synonym: "KIAA1308" EXACT [UniProtKB:Q12967] synonym: "RGF" EXACT [UniProtKB:Q12967] xref: EMBL:AB037729 xref: EMBL:AF027169 xref: EMBL:AF295773 xref: EMBL:AF295775 xref: EMBL:AF295778 xref: EMBL:AF295780 xref: EMBL:AL162417 xref: EMBL:BC059362 xref: EMBL:CH471090 xref: EMBL:U14417 xref: HGNC:HGNC:9842 xref: UniGene:Hs.106185 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005912 ! GNDS_HUMAN relationship: codes_for CCO:B0016356 ! Q6KH11_HUMAN relationship: codes_for CCO:B0016357 ! Q6PCE1_HUMAN relationship: codes_for CCO:B0016364 ! Q5T7U6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004712 name: GNL3_human def: "Guanine nucleotide-binding protein-like 3 gene" [UniProtKB:Q9BVP2] synonym: "E2IG3" EXACT [UniProtKB:Q9BVP2] synonym: "NS" EXACT [UniProtKB:Q9BVP2] xref: EMBL:AF191018 xref: EMBL:AK027514 xref: EMBL:AK027516 xref: EMBL:BC001024 xref: HGNC:HGNC:29931 xref: UniGene:Hs.313544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002103 ! GNL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004713 name: GNPTG_human def: "N-acetylglucosamine-1-phosphotransferase subunit gamma precursor gene" [UniProtKB:Q9UJJ9] synonym: "CAB56184" EXACT [UniProtKB:Q9UJJ9] synonym: "GNPTAG" EXACT [UniProtKB:Q9UJJ9] synonym: "LP2537" EXACT [UniProtKB:Q9UJJ9] xref: EMBL:AF302786 xref: EMBL:AL031709 xref: EMBL:AY203933 xref: EMBL:BC014592 xref: HGNC:HGNC:23026 xref: UniGene:Hs.241575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005572 ! GNPTG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004714 name: GOLGA2_human def: "Golgin subfamily A member 2 gene" [UniProtKB:Q08379] xref: EMBL:AF248953 xref: EMBL:AL590708 xref: EMBL:BC006381 xref: EMBL:BC014188 xref: EMBL:BC069268 xref: EMBL:BT007248 xref: EMBL:L06147 xref: HGNC:HGNC:4425 xref: UniGene:Hs.155827 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006274 ! GOGA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004715 name: GOLGB1_human def: "Golgin subfamily B member 1 gene" [UniProtKB:Q14789] xref: EMBL:D25542 xref: EMBL:X75304 xref: HGNC:HGNC:4429 xref: UniGene:Hs.213389 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006272 ! GOGB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004716 name: GOLM1_human def: "Golgi membrane protein 1 gene" [UniProtKB:Q8NBJ4] synonym: "C9orf155" EXACT [UniProtKB:Q8NBJ4] synonym: "GOLPH2" EXACT [UniProtKB:Q8NBJ4] synonym: "PSEC0242" EXACT [UniProtKB:Q8NBJ4] synonym: "UNQ686/PRO1326" EXACT [UniProtKB:Q8NBJ4] xref: EMBL:AF236056 xref: EMBL:AK075542 xref: EMBL:AY358593 xref: EMBL:BC001740 xref: EMBL:CR457201 xref: HGNC:HGNC:15451 xref: UniGene:Hs.696129 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006331 ! GOLM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004717 name: GORASP2_human def: "Golgi reassembly-stacking protein 2 gene" [UniProtKB:Q9H8Y8] xref: EMBL:AK023082 xref: EMBL:AK023201 xref: EMBL:AK027349 xref: EMBL:AL117430 xref: EMBL:BC007770 xref: HGNC:HGNC:17500 xref: UniGene:Hs.431317 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005241 ! GORS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004718 name: GPR132_human def: "Probable G-protein coupled receptor 132 gene" [UniProtKB:Q9UNW8] synonym: "G2A" EXACT [UniProtKB:Q9UNW8] xref: EMBL:AF083955 xref: EMBL:BC004555 xref: EMBL:BC084546 xref: EMBL:BT007257 xref: HGNC:HGNC:17482 xref: UniGene:Hs.532504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002236 ! GP132_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004719 name: GPR135_human def: "Probable G-protein coupled receptor 135 gene" [UniProtKB:Q8IZ08] xref: EMBL:AB065563 xref: EMBL:AY255588 xref: EMBL:AY288418 xref: EMBL:BC032831 xref: HGNC:HGNC:19991 xref: UniGene:Hs.647573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006306 ! GP135_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004720 name: GP1BA_human def: "Platelet glycoprotein Ib alpha chain precursor gene" [UniProtKB:P07359] xref: EMBL:AB038516 xref: EMBL:AB086948 xref: EMBL:AF395009 xref: EMBL:BC027955 xref: EMBL:D85894 xref: EMBL:J02940 xref: EMBL:L39103 xref: EMBL:M22403 xref: EMBL:S34436 xref: EMBL:S34439 xref: HGNC:HGNC:4439 xref: UniGene:Hs.1472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005631 ! GP1BA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004721 name: GPAA1_human def: "Glycosylphosphatidylinositol anchor attachment 1 protein gene" [UniProtKB:O43292] synonym: "GAA1" EXACT [UniProtKB:O43292] xref: EMBL:AB002135 xref: EMBL:AB002137 xref: EMBL:AB006969 xref: EMBL:AB017267 xref: EMBL:AL157437 xref: EMBL:BC003171 xref: EMBL:BC004129 xref: EMBL:BC006383 xref: HGNC:HGNC:4446 xref: UniGene:Hs.627962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006273 ! GPAA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004722 name: GPD1_human def: "Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic gene" [UniProtKB:P21695] xref: EMBL:BC032234 xref: EMBL:L34041 xref: EMBL:M36917 xref: HGNC:HGNC:4455 xref: UniGene:Hs.524418 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006143 ! GPDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004723 name: GPS2_human def: "G protein pathway suppressor 2 gene" [UniProtKB:Q13227] xref: EMBL:AL122080 xref: EMBL:AL157493 xref: EMBL:BC013652 xref: EMBL:U28963 xref: HGNC:HGNC:4550 xref: UniGene:Hs.438219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001746 ! GPS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004724 name: GPSM2_human def: "G-protein-signaling modulator 2 gene" [UniProtKB:P81274] synonym: "LGN" EXACT [UniProtKB:P81274] xref: EMBL:AL449266 xref: EMBL:AY136740 xref: EMBL:BC027732 xref: EMBL:CH471122 xref: EMBL:U54999 xref: HGNC:HGNC:29501 xref: UniGene:Hs.584901 xref: UniGene:Hs.658489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005492 ! GPSM2_HUMAN relationship: codes_for CCO:B0054182 ! B0QZD1_HUMAN relationship: codes_for CCO:B0056563 ! Q5T1N8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004725 name: GRB2_human def: "Growth factor receptor-bound protein 2 gene" [UniProtKB:P62993] synonym: "ASH" EXACT [UniProtKB:P62993] xref: EMBL:AF063614 xref: EMBL:AF063615 xref: EMBL:AF063616 xref: EMBL:AF063617 xref: EMBL:AF063618 xref: EMBL:AF498925 xref: EMBL:BC000631 xref: EMBL:CR541942 xref: EMBL:L29511 xref: EMBL:M96995 xref: EMBL:X62852 xref: HGNC:HGNC:4566 xref: UniGene:Hs.444356 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005454 ! GRB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004726 name: GRIK5_human def: "Glutamate receptor, ionotropic kainate 5 precursor gene" [UniProtKB:Q16478] synonym: "GRIK2" EXACT [UniProtKB:Q16478] xref: EMBL:AJ249209 xref: EMBL:CH471126 xref: EMBL:S40369 xref: HGNC:HGNC:4583 xref: UniGene:Hs.367799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006285 ! GRIK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004727 name: GPRIN2_human def: "G protein-regulated inducer of neurite outgrowth 2 gene" [UniProtKB:O60269] synonym: "KIAA0514" EXACT [UniProtKB:O60269] xref: EMBL:AB011086 xref: EMBL:AL645529 xref: EMBL:BC011672 xref: HGNC:HGNC:23730 xref: UniGene:Hs.523375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005311 ! GRIN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004728 name: GRIP2_human def: "Glutamate receptor-interacting protein 2 gene" [UniProtKB:Q9C0E4] synonym: "KIAA1719" EXACT [UniProtKB:Q9C0E4] xref: EMBL:AB051506 xref: EMBL:AK024507 xref: EMBL:AK074145 xref: HGNC:HGNC:23841 xref: UniGene:Hs.517819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005960 ! GRIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004729 name: GRLF1_human def: "Glucocorticoid receptor DNA-binding factor 1 gene" [UniProtKB:Q9NRY4] synonym: "GRF1" EXACT [UniProtKB:Q9NRY4] synonym: "KIAA1722" EXACT [UniProtKB:Q9NRY4] xref: EMBL:AB051509 xref: EMBL:AF159851 xref: EMBL:M73077 xref: HGNC:HGNC:4591 xref: UniGene:Hs.509447 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002160 ! GRLF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004730 name: GRN_human def: "Granulins precursor gene" [UniProtKB:P28799] xref: EMBL:AF055008 xref: EMBL:BC000324 xref: EMBL:BC010577 xref: EMBL:M75161 xref: EMBL:X62320 xref: HGNC:HGNC:4601 xref: UniGene:Hs.514220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005961 ! GRN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004731 name: HSPA9_human def: "Stress-70 protein, mitochondrial precursor gene" [UniProtKB:P38646] synonym: "GRP75" EXACT [UniProtKB:P38646] synonym: "HSPA9B" EXACT [UniProtKB:P38646] xref: EMBL:AK222758 xref: EMBL:AK315177 xref: EMBL:BC000478 xref: EMBL:BC024034 xref: EMBL:CH471062 xref: EMBL:DQ531046 xref: EMBL:L11066 xref: EMBL:L15189 xref: HGNC:HGNC:5244 xref: UniGene:Hs.184233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005828 ! GRP75_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004732 name: HSPA5_human def: "78 kDa glucose-regulated protein precursor gene" [UniProtKB:P11021] synonym: "GRP78" EXACT [UniProtKB:P11021] xref: EMBL:AF188611 xref: EMBL:AF216292 xref: EMBL:AJ271729 xref: EMBL:BC020235 xref: EMBL:DQ385847 xref: EMBL:M19645 xref: EMBL:X59969 xref: EMBL:X87949 xref: HGNC:HGNC:5238 xref: UniGene:Hs.605502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005843 ! GRP78_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004733 name: GRWD1_human def: "Glutamate-rich WD repeat-containing protein 1 gene" [UniProtKB:Q9BQ67] synonym: "GRWD" EXACT [UniProtKB:Q9BQ67] synonym: "KIAA1942" EXACT [UniProtKB:Q9BQ67] synonym: "WDR28" EXACT [UniProtKB:Q9BQ67] xref: EMBL:AB075822 xref: EMBL:AF337808 xref: EMBL:BC002440 xref: HGNC:HGNC:21270 xref: UniGene:Hs.400625 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005687 ! GRWD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004734 name: GSE1_human def: "Genetic suppressor element 1 gene" [UniProtKB:Q14687] synonym: "KIAA0182" EXACT [UniProtKB:Q14687] xref: EMBL:BC000753 xref: EMBL:BC009854 xref: EMBL:BC037556 xref: EMBL:BQ214916 xref: EMBL:D80004 xref: HGNC:HGNC:28979 xref: UniGene:Hs.461647 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005595 ! GSE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004735 name: GSPT1_human def: "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A gene" [UniProtKB:P15170] synonym: "ERF3A" EXACT [UniProtKB:P15170] xref: EMBL:U95742 xref: EMBL:X17644 xref: HGNC:HGNC:4621 xref: UniGene:Hs.528780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001520 ! ERF3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004736 name: GSTM4_human def: "Glutathione S-transferase Mu 4 gene" [UniProtKB:Q03013] xref: EMBL:BC015513 xref: EMBL:BC108729 xref: EMBL:CR541869 xref: EMBL:M96233 xref: EMBL:M96234 xref: EMBL:M99422 xref: EMBL:X56837 xref: EMBL:X68677 xref: HGNC:HGNC:4636 xref: UniGene:Hs.348387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006144 ! GSTM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004737 name: GSTP1_human def: "Glutathione S-transferase P gene" [UniProtKB:P09211] synonym: "FAEES3" EXACT [UniProtKB:P09211] synonym: "GST3" EXACT [UniProtKB:P09211] xref: EMBL:AY324387 xref: EMBL:BC010915 xref: EMBL:BT019949 xref: EMBL:BT019950 xref: EMBL:CR450361 xref: EMBL:M24485 xref: EMBL:U12472 xref: EMBL:U21689 xref: EMBL:U30897 xref: EMBL:U62589 xref: EMBL:X06547 xref: EMBL:X08058 xref: EMBL:X08094 xref: EMBL:X08095 xref: EMBL:X08096 xref: EMBL:X15480 xref: HGNC:HGNC:4638 xref: UniGene:Hs.523836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006145 ! GSTP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004738 name: SLC2A4_human def: "Solute carrier family 2, facilitated glucose transporter member 4 gene" [UniProtKB:P14672] synonym: "GLUT4" EXACT [UniProtKB:P14672] xref: EMBL:BC069615 xref: EMBL:BC069621 xref: EMBL:BC113592 xref: EMBL:BC126164 xref: EMBL:M20747 xref: EMBL:M91463 xref: EMBL:X58489 xref: HGNC:HGNC:11009 xref: UniGene:Hs.380691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005473 ! GTR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004739 name: GTSE1_human def: "G2 and S phase-expressed protein 1 gene" [UniProtKB:Q9NYZ3] xref: EMBL:AF223408 xref: EMBL:AK222806 xref: EMBL:AK315550 xref: EMBL:AL031588 xref: EMBL:BC006325 xref: EMBL:BC075828 xref: EMBL:CT841519 xref: EMBL:Z93024 xref: HGNC:HGNC:13698 xref: UniGene:Hs.386189 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002180 ! GTSE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004741 name: HIST1H1A_human def: "Histone H1.1 gene" [UniProtKB:Q02539] synonym: "H1F1" EXACT [UniProtKB:Q02539] xref: EMBL:AF531299 xref: EMBL:BC069492 xref: EMBL:BC101593 xref: EMBL:BC112140 xref: EMBL:X57130 xref: HGNC:HGNC:4715 xref: UniGene:Hs.150206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005863 ! H11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004742 name: HIST1H1E_human def: "Histone H1.4 gene" [UniProtKB:P10412] synonym: "H1F4" EXACT [UniProtKB:P10412] xref: EMBL:AF531302 xref: EMBL:AL353759 xref: EMBL:BC096168 xref: EMBL:BC096169 xref: EMBL:BC099632 xref: EMBL:M60748 xref: HGNC:HGNC:4718 xref: UniGene:Hs.248133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005838 ! H14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004743 name: H2AFX_human def: "Histone H2A.x gene" [UniProtKB:P16104] synonym: "H2AX" EXACT [UniProtKB:P16104] xref: EMBL:BC004915 xref: EMBL:BC011694 xref: EMBL:BC013416 xref: EMBL:CR457079 xref: EMBL:DQ015918 xref: EMBL:X14850 xref: HGNC:HGNC:4739 xref: UniGene:Hs.477879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001526 ! H2AX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004744 name: HIST1H2BC_human def: "Histone H2B type 1-C/E/F/G/I gene" [UniProtKB:P62807] synonym: "H2BFL" EXACT [UniProtKB:P62807] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005771 ! H2B1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004745 name: HIST1H2BE_human def: "Histone H2B type 1-C/E/F/G/I gene" [UniProtKB:P62807] synonym: "H2BFH" EXACT [UniProtKB:P62807] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005771 ! H2B1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004746 name: HIST1H2BF_human def: "Histone H2B type 1-C/E/F/G/I gene" [UniProtKB:P62807] synonym: "H2BFG" EXACT [UniProtKB:P62807] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005771 ! H2B1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004747 name: HIST1H2BG_human def: "Histone H2B type 1-C/E/F/G/I gene" [UniProtKB:P62807] synonym: "H2BFA" EXACT [UniProtKB:P62807] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005771 ! H2B1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004748 name: HIST1H2BI_human def: "Histone H2B type 1-C/E/F/G/I gene" [UniProtKB:P62807] synonym: "H2BFK" EXACT [UniProtKB:P62807] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005771 ! H2B1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004749 name: HIST1H3A_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FA" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004750 name: HIST1H3B_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FL" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004751 name: HIST1H3C_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FC" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004752 name: HIST1H3D_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FB" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004753 name: HIST1H3E_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FD" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004754 name: HIST1H3F_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FI" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004755 name: HIST1H3G_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FH" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004756 name: HIST1H3H_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FK" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004757 name: HIST1H3I_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FF" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004758 name: HIST1H3J_human def: "Histone H3.1 gene" [UniProtKB:P68431] synonym: "H3FJ" EXACT [UniProtKB:P68431] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005221 ! H31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004759 name: HIST2H3A_human def: "Histone H3.2 gene" [UniProtKB:Q71DI3] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005285 ! H32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004760 name: HIST2H3C_human def: "Histone H3.2 gene" [UniProtKB:Q71DI3] synonym: "H3F2" EXACT [UniProtKB:Q71DI3] synonym: "H3FM" EXACT [UniProtKB:Q71DI3] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005285 ! H32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004761 name: H3F3A_human def: "Histone H3.3 gene" [UniProtKB:P84243] synonym: "H3.3A" EXACT [UniProtKB:P84243] synonym: "H3F3" EXACT [UniProtKB:P84243] synonym: "PP781" EXACT [UniProtKB:P84243] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005927 ! H33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004762 name: H3F3B_human def: "Histone H3.3 gene" [UniProtKB:P84243] synonym: "H3.3B" EXACT [UniProtKB:P84243] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005927 ! H33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004763 name: HIST1H4A_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/A" EXACT [UniProtKB:P62805] synonym: "H4FA" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004764 name: HIST1H4B_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/I" EXACT [UniProtKB:P62805] synonym: "H4FI" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004765 name: HIST1H4C_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/G" EXACT [UniProtKB:P62805] synonym: "H4FG" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004766 name: HIST1H4D_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/B" EXACT [UniProtKB:P62805] synonym: "H4FB" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004767 name: HIST1H4E_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/J" EXACT [UniProtKB:P62805] synonym: "H4FJ" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004768 name: HIST1H4F_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/C" EXACT [UniProtKB:P62805] synonym: "H4FC" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004769 name: HIST1H4H_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/H" EXACT [UniProtKB:P62805] synonym: "H4FH" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004770 name: HIST1H4I_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/M" EXACT [UniProtKB:P62805] synonym: "H4FM" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004771 name: HIST1H4J_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/E" EXACT [UniProtKB:P62805] synonym: "H4FE" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004772 name: HIST1H4K_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/D" EXACT [UniProtKB:P62805] synonym: "H4FD" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004773 name: HIST1H4L_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/K" EXACT [UniProtKB:P62805] synonym: "H4FK" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004774 name: HIST2H4A_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/N" EXACT [UniProtKB:P62805] synonym: "H4F2" EXACT [UniProtKB:P62805] synonym: "H4FN" EXACT [UniProtKB:P62805] synonym: "HIST2H4" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004775 name: HIST4H4_human def: "Histone H4 gene" [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004776 name: HLA-DQA1_human def: "HLA class II histocompatibility antigen, DQ(3) alpha chain precursor gene" [UniProtKB:P01909] xref: EMBL:AL662789 xref: EMBL:AM042559 xref: EMBL:AY663395 xref: EMBL:AY663406 xref: EMBL:AY663411 xref: EMBL:AY663413 xref: EMBL:BC008585 xref: EMBL:DQ178400 xref: EMBL:DQ178401 xref: EMBL:DQ178402 xref: EMBL:DQ178403 xref: EMBL:M17846 xref: EMBL:M20431 xref: EMBL:M20506 xref: EMBL:M34997 xref: EMBL:M34999 xref: EMBL:U03675 xref: EMBL:U92032 xref: EMBL:X00370 xref: EMBL:X00452 xref: EMBL:Z84489 xref: HGNC:HGNC:4942 xref: UniGene:Hs.387679 xref: UniGene:Hs.591798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006147 ! HA23_HUMAN relationship: codes_for CCO:B0063248 ! HA25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004777 name: HAP1_human def: "Huntingtin-associated protein 1 gene" [UniProtKB:P54257] synonym: "HAP2" EXACT [UniProtKB:P54257] synonym: "HLP1" EXACT [UniProtKB:P54257] xref: EMBL:AF040723 xref: EMBL:AJ012824 xref: EMBL:AJ224877 xref: EMBL:AK022007 xref: EMBL:U38371 xref: HGNC:HGNC:4812 xref: UniGene:Hs.158300 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006153 ! HAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004778 name: GSG2_human def: "Serine/threonine-protein kinase haspin gene" [UniProtKB:Q8TF76] xref: EMBL:AB039834 xref: EMBL:AF289865 xref: EMBL:AK056691 xref: EMBL:BC047457 xref: HGNC:HGNC:19682 xref: UniGene:Hs.534059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001999 ! HASP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004779 name: HBA1_human def: "Hemoglobin subunit alpha gene" [UniProtKB:P69905] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006221 ! HBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004780 name: HBA2_human def: "Hemoglobin subunit alpha gene" [UniProtKB:P69905] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006221 ! HBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004781 name: HBP1_human def: "HMG box-containing protein 1 gene" [UniProtKB:O60381] xref: EMBL:AC004492 xref: EMBL:AF182038 xref: EMBL:AK074353 xref: EMBL:BC017069 xref: EMBL:BC022329 xref: HGNC:HGNC:23200 xref: UniGene:Hs.162032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001407 ! HBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004782 name: HCFC1_human def: "Host cell factor gene" [UniProtKB:P51610] synonym: "HCF1" EXACT [UniProtKB:P51610] synonym: "HFC1" EXACT [UniProtKB:P51610] xref: EMBL:BC063435 xref: EMBL:L20010 xref: EMBL:U52112 xref: EMBL:X79198 xref: HGNC:HGNC:4839 xref: UniGene:Hs.83634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001650 ! HCFC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004783 name: HCK_human def: "Tyrosine-protein kinase HCK gene" [UniProtKB:P08631] xref: EMBL:AK026432 xref: EMBL:AL049539 xref: EMBL:AL353092 xref: EMBL:BC014435 xref: EMBL:BC094847 xref: EMBL:BC108930 xref: EMBL:BC108931 xref: EMBL:BC113854 xref: EMBL:BC114463 xref: EMBL:M16591 xref: EMBL:M16592 xref: EMBL:X58741 xref: EMBL:X58742 xref: EMBL:X58743 xref: HGNC:HGNC:4840 xref: UniGene:Hs.655210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005894 ! HCK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004784 name: HDAC10_human def: "Histone deacetylase 10 gene" [UniProtKB:Q969S8] xref: EMBL:AF393962 xref: EMBL:AF407272 xref: EMBL:AF407273 xref: EMBL:AF426160 xref: EMBL:AL022328 xref: EMBL:AL512711 xref: EMBL:AY450395 xref: EMBL:BC125083 xref: EMBL:CR456465 xref: HGNC:HGNC:18128 xref: UniGene:Hs.26593 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005341 ! HDA10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004785 name: HDAC11_human def: "Histone deacetylase 11 gene" [UniProtKB:Q96DB2] xref: EMBL:AK025426 xref: EMBL:AK025890 xref: EMBL:AL137362 xref: EMBL:BC009676 xref: HGNC:HGNC:19086 xref: UniGene:Hs.661908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005701 ! HDA11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004786 name: HDAC1_human def: "Histone deacetylase 1 gene" [UniProtKB:Q13547] synonym: "RPD3L1" EXACT [UniProtKB:Q13547] xref: EMBL:BC000301 xref: EMBL:D50405 xref: EMBL:U50079 xref: HGNC:HGNC:4852 xref: UniGene:Hs.88556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005484 ! HDAC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004787 name: HDAC2_human def: "Histone deacetylase 2 gene" [UniProtKB:Q92769] xref: EMBL:AL590398 xref: EMBL:AL671967 xref: EMBL:BC031055 xref: EMBL:U31814 xref: HGNC:HGNC:4853 xref: UniGene:Hs.3352 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005343 ! HDAC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004788 name: HDAC3_human def: "Histone deacetylase 3 gene" [UniProtKB:O15379] xref: EMBL:AF005482 xref: EMBL:AF039703 xref: EMBL:AF053137 xref: EMBL:AF053138 xref: EMBL:AF053139 xref: EMBL:AF059650 xref: EMBL:BC000614 xref: EMBL:U66914 xref: EMBL:U75696 xref: EMBL:U75697 xref: HGNC:HGNC:4854 xref: UniGene:Hs.519632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001376 ! HDAC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004789 name: HDAC4_human def: "Histone deacetylase 4 gene" [UniProtKB:P56524] synonym: "KIAA0288" EXACT [UniProtKB:P56524] xref: EMBL:AB006626 xref: EMBL:AF132607 xref: HGNC:HGNC:14063 xref: UniGene:Hs.20516 xref: UniGene:Hs.688314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001679 ! HDAC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004790 name: HDAC5_human def: "Histone deacetylase 5 gene" [UniProtKB:Q9UQL6] synonym: "KIAA0600" EXACT [UniProtKB:Q9UQL6] xref: EMBL:AB011172 xref: EMBL:AF039691 xref: EMBL:AF132608 xref: EMBL:BC013140 xref: EMBL:BC051824 xref: EMBL:BK000028 xref: HGNC:HGNC:14068 xref: UniGene:Hs.438782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002244 ! HDAC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004791 name: HDAC6_human def: "Histone deacetylase 6 gene" [UniProtKB:Q9UBN7] synonym: "JM21" EXACT [UniProtKB:Q9UBN7] synonym: "KIAA0901" EXACT [UniProtKB:Q9UBN7] xref: EMBL:AB020708 xref: EMBL:AF132609 xref: EMBL:AJ011972 xref: EMBL:BC013737 xref: EMBL:CH471224 xref: HGNC:HGNC:14064 xref: UniGene:Hs.6764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002192 ! HDAC6_HUMAN relationship: codes_for CCO:B0038585 ! Q7L3E5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004793 name: HDAC9_human def: "Histone deacetylase 9 gene" [UniProtKB:Q9UKV0] synonym: "HDAC7" EXACT [UniProtKB:Q9UKV0] synonym: "HDAC7B" EXACT [UniProtKB:Q9UKV0] synonym: "HDRP" EXACT [UniProtKB:Q9UKV0] synonym: "KIAA0744" EXACT [UniProtKB:Q9UKV0] synonym: "MITR" EXACT [UniProtKB:Q9UKV0] xref: EMBL:AB018287 xref: EMBL:AC004994 xref: EMBL:AF124924 xref: EMBL:AJ459808 xref: EMBL:AY032737 xref: EMBL:AY032738 xref: EMBL:AY197371 xref: EMBL:BC111735 xref: HGNC:HGNC:14065 xref: UniGene:Hs.196054 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002222 ! HDAC9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004796 name: HEPACAM_human def: "Hepatocyte cell adhesion molecule precursor gene" [UniProtKB:Q14CZ8] xref: EMBL:AK098396 xref: EMBL:AK122595 xref: EMBL:AL834419 xref: EMBL:AY047587 xref: EMBL:BC104831 xref: EMBL:BC113562 xref: HGNC:HGNC:26361 xref: UniGene:Hs.159863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001796 ! HECAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004797 name: HECTD3_human def: "Probable E3 ubiquitin-protein ligase HECTD3 gene" [UniProtKB:Q5T447] xref: EMBL:AK024809 xref: EMBL:AL359473 xref: EMBL:BC019105 xref: HGNC:HGNC:26117 xref: UniGene:Hs.525084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001875 ! HECD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004798 name: HECW1_human def: "E3 ubiquitin-protein ligase HECW1 gene" [UniProtKB:Q76N89] synonym: "KIAA0322" EXACT [UniProtKB:Q76N89] synonym: "NEDL1" EXACT [UniProtKB:Q76N89] xref: EMBL:AB002320 xref: EMBL:AB048365 xref: HGNC:HGNC:22195 xref: UniGene:Hs.164453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005962 ! HECW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004799 name: HELLS_human def: "Lymphoid-specific helicase gene" [UniProtKB:Q9NRZ9] synonym: "Nbla10143" EXACT [UniProtKB:Q9NRZ9] synonym: "PASG" EXACT [UniProtKB:Q9NRZ9] synonym: "SMARCA6" EXACT [UniProtKB:Q9NRZ9] xref: EMBL:AB074174 xref: EMBL:AB102717 xref: EMBL:AB102718 xref: EMBL:AB102719 xref: EMBL:AB102720 xref: EMBL:AB102721 xref: EMBL:AB102722 xref: EMBL:AB113249 xref: EMBL:AF155827 xref: EMBL:AL138759 xref: EMBL:AY007108 xref: EMBL:BC015477 xref: EMBL:BC029381 xref: EMBL:BC030963 xref: EMBL:BC031004 xref: EMBL:BX538033 xref: HGNC:HGNC:4861 xref: UniGene:Hs.655830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002161 ! HELLS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004800 name: HERC5_human def: "Probable E3 ubiquitin-protein ligase HERC5 gene" [UniProtKB:Q9UII4] synonym: "CEB1" EXACT [UniProtKB:Q9UII4] synonym: "CEBP1" EXACT [UniProtKB:Q9UII4] xref: EMBL:AB027289 xref: HGNC:HGNC:24368 xref: UniGene:Hs.26663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002206 ! HERC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004801 name: HEXIM1_human def: "Protein HEXIM1 gene" [UniProtKB:O94992] synonym: "CLP1" EXACT [UniProtKB:O94992] synonym: "EDG1" EXACT [UniProtKB:O94992] synonym: "HIS1" EXACT [UniProtKB:O94992] synonym: "MAQ1" EXACT [UniProtKB:O94992] xref: EMBL:AB021179 xref: EMBL:BC006460 xref: HGNC:HGNC:24953 xref: UniGene:Hs.15299 xref: UniGene:Hs.586945 xref: UniGene:Hs.634944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001445 ! HEXI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004802 name: HEXIM2_human def: "Protein HEXIM2 gene" [UniProtKB:Q96MH2] synonym: "L3" EXACT [UniProtKB:Q96MH2] xref: EMBL:AK056946 xref: EMBL:AY598322 xref: EMBL:BC003531 xref: EMBL:BC012474 xref: EMBL:BC025970 xref: EMBL:CH471178 xref: HGNC:HGNC:28591 xref: UniGene:Hs.56382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002049 ! HEXI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004803 name: HGF_human def: "Hepatocyte growth factor precursor gene" [UniProtKB:P14210] synonym: "HPTA" EXACT [UniProtKB:P14210] xref: EMBL:AC004960 xref: EMBL:AY246560 xref: EMBL:BC022308 xref: EMBL:BC063485 xref: EMBL:BC130284 xref: EMBL:BC130286 xref: EMBL:CH236949 xref: EMBL:D90334 xref: EMBL:L02931 xref: EMBL:M29145 xref: EMBL:M55379 xref: EMBL:M60718 xref: EMBL:M73239 xref: EMBL:M73240 xref: EMBL:M75966 xref: EMBL:M75967 xref: EMBL:M75968 xref: EMBL:M75969 xref: EMBL:M75971 xref: EMBL:M75972 xref: EMBL:M75973 xref: EMBL:M75974 xref: EMBL:M75975 xref: EMBL:M75976 xref: EMBL:M75977 xref: EMBL:M75978 xref: EMBL:M75979 xref: EMBL:M75980 xref: EMBL:M75981 xref: EMBL:M75982 xref: EMBL:M75983 xref: EMBL:M77227 xref: EMBL:U46010 xref: EMBL:X16323 xref: EMBL:X57574 xref: HGNC:HGNC:4893 xref: UniGene:Hs.396530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001518 ! HGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004804 name: HGS_human def: "Hepatocyte growth factor-regulated tyrosine kinase substrate gene" [UniProtKB:O14964] synonym: "HRS" EXACT [UniProtKB:O14964] xref: EMBL:AF260566 xref: EMBL:BC003565 xref: EMBL:BT009754 xref: EMBL:D84064 xref: EMBL:U43895 xref: HGNC:HGNC:4897 xref: UniGene:Hs.514590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005280 ! HGS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004805 name: HIC1_human def: "Hypermethylated in cancer 1 protein gene" [UniProtKB:Q14526] synonym: "ZBTB29" EXACT [UniProtKB:Q14526] xref: EMBL:L41919 xref: HGNC:HGNC:4909 xref: UniGene:Hs.695682 xref: UniGene:Hs.706722 xref: UniGene:Hs.72956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001783 ! HIC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004806 name: HIF1A_human def: "Hypoxia-inducible factor 1 alpha gene" [UniProtKB:Q16665] synonym: "MOP1" EXACT [UniProtKB:Q16665] xref: EMBL:AB073325 xref: EMBL:AF050115 xref: EMBL:AF050116 xref: EMBL:AF050117 xref: EMBL:AF050118 xref: EMBL:AF050119 xref: EMBL:AF050120 xref: EMBL:AF050121 xref: EMBL:AF050122 xref: EMBL:AF050123 xref: EMBL:AF050124 xref: EMBL:AF050125 xref: EMBL:AF050126 xref: EMBL:AF050127 xref: EMBL:AF207601 xref: EMBL:AF207602 xref: EMBL:AF208487 xref: EMBL:AF304431 xref: EMBL:AL137129 xref: EMBL:BC012527 xref: EMBL:BT009776 xref: EMBL:CH471061 xref: EMBL:U22431 xref: EMBL:U29165 xref: HGNC:HGNC:4910 xref: UniGene:Hs.597216 xref: UniGene:Hs.654600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005430 ! HIF1A_HUMAN relationship: codes_for CCO:B0042415 ! A8MYV6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004807 name: HIP1_human def: "Huntingtin-interacting protein 1 gene" [UniProtKB:O00291] xref: EMBL:AC004491 xref: EMBL:AC018720 xref: EMBL:AF052261 xref: EMBL:AF052262 xref: EMBL:AF052263 xref: EMBL:AF052264 xref: EMBL:AF052265 xref: EMBL:AF052266 xref: EMBL:AF052267 xref: EMBL:AF052268 xref: EMBL:AF052269 xref: EMBL:AF052270 xref: EMBL:AF052271 xref: EMBL:AF052272 xref: EMBL:AF052273 xref: EMBL:AF052274 xref: EMBL:AF052275 xref: EMBL:AF052276 xref: EMBL:AF052277 xref: EMBL:AF052278 xref: EMBL:AF052279 xref: EMBL:AF052280 xref: EMBL:AF052281 xref: EMBL:AF052282 xref: EMBL:AF052283 xref: EMBL:AF052284 xref: EMBL:AF052285 xref: EMBL:AF052286 xref: EMBL:AF052287 xref: EMBL:AF052288 xref: EMBL:AF365404 xref: EMBL:BC110545 xref: EMBL:U79734 xref: EMBL:Y09420 xref: HGNC:HGNC:4913 xref: UniGene:Hs.329266 xref: UniGene:Hs.619089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006214 ! HIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004808 name: HIPK1_human def: "Homeodomain-interacting protein kinase 1 gene" [UniProtKB:Q86Z02] synonym: "KIAA0630" EXACT [UniProtKB:Q86Z02] xref: EMBL:AB014530 xref: EMBL:AB089957 xref: EMBL:AL137856 xref: EMBL:AL833829 xref: EMBL:BC028408 xref: EMBL:BC033012 xref: EMBL:BC036057 xref: EMBL:CH471122 xref: HGNC:HGNC:19006 xref: UniGene:Hs.532363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005675 ! HIPK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004809 name: HIPK2_human def: "Homeodomain-interacting protein kinase 2 gene" [UniProtKB:Q9H2X6] xref: EMBL:AC005531 xref: EMBL:AC006021 xref: EMBL:AC073184 xref: EMBL:AC141932 xref: EMBL:AF207702 xref: EMBL:AF208291 xref: EMBL:AF326592 xref: HGNC:HGNC:14402 xref: UniGene:Hs.397465 xref: UniGene:Hs.632033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002130 ! HIPK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004810 name: HMG20A_human def: "High mobility group protein 20A gene" [UniProtKB:Q9NP66] synonym: "HMGX1" EXACT [UniProtKB:Q9NP66] xref: EMBL:AC142496 xref: EMBL:AF146222 xref: EMBL:AK001601 xref: EMBL:AK223100 xref: EMBL:AL355736 xref: EMBL:AL355737 xref: EMBL:BC021959 xref: EMBL:BT006716 xref: EMBL:CH471136 xref: HGNC:HGNC:5001 xref: UniGene:Hs.69594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005296 ! HM20A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004811 name: HMG20B_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related gene" [UniProtKB:Q9P0W2] synonym: "BRAF35" EXACT [UniProtKB:Q9P0W2] synonym: "HMGX2" EXACT [UniProtKB:Q9P0W2] synonym: "SMARCE1R" EXACT [UniProtKB:Q9P0W2] xref: EMBL:AC005786 xref: EMBL:AF072165 xref: EMBL:AF072836 xref: EMBL:AF146223 xref: EMBL:AF288679 xref: EMBL:AF331191 xref: EMBL:AK090733 xref: EMBL:AL355709 xref: EMBL:BC002552 xref: EMBL:BC003505 xref: EMBL:BC004408 xref: EMBL:BC021585 xref: EMBL:CR456754 xref: HGNC:HGNC:5002 xref: UniGene:Hs.406534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002184 ! HM20B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004812 name: HMGB1_human def: "High mobility group protein B1 gene" [UniProtKB:P09429] synonym: "HMG1" EXACT [UniProtKB:P09429] xref: EMBL:AK122825 xref: EMBL:AK291494 xref: EMBL:AL353648 xref: EMBL:AY377859 xref: EMBL:BC003378 xref: EMBL:BC030981 xref: EMBL:BC066889 xref: EMBL:BC067732 xref: EMBL:BC141844 xref: EMBL:BT006940 xref: EMBL:BT020159 xref: EMBL:CH471075 xref: EMBL:CR456863 xref: EMBL:CR749614 xref: EMBL:D63874 xref: EMBL:EF157968 xref: EMBL:EU012027 xref: EMBL:U51677 xref: EMBL:X12597 xref: HGNC:HGNC:4983 xref: UniGene:Hs.434102 xref: UniGene:Hs.593339 xref: UniGene:Hs.644368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005929 ! HMGB1_HUMAN relationship: codes_for CCO:B0050274 ! Q5T7C4_HUMAN relationship: codes_for CCO:B0050289 ! Q5T7C6_HUMAN relationship: codes_for CCO:B0050299 ! Q5T7C0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004813 name: HMOX2_human def: "Heme oxygenase 2 gene" [UniProtKB:P30519] synonym: "HO2" EXACT [UniProtKB:P30519] xref: EMBL:AC007606 xref: EMBL:AF051306 xref: EMBL:AY771350 xref: EMBL:BC002396 xref: EMBL:BT019788 xref: EMBL:CH471112 xref: EMBL:D21243 xref: EMBL:S34389 xref: HGNC:HGNC:5014 xref: UniGene:Hs.284279 xref: UniGene:Hs.307043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006148 ! HMOX2_HUMAN relationship: codes_for CCO:B0054019 ! A8MT35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004820 name: RBMX_human def: "Heterogeneous nuclear ribonucleoprotein G gene" [UniProtKB:P38159] synonym: "HNRPG" EXACT [UniProtKB:P38159] synonym: "RBMXP1" EXACT [UniProtKB:P38159] xref: EMBL:AF266720 xref: EMBL:AF266721 xref: EMBL:AF266722 xref: EMBL:AF266723 xref: EMBL:AL683813 xref: EMBL:AY464692 xref: EMBL:BC006550 xref: EMBL:BC007435 xref: EMBL:Z23064 xref: HGNC:HGNC:9910 xref: UniGene:Hs.380118 xref: UniGene:Hs.699781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005256 ! HNRPG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004823 name: HOOK1_human def: "Protein Hook homolog 1 gene" [UniProtKB:Q9UJC3] xref: EMBL:AC113175 xref: EMBL:AF044923 xref: EMBL:AL035416 xref: EMBL:BC011621 xref: HGNC:HGNC:19884 xref: UniGene:Hs.378836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005594 ! HOOK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004824 name: HORMAD1_human def: "HORMA domain-containing protein 1 gene" [UniProtKB:Q86X24] synonym: "NOHMA" EXACT [UniProtKB:Q86X24] xref: EMBL:AL136755 xref: EMBL:AL356292 xref: EMBL:AY626344 xref: EMBL:BC033014 xref: EMBL:BC047406 xref: EMBL:CR533505 xref: HGNC:HGNC:25245 xref: UniGene:Hs.298312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001340 ! A6NMK2_HUMAN relationship: codes_for CCO:B0001942 ! HORM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004825 name: HORMAD2_human def: "HORMA domain-containing protein 2 gene" [UniProtKB:Q8N7B1] xref: EMBL:AK098703 xref: EMBL:BC030013 xref: EMBL:CR456341 xref: HGNC:HGNC:28383 xref: UniGene:Hs.120391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001967 ! HORM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004826 name: HSPBP1_human def: "Hsp70-binding protein 1 gene" [UniProtKB:Q9NZL4] synonym: "HSPBP" EXACT [UniProtKB:Q9NZL4] synonym: "PP1845" EXACT [UniProtKB:Q9NZL4] xref: EMBL:AB020592 xref: EMBL:AF093420 xref: EMBL:AF187859 xref: EMBL:AF217996 xref: EMBL:AK130636 xref: EMBL:BC001236 xref: EMBL:BC002373 xref: EMBL:CR457118 xref: UniGene:Hs.53066 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005199 ! HPBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004827 name: HPS6_human def: "Hermansky-Pudlak syndrome 6 protein gene" [UniProtKB:Q86YV9] xref: EMBL:AF536238 xref: EMBL:AK026154 xref: EMBL:BC011594 xref: EMBL:BC014993 xref: HGNC:HGNC:18817 xref: UniGene:Hs.125133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006286 ! HPS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004828 name: HRASLS3_human def: "HRAS-like suppressor 3 gene" [UniProtKB:P53816] synonym: "HREV107" EXACT [UniProtKB:P53816] xref: EMBL:AB030814 xref: EMBL:AF317086 xref: EMBL:BC001387 xref: EMBL:BC103807 xref: EMBL:X92814 xref: HGNC:HGNC:17825 xref: UniGene:Hs.502775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001666 ! HRSL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004829 name: MLL_human def: "Histone-lysine N-methyltransferase HRX gene" [UniProtKB:Q03164] synonym: "ALL1" EXACT [UniProtKB:Q03164] synonym: "CXXC7" EXACT [UniProtKB:Q03164] synonym: "HRX" EXACT [UniProtKB:Q03164] synonym: "HTRX" EXACT [UniProtKB:Q03164] synonym: "KMT2A" EXACT [UniProtKB:Q03164] synonym: "TRX1" EXACT [UniProtKB:Q03164] xref: EMBL:AF231998 xref: EMBL:AY373585 xref: EMBL:D14540 xref: EMBL:L01986 xref: EMBL:L04284 xref: EMBL:L04731 xref: EMBL:S66432 xref: EMBL:S78570 xref: EMBL:U04737 xref: EMBL:X83604 xref: EMBL:Z69744 xref: EMBL:Z69745 xref: EMBL:Z69746 xref: EMBL:Z69747 xref: EMBL:Z69748 xref: EMBL:Z69749 xref: EMBL:Z69750 xref: EMBL:Z69751 xref: EMBL:Z69752 xref: EMBL:Z69753 xref: EMBL:Z69754 xref: EMBL:Z69755 xref: EMBL:Z69756 xref: EMBL:Z69757 xref: EMBL:Z69758 xref: EMBL:Z69759 xref: EMBL:Z69760 xref: EMBL:Z69761 xref: EMBL:Z69762 xref: EMBL:Z69763 xref: EMBL:Z69764 xref: EMBL:Z69765 xref: EMBL:Z69766 xref: EMBL:Z69767 xref: EMBL:Z69768 xref: EMBL:Z69769 xref: EMBL:Z69770 xref: EMBL:Z69772 xref: EMBL:Z69773 xref: EMBL:Z69774 xref: EMBL:Z69775 xref: EMBL:Z69776 xref: EMBL:Z69777 xref: EMBL:Z69778 xref: EMBL:Z69779 xref: EMBL:Z69780 xref: HGNC:HGNC:7132 xref: UniGene:Hs.258855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005486 ! HRX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004830 name: HSP90AA1_human def: "Heat shock protein HSP 90-alpha gene" [UniProtKB:P07900] synonym: "HSP90A" EXACT [UniProtKB:P07900] synonym: "HSPC1" EXACT [UniProtKB:P07900] synonym: "HSPCA" EXACT [UniProtKB:P07900] xref: EMBL:AJ890082 xref: EMBL:AJ890083 xref: EMBL:BC000987 xref: EMBL:BC121062 xref: EMBL:D87666 xref: EMBL:DQ314871 xref: EMBL:M27024 xref: EMBL:M30626 xref: EMBL:X07270 xref: EMBL:X15183 xref: HGNC:HGNC:5253 xref: UniGene:Hs.523560 xref: UniGene:Hs.525600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005698 ! HS90A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004831 name: HSP90AB1_human def: "Heat shock protein HSP 90-beta gene" [UniProtKB:P08238] synonym: "HSP90B" EXACT [UniProtKB:P08238] synonym: "HSPC2" EXACT [UniProtKB:P08238] synonym: "HSPCB" EXACT [UniProtKB:P08238] xref: EMBL:AF275719 xref: EMBL:AL136543 xref: EMBL:AL139392 xref: EMBL:AY359878 xref: EMBL:BC004928 xref: EMBL:BC009206 xref: EMBL:BC012807 xref: EMBL:BC014485 xref: EMBL:BC016753 xref: EMBL:BC068474 xref: EMBL:DQ314872 xref: EMBL:J04988 xref: EMBL:M16660 xref: EMBL:S70561 xref: HGNC:HGNC:5258 xref: UniGene:Hs.509736 xref: UniGene:Hs.696394 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005580 ! HS90B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004832 name: HSF4_human def: "Heat shock factor protein 4 gene" [UniProtKB:Q9ULV5] xref: EMBL:AB029347 xref: EMBL:AB029348 xref: EMBL:D87673 xref: HGNC:HGNC:5227 xref: UniGene:Hs.512156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006048 ! HSF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004833 name: PRM1_human def: "Sperm protamine-P1 gene" [UniProtKB:P04553] xref: EMBL:AF215707 xref: EMBL:BC003673 xref: EMBL:BT006746 xref: EMBL:M29706 xref: EMBL:M60331 xref: EMBL:S68144 xref: EMBL:U15422 xref: EMBL:Y00443 xref: EMBL:Z46940 xref: HGNC:HGNC:9447 xref: UniGene:Hs.2909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001481 ! HSP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004834 name: HSPA1A_human def: "Heat shock 70 kDa protein 1 gene" [UniProtKB:P08107] synonym: "HSPA1" EXACT [UniProtKB:P08107] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005822 ! HSP71_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004835 name: HSPA1B_human def: "Heat shock 70 kDa protein 1 gene" [UniProtKB:P08107] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005822 ! HSP71_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004836 name: HSPA2_human def: "Heat shock-related 70 kDa protein 2 gene" [UniProtKB:P54652] xref: EMBL:BC001752 xref: EMBL:BC036107 xref: EMBL:BT009815 xref: EMBL:DQ489378 xref: EMBL:L26336 xref: EMBL:U10149 xref: EMBL:U56725 xref: HGNC:HGNC:5235 xref: UniGene:Hs.432648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001670 ! HSP72_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004837 name: HSPA7_human def: "Putative heat shock 70 kDa protein 7 gene" [UniProtKB:P48741] synonym: "HSP70B" EXACT [UniProtKB:P48741] xref: EMBL:AL451067 xref: EMBL:M11236 xref: HGNC:HGNC:5240 xref: UniGene:Hs.662180 xref: UniGene:Hs.690634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063206 ! HSP77_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004838 name: HSPA8_human def: "Heat shock cognate 71 kDa protein gene" [UniProtKB:P11142] synonym: "HSC70" EXACT [UniProtKB:P11142] synonym: "HSP73" EXACT [UniProtKB:P11142] synonym: "HSPA10" EXACT [UniProtKB:P11142] xref: EMBL:AB034951 xref: EMBL:AF352832 xref: EMBL:BC016179 xref: EMBL:BC016660 xref: EMBL:BC019816 xref: EMBL:Y00371 xref: HGNC:HGNC:5241 xref: UniGene:Hs.702021 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005699 ! HSP7C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004839 name: HSPB1_human def: "Heat shock protein beta-1 gene" [UniProtKB:P04792] synonym: "HSP27" EXACT [UniProtKB:P04792] synonym: "HSP28" EXACT [UniProtKB:P04792] xref: EMBL:AB020027 xref: EMBL:AC006388 xref: EMBL:BC000510 xref: EMBL:BC012292 xref: EMBL:BC012768 xref: EMBL:BC014920 xref: EMBL:BC073768 xref: EMBL:BT019888 xref: EMBL:CR407614 xref: EMBL:CR536489 xref: EMBL:DQ379985 xref: EMBL:L39370 xref: EMBL:S74571 xref: EMBL:U90906 xref: EMBL:X16477 xref: EMBL:X54079 xref: EMBL:Z23090 xref: HGNC:HGNC:5246 xref: UniGene:Hs.520973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005842 ! HSPB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004840 name: HSPB3_human def: "Heat shock protein beta-3 gene" [UniProtKB:Q12988] synonym: "HSPL27" EXACT [UniProtKB:Q12988] xref: EMBL:U15590 xref: EMBL:Y17782 xref: HGNC:HGNC:5248 xref: UniGene:Hs.41707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006197 ! HSPB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004841 name: HSPB9_human def: "Heat shock protein beta-9 gene" [UniProtKB:Q9BQS6] xref: EMBL:AJ302068 xref: EMBL:BC093991 xref: EMBL:BC093993 xref: HGNC:HGNC:30589 xref: UniGene:Hs.620611 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005333 ! HSPB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004842 name: HTATIP2_human def: "Oxidoreductase HTATIP2 gene" [UniProtKB:Q9BUP3] synonym: "CC3" EXACT [UniProtKB:Q9BUP3] synonym: "TIP30" EXACT [UniProtKB:Q9BUP3] xref: EMBL:AF039103 xref: EMBL:AF092095 xref: EMBL:AK222969 xref: EMBL:AK223010 xref: EMBL:BC002439 xref: EMBL:BC015358 xref: EMBL:CR456821 xref: EMBL:U69161 xref: HGNC:HGNC:16637 xref: UniGene:Hs.90753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002098 ! HTAI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004843 name: HUS1_human def: "Checkpoint protein HUS1 gene" [UniProtKB:O60921] xref: EMBL:AF076844 xref: EMBL:AF110393 xref: EMBL:AF503165 xref: EMBL:BC007013 xref: EMBL:BT019481 xref: EMBL:BT019482 xref: EMBL:CR536552 xref: EMBL:Y16893 xref: HGNC:HGNC:5309 xref: UniGene:Hs.152983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001419 ! HUS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004844 name: HUWE1_human def: "E3 ubiquitin-protein ligase HUWE1 gene" [UniProtKB:Q7Z6Z7] synonym: "HSPC272" EXACT [UniProtKB:Q7Z6Z7] synonym: "KIAA0312" EXACT [UniProtKB:Q7Z6Z7] synonym: "KIAA1578" EXACT [UniProtKB:Q7Z6Z7] synonym: "UREB1" EXACT [UniProtKB:Q7Z6Z7] xref: EMBL:AB002310 xref: EMBL:AB046798 xref: EMBL:AB071605 xref: EMBL:AF057569 xref: EMBL:AF161390 xref: EMBL:AL162050 xref: EMBL:AL592046 xref: EMBL:AY772009 xref: EMBL:AY929612 xref: EMBL:BC002602 xref: EMBL:BC063505 xref: EMBL:CR456813 xref: EMBL:DQ097177 xref: EMBL:Z94044 xref: EMBL:Z97054 xref: HGNC:HGNC:30892 xref: UniGene:Hs.136905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005709 ! HUWE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004845 name: HOXC10_human def: "Homeobox protein Hox-C10 gene" [UniProtKB:Q9NYD6] synonym: "HOX3I" EXACT [UniProtKB:Q9NYD6] xref: EMBL:AF255675 xref: EMBL:BC001293 xref: EMBL:X99684 xref: EMBL:X99685 xref: HGNC:HGNC:5122 xref: UniGene:Hs.44276 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005451 ! HXC10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004847 name: ICAM1_human def: "Intercellular adhesion molecule 1 precursor gene" [UniProtKB:P05362] xref: EMBL:AF340039 xref: EMBL:AY225514 xref: EMBL:BC015969 xref: EMBL:BT006854 xref: EMBL:J03132 xref: EMBL:M24283 xref: EMBL:X06990 xref: EMBL:X57151 xref: EMBL:X59286 xref: EMBL:X59287 xref: EMBL:X59288 xref: HGNC:HGNC:5344 xref: UniGene:Hs.643447 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005450 ! ICAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004848 name: ID2_human def: "DNA-binding protein inhibitor ID-2 gene" [UniProtKB:Q02363] xref: EMBL:BC030639 xref: EMBL:D13891 xref: EMBL:M97796 xref: HGNC:HGNC:5361 xref: UniGene:Hs.180919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006149 ! ID2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004849 name: ID3_human def: "DNA-binding protein inhibitor ID-3 gene" [UniProtKB:Q02535] synonym: "1R21" EXACT [UniProtKB:Q02535] synonym: "HEIR-1" EXACT [UniProtKB:Q02535] xref: EMBL:AL021154 xref: EMBL:BC003107 xref: EMBL:BT006791 xref: EMBL:X66924 xref: EMBL:X69111 xref: EMBL:X73428 xref: HGNC:HGNC:5362 xref: UniGene:Hs.76884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001717 ! ID3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004850 name: IDI2_human def: "Isopentenyl-diphosphate Delta-isomerase 2 gene" [UniProtKB:Q9BXS1] xref: EMBL:AF271725 xref: EMBL:AF271726 xref: EMBL:AF271727 xref: EMBL:AF271728 xref: EMBL:AF271729 xref: EMBL:AF291755 xref: EMBL:AK056950 xref: EMBL:BC017778 xref: HGNC:HGNC:23487 xref: UniGene:Hs.591325 xref: UniGene:Hs.9270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006021 ! IDI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004851 name: EIF2S2_human def: "Eukaryotic translation initiation factor 2 subunit 2 gene" [UniProtKB:P20042] synonym: "EIF2B" EXACT [UniProtKB:P20042] xref: EMBL:AL031668 xref: EMBL:BC000461 xref: EMBL:BC000934 xref: EMBL:M29536 xref: HGNC:HGNC:3266 xref: UniGene:Hs.429180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006090 ! IF2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004862 name: EIF4A1_human def: "Eukaryotic initiation factor 4A-I gene" [UniProtKB:P60842] synonym: "DDX2A" EXACT [UniProtKB:P60842] synonym: "EIF4A" EXACT [UniProtKB:P60842] xref: EMBL:BC009585 xref: EMBL:BC073752 xref: EMBL:BT019880 xref: EMBL:BT019881 xref: EMBL:D13748 xref: HGNC:HGNC:3282 xref: UniGene:Hs.129673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005679 ! IF4A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004863 name: EIF4A2_human def: "Eukaryotic initiation factor 4A-II gene" [UniProtKB:Q14240] synonym: "DDX2B" EXACT [UniProtKB:Q14240] synonym: "EIF4F" EXACT [UniProtKB:Q14240] xref: EMBL:BC012547 xref: EMBL:BC013708 xref: EMBL:BC015842 xref: EMBL:BC048105 xref: EMBL:D30655 xref: HGNC:HGNC:3284 xref: UniGene:Hs.599481 xref: UniGene:Hs.700566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005728 ! IF4A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004864 name: EIF4G2_human def: "Eukaryotic translation initiation factor 4 gamma 2 gene" [UniProtKB:P78344] synonym: "DAP5" EXACT [UniProtKB:P78344] synonym: "OK/SW-cl.75" EXACT [UniProtKB:P78344] xref: EMBL:AB063323 xref: EMBL:AK223548 xref: EMBL:BC014930 xref: EMBL:BC018975 xref: EMBL:BC039851 xref: EMBL:BC111415 xref: EMBL:U73824 xref: EMBL:U76111 xref: EMBL:X89713 xref: HGNC:HGNC:3297 xref: UniGene:Hs.183684 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001699 ! IF4G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004865 name: IFITM1_human def: "Interferon-induced transmembrane protein 1 gene" [UniProtKB:P13164] synonym: "CD225" EXACT [UniProtKB:P13164] synonym: "IFI17" EXACT [UniProtKB:P13164] xref: EMBL:AC136475 xref: EMBL:BC000897 xref: EMBL:J04164 xref: EMBL:X84958 xref: HGNC:HGNC:5412 xref: UniGene:Hs.458414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001517 ! IFM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004866 name: IFNW1_human def: "Interferon omega-1 precursor gene" [UniProtKB:P05000] xref: EMBL:A12140 xref: EMBL:AL390882 xref: EMBL:AY780805 xref: EMBL:BC069095 xref: EMBL:BC117290 xref: EMBL:BC117292 xref: EMBL:CH471071 xref: EMBL:M11003 xref: EMBL:U25670 xref: EMBL:X02669 xref: EMBL:X58822 xref: HGNC:HGNC:5448 xref: UniGene:Hs.73010 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001484 ! IFNW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004867 name: IGF1R_human def: "Insulin-like growth factor 1 receptor precursor gene" [UniProtKB:P08069] xref: EMBL:AY332722 xref: EMBL:BC113610 xref: EMBL:BC113612 xref: EMBL:M69229 xref: EMBL:X04434 xref: HGNC:HGNC:5465 xref: UniGene:Hs.643120 xref: UniGene:Hs.653608 xref: UniGene:Hs.698330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001497 ! IGF1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004868 name: IGF2_human def: "Insulin-like growth factor II precursor gene" [UniProtKB:P01344] synonym: "PP1446" EXACT [UniProtKB:P01344] xref: EMBL:AF217977 xref: EMBL:AF517226 xref: EMBL:BC000531 xref: EMBL:BT007013 xref: EMBL:DQ104203 xref: EMBL:J03242 xref: EMBL:M17426 xref: EMBL:M17863 xref: EMBL:M22373 xref: EMBL:M29645 xref: EMBL:S77035 xref: EMBL:X00910 xref: EMBL:X03425 xref: EMBL:X03426 xref: EMBL:X03427 xref: EMBL:X03562 xref: EMBL:X06159 xref: EMBL:X06160 xref: EMBL:X06161 xref: EMBL:X07868 xref: HGNC:HGNC:5466 xref: UniGene:Hs.523414 xref: UniGene:Hs.654579 xref: UniGene:Hs.700350 xref: UniGene:Hs.700789 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001472 ! IGF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004869 name: IGHA1_human def: "Ig alpha-1 chain C region gene" [UniProtKB:P01876] xref: EMBL:J00220 xref: HGNC:HGNC:5478 xref: UniGene:Hs.648398 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005921 ! IGHA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004870 name: IGSF21_human def: "Immunoglobulin superfamily member 21 precursor gene" [UniProtKB:Q96ID5] xref: EMBL:AK075316 xref: EMBL:AL050342 xref: EMBL:AL356101 xref: EMBL:AL359738 xref: EMBL:AL365209 xref: EMBL:BC007618 xref: HGNC:HGNC:28246 xref: UniGene:Hs.212511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006168 ! IGS21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004871 name: NFKBIA_human def: "NF-kappa-B inhibitor alpha gene" [UniProtKB:P25963] synonym: "IKBA" EXACT [UniProtKB:P25963] synonym: "MAD3" EXACT [UniProtKB:P25963] synonym: "NFKBI" EXACT [UniProtKB:P25963] xref: EMBL:AJ249283 xref: EMBL:AJ249284 xref: EMBL:AJ249285 xref: EMBL:AJ249286 xref: EMBL:AJ249294 xref: EMBL:AJ249295 xref: EMBL:AY033600 xref: EMBL:AY496422 xref: EMBL:BC002601 xref: EMBL:BC004983 xref: EMBL:BT007091 xref: EMBL:M69043 xref: HGNC:HGNC:7797 xref: UniGene:Hs.81328 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005521 ! IKBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004872 name: NFKBIB_human def: "NF-kappa-B inhibitor beta gene" [UniProtKB:Q15653] synonym: "IKBB" EXACT [UniProtKB:Q15653] synonym: "TRIP9" EXACT [UniProtKB:Q15653] xref: EMBL:AY736284 xref: EMBL:BC007197 xref: EMBL:BC015528 xref: EMBL:BT006743 xref: EMBL:L40407 xref: HGNC:HGNC:7798 xref: UniGene:Hs.9731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005537 ! IKBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004873 name: NFKBIE_human def: "NF-kappa-B inhibitor epsilon gene" [UniProtKB:O00221] synonym: "IKBE" EXACT [UniProtKB:O00221] xref: EMBL:AL139392 xref: EMBL:CH471081 xref: EMBL:U91616 xref: HGNC:HGNC:7799 xref: UniGene:Hs.458276 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005538 ! IKBE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004874 name: CHUK_human def: "Inhibitor of nuclear factor kappa-B kinase subunit alpha gene" [UniProtKB:O15111] synonym: "IKKA" EXACT [UniProtKB:O15111] synonym: "TCF16" EXACT [UniProtKB:O15111] xref: EMBL:AF009225 xref: EMBL:AF012890 xref: EMBL:AF080157 xref: EMBL:AL138921 xref: EMBL:AY652653 xref: EMBL:U22512 xref: HGNC:HGNC:1974 xref: UniGene:Hs.198998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005539 ! IKKA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004875 name: IKBKB_human def: "Inhibitor of nuclear factor kappa-B kinase subunit beta gene" [UniProtKB:O14920] synonym: "IKKB" EXACT [UniProtKB:O14920] xref: EMBL:AF029684 xref: EMBL:AF031416 xref: EMBL:AF080158 xref: EMBL:AY663108 xref: EMBL:BC006231 xref: HGNC:HGNC:5960 xref: UniGene:Hs.656458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005522 ! IKKB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004876 name: IKBKE_human def: "Inhibitor of nuclear factor kappa-B kinase subunit epsilon gene" [UniProtKB:Q14164] synonym: "IKKE" EXACT [UniProtKB:Q14164] synonym: "IKKI" EXACT [UniProtKB:Q14164] synonym: "KIAA0151" EXACT [UniProtKB:Q14164] xref: EMBL:AB016590 xref: EMBL:AF241789 xref: EMBL:AL354681 xref: EMBL:BC105923 xref: EMBL:BC105924 xref: EMBL:D63485 xref: EMBL:DQ667176 xref: HGNC:HGNC:14552 xref: UniGene:Hs.321045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005523 ! IKKE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004877 name: IKZF1_human def: "DNA-binding protein Ikaros gene" [UniProtKB:Q13422] synonym: "IK1" EXACT [UniProtKB:Q13422] synonym: "IKAROS" EXACT [UniProtKB:Q13422] synonym: "LYF1" EXACT [UniProtKB:Q13422] synonym: "ZNFN1A1" EXACT [UniProtKB:Q13422] xref: EMBL:BC018349 xref: EMBL:S80876 xref: EMBL:U40462 xref: HGNC:HGNC:13176 xref: UniGene:Hs.435949 xref: UniGene:Hs.488251 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005213 ! IKZF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004878 name: IL1A_human def: "Interleukin-1 alpha precursor gene" [UniProtKB:P01583] synonym: "IL1F1" EXACT [UniProtKB:P01583] xref: EMBL:AF536338 xref: EMBL:BC013142 xref: EMBL:BN000002 xref: EMBL:BT007014 xref: EMBL:CR457414 xref: EMBL:M15329 xref: EMBL:M28983 xref: EMBL:X02531 xref: EMBL:X02851 xref: EMBL:X03833 xref: EMBL:X56086 xref: HGNC:HGNC:5991 xref: UniGene:Hs.1722 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001475 ! IL1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004879 name: IL1B_human def: "Interleukin-1 beta precursor gene" [UniProtKB:P01584] synonym: "IL1F2" EXACT [UniProtKB:P01584] xref: EMBL:AC079753 xref: EMBL:AY137079 xref: EMBL:BC008678 xref: EMBL:BN000002 xref: EMBL:BT007213 xref: EMBL:CH471217 xref: EMBL:CR407679 xref: EMBL:K02770 xref: EMBL:M15330 xref: EMBL:M15840 xref: EMBL:M54933 xref: EMBL:X02532 xref: EMBL:X04500 xref: EMBL:X56087 xref: HGNC:HGNC:5992 xref: UniGene:Hs.126256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001476 ! IL1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004880 name: IL1F5_human def: "Interleukin-1 family member 5 gene" [UniProtKB:Q9UBH0] synonym: "FIL1D" EXACT [UniProtKB:Q9UBH0] synonym: "IL1HY1" EXACT [UniProtKB:Q9UBH0] synonym: "IL1L1" EXACT [UniProtKB:Q9UBH0] synonym: "IL1RP3" EXACT [UniProtKB:Q9UBH0] synonym: "UNQ1896/PRO4342" EXACT [UniProtKB:Q9UBH0] xref: EMBL:AC016724 xref: EMBL:AF186094 xref: EMBL:AF201830 xref: EMBL:AF216693 xref: EMBL:AF230377 xref: EMBL:AJ242737 xref: EMBL:AJ242738 xref: EMBL:AJ271338 xref: EMBL:AY359117 xref: EMBL:AY972853 xref: EMBL:BC024747 xref: EMBL:BN000002 xref: HGNC:HGNC:15561 xref: UniGene:Hs.516301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005205 ! IL1F5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004881 name: IL1R1_human def: "Interleukin-1 receptor type I precursor gene" [UniProtKB:P14778] synonym: "IL1R" EXACT [UniProtKB:P14778] synonym: "IL1RA" EXACT [UniProtKB:P14778] synonym: "IL1RT1" EXACT [UniProtKB:P14778] xref: EMBL:AF531102 xref: EMBL:BC067506 xref: EMBL:BC075062 xref: EMBL:BC075063 xref: EMBL:M27492 xref: EMBL:X16896 xref: HGNC:HGNC:5993 xref: UniGene:Hs.701982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005325 ! IL1R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004882 name: IL2RA_human def: "Interleukin-2 receptor alpha chain precursor gene" [UniProtKB:P01589] xref: EMBL:AY563103 xref: EMBL:K03122 xref: EMBL:M10322 xref: EMBL:M11060 xref: EMBL:M11061 xref: EMBL:M11062 xref: EMBL:M11063 xref: EMBL:M11064 xref: EMBL:M11065 xref: EMBL:M11066 xref: EMBL:M15864 xref: EMBL:X01057 xref: EMBL:X03131 xref: EMBL:X03132 xref: EMBL:X03133 xref: EMBL:X03134 xref: EMBL:X03135 xref: EMBL:X03136 xref: EMBL:X03137 xref: EMBL:X03138 xref: HGNC:HGNC:6008 xref: UniGene:Hs.231367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001477 ! IL2RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004883 name: IL8_human def: "Interleukin-8 precursor gene" [UniProtKB:P10145] synonym: "CXCL8" EXACT [UniProtKB:P10145] xref: EMBL:AF043337 xref: EMBL:AF385628 xref: EMBL:AK311874 xref: EMBL:BC013615 xref: EMBL:BT007067 xref: EMBL:CH471057 xref: EMBL:CR542151 xref: EMBL:D14283 xref: EMBL:M17017 xref: EMBL:M26383 xref: EMBL:M28130 xref: EMBL:Y00787 xref: EMBL:Z11686 xref: HGNC:HGNC:6025 xref: UniGene:Hs.551925 xref: UniGene:Hs.561078 xref: UniGene:Hs.624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001504 ! IL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004884 name: ILF3_human def: "Interleukin enhancer-binding factor 3 gene" [UniProtKB:Q12906] synonym: "DRBF" EXACT [UniProtKB:Q12906] synonym: "MPHOSPH4" EXACT [UniProtKB:Q12906] synonym: "NF90" EXACT [UniProtKB:Q12906] xref: EMBL:AF007140 xref: EMBL:AF141870 xref: EMBL:AF147209 xref: EMBL:AF167569 xref: EMBL:AF167570 xref: EMBL:AF202445 xref: EMBL:AF320228 xref: EMBL:AF320229 xref: EMBL:AF320230 xref: EMBL:AF320231 xref: EMBL:AF320232 xref: EMBL:AF320233 xref: EMBL:AF320234 xref: EMBL:AF320235 xref: EMBL:AF320236 xref: EMBL:AF320237 xref: EMBL:AF320238 xref: EMBL:AF320239 xref: EMBL:AF320240 xref: EMBL:AF320241 xref: EMBL:AF320242 xref: EMBL:AF320243 xref: EMBL:AF320244 xref: EMBL:AF320245 xref: EMBL:AF320246 xref: EMBL:AF320247 xref: EMBL:AJ271741 xref: EMBL:AJ271744 xref: EMBL:AJ271745 xref: EMBL:AJ271746 xref: EMBL:AJ271747 xref: EMBL:AK000018 xref: EMBL:AK025821 xref: EMBL:BC003086 xref: EMBL:BC048314 xref: EMBL:BC064836 xref: EMBL:CR457223 xref: EMBL:U10324 xref: EMBL:X98264 xref: EMBL:X98265 xref: HGNC:HGNC:6038 xref: UniGene:Hs.465885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001734 ! ILF3_HUMAN relationship: codes_for CCO:B0062833 ! Q9NXX0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004885 name: ILKAP_human def: "Integrin-linked kinase-associated serine/threonine phosphatase 2C gene" [UniProtKB:Q9H0C8] xref: EMBL:AC016757 xref: EMBL:AL136850 xref: EMBL:AY024365 xref: EMBL:BC006576 xref: EMBL:CR533533 xref: HGNC:HGNC:15566 xref: UniGene:Hs.92033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002123 ! ILKAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004886 name: KPNA2_human def: "Importin subunit alpha-2 gene" [UniProtKB:P52292] synonym: "RCH1" EXACT [UniProtKB:P52292] synonym: "SRP1" EXACT [UniProtKB:P52292] xref: EMBL:AJ303086 xref: EMBL:BC005978 xref: EMBL:U09559 xref: EMBL:U28386 xref: HGNC:HGNC:6395 xref: UniGene:Hs.594238 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001657 ! IMA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004887 name: KPNA3_human def: "Importin subunit alpha-3 gene" [UniProtKB:O00505] synonym: "QIP2" EXACT [UniProtKB:O00505] xref: EMBL:AF034756 xref: EMBL:BC017355 xref: EMBL:BC024202 xref: EMBL:D89618 xref: EMBL:Y12394 xref: HGNC:HGNC:6396 xref: UniGene:Hs.527919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005931 ! IMA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004888 name: KPNA5_human def: "Importin subunit alpha-6 gene" [UniProtKB:O15131] xref: EMBL:AF005361 xref: EMBL:AL132795 xref: EMBL:BC047409 xref: HGNC:HGNC:6398 xref: UniGene:Hs.182971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005697 ! IMA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004889 name: KPNB1_human def: "Importin subunit beta-1 gene" [UniProtKB:Q14974] synonym: "NTF97" EXACT [UniProtKB:Q14974] xref: EMBL:BC003572 xref: EMBL:BC024045 xref: EMBL:BC036703 xref: EMBL:L38951 xref: EMBL:L39793 xref: HGNC:HGNC:6400 xref: UniGene:Hs.532793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005409 ! IMB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004890 name: IMMT_human def: "Mitochondrial inner membrane protein gene" [UniProtKB:Q16891] synonym: "HMP" EXACT [UniProtKB:Q16891] synonym: "PIG4" EXACT [UniProtKB:Q16891] xref: EMBL:AF148646 xref: EMBL:AY232292 xref: EMBL:BC002412 xref: EMBL:BC027458 xref: EMBL:BX537369 xref: EMBL:CR456793 xref: EMBL:CR749590 xref: EMBL:D21091 xref: EMBL:D21092 xref: EMBL:D21093 xref: EMBL:D21094 xref: EMBL:L42572 xref: HGNC:HGNC:6047 xref: UniGene:Hs.148559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006201 ! IMMT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004891 name: INCENP_human def: "Inner centromere protein gene" [UniProtKB:Q9NQS7] xref: EMBL:AF282265 xref: EMBL:AP002793 xref: EMBL:AY714053 xref: EMBL:BC098576 xref: EMBL:CH471076 xref: HGNC:HGNC:6058 xref: UniGene:Hs.142179 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002154 ! INCE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004892 name: ING1_human def: "Inhibitor of growth protein 1 gene" [UniProtKB:Q9UK53] xref: EMBL:AB024401 xref: EMBL:AB024402 xref: EMBL:AB024403 xref: EMBL:AB024404 xref: EMBL:AB024405 xref: EMBL:AB031269 xref: EMBL:AB037387 xref: EMBL:AB037594 xref: EMBL:AF001954 xref: EMBL:AF044076 xref: EMBL:AF078835 xref: EMBL:AF078836 xref: EMBL:AF078837 xref: EMBL:AF149721 xref: EMBL:AF149722 xref: EMBL:AF149723 xref: EMBL:AF167549 xref: EMBL:AF167550 xref: EMBL:AF167551 xref: EMBL:AF181849 xref: EMBL:AF181850 xref: EMBL:AJ310392 xref: EMBL:AL157820 xref: HGNC:HGNC:6062 xref: UniGene:Hs.46700 xref: UniGene:Hs.508725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002217 ! ING1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004893 name: ING3_human def: "Inhibitor of growth protein 3 gene" [UniProtKB:Q9NXR8] synonym: "HSPC301" EXACT [UniProtKB:Q9NXR8] xref: EMBL:AC004537 xref: EMBL:AF074968 xref: EMBL:AF161419 xref: EMBL:AK000096 xref: EMBL:AL603623 xref: EMBL:AY007790 xref: EMBL:BC009777 xref: EMBL:BC010851 xref: EMBL:BC062634 xref: EMBL:BC073865 xref: HGNC:HGNC:14587 xref: UniGene:Hs.489811 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005368 ! ING3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004894 name: ING4_human def: "Inhibitor of growth protein 4 gene" [UniProtKB:Q9UNL4] synonym: "My036" EXACT [UniProtKB:Q9UNL4] xref: EMBL:AF063594 xref: EMBL:AF110645 xref: EMBL:AF156552 xref: EMBL:BC007781 xref: EMBL:BC013038 xref: HGNC:HGNC:19423 xref: UniGene:Hs.524210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002234 ! ING4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004895 name: ING5_human def: "Inhibitor of growth protein 5 gene" [UniProtKB:Q8WYH8] xref: EMBL:AF189286 xref: EMBL:AK074422 xref: EMBL:BC005370 xref: EMBL:BC071899 xref: HGNC:HGNC:19421 xref: UniGene:Hs.529172 xref: UniGene:Hs.645460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005284 ! ING5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004896 name: INHA_human def: "Inhibin alpha chain precursor gene" [UniProtKB:P05111] xref: EMBL:BC006391 xref: EMBL:BT006954 xref: EMBL:M13144 xref: EMBL:M13981 xref: EMBL:X04445 xref: EMBL:X04446 xref: HGNC:HGNC:6065 xref: UniGene:Hs.407506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001485 ! INHA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004897 name: INHBA_human def: "Inhibin beta A chain precursor gene" [UniProtKB:P08476] xref: EMBL:AC005027 xref: EMBL:BC007858 xref: EMBL:J03634 xref: EMBL:M13436 xref: EMBL:X04447 xref: EMBL:X57578 xref: EMBL:X57579 xref: EMBL:X72498 xref: HGNC:HGNC:6066 xref: UniGene:Hs.583348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001498 ! INHBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004899 name: INPP1_human def: "Inositol polyphosphate 1-phosphatase gene" [UniProtKB:P49441] xref: EMBL:AF141325 xref: EMBL:BC015496 xref: EMBL:L08488 xref: HGNC:HGNC:6071 xref: UniGene:Hs.32309 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006332 ! INPP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004900 name: INSR_human def: "Insulin receptor precursor gene" [UniProtKB:P06213] xref: EMBL:BC117172 xref: EMBL:J03466 xref: EMBL:J05043 xref: EMBL:M10051 xref: EMBL:M23100 xref: EMBL:M24555 xref: EMBL:M27195 xref: EMBL:M27197 xref: EMBL:M29929 xref: EMBL:M29930 xref: EMBL:M32823 xref: EMBL:M32824 xref: EMBL:M32825 xref: EMBL:M32826 xref: EMBL:M32827 xref: EMBL:M32828 xref: EMBL:M32829 xref: EMBL:M32830 xref: EMBL:M32831 xref: EMBL:M32832 xref: EMBL:M32833 xref: EMBL:M32834 xref: EMBL:M32835 xref: EMBL:M32836 xref: EMBL:M32837 xref: EMBL:M32838 xref: EMBL:M32839 xref: EMBL:M32840 xref: EMBL:M32841 xref: EMBL:M32842 xref: EMBL:M32972 xref: EMBL:M76592 xref: EMBL:X02160 xref: HGNC:HGNC:6091 xref: UniGene:Hs.465744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005478 ! INSR_HUMAN relationship: codes_for CCO:B0029064 ! Q17RW0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004901 name: IPO7_human def: "Importin-7 gene" [UniProtKB:O95373] synonym: "RANBP7" EXACT [UniProtKB:O95373] xref: EMBL:AC055845 xref: EMBL:AF098799 xref: EMBL:AJ295844 xref: EMBL:AL137335 xref: EMBL:BC114929 xref: EMBL:CH471064 xref: HGNC:HGNC:9852 xref: UniGene:Hs.699345 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005661 ! IPO7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004902 name: PPA1_human def: "Inorganic pyrophosphatase gene" [UniProtKB:Q15181] synonym: "IOPPP" EXACT [UniProtKB:Q15181] synonym: "PP" EXACT [UniProtKB:Q15181] xref: EMBL:AB026723 xref: EMBL:AF092439 xref: EMBL:AF108211 xref: EMBL:AF119665 xref: EMBL:AF154065 xref: EMBL:AF217186 xref: EMBL:AL731540 xref: EMBL:BC001022 xref: EMBL:BC061581 xref: EMBL:BC105034 xref: EMBL:BC105036 xref: EMBL:BC107882 xref: EMBL:Z48605 xref: HGNC:HGNC:9226 xref: UniGene:Hs.437403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006102 ! IPYR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004903 name: IRF1_human def: "Interferon regulatory factor 1 gene" [UniProtKB:P10914] xref: EMBL:AB103081 xref: EMBL:BC009483 xref: EMBL:BT019756 xref: EMBL:L05072 xref: EMBL:X14454 xref: HGNC:HGNC:6116 xref: UniGene:Hs.436061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001510 ! IRF1_HUMAN relationship: codes_for CCO:B0019239 ! Q5FBX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004904 name: ITGAE_human def: "Integrin alpha-E precursor gene" [UniProtKB:P38570] xref: EMBL:AC116914 xref: EMBL:AF168787 xref: EMBL:BC113436 xref: EMBL:BC117207 xref: EMBL:L25851 xref: HGNC:HGNC:6147 xref: UniGene:Hs.513867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006318 ! ITAE_HUMAN relationship: codes_for CCO:B0050198 ! A8MTX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004905 name: TCF4_human def: "Transcription factor 4 gene" [UniProtKB:P15884] synonym: "ITF2" EXACT [UniProtKB:P15884] synonym: "SEF2" EXACT [UniProtKB:P15884] xref: EMBL:AV761952 xref: EMBL:BC125084 xref: EMBL:BC125085 xref: EMBL:M74718 xref: EMBL:M74719 xref: EMBL:M74720 xref: EMBL:U75701 xref: EMBL:X52079 xref: HGNC:HGNC:11634 xref: UniGene:Hs.644653 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005715 ! ITF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004906 name: ITSN2_human def: "Intersectin-2 gene" [UniProtKB:Q9NZM3] synonym: "KIAA1256" EXACT [UniProtKB:Q9NZM3] synonym: "SH3D1B" EXACT [UniProtKB:Q9NZM3] synonym: "SWAP" EXACT [UniProtKB:Q9NZM3] xref: EMBL:AB033082 xref: EMBL:AF001630 xref: EMBL:AF182198 xref: EMBL:AF182199 xref: EMBL:AF248540 xref: EMBL:AK000302 xref: EMBL:AK021545 xref: EMBL:U61167 xref: HGNC:HGNC:6184 xref: UniGene:Hs.432562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006199 ! ITSN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004907 name: JAG2_human def: "Protein jagged-2 precursor gene" [UniProtKB:Q9Y219] xref: EMBL:AF003521 xref: EMBL:AF020201 xref: EMBL:AF029778 xref: EMBL:AF029779 xref: EMBL:AF111170 xref: EMBL:Y14330 xref: HGNC:HGNC:6189 xref: UniGene:Hs.433445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002245 ! JAG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004908 name: JAK2_human def: "Tyrosine-protein kinase JAK2 gene" [UniProtKB:O60674] xref: EMBL:AF001362 xref: EMBL:AF005216 xref: EMBL:AF058925 xref: EMBL:AL161450 xref: HGNC:HGNC:6192 xref: UniGene:Hs.656213 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001414 ! JAK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004909 name: JAK3_human def: "Tyrosine-protein kinase JAK3 gene" [UniProtKB:P52333] xref: EMBL:AC007201 xref: EMBL:AF513860 xref: EMBL:U09607 xref: EMBL:U31601 xref: EMBL:U31602 xref: EMBL:U57096 xref: HGNC:HGNC:6193 xref: UniGene:Hs.515247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005612 ! JAK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004910 name: FBXL11_human def: "JmjC domain-containing histone demethylation protein 1A gene" [UniProtKB:Q9Y2K7] synonym: "CXXC8" EXACT [UniProtKB:Q9Y2K7] synonym: "FBL7" EXACT [UniProtKB:Q9Y2K7] synonym: "JHDM1A" EXACT [UniProtKB:Q9Y2K7] synonym: "KIAA1004" EXACT [UniProtKB:Q9Y2K7] xref: EMBL:AB023221 xref: EMBL:AF179221 xref: EMBL:AK024505 xref: EMBL:AL117517 xref: EMBL:BC001203 xref: EMBL:BC047371 xref: EMBL:BC047486 xref: EMBL:BC064360 xref: HGNC:HGNC:13606 xref: UniGene:Hs.124147 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006051 ! JHD1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004911 name: MAPK8IP3_human def: "C-jun-amino-terminal kinase-interacting protein 3 gene" [UniProtKB:Q9UPT6] synonym: "JIP3" EXACT [UniProtKB:Q9UPT6] synonym: "KIAA1066" EXACT [UniProtKB:Q9UPT6] xref: EMBL:AB028989 xref: EMBL:AC012180 xref: EMBL:AE006639 xref: EMBL:AK024437 xref: EMBL:AL031710 xref: EMBL:AL031717 xref: EMBL:AL031718 xref: HGNC:HGNC:6884 xref: UniGene:Hs.207763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006034 ! JIP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004912 name: JUNB_human def: "Transcription factor jun-B gene" [UniProtKB:P17275] xref: EMBL:AY751746 xref: EMBL:BC004250 xref: EMBL:BC009465 xref: EMBL:BC009466 xref: EMBL:M29039 xref: EMBL:U20734 xref: EMBL:X51345 xref: HGNC:HGNC:6205 xref: UniGene:Hs.25292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001530 ! JUNB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004913 name: JUN_human def: "Transcription factor AP-1 gene" [UniProtKB:P05412] xref: EMBL:AL136985 xref: EMBL:AY217548 xref: EMBL:BC002646 xref: EMBL:BC006175 xref: EMBL:BC009874 xref: EMBL:BC068522 xref: EMBL:BT019759 xref: EMBL:J04111 xref: HGNC:HGNC:6204 xref: UniGene:Hs.525704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001487 ! JUN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004914 name: KIAA0087_human def: "Uncharacterized protein KIAA0087 gene" [UniProtKB:Q14695] synonym: "HA1002" EXACT [UniProtKB:Q14695] xref: EMBL:AC004947 xref: EMBL:BC128257 xref: EMBL:CH236948 xref: EMBL:CH471073 xref: EMBL:D42038 xref: HGNC:HGNC:22191 xref: UniGene:Hs.69749 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006280 ! K0087_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004915 name: KIAA0240_human def: "Uncharacterized protein KIAA0240 gene" [UniProtKB:Q6AI39] xref: EMBL:AL035587 xref: EMBL:AL353716 xref: EMBL:CR627378 xref: EMBL:D87077 xref: HGNC:HGNC:21111 xref: UniGene:Hs.658033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005596 ! K0240_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004916 name: KIAA1267_human def: "Uncharacterized protein KIAA1267 gene" [UniProtKB:Q7Z3B3] xref: EMBL:AB033093 xref: EMBL:AL117476 xref: EMBL:AL137317 xref: EMBL:BC006271 xref: EMBL:BC035892 xref: EMBL:BC098376 xref: EMBL:BX538006 xref: EMBL:BX648760 xref: HGNC:HGNC:24565 xref: UniGene:Hs.648744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005600 ! K1267_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004917 name: KIAA1279_human def: "KIF1-binding protein gene" [UniProtKB:Q96EK5] synonym: "KBP" EXACT [UniProtKB:Q96EK5] xref: EMBL:AB033105 xref: EMBL:AK291343 xref: EMBL:AL050190 xref: EMBL:AL359844 xref: EMBL:BC012180 xref: HGNC:HGNC:23419 xref: UniGene:Hs.279580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043863 ! KBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004918 name: KIAA1377_human def: "Uncharacterized protein KIAA1377 gene" [UniProtKB:Q9P2H0] xref: EMBL:AB037798 xref: EMBL:AP003383 xref: HGNC:HGNC:29264 xref: UniGene:Hs.156352 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005403 ! K1377_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004919 name: KIAA1683_human def: "Uncharacterized protein KIAA1683 gene" [UniProtKB:Q9H0B3] xref: EMBL:AB051470 xref: EMBL:AK057466 xref: EMBL:AL136867 xref: EMBL:BC034327 xref: HGNC:HGNC:29350 xref: UniGene:Hs.313471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005254 ! K1683_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004920 name: KRT14_human def: "Keratin, type I cytoskeletal 14 gene" [UniProtKB:P02533] xref: EMBL:AF186085 xref: EMBL:AF186086 xref: EMBL:AF186087 xref: EMBL:AF186088 xref: EMBL:AF186089 xref: EMBL:AF186090 xref: EMBL:BC002690 xref: EMBL:BC019097 xref: EMBL:BC042437 xref: EMBL:BC094830 xref: EMBL:BT007186 xref: EMBL:D28807 xref: EMBL:J00124 xref: HGNC:HGNC:6416 xref: UniGene:Hs.654380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005817 ! K1C14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004921 name: KRT15_human def: "Keratin, type I cytoskeletal 15 gene" [UniProtKB:P19012] synonym: "KRTB" EXACT [UniProtKB:P19012] xref: EMBL:AC019349 xref: EMBL:AF202320 xref: EMBL:BC002641 xref: EMBL:BT007261 xref: EMBL:X07696 xref: HGNC:HGNC:6421 xref: UniGene:Hs.654570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005207 ! K1C15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004922 name: KRT17_human def: "Keratin, type I cytoskeletal 17 gene" [UniProtKB:Q04695] xref: EMBL:AC022596 xref: EMBL:AK095342 xref: EMBL:AL353997 xref: EMBL:BC000159 xref: EMBL:BC011901 xref: EMBL:BC056421 xref: EMBL:BC072018 xref: EMBL:BC072019 xref: EMBL:EF608068 xref: EMBL:EF608069 xref: EMBL:EF608070 xref: EMBL:EF608071 xref: EMBL:S78515 xref: EMBL:X62571 xref: EMBL:Z19574 xref: HGNC:HGNC:6427 xref: UniGene:Hs.2785 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005844 ! K1C17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004923 name: KRT18_human def: "Keratin, type I cytoskeletal 18 gene" [UniProtKB:P05783] synonym: "CYK18" EXACT [UniProtKB:P05783] synonym: "PIG46" EXACT [UniProtKB:P05783] xref: EMBL:AF179904 xref: EMBL:AK223093 xref: EMBL:AY762101 xref: EMBL:BC000180 xref: EMBL:BC000698 xref: EMBL:BC004253 xref: EMBL:BC008636 xref: EMBL:BC020982 xref: EMBL:BC072017 xref: EMBL:BT019412 xref: EMBL:X12876 xref: EMBL:X12881 xref: EMBL:X12883 xref: HGNC:HGNC:6430 xref: UniGene:Hs.406013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001489 ! K1C18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004924 name: KRT9_human def: "Keratin, type I cytoskeletal 9 gene" [UniProtKB:P35527] xref: EMBL:AB001594 xref: EMBL:BC121170 xref: EMBL:S69510 xref: EMBL:X75015 xref: EMBL:Z29074 xref: HGNC:HGNC:6447 xref: UniGene:Hs.654569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005922 ! K1C9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004925 name: KRT1_human def: "Keratin, type II cytoskeletal 1 gene" [UniProtKB:P04264] synonym: "KRTA" EXACT [UniProtKB:P04264] xref: EMBL:AF237621 xref: EMBL:AF304164 xref: EMBL:BC063697 xref: EMBL:M10938 xref: EMBL:M98776 xref: HGNC:HGNC:6412 xref: UniGene:Hs.80828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005823 ! K2C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004926 name: KRT5_human def: "Keratin, type II cytoskeletal 5 gene" [UniProtKB:P13647] xref: EMBL:AF274874 xref: EMBL:AY373434 xref: EMBL:BC024292 xref: EMBL:BC042132 xref: EMBL:BC071906 xref: EMBL:M19723 xref: EMBL:M21389 xref: EMBL:M28496 xref: HGNC:HGNC:6442 xref: UniGene:Hs.433845 xref: UniGene:Hs.694210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005811 ! K2C5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004927 name: KRT6A_human def: "Keratin, type II cytoskeletal 6A gene" [UniProtKB:P02538] synonym: "K6A" EXACT [UniProtKB:P02538] synonym: "KRT6D" EXACT [UniProtKB:P02538] xref: EMBL:BC008807 xref: EMBL:BC014152 xref: EMBL:BC069269 xref: EMBL:BC125058 xref: EMBL:BT006899 xref: EMBL:L42575 xref: EMBL:L42576 xref: EMBL:L42577 xref: EMBL:L42578 xref: EMBL:L42579 xref: EMBL:L42580 xref: EMBL:L42581 xref: EMBL:L42583 xref: EMBL:L42603 xref: EMBL:L42604 xref: EMBL:L42605 xref: EMBL:L42606 xref: EMBL:L42607 xref: EMBL:L42608 xref: EMBL:L42609 xref: EMBL:L42610 xref: EMBL:V01516 xref: HGNC:HGNC:6443 xref: UniGene:Hs.433845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005821 ! K2C6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004928 name: KRT7_human def: "Keratin, type II cytoskeletal 7 gene" [UniProtKB:P08729] synonym: "SCL" EXACT [UniProtKB:P08729] xref: EMBL:AF509887 xref: EMBL:AF509891 xref: EMBL:AF509892 xref: EMBL:AJ238246 xref: EMBL:BC002700 xref: EMBL:X03212 xref: EMBL:X13320 xref: EMBL:X13346 xref: EMBL:X13347 xref: EMBL:X13348 xref: EMBL:X13349 xref: EMBL:X13350 xref: EMBL:X13351 xref: EMBL:X13352 xref: EMBL:X13353 xref: HGNC:HGNC:6445 xref: UniGene:Hs.411501 xref: UniGene:Hs.670221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001501 ! K2C7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004929 name: KRT8_human def: "Keratin, type II cytoskeletal 8 gene" [UniProtKB:P05787] synonym: "CYK8" EXACT [UniProtKB:P05787] xref: EMBL:AK222941 xref: EMBL:BC000654 xref: EMBL:BC063513 xref: EMBL:BC073760 xref: EMBL:BC075839 xref: EMBL:M26512 xref: EMBL:M34225 xref: EMBL:M34482 xref: EMBL:U76549 xref: EMBL:X12882 xref: EMBL:X74929 xref: EMBL:X74981 xref: EMBL:X98614 xref: HGNC:HGNC:6446 xref: UniGene:Hs.533782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005900 ! K2C8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004930 name: PRKAR1A_human def: "cAMP-dependent protein kinase type I-alpha regulatory subunit gene" [UniProtKB:P10644] synonym: "PKR1" EXACT [UniProtKB:P10644] synonym: "PRKAR1" EXACT [UniProtKB:P10644] synonym: "TSE1" EXACT [UniProtKB:P10644] xref: EMBL:AF411298 xref: EMBL:BC036285 xref: EMBL:BC093042 xref: EMBL:M18468 xref: EMBL:M33336 xref: EMBL:S54705 xref: EMBL:S54707 xref: EMBL:S54709 xref: EMBL:S54711 xref: EMBL:Y07642 xref: HGNC:HGNC:9388 xref: UniGene:Hs.280342 xref: UniGene:Hs.659124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005298 ! KAP0_HUMAN relationship: codes_for CCO:B0058319 ! Q96P62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004931 name: KBTBD7_human def: "Kelch repeat and BTB domain-containing protein 7 gene" [UniProtKB:Q8WVZ9] xref: EMBL:AK091344 xref: EMBL:AL136782 xref: EMBL:AL354696 xref: EMBL:BC022033 xref: EMBL:CH471075 xref: HGNC:HGNC:25266 xref: UniGene:Hs.63841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005401 ! KBTB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004932 name: CSNK1E_human def: "Casein kinase I isoform epsilon gene" [UniProtKB:P49674] xref: EMBL:AB024597 xref: EMBL:AB091043 xref: EMBL:AL020993 xref: EMBL:BC006490 xref: EMBL:CR456429 xref: EMBL:L37043 xref: HGNC:HGNC:2453 xref: UniGene:Hs.474833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005272 ! KC1E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004933 name: KCTD11_human def: "BTB/POZ domain-containing protein KCTD11 gene" [UniProtKB:Q693B1] synonym: "C17orf36" EXACT [UniProtKB:Q693B1] synonym: "REN" EXACT [UniProtKB:Q693B1] xref: EMBL:AY646650 xref: EMBL:BC110598 xref: HGNC:HGNC:21302 xref: UniGene:Hs.592112 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001904 ! KCD11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004934 name: KCNRG_human def: "Putative potassium channel regulatory protein gene" [UniProtKB:Q8N5I3] synonym: "CLLD4" EXACT [UniProtKB:Q8N5I3] xref: EMBL:AL832695 xref: EMBL:AY129653 xref: EMBL:AY129654 xref: EMBL:AY169387 xref: EMBL:AY169388 xref: EMBL:AY190921 xref: EMBL:AY190922 xref: EMBL:BC032343 xref: HGNC:HGNC:18893 xref: UniGene:Hs.436922 xref: UniGene:Hs.660161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005217 ! KCNRG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004935 name: CKMT2_human def: "Creatine kinase, sarcomeric mitochondrial precursor gene" [UniProtKB:P17540] xref: EMBL:BC029140 xref: EMBL:CR450315 xref: EMBL:J05401 xref: HGNC:HGNC:1996 xref: UniGene:Hs.80691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006131 ! KCRS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004936 name: PRKG2_human def: "cGMP-dependent protein kinase 2 gene" [UniProtKB:Q13237] synonym: "PRKGR2" EXACT [UniProtKB:Q13237] xref: EMBL:D70899 xref: EMBL:X94612 xref: EMBL:Y16106 xref: EMBL:Y16107 xref: EMBL:Y16108 xref: EMBL:Y16109 xref: EMBL:Y16110 xref: EMBL:Y16111 xref: EMBL:Y16112 xref: EMBL:Y16113 xref: EMBL:Y16114 xref: EMBL:Y16115 xref: EMBL:Y16116 xref: EMBL:Y16117 xref: EMBL:Y16118 xref: EMBL:Y16119 xref: EMBL:Y16120 xref: EMBL:Y16121 xref: EMBL:Y16122 xref: EMBL:Y16123 xref: HGNC:HGNC:9416 xref: UniGene:Hs.570833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001747 ! KGP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004937 name: KHDRBS1_human def: "KH domain-containing, RNA-binding, signal transduction-associated protein 1 gene" [UniProtKB:Q07666] synonym: "SAM68" EXACT [UniProtKB:Q07666] xref: EMBL:AK091346 xref: EMBL:AL139249 xref: EMBL:AL445248 xref: EMBL:BC000717 xref: EMBL:BC010132 xref: EMBL:BC019109 xref: EMBL:M88108 xref: EMBL:U78971 xref: HGNC:HGNC:18116 xref: UniGene:Hs.445893 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001722 ! KHDR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004938 name: KHDRBS3_human def: "KH domain-containing, RNA-binding, signal transduction-associated protein 3 gene" [UniProtKB:O75525] synonym: "SALP" EXACT [UniProtKB:O75525] synonym: "SLM2" EXACT [UniProtKB:O75525] xref: EMBL:AF051321 xref: EMBL:AF051322 xref: EMBL:AF069681 xref: EMBL:BC032606 xref: EMBL:BC068536 xref: HGNC:HGNC:18117 xref: UniGene:Hs.444558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005275 ! KHDR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004939 name: KIF13B_human def: "Kinesin-like protein KIF13B gene" [UniProtKB:Q9NQT8] synonym: "GAKIN" EXACT [UniProtKB:Q9NQT8] synonym: "KIAA0639" EXACT [UniProtKB:Q9NQT8] xref: EMBL:AB014539 xref: EMBL:AF279865 xref: EMBL:AL583912 xref: HGNC:HGNC:14405 xref: UniGene:Hs.444767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005849 ! KI13B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004940 name: MKI67_human def: "Antigen KI-67 gene" [UniProtKB:P46013] xref: EMBL:AL355529 xref: EMBL:AL390236 xref: EMBL:X65550 xref: EMBL:X65551 xref: EMBL:X94762 xref: HGNC:HGNC:7107 xref: UniGene:Hs.80976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001622 ! KI67_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004941 name: KIF11_human def: "Kinesin-like protein KIF11 gene" [UniProtKB:P52732] synonym: "EG5" EXACT [UniProtKB:P52732] synonym: "KNSL1" EXACT [UniProtKB:P52732] synonym: "TRIP5" EXACT [UniProtKB:P52732] xref: EMBL:AL356128 xref: EMBL:AL360222 xref: EMBL:BC126211 xref: EMBL:L40372 xref: EMBL:U37426 xref: EMBL:X85137 xref: HGNC:HGNC:6388 xref: UniGene:Hs.8878 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001659 ! KIF11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004942 name: KIF17_human def: "Kinesin-like protein KIF17 gene" [UniProtKB:Q9P2E2] synonym: "KIAA1405" EXACT [UniProtKB:Q9P2E2] synonym: "KIF3X" EXACT [UniProtKB:Q9P2E2] xref: EMBL:AB037826 xref: EMBL:AF009624 xref: EMBL:AL391357 xref: EMBL:AL663074 xref: EMBL:AY484427 xref: EMBL:BC036871 xref: EMBL:BC065927 xref: HGNC:HGNC:19167 xref: UniGene:Hs.130411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005966 ! KIF17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004943 name: KIF22_human def: "Kinesin-like protein KIF22 gene" [UniProtKB:Q14807] synonym: "KID" EXACT [UniProtKB:Q14807] synonym: "KNSL4" EXACT [UniProtKB:Q14807] xref: EMBL:AB017335 xref: EMBL:AB017430 xref: EMBL:AC002301 xref: EMBL:AK223431 xref: EMBL:AK312234 xref: EMBL:BC004352 xref: EMBL:BC028155 xref: EMBL:BT007259 xref: EMBL:CH471238 xref: HGNC:HGNC:6391 xref: UniGene:Hs.612151 xref: UniGene:Hs.613351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001792 ! KIF22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004944 name: KIF23_human def: "Kinesin-like protein KIF23 gene" [UniProtKB:Q02241] synonym: "KNSL5" EXACT [UniProtKB:Q02241] synonym: "MKLP1" EXACT [UniProtKB:Q02241] xref: EMBL:BC017705 xref: EMBL:BC051826 xref: EMBL:X67155 xref: HGNC:HGNC:6392 xref: UniGene:Hs.270845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001716 ! KIF23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004945 name: KIF25_human def: "Kinesin-like protein KIF25 gene" [UniProtKB:Q9UIL4] synonym: "KNSL3" EXACT [UniProtKB:Q9UIL4] xref: EMBL:AB012722 xref: EMBL:AB012723 xref: EMBL:AL589733 xref: HGNC:HGNC:6390 xref: UniGene:Hs.150013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002208 ! KIF25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004946 name: KIF2B_human def: "Kinesin-like protein KIF2B gene" [UniProtKB:Q8N4N8] xref: EMBL:AF333335 xref: EMBL:AK057272 xref: EMBL:BC033802 xref: HGNC:HGNC:29443 xref: UniGene:Hs.226805 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001963 ! KIF2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004947 name: KIF2C_human def: "Kinesin-like protein KIF2C gene" [UniProtKB:Q99661] synonym: "KNSL6" EXACT [UniProtKB:Q99661] xref: EMBL:AY026505 xref: EMBL:BC008764 xref: EMBL:BC014924 xref: EMBL:U63743 xref: HGNC:HGNC:6393 xref: UniGene:Hs.69360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002080 ! KIF2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004948 name: KIF3A_human def: "Kinesin-like protein KIF3A gene" [UniProtKB:Q9Y496] synonym: "KIF3" EXACT [UniProtKB:Q9Y496] xref: EMBL:AB209780 xref: EMBL:AC004237 xref: EMBL:AF041853 xref: EMBL:BC045542 xref: HGNC:HGNC:6319 xref: UniGene:Hs.43670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005880 ! KIF3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004949 name: KIF3C_human def: "Kinesin-like protein KIF3C gene" [UniProtKB:O14782] xref: EMBL:AF018164 xref: EMBL:AF035621 xref: EMBL:AJ002223 xref: EMBL:AJ002224 xref: EMBL:AJ002225 xref: EMBL:AJ002226 xref: EMBL:AJ002227 xref: EMBL:AJ002228 xref: EMBL:AJ002229 xref: EMBL:BC092406 xref: EMBL:BC130423 xref: HGNC:HGNC:6321 xref: UniGene:Hs.21611 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005598 ! KIF3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004950 name: KIF5A_human def: "Kinesin heavy chain isoform 5A gene" [UniProtKB:Q12840] synonym: "NKHC1" EXACT [UniProtKB:Q12840] xref: EMBL:AB210045 xref: EMBL:U06698 xref: HGNC:HGNC:6323 xref: UniGene:Hs.151219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006166 ! KIF5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004951 name: KIFC1_human def: "Kinesin-like protein KIFC1 gene" [UniProtKB:Q9BW19] synonym: "HSET" EXACT [UniProtKB:Q9BW19] synonym: "KNSL2" EXACT [UniProtKB:Q9BW19] xref: EMBL:AJ010479 xref: EMBL:AL021366 xref: EMBL:AL050332 xref: EMBL:AL662799 xref: EMBL:BC000712 xref: EMBL:BC063567 xref: EMBL:BC073878 xref: EMBL:BC098438 xref: EMBL:BC121041 xref: EMBL:BC121042 xref: EMBL:BX088650 xref: EMBL:BX248088 xref: EMBL:D14678 xref: HGNC:HGNC:6389 xref: UniGene:Hs.436912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002105 ! KIFC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004952 name: KIF5B_human def: "Kinesin-1 heavy chain gene" [UniProtKB:P33176] synonym: "KNS" EXACT [UniProtKB:P33176] synonym: "KNS1" EXACT [UniProtKB:P33176] xref: EMBL:AL161932 xref: EMBL:BC126279 xref: EMBL:BC126281 xref: EMBL:X65873 xref: HGNC:HGNC:6324 xref: UniGene:Hs.644646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005599 ! KINH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004953 name: TK1_human def: "Thymidine kinase, cytosolic gene" [UniProtKB:P04183] xref: EMBL:BC006484 xref: EMBL:BC007872 xref: EMBL:BC007986 xref: EMBL:BT006941 xref: EMBL:K02581 xref: EMBL:M13643 xref: EMBL:M15205 xref: HGNC:HGNC:11830 xref: UniGene:Hs.515122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006114 ! KITH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004954 name: KLK10_human def: "Kallikrein-10 precursor gene" [UniProtKB:O43240] synonym: "NES1" EXACT [UniProtKB:O43240] synonym: "PRSSL1" EXACT [UniProtKB:O43240] xref: EMBL:AC011473 xref: EMBL:AF024605 xref: EMBL:AF055481 xref: EMBL:AF243527 xref: EMBL:AY561635 xref: EMBL:BC002710 xref: HGNC:HGNC:6358 xref: UniGene:Hs.275464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001383 ! KLK10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004955 name: KNTC1_human def: "Kinetochore-associated protein 1 gene" [UniProtKB:P50748] synonym: "KIAA0166" EXACT [UniProtKB:P50748] xref: EMBL:D79988 xref: HGNC:HGNC:17255 xref: UniGene:Hs.300559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001645 ! KNTC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004957 name: PRKCA_human def: "Protein kinase C alpha type gene" [UniProtKB:P17252] synonym: "PKCA" EXACT [UniProtKB:P17252] synonym: "PRKACA" EXACT [UniProtKB:P17252] xref: EMBL:AF395829 xref: EMBL:BC053321 xref: EMBL:BC109273 xref: EMBL:BC109274 xref: EMBL:EU332865 xref: EMBL:M22199 xref: EMBL:X52479 xref: HGNC:HGNC:9393 xref: UniGene:Hs.531704 xref: UniGene:Hs.680598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001529 ! KPCA_HUMAN relationship: codes_for CCO:B0025052 ! Q7Z727_HUMAN relationship: codes_for CCO:B0054164 ! B0LPH5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004958 name: PRKCI_human def: "Protein kinase C iota type gene" [UniProtKB:P41743] synonym: "DXS1179E" EXACT [UniProtKB:P41743] xref: EMBL:BC022016 xref: EMBL:L18964 xref: EMBL:L33881 xref: HGNC:HGNC:9404 xref: UniGene:Hs.478199 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005173 ! KPCI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004959 name: PRKCZ_human def: "Protein kinase C zeta type gene" [UniProtKB:Q05513] synonym: "PKC2" EXACT [UniProtKB:Q05513] xref: EMBL:AL391845 xref: EMBL:AL590822 xref: EMBL:AL645703 xref: EMBL:BC008058 xref: EMBL:BC014270 xref: EMBL:BT007082 xref: EMBL:L14283 xref: EMBL:Z15108 xref: HGNC:HGNC:9412 xref: UniGene:Hs.496255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005315 ! KPCZ_HUMAN relationship: codes_for CCO:B0025049 ! A6PVX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004960 name: KRTAP4-12_human def: "Keratin-associated protein 4-12 gene" [UniProtKB:Q9BQ66] synonym: "KAP4.12" EXACT [UniProtKB:Q9BQ66] synonym: "KRTAP4.12" EXACT [UniProtKB:Q9BQ66] xref: EMBL:AJ406943 xref: EMBL:BC004180 xref: EMBL:BC004212 xref: EMBL:BC101159 xref: EMBL:BC101160 xref: EMBL:BC101162 xref: HGNC:HGNC:16776 xref: UniGene:Hs.572443 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005293 ! KR412_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004961 name: RPS6KA4_human def: "Ribosomal protein S6 kinase alpha-4 gene" [UniProtKB:O75676] synonym: "MSK2" EXACT [UniProtKB:O75676] xref: EMBL:AF074715 xref: EMBL:AJ010119 xref: EMBL:AK223561 xref: HGNC:HGNC:10433 xref: UniGene:Hs.105584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005629 ! KS6A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004962 name: RPS6KB2_human def: "Ribosomal protein S6 kinase beta-2 gene" [UniProtKB:Q9UBS0] synonym: "STK14B" EXACT [UniProtKB:Q9UBS0] xref: EMBL:AB016869 xref: EMBL:AB019245 xref: EMBL:AF076931 xref: EMBL:AF099739 xref: EMBL:BC000094 xref: HGNC:HGNC:10437 xref: UniGene:Hs.534345 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002193 ! KS6B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004963 name: KATNA1_human def: "Katanin p60 ATPase-containing subunit A1 gene" [UniProtKB:O75449] xref: EMBL:AF056022 xref: EMBL:AL078581 xref: EMBL:BC050428 xref: EMBL:BX276089 xref: HGNC:HGNC:6216 xref: UniGene:Hs.450175 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001427 ! KTNA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004964 name: KATNB1_human def: "Katanin p80 WD40-containing subunit B1 gene" [UniProtKB:Q9BVA0] xref: EMBL:AC092118 xref: EMBL:AF052432 xref: EMBL:BC001353 xref: EMBL:BT007022 xref: EMBL:CH471092 xref: EMBL:CR456762 xref: HGNC:HGNC:6217 xref: UniGene:Hs.275675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002100 ! KTNB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004965 name: XRCC6_human def: "ATP-dependent DNA helicase 2 subunit 1 gene" [UniProtKB:P12956] synonym: "G22P1" EXACT [UniProtKB:P12956] xref: EMBL:AY870329 xref: EMBL:BC008343 xref: EMBL:BC010034 xref: EMBL:BC012154 xref: EMBL:BC018259 xref: EMBL:BC072449 xref: EMBL:CR542219 xref: EMBL:J04607 xref: EMBL:J04611 xref: EMBL:M32865 xref: EMBL:S38729 xref: EMBL:Z83840 xref: HGNC:HGNC:4055 xref: UniGene:Hs.292493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005410 ! KU70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004966 name: XRCC5_human def: "ATP-dependent DNA helicase 2 subunit 2 gene" [UniProtKB:P13010] synonym: "G22P2" EXACT [UniProtKB:P13010] xref: EMBL:AK222603 xref: EMBL:AK290740 xref: EMBL:BC019027 xref: EMBL:BC095442 xref: EMBL:CH471063 xref: EMBL:DQ787434 xref: EMBL:J04977 xref: EMBL:M30938 xref: EMBL:X57500 xref: HGNC:HGNC:12833 xref: UniGene:Hs.388739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005466 ! KU86_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004967 name: LLGL2_human def: "Lethal(2) giant larvae protein homolog 2 gene" [UniProtKB:Q6P1M3] xref: EMBL:BC006503 xref: EMBL:BC010879 xref: EMBL:BC064994 xref: EMBL:X87342 xref: HGNC:HGNC:6629 xref: UniGene:Hs.514477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001913 ! L2GL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004968 name: LAMA4_human def: "Laminin subunit alpha-4 precursor gene" [UniProtKB:Q16363] xref: EMBL:AB210027 xref: EMBL:AL590106 xref: EMBL:S78569 xref: EMBL:X70904 xref: EMBL:X76939 xref: EMBL:X91171 xref: EMBL:Y14240 xref: EMBL:Z99289 xref: HGNC:HGNC:6484 xref: UniGene:Hs.654572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006093 ! LAMA4_HUMAN relationship: codes_for CCO:B0056431 ! Q5H8W3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004969 name: LAMB1_human def: "Laminin subunit beta-1 precursor gene" [UniProtKB:P07942] xref: EMBL:BC113455 xref: EMBL:CH236947 xref: EMBL:M20206 xref: EMBL:M55344 xref: EMBL:M55345 xref: EMBL:M55346 xref: EMBL:M55347 xref: EMBL:M55348 xref: EMBL:M55349 xref: EMBL:M55350 xref: EMBL:M55351 xref: EMBL:M55352 xref: EMBL:M55353 xref: EMBL:M55355 xref: EMBL:M55356 xref: EMBL:M55357 xref: EMBL:M55358 xref: EMBL:M55359 xref: EMBL:M55360 xref: EMBL:M55361 xref: EMBL:M55362 xref: EMBL:M55363 xref: EMBL:M55364 xref: EMBL:M55365 xref: EMBL:M55366 xref: EMBL:M55367 xref: EMBL:M55368 xref: EMBL:M55369 xref: EMBL:M55370 xref: EMBL:M55371 xref: EMBL:M55372 xref: EMBL:M55373 xref: EMBL:M55374 xref: EMBL:M55375 xref: EMBL:M55376 xref: EMBL:M55378 xref: EMBL:M58147 xref: EMBL:M61916 xref: EMBL:M61917 xref: EMBL:M61918 xref: EMBL:M61921 xref: EMBL:M61922 xref: EMBL:M61923 xref: EMBL:M61924 xref: EMBL:M61925 xref: EMBL:M61926 xref: EMBL:M61927 xref: EMBL:M61928 xref: EMBL:M61929 xref: EMBL:M61930 xref: EMBL:M61931 xref: EMBL:M61932 xref: EMBL:M61933 xref: EMBL:M61934 xref: EMBL:M61935 xref: EMBL:M61936 xref: EMBL:M61938 xref: EMBL:M61939 xref: EMBL:M61940 xref: EMBL:M61941 xref: EMBL:M61942 xref: EMBL:M61943 xref: EMBL:M61944 xref: EMBL:M61945 xref: EMBL:M61946 xref: EMBL:M61947 xref: EMBL:M61948 xref: EMBL:M61949 xref: EMBL:M61950 xref: EMBL:M61951 xref: HGNC:HGNC:6486 xref: UniGene:Hs.650585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005967 ! LAMB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004970 name: ERBB2IP_human def: "Protein LAP2 gene" [UniProtKB:Q96RT1] synonym: "ERBIN" EXACT [UniProtKB:Q96RT1] synonym: "KIAA1225" EXACT [UniProtKB:Q96RT1] synonym: "LAP2" EXACT [UniProtKB:Q96RT1] xref: EMBL:AB033051 xref: EMBL:AF263744 xref: EMBL:AF276423 xref: EMBL:AK001180 xref: EMBL:BC050692 xref: HGNC:HGNC:15842 xref: UniGene:Hs.591774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002059 ! LAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004971 name: LATS1_human def: "Serine/threonine-protein kinase LATS1 gene" [UniProtKB:O95835] synonym: "WARTS" EXACT [UniProtKB:O95835] xref: EMBL:AF104413 xref: EMBL:AF164041 xref: EMBL:BC002767 xref: HGNC:HGNC:6514 xref: UniGene:Hs.549084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001454 ! LATS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004972 name: LATS2_human def: "Serine/threonine-protein kinase LATS2 gene" [UniProtKB:Q9NRM7] synonym: "KPM" EXACT [UniProtKB:Q9NRM7] xref: EMBL:AB028019 xref: EMBL:AF207547 xref: EMBL:AK314235 xref: EMBL:AL161613 xref: EMBL:AL356285 xref: EMBL:CH471075 xref: HGNC:HGNC:6515 xref: UniGene:Hs.78960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002159 ! LATS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004973 name: LUC7L2_human def: "Putative RNA-binding protein Luc7-like 2 gene" [UniProtKB:Q9Y383] synonym: "CGI-59" EXACT [UniProtKB:Q9Y383] synonym: "CGI-74" EXACT [UniProtKB:Q9Y383] xref: EMBL:AF151817 xref: EMBL:AF151832 xref: EMBL:AK001476 xref: EMBL:AK001519 xref: EMBL:AK022895 xref: EMBL:BC017163 xref: EMBL:BC042625 xref: EMBL:BC050708 xref: EMBL:BC056886 xref: HGNC:HGNC:21608 xref: UniGene:Hs.370475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006150 ! LC7L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004974 name: LCK_human def: "Proto-oncogene tyrosine-protein kinase LCK gene" [UniProtKB:P06239] xref: EMBL:AF228313 xref: EMBL:AL121991 xref: EMBL:BC013200 xref: EMBL:M21510 xref: EMBL:M26692 xref: EMBL:M36881 xref: EMBL:U07236 xref: EMBL:U23852 xref: EMBL:X04476 xref: EMBL:X05027 xref: EMBL:X06369 xref: EMBL:X13529 xref: EMBL:X14053 xref: EMBL:X14054 xref: EMBL:X14055 xref: HGNC:HGNC:6524 xref: UniGene:Hs.470627 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001490 ! LCK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004975 name: LDOC1_human def: "Protein LDOC1 gene" [UniProtKB:O95751] synonym: "BCUR1" EXACT [UniProtKB:O95751] xref: EMBL:AB019527 xref: EMBL:AL109799 xref: EMBL:BC003104 xref: EMBL:CR457088 xref: HGNC:HGNC:6548 xref: UniGene:Hs.45231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005202 ! LDOC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004976 name: LEPR_human def: "Leptin receptor precursor gene" [UniProtKB:P48357] synonym: "DB" EXACT [UniProtKB:P48357] synonym: "OBR" EXACT [UniProtKB:P48357] xref: EMBL:U43168 xref: EMBL:U50748 xref: EMBL:U52912 xref: EMBL:U52913 xref: EMBL:U52914 xref: EMBL:U59248 xref: EMBL:U59249 xref: EMBL:U59250 xref: EMBL:U59252 xref: EMBL:U59253 xref: EMBL:U59254 xref: EMBL:U59255 xref: EMBL:U59256 xref: EMBL:U59257 xref: EMBL:U59258 xref: EMBL:U59259 xref: EMBL:U59260 xref: EMBL:U59261 xref: EMBL:U59262 xref: EMBL:U59263 xref: EMBL:U66495 xref: EMBL:U66496 xref: EMBL:U66497 xref: HGNC:HGNC:6554 xref: UniGene:Hs.705413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005902 ! LEPR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004977 name: DLEU1_human def: "Leukemia-associated protein 1 gene" [UniProtKB:O43261] synonym: "LEU1" EXACT [UniProtKB:O43261] xref: EMBL:AF328925 xref: EMBL:AL137060 xref: EMBL:BC020692 xref: EMBL:Y15227 xref: EMBL:Y15381 xref: HGNC:HGNC:13747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001385 ! LEU1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004978 name: DLEU2_human def: "Leukemia-associated protein 2 gene" [UniProtKB:O43262] synonym: "LEU2" EXACT [UniProtKB:O43262] xref: EMBL:BC017819 xref: EMBL:BC022282 xref: EMBL:BC030971 xref: EMBL:BC055417 xref: EMBL:BC070292 xref: EMBL:CH471075 xref: EMBL:Y15228 xref: HGNC:HGNC:13748 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001386 ! LEU2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004979 name: LOH11CR2A_human def: "Loss of heterozygosity 11 chromosomal region 2 gene A protein gene" [UniProtKB:O00534] synonym: "BCSC1" EXACT [UniProtKB:O00534] xref: EMBL:AF002672 xref: EMBL:AY366501 xref: EMBL:AY366503 xref: EMBL:AY366504 xref: EMBL:AY366505 xref: EMBL:AY366506 xref: EMBL:AY366507 xref: EMBL:AY366508 xref: EMBL:BC001234 xref: EMBL:BT006655 xref: HGNC:HGNC:6658 xref: UniGene:Hs.152944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001350 ! LHR2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004980 name: LIMK1_human def: "LIM domain kinase 1 gene" [UniProtKB:P53667] synonym: "LIMK" EXACT [UniProtKB:P53667] xref: EMBL:AC005056 xref: EMBL:AC005057 xref: EMBL:AF134379 xref: EMBL:D26309 xref: EMBL:U62293 xref: EMBL:U63721 xref: HGNC:HGNC:6613 xref: UniGene:Hs.647035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005606 ! LIMK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004981 name: LIN9_human def: "Lin-9 homolog gene" [UniProtKB:Q5TKA1] synonym: "BARA" EXACT [UniProtKB:Q5TKA1] synonym: "TGS" EXACT [UniProtKB:Q5TKA1] xref: EMBL:AF190323 xref: EMBL:AF190324 xref: EMBL:AK126177 xref: EMBL:AY786184 xref: EMBL:BC043444 xref: EMBL:BC045625 xref: EMBL:BX537869 xref: HGNC:HGNC:30830 xref: UniGene:Hs.120817 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001894 ! LIN9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004982 name: PPFIA2_human def: "Liprin-alpha-2 gene" [UniProtKB:O75334] xref: EMBL:AF034799 xref: HGNC:HGNC:9246 xref: UniGene:Hs.506216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005602 ! LIPA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004983 name: PAFAH1B1_human def: "Platelet-activating factor acetylhydrolase IB subunit alpha gene" [UniProtKB:P43034] synonym: "LIS1" EXACT [UniProtKB:P43034] synonym: "MDCR" EXACT [UniProtKB:P43034] synonym: "MDS" EXACT [UniProtKB:P43034] synonym: "PAFAHA" EXACT [UniProtKB:P43034] xref: EMBL:AF208837 xref: EMBL:AF208838 xref: EMBL:AF400434 xref: EMBL:BC064638 xref: EMBL:BX538346 xref: EMBL:L13385 xref: EMBL:L13386 xref: EMBL:L13387 xref: EMBL:U72334 xref: EMBL:U72335 xref: EMBL:U72336 xref: EMBL:U72337 xref: EMBL:U72338 xref: EMBL:U72339 xref: EMBL:U72340 xref: EMBL:U72341 xref: EMBL:U72342 xref: HGNC:HGNC:8574 xref: UniGene:Hs.77318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001618 ! LIS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004984 name: LMLN_human def: "Leishmanolysin-like peptidase gene" [UniProtKB:Q96KR4] xref: EMBL:AJ312398 xref: EMBL:AJ312399 xref: HGNC:HGNC:15991 xref: UniGene:Hs.518540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002047 ! LMLN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004985 name: LNX1_human def: "E3 ubiquitin-protein ligase LNX gene" [UniProtKB:Q8TBB1] synonym: "LNX" EXACT [UniProtKB:Q8TBB1] synonym: "UNQ574/PRO1136" EXACT [UniProtKB:Q8TBB1] xref: EMBL:AC058822 xref: EMBL:AC095040 xref: EMBL:AF237782 xref: EMBL:AK056823 xref: EMBL:AY358326 xref: EMBL:BC022983 xref: EMBL:BC034737 xref: HGNC:HGNC:6657 xref: UniGene:Hs.655269 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005305 ! LNX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004986 name: PPAP2B_human def: "Lipid phosphate phosphohydrolase 3 gene" [UniProtKB:O14495] synonym: "LPP3" EXACT [UniProtKB:O14495] xref: EMBL:AB000889 xref: EMBL:AF017786 xref: EMBL:AF043329 xref: EMBL:AF480883 xref: EMBL:BC009196 xref: EMBL:U79294 xref: HGNC:HGNC:9229 xref: UniGene:Hs.405156 xref: UniGene:Hs.702862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006019 ! LPP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004987 name: LRPPRC_human def: "Leucine-rich PPR motif-containing protein, mitochondrial precursor gene" [UniProtKB:P42704] synonym: "LRP130" EXACT [UniProtKB:P42704] xref: EMBL:AC108476 xref: EMBL:AC127379 xref: EMBL:AK125781 xref: EMBL:AK290016 xref: EMBL:AY289212 xref: EMBL:BC010282 xref: EMBL:BC026034 xref: EMBL:BC050311 xref: EMBL:BC130285 xref: EMBL:M92439 xref: HGNC:HGNC:15714 xref: UniGene:Hs.368084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005755 ! LPPRC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004988 name: LRRC59_human def: "Leucine-rich repeat-containing protein 59 gene" [UniProtKB:Q96AG4] synonym: "PRO1855" EXACT [UniProtKB:Q96AG4] xref: EMBL:AF119857 xref: EMBL:BC017168 xref: EMBL:BC052279 xref: HGNC:HGNC:28817 xref: UniGene:Hs.370927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005845 ! LRC59_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004989 name: LRSAM1_human def: "E3 ubiquitin-protein ligase LRSAM1 gene" [UniProtKB:Q6UWE0] synonym: "TAL" EXACT [UniProtKB:Q6UWE0] synonym: "UNQ6496/PRO21356" EXACT [UniProtKB:Q6UWE0] xref: EMBL:AK056203 xref: EMBL:AK056305 xref: EMBL:AK091589 xref: EMBL:AL445222 xref: EMBL:AY358830 xref: EMBL:BC009239 xref: HGNC:HGNC:25135 xref: UniGene:Hs.495188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006335 ! LRSM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004990 name: AOF2_human def: "Lysine-specific histone demethylase 1 gene" [UniProtKB:O60341] synonym: "KIAA0601" EXACT [UniProtKB:O60341] synonym: "LSD1" EXACT [UniProtKB:O60341] xref: EMBL:AB011173 xref: EMBL:AL031428 xref: EMBL:AL833812 xref: EMBL:BC016639 xref: EMBL:BC025362 xref: EMBL:BC040194 xref: EMBL:BC048134 xref: HGNC:HGNC:29079 xref: UniGene:Hs.591518 xref: UniGene:Hs.656420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005589 ! LSD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004991 name: LSM1_human def: "U6 snRNA-associated Sm-like protein LSm1 gene" [UniProtKB:O15116] synonym: "CASM" EXACT [UniProtKB:O15116] xref: EMBL:AF000177 xref: EMBL:AJ238094 xref: EMBL:BC001767 xref: HGNC:HGNC:20472 xref: UniGene:Hs.425311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006005 ! LSM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004992 name: LSM3_human def: "U6 snRNA-associated Sm-like protein LSm3 gene" [UniProtKB:P62310] synonym: "MDS017" EXACT [UniProtKB:P62310] xref: EMBL:AF182289 xref: EMBL:AF182418 xref: EMBL:AJ238095 xref: EMBL:BC007055 xref: HGNC:HGNC:17874 xref: UniGene:Hs.111632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005566 ! LSM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004993 name: LSM6_human def: "U6 snRNA-associated Sm-like protein LSm6 gene" [UniProtKB:P62312] xref: EMBL:AF182292 xref: EMBL:AJ238098 xref: EMBL:BC016026 xref: HGNC:HGNC:17017 xref: UniGene:Hs.190520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005567 ! LSM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004994 name: LSM7_human def: "U6 snRNA-associated Sm-like protein LSm7 gene" [UniProtKB:Q9UK45] xref: EMBL:AC005258 xref: EMBL:AF182293 xref: EMBL:BC018621 xref: HGNC:HGNC:20470 xref: UniGene:Hs.512610 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005494 ! LSM7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004995 name: LSM8_human def: "U6 snRNA-associated Sm-like protein LSm8 gene" [UniProtKB:O95777] xref: EMBL:AC006389 xref: EMBL:AF182294 xref: EMBL:BC002742 xref: EMBL:BC022440 xref: HGNC:HGNC:20471 xref: UniGene:Hs.657737 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005349 ! LSM8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004996 name: LTBP2_human def: "Latent-transforming growth factor beta-binding protein 2 precursor gene" [UniProtKB:Q14767] synonym: "C14orf141" EXACT [UniProtKB:Q14767] synonym: "LTBP3" EXACT [UniProtKB:Q14767] xref: EMBL:AC013451 xref: EMBL:S82451 xref: EMBL:Z37976 xref: HGNC:HGNC:6715 xref: UniGene:Hs.512776 xref: UniGene:Hs.597522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001791 ! LTBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004997 name: ALOX15B_human def: "Arachidonate 15-lipoxygenase type II gene" [UniProtKB:O15296] xref: EMBL:AF149095 xref: EMBL:AF468051 xref: EMBL:AF468052 xref: EMBL:AF468053 xref: EMBL:AF468054 xref: EMBL:AJ305028 xref: EMBL:AJ305029 xref: EMBL:AJ305030 xref: EMBL:AJ305031 xref: EMBL:BC035217 xref: EMBL:BC063647 xref: EMBL:U78294 xref: HGNC:HGNC:434 xref: UniGene:Hs.111256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001371 ! LX15B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004998 name: LYN_human def: "Tyrosine-protein kinase Lyn gene" [UniProtKB:P07948] xref: EMBL:BC075001 xref: EMBL:BC075002 xref: EMBL:BC126456 xref: EMBL:BC126458 xref: EMBL:M16038 xref: EMBL:M79321 xref: HGNC:HGNC:6735 xref: UniGene:Hs.699154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005457 ! LYN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0004999 name: LYPLA2_human def: "Acyl-protein thioesterase 2 gene" [UniProtKB:O95372] xref: EMBL:AF090423 xref: EMBL:AF098668 xref: EMBL:AL031295 xref: EMBL:BC017034 xref: EMBL:BC017193 xref: HGNC:HGNC:6738 xref: UniGene:Hs.533479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006282 ! LYPA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005000 name: LZTS1_human def: "Leucine zipper putative tumor suppressor 1 gene" [UniProtKB:Q9Y250] synonym: "FEZ1" EXACT [UniProtKB:Q9Y250] xref: EMBL:AF123652 xref: EMBL:AF123653 xref: EMBL:AF123654 xref: EMBL:AF123655 xref: EMBL:AF123656 xref: EMBL:AF123657 xref: EMBL:AF123658 xref: EMBL:AF123659 xref: EMBL:BC075006 xref: EMBL:BC075007 xref: HGNC:HGNC:13861 xref: UniGene:Hs.521432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002248 ! LZTS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005001 name: LZTS2_human def: "Leucine zipper putative tumor suppressor 2 gene" [UniProtKB:Q9BRK4] synonym: "KIAA1813" EXACT [UniProtKB:Q9BRK4] synonym: "LAPSER1" EXACT [UniProtKB:Q9BRK4] xref: EMBL:AB058716 xref: EMBL:AL834338 xref: EMBL:AY029201 xref: EMBL:BC006212 xref: EMBL:BC058938 xref: HGNC:HGNC:29381 xref: UniGene:Hs.523221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002094 ! LZTS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005002 name: MID1IP1_human def: "Mid1-interacting protein 1 gene" [UniProtKB:Q9NPA3] synonym: "MIG12" EXACT [UniProtKB:Q9NPA3] xref: EMBL:AJ272057 xref: EMBL:AK001248 xref: EMBL:BC008908 xref: EMBL:BC019332 xref: EMBL:BK001260 xref: EMBL:CR457220 xref: HGNC:HGNC:20715 xref: UniGene:Hs.522605 xref: UniGene:Hs.705525 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005281 ! M1IP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005003 name: SLC25A11_human def: "Mitochondrial 2-oxoglutarate/malate carrier protein gene" [UniProtKB:Q02978] synonym: "SLC20A4" EXACT [UniProtKB:Q02978] xref: EMBL:AF070548 xref: EMBL:BC006508 xref: EMBL:BC006519 xref: EMBL:BC016294 xref: EMBL:BC017170 xref: EMBL:X66114 xref: HGNC:HGNC:10981 xref: UniGene:Hs.184877 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006316 ! M2OM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005004 name: MAP3K11_human def: "Mitogen-activated protein kinase kinase kinase 11 gene" [UniProtKB:Q16584] synonym: "MLK3" EXACT [UniProtKB:Q16584] synonym: "PTK1" EXACT [UniProtKB:Q16584] synonym: "SPRK" EXACT [UniProtKB:Q16584] xref: EMBL:AB209655 xref: EMBL:AK222781 xref: EMBL:BC011263 xref: EMBL:BC064543 xref: EMBL:L32976 xref: EMBL:U07747 xref: HGNC:HGNC:6850 xref: UniGene:Hs.502872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001820 ! M3K11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005005 name: MAP3K14_human def: "Mitogen-activated protein kinase kinase kinase 14 gene" [UniProtKB:Q99558] synonym: "NIK" EXACT [UniProtKB:Q99558] xref: EMBL:BC035576 xref: EMBL:DQ314874 xref: EMBL:Y10256 xref: HGNC:HGNC:6853 xref: UniGene:Hs.404183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005528 ! M3K14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005006 name: MAP3K1_human def: "Mitogen-activated protein kinase kinase kinase 1 gene" [UniProtKB:Q13233] synonym: "MAPKKK1" EXACT [UniProtKB:Q13233] synonym: "MEKK" EXACT [UniProtKB:Q13233] synonym: "MEKK1" EXACT [UniProtKB:Q13233] xref: EMBL:AC008937 xref: EMBL:AF042838 xref: EMBL:U29671 xref: HGNC:HGNC:6848 xref: UniGene:Hs.657756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005525 ! M3K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005007 name: MAP3K3_human def: "Mitogen-activated protein kinase kinase kinase 3 gene" [UniProtKB:Q99759] synonym: "MAPKKK3" EXACT [UniProtKB:Q99759] synonym: "MEKK3" EXACT [UniProtKB:Q99759] xref: EMBL:BC090859 xref: EMBL:BC093672 xref: EMBL:BC093674 xref: EMBL:CH471109 xref: EMBL:U78876 xref: HGNC:HGNC:6855 xref: UniGene:Hs.29282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005526 ! M3K3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005008 name: MAP3K4_human def: "Mitogen-activated protein kinase kinase kinase 4 gene" [UniProtKB:Q9Y6R4] synonym: "KIAA0213" EXACT [UniProtKB:Q9Y6R4] synonym: "MAPKKK4" EXACT [UniProtKB:Q9Y6R4] synonym: "MEKK4" EXACT [UniProtKB:Q9Y6R4] synonym: "MTK1" EXACT [UniProtKB:Q9Y6R4] xref: EMBL:AF002715 xref: EMBL:D86968 xref: HGNC:HGNC:6856 xref: UniGene:Hs.390428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005915 ! M3K4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005009 name: MAP3K5_human def: "Mitogen-activated protein kinase kinase kinase 5 gene" [UniProtKB:Q99683] synonym: "ASK1" EXACT [UniProtKB:Q99683] synonym: "MAPKKK5" EXACT [UniProtKB:Q99683] synonym: "MEKK5" EXACT [UniProtKB:Q99683] xref: EMBL:AL024508 xref: EMBL:AL121933 xref: EMBL:BC054503 xref: EMBL:BC088829 xref: EMBL:D84476 xref: EMBL:U67156 xref: HGNC:HGNC:6857 xref: UniGene:Hs.186486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005577 ! M3K5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005010 name: MAP3K8_human def: "Mitogen-activated protein kinase kinase kinase 8 gene" [UniProtKB:P41279] synonym: "COT" EXACT [UniProtKB:P41279] synonym: "ESTF" EXACT [UniProtKB:P41279] xref: EMBL:AF133211 xref: EMBL:AL161651 xref: EMBL:AY309013 xref: EMBL:BC104833 xref: EMBL:BC113566 xref: EMBL:D14497 xref: EMBL:Z14138 xref: HGNC:HGNC:6860 xref: UniGene:Hs.432453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005520 ! M3K8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005011 name: MAP4K2_human def: "Mitogen-activated protein kinase kinase kinase kinase 2 gene" [UniProtKB:Q12851] synonym: "GCK" EXACT [UniProtKB:Q12851] synonym: "RAB8IP" EXACT [UniProtKB:Q12851] xref: EMBL:AP001462 xref: EMBL:U07349 xref: HGNC:HGNC:6864 xref: UniGene:Hs.534341 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005706 ! M4K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005012 name: MACF1_human def: "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 gene" [UniProtKB:Q9UPN3] synonym: "ABP620" EXACT [UniProtKB:Q9UPN3] synonym: "ACF7" EXACT [UniProtKB:Q9UPN3] synonym: "KIAA0465" EXACT [UniProtKB:Q9UPN3] synonym: "KIAA1251" EXACT [UniProtKB:Q9UPN3] xref: EMBL:AB007934 xref: EMBL:AB029290 xref: EMBL:AB033077 xref: EMBL:AF141968 xref: EMBL:AF317696 xref: EMBL:AF325330 xref: EMBL:AF325331 xref: EMBL:AF325332 xref: EMBL:AF325333 xref: EMBL:AF325334 xref: EMBL:AF325335 xref: EMBL:AF325336 xref: EMBL:AF325339 xref: EMBL:AF325340 xref: EMBL:AF325341 xref: EMBL:AL137853 xref: EMBL:AL355477 xref: EMBL:AL365277 xref: EMBL:AL442071 xref: HGNC:HGNC:13664 xref: UniGene:Hs.580782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002053 ! MACF4_HUMAN relationship: codes_for CCO:B0002237 ! MACF1_HUMAN relationship: codes_for CCO:B0041233 ! B1ALC7_HUMAN relationship: codes_for CCO:B0041235 ! B1ANQ7_HUMAN relationship: codes_for CCO:B0041236 ! B1ANR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005013 name: MADD_human def: "MAP kinase-activating death domain protein gene" [UniProtKB:Q8WXG6] synonym: "DENN" EXACT [UniProtKB:Q8WXG6] synonym: "IG20" EXACT [UniProtKB:Q8WXG6] synonym: "KIAA0358" EXACT [UniProtKB:Q8WXG6] xref: EMBL:AB002356 xref: EMBL:AF440100 xref: EMBL:AF440101 xref: EMBL:AF440102 xref: EMBL:AF440103 xref: EMBL:AF440434 xref: EMBL:BC040484 xref: EMBL:U44953 xref: EMBL:U77352 xref: HGNC:HGNC:6766 xref: UniGene:Hs.82548 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002010 ! MADD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005014 name: MAEA_human def: "Macrophage erythroblast attacher gene" [UniProtKB:Q7L5Y9] synonym: "EMP" EXACT [UniProtKB:Q7L5Y9] synonym: "HLC10" EXACT [UniProtKB:Q7L5Y9] synonym: "PIG5" EXACT [UniProtKB:Q7L5Y9] xref: EMBL:AF084928 xref: EMBL:AK001088 xref: EMBL:AK022515 xref: EMBL:AK022586 xref: EMBL:AK128302 xref: EMBL:AY189687 xref: EMBL:AY236486 xref: EMBL:BC001225 xref: EMBL:BC006470 xref: EMBL:BT006957 xref: HGNC:HGNC:13731 xref: UniGene:Hs.139896 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001930 ! MAEA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005015 name: MAF1_human def: "Repressor of RNA polymerase III transcription MAF1 homolog gene" [UniProtKB:Q9H063] xref: EMBL:AL136937 xref: EMBL:BC014082 xref: EMBL:BC018714 xref: EMBL:BC031273 xref: EMBL:CR533463 xref: HGNC:HGNC:24966 xref: UniGene:Hs.19673 xref: UniGene:Hs.529755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005301 ! MAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005016 name: MAGEA11_human def: "Melanoma-associated antigen 11 gene" [UniProtKB:P43364] synonym: "MAGE11" EXACT [UniProtKB:P43364] xref: EMBL:AK127849 xref: EMBL:AY747607 xref: EMBL:BC004479 xref: EMBL:U10686 xref: HGNC:HGNC:6798 xref: UniGene:Hs.670252 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005212 ! MAGAB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005017 name: MAGEA12_human def: "Melanoma-associated antigen 12 gene" [UniProtKB:P43365] synonym: "MAGE12" EXACT [UniProtKB:P43365] xref: EMBL:BC003408 xref: EMBL:BT007108 xref: EMBL:L18877 xref: EMBL:U82671 xref: HGNC:HGNC:6799 xref: UniGene:Hs.169246 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005266 ! MAGAC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005018 name: MAGEB18_human def: "Melanoma-associated antigen B18 gene" [UniProtKB:Q96M61] xref: EMBL:AK057361 xref: EMBL:BC029525 xref: HGNC:HGNC:28515 xref: UniGene:Hs.350683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005185 ! MAGBI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005020 name: MAGED1_human def: "Melanoma-associated antigen D1 gene" [UniProtKB:Q9Y5V3] synonym: "NRAGE" EXACT [UniProtKB:Q9Y5V3] synonym: "PP2250" EXACT [UniProtKB:Q9Y5V3] synonym: "PRO2292" EXACT [UniProtKB:Q9Y5V3] xref: EMBL:AF124440 xref: EMBL:AF132205 xref: EMBL:AF217963 xref: EMBL:AF258554 xref: EMBL:AF300328 xref: EMBL:AL133628 xref: EMBL:AL929410 xref: EMBL:BC014070 xref: EMBL:BC032473 xref: HGNC:HGNC:6813 xref: UniGene:Hs.5258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006204 ! MAGD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005021 name: MAGEH1_human def: "Melanoma-associated antigen H1 gene" [UniProtKB:Q9H213] synonym: "APR1" EXACT [UniProtKB:Q9H213] xref: EMBL:AF143235 xref: EMBL:AF320912 xref: EMBL:AL590410 xref: EMBL:BC011954 xref: HGNC:HGNC:24092 xref: UniGene:Hs.279819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005406 ! MAGH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005022 name: MAP9_human def: "Microtubule-associated protein 9 gene" [UniProtKB:Q49MG5] synonym: "ASAP" EXACT [UniProtKB:Q49MG5] xref: EMBL:AC097467 xref: EMBL:AK024730 xref: EMBL:AK024812 xref: EMBL:AY690636 xref: EMBL:CR749274 xref: HGNC:HGNC:26118 xref: UniGene:Hs.61271 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001834 ! MAP9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005023 name: MAPKAPK5_human def: "MAP kinase-activated protein kinase 5 gene" [UniProtKB:Q8IW41] synonym: "PRAK" EXACT [UniProtKB:Q8IW41] xref: EMBL:AF032437 xref: EMBL:AL110301 xref: EMBL:BC000833 xref: EMBL:BC041049 xref: EMBL:BC047284 xref: HGNC:HGNC:6889 xref: UniGene:Hs.413901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005891 ! MAPK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005024 name: MAPRE1_human def: "Microtubule-associated protein RP/EB family member 1 gene" [UniProtKB:Q15691] xref: EMBL:AL035071 xref: EMBL:BC106068 xref: EMBL:BC109281 xref: EMBL:U24166 xref: HGNC:HGNC:6890 xref: UniGene:Hs.472437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001812 ! MARE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005025 name: MAPRE2_human def: "Microtubule-associated protein RP/EB family member 2 gene" [UniProtKB:Q15555] synonym: "RP1" EXACT [UniProtKB:Q15555] xref: EMBL:AB016823 xref: EMBL:BC007318 xref: EMBL:BT020086 xref: EMBL:CR536545 xref: EMBL:X94232 xref: HGNC:HGNC:6891 xref: UniGene:Hs.532824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001811 ! MARE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005026 name: MAPRE3_human def: "Microtubule-associated protein RP/EB family member 3 gene" [UniProtKB:Q9UPY8] xref: EMBL:AB025186 xref: EMBL:AF288787 xref: EMBL:BC011557 xref: EMBL:CR536523 xref: EMBL:Y11174 xref: HGNC:HGNC:6892 xref: UniGene:Hs.515860 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002238 ! MARE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005027 name: MARK3_human def: "MAP/microtubule affinity-regulating kinase 3 gene" [UniProtKB:P27448] synonym: "CTAK1" EXACT [UniProtKB:P27448] xref: EMBL:AF159295 xref: EMBL:AF170723 xref: EMBL:AF387637 xref: EMBL:AF465413 xref: EMBL:BC024773 xref: EMBL:M80359 xref: EMBL:U64205 xref: HGNC:HGNC:6897 xref: UniGene:Hs.35828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005229 ! MARK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005028 name: MARK4_human def: "MAP/microtubule affinity-regulating kinase 4 gene" [UniProtKB:Q96L34] synonym: "KIAA1860" EXACT [UniProtKB:Q96L34] synonym: "MARKL1" EXACT [UniProtKB:Q96L34] xref: EMBL:AB049127 xref: EMBL:AB058763 xref: EMBL:AB088047 xref: EMBL:AK027619 xref: EMBL:AK075272 xref: EMBL:AY057448 xref: EMBL:AY120867 xref: HGNC:HGNC:13538 xref: UniGene:Hs.34314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005344 ! MARK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005029 name: MAST3_human def: "Microtubule-associated serine/threonine-protein kinase 3 gene" [UniProtKB:O60307] synonym: "KIAA0561" EXACT [UniProtKB:O60307] xref: EMBL:AB011133 xref: EMBL:AC005793 xref: EMBL:AC007192 xref: EMBL:AC093054 xref: HGNC:HGNC:19036 xref: UniGene:Hs.466184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005499 ! MAST3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005030 name: MNAT1_human def: "CDK-activating kinase assembly factor MAT1 gene" [UniProtKB:P51948] synonym: "CAP35" EXACT [UniProtKB:P51948] synonym: "MAT1" EXACT [UniProtKB:P51948] synonym: "RNF66" EXACT [UniProtKB:P51948] xref: EMBL:AY165512 xref: EMBL:BC000820 xref: EMBL:U61835 xref: EMBL:X87843 xref: EMBL:X92669 xref: HGNC:HGNC:7181 xref: UniGene:Hs.509523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001653 ! MAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005031 name: MATK_human def: "Megakaryocyte-associated tyrosine-protein kinase gene" [UniProtKB:P42679] synonym: "CTK" EXACT [UniProtKB:P42679] synonym: "HYL" EXACT [UniProtKB:P42679] xref: EMBL:AC005777 xref: EMBL:BC000114 xref: EMBL:BC003109 xref: EMBL:L18974 xref: EMBL:S75145 xref: EMBL:S75147 xref: EMBL:S75151 xref: EMBL:S75153 xref: EMBL:S75155 xref: EMBL:S75156 xref: EMBL:S75158 xref: EMBL:S75159 xref: EMBL:S75162 xref: EMBL:S75164 xref: EMBL:S75166 xref: EMBL:S75168 xref: EMBL:X77278 xref: HGNC:HGNC:6906 xref: UniGene:Hs.631845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001612 ! MATK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005032 name: MATR3_human def: "Matrin-3 gene" [UniProtKB:P43243] synonym: "KIAA0723" EXACT [UniProtKB:P43243] xref: EMBL:AB018266 xref: EMBL:AF117236 xref: EMBL:BC015031 xref: EMBL:M63483 xref: HGNC:HGNC:6912 xref: UniGene:Hs.268939 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005968 ! MATR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005033 name: MAX_human def: "Protein max gene" [UniProtKB:P61244] xref: EMBL:AL139022 xref: EMBL:BC003525 xref: EMBL:BC004516 xref: EMBL:BC013669 xref: EMBL:BC027924 xref: EMBL:M64240 xref: EMBL:X60287 xref: EMBL:X66867 xref: HGNC:HGNC:6913 xref: UniGene:Hs.285354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005336 ! MAX_HUMAN relationship: codes_for CCO:B0053843 ! A6NH73_HUMAN relationship: codes_for CCO:B0058187 ! Q96CY8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005034 name: MBD1_human def: "Methyl-CpG-binding domain protein 1 gene" [UniProtKB:Q9UIS9] synonym: "CXXC3" EXACT [UniProtKB:Q9UIS9] synonym: "PCM1" EXACT [UniProtKB:Q9UIS9] xref: EMBL:AF072241 xref: EMBL:AF078830 xref: EMBL:AF078831 xref: EMBL:AF078832 xref: EMBL:AF078833 xref: EMBL:AF120980 xref: EMBL:AF120981 xref: EMBL:AJ564845 xref: EMBL:BC033242 xref: EMBL:EF488685 xref: EMBL:Y10746 xref: HGNC:HGNC:6916 xref: UniGene:Hs.405610 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005510 ! MBD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005035 name: MBIP_human def: "MAP3K12-binding inhibitory protein 1 gene" [UniProtKB:Q9NS73] synonym: "BM-015" EXACT [UniProtKB:Q9NS73] xref: EMBL:AB038523 xref: EMBL:AF208857 xref: EMBL:BC005197 xref: EMBL:BC016821 xref: EMBL:BX248287 xref: HGNC:HGNC:20427 xref: UniGene:Hs.368647 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005271 ! MBIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005036 name: MCM10_human def: "Protein MCM10 homolog gene" [UniProtKB:Q7L590] synonym: "PRO2249" EXACT [UniProtKB:Q7L590] xref: EMBL:AB042719 xref: EMBL:AF119869 xref: EMBL:AK055695 xref: EMBL:AL136840 xref: EMBL:AL138764 xref: EMBL:AL355355 xref: EMBL:BC004876 xref: EMBL:BC101727 xref: HGNC:HGNC:18043 xref: UniGene:Hs.198363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001929 ! MCM10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005037 name: MCM2_human def: "DNA replication licensing factor MCM2 gene" [UniProtKB:P49736] synonym: "BM28" EXACT [UniProtKB:P49736] synonym: "CCNL1" EXACT [UniProtKB:P49736] synonym: "CDCL1" EXACT [UniProtKB:P49736] synonym: "KIAA0030" EXACT [UniProtKB:P49736] xref: EMBL:AY675259 xref: EMBL:BC006165 xref: EMBL:BC007670 xref: EMBL:BC007938 xref: EMBL:BC014272 xref: EMBL:BC017258 xref: EMBL:BC017490 xref: EMBL:BC030131 xref: EMBL:BT009734 xref: EMBL:D21063 xref: EMBL:D83987 xref: EMBL:X67334 xref: HGNC:HGNC:6944 xref: UniGene:Hs.477481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001631 ! MCM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005038 name: MCM3_human def: "DNA replication licensing factor MCM3 gene" [UniProtKB:P25205] xref: EMBL:AL034343 xref: EMBL:AY621074 xref: EMBL:BC001626 xref: EMBL:BC003509 xref: EMBL:D38073 xref: EMBL:X62153 xref: HGNC:HGNC:6945 xref: UniGene:Hs.179565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001558 ! MCM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005039 name: MCM4_human def: "DNA replication licensing factor MCM4 gene" [UniProtKB:P33991] synonym: "CDC21" EXACT [UniProtKB:P33991] xref: EMBL:AY588245 xref: EMBL:BC031061 xref: EMBL:U63630 xref: EMBL:U90415 xref: EMBL:X74794 xref: HGNC:HGNC:6947 xref: UniGene:Hs.460184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005391 ! MCM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005040 name: MCM5_human def: "DNA replication licensing factor MCM5 gene" [UniProtKB:P33992] synonym: "CDC46" EXACT [UniProtKB:P33992] xref: EMBL:AY212028 xref: EMBL:BC000142 xref: EMBL:BC003656 xref: EMBL:CH471095 xref: EMBL:CR456517 xref: EMBL:D83986 xref: EMBL:X74795 xref: EMBL:Z82244 xref: HGNC:HGNC:6948 xref: UniGene:Hs.517582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001588 ! MCM5_HUMAN relationship: codes_for CCO:B0048576 ! B1AHB1_HUMAN relationship: codes_for CCO:B0054209 ! B1AHA9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005041 name: MCM6_human def: "DNA replication licensing factor MCM6 gene" [UniProtKB:Q14566] xref: EMBL:AY220757 xref: EMBL:BC032374 xref: EMBL:D84557 xref: EMBL:U46838 xref: EMBL:U67281 xref: EMBL:U67282 xref: EMBL:U67283 xref: EMBL:U67284 xref: HGNC:HGNC:6949 xref: UniGene:Hs.444118 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001785 ! MCM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005042 name: MCM7_human def: "DNA replication licensing factor MCM7 gene" [UniProtKB:P33993] synonym: "CDC47" EXACT [UniProtKB:P33993] synonym: "MCM2" EXACT [UniProtKB:P33993] xref: EMBL:AK055379 xref: EMBL:BC009398 xref: EMBL:BC013375 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: EMBL:D28480 xref: EMBL:D55716 xref: EMBL:X74796 xref: HGNC:HGNC:6950 xref: UniGene:Hs.438720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001589 ! MCM7_HUMAN relationship: codes_for CCO:B0017892 ! A4D2A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005043 name: MCM8_human def: "DNA replication licensing factor MCM8 gene" [UniProtKB:Q9UJA3] synonym: "C20orf154" EXACT [UniProtKB:Q9UJA3] xref: EMBL:AJ439063 xref: EMBL:AK027644 xref: EMBL:AL035461 xref: EMBL:AY158211 xref: EMBL:BC008830 xref: EMBL:BC080656 xref: EMBL:BC101054 xref: EMBL:BC101056 xref: EMBL:BC101057 xref: HGNC:HGNC:16147 xref: UniGene:Hs.631506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002210 ! MCM8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005044 name: MCRS1_human def: "Microspherule protein 1 gene" [UniProtKB:Q96EZ8] synonym: "INO80Q" EXACT [UniProtKB:Q96EZ8] synonym: "MSP58" EXACT [UniProtKB:Q96EZ8] xref: EMBL:AF015308 xref: EMBL:AF068007 xref: EMBL:AY336730 xref: EMBL:BC011794 xref: HGNC:HGNC:6960 xref: UniGene:Hs.25313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002036 ! MCRS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005045 name: MED13L_human def: "Mediator of RNA polymerase II transcription subunit 13-like gene" [UniProtKB:Q71F56] synonym: "KIAA1025" EXACT [UniProtKB:Q71F56] synonym: "PROSIT240" EXACT [UniProtKB:Q71F56] synonym: "THRAP2" EXACT [UniProtKB:Q71F56] synonym: "TRAP240L" EXACT [UniProtKB:Q71F56] xref: EMBL:AB028948 xref: EMBL:AF515599 xref: EMBL:AK023837 xref: EMBL:AL133033 xref: EMBL:AL137644 xref: EMBL:AY338463 xref: EMBL:BC130422 xref: EMBL:CR749332 xref: HGNC:HGNC:22962 xref: UniGene:Hs.654691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005801 ! MD13L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005046 name: MAD1L1_human def: "Mitotic spindle assembly checkpoint protein MAD1 gene" [UniProtKB:Q9Y6D9] synonym: "MAD1" EXACT [UniProtKB:Q9Y6D9] synonym: "TXBP181" EXACT [UniProtKB:Q9Y6D9] xref: EMBL:AC005282 xref: EMBL:AC006433 xref: EMBL:AC069288 xref: EMBL:AC104129 xref: EMBL:AC110781 xref: EMBL:AF083811 xref: EMBL:AF123318 xref: EMBL:BC009964 xref: EMBL:U33822 xref: HGNC:HGNC:6762 xref: UniGene:Hs.654838 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002264 ! MD1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005047 name: MAD2L1BP_human def: "MAD2L1-binding protein gene" [UniProtKB:Q15013] synonym: "CMT2" EXACT [UniProtKB:Q15013] synonym: "KIAA0110" EXACT [UniProtKB:Q15013] xref: EMBL:AL136131 xref: EMBL:AL353602 xref: EMBL:BC002904 xref: EMBL:D14811 xref: HGNC:HGNC:21059 xref: UniGene:Hs.122346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001341 ! A6NMP7_HUMAN relationship: codes_for CCO:B0001799 ! MD2BP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005048 name: MAD2L1_human def: "Mitotic spindle assembly checkpoint protein MAD2A gene" [UniProtKB:Q13257] synonym: "MAD2" EXACT [UniProtKB:Q13257] xref: EMBL:AB056160 xref: EMBL:AF394735 xref: EMBL:AJ000186 xref: EMBL:AK298228 xref: EMBL:BC000356 xref: EMBL:BC005945 xref: EMBL:CH471056 xref: EMBL:U31278 xref: EMBL:U65410 xref: HGNC:HGNC:6763 xref: UniGene:Hs.591697 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001748 ! MD2L1_HUMAN relationship: codes_for CCO:B0001958 ! Q8IZX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005049 name: MAD2L2_human def: "Mitotic spindle assembly checkpoint protein MAD2B gene" [UniProtKB:Q9UI95] synonym: "MAD2B" EXACT [UniProtKB:Q9UI95] synonym: "REV7" EXACT [UniProtKB:Q9UI95] xref: EMBL:AF072933 xref: EMBL:AF080398 xref: EMBL:AF139365 xref: EMBL:AF157482 xref: EMBL:AL031731 xref: EMBL:BC015244 xref: EMBL:DQ017900 xref: HGNC:HGNC:6764 xref: UniGene:Hs.19400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002204 ! MD2L2_HUMAN relationship: codes_for CCO:B0041228 ! B1AK43_HUMAN relationship: codes_for CCO:B0041229 ! B1AK44_HUMAN relationship: codes_for CCO:B0041230 ! B1AK45_HUMAN relationship: codes_for CCO:B0041231 ! B1AK46_HUMAN relationship: codes_for CCO:B0041232 ! B1AK47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005050 name: MDC1_human def: "Mediator of DNA damage checkpoint protein 1 gene" [UniProtKB:Q14676] synonym: "KIAA0170" EXACT [UniProtKB:Q14676] synonym: "NFBD1" EXACT [UniProtKB:Q14676] xref: EMBL:AB088099 xref: EMBL:AB103605 xref: EMBL:AB202097 xref: EMBL:AL662797 xref: EMBL:AL662848 xref: EMBL:AL845353 xref: EMBL:BA000025 xref: EMBL:BC110645 xref: EMBL:BC131491 xref: EMBL:BC152556 xref: EMBL:BX248307 xref: EMBL:BX927283 xref: EMBL:CH471081 xref: EMBL:CR749828 xref: EMBL:CR759873 xref: EMBL:CR788240 xref: EMBL:CR936878 xref: EMBL:D79992 xref: HGNC:HGNC:21163 xref: UniGene:Hs.519993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001788 ! MDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005051 name: MDFI_human def: "MyoD family inhibitor gene" [UniProtKB:Q99750] xref: EMBL:AL035588 xref: EMBL:BC007836 xref: EMBL:U78313 xref: HGNC:HGNC:6967 xref: UniGene:Hs.520119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005232 ! MDFI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005052 name: MDM2_human def: "E3 ubiquitin-protein ligase Mdm2 gene" [UniProtKB:Q00987] xref: EMBL:AF092844 xref: EMBL:AF092845 xref: EMBL:AF201370 xref: EMBL:AF527840 xref: EMBL:AJ251943 xref: EMBL:BT007258 xref: EMBL:M92424 xref: EMBL:U28935 xref: EMBL:U33199 xref: EMBL:U33200 xref: EMBL:U33201 xref: EMBL:U33202 xref: EMBL:U33203 xref: EMBL:U39736 xref: EMBL:Z12020 xref: HGNC:HGNC:6973 xref: UniGene:Hs.567303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001712 ! MDM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005053 name: MDM4_human def: "Protein Mdm4 gene" [UniProtKB:O15151] synonym: "MDMX" EXACT [UniProtKB:O15151] xref: EMBL:AF007111 xref: EMBL:AK223228 xref: EMBL:AL512306 xref: EMBL:AY207458 xref: EMBL:BC067299 xref: HGNC:HGNC:6974 xref: UniGene:Hs.702385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001366 ! MDM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005054 name: MED10_human def: "Mediator of RNA polymerase II transcription subunit 10 gene" [UniProtKB:Q9BTT4] synonym: "L6" EXACT [UniProtKB:Q9BTT4] synonym: "TRG17" EXACT [UniProtKB:Q9BTT4] synonym: "TRG20" EXACT [UniProtKB:Q9BTT4] xref: EMBL:AY277599 xref: EMBL:AY453397 xref: EMBL:AY598325 xref: EMBL:BC003353 xref: EMBL:CH471102 xref: HGNC:HGNC:28760 xref: UniGene:Hs.13885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005573 ! MED10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005055 name: MED11_human def: "Mediator of RNA polymerase II transcription subunit 11 gene" [UniProtKB:Q9P086] synonym: "HSPC296" EXACT [UniProtKB:Q9P086] xref: EMBL:AF161414 xref: EMBL:BC070377 xref: EMBL:CH471108 xref: HGNC:HGNC:32687 xref: UniGene:Hs.513885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005796 ! MED11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005056 name: MED12_human def: "Mediator of RNA polymerase II transcription subunit 12 gene" [UniProtKB:Q93074] synonym: "ARC240" EXACT [UniProtKB:Q93074] synonym: "CAGH45" EXACT [UniProtKB:Q93074] synonym: "HOPA" EXACT [UniProtKB:Q93074] synonym: "KIAA0192" EXACT [UniProtKB:Q93074] synonym: "TNRC11" EXACT [UniProtKB:Q93074] synonym: "TRAP230" EXACT [UniProtKB:Q93074] xref: EMBL:AF071309 xref: EMBL:AF117755 xref: EMBL:AF132033 xref: EMBL:AL590764 xref: EMBL:D83783 xref: EMBL:U80742 xref: HGNC:HGNC:11957 xref: UniGene:Hs.409226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005789 ! MED12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005057 name: MED13_human def: "Mediator of RNA polymerase II transcription subunit 13 gene" [UniProtKB:Q9UHV7] synonym: "ARC250" EXACT [UniProtKB:Q9UHV7] synonym: "KIAA0593" EXACT [UniProtKB:Q9UHV7] synonym: "THRAP1" EXACT [UniProtKB:Q9UHV7] synonym: "TRAP240" EXACT [UniProtKB:Q9UHV7] xref: EMBL:AB011165 xref: EMBL:AF117754 xref: HGNC:HGNC:22474 xref: UniGene:Hs.282678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005794 ! MED13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005058 name: MED14_human def: "Mediator of RNA polymerase II transcription subunit 14 gene" [UniProtKB:O60244] synonym: "ARC150" EXACT [UniProtKB:O60244] synonym: "CRSP2" EXACT [UniProtKB:O60244] synonym: "CXorf4" EXACT [UniProtKB:O60244] synonym: "DRIP150" EXACT [UniProtKB:O60244] synonym: "EXLM1" EXACT [UniProtKB:O60244] synonym: "RGR1" EXACT [UniProtKB:O60244] synonym: "TRAP170" EXACT [UniProtKB:O60244] xref: EMBL:AB006651 xref: EMBL:AB006652 xref: EMBL:AF104256 xref: EMBL:AF135802 xref: EMBL:AF304448 xref: EMBL:BC098377 xref: EMBL:BC132672 xref: EMBL:BC132674 xref: HGNC:HGNC:2370 xref: UniGene:Hs.407604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005800 ! MED14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005059 name: MED15_human def: "Mediator of RNA polymerase II transcription subunit 15 gene" [UniProtKB:Q96RN5] synonym: "ARC105" EXACT [UniProtKB:Q96RN5] synonym: "CTG7A" EXACT [UniProtKB:Q96RN5] synonym: "PCQAP" EXACT [UniProtKB:Q96RN5] synonym: "TIG1" EXACT [UniProtKB:Q96RN5] synonym: "TNRC7" EXACT [UniProtKB:Q96RN5] xref: EMBL:AF056191 xref: EMBL:AF328769 xref: EMBL:AK074268 xref: EMBL:AK090465 xref: EMBL:BC007529 xref: EMBL:BC013985 xref: EMBL:CR456537 xref: EMBL:U80745 xref: HGNC:HGNC:14248 xref: UniGene:Hs.517421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005790 ! MED15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005060 name: MED16_human def: "Mediator of RNA polymerase II transcription subunit 16 gene" [UniProtKB:Q9Y2X0] synonym: "DRIP92" EXACT [UniProtKB:Q9Y2X0] synonym: "THRAP5" EXACT [UniProtKB:Q9Y2X0] xref: EMBL:AF106934 xref: EMBL:AF121228 xref: EMBL:BC004554 xref: EMBL:BC007853 xref: EMBL:BC011841 xref: EMBL:BC017282 xref: HGNC:HGNC:17556 xref: UniGene:Hs.365207 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005791 ! MED16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005061 name: MED17_human def: "Mediator of RNA polymerase II transcription subunit 17 gene" [UniProtKB:Q9NVC6] synonym: "ARC77" EXACT [UniProtKB:Q9NVC6] synonym: "CRSP6" EXACT [UniProtKB:Q9NVC6] synonym: "DRIP77" EXACT [UniProtKB:Q9NVC6] synonym: "DRIP80" EXACT [UniProtKB:Q9NVC6] synonym: "TRAP80" EXACT [UniProtKB:Q9NVC6] xref: EMBL:AF104254 xref: EMBL:AF105421 xref: EMBL:AF117657 xref: EMBL:AK001674 xref: EMBL:AK022156 xref: EMBL:BC021101 xref: HGNC:HGNC:2375 xref: UniGene:Hs.444931 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005785 ! MED17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005062 name: MED18_human def: "Mediator of RNA polymerase II transcription subunit 18 gene" [UniProtKB:Q9BUE0] xref: EMBL:AB107222 xref: EMBL:AK000052 xref: EMBL:AL353622 xref: EMBL:BC002694 xref: EMBL:CH471059 xref: HGNC:HGNC:25944 xref: UniGene:Hs.479911 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005787 ! MED18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005063 name: MED1_human def: "Mediator of RNA polymerase II transcription subunit 1 gene" [UniProtKB:Q15648] synonym: "ARC205" EXACT [UniProtKB:Q15648] synonym: "CRSP1" EXACT [UniProtKB:Q15648] synonym: "CRSP200" EXACT [UniProtKB:Q15648] synonym: "DRIP205" EXACT [UniProtKB:Q15648] synonym: "DRIP230" EXACT [UniProtKB:Q15648] synonym: "PBP" EXACT [UniProtKB:Q15648] synonym: "PPARBP" EXACT [UniProtKB:Q15648] synonym: "PPARGBP" EXACT [UniProtKB:Q15648] synonym: "RB18A" EXACT [UniProtKB:Q15648] synonym: "TRAP220" EXACT [UniProtKB:Q15648] synonym: "TRIP2" EXACT [UniProtKB:Q15648] xref: EMBL:AF055994 xref: EMBL:AF283812 xref: EMBL:BC006517 xref: EMBL:BC060758 xref: EMBL:BC131783 xref: EMBL:CH471152 xref: EMBL:L40366 xref: EMBL:Y13467 xref: HGNC:HGNC:9234 xref: UniGene:Hs.702009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005786 ! MED1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005064 name: MED20_human def: "Mediator of RNA polymerase II transcription subunit 20 gene" [UniProtKB:Q9H944] synonym: "TRFP" EXACT [UniProtKB:Q9H944] xref: EMBL:AF097725 xref: EMBL:AK023092 xref: EMBL:AL050196 xref: EMBL:AL160163 xref: EMBL:BC012618 xref: EMBL:BC019866 xref: EMBL:BC032552 xref: EMBL:BC040950 xref: HGNC:HGNC:16840 xref: UniGene:Hs.278434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005781 ! MED20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005065 name: MED21_human def: "Mediator of RNA polymerase II transcription subunit 21 gene" [UniProtKB:Q13503] synonym: "SRB7" EXACT [UniProtKB:Q13503] synonym: "SURB7" EXACT [UniProtKB:Q13503] xref: EMBL:BC008380 xref: EMBL:CR456999 xref: EMBL:U46837 xref: EMBL:U52960 xref: HGNC:HGNC:11473 xref: UniGene:Hs.286145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005783 ! MED21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005066 name: MED22_human def: "Mediator of RNA polymerase II transcription subunit 22 gene" [UniProtKB:Q15528] synonym: "SURF5" EXACT [UniProtKB:Q15528] xref: EMBL:AJ224358 xref: EMBL:AJ224359 xref: EMBL:AJ224639 xref: EMBL:AL158826 xref: EMBL:BC024225 xref: EMBL:BC040111 xref: EMBL:CH471090 xref: EMBL:X85178 xref: HGNC:HGNC:11477 xref: UniGene:Hs.78354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005795 ! MED22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005067 name: MED23_human def: "Mediator of RNA polymerase II transcription subunit 23 gene" [UniProtKB:Q9ULK4] synonym: "ARC130" EXACT [UniProtKB:Q9ULK4] synonym: "CRSP3" EXACT [UniProtKB:Q9ULK4] synonym: "DRIP130" EXACT [UniProtKB:Q9ULK4] synonym: "KIAA1216" EXACT [UniProtKB:Q9ULK4] synonym: "SUR2" EXACT [UniProtKB:Q9ULK4] xref: EMBL:AB033042 xref: EMBL:AF104255 xref: EMBL:AF105332 xref: EMBL:AF135022 xref: EMBL:AL121575 xref: EMBL:AL136776 xref: EMBL:BC060759 xref: EMBL:CH471051 xref: HGNC:HGNC:2372 xref: UniGene:Hs.29679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005793 ! MED23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005068 name: MED24_human def: "Mediator of RNA polymerase II transcription subunit 24 gene" [UniProtKB:O75448] synonym: "ARC100" EXACT [UniProtKB:O75448] synonym: "CRSP4" EXACT [UniProtKB:O75448] synonym: "DRIP100" EXACT [UniProtKB:O75448] synonym: "KIAA0130" EXACT [UniProtKB:O75448] synonym: "THRAP4" EXACT [UniProtKB:O75448] synonym: "TRAP100" EXACT [UniProtKB:O75448] xref: EMBL:AF055995 xref: EMBL:AF277379 xref: EMBL:BC011375 xref: EMBL:D50920 xref: HGNC:HGNC:22963 xref: UniGene:Hs.462983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005799 ! MED24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005069 name: MED26_human def: "Mediator of RNA polymerase II transcription subunit 26 gene" [UniProtKB:O95402] synonym: "ARC70" EXACT [UniProtKB:O95402] synonym: "CRSP7" EXACT [UniProtKB:O95402] xref: EMBL:AF104253 xref: EMBL:BC110430 xref: EMBL:BC127215 xref: HGNC:HGNC:2376 xref: UniGene:Hs.356467 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005575 ! MED26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005070 name: MED27_human def: "Mediator of RNA polymerase II transcription subunit 27 gene" [UniProtKB:Q6P2C8] synonym: "CRSP34" EXACT [UniProtKB:Q6P2C8] synonym: "CRSP8" EXACT [UniProtKB:Q6P2C8] xref: EMBL:AF104252 xref: EMBL:AF230382 xref: EMBL:AL160271 xref: EMBL:AL513102 xref: EMBL:AL603649 xref: EMBL:AL713892 xref: EMBL:BC002878 xref: EMBL:BC064608 xref: EMBL:DQ099387 xref: HGNC:HGNC:2377 xref: UniGene:Hs.374262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005780 ! MED27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005071 name: MED28_human def: "Mediator of RNA polymerase II transcription subunit 28 gene" [UniProtKB:Q9H204] synonym: "EG1" EXACT [UniProtKB:Q9H204] synonym: "FKSG20" EXACT [UniProtKB:Q9H204] xref: EMBL:AF317680 xref: EMBL:AF318059 xref: EMBL:AF321617 xref: EMBL:AF358829 xref: EMBL:BC011936 xref: HGNC:HGNC:24628 xref: UniGene:Hs.434075 xref: UniGene:Hs.644788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005468 ! MED28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005072 name: MED29_human def: "Mediator of RNA polymerase II transcription subunit 29 gene" [UniProtKB:Q9NX70] synonym: "IXL" EXACT [UniProtKB:Q9NX70] xref: EMBL:AK000411 xref: EMBL:AL137304 xref: EMBL:AY729650 xref: EMBL:BC019015 xref: HGNC:HGNC:23074 xref: UniGene:Hs.611541 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005574 ! MED29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005073 name: MED30_human def: "Mediator of RNA polymerase II transcription subunit 30 gene" [UniProtKB:Q96HR3] synonym: "THRAP6" EXACT [UniProtKB:Q96HR3] synonym: "TRAP25" EXACT [UniProtKB:Q96HR3] xref: EMBL:AY083305 xref: EMBL:BC008226 xref: HGNC:HGNC:23032 xref: UniGene:Hs.492612 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005797 ! MED30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005074 name: MED31_human def: "Mediator of RNA polymerase II transcription subunit 31 gene" [UniProtKB:Q9Y3C7] synonym: "CGI-125" EXACT [UniProtKB:Q9Y3C7] synonym: "SOH1" EXACT [UniProtKB:Q9Y3C7] xref: EMBL:AF151883 xref: EMBL:BC012539 xref: HGNC:HGNC:24260 xref: UniGene:Hs.567493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005784 ! MED31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005075 name: MED4_human def: "Mediator of RNA polymerase II transcription subunit 4 gene" [UniProtKB:Q9NPJ6] synonym: "ARC36" EXACT [UniProtKB:Q9NPJ6] synonym: "DRIP36" EXACT [UniProtKB:Q9NPJ6] synonym: "HSPC126" EXACT [UniProtKB:Q9NPJ6] synonym: "VDRIP" EXACT [UniProtKB:Q9NPJ6] xref: EMBL:AF161475 xref: EMBL:AF230381 xref: EMBL:AF300618 xref: EMBL:AK001934 xref: EMBL:AK222713 xref: EMBL:AK223017 xref: EMBL:AL158196 xref: EMBL:BC005189 xref: EMBL:CR457276 xref: EMBL:CR541830 xref: HGNC:HGNC:17903 xref: UniGene:Hs.181112 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005277 ! MED4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005076 name: MED6_human def: "Mediator of RNA polymerase II transcription subunit 6 gene" [UniProtKB:O75586] synonym: "ARC33" EXACT [UniProtKB:O75586] xref: EMBL:AF074723 xref: EMBL:AF155104 xref: EMBL:AK222587 xref: EMBL:AK223346 xref: EMBL:BC004106 xref: EMBL:BT006831 xref: EMBL:CR541697 xref: EMBL:U78082 xref: HGNC:HGNC:19970 xref: UniGene:Hs.497353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005792 ! MED6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005077 name: MED7_human def: "Mediator of RNA polymerase II transcription subunit 7 gene" [UniProtKB:O43513] synonym: "ARC34" EXACT [UniProtKB:O43513] synonym: "CRSP9" EXACT [UniProtKB:O43513] xref: EMBL:AF031383 xref: EMBL:AF104251 xref: EMBL:BC005250 xref: HGNC:HGNC:2378 xref: UniGene:Hs.279902 xref: UniGene:Hs.616365 xref: UniGene:Hs.696637 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005782 ! MED7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005078 name: MED8_human def: "Mediator of RNA polymerase II transcription subunit 8 gene" [UniProtKB:Q96G25] xref: EMBL:AF521562 xref: EMBL:AL139289 xref: EMBL:BC010019 xref: EMBL:BC010543 xref: EMBL:BG722466 xref: HGNC:HGNC:19971 xref: UniGene:Hs.301756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005798 ! MED8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005079 name: MED9_human def: "Mediator of RNA polymerase II transcription subunit 9 gene" [UniProtKB:Q9NWA0] synonym: "MED25" EXACT [UniProtKB:Q9NWA0] xref: EMBL:AK001055 xref: EMBL:BC104988 xref: EMBL:BC112029 xref: EMBL:CH471196 xref: HGNC:HGNC:25487 xref: UniGene:Hs.244595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005475 ! MED9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005080 name: MEGF10_human def: "Multiple epidermal growth factor-like domains 10 precursor gene" [UniProtKB:Q96KG7] synonym: "KIAA1780" EXACT [UniProtKB:Q96KG7] xref: EMBL:AB058676 xref: EMBL:BC020198 xref: EMBL:BC152478 xref: EMBL:CH471062 xref: EMBL:CR749437 xref: HGNC:HGNC:29634 xref: UniGene:Hs.438709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005549 ! MEG10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005081 name: MEGF6_human def: "Multiple epidermal growth factor-like domains 6 precursor gene" [UniProtKB:O75095] synonym: "EGFL3" EXACT [UniProtKB:O75095] synonym: "KIAA0815" EXACT [UniProtKB:O75095] xref: EMBL:AB011539 xref: EMBL:AL512413 xref: EMBL:AL513320 xref: HGNC:HGNC:3232 xref: UniGene:Hs.593645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005956 ! MEGF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005082 name: MEGF8_human def: "Multiple epidermal growth factor-like domains 8 gene" [UniProtKB:Q7Z7M0] synonym: "C19orf49" EXACT [UniProtKB:Q7Z7M0] synonym: "EGFL4" EXACT [UniProtKB:Q7Z7M0] synonym: "KIAA0817" EXACT [UniProtKB:Q7Z7M0] xref: EMBL:AB011541 xref: EMBL:AY280362 xref: HGNC:HGNC:3233 xref: UniGene:Hs.132483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005957 ! MEGF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005083 name: MEOX2_human def: "Homeobox protein MOX-2 gene" [UniProtKB:P50222] synonym: "GAX" EXACT [UniProtKB:P50222] synonym: "MOX2" EXACT [UniProtKB:P50222] xref: EMBL:AC004452 xref: EMBL:AC005550 xref: EMBL:BC017021 xref: EMBL:L36328 xref: EMBL:X82629 xref: HGNC:HGNC:7014 xref: UniGene:Hs.170355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005623 ! MEOX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005084 name: THOP1_human def: "Thimet oligopeptidase gene" [UniProtKB:P52888] xref: EMBL:AC006538 xref: EMBL:BC000135 xref: EMBL:BC002391 xref: EMBL:U29366 xref: EMBL:Z50115 xref: HGNC:HGNC:11793 xref: UniGene:Hs.78769 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035951 ! THOP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005085 name: NF2_human def: "Merlin gene" [UniProtKB:P35240] synonym: "SCH" EXACT [UniProtKB:P35240] xref: EMBL:AF122827 xref: EMBL:AF122828 xref: EMBL:AF123570 xref: EMBL:AF369657 xref: EMBL:AF369658 xref: EMBL:AF369661 xref: EMBL:AF369662 xref: EMBL:AF369663 xref: EMBL:AF369664 xref: EMBL:AF369665 xref: EMBL:AF369700 xref: EMBL:AF369701 xref: EMBL:BC003112 xref: EMBL:BC020257 xref: EMBL:CR456530 xref: EMBL:L11353 xref: EMBL:X72655 xref: EMBL:X72656 xref: EMBL:X72657 xref: EMBL:X72658 xref: EMBL:X72659 xref: EMBL:X72660 xref: EMBL:X72661 xref: EMBL:X72662 xref: EMBL:X72663 xref: EMBL:X72664 xref: EMBL:X72665 xref: EMBL:X72666 xref: EMBL:X72667 xref: EMBL:X72668 xref: EMBL:X72669 xref: EMBL:X72670 xref: EMBL:Y18000 xref: EMBL:Z22664 xref: HGNC:HGNC:7773 xref: UniGene:Hs.187898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001592 ! MERL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005086 name: MET_human def: "Hepatocyte growth factor receptor precursor gene" [UniProtKB:P08581] xref: EMBL:AC002080 xref: EMBL:AC002543 xref: EMBL:AC004416 xref: EMBL:J02958 xref: EMBL:M35074 xref: EMBL:U08818 xref: EMBL:X54559 xref: HGNC:HGNC:7029 xref: UniGene:Hs.132966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005438 ! MET_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005087 name: SPEN_human def: "Msx2-interacting protein gene" [UniProtKB:Q96T58] synonym: "KIAA0929" EXACT [UniProtKB:Q96T58] synonym: "MINT" EXACT [UniProtKB:Q96T58] synonym: "SHARP" EXACT [UniProtKB:Q96T58] xref: EMBL:AB023146 xref: EMBL:AF356524 xref: EMBL:AK000882 xref: EMBL:AK022949 xref: EMBL:AL034555 xref: EMBL:AL096858 xref: EMBL:AL450998 xref: HGNC:HGNC:17575 xref: UniGene:Hs.558463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006042 ! MINT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005088 name: MIS12_human def: "Protein MIS12 homolog gene" [UniProtKB:Q9H081] xref: EMBL:AK056072 xref: EMBL:AL136906 xref: EMBL:BC000229 xref: EMBL:CR533460 xref: HGNC:HGNC:24967 xref: UniGene:Hs.267194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002122 ! MIS12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005089 name: MAPK1_human def: "Mitogen-activated protein kinase 1 gene" [UniProtKB:P28482] synonym: "ERK2" EXACT [UniProtKB:P28482] synonym: "PRKM1" EXACT [UniProtKB:P28482] synonym: "PRKM2" EXACT [UniProtKB:P28482] xref: EMBL:BC017832 xref: EMBL:M84489 xref: EMBL:Z11694 xref: EMBL:Z11695 xref: HGNC:HGNC:6871 xref: UniGene:Hs.431850 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001565 ! MK01_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005090 name: MAPK3_human def: "Mitogen-activated protein kinase 3 gene" [UniProtKB:P27361] synonym: "ERK1" EXACT [UniProtKB:P27361] synonym: "PRKM3" EXACT [UniProtKB:P27361] xref: EMBL:BC013992 xref: EMBL:M84490 xref: EMBL:X60188 xref: EMBL:Z11696 xref: HGNC:HGNC:6877 xref: UniGene:Hs.861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001560 ! MK03_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005091 name: MAPK4_human def: "Mitogen-activated protein kinase 4 gene" [UniProtKB:P31152] synonym: "ERK4" EXACT [UniProtKB:P31152] synonym: "PRKM4" EXACT [UniProtKB:P31152] xref: EMBL:AC012433 xref: EMBL:AC090395 xref: EMBL:AK295058 xref: EMBL:X59727 xref: HGNC:HGNC:6878 xref: UniGene:Hs.433728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001582 ! MK04_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005092 name: MAPK6_human def: "Mitogen-activated protein kinase 6 gene" [UniProtKB:Q16659] synonym: "ERK3" EXACT [UniProtKB:Q16659] synonym: "PRKM6" EXACT [UniProtKB:Q16659] xref: EMBL:AF420474 xref: EMBL:BC035492 xref: EMBL:CR749401 xref: EMBL:L77964 xref: EMBL:X80692 xref: HGNC:HGNC:6879 xref: UniGene:Hs.411847 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001822 ! MK06_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005093 name: MAPK8_human def: "Mitogen-activated protein kinase 8 gene" [UniProtKB:P45983] synonym: "JNK1" EXACT [UniProtKB:P45983] synonym: "PRKM8" EXACT [UniProtKB:P45983] xref: EMBL:L26318 xref: EMBL:U34822 xref: EMBL:U35004 xref: EMBL:U35005 xref: HGNC:HGNC:6881 xref: UniGene:Hs.138211 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005638 ! MK08_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005094 name: MAPK11_human def: "Mitogen-activated protein kinase 11 gene" [UniProtKB:Q15759] synonym: "PRKM11" EXACT [UniProtKB:Q15759] synonym: "SAPK2" EXACT [UniProtKB:Q15759] xref: EMBL:AF001008 xref: EMBL:AF001174 xref: EMBL:AF031135 xref: EMBL:AL022328 xref: EMBL:BC027933 xref: EMBL:CR456514 xref: EMBL:DQ279722 xref: EMBL:U53442 xref: EMBL:U92268 xref: EMBL:Y14440 xref: HGNC:HGNC:6873 xref: UniGene:Hs.57732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005892 ! MK11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005095 name: MAPK12_human def: "Mitogen-activated protein kinase 12 gene" [UniProtKB:P53778] synonym: "ERK6" EXACT [UniProtKB:P53778] synonym: "SAPK3" EXACT [UniProtKB:P53778] xref: EMBL:AL022328 xref: EMBL:BC015741 xref: EMBL:U66243 xref: EMBL:X79483 xref: EMBL:Y10487 xref: HGNC:HGNC:6874 xref: UniGene:Hs.432642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001665 ! MK12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005096 name: MAPK13_human def: "Mitogen-activated protein kinase 13 gene" [UniProtKB:O15264] synonym: "PRKM13" EXACT [UniProtKB:O15264] synonym: "SAPK4" EXACT [UniProtKB:O15264] xref: EMBL:AF004709 xref: EMBL:AF015256 xref: EMBL:AF092535 xref: EMBL:AF100546 xref: EMBL:BC000433 xref: EMBL:BC001641 xref: EMBL:BC004428 xref: EMBL:BT007221 xref: EMBL:U93232 xref: EMBL:Y10488 xref: EMBL:Z95152 xref: HGNC:HGNC:6875 xref: UniGene:Hs.178695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001369 ! MK13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005097 name: MKKS_human def: "McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin gene" [UniProtKB:Q9NPJ1] xref: EMBL:AF221992 xref: EMBL:AF221993 xref: EMBL:AL034430 xref: EMBL:AL157427 xref: HGNC:HGNC:7108 xref: UniGene:Hs.472119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006284 ! MKKS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005098 name: MDK_human def: "Midkine precursor gene" [UniProtKB:P21741] synonym: "MK1" EXACT [UniProtKB:P21741] synonym: "NEGF2" EXACT [UniProtKB:P21741] xref: EMBL:BC011704 xref: EMBL:D10604 xref: EMBL:M69148 xref: EMBL:M94250 xref: EMBL:X55110 xref: HGNC:HGNC:6972 xref: UniGene:Hs.82045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001544 ! MK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005099 name: MLF1_human def: "Myeloid leukemia factor 1 gene" [UniProtKB:P58340] xref: EMBL:BC007045 xref: EMBL:L49054 xref: HGNC:HGNC:7125 xref: UniGene:Hs.85195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001684 ! MLF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005100 name: MLH1_human def: "DNA mismatch repair protein Mlh1 gene" [UniProtKB:P40692] synonym: "COCA2" EXACT [UniProtKB:P40692] xref: EMBL:AY217549 xref: EMBL:BC006850 xref: EMBL:DQ648889 xref: EMBL:DQ648891 xref: EMBL:DQ648892 xref: EMBL:EU188671 xref: EMBL:EU188674 xref: EMBL:U07343 xref: EMBL:U07418 xref: EMBL:U17839 xref: EMBL:U17840 xref: EMBL:U17841 xref: EMBL:U17842 xref: EMBL:U17843 xref: EMBL:U17844 xref: EMBL:U17845 xref: EMBL:U17846 xref: EMBL:U17847 xref: EMBL:U17848 xref: EMBL:U17849 xref: EMBL:U17851 xref: EMBL:U17852 xref: EMBL:U17853 xref: EMBL:U17854 xref: EMBL:U17855 xref: EMBL:U17856 xref: EMBL:U17857 xref: EMBL:U40960 xref: EMBL:U40961 xref: EMBL:U40962 xref: EMBL:U40963 xref: EMBL:U40964 xref: EMBL:U40965 xref: EMBL:U40966 xref: EMBL:U40967 xref: EMBL:U40968 xref: EMBL:U40969 xref: EMBL:U40970 xref: EMBL:U40971 xref: EMBL:U40972 xref: EMBL:U40973 xref: EMBL:U40974 xref: EMBL:U40975 xref: EMBL:U40976 xref: EMBL:U40977 xref: EMBL:U40978 xref: HGNC:HGNC:7127 xref: UniGene:Hs.195364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001601 ! MLH1_HUMAN relationship: codes_for CCO:B0024428 ! Q0ZAJ5_HUMAN relationship: codes_for CCO:B0032066 ! A8W2K5_HUMAN relationship: codes_for CCO:B0054147 ! A8W2L5_HUMAN relationship: codes_for CCO:B0055831 ! Q0ZAJ4_HUMAN relationship: codes_for CCO:B0055832 ! Q0ZAJ7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005101 name: MLH3_human def: "DNA mismatch repair protein Mlh3 gene" [UniProtKB:Q9UHC1] xref: EMBL:AB039667 xref: EMBL:AF195657 xref: EMBL:AF195658 xref: EMBL:AY963685 xref: EMBL:L40399 xref: HGNC:HGNC:7128 xref: UniGene:Hs.436650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002200 ! MLH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005102 name: MAP1LC3A_human def: "Microtubule-associated proteins 1A/1B light chain 3A precursor gene" [UniProtKB:Q9H492] xref: EMBL:AF276658 xref: EMBL:AL118520 xref: EMBL:AL833855 xref: EMBL:BC015810 xref: EMBL:BT007452 xref: HGNC:HGNC:6838 xref: UniGene:Hs.632273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006281 ! MLP3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005103 name: MAP1LC3B_human def: "Microtubule-associated proteins 1A/1B light chain 3B precursor gene" [UniProtKB:Q9GZQ8] synonym: "MAP1ALC3" EXACT [UniProtKB:Q9GZQ8] xref: EMBL:AF087871 xref: EMBL:AF183417 xref: EMBL:AF303888 xref: EMBL:AK025556 xref: EMBL:BC018634 xref: EMBL:BC041874 xref: EMBL:BC067797 xref: HGNC:HGNC:13352 xref: UniGene:Hs.356061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006342 ! MLP3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005105 name: MLTK_human def: "Mitogen-activated protein kinase kinase kinase MLT gene" [UniProtKB:Q9NYL2] synonym: "HCCS4" EXACT [UniProtKB:Q9NYL2] synonym: "ZAK" EXACT [UniProtKB:Q9NYL2] xref: EMBL:AB030034 xref: EMBL:AB049733 xref: EMBL:AB049734 xref: EMBL:AB208974 xref: EMBL:AC013461 xref: EMBL:AC019046 xref: EMBL:AC092573 xref: EMBL:AF238255 xref: EMBL:AF251441 xref: EMBL:AF325454 xref: EMBL:AF465843 xref: EMBL:AF480461 xref: EMBL:AF480462 xref: EMBL:BC001401 xref: UniGene:Hs.444451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002178 ! MLTK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005106 name: MNS1_human def: "Meiosis-specific nuclear structural protein 1 gene" [UniProtKB:Q8NEH6] xref: EMBL:AK002084 xref: EMBL:BC031046 xref: EMBL:BC034991 xref: HGNC:HGNC:29636 xref: UniGene:Hs.444483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001979 ! MNS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005107 name: MNT_human def: "Max-binding protein MNT gene" [UniProtKB:Q99583] synonym: "ROX" EXACT [UniProtKB:Q99583] xref: EMBL:BC117563 xref: EMBL:X96401 xref: EMBL:Y13440 xref: EMBL:Y13441 xref: EMBL:Y13442 xref: EMBL:Y13443 xref: EMBL:Y13444 xref: HGNC:HGNC:7188 xref: UniGene:Hs.626579 xref: UniGene:Hs.632239 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002074 ! MNT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005108 name: MORF4L1_human def: "Mortality factor 4-like protein 1 gene" [UniProtKB:Q9UBU8] synonym: "FWP006" EXACT [UniProtKB:Q9UBU8] synonym: "HSPC008" EXACT [UniProtKB:Q9UBU8] synonym: "HSPC061" EXACT [UniProtKB:Q9UBU8] synonym: "MRG15" EXACT [UniProtKB:Q9UBU8] synonym: "PP368" EXACT [UniProtKB:Q9UBU8] xref: EMBL:AF070664 xref: EMBL:AF100615 xref: EMBL:AF109188 xref: EMBL:AF131847 xref: EMBL:AF161546 xref: EMBL:AF167173 xref: EMBL:AF218011 xref: EMBL:AL137697 xref: EMBL:AY148481 xref: EMBL:BC002936 xref: EMBL:BC022845 xref: EMBL:BC067826 xref: HGNC:HGNC:16989 xref: UniGene:Hs.374503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005917 ! MO4L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005109 name: MORF4L2_human def: "Mortality factor 4-like protein 2 gene" [UniProtKB:Q15014] synonym: "KIAA0026" EXACT [UniProtKB:Q15014] synonym: "MRGX" EXACT [UniProtKB:Q15014] xref: EMBL:AB050778 xref: EMBL:AF100620 xref: EMBL:AF167174 xref: EMBL:AL049610 xref: EMBL:BC056899 xref: EMBL:BC093013 xref: EMBL:D14812 xref: HGNC:HGNC:16849 xref: UniGene:Hs.326387 xref: UniGene:Hs.597035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005370 ! MO4L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005111 name: MON1A_human def: "Vacuolar fusion protein MON1 homolog A gene" [UniProtKB:Q86VX9] synonym: "SAND1" EXACT [UniProtKB:Q86VX9] xref: EMBL:AK092018 xref: EMBL:BC006299 xref: EMBL:BC009459 xref: EMBL:BC047022 xref: HGNC:HGNC:28207 xref: UniGene:Hs.655014 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005970 ! MON1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005113 name: MAP2K1_human def: "Dual specificity mitogen-activated protein kinase kinase 1 gene" [UniProtKB:Q02750] synonym: "MEK1" EXACT [UniProtKB:Q02750] synonym: "PRKMK1" EXACT [UniProtKB:Q02750] xref: EMBL:L05624 xref: EMBL:L11284 xref: HGNC:HGNC:6840 xref: UniGene:Hs.145442 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001718 ! MP2K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005114 name: MAP2K6_human def: "Dual specificity mitogen-activated protein kinase kinase 6 gene" [UniProtKB:P52564] synonym: "MEK6" EXACT [UniProtKB:P52564] synonym: "MKK6" EXACT [UniProtKB:P52564] synonym: "PRKMK6" EXACT [UniProtKB:P52564] xref: EMBL:BC012009 xref: EMBL:D87905 xref: EMBL:U39064 xref: EMBL:U39065 xref: EMBL:U39656 xref: EMBL:U39657 xref: EMBL:U49732 xref: EMBL:X96757 xref: HGNC:HGNC:6846 xref: UniGene:Hs.463978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001658 ! MP2K6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005115 name: SLC25A3_human def: "Phosphate carrier protein, mitochondrial precursor gene" [UniProtKB:Q00325] synonym: "OK/SW-cl.48" EXACT [UniProtKB:Q00325] synonym: "PHC" EXACT [UniProtKB:Q00325] xref: EMBL:AB064666 xref: EMBL:BC000998 xref: EMBL:BC001328 xref: EMBL:BC003504 xref: EMBL:BC004345 xref: EMBL:BC006455 xref: EMBL:BC011574 xref: EMBL:BC011641 xref: EMBL:BC014019 xref: EMBL:BC015379 xref: EMBL:X60036 xref: EMBL:X77337 xref: HGNC:HGNC:10989 xref: UniGene:Hs.290404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005847 ! MPCP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005116 name: MPHOSPH6_human def: "M-phase phosphoprotein 6 gene" [UniProtKB:Q99547] synonym: "MPP6" EXACT [UniProtKB:Q99547] xref: EMBL:BC005242 xref: EMBL:BC011020 xref: EMBL:BC031017 xref: EMBL:X98263 xref: HGNC:HGNC:7214 xref: UniGene:Hs.344400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002071 ! MPH6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005117 name: CDC25A_human def: "M-phase inducer phosphatase 1 gene" [UniProtKB:P30304] xref: EMBL:AF277722 xref: EMBL:AF527417 xref: EMBL:AY137580 xref: EMBL:BC007401 xref: EMBL:BC018642 xref: EMBL:M81933 xref: HGNC:HGNC:1725 xref: UniGene:Hs.437705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001576 ! MPIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005118 name: CDC25B_human def: "M-phase inducer phosphatase 2 gene" [UniProtKB:P30305] synonym: "CDC25HU2" EXACT [UniProtKB:P30305] xref: EMBL:AF036233 xref: EMBL:AL109804 xref: EMBL:AY494082 xref: EMBL:BC006395 xref: EMBL:BC009953 xref: EMBL:BC051711 xref: EMBL:M81934 xref: EMBL:S78187 xref: EMBL:X96436 xref: EMBL:Z68092 xref: HGNC:HGNC:1726 xref: UniGene:Hs.153752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001393 ! O43550_HUMAN relationship: codes_for CCO:B0001577 ! MPIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005119 name: CDC25C_human def: "M-phase inducer phosphatase 3 gene" [UniProtKB:P30307] xref: EMBL:AF277723 xref: EMBL:AF277724 xref: EMBL:AF277725 xref: EMBL:AF277726 xref: EMBL:AF312681 xref: EMBL:AJ304504 xref: EMBL:AY497474 xref: EMBL:BC019089 xref: EMBL:M34065 xref: HGNC:HGNC:1727 xref: UniGene:Hs.656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001578 ! MPIP3_HUMAN relationship: codes_for CCO:B0002127 ! Q9H2F0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005120 name: MPP3_human def: "MAGUK p55 subfamily member 3 gene" [UniProtKB:Q13368] synonym: "DLG3" EXACT [UniProtKB:Q13368] xref: EMBL:AM050144 xref: EMBL:AM050145 xref: EMBL:BC047017 xref: EMBL:BC056865 xref: EMBL:U37707 xref: HGNC:HGNC:7221 xref: UniGene:Hs.396566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006207 ! MPP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005121 name: MPHOSPH8_human def: "M-phase phosphoprotein 8 gene" [UniProtKB:Q99549] synonym: "MPP8" EXACT [UniProtKB:Q99549] xref: EMBL:AK056785 xref: EMBL:AL354808 xref: EMBL:AL359457 xref: EMBL:AL832864 xref: EMBL:BC003542 xref: EMBL:BC046214 xref: EMBL:CH471075 xref: EMBL:X98259 xref: HGNC:HGNC:29810 xref: UniGene:Hs.269654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002072 ! MPP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005123 name: MPHOSPH1_human def: "M-phase phosphoprotein 1 gene" [UniProtKB:Q96Q89] synonym: "KRMP1" EXACT [UniProtKB:Q96Q89] xref: EMBL:AB033337 xref: EMBL:AB033338 xref: EMBL:AK024959 xref: EMBL:AK025628 xref: EMBL:AL117496 xref: EMBL:AL137392 xref: EMBL:AL157389 xref: EMBL:AL157400 xref: EMBL:AY282406 xref: EMBL:AY282407 xref: EMBL:AY739715 xref: EMBL:BC012585 xref: EMBL:BC046134 xref: EMBL:BC058913 xref: EMBL:BC093089 xref: EMBL:BC108688 xref: EMBL:L16782 xref: EMBL:U93121 xref: HGNC:HGNC:7212 xref: UniGene:Hs.240 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002056 ! MPPH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005124 name: MRE11A_human def: "Double-strand break repair protein MRE11A gene" [UniProtKB:P49959] synonym: "HNGS1" EXACT [UniProtKB:P49959] synonym: "MRE11" EXACT [UniProtKB:P49959] xref: EMBL:AF022778 xref: EMBL:AF073362 xref: EMBL:AF303379 xref: EMBL:AF303380 xref: EMBL:AF303381 xref: EMBL:AF303382 xref: EMBL:AF303383 xref: EMBL:AF303384 xref: EMBL:AF303385 xref: EMBL:AF303386 xref: EMBL:AF303387 xref: EMBL:AF303388 xref: EMBL:AF303389 xref: EMBL:AF303390 xref: EMBL:AF303391 xref: EMBL:AF303392 xref: EMBL:AF303393 xref: EMBL:AF303394 xref: EMBL:AF303395 xref: EMBL:AY584241 xref: EMBL:BC063458 xref: EMBL:U37359 xref: HGNC:HGNC:7230 xref: UniGene:Hs.192649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001641 ! MRE11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005125 name: MRGBP_human def: "MRG-binding protein gene" [UniProtKB:Q9NV56] synonym: "C20orf20" EXACT [UniProtKB:Q9NV56] xref: EMBL:AK001776 xref: EMBL:AL035669 xref: EMBL:BC009889 xref: EMBL:BC014235 xref: EMBL:BC018841 xref: HGNC:HGNC:15866 xref: UniGene:Hs.590870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005360 ! MRGBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005126 name: MSH2_human def: "DNA mismatch repair protein Msh2 gene" [UniProtKB:P43246] xref: EMBL:AF066081 xref: EMBL:AY601851 xref: EMBL:BC021566 xref: EMBL:DQ648894 xref: EMBL:DQ648895 xref: EMBL:DQ648896 xref: EMBL:L47581 xref: EMBL:L47582 xref: EMBL:L47583 xref: EMBL:U03911 xref: EMBL:U04045 xref: EMBL:U41206 xref: EMBL:U41207 xref: EMBL:U41208 xref: EMBL:U41210 xref: EMBL:U41211 xref: EMBL:U41212 xref: EMBL:U41213 xref: EMBL:U41214 xref: EMBL:U41215 xref: EMBL:U41216 xref: EMBL:U41217 xref: EMBL:U41218 xref: EMBL:U41219 xref: EMBL:U41220 xref: EMBL:U41221 xref: HGNC:HGNC:7325 xref: UniGene:Hs.597656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001620 ! MSH2_HUMAN relationship: codes_for CCO:B0055828 ! Q0ZAJ0_HUMAN relationship: codes_for CCO:B0055829 ! Q0ZAJ1_HUMAN relationship: codes_for CCO:B0055830 ! Q0ZAJ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005127 name: MSH3_human def: "DNA mismatch repair protein Msh3 gene" [UniProtKB:P20585] synonym: "DUC1" EXACT [UniProtKB:P20585] synonym: "DUG" EXACT [UniProtKB:P20585] xref: EMBL:AC008434 xref: EMBL:AY275681 xref: EMBL:BC011817 xref: EMBL:D61419 xref: EMBL:J04810 xref: EMBL:U61981 xref: HGNC:HGNC:7326 xref: UniGene:Hs.280987 xref: UniGene:Hs.648635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005720 ! MSH3_HUMAN relationship: codes_for CCO:B0017727 ! A6NMM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005128 name: MSH4_human def: "MutS protein homolog 4 gene" [UniProtKB:O15457] xref: EMBL:AF104243 xref: EMBL:AY268350 xref: EMBL:BC033030 xref: EMBL:U89293 xref: HGNC:HGNC:7327 xref: UniGene:Hs.216639 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001378 ! MSH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005129 name: MSH5_human def: "MutS protein homolog 5 gene" [UniProtKB:O43196] xref: EMBL:AF034759 xref: EMBL:AF048986 xref: EMBL:AF048988 xref: EMBL:AF048989 xref: EMBL:AF048990 xref: EMBL:AF048991 xref: EMBL:AF070071 xref: EMBL:AF070072 xref: EMBL:AF070073 xref: EMBL:AF070074 xref: EMBL:AF070075 xref: EMBL:AF070076 xref: EMBL:AF070077 xref: EMBL:AF070078 xref: EMBL:AF070079 xref: EMBL:AF129756 xref: EMBL:AF134726 xref: EMBL:AK097233 xref: EMBL:AL662834 xref: EMBL:AL662899 xref: EMBL:AL844216 xref: EMBL:AY943816 xref: EMBL:BA000025 xref: EMBL:BC001358 xref: EMBL:BC002498 xref: EMBL:BC041031 xref: EMBL:BT007200 xref: EMBL:BX248133 xref: EMBL:CR354443 xref: EMBL:CR759787 xref: EMBL:CR759915 xref: EMBL:CR925765 xref: EMBL:CR936239 xref: HGNC:HGNC:7328 xref: UniGene:Hs.371225 xref: UniGene:Hs.647011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001381 ! MSH5_HUMAN relationship: codes_for CCO:B0024896 ! A3KGN0_HUMAN relationship: codes_for CCO:B0024897 ! A2ABE9_HUMAN relationship: codes_for CCO:B0024899 ! A3KGM9_HUMAN relationship: codes_for CCO:B0024900 ! A2BEX2_HUMAN relationship: codes_for CCO:B0024901 ! A3KGM6_HUMAN relationship: codes_for CCO:B0024902 ! Q5SSR2_HUMAN relationship: codes_for CCO:B0024905 ! A2BEX3_HUMAN relationship: codes_for CCO:B0024906 ! A2ABF0_HUMAN relationship: codes_for CCO:B0024907 ! A2BEX4_HUMAN relationship: codes_for CCO:B0024909 ! A3KGM5_HUMAN relationship: codes_for CCO:B0024910 ! Q5SSQ8_HUMAN relationship: codes_for CCO:B0024911 ! A2BEX1_HUMAN relationship: codes_for CCO:B0024912 ! A3KGM4_HUMAN relationship: codes_for CCO:B0024914 ! A3KGM7_HUMAN relationship: codes_for CCO:B0042401 ! B0V0L9_HUMAN relationship: codes_for CCO:B0042404 ! B0UXD5_HUMAN relationship: codes_for CCO:B0053721 ! A2ABF1_HUMAN relationship: codes_for CCO:B0053743 ! A3KGN1_HUMAN relationship: codes_for CCO:B0053744 ! A3KGN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005130 name: MSH6_human def: "DNA mismatch repair protein Msh6 gene" [UniProtKB:P52701] synonym: "GTBP" EXACT [UniProtKB:P52701] xref: EMBL:AY082894 xref: EMBL:BC004246 xref: EMBL:D89645 xref: EMBL:D89646 xref: EMBL:U28946 xref: EMBL:U54777 xref: EMBL:U73732 xref: EMBL:U73733 xref: EMBL:U73734 xref: EMBL:U73736 xref: EMBL:U73737 xref: HGNC:HGNC:7329 xref: UniGene:Hs.445052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005639 ! MSH6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005131 name: MTCP1_human def: "Protein p8 MTCP-1 gene" [UniProtKB:P56277] synonym: "C6.1B" EXACT [UniProtKB:P56277] xref: EMBL:BC002600 xref: EMBL:BT006749 xref: EMBL:BX470111 xref: EMBL:CH471172 xref: EMBL:Z24459 xref: HGNC:HGNC:7423 xref: UniGene:Hs.6917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001677 ! MTCPA_HUMAN relationship: codes_for CCO:B0001678 ! MTCPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005132 name: MTFR1_human def: "Mitochondrial fission regulator 1 gene" [UniProtKB:Q15390] synonym: "CHPPR" EXACT [UniProtKB:Q15390] synonym: "KIAA0009" EXACT [UniProtKB:Q15390] xref: EMBL:BC036116 xref: EMBL:BC043498 xref: EMBL:CR456910 xref: EMBL:D13634 xref: HGNC:HGNC:29510 xref: UniGene:Hs.654531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006321 ! MTFR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005133 name: MTMR6_human def: "Myotubularin-related protein 6 gene" [UniProtKB:Q9Y217] xref: EMBL:AF072928 xref: EMBL:AF406619 xref: EMBL:AL590787 xref: EMBL:AL832017 xref: EMBL:BC040012 xref: HGNC:HGNC:7453 xref: UniGene:Hs.643702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006052 ! MTMR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005134 name: MTNR1A_human def: "Melatonin receptor type 1A gene" [UniProtKB:P48039] xref: EMBL:AB029933 xref: EMBL:BC074946 xref: EMBL:BC074947 xref: EMBL:BC126297 xref: EMBL:BC126299 xref: EMBL:U14108 xref: HGNC:HGNC:7463 xref: UniGene:Hs.243467 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005723 ! MTR1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005135 name: MTNR1B_human def: "Melatonin receptor type 1B gene" [UniProtKB:P49286] xref: EMBL:AB033598 xref: EMBL:AY521019 xref: EMBL:BC069163 xref: EMBL:U25341 xref: HGNC:HGNC:7464 xref: UniGene:Hs.569039 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005724 ! MTR1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005136 name: MTSS1_human def: "Metastasis suppressor protein 1 gene" [UniProtKB:O43312] synonym: "KIAA0429" EXACT [UniProtKB:O43312] synonym: "MIM" EXACT [UniProtKB:O43312] xref: EMBL:AB007889 xref: EMBL:AF086645 xref: EMBL:AK027015 xref: EMBL:BC023998 xref: HGNC:HGNC:20443 xref: UniGene:Hs.336994 xref: UniGene:Hs.700429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001390 ! MTSS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005137 name: MTUS1_human def: "Mitochondrial tumor suppressor 1 gene" [UniProtKB:Q9ULD2] synonym: "ATIP" EXACT [UniProtKB:Q9ULD2] synonym: "GK1" EXACT [UniProtKB:Q9ULD2] synonym: "KIAA1288" EXACT [UniProtKB:Q9ULD2] synonym: "MTSG1" EXACT [UniProtKB:Q9ULD2] xref: EMBL:AB033114 xref: EMBL:AF121259 xref: EMBL:AF293357 xref: EMBL:AK024357 xref: EMBL:AK125188 xref: EMBL:AL096842 xref: EMBL:AY363099 xref: EMBL:BC007328 xref: EMBL:BC033842 xref: EMBL:BC142971 xref: EMBL:BX648879 xref: HGNC:HGNC:29789 xref: UniGene:Hs.7946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002224 ! MTUS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005138 name: MUTYH_human def: "A/G-specific adenine DNA glycosylase gene" [UniProtKB:Q9UIF7] synonym: "MYH" EXACT [UniProtKB:Q9UIF7] xref: EMBL:AB032920 xref: EMBL:AB032921 xref: EMBL:AB032922 xref: EMBL:AB032923 xref: EMBL:AB032924 xref: EMBL:AB032925 xref: EMBL:AB032926 xref: EMBL:AB032927 xref: EMBL:AB032928 xref: EMBL:AB032929 xref: EMBL:AF527839 xref: EMBL:AL359540 xref: EMBL:BC003178 xref: EMBL:U63329 xref: HGNC:HGNC:7527 xref: UniGene:Hs.271353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002205 ! MUTYH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005139 name: MYBL2_human def: "Myb-related protein B gene" [UniProtKB:P10244] synonym: "BMYB" EXACT [UniProtKB:P10244] xref: EMBL:AL121886 xref: EMBL:BC007585 xref: EMBL:BC053555 xref: EMBL:X13293 xref: HGNC:HGNC:7548 xref: UniGene:Hs.179718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001505 ! MYBB_HUMAN relationship: codes_for CCO:B0028526 ! A8MXH7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005140 name: MYB_human def: "Myb proto-oncogene protein gene" [UniProtKB:P10242] xref: EMBL:AF104863 xref: EMBL:AL023693 xref: EMBL:BC064955 xref: EMBL:M13665 xref: EMBL:M13666 xref: EMBL:M15024 xref: EMBL:U22376 xref: EMBL:X17469 xref: EMBL:X52125 xref: HGNC:HGNC:7545 xref: UniGene:Hs.654446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005632 ! MYB_HUMAN relationship: codes_for CCO:B0028530 ! Q5THS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005141 name: MYCBP_human def: "C-Myc-binding protein gene" [UniProtKB:Q99417] synonym: "AMY1" EXACT [UniProtKB:Q99417] xref: EMBL:AB007191 xref: EMBL:AL139260 xref: EMBL:BC008686 xref: EMBL:BT007109 xref: EMBL:D50692 xref: HGNC:HGNC:7554 xref: UniGene:Hs.591506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006209 ! MYCBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005142 name: MYC_human def: "Myc proto-oncogene protein gene" [UniProtKB:P01106] xref: EMBL:AC103819 xref: EMBL:AY214166 xref: EMBL:BC000141 xref: EMBL:BC000917 xref: EMBL:BC058901 xref: EMBL:BT019768 xref: EMBL:CH471060 xref: EMBL:D10493 xref: EMBL:K00534 xref: EMBL:K00535 xref: EMBL:K01905 xref: EMBL:K01906 xref: EMBL:K02276 xref: EMBL:L00057 xref: EMBL:L00058 xref: EMBL:M13211 xref: EMBL:M13929 xref: EMBL:M20605 xref: EMBL:V00568 xref: EMBL:X00196 xref: EMBL:X00198 xref: EMBL:X00364 xref: EMBL:X00676 xref: HGNC:HGNC:7553 xref: UniGene:Hs.202453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001465 ! MYC_HUMAN relationship: codes_for CCO:B0021755 ! A0N2G3_HUMAN relationship: codes_for CCO:B0028295 ! A8MSJ8_HUMAN relationship: codes_for CCO:B0056024 ! Q14901_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005143 name: MYH14_human def: "Myosin-14 gene" [UniProtKB:Q7Z406] synonym: "FP17425" EXACT [UniProtKB:Q7Z406] synonym: "KIAA2034" EXACT [UniProtKB:Q7Z406] xref: EMBL:AB111886 xref: EMBL:AK023943 xref: EMBL:AY165122 xref: EMBL:AY203926 xref: EMBL:BC000676 xref: EMBL:BC004396 xref: EMBL:BC007877 xref: EMBL:BC018933 xref: EMBL:CR936653 xref: HGNC:HGNC:23212 xref: UniGene:Hs.467142 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005971 ! MYH14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005144 name: MYL6_human def: "Myosin light polypeptide 6 gene" [UniProtKB:P60660] xref: EMBL:AB046613 xref: EMBL:BC006781 xref: EMBL:BC017455 xref: EMBL:BC071661 xref: EMBL:CR457014 xref: EMBL:M22918 xref: EMBL:M22919 xref: EMBL:M22920 xref: EMBL:M31212 xref: EMBL:U02629 xref: HGNC:HGNC:7587 xref: UniGene:Hs.632717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005743 ! MYL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005145 name: MYO16_human def: "Myosin-XVI gene" [UniProtKB:Q9Y6X6] synonym: "KIAA0865" EXACT [UniProtKB:Q9Y6X6] synonym: "MYO16B" EXACT [UniProtKB:Q9Y6X6] xref: EMBL:AB020672 xref: EMBL:AK095691 xref: EMBL:AK127806 xref: EMBL:AL136132 xref: EMBL:AL157771 xref: EMBL:AL161431 xref: EMBL:AL353143 xref: EMBL:AL390918 xref: EMBL:AL834447 xref: HGNC:HGNC:29822 xref: UniGene:Hs.656587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002267 ! MYO16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005146 name: MYO6_human def: "Myosin-VI gene" [UniProtKB:Q9UM54] synonym: "KIAA0389" EXACT [UniProtKB:Q9UM54] xref: EMBL:AB002387 xref: EMBL:AF229082 xref: EMBL:AF229083 xref: EMBL:AF229084 xref: EMBL:AF229085 xref: EMBL:AF229086 xref: EMBL:AF229087 xref: EMBL:AF229088 xref: EMBL:AF229089 xref: EMBL:AF229090 xref: EMBL:AF229091 xref: EMBL:AF229092 xref: EMBL:AF229093 xref: EMBL:AF229094 xref: EMBL:AF229095 xref: EMBL:AF229096 xref: EMBL:AF229097 xref: EMBL:AF229098 xref: EMBL:AF229099 xref: EMBL:AF229100 xref: EMBL:AF229101 xref: EMBL:AF229102 xref: EMBL:AF229103 xref: EMBL:AF229104 xref: EMBL:AF229105 xref: EMBL:AF229106 xref: EMBL:AF229107 xref: EMBL:AF229108 xref: EMBL:AF229109 xref: EMBL:AF229110 xref: EMBL:AF229111 xref: EMBL:AL109897 xref: EMBL:AL136093 xref: EMBL:U90236 xref: HGNC:HGNC:7605 xref: UniGene:Hs.149387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006261 ! MYO6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005147 name: MYOD1_human def: "Myoblast determination protein 1 gene" [UniProtKB:P15172] synonym: "MYF3" EXACT [UniProtKB:P15172] synonym: "MYOD" EXACT [UniProtKB:P15172] xref: EMBL:AF027148 xref: EMBL:BC064493 xref: EMBL:BT007157 xref: EMBL:CH471064 xref: EMBL:X17650 xref: EMBL:X56677 xref: HGNC:HGNC:7611 xref: UniGene:Hs.181768 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005705 ! MYOD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005148 name: MYOZ1_human def: "Myozenin-1 gene" [UniProtKB:Q9NP98] synonym: "MYOZ" EXACT [UniProtKB:Q9NP98] xref: EMBL:AF240633 xref: EMBL:AF243387 xref: EMBL:AF243388 xref: EMBL:AF243389 xref: EMBL:AF243390 xref: EMBL:AJ278124 xref: EMBL:AL359210 xref: EMBL:AY013297 xref: EMBL:BC025753 xref: HGNC:HGNC:13752 xref: UniGene:Hs.238756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005306 ! MYOZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005149 name: MYOZ2_human def: "Myozenin-2 gene" [UniProtKB:Q9NPC6] synonym: "C4orf5" EXACT [UniProtKB:Q9NPC6] xref: EMBL:AF007160 xref: EMBL:AF249873 xref: EMBL:AF267992 xref: EMBL:AF267994 xref: EMBL:AF267997 xref: EMBL:AJ252149 xref: EMBL:AY013295 xref: EMBL:BC005195 xref: EMBL:BC017402 xref: EMBL:BC020932 xref: EMBL:BT007214 xref: HGNC:HGNC:1330 xref: UniGene:Hs.381047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005250 ! MYOZ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005150 name: MPZ_human def: "Myelin P0 protein precursor gene" [UniProtKB:P25189] xref: EMBL:AK313555 xref: EMBL:AL592295 xref: EMBL:BC006491 xref: EMBL:BT006765 xref: EMBL:CH471121 xref: EMBL:D10537 xref: EMBL:D14720 xref: EMBL:L24893 xref: EMBL:L24894 xref: EMBL:S66705 xref: EMBL:U10017 xref: EMBL:U10018 xref: HGNC:HGNC:7225 xref: UniGene:Hs.591486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006337 ! MYP0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005151 name: MYST2_human def: "Histone acetyltransferase MYST2 gene" [UniProtKB:O95251] synonym: "HBO1" EXACT [UniProtKB:O95251] synonym: "HBOa" EXACT [UniProtKB:O95251] xref: EMBL:AF074606 xref: EMBL:AF140360 xref: EMBL:AF217502 xref: EMBL:BC032640 xref: HGNC:HGNC:17016 xref: UniGene:Hs.21907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005399 ! MYST2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005152 name: MYT1L_human def: "Myelin transcription factor 1-like protein gene" [UniProtKB:Q9UL68] synonym: "KIAA1106" EXACT [UniProtKB:Q9UL68] xref: EMBL:AB029029 xref: EMBL:AF036943 xref: EMBL:BC043230 xref: EMBL:BC071612 xref: EMBL:BC150281 xref: HGNC:HGNC:7623 xref: UniGene:Hs.434418 xref: UniGene:Hs.669852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005601 ! MYT1L_HUMAN relationship: codes_for CCO:B0053945 ! A7E2C7_HUMAN relationship: codes_for CCO:B0056301 ! Q49A74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005153 name: MYT1_human def: "Myelin transcription factor 1 gene" [UniProtKB:Q01538] synonym: "KIAA0835" EXACT [UniProtKB:Q01538] synonym: "KIAA1050" EXACT [UniProtKB:Q01538] synonym: "MTF1" EXACT [UniProtKB:Q01538] synonym: "MYTI" EXACT [UniProtKB:Q01538] synonym: "PLPB1" EXACT [UniProtKB:Q01538] xref: EMBL:AB020642 xref: EMBL:AB028973 xref: EMBL:AL121581 xref: EMBL:BC062313 xref: EMBL:M96980 xref: HGNC:HGNC:7622 xref: UniGene:Hs.279562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005607 ! MYT1_HUMAN relationship: codes_for CCO:B0056894 ! Q6P6D5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005154 name: NACA_human def: "Nascent polypeptide-associated complex subunit alpha gene" [UniProtKB:Q13765] synonym: "HSD48" EXACT [UniProtKB:Q13765] xref: EMBL:AF054187 xref: EMBL:AK223085 xref: EMBL:AY034001 xref: EMBL:AY605660 xref: EMBL:AY911673 xref: EMBL:BC105120 xref: EMBL:BC105122 xref: EMBL:BC106041 xref: EMBL:CR450295 xref: EMBL:X80909 xref: HGNC:HGNC:7629 xref: UniGene:Hs.505735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006096 ! NACA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005155 name: QPRT_human def: "Nicotinate-nucleotide pyrophosphorylase [carboxylating] gene" [UniProtKB:Q15274] xref: EMBL:BC005060 xref: EMBL:BC010033 xref: EMBL:BC018910 xref: EMBL:BT007231 xref: EMBL:D78177 xref: HGNC:HGNC:9755 xref: UniGene:Hs.513484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005174 ! NADC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005156 name: NASP_human def: "Nuclear autoantigenic sperm protein gene" [UniProtKB:P49321] xref: EMBL:AK222816 xref: EMBL:AL355480 xref: EMBL:BC003113 xref: EMBL:BC010105 xref: EMBL:BC011580 xref: EMBL:BC053608 xref: EMBL:M97856 xref: HGNC:HGNC:7644 xref: UniGene:Hs.319334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001626 ! NASP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005157 name: NAT6_human def: "N-acetyltransferase 6 gene" [UniProtKB:Q93015] synonym: "FUS2" EXACT [UniProtKB:Q93015] xref: EMBL:AF040705 xref: EMBL:AF040706 xref: EMBL:BC004483 xref: EMBL:U73167 xref: HGNC:HGNC:30252 xref: UniGene:Hs.129910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002026 ! NAT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005158 name: NBL1_human def: "Neuroblastoma suppressor of tumorigenicity 1 precursor gene" [UniProtKB:P41271] synonym: "DAN" EXACT [UniProtKB:P41271] synonym: "DAND1" EXACT [UniProtKB:P41271] xref: EMBL:AY049783 xref: EMBL:BC012037 xref: EMBL:D28124 xref: EMBL:D89013 xref: HGNC:HGNC:7650 xref: UniGene:Hs.466662 xref: UniGene:Hs.654502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001607 ! NBL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005159 name: NBN_human def: "Nibrin gene" [UniProtKB:O60934] synonym: "NBS" EXACT [UniProtKB:O60934] synonym: "NBS1" EXACT [UniProtKB:O60934] synonym: "P95" EXACT [UniProtKB:O60934] xref: EMBL:AB013139 xref: EMBL:AF051334 xref: EMBL:AF058696 xref: EMBL:AF069291 xref: EMBL:AK223256 xref: EMBL:AY566246 xref: EMBL:BC108650 xref: EMBL:BX640816 xref: HGNC:HGNC:7652 xref: UniGene:Hs.492208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001421 ! NBN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005160 name: NCOA6_human def: "Nuclear receptor coactivator 6 gene" [UniProtKB:Q14686] synonym: "AIB3" EXACT [UniProtKB:Q14686] synonym: "KIAA0181" EXACT [UniProtKB:Q14686] synonym: "RAP250" EXACT [UniProtKB:Q14686] synonym: "TRBP" EXACT [UniProtKB:Q14686] xref: EMBL:AF128458 xref: EMBL:AF171667 xref: EMBL:AF177388 xref: EMBL:AF208227 xref: EMBL:AF245115 xref: EMBL:AL109824 xref: EMBL:CH471077 xref: EMBL:D80003 xref: HGNC:HGNC:15936 xref: UniGene:Hs.368971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005893 ! NCOA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005161 name: NCOA7_human def: "Nuclear receptor coactivator 7 gene" [UniProtKB:Q8NI08] synonym: "ERAP140" EXACT [UniProtKB:Q8NI08] synonym: "ESNA1" EXACT [UniProtKB:Q8NI08] synonym: "Nbla00052" EXACT [UniProtKB:Q8NI08] synonym: "Nbla10993" EXACT [UniProtKB:Q8NI08] xref: EMBL:AB074157 xref: EMBL:AF493978 xref: EMBL:AK094706 xref: EMBL:AL035689 xref: EMBL:AL078594 xref: EMBL:AL136163 xref: EMBL:AL832628 xref: EMBL:BC036461 xref: EMBL:BC071782 xref: EMBL:BX537385 xref: HGNC:HGNC:21081 xref: UniGene:Hs.171426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005552 ! NCOA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005162 name: NCOR2_human def: "Nuclear receptor corepressor 2 gene" [UniProtKB:Q9Y618] synonym: "CTG26" EXACT [UniProtKB:Q9Y618] xref: EMBL:AF113003 xref: EMBL:AF125672 xref: EMBL:S83390 xref: EMBL:U37146 xref: EMBL:U80750 xref: EMBL:U80761 xref: HGNC:HGNC:7673 xref: UniGene:Hs.137510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005553 ! NCOR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005163 name: NDE1_human def: "Nuclear distribution protein nudE homolog 1 gene" [UniProtKB:Q9NXR1] synonym: "NUDE" EXACT [UniProtKB:Q9NXR1] xref: EMBL:AC026401 xref: EMBL:AF001548 xref: EMBL:AK000108 xref: EMBL:BC001421 xref: EMBL:BC033900 xref: HGNC:HGNC:17619 xref: UniGene:Hs.655378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002173 ! NDE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005164 name: NDEL1_human def: "Nuclear distribution protein nudE-like 1 gene" [UniProtKB:Q9GZM8] synonym: "EOPA" EXACT [UniProtKB:Q9GZM8] synonym: "MITAP1" EXACT [UniProtKB:Q9GZM8] synonym: "NUDEL" EXACT [UniProtKB:Q9GZM8] xref: EMBL:AF182078 xref: EMBL:AF217798 xref: EMBL:AL832648 xref: EMBL:AY004871 xref: EMBL:BC026101 xref: HGNC:HGNC:17620 xref: UniGene:Hs.372123 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005926 ! NDEL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005165 name: NME3_human def: "Nucleoside diphosphate kinase 3 gene" [UniProtKB:Q13232] xref: EMBL:AE006639 xref: EMBL:BC000250 xref: EMBL:U29656 xref: HGNC:HGNC:7851 xref: UniGene:Hs.514065 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005316 ! NDK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005166 name: NME7_human def: "Nucleoside diphosphate kinase 7 gene" [UniProtKB:Q9Y5B8] xref: EMBL:AF153191 xref: EMBL:AL031726 xref: EMBL:AL356852 xref: EMBL:BC006983 xref: EMBL:Z99758 xref: HGNC:HGNC:20461 xref: UniGene:Hs.702359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005294 ! NDK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005167 name: NME1_human def: "Nucleoside diphosphate kinase A gene" [UniProtKB:P15531] synonym: "NDPKA" EXACT [UniProtKB:P15531] synonym: "NM23" EXACT [UniProtKB:P15531] xref: EMBL:BC000293 xref: EMBL:BC018994 xref: EMBL:X17620 xref: EMBL:X73066 xref: EMBL:X75598 xref: HGNC:HGNC:7849 xref: UniGene:Hs.463456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001524 ! NDKA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005168 name: NME2_human def: "Nucleoside diphosphate kinase B gene" [UniProtKB:P22392] synonym: "NM23B" EXACT [UniProtKB:P22392] xref: EMBL:BC002476 xref: EMBL:L16785 xref: EMBL:M36981 xref: EMBL:X58965 xref: HGNC:HGNC:7850 xref: UniGene:Hs.463456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001546 ! NDKB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005169 name: NME4_human def: "Nucleoside diphosphate kinase, mitochondrial precursor gene" [UniProtKB:O00746] synonym: "NM23D" EXACT [UniProtKB:O00746] xref: EMBL:AE006463 xref: EMBL:BC004880 xref: EMBL:BC017067 xref: EMBL:Y07604 xref: EMBL:Z97634 xref: HGNC:HGNC:7852 xref: UniGene:Hs.9235 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005206 ! NDKM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005170 name: NDUFB8_human def: "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial precursor gene" [UniProtKB:O95169] xref: EMBL:AF044958 xref: EMBL:AF077028 xref: EMBL:AF115968 xref: EMBL:AL080056 xref: EMBL:AL133352 xref: EMBL:BC000466 xref: EMBL:BC019276 xref: EMBL:CR533490 xref: EMBL:Y18944 xref: HGNC:HGNC:7703 xref: UniGene:Hs.523215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006289 ! NDUB8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005171 name: PPP1R9B_human def: "Neurabin-2 gene" [UniProtKB:Q96SB3] synonym: "PPP1R6" EXACT [UniProtKB:Q96SB3] xref: EMBL:AJ401189 xref: EMBL:AL713642 xref: HGNC:HGNC:9298 xref: UniGene:Hs.514323 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002060 ! NEB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005172 name: NDN_human def: "Necdin gene" [UniProtKB:Q99608] xref: EMBL:AB007828 xref: EMBL:BC008750 xref: EMBL:U35139 xref: HGNC:HGNC:7675 xref: UniGene:Hs.50130 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002075 ! NECD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005173 name: NEDD8_human def: "NEDD8 precursor gene" [UniProtKB:Q15843] xref: EMBL:BC104200 xref: EMBL:BC104201 xref: EMBL:BC104664 xref: EMBL:CR407662 xref: EMBL:D23662 xref: HGNC:HGNC:7732 xref: UniGene:Hs.531064 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005331 ! NEDD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005174 name: NEK11_human def: "Serine/threonine-protein kinase Nek11 gene" [UniProtKB:Q8NG66] xref: EMBL:AB071996 xref: EMBL:AB071997 xref: EMBL:AK027148 xref: EMBL:AL833472 xref: EMBL:BC028587 xref: HGNC:HGNC:18593 xref: UniGene:Hs.657336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001984 ! NEK11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005175 name: NEK1_human def: "Serine/threonine-protein kinase Nek1 gene" [UniProtKB:Q96PY6] synonym: "KIAA1901" EXACT [UniProtKB:Q96PY6] xref: EMBL:AB067488 xref: EMBL:AC084724 xref: EMBL:AC116615 xref: EMBL:AC116621 xref: EMBL:AF155113 xref: EMBL:AK025658 xref: EMBL:AK027580 xref: EMBL:BC015147 xref: EMBL:BC037790 xref: EMBL:BC114491 xref: EMBL:CR933642 xref: HGNC:HGNC:7744 xref: UniGene:Hs.481181 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002055 ! NEK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005176 name: NEK2_human def: "Serine/threonine-protein kinase Nek2 gene" [UniProtKB:P51955] synonym: "NLK1" EXACT [UniProtKB:P51955] xref: EMBL:AC096637 xref: EMBL:AK223353 xref: EMBL:AL356310 xref: EMBL:AY045701 xref: EMBL:BC043502 xref: EMBL:BC052807 xref: EMBL:BC065932 xref: EMBL:BT019729 xref: EMBL:U11050 xref: EMBL:Z25425 xref: EMBL:Z29066 xref: HGNC:HGNC:7745 xref: UniGene:Hs.153704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001654 ! NEK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005177 name: NEK4_human def: "Serine/threonine-protein kinase Nek4 gene" [UniProtKB:P51957] synonym: "STK2" EXACT [UniProtKB:P51957] xref: EMBL:L20321 xref: HGNC:HGNC:11399 xref: UniGene:Hs.631921 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001655 ! NEK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005178 name: NEK6_human def: "Serine/threonine-protein kinase Nek6 gene" [UniProtKB:Q9HC98] xref: EMBL:AB026289 xref: EMBL:AF087909 xref: EMBL:AK313071 xref: EMBL:AL137846 xref: EMBL:AL162724 xref: EMBL:BC000101 xref: EMBL:BC004174 xref: EMBL:BC004209 xref: EMBL:BC012761 xref: EMBL:CH471090 xref: EMBL:CR457091 xref: EMBL:CR542222 xref: HGNC:HGNC:7749 xref: UniGene:Hs.197071 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002145 ! NEK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005179 name: NEK9_human def: "Serine/threonine-protein kinase Nek9 gene" [UniProtKB:Q8TD19] synonym: "KIAA1995" EXACT [UniProtKB:Q8TD19] synonym: "NEK8" EXACT [UniProtKB:Q8TD19] synonym: "NERCC" EXACT [UniProtKB:Q8TD19] xref: EMBL:AB082526 xref: EMBL:AC007055 xref: EMBL:AY048580 xref: EMBL:AY080896 xref: EMBL:BC009336 xref: EMBL:BC093881 xref: EMBL:BC112101 xref: HGNC:HGNC:18591 xref: UniGene:Hs.696132 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001991 ! NEK9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005180 name: NELF_human def: "Nasal embryonic luteinizing hormone-releasing hormone factor gene" [UniProtKB:Q6X4W1] xref: EMBL:AK027474 xref: EMBL:AK074602 xref: EMBL:AL365502 xref: EMBL:AL389944 xref: EMBL:AL389945 xref: EMBL:AL389946 xref: EMBL:AY255128 xref: EMBL:AY255129 xref: EMBL:AY255130 xref: EMBL:AY255131 xref: EMBL:AY255132 xref: EMBL:BC072412 xref: HGNC:HGNC:29843 xref: UniGene:Hs.455336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005972 ! NELF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005181 name: NELL1_human def: "Protein kinase C-binding protein NELL1 precursor gene" [UniProtKB:Q92832] synonym: "NRP1" EXACT [UniProtKB:Q92832] xref: EMBL:BC096101 xref: EMBL:D83017 xref: EMBL:U57523 xref: HGNC:HGNC:7750 xref: UniGene:Hs.657172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005973 ! NELL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005182 name: NELL2_human def: "Protein kinase C-binding protein NELL2 precursor gene" [UniProtKB:Q99435] synonym: "NRP2" EXACT [UniProtKB:Q99435] xref: EMBL:BC020544 xref: EMBL:D83018 xref: HGNC:HGNC:7751 xref: UniGene:Hs.505326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005427 ! NELL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005183 name: IKBKG_human def: "NF-kappa-B essential modulator gene" [UniProtKB:Q9Y6K9] synonym: "FIP3" EXACT [UniProtKB:Q9Y6K9] synonym: "NEMO" EXACT [UniProtKB:Q9Y6K9] xref: EMBL:AF062089 xref: EMBL:AF074382 xref: EMBL:AF091453 xref: EMBL:AF261086 xref: EMBL:AJ271718 xref: EMBL:AY114157 xref: EMBL:BC000299 xref: EMBL:BC012114 xref: EMBL:BC050612 xref: EMBL:BT019621 xref: HGNC:HGNC:5961 xref: UniGene:Hs.43505 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005524 ! NEMO_HUMAN relationship: codes_for CCO:B0030841 ! Q7Z7F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005184 name: EMG1_human def: "Probable ribosome biogenesis protein NEP1 gene" [UniProtKB:Q92979] synonym: "C2F" EXACT [UniProtKB:Q92979] xref: EMBL:BC055314 xref: EMBL:U47924 xref: EMBL:U72514 xref: HGNC:HGNC:16912 xref: UniGene:Hs.558447 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006260 ! NEP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005185 name: MME_human def: "Neprilysin gene" [UniProtKB:P08473] synonym: "EPN" EXACT [UniProtKB:P08473] xref: EMBL:BC101632 xref: EMBL:BC101658 xref: EMBL:J03779 xref: EMBL:M26607 xref: EMBL:M26608 xref: EMBL:M26609 xref: EMBL:M26610 xref: EMBL:M26611 xref: EMBL:M26612 xref: EMBL:M26613 xref: EMBL:M26614 xref: EMBL:M26615 xref: EMBL:M26616 xref: EMBL:M26617 xref: EMBL:M26618 xref: EMBL:M26619 xref: EMBL:M26620 xref: EMBL:M26621 xref: EMBL:M26622 xref: EMBL:M26623 xref: EMBL:M26624 xref: EMBL:M26625 xref: EMBL:M26626 xref: EMBL:M26627 xref: EMBL:M26628 xref: EMBL:X07166 xref: EMBL:Y00811 xref: HGNC:HGNC:7154 xref: UniGene:Hs.307734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005760 ! NEP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005186 name: NF1_human def: "Neurofibromin gene" [UniProtKB:P21359] xref: EMBL:AY796305 xref: EMBL:D10490 xref: EMBL:D12625 xref: EMBL:M38106 xref: EMBL:M38107 xref: EMBL:M38108 xref: EMBL:M38109 xref: EMBL:M38110 xref: EMBL:M38111 xref: EMBL:M38112 xref: EMBL:M38113 xref: EMBL:M38114 xref: EMBL:M38115 xref: EMBL:M38116 xref: EMBL:M60496 xref: EMBL:M60915 xref: EMBL:M61213 xref: EMBL:M82814 xref: EMBL:M89914 xref: EMBL:S51751 xref: EMBL:U17656 xref: EMBL:U17659 xref: EMBL:U17662 xref: EMBL:U17667 xref: EMBL:U17668 xref: EMBL:U17673 xref: EMBL:U17676 xref: EMBL:U17677 xref: EMBL:U17680 xref: EMBL:U17681 xref: EMBL:U17682 xref: EMBL:U17683 xref: EMBL:U17684 xref: EMBL:U17685 xref: EMBL:U17686 xref: EMBL:U17687 xref: EMBL:U17688 xref: EMBL:U17689 xref: EMBL:U17690 xref: EMBL:Y07853 xref: HGNC:HGNC:7765 xref: UniGene:Hs.113577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001542 ! NF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005187 name: NFKB2_human def: "Nuclear factor NF-kappa-B p100 subunit gene" [UniProtKB:Q00653] synonym: "LYT10" EXACT [UniProtKB:Q00653] xref: EMBL:AK292654 xref: EMBL:AL121928 xref: EMBL:AY865619 xref: EMBL:BC002844 xref: EMBL:BT009769 xref: EMBL:CH471066 xref: EMBL:S76638 xref: EMBL:U09609 xref: EMBL:U20816 xref: EMBL:X61498 xref: EMBL:X61499 xref: HGNC:HGNC:7795 xref: UniGene:Hs.73090 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005527 ! NFKB2_HUMAN relationship: codes_for CCO:B0053982 ! A8K9D9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005188 name: NEFL_human def: "Neurofilament light polypeptide gene" [UniProtKB:P07196] synonym: "NF68" EXACT [UniProtKB:P07196] synonym: "NFL" EXACT [UniProtKB:P07196] xref: EMBL:AY156690 xref: EMBL:BC039237 xref: EMBL:S70309 xref: EMBL:X05608 xref: HGNC:HGNC:7739 xref: UniGene:Hs.521461 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006343 ! NFL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005189 name: NFYA_human def: "Nuclear transcription factor Y subunit alpha gene" [UniProtKB:P23511] xref: EMBL:AL031778 xref: EMBL:BC039244 xref: EMBL:M59079 xref: EMBL:X59711 xref: HGNC:HGNC:7804 xref: UniGene:Hs.10441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005384 ! NFYA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005190 name: NFYB_human def: "Nuclear transcription factor Y subunit beta gene" [UniProtKB:P25208] synonym: "HAP3" EXACT [UniProtKB:P25208] xref: EMBL:BC005316 xref: EMBL:BC005317 xref: EMBL:BC007035 xref: EMBL:L06145 xref: EMBL:X59710 xref: HGNC:HGNC:7805 xref: UniGene:Hs.84928 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005382 ! NFYB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005191 name: NFYC_human def: "Nuclear transcription factor Y subunit gamma gene" [UniProtKB:Q13952] xref: EMBL:AC119677 xref: EMBL:AF191744 xref: EMBL:AK000346 xref: EMBL:AL354914 xref: EMBL:BC005003 xref: EMBL:BT020081 xref: EMBL:D85425 xref: EMBL:D89986 xref: EMBL:U62296 xref: EMBL:U78774 xref: EMBL:Z74792 xref: HGNC:HGNC:7806 xref: UniGene:Hs.233458 xref: UniGene:Hs.703333 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001770 ! NFYC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005192 name: NEUROG1_human def: "Neurogenin-1 gene" [UniProtKB:Q92886] synonym: "NEUROD3" EXACT [UniProtKB:Q92886] synonym: "NGN" EXACT [UniProtKB:Q92886] synonym: "NGN1" EXACT [UniProtKB:Q92886] xref: EMBL:BC008687 xref: EMBL:BC028226 xref: EMBL:U63842 xref: HGNC:HGNC:7764 xref: UniGene:Hs.248149 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002022 ! NGN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005193 name: NHP2L1_human def: "NHP2-like protein 1 gene" [UniProtKB:P55769] xref: EMBL:AF091076 xref: EMBL:AF155235 xref: EMBL:BC005358 xref: EMBL:BC019282 xref: EMBL:CR456531 xref: EMBL:D50420 xref: EMBL:Z83840 xref: HGNC:HGNC:7819 xref: UniGene:Hs.182255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001676 ! NH2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005194 name: NIF3L1_human def: "NIF3-like protein 1 gene" [UniProtKB:Q9GZT8] synonym: "ALS2CR1" EXACT [UniProtKB:Q9GZT8] synonym: "MDS015" EXACT [UniProtKB:Q9GZT8] synonym: "My018" EXACT [UniProtKB:Q9GZT8] xref: EMBL:AB038949 xref: EMBL:AC005037 xref: EMBL:AF060513 xref: EMBL:AF182416 xref: EMBL:AF283538 xref: EMBL:AK023378 xref: EMBL:BC007654 xref: EMBL:CH471063 xref: HGNC:HGNC:13390 xref: UniGene:Hs.145284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005260 ! NIF3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005195 name: ZC3HC1_human def: "Nuclear-interacting partner of ALK gene" [UniProtKB:Q86WB0] synonym: "HSPC216" EXACT [UniProtKB:Q86WB0] synonym: "NIPA" EXACT [UniProtKB:Q86WB0] xref: EMBL:AC073320 xref: EMBL:AC087071 xref: EMBL:AF151050 xref: EMBL:AJ537494 xref: EMBL:AK001317 xref: EMBL:AK022373 xref: EMBL:BC011551 xref: EMBL:BC028917 xref: HGNC:HGNC:29913 xref: UniGene:Hs.194157 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001941 ! NIPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005196 name: NIPBL_human def: "Nipped-B-like protein gene" [UniProtKB:Q6KC79] synonym: "IDN3" EXACT [UniProtKB:Q6KC79] xref: EMBL:AB019494 xref: EMBL:AB019602 xref: EMBL:AJ627032 xref: EMBL:AJ640137 xref: EMBL:AK126804 xref: EMBL:BC033847 xref: EMBL:BX538177 xref: EMBL:BX538178 xref: EMBL:BX640644 xref: HGNC:HGNC:28862 xref: UniGene:Hs.481927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001908 ! NIPBL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005197 name: NIPSNAP1_human def: "Protein NipSnap homolog 1 gene" [UniProtKB:Q9BPW8] xref: EMBL:AJ001258 xref: EMBL:BC002371 xref: EMBL:BC006473 xref: HGNC:HGNC:7827 xref: UniGene:Hs.173878 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006298 ! NIPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005198 name: NKRF_human def: "NF-kappa-B-repressing factor gene" [UniProtKB:O15226] synonym: "ITBA4" EXACT [UniProtKB:O15226] synonym: "NRF" EXACT [UniProtKB:O15226] xref: EMBL:AJ011812 xref: EMBL:AY208891 xref: EMBL:BC040379 xref: EMBL:BC047878 xref: EMBL:Y07707 xref: HGNC:HGNC:19374 xref: UniGene:Hs.437084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006038 ! NKRF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005199 name: NMI_human def: "N-myc-interactor gene" [UniProtKB:Q13287] xref: EMBL:AC009311 xref: EMBL:BC001268 xref: EMBL:U32849 xref: HGNC:HGNC:7854 xref: UniGene:Hs.54483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005695 ! NMI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005200 name: SC65_human def: "Synaptonemal complex protein SC65 gene" [UniProtKB:Q92791] synonym: "NOL55" EXACT [UniProtKB:Q92791] xref: EMBL:AJ250583 xref: EMBL:AK222945 xref: EMBL:BC001047 xref: EMBL:BC007942 xref: EMBL:BC011701 xref: EMBL:U47621 xref: UniGene:Hs.446459 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002018 ! SC65_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005201 name: NOC4L_human def: "Nucleolar complex protein 4 homolog gene" [UniProtKB:Q9BVI4] xref: EMBL:AK074489 xref: EMBL:BC001191 xref: EMBL:BC007893 xref: EMBL:BC071958 xref: HGNC:HGNC:28461 xref: UniGene:Hs.558536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005282 ! NOC4L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005202 name: GTPBP4_human def: "Nucleolar GTP-binding protein 1 gene" [UniProtKB:Q9BZE4] synonym: "CRFG" EXACT [UniProtKB:Q9BZE4] synonym: "NOG1" EXACT [UniProtKB:Q9BZE4] xref: EMBL:AF120334 xref: EMBL:AF325353 xref: EMBL:AK001552 xref: EMBL:BC038975 xref: HGNC:HGNC:21535 xref: UniGene:Hs.215766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002116 ! NOG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005203 name: NOG_human def: "Noggin precursor gene" [UniProtKB:Q13253] xref: EMBL:BC034027 xref: EMBL:U31202 xref: HGNC:HGNC:7866 xref: UniGene:Hs.248201 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005328 ! NOGG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005204 name: NOL12_human def: "Nucleolar protein 12 gene" [UniProtKB:Q9UGY1] xref: EMBL:AL160132 xref: EMBL:BC002808 xref: EMBL:CR456463 xref: EMBL:Z83844 xref: HGNC:HGNC:28585 xref: UniGene:Hs.632778 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006336 ! NOL12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005205 name: NOL1_human def: "Putative RNA methyltransferase NOL1 gene" [UniProtKB:P46087] xref: EMBL:BC000656 xref: EMBL:BC065257 xref: EMBL:BC128183 xref: EMBL:BC128184 xref: EMBL:M32110 xref: EMBL:M33132 xref: EMBL:X55504 xref: HGNC:HGNC:7867 xref: UniGene:Hs.534334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001623 ! NOL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005206 name: NOLC1_human def: "Nucleolar phosphoprotein p130 gene" [UniProtKB:Q14978] synonym: "KIAA0035" EXACT [UniProtKB:Q14978] xref: EMBL:AL500527 xref: EMBL:AY820769 xref: EMBL:BC001883 xref: EMBL:CH471066 xref: EMBL:D21262 xref: EMBL:Z34289 xref: HGNC:HGNC:15608 xref: UniGene:Hs.523238 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001793 ! NOLC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005207 name: NONO_human def: "Non-POU domain-containing octamer-binding protein gene" [UniProtKB:Q15233] synonym: "NRB54" EXACT [UniProtKB:Q15233] xref: EMBL:BC002364 xref: EMBL:BC003129 xref: EMBL:BC012141 xref: EMBL:BC028299 xref: EMBL:BC069616 xref: EMBL:BC069639 xref: EMBL:CR456761 xref: EMBL:L14599 xref: EMBL:U02493 xref: EMBL:U89867 xref: EMBL:Y11289 xref: EMBL:Y11290 xref: EMBL:Y11291 xref: EMBL:Y11292 xref: EMBL:Y11293 xref: EMBL:Y11294 xref: EMBL:Y11295 xref: EMBL:Y11296 xref: EMBL:Y11297 xref: EMBL:Y11298 xref: HGNC:HGNC:7871 xref: UniGene:Hs.533282 xref: UniGene:Hs.700344 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005234 ! NONO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005208 name: NOTCH1_human def: "Neurogenic locus notch homolog protein 1 precursor gene" [UniProtKB:P46531] synonym: "TAN1" EXACT [UniProtKB:P46531] xref: EMBL:AB209873 xref: EMBL:AF308602 xref: EMBL:AL354671 xref: EMBL:AL592301 xref: EMBL:M73980 xref: HGNC:HGNC:7881 xref: UniGene:Hs.495473 xref: UniGene:Hs.698674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005974 ! NOTC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005209 name: NOTCH2_human def: "Neurogenic locus notch homolog protein 2 precursor gene" [UniProtKB:Q04721] xref: EMBL:AF308601 xref: EMBL:AF315356 xref: EMBL:AL359752 xref: EMBL:AL512503 xref: EMBL:AL596222 xref: EMBL:U77493 xref: HGNC:HGNC:7882 xref: UniGene:Hs.487360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001719 ! NOTC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005210 name: NAP1L1_human def: "Nucleosome assembly protein 1-like 1 gene" [UniProtKB:P55209] synonym: "NRP" EXACT [UniProtKB:P55209] xref: EMBL:AL162068 xref: EMBL:BC002387 xref: EMBL:BT007023 xref: EMBL:M86667 xref: HGNC:HGNC:7637 xref: UniGene:Hs.524599 xref: UniGene:Hs.695185 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005376 ! NP1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005211 name: NPM2_human def: "Nucleoplasmin-2 gene" [UniProtKB:Q86SE8] xref: EMBL:AY262113 xref: EMBL:AY262114 xref: HGNC:HGNC:7930 xref: UniGene:Hs.131055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001936 ! NPM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005212 name: NPM1_human def: "Nucleophosmin gene" [UniProtKB:P06748] synonym: "NPM" EXACT [UniProtKB:P06748] xref: EMBL:AB042278 xref: EMBL:AY347529 xref: EMBL:AY740634 xref: EMBL:AY740635 xref: EMBL:AY740636 xref: EMBL:AY740637 xref: EMBL:AY740638 xref: EMBL:AY740639 xref: EMBL:AY740640 xref: EMBL:BC002398 xref: EMBL:BC008495 xref: EMBL:BC009623 xref: EMBL:BC012566 xref: EMBL:BC014349 xref: EMBL:BC016716 xref: EMBL:BC016768 xref: EMBL:BC016824 xref: EMBL:BC021668 xref: EMBL:BC021983 xref: EMBL:BC050628 xref: EMBL:BC107754 xref: EMBL:BT007011 xref: EMBL:D45915 xref: EMBL:DQ303464 xref: EMBL:J02590 xref: EMBL:M23613 xref: EMBL:M26697 xref: EMBL:M28699 xref: EMBL:M31004 xref: EMBL:U04946 xref: EMBL:U41742 xref: EMBL:U41743 xref: EMBL:U89309 xref: EMBL:U89310 xref: EMBL:U89311 xref: EMBL:U89313 xref: EMBL:U89314 xref: EMBL:U89317 xref: EMBL:U89319 xref: EMBL:U89321 xref: EMBL:X16934 xref: HGNC:HGNC:7910 xref: UniGene:Hs.557550 xref: UniGene:Hs.654469 xref: UniGene:Hs.654583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001495 ! NPM_HUMAN relationship: codes_for CCO:B0002114 ! Q9BYG9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005213 name: ITGB1BP3_human def: "Nicotinamide riboside kinase 2 gene" [UniProtKB:Q9NPI5] synonym: "NRK2" EXACT [UniProtKB:Q9NPI5] xref: EMBL:AF190819 xref: EMBL:AK001663 xref: EMBL:AK022514 xref: EMBL:AL365377 xref: EMBL:AY611481 xref: EMBL:BC093637 xref: EMBL:BC101575 xref: HGNC:HGNC:17871 xref: UniGene:Hs.135458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006315 ! NRK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005214 name: NRP1_human def: "Neuropilin-1 precursor gene" [UniProtKB:O14786] synonym: "NRP" EXACT [UniProtKB:O14786] synonym: "VEGF165R" EXACT [UniProtKB:O14786] xref: EMBL:AF016050 xref: EMBL:AF018956 xref: EMBL:AF145712 xref: EMBL:AL121748 xref: EMBL:AL353600 xref: EMBL:BC007533 xref: EMBL:BT006995 xref: HGNC:HGNC:8004 xref: UniGene:Hs.131704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005447 ! NRP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005215 name: NRXN1_human def: "Neurexin-1-alpha precursor gene" [UniProtKB:Q9ULB1] synonym: "KIAA0578" EXACT [UniProtKB:Q9ULB1] xref: EMBL:AB011150 xref: EMBL:AB035356 xref: EMBL:AC007462 xref: EMBL:AC007682 xref: EMBL:AC009234 xref: EMBL:AC068715 xref: EMBL:AC068725 xref: EMBL:AC069550 xref: EMBL:AC078994 xref: HGNC:HGNC:8008 xref: UniGene:Hs.637685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005545 ! NRX1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005216 name: NSL1_human def: "Kinetochore-associated protein NSL1 homolog gene" [UniProtKB:Q96IY1] synonym: "C1orf48" EXACT [UniProtKB:Q96IY1] synonym: "DC31" EXACT [UniProtKB:Q96IY1] synonym: "DC8" EXACT [UniProtKB:Q96IY1] xref: EMBL:AC104333 xref: EMBL:AF201941 xref: EMBL:AF255793 xref: EMBL:AL050084 xref: EMBL:AL591647 xref: EMBL:BC007067 xref: HGNC:HGNC:24548 xref: UniGene:Hs.497692 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002043 ! NSL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005217 name: SMPD3_human def: "Sphingomyelin phosphodiesterase 3 gene" [UniProtKB:Q9NY59] xref: EMBL:AJ250460 xref: EMBL:BC112238 xref: HGNC:HGNC:14240 xref: UniGene:Hs.368421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002175 ! NSMA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005218 name: NUTF2_human def: "Nuclear transport factor 2 gene" [UniProtKB:P61970] synonym: "NTF2" EXACT [UniProtKB:P61970] xref: EMBL:BC002348 xref: EMBL:CR456937 xref: EMBL:U43939 xref: EMBL:X07315 xref: HGNC:HGNC:13722 xref: UniGene:Hs.696342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006067 ! NTF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005219 name: NUAK2_human def: "NUAK family SNF1-like kinase 2 gene" [UniProtKB:Q9H093] synonym: "SNARK" EXACT [UniProtKB:Q9H093] xref: EMBL:AK074830 xref: EMBL:AL136891 xref: EMBL:BC017306 xref: HGNC:HGNC:29558 xref: UniGene:Hs.497512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005874 ! NUAK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005220 name: NCL_human def: "Nucleolin gene" [UniProtKB:P19338] xref: EMBL:AC017104 xref: EMBL:AK091742 xref: EMBL:M60858 xref: HGNC:HGNC:7667 xref: UniGene:Hs.79110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005733 ! NUCL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005221 name: NUDT10_human def: "Diphosphoinositol polyphosphate phosphohydrolase 3-alpha gene" [UniProtKB:Q8NFP7] synonym: "APS2" EXACT [UniProtKB:Q8NFP7] synonym: "DIPP3A" EXACT [UniProtKB:Q8NFP7] xref: EMBL:AF469196 xref: EMBL:AL158055 xref: EMBL:BC049383 xref: EMBL:BC050700 xref: HGNC:HGNC:17621 xref: UniGene:Hs.375178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006344 ! NUD10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005222 name: NUDCD3_human def: "NudC domain-containing protein 3 gene" [UniProtKB:Q8IVD9] synonym: "KIAA1068" EXACT [UniProtKB:Q8IVD9] xref: EMBL:AB028991 xref: EMBL:AC004453 xref: EMBL:AK024226 xref: EMBL:BC003691 xref: EMBL:BC011673 xref: EMBL:BC035014 xref: HGNC:HGNC:22208 xref: UniGene:Hs.488171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005198 ! NUDC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005223 name: NUDC_human def: "Nuclear migration protein nudC gene" [UniProtKB:Q9Y266] xref: EMBL:AB019408 xref: EMBL:AF086922 xref: EMBL:AF100760 xref: EMBL:AF125465 xref: EMBL:AF130736 xref: EMBL:AL136725 xref: EMBL:AL356390 xref: EMBL:BC002399 xref: EMBL:BC003132 xref: EMBL:BC006147 xref: EMBL:BC007280 xref: EMBL:BC015153 xref: EMBL:BC021139 xref: HGNC:HGNC:8045 xref: UniGene:Hs.263812 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002250 ! NUDC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005224 name: NUF2_human def: "Kinetochore protein Nuf2 gene" [UniProtKB:Q9BZD4] synonym: "CDCA1" EXACT [UniProtKB:Q9BZD4] synonym: "NUF2R" EXACT [UniProtKB:Q9BZD4] xref: EMBL:AB050577 xref: EMBL:AB050578 xref: EMBL:AF326731 xref: EMBL:AK093348 xref: EMBL:AL592435 xref: EMBL:BC008489 xref: EMBL:BC021171 xref: HGNC:HGNC:14621 xref: UniGene:Hs.651950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002115 ! NUF2_HUMAN relationship: codes_for CCO:B0041237 ! B1AQT3_HUMAN relationship: codes_for CCO:B0041238 ! B1AQT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005225 name: NUMA1_human def: "Nuclear mitotic apparatus protein 1 gene" [UniProtKB:Q14980] synonym: "NUMA" EXACT [UniProtKB:Q14980] xref: EMBL:Z11583 xref: EMBL:Z11584 xref: HGNC:HGNC:8059 xref: UniGene:Hs.325978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001794 ! NUMA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005226 name: NUSAP1_human def: "Nucleolar and spindle-associated protein 1 gene" [UniProtKB:Q9BXS6] synonym: "ANKT" EXACT [UniProtKB:Q9BXS6] synonym: "BM-037" EXACT [UniProtKB:Q9BXS6] synonym: "PRO0310" EXACT [UniProtKB:Q9BXS6] xref: EMBL:AF090915 xref: EMBL:AF217513 xref: EMBL:AF290612 xref: EMBL:AF305711 xref: EMBL:AK023483 xref: EMBL:AK222819 xref: EMBL:BC001308 xref: EMBL:BC010838 xref: EMBL:BC012887 xref: EMBL:BC024772 xref: EMBL:CH471125 xref: HGNC:HGNC:18538 xref: UniGene:Hs.615092 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002108 ! NUSAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005228 name: OBSCN_human def: "Obscurin gene" [UniProtKB:Q5VST9] synonym: "KIAA1556" EXACT [UniProtKB:Q5VST9] synonym: "KIAA1639" EXACT [UniProtKB:Q5VST9] xref: EMBL:AB046776 xref: EMBL:AB046859 xref: EMBL:AJ002535 xref: EMBL:AJ314896 xref: EMBL:AJ314898 xref: EMBL:AJ314900 xref: EMBL:AJ314901 xref: EMBL:AJ314903 xref: EMBL:AJ314904 xref: EMBL:AJ314905 xref: EMBL:AJ314906 xref: EMBL:AJ314907 xref: EMBL:AJ314908 xref: EMBL:AK097489 xref: EMBL:AL353593 xref: EMBL:AL359510 xref: EMBL:AL670729 xref: EMBL:AM231061 xref: EMBL:BC043916 xref: HGNC:HGNC:15719 xref: UniGene:Hs.650039 xref: UniGene:Hs.656999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005645 ! OBSCN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005229 name: DLST_human def: "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor gene" [UniProtKB:P36957] synonym: "DLTS" EXACT [UniProtKB:P36957] xref: EMBL:AC006530 xref: EMBL:AK289414 xref: EMBL:BC000302 xref: EMBL:BC001922 xref: EMBL:CH471061 xref: EMBL:D16373 xref: EMBL:D26535 xref: EMBL:L37418 xref: HGNC:HGNC:2911 xref: UniGene:Hs.525459 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006185 ! ODO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005230 name: OGT_human def: "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit gene" [UniProtKB:O15294] xref: EMBL:AJ315767 xref: EMBL:AL050366 xref: EMBL:AL833085 xref: EMBL:BC014434 xref: EMBL:BC038180 xref: EMBL:BX537844 xref: EMBL:U77413 xref: HGNC:HGNC:8127 xref: UniGene:Hs.405410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005806 ! OGT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005231 name: OLA1_human def: "Obg-like ATPase 1 gene" [UniProtKB:Q9NTK5] synonym: "GTPBP9" EXACT [UniProtKB:Q9NTK5] synonym: "PRO2455" EXACT [UniProtKB:Q9NTK5] synonym: "PTD004" EXACT [UniProtKB:Q9NTK5] xref: EMBL:AF078859 xref: EMBL:AF078868 xref: EMBL:AF116703 xref: EMBL:AF134478 xref: EMBL:AK027523 xref: EMBL:AK074710 xref: EMBL:AL136546 xref: EMBL:BC012842 xref: EMBL:BC013925 xref: EMBL:BC029376 xref: EMBL:BC091522 xref: HGNC:HGNC:28833 xref: UniGene:Hs.157351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006040 ! OLA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005232 name: ORC1L_human def: "Origin recognition complex subunit 1 gene" [UniProtKB:Q13415] synonym: "ORC1" EXACT [UniProtKB:Q13415] synonym: "PARC1" EXACT [UniProtKB:Q13415] xref: EMBL:AL513218 xref: EMBL:U40152 xref: EMBL:U43416 xref: HGNC:HGNC:8487 xref: UniGene:Hs.17908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005352 ! ORC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005233 name: ORC2L_human def: "Origin recognition complex subunit 2 gene" [UniProtKB:Q13416] synonym: "ORC2" EXACT [UniProtKB:Q13416] xref: EMBL:AY652588 xref: EMBL:BC014834 xref: EMBL:U27459 xref: EMBL:U40268 xref: HGNC:HGNC:8488 xref: UniGene:Hs.444870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005353 ! ORC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005234 name: ORC3L_human def: "Origin recognition complex subunit 3 gene" [UniProtKB:Q9UBD5] synonym: "LATHEO" EXACT [UniProtKB:Q9UBD5] xref: EMBL:AF093535 xref: EMBL:AF125507 xref: EMBL:AF135044 xref: EMBL:AK222795 xref: EMBL:AL080116 xref: EMBL:AL133211 xref: EMBL:AL451126 xref: EMBL:AY623113 xref: EMBL:BC035494 xref: EMBL:BC047689 xref: EMBL:U50950 xref: HGNC:HGNC:8489 xref: UniGene:Hs.410228 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005392 ! ORC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005235 name: ORC4L_human def: "Origin recognition complex subunit 4 gene" [UniProtKB:O43929] xref: EMBL:AF022108 xref: EMBL:AF047598 xref: EMBL:AF132596 xref: EMBL:AY600302 xref: EMBL:BC014847 xref: HGNC:HGNC:8490 xref: UniGene:Hs.558364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005389 ! ORC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005236 name: ORC5L_human def: "Origin recognition complex subunit 5 gene" [UniProtKB:O43913] xref: EMBL:AF047599 xref: EMBL:AF049127 xref: EMBL:AF081459 xref: EMBL:BC023652 xref: EMBL:U92538 xref: HGNC:HGNC:8491 xref: UniGene:Hs.432948 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005390 ! ORC5_HUMAN relationship: codes_for CCO:B0054744 ! O95268_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005237 name: ORC6L_human def: "Origin recognition complex subunit 6 gene" [UniProtKB:Q9Y5N6] xref: EMBL:AF139658 xref: EMBL:BC039032 xref: EMBL:BC063565 xref: HGNC:HGNC:17151 xref: UniGene:Hs.49760 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005388 ! ORC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005238 name: OSBPL1A_human def: "Oxysterol-binding protein-related protein 1 gene" [UniProtKB:Q9BXW6] synonym: "ORP1" EXACT [UniProtKB:Q9BXW6] synonym: "OSBP8" EXACT [UniProtKB:Q9BXW6] synonym: "OSBPL1" EXACT [UniProtKB:Q9BXW6] synonym: "OSBPL1B" EXACT [UniProtKB:Q9BXW6] xref: EMBL:AF274714 xref: EMBL:AF323726 xref: EMBL:AF392449 xref: EMBL:AF392450 xref: EMBL:AK001079 xref: HGNC:HGNC:16398 xref: UniGene:Hs.370725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006009 ! OSBL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005239 name: OSGIN2_human def: "Oxidative stress-induced growth inhibitor 2 gene" [UniProtKB:Q9Y236] synonym: "C8orf1" EXACT [UniProtKB:Q9Y236] xref: EMBL:AF061326 xref: EMBL:AF069291 xref: EMBL:BC031054 xref: HGNC:HGNC:1355 xref: UniGene:Hs.436445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002246 ! OSGI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005240 name: OVOL1_human def: "Putative transcription factor Ovo-like 1 gene" [UniProtKB:O14753] xref: EMBL:AF016045 xref: EMBL:BC059408 xref: EMBL:BX648725 xref: HGNC:HGNC:8525 xref: UniGene:Hs.134434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001358 ! OVOL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005241 name: PPP2R3B_human def: "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta gene" [UniProtKB:Q9Y5P8] synonym: "PPP2R3L" EXACT [UniProtKB:Q9Y5P8] xref: EMBL:AF135016 xref: EMBL:BC063429 xref: EMBL:BK000521 xref: HGNC:HGNC:13417 xref: UniGene:Hs.124942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002258 ! P2R3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005243 name: PIK3C2A_human def: "Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide gene" [UniProtKB:O00443] xref: EMBL:BC113658 xref: EMBL:Y13367 xref: HGNC:HGNC:8971 xref: UniGene:Hs.175343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006071 ! P3C2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005244 name: PIK3C2B_human def: "Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide gene" [UniProtKB:O00750] xref: EMBL:AL606489 xref: EMBL:Y11312 xref: EMBL:Y13892 xref: HGNC:HGNC:8972 xref: UniGene:Hs.497487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005711 ! P3C2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005245 name: TP53_human def: "Cellular tumor antigen p53 gene" [UniProtKB:P04637] synonym: "P53" EXACT [UniProtKB:P04637] xref: EMBL:AB082923 xref: EMBL:AF135120 xref: EMBL:AF135121 xref: EMBL:AF136270 xref: EMBL:AF136271 xref: EMBL:AF209128 xref: EMBL:AF209129 xref: EMBL:AF209130 xref: EMBL:AF209131 xref: EMBL:AF209132 xref: EMBL:AF209133 xref: EMBL:AF209134 xref: EMBL:AF209135 xref: EMBL:AF209136 xref: EMBL:AF209148 xref: EMBL:AF209149 xref: EMBL:AF209150 xref: EMBL:AF209151 xref: EMBL:AF209152 xref: EMBL:AF209153 xref: EMBL:AF209154 xref: EMBL:AF209155 xref: EMBL:AF209156 xref: EMBL:AF210308 xref: EMBL:AF210309 xref: EMBL:AF210310 xref: EMBL:AF240684 xref: EMBL:AF240685 xref: EMBL:AF307851 xref: EMBL:AM076971 xref: EMBL:AY270155 xref: EMBL:AY359814 xref: EMBL:AY390341 xref: EMBL:AY429684 xref: EMBL:AY838896 xref: EMBL:BC003596 xref: EMBL:DQ186648 xref: EMBL:DQ186649 xref: EMBL:DQ186650 xref: EMBL:DQ186652 xref: EMBL:EF101869 xref: EMBL:K03199 xref: EMBL:M13112 xref: EMBL:M13113 xref: EMBL:M13114 xref: EMBL:M13115 xref: EMBL:M13116 xref: EMBL:M13117 xref: EMBL:M13118 xref: EMBL:M13119 xref: EMBL:M13120 xref: EMBL:M13121 xref: EMBL:M14694 xref: EMBL:M14695 xref: EMBL:M22882 xref: EMBL:M22883 xref: EMBL:M22884 xref: EMBL:M22887 xref: EMBL:M22888 xref: EMBL:M22894 xref: EMBL:M22895 xref: EMBL:M22896 xref: EMBL:M22897 xref: EMBL:M22898 xref: EMBL:U63714 xref: EMBL:U94788 xref: EMBL:X01405 xref: EMBL:X02469 xref: EMBL:X54156 xref: EMBL:X60011 xref: EMBL:X60012 xref: EMBL:X60013 xref: EMBL:X60014 xref: EMBL:X60015 xref: EMBL:X60016 xref: EMBL:X60017 xref: EMBL:X60018 xref: EMBL:X60019 xref: EMBL:X60020 xref: HGNC:HGNC:11998 xref: UniGene:Hs.654481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001483 ! P53_HUMAN relationship: codes_for CCO:B0001831 ! Q3LRW5_HUMAN relationship: codes_for CCO:B0022296 ! Q3LRW1_HUMAN relationship: codes_for CCO:B0022298 ! Q3LRW4_HUMAN relationship: codes_for CCO:B0022308 ! Q1MSW9_HUMAN relationship: codes_for CCO:B0022312 ! Q3LRW3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005246 name: GATAD2A_human def: "Transcriptional repressor p66-alpha gene" [UniProtKB:Q86YP4] xref: EMBL:AK000092 xref: EMBL:AL390164 xref: EMBL:AY186731 xref: EMBL:BC011684 xref: EMBL:BC012902 xref: HGNC:HGNC:29989 xref: UniGene:Hs.696033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005907 ! P66A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005247 name: GATAD2B_human def: "Transcriptional repressor p66-beta gene" [UniProtKB:Q8WXI9] synonym: "KIAA1150" EXACT [UniProtKB:Q8WXI9] xref: EMBL:AB032976 xref: EMBL:AF411836 xref: EMBL:AL513523 xref: EMBL:BC069419 xref: EMBL:BC112052 xref: EMBL:BC112080 xref: HGNC:HGNC:30778 xref: UniGene:Hs.4779 xref: UniGene:Hs.596854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005908 ! P66B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005248 name: TP73_human def: "Tumor protein p73 gene" [UniProtKB:O15350] synonym: "P73" EXACT [UniProtKB:O15350] xref: EMBL:AB055065 xref: EMBL:AB055066 xref: EMBL:AF077616 xref: EMBL:AF077617 xref: EMBL:AF077618 xref: EMBL:AF077619 xref: EMBL:AF077620 xref: EMBL:AF077621 xref: EMBL:AF077624 xref: EMBL:AF077625 xref: EMBL:AF077626 xref: EMBL:AF077627 xref: EMBL:AF077628 xref: EMBL:AF079082 xref: EMBL:AF079083 xref: EMBL:AF079084 xref: EMBL:AF079085 xref: EMBL:AF079086 xref: EMBL:AF079087 xref: EMBL:AF079088 xref: EMBL:AF079089 xref: EMBL:AF079090 xref: EMBL:AF079091 xref: EMBL:AF079092 xref: EMBL:AF079093 xref: EMBL:AF079094 xref: EMBL:AL136528 xref: EMBL:AY040827 xref: EMBL:AY040828 xref: EMBL:AY040829 xref: EMBL:BC117251 xref: EMBL:BC117253 xref: EMBL:Y11416 xref: HGNC:HGNC:12003 xref: UniGene:Hs.697294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001374 ! P73_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005249 name: COIL_human def: "Coilin gene" [UniProtKB:P38432] synonym: "CLN80" EXACT [UniProtKB:P38432] xref: EMBL:BC010385 xref: EMBL:M58411 xref: EMBL:U06632 xref: HGNC:HGNC:2184 xref: UniGene:Hs.532795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005621 ! P80C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005250 name: PAFAH1B2_human def: "Platelet-activating factor acetylhydrolase IB subunit beta gene" [UniProtKB:P68402] synonym: "PAFAHB" EXACT [UniProtKB:P68402] xref: EMBL:BC000398 xref: EMBL:BC019301 xref: EMBL:D63390 xref: HGNC:HGNC:8575 xref: UniGene:Hs.696131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006291 ! PA1B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005251 name: PAFAH1B3_human def: "Platelet-activating factor acetylhydrolase IB subunit gamma gene" [UniProtKB:Q15102] synonym: "PAFAHG" EXACT [UniProtKB:Q15102] xref: EMBL:AC006486 xref: EMBL:BC003016 xref: EMBL:BC007863 xref: EMBL:D63391 xref: HGNC:HGNC:8576 xref: UniGene:Hs.466831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006098 ! PA1B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005252 name: PA2G4_human def: "Proliferation-associated protein 2G4 gene" [UniProtKB:Q9UQ80] synonym: "EBP1" EXACT [UniProtKB:Q9UQ80] xref: EMBL:AF104668 xref: EMBL:AF104669 xref: EMBL:AF104670 xref: EMBL:BC001951 xref: EMBL:BC007561 xref: EMBL:BC069786 xref: EMBL:U59435 xref: EMBL:U87954 xref: HGNC:HGNC:8550 xref: UniGene:Hs.524498 xref: UniGene:Hs.573018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002239 ! PA2G4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005253 name: PABPC1_human def: "Polyadenylate-binding protein 1 gene" [UniProtKB:P11940] synonym: "PAB1" EXACT [UniProtKB:P11940] synonym: "PABP1" EXACT [UniProtKB:P11940] synonym: "PABPC2" EXACT [UniProtKB:P11940] xref: EMBL:BC015958 xref: EMBL:BC023520 xref: EMBL:BC041863 xref: EMBL:U68093 xref: EMBL:U68094 xref: EMBL:U68095 xref: EMBL:U68097 xref: EMBL:U68098 xref: EMBL:U68099 xref: EMBL:U68100 xref: EMBL:U68101 xref: EMBL:U68102 xref: EMBL:U68103 xref: EMBL:U68104 xref: EMBL:Y00345 xref: EMBL:Z48501 xref: HGNC:HGNC:8554 xref: UniGene:Hs.387804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005854 ! PABP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005254 name: ADCYAP1_human def: "Pituitary adenylate cyclase-activating polypeptide precursor gene" [UniProtKB:P18509] xref: EMBL:BC093837 xref: EMBL:BC101803 xref: EMBL:S83513 xref: EMBL:X60435 xref: HGNC:HGNC:241 xref: UniGene:Hs.531719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001532 ! PACA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005255 name: PAEP_human def: "Glycodelin precursor gene" [UniProtKB:P09466] xref: EMBL:AL050169 xref: EMBL:AL354761 xref: EMBL:BC069451 xref: EMBL:BC069562 xref: EMBL:BC112304 xref: EMBL:BC113728 xref: EMBL:J04129 xref: EMBL:M34046 xref: EMBL:M61886 xref: HGNC:HGNC:8573 xref: UniGene:Hs.532325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006212 ! PAEP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005256 name: PAK1_human def: "Serine/threonine-protein kinase PAK 1 gene" [UniProtKB:Q13153] xref: EMBL:AF071884 xref: EMBL:BC109299 xref: EMBL:U24152 xref: EMBL:U51120 xref: HGNC:HGNC:8590 xref: UniGene:Hs.435714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005469 ! PAK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005257 name: PANX3_human def: "Pannexin-3 gene" [UniProtKB:Q96QZ0] xref: EMBL:AF406650 xref: HGNC:HGNC:20573 xref: UniGene:Hs.99235 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006029 ! PANX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005258 name: PAPD5_human def: "PAP-associated domain-containing protein 5 gene" [UniProtKB:Q8NDF8] xref: EMBL:AF089897 xref: EMBL:AK001141 xref: EMBL:AK097589 xref: EMBL:AL833922 xref: HGNC:HGNC:30758 xref: UniGene:Hs.514342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001975 ! PAPD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005259 name: PARP12_human def: "Poly [ADP-ribose] polymerase 12 gene" [UniProtKB:Q9H0J9] synonym: "ZC3HDC1" EXACT [UniProtKB:Q9H0J9] xref: EMBL:AC004849 xref: EMBL:AC004961 xref: EMBL:AC025816 xref: EMBL:AK026346 xref: EMBL:AL136766 xref: EMBL:AL137255 xref: EMBL:BC081541 xref: HGNC:HGNC:21919 xref: UniGene:Hs.12646 xref: UniGene:Hs.308710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006037 ! PAR12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005260 name: F2R_human def: "Proteinase-activated receptor 1 precursor gene" [UniProtKB:P25116] synonym: "CF2R" EXACT [UniProtKB:P25116] synonym: "PAR1" EXACT [UniProtKB:P25116] synonym: "TR" EXACT [UniProtKB:P25116] xref: EMBL:AF391809 xref: EMBL:BC002464 xref: EMBL:BC051909 xref: EMBL:M62424 xref: HGNC:HGNC:3537 xref: UniGene:Hs.482562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001557 ! PAR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005261 name: PARD3B_human def: "Partitioning defective 3 homolog B gene" [UniProtKB:Q8TEW8] synonym: "ALS2CR19" EXACT [UniProtKB:Q8TEW8] synonym: "PAR3B" EXACT [UniProtKB:Q8TEW8] synonym: "PAR3L" EXACT [UniProtKB:Q8TEW8] xref: EMBL:AB053321 xref: EMBL:AB073472 xref: EMBL:AB092439 xref: EMBL:AF428250 xref: EMBL:AF428251 xref: EMBL:AF466152 xref: EMBL:AK056157 xref: EMBL:AK057965 xref: HGNC:HGNC:14446 xref: UniGene:Hs.657382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001997 ! PAR3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005262 name: PARD6A_human def: "Partitioning defective 6 homolog alpha gene" [UniProtKB:Q9NPB6] synonym: "PAR6A" EXACT [UniProtKB:Q9NPB6] xref: EMBL:AB041642 xref: EMBL:AB043634 xref: EMBL:AF028827 xref: EMBL:AF252292 xref: EMBL:AF265565 xref: EMBL:AJ277095 xref: EMBL:BC015626 xref: HGNC:HGNC:15943 xref: UniGene:Hs.112933 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002150 ! PAR6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005263 name: PARD6B_human def: "Partitioning defective 6 homolog beta gene" [UniProtKB:Q9BYG5] synonym: "PAR6B" EXACT [UniProtKB:Q9BYG5] xref: EMBL:AB044555 xref: EMBL:AL031680 xref: EMBL:BC060847 xref: HGNC:HGNC:16245 xref: UniGene:Hs.589848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002113 ! PAR6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005264 name: PARD6G_human def: "Partitioning defective 6 homolog gamma gene" [UniProtKB:Q9BYG4] synonym: "PAR6G" EXACT [UniProtKB:Q9BYG4] xref: EMBL:AB044556 xref: EMBL:BC060797 xref: HGNC:HGNC:16076 xref: UniGene:Hs.654920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002112 ! PAR6G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005265 name: PARC_human def: "p53-associated parkin-like cytoplasmic protein gene" [UniProtKB:Q8IWT3] synonym: "H7AP1" EXACT [UniProtKB:Q8IWT3] synonym: "KIAA0708" EXACT [UniProtKB:Q8IWT3] xref: EMBL:AB014608 xref: EMBL:AJ318215 xref: EMBL:AK125228 xref: EMBL:AK129649 xref: EMBL:AY145132 xref: EMBL:BC002879 xref: EMBL:CR749511 xref: EMBL:CR749841 xref: UniGene:Hs.485434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001949 ! PARC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005266 name: PARD3_human def: "Partitioning defective 3 homolog gene" [UniProtKB:Q8TEW0] synonym: "PAR3" EXACT [UniProtKB:Q8TEW0] synonym: "PAR3A" EXACT [UniProtKB:Q8TEW0] xref: EMBL:AB073671 xref: EMBL:AF177228 xref: EMBL:AF196185 xref: EMBL:AF196186 xref: EMBL:AF252293 xref: EMBL:AF332592 xref: EMBL:AF332593 xref: EMBL:AF467002 xref: EMBL:AF467003 xref: EMBL:AF467004 xref: EMBL:AF467005 xref: EMBL:AF467006 xref: EMBL:AK000761 xref: EMBL:AK027735 xref: EMBL:BC011711 xref: HGNC:HGNC:16051 xref: UniGene:Hs.131489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001996 ! PARD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005267 name: PARK7_human def: "Protein DJ-1 gene" [UniProtKB:Q99497] xref: EMBL:AB045294 xref: EMBL:AB073864 xref: EMBL:AF021819 xref: EMBL:AL034417 xref: EMBL:AY648999 xref: EMBL:BC008188 xref: EMBL:D61380 xref: HGNC:HGNC:16369 xref: UniGene:Hs.419640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005443 ! PARK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005268 name: PARN_human def: "Poly(A)-specific ribonuclease PARN gene" [UniProtKB:O95453] synonym: "DAN" EXACT [UniProtKB:O95453] xref: EMBL:AJ005698 xref: EMBL:BC050029 xref: HGNC:HGNC:8609 xref: UniGene:Hs.253197 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005347 ! PARN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005269 name: PARP1_human def: "Poly [ADP-ribose] polymerase 1 gene" [UniProtKB:P09874] synonym: "ADPRT" EXACT [UniProtKB:P09874] synonym: "PPOL" EXACT [UniProtKB:P09874] xref: EMBL:AF524947 xref: EMBL:BC037545 xref: EMBL:J03473 xref: EMBL:M17081 xref: EMBL:M18112 xref: EMBL:M29544 xref: EMBL:M29545 xref: EMBL:M29766 xref: EMBL:M29767 xref: EMBL:M29768 xref: EMBL:M29769 xref: EMBL:M29770 xref: EMBL:M29771 xref: EMBL:M29772 xref: EMBL:M29773 xref: EMBL:M29774 xref: EMBL:M29775 xref: EMBL:M29776 xref: EMBL:M29777 xref: EMBL:M29778 xref: EMBL:M29779 xref: EMBL:M29780 xref: EMBL:M29781 xref: EMBL:M29782 xref: EMBL:M29783 xref: EMBL:M29784 xref: EMBL:M29785 xref: EMBL:M29786 xref: EMBL:M32721 xref: EMBL:M60436 xref: EMBL:X16674 xref: EMBL:X56140 xref: EMBL:X56141 xref: HGNC:HGNC:270 xref: UniGene:Hs.177766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005467 ! PARP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005270 name: PAX5_human def: "Paired box protein Pax-5 gene" [UniProtKB:Q02548] xref: EMBL:AF080573 xref: EMBL:AY463953 xref: EMBL:AY463954 xref: EMBL:AY463955 xref: EMBL:AY463956 xref: EMBL:AY463957 xref: EMBL:CH471071 xref: EMBL:DQ841178 xref: EMBL:DQ845345 xref: EMBL:DQ845346 xref: EMBL:M96944 xref: HGNC:HGNC:8619 xref: UniGene:Hs.654464 xref: UniGene:Hs.684503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005340 ! PAX5_HUMAN relationship: codes_for CCO:B0031646 ! Q6S731_HUMAN relationship: codes_for CCO:B0031650 ! Q6S729_HUMAN relationship: codes_for CCO:B0031655 ! Q6S732_HUMAN relationship: codes_for CCO:B0031656 ! Q6S728_HUMAN relationship: codes_for CCO:B0031660 ! Q6S730_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005271 name: PXN_human def: "Paxillin gene" [UniProtKB:P49023] xref: EMBL:AC004263 xref: EMBL:D86862 xref: EMBL:D86863 xref: EMBL:U14588 xref: EMBL:U87941 xref: EMBL:U87942 xref: EMBL:U87943 xref: EMBL:U87944 xref: EMBL:U87945 xref: EMBL:U87946 xref: HGNC:HGNC:9718 xref: UniGene:Hs.446336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005837 ! PAXI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005272 name: PBRM1_human def: "Protein polybromo-1 gene" [UniProtKB:Q86U86] synonym: "PB1" EXACT [UniProtKB:Q86U86] xref: EMBL:AF177387 xref: EMBL:AF197569 xref: EMBL:AF225870 xref: EMBL:AF225871 xref: EMBL:AF225872 xref: EMBL:AK056541 xref: EMBL:AY281068 xref: EMBL:BC115009 xref: EMBL:BC115010 xref: EMBL:BC115011 xref: EMBL:BC129934 xref: EMBL:BC129935 xref: HGNC:HGNC:30064 xref: UniGene:Hs.189920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001938 ! PB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005273 name: PBX2_human def: "Pre-B-cell leukemia transcription factor 2 gene" [UniProtKB:P40425] synonym: "G17" EXACT [UniProtKB:P40425] xref: EMBL:AL662830 xref: EMBL:AL662884 xref: EMBL:AL845464 xref: EMBL:BC082261 xref: EMBL:D28769 xref: EMBL:U89336 xref: EMBL:X59842 xref: EMBL:X80700 xref: HGNC:HGNC:8633 xref: UniGene:Hs.509545 xref: UniGene:Hs.534342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005895 ! PBX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005274 name: PCAF_human def: "Histone acetyltransferase PCAF gene" [UniProtKB:Q92831] xref: EMBL:BC060823 xref: EMBL:BC070075 xref: EMBL:U57317 xref: HGNC:HGNC:8638 xref: UniGene:Hs.533055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002019 ! PCAF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005275 name: PCDHA4_human def: "Protocadherin alpha-4 precursor gene" [UniProtKB:Q9UN74] xref: EMBL:AC005609 xref: EMBL:AF152312 xref: EMBL:AF152482 xref: HGNC:HGNC:8670 xref: UniGene:Hs.199343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006099 ! PCDA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005276 name: PCDH9_human def: "Protocadherin-9 precursor gene" [UniProtKB:Q9HC56] xref: EMBL:AF169692 xref: EMBL:AL136999 xref: EMBL:AL138814 xref: EMBL:AL355173 xref: EMBL:AL603863 xref: EMBL:AL834258 xref: EMBL:BC136626 xref: EMBL:BC136627 xref: EMBL:BX537422 xref: HGNC:HGNC:8661 xref: UniGene:Hs.654709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006022 ! PCDH9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005277 name: PCGF6_human def: "Polycomb group RING finger protein 6 gene" [UniProtKB:Q9BYE7] synonym: "MBLR" EXACT [UniProtKB:Q9BYE7] synonym: "RNF134" EXACT [UniProtKB:Q9BYE7] xref: EMBL:AB047006 xref: EMBL:AK027885 xref: EMBL:AL591408 xref: EMBL:BC007602 xref: EMBL:BC010235 xref: HGNC:HGNC:21156 xref: UniGene:Hs.335808 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002111 ! PCGF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005278 name: PCNA_human def: "Proliferating cell nuclear antigen gene" [UniProtKB:P12004] xref: EMBL:AF527838 xref: EMBL:AL121924 xref: EMBL:BC000491 xref: EMBL:BC062439 xref: EMBL:J04718 xref: EMBL:M15796 xref: HGNC:HGNC:8729 xref: UniGene:Hs.147433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001513 ! PCNA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005279 name: PCNP_human def: "PEST proteolytic signal-containing nuclear protein gene" [UniProtKB:Q8WW12] xref: EMBL:AB037675 xref: EMBL:BC013916 xref: EMBL:BC022001 xref: EMBL:CR627371 xref: HGNC:HGNC:30023 xref: UniGene:Hs.654949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002005 ! PCNP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005280 name: PCNT_human def: "Pericentrin gene" [UniProtKB:O95613] synonym: "KIAA0402" EXACT [UniProtKB:O95613] synonym: "PCNT2" EXACT [UniProtKB:O95613] xref: EMBL:AB007862 xref: EMBL:AF515282 xref: EMBL:AK093923 xref: EMBL:U52962 xref: HGNC:HGNC:16068 xref: UniGene:Hs.474069 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006078 ! PCNT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005283 name: PCTK3_human def: "Serine/threonine-protein kinase PCTAIRE-3 gene" [UniProtKB:Q07002] xref: EMBL:AL357131 xref: EMBL:AY353237 xref: EMBL:AY353238 xref: EMBL:BC011526 xref: EMBL:BT007299 xref: EMBL:CH471067 xref: EMBL:X66362 xref: HGNC:HGNC:8751 xref: UniGene:Hs.445402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005295 ! PCTK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005284 name: PDCD4_human def: "Programmed cell death protein 4 gene" [UniProtKB:Q53EL6] synonym: "H731" EXACT [UniProtKB:Q53EL6] xref: EMBL:AK223623 xref: EMBL:AL136368 xref: EMBL:AL158163 xref: EMBL:BC015036 xref: EMBL:BC026104 xref: EMBL:BC031049 xref: EMBL:U83908 xref: EMBL:U96628 xref: HGNC:HGNC:8763 xref: UniGene:Hs.232543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001836 ! PDCD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005285 name: PDCD5_human def: "Programmed cell death protein 5 gene" [UniProtKB:O14737] synonym: "TFAR19" EXACT [UniProtKB:O14737] xref: EMBL:AF014955 xref: EMBL:BC015519 xref: EMBL:BT006694 xref: EMBL:CR456934 xref: HGNC:HGNC:8764 xref: UniGene:Hs.443831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006152 ! PDCD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005286 name: PDE6D_human def: "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta gene" [UniProtKB:O43924] synonym: "PDED" EXACT [UniProtKB:O43924] xref: EMBL:AF022912 xref: EMBL:AF042833 xref: EMBL:AF042834 xref: EMBL:AF042835 xref: EMBL:AF045999 xref: EMBL:AJ001626 xref: EMBL:BC007831 xref: EMBL:BT007278 xref: HGNC:HGNC:8788 xref: UniGene:Hs.516808 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006130 ! PDE6D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005287 name: PDGFA_human def: "Platelet-derived growth factor subunit A precursor gene" [UniProtKB:P04085] synonym: "PDGF1" EXACT [UniProtKB:P04085] xref: EMBL:A09204 xref: EMBL:BC109246 xref: EMBL:M19984 xref: EMBL:M19985 xref: EMBL:M19986 xref: EMBL:M19987 xref: EMBL:M19988 xref: EMBL:M19989 xref: EMBL:M20488 xref: EMBL:M20489 xref: EMBL:M20490 xref: EMBL:M20491 xref: EMBL:M20492 xref: EMBL:M20493 xref: EMBL:M20494 xref: EMBL:M21571 xref: EMBL:S62078 xref: EMBL:X03795 xref: EMBL:X06374 xref: HGNC:HGNC:8799 xref: UniGene:Hs.705381 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001480 ! PDGFA_HUMAN relationship: codes_for CCO:B0001830 ! Q32M96_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005288 name: PDGFB_human def: "Platelet-derived growth factor subunit B precursor gene" [UniProtKB:P01127] synonym: "PDGF2" EXACT [UniProtKB:P01127] synonym: "SIS" EXACT [UniProtKB:P01127] xref: EMBL:BC029822 xref: EMBL:BC077725 xref: EMBL:CR456538 xref: EMBL:J00121 xref: EMBL:K01398 xref: EMBL:K01399 xref: EMBL:K01400 xref: EMBL:K01401 xref: EMBL:K01913 xref: EMBL:K01914 xref: EMBL:K01915 xref: EMBL:K01916 xref: EMBL:K01917 xref: EMBL:K01918 xref: EMBL:M12783 xref: EMBL:X00561 xref: EMBL:X02744 xref: EMBL:X02811 xref: EMBL:X03702 xref: EMBL:X98706 xref: EMBL:Z81010 xref: HGNC:HGNC:8800 xref: UniGene:Hs.1976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001469 ! PDGFB_HUMAN relationship: codes_for CCO:B0040520 ! A9UJN9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005289 name: PDGFD_human def: "Platelet-derived growth factor D precursor gene" [UniProtKB:Q9GZP0] synonym: "IEGF" EXACT [UniProtKB:Q9GZP0] synonym: "MSTP036" EXACT [UniProtKB:Q9GZP0] synonym: "SCDGFB" EXACT [UniProtKB:Q9GZP0] synonym: "UNQ1899/PRO4345" EXACT [UniProtKB:Q9GZP0] xref: EMBL:AB033832 xref: EMBL:AF113216 xref: EMBL:AF335584 xref: EMBL:AF336376 xref: EMBL:AY027517 xref: EMBL:AY027518 xref: EMBL:AY359116 xref: EMBL:BC030645 xref: HGNC:HGNC:30620 xref: UniGene:Hs.352298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002120 ! PDGFD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005290 name: P4HB_human def: "Protein disulfide-isomerase precursor gene" [UniProtKB:P07237] synonym: "ERBA2L" EXACT [UniProtKB:P07237] synonym: "PDI" EXACT [UniProtKB:P07237] synonym: "PDIA1" EXACT [UniProtKB:P07237] synonym: "PO4DB" EXACT [UniProtKB:P07237] xref: EMBL:BC010859 xref: EMBL:BC029617 xref: EMBL:BC071892 xref: EMBL:J02783 xref: EMBL:M22803 xref: EMBL:M22804 xref: EMBL:M22805 xref: EMBL:M22806 xref: EMBL:S37207 xref: EMBL:X05130 xref: EMBL:X07077 xref: HGNC:HGNC:8548 xref: UniGene:Hs.464336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006151 ! PDIA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005291 name: PDLIM1_human def: "PDZ and LIM domain protein 1 gene" [UniProtKB:O00151] synonym: "CLIM1" EXACT [UniProtKB:O00151] synonym: "CLP36" EXACT [UniProtKB:O00151] xref: EMBL:AJ310549 xref: EMBL:AL157834 xref: EMBL:AL160288 xref: EMBL:AY923052 xref: EMBL:BC000915 xref: EMBL:BC018755 xref: EMBL:U90878 xref: HGNC:HGNC:2067 xref: UniGene:Hs.368525 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005319 ! PDLI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005292 name: PDLIM5_human def: "PDZ and LIM domain protein 5 gene" [UniProtKB:Q96HC4] synonym: "ENH" EXACT [UniProtKB:Q96HC4] synonym: "L9" EXACT [UniProtKB:Q96HC4] xref: EMBL:AC093778 xref: EMBL:AC108067 xref: EMBL:AC109925 xref: EMBL:AF061258 xref: EMBL:AK291624 xref: EMBL:AY598328 xref: EMBL:BC008741 xref: EMBL:BT007328 xref: HGNC:HGNC:17468 xref: UniGene:Hs.480311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005976 ! PDLI5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005293 name: PDLIM7_human def: "PDZ and LIM domain protein 7 gene" [UniProtKB:Q9NR12] synonym: "ENIGMA" EXACT [UniProtKB:Q9NR12] xref: EMBL:AF265209 xref: EMBL:AF345904 xref: EMBL:AF345905 xref: EMBL:AF345906 xref: EMBL:BC001093 xref: EMBL:BC014521 xref: EMBL:BC067806 xref: EMBL:BC084575 xref: EMBL:L35240 xref: HGNC:HGNC:22958 xref: UniGene:Hs.533040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005224 ! PDLI7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005294 name: PDPK1_human def: "3-phosphoinositide-dependent protein kinase 1 gene" [UniProtKB:O15530] synonym: "PDK1" EXACT [UniProtKB:O15530] xref: EMBL:AF017995 xref: EMBL:BC012103 xref: EMBL:Y15056 xref: HGNC:HGNC:8816 xref: UniGene:Hs.459691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006233 ! PDPK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005295 name: PDS5A_human def: "Sister chromatid cohesion protein PDS5 homolog A gene" [UniProtKB:Q29RF7] synonym: "KIAA0648" EXACT [UniProtKB:Q29RF7] synonym: "PDS5" EXACT [UniProtKB:Q29RF7] synonym: "PIG54" EXACT [UniProtKB:Q29RF7] xref: EMBL:AB014548 xref: EMBL:AF294791 xref: EMBL:AK098331 xref: EMBL:AY550968 xref: EMBL:BC041361 xref: EMBL:BC114218 xref: EMBL:BC126225 xref: EMBL:CR749425 xref: HGNC:HGNC:29088 xref: UniGene:Hs.331431 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001829 ! PDS5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005296 name: PDZD4_human def: "PDZ domain-containing protein 4 gene" [UniProtKB:Q76G19] synonym: "KIAA1444" EXACT [UniProtKB:Q76G19] synonym: "PDZK4" EXACT [UniProtKB:Q76G19] synonym: "PDZRN4L" EXACT [UniProtKB:Q76G19] xref: EMBL:AB040877 xref: EMBL:AB103478 xref: EMBL:AK091444 xref: EMBL:BC002606 xref: EMBL:BC080584 xref: HGNC:HGNC:21167 xref: UniGene:Hs.92732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005977 ! PDZD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005297 name: PEF1_human def: "Peflin gene" [UniProtKB:Q9UBV8] synonym: "ABP32" EXACT [UniProtKB:Q9UBV8] synonym: "UNQ1845/PRO3573" EXACT [UniProtKB:Q9UBV8] xref: EMBL:AB018357 xref: EMBL:AB026628 xref: EMBL:AK001420 xref: EMBL:AY359011 xref: EMBL:BC002773 xref: EMBL:BC012561 xref: EMBL:CR542139 xref: HGNC:HGNC:30009 xref: UniGene:Hs.470417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006326 ! PEF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005298 name: PES1_human def: "Pescadillo homolog 1 gene" [UniProtKB:O00541] xref: EMBL:AC005006 xref: EMBL:BC032489 xref: EMBL:CR456539 xref: EMBL:U78310 xref: HGNC:HGNC:8848 xref: UniGene:Hs.517543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001351 ! PESC_HUMAN relationship: codes_for CCO:B0020438 ! A6NNS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005299 name: PEX19_human def: "Peroxisomal biogenesis factor 19 gene" [UniProtKB:P40855] synonym: "HK33" EXACT [UniProtKB:P40855] synonym: "OK/SW-cl.22" EXACT [UniProtKB:P40855] synonym: "PXF" EXACT [UniProtKB:P40855] xref: EMBL:AB018541 xref: EMBL:AB062286 xref: EMBL:BC000496 xref: EMBL:BT006879 xref: EMBL:X75535 xref: EMBL:Y09048 xref: HGNC:HGNC:9713 xref: UniGene:Hs.517232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005820 ! PEX19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005300 name: PEX26_human def: "Peroxisome assembly protein 26 gene" [UniProtKB:Q7Z412] xref: EMBL:AB089678 xref: EMBL:AB103106 xref: EMBL:AB103107 xref: EMBL:AB103108 xref: EMBL:AB103109 xref: EMBL:AB103110 xref: EMBL:AC016027 xref: EMBL:AK000065 xref: EMBL:AK000702 xref: EMBL:BC016280 xref: EMBL:BC047320 xref: EMBL:CR456362 xref: HGNC:HGNC:22965 xref: UniGene:Hs.517400 xref: UniGene:Hs.648441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005312 ! PEX26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005301 name: PFDN1_human def: "Prefoldin subunit 1 gene" [UniProtKB:O60925] synonym: "PFD1" EXACT [UniProtKB:O60925] xref: EMBL:AK223394 xref: EMBL:BC003620 xref: EMBL:BC006202 xref: EMBL:BC011869 xref: EMBL:Y17392 xref: HGNC:HGNC:8866 xref: UniGene:Hs.483564 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001420 ! PFD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005302 name: PGAM1_human def: "Phosphoglycerate mutase 1 gene" [UniProtKB:P18669] synonym: "CDABP0006" EXACT [UniProtKB:P18669] synonym: "PGAMA" EXACT [UniProtKB:P18669] xref: EMBL:AY007118 xref: EMBL:BC010038 xref: EMBL:BC011678 xref: EMBL:BC053356 xref: EMBL:BC066959 xref: EMBL:BC073742 xref: EMBL:J04173 xref: HGNC:HGNC:8888 xref: UniGene:Hs.592599 xref: UniGene:Hs.632918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006323 ! PGAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005303 name: HSPG2_human def: "Basement membrane-specific heparan sulfate proteoglycan core protein precursor gene" [UniProtKB:P98160] xref: EMBL:AL445795 xref: EMBL:L22078 xref: EMBL:M64283 xref: EMBL:M85289 xref: EMBL:S76436 xref: EMBL:X62515 xref: HGNC:HGNC:5273 xref: UniGene:Hs.705374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005964 ! PGBM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005304 name: HPGD_human def: "15-hydroxyprostaglandin dehydrogenase [NAD+] gene" [UniProtKB:P15428] synonym: "PGDH1" EXACT [UniProtKB:P15428] xref: EMBL:BC018986 xref: EMBL:J05594 xref: EMBL:L76465 xref: HGNC:HGNC:5154 xref: UniGene:Hs.655491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001523 ! PGDH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005305 name: PTGS2_human def: "Prostaglandin G/H synthase 2 precursor gene" [UniProtKB:P35354] synonym: "COX2" EXACT [UniProtKB:P35354] xref: EMBL:AL033533 xref: EMBL:AY229989 xref: EMBL:AY382629 xref: EMBL:AY462100 xref: EMBL:BC013734 xref: EMBL:D28235 xref: EMBL:L15326 xref: EMBL:M90100 xref: EMBL:U04636 xref: HGNC:HGNC:9605 xref: UniGene:Hs.196384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001593 ! PGH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005306 name: PHB_human def: "Prohibitin gene" [UniProtKB:P35232] xref: EMBL:BC013401 xref: EMBL:BC095460 xref: EMBL:BT007411 xref: EMBL:L14272 xref: EMBL:S85655 xref: HGNC:HGNC:8912 xref: UniGene:Hs.514303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001591 ! PHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005307 name: PHC1_human def: "Polyhomeotic-like protein 1 gene" [UniProtKB:P78364] synonym: "EDR1" EXACT [UniProtKB:P78364] synonym: "PH1" EXACT [UniProtKB:P78364] xref: EMBL:BC002871 xref: EMBL:BC017748 xref: EMBL:U89277 xref: HGNC:HGNC:3182 xref: UniGene:Hs.305985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005264 ! PHC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005308 name: PHC2_human def: "Polyhomeotic-like protein 2 gene" [UniProtKB:Q8IXK0] synonym: "EDR2" EXACT [UniProtKB:Q8IXK0] synonym: "PH2" EXACT [UniProtKB:Q8IXK0] xref: EMBL:AJ242730 xref: EMBL:AJ419231 xref: EMBL:AK128821 xref: EMBL:AL513327 xref: EMBL:BC015450 xref: EMBL:BC028396 xref: EMBL:BC029269 xref: EMBL:BC068573 xref: EMBL:BC092492 xref: EMBL:BC110863 xref: EMBL:BC130630 xref: HGNC:HGNC:3183 xref: UniGene:Hs.524271 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005978 ! PHC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005309 name: PHYHIP_human def: "Phytanoyl-CoA hydroxylase-interacting protein gene" [UniProtKB:Q92561] synonym: "DYRK1AP3" EXACT [UniProtKB:Q92561] synonym: "KIAA0273" EXACT [UniProtKB:Q92561] xref: EMBL:BC034034 xref: EMBL:BC035940 xref: EMBL:D87463 xref: HGNC:HGNC:16865 xref: UniGene:Hs.334688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006241 ! PHYIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005310 name: PIAS1_human def: "E3 SUMO-protein ligase PIAS1 gene" [UniProtKB:O75925] synonym: "DDXBP1" EXACT [UniProtKB:O75925] xref: EMBL:AF077951 xref: EMBL:AF167160 xref: EMBL:BC118587 xref: EMBL:BC121797 xref: EMBL:U78524 xref: HGNC:HGNC:2752 xref: UniGene:Hs.162458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005579 ! PIAS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005311 name: PIAS2_human def: "E3 SUMO-protein ligase PIAS2 gene" [UniProtKB:O75928] synonym: "PIASX" EXACT [UniProtKB:O75928] xref: EMBL:AC090241 xref: EMBL:AC090373 xref: EMBL:AF077953 xref: EMBL:AF077954 xref: EMBL:AF361054 xref: EMBL:BC015190 xref: HGNC:HGNC:17311 xref: UniGene:Hs.658013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005321 ! PIAS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005312 name: PIAS4_human def: "E3 SUMO-protein ligase PIAS4 gene" [UniProtKB:Q8N2W9] synonym: "PIASG" EXACT [UniProtKB:Q8N2W9] xref: EMBL:AF077952 xref: EMBL:AF164437 xref: EMBL:BC010047 xref: EMBL:BC029874 xref: EMBL:BC066895 xref: HGNC:HGNC:17002 xref: UniGene:Hs.105779 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005402 ! PIAS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005313 name: PICK1_human def: "PRKCA-binding protein gene" [UniProtKB:Q9NRD5] synonym: "PRKCABP" EXACT [UniProtKB:Q9NRD5] xref: EMBL:AB026491 xref: EMBL:AF231710 xref: EMBL:AL031587 xref: EMBL:AL049654 xref: EMBL:BC017561 xref: EMBL:CR456550 xref: HGNC:HGNC:9394 xref: UniGene:Hs.180871 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005947 ! PICK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005314 name: CDC91L1_human def: "CDC91 cell division cycle 91-like 1 (S. cerevisiae) gene" [UniProtKB:Q5JWU1] synonym: "RP11-346K17.2-004" EXACT [UniProtKB:Q5JWU1] xref: EMBL:AL118520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018187 ! Q5JWU1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005315 name: PIM2_human def: "Serine/threonine-protein kinase Pim-2 gene" [UniProtKB:Q9P1W9] xref: EMBL:AB042425 xref: EMBL:BC018111 xref: EMBL:U77735 xref: HGNC:HGNC:8987 xref: UniGene:Hs.496096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002185 ! PIM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005316 name: PIN1_human def: "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 gene" [UniProtKB:Q13526] xref: EMBL:BC002899 xref: EMBL:BT019331 xref: EMBL:CR407654 xref: EMBL:U49070 xref: HGNC:HGNC:8988 xref: UniGene:Hs.465849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001755 ! PIN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005317 name: PNN_human def: "Pinin gene" [UniProtKB:Q9H307] synonym: "DRS" EXACT [UniProtKB:Q9H307] synonym: "MEMA" EXACT [UniProtKB:Q9H307] xref: EMBL:AF112222 xref: EMBL:AF195139 xref: EMBL:AK223612 xref: EMBL:BC062602 xref: EMBL:U77718 xref: EMBL:Y09703 xref: EMBL:Y10351 xref: HGNC:HGNC:9162 xref: UniGene:Hs.409965 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002131 ! PININ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005318 name: PINX1_human def: "Pin2-interacting protein X1 gene" [UniProtKB:Q96BK5] synonym: "LPTL" EXACT [UniProtKB:Q96BK5] synonym: "LPTS" EXACT [UniProtKB:Q96BK5] xref: EMBL:AF205718 xref: EMBL:AF418553 xref: EMBL:AJ344104 xref: EMBL:AK000572 xref: EMBL:AY029161 xref: EMBL:AY238941 xref: EMBL:BC015479 xref: EMBL:BC093762 xref: UniGene:Hs.490991 xref: UniGene:Hs.583894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002033 ! PINX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005319 name: PIWIL2_human def: "Piwi-like protein 2 gene" [UniProtKB:Q8TC59] synonym: "HILI" EXACT [UniProtKB:Q8TC59] xref: EMBL:AB079367 xref: EMBL:AK001213 xref: EMBL:AK027497 xref: EMBL:BC025995 xref: EMBL:BC111751 xref: HGNC:HGNC:17644 xref: UniGene:Hs.661109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001990 ! PIWL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005320 name: PJA1_human def: "E3 ubiquitin-protein ligase Praja1 gene" [UniProtKB:Q8NG27] synonym: "RNF70" EXACT [UniProtKB:Q8NG27] xref: EMBL:AF262024 xref: EMBL:AF264620 xref: EMBL:AK021892 xref: EMBL:AL157699 xref: EMBL:BC048323 xref: EMBL:BC075803 xref: EMBL:BC105051 xref: EMBL:BC105053 xref: HGNC:HGNC:16648 xref: UniGene:Hs.522679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006202 ! PJA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005321 name: PIK3CB_human def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform gene" [UniProtKB:P42338] synonym: "PIK3C1" EXACT [UniProtKB:P42338] xref: EMBL:AJ297549 xref: EMBL:AJ297550 xref: EMBL:AJ297551 xref: EMBL:AJ297552 xref: EMBL:AJ297553 xref: EMBL:AJ297554 xref: EMBL:AJ297555 xref: EMBL:AJ297556 xref: EMBL:AJ297557 xref: EMBL:AJ297558 xref: EMBL:AJ297559 xref: EMBL:AJ297560 xref: EMBL:BC114432 xref: EMBL:S67334 xref: HGNC:HGNC:8976 xref: UniGene:Hs.239818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001610 ! PK3CB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005322 name: PIK3CG_human def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform gene" [UniProtKB:P48736] xref: EMBL:AC005018 xref: EMBL:AF327656 xref: EMBL:BC035683 xref: EMBL:X83368 xref: HGNC:HGNC:8978 xref: UniGene:Hs.32942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005326 ! PK3CG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005323 name: ZMYND8_human def: "Protein kinase C-binding protein 1 gene" [UniProtKB:Q9ULU4] synonym: "KIAA1125" EXACT [UniProtKB:Q9ULU4] synonym: "PRKCBP1" EXACT [UniProtKB:Q9ULU4] synonym: "RACK7" EXACT [UniProtKB:Q9ULU4] xref: EMBL:AB032951 xref: EMBL:AF233453 xref: EMBL:AF273045 xref: EMBL:AF454056 xref: EMBL:AL031666 xref: EMBL:AL049540 xref: EMBL:AL390212 xref: EMBL:BC030721 xref: EMBL:BX641005 xref: EMBL:DQ082998 xref: EMBL:DQ082999 xref: EMBL:U48251 xref: HGNC:HGNC:9397 xref: UniGene:Hs.446240 xref: UniGene:Hs.658553 xref: UniGene:Hs.668465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005935 ! PKCB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005324 name: PKD2_human def: "Polycystin-2 gene" [UniProtKB:Q13563] xref: EMBL:AF004859 xref: EMBL:AF004860 xref: EMBL:AF004861 xref: EMBL:AF004862 xref: EMBL:AF004863 xref: EMBL:AF004864 xref: EMBL:AF004865 xref: EMBL:AF004866 xref: EMBL:AF004867 xref: EMBL:AF004868 xref: EMBL:AF004869 xref: EMBL:AF004870 xref: EMBL:AF004871 xref: EMBL:AF004872 xref: EMBL:AF004873 xref: EMBL:BC112261 xref: EMBL:BC112263 xref: EMBL:U50928 xref: EMBL:U56813 xref: HGNC:HGNC:9009 xref: UniGene:Hs.181272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001757 ! PKD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005325 name: PLEKHA4_human def: "Pleckstrin homology domain-containing family A member 4 gene" [UniProtKB:Q9H4M7] synonym: "PEPP1" EXACT [UniProtKB:Q9H4M7] xref: EMBL:AY007233 xref: EMBL:BC024157 xref: EMBL:BC033832 xref: EMBL:BC064601 xref: HGNC:HGNC:14339 xref: UniGene:Hs.9469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006216 ! PKHA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005326 name: PLEKHB2_human def: "Pleckstrin homology domain-containing family B member 2 gene" [UniProtKB:Q96CS7] synonym: "EVT2" EXACT [UniProtKB:Q96CS7] xref: EMBL:AK000790 xref: EMBL:BC001428 xref: EMBL:BC013991 xref: EMBL:BC050695 xref: HGNC:HGNC:19236 xref: UniGene:Hs.469944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005569 ! PKHB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005327 name: PLEKHF2_human def: "Pleckstrin homology domain-containing family F member 2 gene" [UniProtKB:Q9H8W4] synonym: "ZFYVE18" EXACT [UniProtKB:Q9H8W4] xref: EMBL:AF434819 xref: EMBL:AK023249 xref: EMBL:AL834473 xref: EMBL:BC011806 xref: HGNC:HGNC:20757 xref: UniGene:Hs.29724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005194 ! PKHF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005328 name: PLEKHO1_human def: "Pleckstrin homology domain-containing family O member 1 gene" [UniProtKB:Q53GL0] synonym: "CKIP1" EXACT [UniProtKB:Q53GL0] synonym: "HQ0024c" EXACT [UniProtKB:Q53GL0] synonym: "OC120" EXACT [UniProtKB:Q53GL0] xref: EMBL:AF073836 xref: EMBL:AF168676 xref: EMBL:AF192912 xref: EMBL:AF217956 xref: EMBL:AF291105 xref: EMBL:AK222921 xref: EMBL:AL358073 xref: EMBL:BC010149 xref: EMBL:BC023533 xref: EMBL:CH471121 xref: HGNC:HGNC:24310 xref: UniGene:Hs.438824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001838 ! PKHO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005329 name: PKN1_human def: "Serine/threonine-protein kinase N1 gene" [UniProtKB:Q16512] synonym: "PKN" EXACT [UniProtKB:Q16512] synonym: "PRK1" EXACT [UniProtKB:Q16512] synonym: "PRKCL1" EXACT [UniProtKB:Q16512] xref: EMBL:BC040061 xref: EMBL:D26181 xref: EMBL:S75546 xref: EMBL:U33053 xref: HGNC:HGNC:9405 xref: UniGene:Hs.466044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006068 ! PKN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005330 name: PKP2_human def: "Plakophilin-2 gene" [UniProtKB:Q99959] xref: EMBL:X97675 xref: HGNC:HGNC:9024 xref: UniGene:Hs.164384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005826 ! PKP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005331 name: JUP_human def: "Junction plakoglobin gene" [UniProtKB:P14923] synonym: "CTNNG" EXACT [UniProtKB:P14923] synonym: "DP3" EXACT [UniProtKB:P14923] xref: EMBL:AF233882 xref: EMBL:AF306723 xref: EMBL:AJ249711 xref: EMBL:AY243535 xref: EMBL:BC000441 xref: EMBL:BC011865 xref: EMBL:CH471152 xref: EMBL:M23410 xref: EMBL:Z68228 xref: HGNC:HGNC:6207 xref: UniGene:Hs.514174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005684 ! PLAK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005332 name: PLAGL1_human def: "Zinc finger protein PLAGL1 gene" [UniProtKB:Q9UM63] synonym: "LOT1" EXACT [UniProtKB:Q9UM63] synonym: "ZAC" EXACT [UniProtKB:Q9UM63] xref: EMBL:AJ006354 xref: EMBL:AJ303119 xref: EMBL:AJ311395 xref: EMBL:AL049844 xref: EMBL:BC074814 xref: EMBL:BC109085 xref: EMBL:BC109086 xref: EMBL:BX537397 xref: EMBL:CH471051 xref: EMBL:U72621 xref: EMBL:U81992 xref: HGNC:HGNC:9046 xref: UniGene:Hs.444975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002231 ! PLAL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005333 name: PLCB1_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 gene" [UniProtKB:Q9NQ66] synonym: "KIAA0581" EXACT [UniProtKB:Q9NQ66] xref: EMBL:AB011153 xref: EMBL:AJ278313 xref: EMBL:AJ278314 xref: EMBL:AK023689 xref: EMBL:AL031683 xref: EMBL:AL034551 xref: EMBL:AL049593 xref: EMBL:AL049632 xref: EMBL:AL050315 xref: EMBL:AL050323 xref: EMBL:AL137267 xref: EMBL:AY004175 xref: EMBL:BC069420 xref: HGNC:HGNC:15917 xref: UniGene:Hs.431173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002151 ! PLCB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005334 name: PLCG1_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 gene" [UniProtKB:P19174] synonym: "PLC1" EXACT [UniProtKB:P19174] xref: EMBL:AL022394 xref: EMBL:CH471077 xref: EMBL:DQ297143 xref: EMBL:M34667 xref: HGNC:HGNC:9065 xref: UniGene:Hs.268177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005610 ! PLCG1_HUMAN relationship: codes_for CCO:B0053714 ! A2A284_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005335 name: PLDN_human def: "Pallidin gene" [UniProtKB:Q9UL45] synonym: "PA" EXACT [UniProtKB:Q9UL45] xref: EMBL:AF080470 xref: EMBL:AK057545 xref: EMBL:BC004819 xref: HGNC:HGNC:8549 xref: UniGene:Hs.7037 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005183 ! PLDN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005336 name: PGF_human def: "Placenta growth factor precursor gene" [UniProtKB:P49763] synonym: "PGFL" EXACT [UniProtKB:P49763] synonym: "PLGF" EXACT [UniProtKB:P49763] xref: EMBL:AC006530 xref: EMBL:BC001422 xref: EMBL:BC007255 xref: EMBL:BC007789 xref: EMBL:S57152 xref: EMBL:S72960 xref: EMBL:X54936 xref: HGNC:HGNC:8893 xref: UniGene:Hs.252820 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001633 ! PLGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005337 name: PLK1_human def: "Serine/threonine-protein kinase PLK1 gene" [UniProtKB:P53350] synonym: "PLK" EXACT [UniProtKB:P53350] xref: EMBL:BC002369 xref: EMBL:BC003002 xref: EMBL:BC014846 xref: EMBL:L19559 xref: EMBL:U01038 xref: EMBL:U78073 xref: EMBL:X73458 xref: EMBL:X75932 xref: EMBL:X90725 xref: HGNC:HGNC:9077 xref: UniGene:Hs.592049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001663 ! PLK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005338 name: PLK2_human def: "Serine/threonine-protein kinase PLK2 gene" [UniProtKB:Q9NYY3] synonym: "SNK" EXACT [UniProtKB:Q9NYY3] xref: EMBL:AF059617 xref: EMBL:AF223574 xref: EMBL:BC013879 xref: EMBL:U85755 xref: HGNC:HGNC:19699 xref: UniGene:Hs.398157 xref: UniGene:Hs.658132 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002179 ! PLK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005340 name: PLK4_human def: "Serine/threonine-protein kinase PLK4 gene" [UniProtKB:O00444] synonym: "SAK" EXACT [UniProtKB:O00444] synonym: "STK18" EXACT [UniProtKB:O00444] xref: EMBL:AB006972 xref: EMBL:BC036023 xref: EMBL:Y13115 xref: HGNC:HGNC:11397 xref: UniGene:Hs.172052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001348 ! PLK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005341 name: PLXNB2_human def: "Plexin-B2 precursor gene" [UniProtKB:O15031] synonym: "KIAA0315" EXACT [UniProtKB:O15031] xref: EMBL:AB002313 xref: EMBL:AL022328 xref: EMBL:BC004542 xref: EMBL:BC110366 xref: EMBL:BT006887 xref: EMBL:BX649592 xref: HGNC:HGNC:9104 xref: UniGene:Hs.3989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006292 ! PLXB2_HUMAN relationship: codes_for CCO:B0053938 ! A6QRG9_HUMAN relationship: codes_for CCO:B0053939 ! A6QRH2_HUMAN relationship: codes_for CCO:B0056231 ! Q2TBE4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005342 name: PLXNB3_human def: "Plexin-B3 precursor gene" [UniProtKB:Q9ULL4] synonym: "KIAA1206" EXACT [UniProtKB:Q9ULL4] synonym: "PLXN6" EXACT [UniProtKB:Q9ULL4] xref: EMBL:AB033032 xref: EMBL:AF149019 xref: HGNC:HGNC:9105 xref: UniGene:Hs.632833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005547 ! PLXB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005343 name: PMF1_human def: "Polyamine-modulated factor 1 gene" [UniProtKB:Q6P1K2] xref: EMBL:AF141308 xref: EMBL:AF141309 xref: EMBL:AF141310 xref: EMBL:AL080101 xref: EMBL:AL135927 xref: EMBL:BC033656 xref: EMBL:BC050735 xref: EMBL:BC056417 xref: EMBL:BC065031 xref: HGNC:HGNC:9112 xref: UniGene:Hs.530479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001912 ! PMF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005344 name: PML_human def: "Probable transcription factor PML gene" [UniProtKB:P29590] synonym: "MYL" EXACT [UniProtKB:P29590] synonym: "RNF71" EXACT [UniProtKB:P29590] synonym: "TRIM19" EXACT [UniProtKB:P29590] xref: EMBL:AB067754 xref: EMBL:AC013486 xref: EMBL:AC108137 xref: EMBL:AF230401 xref: EMBL:BC000080 xref: EMBL:BC020994 xref: EMBL:BT009911 xref: EMBL:M73778 xref: EMBL:M79462 xref: EMBL:M79463 xref: EMBL:M79464 xref: EMBL:M80185 xref: EMBL:S50913 xref: EMBL:X63131 xref: EMBL:X64800 xref: HGNC:HGNC:9113 xref: UniGene:Hs.526464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001570 ! PML_HUMAN relationship: codes_for CCO:B0005644 ! Q9BWP7_HUMAN relationship: codes_for CCO:B0021348 ! Q15959_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005345 name: PMS1_human def: "PMS1 protein homolog 1 gene" [UniProtKB:P54277] synonym: "PMSL1" EXACT [UniProtKB:P54277] xref: EMBL:AB102874 xref: EMBL:AY267352 xref: EMBL:AY540750 xref: EMBL:BC084548 xref: EMBL:U13695 xref: HGNC:HGNC:9121 xref: UniGene:Hs.111749 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001668 ! PMS1_HUMAN relationship: codes_for CCO:B0020445 ! Q5XG96_HUMAN relationship: codes_for CCO:B0020446 ! Q5FBZ4_HUMAN relationship: codes_for CCO:B0020453 ! Q3BDU4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005346 name: PMS2_human def: "Mismatch repair endonuclease PMS2 gene" [UniProtKB:P54278] synonym: "PMSL2" EXACT [UniProtKB:P54278] xref: EMBL:AB103082 xref: EMBL:AB103083 xref: EMBL:AB103085 xref: EMBL:AB103086 xref: EMBL:AC005995 xref: EMBL:BC093921 xref: EMBL:U13696 xref: EMBL:U14658 xref: HGNC:HGNC:9122 xref: UniGene:Hs.632637 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001669 ! PMS2_HUMAN relationship: codes_for CCO:B0025458 ! Q5FBW8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005347 name: PKMYT1_human def: "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase gene" [UniProtKB:Q99640] synonym: "MYT1" EXACT [UniProtKB:Q99640] xref: EMBL:AC004233 xref: EMBL:AC004235 xref: EMBL:AF014118 xref: EMBL:AF549406 xref: EMBL:AL713779 xref: EMBL:U56816 xref: HGNC:HGNC:29650 xref: UniGene:Hs.77783 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002078 ! PMYT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005348 name: PNMA1_human def: "Paraneoplastic antigen Ma1 gene" [UniProtKB:Q8ND90] synonym: "MA1" EXACT [UniProtKB:Q8ND90] xref: EMBL:AF037364 xref: EMBL:AF320308 xref: EMBL:AL834327 xref: EMBL:BC039577 xref: HGNC:HGNC:9158 xref: UniGene:Hs.194709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005877 ! PNMA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005349 name: PNO1_human def: "RNA-binding protein PNO1 gene" [UniProtKB:Q9NRX1] xref: EMBL:AC017083 xref: EMBL:AF164799 xref: EMBL:AF349314 xref: EMBL:AK223118 xref: EMBL:BC008304 xref: EMBL:BC018152 xref: HGNC:HGNC:32790 xref: UniGene:Hs.262858 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006240 ! PNO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005350 name: NP_human def: "Purine nucleoside phosphorylase gene" [UniProtKB:P00491] synonym: "PNP" EXACT [UniProtKB:P00491] xref: EMBL:AY817667 xref: EMBL:BC104206 xref: EMBL:BC104207 xref: EMBL:BC106074 xref: EMBL:CR407607 xref: EMBL:J02672 xref: EMBL:M13951 xref: EMBL:M13952 xref: EMBL:M13953 xref: EMBL:X00737 xref: HGNC:HGNC:7892 xref: UniGene:Hs.75514 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006097 ! PNPH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005351 name: POU2F1_human def: "POU domain, class 2, transcription factor 1 gene" [UniProtKB:P14859] synonym: "OCT1" EXACT [UniProtKB:P14859] synonym: "OTF1" EXACT [UniProtKB:P14859] xref: EMBL:AL136984 xref: EMBL:AY113189 xref: EMBL:BC001664 xref: EMBL:BC003571 xref: EMBL:BC007388 xref: EMBL:BC052274 xref: EMBL:X13403 xref: HGNC:HGNC:9212 xref: UniGene:Hs.493649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006069 ! PO2F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005352 name: POU2F3_human def: "POU domain, class 2, transcription factor 3 gene" [UniProtKB:Q9UKI9] synonym: "OTF11" EXACT [UniProtKB:Q9UKI9] synonym: "PLA1" EXACT [UniProtKB:Q9UKI9] xref: EMBL:AF133895 xref: EMBL:AF162278 xref: EMBL:AJ012214 xref: EMBL:BC101649 xref: HGNC:HGNC:19864 xref: UniGene:Hs.227115 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006049 ! PO2F3_HUMAN relationship: codes_for CCO:B0056263 ! Q3MIY3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005353 name: POU3F3_human def: "POU domain, class 3, transcription factor 3 gene" [UniProtKB:P20264] synonym: "BRN1" EXACT [UniProtKB:P20264] synonym: "OTF8" EXACT [UniProtKB:P20264] xref: EMBL:AB001835 xref: HGNC:HGNC:9216 xref: UniGene:Hs.673855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006341 ! PO3F3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005354 name: POLS_human def: "DNA polymerase sigma gene" [UniProtKB:Q5XG87] synonym: "TRF4" EXACT [UniProtKB:Q5XG87] xref: EMBL:AB005754 xref: EMBL:AF089896 xref: EMBL:AY623114 xref: EMBL:BC084567 xref: EMBL:BC117137 xref: EMBL:BC126106 xref: HGNC:HGNC:16705 xref: UniGene:Hs.481542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001902 ! POLS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005355 name: POT1_human def: "Protection of telomeres protein 1 gene" [UniProtKB:Q9NUX5] xref: EMBL:AC004925 xref: EMBL:AC096665 xref: EMBL:AC110791 xref: EMBL:AK001230 xref: EMBL:AK001935 xref: EMBL:AK022580 xref: EMBL:AK026234 xref: EMBL:AL050120 xref: EMBL:BC002923 xref: HGNC:HGNC:17284 xref: UniGene:Hs.31968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005503 ! POTE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005356 name: PPP1CA_human def: "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit gene" [UniProtKB:P62136] synonym: "PPP1A" EXACT [UniProtKB:P62136] xref: EMBL:BC001888 xref: EMBL:BC004482 xref: EMBL:BC008010 xref: EMBL:BT006629 xref: EMBL:J04759 xref: EMBL:M63960 xref: EMBL:X70848 xref: HGNC:HGNC:9281 xref: UniGene:Hs.183994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001688 ! PP1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005357 name: PPP1CB_human def: "Serine/threonine-protein phosphatase PP1-beta catalytic subunit gene" [UniProtKB:P62140] xref: EMBL:AC097724 xref: EMBL:AF092905 xref: EMBL:BC002697 xref: EMBL:BC012045 xref: EMBL:BT019744 xref: EMBL:CR542263 xref: EMBL:CR542285 xref: EMBL:U10998 xref: EMBL:U10999 xref: EMBL:U11000 xref: EMBL:U11001 xref: EMBL:U11002 xref: EMBL:U11003 xref: EMBL:U11004 xref: EMBL:U11005 xref: EMBL:X80910 xref: HGNC:HGNC:9282 xref: UniGene:Hs.591571 xref: UniGene:Hs.705383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001689 ! PP1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005358 name: PPP1CC_human def: "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit gene" [UniProtKB:P36873] xref: EMBL:BC014073 xref: EMBL:L07395 xref: EMBL:X74008 xref: HGNC:HGNC:9283 xref: UniGene:Hs.79081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001596 ! PP1G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005359 name: PPP2CA_human def: "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform gene" [UniProtKB:P67775] xref: EMBL:BC000400 xref: EMBL:BC002657 xref: EMBL:BC019275 xref: EMBL:BC031696 xref: EMBL:J03804 xref: EMBL:M60483 xref: EMBL:X12646 xref: HGNC:HGNC:9299 xref: UniGene:Hs.483408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001697 ! PP2AA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005360 name: PPP3CB_human def: "Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform gene" [UniProtKB:P16298] synonym: "CALNA2" EXACT [UniProtKB:P16298] synonym: "CALNB" EXACT [UniProtKB:P16298] synonym: "CNA2" EXACT [UniProtKB:P16298] xref: EMBL:AJ488506 xref: EMBL:AL353731 xref: EMBL:AL359074 xref: EMBL:CH471083 xref: EMBL:M29550 xref: EMBL:M29551 xref: HGNC:HGNC:9315 xref: UniGene:Hs.500067 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001527 ! PP2BB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005362 name: PPARG_human def: "Peroxisome proliferator-activated receptor gamma gene" [UniProtKB:P37231] synonym: "NR1C3" EXACT [UniProtKB:P37231] xref: EMBL:AB005526 xref: EMBL:AB097931 xref: EMBL:AB107271 xref: EMBL:AJ563370 xref: EMBL:AY157024 xref: EMBL:BC006811 xref: EMBL:BT007281 xref: EMBL:D83233 xref: EMBL:L40904 xref: EMBL:U63415 xref: EMBL:U79012 xref: EMBL:X90563 xref: HGNC:HGNC:9236 xref: UniGene:Hs.162646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005616 ! PPARG_HUMAN relationship: codes_for CCO:B0056334 ! Q4W4C6_HUMAN relationship: codes_for CCO:B0056837 ! Q6L9M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005363 name: PPAPDC1B_human def: "Phosphatidic acid phosphatase type 2 domain-containing protein 1B gene" [UniProtKB:Q8NEB5] synonym: "HTPAP" EXACT [UniProtKB:Q8NEB5] xref: EMBL:AF212238 xref: EMBL:BC033025 xref: EMBL:BC106014 xref: HGNC:HGNC:25026 xref: UniGene:Hs.567619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001978 ! PPC1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005364 name: PPIA_human def: "Peptidyl-prolyl cis-trans isomerase A gene" [UniProtKB:P62937] synonym: "CYPA" EXACT [UniProtKB:P62937] xref: EMBL:AY739283 xref: EMBL:BC000689 xref: EMBL:BC003026 xref: EMBL:BC005320 xref: EMBL:BC005982 xref: EMBL:BC007104 xref: EMBL:BC013915 xref: EMBL:BC073992 xref: EMBL:BC106030 xref: EMBL:CR456707 xref: EMBL:X52851 xref: EMBL:Y00052 xref: HGNC:HGNC:9253 xref: UniGene:Hs.356331 xref: UniGene:Hs.598115 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006072 ! PPIA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005365 name: PPIB_human def: "Peptidyl-prolyl cis-trans isomerase B precursor gene" [UniProtKB:P23284] synonym: "CYPB" EXACT [UniProtKB:P23284] xref: EMBL:AC100840 xref: EMBL:AK291149 xref: EMBL:AY962310 xref: EMBL:BC001125 xref: EMBL:BC008848 xref: EMBL:BC020800 xref: EMBL:BC032138 xref: EMBL:CH471082 xref: EMBL:CR456829 xref: EMBL:M60457 xref: EMBL:M60857 xref: EMBL:M63573 xref: HGNC:HGNC:9255 xref: UniGene:Hs.434937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006327 ! PPIB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005366 name: PPM1A_human def: "Protein phosphatase 1A gene" [UniProtKB:P35813] synonym: "PPPM1A" EXACT [UniProtKB:P35813] xref: EMBL:AF070670 xref: EMBL:BC026691 xref: EMBL:BC063243 xref: EMBL:S87759 xref: HGNC:HGNC:9275 xref: UniGene:Hs.592298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005649 ! PPM1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005367 name: PPM1D_human def: "Protein phosphatase 1D gene" [UniProtKB:O15297] synonym: "WIP1" EXACT [UniProtKB:O15297] xref: EMBL:BC016480 xref: EMBL:U78305 xref: HGNC:HGNC:9277 xref: UniGene:Hs.591184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001372 ! PPM1D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005368 name: PPM1G_human def: "Protein phosphatase 1G gene" [UniProtKB:O15355] synonym: "PPM1C" EXACT [UniProtKB:O15355] xref: EMBL:BC000057 xref: EMBL:BC022061 xref: EMBL:Y13936 xref: HGNC:HGNC:9278 xref: UniGene:Hs.699225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001375 ! PPM1G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005369 name: PPP5C_human def: "Serine/threonine-protein phosphatase 5 gene" [UniProtKB:P53041] synonym: "PPP5" EXACT [UniProtKB:P53041] xref: EMBL:AC007193 xref: EMBL:BC001970 xref: EMBL:U25174 xref: EMBL:X89416 xref: EMBL:X92121 xref: HGNC:HGNC:9322 xref: UniGene:Hs.654604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001662 ! PPP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005370 name: PPP6C_human def: "Serine/threonine-protein phosphatase 6 gene" [UniProtKB:O00743] synonym: "PPP6" EXACT [UniProtKB:O00743] xref: EMBL:AF035158 xref: EMBL:AL445930 xref: EMBL:BC006990 xref: EMBL:BT019708 xref: EMBL:CH471090 xref: EMBL:X92972 xref: HGNC:HGNC:9323 xref: UniGene:Hs.584019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001353 ! PPP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005371 name: PQBP1_human def: "Polyglutamine-binding protein 1 gene" [UniProtKB:O60828] synonym: "JM26" EXACT [UniProtKB:O60828] synonym: "NPW38" EXACT [UniProtKB:O60828] xref: EMBL:AB016533 xref: EMBL:AB041832 xref: EMBL:AB041833 xref: EMBL:AB041834 xref: EMBL:AB041835 xref: EMBL:AB041836 xref: EMBL:AJ005893 xref: EMBL:AJ242829 xref: EMBL:AJ973593 xref: EMBL:AJ973594 xref: EMBL:AJ973595 xref: EMBL:AJ973596 xref: EMBL:AJ973597 xref: EMBL:AJ973598 xref: EMBL:AJ973599 xref: EMBL:AJ973600 xref: EMBL:AJ973601 xref: EMBL:AJ973602 xref: EMBL:AJ973603 xref: EMBL:AJ973605 xref: EMBL:AJ973606 xref: EMBL:AJ973607 xref: EMBL:BC012358 xref: HGNC:HGNC:9330 xref: UniGene:Hs.534384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006218 ! PQBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005372 name: PRIC285_human def: "Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein gene" [UniProtKB:Q9BYK8] synonym: "KIAA1769" EXACT [UniProtKB:Q9BYK8] xref: EMBL:AB051556 xref: EMBL:AB201715 xref: EMBL:AF517673 xref: EMBL:AK055611 xref: EMBL:AK074171 xref: EMBL:AL121829 xref: UniGene:Hs.517180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006035 ! PR285_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005373 name: PRC1_human def: "Protein regulator of cytokinesis 1 gene" [UniProtKB:O43663] xref: EMBL:AC068831 xref: EMBL:AF044588 xref: EMBL:AK297117 xref: EMBL:BC003138 xref: EMBL:BC005140 xref: HGNC:HGNC:9341 xref: UniGene:Hs.567385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001394 ! PRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005374 name: PPARGC1A_human def: "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha gene" [UniProtKB:Q9UBK2] synonym: "LEM6" EXACT [UniProtKB:Q9UBK2] synonym: "PGC1" EXACT [UniProtKB:Q9UBK2] synonym: "PGC1A" EXACT [UniProtKB:Q9UBK2] synonym: "PPARGC1" EXACT [UniProtKB:Q9UBK2] xref: EMBL:AF106698 xref: EMBL:AF108193 xref: EMBL:AF108194 xref: EMBL:AF108195 xref: EMBL:AF108196 xref: EMBL:AF108197 xref: EMBL:AF108198 xref: EMBL:AF108199 xref: EMBL:AF108200 xref: EMBL:AF108201 xref: EMBL:AF108202 xref: EMBL:AF108203 xref: EMBL:AF108204 xref: EMBL:AF108205 xref: EMBL:AF159714 xref: EMBL:AF186379 xref: HGNC:HGNC:9237 xref: UniGene:Hs.527078 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006031 ! PRGC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005375 name: PRIM1_human def: "DNA primase small subunit gene" [UniProtKB:P49642] xref: EMBL:BC005266 xref: EMBL:U89689 xref: EMBL:X74330 xref: HGNC:HGNC:9369 xref: UniGene:Hs.534339 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005507 ! PRI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005377 name: PARK2_human def: "E3 ubiquitin-protein ligase parkin gene" [UniProtKB:O60260] synonym: "PRKN" EXACT [UniProtKB:O60260] xref: EMBL:AB009973 xref: EMBL:AF381282 xref: EMBL:AF381283 xref: EMBL:AF381286 xref: EMBL:AL035697 xref: EMBL:AL132982 xref: EMBL:AL445215 xref: EMBL:AP000886 xref: EMBL:AP000887 xref: EMBL:AP001576 xref: EMBL:AP001577 xref: EMBL:AP001578 xref: EMBL:AP003699 xref: EMBL:AY564225 xref: EMBL:BC022014 xref: HGNC:HGNC:8607 xref: UniGene:Hs.132954 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006227 ! PRKN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005378 name: PRM2_human def: "Protamine-2 gene" [UniProtKB:P04554] xref: EMBL:AF215713 xref: EMBL:BC005303 xref: EMBL:BC066338 xref: EMBL:M60332 xref: EMBL:U15422 xref: EMBL:X07862 xref: EMBL:Z46940 xref: HGNC:HGNC:9448 xref: UniGene:Hs.2324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001482 ! PRM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005379 name: PRM3_human def: "Protamine-3 gene" [UniProtKB:Q9NNZ6] xref: EMBL:Z46940 xref: HGNC:HGNC:13732 xref: UniGene:Hs.259636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002149 ! PRM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005380 name: PFN1_human def: "Profilin-1 gene" [UniProtKB:P07737] xref: EMBL:BC002475 xref: EMBL:BC006768 xref: EMBL:BC013439 xref: EMBL:BC015164 xref: EMBL:BC057828 xref: EMBL:J03191 xref: HGNC:HGNC:8881 xref: UniGene:Hs.494691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006154 ! PROF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005381 name: PFN2_human def: "Profilin-2 gene" [UniProtKB:P35080] xref: EMBL:AF228738 xref: EMBL:BC002964 xref: EMBL:BC018049 xref: EMBL:BC043646 xref: EMBL:L10678 xref: HGNC:HGNC:8882 xref: UniGene:Hs.91747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006155 ! PROF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005382 name: PROK1_human def: "Prokineticin-1 precursor gene" [UniProtKB:P58294] synonym: "UNQ600/PRO1186" EXACT [UniProtKB:P58294] xref: EMBL:AF333024 xref: EMBL:AL358215 xref: EMBL:AL390797 xref: EMBL:AY029225 xref: EMBL:AY358683 xref: EMBL:CH471122 xref: HGNC:HGNC:18454 xref: UniGene:Hs.514793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001683 ! PROK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005384 name: PSMC1_human def: "26S protease regulatory subunit 4 gene" [UniProtKB:P62191] xref: EMBL:BC000512 xref: EMBL:BC016368 xref: EMBL:BC073818 xref: EMBL:CR457044 xref: EMBL:L02426 xref: HGNC:HGNC:9547 xref: UniGene:Hs.356654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005314 ! PRS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005385 name: PSMA1_human def: "Proteasome subunit alpha type-1 gene" [UniProtKB:P25786] synonym: "PROS30" EXACT [UniProtKB:P25786] synonym: "PSC2" EXACT [UniProtKB:P25786] xref: EMBL:BC002577 xref: EMBL:BC005932 xref: EMBL:BC008472 xref: EMBL:BC009576 xref: EMBL:BC015105 xref: EMBL:BC015356 xref: EMBL:BC022372 xref: EMBL:D00759 xref: EMBL:M64992 xref: EMBL:X61969 xref: HGNC:HGNC:9530 xref: UniGene:Hs.102798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005233 ! PSA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005386 name: PSMA3_human def: "Proteasome subunit alpha type-3 gene" [UniProtKB:P25788] synonym: "PSC8" EXACT [UniProtKB:P25788] xref: EMBL:BC005265 xref: EMBL:BC029402 xref: EMBL:BC038990 xref: EMBL:BT006711 xref: EMBL:BT019715 xref: EMBL:D00762 xref: HGNC:HGNC:9532 xref: UniGene:Hs.558799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005991 ! PSA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005387 name: PSMB10_human def: "Proteasome subunit beta type-10 precursor gene" [UniProtKB:P40306] synonym: "MECL1" EXACT [UniProtKB:P40306] xref: EMBL:BC017198 xref: EMBL:BC052369 xref: EMBL:BT019723 xref: EMBL:BT019724 xref: EMBL:X71874 xref: EMBL:Y13640 xref: HGNC:HGNC:9538 xref: UniGene:Hs.9661 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006219 ! PSB10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005388 name: PSMD11_human def: "26S proteasome non-ATPase regulatory subunit 11 gene" [UniProtKB:O00231] xref: EMBL:AB003102 xref: EMBL:AF001212 xref: EMBL:BC000437 xref: EMBL:BC004430 xref: HGNC:HGNC:9556 xref: UniGene:Hs.655396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006103 ! PSD11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005389 name: PSG9_human def: "Pregnancy-specific beta-1-glycoprotein 9 precursor gene" [UniProtKB:Q00887] synonym: "PSG11" EXACT [UniProtKB:Q00887] xref: EMBL:AC005392 xref: EMBL:AF106557 xref: EMBL:AF106558 xref: EMBL:BC020759 xref: EMBL:M34421 xref: EMBL:M34481 xref: EMBL:M38046 xref: EMBL:M38243 xref: EMBL:M58591 xref: EMBL:U04325 xref: EMBL:X17610 xref: HGNC:HGNC:9526 xref: UniGene:Hs.502092 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006157 ! PSG9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005390 name: PSMD1_human def: "26S proteasome non-ATPase regulatory subunit 1 gene" [UniProtKB:Q99460] xref: EMBL:AC009407 xref: EMBL:BC001053 xref: EMBL:BC014013 xref: EMBL:BC039845 xref: EMBL:BC047897 xref: EMBL:BC064398 xref: EMBL:BC073833 xref: EMBL:BC094720 xref: EMBL:BC112344 xref: EMBL:BC114434 xref: EMBL:D44466 xref: HGNC:HGNC:9554 xref: UniGene:Hs.3887 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002066 ! PSMD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005391 name: PSMD2_human def: "26S proteasome non-ATPase regulatory subunit 2 gene" [UniProtKB:Q13200] synonym: "TRAP2" EXACT [UniProtKB:Q13200] xref: EMBL:BC002368 xref: EMBL:BC002997 xref: EMBL:BC007897 xref: EMBL:D78151 xref: EMBL:U12596 xref: EMBL:X86446 xref: HGNC:HGNC:9559 xref: UniGene:Hs.518464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001745 ! PSMD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005392 name: PSMD8_human def: "26S proteasome non-ATPase regulatory subunit 8 gene" [UniProtKB:P48556] xref: EMBL:AC005789 xref: EMBL:BC001164 xref: EMBL:D38047 xref: HGNC:HGNC:9566 xref: UniGene:Hs.78466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001625 ! PSMD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005393 name: PSME1_human def: "Proteasome activator complex subunit 1 gene" [UniProtKB:Q06323] synonym: "IFI5111" EXACT [UniProtKB:Q06323] xref: EMBL:AB007137 xref: EMBL:AF078829 xref: EMBL:BC000352 xref: EMBL:BC007503 xref: EMBL:BT019337 xref: EMBL:L07633 xref: EMBL:U10360 xref: HGNC:HGNC:9568 xref: UniGene:Hs.75348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006215 ! PSME1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005394 name: PSEN1_human def: "Presenilin-1 gene" [UniProtKB:P49768] synonym: "AD3" EXACT [UniProtKB:P49768] synonym: "PS1" EXACT [UniProtKB:P49768] synonym: "PSNL1" EXACT [UniProtKB:P49768] xref: EMBL:AC004858 xref: EMBL:AF109907 xref: EMBL:AF416717 xref: EMBL:AJ008005 xref: EMBL:BC011729 xref: EMBL:D84149 xref: EMBL:L42110 xref: EMBL:L76517 xref: EMBL:L76519 xref: EMBL:L76520 xref: EMBL:L76521 xref: EMBL:L76522 xref: EMBL:L76523 xref: EMBL:L76524 xref: EMBL:L76525 xref: EMBL:L76526 xref: EMBL:L76527 xref: EMBL:L76528 xref: EMBL:U40379 xref: EMBL:U40380 xref: HGNC:HGNC:9508 xref: UniGene:Hs.592324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005716 ! PSN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005395 name: PTCH1_human def: "Protein patched homolog 1 gene" [UniProtKB:Q13635] synonym: "PTCH" EXACT [UniProtKB:Q13635] xref: EMBL:AL161729 xref: EMBL:U43148 xref: EMBL:U59464 xref: HGNC:HGNC:9585 xref: UniGene:Hs.494538 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001765 ! PTC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005396 name: PTEN_human def: "Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN gene" [UniProtKB:P60484] synonym: "MMAC1" EXACT [UniProtKB:P60484] synonym: "TEP1" EXACT [UniProtKB:P60484] xref: EMBL:AF000726 xref: EMBL:AF000727 xref: EMBL:AF000728 xref: EMBL:AF000729 xref: EMBL:AF000730 xref: EMBL:AF000731 xref: EMBL:AF000732 xref: EMBL:AF000733 xref: EMBL:AF000734 xref: EMBL:AF067844 xref: EMBL:AF143312 xref: EMBL:AF143313 xref: EMBL:AF143314 xref: EMBL:AF143315 xref: EMBL:BC005821 xref: EMBL:CR450306 xref: EMBL:DQ073384 xref: EMBL:U92436 xref: EMBL:U93051 xref: EMBL:U96180 xref: HGNC:HGNC:9588 xref: UniGene:Hs.500466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001685 ! PTEN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005398 name: PTMS_human def: "Parathymosin gene" [UniProtKB:P20962] xref: EMBL:M24398 xref: HGNC:HGNC:9629 xref: UniGene:Hs.504613 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001539 ! PTMS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005399 name: PTPN6_human def: "Tyrosine-protein phosphatase non-receptor type 6 gene" [UniProtKB:P29350] synonym: "HCP" EXACT [UniProtKB:P29350] synonym: "PTP1C" EXACT [UniProtKB:P29350] xref: EMBL:AB079851 xref: EMBL:BC002523 xref: EMBL:BC007667 xref: EMBL:M74903 xref: EMBL:M77273 xref: EMBL:U15528 xref: EMBL:U15529 xref: EMBL:U15530 xref: EMBL:U15531 xref: EMBL:U15532 xref: EMBL:U15533 xref: EMBL:U15534 xref: EMBL:U15535 xref: EMBL:U15536 xref: EMBL:U15537 xref: EMBL:U47924 xref: EMBL:X62055 xref: HGNC:HGNC:9658 xref: UniGene:Hs.63489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005608 ! PTN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005400 name: PTN_human def: "Pleiotrophin precursor gene" [UniProtKB:P21246] synonym: "HBNF1" EXACT [UniProtKB:P21246] synonym: "NEGF1" EXACT [UniProtKB:P21246] xref: EMBL:AB004306 xref: EMBL:BC005916 xref: EMBL:D90226 xref: EMBL:M57399 xref: EMBL:S50394 xref: EMBL:S50405 xref: EMBL:S50408 xref: EMBL:S50409 xref: EMBL:S59641 xref: EMBL:S60110 xref: EMBL:S60111 xref: EMBL:S60736 xref: EMBL:X52946 xref: HGNC:HGNC:9630 xref: UniGene:Hs.371249 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001541 ! PTN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005401 name: PTOV1_human def: "Prostate tumor overexpressed gene 1 protein gene" [UniProtKB:Q86YD1] synonym: "ACID2" EXACT [UniProtKB:Q86YD1] synonym: "PP642" EXACT [UniProtKB:Q86YD1] synonym: "UNQ6127/PRO20092" EXACT [UniProtKB:Q86YD1] xref: EMBL:AF218026 xref: EMBL:AF238381 xref: EMBL:AJ617480 xref: EMBL:AY358168 xref: EMBL:BC015172 xref: EMBL:BC042921 xref: EMBL:CH471177 xref: HGNC:HGNC:9632 xref: UniGene:Hs.587979 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006294 ! PTOV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005402 name: PTPRS_human def: "Receptor-type tyrosine-protein phosphatase S precursor gene" [UniProtKB:Q13332] xref: EMBL:AC005335 xref: EMBL:AC005338 xref: EMBL:AC005788 xref: EMBL:AC005790 xref: EMBL:AC118535 xref: EMBL:S78080 xref: EMBL:U35234 xref: EMBL:U40317 xref: HGNC:HGNC:9681 xref: UniGene:Hs.700666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006104 ! PTPRS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005403 name: PTTG1_human def: "Securin gene" [UniProtKB:O95997] synonym: "EAP1" EXACT [UniProtKB:O95997] synonym: "PTTG" EXACT [UniProtKB:O95997] synonym: "TUTR1" EXACT [UniProtKB:O95997] xref: EMBL:AF075242 xref: EMBL:AF095287 xref: EMBL:AF167560 xref: EMBL:AF167561 xref: EMBL:AF167562 xref: EMBL:AF167563 xref: EMBL:AF167564 xref: EMBL:AJ223953 xref: HGNC:HGNC:9690 xref: UniGene:Hs.350966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001457 ! PTTG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005404 name: PYGO2_human def: "Pygopus homolog 2 gene" [UniProtKB:Q9BRQ0] synonym: "PP7910" EXACT [UniProtKB:Q9BRQ0] xref: EMBL:AF289598 xref: EMBL:AF457208 xref: EMBL:BC006132 xref: EMBL:BC013725 xref: EMBL:BC032099 xref: HGNC:HGNC:30257 xref: UniGene:Hs.533597 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006062 ! PYGO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005405 name: KIAA1009_human def: "Protein QN1 homolog gene" [UniProtKB:Q5TB80] synonym: "C6orf84" EXACT [UniProtKB:Q5TB80] synonym: "QN1" EXACT [UniProtKB:Q5TB80] xref: EMBL:AB023226 xref: EMBL:AL138742 xref: EMBL:BC063632 xref: HGNC:HGNC:21107 xref: UniGene:Hs.485865 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001883 ! QN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005406 name: RAD51L1_human def: "DNA repair protein RAD51 homolog 2 gene" [UniProtKB:O15315] synonym: "RAD51B" EXACT [UniProtKB:O15315] synonym: "REC2" EXACT [UniProtKB:O15315] xref: EMBL:AC004518 xref: EMBL:AY138857 xref: EMBL:AY138858 xref: EMBL:AY138859 xref: EMBL:BC030219 xref: EMBL:BX161515 xref: EMBL:BX248061 xref: EMBL:BX248766 xref: EMBL:DQ160197 xref: EMBL:U84138 xref: EMBL:U92074 xref: EMBL:Y15571 xref: HGNC:HGNC:9822 xref: UniGene:Hs.172587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001373 ! RA51B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005407 name: RAD51L3_human def: "DNA repair protein RAD51 homolog 4 gene" [UniProtKB:O75771] synonym: "RAD51D" EXACT [UniProtKB:O75771] xref: EMBL:AB013341 xref: EMBL:AB016223 xref: EMBL:AB016224 xref: EMBL:AB016225 xref: EMBL:AB018360 xref: EMBL:AB018361 xref: EMBL:AB018362 xref: EMBL:AB018363 xref: EMBL:AB020412 xref: EMBL:AF034956 xref: EMBL:AL117459 xref: EMBL:AY623116 xref: EMBL:BC014422 xref: EMBL:Y15572 xref: HGNC:HGNC:9823 xref: UniGene:Hs.631757 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001434 ! RA51D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005408 name: RAD54B_human def: "DNA repair and recombination protein RAD54B gene" [UniProtKB:Q9Y620] xref: EMBL:AF112481 xref: EMBL:BC001965 xref: HGNC:HGNC:17228 xref: UniGene:Hs.30561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002260 ! RA54B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005409 name: RAB1A_human def: "Ras-related protein Rab-1A gene" [UniProtKB:P62820] synonym: "RAB1" EXACT [UniProtKB:P62820] xref: EMBL:AF498929 xref: EMBL:AK055927 xref: EMBL:AL050268 xref: EMBL:BC000905 xref: EMBL:BX571747 xref: EMBL:M28209 xref: HGNC:HGNC:9758 xref: UniGene:Hs.310645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006222 ! RAB1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005410 name: RAB4A_human def: "Ras-related protein Rab-4A gene" [UniProtKB:P20338] synonym: "RAB4" EXACT [UniProtKB:P20338] xref: EMBL:AF498934 xref: EMBL:AK313807 xref: EMBL:AL117350 xref: EMBL:AL162595 xref: EMBL:AY585832 xref: EMBL:BC002438 xref: EMBL:BC004309 xref: EMBL:CH471098 xref: EMBL:M28211 xref: HGNC:HGNC:9781 xref: UniGene:Hs.296169 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006295 ! RAB4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005411 name: RAC1_human def: "Ras-related C3 botulinum toxin substrate 1 precursor gene" [UniProtKB:P63000] synonym: "MIG5" EXACT [UniProtKB:P63000] xref: EMBL:AC009412 xref: EMBL:AF136373 xref: EMBL:AF498964 xref: EMBL:AJ132694 xref: EMBL:AJ132695 xref: EMBL:AY279384 xref: EMBL:BC004247 xref: EMBL:BC050687 xref: EMBL:BC107748 xref: EMBL:BT007121 xref: EMBL:CH236963 xref: EMBL:CH878731 xref: EMBL:DQ165078 xref: EMBL:M29870 xref: EMBL:M31467 xref: HGNC:HGNC:9801 xref: UniGene:Hs.413812 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005337 ! RAC1_HUMAN relationship: codes_for CCO:B0053761 ! A4D2P2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005412 name: RAD17_human def: "Cell cycle checkpoint protein RAD17 gene" [UniProtKB:O75943] synonym: "R24L" EXACT [UniProtKB:O75943] xref: EMBL:AF017748 xref: EMBL:AF076838 xref: EMBL:AF085736 xref: EMBL:AF098533 xref: EMBL:AF098534 xref: EMBL:AF112263 xref: EMBL:AF126424 xref: EMBL:AJ001642 xref: EMBL:AJ004977 xref: EMBL:AJ131296 xref: EMBL:AJ131297 xref: EMBL:AJ131298 xref: EMBL:AJ131299 xref: EMBL:AJ131300 xref: EMBL:AJ131301 xref: EMBL:AJ131302 xref: EMBL:AJ131303 xref: EMBL:AJ131304 xref: EMBL:AJ131305 xref: EMBL:AJ131306 xref: EMBL:AJ131307 xref: EMBL:AJ131308 xref: EMBL:AL122068 xref: EMBL:AY612854 xref: EMBL:BC032304 xref: EMBL:BX537441 xref: HGNC:HGNC:9807 xref: UniGene:Hs.16184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001441 ! RAD17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005413 name: RAD1_human def: "Cell cycle checkpoint protein RAD1 gene" [UniProtKB:O60671] synonym: "REC1" EXACT [UniProtKB:O60671] xref: EMBL:AB183821 xref: EMBL:AB183822 xref: EMBL:AF011905 xref: EMBL:AF030933 xref: EMBL:AF058392 xref: EMBL:AF073524 xref: EMBL:AF074717 xref: EMBL:AF076841 xref: EMBL:AF084512 xref: EMBL:AF084513 xref: EMBL:AF090170 xref: EMBL:AJ004974 xref: EMBL:AJ004975 xref: EMBL:BC006837 xref: EMBL:BC009804 xref: EMBL:BC037857 xref: EMBL:BT006908 xref: HGNC:HGNC:9806 xref: UniGene:Hs.531879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001413 ! RAD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005414 name: RAD21_human def: "Double-strand-break repair protein rad21 homolog gene" [UniProtKB:O60216] synonym: "HR21" EXACT [UniProtKB:O60216] synonym: "KIAA0078" EXACT [UniProtKB:O60216] synonym: "NXP1" EXACT [UniProtKB:O60216] xref: EMBL:AY675320 xref: EMBL:BC050381 xref: EMBL:D38551 xref: EMBL:X98294 xref: HGNC:HGNC:9811 xref: UniGene:Hs.81848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001403 ! RAD21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005415 name: RAD50_human def: "DNA repair protein RAD50 gene" [UniProtKB:Q92878] xref: EMBL:AF057299 xref: EMBL:AF057300 xref: EMBL:BC062603 xref: EMBL:BC073850 xref: EMBL:U63139 xref: EMBL:Z75311 xref: HGNC:HGNC:9816 xref: UniGene:Hs.655835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002021 ! RAD50_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005416 name: RAD51_human def: "DNA repair protein RAD51 homolog 1 gene" [UniProtKB:Q06609] synonym: "RAD51A" EXACT [UniProtKB:Q06609] synonym: "RECA" EXACT [UniProtKB:Q06609] xref: EMBL:AF165088 xref: EMBL:AF165089 xref: EMBL:AF165090 xref: EMBL:AF165091 xref: EMBL:AF165092 xref: EMBL:AF165093 xref: EMBL:AF165094 xref: EMBL:AF233740 xref: EMBL:AF233741 xref: EMBL:AF233742 xref: EMBL:AF233743 xref: EMBL:AF233744 xref: EMBL:AF236021 xref: EMBL:AK131299 xref: EMBL:AK291969 xref: EMBL:AY196785 xref: EMBL:BC001459 xref: EMBL:CH471125 xref: EMBL:CR536559 xref: EMBL:D13804 xref: EMBL:D14134 xref: HGNC:HGNC:9817 xref: UniGene:Hs.631709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001721 ! RAD51_HUMAN relationship: codes_for CCO:B0001923 ! Q6ZNA8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005417 name: RAD52_human def: "DNA repair protein RAD52 homolog gene" [UniProtKB:P43351] xref: EMBL:AY527412 xref: EMBL:L33262 xref: EMBL:U12134 xref: EMBL:U27516 xref: HGNC:HGNC:9824 xref: UniGene:Hs.410355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001621 ! RAD52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005418 name: RAD54L_human def: "DNA repair and recombination protein RAD54-like gene" [UniProtKB:Q92698] synonym: "RAD54A" EXACT [UniProtKB:Q92698] xref: EMBL:AL121602 xref: EMBL:AY623117 xref: EMBL:BC121059 xref: EMBL:BC121060 xref: EMBL:X97795 xref: HGNC:HGNC:9826 xref: UniGene:Hs.701999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002016 ! RAD54_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005419 name: RAD9A_human def: "Cell cycle checkpoint control protein RAD9A gene" [UniProtKB:Q99638] xref: EMBL:AY766122 xref: EMBL:BC014848 xref: EMBL:CR536508 xref: EMBL:U53174 xref: HGNC:HGNC:9827 xref: UniGene:Hs.655354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002077 ! RAD9A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005420 name: RAD9B_human def: "Cell cycle checkpoint control protein RAD9B homolog gene" [UniProtKB:Q6WBX8] xref: EMBL:AK058176 xref: EMBL:AK097665 xref: EMBL:AK124109 xref: EMBL:AY297459 xref: EMBL:BC047645 xref: EMBL:BC068031 xref: HGNC:HGNC:21700 xref: UniGene:Hs.97794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001919 ! RAD9B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005421 name: RAF1_human def: "RAF proto-oncogene serine/threonine-protein kinase gene" [UniProtKB:P04049] synonym: "RAF" EXACT [UniProtKB:P04049] xref: EMBL:AY271661 xref: EMBL:BC018119 xref: EMBL:CH471055 xref: EMBL:EU332868 xref: EMBL:L00206 xref: EMBL:L00207 xref: EMBL:L00208 xref: EMBL:L00209 xref: EMBL:L00210 xref: EMBL:L00211 xref: EMBL:L00212 xref: EMBL:L00213 xref: EMBL:M11376 xref: EMBL:X03484 xref: EMBL:X54851 xref: HGNC:HGNC:9829 xref: UniGene:Hs.159130 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005636 ! RAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005422 name: RAI1_human def: "Retinoic acid-induced protein 1 gene" [UniProtKB:Q7Z5J4] synonym: "KIAA1820" EXACT [UniProtKB:Q7Z5J4] xref: EMBL:AB058723 xref: EMBL:AJ271790 xref: EMBL:AJ271791 xref: EMBL:AL133649 xref: EMBL:AL834468 xref: EMBL:AL834486 xref: EMBL:AY172136 xref: EMBL:BC021209 xref: HGNC:HGNC:9834 xref: UniGene:Hs.655395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005192 ! RAI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005423 name: RANBP3_human def: "Ran-binding protein 3 gene" [UniProtKB:Q9H6Z4] xref: EMBL:AC004602 xref: EMBL:AC005784 xref: EMBL:AC093050 xref: EMBL:AC104532 xref: EMBL:AK025300 xref: EMBL:AL050149 xref: EMBL:BC004349 xref: EMBL:Y08697 xref: EMBL:Y08698 xref: HGNC:HGNC:9850 xref: UniGene:Hs.531752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005866 ! RANB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005424 name: RANBP1_human def: "Ran-specific GTPase-activating protein gene" [UniProtKB:P43487] xref: EMBL:CR456556 xref: EMBL:D38076 xref: EMBL:X83617 xref: HGNC:HGNC:9847 xref: UniGene:Hs.24763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005653 ! RANG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005425 name: RAN_human def: "GTP-binding nuclear protein Ran gene" [UniProtKB:P62826] synonym: "ARA24" EXACT [UniProtKB:P62826] synonym: "OK/SW-cl.81" EXACT [UniProtKB:P62826] xref: EMBL:AB062399 xref: EMBL:AF052578 xref: EMBL:AF054183 xref: EMBL:AF501887 xref: EMBL:BC004272 xref: EMBL:BC014518 xref: EMBL:BC014901 xref: EMBL:BC016654 xref: EMBL:BC051908 xref: EMBL:BC072000 xref: EMBL:BT007271 xref: EMBL:CR450347 xref: EMBL:M31469 xref: HGNC:HGNC:9846 xref: UniGene:Hs.10842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001693 ! RAN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005426 name: RAP1A_human def: "Ras-related protein Rap-1A precursor gene" [UniProtKB:P62834] synonym: "KREV1" EXACT [UniProtKB:P62834] xref: EMBL:AF493912 xref: EMBL:AL049557 xref: EMBL:BC014086 xref: EMBL:M22995 xref: EMBL:X12533 xref: HGNC:HGNC:9855 xref: UniGene:Hs.190334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001694 ! RAP1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005427 name: RARA_human def: "Retinoic acid receptor alpha gene" [UniProtKB:P10276] synonym: "NR1B1" EXACT [UniProtKB:P10276] xref: EMBL:AB067754 xref: EMBL:AC080112 xref: EMBL:AF088889 xref: EMBL:AF088890 xref: EMBL:AF088891 xref: EMBL:AF088892 xref: EMBL:AF088893 xref: EMBL:AF088894 xref: EMBL:AF088895 xref: EMBL:AF283809 xref: EMBL:BC008727 xref: EMBL:BC071733 xref: EMBL:CH471152 xref: EMBL:U41742 xref: EMBL:U41743 xref: EMBL:X06538 xref: EMBL:X06614 xref: EMBL:X56058 xref: EMBL:X58685 xref: HGNC:HGNC:9864 xref: UniGene:Hs.654583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024853 ! RARA_HUMAN relationship: codes_for CCO:B0026863 ! A8MUP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005428 name: RASA1_human def: "Ras GTPase-activating protein 1 gene" [UniProtKB:P20936] synonym: "RASA" EXACT [UniProtKB:P20936] xref: EMBL:BC033015 xref: EMBL:M23379 xref: EMBL:M23612 xref: HGNC:HGNC:9871 xref: UniGene:Hs.695926 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005995 ! RASA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005429 name: RASSF1_human def: "Ras association domain-containing protein 1 gene" [UniProtKB:Q9NS23] synonym: "RDA32" EXACT [UniProtKB:Q9NS23] xref: EMBL:AC002455 xref: EMBL:AC002481 xref: EMBL:AF040703 xref: EMBL:AF061836 xref: EMBL:AF102770 xref: EMBL:AF102771 xref: EMBL:AF102772 xref: EMBL:AF132675 xref: EMBL:AF132676 xref: EMBL:AF132677 xref: EMBL:AF286217 xref: EMBL:AF291719 xref: HGNC:HGNC:9882 xref: UniGene:Hs.476270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002162 ! RASF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005430 name: RASSF2_human def: "Ras association domain-containing protein 2 gene" [UniProtKB:P50749] synonym: "KIAA0168" EXACT [UniProtKB:P50749] xref: EMBL:AK222650 xref: EMBL:AK291458 xref: EMBL:AL133354 xref: EMBL:AY154470 xref: EMBL:AY154471 xref: EMBL:AY154472 xref: EMBL:BC110385 xref: EMBL:BC117118 xref: EMBL:BC117120 xref: EMBL:CH471133 xref: EMBL:CR627436 xref: EMBL:D79990 xref: HGNC:HGNC:9883 xref: UniGene:Hs.631504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001646 ! RASF2_HUMAN relationship: codes_for CCO:B0019359 ! Q8IZA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005431 name: RASSF4_human def: "Ras association domain-containing protein 4 gene" [UniProtKB:Q9H2L5] synonym: "AD037" EXACT [UniProtKB:Q9H2L5] xref: EMBL:AF260335 xref: EMBL:AL353801 xref: EMBL:AL713716 xref: EMBL:AY216713 xref: EMBL:AY216714 xref: EMBL:AY216715 xref: EMBL:AY216716 xref: EMBL:BC032593 xref: HGNC:HGNC:20793 xref: UniGene:Hs.522895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002129 ! RASF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005432 name: RASSF5_human def: "Ras association domain-containing protein 5 gene" [UniProtKB:Q8WWW0] synonym: "NORE1" EXACT [UniProtKB:Q8WWW0] synonym: "RAPL" EXACT [UniProtKB:Q8WWW0] xref: EMBL:AF445801 xref: EMBL:AL354681 xref: EMBL:AL591846 xref: EMBL:AL832784 xref: EMBL:AY062002 xref: EMBL:AY062003 xref: EMBL:AY216268 xref: EMBL:AY261332 xref: EMBL:BC004270 xref: EMBL:BC007203 xref: EMBL:BC042651 xref: HGNC:HGNC:17609 xref: UniGene:Hs.497579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002008 ! RASF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005433 name: HRAS_human def: "GTPase HRas precursor gene" [UniProtKB:P01112] synonym: "HRAS1" EXACT [UniProtKB:P01112] xref: EMBL:AB451336 xref: EMBL:AB451485 xref: EMBL:AF493916 xref: EMBL:AJ437024 xref: EMBL:BC006499 xref: EMBL:BC095471 xref: EMBL:BT019421 xref: EMBL:CH471158 xref: EMBL:CR536579 xref: EMBL:CR542271 xref: EMBL:EF015887 xref: EMBL:J00277 xref: EMBL:M17232 xref: HGNC:HGNC:5173 xref: UniGene:Hs.37003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001467 ! RASH_HUMAN relationship: codes_for CCO:B0016257 ! Q9BR65_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005434 name: KRAS_human def: "GTPase KRas precursor gene" [UniProtKB:P01116] synonym: "KRAS2" EXACT [UniProtKB:P01116] synonym: "RASK2" EXACT [UniProtKB:P01116] xref: EMBL:AF285779 xref: EMBL:AF493917 xref: EMBL:BC013572 xref: EMBL:BT007153 xref: EMBL:EF685661 xref: EMBL:EF685662 xref: EMBL:K01519 xref: EMBL:K01520 xref: EMBL:K03209 xref: EMBL:K03210 xref: EMBL:L00045 xref: EMBL:L00046 xref: EMBL:L00047 xref: EMBL:L00048 xref: EMBL:L00049 xref: EMBL:M25876 xref: EMBL:M30539 xref: EMBL:M34904 xref: EMBL:M54968 xref: EMBL:X01669 xref: EMBL:X02825 xref: HGNC:HGNC:6407 xref: UniGene:Hs.37003 xref: UniGene:Hs.505033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001468 ! RASK_HUMAN relationship: codes_for CCO:B0057097 ! Q71SP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005435 name: NRAS_human def: "GTPase NRas precursor gene" [UniProtKB:P01111] synonym: "HRAS1" EXACT [UniProtKB:P01111] xref: EMBL:AF493919 xref: EMBL:AY428630 xref: EMBL:BC005219 xref: EMBL:K03211 xref: EMBL:L00040 xref: EMBL:L00041 xref: EMBL:L00042 xref: EMBL:L00043 xref: EMBL:M10055 xref: EMBL:M25898 xref: EMBL:X00642 xref: EMBL:X00643 xref: EMBL:X00644 xref: EMBL:X00645 xref: EMBL:X02751 xref: EMBL:X05565 xref: EMBL:X07440 xref: EMBL:X53291 xref: EMBL:X53292 xref: HGNC:HGNC:7989 xref: UniGene:Hs.37003 xref: UniGene:Hs.486502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001466 ! RASN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005436 name: RAB22A_human def: "Ras-related protein Rab-22A gene" [UniProtKB:Q9UL26] synonym: "RAB22" EXACT [UniProtKB:Q9UL26] xref: EMBL:AF091034 xref: EMBL:AF125104 xref: EMBL:AJ276210 xref: EMBL:AL035455 xref: EMBL:BC015710 xref: EMBL:BC063457 xref: EMBL:BT007046 xref: HGNC:HGNC:9764 xref: UniGene:Hs.529044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005237 ! RB22A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005437 name: RAB27A_human def: "Ras-related protein Rab-27A gene" [UniProtKB:P51159] synonym: "RAB27" EXACT [UniProtKB:P51159] xref: EMBL:AF125393 xref: EMBL:AF154836 xref: EMBL:AF154837 xref: EMBL:AF154838 xref: EMBL:AF154839 xref: EMBL:AF154840 xref: EMBL:AF443871 xref: EMBL:AF498953 xref: EMBL:BC107680 xref: EMBL:CR536496 xref: EMBL:CR541693 xref: EMBL:U38654 xref: EMBL:U57094 xref: HGNC:HGNC:9766 xref: UniGene:Hs.654978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006223 ! RB27A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005438 name: RBBP4_human def: "Histone-binding protein RBBP4 gene" [UniProtKB:Q09028] synonym: "RBAP48" EXACT [UniProtKB:Q09028] xref: EMBL:AK222779 xref: EMBL:BC003092 xref: EMBL:BC015123 xref: EMBL:BC053904 xref: EMBL:BC075836 xref: EMBL:BT007309 xref: EMBL:X71810 xref: EMBL:X74262 xref: HGNC:HGNC:9887 xref: UniGene:Hs.647652 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001727 ! RBBP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005439 name: RBBP5_human def: "Retinoblastoma-binding protein 5 gene" [UniProtKB:Q15291] synonym: "RBQ3" EXACT [UniProtKB:Q15291] xref: EMBL:AC093422 xref: EMBL:AK290137 xref: EMBL:AL583832 xref: EMBL:BC037284 xref: EMBL:BC053856 xref: EMBL:BC075059 xref: EMBL:BC075060 xref: EMBL:CH471067 xref: EMBL:X85134 xref: HGNC:HGNC:9888 xref: UniGene:Hs.519230 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005660 ! RBBP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005441 name: RBBP7_human def: "Histone-binding protein RBBP7 gene" [UniProtKB:Q16576] synonym: "RBAP46" EXACT [UniProtKB:Q16576] xref: EMBL:U35143 xref: EMBL:X72841 xref: HGNC:HGNC:9890 xref: UniGene:Hs.495755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005809 ! RBBP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005442 name: RBBP8_human def: "Retinoblastoma-binding protein 8 gene" [UniProtKB:Q99708] synonym: "CTIP" EXACT [UniProtKB:Q99708] xref: EMBL:AF043431 xref: EMBL:BC030590 xref: EMBL:U72066 xref: HGNC:HGNC:9891 xref: UniGene:Hs.546282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002084 ! RBBP8_HUMAN relationship: codes_for CCO:B0005289 ! Q8NHQ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005443 name: RB1CC1_human def: "RB1-inducible coiled-coil protein 1 gene" [UniProtKB:Q8TDY2] synonym: "KIAA0203" EXACT [UniProtKB:Q8TDY2] synonym: "RBICC" EXACT [UniProtKB:Q8TDY2] xref: EMBL:AB059622 xref: EMBL:AC090814 xref: EMBL:AC113139 xref: EMBL:BC017556 xref: EMBL:D86958 xref: HGNC:HGNC:15574 xref: UniGene:Hs.196102 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001995 ! RBCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005444 name: RABGAP1_human def: "Rab GTPase-activating protein 1 gene" [UniProtKB:Q9Y3P9] synonym: "HSPC094" EXACT [UniProtKB:Q9Y3P9] xref: EMBL:AC007066 xref: EMBL:AF161357 xref: EMBL:AJ011679 xref: EMBL:AK022408 xref: EMBL:AK131449 xref: EMBL:AL050195 xref: EMBL:AL365338 xref: EMBL:BC020609 xref: EMBL:BC054492 xref: HGNC:HGNC:17155 xref: UniGene:Hs.271341 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002254 ! RBGP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005445 name: RBL1_human def: "Retinoblastoma-like protein 1 gene" [UniProtKB:P28749] xref: EMBL:AL136172 xref: EMBL:AL365505 xref: EMBL:AL391114 xref: EMBL:BC032247 xref: EMBL:L14812 xref: EMBL:M74547 xref: EMBL:S78664 xref: HGNC:HGNC:9893 xref: UniGene:Hs.207745 xref: UniGene:Hs.617220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001567 ! RBL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005446 name: RBL2_human def: "Retinoblastoma-like protein 2 gene" [UniProtKB:Q08999] synonym: "RB2" EXACT [UniProtKB:Q08999] xref: EMBL:S67171 xref: EMBL:U53220 xref: EMBL:X74594 xref: EMBL:X76061 xref: HGNC:HGNC:9894 xref: UniGene:Hs.513609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001725 ! RBL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005448 name: RBM5_human def: "RNA-binding protein 5 gene" [UniProtKB:P52756] synonym: "H37" EXACT [UniProtKB:P52756] synonym: "LUCA15" EXACT [UniProtKB:P52756] xref: EMBL:AF091263 xref: EMBL:AF103802 xref: EMBL:U23946 xref: EMBL:U73168 xref: HGNC:HGNC:9902 xref: UniGene:Hs.439480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001660 ! RBM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005449 name: RBM7_human def: "RNA-binding protein 7 gene" [UniProtKB:Q9Y580] xref: EMBL:AF156098 xref: EMBL:AK002015 xref: EMBL:BC034381 xref: HGNC:HGNC:9904 xref: UniGene:Hs.533736 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002255 ! RBM7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005450 name: RBM8A_human def: "RNA-binding protein 8A gene" [UniProtKB:Q9Y5S9] synonym: "HSPC114" EXACT [UniProtKB:Q9Y5S9] synonym: "MDS014" EXACT [UniProtKB:Q9Y5S9] synonym: "RBM8" EXACT [UniProtKB:Q9Y5S9] xref: EMBL:AF127761 xref: EMBL:AF161463 xref: EMBL:AF182415 xref: EMBL:AF198620 xref: EMBL:AF231511 xref: EMBL:AF231512 xref: EMBL:AF299118 xref: EMBL:AF403012 xref: EMBL:BC017088 xref: EMBL:BC071577 xref: EMBL:CR541805 xref: EMBL:CR541823 xref: HGNC:HGNC:9905 xref: UniGene:Hs.654719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005223 ! RBM8A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005451 name: RBPMS_human def: "RNA-binding protein with multiple splicing gene" [UniProtKB:Q93062] xref: EMBL:BC003608 xref: EMBL:D84107 xref: EMBL:D84108 xref: EMBL:D84109 xref: EMBL:D84110 xref: EMBL:D84111 xref: HGNC:HGNC:19097 xref: UniGene:Hs.334587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005178 ! RBPMS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005452 name: LMO2_human def: "Rhombotin-2 gene" [UniProtKB:P25791] synonym: "RBTN2" EXACT [UniProtKB:P25791] synonym: "RBTNL1" EXACT [UniProtKB:P25791] synonym: "RHOM2" EXACT [UniProtKB:P25791] synonym: "TTG2" EXACT [UniProtKB:P25791] xref: EMBL:AF257211 xref: EMBL:BC034041 xref: EMBL:BC035607 xref: EMBL:BC042426 xref: EMBL:BC073973 xref: EMBL:X61118 xref: HGNC:HGNC:6642 xref: UniGene:Hs.34560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005171 ! RBTN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005453 name: RBX1_human def: "RING-box protein 1 gene" [UniProtKB:P62877] synonym: "RNF75" EXACT [UniProtKB:P62877] synonym: "ROC1" EXACT [UniProtKB:P62877] xref: EMBL:AF140598 xref: EMBL:AF142059 xref: EMBL:AL080242 xref: EMBL:AY099360 xref: EMBL:BC001466 xref: EMBL:BC017370 xref: EMBL:CR456560 xref: HGNC:HGNC:9928 xref: UniGene:Hs.474949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005491 ! RBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005454 name: RB1_human def: "Retinoblastoma-associated protein gene" [UniProtKB:P06400] xref: EMBL:AF551763 xref: EMBL:AL136960 xref: EMBL:AL392048 xref: EMBL:BC039060 xref: EMBL:BC040540 xref: EMBL:L11910 xref: EMBL:L35146 xref: EMBL:L35147 xref: EMBL:L41870 xref: EMBL:L41889 xref: EMBL:L41890 xref: EMBL:L41891 xref: EMBL:L41893 xref: EMBL:L41894 xref: EMBL:L41895 xref: EMBL:L41896 xref: EMBL:L41897 xref: EMBL:L41898 xref: EMBL:L41899 xref: EMBL:L41997 xref: EMBL:M15400 xref: EMBL:M19701 xref: EMBL:M27845 xref: EMBL:M27846 xref: EMBL:M27847 xref: EMBL:M27849 xref: EMBL:M27850 xref: EMBL:M27851 xref: EMBL:M27852 xref: EMBL:M27853 xref: EMBL:M27854 xref: EMBL:M27855 xref: EMBL:M27856 xref: EMBL:M27857 xref: EMBL:M27858 xref: EMBL:M27859 xref: EMBL:M27860 xref: EMBL:M27862 xref: EMBL:M27863 xref: EMBL:M27864 xref: EMBL:M27865 xref: EMBL:M27866 xref: EMBL:M28419 xref: EMBL:M33647 xref: EMBL:X16439 xref: HGNC:HGNC:9884 xref: UniGene:Hs.408528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001491 ! RB_HUMAN relationship: codes_for CCO:B0058083 ! Q92728_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005455 name: RCBTB1_human def: "RCC1 and BTB domain-containing protein 1 gene" [UniProtKB:Q8NDN9] synonym: "CLLD7" EXACT [UniProtKB:Q8NDN9] synonym: "E4.5" EXACT [UniProtKB:Q8NDN9] xref: EMBL:AF334406 xref: EMBL:AJ319660 xref: EMBL:AK096654 xref: EMBL:AL139321 xref: EMBL:AL833821 xref: HGNC:HGNC:18243 xref: UniGene:Hs.508021 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001976 ! RCBT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005456 name: RCC1_human def: "Regulator of chromosome condensation gene" [UniProtKB:P18754] synonym: "CHC1" EXACT [UniProtKB:P18754] xref: EMBL:AF498924 xref: EMBL:BC007300 xref: EMBL:BC010067 xref: EMBL:BC036903 xref: EMBL:D00591 xref: EMBL:X06130 xref: EMBL:X12654 xref: HGNC:HGNC:1913 xref: UniGene:Hs.469723 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001533 ! RCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005457 name: RCC2_human def: "Protein RCC2 gene" [UniProtKB:Q9P258] synonym: "KIAA1470" EXACT [UniProtKB:Q9P258] synonym: "TD60" EXACT [UniProtKB:Q9P258] xref: EMBL:AB040903 xref: EMBL:AJ421269 xref: EMBL:AL359612 xref: EMBL:BC004933 xref: EMBL:BC042141 xref: EMBL:BC053908 xref: HGNC:HGNC:30297 xref: UniGene:Hs.380857 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002186 ! RCC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005458 name: RCN3_human def: "Reticulocalbin-3 precursor gene" [UniProtKB:Q96D15] synonym: "UNQ239/PRO272" EXACT [UniProtKB:Q96D15] xref: EMBL:AF183423 xref: EMBL:AY195859 xref: EMBL:AY358423 xref: EMBL:BC013436 xref: HGNC:HGNC:21145 xref: UniGene:Hs.567550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005248 ! RCN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005459 name: REC8_human def: "Meiotic recombination protein REC8 homolog gene" [UniProtKB:O95072] synonym: "REC8L1" EXACT [UniProtKB:O95072] xref: EMBL:AF006264 xref: EMBL:AK001435 xref: EMBL:BC004159 xref: EMBL:BC010887 xref: EMBL:BC019326 xref: EMBL:CR457263 xref: HGNC:HGNC:16879 xref: UniGene:Hs.419259 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001447 ! REC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005460 name: RECK_human def: "Reversion-inducing cysteine-rich protein with Kazal motifs precursor gene" [UniProtKB:O95980] synonym: "ST15" EXACT [UniProtKB:O95980] xref: EMBL:AL138834 xref: EMBL:AL158830 xref: EMBL:D50406 xref: HGNC:HGNC:11345 xref: UniGene:Hs.388918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001455 ! RECK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005461 name: RECQL4_human def: "ATP-dependent DNA helicase Q4 gene" [UniProtKB:O94761] synonym: "RECQ4" EXACT [UniProtKB:O94761] xref: EMBL:AB006532 xref: EMBL:AB026546 xref: EMBL:BC011602 xref: EMBL:BC013277 xref: EMBL:DQ176868 xref: HGNC:HGNC:9949 xref: UniGene:Hs.31442 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001442 ! RECQ4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005462 name: RECQL5_human def: "ATP-dependent DNA helicase Q5 gene" [UniProtKB:O94762] synonym: "RECQ5" EXACT [UniProtKB:O94762] xref: EMBL:AB006533 xref: EMBL:AB042823 xref: EMBL:AB042824 xref: EMBL:AB042825 xref: EMBL:AF135183 xref: EMBL:BC016911 xref: HGNC:HGNC:9950 xref: UniGene:Hs.632229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006224 ! RECQ5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005463 name: IK_human def: "Protein Red gene" [UniProtKB:Q13123] synonym: "RED" EXACT [UniProtKB:Q13123] synonym: "RER" EXACT [UniProtKB:Q13123] xref: EMBL:AJ005579 xref: EMBL:S74221 xref: HGNC:HGNC:5958 xref: UniGene:Hs.421245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006239 ! RED_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005464 name: RELB_human def: "Transcription factor RelB gene" [UniProtKB:Q01201] xref: EMBL:AF043454 xref: EMBL:AF043455 xref: EMBL:AF043456 xref: EMBL:AF043457 xref: EMBL:AF043458 xref: EMBL:AF043459 xref: EMBL:AF043460 xref: EMBL:AF043461 xref: EMBL:AF043462 xref: EMBL:AF043463 xref: EMBL:BC028013 xref: EMBL:DQ314887 xref: EMBL:M83221 xref: HGNC:HGNC:9956 xref: UniGene:Hs.654402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005529 ! RELB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005465 name: UPF3A_human def: "Regulator of nonsense transcripts 3A gene" [UniProtKB:Q9H1J1] synonym: "RENT3A" EXACT [UniProtKB:Q9H1J1] synonym: "UPF3" EXACT [UniProtKB:Q9H1J1] xref: EMBL:AF318575 xref: EMBL:AL160396 xref: EMBL:AY013250 xref: EMBL:BC008694 xref: EMBL:BC023569 xref: HGNC:HGNC:20332 xref: UniGene:Hs.533855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005436 ! REN3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005466 name: UPF3B_human def: "Regulator of nonsense transcripts 3B gene" [UniProtKB:Q9BZI7] synonym: "RENT3B" EXACT [UniProtKB:Q9BZI7] synonym: "UPF3X" EXACT [UniProtKB:Q9BZI7] xref: EMBL:AF318576 xref: EMBL:AY013251 xref: EMBL:BC121017 xref: HGNC:HGNC:20439 xref: UniGene:Hs.103832 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005434 ! REN3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005467 name: UPF1_human def: "Regulator of nonsense transcripts 1 gene" [UniProtKB:Q92900] synonym: "KIAA0221" EXACT [UniProtKB:Q92900] synonym: "RENT1" EXACT [UniProtKB:Q92900] xref: EMBL:AC003972 xref: EMBL:AF074016 xref: EMBL:BC039817 xref: EMBL:D86988 xref: EMBL:U59323 xref: EMBL:U65533 xref: HGNC:HGNC:9962 xref: UniGene:Hs.515266 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002024 ! RENT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005468 name: UPF2_human def: "Regulator of nonsense transcripts 2 gene" [UniProtKB:Q9HAU5] synonym: "KIAA1408" EXACT [UniProtKB:Q9HAU5] synonym: "RENT2" EXACT [UniProtKB:Q9HAU5] xref: EMBL:AB037829 xref: EMBL:AC073160 xref: EMBL:AF301013 xref: EMBL:AF318574 xref: EMBL:AK000764 xref: EMBL:AK096191 xref: EMBL:AL080198 xref: EMBL:AL138898 xref: EMBL:AL645617 xref: EMBL:AY013249 xref: EMBL:BC114964 xref: EMBL:BC115737 xref: HGNC:HGNC:17854 xref: UniGene:Hs.370689 xref: UniGene:Hs.610110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005435 ! RENT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005469 name: RPA1_human def: "Replication protein A 70 kDa DNA-binding subunit gene" [UniProtKB:P27694] synonym: "REPA1" EXACT [UniProtKB:P27694] synonym: "RPA70" EXACT [UniProtKB:P27694] xref: EMBL:AB209732 xref: EMBL:AY599563 xref: EMBL:BC018126 xref: EMBL:M63488 xref: HGNC:HGNC:10289 xref: UniGene:Hs.461925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001562 ! RFA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005470 name: RPA2_human def: "Replication protein A 32 kDa subunit gene" [UniProtKB:P15927] synonym: "REPA2" EXACT [UniProtKB:P15927] synonym: "RPA32" EXACT [UniProtKB:P15927] synonym: "RPA34" EXACT [UniProtKB:P15927] xref: EMBL:AL109927 xref: EMBL:BC001630 xref: EMBL:BC012157 xref: EMBL:BC021257 xref: EMBL:CR450348 xref: EMBL:DQ001128 xref: EMBL:J05249 xref: HGNC:HGNC:10290 xref: UniGene:Hs.79411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005500 ! RFA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005471 name: RPA3_human def: "Replication protein A 14 kDa subunit gene" [UniProtKB:P35244] synonym: "REPA3" EXACT [UniProtKB:P35244] synonym: "RPA14" EXACT [UniProtKB:P35244] xref: EMBL:AC004948 xref: EMBL:BC005264 xref: EMBL:BC009868 xref: EMBL:BT007320 xref: EMBL:DQ003136 xref: EMBL:L07493 xref: HGNC:HGNC:10291 xref: UniGene:Hs.487540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005501 ! RFA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005472 name: RFC1_human def: "Replication factor C subunit 1 gene" [UniProtKB:P35251] synonym: "RFC140" EXACT [UniProtKB:P35251] xref: EMBL:AF040250 xref: EMBL:AY600371 xref: EMBL:BC035297 xref: EMBL:BC051751 xref: EMBL:BC051786 xref: EMBL:L23320 xref: EMBL:Z22642 xref: HGNC:HGNC:9969 xref: UniGene:Hs.507475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005887 ! RFC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005473 name: RFC5_human def: "Replication factor C subunit 5 gene" [UniProtKB:P40937] xref: EMBL:AY254323 xref: EMBL:BC001866 xref: EMBL:BC013961 xref: EMBL:CR407651 xref: EMBL:L07540 xref: HGNC:HGNC:9973 xref: UniGene:Hs.506989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006105 ! RFC5_HUMAN relationship: codes_for CCO:B0017050 ! Q6LES9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005474 name: RAB11FIP4_human def: "Rab11 family-interacting protein 4 gene" [UniProtKB:Q86YS3] synonym: "KIAA1821" EXACT [UniProtKB:Q86YS3] xref: EMBL:AB058724 xref: EMBL:AJ314646 xref: EMBL:AK097424 xref: EMBL:AL831830 xref: EMBL:AY169244 xref: EMBL:BC093914 xref: EMBL:BC101517 xref: HGNC:HGNC:30267 xref: UniGene:Hs.406788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005979 ! RFIP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005475 name: RFWD2_human def: "E3 ubiquitin-protein ligase RFWD2 gene" [UniProtKB:Q8NHY2] synonym: "COP1" EXACT [UniProtKB:Q8NHY2] synonym: "RNF200" EXACT [UniProtKB:Q8NHY2] xref: EMBL:AF508940 xref: EMBL:AK025789 xref: EMBL:AY509921 xref: EMBL:BK000438 xref: HGNC:HGNC:17440 xref: UniGene:Hs.523744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006001 ! RFWD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005476 name: RFX1_human def: "MHC class II regulatory factor RFX1 gene" [UniProtKB:P22670] xref: EMBL:BC049826 xref: EMBL:X58964 xref: HGNC:HGNC:9982 xref: UniGene:Hs.655215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006243 ! RFX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005477 name: RACGAP1_human def: "Rac GTPase-activating protein 1 gene" [UniProtKB:Q9H0H5] synonym: "KIAA1478" EXACT [UniProtKB:Q9H0H5] synonym: "MGCRACGAP" EXACT [UniProtKB:Q9H0H5] xref: EMBL:AB030251 xref: EMBL:AB040911 xref: EMBL:AK000733 xref: EMBL:AL136794 xref: EMBL:BC024144 xref: EMBL:BC032754 xref: EMBL:CR533565 xref: HGNC:HGNC:9804 xref: UniGene:Hs.505469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002124 ! RGAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005478 name: RGC32_human def: "Response gene to complement 32 protein gene" [UniProtKB:Q9H4X1] synonym: "C13orf15" EXACT [UniProtKB:Q9H4X1] xref: EMBL:AF036549 xref: EMBL:AL354833 xref: EMBL:BC066334 xref: HGNC:HGNC:20369 xref: UniGene:Hs.507866 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002137 ! RGC32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005479 name: RGL1_human def: "Ral guanine nucleotide dissociation stimulator-like 1 gene" [UniProtKB:Q9NZL6] synonym: "KIAA0959" EXACT [UniProtKB:Q9NZL6] synonym: "RGL" EXACT [UniProtKB:Q9NZL6] xref: EMBL:AB023176 xref: EMBL:AF186779 xref: EMBL:AF186780 xref: EMBL:AF186781 xref: EMBL:AF186783 xref: EMBL:AF186784 xref: EMBL:AF186785 xref: EMBL:AF186786 xref: EMBL:AF186787 xref: EMBL:AF186788 xref: EMBL:AF186789 xref: EMBL:AF186790 xref: EMBL:AF186791 xref: EMBL:AF186792 xref: EMBL:AF186793 xref: EMBL:AF186794 xref: EMBL:AF186795 xref: EMBL:AF186796 xref: EMBL:AF186797 xref: EMBL:AF186798 xref: EMBL:AF192520 xref: EMBL:AL080117 xref: HGNC:HGNC:30281 xref: UniGene:Hs.497148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005550 ! RGL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005480 name: RGS2_human def: "Regulator of G-protein signaling 2 gene" [UniProtKB:P41220] synonym: "G0S8" EXACT [UniProtKB:P41220] synonym: "GIG31" EXACT [UniProtKB:P41220] xref: EMBL:AF493926 xref: EMBL:AK313668 xref: EMBL:AL035407 xref: EMBL:AY971351 xref: EMBL:BC007049 xref: EMBL:BT007065 xref: EMBL:CH471067 xref: EMBL:CR457410 xref: EMBL:L13391 xref: EMBL:L13463 xref: HGNC:HGNC:9998 xref: UniGene:Hs.78944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001605 ! RGS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005481 name: ARHGAP8_human def: "Rho GTPase-activating protein 8 gene" [UniProtKB:P85298] xref: EMBL:AK001306 xref: EMBL:AK022305 xref: EMBL:BC048280 xref: EMBL:BC059382 xref: EMBL:Z83838 xref: EMBL:Z93244 xref: EMBL:Z98743 xref: HGNC:HGNC:677 xref: UniGene:Hs.102336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041474 ! B1AHC4_HUMAN relationship: codes_for CCO:B0053943 ! A6ZJ79_HUMAN relationship: codes_for CCO:B0054210 ! B1AHB8_HUMAN relationship: codes_for CCO:B0054211 ! B1AHC3_HUMAN relationship: codes_for CCO:B0055664 ! RHG08_HUMAN relationship: codes_for CCO:B0056899 ! Q6PCC7_HUMAN relationship: codes_for CCO:B0057297 ! Q86XV6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005482 name: ARHGAP18_human def: "Rho GTPase-activating protein 18 gene" [UniProtKB:Q8N392] xref: EMBL:AB053293 xref: EMBL:AL450310 xref: EMBL:AL834511 xref: EMBL:BC017223 xref: EMBL:BC039611 xref: EMBL:BC062417 xref: EMBL:BC101708 xref: EMBL:BC107416 xref: EMBL:BC111940 xref: HGNC:HGNC:21035 xref: UniGene:Hs.486458 xref: UniGene:Hs.669689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005564 ! RHG18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005483 name: ARHGAP20_human def: "Rho GTPase-activating protein 20 gene" [UniProtKB:Q9P2F6] synonym: "KIAA1391" EXACT [UniProtKB:Q9P2F6] xref: EMBL:AB037812 xref: EMBL:AY496263 xref: EMBL:AY496264 xref: EMBL:AY496265 xref: EMBL:AY496266 xref: EMBL:AY496267 xref: EMBL:BC039340 xref: HGNC:HGNC:18357 xref: UniGene:Hs.6136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002188 ! RHG20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005484 name: RHOB_human def: "Rho-related GTP-binding protein RhoB precursor gene" [UniProtKB:P62745] synonym: "ARH6" EXACT [UniProtKB:P62745] synonym: "ARHB" EXACT [UniProtKB:P62745] xref: EMBL:AC023137 xref: EMBL:AF498971 xref: EMBL:BC066954 xref: EMBL:BK001232 xref: EMBL:BK001671 xref: EMBL:BT019546 xref: EMBL:BT019547 xref: EMBL:CR542272 xref: EMBL:M12174 xref: EMBL:X06820 xref: HGNC:HGNC:668 xref: UniGene:Hs.502876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001692 ! RHOB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005485 name: RHOG_human def: "Rho-related GTP-binding protein RhoG precursor gene" [UniProtKB:P84095] synonym: "ARHG" EXACT [UniProtKB:P84095] xref: EMBL:AF498974 xref: EMBL:AY563952 xref: EMBL:L11317 xref: EMBL:X61587 xref: HGNC:HGNC:672 xref: UniGene:Hs.501728 xref: UniGene:Hs.705620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001704 ! RHOG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005486 name: RHOXF2_human def: "Rhox homeobox family member 2 gene" [UniProtKB:Q9BQY4] synonym: "PEPP2" EXACT [UniProtKB:Q9BQY4] synonym: "THG1" EXACT [UniProtKB:Q9BQY4] xref: EMBL:AF317219 xref: EMBL:AK058125 xref: EMBL:AL590526 xref: EMBL:BC021719 xref: HGNC:HGNC:30011 xref: UniGene:Hs.196956 xref: UniGene:Hs.567620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005274 ! RHXF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005487 name: RPN1_human def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor gene" [UniProtKB:P04843] xref: EMBL:BC010839 xref: EMBL:CR749284 xref: EMBL:Y00281 xref: HGNC:HGNC:10381 xref: UniGene:Hs.518244 xref: UniGene:Hs.603636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040688 ! RPN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005488 name: RIBC2_human def: "RIB43A-like with coiled-coils protein 2 gene" [UniProtKB:Q9H4K1] synonym: "C22orf11" EXACT [UniProtKB:Q9H4K1] xref: EMBL:AL021391 xref: EMBL:AL050075 xref: EMBL:AL442116 xref: EMBL:BC003024 xref: EMBL:BC009904 xref: EMBL:CR456438 xref: EMBL:CR457398 xref: HGNC:HGNC:13241 xref: UniGene:Hs.475110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005240 ! RIBC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005489 name: RIF1_human def: "Telomere-associated protein RIF1 gene" [UniProtKB:Q5UIP0] xref: EMBL:AC009497 xref: EMBL:AK001461 xref: EMBL:AK022932 xref: EMBL:AK024033 xref: EMBL:AK074349 xref: EMBL:AL080129 xref: EMBL:AY584066 xref: EMBL:AY585745 xref: EMBL:AY727910 xref: EMBL:AY727911 xref: EMBL:AY727912 xref: EMBL:AY727913 xref: EMBL:CR933663 xref: EMBL:U79263 xref: HGNC:HGNC:23207 xref: UniGene:Hs.655671 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001897 ! RIF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005490 name: RIN1_human def: "Ras and Rab interactor 1 gene" [UniProtKB:Q13671] xref: EMBL:BC014417 xref: EMBL:L36463 xref: HGNC:HGNC:18749 xref: UniGene:Hs.1030 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005385 ! RIN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005491 name: RINT1_human def: "RAD50-interacting protein 1 gene" [UniProtKB:Q6NUQ1] xref: EMBL:AC073073 xref: EMBL:AF317622 xref: EMBL:AK021847 xref: EMBL:BC007120 xref: EMBL:BC068483 xref: HGNC:HGNC:21876 xref: UniGene:Hs.592270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001909 ! RINT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005492 name: RIPK1_human def: "Receptor-interacting serine/threonine-protein kinase 1 gene" [UniProtKB:Q13546] synonym: "RIP" EXACT [UniProtKB:Q13546] xref: EMBL:AL031963 xref: EMBL:AY682848 xref: EMBL:BC126254 xref: EMBL:BC126256 xref: EMBL:U25994 xref: EMBL:U50062 xref: HGNC:HGNC:10019 xref: UniGene:Hs.519842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005673 ! RIPK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005493 name: RIPK2_human def: "Receptor-interacting serine/threonine-protein kinase 2 gene" [UniProtKB:O43353] synonym: "CARDIAK" EXACT [UniProtKB:O43353] synonym: "RICK" EXACT [UniProtKB:O43353] synonym: "RIP2" EXACT [UniProtKB:O43353] synonym: "UNQ277/PRO314/PRO34092" EXACT [UniProtKB:O43353] xref: EMBL:AC004003 xref: EMBL:AF027706 xref: EMBL:AF064824 xref: EMBL:AF078530 xref: EMBL:AF117829 xref: EMBL:AY358813 xref: EMBL:AY358814 xref: EMBL:BC004553 xref: HGNC:HGNC:10020 xref: UniGene:Hs.103755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005216 ! RIPK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005494 name: RRM1_human def: "Ribonucleoside-diphosphate reductase large subunit gene" [UniProtKB:P23921] synonym: "RR1" EXACT [UniProtKB:P23921] xref: EMBL:AF107045 xref: EMBL:BC006498 xref: EMBL:L10342 xref: EMBL:X59543 xref: EMBL:X59617 xref: HGNC:HGNC:10451 xref: UniGene:Hs.558393 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006232 ! RIR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005495 name: RIT1_human def: "GTP-binding protein Rit1 gene" [UniProtKB:Q92963] synonym: "RIBB" EXACT [UniProtKB:Q92963] synonym: "RIT" EXACT [UniProtKB:Q92963] synonym: "ROC1" EXACT [UniProtKB:Q92963] xref: EMBL:AF084462 xref: EMBL:AF493923 xref: EMBL:AL139128 xref: EMBL:AL355388 xref: EMBL:U71203 xref: EMBL:U78165 xref: EMBL:Y07566 xref: HGNC:HGNC:10023 xref: UniGene:Hs.491234 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006229 ! RIT1_HUMAN relationship: codes_for CCO:B0056667 ! Q5VY89_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005496 name: RPL11_human def: "60S ribosomal protein L11 gene" [UniProtKB:P62913] xref: EMBL:AB007171 xref: EMBL:AF101385 xref: EMBL:AF432212 xref: EMBL:BC018970 xref: EMBL:L05092 xref: EMBL:X79234 xref: HGNC:HGNC:10301 xref: UniGene:Hs.388664 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005858 ! RL11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005497 name: RPL12_human def: "60S ribosomal protein L12 gene" [UniProtKB:P30050] xref: EMBL:AL445222 xref: EMBL:BC050644 xref: EMBL:BC059950 xref: EMBL:BC094831 xref: EMBL:BC105603 xref: EMBL:CH471090 xref: EMBL:L06505 xref: HGNC:HGNC:10302 xref: UniGene:Hs.408054 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005855 ! RL12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005498 name: RPL15_human def: "60S ribosomal protein L15 gene" [UniProtKB:P61313] synonym: "EC45" EXACT [UniProtKB:P61313] synonym: "TCBAP0781" EXACT [UniProtKB:P61313] xref: EMBL:AB061823 xref: EMBL:AF279903 xref: EMBL:AF283772 xref: EMBL:AY347528 xref: EMBL:BC014837 xref: EMBL:BC068198 xref: EMBL:BC070328 xref: EMBL:BC071672 xref: EMBL:L25899 xref: HGNC:HGNC:10306 xref: UniGene:Hs.381219 xref: UniGene:Hs.695621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005857 ! RL15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005499 name: RPL18A_human def: "60S ribosomal protein L18a gene" [UniProtKB:Q02543] xref: EMBL:AC005796 xref: EMBL:BC007512 xref: EMBL:BC066319 xref: EMBL:BC071920 xref: EMBL:L05093 xref: EMBL:X80822 xref: HGNC:HGNC:10311 xref: UniGene:Hs.337766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006300 ! RL18A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005500 name: RPL18_human def: "60S ribosomal protein L18 gene" [UniProtKB:Q07020] xref: EMBL:AB061825 xref: EMBL:BC000374 xref: EMBL:BC009708 xref: EMBL:BC021743 xref: EMBL:L11566 xref: HGNC:HGNC:10310 xref: UniGene:Hs.515517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005741 ! RL18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005501 name: RPL21_human def: "60S ribosomal protein L21 gene" [UniProtKB:P46778] xref: EMBL:AB007176 xref: EMBL:AB061826 xref: EMBL:BC001603 xref: EMBL:BC007505 xref: EMBL:BC062981 xref: EMBL:BC070184 xref: EMBL:BC070323 xref: EMBL:BC070330 xref: EMBL:L38826 xref: EMBL:U14967 xref: EMBL:U25789 xref: EMBL:X89401 xref: HGNC:HGNC:10313 xref: UniGene:Hs.381123 xref: UniGene:Hs.702965 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005862 ! RL21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005502 name: RPL22_human def: "60S ribosomal protein L22 gene" [UniProtKB:P35268] xref: EMBL:AL031847 xref: EMBL:BC035566 xref: EMBL:BC058887 xref: EMBL:BC066314 xref: EMBL:CH471130 xref: EMBL:CR456873 xref: EMBL:D17652 xref: EMBL:X59357 xref: HGNC:HGNC:10315 xref: UniGene:Hs.515329 xref: UniGene:Hs.554762 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005751 ! RL22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005503 name: RPL24_human def: "60S ribosomal protein L24 gene" [UniProtKB:P83731] xref: EMBL:AB007177 xref: EMBL:AB061828 xref: EMBL:BC000690 xref: EMBL:BC070193 xref: EMBL:CR456729 xref: EMBL:M94314 xref: HGNC:HGNC:10325 xref: UniGene:Hs.477028 xref: UniGene:Hs.649475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005856 ! RL24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005504 name: RPL27_human def: "60S ribosomal protein L27 gene" [UniProtKB:P61353] xref: EMBL:AB061851 xref: EMBL:BC001700 xref: EMBL:BC002588 xref: EMBL:BC007273 xref: EMBL:BC010026 xref: EMBL:BC098560 xref: EMBL:L05094 xref: EMBL:L19527 xref: HGNC:HGNC:10328 xref: UniGene:Hs.514196 xref: UniGene:Hs.660076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005859 ! RL27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005505 name: RPL28_human def: "60S ribosomal protein L28 gene" [UniProtKB:P46779] xref: EMBL:BC010173 xref: EMBL:BC010182 xref: EMBL:BC011582 xref: EMBL:CR457024 xref: EMBL:U14969 xref: HGNC:HGNC:10330 xref: UniGene:Hs.652114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005853 ! RL28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005506 name: RPL37A_human def: "60S ribosomal protein L37a gene" [UniProtKB:P61513] xref: EMBL:BC000555 xref: EMBL:BC014262 xref: EMBL:BC016748 xref: EMBL:BC082239 xref: EMBL:L06499 xref: EMBL:L22154 xref: EMBL:X66699 xref: HGNC:HGNC:10348 xref: UniGene:Hs.433701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006231 ! RL37A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005507 name: RPL4_human def: "60S ribosomal protein L4 gene" [UniProtKB:P36578] synonym: "RPL1" EXACT [UniProtKB:P36578] xref: EMBL:AB061820 xref: EMBL:BC001365 xref: EMBL:BC005817 xref: EMBL:BC007748 xref: EMBL:BC007996 xref: EMBL:BC009888 xref: EMBL:BC010151 xref: EMBL:BC014653 xref: EMBL:BC066925 xref: EMBL:BC095427 xref: EMBL:D23660 xref: EMBL:L20868 xref: HGNC:HGNC:10353 xref: UniGene:Hs.186350 xref: UniGene:Hs.644628 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005861 ! RL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005508 name: RPL7A_human def: "60S ribosomal protein L7a gene" [UniProtKB:P62424] synonym: "SURF-3" EXACT [UniProtKB:P62424] synonym: "SURF3" EXACT [UniProtKB:P62424] xref: EMBL:BC005128 xref: EMBL:BC021979 xref: EMBL:BC023594 xref: EMBL:BC023624 xref: EMBL:BC071900 xref: EMBL:BC071901 xref: EMBL:BC073802 xref: EMBL:M36072 xref: EMBL:X06705 xref: EMBL:X52138 xref: EMBL:X61923 xref: HGNC:HGNC:10364 xref: UniGene:Hs.499839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005761 ! RL7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005509 name: RPL7_human def: "60S ribosomal protein L7 gene" [UniProtKB:P18124] xref: EMBL:BC006095 xref: EMBL:BC008850 xref: EMBL:BC009599 xref: EMBL:BC071671 xref: EMBL:BC071894 xref: EMBL:BC071895 xref: EMBL:BC087837 xref: EMBL:BC106056 xref: EMBL:CR456773 xref: EMBL:L16558 xref: EMBL:X52967 xref: EMBL:X57958 xref: EMBL:X57959 xref: HGNC:HGNC:10363 xref: UniGene:Hs.421257 xref: UniGene:Hs.571841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005746 ! RL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005510 name: RPL8_human def: "60S ribosomal protein L8 gene" [UniProtKB:P62917] xref: EMBL:AB007168 xref: EMBL:AB061821 xref: EMBL:BC000047 xref: EMBL:BC000077 xref: EMBL:BC012197 xref: EMBL:BC013104 xref: EMBL:BC093064 xref: EMBL:BT007379 xref: EMBL:CR457046 xref: EMBL:Z28407 xref: HGNC:HGNC:10368 xref: UniGene:Hs.178551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005860 ! RL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005511 name: RPLP0_human def: "60S acidic ribosomal protein P0 gene" [UniProtKB:P05388] xref: EMBL:AB007187 xref: EMBL:AC004263 xref: EMBL:BC000087 xref: EMBL:BC000345 xref: EMBL:BC000752 xref: EMBL:BC001127 xref: EMBL:BC001834 xref: EMBL:BC003655 xref: EMBL:BC005863 xref: EMBL:BC008092 xref: EMBL:BC008594 xref: EMBL:BC009867 xref: EMBL:BC015173 xref: EMBL:BC015690 xref: EMBL:M17885 xref: HGNC:HGNC:10371 xref: UniGene:Hs.546285 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005762 ! RLA0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005512 name: RPLP1_human def: "60S acidic ribosomal protein P1 gene" [UniProtKB:P05386] synonym: "RRP1" EXACT [UniProtKB:P05386] xref: EMBL:AB061836 xref: EMBL:BC003369 xref: EMBL:BC007590 xref: EMBL:M17886 xref: HGNC:HGNC:10372 xref: UniGene:Hs.356502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005770 ! RLA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005513 name: RPLP2_human def: "60S acidic ribosomal protein P2 gene" [UniProtKB:P05387] synonym: "D11S2243E" EXACT [UniProtKB:P05387] synonym: "RPP2" EXACT [UniProtKB:P05387] xref: EMBL:AB061837 xref: EMBL:BC005354 xref: EMBL:BC005920 xref: EMBL:BC007573 xref: EMBL:BC062314 xref: EMBL:M17887 xref: HGNC:HGNC:10377 xref: UniGene:Hs.437594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005864 ! RLA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005514 name: MRPL20_human def: "39S ribosomal protein L20, mitochondrial precursor gene" [UniProtKB:Q9BYC9] xref: EMBL:AB049644 xref: EMBL:AL391244 xref: EMBL:BC009515 xref: EMBL:BC014316 xref: EMBL:BC059945 xref: HGNC:HGNC:14478 xref: UniGene:Hs.182698 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006248 ! RM20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005515 name: MRPL41_human def: "39S ribosomal protein L41, mitochondrial precursor gene" [UniProtKB:Q8IXM3] synonym: "BMRP" EXACT [UniProtKB:Q8IXM3] synonym: "MRPL27" EXACT [UniProtKB:Q8IXM3] synonym: "PIG3" EXACT [UniProtKB:Q8IXM3] synonym: "RPML27" EXACT [UniProtKB:Q8IXM3] xref: EMBL:AB051625 xref: EMBL:AL365502 xref: EMBL:AY232291 xref: EMBL:BC040035 xref: HGNC:HGNC:14492 xref: UniGene:Hs.44017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001952 ! RM41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005516 name: RMI1_human def: "Protein RMI1 homolog gene" [UniProtKB:Q9H9A7] synonym: "C9orf76" EXACT [UniProtKB:Q9H9A7] xref: EMBL:AK022950 xref: EMBL:AL732446 xref: EMBL:BC039999 xref: EMBL:BC053549 xref: EMBL:BC064937 xref: HGNC:HGNC:25764 xref: UniGene:Hs.284137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005919 ! RMI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005518 name: RNASEN_human def: "Ribonuclease 3 gene" [UniProtKB:Q9NRR4] synonym: "RN3" EXACT [UniProtKB:Q9NRR4] synonym: "RNASE3L" EXACT [UniProtKB:Q9NRR4] xref: EMBL:AF116910 xref: EMBL:AF189011 xref: EMBL:AJ242976 xref: EMBL:AK001121 xref: EMBL:BC041162 xref: EMBL:BC054003 xref: HGNC:HGNC:17904 xref: UniGene:Hs.97997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006026 ! RNC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005519 name: RNF10_human def: "RING finger protein 10 gene" [UniProtKB:Q8N5U6] synonym: "KIAA0262" EXACT [UniProtKB:Q8N5U6] synonym: "RIE2" EXACT [UniProtKB:Q8N5U6] xref: EMBL:AB027196 xref: EMBL:AL389976 xref: EMBL:BC016622 xref: EMBL:BC031596 xref: EMBL:BC101709 xref: EMBL:BC101715 xref: EMBL:BT006974 xref: EMBL:D87451 xref: HGNC:HGNC:10055 xref: UniGene:Hs.442798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006230 ! RNF10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005520 name: RNF31_human def: "RING finger protein 31 gene" [UniProtKB:Q96EP0] synonym: "ZIBRA" EXACT [UniProtKB:Q96EP0] xref: EMBL:AK000973 xref: EMBL:AK027154 xref: EMBL:AK055542 xref: EMBL:AK074144 xref: EMBL:AY256461 xref: EMBL:BC009821 xref: EMBL:BC012077 xref: EMBL:BC017376 xref: HGNC:HGNC:16031 xref: UniGene:Hs.375217 xref: UniGene:Hs.434081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005982 ! RNF31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005521 name: UBOX5_human def: "RING finger protein 37 gene" [UniProtKB:O94941] synonym: "KIAA0860" EXACT [UniProtKB:O94941] synonym: "RNF37" EXACT [UniProtKB:O94941] synonym: "UBCE7IP5" EXACT [UniProtKB:O94941] xref: EMBL:AB020667 xref: EMBL:AL121891 xref: EMBL:BC000515 xref: HGNC:HGNC:17777 xref: UniGene:Hs.654646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005309 ! RNF37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005524 name: ZNRD1_human def: "DNA-directed RNA polymerase I subunit RPA12 gene" [UniProtKB:Q9P1U0] synonym: "RPA12" EXACT [UniProtKB:Q9P1U0] xref: EMBL:AF024617 xref: EMBL:AF230337 xref: EMBL:AF230338 xref: EMBL:AL669914 xref: EMBL:AL671859 xref: EMBL:AL845439 xref: EMBL:BC010898 xref: EMBL:BC050608 xref: EMBL:BX088647 xref: EMBL:CR457109 xref: HGNC:HGNC:13182 xref: UniGene:Hs.57813 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005622 ! RPA12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005525 name: POLR1C_human def: "DNA-directed RNA polymerases I and III subunit RPAC1 gene" [UniProtKB:O15160] synonym: "POLR1E" EXACT [UniProtKB:O15160] xref: EMBL:AF008442 xref: EMBL:AF047441 xref: EMBL:AL355802 xref: EMBL:BC008863 xref: HGNC:HGNC:20194 xref: UniGene:Hs.584839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005246 ! RPAC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005526 name: POLR2C_human def: "DNA-directed RNA polymerase II subunit RPB3 gene" [UniProtKB:P19387] synonym: "A-152E5.7" EXACT [UniProtKB:P19387] xref: EMBL:AC004382 xref: EMBL:AF008443 xref: EMBL:AJ224143 xref: EMBL:AJ224144 xref: EMBL:BC000409 xref: EMBL:BC003159 xref: EMBL:BC028157 xref: EMBL:J05448 xref: HGNC:HGNC:9189 xref: UniGene:Hs.79402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006100 ! RPB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005528 name: POLR3F_human def: "DNA-directed RNA polymerase III subunit RPC6 gene" [UniProtKB:Q9H1D9] xref: EMBL:AL121893 xref: EMBL:BC012588 xref: EMBL:U93869 xref: HGNC:HGNC:15763 xref: UniGene:Hs.472227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006101 ! RPC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005529 name: RPS10_human def: "40S ribosomal protein S10 gene" [UniProtKB:P46783] xref: EMBL:AB007151 xref: EMBL:BC001032 xref: EMBL:BC001955 xref: EMBL:BC005012 xref: EMBL:BC070235 xref: EMBL:BC071946 xref: EMBL:BC073799 xref: EMBL:BX255972 xref: EMBL:U14972 xref: HGNC:HGNC:10383 xref: UniGene:Hs.645317 xref: UniGene:Hs.702925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005749 ! RS10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005530 name: RPS12_human def: "40S ribosomal protein S12 gene" [UniProtKB:P25398] xref: EMBL:AB007153 xref: EMBL:X53505 xref: HGNC:HGNC:10385 xref: UniGene:Hs.546289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005767 ! RS12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005531 name: RPS13_human def: "40S ribosomal protein S13 gene" [UniProtKB:P62277] xref: EMBL:BC000475 xref: EMBL:BC006772 xref: EMBL:BC029732 xref: EMBL:BC066322 xref: EMBL:BC100032 xref: EMBL:D88010 xref: EMBL:L01124 xref: EMBL:L05090 xref: EMBL:X79239 xref: HGNC:HGNC:10386 xref: UniGene:Hs.446588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005748 ! RS13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005532 name: RPS18_human def: "40S ribosomal protein S18 gene" [UniProtKB:P62269] synonym: "D6S218E" EXACT [UniProtKB:P62269] xref: EMBL:AL031228 xref: EMBL:X69150 xref: HGNC:HGNC:10401 xref: UniGene:Hs.627414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005763 ! RS18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005533 name: RPS19_human def: "40S ribosomal protein S19 gene" [UniProtKB:P39019] xref: EMBL:AB007155 xref: EMBL:AF092906 xref: EMBL:AF092907 xref: EMBL:BC000023 xref: EMBL:BC007615 xref: EMBL:BC018616 xref: EMBL:M81757 xref: HGNC:HGNC:10402 xref: UniGene:Hs.438429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005744 ! RS19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005534 name: RPS20_human def: "40S ribosomal protein S20 gene" [UniProtKB:P60866] xref: EMBL:AB007156 xref: EMBL:AB061842 xref: EMBL:BC007507 xref: EMBL:BC087850 xref: EMBL:L06498 xref: HGNC:HGNC:10405 xref: UniGene:Hs.8102 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005563 ! RS20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005535 name: RPS24_human def: "40S ribosomal protein S24 gene" [UniProtKB:P62847] xref: EMBL:BC000523 xref: EMBL:BC003149 xref: EMBL:BC071926 xref: EMBL:M31520 xref: EMBL:U12202 xref: HGNC:HGNC:10411 xref: UniGene:Hs.356794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005726 ! RS24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005536 name: RPS3A_human def: "40S ribosomal protein S3a gene" [UniProtKB:P61247] synonym: "MFTL" EXACT [UniProtKB:P61247] xref: EMBL:AB007148 xref: EMBL:BC000204 xref: EMBL:BC001708 xref: EMBL:BC004981 xref: EMBL:BC006298 xref: EMBL:BC009219 xref: EMBL:BC009404 xref: EMBL:BC017123 xref: EMBL:BC019072 xref: EMBL:BC030161 xref: EMBL:BC070211 xref: EMBL:BC071916 xref: EMBL:L13802 xref: EMBL:M77234 xref: EMBL:M84711 xref: EMBL:X87373 xref: HGNC:HGNC:10421 xref: UniGene:Hs.356572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005768 ! RS3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005537 name: RPS4X_human def: "40S ribosomal protein S4, X isoform gene" [UniProtKB:P62701] synonym: "CCG2" EXACT [UniProtKB:P62701] synonym: "RPS4" EXACT [UniProtKB:P62701] synonym: "SCAR" EXACT [UniProtKB:P62701] xref: EMBL:AF041428 xref: EMBL:BC000472 xref: EMBL:BC071662 xref: EMBL:BC100903 xref: EMBL:BC100904 xref: EMBL:CR456735 xref: EMBL:M22146 xref: EMBL:M58458 xref: EMBL:Z70767 xref: HGNC:HGNC:10424 xref: UniGene:Hs.446628 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001691 ! RS4X_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005538 name: RPS7_human def: "40S ribosomal protein S7 gene" [UniProtKB:P62081] xref: EMBL:BC002866 xref: EMBL:BC061901 xref: EMBL:BC071919 xref: EMBL:M77233 xref: EMBL:Z25749 xref: HGNC:HGNC:10440 xref: UniGene:Hs.534346 xref: UniGene:Hs.546287 xref: UniGene:Hs.646582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005758 ! RS7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005539 name: RPS8_human def: "40S ribosomal protein S8 gene" [UniProtKB:P62241] synonym: "OK/SW-cl.83" EXACT [UniProtKB:P62241] xref: EMBL:AB062401 xref: EMBL:BC070875 xref: EMBL:X67247 xref: HGNC:HGNC:10441 xref: UniGene:Hs.512675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005734 ! RS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005540 name: RPS9_human def: "40S ribosomal protein S9 gene" [UniProtKB:P46781] xref: EMBL:AB007150 xref: EMBL:AB061839 xref: EMBL:BC000802 xref: EMBL:BC007410 xref: EMBL:BC007434 xref: EMBL:BC007857 xref: EMBL:BC068055 xref: EMBL:BC071940 xref: EMBL:BC096756 xref: EMBL:U14971 xref: HGNC:HGNC:10442 xref: UniGene:Hs.467284 xref: UniGene:Hs.546288 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005750 ! RS9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005541 name: SNRPN_human def: "Small nuclear ribonucleoprotein-associated protein N gene" [UniProtKB:P63162] synonym: "HCERN3" EXACT [UniProtKB:P63162] synonym: "SMN" EXACT [UniProtKB:P63162] xref: EMBL:AF400432 xref: EMBL:BC000611 xref: EMBL:BC003180 xref: EMBL:BC024777 xref: EMBL:BC025178 xref: EMBL:CR450350 xref: EMBL:J04615 xref: EMBL:U41303 xref: EMBL:X15892 xref: HGNC:HGNC:11164 xref: UniGene:Hs.555970 xref: UniGene:Hs.564847 xref: UniGene:Hs.578619 xref: UniGene:Hs.585703 xref: UniGene:Hs.621316 xref: UniGene:Hs.632166 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006111 ! RSMN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005542 name: RSPH1_human def: "Radial spoke head 1 homolog gene" [UniProtKB:Q8WYR4] synonym: "TSA2" EXACT [UniProtKB:Q8WYR4] synonym: "TSGA2" EXACT [UniProtKB:Q8WYR4] xref: EMBL:AB006536 xref: EMBL:AB041016 xref: EMBL:BC101519 xref: EMBL:BC113367 xref: HGNC:HGNC:12371 xref: UniGene:Hs.661069 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002012 ! RSPH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005543 name: RPSA_human def: "40S ribosomal protein SA gene" [UniProtKB:P08865] synonym: "LAMBR" EXACT [UniProtKB:P08865] synonym: "LAMR1" EXACT [UniProtKB:P08865] xref: EMBL:AB007146 xref: EMBL:AF503367 xref: EMBL:BC005391 xref: EMBL:BC008867 xref: EMBL:BC010418 xref: EMBL:BC013827 xref: EMBL:BC034537 xref: EMBL:BC050688 xref: EMBL:BC053370 xref: EMBL:BC062714 xref: EMBL:BC066941 xref: EMBL:BC068062 xref: EMBL:BC070263 xref: EMBL:BC071693 xref: EMBL:BC071968 xref: EMBL:BC071969 xref: EMBL:BC071970 xref: EMBL:BC071971 xref: EMBL:BC073863 xref: EMBL:BC107567 xref: EMBL:BT007219 xref: EMBL:J03799 xref: EMBL:M14199 xref: EMBL:S37431 xref: EMBL:U36484 xref: EMBL:U43901 xref: EMBL:X15005 xref: EMBL:X61156 xref: HGNC:HGNC:6502 xref: UniGene:Hs.449909 xref: UniGene:Hs.560655 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005776 ! RSSA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005544 name: MRPS6_human def: "28S ribosomal protein S6, mitochondrial gene" [UniProtKB:P82932] synonym: "C21orf101" EXACT [UniProtKB:P82932] synonym: "RPMS6" EXACT [UniProtKB:P82932] xref: EMBL:AB049942 xref: EMBL:AB051347 xref: EMBL:AP001719 xref: EMBL:AY061855 xref: EMBL:BC000547 xref: EMBL:BC004976 xref: EMBL:BC010076 xref: EMBL:BC051302 xref: HGNC:HGNC:14051 xref: UniGene:Hs.302742 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006208 ! RT06_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005545 name: MRPS12_human def: "28S ribosomal protein S12, mitochondrial precursor gene" [UniProtKB:O15235] synonym: "RPMS12" EXACT [UniProtKB:O15235] synonym: "RPSM12" EXACT [UniProtKB:O15235] xref: EMBL:AF058761 xref: EMBL:BC001617 xref: EMBL:BC006424 xref: EMBL:BC007499 xref: EMBL:Y11681 xref: HGNC:HGNC:10380 xref: UniGene:Hs.411125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006095 ! RT12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005546 name: MRPS26_human def: "28S ribosomal protein S26, mitochondrial precursor gene" [UniProtKB:Q9BYN8] synonym: "C20orf193" EXACT [UniProtKB:Q9BYN8] synonym: "RPMS13" EXACT [UniProtKB:Q9BYN8] xref: EMBL:AB051354 xref: EMBL:AL121905 xref: EMBL:BC013018 xref: HGNC:HGNC:14045 xref: UniGene:Hs.18946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006288 ! RT26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005547 name: RUNX3_human def: "Runt-related transcription factor 3 gene" [UniProtKB:Q13761] synonym: "AML2" EXACT [UniProtKB:Q13761] synonym: "CBFA3" EXACT [UniProtKB:Q13761] synonym: "PEBP2A3" EXACT [UniProtKB:Q13761] xref: EMBL:AL023096 xref: EMBL:BC013362 xref: EMBL:U14520 xref: EMBL:X79550 xref: EMBL:Z35278 xref: HGNC:HGNC:10473 xref: UniGene:Hs.170019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001766 ! RUNX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005548 name: RUVBL1_human def: "RuvB-like 1 gene" [UniProtKB:Q9Y265] synonym: "INO80H" EXACT [UniProtKB:Q9Y265] synonym: "NMP238" EXACT [UniProtKB:Q9Y265] synonym: "TIP49" EXACT [UniProtKB:Q9Y265] synonym: "TIP49A" EXACT [UniProtKB:Q9Y265] xref: EMBL:AB012122 xref: EMBL:AF070735 xref: EMBL:AF099084 xref: EMBL:AF380343 xref: EMBL:AF380344 xref: EMBL:AJ010058 xref: EMBL:AK222563 xref: EMBL:AK222575 xref: EMBL:BC002993 xref: EMBL:BC012886 xref: EMBL:BT007057 xref: EMBL:DQ469310 xref: EMBL:Y18418 xref: HGNC:HGNC:10474 xref: UniGene:Hs.272822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002249 ! RUVB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005549 name: RUVBL2_human def: "RuvB-like 2 gene" [UniProtKB:Q9Y230] synonym: "CGI-46" EXACT [UniProtKB:Q9Y230] synonym: "INO80J" EXACT [UniProtKB:Q9Y230] synonym: "TIP48" EXACT [UniProtKB:Q9Y230] synonym: "TIP49B" EXACT [UniProtKB:Q9Y230] xref: EMBL:AB024301 xref: EMBL:AF124607 xref: EMBL:AF151804 xref: EMBL:AF155138 xref: EMBL:AK074542 xref: EMBL:AL136743 xref: EMBL:BC000428 xref: EMBL:BC004531 xref: EMBL:BC008355 xref: EMBL:CR533507 xref: EMBL:Y18417 xref: HGNC:HGNC:10475 xref: UniGene:Hs.515846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005364 ! RUVB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005550 name: SNRPG_human def: "Small nuclear ribonucleoprotein G gene" [UniProtKB:P62308] synonym: "PBSCG" EXACT [UniProtKB:P62308] xref: EMBL:AC079338 xref: EMBL:BC000070 xref: EMBL:BC022432 xref: EMBL:BC066302 xref: EMBL:BC070166 xref: EMBL:BC071880 xref: EMBL:BC106055 xref: EMBL:CH471053 xref: EMBL:CR456918 xref: EMBL:X85373 xref: HGNC:HGNC:11163 xref: UniGene:Hs.465167 xref: UniGene:Hs.516076 xref: UniGene:Hs.631639 xref: UniGene:Hs.654528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005495 ! RUXG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005551 name: S100B_human def: "Protein S100-B gene" [UniProtKB:P04271] xref: EMBL:AP000339 xref: EMBL:BC001766 xref: EMBL:CR542123 xref: EMBL:M59487 xref: EMBL:M59488 xref: HGNC:HGNC:10500 xref: UniGene:Hs.422181 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005378 ! S100B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005552 name: S100A6_human def: "Protein S100-A6 gene" [UniProtKB:P06703] synonym: "CACY" EXACT [UniProtKB:P06703] xref: EMBL:AY034480 xref: EMBL:BC001431 xref: EMBL:BC009017 xref: EMBL:BT006965 xref: EMBL:BX470102 xref: EMBL:J02763 xref: EMBL:M14300 xref: EMBL:M18981 xref: HGNC:HGNC:10496 xref: UniGene:Hs.275243 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001494 ! S10A6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005553 name: S100A8_human def: "Protein S100-A8 gene" [UniProtKB:P05109] synonym: "CAGA" EXACT [UniProtKB:P05109] synonym: "CFAG" EXACT [UniProtKB:P05109] synonym: "MRP8" EXACT [UniProtKB:P05109] xref: EMBL:AL591704 xref: EMBL:BC005928 xref: EMBL:BT007378 xref: EMBL:CR407674 xref: EMBL:M21005 xref: EMBL:X06234 xref: EMBL:Y00278 xref: HGNC:HGNC:10498 xref: UniGene:Hs.416073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006159 ! S10A8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005554 name: S100A9_human def: "Protein S100-A9 gene" [UniProtKB:P06702] synonym: "CAGB" EXACT [UniProtKB:P06702] synonym: "CFAG" EXACT [UniProtKB:P06702] synonym: "MRP14" EXACT [UniProtKB:P06702] xref: EMBL:AF237581 xref: EMBL:AF237582 xref: EMBL:AL591704 xref: EMBL:BC047681 xref: EMBL:CR542207 xref: EMBL:CR542224 xref: EMBL:M21064 xref: EMBL:M26311 xref: EMBL:X06233 xref: HGNC:HGNC:10499 xref: UniGene:Hs.112405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005461 ! S10A9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005555 name: S100A11_human def: "Protein S100-A11 gene" [UniProtKB:P31949] synonym: "MLN70" EXACT [UniProtKB:P31949] synonym: "S100C" EXACT [UniProtKB:P31949] xref: EMBL:AL591893 xref: EMBL:BC001410 xref: EMBL:BC014354 xref: EMBL:BT009912 xref: EMBL:D38583 xref: EMBL:D49355 xref: EMBL:D50374 xref: EMBL:X80201 xref: HGNC:HGNC:10488 xref: UniGene:Hs.417004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005825 ! S10AB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005558 name: SAC3D1_human def: "SAC3 domain-containing protein 1 gene" [UniProtKB:A6NKF1] synonym: "SHD1" EXACT [UniProtKB:A6NKF1] xref: EMBL:AP003068 xref: EMBL:BC007448 xref: HGNC:HGNC:30179 xref: UniGene:Hs.23642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001334 ! SAC31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005559 name: SACS_human def: "Sacsin gene" [UniProtKB:Q9NZJ4] synonym: "KIAA0730" EXACT [UniProtKB:Q9NZJ4] xref: EMBL:AB018273 xref: EMBL:AF193556 xref: EMBL:AK090599 xref: EMBL:AL157766 xref: EMBL:BX640926 xref: EMBL:CR749427 xref: HGNC:HGNC:10519 xref: UniGene:Hs.159492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005994 ! SACS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005560 name: SAE1_human def: "SUMO-activating enzyme subunit 1 gene" [UniProtKB:Q9UBE0] synonym: "AOS1" EXACT [UniProtKB:Q9UBE0] synonym: "SUA1" EXACT [UniProtKB:Q9UBE0] synonym: "UBLE1A" EXACT [UniProtKB:Q9UBE0] xref: EMBL:AF046025 xref: EMBL:AF090385 xref: EMBL:AF110956 xref: EMBL:AF161489 xref: EMBL:BC000344 xref: EMBL:BC003611 xref: EMBL:BC018271 xref: EMBL:BT007290 xref: HGNC:HGNC:30660 xref: UniGene:Hs.515500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006046 ! SAE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005561 name: SAMD3_human def: "Sterile alpha motif domain-containing protein 3 gene" [UniProtKB:Q8N6K7] xref: EMBL:AK091351 xref: EMBL:AK091882 xref: EMBL:AL355581 xref: EMBL:BC029851 xref: EMBL:BC119757 xref: EMBL:BC119758 xref: HGNC:HGNC:21574 xref: UniGene:Hs.440508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005257 ! SAMD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005562 name: SAP18_human def: "Histone deacetylase complex subunit SAP18 gene" [UniProtKB:O00422] synonym: "GIG38" EXACT [UniProtKB:O00422] xref: EMBL:AF153608 xref: EMBL:AL158032 xref: EMBL:AY550970 xref: EMBL:BC030836 xref: EMBL:CR457035 xref: EMBL:U78303 xref: EMBL:U96915 xref: HGNC:HGNC:10530 xref: UniGene:Hs.524899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006113 ! SAP18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005563 name: UTP3_human def: "Something about silencing protein 10 gene" [UniProtKB:Q9NQZ2] synonym: "CRLZ1" EXACT [UniProtKB:Q9NQZ2] synonym: "SAS10" EXACT [UniProtKB:Q9NQZ2] xref: EMBL:AF271212 xref: EMBL:AK026909 xref: EMBL:AL136590 xref: EMBL:BC004546 xref: EMBL:CR533544 xref: HGNC:HGNC:24477 xref: UniGene:Hs.322901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006160 ! SAS10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005564 name: SASS6_human def: "Spindle assembly abnormal protein 6 homolog gene" [UniProtKB:Q6UVJ0] synonym: "SAS6" EXACT [UniProtKB:Q6UVJ0] xref: EMBL:AC093019 xref: EMBL:AL445928 xref: EMBL:AL834265 xref: EMBL:AY359522 xref: HGNC:HGNC:25403 xref: UniGene:Hs.591447 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001918 ! SAS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005565 name: SASH1_human def: "SAM and SH3 domain-containing protein 1 gene" [UniProtKB:O94885] synonym: "KIAA0790" EXACT [UniProtKB:O94885] synonym: "PEPE1" EXACT [UniProtKB:O94885] xref: EMBL:AB018333 xref: EMBL:AJ507735 xref: EMBL:AK024403 xref: EMBL:AY351960 xref: EMBL:AY351961 xref: EMBL:AY351962 xref: EMBL:AY351963 xref: EMBL:AY351964 xref: EMBL:AY351965 xref: EMBL:AY351966 xref: EMBL:AY351967 xref: EMBL:AY351968 xref: EMBL:AY351969 xref: EMBL:AY351970 xref: EMBL:AY351971 xref: EMBL:AY351972 xref: EMBL:AY351973 xref: EMBL:AY351974 xref: EMBL:AY351975 xref: EMBL:AY351976 xref: EMBL:AY351977 xref: EMBL:AY351978 xref: EMBL:AY351979 xref: EMBL:BC028303 xref: EMBL:BN000088 xref: HGNC:HGNC:19182 xref: UniGene:Hs.193133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001444 ! SASH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005566 name: SAT1_human def: "Diamine acetyltransferase 1 gene" [UniProtKB:P21673] synonym: "SAT" EXACT [UniProtKB:P21673] xref: EMBL:BC002503 xref: EMBL:BC008424 xref: EMBL:BT006825 xref: EMBL:M55580 xref: EMBL:M77693 xref: EMBL:U40369 xref: EMBL:Z14136 xref: HGNC:HGNC:10540 xref: UniGene:Hs.28491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006107 ! SAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005567 name: SATB1_human def: "DNA-binding protein SATB1 gene" [UniProtKB:Q01826] xref: EMBL:BC001744 xref: EMBL:M97287 xref: HGNC:HGNC:10541 xref: UniGene:Hs.517717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005191 ! SATB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005568 name: SELENBP1_human def: "Selenium-binding protein 1 gene" [UniProtKB:Q13228] synonym: "SBP" EXACT [UniProtKB:Q13228] xref: EMBL:AL391069 xref: EMBL:BC009084 xref: EMBL:CH471121 xref: EMBL:CR456852 xref: EMBL:U29091 xref: HGNC:HGNC:10719 xref: UniGene:Hs.632460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006083 ! SBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005569 name: SEC23A_human def: "Protein transport protein Sec23A gene" [UniProtKB:Q15436] xref: EMBL:AL109628 xref: EMBL:BC036649 xref: EMBL:X97064 xref: HGNC:HGNC:10701 xref: UniGene:Hs.272927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005583 ! SC23A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005570 name: SCAMP1_human def: "Secretory carrier-associated membrane protein 1 gene" [UniProtKB:O15126] synonym: "SCAMP" EXACT [UniProtKB:O15126] xref: EMBL:AF005037 xref: EMBL:AF038966 xref: EMBL:BC009787 xref: EMBL:BC015065 xref: EMBL:BC034048 xref: HGNC:HGNC:10563 xref: UniGene:Hs.482587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005624 ! SCAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005571 name: SCFD1_human def: "Sec1 family domain-containing protein 1 gene" [UniProtKB:Q8WVM8] synonym: "C14orf163" EXACT [UniProtKB:Q8WVM8] synonym: "FKSG23" EXACT [UniProtKB:Q8WVM8] synonym: "KIAA0917" EXACT [UniProtKB:Q8WVM8] synonym: "STXBP1L2" EXACT [UniProtKB:Q8WVM8] xref: EMBL:AB020724 xref: EMBL:AF067205 xref: EMBL:AF086916 xref: EMBL:AF092139 xref: EMBL:AF110646 xref: EMBL:AF319958 xref: EMBL:BC017734 xref: HGNC:HGNC:20726 xref: UniGene:Hs.369168 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006349 ! SCFD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005572 name: CHGB_human def: "Secretogranin-1 precursor gene" [UniProtKB:P05060] synonym: "SCG1" EXACT [UniProtKB:P05060] xref: EMBL:AB209712 xref: EMBL:AK289386 xref: EMBL:AL035461 xref: EMBL:BC000375 xref: EMBL:CH471133 xref: EMBL:CR456726 xref: EMBL:Y00064 xref: HGNC:HGNC:1930 xref: UniGene:Hs.516874 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006217 ! SCG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005573 name: SCN5A_human def: "Sodium channel protein type 5 subunit alpha gene" [UniProtKB:Q14524] xref: EMBL:AP006241 xref: EMBL:M77235 xref: HGNC:HGNC:10593 xref: UniGene:Hs.517898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006346 ! SCN5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005574 name: SCNM1_human def: "Sodium channel modifier 1 gene" [UniProtKB:Q9BWG6] xref: EMBL:AK056322 xref: EMBL:AL592424 xref: EMBL:BC000264 xref: HGNC:HGNC:23136 xref: UniGene:Hs.432360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005251 ! SCNM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005575 name: PPBP_human def: "Platelet basic protein precursor gene" [UniProtKB:P02775] synonym: "CTAP3" EXACT [UniProtKB:P02775] synonym: "CXCL7" EXACT [UniProtKB:P02775] synonym: "SCYB7" EXACT [UniProtKB:P02775] synonym: "TGB1" EXACT [UniProtKB:P02775] synonym: "THBGB1" EXACT [UniProtKB:P02775] xref: EMBL:AC097709 xref: EMBL:AF349466 xref: EMBL:BC028217 xref: EMBL:CR456805 xref: EMBL:M54995 xref: HGNC:HGNC:9240 xref: UniGene:Hs.2164 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035955 ! CXCL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005576 name: SDC2_human def: "Syndecan-2 precursor gene" [UniProtKB:P34741] synonym: "HSPG1" EXACT [UniProtKB:P34741] xref: EMBL:AK025488 xref: EMBL:BC049836 xref: EMBL:J04621 xref: HGNC:HGNC:10659 xref: UniGene:Hs.1501 xref: UniGene:Hs.598247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005445 ! SDC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005577 name: SUDS3_human def: "Sin3 histone deacetylase corepressor complex component SDS3 gene" [UniProtKB:Q9H7L9] synonym: "SAP45" EXACT [UniProtKB:Q9H7L9] synonym: "SDS3" EXACT [UniProtKB:Q9H7L9] xref: EMBL:AK023801 xref: EMBL:AK024460 xref: EMBL:BC030252 xref: EMBL:BC098404 xref: HGNC:HGNC:29545 xref: UniGene:Hs.416630 xref: UniGene:Hs.602312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005694 ! SDS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005578 name: SEC13_human def: "Protein SEC13 homolog gene" [UniProtKB:P55735] synonym: "D3S1231E" EXACT [UniProtKB:P55735] synonym: "SEC13L1" EXACT [UniProtKB:P55735] synonym: "SEC13R" EXACT [UniProtKB:P55735] xref: EMBL:BC002634 xref: EMBL:BC006167 xref: EMBL:BC091506 xref: EMBL:L09260 xref: HGNC:HGNC:10697 xref: UniGene:Hs.166924 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005452 ! SEC13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005579 name: SENP5_human def: "Sentrin-specific protease 5 gene" [UniProtKB:Q96HI0] synonym: "FKSG45" EXACT [UniProtKB:Q96HI0] xref: EMBL:AF335474 xref: EMBL:BC008589 xref: EMBL:BC030705 xref: HGNC:HGNC:28407 xref: UniGene:Hs.240770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002041 ! SENP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005580 name: SENP7_human def: "Sentrin-specific protease 7 gene" [UniProtKB:Q9BQF6] synonym: "KIAA1707" EXACT [UniProtKB:Q9BQF6] synonym: "SSP2" EXACT [UniProtKB:Q9BQF6] synonym: "SUSP2" EXACT [UniProtKB:Q9BQF6] xref: EMBL:AB051494 xref: EMBL:AF199458 xref: EMBL:AF217504 xref: EMBL:AL136599 xref: EMBL:BX537943 xref: HGNC:HGNC:30402 xref: UniGene:Hs.529551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006018 ! SENP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005581 name: SEPT10_human def: "Septin-10 gene" [UniProtKB:Q9P0V9] xref: EMBL:AC140485 xref: EMBL:AF146760 xref: EMBL:AK021681 xref: EMBL:BC020502 xref: EMBL:BC050345 xref: HGNC:HGNC:14349 xref: UniGene:Hs.469615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002183 ! SEP10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005582 name: SEPT11_human def: "Septin-11 gene" [UniProtKB:Q9NVA2] xref: EMBL:AK001711 xref: EMBL:AK027633 xref: EMBL:BC008083 xref: EMBL:BC063615 xref: HGNC:HGNC:25589 xref: UniGene:Hs.128199 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002169 ! SEP11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005583 name: SEPT14_human def: "Septin-14 gene" [UniProtKB:Q6ZU15] xref: EMBL:AC092647 xref: EMBL:AK126048 xref: HGNC:HGNC:33280 xref: UniGene:Hs.453629 xref: UniGene:Hs.700061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001925 ! SEP14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005584 name: SEPT1_human def: "Septin-1 gene" [UniProtKB:Q8WYJ6] synonym: "DIFF6" EXACT [UniProtKB:Q8WYJ6] synonym: "PNUTL3" EXACT [UniProtKB:Q8WYJ6] xref: EMBL:AF085235 xref: EMBL:AF308288 xref: EMBL:AY034176 xref: EMBL:BC012161 xref: HGNC:HGNC:2879 xref: UniGene:Hs.632176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002011 ! SEPT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005585 name: SEPT2_human def: "Septin-2 gene" [UniProtKB:Q15019] synonym: "DIFF6" EXACT [UniProtKB:Q15019] synonym: "KIAA0158" EXACT [UniProtKB:Q15019] synonym: "NEDD5" EXACT [UniProtKB:Q15019] xref: EMBL:AF038404 xref: EMBL:BC014455 xref: EMBL:BC033559 xref: EMBL:D28540 xref: EMBL:D63878 xref: HGNC:HGNC:7729 xref: UniGene:Hs.335057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001800 ! SEPT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005586 name: SEPT3_human def: "Neuronal-specific septin-3 gene" [UniProtKB:Q9UH03] synonym: "SEP3" EXACT [UniProtKB:Q9UH03] xref: EMBL:AB209152 xref: EMBL:AF285107 xref: EMBL:AF285108 xref: EMBL:AF285109 xref: EMBL:AL833942 xref: EMBL:BC111779 xref: EMBL:CR456572 xref: EMBL:Z99716 xref: HGNC:HGNC:10750 xref: UniGene:Hs.120483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002198 ! SEPT3_HUMAN relationship: codes_for CCO:B0041227 ! B1AHR1_HUMAN relationship: codes_for CCO:B0041710 ! B1AHR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005587 name: SEPT4_human def: "Septin-4 gene" [UniProtKB:O43236] synonym: "hucep-7" EXACT [UniProtKB:O43236] synonym: "PNUTL2" EXACT [UniProtKB:O43236] xref: EMBL:AB008753 xref: EMBL:AF035811 xref: EMBL:AF073312 xref: EMBL:BC018056 xref: EMBL:CH471109 xref: EMBL:CR457111 xref: EMBL:D89278 xref: EMBL:U88829 xref: EMBL:U88870 xref: HGNC:HGNC:9165 xref: UniGene:Hs.287518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001382 ! SEPT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005588 name: SEPT5_human def: "Septin-5 gene" [UniProtKB:Q99719] synonym: "PNUTL1" EXACT [UniProtKB:Q99719] xref: EMBL:AF006988 xref: EMBL:BC025261 xref: EMBL:CR456545 xref: EMBL:U74628 xref: EMBL:Y11593 xref: HGNC:HGNC:9164 xref: UniGene:Hs.283743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002079 ! Q99648_HUMAN relationship: codes_for CCO:B0002085 ! SEPT5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005589 name: SEPT6_human def: "Septin-6 gene" [UniProtKB:Q14141] synonym: "KIAA0128" EXACT [UniProtKB:Q14141] synonym: "SEP2" EXACT [UniProtKB:Q14141] xref: EMBL:AC004913 xref: EMBL:AC005052 xref: EMBL:AF397023 xref: EMBL:AF403058 xref: EMBL:AF403059 xref: EMBL:AF403060 xref: EMBL:AF403061 xref: EMBL:AF403062 xref: EMBL:AK290977 xref: EMBL:AK299273 xref: EMBL:AL355348 xref: EMBL:AY005981 xref: EMBL:AY034177 xref: EMBL:BC009291 xref: EMBL:BC011922 xref: EMBL:BC036240 xref: EMBL:CH471161 xref: EMBL:D50918 xref: HGNC:HGNC:15848 xref: UniGene:Hs.496666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001775 ! SEPT6_HUMAN relationship: codes_for CCO:B0033797 ! Q548C9_HUMAN relationship: codes_for CCO:B0033798 ! Q541S4_HUMAN relationship: codes_for CCO:B0041234 ! B1AMS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005590 name: SEPT7_human def: "Septin-7 gene" [UniProtKB:Q16181] synonym: "CDC10" EXACT [UniProtKB:Q16181] xref: EMBL:BC067264 xref: EMBL:BC093640 xref: EMBL:BC093642 xref: EMBL:S72008 xref: HGNC:HGNC:1717 xref: UniGene:Hs.191346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001816 ! SEPT7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005591 name: SEPT8_human def: "Septin-8 gene" [UniProtKB:Q92599] synonym: "KIAA0202" EXACT [UniProtKB:Q92599] xref: EMBL:AC004775 xref: EMBL:AF179995 xref: EMBL:AF440761 xref: EMBL:AF440762 xref: EMBL:AF440763 xref: EMBL:BC001329 xref: EMBL:D86957 xref: HGNC:HGNC:16511 xref: UniGene:Hs.533017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001319 ! A6NC65_HUMAN relationship: codes_for CCO:B0001324 ! A6NFQ9_HUMAN relationship: codes_for CCO:B0001335 ! A6NKP6_HUMAN relationship: codes_for CCO:B0001339 ! A6NMH6_HUMAN relationship: codes_for CCO:B0002015 ! SEPT8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005592 name: SEPT9_human def: "Septin-9 gene" [UniProtKB:Q9UHD8] synonym: "KIAA0991" EXACT [UniProtKB:Q9UHD8] synonym: "MSF" EXACT [UniProtKB:Q9UHD8] xref: EMBL:AB023208 xref: EMBL:AF123052 xref: EMBL:AF142408 xref: EMBL:AF142569 xref: EMBL:AF189712 xref: EMBL:AF189713 xref: EMBL:AJ312319 xref: EMBL:AJ312320 xref: EMBL:AJ312321 xref: EMBL:AJ312322 xref: EMBL:AK022493 xref: EMBL:AL080131 xref: EMBL:BC021192 xref: EMBL:BC054004 xref: EMBL:BC114550 xref: EMBL:BT007215 xref: HGNC:HGNC:7323 xref: UniGene:Hs.440932 xref: UniGene:Hs.672188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001827 ! Q1WWK5_HUMAN relationship: codes_for CCO:B0002201 ! SEPT9_HUMAN relationship: codes_for CCO:B0063524 ! Q9HC74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005593 name: SESN1_human def: "Sestrin-1 gene" [UniProtKB:Q9Y6P5] synonym: "PA26" EXACT [UniProtKB:Q9Y6P5] synonym: "SEST1" EXACT [UniProtKB:Q9Y6P5] xref: EMBL:AF033120 xref: EMBL:AF033121 xref: EMBL:AF033122 xref: EMBL:AK001886 xref: EMBL:BC112036 xref: EMBL:BC113569 xref: EMBL:CH471051 xref: HGNC:HGNC:21595 xref: UniGene:Hs.591336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002266 ! SESN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005594 name: SESN2_human def: "Sestrin-2 gene" [UniProtKB:P58004] synonym: "SEST2" EXACT [UniProtKB:P58004] xref: EMBL:AK025640 xref: EMBL:AK027896 xref: EMBL:AK315710 xref: EMBL:AL136551 xref: EMBL:AL353622 xref: EMBL:AY123223 xref: EMBL:BC013304 xref: EMBL:BC033719 xref: EMBL:CH471059 xref: HGNC:HGNC:20746 xref: UniGene:Hs.469543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001681 ! SESN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005595 name: SESN3_human def: "Sestrin-3 gene" [UniProtKB:P58005] synonym: "SEST3" EXACT [UniProtKB:P58005] xref: EMBL:AC016896 xref: EMBL:AC021174 xref: EMBL:AF086251 xref: EMBL:AK096300 xref: EMBL:BC017296 xref: EMBL:BF328700 xref: EMBL:BG291497 xref: HGNC:HGNC:23060 xref: UniGene:Hs.659934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001682 ! SESN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005596 name: SETD1A_human def: "Histone-lysine N-methyltransferase SETD1A gene" [UniProtKB:O15047] synonym: "KIAA0339" EXACT [UniProtKB:O15047] synonym: "KMT2F" EXACT [UniProtKB:O15047] synonym: "SET1" EXACT [UniProtKB:O15047] synonym: "SET1A" EXACT [UniProtKB:O15047] xref: EMBL:AB002337 xref: EMBL:AC135048 xref: EMBL:BC027450 xref: EMBL:BC035795 xref: HGNC:HGNC:29010 xref: UniGene:Hs.297483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005613 ! SET1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005597 name: SETDB1_human def: "Histone-lysine N-methyltransferase SETDB1 gene" [UniProtKB:Q15047] synonym: "KIAA0067" EXACT [UniProtKB:Q15047] synonym: "KMT1E" EXACT [UniProtKB:Q15047] xref: EMBL:AL590133 xref: EMBL:BC009362 xref: EMBL:BC028671 xref: EMBL:CH471121 xref: EMBL:D31891 xref: HGNC:HGNC:10761 xref: UniGene:Hs.643565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005404 ! SETB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005598 name: SET_human def: "Protein SET gene" [UniProtKB:Q01105] xref: EMBL:AK223556 xref: EMBL:AL356481 xref: EMBL:AY349172 xref: EMBL:BC032749 xref: EMBL:CR536543 xref: EMBL:CR542050 xref: EMBL:D45198 xref: EMBL:EF534308 xref: EMBL:M93651 xref: EMBL:U51924 xref: EMBL:X75091 xref: HGNC:HGNC:10760 xref: UniGene:Hs.436687 xref: UniGene:Hs.596814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005519 ! SET_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005599 name: SFPQ_human def: "Splicing factor, proline- and glutamine-rich gene" [UniProtKB:P23246] synonym: "PSF" EXACT [UniProtKB:P23246] xref: EMBL:AL590434 xref: EMBL:CH471059 xref: EMBL:X16850 xref: EMBL:X70944 xref: HGNC:HGNC:10774 xref: UniGene:Hs.355934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006161 ! SFPQ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005600 name: SFRS1_human def: "Splicing factor, arginine/serine-rich 1 gene" [UniProtKB:Q07955] synonym: "ASF" EXACT [UniProtKB:Q07955] synonym: "OK/SW-cl.3" EXACT [UniProtKB:Q07955] synonym: "SF2" EXACT [UniProtKB:Q07955] synonym: "SF2P33" EXACT [UniProtKB:Q07955] xref: EMBL:AB062124 xref: EMBL:BC010264 xref: EMBL:BC033785 xref: EMBL:M69040 xref: EMBL:M72709 xref: HGNC:HGNC:10780 xref: UniGene:Hs.68714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005487 ! SFRS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005601 name: SGOL1_human def: "Shugoshin-like 1 gene" [UniProtKB:Q5FBB7] synonym: "SGO1" EXACT [UniProtKB:Q5FBB7] xref: EMBL:AB187577 xref: EMBL:AB187578 xref: EMBL:AB187579 xref: EMBL:AB187580 xref: EMBL:AB187581 xref: EMBL:AB187582 xref: EMBL:AB190994 xref: EMBL:AB193056 xref: EMBL:AB193057 xref: EMBL:AB193058 xref: EMBL:AB193059 xref: EMBL:AB193060 xref: EMBL:AB193061 xref: EMBL:AB193062 xref: EMBL:AB193063 xref: EMBL:AB193064 xref: EMBL:AB193065 xref: EMBL:AB193066 xref: EMBL:AF308299 xref: EMBL:BC001339 xref: EMBL:BC017867 xref: EMBL:BC032696 xref: HGNC:HGNC:25088 xref: UniGene:Hs.105153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001847 ! SGOL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005602 name: SGOL2_human def: "Shugoshin-like 2 gene" [UniProtKB:Q562F6] xref: EMBL:AC012459 xref: EMBL:AC080164 xref: EMBL:AK057940 xref: EMBL:AK095291 xref: EMBL:AY094614 xref: EMBL:BC035764 xref: EMBL:BC048349 xref: EMBL:BC092412 xref: HGNC:HGNC:30812 xref: UniGene:Hs.655182 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001840 ! SGOL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005603 name: SGSM3_human def: "Small G protein signaling modulator 3 gene" [UniProtKB:Q96HU1] synonym: "MAP" EXACT [UniProtKB:Q96HU1] synonym: "RABGAPLP" EXACT [UniProtKB:Q96HU1] synonym: "RUTBC3" EXACT [UniProtKB:Q96HU1] xref: EMBL:AB196956 xref: EMBL:AB275763 xref: EMBL:AL022238 xref: EMBL:AL137499 xref: EMBL:AY308849 xref: EMBL:BC008078 xref: EMBL:CH471095 xref: EMBL:CR456441 xref: HGNC:HGNC:25228 xref: UniGene:Hs.474914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002042 ! SGSM3_HUMAN relationship: codes_for CCO:B0041721 ! B0QY80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005604 name: SGTA_human def: "Small glutamine-rich tetratricopeptide repeat-containing protein alpha gene" [UniProtKB:O43765] synonym: "SGT" EXACT [UniProtKB:O43765] xref: EMBL:AC006538 xref: EMBL:AF408399 xref: EMBL:AJ133129 xref: EMBL:AJ223828 xref: EMBL:AL050156 xref: EMBL:BC000390 xref: EMBL:BC002989 xref: EMBL:BC005165 xref: EMBL:BC008885 xref: HGNC:HGNC:10819 xref: UniGene:Hs.203910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006084 ! SGTA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005605 name: SH2D2A_human def: "SH2 domain-containing protein 2A gene" [UniProtKB:Q9NP31] synonym: "SCAP" EXACT [UniProtKB:Q9NP31] synonym: "TSAD" EXACT [UniProtKB:Q9NP31] synonym: "VRAP" EXACT [UniProtKB:Q9NP31] xref: EMBL:AF051325 xref: EMBL:AF097744 xref: EMBL:AF106072 xref: EMBL:AJ000553 xref: EMBL:AK222737 xref: EMBL:AL158169 xref: EMBL:AL590666 xref: EMBL:BC012107 xref: HGNC:HGNC:10821 xref: UniGene:Hs.103527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005476 ! SH22A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005606 name: SH3BP4_human def: "SH3 domain-binding protein 4 gene" [UniProtKB:Q9P0V3] synonym: "BOG25" EXACT [UniProtKB:Q9P0V3] synonym: "EHB10" EXACT [UniProtKB:Q9P0V3] synonym: "TTP" EXACT [UniProtKB:Q9P0V3] xref: EMBL:AC010148 xref: EMBL:AC114814 xref: EMBL:AF015043 xref: EMBL:AF147747 xref: EMBL:BC057396 xref: EMBL:DQ232895 xref: HGNC:HGNC:10826 xref: UniGene:Hs.516777 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002182 ! SH3B4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005607 name: SH3GL1_human def: "Endophilin-A2 gene" [UniProtKB:Q99961] synonym: "CNSA1" EXACT [UniProtKB:Q99961] synonym: "SH3D2B" EXACT [UniProtKB:Q99961] xref: EMBL:AF190465 xref: EMBL:BC001270 xref: EMBL:U65999 xref: EMBL:X99656 xref: HGNC:HGNC:10830 xref: UniGene:Hs.97616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006310 ! SH3G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005608 name: SH3GL2_human def: "Endophilin-A1 gene" [UniProtKB:Q99962] synonym: "CNSA2" EXACT [UniProtKB:Q99962] synonym: "SH3D2A" EXACT [UniProtKB:Q99962] xref: EMBL:AF036268 xref: EMBL:AL133214 xref: EMBL:AL139115 xref: EMBL:BT019682 xref: EMBL:CR542086 xref: EMBL:CR542102 xref: EMBL:X99657 xref: HGNC:HGNC:10831 xref: UniGene:Hs.75149 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006188 ! SH3G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005609 name: SH3GL3_human def: "Endophilin-A3 gene" [UniProtKB:Q99963] synonym: "CNSA3" EXACT [UniProtKB:Q99963] synonym: "SH3D2C" EXACT [UniProtKB:Q99963] xref: EMBL:AF036269 xref: EMBL:AF036270 xref: EMBL:AF036271 xref: EMBL:AF036272 xref: EMBL:X99664 xref: HGNC:HGNC:10832 xref: UniGene:Hs.270055 xref: UniGene:Hs.666365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006187 ! SH3G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005610 name: SHC1_human def: "SHC-transforming protein 1 gene" [UniProtKB:P29353] synonym: "SHC" EXACT [UniProtKB:P29353] synonym: "SHCA" EXACT [UniProtKB:P29353] xref: EMBL:AK292143 xref: EMBL:AK315842 xref: EMBL:AL451085 xref: EMBL:BC014158 xref: EMBL:BC033925 xref: EMBL:CH471121 xref: EMBL:U73377 xref: EMBL:X68148 xref: EMBL:Y09847 xref: HGNC:HGNC:10840 xref: UniGene:Hs.433795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001569 ! SHC1_HUMAN relationship: codes_for CCO:B0015783 ! Q5T188_HUMAN relationship: codes_for CCO:B0015787 ! Q5T182_HUMAN relationship: codes_for CCO:B0015789 ! Q5T187_HUMAN relationship: codes_for CCO:B0015792 ! Q5T181_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005611 name: SHOC2_human def: "Leucine-rich repeat protein SHOC-2 gene" [UniProtKB:Q9UQ13] synonym: "KIAA0862" EXACT [UniProtKB:Q9UQ13] xref: EMBL:AB020669 xref: EMBL:AF054828 xref: EMBL:AF068920 xref: EMBL:BC050445 xref: HGNC:HGNC:15454 xref: UniGene:Hs.104315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005650 ! SHOC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005612 name: SIAH1_human def: "E3 ubiquitin-protein ligase SIAH1 gene" [UniProtKB:Q8IUQ4] synonym: "HUMSIAH" EXACT [UniProtKB:Q8IUQ4] xref: EMBL:AJ400626 xref: EMBL:BC035562 xref: EMBL:BC042550 xref: EMBL:BC044920 xref: EMBL:BX647064 xref: EMBL:EF026094 xref: EMBL:U63295 xref: EMBL:U76247 xref: HGNC:HGNC:10857 xref: UniGene:Hs.295923 xref: UniGene:Hs.700697 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001946 ! SIAH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005613 name: SIAH2_human def: "E3 ubiquitin-protein ligase SIAH2 gene" [UniProtKB:O43255] xref: EMBL:BC013082 xref: EMBL:U76248 xref: EMBL:Y15268 xref: HGNC:HGNC:10858 xref: UniGene:Hs.477959 xref: UniGene:Hs.692394 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001384 ! SIAH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005614 name: SIN3A_human def: "Paired amphipathic helix protein Sin3a gene" [UniProtKB:Q96ST3] xref: EMBL:AF418569 xref: EMBL:AK027559 xref: EMBL:AK074903 xref: EMBL:AK096477 xref: EMBL:AL117513 xref: EMBL:AY044430 xref: EMBL:BC018973 xref: HGNC:HGNC:19353 xref: UniGene:Hs.513039 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005357 ! SIN3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005615 name: SIN3B_human def: "Paired amphipathic helix protein Sin3b gene" [UniProtKB:O75182] synonym: "KIAA0700" EXACT [UniProtKB:O75182] xref: EMBL:AB014600 xref: EMBL:AY706204 xref: EMBL:BC005113 xref: EMBL:BC025026 xref: EMBL:BC063531 xref: HGNC:HGNC:19354 xref: UniGene:Hs.13999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005807 ! SIN3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005616 name: SIPA1_human def: "Signal-induced proliferation-associated protein 1 gene" [UniProtKB:Q96FS4] synonym: "SPA1" EXACT [UniProtKB:Q96FS4] xref: EMBL:AB005666 xref: EMBL:AF029789 xref: EMBL:AF052233 xref: EMBL:AF052234 xref: EMBL:AF052235 xref: EMBL:AF052236 xref: EMBL:AF052237 xref: EMBL:AF052238 xref: EMBL:BC010492 xref: EMBL:BC110353 xref: HGNC:HGNC:10885 xref: UniGene:Hs.530477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002039 ! SIPA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005617 name: SIRT2_human def: "NAD-dependent deacetylase sirtuin-2 gene" [UniProtKB:Q8IXJ6] synonym: "SIR2L" EXACT [UniProtKB:Q8IXJ6] synonym: "SIR2L2" EXACT [UniProtKB:Q8IXJ6] xref: EMBL:AF083107 xref: EMBL:AF095714 xref: EMBL:AF131800 xref: EMBL:AF160214 xref: EMBL:AJ505014 xref: EMBL:AY030277 xref: EMBL:BC003012 xref: EMBL:BC003547 xref: HGNC:HGNC:10886 xref: UniGene:Hs.466693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001951 ! SIRT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005618 name: SKIV2L2_human def: "Superkiller viralicidic activity 2-like 2 gene" [UniProtKB:P42285] synonym: "KIAA0052" EXACT [UniProtKB:P42285] xref: EMBL:BC014669 xref: EMBL:BC028604 xref: EMBL:BC031779 xref: EMBL:BC065258 xref: EMBL:BC104996 xref: EMBL:BC113509 xref: EMBL:BX640789 xref: EMBL:D29641 xref: HGNC:HGNC:18734 xref: UniGene:Hs.274531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005346 ! SK2L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005619 name: SKA1_human def: "Spindle and kinetochore-associated protein 1 gene" [UniProtKB:Q96BD8] synonym: "C18orf24" EXACT [UniProtKB:Q96BD8] xref: EMBL:BC015706 xref: HGNC:HGNC:28109 xref: UniGene:Hs.134726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002032 ! SKA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005620 name: FAM33A_human def: "Spindle and kinetochore-associated protein 2 gene" [UniProtKB:Q8WVK7] synonym: "SKA2" EXACT [UniProtKB:Q8WVK7] xref: EMBL:AC099850 xref: EMBL:BC017873 xref: EMBL:BC106003 xref: HGNC:HGNC:28006 xref: UniGene:Hs.463607 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002003 ! SKA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005621 name: SKIV2L_human def: "Helicase SKI2W gene" [UniProtKB:Q15477] synonym: "DDX13" EXACT [UniProtKB:Q15477] synonym: "SKI2W" EXACT [UniProtKB:Q15477] synonym: "SKIV2" EXACT [UniProtKB:Q15477] synonym: "W" EXACT [UniProtKB:Q15477] xref: EMBL:AF019413 xref: EMBL:U09877 xref: EMBL:X98378 xref: EMBL:Z48796 xref: HGNC:HGNC:10898 xref: UniGene:Hs.89864 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005565 ! SKIV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005623 name: SKP2_human def: "S-phase kinase-associated protein 2 gene" [UniProtKB:Q13309] synonym: "FBXL1" EXACT [UniProtKB:Q13309] xref: EMBL:AB050979 xref: EMBL:AB050980 xref: EMBL:AB050981 xref: EMBL:AY029177 xref: EMBL:BC001441 xref: EMBL:BC007441 xref: EMBL:U33761 xref: HGNC:HGNC:10901 xref: UniGene:Hs.23348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001749 ! SKP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005624 name: SMAD4_human def: "Mothers against decapentaplegic homolog 4 gene" [UniProtKB:Q13485] synonym: "DPC4" EXACT [UniProtKB:Q13485] synonym: "MADH4" EXACT [UniProtKB:Q13485] xref: EMBL:AF045438 xref: EMBL:AF045439 xref: EMBL:AF045440 xref: EMBL:AF045441 xref: EMBL:AF045442 xref: EMBL:AF045443 xref: EMBL:AF045444 xref: EMBL:AF045445 xref: EMBL:AF045446 xref: EMBL:AF045447 xref: EMBL:BC002379 xref: EMBL:U44378 xref: HGNC:HGNC:6770 xref: UniGene:Hs.592888 xref: UniGene:Hs.75862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005322 ! SMAD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005625 name: SMC1A_human def: "Structural maintenance of chromosomes protein 1A gene" [UniProtKB:Q14683] synonym: "DXS423E" EXACT [UniProtKB:Q14683] synonym: "KIAA0178" EXACT [UniProtKB:Q14683] synonym: "SB1.8" EXACT [UniProtKB:Q14683] synonym: "SMC1" EXACT [UniProtKB:Q14683] synonym: "SMC1L1" EXACT [UniProtKB:Q14683] xref: EMBL:AL161779 xref: EMBL:BC112127 xref: EMBL:D80000 xref: EMBL:S78271 xref: EMBL:Z97054 xref: HGNC:HGNC:11111 xref: UniGene:Hs.211602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001790 ! SMC1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005626 name: SMC1B_human def: "Structural maintenance of chromosomes protein 1B gene" [UniProtKB:Q8NDV3] synonym: "SMC1L2" EXACT [UniProtKB:Q8NDV3] xref: EMBL:AJ504806 xref: EMBL:AK125736 xref: EMBL:AL008718 xref: EMBL:AL021391 xref: EMBL:BC126208 xref: HGNC:HGNC:11112 xref: UniGene:Hs.334176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001977 ! SMC1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005627 name: SMC2_human def: "Structural maintenance of chromosomes protein 2 gene" [UniProtKB:O95347] synonym: "CAPE" EXACT [UniProtKB:O95347] synonym: "PRO0324" EXACT [UniProtKB:O95347] synonym: "SMC2L1" EXACT [UniProtKB:O95347] xref: EMBL:AF092563 xref: EMBL:AF113673 xref: EMBL:AL161791 xref: EMBL:AL354938 xref: EMBL:AL833191 xref: EMBL:BC130385 xref: EMBL:BN000163 xref: EMBL:CH471105 xref: HGNC:HGNC:14011 xref: UniGene:Hs.119023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001450 ! SMC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005628 name: SMC3_human def: "Structural maintenance of chromosomes protein 3 gene" [UniProtKB:Q9UQE7] synonym: "BAM" EXACT [UniProtKB:Q9UQE7] synonym: "BMH" EXACT [UniProtKB:Q9UQE7] synonym: "CSPG6" EXACT [UniProtKB:Q9UQE7] synonym: "SMC3L1" EXACT [UniProtKB:Q9UQE7] xref: EMBL:AF020043 xref: EMBL:AF067163 xref: EMBL:AJ005015 xref: EMBL:AL359260 xref: HGNC:HGNC:2468 xref: UniGene:Hs.24485 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002243 ! SMC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005629 name: SMC4_human def: "Structural maintenance of chromosomes protein 4 gene" [UniProtKB:Q9NTJ3] synonym: "CAPC" EXACT [UniProtKB:Q9NTJ3] synonym: "SMC4L1" EXACT [UniProtKB:Q9NTJ3] xref: EMBL:AB019987 xref: EMBL:AC024221 xref: EMBL:AF092564 xref: EMBL:AL136877 xref: EMBL:AL833949 xref: EMBL:CH471052 xref: HGNC:HGNC:14013 xref: UniGene:Hs.58992 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002168 ! SMC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005630 name: SMARCA2_human def: "Probable global transcription activator SNF2L2 gene" [UniProtKB:P51531] synonym: "BRM" EXACT [UniProtKB:P51531] synonym: "SNF2A" EXACT [UniProtKB:P51531] synonym: "SNF2L2" EXACT [UniProtKB:P51531] xref: EMBL:AL138755 xref: EMBL:AL359076 xref: EMBL:CH471071 xref: EMBL:D26155 xref: EMBL:X72889 xref: HGNC:HGNC:11098 xref: UniGene:Hs.298990 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005925 ! SMCA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005631 name: SMARCA4_human def: "Probable global transcription activator SNF2L4 gene" [UniProtKB:P51532] synonym: "BRG1" EXACT [UniProtKB:P51532] synonym: "SNF2B" EXACT [UniProtKB:P51532] synonym: "SNF2L4" EXACT [UniProtKB:P51532] xref: EMBL:AC006127 xref: EMBL:AC011442 xref: EMBL:AC011485 xref: EMBL:AF254822 xref: EMBL:D26156 xref: EMBL:U29175 xref: HGNC:HGNC:11100 xref: UniGene:Hs.327527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005414 ! SMCA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005632 name: SMARCE1_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 gene" [UniProtKB:Q969G3] synonym: "BAF57" EXACT [UniProtKB:Q969G3] xref: EMBL:AF035262 xref: EMBL:BC007082 xref: EMBL:BC011017 xref: EMBL:BC063700 xref: EMBL:BT007176 xref: HGNC:HGNC:11109 xref: UniGene:Hs.696086 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005416 ! SMCE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005633 name: SMN1_human def: "Survival motor neuron protein gene" [UniProtKB:Q16637] synonym: "SMN" EXACT [UniProtKB:Q16637] synonym: "SMNT" EXACT [UniProtKB:Q16637] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006110 ! SMN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005634 name: SMN2_human def: "Survival motor neuron protein gene" [UniProtKB:Q16637] synonym: "SMNC" EXACT [UniProtKB:Q16637] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006110 ! SMN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005635 name: SMO_human def: "Smoothened homolog precursor gene" [UniProtKB:Q99835] synonym: "SMOH" EXACT [UniProtKB:Q99835] xref: EMBL:AF071494 xref: EMBL:AF114819 xref: EMBL:AF114820 xref: EMBL:AF114821 xref: EMBL:AF120103 xref: EMBL:BC009989 xref: EMBL:U84401 xref: HGNC:HGNC:11119 xref: UniGene:Hs.437846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006039 ! SMO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005636 name: SMARCC1_human def: "SWI/SNF complex subunit SMARCC1 gene" [UniProtKB:Q92922] synonym: "BAF155" EXACT [UniProtKB:Q92922] xref: EMBL:BC039843 xref: EMBL:BC065253 xref: EMBL:BC113465 xref: EMBL:BC117213 xref: EMBL:U66615 xref: HGNC:HGNC:11104 xref: UniGene:Hs.476179 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005418 ! SMRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005637 name: SMARCC2_human def: "SWI/SNF complex subunit SMARCC2 gene" [UniProtKB:Q8TAQ2] synonym: "BAF170" EXACT [UniProtKB:Q8TAQ2] xref: EMBL:BC009067 xref: EMBL:BC013045 xref: EMBL:BC026222 xref: EMBL:BT009924 xref: EMBL:U66616 xref: HGNC:HGNC:11105 xref: UniGene:Hs.236030 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005417 ! SMRC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005638 name: SMARCD1_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 gene" [UniProtKB:Q96GM5] synonym: "BAF60A" EXACT [UniProtKB:Q96GM5] xref: EMBL:AF109733 xref: EMBL:BC009368 xref: EMBL:U66617 xref: HGNC:HGNC:11106 xref: UniGene:Hs.79335 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005415 ! SMRD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005639 name: SMARCD2_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 gene" [UniProtKB:Q92925] synonym: "BAF60B" EXACT [UniProtKB:Q92925] synonym: "PRO2451" EXACT [UniProtKB:Q92925] xref: EMBL:AF113019 xref: EMBL:BC018953 xref: EMBL:U66618 xref: HGNC:HGNC:11107 xref: UniGene:Hs.250581 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005419 ! SMRD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005640 name: SMU1_human def: "WD40 repeat-containing protein SMU1 gene" [UniProtKB:Q2TAY7] xref: EMBL:AK001667 xref: EMBL:AK022032 xref: EMBL:AL162590 xref: EMBL:BC002876 xref: EMBL:BC110654 xref: HGNC:HGNC:18247 xref: UniGene:Hs.655351 xref: UniGene:Hs.679417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005691 ! SMU1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005641 name: SNF1LK_human def: "Serine/threonine-protein kinase SNF1-like kinase 1 gene" [UniProtKB:P57059] synonym: "SIK" EXACT [UniProtKB:P57059] xref: EMBL:AB047786 xref: EMBL:AK131076 xref: EMBL:AP001751 xref: EMBL:BC038504 xref: HGNC:HGNC:11142 xref: UniGene:Hs.282113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001680 ! SN1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005642 name: SNF1LK2_human def: "Serine/threonine-protein kinase SNF1-like kinase 2 gene" [UniProtKB:Q9H0K1] synonym: "KIAA0781" EXACT [UniProtKB:Q9H0K1] synonym: "QIK" EXACT [UniProtKB:Q9H0K1] synonym: "SIK2" EXACT [UniProtKB:Q9H0K1] xref: EMBL:AB018324 xref: EMBL:AB084424 xref: EMBL:AL136764 xref: EMBL:BC013612 xref: EMBL:BC078150 xref: EMBL:BC113459 xref: EMBL:BC117183 xref: HGNC:HGNC:21680 xref: UniGene:Hs.269128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005873 ! SN1L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005643 name: SNCAIP_human def: "Synphilin-1 gene" [UniProtKB:Q9Y6H5] xref: EMBL:AF076929 xref: EMBL:AF167301 xref: EMBL:AF167302 xref: EMBL:AF167303 xref: EMBL:AF167304 xref: EMBL:AF167305 xref: EMBL:AF167306 xref: EMBL:CH471086 xref: HGNC:HGNC:11139 xref: UniGene:Hs.426463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006235 ! SNCAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005644 name: SMARCB1_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 gene" [UniProtKB:Q12824] synonym: "INI1" EXACT [UniProtKB:Q12824] synonym: "SNF5L1" EXACT [UniProtKB:Q12824] xref: EMBL:AB017523 xref: EMBL:AJ011737 xref: EMBL:AJ011738 xref: EMBL:CR456581 xref: EMBL:DQ230988 xref: EMBL:U04847 xref: EMBL:Y17118 xref: EMBL:Y17119 xref: EMBL:Y17120 xref: EMBL:Y17121 xref: EMBL:Y17122 xref: EMBL:Y17123 xref: EMBL:Y17124 xref: EMBL:Y17125 xref: EMBL:Y17126 xref: HGNC:HGNC:11103 xref: UniGene:Hs.534350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001732 ! SNF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005645 name: SNIP1_human def: "Smad nuclear-interacting protein 1 gene" [UniProtKB:Q8TAD8] xref: EMBL:AK022615 xref: EMBL:AK027622 xref: EMBL:AY081909 xref: EMBL:BC027040 xref: HGNC:HGNC:30587 xref: UniGene:Hs.471951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005335 ! SNIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005646 name: SART1_human def: "U4/U6.U5 tri-snRNP-associated protein 1 gene" [UniProtKB:O43290] xref: EMBL:AB006198 xref: EMBL:AF109680 xref: EMBL:AF353625 xref: EMBL:AK223016 xref: EMBL:AP006287 xref: EMBL:BC001058 xref: EMBL:BT006637 xref: HGNC:HGNC:10538 xref: UniGene:Hs.502883 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001388 ! SNUT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005647 name: SNX9_human def: "Sorting nexin-9 gene" [UniProtKB:Q9Y5X1] synonym: "SH3PX1" EXACT [UniProtKB:Q9Y5X1] synonym: "SH3PXD3A" EXACT [UniProtKB:Q9Y5X1] xref: EMBL:AF076957 xref: EMBL:AF121859 xref: EMBL:AF131214 xref: EMBL:AF172847 xref: EMBL:AL035634 xref: EMBL:AL139330 xref: EMBL:AL391863 xref: EMBL:BC001084 xref: EMBL:BC005022 xref: HGNC:HGNC:14973 xref: UniGene:Hs.191213 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005559 ! SNX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005648 name: SOCS3_human def: "Suppressor of cytokine signaling 3 gene" [UniProtKB:O14543] synonym: "CIS3" EXACT [UniProtKB:O14543] synonym: "SSI3" EXACT [UniProtKB:O14543] xref: EMBL:AB004904 xref: EMBL:AB006967 xref: EMBL:AF159854 xref: EMBL:BC060858 xref: HGNC:HGNC:19391 xref: UniGene:Hs.527973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006162 ! SOCS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005649 name: SOS1_human def: "Son of sevenless homolog 1 gene" [UniProtKB:Q07889] xref: EMBL:AF441466 xref: EMBL:AF441467 xref: EMBL:AF441468 xref: EMBL:AF441469 xref: EMBL:AF441470 xref: EMBL:AF441471 xref: EMBL:AF441472 xref: EMBL:AF441473 xref: EMBL:AF441474 xref: EMBL:AF441475 xref: EMBL:AF441476 xref: EMBL:AF441477 xref: EMBL:AF441478 xref: EMBL:AF441479 xref: EMBL:AF441480 xref: EMBL:AF441481 xref: EMBL:AF441482 xref: EMBL:L13857 xref: HGNC:HGNC:11187 xref: UniGene:Hs.654397 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005383 ! SOS1_HUMAN relationship: codes_for CCO:B0023961 ! Q8NIA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005650 name: SOS2_human def: "Son of sevenless homolog 2 gene" [UniProtKB:Q07890] xref: EMBL:L13858 xref: EMBL:L20686 xref: HGNC:HGNC:11188 xref: UniGene:Hs.291533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005666 ! SOS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005651 name: SP1_human def: "Transcription factor Sp1 gene" [UniProtKB:P08047] synonym: "TSFP1" EXACT [UniProtKB:P08047] xref: EMBL:AB039286 xref: EMBL:AF252284 xref: EMBL:AF255682 xref: EMBL:AJ272134 xref: EMBL:BC043224 xref: EMBL:BC062539 xref: EMBL:J03133 xref: HGNC:HGNC:11205 xref: UniGene:Hs.620754 xref: UniGene:Hs.649191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005485 ! SP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005652 name: SPAG5_human def: "Sperm-associated antigen 5 gene" [UniProtKB:Q96R06] xref: EMBL:AF063308 xref: EMBL:AF345347 xref: EMBL:AF399910 xref: EMBL:AL122116 xref: EMBL:AL137585 xref: EMBL:BC000322 xref: HGNC:HGNC:13452 xref: UniGene:Hs.514033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002058 ! SPAG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005653 name: SERPINB9_human def: "Serpin B9 gene" [UniProtKB:P50453] synonym: "PI9" EXACT [UniProtKB:P50453] xref: EMBL:AB060690 xref: EMBL:AL133351 xref: EMBL:BC002538 xref: EMBL:BT006673 xref: EMBL:CH471087 xref: EMBL:CR407627 xref: EMBL:L40378 xref: EMBL:U71364 xref: HGNC:HGNC:8955 xref: UniGene:Hs.104879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006108 ! SPB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005655 name: SPC25_human def: "Kinetochore protein Spc25 gene" [UniProtKB:Q9HBM1] synonym: "AD024" EXACT [UniProtKB:Q9HBM1] synonym: "SPBC25" EXACT [UniProtKB:Q9HBM1] xref: EMBL:AC069137 xref: EMBL:AF225416 xref: EMBL:AY456388 xref: EMBL:BC022255 xref: EMBL:CR457197 xref: HGNC:HGNC:24031 xref: UniGene:Hs.421956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002143 ! SPC25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005656 name: SPDYA_human def: "Speedy protein A gene" [UniProtKB:Q5MJ70] synonym: "SPDY1" EXACT [UniProtKB:Q5MJ70] synonym: "SPY1" EXACT [UniProtKB:Q5MJ70] xref: EMBL:AC097720 xref: EMBL:AY820303 xref: EMBL:AY820304 xref: EMBL:BC093005 xref: HGNC:HGNC:30613 xref: UniGene:Hs.511956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001862 ! SPDYA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005657 name: SPDYC_human def: "Speedy protein C gene" [UniProtKB:Q5MJ68] xref: EMBL:AY820305 xref: HGNC:HGNC:32681 xref: UniGene:Hs.450642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001861 ! SPDYC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005658 name: SPG7_human def: "Paraplegin gene" [UniProtKB:Q9UQ90] synonym: "CAR" EXACT [UniProtKB:Q9UQ90] synonym: "CMAR" EXACT [UniProtKB:Q9UQ90] synonym: "PGN" EXACT [UniProtKB:Q9UQ90] xref: EMBL:AF080511 xref: EMBL:AF080512 xref: EMBL:AF080513 xref: EMBL:AF080514 xref: EMBL:AF080515 xref: EMBL:AF080516 xref: EMBL:AF080517 xref: EMBL:AF080518 xref: EMBL:AF080519 xref: EMBL:AF080520 xref: EMBL:AF080521 xref: EMBL:AF080522 xref: EMBL:AF080523 xref: EMBL:AF080524 xref: EMBL:AF080525 xref: EMBL:BC007692 xref: EMBL:BC035929 xref: EMBL:BC036104 xref: EMBL:BC110530 xref: EMBL:BC110531 xref: EMBL:Y16610 xref: HGNC:HGNC:11237 xref: UniGene:Hs.185597 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006236 ! SPG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005659 name: SPHAR_human def: "Protein SPHAR gene" [UniProtKB:Q15513] xref: EMBL:AL117350 xref: EMBL:DQ120096 xref: EMBL:X82554 xref: UniGene:Hs.296169 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001809 ! SPHAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005660 name: SPHK1_human def: "Sphingosine kinase 1 gene" [UniProtKB:Q9NYA1] synonym: "SPHK" EXACT [UniProtKB:Q9NYA1] synonym: "SPK" EXACT [UniProtKB:Q9NYA1] xref: EMBL:AF200328 xref: EMBL:AF238083 xref: EMBL:AF266756 xref: EMBL:AJ245504 xref: EMBL:AK022402 xref: EMBL:AK023393 xref: EMBL:AK292294 xref: EMBL:BC009419 xref: EMBL:BC014439 xref: EMBL:BC030553 xref: EMBL:CH471099 xref: HGNC:HGNC:11240 xref: UniGene:Hs.68061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002176 ! SPHK1_HUMAN relationship: codes_for CCO:B0020756 ! Q96GK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005661 name: SPIN2A_human def: "Spindlin-2A gene" [UniProtKB:Q99865] synonym: "DXF34" EXACT [UniProtKB:Q99865] synonym: "SPIN2" EXACT [UniProtKB:Q99865] xref: EMBL:AL022157 xref: EMBL:BC071694 xref: EMBL:Y09858 xref: HGNC:HGNC:20694 xref: UniGene:Hs.460725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002090 ! SPI2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005662 name: SPIN2B_human def: "Spindlin-2B gene" [UniProtKB:Q9BPZ2] synonym: "SPIN2" EXACT [UniProtKB:Q9BPZ2] xref: EMBL:AF356353 xref: EMBL:AL022157 xref: EMBL:BC000044 xref: EMBL:BC071974 xref: HGNC:HGNC:33147 xref: UniGene:Hs.659479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002093 ! SPI2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005663 name: SPIN1_human def: "Spindlin-1 gene" [UniProtKB:Q9Y657] synonym: "OCR" EXACT [UniProtKB:Q9Y657] synonym: "SPIN" EXACT [UniProtKB:Q9Y657] xref: EMBL:AF087864 xref: EMBL:AF106682 xref: EMBL:AF317228 xref: EMBL:AL136719 xref: EMBL:AL353748 xref: EMBL:BC114515 xref: EMBL:BC114565 xref: EMBL:BT007314 xref: EMBL:CR533484 xref: HGNC:HGNC:11243 xref: UniGene:Hs.146804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002262 ! SPIN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005664 name: SPO11_human def: "Meiotic recombination protein SPO11 gene" [UniProtKB:Q9Y5K1] xref: EMBL:AF149310 xref: EMBL:AF169385 xref: EMBL:AL135939 xref: EMBL:AY957583 xref: EMBL:BC033591 xref: HGNC:HGNC:11250 xref: UniGene:Hs.159737 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001337 ! A6NLT8_HUMAN relationship: codes_for CCO:B0001886 ! Q5TCH6_HUMAN relationship: codes_for CCO:B0001887 ! Q5TCH7_HUMAN relationship: codes_for CCO:B0002256 ! SPO11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005665 name: SPOP_human def: "Speckle-type POZ protein gene" [UniProtKB:O43791] xref: EMBL:AJ000644 xref: EMBL:AK222589 xref: EMBL:BC001269 xref: EMBL:BC003385 xref: HGNC:HGNC:11254 xref: UniGene:Hs.463382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005292 ! SPOP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005666 name: SUPT5H_human def: "Transcription elongation factor SPT5 gene" [UniProtKB:O00267] synonym: "SPT5" EXACT [UniProtKB:O00267] synonym: "SPT5H" EXACT [UniProtKB:O00267] xref: EMBL:AB000516 xref: EMBL:AB209257 xref: EMBL:AF040253 xref: EMBL:BC024203 xref: EMBL:U56402 xref: EMBL:Y12790 xref: HGNC:HGNC:11469 xref: UniGene:Hs.631604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001345 ! SPT5H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005667 name: SPTBN1_human def: "Spectrin beta chain, brain 1 gene" [UniProtKB:Q01082] synonym: "SPTB2" EXACT [UniProtKB:Q01082] xref: EMBL:AB209748 xref: EMBL:AC092839 xref: EMBL:AC093110 xref: EMBL:AF327441 xref: EMBL:AJ005694 xref: EMBL:AJ238723 xref: EMBL:M96803 xref: EMBL:S65762 xref: HGNC:HGNC:11275 xref: UniGene:Hs.503178 xref: UniGene:Hs.705692 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005604 ! SPTB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005668 name: SPTLC2_human def: "Serine palmitoyltransferase 2 gene" [UniProtKB:O15270] synonym: "KIAA0526" EXACT [UniProtKB:O15270] synonym: "LCB2" EXACT [UniProtKB:O15270] xref: EMBL:AB011098 xref: EMBL:AF111168 xref: EMBL:BC005123 xref: EMBL:U15555 xref: EMBL:Y08686 xref: HGNC:HGNC:11278 xref: UniGene:Hs.435661 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006017 ! SPTC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005669 name: SORBS1_human def: "Sorbin and SH3 domain-containing protein 1 gene" [UniProtKB:Q9BX66] synonym: "KIAA0894" EXACT [UniProtKB:Q9BX66] synonym: "KIAA1296" EXACT [UniProtKB:Q9BX66] synonym: "SH3D5" EXACT [UniProtKB:Q9BX66] xref: EMBL:AB037717 xref: EMBL:AF136380 xref: EMBL:AF136381 xref: EMBL:AF330623 xref: EMBL:AF330624 xref: EMBL:AF356525 xref: EMBL:AF356526 xref: EMBL:AF356527 xref: EMBL:AJ489942 xref: EMBL:AL117472 xref: EMBL:AL158165 xref: EMBL:BC042612 xref: EMBL:U70668 xref: HGNC:HGNC:14565 xref: UniGene:Hs.696027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005641 ! SRBS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005670 name: SRC_human def: "Proto-oncogene tyrosine-protein kinase Src gene" [UniProtKB:P12931] synonym: "SRC1" EXACT [UniProtKB:P12931] xref: EMBL:AL133293 xref: EMBL:BC011566 xref: EMBL:BC051270 xref: EMBL:K03212 xref: EMBL:K03213 xref: EMBL:K03214 xref: EMBL:K03215 xref: EMBL:K03216 xref: EMBL:K03217 xref: EMBL:K03218 xref: EMBL:M16237 xref: EMBL:M16243 xref: EMBL:M16244 xref: EMBL:M16245 xref: EMBL:X02647 xref: EMBL:X03995 xref: EMBL:X03996 xref: EMBL:X03997 xref: EMBL:X03998 xref: EMBL:X03999 xref: EMBL:X04000 xref: HGNC:HGNC:11283 xref: UniGene:Hs.195659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005464 ! SRC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005671 name: SRPK1_human def: "Serine/threonine-protein kinase SRPK1 gene" [UniProtKB:Q96SB4] xref: EMBL:AJ318054 xref: EMBL:BC038292 xref: EMBL:U09564 xref: EMBL:Z99128 xref: HGNC:HGNC:11305 xref: UniGene:Hs.443861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002061 ! SRPK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005672 name: SRPRB_human def: "Signal recognition particle receptor subunit beta gene" [UniProtKB:Q9Y5M8] synonym: "PSEC0230" EXACT [UniProtKB:Q9Y5M8] xref: EMBL:AF141882 xref: EMBL:AK027525 xref: EMBL:AK075531 xref: EMBL:BC065299 xref: HGNC:HGNC:24085 xref: UniGene:Hs.584950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006313 ! SRPRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005673 name: SERTAD1_human def: "SERTA domain-containing protein 1 gene" [UniProtKB:Q9UHV2] synonym: "SEI1" EXACT [UniProtKB:Q9UHV2] xref: EMBL:AF117959 xref: EMBL:AF366402 xref: EMBL:AY130860 xref: EMBL:BC002670 xref: HGNC:HGNC:17932 xref: UniGene:Hs.269898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002202 ! SRTD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005674 name: SSSCA1_human def: "Sjoegren syndrome/scleroderma autoantigen 1 gene" [UniProtKB:O60232] xref: EMBL:AB001740 xref: EMBL:BC014791 xref: HGNC:HGNC:11328 xref: UniGene:Hs.654840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001405 ! SSA27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005675 name: SSR1_human def: "Translocon-associated protein subunit alpha precursor gene" [UniProtKB:P43307] synonym: "PSEC0262" EXACT [UniProtKB:P43307] synonym: "TRAPA" EXACT [UniProtKB:P43307] xref: EMBL:AF156965 xref: EMBL:AK075562 xref: EMBL:AK222762 xref: EMBL:AK222809 xref: EMBL:AK291550 xref: EMBL:AL139095 xref: EMBL:BC007710 xref: EMBL:BT007387 xref: EMBL:CR456961 xref: EMBL:Z12830 xref: HGNC:HGNC:11323 xref: UniGene:Hs.699196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006163 ! SSRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005676 name: SSRP1_human def: "FACT complex subunit SSRP1 gene" [UniProtKB:Q08945] synonym: "FACT80" EXACT [UniProtKB:Q08945] xref: EMBL:BC005116 xref: EMBL:BC091486 xref: EMBL:M86737 xref: HGNC:HGNC:11327 xref: UniGene:Hs.523680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005769 ! SSRP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005677 name: SULT1E1_human def: "Estrogen sulfotransferase gene" [UniProtKB:P49888] synonym: "STE" EXACT [UniProtKB:P49888] xref: EMBL:AY436634 xref: EMBL:BC027956 xref: EMBL:S77383 xref: EMBL:U08098 xref: EMBL:U20515 xref: EMBL:U20516 xref: EMBL:U20517 xref: EMBL:U20518 xref: EMBL:U20519 xref: EMBL:U20520 xref: EMBL:U20521 xref: EMBL:U55764 xref: EMBL:Y11195 xref: HGNC:HGNC:11377 xref: UniGene:Hs.479898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006112 ! ST1E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005678 name: ST5_human def: "Suppression of tumorigenicity 5 gene" [UniProtKB:P78524] synonym: "DENND2B" EXACT [UniProtKB:P78524] synonym: "HTS1" EXACT [UniProtKB:P78524] xref: EMBL:AJ400879 xref: EMBL:BC036655 xref: EMBL:S45936 xref: EMBL:U15131 xref: EMBL:U15779 xref: EMBL:U15780 xref: HGNC:HGNC:11350 xref: UniGene:Hs.117715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006063 ! ST5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005679 name: SUPT7L_human def: "STAGA complex 65 subunit gamma gene" [UniProtKB:O94864] synonym: "KIAA0764" EXACT [UniProtKB:O94864] xref: EMBL:AB018307 xref: EMBL:AC074091 xref: EMBL:AF197954 xref: EMBL:AF224759 xref: EMBL:BC074000 xref: EMBL:CR456983 xref: HGNC:HGNC:30632 xref: UniGene:Hs.6232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006301 ! ST65G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005680 name: STARD13_human def: "StAR-related lipid transfer protein 13 gene" [UniProtKB:Q9Y3M8] synonym: "DLC2" EXACT [UniProtKB:Q9Y3M8] synonym: "GT650" EXACT [UniProtKB:Q9Y3M8] xref: EMBL:AL049801 xref: EMBL:AL139187 xref: EMBL:AL627232 xref: EMBL:AY082589 xref: EMBL:AY082590 xref: EMBL:AY082591 xref: EMBL:AY366448 xref: EMBL:BC046563 xref: EMBL:BX647695 xref: EMBL:Z84483 xref: HGNC:HGNC:19164 xref: UniGene:Hs.507704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002253 ! STA13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005681 name: STAT5A_human def: "Signal transducer and activator of transcription 5A gene" [UniProtKB:P42229] synonym: "STAT5" EXACT [UniProtKB:P42229] xref: EMBL:BC027036 xref: EMBL:L41142 xref: EMBL:U43185 xref: HGNC:HGNC:11366 xref: UniGene:Hs.437058 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001609 ! STA5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005682 name: STAT5B_human def: "Signal transducer and activator of transcription 5B gene" [UniProtKB:P51692] xref: EMBL:AJ412888 xref: EMBL:AJ412889 xref: EMBL:AJ412890 xref: EMBL:AJ412891 xref: EMBL:AJ412892 xref: EMBL:AJ412893 xref: EMBL:AJ412894 xref: EMBL:AJ412895 xref: EMBL:AJ412896 xref: EMBL:AJ412897 xref: EMBL:AJ412898 xref: EMBL:AJ412899 xref: EMBL:BC065227 xref: EMBL:U47686 xref: EMBL:U48730 xref: HGNC:HGNC:11367 xref: UniGene:Hs.632256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001651 ! STA5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005683 name: STAG1_human def: "Cohesin subunit SA-1 gene" [UniProtKB:Q8WVM7] synonym: "SA1" EXACT [UniProtKB:Q8WVM7] xref: EMBL:AC069524 xref: EMBL:AC107425 xref: EMBL:AC128712 xref: EMBL:BC017735 xref: EMBL:Z75330 xref: HGNC:HGNC:11354 xref: UniGene:Hs.412586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002004 ! STAG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005684 name: STAG2_human def: "Cohesin subunit SA-2 gene" [UniProtKB:Q8N3U4] synonym: "SA2" EXACT [UniProtKB:Q8N3U4] xref: EMBL:AL355476 xref: EMBL:AL831939 xref: EMBL:BC001765 xref: EMBL:Z75331 xref: HGNC:HGNC:11355 xref: UniGene:Hs.496710 xref: UniGene:Hs.624663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001962 ! STAG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005685 name: STAG3_human def: "Cohesin subunit SA-3 gene" [UniProtKB:Q9UJ98] xref: EMBL:AJ007798 xref: EMBL:AL833816 xref: HGNC:HGNC:11356 xref: UniGene:Hs.592283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002209 ! STAG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005686 name: STAT1_human def: "Signal transducer and activator of transcription 1-alpha/beta gene" [UniProtKB:P42224] xref: EMBL:AC067945 xref: EMBL:AY366464 xref: EMBL:AY865620 xref: EMBL:BC002704 xref: EMBL:M97935 xref: EMBL:M97936 xref: EMBL:U18662 xref: EMBL:U18663 xref: EMBL:U18664 xref: EMBL:U18665 xref: EMBL:U18666 xref: EMBL:U18667 xref: EMBL:U18668 xref: EMBL:U18669 xref: EMBL:U18670 xref: HGNC:HGNC:11362 xref: UniGene:Hs.642990 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001608 ! STAT1_HUMAN relationship: codes_for CCO:B0023430 ! Q67C41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005687 name: STAT3_human def: "Signal transducer and activator of transcription 3 gene" [UniProtKB:P40763] synonym: "APRF" EXACT [UniProtKB:P40763] xref: EMBL:AF029311 xref: EMBL:AJ012463 xref: EMBL:AY572796 xref: EMBL:BC000627 xref: EMBL:BC014482 xref: EMBL:L29277 xref: HGNC:HGNC:11364 xref: UniGene:Hs.463059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005379 ! STAT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005688 name: STAU1_human def: "Double-stranded RNA-binding protein Staufen homolog 1 gene" [UniProtKB:O95793] synonym: "STAU" EXACT [UniProtKB:O95793] xref: EMBL:AF061938 xref: EMBL:AF061939 xref: EMBL:AF061940 xref: EMBL:AF061941 xref: EMBL:AJ132258 xref: EMBL:AL133174 xref: EMBL:AL136601 xref: EMBL:BC050432 xref: EMBL:BC095397 xref: HGNC:HGNC:11370 xref: UniGene:Hs.596704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005483 ! STAU1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005689 name: STC2_human def: "Stanniocalcin-2 precursor gene" [UniProtKB:O76061] xref: EMBL:AB012664 xref: EMBL:AF031036 xref: EMBL:AF055460 xref: EMBL:AF098462 xref: EMBL:BC000658 xref: EMBL:BC006352 xref: EMBL:BC013958 xref: EMBL:BT019591 xref: HGNC:HGNC:11374 xref: UniGene:Hs.233160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006237 ! STC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005690 name: STEAP3_human def: "Metalloreductase STEAP3 gene" [UniProtKB:Q658P3] synonym: "TSAP6" EXACT [UniProtKB:Q658P3] xref: EMBL:AC016673 xref: EMBL:AC016736 xref: EMBL:AF238864 xref: EMBL:AF262322 xref: EMBL:AF423424 xref: EMBL:AK001691 xref: EMBL:AL833624 xref: EMBL:AY029585 xref: EMBL:AY082673 xref: EMBL:AY214461 xref: EMBL:BC042150 xref: EMBL:BC095421 xref: EMBL:BX538047 xref: HGNC:HGNC:24592 xref: UniGene:Hs.647822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001903 ! STEA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005691 name: STK11_human def: "Serine/threonine-protein kinase 11 gene" [UniProtKB:Q15831] synonym: "LKB1" EXACT [UniProtKB:Q15831] synonym: "PJS" EXACT [UniProtKB:Q15831] xref: EMBL:AF032984 xref: EMBL:AF035625 xref: EMBL:AF055320 xref: EMBL:AF055321 xref: EMBL:AF055322 xref: EMBL:AF055323 xref: EMBL:AF055324 xref: EMBL:AF055325 xref: EMBL:AF055326 xref: EMBL:AF055327 xref: EMBL:BC007981 xref: EMBL:BC019334 xref: EMBL:U63333 xref: HGNC:HGNC:11389 xref: UniGene:Hs.515005 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001814 ! STK11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005692 name: STK19_human def: "Serine/threonine-protein kinase 19 gene" [UniProtKB:P49842] synonym: "G11" EXACT [UniProtKB:P49842] synonym: "RP1" EXACT [UniProtKB:P49842] xref: EMBL:AF019413 xref: EMBL:AL049547 xref: EMBL:AL645922 xref: EMBL:AL662849 xref: EMBL:BX679671 xref: EMBL:CH471081 xref: EMBL:CR753822 xref: EMBL:CR753845 xref: EMBL:CR759782 xref: EMBL:L26260 xref: EMBL:L26261 xref: EMBL:U24578 xref: EMBL:X77386 xref: EMBL:X77474 xref: EMBL:X77489 xref: EMBL:X77490 xref: EMBL:X77491 xref: HGNC:HGNC:11398 xref: UniGene:Hs.654371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005896 ! STK19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005693 name: STK36_human def: "Serine/threonine-protein kinase 36 gene" [UniProtKB:Q9NRP7] synonym: "KIAA1278" EXACT [UniProtKB:Q9NRP7] xref: EMBL:AB033104 xref: EMBL:AF200815 xref: EMBL:AK022692 xref: EMBL:AL133630 xref: EMBL:BC026158 xref: HGNC:HGNC:17209 xref: UniGene:Hs.471404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005375 ! STK36_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005694 name: STK4_human def: "Serine/threonine-protein kinase 4 gene" [UniProtKB:Q13043] synonym: "MST1" EXACT [UniProtKB:Q13043] xref: EMBL:AL109839 xref: EMBL:BC029511 xref: EMBL:BC058916 xref: EMBL:BC093768 xref: EMBL:U18297 xref: EMBL:U60207 xref: EMBL:Z93016 xref: HGNC:HGNC:11408 xref: UniGene:Hs.472838 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005702 ! STK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005695 name: AURKA_human def: "Serine/threonine-protein kinase 6 gene" [UniProtKB:O14965] synonym: "AIK" EXACT [UniProtKB:O14965] synonym: "ARK1" EXACT [UniProtKB:O14965] synonym: "AURA" EXACT [UniProtKB:O14965] synonym: "BTAK" EXACT [UniProtKB:O14965] synonym: "STK15" EXACT [UniProtKB:O14965] synonym: "STK6" EXACT [UniProtKB:O14965] xref: EMBL:AF008551 xref: EMBL:AF011467 xref: EMBL:AF011468 xref: EMBL:AF195942 xref: EMBL:AF195943 xref: EMBL:AF195944 xref: EMBL:AF195945 xref: EMBL:AF195946 xref: EMBL:AF195947 xref: EMBL:AL121914 xref: EMBL:BC001280 xref: EMBL:BC002499 xref: EMBL:BC006423 xref: EMBL:BC027464 xref: EMBL:D84212 xref: HGNC:HGNC:11393 xref: UniGene:Hs.250822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001363 ! STK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005696 name: STMN1_human def: "Stathmin gene" [UniProtKB:P16949] synonym: "LAP18" EXACT [UniProtKB:P16949] synonym: "OP18" EXACT [UniProtKB:P16949] xref: EMBL:AL033528 xref: EMBL:BC082228 xref: EMBL:J04991 xref: EMBL:M31303 xref: EMBL:X53305 xref: EMBL:X94912 xref: EMBL:Z11566 xref: HGNC:HGNC:6510 xref: UniGene:Hs.209983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001528 ! STMN1_HUMAN relationship: codes_for CCO:B0023033 ! A2A2D2_HUMAN relationship: codes_for CCO:B0023035 ! A2A2D0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005697 name: STRAD_human def: "STE20-related adapter protein gene" [UniProtKB:Q7RTN6] synonym: "LYK5" EXACT [UniProtKB:Q7RTN6] xref: EMBL:AF308302 xref: EMBL:AK074771 xref: EMBL:AK075005 xref: EMBL:AY290821 xref: EMBL:BK001542 xref: UniGene:Hs.514402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001932 ! STRAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005698 name: STRN3_human def: "Striatin-3 gene" [UniProtKB:Q13033] synonym: "GS2NA" EXACT [UniProtKB:Q13033] synonym: "SG2NA" EXACT [UniProtKB:Q13033] xref: EMBL:AF243424 xref: EMBL:U17989 xref: HGNC:HGNC:15720 xref: UniGene:Hs.401843 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001737 ! STRN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005699 name: STRN4_human def: "Striatin-4 gene" [UniProtKB:Q9NRL3] synonym: "ZIN" EXACT [UniProtKB:Q9NRL3] xref: EMBL:AF212940 xref: EMBL:BC004910 xref: EMBL:BC034604 xref: HGNC:HGNC:15721 xref: UniGene:Hs.631590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006352 ! STRN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005700 name: STX11_human def: "Syntaxin-11 gene" [UniProtKB:O75558] xref: EMBL:AF038898 xref: EMBL:AF044309 xref: EMBL:AF071504 xref: EMBL:AL135917 xref: EMBL:BC033519 xref: EMBL:CH471051 xref: HGNC:HGNC:11429 xref: UniGene:Hs.118958 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005220 ! STX11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005701 name: STX5_human def: "Syntaxin-5 gene" [UniProtKB:Q13190] synonym: "STX5A" EXACT [UniProtKB:Q13190] xref: EMBL:BC002645 xref: EMBL:BC012137 xref: EMBL:BT019646 xref: EMBL:BT019647 xref: EMBL:BX537426 xref: EMBL:U26648 xref: HGNC:HGNC:11440 xref: UniGene:Hs.654602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006164 ! STX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005702 name: SUFU_human def: "Suppressor of fused homolog gene" [UniProtKB:Q9UMX1] synonym: "UNQ650/PRO1280" EXACT [UniProtKB:Q9UMX1] xref: EMBL:AF144231 xref: EMBL:AF159447 xref: EMBL:AF172319 xref: EMBL:AF175770 xref: EMBL:AF222345 xref: EMBL:AL121928 xref: EMBL:AL137465 xref: EMBL:AL157386 xref: EMBL:AL391121 xref: EMBL:AY081818 xref: EMBL:AY081819 xref: EMBL:AY081820 xref: EMBL:AY081821 xref: EMBL:AY081822 xref: EMBL:AY081823 xref: EMBL:AY081824 xref: EMBL:AY081825 xref: EMBL:AY081826 xref: EMBL:AY081827 xref: EMBL:AY081828 xref: EMBL:AY081829 xref: EMBL:AY358550 xref: EMBL:BC013291 xref: HGNC:HGNC:16466 xref: UniGene:Hs.404089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002232 ! SUFU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005703 name: SUGT1_human def: "Suppressor of G2 allele of SKP1 homolog gene" [UniProtKB:Q9Y2Z0] xref: EMBL:AF132856 xref: EMBL:AJ344097 xref: EMBL:AY271314 xref: EMBL:AY321358 xref: EMBL:BC000911 xref: EMBL:BT009798 xref: HGNC:HGNC:16987 xref: UniGene:Hs.281902 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002252 ! SUGT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005704 name: SUMO1_human def: "Small ubiquitin-related modifier 1 precursor gene" [UniProtKB:P63165] synonym: "OK/SW-cl.43" EXACT [UniProtKB:P63165] synonym: "SMT3C" EXACT [UniProtKB:P63165] synonym: "SMT3H3" EXACT [UniProtKB:P63165] synonym: "UBL1" EXACT [UniProtKB:P63165] xref: EMBL:AB062294 xref: EMBL:AC079354 xref: EMBL:BC006462 xref: EMBL:BC053528 xref: EMBL:BC066306 xref: EMBL:BT006632 xref: EMBL:CR542147 xref: EMBL:CR542156 xref: EMBL:U38784 xref: EMBL:U61397 xref: EMBL:U67122 xref: EMBL:U72722 xref: EMBL:U83117 xref: EMBL:X99586 xref: HGNC:HGNC:12502 xref: UniGene:Hs.81424 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005472 ! SUMO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005705 name: SUPT3H_human def: "Transcription initiation protein SPT3 homolog gene" [UniProtKB:O75486] synonym: "SPT3" EXACT [UniProtKB:O75486] xref: EMBL:AF064804 xref: EMBL:AF069734 xref: EMBL:AF073930 xref: EMBL:AK313874 xref: EMBL:AL096865 xref: EMBL:AL138880 xref: EMBL:AL161905 xref: EMBL:AL360272 xref: EMBL:AL499610 xref: EMBL:BC050384 xref: EMBL:CH471081 xref: HGNC:HGNC:11466 xref: UniGene:Hs.368325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001431 ! SUPT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005706 name: SUV39H1_human def: "Histone-lysine N-methyltransferase SUV39H1 gene" [UniProtKB:O43463] synonym: "KMT1A" EXACT [UniProtKB:O43463] synonym: "SUV39H" EXACT [UniProtKB:O43463] xref: EMBL:AF019968 xref: EMBL:AF196970 xref: EMBL:AK223071 xref: EMBL:BC006238 xref: EMBL:CR541746 xref: HGNC:HGNC:11479 xref: UniGene:Hs.522639 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001391 ! SUV91_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005707 name: SUV39H2_human def: "Histone-lysine N-methyltransferase SUV39H2 gene" [UniProtKB:Q9H5I1] synonym: "KMT1B" EXACT [UniProtKB:Q9H5I1] xref: EMBL:AC069544 xref: EMBL:AK027067 xref: EMBL:AL360083 xref: EMBL:AL834488 xref: EMBL:BC007754 xref: EMBL:BC029360 xref: EMBL:CR457372 xref: HGNC:HGNC:17287 xref: UniGene:Hs.554883 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002139 ! SUV92_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005708 name: SYCE1_human def: "Synaptonemal complex central element protein 1 gene" [UniProtKB:Q8N0S2] synonym: "C10orf94" EXACT [UniProtKB:Q8N0S2] xref: EMBL:AL161645 xref: EMBL:AY027807 xref: EMBL:AY027808 xref: EMBL:AY028079 xref: EMBL:BC034821 xref: HGNC:HGNC:28852 xref: UniGene:Hs.553795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001960 ! SYCE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005709 name: SYCE2_human def: "Synaptonemal complex central element protein 2 gene" [UniProtKB:Q6PIF2] synonym: "CESC1" EXACT [UniProtKB:Q6PIF2] xref: EMBL:AC092069 xref: EMBL:AD000092 xref: EMBL:BC035819 xref: EMBL:CR746484 xref: HGNC:HGNC:27411 xref: UniGene:Hs.655173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001915 ! SYCE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005710 name: SYCP1_human def: "Synaptonemal complex protein 1 gene" [UniProtKB:Q15431] synonym: "SCP1" EXACT [UniProtKB:Q15431] xref: EMBL:AL358372 xref: EMBL:AL645502 xref: EMBL:BC126266 xref: EMBL:CH471122 xref: EMBL:D67035 xref: EMBL:X95654 xref: HGNC:HGNC:11487 xref: UniGene:Hs.112743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001808 ! SYCP1_HUMAN relationship: codes_for CCO:B0001900 ! Q5VXJ5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005711 name: SYCP2_human def: "Synaptonemal complex protein 2 gene" [UniProtKB:Q9BX26] synonym: "SCP2" EXACT [UniProtKB:Q9BX26] xref: EMBL:AL080226 xref: EMBL:AL109928 xref: EMBL:AL158092 xref: EMBL:Y08982 xref: HGNC:HGNC:11490 xref: UniGene:Hs.202676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002106 ! SYCP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005712 name: SYCP3_human def: "Synaptonemal complex protein 3 gene" [UniProtKB:Q8IZU3] synonym: "SCP3" EXACT [UniProtKB:Q8IZU3] xref: EMBL:AF492003 xref: EMBL:AF517774 xref: EMBL:BC062662 xref: HGNC:HGNC:18130 xref: UniGene:Hs.506504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001957 ! SYCP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005714 name: KARS_human def: "Lysyl-tRNA synthetase gene" [UniProtKB:Q15046] synonym: "KIAA0070" EXACT [UniProtKB:Q15046] xref: EMBL:BC004132 xref: EMBL:D31890 xref: EMBL:D32053 xref: HGNC:HGNC:6215 xref: UniGene:Hs.3100 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006279 ! SYK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005715 name: TSC22D4_human def: "TSC22 domain family protein 4 gene" [UniProtKB:Q9Y3Q8] synonym: "TILZ2" EXACT [UniProtKB:Q9Y3Q8] xref: EMBL:AC092849 xref: EMBL:AJ133115 xref: EMBL:AK297702 xref: EMBL:BC001486 xref: EMBL:BC001966 xref: EMBL:BC002972 xref: EMBL:BC010406 xref: EMBL:CH471091 xref: HGNC:HGNC:21696 xref: UniGene:Hs.469798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005176 ! T22D4_HUMAN relationship: codes_for CCO:B0054081 ! A8MWR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005716 name: GTF2F1_human def: "General transcription factor IIF subunit 1 gene" [UniProtKB:P35269] synonym: "RAP74" EXACT [UniProtKB:P35269] xref: EMBL:BC000120 xref: EMBL:BC013007 xref: EMBL:BT007097 xref: EMBL:X64002 xref: EMBL:X64037 xref: HGNC:HGNC:4652 xref: UniGene:Hs.68257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005354 ! T2FA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005717 name: TRAF3IP3_human def: "TRAF3-interacting JNK-activating modulator gene" [UniProtKB:Q9Y228] synonym: "T3JAM" EXACT [UniProtKB:Q9Y228] xref: EMBL:AL022398 xref: EMBL:AL049667 xref: EMBL:BC110302 xref: HGNC:HGNC:30766 xref: UniGene:Hs.147434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006023 ! T3JAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005718 name: TRAF4AF1_human def: "Putative TRAF4-associated factor 1 gene" [UniProtKB:Q9Y448] synonym: "C15orf23" EXACT [UniProtKB:Q9Y448] synonym: "HSD11" EXACT [UniProtKB:Q9Y448] xref: EMBL:AY652615 xref: EMBL:BC004543 xref: EMBL:BC014060 xref: EMBL:BC045739 xref: EMBL:BC064344 xref: EMBL:BC107802 xref: EMBL:BC118559 xref: EMBL:BC118639 xref: EMBL:U81002 xref: HGNC:HGNC:30767 xref: UniGene:Hs.525796 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005561 ! T4AF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005719 name: MAP3K7IP1_human def: "Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 gene" [UniProtKB:Q15750] synonym: "TAB1" EXACT [UniProtKB:Q15750] xref: EMBL:BC050554 xref: EMBL:DQ314876 xref: EMBL:U49928 xref: EMBL:Z83845 xref: HGNC:HGNC:18157 xref: UniGene:Hs.507681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005531 ! TAB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005720 name: MAP3K7IP2_human def: "Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 gene" [UniProtKB:Q9NYJ8] synonym: "KIAA0733" EXACT [UniProtKB:Q9NYJ8] synonym: "TAB2" EXACT [UniProtKB:Q9NYJ8] xref: EMBL:AB018276 xref: EMBL:AF241230 xref: EMBL:AL031133 xref: EMBL:AL117407 xref: EMBL:AL138727 xref: EMBL:AL139103 xref: EMBL:BC035910 xref: EMBL:CR457387 xref: EMBL:DQ314877 xref: HGNC:HGNC:17075 xref: UniGene:Hs.269775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005532 ! TAB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005721 name: TACC1_human def: "Transforming acidic coiled-coil-containing protein 1 gene" [UniProtKB:O75410] synonym: "KIAA1103" EXACT [UniProtKB:O75410] xref: EMBL:AB029026 xref: EMBL:AF049910 xref: EMBL:AY039239 xref: EMBL:AY072874 xref: EMBL:AY072875 xref: EMBL:AY072876 xref: EMBL:AY139007 xref: EMBL:AY177411 xref: EMBL:BC041391 xref: HGNC:HGNC:11522 xref: UniGene:Hs.279245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001425 ! TACC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005722 name: TACC2_human def: "Transforming acidic coiled-coil-containing protein 2 gene" [UniProtKB:O95359] xref: EMBL:AC063960 xref: EMBL:AF095791 xref: EMBL:AF176646 xref: EMBL:AF220152 xref: EMBL:AF528098 xref: EMBL:AF528099 xref: EMBL:AL135793 xref: EMBL:AL713712 xref: EMBL:BC000999 xref: EMBL:BC039311 xref: HGNC:HGNC:11523 xref: UniGene:Hs.501252 xref: UniGene:Hs.699946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006276 ! TACC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005723 name: TADA3L_human def: "Transcriptional adapter 3-like gene" [UniProtKB:O75528] synonym: "ADA3" EXACT [UniProtKB:O75528] xref: EMBL:AF069733 xref: EMBL:AK000228 xref: EMBL:AL117487 xref: EMBL:BC009240 xref: EMBL:BC013433 xref: HGNC:HGNC:19422 xref: UniGene:Hs.386390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001433 ! TAD3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005724 name: TAF10_human def: "Transcription initiation factor TFIID subunit 10 gene" [UniProtKB:Q12962] synonym: "TAF2A" EXACT [UniProtKB:Q12962] synonym: "TAF2H" EXACT [UniProtKB:Q12962] synonym: "TAFII30" EXACT [UniProtKB:Q12962] xref: EMBL:AF498312 xref: EMBL:BC012088 xref: EMBL:U13991 xref: EMBL:U25816 xref: HGNC:HGNC:11543 xref: UniGene:Hs.705378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005937 ! TAF10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005725 name: TAF1L_human def: "Transcription initiation factor TFIID 210 kDa subunit gene" [UniProtKB:Q8IZX4] xref: EMBL:AF390562 xref: HGNC:HGNC:18056 xref: UniGene:Hs.591086 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001959 ! TAF1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005726 name: TAF1_human def: "Transcription initiation factor TFIID subunit 1 gene" [UniProtKB:P21675] synonym: "BA2R" EXACT [UniProtKB:P21675] synonym: "CCG1" EXACT [UniProtKB:P21675] synonym: "CCGS" EXACT [UniProtKB:P21675] synonym: "TAF2A" EXACT [UniProtKB:P21675] xref: EMBL:AB209316 xref: EMBL:AJ549247 xref: EMBL:AJ549248 xref: EMBL:AJ549249 xref: EMBL:AJ549250 xref: EMBL:AJ555148 xref: EMBL:AJ555149 xref: EMBL:AM711894 xref: EMBL:AY623109 xref: EMBL:D90359 xref: EMBL:X07024 xref: HGNC:HGNC:11535 xref: UniGene:Hs.158560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001543 ! TAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005727 name: TAF9_human def: "Transcription initiation factor TFIID subunit 9 gene" [UniProtKB:Q16594] synonym: "TAF2G" EXACT [UniProtKB:Q16594] synonym: "TAFII31" EXACT [UniProtKB:Q16594] xref: EMBL:AY189986 xref: EMBL:BC003400 xref: EMBL:BC033320 xref: EMBL:BT019652 xref: EMBL:U21858 xref: EMBL:U25112 xref: EMBL:U30504 xref: HGNC:HGNC:11542 xref: UniGene:Hs.653163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005938 ! TAF9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005728 name: TAK1L_human def: "TAK1-like protein gene" [UniProtKB:P57077] synonym: "C21orf7" EXACT [UniProtKB:P57077] xref: EMBL:AF269161 xref: EMBL:AF269162 xref: EMBL:AF269163 xref: EMBL:AF269164 xref: EMBL:AL163249 xref: EMBL:AY033900 xref: EMBL:AY171599 xref: EMBL:BC008567 xref: HGNC:HGNC:16457 xref: UniGene:Hs.222802 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005300 ! TAK1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005729 name: TAP1_human def: "Antigen peptide transporter 1 gene" [UniProtKB:Q03518] synonym: "ABCB2" EXACT [UniProtKB:Q03518] synonym: "PSF1" EXACT [UniProtKB:Q03518] synonym: "RING4" EXACT [UniProtKB:Q03518] synonym: "Y3" EXACT [UniProtKB:Q03518] xref: EMBL:AL669918 xref: EMBL:AL671681 xref: EMBL:AL935043 xref: EMBL:BC014081 xref: EMBL:BX927138 xref: EMBL:CH471081 xref: EMBL:CR753889 xref: EMBL:CR762476 xref: EMBL:CR933844 xref: EMBL:L21204 xref: EMBL:L21205 xref: EMBL:L21206 xref: EMBL:L21207 xref: EMBL:L21208 xref: EMBL:S70274 xref: EMBL:X57521 xref: EMBL:X57522 xref: EMBL:X66401 xref: EMBL:X87344 xref: HGNC:HGNC:43 xref: UniGene:Hs.352018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005889 ! TAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005730 name: TUBA1A_human def: "Tubulin alpha-1A chain gene" [UniProtKB:Q71U36] synonym: "TUBA3" EXACT [UniProtKB:Q71U36] xref: EMBL:AF141347 xref: EMBL:BC006468 xref: EMBL:BC050637 xref: EMBL:K00557 xref: EMBL:X01703 xref: HGNC:HGNC:20766 xref: UniGene:Hs.654422 xref: UniGene:Hs.694199 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005772 ! TBA1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005731 name: TUBA1B_human def: "Tubulin alpha-1B chain gene" [UniProtKB:P68363] xref: EMBL:AF081484 xref: EMBL:BC000696 xref: EMBL:BC001128 xref: EMBL:BC006379 xref: EMBL:BC006481 xref: EMBL:BC008659 xref: EMBL:BC009314 xref: EMBL:BC009509 xref: EMBL:BC009512 xref: EMBL:BC009513 xref: EMBL:BC010494 xref: EMBL:BC011572 xref: EMBL:BC015883 xref: EMBL:BC017004 xref: EMBL:BC030820 xref: EMBL:BC071904 xref: EMBL:DQ400107 xref: EMBL:K00558 xref: HGNC:HGNC:18809 xref: UniGene:Hs.524390 xref: UniGene:Hs.705373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024588 ! TBA1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005732 name: TUBA4A_human def: "Tubulin alpha-4A chain gene" [UniProtKB:P68366] synonym: "TUBA1" EXACT [UniProtKB:P68366] xref: EMBL:AY895018 xref: EMBL:BC009238 xref: EMBL:BT006731 xref: EMBL:X06956 xref: HGNC:HGNC:12407 xref: UniGene:Hs.75318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005449 ! TBA4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005733 name: TUBB2A_human def: "Tubulin beta-2A chain gene" [UniProtKB:Q13885] synonym: "TUBB2" EXACT [UniProtKB:Q13885] xref: EMBL:AL031963 xref: EMBL:AY159127 xref: EMBL:BC001194 xref: EMBL:BC018780 xref: EMBL:CR541958 xref: EMBL:X79535 xref: HGNC:HGNC:12412 xref: UniGene:Hs.654543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001769 ! TBB2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005734 name: TUBB2B_human def: "Tubulin beta-2B chain gene" [UniProtKB:Q9BVA1] xref: EMBL:AL445309 xref: EMBL:BC001352 xref: EMBL:BC063610 xref: EMBL:BT019930 xref: EMBL:CR456788 xref: HGNC:HGNC:30829 xref: UniGene:Hs.300701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002101 ! TBB2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005735 name: TUBB3_human def: "Tubulin beta-3 chain gene" [UniProtKB:Q13509] synonym: "TUBB4" EXACT [UniProtKB:Q13509] xref: EMBL:AF427491 xref: EMBL:BC000748 xref: EMBL:BC003021 xref: EMBL:U47634 xref: HGNC:HGNC:20772 xref: UniGene:Hs.511743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001754 ! TBB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005736 name: TUBB4_human def: "Tubulin beta-4 chain gene" [UniProtKB:P04350] synonym: "TUBB5" EXACT [UniProtKB:P04350] xref: EMBL:BC006570 xref: EMBL:BC013683 xref: EMBL:X00734 xref: HGNC:HGNC:20774 xref: UniGene:Hs.110837 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006167 ! TBB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005737 name: TUBB_human def: "Tubulin beta chain gene" [UniProtKB:P07437] synonym: "OK/SW-cl.56" EXACT [UniProtKB:P07437] synonym: "TUBB5" EXACT [UniProtKB:P07437] xref: EMBL:AB062393 xref: EMBL:AB088100 xref: EMBL:AF070561 xref: EMBL:AF070593 xref: EMBL:AF070600 xref: EMBL:AF141349 xref: EMBL:BA000025 xref: EMBL:BC001938 xref: EMBL:BC002347 xref: EMBL:BC005838 xref: EMBL:BC007605 xref: EMBL:BC013374 xref: EMBL:BC019924 xref: EMBL:BC020946 xref: EMBL:BC021909 xref: EMBL:BC070326 xref: EMBL:J00314 xref: HGNC:HGNC:20778 xref: UniGene:Hs.636480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005727 ! TBB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005738 name: TBC1D17_human def: "TBC1 domain family member 17 gene" [UniProtKB:Q9HA65] xref: EMBL:AK022230 xref: EMBL:BC003516 xref: HGNC:HGNC:25699 xref: UniGene:Hs.631587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005279 ! TBC17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005739 name: TUBE1_human def: "Tubulin epsilon chain gene" [UniProtKB:Q9UJT0] synonym: "TUBE" EXACT [UniProtKB:Q9UJT0] xref: EMBL:AF201334 xref: EMBL:BC025405 xref: EMBL:BC031101 xref: HGNC:HGNC:20775 xref: UniGene:Hs.34851 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002211 ! TBE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005740 name: TUBG1_human def: "Tubulin gamma-1 chain gene" [UniProtKB:P23258] synonym: "TUBG" EXACT [UniProtKB:P23258] xref: EMBL:BC000619 xref: EMBL:BT019931 xref: EMBL:M61764 xref: HGNC:HGNC:12417 xref: UniGene:Hs.279669 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001548 ! TBG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005741 name: TBK1_human def: "Serine/threonine-protein kinase TBK1 gene" [UniProtKB:Q9UHD2] synonym: "NAK" EXACT [UniProtKB:Q9UHD2] xref: EMBL:AF174536 xref: EMBL:AF191838 xref: EMBL:AK002192 xref: EMBL:BC034950 xref: HGNC:HGNC:11584 xref: UniGene:Hs.505874 xref: UniGene:Hs.607889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005533 ! TBK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005742 name: TBL1XR1_human def: "F-box-like/WD repeat-containing protein TBL1XR1 gene" [UniProtKB:Q9BZK7] synonym: "IRA1" EXACT [UniProtKB:Q9BZK7] synonym: "TBLR1" EXACT [UniProtKB:Q9BZK7] xref: EMBL:AF268193 xref: EMBL:AF314544 xref: EMBL:AK022956 xref: EMBL:BC060320 xref: EMBL:BC113421 xref: HGNC:HGNC:29529 xref: UniGene:Hs.581171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006041 ! TBL1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005743 name: TBL3_human def: "WD repeat-containing protein SAZD gene" [UniProtKB:Q12788] synonym: "SAZD" EXACT [UniProtKB:Q12788] xref: EMBL:BC010231 xref: EMBL:BC014007 xref: EMBL:CH471112 xref: EMBL:U02609 xref: HGNC:HGNC:11587 xref: UniGene:Hs.513267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005261 ! Q96A78_HUMAN relationship: codes_for CCO:B0006309 ! TBL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005744 name: TBP_human def: "TATA-box-binding protein gene" [UniProtKB:P20226] synonym: "GTF2D1" EXACT [UniProtKB:P20226] synonym: "TF2D" EXACT [UniProtKB:P20226] synonym: "TFIID" EXACT [UniProtKB:P20226] xref: EMBL:AL031259 xref: EMBL:BC109054 xref: EMBL:M34960 xref: EMBL:M55654 xref: EMBL:X54993 xref: HGNC:HGNC:11588 xref: UniGene:Hs.590872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005481 ! TBP_HUMAN relationship: codes_for CCO:B0032981 ! Q32MN6_HUMAN relationship: codes_for CCO:B0057200 ! Q7Z6S5_HUMAN relationship: codes_for CCO:B0057201 ! Q7Z6S6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005745 name: TBRG1_human def: "Transforming growth factor beta regulator 1 gene" [UniProtKB:Q3YBR2] synonym: "NIAM" EXACT [UniProtKB:Q3YBR2] xref: EMBL:AK027527 xref: EMBL:AK074140 xref: EMBL:AK222936 xref: EMBL:AL713631 xref: EMBL:AL831881 xref: EMBL:AY696294 xref: EMBL:BC109269 xref: EMBL:DQ144542 xref: HGNC:HGNC:29551 xref: UniGene:Hs.436410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001832 ! TBRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005746 name: TBRG4_human def: "Protein TBRG4 gene" [UniProtKB:Q969Z0] synonym: "CPR2" EXACT [UniProtKB:Q969Z0] synonym: "FASTKD4" EXACT [UniProtKB:Q969Z0] synonym: "KIAA0948" EXACT [UniProtKB:Q969Z0] xref: EMBL:AB023165 xref: EMBL:AF011792 xref: EMBL:AK222943 xref: EMBL:AL833840 xref: EMBL:BC002732 xref: EMBL:BC014918 xref: EMBL:BC017235 xref: HGNC:HGNC:17443 xref: UniGene:Hs.231411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002030 ! TBRG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005747 name: TBX3_human def: "T-box transcription factor TBX3 gene" [UniProtKB:O15119] xref: EMBL:AF002228 xref: EMBL:AF140240 xref: EMBL:AF170708 xref: EMBL:AF216750 xref: EMBL:BC025258 xref: HGNC:HGNC:11602 xref: UniGene:Hs.129895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001365 ! TBX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005748 name: TCEA2_human def: "Transcription elongation factor A protein 2 gene" [UniProtKB:Q15560] xref: EMBL:AL590548 xref: EMBL:BC018896 xref: EMBL:BC050623 xref: EMBL:CH471077 xref: EMBL:D50495 xref: EMBL:U86749 xref: HGNC:HGNC:11614 xref: UniGene:Hs.505004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006303 ! TCEA2_HUMAN relationship: codes_for CCO:B0056464 ! Q5JRI7_HUMAN relationship: codes_for CCO:B0057262 ! Q86VL0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005749 name: TCP10_human def: "T-complex protein 10A homolog gene" [UniProtKB:Q12799] synonym: "TCP10A" EXACT [UniProtKB:Q12799] xref: EMBL:AL021331 xref: EMBL:AL592444 xref: EMBL:U03399 xref: HGNC:HGNC:11656 xref: UniGene:Hs.119929 xref: UniGene:Hs.351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005617 ! TCP10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005750 name: CCT2_human def: "T-complex protein 1 subunit beta gene" [UniProtKB:P78371] synonym: "99D8.1" EXACT [UniProtKB:P78371] synonym: "CCTB" EXACT [UniProtKB:P78371] xref: EMBL:AF026166 xref: EMBL:AF026293 xref: EMBL:BC113514 xref: EMBL:BC113516 xref: EMBL:BT019966 xref: EMBL:CR457071 xref: EMBL:U91327 xref: HGNC:HGNC:1615 xref: UniGene:Hs.189772 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001700 ! TCPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005751 name: CCT4_human def: "T-complex protein 1 subunit delta gene" [UniProtKB:P50991] synonym: "CCTD" EXACT [UniProtKB:P50991] synonym: "SRB" EXACT [UniProtKB:P50991] xref: EMBL:AC107081 xref: EMBL:AF026291 xref: EMBL:BC014676 xref: EMBL:BC106933 xref: EMBL:BC106934 xref: EMBL:U38846 xref: HGNC:HGNC:1617 xref: UniGene:Hs.421509 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001648 ! TCPD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005752 name: CCT5_human def: "T-complex protein 1 subunit epsilon gene" [UniProtKB:P48643] synonym: "CCTE" EXACT [UniProtKB:P48643] synonym: "KIAA0098" EXACT [UniProtKB:P48643] xref: EMBL:BC006543 xref: EMBL:BC035499 xref: EMBL:D43950 xref: HGNC:HGNC:1618 xref: UniGene:Hs.1600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005291 ! TCPE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005753 name: CCT3_human def: "T-complex protein 1 subunit gamma gene" [UniProtKB:P49368] synonym: "CCTG" EXACT [UniProtKB:P49368] synonym: "TRIC5" EXACT [UniProtKB:P49368] xref: EMBL:AL589685 xref: EMBL:AL833197 xref: EMBL:BC006501 xref: EMBL:BC008019 xref: EMBL:U17104 xref: EMBL:X74801 xref: HGNC:HGNC:1616 xref: UniGene:Hs.491494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005253 ! TCPG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005754 name: CCT7_human def: "T-complex protein 1 subunit eta gene" [UniProtKB:Q99832] synonym: "CCTH" EXACT [UniProtKB:Q99832] synonym: "NIP7-1" EXACT [UniProtKB:Q99832] xref: EMBL:AC010913 xref: EMBL:AF026292 xref: EMBL:BC019296 xref: EMBL:BC088351 xref: EMBL:CR536511 xref: EMBL:U83843 xref: HGNC:HGNC:1622 xref: UniGene:Hs.368149 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002089 ! TCPH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005755 name: TCERG1_human def: "Transcription elongation regulator 1 gene" [UniProtKB:O14776] synonym: "CA150" EXACT [UniProtKB:O14776] synonym: "TAF2S" EXACT [UniProtKB:O14776] xref: EMBL:AB209910 xref: EMBL:AF017789 xref: EMBL:BC111727 xref: HGNC:HGNC:15630 xref: UniGene:Hs.443465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005396 ! TCRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005756 name: TDGF1_human def: "Teratocarcinoma-derived growth factor 1 precursor gene" [UniProtKB:P13385] synonym: "CRIPTO" EXACT [UniProtKB:P13385] xref: EMBL:M96955 xref: EMBL:X14253 xref: HGNC:HGNC:11701 xref: UniGene:Hs.385870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006244 ! TDGF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005757 name: TDRD7_human def: "Tudor domain-containing protein 7 gene" [UniProtKB:Q8NHU6] synonym: "PCTAIRE2BP" EXACT [UniProtKB:Q8NHU6] xref: EMBL:AB025254 xref: EMBL:AL122110 xref: EMBL:AL449464 xref: EMBL:AL512590 xref: EMBL:BC028694 xref: HGNC:HGNC:30831 xref: UniGene:Hs.193842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005496 ! TDRD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005758 name: TERF2IP_human def: "Telomeric repeat-binding factor 2-interacting protein 1 gene" [UniProtKB:Q9NYB0] synonym: "PP8000" EXACT [UniProtKB:Q9NYB0] synonym: "RAP1" EXACT [UniProtKB:Q9NYB0] xref: EMBL:AF262988 xref: EMBL:AF289599 xref: EMBL:AK000669 xref: EMBL:BC004465 xref: EMBL:BC005841 xref: EMBL:BC022428 xref: EMBL:BC078171 xref: HGNC:HGNC:19246 xref: UniGene:Hs.301419 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005505 ! TE2IP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005759 name: TCAP_human def: "Telethonin gene" [UniProtKB:O15273] xref: EMBL:AJ000491 xref: EMBL:AJ010063 xref: EMBL:AJ011098 xref: EMBL:BC012628 xref: EMBL:BC013330 xref: HGNC:HGNC:11610 xref: UniGene:Hs.514146 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005387 ! TELT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005760 name: TERF1_human def: "Telomeric repeat-binding factor 1 gene" [UniProtKB:P54274] synonym: "PIN2" EXACT [UniProtKB:P54274] synonym: "TRBF1" EXACT [UniProtKB:P54274] synonym: "TRF" EXACT [UniProtKB:P54274] synonym: "TRF1" EXACT [UniProtKB:P54274] xref: EMBL:AC022893 xref: EMBL:AF003001 xref: EMBL:EU088287 xref: EMBL:U40705 xref: EMBL:U70992 xref: EMBL:U70993 xref: EMBL:U74382 xref: EMBL:X93511 xref: HGNC:HGNC:11728 xref: UniGene:Hs.442707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001667 ! TERF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005761 name: TERF2_human def: "Telomeric repeat-binding factor 2 gene" [UniProtKB:Q15554] synonym: "TRBF2" EXACT [UniProtKB:Q15554] synonym: "TRF2" EXACT [UniProtKB:Q15554] xref: EMBL:AF002999 xref: EMBL:BC024890 xref: EMBL:U95970 xref: EMBL:X93512 xref: HGNC:HGNC:11729 xref: UniGene:Hs.63335 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001810 ! TERF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005762 name: TEX11_human def: "Testis-expressed sequence 11 protein gene" [UniProtKB:Q8IYF3] xref: EMBL:AF285594 xref: EMBL:AK057391 xref: EMBL:AK057523 xref: EMBL:AL139109 xref: EMBL:AL627071 xref: EMBL:AL627390 xref: EMBL:BC036016 xref: HGNC:HGNC:11733 xref: UniGene:Hs.121776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005187 ! TEX11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005763 name: GTF2H1_human def: "General transcription factor IIH subunit 1 gene" [UniProtKB:P32780] synonym: "BTF2" EXACT [UniProtKB:P32780] xref: EMBL:AJ131959 xref: EMBL:AK027003 xref: EMBL:AY163770 xref: EMBL:BC000365 xref: EMBL:BC004452 xref: EMBL:M95809 xref: HGNC:HGNC:4655 xref: UniGene:Hs.577202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001585 ! TF2H1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005764 name: GTF3C1_human def: "General transcription factor 3C polypeptide 1 gene" [UniProtKB:Q12789] xref: EMBL:AC002303 xref: EMBL:AC002551 xref: EMBL:AC025275 xref: EMBL:BC044857 xref: EMBL:BC137229 xref: EMBL:U02619 xref: EMBL:U06485 xref: HGNC:HGNC:4664 xref: UniGene:Hs.371718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006211 ! TF3C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005765 name: RELA_human def: "Transcription factor p65 gene" [UniProtKB:Q04206] synonym: "NFKB3" EXACT [UniProtKB:Q04206] xref: EMBL:AY455868 xref: EMBL:BC033522 xref: EMBL:BC110830 xref: EMBL:L19067 xref: EMBL:M62399 xref: EMBL:Z22948 xref: EMBL:Z22949 xref: EMBL:Z22950 xref: EMBL:Z22951 xref: EMBL:Z22953 xref: HGNC:HGNC:9955 xref: UniGene:Hs.502875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005865 ! TF65_HUMAN relationship: codes_for CCO:B0056227 ! Q2TAM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005766 name: TCF7L1_human def: "Transcription factor 7-like 1 gene" [UniProtKB:Q9HCS4] synonym: "TCF3" EXACT [UniProtKB:Q9HCS4] xref: EMBL:AB031046 xref: EMBL:AC011236 xref: EMBL:AC093162 xref: EMBL:BC058894 xref: EMBL:X62870 xref: HGNC:HGNC:11640 xref: UniGene:Hs.516297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002146 ! TF7L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005767 name: TCF7L2_human def: "Transcription factor 7-like 2 gene" [UniProtKB:Q9NQB0] synonym: "TCF4" EXACT [UniProtKB:Q9NQB0] xref: EMBL:AB034691 xref: EMBL:AJ270770 xref: EMBL:AJ270771 xref: EMBL:AJ270772 xref: EMBL:AJ270773 xref: EMBL:AJ270774 xref: EMBL:AJ270775 xref: EMBL:AJ270776 xref: EMBL:AJ270777 xref: EMBL:AJ270778 xref: EMBL:AL135792 xref: EMBL:AL158212 xref: EMBL:AL445486 xref: EMBL:AL451084 xref: EMBL:BC032656 xref: EMBL:Y11306 xref: HGNC:HGNC:11641 xref: UniGene:Hs.593995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002152 ! TF7L2_HUMAN relationship: codes_for CCO:B0056472 ! Q5JRY3_HUMAN relationship: codes_for CCO:B0056473 ! Q5JRY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005768 name: TFDP1_human def: "Transcription factor Dp-1 gene" [UniProtKB:Q14186] synonym: "DP1" EXACT [UniProtKB:Q14186] xref: EMBL:AF550129 xref: EMBL:AL442125 xref: EMBL:BC011685 xref: EMBL:CH471085 xref: EMBL:L23959 xref: HGNC:HGNC:11749 xref: UniGene:Hs.79353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001776 ! TFDP1_HUMAN relationship: codes_for CCO:B0001854 ! Q5JSB5_HUMAN relationship: codes_for CCO:B0001855 ! Q5JSB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005769 name: TFDP2_human def: "Transcription factor Dp-2 gene" [UniProtKB:Q14188] synonym: "DP2" EXACT [UniProtKB:Q14188] xref: EMBL:AY509596 xref: EMBL:BC021113 xref: EMBL:L40386 xref: EMBL:U18422 xref: EMBL:U35117 xref: EMBL:U75488 xref: HGNC:HGNC:11751 xref: UniGene:Hs.379018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001777 ! TFDP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005770 name: TFDP3_human def: "Transcription factor Dp family member 3 gene" [UniProtKB:Q5H9I0] synonym: "HCA661" EXACT [UniProtKB:Q5H9I0] xref: EMBL:AF219119 xref: EMBL:BC074762 xref: EMBL:BC117336 xref: EMBL:BC126361 xref: EMBL:CH471107 xref: EMBL:Z77249 xref: HGNC:HGNC:24603 xref: UniGene:Hs.142908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001849 ! TFDP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005771 name: TCF3_human def: "Transcription factor E2-alpha gene" [UniProtKB:P15923] synonym: "E2A" EXACT [UniProtKB:P15923] synonym: "ITF1" EXACT [UniProtKB:P15923] xref: EMBL:AC005321 xref: EMBL:AC006274 xref: EMBL:BC110580 xref: EMBL:M24404 xref: EMBL:M24405 xref: EMBL:M31222 xref: EMBL:M31522 xref: EMBL:M31523 xref: EMBL:M65214 xref: EMBL:X52078 xref: HGNC:HGNC:11633 xref: UniGene:Hs.371282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006057 ! TFE2_HUMAN relationship: codes_for CCO:B0056230 ! Q2TB39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005772 name: TGFA_human def: "Protransforming growth factor alpha precursor gene" [UniProtKB:P01135] xref: EMBL:AF123238 xref: EMBL:AF123239 xref: EMBL:AF123240 xref: EMBL:AF123241 xref: EMBL:AF123242 xref: EMBL:AF123243 xref: EMBL:K03222 xref: EMBL:M22440 xref: EMBL:M31172 xref: EMBL:X70340 xref: HGNC:HGNC:11765 xref: UniGene:Hs.170009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005870 ! TGFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005773 name: TGFB1_human def: "Transforming growth factor beta-1 precursor gene" [UniProtKB:P01137] synonym: "TGFB" EXACT [UniProtKB:P01137] xref: EMBL:BC000125 xref: EMBL:BC001180 xref: EMBL:BC022242 xref: EMBL:BT007245 xref: EMBL:M38449 xref: EMBL:X02812 xref: EMBL:X05839 xref: EMBL:X05840 xref: EMBL:X05843 xref: EMBL:X05844 xref: EMBL:X05849 xref: EMBL:X05850 xref: HGNC:HGNC:11766 xref: UniGene:Hs.645227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001471 ! TGFB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005774 name: TGFB2_human def: "Transforming growth factor beta-2 precursor gene" [UniProtKB:P61812] xref: EMBL:AY438979 xref: EMBL:BC096235 xref: EMBL:BC099635 xref: EMBL:M19154 xref: EMBL:M87843 xref: EMBL:Y00083 xref: HGNC:HGNC:11768 xref: UniGene:Hs.133379 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001687 ! TGFB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005775 name: TGFB3_human def: "Transforming growth factor beta-3 precursor gene" [UniProtKB:P10600] xref: EMBL:AF107885 xref: EMBL:AY140241 xref: EMBL:AY208161 xref: EMBL:J03241 xref: EMBL:X14149 xref: EMBL:X14885 xref: EMBL:X14886 xref: EMBL:X14887 xref: EMBL:X14888 xref: EMBL:X14889 xref: EMBL:X14890 xref: EMBL:X14891 xref: HGNC:HGNC:11769 xref: UniGene:Hs.592317 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001507 ! TGFB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005776 name: TGFBR2_human def: "TGF-beta receptor type-2 precursor gene" [UniProtKB:P37173] xref: EMBL:AY675319 xref: EMBL:D28131 xref: EMBL:D50683 xref: EMBL:M85079 xref: EMBL:U52240 xref: EMBL:U52241 xref: EMBL:U52242 xref: EMBL:U52244 xref: EMBL:U52245 xref: EMBL:U52246 xref: EMBL:U69146 xref: EMBL:U69147 xref: EMBL:U69148 xref: EMBL:U69149 xref: EMBL:U69150 xref: EMBL:U69151 xref: EMBL:U69152 xref: HGNC:HGNC:11773 xref: UniGene:Hs.604277 xref: UniGene:Hs.82028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005542 ! TGFR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005777 name: TGIF1_human def: "Homeobox protein TGIF1 gene" [UniProtKB:Q15583] synonym: "TGIF" EXACT [UniProtKB:Q15583] xref: EMBL:AF179900 xref: EMBL:AK291112 xref: EMBL:AP001025 xref: EMBL:BC000814 xref: EMBL:BC031268 xref: EMBL:CH471113 xref: EMBL:CR450333 xref: EMBL:X89750 xref: HGNC:HGNC:11776 xref: UniGene:Hs.373550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006246 ! TGIF1_HUMAN relationship: codes_for CCO:B0053801 ! A6NE42_HUMAN relationship: codes_for CCO:B0053899 ! A6NLU7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005778 name: THAP8_human def: "THAP domain-containing protein 8 gene" [UniProtKB:Q8NA92] xref: EMBL:AK057453 xref: EMBL:AK093048 xref: EMBL:BC072416 xref: HGNC:HGNC:23191 xref: UniGene:Hs.350209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006304 ! THAP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005779 name: TXN_human def: "Thioredoxin gene" [UniProtKB:P10599] synonym: "TRDX" EXACT [UniProtKB:P10599] synonym: "TRX" EXACT [UniProtKB:P10599] synonym: "TRX1" EXACT [UniProtKB:P10599] xref: EMBL:AF276919 xref: EMBL:AF313911 xref: EMBL:AF548001 xref: EMBL:AK289508 xref: EMBL:AL158158 xref: EMBL:AY004872 xref: EMBL:BC003377 xref: EMBL:BC054866 xref: EMBL:CH471105 xref: EMBL:CR407665 xref: EMBL:J04026 xref: EMBL:X54539 xref: EMBL:X54540 xref: EMBL:X54541 xref: EMBL:X77584 xref: HGNC:HGNC:12435 xref: UniGene:Hs.435136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005808 ! THIO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005780 name: F2_human def: "Prothrombin precursor gene" [UniProtKB:P00734] xref: EMBL:AF478696 xref: EMBL:M17262 xref: EMBL:V00595 xref: HGNC:HGNC:3535 xref: UniGene:Hs.655207 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001464 ! THRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005781 name: TRIM28_human def: "Transcription intermediary factor 1-beta gene" [UniProtKB:Q13263] synonym: "KAP1" EXACT [UniProtKB:Q13263] synonym: "RNF96" EXACT [UniProtKB:Q13263] synonym: "TIF1B" EXACT [UniProtKB:Q13263] xref: EMBL:BC004978 xref: EMBL:BC007390 xref: EMBL:BC052986 xref: EMBL:U31657 xref: EMBL:U78773 xref: EMBL:U95040 xref: EMBL:X97548 xref: HGNC:HGNC:16384 xref: UniGene:Hs.467408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005585 ! TIF1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005782 name: TIMELESS_human def: "Protein timeless homolog gene" [UniProtKB:Q9UNS1] synonym: "TIM" EXACT [UniProtKB:Q9UNS1] synonym: "TIM1" EXACT [UniProtKB:Q9UNS1] synonym: "TIMELESS1" EXACT [UniProtKB:Q9UNS1] xref: EMBL:AB015597 xref: EMBL:AF098162 xref: EMBL:BC039842 xref: EMBL:BC050557 xref: HGNC:HGNC:11813 xref: UniGene:Hs.118631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002235 ! TIM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005783 name: TINF2_human def: "TERF1-interacting nuclear factor 2 gene" [UniProtKB:Q9BSI4] synonym: "TIN2" EXACT [UniProtKB:Q9BSI4] xref: EMBL:AF195512 xref: EMBL:AK023166 xref: EMBL:BC005030 xref: EMBL:BC019343 xref: HGNC:HGNC:11824 xref: UniGene:Hs.496191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006245 ! TINF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005784 name: HTATIP_human def: "Histone acetyltransferase HTATIP gene" [UniProtKB:Q92993] synonym: "TIP60" EXACT [UniProtKB:Q92993] xref: EMBL:AY214165 xref: EMBL:BC000166 xref: EMBL:BC064912 xref: EMBL:BC117167 xref: EMBL:U40989 xref: EMBL:U67734 xref: EMBL:U74667 xref: HGNC:HGNC:5275 xref: UniGene:Hs.528299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005351 ! TIP60_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005785 name: TIPIN_human def: "TIMELESS-interacting protein gene" [UniProtKB:Q9BVW5] xref: EMBL:AK000523 xref: EMBL:BC000870 xref: EMBL:BK001386 xref: EMBL:CH471082 xref: HGNC:HGNC:30750 xref: UniGene:Hs.572318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002104 ! TIPIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005786 name: TTN_human def: "Titin gene" [UniProtKB:Q8WZ42] xref: EMBL:AC009948 xref: EMBL:AF058332 xref: EMBL:AF525413 xref: EMBL:AJ277892 xref: EMBL:AL713647 xref: EMBL:BC013396 xref: EMBL:BC058824 xref: EMBL:BC070170 xref: EMBL:BC107797 xref: EMBL:DQ248309 xref: EMBL:X64697 xref: EMBL:X64698 xref: EMBL:X64699 xref: EMBL:X69490 xref: EMBL:X83270 xref: EMBL:X90568 xref: EMBL:X90569 xref: EMBL:X98114 xref: EMBL:X98115 xref: HGNC:HGNC:12403 xref: UniGene:Hs.654592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002013 ! TITIN_HUMAN relationship: codes_for CCO:B0019050 ! A6NKB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005787 name: TAC3_human def: "Tachykinin-3 precursor gene" [UniProtKB:Q9UHF0] synonym: "NKNB" EXACT [UniProtKB:Q9UHF0] synonym: "UNQ585/PRO1155" EXACT [UniProtKB:Q9UHF0] xref: EMBL:AF186112 xref: EMBL:AF216586 xref: EMBL:AF537113 xref: EMBL:AF537114 xref: EMBL:AF537115 xref: EMBL:AF537116 xref: EMBL:AF537117 xref: EMBL:AF537118 xref: EMBL:AF537119 xref: EMBL:AF537120 xref: EMBL:AF537121 xref: EMBL:AY358679 xref: EMBL:BC032145 xref: EMBL:CR457193 xref: HGNC:HGNC:11521 xref: UniGene:Hs.9730 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006242 ! TKNK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005788 name: TLE1_human def: "Transducin-like enhancer protein 1 gene" [UniProtKB:Q04724] xref: EMBL:AL353682 xref: EMBL:AL365190 xref: EMBL:BC010100 xref: EMBL:BC015747 xref: EMBL:M99435 xref: HGNC:HGNC:11837 xref: UniGene:Hs.197320 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005511 ! TLE1_HUMAN relationship: codes_for CCO:B0016909 ! A6NFH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005789 name: TLE2_human def: "Transducin-like enhancer protein 2 gene" [UniProtKB:Q04725] xref: EMBL:AC007766 xref: EMBL:AC011549 xref: EMBL:BC017364 xref: EMBL:M99436 xref: HGNC:HGNC:11838 xref: UniGene:Hs.332173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005657 ! TLE2_HUMAN relationship: codes_for CCO:B0016921 ! A6NFJ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005790 name: TLE3_human def: "Transducin-like enhancer protein 3 gene" [UniProtKB:Q04726] synonym: "KIAA1547" EXACT [UniProtKB:Q04726] xref: EMBL:AB046767 xref: EMBL:BC015729 xref: EMBL:BC041831 xref: EMBL:M99438 xref: HGNC:HGNC:11839 xref: UniGene:Hs.287362 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005690 ! TLE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005791 name: TLK1_human def: "Serine/threonine-protein kinase tousled-like 1 gene" [UniProtKB:Q9UKI8] synonym: "KIAA0137" EXACT [UniProtKB:Q9UKI8] xref: EMBL:AB004885 xref: EMBL:AF162666 xref: EMBL:AF246219 xref: EMBL:BC032657 xref: EMBL:D50927 xref: HGNC:HGNC:11841 xref: UniGene:Hs.655640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002220 ! TLK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005792 name: TLK2_human def: "Serine/threonine-protein kinase tousled-like 2 gene" [UniProtKB:Q86UE8] xref: EMBL:AB004884 xref: EMBL:AF162667 xref: EMBL:BC044925 xref: HGNC:HGNC:11842 xref: UniGene:Hs.445078 xref: UniGene:Hs.633264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001939 ! TLK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005793 name: TMPRSS11A_human def: "Transmembrane protease, serine 11A gene" [UniProtKB:Q6ZMR5] synonym: "ECRG1" EXACT [UniProtKB:Q6ZMR5] synonym: "HATL1" EXACT [UniProtKB:Q6ZMR5] synonym: "HESP" EXACT [UniProtKB:Q6ZMR5] xref: EMBL:AF071882 xref: EMBL:AK131518 xref: EMBL:AY498712 xref: EMBL:BC111796 xref: EMBL:BN000133 xref: HGNC:HGNC:27954 xref: UniGene:Hs.450110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001922 ! TM11A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005795 name: TOM1L1_human def: "TOM1-like protein 1 gene" [UniProtKB:O75674] synonym: "SRCASM" EXACT [UniProtKB:O75674] xref: EMBL:AJ010071 xref: EMBL:AK223125 xref: EMBL:AK315039 xref: EMBL:CH471109 xref: HGNC:HGNC:11983 xref: UniGene:Hs.153504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006203 ! TM1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005796 name: TMF1_human def: "TATA element modulatory factor gene" [UniProtKB:P82094] xref: EMBL:L01042 xref: HGNC:HGNC:11870 xref: UniGene:Hs.267632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005984 ! TMF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005797 name: TNFSF15_human def: "Tumor necrosis factor ligand superfamily member 15 gene" [UniProtKB:O95150] synonym: "TL1" EXACT [UniProtKB:O95150] synonym: "VEGI" EXACT [UniProtKB:O95150] xref: EMBL:AF039390 xref: EMBL:AF520785 xref: EMBL:AK291642 xref: EMBL:AL390240 xref: EMBL:AY434464 xref: EMBL:BC069435 xref: EMBL:BC074940 xref: EMBL:BC074941 xref: EMBL:BC104462 xref: EMBL:BC104463 xref: EMBL:CH471090 xref: HGNC:HGNC:11931 xref: UniGene:Hs.241382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001448 ! TNF15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005798 name: TNF_human def: "Tumor necrosis factor precursor gene" [UniProtKB:P01375] synonym: "TNFA" EXACT [UniProtKB:P01375] synonym: "TNFSF2" EXACT [UniProtKB:P01375] xref: EMBL:AB088112 xref: EMBL:AF043342 xref: EMBL:AF098751 xref: EMBL:AF129756 xref: EMBL:AY066019 xref: EMBL:AY214167 xref: EMBL:BA000025 xref: EMBL:BC028148 xref: EMBL:M10988 xref: EMBL:M16441 xref: EMBL:M26331 xref: EMBL:X01394 xref: EMBL:X02910 xref: EMBL:Y14768 xref: EMBL:Z15026 xref: HGNC:HGNC:11892 xref: UniGene:Hs.241570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001474 ! TNFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005799 name: LTA_human def: "Lymphotoxin-alpha precursor gene" [UniProtKB:P01374] synonym: "TNFB" EXACT [UniProtKB:P01374] synonym: "TNFSF1" EXACT [UniProtKB:P01374] xref: EMBL:A06316 xref: EMBL:AF129756 xref: EMBL:AY070490 xref: EMBL:AY216498 xref: EMBL:BA000025 xref: EMBL:BC034729 xref: EMBL:D00102 xref: EMBL:D12614 xref: EMBL:M16441 xref: EMBL:M55913 xref: EMBL:X01393 xref: EMBL:X02911 xref: EMBL:Y14768 xref: EMBL:Z15026 xref: HGNC:HGNC:6709 xref: UniGene:Hs.36 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001473 ! TNFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005800 name: TNIK_human def: "TRAF2 and NCK-interacting protein kinase gene" [UniProtKB:Q9UKE5] synonym: "KIAA0551" EXACT [UniProtKB:Q9UKE5] xref: EMBL:AB011123 xref: EMBL:AF172264 xref: EMBL:AF172265 xref: EMBL:AF172266 xref: EMBL:AF172267 xref: EMBL:AF172268 xref: EMBL:AF172269 xref: EMBL:AF172270 xref: EMBL:AF172271 xref: EMBL:BC019081 xref: HGNC:HGNC:30765 xref: UniGene:Hs.34024 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005603 ! TNIK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005801 name: TNPO1_human def: "Transportin-1 gene" [UniProtKB:Q92973] synonym: "KPNB2" EXACT [UniProtKB:Q92973] synonym: "MIP1" EXACT [UniProtKB:Q92973] synonym: "TRN" EXACT [UniProtKB:Q92973] xref: EMBL:BC040340 xref: EMBL:U70322 xref: EMBL:U72069 xref: EMBL:U72395 xref: HGNC:HGNC:6401 xref: UniGene:Hs.482497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005663 ! TNPO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005802 name: TNFRSF14_human def: "Tumor necrosis factor receptor superfamily member 14 precursor gene" [UniProtKB:Q92956] synonym: "HVEA" EXACT [UniProtKB:Q92956] synonym: "HVEM" EXACT [UniProtKB:Q92956] synonym: "UNQ329/PRO509" EXACT [UniProtKB:Q92956] xref: EMBL:AF153978 xref: EMBL:AF373877 xref: EMBL:AF373878 xref: EMBL:AY358879 xref: EMBL:AY466111 xref: EMBL:BC002794 xref: EMBL:CR456909 xref: EMBL:U70321 xref: EMBL:U81232 xref: HGNC:HGNC:11912 xref: UniGene:Hs.512898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005707 ! TNR14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005803 name: TNFRSF1A_human def: "Tumor necrosis factor receptor superfamily member 1A precursor gene" [UniProtKB:P19438] synonym: "TNFAR" EXACT [UniProtKB:P19438] synonym: "TNFR1" EXACT [UniProtKB:P19438] xref: EMBL:A21522 xref: EMBL:AY131997 xref: EMBL:BC010140 xref: EMBL:M33294 xref: EMBL:M58286 xref: EMBL:M60275 xref: EMBL:M63121 xref: EMBL:M75864 xref: EMBL:M75865 xref: EMBL:M75866 xref: EMBL:X55313 xref: HGNC:HGNC:11916 xref: UniGene:Hs.279594 xref: UniGene:Hs.705365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005534 ! TNR1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005804 name: TNFRSF1B_human def: "Tumor necrosis factor receptor superfamily member 1B precursor gene" [UniProtKB:P20333] synonym: "TNFBR" EXACT [UniProtKB:P20333] synonym: "TNFR2" EXACT [UniProtKB:P20333] xref: EMBL:AB030950 xref: EMBL:AL031276 xref: EMBL:AL357835 xref: EMBL:AY148473 xref: EMBL:AY264804 xref: EMBL:AY342040 xref: EMBL:BC052977 xref: EMBL:BT019927 xref: EMBL:M32315 xref: EMBL:M35857 xref: EMBL:M55994 xref: EMBL:S63368 xref: EMBL:U52156 xref: EMBL:U52157 xref: EMBL:U52158 xref: EMBL:U52159 xref: EMBL:U52160 xref: EMBL:U52161 xref: EMBL:U52162 xref: EMBL:U52163 xref: EMBL:U52164 xref: EMBL:U52165 xref: HGNC:HGNC:11917 xref: UniGene:Hs.256278 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005535 ! TNR1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005805 name: FAS_human def: "Tumor necrosis factor receptor superfamily member 6 precursor gene" [UniProtKB:P25445] synonym: "APT1" EXACT [UniProtKB:P25445] synonym: "FAS1" EXACT [UniProtKB:P25445] synonym: "TNFRSF6" EXACT [UniProtKB:P25445] xref: EMBL:AL157394 xref: EMBL:AY450925 xref: EMBL:BC012479 xref: EMBL:M67454 xref: EMBL:X63717 xref: EMBL:X83490 xref: EMBL:X83491 xref: EMBL:X83492 xref: EMBL:X83493 xref: EMBL:X89101 xref: EMBL:Z47993 xref: EMBL:Z47994 xref: EMBL:Z47995 xref: EMBL:Z70519 xref: EMBL:Z70520 xref: HGNC:HGNC:11920 xref: UniGene:Hs.244139 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005479 ! TNR6_HUMAN relationship: codes_for CCO:B0033174 ! Q5T9P3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005806 name: TNFRSF8_human def: "Tumor necrosis factor receptor superfamily member 8 precursor gene" [UniProtKB:P28908] synonym: "CD30" EXACT [UniProtKB:P28908] synonym: "D1S166E" EXACT [UniProtKB:P28908] xref: EMBL:AJ289159 xref: EMBL:AY498860 xref: EMBL:D86042 xref: EMBL:M83554 xref: EMBL:S75768 xref: HGNC:HGNC:11923 xref: UniGene:Hs.1314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006010 ! TNR8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005807 name: TOB2_human def: "Protein Tob2 gene" [UniProtKB:Q14106] synonym: "KIAA1663" EXACT [UniProtKB:Q14106] synonym: "TOB4" EXACT [UniProtKB:Q14106] synonym: "TROB2" EXACT [UniProtKB:Q14106] xref: EMBL:AB035207 xref: EMBL:AB051450 xref: EMBL:AL008582 xref: EMBL:BC038957 xref: EMBL:CR456594 xref: EMBL:D64109 xref: HGNC:HGNC:11980 xref: UniGene:Hs.474978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001774 ! TOB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005808 name: TOLLIP_human def: "Toll-interacting protein gene" [UniProtKB:Q9H0E2] xref: EMBL:AJ242972 xref: EMBL:AK022871 xref: EMBL:AL136835 xref: EMBL:BC004420 xref: EMBL:BC012057 xref: EMBL:BC018272 xref: HGNC:HGNC:16476 xref: UniGene:Hs.368527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005273 ! TOLIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005809 name: TOMM20_human def: "Mitochondrial import receptor subunit TOM20 homolog gene" [UniProtKB:Q15388] synonym: "KIAA0016" EXACT [UniProtKB:Q15388] xref: EMBL:AF126958 xref: EMBL:AF126959 xref: EMBL:AF126960 xref: EMBL:AF126961 xref: EMBL:AF126962 xref: EMBL:AK289810 xref: EMBL:AL732292 xref: EMBL:BC000882 xref: EMBL:BC066335 xref: EMBL:BC071994 xref: EMBL:BC100286 xref: EMBL:BC107851 xref: EMBL:CH471098 xref: EMBL:CR456718 xref: EMBL:D13641 xref: HGNC:HGNC:20947 xref: UniGene:Hs.533192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006116 ! TOM20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005810 name: TOP1_human def: "DNA topoisomerase 1 gene" [UniProtKB:P11387] xref: EMBL:AL022394 xref: EMBL:AL035652 xref: EMBL:J03250 xref: EMBL:M27913 xref: EMBL:M60688 xref: EMBL:M60689 xref: EMBL:M60690 xref: EMBL:M60691 xref: EMBL:M60692 xref: EMBL:M60693 xref: EMBL:M60694 xref: EMBL:M60695 xref: EMBL:M60696 xref: EMBL:M60697 xref: EMBL:M60698 xref: EMBL:M60699 xref: EMBL:M60700 xref: EMBL:M60701 xref: EMBL:M60702 xref: EMBL:M60703 xref: EMBL:M60704 xref: EMBL:M60705 xref: EMBL:M60706 xref: EMBL:U07804 xref: EMBL:U07806 xref: EMBL:X16479 xref: EMBL:X52601 xref: HGNC:HGNC:11986 xref: UniGene:Hs.472737 xref: UniGene:Hs.592136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005587 ! TOP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005811 name: TOP2A_human def: "DNA topoisomerase 2-alpha gene" [UniProtKB:P11388] synonym: "TOP2" EXACT [UniProtKB:P11388] xref: EMBL:AC080112 xref: EMBL:AF064590 xref: EMBL:AF069522 xref: EMBL:AF071738 xref: EMBL:AF071739 xref: EMBL:AF071740 xref: EMBL:AF071741 xref: EMBL:AF071742 xref: EMBL:AF071743 xref: EMBL:AF071744 xref: EMBL:AF071745 xref: EMBL:AF071746 xref: EMBL:AF071747 xref: EMBL:AF285157 xref: EMBL:AF285158 xref: EMBL:AF285159 xref: EMBL:AJ011741 xref: EMBL:AJ011742 xref: EMBL:AJ011743 xref: EMBL:AJ011744 xref: EMBL:AJ011745 xref: EMBL:AJ011746 xref: EMBL:AJ011747 xref: EMBL:AJ011748 xref: EMBL:AJ011749 xref: EMBL:AJ011750 xref: EMBL:AJ011751 xref: EMBL:AJ011752 xref: EMBL:AJ011753 xref: EMBL:AJ011754 xref: EMBL:AJ011755 xref: EMBL:AJ011756 xref: EMBL:AJ011757 xref: EMBL:AJ011758 xref: EMBL:J04088 xref: HGNC:HGNC:11989 xref: UniGene:Hs.156346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005803 ! TOP2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005812 name: TOP3A_human def: "DNA topoisomerase 3-alpha gene" [UniProtKB:Q13472] synonym: "TOP3" EXACT [UniProtKB:Q13472] xref: EMBL:BC051748 xref: EMBL:U43431 xref: HGNC:HGNC:11992 xref: UniGene:Hs.592115 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001753 ! TOP3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005813 name: PBK_human def: "Lymphokine-activated killer T-cell-originated protein kinase gene" [UniProtKB:Q96KB5] synonym: "TOPK" EXACT [UniProtKB:Q96KB5] xref: EMBL:AB027249 xref: EMBL:AB027250 xref: EMBL:AF189722 xref: EMBL:AF237709 xref: EMBL:AK027291 xref: EMBL:BC015191 xref: HGNC:HGNC:18282 xref: UniGene:Hs.104741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002045 ! TOPK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005814 name: PTP4A1_human def: "Protein tyrosine phosphatase type IVA 1 gene" [UniProtKB:Q93096] synonym: "PRL1" EXACT [UniProtKB:Q93096] synonym: "PTPCAAX1" EXACT [UniProtKB:Q93096] xref: EMBL:AF051160 xref: EMBL:AL135905 xref: EMBL:BC023975 xref: EMBL:BC045571 xref: EMBL:CR749458 xref: EMBL:U48296 xref: EMBL:U69701 xref: HGNC:HGNC:9634 xref: UniGene:Hs.227777 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002029 ! TP4A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005815 name: TP53BP1_human def: "Tumor suppressor p53-binding protein 1 gene" [UniProtKB:Q12888] xref: EMBL:AB210025 xref: EMBL:AF078776 xref: EMBL:AY904026 xref: EMBL:BC112161 xref: EMBL:BX537418 xref: EMBL:U09477 xref: HGNC:HGNC:11999 xref: UniGene:Hs.440968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005412 ! TP53B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005816 name: TPD52_human def: "Tumor protein D52 gene" [UniProtKB:P55327] xref: EMBL:AC009686 xref: EMBL:AF202897 xref: EMBL:AK313135 xref: EMBL:BC018117 xref: EMBL:BT019444 xref: EMBL:BX640835 xref: EMBL:CH471068 xref: EMBL:CR542034 xref: EMBL:CR542064 xref: EMBL:S82081 xref: EMBL:U18914 xref: HGNC:HGNC:12005 xref: UniGene:Hs.368433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005373 ! TPD52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005817 name: TPD52L1_human def: "Tumor protein D53 gene" [UniProtKB:Q16890] xref: EMBL:AF004427 xref: EMBL:U44427 xref: EMBL:U44428 xref: HGNC:HGNC:12006 xref: UniGene:Hs.591347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001825 ! TPD53_HUMAN relationship: codes_for CCO:B0005643 ! O43397_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005818 name: TPD52L3_human def: "Tumor protein D55 gene" [UniProtKB:Q96J77] xref: EMBL:AK057479 xref: EMBL:AL133480 xref: EMBL:AY032877 xref: EMBL:BC017589 xref: EMBL:BC033792 xref: EMBL:BC042113 xref: HGNC:HGNC:23382 xref: UniGene:Hs.351815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005918 ! TPD55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005819 name: TPX2_human def: "Targeting protein for Xklp2 gene" [UniProtKB:Q9ULW0] synonym: "C20orf1" EXACT [UniProtKB:Q9ULW0] synonym: "C20orf2" EXACT [UniProtKB:Q9ULW0] synonym: "DIL2" EXACT [UniProtKB:Q9ULW0] synonym: "HCA519" EXACT [UniProtKB:Q9ULW0] xref: EMBL:AB024704 xref: EMBL:AB027467 xref: EMBL:AF098158 xref: EMBL:AF146731 xref: EMBL:AF244547 xref: EMBL:AL117534 xref: EMBL:AL160175 xref: EMBL:BC004136 xref: EMBL:BC020207 xref: HGNC:HGNC:1249 xref: UniGene:Hs.244580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002227 ! TPX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005820 name: AD-001_human def: "TRM112-like protein gene" [UniProtKB:Q9UI30] synonym: "HSPC152" EXACT [UniProtKB:Q9UI30] synonym: "HSPC170" EXACT [UniProtKB:Q9UI30] xref: EMBL:AF110774 xref: EMBL:AF161501 xref: EMBL:AF229068 xref: EMBL:BC017172 xref: EMBL:BC029482 xref: EMBL:BC105294 xref: UniGene:Hs.333579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005568 ! TR112_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005821 name: TRADD_human def: "Tumor necrosis factor receptor type 1-associated DEATH domain protein gene" [UniProtKB:Q15628] xref: EMBL:AJ311614 xref: EMBL:AJ311615 xref: EMBL:AJ311616 xref: EMBL:AY575851 xref: EMBL:AY995114 xref: EMBL:BC004491 xref: EMBL:BT006934 xref: EMBL:L41690 xref: HGNC:HGNC:12030 xref: UniGene:Hs.460996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005672 ! TRADD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005822 name: TRAF1_human def: "TNF receptor-associated factor 1 gene" [UniProtKB:Q13077] synonym: "EBI6" EXACT [UniProtKB:Q13077] xref: EMBL:AK090468 xref: EMBL:BC024145 xref: EMBL:BT019408 xref: EMBL:U19261 xref: HGNC:HGNC:12031 xref: UniGene:Hs.531251 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005992 ! TRAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005823 name: TRAF2_human def: "TNF receptor-associated factor 2 gene" [UniProtKB:Q12933] synonym: "TRAP3" EXACT [UniProtKB:Q12933] xref: EMBL:AK054686 xref: EMBL:AL355987 xref: EMBL:AL449425 xref: EMBL:AY623660 xref: EMBL:BC032410 xref: EMBL:BC033810 xref: EMBL:BC043492 xref: EMBL:BC064662 xref: EMBL:U12597 xref: HGNC:HGNC:12032 xref: UniGene:Hs.522506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005170 ! TRAF2_HUMAN relationship: codes_for CCO:B0054258 ! B1AMX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005824 name: TRAF6_human def: "TNF receptor-associated factor 6 gene" [UniProtKB:Q9Y4K3] synonym: "RNF85" EXACT [UniProtKB:Q9Y4K3] xref: EMBL:AY228337 xref: EMBL:BC031052 xref: EMBL:U78798 xref: HGNC:HGNC:12036 xref: UniGene:Hs.591983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005536 ! TRAF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005825 name: THBD_human def: "Thrombomodulin precursor gene" [UniProtKB:P07204] synonym: "THRM" EXACT [UniProtKB:P07204] xref: EMBL:AF495471 xref: EMBL:AL049651 xref: EMBL:BC035602 xref: EMBL:BC053357 xref: EMBL:D00210 xref: EMBL:J02973 xref: EMBL:M16552 xref: EMBL:X05495 xref: HGNC:HGNC:11784 xref: UniGene:Hs.2030 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005618 ! TRBM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005826 name: TRDMT1_human def: "tRNA (cytosine-5-)-methyltransferase gene" [UniProtKB:O14717] synonym: "DNMT2" EXACT [UniProtKB:O14717] xref: EMBL:AC067747 xref: EMBL:AF012128 xref: EMBL:AF045888 xref: EMBL:AF329940 xref: EMBL:AF329941 xref: EMBL:AF329942 xref: EMBL:AF329943 xref: EMBL:AF329944 xref: EMBL:AJ223333 xref: EMBL:AL133415 xref: EMBL:EF444974 xref: HGNC:HGNC:2977 xref: UniGene:Hs.351665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006138 ! TRDMT_HUMAN relationship: codes_for CCO:B0054194 ! B0YJ06_HUMAN relationship: codes_for CCO:B0056496 ! Q5JVT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005827 name: TRIM13_human def: "Tripartite motif-containing protein 13 gene" [UniProtKB:O60858] synonym: "LEU5" EXACT [UniProtKB:O60858] synonym: "RFP2" EXACT [UniProtKB:O60858] synonym: "RNF77" EXACT [UniProtKB:O60858] xref: EMBL:AF220127 xref: EMBL:AF220128 xref: EMBL:AF241849 xref: EMBL:AF241850 xref: EMBL:AF279660 xref: EMBL:AJ224819 xref: EMBL:AL137060 xref: EMBL:AY191002 xref: EMBL:AY455758 xref: EMBL:BC003579 xref: EMBL:BC063407 xref: HGNC:HGNC:9976 xref: UniGene:Hs.436922 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001416 ! TRI13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005828 name: TRIM27_human def: "Zinc finger protein RFP gene" [UniProtKB:P14373] synonym: "RFP" EXACT [UniProtKB:P14373] synonym: "RNF76" EXACT [UniProtKB:P14373] xref: EMBL:AF230393 xref: EMBL:AF230394 xref: EMBL:AL662859 xref: EMBL:AL662871 xref: EMBL:BC013580 xref: EMBL:BC066924 xref: EMBL:BX000360 xref: EMBL:BX537153 xref: EMBL:J03407 xref: EMBL:Z84474 xref: EMBL:Z84476 xref: HGNC:HGNC:9975 xref: UniGene:Hs.440382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005981 ! TRI27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005829 name: TRIM29_human def: "Tripartite motif-containing protein 29 gene" [UniProtKB:Q14134] synonym: "ATDC" EXACT [UniProtKB:Q14134] xref: EMBL:AF230388 xref: EMBL:AF230389 xref: EMBL:BC017352 xref: EMBL:L24203 xref: HGNC:HGNC:17274 xref: UniGene:Hs.504115 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005204 ! TRI29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005830 name: TRIM37_human def: "Tripartite motif-containing protein 37 gene" [UniProtKB:O94972] synonym: "KIAA0898" EXACT [UniProtKB:O94972] synonym: "MUL" EXACT [UniProtKB:O94972] synonym: "POB1" EXACT [UniProtKB:O94972] xref: EMBL:AB020705 xref: EMBL:AF213365 xref: EMBL:BC036012 xref: EMBL:BX537955 xref: HGNC:HGNC:7523 xref: UniGene:Hs.579079 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005249 ! TRI37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005831 name: TRIAP1_human def: "TP53-regulated inhibitor of apoptosis 1 gene" [UniProtKB:O43715] synonym: "15E1.1" EXACT [UniProtKB:O43715] synonym: "HSPC132" EXACT [UniProtKB:O43715] xref: EMBL:AF161481 xref: EMBL:AL021546 xref: EMBL:BC002638 xref: EMBL:BC055313 xref: EMBL:U75688 xref: HGNC:HGNC:26937 xref: UniGene:Hs.69499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001398 ! TRIA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005832 name: TRIB1_human def: "Tribbles homolog 1 gene" [UniProtKB:Q96RU8] synonym: "C8FW" EXACT [UniProtKB:Q96RU8] synonym: "GIG2" EXACT [UniProtKB:Q96RU8] synonym: "TRB1" EXACT [UniProtKB:Q96RU8] xref: EMBL:AF205437 xref: EMBL:AF250310 xref: EMBL:AJ000480 xref: EMBL:AL832388 xref: EMBL:BC063292 xref: HGNC:HGNC:16891 xref: UniGene:Hs.444947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006002 ! TRIB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005833 name: TRIB3_human def: "Tribbles homolog 3 gene" [UniProtKB:Q96RU7] synonym: "C20orf97" EXACT [UniProtKB:Q96RU7] synonym: "NIPK" EXACT [UniProtKB:Q96RU7] synonym: "SKIP3" EXACT [UniProtKB:Q96RU7] synonym: "TRB3" EXACT [UniProtKB:Q96RU7] xref: EMBL:AF250311 xref: EMBL:AJ697936 xref: EMBL:AK026945 xref: EMBL:AK222837 xref: EMBL:AL034548 xref: EMBL:AY247738 xref: EMBL:BC019363 xref: EMBL:BC027484 xref: EMBL:CR457366 xref: HGNC:HGNC:16228 xref: UniGene:Hs.516826 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005477 ! TRIB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005834 name: MID2_human def: "Midline-2 gene" [UniProtKB:Q9UJV3] synonym: "FXY2" EXACT [UniProtKB:Q9UJV3] synonym: "RNF60" EXACT [UniProtKB:Q9UJV3] synonym: "TRIM1" EXACT [UniProtKB:Q9UJV3] xref: EMBL:AF196481 xref: EMBL:AL034399 xref: EMBL:AL109946 xref: EMBL:BC017707 xref: EMBL:BT006663 xref: EMBL:Y18880 xref: HGNC:HGNC:7096 xref: UniGene:Hs.12256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005969 ! TRIM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005835 name: TRIP6_human def: "Thyroid receptor-interacting protein 6 gene" [UniProtKB:Q15654] synonym: "OIP1" EXACT [UniProtKB:Q15654] xref: EMBL:AF000974 xref: EMBL:AF093834 xref: EMBL:AF093835 xref: EMBL:AF093836 xref: EMBL:AF312032 xref: EMBL:AJ001902 xref: EMBL:BC002680 xref: EMBL:BC004249 xref: EMBL:BC004999 xref: EMBL:BC021540 xref: EMBL:BC028985 xref: EMBL:L40374 xref: HGNC:HGNC:12311 xref: UniGene:Hs.534360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005985 ! TRIP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005836 name: TRIP13_human def: "Thyroid receptor-interacting protein 13 gene" [UniProtKB:Q15645] xref: EMBL:BC000404 xref: EMBL:BC019294 xref: EMBL:CR456744 xref: EMBL:L40384 xref: EMBL:U96131 xref: HGNC:HGNC:12307 xref: UniGene:Hs.436187 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006283 ! TRP13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005837 name: TRRAP_human def: "Transformation/transcription domain-associated protein gene" [UniProtKB:Q9Y4A5] synonym: "PAF400" EXACT [UniProtKB:Q9Y4A5] xref: EMBL:AC004893 xref: EMBL:AC004991 xref: EMBL:AF076974 xref: EMBL:AF110377 xref: HGNC:HGNC:12347 xref: UniGene:Hs.203952 xref: UniGene:Hs.657548 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005350 ! TRRAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005838 name: TSG101_human def: "Tumor susceptibility gene 101 protein gene" [UniProtKB:Q99816] xref: EMBL:BC002487 xref: EMBL:U82130 xref: HGNC:HGNC:15971 xref: UniGene:Hs.523512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005283 ! TS101_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005839 name: TSC1_human def: "Hamartin gene" [UniProtKB:Q92574] synonym: "KIAA0243" EXACT [UniProtKB:Q92574] synonym: "TSC" EXACT [UniProtKB:Q92574] xref: EMBL:AC002096 xref: EMBL:AF013168 xref: EMBL:AF234185 xref: EMBL:D87683 xref: HGNC:HGNC:12362 xref: UniGene:Hs.370854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002014 ! TSC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005840 name: TSC2_human def: "Tuberin gene" [UniProtKB:P49815] synonym: "TSC4" EXACT [UniProtKB:P49815] xref: EMBL:AB014460 xref: EMBL:AC005600 xref: EMBL:BC025364 xref: EMBL:BC046929 xref: EMBL:L48517 xref: EMBL:L48518 xref: EMBL:L48519 xref: EMBL:L48521 xref: EMBL:L48522 xref: EMBL:L48523 xref: EMBL:L48524 xref: EMBL:L48525 xref: EMBL:L48526 xref: EMBL:L48527 xref: EMBL:L48528 xref: EMBL:L48529 xref: EMBL:L48530 xref: EMBL:L48531 xref: EMBL:L48532 xref: EMBL:L48533 xref: EMBL:L48534 xref: EMBL:L48535 xref: EMBL:L48536 xref: EMBL:L48537 xref: EMBL:L48538 xref: EMBL:L48539 xref: EMBL:L48540 xref: EMBL:L48541 xref: EMBL:L48542 xref: EMBL:L48543 xref: EMBL:L48544 xref: EMBL:L48545 xref: EMBL:L48546 xref: EMBL:X75621 xref: HGNC:HGNC:12363 xref: UniGene:Hs.90303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001637 ! TSC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005841 name: TSPYL2_human def: "Testis-specific Y-encoded-like protein 2 gene" [UniProtKB:Q9H2G4] synonym: "CDA1" EXACT [UniProtKB:Q9H2G4] synonym: "DENTT" EXACT [UniProtKB:Q9H2G4] synonym: "HRIHFB2216" EXACT [UniProtKB:Q9H2G4] synonym: "TSPX" EXACT [UniProtKB:Q9H2G4] xref: EMBL:AB015345 xref: EMBL:AF254794 xref: EMBL:AF273046 xref: EMBL:AL713652 xref: EMBL:AY040871 xref: EMBL:BC001566 xref: EMBL:BC024270 xref: EMBL:BX322635 xref: HGNC:HGNC:24358 xref: UniGene:Hs.136164 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002128 ! TSYL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005842 name: TTK_human def: "Dual specificity protein kinase TTK gene" [UniProtKB:P33981] synonym: "MPS1L1" EXACT [UniProtKB:P33981] xref: EMBL:AL133475 xref: EMBL:BC000633 xref: EMBL:BC032858 xref: EMBL:CH471051 xref: EMBL:M86699 xref: EMBL:X70500 xref: HGNC:HGNC:12401 xref: UniGene:Hs.169840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001587 ! TTK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005843 name: TTLL5_human def: "Tubulin polyglutamylase TTLL5 gene" [UniProtKB:Q6EMB2] synonym: "KIAA0998" EXACT [UniProtKB:Q6EMB2] synonym: "STAMP" EXACT [UniProtKB:Q6EMB2] xref: EMBL:AB023215 xref: EMBL:AC007182 xref: EMBL:AC009399 xref: EMBL:AF107885 xref: EMBL:AY237126 xref: HGNC:HGNC:19963 xref: UniGene:Hs.532626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006333 ! TTLL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005844 name: TUSC2_human def: "Tumor suppressor candidate 2 gene" [UniProtKB:O75896] synonym: "FUS1" EXACT [UniProtKB:O75896] synonym: "LGCC" EXACT [UniProtKB:O75896] synonym: "PDAP2" EXACT [UniProtKB:O75896] xref: EMBL:AF055479 xref: EMBL:BC023976 xref: HGNC:HGNC:17034 xref: UniGene:Hs.517981 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001438 ! TUSC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005845 name: TUSC4_human def: "Tumor suppressor candidate 4 gene" [UniProtKB:Q8WTW4] synonym: "NPRL2" EXACT [UniProtKB:Q8WTW4] xref: EMBL:AC002481 xref: EMBL:AF040707 xref: EMBL:AF040708 xref: EMBL:BC021984 xref: EMBL:BC056861 xref: HGNC:HGNC:24969 xref: UniGene:Hs.437083 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002000 ! TUSC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005846 name: TXNDC11_human def: "Thioredoxin domain-containing protein 11 gene" [UniProtKB:Q6PKC3] synonym: "EFP1" EXACT [UniProtKB:Q6PKC3] xref: EMBL:AF131780 xref: EMBL:AK027464 xref: EMBL:AK027646 xref: EMBL:AK074534 xref: EMBL:BC002856 xref: EMBL:BC013727 xref: EMBL:BC018635 xref: EMBL:CR457152 xref: HGNC:HGNC:28030 xref: UniGene:Hs.313847 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005993 ! TXD11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005847 name: TXNL4A_human def: "Thioredoxin-like protein 4A gene" [UniProtKB:P83876] synonym: "DIM1" EXACT [UniProtKB:P83876] synonym: "TXNL4" EXACT [UniProtKB:P83876] xref: EMBL:AF023611 xref: EMBL:AF023612 xref: EMBL:AF146373 xref: EMBL:BC001046 xref: EMBL:BC019272 xref: EMBL:CH471117 xref: HGNC:HGNC:30551 xref: UniGene:Hs.465498 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001361 ! O14835_HUMAN relationship: codes_for CCO:B0001702 ! TXN4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005848 name: TXNL4B_human def: "Thioredoxin-like protein 4B gene" [UniProtKB:Q9NX01] synonym: "DIM2" EXACT [UniProtKB:Q9NX01] synonym: "DLP" EXACT [UniProtKB:Q9NX01] xref: EMBL:AK000518 xref: EMBL:AY566808 xref: EMBL:BC009646 xref: EMBL:CR457240 xref: HGNC:HGNC:26041 xref: UniGene:Hs.134406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002172 ! TXN4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005849 name: TXNIP_human def: "Thioredoxin-interacting protein gene" [UniProtKB:Q9H3M7] synonym: "VDUP1" EXACT [UniProtKB:Q9H3M7] xref: EMBL:AB051901 xref: EMBL:AF333001 xref: EMBL:AL138842 xref: EMBL:AL160282 xref: EMBL:AY594328 xref: EMBL:BC093702 xref: EMBL:BC093704 xref: EMBL:S73591 xref: HGNC:HGNC:16952 xref: UniGene:Hs.533977 xref: UniGene:Hs.702728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002133 ! TXNIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005850 name: TMSB4X_human def: "Thymosin beta-4 gene" [UniProtKB:P62328] synonym: "TB4X" EXACT [UniProtKB:P62328] synonym: "THYB4" EXACT [UniProtKB:P62328] synonym: "TMSB4" EXACT [UniProtKB:P62328] xref: EMBL:AJ295158 xref: EMBL:BT007090 xref: EMBL:M17733 xref: EMBL:X02493 xref: HGNC:HGNC:11881 xref: UniGene:Hs.522584 xref: UniGene:Hs.699565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006115 ! TYB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005851 name: YY1_human def: "Transcriptional repressor protein YY1 gene" [UniProtKB:P25490] synonym: "INO80S" EXACT [UniProtKB:P25490] xref: EMBL:BC037308 xref: EMBL:BC065366 xref: EMBL:M76541 xref: EMBL:M77698 xref: EMBL:Z14077 xref: HGNC:HGNC:12856 xref: UniGene:Hs.388927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006011 ! TYY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005852 name: BAT1_human def: "Spliceosome RNA helicase BAT1 gene" [UniProtKB:Q13838] synonym: "UAP56" EXACT [UniProtKB:Q13838] xref: EMBL:AB088115 xref: EMBL:AB103621 xref: EMBL:AB202112 xref: EMBL:AF029061 xref: EMBL:AF029062 xref: EMBL:AK222912 xref: EMBL:AL662801 xref: EMBL:AL662847 xref: EMBL:BA000025 xref: EMBL:BC000361 xref: EMBL:BC013006 xref: EMBL:BT009909 xref: EMBL:BX001040 xref: EMBL:BX248516 xref: EMBL:BX927320 xref: EMBL:CH471081 xref: EMBL:CR753820 xref: EMBL:CR753864 xref: EMBL:Z37166 xref: HGNC:HGNC:13917 xref: UniGene:Hs.254042 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005899 ! UAP56_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005853 name: CDC34_human def: "Ubiquitin-conjugating enzyme E2 R1 gene" [UniProtKB:P49427] synonym: "UBE2R1" EXACT [UniProtKB:P49427] xref: EMBL:AY650399 xref: EMBL:BC009850 xref: EMBL:BC018143 xref: EMBL:BC023979 xref: EMBL:BT006659 xref: EMBL:L22005 xref: HGNC:HGNC:1734 xref: UniGene:Hs.514997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001628 ! UB2R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005854 name: UBE2V1_human def: "Ubiquitin-conjugating enzyme E2 variant 1 gene" [UniProtKB:Q13404] synonym: "CROC1" EXACT [UniProtKB:Q13404] synonym: "P/OKcl.19" EXACT [UniProtKB:Q13404] synonym: "UBE2V" EXACT [UniProtKB:Q13404] synonym: "UEV1" EXACT [UniProtKB:Q13404] xref: EMBL:AL034423 xref: EMBL:AY008273 xref: EMBL:BC000468 xref: EMBL:BC008944 xref: EMBL:BT007382 xref: EMBL:U39360 xref: EMBL:U39361 xref: EMBL:U49278 xref: EMBL:U97279 xref: EMBL:U97280 xref: EMBL:U97281 xref: HGNC:HGNC:12494 xref: UniGene:Hs.420529 xref: UniGene:Hs.702293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001752 ! UB2V1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005855 name: UBE2V2_human def: "Ubiquitin-conjugating enzyme E2 variant 2 gene" [UniProtKB:Q15819] synonym: "MMS2" EXACT [UniProtKB:Q15819] synonym: "UEV2" EXACT [UniProtKB:Q15819] xref: EMBL:AF049140 xref: EMBL:BC007051 xref: EMBL:BC016332 xref: EMBL:BC016710 xref: EMBL:BC028673 xref: EMBL:BC062418 xref: EMBL:BT006744 xref: EMBL:CR407628 xref: EMBL:U62136 xref: EMBL:X98091 xref: HGNC:HGNC:12495 xref: UniGene:Hs.491695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001813 ! UB2V2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005857 name: UBE2M_human def: "NEDD8-conjugating enzyme Ubc12 gene" [UniProtKB:P61081] synonym: "UBC12" EXACT [UniProtKB:P61081] xref: EMBL:AB012191 xref: EMBL:AF075599 xref: EMBL:BC058924 xref: EMBL:BT006754 xref: HGNC:HGNC:12491 xref: UniGene:Hs.406068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005329 ! UBC12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005858 name: UBE2I_human def: "SUMO-conjugating enzyme UBC9 gene" [UniProtKB:P63279] synonym: "UBC9" EXACT [UniProtKB:P63279] synonym: "UBCE9" EXACT [UniProtKB:P63279] xref: EMBL:AB208988 xref: EMBL:AE006466 xref: EMBL:AJ002385 xref: EMBL:AL031714 xref: EMBL:BC000427 xref: EMBL:BC004429 xref: EMBL:BC051289 xref: EMBL:BT006932 xref: EMBL:D45050 xref: EMBL:U29092 xref: EMBL:U31882 xref: EMBL:U31933 xref: EMBL:U38785 xref: EMBL:U45328 xref: EMBL:U66818 xref: EMBL:U66867 xref: EMBL:X96427 xref: HGNC:HGNC:12485 xref: UniGene:Hs.302903 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001696 ! UBC9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005859 name: UBLCP1_human def: "Ubiquitin-like domain-containing CTD phosphatase 1 gene" [UniProtKB:Q8WVY7] xref: EMBL:AK057996 xref: EMBL:AY444562 xref: EMBL:BC013425 xref: HGNC:HGNC:28110 xref: UniGene:Hs.591733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005278 ! UBCP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005860 name: UBE2C_human def: "Ubiquitin-conjugating enzyme E2 C gene" [UniProtKB:O00762] synonym: "UBCH10" EXACT [UniProtKB:O00762] xref: EMBL:AL050348 xref: EMBL:BC007656 xref: EMBL:BC016292 xref: EMBL:BC050736 xref: EMBL:BT007300 xref: EMBL:U73379 xref: HGNC:HGNC:15937 xref: UniGene:Hs.93002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001354 ! UBE2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005861 name: UBE2N_human def: "Ubiquitin-conjugating enzyme E2 N gene" [UniProtKB:P61088] synonym: "BLU" EXACT [UniProtKB:P61088] xref: EMBL:BC000396 xref: EMBL:BC003365 xref: EMBL:BC108704 xref: EMBL:BT006873 xref: EMBL:D83004 xref: HGNC:HGNC:12492 xref: UniGene:Hs.524630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005869 ! UBE2N_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005862 name: UBE3A_human def: "Ubiquitin-protein ligase E3A gene" [UniProtKB:Q05086] synonym: "E6AP" EXACT [UniProtKB:Q05086] synonym: "EPVE6AP" EXACT [UniProtKB:Q05086] synonym: "HPVE6A" EXACT [UniProtKB:Q05086] xref: EMBL:AC100774 xref: EMBL:AC124997 xref: EMBL:AF016703 xref: EMBL:AF016704 xref: EMBL:AF016705 xref: EMBL:AF016706 xref: EMBL:AF016707 xref: EMBL:AF016708 xref: EMBL:AJ001107 xref: EMBL:AJ001108 xref: EMBL:AJ001109 xref: EMBL:AJ001110 xref: EMBL:AJ001111 xref: EMBL:AJ001112 xref: EMBL:L07557 xref: EMBL:U84404 xref: EMBL:X98021 xref: EMBL:X98022 xref: EMBL:X98023 xref: EMBL:X98024 xref: EMBL:X98025 xref: EMBL:X98026 xref: EMBL:X98027 xref: EMBL:X98028 xref: EMBL:X98029 xref: EMBL:X98030 xref: EMBL:X98031 xref: EMBL:X98032 xref: EMBL:X98033 xref: HGNC:HGNC:12496 xref: UniGene:Hs.654383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005334 ! UBE3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005863 name: RPS27A_human def: "Ubiquitin gene" [UniProtKB:P62988] synonym: "UBA80" EXACT [UniProtKB:P62988] synonym: "UBCEP1" EXACT [UniProtKB:P62988] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001695 ! UBIQ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005864 name: UBA52_human def: "60S ribosomal protein L40 gene" [UniProtKB:P62987] synonym: "UBCEP2" EXACT [UniProtKB:P62987] xref: EMBL:AC005253 xref: EMBL:AF348700 xref: EMBL:X56997 xref: EMBL:X56998 xref: EMBL:X56999 xref: EMBL:Y00361 xref: HGNC:HGNC:12458 xref: UniGene:Hs.5308 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001695 ! UBIQ_HUMAN relationship: codes_for CCO:B0063107 ! RL40_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005865 name: UBB_human def: "Ubiquitin gene" [UniProtKB:P62988] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001695 ! UBIQ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005866 name: UBC_human def: "Ubiquitin gene" [UniProtKB:P62988] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001695 ! UBIQ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005867 name: UBL5_human def: "Ubiquitin-like protein 5 gene" [UniProtKB:Q9BZL1] xref: EMBL:AF313915 xref: EMBL:BC007053 xref: EMBL:BC110839 xref: EMBL:BT007355 xref: HGNC:HGNC:13736 xref: UniGene:Hs.534477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005932 ! UBL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005868 name: USP16_human def: "Ubiquitin carboxyl-terminal hydrolase 16 gene" [UniProtKB:Q9Y5T5] xref: EMBL:AF126736 xref: EMBL:AL163249 xref: EMBL:BC030777 xref: HGNC:HGNC:12614 xref: UniGene:Hs.99819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002259 ! UBP16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005869 name: USP4_human def: "Ubiquitin carboxyl-terminal hydrolase 4 gene" [UniProtKB:Q13107] synonym: "UNP" EXACT [UniProtKB:Q13107] synonym: "UNPH" EXACT [UniProtKB:Q13107] xref: EMBL:AF017305 xref: EMBL:AF017306 xref: EMBL:BC125130 xref: EMBL:U20657 xref: HGNC:HGNC:12627 xref: UniGene:Hs.631919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006305 ! UBP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005870 name: USP5_human def: "Ubiquitin carboxyl-terminal hydrolase 5 gene" [UniProtKB:P45974] synonym: "ISOT" EXACT [UniProtKB:P45974] xref: EMBL:BC004889 xref: EMBL:BC005139 xref: EMBL:U35116 xref: EMBL:U47924 xref: EMBL:U47927 xref: EMBL:X91349 xref: HGNC:HGNC:12628 xref: UniGene:Hs.631661 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005310 ! UBP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005871 name: USP7_human def: "Ubiquitin carboxyl-terminal hydrolase 7 gene" [UniProtKB:Q93009] synonym: "HAUSP" EXACT [UniProtKB:Q93009] xref: EMBL:AC022167 xref: EMBL:CH471112 xref: EMBL:Z72499 xref: HGNC:HGNC:12630 xref: UniGene:Hs.386939 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005429 ! UBP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005872 name: UBQLN1_human def: "Ubiquilin-1 gene" [UniProtKB:Q9UMX0] synonym: "DA41" EXACT [UniProtKB:Q9UMX0] synonym: "PLIC1" EXACT [UniProtKB:Q9UMX0] xref: EMBL:AB035275 xref: EMBL:AF176069 xref: EMBL:AF293384 xref: EMBL:AK074535 xref: EMBL:AL136643 xref: EMBL:BC010066 xref: EMBL:BC039294 xref: HGNC:HGNC:12508 xref: UniGene:Hs.9589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005181 ! UBQL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005873 name: UBQLN4_human def: "Ubiquilin-4 gene" [UniProtKB:Q9NRR5] synonym: "C1orf6" EXACT [UniProtKB:Q9NRR5] synonym: "UBIN" EXACT [UniProtKB:Q9NRR5] xref: EMBL:AF113544 xref: EMBL:AF188240 xref: EMBL:AL355388 xref: EMBL:BC006410 xref: EMBL:BC018403 xref: EMBL:BC063841 xref: HGNC:HGNC:1237 xref: UniGene:Hs.283739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005619 ! UBQL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005874 name: UBR1_human def: "E3 ubiquitin-protein ligase UBR1 gene" [UniProtKB:Q8IWV7] xref: EMBL:AF061556 xref: EMBL:AF067380 xref: EMBL:AF067381 xref: EMBL:AF067382 xref: EMBL:AF067383 xref: EMBL:AF067384 xref: EMBL:AF067385 xref: EMBL:AF067386 xref: EMBL:AF067387 xref: EMBL:AF525401 xref: EMBL:AK027803 xref: EMBL:AY061886 xref: EMBL:BC113505 xref: EMBL:BC113507 xref: EMBL:CR749326 xref: HGNC:HGNC:16808 xref: UniGene:Hs.591121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006135 ! UBR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005875 name: UCHL1_human def: "Ubiquitin carboxyl-terminal hydrolase isozyme L1 gene" [UniProtKB:P09936] xref: EMBL:AF060834 xref: EMBL:AF076269 xref: EMBL:AF076270 xref: EMBL:AF076271 xref: EMBL:AF076272 xref: EMBL:AF076273 xref: EMBL:BC000332 xref: EMBL:BC005117 xref: EMBL:BC006305 xref: EMBL:X04741 xref: EMBL:X17377 xref: HGNC:HGNC:12513 xref: UniGene:Hs.518731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005541 ! UCHL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005877 name: AXL_human def: "Tyrosine-protein kinase receptor UFO precursor gene" [UniProtKB:P30530] synonym: "UFO" EXACT [UniProtKB:P30530] xref: EMBL:M76125 xref: EMBL:S65125 xref: EMBL:X57019 xref: HGNC:HGNC:905 xref: UniGene:Hs.590970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001579 ! UFO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005878 name: UHMK1_human def: "Serine/threonine-protein kinase Kist gene" [UniProtKB:Q8TAS1] synonym: "KIS" EXACT [UniProtKB:Q8TAS1] synonym: "KIST" EXACT [UniProtKB:Q8TAS1] xref: EMBL:AJ536197 xref: EMBL:AL359699 xref: EMBL:BC014917 xref: EMBL:BC026046 xref: HGNC:HGNC:19683 xref: UniGene:Hs.127310 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001988 ! UHMK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005879 name: UHRF1_human def: "E3 ubiquitin-protein ligase UHRF1 gene" [UniProtKB:Q96T88] synonym: "ICBP90" EXACT [UniProtKB:Q96T88] synonym: "NP95" EXACT [UniProtKB:Q96T88] synonym: "RNF106" EXACT [UniProtKB:Q96T88] xref: EMBL:AB075601 xref: EMBL:AC027319 xref: EMBL:AC053467 xref: EMBL:AF129507 xref: EMBL:AF274048 xref: EMBL:AK025578 xref: EMBL:AY787925 xref: HGNC:HGNC:12556 xref: UniGene:Hs.108106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002063 ! UHRF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005880 name: UHRF2_human def: "E3 ubiquitin-protein ligase UHRF2 gene" [UniProtKB:Q96PU4] synonym: "NIRF" EXACT [UniProtKB:Q96PU4] synonym: "RNF107" EXACT [UniProtKB:Q96PU4] xref: EMBL:AB071698 xref: EMBL:AF274049 xref: EMBL:AL133480 xref: EMBL:AL137728 xref: EMBL:AL353718 xref: EMBL:BC028397 xref: HGNC:HGNC:12557 xref: UniGene:Hs.493401 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002054 ! UHRF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005882 name: ULK2_human def: "Serine/threonine-protein kinase ULK2 gene" [UniProtKB:Q8IYT8] synonym: "KIAA0623" EXACT [UniProtKB:Q8IYT8] xref: EMBL:AB014523 xref: EMBL:AC005722 xref: EMBL:BC034988 xref: HGNC:HGNC:13480 xref: UniGene:Hs.168762 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006252 ! ULK2_HUMAN relationship: codes_for CCO:B0054114 ! A8MY69_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005883 name: UNC119_human def: "Protein unc-119 homolog A gene" [UniProtKB:Q13432] synonym: "RG4" EXACT [UniProtKB:Q13432] xref: EMBL:AF028788 xref: EMBL:AF028789 xref: EMBL:AF125997 xref: EMBL:AF125998 xref: EMBL:BC027176 xref: EMBL:U40998 xref: HGNC:HGNC:12565 xref: UniGene:Hs.410455 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043869 ! U119A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005884 name: UNC84B_human def: "Protein unc-84 homolog B gene" [UniProtKB:Q9UH99] synonym: "FRIGG" EXACT [UniProtKB:Q9UH99] synonym: "KIAA0668" EXACT [UniProtKB:Q9UH99] synonym: "RAB5IP" EXACT [UniProtKB:Q9UH99] synonym: "SUN2" EXACT [UniProtKB:Q9UH99] xref: EMBL:AB014568 xref: EMBL:AF202723 xref: EMBL:AL021707 xref: EMBL:AY682988 xref: EMBL:BC030684 xref: EMBL:BC111717 xref: EMBL:BX537962 xref: EMBL:CR456474 xref: HGNC:HGNC:14210 xref: UniGene:Hs.517622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002199 ! UN84B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005886 name: URM1_human def: "Ubiquitin-related modifier 1 homolog gene" [UniProtKB:Q9BTM9] synonym: "C9orf74" EXACT [UniProtKB:Q9BTM9] xref: EMBL:AL359091 xref: EMBL:BC003581 xref: HGNC:HGNC:28378 xref: UniGene:Hs.495229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006312 ! URM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005887 name: USHBP1_human def: "USH1C-binding protein 1 gene" [UniProtKB:Q8N6Y0] synonym: "AIEBP" EXACT [UniProtKB:Q8N6Y0] synonym: "MCC2" EXACT [UniProtKB:Q8N6Y0] xref: EMBL:AB026290 xref: EMBL:AB040046 xref: EMBL:AK075162 xref: EMBL:BC027910 xref: HGNC:HGNC:24058 xref: UniGene:Hs.512773 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005210 ! USBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005888 name: USH1C_human def: "Harmonin gene" [UniProtKB:Q9Y6N9] synonym: "AIE75" EXACT [UniProtKB:Q9Y6N9] xref: EMBL:AB006955 xref: EMBL:AB018687 xref: EMBL:AF039699 xref: EMBL:AF039700 xref: EMBL:BC016057 xref: HGNC:HGNC:12597 xref: UniGene:Hs.502072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002265 ! USH1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005889 name: UTP14A_human def: "U3 small nucleolar RNA-associated protein 14 homolog A gene" [UniProtKB:Q9BVJ6] synonym: "SDCCAG16" EXACT [UniProtKB:Q9BVJ6] xref: EMBL:AL034405 xref: EMBL:BC001149 xref: EMBL:BC009649 xref: EMBL:BC014987 xref: HGNC:HGNC:10665 xref: UniGene:Hs.458598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006134 ! UT14A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005890 name: UTP14C_human def: "U3 small nucleolar RNA-associated protein 14 homolog C gene" [UniProtKB:Q5TAP6] synonym: "KIAA0266" EXACT [UniProtKB:Q5TAP6] xref: EMBL:AL139082 xref: EMBL:BC089407 xref: EMBL:D87455 xref: HGNC:HGNC:20321 xref: UniGene:Hs.512963 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001882 ! UT14C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005891 name: UTP6_human def: "U3 small nucleolar RNA-associated protein 6 homolog gene" [UniProtKB:Q9NYH9] synonym: "C17orf40" EXACT [UniProtKB:Q9NYH9] synonym: "HCA66" EXACT [UniProtKB:Q9NYH9] synonym: "MHAT" EXACT [UniProtKB:Q9NYH9] xref: EMBL:AF244135 xref: EMBL:AF334386 xref: EMBL:AJ272197 xref: EMBL:BC015454 xref: EMBL:BC035325 xref: HGNC:HGNC:18279 xref: UniGene:Hs.589862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006050 ! UTP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005892 name: VAMP8_human def: "Vesicle-associated membrane protein 8 gene" [UniProtKB:Q9BV40] xref: EMBL:AC016753 xref: EMBL:AF053233 xref: EMBL:BC001634 xref: EMBL:BT006700 xref: EMBL:CR456995 xref: HGNC:HGNC:12647 xref: UniGene:Hs.534373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006350 ! VAMP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005893 name: VASH1_human def: "Vasohibin-1 gene" [UniProtKB:Q7L8A9] synonym: "KIAA1036" EXACT [UniProtKB:Q7L8A9] synonym: "VASH" EXACT [UniProtKB:Q7L8A9] xref: EMBL:AB028959 xref: EMBL:AC007376 xref: EMBL:AF111169 xref: EMBL:AL832588 xref: EMBL:BC009031 xref: EMBL:BC051896 xref: HGNC:HGNC:19964 xref: UniGene:Hs.525479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001931 ! VASH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005894 name: VDAC1_human def: "Voltage-dependent anion-selective channel protein 1 gene" [UniProtKB:P21796] synonym: "VDAC" EXACT [UniProtKB:P21796] xref: EMBL:AC005200 xref: EMBL:AC008608 xref: EMBL:AF151093 xref: EMBL:AF151094 xref: EMBL:AF151095 xref: EMBL:AF151096 xref: EMBL:AF151097 xref: EMBL:AJ250032 xref: EMBL:AJ250033 xref: EMBL:AJ250034 xref: EMBL:AJ250035 xref: EMBL:AJ250036 xref: EMBL:AJ250037 xref: EMBL:AJ250038 xref: EMBL:AJ250039 xref: EMBL:BC008482 xref: EMBL:BC071168 xref: EMBL:BC090042 xref: EMBL:L06132 xref: HGNC:HGNC:12669 xref: UniGene:Hs.519320 xref: UniGene:Hs.644647 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005765 ! VDAC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005895 name: VDAC2_human def: "Voltage-dependent anion-selective channel protein 2 gene" [UniProtKB:P45880] xref: EMBL:AF152220 xref: EMBL:AF152221 xref: EMBL:AF152222 xref: EMBL:AF152223 xref: EMBL:AF152224 xref: EMBL:AF152225 xref: EMBL:AF152226 xref: EMBL:AF152227 xref: EMBL:AL390034 xref: EMBL:AL392111 xref: EMBL:BC000165 xref: EMBL:BC012883 xref: EMBL:BC072407 xref: EMBL:CR456964 xref: EMBL:L06328 xref: EMBL:L08666 xref: HGNC:HGNC:12672 xref: UniGene:Hs.355927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005777 ! VDAC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005896 name: VDAC3_human def: "Voltage-dependent anion-selective channel protein 3 gene" [UniProtKB:Q9Y277] xref: EMBL:AF038962 xref: EMBL:AF151679 xref: EMBL:AF151681 xref: EMBL:AF151682 xref: EMBL:BC056870 xref: EMBL:U90943 xref: HGNC:HGNC:12674 xref: UniGene:Hs.655340 xref: UniGene:Hs.699301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005738 ! VDAC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005897 name: VEGF_human def: "Vascular endothelial growth factor gene" [UniProtKB:A2A2V4] synonym: "RP1-261G23.1-009" EXACT [UniProtKB:A2A2V4] xref: EMBL:AL136131 xref: EMBL:AY263145 xref: HGNC:HGNC:12680 xref: UniGene:Hs.73793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001920 ! Q6WZM0_HUMAN relationship: codes_for CCO:B0025531 ! A2A2V4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005898 name: VEGFB_human def: "Vascular endothelial growth factor B precursor gene" [UniProtKB:P49765] synonym: "VRF" EXACT [UniProtKB:P49765] xref: EMBL:BC008818 xref: EMBL:U43368 xref: EMBL:U43369 xref: EMBL:U48801 xref: EMBL:U52819 xref: HGNC:HGNC:12681 xref: UniGene:Hs.78781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001634 ! VEGFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005899 name: VEGFC_human def: "Vascular endothelial growth factor C precursor gene" [UniProtKB:P49767] xref: EMBL:BC035212 xref: EMBL:BC063685 xref: EMBL:U43142 xref: EMBL:U58111 xref: EMBL:X94216 xref: HGNC:HGNC:12682 xref: UniGene:Hs.435215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001635 ! VEGFC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005900 name: FIGF_human def: "Vascular endothelial growth factor D precursor gene" [UniProtKB:O43915] synonym: "VEGFD" EXACT [UniProtKB:O43915] xref: EMBL:AJ000185 xref: EMBL:BC027948 xref: EMBL:D89630 xref: EMBL:Y12863 xref: EMBL:Y12864 xref: EMBL:Y12865 xref: EMBL:Y12866 xref: EMBL:Y12867 xref: EMBL:Y12868 xref: EMBL:Y12869 xref: EMBL:Y12870 xref: HGNC:HGNC:3708 xref: UniGene:Hs.11392 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001402 ! VEGFD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005901 name: FLT1_human def: "Vascular endothelial growth factor receptor 1 precursor gene" [UniProtKB:P17948] synonym: "FLT" EXACT [UniProtKB:P17948] synonym: "FRT" EXACT [UniProtKB:P17948] xref: EMBL:AF063657 xref: EMBL:BC039007 xref: EMBL:D00133 xref: EMBL:U01134 xref: EMBL:X51602 xref: HGNC:HGNC:3763 xref: UniGene:Hs.654360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005719 ! VGFR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005902 name: VHL_human def: "Von Hippel-Lindau disease tumor suppressor gene" [UniProtKB:P40337] xref: EMBL:AF010238 xref: EMBL:L15409 xref: EMBL:U54612 xref: EMBL:X96489 xref: HGNC:HGNC:12687 xref: UniGene:Hs.517792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001600 ! VHL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005903 name: VIM_human def: "Vimentin gene" [UniProtKB:P08670] xref: EMBL:AF328728 xref: EMBL:AK056766 xref: EMBL:AK097336 xref: EMBL:AK222507 xref: EMBL:AK222602 xref: EMBL:AK290643 xref: EMBL:AL133415 xref: EMBL:BC000163 xref: EMBL:BC030573 xref: EMBL:BC066956 xref: EMBL:CH471072 xref: EMBL:CR407690 xref: EMBL:M14144 xref: EMBL:M18888 xref: EMBL:M18889 xref: EMBL:M18890 xref: EMBL:M18891 xref: EMBL:M18892 xref: EMBL:M18893 xref: EMBL:M18894 xref: EMBL:M18895 xref: EMBL:M25246 xref: EMBL:X16478 xref: EMBL:X56134 xref: EMBL:Z19554 xref: HGNC:HGNC:12692 xref: UniGene:Hs.642813 xref: UniGene:Hs.704019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005737 ! VIME_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005904 name: VSNL1_human def: "Visinin-like protein 1 gene" [UniProtKB:P62760] synonym: "VISL1" EXACT [UniProtKB:P62760] xref: EMBL:AB001104 xref: EMBL:AF039555 xref: EMBL:BC022012 xref: EMBL:U14747 xref: HGNC:HGNC:12722 xref: UniGene:Hs.444212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005986 ! VISL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005905 name: VPS29_human def: "Vacuolar protein sorting-associated protein 29 gene" [UniProtKB:Q9UBQ0] synonym: "DC15" EXACT [UniProtKB:Q9UBQ0] synonym: "DC7" EXACT [UniProtKB:Q9UBQ0] synonym: "MDS007" EXACT [UniProtKB:Q9UBQ0] xref: EMBL:AF168716 xref: EMBL:AF175264 xref: EMBL:AF193795 xref: EMBL:AF201936 xref: EMBL:AF201946 xref: EMBL:AL136614 xref: EMBL:BC000880 xref: EMBL:BC095446 xref: EMBL:CR457182 xref: EMBL:CR533468 xref: HGNC:HGNC:14340 xref: UniGene:Hs.632735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006299 ! VPS29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005906 name: VPS72_human def: "Vacuolar protein sorting-associated protein 72 homolog gene" [UniProtKB:Q15906] synonym: "TCFL1" EXACT [UniProtKB:Q15906] synonym: "YL1" EXACT [UniProtKB:Q15906] xref: EMBL:AK222935 xref: EMBL:AK222939 xref: EMBL:AL592424 xref: EMBL:BC003151 xref: EMBL:BT019356 xref: EMBL:BT019357 xref: EMBL:CH471121 xref: EMBL:D43642 xref: HGNC:HGNC:11644 xref: UniGene:Hs.2430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005361 ! VPS72_HUMAN relationship: codes_for CCO:B0053937 ! A6PW55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005907 name: VRK2_human def: "Serine/threonine-protein kinase VRK2 gene" [UniProtKB:Q86Y07] xref: EMBL:AB000450 xref: EMBL:AJ512204 xref: EMBL:AK223540 xref: EMBL:AY228367 xref: EMBL:AY228368 xref: EMBL:AY228369 xref: EMBL:AY228370 xref: EMBL:AY228371 xref: EMBL:AY228372 xref: EMBL:BC027854 xref: EMBL:BC036434 xref: HGNC:HGNC:12719 xref: UniGene:Hs.631890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005928 ! VRK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005908 name: VTA1_human def: "Vacuolar protein sorting-associated protein VTA1 homolog gene" [UniProtKB:Q9NP79] synonym: "C6orf55" EXACT [UniProtKB:Q9NP79] synonym: "HSPC228" EXACT [UniProtKB:Q9NP79] synonym: "My012" EXACT [UniProtKB:Q9NP79] xref: EMBL:AF060225 xref: EMBL:AF151062 xref: EMBL:AF271994 xref: EMBL:AK000051 xref: EMBL:AL033522 xref: EMBL:AL136684 xref: EMBL:BC005937 xref: EMBL:BC006989 xref: EMBL:BC022536 xref: EMBL:CR457207 xref: HGNC:HGNC:20954 xref: UniGene:Hs.431367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005259 ! VTA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005909 name: GC_human def: "Vitamin D-binding protein precursor gene" [UniProtKB:P02774] xref: EMBL:L10641 xref: EMBL:M12654 xref: EMBL:M17156 xref: EMBL:S67474 xref: EMBL:S67476 xref: EMBL:S67478 xref: EMBL:S67479 xref: EMBL:S67480 xref: EMBL:S67526 xref: EMBL:S77129 xref: EMBL:S77130 xref: EMBL:X03178 xref: HGNC:HGNC:4187 xref: UniGene:Hs.418497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006193 ! VTDB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005910 name: WAPAL_human def: "Wings apart-like protein homolog gene" [UniProtKB:Q7Z5K2] synonym: "FOE" EXACT [UniProtKB:Q7Z5K2] synonym: "KIAA0261" EXACT [UniProtKB:Q7Z5K2] synonym: "WAPL" EXACT [UniProtKB:Q7Z5K2] xref: EMBL:AB065003 xref: EMBL:AF479418 xref: EMBL:AL731569 xref: EMBL:AL844892 xref: EMBL:D87450 xref: HGNC:HGNC:23293 xref: UniGene:Hs.203099 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005721 ! WAPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005911 name: WASL_human def: "Neural Wiskott-Aldrich syndrome protein gene" [UniProtKB:O00401] xref: EMBL:AC006333 xref: EMBL:BC052955 xref: EMBL:D88460 xref: HGNC:HGNC:12735 xref: UniGene:Hs.143728 xref: UniGene:Hs.700974 xref: UniGene:Hs.83916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005942 ! WASL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005912 name: WBP11_human def: "WW domain-binding protein 11 gene" [UniProtKB:Q9Y2W2] synonym: "NPWBP" EXACT [UniProtKB:Q9Y2W2] synonym: "SNP70" EXACT [UniProtKB:Q9Y2W2] xref: EMBL:AB029309 xref: EMBL:AF118023 xref: EMBL:BC001621 xref: EMBL:BC016441 xref: EMBL:BC023532 xref: HGNC:HGNC:16461 xref: UniGene:Hs.655138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005313 ! WBP11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005913 name: WBP2NL_human def: "Postacrosomal sheath WW domain-binding protein gene" [UniProtKB:Q6ICG8] synonym: "PAWP" EXACT [UniProtKB:Q6ICG8] xref: EMBL:AF393575 xref: EMBL:BC022546 xref: EMBL:BC022549 xref: EMBL:CR456400 xref: EMBL:Z99716 xref: HGNC:HGNC:28389 xref: UniGene:Hs.655541 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001907 ! WBP2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005914 name: WBP2_human def: "WW domain-binding protein 2 gene" [UniProtKB:Q969T9] xref: EMBL:BC007452 xref: EMBL:BC010616 xref: EMBL:U79458 xref: HGNC:HGNC:12738 xref: UniGene:Hs.514489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006351 ! WBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005915 name: WBP7_human def: "Histone-lysine N-methyltransferase MLL4 gene" [UniProtKB:Q9UMN6] synonym: "HRX2" EXACT [UniProtKB:Q9UMN6] synonym: "KIAA0304" EXACT [UniProtKB:Q9UMN6] synonym: "KMT2D" EXACT [UniProtKB:Q9UMN6] synonym: "MLL2" EXACT [UniProtKB:Q9UMN6] synonym: "MLL4" EXACT [UniProtKB:Q9UMN6] synonym: "TRX2" EXACT [UniProtKB:Q9UMN6] xref: EMBL:AB002302 xref: EMBL:AD000671 xref: EMBL:AF104918 xref: EMBL:AF105279 xref: EMBL:AF105280 xref: EMBL:AF186605 xref: EMBL:AJ007041 xref: EMBL:BC007353 xref: EMBL:BC009337 xref: UniGene:Hs.676457 xref: UniGene:Hs.92236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043865 ! MLL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005916 name: WDR51B_human def: "WD repeat-containing protein 51B gene" [UniProtKB:Q8TC44] xref: EMBL:AK074772 xref: EMBL:BC026080 xref: HGNC:HGNC:30836 xref: UniGene:Hs.705416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005998 ! WD51B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005917 name: WDR26_human def: "WD repeat-containing protein 26 gene" [UniProtKB:Q9H7D7] synonym: "CDW2" EXACT [UniProtKB:Q9H7D7] synonym: "MIP2" EXACT [UniProtKB:Q9H7D7] synonym: "PRO0852" EXACT [UniProtKB:Q9H7D7] xref: EMBL:AB209887 xref: EMBL:AF130049 xref: EMBL:AK024669 xref: EMBL:AY221751 xref: EMBL:AY304473 xref: EMBL:BC031471 xref: EMBL:BC034498 xref: EMBL:BC052301 xref: EMBL:BC063817 xref: EMBL:EF011612 xref: HGNC:HGNC:21208 xref: UniGene:Hs.497873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005689 ! WDR26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005918 name: WDR33_human def: "WD repeat-containing protein 33 gene" [UniProtKB:Q9C0J8] synonym: "WDC146" EXACT [UniProtKB:Q9C0J8] xref: EMBL:AB044749 xref: EMBL:AC006011 xref: EMBL:CH471103 xref: HGNC:HGNC:25651 xref: UniGene:Hs.620490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006169 ! WDR33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005919 name: WDR35_human def: "WD repeat-containing protein 35 gene" [UniProtKB:Q9P2L0] synonym: "KIAA1336" EXACT [UniProtKB:Q9P2L0] xref: EMBL:AB037757 xref: EMBL:BC036659 xref: HGNC:HGNC:29250 xref: UniGene:Hs.205427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006025 ! WDR35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005920 name: WDR47_human def: "WD repeat-containing protein 47 gene" [UniProtKB:O94967] synonym: "KIAA0893" EXACT [UniProtKB:O94967] xref: EMBL:AB020700 xref: EMBL:AK289789 xref: EMBL:AL449266 xref: EMBL:BC034964 xref: EMBL:BC039254 xref: EMBL:BX679664 xref: EMBL:CH471122 xref: HGNC:HGNC:29141 xref: UniGene:Hs.654760 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006319 ! WDR47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005921 name: WDR57_human def: "WD repeat-containing protein 57 gene" [UniProtKB:Q96DI7] synonym: "PRP8BP" EXACT [UniProtKB:Q96DI7] synonym: "SFP38" EXACT [UniProtKB:Q96DI7] xref: EMBL:AC114495 xref: EMBL:AF083383 xref: EMBL:AF090988 xref: EMBL:AL451070 xref: EMBL:BC001494 xref: HGNC:HGNC:30857 xref: UniGene:Hs.33962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005996 ! WDR57_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005922 name: WDR5B_human def: "WD repeat-containing protein 5B gene" [UniProtKB:Q86VZ2] xref: EMBL:AK002149 xref: EMBL:BC043494 xref: EMBL:CR457279 xref: HGNC:HGNC:17826 xref: UniGene:Hs.567513 xref: UniGene:Hs.594258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006000 ! WDR5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005923 name: WDR5_human def: "WD repeat-containing protein 5 gene" [UniProtKB:P61964] synonym: "BIG3" EXACT [UniProtKB:P61964] xref: EMBL:AJ011376 xref: EMBL:AK000552 xref: EMBL:BC001635 xref: HGNC:HGNC:12757 xref: UniGene:Hs.397638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005615 ! WDR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005924 name: WDR61_human def: "WD repeat-containing protein 61 gene" [UniProtKB:Q9GZS3] xref: EMBL:AF100786 xref: EMBL:AF127799 xref: EMBL:AF309553 xref: EMBL:AK024754 xref: EMBL:BC010080 xref: EMBL:CR457333 xref: HGNC:HGNC:30300 xref: UniGene:Hs.513055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005999 ! WDR61_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005925 name: WDR62_human def: "WD repeat-containing protein 62 gene" [UniProtKB:O43379] synonym: "C19orf14" EXACT [UniProtKB:O43379] xref: EMBL:AC004144 xref: EMBL:AD000813 xref: EMBL:AK090617 xref: EMBL:AL133651 xref: EMBL:BC017261 xref: EMBL:BX647726 xref: HGNC:HGNC:24502 xref: UniGene:Hs.116244 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006173 ! WDR62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005926 name: WDR74_human def: "WD repeat-containing protein 74 gene" [UniProtKB:Q6RFH5] synonym: "NSA1" EXACT [UniProtKB:Q6RFH5] xref: EMBL:AK001301 xref: EMBL:AK025383 xref: EMBL:AY500828 xref: EMBL:BC006351 xref: HGNC:HGNC:25529 xref: UniGene:Hs.654620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006296 ! WDR74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005927 name: WDR76_human def: "WD repeat-containing protein 76 gene" [UniProtKB:Q9H967] xref: EMBL:AK023035 xref: EMBL:AK290933 xref: EMBL:BC025247 xref: EMBL:BC051855 xref: EMBL:EF011624 xref: HGNC:HGNC:25773 xref: UniGene:Hs.250154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005997 ! WDR76_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005928 name: WDR82_human def: "WD repeat-containing protein 82 gene" [UniProtKB:Q6UXN9] synonym: "UNQ9342/PRO34047" EXACT [UniProtKB:Q6UXN9] synonym: "WDR82A" EXACT [UniProtKB:Q6UXN9] xref: EMBL:AK074290 xref: EMBL:AY358264 xref: HGNC:HGNC:28826 xref: UniGene:Hs.194110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005688 ! WDR82_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005929 name: WEE1_human def: "Wee1-like protein kinase gene" [UniProtKB:P30291] xref: EMBL:AJ277546 xref: EMBL:U10564 xref: EMBL:X62048 xref: HGNC:HGNC:12761 xref: UniGene:Hs.249441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001575 ! WEE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005930 name: WFDC2_human def: "WAP four-disulfide core domain protein 2 precursor gene" [UniProtKB:Q14508] synonym: "HE4" EXACT [UniProtKB:Q14508] synonym: "WAP5" EXACT [UniProtKB:Q14508] xref: EMBL:AF330259 xref: EMBL:AF330260 xref: EMBL:AF330261 xref: EMBL:AF330262 xref: EMBL:AL031663 xref: EMBL:AY212888 xref: EMBL:BC046106 xref: EMBL:CR456977 xref: EMBL:X63187 xref: HGNC:HGNC:15939 xref: UniGene:Hs.2719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006308 ! WFDC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005931 name: WNK4_human def: "Serine/threonine-protein kinase WNK4 gene" [UniProtKB:Q96J92] synonym: "PRKWNK4" EXACT [UniProtKB:Q96J92] xref: EMBL:AF390018 xref: EMBL:AJ309861 xref: EMBL:AJ316534 xref: EMBL:AK096003 xref: EMBL:AK096052 xref: HGNC:HGNC:14544 xref: UniGene:Hs.105448 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005934 ! WNK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005932 name: WNT16_human def: "Protein Wnt-16 precursor gene" [UniProtKB:Q9UBV4] xref: EMBL:AC006364 xref: EMBL:AF152584 xref: EMBL:AF169963 xref: EMBL:BC104919 xref: EMBL:BC104945 xref: HGNC:HGNC:16267 xref: UniGene:Hs.272375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006047 ! WNT16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005933 name: WRN_human def: "Werner syndrome ATP-dependent helicase gene" [UniProtKB:Q14191] synonym: "RECQ3" EXACT [UniProtKB:Q14191] synonym: "RECQL2" EXACT [UniProtKB:Q14191] xref: EMBL:AF091214 xref: EMBL:AF181896 xref: EMBL:AF181897 xref: EMBL:AY442327 xref: EMBL:L76937 xref: HGNC:HGNC:12791 xref: UniGene:Hs.632050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005358 ! WRN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005934 name: WT1_human def: "Wilms tumor protein gene" [UniProtKB:P19544] xref: EMBL:AL049692 xref: EMBL:AY245105 xref: EMBL:BC032861 xref: EMBL:M30393 xref: EMBL:M80217 xref: EMBL:M80218 xref: EMBL:M80219 xref: EMBL:M80220 xref: EMBL:M80221 xref: EMBL:M80228 xref: EMBL:M80229 xref: EMBL:M80231 xref: EMBL:M80232 xref: EMBL:S60755 xref: EMBL:S61515 xref: EMBL:S61522 xref: EMBL:S61524 xref: EMBL:S75264 xref: EMBL:X51630 xref: EMBL:X61631 xref: EMBL:X61632 xref: EMBL:X61633 xref: EMBL:X61634 xref: EMBL:X61635 xref: EMBL:X61636 xref: EMBL:X61637 xref: EMBL:X61638 xref: HGNC:HGNC:12796 xref: UniGene:Hs.591980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001536 ! WT1_HUMAN relationship: codes_for CCO:B0018552 ! Q4VXV6_HUMAN relationship: codes_for CCO:B0018555 ! Q4VXV5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005935 name: WWC1_human def: "Protein WWC1 gene" [UniProtKB:Q8IX03] synonym: "KIAA0869" EXACT [UniProtKB:Q8IX03] xref: EMBL:AB020676 xref: EMBL:AF506799 xref: EMBL:AF530058 xref: EMBL:AY189820 xref: EMBL:BC004394 xref: EMBL:BC017746 xref: EMBL:BX640827 xref: HGNC:HGNC:29435 xref: UniGene:Hs.484047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006200 ! WWC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005936 name: WWOX_human def: "WW domain-containing oxidoreductase gene" [UniProtKB:Q9NZC7] synonym: "FOR" EXACT [UniProtKB:Q9NZC7] synonym: "WOX1" EXACT [UniProtKB:Q9NZC7] xref: EMBL:AF211943 xref: EMBL:AF212843 xref: EMBL:AF217490 xref: EMBL:AF217491 xref: EMBL:AF217492 xref: EMBL:AF227526 xref: EMBL:AF227527 xref: EMBL:AF227528 xref: EMBL:AF227529 xref: EMBL:AF325423 xref: EMBL:AF325424 xref: EMBL:AF325425 xref: EMBL:AF325426 xref: EMBL:AF325427 xref: EMBL:AF325428 xref: EMBL:AF325429 xref: EMBL:AF325430 xref: EMBL:AF325431 xref: EMBL:AF325432 xref: EMBL:AF325433 xref: EMBL:AF395123 xref: EMBL:AF395124 xref: EMBL:AY256821 xref: EMBL:BC003184 xref: EMBL:BT007445 xref: HGNC:HGNC:12799 xref: UniGene:Hs.461453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002181 ! WWOX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005937 name: HBXIP_human def: "Hepatitis B virus X-interacting protein gene" [UniProtKB:O43504] synonym: "XIP" EXACT [UniProtKB:O43504] xref: EMBL:AF029890 xref: EMBL:AL390797 xref: EMBL:AY623819 xref: EMBL:BC062619 xref: EMBL:CR456866 xref: EMBL:CR542130 xref: HGNC:HGNC:17955 xref: UniGene:Hs.439815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041278 ! HBXIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005938 name: XPA_human def: "DNA repair protein complementing XP-A cells gene" [UniProtKB:P23025] synonym: "XPAC" EXACT [UniProtKB:P23025] xref: EMBL:AF503166 xref: EMBL:BC014965 xref: EMBL:BT019518 xref: EMBL:D14533 xref: EMBL:U16815 xref: HGNC:HGNC:12814 xref: UniGene:Hs.654364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005345 ! XPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005939 name: XPC_human def: "DNA repair protein complementing XP-C cells gene" [UniProtKB:Q01831] synonym: "XPCC" EXACT [UniProtKB:Q01831] xref: EMBL:AF261892 xref: EMBL:AF261893 xref: EMBL:AF261894 xref: EMBL:AF261895 xref: EMBL:AF261896 xref: EMBL:AF261897 xref: EMBL:AF261898 xref: EMBL:AF261899 xref: EMBL:AF261900 xref: EMBL:AF261901 xref: EMBL:AK222844 xref: EMBL:AY131066 xref: EMBL:BC016620 xref: EMBL:D21089 xref: EMBL:X65024 xref: HGNC:HGNC:12816 xref: UniGene:Hs.475538 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001714 ! XPC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005940 name: XPO1_human def: "Exportin-1 gene" [UniProtKB:O14980] synonym: "CRM1" EXACT [UniProtKB:O14980] xref: EMBL:AC016727 xref: EMBL:AK289920 xref: EMBL:BC032847 xref: EMBL:BX647758 xref: EMBL:CH471053 xref: EMBL:CR749840 xref: EMBL:D89729 xref: EMBL:Y08614 xref: HGNC:HGNC:12825 xref: UniGene:Hs.370770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005867 ! XPO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005941 name: CSE1L_human def: "Exportin-2 gene" [UniProtKB:P55060] synonym: "CAS" EXACT [UniProtKB:P55060] synonym: "XPO2" EXACT [UniProtKB:P55060] xref: EMBL:AF053640 xref: EMBL:AF053641 xref: EMBL:AF053642 xref: EMBL:AF053644 xref: EMBL:AF053645 xref: EMBL:AF053646 xref: EMBL:AF053647 xref: EMBL:AF053648 xref: EMBL:AF053649 xref: EMBL:AF053650 xref: EMBL:AF053651 xref: EMBL:AL121903 xref: EMBL:AL133174 xref: EMBL:BC108309 xref: EMBL:BC109313 xref: EMBL:BC109314 xref: EMBL:U33286 xref: HGNC:HGNC:2431 xref: UniGene:Hs.90073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005662 ! XPO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005942 name: XPO7_human def: "Exportin-7 gene" [UniProtKB:Q9UIA9] synonym: "KIAA0745" EXACT [UniProtKB:Q9UIA9] synonym: "RANBP16" EXACT [UniProtKB:Q9UIA9] xref: EMBL:AB018288 xref: EMBL:AF064729 xref: EMBL:BC014219 xref: EMBL:BC030785 xref: HGNC:HGNC:14108 xref: UniGene:Hs.172685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005665 ! XPO7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005943 name: XPOT_human def: "Exportin-T gene" [UniProtKB:O43592] xref: EMBL:AC135279 xref: EMBL:AF039022 xref: EMBL:BC000950 xref: EMBL:BC020569 xref: EMBL:Y16414 xref: HGNC:HGNC:12826 xref: UniGene:Hs.85951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005664 ! XPOT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005944 name: XPNPEP1_human def: "Xaa-Pro aminopeptidase 1 gene" [UniProtKB:Q9NQW7] synonym: "XPNPEPL" EXACT [UniProtKB:Q9NQW7] synonym: "XPNPEPL1" EXACT [UniProtKB:Q9NQW7] xref: EMBL:AF195530 xref: EMBL:AF272981 xref: EMBL:AK223513 xref: EMBL:AL354951 xref: EMBL:AL833411 xref: EMBL:BC005126 xref: EMBL:BC007579 xref: EMBL:BC013417 xref: EMBL:CR456922 xref: EMBL:X95762 xref: HGNC:HGNC:12822 xref: UniGene:Hs.390623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006347 ! XPP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005945 name: XRCC2_human def: "DNA repair protein XRCC2 gene" [UniProtKB:O43543] xref: EMBL:AC003109 xref: EMBL:AF035587 xref: EMBL:AF520762 xref: EMBL:BC042137 xref: EMBL:Y08837 xref: EMBL:Y17033 xref: HGNC:HGNC:12829 xref: UniGene:Hs.647093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001392 ! XRCC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005946 name: XRCC4_human def: "DNA repair protein XRCC4 gene" [UniProtKB:Q13426] xref: EMBL:AB017445 xref: EMBL:AF055279 xref: EMBL:AF055280 xref: EMBL:AF055281 xref: EMBL:AF055282 xref: EMBL:AF055283 xref: EMBL:AF055284 xref: EMBL:AF055285 xref: EMBL:AY940097 xref: EMBL:BC005259 xref: EMBL:BC016314 xref: EMBL:BT007216 xref: EMBL:U40622 xref: HGNC:HGNC:12831 xref: UniGene:Hs.567359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005651 ! XRCC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005947 name: XRN1_human def: "5'-3' exoribonuclease 1 gene" [UniProtKB:Q8IZH2] synonym: "SEP1" EXACT [UniProtKB:Q8IZH2] xref: EMBL:AK096177 xref: EMBL:AL133623 xref: EMBL:AY137776 xref: EMBL:BC039314 xref: EMBL:BC048104 xref: EMBL:BX640905 xref: EMBL:CR627396 xref: EMBL:CR749518 xref: HGNC:HGNC:30654 xref: UniGene:Hs.435103 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001954 ! XRN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005948 name: YBX1_human def: "Nuclease-sensitive element-binding protein 1 gene" [UniProtKB:P67809] synonym: "NSEP1" EXACT [UniProtKB:P67809] synonym: "YB1" EXACT [UniProtKB:P67809] xref: EMBL:BC002411 xref: EMBL:BC010430 xref: EMBL:BC015208 xref: EMBL:BC038384 xref: EMBL:BC065571 xref: EMBL:BC070084 xref: EMBL:BC071708 xref: EMBL:BC090038 xref: EMBL:BC098435 xref: EMBL:BC106045 xref: EMBL:J03827 xref: EMBL:L28809 xref: EMBL:M24070 xref: EMBL:M83234 xref: HGNC:HGNC:8014 xref: UniGene:Hs.473583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005742 ! YBOX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005949 name: YES1_human def: "Proto-oncogene tyrosine-protein kinase Yes gene" [UniProtKB:P07947] synonym: "YES" EXACT [UniProtKB:P07947] xref: EMBL:AP001178 xref: EMBL:BC048960 xref: EMBL:CH471113 xref: EMBL:M15990 xref: HGNC:HGNC:12841 xref: UniGene:Hs.194148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005465 ! YES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005950 name: YEATS4_human def: "YEATS domain-containing protein 4 gene" [UniProtKB:O95619] synonym: "GAS41" EXACT [UniProtKB:O95619] xref: EMBL:AJ245746 xref: EMBL:AK001413 xref: EMBL:BC000994 xref: EMBL:U61384 xref: HGNC:HGNC:24859 xref: UniGene:Hs.4029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001451 ! YETS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005951 name: ZBED1_human def: "Zinc finger BED domain-containing protein 1 gene" [UniProtKB:O96006] synonym: "ALTE" EXACT [UniProtKB:O96006] synonym: "DREF" EXACT [UniProtKB:O96006] synonym: "KIAA0785" EXACT [UniProtKB:O96006] synonym: "TRAMP" EXACT [UniProtKB:O96006] xref: EMBL:AB018328 xref: EMBL:BC015030 xref: EMBL:Y16947 xref: EMBL:Y17156 xref: HGNC:HGNC:447 xref: UniGene:Hs.131452 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005231 ! ZBED1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005952 name: ZBTB17_human def: "Zinc finger and BTB domain-containing protein 17 gene" [UniProtKB:Q13105] synonym: "MIZ1" EXACT [UniProtKB:Q13105] synonym: "ZNF151" EXACT [UniProtKB:Q13105] synonym: "ZNF60" EXACT [UniProtKB:Q13105] xref: EMBL:AL034555 xref: EMBL:BC126163 xref: EMBL:M88369 xref: EMBL:U20647 xref: EMBL:Y09723 xref: HGNC:HGNC:12936 xref: UniGene:Hs.433764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001741 ! ZBT17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005953 name: ZC3H11A_human def: "Zinc finger CCCH domain-containing protein 11A gene" [UniProtKB:O75152] synonym: "KIAA0663" EXACT [UniProtKB:O75152] synonym: "ZC3HDC11A" EXACT [UniProtKB:O75152] xref: EMBL:AB014563 xref: EMBL:BC014268 xref: EMBL:BC048271 xref: EMBL:BX648271 xref: EMBL:BX649148 xref: EMBL:CR627439 xref: EMBL:CR627446 xref: HGNC:HGNC:29093 xref: UniGene:Hs.532399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005252 ! ZC11A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005954 name: ZCCHC10_human def: "Zinc finger CCHC domain-containing protein 10 gene" [UniProtKB:Q8TBK6] xref: EMBL:AK000101 xref: EMBL:BC005211 xref: EMBL:BC022443 xref: HGNC:HGNC:25954 xref: UniGene:Hs.29700 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006253 ! ZCH10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005955 name: CREBZF_human def: "CREB/ATF bZIP transcription factor gene" [UniProtKB:Q9NS37] synonym: "ZF" EXACT [UniProtKB:Q9NS37] xref: EMBL:AF039942 xref: EMBL:BC060807 xref: EMBL:BC093796 xref: EMBL:BC093798 xref: EMBL:DQ128105 xref: HGNC:HGNC:24905 xref: UniGene:Hs.535319 xref: UniGene:Hs.705539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005710 ! ZHANG_HUMAN relationship: codes_for CCO:B0055815 ! Q0P5U9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005956 name: ZHX1_human def: "Zinc fingers and homeoboxes protein 1 gene" [UniProtKB:Q9UKY1] xref: EMBL:AF106862 xref: EMBL:AF195766 xref: EMBL:BC040481 xref: HGNC:HGNC:12871 xref: UniGene:Hs.612084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005395 ! ZHX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005957 name: ZMIZ2_human def: "Zinc finger MIZ domain-containing protein 2 gene" [UniProtKB:Q8NF64] synonym: "HRIHFB2007" EXACT [UniProtKB:Q8NF64] synonym: "KIAA1886" EXACT [UniProtKB:Q8NF64] synonym: "ZIMP7" EXACT [UniProtKB:Q8NF64] xref: EMBL:AB015330 xref: EMBL:AB067473 xref: EMBL:AC004859 xref: EMBL:AC013436 xref: EMBL:AK090415 xref: EMBL:AL136572 xref: EMBL:AL831933 xref: EMBL:AY426594 xref: EMBL:BC021924 xref: EMBL:BC110435 xref: HGNC:HGNC:22229 xref: UniGene:Hs.600681 xref: UniGene:Hs.77978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005218 ! ZMIZ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005958 name: ZNF263_human def: "Zinc finger protein 263 gene" [UniProtKB:O14978] synonym: "FPM315" EXACT [UniProtKB:O14978] synonym: "ZKSCAN12" EXACT [UniProtKB:O14978] xref: EMBL:AC004232 xref: EMBL:BC008805 xref: EMBL:D88827 xref: HGNC:HGNC:13056 xref: UniGene:Hs.611475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005297 ! ZN263_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005959 name: RCHY1_human def: "RING finger and CHY zinc finger domain-containing protein 1 gene" [UniProtKB:Q96PM5] synonym: "ARNIP" EXACT [UniProtKB:Q96PM5] synonym: "CHIMP" EXACT [UniProtKB:Q96PM5] synonym: "PIRH2" EXACT [UniProtKB:Q96PM5] synonym: "RNF199" EXACT [UniProtKB:Q96PM5] synonym: "ZNF363" EXACT [UniProtKB:Q96PM5] xref: EMBL:AF247041 xref: EMBL:AF255666 xref: EMBL:AF305424 xref: HGNC:HGNC:17479 xref: UniGene:Hs.48297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005980 ! ZN363_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005960 name: ZNF443_human def: "Zinc finger protein 443 gene" [UniProtKB:Q9Y2A4] xref: EMBL:AB011414 xref: EMBL:BC032753 xref: HGNC:HGNC:20878 xref: UniGene:Hs.631623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006014 ! ZN443_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005961 name: ZNF451_human def: "Zinc finger protein 451 gene" [UniProtKB:Q9Y4E5] synonym: "COASTER" EXACT [UniProtKB:Q9Y4E5] synonym: "KIAA0576" EXACT [UniProtKB:Q9Y4E5] synonym: "KIAA1702" EXACT [UniProtKB:Q9Y4E5] xref: EMBL:AB011148 xref: EMBL:AB051489 xref: EMBL:AL136311 xref: EMBL:AL450489 xref: EMBL:AY055204 xref: EMBL:BC021712 xref: EMBL:BC042450 xref: EMBL:BC058853 xref: HGNC:HGNC:21091 xref: UniGene:Hs.485628 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005308 ! ZN451_HUMAN relationship: codes_for CCO:B0005597 ! Q5VVE9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005962 name: ZNF521_human def: "Zinc finger protein 521 gene" [UniProtKB:Q96K83] synonym: "EHZF" EXACT [UniProtKB:Q96K83] synonym: "LIP3" EXACT [UniProtKB:Q96K83] xref: EMBL:AF141339 xref: EMBL:AJ518106 xref: EMBL:AK021452 xref: EMBL:AK027354 xref: EMBL:AK074046 xref: EMBL:AL117615 xref: EMBL:BC113622 xref: EMBL:BC113648 xref: EMBL:DQ845345 xref: HGNC:HGNC:24605 xref: UniGene:Hs.116935 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058256 ! ZN521_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005963 name: ZNF567_human def: "Zinc finger protein 567 gene" [UniProtKB:Q8N184] xref: EMBL:BC033849 xref: EMBL:BX640706 xref: HGNC:HGNC:28696 xref: UniGene:Hs.412517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005263 ! ZN567_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005964 name: ZNF580_human def: "Zinc finger protein 580 gene" [UniProtKB:Q9UK33] xref: EMBL:AF184939 xref: EMBL:AL359054 xref: EMBL:BC017698 xref: HGNC:HGNC:29473 xref: UniGene:Hs.631551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005228 ! ZN580_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005965 name: ZNF581_human def: "Zinc finger protein 581 gene" [UniProtKB:Q9P0T4] synonym: "HSPC189" EXACT [UniProtKB:Q9P0T4] xref: EMBL:AF151023 xref: EMBL:BC001219 xref: EMBL:BC010097 xref: EMBL:BC071620 xref: EMBL:BC071845 xref: HGNC:HGNC:25017 xref: UniGene:Hs.20768 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005214 ! ZN581_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005966 name: ZNF655_human def: "Zinc finger protein 655 gene" [UniProtKB:Q8N720] synonym: "VIK" EXACT [UniProtKB:Q8N720] xref: EMBL:AC005020 xref: EMBL:AY099353 xref: EMBL:BC000823 xref: EMBL:BC004288 xref: EMBL:BC007378 xref: EMBL:BC011816 xref: EMBL:BC024770 xref: EMBL:BC037407 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: HGNC:HGNC:30899 xref: UniGene:Hs.696221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005578 ! ZN655_HUMAN relationship: codes_for CCO:B0058476 ! Q9BQ85_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005967 name: ZNF764_human def: "Zinc finger protein 764 gene" [UniProtKB:Q96H86] xref: EMBL:AC002310 xref: EMBL:BC000016 xref: EMBL:BC008821 xref: HGNC:HGNC:28200 xref: UniGene:Hs.132227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005276 ! ZN764_HUMAN relationship: codes_for CCO:B0054140 ! A8MZF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005968 name: ZNF24_human def: "Zinc finger protein 24 gene" [UniProtKB:P17028] synonym: "KOX17" EXACT [UniProtKB:P17028] synonym: "ZNF191" EXACT [UniProtKB:P17028] synonym: "ZSCAN3" EXACT [UniProtKB:P17028] xref: EMBL:AC116447 xref: EMBL:AF016052 xref: EMBL:AF038964 xref: EMBL:BC003566 xref: EMBL:BC016801 xref: EMBL:U68536 xref: EMBL:X52348 xref: HGNC:HGNC:13032 xref: UniGene:Hs.591057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006085 ! ZNF24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005969 name: ZNF7_human def: "Zinc finger protein 7 gene" [UniProtKB:P17097] synonym: "KOX4" EXACT [UniProtKB:P17097] xref: EMBL:AK096025 xref: EMBL:BC058923 xref: EMBL:CH471162 xref: EMBL:M29580 xref: EMBL:X52335 xref: HGNC:HGNC:13139 xref: UniGene:Hs.493218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006254 ! ZNF7_HUMAN relationship: codes_for CCO:B0057527 ! Q8N8Y4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005970 name: ZNHIT1_human def: "Zinc finger HIT domain-containing protein 1 gene" [UniProtKB:O43257] synonym: "CGBP1" EXACT [UniProtKB:O43257] synonym: "ZNFN4A1" EXACT [UniProtKB:O43257] xref: EMBL:AC004876 xref: EMBL:AF093571 xref: EMBL:BC017333 xref: EMBL:U61837 xref: HGNC:HGNC:21688 xref: UniGene:Hs.211079 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005362 ! ZNHI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005972 name: TJP1_human def: "Tight junction protein ZO-1 gene" [UniProtKB:Q07157] synonym: "ZO1" EXACT [UniProtKB:Q07157] xref: EMBL:BC111712 xref: EMBL:DQ015919 xref: EMBL:L14837 xref: HGNC:HGNC:11827 xref: UniGene:Hs.510833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005330 ! ZO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005973 name: ZW10_human def: "Centromere/kinetochore protein zw10 homolog gene" [UniProtKB:O43264] xref: EMBL:U54996 xref: HGNC:HGNC:13194 xref: UniGene:Hs.503886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001387 ! ZW10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005975 name: ZWINT_human def: "ZW10 interactor gene" [UniProtKB:O95229] xref: EMBL:AF067656 xref: EMBL:BC000411 xref: EMBL:BC020979 xref: EMBL:BC110399 xref: HGNC:HGNC:13195 xref: UniGene:Hs.591363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001449 ! ZWINT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005976 name: ZYX_human def: "Zyxin gene" [UniProtKB:Q15942] xref: EMBL:AC092214 xref: EMBL:BC008743 xref: EMBL:BC009360 xref: EMBL:BC010031 xref: EMBL:CR457431 xref: EMBL:X94991 xref: EMBL:X95735 xref: HGNC:HGNC:13200 xref: UniGene:Hs.490415 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005704 ! ZYX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005977 name: ZZEF1_human def: "Zinc finger ZZ-type and EF-hand domain-containing protein 1 gene" [UniProtKB:O43149] synonym: "KIAA0399" EXACT [UniProtKB:O43149] xref: EMBL:AB007859 xref: EMBL:AK001683 xref: EMBL:AK127482 xref: EMBL:AK128386 xref: EMBL:BC067099 xref: HGNC:HGNC:29027 xref: UniGene:Hs.277624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001380 ! ZZEF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005978 name: LOC392884_human def: "Similar to cell division cycle 10 homolog gene" [UniProtKB:A4D1Y2] synonym: "tcag7.1317" EXACT [UniProtKB:A4D1Y2] xref: EMBL:CH236951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001318 ! A4D1Y2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005983 name: EED_human def: "Polycomb protein EED gene" [UniProtKB:O75530] xref: EMBL:AF070418 xref: EMBL:AF078933 xref: EMBL:AF080227 xref: EMBL:AF099032 xref: EMBL:AK292120 xref: EMBL:AP003084 xref: EMBL:BC047672 xref: EMBL:BC068995 xref: EMBL:CH471076 xref: EMBL:U90651 xref: HGNC:HGNC:3188 xref: UniGene:Hs.503510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043864 ! EED_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005984 name: PPP1R15A_human def: "Protein phosphatase 1 regulatory subunit 15A gene" [UniProtKB:O75807] synonym: "GADD34" EXACT [UniProtKB:O75807] xref: EMBL:AK001361 xref: EMBL:BC003067 xref: EMBL:CH471177 xref: EMBL:CR457259 xref: EMBL:U83981 xref: HGNC:HGNC:14375 xref: UniGene:Hs.631593 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001436 ! PR15A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005985 name: APC2_human def: "Adenomatous polyposis coli protein 2 gene" [UniProtKB:O95996] synonym: "APCL" EXACT [UniProtKB:O95996] xref: EMBL:AB012162 xref: EMBL:AB022529 xref: EMBL:AF110334 xref: EMBL:AF110335 xref: EMBL:AF110336 xref: EMBL:AF110337 xref: EMBL:AF128222 xref: EMBL:AJ012652 xref: EMBL:AJ131187 xref: EMBL:BC032573 xref: EMBL:CH471139 xref: HGNC:HGNC:24036 xref: UniGene:Hs.446376 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031540 ! APC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005986 name: C20orf69_human def: "Putative uncharacterized protein C20orf69 gene" [UniProtKB:Q0VF47] xref: EMBL:AL137028 xref: EMBL:BC118988 xref: EMBL:BC122537 xref: HGNC:HGNC:16202 xref: UniGene:Hs.473317 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001729 ! CT069_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005988 name: QSCN6_human def: "Bone-derived growth factor gene" [UniProtKB:Q13876] synonym: "BPGF-1" EXACT [UniProtKB:Q13876] xref: EMBL:L42379 xref: HGNC:HGNC:9756 xref: UniGene:Hs.518374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001768 ! Q13876_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005989 name: orf 2_human def: "Orf 2 protein gene" [UniProtKB:Q15354] synonym: "LL22NC03-10C3.2-002" EXACT [UniProtKB:Q15354] synonym: "PDGFB" EXACT [UniProtKB:Q15354] xref: EMBL:X83705 xref: EMBL:Z81010 xref: HGNC:HGNC:8800 xref: UniGene:Hs.1976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001805 ! Q15354_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005990 name: G1 phase-specific gene_human def: "G1 phase-specific gene" [UniProtKB:Q16164] xref: EMBL:S70622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001815 ! Q16164_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005992 name: PTD004_human def: "Putative uncharacterized protein PTD004 gene" [UniProtKB:Q53SQ6] xref: EMBL:AC016737 xref: HGNC:HGNC:28833 xref: UniGene:Hs.157351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006293 ! Q53SQ6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005997 name: RP11-787I22.2-003_human def: "p53 regulated PA26 nuclear protein (PA26-T1) gene" [UniProtKB:Q5T317] xref: EMBL:AL390208 xref: HGNC:HGNC:21595 xref: UniGene:Hs.591336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001872 ! Q5T317_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0005999 name: BMI1_human def: "Polycomb complex protein BMI-1 gene" [UniProtKB:P35226] synonym: "PCGF4" EXACT [UniProtKB:P35226] synonym: "RNF51" EXACT [UniProtKB:P35226] xref: EMBL:AL158211 xref: EMBL:BC011652 xref: EMBL:L13689 xref: EMBL:S62198 xref: HGNC:HGNC:1066 xref: UniGene:Hs.496613 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006124 ! Q5T8Z1_HUMAN relationship: codes_for CCO:B0055279 ! BMI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006000 name: FAM107B_human def: "Family with sequence similarity 107, member B gene" [UniProtKB:Q5T9K6] synonym: "RP11-153L18.1-005" EXACT [UniProtKB:Q5T9K6] xref: EMBL:AL157706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006355 ! Q5T9K6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006001 name: PDE4DIP_human def: "Phosphodiesterase 4D interacting protein (Myomegalin) gene" [UniProtKB:Q5TB27] synonym: "RP4-791M13.2-009" EXACT [UniProtKB:Q5TB27] xref: EMBL:AL138791 xref: HGNC:HGNC:15580 xref: UniGene:Hs.584841 xref: UniGene:Hs.613082 xref: UniGene:Hs.654651 xref: UniGene:Hs.657490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005975 ! Q5TB27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006002 name: RP3-330M21.2_human def: "Novel protein (P53-associated parkin-like cytoplasmic protein, isoform CRA_a) gene" [UniProtKB:Q5TCY3] synonym: "hCG_1818381" EXACT [UniProtKB:Q5TCY3] synonym: "PARC" EXACT [UniProtKB:Q5TCY3] synonym: "RP3-330M21.2-001" EXACT [UniProtKB:Q5TCY3] xref: EMBL:AL133375 xref: EMBL:CH471081 xref: UniGene:Hs.485434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001888 ! Q5TCY3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006003 name: RP11-291L22.2-003_human def: "Septin gene" [UniProtKB:Q5W161] xref: EMBL:AL133216 xref: UniGene:Hs.406568 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001901 ! Q5W161_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006004 name: KLHLX_human def: "KLEIP (Kelch-like ECT2 interacting protein) gene" [UniProtKB:Q5ZF45] xref: EMBL:AJ844466 xref: HGNC:HGNC:25056 xref: UniGene:Hs.495035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006170 ! Q5ZF45_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006005 name: C9orf78_human def: "Hepatocellular carcinoma-associated antigen 59 gene" [UniProtKB:Q6GVN4] xref: EMBL:AY632862 xref: HGNC:HGNC:24932 xref: UniGene:Hs.278429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006238 ! Q6GVN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006006 name: RNPC4_human def: "RNPC4 protein gene" [UniProtKB:Q6IA98] xref: EMBL:CR457257 xref: HGNC:HGNC:20155 xref: UniGene:Hs.4997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006106 ! Q6IA98_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006007 name: TM4SF6_human def: "TM4SF6 protein gene" [UniProtKB:Q6IAN9] synonym: "hCG_19468" EXACT [UniProtKB:Q6IAN9] synonym: "TSPAN6" EXACT [UniProtKB:Q6IAN9] xref: EMBL:CH471115 xref: EMBL:CR457115 xref: HGNC:HGNC:11858 xref: UniGene:Hs.43233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006247 ! Q6IAN9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006008 name: ARHH_human def: "ARHH protein (Ras homolog gene family, member H, isoform CRA_a) (cDNA, FLJ94345, Homo sapiens ras homolog gene family, member H (ARHH), mRNA) gene" [UniProtKB:Q6ICP4] synonym: "hCG_37394" EXACT [UniProtKB:Q6ICP4] synonym: "RHOH" EXACT [UniProtKB:Q6ICP4] xref: EMBL:AK313744 xref: EMBL:CH471069 xref: EMBL:CR450349 xref: HGNC:HGNC:686 xref: UniGene:Hs.654594 xref: UniGene:Hs.694951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006171 ! Q6ICP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006009 name: LOC441601_human def: "Septin gene" [UniProtKB:Q6NVV2] xref: EMBL:BC067889 xref: UniGene:Hs.144683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001910 ! Q6NVV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006013 name: RIPK3_human def: "Receptor-interacting serine/threonine-protein kinase 3 gene" [UniProtKB:Q9Y572] synonym: "RIP3" EXACT [UniProtKB:Q9Y572] xref: EMBL:AF156884 xref: EMBL:AY453693 xref: EMBL:AY494982 xref: EMBL:AY494983 xref: EMBL:BC062584 xref: EMBL:CH471078 xref: HGNC:HGNC:10021 xref: UniGene:Hs.268551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059370 ! RIPK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006017 name: IL16_human def: "IL16 protein gene" [UniProtKB:Q8IUU6] xref: EMBL:BC040272 xref: HGNC:HGNC:5980 xref: UniGene:Hs.459095 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005242 ! Q8IUU6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006018 name: ZNF646_human def: "Zinc finger protein 646 gene" [UniProtKB:O15015] synonym: "KIAA0296" EXACT [UniProtKB:O15015] xref: EMBL:AB002294 xref: EMBL:BC035589 xref: EMBL:CH471192 xref: HGNC:HGNC:29004 xref: UniGene:Hs.119273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005230 ! Q8IVD8_HUMAN relationship: codes_for CCO:B0054398 ! ZN646_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006019 name: ATXN7L3_human def: "Ataxin-7-like protein 3. gene" [UniProtKB:Q8IY68] xref: EMBL:BC037418 xref: HGNC:HGNC:25416 xref: UniGene:Hs.512651 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005946 ! Q8IY68_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006020 name: SEPT12_human def: "Septin-12 gene" [UniProtKB:Q8IYM1] xref: EMBL:AK058139 xref: EMBL:BC024017 xref: EMBL:BC035619 xref: EMBL:CH471112 xref: EMBL:DQ456996 xref: EMBL:DQ517531 xref: EMBL:EF620906 xref: HGNC:HGNC:26348 xref: UniGene:Hs.126780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026253 ! SEP12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006021 name: MYO15B_human def: "MYO15B protein gene" [UniProtKB:Q8N374] xref: EMBL:BC027875 xref: HGNC:HGNC:14083 xref: UniGene:Hs.390817 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005196 ! Q8N374_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006022 name: TRBV21-1_human def: "TRBV21-1 protein gene" [UniProtKB:Q8N3Z8] xref: EMBL:BC036926 xref: HGNC:HGNC:12198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006251 ! Q8N3Z8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006023 name: ZWILCH_human def: "Protein zwilch homolog gene" [UniProtKB:Q9H900] xref: EMBL:AK000898 xref: EMBL:AK023175 xref: EMBL:AK027468 xref: EMBL:BC036900 xref: EMBL:BC090041 xref: EMBL:BX640701 xref: EMBL:CH471082 xref: HGNC:HGNC:25468 xref: UniGene:Hs.21331 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032821 ! ZWILC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006024 name: IKZF3_human def: "Zinc finger protein Aiolos gene" [UniProtKB:Q9UKT9] synonym: "ZNFN1A3" EXACT [UniProtKB:Q9UKT9] xref: EMBL:AF129512 xref: EMBL:AJ292565 xref: EMBL:AJ292566 xref: EMBL:AJ292567 xref: EMBL:AJ292568 xref: EMBL:AJ292569 xref: EMBL:BC032707 xref: EMBL:CH471152 xref: HGNC:HGNC:13178 xref: UniGene:Hs.444388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038370 ! IKZF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006025 name: JMY_human def: "Junction-mediating and -regulatory protein gene" [UniProtKB:Q8N9B5] xref: EMBL:AC016559 xref: EMBL:AC020898 xref: EMBL:AK095189 xref: EMBL:BC130624 xref: EMBL:CH471084 xref: UniGene:Hs.482605 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040022 ! JMY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006026 name: DKFZp586M1819_human def: "Putative uncharacterized protein DKFZp586M1819 gene" [UniProtKB:Q8NDD3] xref: EMBL:AL834255 xref: HGNC:HGNC:20880 xref: UniGene:Hs.355753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005953 ! Q8NDD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006027 name: OK/SW-cl.16_human def: "OK/SW-CL.16 gene" [UniProtKB:Q8NI70] xref: EMBL:AB064665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005408 ! Q8NI70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006028 name: RHEBL1_human def: "GTPase RhebL1 precursor gene" [UniProtKB:Q8TAI7] xref: EMBL:AK098663 xref: EMBL:AY327412 xref: EMBL:AY509932 xref: EMBL:BC027482 xref: EMBL:CH471111 xref: HGNC:HGNC:21166 xref: UniGene:Hs.159013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040684 ! REBL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006029 name: AFF4_human def: "AF4/FMR2 family member 4 gene" [UniProtKB:Q9UHB7] synonym: "AF5Q31" EXACT [UniProtKB:Q9UHB7] synonym: "HSPC092" EXACT [UniProtKB:Q9UHB7] synonym: "MCEF" EXACT [UniProtKB:Q9UHB7] xref: EMBL:AB209547 xref: EMBL:AF161355 xref: EMBL:AF197927 xref: EMBL:AF213987 xref: EMBL:BC025700 xref: EMBL:BC063007 xref: EMBL:BC100287 xref: HGNC:HGNC:17869 xref: UniGene:Hs.519313 xref: UniGene:Hs.664840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005236 ! Q8TAX5_HUMAN relationship: codes_for CCO:B0059133 ! AFF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006030 name: PAK7_human def: "Serine/threonine-protein kinase PAK 7 gene" [UniProtKB:Q9P286] synonym: "KIAA1264" EXACT [UniProtKB:Q9P286] synonym: "PAK5" EXACT [UniProtKB:Q9P286] xref: EMBL:AB033090 xref: EMBL:AB040812 xref: EMBL:AL031652 xref: EMBL:AL135935 xref: EMBL:AL353612 xref: EMBL:BC024179 xref: HGNC:HGNC:15916 xref: UniGene:Hs.32539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005193 ! Q8TB93_HUMAN relationship: codes_for CCO:B0059054 ! PAK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006032 name: ANKRD24_human def: "Ankyrin repeat domain-containing protein 24 gene" [UniProtKB:Q8TF21] synonym: "KIAA1981" EXACT [UniProtKB:Q8TF21] xref: EMBL:AB075861 xref: EMBL:AC005578 xref: EMBL:AC006930 xref: HGNC:HGNC:29424 xref: UniGene:Hs.197872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040685 ! ANR24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006034 name: ZNF446_human def: "Zinc finger protein 446 gene" [UniProtKB:Q9NWS9] synonym: "ZKSCAN20" EXACT [UniProtKB:Q9NWS9] xref: EMBL:AK000633 xref: EMBL:AY280800 xref: EMBL:BC017206 xref: HGNC:HGNC:21036 xref: UniGene:Hs.697107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005269 ! Q96AF5_HUMAN relationship: codes_for CCO:B0038152 ! ZN446_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006035 name: ATF4_human def: "Cyclic AMP-dependent transcription factor ATF-4 gene" [UniProtKB:P18848] synonym: "TXREB" EXACT [UniProtKB:P18848] xref: EMBL:AL022312 xref: EMBL:BC008090 xref: EMBL:BC011994 xref: EMBL:BC016855 xref: EMBL:BC022088 xref: EMBL:BC024775 xref: EMBL:BC044895 xref: EMBL:BC073754 xref: EMBL:BC073990 xref: EMBL:CH471095 xref: EMBL:CR456384 xref: EMBL:D90209 xref: EMBL:M86842 xref: HGNC:HGNC:786 xref: UniGene:Hs.496487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005172 ! Q96AQ3_HUMAN relationship: codes_for CCO:B0021435 ! ATF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006036 name: C8orf30A_human def: "C8orf30A protein gene" [UniProtKB:Q96BK8] xref: EMBL:BC015471 xref: HGNC:HGNC:24161 xref: UniGene:Hs.300224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006094 ! Q96BK8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006037 name: CUTC_human def: "Copper homeostasis protein cutC homolog gene" [UniProtKB:Q9NTM9] synonym: "CGI-32" EXACT [UniProtKB:Q9NTM9] xref: EMBL:AF132966 xref: EMBL:BC015059 xref: EMBL:BC021105 xref: EMBL:BC028948 xref: HGNC:HGNC:24271 xref: UniGene:Hs.16606 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005203 ! Q96BX3_HUMAN relationship: codes_for CCO:B0026108 ! CUTC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006038 name: POM121_human def: "Nuclear envelope pore membrane protein POM 121 gene" [UniProtKB:Q96HA1] synonym: "KIAA0618" EXACT [UniProtKB:Q96HA1] synonym: "NUP121" EXACT [UniProtKB:Q96HA1] synonym: "POM121A" EXACT [UniProtKB:Q96HA1] xref: EMBL:AB014518 xref: EMBL:AB289621 xref: EMBL:AC005488 xref: EMBL:AK022555 xref: EMBL:AK292548 xref: EMBL:AL080109 xref: EMBL:AL713666 xref: EMBL:BC001518 xref: EMBL:BC008794 xref: HGNC:HGNC:19702 xref: UniGene:Hs.655217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061984 ! P121A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006039 name: JUB_human def: "Protein ajuba gene" [UniProtKB:Q96IF1] xref: EMBL:AY169959 xref: EMBL:BC007580 xref: EMBL:BC034968 xref: EMBL:CH471078 xref: HGNC:HGNC:20250 xref: UniGene:Hs.655832 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026254 ! JUB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006040 name: hCG_2002594_human def: "Septin gene" [UniProtKB:Q96MY5] xref: EMBL:AK056273 xref: EMBL:CH471176 xref: HGNC:HGNC:9164 xref: UniGene:Hs.283743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002050 ! Q96MY5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006041 name: NAP1L5_human def: "Nucleosome assembly protein 1-like 5 gene" [UniProtKB:Q96NT1] xref: EMBL:AK054689 xref: EMBL:BC104883 xref: EMBL:CH471057 xref: HGNC:HGNC:19968 xref: UniGene:Hs.12554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063386 ! NP1L5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006042 name: CE5B3 alpha_human def: "Bradeion alpha gene" [UniProtKB:Q96Q97] xref: EMBL:AB002110 xref: HGNC:HGNC:9165 xref: UniGene:Hs.287518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002057 ! Q96Q97_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006044 name: X-1_human def: "X-1 protein gene" [UniProtKB:Q99539] xref: EMBL:X98266 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002068 ! Q99539_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006046 name: TUBGCP4_human def: "TUBGCP4 protein gene" [UniProtKB:Q9BVR6] xref: EMBL:BC000966 xref: UniGene:Hs.654843 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005189 ! Q9BVR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006047 name: PCBP4_human def: "Poly(RC) binding protein 4, isoform CRA_a gene" [UniProtKB:Q9GZT1] synonym: "hCG_42594" EXACT [UniProtKB:Q9GZT1] xref: EMBL:AF257770 xref: EMBL:AF257772 xref: EMBL:CH471055 xref: HGNC:HGNC:8652 xref: UniGene:Hs.20930 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002121 ! Q9GZT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006048 name: PNUTL2_human def: "Septin gene" [UniProtKB:Q9H315] synonym: "hCG_30696" EXACT [UniProtKB:Q9H315] synonym: "SEPT4" EXACT [UniProtKB:Q9H315] xref: EMBL:AF176379 xref: EMBL:CH471109 xref: HGNC:HGNC:9165 xref: UniGene:Hs.287518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002132 ! Q9H315_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006049 name: KIAA1549_human def: "UPF0606 protein KIAA1549 gene" [UniProtKB:Q9HCM3] xref: EMBL:AB046769 xref: EMBL:AC018663 xref: EMBL:AC083868 xref: EMBL:AC093144 xref: EMBL:AK097963 xref: EMBL:AL136736 xref: EMBL:BC038232 xref: EMBL:BC091523 xref: HGNC:HGNC:22219 xref: UniGene:Hs.605380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043861 ! K1549_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006050 name: PDGFC_human def: "Platelet-derived growth factor C precursor gene" [UniProtKB:Q9NRA1] synonym: "SCDGF" EXACT [UniProtKB:Q9NRA1] synonym: "UNQ174/PRO200" EXACT [UniProtKB:Q9NRA1] xref: EMBL:AB033831 xref: EMBL:AC092608 xref: EMBL:AC093325 xref: EMBL:AF091434 xref: EMBL:AF244813 xref: EMBL:AF260738 xref: EMBL:AY358493 xref: EMBL:CH471056 xref: HGNC:HGNC:8801 xref: UniGene:Hs.570855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002158 ! PDGFC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006052 name: RPRM_human def: "Protein reprimo gene" [UniProtKB:Q9NS64] xref: EMBL:AB043585 xref: EMBL:AC012501 xref: EMBL:BC002908 xref: EMBL:CH471058 xref: HGNC:HGNC:24201 xref: UniGene:Hs.100890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026256 ! RPRM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006053 name: KIF15_human def: "Kinesin-like protein KIF15 gene" [UniProtKB:Q9NS87] synonym: "KLP2" EXACT [UniProtKB:Q9NS87] synonym: "KNSL7" EXACT [UniProtKB:Q9NS87] xref: EMBL:AB035898 xref: EMBL:AF308294 xref: EMBL:AK027816 xref: EMBL:AL832908 xref: EMBL:BC117174 xref: HGNC:HGNC:17273 xref: UniGene:Hs.658939 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002165 ! KIF15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006054 name: DKFZp547B243_human def: "Septin gene" [UniProtKB:Q9NSH2] xref: EMBL:AL353938 xref: HGNC:HGNC:14349 xref: UniGene:Hs.469615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002166 ! Q9NSH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006055 name: IQWD1_human def: "PC326 protein gene" [UniProtKB:Q9P0U0] synonym: "PC326" EXACT [UniProtKB:Q9P0U0] xref: EMBL:AF150734 xref: HGNC:HGNC:30002 xref: UniGene:Hs.435741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006353 ! Q9P0U0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006056 name: MCTS1_human def: "Malignant T cell amplified sequence 1 gene" [UniProtKB:Q9ULC4] synonym: "MCT1" EXACT [UniProtKB:Q9ULC4] xref: EMBL:AB034206 xref: EMBL:AK311993 xref: EMBL:AY364258 xref: EMBL:BC001013 xref: EMBL:BC095461 xref: EMBL:CH471107 xref: HGNC:HGNC:23357 xref: UniGene:Hs.102696 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002223 ! MCTS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006344 name: AGRN_human def: "Agrin precursor gene" [UniProtKB:O00468] synonym: "AGRIN" EXACT [UniProtKB:O00468] xref: EMBL:AB191264 xref: EMBL:AF016903 xref: EMBL:AL645608 xref: EMBL:BC004220 xref: EMBL:BC007649 xref: EMBL:BC034009 xref: EMBL:BC063620 xref: EMBL:U84406 xref: HGNC:HGNC:329 xref: UniGene:Hs.273330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005949 ! AGRIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006345 name: AKTIP_human def: "AKT-interacting protein gene" [UniProtKB:Q9H8T0] synonym: "FTS" EXACT [UniProtKB:Q9H8T0] xref: EMBL:AK023320 xref: EMBL:BC001134 xref: EMBL:BC095401 xref: EMBL:CR457308 xref: HGNC:HGNC:16710 xref: UniGene:Hs.380897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026276 ! AKTIP_HUMAN relationship: codes_for CCO:B0056340 ! Q503B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006346 name: CALCOCO2_human def: "Calcium-binding and coiled-coil domain-containing protein 2 gene" [UniProtKB:Q13137] synonym: "NDP52" EXACT [UniProtKB:Q13137] xref: EMBL:AK222666 xref: EMBL:AK223227 xref: EMBL:BC004130 xref: EMBL:BC015893 xref: EMBL:CH471109 xref: EMBL:CR456763 xref: EMBL:U22897 xref: HGNC:HGNC:29912 xref: UniGene:Hs.514920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026268 ! CACO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006348 name: HSD17B14_human def: "17-beta-hydroxysteroid dehydrogenase 14 gene" [UniProtKB:Q9BPX1] synonym: "DHRS10" EXACT [UniProtKB:Q9BPX1] synonym: "SDR3" EXACT [UniProtKB:Q9BPX1] synonym: "UNQ502/PRO474" EXACT [UniProtKB:Q9BPX1] xref: EMBL:AF126781 xref: EMBL:AY358430 xref: EMBL:BC006283 xref: EMBL:BC006294 xref: HGNC:HGNC:23238 xref: UniGene:Hs.18788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026267 ! DHB14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006349 name: EIF3B_human def: "Eukaryotic translation initiation factor 3 subunit B gene" [UniProtKB:P55884] synonym: "EIF3S9" EXACT [UniProtKB:P55884] xref: EMBL:BC001173 xref: EMBL:BC110865 xref: EMBL:U62583 xref: EMBL:U78525 xref: HGNC:HGNC:3280 xref: UniGene:Hs.371001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026275 ! EIF3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006350 name: EIF3C_human def: "Eukaryotic translation initiation factor 3 subunit C gene" [UniProtKB:Q99613] synonym: "EIF3S8" EXACT [UniProtKB:Q99613] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026271 ! EIF3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006351 name: EIF3D_human def: "Eukaryotic translation initiation factor 3 subunit D gene" [UniProtKB:O15371] synonym: "EIF3S7" EXACT [UniProtKB:O15371] xref: EMBL:AL022313 xref: EMBL:BC000328 xref: EMBL:BC000469 xref: EMBL:BC014912 xref: EMBL:BC080515 xref: EMBL:BC093100 xref: EMBL:BC093686 xref: EMBL:BC101477 xref: EMBL:BT007381 xref: EMBL:CR456489 xref: EMBL:U54558 xref: HGNC:HGNC:3278 xref: UniGene:Hs.55682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026270 ! EIF3D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006352 name: EIF3E_human def: "Eukaryotic translation initiation factor 3 subunit E gene" [UniProtKB:P60228] synonym: "EIF3S6" EXACT [UniProtKB:P60228] synonym: "INT6" EXACT [UniProtKB:P60228] xref: EMBL:BC000734 xref: EMBL:BC008419 xref: EMBL:BC016706 xref: EMBL:BC017887 xref: EMBL:BC021679 xref: EMBL:U54562 xref: EMBL:U62962 xref: EMBL:U85947 xref: EMBL:U94162 xref: EMBL:U94163 xref: EMBL:U94164 xref: EMBL:U94165 xref: EMBL:U94166 xref: EMBL:U94167 xref: EMBL:U94168 xref: EMBL:U94169 xref: EMBL:U94170 xref: EMBL:U94171 xref: EMBL:U94172 xref: EMBL:U94173 xref: EMBL:U94174 xref: EMBL:U94175 xref: HGNC:HGNC:3277 xref: UniGene:Hs.405590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026272 ! EIF3E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006353 name: EIF3F_human def: "Eukaryotic translation initiation factor 3 subunit F gene" [UniProtKB:O00303] synonym: "EIF3S5" EXACT [UniProtKB:O00303] xref: EMBL:AK095574 xref: EMBL:BC000490 xref: EMBL:BT006894 xref: EMBL:CR456959 xref: EMBL:U94855 xref: HGNC:HGNC:3275 xref: UniGene:Hs.516023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026277 ! EIF3F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006354 name: EIF3G_human def: "Eukaryotic translation initiation factor 3 subunit G gene" [UniProtKB:O75821] synonym: "EIF3S4" EXACT [UniProtKB:O75821] xref: EMBL:AF020833 xref: EMBL:AF092453 xref: EMBL:AF094850 xref: EMBL:BC000733 xref: EMBL:BC008469 xref: EMBL:BT006889 xref: EMBL:U96074 xref: HGNC:HGNC:3274 xref: UniGene:Hs.529059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026269 ! EIF3G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006355 name: EIF3I_human def: "Eukaryotic translation initiation factor 3 subunit I gene" [UniProtKB:Q13347] synonym: "EIF3S2" EXACT [UniProtKB:Q13347] synonym: "TRIP1" EXACT [UniProtKB:Q13347] xref: EMBL:BC000413 xref: EMBL:BC003140 xref: EMBL:U36764 xref: EMBL:U39067 xref: HGNC:HGNC:3272 xref: UniGene:Hs.530096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026273 ! EIF3I_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006356 name: EIF3J_human def: "Eukaryotic translation initiation factor 3 subunit J gene" [UniProtKB:O75822] synonym: "EIF3S1" EXACT [UniProtKB:O75822] synonym: "PRO0391" EXACT [UniProtKB:O75822] xref: EMBL:AF090923 xref: EMBL:AK023388 xref: EMBL:BC002719 xref: EMBL:U97670 xref: HGNC:HGNC:3270 xref: UniGene:Hs.404056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026278 ! EIF3J_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006357 name: EIF3K_human def: "Eukaryotic translation initiation factor 3 subunit K gene" [UniProtKB:Q9UBQ5] synonym: "ARG134" EXACT [UniProtKB:Q9UBQ5] synonym: "EIF3S12" EXACT [UniProtKB:Q9UBQ5] synonym: "HSPC029" EXACT [UniProtKB:Q9UBQ5] synonym: "MSTP001" EXACT [UniProtKB:Q9UBQ5] synonym: "PTD001" EXACT [UniProtKB:Q9UBQ5] xref: EMBL:AB019392 xref: EMBL:AF077051 xref: EMBL:AF085358 xref: EMBL:AF109355 xref: EMBL:AF315506 xref: EMBL:AY245432 xref: EMBL:BC001031 xref: EMBL:BC007335 xref: EMBL:BC007559 xref: HGNC:HGNC:24656 xref: UniGene:Hs.314359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026274 ! EIF3K_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006358 name: ERCC2_human def: "TFIIH basal transcription factor complex helicase subunit gene" [UniProtKB:P18074] synonym: "XPD" EXACT [UniProtKB:P18074] synonym: "XPDC" EXACT [UniProtKB:P18074] xref: EMBL:AY092780 xref: EMBL:BC108255 xref: EMBL:L47234 xref: EMBL:X52221 xref: EMBL:X52222 xref: HGNC:HGNC:3434 xref: UniGene:Hs.487294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026248 ! ERCC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006359 name: HNF1A_human def: "Hepatocyte nuclear factor 1-alpha gene" [UniProtKB:P20823] synonym: "TCF1" EXACT [UniProtKB:P20823] xref: EMBL:BC104908 xref: EMBL:BC104910 xref: EMBL:M57732 xref: EMBL:U72612 xref: EMBL:U72613 xref: EMBL:U72614 xref: EMBL:U72615 xref: EMBL:U72616 xref: EMBL:U72617 xref: EMBL:U72618 xref: EMBL:X71346 xref: HGNC:HGNC:11621 xref: UniGene:Hs.654455 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006008 ! HNF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006360 name: HNRNPC_human def: "Heterogeneous nuclear ribonucleoproteins C1/C2 gene" [UniProtKB:P07910] synonym: "HNRPC" EXACT [UniProtKB:P07910] xref: EMBL:AB209527 xref: EMBL:AK223517 xref: EMBL:BC003394 xref: EMBL:BC007052 xref: EMBL:BC008364 xref: EMBL:BC008423 xref: EMBL:BC066932 xref: EMBL:BC089438 xref: EMBL:BC103758 xref: EMBL:BC108658 xref: EMBL:BX161480 xref: EMBL:BX247961 xref: EMBL:BX247992 xref: EMBL:M16342 xref: EMBL:M29063 xref: HGNC:HGNC:5035 xref: UniGene:Hs.449114 xref: UniGene:Hs.508848 xref: UniGene:Hs.701780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005239 ! HNRPC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006361 name: HNRNPL_human def: "Heterogeneous nuclear ribonucleoprotein L gene" [UniProtKB:P14866] synonym: "HNRPL" EXACT [UniProtKB:P14866] synonym: "P/OKcl.14" EXACT [UniProtKB:P14866] xref: EMBL:AB044547 xref: EMBL:AC008982 xref: EMBL:CH471126 xref: EMBL:X16135 xref: HGNC:HGNC:5045 xref: UniGene:Hs.654559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006275 ! HNRPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006362 name: EIF3EIP_human def: "Eukaryotic translation initiation factor 3 subunit E-interacting protein gene" [UniProtKB:Q9Y262] synonym: "EIF3S6IP" EXACT [UniProtKB:Q9Y262] synonym: "HSPC021" EXACT [UniProtKB:Q9Y262] synonym: "HSPC025" EXACT [UniProtKB:Q9Y262] synonym: "MSTP005" EXACT [UniProtKB:Q9Y262] xref: EMBL:AF077207 xref: EMBL:AF083243 xref: EMBL:AF109359 xref: EMBL:AK222496 xref: EMBL:AK222529 xref: EMBL:AL022311 xref: EMBL:BC001101 xref: EMBL:BC007510 xref: EMBL:BC029265 xref: EMBL:CR456436 xref: EMBL:Z97630 xref: HGNC:HGNC:18138 xref: UniGene:Hs.446852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026279 ! IF3EI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006363 name: KLHDC3_human def: "Kelch domain-containing protein 3 gene" [UniProtKB:Q9BQ90] synonym: "PEAS" EXACT [UniProtKB:Q9BQ90] xref: EMBL:AB055925 xref: EMBL:AL136304 xref: EMBL:BC000295 xref: EMBL:BC001789 xref: EMBL:BC001793 xref: EMBL:BC007296 xref: EMBL:BC021546 xref: HGNC:HGNC:20704 xref: UniGene:Hs.412468 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026255 ! KLDC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006364 name: NOXIN_human def: "Nitric oxide-inducible gene" [UniProtKB:Q8IXT1] synonym: "C11orf82" EXACT [UniProtKB:Q8IXT1] xref: EMBL:AK023998 xref: EMBL:AK058145 xref: EMBL:AP001646 xref: EMBL:BC039268 xref: HGNC:HGNC:26351 xref: UniGene:Hs.165607 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026252 ! NOXIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006365 name: PDS5B_human def: "Sister chromatid cohesion protein PDS5 homolog B gene" [UniProtKB:Q9NTI5] synonym: "APRIN" EXACT [UniProtKB:Q9NTI5] synonym: "AS3" EXACT [UniProtKB:Q9NTI5] synonym: "KIAA0979" EXACT [UniProtKB:Q9NTI5] xref: EMBL:AB023196 xref: EMBL:AK026889 xref: EMBL:AL137201 xref: EMBL:AL138820 xref: EMBL:BC039256 xref: EMBL:BC070274 xref: EMBL:U95825 xref: EMBL:Z75889 xref: HGNC:HGNC:20418 xref: UniGene:Hs.699308 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026257 ! PDS5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006366 name: PIGU_human def: "Phosphatidylinositol glycan anchor biosynthesis class U protein gene" [UniProtKB:Q9H490] synonym: "CDC91L1" EXACT [UniProtKB:Q9H490] synonym: "PSEC0205" EXACT [UniProtKB:Q9H490] synonym: "UNQ3055/PRO9875" EXACT [UniProtKB:Q9H490] xref: EMBL:AB086842 xref: EMBL:AK075507 xref: EMBL:AL118520 xref: EMBL:AY339061 xref: EMBL:AY358816 xref: EMBL:AY422169 xref: EMBL:BC030512 xref: HGNC:HGNC:15791 xref: UniGene:Hs.253319 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002135 ! PIGU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006367 name: PRIM2_human def: "DNA primase large subunit gene" [UniProtKB:P49643] synonym: "PRIM2A" EXACT [UniProtKB:P49643] xref: EMBL:AL121975 xref: EMBL:AL162579 xref: EMBL:BC017833 xref: EMBL:BC064931 xref: EMBL:X74331 xref: HGNC:HGNC:9370 xref: UniGene:Hs.654580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005508 ! PRI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006368 name: HNRNPA1_human def: "Heterogeneous nuclear ribonucleoprotein A1 gene" [UniProtKB:P09651] synonym: "HNRPA1" EXACT [UniProtKB:P09651] xref: EMBL:BC002355 xref: EMBL:BC009600 xref: EMBL:BC012158 xref: EMBL:BC033714 xref: EMBL:BC052296 xref: EMBL:BC070315 xref: EMBL:BC074502 xref: EMBL:BC103707 xref: EMBL:X04347 xref: EMBL:X06747 xref: EMBL:X12671 xref: EMBL:X79536 xref: HGNC:HGNC:5031 xref: UniGene:Hs.699190 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005774 ! ROA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006369 name: HNRNPA2B1_human def: "Heterogeneous nuclear ribonucleoproteins A2/B1 gene" [UniProtKB:P22626] synonym: "HNRPA2B1" EXACT [UniProtKB:P22626] xref: EMBL:AK289429 xref: EMBL:D28877 xref: EMBL:M29064 xref: EMBL:M29065 xref: EMBL:U09120 xref: EMBL:U09121 xref: EMBL:U09122 xref: EMBL:U09123 xref: HGNC:HGNC:5033 xref: UniGene:Hs.487774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005725 ! ROA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006370 name: SPC24_human def: "Kinetochore protein Spc24 gene" [UniProtKB:Q8NBT2] synonym: "SPBC24" EXACT [UniProtKB:Q8NBT2] xref: EMBL:AK075287 xref: EMBL:AY456387 xref: EMBL:BC105037 xref: EMBL:BC105039 xref: HGNC:HGNC:26913 xref: UniGene:Hs.381225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001973 ! SPC24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006371 name: FARSB_human def: "Phenylalanyl-tRNA synthetase beta chain gene" [UniProtKB:Q9NSD9] synonym: "FARSLB" EXACT [UniProtKB:Q9NSD9] synonym: "FRSB" EXACT [UniProtKB:Q9NSD9] synonym: "HSPC173" EXACT [UniProtKB:Q9NSD9] xref: EMBL:AF042346 xref: EMBL:AF161521 xref: EMBL:BC017783 xref: EMBL:D84430 xref: HGNC:HGNC:17800 xref: UniGene:Hs.471452 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005753 ! SYFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006372 name: TCF19_human def: "Transcription factor 19 gene" [UniProtKB:Q9Y242] synonym: "SC1" EXACT [UniProtKB:Q9Y242] xref: EMBL:AB029516 xref: EMBL:AB029517 xref: EMBL:AB029518 xref: EMBL:AB029519 xref: EMBL:AB088113 xref: EMBL:AB103619 xref: EMBL:AB202105 xref: EMBL:AL662833 xref: EMBL:AL662844 xref: EMBL:AL773544 xref: EMBL:BA000025 xref: EMBL:BC002493 xref: EMBL:BC033086 xref: EMBL:BC044632 xref: EMBL:BT007247 xref: EMBL:BX088580 xref: EMBL:CH471081 xref: EMBL:S53374 xref: EMBL:U25826 xref: HGNC:HGNC:11629 xref: UniGene:Hs.584807 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026258 ! TCF19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006373 name: VEGFA_human def: "Vascular endothelial growth factor A precursor gene" [UniProtKB:P15692] synonym: "VEGF" EXACT [UniProtKB:P15692] xref: EMBL:AB021221 xref: EMBL:AF022375 xref: EMBL:AF062645 xref: EMBL:AF091352 xref: EMBL:AF214570 xref: EMBL:AF430806 xref: EMBL:AF437895 xref: EMBL:AF486837 xref: EMBL:AJ010438 xref: EMBL:AL136131 xref: EMBL:AY047581 xref: EMBL:AY766116 xref: EMBL:BC065522 xref: EMBL:DQ229900 xref: EMBL:M27281 xref: EMBL:M32977 xref: EMBL:M63971 xref: EMBL:M63972 xref: EMBL:M63973 xref: EMBL:M63974 xref: EMBL:M63975 xref: EMBL:M63976 xref: EMBL:M63977 xref: EMBL:M63978 xref: EMBL:S85192 xref: EMBL:S85199 xref: EMBL:S85201 xref: EMBL:S85219 xref: EMBL:S85222 xref: EMBL:S85224 xref: EMBL:X62568 xref: HGNC:HGNC:12680 xref: UniGene:Hs.73793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001525 ! VEGFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006374 name: ZMYND11_human def: "Zinc finger MYND domain-containing protein 11 gene" [UniProtKB:Q15326] synonym: "BS69" EXACT [UniProtKB:Q15326] xref: EMBL:AL589988 xref: EMBL:AL603831 xref: EMBL:X86098 xref: HGNC:HGNC:16966 xref: UniGene:Hs.292265 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026249 ! ZMY11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006375 name: NEDD5_human def: "Septin gene" [UniProtKB:Q53QU3] xref: EMBL:AC104841 xref: HGNC:HGNC:7729 xref: UniGene:Hs.335057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023650 ! Q53QU3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006376 name: DKFZp586I031_human def: "Putative uncharacterized protein DKFZp586I031 gene" [UniProtKB:Q5JXL7] xref: EMBL:AL050392 xref: HGNC:HGNC:1717 xref: UniGene:Hs.191346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026250 ! Q5JXL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006377 name: DKFZp434G222_human def: "Putative uncharacterized protein DKFZp434G222 gene" [UniProtKB:Q9UG28] xref: EMBL:AL080206 xref: HGNC:HGNC:11751 xref: UniGene:Hs.379018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024344 ! Q9UG28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006401 name: COPS3_human def: "COP9 signalosome complex subunit 3 gene" [UniProtKB:Q9UNS2] synonym: "CSN3" EXACT [UniProtKB:Q9UNS2] xref: EMBL:AF031647 xref: EMBL:AF098109 xref: EMBL:BC001891 xref: HGNC:HGNC:2239 xref: UniGene:Hs.6076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030750 ! CSN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006402 name: VAMP3_human def: "Vesicle-associated membrane protein 3 gene" [UniProtKB:Q15836] synonym: "SYB3" EXACT [UniProtKB:Q15836] xref: EMBL:BC003570 xref: EMBL:BC007050 xref: EMBL:BT007327 xref: EMBL:U64520 xref: EMBL:Z98884 xref: HGNC:HGNC:12644 xref: UniGene:Hs.66708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030751 ! VAMP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006414 name: MOBKL3_human def: "Mps one binder kinase activator-like 3 gene" [UniProtKB:Q9Y3A3] synonym: "CGI-95" EXACT [UniProtKB:Q9Y3A3] synonym: "MOB3" EXACT [UniProtKB:Q9Y3A3] synonym: "PREI3" EXACT [UniProtKB:Q9Y3A3] xref: EMBL:AB015441 xref: EMBL:AF093825 xref: EMBL:AF151853 xref: EMBL:AF250319 xref: EMBL:AJ580638 xref: EMBL:AK027043 xref: EMBL:AL080070 xref: EMBL:BC005237 xref: EMBL:CR457371 xref: HGNC:HGNC:17261 xref: UniGene:Hs.645458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031198 ! MOBL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006415 name: NDC80_human def: "Kinetochore protein NDC80 homolog gene" [UniProtKB:O14777] synonym: "HEC" EXACT [UniProtKB:O14777] synonym: "HEC1" EXACT [UniProtKB:O14777] synonym: "KNTC2" EXACT [UniProtKB:O14777] xref: EMBL:AF017790 xref: EMBL:BC010171 xref: HGNC:HGNC:16909 xref: UniGene:Hs.414407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001360 ! NDC80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006416 name: UBA3_human def: "NEDD8-activating enzyme E1 catalytic subunit gene" [UniProtKB:Q8TBC4] synonym: "UBE1C" EXACT [UniProtKB:Q8TBC4] xref: EMBL:AB012190 xref: EMBL:AF046024 xref: EMBL:AL117566 xref: EMBL:BC022853 xref: HGNC:HGNC:12470 xref: UniGene:Hs.154320 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001989 ! UBA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006423 name: ASNS_human def: "Asparagine synthetase [glutamine-hydrolyzing] gene" [UniProtKB:P08243] synonym: "TS11" EXACT [UniProtKB:P08243] xref: EMBL:AC079781 xref: EMBL:BC008723 xref: EMBL:BC014621 xref: EMBL:BT007113 xref: EMBL:L35936 xref: EMBL:L35937 xref: EMBL:L35938 xref: EMBL:L35939 xref: EMBL:L35940 xref: EMBL:L35941 xref: EMBL:L35942 xref: EMBL:L35943 xref: EMBL:L35944 xref: EMBL:L35945 xref: EMBL:L35946 xref: EMBL:M15798 xref: EMBL:M27054 xref: EMBL:M27396 xref: HGNC:HGNC:753 xref: UniGene:Hs.489207 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032819 ! ASNS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006424 name: FOX1_human def: "Fox-1 homolog A gene" [UniProtKB:Q9NWB1] synonym: "A2BP" EXACT [UniProtKB:Q9NWB1] synonym: "A2BP1" EXACT [UniProtKB:Q9NWB1] synonym: "HRNBP1" EXACT [UniProtKB:Q9NWB1] xref: EMBL:AF094849 xref: EMBL:AF107203 xref: EMBL:AF109106 xref: EMBL:AF109107 xref: EMBL:AF109108 xref: EMBL:AF109109 xref: EMBL:AF109110 xref: EMBL:AF109111 xref: EMBL:AF109112 xref: EMBL:AF109113 xref: EMBL:AF109114 xref: EMBL:AF109115 xref: EMBL:AF109116 xref: EMBL:AF109117 xref: EMBL:AF109118 xref: EMBL:AF109119 xref: EMBL:AF109120 xref: EMBL:AF229057 xref: EMBL:AF448859 xref: EMBL:AK001027 xref: EMBL:BC113691 xref: UniGene:Hs.459842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061986 ! FOX1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006425 name: PSMC3IP_human def: "Homologous-pairing protein 2 homolog gene" [UniProtKB:Q9P2W1] synonym: "HOP2" EXACT [UniProtKB:Q9P2W1] synonym: "TBPIP" EXACT [UniProtKB:Q9P2W1] xref: EMBL:AB030304 xref: EMBL:AF440240 xref: EMBL:BC008792 xref: EMBL:L38933 xref: HGNC:HGNC:17928 xref: UniGene:Hs.702050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032571 ! HOP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006426 name: MYH10_human def: "Myosin-10 gene" [UniProtKB:P35580] xref: EMBL:BC117691 xref: EMBL:CH471108 xref: EMBL:M69181 xref: EMBL:S67247 xref: EMBL:U15618 xref: HGNC:HGNC:7568 xref: UniGene:Hs.16355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019194 ! MYH10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006427 name: PRTFDC1_human def: "Phosphoribosyltransferase domain-containing protein 1 gene" [UniProtKB:Q9NRG1] synonym: "HHGP" EXACT [UniProtKB:Q9NRG1] xref: EMBL:AB209792 xref: EMBL:AF226056 xref: EMBL:AK021950 xref: EMBL:AK222674 xref: EMBL:AL157385 xref: EMBL:AL512598 xref: EMBL:BC008662 xref: EMBL:CH471072 xref: HGNC:HGNC:23333 xref: UniGene:Hs.405619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032831 ! PRDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006428 name: NAE1_human def: "NEDD8-activating enzyme E1 regulatory subunit gene" [UniProtKB:Q13564] synonym: "APPBP1" EXACT [UniProtKB:Q13564] synonym: "HPP1" EXACT [UniProtKB:Q13564] xref: EMBL:AC004638 xref: EMBL:AL136798 xref: EMBL:AY197612 xref: EMBL:BC000480 xref: EMBL:BC013301 xref: EMBL:U50939 xref: HGNC:HGNC:621 xref: UniGene:Hs.460978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001758 ! ULA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0006429 name: ZNF318_human def: "Zinc finger protein 318 gene" [UniProtKB:Q5VUA4] synonym: "HRIHFB2436" EXACT [UniProtKB:Q5VUA4] xref: EMBL:AB015342 xref: EMBL:AF090114 xref: EMBL:AF121141 xref: EMBL:AL583834 xref: EMBL:AL590383 xref: EMBL:BC030687 xref: EMBL:BC098434 xref: HGNC:HGNC:13578 xref: UniGene:Hs.509718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032820 ! ZN318_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007184 name: PPP2R5B_human def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform gene" [UniProtKB:Q15173] xref: EMBL:BC045619 xref: EMBL:L42374 xref: EMBL:Z69028 xref: HGNC:HGNC:9310 xref: UniGene:Hs.75199 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025990 ! 2A5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007185 name: PPP2R5C_human def: "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform gene" [UniProtKB:Q13362] synonym: "KIAA0044" EXACT [UniProtKB:Q13362] xref: EMBL:BC016183 xref: EMBL:D26445 xref: EMBL:L42375 xref: EMBL:U37352 xref: EMBL:Z69030 xref: HGNC:HGNC:9311 xref: UniGene:Hs.368264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025995 ! Q96B13_HUMAN relationship: codes_for CCO:B0026004 ! 2A5G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007186 name: PPP2R2A_human def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform gene" [UniProtKB:P63151] xref: EMBL:BC041071 xref: EMBL:M64929 xref: HGNC:HGNC:9304 xref: UniGene:Hs.146339 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026114 ! 2ABA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007187 name: PPP2R2B_human def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform gene" [UniProtKB:Q00005] xref: EMBL:AC008728 xref: EMBL:BC031790 xref: EMBL:CH471062 xref: EMBL:M64930 xref: HGNC:HGNC:9305 xref: UniGene:Hs.655213 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026116 ! 2ABB_HUMAN relationship: codes_for CCO:B0026125 ! A6NEJ2_HUMAN relationship: codes_for CCO:B0029137 ! A8MU22_HUMAN relationship: codes_for CCO:B0029141 ! A8MW32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007188 name: PPP2R2D_human def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform gene" [UniProtKB:Q66LE6] synonym: "KIAA1541" EXACT [UniProtKB:Q66LE6] xref: EMBL:AB040974 xref: EMBL:AL732395 xref: EMBL:BC047379 xref: EMBL:CH471066 xref: HGNC:HGNC:23732 xref: UniGene:Hs.380372 xref: UniGene:Hs.657480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026111 ! 2ABD_HUMAN relationship: codes_for CCO:B0029136 ! A8MZB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007189 name: PPP2R2C_human def: "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform gene" [UniProtKB:Q9Y2T4] xref: EMBL:AC116317 xref: EMBL:AF086924 xref: EMBL:AF096153 xref: EMBL:AF096154 xref: EMBL:AF096155 xref: EMBL:AF096156 xref: EMBL:AF096157 xref: EMBL:AF096158 xref: EMBL:AF096159 xref: EMBL:AF096160 xref: EMBL:AK093115 xref: EMBL:BC032954 xref: EMBL:CH471131 xref: HGNC:HGNC:9306 xref: UniGene:Hs.479069 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026109 ! Q8NEC4_HUMAN relationship: codes_for CCO:B0026121 ! 2ABG_HUMAN relationship: codes_for CCO:B0029139 ! A8MSY7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007191 name: SERPINA1_human def: "Alpha-1-antitrypsin precursor gene" [UniProtKB:P01009] synonym: "AAT" EXACT [UniProtKB:P01009] synonym: "PI" EXACT [UniProtKB:P01009] synonym: "PRO0684" EXACT [UniProtKB:P01009] synonym: "PRO2209" EXACT [UniProtKB:P01009] xref: EMBL:AF113676 xref: EMBL:AF130068 xref: EMBL:AK315637 xref: EMBL:AM048838 xref: EMBL:BC011991 xref: EMBL:BC015642 xref: EMBL:BT019455 xref: EMBL:BX161449 xref: EMBL:BX247968 xref: EMBL:BX248002 xref: EMBL:BX248257 xref: EMBL:DQ682455 xref: EMBL:J00064 xref: EMBL:J00065 xref: EMBL:J00066 xref: EMBL:J00067 xref: EMBL:J02619 xref: EMBL:K01396 xref: EMBL:K02212 xref: EMBL:M11465 xref: EMBL:M26123 xref: EMBL:V00496 xref: EMBL:X01683 xref: EMBL:X02920 xref: HGNC:HGNC:8941 xref: UniGene:Hs.525557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028166 ! A1AT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007203 name: ABCA1_human def: "ATP-binding cassette sub-family A member 1 gene" [UniProtKB:O95477] synonym: "ABC1" EXACT [UniProtKB:O95477] synonym: "CERP" EXACT [UniProtKB:O95477] xref: EMBL:AB055982 xref: EMBL:AF165281 xref: EMBL:AF165282 xref: EMBL:AF165283 xref: EMBL:AF165284 xref: EMBL:AF165285 xref: EMBL:AF165286 xref: EMBL:AF165287 xref: EMBL:AF165288 xref: EMBL:AF165289 xref: EMBL:AF165290 xref: EMBL:AF165291 xref: EMBL:AF165292 xref: EMBL:AF165293 xref: EMBL:AF165294 xref: EMBL:AF165295 xref: EMBL:AF165296 xref: EMBL:AF165297 xref: EMBL:AF165298 xref: EMBL:AF165299 xref: EMBL:AF165300 xref: EMBL:AF165301 xref: EMBL:AF165302 xref: EMBL:AF165303 xref: EMBL:AF165304 xref: EMBL:AF165305 xref: EMBL:AF165306 xref: EMBL:AF165307 xref: EMBL:AF165308 xref: EMBL:AF165309 xref: EMBL:AF165310 xref: EMBL:AF275948 xref: EMBL:AF285167 xref: EMBL:AF287262 xref: EMBL:AJ012376 xref: EMBL:AL353685 xref: EMBL:AL359846 xref: HGNC:HGNC:29 xref: UniGene:Hs.429294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034197 ! ABCA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007204 name: ACTL6B_human def: "Actin-like protein 6B gene" [UniProtKB:O94805] synonym: "ACTL6" EXACT [UniProtKB:O94805] synonym: "BAF53B" EXACT [UniProtKB:O94805] xref: EMBL:AB015906 xref: EMBL:AC099394 xref: EMBL:AF041475 xref: EMBL:AF053356 xref: EMBL:BC020944 xref: HGNC:HGNC:160 xref: UniGene:Hs.259831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016782 ! ACL6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007205 name: ACTC1_human def: "Actin, alpha cardiac muscle 1 gene" [UniProtKB:P68032] synonym: "ACTC" EXACT [UniProtKB:P68032] xref: EMBL:BC009978 xref: EMBL:CR541795 xref: EMBL:J00070 xref: EMBL:J00071 xref: EMBL:J00072 xref: EMBL:J00073 xref: HGNC:HGNC:143 xref: UniGene:Hs.705440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015638 ! ACTC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007206 name: ACTG1_human def: "Actin, cytoplasmic 2 gene" [UniProtKB:P63261] synonym: "ACTB" EXACT [UniProtKB:P63261] synonym: "ACTG" EXACT [UniProtKB:P63261] xref: EMBL:BC000292 xref: EMBL:BC001920 xref: EMBL:BC007442 xref: EMBL:BC009848 xref: EMBL:BC010999 xref: EMBL:BC012050 xref: EMBL:BC015005 xref: EMBL:BC015695 xref: EMBL:BC015779 xref: EMBL:BC018774 xref: EMBL:BC053572 xref: EMBL:BT019856 xref: EMBL:M16247 xref: EMBL:M19283 xref: EMBL:X04098 xref: HGNC:HGNC:144 xref: UniGene:Hs.514581 xref: UniGene:Hs.520640 xref: UniGene:Hs.702191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015628 ! ACTG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007207 name: ACTG2_human def: "Actin, gamma-enteric smooth muscle gene" [UniProtKB:P63267] synonym: "ACTA3" EXACT [UniProtKB:P63267] synonym: "ACTL3" EXACT [UniProtKB:P63267] synonym: "ACTSG" EXACT [UniProtKB:P63267] xref: EMBL:AC073046 xref: EMBL:BC012617 xref: EMBL:BC094877 xref: EMBL:CR536515 xref: EMBL:CR541794 xref: EMBL:D00654 xref: EMBL:X16940 xref: HGNC:HGNC:145 xref: UniGene:Hs.516105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015644 ! ACTH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007209 name: ACTN3_human def: "Alpha-actinin-3 gene" [UniProtKB:Q08043] xref: EMBL:AP002748 xref: EMBL:BC099647 xref: EMBL:BC099649 xref: EMBL:M86407 xref: HGNC:HGNC:165 xref: UniGene:Hs.654432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020080 ! ACTN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007216 name: ADCY2_human def: "Adenylate cyclase type 2 gene" [UniProtKB:Q08462] synonym: "KIAA1060" EXACT [UniProtKB:Q08462] xref: EMBL:AB028983 xref: EMBL:AF410885 xref: EMBL:BC111743 xref: EMBL:L21993 xref: EMBL:X74210 xref: HGNC:HGNC:233 xref: UniGene:Hs.481545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020874 ! ADCY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007217 name: ADCY4_human def: "Adenylate cyclase type 4 gene" [UniProtKB:Q8NFM4] xref: EMBL:AF497516 xref: EMBL:AK056745 xref: EMBL:AK126468 xref: EMBL:BC117473 xref: EMBL:BC117475 xref: EMBL:CH471078 xref: HGNC:HGNC:235 xref: UniGene:Hs.443428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020873 ! Q6ZTM6_HUMAN relationship: codes_for CCO:B0020880 ! ADCY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007218 name: ADCY7_human def: "Adenylate cyclase type 7 gene" [UniProtKB:P51828] synonym: "KIAA0037" EXACT [UniProtKB:P51828] xref: EMBL:BC126271 xref: EMBL:D25538 xref: HGNC:HGNC:238 xref: UniGene:Hs.513578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020879 ! ADCY7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007219 name: ADAMDEC1_human def: "ADAM DEC1 precursor gene" [UniProtKB:O15204] xref: EMBL:BC069582 xref: EMBL:BC074877 xref: EMBL:BC074878 xref: EMBL:Y13323 xref: HGNC:HGNC:16299 xref: UniGene:Hs.521459 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024051 ! ADEC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007222 name: AFG3L2_human def: "AFG3-like protein 2 gene" [UniProtKB:Q9Y4W6] xref: EMBL:BC065016 xref: EMBL:Y18314 xref: HGNC:HGNC:315 xref: UniGene:Hs.528996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025289 ! AFG32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007223 name: AGR2_human def: "Anterior gradient protein 2 homolog precursor gene" [UniProtKB:O95994] synonym: "AG2" EXACT [UniProtKB:O95994] synonym: "UNQ515/PRO1030" EXACT [UniProtKB:O95994] xref: EMBL:AC073333 xref: EMBL:AF007791 xref: EMBL:AF038451 xref: EMBL:AF087879 xref: EMBL:AF088867 xref: EMBL:AF115926 xref: EMBL:AY359009 xref: EMBL:BC015503 xref: EMBL:BT007048 xref: HGNC:HGNC:328 xref: UniGene:Hs.530009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033164 ! AGR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007226 name: AIFM1_human def: "Apoptosis-inducing factor 1, mitochondrial precursor gene" [UniProtKB:O95831] synonym: "AIF" EXACT [UniProtKB:O95831] synonym: "PDCD8" EXACT [UniProtKB:O95831] xref: EMBL:AF100928 xref: EMBL:AF131759 xref: EMBL:AL049703 xref: EMBL:AL049704 xref: EMBL:AL139234 xref: EMBL:BC111065 xref: EMBL:CR457379 xref: HGNC:HGNC:8768 xref: UniGene:Hs.424932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014938 ! AIFM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007227 name: AKAP8L_human def: "A-kinase anchor protein 8-like gene" [UniProtKB:Q9ULX6] synonym: "HRIHFB2018" EXACT [UniProtKB:Q9ULX6] synonym: "NAKAP95" EXACT [UniProtKB:Q9ULX6] xref: EMBL:AB015332 xref: EMBL:AB025905 xref: EMBL:AF199414 xref: EMBL:AJ243467 xref: EMBL:BC000713 xref: HGNC:HGNC:29857 xref: UniGene:Hs.399800 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018469 ! AKP8L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007231 name: PAM_human def: "Peptidyl-glycine alpha-amidating monooxygenase precursor gene" [UniProtKB:P19021] xref: EMBL:AC008779 xref: EMBL:AF010472 xref: EMBL:BC018127 xref: EMBL:BT007419 xref: EMBL:M37721 xref: EMBL:S75037 xref: EMBL:S75038 xref: HGNC:HGNC:8596 xref: UniGene:Hs.369430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023169 ! A6NMR0_HUMAN relationship: codes_for CCO:B0023175 ! AMD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007235 name: METAP1_human def: "Methionine aminopeptidase 1 gene" [UniProtKB:P53582] synonym: "KIAA0094" EXACT [UniProtKB:P53582] xref: EMBL:BC030054 xref: EMBL:D42084 xref: HGNC:HGNC:15789 xref: UniGene:Hs.480364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029151 ! AMPM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007246 name: AGT_human def: "Angiotensinogen precursor gene" [UniProtKB:P01019] synonym: "SERPINA8" EXACT [UniProtKB:P01019] xref: EMBL:BC011519 xref: EMBL:K02215 xref: EMBL:M24686 xref: EMBL:M24687 xref: EMBL:M24688 xref: EMBL:M24689 xref: EMBL:M69110 xref: EMBL:S78529 xref: EMBL:S78530 xref: EMBL:X15324 xref: EMBL:X15325 xref: EMBL:X15326 xref: EMBL:X15327 xref: HGNC:HGNC:333 xref: UniGene:Hs.19383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032938 ! ANGT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007249 name: NPR1_human def: "Atrial natriuretic peptide receptor A precursor gene" [UniProtKB:P16066] synonym: "ANPRA" EXACT [UniProtKB:P16066] xref: EMBL:AB010491 xref: EMBL:AF190631 xref: EMBL:AL713889 xref: EMBL:BC063304 xref: EMBL:EU326310 xref: EMBL:S72628 xref: EMBL:X15357 xref: HGNC:HGNC:7943 xref: UniGene:Hs.490330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016680 ! ANPRA_HUMAN relationship: codes_for CCO:B0042773 ! B0ZBF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007250 name: NPR2_human def: "Atrial natriuretic peptide receptor B precursor gene" [UniProtKB:P20594] synonym: "ANPRB" EXACT [UniProtKB:P20594] xref: EMBL:AB005647 xref: EMBL:AJ005282 xref: EMBL:AL133410 xref: EMBL:BC023017 xref: EMBL:EU326311 xref: HGNC:HGNC:7944 xref: UniGene:Hs.78518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016679 ! A6NJF2_HUMAN relationship: codes_for CCO:B0016681 ! ANPRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007257 name: ANXA4_human def: "Annexin A4 gene" [UniProtKB:P09525] synonym: "ANX4" EXACT [UniProtKB:P09525] xref: EMBL:AC019206 xref: EMBL:AC092431 xref: EMBL:AC112787 xref: EMBL:BC000182 xref: EMBL:BC011659 xref: EMBL:D78152 xref: EMBL:M19383 xref: EMBL:M82809 xref: HGNC:HGNC:542 xref: UniGene:Hs.422986 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015859 ! ANXA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007258 name: ANXA5_human def: "Annexin A5 gene" [UniProtKB:P08758] synonym: "ANX5" EXACT [UniProtKB:P08758] synonym: "ENX2" EXACT [UniProtKB:P08758] synonym: "PP4" EXACT [UniProtKB:P08758] xref: EMBL:BC001429 xref: EMBL:BC004993 xref: EMBL:BC012804 xref: EMBL:BC012822 xref: EMBL:BC018671 xref: EMBL:CR536522 xref: EMBL:D00172 xref: EMBL:J03745 xref: EMBL:M18366 xref: EMBL:M19384 xref: EMBL:M21731 xref: EMBL:U01681 xref: EMBL:U01682 xref: EMBL:U01683 xref: EMBL:U01685 xref: EMBL:U01686 xref: EMBL:U01687 xref: EMBL:U01689 xref: EMBL:U01690 xref: EMBL:U01691 xref: EMBL:U05760 xref: EMBL:U05761 xref: EMBL:U05762 xref: EMBL:U05764 xref: EMBL:U05765 xref: EMBL:U05766 xref: EMBL:U05767 xref: EMBL:U05768 xref: EMBL:U05769 xref: EMBL:U05770 xref: EMBL:X12454 xref: HGNC:HGNC:543 xref: UniGene:Hs.480653 xref: UniGene:Hs.658778 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015822 ! ANXA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007261 name: ANXA9_human def: "Annexin A9 gene" [UniProtKB:O76027] synonym: "ANX31" EXACT [UniProtKB:O76027] xref: EMBL:AF230929 xref: EMBL:AJ009985 xref: EMBL:AL590133 xref: EMBL:BC005830 xref: EMBL:CR536481 xref: HGNC:HGNC:547 xref: UniGene:Hs.653223 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015830 ! ANXA9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007262 name: AQP1_human def: "Aquaporin-1 gene" [UniProtKB:P29972] synonym: "CHIP28" EXACT [UniProtKB:P29972] xref: EMBL:AC004691 xref: EMBL:AC005155 xref: EMBL:AF480415 xref: EMBL:AY953319 xref: EMBL:BC022486 xref: EMBL:M77829 xref: EMBL:S73482 xref: EMBL:U41517 xref: EMBL:U41518 xref: HGNC:HGNC:633 xref: UniGene:Hs.76152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034159 ! AQP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007263 name: ARHGEF15_human def: "Rho guanine nucleotide exchange factor 15 gene" [UniProtKB:O94989] synonym: "KIAA0915" EXACT [UniProtKB:O94989] xref: EMBL:AB020722 xref: EMBL:AK023853 xref: EMBL:BC036749 xref: HGNC:HGNC:15590 xref: UniGene:Hs.443109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029042 ! ARHGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007264 name: ARID4B_human def: "AT-rich interactive domain-containing protein 4B gene" [UniProtKB:Q4LE39] synonym: "BRCAA1" EXACT [UniProtKB:Q4LE39] synonym: "RBBP1L1" EXACT [UniProtKB:Q4LE39] synonym: "RBP1L1" EXACT [UniProtKB:Q4LE39] synonym: "SAP180" EXACT [UniProtKB:Q4LE39] xref: EMBL:AB030181 xref: EMBL:AB210032 xref: EMBL:AF083249 xref: EMBL:AF208045 xref: EMBL:AF214114 xref: EMBL:AF227899 xref: EMBL:AK023144 xref: EMBL:AL133418 xref: EMBL:AL133594 xref: EMBL:AL391994 xref: EMBL:AY220790 xref: EMBL:BC048959 xref: EMBL:BC062536 xref: EMBL:BC104632 xref: EMBL:BC130418 xref: EMBL:BX648820 xref: HGNC:HGNC:15550 xref: UniGene:Hs.533633 xref: UniGene:Hs.575782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026855 ! ARI4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007265 name: ARL1_human def: "ADP-ribosylation factor-like protein 1 gene" [UniProtKB:P40616] xref: EMBL:AF493887 xref: EMBL:BC007000 xref: EMBL:L28997 xref: HGNC:HGNC:692 xref: UniGene:Hs.372616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028281 ! ARL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007266 name: ACTR3_human def: "Actin-related protein 3 gene" [UniProtKB:P61158] synonym: "ARP3" EXACT [UniProtKB:P61158] xref: EMBL:AF006083 xref: EMBL:AF127773 xref: EMBL:BC044590 xref: HGNC:HGNC:170 xref: UniGene:Hs.433512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021502 ! ARP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007267 name: ACTR5_human def: "Actin-related protein 5 gene" [UniProtKB:Q9H9F9] synonym: "ARP5" EXACT [UniProtKB:Q9H9F9] xref: EMBL:AK022847 xref: EMBL:AL133519 xref: EMBL:AY211911 xref: EMBL:BC001324 xref: EMBL:BC006162 xref: EMBL:BC038402 xref: HGNC:HGNC:14671 xref: UniGene:Hs.371585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032592 ! ARP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007272 name: ATP2C1_human def: "Calcium-transporting ATPase type 2C member 1 gene" [UniProtKB:P98194] synonym: "HUSSY-28" EXACT [UniProtKB:P98194] synonym: "KIAA1347" EXACT [UniProtKB:P98194] synonym: "PMR1L" EXACT [UniProtKB:P98194] xref: EMBL:AB037768 xref: EMBL:AF181120 xref: EMBL:AF181121 xref: EMBL:AF189723 xref: EMBL:AF225981 xref: EMBL:AJ010953 xref: EMBL:AK001684 xref: EMBL:AK074692 xref: EMBL:AY268374 xref: EMBL:AY268375 xref: EMBL:BC028139 xref: HGNC:HGNC:13211 xref: UniGene:Hs.584884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026448 ! AT2C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007276 name: ATF2_human def: "Cyclic AMP-dependent transcription factor ATF-2 gene" [UniProtKB:P15336] synonym: "CREB2" EXACT [UniProtKB:P15336] synonym: "CREBP1" EXACT [UniProtKB:P15336] xref: EMBL:AC007435 xref: EMBL:AC074291 xref: EMBL:AC096649 xref: EMBL:AC131958 xref: EMBL:BC130335 xref: EMBL:BC130337 xref: EMBL:CH471058 xref: EMBL:M31630 xref: EMBL:U16028 xref: EMBL:X15875 xref: HGNC:HGNC:784 xref: UniGene:Hs.705370 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018367 ! ATF2_HUMAN relationship: codes_for CCO:B0018381 ! A1L3Z2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007286 name: ADAMTS1_human def: "A disintegrin and metalloproteinase with thrombospondin motifs 1 precursor gene" [UniProtKB:Q9UHI8] synonym: "KIAA1346" EXACT [UniProtKB:Q9UHI8] synonym: "METH1" EXACT [UniProtKB:Q9UHI8] xref: EMBL:AB037767 xref: EMBL:AF060152 xref: EMBL:AF170084 xref: EMBL:AF207664 xref: EMBL:AL162080 xref: EMBL:AP001697 xref: HGNC:HGNC:217 xref: UniGene:Hs.643357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019689 ! ATS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007294 name: ADAMTS8_human def: "A disintegrin and metalloproteinase with thrombospondin motifs 8 precursor gene" [UniProtKB:Q9UP79] synonym: "METH2" EXACT [UniProtKB:Q9UP79] xref: EMBL:AF060153 xref: EMBL:AF175283 xref: HGNC:HGNC:224 xref: UniGene:Hs.271605 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019651 ! ATS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007298 name: BCL2L13_human def: "Bcl-2-like 13 protein gene" [UniProtKB:Q9BXK5] synonym: "CD003" EXACT [UniProtKB:Q9BXK5] synonym: "MIL1" EXACT [UniProtKB:Q9BXK5] xref: EMBL:AF146568 xref: EMBL:AF183411 xref: EMBL:AF246665 xref: EMBL:AF325209 xref: EMBL:AL133029 xref: EMBL:BC007658 xref: EMBL:BC016037 xref: EMBL:CR456521 xref: HGNC:HGNC:17164 xref: UniGene:Hs.699302 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026744 ! B2L13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007300 name: ACOT7_human def: "Cytosolic acyl coenzyme A thioester hydrolase gene" [UniProtKB:O00154] synonym: "BACH" EXACT [UniProtKB:O00154] xref: EMBL:AB074415 xref: EMBL:AB074416 xref: EMBL:AB074417 xref: EMBL:AB074418 xref: EMBL:AB074419 xref: EMBL:AL031847 xref: EMBL:AL031848 xref: EMBL:BC017365 xref: EMBL:BT006888 xref: EMBL:D88894 xref: EMBL:U91316 xref: HGNC:HGNC:24157 xref: UniGene:Hs.126137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033823 ! BACH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007302 name: BDNF_human def: "Brain-derived neurotrophic factor precursor gene" [UniProtKB:P23560] xref: EMBL:AF400438 xref: EMBL:AY011481 xref: EMBL:BC029795 xref: EMBL:M37762 xref: EMBL:M61176 xref: EMBL:M61181 xref: EMBL:X60201 xref: EMBL:X91251 xref: HGNC:HGNC:1033 xref: UniGene:Hs.502182 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032721 ! BDNF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007304 name: BOK_human def: "Bcl-2-related ovarian killer protein gene" [UniProtKB:Q9UMX3] xref: EMBL:AF089746 xref: EMBL:AF174487 xref: EMBL:BC006203 xref: EMBL:BT007272 xref: HGNC:HGNC:1087 xref: UniGene:Hs.293753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029119 ! Q9UL32_HUMAN relationship: codes_for CCO:B0029122 ! BOK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007311 name: BRMS1L_human def: "Breast cancer metastasis-suppressor 1-like protein gene" [UniProtKB:Q5PSV4] xref: EMBL:AL162311 xref: EMBL:AY827074 xref: EMBL:BC006250 xref: HGNC:HGNC:20512 xref: UniGene:Hs.525299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023930 ! BRM1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007319 name: BTAF1_human def: "TATA-binding protein-associated factor 172 gene" [UniProtKB:O14981] synonym: "TAF172" EXACT [UniProtKB:O14981] xref: EMBL:AF038362 xref: EMBL:AF166118 xref: EMBL:AJ001017 xref: HGNC:HGNC:17307 xref: UniGene:Hs.500526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016937 ! BTAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007322 name: BUD31_human def: "Protein BUD31 homolog gene" [UniProtKB:P41223] synonym: "EDG2" EXACT [UniProtKB:P41223] xref: EMBL:AC004922 xref: EMBL:BC022821 xref: EMBL:BC104670 xref: EMBL:CR456951 xref: EMBL:S77329 xref: EMBL:U11861 xref: HGNC:HGNC:29629 xref: UniGene:Hs.380233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019606 ! BUD31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007340 name: CTSK_human def: "Cathepsin K precursor gene" [UniProtKB:P43235] synonym: "CTSO" EXACT [UniProtKB:P43235] synonym: "CTSO2" EXACT [UniProtKB:P43235] xref: EMBL:BC016058 xref: EMBL:S79895 xref: EMBL:U13665 xref: EMBL:U20280 xref: EMBL:X82153 xref: HGNC:HGNC:2536 xref: UniGene:Hs.632466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031707 ! CATK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007357 name: CCDC7_human def: "Coiled-coil domain-containing protein 7 gene" [UniProtKB:Q96M83] xref: EMBL:AK057324 xref: EMBL:BC022020 xref: EMBL:BC042672 xref: HGNC:HGNC:26533 xref: UniGene:Hs.585464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019119 ! CCDC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007358 name: CCNL2_human def: "Cyclin-L2 gene" [UniProtKB:Q96S94] synonym: "SB138" EXACT [UniProtKB:Q96S94] xref: EMBL:AF087903 xref: EMBL:AK074112 xref: EMBL:AL391244 xref: EMBL:AL834432 xref: EMBL:AL834441 xref: EMBL:AY037150 xref: EMBL:AY116620 xref: EMBL:BC016333 xref: EMBL:BC071622 xref: EMBL:CR628411 xref: HGNC:HGNC:20570 xref: UniGene:Hs.515704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023940 ! CCNL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007359 name: CCR10_human def: "C-C chemokine receptor type 10 gene" [UniProtKB:P46092] synonym: "GPR2" EXACT [UniProtKB:P46092] xref: EMBL:AF208237 xref: EMBL:AF215981 xref: EMBL:AY429103 xref: EMBL:BC098132 xref: EMBL:BC098157 xref: EMBL:BC098304 xref: EMBL:BC099840 xref: EMBL:U13667 xref: HGNC:HGNC:4474 xref: UniGene:Hs.703555 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018440 ! CCR10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007360 name: CCRL1_human def: "C-C chemokine receptor type 11 gene" [UniProtKB:Q9NPB9] synonym: "CCBP2" EXACT [UniProtKB:Q9NPB9] synonym: "CCR11" EXACT [UniProtKB:Q9NPB9] synonym: "VSHK1" EXACT [UniProtKB:Q9NPB9] xref: EMBL:AF110640 xref: EMBL:AF193507 xref: EMBL:AF233281 xref: EMBL:AY221094 xref: EMBL:BC069438 xref: HGNC:HGNC:1611 xref: UniGene:Hs.310512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018438 ! CCRL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007363 name: CDA_human def: "Cytidine deaminase gene" [UniProtKB:P32320] synonym: "CDD" EXACT [UniProtKB:P32320] xref: EMBL:AF061655 xref: EMBL:AF061656 xref: EMBL:AF061657 xref: EMBL:AF061658 xref: EMBL:AJ000474 xref: EMBL:AL391357 xref: EMBL:BC054036 xref: EMBL:L27943 xref: EMBL:S52873 xref: HGNC:HGNC:1712 xref: UniGene:Hs.466910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031622 ! CDD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007364 name: CDIPT_human def: "CDP-diacylglycerol--inositol 3-phosphatidyltransferase gene" [UniProtKB:O14735] synonym: "PIS" EXACT [UniProtKB:O14735] synonym: "PIS1" EXACT [UniProtKB:O14735] xref: EMBL:AF014807 xref: EMBL:AK131349 xref: EMBL:BC001444 xref: EMBL:BT007301 xref: EMBL:CR542016 xref: HGNC:HGNC:1769 xref: UniGene:Hs.121549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027593 ! CDIPT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007370 name: CDYL_human def: "Chromodomain Y-like protein gene" [UniProtKB:Q9Y232] synonym: "CDYL1" EXACT [UniProtKB:Q9Y232] xref: EMBL:AF081258 xref: EMBL:AF081259 xref: EMBL:AL022725 xref: EMBL:AL050164 xref: EMBL:AL356747 xref: EMBL:AL359643 xref: EMBL:BC061516 xref: EMBL:BC108725 xref: EMBL:BC119682 xref: HGNC:HGNC:1811 xref: UniGene:Hs.269092 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028736 ! CDYL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007372 name: CEACAM1_human def: "Carcinoembryonic antigen-related cell adhesion molecule 1 precursor gene" [UniProtKB:P13688] synonym: "BGP" EXACT [UniProtKB:P13688] synonym: "BGP1" EXACT [UniProtKB:P13688] xref: EMBL:AC004785 xref: EMBL:D90311 xref: EMBL:D90312 xref: EMBL:D90313 xref: EMBL:J03858 xref: EMBL:M69176 xref: EMBL:M72238 xref: EMBL:M76742 xref: EMBL:X14831 xref: EMBL:X16354 xref: EMBL:X67277 xref: HGNC:HGNC:1814 xref: UniGene:Hs.512682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029727 ! CEAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007375 name: CEACAM5_human def: "Carcinoembryonic antigen-related cell adhesion molecule 5 gene" [UniProtKB:Q8N4D0] xref: EMBL:BC034671 xref: HGNC:HGNC:1817 xref: UniGene:Hs.466814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029706 ! Q8N4D0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007376 name: CEACAM6_human def: "Carcinoembryonic antigen-related cell adhesion molecule 6 precursor gene" [UniProtKB:P40199] synonym: "NCA" EXACT [UniProtKB:P40199] xref: EMBL:BC005008 xref: EMBL:M18728 xref: EMBL:M29541 xref: HGNC:HGNC:1818 xref: UniGene:Hs.466814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029695 ! CEAM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007379 name: CELSR2_human def: "Cadherin EGF LAG seven-pass G-type receptor 2 precursor gene" [UniProtKB:Q9HCU4] synonym: "CDHF10" EXACT [UniProtKB:Q9HCU4] synonym: "EGFL2" EXACT [UniProtKB:Q9HCU4] synonym: "KIAA0279" EXACT [UniProtKB:Q9HCU4] synonym: "MEGF3" EXACT [UniProtKB:Q9HCU4] xref: EMBL:AB065955 xref: EMBL:AF234887 xref: EMBL:AL390252 xref: EMBL:D87469 xref: HGNC:HGNC:3231 xref: UniGene:Hs.57652 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032349 ! CELR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007380 name: CENTB1_human def: "Centaurin-beta-1 gene" [UniProtKB:Q15027] synonym: "KIAA0050" EXACT [UniProtKB:Q15027] xref: EMBL:BC018543 xref: EMBL:BT009788 xref: EMBL:D30758 xref: HGNC:HGNC:16467 xref: UniGene:Hs.337242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033903 ! CENB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007381 name: CENTB2_human def: "Centaurin-beta-2 gene" [UniProtKB:Q15057] synonym: "KIAA0041" EXACT [UniProtKB:Q15057] xref: EMBL:AJ238248 xref: EMBL:BC031005 xref: EMBL:BC060767 xref: EMBL:D26069 xref: HGNC:HGNC:16469 xref: UniGene:Hs.654597 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033904 ! CENB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007382 name: CENTD1_human def: "Centaurin-delta-1 gene" [UniProtKB:Q8WZ64] synonym: "ARAP2" EXACT [UniProtKB:Q8WZ64] synonym: "KIAA0580" EXACT [UniProtKB:Q8WZ64] xref: EMBL:AB011152 xref: EMBL:AC098827 xref: EMBL:AC104078 xref: EMBL:AC108033 xref: EMBL:AC109818 xref: EMBL:AC116623 xref: EMBL:AF411982 xref: EMBL:AF439781 xref: EMBL:AY049733 xref: EMBL:BC105089 xref: EMBL:BC105091 xref: HGNC:HGNC:16924 xref: UniGene:Hs.479451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024595 ! Q2M2Z8_HUMAN relationship: codes_for CCO:B0024600 ! CEND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007386 name: CHD1_human def: "Chromodomain-helicase-DNA-binding protein 1 gene" [UniProtKB:O14646] xref: EMBL:AF006513 xref: HGNC:HGNC:1915 xref: UniGene:Hs.643465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021030 ! CHD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007387 name: CHD2_human def: "Chromodomain-helicase-DNA-binding protein 2 gene" [UniProtKB:O14647] xref: EMBL:AC013394 xref: EMBL:AF006514 xref: EMBL:CR978407 xref: HGNC:HGNC:1917 xref: UniGene:Hs.220864 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021032 ! CHD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007389 name: CHIC2_human def: "Cysteine-rich hydrophobic domain 2 protein gene" [UniProtKB:Q9UKJ5] synonym: "BTL" EXACT [UniProtKB:Q9UKJ5] xref: EMBL:AF159423 xref: EMBL:BC034691 xref: HGNC:HGNC:1935 xref: UniGene:Hs.335393 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020052 ! CHIC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007390 name: CHL1_human def: "Neural cell adhesion molecule L1-like protein precursor gene" [UniProtKB:O00533] synonym: "CALL" EXACT [UniProtKB:O00533] xref: EMBL:AB209329 xref: EMBL:AF002246 xref: EMBL:BC104918 xref: HGNC:HGNC:1939 xref: UniGene:Hs.148909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015673 ! CHL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007392 name: CIRBP_human def: "Cold-inducible RNA-binding protein gene" [UniProtKB:Q14011] synonym: "A18HNRNP" EXACT [UniProtKB:Q14011] synonym: "CIRP" EXACT [UniProtKB:Q14011] xref: EMBL:AC004258 xref: EMBL:AF021336 xref: EMBL:BC000403 xref: EMBL:BC000901 xref: EMBL:D78134 xref: HGNC:HGNC:1982 xref: UniGene:Hs.634522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032462 ! CIRBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007393 name: CITED1_human def: "Cbp/p300-interacting transactivator 1 gene" [UniProtKB:Q99966] synonym: "MSG1" EXACT [UniProtKB:Q99966] xref: EMBL:BC004240 xref: EMBL:U65092 xref: HGNC:HGNC:1986 xref: UniGene:Hs.40403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021706 ! CITE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007394 name: CITED4_human def: "Cbp/p300-interacting transactivator 4 gene" [UniProtKB:Q96RK1] synonym: "MRG2" EXACT [UniProtKB:Q96RK1] xref: EMBL:AF362074 xref: EMBL:AF466291 xref: EMBL:BC035496 xref: EMBL:BC052559 xref: HGNC:HGNC:18696 xref: UniGene:Hs.355820 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021707 ! CITE4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007398 name: CLOCK_human def: "Circadian locomoter output cycles protein kaput gene" [UniProtKB:O15516] synonym: "KIAA0334" EXACT [UniProtKB:O15516] xref: EMBL:AB002332 xref: EMBL:AB005535 xref: EMBL:AF011568 xref: EMBL:AF097442 xref: EMBL:AF097443 xref: EMBL:AF097444 xref: EMBL:AF097445 xref: EMBL:AF097446 xref: EMBL:AF097447 xref: EMBL:AF097448 xref: EMBL:AF097449 xref: EMBL:AF097450 xref: EMBL:AF097451 xref: EMBL:AF097452 xref: EMBL:AF097453 xref: EMBL:AF097454 xref: EMBL:AF097455 xref: EMBL:AF097456 xref: EMBL:AF097457 xref: EMBL:AF097458 xref: EMBL:BC126157 xref: EMBL:BC126159 xref: HGNC:HGNC:2082 xref: UniGene:Hs.436975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026531 ! CLOCK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007403 name: CNOT1_human def: "CCR4-NOT transcription complex subunit 1 gene" [UniProtKB:A5YKK6] synonym: "AD-005" EXACT [UniProtKB:A5YKK6] synonym: "CDC39" EXACT [UniProtKB:A5YKK6] synonym: "KIAA1007" EXACT [UniProtKB:A5YKK6] synonym: "NOT1" EXACT [UniProtKB:A5YKK6] xref: EMBL:AB023224 xref: EMBL:AC009118 xref: EMBL:AC010287 xref: EMBL:AF110778 xref: EMBL:AL117492 xref: EMBL:BC000779 xref: EMBL:BC024317 xref: EMBL:BC040523 xref: EMBL:BX537840 xref: EMBL:CR749237 xref: EMBL:EF553522 xref: HGNC:HGNC:7877 xref: UniGene:Hs.460923 xref: UniGene:Hs.655689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032072 ! CNOT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007404 name: CNOT6_human def: "CCR4-NOT transcription complex subunit 6 gene" [UniProtKB:Q9ULM6] synonym: "CCR4" EXACT [UniProtKB:Q9ULM6] synonym: "KIAA1194" EXACT [UniProtKB:Q9ULM6] xref: EMBL:AB033020 xref: HGNC:HGNC:14099 xref: UniGene:Hs.654984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019074 ! CNOT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007405 name: CNTFR_human def: "Ciliary neurotrophic factor receptor alpha precursor gene" [UniProtKB:P26992] xref: EMBL:BC001492 xref: EMBL:L38022 xref: EMBL:L38023 xref: EMBL:L38024 xref: EMBL:L38025 xref: EMBL:M73238 xref: HGNC:HGNC:2170 xref: UniGene:Hs.129966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026846 ! CNTFR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007408 name: CFL1_human def: "Cofilin-1 gene" [UniProtKB:P23528] synonym: "CFL" EXACT [UniProtKB:P23528] xref: EMBL:BC011005 xref: EMBL:BC012265 xref: EMBL:BC012318 xref: EMBL:BC018256 xref: EMBL:BT006846 xref: EMBL:D00682 xref: EMBL:U21909 xref: EMBL:X95404 xref: HGNC:HGNC:1874 xref: UniGene:Hs.170622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033320 ! COF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007409 name: CFL2_human def: "Cofilin-2 gene" [UniProtKB:Q9Y281] xref: EMBL:AF134802 xref: EMBL:AF134803 xref: EMBL:AF242299 xref: EMBL:AF283513 xref: EMBL:BC011444 xref: EMBL:BC022364 xref: EMBL:BC022876 xref: HGNC:HGNC:1875 xref: UniGene:Hs.180141 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033309 ! COF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007414 name: CORO1B_human def: "Coronin-1B gene" [UniProtKB:Q9BR76] xref: EMBL:BC006449 xref: HGNC:HGNC:2253 xref: UniGene:Hs.6191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025107 ! COR1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007415 name: CORO1C_human def: "Coronin-1C gene" [UniProtKB:Q9ULV4] synonym: "CRNN4" EXACT [UniProtKB:Q9ULV4] xref: EMBL:AB030656 xref: EMBL:AL162070 xref: EMBL:BC002342 xref: HGNC:HGNC:2254 xref: UniGene:Hs.701585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025115 ! COR1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007416 name: CORO2A_human def: "Coronin-2A gene" [UniProtKB:Q92828] synonym: "IR10" EXACT [UniProtKB:Q92828] synonym: "WDR2" EXACT [UniProtKB:Q92828] xref: EMBL:BC000010 xref: EMBL:BC011690 xref: EMBL:U57057 xref: EMBL:U57058 xref: HGNC:HGNC:2255 xref: UniGene:Hs.113094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025112 ! COR2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007419 name: NR2F1_human def: "COUP transcription factor 1 gene" [UniProtKB:P10589] synonym: "EAR3" EXACT [UniProtKB:P10589] synonym: "ERBAL3" EXACT [UniProtKB:P10589] synonym: "TFCOUP1" EXACT [UniProtKB:P10589] xref: EMBL:BC004154 xref: EMBL:BC017493 xref: EMBL:X12795 xref: EMBL:X16155 xref: HGNC:HGNC:7975 xref: UniGene:Hs.519445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024874 ! COT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007420 name: NR2F2_human def: "COUP transcription factor 2 gene" [UniProtKB:P24468] synonym: "ARP1" EXACT [UniProtKB:P24468] synonym: "TFCOUP2" EXACT [UniProtKB:P24468] xref: EMBL:AK301595 xref: EMBL:BC014664 xref: EMBL:BC042897 xref: EMBL:BC106083 xref: EMBL:CH471101 xref: EMBL:M62760 xref: EMBL:M64497 xref: EMBL:U60477 xref: HGNC:HGNC:7976 xref: UniGene:Hs.701977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024875 ! COT2_HUMAN relationship: codes_for CCO:B0024889 ! Q3KQR7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007427 name: CRTAM_human def: "Cytotoxic and regulatory T-cell molecule precursor gene" [UniProtKB:O95727] xref: EMBL:AB209830 xref: EMBL:AF001622 xref: EMBL:BC070266 xref: HGNC:HGNC:24313 xref: UniGene:Hs.159523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015065 ! CRTAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007438 name: CTGLF1_human def: "Centaurin-gamma-like family member 1 gene" [UniProtKB:Q96P64] synonym: "MRIP2" EXACT [UniProtKB:Q96P64] xref: EMBL:AF411132 xref: EMBL:BC048341 xref: HGNC:HGNC:23459 xref: UniGene:Hs.536192 xref: UniGene:Hs.656384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033972 ! CTLF1_HUMAN relationship: codes_for CCO:B0033974 ! Q86XV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007439 name: CTGLF3_human def: "Centaurin-gamma-like family member 3 gene" [UniProtKB:Q5VW22] xref: EMBL:AL442003 xref: HGNC:HGNC:23466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033973 ! CTLF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007440 name: CTGLF4_human def: "Centaurin-gamma-like family member 4 gene" [UniProtKB:Q5VUJ5] xref: EMBL:AL589822 xref: HGNC:HGNC:23465 xref: UniGene:Hs.528346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033969 ! CTLF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007441 name: CTGLF5_human def: "Centaurin-gamma-like family member 5 gene" [UniProtKB:Q5SRD3] xref: EMBL:AL672187 xref: HGNC:HGNC:23464 xref: UniGene:Hs.536192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033967 ! CTLF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007442 name: CTGLF6_human def: "Centaurin-gamma-like family member 6 gene" [UniProtKB:Q5VTM2] xref: EMBL:AL591684 xref: HGNC:HGNC:23463 xref: UniGene:Hs.645346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033965 ! CTLF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007444 name: DBF4B_human def: "Protein DBF4 homolog B gene" [UniProtKB:Q8NFT6] synonym: "ASKL1" EXACT [UniProtKB:Q8NFT6] synonym: "DRF1" EXACT [UniProtKB:Q8NFT6] xref: EMBL:AF448801 xref: EMBL:AF465820 xref: EMBL:AK023149 xref: EMBL:BC016158 xref: EMBL:CH471178 xref: HGNC:HGNC:17883 xref: UniGene:Hs.369998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033478 ! DBF4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007446 name: DCDC2B_human def: "Doublecortin domain-containing protein 2B gene" [UniProtKB:A2VCK2] xref: EMBL:BC128073 xref: HGNC:HGNC:32576 xref: UniGene:Hs.424588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018807 ! DCD2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007447 name: DCDC2_human def: "Doublecortin domain-containing protein 2 gene" [UniProtKB:Q9UHG0] synonym: "KIAA1154" EXACT [UniProtKB:Q9UHG0] synonym: "RU2" EXACT [UniProtKB:Q9UHG0] xref: EMBL:AB032980 xref: EMBL:AF181720 xref: EMBL:AF181721 xref: EMBL:AL133043 xref: EMBL:AL359389 xref: EMBL:AL359713 xref: EMBL:AL591344 xref: EMBL:BC050704 xref: HGNC:HGNC:18141 xref: UniGene:Hs.659324 xref: UniGene:Hs.660365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018804 ! Q5T3Y5_HUMAN relationship: codes_for CCO:B0018806 ! DCDC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007451 name: DDX56_human def: "Probable ATP-dependent RNA helicase DDX56 gene" [UniProtKB:Q9NY93] synonym: "DDX21" EXACT [UniProtKB:Q9NY93] synonym: "NOH61" EXACT [UniProtKB:Q9NY93] xref: EMBL:AF247666 xref: EMBL:AJ131712 xref: EMBL:AK022774 xref: EMBL:AL136700 xref: EMBL:BC001235 xref: EMBL:CR457213 xref: HGNC:HGNC:18193 xref: UniGene:Hs.654762 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030377 ! DDX56_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007455 name: DSTN_human def: "Destrin gene" [UniProtKB:P60981] synonym: "ACTDP" EXACT [UniProtKB:P60981] synonym: "DSN" EXACT [UniProtKB:P60981] xref: EMBL:AL132765 xref: EMBL:BC009477 xref: EMBL:CR457042 xref: EMBL:S65738 xref: HGNC:HGNC:15750 xref: UniGene:Hs.304192 xref: UniGene:Hs.705996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033316 ! DEST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007456 name: DFFB_human def: "DNA fragmentation factor subunit beta gene" [UniProtKB:O76075] synonym: "CAD" EXACT [UniProtKB:O76075] synonym: "DFF2" EXACT [UniProtKB:O76075] synonym: "DFF40" EXACT [UniProtKB:O76075] xref: EMBL:AB013918 xref: EMBL:AB028911 xref: EMBL:AB028912 xref: EMBL:AB028913 xref: EMBL:AF039210 xref: EMBL:AF064019 xref: EMBL:BC048797 xref: HGNC:HGNC:2773 xref: UniGene:Hs.133089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015270 ! DFFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007460 name: DIRAS1_human def: "GTP-binding protein Di-Ras1 gene" [UniProtKB:O95057] synonym: "GBTS1" EXACT [UniProtKB:O95057] synonym: "RIG" EXACT [UniProtKB:O95057] xref: EMBL:AB076888 xref: EMBL:AC006538 xref: EMBL:AY056037 xref: EMBL:AY059641 xref: EMBL:AY180973 xref: EMBL:BC030660 xref: HGNC:HGNC:19127 xref: UniGene:Hs.172753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025350 ! DIRA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007461 name: DLG3_human def: "Disks large homolog 3 gene" [UniProtKB:Q92796] synonym: "KIAA1232" EXACT [UniProtKB:Q92796] xref: EMBL:AB033058 xref: EMBL:U49089 xref: HGNC:HGNC:2902 xref: UniGene:Hs.522680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023306 ! DLG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007462 name: DLG4_human def: "Disks large homolog 4 gene" [UniProtKB:P78352] synonym: "PSD95" EXACT [UniProtKB:P78352] xref: EMBL:AF156495 xref: EMBL:U68138 xref: EMBL:U83192 xref: HGNC:HGNC:2903 xref: UniGene:Hs.463928 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023311 ! DLG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007463 name: DNA2_human def: "DNA2-like helicase gene" [UniProtKB:P51530] synonym: "DNA2L" EXACT [UniProtKB:P51530] synonym: "KIAA0083" EXACT [UniProtKB:P51530] xref: EMBL:AL136233 xref: EMBL:BC041115 xref: EMBL:BC053574 xref: EMBL:BC063664 xref: EMBL:BC111740 xref: EMBL:D42046 xref: HGNC:HGNC:2939 xref: UniGene:Hs.532446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030933 ! DNA2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007464 name: DNAJB1_human def: "DnaJ homolog subfamily B member 1 gene" [UniProtKB:P25685] synonym: "DNAJ1" EXACT [UniProtKB:P25685] synonym: "HDJ1" EXACT [UniProtKB:P25685] synonym: "HSPF1" EXACT [UniProtKB:P25685] xref: EMBL:BC002352 xref: EMBL:BC019827 xref: EMBL:D49547 xref: EMBL:D85429 xref: EMBL:X62421 xref: HGNC:HGNC:5270 xref: UniGene:Hs.515210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016220 ! DNJB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007465 name: DNAJB4_human def: "DnaJ homolog subfamily B member 4 gene" [UniProtKB:Q9UDY4] synonym: "DNAJW" EXACT [UniProtKB:Q9UDY4] synonym: "HLJ1" EXACT [UniProtKB:Q9UDY4] xref: EMBL:BC034721 xref: EMBL:U40992 xref: EMBL:U41290 xref: HGNC:HGNC:14886 xref: UniGene:Hs.13852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016224 ! DNJB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007467 name: DNMT1_human def: "DNA (cytosine-5)-methyltransferase 1 gene" [UniProtKB:P26358] synonym: "AIM" EXACT [UniProtKB:P26358] synonym: "CXXC9" EXACT [UniProtKB:P26358] synonym: "DNMT" EXACT [UniProtKB:P26358] xref: EMBL:AC010077 xref: EMBL:AC011511 xref: EMBL:AC020931 xref: EMBL:AF169120 xref: EMBL:AF180682 xref: EMBL:X63692 xref: HGNC:HGNC:2976 xref: UniGene:Hs.202672 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032607 ! DNMT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007471 name: DPH3_human def: "DPH3 homolog gene" [UniProtKB:Q96FX2] synonym: "DESR1" EXACT [UniProtKB:Q96FX2] synonym: "ZCSL2" EXACT [UniProtKB:Q96FX2] xref: EMBL:AK022970 xref: EMBL:BC010181 xref: HGNC:HGNC:27717 xref: UniGene:Hs.388087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026978 ! DPH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007474 name: DUSP2_human def: "Dual specificity protein phosphatase 2 gene" [UniProtKB:Q05923] synonym: "PAC1" EXACT [UniProtKB:Q05923] xref: EMBL:BC007771 xref: EMBL:L11329 xref: EMBL:U23853 xref: HGNC:HGNC:3068 xref: UniGene:Hs.1183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021669 ! DUS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007475 name: DNM1_human def: "Dynamin-1 gene" [UniProtKB:Q05193] synonym: "DNM" EXACT [UniProtKB:Q05193] xref: EMBL:AL590708 xref: EMBL:BC050279 xref: EMBL:BC063850 xref: EMBL:L07807 xref: EMBL:L07808 xref: EMBL:L07809 xref: EMBL:L07810 xref: HGNC:HGNC:2972 xref: UniGene:Hs.522413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022139 ! DYN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007478 name: EDNRA_human def: "Endothelin-1 receptor precursor gene" [UniProtKB:P25101] synonym: "ETA" EXACT [UniProtKB:P25101] synonym: "ETRA" EXACT [UniProtKB:P25101] xref: EMBL:AF014826 xref: EMBL:AY275462 xref: EMBL:AY422989 xref: EMBL:BC022511 xref: EMBL:D11151 xref: EMBL:D90348 xref: EMBL:L06622 xref: EMBL:S45956 xref: EMBL:S55772 xref: EMBL:S57498 xref: EMBL:S63938 xref: EMBL:S67127 xref: EMBL:S81539 xref: EMBL:S81542 xref: EMBL:S81545 xref: EMBL:X61950 xref: HGNC:HGNC:3179 xref: UniGene:Hs.183713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018695 ! EDNRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007479 name: EDNRB_human def: "Endothelin B receptor precursor gene" [UniProtKB:P24530] synonym: "ETRB" EXACT [UniProtKB:P24530] xref: EMBL:AF114165 xref: EMBL:AJ458188 xref: EMBL:AJ458189 xref: EMBL:AJ458190 xref: EMBL:AJ458191 xref: EMBL:AK290699 xref: EMBL:AL139002 xref: EMBL:AY275463 xref: EMBL:AY547312 xref: EMBL:BC014472 xref: EMBL:CH471093 xref: EMBL:D13168 xref: EMBL:D90402 xref: EMBL:L06623 xref: EMBL:M74921 xref: EMBL:S44866 xref: EMBL:S57283 xref: EMBL:X99250 xref: HGNC:HGNC:3180 xref: UniGene:Hs.82002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018697 ! EDNRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007480 name: EFS_human def: "Embryonal Fyn-associated substrate gene" [UniProtKB:O43281] synonym: "CASS3" EXACT [UniProtKB:O43281] xref: EMBL:AB001466 xref: EMBL:AB001467 xref: EMBL:BC034246 xref: HGNC:HGNC:16898 xref: UniGene:Hs.24587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028938 ! EFS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007481 name: EGLN1_human def: "Egl nine homolog 1 gene" [UniProtKB:Q9GZT9] synonym: "C1orf12" EXACT [UniProtKB:Q9GZT9] synonym: "PNAS-118" EXACT [UniProtKB:Q9GZT9] synonym: "PNAS-137" EXACT [UniProtKB:Q9GZT9] xref: EMBL:AF229245 xref: EMBL:AF246630 xref: EMBL:AF246631 xref: EMBL:AF277174 xref: EMBL:AF277176 xref: EMBL:AJ310543 xref: EMBL:AL117352 xref: EMBL:AL445524 xref: EMBL:AL833885 xref: HGNC:HGNC:1232 xref: UniGene:Hs.444450 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029351 ! EGLN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007482 name: EGLN2_human def: "Egl nine homolog 2 gene" [UniProtKB:Q96KS0] synonym: "EIT6" EXACT [UniProtKB:Q96KS0] xref: EMBL:AJ310544 xref: EMBL:AY040565 xref: EMBL:BC001723 xref: EMBL:BC036051 xref: HGNC:HGNC:14660 xref: UniGene:Hs.515417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029357 ! EGLN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007483 name: EGLN3_human def: "Egl nine homolog 3 gene" [UniProtKB:Q9H6Z9] xref: EMBL:AJ310545 xref: EMBL:AK025273 xref: EMBL:BC010992 xref: EMBL:BC064924 xref: EMBL:BC105939 xref: EMBL:BC111057 xref: HGNC:HGNC:14661 xref: UniGene:Hs.135507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029358 ! EGLN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007486 name: EID3_human def: "EP300-interacting inhibitor of differentiation 3 gene" [UniProtKB:Q8N140] xref: EMBL:AK098698 xref: EMBL:BC027612 xref: EMBL:CH471054 xref: HGNC:HGNC:32961 xref: UniGene:Hs.659857 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032335 ! EID3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007487 name: C11orf79_human def: "Protein EMI5 homolog, mitochondrial precursor gene" [UniProtKB:Q9NX18] xref: EMBL:AK000494 xref: EMBL:BC002331 xref: HGNC:HGNC:26034 xref: UniGene:Hs.313247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025227 ! EMI5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007491 name: EPHA1_human def: "Ephrin type-A receptor 1 precursor gene" [UniProtKB:P21709] synonym: "EPH" EXACT [UniProtKB:P21709] synonym: "EPHT" EXACT [UniProtKB:P21709] synonym: "EPHT1" EXACT [UniProtKB:P21709] xref: EMBL:AC092214 xref: EMBL:AF101165 xref: EMBL:AF101166 xref: EMBL:AF101167 xref: EMBL:AF101168 xref: EMBL:AF101169 xref: EMBL:AF101170 xref: EMBL:AF101171 xref: EMBL:M18391 xref: EMBL:Z27409 xref: HGNC:HGNC:3385 xref: UniGene:Hs.89839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014973 ! EPHA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007492 name: EPHA3_human def: "Ephrin type-A receptor 3 precursor gene" [UniProtKB:P29320] synonym: "ETK" EXACT [UniProtKB:P29320] synonym: "ETK1" EXACT [UniProtKB:P29320] synonym: "HEK" EXACT [UniProtKB:P29320] synonym: "TYRO4" EXACT [UniProtKB:P29320] xref: EMBL:AF213459 xref: EMBL:AF213460 xref: EMBL:BC063282 xref: EMBL:M83941 xref: HGNC:HGNC:3387 xref: UniGene:Hs.123642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014952 ! Q6P4R6_HUMAN relationship: codes_for CCO:B0014967 ! EPHA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007493 name: EPHA4_human def: "Ephrin type-A receptor 4 precursor gene" [UniProtKB:P54764] synonym: "HEK8" EXACT [UniProtKB:P54764] synonym: "SEK" EXACT [UniProtKB:P54764] synonym: "TYRO1" EXACT [UniProtKB:P54764] xref: EMBL:BC105000 xref: EMBL:BC105002 xref: EMBL:L36645 xref: HGNC:HGNC:3388 xref: UniGene:Hs.371218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014942 ! EPHA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007494 name: EPHA5_human def: "Ephrin type-A receptor 5 precursor gene" [UniProtKB:P54756] synonym: "EHK1" EXACT [UniProtKB:P54756] synonym: "HEK7" EXACT [UniProtKB:P54756] xref: EMBL:AC018683 xref: EMBL:AC104137 xref: EMBL:AC105923 xref: EMBL:AC115223 xref: EMBL:L36644 xref: EMBL:X95425 xref: HGNC:HGNC:3389 xref: UniGene:Hs.654492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014944 ! EPHA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007495 name: EPHA6_human def: "Ephrin type-A receptor 6 precursor gene" [UniProtKB:Q9UF33] synonym: "EHK2" EXACT [UniProtKB:Q9UF33] xref: EMBL:AC107482 xref: EMBL:AC109782 xref: EMBL:AC117439 xref: EMBL:AC117470 xref: EMBL:AC119745 xref: EMBL:AC130510 xref: EMBL:AL133666 xref: HGNC:HGNC:19296 xref: UniGene:Hs.653244 xref: UniGene:Hs.653853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014941 ! EPHA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007496 name: EPHA7_human def: "Ephrin type-A receptor 7 precursor gene" [UniProtKB:Q15375] synonym: "EHK3" EXACT [UniProtKB:Q15375] synonym: "HEK11" EXACT [UniProtKB:Q15375] xref: EMBL:AB209269 xref: EMBL:AL121966 xref: EMBL:AL354857 xref: EMBL:AL591036 xref: EMBL:BC027940 xref: EMBL:BC126125 xref: EMBL:BC126151 xref: EMBL:L36642 xref: HGNC:HGNC:3390 xref: UniGene:Hs.73962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014961 ! EPHA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007497 name: EPHA8_human def: "Ephrin type-A receptor 8 precursor gene" [UniProtKB:P29322] synonym: "EEK" EXACT [UniProtKB:P29322] synonym: "KIAA1459" EXACT [UniProtKB:P29322] xref: EMBL:AB040892 xref: EMBL:AL035703 xref: EMBL:BC038796 xref: EMBL:BC072417 xref: EMBL:X59291 xref: HGNC:HGNC:3391 xref: UniGene:Hs.283613 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014957 ! EPHA8_HUMAN relationship: codes_for CCO:B0014963 ! Q8IUX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007498 name: EPHA10_human def: "Ephrin type-A receptor 10 precursor gene" [UniProtKB:Q5JZY3] xref: EMBL:AJ781169 xref: EMBL:AJ872185 xref: EMBL:BC067734 xref: HGNC:HGNC:19987 xref: UniGene:Hs.129435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014946 ! EPHAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007499 name: EPHB1_human def: "Ephrin type-B receptor 1 precursor gene" [UniProtKB:P54762] synonym: "EPHT2" EXACT [UniProtKB:P54762] synonym: "NET" EXACT [UniProtKB:P54762] xref: EMBL:AF037331 xref: EMBL:AF037332 xref: EMBL:AF037333 xref: EMBL:AF037334 xref: EMBL:L40636 xref: HGNC:HGNC:3392 xref: UniGene:Hs.116092 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014969 ! EPHB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007500 name: EPHB3_human def: "Ephrin type-B receptor 3 precursor gene" [UniProtKB:P54753] synonym: "ETK2" EXACT [UniProtKB:P54753] synonym: "HEK2" EXACT [UniProtKB:P54753] synonym: "TYRO6" EXACT [UniProtKB:P54753] xref: EMBL:BC052968 xref: EMBL:X75208 xref: HGNC:HGNC:3394 xref: UniGene:Hs.2913 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014968 ! EPHB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007501 name: ERCC1_human def: "DNA excision repair protein ERCC-1 gene" [UniProtKB:P07992] xref: EMBL:AF001925 xref: EMBL:AF512555 xref: EMBL:BC008930 xref: EMBL:BT019806 xref: EMBL:M13194 xref: EMBL:M26163 xref: EMBL:M28650 xref: HGNC:HGNC:3433 xref: UniGene:Hs.435981 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015646 ! ERCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007507 name: ETV6_human def: "Transcription factor ETV6 gene" [UniProtKB:P41212] synonym: "TEL" EXACT [UniProtKB:P41212] synonym: "TEL1" EXACT [UniProtKB:P41212] xref: EMBL:BC043399 xref: EMBL:DQ841178 xref: EMBL:U11732 xref: EMBL:U61375 xref: EMBL:U63312 xref: EMBL:U63313 xref: HGNC:HGNC:3495 xref: UniGene:Hs.504765 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028354 ! ETV6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007508 name: EVI5L_human def: "EVI5-like protein gene" [UniProtKB:Q96CN4] xref: EMBL:BC014111 xref: HGNC:HGNC:30464 xref: UniGene:Hs.26870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018142 ! EVI5L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007513 name: PFKFB1_human def: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 gene" [UniProtKB:P16118] synonym: "F6PK" EXACT [UniProtKB:P16118] synonym: "PFRX" EXACT [UniProtKB:P16118] xref: EMBL:AL020991 xref: EMBL:AL049732 xref: EMBL:BC096079 xref: EMBL:M19938 xref: EMBL:X52638 xref: HGNC:HGNC:8872 xref: UniGene:Hs.444304 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033471 ! F261_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007519 name: FABP4_human def: "Fatty acid-binding protein, adipocyte gene" [UniProtKB:P15090] xref: EMBL:BC003672 xref: EMBL:BT006809 xref: EMBL:J02874 xref: HGNC:HGNC:3559 xref: UniGene:Hs.391561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034068 ! FABP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007521 name: FABP7_human def: "Fatty acid-binding protein, brain gene" [UniProtKB:O15540] synonym: "BLBP" EXACT [UniProtKB:O15540] synonym: "FABPB" EXACT [UniProtKB:O15540] synonym: "MRG" EXACT [UniProtKB:O15540] xref: EMBL:AJ002962 xref: EMBL:AL645811 xref: EMBL:BC012299 xref: EMBL:CR457057 xref: EMBL:D50373 xref: EMBL:D88648 xref: EMBL:U51338 xref: EMBL:U81235 xref: HGNC:HGNC:3562 xref: UniGene:Hs.26770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034060 ! FABP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007523 name: FABP3_human def: "Fatty acid-binding protein, heart gene" [UniProtKB:P05413] synonym: "FABP11" EXACT [UniProtKB:P05413] synonym: "MDGI" EXACT [UniProtKB:P05413] xref: EMBL:AL451070 xref: EMBL:BC007021 xref: EMBL:BT006727 xref: EMBL:S67314 xref: EMBL:U17081 xref: EMBL:U57623 xref: EMBL:X56549 xref: EMBL:Y10255 xref: HGNC:HGNC:3557 xref: UniGene:Hs.657242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034070 ! FABPH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007526 name: FBLIM1_human def: "Filamin-binding LIM protein 1 gene" [UniProtKB:Q8WUP2] synonym: "FBLP1" EXACT [UniProtKB:Q8WUP2] xref: EMBL:AF459643 xref: EMBL:AK027444 xref: EMBL:AK055259 xref: EMBL:AL133035 xref: EMBL:AL450998 xref: EMBL:AY180161 xref: EMBL:BC019895 xref: HGNC:HGNC:24686 xref: UniGene:Hs.530101 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031065 ! FBLI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007527 name: FBXO8_human def: "F-box only protein 8 gene" [UniProtKB:Q9NRD0] synonym: "DC10" EXACT [UniProtKB:Q9NRD0] synonym: "FBS" EXACT [UniProtKB:Q9NRD0] synonym: "FBX8" EXACT [UniProtKB:Q9NRD0] synonym: "UNQ1877/PRO4320" EXACT [UniProtKB:Q9NRD0] xref: EMBL:AF174596 xref: EMBL:AF201932 xref: EMBL:AF233224 xref: EMBL:AY358721 xref: EMBL:BC014679 xref: EMBL:BC040456 xref: HGNC:HGNC:13587 xref: UniGene:Hs.76917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032438 ! FBX8_HUMAN relationship: codes_for CCO:B0032439 ! Q8IWE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007528 name: MS4A2_human def: "High affinity immunoglobulin epsilon receptor subunit beta gene" [UniProtKB:Q01362] synonym: "APY" EXACT [UniProtKB:Q01362] synonym: "FCER1B" EXACT [UniProtKB:Q01362] synonym: "IGER" EXACT [UniProtKB:Q01362] xref: EMBL:BC074800 xref: EMBL:BC074843 xref: EMBL:D10583 xref: EMBL:M89796 xref: HGNC:HGNC:7316 xref: UniGene:Hs.386748 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016650 ! FCERB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007529 name: FDFT1_human def: "Squalene synthetase gene" [UniProtKB:P37268] xref: EMBL:BC003573 xref: EMBL:BC009251 xref: EMBL:BC029641 xref: EMBL:L06070 xref: EMBL:L06105 xref: EMBL:S76822 xref: EMBL:X69141 xref: HGNC:HGNC:3629 xref: UniGene:Hs.593928 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027270 ! FDFT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007531 name: FN1_human def: "Fibronectin precursor gene" [UniProtKB:P02751] synonym: "FN" EXACT [UniProtKB:P02751] xref: EMBL:AB191261 xref: EMBL:AB209840 xref: EMBL:AC012462 xref: EMBL:AF312399 xref: EMBL:AJ276395 xref: EMBL:AJ320525 xref: EMBL:AJ320526 xref: EMBL:AJ320527 xref: EMBL:AJ535086 xref: EMBL:AL832202 xref: EMBL:BC117176 xref: EMBL:BX537590 xref: EMBL:BX538017 xref: EMBL:BX538018 xref: EMBL:BX640608 xref: EMBL:BX640731 xref: EMBL:BX640875 xref: EMBL:CR749281 xref: EMBL:CR749316 xref: EMBL:CR749317 xref: EMBL:M10905 xref: EMBL:M12549 xref: EMBL:M14059 xref: EMBL:M15801 xref: EMBL:M18177 xref: EMBL:M18178 xref: EMBL:M18179 xref: EMBL:M27589 xref: EMBL:U41850 xref: EMBL:U42404 xref: EMBL:U42455 xref: EMBL:U42456 xref: EMBL:U42457 xref: EMBL:U42458 xref: EMBL:U42592 xref: EMBL:U42593 xref: EMBL:U42594 xref: EMBL:X02761 xref: EMBL:X04530 xref: EMBL:X07717 xref: EMBL:X07718 xref: HGNC:HGNC:3778 xref: UniGene:Hs.203717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031949 ! FINC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007532 name: FOXA1_human def: "Hepatocyte nuclear factor 3-alpha gene" [UniProtKB:P55317] synonym: "HNF3A" EXACT [UniProtKB:P55317] synonym: "TCF3A" EXACT [UniProtKB:P55317] xref: EMBL:AF176111 xref: EMBL:AF176112 xref: EMBL:AF303742 xref: EMBL:AF303743 xref: EMBL:BC033890 xref: EMBL:U39840 xref: HGNC:HGNC:5021 xref: UniGene:Hs.163484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031624 ! FOXA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007533 name: FOXA2_human def: "Forkhead box A2 (Forkhead box A2, isoform CRA_b) gene" [UniProtKB:B0ZTD4] synonym: "hCG_22162" EXACT [UniProtKB:B0ZTD4] xref: EMBL:CH471133 xref: EMBL:EU402966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041586 ! B0ZTD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007534 name: FOXA3_human def: "Hepatocyte nuclear factor 3-gamma gene" [UniProtKB:P55318] synonym: "HNF3G" EXACT [UniProtKB:P55318] synonym: "TCF3G" EXACT [UniProtKB:P55318] xref: EMBL:AF176113 xref: EMBL:AF176114 xref: EMBL:AK223473 xref: EMBL:BC016024 xref: EMBL:BT006720 xref: EMBL:CH471126 xref: EMBL:EU275778 xref: EMBL:L12141 xref: HGNC:HGNC:5023 xref: UniGene:Hs.36137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031625 ! FOXA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007536 name: FOXB2_human def: "Forkhead box protein B2 gene" [UniProtKB:Q5VYV0] xref: EMBL:AL353637 xref: HGNC:HGNC:23315 xref: UniGene:Hs.553843 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016714 ! FOXB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007537 name: FOXC2_human def: "Forkhead box protein C2 gene" [UniProtKB:Q99958] synonym: "FKHL14" EXACT [UniProtKB:Q99958] synonym: "MFH1" EXACT [UniProtKB:Q99958] xref: EMBL:BC113437 xref: EMBL:BC113439 xref: EMBL:Y08223 xref: HGNC:HGNC:3801 xref: UniGene:Hs.436448 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016732 ! FOXC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007538 name: FOXD1_human def: "Forkhead box protein D1 gene" [UniProtKB:Q16676] synonym: "FKHL8" EXACT [UniProtKB:Q16676] synonym: "FREAC4" EXACT [UniProtKB:Q16676] xref: EMBL:U13222 xref: EMBL:U59831 xref: EMBL:U59832 xref: HGNC:HGNC:3802 xref: UniGene:Hs.519385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016706 ! FOXD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007539 name: FOXD2_human def: "Forkhead box protein D2 gene" [UniProtKB:O60548] synonym: "FKHL17" EXACT [UniProtKB:O60548] synonym: "FREAC9" EXACT [UniProtKB:O60548] xref: EMBL:AF042832 xref: EMBL:AL607122 xref: HGNC:HGNC:3803 xref: UniGene:Hs.166188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016696 ! FOXD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007540 name: FOXD3_human def: "Forkhead box protein D3 gene" [UniProtKB:Q9UJU5] synonym: "HFH2" EXACT [UniProtKB:Q9UJU5] xref: EMBL:AF197560 xref: EMBL:AL049636 xref: EMBL:L12142 xref: HGNC:HGNC:3804 xref: UniGene:Hs.546573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016733 ! FOXD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007541 name: FOXD4_human def: "FOXD4 gene" [UniProtKB:Q6VB86] xref: EMBL:AY344640 xref: HGNC:HGNC:3805 xref: UniGene:Hs.584759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016703 ! Q6VB86_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007542 name: FOXE1_human def: "Forkhead box protein E1 gene" [UniProtKB:O00358] synonym: "FKHL15" EXACT [UniProtKB:O00358] synonym: "FOXE2" EXACT [UniProtKB:O00358] synonym: "TITF2" EXACT [UniProtKB:O00358] synonym: "TTF2" EXACT [UniProtKB:O00358] xref: EMBL:AL499604 xref: EMBL:CH471105 xref: EMBL:U89995 xref: EMBL:X94553 xref: EMBL:Y13386 xref: HGNC:HGNC:3806 xref: HGNC:HGNC:3807 xref: UniGene:Hs.159234 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016695 ! FOXE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007543 name: FOXE3_human def: "Forkhead box protein E3 gene" [UniProtKB:Q13461] synonym: "FKHL12" EXACT [UniProtKB:Q13461] synonym: "FREAC8" EXACT [UniProtKB:Q13461] xref: EMBL:AF275722 xref: EMBL:AL607122 xref: EMBL:U42990 xref: HGNC:HGNC:3808 xref: UniGene:Hs.112968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016727 ! FOXE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007544 name: FOXF1_human def: "Forkhead box protein F1 gene" [UniProtKB:Q12946] synonym: "FKHL5" EXACT [UniProtKB:Q12946] synonym: "FREAC1" EXACT [UniProtKB:Q12946] xref: EMBL:AF085342 xref: EMBL:AF085343 xref: EMBL:BC089442 xref: EMBL:U13219 xref: HGNC:HGNC:3809 xref: UniGene:Hs.155591 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016699 ! FOXF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007545 name: FOXF2_human def: "Forkhead box protein F2 gene" [UniProtKB:Q12947] synonym: "FKHL6" EXACT [UniProtKB:Q12947] synonym: "FREAC2" EXACT [UniProtKB:Q12947] xref: EMBL:AF084938 xref: EMBL:AF084939 xref: EMBL:U13220 xref: HGNC:HGNC:3810 xref: UniGene:Hs.484423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016719 ! FOXF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007546 name: FOXG1_human def: "Forkhead box protein G1 gene" [UniProtKB:P55316] synonym: "FKH2" EXACT [UniProtKB:P55316] synonym: "FKHL1" EXACT [UniProtKB:P55316] synonym: "FKHL2" EXACT [UniProtKB:P55316] synonym: "FKHL3" EXACT [UniProtKB:P55316] synonym: "FKHL4" EXACT [UniProtKB:P55316] synonym: "FOXG1A" EXACT [UniProtKB:P55316] synonym: "FOXG1B" EXACT [UniProtKB:P55316] synonym: "FOXG1C" EXACT [UniProtKB:P55316] xref: EMBL:AL049777 xref: EMBL:BC050072 xref: EMBL:CH471078 xref: EMBL:X74142 xref: EMBL:X74143 xref: EMBL:X74144 xref: EMBL:X78202 xref: HGNC:HGNC:3811 xref: UniGene:Hs.695962 xref: UniGene:Hs.701530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016740 ! FOXG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007547 name: FOXI1_human def: "Forkhead box protein I1 gene" [UniProtKB:Q12951] synonym: "FKHL10" EXACT [UniProtKB:Q12951] synonym: "FREAC6" EXACT [UniProtKB:Q12951] xref: EMBL:AY707089 xref: EMBL:BC029778 xref: EMBL:L13203 xref: EMBL:U13224 xref: HGNC:HGNC:3815 xref: UniGene:Hs.87236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016694 ! FOXI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007548 name: FOXL1_human def: "Forkhead box protein L1 gene" [UniProtKB:Q12952] synonym: "FKHL11" EXACT [UniProtKB:Q12952] synonym: "FREAC7" EXACT [UniProtKB:Q12952] xref: EMBL:AF315075 xref: EMBL:BC117226 xref: EMBL:U13225 xref: HGNC:HGNC:3817 xref: UniGene:Hs.533830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016722 ! FOXL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007549 name: FOXL2_human def: "Transcription factor FOXL2 mutant 1 gene" [UniProtKB:Q4JHB7] xref: EMBL:DQ089670 xref: HGNC:HGNC:1092 xref: UniGene:Hs.289292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016702 ! Q4JHB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007550 name: FOXN2_human def: "Forkhead box protein N2 gene" [UniProtKB:P32314] synonym: "HTLF" EXACT [UniProtKB:P32314] xref: EMBL:AC091485 xref: EMBL:BC063305 xref: EMBL:U57029 xref: HGNC:HGNC:5281 xref: UniGene:Hs.468478 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015066 ! FOXN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007551 name: FOXO1_human def: "Forkhead box protein O1 gene" [UniProtKB:Q12778] synonym: "FKHR" EXACT [UniProtKB:Q12778] synonym: "FOXO1A" EXACT [UniProtKB:Q12778] xref: EMBL:AF032885 xref: EMBL:AL133318 xref: EMBL:AL355132 xref: EMBL:BC021981 xref: EMBL:BC070065 xref: EMBL:BT007455 xref: EMBL:U02310 xref: HGNC:HGNC:3819 xref: UniGene:Hs.370666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016881 ! FOXO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007552 name: FOXO6_human def: "Forkhead box protein O6 gene" [UniProtKB:A8MYZ6] xref: EMBL:AC093151 xref: HGNC:HGNC:24814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033027 ! FOXO6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007553 name: FOXQ1_human def: "Forkhead box protein Q1 gene" [UniProtKB:Q9C009] synonym: "HFH1" EXACT [UniProtKB:Q9C009] xref: EMBL:AF153341 xref: EMBL:AF225950 xref: EMBL:BC053850 xref: HGNC:HGNC:20951 xref: UniGene:Hs.591352 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016715 ! FOXQ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007554 name: FPR1_human def: "fMet-Leu-Phe receptor gene" [UniProtKB:P21462] xref: EMBL:AC018755 xref: EMBL:AY301273 xref: EMBL:BC005315 xref: EMBL:BT007429 xref: EMBL:L10820 xref: EMBL:M37128 xref: EMBL:M60626 xref: EMBL:M60627 xref: EMBL:S49810 xref: HGNC:HGNC:3826 xref: UniGene:Hs.753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027200 ! FPR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007558 name: FTH1_human def: "Ferritin heavy chain gene" [UniProtKB:P02794] synonym: "FTH" EXACT [UniProtKB:P02794] synonym: "FTHL6" EXACT [UniProtKB:P02794] synonym: "OK/SW-cl.84" EXACT [UniProtKB:P02794] synonym: "PIG15" EXACT [UniProtKB:P02794] xref: EMBL:AB062402 xref: EMBL:AF088851 xref: EMBL:AY258285 xref: EMBL:BC000857 xref: EMBL:BC001399 xref: EMBL:BC011359 xref: EMBL:BC013724 xref: EMBL:BC015156 xref: EMBL:BC016009 xref: EMBL:BC016857 xref: EMBL:BC063514 xref: EMBL:BC066961 xref: EMBL:BC073750 xref: EMBL:BC104643 xref: EMBL:BC105802 xref: EMBL:DQ496108 xref: EMBL:L20941 xref: EMBL:M11146 xref: EMBL:M12937 xref: EMBL:M14211 xref: EMBL:M14212 xref: EMBL:M15383 xref: EMBL:M97164 xref: EMBL:X00318 xref: EMBL:X03487 xref: EMBL:X03488 xref: HGNC:HGNC:3976 xref: UniGene:Hs.524910 xref: UniGene:Hs.645560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033704 ! FRIH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007560 name: FOXD4L1_human def: "Forkhead box protein D4-like 1 gene" [UniProtKB:Q9NU39] xref: EMBL:AF452723 xref: EMBL:AL078621 xref: EMBL:AY344639 xref: HGNC:HGNC:18521 xref: UniGene:Hs.698326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016708 ! FX4L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007561 name: FOXD4L2_human def: "Forkhead box protein D4-like 2 gene" [UniProtKB:Q6VB85] xref: EMBL:AY344641 xref: HGNC:HGNC:24813 xref: UniGene:Hs.449471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031623 ! FX4L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007562 name: FOXD4L3_human def: "Forkhead box protein D4-like 3 gene" [UniProtKB:Q6VB84] xref: EMBL:AY344642 xref: HGNC:HGNC:18523 xref: UniGene:Hs.449471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016737 ! FX4L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007563 name: FOXD4L4_human def: "Forkhead box protein D4-like 4 gene" [UniProtKB:Q8WXT5] synonym: "FOXD4B" EXACT [UniProtKB:Q8WXT5] xref: EMBL:AF343005 xref: EMBL:BX284632 xref: HGNC:HGNC:23762 xref: UniGene:Hs.534644 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016698 ! FX4L4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007564 name: FOXD4L5_human def: "Forkhead box protein D4-like 5 gene" [UniProtKB:Q5VV16] xref: EMBL:AL512605 xref: HGNC:HGNC:18522 xref: UniGene:Hs.449471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016720 ! FX4L5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007565 name: FOXD4L6_human def: "Forkhead box protein D4-like 6 gene" [UniProtKB:Q3SYB3] xref: EMBL:BC103887 xref: EMBL:BX255923 xref: HGNC:HGNC:31986 xref: UniGene:Hs.652377 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016724 ! FX4L6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007569 name: G3BP1_human def: "Ras GTPase-activating protein-binding protein 1 gene" [UniProtKB:Q13283] synonym: "G3BP" EXACT [UniProtKB:Q13283] xref: EMBL:BC006997 xref: EMBL:U32519 xref: HGNC:HGNC:30292 xref: UniGene:Hs.587054 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028328 ! G3BP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007570 name: G3BP2_human def: "Ras GTPase-activating protein-binding protein 2 gene" [UniProtKB:Q9UN86] synonym: "KIAA0660" EXACT [UniProtKB:Q9UN86] xref: EMBL:AB014560 xref: EMBL:AF051311 xref: EMBL:AF053535 xref: EMBL:AF145284 xref: EMBL:BC011731 xref: HGNC:HGNC:30291 xref: UniGene:Hs.303676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028327 ! G3BP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007579 name: GAGE5_human def: "G antigen 5 gene" [UniProtKB:Q13069] xref: EMBL:BC024914 xref: EMBL:CR542236 xref: EMBL:U19146 xref: HGNC:HGNC:4102 xref: UniGene:Hs.460641 xref: UniGene:Hs.632815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033870 ! GAGE5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007582 name: GAGE8_human def: "G antigen 8 gene" [UniProtKB:Q9UEU5] xref: EMBL:AF055473 xref: EMBL:BC018052 xref: EMBL:BX649339 xref: HGNC:HGNC:4106 xref: UniGene:Hs.668804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033871 ! GAGE8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007583 name: GAS6_human def: "Growth arrest-specific protein 6 precursor gene" [UniProtKB:Q14393] synonym: "AXLLG" EXACT [UniProtKB:Q14393] xref: EMBL:AK126533 xref: EMBL:AK290803 xref: EMBL:AY170372 xref: EMBL:AY256830 xref: EMBL:AY256831 xref: EMBL:AY256832 xref: EMBL:AY256833 xref: EMBL:AY256834 xref: EMBL:AY256835 xref: EMBL:AY256836 xref: EMBL:AY256837 xref: EMBL:AY256838 xref: EMBL:AY256839 xref: EMBL:AY256840 xref: EMBL:AY256841 xref: EMBL:AY256842 xref: EMBL:AY256843 xref: EMBL:BC038984 xref: EMBL:BK001240 xref: EMBL:BX072579 xref: EMBL:EF631974 xref: EMBL:L13720 xref: HGNC:HGNC:4168 xref: UniGene:Hs.646346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034258 ! GAS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007591 name: GHRL_human def: "Appetite-regulating hormone precursor gene" [UniProtKB:Q9UBU3] synonym: "MTLRP" EXACT [UniProtKB:Q9UBU3] synonym: "UNQ524/PRO1066" EXACT [UniProtKB:Q9UBU3] xref: EMBL:AB029434 xref: EMBL:AB035700 xref: EMBL:AF296558 xref: EMBL:AJ252278 xref: EMBL:AY359053 xref: EMBL:BC025791 xref: HGNC:HGNC:18129 xref: UniGene:Hs.590080 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033567 ! GHRL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007597 name: GLIS1_human def: "Zinc finger protein GLIS1 gene" [UniProtKB:Q8NBF1] xref: EMBL:AC105280 xref: EMBL:AK090634 xref: EMBL:AK093474 xref: EMBL:AL591720 xref: EMBL:BC101799 xref: EMBL:BC104911 xref: EMBL:CH471059 xref: HGNC:HGNC:29525 xref: UniGene:Hs.306691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020932 ! GLIS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007598 name: BLZF1_human def: "Golgin-45 gene" [UniProtKB:Q9H2G9] synonym: "JEM1" EXACT [UniProtKB:Q9H2G9] xref: EMBL:AF272386 xref: EMBL:AF272387 xref: EMBL:AF272388 xref: EMBL:AF273875 xref: EMBL:AF288161 xref: EMBL:AF288162 xref: EMBL:AL356852 xref: EMBL:BC020716 xref: EMBL:U79751 xref: HGNC:HGNC:1065 xref: UniGene:Hs.130746 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028029 ! GO45_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007600 name: GPR112_human def: "Probable G-protein coupled receptor 112 gene" [UniProtKB:Q8IZF6] xref: EMBL:AL078638 xref: EMBL:AL136167 xref: EMBL:AL161778 xref: EMBL:AY140954 xref: EMBL:AY255581 xref: EMBL:AY882585 xref: HGNC:HGNC:18992 xref: UniGene:Hs.381354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033406 ! A2A2J1_HUMAN relationship: codes_for CCO:B0033407 ! A2A2J2_HUMAN relationship: codes_for CCO:B0033412 ! GP112_HUMAN relationship: codes_for CCO:B0033415 ! Q5EGP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007601 name: GPR126_human def: "Probable G-protein coupled receptor 126 precursor gene" [UniProtKB:Q86SQ4] xref: EMBL:AB183548 xref: EMBL:AK027843 xref: EMBL:AK075087 xref: EMBL:AL033377 xref: EMBL:AL360007 xref: EMBL:AY181244 xref: EMBL:AY426673 xref: EMBL:BX640873 xref: EMBL:BX640971 xref: HGNC:HGNC:13841 xref: UniGene:Hs.318894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033404 ! Q6F3F6_HUMAN relationship: codes_for CCO:B0033405 ! GP126_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007602 name: GPR64_human def: "G-protein coupled receptor 64 precursor gene" [UniProtKB:Q8IZP9] synonym: "HE6" EXACT [UniProtKB:Q8IZP9] synonym: "TM7LN2" EXACT [UniProtKB:Q8IZP9] xref: EMBL:AF538954 xref: EMBL:AF539455 xref: EMBL:AF539456 xref: EMBL:AL732509 xref: EMBL:AL732578 xref: EMBL:AY143364 xref: EMBL:AY143365 xref: EMBL:AY143366 xref: EMBL:AY143367 xref: EMBL:AY148343 xref: EMBL:BC099901 xref: EMBL:BC113979 xref: EMBL:X81892 xref: HGNC:HGNC:4516 xref: UniGene:Hs.146978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033402 ! Q14CE0_HUMAN relationship: codes_for CCO:B0033410 ! A9Z1X2_HUMAN relationship: codes_for CCO:B0033414 ! Q499H0_HUMAN relationship: codes_for CCO:B0033418 ! GPR64_HUMAN relationship: codes_for CCO:B0054278 ! B1AWB3_HUMAN relationship: codes_for CCO:B0054279 ! B1AWB4_HUMAN relationship: codes_for CCO:B0054280 ! B1AWB6_HUMAN relationship: codes_for CCO:B0054281 ! B1AWB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007606 name: GCA_human def: "Grancalcin gene" [UniProtKB:P28676] synonym: "GCL" EXACT [UniProtKB:P28676] xref: EMBL:AB209768 xref: EMBL:AC010876 xref: EMBL:BC005214 xref: EMBL:M81637 xref: HGNC:HGNC:15990 xref: UniGene:Hs.377894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026105 ! GRAN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007608 name: GSK3B_human def: "Glycogen synthase kinase-3 beta gene" [UniProtKB:P49841] xref: EMBL:AF074333 xref: EMBL:AF098789 xref: EMBL:BC000251 xref: EMBL:BC012760 xref: EMBL:L33801 xref: HGNC:HGNC:4617 xref: UniGene:Hs.445733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016826 ! GSK3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007609 name: GTPBP1_human def: "GTP-binding protein 1 gene" [UniProtKB:O00178] xref: EMBL:AL021707 xref: EMBL:BC014075 xref: EMBL:CR456501 xref: EMBL:U87964 xref: HGNC:HGNC:4669 xref: UniGene:Hs.276925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020855 ! GTPB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007611 name: GUCY2C_human def: "Heat-stable enterotoxin receptor precursor gene" [UniProtKB:P25092] synonym: "GUC2C" EXACT [UniProtKB:P25092] synonym: "STAR" EXACT [UniProtKB:P25092] xref: EMBL:M73489 xref: EMBL:S57551 xref: EMBL:U20230 xref: HGNC:HGNC:4688 xref: UniGene:Hs.524278 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016685 ! GUC2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007612 name: GUCY2D_human def: "Retinal guanylyl cyclase 1 precursor gene" [UniProtKB:Q02846] synonym: "CORD6" EXACT [UniProtKB:Q02846] synonym: "GUC1A4" EXACT [UniProtKB:Q02846] synonym: "GUC2D" EXACT [UniProtKB:Q02846] synonym: "RETGC" EXACT [UniProtKB:Q02846] synonym: "RETGC1" EXACT [UniProtKB:Q02846] xref: EMBL:AJ222657 xref: EMBL:L26921 xref: EMBL:M92432 xref: HGNC:HGNC:4689 xref: UniGene:Hs.592109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016682 ! GUC2D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007613 name: GUCY2F_human def: "Retinal guanylyl cyclase 2 precursor gene" [UniProtKB:P51841] synonym: "GUC2F" EXACT [UniProtKB:P51841] synonym: "RETGC2" EXACT [UniProtKB:P51841] xref: EMBL:AL031387 xref: EMBL:L37378 xref: HGNC:HGNC:4691 xref: UniGene:Hs.123074 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016684 ! GUC2F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007615 name: HBEGF_human def: "Proheparin-binding EGF-like growth factor precursor gene" [UniProtKB:Q99075] synonym: "DTR" EXACT [UniProtKB:Q99075] synonym: "DTS" EXACT [UniProtKB:Q99075] synonym: "HEGFL" EXACT [UniProtKB:Q99075] xref: EMBL:AC004634 xref: EMBL:AY164533 xref: EMBL:BC033097 xref: EMBL:M60278 xref: HGNC:HGNC:3059 xref: UniGene:Hs.799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021671 ! HBEGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007616 name: ASCC3_human def: "Activating signal cointegrator 1 complex subunit 3 gene" [UniProtKB:Q8N3C0] synonym: "HELIC1" EXACT [UniProtKB:Q8N3C0] xref: EMBL:AJ223948 xref: EMBL:AL121965 xref: EMBL:AL133338 xref: EMBL:AL356122 xref: EMBL:AL591585 xref: EMBL:AL834463 xref: EMBL:AY013288 xref: EMBL:Z86062 xref: HGNC:HGNC:18697 xref: UniGene:Hs.486031 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020998 ! HELC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007620 name: HIC2_human def: "Hypermethylated in cancer 2 protein gene" [UniProtKB:Q96JB3] synonym: "HRG22" EXACT [UniProtKB:Q96JB3] synonym: "KIAA1020" EXACT [UniProtKB:Q96JB3] synonym: "ZBTB30" EXACT [UniProtKB:Q96JB3] xref: EMBL:AB028943 xref: EMBL:AF349035 xref: EMBL:AJ313204 xref: EMBL:AL162003 xref: EMBL:AP000557 xref: EMBL:BC094787 xref: EMBL:CR456377 xref: HGNC:HGNC:18595 xref: UniGene:Hs.592456 xref: UniGene:Hs.632767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023371 ! HIC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007624 name: HIRA_human def: "Protein HIRA gene" [UniProtKB:P54198] synonym: "DGCR1" EXACT [UniProtKB:P54198] synonym: "HIR" EXACT [UniProtKB:P54198] synonym: "TUPLE1" EXACT [UniProtKB:P54198] xref: EMBL:BC032721 xref: EMBL:BC039835 xref: EMBL:CR456503 xref: EMBL:X75296 xref: EMBL:X77633 xref: EMBL:X81844 xref: EMBL:X89887 xref: EMBL:X91501 xref: HGNC:HGNC:4916 xref: UniGene:Hs.474206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016028 ! HIRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007631 name: HSPA1L_human def: "Heat shock 70 kDa protein 1L gene" [UniProtKB:P34931] xref: EMBL:AF134726 xref: EMBL:AL662834 xref: EMBL:AL671762 xref: EMBL:AL929592 xref: EMBL:BA000025 xref: EMBL:BC034483 xref: EMBL:D85730 xref: EMBL:DQ383515 xref: EMBL:M59829 xref: HGNC:HGNC:5234 xref: UniGene:Hs.690634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023825 ! HS71L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007632 name: HSF1_human def: "Heat shock factor protein 1 gene" [UniProtKB:Q00613] synonym: "HSTF1" EXACT [UniProtKB:Q00613] xref: EMBL:BC014638 xref: EMBL:BT007351 xref: EMBL:M64673 xref: HGNC:HGNC:5224 xref: UniGene:Hs.530227 xref: UniGene:Hs.571397 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026467 ! HSF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007633 name: HSF2_human def: "Heat shock factor protein 2 gene" [UniProtKB:Q03933] synonym: "HSTF2" EXACT [UniProtKB:Q03933] xref: EMBL:AL121954 xref: EMBL:BC112323 xref: EMBL:BC121051 xref: EMBL:DQ492684 xref: EMBL:M65217 xref: EMBL:Z99129 xref: HGNC:HGNC:5225 xref: UniGene:Hs.158195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026489 ! HSF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007634 name: HSPA6_human def: "Heat shock 70 kDa protein 6 gene" [UniProtKB:P17066] synonym: "HSP70B'" EXACT [UniProtKB:P17066] xref: EMBL:BC004279 xref: EMBL:BC035665 xref: EMBL:S78631 xref: EMBL:X51757 xref: EMBL:X51758 xref: HGNC:HGNC:5239 xref: UniGene:Hs.654614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023839 ! HSP76_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007635 name: HSPB8_human def: "Heat shock protein beta-8 gene" [UniProtKB:Q9UJY1] synonym: "CRYAC" EXACT [UniProtKB:Q9UJY1] synonym: "E2IG1" EXACT [UniProtKB:Q9UJY1] synonym: "HSP22" EXACT [UniProtKB:Q9UJY1] synonym: "PP1629" EXACT [UniProtKB:Q9UJY1] xref: EMBL:AF133207 xref: EMBL:AF191017 xref: EMBL:AF217987 xref: EMBL:AF250138 xref: EMBL:AL136936 xref: EMBL:BC002673 xref: EMBL:BT006876 xref: EMBL:CR533453 xref: HGNC:HGNC:30171 xref: UniGene:Hs.400095 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024107 ! HSPB8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007637 name: IL12RB2_human def: "Interleukin-12 receptor beta-2 chain precursor gene" [UniProtKB:Q99665] xref: EMBL:AY640177 xref: EMBL:BC104772 xref: EMBL:BC104774 xref: EMBL:U64198 xref: HGNC:HGNC:5972 xref: UniGene:Hs.479347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034147 ! I12R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007638 name: IL17RA_human def: "Interleukin-17 receptor A precursor gene" [UniProtKB:Q96F46] synonym: "IL17R" EXACT [UniProtKB:Q96F46] xref: EMBL:BC011624 xref: EMBL:U58917 xref: HGNC:HGNC:5985 xref: UniGene:Hs.129751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032298 ! I17RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007639 name: IL17RB_human def: "Interleukin-17 receptor B precursor gene" [UniProtKB:Q9NRM6] synonym: "EVI27" EXACT [UniProtKB:Q9NRM6] synonym: "IL17BR" EXACT [UniProtKB:Q9NRM6] synonym: "UNQ2501/PRO19612" EXACT [UniProtKB:Q9NRM6] xref: EMBL:AF208110 xref: EMBL:AF208111 xref: EMBL:AF212365 xref: EMBL:AF250309 xref: EMBL:AY359122 xref: EMBL:AY518533 xref: EMBL:BC000980 xref: HGNC:HGNC:18015 xref: UniGene:Hs.654970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021887 ! I17RB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007641 name: EIF2C1_human def: "Eukaryotic translation initiation factor 2C 1 gene" [UniProtKB:Q9UL18] synonym: "AGO1" EXACT [UniProtKB:Q9UL18] xref: EMBL:AF093097 xref: EMBL:AL139286 xref: EMBL:BC063275 xref: HGNC:HGNC:3262 xref: UniGene:Hs.22867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016057 ! I2C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007642 name: EIF2C2_human def: "Eukaryotic translation initiation factor 2C 2 gene" [UniProtKB:Q9UKV8] synonym: "AGO2" EXACT [UniProtKB:Q9UKV8] xref: EMBL:AF121255 xref: EMBL:AY077717 xref: EMBL:BC007633 xref: EMBL:BC018727 xref: EMBL:BT007229 xref: HGNC:HGNC:3263 xref: UniGene:Hs.705508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016049 ! I2C2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007643 name: EIF2C3_human def: "Eukaryotic translation initiation factor 2C 3 gene" [UniProtKB:Q9H9G7] synonym: "AGO3" EXACT [UniProtKB:Q9H9G7] xref: EMBL:AK022827 xref: EMBL:AL138787 xref: EMBL:AL139286 xref: HGNC:HGNC:18421 xref: UniGene:Hs.657659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016054 ! I2C3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007644 name: EIF2C4_human def: "Eukaryotic translation initiation factor 2C 4 gene" [UniProtKB:Q9HCK5] synonym: "AGO4" EXACT [UniProtKB:Q9HCK5] synonym: "KIAA1567" EXACT [UniProtKB:Q9HCK5] xref: EMBL:AB046787 xref: HGNC:HGNC:18424 xref: UniGene:Hs.471492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016055 ! I2C4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007646 name: ICK_human def: "Serine/threonine-protein kinase ICK gene" [UniProtKB:Q9UPZ9] synonym: "KIAA0936" EXACT [UniProtKB:Q9UPZ9] xref: EMBL:AB023153 xref: EMBL:AF152469 xref: EMBL:AF225919 xref: EMBL:AL031178 xref: EMBL:AL162581 xref: EMBL:BC035807 xref: HGNC:HGNC:21219 xref: UniGene:Hs.417022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018166 ! ICK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007647 name: IDE_human def: "Insulin-degrading enzyme gene" [UniProtKB:P14735] xref: EMBL:AL356128 xref: EMBL:BC096336 xref: EMBL:BC096337 xref: EMBL:BC096339 xref: EMBL:CH471066 xref: EMBL:M21188 xref: HGNC:HGNC:5381 xref: UniGene:Hs.500546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030742 ! IDE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007655 name: IFNA2_human def: "Interferon alpha-2 precursor gene" [UniProtKB:P01563] xref: EMBL:A04970 xref: EMBL:J00207 xref: EMBL:M29883 xref: EMBL:M54886 xref: EMBL:V00544 xref: EMBL:V00548 xref: EMBL:V00549 xref: EMBL:Y11834 xref: HGNC:HGNC:5423 xref: UniGene:Hs.211575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015973 ! IFNA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007662 name: IFNG_human def: "Interferon gamma precursor gene" [UniProtKB:P01579] xref: EMBL:AF375790 xref: EMBL:BC070256 xref: EMBL:J00219 xref: EMBL:V00543 xref: EMBL:X01992 xref: EMBL:X13274 xref: HGNC:HGNC:5438 xref: UniGene:Hs.856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031813 ! IFNG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007663 name: IFNK_human def: "Interferon kappa precursor gene" [UniProtKB:Q9P0W0] synonym: "UNQ6124/PRO20084" EXACT [UniProtKB:Q9P0W0] xref: EMBL:AF146759 xref: EMBL:AF315688 xref: EMBL:AF384048 xref: EMBL:AL451123 xref: EMBL:AY358855 xref: HGNC:HGNC:21714 xref: UniGene:Hs.591083 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015956 ! IFNK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007664 name: IGHG1_human def: "Ig gamma-1 chain C region gene" [UniProtKB:P01857] xref: EMBL:J00228 xref: HGNC:HGNC:5525 xref: UniGene:Hs.510635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034317 ! IGHG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007666 name: IGHG3_human def: "Ig gamma-3 chain C region gene" [UniProtKB:P01860] xref: EMBL:BC033178 xref: EMBL:J00231 xref: EMBL:X03604 xref: HGNC:HGNC:5527 xref: UniGene:Hs.510635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034291 ! IGHG3_HUMAN relationship: codes_for CCO:B0034304 ! Q8N4Y9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007670 name: CSF2RB_human def: "Cytokine receptor common subunit beta precursor gene" [UniProtKB:P32927] synonym: "IL3RB" EXACT [UniProtKB:P32927] synonym: "IL5RB" EXACT [UniProtKB:P32927] xref: EMBL:AL008637 xref: EMBL:AL133392 xref: EMBL:CH471095 xref: EMBL:CR456428 xref: EMBL:M59941 xref: HGNC:HGNC:2436 xref: UniGene:Hs.592192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025042 ! IL3RB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007671 name: IL6ST_human def: "Interleukin-6 receptor subunit beta precursor gene" [UniProtKB:P40189] xref: EMBL:AB015706 xref: EMBL:CH471123 xref: EMBL:EF064722 xref: EMBL:M57230 xref: HGNC:HGNC:6021 xref: UniGene:Hs.532082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025184 ! IL6RB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007672 name: IL7_human def: "Interleukin-7 precursor gene" [UniProtKB:P13232] xref: EMBL:BC047698 xref: EMBL:J04156 xref: EMBL:M29048 xref: EMBL:M29049 xref: EMBL:M29050 xref: EMBL:M29051 xref: EMBL:M29052 xref: EMBL:M29053 xref: HGNC:HGNC:6023 xref: UniGene:Hs.591873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024369 ! IL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007674 name: ING2_human def: "Inhibitor of growth protein 2 gene" [UniProtKB:Q9H160] synonym: "ING1L" EXACT [UniProtKB:Q9H160] xref: EMBL:AB012853 xref: EMBL:AF053537 xref: EMBL:AF062747 xref: EMBL:AF062748 xref: EMBL:AJ006851 xref: EMBL:BC030128 xref: HGNC:HGNC:6063 xref: UniGene:Hs.107153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017118 ! ING2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007676 name: IPO11_human def: "Importin-11 gene" [UniProtKB:Q9UI26] synonym: "RANBP11" EXACT [UniProtKB:Q9UI26] xref: EMBL:AC008859 xref: EMBL:AF111109 xref: EMBL:AK001696 xref: EMBL:AL162083 xref: EMBL:BC031694 xref: EMBL:BC033776 xref: EMBL:CH471137 xref: HGNC:HGNC:20628 xref: UniGene:Hs.482269 xref: UniGene:Hs.623985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024299 ! IPO11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007677 name: SERPINA5_human def: "Plasma serine protease inhibitor precursor gene" [UniProtKB:P05154] synonym: "PCI" EXACT [UniProtKB:P05154] synonym: "PLANH3" EXACT [UniProtKB:P05154] synonym: "PROCI" EXACT [UniProtKB:P05154] xref: EMBL:AF361796 xref: EMBL:AL080185 xref: EMBL:BC008915 xref: EMBL:J02639 xref: EMBL:M68516 xref: EMBL:S58545 xref: EMBL:S69364 xref: EMBL:S69365 xref: EMBL:S69366 xref: EMBL:S69574 xref: EMBL:U35464 xref: HGNC:HGNC:8723 xref: UniGene:Hs.510334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014899 ! IPSP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007678 name: IQGAP1_human def: "Ras GTPase-activating-like protein IQGAP1 gene" [UniProtKB:P46940] synonym: "KIAA0051" EXACT [UniProtKB:P46940] xref: EMBL:D29640 xref: EMBL:L33075 xref: HGNC:HGNC:6110 xref: UniGene:Hs.430551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018386 ! IQGA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007679 name: IQGAP2_human def: "Ras GTPase-activating-like protein IQGAP2 gene" [UniProtKB:Q13576] xref: EMBL:AY351902 xref: EMBL:U51903 xref: HGNC:HGNC:6111 xref: UniGene:Hs.291030 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018391 ! IQGA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007680 name: IQGAP3_human def: "Ras GTPase-activating-like protein IQGAP3 gene" [UniProtKB:Q86VI3] xref: EMBL:AB105103 xref: EMBL:AK122653 xref: EMBL:AY253300 xref: HGNC:HGNC:20669 xref: UniGene:Hs.591495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018395 ! IQGA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007682 name: ITGB1_human def: "Integrin beta-1 precursor gene" [UniProtKB:P05556] synonym: "FNRB" EXACT [UniProtKB:P05556] synonym: "MDF2" EXACT [UniProtKB:P05556] synonym: "MSK12" EXACT [UniProtKB:P05556] xref: EMBL:AL365203 xref: EMBL:BC020057 xref: EMBL:CH471072 xref: EMBL:M34189 xref: EMBL:M84237 xref: EMBL:U28252 xref: EMBL:U33879 xref: EMBL:U33880 xref: EMBL:U33881 xref: EMBL:U33882 xref: EMBL:X07979 xref: HGNC:HGNC:6153 xref: UniGene:Hs.695946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033131 ! Q5T3E5_HUMAN relationship: codes_for CCO:B0033136 ! Q8WUM6_HUMAN relationship: codes_for CCO:B0033138 ! ITB1_HUMAN relationship: codes_for CCO:B0033143 ! Q5T3E4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007683 name: ITGB2_human def: "Integrin beta-2 precursor gene" [UniProtKB:P05107] synonym: "CD18" EXACT [UniProtKB:P05107] synonym: "MFI7" EXACT [UniProtKB:P05107] xref: EMBL:AL163300 xref: EMBL:AL773603 xref: EMBL:BC005861 xref: EMBL:M15395 xref: EMBL:S81234 xref: EMBL:X63924 xref: EMBL:X63925 xref: EMBL:X63926 xref: EMBL:X64072 xref: EMBL:X64073 xref: EMBL:X64074 xref: EMBL:X64075 xref: EMBL:X64076 xref: EMBL:X64077 xref: EMBL:X64078 xref: EMBL:X64079 xref: EMBL:X64080 xref: EMBL:X64081 xref: EMBL:X64082 xref: EMBL:X64083 xref: EMBL:Y00057 xref: HGNC:HGNC:6155 xref: UniGene:Hs.375957 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033122 ! ITB2_HUMAN relationship: codes_for CCO:B0033134 ! A8MYE6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007684 name: ITGB3_human def: "Integrin beta-3 precursor gene" [UniProtKB:P05106] synonym: "GP3A" EXACT [UniProtKB:P05106] xref: EMBL:BC127666 xref: EMBL:BC127667 xref: EMBL:J02703 xref: EMBL:L28832 xref: EMBL:M20311 xref: EMBL:M25108 xref: EMBL:M32667 xref: EMBL:M32672 xref: EMBL:M32673 xref: EMBL:M32674 xref: EMBL:M32675 xref: EMBL:M32680 xref: EMBL:M32681 xref: EMBL:M32682 xref: EMBL:M32685 xref: EMBL:M32686 xref: EMBL:M35999 xref: EMBL:M57481 xref: EMBL:M57482 xref: EMBL:M57483 xref: EMBL:M57484 xref: EMBL:M57485 xref: EMBL:M57486 xref: EMBL:M57487 xref: EMBL:M57488 xref: EMBL:M57489 xref: EMBL:M57490 xref: EMBL:M57491 xref: EMBL:M57492 xref: EMBL:M57493 xref: EMBL:M57494 xref: EMBL:S49379 xref: EMBL:U03881 xref: EMBL:U95204 xref: HGNC:HGNC:6156 xref: UniGene:Hs.218040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033141 ! ITB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007685 name: ITGB4_human def: "Integrin beta-4 precursor gene" [UniProtKB:P16144] xref: EMBL:AF011375 xref: EMBL:AF011376 xref: EMBL:AJ251004 xref: EMBL:U66530 xref: EMBL:U66531 xref: EMBL:U66532 xref: EMBL:U66533 xref: EMBL:U66534 xref: EMBL:U66535 xref: EMBL:U66536 xref: EMBL:U66537 xref: EMBL:U66538 xref: EMBL:U66539 xref: EMBL:U66540 xref: EMBL:U66541 xref: EMBL:X51841 xref: EMBL:X52186 xref: EMBL:X53587 xref: EMBL:Y11107 xref: HGNC:HGNC:6158 xref: UniGene:Hs.632226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033114 ! ITB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007686 name: ITGB5_human def: "Integrin beta-5 precursor gene" [UniProtKB:P18084] xref: EMBL:BC006541 xref: EMBL:EU332848 xref: EMBL:J05633 xref: EMBL:M35011 xref: EMBL:X53002 xref: HGNC:HGNC:6160 xref: UniGene:Hs.536663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033120 ! ITB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007687 name: ITGB6_human def: "Integrin beta-6 precursor gene" [UniProtKB:P18564] xref: EMBL:AC080166 xref: EMBL:AC092153 xref: EMBL:BC121178 xref: EMBL:M35198 xref: EMBL:S49380 xref: HGNC:HGNC:6161 xref: UniGene:Hs.470399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033133 ! ITB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007688 name: ITGB7_human def: "Integrin beta-7 precursor gene" [UniProtKB:P26010] xref: EMBL:BC015916 xref: EMBL:L23810 xref: EMBL:L23811 xref: EMBL:L23812 xref: EMBL:L23813 xref: EMBL:L23814 xref: EMBL:L23815 xref: EMBL:L23816 xref: EMBL:L23817 xref: EMBL:L23818 xref: EMBL:L23819 xref: EMBL:L23820 xref: EMBL:L23822 xref: EMBL:L23823 xref: EMBL:M62880 xref: EMBL:M68892 xref: EMBL:S49364 xref: EMBL:S49365 xref: EMBL:S49366 xref: EMBL:S49367 xref: EMBL:S49368 xref: EMBL:S49369 xref: EMBL:S49370 xref: EMBL:S49371 xref: EMBL:S49373 xref: EMBL:S49374 xref: EMBL:S49375 xref: EMBL:S49377 xref: EMBL:S49378 xref: EMBL:S80335 xref: HGNC:HGNC:6162 xref: UniGene:Hs.654470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033137 ! ITB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007689 name: ITGB8_human def: "Integrin beta-8 precursor gene" [UniProtKB:P26012] xref: EMBL:AC004130 xref: EMBL:M73780 xref: HGNC:HGNC:6163 xref: UniGene:Hs.592171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033125 ! ITB8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007691 name: KIAA0174_human def: "Uncharacterized protein KIAA0174 gene" [UniProtKB:P53990] xref: EMBL:AB097052 xref: EMBL:AK293022 xref: EMBL:BC000116 xref: EMBL:BC000430 xref: EMBL:BC004359 xref: EMBL:BC103745 xref: EMBL:D79996 xref: HGNC:HGNC:28977 xref: UniGene:Hs.232194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026635 ! K0174_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007694 name: KRT2_human def: "Keratin, type II cytoskeletal 2 epidermal gene" [UniProtKB:P35908] synonym: "KRT2A" EXACT [UniProtKB:P35908] synonym: "KRT2E" EXACT [UniProtKB:P35908] xref: EMBL:AF019084 xref: EMBL:BC096294 xref: EMBL:BC099643 xref: EMBL:BC099644 xref: EMBL:M99061 xref: HGNC:HGNC:6439 xref: UniGene:Hs.707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021657 ! K22E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007698 name: KRT4_human def: "Keratin, type II cytoskeletal 4 gene" [UniProtKB:P19013] synonym: "CYK4" EXACT [UniProtKB:P19013] xref: EMBL:AY043326 xref: EMBL:BC003630 xref: EMBL:BC042174 xref: EMBL:X07695 xref: EMBL:X61028 xref: EMBL:X67683 xref: HGNC:HGNC:6441 xref: UniGene:Hs.654610 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021644 ! K2C4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007704 name: KRT74_human def: "Keratin, type II cytoskeletal 74 gene" [UniProtKB:Q7RTS7] synonym: "K6IRS4" EXACT [UniProtKB:Q7RTS7] synonym: "KB37" EXACT [UniProtKB:Q7RTS7] synonym: "KRT5C" EXACT [UniProtKB:Q7RTS7] synonym: "KRT6IRS4" EXACT [UniProtKB:Q7RTS7] xref: EMBL:AC055715 xref: EMBL:AJ508777 xref: EMBL:BK000977 xref: EMBL:CH471054 xref: HGNC:HGNC:28929 xref: UniGene:Hs.660125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032342 ! K2C74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007709 name: PFKM_human def: "6-phosphofructokinase, muscle type gene" [UniProtKB:P08237] synonym: "PFKX" EXACT [UniProtKB:P08237] xref: EMBL:BC000534 xref: EMBL:BC012799 xref: EMBL:BC013298 xref: EMBL:BC021203 xref: EMBL:J05533 xref: EMBL:M24925 xref: EMBL:M26066 xref: EMBL:M59720 xref: EMBL:M59721 xref: EMBL:M59722 xref: EMBL:M59723 xref: EMBL:M59724 xref: EMBL:M59725 xref: EMBL:M59726 xref: EMBL:M59727 xref: EMBL:M59728 xref: EMBL:M59729 xref: EMBL:M59730 xref: EMBL:M59731 xref: EMBL:M59732 xref: EMBL:M59733 xref: EMBL:M59734 xref: EMBL:M59735 xref: EMBL:M59736 xref: EMBL:M59737 xref: EMBL:M59738 xref: EMBL:M59739 xref: EMBL:M59740 xref: EMBL:M59741 xref: EMBL:Y00698 xref: HGNC:HGNC:8877 xref: UniGene:Hs.75160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034112 ! K6PF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007710 name: PFKL_human def: "6-phosphofructokinase, liver type gene" [UniProtKB:P17858] xref: EMBL:AP001754 xref: EMBL:BC006422 xref: EMBL:BC007536 xref: EMBL:BC008964 xref: EMBL:BC009919 xref: EMBL:X15573 xref: EMBL:X16911 xref: EMBL:X16912 xref: EMBL:X16913 xref: EMBL:X16914 xref: EMBL:X16915 xref: EMBL:X16916 xref: EMBL:X16917 xref: EMBL:X16918 xref: EMBL:X16919 xref: EMBL:X16920 xref: EMBL:X16921 xref: EMBL:X16922 xref: EMBL:X16923 xref: EMBL:X16924 xref: EMBL:X16925 xref: EMBL:X16926 xref: EMBL:X16927 xref: EMBL:X16928 xref: EMBL:X16929 xref: EMBL:X16930 xref: HGNC:HGNC:8876 xref: UniGene:Hs.255093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034104 ! K6PL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007717 name: PRKAR1B_human def: "cAMP-dependent protein kinase type I-beta regulatory subunit gene" [UniProtKB:P31321] xref: EMBL:BC026734 xref: EMBL:BC036828 xref: EMBL:M65066 xref: HGNC:HGNC:9390 xref: UniGene:Hs.520851 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021337 ! KAP1_HUMAN relationship: codes_for CCO:B0021338 ! Q8N422_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007718 name: PRKAR2A_human def: "cAMP-dependent protein kinase type II-alpha regulatory subunit gene" [UniProtKB:P13861] synonym: "PKR2" EXACT [UniProtKB:P13861] synonym: "PRKAR2" EXACT [UniProtKB:P13861] xref: EMBL:BC002763 xref: EMBL:BT007225 xref: EMBL:CH471055 xref: EMBL:X14968 xref: EMBL:X99455 xref: HGNC:HGNC:9391 xref: UniGene:Hs.631923 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022455 ! KAP2_HUMAN relationship: codes_for CCO:B0022458 ! Q9BUB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007719 name: PRKAR2B_human def: "cAMP-dependent protein kinase type II-beta regulatory subunit gene" [UniProtKB:P31323] xref: EMBL:AK291441 xref: EMBL:CH236947 xref: EMBL:CH471070 xref: EMBL:EF157730 xref: EMBL:M31158 xref: HGNC:HGNC:9392 xref: UniGene:Hs.433068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022454 ! KAP3_HUMAN relationship: codes_for CCO:B0053748 ! A3R6R8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007720 name: PRKACA_human def: "cAMP-dependent protein kinase catalytic subunit alpha gene" [UniProtKB:P17612] synonym: "PKACA" EXACT [UniProtKB:P17612] xref: EMBL:AF208004 xref: EMBL:AF224718 xref: EMBL:AF239744 xref: EMBL:AK290147 xref: EMBL:BC039846 xref: EMBL:BC108259 xref: EMBL:CH471106 xref: EMBL:DQ667173 xref: EMBL:X07767 xref: HGNC:HGNC:9380 xref: UniGene:Hs.631630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018543 ! KAPCA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007721 name: PRKACB_human def: "cAMP-dependent protein kinase catalytic subunit beta gene" [UniProtKB:P22694] xref: EMBL:AB209189 xref: EMBL:AF538872 xref: EMBL:AL359504 xref: EMBL:AL450063 xref: EMBL:AY927364 xref: EMBL:AY927365 xref: EMBL:AY927366 xref: EMBL:AY927367 xref: EMBL:AY927368 xref: EMBL:BC035058 xref: EMBL:BX537705 xref: EMBL:BX641026 xref: EMBL:CH471097 xref: EMBL:CR936631 xref: EMBL:DQ667174 xref: EMBL:M34181 xref: HGNC:HGNC:9381 xref: UniGene:Hs.487325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018534 ! KAPCB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007722 name: PRKACG_human def: "cAMP-dependent protein kinase catalytic subunit gamma gene" [UniProtKB:P22612] xref: EMBL:AJ001597 xref: EMBL:AL162730 xref: EMBL:BC039888 xref: EMBL:DQ667175 xref: EMBL:M34182 xref: HGNC:HGNC:9382 xref: UniGene:Hs.158029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018532 ! KAPCG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007724 name: CSNK1D_human def: "Casein kinase I isoform delta gene" [UniProtKB:P48730] xref: EMBL:AB091044 xref: EMBL:BC003558 xref: EMBL:BC015775 xref: EMBL:U29171 xref: EMBL:U31285 xref: HGNC:HGNC:2452 xref: UniGene:Hs.631725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017481 ! KC1D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007725 name: CAMK1_human def: "Calcium/calmodulin-dependent protein kinase type 1 gene" [UniProtKB:Q14012] xref: EMBL:BC106754 xref: EMBL:BC106755 xref: EMBL:L41816 xref: HGNC:HGNC:1459 xref: UniGene:Hs.434875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016556 ! KCC1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007729 name: CAMK2A_human def: "Calcium/calmodulin-dependent protein kinase type II alpha chain gene" [UniProtKB:Q9UQM7] synonym: "CAMKA" EXACT [UniProtKB:Q9UQM7] synonym: "KIAA0968" EXACT [UniProtKB:Q9UQM7] xref: EMBL:AB023185 xref: EMBL:AF145710 xref: EMBL:AF145711 xref: HGNC:HGNC:1460 xref: UniGene:Hs.143535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016569 ! KCC2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007730 name: CAMK4_human def: "Calcium/calmodulin-dependent protein kinase type IV gene" [UniProtKB:Q16566] xref: EMBL:BC016695 xref: EMBL:BC025687 xref: EMBL:D30742 xref: EMBL:L17000 xref: EMBL:L24959 xref: HGNC:HGNC:1464 xref: UniGene:Hs.591269 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016540 ! KCC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007740 name: CKB_human def: "Creatine kinase B-type gene" [UniProtKB:P12277] synonym: "CKBB" EXACT [UniProtKB:P12277] xref: EMBL:BC001190 xref: EMBL:BC004914 xref: EMBL:BC008323 xref: EMBL:BC010002 xref: EMBL:BC019259 xref: EMBL:BC019281 xref: EMBL:DQ333313 xref: EMBL:L47647 xref: EMBL:M16364 xref: EMBL:M16451 xref: EMBL:M21237 xref: EMBL:M21238 xref: EMBL:M21239 xref: EMBL:M21240 xref: EMBL:M21241 xref: EMBL:M21242 xref: EMBL:M21243 xref: EMBL:M22355 xref: EMBL:M22356 xref: EMBL:X15334 xref: HGNC:HGNC:1991 xref: UniGene:Hs.173724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015997 ! KCRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007745 name: KHDRBS2_human def: "KH domain-containing, RNA-binding, signal transduction-associated protein 2 gene" [UniProtKB:Q5VWX1] synonym: "SLM1" EXACT [UniProtKB:Q5VWX1] xref: EMBL:AL049544 xref: EMBL:AL138882 xref: EMBL:AL355347 xref: EMBL:AL360220 xref: EMBL:AL391644 xref: EMBL:AY077838 xref: EMBL:BC034043 xref: EMBL:CH471143 xref: EMBL:Z93021 xref: HGNC:HGNC:18114 xref: UniGene:Hs.519794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016195 ! KHDR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007746 name: KIF18A_human def: "Kinesin-like protein KIF18A gene" [UniProtKB:Q8NI77] synonym: "OK/SW-cl.108" EXACT [UniProtKB:Q8NI77] xref: EMBL:AB062483 xref: EMBL:AL136819 xref: EMBL:AY791349 xref: EMBL:BC048347 xref: HGNC:HGNC:29441 xref: UniGene:Hs.301052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026171 ! KI18A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007754 name: PRKCE_human def: "Protein kinase C epsilon type gene" [UniProtKB:Q02156] synonym: "PKCE" EXACT [UniProtKB:Q02156] xref: EMBL:AC017006 xref: EMBL:AC017078 xref: EMBL:BC109033 xref: EMBL:BC109034 xref: EMBL:U51244 xref: EMBL:X65293 xref: HGNC:HGNC:9401 xref: UniGene:Hs.580351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025054 ! KPCE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007755 name: PRKCG_human def: "Protein kinase C gamma type gene" [UniProtKB:P05129] synonym: "PKCG" EXACT [UniProtKB:P05129] xref: EMBL:AF345987 xref: EMBL:BC047876 xref: EMBL:M13977 xref: EMBL:Z15114 xref: HGNC:HGNC:9402 xref: UniGene:Hs.631564 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025044 ! KPCG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007756 name: PRKCH_human def: "Protein kinase C eta type gene" [UniProtKB:P24723] synonym: "PKCL" EXACT [UniProtKB:P24723] synonym: "PRKCL" EXACT [UniProtKB:P24723] xref: EMBL:AK290183 xref: EMBL:BC037268 xref: EMBL:CH471061 xref: EMBL:M55284 xref: EMBL:S74620 xref: HGNC:HGNC:9403 xref: UniGene:Hs.333907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025046 ! KPCL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007757 name: PRKCQ_human def: "Protein kinase C theta type gene" [UniProtKB:Q04759] synonym: "PRKCT" EXACT [UniProtKB:Q04759] xref: EMBL:AL137145 xref: EMBL:AL158043 xref: EMBL:AY702977 xref: EMBL:BC101465 xref: EMBL:BC113359 xref: EMBL:L01087 xref: EMBL:L07032 xref: HGNC:HGNC:9410 xref: UniGene:Hs.498570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025051 ! Q5JUN8_HUMAN relationship: codes_for CCO:B0025053 ! KPCT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007769 name: L1CAM_human def: "Neural cell adhesion molecule L1 precursor gene" [UniProtKB:P32004] synonym: "CAML1" EXACT [UniProtKB:P32004] synonym: "MIC5" EXACT [UniProtKB:P32004] xref: EMBL:BC025843 xref: EMBL:BC126229 xref: EMBL:M55271 xref: EMBL:M74387 xref: EMBL:M77640 xref: EMBL:U52111 xref: EMBL:U52112 xref: EMBL:X58775 xref: EMBL:X58776 xref: EMBL:X59847 xref: EMBL:Z29373 xref: HGNC:HGNC:6470 xref: UniGene:Hs.522818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029795 ! L1CAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007771 name: LANCL1_human def: "LanC-like protein 1 gene" [UniProtKB:O43813] synonym: "GPR69A" EXACT [UniProtKB:O43813] xref: EMBL:AJ289236 xref: EMBL:AJ289237 xref: EMBL:AJ289238 xref: EMBL:AJ289239 xref: EMBL:BC028685 xref: EMBL:Y11395 xref: HGNC:HGNC:6508 xref: UniGene:Hs.13351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026166 ! LANC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007772 name: LANCL2_human def: "LanC-like protein 2 gene" [UniProtKB:Q9NS86] synonym: "GPR69B" EXACT [UniProtKB:Q9NS86] synonym: "TASP" EXACT [UniProtKB:Q9NS86] xref: EMBL:AB035966 xref: EMBL:AC073347 xref: EMBL:AF353942 xref: EMBL:AJ278245 xref: EMBL:AL713665 xref: EMBL:BC004887 xref: HGNC:HGNC:6509 xref: UniGene:Hs.655117 xref: UniGene:Hs.696108 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026163 ! LANC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007773 name: LASS2_human def: "LAG1 longevity assurance homolog 2 gene" [UniProtKB:Q96G23] synonym: "TMSG1" EXACT [UniProtKB:Q96G23] xref: EMBL:AF177338 xref: EMBL:AF189062 xref: EMBL:AK001105 xref: EMBL:AL590133 xref: EMBL:AY091458 xref: EMBL:BC001357 xref: EMBL:BC010032 xref: HGNC:HGNC:14076 xref: UniGene:Hs.702049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033374 ! Q5SZE3_HUMAN relationship: codes_for CCO:B0033375 ! LASS2_HUMAN relationship: codes_for CCO:B0033376 ! Q5SZE4_HUMAN relationship: codes_for CCO:B0033381 ! Q5SZE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007774 name: LASS3_human def: "LAG1 longevity assurance homolog 3 gene" [UniProtKB:Q8IU89] xref: EMBL:BC028703 xref: EMBL:BC034500 xref: EMBL:BC034970 xref: HGNC:HGNC:23752 xref: UniGene:Hs.662371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033366 ! LASS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007775 name: LASS4_human def: "LAG1 longevity assurance homolog 4 gene" [UniProtKB:Q9HA82] xref: EMBL:AK022151 xref: EMBL:BC009828 xref: HGNC:HGNC:23747 xref: UniGene:Hs.515111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033365 ! LASS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007776 name: LASS5_human def: "LAG1 longevity assurance homolog 5 gene" [UniProtKB:Q8N5B7] xref: EMBL:BC032565 xref: EMBL:BC033558 xref: HGNC:HGNC:23749 xref: UniGene:Hs.270525 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033378 ! LASS5_HUMAN relationship: codes_for CCO:B0033384 ! Q49AQ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007777 name: LASS6_human def: "LAG1 longevity assurance homolog 6 gene" [UniProtKB:Q6ZMG9] xref: EMBL:AK172775 xref: EMBL:BC030800 xref: EMBL:BC109284 xref: EMBL:BC109285 xref: HGNC:HGNC:23826 xref: UniGene:Hs.506829 xref: UniGene:Hs.705995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033369 ! LASS6_HUMAN relationship: codes_for CCO:B0033382 ! Q32M63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007779 name: LIMD1_human def: "LIM domain-containing protein 1 gene" [UniProtKB:Q9UGP4] xref: EMBL:AJ132408 xref: EMBL:AJ297357 xref: EMBL:AJ312686 xref: EMBL:BC117236 xref: EMBL:BC117238 xref: HGNC:HGNC:6612 xref: UniGene:Hs.193370 xref: UniGene:Hs.621057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031064 ! LIMD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007780 name: PPFIA1_human def: "Liprin-alpha-1 gene" [UniProtKB:Q13136] synonym: "LIP1" EXACT [UniProtKB:Q13136] xref: EMBL:AP002336 xref: EMBL:BC034046 xref: EMBL:D49354 xref: EMBL:U22815 xref: EMBL:U22816 xref: HGNC:HGNC:9245 xref: UniGene:Hs.530749 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031630 ! LIPA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007783 name: LTA4H_human def: "Leukotriene A-4 hydrolase gene" [UniProtKB:P09960] synonym: "LTA4" EXACT [UniProtKB:P09960] xref: EMBL:BC032528 xref: EMBL:J02959 xref: EMBL:J03459 xref: EMBL:U27275 xref: EMBL:U27276 xref: EMBL:U27277 xref: EMBL:U27278 xref: EMBL:U27279 xref: EMBL:U27280 xref: EMBL:U27281 xref: EMBL:U27282 xref: EMBL:U27283 xref: EMBL:U27284 xref: EMBL:U27285 xref: EMBL:U27286 xref: EMBL:U27287 xref: EMBL:U27288 xref: EMBL:U27289 xref: EMBL:U27290 xref: EMBL:U27291 xref: EMBL:U27292 xref: EMBL:U27293 xref: EMBL:U43410 xref: EMBL:U43411 xref: HGNC:HGNC:6710 xref: UniGene:Hs.524648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024129 ! LKHA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007791 name: LPXN_human def: "Leupaxin gene" [UniProtKB:O60711] synonym: "LDLP" EXACT [UniProtKB:O60711] xref: EMBL:AF062075 xref: EMBL:BC019035 xref: HGNC:HGNC:14061 xref: UniGene:Hs.125474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017845 ! LPXN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007794 name: LRP1_human def: "Prolow-density lipoprotein receptor-related protein 1 precursor gene" [UniProtKB:Q07954] synonym: "A2MR" EXACT [UniProtKB:Q07954] synonym: "APR" EXACT [UniProtKB:Q07954] xref: EMBL:AC023237 xref: EMBL:AC137628 xref: EMBL:AC137834 xref: EMBL:AF058427 xref: EMBL:DQ314873 xref: EMBL:X13916 xref: EMBL:X15424 xref: EMBL:Y18524 xref: HGNC:HGNC:6692 xref: UniGene:Hs.162757 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025953 ! LRP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007797 name: LRP5_human def: "Low-density lipoprotein receptor-related protein 5 precursor gene" [UniProtKB:O75197] synonym: "LRP7" EXACT [UniProtKB:O75197] xref: EMBL:AB017498 xref: EMBL:AF064548 xref: EMBL:AF283320 xref: EMBL:AF283321 xref: HGNC:HGNC:6697 xref: UniGene:Hs.6347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025951 ! LRP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007798 name: LRP6_human def: "Low-density lipoprotein receptor-related protein 6 precursor gene" [UniProtKB:O75581] xref: EMBL:AF074264 xref: EMBL:BC117136 xref: EMBL:BC126405 xref: HGNC:HGNC:6698 xref: UniGene:Hs.584775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025967 ! LRP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007799 name: LRP8_human def: "Low-density lipoprotein receptor-related protein 8 precursor gene" [UniProtKB:Q14114] synonym: "APOER2" EXACT [UniProtKB:Q14114] xref: EMBL:AL355483 xref: EMBL:AL606760 xref: EMBL:BC006443 xref: EMBL:BC051836 xref: EMBL:D50678 xref: EMBL:D86407 xref: EMBL:Z75190 xref: HGNC:HGNC:6700 xref: UniGene:Hs.576154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033477 ! LRP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007801 name: LRRFIP1_human def: "Leucine-rich repeat flightless-interacting protein 1 gene" [UniProtKB:Q32MZ4] synonym: "GCF2" EXACT [UniProtKB:Q32MZ4] synonym: "TRIP" EXACT [UniProtKB:Q32MZ4] xref: EMBL:AC012076 xref: EMBL:AJ223075 xref: EMBL:BC001385 xref: EMBL:BC108913 xref: EMBL:BC108914 xref: EMBL:U69609 xref: HGNC:HGNC:6702 xref: UniGene:Hs.471779 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032520 ! LRRF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007802 name: LRRFIP2_human def: "Leucine-rich repeat flightless-interacting protein 2 gene" [UniProtKB:Q9Y608] xref: EMBL:AF115509 xref: EMBL:AK000255 xref: EMBL:BC053668 xref: EMBL:CR749705 xref: HGNC:HGNC:6703 xref: UniGene:Hs.475319 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032521 ! LRRF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007806 name: MAP3K10_human def: "Mitogen-activated protein kinase kinase kinase 10 gene" [UniProtKB:Q02779] synonym: "MLK2" EXACT [UniProtKB:Q02779] synonym: "MST" EXACT [UniProtKB:Q02779] xref: EMBL:X90846 xref: EMBL:Z48615 xref: HGNC:HGNC:6849 xref: UniGene:Hs.466743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018770 ! M3K10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007807 name: MAP3K12_human def: "Mitogen-activated protein kinase kinase kinase 12 gene" [UniProtKB:Q12852] synonym: "ZPK" EXACT [UniProtKB:Q12852] xref: EMBL:AF283475 xref: EMBL:BC050050 xref: EMBL:U07358 xref: HGNC:HGNC:6851 xref: UniGene:Hs.701990 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018778 ! M3K12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007808 name: MAP3K13_human def: "Mitogen-activated protein kinase kinase kinase 13 gene" [UniProtKB:O43283] synonym: "LZK" EXACT [UniProtKB:O43283] xref: EMBL:AB001872 xref: EMBL:BC031677 xref: EMBL:BC111726 xref: EMBL:Z25428 xref: HGNC:HGNC:6852 xref: UniGene:Hs.656069 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018761 ! M3K13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007809 name: MLK4_human def: "Mitogen-activated protein kinase kinase kinase gene" [UniProtKB:Q5TCX8] synonym: "KIAA1804" EXACT [UniProtKB:Q5TCX8] xref: EMBL:AB058707 xref: EMBL:AJ311797 xref: EMBL:AJ311798 xref: EMBL:AL133380 xref: UniGene:Hs.547779 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018759 ! M3KL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007811 name: MAFB_human def: "Transcription factor MafB gene" [UniProtKB:Q9Y5Q3] synonym: "KRML" EXACT [UniProtKB:Q9Y5Q3] xref: EMBL:AF134157 xref: EMBL:AL035665 xref: EMBL:BC028098 xref: EMBL:BC036689 xref: HGNC:HGNC:6408 xref: UniGene:Hs.702085 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033733 ! MAFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007812 name: MAF_human def: "Transcription factor Maf gene" [UniProtKB:O75444] xref: EMBL:AF055376 xref: EMBL:AF055377 xref: EMBL:AF055378 xref: HGNC:HGNC:6776 xref: UniGene:Hs.134859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033734 ! MAF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007816 name: MBP_human def: "Myelin basic protein gene" [UniProtKB:P02686] xref: EMBL:AB208986 xref: EMBL:AC093330 xref: EMBL:BC008749 xref: EMBL:BC065248 xref: EMBL:BC080654 xref: EMBL:BC101771 xref: EMBL:BC101773 xref: EMBL:CR536534 xref: EMBL:CR541919 xref: EMBL:CR627018 xref: EMBL:L18862 xref: EMBL:L18864 xref: EMBL:L18865 xref: EMBL:L18866 xref: EMBL:L41657 xref: EMBL:M13577 xref: EMBL:M20009 xref: EMBL:M30047 xref: EMBL:M30515 xref: EMBL:M30516 xref: EMBL:M63599 xref: EMBL:X17286 xref: EMBL:X17287 xref: EMBL:X17288 xref: EMBL:X17289 xref: EMBL:X17290 xref: EMBL:X17369 xref: HGNC:HGNC:6925 xref: UniGene:Hs.551713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031679 ! MBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007817 name: SCYE1_human def: "Multisynthetase complex auxiliary component p43 gene" [UniProtKB:Q12904] synonym: "EMAP2" EXACT [UniProtKB:Q12904] xref: EMBL:BC014051 xref: EMBL:CR542281 xref: EMBL:U10117 xref: HGNC:HGNC:10648 xref: UniGene:Hs.591680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027467 ! MCA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007818 name: MDH2_human def: "Malate dehydrogenase, mitochondrial precursor gene" [UniProtKB:P40926] xref: EMBL:AF047470 xref: EMBL:AK290779 xref: EMBL:BC001917 xref: EMBL:CH471220 xref: HGNC:HGNC:6971 xref: UniGene:Hs.520967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030700 ! MDHM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007819 name: MEIS1_human def: "Homeobox protein Meis1 gene" [UniProtKB:O00470] xref: EMBL:AC007392 xref: EMBL:AC092669 xref: EMBL:AC093641 xref: EMBL:BC036511 xref: EMBL:BC043503 xref: EMBL:CH471053 xref: EMBL:CR612956 xref: EMBL:U85707 xref: HGNC:HGNC:7000 xref: UniGene:Hs.526754 xref: UniGene:Hs.603755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032489 ! MEIS1_HUMAN relationship: codes_for CCO:B0032495 ! Q4G0U8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007820 name: MEIS2_human def: "Homeobox protein Meis2 gene" [UniProtKB:O14770] synonym: "MRG1" EXACT [UniProtKB:O14770] xref: EMBL:AC018563 xref: EMBL:AF017418 xref: EMBL:AF178948 xref: EMBL:AF179896 xref: EMBL:AF179897 xref: EMBL:AF179898 xref: EMBL:AF179899 xref: EMBL:BC001516 xref: EMBL:BC001844 xref: EMBL:BC007202 xref: EMBL:BC050431 xref: EMBL:CH471125 xref: HGNC:HGNC:7001 xref: UniGene:Hs.510989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032498 ! A8MWD5_HUMAN relationship: codes_for CCO:B0032499 ! MEIS2_HUMAN relationship: codes_for CCO:B0032508 ! Q96DI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007821 name: MEIS3_human def: "Homeobox protein Meis3 gene" [UniProtKB:Q99687] synonym: "MRG2" EXACT [UniProtKB:Q99687] xref: EMBL:AL359938 xref: EMBL:BC025404 xref: EMBL:BC069251 xref: EMBL:CR749687 xref: EMBL:U68385 xref: HGNC:HGNC:29537 xref: UniGene:Hs.380923 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032501 ! MEIS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007823 name: MAPK9_human def: "Mitogen-activated protein kinase 9 gene" [UniProtKB:P45984] synonym: "JNK2" EXACT [UniProtKB:P45984] synonym: "PRKM9" EXACT [UniProtKB:P45984] xref: EMBL:BC032539 xref: EMBL:CR536580 xref: EMBL:DQ066599 xref: EMBL:L31951 xref: EMBL:U09759 xref: EMBL:U34821 xref: EMBL:U35002 xref: EMBL:U35003 xref: HGNC:HGNC:6886 xref: UniGene:Hs.654461 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026769 ! MK09_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007824 name: MAPK10_human def: "Mitogen-activated protein kinase 10 gene" [UniProtKB:P53779] synonym: "JNK3" EXACT [UniProtKB:P53779] synonym: "JNK3A" EXACT [UniProtKB:P53779] synonym: "PRKM10" EXACT [UniProtKB:P53779] xref: EMBL:AC096953 xref: EMBL:BC035057 xref: EMBL:CH471057 xref: EMBL:U07620 xref: EMBL:U34819 xref: EMBL:U34820 xref: HGNC:HGNC:6872 xref: UniGene:Hs.125503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026768 ! MK10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007825 name: MAPK14_human def: "Mitogen-activated protein kinase 14 gene" [UniProtKB:Q16539] synonym: "CSBP" EXACT [UniProtKB:Q16539] synonym: "CSBP1" EXACT [UniProtKB:Q16539] synonym: "CSBP2" EXACT [UniProtKB:Q16539] synonym: "CSPB1" EXACT [UniProtKB:Q16539] synonym: "MXI2" EXACT [UniProtKB:Q16539] xref: EMBL:AB074150 xref: EMBL:AF100544 xref: EMBL:AK291709 xref: EMBL:BC000092 xref: EMBL:BC031574 xref: EMBL:BT006933 xref: EMBL:CH471081 xref: EMBL:CR536505 xref: EMBL:EU332860 xref: EMBL:L35253 xref: EMBL:L35263 xref: EMBL:L35264 xref: EMBL:U19775 xref: EMBL:Z95152 xref: HGNC:HGNC:6876 xref: UniGene:Hs.485233 xref: UniGene:Hs.588289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021108 ! MK14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007826 name: MKLN1_human def: "Muskelin gene" [UniProtKB:Q9UL63] xref: EMBL:AC018642 xref: EMBL:AF047489 xref: EMBL:AK002024 xref: EMBL:AL162071 xref: EMBL:BC002834 xref: EMBL:BC067825 xref: EMBL:CH236950 xref: EMBL:CH471070 xref: HGNC:HGNC:7109 xref: UniGene:Hs.702060 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029277 ! MKLN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007828 name: MND1_human def: "Meiotic nuclear division protein 1 homolog gene" [UniProtKB:Q9BWT6] synonym: "GAJ" EXACT [UniProtKB:Q9BWT6] xref: EMBL:AY028916 xref: EMBL:BC032142 xref: EMBL:CH471056 xref: HGNC:HGNC:24839 xref: UniGene:Hs.294088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032873 ! MND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007829 name: MSN_human def: "Moesin gene" [UniProtKB:P26038] xref: EMBL:BC017293 xref: EMBL:M69066 xref: EMBL:Z98946 xref: HGNC:HGNC:7373 xref: UniGene:Hs.87752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018220 ! MOES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007831 name: MOBKL1B_human def: "Mps one binder kinase activator-like 1B gene" [UniProtKB:Q9H8S9] synonym: "C2orf6" EXACT [UniProtKB:Q9H8S9] synonym: "MOB4B" EXACT [UniProtKB:Q9H8S9] synonym: "MOBK1B" EXACT [UniProtKB:Q9H8S9] xref: EMBL:AB016839 xref: EMBL:AC073263 xref: EMBL:AJ577474 xref: EMBL:AK001650 xref: EMBL:AK021657 xref: EMBL:AK023321 xref: EMBL:BC003398 xref: HGNC:HGNC:16015 xref: UniGene:Hs.196437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024568 ! MOL1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007832 name: MAP2K2_human def: "Dual specificity mitogen-activated protein kinase kinase 2 gene" [UniProtKB:P36507] synonym: "MEK2" EXACT [UniProtKB:P36507] synonym: "MKK2" EXACT [UniProtKB:P36507] synonym: "PRKMK2" EXACT [UniProtKB:P36507] xref: EMBL:BC000471 xref: EMBL:BC018645 xref: EMBL:L11285 xref: HGNC:HGNC:6842 xref: UniGene:Hs.465627 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017421 ! MP2K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007836 name: MRGPRF_human def: "Mas-related G-protein coupled receptor member F gene" [UniProtKB:Q96AM1] synonym: "GPR140" EXACT [UniProtKB:Q96AM1] synonym: "GPR168" EXACT [UniProtKB:Q96AM1] synonym: "MRGF" EXACT [UniProtKB:Q96AM1] synonym: "PSEC0142" EXACT [UniProtKB:Q96AM1] xref: EMBL:AK075450 xref: EMBL:BC016964 xref: HGNC:HGNC:24828 xref: UniGene:Hs.118513 xref: UniGene:Hs.602397 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026726 ! MRGRF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007838 name: MS4A7_human def: "Membrane-spanning 4-domains subfamily A member 7 gene" [UniProtKB:Q9GZW8] synonym: "4SPAN2" EXACT [UniProtKB:Q9GZW8] synonym: "CD20L4" EXACT [UniProtKB:Q9GZW8] synonym: "CFFM4" EXACT [UniProtKB:Q9GZW8] xref: EMBL:AB026043 xref: EMBL:AF201951 xref: EMBL:AF237916 xref: EMBL:AF309653 xref: EMBL:AF350501 xref: EMBL:AK075106 xref: EMBL:AK297027 xref: EMBL:AP003127 xref: EMBL:BC020673 xref: EMBL:CH471076 xref: HGNC:HGNC:13378 xref: UniGene:Hs.530735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025401 ! MS4A7_HUMAN relationship: codes_for CCO:B0025403 ! A6NP53_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007839 name: MST4_human def: "Serine/threonine-protein kinase MST4 gene" [UniProtKB:Q9P289] synonym: "MASK" EXACT [UniProtKB:Q9P289] xref: EMBL:AB040057 xref: EMBL:AF231012 xref: EMBL:AF344882 xref: EMBL:AL109749 xref: EMBL:BC098315 xref: EMBL:BC103503 xref: EMBL:BT020099 xref: UniGene:Hs.444247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022753 ! MST4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007843 name: ADI1_human def: "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase gene" [UniProtKB:Q9BV57] synonym: "HMFT1638" EXACT [UniProtKB:Q9BV57] synonym: "MTCBP1" EXACT [UniProtKB:Q9BV57] xref: EMBL:AB073609 xref: EMBL:AB158319 xref: EMBL:AC114810 xref: EMBL:AC142528 xref: EMBL:AF087863 xref: EMBL:AF403478 xref: EMBL:AK001775 xref: EMBL:AK127473 xref: EMBL:AK222467 xref: EMBL:BC001467 xref: HGNC:HGNC:30576 xref: UniGene:Hs.502773 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032391 ! MTND_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007848 name: MYH1_human def: "Myosin-1 gene" [UniProtKB:P12882] xref: EMBL:AF111785 xref: EMBL:BC114545 xref: EMBL:X03740 xref: HGNC:HGNC:7567 xref: UniGene:Hs.440895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027842 ! MYH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007855 name: MYH9_human def: "Myosin-9 gene" [UniProtKB:P35579] xref: EMBL:AL832639 xref: EMBL:CR456526 xref: EMBL:M31013 xref: EMBL:M69180 xref: EMBL:M81105 xref: EMBL:Z82215 xref: HGNC:HGNC:7579 xref: UniGene:Hs.474751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019193 ! MYH9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007858 name: MYST3_human def: "Histone acetyltransferase MYST3 gene" [UniProtKB:Q92794] synonym: "MOZ" EXACT [UniProtKB:Q92794] synonym: "RUNXBP2" EXACT [UniProtKB:Q92794] synonym: "ZNF220" EXACT [UniProtKB:Q92794] xref: EMBL:AB084281 xref: EMBL:AC090571 xref: EMBL:U47742 xref: HGNC:HGNC:13013 xref: UniGene:Hs.491577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017927 ! MYST3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007859 name: MYST4_human def: "Histone acetyltransferase MYST4 gene" [UniProtKB:Q8WYB5] synonym: "KIAA0383" EXACT [UniProtKB:Q8WYB5] synonym: "MORF" EXACT [UniProtKB:Q8WYB5] synonym: "MOZ2" EXACT [UniProtKB:Q8WYB5] xref: EMBL:AB002381 xref: EMBL:AF113514 xref: EMBL:AF119230 xref: EMBL:AF119231 xref: EMBL:AF217500 xref: EMBL:BC014143 xref: EMBL:BC021128 xref: EMBL:BC048199 xref: HGNC:HGNC:17582 xref: UniGene:Hs.35758 xref: UniGene:Hs.599543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017931 ! MYST4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007862 name: ULBP3_human def: "NKG2D ligand 3 precursor gene" [UniProtKB:Q9BZM4] synonym: "N2DL3" EXACT [UniProtKB:Q9BZM4] synonym: "RAET1N" EXACT [UniProtKB:Q9BZM4] xref: EMBL:AB052908 xref: EMBL:AF304379 xref: EMBL:AF346596 xref: EMBL:AY027538 xref: HGNC:HGNC:14895 xref: UniGene:Hs.326556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020491 ! N2DL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007863 name: NUP62CL_human def: "Nucleoporin-62 C-terminal-like protein gene" [UniProtKB:Q9H1M0] synonym: "NUP62L" EXACT [UniProtKB:Q9H1M0] xref: EMBL:AK000137 xref: EMBL:AL390039 xref: EMBL:BC016327 xref: EMBL:BC017799 xref: HGNC:HGNC:25960 xref: UniGene:Hs.163629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021714 ! N62CL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007864 name: NARFL_human def: "Nuclear prelamin A recognition factor-like protein gene" [UniProtKB:Q9H6Q4] synonym: "PRN" EXACT [UniProtKB:Q9H6Q4] xref: EMBL:AE006464 xref: EMBL:AK025641 xref: EMBL:AK025861 xref: EMBL:AK223005 xref: EMBL:AY129231 xref: EMBL:BC030248 xref: EMBL:BC129940 xref: EMBL:Z98258 xref: HGNC:HGNC:14179 xref: UniGene:Hs.513247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031899 ! NARFL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007869 name: NEDD4L_human def: "E3 ubiquitin-protein ligase NEDD4-like protein gene" [UniProtKB:Q96PU5] synonym: "KIAA0439" EXACT [UniProtKB:Q96PU5] synonym: "NEDL3" EXACT [UniProtKB:Q96PU5] xref: EMBL:AB007899 xref: EMBL:AB071179 xref: EMBL:AF210730 xref: EMBL:AF385931 xref: EMBL:AL137469 xref: EMBL:AY112983 xref: EMBL:AY112984 xref: EMBL:AY112985 xref: EMBL:AY312514 xref: EMBL:BC000621 xref: EMBL:BC019345 xref: EMBL:BC032597 xref: HGNC:HGNC:7728 xref: UniGene:Hs.185677 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034087 ! NED4L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007871 name: NEK3_human def: "Serine/threonine-protein kinase Nek3 gene" [UniProtKB:P51956] xref: EMBL:AB072828 xref: EMBL:AK290259 xref: EMBL:AL139082 xref: EMBL:BC019916 xref: EMBL:CH471075 xref: EMBL:Z25434 xref: EMBL:Z29067 xref: HGNC:HGNC:7746 xref: UniGene:Hs.409989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028319 ! NEK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007875 name: NFE2L1_human def: "Nuclear factor erythroid 2-related factor 1 gene" [UniProtKB:Q14494] synonym: "HBZ17" EXACT [UniProtKB:Q14494] synonym: "NRF1" EXACT [UniProtKB:Q14494] synonym: "TCF11" EXACT [UniProtKB:Q14494] xref: EMBL:BC010623 xref: EMBL:L24123 xref: EMBL:U08853 xref: EMBL:X77366 xref: HGNC:HGNC:7781 xref: UniGene:Hs.514284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032380 ! NF2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007878 name: RASAL2_human def: "Ras GTPase-activating protein nGAP gene" [UniProtKB:Q9UJF2] synonym: "NGAP" EXACT [UniProtKB:Q9UJF2] xref: EMBL:AF047711 xref: EMBL:AL035702 xref: EMBL:AL160281 xref: EMBL:AL365357 xref: EMBL:AL499617 xref: HGNC:HGNC:9874 xref: UniGene:Hs.656823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019350 ! NGAP_HUMAN relationship: codes_for CCO:B0051401 ! B1AKC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007879 name: NEUROG2_human def: "Neurogenin-2 gene" [UniProtKB:Q9H2A3] synonym: "ATOH4" EXACT [UniProtKB:Q9H2A3] synonym: "NGN2" EXACT [UniProtKB:Q9H2A3] xref: EMBL:AF303002 xref: EMBL:BC036847 xref: HGNC:HGNC:13805 xref: UniGene:Hs.567563 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030506 ! NGN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007880 name: NEUROG3_human def: "Neurogenin-3 gene" [UniProtKB:Q9Y4Z2] synonym: "ATOH5" EXACT [UniProtKB:Q9Y4Z2] synonym: "NGN3" EXACT [UniProtKB:Q9Y4Z2] xref: EMBL:AF234829 xref: EMBL:AJ133776 xref: EMBL:AK313952 xref: EMBL:AL450311 xref: EMBL:BC117488 xref: EMBL:BC126468 xref: EMBL:CH471083 xref: HGNC:HGNC:13806 xref: UniGene:Hs.532682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030504 ! Q5VVI0_HUMAN relationship: codes_for CCO:B0030509 ! NGN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007881 name: GRIN2A_human def: "Glutamate [NMDA] receptor subunit epsilon-1 precursor gene" [UniProtKB:Q12879] synonym: "NMDAR2A" EXACT [UniProtKB:Q12879] xref: EMBL:U09002 xref: EMBL:U90277 xref: HGNC:HGNC:4585 xref: UniGene:Hs.567280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033427 ! NMDE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007882 name: GRIN2B_human def: "Glutamate [NMDA] receptor subunit epsilon-2 precursor gene" [UniProtKB:Q13224] synonym: "NMDAR2B" EXACT [UniProtKB:Q13224] xref: EMBL:BC113618 xref: EMBL:BC113620 xref: EMBL:U11287 xref: EMBL:U28758 xref: EMBL:U28861 xref: EMBL:U28862 xref: EMBL:U88963 xref: EMBL:U90278 xref: HGNC:HGNC:4586 xref: UniGene:Hs.654430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033431 ! NMDE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007884 name: GRIN2D_human def: "Glutamate [NMDA] receptor subunit epsilon-4 precursor gene" [UniProtKB:O15399] synonym: "NMDAR2D" EXACT [UniProtKB:O15399] xref: EMBL:U77783 xref: HGNC:HGNC:4588 xref: UniGene:Hs.445015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033433 ! NMDE4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007889 name: OLFM2_human def: "Noelin-2 precursor gene" [UniProtKB:O95897] synonym: "NOE2" EXACT [UniProtKB:O95897] xref: EMBL:AC008742 xref: EMBL:AF131839 xref: EMBL:BC011361 xref: EMBL:BK001428 xref: HGNC:HGNC:17189 xref: UniGene:Hs.169743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031787 ! NOE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007891 name: NOTCH3_human def: "Neurogenic locus notch homolog protein 3 precursor gene" [UniProtKB:Q9UM47] xref: EMBL:AC004257 xref: EMBL:AC004663 xref: EMBL:AF058881 xref: EMBL:AF058882 xref: EMBL:AF058883 xref: EMBL:AF058884 xref: EMBL:AF058885 xref: EMBL:AF058886 xref: EMBL:AF058887 xref: EMBL:AF058888 xref: EMBL:AF058889 xref: EMBL:AF058890 xref: EMBL:AF058891 xref: EMBL:AF058892 xref: EMBL:AF058893 xref: EMBL:AF058894 xref: EMBL:AF058895 xref: EMBL:AF058896 xref: EMBL:AF058897 xref: EMBL:AF058898 xref: EMBL:AF058899 xref: EMBL:AF058900 xref: EMBL:U97669 xref: HGNC:HGNC:7883 xref: UniGene:Hs.8546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017820 ! NOTC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007893 name: NPAS2_human def: "Neuronal PAS domain-containing protein 2 gene" [UniProtKB:Q99743] synonym: "MOP4" EXACT [UniProtKB:Q99743] xref: EMBL:BC051351 xref: EMBL:BC072383 xref: EMBL:U51625 xref: EMBL:U77970 xref: HGNC:HGNC:7895 xref: UniGene:Hs.156832 xref: UniGene:Hs.705895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026530 ! NPAS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007896 name: NR2F6_human def: "Nuclear receptor subfamily 2 group F member 6 gene" [UniProtKB:P10588] synonym: "EAR2" EXACT [UniProtKB:P10588] synonym: "ERBAL2" EXACT [UniProtKB:P10588] xref: EMBL:BC002669 xref: EMBL:BC063018 xref: EMBL:BC084544 xref: EMBL:X12794 xref: HGNC:HGNC:7977 xref: UniGene:Hs.466148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024893 ! NR2F6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007897 name: NR6A1_human def: "Nuclear receptor subfamily 6 group A member 1 gene" [UniProtKB:Q15406] synonym: "GCNF" EXACT [UniProtKB:Q15406] xref: EMBL:AF004291 xref: EMBL:AL158075 xref: EMBL:AL354928 xref: EMBL:AL354979 xref: EMBL:BC030600 xref: EMBL:S83309 xref: EMBL:U64876 xref: EMBL:U80802 xref: EMBL:X99975 xref: HGNC:HGNC:7985 xref: UniGene:Hs.586460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024873 ! NR6A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007898 name: NRCAM_human def: "Neuronal cell adhesion molecule precursor gene" [UniProtKB:Q92823] synonym: "KIAA0343" EXACT [UniProtKB:Q92823] xref: EMBL:AB002341 xref: EMBL:AC005683 xref: EMBL:AC007567 xref: EMBL:AF172277 xref: EMBL:AJ001054 xref: EMBL:AJ001057 xref: EMBL:BX538010 xref: EMBL:CH236947 xref: EMBL:CH471070 xref: EMBL:U55258 xref: HGNC:HGNC:7994 xref: UniGene:Hs.21422 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015672 ! NRCAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007901 name: SCYL1_human def: "N-terminal kinase-like protein gene" [UniProtKB:Q96KG9] synonym: "GKLP" EXACT [UniProtKB:Q96KG9] synonym: "HT019" EXACT [UniProtKB:Q96KG9] synonym: "NTKL" EXACT [UniProtKB:Q96KG9] synonym: "TAPK" EXACT [UniProtKB:Q96KG9] synonym: "TEIF" EXACT [UniProtKB:Q96KG9] synonym: "TRAP" EXACT [UniProtKB:Q96KG9] xref: EMBL:AB047077 xref: EMBL:AB051427 xref: EMBL:AB051428 xref: EMBL:AF225424 xref: EMBL:AF255613 xref: EMBL:AF297709 xref: EMBL:AP000769 xref: EMBL:BC009967 xref: EMBL:BC069233 xref: EMBL:CH471076 xref: HGNC:HGNC:14372 xref: UniGene:Hs.238839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031563 ! NTKL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007904 name: NUDT3_human def: "Diphosphoinositol polyphosphate phosphohydrolase 1 gene" [UniProtKB:O95989] synonym: "DIPP" EXACT [UniProtKB:O95989] synonym: "DIPP1" EXACT [UniProtKB:O95989] xref: EMBL:AF062529 xref: EMBL:AF062530 xref: EMBL:AL355855 xref: EMBL:BC007727 xref: EMBL:BT019984 xref: EMBL:BT019985 xref: EMBL:Z98036 xref: HGNC:HGNC:8050 xref: UniGene:Hs.188882 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026419 ! NUDT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007905 name: NUDT4_human def: "Diphosphoinositol polyphosphate phosphohydrolase 2 gene" [UniProtKB:Q9NZJ9] synonym: "DIPP2" EXACT [UniProtKB:Q9NZJ9] synonym: "HDCMB47P" EXACT [UniProtKB:Q9NZJ9] synonym: "KIAA0487" EXACT [UniProtKB:Q9NZJ9] xref: EMBL:AB007956 xref: EMBL:AF067803 xref: EMBL:AF191649 xref: EMBL:AF191650 xref: EMBL:AF191651 xref: EMBL:AF191652 xref: EMBL:AF191653 xref: EMBL:AK223497 xref: EMBL:BC012069 xref: EMBL:BC051310 xref: EMBL:BT020109 xref: EMBL:BT020110 xref: EMBL:CR749445 xref: HGNC:HGNC:8051 xref: UniGene:Hs.591008 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026418 ! NUDT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007907 name: NUP62_human def: "Nuclear pore glycoprotein p62 gene" [UniProtKB:P37198] xref: EMBL:AL162061 xref: EMBL:BC003663 xref: EMBL:BC014842 xref: EMBL:BC050717 xref: EMBL:BC095410 xref: EMBL:BC101104 xref: EMBL:BC101105 xref: EMBL:BC101106 xref: EMBL:BC101107 xref: EMBL:CH471177 xref: EMBL:CR541721 xref: EMBL:X58521 xref: HGNC:HGNC:8066 xref: UniGene:Hs.574492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021718 ! NUP62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007909 name: OR5AC2_human def: "Olfactory receptor 5AC2 gene" [UniProtKB:Q9NZP5] xref: EMBL:AC133439 xref: EMBL:AF179759 xref: HGNC:HGNC:15431 xref: UniGene:Hs.554715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022726 ! O5AC2_HUMAN relationship: codes_for CCO:B0033337 ! A8MTX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007910 name: OR5AK3P_human def: "Putative olfactory receptor 5AK3 gene" [UniProtKB:Q8NH89] synonym: "OR5AK3" EXACT [UniProtKB:Q8NH89] xref: EMBL:AB065497 xref: HGNC:HGNC:15252 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033340 ! O5AK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007911 name: OR5H14_human def: "Olfactory receptor 5H14 gene" [UniProtKB:A6NHG9] xref: EMBL:AB065459 xref: EMBL:AC117460 xref: HGNC:HGNC:31286 xref: UniGene:Hs.554714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022725 ! Q8NHB6_HUMAN relationship: codes_for CCO:B0033342 ! A8MWJ9_HUMAN relationship: codes_for CCO:B0033349 ! O5H14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007912 name: OR5H15_human def: "Olfactory receptor 5H15 gene" [UniProtKB:A6NDH6] xref: EMBL:AC117460 xref: HGNC:HGNC:31287 xref: UniGene:Hs.554713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022729 ! O5H15_HUMAN relationship: codes_for CCO:B0033345 ! A8MXY9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007913 name: OR7E24_human def: "Olfactory receptor 7E24 gene" [UniProtKB:Q6IFN5] synonym: "OR7E24P" EXACT [UniProtKB:Q6IFN5] xref: EMBL:AC006271 xref: EMBL:BK004227 xref: HGNC:HGNC:8396 xref: UniGene:Hs.129832 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022861 ! O7E24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007916 name: OLFML3_human def: "Olfactomedin-like protein 3 precursor gene" [UniProtKB:Q9NRN5] synonym: "PSEC0035" EXACT [UniProtKB:Q9NRN5] synonym: "PSEC0173" EXACT [UniProtKB:Q9NRN5] synonym: "PSEC0244" EXACT [UniProtKB:Q9NRN5] synonym: "UNQ663/PRO1294" EXACT [UniProtKB:Q9NRN5] xref: EMBL:AF201945 xref: EMBL:AK075353 xref: EMBL:AK075479 xref: EMBL:AK075544 xref: EMBL:AK222471 xref: EMBL:AK223221 xref: EMBL:AL731797 xref: EMBL:AY358954 xref: EMBL:AY464015 xref: EMBL:BC009920 xref: HGNC:HGNC:24956 xref: UniGene:Hs.9315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031800 ! OLFL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007919 name: OPN4_human def: "Melanopsin gene" [UniProtKB:Q9UHM6] synonym: "MOP" EXACT [UniProtKB:Q9UHM6] xref: EMBL:AB065730 xref: EMBL:AC067750 xref: EMBL:AF147788 xref: EMBL:BC113558 xref: EMBL:DQ314804 xref: HGNC:HGNC:14449 xref: UniGene:Hs.283922 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033253 ! A6NEB4_HUMAN relationship: codes_for CCO:B0033254 ! OPN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007920 name: RRH_human def: "Visual pigment-like receptor peropsin gene" [UniProtKB:O14718] xref: EMBL:AF012270 xref: EMBL:BK000958 xref: HGNC:HGNC:10450 xref: UniGene:Hs.658310 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033252 ! OPSX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007921 name: OR5H1_human def: "Olfactory receptor 5H1 gene" [UniProtKB:A6NKK0] xref: EMBL:AC117460 xref: EMBL:X64988 xref: HGNC:HGNC:8346 xref: UniGene:Hs.537383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022728 ! OR5H1_HUMAN relationship: codes_for CCO:B0033348 ! A8MVK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007923 name: OR5H6_human def: "Olfactory receptor OR3-11 (Olfactory receptor, family 5, subfamily H, member 6) gene" [UniProtKB:Q6IF88] xref: EMBL:BC137523 xref: EMBL:BC137524 xref: EMBL:BK004374 xref: HGNC:HGNC:14767 xref: UniGene:Hs.554712 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022719 ! Q6IF88_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007924 name: OR5I1_human def: "Olfactory receptor 5I1 gene" [UniProtKB:Q13606] synonym: "OLF1" EXACT [UniProtKB:Q13606] xref: EMBL:BC069093 xref: EMBL:BK004518 xref: EMBL:U56420 xref: HGNC:HGNC:8347 xref: UniGene:Hs.533706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033346 ! OR5I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007925 name: OR5J2_human def: "Olfactory receptor 5J2 gene" [UniProtKB:Q8NH18] xref: EMBL:AB065595 xref: EMBL:BK004517 xref: HGNC:HGNC:19612 xref: UniGene:Hs.537145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029033 ! OR5J2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007926 name: OR5K1_human def: "Olfactory receptor 5K1 gene" [UniProtKB:Q8NHB7] xref: EMBL:AB065458 xref: EMBL:BK004416 xref: EMBL:X64984 xref: HGNC:HGNC:8349 xref: UniGene:Hs.621533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022723 ! OR5K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007927 name: OR5K2_human def: "Olfactory receptor 5K2 gene" [UniProtKB:Q8NHB8] xref: EMBL:AB065457 xref: EMBL:AC074274 xref: EMBL:BK004415 xref: HGNC:HGNC:14774 xref: UniGene:Hs.632558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022731 ! OR5K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007928 name: OR5K3_human def: "Olfactory receptor 5K3 gene" [UniProtKB:A6NET4] xref: EMBL:AC108730 xref: HGNC:HGNC:31290 xref: UniGene:Hs.554709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022721 ! OR5K3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007929 name: OR5K4_human def: "Olfactory receptor 5K4 gene" [UniProtKB:A6NMS3] xref: EMBL:AC108730 xref: EMBL:CH471052 xref: HGNC:HGNC:31291 xref: UniGene:Hs.554710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033341 ! OR5K4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007930 name: OR5T1_human def: "Olfactory receptor 5T1 gene" [UniProtKB:Q8NG75] synonym: "OR5T1P" EXACT [UniProtKB:Q8NG75] xref: EMBL:AB065962 xref: EMBL:BK004336 xref: HGNC:HGNC:14821 xref: UniGene:Hs.553747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033338 ! OR5T1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007932 name: OR5T3_human def: "Putative uncharacterized protein OR5T3 gene" [UniProtKB:A8MW53] xref: EMBL:AC022882 xref: EMBL:BK004335 xref: EMBL:CH471076 xref: HGNC:HGNC:15297 xref: UniGene:Hs.553746 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033335 ! Q6IFC7_HUMAN relationship: codes_for CCO:B0033339 ! A8MW53_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007933 name: OR9Q2_human def: "Olfactory receptor 9Q2 gene" [UniProtKB:Q8NGE9] synonym: "OR9Q2P" EXACT [UniProtKB:Q8NGE9] xref: EMBL:AB065859 xref: HGNC:HGNC:15328 xref: UniGene:Hs.553643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033344 ! OR9Q2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007937 name: OSGIN1_human def: "Oxidative stress-induced growth inhibitor 1 gene" [UniProtKB:Q9UJX0] synonym: "OKL38" EXACT [UniProtKB:Q9UJX0] xref: EMBL:AF191740 xref: EMBL:AF334780 xref: EMBL:AY037158 xref: EMBL:AY258066 xref: EMBL:AY258067 xref: EMBL:AY258068 xref: EMBL:BC032476 xref: HGNC:HGNC:30093 xref: UniGene:Hs.128055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022431 ! OSGI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007941 name: OVOL2_human def: "Transcription factor Ovo-like 2 gene" [UniProtKB:Q9BRP0] synonym: "ZNF339" EXACT [UniProtKB:Q9BRP0] xref: EMBL:AK022284 xref: EMBL:AL079276 xref: EMBL:AL121585 xref: EMBL:AL160411 xref: EMBL:BC006148 xref: EMBL:BT007295 xref: HGNC:HGNC:15804 xref: UniGene:Hs.661013 xref: UniGene:Hs.705784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025365 ! OVOL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007945 name: TP63_human def: "Tumor protein 63 gene" [UniProtKB:Q9H3D4] synonym: "KET" EXACT [UniProtKB:Q9H3D4] synonym: "P63" EXACT [UniProtKB:Q9H3D4] synonym: "P73H" EXACT [UniProtKB:Q9H3D4] synonym: "P73L" EXACT [UniProtKB:Q9H3D4] synonym: "TP73L" EXACT [UniProtKB:Q9H3D4] xref: EMBL:AB010153 xref: EMBL:AB016072 xref: EMBL:AB016073 xref: EMBL:AB042841 xref: EMBL:AF061512 xref: EMBL:AF075428 xref: EMBL:AF075429 xref: EMBL:AF075430 xref: EMBL:AF075431 xref: EMBL:AF075432 xref: EMBL:AF075433 xref: EMBL:AF091627 xref: EMBL:AF116756 xref: EMBL:AF116757 xref: EMBL:AF116758 xref: EMBL:AF116759 xref: EMBL:AF116760 xref: EMBL:AF116761 xref: EMBL:AF116762 xref: EMBL:AF116763 xref: EMBL:AF116764 xref: EMBL:AF116765 xref: EMBL:AF116766 xref: EMBL:AF116767 xref: EMBL:AF116768 xref: EMBL:AF116769 xref: EMBL:AF116770 xref: EMBL:AF116771 xref: EMBL:AF124528 xref: EMBL:AF124529 xref: EMBL:AF124530 xref: EMBL:AF124531 xref: EMBL:AF124532 xref: EMBL:AF124533 xref: EMBL:AF124534 xref: EMBL:AF124535 xref: EMBL:AF124536 xref: EMBL:AF124537 xref: EMBL:AF124538 xref: EMBL:AF124539 xref: EMBL:AF124540 xref: EMBL:AJ315499 xref: EMBL:AY339663 xref: EMBL:AY339664 xref: EMBL:AY341142 xref: EMBL:AY341143 xref: EMBL:AY341144 xref: EMBL:AY341145 xref: EMBL:AY342152 xref: EMBL:AY342153 xref: EMBL:AY342154 xref: EMBL:BC039815 xref: EMBL:Y16961 xref: HGNC:HGNC:15979 xref: UniGene:Hs.137569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022300 ! P63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007946 name: SERBP1_human def: "Plasminogen activator inhibitor 1 RNA-binding protein gene" [UniProtKB:Q8NC51] synonym: "CGI-55" EXACT [UniProtKB:Q8NC51] synonym: "PAIRBP1" EXACT [UniProtKB:Q8NC51] xref: EMBL:AF151813 xref: EMBL:AK074970 xref: EMBL:AK222955 xref: EMBL:AK223138 xref: EMBL:AK312256 xref: EMBL:AL080119 xref: EMBL:AL590559 xref: EMBL:AY032853 xref: EMBL:BC002488 xref: EMBL:BC003049 xref: EMBL:BC008045 xref: EMBL:BC017449 xref: EMBL:BC019273 xref: EMBL:BC020555 xref: EMBL:BC026916 xref: EMBL:CR457383 xref: HGNC:HGNC:17860 xref: UniGene:Hs.702005 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031407 ! PAIRB_HUMAN relationship: codes_for CCO:B0037759 ! Q5VU21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007947 name: PAK2_human def: "Serine/threonine-protein kinase PAK 2 gene" [UniProtKB:Q13177] xref: EMBL:BC069613 xref: EMBL:U24153 xref: EMBL:U25975 xref: HGNC:HGNC:8591 xref: UniGene:Hs.518530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024022 ! PAK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007951 name: PASD1_human def: "PAS domain-containing protein 1 gene" [UniProtKB:Q8IV76] xref: EMBL:AK097552 xref: EMBL:AY270020 xref: EMBL:AY623425 xref: EMBL:BC040301 xref: HGNC:HGNC:20686 xref: UniGene:Hs.160594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026533 ! PASD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007953 name: PCBP1_human def: "Poly(rC)-binding protein 1 gene" [UniProtKB:Q15365] xref: EMBL:BC039742 xref: EMBL:U24223 xref: EMBL:X78137 xref: EMBL:Z29505 xref: HGNC:HGNC:8647 xref: UniGene:Hs.2853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028774 ! PCBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007956 name: PDE7A_human def: "High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A gene" [UniProtKB:Q13946] xref: EMBL:AC055822 xref: EMBL:AC100812 xref: EMBL:L12052 xref: EMBL:U67932 xref: HGNC:HGNC:8791 xref: UniGene:Hs.584788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027478 ! PDE7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007957 name: PDE7B_human def: "cAMP-specific 3',5'-cyclic phosphodiesterase 7B gene" [UniProtKB:Q9NP56] xref: EMBL:AB038040 xref: EMBL:AJ251860 xref: EMBL:AL138828 xref: EMBL:BC075082 xref: EMBL:BC075083 xref: EMBL:EF108327 xref: HGNC:HGNC:8792 xref: UniGene:Hs.652367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027476 ! A1E5M1_HUMAN relationship: codes_for CCO:B0027477 ! PDE7B_HUMAN relationship: codes_for CCO:B0027481 ! Q4VXJ0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007958 name: PDK1_human def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor gene" [UniProtKB:Q15118] xref: EMBL:BC039158 xref: EMBL:L42450 xref: HGNC:HGNC:8809 xref: UniGene:Hs.470633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016807 ! PDK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007959 name: PDK2_human def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor gene" [UniProtKB:Q15119] xref: EMBL:BC005811 xref: EMBL:BC040478 xref: EMBL:L42451 xref: HGNC:HGNC:8810 xref: UniGene:Hs.256667 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016811 ! PDK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007960 name: PDK3_human def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor gene" [UniProtKB:Q15120] xref: EMBL:BC015948 xref: EMBL:L42452 xref: HGNC:HGNC:8811 xref: UniGene:Hs.658190 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016810 ! PDK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007961 name: PDK4_human def: "[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor gene" [UniProtKB:Q16654] xref: EMBL:AC002451 xref: EMBL:BC040239 xref: EMBL:U54617 xref: EMBL:U54618 xref: EMBL:U54619 xref: EMBL:U54620 xref: EMBL:U54621 xref: EMBL:U54622 xref: EMBL:U54623 xref: EMBL:U54624 xref: EMBL:U54625 xref: EMBL:U54626 xref: EMBL:U54627 xref: EMBL:U54628 xref: HGNC:HGNC:8812 xref: UniGene:Hs.8364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016805 ! PDK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007962 name: PDXK_human def: "Pyridoxal kinase gene" [UniProtKB:O00764] synonym: "C21orf124" EXACT [UniProtKB:O00764] synonym: "C21orf97" EXACT [UniProtKB:O00764] synonym: "PKH" EXACT [UniProtKB:O00764] synonym: "PNK" EXACT [UniProtKB:O00764] xref: EMBL:AP001752 xref: EMBL:AY303972 xref: EMBL:BC000123 xref: EMBL:BC005825 xref: EMBL:U89606 xref: HGNC:HGNC:8819 xref: UniGene:Hs.284491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021138 ! PDXK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007963 name: PECAM1_human def: "Platelet endothelial cell adhesion molecule precursor gene" [UniProtKB:P16284] xref: EMBL:AC016489 xref: EMBL:AC138744 xref: EMBL:AF281287 xref: EMBL:AF281288 xref: EMBL:AF281289 xref: EMBL:AF281290 xref: EMBL:AF281291 xref: EMBL:AF281292 xref: EMBL:AF281293 xref: EMBL:AF281294 xref: EMBL:AF281295 xref: EMBL:AF281296 xref: EMBL:AF281297 xref: EMBL:AF281298 xref: EMBL:AF281299 xref: EMBL:AF281300 xref: EMBL:AF281301 xref: EMBL:AF393676 xref: EMBL:AF393677 xref: EMBL:AF393678 xref: EMBL:BC022512 xref: EMBL:BC051822 xref: EMBL:L34631 xref: EMBL:L34637 xref: EMBL:L34638 xref: EMBL:L34639 xref: EMBL:L34640 xref: EMBL:L34641 xref: EMBL:L34642 xref: EMBL:L34644 xref: EMBL:L34645 xref: EMBL:L34649 xref: EMBL:L34655 xref: EMBL:L34657 xref: EMBL:M28526 xref: EMBL:M37780 xref: EMBL:S66450 xref: HGNC:HGNC:8823 xref: UniGene:Hs.514412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026626 ! PECA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007966 name: PEX6_human def: "Peroxisome assembly factor 2 gene" [UniProtKB:Q13608] synonym: "PXAAA1" EXACT [UniProtKB:Q13608] xref: EMBL:AB051076 xref: EMBL:AF108095 xref: EMBL:AF108096 xref: EMBL:AF108097 xref: EMBL:AF108098 xref: EMBL:BC048331 xref: EMBL:D83703 xref: EMBL:U56602 xref: HGNC:HGNC:8859 xref: UniGene:Hs.656425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026912 ! PEX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007967 name: FNTB_human def: "Protein farnesyltransferase subunit beta gene" [UniProtKB:P49356] xref: EMBL:BC020232 xref: EMBL:L00635 xref: EMBL:L10414 xref: HGNC:HGNC:3785 xref: UniGene:Hs.632345 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055422 ! FNTB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007970 name: PDGFRA_human def: "Alpha-type platelet-derived growth factor receptor precursor gene" [UniProtKB:P16234] xref: EMBL:AY229892 xref: EMBL:BC015186 xref: EMBL:D50017 xref: EMBL:M21574 xref: EMBL:M22734 xref: HGNC:HGNC:8803 xref: UniGene:Hs.74615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020505 ! PGFRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007971 name: PDGFRB_human def: "Beta-type platelet-derived growth factor receptor precursor gene" [UniProtKB:P09619] xref: EMBL:BC032224 xref: EMBL:J03278 xref: EMBL:M21616 xref: EMBL:U33172 xref: HGNC:HGNC:8804 xref: UniGene:Hs.509067 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020508 ! PGFRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007972 name: PHF5A_human def: "PHD finger-like domain-containing protein 5A gene" [UniProtKB:Q7RTV0] xref: EMBL:AL008582 xref: EMBL:BC007321 xref: EMBL:BC075808 xref: EMBL:BK000563 xref: EMBL:CR456398 xref: HGNC:HGNC:18000 xref: UniGene:Hs.474980 xref: UniGene:Hs.684916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017947 ! PHF5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007974 name: PILRA_human def: "Paired immunoglobulin-like type 2 receptor alpha precursor gene" [UniProtKB:Q9UKJ1] xref: EMBL:AF161080 xref: EMBL:AJ400841 xref: EMBL:AJ400842 xref: EMBL:AJ400843 xref: EMBL:BC017812 xref: HGNC:HGNC:20396 xref: UniGene:Hs.444407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015779 ! PILRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007975 name: PILRB_human def: "Paired immunoglobulin-like type 2 receptor beta precursor gene" [UniProtKB:Q9UKJ0] synonym: "FDFACT" EXACT [UniProtKB:Q9UKJ0] synonym: "PP1551" EXACT [UniProtKB:Q9UKJ0] xref: EMBL:AF161081 xref: EMBL:AF217981 xref: EMBL:AJ400845 xref: EMBL:AJ400846 xref: EMBL:AL834317 xref: EMBL:AL834336 xref: EMBL:BC050547 xref: HGNC:HGNC:18297 xref: UniGene:Hs.632314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015778 ! PILRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007976 name: PKD2L1_human def: "Polycystic kidney disease 2-like 1 protein gene" [UniProtKB:Q9P0L9] synonym: "PKD2L" EXACT [UniProtKB:Q9P0L9] synonym: "PKDL" EXACT [UniProtKB:Q9P0L9] xref: EMBL:AF053316 xref: EMBL:AF073481 xref: EMBL:AF094827 xref: EMBL:AF153459 xref: EMBL:AF153460 xref: EMBL:AF153461 xref: EMBL:AF153462 xref: EMBL:AF153463 xref: EMBL:AF153464 xref: EMBL:AF153465 xref: EMBL:AF153466 xref: EMBL:AF153467 xref: EMBL:AF153468 xref: EMBL:AF153469 xref: EMBL:AF153470 xref: EMBL:AF153471 xref: EMBL:AF153472 xref: EMBL:AF153473 xref: EMBL:AF153474 xref: EMBL:BC025665 xref: HGNC:HGNC:9011 xref: UniGene:Hs.159241 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016974 ! PK2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007978 name: PLEKHA6_human def: "Pleckstrin homology domain-containing family A member 6 gene" [UniProtKB:Q9Y2H5] synonym: "KIAA0969" EXACT [UniProtKB:Q9Y2H5] synonym: "PEPP3" EXACT [UniProtKB:Q9Y2H5] xref: EMBL:AB023186 xref: EMBL:AL592114 xref: EMBL:BC152475 xref: HGNC:HGNC:17053 xref: UniGene:Hs.253146 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032137 ! PKHA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007981 name: PKN2_human def: "Serine/threonine-protein kinase N2 gene" [UniProtKB:Q16513] synonym: "PRK2" EXACT [UniProtKB:Q16513] synonym: "PRKCL2" EXACT [UniProtKB:Q16513] xref: EMBL:AC119426 xref: EMBL:AL136381 xref: EMBL:CH471097 xref: EMBL:S75548 xref: EMBL:U33052 xref: HGNC:HGNC:9406 xref: UniGene:Hs.440833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021015 ! Q5TBX5_HUMAN relationship: codes_for CCO:B0021020 ! PKN2_HUMAN relationship: codes_for CCO:B0042545 ! B1AL79_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007982 name: PKN3_human def: "Serine/threonine-protein kinase N3 gene" [UniProtKB:Q6P5Z2] synonym: "PKNBETA" EXACT [UniProtKB:Q6P5Z2] xref: EMBL:AB019692 xref: EMBL:AL441992 xref: EMBL:BC062558 xref: HGNC:HGNC:17999 xref: UniGene:Hs.300485 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021018 ! PKN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007983 name: PLD1_human def: "Phospholipase D1 gene" [UniProtKB:Q13393] xref: EMBL:AJ276230 xref: EMBL:BC068976 xref: EMBL:U38545 xref: HGNC:HGNC:9067 xref: UniGene:Hs.382865 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020556 ! PLD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007984 name: PLD2_human def: "Phospholipase D2 gene" [UniProtKB:O14939] xref: EMBL:AF033850 xref: EMBL:AF035483 xref: EMBL:AF038440 xref: EMBL:AF038441 xref: EMBL:BC015033 xref: HGNC:HGNC:9068 xref: UniGene:Hs.104519 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020561 ! PLD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007988 name: LCP1_human def: "Plastin-2 gene" [UniProtKB:P13796] synonym: "PLS2" EXACT [UniProtKB:P13796] xref: EMBL:BC007673 xref: EMBL:BC010271 xref: EMBL:J02923 xref: EMBL:L05492 xref: EMBL:M22300 xref: EMBL:M34426 xref: HGNC:HGNC:6528 xref: UniGene:Hs.381099 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019594 ! PLSL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007989 name: PLS3_human def: "Plastin-3 gene" [UniProtKB:P13797] xref: EMBL:AC005000 xref: EMBL:AL589842 xref: EMBL:BC039049 xref: EMBL:BC056898 xref: EMBL:L05491 xref: EMBL:M22299 xref: EMBL:M34427 xref: HGNC:HGNC:9091 xref: UniGene:Hs.496622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019585 ! PLST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007991 name: POLH_human def: "DNA polymerase eta gene" [UniProtKB:Q9Y253] synonym: "RAD30" EXACT [UniProtKB:Q9Y253] synonym: "RAD30A" EXACT [UniProtKB:Q9Y253] synonym: "XPV" EXACT [UniProtKB:Q9Y253] xref: EMBL:AB024313 xref: EMBL:AB038008 xref: EMBL:AF158185 xref: EMBL:AL353602 xref: EMBL:AL355802 xref: EMBL:AY388614 xref: EMBL:BC015742 xref: HGNC:HGNC:9181 xref: UniGene:Hs.655467 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014914 ! POLH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007992 name: POLK_human def: "DNA polymerase kappa gene" [UniProtKB:Q9UBT6] synonym: "DINB1" EXACT [UniProtKB:Q9UBT6] xref: EMBL:AB027564 xref: EMBL:AB036934 xref: EMBL:AB036935 xref: EMBL:AF163570 xref: EMBL:AF194973 xref: EMBL:AF315602 xref: EMBL:AF318313 xref: EMBL:AK091659 xref: EMBL:AY273797 xref: EMBL:BC014955 xref: EMBL:BC050718 xref: HGNC:HGNC:9183 xref: UniGene:Hs.135756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024762 ! POLK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0007996 name: ACP1_human def: "Low molecular weight phosphotyrosine protein phosphatase gene" [UniProtKB:P24666] xref: EMBL:AC079779 xref: EMBL:AK291861 xref: EMBL:BC007422 xref: EMBL:BT007136 xref: EMBL:CH471053 xref: EMBL:L06508 xref: EMBL:M83653 xref: EMBL:M83654 xref: EMBL:M87545 xref: EMBL:S62884 xref: EMBL:S62885 xref: EMBL:U25847 xref: EMBL:U25848 xref: EMBL:U25849 xref: HGNC:HGNC:122 xref: UniGene:Hs.558296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022236 ! PPAC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008002 name: PPIC_human def: "Peptidyl-prolyl cis-trans isomerase C gene" [UniProtKB:P45877] synonym: "CYPC" EXACT [UniProtKB:P45877] xref: EMBL:BC002678 xref: EMBL:S71018 xref: HGNC:HGNC:9256 xref: UniGene:Hs.110364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033592 ! PPIC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008003 name: PPID_human def: "40 kDa peptidyl-prolyl cis-trans isomerase gene" [UniProtKB:Q08752] synonym: "CYP40" EXACT [UniProtKB:Q08752] synonym: "CYPD" EXACT [UniProtKB:Q08752] xref: EMBL:AY714221 xref: EMBL:BC030707 xref: EMBL:D63861 xref: EMBL:L11667 xref: HGNC:HGNC:9257 xref: UniGene:Hs.581725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022232 ! PPID_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008005 name: PSTPIP1_human def: "Proline-serine-threonine phosphatase-interacting protein 1 gene" [UniProtKB:O43586] synonym: "CD2BP1" EXACT [UniProtKB:O43586] xref: EMBL:AF038602 xref: EMBL:AF038603 xref: EMBL:BC008602 xref: EMBL:U94778 xref: HGNC:HGNC:9580 xref: UniGene:Hs.129758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015018 ! PPIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008008 name: PPRC1_human def: "Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 gene" [UniProtKB:Q5VV67] synonym: "KIAA0595" EXACT [UniProtKB:Q5VV67] xref: EMBL:AB011167 xref: EMBL:AF325193 xref: EMBL:AL500527 xref: EMBL:BC002561 xref: EMBL:BC063806 xref: EMBL:BC063829 xref: HGNC:HGNC:30025 xref: UniGene:Hs.533551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023365 ! PPRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008012 name: CDC40_human def: "Cell division cycle 40 homolog (S. cerevisiae) gene" [UniProtKB:Q5SRM8] synonym: "RP1-71D21.3-004" EXACT [UniProtKB:Q5SRM8] xref: EMBL:AL445068 xref: EMBL:AL671518 xref: HGNC:HGNC:17350 xref: UniGene:Hs.428147 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025091 ! Q5SRN1_HUMAN relationship: codes_for CCO:B0056535 ! Q5SRM8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008013 name: PRPF4B_human def: "Serine/threonine-protein kinase PRP4 homolog gene" [UniProtKB:Q13523] synonym: "KIAA0536" EXACT [UniProtKB:Q13523] synonym: "PRP4" EXACT [UniProtKB:Q13523] synonym: "PRP4H" EXACT [UniProtKB:Q13523] synonym: "PRP4K" EXACT [UniProtKB:Q13523] xref: EMBL:AB011108 xref: EMBL:AF283465 xref: EMBL:AK291244 xref: EMBL:AL033383 xref: EMBL:AL138831 xref: EMBL:AY029347 xref: EMBL:BC009844 xref: EMBL:BC034969 xref: EMBL:CH471087 xref: EMBL:U48736 xref: HGNC:HGNC:17346 xref: UniGene:Hs.159014 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027516 ! PRP4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008014 name: PRPF8_human def: "Pre-mRNA-processing-splicing factor 8 gene" [UniProtKB:Q6P2Q9] synonym: "PRPC8" EXACT [UniProtKB:Q6P2Q9] xref: EMBL:AB007510 xref: EMBL:AF092565 xref: EMBL:BC064370 xref: HGNC:HGNC:17340 xref: UniGene:Hs.181368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020752 ! PRP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008016 name: PRUNE2_human def: "Protein prune homolog 2 gene" [UniProtKB:Q8WUY3] synonym: "C9orf65" EXACT [UniProtKB:Q8WUY3] xref: EMBL:AL390239 xref: EMBL:BC019095 xref: HGNC:HGNC:25209 xref: UniGene:Hs.262857 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021588 ! PRUN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008017 name: PSMA5_human def: "Proteasome subunit alpha type-5 gene" [UniProtKB:P28066] xref: EMBL:AL356735 xref: EMBL:AL390252 xref: EMBL:BC102018 xref: EMBL:BC102019 xref: EMBL:BC102020 xref: EMBL:BC103751 xref: EMBL:CR456847 xref: EMBL:X61970 xref: HGNC:HGNC:9534 xref: UniGene:Hs.485246 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022204 ! PSA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008019 name: PSMA7_human def: "Proteasome subunit alpha type-7 gene" [UniProtKB:O14818] xref: EMBL:AF022815 xref: EMBL:AF054185 xref: EMBL:AL078633 xref: EMBL:BC004427 xref: EMBL:BT007165 xref: HGNC:HGNC:9536 xref: UniGene:Hs.233952 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030768 ! PSA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008020 name: PSMB1_human def: "Proteasome subunit beta type-1 precursor gene" [UniProtKB:P20618] synonym: "PSC5" EXACT [UniProtKB:P20618] xref: EMBL:AL031259 xref: EMBL:BC000508 xref: EMBL:BC020807 xref: EMBL:BT019720 xref: EMBL:D00761 xref: HGNC:HGNC:9537 xref: UniGene:Hs.352768 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030961 ! PSB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008021 name: PSMB2_human def: "Proteasome subunit beta type-2 gene" [UniProtKB:P49721] xref: EMBL:AL157951 xref: EMBL:AL354864 xref: EMBL:AL357035 xref: EMBL:BC101836 xref: EMBL:BC105126 xref: EMBL:BC107901 xref: EMBL:BT007137 xref: EMBL:CR456862 xref: EMBL:D26599 xref: HGNC:HGNC:9539 xref: UniGene:Hs.471441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030800 ! PSB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008022 name: PSMB3_human def: "Proteasome subunit beta type-3 gene" [UniProtKB:P49720] xref: EMBL:BC002570 xref: EMBL:BC013008 xref: EMBL:D26598 xref: HGNC:HGNC:9540 xref: UniGene:Hs.82793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030929 ! PSB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008023 name: PSMB6_human def: "Proteasome subunit beta type-6 precursor gene" [UniProtKB:P28072] synonym: "LMPY" EXACT [UniProtKB:P28072] xref: EMBL:BC000835 xref: EMBL:D29012 xref: EMBL:X61971 xref: HGNC:HGNC:9543 xref: UniGene:Hs.77060 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031015 ! PSB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008024 name: PSMB7_human def: "Proteasome subunit beta type-7 precursor gene" [UniProtKB:Q99436] xref: EMBL:BC000509 xref: EMBL:BC008414 xref: EMBL:BC017116 xref: EMBL:D38048 xref: HGNC:HGNC:9544 xref: UniGene:Hs.213470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034007 ! PSB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008025 name: PSMB9_human def: "Proteasome subunit beta type-9 precursor gene" [UniProtKB:P28065] synonym: "LMP2" EXACT [UniProtKB:P28065] synonym: "RING12" EXACT [UniProtKB:P28065] xref: EMBL:AL669918 xref: EMBL:BC065513 xref: EMBL:S75169 xref: EMBL:U01025 xref: EMBL:X62741 xref: EMBL:X66401 xref: EMBL:X87344 xref: EMBL:Z14977 xref: HGNC:HGNC:9546 xref: UniGene:Hs.654585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031007 ! PSB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008026 name: PSMD13_human def: "26S proteasome non-ATPase regulatory subunit 13 gene" [UniProtKB:Q9UNM6] xref: EMBL:AB009398 xref: EMBL:AF086708 xref: EMBL:AF107837 xref: EMBL:BC001100 xref: EMBL:BC001747 xref: HGNC:HGNC:9558 xref: UniGene:Hs.134688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030887 ! PSD13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008027 name: PSMD7_human def: "26S proteasome non-ATPase regulatory subunit 7 gene" [UniProtKB:P51665] synonym: "MOV34L" EXACT [UniProtKB:P51665] xref: EMBL:BC000338 xref: EMBL:BC012606 xref: EMBL:D50063 xref: HGNC:HGNC:9565 xref: UniGene:Hs.440604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031003 ! PSD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008028 name: PSMD14_human def: "26S proteasome non-ATPase regulatory subunit 14 gene" [UniProtKB:O00487] synonym: "POH1" EXACT [UniProtKB:O00487] xref: EMBL:BC066336 xref: EMBL:U86782 xref: HGNC:HGNC:16889 xref: UniGene:Hs.567410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023606 ! PSDE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008029 name: GINS2_human def: "DNA replication complex GINS protein PSF2 gene" [UniProtKB:Q9Y248] synonym: "CGI-122" EXACT [UniProtKB:Q9Y248] synonym: "DC5" EXACT [UniProtKB:Q9Y248] synonym: "HSPC037" EXACT [UniProtKB:Q9Y248] synonym: "PSF2" EXACT [UniProtKB:Q9Y248] xref: EMBL:AF125098 xref: EMBL:AF151880 xref: EMBL:AF201939 xref: EMBL:AK001275 xref: EMBL:BC003186 xref: EMBL:BC010164 xref: EMBL:BC062444 xref: EMBL:CR457186 xref: HGNC:HGNC:24575 xref: UniGene:Hs.433180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017505 ! PSF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008033 name: PSMD3_human def: "26S proteasome non-ATPase regulatory subunit 3 gene" [UniProtKB:O43242] xref: EMBL:BC000074 xref: EMBL:BC004859 xref: EMBL:BC012302 xref: EMBL:BC020518 xref: EMBL:BC025686 xref: EMBL:BT007217 xref: EMBL:D67025 xref: HGNC:HGNC:9560 xref: UniGene:Hs.12970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021560 ! PSMD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008034 name: PSMD6_human def: "26S proteasome non-ATPase regulatory subunit 6 gene" [UniProtKB:Q15008] synonym: "KIAA0107" EXACT [UniProtKB:Q15008] synonym: "PFAAP4" EXACT [UniProtKB:Q15008] xref: EMBL:AF215935 xref: EMBL:AF530062 xref: EMBL:AY568086 xref: EMBL:BC000630 xref: EMBL:BC000904 xref: EMBL:BC012369 xref: EMBL:D14663 xref: HGNC:HGNC:9564 xref: UniGene:Hs.152536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032651 ! PSMD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008038 name: PTPRN_human def: "Receptor-type tyrosine-protein phosphatase-like N precursor gene" [UniProtKB:Q16849] synonym: "ICA3" EXACT [UniProtKB:Q16849] synonym: "ICA512" EXACT [UniProtKB:Q16849] xref: EMBL:L18983 xref: EMBL:X62899 xref: HGNC:HGNC:9676 xref: UniGene:Hs.89655 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025847 ! PTPRN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008040 name: PURB_human def: "Transcriptional activator protein Pur-beta gene" [UniProtKB:Q96QR8] xref: EMBL:AC004854 xref: EMBL:AY039216 xref: EMBL:BC101735 xref: EMBL:BC101737 xref: HGNC:HGNC:9702 xref: UniGene:Hs.349150 xref: UniGene:Hs.596321 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017945 ! PURB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008041 name: PYDC1_human def: "Pyrin domain-containing protein 1 gene" [UniProtKB:Q8WXC3] synonym: "ASC2" EXACT [UniProtKB:Q8WXC3] synonym: "ASCI" EXACT [UniProtKB:Q8WXC3] synonym: "POP1" EXACT [UniProtKB:Q8WXC3] synonym: "PYC1" EXACT [UniProtKB:Q8WXC3] xref: EMBL:AF454669 xref: EMBL:AF467809 xref: EMBL:AY163727 xref: EMBL:BC105033 xref: EMBL:BC105035 xref: HGNC:HGNC:30261 xref: UniGene:Hs.58314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018189 ! PYDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008042 name: RAB10_human def: "Ras-related protein Rab-10 gene" [UniProtKB:P61026] xref: EMBL:AF086917 xref: EMBL:AF106681 xref: EMBL:AF297660 xref: EMBL:AF498945 xref: EMBL:AK023223 xref: EMBL:AL136650 xref: EMBL:BC000896 xref: EMBL:CR457303 xref: HGNC:HGNC:9759 xref: UniGene:Hs.467960 xref: UniGene:Hs.643072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032549 ! RAB10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008043 name: RAB13_human def: "Ras-related protein Rab-13 gene" [UniProtKB:P51153] synonym: "GIG4" EXACT [UniProtKB:P51153] xref: EMBL:AF498948 xref: EMBL:AL358472 xref: EMBL:AY423722 xref: EMBL:BC000799 xref: EMBL:BC009227 xref: EMBL:BC073168 xref: EMBL:BC094846 xref: EMBL:BT019700 xref: EMBL:BT019701 xref: EMBL:X75593 xref: HGNC:HGNC:9762 xref: UniGene:Hs.151536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032555 ! RAB13_HUMAN relationship: codes_for CCO:B0032556 ! Q504R6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008044 name: RAB5A_human def: "Ras-related protein Rab-5A gene" [UniProtKB:P20339] synonym: "RAB5" EXACT [UniProtKB:P20339] xref: EMBL:AF498936 xref: EMBL:BC001267 xref: EMBL:BC018288 xref: EMBL:M28215 xref: HGNC:HGNC:9783 xref: UniGene:Hs.475663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023551 ! RAB5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008045 name: RAB5B_human def: "Ras-related protein Rab-5B gene" [UniProtKB:P61020] xref: EMBL:AF498937 xref: EMBL:BC032740 xref: EMBL:BC040143 xref: EMBL:BC050558 xref: EMBL:BC056422 xref: EMBL:BC065298 xref: EMBL:BX537408 xref: EMBL:X54871 xref: HGNC:HGNC:9784 xref: UniGene:Hs.567328 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023553 ! RAB5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008046 name: RAB5C_human def: "Ras-related protein Rab-5C gene" [UniProtKB:P51148] synonym: "RABL" EXACT [UniProtKB:P51148] xref: EMBL:AF141304 xref: EMBL:AF498938 xref: EMBL:BC106039 xref: EMBL:BC114439 xref: EMBL:BT019484 xref: EMBL:CH471152 xref: EMBL:CR541901 xref: EMBL:U11293 xref: EMBL:U18420 xref: HGNC:HGNC:9785 xref: UniGene:Hs.701970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023550 ! RAB5C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008047 name: RAB8A_human def: "Ras-related protein Rab-8A gene" [UniProtKB:P61006] synonym: "MEL" EXACT [UniProtKB:P61006] synonym: "RAB8" EXACT [UniProtKB:P61006] xref: EMBL:AF498943 xref: EMBL:BC002977 xref: EMBL:BT007184 xref: EMBL:CH471106 xref: EMBL:CR536583 xref: EMBL:CR542274 xref: EMBL:S53268 xref: EMBL:X56741 xref: HGNC:HGNC:7007 xref: UniGene:Hs.642874 xref: UniGene:Hs.644938 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032548 ! RAB8A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008048 name: RAB8B_human def: "Ras-related protein Rab-8B gene" [UniProtKB:Q92930] xref: EMBL:AB038995 xref: EMBL:BC020654 xref: EMBL:U66624 xref: HGNC:HGNC:30273 xref: UniGene:Hs.389733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032550 ! RAB8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008049 name: CRABP1_human def: "Cellular retinoic acid-binding protein 1 gene" [UniProtKB:P29762] synonym: "RBP5" EXACT [UniProtKB:P29762] xref: EMBL:BC022069 xref: EMBL:CR457017 xref: EMBL:S74445 xref: HGNC:HGNC:2338 xref: UniGene:Hs.346950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034076 ! RABP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008052 name: RALY_human def: "RNA-binding protein Raly gene" [UniProtKB:Q9UKM9] synonym: "HNRPCL2" EXACT [UniProtKB:Q9UKM9] synonym: "P542" EXACT [UniProtKB:Q9UKM9] xref: EMBL:AF148457 xref: EMBL:AL031668 xref: EMBL:BC105018 xref: EMBL:L38696 xref: HGNC:HGNC:15921 xref: UniGene:Hs.136947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021291 ! RALY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008053 name: RAP1B_human def: "Ras-related protein Rap-1b precursor gene" [UniProtKB:P61224] synonym: "OK/SW-cl.11" EXACT [UniProtKB:P61224] xref: EMBL:AB062128 xref: EMBL:AF493913 xref: EMBL:AL080212 xref: EMBL:BC000176 xref: EMBL:BC078173 xref: EMBL:BC095467 xref: EMBL:BT020093 xref: EMBL:CH471054 xref: EMBL:CR407689 xref: EMBL:EF581377 xref: EMBL:X08004 xref: HGNC:HGNC:9857 xref: UniGene:Hs.369920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024410 ! RAP1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008054 name: RAP2A_human def: "Ras-related protein Rap-2a precursor gene" [UniProtKB:P10114] xref: EMBL:AF205602 xref: EMBL:AF493914 xref: EMBL:AL442067 xref: EMBL:BC041333 xref: EMBL:BC070031 xref: EMBL:X12534 xref: HGNC:HGNC:9861 xref: UniGene:Hs.508480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024404 ! RAP2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008055 name: RAP2B_human def: "Ras-related protein Rap-2b precursor gene" [UniProtKB:P61225] xref: EMBL:AF493915 xref: EMBL:BC012362 xref: EMBL:X52987 xref: HGNC:HGNC:9862 xref: UniGene:Hs.98643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024398 ! RAP2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008056 name: RAP2C_human def: "Ras-related protein Rap-2c precursor gene" [UniProtKB:Q9Y3L5] xref: EMBL:AL049685 xref: EMBL:AY298955 xref: EMBL:BC003403 xref: EMBL:Z78022 xref: HGNC:HGNC:21165 xref: UniGene:Hs.119889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024407 ! RAP2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008057 name: RARB_human def: "Retinoic acid receptor beta gene" [UniProtKB:P10826] synonym: "HAP" EXACT [UniProtKB:P10826] synonym: "NR1B2" EXACT [UniProtKB:P10826] xref: EMBL:AF157483 xref: EMBL:BC060794 xref: EMBL:M57445 xref: EMBL:M62303 xref: EMBL:X04014 xref: EMBL:X07282 xref: EMBL:X56849 xref: EMBL:X77664 xref: EMBL:Y00291 xref: HGNC:HGNC:9865 xref: UniGene:Hs.654490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024842 ! RARB_HUMAN relationship: codes_for CCO:B0056055 ! Q15299_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008058 name: RARG_human def: "Retinoic acid receptor gamma gene" [UniProtKB:P13631] synonym: "NR1B3" EXACT [UniProtKB:P13631] xref: EMBL:AJ250835 xref: EMBL:AY013703 xref: EMBL:AY013704 xref: EMBL:BC093727 xref: EMBL:BC093729 xref: EMBL:M24857 xref: EMBL:M32074 xref: EMBL:M38258 xref: EMBL:M57707 xref: EMBL:X57280 xref: HGNC:HGNC:9866 xref: UniGene:Hs.1497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034126 ! RARG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008059 name: RASSF3_human def: "Ras association domain-containing protein 3 gene" [UniProtKB:Q86WH2] xref: EMBL:AY217662 xref: EMBL:AY217663 xref: EMBL:BC100949 xref: EMBL:BC100951 xref: HGNC:HGNC:14271 xref: UniGene:Hs.655521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018956 ! RASF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008060 name: RASSF6_human def: "Ras association domain-containing protein 6 gene" [UniProtKB:Q6ZTQ3] xref: EMBL:AK126346 xref: EMBL:AY217664 xref: EMBL:AY217665 xref: EMBL:BC058835 xref: EMBL:CR749283 xref: HGNC:HGNC:20796 xref: UniGene:Hs.590920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019358 ! RASF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008061 name: RABL2A_human def: "Rab-like protein 2A gene" [UniProtKB:Q9UBK7] xref: EMBL:AF095350 xref: EMBL:AF095351 xref: EMBL:AL078621 xref: HGNC:HGNC:9799 xref: UniGene:Hs.446425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031984 ! RBL2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008062 name: RABL2B_human def: "Rab-like protein 2B gene" [UniProtKB:Q9UNT1] xref: EMBL:AC002055 xref: EMBL:AF095352 xref: EMBL:BC014879 xref: EMBL:BC024281 xref: HGNC:HGNC:9800 xref: UniGene:Hs.584862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031988 ! RBL2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008063 name: RBM11_human def: "Putative RNA-binding protein 11 gene" [UniProtKB:P57052] xref: EMBL:AF519623 xref: EMBL:AK091331 xref: EMBL:AP001660 xref: EMBL:AY077695 xref: EMBL:BC030196 xref: HGNC:HGNC:9897 xref: UniGene:Hs.283828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023760 ! RBM11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008065 name: RBMS1_human def: "RNA-binding motif, single-stranded-interacting protein 1 gene" [UniProtKB:P29558] synonym: "MSSP" EXACT [UniProtKB:P29558] synonym: "MSSP1" EXACT [UniProtKB:P29558] synonym: "SCR2" EXACT [UniProtKB:P29558] xref: EMBL:BC012992 xref: EMBL:BC012993 xref: EMBL:BC018951 xref: EMBL:D28482 xref: EMBL:X64652 xref: HGNC:HGNC:9907 xref: UniGene:Hs.470412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015073 ! RBMS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008073 name: RAD23B_human def: "UV excision repair protein RAD23 homolog B gene" [UniProtKB:P54727] xref: EMBL:AL137852 xref: EMBL:AY165178 xref: EMBL:BC020973 xref: EMBL:D21090 xref: HGNC:HGNC:9813 xref: UniGene:Hs.521640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020493 ! RD23B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008076 name: RAET1G_human def: "Retinoic acid early transcript 1G protein precursor gene" [UniProtKB:Q6H3X3] xref: EMBL:AY172579 xref: EMBL:AY172580 xref: HGNC:HGNC:16795 xref: UniGene:Hs.558792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020481 ! RET1G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008078 name: RFC3_human def: "Replication factor C subunit 3 gene" [UniProtKB:P40938] xref: EMBL:AF484446 xref: EMBL:AL139081 xref: EMBL:BC000149 xref: EMBL:L07541 xref: HGNC:HGNC:9971 xref: UniGene:Hs.115474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026184 ! RFC3_HUMAN relationship: codes_for CCO:B0028704 ! A8MX32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008079 name: RANGAP1_human def: "Ran GTPase-activating protein 1 gene" [UniProtKB:P46060] synonym: "KIAA1835" EXACT [UniProtKB:P46060] synonym: "SD" EXACT [UniProtKB:P46060] xref: EMBL:AB058738 xref: EMBL:AL035681 xref: EMBL:BC014044 xref: EMBL:BC041396 xref: EMBL:CR456557 xref: EMBL:X82260 xref: HGNC:HGNC:9854 xref: UniGene:Hs.183800 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037521 ! RAGP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008086 name: RGS10_human def: "Regulator of G-protein signaling 10 gene" [UniProtKB:O43665] xref: EMBL:AC012468 xref: EMBL:AF045229 xref: EMBL:AF368902 xref: EMBL:AF493934 xref: EMBL:AL355273 xref: EMBL:BC009361 xref: EMBL:CH471066 xref: EMBL:CR457008 xref: HGNC:HGNC:9992 xref: UniGene:Hs.501200 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033333 ! RGS10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008087 name: RGS12_human def: "Regulator of G-protein signaling 12 gene" [UniProtKB:O14924] xref: EMBL:AF030109 xref: EMBL:AF030110 xref: EMBL:AF030111 xref: EMBL:AF030112 xref: EMBL:AF030134 xref: EMBL:AF030135 xref: EMBL:AF030136 xref: EMBL:AF030137 xref: EMBL:AF030138 xref: EMBL:AF030139 xref: EMBL:AF030140 xref: EMBL:AF030141 xref: EMBL:AF030142 xref: EMBL:AF030143 xref: EMBL:AF030144 xref: EMBL:AF030145 xref: EMBL:AF030146 xref: EMBL:AF030147 xref: EMBL:AF030148 xref: EMBL:AF030149 xref: EMBL:AF030151 xref: EMBL:AF030152 xref: EMBL:AF035152 xref: EMBL:BC118594 xref: HGNC:HGNC:9994 xref: UniGene:Hs.527061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033323 ! RGS12_HUMAN relationship: codes_for CCO:B0033334 ! Q147X0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008088 name: RGS13_human def: "Regulator of G-protein signaling 13 gene" [UniProtKB:O14921] xref: EMBL:AF030107 xref: EMBL:AF493935 xref: EMBL:AL136454 xref: EMBL:AL596119 xref: EMBL:AY562947 xref: EMBL:BC016667 xref: EMBL:BC056866 xref: EMBL:BT006929 xref: EMBL:CR536532 xref: HGNC:HGNC:9995 xref: UniGene:Hs.497220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020777 ! RGS13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008089 name: RGS14_human def: "Regulator of G-protein signaling 14 gene" [UniProtKB:O43566] xref: EMBL:AC146507 xref: EMBL:AF037194 xref: EMBL:AF037195 xref: EMBL:AF493936 xref: EMBL:AK123382 xref: EMBL:AY987041 xref: EMBL:BC014094 xref: HGNC:HGNC:9996 xref: UniGene:Hs.9347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033332 ! RGS14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008090 name: RGS16_human def: "Regulator of G-protein signaling 16 gene" [UniProtKB:O15492] synonym: "RGSR" EXACT [UniProtKB:O15492] xref: EMBL:AF009356 xref: EMBL:AF493937 xref: EMBL:AL353778 xref: EMBL:BC006243 xref: EMBL:BT006638 xref: EMBL:U70426 xref: EMBL:U94829 xref: HGNC:HGNC:9997 xref: UniGene:Hs.413297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020768 ! RGS16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008091 name: RGS17_human def: "Regulator of G-protein signaling 17 gene" [UniProtKB:Q9UGC6] xref: EMBL:AF202257 xref: EMBL:AF493938 xref: EMBL:AL080276 xref: EMBL:BC013117 xref: EMBL:BT006997 xref: HGNC:HGNC:14088 xref: UniGene:Hs.166313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026717 ! RGS17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008092 name: RGS18_human def: "Regulator of G-protein signaling 18 gene" [UniProtKB:Q9NS28] synonym: "RGS13" EXACT [UniProtKB:Q9NS28] xref: EMBL:AF076642 xref: EMBL:AF268036 xref: EMBL:AL513175 xref: EMBL:AL596342 xref: EMBL:BC020632 xref: HGNC:HGNC:14261 xref: UniGene:Hs.440890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020787 ! RGS18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008093 name: RGS19_human def: "Regulator of G-protein signaling 19 gene" [UniProtKB:P49795] synonym: "GAIP" EXACT [UniProtKB:P49795] synonym: "GNAI3IP" EXACT [UniProtKB:P49795] xref: EMBL:AF493939 xref: EMBL:AL590548 xref: EMBL:AY585188 xref: EMBL:BC001318 xref: EMBL:BC054337 xref: EMBL:BC063010 xref: EMBL:BT009804 xref: EMBL:X91809 xref: HGNC:HGNC:13735 xref: UniGene:Hs.422336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020776 ! RGS19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008094 name: RGS1_human def: "Regulator of G-protein signaling 1 gene" [UniProtKB:Q08116] synonym: "1R20" EXACT [UniProtKB:Q08116] synonym: "BL34" EXACT [UniProtKB:Q08116] synonym: "IER1" EXACT [UniProtKB:Q08116] xref: EMBL:AF493925 xref: EMBL:AL136987 xref: EMBL:BC015510 xref: EMBL:BT006668 xref: EMBL:S59049 xref: EMBL:X73427 xref: HGNC:HGNC:9991 xref: UniGene:Hs.75256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020780 ! RGS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008095 name: RGS20_human def: "Regulator of G-protein signaling 20 gene" [UniProtKB:O76081] synonym: "RGSZ1" EXACT [UniProtKB:O76081] synonym: "ZGAP1" EXACT [UniProtKB:O76081] xref: EMBL:AF060877 xref: EMBL:AF074979 xref: EMBL:AF366054 xref: EMBL:AF366055 xref: EMBL:AF366056 xref: EMBL:AF366057 xref: EMBL:AF493940 xref: EMBL:AY046538 xref: EMBL:BC015614 xref: EMBL:BC063490 xref: HGNC:HGNC:14600 xref: UniGene:Hs.368733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020764 ! RGS20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008096 name: RGS21_human def: "Regulator of G-protein signaling 21 gene" [UniProtKB:Q2M5E4] xref: EMBL:AY643711 xref: HGNC:HGNC:26839 xref: UniGene:Hs.558673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020765 ! RGS21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008097 name: RGS3_human def: "Regulator of G-protein signaling 3 gene" [UniProtKB:P49796] xref: EMBL:AF463495 xref: EMBL:AF490839 xref: EMBL:AF490840 xref: EMBL:AF493927 xref: EMBL:AF493941 xref: EMBL:AK074977 xref: EMBL:AK128127 xref: EMBL:AL137066 xref: EMBL:AL162727 xref: EMBL:AL359455 xref: EMBL:AY585192 xref: EMBL:BC042555 xref: EMBL:U27655 xref: HGNC:HGNC:9999 xref: UniGene:Hs.494875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020771 ! RGS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008098 name: RGS4_human def: "Regulator of G-protein signaling 4 gene" [UniProtKB:P49798] xref: EMBL:AF493928 xref: EMBL:AL583850 xref: EMBL:BC000737 xref: EMBL:BC051869 xref: EMBL:BT007025 xref: EMBL:U27768 xref: HGNC:HGNC:10000 xref: UniGene:Hs.386726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026710 ! RGS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008099 name: RGS5_human def: "Regulator of G-protein signaling 5 gene" [UniProtKB:O15539] xref: EMBL:AB008109 xref: EMBL:AF030108 xref: EMBL:AF159570 xref: EMBL:AF493929 xref: EMBL:AL451063 xref: EMBL:AL499616 xref: EMBL:AL583850 xref: EMBL:BC030059 xref: HGNC:HGNC:10001 xref: UniGene:Hs.24950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020766 ! RGS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008100 name: RGS8_human def: "Regulator of G-protein signaling 8 gene" [UniProtKB:P57771] xref: EMBL:AF297015 xref: EMBL:AF300649 xref: EMBL:AL353778 xref: EMBL:BC069677 xref: EMBL:BC069718 xref: EMBL:BC103865 xref: EMBL:BC103866 xref: EMBL:BC103867 xref: HGNC:HGNC:16810 xref: UniGene:Hs.20982 xref: UniGene:Hs.458417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020790 ! RGS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008101 name: DLC1_human def: "Rho GTPase-activating protein 7 gene" [UniProtKB:Q96QB1] synonym: "ARHGAP7" EXACT [UniProtKB:Q96QB1] synonym: "KIAA1723" EXACT [UniProtKB:Q96QB1] synonym: "STARD12" EXACT [UniProtKB:Q96QB1] xref: EMBL:AB051510 xref: EMBL:AF026219 xref: EMBL:AF035119 xref: EMBL:AF408768 xref: EMBL:AF408769 xref: EMBL:AF408770 xref: EMBL:AF408771 xref: EMBL:AF408772 xref: EMBL:AF408773 xref: EMBL:AF408774 xref: EMBL:AF408775 xref: EMBL:AF408776 xref: EMBL:AF408777 xref: EMBL:AF408778 xref: EMBL:AF408779 xref: EMBL:AF408780 xref: EMBL:AF408781 xref: EMBL:BC054511 xref: HGNC:HGNC:2897 xref: UniGene:Hs.134296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016789 ! Q7Z5R8_HUMAN relationship: codes_for CCO:B0016790 ! RHG07_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008102 name: ARHGAP28_human def: "Rho GTPase-activating protein 28 gene" [UniProtKB:Q9P2N2] synonym: "KIAA1314" EXACT [UniProtKB:Q9P2N2] xref: EMBL:AB037735 xref: EMBL:AK001174 xref: EMBL:AP005205 xref: EMBL:AP005210 xref: EMBL:BC033668 xref: EMBL:BC065274 xref: HGNC:HGNC:25509 xref: UniGene:Hs.183114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034094 ! RHG28_HUMAN relationship: codes_for CCO:B0034095 ! A8MQB7_HUMAN relationship: codes_for CCO:B0034099 ! A8MU88_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008103 name: RING1_human def: "E3 ubiquitin-protein ligase RING1 gene" [UniProtKB:Q06587] synonym: "RNF1" EXACT [UniProtKB:Q06587] xref: EMBL:AL031228 xref: EMBL:AL645940 xref: EMBL:AL713971 xref: EMBL:AL844527 xref: EMBL:BC002922 xref: EMBL:BC051866 xref: EMBL:BT007352 xref: EMBL:Z14000 xref: HGNC:HGNC:10018 xref: UniGene:Hs.631989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020553 ! RING1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008104 name: RNF2_human def: "E3 ubiquitin-protein ligase RING2 gene" [UniProtKB:Q99496] synonym: "BAP1" EXACT [UniProtKB:Q99496] synonym: "DING" EXACT [UniProtKB:Q99496] synonym: "HIPI3" EXACT [UniProtKB:Q99496] synonym: "RING1B" EXACT [UniProtKB:Q99496] xref: EMBL:AF141327 xref: EMBL:AL109865 xref: EMBL:BC012583 xref: EMBL:Y10571 xref: HGNC:HGNC:10061 xref: UniGene:Hs.591490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020552 ! RING2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008107 name: RRM2B_human def: "Ribonucleoside-diphosphate reductase subunit M2 B gene" [UniProtKB:Q7LG56] synonym: "P53R2" EXACT [UniProtKB:Q7LG56] xref: EMBL:AB036063 xref: EMBL:AB036532 xref: EMBL:AB163437 xref: EMBL:AB163438 xref: EMBL:AB166669 xref: EMBL:AB166670 xref: EMBL:AB166671 xref: EMBL:AK001965 xref: EMBL:AL137348 xref: EMBL:BC042468 xref: EMBL:BC108261 xref: EMBL:BC117496 xref: EMBL:BC130628 xref: EMBL:DQ027001 xref: HGNC:HGNC:17296 xref: UniGene:Hs.512592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030758 ! RIR2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008108 name: RRM2_human def: "Ribonucleoside-diphosphate reductase subunit M2 gene" [UniProtKB:P31350] synonym: "RR2" EXACT [UniProtKB:P31350] xref: EMBL:AC104794 xref: EMBL:AY032750 xref: EMBL:BC001886 xref: EMBL:BC030154 xref: EMBL:S40301 xref: EMBL:X59618 xref: HGNC:HGNC:10452 xref: UniGene:Hs.226390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030757 ! RIR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008109 name: RPL13_human def: "60S ribosomal protein L13 gene" [UniProtKB:P26373] synonym: "BBC1" EXACT [UniProtKB:P26373] synonym: "OK/SW-cl.46" EXACT [UniProtKB:P26373] xref: EMBL:AB062392 xref: EMBL:BC004954 xref: EMBL:BC007345 xref: EMBL:BC007563 xref: EMBL:BC007805 xref: EMBL:BC010994 xref: EMBL:BC013078 xref: EMBL:BC014167 xref: EMBL:BC020804 xref: EMBL:BC027463 xref: EMBL:BC063378 xref: EMBL:BC106058 xref: EMBL:X64707 xref: HGNC:HGNC:10303 xref: UniGene:Hs.410817 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033633 ! RL13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008114 name: RND1_human def: "Rho-related GTP-binding protein Rho6 precursor gene" [UniProtKB:Q92730] synonym: "RHO6" EXACT [UniProtKB:Q92730] xref: EMBL:AB040147 xref: EMBL:AF498967 xref: EMBL:BC026356 xref: EMBL:Y07923 xref: HGNC:HGNC:18314 xref: UniGene:Hs.124940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030278 ! RND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008115 name: RND2_human def: "Rho-related GTP-binding protein RhoN precursor gene" [UniProtKB:P52198] synonym: "ARHN" EXACT [UniProtKB:P52198] synonym: "RHO7" EXACT [UniProtKB:P52198] xref: EMBL:AF498968 xref: EMBL:BC094842 xref: EMBL:BC104986 xref: EMBL:BC104990 xref: EMBL:BT019394 xref: EMBL:L78833 xref: EMBL:X95456 xref: HGNC:HGNC:18315 xref: UniGene:Hs.603111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030280 ! RND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008116 name: RND3_human def: "Rho-related GTP-binding protein RhoE precursor gene" [UniProtKB:P61587] synonym: "ARHE" EXACT [UniProtKB:P61587] synonym: "RHO8" EXACT [UniProtKB:P61587] synonym: "RHOE" EXACT [UniProtKB:P61587] xref: EMBL:AF498969 xref: EMBL:BC012513 xref: EMBL:BT006769 xref: EMBL:S82240 xref: EMBL:X95282 xref: EMBL:X97758 xref: HGNC:HGNC:671 xref: UniGene:Hs.660729 xref: UniGene:Hs.6838 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030277 ! RND3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008119 name: RORA_human def: "Nuclear receptor ROR-alpha gene" [UniProtKB:P35398] synonym: "NR1F1" EXACT [UniProtKB:P35398] synonym: "RZRA" EXACT [UniProtKB:P35398] xref: EMBL:BC008831 xref: EMBL:BC100987 xref: EMBL:BC100988 xref: EMBL:BC100989 xref: EMBL:BC100990 xref: EMBL:CH471082 xref: EMBL:L14611 xref: EMBL:U04897 xref: EMBL:U04898 xref: EMBL:U04899 xref: HGNC:HGNC:10258 xref: UniGene:Hs.695914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019065 ! Q495X4_HUMAN relationship: codes_for CCO:B0019067 ! RORA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008120 name: RORB_human def: "Nuclear receptor ROR-beta gene" [UniProtKB:Q92753] synonym: "NR1F2" EXACT [UniProtKB:Q92753] synonym: "RZRB" EXACT [UniProtKB:Q92753] xref: EMBL:AL137018 xref: EMBL:BX647070 xref: EMBL:Y08639 xref: HGNC:HGNC:10259 xref: UniGene:Hs.494178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019068 ! RORB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008121 name: POLR1D_human def: "DNA-directed RNA polymerases I and III subunit RPAC2 gene" [UniProtKB:Q9Y2S0] xref: EMBL:AF077044 xref: EMBL:AK311833 xref: EMBL:AL136439 xref: EMBL:BC000889 xref: EMBL:BC015319 xref: EMBL:BC018528 xref: EMBL:CH471075 xref: HGNC:HGNC:20422 xref: UniGene:Hs.507584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021709 ! RPAC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008123 name: POLR2D_human def: "DNA-directed RNA polymerase II subunit RPB4 gene" [UniProtKB:O15514] xref: EMBL:BC017205 xref: EMBL:BC093795 xref: EMBL:BC093797 xref: EMBL:U85510 xref: EMBL:U89387 xref: HGNC:HGNC:9191 xref: UniGene:Hs.705491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030954 ! RPB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008126 name: RRAS2_human def: "Ras-related protein R-Ras2 precursor gene" [UniProtKB:P62070] synonym: "TC21" EXACT [UniProtKB:P62070] xref: EMBL:AF493924 xref: EMBL:BC013106 xref: EMBL:M31468 xref: HGNC:HGNC:17271 xref: UniGene:Hs.502004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018011 ! RRAS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008127 name: RRAS_human def: "Ras-related protein R-Ras precursor gene" [UniProtKB:P10301] xref: EMBL:AF493920 xref: EMBL:BC016286 xref: EMBL:BC016318 xref: EMBL:BT006805 xref: EMBL:M14948 xref: EMBL:M14949 xref: HGNC:HGNC:10447 xref: UniGene:Hs.515536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018007 ! RRAS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008130 name: RPS25_human def: "40S ribosomal protein S25 gene" [UniProtKB:P62851] xref: EMBL:AB061844 xref: EMBL:BC003537 xref: EMBL:BC004294 xref: EMBL:BC004986 xref: EMBL:M64716 xref: HGNC:HGNC:10413 xref: UniGene:Hs.512676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034271 ! RS25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008132 name: RPS27_human def: "40S ribosomal protein S27 gene" [UniProtKB:P42677] synonym: "MPS1" EXACT [UniProtKB:P42677] xref: EMBL:AB007162 xref: EMBL:AB061845 xref: EMBL:BC002658 xref: EMBL:BC070219 xref: EMBL:L19739 xref: EMBL:U57847 xref: HGNC:HGNC:10416 xref: UniGene:Hs.546291 xref: UniGene:Hs.654475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033001 ! RS27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008133 name: RPS3_human def: "40S ribosomal protein S3 gene" [UniProtKB:P23396] synonym: "OK/SW-cl.26" EXACT [UniProtKB:P23396] xref: EMBL:AB061838 xref: EMBL:AB062288 xref: EMBL:AY791291 xref: EMBL:BC003137 xref: EMBL:BC003577 xref: EMBL:BC013196 xref: EMBL:BC034149 xref: EMBL:BC071917 xref: EMBL:BC100284 xref: EMBL:L16016 xref: EMBL:S42658 xref: EMBL:U14990 xref: EMBL:U14991 xref: EMBL:U14992 xref: EMBL:X55715 xref: HGNC:HGNC:10420 xref: UniGene:Hs.546286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030969 ! RS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008136 name: RUFY3_human def: "Protein RUFY3 gene" [UniProtKB:Q7L099] synonym: "KIAA0871" EXACT [UniProtKB:Q7L099] xref: EMBL:AB020678 xref: EMBL:AF112221 xref: EMBL:BC051716 xref: HGNC:HGNC:30285 xref: UniGene:Hs.7972 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033364 ! RUFY3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008137 name: RUNX1_human def: "Runt-related transcription factor 1 gene" [UniProtKB:Q01196] synonym: "AML1" EXACT [UniProtKB:Q01196] synonym: "CBFA2" EXACT [UniProtKB:Q01196] xref: EMBL:AF025841 xref: EMBL:AJ229043 xref: EMBL:AP000330 xref: EMBL:AP000331 xref: EMBL:BC110828 xref: EMBL:D10570 xref: EMBL:D13979 xref: EMBL:D14822 xref: EMBL:D14823 xref: EMBL:D43967 xref: EMBL:D43968 xref: EMBL:D43969 xref: EMBL:D89788 xref: EMBL:D89789 xref: EMBL:D89790 xref: EMBL:L21756 xref: EMBL:L34598 xref: EMBL:S50186 xref: EMBL:S60998 xref: EMBL:S69002 xref: EMBL:S74092 xref: EMBL:S76345 xref: EMBL:S76346 xref: EMBL:S76350 xref: EMBL:S78158 xref: EMBL:S78159 xref: EMBL:S78496 xref: EMBL:U19601 xref: EMBL:X79549 xref: EMBL:X90976 xref: EMBL:X90979 xref: HGNC:HGNC:10471 xref: UniGene:Hs.149261 xref: UniGene:Hs.612648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033618 ! Q2TAM6_HUMAN relationship: codes_for CCO:B0033619 ! RUNX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008138 name: RUNX2_human def: "Runt-related transcription factor 2 gene" [UniProtKB:Q13950] synonym: "AML3" EXACT [UniProtKB:Q13950] synonym: "CBFA1" EXACT [UniProtKB:Q13950] synonym: "OSF2" EXACT [UniProtKB:Q13950] synonym: "PEBP2A" EXACT [UniProtKB:Q13950] xref: EMBL:AF001443 xref: EMBL:AF001444 xref: EMBL:AF001445 xref: EMBL:AF001446 xref: EMBL:AF001447 xref: EMBL:AF001448 xref: EMBL:AF001449 xref: EMBL:AF001450 xref: EMBL:AF053949 xref: EMBL:AF053952 xref: EMBL:AL096865 xref: EMBL:AL161907 xref: EMBL:AL358135 xref: EMBL:L40992 xref: HGNC:HGNC:10472 xref: UniGene:Hs.535845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033620 ! Q5T802_HUMAN relationship: codes_for CCO:B0033622 ! RUNX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008139 name: RXRA_human def: "Retinoic acid receptor RXR-alpha gene" [UniProtKB:P19793] synonym: "NR2B1" EXACT [UniProtKB:P19793] xref: EMBL:DQ303444 xref: EMBL:X52773 xref: HGNC:HGNC:10477 xref: UniGene:Hs.590886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024886 ! RXRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008140 name: RXRB_human def: "Retinoic acid receptor RXR-beta gene" [UniProtKB:P28702] synonym: "NR2B2" EXACT [UniProtKB:P28702] xref: EMBL:AF065396 xref: EMBL:AF120161 xref: EMBL:AL031228 xref: EMBL:AL645940 xref: EMBL:AL662824 xref: EMBL:AL844527 xref: EMBL:BC001167 xref: EMBL:CR354565 xref: EMBL:CR759733 xref: EMBL:CR936877 xref: EMBL:M84820 xref: EMBL:X63522 xref: EMBL:X66424 xref: HGNC:HGNC:10478 xref: UniGene:Hs.388034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024878 ! RXRB_HUMAN relationship: codes_for CCO:B0024884 ! Q5STQ1_HUMAN relationship: codes_for CCO:B0030185 ! A8MS99_HUMAN relationship: codes_for CCO:B0041960 ! A2ABB0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008141 name: RXRG_human def: "Retinoic acid receptor RXR-gamma gene" [UniProtKB:P48443] synonym: "NR2B3" EXACT [UniProtKB:P48443] xref: EMBL:AL160058 xref: EMBL:BC012063 xref: EMBL:CH471067 xref: EMBL:CR456705 xref: EMBL:U38480 xref: HGNC:HGNC:10479 xref: UniGene:Hs.26550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024881 ! RXRG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008146 name: S100A4_human def: "Protein S100-A4 gene" [UniProtKB:P26447] synonym: "CAPL" EXACT [UniProtKB:P26447] synonym: "MTS1" EXACT [UniProtKB:P26447] xref: EMBL:BC000838 xref: EMBL:BC016300 xref: EMBL:BX470102 xref: EMBL:CR450345 xref: EMBL:M80563 xref: EMBL:Z18950 xref: EMBL:Z33457 xref: HGNC:HGNC:10494 xref: UniGene:Hs.654444 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019310 ! S10A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008153 name: SLC26A5_human def: "Prestin gene" [UniProtKB:P58743] synonym: "PRES" EXACT [UniProtKB:P58743] xref: EMBL:AC005064 xref: EMBL:AF523354 xref: EMBL:AY256823 xref: EMBL:AY256824 xref: EMBL:AY256825 xref: HGNC:HGNC:9359 xref: UniGene:Hs.585146 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034023 ! S26A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008161 name: SEC61A1_human def: "Protein transport protein Sec61 subunit alpha isoform 1 gene" [UniProtKB:P61619] synonym: "SEC61A" EXACT [UniProtKB:P61619] xref: EMBL:AF077032 xref: EMBL:AF084458 xref: EMBL:AF346602 xref: EMBL:AK074907 xref: EMBL:AK074928 xref: EMBL:AK075148 xref: EMBL:AL831940 xref: EMBL:AL832821 xref: HGNC:HGNC:18276 xref: UniGene:Hs.518236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027154 ! S61A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008162 name: SEC61A2_human def: "Protein transport protein Sec61 subunit alpha isoform 2 gene" [UniProtKB:Q9H9S3] xref: EMBL:AF346603 xref: EMBL:AK022640 xref: HGNC:HGNC:17702 xref: UniGene:Hs.112955 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027148 ! S61A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008166 name: SCAND1_human def: "SCAN domain-containing protein 1 gene" [UniProtKB:P57086] synonym: "SDP1" EXACT [UniProtKB:P57086] xref: EMBL:AF204271 xref: EMBL:AL109965 xref: EMBL:BC000785 xref: EMBL:BC036709 xref: EMBL:BC041022 xref: HGNC:HGNC:10566 xref: UniGene:Hs.584909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019498 ! SCND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008167 name: SCAND2_human def: "SCAN domain-containing protein 2 gene" [UniProtKB:Q9GZW5] xref: EMBL:AF229246 xref: EMBL:AF244812 xref: EMBL:AK022844 xref: EMBL:BC011547 xref: EMBL:BC012929 xref: EMBL:BC063836 xref: HGNC:HGNC:10567 xref: UniGene:Hs.658114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021156 ! SCND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008174 name: SETD1B_human def: "Histone-lysine N-methyltransferase SETD1B gene" [UniProtKB:Q9UPS6] synonym: "KIAA1076" EXACT [UniProtKB:Q9UPS6] synonym: "KMT2G" EXACT [UniProtKB:Q9UPS6] synonym: "SET1B" EXACT [UniProtKB:Q9UPS6] xref: EMBL:AB028999 xref: EMBL:AC084018 xref: HGNC:HGNC:29187 xref: UniGene:Hs.507122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034353 ! SET1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008176 name: SF3B3_human def: "Splicing factor 3B subunit 3 gene" [UniProtKB:Q15393] synonym: "KIAA0017" EXACT [UniProtKB:Q15393] synonym: "SAP130" EXACT [UniProtKB:Q15393] xref: EMBL:AJ001443 xref: EMBL:AL110251 xref: EMBL:BC000463 xref: EMBL:BC003146 xref: EMBL:BC009780 xref: EMBL:BC068974 xref: EMBL:D13642 xref: EMBL:D87686 xref: HGNC:HGNC:10770 xref: UniGene:Hs.514435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026181 ! SF3B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008180 name: SGK2_human def: "Serine/threonine-protein kinase Sgk2 gene" [UniProtKB:Q9HBY8] xref: EMBL:AF169034 xref: EMBL:AF186470 xref: EMBL:AY987010 xref: EMBL:BC014037 xref: EMBL:BC065511 xref: EMBL:BT020098 xref: EMBL:Z98752 xref: HGNC:HGNC:13900 xref: UniGene:Hs.300863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033210 ! SGK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008184 name: SIPA1L2_human def: "Signal-induced proliferation-associated 1-like protein 2 gene" [UniProtKB:Q9P2F8] synonym: "KIAA1389" EXACT [UniProtKB:Q9P2F8] xref: EMBL:AB037810 xref: EMBL:AK022852 xref: EMBL:AK093191 xref: EMBL:AL157409 xref: EMBL:AL356965 xref: EMBL:BC013119 xref: EMBL:BC082251 xref: HGNC:HGNC:23800 xref: UniGene:Hs.268774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023489 ! SI1L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008186 name: SLA2_human def: "Src-like-adapter 2 gene" [UniProtKB:Q9H6Q3] synonym: "C20orf156" EXACT [UniProtKB:Q9H6Q3] synonym: "SLAP2" EXACT [UniProtKB:Q9H6Q3] xref: EMBL:AF290985 xref: EMBL:AF290986 xref: EMBL:AF326353 xref: EMBL:AK025645 xref: EMBL:AL031662 xref: EMBL:AL050318 xref: EMBL:BC042041 xref: HGNC:HGNC:17329 xref: UniGene:Hs.705432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022559 ! SLAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008187 name: SMAP1_human def: "Stromal membrane-associated protein 1 gene" [UniProtKB:Q8IYB5] xref: EMBL:AF442495 xref: EMBL:AK023221 xref: EMBL:AK222711 xref: EMBL:AL121961 xref: EMBL:AL354943 xref: EMBL:AL591049 xref: EMBL:AL833906 xref: EMBL:AY055003 xref: EMBL:AY055004 xref: EMBL:AY055005 xref: EMBL:AY055006 xref: EMBL:AY055007 xref: EMBL:AY055008 xref: EMBL:AY055009 xref: EMBL:AY055010 xref: EMBL:AY055011 xref: EMBL:AY055012 xref: EMBL:AY055013 xref: EMBL:AY055014 xref: EMBL:AY055015 xref: EMBL:BC008672 xref: EMBL:BC028074 xref: EMBL:BC036123 xref: HGNC:HGNC:19651 xref: UniGene:Hs.485717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015543 ! SMAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008188 name: SMAP2_human def: "Stromal membrane-associated protein 2 gene" [UniProtKB:Q8WU79] synonym: "SMAP1L" EXACT [UniProtKB:Q8WU79] xref: EMBL:AL031985 xref: EMBL:AL133206 xref: EMBL:AL137764 xref: EMBL:BC014512 xref: EMBL:BC021133 xref: HGNC:HGNC:25082 xref: UniGene:Hs.15200 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033514 ! SMAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008190 name: SNRPD1_human def: "Small nuclear ribonucleoprotein Sm D1 gene" [UniProtKB:P62314] xref: EMBL:BC001721 xref: EMBL:BC072427 xref: EMBL:CR542239 xref: EMBL:J03798 xref: EMBL:L36182 xref: EMBL:L36186 xref: EMBL:L36187 xref: EMBL:L36188 xref: HGNC:HGNC:11158 xref: UniGene:Hs.464734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023192 ! SMD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008191 name: SNRPD2_human def: "Small nuclear ribonucleoprotein Sm D2 gene" [UniProtKB:P62316] synonym: "SNRPD1" EXACT [UniProtKB:P62316] xref: EMBL:AC007191 xref: EMBL:BC000486 xref: EMBL:BC001930 xref: EMBL:U15008 xref: HGNC:HGNC:11159 xref: UniGene:Hs.515472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018244 ! SMD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008192 name: SNF8_human def: "Vacuolar-sorting protein SNF8 gene" [UniProtKB:Q96H20] synonym: "EAP30" EXACT [UniProtKB:Q96H20] xref: EMBL:AF156102 xref: EMBL:BC008976 xref: EMBL:BC038830 xref: HGNC:HGNC:17028 xref: UniGene:Hs.127249 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018982 ! SNF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008194 name: SNX5_human def: "Sorting nexin-5 gene" [UniProtKB:Q9Y5X3] xref: EMBL:AF121855 xref: EMBL:AK001793 xref: EMBL:AL121585 xref: EMBL:BC000100 xref: EMBL:BC093623 xref: EMBL:BC093980 xref: HGNC:HGNC:14969 xref: UniGene:Hs.316890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026585 ! SNX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008195 name: SNX6_human def: "Sorting nexin-6 gene" [UniProtKB:Q9UNH7] xref: EMBL:AF121856 xref: EMBL:U83194 xref: HGNC:HGNC:14970 xref: UniGene:Hs.583855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026583 ! SNX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008196 name: SOD1_human def: "Superoxide dismutase [Cu-Zn] gene" [UniProtKB:P00441] xref: EMBL:AK312116 xref: EMBL:AP000253 xref: EMBL:AY049787 xref: EMBL:AY450286 xref: EMBL:AY835629 xref: EMBL:BC001034 xref: EMBL:BT006676 xref: EMBL:CH471079 xref: EMBL:CR450355 xref: EMBL:CR541742 xref: EMBL:EF151142 xref: EMBL:L44135 xref: EMBL:L44136 xref: EMBL:L44137 xref: EMBL:L44139 xref: EMBL:L44746 xref: EMBL:L46374 xref: EMBL:L46375 xref: EMBL:X01780 xref: EMBL:X01781 xref: EMBL:X01782 xref: EMBL:X01783 xref: EMBL:X01784 xref: EMBL:X02317 xref: EMBL:X95228 xref: HGNC:HGNC:11179 xref: UniGene:Hs.443914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033014 ! SODC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008197 name: SOD2_human def: "Superoxide dismutase [Mn], mitochondrial precursor gene" [UniProtKB:P04179] xref: EMBL:AL135914 xref: EMBL:AY267901 xref: EMBL:BC012423 xref: EMBL:BT006967 xref: EMBL:M36693 xref: EMBL:S77127 xref: EMBL:X07834 xref: EMBL:X14322 xref: EMBL:X15132 xref: EMBL:X59445 xref: EMBL:Y00472 xref: EMBL:Y00985 xref: HGNC:HGNC:11180 xref: UniGene:Hs.487046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033778 ! SODM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008198 name: SRI_human def: "Sorcin gene" [UniProtKB:P30626] xref: EMBL:BC011025 xref: EMBL:L12387 xref: EMBL:M32886 xref: HGNC:HGNC:11292 xref: UniGene:Hs.489040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026103 ! SORCN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008199 name: SOX11_human def: "Transcription factor SOX-11 gene" [UniProtKB:P35716] xref: EMBL:AB028641 xref: EMBL:U23752 xref: EMBL:X73038 xref: HGNC:HGNC:11191 xref: UniGene:Hs.432638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020254 ! SOX11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008200 name: SOX12_human def: "SOX-12 protein gene" [UniProtKB:O15370] synonym: "SOX22" EXACT [UniProtKB:O15370] xref: EMBL:AL034548 xref: EMBL:BC067361 xref: EMBL:U35612 xref: HGNC:HGNC:11198 xref: UniGene:Hs.43627 xref: UniGene:Hs.700890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020253 ! SOX12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008201 name: SOX14_human def: "Transcription factor SOX-14 gene" [UniProtKB:O95416] synonym: "SOX28" EXACT [UniProtKB:O95416] xref: EMBL:AF032451 xref: EMBL:AF107043 xref: EMBL:AF193436 xref: EMBL:AJ006230 xref: EMBL:BC106729 xref: EMBL:BC106730 xref: HGNC:HGNC:11193 xref: UniGene:Hs.248184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020267 ! SOX14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008202 name: SOX15_human def: "SOX-15 protein gene" [UniProtKB:O60248] synonym: "SOX12" EXACT [UniProtKB:O60248] synonym: "SOX20" EXACT [UniProtKB:O60248] synonym: "SOX26" EXACT [UniProtKB:O60248] synonym: "SOX27" EXACT [UniProtKB:O60248] xref: EMBL:AB006867 xref: EMBL:AB025355 xref: EMBL:AJ006222 xref: EMBL:BC000985 xref: EMBL:BC072003 xref: EMBL:X73039 xref: HGNC:HGNC:11196 xref: UniGene:Hs.95582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020283 ! SOX15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008203 name: SOX18_human def: "Transcription factor SOX-18 gene" [UniProtKB:P35713] xref: EMBL:AB033888 xref: EMBL:AF270652 xref: EMBL:AJ243896 xref: EMBL:AL355803 xref: EMBL:BC038590 xref: EMBL:BC073971 xref: EMBL:BC111390 xref: EMBL:X65664 xref: HGNC:HGNC:11194 xref: UniGene:Hs.8619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020259 ! SOX18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008204 name: SOX1_human def: "SOX-1 protein gene" [UniProtKB:O00570] xref: EMBL:AL138691 xref: EMBL:CH471085 xref: EMBL:Y13436 xref: HGNC:HGNC:11189 xref: UniGene:Hs.202526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020256 ! SOX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008205 name: SOX21_human def: "Transcription factor SOX-21 gene" [UniProtKB:Q9Y651] synonym: "SOX25" EXACT [UniProtKB:Q9Y651] synonym: "SOXA" EXACT [UniProtKB:Q9Y651] xref: EMBL:AF107044 xref: EMBL:X65666 xref: EMBL:X71136 xref: HGNC:HGNC:11197 xref: UniGene:Hs.187577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020263 ! SOX21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008206 name: SOX2_human def: "Transcription factor SOX-2 gene" [UniProtKB:P48431] xref: EMBL:BC013923 xref: EMBL:L07335 xref: EMBL:Z31560 xref: HGNC:HGNC:11195 xref: UniGene:Hs.518438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020295 ! SOX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008207 name: SOX30_human def: "Transcription factor SOX-30 gene" [UniProtKB:O94993] xref: EMBL:AB022083 xref: EMBL:AB022441 xref: EMBL:BC033492 xref: HGNC:HGNC:30635 xref: UniGene:Hs.529462 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020266 ! SOX30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008208 name: SOX3_human def: "Transcription factor SOX-3 gene" [UniProtKB:P41225] xref: EMBL:AF264713 xref: EMBL:AL121875 xref: EMBL:BC093863 xref: EMBL:BC093865 xref: EMBL:X65665 xref: EMBL:X71135 xref: HGNC:HGNC:11199 xref: UniGene:Hs.157429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020275 ! SOX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008209 name: SOX4_human def: "Transcription factor SOX-4 gene" [UniProtKB:Q06945] xref: EMBL:AL136179 xref: EMBL:BC072668 xref: EMBL:X65661 xref: EMBL:X70683 xref: HGNC:HGNC:11200 xref: UniGene:Hs.699195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020292 ! SOX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008210 name: SUPT16H_human def: "FACT complex subunit SPT16 gene" [UniProtKB:Q9Y5B9] synonym: "FACT140" EXACT [UniProtKB:Q9Y5B9] synonym: "FACTP140" EXACT [UniProtKB:Q9Y5B9] xref: EMBL:AF152961 xref: EMBL:AF164924 xref: EMBL:BC000565 xref: EMBL:BC014046 xref: EMBL:BC064561 xref: EMBL:BC073849 xref: HGNC:HGNC:11465 xref: UniGene:Hs.213724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032537 ! SP16H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008222 name: SPTLC1_human def: "Serine palmitoyltransferase 1 gene" [UniProtKB:O15269] synonym: "LCB1" EXACT [UniProtKB:O15269] xref: EMBL:AF286703 xref: EMBL:AF286704 xref: EMBL:AF286705 xref: EMBL:AF286706 xref: EMBL:AF286707 xref: EMBL:AF286708 xref: EMBL:AF286709 xref: EMBL:AF286710 xref: EMBL:AF286711 xref: EMBL:AF286712 xref: EMBL:AF286713 xref: EMBL:AF286714 xref: EMBL:AF286715 xref: EMBL:AF286716 xref: EMBL:AF286717 xref: EMBL:AL354751 xref: EMBL:AL391219 xref: EMBL:Y08685 xref: HGNC:HGNC:11277 xref: UniGene:Hs.90458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028758 ! SPTC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008223 name: SRF_human def: "Serum response factor gene" [UniProtKB:P11831] xref: EMBL:AL133375 xref: EMBL:AL355385 xref: EMBL:BC048211 xref: EMBL:BC052572 xref: EMBL:CH471081 xref: EMBL:J03161 xref: HGNC:HGNC:11291 xref: UniGene:Hs.520140 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028347 ! SRF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008224 name: SRPK2_human def: "Serine/threonine-protein kinase SRPK2 gene" [UniProtKB:P78362] xref: EMBL:AC005070 xref: EMBL:AY354201 xref: EMBL:BC035214 xref: EMBL:BC068547 xref: EMBL:U88666 xref: HGNC:HGNC:11306 xref: UniGene:Hs.285197 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022813 ! SRPK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008226 name: SRY_human def: "Sex-determining region Y protein gene" [UniProtKB:Q05066] synonym: "TDF" EXACT [UniProtKB:Q05066] xref: EMBL:AY330303 xref: EMBL:AY998486 xref: EMBL:BC074923 xref: EMBL:BC074924 xref: EMBL:L08063 xref: EMBL:L10101 xref: EMBL:L10102 xref: EMBL:S53156 xref: EMBL:S56543 xref: EMBL:X53772 xref: EMBL:X96421 xref: HGNC:HGNC:11311 xref: UniGene:Hs.1992 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020282 ! SRY_HUMAN relationship: codes_for CCO:B0020290 ! Q7Z5C6_HUMAN relationship: codes_for CCO:B0020296 ! Q52MY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008238 name: STK38L_human def: "Serine/threonine-protein kinase 38-like gene" [UniProtKB:Q9Y2H1] synonym: "KIAA0965" EXACT [UniProtKB:Q9Y2H1] synonym: "NDR2" EXACT [UniProtKB:Q9Y2H1] xref: EMBL:AB023182 xref: EMBL:AK291055 xref: EMBL:BC028603 xref: EMBL:CH471094 xref: HGNC:HGNC:17848 xref: UniGene:Hs.184523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015573 ! ST38L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008241 name: STAT6_human def: "Signal transducer and activator of transcription 6 gene" [UniProtKB:P42226] xref: EMBL:AB103089 xref: EMBL:AF067572 xref: EMBL:AF067573 xref: EMBL:AF067575 xref: EMBL:AF417842 xref: EMBL:BC075852 xref: EMBL:U16031 xref: HGNC:HGNC:11368 xref: UniGene:Hs.524518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029685 ! STAT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008244 name: STK24_human def: "Serine/threonine-protein kinase 24 gene" [UniProtKB:Q9Y6E0] synonym: "MST3" EXACT [UniProtKB:Q9Y6E0] synonym: "STK3" EXACT [UniProtKB:Q9Y6E0] xref: EMBL:AF024636 xref: EMBL:AF083420 xref: EMBL:BC035578 xref: HGNC:HGNC:11403 xref: UniGene:Hs.508514 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022743 ! STK24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008245 name: STK25_human def: "Serine/threonine-protein kinase 25 gene" [UniProtKB:O00506] synonym: "SOK1" EXACT [UniProtKB:O00506] synonym: "YSK1" EXACT [UniProtKB:O00506] xref: EMBL:AC110299 xref: EMBL:BC007852 xref: EMBL:BC091505 xref: EMBL:BT019961 xref: EMBL:D63780 xref: EMBL:DQ093965 xref: EMBL:X99325 xref: HGNC:HGNC:11404 xref: UniGene:Hs.516807 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022748 ! STK25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008246 name: STK38_human def: "Serine/threonine-protein kinase 38 gene" [UniProtKB:Q15208] synonym: "NDR1" EXACT [UniProtKB:Q15208] xref: EMBL:BC012085 xref: EMBL:BC095413 xref: EMBL:Z35102 xref: EMBL:Z85986 xref: HGNC:HGNC:17847 xref: UniGene:Hs.409578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015584 ! STK38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008247 name: STMN2_human def: "Stathmin-2 gene" [UniProtKB:Q93045] synonym: "SCG10" EXACT [UniProtKB:Q93045] synonym: "SCGN10" EXACT [UniProtKB:Q93045] xref: EMBL:BC006302 xref: EMBL:BT020034 xref: EMBL:CR456833 xref: EMBL:D50375 xref: EMBL:S82024 xref: HGNC:HGNC:10577 xref: UniGene:Hs.521651 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023034 ! STMN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008248 name: STMN3_human def: "Stathmin-3 gene" [UniProtKB:Q9NZ72] synonym: "SCLIP" EXACT [UniProtKB:Q9NZ72] xref: EMBL:AF069709 xref: EMBL:AF217796 xref: EMBL:AL353715 xref: EMBL:BC009381 xref: EMBL:BC025234 xref: HGNC:HGNC:15926 xref: UniGene:Hs.639609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023039 ! STMN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008249 name: STMN4_human def: "Stathmin-4 gene" [UniProtKB:Q9H169] xref: EMBL:AJ303455 xref: EMBL:AL136568 xref: EMBL:BC011520 xref: EMBL:BC111001 xref: HGNC:HGNC:16078 xref: UniGene:Hs.201058 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023038 ! STMN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008253 name: SUV420H1_human def: "Histone-lysine N-methyltransferase SUV420H1 gene" [UniProtKB:Q4FZB7] synonym: "CGI-85" EXACT [UniProtKB:Q4FZB7] synonym: "KMT5B" EXACT [UniProtKB:Q4FZB7] xref: EMBL:AF151843 xref: EMBL:AF264782 xref: EMBL:AK000046 xref: EMBL:AL512763 xref: EMBL:AP002992 xref: EMBL:BC002522 xref: EMBL:BC012933 xref: EMBL:BC065287 xref: EMBL:BC087834 xref: EMBL:BC098121 xref: EMBL:BC099714 xref: EMBL:BC103498 xref: EMBL:BC104483 xref: HGNC:HGNC:24283 xref: UniGene:Hs.632120 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015494 ! SUV41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008254 name: SUV420H2_human def: "Histone-lysine N-methyltransferase SUV420H2 gene" [UniProtKB:Q86Y97] synonym: "KMT5C" EXACT [UniProtKB:Q86Y97] synonym: "PP7130" EXACT [UniProtKB:Q86Y97] xref: EMBL:AF289582 xref: EMBL:BC005842 xref: EMBL:BC019313 xref: EMBL:BC044889 xref: HGNC:HGNC:28405 xref: UniGene:Hs.590982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015493 ! SUV42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008256 name: SYNGAP1_human def: "Ras GTPase-activating protein SynGAP gene" [UniProtKB:Q96PV0] synonym: "KIAA1938" EXACT [UniProtKB:Q96PV0] xref: EMBL:AB067525 xref: EMBL:AL021366 xref: EMBL:AL662799 xref: EMBL:AL713634 xref: EMBL:BX088650 xref: HGNC:HGNC:11497 xref: UniGene:Hs.586264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019340 ! SYGP1_HUMAN relationship: codes_for CCO:B0019348 ! A2AB18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008257 name: WARS_human def: "Tryptophanyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:P23381] synonym: "IFI53" EXACT [UniProtKB:P23381] synonym: "WRS" EXACT [UniProtKB:P23381] xref: EMBL:BC017489 xref: EMBL:M61715 xref: EMBL:M77804 xref: EMBL:S82905 xref: EMBL:X59892 xref: EMBL:X62570 xref: EMBL:X67920 xref: EMBL:X67921 xref: EMBL:X67922 xref: EMBL:X67923 xref: EMBL:X67924 xref: EMBL:X67925 xref: EMBL:X67926 xref: EMBL:X67927 xref: EMBL:X67928 xref: HGNC:HGNC:12729 xref: UniGene:Hs.497599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021811 ! SYWC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008258 name: TAS2R40_human def: "Taste receptor type 2 member 40 gene" [UniProtKB:P59535] synonym: "GPR60" EXACT [UniProtKB:P59535] xref: EMBL:AF494229 xref: EMBL:AY724957 xref: EMBL:BC101795 xref: EMBL:BC101797 xref: HGNC:HGNC:18885 xref: UniGene:Hs.352241 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017773 ! T2R40_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008259 name: TAS2R5_human def: "Taste receptor type 2 member 5 gene" [UniProtKB:Q9NYW4] xref: EMBL:AC004979 xref: EMBL:AF227132 xref: EMBL:AY724966 xref: EMBL:BC069509 xref: EMBL:BC101586 xref: EMBL:BC101588 xref: HGNC:HGNC:14912 xref: UniGene:Hs.675370 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031607 ! TA2R5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008260 name: TAF12_human def: "Transcription initiation factor TFIID subunit 12 gene" [UniProtKB:Q16514] synonym: "TAF15" EXACT [UniProtKB:Q16514] synonym: "TAF2J" EXACT [UniProtKB:Q16514] synonym: "TAFII20" EXACT [UniProtKB:Q16514] xref: EMBL:AL513497 xref: EMBL:AY206865 xref: EMBL:BC011986 xref: EMBL:BT007031 xref: EMBL:D50544 xref: EMBL:U57693 xref: EMBL:X84002 xref: HGNC:HGNC:11545 xref: UniGene:Hs.530251 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018582 ! TAF12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008261 name: TAF5_human def: "Transcription initiation factor TFIID subunit 5 gene" [UniProtKB:Q15542] synonym: "TAF2D" EXACT [UniProtKB:Q15542] xref: EMBL:AK223615 xref: EMBL:AL591408 xref: EMBL:BC052268 xref: EMBL:U75309 xref: EMBL:U80191 xref: EMBL:X95525 xref: HGNC:HGNC:11539 xref: UniGene:Hs.96103 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019365 ! TAF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008262 name: TAF9B_human def: "Transcription initiation factor TFIID subunit 9B gene" [UniProtKB:Q9HBM6] synonym: "TAF9L" EXACT [UniProtKB:Q9HBM6] xref: EMBL:AF077053 xref: EMBL:AF220509 xref: EMBL:AL049589 xref: EMBL:BC009566 xref: EMBL:BC010350 xref: EMBL:BC071649 xref: HGNC:HGNC:17306 xref: UniGene:Hs.592248 xref: UniGene:Hs.643614 xref: UniGene:Hs.702057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014928 ! TAF9B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008265 name: TNKS1BP1_human def: "182 kDa tankyrase 1-binding protein gene" [UniProtKB:Q9C0C2] synonym: "KIAA1741" EXACT [UniProtKB:Q9C0C2] synonym: "TAB182" EXACT [UniProtKB:Q9C0C2] xref: EMBL:AB051528 xref: EMBL:AF441771 xref: EMBL:AK074113 xref: EMBL:AK124903 xref: EMBL:BC023622 xref: HGNC:HGNC:19081 xref: UniGene:Hs.530730 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014982 ! TB182_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008266 name: TUBA1C_human def: "TUBA1C protein gene" [UniProtKB:Q8N532] xref: EMBL:BC033064 xref: HGNC:HGNC:20768 xref: UniGene:Hs.652390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063110 ! Q8N532_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008267 name: TUBA3C_human def: "Tubulin alpha-3C/D chain gene" [UniProtKB:Q13748] synonym: "TUBA2" EXACT [UniProtKB:Q13748] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024576 ! TBA3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008268 name: TUBA3D_human def: "Tubulin alpha-3C/D chain gene" [UniProtKB:Q13748] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024576 ! TBA3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008270 name: TUBA8_human def: "Tubulin alpha-8 chain gene" [UniProtKB:Q9NY65] synonym: "TUBAL2" EXACT [UniProtKB:Q9NY65] xref: EMBL:AJ245922 xref: EMBL:BC074827 xref: EMBL:BC104845 xref: EMBL:CR456600 xref: HGNC:HGNC:12410 xref: UniGene:Hs.137400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024578 ! TBA8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008271 name: TUBB2C_human def: "Tubulin beta-2C chain gene" [UniProtKB:P68371] xref: EMBL:BC001911 xref: EMBL:BC002783 xref: EMBL:BC002885 xref: EMBL:BC004188 xref: EMBL:BC007889 xref: EMBL:BC012835 xref: EMBL:BC019359 xref: EMBL:BC019829 xref: EMBL:BC039175 xref: EMBL:BC071889 xref: EMBL:X02344 xref: HGNC:HGNC:20771 xref: UniGene:Hs.433615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019878 ! TBB2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008273 name: TUBB6_human def: "Tubulin beta-6 chain gene" [UniProtKB:Q9BUF5] xref: EMBL:AK022340 xref: EMBL:BC002654 xref: HGNC:HGNC:20776 xref: UniGene:Hs.193491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019883 ! TBB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008274 name: TBC1D13_human def: "TBC1 domain family member 13 gene" [UniProtKB:Q9NVG8] xref: EMBL:AK001605 xref: EMBL:AK289777 xref: EMBL:AL441992 xref: EMBL:BC132817 xref: EMBL:CH471090 xref: HGNC:HGNC:25571 xref: UniGene:Hs.3376 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031753 ! Q5T270_HUMAN relationship: codes_for CCO:B0031754 ! TBC13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008276 name: TBPL2_human def: "TATA box-binding protein-like protein 2 gene" [UniProtKB:Q6SJ96] synonym: "TRF3" EXACT [UniProtKB:Q6SJ96] xref: EMBL:AY457923 xref: EMBL:BC117159 xref: EMBL:BC117185 xref: EMBL:DQ448593 xref: HGNC:HGNC:19841 xref: UniGene:Hs.528278 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032975 ! TBPL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008277 name: TBX15_human def: "T-box transcription factor TBX15 gene" [UniProtKB:Q96SF7] synonym: "TBX14" EXACT [UniProtKB:Q96SF7] xref: EMBL:AK127536 xref: EMBL:AL139420 xref: EMBL:AL357045 xref: EMBL:BC122553 xref: HGNC:HGNC:11594 xref: UniGene:Hs.146196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018667 ! Q5JT54_HUMAN relationship: codes_for CCO:B0018669 ! TBX15_HUMAN relationship: codes_for CCO:B0056482 ! Q5JT55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008278 name: TBX18_human def: "T-box transcription factor TBX18 gene" [UniProtKB:O95935] xref: EMBL:AJ010278 xref: EMBL:AL035694 xref: EMBL:BC040697 xref: HGNC:HGNC:11595 xref: UniGene:Hs.251830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018662 ! Q8IW86_HUMAN relationship: codes_for CCO:B0018677 ! TBX18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008279 name: TBX22_human def: "T-box transcription factor TBX22 gene" [UniProtKB:Q9Y458] synonym: "TBOX22" EXACT [UniProtKB:Q9Y458] xref: EMBL:AF251684 xref: EMBL:AL031000 xref: EMBL:AY035371 xref: EMBL:BC014194 xref: EMBL:CH471104 xref: HGNC:HGNC:11600 xref: UniGene:Hs.374253 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018664 ! TBX22_HUMAN relationship: codes_for CCO:B0018671 ! Q5JZ06_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008280 name: CCT8_human def: "T-complex protein 1 subunit theta gene" [UniProtKB:P50990] synonym: "CCTQ" EXACT [UniProtKB:P50990] synonym: "KIAA0002" EXACT [UniProtKB:P50990] xref: EMBL:AF129075 xref: EMBL:AL163249 xref: EMBL:BC072001 xref: EMBL:BC095470 xref: EMBL:D13627 xref: EMBL:D42052 xref: EMBL:Z37163 xref: HGNC:HGNC:1623 xref: UniGene:Hs.125113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032388 ! TCPQ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008281 name: VCP_human def: "Transitional endoplasmic reticulum ATPase gene" [UniProtKB:P55072] xref: EMBL:AC004472 xref: EMBL:AF100752 xref: EMBL:Z70768 xref: HGNC:HGNC:12666 xref: UniGene:Hs.529782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021184 ! TERA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008282 name: GTF2H2_human def: "General transcription factor IIH subunit 2 gene" [UniProtKB:Q13888] synonym: "BTF2P44" EXACT [UniProtKB:Q13888] xref: EMBL:AF078847 xref: EMBL:BC005345 xref: EMBL:U21910 xref: EMBL:U21911 xref: EMBL:U80017 xref: EMBL:Z30094 xref: HGNC:HGNC:4656 xref: UniGene:Hs.191356 xref: UniGene:Hs.655216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018285 ! TF2H2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008283 name: GTF2H3_human def: "General transcription factor IIH subunit 3 gene" [UniProtKB:Q13889] xref: EMBL:AF548661 xref: EMBL:BC039726 xref: EMBL:BC047868 xref: EMBL:BC065250 xref: EMBL:Z30093 xref: HGNC:HGNC:4657 xref: UniGene:Hs.355348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023973 ! TF2H3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008284 name: TFG_human def: "Protein TFG gene" [UniProtKB:Q92734] xref: EMBL:AK093456 xref: EMBL:BC001483 xref: EMBL:BC009241 xref: EMBL:BC023599 xref: EMBL:BT007428 xref: EMBL:CH471052 xref: EMBL:CR456781 xref: EMBL:X85960 xref: EMBL:Y07968 xref: HGNC:HGNC:11758 xref: UniGene:Hs.518123 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034185 ! Q969I2_HUMAN relationship: codes_for CCO:B0034188 ! TFG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008285 name: TGFB1I1_human def: "Transforming growth factor beta-1-induced transcript 1 protein gene" [UniProtKB:O43294] synonym: "ARA55" EXACT [UniProtKB:O43294] xref: EMBL:AB007836 xref: EMBL:AF116343 xref: EMBL:BC001507 xref: EMBL:BC001830 xref: EMBL:BC017288 xref: EMBL:BC032545 xref: EMBL:DQ309025 xref: HGNC:HGNC:11767 xref: UniGene:Hs.513530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017844 ! TGFI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008286 name: TGIF2_human def: "Homeobox protein TGIF2 gene" [UniProtKB:Q9GZN2] xref: EMBL:AB042646 xref: EMBL:AK074802 xref: EMBL:AL050318 xref: EMBL:BC006549 xref: EMBL:BC012816 xref: HGNC:HGNC:15764 xref: UniGene:Hs.632264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021266 ! TGIF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008287 name: TGS1_human def: "Trimethylguanosine synthase homolog gene" [UniProtKB:Q96RS0] synonym: "HCA137" EXACT [UniProtKB:Q96RS0] synonym: "NCOA6IP" EXACT [UniProtKB:Q96RS0] synonym: "PIMT" EXACT [UniProtKB:Q96RS0] xref: EMBL:AC100817 xref: EMBL:AF286340 xref: EMBL:AF432215 xref: EMBL:AK026648 xref: EMBL:AY028423 xref: EMBL:AY534911 xref: EMBL:BC011999 xref: HGNC:HGNC:17843 xref: UniGene:Hs.335068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032700 ! TGS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008289 name: THOC4_human def: "THO complex subunit 4 gene" [UniProtKB:Q86V81] synonym: "ALY" EXACT [UniProtKB:Q86V81] synonym: "BEF" EXACT [UniProtKB:Q86V81] xref: EMBL:AF047002 xref: EMBL:BC052302 xref: HGNC:HGNC:19071 xref: UniGene:Hs.534385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017403 ! THOC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008291 name: SPOCK1_human def: "Testican-1 precursor gene" [UniProtKB:Q08629] synonym: "SPOCK" EXACT [UniProtKB:Q08629] synonym: "TIC1" EXACT [UniProtKB:Q08629] synonym: "TICN1" EXACT [UniProtKB:Q08629] xref: EMBL:AC005213 xref: EMBL:AC091818 xref: EMBL:AC106746 xref: EMBL:AC106809 xref: EMBL:AF231124 xref: EMBL:X73608 xref: HGNC:HGNC:11251 xref: UniGene:Hs.654695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026670 ! TICN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008292 name: SPOCK2_human def: "Testican-2 precursor gene" [UniProtKB:Q92563] synonym: "KIAA0275" EXACT [UniProtKB:Q92563] synonym: "TICN2" EXACT [UniProtKB:Q92563] synonym: "UNQ269/PRO306" EXACT [UniProtKB:Q92563] xref: EMBL:AJ001453 xref: EMBL:AY358921 xref: EMBL:BC023558 xref: EMBL:D87465 xref: HGNC:HGNC:13564 xref: UniGene:Hs.523009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026671 ! TICN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008294 name: RARRES3_human def: "Retinoic acid receptor responder protein 3 gene" [UniProtKB:Q9UL19] synonym: "RIG1" EXACT [UniProtKB:Q9UL19] synonym: "TIG3" EXACT [UniProtKB:Q9UL19] xref: EMBL:AB030815 xref: EMBL:AF060228 xref: EMBL:AF092922 xref: EMBL:BC009678 xref: HGNC:HGNC:9869 xref: UniGene:Hs.17466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028314 ! TIG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008296 name: ZFP36L1_human def: "Butyrate response factor 1 gene" [UniProtKB:Q07352] synonym: "BERG36" EXACT [UniProtKB:Q07352] synonym: "BRF1" EXACT [UniProtKB:Q07352] synonym: "ERF1" EXACT [UniProtKB:Q07352] synonym: "RNF162B" EXACT [UniProtKB:Q07352] synonym: "TIS11B" EXACT [UniProtKB:Q07352] xref: EMBL:BC018340 xref: EMBL:BT019468 xref: EMBL:X79066 xref: EMBL:X79067 xref: EMBL:X99404 xref: HGNC:HGNC:1107 xref: UniGene:Hs.699794 xref: UniGene:Hs.85155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026498 ! TISB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008297 name: TLR10_human def: "Toll-like receptor 10 precursor gene" [UniProtKB:Q9BXR5] synonym: "UNQ315/PRO358" EXACT [UniProtKB:Q9BXR5] xref: EMBL:AF296673 xref: EMBL:AY358300 xref: EMBL:BC089406 xref: HGNC:HGNC:15634 xref: UniGene:Hs.120551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030165 ! TLR10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008298 name: TLR1_human def: "Toll-like receptor 1 precursor gene" [UniProtKB:Q15399] synonym: "KIAA0012" EXACT [UniProtKB:Q15399] xref: EMBL:AL050262 xref: EMBL:BC109094 xref: EMBL:D13637 xref: EMBL:U88540 xref: HGNC:HGNC:11847 xref: UniGene:Hs.621817 xref: UniGene:Hs.654532 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030164 ! TLR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008299 name: TLR2_human def: "Toll-like receptor 2 precursor gene" [UniProtKB:O60603] synonym: "TIL4" EXACT [UniProtKB:O60603] xref: EMBL:AF051152 xref: EMBL:AF502291 xref: EMBL:BC033756 xref: EMBL:U88878 xref: HGNC:HGNC:11848 xref: UniGene:Hs.519033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030171 ! TLR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008300 name: TLR6_human def: "Toll-like receptor 6 precursor gene" [UniProtKB:Q9Y2C9] xref: EMBL:AB020807 xref: EMBL:BC111755 xref: HGNC:HGNC:16711 xref: UniGene:Hs.662185 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030167 ! Q2NKL3_HUMAN relationship: codes_for CCO:B0030172 ! TLR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008312 name: TMPRSS6_human def: "Transmembrane protease, serine 6 gene" [UniProtKB:Q8IU80] synonym: "UNQ354/PRO618" EXACT [UniProtKB:Q8IU80] xref: EMBL:AJ319876 xref: EMBL:AL022314 xref: EMBL:AY055383 xref: EMBL:AY055384 xref: EMBL:AY358398 xref: EMBL:BC039082 xref: EMBL:CR456446 xref: HGNC:HGNC:16517 xref: UniGene:Hs.370885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019541 ! TMPS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008314 name: TNPO2_human def: "Transportin-2 gene" [UniProtKB:O14787] xref: EMBL:AF007748 xref: EMBL:AF019039 xref: HGNC:HGNC:19998 xref: UniGene:Hs.705399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024778 ! TNPO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008315 name: TOP1MT_human def: "DNA topoisomerase I, mitochondrial precursor gene" [UniProtKB:Q969P6] xref: EMBL:AF349017 xref: EMBL:AF349018 xref: EMBL:AF349019 xref: EMBL:AF349020 xref: EMBL:AF349021 xref: EMBL:AF349022 xref: EMBL:AF349023 xref: EMBL:AF349024 xref: EMBL:AF349025 xref: EMBL:AF349026 xref: EMBL:AF349027 xref: EMBL:AF349028 xref: EMBL:AF349029 xref: EMBL:AF349030 xref: EMBL:AF349031 xref: HGNC:HGNC:29787 xref: UniGene:Hs.528574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024782 ! TOP1M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008320 name: TPI1_human def: "Triosephosphate isomerase gene" [UniProtKB:P60174] synonym: "TPI" EXACT [UniProtKB:P60174] xref: EMBL:BC007086 xref: EMBL:BC007812 xref: EMBL:BC009329 xref: EMBL:BC011611 xref: EMBL:BC015100 xref: EMBL:BC017165 xref: EMBL:BC017917 xref: EMBL:BC070129 xref: EMBL:J04603 xref: EMBL:M10036 xref: EMBL:U47924 xref: EMBL:X69723 xref: HGNC:HGNC:12009 xref: UniGene:Hs.524219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015866 ! TPIS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008322 name: TRPC1_human def: "Short transient receptor potential channel 1 gene" [UniProtKB:P48995] synonym: "TRP1" EXACT [UniProtKB:P48995] xref: EMBL:U31110 xref: EMBL:X89066 xref: EMBL:Z73903 xref: HGNC:HGNC:12333 xref: UniGene:Hs.250687 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025169 ! TRPC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008323 name: TRPC4_human def: "Short transient receptor potential channel 4 gene" [UniProtKB:Q9UBN4] xref: EMBL:AF063822 xref: EMBL:AF063823 xref: EMBL:AF063824 xref: EMBL:AF063825 xref: EMBL:AF175406 xref: EMBL:AF421358 xref: EMBL:AF421359 xref: EMBL:U40983 xref: HGNC:HGNC:12336 xref: UniGene:Hs.262960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025166 ! TRPC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008324 name: TRPC5_human def: "Short transient receptor potential channel 5 gene" [UniProtKB:Q9UL62] synonym: "TRP5" EXACT [UniProtKB:Q9UL62] xref: EMBL:AC005191 xref: EMBL:AF054568 xref: EMBL:AL049563 xref: HGNC:HGNC:12337 xref: UniGene:Hs.657709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025167 ! TRPC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008326 name: ZFP36_human def: "Tristetraproline gene" [UniProtKB:P26651] synonym: "G0S24" EXACT [UniProtKB:P26651] synonym: "RNF162A" EXACT [UniProtKB:P26651] synonym: "TIS11A" EXACT [UniProtKB:P26651] synonym: "TTP" EXACT [UniProtKB:P26651] xref: EMBL:AY771351 xref: EMBL:BC009693 xref: EMBL:M63625 xref: EMBL:M92843 xref: EMBL:M92844 xref: HGNC:HGNC:12862 xref: UniGene:Hs.534052 xref: UniGene:Hs.704733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026499 ! TTP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008329 name: ASCC3L1_human def: "U5 small nuclear ribonucleoprotein 200 kDa helicase gene" [UniProtKB:O75643] synonym: "HELIC2" EXACT [UniProtKB:O75643] synonym: "KIAA0788" EXACT [UniProtKB:O75643] xref: EMBL:AB018331 xref: EMBL:AK024391 xref: EMBL:AK090671 xref: EMBL:AY572488 xref: EMBL:BC007577 xref: EMBL:BC065924 xref: EMBL:Z70200 xref: HGNC:HGNC:30859 xref: UniGene:Hs.246112 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020984 ! U520_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008330 name: UBE2D1_human def: "Ubiquitin-conjugating enzyme E2 D1 gene" [UniProtKB:P51668] synonym: "SFT" EXACT [UniProtKB:P51668] synonym: "UBCH5" EXACT [UniProtKB:P51668] synonym: "UBCH5A" EXACT [UniProtKB:P51668] xref: EMBL:AF020761 xref: EMBL:AF257220 xref: EMBL:AJ272367 xref: EMBL:AJ293565 xref: EMBL:BC005980 xref: EMBL:BC015997 xref: EMBL:BT007041 xref: EMBL:X78140 xref: HGNC:HGNC:12474 xref: UniGene:Hs.129683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019462 ! UB2D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008332 name: UBE2D3_human def: "Ubiquitin-conjugating enzyme E2 D3 gene" [UniProtKB:P61077] synonym: "UBCH5C" EXACT [UniProtKB:P61077] xref: EMBL:AF213884 xref: EMBL:AF224669 xref: EMBL:BC003395 xref: EMBL:BC037894 xref: EMBL:BC066917 xref: EMBL:CH471057 xref: EMBL:CR456916 xref: EMBL:U39318 xref: HGNC:HGNC:12476 xref: UniGene:Hs.518773 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019461 ! UB2D3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008333 name: UBE2D4_human def: "Ubiquitin-conjugating enzyme E2 D4 gene" [UniProtKB:Q9Y2X8] xref: EMBL:AF125044 xref: EMBL:AK001446 xref: EMBL:BC004104 xref: HGNC:HGNC:21647 xref: UniGene:Hs.19196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019459 ! UB2D4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008341 name: HRSP12_human def: "Ribonuclease UK114 gene" [UniProtKB:P52758] synonym: "PSP" EXACT [UniProtKB:P52758] xref: EMBL:AY026764 xref: EMBL:BC010280 xref: EMBL:BC012592 xref: EMBL:CR541652 xref: EMBL:X95384 xref: HGNC:HGNC:16897 xref: UniGene:Hs.18426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026435 ! UK114_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008345 name: ATP6V0C_human def: "V-type proton ATPase 16 kDa proteolipid subunit gene" [UniProtKB:P27449] synonym: "ATP6C" EXACT [UniProtKB:P27449] synonym: "ATP6L" EXACT [UniProtKB:P27449] synonym: "ATPL" EXACT [UniProtKB:P27449] xref: EMBL:BC004537 xref: EMBL:BC007389 xref: EMBL:BC007759 xref: EMBL:BC009290 xref: EMBL:BT007155 xref: EMBL:M62762 xref: HGNC:HGNC:855 xref: UniGene:Hs.389107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028140 ! VATL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008352 name: WDHD1_human def: "WD repeat and HMG-box DNA-binding protein 1 gene" [UniProtKB:O75717] synonym: "AND1" EXACT [UniProtKB:O75717] xref: EMBL:AJ006266 xref: EMBL:AL160471 xref: EMBL:BC000622 xref: EMBL:BC043349 xref: EMBL:BC063041 xref: HGNC:HGNC:23170 xref: UniGene:Hs.385998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019767 ! WDHD1_HUMAN relationship: codes_for CCO:B0026837 ! A8MRA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008356 name: XAB2_human def: "Pre-mRNA-splicing factor SYF1 gene" [UniProtKB:Q9HCS7] synonym: "HCNP" EXACT [UniProtKB:Q9HCS7] synonym: "KIAA1177" EXACT [UniProtKB:Q9HCS7] synonym: "PP3898" EXACT [UniProtKB:Q9HCS7] synonym: "SYF1" EXACT [UniProtKB:Q9HCS7] xref: EMBL:AB026111 xref: EMBL:AB033003 xref: EMBL:AF226051 xref: EMBL:AF258567 xref: EMBL:AF547265 xref: EMBL:AK074035 xref: EMBL:BC007208 xref: EMBL:BC008778 xref: HGNC:HGNC:14089 xref: UniGene:Hs.9822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041548 ! SYF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008357 name: XRCC1_human def: "DNA repair protein XRCC1 gene" [UniProtKB:P18887] xref: EMBL:AC018758 xref: EMBL:AF512504 xref: EMBL:M36089 xref: HGNC:HGNC:12828 xref: UniGene:Hs.98493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020639 ! XRCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008365 name: ZFAND6_human def: "AN1-type zinc finger protein 6 gene" [UniProtKB:Q6FIF0] synonym: "AWP1" EXACT [UniProtKB:Q6FIF0] synonym: "HT032" EXACT [UniProtKB:Q6FIF0] synonym: "ZA20D3" EXACT [UniProtKB:Q6FIF0] xref: EMBL:AF061739 xref: EMBL:AF261138 xref: EMBL:AJ251095 xref: EMBL:AL136598 xref: EMBL:BC005283 xref: EMBL:CR533476 xref: HGNC:HGNC:30164 xref: UniGene:Hs.654787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021303 ! ZFAN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008371 name: ZNF667_human def: "Zinc finger protein 667 gene" [UniProtKB:Q5HYK9] xref: EMBL:AC006116 xref: EMBL:AC013256 xref: EMBL:AK024073 xref: EMBL:BC074898 xref: EMBL:BC074899 xref: EMBL:BX647401 xref: EMBL:CH471135 xref: HGNC:HGNC:28854 xref: UniGene:Hs.433473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022381 ! ZN667_HUMAN relationship: codes_for CCO:B0022382 ! Q9ULA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008372 name: ZNFX1_human def: "NFX1-type zinc finger-containing protein 1 gene" [UniProtKB:Q9P2E3] synonym: "KIAA1404" EXACT [UniProtKB:Q9P2E3] xref: EMBL:AB037825 xref: EMBL:AK000573 xref: EMBL:AK002139 xref: EMBL:AK022641 xref: EMBL:AK023836 xref: EMBL:AL049766 xref: HGNC:HGNC:29271 xref: UniGene:Hs.371794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017601 ! ZNFX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008374 name: ZNF259_human def: "Zinc finger protein ZPR1 gene" [UniProtKB:O75312] synonym: "ZPR1" EXACT [UniProtKB:O75312] xref: EMBL:AF019767 xref: EMBL:BC004256 xref: EMBL:BC012162 xref: EMBL:BC017349 xref: EMBL:BC017380 xref: EMBL:BC111028 xref: EMBL:BT006642 xref: HGNC:HGNC:13051 xref: UniGene:Hs.591942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018024 ! ZPR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008376 name: HLA-DRB1_human def: "HLA class II histocompatibility antigen, DRB1-4 beta chain precursor gene" [UniProtKB:P13760] xref: EMBL:AF029269 xref: EMBL:AF112876 xref: EMBL:AJ295845 xref: EMBL:AJ297586 xref: EMBL:AL137064 xref: EMBL:K02776 xref: EMBL:L42143 xref: EMBL:M15069 xref: EMBL:M17381 xref: EMBL:M20548 xref: EMBL:M20549 xref: EMBL:M20550 xref: EMBL:X02902 xref: EMBL:X96851 xref: HGNC:HGNC:4948 xref: UniGene:Hs.534322 xref: UniGene:Hs.696211 xref: UniGene:Hs.701691 xref: UniGene:Hs.705372 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055019 ! 2B14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008379 name: MAST2_human def: "Microtubule-associated serine/threonine-protein kinase 2 gene" [UniProtKB:Q6P0Q8] synonym: "KIAA0807" EXACT [UniProtKB:Q6P0Q8] synonym: "MAST205" EXACT [UniProtKB:Q6P0Q8] xref: EMBL:AB018350 xref: EMBL:AB047005 xref: EMBL:AL358075 xref: EMBL:AL603882 xref: EMBL:AL603888 xref: EMBL:AL645480 xref: EMBL:AL833919 xref: EMBL:BC015816 xref: EMBL:BC065499 xref: HGNC:HGNC:19035 xref: UniGene:Hs.319481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056876 ! MAST2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008391 name: BCR/ABL fusion_human def: "BCR/ABL fusion protein isoform X8 gene" [UniProtKB:A9UF01] xref: EMBL:AF487522 xref: EMBL:EU216065 xref: EMBL:EU216066 xref: EMBL:EU216069 xref: EMBL:EU216071 xref: HGNC:HGNC:1014 xref: UniGene:Hs.517461 xref: UniGene:Hs.634378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034172 ! A9UF07_HUMAN relationship: codes_for CCO:B0034175 ! A9UF02_HUMAN relationship: codes_for CCO:B0054152 ! A9UF01_HUMAN relationship: codes_for CCO:B0054153 ! A9UF05_HUMAN relationship: codes_for CCO:B0057923 ! Q8TDA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008392 name: C20orf95_human def: "Rho GTPase-activating protein 18-like gene" [UniProtKB:Q5TG30] xref: EMBL:AL035419 xref: HGNC:HGNC:16226 xref: UniGene:Hs.451997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056619 ! RG18L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008396 name: MICA_human def: "MHC class I polypeptide-related sequence A precursor gene" [UniProtKB:Q29983] synonym: "PERB11.1" EXACT [UniProtKB:Q29983] xref: EMBL:AB015600 xref: EMBL:AF011829 xref: EMBL:AF011830 xref: EMBL:AF011831 xref: EMBL:AF011832 xref: EMBL:AF011833 xref: EMBL:AF011834 xref: EMBL:AF011835 xref: EMBL:AF011836 xref: EMBL:AF011837 xref: EMBL:AF011838 xref: EMBL:AF011839 xref: EMBL:AF011840 xref: EMBL:AF011841 xref: EMBL:AF011842 xref: EMBL:AF011843 xref: EMBL:AF011844 xref: EMBL:AF011845 xref: EMBL:AF011846 xref: EMBL:AF011847 xref: EMBL:AF011848 xref: EMBL:AF011849 xref: EMBL:AF011850 xref: EMBL:AF011851 xref: EMBL:AF011852 xref: EMBL:AF011853 xref: EMBL:AF011854 xref: EMBL:AF011855 xref: EMBL:AF011856 xref: EMBL:AF011857 xref: EMBL:AF011858 xref: EMBL:AF011859 xref: EMBL:AF011860 xref: EMBL:AF011861 xref: EMBL:AF011862 xref: EMBL:AF011863 xref: EMBL:AF011864 xref: EMBL:AF011865 xref: EMBL:AF011866 xref: EMBL:AF011867 xref: EMBL:AF011868 xref: EMBL:AF011869 xref: EMBL:AF011870 xref: EMBL:AF011871 xref: EMBL:AF011872 xref: EMBL:AF011873 xref: EMBL:AF011874 xref: EMBL:AF011875 xref: EMBL:AF011876 xref: EMBL:AF011877 xref: EMBL:AF011878 xref: EMBL:AF011879 xref: EMBL:AF011880 xref: EMBL:AF011881 xref: EMBL:AF011882 xref: EMBL:AF011883 xref: EMBL:AF011884 xref: EMBL:AF011885 xref: EMBL:AF011886 xref: EMBL:AF011887 xref: EMBL:AF011888 xref: EMBL:AF079413 xref: EMBL:AF079414 xref: EMBL:AF079415 xref: EMBL:AF079416 xref: EMBL:AF079417 xref: EMBL:AF079418 xref: EMBL:AF079419 xref: EMBL:AF079420 xref: EMBL:AF079421 xref: EMBL:AF079422 xref: EMBL:AF079423 xref: EMBL:AF079424 xref: EMBL:AF079425 xref: EMBL:AF079426 xref: EMBL:AF079427 xref: EMBL:AF085011 xref: EMBL:AF085012 xref: EMBL:AF085013 xref: EMBL:AF085014 xref: EMBL:AF085015 xref: EMBL:AF085016 xref: EMBL:AF085017 xref: EMBL:AF085018 xref: EMBL:AF085019 xref: EMBL:AF085020 xref: EMBL:AF085021 xref: EMBL:AF085022 xref: EMBL:AF085023 xref: EMBL:AF085024 xref: EMBL:AF085025 xref: EMBL:AF085026 xref: EMBL:AF085027 xref: EMBL:AF085028 xref: EMBL:AF085029 xref: EMBL:AF085030 xref: EMBL:AF085031 xref: EMBL:AF085032 xref: EMBL:AF085033 xref: EMBL:AF085034 xref: EMBL:AF085035 xref: EMBL:AF085036 xref: EMBL:AF085037 xref: EMBL:AF085038 xref: EMBL:AF085039 xref: EMBL:AF085040 xref: EMBL:AF085041 xref: EMBL:AF085042 xref: EMBL:AF085043 xref: EMBL:AF085044 xref: EMBL:AF085045 xref: EMBL:AF085046 xref: EMBL:AF085047 xref: EMBL:AF085048 xref: EMBL:AF085049 xref: EMBL:AF085050 xref: EMBL:AF085051 xref: EMBL:AF085052 xref: EMBL:AF085053 xref: EMBL:AF085054 xref: EMBL:AF085055 xref: EMBL:AF085056 xref: EMBL:AF085057 xref: EMBL:AF085058 xref: EMBL:AF085059 xref: EMBL:AF085060 xref: EMBL:AF085061 xref: EMBL:AF085062 xref: EMBL:AF093113 xref: EMBL:AF093114 xref: EMBL:AF093115 xref: EMBL:AF093116 xref: EMBL:AF097403 xref: EMBL:AF097404 xref: EMBL:AF097405 xref: EMBL:AF097406 xref: EMBL:AF106632 xref: EMBL:AF106633 xref: EMBL:AF106634 xref: EMBL:AF106635 xref: EMBL:AF106636 xref: EMBL:AF106637 xref: EMBL:AF106638 xref: EMBL:AF106639 xref: EMBL:AF106640 xref: EMBL:AF106641 xref: EMBL:AF106642 xref: EMBL:AF106643 xref: EMBL:AF106644 xref: EMBL:AF106645 xref: EMBL:AF106646 xref: EMBL:AF106647 xref: EMBL:AF106648 xref: EMBL:AF106649 xref: EMBL:AF106650 xref: EMBL:AF106651 xref: EMBL:AF106652 xref: EMBL:AF106653 xref: EMBL:AF106654 xref: EMBL:AF106655 xref: EMBL:AF264735 xref: EMBL:AF264736 xref: EMBL:AF264737 xref: EMBL:AF264738 xref: EMBL:AF264739 xref: EMBL:AF264740 xref: EMBL:AF264741 xref: EMBL:AF264742 xref: EMBL:AF264743 xref: EMBL:AF264744 xref: EMBL:AF264746 xref: EMBL:AF264747 xref: EMBL:AF336063 xref: EMBL:AF336064 xref: EMBL:AF336065 xref: EMBL:AF336066 xref: EMBL:AF336067 xref: EMBL:AF336069 xref: EMBL:AF336070 xref: EMBL:AF336071 xref: EMBL:AF336072 xref: EMBL:AF336073 xref: EMBL:AF336074 xref: EMBL:AF336075 xref: EMBL:AF336076 xref: EMBL:AF336077 xref: EMBL:AF336078 xref: EMBL:AF336079 xref: EMBL:AF336080 xref: EMBL:AF336081 xref: EMBL:AF336082 xref: EMBL:AF336083 xref: EMBL:AF336084 xref: EMBL:AF336085 xref: EMBL:AF336086 xref: EMBL:AJ249394 xref: EMBL:AJ250499 xref: EMBL:AJ250500 xref: EMBL:AJ250501 xref: EMBL:AJ250502 xref: EMBL:AJ250503 xref: EMBL:AJ250504 xref: EMBL:AJ250505 xref: EMBL:AJ250506 xref: EMBL:AJ250507 xref: EMBL:AJ250802 xref: EMBL:AJ250803 xref: EMBL:AJ250804 xref: EMBL:AJ250805 xref: EMBL:AJ250990 xref: EMBL:AJ250991 xref: EMBL:AJ271789 xref: EMBL:AJ295250 xref: EMBL:AJ295251 xref: EMBL:AJ563426 xref: EMBL:AJ580805 xref: EMBL:AJ580806 xref: EMBL:AL845443 xref: EMBL:AM899996 xref: EMBL:AM944063 xref: EMBL:AY029762 xref: EMBL:AY029763 xref: EMBL:AY095537 xref: EMBL:AY603357 xref: EMBL:AY748458 xref: EMBL:AY748459 xref: EMBL:AY748460 xref: EMBL:AY748461 xref: EMBL:BC016929 xref: EMBL:CR847852 xref: EMBL:EU254723 xref: EMBL:EU267602 xref: EMBL:L14848 xref: EMBL:L29406 xref: EMBL:L29408 xref: EMBL:L29409 xref: EMBL:L29411 xref: EMBL:U56940 xref: EMBL:U56941 xref: EMBL:U56942 xref: EMBL:U56943 xref: EMBL:U56944 xref: EMBL:U56945 xref: EMBL:U56946 xref: EMBL:U56947 xref: EMBL:U56948 xref: EMBL:U56949 xref: EMBL:U56950 xref: EMBL:U56951 xref: EMBL:U56952 xref: EMBL:U56953 xref: EMBL:U56954 xref: EMBL:U56955 xref: EMBL:X92841 xref: EMBL:Y16801 xref: EMBL:Y16802 xref: EMBL:Y16803 xref: EMBL:Y16804 xref: EMBL:Y16805 xref: EMBL:Y16806 xref: EMBL:Y16807 xref: EMBL:Y16808 xref: EMBL:Y16809 xref: EMBL:Y16810 xref: EMBL:Y16811 xref: EMBL:Y18110 xref: EMBL:Y18111 xref: EMBL:Y18112 xref: HGNC:HGNC:7090 xref: UniGene:Hs.549053 xref: UniGene:Hs.77961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056200 ! MICA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008403 name: BCR-ABL1_human def: "Bcr-abl1 e6a2 chimeric protein gene" [UniProtKB:A2RQD6] xref: EMBL:AM491362 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037522 ! A2RQD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008407 name: CSE1L-2_human def: "Cellular apoptosis susceptibility protein variant 2 gene" [UniProtKB:A3RLL6] xref: EMBL:EF426455 xref: UniGene:Hs.90073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020040 ! A3RLL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008417 name: TAF6_human def: "Transcription initiation factor TFIID subunit 6 gene" [UniProtKB:P49848] synonym: "TAF2E" EXACT [UniProtKB:P49848] synonym: "TAFII70" EXACT [UniProtKB:P49848] xref: EMBL:AY149894 xref: EMBL:BC018115 xref: EMBL:CH236956 xref: EMBL:L25444 xref: EMBL:U31659 xref: HGNC:HGNC:11540 xref: UniGene:Hs.489309 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023496 ! A4D2B3_HUMAN relationship: codes_for CCO:B0053756 ! A4D299_HUMAN relationship: codes_for CCO:B0055440 ! TAF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008430 name: SORBS2_human def: "Sorbin and SH3 domain-containing protein 2 gene" [UniProtKB:O94875] synonym: "ARGBP2" EXACT [UniProtKB:O94875] synonym: "KIAA0777" EXACT [UniProtKB:O94875] xref: EMBL:AB018320 xref: EMBL:AC093797 xref: EMBL:AF049884 xref: EMBL:AF049885 xref: EMBL:BC011883 xref: EMBL:CH471056 xref: HGNC:HGNC:24098 xref: UniGene:Hs.655143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063156 ! SRBS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008434 name: OR7E91P_human def: "OR7E91P protein gene" [UniProtKB:Q8NEI9] xref: EMBL:BC030991 xref: HGNC:HGNC:14747 xref: UniGene:Hs.327033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022838 ! Q8NEI9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008435 name: CTGLF2_human def: "Centaurin-gamma-like family member 2 gene" [UniProtKB:A6NIR3] xref: EMBL:AC073389 xref: HGNC:HGNC:23467 xref: UniGene:Hs.651147 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033970 ! CTLF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008436 name: WTIP_human def: "Wilms tumor protein 1-interacting protein gene" [UniProtKB:A6NIX2] xref: EMBL:AC008747 xref: HGNC:HGNC:20964 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041576 ! WTIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008441 name: LTK_human def: "Leukocyte tyrosine kinase receptor precursor gene" [UniProtKB:P29376] synonym: "TYK1" EXACT [UniProtKB:P29376] xref: EMBL:D16105 xref: EMBL:X52213 xref: EMBL:X60702 xref: HGNC:HGNC:6721 xref: UniGene:Hs.434481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055214 ! LTK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008442 name: ANKRD30A_human def: "Ankyrin repeat domain-containing protein 30A gene" [UniProtKB:Q9BXX3] xref: EMBL:AC067744 xref: EMBL:AF269087 xref: EMBL:AL157387 xref: EMBL:AL357148 xref: HGNC:HGNC:17234 xref: UniGene:Hs.373787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058564 ! AN30A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008447 name: TSHZ2_human def: "Teashirt homolog 2 gene" [UniProtKB:Q9NRE2] synonym: "C20orf17" EXACT [UniProtKB:Q9NRE2] synonym: "TSH2" EXACT [UniProtKB:Q9NRE2] synonym: "ZNF218" EXACT [UniProtKB:Q9NRE2] xref: EMBL:AF230201 xref: EMBL:AK091206 xref: EMBL:AL121902 xref: EMBL:AL354993 xref: EMBL:BX276189 xref: EMBL:BX640770 xref: HGNC:HGNC:13010 xref: UniGene:Hs.271605 xref: UniGene:Hs.473117 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054253 ! B1AMR1_HUMAN relationship: codes_for CCO:B0058898 ! TSH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008453 name: SIR2_human def: "Silent information regulator 2 gene" [UniProtKB:A7VJH3] xref: EMBL:AB009274 xref: UniGene:Hs.466693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017935 ! A7VJH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008464 name: TREX1_human def: "Three prime repair exonuclease 1 gene" [UniProtKB:Q9NSU2] xref: EMBL:AF151105 xref: EMBL:AF319566 xref: EMBL:AF319567 xref: EMBL:AF319568 xref: EMBL:AF319569 xref: EMBL:AF483777 xref: EMBL:AJ243797 xref: EMBL:AL137745 xref: EMBL:BC023630 xref: HGNC:HGNC:12269 xref: UniGene:Hs.694840 xref: UniGene:Hs.701546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058923 ! TREX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008470 name: DLG2_human def: "Disks large homolog 2 gene" [UniProtKB:Q15700] xref: EMBL:AB209252 xref: EMBL:AC023118 xref: EMBL:AK126776 xref: EMBL:AP000852 xref: EMBL:AP001791 xref: EMBL:AP001825 xref: EMBL:AP001984 xref: EMBL:AP002370 xref: EMBL:AP002751 xref: EMBL:AP002797 xref: EMBL:AP003026 xref: EMBL:AP003305 xref: EMBL:CR749820 xref: EMBL:U32376 xref: HGNC:HGNC:2901 xref: UniGene:Hs.654862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023320 ! DLG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008491 name: MLL5_human def: "Histone-lysine N-methyltransferase MLL5 gene" [UniProtKB:Q8IZD2] synonym: "KMT2E" EXACT [UniProtKB:Q8IZD2] xref: EMBL:AC005070 xref: EMBL:AF519459 xref: EMBL:AK000940 xref: EMBL:AY147037 xref: EMBL:AY157990 xref: EMBL:AY195568 xref: EMBL:AY195569 xref: EMBL:AY222296 xref: EMBL:AY234382 xref: EMBL:AY438698 xref: EMBL:BC001296 xref: EMBL:BC040004 xref: EMBL:BC053906 xref: EMBL:BC062583 xref: EMBL:BC142987 xref: EMBL:CH471070 xref: HGNC:HGNC:18541 xref: UniGene:Hs.592262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043832 ! MLL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008493 name: SOX26_human def: "SOX-26 protein gene" [UniProtKB:O95130] xref: EMBL:AF032450 xref: HGNC:HGNC:11196 xref: UniGene:Hs.95582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020286 ! O95130_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008494 name: SOX27_human def: "SOX-27 protein gene" [UniProtKB:O95131] xref: EMBL:AF032452 xref: HGNC:HGNC:11196 xref: UniGene:Hs.95582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020258 ! O95131_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008495 name: SOX28_human def: "SOX-28 protein gene" [UniProtKB:O95132] xref: EMBL:AF032453 xref: HGNC:HGNC:11193 xref: UniGene:Hs.248184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020291 ! O95132_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008508 name: LOC729862_human def: "LOC729862 protein gene" [UniProtKB:Q0VAF8] xref: EMBL:BC121074 xref: UniGene:Hs.646006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016638 ! Q0VAF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008520 name: MSSP-2_human def: "MSSP-2 protein gene" [UniProtKB:Q14869] xref: EMBL:X77494 xref: HGNC:HGNC:9907 xref: UniGene:Hs.470412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0034177 ! Q14869_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008524 name: PML-RAR_human def: "PML-RAR protein gene" [UniProtKB:Q15156] xref: EMBL:M73779 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024847 ! Q15156_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008530 name: OR7E18P_human def: "Putative olfactory receptor gene" [UniProtKB:Q15618] synonym: "tpcr26" EXACT [UniProtKB:Q15618] xref: EMBL:X89673 xref: HGNC:HGNC:8389 xref: UniGene:Hs.381327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022863 ! Q15618_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008533 name: integrin beta 3_human def: "Integrin beta 3 gene" [UniProtKB:Q16157] xref: EMBL:S70348 xref: HGNC:HGNC:6156 xref: UniGene:Hs.218040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033110 ! Q16157_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008576 name: SLC9A3R2 variant protein_human def: "SLC9A3R2 variant protein gene" [UniProtKB:Q4LE71] xref: EMBL:AB210000 xref: HGNC:HGNC:12363 xref: UniGene:Hs.90303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022152 ! Q4LE71_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008587 name: CENTG2_human def: "Centaurin-gamma-2 gene" [UniProtKB:Q9UPQ3] synonym: "AGAP1" EXACT [UniProtKB:Q9UPQ3] synonym: "KIAA1099" EXACT [UniProtKB:Q9UPQ3] xref: EMBL:AB029022 xref: EMBL:AC012305 xref: EMBL:AC019047 xref: EMBL:AC064874 xref: EMBL:AC073989 xref: EMBL:AC079400 xref: EMBL:AF413078 xref: EMBL:AK001722 xref: EMBL:AY033765 xref: EMBL:BC060814 xref: HGNC:HGNC:16922 xref: UniGene:Hs.435039 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059263 ! CENG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008606 name: STAT6B_human def: "STAT6B gene" [UniProtKB:Q56TK0] xref: EMBL:AY615283 xref: HGNC:HGNC:11368 xref: UniGene:Hs.524518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029683 ! Q56TK0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008651 name: RABGAP1L_human def: "RAB GTPase-activating protein 1-like gene" [UniProtKB:Q5R372] synonym: "HHL" EXACT [UniProtKB:Q5R372] synonym: "KIAA0471" EXACT [UniProtKB:Q5R372] xref: EMBL:AB007940 xref: EMBL:AB019489 xref: EMBL:AB019491 xref: EMBL:AB019492 xref: EMBL:AB019493 xref: EMBL:AK095838 xref: EMBL:AL021069 xref: EMBL:AL022171 xref: EMBL:AL022400 xref: EMBL:AL031286 xref: EMBL:AL049702 xref: EMBL:AL136377 xref: EMBL:AL157958 xref: EMBL:AL161671 xref: EMBL:AL591108 xref: EMBL:AY364260 xref: EMBL:BC012094 xref: EMBL:BC018630 xref: EMBL:BC041888 xref: EMBL:CH471067 xref: EMBL:Z99127 xref: HGNC:HGNC:24663 xref: UniGene:Hs.585378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033512 ! RBG1L_HUMAN relationship: codes_for CCO:B0033513 ! Q5JZA9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008665 name: CRABP2_human def: "Cellular retinoic acid-binding protein 2 gene" [UniProtKB:P29373] xref: EMBL:AL590666 xref: EMBL:BC001109 xref: EMBL:BT019827 xref: EMBL:CR450357 xref: EMBL:M68867 xref: EMBL:M97814 xref: EMBL:M97815 xref: HGNC:HGNC:2339 xref: UniGene:Hs.405662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055212 ! RABP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008671 name: CENTB5_human def: "Centaurin-beta-5 gene" [UniProtKB:Q96P50] synonym: "KIAA1716" EXACT [UniProtKB:Q96P50] xref: EMBL:AB051503 xref: EMBL:AF411981 xref: EMBL:AL139287 xref: EMBL:AL162741 xref: EMBL:BC004874 xref: EMBL:CH471183 xref: HGNC:HGNC:16754 xref: UniGene:Hs.535257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033902 ! Q5TA42_HUMAN relationship: codes_for CCO:B0054252 ! B1AMF5_HUMAN relationship: codes_for CCO:B0058318 ! CENB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008676 name: HNF4A_human def: "Hepatocyte nuclear factor 4-alpha gene" [UniProtKB:P41235] synonym: "HNF4" EXACT [UniProtKB:P41235] synonym: "NR2A1" EXACT [UniProtKB:P41235] synonym: "TCF14" EXACT [UniProtKB:P41235] xref: EMBL:AL132772 xref: EMBL:AY680696 xref: EMBL:AY680697 xref: EMBL:AY680698 xref: EMBL:U72959 xref: EMBL:U72961 xref: EMBL:U72962 xref: EMBL:U72963 xref: EMBL:U72964 xref: EMBL:U72965 xref: EMBL:U72966 xref: EMBL:U72967 xref: EMBL:U72968 xref: EMBL:U72969 xref: EMBL:X76930 xref: EMBL:X87870 xref: EMBL:X87871 xref: EMBL:X87872 xref: EMBL:Z49825 xref: HGNC:HGNC:5024 xref: UniGene:Hs.116462 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036934 ! HNF4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008684 name: HIVEP1_human def: "Zinc finger protein 40 gene" [UniProtKB:P15822] synonym: "ZNF40" EXACT [UniProtKB:P15822] xref: EMBL:AL137221 xref: EMBL:AL157373 xref: EMBL:AL391828 xref: EMBL:M32019 xref: EMBL:X51435 xref: EMBL:Z98050 xref: HGNC:HGNC:4920 xref: UniGene:Hs.567284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055042 ! ZEP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008688 name: RESDA1_human def: "Anchor protein gene" [UniProtKB:Q5Y190] xref: EMBL:AY714129 xref: UniGene:Hs.631925 xref: UniGene:Hs.663208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032345 ! Q5Y190_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008693 name: DKFZp761C0417_human def: "Putative uncharacterized protein DKFZp761C0417 gene" [UniProtKB:Q658K5] xref: EMBL:AL834159 xref: HGNC:HGNC:9864 xref: UniGene:Hs.654583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024850 ! Q658K5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008743 name: DREG_human def: "Developmentally regulated G-protein-coupled receptor beta 2 gene" [UniProtKB:Q6F3F5] xref: EMBL:AB183546 xref: EMBL:AB183547 xref: EMBL:AB183549 xref: HGNC:HGNC:13841 xref: UniGene:Hs.318894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033403 ! Q6F3F5_HUMAN relationship: codes_for CCO:B0033411 ! Q6F3F8_HUMAN relationship: codes_for CCO:B0033419 ! Q6F3F7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008745 name: BAF53A_human def: "BAF53A protein gene" [UniProtKB:Q6FI97] xref: EMBL:CR533529 xref: HGNC:HGNC:24124 xref: UniGene:Hs.435326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016783 ! Q6FI97_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008750 name: DOC-1R_human def: "DOC-1R protein gene" [UniProtKB:Q6IAV4] synonym: "CDK2AP2" EXACT [UniProtKB:Q6IAV4] synonym: "hCG_21052" EXACT [UniProtKB:Q6IAV4] xref: EMBL:AK001498 xref: EMBL:CH471076 xref: EMBL:CR457050 xref: EMBL:CR542042 xref: HGNC:HGNC:30833 xref: UniGene:Hs.523835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030691 ! Q6IAV4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008790 name: EZR_human def: "Ezrin gene" [UniProtKB:P15311] synonym: "VIL2" EXACT [UniProtKB:P15311] xref: EMBL:AL162086 xref: EMBL:AL589931 xref: EMBL:BC013903 xref: EMBL:J05021 xref: EMBL:X51521 xref: HGNC:HGNC:12691 xref: UniGene:Hs.487027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018212 ! EZRI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008797 name: NOTCH4_human def: "Neurogenic locus notch homolog protein 4 precursor gene" [UniProtKB:Q99466] synonym: "INT3" EXACT [UniProtKB:Q99466] xref: EMBL:AB023961 xref: EMBL:AB024520 xref: EMBL:AB024578 xref: EMBL:AL662830 xref: EMBL:AL845464 xref: EMBL:AL845509 xref: EMBL:BX927239 xref: EMBL:CR933878 xref: EMBL:D63395 xref: EMBL:D86566 xref: EMBL:U89335 xref: EMBL:U95299 xref: HGNC:HGNC:7884 xref: UniGene:Hs.436100 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054185 ! B0S882_HUMAN relationship: codes_for CCO:B0054191 ! B0V1X5_HUMAN relationship: codes_for CCO:B0056532 ! Q5SPL1_HUMAN relationship: codes_for CCO:B0056538 ! Q5STG5_HUMAN relationship: codes_for CCO:B0058414 ! NOTC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008799 name: IGHM_human def: "Ig mu chain C region gene" [UniProtKB:P01871] xref: EMBL:K01310 xref: EMBL:X14939 xref: EMBL:X14940 xref: EMBL:X17115 xref: EMBL:X57086 xref: HGNC:HGNC:5541 xref: UniGene:Hs.510635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049019 ! IGHM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008803 name: UNQ6114_human def: "EPA6 gene" [UniProtKB:Q6UWM0] xref: EMBL:AY358738 xref: HGNC:HGNC:19296 xref: UniGene:Hs.653244 xref: UniGene:Hs.653853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014947 ! Q6UWM0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008805 name: HDAC7_human def: "Histone deacetylase 7 gene" [UniProtKB:Q8WUI4] synonym: "HDAC7A" EXACT [UniProtKB:Q8WUI4] xref: EMBL:AC004466 xref: EMBL:AF239243 xref: EMBL:AK001032 xref: EMBL:AK001190 xref: EMBL:AK024469 xref: EMBL:AK027781 xref: EMBL:AK122588 xref: EMBL:AK299292 xref: EMBL:AL117455 xref: EMBL:AY302468 xref: EMBL:AY321367 xref: EMBL:BC006453 xref: EMBL:BC020505 xref: EMBL:BC064840 xref: EMBL:CH471111 xref: HGNC:HGNC:14067 xref: UniGene:Hs.200063 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002002 ! HDAC7_HUMAN relationship: codes_for CCO:B0019407 ! Q6W9G7_HUMAN relationship: codes_for CCO:B0019411 ! Q6P1W9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008808 name: FLJ00357_human def: "FLJ00357 protein gene" [UniProtKB:Q6ZMJ9] xref: EMBL:AK160383 xref: HGNC:HGNC:16925 xref: UniGene:Hs.503165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024599 ! Q6ZMJ9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008823 name: hCG_2042771_human def: "Tubulin, beta, 4 gene" [UniProtKB:Q7KZS6] xref: EMBL:BT006971 xref: EMBL:CH471184 xref: HGNC:HGNC:20772 xref: UniGene:Hs.511743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019877 ! Q7KZS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008824 name: DKFZp686G05200_human def: "Putative uncharacterized protein DKFZp686G05200 gene" [UniProtKB:Q7Z324] xref: EMBL:BX538185 xref: HGNC:HGNC:581 xref: UniGene:Hs.372840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025035 ! Q7Z324_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008840 name: HNF4G_human def: "Hepatocyte nuclear factor 4-gamma gene" [UniProtKB:Q14541] synonym: "NR2A2" EXACT [UniProtKB:Q14541] xref: EMBL:AF133496 xref: EMBL:AF133497 xref: EMBL:AF133498 xref: EMBL:AF133499 xref: EMBL:AF133500 xref: EMBL:AF133501 xref: EMBL:AF133502 xref: EMBL:AF133503 xref: EMBL:AF133504 xref: EMBL:AF207953 xref: EMBL:BC054009 xref: EMBL:CR542091 xref: EMBL:Z49826 xref: HGNC:HGNC:5026 xref: UniGene:Hs.241529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024877 ! Q7Z5U9_HUMAN relationship: codes_for CCO:B0036936 ! Q6FGL6_HUMAN relationship: codes_for CCO:B0036939 ! HNF4G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008862 name: MST051_human def: "MSTP051 gene" [UniProtKB:Q8IXA8] xref: EMBL:AF115514 xref: HGNC:HGNC:13587 xref: UniGene:Hs.76917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032440 ! Q8IXA8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008865 name: GSPT2_human def: "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B gene" [UniProtKB:Q8IYD1] synonym: "ERF3B" EXACT [UniProtKB:Q8IYD1] xref: EMBL:AJ251548 xref: EMBL:AK001303 xref: EMBL:AK023155 xref: EMBL:AL929101 xref: EMBL:BC036077 xref: EMBL:CH471230 xref: HGNC:HGNC:4622 xref: UniGene:Hs.59523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041261 ! ERF3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008879 name: FLJ00380_human def: "FLJ00380 protein gene" [UniProtKB:Q8NF22] xref: EMBL:AK090459 xref: HGNC:HGNC:7781 xref: UniGene:Hs.514284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032381 ! Q8NF22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008884 name: OR7E86P_human def: "Seven transmembrane helix receptor gene" [UniProtKB:Q8NG89] xref: EMBL:AB065942 xref: HGNC:HGNC:14694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022866 ! Q8NG89_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008885 name: OR7E85P_human def: "Seven transmembrane helix receptor gene" [UniProtKB:Q8NHB9] xref: EMBL:AB065455 xref: HGNC:HGNC:14692 xref: UniGene:Hs.503150 xref: UniGene:Hs.535167 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022857 ! Q8NHB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008886 name: hCG_2002310_human def: "Seven transmembrane helix receptor (HCG2002310) gene" [UniProtKB:Q8NHC1] xref: EMBL:AB065449 xref: EMBL:CH471290 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022854 ! Q8NHC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008894 name: FLJ00186_human def: "FLJ00186 protein gene" [UniProtKB:Q8TEK8] xref: EMBL:AK074115 xref: HGNC:HGNC:17609 xref: UniGene:Hs.497579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016370 ! Q8TEK8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008895 name: KIAA1975_human def: "Centaurin-gamma-like protein KIAA1975 gene" [UniProtKB:Q8TF27] xref: EMBL:AB075855 xref: EMBL:AL136982 xref: UniGene:Hs.511787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057961 ! CTLFX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008897 name: CHTF18_human def: "Chromosome transmission fidelity protein 18 homolog gene" [UniProtKB:Q8WVB6] synonym: "CTF18" EXACT [UniProtKB:Q8WVB6] xref: EMBL:AK024476 xref: EMBL:AL031033 xref: EMBL:BC006278 xref: EMBL:BC006437 xref: EMBL:BC018184 xref: EMBL:CH471112 xref: HGNC:HGNC:18435 xref: UniGene:Hs.153850 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043835 ! CTF18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008899 name: PJCG2_human def: "Olfactory-like receptor PJCG2 gene" [UniProtKB:Q8WZ85] xref: EMBL:AF238487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022844 ! Q8WZ85_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008904 name: ACTR3B_human def: "Actin-related protein 3B gene" [UniProtKB:Q9P1U1] synonym: "ARP11" EXACT [UniProtKB:Q9P1U1] synonym: "ARP4" EXACT [UniProtKB:Q9P1U1] xref: EMBL:AC092180 xref: EMBL:AF023453 xref: EMBL:AF086920 xref: EMBL:AK294292 xref: EMBL:AK315534 xref: EMBL:BC008682 xref: EMBL:BC015207 xref: HGNC:HGNC:17256 xref: UniGene:Hs.647117 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021495 ! Q96BT2_HUMAN relationship: codes_for CCO:B0049611 ! ARP3B_HUMAN relationship: codes_for CCO:B0054026 ! A8MTG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008947 name: FKSG42_human def: "FKSG42 gene" [UniProtKB:Q9BZ74] xref: EMBL:AF334184 xref: HGNC:HGNC:24689 xref: UniGene:Hs.650500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023936 ! Q9BZ74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008948 name: TPD52L2_human def: "Tumor protein D52-like 2 gene" [UniProtKB:Q9C054] synonym: "RP1-167O5.1-004" EXACT [UniProtKB:Q9C054] synonym: "TPD52L1" EXACT [UniProtKB:Q9C054] xref: EMBL:AF208012 xref: EMBL:AK291866 xref: EMBL:AL121938 xref: EMBL:AL136128 xref: HGNC:HGNC:12006 xref: UniGene:Hs.591347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021316 ! Q9C054_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008976 name: FLJ00006_human def: "FLJ00006 protein gene" [UniProtKB:Q9NXX9] xref: EMBL:AK000006 xref: HGNC:HGNC:25228 xref: UniGene:Hs.474914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020567 ! Q9NXX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008979 name: OR7E35P_human def: "Putative taste receptor HTR2 gene" [UniProtKB:Q9P1R1] xref: EMBL:AF073924 xref: HGNC:HGNC:8408 xref: UniGene:Hs.404129 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022848 ! Q9P1R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008996 name: HER-2_human def: "Herstatin gene" [UniProtKB:Q9UK79] synonym: "ERBB2" EXACT [UniProtKB:Q9UK79] synonym: "hCG_28177" EXACT [UniProtKB:Q9UK79] xref: EMBL:AF177761 xref: EMBL:CH471152 xref: HGNC:HGNC:3430 xref: UniGene:Hs.446352 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018717 ! Q9UK79_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0008999 name: POLE1_human def: "DNA polymerase gene" [UniProtKB:Q9Y5S5] xref: EMBL:AF127937 xref: EMBL:AF127939 xref: EMBL:AF127940 xref: EMBL:AF127941 xref: EMBL:AF127942 xref: EMBL:AF127943 xref: EMBL:AF127944 xref: EMBL:AF127945 xref: EMBL:AF127946 xref: EMBL:AF127947 xref: EMBL:AF127948 xref: EMBL:AF127949 xref: EMBL:AF127950 xref: EMBL:AF127951 xref: EMBL:AF127952 xref: EMBL:AF127953 xref: EMBL:AF127954 xref: EMBL:AF127955 xref: EMBL:AF127956 xref: EMBL:AF127957 xref: EMBL:AF127958 xref: EMBL:AF127959 xref: EMBL:AF127960 xref: EMBL:AF127961 xref: EMBL:AF127962 xref: EMBL:AF127963 xref: EMBL:AF127964 xref: EMBL:AF127965 xref: EMBL:AF127966 xref: EMBL:AF127967 xref: EMBL:AF127968 xref: EMBL:AF127969 xref: EMBL:AF127970 xref: EMBL:AF127971 xref: EMBL:AF127972 xref: EMBL:AF127973 xref: EMBL:AF127974 xref: EMBL:AF127975 xref: HGNC:HGNC:9177 xref: UniGene:Hs.524871 xref: UniGene:Hs.657680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017087 ! Q9Y5S5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0009009 name: unknown_human def: "Putative uncharacterized protein unknown gene" [UniProtKB:Q9Y6S7] xref: EMBL:AC006530 xref: HGNC:HGNC:7128 xref: UniGene:Hs.436650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018492 ! Q9Y6S7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010892 name: CASP8AP2_human def: "CASP8-associated protein 2 gene" [UniProtKB:Q9UKL3] synonym: "FLASH" EXACT [UniProtKB:Q9UKL3] synonym: "KIAA1315" EXACT [UniProtKB:Q9UKL3] synonym: "RIP25" EXACT [UniProtKB:Q9UKL3] xref: EMBL:AB037736 xref: EMBL:AF154415 xref: EMBL:AF164678 xref: EMBL:AF165161 xref: EMBL:AK002070 xref: EMBL:BC042577 xref: EMBL:BC056685 xref: HGNC:HGNC:1510 xref: UniGene:Hs.558218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035939 ! C8AP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010893 name: ERCC3_human def: "TFIIH basal transcription factor complex helicase XPB subunit gene" [UniProtKB:P19447] synonym: "XPB" EXACT [UniProtKB:P19447] synonym: "XPBC" EXACT [UniProtKB:P19447] xref: EMBL:AY163769 xref: EMBL:BC008820 xref: EMBL:M31899 xref: HGNC:HGNC:3435 xref: UniGene:Hs.469872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028502 ! ERCC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010894 name: KANK1_human def: "KN motif and ankyrin repeat domain-containing protein 1 gene" [UniProtKB:Q14678] synonym: "ANKRD15" EXACT [UniProtKB:Q14678] synonym: "KANK" EXACT [UniProtKB:Q14678] synonym: "KIAA0172" EXACT [UniProtKB:Q14678] xref: EMBL:AL136979 xref: EMBL:BC037495 xref: EMBL:D79994 xref: HGNC:HGNC:19309 xref: UniGene:Hs.306764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001789 ! KANK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010895 name: MEN1_human def: "Menin gene" [UniProtKB:O00255] synonym: "SCG2" EXACT [UniProtKB:O00255] xref: EMBL:BC002544 xref: EMBL:U93236 xref: EMBL:U93237 xref: HGNC:HGNC:7010 xref: UniGene:Hs.423348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035935 ! MEN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010896 name: RBM38_human def: "RNA-binding protein 38 gene" [UniProtKB:Q9H0Z9] synonym: "RNPC1" EXACT [UniProtKB:Q9H0Z9] synonym: "SEB4" EXACT [UniProtKB:Q9H0Z9] xref: EMBL:AF432218 xref: EMBL:AL109955 xref: EMBL:BC018711 xref: EMBL:CH471077 xref: EMBL:X75314 xref: EMBL:X75315 xref: HGNC:HGNC:15818 xref: UniGene:Hs.236361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017902 ! RBM38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010897 name: RNF8_human def: "E3 ubiquitin-protein ligase RNF8 gene" [UniProtKB:O76064] synonym: "KIAA0646" EXACT [UniProtKB:O76064] xref: EMBL:AB012770 xref: EMBL:AB014546 xref: EMBL:AF334675 xref: EMBL:AK222765 xref: EMBL:AL096712 xref: EMBL:BC007517 xref: EMBL:BT007446 xref: EMBL:CH471081 xref: HGNC:HGNC:10071 xref: UniGene:Hs.485278 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035936 ! RNF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010898 name: SETD8_human def: "Histone-lysine N-methyltransferase SETD8 gene" [UniProtKB:Q9NQR1] synonym: "KMT5A" EXACT [UniProtKB:Q9NQR1] synonym: "PRSET7" EXACT [UniProtKB:Q9NQR1] synonym: "SET07" EXACT [UniProtKB:Q9NQR1] synonym: "SET8" EXACT [UniProtKB:Q9NQR1] xref: EMBL:AF287261 xref: EMBL:AY064546 xref: EMBL:AY102937 xref: EMBL:BC050346 xref: HGNC:HGNC:29489 xref: UniGene:Hs.572262 xref: UniGene:Hs.700682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035938 ! SETD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0010899 name: SKP1_human def: "S-phase kinase-associated protein 1 gene" [UniProtKB:P63208] synonym: "EMC19" EXACT [UniProtKB:P63208] synonym: "OCP2" EXACT [UniProtKB:P63208] synonym: "SKP1A" EXACT [UniProtKB:P63208] synonym: "TCEB1L" EXACT [UniProtKB:P63208] xref: EMBL:BC009839 xref: EMBL:BC020798 xref: EMBL:BC025673 xref: EMBL:BC065730 xref: EMBL:U33760 xref: EMBL:U37558 xref: EMBL:Z47087 xref: HGNC:HGNC:10899 xref: UniGene:Hs.171626 xref: UniGene:Hs.643015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005634 ! SKP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011211 name: HTR1D_human def: "5-hydroxytryptamine receptor 1D gene" [UniProtKB:P28221] synonym: "HTR1DA" EXACT [UniProtKB:P28221] synonym: "HTRL" EXACT [UniProtKB:P28221] xref: EMBL:AF498979 xref: EMBL:AL049576 xref: EMBL:BC007720 xref: EMBL:BT007027 xref: EMBL:M81589 xref: EMBL:M89955 xref: HGNC:HGNC:5289 xref: UniGene:Hs.121482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038266 ! 5HT1D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011212 name: HTR2C_human def: "5-hydroxytryptamine receptor 2C gene" [UniProtKB:P28335] synonym: "HTR1C" EXACT [UniProtKB:P28335] xref: EMBL:AC004822 xref: EMBL:AF208053 xref: EMBL:AF498983 xref: EMBL:AK295753 xref: EMBL:AL355812 xref: EMBL:AL590097 xref: EMBL:BC095543 xref: EMBL:M81778 xref: EMBL:U49516 xref: EMBL:X80763 xref: HGNC:HGNC:5295 xref: UniGene:Hs.149037 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038260 ! 5HT2C_HUMAN relationship: codes_for CCO:B0054256 ! B1AMW4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011213 name: SCG5_human def: "Neuroendocrine protein 7B2 precursor gene" [UniProtKB:P05408] synonym: "SGNE1" EXACT [UniProtKB:P05408] xref: EMBL:AJ290438 xref: EMBL:AJ290439 xref: EMBL:AJ290440 xref: EMBL:AJ290441 xref: EMBL:AJ290442 xref: EMBL:BC005349 xref: EMBL:Y00757 xref: HGNC:HGNC:10816 xref: UniGene:Hs.156540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037954 ! 7B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011218 name: ABI2_human def: "Abl interactor 2 gene" [UniProtKB:Q9NYB9] synonym: "ARGBPIA" EXACT [UniProtKB:Q9NYB9] xref: EMBL:AF260261 xref: EMBL:BC001439 xref: EMBL:BT009920 xref: EMBL:U23435 xref: EMBL:U31089 xref: EMBL:X95632 xref: HGNC:HGNC:24011 xref: UniGene:Hs.471156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038095 ! ABI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011219 name: ABI3_human def: "ABI gene family member 3 gene" [UniProtKB:Q9P2A4] synonym: "NESH" EXACT [UniProtKB:Q9P2A4] xref: EMBL:AB037886 xref: EMBL:AL136709 xref: EMBL:BC007780 xref: HGNC:HGNC:29859 xref: UniGene:Hs.130719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038093 ! ABI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011222 name: ACVR1C_human def: "Activin receptor type-1C precursor gene" [UniProtKB:Q8NER5] synonym: "ALK7" EXACT [UniProtKB:Q8NER5] xref: EMBL:AC019186 xref: EMBL:AC079750 xref: EMBL:AF525679 xref: EMBL:AF525680 xref: EMBL:AF525681 xref: EMBL:AY127050 xref: EMBL:BC022530 xref: HGNC:HGNC:18123 xref: UniGene:Hs.352338 xref: UniGene:Hs.541710 xref: UniGene:Hs.562901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020368 ! ACV1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011223 name: ACVRL1_human def: "Serine/threonine-protein kinase receptor R3 precursor gene" [UniProtKB:P37023] synonym: "ACVRLK1" EXACT [UniProtKB:P37023] synonym: "ALK1" EXACT [UniProtKB:P37023] xref: EMBL:AC025259 xref: EMBL:BC042637 xref: EMBL:CH471111 xref: EMBL:L17075 xref: EMBL:U77707 xref: EMBL:U77708 xref: EMBL:U77709 xref: EMBL:U77710 xref: EMBL:U77711 xref: EMBL:U77712 xref: EMBL:U77713 xref: EMBL:Z22533 xref: HGNC:HGNC:175 xref: UniGene:Hs.591026 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020366 ! ACVL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011224 name: ADAM11_human def: "ADAM 11 precursor gene" [UniProtKB:O75078] synonym: "MDC" EXACT [UniProtKB:O75078] xref: EMBL:AB009675 xref: EMBL:D17390 xref: EMBL:D31872 xref: HGNC:HGNC:189 xref: UniGene:Hs.6088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038563 ! ADA11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011225 name: ADRA1A_human def: "Alpha-1A adrenergic receptor gene" [UniProtKB:P35348] synonym: "ADRA1C" EXACT [UniProtKB:P35348] xref: EMBL:AB065703 xref: EMBL:AF013261 xref: EMBL:AY389505 xref: EMBL:AY491775 xref: EMBL:AY491776 xref: EMBL:AY491777 xref: EMBL:AY491778 xref: EMBL:AY491779 xref: EMBL:AY491780 xref: EMBL:AY491781 xref: EMBL:D25235 xref: EMBL:D32201 xref: EMBL:D32202 xref: EMBL:EU326301 xref: EMBL:L31774 xref: EMBL:U02569 xref: EMBL:U03866 xref: HGNC:HGNC:277 xref: UniGene:Hs.654357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038258 ! ADA1A_HUMAN relationship: codes_for CCO:B0054198 ! B0ZBD2_HUMAN relationship: codes_for CCO:B0054199 ! B0ZBD3_HUMAN relationship: codes_for CCO:B0054200 ! B0ZBD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011226 name: ADRA1B_human def: "Alpha-1B adrenergic receptor gene" [UniProtKB:P35368] xref: EMBL:L31773 xref: EMBL:M99589 xref: EMBL:M99590 xref: EMBL:U03865 xref: HGNC:HGNC:278 xref: UniGene:Hs.368632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038263 ! ADA1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011227 name: ADRA1D_human def: "Alpha-1D adrenergic receptor gene" [UniProtKB:P25100] synonym: "ADRA1A" EXACT [UniProtKB:P25100] xref: EMBL:AL121675 xref: EMBL:AL357040 xref: EMBL:D29952 xref: EMBL:L31772 xref: EMBL:M76446 xref: EMBL:S70782 xref: EMBL:U03864 xref: HGNC:HGNC:280 xref: UniGene:Hs.557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038265 ! ADA1D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011230 name: ADAM22_human def: "ADAM 22 precursor gene" [UniProtKB:Q9P0K1] synonym: "MDC2" EXACT [UniProtKB:Q9P0K1] xref: EMBL:AB009671 xref: EMBL:AF073291 xref: EMBL:AF155381 xref: EMBL:AF155382 xref: EMBL:AF158637 xref: HGNC:HGNC:201 xref: UniGene:Hs.592282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038558 ! ADA22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011233 name: ADRA2B_human def: "Alpha-2B adrenergic receptor gene" [UniProtKB:P18089] synonym: "ADRA2L1" EXACT [UniProtKB:P18089] synonym: "ADRA2RL1" EXACT [UniProtKB:P18089] xref: EMBL:AC092603 xref: EMBL:AF005900 xref: EMBL:AF316895 xref: EMBL:AY548167 xref: EMBL:DQ057076 xref: EMBL:M34041 xref: EMBL:M38742 xref: HGNC:HGNC:282 xref: UniGene:Hs.247686 xref: UniGene:Hs.673848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038267 ! ADA2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011236 name: ADCK1_human def: "Uncharacterized aarF domain-containing protein kinase 1 precursor gene" [UniProtKB:Q86TW2] xref: EMBL:BC058906 xref: EMBL:BX248292 xref: HGNC:HGNC:19038 xref: UniGene:Hs.413208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038785 ! ADCK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011237 name: ADH5_human def: "Alcohol dehydrogenase class-3 gene" [UniProtKB:P11766] synonym: "ADHX" EXACT [UniProtKB:P11766] synonym: "FDH" EXACT [UniProtKB:P11766] xref: EMBL:AY987960 xref: EMBL:BC014665 xref: EMBL:BT019832 xref: EMBL:CR541689 xref: EMBL:M29872 xref: EMBL:M30471 xref: EMBL:M81112 xref: EMBL:M81113 xref: EMBL:M81114 xref: EMBL:M81115 xref: EMBL:M81116 xref: EMBL:M81117 xref: EMBL:M81118 xref: HGNC:HGNC:253 xref: UniGene:Hs.78989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038020 ! ADHX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011243 name: PRMT6_human def: "Protein arginine N-methyltransferase 6 gene" [UniProtKB:Q96LA8] synonym: "HRMT1L6" EXACT [UniProtKB:Q96LA8] xref: EMBL:AK001421 xref: EMBL:AL355539 xref: EMBL:AY043278 xref: EMBL:BC002729 xref: EMBL:BC073866 xref: EMBL:CH471156 xref: HGNC:HGNC:18241 xref: UniGene:Hs.26006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036272 ! ANM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011246 name: TFAP2D_human def: "Transcription factor AP-2 delta gene" [UniProtKB:Q7Z6R9] synonym: "TFAP2BL1" EXACT [UniProtKB:Q7Z6R9] xref: EMBL:AL031224 xref: EMBL:AY028376 xref: EMBL:CH471081 xref: HGNC:HGNC:15581 xref: UniGene:Hs.434107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038044 ! AP2D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011247 name: TFAP2E_human def: "Transcription factor AP-2 epsilon gene" [UniProtKB:Q6VUC0] xref: EMBL:AC004865 xref: EMBL:AL157951 xref: EMBL:AY326454 xref: EMBL:BC041175 xref: EMBL:CH471059 xref: HGNC:HGNC:30774 xref: UniGene:Hs.567844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038043 ! AP2E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011249 name: ARPC1A_human def: "Actin-related protein 2/3 complex subunit 1A gene" [UniProtKB:Q92747] synonym: "SOP2L" EXACT [UniProtKB:Q92747] xref: EMBL:BC039594 xref: EMBL:BC047889 xref: EMBL:BC054027 xref: EMBL:Y08999 xref: HGNC:HGNC:703 xref: UniGene:Hs.124126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031598 ! ARC1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011250 name: ARPC1B_human def: "Actin-related protein 2/3 complex subunit 1B gene" [UniProtKB:O15143] synonym: "ARC41" EXACT [UniProtKB:O15143] xref: EMBL:AC004922 xref: EMBL:AF006084 xref: EMBL:BC002562 xref: EMBL:BC002988 xref: EMBL:BC007555 xref: HGNC:HGNC:704 xref: UniGene:Hs.489284 xref: UniGene:Hs.696405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031593 ! ARC1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011251 name: ARHGEF4_human def: "Rho guanine nucleotide exchange factor 4 gene" [UniProtKB:Q9NR80] synonym: "KIAA1112" EXACT [UniProtKB:Q9NR80] xref: EMBL:AB029035 xref: EMBL:AB042199 xref: EMBL:AF249745 xref: HGNC:HGNC:684 xref: UniGene:Hs.469935 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037017 ! ARHG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011252 name: ARHGEF9_human def: "Rho guanine nucleotide exchange factor 9 gene" [UniProtKB:O43307] synonym: "KIAA0424" EXACT [UniProtKB:O43307] xref: EMBL:AB007884 xref: EMBL:AK295178 xref: EMBL:AL355142 xref: EMBL:AL391277 xref: EMBL:AL451106 xref: EMBL:BC117406 xref: HGNC:HGNC:14561 xref: UniGene:Hs.54697 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037024 ! ARHG9_HUMAN relationship: codes_for CCO:B0054254 ! B1AMR3_HUMAN relationship: codes_for CCO:B0054255 ! B1AMR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011260 name: BCL6B_human def: "B-cell CLL/lymphoma 6 member B protein gene" [UniProtKB:Q8N143] synonym: "BAZF" EXACT [UniProtKB:Q8N143] synonym: "ZNF62" EXACT [UniProtKB:Q8N143] xref: EMBL:AB076580 xref: EMBL:AB076581 xref: EMBL:BC059404 xref: HGNC:HGNC:1002 xref: UniGene:Hs.22575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022832 ! BCL6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011261 name: TGFBI_human def: "Transforming growth factor-beta-induced protein ig-h3 precursor gene" [UniProtKB:Q15582] synonym: "BIGH3" EXACT [UniProtKB:Q15582] xref: EMBL:AC004503 xref: EMBL:AC005219 xref: EMBL:AF035626 xref: EMBL:AF035627 xref: EMBL:AF035628 xref: EMBL:AF035629 xref: EMBL:AY149344 xref: EMBL:BC000097 xref: EMBL:BC004972 xref: EMBL:M77349 xref: HGNC:HGNC:11771 xref: UniGene:Hs.369397 xref: UniGene:Hs.645734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037751 ! BGH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011262 name: BMPR1B_human def: "Bone morphogenetic protein receptor type-1B precursor gene" [UniProtKB:O00238] xref: EMBL:BC047773 xref: EMBL:BC069796 xref: EMBL:BC069803 xref: EMBL:D89675 xref: EMBL:U89326 xref: HGNC:HGNC:1077 xref: UniGene:Hs.661426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020371 ! BMR1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011264 name: BRPF1_human def: "Peregrin gene" [UniProtKB:P55201] synonym: "BR140" EXACT [UniProtKB:P55201] xref: EMBL:AF176815 xref: EMBL:M91585 xref: HGNC:HGNC:14255 xref: UniGene:Hs.1004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038294 ! BRPF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011267 name: BSX_human def: "Brain-specific homeobox protein homolog gene" [UniProtKB:Q3C1V8] synonym: "BSX1" EXACT [UniProtKB:Q3C1V8] xref: EMBL:AB231738 xref: EMBL:AP003040 xref: HGNC:HGNC:20450 xref: UniGene:Hs.449687 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037985 ! BSH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011268 name: CAP1_human def: "Adenylyl cyclase-associated protein 1 gene" [UniProtKB:Q01518] synonym: "CAP" EXACT [UniProtKB:Q01518] xref: EMBL:AK222513 xref: EMBL:AL512599 xref: EMBL:BC013963 xref: EMBL:BC095440 xref: EMBL:BT007152 xref: EMBL:CR457409 xref: EMBL:L12168 xref: EMBL:M98474 xref: HGNC:HGNC:20040 xref: UniGene:Hs.370581 xref: UniGene:Hs.701264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023915 ! CAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011269 name: CAP2_human def: "Adenylyl cyclase-associated protein 2 gene" [UniProtKB:P40123] xref: EMBL:BC008481 xref: EMBL:CR457022 xref: EMBL:U02390 xref: HGNC:HGNC:20039 xref: UniGene:Hs.132902 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023918 ! CAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011270 name: CAPZA1_human def: "F-actin-capping protein subunit alpha-1 gene" [UniProtKB:P52907] xref: EMBL:AK223226 xref: EMBL:AL603832 xref: EMBL:AL929470 xref: EMBL:BC000144 xref: EMBL:BT019364 xref: EMBL:CR407657 xref: EMBL:CR541819 xref: EMBL:U56637 xref: HGNC:HGNC:1488 xref: UniGene:Hs.514934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037567 ! CAZA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011271 name: CAPZA3_human def: "F-actin-capping protein subunit alpha-3 gene" [UniProtKB:Q96KX2] synonym: "CAPAA3" EXACT [UniProtKB:Q96KX2] synonym: "GSG3" EXACT [UniProtKB:Q96KX2] xref: EMBL:AB053259 xref: EMBL:AK058174 xref: EMBL:BC016745 xref: HGNC:HGNC:24205 xref: UniGene:Hs.131288 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037556 ! CAZA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011273 name: CPZ_human def: "Carboxypeptidase Z precursor gene" [UniProtKB:Q66K79] xref: EMBL:AC105345 xref: EMBL:AK056317 xref: EMBL:BC080539 xref: EMBL:U83411 xref: HGNC:HGNC:2333 xref: UniGene:Hs.78068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038579 ! CBPZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011275 name: CDC14B_human def: "Dual specificity protein phosphatase CDC14B gene" [UniProtKB:O60729] xref: EMBL:AF023158 xref: EMBL:AF064104 xref: EMBL:AF064105 xref: EMBL:AL133477 xref: EMBL:AL353578 xref: EMBL:AY675321 xref: EMBL:EF611343 xref: HGNC:HGNC:1719 xref: UniGene:Hs.40582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018148 ! Q5JU07_HUMAN relationship: codes_for CCO:B0018153 ! Q5JU06_HUMAN relationship: codes_for CCO:B0018160 ! CC14B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011280 name: CCL11_human def: "Eotaxin precursor gene" [UniProtKB:P51671] synonym: "SCYA11" EXACT [UniProtKB:P51671] xref: EMBL:BC017850 xref: EMBL:D49372 xref: EMBL:U34780 xref: EMBL:U46572 xref: EMBL:U46573 xref: EMBL:Z69291 xref: EMBL:Z75668 xref: EMBL:Z75669 xref: EMBL:Z92709 xref: HGNC:HGNC:10610 xref: UniGene:Hs.54460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038969 ! CCL11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011281 name: CCL13_human def: "C-C motif chemokine 13 precursor gene" [UniProtKB:Q99616] synonym: "MCP4" EXACT [UniProtKB:Q99616] synonym: "NCC1" EXACT [UniProtKB:Q99616] synonym: "SCYA13" EXACT [UniProtKB:Q99616] xref: EMBL:AC002482 xref: EMBL:AJ001634 xref: EMBL:BC008621 xref: EMBL:BT007385 xref: EMBL:U46767 xref: EMBL:U59808 xref: EMBL:X98306 xref: EMBL:Z77650 xref: HGNC:HGNC:10611 xref: UniGene:Hs.414629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038966 ! CCL13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011283 name: CCL2_human def: "C-C motif chemokine 2 precursor gene" [UniProtKB:P13500] synonym: "MCP1" EXACT [UniProtKB:P13500] synonym: "SCYA2" EXACT [UniProtKB:P13500] xref: EMBL:A17786 xref: EMBL:AF519531 xref: EMBL:BC009716 xref: EMBL:BT007329 xref: EMBL:M24545 xref: EMBL:M28223 xref: EMBL:M28224 xref: EMBL:M28225 xref: EMBL:M28226 xref: EMBL:M30816 xref: EMBL:M31625 xref: EMBL:M31626 xref: EMBL:M37719 xref: EMBL:S69738 xref: EMBL:S71513 xref: EMBL:X14768 xref: EMBL:Y18933 xref: HGNC:HGNC:10618 xref: UniGene:Hs.303649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038965 ! CCL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011284 name: CCL7_human def: "C-C motif chemokine 7 precursor gene" [UniProtKB:P80098] synonym: "MCP3" EXACT [UniProtKB:P80098] synonym: "SCYA6" EXACT [UniProtKB:P80098] synonym: "SCYA7" EXACT [UniProtKB:P80098] xref: EMBL:AF043338 xref: EMBL:BC092436 xref: EMBL:BC112258 xref: EMBL:BC112260 xref: EMBL:X71087 xref: EMBL:X72308 xref: EMBL:X72309 xref: HGNC:HGNC:10634 xref: UniGene:Hs.251526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038963 ! CCL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011285 name: CCL8_human def: "C-C motif chemokine 8 precursor gene" [UniProtKB:P80075] synonym: "MCP2" EXACT [UniProtKB:P80075] synonym: "SCYA10" EXACT [UniProtKB:P80075] synonym: "SCYA8" EXACT [UniProtKB:P80075] xref: EMBL:BC126242 xref: EMBL:X99886 xref: EMBL:Y10802 xref: EMBL:Y16645 xref: HGNC:HGNC:10635 xref: UniGene:Hs.699804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038971 ! CCL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011291 name: CDX1_human def: "Homeobox protein CDX-1 gene" [UniProtKB:P47902] xref: EMBL:AF239666 xref: EMBL:BC096250 xref: EMBL:BC096251 xref: EMBL:BC096252 xref: EMBL:BC127122 xref: EMBL:U15212 xref: EMBL:U16360 xref: EMBL:U51095 xref: HGNC:HGNC:1805 xref: UniGene:Hs.1545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036803 ! Q4VAU3_HUMAN relationship: codes_for CCO:B0036807 ! CDX1_HUMAN relationship: codes_for CCO:B0056329 ! Q4VAU5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011292 name: CDX2_human def: "Homeobox protein CDX-2 gene" [UniProtKB:Q99626] synonym: "CDX3" EXACT [UniProtKB:Q99626] xref: EMBL:AF007884 xref: EMBL:AF007885 xref: EMBL:AF007886 xref: EMBL:AJ278431 xref: EMBL:AJ278432 xref: EMBL:AJ278434 xref: EMBL:AL591024 xref: EMBL:BC014461 xref: EMBL:U51096 xref: EMBL:Y13709 xref: HGNC:HGNC:1806 xref: UniGene:Hs.174249 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036829 ! CDX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011294 name: CARHSP1_human def: "Calcium-regulated heat stable protein 1 gene" [UniProtKB:Q9Y2V2] xref: EMBL:AF115345 xref: EMBL:BC003366 xref: EMBL:BC108283 xref: HGNC:HGNC:17150 xref: UniGene:Hs.632184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021340 ! CHSP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011295 name: CLCN3_human def: "Chloride channel protein 3 gene" [UniProtKB:P51790] xref: EMBL:AB019542 xref: EMBL:AF029346 xref: EMBL:AF172729 xref: EMBL:X78520 xref: HGNC:HGNC:2021 xref: UniGene:Hs.481186 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037912 ! CLCN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011300 name: PDE6H_human def: "Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma gene" [UniProtKB:Q13956] xref: EMBL:BC069774 xref: EMBL:BC069800 xref: EMBL:BC093738 xref: EMBL:BC093740 xref: EMBL:D45399 xref: HGNC:HGNC:8790 xref: UniGene:Hs.54471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037430 ! CNCG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011305 name: PDE6G_human def: "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma gene" [UniProtKB:P18545] synonym: "PDEG" EXACT [UniProtKB:P18545] xref: EMBL:BC106884 xref: EMBL:M36476 xref: EMBL:U00481 xref: EMBL:U00482 xref: EMBL:X62025 xref: HGNC:HGNC:8789 xref: UniGene:Hs.654482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037429 ! CNRG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011306 name: C3_human def: "Complement C3 precursor gene" [UniProtKB:P01024] synonym: "CPAMD1" EXACT [UniProtKB:P01024] xref: EMBL:AY513239 xref: EMBL:K02765 xref: HGNC:HGNC:1318 xref: UniGene:Hs.529053 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036109 ! CO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011309 name: COPA_human def: "Coatomer subunit alpha gene" [UniProtKB:P53621] xref: EMBL:AL445230 xref: EMBL:AL513282 xref: EMBL:BC038447 xref: EMBL:CH471121 xref: EMBL:U24105 xref: HGNC:HGNC:2230 xref: UniGene:Hs.162121 xref: UniGene:Hs.685025 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038202 ! COPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011314 name: CIAPIN1_human def: "Anamorsin gene" [UniProtKB:Q6FI81] synonym: "CUA001" EXACT [UniProtKB:Q6FI81] synonym: "PRO0915" EXACT [UniProtKB:Q6FI81] xref: EMBL:AC004382 xref: EMBL:AF116609 xref: EMBL:AF248964 xref: EMBL:AL136613 xref: EMBL:BC002568 xref: EMBL:BC024196 xref: EMBL:BC067303 xref: EMBL:BC071740 xref: EMBL:CR533545 xref: HGNC:HGNC:28050 xref: UniGene:Hs.4900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019428 ! CPIN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011324 name: CPVL_human def: "Probable serine carboxypeptidase CPVL precursor gene" [UniProtKB:Q9H3G5] synonym: "PSEC0124" EXACT [UniProtKB:Q9H3G5] synonym: "UNQ197/PRO223" EXACT [UniProtKB:Q9H3G5] synonym: "VLP" EXACT [UniProtKB:Q9H3G5] xref: EMBL:AF106704 xref: EMBL:AF282617 xref: EMBL:AK075433 xref: EMBL:AY358549 xref: EMBL:BC016838 xref: HGNC:HGNC:14399 xref: UniGene:Hs.233389 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038468 ! CPVL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011329 name: CSDC2_human def: "Cold shock domain-containing protein C2 gene" [UniProtKB:Q9Y534] synonym: "PIPPIN" EXACT [UniProtKB:Q9Y534] xref: EMBL:AB027011 xref: EMBL:AL023553 xref: EMBL:AL834417 xref: EMBL:BC067113 xref: EMBL:CR456457 xref: HGNC:HGNC:30359 xref: UniGene:Hs.310893 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021341 ! CSDC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011330 name: CSF1_human def: "Macrophage colony-stimulating factor 1 precursor gene" [UniProtKB:P09603] xref: EMBL:BC021117 xref: EMBL:M11038 xref: EMBL:M11295 xref: EMBL:M11296 xref: EMBL:M27087 xref: EMBL:M37435 xref: EMBL:M64592 xref: EMBL:M76453 xref: EMBL:U22386 xref: EMBL:X05825 xref: EMBL:X06106 xref: HGNC:HGNC:2432 xref: UniGene:Hs.591402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038878 ! CSF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011331 name: CLSTN1_human def: "Calsyntenin-1 precursor gene" [UniProtKB:O94985] synonym: "CS1" EXACT [UniProtKB:O94985] synonym: "KIAA0911" EXACT [UniProtKB:O94985] xref: EMBL:AB020718 xref: EMBL:AF438482 xref: EMBL:AK289798 xref: EMBL:AL357140 xref: EMBL:AL691449 xref: EMBL:AY753301 xref: EMBL:BC033902 xref: HGNC:HGNC:17447 xref: UniGene:Hs.29665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038991 ! CSTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011336 name: CYFIP1_human def: "Cytoplasmic FMR1-interacting protein 1 gene" [UniProtKB:Q7L576] synonym: "KIAA0068" EXACT [UniProtKB:Q7L576] xref: EMBL:AK127094 xref: EMBL:AY763577 xref: EMBL:AY763578 xref: EMBL:AY763579 xref: EMBL:AY763580 xref: EMBL:BC001306 xref: EMBL:BC005097 xref: EMBL:D38549 xref: HGNC:HGNC:13759 xref: UniGene:Hs.26704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037573 ! CYFP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011340 name: DAPK2_human def: "Death-associated protein kinase 2 gene" [UniProtKB:Q9UIK4] xref: EMBL:AB018001 xref: EMBL:AF052941 xref: EMBL:BC114506 xref: HGNC:HGNC:2675 xref: UniGene:Hs.237886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036525 ! DAPK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011341 name: DBX1_human def: "Homeobox protein DBX1 gene" [UniProtKB:A6NMT0] xref: EMBL:AC068860 xref: HGNC:HGNC:33185 xref: UniGene:Hs.558604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037981 ! DBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011343 name: DEPDC6_human def: "DEP domain-containing protein 6 gene" [UniProtKB:Q8TB45] xref: EMBL:AK022490 xref: EMBL:AK023916 xref: EMBL:AL136678 xref: EMBL:BC012040 xref: EMBL:BC024746 xref: HGNC:HGNC:22953 xref: UniGene:Hs.112981 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037020 ! DEPD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011348 name: DNAJB12_human def: "DnaJ homolog subfamily B member 12 gene" [UniProtKB:Q9NXW2] xref: EMBL:AK000034 xref: EMBL:AK025942 xref: EMBL:BC011812 xref: EMBL:BC064920 xref: HGNC:HGNC:14891 xref: UniGene:Hs.696014 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037130 ! DJB12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011352 name: DLL1_human def: "Delta-like protein 1 precursor gene" [UniProtKB:O00548] synonym: "UNQ146/PRO172" EXACT [UniProtKB:O00548] xref: EMBL:AF003522 xref: EMBL:AF196571 xref: EMBL:AF222310 xref: EMBL:AL078605 xref: EMBL:AY358892 xref: HGNC:HGNC:2908 xref: UniGene:Hs.379912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028292 ! DLL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011353 name: DLL4_human def: "Delta-like protein 4 precursor gene" [UniProtKB:Q9NR61] synonym: "UNQ1895/PRO4341" EXACT [UniProtKB:Q9NR61] xref: EMBL:AB036931 xref: EMBL:AB043894 xref: EMBL:AF253468 xref: EMBL:AF279305 xref: EMBL:AY358894 xref: EMBL:BC106950 xref: HGNC:HGNC:2910 xref: UniGene:Hs.511076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028291 ! DLL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011354 name: DLX2_human def: "Homeobox protein DLX-2 gene" [UniProtKB:Q07687] xref: EMBL:BC032558 xref: EMBL:L07919 xref: EMBL:U51003 xref: HGNC:HGNC:2915 xref: UniGene:Hs.419 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037982 ! DLX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011355 name: DLX3_human def: "Homeobox protein DLX-3 gene" [UniProtKB:O60479] xref: EMBL:AF028233 xref: EMBL:AF452638 xref: EMBL:BC012361 xref: EMBL:BC028970 xref: HGNC:HGNC:2916 xref: UniGene:Hs.134194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037990 ! DLX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011356 name: DLX4_human def: "Homeobox protein DLX-4 gene" [UniProtKB:Q92988] synonym: "BP1" EXACT [UniProtKB:Q92988] synonym: "DLX7" EXACT [UniProtKB:Q92988] synonym: "DLX8" EXACT [UniProtKB:Q92988] synonym: "DLX9" EXACT [UniProtKB:Q92988] xref: EMBL:AF028235 xref: EMBL:AF254115 xref: EMBL:AF452638 xref: EMBL:BC005812 xref: EMBL:BC014419 xref: EMBL:BC016145 xref: EMBL:BT006978 xref: EMBL:U31762 xref: EMBL:U73328 xref: HGNC:HGNC:2917 xref: UniGene:Hs.591167 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037984 ! DLX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011357 name: DLX5_human def: "Homeobox protein DLX-5 gene" [UniProtKB:P56178] xref: EMBL:AC004774 xref: EMBL:AK023493 xref: EMBL:BC006226 xref: HGNC:HGNC:2918 xref: UniGene:Hs.99348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037989 ! DLX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011358 name: DLX6_human def: "Homeobox protein DLX-6 gene" [UniProtKB:P56179] xref: EMBL:AC004774 xref: EMBL:BC069363 xref: EMBL:BC103688 xref: EMBL:BC103689 xref: EMBL:BC103690 xref: EMBL:BC109381 xref: EMBL:CH236949 xref: HGNC:HGNC:2919 xref: UniGene:Hs.249196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037983 ! DLX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011359 name: DNMT3A_human def: "DNA (cytosine-5)-methyltransferase 3A gene" [UniProtKB:Q9Y6K1] xref: EMBL:AC012074 xref: EMBL:AF067972 xref: EMBL:AF331856 xref: EMBL:AF480163 xref: EMBL:BC043617 xref: EMBL:CH471053 xref: HGNC:HGNC:2978 xref: UniGene:Hs.515840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037706 ! DNM3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011360 name: DNMT3L_human def: "DNA (cytosine-5)-methyltransferase 3-like gene" [UniProtKB:Q9UJW3] xref: EMBL:AF194032 xref: EMBL:AP001753 xref: EMBL:BC002560 xref: HGNC:HGNC:2980 xref: UniGene:Hs.592165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037714 ! DNM3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011365 name: DPP4_human def: "Dipeptidyl peptidase 4 gene" [UniProtKB:P27487] synonym: "ADCP2" EXACT [UniProtKB:P27487] synonym: "CD26" EXACT [UniProtKB:P27487] xref: EMBL:BC013329 xref: EMBL:BC065265 xref: EMBL:M74777 xref: EMBL:M80536 xref: EMBL:S79876 xref: EMBL:U13710 xref: EMBL:U13711 xref: EMBL:U13712 xref: EMBL:U13713 xref: EMBL:U13714 xref: EMBL:U13715 xref: EMBL:U13716 xref: EMBL:U13717 xref: EMBL:U13718 xref: EMBL:U13719 xref: EMBL:U13720 xref: EMBL:U13721 xref: EMBL:U13722 xref: EMBL:U13723 xref: EMBL:U13724 xref: EMBL:U13725 xref: EMBL:U13726 xref: EMBL:U13727 xref: EMBL:U13728 xref: EMBL:U13729 xref: EMBL:U13730 xref: EMBL:U13731 xref: EMBL:U13732 xref: EMBL:U13733 xref: EMBL:U13734 xref: EMBL:U13735 xref: EMBL:X60708 xref: HGNC:HGNC:3009 xref: UniGene:Hs.368912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038734 ! DPP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011368 name: DUSP16_human def: "Dual specificity protein phosphatase 16 gene" [UniProtKB:Q9BY84] synonym: "KIAA1700" EXACT [UniProtKB:Q9BY84] synonym: "MKP7" EXACT [UniProtKB:Q9BY84] xref: EMBL:AB051487 xref: EMBL:AB052156 xref: EMBL:AF506796 xref: EMBL:BC109235 xref: HGNC:HGNC:17909 xref: UniGene:Hs.536535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037152 ! DUS16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011372 name: DUSP8_human def: "Dual specificity protein phosphatase 8 gene" [UniProtKB:Q13202] synonym: "VH5" EXACT [UniProtKB:Q13202] xref: EMBL:U27193 xref: HGNC:HGNC:3074 xref: UniGene:Hs.41688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037159 ! DUS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011378 name: ESRRA_human def: "Steroid hormone receptor ERR1 gene" [UniProtKB:P11474] synonym: "ERR1" EXACT [UniProtKB:P11474] synonym: "ESRL1" EXACT [UniProtKB:P11474] synonym: "NR3B1" EXACT [UniProtKB:P11474] xref: EMBL:AP001453 xref: EMBL:BC063795 xref: EMBL:BC092470 xref: EMBL:BC093720 xref: EMBL:BC093722 xref: EMBL:CH471076 xref: EMBL:DQ514553 xref: EMBL:L38487 xref: EMBL:X51416 xref: HGNC:HGNC:3471 xref: UniGene:Hs.110849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038837 ! Q569H8_HUMAN relationship: codes_for CCO:B0038838 ! ERR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011379 name: ESRRB_human def: "Steroid hormone receptor ERR2 gene" [UniProtKB:O95718] synonym: "ERRB2" EXACT [UniProtKB:O95718] synonym: "ESRL2" EXACT [UniProtKB:O95718] synonym: "NR3B2" EXACT [UniProtKB:O95718] xref: EMBL:AC008050 xref: EMBL:AC016543 xref: EMBL:AF094517 xref: EMBL:AY451390 xref: HGNC:HGNC:3473 xref: UniGene:Hs.435845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038843 ! ERR2_HUMAN relationship: codes_for CCO:B0038845 ! Q5F0P7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011380 name: ESRRG_human def: "Estrogen-related receptor gamma gene" [UniProtKB:P62508] synonym: "ERR3" EXACT [UniProtKB:P62508] synonym: "ERRG2" EXACT [UniProtKB:P62508] synonym: "KIAA0832" EXACT [UniProtKB:P62508] synonym: "NR3B3" EXACT [UniProtKB:P62508] xref: EMBL:AB020639 xref: EMBL:AC096635 xref: EMBL:AF058291 xref: EMBL:AF094518 xref: EMBL:AF117255 xref: EMBL:AL445650 xref: EMBL:AL512650 xref: EMBL:AY388456 xref: EMBL:AY388457 xref: EMBL:AY388458 xref: EMBL:AY388459 xref: EMBL:AY388460 xref: EMBL:AY388461 xref: EMBL:AY528719 xref: EMBL:BC008218 xref: EMBL:BC064700 xref: EMBL:CR749497 xref: HGNC:HGNC:3474 xref: UniGene:Hs.444225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038846 ! ERR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011382 name: EXOC5_human def: "Exocyst complex component 5 gene" [UniProtKB:O00471] synonym: "SEC10" EXACT [UniProtKB:O00471] synonym: "SEC10L1" EXACT [UniProtKB:O00471] xref: EMBL:U85946 xref: HGNC:HGNC:10696 xref: UniGene:Hs.655158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036875 ! EXOC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011385 name: FAM96B_human def: "UPF0195 protein FAM96B gene" [UniProtKB:Q9Y3D0] synonym: "CGI-128" EXACT [UniProtKB:Q9Y3D0] synonym: "HSPC118" EXACT [UniProtKB:Q9Y3D0] xref: EMBL:AF151886 xref: EMBL:AF161467 xref: EMBL:BC001733 xref: EMBL:BC005023 xref: HGNC:HGNC:24261 xref: UniGene:Hs.9825 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038937 ! FA96B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011389 name: FOXI2_human def: "Forkhead box protein I2 gene" [UniProtKB:Q6ZQN5] xref: EMBL:AK128865 xref: EMBL:AL391005 xref: HGNC:HGNC:32448 xref: UniGene:Hs.449674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038425 ! FOXI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011390 name: FOXJ1_human def: "Forkhead box protein J1 gene" [UniProtKB:Q92949] synonym: "FKHL13" EXACT [UniProtKB:Q92949] synonym: "HFH4" EXACT [UniProtKB:Q92949] xref: EMBL:AJ272064 xref: EMBL:BC046460 xref: EMBL:U69537 xref: EMBL:X99349 xref: EMBL:X99350 xref: EMBL:X99351 xref: HGNC:HGNC:3816 xref: UniGene:Hs.651204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039142 ! FOXJ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011391 name: FOXJ2_human def: "Forkhead box protein J2 gene" [UniProtKB:Q9P0K8] synonym: "FHX" EXACT [UniProtKB:Q9P0K8] xref: EMBL:AF155132 xref: EMBL:AF155133 xref: EMBL:AL161978 xref: EMBL:BC126396 xref: HGNC:HGNC:24818 xref: UniGene:Hs.120844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039140 ! FOXJ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011392 name: FOXJ3_human def: "Forkhead box protein J3 gene" [UniProtKB:Q9UPW0] synonym: "KIAA1041" EXACT [UniProtKB:Q9UPW0] xref: EMBL:AB028964 xref: EMBL:AL157422 xref: EMBL:BC014182 xref: EMBL:BC151828 xref: EMBL:BC152441 xref: HGNC:HGNC:29178 xref: UniGene:Hs.26023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039141 ! FOXJ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011393 name: FOXK1_human def: "Forkhead box protein K1 gene" [UniProtKB:P85037] synonym: "MNF" EXACT [UniProtKB:P85037] xref: EMBL:AC072054 xref: EMBL:AC092428 xref: EMBL:AC092610 xref: EMBL:AK122663 xref: EMBL:AW206906 xref: EMBL:BC038434 xref: EMBL:CB959941 xref: HGNC:HGNC:23480 xref: UniGene:Hs.705471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015239 ! FOXK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011394 name: FOXK2_human def: "Forkhead box protein K2 gene" [UniProtKB:Q01167] synonym: "ILF" EXACT [UniProtKB:Q01167] synonym: "ILF1" EXACT [UniProtKB:Q01167] xref: EMBL:AC124287 xref: EMBL:U58196 xref: EMBL:U58197 xref: EMBL:U58198 xref: EMBL:X60787 xref: HGNC:HGNC:6036 xref: UniGene:Hs.696000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015238 ! FOXK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011395 name: FOXP1_human def: "Forkhead box protein P1 gene" [UniProtKB:Q9H334] synonym: "HSPC215" EXACT [UniProtKB:Q9H334] xref: EMBL:AF146696 xref: EMBL:AF146697 xref: EMBL:AF146698 xref: EMBL:AF151049 xref: EMBL:AF275309 xref: EMBL:AK027264 xref: EMBL:BC131720 xref: EMBL:DQ845346 xref: HGNC:HGNC:3823 xref: UniGene:Hs.431498 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015712 ! FOXP1_HUMAN relationship: codes_for CCO:B0015721 ! A3KMG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011396 name: FOXP2_human def: "Forkhead box protein P2 gene" [UniProtKB:O15409] synonym: "CAGH44" EXACT [UniProtKB:O15409] synonym: "TNRC10" EXACT [UniProtKB:O15409] xref: EMBL:AC003992 xref: EMBL:AC020606 xref: EMBL:AC073626 xref: EMBL:AF337817 xref: EMBL:AF467252 xref: EMBL:AF467253 xref: EMBL:AF467254 xref: EMBL:AF467255 xref: EMBL:AF467256 xref: EMBL:AF467257 xref: EMBL:AF467259 xref: EMBL:AF493430 xref: EMBL:AF515031 xref: EMBL:AF515032 xref: EMBL:AF515033 xref: EMBL:AF515034 xref: EMBL:AF515035 xref: EMBL:AF515036 xref: EMBL:AF515037 xref: EMBL:AF515038 xref: EMBL:AF515039 xref: EMBL:AF515040 xref: EMBL:AF515041 xref: EMBL:AF515042 xref: EMBL:AF515043 xref: EMBL:AF515044 xref: EMBL:AF515045 xref: EMBL:AF515046 xref: EMBL:AF515047 xref: EMBL:AF515048 xref: EMBL:AF515049 xref: EMBL:AF515050 xref: EMBL:AK131266 xref: EMBL:AY144615 xref: EMBL:CH471070 xref: EMBL:U80741 xref: HGNC:HGNC:13875 xref: UniGene:Hs.656280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015701 ! Q8N6B5_HUMAN relationship: codes_for CCO:B0015717 ! FOXP2_HUMAN relationship: codes_for CCO:B0032516 ! A8MUV4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011397 name: FOXP4_human def: "Forkhead box protein P4 gene" [UniProtKB:Q8IVH2] synonym: "FKHLA" EXACT [UniProtKB:Q8IVH2] xref: EMBL:AB080747 xref: EMBL:AL139331 xref: EMBL:BC013030 xref: EMBL:BC016874 xref: EMBL:BC040962 xref: EMBL:BC052803 xref: EMBL:CH471081 xref: HGNC:HGNC:20842 xref: UniGene:Hs.131436 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015710 ! Q7Z7F8_HUMAN relationship: codes_for CCO:B0015713 ! FOXP4_HUMAN relationship: codes_for CCO:B0015715 ! Q96AP5_HUMAN relationship: codes_for CCO:B0015719 ! Q8IW55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011406 name: FZD10_human def: "Frizzled-10 precursor gene" [UniProtKB:Q9ULW2] xref: EMBL:AB027464 xref: EMBL:BC074997 xref: EMBL:BC074998 xref: HGNC:HGNC:4039 xref: UniGene:Hs.31664 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038865 ! FZD10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011407 name: FZD1_human def: "Frizzled-1 precursor gene" [UniProtKB:Q9UP38] xref: EMBL:AB017363 xref: EMBL:AC084381 xref: EMBL:AF072872 xref: EMBL:BC051271 xref: HGNC:HGNC:4038 xref: UniGene:Hs.94234 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038855 ! FZD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011408 name: FZD2_human def: "Frizzled-2 precursor gene" [UniProtKB:Q14332] xref: EMBL:AB017364 xref: EMBL:BC113402 xref: EMBL:BC113404 xref: EMBL:L37882 xref: HGNC:HGNC:4040 xref: UniGene:Hs.142912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038857 ! FZD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011409 name: FZD5_human def: "Frizzled-5 precursor gene" [UniProtKB:Q13467] synonym: "HFZ5" EXACT [UniProtKB:Q13467] xref: EMBL:AB043702 xref: EMBL:AC096772 xref: EMBL:U43318 xref: HGNC:HGNC:4043 xref: UniGene:Hs.17631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038854 ! FZD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011410 name: FZD7_human def: "Frizzled-7 precursor gene" [UniProtKB:O75084] xref: EMBL:AB010881 xref: EMBL:AB017365 xref: EMBL:BC015915 xref: HGNC:HGNC:4045 xref: UniGene:Hs.173859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038856 ! FZD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011411 name: FZD8_human def: "Frizzled-8 precursor gene" [UniProtKB:Q9H461] xref: EMBL:AB043703 xref: EMBL:AL121749 xref: HGNC:HGNC:4046 xref: UniGene:Hs.302634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038863 ! FZD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011412 name: FZD9_human def: "Frizzled-9 precursor gene" [UniProtKB:O00144] synonym: "FZD3" EXACT [UniProtKB:O00144] xref: EMBL:AC005049 xref: EMBL:BC026333 xref: EMBL:U82169 xref: HGNC:HGNC:4047 xref: UniGene:Hs.647029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038861 ! FZD9_HUMAN relationship: codes_for CCO:B0038866 ! Q8TAN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011416 name: GABRA1_human def: "Gamma-aminobutyric acid receptor subunit alpha-1 precursor gene" [UniProtKB:P14867] xref: EMBL:BC030696 xref: EMBL:X13584 xref: EMBL:X14766 xref: HGNC:HGNC:4075 xref: UniGene:Hs.175934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022914 ! GBRA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011417 name: GABRA2_human def: "Gamma-aminobutyric acid receptor subunit alpha-2 precursor gene" [UniProtKB:P47869] xref: EMBL:AB209295 xref: EMBL:S62907 xref: HGNC:HGNC:4076 xref: UniGene:Hs.116250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022924 ! GBRA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011418 name: GABRA3_human def: "Gamma-aminobutyric acid receptor subunit alpha-3 precursor gene" [UniProtKB:P34903] xref: EMBL:AF165901 xref: EMBL:AF165902 xref: EMBL:AF165903 xref: EMBL:AF165904 xref: EMBL:AF165905 xref: EMBL:AF165906 xref: EMBL:AF166359 xref: EMBL:AF166360 xref: EMBL:AF166361 xref: EMBL:BC028629 xref: EMBL:S62908 xref: HGNC:HGNC:4077 xref: UniGene:Hs.123024 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022933 ! GBRA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011419 name: GABRA4_human def: "Gamma-aminobutyric acid receptor subunit alpha-4 precursor gene" [UniProtKB:P48169] xref: EMBL:AC107383 xref: EMBL:AK090780 xref: EMBL:BC035055 xref: EMBL:CH471069 xref: EMBL:U20166 xref: EMBL:U30461 xref: HGNC:HGNC:4078 xref: UniGene:Hs.248112 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022898 ! GBRA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011420 name: GABRA5_human def: "Gamma-aminobutyric acid receptor subunit alpha-5 precursor gene" [UniProtKB:P31644] xref: EMBL:AF061785 xref: EMBL:AF228447 xref: EMBL:AF228448 xref: EMBL:AF228449 xref: EMBL:BC111979 xref: EMBL:BC113422 xref: EMBL:BT009830 xref: EMBL:L08485 xref: HGNC:HGNC:4079 xref: UniGene:Hs.612087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022915 ! GBRA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011421 name: GABRA6_human def: "Gamma-aminobutyric acid receptor subunit alpha-6 precursor gene" [UniProtKB:Q16445] xref: EMBL:BC096241 xref: EMBL:BC096242 xref: EMBL:BC099640 xref: EMBL:BC099641 xref: EMBL:S81944 xref: HGNC:HGNC:4080 xref: UniGene:Hs.90791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022907 ! GBRA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011422 name: GABRB1_human def: "Gamma-aminobutyric acid receptor subunit beta-1 precursor gene" [UniProtKB:P18505] xref: EMBL:BC022449 xref: EMBL:M59212 xref: EMBL:M59214 xref: EMBL:M59215 xref: EMBL:M59216 xref: EMBL:S70733 xref: EMBL:X14767 xref: HGNC:HGNC:4081 xref: UniGene:Hs.27283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039239 ! GBRB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011423 name: GABRB2_human def: "Gamma-aminobutyric acid receptor subunit beta-2 precursor gene" [UniProtKB:P47870] xref: EMBL:BC099705 xref: EMBL:BC099719 xref: EMBL:BC105639 xref: EMBL:S67368 xref: EMBL:S77553 xref: EMBL:S77554 xref: HGNC:HGNC:4082 xref: UniGene:Hs.303527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039233 ! GBRB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011424 name: GABRB3_human def: "Gamma-aminobutyric acid receptor subunit beta-3 precursor gene" [UniProtKB:P28472] xref: EMBL:BC010641 xref: EMBL:L04311 xref: EMBL:M82919 xref: HGNC:HGNC:4083 xref: UniGene:Hs.302352 xref: UniGene:Hs.657298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039240 ! GBRB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011425 name: GABRD_human def: "Gamma-aminobutyric acid receptor subunit delta precursor gene" [UniProtKB:O14764] xref: EMBL:AF016917 xref: EMBL:AL391845 xref: EMBL:BC033801 xref: HGNC:HGNC:4084 xref: UniGene:Hs.113882 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022931 ! GBRD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011426 name: GABRE_human def: "Gamma-aminobutyric acid receptor subunit epsilon precursor gene" [UniProtKB:P78334] xref: EMBL:U66661 xref: EMBL:U92281 xref: EMBL:U92282 xref: EMBL:U92283 xref: EMBL:Y07637 xref: EMBL:Y09763 xref: EMBL:Y09764 xref: EMBL:Y09765 xref: HGNC:HGNC:4085 xref: UniGene:Hs.22785 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022901 ! GBRE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011427 name: GABRG1_human def: "Gamma-aminobutyric acid receptor subunit gamma-1 precursor gene" [UniProtKB:Q8N1C3] xref: EMBL:AK122845 xref: EMBL:BC031087 xref: EMBL:CH471069 xref: EMBL:CR933628 xref: HGNC:HGNC:4086 xref: UniGene:Hs.375051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022906 ! GBRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011428 name: GABRG2_human def: "Gamma-aminobutyric acid receptor subunit gamma-2 precursor gene" [UniProtKB:P18507] xref: EMBL:AC008611 xref: EMBL:AF165124 xref: EMBL:BC059389 xref: EMBL:BC069348 xref: EMBL:BC074795 xref: EMBL:X15376 xref: HGNC:HGNC:4087 xref: UniGene:Hs.7195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022909 ! GBRG2_HUMAN relationship: codes_for CCO:B0022935 ! Q6PCC3_HUMAN relationship: codes_for CCO:B0027056 ! A8MWU7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011429 name: GABRG3_human def: "Gamma-aminobutyric acid receptor subunit gamma-3 precursor gene" [UniProtKB:Q99928] xref: EMBL:AF228450 xref: EMBL:AF228451 xref: EMBL:AF228452 xref: EMBL:AF228453 xref: EMBL:AF228454 xref: EMBL:AF228455 xref: EMBL:AF228456 xref: EMBL:AF228457 xref: EMBL:AF228458 xref: EMBL:AF269135 xref: EMBL:AF269136 xref: EMBL:AF269137 xref: EMBL:AF269138 xref: EMBL:AF269139 xref: EMBL:AF269140 xref: EMBL:AF269141 xref: EMBL:AF269142 xref: EMBL:AF269143 xref: EMBL:AF269144 xref: EMBL:S82769 xref: HGNC:HGNC:4088 xref: UniGene:Hs.569475 xref: UniGene:Hs.592027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022900 ! GBRG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011431 name: GABRR1_human def: "Gamma-aminobutyric acid receptor subunit rho-1 precursor gene" [UniProtKB:P24046] xref: EMBL:AL353135 xref: EMBL:AL353659 xref: EMBL:M62400 xref: HGNC:HGNC:4090 xref: UniGene:Hs.437745 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022926 ! GBRR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011432 name: GABRR2_human def: "Gamma-aminobutyric acid receptor subunit rho-2 precursor gene" [UniProtKB:P28476] xref: EMBL:AL121833 xref: EMBL:BC130352 xref: EMBL:BC130354 xref: EMBL:M86868 xref: HGNC:HGNC:4091 xref: UniGene:Hs.99927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022899 ! GBRR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011433 name: GABRQ_human def: "Gamma-aminobutyric acid receptor subunit theta precursor gene" [UniProtKB:Q9UN88] xref: EMBL:AF144648 xref: EMBL:AF189259 xref: EMBL:BC109210 xref: EMBL:BC109211 xref: HGNC:HGNC:14454 xref: UniGene:Hs.283081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022903 ! GBRT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011434 name: GBX1_human def: "Homeobox protein GBX-1 gene" [UniProtKB:Q14549] xref: EMBL:AC010973 xref: EMBL:L11239 xref: HGNC:HGNC:4185 xref: UniGene:Hs.647114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036796 ! GBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011435 name: GBX2_human def: "Homeobox protein GBX-2 gene" [UniProtKB:P52951] xref: EMBL:AC079135 xref: EMBL:AF118452 xref: EMBL:U02080 xref: EMBL:U31468 xref: HGNC:HGNC:4186 xref: UniGene:Hs.184945 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036788 ! GBX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011437 name: GLRA1_human def: "Glycine receptor subunit alpha-1 precursor gene" [UniProtKB:P23415] xref: EMBL:BC074980 xref: EMBL:BC114947 xref: EMBL:X52009 xref: HGNC:HGNC:4326 xref: UniGene:Hs.121490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022913 ! GLRA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011438 name: GLRA2_human def: "Glycine receptor subunit alpha-2 precursor gene" [UniProtKB:P23416] xref: EMBL:AF053487 xref: EMBL:AF053488 xref: EMBL:AF053489 xref: EMBL:AF053490 xref: EMBL:AF053491 xref: EMBL:AF053492 xref: EMBL:AF053493 xref: EMBL:AF053494 xref: EMBL:AF053495 xref: EMBL:AY437083 xref: EMBL:AY437084 xref: EMBL:BC032864 xref: EMBL:CR450343 xref: EMBL:U77724 xref: EMBL:U77725 xref: EMBL:U77726 xref: EMBL:U77727 xref: EMBL:U77728 xref: EMBL:U77729 xref: EMBL:U77730 xref: EMBL:U77731 xref: EMBL:X52008 xref: HGNC:HGNC:4327 xref: UniGene:Hs.2700 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022917 ! GLRA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011440 name: GLRB_human def: "Glycine receptor subunit beta precursor gene" [UniProtKB:P48167] xref: EMBL:AF094754 xref: EMBL:AF094755 xref: EMBL:BC032635 xref: EMBL:U33267 xref: HGNC:HGNC:4329 xref: UniGene:Hs.32973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022911 ! GLRB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011444 name: GSTM1_human def: "Glutathione S-transferase Mu 1 gene" [UniProtKB:P09488] synonym: "GST1" EXACT [UniProtKB:P09488] xref: EMBL:AY510272 xref: EMBL:AY532926 xref: EMBL:CR541868 xref: EMBL:J03817 xref: EMBL:X08020 xref: EMBL:X51451 xref: EMBL:X68676 xref: HGNC:HGNC:4632 xref: UniGene:Hs.301961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038241 ! GSTM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011446 name: GSTM3_human def: "Glutathione S-transferase Mu 3 gene" [UniProtKB:P21266] synonym: "GST5" EXACT [UniProtKB:P21266] xref: EMBL:AF043105 xref: EMBL:BC000088 xref: EMBL:BC008790 xref: EMBL:BT019945 xref: EMBL:J05459 xref: HGNC:HGNC:4635 xref: UniGene:Hs.2006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038221 ! GSTM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011448 name: GSTO1_human def: "Glutathione S-transferase omega-1 gene" [UniProtKB:P78417] synonym: "GSTTLP28" EXACT [UniProtKB:P78417] xref: EMBL:AF212303 xref: EMBL:AL139341 xref: EMBL:AY817669 xref: EMBL:BC000127 xref: EMBL:BX537431 xref: EMBL:U90313 xref: HGNC:HGNC:13312 xref: UniGene:Hs.190028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036172 ! GSTO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011450 name: GSX1_human def: "GS homeobox 1 gene" [UniProtKB:Q9H4S2] synonym: "GSH1" EXACT [UniProtKB:Q9H4S2] xref: EMBL:AB044157 xref: EMBL:AB044158 xref: EMBL:AL390738 xref: HGNC:HGNC:20374 xref: UniGene:Hs.351785 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036810 ! GSX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011451 name: GSX2_human def: "GS homeobox 2 gene" [UniProtKB:Q9BZM3] synonym: "GSH2" EXACT [UniProtKB:Q9BZM3] xref: EMBL:AB028838 xref: EMBL:AF306343 xref: EMBL:AF306344 xref: EMBL:AF439445 xref: EMBL:BC075089 xref: EMBL:BC075090 xref: HGNC:HGNC:24959 xref: UniGene:Hs.371899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036832 ! GSX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011453 name: HABP4_human def: "Intracellular hyaluronan-binding protein 4 gene" [UniProtKB:Q5JVS0] xref: EMBL:AF241831 xref: EMBL:AL133477 xref: EMBL:BC018788 xref: EMBL:U77327 xref: HGNC:HGNC:17062 xref: UniGene:Hs.494567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037756 ! HABP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011455 name: HCFC2_human def: "Host cell factor 2 gene" [UniProtKB:Q9Y5Z7] xref: EMBL:AF117210 xref: EMBL:BC033799 xref: HGNC:HGNC:24972 xref: UniGene:Hs.506558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036469 ! HCFC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011459 name: HILS1_human def: "Spermatid-specific linker histone H1-like protein gene" [UniProtKB:P60008] xref: EMBL:AY286318 xref: HGNC:HGNC:30616 xref: UniGene:Hs.25934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036287 ! HILS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011462 name: HPRT1_human def: "Hypoxanthine-guanine phosphoribosyltransferase gene" [UniProtKB:P00492] synonym: "HPRT" EXACT [UniProtKB:P00492] xref: EMBL:AC004383 xref: EMBL:AY780550 xref: EMBL:BC000578 xref: EMBL:BT019350 xref: EMBL:CH471107 xref: EMBL:L29382 xref: EMBL:L29383 xref: EMBL:M12452 xref: EMBL:M26434 xref: EMBL:M31642 xref: EMBL:S60300 xref: EMBL:S79313 xref: HGNC:HGNC:5157 xref: UniGene:Hs.412707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036957 ! HPRT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011463 name: HRH2_human def: "Histamine H2 receptor gene" [UniProtKB:P25021] xref: EMBL:AB023486 xref: EMBL:AB041384 xref: EMBL:AY136744 xref: EMBL:D49783 xref: EMBL:M64799 xref: EMBL:X98133 xref: HGNC:HGNC:5183 xref: UniGene:Hs.247885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038262 ! HRH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011464 name: HOXA4_human def: "Homeobox protein Hox-A4 gene" [UniProtKB:Q00056] synonym: "HOX1D" EXACT [UniProtKB:Q00056] xref: EMBL:AC004080 xref: EMBL:BC126994 xref: EMBL:M28199 xref: EMBL:M74297 xref: HGNC:HGNC:5105 xref: UniGene:Hs.533357 xref: UniGene:Hs.654466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036825 ! HXA4_HUMAN relationship: codes_for CCO:B0036831 ! A1L0T6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011465 name: HOXA5_human def: "Homeobox protein Hox-A5 gene" [UniProtKB:P20719] synonym: "HOX1C" EXACT [UniProtKB:P20719] xref: EMBL:AC004080 xref: EMBL:BC013682 xref: EMBL:BT009744 xref: EMBL:CR542256 xref: EMBL:M26679 xref: HGNC:HGNC:5106 xref: UniGene:Hs.655218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036801 ! HXA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011466 name: HOXA6_human def: "Homeobox protein Hox-A6 gene" [UniProtKB:P31267] synonym: "HOX1B" EXACT [UniProtKB:P31267] xref: EMBL:AC004080 xref: EMBL:BC069497 xref: EMBL:BC104915 xref: EMBL:BC104917 xref: HGNC:HGNC:5107 xref: UniGene:Hs.679517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036814 ! HXA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011467 name: HOXA7_human def: "Homeobox protein Hox-A7 gene" [UniProtKB:P31268] synonym: "HOX1A" EXACT [UniProtKB:P31268] xref: EMBL:AC004080 xref: EMBL:AF026397 xref: EMBL:AF032095 xref: EMBL:AJ005814 xref: EMBL:U92543 xref: EMBL:X84803 xref: EMBL:X84804 xref: HGNC:HGNC:5108 xref: UniGene:Hs.660918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036793 ! HXA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011468 name: HOXB4_human def: "Homeobox protein Hox-B4 gene" [UniProtKB:P17483] synonym: "HOX2F" EXACT [UniProtKB:P17483] xref: EMBL:AF287967 xref: EMBL:AF307160 xref: EMBL:AL137449 xref: EMBL:BC049204 xref: EMBL:X16174 xref: HGNC:HGNC:5115 xref: UniGene:Hs.664706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036797 ! HXB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011469 name: HOXB5_human def: "Homeobox protein Hox-B5 gene" [UniProtKB:P09067] synonym: "HOX2A" EXACT [UniProtKB:P09067] xref: EMBL:AF287967 xref: EMBL:BC117247 xref: EMBL:K02572 xref: EMBL:M86726 xref: EMBL:M92299 xref: EMBL:X03794 xref: HGNC:HGNC:5116 xref: UniGene:Hs.654456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036790 ! HXB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011470 name: HOXB6_human def: "Homeobox protein Hox-B6 gene" [UniProtKB:P17509] synonym: "HOX2B" EXACT [UniProtKB:P17509] xref: EMBL:AF287967 xref: EMBL:AJ270993 xref: EMBL:BC014651 xref: EMBL:K02571 xref: EMBL:M30597 xref: EMBL:X58431 xref: HGNC:HGNC:5117 xref: UniGene:Hs.98428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036826 ! HXB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011471 name: HOXB7_human def: "Homeobox protein Hox-B7 gene" [UniProtKB:P09629] synonym: "HOX2C" EXACT [UniProtKB:P09629] xref: EMBL:M16937 xref: EMBL:M30598 xref: EMBL:S49765 xref: HGNC:HGNC:5118 xref: UniGene:Hs.436181 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036799 ! HXB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011472 name: HOXB8_human def: "Homeobox protein Hox-B8 gene" [UniProtKB:P17481] synonym: "HOX2D" EXACT [UniProtKB:P17481] xref: EMBL:AY014293 xref: EMBL:AY014294 xref: EMBL:X16173 xref: HGNC:HGNC:5119 xref: UniGene:Hs.514292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036789 ! HXB8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011473 name: HOXB9_human def: "Homeobox protein Hox-B9 gene" [UniProtKB:P17482] synonym: "HOX2E" EXACT [UniProtKB:P17482] xref: EMBL:AY014295 xref: EMBL:AY014296 xref: EMBL:BC015565 xref: EMBL:X16172 xref: HGNC:HGNC:5120 xref: UniGene:Hs.463350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036838 ! HXB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011474 name: HOXC4_human def: "Homeobox protein Hox-C4 gene" [UniProtKB:P09017] synonym: "HOX3E" EXACT [UniProtKB:P09017] xref: EMBL:AY014297 xref: EMBL:AY014298 xref: EMBL:BC050442 xref: EMBL:X07495 xref: HGNC:HGNC:5126 xref: UniGene:Hs.549040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036808 ! Q86TF7_HUMAN relationship: codes_for CCO:B0036816 ! HXC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011475 name: HOXC5_human def: "Homeobox protein Hox-C5 gene" [UniProtKB:Q00444] synonym: "HOX3D" EXACT [UniProtKB:Q00444] xref: EMBL:X61755 xref: HGNC:HGNC:5127 xref: UniGene:Hs.549040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036813 ! HXC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011476 name: HOXC6_human def: "Homeobox protein Hox-C6 gene" [UniProtKB:P09630] synonym: "HOX3C" EXACT [UniProtKB:P09630] xref: EMBL:BC074844 xref: EMBL:BC074845 xref: EMBL:M16938 xref: EMBL:S82986 xref: HGNC:HGNC:5128 xref: UniGene:Hs.549040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036818 ! HXC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011477 name: HOXC8_human def: "Homeobox protein Hox-C8 gene" [UniProtKB:P31273] synonym: "HOX3A" EXACT [UniProtKB:P31273] xref: EMBL:AY014299 xref: EMBL:AY014300 xref: EMBL:BC053898 xref: EMBL:X99680 xref: EMBL:X99681 xref: HGNC:HGNC:5129 xref: UniGene:Hs.664500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036827 ! HXC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011478 name: HOXD4_human def: "Homeobox protein Hox-D4 gene" [UniProtKB:P09016] synonym: "HOX4B" EXACT [UniProtKB:P09016] xref: EMBL:BC016763 xref: EMBL:BC074797 xref: EMBL:X04706 xref: EMBL:X17360 xref: HGNC:HGNC:5138 xref: UniGene:Hs.591609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036792 ! HXD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011479 name: HOXD8_human def: "Homeobox protein Hox-D8 gene" [UniProtKB:P13378] synonym: "HOX4E" EXACT [UniProtKB:P13378] xref: EMBL:AC009336 xref: EMBL:AY014303 xref: EMBL:AY014304 xref: EMBL:X15507 xref: HGNC:HGNC:5139 xref: UniGene:Hs.301963 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036821 ! HXD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011480 name: HOXD9_human def: "Homeobox protein Hox-D9 gene" [UniProtKB:P28356] synonym: "HOX4C" EXACT [UniProtKB:P28356] xref: EMBL:AC009336 xref: EMBL:BC044855 xref: EMBL:X15506 xref: EMBL:X59372 xref: HGNC:HGNC:5140 xref: UniGene:Hs.701987 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036828 ! HXD9_HUMAN relationship: codes_for CCO:B0036830 ! A8MYQ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011482 name: EIF4E_human def: "Eukaryotic translation initiation factor 4E gene" [UniProtKB:P06730] synonym: "EIF4EL1" EXACT [UniProtKB:P06730] synonym: "EIF4F" EXACT [UniProtKB:P06730] xref: EMBL:BC012611 xref: EMBL:BC035166 xref: EMBL:BC043226 xref: EMBL:M15353 xref: HGNC:HGNC:3287 xref: UniGene:Hs.249718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016186 ! IF4E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011483 name: EIF5A_human def: "Eukaryotic translation initiation factor 5A-1 gene" [UniProtKB:P63241] xref: EMBL:AY129319 xref: EMBL:AY129320 xref: EMBL:AY129321 xref: EMBL:AY129322 xref: EMBL:BC000751 xref: EMBL:BC001832 xref: EMBL:BC030160 xref: EMBL:BC080196 xref: EMBL:BC085015 xref: EMBL:BC107779 xref: EMBL:M23419 xref: EMBL:S72024 xref: EMBL:U17969 xref: HGNC:HGNC:3300 xref: UniGene:Hs.534314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036567 ! IF5A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011484 name: EIF5A2_human def: "Eukaryotic translation initiation factor 5A-2 gene" [UniProtKB:Q9GZV4] xref: EMBL:AF262027 xref: EMBL:AF293386 xref: EMBL:AF293387 xref: EMBL:AY205258 xref: EMBL:AY205259 xref: EMBL:AY205260 xref: EMBL:AY205261 xref: EMBL:BC036072 xref: HGNC:HGNC:3301 xref: UniGene:Hs.164144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036577 ! IF5A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011485 name: IFNB1_human def: "Interferon beta precursor gene" [UniProtKB:P01574] synonym: "IFB" EXACT [UniProtKB:P01574] synonym: "IFNB" EXACT [UniProtKB:P01574] xref: EMBL:BC069314 xref: EMBL:M28622 xref: EMBL:V00534 xref: EMBL:V00535 xref: EMBL:V00546 xref: EMBL:V00547 xref: HGNC:HGNC:5434 xref: UniGene:Hs.93177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015966 ! IFNB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011486 name: IKZF2_human def: "Zinc finger protein Helios gene" [UniProtKB:Q9UKS7] synonym: "HELIOS" EXACT [UniProtKB:Q9UKS7] synonym: "ZNFN1A2" EXACT [UniProtKB:Q9UKS7] xref: EMBL:AF130863 xref: EMBL:BC028936 xref: HGNC:HGNC:13177 xref: UniGene:Hs.604950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021859 ! IKZF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011487 name: IKZF4_human def: "Zinc finger protein Eos gene" [UniProtKB:Q9H2S9] synonym: "KIAA1782" EXACT [UniProtKB:Q9H2S9] synonym: "ZNFN1A4" EXACT [UniProtKB:Q9H2S9] xref: EMBL:AB058685 xref: EMBL:AF230809 xref: EMBL:BX647761 xref: HGNC:HGNC:13179 xref: UniGene:Hs.553221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021866 ! IKZF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011488 name: KPNA1_human def: "Importin subunit alpha-1 gene" [UniProtKB:P52294] synonym: "RCH2" EXACT [UniProtKB:P52294] xref: EMBL:BC002374 xref: EMBL:BC003009 xref: EMBL:BT006959 xref: EMBL:S75295 xref: HGNC:HGNC:6394 xref: UniGene:Hs.161008 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020532 ! IMA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011489 name: KPNA6_human def: "Importin subunit alpha-7 gene" [UniProtKB:O60684] synonym: "IPOA7" EXACT [UniProtKB:O60684] xref: EMBL:AF060543 xref: EMBL:AL049795 xref: EMBL:AL445248 xref: EMBL:BC020520 xref: EMBL:BT009843 xref: EMBL:CH471059 xref: HGNC:HGNC:6399 xref: UniGene:Hs.470588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020529 ! IMA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011490 name: INHBB_human def: "Inhibin beta B chain precursor gene" [UniProtKB:P09529] xref: EMBL:BC030029 xref: EMBL:M13437 xref: EMBL:M31668 xref: EMBL:M31669 xref: EMBL:M31682 xref: HGNC:HGNC:6067 xref: UniGene:Hs.1735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039075 ! INHBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011492 name: IRF5_human def: "Interferon regulatory factor 5 gene" [UniProtKB:Q13568] xref: EMBL:AY504946 xref: EMBL:AY504947 xref: EMBL:AY693665 xref: EMBL:BC004139 xref: EMBL:BC004201 xref: EMBL:CH236950 xref: EMBL:CH471070 xref: EMBL:DQ277633 xref: EMBL:DQ277634 xref: EMBL:EF064718 xref: EMBL:U51127 xref: HGNC:HGNC:6120 xref: UniGene:Hs.521181 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037921 ! Q6RCM8_HUMAN relationship: codes_for CCO:B0037924 ! IRF5_HUMAN relationship: codes_for CCO:B0037930 ! Q1A7B4_HUMAN relationship: codes_for CCO:B0037933 ! Q64GB2_HUMAN relationship: codes_for CCO:B0037937 ! A4D1J8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011493 name: IRF6_human def: "Interferon regulatory factor 6 gene" [UniProtKB:O14896] xref: EMBL:AF027292 xref: EMBL:AL022398 xref: EMBL:BC014852 xref: HGNC:HGNC:6121 xref: UniGene:Hs.591415 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037936 ! IRF6_HUMAN relationship: codes_for CCO:B0054220 ! B1AJU4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011494 name: IRF7_human def: "Interferon regulatory factor 7 gene" [UniProtKB:Q92985] xref: EMBL:AF076494 xref: EMBL:U53830 xref: EMBL:U53831 xref: EMBL:U53832 xref: EMBL:U73036 xref: HGNC:HGNC:6122 xref: UniGene:Hs.166120 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037928 ! IRF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011495 name: IRF8_human def: "Interferon regulatory factor 8 gene" [UniProtKB:Q02556] synonym: "ICSBP1" EXACT [UniProtKB:Q02556] xref: EMBL:BC126247 xref: EMBL:M91196 xref: HGNC:HGNC:5358 xref: UniGene:Hs.137427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037929 ! IRF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011496 name: IRF9_human def: "Interferon regulatory factor 9 gene" [UniProtKB:Q00978] synonym: "ISGF3G" EXACT [UniProtKB:Q00978] xref: EMBL:BC035716 xref: EMBL:M87503 xref: HGNC:HGNC:6131 xref: UniGene:Hs.1706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037934 ! IRF9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011497 name: JAG1_human def: "Protein jagged-1 precursor gene" [UniProtKB:P78504] synonym: "JAGL1" EXACT [UniProtKB:P78504] xref: EMBL:AF003837 xref: EMBL:AF028593 xref: EMBL:AL035456 xref: EMBL:BC126205 xref: EMBL:BC126207 xref: EMBL:U61276 xref: EMBL:U73936 xref: EMBL:U77720 xref: HGNC:HGNC:6188 xref: UniGene:Hs.224012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028290 ! JAG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011499 name: KIAA0415_human def: "KIAA0415 gene product gene" [UniProtKB:A4D1Z4] synonym: "tcag7.1310" EXACT [UniProtKB:A4D1Z4] xref: EMBL:CH236953 xref: UniGene:Hs.558440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036929 ! A4D1Z4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011500 name: KIAA1967_human def: "Protein KIAA1967 gene" [UniProtKB:Q8N163] synonym: "DBC1" EXACT [UniProtKB:Q8N163] xref: EMBL:AB075847 xref: EMBL:AC037459 xref: EMBL:AF293335 xref: EMBL:AK022661 xref: EMBL:AK096547 xref: EMBL:AL137523 xref: EMBL:AL834162 xref: EMBL:AL834351 xref: EMBL:AL834352 xref: EMBL:BC018269 xref: EMBL:BC065495 xref: EMBL:BX640952 xref: EMBL:CH471080 xref: HGNC:HGNC:23360 xref: UniGene:Hs.654720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038243 ! K1967_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011514 name: PPFIBP2_human def: "Liprin-beta-2 gene" [UniProtKB:Q8ND30] xref: EMBL:AF034803 xref: EMBL:AL834426 xref: EMBL:BC021714 xref: HGNC:HGNC:9250 xref: UniGene:Hs.655714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037978 ! LIPB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011517 name: LRRN2_human def: "Leucine-rich repeat neuronal protein 2 precursor gene" [UniProtKB:O75325] synonym: "GAC1" EXACT [UniProtKB:O75325] synonym: "LRRN5" EXACT [UniProtKB:O75325] synonym: "UNQ256/PRO293" EXACT [UniProtKB:O75325] xref: EMBL:AF030435 xref: EMBL:AL512306 xref: EMBL:AY358290 xref: EMBL:BC034047 xref: EMBL:BC068541 xref: HGNC:HGNC:16914 xref: UniGene:Hs.26312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036631 ! LRRN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011521 name: MAP3K7_human def: "Mitogen-activated protein kinase kinase kinase 7 gene" [UniProtKB:O43318] synonym: "TAK1" EXACT [UniProtKB:O43318] xref: EMBL:AB009356 xref: EMBL:AB009357 xref: EMBL:AB009358 xref: EMBL:AL121837 xref: EMBL:AL121964 xref: EMBL:BC017715 xref: EMBL:DQ314875 xref: HGNC:HGNC:6859 xref: UniGene:Hs.644143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038746 ! M3K7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011522 name: MAP3K9_human def: "Mitogen-activated protein kinase kinase kinase 9 gene" [UniProtKB:P80192] synonym: "MLK1" EXACT [UniProtKB:P80192] synonym: "PRKE1" EXACT [UniProtKB:P80192] xref: EMBL:AF251442 xref: EMBL:AY327900 xref: EMBL:BC111407 xref: HGNC:HGNC:6861 xref: UniGene:Hs.445496 xref: UniGene:Hs.593542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038544 ! M3K9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011526 name: MARK1_human def: "Serine/threonine-protein kinase MARK1 gene" [UniProtKB:Q9P0L2] synonym: "KIAA1477" EXACT [UniProtKB:Q9P0L2] synonym: "MARK" EXACT [UniProtKB:Q9P0L2] xref: EMBL:AB040910 xref: EMBL:AC096640 xref: EMBL:AF154845 xref: EMBL:AK027493 xref: EMBL:AL592406 xref: EMBL:BC113869 xref: EMBL:BC114478 xref: HGNC:HGNC:6896 xref: UniGene:Hs.497806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037393 ! MARK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011527 name: MARK2_human def: "Serine/threonine-protein kinase MARK2 gene" [UniProtKB:Q7KZI7] synonym: "EMK1" EXACT [UniProtKB:Q7KZI7] xref: EMBL:AB188493 xref: EMBL:AF387638 xref: EMBL:BC008771 xref: EMBL:BC084540 xref: EMBL:BT007342 xref: EMBL:U73647 xref: EMBL:X97630 xref: EMBL:Z25427 xref: HGNC:HGNC:3332 xref: UniGene:Hs.567261 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037391 ! MARK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011528 name: MAST1_human def: "Microtubule-associated serine/threonine-protein kinase 1 gene" [UniProtKB:Q9Y2H9] synonym: "KIAA0973" EXACT [UniProtKB:Q9Y2H9] xref: EMBL:AB023190 xref: EMBL:AC020934 xref: EMBL:AD000092 xref: EMBL:BC027985 xref: HGNC:HGNC:19034 xref: UniGene:Hs.227489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036609 ! MAST1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011531 name: MED12L_human def: "Mediator of RNA polymerase II transcription subunit 12-like protein gene" [UniProtKB:Q86YW9] synonym: "KIAA1635" EXACT [UniProtKB:Q86YW9] synonym: "PRO0314" EXACT [UniProtKB:Q86YW9] synonym: "TNRC11L" EXACT [UniProtKB:Q86YW9] synonym: "TRALP" EXACT [UniProtKB:Q86YW9] synonym: "TRALPUSH" EXACT [UniProtKB:Q86YW9] xref: EMBL:AB046855 xref: EMBL:AF090917 xref: EMBL:AF388364 xref: EMBL:AF388365 xref: EMBL:AF399708 xref: EMBL:AK022714 xref: EMBL:CH471052 xref: HGNC:HGNC:16050 xref: UniGene:Hs.58561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038407 ! MD12L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011538 name: MNX1_human def: "Motor neuron and pancreas homeobox protein 1 gene" [UniProtKB:P50219] synonym: "HLXB9" EXACT [UniProtKB:P50219] xref: EMBL:AF107452 xref: EMBL:AF107453 xref: EMBL:U07663 xref: EMBL:U07664 xref: HGNC:HGNC:4979 xref: UniGene:Hs.37035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036823 ! MNX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011541 name: MAP2K3_human def: "Dual specificity mitogen-activated protein kinase kinase 3 gene" [UniProtKB:P46734] synonym: "MEK3" EXACT [UniProtKB:P46734] synonym: "MKK3" EXACT [UniProtKB:P46734] synonym: "PRKMK3" EXACT [UniProtKB:P46734] xref: EMBL:BC032478 xref: EMBL:D87116 xref: EMBL:L36719 xref: EMBL:U66839 xref: EMBL:U66840 xref: HGNC:HGNC:6843 xref: UniGene:Hs.514012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020948 ! MP2K3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011542 name: MAP2K4_human def: "Dual specificity mitogen-activated protein kinase kinase 4 gene" [UniProtKB:P45985] synonym: "JNKK1" EXACT [UniProtKB:P45985] synonym: "MKK4" EXACT [UniProtKB:P45985] synonym: "PRKMK4" EXACT [UniProtKB:P45985] synonym: "SERK1" EXACT [UniProtKB:P45985] xref: EMBL:AF070080 xref: EMBL:AF070081 xref: EMBL:AF070082 xref: EMBL:AF070083 xref: EMBL:AF070084 xref: EMBL:AF070085 xref: EMBL:AF070086 xref: EMBL:AF070087 xref: EMBL:AF070088 xref: EMBL:AF070089 xref: EMBL:AF070090 xref: EMBL:BT019676 xref: EMBL:DQ015703 xref: EMBL:L36870 xref: EMBL:U17743 xref: HGNC:HGNC:6844 xref: UniGene:Hs.514681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038116 ! MP2K4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011543 name: MAP2K7_human def: "Dual specificity mitogen-activated protein kinase kinase 7 gene" [UniProtKB:O14733] synonym: "JNKK2" EXACT [UniProtKB:O14733] synonym: "MEK7" EXACT [UniProtKB:O14733] synonym: "MKK7" EXACT [UniProtKB:O14733] synonym: "PRKMK7" EXACT [UniProtKB:O14733] xref: EMBL:AF003199 xref: EMBL:AF006689 xref: EMBL:AF013588 xref: EMBL:AF013589 xref: EMBL:AF014401 xref: EMBL:AF022805 xref: EMBL:BC038295 xref: EMBL:DQ445915 xref: HGNC:HGNC:6847 xref: UniGene:Hs.531754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020951 ! MP2K7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011547 name: MTSS1L_human def: "MTSS1-like protein gene" [UniProtKB:Q765P7] xref: EMBL:AB115770 xref: EMBL:AC020763 xref: EMBL:BC002770 xref: UniGene:Hs.432387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039174 ! MTSSL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011548 name: MYLK2_human def: "Myosin light chain kinase 2, skeletal/cardiac muscle gene" [UniProtKB:Q9H1R3] xref: EMBL:AF325549 xref: EMBL:AJ272502 xref: EMBL:AL160175 xref: EMBL:BC007753 xref: EMBL:BC069627 xref: EMBL:BC092413 xref: EMBL:BC127622 xref: HGNC:HGNC:16243 xref: UniGene:Hs.86092 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036526 ! MYLK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011550 name: MYLK_human def: "Myosin light chain kinase, smooth muscle gene" [UniProtKB:Q15746] synonym: "MLCK" EXACT [UniProtKB:Q15746] xref: EMBL:AB037663 xref: EMBL:AF069601 xref: EMBL:AF069602 xref: EMBL:AF069603 xref: EMBL:AF069604 xref: EMBL:AF096766 xref: EMBL:AF096767 xref: EMBL:AF096768 xref: EMBL:AF096769 xref: EMBL:AF096770 xref: EMBL:AF096771 xref: EMBL:AF096774 xref: EMBL:AY339601 xref: EMBL:AY424269 xref: EMBL:AY424270 xref: EMBL:U48959 xref: EMBL:X85337 xref: EMBL:X90870 xref: HGNC:HGNC:7590 xref: UniGene:Hs.556600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036528 ! MYLK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011551 name: MYO9B_human def: "Myosin-IXb gene" [UniProtKB:Q13459] synonym: "MYR5" EXACT [UniProtKB:Q13459] xref: EMBL:AF020267 xref: EMBL:AF143684 xref: EMBL:AK002201 xref: EMBL:U42391 xref: HGNC:HGNC:7609 xref: UniGene:Hs.123198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031122 ! MYO9B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011555 name: NAT10_human def: "N-acetyltransferase 10 gene" [UniProtKB:Q9H0A0] synonym: "ALP" EXACT [UniProtKB:Q9H0A0] synonym: "KIAA1709" EXACT [UniProtKB:Q9H0A0] xref: EMBL:AB051496 xref: EMBL:AF489535 xref: EMBL:AK001636 xref: EMBL:AK022241 xref: EMBL:AL136882 xref: EMBL:BC035558 xref: HGNC:HGNC:29830 xref: UniGene:Hs.577281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038667 ! NAT10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011561 name: KLRC1_human def: "NKG2-A/NKG2-B type II integral membrane protein gene" [UniProtKB:P26715] synonym: "NKG2A" EXACT [UniProtKB:P26715] xref: EMBL:AF023840 xref: EMBL:AF461812 xref: EMBL:BC012550 xref: EMBL:BC053840 xref: EMBL:U54783 xref: EMBL:U54784 xref: EMBL:U54785 xref: EMBL:U54786 xref: EMBL:X54867 xref: EMBL:X54868 xref: HGNC:HGNC:6374 xref: UniGene:Hs.512576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036600 ! NKG2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011562 name: KLRC2_human def: "NKG2-C type II integral membrane protein gene" [UniProtKB:P26717] synonym: "NKG2C" EXACT [UniProtKB:P26717] xref: EMBL:AC068775 xref: EMBL:AF260134 xref: EMBL:AJ001684 xref: EMBL:BC093644 xref: EMBL:BC112039 xref: EMBL:X54869 xref: EMBL:Y13055 xref: HGNC:HGNC:6375 xref: UniGene:Hs.591157 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036594 ! NKG2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011565 name: NKX6-1_human def: "Homeobox protein Nkx-6.1 gene" [UniProtKB:P78426] synonym: "NKX6A" EXACT [UniProtKB:P78426] xref: EMBL:U66797 xref: EMBL:U66798 xref: EMBL:U66799 xref: HGNC:HGNC:7839 xref: UniGene:Hs.546270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037991 ! NKX61_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011566 name: NKX6-2_human def: "Homeobox protein Nkx-6.2 gene" [UniProtKB:Q9C056] synonym: "GTX" EXACT [UniProtKB:Q9C056] synonym: "NKX6B" EXACT [UniProtKB:Q9C056] xref: EMBL:AF184215 xref: EMBL:AL392043 xref: EMBL:BC101635 xref: EMBL:BC104823 xref: EMBL:CH471211 xref: HGNC:HGNC:19321 xref: UniGene:Hs.134013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037988 ! NKX62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011567 name: NKX6-3_human def: "Homeobox protein Nkx-6.3 gene" [UniProtKB:A6NJ46] xref: EMBL:AC113133 xref: EMBL:AK057898 xref: EMBL:CH471080 xref: HGNC:HGNC:26328 xref: UniGene:Hs.647132 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037987 ! NKX63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011573 name: NSF_human def: "Vesicle-fusing ATPase gene" [UniProtKB:P46459] xref: EMBL:AF102846 xref: EMBL:AF135168 xref: EMBL:BC030613 xref: EMBL:U03985 xref: HGNC:HGNC:8016 xref: UniGene:Hs.431279 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038850 ! NSF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011575 name: OR6M1_human def: "Olfactory receptor 6M1 gene" [UniProtKB:Q8NGM8] xref: EMBL:AB065762 xref: EMBL:AF399606 xref: EMBL:BK004493 xref: HGNC:HGNC:14711 xref: UniGene:Hs.557924 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038592 ! OR6M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011597 name: PDX1_human def: "Pancreas/duodenum homeobox protein 1 gene" [UniProtKB:P52945] synonym: "IPF1" EXACT [UniProtKB:P52945] xref: EMBL:AF035259 xref: EMBL:AF035260 xref: EMBL:AF049893 xref: EMBL:S82168 xref: EMBL:S82178 xref: EMBL:U30329 xref: EMBL:U35632 xref: EMBL:X99894 xref: HGNC:HGNC:6107 xref: UniGene:Hs.32938 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036805 ! PDX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011598 name: PTGER3_human def: "Prostaglandin E2 receptor EP3 subtype gene" [UniProtKB:P43115] xref: EMBL:AL031429 xref: EMBL:AL158087 xref: EMBL:AY429108 xref: EMBL:BC024229 xref: EMBL:BC118578 xref: EMBL:CH471059 xref: EMBL:D38297 xref: EMBL:D38298 xref: EMBL:D38299 xref: EMBL:D38300 xref: EMBL:D38301 xref: EMBL:D86096 xref: EMBL:D86097 xref: EMBL:D86098 xref: EMBL:L26976 xref: EMBL:L27488 xref: EMBL:L27489 xref: EMBL:L27490 xref: EMBL:L32660 xref: EMBL:L32661 xref: EMBL:L32662 xref: EMBL:S69200 xref: EMBL:S69326 xref: EMBL:U13214 xref: EMBL:U13215 xref: EMBL:U13216 xref: EMBL:U13217 xref: EMBL:U13218 xref: EMBL:X83857 xref: EMBL:X83858 xref: EMBL:X83859 xref: EMBL:X83860 xref: EMBL:X83861 xref: EMBL:X83862 xref: EMBL:X83863 xref: HGNC:HGNC:9595 xref: UniGene:Hs.445000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037223 ! A8MSY3_HUMAN relationship: codes_for CCO:B0037226 ! O00325_HUMAN relationship: codes_for CCO:B0037229 ! PE2R3_HUMAN relationship: codes_for CCO:B0037236 ! Q147X8_HUMAN relationship: codes_for CCO:B0054224 ! B1AK19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011599 name: PEPD_human def: "Xaa-Pro dipeptidase gene" [UniProtKB:P12955] synonym: "PRD" EXACT [UniProtKB:P12955] xref: EMBL:BC004305 xref: EMBL:BC015027 xref: EMBL:BC028295 xref: EMBL:BT006692 xref: EMBL:J04605 xref: HGNC:HGNC:8840 xref: UniGene:Hs.36473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036047 ! PEPD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011600 name: VBP1_human def: "Prefoldin subunit 3 gene" [UniProtKB:P61758] synonym: "PFDN3" EXACT [UniProtKB:P61758] xref: EMBL:AL356738 xref: EMBL:BC046094 xref: EMBL:BT019604 xref: EMBL:U56833 xref: EMBL:U96759 xref: EMBL:Y17394 xref: HGNC:HGNC:12662 xref: UniGene:Hs.436803 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038197 ! PFD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011603 name: PHF12_human def: "PHD finger protein 12 gene" [UniProtKB:Q96QT6] synonym: "KIAA1523" EXACT [UniProtKB:Q96QT6] xref: EMBL:AB040956 xref: EMBL:AK024290 xref: EMBL:AK160370 xref: EMBL:AY030283 xref: EMBL:BC001657 xref: HGNC:HGNC:20816 xref: UniGene:Hs.444173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039070 ! PHF12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011609 name: PIM1_human def: "Proto-oncogene serine/threonine-protein kinase Pim-1 gene" [UniProtKB:P11309] xref: EMBL:AF386792 xref: EMBL:BC020224 xref: EMBL:DQ022562 xref: EMBL:M16750 xref: EMBL:M24779 xref: EMBL:M27903 xref: EMBL:M54915 xref: HGNC:HGNC:8986 xref: UniGene:Hs.81170 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022781 ! PIM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011611 name: PIWIL1_human def: "Piwi-like protein 1 gene" [UniProtKB:Q96J94] synonym: "HIWI" EXACT [UniProtKB:Q96J94] xref: EMBL:AF104260 xref: EMBL:AF264004 xref: EMBL:AF387507 xref: EMBL:AK093133 xref: EMBL:BC028581 xref: HGNC:HGNC:9007 xref: UniGene:Hs.405659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019369 ! PIWL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011613 name: PIWIL4_human def: "Piwi-like protein 4 gene" [UniProtKB:Q7Z3Z4] synonym: "HILI2" EXACT [UniProtKB:Q7Z3Z4] synonym: "PIWI" EXACT [UniProtKB:Q7Z3Z4] xref: EMBL:AB079366 xref: EMBL:AK093475 xref: EMBL:AK096837 xref: EMBL:BC031060 xref: EMBL:CR749642 xref: HGNC:HGNC:18444 xref: UniGene:Hs.660188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019368 ! PIWL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011614 name: PLSCR1_human def: "Phospholipid scramblase 1 gene" [UniProtKB:O15162] xref: EMBL:AB006746 xref: EMBL:AF098642 xref: EMBL:AF224492 xref: EMBL:BC021100 xref: EMBL:BC032718 xref: HGNC:HGNC:9092 xref: UniGene:Hs.130759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038636 ! PLS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011618 name: PMS2L1_human def: "Postmeiotic segregation increased 2-like protein 1 gene" [UniProtKB:A4D2B8] synonym: "PMS2L13" EXACT [UniProtKB:A4D2B8] synonym: "PMS2L6" EXACT [UniProtKB:A4D2B8] synonym: "PMS3" EXACT [UniProtKB:A4D2B8] synonym: "PMS8" EXACT [UniProtKB:A4D2B8] xref: EMBL:AB017004 xref: EMBL:BC067809 xref: EMBL:BC110395 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: EMBL:D38435 xref: EMBL:D38499 xref: HGNC:HGNC:9123 xref: UniGene:Hs.634244 xref: UniGene:Hs.654752 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025463 ! PM2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011619 name: PMS2L2_human def: "Postmeiotic segregation increased 2-like protein 2 gene" [UniProtKB:O95744] synonym: "PMS2L14" EXACT [UniProtKB:O95744] synonym: "PMS4" EXACT [UniProtKB:O95744] xref: EMBL:AB017005 xref: HGNC:HGNC:9127 xref: UniGene:Hs.292996 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025459 ! PM2L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011620 name: PMS2L8_human def: "Postmeiotic segregation increased 2-like protein 8 gene" [UniProtKB:Q13400] synonym: "PMSR2" EXACT [UniProtKB:Q13400] xref: EMBL:U38964 xref: HGNC:HGNC:9133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025464 ! PM2L8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011621 name: PMM1_human def: "Phosphomannomutase 1 gene" [UniProtKB:Q92871] synonym: "PMMH22" EXACT [UniProtKB:Q92871] xref: EMBL:AL023553 xref: EMBL:BC010855 xref: EMBL:BC016818 xref: EMBL:CR456544 xref: EMBL:D87810 xref: EMBL:U62526 xref: EMBL:U86070 xref: HGNC:HGNC:9114 xref: UniGene:Hs.75835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037580 ! PMM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011623 name: PMS2CL_human def: "Protein PMS2CL gene" [UniProtKB:Q68D20] xref: EMBL:AB116525 xref: EMBL:BC041364 xref: EMBL:CR749616 xref: HGNC:HGNC:30061 xref: UniGene:Hs.73105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025455 ! PMS2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011624 name: PMS4L_human def: "Postmeiotic segregation increased 4-like protein gene" [UniProtKB:A4D2C0] xref: EMBL:CH236956 xref: UniGene:Hs.634244 xref: UniGene:Hs.654752 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025457 ! PMS4L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011628 name: PREX1_human def: "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein gene" [UniProtKB:Q8TCU6] synonym: "KIAA1415" EXACT [UniProtKB:Q8TCU6] xref: EMBL:AB037836 xref: EMBL:AJ320261 xref: EMBL:AL035106 xref: EMBL:AL133342 xref: EMBL:AL136579 xref: EMBL:AL445192 xref: EMBL:AL832913 xref: EMBL:BC053616 xref: UniGene:Hs.153310 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037021 ! PREX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011629 name: PSMC6_human def: "26S protease regulatory subunit S10B gene" [UniProtKB:P62333] synonym: "SUG2" EXACT [UniProtKB:P62333] xref: EMBL:AF006305 xref: EMBL:BC005390 xref: EMBL:BT006843 xref: EMBL:CR456709 xref: EMBL:D78275 xref: HGNC:HGNC:9553 xref: UniGene:Hs.156171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030905 ! PRS10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011631 name: PSMB5_human def: "Proteasome subunit beta type-5 precursor gene" [UniProtKB:P28074] synonym: "LMPX" EXACT [UniProtKB:P28074] xref: EMBL:BC004146 xref: EMBL:BC057840 xref: EMBL:BC107720 xref: EMBL:BT006777 xref: EMBL:BX538001 xref: EMBL:D29011 xref: EMBL:S74378 xref: EMBL:X95586 xref: HGNC:HGNC:9542 xref: UniGene:Hs.422990 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030806 ! PSB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011632 name: PSMB8_human def: "Proteasome subunit beta type-8 precursor gene" [UniProtKB:P28062] synonym: "LMP7" EXACT [UniProtKB:P28062] synonym: "RING10" EXACT [UniProtKB:P28062] synonym: "Y2" EXACT [UniProtKB:P28062] xref: EMBL:AL669918 xref: EMBL:AL671681 xref: EMBL:AL935043 xref: EMBL:BC001114 xref: EMBL:BX088556 xref: EMBL:BX682530 xref: EMBL:BX927138 xref: EMBL:CR762476 xref: EMBL:CT009502 xref: EMBL:L11045 xref: EMBL:U17496 xref: EMBL:U17497 xref: EMBL:U32862 xref: EMBL:U32863 xref: EMBL:X62598 xref: EMBL:X66401 xref: EMBL:X87344 xref: EMBL:Z14982 xref: HGNC:HGNC:9545 xref: UniGene:Hs.180062 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030804 ! PSB8_HUMAN relationship: codes_for CCO:B0030810 ! Q5JNW7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011633 name: PSMD12_human def: "26S proteasome non-ATPase regulatory subunit 12 gene" [UniProtKB:O00232] xref: EMBL:AB003103 xref: EMBL:AK222679 xref: EMBL:BC019062 xref: EMBL:BC065826 xref: HGNC:HGNC:9557 xref: UniGene:Hs.646575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038144 ! PSD12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011635 name: PTBP1_human def: "Polypyrimidine tract-binding protein 1 gene" [UniProtKB:P26599] synonym: "PTB" EXACT [UniProtKB:P26599] xref: EMBL:AC006273 xref: EMBL:BC004383 xref: EMBL:X60648 xref: EMBL:X62006 xref: EMBL:X65371 xref: EMBL:X65372 xref: EMBL:X66975 xref: HGNC:HGNC:9583 xref: UniGene:Hs.172550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037269 ! PTBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011641 name: PPP2R4_human def: "Serine/threonine-protein phosphatase 2A regulatory subunit B' gene" [UniProtKB:Q15257] synonym: "PTPA" EXACT [UniProtKB:Q15257] xref: EMBL:AK222788 xref: EMBL:AL158151 xref: EMBL:BC002545 xref: EMBL:BC011605 xref: EMBL:BT020119 xref: EMBL:X73478 xref: EMBL:X86428 xref: EMBL:X86429 xref: EMBL:X86430 xref: EMBL:X86431 xref: EMBL:X86432 xref: EMBL:X86434 xref: EMBL:X86435 xref: EMBL:X86436 xref: EMBL:X86437 xref: EMBL:X86438 xref: EMBL:X86439 xref: HGNC:HGNC:9308 xref: UniGene:Hs.400740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025635 ! PTPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011642 name: PXK_human def: "PX domain-containing protein kinase-like protein gene" [UniProtKB:Q7Z7A4] xref: EMBL:AB209688 xref: EMBL:AF399753 xref: EMBL:AK000342 xref: EMBL:AK131385 xref: EMBL:AY274811 xref: EMBL:AY437879 xref: EMBL:AY847220 xref: EMBL:AY847221 xref: EMBL:AY847222 xref: EMBL:BC008943 xref: EMBL:BC014479 xref: EMBL:DQ124707 xref: EMBL:DQ124708 xref: HGNC:HGNC:23326 xref: UniGene:Hs.190544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037398 ! PXK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011647 name: RAB11A_human def: "Ras-related protein Rab-11A gene" [UniProtKB:P62491] synonym: "RAB11" EXACT [UniProtKB:P62491] xref: EMBL:AF000231 xref: EMBL:AF498946 xref: EMBL:BC013348 xref: EMBL:BT020151 xref: EMBL:BT020154 xref: EMBL:CR407669 xref: EMBL:CR536493 xref: EMBL:X53143 xref: EMBL:X56740 xref: HGNC:HGNC:9760 xref: UniGene:Hs.321541 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038438 ! RB11A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011648 name: RAB11B_human def: "Ras-related protein Rab-11B gene" [UniProtKB:Q15907] synonym: "YPT3" EXACT [UniProtKB:Q15907] xref: EMBL:AF498947 xref: EMBL:BC110081 xref: EMBL:BT019536 xref: EMBL:X79780 xref: HGNC:HGNC:9761 xref: UniGene:Hs.626404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038434 ! RB11B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011649 name: RLN1_human def: "Prorelaxin H1 precursor gene" [UniProtKB:P04808] xref: EMBL:AF104934 xref: EMBL:AL135786 xref: EMBL:BC005956 xref: EMBL:S83200 xref: EMBL:V00577 xref: EMBL:V00578 xref: EMBL:X00949 xref: HGNC:HGNC:10026 xref: UniGene:Hs.368996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038671 ! REL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011651 name: RFC2_human def: "Replication factor C subunit 2 gene" [UniProtKB:P35250] xref: EMBL:AC005081 xref: EMBL:AF045555 xref: EMBL:AF483622 xref: EMBL:BC002813 xref: EMBL:M87338 xref: HGNC:HGNC:9970 xref: UniGene:Hs.647062 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036627 ! RFC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011652 name: RFC4_human def: "Replication factor C subunit 4 gene" [UniProtKB:P35249] xref: EMBL:AF538718 xref: EMBL:BC017452 xref: EMBL:BC024022 xref: EMBL:BT006987 xref: EMBL:CR536561 xref: EMBL:M87339 xref: HGNC:HGNC:9972 xref: UniGene:Hs.518475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017957 ! RFC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011653 name: RALGPS2_human def: "Ras-specific guanine nucleotide-releasing factor RalGPS2 gene" [UniProtKB:Q86X27] xref: EMBL:AK001106 xref: EMBL:AL162255 xref: EMBL:AL355520 xref: EMBL:BC047391 xref: EMBL:CH471067 xref: HGNC:HGNC:30279 xref: UniGene:Hs.644008 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037994 ! RGPS2_HUMAN relationship: codes_for CCO:B0042581 ! B1AMV0_HUMAN relationship: codes_for CCO:B0042582 ! B1AMV1_HUMAN relationship: codes_for CCO:B0042583 ! B1AMV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011654 name: ARHGAP5_human def: "Rho GTPase-activating protein 5 gene" [UniProtKB:Q13017] synonym: "RHOGAP5" EXACT [UniProtKB:Q13017] xref: EMBL:AB209751 xref: EMBL:AK292966 xref: EMBL:BC032723 xref: EMBL:BC050059 xref: EMBL:BC075799 xref: EMBL:BC129928 xref: EMBL:BC129929 xref: EMBL:U17032 xref: HGNC:HGNC:675 xref: UniGene:Hs.592313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019383 ! RHG05_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011655 name: RHOA_human def: "Transforming protein RhoA precursor gene" [UniProtKB:P61586] synonym: "ARH12" EXACT [UniProtKB:P61586] synonym: "ARHA" EXACT [UniProtKB:P61586] synonym: "RHO12" EXACT [UniProtKB:P61586] xref: EMBL:AF498970 xref: EMBL:BC001360 xref: EMBL:BC005976 xref: EMBL:BT019870 xref: EMBL:BX647063 xref: EMBL:L09159 xref: EMBL:L25080 xref: EMBL:M83094 xref: EMBL:X05026 xref: HGNC:HGNC:667 xref: UniGene:Hs.247077 xref: UniGene:Hs.657976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020591 ! RHOA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011656 name: RHOC_human def: "Rho-related GTP-binding protein RhoC precursor gene" [UniProtKB:P08134] synonym: "ARH9" EXACT [UniProtKB:P08134] synonym: "ARHC" EXACT [UniProtKB:P08134] xref: EMBL:AF498972 xref: EMBL:AL603832 xref: EMBL:BC007245 xref: EMBL:BC009177 xref: EMBL:BC052808 xref: EMBL:BT019448 xref: EMBL:CR450360 xref: EMBL:L25081 xref: EMBL:X06821 xref: HGNC:HGNC:669 xref: UniGene:Hs.502659 xref: UniGene:Hs.658289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020594 ! RHOC_HUMAN relationship: codes_for CCO:B0020597 ! Q5JR08_HUMAN relationship: codes_for CCO:B0056460 ! Q5JR05_HUMAN relationship: codes_for CCO:B0056461 ! Q5JR06_HUMAN relationship: codes_for CCO:B0056462 ! Q5JR07_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011660 name: RMND5B_human def: "Protein RMD5 homolog B gene" [UniProtKB:Q96G75] synonym: "UNQ2508/PRO5996" EXACT [UniProtKB:Q96G75] xref: EMBL:AK025971 xref: EMBL:AL713670 xref: EMBL:AY359092 xref: EMBL:BC009911 xref: HGNC:HGNC:26181 xref: UniGene:Hs.519804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037027 ! RMD5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011662 name: POLR2A_human def: "DNA-directed RNA polymerase II subunit RPB1 gene" [UniProtKB:P24928] xref: EMBL:X63564 xref: EMBL:X74870 xref: EMBL:X74871 xref: EMBL:X74872 xref: EMBL:X74873 xref: EMBL:X74874 xref: HGNC:HGNC:9187 xref: UniGene:Hs.270017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021690 ! RPB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011663 name: RAPGEF1_human def: "Rap guanine nucleotide exchange factor 1 gene" [UniProtKB:Q13905] synonym: "GRF2" EXACT [UniProtKB:Q13905] xref: EMBL:AL160271 xref: EMBL:AL160276 xref: EMBL:BC041710 xref: EMBL:D21239 xref: EMBL:DQ925677 xref: EMBL:DQ925678 xref: EMBL:DQ925682 xref: HGNC:HGNC:4568 xref: UniGene:Hs.127897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038385 ! RPGF1_HUMAN relationship: codes_for CCO:B0038386 ! Q5JUE5_HUMAN relationship: codes_for CCO:B0038390 ! Q5JUE9_HUMAN relationship: codes_for CCO:B0038391 ! Q8IV73_HUMAN relationship: codes_for CCO:B0053777 ! A5XEI4_HUMAN relationship: codes_for CCO:B0053778 ! A5XEI5_HUMAN relationship: codes_for CCO:B0053779 ! A5XEI9_HUMAN relationship: codes_for CCO:B0056487 ! Q5JUE7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011664 name: RPIA_human def: "Ribose-5-phosphate isomerase gene" [UniProtKB:P49247] synonym: "RPI" EXACT [UniProtKB:P49247] xref: EMBL:AY050633 xref: EMBL:BC015529 xref: EMBL:L35035 xref: HGNC:HGNC:10297 xref: UniGene:Hs.469264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024182 ! RPIA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011665 name: RRBP1_human def: "Ribosome-binding protein 1 gene" [UniProtKB:Q9P2E9] synonym: "KIAA1398" EXACT [UniProtKB:Q9P2E9] xref: EMBL:AB037819 xref: EMBL:AF006751 xref: EMBL:AF007575 xref: EMBL:AL132765 xref: EMBL:AL833822 xref: EMBL:BC000099 xref: HGNC:HGNC:10448 xref: UniGene:Hs.472213 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037300 ! RRBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011667 name: RXFP1_human def: "Relaxin receptor 1 gene" [UniProtKB:Q9HBX9] synonym: "LGR7" EXACT [UniProtKB:Q9HBX9] xref: EMBL:AF190500 xref: EMBL:AY899848 xref: EMBL:AY899849 xref: EMBL:AY899850 xref: EMBL:BC112142 xref: EMBL:BC113617 xref: EMBL:CH471056 xref: HGNC:HGNC:19718 xref: UniGene:Hs.591686 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037085 ! RXFP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011668 name: RXFP2_human def: "Relaxin receptor 2 gene" [UniProtKB:Q8WXD0] synonym: "GPR106" EXACT [UniProtKB:Q8WXD0] synonym: "GREAT" EXACT [UniProtKB:Q8WXD0] synonym: "LGR8" EXACT [UniProtKB:Q8WXD0] xref: EMBL:AF403384 xref: EMBL:AF453828 xref: HGNC:HGNC:17318 xref: UniGene:Hs.680763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037083 ! RXFP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011676 name: SENP2_human def: "Sentrin-specific protease 2 gene" [UniProtKB:Q9HC62] synonym: "KIAA1331" EXACT [UniProtKB:Q9HC62] xref: EMBL:AB037752 xref: EMBL:AF151697 xref: EMBL:AK027599 xref: EMBL:AL834380 xref: EMBL:BC040609 xref: HGNC:HGNC:23116 xref: UniGene:Hs.401388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036139 ! SENP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011682 name: SMC6_human def: "Structural maintenance of chromosomes protein 6 gene" [UniProtKB:Q96SB8] synonym: "SMC6L1" EXACT [UniProtKB:Q96SB8] xref: EMBL:AC097377 xref: EMBL:AJ310551 xref: EMBL:AK025769 xref: EMBL:AL136544 xref: EMBL:AL832979 xref: EMBL:BC032675 xref: EMBL:BC039828 xref: HGNC:HGNC:20466 xref: UniGene:Hs.526728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022073 ! SMC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011683 name: SOX17_human def: "Transcription factor SOX-17 gene" [UniProtKB:Q9H6I2] xref: EMBL:AB073988 xref: EMBL:AK025905 xref: HGNC:HGNC:18122 xref: UniGene:Hs.98367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037399 ! SOX17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011684 name: SPHK2_human def: "Sphingosine kinase 2 gene" [UniProtKB:Q9NRA0] xref: EMBL:AF245447 xref: EMBL:AK000599 xref: EMBL:AL136701 xref: EMBL:BC006161 xref: EMBL:BC010671 xref: EMBL:EF107108 xref: HGNC:HGNC:18859 xref: UniGene:Hs.528006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036431 ! SPHK2_HUMAN relationship: codes_for CCO:B0036434 ! A0T4C8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011685 name: SPATA13_human def: "Spermatogenesis-associated protein 13 gene" [UniProtKB:Q96N96] xref: EMBL:AK055770 xref: EMBL:AK074117 xref: EMBL:AK097217 xref: EMBL:AK123031 xref: EMBL:AK160371 xref: EMBL:AL359736 xref: EMBL:BC109290 xref: EMBL:BC109291 xref: HGNC:HGNC:23222 xref: UniGene:Hs.657121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037019 ! SPT13_HUMAN relationship: codes_for CCO:B0037023 ! Q5VX68_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011686 name: STK17A_human def: "Serine/threonine-protein kinase 17A gene" [UniProtKB:Q9UEE5] synonym: "DRAK1" EXACT [UniProtKB:Q9UEE5] xref: EMBL:AB011420 xref: EMBL:BC023508 xref: EMBL:BC047696 xref: HGNC:HGNC:11395 xref: UniGene:Hs.699353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036514 ! ST17A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011687 name: STK17B_human def: "Serine/threonine-protein kinase 17B gene" [UniProtKB:O94768] synonym: "DRAK2" EXACT [UniProtKB:O94768] xref: EMBL:AB011421 xref: EMBL:BC016040 xref: HGNC:HGNC:11396 xref: UniGene:Hs.88297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036523 ! ST17B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011697 name: GARS_human def: "Glycyl-tRNA synthetase gene" [UniProtKB:P41250] xref: EMBL:AC004976 xref: EMBL:BC007722 xref: EMBL:BC007755 xref: EMBL:D30658 xref: EMBL:U09510 xref: EMBL:U09587 xref: HGNC:HGNC:4162 xref: UniGene:Hs.404321 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038779 ! SYG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011701 name: SNCA_human def: "Alpha-synuclein gene" [UniProtKB:P37840] synonym: "NACP" EXACT [UniProtKB:P37840] synonym: "PARK1" EXACT [UniProtKB:P37840] xref: EMBL:AF163864 xref: EMBL:AY049786 xref: EMBL:BC013293 xref: EMBL:BC108275 xref: EMBL:CR457058 xref: EMBL:D31839 xref: EMBL:DQ088379 xref: EMBL:L08850 xref: EMBL:L36674 xref: EMBL:L36675 xref: EMBL:U46897 xref: EMBL:U46898 xref: EMBL:U46899 xref: EMBL:U46901 xref: HGNC:HGNC:11138 xref: UniGene:Hs.271771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018239 ! SYUA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011704 name: TAF13_human def: "Transcription initiation factor TFIID subunit 13 gene" [UniProtKB:Q15543] synonym: "TAF2K" EXACT [UniProtKB:Q15543] synonym: "TAFII18" EXACT [UniProtKB:Q15543] xref: EMBL:BC121180 xref: EMBL:BX679664 xref: EMBL:X84003 xref: HGNC:HGNC:11546 xref: UniGene:Hs.632426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038317 ! TAF13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011705 name: TALDO1_human def: "Transaldolase gene" [UniProtKB:P37837] synonym: "TAL" EXACT [UniProtKB:P37837] synonym: "TALDO" EXACT [UniProtKB:P37837] synonym: "TALDOR" EXACT [UniProtKB:P37837] xref: EMBL:AF010398 xref: EMBL:AF010399 xref: EMBL:AF010400 xref: EMBL:AF058913 xref: EMBL:BC010103 xref: EMBL:BC018847 xref: EMBL:L19437 xref: HGNC:HGNC:11559 xref: UniGene:Hs.438678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020161 ! TALDO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011706 name: TPT1_human def: "Translationally-controlled tumor protein gene" [UniProtKB:P13693] xref: EMBL:AJ400717 xref: EMBL:AL138963 xref: EMBL:AY117678 xref: EMBL:AY334563 xref: EMBL:BC003352 xref: EMBL:BC012431 xref: EMBL:BC052333 xref: EMBL:CR457036 xref: EMBL:X16064 xref: HGNC:HGNC:12022 xref: UniGene:Hs.374596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036188 ! TCTP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011707 name: TGFBR1_human def: "TGF-beta receptor type-1 precursor gene" [UniProtKB:P36897] xref: EMBL:AF035662 xref: EMBL:AF035663 xref: EMBL:AF035664 xref: EMBL:AF035665 xref: EMBL:AF035666 xref: EMBL:AF035667 xref: EMBL:AF035668 xref: EMBL:AF035669 xref: EMBL:AF035670 xref: EMBL:AF054590 xref: EMBL:AF054591 xref: EMBL:AF054592 xref: EMBL:AF054593 xref: EMBL:AF054594 xref: EMBL:AF054595 xref: EMBL:AF054596 xref: EMBL:AF054597 xref: EMBL:AF054598 xref: EMBL:AY497473 xref: EMBL:BC071181 xref: EMBL:L11695 xref: HGNC:HGNC:11772 xref: UniGene:Hs.494622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020367 ! Q6IR47_HUMAN relationship: codes_for CCO:B0020370 ! TGFR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011710 name: TRIM24_human def: "Transcription intermediary factor 1-alpha gene" [UniProtKB:O15164] synonym: "RNF82" EXACT [UniProtKB:O15164] synonym: "TIF1" EXACT [UniProtKB:O15164] synonym: "TIF1A" EXACT [UniProtKB:O15164] xref: EMBL:AF009353 xref: EMBL:AF119042 xref: EMBL:BC028689 xref: HGNC:HGNC:11812 xref: UniGene:Hs.490287 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037051 ! TIF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011711 name: TIGD3_human def: "Tigger transposable element-derived protein 3 gene" [UniProtKB:Q6B0B8] xref: EMBL:BC074862 xref: HGNC:HGNC:18334 xref: UniGene:Hs.632121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039136 ! TIGD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011713 name: TMED2_human def: "Transmembrane emp24 domain-containing protein 2 precursor gene" [UniProtKB:Q15363] synonym: "RNP24" EXACT [UniProtKB:Q15363] xref: EMBL:BC025957 xref: EMBL:X92098 xref: HGNC:HGNC:16996 xref: UniGene:Hs.592682 xref: UniGene:Hs.75914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038128 ! TMED2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011718 name: TNIP2_human def: "TNFAIP3-interacting protein 2 gene" [UniProtKB:Q8NFZ5] synonym: "ABIN2" EXACT [UniProtKB:Q8NFZ5] synonym: "FLIP1" EXACT [UniProtKB:Q8NFZ5] xref: EMBL:AF372839 xref: EMBL:AJ304866 xref: EMBL:AK026176 xref: EMBL:BC002740 xref: EMBL:CH471131 xref: HGNC:HGNC:19118 xref: UniGene:Hs.368551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037117 ! TNIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011719 name: TRIM33_human def: "E3 ubiquitin-protein ligase TRIM33 gene" [UniProtKB:Q9UPN9] synonym: "KIAA1113" EXACT [UniProtKB:Q9UPN9] synonym: "RFG7" EXACT [UniProtKB:Q9UPN9] synonym: "TIF1G" EXACT [UniProtKB:Q9UPN9] xref: EMBL:AB029036 xref: EMBL:AF119043 xref: EMBL:AF220136 xref: EMBL:AF220137 xref: EMBL:AJ132948 xref: EMBL:AL035410 xref: EMBL:AL390241 xref: HGNC:HGNC:16290 xref: UniGene:Hs.26837 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037050 ! TRI33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011720 name: TRIM66_human def: "Tripartite motif-containing protein 66 gene" [UniProtKB:O15016] synonym: "KIAA0298" EXACT [UniProtKB:O15016] xref: EMBL:AB002296 xref: EMBL:AJ400879 xref: HGNC:HGNC:29005 xref: UniGene:Hs.130836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037049 ! TRI66_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011721 name: TRPV1_human def: "Transient receptor potential cation channel subfamily V member 1 gene" [UniProtKB:Q8NER1] synonym: "VR1" EXACT [UniProtKB:Q8NER1] xref: EMBL:AF196175 xref: EMBL:AF196176 xref: EMBL:AJ272063 xref: EMBL:AJ277028 xref: EMBL:AL136801 xref: EMBL:AY131289 xref: HGNC:HGNC:12716 xref: UniGene:Hs.579217 xref: UniGene:Hs.655380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038932 ! TRPV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011724 name: TRPV4_human def: "Transient receptor potential cation channel subfamily V member 4 gene" [UniProtKB:Q9HBA0] synonym: "VRL2" EXACT [UniProtKB:Q9HBA0] synonym: "VROAC" EXACT [UniProtKB:Q9HBA0] xref: EMBL:AB032427 xref: EMBL:AB073669 xref: EMBL:AB100308 xref: EMBL:AF258465 xref: EMBL:AF263523 xref: EMBL:AF279673 xref: EMBL:AJ296305 xref: EMBL:BC117426 xref: EMBL:DQ059644 xref: EMBL:DQ059645 xref: EMBL:DQ059646 xref: HGNC:HGNC:18083 xref: UniGene:Hs.506713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038926 ! TRPV4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011743 name: XPO5_human def: "Exportin-5 gene" [UniProtKB:Q9HAV4] synonym: "KIAA1291" EXACT [UniProtKB:Q9HAV4] synonym: "RANBP21" EXACT [UniProtKB:Q9HAV4] xref: EMBL:AB033117 xref: EMBL:AF271159 xref: EMBL:AF298880 xref: EMBL:AK001195 xref: EMBL:AK022718 xref: EMBL:AL137467 xref: EMBL:AL355802 xref: EMBL:BC000129 xref: EMBL:BC008347 xref: EMBL:BC009969 xref: EMBL:BC062635 xref: HGNC:HGNC:17675 xref: UniGene:Hs.203206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037436 ! XPO5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011744 name: ZBTB40_human def: "Zinc finger and BTB domain-containing protein 40 gene" [UniProtKB:Q9NUA8] synonym: "KIAA0478" EXACT [UniProtKB:Q9NUA8] xref: EMBL:AB007947 xref: EMBL:AK095273 xref: EMBL:AL035703 xref: HGNC:HGNC:29045 xref: UniGene:Hs.418966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037805 ! ZBT40_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011745 name: ZFP64_human def: "Zinc finger protein 64 homolog, isoforms 1 and 2 gene" [UniProtKB:Q9NPA5] synonym: "ZNF338" EXACT [UniProtKB:Q9NPA5] xref: EMBL:AK001596 xref: EMBL:AK001744 xref: EMBL:AK022690 xref: EMBL:AL109984 xref: EMBL:AL121771 xref: EMBL:BC012759 xref: EMBL:BC021087 xref: EMBL:BC041622 xref: HGNC:HGNC:15940 xref: UniGene:Hs.473082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037138 ! ZF64B_HUMAN relationship: codes_for CCO:B0037139 ! ZF64A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011746 name: ZIK1_human def: "Zinc finger protein interacting with ribonucleoprotein K gene" [UniProtKB:Q3SY52] synonym: "ZNF762" EXACT [UniProtKB:Q3SY52] xref: EMBL:AC003682 xref: EMBL:BC103957 xref: EMBL:BC103958 xref: EMBL:BC103959 xref: HGNC:HGNC:33104 xref: UniGene:Hs.454830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039097 ! A6NLI9_HUMAN relationship: codes_for CCO:B0039109 ! ZIK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011747 name: ZNF100_human def: "Zinc finger protein 100 gene" [UniProtKB:Q8IYN0] xref: EMBL:BC031248 xref: EMBL:BC035579 xref: HGNC:HGNC:12880 xref: UniGene:Hs.365142 xref: UniGene:Hs.670568 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037089 ! ZN100_HUMAN relationship: codes_for CCO:B0048591 ! Q4G131_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011748 name: ZNF134_human def: "Zinc finger protein 134 gene" [UniProtKB:P52741] xref: EMBL:AC003682 xref: EMBL:AK291763 xref: EMBL:BC112294 xref: EMBL:BC113410 xref: EMBL:CH471135 xref: EMBL:U09412 xref: HGNC:HGNC:12918 xref: UniGene:Hs.469694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039104 ! ZN134_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011749 name: ZNF154_human def: "Zinc finger protein 154 gene" [UniProtKB:Q13106] synonym: "KIAA2003" EXACT [UniProtKB:Q13106] xref: EMBL:AB095924 xref: EMBL:AK092261 xref: EMBL:U20648 xref: HGNC:HGNC:12939 xref: UniGene:Hs.646378 xref: UniGene:Hs.649031 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039114 ! ZN154_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011750 name: ZNF175_human def: "Zinc finger protein 175 gene" [UniProtKB:Q9Y473] xref: EMBL:AC018755 xref: EMBL:BC052997 xref: EMBL:D50419 xref: HGNC:HGNC:12964 xref: UniGene:Hs.119014 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037975 ! ZN175_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011751 name: ZNF211_human def: "Zinc finger protein 211 gene" [UniProtKB:Q13398] xref: EMBL:AB209273 xref: EMBL:AB209847 xref: EMBL:AK294869 xref: EMBL:AK296942 xref: EMBL:AK297047 xref: EMBL:AK304666 xref: EMBL:BC034351 xref: EMBL:BC089440 xref: EMBL:BC110856 xref: EMBL:U38904 xref: HGNC:HGNC:13003 xref: UniGene:Hs.590977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039108 ! ZN211_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011752 name: ZNF273_human def: "Zinc finger protein 273 gene" [UniProtKB:Q14593] xref: EMBL:BC063818 xref: EMBL:X78932 xref: HGNC:HGNC:13067 xref: UniGene:Hs.520889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037105 ! ZN273_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011753 name: ZNF295_human def: "Zinc finger protein 295 gene" [UniProtKB:Q9ULJ3] synonym: "KIAA1227" EXACT [UniProtKB:Q9ULJ3] synonym: "ZBTB21" EXACT [UniProtKB:Q9ULJ3] xref: EMBL:AB033053 xref: EMBL:AP001745 xref: EMBL:BC063290 xref: HGNC:HGNC:13083 xref: UniGene:Hs.434947 xref: UniGene:Hs.618406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037120 ! ZN295_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011754 name: ZNF419_human def: "Zinc finger protein 419 gene" [UniProtKB:Q96HQ0] synonym: "ZNF419A" EXACT [UniProtKB:Q96HQ0] xref: EMBL:AC003005 xref: EMBL:AK026886 xref: EMBL:BC008297 xref: EMBL:BC024259 xref: HGNC:HGNC:20648 xref: UniGene:Hs.579576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039102 ! ZN419_HUMAN relationship: codes_for CCO:B0039107 ! A6NNZ3_HUMAN relationship: codes_for CCO:B0039112 ! A6NL30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011755 name: ZNF429_human def: "Zinc finger protein 429 gene" [UniProtKB:Q86V71] xref: EMBL:AC010615 xref: EMBL:AY269786 xref: HGNC:HGNC:20817 xref: UniGene:Hs.572567 xref: UniGene:Hs.656558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037098 ! ZN429_HUMAN relationship: codes_for CCO:B0053900 ! A6NLV7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011756 name: ZNF430_human def: "Zinc finger protein 430 gene" [UniProtKB:Q9H8G1] xref: EMBL:AK023721 xref: EMBL:AY269787 xref: HGNC:HGNC:20808 xref: UniGene:Hs.466289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037112 ! ZN430_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011757 name: ZNF431_human def: "Zinc finger protein 431 gene" [UniProtKB:Q8TF32] synonym: "KIAA1969" EXACT [UniProtKB:Q8TF32] xref: EMBL:AB075849 xref: EMBL:BC040506 xref: HGNC:HGNC:20809 xref: UniGene:Hs.696753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037101 ! ZN431_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011758 name: ZNF479_human def: "Zinc finger protein 479 gene" [UniProtKB:Q96JC4] xref: EMBL:AF277624 xref: HGNC:HGNC:23258 xref: UniGene:Hs.616660 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037090 ! ZN479_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011759 name: ZNF548_human def: "Zinc finger protein 548 gene" [UniProtKB:Q8NEK5] xref: EMBL:AK057494 xref: EMBL:BC030788 xref: HGNC:HGNC:26561 xref: UniGene:Hs.657353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039101 ! ZN548_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011761 name: ZNF626_human def: "Zinc finger protein 626 gene" [UniProtKB:Q68DY1] xref: EMBL:AC010636 xref: EMBL:AK096221 xref: EMBL:AK131567 xref: EMBL:BC007116 xref: EMBL:BC107803 xref: EMBL:CH471106 xref: EMBL:CR749233 xref: HGNC:HGNC:30461 xref: UniGene:Hs.657001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032364 ! Q96QM1_HUMAN relationship: codes_for CCO:B0037096 ! ZN626_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011762 name: ZNF680_human def: "Zinc finger protein 680 gene" [UniProtKB:Q8NEM1] xref: EMBL:AK074911 xref: EMBL:AK131240 xref: EMBL:BC030700 xref: EMBL:CH471204 xref: HGNC:HGNC:26897 xref: UniGene:Hs.520886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032362 ! Q6ZNF3_HUMAN relationship: codes_for CCO:B0037093 ! ZN680_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011763 name: ZNF682_human def: "Zinc finger protein 682 gene" [UniProtKB:O95780] xref: EMBL:AC006539 xref: EMBL:AK027845 xref: EMBL:CH471106 xref: HGNC:HGNC:28857 xref: UniGene:Hs.306298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037092 ! ZN682_HUMAN relationship: codes_for CCO:B0037109 ! O95779_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011764 name: ZNF772_human def: "Zinc finger protein 772 gene" [UniProtKB:Q68DY9] xref: EMBL:AC004076 xref: EMBL:BX647068 xref: EMBL:CR749225 xref: HGNC:HGNC:33106 xref: UniGene:Hs.388810 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039099 ! A6NJK9_HUMAN relationship: codes_for CCO:B0039103 ! A6NKR6_HUMAN relationship: codes_for CCO:B0039105 ! ZN772_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011765 name: ZNF773_human def: "Zinc finger protein 773 gene" [UniProtKB:Q6PK81] synonym: "ZNF419B" EXACT [UniProtKB:Q6PK81] xref: EMBL:AK057209 xref: EMBL:BC005167 xref: HGNC:HGNC:30487 xref: UniGene:Hs.579576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039095 ! ZN773_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011766 name: ZNF776_human def: "Zinc finger protein 776 gene" [UniProtKB:Q68DI1] xref: EMBL:AK095607 xref: EMBL:AK127764 xref: EMBL:CR749390 xref: HGNC:HGNC:26765 xref: UniGene:Hs.109540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039094 ! ZN776_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011767 name: ZNF19_human def: "Zinc finger protein 19 gene" [UniProtKB:P17023] synonym: "KOX12" EXACT [UniProtKB:P17023] xref: EMBL:BC047091 xref: EMBL:M77171 xref: EMBL:X52343 xref: HGNC:HGNC:12981 xref: UniGene:Hs.656643 xref: UniGene:Hs.660076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038627 ! ZNF19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011768 name: ZNF81_human def: "Zinc finger protein 81 gene" [UniProtKB:P51508] xref: EMBL:AL022578 xref: EMBL:AL591394 xref: EMBL:AY487248 xref: EMBL:X68011 xref: EMBL:Z98304 xref: HGNC:HGNC:13156 xref: UniGene:Hs.114246 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037974 ! ZNF81_HUMAN relationship: codes_for CCO:B0054221 ! B1AJV1_HUMAN relationship: codes_for CCO:B0054222 ! B1AJV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011769 name: ZNF92_human def: "Zinc finger protein 92 gene" [UniProtKB:Q03936] xref: EMBL:AC092685 xref: EMBL:AK091618 xref: EMBL:BC036439 xref: EMBL:BC040594 xref: EMBL:M61872 xref: HGNC:HGNC:13168 xref: UniGene:Hs.9521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037110 ! ZNF92_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011773 name: HLA-DQB1_human def: "HLA class II histocompatibility antigen, DQB1*0602 beta chain precursor gene" [UniProtKB:P03992] xref: EMBL:L34105 xref: EMBL:M17207 xref: EMBL:M20432 xref: EMBL:M25327 xref: EMBL:M27656 xref: EMBL:M27657 xref: EMBL:M65048 xref: HGNC:HGNC:4944 xref: UniGene:Hs.409934 xref: UniGene:Hs.534322 xref: UniGene:Hs.697047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063249 ! HB25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011782 name: ZBTB4_human def: "Zinc finger and BTB domain-containing protein 4 gene" [UniProtKB:Q9P1Z0] synonym: "KIAA1538" EXACT [UniProtKB:Q9P1Z0] xref: EMBL:AB040971 xref: EMBL:AY302699 xref: EMBL:BC033259 xref: EMBL:BC043352 xref: HGNC:HGNC:23847 xref: UniGene:Hs.700622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059046 ! ZBTB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011795 name: LOC389527_human def: "Similar to PMS4 homolog mismatch repair protein-human gene" [UniProtKB:A4D2C1] synonym: "tcag7.1059" EXACT [UniProtKB:A4D2C1] xref: EMBL:CH236956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025454 ! A4D2C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011799 name: ZNF253_human def: "Zinc finger protein 253 gene" [UniProtKB:O75346] synonym: "BMZF1" EXACT [UniProtKB:O75346] synonym: "ZNF411" EXACT [UniProtKB:O75346] xref: EMBL:AF038951 xref: EMBL:BC125063 xref: HGNC:HGNC:13497 xref: UniGene:Hs.659321 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037103 ! A4FVA7_HUMAN relationship: codes_for CCO:B0054620 ! ZN253_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011801 name: ZNF551_human def: "Zinc finger protein 551 gene" [UniProtKB:Q7Z340] synonym: "KOX23" EXACT [UniProtKB:Q7Z340] xref: EMBL:AC004017 xref: EMBL:AK091273 xref: EMBL:BC005868 xref: EMBL:BC041615 xref: EMBL:BX538151 xref: EMBL:X52354 xref: HGNC:HGNC:25108 xref: UniGene:Hs.109540 xref: UniGene:Hs.656485 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039117 ! A6NGN8_HUMAN relationship: codes_for CCO:B0057144 ! ZN551_HUMAN relationship: codes_for CCO:B0057351 ! Q8IVY6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011806 name: OR6W1P_human def: "Putative uncharacterized protein OR6W1P gene" [UniProtKB:A6NJJ1] xref: EMBL:AC099652 xref: HGNC:HGNC:15091 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038594 ! A6NJJ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011807 name: VLDLR_human def: "Very low-density lipoprotein receptor precursor gene" [UniProtKB:P98155] xref: EMBL:AL450467 xref: EMBL:D16493 xref: EMBL:D16494 xref: EMBL:D16532 xref: EMBL:DQ067198 xref: EMBL:L20470 xref: EMBL:L22431 xref: EMBL:S73849 xref: HGNC:HGNC:12698 xref: UniGene:Hs.370422 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055669 ! VLDLR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011813 name: PPP1R13L_human def: "RelA-associated inhibitor gene" [UniProtKB:Q8WUF5] synonym: "IASPP" EXACT [UniProtKB:Q8WUF5] synonym: "NKIP1" EXACT [UniProtKB:Q8WUF5] synonym: "PPP1R13BL" EXACT [UniProtKB:Q8WUF5] synonym: "RAI" EXACT [UniProtKB:Q8WUF5] xref: EMBL:AF078036 xref: EMBL:AF078037 xref: EMBL:AJ888472 xref: EMBL:AY869712 xref: EMBL:BC001475 xref: EMBL:BC020589 xref: EMBL:BC032298 xref: EMBL:BC064913 xref: EMBL:DQ314886 xref: HGNC:HGNC:18838 xref: UniGene:Hs.466937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057979 ! IASPP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011821 name: ZNF107_human def: "Zinc finger protein 107 gene" [UniProtKB:Q9UII5] synonym: "ZFD25" EXACT [UniProtKB:Q9UII5] synonym: "ZNF588" EXACT [UniProtKB:Q9UII5] xref: EMBL:AB027251 xref: EMBL:BC047243 xref: HGNC:HGNC:12887 xref: UniGene:Hs.50216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059163 ! ZN107_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011822 name: LIMS1_human def: "LIM and senescent cell antigen-like-containing domain protein 1 gene" [UniProtKB:P48059] synonym: "PINCH" EXACT [UniProtKB:P48059] synonym: "PINCH1" EXACT [UniProtKB:P48059] xref: EMBL:AC010095 xref: EMBL:BC005341 xref: EMBL:U09284 xref: HGNC:HGNC:6616 xref: UniGene:Hs.597715 xref: UniGene:Hs.613268 xref: UniGene:Hs.655316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062873 ! LIMS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011831 name: RALGPS1_human def: "Ras-specific guanine nucleotide-releasing factor RalGPS1 gene" [UniProtKB:Q5JS13] synonym: "KIAA0351" EXACT [UniProtKB:Q5JS13] synonym: "RALGEF2" EXACT [UniProtKB:Q5JS13] xref: EMBL:AB002349 xref: EMBL:AF221098 xref: EMBL:AL160169 xref: EMBL:AL356862 xref: EMBL:AL357623 xref: EMBL:AL450263 xref: EMBL:BC019329 xref: EMBL:BC032372 xref: EMBL:BC033708 xref: EMBL:CH471090 xref: HGNC:HGNC:16851 xref: UniGene:Hs.696056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037997 ! Q5JT61_HUMAN relationship: codes_for CCO:B0038000 ! Q5JS12_HUMAN relationship: codes_for CCO:B0048898 ! RGPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011838 name: HOXA-9_human def: "HOXA-9A gene" [UniProtKB:O75805] xref: EMBL:U81511 xref: HGNC:HGNC:5109 xref: UniGene:Hs.659350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036822 ! O75805_HUMAN relationship: codes_for CCO:B0054669 ! O75806_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011846 name: PMS2L5_human def: "Postmeiotic segregation increased 2-like protein 5 gene" [UniProtKB:A8MQ11] synonym: "PMS4" EXACT [UniProtKB:A8MQ11] synonym: "PMS7" EXACT [UniProtKB:A8MQ11] xref: EMBL:AC004166 xref: EMBL:AC006014 xref: EMBL:BC027480 xref: EMBL:BC052588 xref: EMBL:D38436 xref: EMBL:D38502 xref: HGNC:HGNC:9130 xref: UniGene:Hs.292996 xref: UniGene:Hs.647025 xref: UniGene:Hs.662458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025452 ! Q15157_HUMAN relationship: codes_for CCO:B0048735 ! PM2L5_HUMAN relationship: codes_for CCO:B0053898 ! A6NLR4_HUMAN relationship: codes_for CCO:B0057217 ! Q7Z7L0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011848 name: HOX B6_human def: "HOX B6 protein gene" [UniProtKB:Q16124] xref: EMBL:S69023 xref: HGNC:HGNC:5117 xref: UniGene:Hs.98428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036835 ! Q16124_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011849 name: PMS5_human def: "PMS5 protein gene" [UniProtKB:Q16603] synonym: "hPMS5" EXACT [UniProtKB:Q16603] xref: EMBL:D38437 xref: EMBL:D38498 xref: HGNC:HGNC:9128 xref: UniGene:Hs.436034 xref: UniGene:Hs.659871 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025462 ! Q16603_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011851 name: HMGA2_human def: "High mobility group protein HMGI-C gene" [UniProtKB:P52926] synonym: "HMGIC" EXACT [UniProtKB:P52926] xref: EMBL:AC090673 xref: EMBL:AC107308 xref: EMBL:AY601863 xref: EMBL:AY601865 xref: EMBL:AY601866 xref: EMBL:AY601867 xref: EMBL:L41044 xref: EMBL:L44578 xref: EMBL:L46353 xref: EMBL:U28749 xref: EMBL:U28750 xref: EMBL:U28751 xref: EMBL:U28752 xref: EMBL:U28753 xref: EMBL:U28754 xref: EMBL:X92518 xref: EMBL:Z31595 xref: HGNC:HGNC:5009 xref: UniGene:Hs.505924 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0036665 ! Q1M183_HUMAN relationship: codes_for CCO:B0041249 ! HMGA2_HUMAN relationship: codes_for CCO:B0056191 ! Q1M182_HUMAN relationship: codes_for CCO:B0056192 ! Q1M186_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011859 name: HLA-DRB3_human def: "HLA class II histocompatibility antigen, DRB3-2 beta chain precursor gene" [UniProtKB:P01913] synonym: "HLA-DR3B" EXACT [UniProtKB:P01913] xref: EMBL:A06800 xref: EMBL:AF148518 xref: EMBL:AF152845 xref: EMBL:AF177216 xref: EMBL:AF192258 xref: EMBL:AF192259 xref: EMBL:AJ001255 xref: EMBL:M17380 xref: EMBL:U36826 xref: EMBL:V00522 xref: EMBL:X95760 xref: EMBL:Y10180 xref: HGNC:HGNC:4951 xref: UniGene:Hs.534322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054858 ! 2B32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011867 name: ZNF714_human def: "Zinc finger protein 714 gene" [UniProtKB:Q96N38] xref: EMBL:AK056006 xref: EMBL:AL834415 xref: EMBL:BC037782 xref: EMBL:BC050468 xref: HGNC:HGNC:27124 xref: UniGene:Hs.466291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048593 ! ZN714_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011869 name: MYO9B variant protein_human def: "MYO9B variant protein gene" [UniProtKB:Q4LE74] xref: EMBL:AB209997 xref: HGNC:HGNC:7609 xref: UniGene:Hs.123198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031117 ! Q4LE74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011888 name: LRP2_human def: "Low-density lipoprotein receptor-related protein 2 precursor gene" [UniProtKB:P98164] xref: EMBL:AC007556 xref: EMBL:AC008178 xref: EMBL:S73145 xref: EMBL:U04441 xref: EMBL:U33837 xref: HGNC:HGNC:6694 xref: UniGene:Hs.657729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055671 ! LRP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011890 name: PREX2_human def: "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein gene" [UniProtKB:Q70Z35] synonym: "DEPDC2" EXACT [UniProtKB:Q70Z35] xref: EMBL:AC011853 xref: EMBL:AC103783 xref: EMBL:AC104416 xref: EMBL:AJ437636 xref: EMBL:AK023049 xref: EMBL:AK024079 xref: EMBL:AY508996 xref: EMBL:AY508997 xref: EMBL:BK005160 xref: EMBL:BK005161 xref: HGNC:HGNC:22950 xref: UniGene:Hs.591867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037018 ! PREX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011893 name: EP3e_human def: "EP3e protein gene" [UniProtKB:Q5CZ59] xref: EMBL:D86096 xref: HGNC:HGNC:9595 xref: UniGene:Hs.445000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037230 ! Q5CZ59_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011894 name: EP3f_human def: "EP3f protein (Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_a) gene" [UniProtKB:Q5CZ60] synonym: "hCG_1811960" EXACT [UniProtKB:Q5CZ60] synonym: "PTGER3" EXACT [UniProtKB:Q5CZ60] xref: EMBL:CH471059 xref: EMBL:D86096 xref: UniGene:Hs.445000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037228 ! Q5CZ60_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011896 name: EP3-V_human def: "EP3-V protein (Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_k) gene" [UniProtKB:Q5CZ62] synonym: "hCG_1811960" EXACT [UniProtKB:Q5CZ62] synonym: "PTGER3" EXACT [UniProtKB:Q5CZ62] xref: EMBL:CH471059 xref: EMBL:D86096 xref: UniGene:Hs.445000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0037231 ! Q5CZ62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011940 name: DKFZp686H1726_human def: "Putative uncharacterized protein DKFZp686H1726 gene" [UniProtKB:Q68DX8] xref: EMBL:CR749236 xref: HGNC:HGNC:13875 xref: UniGene:Hs.656280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015718 ! Q68DX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011946 name: LOC441259_human def: "LOC441259 protein gene" [UniProtKB:Q6DHX9] xref: EMBL:BC075816 xref: UniGene:Hs.292996 xref: UniGene:Hs.662458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025467 ! Q6DHX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011972 name: DKFZp686J1569_human def: "Putative uncharacterized protein DKFZp686J1569 gene" [UniProtKB:Q7Z3Q2] xref: EMBL:BX537558 xref: HGNC:HGNC:9122 xref: UniGene:Hs.632637 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025465 ! Q7Z3Q2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0011983 name: DKFZp434K202_human def: "Putative uncharacterized protein DKFZp434K202 gene" [UniProtKB:Q8NDK2] xref: EMBL:AL833955 xref: HGNC:HGNC:21036 xref: UniGene:Hs.697107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0038153 ! Q8NDK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012009 name: HOXB1_human def: "Homeobox protein Hox-B1 gene" [UniProtKB:P14653] synonym: "HOX2I" EXACT [UniProtKB:P14653] xref: EMBL:X16666 xref: HGNC:HGNC:5111 xref: UniGene:Hs.99992 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055028 ! HXB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012897 name: EXOSC2_human def: "Exosome complex exonuclease RRP4 gene" [UniProtKB:Q13868] synonym: "RRP4" EXACT [UniProtKB:Q13868] xref: EMBL:AK001916 xref: EMBL:AK022460 xref: EMBL:BC000747 xref: EMBL:U07561 xref: HGNC:HGNC:17097 xref: UniGene:Hs.654643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039757 ! EXOS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012898 name: FEN1_human def: "Flap endonuclease 1 gene" [UniProtKB:P39748] synonym: "RAD2" EXACT [UniProtKB:P39748] xref: EMBL:AC004770 xref: EMBL:AF523117 xref: EMBL:BC000323 xref: EMBL:L37374 xref: EMBL:X76771 xref: HGNC:HGNC:3650 xref: UniGene:Hs.409065 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039756 ! FEN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012899 name: SLC26A8_human def: "Testis anion transporter 1 gene" [UniProtKB:Q96RN1] synonym: "TAT1" EXACT [UniProtKB:Q96RN1] xref: EMBL:AF314959 xref: EMBL:AF331522 xref: EMBL:AF403499 xref: EMBL:AK057276 xref: EMBL:AL133507 xref: EMBL:BC025408 xref: EMBL:CH471081 xref: EMBL:Z95152 xref: HGNC:HGNC:14468 xref: UniGene:Hs.435836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0035937 ! S26A8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012900 name: UTP18_human def: "U3 small nucleolar RNA-associated protein 18 homolog gene" [UniProtKB:Q9Y5J1] synonym: "CDABP0061" EXACT [UniProtKB:Q9Y5J1] synonym: "CGI-48" EXACT [UniProtKB:Q9Y5J1] synonym: "WDR50" EXACT [UniProtKB:Q9Y5J1] xref: EMBL:AF151806 xref: EMBL:AY007138 xref: EMBL:BC025276 xref: HGNC:HGNC:24274 xref: UniGene:Hs.463456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039758 ! UTP18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012905 name: BIRC6_human def: "Baculoviral IAP repeat-containing protein 6 gene" [UniProtKB:Q9NR09] synonym: "KIAA1289" EXACT [UniProtKB:Q9NR09] xref: EMBL:AB033115 xref: EMBL:AF265555 xref: HGNC:HGNC:13516 xref: UniGene:Hs.150107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039811 ! BIRC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012908 name: KRT10_human def: "Keratin, type I cytoskeletal 10 gene" [UniProtKB:P13645] synonym: "KPP" EXACT [UniProtKB:P13645] xref: EMBL:BC034697 xref: EMBL:J04029 xref: EMBL:L20218 xref: EMBL:L20219 xref: EMBL:M19156 xref: EMBL:M77663 xref: EMBL:X14487 xref: HGNC:HGNC:6413 xref: UniGene:Hs.99936 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023715 ! K1C10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012911 name: KRT16_human def: "Keratin, type I cytoskeletal 16 gene" [UniProtKB:P08779] synonym: "KRT16A" EXACT [UniProtKB:P08779] xref: EMBL:AF061809 xref: EMBL:AF061812 xref: EMBL:BC039169 xref: EMBL:M28432 xref: EMBL:M28433 xref: EMBL:M28434 xref: EMBL:M28435 xref: EMBL:M28436 xref: EMBL:M28437 xref: EMBL:M28438 xref: EMBL:M28439 xref: EMBL:S78514 xref: EMBL:S79867 xref: HGNC:HGNC:6423 xref: UniGene:Hs.655160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023704 ! K1C16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012913 name: KRT20_human def: "Keratin, type I cytoskeletal 20 gene" [UniProtKB:P35900] xref: EMBL:BC031559 xref: EMBL:X73501 xref: EMBL:X73502 xref: HGNC:HGNC:20412 xref: UniGene:Hs.84905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023749 ! K1C20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012929 name: KLK6_human def: "Kallikrein-6 precursor gene" [UniProtKB:Q92876] synonym: "PRSS18" EXACT [UniProtKB:Q92876] synonym: "PRSS9" EXACT [UniProtKB:Q92876] xref: EMBL:AC011483 xref: EMBL:AF013988 xref: EMBL:AF149289 xref: EMBL:AF243527 xref: EMBL:AK314897 xref: EMBL:AY318867 xref: EMBL:AY318868 xref: EMBL:AY318869 xref: EMBL:AY318870 xref: EMBL:BC015525 xref: EMBL:BT006852 xref: EMBL:CH471135 xref: EMBL:D78203 xref: EMBL:DQ223012 xref: EMBL:U62801 xref: HGNC:HGNC:6367 xref: UniGene:Hs.79361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039862 ! KLK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012931 name: KLK8_human def: "Kallikrein-8 precursor gene" [UniProtKB:O60259] synonym: "NRPN" EXACT [UniProtKB:O60259] synonym: "PRSS19" EXACT [UniProtKB:O60259] synonym: "TADG14" EXACT [UniProtKB:O60259] synonym: "UNQ283/PRO322" EXACT [UniProtKB:O60259] xref: EMBL:AB008390 xref: EMBL:AB008927 xref: EMBL:AB009849 xref: EMBL:AB010780 xref: EMBL:AB012761 xref: EMBL:AC011473 xref: EMBL:AC011483 xref: EMBL:AF055982 xref: EMBL:AF095742 xref: EMBL:AF095743 xref: EMBL:AF243527 xref: EMBL:AF251125 xref: EMBL:AY359036 xref: EMBL:AY563055 xref: EMBL:AY563056 xref: EMBL:AY563057 xref: EMBL:AY563058 xref: EMBL:AY563059 xref: EMBL:AY563060 xref: EMBL:AY563061 xref: EMBL:AY563062 xref: EMBL:AY563063 xref: EMBL:AY563064 xref: EMBL:AY563065 xref: EMBL:AY563066 xref: EMBL:AY563067 xref: EMBL:BC040887 xref: EMBL:CH471135 xref: EMBL:DQ267420 xref: HGNC:HGNC:6369 xref: UniGene:Hs.104570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039858 ! KLK8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012944 name: RHEB_human def: "GTP-binding protein Rheb precursor gene" [UniProtKB:Q15382] synonym: "RHEB2" EXACT [UniProtKB:Q15382] xref: EMBL:AC005996 xref: EMBL:AF148645 xref: EMBL:AF493921 xref: EMBL:BC016155 xref: EMBL:BC107705 xref: EMBL:BT006958 xref: EMBL:D78132 xref: EMBL:Z29677 xref: HGNC:HGNC:10011 xref: UniGene:Hs.283521 xref: UniGene:Hs.568850 xref: UniGene:Hs.647068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039886 ! RHEB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012946 name: TLE4_human def: "Transducin-like enhancer protein 4 gene" [UniProtKB:Q04727] synonym: "KIAA1261" EXACT [UniProtKB:Q04727] xref: EMBL:AB033087 xref: EMBL:AL162059 xref: EMBL:AL353813 xref: EMBL:AL358975 xref: EMBL:AL445252 xref: EMBL:BC045650 xref: EMBL:BC059405 xref: EMBL:M99439 xref: HGNC:HGNC:11840 xref: UniGene:Hs.444213 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016924 ! TLE4_HUMAN relationship: codes_for CCO:B0016926 ! A6NIY7_HUMAN relationship: codes_for CCO:B0039910 ! A8MSP9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012947 name: TLE6_human def: "Transducin-like enhancer protein 6 gene" [UniProtKB:Q9H808] xref: EMBL:AK024071 xref: EMBL:BC007215 xref: EMBL:BC020206 xref: HGNC:HGNC:30788 xref: UniGene:Hs.334507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039905 ! TLE6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012948 name: TNFRSF13B_human def: "Tumor necrosis factor receptor superfamily member 13B gene" [UniProtKB:O14836] synonym: "TACI" EXACT [UniProtKB:O14836] xref: EMBL:AF023614 xref: EMBL:AY302137 xref: HGNC:HGNC:18153 xref: UniGene:Hs.158341 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039914 ! TR13B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012954 name: GUCA1B_human def: "Guanylyl cyclase-activating protein 2 gene" [UniProtKB:Q9UMX6] synonym: "GCAP2" EXACT [UniProtKB:Q9UMX6] xref: EMBL:AF173227 xref: EMBL:AF173228 xref: EMBL:AF173229 xref: EMBL:AL096814 xref: HGNC:HGNC:4679 xref: UniGene:Hs.446529 xref: UniGene:Hs.654550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059244 ! GUC1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012992 name: CREBL2_human def: "cAMP-responsive element-binding protein-like 2 gene" [UniProtKB:O60519] xref: EMBL:AF039081 xref: EMBL:BC104873 xref: EMBL:BC106052 xref: EMBL:BC112157 xref: EMBL:CH471094 xref: EMBL:CR542250 xref: HGNC:HGNC:2350 xref: UniGene:Hs.591156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039945 ! CRBL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012994 name: FSD1_human def: "Fibronectin type III and SPRY domain-containing protein 1 gene" [UniProtKB:Q9BTV5] synonym: "GLFND" EXACT [UniProtKB:Q9BTV5] synonym: "MIR1" EXACT [UniProtKB:Q9BTV5] synonym: "VLP27" EXACT [UniProtKB:Q9BTV5] xref: EMBL:AF316829 xref: EMBL:AK021750 xref: EMBL:AY032617 xref: EMBL:BC003124 xref: HGNC:HGNC:13745 xref: UniGene:Hs.28144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039949 ! FSD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012995 name: NPAT_human def: "Protein NPAT gene" [UniProtKB:Q14207] synonym: "CAND3" EXACT [UniProtKB:Q14207] synonym: "E14" EXACT [UniProtKB:Q14207] xref: EMBL:AK290020 xref: EMBL:AK291687 xref: EMBL:BC040356 xref: EMBL:BC050561 xref: EMBL:D83243 xref: EMBL:D89854 xref: EMBL:U58852 xref: EMBL:X97186 xref: HGNC:HGNC:7896 xref: UniGene:Hs.171061 xref: UniGene:Hs.367437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039946 ! NPAT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012996 name: STRA8_human def: "Stimulated by retinoic acid gene 8 protein homolog gene" [UniProtKB:Q7Z7C7] xref: EMBL:AF513502 xref: EMBL:CH236950 xref: EMBL:CH471070 xref: HGNC:HGNC:30653 xref: UniGene:Hs.592279 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039947 ! STRA8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0012997 name: ZFP42_human def: "Zinc finger protein 42 homolog gene" [UniProtKB:Q96MM3] synonym: "REX1" EXACT [UniProtKB:Q96MM3] synonym: "ZNF754" EXACT [UniProtKB:Q96MM3] xref: EMBL:AF450454 xref: EMBL:AK056719 xref: EMBL:AY429593 xref: HGNC:HGNC:30949 xref: UniGene:Hs.335787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039948 ! ZFP42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013022 name: PPP1R16A_human def: "Protein phosphatase 1 regulatory subunit 16A gene" [UniProtKB:Q96I34] synonym: "MYPT3" EXACT [UniProtKB:Q96I34] xref: EMBL:AK090471 xref: EMBL:BC007854 xref: EMBL:BC049841 xref: EMBL:BC053506 xref: EMBL:BT006845 xref: HGNC:HGNC:14941 xref: UniGene:Hs.521937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039979 ! PP16A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013027 name: GNPAT_human def: "Dihydroxyacetone phosphate acyltransferase gene" [UniProtKB:O15228] synonym: "DAPAT" EXACT [UniProtKB:O15228] synonym: "DHAPAT" EXACT [UniProtKB:O15228] xref: EMBL:AF043937 xref: EMBL:AF218223 xref: EMBL:AF218224 xref: EMBL:AF218225 xref: EMBL:AF218226 xref: EMBL:AF218227 xref: EMBL:AF218228 xref: EMBL:AF218229 xref: EMBL:AF218230 xref: EMBL:AF218231 xref: EMBL:AF218232 xref: EMBL:AF218233 xref: EMBL:AJ002190 xref: EMBL:AL117352 xref: EMBL:AL137801 xref: EMBL:BC000450 xref: HGNC:HGNC:4416 xref: UniGene:Hs.498028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040018 ! GNPAT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013031 name: YY2_human def: "Transcription factor YY2 gene" [UniProtKB:O15391] synonym: "ZNF631" EXACT [UniProtKB:O15391] xref: EMBL:AY567472 xref: EMBL:CH471074 xref: EMBL:U73479 xref: HGNC:HGNC:31684 xref: UniGene:Hs.673601 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041843 ! TYY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013082 name: CASP1_human def: "Caspase-1 precursor gene" [UniProtKB:P29466] synonym: "IL1BC" EXACT [UniProtKB:P29466] synonym: "IL1BCE" EXACT [UniProtKB:P29466] xref: EMBL:AB102878 xref: EMBL:AK223503 xref: EMBL:AY660536 xref: EMBL:BC041689 xref: EMBL:BC062327 xref: EMBL:M87507 xref: EMBL:U13697 xref: EMBL:U13698 xref: EMBL:U13699 xref: EMBL:U13700 xref: EMBL:X65019 xref: HGNC:HGNC:1499 xref: UniGene:Hs.2490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040467 ! CASP1_HUMAN relationship: codes_for CCO:B0040469 ! Q5FBZ0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013083 name: CASP4_human def: "Caspase-4 precursor gene" [UniProtKB:P49662] synonym: "ICH2" EXACT [UniProtKB:P49662] xref: EMBL:BC017839 xref: EMBL:U25804 xref: EMBL:U28014 xref: EMBL:Z48810 xref: HGNC:HGNC:1505 xref: UniGene:Hs.138378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040471 ! CASP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013084 name: CASP5_human def: "Caspase-5 precursor gene" [UniProtKB:P51878] synonym: "ICH3" EXACT [UniProtKB:P51878] xref: EMBL:AP001153 xref: EMBL:U28015 xref: EMBL:X94993 xref: HGNC:HGNC:1506 xref: UniGene:Hs.213327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040484 ! CASP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013085 name: CASP12_human def: "Inactive caspase-12 gene" [UniProtKB:Q6UXS9] synonym: "UNQ9415/PRO34398" EXACT [UniProtKB:Q6UXS9] xref: EMBL:AF464191 xref: EMBL:AF464192 xref: EMBL:AF464193 xref: EMBL:AF464194 xref: EMBL:AF464195 xref: EMBL:AF486844 xref: EMBL:AF486845 xref: EMBL:AF486846 xref: EMBL:AF486847 xref: EMBL:AY358222 xref: HGNC:HGNC:19004 xref: UniGene:Hs.476989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040485 ! CASPC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013099 name: ICEBERG_human def: "Caspase-1 inhibitor Iceberg gene" [UniProtKB:P57730] synonym: "UNQ5804/PRO19611" EXACT [UniProtKB:P57730] xref: EMBL:AF208005 xref: EMBL:AY358231 xref: UniGene:Hs.56279 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040474 ! ICBR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013100 name: KPNA4_human def: "Importin subunit alpha-4 gene" [UniProtKB:O00629] synonym: "QIP1" EXACT [UniProtKB:O00629] xref: EMBL:AB002533 xref: EMBL:BC028691 xref: EMBL:BC034493 xref: EMBL:U93240 xref: EMBL:Y12393 xref: HGNC:HGNC:6397 xref: UniGene:Hs.288193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040253 ! IMA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013101 name: ITSN1_human def: "Intersectin-1 gene" [UniProtKB:Q15811] synonym: "ITSN" EXACT [UniProtKB:Q15811] synonym: "SH3D1A" EXACT [UniProtKB:Q15811] xref: EMBL:AF064243 xref: EMBL:AF064244 xref: EMBL:AF064245 xref: EMBL:AF064246 xref: EMBL:AF064247 xref: EMBL:AF114487 xref: EMBL:AF114488 xref: EMBL:AF180522 xref: EMBL:AY605091 xref: EMBL:AY605092 xref: EMBL:BC116185 xref: EMBL:U61166 xref: HGNC:HGNC:6183 xref: UniGene:Hs.160324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027932 ! Q6J1T2_HUMAN relationship: codes_for CCO:B0027933 ! Q6J1T1_HUMAN relationship: codes_for CCO:B0027936 ! Q14BD4_HUMAN relationship: codes_for CCO:B0027945 ! ITSN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013103 name: MDN1_human def: "Midasin gene" [UniProtKB:Q9NU22] synonym: "KIAA0301" EXACT [UniProtKB:Q9NU22] xref: EMBL:AB002299 xref: EMBL:AF503925 xref: EMBL:AL096678 xref: EMBL:AL158813 xref: EMBL:AL353692 xref: HGNC:HGNC:18302 xref: UniGene:Hs.529948 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040425 ! MDN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013104 name: MOAP1_human def: "Modulator of apoptosis 1 gene" [UniProtKB:Q96BY2] synonym: "PNMA4" EXACT [UniProtKB:Q96BY2] xref: EMBL:AF305550 xref: EMBL:AK024029 xref: EMBL:BC015044 xref: HGNC:HGNC:16658 xref: UniGene:Hs.24719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021834 ! MOAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013108 name: MYO1F_human def: "Myosin-If gene" [UniProtKB:O00160] xref: EMBL:AJ310570 xref: EMBL:AK092877 xref: EMBL:BC028071 xref: EMBL:X98411 xref: HGNC:HGNC:7600 xref: UniGene:Hs.465818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040367 ! MYO1F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013113 name: PGK1_human def: "Phosphoglycerate kinase 1 gene" [UniProtKB:P00558] synonym: "MIG10" EXACT [UniProtKB:P00558] synonym: "OK/SW-cl.110" EXACT [UniProtKB:P00558] synonym: "PGKA" EXACT [UniProtKB:P00558] xref: EMBL:AB062432 xref: EMBL:AL049589 xref: EMBL:AY423725 xref: EMBL:BC023234 xref: EMBL:BC103752 xref: EMBL:BC104837 xref: EMBL:BC113568 xref: EMBL:CR456716 xref: EMBL:L00160 xref: EMBL:M11958 xref: EMBL:M11959 xref: EMBL:M11960 xref: EMBL:M11961 xref: EMBL:M11962 xref: EMBL:M11963 xref: EMBL:M11964 xref: EMBL:M11965 xref: EMBL:M11966 xref: EMBL:M11967 xref: EMBL:M11968 xref: EMBL:M34017 xref: EMBL:V00572 xref: HGNC:HGNC:8896 xref: UniGene:Hs.701989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040243 ! PGK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013119 name: GART_human def: "Trifunctional purine biosynthetic protein adenosine-3 gene" [UniProtKB:P22102] synonym: "PGFT" EXACT [UniProtKB:P22102] synonym: "PRGS" EXACT [UniProtKB:P22102] xref: EMBL:AF008653 xref: EMBL:BC038958 xref: EMBL:M32082 xref: EMBL:X54199 xref: HGNC:HGNC:4163 xref: UniGene:Hs.473648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021425 ! PUR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013120 name: MTRF1_human def: "Peptide chain release factor 1, mitochondrial precursor gene" [UniProtKB:O75570] xref: EMBL:AF072934 xref: EMBL:AL354696 xref: EMBL:BC042196 xref: HGNC:HGNC:7469 xref: UniGene:Hs.382176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040310 ! RF1M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013121 name: RPS14_human def: "40S ribosomal protein S14 gene" [UniProtKB:P62263] synonym: "PRO2640" EXACT [UniProtKB:P62263] xref: EMBL:AF116710 xref: EMBL:BC001126 xref: EMBL:BC003401 xref: EMBL:BC006784 xref: EMBL:BC020515 xref: EMBL:BC091474 xref: EMBL:M13934 xref: HGNC:HGNC:10387 xref: UniGene:Hs.381126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040516 ! RS14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013125 name: SYT17_human def: "Synaptotagmin-17 gene" [UniProtKB:Q9BSW7] xref: EMBL:AC003003 xref: EMBL:AF220560 xref: EMBL:BC004518 xref: EMBL:CH471186 xref: HGNC:HGNC:24119 xref: UniGene:Hs.258326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040086 ! SYT17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013126 name: SYT1_human def: "Synaptotagmin-1 gene" [UniProtKB:P21579] synonym: "SVP65" EXACT [UniProtKB:P21579] synonym: "SYT" EXACT [UniProtKB:P21579] xref: EMBL:BC058917 xref: EMBL:M55047 xref: HGNC:HGNC:11509 xref: UniGene:Hs.310545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040103 ! SYT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013129 name: SYT5_human def: "Synaptotagmin-5 gene" [UniProtKB:O00445] xref: EMBL:BC046157 xref: EMBL:X96783 xref: HGNC:HGNC:11513 xref: UniGene:Hs.631566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040093 ! SYT5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013134 name: USP8_human def: "Ubiquitin carboxyl-terminal hydrolase 8 gene" [UniProtKB:P40818] synonym: "KIAA0055" EXACT [UniProtKB:P40818] synonym: "UBPY" EXACT [UniProtKB:P40818] xref: EMBL:BC038801 xref: EMBL:BC051345 xref: EMBL:BC110590 xref: EMBL:BX537420 xref: EMBL:D29956 xref: HGNC:HGNC:12631 xref: UniGene:Hs.644563 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040082 ! UBP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013139 name: mih1/Tx_human def: "Mih1/Tx protein gene" [UniProtKB:O95601] xref: EMBL:U28979 xref: HGNC:HGNC:1505 xref: UniGene:Hs.138378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040476 ! O95601_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013152 name: COP1_human def: "Caspase-1 inhibitor COP gene" [UniProtKB:Q5EG05] synonym: "COP" EXACT [UniProtKB:Q5EG05] xref: EMBL:AF367017 xref: EMBL:AK311902 xref: EMBL:AY885669 xref: EMBL:BC117478 xref: EMBL:BC117480 xref: EMBL:CH471065 xref: UniGene:Hs.348365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040491 ! COP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013157 name: INCA_human def: "Caspase-1 inhibitor INCA gene" [UniProtKB:Q5XLA6] xref: EMBL:AY761064 xref: UniGene:Hs.44102 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040472 ! INCA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013372 name: CHPF_human def: "Chondroitin sulfate synthase 2 gene" [UniProtKB:Q8IZ52] synonym: "CSS2" EXACT [UniProtKB:Q8IZ52] synonym: "UNQ651/PRO1281" EXACT [UniProtKB:Q8IZ52] xref: EMBL:AB086063 xref: EMBL:AB095813 xref: EMBL:AC009955 xref: EMBL:AK026331 xref: EMBL:AL136814 xref: EMBL:AY358403 xref: EMBL:BC008878 xref: EMBL:BC021223 xref: EMBL:BC023531 xref: HGNC:HGNC:24291 xref: UniGene:Hs.516711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006320 ! CHSS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013373 name: CUX1_human def: "Homeobox protein cut-like 1 gene" [UniProtKB:P39880] synonym: "CUTL1" EXACT [UniProtKB:P39880] xref: EMBL:AF047825 xref: EMBL:BC066592 xref: EMBL:M74099 xref: HGNC:HGNC:2557 xref: UniGene:Hs.654389 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040687 ! CUX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013374 name: DSCC1_human def: "Sister chromatid cohesion protein DCC1 gene" [UniProtKB:Q9BVC3] synonym: "DCC1" EXACT [UniProtKB:Q9BVC3] synonym: "UNQ9337/PRO34008" EXACT [UniProtKB:Q9BVC3] xref: EMBL:AK054585 xref: EMBL:AY358866 xref: EMBL:BC001316 xref: EMBL:BC001531 xref: HGNC:HGNC:24453 xref: UniGene:Hs.315167 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0039950 ! DCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013375 name: GABPB1_human def: "GA-binding protein subunit beta-1 gene" [UniProtKB:Q06547] synonym: "E4TF1B" EXACT [UniProtKB:Q06547] synonym: "GABPB" EXACT [UniProtKB:Q06547] synonym: "GABPB2" EXACT [UniProtKB:Q06547] xref: EMBL:BC016910 xref: EMBL:BC036080 xref: EMBL:BC050702 xref: EMBL:BT006652 xref: EMBL:D13316 xref: EMBL:D13317 xref: EMBL:U13045 xref: EMBL:U13046 xref: EMBL:U13047 xref: EMBL:U13048 xref: HGNC:HGNC:4074 xref: UniGene:Hs.654350 xref: UniGene:Hs.659360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0040683 ! GABP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013376 name: HIST2H4B_human def: "Histone H4 gene" [UniProtKB:P62805] synonym: "H4/O" EXACT [UniProtKB:P62805] synonym: "H4FO" EXACT [UniProtKB:P62805] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005700 ! H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013377 name: HTT_human def: "Huntingtin gene" [UniProtKB:P42858] synonym: "HD" EXACT [UniProtKB:P42858] synonym: "IT15" EXACT [UniProtKB:P42858] xref: EMBL:AB016794 xref: EMBL:L12392 xref: EMBL:L20431 xref: EMBL:L27350 xref: EMBL:L27351 xref: EMBL:L27352 xref: EMBL:L27353 xref: EMBL:L27354 xref: EMBL:L34020 xref: EMBL:Z49154 xref: EMBL:Z49155 xref: EMBL:Z49208 xref: EMBL:Z49769 xref: EMBL:Z68756 xref: EMBL:Z69649 xref: HGNC:HGNC:4851 xref: UniGene:Hs.518450 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005407 ! HD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013383 name: CCNDBP1_human def: "Cyclin-D1-binding protein 1 gene" [UniProtKB:O95273] synonym: "DIP1" EXACT [UniProtKB:O95273] synonym: "GCIP" EXACT [UniProtKB:O95273] synonym: "HHM" EXACT [UniProtKB:O95273] xref: EMBL:AF082569 xref: EMBL:AF087852 xref: EMBL:AF113535 xref: EMBL:AF132034 xref: EMBL:AF246144 xref: EMBL:AK075146 xref: EMBL:AK075296 xref: EMBL:AK128849 xref: EMBL:AK290665 xref: EMBL:AK290707 xref: EMBL:BC009689 xref: EMBL:CH471125 xref: EMBL:CR450331 xref: HGNC:HGNC:1587 xref: UniGene:Hs.36794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041241 ! CCDB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013384 name: CINP_human def: "Cyclin-dependent kinase 2-interacting protein gene" [UniProtKB:Q9BW66] xref: EMBL:AF228148 xref: EMBL:AF228149 xref: EMBL:AK056112 xref: EMBL:BC000600 xref: EMBL:CH471061 xref: EMBL:CR457178 xref: UniGene:Hs.129634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041266 ! CINP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013385 name: NCAPH2_human def: "Condensin-2 complex subunit H2 gene" [UniProtKB:Q6IBW4] synonym: "CAPH2" EXACT [UniProtKB:Q6IBW4] xref: EMBL:AL021682 xref: EMBL:BC000473 xref: EMBL:BC001298 xref: EMBL:BC001509 xref: EMBL:BC001833 xref: EMBL:BC001937 xref: EMBL:BC009441 xref: EMBL:BC014939 xref: EMBL:CH471138 xref: EMBL:CR456604 xref: EMBL:U62317 xref: HGNC:HGNC:25071 xref: UniGene:Hs.180903 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041259 ! CNDH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013387 name: DMTF1_human def: "Cyclin-D-binding Myb-like transcription factor 1 gene" [UniProtKB:Q9Y222] synonym: "DMP1" EXACT [UniProtKB:Q9Y222] xref: EMBL:AB209230 xref: EMBL:AC005076 xref: EMBL:AF084530 xref: EMBL:AF202144 xref: EMBL:AF202145 xref: EMBL:AK126664 xref: EMBL:BC007418 xref: EMBL:BC007447 xref: EMBL:BC029370 xref: EMBL:BC070064 xref: EMBL:CH471091 xref: HGNC:HGNC:14603 xref: UniGene:Hs.654981 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041267 ! DMTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013388 name: E4F1_human def: "Transcription factor E4F1 gene" [UniProtKB:Q66K89] synonym: "E4F" EXACT [UniProtKB:Q66K89] xref: EMBL:AK290329 xref: EMBL:BC080524 xref: EMBL:CH471112 xref: EMBL:U87269 xref: HGNC:HGNC:3121 xref: UniGene:Hs.513268 xref: UniGene:Hs.615283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041257 ! E4F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013389 name: ERCC6L_human def: "DNA excision repair protein ERCC-6-like gene" [UniProtKB:Q2NKX8] synonym: "PICH" EXACT [UniProtKB:Q2NKX8] xref: EMBL:AK000112 xref: EMBL:AK074719 xref: EMBL:AY121802 xref: EMBL:BC008808 xref: EMBL:BC111486 xref: EMBL:EU069463 xref: HGNC:HGNC:20794 xref: UniGene:Hs.47558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041256 ! ERC6L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013390 name: GUSBP1_human def: "Putative beta-glucuronidase-like protein SMA3 gene" [UniProtKB:Q15486] synonym: "SMA3" EXACT [UniProtKB:Q15486] xref: EMBL:AK289832 xref: EMBL:AK315849 xref: EMBL:AL009030 xref: EMBL:BC002622 xref: EMBL:BC050737 xref: EMBL:BT006760 xref: EMBL:X83299 xref: HGNC:HGNC:13670 xref: UniGene:Hs.529793 xref: UniGene:Hs.654587 xref: UniGene:Hs.654588 xref: UniGene:Hs.675815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041277 ! GUSP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013391 name: MAPK1IP1L_human def: "MAPK-interacting and spindle-stabilizing protein-like gene" [UniProtKB:Q8NDC0] synonym: "C14orf32" EXACT [UniProtKB:Q8NDC0] xref: EMBL:AL139316 xref: EMBL:AL834285 xref: EMBL:BC015621 xref: HGNC:HGNC:19840 xref: UniGene:Hs.594338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041276 ! MISSL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013392 name: MTBP_human def: "Mdm2-binding protein gene" [UniProtKB:Q96DY7] xref: EMBL:AK022122 xref: EMBL:BC013136 xref: EMBL:CH471060 xref: HGNC:HGNC:7417 xref: UniGene:Hs.657656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041265 ! MTBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013393 name: PRKCDBP_human def: "Protein kinase C delta-binding protein gene" [UniProtKB:Q969G5] synonym: "SRBC" EXACT [UniProtKB:Q969G5] xref: EMBL:AC068733 xref: EMBL:AF339881 xref: EMBL:AF408198 xref: EMBL:BC011585 xref: EMBL:CH471064 xref: HGNC:HGNC:9400 xref: UniGene:Hs.434044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041264 ! PRDBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013394 name: PSMC3_human def: "26S protease regulatory subunit 6A gene" [UniProtKB:P17980] synonym: "TBP1" EXACT [UniProtKB:P17980] xref: EMBL:AK222485 xref: EMBL:BC008713 xref: EMBL:BC073165 xref: EMBL:BC106920 xref: EMBL:BC107804 xref: EMBL:CR456731 xref: EMBL:M34079 xref: HGNC:HGNC:9549 xref: UniGene:Hs.250758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041242 ! PRS6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013395 name: PSMC4_human def: "26S protease regulatory subunit 6B gene" [UniProtKB:P43686] synonym: "MIP224" EXACT [UniProtKB:P43686] synonym: "TBP7" EXACT [UniProtKB:P43686] xref: EMBL:AC007842 xref: EMBL:AF020736 xref: EMBL:AF038965 xref: EMBL:BC000343 xref: EMBL:BC010396 xref: EMBL:BC014488 xref: EMBL:BT007232 xref: EMBL:U27515 xref: HGNC:HGNC:9551 xref: UniGene:Hs.211594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041247 ! PRS6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013396 name: PSMC2_human def: "26S protease regulatory subunit 7 gene" [UniProtKB:P35998] synonym: "MSS1" EXACT [UniProtKB:P35998] xref: EMBL:BC002589 xref: EMBL:D11094 xref: HGNC:HGNC:9548 xref: UniGene:Hs.437366 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041246 ! PRS7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013397 name: PSMC5_human def: "26S protease regulatory subunit 8 gene" [UniProtKB:P62195] synonym: "SUG1" EXACT [UniProtKB:P62195] xref: EMBL:AF035309 xref: EMBL:BC001932 xref: EMBL:BC002367 xref: EMBL:D44467 xref: EMBL:L38810 xref: HGNC:HGNC:9552 xref: UniGene:Hs.79387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041253 ! PRS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013398 name: PSMA2_human def: "Proteasome subunit alpha type-2 gene" [UniProtKB:P25787] synonym: "PSC3" EXACT [UniProtKB:P25787] xref: EMBL:BC002900 xref: EMBL:BC047697 xref: EMBL:D00760 xref: HGNC:HGNC:9531 xref: UniGene:Hs.333786 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041243 ! PSA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013399 name: PSMA4_human def: "Proteasome subunit alpha type-4 gene" [UniProtKB:P25789] synonym: "PSC9" EXACT [UniProtKB:P25789] xref: EMBL:BC005361 xref: EMBL:BC022445 xref: EMBL:BC022817 xref: EMBL:BC047667 xref: EMBL:D00763 xref: HGNC:HGNC:9533 xref: UniGene:Hs.251531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041244 ! PSA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013400 name: PSMA6_human def: "Proteasome subunit alpha type-6 gene" [UniProtKB:P60900] synonym: "PROS27" EXACT [UniProtKB:P60900] xref: EMBL:BC002979 xref: EMBL:BC017882 xref: EMBL:BC022354 xref: EMBL:BC023659 xref: EMBL:BC070137 xref: EMBL:CR456944 xref: EMBL:X59417 xref: EMBL:X61972 xref: HGNC:HGNC:9535 xref: UniGene:Hs.446260 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041251 ! PSA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013401 name: PSMB4_human def: "Proteasome subunit beta type-4 precursor gene" [UniProtKB:P28070] xref: EMBL:AL589764 xref: EMBL:BC000331 xref: EMBL:BC008314 xref: EMBL:BC010088 xref: EMBL:BC010098 xref: EMBL:BC011768 xref: EMBL:BC012168 xref: EMBL:BC017307 xref: EMBL:BC017451 xref: EMBL:BC017486 xref: EMBL:BT006917 xref: EMBL:D26600 xref: EMBL:S71381 xref: HGNC:HGNC:9541 xref: UniGene:Hs.89545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041245 ! PSB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013402 name: PSMD10_human def: "26S proteasome non-ATPase regulatory subunit 10 gene" [UniProtKB:O75832] xref: EMBL:AB009619 xref: EMBL:AL031177 xref: EMBL:BC011960 xref: EMBL:D83197 xref: HGNC:HGNC:9555 xref: UniGene:Hs.522752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041240 ! PSD10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013403 name: PSMD4_human def: "26S proteasome non-ATPase regulatory subunit 4 gene" [UniProtKB:P55036] synonym: "MCB1" EXACT [UniProtKB:P55036] xref: EMBL:AB033605 xref: EMBL:AL391069 xref: EMBL:AL592424 xref: EMBL:BC002365 xref: EMBL:BC072008 xref: EMBL:U24704 xref: EMBL:U51007 xref: EMBL:U72664 xref: HGNC:HGNC:9561 xref: UniGene:Hs.505059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041250 ! PSMD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013404 name: PSMD5_human def: "26S proteasome non-ATPase regulatory subunit 5 gene" [UniProtKB:Q16401] synonym: "KIAA0072" EXACT [UniProtKB:Q16401] xref: EMBL:AL161911 xref: EMBL:BC014478 xref: EMBL:CH471090 xref: EMBL:D31889 xref: EMBL:S79862 xref: HGNC:HGNC:9563 xref: UniGene:Hs.193725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041255 ! PSMD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013405 name: PSMD9_human def: "26S proteasome non-ATPase regulatory subunit 9 gene" [UniProtKB:O00233] xref: EMBL:AB003177 xref: EMBL:BC002383 xref: EMBL:BC004184 xref: EMBL:BC004213 xref: HGNC:HGNC:9567 xref: UniGene:Hs.131151 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041239 ! PSMD9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013406 name: PSME3_human def: "Proteasome activator complex subunit 3 gene" [UniProtKB:P61289] xref: EMBL:BC001423 xref: EMBL:BC002684 xref: EMBL:BC008020 xref: EMBL:BT019386 xref: EMBL:U11292 xref: EMBL:U25756 xref: HGNC:HGNC:9570 xref: UniGene:Hs.152978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041252 ! PSME3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013407 name: PSMF1_human def: "Proteasome inhibitor PI31 subunit gene" [UniProtKB:Q92530] xref: EMBL:AL031665 xref: EMBL:BC126462 xref: EMBL:D88378 xref: HGNC:HGNC:9571 xref: UniGene:Hs.471917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041263 ! PSMF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013408 name: PROTOR1_human def: "Protor-1 gene" [UniProtKB:P85299] synonym: "PP610" EXACT [UniProtKB:P85299] synonym: "PRR5" EXACT [UniProtKB:P85299] xref: EMBL:AF177331 xref: EMBL:AK000192 xref: EMBL:BC016921 xref: EMBL:BK005635 xref: EMBL:BK005636 xref: EMBL:BK005637 xref: EMBL:BK005638 xref: EMBL:BK005639 xref: EMBL:Z93244 xref: EMBL:Z98743 xref: HGNC:HGNC:31682 xref: UniGene:Hs.102336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041254 ! PTOR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013409 name: TMEM90B_human def: "Transmembrane protein 90B gene" [UniProtKB:Q9H7V2] synonym: "C20orf39" EXACT [UniProtKB:Q9H7V2] xref: EMBL:AK024282 xref: EMBL:AL049594 xref: EMBL:AL157413 xref: EMBL:BC030637 xref: EMBL:CR457325 xref: HGNC:HGNC:15885 xref: UniGene:Hs.124638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041279 ! TM90B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013410 name: UBE2E1_human def: "Ubiquitin-conjugating enzyme E2 E1 gene" [UniProtKB:P51965] synonym: "UBCH6" EXACT [UniProtKB:P51965] xref: EMBL:BC009139 xref: EMBL:X92963 xref: HGNC:HGNC:12477 xref: UniGene:Hs.164853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041248 ! UB2E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013411 name: USP22_human def: "Ubiquitin carboxyl-terminal hydrolase 22 gene" [UniProtKB:Q9UPT9] synonym: "KIAA1063" EXACT [UniProtKB:Q9UPT9] synonym: "USP3L" EXACT [UniProtKB:Q9UPT9] xref: EMBL:AB028986 xref: HGNC:HGNC:12621 xref: UniGene:Hs.462492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024005 ! UBP22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013412 name: XAF1_human def: "XIAP-associated factor 1 gene" [UniProtKB:Q6GPH4] synonym: "BIRC4BP" EXACT [UniProtKB:Q6GPH4] synonym: "XIAPAF1" EXACT [UniProtKB:Q6GPH4] xref: EMBL:AK290276 xref: EMBL:AK292710 xref: EMBL:AK292848 xref: EMBL:BC032776 xref: EMBL:BC073156 xref: EMBL:BX649188 xref: EMBL:CH471108 xref: EMBL:EF028165 xref: EMBL:EF028166 xref: EMBL:X99699 xref: HGNC:HGNC:30932 xref: UniGene:Hs.441975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041258 ! XAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013473 name: CHRNE_human def: "Acetylcholine receptor subunit epsilon precursor gene" [UniProtKB:Q04844] synonym: "ACHRE" EXACT [UniProtKB:Q04844] xref: EMBL:AF105999 xref: EMBL:X66403 xref: HGNC:HGNC:1966 xref: UniGene:Hs.654535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042294 ! ACHE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013474 name: CHRNG_human def: "Acetylcholine receptor subunit gamma precursor gene" [UniProtKB:P07510] synonym: "ACHRG" EXACT [UniProtKB:P07510] xref: EMBL:AC092165 xref: EMBL:X01715 xref: EMBL:X01716 xref: EMBL:X01717 xref: EMBL:X01718 xref: EMBL:X01719 xref: EMBL:X01720 xref: EMBL:X01721 xref: EMBL:X04759 xref: HGNC:HGNC:1967 xref: UniGene:Hs.248101 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042293 ! ACHG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013475 name: MC2R_human def: "Adrenocorticotropic hormone receptor gene" [UniProtKB:Q01718] synonym: "ACTHR" EXACT [UniProtKB:Q01718] xref: EMBL:AB065915 xref: EMBL:AY225229 xref: EMBL:BC069074 xref: EMBL:BC094710 xref: EMBL:BC104169 xref: EMBL:BC104170 xref: EMBL:X65633 xref: HGNC:HGNC:6930 xref: UniGene:Hs.248144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030577 ! ACTHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013477 name: MLLT6_human def: "Protein AF-17 gene" [UniProtKB:P55198] synonym: "AF17" EXACT [UniProtKB:P55198] xref: EMBL:AB209633 xref: EMBL:AC006449 xref: EMBL:AK027133 xref: EMBL:AL133659 xref: EMBL:BC007237 xref: EMBL:U07932 xref: HGNC:HGNC:7138 xref: UniGene:Hs.91531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042847 ! AF17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013478 name: GFER_human def: "FAD-linked sulfhydryl oxidase ALR gene" [UniProtKB:P55789] synonym: "ALR" EXACT [UniProtKB:P55789] synonym: "HERV1" EXACT [UniProtKB:P55789] xref: EMBL:AF146394 xref: EMBL:BC002429 xref: EMBL:BC028348 xref: EMBL:U31176 xref: HGNC:HGNC:4236 xref: UniGene:Hs.27184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042007 ! ALR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013479 name: ANK1_human def: "Ankyrin-1 gene" [UniProtKB:P16157] synonym: "ANK" EXACT [UniProtKB:P16157] xref: EMBL:AB209418 xref: EMBL:AC113133 xref: EMBL:AF005213 xref: EMBL:BC030957 xref: EMBL:M28880 xref: EMBL:U50092 xref: EMBL:U50093 xref: EMBL:U50094 xref: EMBL:U50095 xref: EMBL:U50096 xref: EMBL:U50097 xref: EMBL:U50098 xref: EMBL:U50099 xref: EMBL:U50100 xref: EMBL:U50101 xref: EMBL:U50102 xref: EMBL:U50103 xref: EMBL:U50104 xref: EMBL:U50105 xref: EMBL:U50106 xref: EMBL:U50107 xref: EMBL:U50108 xref: EMBL:U50109 xref: EMBL:U50110 xref: EMBL:U50111 xref: EMBL:U50112 xref: EMBL:U50113 xref: EMBL:U50114 xref: EMBL:U50115 xref: EMBL:U50116 xref: EMBL:U50117 xref: EMBL:U50118 xref: EMBL:U50119 xref: EMBL:U50120 xref: EMBL:U50121 xref: EMBL:U50122 xref: EMBL:U50123 xref: EMBL:U50124 xref: EMBL:U50125 xref: EMBL:U50126 xref: EMBL:U50127 xref: EMBL:U50128 xref: EMBL:U50129 xref: EMBL:U50130 xref: EMBL:U50131 xref: EMBL:U50132 xref: EMBL:U50133 xref: EMBL:X16609 xref: HGNC:HGNC:492 xref: UniGene:Hs.654438 xref: UniGene:Hs.667377 xref: UniGene:Hs.680451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041523 ! ANK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013480 name: ANK2_human def: "Ankyrin-2 gene" [UniProtKB:Q01484] xref: EMBL:AC004057 xref: EMBL:AC093617 xref: EMBL:AC093879 xref: EMBL:AC093900 xref: EMBL:BC125235 xref: EMBL:M37123 xref: EMBL:X56957 xref: EMBL:X56958 xref: EMBL:Z26634 xref: HGNC:HGNC:493 xref: UniGene:Hs.620557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041516 ! ANK2_HUMAN relationship: codes_for CCO:B0055797 ! Q08AC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013481 name: ANK3_human def: "Ankyrin-3 gene" [UniProtKB:Q12955] xref: EMBL:AC023904 xref: EMBL:AL592430 xref: EMBL:U13616 xref: HGNC:HGNC:494 xref: UniGene:Hs.499725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041526 ! ANK3_HUMAN relationship: codes_for CCO:B0041532 ! B1AQT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013483 name: APIP_human def: "APAF1-interacting protein gene" [UniProtKB:Q96GX9] synonym: "CGI-29" EXACT [UniProtKB:Q96GX9] xref: EMBL:AF132963 xref: EMBL:BC008440 xref: EMBL:BC009077 xref: EMBL:BC010133 xref: EMBL:BC017594 xref: HGNC:HGNC:17581 xref: UniGene:Hs.447794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042018 ! APIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013486 name: APOL3_human def: "Apolipoprotein L3 gene" [UniProtKB:O95236] xref: EMBL:AF070675 xref: EMBL:AF305227 xref: EMBL:AF324233 xref: EMBL:AF324236 xref: EMBL:AF324237 xref: EMBL:AF324238 xref: EMBL:AY014902 xref: EMBL:AY014903 xref: EMBL:AY014904 xref: EMBL:AY014905 xref: EMBL:AY014906 xref: EMBL:AY014907 xref: EMBL:CR456379 xref: EMBL:Z95114 xref: HGNC:HGNC:14868 xref: UniGene:Hs.474737 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041769 ! APOL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013496 name: BMP10_human def: "Bone morphogenetic protein 10 precursor gene" [UniProtKB:O95393] xref: EMBL:AC097495 xref: EMBL:AF101441 xref: EMBL:BC069080 xref: EMBL:BC101734 xref: EMBL:BC105063 xref: HGNC:HGNC:20869 xref: UniGene:Hs.158317 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042127 ! BMP10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013499 name: BMP6_human def: "Bone morphogenetic protein 6 precursor gene" [UniProtKB:P22004] synonym: "VGR" EXACT [UniProtKB:P22004] xref: EMBL:AL133541 xref: EMBL:AL135778 xref: EMBL:M60315 xref: HGNC:HGNC:1073 xref: UniGene:Hs.285671 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042130 ! BMP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013502 name: BNIPL_human def: "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein gene" [UniProtKB:Q7Z465] xref: EMBL:AF193056 xref: EMBL:AL590133 xref: EMBL:AY033000 xref: EMBL:AY078983 xref: EMBL:AY078984 xref: EMBL:BC027868 xref: EMBL:BC074779 xref: EMBL:BC074780 xref: HGNC:HGNC:16976 xref: UniGene:Hs.591473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041672 ! BNIPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013504 name: BRCC3_human def: "BRCA1/BRCA2-containing complex subunit 3 gene" [UniProtKB:P46736] synonym: "C6.1A" EXACT [UniProtKB:P46736] synonym: "CXorf53" EXACT [UniProtKB:P46736] xref: EMBL:BC002999 xref: EMBL:BC006540 xref: EMBL:S68015 xref: EMBL:X64643 xref: HGNC:HGNC:24185 xref: UniGene:Hs.558537 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042518 ! BRCC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013509 name: CAPN1_human def: "Calpain-1 catalytic subunit gene" [UniProtKB:P07384] synonym: "CANPL1" EXACT [UniProtKB:P07384] xref: EMBL:AY796340 xref: EMBL:BC008751 xref: EMBL:BC017200 xref: EMBL:X04366 xref: HGNC:HGNC:1476 xref: UniGene:Hs.502842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041800 ! CAN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013510 name: CAPN2_human def: "Calpain-2 catalytic subunit precursor gene" [UniProtKB:P17655] synonym: "CANPL2" EXACT [UniProtKB:P17655] xref: EMBL:AF261089 xref: EMBL:AY835586 xref: EMBL:BC007686 xref: EMBL:BC011828 xref: EMBL:BC021303 xref: EMBL:J04700 xref: EMBL:M23254 xref: HGNC:HGNC:1479 xref: UniGene:Hs.350899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041821 ! CAN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013511 name: CAPN5_human def: "Calpain-5 gene" [UniProtKB:O15484] synonym: "NCL3" EXACT [UniProtKB:O15484] xref: EMBL:BC018123 xref: EMBL:U94346 xref: EMBL:Y10552 xref: HGNC:HGNC:1482 xref: UniGene:Hs.248153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041822 ! CAN5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013519 name: CXCL5_human def: "C-X-C motif chemokine 5 precursor gene" [UniProtKB:P42830] synonym: "ENA78" EXACT [UniProtKB:P42830] synonym: "SCYB5" EXACT [UniProtKB:P42830] xref: EMBL:AF349466 xref: EMBL:AJ315732 xref: EMBL:BC008376 xref: EMBL:L37036 xref: EMBL:U12709 xref: EMBL:X78686 xref: HGNC:HGNC:10642 xref: UniGene:Hs.89714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041666 ! CXCL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013520 name: CXCL6_human def: "C-X-C motif chemokine 6 precursor gene" [UniProtKB:P80162] synonym: "GCP2" EXACT [UniProtKB:P80162] synonym: "SCYB6" EXACT [UniProtKB:P80162] xref: EMBL:AC108029 xref: EMBL:BC013744 xref: EMBL:U81234 xref: EMBL:U83303 xref: EMBL:Y08770 xref: HGNC:HGNC:10643 xref: UniGene:Hs.164021 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041670 ! CXCL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013521 name: DSP_human def: "Desmoplakin gene" [UniProtKB:P15924] xref: EMBL:AF139065 xref: EMBL:AL031058 xref: EMBL:J05211 xref: EMBL:M77830 xref: HGNC:HGNC:3052 xref: UniGene:Hs.519873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042506 ! DESP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013525 name: EEF1A2_human def: "Elongation factor 1-alpha 2 gene" [UniProtKB:Q05639] synonym: "EEF1AL" EXACT [UniProtKB:Q05639] synonym: "STN" EXACT [UniProtKB:Q05639] xref: EMBL:AF163763 xref: EMBL:AL121829 xref: EMBL:BC000432 xref: EMBL:BC110409 xref: EMBL:L10340 xref: EMBL:X70940 xref: HGNC:HGNC:3192 xref: UniGene:Hs.433839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042870 ! EF1A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013526 name: ENOPH1_human def: "Enolase-phosphatase E1 gene" [UniProtKB:Q9UHY7] synonym: "MASA" EXACT [UniProtKB:Q9UHY7] synonym: "MSTP145" EXACT [UniProtKB:Q9UHY7] xref: EMBL:AF113125 xref: EMBL:AF177286 xref: EMBL:AK022656 xref: EMBL:BC001317 xref: EMBL:BC065815 xref: EMBL:CR457141 xref: HGNC:HGNC:24599 xref: UniGene:Hs.18442 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042028 ! ENOPH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013532 name: FCER1A_human def: "High affinity immunoglobulin epsilon receptor subunit alpha precursor gene" [UniProtKB:P12319] synonym: "FCE1A" EXACT [UniProtKB:P12319] xref: EMBL:A21606 xref: EMBL:BC005912 xref: EMBL:J03605 xref: EMBL:X06948 xref: HGNC:HGNC:3609 xref: UniGene:Hs.897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042830 ! FCERA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013535 name: FCGR1A_human def: "High affinity immunoglobulin gamma Fc receptor I precursor gene" [UniProtKB:P12314] synonym: "FCG1" EXACT [UniProtKB:P12314] synonym: "FCGR1" EXACT [UniProtKB:P12314] synonym: "IGFR1" EXACT [UniProtKB:P12314] xref: EMBL:L03418 xref: EMBL:M91550 xref: EMBL:M91551 xref: EMBL:M91552 xref: EMBL:M91553 xref: EMBL:M91554 xref: EMBL:M91555 xref: EMBL:X14355 xref: EMBL:X14356 xref: HGNC:HGNC:3613 xref: UniGene:Hs.77424 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042824 ! FCGR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013538 name: FLNA_human def: "Filamin-A gene" [UniProtKB:P21333] synonym: "FLN" EXACT [UniProtKB:P21333] synonym: "FLN1" EXACT [UniProtKB:P21333] xref: EMBL:AB191260 xref: EMBL:AB371574 xref: EMBL:AB371576 xref: EMBL:AK090427 xref: EMBL:L44140 xref: EMBL:X53416 xref: EMBL:X70082 xref: EMBL:X70085 xref: HGNC:HGNC:3754 xref: UniGene:Hs.195464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041401 ! FLNA_HUMAN relationship: codes_for CCO:B0041405 ! Q60FE5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013539 name: FLNB_human def: "Filamin-B gene" [UniProtKB:O75369] synonym: "FLN1L" EXACT [UniProtKB:O75369] synonym: "FLN3" EXACT [UniProtKB:O75369] synonym: "TABP" EXACT [UniProtKB:O75369] synonym: "TAP" EXACT [UniProtKB:O75369] xref: EMBL:AB209889 xref: EMBL:AF042166 xref: EMBL:AF043045 xref: EMBL:AF191594 xref: EMBL:AF191595 xref: EMBL:AF191596 xref: EMBL:AF191597 xref: EMBL:AF191598 xref: EMBL:AF191599 xref: EMBL:AF191600 xref: EMBL:AF191601 xref: EMBL:AF191602 xref: EMBL:AF191603 xref: EMBL:AF191604 xref: EMBL:AF191605 xref: EMBL:AF191606 xref: EMBL:AF191607 xref: EMBL:AF191608 xref: EMBL:AF191609 xref: EMBL:AF191610 xref: EMBL:AF191611 xref: EMBL:AF191612 xref: EMBL:AF191613 xref: EMBL:AF191614 xref: EMBL:AF191615 xref: EMBL:AF191616 xref: EMBL:AF191617 xref: EMBL:AF191618 xref: EMBL:AF191619 xref: EMBL:AF191620 xref: EMBL:AF191621 xref: EMBL:AF191622 xref: EMBL:AF191623 xref: EMBL:AF191624 xref: EMBL:AF191625 xref: EMBL:AF191626 xref: EMBL:AF191627 xref: EMBL:AF191628 xref: EMBL:AF191629 xref: EMBL:AF191630 xref: EMBL:AF191631 xref: EMBL:AF191632 xref: EMBL:AF191633 xref: EMBL:AF238609 xref: EMBL:AF353667 xref: EMBL:AL137574 xref: EMBL:BX641085 xref: EMBL:M62994 xref: HGNC:HGNC:3755 xref: UniGene:Hs.476448 xref: UniGene:Hs.666396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041417 ! FLNB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013540 name: FLNC_human def: "Filamin-C gene" [UniProtKB:Q14315] synonym: "ABPL" EXACT [UniProtKB:Q14315] synonym: "FLN2" EXACT [UniProtKB:Q14315] xref: EMBL:AF089841 xref: EMBL:AF146692 xref: EMBL:AF184119 xref: EMBL:AF184120 xref: EMBL:AF184121 xref: EMBL:AF184122 xref: EMBL:AF184123 xref: EMBL:AF184124 xref: EMBL:AF184125 xref: EMBL:AF184126 xref: EMBL:AF252549 xref: EMBL:AJ012737 xref: EMBL:AJ132990 xref: EMBL:X70083 xref: EMBL:X70084 xref: HGNC:HGNC:3756 xref: UniGene:Hs.58414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041399 ! FLNC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013542 name: GABBR2_human def: "Gamma-aminobutyric acid type B receptor subunit 2 precursor gene" [UniProtKB:O75899] synonym: "GPR51" EXACT [UniProtKB:O75899] synonym: "GPRC3B" EXACT [UniProtKB:O75899] xref: EMBL:AF056085 xref: EMBL:AF069755 xref: EMBL:AF074483 xref: EMBL:AF095784 xref: EMBL:AF099033 xref: EMBL:AJ012188 xref: EMBL:AL353782 xref: EMBL:AL356282 xref: EMBL:AL445495 xref: EMBL:AL591502 xref: EMBL:BC035071 xref: HGNC:HGNC:4507 xref: UniGene:Hs.198612 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041922 ! GABR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013546 name: GDF5_human def: "Growth/differentiation factor 5 precursor gene" [UniProtKB:P43026] synonym: "CDMP1" EXACT [UniProtKB:P43026] xref: EMBL:AL121586 xref: EMBL:BC032495 xref: EMBL:U13660 xref: EMBL:X80915 xref: HGNC:HGNC:4220 xref: UniGene:Hs.1573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042116 ! GDF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013548 name: GLIS2_human def: "Zinc finger protein GLIS2 gene" [UniProtKB:Q9BZE0] synonym: "NKL" EXACT [UniProtKB:Q9BZE0] xref: EMBL:AF325914 xref: HGNC:HGNC:29450 xref: UniGene:Hs.592087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020930 ! GLIS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013551 name: GRM1_human def: "Metabotropic glutamate receptor 1 precursor gene" [UniProtKB:Q13255] synonym: "GPRC1A" EXACT [UniProtKB:Q13255] synonym: "MGLUR1" EXACT [UniProtKB:Q13255] xref: EMBL:AL035698 xref: EMBL:AL096867 xref: EMBL:AL592423 xref: EMBL:L76627 xref: EMBL:L76631 xref: EMBL:U31215 xref: EMBL:U31216 xref: HGNC:HGNC:4593 xref: UniGene:Hs.32945 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042245 ! GRM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013552 name: GRM2_human def: "Metabotropic glutamate receptor 2 precursor gene" [UniProtKB:Q14416] synonym: "GPRC1B" EXACT [UniProtKB:Q14416] synonym: "MGLUR2" EXACT [UniProtKB:Q14416] xref: EMBL:AB045011 xref: EMBL:AY999299 xref: EMBL:BC113615 xref: EMBL:BC113619 xref: EMBL:L35318 xref: HGNC:HGNC:4594 xref: UniGene:Hs.121510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042239 ! GRM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013553 name: GRM3_human def: "Metabotropic glutamate receptor 3 precursor gene" [UniProtKB:Q14832] synonym: "GPRC1C" EXACT [UniProtKB:Q14832] synonym: "MGLUR3" EXACT [UniProtKB:Q14832] xref: EMBL:AC002081 xref: EMBL:AC005009 xref: EMBL:BC022496 xref: EMBL:BC041407 xref: EMBL:DQ315361 xref: EMBL:X77748 xref: HGNC:HGNC:4595 xref: UniGene:Hs.590575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042222 ! GRM3_HUMAN relationship: codes_for CCO:B0042247 ! Q2PNZ6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013554 name: GRM4_human def: "Metabotropic glutamate receptor 4 precursor gene" [UniProtKB:Q14833] synonym: "GPRC1D" EXACT [UniProtKB:Q14833] synonym: "MGLUR4" EXACT [UniProtKB:Q14833] xref: EMBL:AL590403 xref: EMBL:U92457 xref: EMBL:X80818 xref: HGNC:HGNC:4596 xref: UniGene:Hs.654847 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042225 ! GRM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013555 name: GRM5_human def: "Metabotropic glutamate receptor 5 precursor gene" [UniProtKB:P41594] synonym: "GPRC1E" EXACT [UniProtKB:P41594] synonym: "MGLUR5" EXACT [UniProtKB:P41594] xref: EMBL:AP003120 xref: EMBL:AY608336 xref: EMBL:D28538 xref: EMBL:D28539 xref: EMBL:S64316 xref: HGNC:HGNC:4597 xref: UniGene:Hs.147361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042221 ! A8MT20_HUMAN relationship: codes_for CCO:B0042230 ! GRM5_HUMAN relationship: codes_for CCO:B0042238 ! Q6J164_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013556 name: GRM6_human def: "Metabotropic glutamate receptor 6 precursor gene" [UniProtKB:O15303] synonym: "GPRC1F" EXACT [UniProtKB:O15303] synonym: "MGLUR6" EXACT [UniProtKB:O15303] xref: EMBL:U82083 xref: HGNC:HGNC:4598 xref: UniGene:Hs.248131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042244 ! GRM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013557 name: GRM7_human def: "Metabotropic glutamate receptor 7 precursor gene" [UniProtKB:Q14831] synonym: "GPRC1G" EXACT [UniProtKB:Q14831] synonym: "MGLUR7" EXACT [UniProtKB:Q14831] xref: EMBL:AF458052 xref: EMBL:AF458053 xref: EMBL:AF458054 xref: EMBL:U92458 xref: EMBL:X94552 xref: HGNC:HGNC:4599 xref: UniGene:Hs.606393 xref: UniGene:Hs.660131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042227 ! GRM7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013558 name: GRM8_human def: "Metabotropic glutamate receptor 8 precursor gene" [UniProtKB:O00222] synonym: "GPRC1H" EXACT [UniProtKB:O00222] synonym: "MGLUR8" EXACT [UniProtKB:O00222] xref: EMBL:AJ236921 xref: EMBL:AJ236922 xref: EMBL:AY608335 xref: EMBL:BC093725 xref: EMBL:BC101675 xref: EMBL:CH236947 xref: EMBL:U92459 xref: EMBL:U95025 xref: HGNC:HGNC:4600 xref: UniGene:Hs.449625 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042228 ! A4D0Y3_HUMAN relationship: codes_for CCO:B0042241 ! GRM8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013559 name: CXCL1_human def: "Growth-regulated alpha protein precursor gene" [UniProtKB:P09341] synonym: "GRO" EXACT [UniProtKB:P09341] synonym: "GRO1" EXACT [UniProtKB:P09341] synonym: "GROA" EXACT [UniProtKB:P09341] synonym: "MGSA" EXACT [UniProtKB:P09341] synonym: "SCYB1" EXACT [UniProtKB:P09341] xref: EMBL:BC011976 xref: EMBL:BT006880 xref: EMBL:J03561 xref: EMBL:X12510 xref: EMBL:X54489 xref: HGNC:HGNC:4602 xref: UniGene:Hs.789 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041668 ! GROA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013563 name: HIF3A_human def: "Hypoxia-inducible factor 3 alpha gene" [UniProtKB:Q9Y2N7] synonym: "MOP7" EXACT [UniProtKB:Q9Y2N7] xref: EMBL:AB054067 xref: EMBL:AB118749 xref: EMBL:AC007193 xref: EMBL:AF463492 xref: EMBL:AK021653 xref: EMBL:AK024095 xref: EMBL:AK027725 xref: EMBL:BC080551 xref: HGNC:HGNC:15825 xref: UniGene:Hs.420830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042408 ! HIF3A_HUMAN relationship: codes_for CCO:B0042416 ! A8MPQ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013564 name: EIF2S1_human def: "Eukaryotic translation initiation factor 2 subunit 1 gene" [UniProtKB:P05198] synonym: "EIF2A" EXACT [UniProtKB:P05198] xref: EMBL:BC002513 xref: EMBL:J02645 xref: HGNC:HGNC:3265 xref: UniGene:Hs.151777 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041436 ! IF2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013565 name: IL2RB_human def: "Interleukin-2 receptor subunit beta precursor gene" [UniProtKB:P14784] xref: EMBL:AF517934 xref: EMBL:AL022314 xref: EMBL:BC025691 xref: EMBL:CR456506 xref: EMBL:M26062 xref: HGNC:HGNC:6009 xref: UniGene:Hs.474787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042813 ! IL2RB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013566 name: IMPA1_human def: "Inositol monophosphatase gene" [UniProtKB:P29218] synonym: "IMPA" EXACT [UniProtKB:P29218] xref: EMBL:AF042729 xref: EMBL:AF178754 xref: EMBL:BC008381 xref: EMBL:BC009565 xref: EMBL:X66922 xref: EMBL:Y11360 xref: EMBL:Y11361 xref: EMBL:Y11362 xref: EMBL:Y11363 xref: EMBL:Y11364 xref: EMBL:Y11365 xref: EMBL:Y11366 xref: EMBL:Y11367 xref: HGNC:HGNC:6050 xref: UniGene:Hs.695965 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042291 ! IMPA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013567 name: IMPA2_human def: "Inositol monophosphatase 2 gene" [UniProtKB:O14732] synonym: "IMP.18P" EXACT [UniProtKB:O14732] xref: EMBL:AF014398 xref: EMBL:AF157096 xref: EMBL:AF157097 xref: EMBL:AF157098 xref: EMBL:AF157099 xref: EMBL:AF157100 xref: EMBL:AF157101 xref: EMBL:AF157102 xref: EMBL:AF200432 xref: EMBL:BC017176 xref: EMBL:BT007061 xref: HGNC:HGNC:6051 xref: UniGene:Hs.367992 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042283 ! IMPA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013584 name: LUC7L_human def: "Putative RNA-binding protein Luc7-like 1 gene" [UniProtKB:Q9NQ29] synonym: "LUC7L1" EXACT [UniProtKB:Q9NQ29] xref: EMBL:AE006462 xref: EMBL:AJ404326 xref: EMBL:AK001093 xref: EMBL:AY005111 xref: EMBL:BC003194 xref: EMBL:BC065198 xref: HGNC:HGNC:6723 xref: UniGene:Hs.16803 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025768 ! LUC7L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013585 name: MAP4K4_human def: "Mitogen-activated protein kinase kinase kinase kinase 4 gene" [UniProtKB:O95819] synonym: "HGK" EXACT [UniProtKB:O95819] synonym: "KIAA0687" EXACT [UniProtKB:O95819] synonym: "NIK" EXACT [UniProtKB:O95819] xref: EMBL:AB013385 xref: EMBL:AB014587 xref: EMBL:AF096300 xref: EMBL:AL137755 xref: EMBL:AY212247 xref: HGNC:HGNC:6866 xref: UniGene:Hs.431550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041953 ! M4K4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013587 name: MAFA_human def: "Transcription factor MafA gene" [UniProtKB:Q8NHW3] xref: EMBL:AB086960 xref: EMBL:AY083269 xref: HGNC:HGNC:23145 xref: UniGene:Hs.670866 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042185 ! MAFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013588 name: MAFF_human def: "Transcription factor MafF gene" [UniProtKB:Q9ULX9] xref: EMBL:AB025247 xref: EMBL:AJ010857 xref: EMBL:AK002001 xref: EMBL:AL021977 xref: EMBL:BC015037 xref: EMBL:BC067751 xref: HGNC:HGNC:6780 xref: UniGene:Hs.517617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042180 ! MAFF_HUMAN relationship: codes_for CCO:B0042181 ! B0QY71_HUMAN relationship: codes_for CCO:B0042182 ! B0QY70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013589 name: MAFG_human def: "Transcription factor MafG gene" [UniProtKB:O15525] xref: EMBL:AF059195 xref: EMBL:BC012327 xref: EMBL:U84249 xref: EMBL:Y11514 xref: HGNC:HGNC:6781 xref: UniGene:Hs.252229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042178 ! MAFG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013590 name: MAFK_human def: "V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (Avian) gene" [UniProtKB:A8WFP5] xref: EMBL:BC152387 xref: UniGene:Hs.520612 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042184 ! A8WFP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013591 name: MC3R_human def: "Melanocortin receptor 3 gene" [UniProtKB:P41968] xref: EMBL:AL139824 xref: EMBL:AY227893 xref: EMBL:BC069105 xref: EMBL:BC069599 xref: EMBL:BC096702 xref: EMBL:BC096737 xref: EMBL:BC098169 xref: EMBL:BC098351 xref: EMBL:L06155 xref: HGNC:HGNC:6931 xref: UniGene:Hs.248018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030552 ! MC3R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013592 name: MC4R_human def: "Melanocortin receptor 4 gene" [UniProtKB:P32245] xref: EMBL:AY236539 xref: EMBL:BC069172 xref: EMBL:BC101802 xref: EMBL:BC111992 xref: EMBL:L08603 xref: EMBL:S77415 xref: HGNC:HGNC:6932 xref: UniGene:Hs.532833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030574 ! MC4R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013593 name: MC5R_human def: "Melanocortin receptor 5 gene" [UniProtKB:P33032] xref: EMBL:AY268429 xref: EMBL:BC069153 xref: EMBL:BC069545 xref: EMBL:L27080 xref: EMBL:U08353 xref: EMBL:Z25470 xref: HGNC:HGNC:6933 xref: UniGene:Hs.248145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030569 ! MC5R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013595 name: MINK1_human def: "Misshapen-like kinase 1 gene" [UniProtKB:Q8N4C8] synonym: "MAP4K6" EXACT [UniProtKB:Q8N4C8] synonym: "MINK" EXACT [UniProtKB:Q8N4C8] xref: EMBL:AB035698 xref: EMBL:AB041926 xref: EMBL:BC034673 xref: HGNC:HGNC:17565 xref: UniGene:Hs.443417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041947 ! MINK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013599 name: MC1R_human def: "Melanocyte-stimulating hormone receptor gene" [UniProtKB:Q01726] synonym: "MSHR" EXACT [UniProtKB:Q01726] xref: EMBL:AF153431 xref: EMBL:AF153432 xref: EMBL:AF153433 xref: EMBL:AF153434 xref: EMBL:AF153435 xref: EMBL:AF153436 xref: EMBL:AF153437 xref: EMBL:AF263461 xref: EMBL:AF326275 xref: EMBL:AF514787 xref: EMBL:AY046528 xref: EMBL:AY046529 xref: EMBL:AY225228 xref: EMBL:BC007856 xref: EMBL:X65634 xref: EMBL:X67594 xref: HGNC:HGNC:6929 xref: UniGene:Hs.513829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030561 ! MSHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013602 name: NCOA4_human def: "Nuclear receptor coactivator 4 gene" [UniProtKB:Q13772] synonym: "ARA70" EXACT [UniProtKB:Q13772] synonym: "ELE1" EXACT [UniProtKB:Q13772] synonym: "RFG" EXACT [UniProtKB:Q13772] xref: EMBL:AL162047 xref: EMBL:BC001562 xref: EMBL:L49399 xref: EMBL:X71413 xref: EMBL:X77548 xref: HGNC:HGNC:7671 xref: UniGene:Hs.643658 xref: UniGene:Hs.705534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041593 ! NCOA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013603 name: NODAL_human def: "Nodal homolog precursor gene" [UniProtKB:Q96S42] xref: EMBL:AB067632 xref: EMBL:AC022532 xref: EMBL:BC033585 xref: EMBL:BC104976 xref: EMBL:BC112025 xref: HGNC:HGNC:7865 xref: UniGene:Hs.370414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042120 ! NODAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013604 name: NRK_human def: "Nik-related protein kinase gene" [UniProtKB:Q7Z2Y5] xref: EMBL:AK131549 xref: EMBL:BC108702 xref: EMBL:BX538345 xref: EMBL:Z68339 xref: EMBL:Z69734 xref: EMBL:Z70274 xref: EMBL:Z83850 xref: HGNC:HGNC:25391 xref: UniGene:Hs.209527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041948 ! NRK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013608 name: PDIA3_human def: "Protein disulfide-isomerase A3 precursor gene" [UniProtKB:P30101] synonym: "ERP57" EXACT [UniProtKB:P30101] synonym: "ERP60" EXACT [UniProtKB:P30101] synonym: "GRP58" EXACT [UniProtKB:P30101] xref: EMBL:BC014433 xref: EMBL:BC036000 xref: EMBL:BC071878 xref: EMBL:D16234 xref: EMBL:D83485 xref: EMBL:U42068 xref: EMBL:U75875 xref: EMBL:U75876 xref: EMBL:U75877 xref: EMBL:U75878 xref: EMBL:U75879 xref: EMBL:U75880 xref: EMBL:U75881 xref: EMBL:U75882 xref: EMBL:U75883 xref: EMBL:U75884 xref: EMBL:U75885 xref: EMBL:Z49835 xref: HGNC:HGNC:4606 xref: UniGene:Hs.591095 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0042031 ! PDIA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013616 name: PIK3CA_human def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform gene" [UniProtKB:P42336] xref: EMBL:BC113601 xref: EMBL:BC113603 xref: EMBL:U79143 xref: EMBL:Z29090 xref: HGNC:HGNC:8975 xref: UniGene:Hs.553498 xref: UniGene:Hs.699435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018350 ! PK3CA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013617 name: PIK3CD_human def: "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform gene" [UniProtKB:O00329] xref: EMBL:AL691449 xref: EMBL:BC132919 xref: EMBL:BC132921 xref: EMBL:DQ263594 xref: EMBL:U86453 xref: EMBL:Y10055 xref: HGNC:HGNC:8977 xref: UniGene:Hs.518451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018352 ! PK3CD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013619 name: PF4_human def: "Platelet factor 4 precursor gene" [UniProtKB:P02776] synonym: "CXCL4" EXACT [UniProtKB:P02776] synonym: "SCYB4" EXACT [UniProtKB:P02776] xref: EMBL:AC097709 xref: EMBL:AF349466 xref: EMBL:BC093965 xref: EMBL:BC112093 xref: EMBL:CR407677 xref: EMBL:M25897 xref: HGNC:HGNC:8861 xref: UniGene:Hs.81564 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041664 ! PLF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013625 name: ARHGAP12_human def: "Rho GTPase-activating protein 12 gene" [UniProtKB:Q8IWW6] xref: EMBL:AL137485 xref: EMBL:AL834250 xref: EMBL:AY033594 xref: EMBL:AY033595 xref: EMBL:BC051811 xref: EMBL:BC115362 xref: EMBL:BC115363 xref: HGNC:HGNC:16348 xref: UniGene:Hs.499264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041373 ! Q1RLN5_HUMAN relationship: codes_for CCO:B0041376 ! RHG12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013626 name: ARHGAP15_human def: "Rho GTPase-activating protein 15 gene" [UniProtKB:Q53QZ3] synonym: "BM024" EXACT [UniProtKB:Q53QZ3] synonym: "BM030" EXACT [UniProtKB:Q53QZ3] synonym: "BM046" EXACT [UniProtKB:Q53QZ3] xref: EMBL:AC013437 xref: EMBL:AC079584 xref: EMBL:AC079793 xref: EMBL:AC092652 xref: EMBL:AC096558 xref: EMBL:AC098857 xref: EMBL:AF212222 xref: EMBL:AF217507 xref: EMBL:AF217522 xref: EMBL:AY219338 xref: EMBL:BC016701 xref: EMBL:BC038976 xref: EMBL:CH471058 xref: HGNC:HGNC:21030 xref: UniGene:Hs.171011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041371 ! RHG15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013627 name: ARHGAP27_human def: "Rho GTPase-activating protein 27 gene" [UniProtKB:Q6ZUM4] synonym: "CAMGAP1" EXACT [UniProtKB:Q6ZUM4] synonym: "PP905" EXACT [UniProtKB:Q6ZUM4] xref: EMBL:AC003070 xref: EMBL:AC091132 xref: EMBL:AF258593 xref: EMBL:AK125535 xref: EMBL:AK290650 xref: EMBL:BC067345 xref: EMBL:BC101388 xref: EMBL:BC101389 xref: EMBL:BC101390 xref: EMBL:BC101391 xref: HGNC:HGNC:31813 xref: UniGene:Hs.205326 xref: UniGene:Hs.569809 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041368 ! RHG27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013630 name: RTN3_human def: "Reticulon-3 gene" [UniProtKB:O95197] synonym: "ASYIP" EXACT [UniProtKB:O95197] synonym: "NSPL2" EXACT [UniProtKB:O95197] xref: EMBL:AB209771 xref: EMBL:AF059524 xref: EMBL:AF059525 xref: EMBL:AF059526 xref: EMBL:AF059527 xref: EMBL:AF059528 xref: EMBL:AF059529 xref: EMBL:AF119297 xref: EMBL:AK222898 xref: EMBL:AY427821 xref: EMBL:AY750848 xref: EMBL:BC000634 xref: EMBL:BC010556 xref: EMBL:BC011394 xref: EMBL:BC022993 xref: EMBL:BC100822 xref: EMBL:BC100823 xref: EMBL:BC105981 xref: EMBL:BC105982 xref: EMBL:BC118550 xref: EMBL:BC118628 xref: EMBL:BK001681 xref: EMBL:BK001684 xref: EMBL:BK001685 xref: HGNC:HGNC:10469 xref: UniGene:Hs.473761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041728 ! RTN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013631 name: RTN4_human def: "Reticulon-4 gene" [UniProtKB:Q9NQC3] synonym: "KIAA0886" EXACT [UniProtKB:Q9NQC3] synonym: "My043" EXACT [UniProtKB:Q9NQC3] synonym: "NOGO" EXACT [UniProtKB:Q9NQC3] synonym: "SP1507" EXACT [UniProtKB:Q9NQC3] xref: EMBL:AB015639 xref: EMBL:AB020693 xref: EMBL:AB040462 xref: EMBL:AB040463 xref: EMBL:AF063601 xref: EMBL:AF077050 xref: EMBL:AF087901 xref: EMBL:AF125103 xref: EMBL:AF132047 xref: EMBL:AF132048 xref: EMBL:AF148537 xref: EMBL:AF148538 xref: EMBL:AF177332 xref: EMBL:AF320999 xref: EMBL:AF333336 xref: EMBL:AJ251383 xref: EMBL:AJ251384 xref: EMBL:AJ251385 xref: EMBL:AY102279 xref: EMBL:AY102285 xref: EMBL:BC001035 xref: EMBL:BC007109 xref: EMBL:BC010737 xref: EMBL:BC012619 xref: EMBL:BC014366 xref: EMBL:BC026788 xref: EMBL:BC068991 xref: EMBL:BC150182 xref: EMBL:BC152425 xref: EMBL:BC152555 xref: EMBL:CH471053 xref: HGNC:HGNC:14085 xref: UniGene:Hs.645283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041735 ! RTN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013634 name: SLC9A2_human def: "Sodium/hydrogen exchanger 2 gene" [UniProtKB:Q9UBY0] synonym: "NHE2" EXACT [UniProtKB:Q9UBY0] xref: EMBL:AC007239 xref: EMBL:AF073299 xref: HGNC:HGNC:11072 xref: UniGene:Hs.250083 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020193 ! SL9A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013638 name: STARD8_human def: "StAR-related lipid transfer protein 8 gene" [UniProtKB:Q92502] synonym: "DLC3" EXACT [UniProtKB:Q92502] synonym: "KIAA0189" EXACT [UniProtKB:Q92502] xref: EMBL:AK291747 xref: EMBL:AL360076 xref: EMBL:BC035587 xref: EMBL:CH471132 xref: EMBL:CR749411 xref: EMBL:D80011 xref: HGNC:HGNC:19161 xref: UniGene:Hs.95140 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041421 ! STAR8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013647 name: WISP1_human def: "WNT1-inducible-signaling pathway protein 1 precursor gene" [UniProtKB:O95388] synonym: "CCN4" EXACT [UniProtKB:O95388] xref: EMBL:AB034725 xref: EMBL:AF100779 xref: EMBL:AF192304 xref: EMBL:AY196488 xref: EMBL:BC074840 xref: EMBL:BC074841 xref: HGNC:HGNC:12769 xref: UniGene:Hs.492974 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021692 ! WISP1_HUMAN relationship: codes_for CCO:B0056450 ! Q5JBS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013651 name: HLA-DRA_human def: "HLA class II histocompatibility antigen, DR alpha chain precursor gene" [UniProtKB:P01903] synonym: "HLA-DRA1" EXACT [UniProtKB:P01903] xref: EMBL:AF481359 xref: EMBL:AL662796 xref: EMBL:AL670296 xref: EMBL:AL935032 xref: EMBL:BC032350 xref: EMBL:BC071659 xref: EMBL:BX120007 xref: EMBL:CH471081 xref: EMBL:CR457013 xref: EMBL:J00194 xref: EMBL:J00201 xref: EMBL:J00203 xref: EMBL:J00204 xref: EMBL:K01171 xref: EMBL:M60334 xref: EMBL:V00523 xref: EMBL:X00274 xref: EMBL:Z84814 xref: HGNC:HGNC:4947 xref: UniGene:Hs.520048 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063340 ! 2DRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013659 name: CHRND_human def: "Acetylcholine receptor subunit delta precursor gene" [UniProtKB:Q07001] synonym: "ACHRD" EXACT [UniProtKB:Q07001] xref: EMBL:AC092165 xref: EMBL:BC093923 xref: EMBL:BC093925 xref: EMBL:X55019 xref: HGNC:HGNC:1965 xref: UniGene:Hs.156289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055779 ! ACHD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013661 name: CAPN10_human def: "Calpain-10 gene" [UniProtKB:Q9HC96] synonym: "KIAA1845" EXACT [UniProtKB:Q9HC96] xref: EMBL:AB058748 xref: EMBL:AC124862 xref: EMBL:AF089088 xref: EMBL:AF089090 xref: EMBL:AF089091 xref: EMBL:AF089092 xref: EMBL:AF089093 xref: EMBL:AF089094 xref: EMBL:AF089095 xref: EMBL:AF089096 xref: EMBL:AK074807 xref: EMBL:BC004260 xref: EMBL:BC007553 xref: HGNC:HGNC:1477 xref: UniGene:Hs.112218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058800 ! CAN10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013665 name: MICB_human def: "MHC class I polypeptide-related sequence B precursor gene" [UniProtKB:Q29980] synonym: "PERB11.2" EXACT [UniProtKB:Q29980] xref: EMBL:AB003609 xref: EMBL:AB003610 xref: EMBL:AB003611 xref: EMBL:AB003612 xref: EMBL:AB003613 xref: EMBL:AB003614 xref: EMBL:AB003615 xref: EMBL:AB003616 xref: EMBL:AB003617 xref: EMBL:AF021221 xref: EMBL:AF021222 xref: EMBL:AF021223 xref: EMBL:AF021224 xref: EMBL:AF021225 xref: EMBL:AF021226 xref: EMBL:AJ251156 xref: EMBL:AJ251157 xref: EMBL:AJ251158 xref: EMBL:AJ251159 xref: EMBL:AJ251160 xref: EMBL:AJ251161 xref: EMBL:AJ563706 xref: EMBL:AJ606906 xref: EMBL:AJ606907 xref: EMBL:AJ606908 xref: EMBL:AJ606909 xref: EMBL:AJ606910 xref: EMBL:AJ606911 xref: EMBL:AJ606912 xref: EMBL:AJ606913 xref: EMBL:AJ606914 xref: EMBL:AJ606915 xref: EMBL:AJ606916 xref: EMBL:AJ606917 xref: EMBL:AJ606918 xref: EMBL:AJ606919 xref: EMBL:AJ606920 xref: EMBL:AJ606921 xref: EMBL:AJ606922 xref: EMBL:AJ606923 xref: EMBL:AJ606929 xref: EMBL:AJ606930 xref: EMBL:AJ606931 xref: EMBL:AL662866 xref: EMBL:AL663061 xref: EMBL:AY885251 xref: EMBL:BA000025 xref: EMBL:BX001040 xref: EMBL:BX005439 xref: EMBL:CR753820 xref: EMBL:CR753864 xref: EMBL:CR788288 xref: EMBL:EF051579 xref: EMBL:EF051580 xref: EMBL:U65416 xref: EMBL:U69978 xref: EMBL:U95729 xref: EMBL:U95730 xref: EMBL:U95731 xref: EMBL:U95732 xref: EMBL:U95733 xref: EMBL:U95734 xref: EMBL:X91625 xref: HGNC:HGNC:7091 xref: UniGene:Hs.211580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056199 ! MICB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013689 name: RBM14_human def: "RNA-binding protein 14 gene" [UniProtKB:Q96PK6] synonym: "SIP" EXACT [UniProtKB:Q96PK6] xref: EMBL:AF080561 xref: EMBL:AF315632 xref: EMBL:AF315633 xref: EMBL:AK222830 xref: EMBL:BC000488 xref: EMBL:CR749306 xref: HGNC:HGNC:14219 xref: UniGene:Hs.705604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058337 ! RBM14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013699 name: DKFZp686I225_human def: "Putative uncharacterized protein DKFZp686I225 gene" [UniProtKB:Q5CZH9] xref: EMBL:BX648574 xref: HGNC:HGNC:494 xref: UniGene:Hs.499725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041531 ! Q5CZH9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013720 name: DKFZp686P17114_human def: "Putative uncharacterized protein DKFZp686P17114 gene" [UniProtKB:Q7Z3G4] xref: EMBL:BX537917 xref: HGNC:HGNC:494 xref: UniGene:Hs.499725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041528 ! Q7Z3G4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013721 name: DKFZp686H0688_human def: "Putative uncharacterized protein DKFZp686H0688 gene" [UniProtKB:Q7Z3L5] xref: EMBL:BX537758 xref: HGNC:HGNC:493 xref: UniGene:Hs.620557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041521 ! Q7Z3L5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0013732 name: CHRNB1_human def: "Acetylcholine receptor subunit beta precursor gene" [UniProtKB:P11230] synonym: "ACHRB" EXACT [UniProtKB:P11230] synonym: "CHRNB" EXACT [UniProtKB:P11230] xref: EMBL:BC011371 xref: EMBL:X14830 xref: HGNC:HGNC:1961 xref: UniGene:Hs.330386 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054987 ! ACHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014149 name: BBS2_human def: "Bardet-Biedl syndrome 2 protein gene" [UniProtKB:Q9BXC9] xref: EMBL:AF342736 xref: EMBL:AK027635 xref: EMBL:BC014140 xref: HGNC:HGNC:967 xref: UniGene:Hs.333738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043419 ! BBS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014150 name: C1orf216_human def: "UPF0500 protein C1orf216 gene" [UniProtKB:Q8TAB5] xref: EMBL:AK096303 xref: EMBL:AK096466 xref: EMBL:BC026909 xref: EMBL:CH471059 xref: HGNC:HGNC:26800 xref: UniGene:Hs.112023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043422 ! CA216_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014151 name: CBWD3_human def: "COBW domain-containing protein 3 gene" [UniProtKB:Q5JTY5] xref: EMBL:AL353608 xref: HGNC:HGNC:18519 xref: UniGene:Hs.597638 xref: UniGene:Hs.645337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043444 ! CBWD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014152 name: CENTA1_human def: "Centaurin-alpha-1 gene" [UniProtKB:O75689] xref: EMBL:AB097049 xref: EMBL:AF082324 xref: EMBL:AJ006422 xref: EMBL:BC033747 xref: EMBL:CH236965 xref: EMBL:CH471144 xref: HGNC:HGNC:16486 xref: UniGene:Hs.644629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043443 ! CENA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014153 name: CLUAP1_human def: "Clusterin-associated protein 1 gene" [UniProtKB:Q96AJ1] synonym: "KIAA0643" EXACT [UniProtKB:Q96AJ1] xref: EMBL:AB014543 xref: EMBL:AB089691 xref: EMBL:AK023319 xref: EMBL:AK023359 xref: EMBL:BC017070 xref: HGNC:HGNC:19009 xref: UniGene:Hs.155995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043416 ! CLUA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014154 name: DDX19B_human def: "ATP-dependent RNA helicase DDX19B gene" [UniProtKB:Q9UMR2] synonym: "DBP5" EXACT [UniProtKB:Q9UMR2] synonym: "DDX19" EXACT [UniProtKB:Q9UMR2] xref: EMBL:AJ237946 xref: EMBL:AL136639 xref: EMBL:BC003626 xref: EMBL:CH471241 xref: EMBL:CR457215 xref: EMBL:CR533509 xref: HGNC:HGNC:2742 xref: UniGene:Hs.221761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043447 ! DD19B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014155 name: EZH2_human def: "Polycomb protein EZH2 gene" [UniProtKB:Q15910] synonym: "KMT6" EXACT [UniProtKB:Q15910] xref: EMBL:AC006323 xref: EMBL:AC073140 xref: EMBL:U52965 xref: EMBL:U61145 xref: EMBL:X95653 xref: HGNC:HGNC:3527 xref: UniGene:Hs.444082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043441 ! EZH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014156 name: FBXO34_human def: "F-box only protein 34 gene" [UniProtKB:Q9NWN3] synonym: "FBX34" EXACT [UniProtKB:Q9NWN3] xref: EMBL:AK000732 xref: EMBL:BC109120 xref: EMBL:BC109121 xref: EMBL:BX248268 xref: EMBL:CR457249 xref: HGNC:HGNC:20201 xref: UniGene:Hs.525348 xref: UniGene:Hs.654725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043442 ! FBX34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014157 name: FBXO41_human def: "F-box only protein 41 gene" [UniProtKB:Q8TF61] synonym: "FBX41" EXACT [UniProtKB:Q8TF61] synonym: "KIAA1940" EXACT [UniProtKB:Q8TF61] xref: EMBL:AB075820 xref: EMBL:AC010913 xref: HGNC:HGNC:29409 xref: UniGene:Hs.23158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043435 ! FBX41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014158 name: FBXL7_human def: "F-box/LRR-repeat protein 7 gene" [UniProtKB:Q9UJT9] synonym: "FBL6" EXACT [UniProtKB:Q9UJT9] synonym: "FBL7" EXACT [UniProtKB:Q9UJT9] synonym: "KIAA0840" EXACT [UniProtKB:Q9UJT9] xref: EMBL:AB020647 xref: EMBL:AF174593 xref: EMBL:AF199356 xref: EMBL:BC075061 xref: HGNC:HGNC:13604 xref: UniGene:Hs.433057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043431 ! FBXL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014159 name: FBXW2_human def: "F-box/WD repeat-containing protein 2 gene" [UniProtKB:Q9UKT8] synonym: "FBW2" EXACT [UniProtKB:Q9UKT8] synonym: "FWD2" EXACT [UniProtKB:Q9UKT8] xref: EMBL:AF129531 xref: EMBL:AF145024 xref: EMBL:AF176698 xref: EMBL:AF193594 xref: EMBL:AK022484 xref: EMBL:AL161911 xref: EMBL:BC018738 xref: EMBL:BC110334 xref: HGNC:HGNC:13608 xref: UniGene:Hs.494985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043432 ! FBXW2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014160 name: FBXW5_human def: "F-box/WD repeat-containing protein 5 gene" [UniProtKB:Q969U6] synonym: "FBW5" EXACT [UniProtKB:Q969U6] synonym: "PP3971" EXACT [UniProtKB:Q969U6] xref: EMBL:AF217998 xref: EMBL:AF258569 xref: EMBL:AK026081 xref: EMBL:AL137631 xref: EMBL:AL807752 xref: EMBL:BC000850 xref: EMBL:BC004541 xref: EMBL:BC009429 xref: EMBL:BC014130 xref: EMBL:BC014297 xref: HGNC:HGNC:13613 xref: UniGene:Hs.522507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043433 ! FBXW5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014161 name: FBXW8_human def: "F-box/WD repeat-containing protein 8 gene" [UniProtKB:Q8N3Y1] synonym: "FBW6" EXACT [UniProtKB:Q8N3Y1] synonym: "FBW8" EXACT [UniProtKB:Q8N3Y1] synonym: "FBX29" EXACT [UniProtKB:Q8N3Y1] synonym: "FBXO29" EXACT [UniProtKB:Q8N3Y1] synonym: "FBXW6" EXACT [UniProtKB:Q8N3Y1] xref: EMBL:AF176707 xref: EMBL:BC037296 xref: HGNC:HGNC:13597 xref: UniGene:Hs.624537 xref: UniGene:Hs.696428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043434 ! FBXW8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014162 name: HEXA_human def: "Beta-hexosaminidase subunit alpha precursor gene" [UniProtKB:P06865] xref: EMBL:BC018927 xref: EMBL:BC084537 xref: EMBL:M13520 xref: EMBL:M16411 xref: EMBL:M16412 xref: EMBL:M16413 xref: EMBL:M16414 xref: EMBL:M16415 xref: EMBL:M16416 xref: EMBL:M16417 xref: EMBL:M16418 xref: EMBL:M16419 xref: EMBL:M16420 xref: EMBL:M16421 xref: EMBL:M16422 xref: EMBL:M16423 xref: EMBL:M16424 xref: EMBL:S62047 xref: EMBL:S62049 xref: EMBL:S62051 xref: EMBL:S62053 xref: EMBL:S62055 xref: EMBL:S62057 xref: EMBL:S62059 xref: EMBL:S62061 xref: EMBL:S62063 xref: EMBL:S62066 xref: EMBL:S62068 xref: EMBL:S62070 xref: EMBL:S62072 xref: EMBL:S62076 xref: HGNC:HGNC:4878 xref: UniGene:Hs.604479 xref: UniGene:Hs.655912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043445 ! HEXA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014163 name: ITPKB_human def: "Inositol-trisphosphate 3-kinase B gene" [UniProtKB:P27987] xref: EMBL:AJ242780 xref: EMBL:AL365444 xref: EMBL:BC015009 xref: EMBL:X57206 xref: EMBL:Y18024 xref: HGNC:HGNC:6179 xref: UniGene:Hs.528087 xref: UniGene:Hs.659396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043425 ! IP3KB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014164 name: KCTD17_human def: "BTB/POZ domain-containing protein KCTD17 gene" [UniProtKB:Q8N5Z5] xref: EMBL:AK022304 xref: EMBL:AL022314 xref: EMBL:BC025403 xref: EMBL:BC031038 xref: EMBL:CH471095 xref: HGNC:HGNC:25705 xref: UniGene:Hs.517597 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043424 ! KCD17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014165 name: NCOA3_human def: "Nuclear receptor coactivator 3 gene" [UniProtKB:Q9Y6Q9] synonym: "AIB1" EXACT [UniProtKB:Q9Y6Q9] synonym: "RAC3" EXACT [UniProtKB:Q9Y6Q9] synonym: "TRAM1" EXACT [UniProtKB:Q9Y6Q9] xref: EMBL:AF010227 xref: EMBL:AF012108 xref: EMBL:AF016031 xref: EMBL:AF036892 xref: EMBL:AL034418 xref: HGNC:HGNC:7670 xref: UniGene:Hs.592142 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043428 ! NCOA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014166 name: PRNP_human def: "Major prion protein precursor gene" [UniProtKB:P04156] synonym: "PRIP" EXACT [UniProtKB:P04156] synonym: "PRP" EXACT [UniProtKB:P04156] xref: EMBL:AF030575 xref: EMBL:AF076976 xref: EMBL:AL133396 xref: EMBL:AY008282 xref: EMBL:BC012844 xref: EMBL:BC022532 xref: EMBL:D00015 xref: EMBL:DQ408531 xref: EMBL:M13667 xref: EMBL:M13899 xref: EMBL:M81929 xref: EMBL:M81930 xref: EMBL:S71208 xref: EMBL:S71210 xref: EMBL:S71212 xref: EMBL:S80732 xref: EMBL:S80743 xref: EMBL:U29185 xref: EMBL:X83416 xref: HGNC:HGNC:9449 xref: UniGene:Hs.472010 xref: UniGene:Hs.610285 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043436 ! PRIO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014167 name: PSME2_human def: "Proteasome activator complex subunit 2 gene" [UniProtKB:Q9UL46] xref: EMBL:AF079558 xref: EMBL:BC004368 xref: EMBL:BC019885 xref: EMBL:BC072025 xref: EMBL:D45248 xref: HGNC:HGNC:9569 xref: UniGene:Hs.434081 xref: UniGene:Hs.512410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043427 ! PSME2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014168 name: RASSF8_human def: "Ras association domain-containing protein 8 gene" [UniProtKB:Q8NHQ8] synonym: "C12orf2" EXACT [UniProtKB:Q8NHQ8] xref: EMBL:AB093206 xref: EMBL:AY665468 xref: EMBL:BC030021 xref: EMBL:U82396 xref: HGNC:HGNC:13232 xref: UniGene:Hs.696433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043423 ! RASF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014169 name: RBM15B_human def: "Putative RNA-binding protein 15B gene" [UniProtKB:Q8NDT2] xref: EMBL:AL831838 xref: EMBL:AY545557 xref: EMBL:BC001367 xref: HGNC:HGNC:24303 xref: UniGene:Hs.118738 xref: UniGene:Hs.476291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043450 ! RB15B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014170 name: RERE_human def: "Arginine-glutamic acid dipeptide repeats protein gene" [UniProtKB:Q9P2R6] synonym: "ARG" EXACT [UniProtKB:Q9P2R6] synonym: "ARP" EXACT [UniProtKB:Q9P2R6] synonym: "ATN1L" EXACT [UniProtKB:Q9P2R6] synonym: "KIAA0458" EXACT [UniProtKB:Q9P2R6] xref: EMBL:AB007927 xref: EMBL:AB036737 xref: EMBL:AF016005 xref: EMBL:AF041096 xref: EMBL:AF041097 xref: EMBL:AF041098 xref: EMBL:AF041099 xref: EMBL:AF041100 xref: EMBL:AF041101 xref: EMBL:AF041102 xref: EMBL:AF041103 xref: EMBL:AF041104 xref: EMBL:AF118275 xref: EMBL:AL096855 xref: EMBL:AL356072 xref: EMBL:AL357713 xref: EMBL:CH471130 xref: HGNC:HGNC:9965 xref: UniGene:Hs.463041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043437 ! RERE_HUMAN relationship: codes_for CCO:B0054227 ! B1AKN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014171 name: MRPL10_human def: "39S ribosomal protein L10, mitochondrial precursor gene" [UniProtKB:Q7Z7H8] synonym: "MRPL8" EXACT [UniProtKB:Q7Z7H8] synonym: "RPML8" EXACT [UniProtKB:Q7Z7H8] xref: EMBL:AB051618 xref: EMBL:AC003665 xref: EMBL:BC015904 xref: EMBL:BC052601 xref: HGNC:HGNC:14055 xref: UniGene:Hs.347535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043446 ! RM10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014172 name: RNF126_human def: "RING finger protein 126 gene" [UniProtKB:Q9BV68] xref: EMBL:AK000559 xref: EMBL:BC001442 xref: EMBL:BC025374 xref: HGNC:HGNC:21151 xref: UniGene:Hs.69554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043418 ! RN126_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014173 name: RNF5_human def: "E3 ubiquitin-protein ligase RNF5 gene" [UniProtKB:Q99942] synonym: "G16" EXACT [UniProtKB:Q99942] synonym: "NG2" EXACT [UniProtKB:Q99942] synonym: "RMA1" EXACT [UniProtKB:Q99942] xref: EMBL:AB056869 xref: EMBL:AJ243936 xref: EMBL:AL662830 xref: EMBL:AL662884 xref: EMBL:AL845464 xref: EMBL:BC004155 xref: EMBL:BC111392 xref: EMBL:BC119741 xref: EMBL:BC119742 xref: EMBL:BC127651 xref: EMBL:BC127652 xref: EMBL:BC148255 xref: EMBL:BT007105 xref: EMBL:BX284686 xref: EMBL:BX927239 xref: EMBL:CR812478 xref: EMBL:CR933878 xref: EMBL:U89336 xref: HGNC:HGNC:10068 xref: UniGene:Hs.534342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043430 ! RNF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014174 name: SNRPB_human def: "Small nuclear ribonucleoprotein-associated proteins B and B' gene" [UniProtKB:P14678] synonym: "COD" EXACT [UniProtKB:P14678] synonym: "SNRPB1" EXACT [UniProtKB:P14678] xref: EMBL:AF134822 xref: EMBL:AF134823 xref: EMBL:AF134824 xref: EMBL:AF134825 xref: EMBL:AL049650 xref: EMBL:M34081 xref: EMBL:M34082 xref: EMBL:X15893 xref: EMBL:X17567 xref: EMBL:X17568 xref: EMBL:X52979 xref: HGNC:HGNC:11153 xref: UniGene:Hs.83753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043440 ! RSMB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014175 name: MRPS9_human def: "28S ribosomal protein S9, mitochondrial precursor gene" [UniProtKB:P82933] synonym: "RPMS9" EXACT [UniProtKB:P82933] xref: EMBL:BF034318 xref: HGNC:HGNC:14501 xref: UniGene:Hs.590900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043448 ! RT09_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014176 name: SNRPF_human def: "Small nuclear ribonucleoprotein F gene" [UniProtKB:P62306] synonym: "PBSCF" EXACT [UniProtKB:P62306] xref: EMBL:BC002505 xref: EMBL:BC063397 xref: EMBL:BC128452 xref: EMBL:BC128453 xref: EMBL:CR456751 xref: EMBL:X85372 xref: HGNC:HGNC:11162 xref: UniGene:Hs.105465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043438 ! RUXF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014177 name: SERF2_human def: "Small EDRK-rich factor 2 gene" [UniProtKB:P84101] synonym: "FAM2C" EXACT [UniProtKB:P84101] xref: EMBL:AF073298 xref: EMBL:AF320073 xref: EMBL:BC009869 xref: EMBL:BC015491 xref: HGNC:HGNC:10757 xref: UniGene:Hs.424126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043420 ! SERF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014178 name: TNNT1_human def: "Troponin T, slow skeletal muscle gene" [UniProtKB:P13805] synonym: "TNT" EXACT [UniProtKB:P13805] xref: EMBL:AJ011712 xref: EMBL:AJ011713 xref: EMBL:BC010963 xref: EMBL:BC022086 xref: EMBL:BC034143 xref: EMBL:M19308 xref: EMBL:M19309 xref: EMBL:S66057 xref: EMBL:S66170 xref: EMBL:S69208 xref: EMBL:S69209 xref: HGNC:HGNC:11948 xref: UniGene:Hs.631558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043421 ! TNNT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014179 name: TRIM39_human def: "Tripartite motif-containing protein 39 gene" [UniProtKB:Q9HCM9] synonym: "RNF23" EXACT [UniProtKB:Q9HCM9] synonym: "TFP" EXACT [UniProtKB:Q9HCM9] xref: EMBL:AB046381 xref: EMBL:AB110937 xref: EMBL:BC007661 xref: EMBL:BC034985 xref: EMBL:BT007370 xref: HGNC:HGNC:10065 xref: UniGene:Hs.413493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043417 ! TRI39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014180 name: TRIM9_human def: "Tripartite motif-containing protein 9 gene" [UniProtKB:Q9C026] synonym: "KIAA0282" EXACT [UniProtKB:Q9C026] synonym: "RNF91" EXACT [UniProtKB:Q9C026] xref: EMBL:AF220036 xref: EMBL:AF220037 xref: EMBL:AF220038 xref: EMBL:AK055388 xref: EMBL:BC013414 xref: EMBL:BC063872 xref: EMBL:D87458 xref: HGNC:HGNC:16288 xref: UniGene:Hs.654750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043426 ! TRIM9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014181 name: VCL_human def: "Vinculin gene" [UniProtKB:P18206] xref: EMBL:AL596247 xref: EMBL:AL731576 xref: EMBL:BC039174 xref: EMBL:BX537994 xref: EMBL:L04933 xref: EMBL:M33308 xref: EMBL:S87175 xref: EMBL:S87178 xref: EMBL:S87180 xref: EMBL:S87218 xref: EMBL:S87223 xref: HGNC:HGNC:12665 xref: UniGene:Hs.699180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043439 ! VINC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014182 name: XRN2_human def: "5'-3' exoribonuclease 2 gene" [UniProtKB:Q9H0D6] xref: EMBL:AF064257 xref: EMBL:AF152169 xref: EMBL:AK000084 xref: EMBL:AL117332 xref: EMBL:AL136841 xref: EMBL:AL158013 xref: EMBL:AY382900 xref: EMBL:BC006417 xref: HGNC:HGNC:12836 xref: UniGene:Hs.255932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043429 ! XRN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014183 name: FLJ10324_human def: "Putative uncharacterized protein FLJ10324 gene" [UniProtKB:Q75LH2] xref: EMBL:AC092610 xref: UniGene:Hs.667336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043449 ! Q75LH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014220 name: GJA1_human def: "Gap junction alpha-1 protein gene" [UniProtKB:P17302] synonym: "GJAL" EXACT [UniProtKB:P17302] xref: EMBL:AF151980 xref: EMBL:AL139098 xref: EMBL:BC026329 xref: EMBL:CH471051 xref: EMBL:CR541660 xref: EMBL:M65188 xref: EMBL:X52947 xref: HGNC:HGNC:4274 xref: UniGene:Hs.74471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043520 ! CXA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014229 name: DEDD2_human def: "DNA-binding death effector domain-containing protein 2 gene" [UniProtKB:Q8WXF8] synonym: "FLAME3" EXACT [UniProtKB:Q8WXF8] synonym: "PSEC0004" EXACT [UniProtKB:Q8WXF8] xref: EMBL:AF443591 xref: EMBL:AF457575 xref: EMBL:AK075328 xref: EMBL:AY125488 xref: EMBL:BC013372 xref: EMBL:BC027930 xref: HGNC:HGNC:24450 xref: UniGene:Hs.515432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043605 ! DEDD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014230 name: DEDD_human def: "Death effector domain-containing protein gene" [UniProtKB:O75618] synonym: "DEDPRO1" EXACT [UniProtKB:O75618] synonym: "DEFT" EXACT [UniProtKB:O75618] synonym: "KE05" EXACT [UniProtKB:O75618] xref: EMBL:AF043733 xref: EMBL:AF064605 xref: EMBL:AF083236 xref: EMBL:AF100341 xref: EMBL:AJ010973 xref: EMBL:AL591806 xref: EMBL:BC013910 xref: EMBL:BC016724 xref: EMBL:CH471121 xref: EMBL:CR536556 xref: HGNC:HGNC:2755 xref: UniGene:Hs.517342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043604 ! DEDD_HUMAN relationship: codes_for CCO:B0043606 ! B1AQP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014231 name: POLG_human def: "DNA polymerase subunit gamma-1 gene" [UniProtKB:P54098] synonym: "MDP1" EXACT [UniProtKB:P54098] synonym: "POLG1" EXACT [UniProtKB:P54098] synonym: "POLGA" EXACT [UniProtKB:P54098] xref: EMBL:AF497906 xref: EMBL:BC042571 xref: EMBL:BC050559 xref: EMBL:D84103 xref: EMBL:U60325 xref: EMBL:X98093 xref: HGNC:HGNC:9179 xref: UniGene:Hs.702153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017165 ! DPOG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014234 name: FBP1_human def: "Fructose-1,6-bisphosphatase 1 gene" [UniProtKB:P09467] synonym: "FBP" EXACT [UniProtKB:P09467] xref: EMBL:AF073475 xref: EMBL:AK223395 xref: EMBL:AL161728 xref: EMBL:AY866483 xref: EMBL:BC012927 xref: EMBL:D26054 xref: EMBL:D26055 xref: EMBL:D26056 xref: EMBL:L10320 xref: EMBL:M19922 xref: EMBL:U21925 xref: EMBL:U21926 xref: EMBL:U21927 xref: EMBL:U21929 xref: EMBL:U21930 xref: EMBL:U21931 xref: EMBL:U47918 xref: EMBL:U47919 xref: HGNC:HGNC:3606 xref: UniGene:Hs.494496 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043610 ! F16P1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014235 name: FBP2_human def: "Fructose-1,6-bisphosphatase isozyme 2 gene" [UniProtKB:O00757] xref: EMBL:AL161728 xref: EMBL:BC113632 xref: EMBL:BC117477 xref: EMBL:CR536483 xref: EMBL:Y10812 xref: HGNC:HGNC:3607 xref: UniGene:Hs.61255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043612 ! F16P2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014237 name: FBXL10_human def: "JmjC domain-containing histone demethylation protein 1B gene" [UniProtKB:Q8NHM5] synonym: "CXXC2" EXACT [UniProtKB:Q8NHM5] synonym: "FBL10" EXACT [UniProtKB:Q8NHM5] synonym: "JHDM1B" EXACT [UniProtKB:Q8NHM5] synonym: "PCCX2" EXACT [UniProtKB:Q8NHM5] xref: EMBL:AB031230 xref: EMBL:AJ459424 xref: EMBL:AK027440 xref: EMBL:AK027692 xref: EMBL:AK074718 xref: EMBL:AL133572 xref: EMBL:BC008735 xref: HGNC:HGNC:13610 xref: UniGene:Hs.524800 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043543 ! JHD1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014238 name: LRRC41_human def: "Leucine-rich repeat-containing protein 41 gene" [UniProtKB:Q15345] synonym: "MUF1" EXACT [UniProtKB:Q15345] synonym: "PP7759" EXACT [UniProtKB:Q15345] xref: EMBL:AF370430 xref: EMBL:AK125827 xref: EMBL:AL121602 xref: EMBL:AL122001 xref: EMBL:BC004953 xref: EMBL:BC101522 xref: EMBL:BC101524 xref: EMBL:BX537366 xref: EMBL:X86018 xref: HGNC:HGNC:16917 xref: UniGene:Hs.144941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043602 ! LRC41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014239 name: PIP5K1A_human def: "Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha gene" [UniProtKB:Q99755] xref: EMBL:AL592424 xref: EMBL:BC007833 xref: EMBL:U78575 xref: EMBL:U78576 xref: EMBL:U78577 xref: HGNC:HGNC:8994 xref: UniGene:Hs.655131 xref: UniGene:Hs.701421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043552 ! PI51A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014242 name: RPL23_human def: "60S ribosomal protein L23 gene" [UniProtKB:P62829] xref: EMBL:AB061827 xref: EMBL:BC010114 xref: EMBL:BC062716 xref: EMBL:BC104651 xref: EMBL:BC106061 xref: EMBL:X52839 xref: EMBL:X55954 xref: HGNC:HGNC:10316 xref: UniGene:Hs.406300 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043592 ! RL23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014244 name: SPSB1_human def: "SPRY domain-containing SOCS box protein 1 gene" [UniProtKB:Q96BD6] synonym: "SSB1" EXACT [UniProtKB:Q96BD6] xref: EMBL:AB209559 xref: EMBL:AF403026 xref: EMBL:AK026046 xref: EMBL:AL008734 xref: EMBL:AL358252 xref: EMBL:BC005852 xref: EMBL:BC015711 xref: EMBL:CH471130 xref: HGNC:HGNC:30628 xref: UniGene:Hs.705454 xref: UniGene:Hs.8261 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043708 ! SPSB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014245 name: SPSB2_human def: "SPRY domain-containing SOCS box protein 2 gene" [UniProtKB:Q99619] synonym: "GRCC9" EXACT [UniProtKB:Q99619] synonym: "SSB2" EXACT [UniProtKB:Q99619] xref: EMBL:AF403027 xref: EMBL:BC002983 xref: EMBL:BC071933 xref: EMBL:U47924 xref: HGNC:HGNC:29522 xref: UniGene:Hs.479856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043707 ! SPSB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014246 name: SPSB3_human def: "SPRY domain-containing SOCS box protein 3 gene" [UniProtKB:Q6PJ21] synonym: "SSB3" EXACT [UniProtKB:Q6PJ21] xref: EMBL:AE006639 xref: EMBL:AF403028 xref: EMBL:AK057850 xref: EMBL:BC007588 xref: EMBL:BC024244 xref: EMBL:BC041897 xref: EMBL:BC047441 xref: EMBL:CH471112 xref: HGNC:HGNC:30629 xref: UniGene:Hs.592080 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043529 ! SPSB3_HUMAN relationship: codes_for CCO:B0043530 ! Q96LS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014247 name: SPSB4_human def: "SPRY domain-containing SOCS box protein 4 gene" [UniProtKB:Q96A44] synonym: "SSB4" EXACT [UniProtKB:Q96A44] xref: EMBL:AF403029 xref: EMBL:AK056367 xref: EMBL:BC008324 xref: HGNC:HGNC:30630 xref: UniGene:Hs.655112 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043706 ! SPSB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014248 name: TTF1_human def: "Transcription termination factor 1 gene" [UniProtKB:Q15361] xref: EMBL:AL353701 xref: EMBL:BC050734 xref: EMBL:BC062692 xref: EMBL:BC104639 xref: EMBL:BC127669 xref: EMBL:BC127670 xref: EMBL:BC143048 xref: EMBL:BC143049 xref: EMBL:X83973 xref: HGNC:HGNC:12397 xref: UniGene:Hs.54780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043733 ! TTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014250 name: UBE2E3_human def: "Ubiquitin-conjugating enzyme E2 E3 gene" [UniProtKB:Q969T4] synonym: "UBCE4" EXACT [UniProtKB:Q969T4] synonym: "UBCH9" EXACT [UniProtKB:Q969T4] xref: EMBL:AB017644 xref: EMBL:AC104076 xref: EMBL:AF085362 xref: EMBL:AF136176 xref: EMBL:BC003554 xref: EMBL:BC092407 xref: EMBL:BT019345 xref: HGNC:HGNC:12479 xref: UniGene:Hs.470804 xref: UniGene:Hs.567831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043535 ! UB2E3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014259 name: CREBBP variant protein_human def: "CREBBP variant protein gene" [UniProtKB:Q4LE28] xref: EMBL:AB210043 xref: HGNC:HGNC:2348 xref: UniGene:Hs.459759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024549 ! Q4LE28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014341 name: AIM2_human def: "Interferon-inducible protein AIM2 gene" [UniProtKB:O14862] xref: EMBL:AF024714 xref: EMBL:AK292042 xref: EMBL:AL359753 xref: EMBL:BC010940 xref: HGNC:HGNC:357 xref: UniGene:Hs.281898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043820 ! AIM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014342 name: BBS4_human def: "Bardet-Biedl syndrome 4 protein gene" [UniProtKB:Q96RK4] xref: EMBL:AF359281 xref: EMBL:AK075321 xref: EMBL:AY457143 xref: EMBL:BC008923 xref: EMBL:BC027624 xref: HGNC:HGNC:969 xref: UniGene:Hs.208681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043836 ! BBS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014343 name: CHTF8_human def: "Chromosome transmission fidelity protein 8 homolog gene" [UniProtKB:Q8WV66] synonym: "CTF8" EXACT [UniProtKB:Q8WV66] xref: EMBL:AC009027 xref: EMBL:BC018700 xref: UniGene:Hs.85962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0041262 ! CTF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014344 name: DLGAP5_human def: "Disks large-associated protein 5 gene" [UniProtKB:Q15398] synonym: "DLG7" EXACT [UniProtKB:Q15398] synonym: "KIAA0008" EXACT [UniProtKB:Q15398] xref: EMBL:AB076695 xref: EMBL:BC010658 xref: EMBL:BC016276 xref: EMBL:BT007344 xref: EMBL:D13633 xref: HGNC:HGNC:16864 xref: UniGene:Hs.77695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0001807 ! DLGP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014345 name: EDN1_human def: "Endothelin-1 precursor gene" [UniProtKB:P05305] xref: EMBL:AY434104 xref: EMBL:BC009720 xref: EMBL:J05008 xref: EMBL:M25377 xref: EMBL:M25378 xref: EMBL:M25379 xref: EMBL:M25380 xref: EMBL:M25549 xref: EMBL:S56805 xref: EMBL:Y00749 xref: EMBL:Z98050 xref: HGNC:HGNC:3176 xref: UniGene:Hs.511899 xref: UniGene:Hs.700715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043822 ! EDN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014346 name: EDN3_human def: "Endothelin-3 precursor gene" [UniProtKB:P14138] xref: EMBL:AL035250 xref: EMBL:AY444503 xref: EMBL:BC008876 xref: EMBL:BT007085 xref: EMBL:J05081 xref: EMBL:X52001 xref: HGNC:HGNC:3178 xref: UniGene:Hs.1408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043823 ! EDN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014347 name: EIF3CL_human def: "Eukaryotic translation initiation factor 3 subunit C gene" [UniProtKB:Q99613] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026271 ! EIF3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014348 name: FMN2_human def: "Formin-2 gene" [UniProtKB:Q9NZ56] xref: EMBL:AB209153 xref: EMBL:AF218941 xref: EMBL:AF218942 xref: EMBL:AL359918 xref: EMBL:AL513342 xref: EMBL:AL590490 xref: EMBL:AL646016 xref: HGNC:HGNC:14074 xref: UniGene:Hs.24889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043838 ! FMN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014349 name: HHEX_human def: "Hematopoietically-expressed homeobox protein HHEX gene" [UniProtKB:Q03014] synonym: "HEX" EXACT [UniProtKB:Q03014] synonym: "PRH" EXACT [UniProtKB:Q03014] synonym: "PRHX" EXACT [UniProtKB:Q03014] xref: EMBL:BC014336 xref: EMBL:BC015110 xref: EMBL:BC050638 xref: EMBL:L16499 xref: EMBL:X67235 xref: EMBL:Z21533 xref: HGNC:HGNC:4901 xref: UniGene:Hs.118651 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043827 ! HHEX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014350 name: HNRNPH1_human def: "Heterogeneous nuclear ribonucleoprotein H gene" [UniProtKB:P31943] synonym: "HNRPH" EXACT [UniProtKB:P31943] synonym: "HNRPH1" EXACT [UniProtKB:P31943] xref: EMBL:BC001348 xref: EMBL:CR456778 xref: EMBL:L22009 xref: HGNC:HGNC:5041 xref: UniGene:Hs.604001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005732 ! HNRH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014351 name: HNRNPH3_human def: "Heterogeneous nuclear ribonucleoprotein H3 gene" [UniProtKB:P31942] synonym: "HNRPH3" EXACT [UniProtKB:P31942] xref: EMBL:AF132360 xref: EMBL:AF132361 xref: EMBL:AF132362 xref: EMBL:AF132363 xref: EMBL:AF132364 xref: EMBL:AL117395 xref: EMBL:BC004511 xref: EMBL:BC039824 xref: EMBL:L32610 xref: HGNC:HGNC:5043 xref: UniGene:Hs.699337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0006277 ! HNRH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014352 name: HNRNPD_human def: "Heterogeneous nuclear ribonucleoprotein D0 gene" [UniProtKB:Q14103] synonym: "AUF1" EXACT [UniProtKB:Q14103] synonym: "HNRPD" EXACT [UniProtKB:Q14103] xref: EMBL:AC124016 xref: EMBL:AF026126 xref: EMBL:AF039575 xref: EMBL:BC002401 xref: EMBL:BC023977 xref: EMBL:BC026015 xref: EMBL:D55671 xref: EMBL:D55672 xref: EMBL:D55673 xref: EMBL:D55674 xref: EMBL:M94630 xref: EMBL:X03910 xref: HGNC:HGNC:5036 xref: UniGene:Hs.480073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005686 ! HNRPD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014353 name: HNRNPF_human def: "Heterogeneous nuclear ribonucleoprotein F gene" [UniProtKB:P52597] synonym: "HNRPF" EXACT [UniProtKB:P52597] xref: EMBL:AL512654 xref: EMBL:BC001432 xref: EMBL:BC004254 xref: EMBL:BC015580 xref: EMBL:BC016736 xref: EMBL:BC106008 xref: EMBL:L28010 xref: HGNC:HGNC:5039 xref: UniGene:Hs.701075 xref: UniGene:Hs.808 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005814 ! HNRPF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014354 name: HNRNPK_human def: "Heterogeneous nuclear ribonucleoprotein K gene" [UniProtKB:P61978] synonym: "HNRPK" EXACT [UniProtKB:P61978] xref: EMBL:AB209562 xref: EMBL:AL354733 xref: EMBL:BC000355 xref: EMBL:BC014980 xref: EMBL:CH471089 xref: EMBL:S74678 xref: EMBL:X72727 xref: HGNC:HGNC:5044 xref: UniGene:Hs.695973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005235 ! HNRPK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014355 name: PYHIN1_human def: "Pyrin and HIN domain-containing protein 1 gene" [UniProtKB:Q6K0P9] synonym: "IFIX" EXACT [UniProtKB:Q6K0P9] xref: EMBL:AL359753 xref: EMBL:AY185344 xref: EMBL:AY185345 xref: EMBL:AY185346 xref: EMBL:AY185347 xref: EMBL:BC020822 xref: EMBL:BC090944 xref: EMBL:BC139741 xref: EMBL:CH471121 xref: HGNC:HGNC:28894 xref: UniGene:Hs.380250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043828 ! IFIX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014356 name: IGF1_human def: "Insulin-like growth factor IA precursor gene" [UniProtKB:P01343] synonym: "IBP1" EXACT [UniProtKB:P01343] xref: EMBL:AY260957 xref: EMBL:M11568 xref: EMBL:M12659 xref: EMBL:M14153 xref: EMBL:M14154 xref: EMBL:M14155 xref: EMBL:M14156 xref: EMBL:M27544 xref: EMBL:X00173 xref: EMBL:X03420 xref: EMBL:X03421 xref: EMBL:X03422 xref: EMBL:X03563 xref: EMBL:X56773 xref: EMBL:X56774 xref: EMBL:X57025 xref: HGNC:HGNC:5464 xref: UniGene:Hs.160562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043821 ! IGF1B_HUMAN relationship: codes_for CCO:B0054853 ! IGF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014357 name: IL12B_human def: "Interleukin-12 subunit beta precursor gene" [UniProtKB:P29460] synonym: "NKSF2" EXACT [UniProtKB:P29460] xref: EMBL:AF180563 xref: EMBL:AF512686 xref: EMBL:AY008847 xref: EMBL:BC067498 xref: EMBL:BC067499 xref: EMBL:BC067500 xref: EMBL:BC067501 xref: EMBL:BC067502 xref: EMBL:BC074723 xref: EMBL:M65272 xref: EMBL:M65290 xref: HGNC:HGNC:5970 xref: UniGene:Hs.674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043824 ! IL12B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014358 name: LPAR2_human def: "Lysophosphatidic acid receptor 2 gene" [UniProtKB:Q9HBW0] synonym: "EDG4" EXACT [UniProtKB:Q9HBW0] synonym: "LPA2" EXACT [UniProtKB:Q9HBW0] xref: EMBL:AC002306 xref: EMBL:AF011466 xref: EMBL:AF197929 xref: EMBL:AF233092 xref: EMBL:AY322548 xref: EMBL:BC025695 xref: HGNC:HGNC:3168 xref: UniGene:Hs.122575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043866 ! LPAR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014359 name: LPAR4_human def: "Lysophosphatidic acid receptor 4 gene" [UniProtKB:Q99677] synonym: "GPR23" EXACT [UniProtKB:Q99677] synonym: "LPA4" EXACT [UniProtKB:Q99677] synonym: "P2RY9" EXACT [UniProtKB:Q99677] xref: EMBL:AF005419 xref: EMBL:AL590083 xref: EMBL:AY301274 xref: EMBL:BC069996 xref: EMBL:BC074722 xref: EMBL:BC095538 xref: EMBL:U66578 xref: EMBL:U90322 xref: EMBL:U90323 xref: HGNC:HGNC:4478 xref: UniGene:Hs.522701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043867 ! LPAR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014360 name: C9orf127_human def: "Protein NGX6 gene" [UniProtKB:A6NDV4] synonym: "NGX6" EXACT [UniProtKB:A6NDV4] xref: EMBL:AF070572 xref: EMBL:AF149297 xref: EMBL:AF188239 xref: EMBL:AL133410 xref: EMBL:BC041377 xref: EMBL:BC098265 xref: EMBL:BC098296 xref: EMBL:BC099733 xref: EMBL:CH471071 xref: HGNC:HGNC:21427 xref: UniGene:Hs.493808 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043817 ! NGX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014361 name: PSRC1_human def: "Proline/serine-rich coiled-coil protein 1 gene" [UniProtKB:Q6PGN9] synonym: "DDA3" EXACT [UniProtKB:Q6PGN9] synonym: "FP3214" EXACT [UniProtKB:Q6PGN9] xref: EMBL:AF223000 xref: EMBL:AF322891 xref: EMBL:AF447874 xref: EMBL:AK126567 xref: EMBL:AL390252 xref: EMBL:BC056909 xref: HGNC:HGNC:24472 xref: UniGene:Hs.405925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043829 ! PSRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014362 name: RPS15A_human def: "40S ribosomal protein S15a gene" [UniProtKB:P62244] synonym: "OK/SW-cl.82" EXACT [UniProtKB:P62244] xref: EMBL:AB007154 xref: EMBL:AB062400 xref: EMBL:AY208299 xref: EMBL:BC001697 xref: EMBL:BC030569 xref: EMBL:BC046113 xref: EMBL:BC105273 xref: EMBL:BC105292 xref: EMBL:X62691 xref: EMBL:X84407 xref: HGNC:HGNC:10389 xref: UniGene:Hs.370504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043825 ! RS15A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014363 name: SBDS_human def: "Ribosome maturation protein SBDS gene" [UniProtKB:Q9Y3A5] synonym: "CGI-97" EXACT [UniProtKB:Q9Y3A5] xref: EMBL:AF151855 xref: EMBL:AK001779 xref: EMBL:AY169963 xref: EMBL:BC065700 xref: HGNC:HGNC:19440 xref: UniGene:Hs.110445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025212 ! SBDS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014364 name: SLC5A8_human def: "Sodium-coupled monocarboxylate transporter 1 gene" [UniProtKB:Q8N695] synonym: "AIT" EXACT [UniProtKB:Q8N695] synonym: "SMCT" EXACT [UniProtKB:Q8N695] synonym: "SMCT1" EXACT [UniProtKB:Q8N695] xref: EMBL:AF536216 xref: EMBL:AF536217 xref: EMBL:AY081220 xref: EMBL:BC110492 xref: EMBL:CH471054 xref: HGNC:HGNC:19119 xref: UniGene:Hs.444536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043833 ! SC5A8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014365 name: SEPT13_human def: "Septin-13 gene" [UniProtKB:A8MT51] synonym: "SEPT7B" EXACT [UniProtKB:A8MT51] xref: EMBL:AC091439 xref: EMBL:AC096582 xref: EMBL:AL832059 xref: EMBL:BC092503 xref: HGNC:HGNC:32339 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028285 ! SEP13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014366 name: SMAD3_human def: "Mothers against decapentaplegic homolog 3 gene" [UniProtKB:P84022] synonym: "MADH3" EXACT [UniProtKB:P84022] xref: EMBL:AB004930 xref: EMBL:AF025293 xref: EMBL:AF025294 xref: EMBL:AF025295 xref: EMBL:AF025296 xref: EMBL:AF025297 xref: EMBL:AF025298 xref: EMBL:AF025299 xref: EMBL:AF025300 xref: EMBL:BC050743 xref: EMBL:U68019 xref: EMBL:U76622 xref: HGNC:HGNC:6769 xref: UniGene:Hs.618504 xref: UniGene:Hs.702172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043826 ! SMAD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014367 name: SNAPIN_human def: "SNARE-associated protein Snapin gene" [UniProtKB:O95295] synonym: "SNAP25BP" EXACT [UniProtKB:O95295] synonym: "SNAPAP" EXACT [UniProtKB:O95295] xref: EMBL:AF086837 xref: EMBL:AK024555 xref: EMBL:BC000761 xref: EMBL:BC004494 xref: EMBL:BT006753 xref: HGNC:HGNC:17145 xref: UniGene:Hs.32018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043870 ! SNAPN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014368 name: ST20_human def: "Suppressor of tumorigenicity protein 20 gene" [UniProtKB:Q9HBF5] synonym: "HCCS1" EXACT [UniProtKB:Q9HBF5] xref: EMBL:AF249277 xref: HGNC:HGNC:33520 xref: UniGene:Hs.459049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043837 ! ST20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014369 name: URG4_human def: "Protein URG4 gene" [UniProtKB:Q8TCY9] synonym: "KIAA1507" EXACT [UniProtKB:Q8TCY9] xref: EMBL:AB040940 xref: EMBL:AC004985 xref: EMBL:AK000661 xref: EMBL:AL833744 xref: EMBL:AY078404 xref: EMBL:BC018426 xref: EMBL:BX640797 xref: EMBL:CR749398 xref: UniGene:Hs.284286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043834 ! URG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014370 name: ZBTB7C_human def: "Zinc finger and BTB domain-containing protein 7C gene" [UniProtKB:A1YPR0] synonym: "APM1" EXACT [UniProtKB:A1YPR0] synonym: "ZBTB36" EXACT [UniProtKB:A1YPR0] xref: EMBL:EF120357 xref: EMBL:Y14591 xref: HGNC:HGNC:31700 xref: UniGene:Hs.515388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043816 ! ZBT7C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014371 name: ZNF830_human def: "Zinc finger protein 830 gene" [UniProtKB:Q96NB3] synonym: "CCDC16" EXACT [UniProtKB:Q96NB3] xref: EMBL:AK055707 xref: EMBL:BC002913 xref: EMBL:BC009044 xref: EMBL:BC011584 xref: HGNC:HGNC:28291 xref: UniGene:Hs.413678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002051 ! ZN830_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014372 name: IFFO_human def: "IFFO protein gene" [UniProtKB:Q6P593] xref: EMBL:BC063004 xref: UniGene:Hs.15243 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005963 ! Q6P593_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014613 name: AAMP_human def: "Angio-associated migratory cell protein gene" [UniProtKB:Q13685] xref: EMBL:BC008809 xref: EMBL:BC020244 xref: EMBL:BC039866 xref: EMBL:CR456755 xref: EMBL:M95627 xref: HGNC:HGNC:18 xref: UniGene:Hs.83347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050226 ! AAMP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014620 name: SCIN_human def: "Adseverin gene" [UniProtKB:Q9Y6U3] synonym: "KIAA1905" EXACT [UniProtKB:Q9Y6U3] xref: EMBL:AB067492 xref: EMBL:AC005281 xref: EMBL:AF276507 xref: EMBL:AK027778 xref: EMBL:AK075123 xref: EMBL:BC021090 xref: HGNC:HGNC:21695 xref: UniGene:Hs.633359 xref: UniGene:Hs.655515 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051620 ! ADSV_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014622 name: AHRR_human def: "Aryl hydrocarbon receptor repressor gene" [UniProtKB:A9YTQ3] synonym: "KIAA1234" EXACT [UniProtKB:A9YTQ3] xref: EMBL:AB033060 xref: EMBL:AF293629 xref: EMBL:AF293630 xref: EMBL:AF293631 xref: EMBL:AF293632 xref: EMBL:AF293633 xref: EMBL:AF293634 xref: EMBL:AF293635 xref: EMBL:AF293636 xref: EMBL:AF293637 xref: EMBL:AF293638 xref: EMBL:AF293639 xref: EMBL:BC151852 xref: EMBL:BC152406 xref: EMBL:CH471235 xref: EMBL:EU293605 xref: HGNC:HGNC:346 xref: UniGene:Hs.50823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050348 ! AHRR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014623 name: IGFALS_human def: "Insulin-like growth factor-binding protein complex acid labile chain precursor gene" [UniProtKB:P35858] synonym: "ALS" EXACT [UniProtKB:P35858] xref: EMBL:AF192554 xref: EMBL:AL031724 xref: EMBL:M86826 xref: HGNC:HGNC:5468 xref: UniGene:Hs.839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048872 ! ALS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014633 name: ARID5B_human def: "AT-rich interactive domain-containing protein 5B gene" [UniProtKB:Q14865] synonym: "DESRT" EXACT [UniProtKB:Q14865] synonym: "MRF2" EXACT [UniProtKB:Q14865] xref: EMBL:AC067742 xref: EMBL:AK024803 xref: EMBL:AL671972 xref: EMBL:BC036831 xref: EMBL:BX537690 xref: EMBL:BX641020 xref: EMBL:M73837 xref: HGNC:HGNC:17362 xref: UniGene:Hs.535297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050679 ! ARI5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014634 name: ARPC2_human def: "Actin-related protein 2/3 complex subunit 2 gene" [UniProtKB:O15144] synonym: "ARC34" EXACT [UniProtKB:O15144] synonym: "PRO2446" EXACT [UniProtKB:O15144] xref: EMBL:AF006085 xref: EMBL:AF116702 xref: EMBL:BC000590 xref: EMBL:BT006898 xref: EMBL:U50523 xref: HGNC:HGNC:705 xref: UniGene:Hs.529303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024099 ! ARPC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014635 name: ARS2_human def: "Arsenite-resistance protein 2 gene" [UniProtKB:Q9BXP5] synonym: "ASR2" EXACT [UniProtKB:Q9BXP5] xref: EMBL:AC011895 xref: EMBL:AF082871 xref: EMBL:AF312032 xref: EMBL:AL096723 xref: EMBL:BC000082 xref: EMBL:BC109117 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: UniGene:Hs.111801 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050587 ! ARS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014638 name: ATXN3L_human def: "Putative ataxin-3-like protein gene" [UniProtKB:Q9H3M9] synonym: "MJDL" EXACT [UniProtKB:Q9H3M9] xref: EMBL:AB050195 xref: EMBL:AC004674 xref: HGNC:HGNC:24173 xref: UniGene:Hs.382641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049686 ! ATX3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014639 name: ATXN3_human def: "Ataxin-3 gene" [UniProtKB:P54252] synonym: "ATX3" EXACT [UniProtKB:P54252] synonym: "MJD" EXACT [UniProtKB:P54252] synonym: "MJD1" EXACT [UniProtKB:P54252] synonym: "SCA3" EXACT [UniProtKB:P54252] xref: EMBL:AB038653 xref: EMBL:AB050194 xref: EMBL:AL049872 xref: EMBL:BC033711 xref: EMBL:CH471061 xref: EMBL:EU009923 xref: EMBL:S75313 xref: EMBL:U64820 xref: EMBL:U64821 xref: EMBL:U64822 xref: HGNC:HGNC:7106 xref: UniGene:Hs.532632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049689 ! ATX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014640 name: AVIL_human def: "Advillin gene" [UniProtKB:O75366] xref: EMBL:AF041449 xref: HGNC:HGNC:14188 xref: UniGene:Hs.584854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051612 ! AVIL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014645 name: MTHFD1_human def: "C-1-tetrahydrofolate synthase, cytoplasmic gene" [UniProtKB:P11586] synonym: "MTHFC" EXACT [UniProtKB:P11586] synonym: "MTHFD" EXACT [UniProtKB:P11586] xref: EMBL:BC001014 xref: EMBL:BC009806 xref: EMBL:BC050420 xref: EMBL:J04031 xref: HGNC:HGNC:7432 xref: UniGene:Hs.652308 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050859 ! C1TC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014647 name: CIITA_human def: "MHC class II transactivator gene" [UniProtKB:P33076] synonym: "MHC2TA" EXACT [UniProtKB:P33076] xref: EMBL:AY084054 xref: EMBL:CH471112 xref: EMBL:EF064747 xref: EMBL:U18259 xref: EMBL:X74301 xref: HGNC:HGNC:7067 xref: UniGene:Hs.701991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051380 ! C2TA_HUMAN relationship: codes_for CCO:B0051381 ! A0N0N9_HUMAN relationship: codes_for CCO:B0051384 ! Q8SNB8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014648 name: C1orf149_human def: "Uncharacterized protein C1orf149 gene" [UniProtKB:Q9HAF1] xref: EMBL:AK021792 xref: EMBL:AL034379 xref: EMBL:AY211926 xref: EMBL:BC016328 xref: EMBL:BC056406 xref: EMBL:BX538212 xref: EMBL:BX640719 xref: EMBL:DQ099384 xref: HGNC:HGNC:25674 xref: UniGene:Hs.17118 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049761 ! CA149_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014652 name: CCHCR1_human def: "Coiled-coil alpha-helical rod protein 1 gene" [UniProtKB:Q8TD31] synonym: "C6orf18" EXACT [UniProtKB:Q8TD31] synonym: "HCR" EXACT [UniProtKB:Q8TD31] xref: EMBL:AB029331 xref: EMBL:AB029343 xref: EMBL:AB088104 xref: EMBL:AF216493 xref: EMBL:AK000204 xref: EMBL:AK000217 xref: EMBL:AK000533 xref: EMBL:AY029160 xref: EMBL:BA000025 xref: HGNC:HGNC:13930 xref: UniGene:Hs.485075 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050075 ! CCHCR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014653 name: CD40LG_human def: "CD40 ligand gene" [UniProtKB:P29965] synonym: "CD40L" EXACT [UniProtKB:P29965] synonym: "TNFSF5" EXACT [UniProtKB:P29965] synonym: "TRAP" EXACT [UniProtKB:P29965] xref: EMBL:BC071754 xref: EMBL:BC074950 xref: EMBL:D31797 xref: EMBL:L07414 xref: EMBL:X67878 xref: EMBL:X68550 xref: EMBL:Z15017 xref: HGNC:HGNC:11935 xref: UniGene:Hs.592244 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050340 ! CD40L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014654 name: CD72_human def: "B-cell differentiation antigen CD72 gene" [UniProtKB:P21854] xref: EMBL:BC030227 xref: EMBL:M54992 xref: HGNC:HGNC:1696 xref: UniGene:Hs.116481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050006 ! CD72_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014655 name: CEBPZ_human def: "CCAAT/enhancer-binding protein zeta gene" [UniProtKB:Q03701] synonym: "CBF2" EXACT [UniProtKB:Q03701] xref: EMBL:AC007390 xref: EMBL:BC034475 xref: EMBL:M37197 xref: HGNC:HGNC:24218 xref: UniGene:Hs.135406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024821 ! CEBPZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014672 name: CLDN7_human def: "Claudin-7 gene" [UniProtKB:O95471] synonym: "CEPTRL2" EXACT [UniProtKB:O95471] synonym: "CPETRL2" EXACT [UniProtKB:O95471] xref: EMBL:AF093823 xref: EMBL:AJ011497 xref: EMBL:BC001055 xref: EMBL:BC071844 xref: EMBL:BT006829 xref: HGNC:HGNC:2049 xref: UniGene:Hs.513915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049698 ! CLD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014675 name: CLPTM1_human def: "Cleft lip and palate transmembrane protein 1 gene" [UniProtKB:O96005] xref: EMBL:AF037338 xref: EMBL:AF037339 xref: EMBL:AK223553 xref: EMBL:BC004865 xref: EMBL:BC012359 xref: EMBL:BT007262 xref: HGNC:HGNC:2087 xref: UniGene:Hs.444441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051232 ! CLPT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014676 name: CNOT2_human def: "CCR4-NOT transcription complex subunit 2 gene" [UniProtKB:Q9NZN8] synonym: "CDC36" EXACT [UniProtKB:Q9NZN8] synonym: "HSPC131" EXACT [UniProtKB:Q9NZN8] synonym: "MSTP046" EXACT [UniProtKB:Q9NZN8] synonym: "NOT2" EXACT [UniProtKB:Q9NZN8] xref: EMBL:AF044215 xref: EMBL:AF113226 xref: EMBL:AF161480 xref: EMBL:AF180473 xref: EMBL:AK000662 xref: EMBL:AL137674 xref: EMBL:BC002597 xref: EMBL:BC011826 xref: EMBL:BX641116 xref: HGNC:HGNC:7878 xref: UniGene:Hs.133350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049757 ! CNOT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014677 name: CNOT7_human def: "CCR4-NOT transcription complex subunit 7 gene" [UniProtKB:Q9UIV1] synonym: "CAF1" EXACT [UniProtKB:Q9UIV1] xref: EMBL:AF086915 xref: EMBL:BC060852 xref: EMBL:BC070187 xref: EMBL:CH471080 xref: EMBL:L46722 xref: HGNC:HGNC:14101 xref: UniGene:Hs.598387 xref: UniGene:Hs.645009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050528 ! CNOT7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014678 name: CNOT8_human def: "CCR4-NOT transcription complex subunit 8 gene" [UniProtKB:Q9UFF9] synonym: "CALIF" EXACT [UniProtKB:Q9UFF9] synonym: "POP2" EXACT [UniProtKB:Q9UFF9] xref: EMBL:AF053318 xref: EMBL:AF087844 xref: EMBL:AF180476 xref: EMBL:AK025358 xref: EMBL:AL122045 xref: EMBL:BC017366 xref: EMBL:BT006857 xref: HGNC:HGNC:9207 xref: UniGene:Hs.26703 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050534 ! CNOT8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014680 name: CNPY4_human def: "Protein canopy homolog 4 precursor gene" [UniProtKB:Q8N129] synonym: "PSEC0237" EXACT [UniProtKB:Q8N129] synonym: "UNQ1909/PRO4354" EXACT [UniProtKB:Q8N129] xref: EMBL:AK075537 xref: EMBL:AY359100 xref: EMBL:BC019903 xref: EMBL:BC032339 xref: EMBL:CH236956 xref: HGNC:HGNC:28631 xref: UniGene:Hs.632293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051192 ! CNPY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014681 name: CNTF_human def: "Ciliary neurotrophic factor gene" [UniProtKB:P26441] xref: EMBL:BC068030 xref: EMBL:BC074963 xref: EMBL:BC074964 xref: EMBL:X55889 xref: EMBL:X55890 xref: EMBL:X60477 xref: EMBL:X60478 xref: EMBL:X60542 xref: HGNC:HGNC:2169 xref: UniGene:Hs.632114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049425 ! CNTF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014686 name: CRIP1_human def: "Cysteine-rich protein 1 gene" [UniProtKB:P50238] synonym: "CRIP" EXACT [UniProtKB:P50238] xref: EMBL:BC002738 xref: EMBL:U09770 xref: EMBL:U58630 xref: HGNC:HGNC:2360 xref: UniGene:Hs.70327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048870 ! CRIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014687 name: CRIP2_human def: "Cysteine-rich protein 2 gene" [UniProtKB:P52943] synonym: "CRP2" EXACT [UniProtKB:P52943] xref: EMBL:BC000434 xref: EMBL:BC001931 xref: EMBL:BC034151 xref: EMBL:BT019911 xref: EMBL:D42123 xref: EMBL:U36190 xref: HGNC:HGNC:2361 xref: UniGene:Hs.534309 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048868 ! CRIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014689 name: CTGF_human def: "Connective tissue growth factor precursor gene" [UniProtKB:P29279] synonym: "CCN2" EXACT [UniProtKB:P29279] synonym: "HCS24" EXACT [UniProtKB:P29279] synonym: "IGFBP8" EXACT [UniProtKB:P29279] xref: EMBL:AF316366 xref: EMBL:AF316367 xref: EMBL:AF316368 xref: EMBL:AL354866 xref: EMBL:AY395801 xref: EMBL:AY550024 xref: EMBL:BT019794 xref: EMBL:BT019795 xref: EMBL:CR541759 xref: EMBL:M92934 xref: EMBL:U14750 xref: EMBL:X78947 xref: EMBL:X92511 xref: HGNC:HGNC:2500 xref: UniGene:Hs.591346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021696 ! CTGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014694 name: CUX2_human def: "Cut-like homeobox 2 gene" [UniProtKB:A7E2Y4] xref: EMBL:BC151245 xref: UniGene:Hs.124953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050234 ! A7E2Y4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014697 name: CSDA_human def: "DNA-binding protein A gene" [UniProtKB:P16989] synonym: "DBPA" EXACT [UniProtKB:P16989] xref: EMBL:BC008801 xref: EMBL:BC015564 xref: EMBL:BC021926 xref: EMBL:L29064 xref: EMBL:L29065 xref: EMBL:L29066 xref: EMBL:L29067 xref: EMBL:L29068 xref: EMBL:L29069 xref: EMBL:L29070 xref: EMBL:L29071 xref: EMBL:M24069 xref: EMBL:X72712 xref: EMBL:X95325 xref: HGNC:HGNC:2428 xref: UniGene:Hs.221889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049892 ! DBPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014709 name: EHMT2_human def: "Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 gene" [UniProtKB:Q96KQ7] synonym: "BAT8" EXACT [UniProtKB:Q96KQ7] synonym: "C6orf30" EXACT [UniProtKB:Q96KQ7] synonym: "G9A" EXACT [UniProtKB:Q96KQ7] synonym: "KMT1C" EXACT [UniProtKB:Q96KQ7] synonym: "NG36" EXACT [UniProtKB:Q96KQ7] xref: EMBL:AF134726 xref: EMBL:AJ315532 xref: EMBL:AK056936 xref: EMBL:BA000025 xref: EMBL:BC002686 xref: EMBL:BC009351 xref: EMBL:BC018718 xref: EMBL:BC020970 xref: EMBL:X69838 xref: HGNC:HGNC:14129 xref: UniGene:Hs.520038 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051938 ! EHMT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014710 name: ELP2_human def: "Elongator complex protein 2 gene" [UniProtKB:Q6IA86] synonym: "STATIP1" EXACT [UniProtKB:Q6IA86] xref: EMBL:AF332505 xref: EMBL:AF403223 xref: EMBL:AK001741 xref: EMBL:AK022709 xref: EMBL:AK222791 xref: EMBL:BC009211 xref: EMBL:BC032553 xref: EMBL:CR457269 xref: HGNC:HGNC:18248 xref: UniGene:Hs.8739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048582 ! ELP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014716 name: EPPK1_human def: "Epiplakin gene" [UniProtKB:P58107] synonym: "EPIPL" EXACT [UniProtKB:P58107] xref: EMBL:AB051895 xref: EMBL:AB107036 xref: HGNC:HGNC:15577 xref: UniGene:Hs.200412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050501 ! EPIPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014728 name: FAM13A1_human def: "FAM13A1_v2 protein gene" [UniProtKB:Q24JP0] xref: EMBL:BN000265 xref: HGNC:HGNC:19367 xref: UniGene:Hs.702033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049905 ! Q24JP0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014731 name: FIBP_human def: "Acidic fibroblast growth factor intracellular-binding protein gene" [UniProtKB:O43427] xref: EMBL:AF010187 xref: EMBL:AF171944 xref: EMBL:AF171945 xref: EMBL:AF171946 xref: EMBL:AF250391 xref: EMBL:AF250392 xref: EMBL:BC014388 xref: EMBL:BC017448 xref: EMBL:CR456749 xref: HGNC:HGNC:3705 xref: UniGene:Hs.7768 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051370 ! FIBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014732 name: FOXO3_human def: "Forkhead box protein O3 gene" [UniProtKB:O43524] synonym: "FKHRL1" EXACT [UniProtKB:O43524] synonym: "FOXO3A" EXACT [UniProtKB:O43524] xref: EMBL:AF032886 xref: EMBL:AJ001589 xref: EMBL:AJ001590 xref: EMBL:AL365509 xref: EMBL:AL391646 xref: EMBL:BC020227 xref: EMBL:BC021224 xref: EMBL:BC068552 xref: HGNC:HGNC:3821 xref: UniGene:Hs.220950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050345 ! FOXO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014733 name: FOXS1_human def: "Forkhead box protein S1 gene" [UniProtKB:O43638] synonym: "FKHL18" EXACT [UniProtKB:O43638] synonym: "FREAC10" EXACT [UniProtKB:O43638] xref: EMBL:AF042831 xref: EMBL:AL160175 xref: EMBL:BC013408 xref: EMBL:BT009768 xref: HGNC:HGNC:3735 xref: UniGene:Hs.516971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049072 ! FOXS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014738 name: GABARAPL1_human def: "Gamma-aminobutyric acid receptor-associated protein-like 1 gene" [UniProtKB:Q9H0R8] synonym: "GEC1" EXACT [UniProtKB:Q9H0R8] xref: EMBL:AF087847 xref: EMBL:AF287012 xref: EMBL:AL136676 xref: EMBL:BC009309 xref: EMBL:BC028315 xref: EMBL:CH471094 xref: EMBL:CR533480 xref: HGNC:HGNC:4068 xref: UniGene:Hs.524250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051353 ! GBRL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014739 name: GABARAPL2_human def: "Gamma-aminobutyric acid receptor-associated protein-like 2 gene" [UniProtKB:P60520] synonym: "FLC3A" EXACT [UniProtKB:P60520] synonym: "GEF2" EXACT [UniProtKB:P60520] xref: EMBL:AB030710 xref: EMBL:AF077046 xref: EMBL:AF087848 xref: EMBL:AJ010569 xref: EMBL:BC005985 xref: EMBL:BC014594 xref: EMBL:BC029601 xref: HGNC:HGNC:13291 xref: UniGene:Hs.461379 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051349 ! GBRL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014741 name: GCH1_human def: "GTP cyclohydrolase 1 gene" [UniProtKB:P30793] synonym: "DYT5" EXACT [UniProtKB:P30793] synonym: "GCH" EXACT [UniProtKB:P30793] xref: EMBL:BC025415 xref: EMBL:L29478 xref: EMBL:S43856 xref: EMBL:S44049 xref: EMBL:S44053 xref: EMBL:U19256 xref: EMBL:U19257 xref: EMBL:U19258 xref: EMBL:U19259 xref: EMBL:U19523 xref: EMBL:U66095 xref: EMBL:U66097 xref: EMBL:Z16418 xref: EMBL:Z29433 xref: EMBL:Z29434 xref: EMBL:Z30952 xref: HGNC:HGNC:4193 xref: UniGene:Hs.86724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050722 ! GCH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014742 name: GSN_human def: "Gelsolin precursor gene" [UniProtKB:P06396] xref: EMBL:BC017491 xref: EMBL:BC026033 xref: EMBL:X04412 xref: HGNC:HGNC:4620 xref: UniGene:Hs.522373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051611 ! GELS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014745 name: GNA11_human def: "Guanine nucleotide-binding protein subunit alpha-11 gene" [UniProtKB:P29992] synonym: "GA11" EXACT [UniProtKB:P29992] xref: EMBL:AC005262 xref: EMBL:AF011497 xref: EMBL:AF493900 xref: EMBL:BC089041 xref: EMBL:BC096225 xref: EMBL:BC096226 xref: EMBL:BC096227 xref: EMBL:CR457004 xref: EMBL:L40630 xref: EMBL:M69013 xref: HGNC:HGNC:4379 xref: UniGene:Hs.654784 xref: UniGene:Hs.655202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030251 ! GNA11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014746 name: GNA14_human def: "Guanine nucleotide-binding protein subunit alpha-14 gene" [UniProtKB:O95837] xref: EMBL:AF105201 xref: EMBL:AF493903 xref: EMBL:BC027886 xref: HGNC:HGNC:4382 xref: UniGene:Hs.657795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030261 ! GNA14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014747 name: GNAI3_human def: "Guanine nucleotide-binding protein G(k) subunit alpha gene" [UniProtKB:P08754] xref: EMBL:AF493907 xref: EMBL:BC025285 xref: EMBL:BT019974 xref: EMBL:J03005 xref: EMBL:J03198 xref: EMBL:J03238 xref: EMBL:M20597 xref: EMBL:M20598 xref: EMBL:M20599 xref: EMBL:M20600 xref: EMBL:M20601 xref: EMBL:M20602 xref: EMBL:M20603 xref: EMBL:M20604 xref: EMBL:M27543 xref: HGNC:HGNC:4387 xref: UniGene:Hs.73799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030269 ! GNAI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014748 name: GNAO1_human def: "Guanine nucleotide-binding protein G(o) subunit alpha gene" [UniProtKB:P09471] xref: EMBL:AF493894 xref: EMBL:AF493895 xref: EMBL:M19182 xref: EMBL:M19184 xref: EMBL:M60156 xref: EMBL:M60157 xref: EMBL:M60158 xref: EMBL:M60159 xref: EMBL:M60160 xref: EMBL:M60161 xref: EMBL:M60162 xref: EMBL:M60163 xref: EMBL:M60164 xref: EMBL:Y18213 xref: HGNC:HGNC:4389 xref: UniGene:Hs.695994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049381 ! GNAO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014749 name: GNAQ_human def: "Guanine nucleotide binding protein (G protein), q polypeptide gene" [UniProtKB:B1AM21] synonym: "RP11-494N1.1-002" EXACT [UniProtKB:B1AM21] xref: EMBL:AL160268 xref: EMBL:AL160278 xref: EMBL:AL355535 xref: EMBL:BC057777 xref: EMBL:BC067850 xref: EMBL:BC069520 xref: EMBL:BC075096 xref: EMBL:BC075097 xref: EMBL:CH471089 xref: HGNC:HGNC:4390 xref: UniGene:Hs.269782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030243 ! Q6NT27_HUMAN relationship: codes_for CCO:B0054249 ! B1AM21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014750 name: GNAT1_human def: "Guanine nucleotide-binding protein G(t) subunit alpha-1 gene" [UniProtKB:P11488] synonym: "GNATR" EXACT [UniProtKB:P11488] xref: EMBL:AC002077 xref: EMBL:AF493908 xref: EMBL:BC095505 xref: EMBL:X15088 xref: EMBL:X63749 xref: HGNC:HGNC:4393 xref: UniGene:Hs.517978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030266 ! GNAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014751 name: GNAT2_human def: "Guanine nucleotide-binding protein G(t) subunit alpha-2 gene" [UniProtKB:P19087] synonym: "GNATC" EXACT [UniProtKB:P19087] xref: EMBL:AF493909 xref: EMBL:BC000233 xref: EMBL:D10384 xref: EMBL:Z18859 xref: HGNC:HGNC:4394 xref: UniGene:Hs.36973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030262 ! GNAT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014752 name: GNAT3_human def: "Guanine nucleotide-binding protein G(t) subunit alpha-3 gene" [UniProtKB:A8MTJ3] xref: EMBL:AC004862 xref: EMBL:CH236949 xref: HGNC:HGNC:22800 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049379 ! GNAT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014753 name: GNAZ_human def: "Guanine nucleotide-binding protein G(z) subunit alpha gene" [UniProtKB:P19086] xref: EMBL:AF493899 xref: EMBL:BC078163 xref: EMBL:BC096828 xref: EMBL:CR456495 xref: EMBL:D90150 xref: EMBL:J03260 xref: HGNC:HGNC:4395 xref: UniGene:Hs.584760 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030249 ! GNAZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014763 name: CD74_human def: "HLA class II histocompatibility antigen gamma chain gene" [UniProtKB:P04233] synonym: "DHLAG" EXACT [UniProtKB:P04233] xref: EMBL:BC018726 xref: EMBL:BT019505 xref: EMBL:K01144 xref: EMBL:M13555 xref: EMBL:M13556 xref: EMBL:M13558 xref: EMBL:M13559 xref: EMBL:M13560 xref: EMBL:X00497 xref: EMBL:X03339 xref: EMBL:X03340 xref: HGNC:HGNC:1697 xref: UniGene:Hs.436568 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049558 ! HG2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014764 name: HMG1L10_human def: "High mobility group protein 1-like 10 gene" [UniProtKB:Q9UGV6] xref: EMBL:Z95115 xref: HGNC:HGNC:4994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050276 ! HMGLX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014765 name: HMG4L_human def: "High mobility group protein B3-like gene" [UniProtKB:Q3SYE8] xref: EMBL:BC103849 xref: EMBL:BC103850 xref: EMBL:BC103851 xref: HGNC:HGNC:16240 xref: UniGene:Hs.558624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050275 ! HMG4L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014766 name: HMGB2_human def: "High mobility group protein B2 gene" [UniProtKB:P26583] synonym: "HMG2" EXACT [UniProtKB:P26583] xref: EMBL:BC001063 xref: EMBL:BC100019 xref: EMBL:BT019782 xref: EMBL:M83665 xref: EMBL:X62534 xref: EMBL:Z17240 xref: HGNC:HGNC:5000 xref: UniGene:Hs.434953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050294 ! HMGB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014767 name: HMGB3_human def: "High mobility group protein B3 gene" [UniProtKB:O15347] synonym: "HMG2A" EXACT [UniProtKB:O15347] synonym: "HMG4" EXACT [UniProtKB:O15347] xref: EMBL:AF003626 xref: EMBL:BC070482 xref: EMBL:Y10043 xref: HGNC:HGNC:5004 xref: UniGene:Hs.693708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050279 ! HMGB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014768 name: HMGB4_human def: "High mobility group protein B4 gene" [UniProtKB:Q8WW32] xref: EMBL:BC021180 xref: EMBL:BC070148 xref: HGNC:HGNC:24954 xref: UniGene:Hs.568628 xref: UniGene:Hs.667683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050277 ! HMGB4_HUMAN relationship: codes_for CCO:B0050288 ! Q6NSH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014769 name: ONECUT1_human def: "Hepatocyte nuclear factor 6 gene" [UniProtKB:Q9UBC0] synonym: "HNF6" EXACT [UniProtKB:Q9UBC0] synonym: "HNF6A" EXACT [UniProtKB:Q9UBC0] xref: EMBL:AF035580 xref: EMBL:AF035581 xref: EMBL:U77975 xref: EMBL:U96173 xref: EMBL:Y17739 xref: HGNC:HGNC:8138 xref: UniGene:Hs.658573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049067 ! HNF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014771 name: IDH1_human def: "Isocitrate dehydrogenase [NADP] cytoplasmic gene" [UniProtKB:O75874] synonym: "PICD" EXACT [UniProtKB:O75874] xref: EMBL:AF020038 xref: EMBL:AF113917 xref: EMBL:AL136702 xref: EMBL:BC012846 xref: EMBL:U62389 xref: HGNC:HGNC:5382 xref: UniGene:Hs.593422 xref: UniGene:Hs.705391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050696 ! IDHC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014773 name: EIF4B_human def: "Eukaryotic translation initiation factor 4B gene" [UniProtKB:P23588] xref: EMBL:AB076839 xref: EMBL:AK222528 xref: EMBL:BC073139 xref: EMBL:BC073154 xref: EMBL:BC098437 xref: EMBL:CH471054 xref: EMBL:CR456958 xref: EMBL:X55733 xref: HGNC:HGNC:3285 xref: UniGene:Hs.648394 xref: UniGene:Hs.702041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050510 ! IF4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014774 name: EIF5_human def: "Eukaryotic translation initiation factor 5 gene" [UniProtKB:P55010] xref: EMBL:AK026933 xref: EMBL:AL080102 xref: EMBL:BC007728 xref: EMBL:BC032866 xref: EMBL:U49436 xref: HGNC:HGNC:3299 xref: UniGene:Hs.433702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051549 ! IF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014776 name: IL31RA_human def: "Interleukin-31 receptor A precursor gene" [UniProtKB:Q8NI17] synonym: "CRL3" EXACT [UniProtKB:Q8NI17] synonym: "GPL" EXACT [UniProtKB:Q8NI17] synonym: "UNQ6368/PRO21073/PRO21384" EXACT [UniProtKB:Q8NI17] xref: EMBL:AC008914 xref: EMBL:AF106913 xref: EMBL:AF486620 xref: EMBL:AY358117 xref: EMBL:AY358740 xref: EMBL:AY499339 xref: EMBL:AY499340 xref: EMBL:AY499341 xref: EMBL:AY499342 xref: EMBL:BC110490 xref: HGNC:HGNC:18969 xref: UniGene:Hs.55378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048954 ! IL31R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014777 name: IPO5_human def: "Importin-5 gene" [UniProtKB:O00410] synonym: "KPNB3" EXACT [UniProtKB:O00410] synonym: "RANBP5" EXACT [UniProtKB:O00410] xref: EMBL:BC001497 xref: EMBL:BC019309 xref: EMBL:U72761 xref: EMBL:Y08890 xref: HGNC:HGNC:6402 xref: UniGene:Hs.643743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050166 ! IPO5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014778 name: IPO8_human def: "Importin-8 gene" [UniProtKB:O15397] synonym: "RANBP8" EXACT [UniProtKB:O15397] xref: EMBL:U77494 xref: HGNC:HGNC:9853 xref: UniGene:Hs.505136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050581 ! IPO8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014779 name: IRS1_human def: "Insulin receptor substrate 1 gene" [UniProtKB:P35568] xref: EMBL:BC053895 xref: EMBL:S62539 xref: EMBL:S85963 xref: HGNC:HGNC:6125 xref: UniGene:Hs.471508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051810 ! IRS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014781 name: IRS4_human def: "Insulin receptor substrate 4 gene" [UniProtKB:O14654] xref: EMBL:AF007567 xref: EMBL:AL035425 xref: EMBL:CH471120 xref: HGNC:HGNC:6128 xref: UniGene:Hs.592215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051815 ! IRS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014784 name: ITGA11_human def: "Integrin alpha-11 precursor gene" [UniProtKB:Q9UKX5] synonym: "MSTP018" EXACT [UniProtKB:Q9UKX5] xref: EMBL:AF109681 xref: EMBL:AF111799 xref: EMBL:AF137378 xref: EMBL:AL359064 xref: HGNC:HGNC:6136 xref: UniGene:Hs.436416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050191 ! ITA11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014785 name: ITGA2_human def: "Integrin alpha-2 precursor gene" [UniProtKB:P17301] synonym: "CD49B" EXACT [UniProtKB:P17301] xref: EMBL:AF512556 xref: EMBL:L24121 xref: EMBL:X17033 xref: HGNC:HGNC:6137 xref: UniGene:Hs.482077 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050196 ! ITA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014786 name: ITGAD_human def: "Integrin alpha-D precursor gene" [UniProtKB:Q13349] xref: EMBL:AF187881 xref: EMBL:U37028 xref: EMBL:U40274 xref: EMBL:U40275 xref: EMBL:U40276 xref: EMBL:U40277 xref: EMBL:U40278 xref: EMBL:U40279 xref: HGNC:HGNC:6146 xref: UniGene:Hs.679163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050190 ! ITAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014787 name: ITGAL_human def: "Integrin alpha-L precursor gene" [UniProtKB:P20701] synonym: "CD11A" EXACT [UniProtKB:P20701] xref: EMBL:AC002310 xref: EMBL:BC008777 xref: EMBL:CH471192 xref: EMBL:DQ131904 xref: EMBL:M87662 xref: EMBL:M95609 xref: EMBL:Y00796 xref: EMBL:Z22804 xref: HGNC:HGNC:6148 xref: UniGene:Hs.174103 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050199 ! Q96HB1_HUMAN relationship: codes_for CCO:B0050202 ! ITAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014788 name: ITGAM_human def: "Integrin alpha-M precursor gene" [UniProtKB:P11215] synonym: "CD11B" EXACT [UniProtKB:P11215] synonym: "CR3A" EXACT [UniProtKB:P11215] xref: EMBL:BC096347 xref: EMBL:BC096348 xref: EMBL:BC099660 xref: EMBL:J03925 xref: EMBL:J04145 xref: EMBL:M18044 xref: EMBL:M76724 xref: EMBL:M84477 xref: EMBL:S52152 xref: EMBL:S52153 xref: EMBL:S52154 xref: EMBL:S52155 xref: EMBL:S52157 xref: EMBL:S52159 xref: EMBL:S52161 xref: EMBL:S52164 xref: EMBL:S52165 xref: EMBL:S52167 xref: EMBL:S52169 xref: EMBL:S52170 xref: EMBL:S52173 xref: EMBL:S52174 xref: EMBL:S52180 xref: EMBL:S52181 xref: EMBL:S52184 xref: EMBL:S52189 xref: EMBL:S52191 xref: EMBL:S52192 xref: EMBL:S52203 xref: EMBL:S52212 xref: EMBL:S52213 xref: EMBL:S52216 xref: EMBL:S52219 xref: EMBL:S52220 xref: EMBL:S52221 xref: EMBL:S52222 xref: EMBL:S52226 xref: EMBL:S52227 xref: HGNC:HGNC:6149 xref: UniGene:Hs.172631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050188 ! Q4VAK1_HUMAN relationship: codes_for CCO:B0050189 ! ITAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014789 name: ITGAX_human def: "Integrin alpha-X precursor gene" [UniProtKB:P20702] synonym: "CD11C" EXACT [UniProtKB:P20702] xref: EMBL:BC038237 xref: EMBL:M29165 xref: EMBL:M29482 xref: EMBL:M29483 xref: EMBL:M29484 xref: EMBL:M29485 xref: EMBL:M29486 xref: EMBL:M29487 xref: EMBL:M81695 xref: HGNC:HGNC:6152 xref: UniGene:Hs.248472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050192 ! ITAX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014795 name: KCNQ1_human def: "Potassium voltage-gated channel subfamily KQT member 1 gene" [UniProtKB:P51787] synonym: "KCNA8" EXACT [UniProtKB:P51787] synonym: "KCNA9" EXACT [UniProtKB:P51787] synonym: "KVLQT1" EXACT [UniProtKB:P51787] xref: EMBL:AB015163 xref: EMBL:AF000571 xref: EMBL:AF051426 xref: EMBL:AJ006345 xref: EMBL:AY114213 xref: EMBL:U86146 xref: EMBL:U89364 xref: HGNC:HGNC:6294 xref: UniGene:Hs.95162 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049421 ! KCNQ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014816 name: MAP2_human def: "Microtubule-associated protein 2 gene" [UniProtKB:P11137] xref: EMBL:AC006385 xref: EMBL:AC019106 xref: EMBL:AC079833 xref: EMBL:AC108072 xref: EMBL:BC038857 xref: EMBL:BC110423 xref: EMBL:BC117123 xref: EMBL:CH471063 xref: EMBL:M25668 xref: EMBL:U01828 xref: EMBL:U89329 xref: EMBL:U89330 xref: HGNC:HGNC:6839 xref: UniGene:Hs.368281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050955 ! MAP2_HUMAN relationship: codes_for CCO:B0056188 ! Q17S04_HUMAN relationship: codes_for CCO:B0057329 ! Q8IUX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014825 name: MFN2_human def: "Mitofusin-2 gene" [UniProtKB:O95140] synonym: "CPRP1" EXACT [UniProtKB:O95140] synonym: "KIAA0214" EXACT [UniProtKB:O95140] xref: EMBL:AF036536 xref: EMBL:AL096840 xref: EMBL:AL137666 xref: EMBL:AY028429 xref: EMBL:BC017061 xref: EMBL:D86987 xref: HGNC:HGNC:16877 xref: UniGene:Hs.695980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050997 ! MFN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014831 name: MLL2_human def: "Histone-lysine N-methyltransferase MLL2 gene" [UniProtKB:O14686] synonym: "ALR" EXACT [UniProtKB:O14686] synonym: "KMT2B" EXACT [UniProtKB:O14686] xref: EMBL:AF010403 xref: EMBL:AF010404 xref: HGNC:HGNC:7133 xref: UniGene:Hs.120228 xref: UniGene:Hs.655939 xref: UniGene:Hs.675711 xref: UniGene:Hs.679013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050359 ! MLL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014832 name: MLL3_human def: "Histone-lysine N-methyltransferase MLL3 gene" [UniProtKB:Q8NEZ4] synonym: "HALR" EXACT [UniProtKB:Q8NEZ4] synonym: "KIAA1506" EXACT [UniProtKB:Q8NEZ4] synonym: "KMT2C" EXACT [UniProtKB:Q8NEZ4] xref: EMBL:AB040939 xref: EMBL:AC005631 xref: EMBL:AC006017 xref: EMBL:AC006474 xref: EMBL:AC104692 xref: EMBL:AF264750 xref: EMBL:AK022687 xref: EMBL:AK075113 xref: EMBL:AL833924 xref: EMBL:AY024361 xref: HGNC:HGNC:13726 xref: UniGene:Hs.647120 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050358 ! MLL3_HUMAN relationship: codes_for CCO:B0057102 ! Q75MN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014836 name: SLC16A8_human def: "Monocarboxylate transporter 3 gene" [UniProtKB:O95907] synonym: "MCT3" EXACT [UniProtKB:O95907] xref: EMBL:AF132610 xref: EMBL:AF132611 xref: EMBL:AL031587 xref: HGNC:HGNC:16270 xref: UniGene:Hs.270285 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051475 ! MOT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014840 name: MAP2K5_human def: "Dual specificity mitogen-activated protein kinase kinase 5 gene" [UniProtKB:Q13163] synonym: "MEK5" EXACT [UniProtKB:Q13163] synonym: "MKK5" EXACT [UniProtKB:Q13163] synonym: "PRKMK5" EXACT [UniProtKB:Q13163] xref: EMBL:BC008838 xref: EMBL:BT006780 xref: EMBL:CR542229 xref: EMBL:U25265 xref: EMBL:U71087 xref: EMBL:U71088 xref: HGNC:HGNC:6845 xref: UniGene:Hs.114198 xref: UniGene:Hs.646519 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050242 ! MP2K5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014845 name: NCKAP1_human def: "Nck-associated protein 1 gene" [UniProtKB:Q9Y2A7] synonym: "HEM2" EXACT [UniProtKB:Q9Y2A7] synonym: "KIAA0587" EXACT [UniProtKB:Q9Y2A7] synonym: "NAP1" EXACT [UniProtKB:Q9Y2A7] xref: EMBL:AB011159 xref: EMBL:AB014509 xref: EMBL:BC015025 xref: HGNC:HGNC:7666 xref: UniGene:Hs.603732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050612 ! NCKP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014849 name: TACR1_human def: "Substance-P receptor gene" [UniProtKB:P25103] synonym: "NK1R" EXACT [UniProtKB:P25103] synonym: "TAC1R" EXACT [UniProtKB:P25103] xref: EMBL:AC007681 xref: EMBL:AY462098 xref: EMBL:BC074911 xref: EMBL:BC074912 xref: EMBL:M74290 xref: EMBL:M76675 xref: EMBL:M81797 xref: EMBL:M84425 xref: EMBL:M84426 xref: EMBL:S62045 xref: EMBL:X65177 xref: EMBL:X65178 xref: EMBL:X65179 xref: EMBL:X65180 xref: EMBL:X65181 xref: HGNC:HGNC:11526 xref: UniGene:Hs.654419 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049448 ! Q53TQ2_HUMAN relationship: codes_for CCO:B0049457 ! NK1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014850 name: TACR2_human def: "Substance-K receptor gene" [UniProtKB:P21452] synonym: "NK2R" EXACT [UniProtKB:P21452] synonym: "NKNAR" EXACT [UniProtKB:P21452] synonym: "TAC2R" EXACT [UniProtKB:P21452] xref: EMBL:AC016821 xref: EMBL:AY322545 xref: EMBL:M57414 xref: EMBL:M57415 xref: EMBL:M60281 xref: EMBL:M60282 xref: EMBL:M60283 xref: EMBL:M60284 xref: EMBL:M75101 xref: EMBL:M75102 xref: EMBL:M75103 xref: EMBL:M75104 xref: EMBL:M75105 xref: HGNC:HGNC:11527 xref: UniGene:Hs.88372 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049445 ! A6NEW7_HUMAN relationship: codes_for CCO:B0049452 ! NK2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014851 name: TACR3_human def: "Neuromedin-K receptor gene" [UniProtKB:P29371] synonym: "NK3R" EXACT [UniProtKB:P29371] synonym: "TAC3R" EXACT [UniProtKB:P29371] xref: EMBL:AY462099 xref: EMBL:BC121806 xref: EMBL:M89473 xref: EMBL:S86371 xref: EMBL:S86382 xref: EMBL:S86388 xref: EMBL:S86390 xref: EMBL:S86392 xref: EMBL:X65172 xref: EMBL:X65173 xref: EMBL:X65174 xref: EMBL:X65175 xref: EMBL:X65176 xref: HGNC:HGNC:11528 xref: UniGene:Hs.942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049455 ! NK3R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014852 name: NLE1_human def: "Notchless protein homolog 1 gene" [UniProtKB:Q9NVX2] synonym: "HUSSY-07" EXACT [UniProtKB:Q9NVX2] xref: EMBL:AJ005257 xref: EMBL:AK001320 xref: EMBL:BC002884 xref: EMBL:BC012075 xref: HGNC:HGNC:19889 xref: UniGene:Hs.85570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050490 ! NLE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014855 name: NOV_human def: "Protein NOV homolog precursor gene" [UniProtKB:P48745] synonym: "CCN3" EXACT [UniProtKB:P48745] synonym: "IGFBP9" EXACT [UniProtKB:P48745] synonym: "NOVH" EXACT [UniProtKB:P48745] xref: EMBL:AY082381 xref: EMBL:BC015028 xref: EMBL:X78351 xref: EMBL:X78352 xref: EMBL:X78353 xref: EMBL:X78354 xref: EMBL:X96584 xref: HGNC:HGNC:7885 xref: UniGene:Hs.235935 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021697 ! NOV_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014856 name: NPBWR1_human def: "Neuropeptides B/W receptor type 1 gene" [UniProtKB:P48145] synonym: "GPR7" EXACT [UniProtKB:P48145] xref: EMBL:BC069117 xref: EMBL:BC107101 xref: EMBL:CH471068 xref: EMBL:U22491 xref: HGNC:HGNC:4522 xref: UniGene:Hs.248117 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050782 ! NPBW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014857 name: NPBWR2_human def: "Neuropeptides B/W receptor type 2 gene" [UniProtKB:P48146] synonym: "GPR8" EXACT [UniProtKB:P48146] xref: EMBL:AL121581 xref: EMBL:U22492 xref: HGNC:HGNC:4530 xref: UniGene:Hs.248118 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050764 ! NPBW2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014858 name: NRG1_human def: "Pro-neuregulin-1, membrane-bound isoform precursor gene" [UniProtKB:Q02297] synonym: "GGF" EXACT [UniProtKB:Q02297] synonym: "HGL" EXACT [UniProtKB:Q02297] synonym: "HRGA" EXACT [UniProtKB:Q02297] synonym: "NDF" EXACT [UniProtKB:Q02297] synonym: "SMDF" EXACT [UniProtKB:Q02297] xref: EMBL:AF009227 xref: EMBL:AF026146 xref: EMBL:AF491780 xref: EMBL:BC073871 xref: EMBL:BK000383 xref: EMBL:L12260 xref: EMBL:L12261 xref: EMBL:M94165 xref: EMBL:M94166 xref: EMBL:M94167 xref: EMBL:M94168 xref: EMBL:U02325 xref: EMBL:U02326 xref: EMBL:U02327 xref: EMBL:U02328 xref: EMBL:U02329 xref: EMBL:U02330 xref: HGNC:HGNC:7997 xref: UniGene:Hs.453951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049576 ! NRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014859 name: NOTCH2NL_human def: "Notch homolog 2 N-terminal-like protein gene" [UniProtKB:Q7Z3S9] synonym: "N2N" EXACT [UniProtKB:Q7Z3S9] xref: EMBL:AK075065 xref: EMBL:AL592307 xref: EMBL:BC010154 xref: EMBL:BC019835 xref: EMBL:BC065219 xref: EMBL:BC084572 xref: EMBL:BC090943 xref: EMBL:BX537434 xref: HGNC:HGNC:31862 xref: UniGene:Hs.515947 xref: UniGene:Hs.655156 xref: UniGene:Hs.683989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050820 ! NT2NL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014863 name: OR5AC1_human def: "Olfactory receptor 5AC1 gene" [UniProtKB:P0C628] synonym: "OR5AC1P" EXACT [UniProtKB:P0C628] xref: EMBL:AB065456 xref: EMBL:BK004740 xref: HGNC:HGNC:15047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0033347 ! O5AC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014864 name: OR5AK2_human def: "Olfactory receptor 5AK2 gene" [UniProtKB:Q8NH90] xref: EMBL:AB065496 xref: HGNC:HGNC:15251 xref: UniGene:Hs.554520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051887 ! O5AK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014865 name: OR5AP2_human def: "Olfactory receptor 5AP2 gene" [UniProtKB:Q8NGF4] xref: EMBL:AB065854 xref: HGNC:HGNC:15258 xref: UniGene:Hs.449692 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051893 ! O5AP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014866 name: OR5AR1_human def: "Olfactory receptor 5AR1 gene" [UniProtKB:Q8NGP9] xref: EMBL:AB065740 xref: EMBL:BK004401 xref: HGNC:HGNC:15260 xref: UniGene:Hs.553633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029035 ! O5AR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014867 name: OR5AS1_human def: "Olfactory receptor 5AS1 gene" [UniProtKB:Q8N127] xref: EMBL:AB065452 xref: EMBL:AB065543 xref: EMBL:BK004344 xref: HGNC:HGNC:15261 xref: UniGene:Hs.553625 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029038 ! O5AS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014871 name: ONECUT2_human def: "One cut domain family member 2 gene" [UniProtKB:O95948] synonym: "HNF6B" EXACT [UniProtKB:O95948] xref: EMBL:Y18198 xref: HGNC:HGNC:8139 xref: UniGene:Hs.194725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049070 ! ONEC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014872 name: ONECUT3_human def: "One cut domain family member 3 gene" [UniProtKB:O60422] xref: EMBL:AC004755 xref: EMBL:AC005256 xref: HGNC:HGNC:13399 xref: UniGene:Hs.654347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049069 ! ONEC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014874 name: OPRD1_human def: "Delta-type opioid receptor gene" [UniProtKB:P41143] synonym: "OPRD" EXACT [UniProtKB:P41143] xref: EMBL:AL009181 xref: EMBL:U07882 xref: EMBL:U10504 xref: HGNC:HGNC:8153 xref: UniGene:Hs.372 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050753 ! OPRD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014875 name: OPRK1_human def: "Kappa-type opioid receptor gene" [UniProtKB:P41145] synonym: "OPRK" EXACT [UniProtKB:P41145] xref: EMBL:AF498922 xref: EMBL:BC099912 xref: EMBL:L36130 xref: EMBL:L37362 xref: EMBL:U11053 xref: EMBL:U16860 xref: EMBL:U17298 xref: HGNC:HGNC:8154 xref: UniGene:Hs.106795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050758 ! OPRK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014876 name: OPRM1_human def: "Opioid receptor, mu 1 (Opioid receptor, mu 1, isoform CRA_b) gene" [UniProtKB:Q5TBX0] synonym: "hCG_32335" EXACT [UniProtKB:Q5TBX0] synonym: "RP3-402L9.1-001" EXACT [UniProtKB:Q5TBX0] xref: EMBL:AL132774 xref: EMBL:AL136444 xref: EMBL:CH471051 xref: HGNC:HGNC:8156 xref: UniGene:Hs.2353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050756 ! Q9H573_HUMAN relationship: codes_for CCO:B0050791 ! Q5TBX0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014877 name: OPRL1_human def: "Nociceptin receptor gene" [UniProtKB:P41146] synonym: "OOR" EXACT [UniProtKB:P41146] synonym: "ORL1" EXACT [UniProtKB:P41146] xref: EMBL:AF126470 xref: EMBL:AF348323 xref: EMBL:AL121581 xref: EMBL:AL590548 xref: EMBL:AY268428 xref: EMBL:BC038433 xref: EMBL:L40949 xref: EMBL:U30185 xref: EMBL:X77130 xref: HGNC:HGNC:8155 xref: UniGene:Hs.2859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050760 ! A6NL10_HUMAN relationship: codes_for CCO:B0050781 ! OPRX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014878 name: OR5B2_human def: "Olfactory receptor 5B2 gene" [UniProtKB:Q96R09] xref: EMBL:AB065852 xref: EMBL:AF399636 xref: EMBL:BK004505 xref: HGNC:HGNC:8323 xref: UniGene:Hs.553753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029024 ! OR5B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014879 name: OR5B3_human def: "Olfactory receptor 5B3 gene" [UniProtKB:Q8NH48] synonym: "OR5B13" EXACT [UniProtKB:Q8NH48] xref: EMBL:AB065545 xref: EMBL:BK004506 xref: HGNC:HGNC:8324 xref: UniGene:Hs.553826 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029017 ! OR5B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014880 name: OR5B12_human def: "Olfactory receptor 5B12 gene" [UniProtKB:Q96R08] synonym: "OR5B12P" EXACT [UniProtKB:Q96R08] synonym: "OR5B16" EXACT [UniProtKB:Q96R08] xref: EMBL:AB065851 xref: EMBL:AF399637 xref: EMBL:BK004507 xref: HGNC:HGNC:15432 xref: UniGene:Hs.553754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029028 ! OR5BC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014881 name: OR5B17_human def: "Olfactory receptor 5B17 gene" [UniProtKB:Q8NGF7] synonym: "OR5B20P" EXACT [UniProtKB:Q8NGF7] xref: EMBL:AB065849 xref: EMBL:BK004491 xref: HGNC:HGNC:15267 xref: UniGene:Hs.554517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029039 ! OR5BH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014882 name: OR5L1_human def: "Olfactory receptor 5L1 gene" [UniProtKB:Q8NGL2] xref: EMBL:AB065780 xref: EMBL:BC109249 xref: EMBL:BC109250 xref: EMBL:BK004332 xref: HGNC:HGNC:8350 xref: UniGene:Hs.553623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029023 ! OR5L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014883 name: OR5L2_human def: "Olfactory receptor 5L2 gene" [UniProtKB:Q8NGL0] xref: EMBL:AB065782 xref: EMBL:AF399526 xref: EMBL:BK004396 xref: EMBL:X64990 xref: HGNC:HGNC:8351 xref: UniGene:Hs.528356 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029040 ! OR5L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014884 name: OR5M11_human def: "Olfactory receptor 5M11 gene" [UniProtKB:Q96RB7] xref: EMBL:AF399521 xref: HGNC:HGNC:15291 xref: UniGene:Hs.553632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049817 ! OR5MB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014885 name: OR5R1_human def: "Olfactory receptor 5R1 gene" [UniProtKB:Q8NH85] synonym: "OR5R1P" EXACT [UniProtKB:Q8NH85] xref: EMBL:AB065504 xref: EMBL:BK004514 xref: HGNC:HGNC:14841 xref: UniGene:Hs.553630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029029 ! OR5R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014886 name: OR5W2_human def: "Olfactory receptor 5W2 gene" [UniProtKB:Q8NH69] synonym: "OR5W2P" EXACT [UniProtKB:Q8NH69] synonym: "OR5W3P" EXACT [UniProtKB:Q8NH69] xref: EMBL:AB065520 xref: EMBL:BK004398 xref: HGNC:HGNC:15299 xref: UniGene:Hs.554526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029015 ! OR5W2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014887 name: OR8B4_human def: "Olfactory receptor 8B4 gene" [UniProtKB:Q96RC9] synonym: "OR8B4P" EXACT [UniProtKB:Q96RC9] xref: EMBL:AB065831 xref: EMBL:AF399509 xref: HGNC:HGNC:8473 xref: UniGene:Hs.553671 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049813 ! OR8B4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014888 name: OR8D2_human def: "Olfactory receptor 8D2 gene" [UniProtKB:Q9GZM6] xref: EMBL:AF162668 xref: EMBL:AF162669 xref: HGNC:HGNC:8482 xref: UniGene:Hs.504212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051877 ! OR8D2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014889 name: OR8D4_human def: "Olfactory receptor 8D4 gene" [UniProtKB:Q8NGM9] xref: EMBL:AB065761 xref: HGNC:HGNC:14840 xref: UniGene:Hs.449688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029034 ! OR8D4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014890 name: OR8G1_human def: "Olfactory receptor 8G1 gene" [UniProtKB:Q15617] synonym: "OR8G1P" EXACT [UniProtKB:Q15617] xref: EMBL:AB065946 xref: EMBL:AF399507 xref: EMBL:BK004423 xref: EMBL:X89672 xref: HGNC:HGNC:8484 xref: UniGene:Hs.448172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051880 ! OR8G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014891 name: OR8G2_human def: "Olfactory receptor 8G2 gene" [UniProtKB:Q15614] synonym: "OR8G2P" EXACT [UniProtKB:Q15614] synonym: "OR8G4" EXACT [UniProtKB:Q15614] xref: EMBL:BC136638 xref: EMBL:BK004424 xref: EMBL:BK004426 xref: EMBL:X89669 xref: HGNC:HGNC:8485 xref: UniGene:Hs.381319 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051882 ! OR8G2_HUMAN relationship: codes_for CCO:B0056776 ! Q6IF36_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014892 name: OR8G5_human def: "Olfactory receptor 8G5 gene" [UniProtKB:Q8NG78] synonym: "OR8G5P" EXACT [UniProtKB:Q8NG78] synonym: "OR8G6" EXACT [UniProtKB:Q8NG78] xref: EMBL:AB065958 xref: EMBL:BK004516 xref: HGNC:HGNC:19622 xref: UniGene:Hs.626840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029031 ! OR8G5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014893 name: OR8H1_human def: "Olfactory receptor 8H1 gene" [UniProtKB:Q8NGG4] xref: EMBL:AB065836 xref: EMBL:AC022882 xref: EMBL:BK004337 xref: HGNC:HGNC:14824 xref: UniGene:Hs.553628 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049806 ! OR8H1_HUMAN relationship: codes_for CCO:B0049812 ! A8MYM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014894 name: OR8H2_human def: "Olfactory receptor 8H2 gene" [UniProtKB:Q8N162] xref: EMBL:AB065657 xref: EMBL:AB065845 xref: EMBL:BK004341 xref: HGNC:HGNC:15308 xref: UniGene:Hs.553744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049816 ! OR8H2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014895 name: OR8H3_human def: "Olfactory receptor 8H3 gene" [UniProtKB:Q8N146] xref: EMBL:AB065658 xref: EMBL:AB065840 xref: EMBL:AC068339 xref: EMBL:BK004345 xref: HGNC:HGNC:15309 xref: UniGene:Hs.553745 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049809 ! A8MYY4_HUMAN relationship: codes_for CCO:B0049814 ! OR8H3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014896 name: OR8K5_human def: "Olfactory receptor 8K5 gene" [UniProtKB:Q8NH50] xref: EMBL:AB065542 xref: EMBL:AP003034 xref: HGNC:HGNC:15315 xref: UniGene:Hs.553626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029022 ! OR8K5_HUMAN relationship: codes_for CCO:B0029037 ! A8MXK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014897 name: OR8U1_human def: "Olfactory receptor 8U1 gene" [UniProtKB:Q8NH10] xref: EMBL:AB065603 xref: HGNC:HGNC:19611 xref: UniGene:Hs.553618 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029025 ! OR8U1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014898 name: OR8U8_human def: "Olfactory receptor 8U8 gene" [UniProtKB:P0C7N1] xref: EMBL:CH471076 xref: HGNC:HGNC:27538 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051892 ! OR8U8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014899 name: OR8U9_human def: "Olfactory receptor 8U9 gene" [UniProtKB:P0C7N5] xref: EMBL:CH471076 xref: HGNC:HGNC:29166 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051883 ! OR8U9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014900 name: OR9G4_human def: "Putative uncharacterized protein OR9G4 gene" [UniProtKB:A8MUX1] xref: EMBL:AP001803 xref: HGNC:HGNC:15322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029027 ! A8MUX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014901 name: OR9I1_human def: "Olfactory receptor 9I1 gene" [UniProtKB:Q8NGQ6] xref: EMBL:AB065733 xref: EMBL:AF399531 xref: HGNC:HGNC:14718 xref: UniGene:Hs.632122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029013 ! OR9I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014905 name: P2RY8_human def: "P2Y purinoceptor 8 gene" [UniProtKB:Q86VZ1] xref: EMBL:AL683870 xref: EMBL:BC043610 xref: HGNC:HGNC:15524 xref: UniGene:Hs.111377 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016986 ! P2RY8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014907 name: PANK4_human def: "Pantothenate kinase 4 gene" [UniProtKB:Q9NVE7] xref: EMBL:AK001644 xref: EMBL:AK223546 xref: EMBL:AL139246 xref: EMBL:AL442072 xref: EMBL:BC043496 xref: EMBL:BK000012 xref: HGNC:HGNC:19366 xref: UniGene:Hs.26156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050004 ! PANK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014908 name: F2RL1_human def: "Proteinase-activated receptor 2 precursor gene" [UniProtKB:P55085] synonym: "GPR11" EXACT [UniProtKB:P55085] synonym: "PAR2" EXACT [UniProtKB:P55085] xref: EMBL:AF400075 xref: EMBL:BC012453 xref: EMBL:BC018130 xref: EMBL:U34038 xref: EMBL:U36753 xref: EMBL:Z49993 xref: EMBL:Z49994 xref: HGNC:HGNC:3538 xref: UniGene:Hs.154299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049161 ! PAR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014910 name: F2RL3_human def: "Proteinase-activated receptor 4 precursor gene" [UniProtKB:Q96RI0] synonym: "PAR4" EXACT [UniProtKB:Q96RI0] xref: EMBL:AF055917 xref: EMBL:AF080214 xref: EMBL:AF384819 xref: EMBL:AY431102 xref: EMBL:BC074782 xref: HGNC:HGNC:3540 xref: UniGene:Hs.137574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049157 ! PAR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014911 name: PDLIM4_human def: "PDZ and LIM domain protein 4 gene" [UniProtKB:P50479] synonym: "RIL" EXACT [UniProtKB:P50479] xref: EMBL:AF153882 xref: EMBL:AF154335 xref: EMBL:BC003096 xref: EMBL:BC016765 xref: EMBL:U82997 xref: EMBL:X93510 xref: HGNC:HGNC:16501 xref: UniGene:Hs.424312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017106 ! PDLI4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014915 name: PGRMC1_human def: "Membrane-associated progesterone receptor component 1 gene" [UniProtKB:O00264] synonym: "HPR6.6" EXACT [UniProtKB:O00264] synonym: "PGRMC" EXACT [UniProtKB:O00264] xref: EMBL:AJ249131 xref: EMBL:BC034238 xref: EMBL:Y12711 xref: HGNC:HGNC:16090 xref: UniGene:Hs.90061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051023 ! PGRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014925 name: POU1F1_human def: "Pituitary-specific positive transcription factor 1 gene" [UniProtKB:P28069] synonym: "GHF1" EXACT [UniProtKB:P28069] synonym: "PIT1" EXACT [UniProtKB:P28069] xref: EMBL:D10216 xref: EMBL:D11333 xref: EMBL:D12892 xref: EMBL:L18781 xref: EMBL:X62429 xref: EMBL:X72215 xref: EMBL:X77223 xref: EMBL:X77224 xref: HGNC:HGNC:9210 xref: UniGene:Hs.591654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048652 ! PIT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014927 name: PLAG1_human def: "Zinc finger protein PLAG1 gene" [UniProtKB:Q6DJT9] xref: EMBL:AB209131 xref: EMBL:BC075047 xref: EMBL:BC075048 xref: EMBL:U65002 xref: HGNC:HGNC:9045 xref: UniGene:Hs.14968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016794 ! PLAG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014928 name: PLAGL2_human def: "Zinc finger protein PLAGL2 gene" [UniProtKB:Q9UPG8] synonym: "KIAA0198" EXACT [UniProtKB:Q9UPG8] xref: EMBL:AF006005 xref: EMBL:AL121897 xref: EMBL:BC023655 xref: EMBL:D83784 xref: HGNC:HGNC:9047 xref: UniGene:Hs.154104 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016798 ! PLAL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014929 name: PLEC1_human def: "Plectin-1 gene" [UniProtKB:Q15149] xref: EMBL:AY480047 xref: EMBL:AY480051 xref: EMBL:U53204 xref: EMBL:U63609 xref: EMBL:U63610 xref: EMBL:X97053 xref: EMBL:Z54367 xref: HGNC:HGNC:9069 xref: UniGene:Hs.434248 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050497 ! PLEC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014930 name: POU3F1_human def: "POU class 3 homeobox 1 (POU domain, class 3, transcription factor 1) gene" [UniProtKB:Q5TAG2] synonym: "hCG_1641045" EXACT [UniProtKB:Q5TAG2] synonym: "RP5-884C9.1-001" EXACT [UniProtKB:Q5TAG2] xref: EMBL:AL139158 xref: EMBL:CH471059 xref: HGNC:HGNC:9214 xref: UniGene:Hs.1837 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048659 ! Q5TAG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014931 name: POU3F2_human def: "POU domain, class 3, transcription factor 2 gene" [UniProtKB:P20265] synonym: "BRN2" EXACT [UniProtKB:P20265] synonym: "OCT7" EXACT [UniProtKB:P20265] synonym: "OTF7" EXACT [UniProtKB:P20265] xref: EMBL:AL022395 xref: EMBL:BC051699 xref: EMBL:L37868 xref: EMBL:Z11933 xref: HGNC:HGNC:9215 xref: UniGene:Hs.182505 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048655 ! PO3F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014932 name: POU3F4_human def: "POU domain, class 3, transcription factor 4 gene" [UniProtKB:P49335] synonym: "BRN4" EXACT [UniProtKB:P49335] synonym: "OTF9" EXACT [UniProtKB:P49335] xref: EMBL:X82324 xref: EMBL:Z82170 xref: HGNC:HGNC:9217 xref: UniGene:Hs.2229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048661 ! PO3F4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014933 name: POU4F1_human def: "POU domain, class 4, transcription factor 1 gene" [UniProtKB:Q01851] synonym: "BRN3A" EXACT [UniProtKB:Q01851] synonym: "RDC1" EXACT [UniProtKB:Q01851] xref: EMBL:AL445209 xref: EMBL:CH471093 xref: EMBL:L20433 xref: EMBL:U10062 xref: EMBL:U10063 xref: EMBL:X64624 xref: HGNC:HGNC:9218 xref: UniGene:Hs.654522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048650 ! PO4F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014934 name: POU4F3_human def: "POU domain, class 4, transcription factor 3 gene" [UniProtKB:Q15319] synonym: "BRN3C" EXACT [UniProtKB:Q15319] xref: EMBL:AF044575 xref: EMBL:BC104923 xref: EMBL:BC112207 xref: EMBL:U10060 xref: EMBL:U10061 xref: HGNC:HGNC:9220 xref: UniGene:Hs.553499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048651 ! PO4F3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014935 name: POU5F1_human def: "POU domain, class 5, transcription factor 1 gene" [UniProtKB:Q01860] synonym: "OCT3" EXACT [UniProtKB:Q01860] synonym: "OCT4" EXACT [UniProtKB:Q01860] synonym: "OTF3" EXACT [UniProtKB:Q01860] xref: EMBL:AB088113 xref: EMBL:AB103619 xref: EMBL:AB202105 xref: EMBL:AL662833 xref: EMBL:AL662844 xref: EMBL:AL773544 xref: EMBL:BA000025 xref: EMBL:BC117435 xref: EMBL:BC117437 xref: EMBL:BX088580 xref: EMBL:CH471081 xref: EMBL:CR388229 xref: EMBL:CR759815 xref: EMBL:CR847794 xref: EMBL:DQ120688 xref: EMBL:DQ486513 xref: EMBL:S81255 xref: EMBL:Z11898 xref: EMBL:Z11899 xref: EMBL:Z21963 xref: EMBL:Z21964 xref: HGNC:HGNC:9221 xref: HGNC:HGNC:9223 xref: UniGene:Hs.249184 xref: UniGene:Hs.450254 xref: UniGene:Hs.594817 xref: UniGene:Hs.632482 xref: UniGene:Hs.646545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048656 ! PO5F1_HUMAN relationship: codes_for CCO:B0048672 ! Q2VIK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014936 name: POU5F2_human def: "POU domain, class 5, transcription factor 2 gene" [UniProtKB:Q8N7G0] synonym: "SPRM1" EXACT [UniProtKB:Q8N7G0] xref: EMBL:AK098546 xref: EMBL:BC029532 xref: EMBL:BX641019 xref: EMBL:Z21965 xref: HGNC:HGNC:26367 xref: UniGene:Hs.678995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048662 ! PO5F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014937 name: POU5F1P1_human def: "Putative POU domain, class 5, transcription factor 1-like protein 1 gene" [UniProtKB:Q06416] synonym: "OTF3C" EXACT [UniProtKB:Q06416] synonym: "OTF3P1" EXACT [UniProtKB:Q06416] synonym: "POU5FLC20" EXACT [UniProtKB:Q06416] synonym: "POU5FLC8" EXACT [UniProtKB:Q06416] xref: EMBL:AC016883 xref: EMBL:AF268615 xref: EMBL:AF268618 xref: EMBL:Z11901 xref: HGNC:HGNC:9223 xref: UniGene:Hs.450254 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048653 ! PO5L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014938 name: PPT1_human def: "Palmitoyl-protein thioesterase 1 precursor gene" [UniProtKB:P50897] synonym: "PPT" EXACT [UniProtKB:P50897] xref: EMBL:AF022203 xref: EMBL:AF022204 xref: EMBL:AF022205 xref: EMBL:AF022206 xref: EMBL:AF022207 xref: EMBL:AF022208 xref: EMBL:AF022209 xref: EMBL:AF022210 xref: EMBL:AF022211 xref: EMBL:BC008426 xref: EMBL:L42809 xref: EMBL:U44772 xref: HGNC:HGNC:9325 xref: UniGene:Hs.3873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049794 ! PPT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014970 name: CTPS2_human def: "CTP synthase 2 gene" [UniProtKB:Q9NRF8] xref: EMBL:AC073909 xref: EMBL:AF226667 xref: EMBL:AK023549 xref: EMBL:AK024070 xref: EMBL:AL445467 xref: EMBL:BC006256 xref: EMBL:BC034986 xref: HGNC:HGNC:2520 xref: UniGene:Hs.227049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049297 ! PYRG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014972 name: RAMP3_human def: "Receptor activity-modifying protein 3 precursor gene" [UniProtKB:O60896] xref: EMBL:AC004844 xref: EMBL:AJ001016 xref: EMBL:AY265459 xref: EMBL:BC022304 xref: HGNC:HGNC:9845 xref: UniGene:Hs.25691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049915 ! RAMP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014976 name: RICTOR_human def: "Rapamycin-insensitive companion of mTOR gene" [UniProtKB:Q6R327] synonym: "KIAA1999" EXACT [UniProtKB:Q6R327] xref: EMBL:AB082530 xref: EMBL:AL834497 xref: EMBL:AY515854 xref: EMBL:BC051729 xref: EMBL:CH471119 xref: EMBL:CR749280 xref: UniGene:Hs.407926 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048930 ! RICTR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014977 name: RIOK3_human def: "Serine/threonine-protein kinase RIO3 gene" [UniProtKB:O14730] synonym: "SUDD" EXACT [UniProtKB:O14730] xref: EMBL:AC026634 xref: EMBL:AF013591 xref: EMBL:BC039729 xref: HGNC:HGNC:11451 xref: UniGene:Hs.445511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051572 ! RIOK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014981 name: RNF4_human def: "RING finger protein 4 gene" [UniProtKB:P78317] synonym: "RES4-26" EXACT [UniProtKB:P78317] xref: EMBL:AB000468 xref: EMBL:BC031935 xref: EMBL:U95140 xref: HGNC:HGNC:10067 xref: UniGene:Hs.66394 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049848 ! RNF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014982 name: HNRNPA0_human def: "Heterogeneous nuclear ribonucleoprotein A0 gene" [UniProtKB:Q13151] synonym: "HNRPA0" EXACT [UniProtKB:Q13151] xref: EMBL:BC001008 xref: EMBL:BC007271 xref: EMBL:BC009284 xref: EMBL:BC011972 xref: EMBL:BC012980 xref: EMBL:BC018949 xref: EMBL:BC019271 xref: EMBL:BC028976 xref: EMBL:BC030249 xref: EMBL:U23803 xref: HGNC:HGNC:5030 xref: UniGene:Hs.645902 xref: UniGene:Hs.96996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028238 ! ROA0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014984 name: HNRNPA3_human def: "Heterogeneous nuclear ribonucleoprotein A3 gene" [UniProtKB:P51991] synonym: "HNRPA3" EXACT [UniProtKB:P51991] xref: EMBL:AC079305 xref: EMBL:AY363225 xref: EMBL:BC112027 xref: EMBL:BC113470 xref: HGNC:HGNC:24941 xref: UniGene:Hs.516539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028239 ! ROA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014985 name: ROS1_human def: "Proto-oncogene tyrosine-protein kinase ROS precursor gene" [UniProtKB:P08922] xref: EMBL:AL132671 xref: EMBL:M13368 xref: EMBL:M13591 xref: EMBL:M13592 xref: EMBL:M13593 xref: EMBL:M13594 xref: EMBL:M13595 xref: EMBL:M13596 xref: EMBL:M13597 xref: EMBL:M13598 xref: EMBL:M13599 xref: EMBL:M13880 xref: EMBL:M34353 xref: EMBL:Z98880 xref: HGNC:HGNC:10261 xref: UniGene:Hs.1041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029082 ! ROS_HUMAN relationship: codes_for CCO:B0049556 ! Q5H8Y1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014986 name: POLR1B_human def: "DNA-directed RNA polymerase I subunit RPA2 gene" [UniProtKB:Q9H9Y6] xref: EMBL:AC012442 xref: EMBL:AK022533 xref: EMBL:AK022890 xref: EMBL:AK128044 xref: EMBL:BC004882 xref: HGNC:HGNC:20454 xref: UniGene:Hs.86337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049472 ! Q9BSR4_HUMAN relationship: codes_for CCO:B0049473 ! RPA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014987 name: RTF1_human def: "RNA polymerase-associated protein RTF1 homolog gene" [UniProtKB:Q92541] synonym: "KIAA0252" EXACT [UniProtKB:Q92541] xref: EMBL:BC015052 xref: EMBL:D87440 xref: HGNC:HGNC:28996 xref: UniGene:Hs.511096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051565 ! RTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014989 name: RYR2_human def: "Ryanodine receptor 2 gene" [UniProtKB:Q92736] xref: EMBL:AJ002511 xref: EMBL:AJ300340 xref: EMBL:AJ300341 xref: EMBL:AJ300342 xref: EMBL:AJ300343 xref: EMBL:AJ300344 xref: EMBL:AJ300345 xref: EMBL:AJ300346 xref: EMBL:AJ300347 xref: EMBL:AJ300348 xref: EMBL:AJ300349 xref: EMBL:AJ300350 xref: EMBL:AJ300351 xref: EMBL:AJ300352 xref: EMBL:AJ300353 xref: EMBL:AJ300354 xref: EMBL:AJ300355 xref: EMBL:AJ300356 xref: EMBL:AJ300357 xref: EMBL:AJ300358 xref: EMBL:AJ300359 xref: EMBL:AJ300360 xref: EMBL:AJ300361 xref: EMBL:AJ300362 xref: EMBL:AJ300363 xref: EMBL:AJ300364 xref: EMBL:AJ300365 xref: EMBL:AJ300366 xref: EMBL:AJ300367 xref: EMBL:AJ300368 xref: EMBL:AJ300369 xref: EMBL:AJ300370 xref: EMBL:AJ300371 xref: EMBL:AJ300372 xref: EMBL:AJ300373 xref: EMBL:AJ300374 xref: EMBL:AJ300375 xref: EMBL:AJ300376 xref: EMBL:AJ300377 xref: EMBL:AJ300378 xref: EMBL:AJ300379 xref: EMBL:AJ300380 xref: EMBL:AJ300381 xref: EMBL:AJ300382 xref: EMBL:AJ300383 xref: EMBL:AJ300384 xref: EMBL:AJ300385 xref: EMBL:AJ300386 xref: EMBL:AJ300387 xref: EMBL:AJ300388 xref: EMBL:AJ300389 xref: EMBL:AJ300390 xref: EMBL:AJ300391 xref: EMBL:AJ300392 xref: EMBL:AJ300393 xref: EMBL:AJ300394 xref: EMBL:AJ300395 xref: EMBL:AJ300396 xref: EMBL:AJ300397 xref: EMBL:AJ300398 xref: EMBL:AJ300399 xref: EMBL:AJ300400 xref: EMBL:AJ300401 xref: EMBL:AJ300402 xref: EMBL:AJ300403 xref: EMBL:AJ300404 xref: EMBL:AJ300405 xref: EMBL:AJ300406 xref: EMBL:AJ300407 xref: EMBL:AJ300408 xref: EMBL:AJ300409 xref: EMBL:AJ300410 xref: EMBL:AJ300411 xref: EMBL:AJ300412 xref: EMBL:AJ300413 xref: EMBL:AJ300414 xref: EMBL:AJ300415 xref: EMBL:AJ300416 xref: EMBL:AJ300417 xref: EMBL:AJ300418 xref: EMBL:AJ300419 xref: EMBL:AJ300420 xref: EMBL:AJ300421 xref: EMBL:AJ300422 xref: EMBL:AJ300423 xref: EMBL:AJ300424 xref: EMBL:AJ300425 xref: EMBL:AJ300426 xref: EMBL:AJ300427 xref: EMBL:AJ300428 xref: EMBL:AJ300429 xref: EMBL:AJ300430 xref: EMBL:AJ300431 xref: EMBL:AJ300432 xref: EMBL:AJ300433 xref: EMBL:AJ300434 xref: EMBL:AJ300435 xref: EMBL:AJ300436 xref: EMBL:AJ300437 xref: EMBL:AJ300438 xref: EMBL:AJ300439 xref: EMBL:AJ300440 xref: EMBL:AJ300441 xref: EMBL:AJ300442 xref: EMBL:AJ300443 xref: EMBL:AJ300444 xref: EMBL:AL356773 xref: EMBL:AL359924 xref: EMBL:AL365332 xref: EMBL:AL391809 xref: EMBL:AL442065 xref: EMBL:AL445473 xref: EMBL:AL513130 xref: EMBL:X91869 xref: EMBL:X98330 xref: EMBL:Y08218 xref: HGNC:HGNC:10484 xref: UniGene:Hs.109514 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049439 ! RYR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014991 name: S100A7_human def: "Protein S100-A7 gene" [UniProtKB:P31151] synonym: "PSOR1" EXACT [UniProtKB:P31151] synonym: "S100A7C" EXACT [UniProtKB:P31151] xref: EMBL:AJ012825 xref: EMBL:AL591704 xref: EMBL:BC034687 xref: EMBL:BR000043 xref: EMBL:CR542164 xref: EMBL:M86757 xref: HGNC:HGNC:10497 xref: UniGene:Hs.112408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051700 ! S10A7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0014999 name: SCAND3_human def: "SCAN domain-containing protein 3 gene" [UniProtKB:Q6R2W3] synonym: "KIAA1925" EXACT [UniProtKB:Q6R2W3] synonym: "ZNF305P2" EXACT [UniProtKB:Q6R2W3] synonym: "ZNF452" EXACT [UniProtKB:Q6R2W3] xref: EMBL:AB067512 xref: EMBL:AK056369 xref: EMBL:AL671879 xref: EMBL:AL713690 xref: EMBL:AY517631 xref: EMBL:BC110834 xref: EMBL:BC111741 xref: EMBL:BC111742 xref: HGNC:HGNC:13851 xref: UniGene:Hs.176980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049841 ! SCND3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015002 name: SELI_human def: "SELI protein gene" [UniProtKB:Q8WU57] synonym: "hCG_1651316" EXACT [UniProtKB:Q8WU57] synonym: "tmp_locus_24" EXACT [UniProtKB:Q8WU57] xref: EMBL:AC010896 xref: EMBL:BC021229 xref: EMBL:CH471053 xref: UniGene:Hs.189073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051832 ! Q8WU57_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015003 name: SETD2_human def: "Histone-lysine N-methyltransferase SETD2 gene" [UniProtKB:Q9BYW2] synonym: "HIF1" EXACT [UniProtKB:Q9BYW2] synonym: "HSPC069" EXACT [UniProtKB:Q9BYW2] synonym: "HYPB" EXACT [UniProtKB:Q9BYW2] synonym: "KIAA1732" EXACT [UniProtKB:Q9BYW2] synonym: "KMT3A" EXACT [UniProtKB:Q9BYW2] synonym: "SET2" EXACT [UniProtKB:Q9BYW2] xref: EMBL:AB051519 xref: EMBL:AF049103 xref: EMBL:AF049610 xref: EMBL:AF161554 xref: EMBL:AJ238403 xref: EMBL:AK026125 xref: EMBL:AK127782 xref: EMBL:AK131371 xref: EMBL:AL713692 xref: EMBL:AL831959 xref: EMBL:AL833394 xref: EMBL:AY576987 xref: EMBL:AY576988 xref: EMBL:BC072440 xref: EMBL:BC090954 xref: EMBL:BC117162 xref: EMBL:BC117164 xref: HGNC:HGNC:18420 xref: UniGene:Hs.517941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014847 ! SETD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015005 name: SF3B1_human def: "Splicing factor 3B subunit 1 gene" [UniProtKB:O75533] synonym: "SAP155" EXACT [UniProtKB:O75533] xref: EMBL:AF054284 xref: EMBL:AF070540 xref: HGNC:HGNC:10768 xref: UniGene:Hs.632554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049991 ! SF3B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015006 name: SFRS3_human def: "Splicing factor, arginine/serine-rich 3 gene" [UniProtKB:P84103] synonym: "SRP20" EXACT [UniProtKB:P84103] xref: EMBL:AF107405 xref: EMBL:BC000914 xref: EMBL:BC069018 xref: EMBL:BT007017 xref: EMBL:L10838 xref: EMBL:Z85986 xref: HGNC:HGNC:10785 xref: UniGene:Hs.405144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050254 ! SFRS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015012 name: SNW1_human def: "SNW domain-containing protein 1 gene" [UniProtKB:Q13573] synonym: "SKIIP" EXACT [UniProtKB:Q13573] synonym: "SKIP" EXACT [UniProtKB:Q13573] xref: EMBL:AC008372 xref: EMBL:AF045184 xref: EMBL:BC040112 xref: EMBL:BC046105 xref: EMBL:BC108903 xref: EMBL:BT020060 xref: EMBL:BT020061 xref: EMBL:CR457433 xref: EMBL:U43960 xref: EMBL:U51432 xref: HGNC:HGNC:16696 xref: UniGene:Hs.546550 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048570 ! Q6I9S2_HUMAN relationship: codes_for CCO:B0048571 ! SNW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015013 name: SUPT4H1_human def: "Transcription elongation factor SPT4 gene" [UniProtKB:P63272] synonym: "SPT4H" EXACT [UniProtKB:P63272] synonym: "SUPT4H" EXACT [UniProtKB:P63272] xref: EMBL:AK129758 xref: EMBL:BC002802 xref: EMBL:CR407663 xref: EMBL:U38817 xref: EMBL:U38818 xref: EMBL:U43923 xref: HGNC:HGNC:11467 xref: UniGene:Hs.439481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051010 ! SPT4H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015017 name: SREBF1_human def: "Sterol regulatory element-binding protein 1 gene" [UniProtKB:P36956] synonym: "SREBP1" EXACT [UniProtKB:P36956] xref: EMBL:AB209609 xref: EMBL:BC023621 xref: EMBL:BC026962 xref: EMBL:BC057388 xref: EMBL:BC063281 xref: EMBL:CH471196 xref: EMBL:S66167 xref: EMBL:S66168 xref: EMBL:U00968 xref: HGNC:HGNC:11289 xref: UniGene:Hs.592123 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049929 ! SRBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015018 name: SREBF2_human def: "Sterol regulatory element-binding protein 2 gene" [UniProtKB:Q12772] synonym: "SREBP2" EXACT [UniProtKB:Q12772] xref: EMBL:AL021453 xref: EMBL:BC051385 xref: EMBL:BC051799 xref: EMBL:BC056158 xref: EMBL:CT841522 xref: EMBL:U02031 xref: EMBL:Z99716 xref: HGNC:HGNC:11290 xref: UniGene:Hs.443258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049933 ! Q05BD5_HUMAN relationship: codes_for CCO:B0049934 ! SRBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015019 name: SRP9_human def: "Signal recognition particle 9 kDa protein gene" [UniProtKB:P49458] xref: EMBL:BC008443 xref: EMBL:BC015094 xref: EMBL:BC022415 xref: EMBL:BC066957 xref: EMBL:BC067845 xref: EMBL:CH471098 xref: EMBL:EF488978 xref: EMBL:U20998 xref: HGNC:HGNC:11304 xref: UniGene:Hs.511425 xref: UniGene:Hs.620844 xref: UniGene:Hs.632087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051562 ! SRP09_HUMAN relationship: codes_for CCO:B0051564 ! Q6NVX0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015020 name: SSTR1_human def: "Somatostatin receptor type 1 gene" [UniProtKB:P30872] xref: EMBL:AY322536 xref: EMBL:BC035618 xref: EMBL:M81829 xref: HGNC:HGNC:11330 xref: UniGene:Hs.248160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050788 ! SSR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015021 name: SSTR2_human def: "Somatostatin receptor type 2 gene" [UniProtKB:P30874] xref: EMBL:AB065911 xref: EMBL:AF184174 xref: EMBL:AY236542 xref: EMBL:BC000256 xref: EMBL:BC009522 xref: EMBL:BC019610 xref: EMBL:BC095495 xref: EMBL:BT019926 xref: EMBL:M81830 xref: HGNC:HGNC:11331 xref: UniGene:Hs.514451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050755 ! SSR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015022 name: SSTR3_human def: "Somatostatin receptor type 3 gene" [UniProtKB:P32745] xref: EMBL:AY277678 xref: EMBL:AY322541 xref: EMBL:BC096829 xref: EMBL:CR456585 xref: EMBL:M96738 xref: EMBL:Z82188 xref: HGNC:HGNC:11332 xref: UniGene:Hs.225995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050794 ! SSR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015023 name: SSTR4_human def: "Somatostatin receptor type 4 gene" [UniProtKB:P31391] xref: EMBL:AL049651 xref: EMBL:AY548169 xref: EMBL:BC069063 xref: EMBL:BC117270 xref: EMBL:BC117272 xref: EMBL:CH471133 xref: EMBL:D16826 xref: EMBL:L07061 xref: EMBL:L07833 xref: EMBL:L14856 xref: HGNC:HGNC:11333 xref: UniGene:Hs.673846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050793 ! SSR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015024 name: SSTR5_human def: "Somatostatin receptor type 5 gene" [UniProtKB:P35346] xref: EMBL:AE006466 xref: EMBL:AL031713 xref: EMBL:D16827 xref: EMBL:L14865 xref: HGNC:HGNC:11334 xref: UniGene:Hs.449840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050785 ! SSR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015028 name: SYNJ2_human def: "Synaptojanin-2 gene" [UniProtKB:O15056] synonym: "KIAA0348" EXACT [UniProtKB:O15056] xref: EMBL:AB002346 xref: EMBL:AF039945 xref: EMBL:AF318616 xref: EMBL:AL139330 xref: EMBL:AY152396 xref: EMBL:BC043277 xref: HGNC:HGNC:11504 xref: UniGene:Hs.434494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051188 ! SYNJ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015029 name: GTF2A2_human def: "Transcription initiation factor IIA subunit 2 gene" [UniProtKB:P52657] synonym: "TF2A2" EXACT [UniProtKB:P52657] xref: EMBL:BC000287 xref: EMBL:BC001919 xref: EMBL:BT007362 xref: EMBL:CH471082 xref: EMBL:CR542192 xref: EMBL:U14193 xref: EMBL:U21242 xref: EMBL:X81713 xref: HGNC:HGNC:4647 xref: UniGene:Hs.512934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048483 ! T2AG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015031 name: SUB1_human def: "Activated RNA polymerase II transcriptional coactivator p15 gene" [UniProtKB:P53999] synonym: "PC4" EXACT [UniProtKB:P53999] synonym: "RPO2TC1" EXACT [UniProtKB:P53999] xref: EMBL:BC009610 xref: EMBL:BC010537 xref: EMBL:BC018189 xref: EMBL:BC022339 xref: EMBL:U12979 xref: EMBL:X79805 xref: HGNC:HGNC:19985 xref: UniGene:Hs.229641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048676 ! TCP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015032 name: TNC_human def: "Tenascin precursor gene" [UniProtKB:P24821] synonym: "HXB" EXACT [UniProtKB:P24821] xref: EMBL:BC151843 xref: EMBL:M24630 xref: EMBL:M55618 xref: EMBL:X56160 xref: EMBL:X78565 xref: EMBL:X80280 xref: HGNC:HGNC:5318 xref: UniGene:Hs.143250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050216 ! A7MBN2_HUMAN relationship: codes_for CCO:B0050218 ! TENA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015033 name: GTF2H4_human def: "General transcription factor IIH subunit 4 gene" [UniProtKB:Q92759] xref: EMBL:AL662854 xref: EMBL:AL669830 xref: EMBL:AY124590 xref: EMBL:BA000025 xref: EMBL:BC004935 xref: EMBL:BC016302 xref: EMBL:BT007321 xref: EMBL:BX927194 xref: EMBL:CR759747 xref: EMBL:CR936875 xref: EMBL:Y07595 xref: HGNC:HGNC:4658 xref: UniGene:Hs.485070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049269 ! TF2H4_HUMAN relationship: codes_for CCO:B0053722 ! A2ABL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015034 name: BRF1_human def: "Transcription factor IIIB 90 kDa subunit gene" [UniProtKB:Q92994] synonym: "BRF" EXACT [UniProtKB:Q92994] synonym: "GTF3B" EXACT [UniProtKB:Q92994] synonym: "TAF3B2" EXACT [UniProtKB:Q92994] synonym: "TAF3C" EXACT [UniProtKB:Q92994] xref: EMBL:AJ297406 xref: EMBL:AJ297407 xref: EMBL:AJ297408 xref: EMBL:BC016743 xref: EMBL:BC071637 xref: EMBL:BC086856 xref: EMBL:BC103860 xref: EMBL:BC103861 xref: EMBL:BC133655 xref: EMBL:CH471061 xref: EMBL:U28838 xref: EMBL:U75276 xref: HGNC:HGNC:11551 xref: UniGene:Hs.424484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050546 ! TF3B_HUMAN relationship: codes_for CCO:B0050549 ! Q96KX3_HUMAN relationship: codes_for CCO:B0053746 ! A3KN61_HUMAN relationship: codes_for CCO:B0056274 ! Q3SYD7_HUMAN relationship: codes_for CCO:B0056275 ! Q3SYD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015036 name: TFE3_human def: "Transcription factor E3 gene" [UniProtKB:P19532] xref: EMBL:BX572102 xref: EMBL:X51330 xref: EMBL:X96717 xref: EMBL:X97160 xref: EMBL:X97161 xref: EMBL:X97162 xref: EMBL:X99721 xref: HGNC:HGNC:11752 xref: UniGene:Hs.274184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049262 ! TFE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015037 name: TFEB_human def: "Transcription factor EB gene" [UniProtKB:P19484] xref: EMBL:AJ608786 xref: EMBL:AK095061 xref: EMBL:AL035588 xref: EMBL:AL365205 xref: EMBL:BC006225 xref: EMBL:BC032448 xref: EMBL:M33782 xref: HGNC:HGNC:11753 xref: UniGene:Hs.485360 xref: UniGene:Hs.705396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049259 ! B0QYS6_HUMAN relationship: codes_for CCO:B0049260 ! TFEB_HUMAN relationship: codes_for CCO:B0049261 ! B0QYS7_HUMAN relationship: codes_for CCO:B0049263 ! B1AKB4_HUMAN relationship: codes_for CCO:B0049264 ! B1AKB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015039 name: TGM2_human def: "Protein-glutamine gamma-glutamyltransferase 2 gene" [UniProtKB:P21980] xref: EMBL:AL031651 xref: EMBL:BC003551 xref: EMBL:M55153 xref: EMBL:M98478 xref: EMBL:S81734 xref: HGNC:HGNC:11778 xref: UniGene:Hs.517033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048975 ! TGM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015048 name: TMCC2_human def: "Transmembrane and coiled-coil domains protein 2 gene" [UniProtKB:O75069] synonym: "hucep-11" EXACT [UniProtKB:O75069] synonym: "KIAA0481" EXACT [UniProtKB:O75069] xref: EMBL:AB001596 xref: EMBL:AB007950 xref: EMBL:AK131419 xref: HGNC:HGNC:24239 xref: UniGene:Hs.6360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051710 ! TMCC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015051 name: TMSL1_human def: "Thymosin beta-4-like protein 1 gene" [UniProtKB:Q08EQ4] xref: EMBL:BC101199 xref: EMBL:BC101200 xref: HGNC:HGNC:11883 xref: UniGene:Hs.655548 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049174 ! TMSL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015052 name: TMSL2_human def: "Thymosin beta-4-like protein 2 gene" [UniProtKB:Q2KHM7] xref: EMBL:BC104196 xref: EMBL:BC104197 xref: EMBL:BC113076 xref: HGNC:HGNC:11884 xref: UniGene:Hs.659140 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049167 ! TMSL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015053 name: TMSL3_human def: "Thymosin beta-4-like protein 3 gene" [UniProtKB:A8MW06] xref: EMBL:AC019188 xref: EMBL:CR621963 xref: HGNC:HGNC:11885 xref: UniGene:Hs.555895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049175 ! TMSL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015054 name: TMSL6_human def: "Thymosin beta-4-like protein 6 gene" [UniProtKB:A9Z1Y9] synonym: "TMSB4L" EXACT [UniProtKB:A9Z1Y9] xref: EMBL:BC112282 xref: HGNC:HGNC:11888 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049179 ! TMSL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015057 name: THPO_human def: "Thrombopoietin precursor gene" [UniProtKB:P40225] synonym: "MGDF" EXACT [UniProtKB:P40225] xref: EMBL:AB102890 xref: EMBL:D32046 xref: EMBL:D32047 xref: EMBL:L33410 xref: EMBL:L36051 xref: EMBL:L36052 xref: EMBL:S76771 xref: EMBL:U11025 xref: EMBL:U17071 xref: EMBL:U59493 xref: EMBL:U59494 xref: EMBL:U59495 xref: HGNC:HGNC:11795 xref: UniGene:Hs.1166 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049672 ! TPO_HUMAN relationship: codes_for CCO:B0049674 ! Q5FBX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015069 name: TMSB10_human def: "Thymosin beta-10 gene" [UniProtKB:P63313] synonym: "PTMB10" EXACT [UniProtKB:P63313] synonym: "THYB10" EXACT [UniProtKB:P63313] xref: EMBL:BC016025 xref: EMBL:BC016731 xref: EMBL:M20259 xref: EMBL:M92381 xref: EMBL:M92383 xref: EMBL:S54005 xref: HGNC:HGNC:11879 xref: UniGene:Hs.446574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049178 ! TYB10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015070 name: TMSB4Y_human def: "Thymosin beta-4, Y-chromosomal gene" [UniProtKB:O14604] synonym: "TB4Y" EXACT [UniProtKB:O14604] xref: EMBL:AC006371 xref: EMBL:AF000989 xref: EMBL:BC022482 xref: EMBL:BC119763 xref: EMBL:BC119764 xref: HGNC:HGNC:11882 xref: UniGene:Hs.159201 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049176 ! TYB4Y_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015075 name: UBE2K_human def: "Ubiquitin-conjugating enzyme E2 K gene" [UniProtKB:P61086] synonym: "HIP2" EXACT [UniProtKB:P61086] synonym: "LIG" EXACT [UniProtKB:P61086] xref: EMBL:AB022435 xref: EMBL:AB022436 xref: EMBL:AC105287 xref: EMBL:BC022804 xref: EMBL:BC050600 xref: EMBL:U58522 xref: HGNC:HGNC:4914 xref: UniGene:Hs.50308 xref: UniGene:Hs.593076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050171 ! UBE2K_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015077 name: VIL1_human def: "Villin-1 gene" [UniProtKB:P09327] synonym: "VIL" EXACT [UniProtKB:P09327] xref: EMBL:X04657 xref: EMBL:X12901 xref: HGNC:HGNC:12690 xref: UniGene:Hs.654595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051613 ! VILI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015078 name: VILL_human def: "Villin-like protein gene" [UniProtKB:O15195] xref: EMBL:AC105752 xref: EMBL:BC000243 xref: EMBL:BC004300 xref: EMBL:CH471055 xref: EMBL:D88154 xref: HGNC:HGNC:30906 xref: UniGene:Hs.103665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051606 ! VILL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015080 name: VWF_human def: "von Willebrand factor precursor gene" [UniProtKB:P04275] synonym: "F8VWF" EXACT [UniProtKB:P04275] xref: EMBL:K03028 xref: EMBL:M10321 xref: EMBL:M16945 xref: EMBL:M16946 xref: EMBL:M17588 xref: EMBL:M25828 xref: EMBL:M25829 xref: EMBL:M25830 xref: EMBL:M25831 xref: EMBL:M25832 xref: EMBL:M25833 xref: EMBL:M25834 xref: EMBL:M25835 xref: EMBL:M25836 xref: EMBL:M25837 xref: EMBL:M25838 xref: EMBL:M25839 xref: EMBL:M25840 xref: EMBL:M25841 xref: EMBL:M25842 xref: EMBL:M25843 xref: EMBL:M25844 xref: EMBL:M25845 xref: EMBL:M25846 xref: EMBL:M25847 xref: EMBL:M25848 xref: EMBL:M25849 xref: EMBL:M25850 xref: EMBL:M25851 xref: EMBL:M25852 xref: EMBL:M25853 xref: EMBL:M25854 xref: EMBL:M25855 xref: EMBL:M25856 xref: EMBL:M25857 xref: EMBL:M25858 xref: EMBL:M25859 xref: EMBL:M25860 xref: EMBL:M25861 xref: EMBL:M25862 xref: EMBL:M25863 xref: EMBL:M25864 xref: EMBL:M25865 xref: EMBL:M60675 xref: EMBL:U81237 xref: EMBL:X02672 xref: EMBL:X04146 xref: EMBL:X04385 xref: EMBL:X06828 xref: EMBL:X06829 xref: HGNC:HGNC:12726 xref: UniGene:Hs.440848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031878 ! VWF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015081 name: WDR1_human def: "WD repeat-containing protein 1 gene" [UniProtKB:O75083] xref: EMBL:AB010427 xref: EMBL:AF020056 xref: EMBL:AF020260 xref: EMBL:AL050108 xref: EMBL:AL110208 xref: EMBL:BC000201 xref: EMBL:BC002489 xref: EMBL:BC030541 xref: HGNC:HGNC:12754 xref: UniGene:Hs.128548 xref: UniGene:Hs.702302 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050621 ! WDR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015083 name: WISP2_human def: "WNT1-inducible-signaling pathway protein 2 precursor gene" [UniProtKB:O76076] synonym: "CCN5" EXACT [UniProtKB:O76076] synonym: "CT58" EXACT [UniProtKB:O76076] synonym: "CTGFL" EXACT [UniProtKB:O76076] synonym: "UNQ228/PRO261" EXACT [UniProtKB:O76076] xref: EMBL:AF074604 xref: EMBL:AF083500 xref: EMBL:AF100780 xref: EMBL:AL139352 xref: EMBL:AY358915 xref: EMBL:BC017782 xref: EMBL:BC058074 xref: EMBL:BC064379 xref: HGNC:HGNC:12770 xref: UniGene:Hs.592145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021695 ! Q6PEG3_HUMAN relationship: codes_for CCO:B0021699 ! WISP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015084 name: WIT1_human def: "Wilms tumor-associated protein gene" [UniProtKB:Q06250] xref: EMBL:AL049692 xref: EMBL:BC002734 xref: EMBL:M60614 xref: EMBL:X69950 xref: HGNC:HGNC:18135 xref: UniGene:Hs.567499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050818 ! WIT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015085 name: YBX2_human def: "Y-box-binding protein 2 gene" [UniProtKB:Q9Y2T7] synonym: "CSDA3" EXACT [UniProtKB:Q9Y2T7] synonym: "MSY2" EXACT [UniProtKB:Q9Y2T7] xref: EMBL:AF096834 xref: EMBL:BC033800 xref: EMBL:BC047760 xref: HGNC:HGNC:17948 xref: UniGene:Hs.567494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049899 ! YBOX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015090 name: ZNF277_human def: "Zinc finger protein 277 gene" [UniProtKB:Q9NRM2] synonym: "ZNF277P" EXACT [UniProtKB:Q9NRM2] xref: EMBL:AF209198 xref: HGNC:HGNC:13070 xref: UniGene:Hs.655904 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051775 ! ZN277_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015091 name: ZNF487_human def: "Zinc finger protein 487 gene" [UniProtKB:B1APH4] xref: EMBL:AL450326 xref: HGNC:HGNC:23488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050867 ! ZN487_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015092 name: ZNF566_human def: "Zinc finger protein 566 gene" [UniProtKB:Q969W8] xref: EMBL:AK027685 xref: EMBL:BC007064 xref: EMBL:BC104886 xref: EMBL:BC104888 xref: HGNC:HGNC:25919 xref: UniGene:Hs.646371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050112 ! ZN566_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015093 name: ZNF582_human def: "Zinc finger protein 582 gene" [UniProtKB:Q96NG8] xref: EMBL:AK055489 xref: EMBL:BC011796 xref: EMBL:BC101008 xref: EMBL:BC101009 xref: EMBL:BC101010 xref: EMBL:BC101011 xref: HGNC:HGNC:26421 xref: UniGene:Hs.244391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050113 ! ZN582_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015094 name: ZNF675_human def: "Zinc finger protein 675 gene" [UniProtKB:Q8TD23] synonym: "TIZ" EXACT [UniProtKB:Q8TD23] xref: EMBL:AK093669 xref: EMBL:AY044432 xref: HGNC:HGNC:30768 xref: UniGene:Hs.264345 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048588 ! ZN675_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015095 name: ZNF737_human def: "Zinc finger protein 737 gene" [UniProtKB:O75373] synonym: "ZNF102" EXACT [UniProtKB:O75373] xref: EMBL:AF044026 xref: EMBL:BC015765 xref: HGNC:HGNC:32468 xref: UniGene:Hs.515696 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048595 ! ZN737_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015096 name: ZNF75A_human def: "Zinc finger protein 75A gene" [UniProtKB:Q96N20] xref: EMBL:AK056091 xref: EMBL:BC119652 xref: EMBL:BC119653 xref: EMBL:X91826 xref: HGNC:HGNC:13146 xref: UniGene:Hs.513292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050221 ! ZN75A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015098 name: ZNF98_human def: "Zinc finger protein 98 gene" [UniProtKB:A6NK75] xref: EMBL:AC011516 xref: EMBL:BC110576 xref: EMBL:BC129810 xref: HGNC:HGNC:13174 xref: UniGene:Hs.660982 xref: UniGene:Hs.667355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0048590 ! ZNF98_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015099 name: ZSCAN16_human def: "Zinc finger and SCAN domain-containing protein 16 gene" [UniProtKB:Q9H4T2] synonym: "ZNF392" EXACT [UniProtKB:Q9H4T2] synonym: "ZNF435" EXACT [UniProtKB:Q9H4T2] xref: EMBL:AK025844 xref: EMBL:AL358933 xref: EMBL:BC004255 xref: HGNC:HGNC:20813 xref: UniGene:Hs.656641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049842 ! ZSC16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015125 name: CD74/ROS fusion_human def: "Tyrosine-protein kinase receptor gene" [UniProtKB:A9YLN4] xref: EMBL:EU236945 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049553 ! A9YLN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015126 name: SLC34A2/ROS fusion_human def: "Tyrosine-protein kinase receptor gene" [UniProtKB:A9YLN5] xref: EMBL:EU236946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049552 ! A9YLN5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015127 name: SLC34A2/ROS1 fusion_human def: "Tyrosine-protein kinase receptor gene" [UniProtKB:A9YLN6] xref: EMBL:EU236947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049557 ! A9YLN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015148 name: IGM_human def: "VH4 heavy chain variable region precursor gene" [UniProtKB:O95973] xref: EMBL:AF103795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049025 ! O95973_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015166 name: OPRM_human def: "Mu opioid receptor variant MOR-1C gene" [UniProtKB:Q8IWW3] xref: EMBL:AY036622 xref: EMBL:AY036623 xref: HGNC:HGNC:8156 xref: UniGene:Hs.2353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050772 ! Q8IWW3_HUMAN relationship: codes_for CCO:B0050792 ! Q8IWW4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015181 name: TMSL4_human def: "Thymosin-like 4 (HCG1780554) gene" [UniProtKB:Q5T4B6] synonym: "hCG_1780554" EXACT [UniProtKB:Q5T4B6] synonym: "RP11-339B21.6-001" EXACT [UniProtKB:Q5T4B6] xref: EMBL:AL359091 xref: EMBL:CH471090 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049166 ! Q5T4B6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015187 name: DKFZp564M2223_human def: "Putative uncharacterized protein DKFZp564M2223 gene" [UniProtKB:Q659G3] synonym: "SRP9" EXACT [UniProtKB:Q659G3] xref: EMBL:AL050363 xref: EMBL:BC106005 xref: HGNC:HGNC:11304 xref: UniGene:Hs.511425 xref: UniGene:Hs.620844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0051561 ! Q659G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015205 name: WUGSC:H_LUCA15.1_human def: "WUGSC:H_LUCA15.1 protein gene" [UniProtKB:Q6LCB5] xref: EMBL:U73166 xref: HGNC:HGNC:4385 xref: UniGene:Hs.77269 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030246 ! Q6LCB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015215 name: WUGSC:H_NH0244E06.1_human def: "WUGSC:H_NH0244E06.1 protein gene" [UniProtKB:Q75MM1] xref: EMBL:AC007277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050270 ! Q75MM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015222 name: DKFZp686N1782_human def: "Putative uncharacterized protein DKFZp686N1782 gene" [UniProtKB:Q7Z3W3] xref: EMBL:BX537386 xref: HGNC:HGNC:3539 xref: UniGene:Hs.42502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0049159 ! Q7Z3W3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015227 name: DKFZp779G118_human def: "Putative uncharacterized protein DKFZp779G118 gene" [UniProtKB:Q7Z684] xref: EMBL:BX537505 xref: HGNC:HGNC:5004 xref: UniGene:Hs.693708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050272 ! Q7Z684_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015241 name: hCG_2040518_human def: "Seven transmembrane helix receptor (HCG2040518) gene" [UniProtKB:Q8NH91] xref: EMBL:AB065494 xref: EMBL:CH471076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029019 ! Q8NH91_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015244 name: FLJ00114_human def: "FLJ00114 protein gene" [UniProtKB:Q8TES5] synonym: "ITGAX" EXACT [UniProtKB:Q8TES5] xref: EMBL:AC093520 xref: EMBL:AK074047 xref: HGNC:HGNC:6152 xref: UniGene:Hs.248472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050195 ! Q8TES5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0015264 name: FKHRL1P2_human def: "Fork head-like protein gene" [UniProtKB:Q9UPC2] xref: EMBL:AF041336 xref: HGNC:HGNC:3821 xref: UniGene:Hs.220950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050346 ! Q9UPC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016844 name: SH3BP1_human def: "SH3 domain-binding protein 1 gene" [UniProtKB:Q9Y3L3] xref: EMBL:AK124370 xref: EMBL:AL157480 xref: EMBL:BC008282 xref: EMBL:CR456576 xref: EMBL:Z83844 xref: HGNC:HGNC:10824 xref: UniGene:Hs.601143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059338 ! 3BP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016845 name: SH3BP2_human def: "SH3 domain-binding protein 2 gene" [UniProtKB:P78314] synonym: "3BP2" EXACT [UniProtKB:P78314] synonym: "RES4-23" EXACT [UniProtKB:P78314] xref: EMBL:AB000462 xref: EMBL:AB000463 xref: EMBL:AF000936 xref: EMBL:AL121750 xref: EMBL:BC022996 xref: EMBL:CH471131 xref: EMBL:U56386 xref: HGNC:HGNC:10825 xref: UniGene:Hs.167679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055636 ! 3BP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016846 name: SH3BP5_human def: "SH3 domain-binding protein 5 gene" [UniProtKB:O60239] synonym: "SAB" EXACT [UniProtKB:O60239] xref: EMBL:AB005047 xref: EMBL:AL117422 xref: EMBL:BC010123 xref: HGNC:HGNC:10827 xref: UniGene:Hs.257761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017622 ! 3BP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016847 name: EIF4EBP1_human def: "Eukaryotic translation initiation factor 4E-binding protein 1 gene" [UniProtKB:Q13541] xref: EMBL:AB044548 xref: EMBL:BC004459 xref: EMBL:BC058073 xref: EMBL:BT007162 xref: EMBL:CR456769 xref: EMBL:L36055 xref: HGNC:HGNC:3288 xref: UniGene:Hs.411641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055927 ! 4EBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016848 name: EIF4EBP2_human def: "Eukaryotic translation initiation factor 4E-binding protein 2 gene" [UniProtKB:Q13542] xref: EMBL:BC005057 xref: EMBL:BC050633 xref: EMBL:BT007317 xref: EMBL:L36056 xref: HGNC:HGNC:3289 xref: UniGene:Hs.621200 xref: UniGene:Hs.695953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055928 ! 4EBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016849 name: EIF4EBP3_human def: "Eukaryotic translation initiation factor 4E-binding protein 3 gene" [UniProtKB:O60516] xref: EMBL:AF038869 xref: EMBL:BC010881 xref: EMBL:BC069293 xref: EMBL:BC073751 xref: HGNC:HGNC:3290 xref: UniGene:Hs.653135 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054565 ! 4EBP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016850 name: HTR1A_human def: "5-hydroxytryptamine receptor 1A gene" [UniProtKB:P08908] synonym: "ADRB2RL1" EXACT [UniProtKB:P08908] synonym: "ADRBRL1" EXACT [UniProtKB:P08908] xref: EMBL:AB041403 xref: EMBL:AF498978 xref: EMBL:BC069159 xref: EMBL:M28269 xref: EMBL:M83181 xref: EMBL:X13556 xref: EMBL:X57829 xref: EMBL:Z11168 xref: HGNC:HGNC:5286 xref: UniGene:Hs.247940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054934 ! 5HT1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016851 name: HTR1B_human def: "5-hydroxytryptamine receptor 1B gene" [UniProtKB:P28222] synonym: "HTR1DB" EXACT [UniProtKB:P28222] xref: EMBL:AB041370 xref: EMBL:AL049595 xref: EMBL:AY225227 xref: EMBL:BC069065 xref: EMBL:BC096206 xref: EMBL:BC096207 xref: EMBL:BC096208 xref: EMBL:D10995 xref: EMBL:L09732 xref: EMBL:M75128 xref: EMBL:M81590 xref: EMBL:M83180 xref: EMBL:M89478 xref: HGNC:HGNC:5287 xref: UniGene:Hs.123016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055197 ! 5HT1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016852 name: HTR1E_human def: "5-hydroxytryptamine receptor 1E gene" [UniProtKB:P28566] xref: EMBL:AB041373 xref: EMBL:AF498980 xref: EMBL:AL157777 xref: EMBL:BC069751 xref: EMBL:M91467 xref: EMBL:M92826 xref: EMBL:Z11166 xref: HGNC:HGNC:5291 xref: UniGene:Hs.1611 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055205 ! 5HT1E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016853 name: HTR1F_human def: "5-hydroxytryptamine receptor 1F gene" [UniProtKB:P30939] synonym: "HTR1EL" EXACT [UniProtKB:P30939] xref: EMBL:AF498981 xref: EMBL:BC069125 xref: EMBL:L04962 xref: EMBL:L05597 xref: HGNC:HGNC:5292 xref: UniGene:Hs.248136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055226 ! 5HT1F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016854 name: HTR2A_human def: "5-hydroxytryptamine receptor 2A gene" [UniProtKB:P28223] synonym: "HTR2" EXACT [UniProtKB:P28223] xref: EMBL:AF498982 xref: EMBL:AL136958 xref: EMBL:AL160397 xref: EMBL:BC069356 xref: EMBL:BC069576 xref: EMBL:BC074848 xref: EMBL:BC074849 xref: EMBL:BC096839 xref: EMBL:M86841 xref: EMBL:S42165 xref: EMBL:S42167 xref: EMBL:S42168 xref: EMBL:S49737 xref: EMBL:S50113 xref: EMBL:S50130 xref: EMBL:S71229 xref: EMBL:X57830 xref: HGNC:HGNC:5293 xref: UniGene:Hs.654586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055198 ! 5HT2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016855 name: HTR2B_human def: "5-hydroxytryptamine receptor 2B gene" [UniProtKB:P41595] xref: EMBL:AC009407 xref: EMBL:AF156158 xref: EMBL:AF156159 xref: EMBL:AF156160 xref: EMBL:AY136751 xref: EMBL:BC063123 xref: EMBL:X77307 xref: EMBL:Z36748 xref: HGNC:HGNC:5294 xref: UniGene:Hs.421649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055343 ! 5HT2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016856 name: HTR4_human def: "5-hydroxytryptamine receptor 4 gene" [UniProtKB:Q13639] xref: EMBL:AJ011371 xref: EMBL:AJ243213 xref: EMBL:AJ278979 xref: EMBL:AJ278981 xref: EMBL:AJ278982 xref: EMBL:BC074755 xref: EMBL:Y08756 xref: EMBL:Y09586 xref: EMBL:Y10437 xref: EMBL:Y12505 xref: EMBL:Y12506 xref: EMBL:Y12507 xref: EMBL:Y13584 xref: EMBL:Z48150 xref: HGNC:HGNC:5299 xref: UniGene:Hs.483773 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055937 ! 5HT4R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016857 name: HTR5A_human def: "5-hydroxytryptamine receptor 5A gene" [UniProtKB:P47898] xref: EMBL:AF498985 xref: EMBL:BC112021 xref: EMBL:X81411 xref: EMBL:X81412 xref: HGNC:HGNC:5300 xref: UniGene:Hs.65791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055393 ! 5HT5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016858 name: HTR6_human def: "5-hydroxytryptamine receptor 6 gene" [UniProtKB:P50406] xref: EMBL:AL031727 xref: EMBL:AY429105 xref: EMBL:BC074995 xref: EMBL:BC074996 xref: EMBL:CH471134 xref: EMBL:L41147 xref: EMBL:Z49119 xref: HGNC:HGNC:5301 xref: UniGene:Hs.22180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055449 ! 5HT6R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016859 name: HTR7_human def: "5-hydroxytryptamine receptor 7 gene" [UniProtKB:P34969] xref: EMBL:AL360011 xref: EMBL:AY493988 xref: EMBL:BC047526 xref: EMBL:CH471066 xref: EMBL:L21195 xref: EMBL:U68487 xref: EMBL:U68488 xref: EMBL:U68492 xref: EMBL:U68493 xref: HGNC:HGNC:5302 xref: UniGene:Hs.73739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055272 ! 5HT7R_HUMAN relationship: codes_for CCO:B0056665 ! Q5VX04_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016860 name: A1CF_human def: "APOBEC1 complementation factor gene" [UniProtKB:Q9NQ94] synonym: "ACF" EXACT [UniProtKB:Q9NQ94] synonym: "ASP" EXACT [UniProtKB:Q9NQ94] xref: EMBL:AF209192 xref: EMBL:AF271789 xref: EMBL:AF271790 xref: EMBL:AJ272078 xref: EMBL:AJ272079 xref: EMBL:AK000324 xref: EMBL:AL512366 xref: EMBL:AL589794 xref: HGNC:HGNC:24086 xref: UniGene:Hs.499643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058866 ! A1CF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016861 name: ADORA1_human def: "Adenosine receptor A1 gene" [UniProtKB:P30542] xref: EMBL:AB004662 xref: EMBL:AC105940 xref: EMBL:AK289928 xref: EMBL:AY136746 xref: EMBL:BC026340 xref: EMBL:BT019854 xref: EMBL:CH471067 xref: EMBL:CR541749 xref: EMBL:L22214 xref: EMBL:S45235 xref: EMBL:S56143 xref: EMBL:X68485 xref: HGNC:HGNC:262 xref: UniGene:Hs.77867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055221 ! AA1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016862 name: ADORA2A_human def: "Adenosine receptor A2a gene" [UniProtKB:P29274] synonym: "ADORA2" EXACT [UniProtKB:P29274] xref: EMBL:AY136747 xref: EMBL:BC013780 xref: EMBL:BT006999 xref: EMBL:CR456367 xref: EMBL:M97370 xref: EMBL:S46950 xref: EMBL:U40770 xref: EMBL:U40771 xref: EMBL:X68486 xref: HGNC:HGNC:263 xref: UniGene:Hs.197029 xref: UniGene:Hs.700816 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055210 ! AA2AR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016863 name: ADORA2B_human def: "Adenosine receptor A2b gene" [UniProtKB:P29275] xref: EMBL:AY136748 xref: EMBL:BC025722 xref: EMBL:M97759 xref: EMBL:X68487 xref: HGNC:HGNC:264 xref: UniGene:Hs.167046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055211 ! AA2BR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016864 name: ADORA3_human def: "Adenosine A3 receptor gene" [UniProtKB:P33765] synonym: "UNQ1931/PRO4406" EXACT [UniProtKB:P33765] xref: EMBL:AL390195 xref: EMBL:AY011231 xref: EMBL:AY136749 xref: EMBL:AY358644 xref: EMBL:BC029831 xref: EMBL:L20463 xref: EMBL:L22607 xref: EMBL:L77729 xref: EMBL:L77730 xref: EMBL:X76981 xref: HGNC:HGNC:268 xref: UniGene:Hs.281342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055269 ! AA3R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016865 name: PRKAB1_human def: "5'-AMP-activated protein kinase subunit beta-1 gene" [UniProtKB:Q9Y478] synonym: "AMPK" EXACT [UniProtKB:Q9Y478] xref: EMBL:AC002563 xref: EMBL:AF022116 xref: EMBL:AJ224515 xref: EMBL:BC001007 xref: EMBL:BC001056 xref: EMBL:BC001823 xref: EMBL:BC017671 xref: EMBL:U83994 xref: EMBL:U87271 xref: EMBL:U87272 xref: EMBL:U87273 xref: EMBL:U87274 xref: EMBL:U87275 xref: EMBL:U87276 xref: EMBL:Y12556 xref: HGNC:HGNC:9378 xref: UniGene:Hs.6061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059353 ! AAKB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016866 name: PRKAB2_human def: "5'-AMP-activated protein kinase subunit beta-2 gene" [UniProtKB:O43741] xref: EMBL:AF504538 xref: EMBL:AF504539 xref: EMBL:AF504540 xref: EMBL:AF504541 xref: EMBL:AF504542 xref: EMBL:AF504543 xref: EMBL:AJ224538 xref: EMBL:AL356378 xref: EMBL:BC053610 xref: HGNC:HGNC:9379 xref: UniGene:Hs.50732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054517 ! AAKB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016867 name: PRKAG1_human def: "5'-AMP-activated protein kinase subunit gamma-1 gene" [UniProtKB:P54619] xref: EMBL:BC000358 xref: EMBL:BT007345 xref: EMBL:U42412 xref: HGNC:HGNC:9385 xref: UniGene:Hs.530862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016329 ! AAKG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016868 name: PRKAG2_human def: "5'-AMP-activated protein kinase subunit gamma-2 gene" [UniProtKB:Q9UGJ0] xref: EMBL:AB025580 xref: EMBL:AC006358 xref: EMBL:AC006966 xref: EMBL:AC093583 xref: EMBL:AF087875 xref: EMBL:AJ249976 xref: EMBL:AK001887 xref: EMBL:BC020540 xref: EMBL:BC068598 xref: EMBL:BT007127 xref: HGNC:HGNC:9386 xref: UniGene:Hs.647072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016326 ! AAKG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016869 name: PRKAG3_human def: "5'-AMP-activated protein kinase subunit gamma-3 gene" [UniProtKB:Q9UGI9] synonym: "AMPKG3" EXACT [UniProtKB:Q9UGI9] xref: EMBL:AF214519 xref: EMBL:AJ249977 xref: EMBL:BC098102 xref: EMBL:BC098255 xref: EMBL:BC098277 xref: EMBL:BC098306 xref: HGNC:HGNC:9387 xref: UniGene:Hs.591634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016331 ! AAKG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016870 name: PRKAA2_human def: "5'-AMP-activated protein kinase catalytic subunit alpha-2 gene" [UniProtKB:P54646] synonym: "AMPK" EXACT [UniProtKB:P54646] synonym: "AMPK2" EXACT [UniProtKB:P54646] xref: EMBL:AL035705 xref: EMBL:BC069680 xref: EMBL:BC069740 xref: EMBL:BC069823 xref: EMBL:U06454 xref: HGNC:HGNC:9377 xref: UniGene:Hs.437039 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055514 ! AAPK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016871 name: APBB1IP_human def: "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein gene" [UniProtKB:Q7Z5R6] synonym: "PREL1" EXACT [UniProtKB:Q7Z5R6] synonym: "RARP1" EXACT [UniProtKB:Q7Z5R6] synonym: "RIAM" EXACT [UniProtKB:Q7Z5R6] xref: EMBL:AB085852 xref: EMBL:AK000812 xref: EMBL:AL160287 xref: EMBL:AL355798 xref: EMBL:AY152730 xref: EMBL:BC054516 xref: HGNC:HGNC:17379 xref: UniGene:Hs.310421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028910 ! Q9NWJ6_HUMAN relationship: codes_for CCO:B0028914 ! AB1IP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016872 name: ABCA2_human def: "ATP-binding cassette sub-family A member 2 gene" [UniProtKB:Q9BZC7] synonym: "ABC2" EXACT [UniProtKB:Q9BZC7] synonym: "KIAA1062" EXACT [UniProtKB:Q9BZC7] xref: EMBL:AB028985 xref: EMBL:AB177854 xref: EMBL:AF327658 xref: EMBL:AF327659 xref: EMBL:AF327660 xref: EMBL:AF327661 xref: EMBL:AF327662 xref: EMBL:AF327663 xref: EMBL:AF327664 xref: EMBL:AF327665 xref: EMBL:AF327666 xref: EMBL:AF327667 xref: EMBL:AF327668 xref: EMBL:AF327669 xref: EMBL:AF327670 xref: EMBL:AF327671 xref: EMBL:AF327672 xref: EMBL:AF327673 xref: EMBL:AF327674 xref: EMBL:AF327675 xref: EMBL:AF327676 xref: EMBL:AF327677 xref: EMBL:AF327678 xref: EMBL:AF327679 xref: EMBL:AF327680 xref: EMBL:AF327681 xref: EMBL:AF327682 xref: EMBL:AF327683 xref: EMBL:AF327684 xref: EMBL:AF327685 xref: EMBL:AF327686 xref: EMBL:AF327687 xref: EMBL:AF327688 xref: EMBL:AF327689 xref: EMBL:AF327690 xref: EMBL:AF327691 xref: EMBL:AF327692 xref: EMBL:AF327693 xref: EMBL:AF327694 xref: EMBL:AF327695 xref: EMBL:AF327696 xref: EMBL:AF327697 xref: EMBL:AF327698 xref: EMBL:AF327699 xref: EMBL:AF327700 xref: EMBL:AF327701 xref: EMBL:AF327702 xref: EMBL:AF327703 xref: EMBL:AF327704 xref: EMBL:AF327705 xref: EMBL:AL807752 xref: HGNC:HGNC:32 xref: UniGene:Hs.421202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058595 ! ABCA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016873 name: ABCG1_human def: "ATP-binding cassette sub-family G member 1 gene" [UniProtKB:P45844] synonym: "ABC8" EXACT [UniProtKB:P45844] synonym: "WHT1" EXACT [UniProtKB:P45844] xref: EMBL:AB038161 xref: EMBL:AF323640 xref: EMBL:AF323642 xref: EMBL:AF323643 xref: EMBL:AF323644 xref: EMBL:AF323645 xref: EMBL:AF323646 xref: EMBL:AF323647 xref: EMBL:AF323648 xref: EMBL:AF323649 xref: EMBL:AF323650 xref: EMBL:AF323651 xref: EMBL:AF323652 xref: EMBL:AF323653 xref: EMBL:AF323654 xref: EMBL:AF323655 xref: EMBL:AF323656 xref: EMBL:AF323657 xref: EMBL:AF323658 xref: EMBL:AF323660 xref: EMBL:AF323661 xref: EMBL:AF323662 xref: EMBL:AF323663 xref: EMBL:AF323664 xref: EMBL:AJ289137 xref: EMBL:AJ289138 xref: EMBL:AJ289139 xref: EMBL:AJ289140 xref: EMBL:AJ289141 xref: EMBL:AJ289142 xref: EMBL:AJ289143 xref: EMBL:AJ289144 xref: EMBL:AJ289145 xref: EMBL:AJ289146 xref: EMBL:AJ289147 xref: EMBL:AJ289148 xref: EMBL:AJ289149 xref: EMBL:AJ289150 xref: EMBL:AJ289151 xref: EMBL:AP001746 xref: EMBL:AY048757 xref: EMBL:BC029158 xref: EMBL:U34919 xref: EMBL:X91249 xref: HGNC:HGNC:73 xref: UniGene:Hs.124649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055371 ! ABCG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016874 name: ABHD2_human def: "Abhydrolase domain-containing protein 2 gene" [UniProtKB:P08910] synonym: "LABH2" EXACT [UniProtKB:P08910] xref: EMBL:AF546700 xref: EMBL:AK222841 xref: EMBL:AK223083 xref: EMBL:BC019248 xref: EMBL:BC090052 xref: EMBL:X12433 xref: HGNC:HGNC:18717 xref: UniGene:Hs.122337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054935 ! ABHD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016875 name: ABRA_human def: "Actin-binding Rho-activating protein gene" [UniProtKB:Q8N0Z2] xref: EMBL:AF503617 xref: EMBL:AK092694 xref: EMBL:BC105103 xref: EMBL:BC105105 xref: HGNC:HGNC:30655 xref: UniGene:Hs.374668 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057419 ! ABRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016876 name: ABR_human def: "Active breakpoint cluster region-related protein gene" [UniProtKB:Q12979] xref: EMBL:L19704 xref: EMBL:L19705 xref: EMBL:U01147 xref: HGNC:HGNC:81 xref: UniGene:Hs.159306 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055861 ! ABR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016877 name: ABT1_human def: "Activator of basal transcription 1 gene" [UniProtKB:Q9ULW3] xref: EMBL:AB027258 xref: EMBL:AL513548 xref: EMBL:BC048812 xref: EMBL:BC066313 xref: HGNC:HGNC:17369 xref: UniGene:Hs.254406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059235 ! ABT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016878 name: ABTB2_human def: "Ankyrin repeat and BTB/POZ domain-containing protein 2 gene" [UniProtKB:Q8N961] xref: EMBL:AK091560 xref: EMBL:AK095632 xref: EMBL:BC093968 xref: EMBL:BX640841 xref: HGNC:HGNC:23842 xref: UniGene:Hs.23361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057532 ! ABTB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016879 name: ACACB_human def: "Acetyl-CoA carboxylase 2 gene" [UniProtKB:O00763] synonym: "ACC2" EXACT [UniProtKB:O00763] synonym: "ACCB" EXACT [UniProtKB:O00763] xref: EMBL:AJ575431 xref: EMBL:AJ575592 xref: EMBL:AY382667 xref: EMBL:DQ493870 xref: EMBL:U34591 xref: EMBL:U89344 xref: HGNC:HGNC:85 xref: UniGene:Hs.234898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054342 ! ACACB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016880 name: ACAD8_human def: "Isobutyryl-CoA dehydrogenase, mitochondrial precursor gene" [UniProtKB:Q9UKU7] synonym: "ARC42" EXACT [UniProtKB:Q9UKU7] synonym: "IBD" EXACT [UniProtKB:Q9UKU7] xref: EMBL:AF126245 xref: EMBL:AF260679 xref: EMBL:AF260680 xref: EMBL:AF260681 xref: EMBL:AF260682 xref: EMBL:AF260683 xref: EMBL:AF260684 xref: EMBL:AF260685 xref: EMBL:AF260686 xref: EMBL:AF260687 xref: EMBL:AF260688 xref: EMBL:AF260689 xref: EMBL:AK000359 xref: EMBL:BC001964 xref: HGNC:HGNC:87 xref: UniGene:Hs.14791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059203 ! ACAD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016881 name: ACCN2_human def: "Amiloride-sensitive cation channel 2, neuronal gene" [UniProtKB:P78348] synonym: "ASIC1" EXACT [UniProtKB:P78348] synonym: "BNAC2" EXACT [UniProtKB:P78348] xref: EMBL:BC013891 xref: EMBL:U78180 xref: EMBL:U78181 xref: HGNC:HGNC:100 xref: UniGene:Hs.274361 xref: UniGene:Hs.647113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055639 ! ACCN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016882 name: ACCN3_human def: "Amiloride-sensitive cation channel 3 gene" [UniProtKB:Q9UHC3] synonym: "ASIC3" EXACT [UniProtKB:Q9UHC3] synonym: "SLNAC1" EXACT [UniProtKB:Q9UHC3] synonym: "TNAC1" EXACT [UniProtKB:Q9UHC3] xref: EMBL:AB010575 xref: EMBL:AB209421 xref: EMBL:AF057711 xref: EMBL:AF095897 xref: EMBL:AF195024 xref: EMBL:AF195025 xref: HGNC:HGNC:101 xref: UniGene:Hs.647113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059134 ! ACCN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016883 name: ACE2_human def: "Angiotensin-converting enzyme 2 precursor gene" [UniProtKB:Q9BYF1] synonym: "UNQ868/PRO1885" EXACT [UniProtKB:Q9BYF1] xref: EMBL:AB046569 xref: EMBL:AB193259 xref: EMBL:AB193260 xref: EMBL:AF241254 xref: EMBL:AF291820 xref: EMBL:AL110224 xref: EMBL:AY217547 xref: EMBL:AY358714 xref: EMBL:AY623811 xref: EMBL:BC039902 xref: EMBL:BC048094 xref: HGNC:HGNC:13557 xref: UniGene:Hs.178098 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058578 ! ACE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016884 name: ACHE_human def: "Acetylcholinesterase precursor gene" [UniProtKB:P22303] xref: EMBL:AC011895 xref: EMBL:AF312032 xref: EMBL:AF334270 xref: EMBL:AK291321 xref: EMBL:AY750146 xref: EMBL:BC036813 xref: EMBL:BC094752 xref: EMBL:BC105060 xref: EMBL:BC105062 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: EMBL:M55040 xref: EMBL:S71129 xref: HGNC:HGNC:108 xref: UniGene:Hs.154495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055143 ! ACES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016885 name: ACE_human def: "Angiotensin-converting enzyme precursor gene" [UniProtKB:P12821] synonym: "DCP" EXACT [UniProtKB:P12821] synonym: "DCP1" EXACT [UniProtKB:P12821] xref: EMBL:AB208971 xref: EMBL:AF118569 xref: EMBL:AY436326 xref: EMBL:J04144 xref: EMBL:M26657 xref: EMBL:X16295 xref: HGNC:HGNC:2707 xref: UniGene:Hs.654434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055006 ! ACE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016886 name: CHRNA10_human def: "Neuronal acetylcholine receptor subunit alpha-10 precursor gene" [UniProtKB:Q9GZZ6] synonym: "NACHRA10" EXACT [UniProtKB:Q9GZZ6] xref: EMBL:AF199235 xref: EMBL:AF327367 xref: EMBL:AJ278118 xref: EMBL:AJ295237 xref: HGNC:HGNC:13800 xref: UniGene:Hs.157714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058646 ! ACH10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016887 name: CHRNA2_human def: "Neuronal acetylcholine receptor subunit alpha-2 precursor gene" [UniProtKB:Q15822] xref: EMBL:AF311103 xref: EMBL:BC153866 xref: EMBL:U62431 xref: EMBL:Y16281 xref: HGNC:HGNC:1956 xref: UniGene:Hs.57718 xref: UniGene:Hs.700504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032809 ! ACHA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016888 name: CHRNA3_human def: "Neuronal acetylcholine receptor subunit alpha-3 precursor gene" [UniProtKB:P32297] synonym: "NACHRA3" EXACT [UniProtKB:P32297] xref: EMBL:AF385584 xref: EMBL:AJ007783 xref: EMBL:AJ007784 xref: EMBL:AJ007785 xref: EMBL:AJ007786 xref: EMBL:AJ007787 xref: EMBL:BC000513 xref: EMBL:BC001642 xref: EMBL:BC002996 xref: EMBL:M37981 xref: EMBL:M86383 xref: EMBL:U62432 xref: EMBL:X53559 xref: EMBL:Y08418 xref: HGNC:HGNC:1957 xref: UniGene:Hs.89605 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032804 ! ACHA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016889 name: CHRNA4_human def: "Neuronal acetylcholine receptor subunit alpha-4 precursor gene" [UniProtKB:P43681] synonym: "NACRA4" EXACT [UniProtKB:P43681] xref: EMBL:AL121827 xref: EMBL:BC096290 xref: EMBL:DQ093071 xref: EMBL:L35901 xref: EMBL:U62433 xref: EMBL:X87629 xref: EMBL:X89741 xref: EMBL:X89742 xref: EMBL:X89743 xref: EMBL:X89744 xref: EMBL:X89745 xref: EMBL:X89746 xref: EMBL:Y08421 xref: HGNC:HGNC:1958 xref: UniGene:Hs.10734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055368 ! ACHA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016890 name: CHRNA5_human def: "Neuronal acetylcholine receptor subunit alpha-5 precursor gene" [UniProtKB:P30532] synonym: "NACHRA5" EXACT [UniProtKB:P30532] xref: EMBL:AJ306481 xref: EMBL:AJ306482 xref: EMBL:AJ306483 xref: EMBL:AJ306484 xref: EMBL:AJ306485 xref: EMBL:AJ306486 xref: EMBL:BC033639 xref: EMBL:M83712 xref: EMBL:U62434 xref: EMBL:Y08419 xref: HGNC:HGNC:1959 xref: UniGene:Hs.1614 xref: UniGene:Hs.625152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032806 ! ACHA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016891 name: CHRNA6_human def: "Neuronal acetylcholine receptor subunit alpha-6 precursor gene" [UniProtKB:Q15825] xref: EMBL:AB079251 xref: EMBL:BC014456 xref: EMBL:U62435 xref: EMBL:Y16282 xref: HGNC:HGNC:15963 xref: UniGene:Hs.103128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032798 ! ACHA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016892 name: CHRNA7_human def: "Neuronal acetylcholine receptor subunit alpha-7 precursor gene" [UniProtKB:P36544] synonym: "NACHRA7" EXACT [UniProtKB:P36544] xref: EMBL:AF332758 xref: EMBL:AF385585 xref: EMBL:L25827 xref: EMBL:U40583 xref: EMBL:U62436 xref: EMBL:X70297 xref: EMBL:Y08420 xref: EMBL:Z23141 xref: HGNC:HGNC:1960 xref: UniGene:Hs.511772 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055310 ! ACHA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016893 name: CHRNA1_human def: "Acetylcholine receptor subunit alpha precursor gene" [UniProtKB:P02708] synonym: "ACHRA" EXACT [UniProtKB:P02708] synonym: "CHNRA" EXACT [UniProtKB:P02708] xref: EMBL:S77094 xref: EMBL:X02502 xref: EMBL:X02503 xref: EMBL:X02504 xref: EMBL:X02505 xref: EMBL:X02506 xref: EMBL:X02507 xref: EMBL:X02508 xref: EMBL:X17104 xref: EMBL:X70108 xref: EMBL:Y00762 xref: HGNC:HGNC:1955 xref: UniGene:Hs.434479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054868 ! ACHA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016894 name: CHRNB2_human def: "Neuronal acetylcholine receptor subunit beta-2 precursor gene" [UniProtKB:P17787] xref: EMBL:AF077186 xref: EMBL:AJ001935 xref: EMBL:AJ001936 xref: EMBL:AJ001937 xref: EMBL:AJ001938 xref: EMBL:AJ001939 xref: EMBL:BC075040 xref: EMBL:BC075041 xref: EMBL:U62437 xref: EMBL:X53179 xref: EMBL:Y08415 xref: HGNC:HGNC:1962 xref: UniGene:Hs.2306 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032807 ! ACHB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016895 name: CHRNB3_human def: "Neuronal acetylcholine receptor subunit beta-3 precursor gene" [UniProtKB:Q05901] xref: EMBL:AF140760 xref: EMBL:AF140761 xref: EMBL:AF140762 xref: EMBL:AF140763 xref: EMBL:AF140764 xref: EMBL:AF140765 xref: EMBL:BC069681 xref: EMBL:BC069703 xref: EMBL:BC069788 xref: EMBL:U62438 xref: EMBL:X67513 xref: EMBL:Y08417 xref: HGNC:HGNC:1963 xref: UniGene:Hs.654576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032799 ! ACHB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016896 name: CHRNB4_human def: "Neuronal acetylcholine receptor subunit beta-4 precursor gene" [UniProtKB:P30926] xref: EMBL:AF306325 xref: EMBL:AF306326 xref: EMBL:AF306327 xref: EMBL:AF306328 xref: EMBL:AF306329 xref: EMBL:AF453877 xref: EMBL:AJ306454 xref: EMBL:AJ306455 xref: EMBL:AJ306456 xref: EMBL:AJ306457 xref: EMBL:AJ306458 xref: EMBL:AJ306459 xref: EMBL:BC096080 xref: EMBL:BC096082 xref: EMBL:U48861 xref: EMBL:U62439 xref: EMBL:X68275 xref: EMBL:Y08416 xref: HGNC:HGNC:1964 xref: UniGene:Hs.624178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032797 ! ACHB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016897 name: ACIN1_human def: "Apoptotic chromatin condensation inducer in the nucleus gene" [UniProtKB:Q9UKV3] synonym: "ACINUS" EXACT [UniProtKB:Q9UKV3] synonym: "KIAA0670" EXACT [UniProtKB:Q9UKV3] xref: EMBL:AB014570 xref: EMBL:AF124726 xref: EMBL:AF124727 xref: EMBL:AF124728 xref: EMBL:AL050382 xref: EMBL:BX247975 xref: HGNC:HGNC:17066 xref: UniGene:Hs.124490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059205 ! ACINU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016898 name: CHRM1_human def: "Muscarinic acetylcholine receptor M1 gene" [UniProtKB:P11229] xref: EMBL:AF498915 xref: EMBL:BC007740 xref: EMBL:BC022984 xref: EMBL:X15263 xref: EMBL:X52068 xref: EMBL:Y00508 xref: HGNC:HGNC:1950 xref: UniGene:Hs.632119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054986 ! ACM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016899 name: CHRM2_human def: "Muscarinic acetylcholine receptor M2 gene" [UniProtKB:P08172] xref: EMBL:AB041391 xref: EMBL:AF498916 xref: EMBL:BC095547 xref: EMBL:BC106741 xref: EMBL:BC106742 xref: EMBL:M16404 xref: EMBL:X15264 xref: HGNC:HGNC:1951 xref: UniGene:Hs.535891 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054923 ! ACM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016900 name: CHRM3_human def: "Muscarinic acetylcholine receptor M3 gene" [UniProtKB:P20309] xref: EMBL:AB041395 xref: EMBL:AF279779 xref: EMBL:AF498917 xref: EMBL:AL356361 xref: EMBL:BC096844 xref: EMBL:BC121026 xref: EMBL:U29589 xref: EMBL:X15266 xref: HGNC:HGNC:1952 xref: UniGene:Hs.7138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054259 ! B1AN12_HUMAN relationship: codes_for CCO:B0055115 ! ACM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016901 name: CHRM4_human def: "Muscarinic acetylcholine receptor M4 gene" [UniProtKB:P08173] xref: EMBL:AF498918 xref: EMBL:BC095546 xref: EMBL:BC119775 xref: EMBL:BC119817 xref: EMBL:M16405 xref: EMBL:X15265 xref: HGNC:HGNC:1953 xref: UniGene:Hs.248100 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054924 ! ACM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016902 name: CHRM5_human def: "Muscarinic acetylcholine receptor M5 gene" [UniProtKB:P08912] xref: EMBL:AB084282 xref: EMBL:AF026263 xref: EMBL:AF385591 xref: EMBL:AF498919 xref: EMBL:M80333 xref: HGNC:HGNC:1954 xref: UniGene:Hs.584747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054936 ! ACM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016903 name: ACOT11_human def: "Acyl-coenzyme A thioesterase 11 gene" [UniProtKB:Q8WXI4] synonym: "BFIT" EXACT [UniProtKB:Q8WXI4] synonym: "KIAA0707" EXACT [UniProtKB:Q8WXI4] synonym: "THEA" EXACT [UniProtKB:Q8WXI4] xref: EMBL:AB014607 xref: EMBL:AF416921 xref: EMBL:AF416922 xref: EMBL:AK023937 xref: EMBL:BC001517 xref: HGNC:HGNC:18156 xref: UniGene:Hs.234786 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058024 ! ACO11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016904 name: ACSL1_human def: "Long-chain-fatty-acid--CoA ligase 1 gene" [UniProtKB:P33121] synonym: "FACL1" EXACT [UniProtKB:P33121] synonym: "FACL2" EXACT [UniProtKB:P33121] synonym: "LACS" EXACT [UniProtKB:P33121] synonym: "LACS1" EXACT [UniProtKB:P33121] synonym: "LACS2" EXACT [UniProtKB:P33121] xref: EMBL:AK096117 xref: EMBL:BC026290 xref: EMBL:BC050073 xref: EMBL:D10040 xref: EMBL:L09229 xref: HGNC:HGNC:3569 xref: UniGene:Hs.406678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055264 ! ACSL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016905 name: ACSL6_human def: "Long-chain-fatty-acid--CoA ligase 6 gene" [UniProtKB:Q9UKU0] synonym: "ACS2" EXACT [UniProtKB:Q9UKU0] synonym: "FACL6" EXACT [UniProtKB:Q9UKU0] synonym: "KIAA0837" EXACT [UniProtKB:Q9UKU0] synonym: "LACS5" EXACT [UniProtKB:Q9UKU0] xref: EMBL:AB020644 xref: EMBL:AC034228 xref: EMBL:AF099740 xref: EMBL:AF129166 xref: HGNC:HGNC:16496 xref: UniGene:Hs.14945 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059201 ! ACSL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016906 name: ADAM10_human def: "ADAM 10 precursor gene" [UniProtKB:O14672] synonym: "KUZ" EXACT [UniProtKB:O14672] synonym: "MADM" EXACT [UniProtKB:O14672] xref: EMBL:AF009615 xref: EMBL:Z48579 xref: HGNC:HGNC:188 xref: UniGene:Hs.578508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054364 ! ADA10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016907 name: ADRA2A_human def: "Alpha-2A adrenergic receptor gene" [UniProtKB:P08913] synonym: "ADRA2R" EXACT [UniProtKB:P08913] synonym: "ADRAR" EXACT [UniProtKB:P08913] xref: EMBL:AF262016 xref: EMBL:AF281308 xref: EMBL:AF284095 xref: EMBL:AF316894 xref: EMBL:AL158163 xref: EMBL:AY032736 xref: EMBL:BC035047 xref: EMBL:BC050414 xref: EMBL:DQ149926 xref: EMBL:DQ285607 xref: EMBL:M18415 xref: EMBL:M23533 xref: HGNC:HGNC:281 xref: UniGene:Hs.249159 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054937 ! ADA2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016908 name: ADRA2C_human def: "Alpha-2C adrenergic receptor gene" [UniProtKB:P18825] synonym: "ADRA2L2" EXACT [UniProtKB:P18825] synonym: "ADRA2RL2" EXACT [UniProtKB:P18825] xref: EMBL:AF280399 xref: EMBL:AF280400 xref: EMBL:AY455666 xref: EMBL:AY605898 xref: EMBL:D13538 xref: EMBL:J03853 xref: EMBL:U72648 xref: EMBL:X59684 xref: HGNC:HGNC:283 xref: UniGene:Hs.123022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055104 ! ADA2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016909 name: ADA_human def: "Adenosine deaminase gene" [UniProtKB:P00813] xref: EMBL:AK223397 xref: EMBL:AL139352 xref: EMBL:BC007678 xref: EMBL:BC040226 xref: EMBL:M13792 xref: EMBL:X02189 xref: EMBL:X02190 xref: EMBL:X02191 xref: EMBL:X02192 xref: EMBL:X02193 xref: EMBL:X02194 xref: EMBL:X02195 xref: EMBL:X02196 xref: EMBL:X02197 xref: EMBL:X02198 xref: EMBL:X02199 xref: EMBL:X02994 xref: EMBL:Z97053 xref: HGNC:HGNC:186 xref: UniGene:Hs.654536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054829 ! ADA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016910 name: ADCY1_human def: "Adenylate cyclase type 1 gene" [UniProtKB:Q08828] xref: EMBL:AC069008 xref: EMBL:AC091439 xref: EMBL:L05500 xref: HGNC:HGNC:232 xref: UniGene:Hs.192215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055794 ! ADCY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016911 name: ADCY5_human def: "Adenylate cyclase type 5 gene" [UniProtKB:O95622] xref: EMBL:AC025571 xref: EMBL:AF497517 xref: EMBL:BK000371 xref: EMBL:U65473 xref: HGNC:HGNC:236 xref: UniGene:Hs.593293 xref: UniGene:Hs.655144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054773 ! ADCY5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016912 name: ADCY6_human def: "Adenylate cyclase type 6 gene" [UniProtKB:O43306] synonym: "KIAA0422" EXACT [UniProtKB:O43306] xref: EMBL:AB007882 xref: EMBL:AF250226 xref: EMBL:BC064923 xref: HGNC:HGNC:237 xref: UniGene:Hs.525401 xref: UniGene:Hs.694408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054469 ! ADCY6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016913 name: ADCY8_human def: "Adenylate cyclase type 8 gene" [UniProtKB:P40145] xref: EMBL:DQ104739 xref: EMBL:M83533 xref: EMBL:Z35309 xref: HGNC:HGNC:239 xref: UniGene:Hs.591859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055325 ! ADCY8_HUMAN relationship: codes_for CCO:B0056310 ! Q4F7X0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016914 name: ADCY9_human def: "Adenylate cyclase type 9 gene" [UniProtKB:O60503] synonym: "KIAA0520" EXACT [UniProtKB:O60503] xref: EMBL:AB011092 xref: EMBL:AF036927 xref: EMBL:AJ133123 xref: EMBL:AY028949 xref: EMBL:AY028950 xref: EMBL:AY028951 xref: EMBL:AY028952 xref: EMBL:AY028953 xref: EMBL:AY028954 xref: EMBL:AY028955 xref: EMBL:AY028956 xref: EMBL:AY028957 xref: EMBL:AY028959 xref: EMBL:DQ005545 xref: EMBL:DQ008441 xref: HGNC:HGNC:240 xref: UniGene:Hs.391860 xref: UniGene:Hs.610484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054563 ! ADCY9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016915 name: ADCY10_human def: "Adenylate cyclase type 10 gene" [UniProtKB:Q96PN6] synonym: "SAC" EXACT [UniProtKB:Q96PN6] xref: EMBL:AF176813 xref: EMBL:AF271058 xref: EMBL:AF299350 xref: EMBL:AF331033 xref: EMBL:AL035122 xref: EMBL:BC117366 xref: EMBL:BC117372 xref: EMBL:CH471067 xref: EMBL:Z97876 xref: EMBL:Z99943 xref: HGNC:HGNC:21285 xref: UniGene:Hs.320892 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058339 ! ADCYA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016916 name: ADIG_human def: "Adipogenin gene" [UniProtKB:Q0VDE8] xref: EMBL:AL035419 xref: EMBL:BC119704 xref: EMBL:BC119705 xref: HGNC:HGNC:28606 xref: UniGene:Hs.368028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055824 ! ADIG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016917 name: ADIPOQ_human def: "Adiponectin precursor gene" [UniProtKB:Q15848] synonym: "ACDC" EXACT [UniProtKB:Q15848] synonym: "ACRP30" EXACT [UniProtKB:Q15848] synonym: "APM1" EXACT [UniProtKB:Q15848] synonym: "GBP28" EXACT [UniProtKB:Q15848] xref: EMBL:AB012165 xref: EMBL:AJ131460 xref: EMBL:AJ131461 xref: EMBL:BC054496 xref: EMBL:BC096308 xref: EMBL:BC096309 xref: EMBL:BC096310 xref: EMBL:BC096311 xref: EMBL:D45371 xref: HGNC:HGNC:13633 xref: UniGene:Hs.80485 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056116 ! ADIPO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016918 name: ADM_human def: "ADM precursor gene" [UniProtKB:P35318] synonym: "AM" EXACT [UniProtKB:P35318] xref: EMBL:BC015961 xref: EMBL:BT006902 xref: EMBL:CR541995 xref: EMBL:D14874 xref: EMBL:D43639 xref: EMBL:DQ143945 xref: EMBL:S73906 xref: HGNC:HGNC:259 xref: UniGene:Hs.441047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055286 ! ADML_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016919 name: ADNP2_human def: "ADNP homeobox protein 2 gene" [UniProtKB:Q6IQ32] synonym: "KIAA0863" EXACT [UniProtKB:Q6IQ32] synonym: "ZNF508" EXACT [UniProtKB:Q6IQ32] xref: EMBL:AB020670 xref: EMBL:AK022688 xref: EMBL:BC071589 xref: HGNC:HGNC:23803 xref: UniGene:Hs.131915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056827 ! ADNP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016920 name: ADNP_human def: "Activity-dependent neuroprotector homeobox protein gene" [UniProtKB:Q9H2P0] synonym: "ADNP1" EXACT [UniProtKB:Q9H2P0] synonym: "KIAA0784" EXACT [UniProtKB:Q9H2P0] xref: EMBL:AB018327 xref: EMBL:AF250860 xref: EMBL:AL034553 xref: EMBL:AL080163 xref: EMBL:BC090933 xref: HGNC:HGNC:15766 xref: UniGene:Hs.570355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058688 ! ADNP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016921 name: ADIPOR1_human def: "Adiponectin receptor protein 1 gene" [UniProtKB:Q96A54] synonym: "CGI-45" EXACT [UniProtKB:Q96A54] synonym: "PAQR1" EXACT [UniProtKB:Q96A54] xref: EMBL:AF151803 xref: EMBL:BC001594 xref: EMBL:BC010743 xref: HGNC:HGNC:24040 xref: UniGene:Hs.5298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021461 ! ADR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016922 name: ADIPOR2_human def: "Adiponectin receptor protein 2 gene" [UniProtKB:Q86V24] synonym: "PAQR2" EXACT [UniProtKB:Q86V24] xref: EMBL:AK025085 xref: EMBL:AK127196 xref: EMBL:AK128511 xref: EMBL:BC051858 xref: HGNC:HGNC:24041 xref: UniGene:Hs.371642 xref: UniGene:Hs.645880 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021450 ! ADR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016923 name: ADRB1_human def: "Beta-1 adrenergic receptor gene" [UniProtKB:P08588] synonym: "ADRB1R" EXACT [UniProtKB:P08588] synonym: "B1AR" EXACT [UniProtKB:P08588] xref: EMBL:AF169006 xref: EMBL:AF169007 xref: EMBL:AL355543 xref: EMBL:AY567837 xref: EMBL:J03019 xref: HGNC:HGNC:285 xref: UniGene:Hs.695932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054929 ! ADRB1_HUMAN relationship: codes_for CCO:B0056585 ! Q5T5Y4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016924 name: ADRB2_human def: "Beta-2 adrenergic receptor gene" [UniProtKB:P07550] synonym: "ADRB2R" EXACT [UniProtKB:P07550] synonym: "B2AR" EXACT [UniProtKB:P07550] xref: EMBL:AF022953 xref: EMBL:AF022954 xref: EMBL:AF022955 xref: EMBL:AF022956 xref: EMBL:AF169225 xref: EMBL:AF202305 xref: EMBL:AF203386 xref: EMBL:AY136741 xref: EMBL:DQ094845 xref: EMBL:J02960 xref: EMBL:M15169 xref: EMBL:X04827 xref: EMBL:Y00106 xref: HGNC:HGNC:286 xref: UniGene:Hs.591251 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054914 ! ADRB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016925 name: ADRB3_human def: "Beta-3 adrenergic receptor gene" [UniProtKB:P13945] synonym: "ADRB3R" EXACT [UniProtKB:P13945] synonym: "B3AR" EXACT [UniProtKB:P13945] xref: EMBL:AY487247 xref: EMBL:BC075017 xref: EMBL:DQ104441 xref: EMBL:M29932 xref: EMBL:S53291 xref: EMBL:X70811 xref: EMBL:X70812 xref: EMBL:X72861 xref: HGNC:HGNC:288 xref: UniGene:Hs.2549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055020 ! ADRB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016926 name: AEBP1_human def: "Adipocyte enhancer-binding protein 1 precursor gene" [UniProtKB:Q8IUX7] synonym: "ACLP" EXACT [UniProtKB:Q8IUX7] xref: EMBL:AB209744 xref: EMBL:AF053944 xref: EMBL:AK127541 xref: EMBL:BC038588 xref: EMBL:CH236960 xref: EMBL:CH471128 xref: EMBL:D86479 xref: HGNC:HGNC:303 xref: UniGene:Hs.439463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057330 ! AEBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016927 name: AEBP2_human def: "Zinc finger protein AEBP2 gene" [UniProtKB:Q6ZN18] xref: EMBL:AB209384 xref: EMBL:AK131361 xref: EMBL:AK131410 xref: EMBL:BC015624 xref: EMBL:BC022220 xref: EMBL:CH471094 xref: HGNC:HGNC:24051 xref: UniGene:Hs.126497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057006 ! AEBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016928 name: AFF3_human def: "AF4/FMR2 family member 3 gene" [UniProtKB:P51826] synonym: "LAF4" EXACT [UniProtKB:P51826] xref: EMBL:AB209634 xref: EMBL:AC010736 xref: EMBL:AC018690 xref: EMBL:AC073118 xref: EMBL:AC092667 xref: EMBL:BC036895 xref: EMBL:U34360 xref: HGNC:HGNC:6473 xref: UniGene:Hs.444414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055482 ! AFF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016929 name: GLA_human def: "Alpha-galactosidase A precursor gene" [UniProtKB:P06280] xref: EMBL:AL035422 xref: EMBL:BC002689 xref: EMBL:D00039 xref: EMBL:M13571 xref: EMBL:M18242 xref: EMBL:M20317 xref: EMBL:U78027 xref: EMBL:X05790 xref: EMBL:X14448 xref: EMBL:X16889 xref: HGNC:HGNC:4296 xref: UniGene:Hs.69089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054902 ! AGAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016930 name: AGGF1_human def: "Angiogenic factor with G patch and FHA domains 1 gene" [UniProtKB:Q8N302] synonym: "GPATC7" EXACT [UniProtKB:Q8N302] synonym: "GPATCH7" EXACT [UniProtKB:Q8N302] synonym: "VG5Q" EXACT [UniProtKB:Q8N302] xref: EMBL:AK001145 xref: EMBL:AY500994 xref: EMBL:AY500996 xref: EMBL:BC002828 xref: EMBL:BC029382 xref: EMBL:U84971 xref: HGNC:HGNC:24684 xref: UniGene:Hs.634849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057450 ! AGGF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016931 name: AGK_human def: "Acylglycerol kinase, mitochondrial precursor gene" [UniProtKB:Q53H12] synonym: "MULK" EXACT [UniProtKB:Q53H12] xref: EMBL:AC004918 xref: EMBL:AC073878 xref: EMBL:AC099547 xref: EMBL:AJ278150 xref: EMBL:AK001704 xref: EMBL:AK222769 xref: EMBL:BC009775 xref: EMBL:BC022777 xref: HGNC:HGNC:21869 xref: UniGene:Hs.699361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056362 ! AGK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016932 name: AGRP_human def: "Agouti-related protein precursor gene" [UniProtKB:O00253] synonym: "AGRT" EXACT [UniProtKB:O00253] synonym: "ART" EXACT [UniProtKB:O00253] xref: EMBL:AF281309 xref: EMBL:AF314194 xref: EMBL:BC110443 xref: EMBL:DQ374394 xref: EMBL:U88063 xref: EMBL:U89485 xref: HGNC:HGNC:330 xref: UniGene:Hs.104633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054303 ! AGRP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016933 name: AGTR1_human def: "Type-1 angiotensin II receptor gene" [UniProtKB:P30556] synonym: "AGTR1A" EXACT [UniProtKB:P30556] synonym: "AGTR1B" EXACT [UniProtKB:P30556] synonym: "AT2R1" EXACT [UniProtKB:P30556] synonym: "AT2R1B" EXACT [UniProtKB:P30556] xref: EMBL:AF245699 xref: EMBL:AY221090 xref: EMBL:BC068494 xref: EMBL:D13814 xref: EMBL:M87290 xref: EMBL:M91464 xref: EMBL:M93394 xref: EMBL:S77410 xref: EMBL:X65699 xref: EMBL:Z11162 xref: HGNC:HGNC:336 xref: UniGene:Hs.477887 xref: UniGene:Hs.705369 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055223 ! AGTR1_HUMAN relationship: codes_for CCO:B0056860 ! Q6NUP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016934 name: AGTR2_human def: "Type-2 angiotensin II receptor gene" [UniProtKB:P50052] xref: EMBL:AL732602 xref: EMBL:AY322542 xref: EMBL:AY324607 xref: EMBL:AY536522 xref: EMBL:BC095504 xref: EMBL:CR541969 xref: EMBL:L34579 xref: EMBL:U10273 xref: EMBL:U15592 xref: EMBL:U16957 xref: EMBL:U20860 xref: EMBL:U27478 xref: EMBL:X87723 xref: HGNC:HGNC:338 xref: UniGene:Hs.405348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055442 ! AGTR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016935 name: AHSP_human def: "Alpha-hemoglobin-stabilizing protein gene" [UniProtKB:Q9NZD4] synonym: "EDRF" EXACT [UniProtKB:Q9NZD4] synonym: "ERAF" EXACT [UniProtKB:Q9NZD4] xref: EMBL:AF208865 xref: EMBL:AF364517 xref: EMBL:AF485325 xref: EMBL:AY072612 xref: EMBL:BC035842 xref: HGNC:HGNC:18075 xref: UniGene:Hs.274309 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058994 ! AHSP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016936 name: AIFM2_human def: "Apoptosis-inducing factor 2 gene" [UniProtKB:Q9BRQ8] synonym: "AMID" EXACT [UniProtKB:Q9BRQ8] synonym: "PRG3" EXACT [UniProtKB:Q9BRQ8] xref: EMBL:AF337957 xref: EMBL:AF506757 xref: EMBL:AK027403 xref: EMBL:AL731540 xref: EMBL:BC006121 xref: EMBL:BC023601 xref: EMBL:BX537621 xref: HGNC:HGNC:21411 xref: UniGene:Hs.655377 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058494 ! AIFM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016937 name: AIFM3_human def: "Apoptosis-inducing factor 3 gene" [UniProtKB:Q96NN9] synonym: "AIFL" EXACT [UniProtKB:Q96NN9] xref: EMBL:AK055035 xref: EMBL:AK094844 xref: EMBL:AK126917 xref: EMBL:BC032485 xref: EMBL:CR456342 xref: HGNC:HGNC:26398 xref: UniGene:Hs.163543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058311 ! AIFM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016938 name: AIRE_human def: "Autoimmune regulator gene" [UniProtKB:O43918] synonym: "APECED" EXACT [UniProtKB:O43918] xref: EMBL:AB006682 xref: EMBL:AB006683 xref: EMBL:AB006684 xref: EMBL:AB006685 xref: EMBL:AJ009610 xref: EMBL:AP001754 xref: EMBL:Z97990 xref: HGNC:HGNC:360 xref: UniGene:Hs.129829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054531 ! AIRE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016939 name: AKAP10_human def: "A kinase anchor protein 10, mitochondrial precursor gene" [UniProtKB:O43572] xref: EMBL:AF037439 xref: EMBL:BC017055 xref: HGNC:HGNC:368 xref: UniGene:Hs.694769 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054493 ! AKA10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016940 name: AKAP11_human def: "A-kinase anchor protein 11 gene" [UniProtKB:Q9UKA4] synonym: "AKAP220" EXACT [UniProtKB:Q9UKA4] synonym: "KIAA0629" EXACT [UniProtKB:Q9UKA4] xref: EMBL:AB014529 xref: EMBL:AF176555 xref: EMBL:AK002166 xref: EMBL:AL136527 xref: HGNC:HGNC:369 xref: UniGene:Hs.105105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059189 ! AKA11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016941 name: AKAP12_human def: "A-kinase anchor protein 12 gene" [UniProtKB:Q02952] synonym: "AKAP250" EXACT [UniProtKB:Q02952] xref: EMBL:AB003476 xref: EMBL:AB210003 xref: EMBL:AF001504 xref: EMBL:AL033392 xref: EMBL:AL356535 xref: EMBL:AL590413 xref: EMBL:CR749527 xref: EMBL:M96322 xref: EMBL:U81607 xref: HGNC:HGNC:370 xref: UniGene:Hs.371240 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053806 ! A6NEC7_HUMAN relationship: codes_for CCO:B0055718 ! AKA12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016942 name: AKAP7_human def: "A-kinase anchor protein 7 isoforms alpha and beta gene" [UniProtKB:O43687] synonym: "AKAP18" EXACT [UniProtKB:O43687] xref: EMBL:AF047715 xref: EMBL:AF161075 xref: EMBL:AL136110 xref: EMBL:AL137063 xref: EMBL:BC016927 xref: EMBL:BC073847 xref: EMBL:BC094732 xref: HGNC:HGNC:377 xref: UniGene:Hs.486483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054511 ! AKA7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016943 name: AKAP3_human def: "A-kinase anchor protein 3 gene" [UniProtKB:O75969] synonym: "AKAP110" EXACT [UniProtKB:O75969] synonym: "SOB1" EXACT [UniProtKB:O75969] xref: EMBL:AF087003 xref: EMBL:AF093408 xref: EMBL:U85715 xref: HGNC:HGNC:373 xref: UniGene:Hs.98397 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054682 ! AKAP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016944 name: AKAP4_human def: "A-kinase anchor protein 4 precursor gene" [UniProtKB:Q5JQC9] synonym: "AKAP82" EXACT [UniProtKB:Q5JQC9] xref: EMBL:AF072756 xref: EMBL:AL663119 xref: EMBL:BC126250 xref: EMBL:BC126252 xref: EMBL:Y15195 xref: HGNC:HGNC:374 xref: UniGene:Hs.97633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056456 ! AKAP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016945 name: AKAP5_human def: "A-kinase anchor protein 5 gene" [UniProtKB:P24588] synonym: "AKAP79" EXACT [UniProtKB:P24588] xref: EMBL:BC057229 xref: EMBL:M90359 xref: HGNC:HGNC:375 xref: UniGene:Hs.656683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055172 ! AKAP5_HUMAN relationship: codes_for CCO:B0056905 ! Q6PG46_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016946 name: ANKDD1A_human def: "Ankyrin repeat and death domain-containing protein 1A precursor gene" [UniProtKB:Q495B1] xref: EMBL:AK075298 xref: EMBL:AK098736 xref: EMBL:BC047607 xref: EMBL:BC101273 xref: EMBL:BC101274 xref: EMBL:BC101275 xref: HGNC:HGNC:28002 xref: UniGene:Hs.207157 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056293 ! AKD1A_HUMAN relationship: codes_for CCO:B0056909 ! Q6PI29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016947 name: AKNA_human def: "AT-hook-containing transcription factor gene" [UniProtKB:Q7Z591] synonym: "KIAA1968" EXACT [UniProtKB:Q7Z591] xref: EMBL:AB075848 xref: EMBL:AF286341 xref: EMBL:AK024431 xref: EMBL:AK074040 xref: EMBL:AK126136 xref: EMBL:AK131082 xref: EMBL:AK160382 xref: EMBL:AL356796 xref: EMBL:AY703039 xref: EMBL:AY703043 xref: EMBL:AY703044 xref: EMBL:AY703045 xref: EMBL:BC042202 xref: EMBL:BC055285 xref: HGNC:HGNC:24108 xref: UniGene:Hs.494895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057176 ! AKNA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016948 name: AKAP13_human def: "A-kinase anchor protein 13 gene" [UniProtKB:Q12802] synonym: "BRX" EXACT [UniProtKB:Q12802] synonym: "HT31" EXACT [UniProtKB:Q12802] synonym: "LBC" EXACT [UniProtKB:Q12802] xref: EMBL:AB055890 xref: EMBL:AB209414 xref: EMBL:AC104046 xref: EMBL:AF126008 xref: EMBL:AF127481 xref: EMBL:AF387101 xref: EMBL:AF406992 xref: EMBL:BC050312 xref: EMBL:M90360 xref: EMBL:U03634 xref: HGNC:HGNC:371 xref: UniGene:Hs.459211 xref: UniGene:Hs.703123 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054062 ! A8MVN0_HUMAN relationship: codes_for CCO:B0055843 ! AKP13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016949 name: AKT1S1_human def: "Proline-rich AKT1 substrate 1 gene" [UniProtKB:Q96B36] synonym: "PRAS40" EXACT [UniProtKB:Q96B36] xref: EMBL:AK055511 xref: EMBL:BC000031 xref: EMBL:BC007416 xref: EMBL:BC015562 xref: EMBL:BC016043 xref: EMBL:BC051844 xref: HGNC:HGNC:28426 xref: UniGene:Hs.515542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058160 ! AKTS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016950 name: ALDH1A3_human def: "Aldehyde dehydrogenase family 1 member A3 gene" [UniProtKB:P47895] synonym: "ALDH6" EXACT [UniProtKB:P47895] xref: EMBL:BC069274 xref: EMBL:U07919 xref: HGNC:HGNC:409 xref: UniGene:Hs.459538 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055392 ! AL1A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016951 name: ALS2CR8_human def: "Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein gene" [UniProtKB:Q8N187] synonym: "CARF" EXACT [UniProtKB:Q8N187] xref: EMBL:AB053309 xref: EMBL:AB053310 xref: EMBL:AC010900 xref: EMBL:AF454946 xref: EMBL:AK025232 xref: EMBL:AL834188 xref: EMBL:AY032876 xref: EMBL:BC033777 xref: HGNC:HGNC:14435 xref: UniGene:Hs.444982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057425 ! AL2S8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016952 name: ALB_human def: "Serum albumin precursor gene" [UniProtKB:P02768] synonym: "GIG20" EXACT [UniProtKB:P02768] synonym: "GIG42" EXACT [UniProtKB:P02768] synonym: "PRO0903" EXACT [UniProtKB:P02768] synonym: "PRO1708" EXACT [UniProtKB:P02768] synonym: "PRO2044" EXACT [UniProtKB:P02768] synonym: "PRO2619" EXACT [UniProtKB:P02768] synonym: "PRO2675" EXACT [UniProtKB:P02768] synonym: "UNQ696/PRO1341" EXACT [UniProtKB:P02768] xref: EMBL:A06977 xref: EMBL:AF116645 xref: EMBL:AF118090 xref: EMBL:AF119840 xref: EMBL:AF119890 xref: EMBL:AF130077 xref: EMBL:AF190168 xref: EMBL:AF542069 xref: EMBL:AY358313 xref: EMBL:AY544124 xref: EMBL:AY550967 xref: EMBL:AY728024 xref: EMBL:BC014308 xref: EMBL:BC034023 xref: EMBL:BC036003 xref: EMBL:BC041789 xref: EMBL:CH471057 xref: EMBL:CR749331 xref: EMBL:DQ986150 xref: EMBL:EF649953 xref: EMBL:M12523 xref: EMBL:M13075 xref: EMBL:U22961 xref: EMBL:V00494 xref: EMBL:V00495 xref: HGNC:HGNC:399 xref: UniGene:Hs.418167 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054874 ! ALBU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016953 name: ALS2_human def: "Alsin gene" [UniProtKB:Q96Q42] synonym: "ALS2CR6" EXACT [UniProtKB:Q96Q42] synonym: "KIAA1563" EXACT [UniProtKB:Q96Q42] xref: EMBL:AB046783 xref: EMBL:AB053305 xref: EMBL:AB053306 xref: EMBL:AF391100 xref: EMBL:AK023024 xref: EMBL:BC029174 xref: HGNC:HGNC:443 xref: UniGene:Hs.471096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058350 ! ALS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016954 name: ALX1_human def: "ALX homeobox protein 1 gene" [UniProtKB:Q15699] synonym: "CART1" EXACT [UniProtKB:Q15699] xref: EMBL:AJ558236 xref: EMBL:AJ558237 xref: EMBL:BC010923 xref: EMBL:U31986 xref: HGNC:HGNC:1494 xref: UniGene:Hs.41683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056097 ! ALX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016955 name: ALX3_human def: "Homeobox protein aristaless-like 3 gene" [UniProtKB:O95076] xref: EMBL:AF008202 xref: EMBL:AF008203 xref: EMBL:AL160006 xref: EMBL:BC112007 xref: EMBL:BC113428 xref: EMBL:CH471122 xref: HGNC:HGNC:449 xref: UniGene:Hs.669953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054721 ! ALX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016956 name: ALX4_human def: "Homeobox protein aristaless-like 4 gene" [UniProtKB:Q9H161] synonym: "KIAA1788" EXACT [UniProtKB:Q9H161] xref: EMBL:AB058691 xref: EMBL:AF294629 xref: EMBL:AF308822 xref: EMBL:AF308823 xref: EMBL:AF308824 xref: EMBL:AF308825 xref: EMBL:AJ279074 xref: EMBL:AJ279075 xref: EMBL:AJ279076 xref: EMBL:AJ279077 xref: EMBL:AJ404888 xref: HGNC:HGNC:450 xref: UniGene:Hs.436055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058660 ! ALX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016957 name: AMBP_human def: "Protein AMBP precursor gene" [UniProtKB:P02760] synonym: "HCP" EXACT [UniProtKB:P02760] synonym: "ITIL" EXACT [UniProtKB:P02760] xref: EMBL:AK290837 xref: EMBL:AL137850 xref: EMBL:AY544123 xref: EMBL:BC041593 xref: EMBL:CH471090 xref: EMBL:M88165 xref: EMBL:M88243 xref: EMBL:M88244 xref: EMBL:M88246 xref: EMBL:M88247 xref: EMBL:M88249 xref: EMBL:X04225 xref: EMBL:X04494 xref: EMBL:X54816 xref: EMBL:X54817 xref: EMBL:X54818 xref: HGNC:HGNC:453 xref: UniGene:Hs.436911 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054872 ! AMBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016958 name: AMFR_human def: "Autocrine motility factor receptor, isoform 1 precursor gene" [UniProtKB:P26442] xref: EMBL:AF124145 xref: EMBL:BC069197 xref: EMBL:L35233 xref: EMBL:M63175 xref: HGNC:HGNC:463 xref: UniGene:Hs.295137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055191 ! AMFR1_HUMAN relationship: codes_for CCO:B0059206 ! AMFR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016959 name: AMIGO1_human def: "Amphoterin-induced protein 1 precursor gene" [UniProtKB:Q86WK6] synonym: "ALI2" EXACT [UniProtKB:Q86WK6] synonym: "AMIGO" EXACT [UniProtKB:Q86WK6] synonym: "KIAA1163" EXACT [UniProtKB:Q86WK6] xref: EMBL:AB032989 xref: EMBL:AL355145 xref: EMBL:AY237007 xref: EMBL:BC040879 xref: HGNC:HGNC:20824 xref: UniGene:Hs.12264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057275 ! AMGO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016960 name: AMIGO2_human def: "Amphoterin-induced protein 2 precursor gene" [UniProtKB:Q86SJ2] synonym: "ALI1" EXACT [UniProtKB:Q86SJ2] xref: EMBL:AB079074 xref: EMBL:AB080610 xref: EMBL:AL833007 xref: EMBL:AY237005 xref: EMBL:AY454159 xref: EMBL:BC014103 xref: EMBL:BC047595 xref: EMBL:BC095477 xref: HGNC:HGNC:24073 xref: UniGene:Hs.121520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057228 ! AMGO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016961 name: AMHR2_human def: "Anti-Muellerian hormone type-2 receptor precursor gene" [UniProtKB:Q16671] synonym: "AMHR" EXACT [UniProtKB:Q16671] xref: EMBL:AF172932 xref: EMBL:BC126316 xref: EMBL:U29700 xref: EMBL:X89013 xref: EMBL:X91156 xref: EMBL:X91157 xref: EMBL:X91158 xref: EMBL:X91159 xref: EMBL:X91160 xref: EMBL:X91161 xref: EMBL:X91162 xref: EMBL:X91163 xref: EMBL:X91164 xref: EMBL:X91165 xref: EMBL:X91166 xref: HGNC:HGNC:465 xref: UniGene:Hs.659889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030651 ! AMHR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016962 name: AMOT_human def: "Angiomotin gene" [UniProtKB:Q4VCS5] synonym: "KIAA1071" EXACT [UniProtKB:Q4VCS5] xref: EMBL:AB028994 xref: EMBL:AF286598 xref: EMBL:AY987378 xref: EMBL:BC094712 xref: HGNC:HGNC:17810 xref: UniGene:Hs.528051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056332 ! AMOT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016963 name: ENPEP_human def: "Glutamyl aminopeptidase gene" [UniProtKB:Q07075] xref: EMBL:BC094770 xref: EMBL:L12468 xref: EMBL:L14721 xref: HGNC:HGNC:3355 xref: UniGene:Hs.435765 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055781 ! AMPE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016964 name: NPPB_human def: "Natriuretic peptides B precursor gene" [UniProtKB:P16860] xref: EMBL:AL021155 xref: EMBL:BC025785 xref: EMBL:CR541976 xref: EMBL:CR542003 xref: EMBL:M25296 xref: EMBL:M31776 xref: HGNC:HGNC:7940 xref: UniGene:Hs.219140 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055059 ! ANFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016965 name: ANGPTL1_human def: "Angiopoietin-related protein 1 precursor gene" [UniProtKB:O95841] synonym: "ANG3" EXACT [UniProtKB:O95841] synonym: "ANGPT3" EXACT [UniProtKB:O95841] synonym: "ARP1" EXACT [UniProtKB:O95841] synonym: "PSEC0154" EXACT [UniProtKB:O95841] synonym: "UNQ162/PRO188" EXACT [UniProtKB:O95841] xref: EMBL:AB056476 xref: EMBL:AF107253 xref: EMBL:AL355520 xref: EMBL:AY358278 xref: EMBL:BC050640 xref: HGNC:HGNC:489 xref: UniGene:Hs.591474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054799 ! ANGL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016966 name: ANGPTL2_human def: "Angiopoietin-related protein 2 precursor gene" [UniProtKB:Q9UKU9] synonym: "ARP2" EXACT [UniProtKB:Q9UKU9] synonym: "UNQ170/PRO196" EXACT [UniProtKB:Q9UKU9] xref: EMBL:AF125175 xref: EMBL:AK074726 xref: EMBL:AL356862 xref: EMBL:AY358274 xref: EMBL:BC012368 xref: EMBL:CH471090 xref: HGNC:HGNC:490 xref: UniGene:Hs.653262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057567 ! Q8NCH7_HUMAN relationship: codes_for CCO:B0059204 ! ANGL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016967 name: ANGPTL3_human def: "Angiopoietin-related protein 3 precursor gene" [UniProtKB:Q9Y5C1] synonym: "ANGPT5" EXACT [UniProtKB:Q9Y5C1] synonym: "UNQ153/PRO179" EXACT [UniProtKB:Q9Y5C1] xref: EMBL:AF152562 xref: EMBL:AY358273 xref: EMBL:AY569015 xref: EMBL:BC058287 xref: HGNC:HGNC:491 xref: UniGene:Hs.209153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059377 ! ANGL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016968 name: ANGPTL4_human def: "Angiopoietin-related protein 4 precursor gene" [UniProtKB:Q9BY76] synonym: "ARP4" EXACT [UniProtKB:Q9BY76] synonym: "HFARP" EXACT [UniProtKB:Q9BY76] synonym: "PGAR" EXACT [UniProtKB:Q9BY76] synonym: "PP1158" EXACT [UniProtKB:Q9BY76] synonym: "PSEC0166" EXACT [UniProtKB:Q9BY76] synonym: "UNQ171/PRO197" EXACT [UniProtKB:Q9BY76] xref: EMBL:AB056477 xref: EMBL:AC136469 xref: EMBL:AF153606 xref: EMBL:AF169312 xref: EMBL:AF202636 xref: EMBL:AK222489 xref: EMBL:AK222524 xref: EMBL:AY358275 xref: EMBL:BC023647 xref: HGNC:HGNC:16039 xref: UniGene:Hs.9613 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054117 ! A8MY84_HUMAN relationship: codes_for CCO:B0058572 ! ANGL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016969 name: ANGPTL5_human def: "Angiopoietin-related protein 5 precursor gene" [UniProtKB:Q86XS5] synonym: "UNQ5795/PRO19600" EXACT [UniProtKB:Q86XS5] xref: EMBL:AY169281 xref: EMBL:AY358827 xref: EMBL:BC049170 xref: HGNC:HGNC:19705 xref: UniGene:Hs.318370 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020115 ! ANGL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016970 name: ANGPTL6_human def: "Angiopoietin-related protein 6 precursor gene" [UniProtKB:Q8NI99] synonym: "AGF" EXACT [UniProtKB:Q8NI99] synonym: "ARP5" EXACT [UniProtKB:Q8NI99] synonym: "UNQ152/PRO178" EXACT [UniProtKB:Q8NI99] xref: EMBL:AB054064 xref: EMBL:AF230330 xref: EMBL:AY358276 xref: HGNC:HGNC:23140 xref: UniGene:Hs.699819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057884 ! ANGL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016971 name: ANGPTL7_human def: "Angiopoietin-related protein 7 precursor gene" [UniProtKB:O43827] synonym: "CDT6" EXACT [UniProtKB:O43827] synonym: "UNQ313/PRO356" EXACT [UniProtKB:O43827] xref: EMBL:AJ300188 xref: EMBL:AL049653 xref: EMBL:AL391561 xref: EMBL:AY358301 xref: EMBL:BC001881 xref: EMBL:BT009802 xref: EMBL:DQ012507 xref: EMBL:Y16132 xref: HGNC:HGNC:24078 xref: UniGene:Hs.146559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054522 ! ANGL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016972 name: ANGPT1_human def: "Angiopoietin-1 precursor gene" [UniProtKB:Q15389] synonym: "KIAA0003" EXACT [UniProtKB:Q15389] xref: EMBL:AB084454 xref: EMBL:AY121504 xref: EMBL:AY124380 xref: EMBL:D13628 xref: EMBL:U83508 xref: HGNC:HGNC:484 xref: UniGene:Hs.369675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056059 ! ANGP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016973 name: ANGPT2_human def: "Angiopoietin-2 precursor gene" [UniProtKB:O15123] xref: EMBL:AB009865 xref: EMBL:AF004327 xref: EMBL:AF187858 xref: EMBL:BC126200 xref: EMBL:BC126202 xref: HGNC:HGNC:485 xref: UniGene:Hs.583870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054408 ! ANGP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016974 name: ANGPT4_human def: "Angiopoietin-4 precursor gene" [UniProtKB:Q9Y264] synonym: "ANG3" EXACT [UniProtKB:Q9Y264] synonym: "ANG4" EXACT [UniProtKB:Q9Y264] xref: EMBL:AF074332 xref: EMBL:AF113708 xref: EMBL:AL050325 xref: EMBL:AL161939 xref: EMBL:BC111976 xref: EMBL:BC111978 xref: HGNC:HGNC:487 xref: UniGene:Hs.278973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059294 ! ANGP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016975 name: ANKRD1_human def: "Ankyrin repeat domain-containing protein 1 gene" [UniProtKB:Q15327] synonym: "C193" EXACT [UniProtKB:Q15327] synonym: "CARP" EXACT [UniProtKB:Q15327] synonym: "HA1A2" EXACT [UniProtKB:Q15327] xref: EMBL:AL590622 xref: EMBL:AY903446 xref: EMBL:BC018667 xref: EMBL:X83703 xref: HGNC:HGNC:15819 xref: UniGene:Hs.448589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056058 ! ANKR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016976 name: NPR3_human def: "Atrial natriuretic peptide clearance receptor precursor gene" [UniProtKB:P17342] synonym: "ANPRC" EXACT [UniProtKB:P17342] xref: EMBL:AF025998 xref: EMBL:M59305 xref: EMBL:X52282 xref: HGNC:HGNC:7945 xref: UniGene:Hs.237028 xref: UniGene:Hs.619466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055086 ! ANPRC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016977 name: ANKRD17_human def: "Ankyrin repeat domain-containing protein 17 gene" [UniProtKB:O75179] synonym: "GTAR" EXACT [UniProtKB:O75179] synonym: "KIAA0697" EXACT [UniProtKB:O75179] xref: EMBL:AB014597 xref: EMBL:AC053527 xref: EMBL:AC095053 xref: EMBL:AC105757 xref: EMBL:AF308285 xref: EMBL:AK025859 xref: EMBL:AL831903 xref: EMBL:BC004173 xref: EMBL:BC004891 xref: EMBL:BC007747 xref: EMBL:BC019963 xref: EMBL:BC043394 xref: HGNC:HGNC:23575 xref: UniGene:Hs.601206 xref: UniGene:Hs.644997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054612 ! ANR17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016978 name: AP2S1_human def: "AP-2 complex subunit sigma-1 gene" [UniProtKB:P53680] synonym: "AP17" EXACT [UniProtKB:P53680] synonym: "CLAPS2" EXACT [UniProtKB:P53680] xref: EMBL:AJ010148 xref: EMBL:AJ010149 xref: EMBL:BC006337 xref: EMBL:X97074 xref: HGNC:HGNC:565 xref: UniGene:Hs.119591 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055510 ! AP2S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016979 name: AP3B1_human def: "AP-3 complex subunit beta-1 gene" [UniProtKB:O00203] synonym: "ADTB3A" EXACT [UniProtKB:O00203] xref: EMBL:AF247736 xref: EMBL:BC038444 xref: EMBL:BX538041 xref: EMBL:U81504 xref: EMBL:U91931 xref: HGNC:HGNC:566 xref: UniGene:Hs.532091 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054299 ! AP3B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016980 name: AP3D1_human def: "AP-3 complex subunit delta-1 gene" [UniProtKB:O14617] synonym: "PRO0039" EXACT [UniProtKB:O14617] xref: EMBL:AB208804 xref: EMBL:AC005545 xref: EMBL:AF002163 xref: EMBL:AF130042 xref: EMBL:BC010065 xref: EMBL:U91930 xref: HGNC:HGNC:568 xref: UniGene:Hs.512815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054358 ! AP3D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016981 name: AP3S1_human def: "AP-3 complex subunit sigma-1 gene" [UniProtKB:Q92572] synonym: "CLAPS3" EXACT [UniProtKB:Q92572] xref: EMBL:BC000804 xref: EMBL:CR450341 xref: EMBL:D63643 xref: EMBL:U91932 xref: EMBL:X99458 xref: HGNC:HGNC:2013 xref: UniGene:Hs.406191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058066 ! AP3S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016982 name: NUDT2_human def: "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] gene" [UniProtKB:P50583] synonym: "APAH1" EXACT [UniProtKB:P50583] xref: EMBL:AL356494 xref: EMBL:BC004926 xref: EMBL:CH471071 xref: EMBL:U30313 xref: HGNC:HGNC:8049 xref: UniGene:Hs.493767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055454 ! AP4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016983 name: APAF1_human def: "Apoptotic protease-activating factor 1 gene" [UniProtKB:O14727] synonym: "KIAA0413" EXACT [UniProtKB:O14727] xref: EMBL:AB007873 xref: EMBL:AB103079 xref: EMBL:AF013263 xref: EMBL:AF134397 xref: EMBL:AF149794 xref: EMBL:AF248734 xref: EMBL:AJ133643 xref: EMBL:AJ133644 xref: EMBL:AJ133645 xref: EMBL:AJ243003 xref: EMBL:AJ243004 xref: EMBL:AJ243005 xref: EMBL:AJ243006 xref: EMBL:AJ243007 xref: EMBL:AJ243008 xref: EMBL:AJ243009 xref: EMBL:AJ243010 xref: EMBL:AJ243011 xref: EMBL:AJ243048 xref: EMBL:AJ243107 xref: HGNC:HGNC:576 xref: UniGene:Hs.552567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054371 ! APAF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016984 name: APBA3_human def: "Amyloid beta A4 precursor protein-binding family A member 3 gene" [UniProtKB:O96018] synonym: "MINT3" EXACT [UniProtKB:O96018] synonym: "X11L2" EXACT [UniProtKB:O96018] xref: EMBL:AB021638 xref: EMBL:AC005954 xref: EMBL:AF029110 xref: EMBL:BC086306 xref: HGNC:HGNC:580 xref: UniGene:Hs.25527 xref: UniGene:Hs.465607 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016816 ! APBA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016985 name: APLN_human def: "Apelin precursor gene" [UniProtKB:Q9ULZ1] synonym: "APEL" EXACT [UniProtKB:Q9ULZ1] xref: EMBL:AB023493 xref: EMBL:AF179680 xref: EMBL:AL022162 xref: EMBL:BC021104 xref: HGNC:HGNC:16665 xref: UniGene:Hs.303084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059238 ! APEL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016986 name: APEX1_human def: "DNA-(apurinic or apyrimidinic site) lyase gene" [UniProtKB:P27695] synonym: "APE" EXACT [UniProtKB:P27695] synonym: "APEX" EXACT [UniProtKB:P27695] synonym: "APX" EXACT [UniProtKB:P27695] synonym: "HAP1" EXACT [UniProtKB:P27695] synonym: "REF1" EXACT [UniProtKB:P27695] xref: EMBL:AF488551 xref: EMBL:BC002338 xref: EMBL:BC004979 xref: EMBL:BC008145 xref: EMBL:BC019291 xref: EMBL:BT007236 xref: EMBL:D13370 xref: EMBL:D90373 xref: EMBL:M80261 xref: EMBL:M81955 xref: EMBL:M92444 xref: EMBL:M99703 xref: EMBL:S43127 xref: EMBL:U79268 xref: EMBL:X59764 xref: EMBL:X66133 xref: HGNC:HGNC:587 xref: UniGene:Hs.73722 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055194 ! APEX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016987 name: APH1A_human def: "Gamma-secretase subunit APH-1A gene" [UniProtKB:Q96BI3] synonym: "CGI-78" EXACT [UniProtKB:Q96BI3] synonym: "PSF" EXACT [UniProtKB:Q96BI3] synonym: "UNQ579/PRO1141" EXACT [UniProtKB:Q96BI3] xref: EMBL:AF151835 xref: EMBL:AF508787 xref: EMBL:AK075295 xref: EMBL:AY113698 xref: EMBL:AY113699 xref: EMBL:AY358951 xref: EMBL:BC001230 xref: EMBL:BC008732 xref: EMBL:BC009501 xref: EMBL:BC015568 xref: EMBL:BC017699 xref: EMBL:BC020590 xref: HGNC:HGNC:29509 xref: UniGene:Hs.108408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058164 ! APH1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016988 name: APH1B_human def: "Gamma-secretase subunit APH-1B gene" [UniProtKB:Q8WW43] synonym: "PSFL" EXACT [UniProtKB:Q8WW43] synonym: "UNQ688/PRO1328" EXACT [UniProtKB:Q8WW43] xref: EMBL:AF508794 xref: EMBL:AL136671 xref: EMBL:AY358698 xref: EMBL:BC020905 xref: HGNC:HGNC:24080 xref: UniGene:Hs.511703 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058000 ! APH1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016989 name: API5_human def: "Apoptosis inhibitor 5 gene" [UniProtKB:Q9BZZ5] synonym: "MIG8" EXACT [UniProtKB:Q9BZZ5] xref: EMBL:AF229253 xref: EMBL:AF229254 xref: EMBL:AY265973 xref: EMBL:AY311389 xref: EMBL:BC017709 xref: EMBL:BT007093 xref: EMBL:U83857 xref: EMBL:Y15906 xref: HGNC:HGNC:594 xref: UniGene:Hs.435771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058612 ! API5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016990 name: APLNR_human def: "Apelin receptor gene" [UniProtKB:P35414] synonym: "AGTRL1" EXACT [UniProtKB:P35414] synonym: "APJ" EXACT [UniProtKB:P35414] xref: EMBL:BC032688 xref: EMBL:U03642 xref: EMBL:X89271 xref: HGNC:HGNC:339 xref: UniGene:Hs.438311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055290 ! APJ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016991 name: APOA1_human def: "Apolipoprotein A-I precursor gene" [UniProtKB:P02647] xref: EMBL:A14829 xref: EMBL:AY422952 xref: EMBL:AY555191 xref: EMBL:BC005380 xref: EMBL:BC110286 xref: EMBL:J00098 xref: EMBL:M11791 xref: EMBL:M27875 xref: EMBL:M29068 xref: EMBL:X00566 xref: EMBL:X01038 xref: EMBL:X02162 xref: EMBL:X07496 xref: HGNC:HGNC:600 xref: UniGene:Hs.633003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028600 ! APOA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016992 name: APOA2_human def: "Apolipoprotein A-II precursor gene" [UniProtKB:P02652] xref: EMBL:AL590714 xref: EMBL:AY100524 xref: EMBL:BC005282 xref: EMBL:BT006786 xref: EMBL:M29882 xref: EMBL:X00955 xref: EMBL:X02619 xref: EMBL:X02905 xref: EMBL:X04898 xref: HGNC:HGNC:601 xref: UniGene:Hs.237658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054863 ! APOA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016993 name: APOA5_human def: "Apolipoprotein A-V precursor gene" [UniProtKB:Q6Q788] synonym: "RAP3" EXACT [UniProtKB:Q6Q788] synonym: "UNQ411/PRO773" EXACT [UniProtKB:Q6Q788] xref: EMBL:AF202889 xref: EMBL:AF202890 xref: EMBL:AY358749 xref: EMBL:AY422949 xref: EMBL:AY555191 xref: EMBL:BC101787 xref: EMBL:BC101789 xref: HGNC:HGNC:17288 xref: UniGene:Hs.283923 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056927 ! APOA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016994 name: APOC3_human def: "Apolipoprotein C-III precursor gene" [UniProtKB:P02656] xref: EMBL:AY422951 xref: EMBL:AY555191 xref: EMBL:BC027977 xref: EMBL:BC121081 xref: EMBL:J00098 xref: EMBL:M28613 xref: EMBL:M28614 xref: EMBL:M33041 xref: EMBL:M33042 xref: EMBL:M33043 xref: EMBL:V01513 xref: EMBL:X00567 xref: EMBL:X01388 xref: EMBL:X01392 xref: EMBL:X03120 xref: HGNC:HGNC:610 xref: UniGene:Hs.73849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054864 ! APOC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016995 name: APOE_human def: "Apolipoprotein E precursor gene" [UniProtKB:P02649] xref: EMBL:AB035149 xref: EMBL:AF050154 xref: EMBL:AF261279 xref: EMBL:BC003557 xref: EMBL:K00396 xref: EMBL:M10065 xref: EMBL:M12529 xref: HGNC:HGNC:613 xref: UniGene:Hs.654439 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054862 ! APOE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016996 name: APOH_human def: "Beta-2-glycoprotein 1 precursor gene" [UniProtKB:P02749] synonym: "B2G1" EXACT [UniProtKB:P02749] xref: EMBL:AY322156 xref: EMBL:BC020703 xref: EMBL:BC026283 xref: EMBL:M62839 xref: EMBL:S80305 xref: EMBL:X53595 xref: EMBL:X57847 xref: EMBL:X58100 xref: EMBL:Y11493 xref: EMBL:Y11494 xref: EMBL:Y11495 xref: EMBL:Y11496 xref: EMBL:Y11497 xref: EMBL:Y11498 xref: EMBL:Y17754 xref: HGNC:HGNC:616 xref: UniGene:Hs.445358 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054871 ! APOH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016997 name: AQP3_human def: "Aquaporin-3 gene" [UniProtKB:Q92482] xref: EMBL:AB001325 xref: EMBL:AJ493597 xref: EMBL:AL356218 xref: EMBL:BC013566 xref: EMBL:BT007199 xref: EMBL:CR541991 xref: EMBL:DQ083949 xref: HGNC:HGNC:636 xref: UniGene:Hs.234642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058057 ! AQP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016998 name: ARL2BP_human def: "ADP-ribosylation factor-like protein 2-binding protein gene" [UniProtKB:Q9Y2Y0] synonym: "BART" EXACT [UniProtKB:Q9Y2Y0] synonym: "BART1" EXACT [UniProtKB:Q9Y2Y0] xref: EMBL:AF126062 xref: EMBL:BC003087 xref: EMBL:BC094878 xref: HGNC:HGNC:17146 xref: UniGene:Hs.632873 xref: UniGene:Hs.644888 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059322 ! AR2BP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0016999 name: ADRBK1_human def: "Beta-adrenergic receptor kinase 1 gene" [UniProtKB:P25098] synonym: "BARK" EXACT [UniProtKB:P25098] synonym: "BARK1" EXACT [UniProtKB:P25098] synonym: "GRK2" EXACT [UniProtKB:P25098] xref: EMBL:BC037963 xref: EMBL:BC090863 xref: EMBL:M80776 xref: EMBL:U08435 xref: EMBL:U08436 xref: EMBL:U08437 xref: EMBL:U08438 xref: EMBL:X61157 xref: HGNC:HGNC:289 xref: UniGene:Hs.83636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055180 ! ARBK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017000 name: ADRBK2_human def: "Beta-adrenergic receptor kinase 2 gene" [UniProtKB:P35626] synonym: "BARK2" EXACT [UniProtKB:P35626] synonym: "GRK3" EXACT [UniProtKB:P35626] xref: EMBL:AL022329 xref: EMBL:X69117 xref: HGNC:HGNC:290 xref: UniGene:Hs.657494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055298 ! ARBK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017001 name: TRIM23_human def: "GTP-binding protein ARD-1 gene" [UniProtKB:P36406] synonym: "ARD1" EXACT [UniProtKB:P36406] synonym: "ARFD1" EXACT [UniProtKB:P36406] synonym: "RNF46" EXACT [UniProtKB:P36406] xref: EMBL:AF230397 xref: EMBL:AF230398 xref: EMBL:AF230399 xref: EMBL:BC022510 xref: EMBL:L04510 xref: HGNC:HGNC:660 xref: UniGene:Hs.792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055308 ! ARD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017002 name: AREG_human def: "Amphiregulin precursor gene" [UniProtKB:P15514] synonym: "SDGF" EXACT [UniProtKB:P15514] xref: EMBL:AY442340 xref: EMBL:BC009799 xref: EMBL:M30698 xref: EMBL:M30699 xref: EMBL:M30700 xref: EMBL:M30701 xref: EMBL:M30702 xref: EMBL:M30704 xref: HGNC:HGNC:651 xref: UniGene:Hs.270833 xref: UniGene:Hs.645475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055039 ! AREG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017003 name: ARF1_human def: "ADP-ribosylation factor 1 gene" [UniProtKB:P84077] xref: EMBL:AF052179 xref: EMBL:AF055002 xref: EMBL:AF493881 xref: EMBL:AL136379 xref: EMBL:BC009247 xref: EMBL:BC010429 xref: EMBL:BC011358 xref: EMBL:BT007393 xref: EMBL:M36340 xref: EMBL:M84326 xref: EMBL:M84332 xref: HGNC:HGNC:652 xref: UniGene:Hs.286221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015288 ! ARF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017004 name: ARF3_human def: "ADP-ribosylation factor 3 gene" [UniProtKB:P61204] xref: EMBL:AF493882 xref: EMBL:BC007647 xref: EMBL:BC007762 xref: EMBL:BC017565 xref: EMBL:BC028402 xref: EMBL:BT006670 xref: EMBL:M33384 xref: EMBL:M74491 xref: EMBL:M74493 xref: HGNC:HGNC:654 xref: UniGene:Hs.119177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015284 ! ARF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017005 name: ARF4_human def: "ADP-ribosylation factor 4 gene" [UniProtKB:P18085] synonym: "ARF2" EXACT [UniProtKB:P18085] xref: EMBL:AF104233 xref: EMBL:AF104234 xref: EMBL:AF104235 xref: EMBL:AF104236 xref: EMBL:AF104237 xref: EMBL:AF104238 xref: EMBL:AF493883 xref: EMBL:BC003364 xref: EMBL:BC008753 xref: EMBL:BC016325 xref: EMBL:BC022866 xref: EMBL:M36341 xref: HGNC:HGNC:655 xref: UniGene:Hs.695943 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055099 ! ARF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017006 name: ARF5_human def: "ADP-ribosylation factor 5 gene" [UniProtKB:P84085] xref: EMBL:AF493884 xref: EMBL:BC003043 xref: EMBL:BC033104 xref: EMBL:BT007087 xref: EMBL:M57567 xref: EMBL:U73002 xref: HGNC:HGNC:658 xref: UniGene:Hs.653202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055662 ! ARF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017007 name: ARF6_human def: "ADP-ribosylation factor 6 gene" [UniProtKB:P62330] xref: EMBL:AF047432 xref: EMBL:AF493885 xref: EMBL:BC002952 xref: EMBL:BC008918 xref: EMBL:M57763 xref: HGNC:HGNC:659 xref: UniGene:Hs.525330 xref: UniGene:Hs.593068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055616 ! ARF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017008 name: ARFGAP2_human def: "ADP-ribosylation factor GTPase-activating protein 2 gene" [UniProtKB:Q8N6H7] synonym: "Nbla10535" EXACT [UniProtKB:Q8N6H7] synonym: "ZNF289" EXACT [UniProtKB:Q8N6H7] xref: EMBL:AB073358 xref: EMBL:AC090589 xref: EMBL:AK027482 xref: EMBL:AL834337 xref: EMBL:BC030148 xref: HGNC:HGNC:13504 xref: UniGene:Hs.436204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054099 ! A8MXL3_HUMAN relationship: codes_for CCO:B0057489 ! ARFG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017009 name: ARFGAP3_human def: "ADP-ribosylation factor GTPase-activating protein 3 gene" [UniProtKB:Q9NP61] synonym: "ARFGAP1" EXACT [UniProtKB:Q9NP61] xref: EMBL:AF111847 xref: EMBL:AK002083 xref: EMBL:AK022768 xref: EMBL:AL049757 xref: EMBL:AL049758 xref: EMBL:AL137598 xref: EMBL:AL159143 xref: EMBL:BC005122 xref: EMBL:CR456382 xref: HGNC:HGNC:661 xref: UniGene:Hs.162877 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054172 ! B0QYV8_HUMAN relationship: codes_for CCO:B0054173 ! B0QYV9_HUMAN relationship: codes_for CCO:B0058833 ! ARFG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017010 name: ARFIP2_human def: "Arfaptin-2 gene" [UniProtKB:P53365] synonym: "POR1" EXACT [UniProtKB:P53365] xref: EMBL:BC000392 xref: EMBL:U52522 xref: EMBL:X97567 xref: HGNC:HGNC:17160 xref: UniGene:Hs.75139 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055508 ! ARFP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017011 name: ARFRP1_human def: "ADP-ribosylation factor-related protein 1 gene" [UniProtKB:Q13795] synonym: "ARP1" EXACT [UniProtKB:Q13795] xref: EMBL:AF217796 xref: EMBL:AL121845 xref: EMBL:BC092480 xref: EMBL:BC093967 xref: EMBL:BT019624 xref: EMBL:BT019663 xref: EMBL:CR456752 xref: EMBL:X91504 xref: HGNC:HGNC:662 xref: UniGene:Hs.389277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055942 ! ARFRP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017012 name: ARGFX_human def: "Arginine-fifty homeobox gene" [UniProtKB:A6NJG6] xref: EMBL:AC069239 xref: HGNC:HGNC:30146 xref: UniGene:Hs.224976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053870 ! ARGFX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017013 name: ARG2_human def: "Arginase-2, mitochondrial precursor gene" [UniProtKB:P78540] xref: EMBL:AY074489 xref: EMBL:BC001350 xref: EMBL:BC008464 xref: EMBL:BC029050 xref: EMBL:CR536550 xref: EMBL:D86724 xref: EMBL:U75667 xref: EMBL:U82256 xref: HGNC:HGNC:664 xref: UniGene:Hs.705408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055648 ! ARGI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017014 name: ARHGEF3_human def: "Rho guanine nucleotide exchange factor 3 gene" [UniProtKB:Q9NR81] xref: EMBL:AB209661 xref: EMBL:AF249744 xref: EMBL:AF433662 xref: EMBL:AK024340 xref: EMBL:AL136832 xref: EMBL:BC054345 xref: EMBL:BC068513 xref: EMBL:BC098122 xref: EMBL:BC098272 xref: EMBL:BC099715 xref: EMBL:BC104723 xref: HGNC:HGNC:683 xref: UniGene:Hs.476402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058889 ! ARHG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017015 name: ARHGEF5_human def: "Rho guanine nucleotide exchange factor 5 gene" [UniProtKB:Q12774] synonym: "TIM" EXACT [UniProtKB:Q12774] xref: EMBL:AC004534 xref: EMBL:AK160365 xref: EMBL:BC010046 xref: EMBL:BC011839 xref: EMBL:BC014555 xref: EMBL:CH471146 xref: EMBL:U02082 xref: HGNC:HGNC:13209 xref: UniGene:Hs.334 xref: UniGene:Hs.534621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055839 ! ARHG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017016 name: ARHGEF6_human def: "Rho guanine nucleotide exchange factor 6 gene" [UniProtKB:Q15052] synonym: "COOL2" EXACT [UniProtKB:Q15052] synonym: "KIAA0006" EXACT [UniProtKB:Q15052] synonym: "PIXA" EXACT [UniProtKB:Q15052] xref: EMBL:AF207831 xref: EMBL:AK291742 xref: EMBL:AL135783 xref: EMBL:AL683813 xref: EMBL:BC039856 xref: EMBL:BC043505 xref: EMBL:BX537390 xref: EMBL:CH471150 xref: EMBL:D13631 xref: EMBL:D25304 xref: HGNC:HGNC:685 xref: UniGene:Hs.522795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054235 ! B1AL37_HUMAN relationship: codes_for CCO:B0056039 ! ARHG6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017017 name: ARHGEF7_human def: "Rho guanine nucleotide exchange factor 7 gene" [UniProtKB:Q14155] synonym: "COOL1" EXACT [UniProtKB:Q14155] synonym: "KIAA0142" EXACT [UniProtKB:Q14155] synonym: "Nbla10314" EXACT [UniProtKB:Q14155] synonym: "P85SPR" EXACT [UniProtKB:Q14155] synonym: "PAK3BP" EXACT [UniProtKB:Q14155] synonym: "PIXB" EXACT [UniProtKB:Q14155] xref: EMBL:AB075521 xref: EMBL:AB177849 xref: EMBL:AL139086 xref: EMBL:AL390754 xref: EMBL:AL834228 xref: EMBL:BC033905 xref: EMBL:BC050521 xref: EMBL:BC060776 xref: EMBL:CH471085 xref: EMBL:D63476 xref: HGNC:HGNC:15607 xref: UniGene:Hs.508738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054239 ! B1ALK7_HUMAN relationship: codes_for CCO:B0055966 ! ARHG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017018 name: NET1_human def: "Neuroepithelial cell-transforming gene 1 protein gene" [UniProtKB:Q7Z628] synonym: "ARHGEF8" EXACT [UniProtKB:Q7Z628] xref: EMBL:AJ010046 xref: EMBL:AL732437 xref: EMBL:BC010285 xref: EMBL:BC053553 xref: EMBL:S82401 xref: EMBL:U02081 xref: HGNC:HGNC:14592 xref: UniGene:Hs.25155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056533 ! Q5SQI6_HUMAN relationship: codes_for CCO:B0057190 ! ARHG8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017019 name: ARHGEF10_human def: "Rho guanine nucleotide exchange factor 10 gene" [UniProtKB:O15013] synonym: "KIAA0294" EXACT [UniProtKB:O15013] xref: EMBL:AB002292 xref: EMBL:AC019257 xref: EMBL:AF009205 xref: EMBL:BC036809 xref: EMBL:BC040474 xref: EMBL:CH471181 xref: EMBL:CR749570 xref: HGNC:HGNC:14103 xref: UniGene:Hs.98594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054005 ! A8MS93_HUMAN relationship: codes_for CCO:B0054397 ! ARHGA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017020 name: ARHGEF11_human def: "Rho guanine nucleotide exchange factor 11 gene" [UniProtKB:O15085] synonym: "KIAA0380" EXACT [UniProtKB:O15085] xref: EMBL:AB002378 xref: EMBL:AL157713 xref: EMBL:AL356104 xref: EMBL:BC057394 xref: HGNC:HGNC:14580 xref: UniGene:Hs.516954 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053822 ! A6NFK4_HUMAN relationship: codes_for CCO:B0054404 ! ARHGB_HUMAN relationship: codes_for CCO:B0056903 ! Q6PFW2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017021 name: ARHGEF12_human def: "Rho guanine nucleotide exchange factor 12 gene" [UniProtKB:Q9NZN5] synonym: "KIAA0382" EXACT [UniProtKB:Q9NZN5] synonym: "LARG" EXACT [UniProtKB:Q9NZN5] xref: EMBL:AB002380 xref: EMBL:AF180681 xref: EMBL:BC063117 xref: HGNC:HGNC:14193 xref: UniGene:Hs.24598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059006 ! ARHGC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017022 name: ARHGEF16_human def: "Rho guanine nucleotide exchange factor 16 gene" [UniProtKB:Q5VV41] synonym: "NBR" EXACT [UniProtKB:Q5VV41] xref: EMBL:AL512413 xref: EMBL:BC002681 xref: EMBL:BC051838 xref: EMBL:BT007270 xref: EMBL:D89016 xref: HGNC:HGNC:15515 xref: UniGene:Hs.87435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054183 ! B0QZD3_HUMAN relationship: codes_for CCO:B0054184 ! B0QZD4_HUMAN relationship: codes_for CCO:B0056657 ! ARHGG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017023 name: ARHGEF17_human def: "Rho guanine nucleotide exchange factor 17 gene" [UniProtKB:Q96PE2] synonym: "KIAA0337" EXACT [UniProtKB:Q96PE2] synonym: "TEM4" EXACT [UniProtKB:Q96PE2] xref: EMBL:AB002335 xref: EMBL:AF378754 xref: EMBL:AK074500 xref: EMBL:BC050031 xref: HGNC:HGNC:21726 xref: UniGene:Hs.533719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058330 ! ARHGH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017024 name: ARHGEF18_human def: "Rho guanine nucleotide exchange factor 18 gene" [UniProtKB:Q6ZSZ5] synonym: "KIAA0521" EXACT [UniProtKB:Q6ZSZ5] xref: EMBL:AB011093 xref: EMBL:AK127045 xref: EMBL:BC077721 xref: HGNC:HGNC:17090 xref: UniGene:Hs.465761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057060 ! ARHGI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017025 name: ARHGEF19_human def: "Rho guanine nucleotide exchange factor 19 gene" [UniProtKB:Q8IW93] xref: EMBL:AK091281 xref: EMBL:AL109627 xref: EMBL:BC012982 xref: EMBL:BC040640 xref: HGNC:HGNC:26604 xref: UniGene:Hs.591532 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056615 ! Q5TEV0_HUMAN relationship: codes_for CCO:B0056616 ! Q5TEV1_HUMAN relationship: codes_for CCO:B0057355 ! ARHGJ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017026 name: LDLRAP1_human def: "Low density lipoprotein receptor adapter protein 1 gene" [UniProtKB:Q5SW96] synonym: "ARH" EXACT [UniProtKB:Q5SW96] xref: EMBL:AL117654 xref: EMBL:AL606491 xref: EMBL:AY389348 xref: EMBL:BC029770 xref: EMBL:BX572623 xref: HGNC:HGNC:18640 xref: UniGene:Hs.590911 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056547 ! ARH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017027 name: ARID1B_human def: "AT-rich interactive domain-containing protein 1B gene" [UniProtKB:Q8NFD5] synonym: "DAN15" EXACT [UniProtKB:Q8NFD5] synonym: "KIAA1235" EXACT [UniProtKB:Q8NFD5] synonym: "OSA2" EXACT [UniProtKB:Q8NFD5] xref: EMBL:AB033061 xref: EMBL:AF253515 xref: EMBL:AF259792 xref: EMBL:AF468300 xref: EMBL:AF521671 xref: EMBL:AJ001216 xref: EMBL:AL049820 xref: EMBL:AL162578 xref: EMBL:AL355297 xref: EMBL:AL591545 xref: EMBL:Y08266 xref: HGNC:HGNC:18040 xref: UniGene:Hs.291587 xref: UniGene:Hs.603283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057599 ! ARI1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017028 name: ARID3A_human def: "AT-rich interactive domain-containing protein 3A gene" [UniProtKB:Q99856] synonym: "DRIL1" EXACT [UniProtKB:Q99856] synonym: "DRIL3" EXACT [UniProtKB:Q99856] synonym: "DRX" EXACT [UniProtKB:Q99856] synonym: "E2FBP1" EXACT [UniProtKB:Q99856] xref: EMBL:AC005379 xref: EMBL:AC005391 xref: EMBL:AF039844 xref: EMBL:AF039845 xref: EMBL:AF039846 xref: EMBL:AF039847 xref: EMBL:AF039848 xref: EMBL:AF039849 xref: EMBL:AF039850 xref: EMBL:AY152547 xref: EMBL:AY845638 xref: EMBL:BC033163 xref: EMBL:BC060828 xref: EMBL:U88047 xref: HGNC:HGNC:3031 xref: UniGene:Hs.501296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058459 ! ARI3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017029 name: ARID3B_human def: "AT-rich interactive domain-containing protein 3B gene" [UniProtKB:Q8IVW6] synonym: "BDP" EXACT [UniProtKB:Q8IVW6] synonym: "DRIL2" EXACT [UniProtKB:Q8IVW6] xref: EMBL:AB208830 xref: EMBL:AF116846 xref: EMBL:BC041792 xref: EMBL:BC060824 xref: HGNC:HGNC:14350 xref: UniGene:Hs.655532 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057349 ! ARI3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017030 name: ARID3C_human def: "AT-rich interactive domain-containing protein 3C gene" [UniProtKB:A6NKF2] xref: EMBL:AL450283 xref: HGNC:HGNC:21209 xref: UniGene:Hs.534549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053883 ! ARI3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017031 name: ARID5A_human def: "AT-rich interactive domain-containing protein 5A gene" [UniProtKB:Q03989] synonym: "MRF1" EXACT [UniProtKB:Q03989] xref: EMBL:BC067301 xref: EMBL:M62324 xref: HGNC:HGNC:17361 xref: UniGene:Hs.920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055730 ! ARI5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017032 name: ARL10_human def: "ADP-ribosylation factor-like protein 10 gene" [UniProtKB:Q8N8L6] synonym: "ARL10A" EXACT [UniProtKB:Q8N8L6] xref: EMBL:AK096568 xref: EMBL:BK001673 xref: HGNC:HGNC:22042 xref: UniGene:Hs.424552 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057524 ! ARL10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017033 name: ARL11_human def: "ADP-ribosylation factor-like protein 11 gene" [UniProtKB:Q969Q4] synonym: "ARLTS1" EXACT [UniProtKB:Q969Q4] xref: EMBL:AF441378 xref: EMBL:AK091249 xref: EMBL:AL135901 xref: EMBL:BC013150 xref: HGNC:HGNC:24046 xref: UniGene:Hs.558599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058138 ! ARL11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017034 name: ARL14_human def: "ADP-ribosylation factor-like protein 14 gene" [UniProtKB:Q8N4G2] synonym: "ARF7" EXACT [UniProtKB:Q8N4G2] xref: EMBL:AK026248 xref: EMBL:BC034354 xref: HGNC:HGNC:22974 xref: UniGene:Hs.287702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057466 ! ARL14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017035 name: ARL2_human def: "ADP-ribosylation factor-like protein 2 gene" [UniProtKB:P36404] xref: EMBL:AF493888 xref: EMBL:BC002530 xref: EMBL:L13687 xref: HGNC:HGNC:693 xref: UniGene:Hs.502836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055307 ! ARL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017036 name: ARL4A_human def: "ADP-ribosylation factor-like protein 4A gene" [UniProtKB:P40617] synonym: "ARL4" EXACT [UniProtKB:P40617] xref: EMBL:AF493890 xref: EMBL:BC001111 xref: EMBL:BC003027 xref: EMBL:BC039123 xref: EMBL:U73960 xref: HGNC:HGNC:695 xref: UniGene:Hs.245540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055331 ! ARL4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017037 name: ARL5A_human def: "ADP-ribosylation factor-like protein 5A gene" [UniProtKB:Q9Y689] synonym: "ARFLP5" EXACT [UniProtKB:Q9Y689] synonym: "ARL5" EXACT [UniProtKB:Q9Y689] xref: EMBL:AF087889 xref: EMBL:AF100740 xref: EMBL:AF493891 xref: EMBL:BC001254 xref: EMBL:BT009829 xref: HGNC:HGNC:696 xref: UniGene:Hs.470233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059399 ! ARL5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017038 name: ARL5B_human def: "ADP-ribosylation factor-like protein 5B gene" [UniProtKB:Q96KC2] synonym: "ARL8" EXACT [UniProtKB:Q96KC2] xref: EMBL:AF494061 xref: EMBL:AK027275 xref: EMBL:BC024163 xref: HGNC:HGNC:23052 xref: UniGene:Hs.25362 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058257 ! ARL5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017039 name: ARL5C_human def: "Putative ADP-ribosylation factor-like protein 5C gene" [UniProtKB:A6NH57] synonym: "ARL12" EXACT [UniProtKB:A6NH57] xref: EMBL:AC004408 xref: HGNC:HGNC:31111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053840 ! ARL5C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017040 name: ARL6_human def: "ADP-ribosylation factor-like protein 6 gene" [UniProtKB:Q9H0F7] xref: EMBL:AL136815 xref: EMBL:BC024239 xref: HGNC:HGNC:13210 xref: UniGene:Hs.373801 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058652 ! ARL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017041 name: ARL8A_human def: "ADP-ribosylation factor-like protein 8A gene" [UniProtKB:Q96BM9] synonym: "ARL10B" EXACT [UniProtKB:Q96BM9] synonym: "GIE2" EXACT [UniProtKB:Q96BM9] xref: EMBL:AB118752 xref: EMBL:AL592300 xref: EMBL:BC015408 xref: HGNC:HGNC:25192 xref: UniGene:Hs.497399 xref: UniGene:Hs.604697 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058166 ! ARL8A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017042 name: ARL9_human def: "ADP-ribosylation factor-like protein 9 gene" [UniProtKB:Q6T311] xref: EMBL:AY439003 xref: HGNC:HGNC:23592 xref: UniGene:Hs.444449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056945 ! ARL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017043 name: ARMC10_human def: "Armadillo repeat-containing protein 10 gene" [UniProtKB:Q8N2F6] synonym: "PSEC0198" EXACT [UniProtKB:Q8N2F6] synonym: "SVH" EXACT [UniProtKB:Q8N2F6] xref: EMBL:AC007683 xref: EMBL:AC073127 xref: EMBL:AC108167 xref: EMBL:AK075500 xref: EMBL:AK291818 xref: EMBL:AY150851 xref: EMBL:AY150852 xref: EMBL:AY150853 xref: EMBL:AY150854 xref: EMBL:BC003586 xref: HGNC:HGNC:21706 xref: UniGene:Hs.287412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057443 ! ARM10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017044 name: ARMS_human def: "Ankyrin repeat-rich membrane spanning protein gene" [UniProtKB:Q9ULH0] synonym: "KIAA1250" EXACT [UniProtKB:Q9ULH0] synonym: "KIDINS220" EXACT [UniProtKB:Q9ULH0] xref: EMBL:AB033076 xref: EMBL:AK022873 xref: EMBL:AK023926 xref: EMBL:AL133620 xref: EMBL:AL137553 xref: EMBL:BC094714 xref: EMBL:BC130610 xref: EMBL:BX640878 xref: UniGene:Hs.9873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059224 ! ARMS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017045 name: ARP11_human def: "Actin-related protein 11 precursor gene" [UniProtKB:Q9C0K3] xref: EMBL:AB039791 xref: EMBL:BX640643 xref: UniGene:Hs.664579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058623 ! ARP11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017046 name: ARPP19_human def: "cAMP-regulated phosphoprotein 19 gene" [UniProtKB:P56211] xref: EMBL:AF084555 xref: EMBL:AJ223091 xref: EMBL:AL833077 xref: EMBL:BC003418 xref: EMBL:BC100015 xref: EMBL:CR457132 xref: UniGene:Hs.512908 xref: UniGene:Hs.639038 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055542 ! ARP19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017047 name: ARPC5L_human def: "Actin-related protein 2/3 complex subunit 5-like protein gene" [UniProtKB:Q9BPX5] xref: EMBL:AF087842 xref: EMBL:AL354928 xref: EMBL:BC000018 xref: EMBL:BC000798 xref: EMBL:BC002418 xref: HGNC:HGNC:23366 xref: UniGene:Hs.132499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058471 ! ARP5L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017048 name: ARPC5_human def: "Actin-related protein 2/3 complex subunit 5 gene" [UniProtKB:O15511] synonym: "ARC16" EXACT [UniProtKB:O15511] xref: EMBL:AF006088 xref: EMBL:AF017807 xref: EMBL:AL137800 xref: EMBL:BC057237 xref: EMBL:CH471067 xref: HGNC:HGNC:708 xref: UniGene:Hs.518609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054238 ! B1ALC0_HUMAN relationship: codes_for CCO:B0054441 ! ARPC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017049 name: ARRB1_human def: "Beta-arrestin-1 gene" [UniProtKB:P49407] synonym: "ARR1" EXACT [UniProtKB:P49407] xref: EMBL:AF084040 xref: EMBL:AF084940 xref: EMBL:BC003636 xref: EMBL:DQ314865 xref: EMBL:L04685 xref: HGNC:HGNC:711 xref: UniGene:Hs.503284 xref: UniGene:Hs.625320 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055424 ! ARRB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017050 name: ARRB2_human def: "Beta-arrestin-2 gene" [UniProtKB:P32121] synonym: "ARB2" EXACT [UniProtKB:P32121] synonym: "ARR2" EXACT [UniProtKB:P32121] xref: EMBL:AF106941 xref: EMBL:AK097542 xref: EMBL:BC007427 xref: EMBL:BC067368 xref: EMBL:CR450310 xref: EMBL:DQ314866 xref: EMBL:DQ664180 xref: EMBL:Z11501 xref: HGNC:HGNC:712 xref: UniGene:Hs.435811 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055250 ! ARRB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017051 name: ARR3_human def: "Arrestin-C gene" [UniProtKB:P36575] synonym: "ARRX" EXACT [UniProtKB:P36575] synonym: "CAR" EXACT [UniProtKB:P36575] xref: EMBL:AF033105 xref: EMBL:AF076497 xref: EMBL:AF076498 xref: EMBL:AF076499 xref: EMBL:AF076500 xref: EMBL:AF076501 xref: EMBL:AF076502 xref: EMBL:AF076503 xref: EMBL:AF076504 xref: EMBL:AF076505 xref: EMBL:AF076506 xref: EMBL:AF076507 xref: EMBL:AF076508 xref: EMBL:AF076509 xref: EMBL:AF076510 xref: EMBL:AF076511 xref: EMBL:AF076512 xref: EMBL:AL357752 xref: EMBL:BC012096 xref: EMBL:CR456849 xref: EMBL:U03626 xref: HGNC:HGNC:710 xref: UniGene:Hs.308 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055311 ! ARRC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017052 name: SAG_human def: "S-arrestin gene" [UniProtKB:P10523] xref: EMBL:AC013726 xref: EMBL:U70962 xref: EMBL:U70963 xref: EMBL:U70964 xref: EMBL:U70965 xref: EMBL:U70966 xref: EMBL:U70967 xref: EMBL:U70968 xref: EMBL:U70969 xref: EMBL:U70970 xref: EMBL:U70971 xref: EMBL:U70972 xref: EMBL:U70973 xref: EMBL:U70974 xref: EMBL:U70975 xref: EMBL:U70976 xref: EMBL:X12453 xref: HGNC:HGNC:10521 xref: UniGene:Hs.32721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054974 ! ARRS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017053 name: ARTN_human def: "Artemin precursor gene" [UniProtKB:Q5T4W7] synonym: "EVN" EXACT [UniProtKB:Q5T4W7] xref: EMBL:AF109401 xref: EMBL:AF115765 xref: EMBL:AF120274 xref: EMBL:AJ245628 xref: EMBL:AL357079 xref: EMBL:BC062375 xref: HGNC:HGNC:727 xref: UniGene:Hs.632404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056578 ! ARTN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017054 name: ARX_human def: "Homeobox protein ARX gene" [UniProtKB:Q96QS3] xref: EMBL:AY038071 xref: HGNC:HGNC:18060 xref: UniGene:Hs.300304 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058357 ! ARX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017055 name: C20orf74_human def: "250 kDa substrate of Akt gene" [UniProtKB:Q2PPJ7] synonym: "KIAA1272" EXACT [UniProtKB:Q2PPJ7] xref: EMBL:AB033098 xref: EMBL:AK022881 xref: EMBL:AL078634 xref: EMBL:AL121896 xref: EMBL:AL157718 xref: EMBL:AL161658 xref: EMBL:BC013749 xref: EMBL:DQ310704 xref: HGNC:HGNC:16207 xref: UniGene:Hs.472285 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054009 ! A8MSM5_HUMAN relationship: codes_for CCO:B0056222 ! AS250_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017056 name: ASAH2_human def: "Neutral ceramidase gene" [UniProtKB:Q9NR71] synonym: "HNAC1" EXACT [UniProtKB:Q9NR71] xref: EMBL:AF250847 xref: EMBL:AF449759 xref: EMBL:AL450382 xref: EMBL:AL589794 xref: EMBL:AL954360 xref: EMBL:AY049008 xref: EMBL:BC107105 xref: HGNC:HGNC:18860 xref: UniGene:Hs.512645 xref: UniGene:Hs.537110 xref: UniGene:Hs.659820 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058888 ! ASAH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017057 name: ASB10_human def: "Ankyrin repeat and SOCS box protein 10 gene" [UniProtKB:Q8WXI3] xref: EMBL:AF417920 xref: EMBL:BC126351 xref: HGNC:HGNC:17185 xref: UniGene:Hs.647081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058023 ! ASB10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017058 name: ASB11_human def: "Ankyrin repeat and SOCS box protein 11 gene" [UniProtKB:Q8WXH4] xref: EMBL:AF425642 xref: EMBL:BC069340 xref: EMBL:BC103874 xref: EMBL:BC103875 xref: HGNC:HGNC:17186 xref: UniGene:Hs.352183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058019 ! ASB11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017059 name: ASB12_human def: "Ankyrin repeat and SOCS box protein 12 gene" [UniProtKB:Q8WXK4] xref: EMBL:AF403030 xref: EMBL:AL356317 xref: EMBL:BC069436 xref: EMBL:BC069555 xref: EMBL:BC093883 xref: EMBL:BC104946 xref: HGNC:HGNC:19763 xref: UniGene:Hs.56281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058030 ! ASB12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017060 name: ASB13_human def: "Ankyrin repeat and SOCS box protein 13 gene" [UniProtKB:Q8WXK3] xref: EMBL:AF403031 xref: EMBL:AK023196 xref: EMBL:AL365356 xref: EMBL:BC012056 xref: EMBL:CR457302 xref: HGNC:HGNC:19765 xref: UniGene:Hs.445899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058029 ! ASB13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017061 name: ASB15_human def: "Ankyrin repeat and SOCS box protein 15 gene" [UniProtKB:Q8WXK1] xref: EMBL:AF403033 xref: EMBL:AK125360 xref: HGNC:HGNC:19767 xref: UniGene:Hs.83916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058027 ! ASB15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017062 name: ASB16_human def: "Ankyrin repeat and SOCS box protein 16 gene" [UniProtKB:Q96NS5] xref: EMBL:AF403034 xref: EMBL:AK054727 xref: EMBL:BC075088 xref: HGNC:HGNC:19768 xref: UniGene:Hs.534517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058312 ! ASB16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017063 name: ASB17_human def: "Ankyrin repeat and SOCS box protein 17 gene" [UniProtKB:Q8WXJ9] xref: EMBL:AF403035 xref: EMBL:AF429968 xref: EMBL:AK098606 xref: EMBL:BC036573 xref: HGNC:HGNC:19769 xref: UniGene:Hs.125423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058026 ! ASB17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017064 name: ASB18_human def: "Ankyrin repeat and SOCS box-containing protein 18 gene" [UniProtKB:Q6ZVZ8] xref: EMBL:AC019068 xref: EMBL:AC079135 xref: EMBL:AK123854 xref: HGNC:HGNC:19770 xref: UniGene:Hs.531288 xref: UniGene:Hs.639909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057087 ! ASB18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017065 name: ASB1_human def: "Ankyrin repeat and SOCS box protein 1 gene" [UniProtKB:Q9Y576] synonym: "KIAA1146" EXACT [UniProtKB:Q9Y576] xref: EMBL:AB032972 xref: EMBL:AC016999 xref: EMBL:AF156777 xref: EMBL:BC014528 xref: HGNC:HGNC:16011 xref: UniGene:Hs.516788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059373 ! ASB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017066 name: ASB2_human def: "Ankyrin repeat and SOCS box protein 2 gene" [UniProtKB:Q96Q27] xref: EMBL:AB056723 xref: EMBL:AF159164 xref: EMBL:AJ251238 xref: EMBL:AL137735 xref: EMBL:BC032354 xref: HGNC:HGNC:16012 xref: UniGene:Hs.510327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058349 ! ASB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017067 name: ASB3_human def: "Ankyrin repeat and SOCS box protein 3 gene" [UniProtKB:Q9Y575] xref: EMBL:AC008064 xref: EMBL:AF156778 xref: EMBL:AK000985 xref: EMBL:AK001283 xref: EMBL:BC006488 xref: EMBL:BC009569 xref: EMBL:BC110915 xref: HGNC:HGNC:16013 xref: UniGene:Hs.40763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056225 ! Q2TAI4_HUMAN relationship: codes_for CCO:B0056367 ! Q53TN0_HUMAN relationship: codes_for CCO:B0059372 ! ASB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017068 name: ASB4_human def: "Ankyrin repeat and SOCS box protein 4 gene" [UniProtKB:Q9Y574] xref: EMBL:AC003079 xref: EMBL:AF156779 xref: HGNC:HGNC:16009 xref: UniGene:Hs.666357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059371 ! ASB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017069 name: ASB5_human def: "Ankyrin repeat and SOCS box protein 5 gene" [UniProtKB:Q8WWX0] xref: EMBL:AY057053 xref: EMBL:BC065710 xref: HGNC:HGNC:17180 xref: UniGene:Hs.591712 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058007 ! ASB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017070 name: ASB6_human def: "Ankyrin repeat and SOCS box protein 6 gene" [UniProtKB:Q9NWX5] xref: EMBL:AK000555 xref: EMBL:AK023004 xref: EMBL:BC065913 xref: HGNC:HGNC:17181 xref: UniGene:Hs.125037 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058943 ! ASB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017071 name: ASB7_human def: "Ankyrin repeat and SOCS box protein 7 gene" [UniProtKB:Q9H672] xref: EMBL:AF451994 xref: EMBL:AK026204 xref: HGNC:HGNC:17182 xref: UniGene:Hs.31845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058734 ! ASB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017072 name: ASB8_human def: "Ankyrin repeat and SOCS box protein 8 gene" [UniProtKB:Q9H765] synonym: "PP14212" EXACT [UniProtKB:Q9H765] xref: EMBL:AF464877 xref: EMBL:AK024908 xref: EMBL:BC001321 xref: HGNC:HGNC:17183 xref: UniGene:Hs.432699 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058738 ! ASB8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017073 name: ASB9_human def: "Ankyrin repeat and SOCS box protein 9 gene" [UniProtKB:Q96DX5] xref: EMBL:AK000643 xref: EMBL:AL080091 xref: EMBL:BC013172 xref: HGNC:HGNC:17184 xref: UniGene:Hs.19404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058199 ! ASB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017074 name: ASCC1_human def: "Activating signal cointegrator 1 complex subunit 1 gene" [UniProtKB:Q8N9N2] synonym: "CGI-18" EXACT [UniProtKB:Q8N9N2] xref: EMBL:AC022392 xref: EMBL:AF132952 xref: EMBL:AK023436 xref: EMBL:AK094170 xref: EMBL:AL607035 xref: EMBL:AY013290 xref: EMBL:BC012291 xref: EMBL:CH471083 xref: HGNC:HGNC:24268 xref: UniGene:Hs.500007 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057540 ! ASCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017075 name: ASCL1_human def: "Achaete-scute homolog 1 gene" [UniProtKB:P50553] synonym: "ASH1" EXACT [UniProtKB:P50553] xref: EMBL:BC001638 xref: EMBL:BC002341 xref: EMBL:BC003134 xref: EMBL:BC004425 xref: EMBL:BC031299 xref: EMBL:L08424 xref: HGNC:HGNC:738 xref: UniGene:Hs.705375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055453 ! ASCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017076 name: ASCL2_human def: "Achaete-scute homolog 2 gene" [UniProtKB:Q99929] xref: EMBL:AF442769 xref: EMBL:S82817 xref: EMBL:U77629 xref: HGNC:HGNC:739 xref: UniGene:Hs.152475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058461 ! ASCL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017077 name: ASCL3_human def: "Achaete-scute homolog 3 gene" [UniProtKB:Q9NQ33] synonym: "HASH3" EXACT [UniProtKB:Q9NQ33] synonym: "SGN1" EXACT [UniProtKB:Q9NQ33] xref: EMBL:AB046450 xref: EMBL:AJ400877 xref: HGNC:HGNC:740 xref: UniGene:Hs.501852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058860 ! ASCL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017078 name: ASCL4_human def: "Achaete-scute homolog 4 gene" [UniProtKB:Q6XD76] synonym: "HASH4" EXACT [UniProtKB:Q6XD76] xref: EMBL:AY238895 xref: EMBL:BC128211 xref: EMBL:BC128212 xref: EMBL:BK000275 xref: HGNC:HGNC:24311 xref: UniGene:Hs.149910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056971 ! ASCL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017079 name: ASCL5_human def: "Achaete-scute homolog 5 gene" [UniProtKB:Q7RTU5] xref: EMBL:AL139159 xref: EMBL:BK000139 xref: HGNC:HGNC:33169 xref: UniGene:Hs.632474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057136 ! ASCL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017080 name: ASF1B_human def: "Histone chaperone ASF1B gene" [UniProtKB:Q9NVP2] xref: EMBL:AB104486 xref: EMBL:AF279307 xref: EMBL:AK001288 xref: EMBL:AK001466 xref: EMBL:AK223080 xref: EMBL:BC007726 xref: EMBL:BC010014 xref: EMBL:BC036521 xref: EMBL:CR457235 xref: HGNC:HGNC:20996 xref: UniGene:Hs.26516 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058932 ! ASF1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017081 name: ASGR2_human def: "Asialoglycoprotein receptor 2 gene" [UniProtKB:P07307] xref: EMBL:BC017251 xref: EMBL:M11025 xref: EMBL:U97197 xref: EMBL:X55283 xref: HGNC:HGNC:743 xref: UniGene:Hs.654440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019143 ! ASGR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017082 name: ASH1L_human def: "Probable histone-lysine N-methyltransferase ASH1L gene" [UniProtKB:Q9NR48] synonym: "KIAA1420" EXACT [UniProtKB:Q9NR48] synonym: "KMT2H" EXACT [UniProtKB:Q9NR48] xref: EMBL:AB037841 xref: EMBL:AB209068 xref: EMBL:AF257305 xref: EMBL:AL139410 xref: EMBL:AL353807 xref: HGNC:HGNC:19088 xref: UniGene:Hs.491060 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058886 ! ASH1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017083 name: ASIP_human def: "Agouti-signaling protein precursor gene" [UniProtKB:P42127] synonym: "AGTI" EXACT [UniProtKB:P42127] synonym: "AGTIL" EXACT [UniProtKB:P42127] synonym: "ASP" EXACT [UniProtKB:P42127] xref: EMBL:AL035458 xref: EMBL:BC104238 xref: EMBL:BC104239 xref: EMBL:L37019 xref: EMBL:U12770 xref: EMBL:U12774 xref: EMBL:U12775 xref: HGNC:HGNC:745 xref: UniGene:Hs.659995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055347 ! ASIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017084 name: SMPD1_human def: "Sphingomyelin phosphodiesterase precursor gene" [UniProtKB:P17405] synonym: "ASM" EXACT [UniProtKB:P17405] xref: EMBL:M59916 xref: EMBL:M59917 xref: EMBL:M81780 xref: EMBL:X52678 xref: EMBL:X52679 xref: EMBL:X59960 xref: EMBL:X63600 xref: HGNC:HGNC:11120 xref: UniGene:Hs.498173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055087 ! ASM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017085 name: ASXL1_human def: "Putative Polycomb group protein ASXL1 gene" [UniProtKB:Q8IXJ9] synonym: "KIAA0978" EXACT [UniProtKB:Q8IXJ9] xref: EMBL:AB023195 xref: EMBL:AJ438952 xref: EMBL:AL034550 xref: EMBL:AL117518 xref: EMBL:AL117647 xref: EMBL:AL121583 xref: EMBL:BC033284 xref: HGNC:HGNC:18318 xref: UniGene:Hs.374043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057379 ! ASXL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017086 name: ASXL2_human def: "Putative Polycomb group protein ASXL2 gene" [UniProtKB:Q76L83] synonym: "ASXH2" EXACT [UniProtKB:Q76L83] synonym: "KIAA1685" EXACT [UniProtKB:Q76L83] xref: EMBL:AB051472 xref: EMBL:AB084279 xref: EMBL:AB084281 xref: EMBL:AC010150 xref: EMBL:AK001760 xref: EMBL:BC042999 xref: EMBL:CR933613 xref: HGNC:HGNC:23805 xref: UniGene:Hs.700650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057105 ! ASXL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017087 name: ASXL3_human def: "Putative Polycomb group protein ASXL3 gene" [UniProtKB:Q9C0F0] synonym: "KIAA1713" EXACT [UniProtKB:Q9C0F0] xref: EMBL:AB051500 xref: EMBL:AC010798 xref: EMBL:AC023192 xref: EMBL:AC090989 xref: EMBL:AK056450 xref: EMBL:AK131454 xref: EMBL:AL133050 xref: HGNC:HGNC:29357 xref: UniGene:Hs.464876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058617 ! ASXL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017088 name: ASZ1_human def: "Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 gene" [UniProtKB:Q8WWH4] synonym: "ALP1" EXACT [UniProtKB:Q8WWH4] synonym: "ANKL1" EXACT [UniProtKB:Q8WWH4] synonym: "C7orf7" EXACT [UniProtKB:Q8WWH4] synonym: "GASZ" EXACT [UniProtKB:Q8WWH4] xref: EMBL:AF461259 xref: EMBL:AK093445 xref: EMBL:BC126186 xref: EMBL:BC126188 xref: HGNC:HGNC:1350 xref: UniGene:Hs.352412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058004 ! ASZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017089 name: ATP10A_human def: "Probable phospholipid-transporting ATPase VA gene" [UniProtKB:O60312] synonym: "ATP10C" EXACT [UniProtKB:O60312] synonym: "ATPVC" EXACT [UniProtKB:O60312] synonym: "KIAA0566" EXACT [UniProtKB:O60312] xref: EMBL:AB011138 xref: EMBL:AB051358 xref: EMBL:AY029487 xref: EMBL:AY029488 xref: EMBL:AY029489 xref: EMBL:AY029490 xref: EMBL:AY029491 xref: EMBL:AY029492 xref: EMBL:AY029493 xref: EMBL:AY029494 xref: EMBL:AY029495 xref: EMBL:AY029496 xref: EMBL:AY029497 xref: EMBL:AY029498 xref: EMBL:AY029499 xref: EMBL:AY029500 xref: EMBL:AY029501 xref: EMBL:AY029502 xref: EMBL:AY029503 xref: EMBL:AY029504 xref: EMBL:BC052251 xref: HGNC:HGNC:13542 xref: UniGene:Hs.659258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054544 ! AT10A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017090 name: ATP1A3_human def: "Sodium/potassium-transporting ATPase subunit alpha-3 gene" [UniProtKB:P13637] xref: EMBL:BC009282 xref: EMBL:BC009394 xref: EMBL:BC015566 xref: EMBL:M27570 xref: EMBL:M27573 xref: EMBL:M27577 xref: EMBL:M28284 xref: EMBL:M28285 xref: EMBL:M28286 xref: EMBL:M28287 xref: EMBL:M28289 xref: EMBL:M28290 xref: EMBL:M28291 xref: EMBL:M28292 xref: EMBL:M28293 xref: EMBL:M35821 xref: EMBL:M35822 xref: EMBL:M37436 xref: EMBL:M37437 xref: EMBL:M37438 xref: EMBL:M37439 xref: EMBL:M37440 xref: EMBL:M37441 xref: EMBL:M37442 xref: EMBL:M37443 xref: EMBL:M37444 xref: EMBL:M37445 xref: EMBL:M37447 xref: EMBL:M37448 xref: EMBL:M37449 xref: EMBL:M37450 xref: EMBL:M37451 xref: EMBL:M37452 xref: EMBL:M37453 xref: EMBL:M37454 xref: EMBL:M37455 xref: EMBL:M37456 xref: EMBL:M37457 xref: EMBL:M37462 xref: EMBL:X12910 xref: EMBL:X12911 xref: EMBL:X12912 xref: EMBL:X12913 xref: EMBL:X12914 xref: EMBL:X12915 xref: EMBL:X12916 xref: EMBL:X12917 xref: EMBL:X12919 xref: EMBL:X12920 xref: EMBL:X12921 xref: EMBL:X12922 xref: EMBL:X12923 xref: HGNC:HGNC:801 xref: UniGene:Hs.515427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055016 ! AT1A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017091 name: ATP8A2_human def: "Probable phospholipid-transporting ATPase IB gene" [UniProtKB:Q9NTI2] synonym: "ATPIB" EXACT [UniProtKB:Q9NTI2] xref: EMBL:AF236871 xref: EMBL:AK094653 xref: EMBL:AL136438 xref: EMBL:AL137256 xref: EMBL:AL138815 xref: EMBL:AL138958 xref: EMBL:AL157366 xref: EMBL:AL356316 xref: EMBL:AL390129 xref: EMBL:AL669971 xref: EMBL:BX537836 xref: HGNC:HGNC:13533 xref: UniGene:Hs.444957 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058925 ! AT8A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017092 name: ATP8B1_human def: "Probable phospholipid-transporting ATPase IC gene" [UniProtKB:O43520] synonym: "ATPIC" EXACT [UniProtKB:O43520] synonym: "FIC1" EXACT [UniProtKB:O43520] synonym: "PFIC" EXACT [UniProtKB:O43520] xref: EMBL:AF032442 xref: EMBL:AF038007 xref: EMBL:BC003534 xref: HGNC:HGNC:3706 xref: UniGene:Hs.216623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054485 ! AT8B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017093 name: ATF1_human def: "Cyclic AMP-dependent transcription factor ATF-1 gene" [UniProtKB:P18846] xref: EMBL:BC029619 xref: EMBL:X55544 xref: HGNC:HGNC:783 xref: UniGene:Hs.648565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055105 ! ATF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017094 name: ATF6_human def: "Cyclic AMP-dependent transcription factor ATF-6 alpha gene" [UniProtKB:P18850] xref: EMBL:AB015856 xref: EMBL:AF005887 xref: EMBL:AL359541 xref: EMBL:AL391825 xref: EMBL:AL450995 xref: EMBL:BC014969 xref: EMBL:BC071997 xref: HGNC:HGNC:791 xref: UniGene:Hs.492740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018951 ! ATF6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017095 name: CREBL1_human def: "Cyclic AMP-dependent transcription factor ATF-6 beta gene" [UniProtKB:Q99941] synonym: "G13" EXACT [UniProtKB:Q99941] xref: EMBL:AL049547 xref: EMBL:AL662828 xref: EMBL:AL662884 xref: EMBL:CH471081 xref: EMBL:CR753803 xref: EMBL:CR925796 xref: EMBL:U31903 xref: EMBL:U52693 xref: EMBL:U52694 xref: EMBL:U52696 xref: EMBL:U52701 xref: EMBL:U89337 xref: EMBL:X98053 xref: EMBL:X98054 xref: HGNC:HGNC:2349 xref: UniGene:Hs.42853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058463 ! ATF6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017096 name: ATG10_human def: "Autophagy-related protein 10 gene" [UniProtKB:Q9H0Y0] synonym: "APG10L" EXACT [UniProtKB:Q9H0Y0] synonym: "PP12616" EXACT [UniProtKB:Q9H0Y0] xref: EMBL:AF318326 xref: EMBL:AK024016 xref: EMBL:AL136912 xref: EMBL:BC004551 xref: EMBL:BC027718 xref: EMBL:BC029268 xref: HGNC:HGNC:20315 xref: UniGene:Hs.700785 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058658 ! ATG10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017097 name: ATG7_human def: "Autophagy-related protein 7 gene" [UniProtKB:O95352] synonym: "APG7L" EXACT [UniProtKB:O95352] xref: EMBL:AF094516 xref: EMBL:AL122075 xref: EMBL:BC000091 xref: HGNC:HGNC:16935 xref: UniGene:Hs.38032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054750 ! ATG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017098 name: ADAMTSL4_human def: "ADAMTS-like protein 4 precursor gene" [UniProtKB:Q6UY14] synonym: "PP1396" EXACT [UniProtKB:Q6UY14] synonym: "TSRC1" EXACT [UniProtKB:Q6UY14] synonym: "UNQ2803/PRO34012" EXACT [UniProtKB:Q6UY14] xref: EMBL:AF217974 xref: EMBL:AL356356 xref: EMBL:AY358122 xref: EMBL:BC027478 xref: EMBL:BC071852 xref: EMBL:BC094811 xref: HGNC:HGNC:19706 xref: UniGene:Hs.516243 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019657 ! ATL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017099 name: ATOH1_human def: "Protein atonal homolog 1 gene" [UniProtKB:Q92858] synonym: "ATH1" EXACT [UniProtKB:Q92858] xref: EMBL:BC069145 xref: EMBL:BC069594 xref: EMBL:BC069604 xref: EMBL:BC113623 xref: EMBL:BC113625 xref: EMBL:U61148 xref: HGNC:HGNC:797 xref: UniGene:Hs.532680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058108 ! ATOH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017100 name: ATOH7_human def: "Protein atonal homolog 7 gene" [UniProtKB:Q8N100] xref: EMBL:AF418922 xref: EMBL:BC032621 xref: EMBL:BK000277 xref: HGNC:HGNC:13907 xref: UniGene:Hs.175396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057420 ! ATOH7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017101 name: ATOH8_human def: "Protein atonal homolog 8 gene" [UniProtKB:Q96SQ7] synonym: "HATH6" EXACT [UniProtKB:Q96SQ7] xref: EMBL:AF529205 xref: EMBL:AK027614 xref: EMBL:AK074681 xref: EMBL:AL831857 xref: EMBL:BC021207 xref: EMBL:BC094832 xref: HGNC:HGNC:24126 xref: UniGene:Hs.135569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058394 ! ATOH8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017102 name: ATP7A_human def: "Copper-transporting ATPase 1 gene" [UniProtKB:Q04656] synonym: "MC1" EXACT [UniProtKB:Q04656] synonym: "MNK" EXACT [UniProtKB:Q04656] xref: EMBL:AY011418 xref: EMBL:L06133 xref: EMBL:L06476 xref: EMBL:U27361 xref: EMBL:U27362 xref: EMBL:U27363 xref: EMBL:U27365 xref: EMBL:U27366 xref: EMBL:U27367 xref: EMBL:U27368 xref: EMBL:U27369 xref: EMBL:U27370 xref: EMBL:U27371 xref: EMBL:U27372 xref: EMBL:U27373 xref: EMBL:U27374 xref: EMBL:U27375 xref: EMBL:U27376 xref: EMBL:U27377 xref: EMBL:U27378 xref: EMBL:U27379 xref: EMBL:U27380 xref: EMBL:U27381 xref: EMBL:X69208 xref: EMBL:X82336 xref: EMBL:X82337 xref: EMBL:X82338 xref: EMBL:X82339 xref: EMBL:X82340 xref: EMBL:X82341 xref: EMBL:X82342 xref: EMBL:X82343 xref: EMBL:X82344 xref: EMBL:X82345 xref: EMBL:X82346 xref: EMBL:X82347 xref: EMBL:X82348 xref: EMBL:X82349 xref: EMBL:X82350 xref: EMBL:X82351 xref: EMBL:X82352 xref: EMBL:X82353 xref: EMBL:X82354 xref: EMBL:X82355 xref: EMBL:X82356 xref: EMBL:Z94753 xref: EMBL:Z94801 xref: HGNC:HGNC:869 xref: UniGene:Hs.496414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055732 ! ATP7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017103 name: ADAMTS13_human def: "A disintegrin and metalloproteinase with thrombospondin motifs 13 precursor gene" [UniProtKB:Q76LX8] synonym: "C9orf8" EXACT [UniProtKB:Q76LX8] synonym: "UNQ6102/PRO20085" EXACT [UniProtKB:Q76LX8] xref: EMBL:AB069698 xref: EMBL:AF414401 xref: EMBL:AJ305314 xref: EMBL:AJ420810 xref: EMBL:AL136809 xref: EMBL:AL158826 xref: EMBL:AL593848 xref: EMBL:AY055376 xref: EMBL:AY358118 xref: EMBL:DQ422807 xref: HGNC:HGNC:1366 xref: UniGene:Hs.131433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057108 ! ATS13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017104 name: AVEN_human def: "Cell death regulator Aven gene" [UniProtKB:Q9NQS1] xref: EMBL:AF283508 xref: EMBL:BC010488 xref: EMBL:BC063533 xref: HGNC:HGNC:13509 xref: UniGene:Hs.555966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058871 ! AVEN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017105 name: ACVR2B_human def: "Activin receptor type-2B precursor gene" [UniProtKB:Q13705] xref: EMBL:AB008681 xref: EMBL:AF060199 xref: EMBL:AF060200 xref: EMBL:AF060201 xref: EMBL:AF060202 xref: EMBL:BC096243 xref: EMBL:BC096244 xref: EMBL:BC099642 xref: EMBL:X77533 xref: HGNC:HGNC:174 xref: UniGene:Hs.174273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055940 ! AVR2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017106 name: AXIN2_human def: "Axin-2 gene" [UniProtKB:Q9Y2T1] xref: EMBL:AB052751 xref: EMBL:AF078165 xref: EMBL:AF205888 xref: EMBL:BC101533 xref: HGNC:HGNC:904 xref: UniGene:Hs.156527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059315 ! AXN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017107 name: AXUD1_human def: "Axin-1 up-regulated gene 1 protein gene" [UniProtKB:Q96S65] synonym: "CSRNP1" EXACT [UniProtKB:Q96S65] synonym: "TAIP3" EXACT [UniProtKB:Q96S65] xref: EMBL:AB053121 xref: EMBL:AB063301 xref: EMBL:AL117565 xref: EMBL:BC038949 xref: HGNC:HGNC:14300 xref: UniGene:Hs.370950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058387 ! AXUD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017108 name: BCL2L14_human def: "Apoptosis facilitator Bcl-2-like 14 protein gene" [UniProtKB:Q9BZR8] synonym: "BCLG" EXACT [UniProtKB:Q9BZR8] xref: EMBL:AF281254 xref: EMBL:AF281255 xref: EMBL:AY040274 xref: EMBL:BC025778 xref: HGNC:HGNC:16657 xref: UniGene:Hs.210343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058605 ! B2L14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017109 name: BCL2A1_human def: "Bcl-2-related protein A1 gene" [UniProtKB:Q16548] synonym: "BCL2L5" EXACT [UniProtKB:Q16548] synonym: "BFL1" EXACT [UniProtKB:Q16548] synonym: "GRS" EXACT [UniProtKB:Q16548] synonym: "HBPA1" EXACT [UniProtKB:Q16548] xref: EMBL:BC016281 xref: EMBL:BT007103 xref: EMBL:U27467 xref: EMBL:U29680 xref: EMBL:Y09397 xref: HGNC:HGNC:991 xref: UniGene:Hs.227817 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056148 ! B2LA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017110 name: B4GALNT2_human def: "Beta-1,4 N-acetylgalactosaminyltransferase 2 gene" [UniProtKB:Q8NHY0] synonym: "GALGT2" EXACT [UniProtKB:Q8NHY0] xref: EMBL:AF510036 xref: EMBL:AJ517770 xref: EMBL:AJ517771 xref: EMBL:BC113675 xref: EMBL:BC113677 xref: HGNC:HGNC:24136 xref: UniGene:Hs.374679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057878 ! B4GN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017111 name: B4GALT1_human def: "Beta-1,4-galactosyltransferase 1 gene" [UniProtKB:P15291] synonym: "GGTB2" EXACT [UniProtKB:P15291] xref: EMBL:AL161445 xref: EMBL:D29805 xref: EMBL:M13701 xref: EMBL:M22921 xref: EMBL:M70427 xref: EMBL:M70428 xref: EMBL:M70429 xref: EMBL:M70430 xref: EMBL:M70431 xref: EMBL:M70432 xref: EMBL:U10472 xref: EMBL:U10473 xref: EMBL:U10474 xref: EMBL:X13223 xref: EMBL:X14085 xref: EMBL:X55415 xref: HGNC:HGNC:924 xref: UniGene:Hs.651277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055034 ! B4GT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017112 name: B4GALT7_human def: "Beta-1,4-galactosyltransferase 7 gene" [UniProtKB:Q9UBV7] synonym: "UNQ748/PRO1478" EXACT [UniProtKB:Q9UBV7] synonym: "XGALT1" EXACT [UniProtKB:Q9UBV7] xref: EMBL:AB028600 xref: EMBL:AF142675 xref: EMBL:AJ005382 xref: EMBL:AY358578 xref: EMBL:BC007317 xref: EMBL:BC062983 xref: EMBL:BC072403 xref: HGNC:HGNC:930 xref: UniGene:Hs.455109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059087 ! B4GT7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017113 name: BACE2_human def: "Beta-secretase 2 precursor gene" [UniProtKB:Q9Y5Z0] synonym: "AEPLC" EXACT [UniProtKB:Q9Y5Z0] synonym: "ALP56" EXACT [UniProtKB:Q9Y5Z0] synonym: "ASP21" EXACT [UniProtKB:Q9Y5Z0] synonym: "UNQ418/PRO852" EXACT [UniProtKB:Q9Y5Z0] xref: EMBL:AF050171 xref: EMBL:AF117892 xref: EMBL:AF178532 xref: EMBL:AF188276 xref: EMBL:AF188277 xref: EMBL:AF200192 xref: EMBL:AF200342 xref: EMBL:AF204944 xref: EMBL:AL163284 xref: EMBL:AL163285 xref: EMBL:AY358927 xref: EMBL:BC014453 xref: EMBL:CH471079 xref: HGNC:HGNC:934 xref: UniGene:Hs.529408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059002 ! Q9NZL1_HUMAN relationship: codes_for CCO:B0059003 ! Q9NZL2_HUMAN relationship: codes_for CCO:B0059394 ! BACE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017114 name: BACH1_human def: "Transcription regulator protein BACH1 gene" [UniProtKB:O14867] xref: EMBL:AB002803 xref: EMBL:AF026199 xref: EMBL:AF026200 xref: EMBL:AF124731 xref: EMBL:AL163249 xref: EMBL:AP001705 xref: EMBL:BC063307 xref: HGNC:HGNC:935 xref: UniGene:Hs.154276 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054384 ! BACH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017115 name: BACH2_human def: "Transcription regulator protein BACH2 gene" [UniProtKB:Q9BYV9] xref: EMBL:AB208889 xref: EMBL:AF357835 xref: EMBL:AJ271878 xref: EMBL:AL121787 xref: EMBL:AL353692 xref: HGNC:HGNC:14078 xref: UniGene:Hs.269764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058585 ! BACH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017116 name: BAG1_human def: "BAG family molecular chaperone regulator 1 gene" [UniProtKB:Q99933] synonym: "HAP" EXACT [UniProtKB:Q99933] xref: EMBL:AF022224 xref: EMBL:AF116273 xref: EMBL:BC001936 xref: EMBL:BC014774 xref: EMBL:U46917 xref: EMBL:Z35491 xref: HGNC:HGNC:937 xref: UniGene:Hs.377484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058462 ! BAG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017117 name: BAG3_human def: "BAG family molecular chaperone regulator 3 gene" [UniProtKB:O95817] synonym: "BIS" EXACT [UniProtKB:O95817] xref: EMBL:AF071218 xref: EMBL:AF095193 xref: EMBL:AF127139 xref: EMBL:AL137582 xref: EMBL:BC006418 xref: EMBL:BC014656 xref: EMBL:BC107786 xref: HGNC:HGNC:939 xref: UniGene:Hs.702046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054796 ! BAG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017118 name: BAG4_human def: "BAG family molecular chaperone regulator 4 gene" [UniProtKB:O95429] synonym: "SODD" EXACT [UniProtKB:O95429] xref: EMBL:AF095194 xref: EMBL:AF111116 xref: EMBL:BC038505 xref: HGNC:HGNC:940 xref: UniGene:Hs.194726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054763 ! BAG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017119 name: BAI1_human def: "Brain-specific angiogenesis inhibitor 1 precursor gene" [UniProtKB:O14514] xref: EMBL:AB005297 xref: HGNC:HGNC:943 xref: UniGene:Hs.194654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054348 ! BAI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017120 name: BAI2_human def: "Brain-specific angiogenesis inhibitor 2 precursor gene" [UniProtKB:O60241] xref: EMBL:AB005298 xref: EMBL:AB065648 xref: EMBL:AC114488 xref: EMBL:AL354919 xref: HGNC:HGNC:944 xref: UniGene:Hs.524138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021202 ! A2A3C6_HUMAN relationship: codes_for CCO:B0021203 ! A2A3C1_HUMAN relationship: codes_for CCO:B0021206 ! A2A3C4_HUMAN relationship: codes_for CCO:B0021208 ! A2A3C2_HUMAN relationship: codes_for CCO:B0021209 ! A2A3C3_HUMAN relationship: codes_for CCO:B0021210 ! BAI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017121 name: BAI3_human def: "Brain-specific angiogenesis inhibitor 3 precursor gene" [UniProtKB:O60242] synonym: "KIAA0550" EXACT [UniProtKB:O60242] xref: EMBL:AB005299 xref: EMBL:AB011122 xref: EMBL:AL133378 xref: EMBL:AL158051 xref: EMBL:AL160401 xref: EMBL:AL356117 xref: EMBL:AL359714 xref: EMBL:AL391807 xref: EMBL:BC111720 xref: EMBL:CH471051 xref: HGNC:HGNC:945 xref: UniGene:Hs.13261 xref: UniGene:Hs.703080 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054536 ! BAI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017122 name: BAIAP2_human def: "Brain-specific angiogenesis inhibitor 1-associated protein 2 gene" [UniProtKB:Q9UQB8] xref: EMBL:AB015019 xref: EMBL:AB015020 xref: EMBL:AB017119 xref: EMBL:AB017120 xref: EMBL:AB104726 xref: EMBL:AK222670 xref: EMBL:BC014020 xref: EMBL:BC032559 xref: EMBL:U70669 xref: HGNC:HGNC:947 xref: UniGene:Hs.128316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059278 ! BAIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017123 name: BCL2L7P1_human def: "Putative Bcl-2 homologous antagonist/killer 2 gene" [UniProtKB:Q13014] synonym: "BAK2" EXACT [UniProtKB:Q13014] xref: EMBL:BX640505 xref: EMBL:U16812 xref: HGNC:HGNC:996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055866 ! BAK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017124 name: BAP1_human def: "Ubiquitin carboxyl-terminal hydrolase BAP1 gene" [UniProtKB:Q92560] synonym: "hucep-6" EXACT [UniProtKB:Q92560] synonym: "KIAA0272" EXACT [UniProtKB:Q92560] xref: EMBL:AF045581 xref: EMBL:AY130008 xref: EMBL:BC001596 xref: EMBL:D87462 xref: EMBL:D88812 xref: HGNC:HGNC:950 xref: UniGene:Hs.106674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058063 ! BAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017125 name: BARHL1_human def: "BarH-like 1 homeobox protein gene" [UniProtKB:Q9BZE3] synonym: "FKSG31" EXACT [UniProtKB:Q9BZE3] xref: EMBL:AF321618 xref: EMBL:AF325688 xref: EMBL:AJ237816 xref: EMBL:AK054797 xref: HGNC:HGNC:953 xref: UniGene:Hs.283809 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058597 ! BARH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017126 name: BARHL2_human def: "BarH-like 2 homeobox protein gene" [UniProtKB:Q9NY43] xref: EMBL:AJ251753 xref: EMBL:AY338397 xref: EMBL:BC126439 xref: EMBL:BC126441 xref: HGNC:HGNC:954 xref: UniGene:Hs.451956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058958 ! BARH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017127 name: BARX1_human def: "Homeobox protein BarH-like 1 gene" [UniProtKB:Q9HBU1] xref: EMBL:AF213356 xref: EMBL:AL357073 xref: EMBL:BC009458 xref: EMBL:BC064363 xref: EMBL:CH471089 xref: HGNC:HGNC:955 xref: UniGene:Hs.164960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058792 ! BARX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017128 name: BSG_human def: "Basigin precursor gene" [UniProtKB:P35613] synonym: "UNQ6505/PRO21383" EXACT [UniProtKB:P35613] xref: EMBL:AB072923 xref: EMBL:AB085790 xref: EMBL:AC005559 xref: EMBL:AF042848 xref: EMBL:AF042849 xref: EMBL:AF042850 xref: EMBL:AF042851 xref: EMBL:AF042852 xref: EMBL:AF042853 xref: EMBL:AF042854 xref: EMBL:AF548371 xref: EMBL:AY358113 xref: EMBL:AY942196 xref: EMBL:BC009040 xref: EMBL:D45131 xref: EMBL:L10240 xref: EMBL:L20471 xref: EMBL:M87879 xref: EMBL:X64364 xref: HGNC:HGNC:1116 xref: UniGene:Hs.591382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055296 ! BASI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017129 name: BATF2_human def: "Basic leucine zipper transcriptional factor ATF-like 2 gene" [UniProtKB:Q8N1L9] xref: EMBL:AK096702 xref: EMBL:BC012330 xref: HGNC:HGNC:25163 xref: UniGene:Hs.124840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057430 ! BATF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017130 name: BATF3_human def: "Basic leucine zipper transcriptional factor ATF-like 3 gene" [UniProtKB:Q9NR55] synonym: "SNFT" EXACT [UniProtKB:Q9NR55] xref: EMBL:AF255346 xref: EMBL:AL591647 xref: EMBL:BC117489 xref: EMBL:BC117491 xref: EMBL:CH471100 xref: HGNC:HGNC:28915 xref: UniGene:Hs.62919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058887 ! BATF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017131 name: BAZ1A_human def: "Bromodomain adjacent to zinc finger domain protein 1A gene" [UniProtKB:Q9NRL2] synonym: "ACF1" EXACT [UniProtKB:Q9NRL2] synonym: "HSPC317" EXACT [UniProtKB:Q9NRL2] synonym: "WCRF180" EXACT [UniProtKB:Q9NRL2] xref: EMBL:AB032252 xref: EMBL:AF161435 xref: EMBL:AF213467 xref: EMBL:AF221130 xref: EMBL:AL050089 xref: HGNC:HGNC:960 xref: UniGene:Hs.509140 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058901 ! BAZ1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017132 name: BAZ1B_human def: "Bromodomain adjacent to zinc finger domain protein 1B gene" [UniProtKB:Q9UIG0] synonym: "WBSC10" EXACT [UniProtKB:Q9UIG0] synonym: "WBSCR10" EXACT [UniProtKB:Q9UIG0] synonym: "WBSCR9" EXACT [UniProtKB:Q9UIG0] synonym: "WSTF" EXACT [UniProtKB:Q9UIG0] xref: EMBL:AB032253 xref: EMBL:AC005074 xref: EMBL:AC005089 xref: EMBL:AF072810 xref: EMBL:AF084479 xref: HGNC:HGNC:961 xref: UniGene:Hs.694847 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059161 ! BAZ1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017133 name: BAZ2A_human def: "Bromodomain adjacent to zinc finger domain protein 2A gene" [UniProtKB:Q9UIF9] synonym: "KIAA0314" EXACT [UniProtKB:Q9UIF9] synonym: "TIP5" EXACT [UniProtKB:Q9UIF9] xref: EMBL:AB002312 xref: EMBL:AB032254 xref: EMBL:AF000422 xref: EMBL:BC008965 xref: HGNC:HGNC:962 xref: UniGene:Hs.314263 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059160 ! BAZ2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017134 name: BAZ2B_human def: "Bromodomain adjacent to zinc finger domain protein 2B gene" [UniProtKB:Q9UIF8] synonym: "KIAA1476" EXACT [UniProtKB:Q9UIF8] xref: EMBL:AB032255 xref: EMBL:AB040909 xref: EMBL:AK027612 xref: EMBL:AL080173 xref: EMBL:AL834381 xref: EMBL:BC012576 xref: HGNC:HGNC:963 xref: UniGene:Hs.470369 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059159 ! BAZ2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017135 name: BBX_human def: "HMG box transcription factor BBX gene" [UniProtKB:Q8WY36] synonym: "HBP2" EXACT [UniProtKB:Q8WY36] xref: EMBL:AF276948 xref: EMBL:AF276949 xref: EMBL:AF454941 xref: EMBL:AF454942 xref: EMBL:AL136769 xref: EMBL:AL834307 xref: EMBL:BC012837 xref: EMBL:BC110903 xref: EMBL:BC131718 xref: HGNC:HGNC:14422 xref: UniGene:Hs.124366 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053737 ! A2RRM7_HUMAN relationship: codes_for CCO:B0058038 ! BBX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017136 name: BCL11B_human def: "B-cell lymphoma/leukemia 11B gene" [UniProtKB:Q9C0K0] synonym: "CTIP2" EXACT [UniProtKB:Q9C0K0] synonym: "RIT1" EXACT [UniProtKB:Q9C0K0] xref: EMBL:AB043584 xref: EMBL:AJ404614 xref: HGNC:HGNC:13222 xref: UniGene:Hs.699440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058622 ! BC11B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017137 name: BCKDK_human def: "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor gene" [UniProtKB:O14874] xref: EMBL:AF026548 xref: EMBL:BC007363 xref: HGNC:HGNC:16902 xref: UniGene:Hs.513520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054385 ! BCKD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017138 name: BCL7A_human def: "B-cell CLL/lymphoma 7 protein family member A gene" [UniProtKB:Q4VC05] xref: EMBL:BC094723 xref: EMBL:X89984 xref: HGNC:HGNC:1004 xref: UniGene:Hs.530970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056331 ! BCL7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017139 name: BCL9L_human def: "B-cell CLL/lymphoma 9-like protein gene" [UniProtKB:Q86UU0] synonym: "DLNB11" EXACT [UniProtKB:Q86UU0] xref: EMBL:AB094091 xref: EMBL:AK122650 xref: EMBL:AK122882 xref: EMBL:AY296059 xref: EMBL:BC033257 xref: EMBL:CH471065 xref: HGNC:HGNC:23688 xref: UniGene:Hs.414740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057256 ! BCL9L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017140 name: BCLAF1_human def: "Bcl-2-associated transcription factor 1 gene" [UniProtKB:Q9NYF8] synonym: "BTF" EXACT [UniProtKB:Q9NYF8] synonym: "KIAA0164" EXACT [UniProtKB:Q9NYF8] xref: EMBL:AF249273 xref: EMBL:AL121713 xref: EMBL:BC047687 xref: EMBL:BC047887 xref: EMBL:BC056894 xref: EMBL:BC063846 xref: EMBL:D79986 xref: HGNC:HGNC:16863 xref: UniGene:Hs.486542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058962 ! BCLF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017141 name: BCL2L2_human def: "Apoptosis regulator Bcl-W gene" [UniProtKB:Q92843] synonym: "BCLW" EXACT [UniProtKB:Q92843] synonym: "KIAA0271" EXACT [UniProtKB:Q92843] xref: EMBL:BC021198 xref: EMBL:BC104789 xref: EMBL:BC113522 xref: EMBL:BT019549 xref: EMBL:D87461 xref: EMBL:U59747 xref: HGNC:HGNC:995 xref: UniGene:Hs.410026 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028585 ! BCLW_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017142 name: BCOR_human def: "BCL-6 corepressor gene" [UniProtKB:Q6W2J9] synonym: "KIAA1575" EXACT [UniProtKB:Q6W2J9] xref: EMBL:AB046795 xref: EMBL:AF317391 xref: EMBL:AF317392 xref: EMBL:AK000292 xref: EMBL:AK074286 xref: EMBL:AY316592 xref: EMBL:BC009675 xref: EMBL:BC063536 xref: HGNC:HGNC:20893 xref: UniGene:Hs.659681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056966 ! BCOR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017143 name: BDP1_human def: "Transcription factor TFIIIB component B'' homolog gene" [UniProtKB:A6H8Y1] synonym: "KIAA1241" EXACT [UniProtKB:A6H8Y1] synonym: "KIAA1689" EXACT [UniProtKB:A6H8Y1] synonym: "TFNR" EXACT [UniProtKB:A6H8Y1] xref: EMBL:AB033067 xref: EMBL:AB051476 xref: EMBL:AF176695 xref: EMBL:AF298151 xref: EMBL:AF298152 xref: EMBL:AJ238520 xref: EMBL:AJ278892 xref: EMBL:AJ279120 xref: EMBL:AJ279121 xref: EMBL:AJ279122 xref: EMBL:AJ279123 xref: EMBL:AJ279124 xref: EMBL:AJ279125 xref: EMBL:AJ279126 xref: EMBL:AJ279127 xref: EMBL:AJ279128 xref: EMBL:AJ279129 xref: EMBL:AJ279130 xref: EMBL:AJ279131 xref: EMBL:AJ279132 xref: EMBL:AJ279133 xref: EMBL:AJ279134 xref: EMBL:AJ279135 xref: EMBL:AJ279136 xref: EMBL:AJ279137 xref: EMBL:AJ279138 xref: EMBL:AJ279139 xref: EMBL:AJ279140 xref: EMBL:AJ279141 xref: EMBL:AJ279142 xref: EMBL:AJ279143 xref: EMBL:AJ279144 xref: EMBL:AJ279145 xref: EMBL:AJ279146 xref: EMBL:AJ279147 xref: EMBL:AJ279148 xref: EMBL:AJ279149 xref: EMBL:AJ279150 xref: EMBL:AK057871 xref: EMBL:BC032146 xref: EMBL:BC146792 xref: EMBL:BX641011 xref: EMBL:CR749229 xref: EMBL:CR749289 xref: HGNC:HGNC:13652 xref: UniGene:Hs.258272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053780 ! BDP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017144 name: BFAR_human def: "Bifunctional apoptosis regulator gene" [UniProtKB:Q9NZS9] synonym: "BAR" EXACT [UniProtKB:Q9NZS9] synonym: "RNF47" EXACT [UniProtKB:Q9NZS9] xref: EMBL:AF173003 xref: EMBL:BC003054 xref: HGNC:HGNC:17613 xref: UniGene:Hs.435556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059015 ! BFAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017145 name: BHLHF42_human def: "Class B basic helix-loop-helix factor 42 gene" [UniProtKB:Q7RTU4] xref: EMBL:AC032044 xref: EMBL:BK000140 xref: UniGene:Hs.647427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057135 ! BHL42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017146 name: BHLHB3_human def: "Class B basic helix-loop-helix protein 3 gene" [UniProtKB:Q9C0J9] synonym: "DEC2" EXACT [UniProtKB:Q9C0J9] synonym: "SHARP1" EXACT [UniProtKB:Q9C0J9] xref: EMBL:AB044088 xref: HGNC:HGNC:16617 xref: UniGene:Hs.177841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058621 ! BHLH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017147 name: BHLHB4_human def: "Class B basic helix-loop-helix protein 4 gene" [UniProtKB:Q8NDY6] xref: EMBL:AL121673 xref: EMBL:BK000274 xref: HGNC:HGNC:16093 xref: UniGene:Hs.551230 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057586 ! BHLH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017148 name: BHLHB5_human def: "Class B basic helix-loop-helix protein 5 gene" [UniProtKB:Q8NFJ8] synonym: "TNRC20" EXACT [UniProtKB:Q8NFJ8] xref: EMBL:AF504925 xref: EMBL:BK000273 xref: HGNC:HGNC:11963 xref: UniGene:Hs.388788 xref: UniGene:Hs.591870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057605 ! BHLH5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017149 name: BHLHB8_human def: "Class B basic helix-loop-helix protein 8 gene" [UniProtKB:Q7RTS1] synonym: "MIST1" EXACT [UniProtKB:Q7RTS1] xref: EMBL:AC025605 xref: EMBL:BC113394 xref: EMBL:BC113396 xref: EMBL:BK000276 xref: HGNC:HGNC:22265 xref: UniGene:Hs.674510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057126 ! BHLH8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017150 name: BHMT_human def: "Betaine--homocysteine S-methyltransferase 1 gene" [UniProtKB:Q93088] xref: EMBL:AF118371 xref: EMBL:AF118372 xref: EMBL:AF118373 xref: EMBL:AF118374 xref: EMBL:AF118375 xref: EMBL:AF118376 xref: EMBL:AF118377 xref: EMBL:AF118378 xref: EMBL:BC012616 xref: EMBL:U50929 xref: HGNC:HGNC:1047 xref: UniGene:Hs.80756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058123 ! BHMT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017151 name: TEGT_human def: "Bax inhibitor 1 gene" [UniProtKB:P55061] synonym: "BI1" EXACT [UniProtKB:P55061] synonym: "TMBIM6" EXACT [UniProtKB:P55061] xref: EMBL:AF033095 xref: EMBL:AY736129 xref: EMBL:BC000916 xref: EMBL:BC036203 xref: EMBL:X75861 xref: HGNC:HGNC:11723 xref: UniGene:Hs.35052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055526 ! BI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017152 name: BAIAP2L1_human def: "Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 gene" [UniProtKB:Q9UHR4] synonym: "IRTKS" EXACT [UniProtKB:Q9UHR4] xref: EMBL:AC004841 xref: EMBL:AC093169 xref: EMBL:AC093799 xref: EMBL:AF119666 xref: EMBL:AK027142 xref: EMBL:BC013888 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: HGNC:HGNC:21649 xref: UniGene:Hs.656063 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059147 ! BI2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017153 name: BAIAP2L2_human def: "Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 gene" [UniProtKB:Q6UXY1] synonym: "UNQ9336/PRO34007" EXACT [UniProtKB:Q6UXY1] xref: EMBL:AK026235 xref: EMBL:AL022322 xref: EMBL:AL031587 xref: EMBL:AY358164 xref: EMBL:BC015619 xref: EMBL:CH471095 xref: HGNC:HGNC:26203 xref: UniGene:Hs.474822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056956 ! BI2L2_HUMAN relationship: codes_for CCO:B0058733 ! Q9H661_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017154 name: ARFGEF1_human def: "Brefeldin A-inhibited guanine nucleotide-exchange protein 1 gene" [UniProtKB:Q9Y6D6] synonym: "ARFGEP1" EXACT [UniProtKB:Q9Y6D6] synonym: "BIG1" EXACT [UniProtKB:Q9Y6D6] xref: EMBL:AF084520 xref: EMBL:AF111162 xref: EMBL:AK001788 xref: EMBL:AL117446 xref: HGNC:HGNC:15772 xref: UniGene:Hs.656902 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024694 ! BIG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017155 name: ARFGEF2_human def: "Brefeldin A-inhibited guanine nucleotide-exchange protein 2 gene" [UniProtKB:Q9Y6D5] synonym: "ARFGEP2" EXACT [UniProtKB:Q9Y6D5] synonym: "BIG2" EXACT [UniProtKB:Q9Y6D5] xref: EMBL:AF084521 xref: EMBL:AL049537 xref: EMBL:AL121903 xref: HGNC:HGNC:15853 xref: UniGene:Hs.62578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024696 ! BIG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017156 name: ARFGEF3_human def: "Brefeldin A-inhibited guanine nucleotide-exchange protein 3 gene" [UniProtKB:Q5TH69] synonym: "BIG3" EXACT [UniProtKB:Q5TH69] synonym: "KIAA1244" EXACT [UniProtKB:Q5TH69] xref: EMBL:AB033070 xref: EMBL:AF413080 xref: EMBL:AL031003 xref: EMBL:AL031433 xref: EMBL:AL391240 xref: EMBL:BC014227 xref: EMBL:BC033191 xref: HGNC:HGNC:21213 xref: UniGene:Hs.656215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056626 ! BIG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017157 name: C9orf89_human def: "Bcl10-interacting CARD protein gene" [UniProtKB:Q96LW7] xref: EMBL:AK057716 xref: EMBL:AL451065 xref: EMBL:BC004500 xref: EMBL:BC038856 xref: EMBL:BC091476 xref: HGNC:HGNC:28148 xref: UniGene:Hs.434213 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058276 ! BINCA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017158 name: NAIP_human def: "Baculoviral IAP repeat-containing protein 1 gene" [UniProtKB:Q13075] synonym: "BIRC1" EXACT [UniProtKB:Q13075] xref: EMBL:AB209123 xref: EMBL:AC005031 xref: EMBL:AC044797 xref: EMBL:U19251 xref: EMBL:U21913 xref: EMBL:U80017 xref: HGNC:HGNC:7634 xref: UniGene:Hs.646951 xref: UniGene:Hs.654500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055870 ! BIRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017159 name: BIRC3_human def: "Baculoviral IAP repeat-containing protein 3 gene" [UniProtKB:Q13489] synonym: "API2" EXACT [UniProtKB:Q13489] synonym: "IAP1" EXACT [UniProtKB:Q13489] synonym: "MIHC" EXACT [UniProtKB:Q13489] synonym: "RNF49" EXACT [UniProtKB:Q13489] xref: EMBL:AF070674 xref: EMBL:AF178945 xref: EMBL:AY764389 xref: EMBL:BC037420 xref: EMBL:L49432 xref: EMBL:U37546 xref: EMBL:U45878 xref: HGNC:HGNC:591 xref: UniGene:Hs.127799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055917 ! BIRC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017160 name: BIRC4_human def: "Baculoviral IAP repeat-containing protein 4 gene" [UniProtKB:P98170] synonym: "API3" EXACT [UniProtKB:P98170] synonym: "IAP3" EXACT [UniProtKB:P98170] synonym: "XIAP" EXACT [UniProtKB:P98170] xref: EMBL:AL121601 xref: EMBL:AY886519 xref: EMBL:BC032729 xref: EMBL:U32974 xref: EMBL:U45880 xref: HGNC:HGNC:592 xref: UniGene:Hs.356076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055674 ! BIRC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017161 name: BIRC7_human def: "Baculoviral IAP repeat-containing protein 7 gene" [UniProtKB:Q96CA5] synonym: "KIAP" EXACT [UniProtKB:Q96CA5] synonym: "LIVIN" EXACT [UniProtKB:Q96CA5] synonym: "MLIAP" EXACT [UniProtKB:Q96CA5] synonym: "RNF50" EXACT [UniProtKB:Q96CA5] synonym: "UNQ5800/PRO19607/PRO21344" EXACT [UniProtKB:Q96CA5] xref: EMBL:AF301009 xref: EMBL:AF311388 xref: EMBL:AJ309298 xref: EMBL:AL121827 xref: EMBL:AY358835 xref: EMBL:AY358836 xref: EMBL:BC014475 xref: HGNC:HGNC:13702 xref: UniGene:Hs.256126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058181 ! BIRC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017162 name: BDKRB1_human def: "B1 bradykinin receptor gene" [UniProtKB:P46663] synonym: "BRADYB1" EXACT [UniProtKB:P46663] xref: EMBL:AB065896 xref: EMBL:AJ238044 xref: EMBL:AY275464 xref: EMBL:BC034705 xref: EMBL:U12512 xref: EMBL:U22346 xref: EMBL:U48231 xref: HGNC:HGNC:1029 xref: UniGene:Hs.525572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055378 ! BKRB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017163 name: BDKRB2_human def: "B2 bradykinin receptor gene" [UniProtKB:P30411] synonym: "BKR2" EXACT [UniProtKB:P30411] xref: EMBL:AF378542 xref: EMBL:AY275465 xref: EMBL:BC074894 xref: EMBL:BC074895 xref: EMBL:L27594 xref: EMBL:M88714 xref: EMBL:S45489 xref: EMBL:S56772 xref: EMBL:X69680 xref: EMBL:X86164 xref: EMBL:X86165 xref: HGNC:HGNC:1030 xref: UniGene:Hs.654542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055218 ! BKRB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017164 name: BLNK_human def: "B-cell linker protein gene" [UniProtKB:Q8WV28] synonym: "BASH" EXACT [UniProtKB:Q8WV28] synonym: "SLP65" EXACT [UniProtKB:Q8WV28] xref: EMBL:AF068180 xref: EMBL:AF068181 xref: EMBL:AF180740 xref: EMBL:AF180741 xref: EMBL:AF180742 xref: EMBL:AF180743 xref: EMBL:AF180744 xref: EMBL:AF180745 xref: EMBL:AF180746 xref: EMBL:AF180747 xref: EMBL:AF180748 xref: EMBL:AF180749 xref: EMBL:AF180750 xref: EMBL:AF180751 xref: EMBL:AF180752 xref: EMBL:AF180753 xref: EMBL:AF180754 xref: EMBL:AF180755 xref: EMBL:AF180756 xref: EMBL:BC018906 xref: HGNC:HGNC:14211 xref: UniGene:Hs.665244 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057988 ! BLNK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017165 name: ARNTL_human def: "Aryl hydrocarbon receptor nuclear translocator-like protein 1 gene" [UniProtKB:O00327] synonym: "BMAL1" EXACT [UniProtKB:O00327] synonym: "MOP3" EXACT [UniProtKB:O00327] xref: EMBL:AB000812 xref: EMBL:AB000813 xref: EMBL:AB000814 xref: EMBL:AB000815 xref: EMBL:AB000816 xref: EMBL:AF044288 xref: EMBL:AK095749 xref: EMBL:BC041129 xref: EMBL:CH471064 xref: EMBL:D89722 xref: EMBL:EF015894 xref: EMBL:U51627 xref: EMBL:U60415 xref: HGNC:HGNC:701 xref: UniGene:Hs.65734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053730 ! A2I2N6_HUMAN relationship: codes_for CCO:B0054311 ! BMAL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017166 name: ARNTL2_human def: "Aryl hydrocarbon receptor nuclear translocator-like protein 2 gene" [UniProtKB:Q8WYA1] synonym: "BMAL2" EXACT [UniProtKB:Q8WYA1] synonym: "CLIF" EXACT [UniProtKB:Q8WYA1] synonym: "MOP9" EXACT [UniProtKB:Q8WYA1] xref: EMBL:AB039921 xref: EMBL:AF231338 xref: EMBL:AF231339 xref: EMBL:AF246960 xref: EMBL:AF246961 xref: EMBL:AF246962 xref: EMBL:AF246963 xref: EMBL:AF256215 xref: EMBL:BC000172 xref: EMBL:BC125061 xref: EMBL:BC125062 xref: HGNC:HGNC:18984 xref: UniGene:Hs.434269 xref: UniGene:Hs.663740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058041 ! BMAL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017167 name: GDF10_human def: "Bone morphogenetic protein 3b precursor gene" [UniProtKB:P55107] synonym: "BMP3B" EXACT [UniProtKB:P55107] xref: EMBL:D49492 xref: EMBL:D49493 xref: EMBL:L42113 xref: HGNC:HGNC:4215 xref: UniGene:Hs.2171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055528 ! BMP3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017168 name: BMPER_human def: "BMP-binding endothelial regulator protein precursor gene" [UniProtKB:Q8N8U9] synonym: "KIAA1965" EXACT [UniProtKB:Q8N8U9] xref: EMBL:AB075845 xref: EMBL:AK096150 xref: EMBL:AY324650 xref: EMBL:BC060868 xref: HGNC:HGNC:24154 xref: UniGene:Hs.660998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057526 ! BMPER_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017169 name: BNC1_human def: "Zinc finger protein basonuclin-1 gene" [UniProtKB:Q01954] synonym: "BNC" EXACT [UniProtKB:Q01954] xref: EMBL:L03427 xref: EMBL:U59692 xref: EMBL:U59693 xref: EMBL:U59694 xref: HGNC:HGNC:1081 xref: UniGene:Hs.459153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024472 ! BNC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017170 name: BNC2_human def: "Zinc finger protein basonuclin-2 gene" [UniProtKB:Q6ZN30] xref: EMBL:AK000050 xref: EMBL:AK025882 xref: EMBL:AK092247 xref: EMBL:AK131398 xref: EMBL:AL449983 xref: EMBL:AL450003 xref: EMBL:AL450105 xref: EMBL:AY438376 xref: HGNC:HGNC:30988 xref: UniGene:Hs.656581 xref: UniGene:Hs.693437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024477 ! BNC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017171 name: CDC42EP2_human def: "Cdc42 effector protein 2 gene" [UniProtKB:O14613] synonym: "BORG1" EXACT [UniProtKB:O14613] synonym: "CEP2" EXACT [UniProtKB:O14613] xref: EMBL:AF001436 xref: EMBL:AF098290 xref: EMBL:AF163840 xref: EMBL:AF548903 xref: EMBL:BC022337 xref: EMBL:BC075834 xref: EMBL:BT020004 xref: HGNC:HGNC:16263 xref: UniGene:Hs.343380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054357 ! BORG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017172 name: CDC42EP3_human def: "Cdc42 effector protein 3 gene" [UniProtKB:Q9UKI2] synonym: "BORG2" EXACT [UniProtKB:Q9UKI2] synonym: "CEP3" EXACT [UniProtKB:Q9UKI2] xref: EMBL:AC006369 xref: EMBL:AF094521 xref: EMBL:AF104857 xref: EMBL:AF164118 xref: EMBL:AL136842 xref: EMBL:BC019270 xref: EMBL:BT007190 xref: HGNC:HGNC:16943 xref: UniGene:Hs.369574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059193 ! BORG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017173 name: CDC42EP5_human def: "Cdc42 effector protein 5 gene" [UniProtKB:Q6NZY7] synonym: "BORG3" EXACT [UniProtKB:Q6NZY7] synonym: "CEP5" EXACT [UniProtKB:Q6NZY7] xref: EMBL:BC024327 xref: EMBL:BC065910 xref: HGNC:HGNC:17408 xref: UniGene:Hs.415791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056874 ! BORG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017174 name: CDC42EP4_human def: "Cdc42 effector protein 4 gene" [UniProtKB:Q9H3Q1] synonym: "BORG4" EXACT [UniProtKB:Q9H3Q1] synonym: "CEP4" EXACT [UniProtKB:Q9H3Q1] xref: EMBL:AB042237 xref: EMBL:AF099664 xref: EMBL:BC002774 xref: EMBL:BC010451 xref: HGNC:HGNC:17147 xref: UniGene:Hs.176479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058708 ! BORG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017175 name: CDC42EP1_human def: "Cdc42 effector protein 1 gene" [UniProtKB:Q00587] synonym: "BORG5" EXACT [UniProtKB:Q00587] synonym: "CEP1" EXACT [UniProtKB:Q00587] synonym: "MSE55" EXACT [UniProtKB:Q00587] xref: EMBL:AL022315 xref: EMBL:BC009356 xref: EMBL:CR456524 xref: EMBL:M88338 xref: HGNC:HGNC:17014 xref: UniGene:Hs.225356 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055680 ! BORG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017176 name: BPTF_human def: "Nucleosome-remodeling factor subunit BPTF gene" [UniProtKB:Q12830] synonym: "FAC1" EXACT [UniProtKB:Q12830] synonym: "FALZ" EXACT [UniProtKB:Q12830] xref: EMBL:AB032251 xref: EMBL:AC006534 xref: EMBL:AC107377 xref: EMBL:AC134407 xref: EMBL:AY282495 xref: EMBL:BC067234 xref: EMBL:U05237 xref: HGNC:HGNC:3581 xref: UniGene:Hs.444200 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055846 ! BPTF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017177 name: T_human def: "Brachyury protein gene" [UniProtKB:O15178] xref: EMBL:AJ001699 xref: EMBL:AL627443 xref: EMBL:BC098425 xref: HGNC:HGNC:11515 xref: UniGene:Hs.389457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054413 ! BRAC_HUMAN relationship: codes_for CCO:B0056318 ! Q4KMP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017178 name: BRD8_human def: "Bromodomain-containing protein 8 gene" [UniProtKB:Q9H0E9] synonym: "SMAP" EXACT [UniProtKB:Q9H0E9] synonym: "SMAP2" EXACT [UniProtKB:Q9H0E9] xref: EMBL:AB209079 xref: EMBL:AF016270 xref: EMBL:AL136823 xref: EMBL:BC008039 xref: EMBL:BC008076 xref: EMBL:X87613 xref: EMBL:X94234 xref: HGNC:HGNC:19874 xref: UniGene:Hs.519337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058651 ! BRD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017179 name: BRDT_human def: "Bromodomain testis-specific protein gene" [UniProtKB:Q58F21] xref: EMBL:AC114486 xref: EMBL:AF019085 xref: EMBL:AY338951 xref: EMBL:BC017582 xref: EMBL:BC047900 xref: EMBL:BC062700 xref: HGNC:HGNC:1105 xref: UniGene:Hs.482520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056377 ! BRDT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017180 name: BRF2_human def: "Transcription factor IIIB 50 kDa subunit gene" [UniProtKB:Q9HAW0] synonym: "BRFU" EXACT [UniProtKB:Q9HAW0] synonym: "PRO1470" EXACT [UniProtKB:Q9HAW0] xref: EMBL:AF130058 xref: EMBL:AF206673 xref: EMBL:AF298153 xref: EMBL:AK001914 xref: EMBL:BC010648 xref: EMBL:CH471080 xref: HGNC:HGNC:17298 xref: UniGene:Hs.705411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058771 ! BRF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017181 name: BRS3_human def: "Bombesin receptor subtype-3 gene" [UniProtKB:P32247] xref: EMBL:AY585193 xref: EMBL:L08893 xref: EMBL:X76498 xref: EMBL:Z97632 xref: HGNC:HGNC:1113 xref: UniGene:Hs.121484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055257 ! BRS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017182 name: BRWD1_human def: "Bromodomain and WD repeat-containing protein 1 gene" [UniProtKB:Q9NSI6] synonym: "C21orf107" EXACT [UniProtKB:Q9NSI6] synonym: "WDR9" EXACT [UniProtKB:Q9NSI6] xref: EMBL:AB080586 xref: EMBL:AB080587 xref: EMBL:AJ222636 xref: EMBL:AJ238214 xref: EMBL:AJ292465 xref: EMBL:AJ292466 xref: EMBL:AK002177 xref: EMBL:AL163279 xref: HGNC:HGNC:12760 xref: UniGene:Hs.654740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058920 ! BRWD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017183 name: BST2_human def: "Bone marrow stromal antigen 2 precursor gene" [UniProtKB:Q10589] xref: EMBL:AK223124 xref: EMBL:BC033873 xref: EMBL:D28137 xref: HGNC:HGNC:1119 xref: UniGene:Hs.118110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055836 ! BST2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017184 name: BTF3L2_human def: "Transcription factor BTF3 homolog 2 gene" [UniProtKB:Q13891] xref: EMBL:M90355 xref: HGNC:HGNC:1127 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055951 ! BT3L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017185 name: BTF3L3_human def: "Transcription factor BTF3 homolog 3 gene" [UniProtKB:Q13892] xref: EMBL:M90356 xref: HGNC:HGNC:1128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032323 ! BT3L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017186 name: BTBD14B_human def: "BTB/POZ domain-containing protein 14B gene" [UniProtKB:Q96RE7] synonym: "NAC1" EXACT [UniProtKB:Q96RE7] xref: EMBL:AF395817 xref: EMBL:BC055396 xref: HGNC:HGNC:20967 xref: UniGene:Hs.531614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058374 ! BTB14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017187 name: BTF3_human def: "Transcription factor BTF3 gene" [UniProtKB:P20290] synonym: "NACB" EXACT [UniProtKB:P20290] synonym: "OK/SW-cl.8" EXACT [UniProtKB:P20290] xref: EMBL:AB062126 xref: EMBL:BC008062 xref: EMBL:BT007120 xref: EMBL:M90352 xref: EMBL:M90357 xref: EMBL:X53280 xref: EMBL:X53281 xref: EMBL:X74070 xref: HGNC:HGNC:1125 xref: UniGene:Hs.591768 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032333 ! BTF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017188 name: BTG1_human def: "Protein BTG1 gene" [UniProtKB:P62324] xref: EMBL:AY850133 xref: EMBL:BC016759 xref: EMBL:BC064953 xref: EMBL:BT019840 xref: EMBL:X61123 xref: HGNC:HGNC:1130 xref: UniGene:Hs.255935 xref: UniGene:Hs.651357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055615 ! BTG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017189 name: BTG2_human def: "Protein BTG2 gene" [UniProtKB:P78543] synonym: "PC3" EXACT [UniProtKB:P78543] xref: EMBL:AF361937 xref: EMBL:AL513326 xref: EMBL:BC105948 xref: EMBL:BC105949 xref: EMBL:U72649 xref: EMBL:Y09943 xref: HGNC:HGNC:1131 xref: UniGene:Hs.519162 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055649 ! BTG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017190 name: BTK_human def: "Tyrosine-protein kinase BTK gene" [UniProtKB:Q06187] synonym: "AGMX1" EXACT [UniProtKB:Q06187] synonym: "ATK" EXACT [UniProtKB:Q06187] synonym: "BPK" EXACT [UniProtKB:Q06187] xref: EMBL:AK057105 xref: EMBL:AL035422 xref: EMBL:BC109079 xref: EMBL:BC109080 xref: EMBL:CH471115 xref: EMBL:L31557 xref: EMBL:L31558 xref: EMBL:L31559 xref: EMBL:L31561 xref: EMBL:L31563 xref: EMBL:L31564 xref: EMBL:L31565 xref: EMBL:L31566 xref: EMBL:L31567 xref: EMBL:L31568 xref: EMBL:L31569 xref: EMBL:L31570 xref: EMBL:L31571 xref: EMBL:L31572 xref: EMBL:U10084 xref: EMBL:U10085 xref: EMBL:U10086 xref: EMBL:U10087 xref: EMBL:U13410 xref: EMBL:U13412 xref: EMBL:U13413 xref: EMBL:U13414 xref: EMBL:U13415 xref: EMBL:U13416 xref: EMBL:U13417 xref: EMBL:U13422 xref: EMBL:U13423 xref: EMBL:U13424 xref: EMBL:U13425 xref: EMBL:U13427 xref: EMBL:U13428 xref: EMBL:U13429 xref: EMBL:U13430 xref: EMBL:U13431 xref: EMBL:U13432 xref: EMBL:U13433 xref: EMBL:U78027 xref: EMBL:X58957 xref: HGNC:HGNC:1133 xref: UniGene:Hs.159494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029424 ! BTK_HUMAN relationship: codes_for CCO:B0029425 ! Q5JY90_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017191 name: CD160_human def: "CD160 antigen precursor gene" [UniProtKB:O95971] synonym: "BY55" EXACT [UniProtKB:O95971] xref: EMBL:AF060981 xref: EMBL:BC014465 xref: HGNC:HGNC:17013 xref: UniGene:Hs.488237 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054811 ! BY55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017192 name: BZW1_human def: "Basic leucine zipper and W2 domain-containing protein 1 gene" [UniProtKB:Q7L1Q6] synonym: "BZAP45" EXACT [UniProtKB:Q7L1Q6] synonym: "KIAA0005" EXACT [UniProtKB:Q7L1Q6] xref: EMBL:AC007163 xref: EMBL:BC001804 xref: EMBL:BC026303 xref: EMBL:D13630 xref: EMBL:Z70221 xref: HGNC:HGNC:18380 xref: UniGene:Hs.355983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057115 ! BZW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017193 name: C1D_human def: "Nuclear nucleic acid-binding protein C1D gene" [UniProtKB:Q13901] xref: EMBL:AC079112 xref: EMBL:AK290451 xref: EMBL:BC005235 xref: EMBL:BC009584 xref: EMBL:BC009589 xref: EMBL:BC016284 xref: EMBL:BC017884 xref: EMBL:CH471053 xref: EMBL:X95592 xref: UniGene:Hs.602900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055952 ! C1D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017194 name: C1QTNF2_human def: "Complement C1q tumor necrosis factor-related protein 2 precursor gene" [UniProtKB:Q9BXJ5] synonym: "CTRP2" EXACT [UniProtKB:Q9BXJ5] synonym: "UNQ6349/PRO21054" EXACT [UniProtKB:Q9BXJ5] xref: EMBL:AF329836 xref: EMBL:AY358839 xref: EMBL:BC011699 xref: EMBL:BC054506 xref: HGNC:HGNC:14325 xref: UniGene:Hs.110062 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058555 ! C1QT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017195 name: CC2D1A_human def: "Coiled-coil and C2 domain-containing protein 1A gene" [UniProtKB:Q6P1N0] xref: EMBL:AB097002 xref: EMBL:AF536205 xref: EMBL:AK000248 xref: EMBL:AK026371 xref: EMBL:BC048345 xref: EMBL:BC064981 xref: HGNC:HGNC:30237 xref: UniGene:Hs.269592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056880 ! C2D1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017196 name: C3AR1_human def: "C3a anaphylatoxin chemotactic receptor gene" [UniProtKB:Q16581] synonym: "AZ3B" EXACT [UniProtKB:Q16581] synonym: "C3R1" EXACT [UniProtKB:Q16581] synonym: "HNFAG09" EXACT [UniProtKB:Q16581] xref: EMBL:AB065870 xref: EMBL:AY268431 xref: EMBL:AY455929 xref: EMBL:BC020742 xref: EMBL:U28488 xref: EMBL:U62027 xref: EMBL:Z73157 xref: HGNC:HGNC:1319 xref: UniGene:Hs.591148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056154 ! C3AR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017197 name: CDC42SE1_human def: "CDC42 small effector protein 1 gene" [UniProtKB:Q9NRR8] synonym: "SPEC1" EXACT [UniProtKB:Q9NRR8] xref: EMBL:AF187845 xref: EMBL:AF286041 xref: EMBL:AF286592 xref: EMBL:AL590133 xref: EMBL:BC012796 xref: EMBL:BC041604 xref: EMBL:CH471121 xref: HGNC:HGNC:17719 xref: UniGene:Hs.22065 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058904 ! C42S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017198 name: CDC42SE2_human def: "CDC42 small effector protein 2 gene" [UniProtKB:Q9NRR3] synonym: "SPEC2" EXACT [UniProtKB:Q9NRR3] xref: EMBL:AF189692 xref: EMBL:BC096703 xref: EMBL:BC096738 xref: EMBL:BC098349 xref: EMBL:CH471062 xref: HGNC:HGNC:18547 xref: UniGene:Hs.508829 xref: UniGene:Hs.653643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058903 ! C42S2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017199 name: GPR77_human def: "C5a anaphylatoxin chemotactic receptor C5L2 gene" [UniProtKB:Q9P296] synonym: "C5L2" EXACT [UniProtKB:Q9P296] xref: EMBL:AB038237 xref: EMBL:AF317655 xref: EMBL:AY268430 xref: EMBL:BC067478 xref: HGNC:HGNC:4527 xref: UniGene:Hs.534412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059055 ! C5ARL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017200 name: C5AR1_human def: "C5a anaphylatoxin chemotactic receptor gene" [UniProtKB:P21730] synonym: "C5AR" EXACT [UniProtKB:P21730] synonym: "C5R1" EXACT [UniProtKB:P21730] xref: EMBL:AY221091 xref: EMBL:BC008982 xref: EMBL:BT007358 xref: EMBL:M62505 xref: EMBL:S56556 xref: EMBL:S56557 xref: EMBL:X57250 xref: EMBL:X58674 xref: HGNC:HGNC:1338 xref: UniGene:Hs.2161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055137 ! C5AR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017201 name: C1orf89_human def: "Miro domain-containing protein C1orf89 gene" [UniProtKB:Q9BU20] xref: EMBL:AL109627 xref: EMBL:BC002946 xref: EMBL:BC008702 xref: HGNC:HGNC:28127 xref: UniGene:Hs.546430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053922 ! A6NNY6_HUMAN relationship: codes_for CCO:B0056617 ! Q5TEV6_HUMAN relationship: codes_for CCO:B0058517 ! CA089_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017202 name: CABIN1_human def: "Calcineurin-binding protein cabin-1 gene" [UniProtKB:Q9Y6J0] synonym: "KIAA0330" EXACT [UniProtKB:Q9Y6J0] xref: EMBL:AB002328 xref: EMBL:AF072441 xref: EMBL:AP000352 xref: EMBL:AP000353 xref: EMBL:Z92546 xref: UniGene:Hs.517478 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059407 ! CABIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017203 name: CABP2_human def: "Calcium-binding protein 2 gene" [UniProtKB:Q9NPB3] xref: EMBL:AF169154 xref: EMBL:AF170811 xref: HGNC:HGNC:1385 xref: UniGene:Hs.278984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058845 ! CABP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017204 name: CABP3_human def: "Calcium-binding protein 3 gene" [UniProtKB:Q9NZU6] xref: EMBL:AF169158 xref: EMBL:AF170816 xref: EMBL:AF170817 xref: EMBL:AF170818 xref: EMBL:AF224510 xref: EMBL:AF224511 xref: HGNC:HGNC:15960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059019 ! CABP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017205 name: CABP4_human def: "Calcium-binding protein 4 gene" [UniProtKB:P57796] xref: EMBL:AC005849 xref: EMBL:AY039217 xref: EMBL:BC033167 xref: HGNC:HGNC:1386 xref: UniGene:Hs.143036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055564 ! CABP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017206 name: CABP5_human def: "Calcium-binding protein 5 gene" [UniProtKB:Q9NP86] xref: EMBL:AF169159 xref: EMBL:AF170812 xref: EMBL:AF170813 xref: EMBL:AF170814 xref: EMBL:AF170815 xref: EMBL:BC126133 xref: EMBL:BC126135 xref: HGNC:HGNC:13714 xref: UniGene:Hs.117694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058839 ! CABP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017207 name: CABYR_human def: "Calcium-binding tyrosine phosphorylation-regulated protein gene" [UniProtKB:O75952] synonym: "CBP86" EXACT [UniProtKB:O75952] synonym: "FSP2" EXACT [UniProtKB:O75952] xref: EMBL:AF088868 xref: EMBL:AF295037 xref: EMBL:AF295038 xref: EMBL:AF295039 xref: EMBL:AF329634 xref: EMBL:AY007205 xref: EMBL:BC011996 xref: HGNC:HGNC:15569 xref: UniGene:Hs.511983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054680 ! CABYR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017208 name: CACNA1D_human def: "Voltage-dependent L-type calcium channel subunit alpha-1D gene" [UniProtKB:Q01668] synonym: "CACH3" EXACT [UniProtKB:Q01668] synonym: "CACN4" EXACT [UniProtKB:Q01668] synonym: "CACNL1A2" EXACT [UniProtKB:Q01668] synonym: "CCHL1A2" EXACT [UniProtKB:Q01668] xref: EMBL:D43747 xref: EMBL:M76558 xref: EMBL:M83566 xref: HGNC:HGNC:1391 xref: UniGene:Hs.476358 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055694 ! CAC1D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017209 name: CACNA1I_human def: "Voltage-dependent T-type calcium channel subunit alpha-1I gene" [UniProtKB:Q9P0X4] synonym: "KIAA1120" EXACT [UniProtKB:Q9P0X4] xref: EMBL:AB032946 xref: EMBL:AF129133 xref: EMBL:AF142567 xref: EMBL:AF211189 xref: EMBL:AF393329 xref: EMBL:AL008716 xref: EMBL:AL022312 xref: EMBL:AL022319 xref: HGNC:HGNC:1396 xref: UniGene:Hs.125116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059035 ! CAC1I_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017210 name: CACNB3_human def: "Voltage-dependent L-type calcium channel subunit beta-3 gene" [UniProtKB:P54284] synonym: "CACNLB3" EXACT [UniProtKB:P54284] xref: EMBL:BC041811 xref: EMBL:D43704 xref: EMBL:L27584 xref: EMBL:U07139 xref: EMBL:X76555 xref: EMBL:X76556 xref: HGNC:HGNC:1403 xref: UniGene:Hs.250712 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055513 ! CACB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017211 name: CALCOCO1_human def: "Calcium-binding and coiled-coil domain-containing protein 1 gene" [UniProtKB:Q9P1Z2] synonym: "KIAA1536" EXACT [UniProtKB:Q9P1Z2] synonym: "PP13275" EXACT [UniProtKB:Q9P1Z2] synonym: "UNQ2436/PRO4996" EXACT [UniProtKB:Q9P1Z2] xref: EMBL:AB040969 xref: EMBL:AF370415 xref: EMBL:AK027881 xref: EMBL:AL136895 xref: EMBL:AY211909 xref: EMBL:AY358397 xref: EMBL:AY563137 xref: EMBL:BC003177 xref: EMBL:CH471054 xref: EMBL:CR533567 xref: HGNC:HGNC:29306 xref: UniGene:Hs.156667 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059047 ! CACO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017212 name: CDH13_human def: "Cadherin-13 precursor gene" [UniProtKB:P55290] synonym: "CDHH" EXACT [UniProtKB:P55290] xref: EMBL:AB001103 xref: EMBL:BC028624 xref: EMBL:BC030653 xref: EMBL:L34058 xref: EMBL:U59288 xref: EMBL:U59289 xref: HGNC:HGNC:1753 xref: UniGene:Hs.654386 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055534 ! CAD13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017213 name: CDH4_human def: "Cadherin-4 precursor gene" [UniProtKB:P55283] xref: EMBL:AL109911 xref: EMBL:AL162457 xref: EMBL:AL365229 xref: EMBL:AL365401 xref: EMBL:BC101651 xref: EMBL:BC112150 xref: EMBL:L34059 xref: HGNC:HGNC:1763 xref: UniGene:Hs.473231 xref: UniGene:Hs.598638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055533 ! CADH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017214 name: CA8_human def: "Carbonic anhydrase-related protein gene" [UniProtKB:P35219] synonym: "CALS" EXACT [UniProtKB:P35219] xref: EMBL:AY075022 xref: EMBL:BC069744 xref: EMBL:BC069794 xref: EMBL:BC108929 xref: EMBL:L04656 xref: HGNC:HGNC:1382 xref: UniGene:Hs.654388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055278 ! CAH8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017215 name: CALCA_human def: "Calcitonin gene-related peptide 1 precursor gene" [UniProtKB:P06881] synonym: "CALC1" EXACT [UniProtKB:P06881] xref: EMBL:BC069684 xref: EMBL:BC069704 xref: EMBL:BC069760 xref: EMBL:BC069778 xref: EMBL:BC093753 xref: EMBL:BC101599 xref: EMBL:DQ080435 xref: EMBL:K03512 xref: EMBL:K03513 xref: EMBL:M12664 xref: EMBL:M12665 xref: EMBL:M12666 xref: EMBL:M12667 xref: EMBL:M26094 xref: EMBL:M26095 xref: EMBL:M28637 xref: EMBL:M64486 xref: EMBL:X00356 xref: EMBL:X02330 xref: EMBL:X03662 xref: EMBL:X15943 xref: HGNC:HGNC:1437 xref: UniGene:Hs.37058 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054845 ! CALC_HUMAN relationship: codes_for CCO:B0054907 ! CALCA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017216 name: CALCB_human def: "Calcitonin gene-related peptide 2 precursor gene" [UniProtKB:P10092] synonym: "CALC2" EXACT [UniProtKB:P10092] xref: EMBL:BC092468 xref: EMBL:X02404 xref: EMBL:X04855 xref: EMBL:X04857 xref: EMBL:X04861 xref: HGNC:HGNC:1438 xref: UniGene:Hs.534305 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054970 ! CALCB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017217 name: CALCR_human def: "Calcitonin receptor precursor gene" [UniProtKB:P30988] xref: EMBL:AB022177 xref: EMBL:AB022178 xref: EMBL:AC003078 xref: EMBL:AK313996 xref: EMBL:AY430048 xref: EMBL:BC069611 xref: EMBL:BC075028 xref: EMBL:CH236949 xref: EMBL:CH471091 xref: EMBL:L00587 xref: EMBL:S77875 xref: EMBL:S77876 xref: EMBL:U26553 xref: EMBL:U26554 xref: EMBL:X69920 xref: EMBL:X82466 xref: HGNC:HGNC:1440 xref: UniGene:Hs.489127 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021419 ! A4D1G6_HUMAN relationship: codes_for CCO:B0055230 ! CALCR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017218 name: CALML5_human def: "Calmodulin-like protein 5 gene" [UniProtKB:Q9NZT1] synonym: "CLSP" EXACT [UniProtKB:Q9NZT1] xref: EMBL:AF172852 xref: EMBL:AL732437 xref: EMBL:BC039172 xref: HGNC:HGNC:18180 xref: UniGene:Hs.180142 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059016 ! CALL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017219 name: CALCRL_human def: "Calcitonin gene-related peptide type 1 receptor precursor gene" [UniProtKB:Q16602] synonym: "CGRPR" EXACT [UniProtKB:Q16602] xref: EMBL:AY389506 xref: EMBL:L76380 xref: EMBL:U17473 xref: HGNC:HGNC:16709 xref: UniGene:Hs.470882 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021417 ! CALRL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017220 name: CAMLG_human def: "Calcium signal-modulating cyclophilin ligand gene" [UniProtKB:P49069] synonym: "CAML" EXACT [UniProtKB:P49069] xref: EMBL:AF068179 xref: EMBL:U18242 xref: HGNC:HGNC:1471 xref: UniGene:Hs.529846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055415 ! CAMLG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017221 name: PPP3R1_human def: "Calcineurin subunit B type 1 gene" [UniProtKB:P63098] synonym: "CNA2" EXACT [UniProtKB:P63098] synonym: "CNB" EXACT [UniProtKB:P63098] xref: EMBL:AC017083 xref: EMBL:BC027913 xref: EMBL:CR456938 xref: EMBL:M30773 xref: HGNC:HGNC:9317 xref: UniGene:Hs.280604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055624 ! CANB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017222 name: CAND2_human def: "Cullin-associated NEDD8-dissociated protein 2 gene" [UniProtKB:O75155] synonym: "KIAA0667" EXACT [UniProtKB:O75155] xref: EMBL:AB014567 xref: EMBL:AC034198 xref: HGNC:HGNC:30689 xref: UniGene:Hs.343664 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054606 ! CAND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017223 name: CANT1_human def: "Soluble calcium-activated nucleotidase 1 gene" [UniProtKB:Q8WVQ1] synonym: "SHAPY" EXACT [UniProtKB:Q8WVQ1] xref: EMBL:AB097006 xref: EMBL:AB097033 xref: EMBL:AF328554 xref: EMBL:AJ312208 xref: EMBL:AK074687 xref: EMBL:BC005104 xref: EMBL:BC017655 xref: EMBL:BC065038 xref: HGNC:HGNC:19721 xref: UniGene:Hs.8859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057997 ! CANT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017224 name: AZU1_human def: "Azurocidin precursor gene" [UniProtKB:P20160] xref: EMBL:AC004799 xref: EMBL:BC044940 xref: EMBL:BC069495 xref: EMBL:BC093931 xref: EMBL:BC093933 xref: EMBL:M96326 xref: EMBL:X58794 xref: HGNC:HGNC:913 xref: UniGene:Hs.72885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055114 ! CAP7_HUMAN relationship: codes_for CCO:B0057234 ! Q86SR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017225 name: CAPG_human def: "Macrophage-capping protein gene" [UniProtKB:P40121] synonym: "AFCP" EXACT [UniProtKB:P40121] synonym: "MCP" EXACT [UniProtKB:P40121] xref: EMBL:AC062037 xref: EMBL:BC000728 xref: EMBL:BC014549 xref: EMBL:M94345 xref: EMBL:U12026 xref: HGNC:HGNC:1474 xref: UniGene:Hs.516155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055324 ! CAPG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017226 name: CAPRIN2_human def: "Caprin-2 gene" [UniProtKB:Q6IMN6] synonym: "C1QDC1" EXACT [UniProtKB:Q6IMN6] synonym: "EEG1" EXACT [UniProtKB:Q6IMN6] synonym: "KIAA1873" EXACT [UniProtKB:Q6IMN6] xref: EMBL:AC010198 xref: EMBL:AF326778 xref: EMBL:AK021453 xref: EMBL:AK026222 xref: EMBL:AY074490 xref: EMBL:AY074491 xref: EMBL:BC066295 xref: EMBL:BC111007 xref: EMBL:BC117672 xref: EMBL:BK001102 xref: EMBL:BK001103 xref: EMBL:BX538080 xref: HGNC:HGNC:21259 xref: UniGene:Hs.234355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056819 ! CAPR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017227 name: CARD10_human def: "Caspase recruitment domain-containing protein 10 gene" [UniProtKB:Q9BWT7] synonym: "CARMA3" EXACT [UniProtKB:Q9BWT7] xref: EMBL:AK074906 xref: EMBL:AL022315 xref: EMBL:AL049851 xref: EMBL:AY028896 xref: EMBL:AY032928 xref: EMBL:BC113659 xref: HGNC:HGNC:16422 xref: UniGene:Hs.57973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057563 ! Q8NC81_HUMAN relationship: codes_for CCO:B0058537 ! CAR10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017228 name: CARD11_human def: "Caspase recruitment domain-containing protein 11 gene" [UniProtKB:Q9BXL7] synonym: "CARMA1" EXACT [UniProtKB:Q9BXL7] xref: EMBL:AC004906 xref: EMBL:AF322641 xref: EMBL:AF352576 xref: EMBL:BC111719 xref: EMBL:CH236953 xref: HGNC:HGNC:16393 xref: UniGene:Hs.648101 xref: UniGene:Hs.665701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058559 ! CAR11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017229 name: CARD14_human def: "Caspase recruitment domain-containing protein 14 gene" [UniProtKB:Q9BXL6] synonym: "CARMA2" EXACT [UniProtKB:Q9BXL6] xref: EMBL:AF322642 xref: EMBL:AY032927 xref: EMBL:BC001326 xref: EMBL:BC018142 xref: HGNC:HGNC:16446 xref: UniGene:Hs.675480 xref: UniGene:Hs.696253 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058558 ! CAR14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017230 name: CARD6_human def: "Caspase recruitment domain-containing protein 6 gene" [UniProtKB:Q9BX69] xref: EMBL:AF356193 xref: EMBL:BC093825 xref: EMBL:CH471119 xref: HGNC:HGNC:16394 xref: UniGene:Hs.200242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058544 ! CARD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017231 name: CARD8_human def: "Caspase recruitment domain-containing protein 8 gene" [UniProtKB:Q9Y2G2] synonym: "KIAA0955" EXACT [UniProtKB:Q9Y2G2] synonym: "NDPP1" EXACT [UniProtKB:Q9Y2G2] xref: EMBL:AB023172 xref: EMBL:AF322184 xref: EMBL:AF331519 xref: EMBL:AF405558 xref: EMBL:AF511652 xref: EMBL:AY026322 xref: EMBL:BC045539 xref: EMBL:BC056891 xref: HGNC:HGNC:17057 xref: UniGene:Hs.446146 xref: UniGene:Hs.655940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056313 ! Q4G0N6_HUMAN relationship: codes_for CCO:B0059303 ! CARD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017232 name: CARD9_human def: "Caspase recruitment domain-containing protein 9 gene" [UniProtKB:Q9H257] xref: EMBL:AF311287 xref: EMBL:AK024001 xref: EMBL:AL592301 xref: EMBL:BC008877 xref: HGNC:HGNC:16391 xref: UniGene:Hs.694071 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058679 ! CARD9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017233 name: CARM1_human def: "Histone-arginine methyltransferase CARM1 gene" [UniProtKB:Q86X55] synonym: "PRMT4" EXACT [UniProtKB:Q86X55] xref: EMBL:AL833242 xref: EMBL:BC046240 xref: EMBL:BU176535 xref: HGNC:HGNC:23393 xref: UniGene:Hs.371416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057284 ! CARM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017234 name: CARTPT_human def: "Cocaine- and amphetamine-regulated transcript protein precursor gene" [UniProtKB:Q16568] synonym: "CART" EXACT [UniProtKB:Q16568] xref: EMBL:BC029882 xref: EMBL:U16826 xref: EMBL:U20325 xref: HGNC:HGNC:24323 xref: UniGene:Hs.1707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056152 ! CART_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017235 name: CASP2_human def: "Caspase-2 precursor gene" [UniProtKB:P42575] synonym: "ICH1" EXACT [UniProtKB:P42575] synonym: "NEDD2" EXACT [UniProtKB:P42575] xref: EMBL:AB209640 xref: EMBL:AC073342 xref: EMBL:AF314174 xref: EMBL:AF314175 xref: EMBL:AY219042 xref: EMBL:BC002427 xref: EMBL:BT007240 xref: EMBL:CR541748 xref: EMBL:U13021 xref: EMBL:U13022 xref: HGNC:HGNC:1503 xref: UniGene:Hs.368982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055352 ! CASP2_HUMAN relationship: codes_for CCO:B0058603 ! Q9BZL0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017236 name: CASP3_human def: "Caspase-3 precursor gene" [UniProtKB:P42574] synonym: "CPP32" EXACT [UniProtKB:P42574] xref: EMBL:AJ413269 xref: EMBL:AY219866 xref: EMBL:BC016926 xref: EMBL:U13737 xref: EMBL:U13738 xref: EMBL:U26943 xref: HGNC:HGNC:1504 xref: UniGene:Hs.141125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055351 ! CASP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017237 name: CASP6_human def: "Caspase-6 precursor gene" [UniProtKB:P55212] synonym: "MCH2" EXACT [UniProtKB:P55212] xref: EMBL:AY254046 xref: EMBL:BC000305 xref: EMBL:BC004460 xref: EMBL:U20536 xref: EMBL:U20537 xref: HGNC:HGNC:1507 xref: UniGene:Hs.654616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055531 ! CASP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017238 name: CASP7_human def: "Caspase-7 precursor gene" [UniProtKB:P55210] synonym: "MCH3" EXACT [UniProtKB:P55210] xref: EMBL:AL592546 xref: EMBL:AL627395 xref: EMBL:BC015799 xref: EMBL:CH471066 xref: EMBL:U37448 xref: EMBL:U37449 xref: EMBL:U39613 xref: EMBL:U40281 xref: EMBL:U67206 xref: EMBL:U67319 xref: EMBL:U67320 xref: HGNC:HGNC:1508 xref: UniGene:Hs.9216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055530 ! CASP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017239 name: CASP8_human def: "Caspase-8 precursor gene" [UniProtKB:Q14790] synonym: "MCH5" EXACT [UniProtKB:Q14790] xref: EMBL:AB038985 xref: EMBL:AC007256 xref: EMBL:AC007283 xref: EMBL:AF009620 xref: EMBL:AF102139 xref: EMBL:AF102140 xref: EMBL:AF102141 xref: EMBL:AF102142 xref: EMBL:AF102143 xref: EMBL:AF102144 xref: EMBL:AF102145 xref: EMBL:AF102146 xref: EMBL:AF380342 xref: EMBL:AF422925 xref: EMBL:AF422926 xref: EMBL:AF422927 xref: EMBL:AF422928 xref: EMBL:AF422929 xref: EMBL:BC028223 xref: EMBL:DQ355026 xref: EMBL:U58143 xref: EMBL:U60520 xref: EMBL:X98172 xref: EMBL:X98173 xref: EMBL:X98174 xref: EMBL:X98175 xref: EMBL:X98176 xref: EMBL:X98177 xref: EMBL:X98178 xref: HGNC:HGNC:1509 xref: UniGene:Hs.655983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026578 ! A8MU92_HUMAN relationship: codes_for CCO:B0056014 ! CASP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017240 name: CASP10_human def: "Caspase-10 precursor gene" [UniProtKB:Q92851] synonym: "MCH4" EXACT [UniProtKB:Q92851] xref: EMBL:AB038979 xref: EMBL:AC007283 xref: EMBL:AF111344 xref: EMBL:AF111345 xref: EMBL:AJ487678 xref: EMBL:AJ487679 xref: EMBL:AY690601 xref: EMBL:BC042844 xref: EMBL:CH471063 xref: EMBL:EF050529 xref: EMBL:U60519 xref: EMBL:U86214 xref: HGNC:HGNC:1500 xref: UniGene:Hs.5353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056711 ! Q68HC0_HUMAN relationship: codes_for CCO:B0056835 ! Q6KF62_HUMAN relationship: codes_for CCO:B0056836 ! Q6KF63_HUMAN relationship: codes_for CCO:B0057326 ! Q8IUP5_HUMAN relationship: codes_for CCO:B0058106 ! CASPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017241 name: CASR_human def: "Extracellular calcium-sensing receptor precursor gene" [UniProtKB:P41180] synonym: "GPRC2A" EXACT [UniProtKB:P41180] synonym: "PCAR1" EXACT [UniProtKB:P41180] xref: EMBL:BC104999 xref: EMBL:BC112236 xref: EMBL:D50855 xref: EMBL:DQ088967 xref: EMBL:S68032 xref: EMBL:S68033 xref: EMBL:S68036 xref: EMBL:S79217 xref: EMBL:S81755 xref: EMBL:S83176 xref: EMBL:U20759 xref: EMBL:U20760 xref: EMBL:X81086 xref: HGNC:HGNC:1514 xref: UniGene:Hs.435615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055335 ! CASR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017242 name: CASZ1_human def: "Zinc finger protein castor homolog 1 gene" [UniProtKB:Q86V15] synonym: "CST" EXACT [UniProtKB:Q86V15] synonym: "SRG" EXACT [UniProtKB:Q86V15] synonym: "ZNF693" EXACT [UniProtKB:Q86V15] xref: EMBL:AK000328 xref: EMBL:AL139423 xref: EMBL:BC004410 xref: EMBL:BC051883 xref: EMBL:DQ217660 xref: HGNC:HGNC:26002 xref: UniGene:Hs.439894 xref: UniGene:Hs.703785 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057260 ! CASZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017243 name: CAT_human def: "Catalase gene" [UniProtKB:P04040] xref: EMBL:AK291585 xref: EMBL:AK315350 xref: EMBL:AL035079 xref: EMBL:AY028632 xref: EMBL:AY545477 xref: EMBL:BC110398 xref: EMBL:BC112217 xref: EMBL:BC112219 xref: EMBL:CH471064 xref: EMBL:K02400 xref: EMBL:L13609 xref: EMBL:X04076 xref: EMBL:X04085 xref: EMBL:X04086 xref: EMBL:X04087 xref: EMBL:X04088 xref: EMBL:X04089 xref: EMBL:X04090 xref: EMBL:X04091 xref: EMBL:X04092 xref: EMBL:X04093 xref: EMBL:X04094 xref: EMBL:X04095 xref: EMBL:X04096 xref: HGNC:HGNC:1516 xref: UniGene:Hs.502302 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019335 ! CATA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017244 name: CAV3_human def: "Caveolin-3 gene" [UniProtKB:P56539] xref: EMBL:AF036365 xref: EMBL:AF036366 xref: EMBL:AF036367 xref: EMBL:AF043101 xref: EMBL:BC069368 xref: EMBL:BC102033 xref: EMBL:BC102036 xref: EMBL:BC102037 xref: EMBL:Y14747 xref: HGNC:HGNC:1529 xref: UniGene:Hs.98303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055545 ! CAV3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017245 name: CAPS_human def: "Calcyphosin gene" [UniProtKB:Q13938] xref: EMBL:AC004602 xref: EMBL:BC080599 xref: EMBL:BC101513 xref: EMBL:BC104766 xref: EMBL:X97966 xref: HGNC:HGNC:1487 xref: UniGene:Hs.584744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055953 ! CAYP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017246 name: C2orf29_human def: "Uncharacterized protein C2orf29 gene" [UniProtKB:Q9UKZ1] synonym: "C40" EXACT [UniProtKB:Q9UKZ1] xref: EMBL:AC013722 xref: EMBL:AF103798 xref: EMBL:BC018664 xref: EMBL:BC064421 xref: HGNC:HGNC:25217 xref: UniGene:Hs.593973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059210 ! CB029_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017247 name: CBLC_human def: "Signal transduction protein CBL-C gene" [UniProtKB:Q9ULV8] synonym: "CBL3" EXACT [UniProtKB:Q9ULV8] synonym: "RNF57" EXACT [UniProtKB:Q9ULV8] xref: EMBL:AB028645 xref: EMBL:AF117646 xref: EMBL:AF117647 xref: EMBL:BC028915 xref: HGNC:HGNC:15961 xref: UniGene:Hs.466907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059234 ! CBLC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017248 name: CBX2_human def: "Chromobox protein homolog 2 gene" [UniProtKB:Q14781] xref: EMBL:AC105337 xref: EMBL:BC004252 xref: EMBL:X77824 xref: HGNC:HGNC:1552 xref: UniGene:Hs.368410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056013 ! CBX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017249 name: CBX3_human def: "Chromobox protein homolog 3 gene" [UniProtKB:Q13185] xref: EMBL:AB030905 xref: EMBL:AF136630 xref: EMBL:BC000954 xref: EMBL:BC014380 xref: EMBL:U26312 xref: HGNC:HGNC:1553 xref: UniGene:Hs.381189 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055884 ! CBX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017250 name: CBX4_human def: "E3 SUMO-protein ligase CBX4 gene" [UniProtKB:O00257] xref: EMBL:AF013956 xref: EMBL:BC014967 xref: EMBL:U94344 xref: HGNC:HGNC:1554 xref: UniGene:Hs.405046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054304 ! CBX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017251 name: CBX6_human def: "Chromobox protein homolog 6 gene" [UniProtKB:O95503] xref: EMBL:AL008583 xref: EMBL:BC012111 xref: EMBL:BC064900 xref: HGNC:HGNC:1556 xref: UniGene:Hs.592201 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054770 ! CBX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017252 name: CBX7_human def: "Chromobox protein homolog 7 gene" [UniProtKB:O95931] xref: EMBL:AL031846 xref: EMBL:BC051773 xref: HGNC:HGNC:1557 xref: UniGene:Hs.356416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054805 ! CBX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017253 name: CBX8_human def: "Chromobox protein homolog 8 gene" [UniProtKB:Q9HC52] synonym: "PC3" EXACT [UniProtKB:Q9HC52] synonym: "RC1" EXACT [UniProtKB:Q9HC52] xref: EMBL:AF174482 xref: EMBL:AF266479 xref: EMBL:AK074560 xref: EMBL:BC008937 xref: EMBL:BC009376 xref: EMBL:BC019289 xref: HGNC:HGNC:15962 xref: UniGene:Hs.387258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058797 ! CBX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017254 name: CBY1_human def: "Protein chibby homolog 1 gene" [UniProtKB:Q9Y3M2] synonym: "ARB1" EXACT [UniProtKB:Q9Y3M2] synonym: "C22orf2" EXACT [UniProtKB:Q9Y3M2] synonym: "CBY" EXACT [UniProtKB:Q9Y3M2] synonym: "HRIHFB2025" EXACT [UniProtKB:Q9Y3M2] synonym: "PGEA1" EXACT [UniProtKB:Q9Y3M2] xref: EMBL:AB015347 xref: EMBL:AB111855 xref: EMBL:AF331041 xref: EMBL:AL021707 xref: EMBL:AL050345 xref: EMBL:AL136686 xref: EMBL:BC016139 xref: EMBL:BK005534 xref: EMBL:CH471095 xref: EMBL:CR456410 xref: HGNC:HGNC:1307 xref: UniGene:Hs.334911 xref: UniGene:Hs.596584 xref: UniGene:Hs.700647 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059339 ! CBY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017255 name: CCDC111_human def: "Coiled-coil domain-containing protein 111 gene" [UniProtKB:Q96LW4] xref: EMBL:AK057729 xref: EMBL:BC064600 xref: EMBL:BX647575 xref: HGNC:HGNC:26575 xref: UniGene:Hs.481307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058275 ! CC111_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017256 name: CCBP2_human def: "Chemokine-binding protein 2 gene" [UniProtKB:O00590] synonym: "CCR10" EXACT [UniProtKB:O00590] synonym: "CMKBR9" EXACT [UniProtKB:O00590] xref: EMBL:AY262687 xref: EMBL:BC008816 xref: EMBL:BC011631 xref: EMBL:BC020558 xref: EMBL:BC101629 xref: EMBL:BC112045 xref: EMBL:BT006800 xref: EMBL:U94888 xref: EMBL:Y12815 xref: HGNC:HGNC:1565 xref: UniGene:Hs.146346 xref: UniGene:Hs.656856 xref: UniGene:Hs.706232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054335 ! CCBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017257 name: CCDC79_human def: "Coiled-coil domain-containing protein 79 gene" [UniProtKB:Q8NA31] xref: EMBL:AC044802 xref: EMBL:AK093213 xref: EMBL:BC126109 xref: HGNC:HGNC:26675 xref: UniGene:Hs.699031 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057543 ! CCD79_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017258 name: CCKAR_human def: "Cholecystokinin receptor type A gene" [UniProtKB:P32238] synonym: "CCKRA" EXACT [UniProtKB:P32238] xref: EMBL:AY322549 xref: EMBL:BC074987 xref: EMBL:D85606 xref: EMBL:L13605 xref: EMBL:L19315 xref: EMBL:U23427 xref: EMBL:U23428 xref: EMBL:U23429 xref: EMBL:U23430 xref: HGNC:HGNC:1570 xref: UniGene:Hs.129 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055251 ! CCKAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017259 name: CCK_human def: "Cholecystokinin precursor gene" [UniProtKB:P06307] xref: EMBL:AY514491 xref: EMBL:BC008283 xref: EMBL:BT006991 xref: EMBL:L00354 xref: HGNC:HGNC:1569 xref: UniGene:Hs.458426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054903 ! CCKN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017260 name: CCL14_human def: "C-C motif chemokine 14 precursor gene" [UniProtKB:Q16627] synonym: "NCC2" EXACT [UniProtKB:Q16627] synonym: "SCYA14" EXACT [UniProtKB:Q16627] xref: EMBL:AF088219 xref: EMBL:BC038289 xref: EMBL:BC045165 xref: EMBL:Z49269 xref: EMBL:Z49270 xref: EMBL:Z70292 xref: EMBL:Z70293 xref: HGNC:HGNC:10612 xref: UniGene:Hs.272493 xref: UniGene:Hs.656286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056164 ! CCL14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017261 name: CCL15_human def: "C-C motif chemokine 15 precursor gene" [UniProtKB:Q16663] synonym: "MIP5" EXACT [UniProtKB:Q16663] synonym: "NCC3" EXACT [UniProtKB:Q16663] synonym: "SCYA15" EXACT [UniProtKB:Q16663] xref: EMBL:AF031587 xref: EMBL:AF088219 xref: EMBL:U58914 xref: EMBL:Z70292 xref: EMBL:Z70293 xref: HGNC:HGNC:10613 xref: UniGene:Hs.656286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056171 ! CCL15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017262 name: CCL17_human def: "C-C motif chemokine 17 precursor gene" [UniProtKB:Q92583] synonym: "SCYA17" EXACT [UniProtKB:Q92583] synonym: "TARC" EXACT [UniProtKB:Q92583] xref: EMBL:AC004382 xref: EMBL:BC069107 xref: EMBL:BC112066 xref: EMBL:BC112068 xref: EMBL:D43767 xref: HGNC:HGNC:10615 xref: UniGene:Hs.546294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058067 ! CCL17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017263 name: CCL19_human def: "C-C motif chemokine 19 precursor gene" [UniProtKB:Q99731] synonym: "ELC" EXACT [UniProtKB:Q99731] synonym: "MIP3B" EXACT [UniProtKB:Q99731] synonym: "SCYA19" EXACT [UniProtKB:Q99731] xref: EMBL:AB000887 xref: EMBL:AJ223410 xref: EMBL:BC027968 xref: EMBL:U77180 xref: EMBL:U88321 xref: HGNC:HGNC:10617 xref: UniGene:Hs.50002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058448 ! CCL19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017264 name: CCL1_human def: "C-C motif chemokine 1 precursor gene" [UniProtKB:P22362] synonym: "SCYA1" EXACT [UniProtKB:P22362] xref: EMBL:BC105073 xref: EMBL:BC105075 xref: EMBL:M57502 xref: EMBL:M57506 xref: HGNC:HGNC:10609 xref: UniGene:Hs.72918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055144 ! CCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017265 name: CCL20_human def: "C-C motif chemokine 20 precursor gene" [UniProtKB:P78556] synonym: "LARC" EXACT [UniProtKB:P78556] synonym: "MIP3A" EXACT [UniProtKB:P78556] synonym: "SCYA20" EXACT [UniProtKB:P78556] xref: EMBL:AC073065 xref: EMBL:BC020698 xref: EMBL:D86955 xref: EMBL:U64197 xref: EMBL:U77035 xref: HGNC:HGNC:10619 xref: UniGene:Hs.75498 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055653 ! CCL20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017266 name: CCL21_human def: "C-C motif chemokine 21 precursor gene" [UniProtKB:O00585] synonym: "SCYA21" EXACT [UniProtKB:O00585] synonym: "UNQ784/PRO1600" EXACT [UniProtKB:O00585] xref: EMBL:AB002409 xref: EMBL:AF001979 xref: EMBL:AJ005654 xref: EMBL:AY358887 xref: EMBL:BC027918 xref: EMBL:U88320 xref: HGNC:HGNC:10620 xref: UniGene:Hs.57907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054334 ! CCL21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017267 name: CCL22_human def: "C-C motif chemokine 22 precursor gene" [UniProtKB:O00626] synonym: "A-152E5.1" EXACT [UniProtKB:O00626] synonym: "MDC" EXACT [UniProtKB:O00626] synonym: "SCYA22" EXACT [UniProtKB:O00626] xref: EMBL:AC004382 xref: EMBL:BC027952 xref: EMBL:U83171 xref: EMBL:U83239 xref: HGNC:HGNC:10621 xref: UniGene:Hs.534347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054338 ! CCL22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017268 name: CCL23_human def: "C-C motif chemokine 23 precursor gene" [UniProtKB:P55773] synonym: "MIP3" EXACT [UniProtKB:P55773] synonym: "MPIF1" EXACT [UniProtKB:P55773] synonym: "SCYA23" EXACT [UniProtKB:P55773] xref: EMBL:AF088219 xref: EMBL:BC093970 xref: EMBL:U58913 xref: EMBL:U67128 xref: EMBL:U85767 xref: HGNC:HGNC:10622 xref: UniGene:Hs.169191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055537 ! CCL23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017269 name: CCL24_human def: "C-C motif chemokine 24 precursor gene" [UniProtKB:O00175] synonym: "MPIF2" EXACT [UniProtKB:O00175] synonym: "SCYA24" EXACT [UniProtKB:O00175] xref: EMBL:AC005102 xref: EMBL:AJ223461 xref: EMBL:BC069072 xref: EMBL:BC069391 xref: EMBL:U85768 xref: HGNC:HGNC:10623 xref: UniGene:Hs.247838 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054295 ! CCL24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017270 name: CCL25_human def: "C-C motif chemokine 25 precursor gene" [UniProtKB:O15444] synonym: "SCYA25" EXACT [UniProtKB:O15444] synonym: "TECK" EXACT [UniProtKB:O15444] xref: EMBL:AB046579 xref: EMBL:BC130561 xref: EMBL:CH471139 xref: EMBL:U86358 xref: HGNC:HGNC:10624 xref: UniGene:Hs.310511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054436 ! CCL25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017271 name: CCL26_human def: "C-C motif chemokine 26 precursor gene" [UniProtKB:Q9Y258] synonym: "SCYA26" EXACT [UniProtKB:Q9Y258] synonym: "UNQ216/PRO242" EXACT [UniProtKB:Q9Y258] xref: EMBL:AB010447 xref: EMBL:AB016542 xref: EMBL:AC005102 xref: EMBL:AF096296 xref: EMBL:AF124601 xref: EMBL:AF142434 xref: EMBL:AY358893 xref: EMBL:BC069394 xref: EMBL:BC093773 xref: EMBL:BC101665 xref: HGNC:HGNC:10625 xref: UniGene:Hs.131342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059292 ! CCL26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017272 name: CCL3_human def: "C-C motif chemokine 3 precursor gene" [UniProtKB:P10147] synonym: "G0S19-1" EXACT [UniProtKB:P10147] synonym: "MIP1A" EXACT [UniProtKB:P10147] synonym: "SCYA3" EXACT [UniProtKB:P10147] xref: EMBL:AF043339 xref: EMBL:BC071834 xref: EMBL:D00044 xref: EMBL:D90144 xref: EMBL:M23178 xref: EMBL:M23452 xref: EMBL:M25315 xref: EMBL:X03754 xref: EMBL:X04018 xref: HGNC:HGNC:10627 xref: UniGene:Hs.514107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054972 ! CCL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017273 name: CCL4_human def: "C-C motif chemokine 4 precursor gene" [UniProtKB:P13236] synonym: "LAG1" EXACT [UniProtKB:P13236] synonym: "MIP1B" EXACT [UniProtKB:P13236] synonym: "SCYA4" EXACT [UniProtKB:P13236] xref: EMBL:AC003976 xref: EMBL:AY766446 xref: EMBL:AY766459 xref: EMBL:BC104226 xref: EMBL:BC104227 xref: EMBL:BC107433 xref: EMBL:CR542119 xref: EMBL:J04130 xref: EMBL:M23502 xref: EMBL:M25316 xref: EMBL:M57503 xref: EMBL:M69201 xref: EMBL:M69202 xref: EMBL:M69203 xref: EMBL:X16166 xref: EMBL:X53682 xref: EMBL:X53683 xref: HGNC:HGNC:10630 xref: UniGene:Hs.648241 xref: UniGene:Hs.655293 xref: UniGene:Hs.661942 xref: UniGene:Hs.75703 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055011 ! CCL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017274 name: CCL5_human def: "C-C motif chemokine 5 precursor gene" [UniProtKB:P13501] synonym: "D17S136E" EXACT [UniProtKB:P13501] synonym: "SCYA5" EXACT [UniProtKB:P13501] xref: EMBL:AF043341 xref: EMBL:AF088219 xref: EMBL:AF266753 xref: EMBL:BC008600 xref: EMBL:DQ017060 xref: EMBL:DQ230537 xref: EMBL:M21121 xref: HGNC:HGNC:10632 xref: UniGene:Hs.514821 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055013 ! CCL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017275 name: CCM2_human def: "Malcavernin gene" [UniProtKB:Q9BSQ5] synonym: "C7orf22" EXACT [UniProtKB:Q9BSQ5] synonym: "PP10187" EXACT [UniProtKB:Q9BSQ5] xref: EMBL:AF370392 xref: EMBL:AK098005 xref: EMBL:BC004903 xref: EMBL:BC008859 xref: EMBL:BC016832 xref: EMBL:BC025958 xref: HGNC:HGNC:21708 xref: UniGene:Hs.148272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058509 ! CCM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017276 name: CCR1_human def: "C-C chemokine receptor type 1 gene" [UniProtKB:P32246] synonym: "CMKBR1" EXACT [UniProtKB:P32246] synonym: "CMKR1" EXACT [UniProtKB:P32246] synonym: "SCYAR1" EXACT [UniProtKB:P32246] xref: EMBL:BC051306 xref: EMBL:BC064991 xref: EMBL:D10925 xref: EMBL:L09230 xref: EMBL:L10918 xref: HGNC:HGNC:1602 xref: UniGene:Hs.301921 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055256 ! CCR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017277 name: CCR2_human def: "C-C chemokine receptor type 2 gene" [UniProtKB:P41597] synonym: "CMKBR2" EXACT [UniProtKB:P41597] xref: EMBL:AF545480 xref: EMBL:BC074751 xref: EMBL:BC126452 xref: EMBL:D29984 xref: EMBL:U03882 xref: EMBL:U03905 xref: EMBL:U80924 xref: EMBL:U95626 xref: HGNC:HGNC:1603 xref: UniGene:Hs.511794 xref: UniGene:Hs.644637 xref: UniGene:Hs.705362 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055344 ! CCR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017278 name: CCR3_human def: "C-C chemokine receptor type 3 gene" [UniProtKB:P51677] synonym: "CMKBR3" EXACT [UniProtKB:P51677] xref: EMBL:AB023887 xref: EMBL:AF026535 xref: EMBL:AF247361 xref: EMBL:AF262299 xref: EMBL:AF262301 xref: EMBL:AY221092 xref: EMBL:BC110297 xref: EMBL:BC130318 xref: EMBL:BC130320 xref: EMBL:EF064760 xref: EMBL:U28694 xref: EMBL:U49727 xref: EMBL:U51241 xref: HGNC:HGNC:1604 xref: UniGene:Hs.506190 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055472 ! CCR3_HUMAN relationship: codes_for CCO:B0057929 ! Q8TDP6_HUMAN relationship: codes_for CCO:B0057930 ! Q8TDP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017279 name: CCR4_human def: "C-C chemokine receptor type 4 gene" [UniProtKB:P51679] synonym: "CMKBR4" EXACT [UniProtKB:P51679] xref: EMBL:AB023888 xref: EMBL:AB023889 xref: EMBL:AB023890 xref: EMBL:AB023891 xref: EMBL:AB023892 xref: EMBL:AY322539 xref: EMBL:BC069139 xref: EMBL:BC071751 xref: EMBL:BC074935 xref: EMBL:X85740 xref: HGNC:HGNC:1605 xref: UniGene:Hs.184926 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055473 ! CCR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017280 name: CCR5_human def: "C-C chemokine receptor type 5 gene" [UniProtKB:P51681] synonym: "CMKBR5" EXACT [UniProtKB:P51681] xref: EMBL:AF011500 xref: EMBL:AF011501 xref: EMBL:AF011502 xref: EMBL:AF011503 xref: EMBL:AF011504 xref: EMBL:AF011505 xref: EMBL:AF011506 xref: EMBL:AF011507 xref: EMBL:AF011508 xref: EMBL:AF011509 xref: EMBL:AF011510 xref: EMBL:AF011511 xref: EMBL:AF011512 xref: EMBL:AF011513 xref: EMBL:AF011514 xref: EMBL:AF011515 xref: EMBL:AF011516 xref: EMBL:AF011517 xref: EMBL:AF011518 xref: EMBL:AF011519 xref: EMBL:AF011520 xref: EMBL:AF011521 xref: EMBL:AF011522 xref: EMBL:AF011523 xref: EMBL:AF011524 xref: EMBL:AF011525 xref: EMBL:AF011526 xref: EMBL:AF011527 xref: EMBL:AF011528 xref: EMBL:AF011529 xref: EMBL:AF011530 xref: EMBL:AF011531 xref: EMBL:AF011532 xref: EMBL:AF011533 xref: EMBL:AF011534 xref: EMBL:AF011535 xref: EMBL:AF011536 xref: EMBL:AF011537 xref: EMBL:AF031237 xref: EMBL:AF052539 xref: EMBL:AY221093 xref: EMBL:BC038398 xref: EMBL:U54994 xref: EMBL:U57840 xref: EMBL:U83326 xref: EMBL:U95626 xref: EMBL:X91492 xref: HGNC:HGNC:1606 xref: UniGene:Hs.450802 xref: UniGene:Hs.536735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054368 ! O14694_HUMAN relationship: codes_for CCO:B0055474 ! CCR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017281 name: CCR6_human def: "C-C chemokine receptor type 6 gene" [UniProtKB:P51684] synonym: "CKRL3" EXACT [UniProtKB:P51684] synonym: "CMKBR6" EXACT [UniProtKB:P51684] synonym: "GPR29" EXACT [UniProtKB:P51684] synonym: "STRL22" EXACT [UniProtKB:P51684] xref: EMBL:AL121935 xref: EMBL:AY242126 xref: EMBL:BC037960 xref: EMBL:U45984 xref: EMBL:U60000 xref: EMBL:U68030 xref: EMBL:U68032 xref: EMBL:Z79784 xref: HGNC:HGNC:1607 xref: UniGene:Hs.46468 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055475 ! CCR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017282 name: CCR7_human def: "C-C chemokine receptor type 7 precursor gene" [UniProtKB:P32248] synonym: "CMKBR7" EXACT [UniProtKB:P32248] synonym: "EBI1" EXACT [UniProtKB:P32248] synonym: "EVI1" EXACT [UniProtKB:P32248] xref: EMBL:AY587876 xref: EMBL:BC035343 xref: EMBL:L08176 xref: EMBL:L31581 xref: EMBL:L31582 xref: EMBL:L31583 xref: EMBL:L31584 xref: HGNC:HGNC:1608 xref: UniGene:Hs.370036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055258 ! CCR7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017283 name: CCR8_human def: "C-C chemokine receptor type 8 gene" [UniProtKB:P51685] synonym: "CKRL1" EXACT [UniProtKB:P51685] synonym: "CMKBR8" EXACT [UniProtKB:P51685] synonym: "CMKBRL2" EXACT [UniProtKB:P51685] xref: EMBL:AF005210 xref: EMBL:BC069067 xref: EMBL:BC074743 xref: EMBL:BC107159 xref: EMBL:D49919 xref: EMBL:U45983 xref: EMBL:U62556 xref: EMBL:Y08456 xref: EMBL:Z79782 xref: HGNC:HGNC:1609 xref: UniGene:Hs.113222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055476 ! CCR8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017284 name: CCR9_human def: "C-C chemokine receptor type 9 gene" [UniProtKB:P51686] synonym: "CMKBR9" EXACT [UniProtKB:P51686] synonym: "GPR28" EXACT [UniProtKB:P51686] xref: EMBL:AF145439 xref: EMBL:AF145440 xref: EMBL:AJ132337 xref: EMBL:AY242127 xref: EMBL:BC069678 xref: EMBL:BC095516 xref: EMBL:U45982 xref: HGNC:HGNC:1610 xref: UniGene:Hs.225946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055477 ! CCR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017285 name: CCRL2_human def: "C-C chemokine receptor-like 2 gene" [UniProtKB:O00421] synonym: "CCR11" EXACT [UniProtKB:O00421] synonym: "CCR6" EXACT [UniProtKB:O00421] synonym: "CKRX" EXACT [UniProtKB:O00421] synonym: "CRAM" EXACT [UniProtKB:O00421] synonym: "HCR" EXACT [UniProtKB:O00421] xref: EMBL:AF014958 xref: EMBL:AF015524 xref: EMBL:AF015525 xref: EMBL:AJ344142 xref: EMBL:AY337001 xref: EMBL:BC025717 xref: EMBL:BC071682 xref: EMBL:BC096075 xref: EMBL:BC096076 xref: EMBL:BC099623 xref: EMBL:U95626 xref: EMBL:U97123 xref: HGNC:HGNC:1612 xref: UniGene:Hs.535713 xref: UniGene:Hs.617040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054318 ! CCRL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017286 name: CD14_human def: "Monocyte differentiation antigen CD14 precursor gene" [UniProtKB:P08571] xref: EMBL:AF097942 xref: EMBL:AY044269 xref: EMBL:BC010507 xref: EMBL:M86511 xref: EMBL:X06882 xref: EMBL:X13334 xref: HGNC:HGNC:1628 xref: UniGene:Hs.163867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054928 ! CD14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017287 name: CD19_human def: "B-lymphocyte antigen CD19 precursor gene" [UniProtKB:P15391] xref: EMBL:AB052799 xref: EMBL:BC006338 xref: EMBL:M21097 xref: EMBL:M28170 xref: EMBL:M62544 xref: EMBL:M62545 xref: EMBL:M62546 xref: EMBL:M62547 xref: EMBL:M62548 xref: EMBL:M62549 xref: EMBL:M62550 xref: EMBL:M84371 xref: HGNC:HGNC:1633 xref: UniGene:Hs.652262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055035 ! CD19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017288 name: CD209_human def: "CD209 antigen gene" [UniProtKB:Q9NNX6] synonym: "CLEC4L" EXACT [UniProtKB:Q9NNX6] xref: EMBL:AF209479 xref: EMBL:AF290886 xref: EMBL:AY042221 xref: EMBL:AY042222 xref: EMBL:AY042223 xref: EMBL:AY042224 xref: EMBL:AY042225 xref: EMBL:AY042226 xref: EMBL:AY042227 xref: EMBL:AY042228 xref: EMBL:AY042229 xref: EMBL:AY042230 xref: EMBL:AY042231 xref: EMBL:AY042232 xref: EMBL:AY042233 xref: EMBL:M98457 xref: HGNC:HGNC:1641 xref: UniGene:Hs.278694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058829 ! CD209_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017289 name: MS4A1_human def: "B-lymphocyte antigen CD20 gene" [UniProtKB:P11836] synonym: "CD20" EXACT [UniProtKB:P11836] xref: EMBL:AP003127 xref: EMBL:BC002807 xref: EMBL:CH471076 xref: EMBL:L23415 xref: EMBL:L23416 xref: EMBL:L23417 xref: EMBL:L23419 xref: EMBL:M27394 xref: EMBL:M27395 xref: EMBL:X07203 xref: EMBL:X07204 xref: EMBL:X12530 xref: HGNC:HGNC:7315 xref: UniGene:Hs.438040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054995 ! CD20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017290 name: CD226_human def: "CD226 antigen precursor gene" [UniProtKB:Q15762] synonym: "DNAM1" EXACT [UniProtKB:Q15762] xref: EMBL:AJ537553 xref: EMBL:BC074787 xref: EMBL:U56102 xref: HGNC:HGNC:16961 xref: UniGene:Hs.660130 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056106 ! CD226_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017291 name: CD244_human def: "Natural killer cell receptor 2B4 precursor gene" [UniProtKB:Q9BZW8] synonym: "2B4" EXACT [UniProtKB:Q9BZW8] xref: EMBL:AF105261 xref: EMBL:AF107761 xref: EMBL:AF117711 xref: EMBL:AF145782 xref: EMBL:AF242540 xref: EMBL:AF363452 xref: EMBL:AJ245375 xref: EMBL:AJ245376 xref: EMBL:AJ245377 xref: EMBL:BC028073 xref: EMBL:BC053985 xref: HGNC:HGNC:18171 xref: UniGene:Hs.157872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058610 ! CD244_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017292 name: CD24_human def: "Signal transducer CD24 precursor gene" [UniProtKB:P25063] synonym: "CD24A" EXACT [UniProtKB:P25063] xref: EMBL:BC064619 xref: EMBL:BT007404 xref: EMBL:L33930 xref: EMBL:M58664 xref: EMBL:S75311 xref: EMBL:X69397 xref: HGNC:HGNC:1645 xref: UniGene:Hs.644105 xref: UniGene:Hs.694721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055177 ! CD24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017293 name: CD276_human def: "CD276 antigen precursor gene" [UniProtKB:Q5ZPR3] synonym: "B7H3" EXACT [UniProtKB:Q5ZPR3] synonym: "PSEC0249" EXACT [UniProtKB:Q5ZPR3] synonym: "UNQ309/PRO352" EXACT [UniProtKB:Q5ZPR3] xref: EMBL:AF302102 xref: EMBL:AJ583695 xref: EMBL:AK074849 xref: EMBL:AK074997 xref: EMBL:AK075549 xref: EMBL:AY358343 xref: EMBL:BC062581 xref: HGNC:HGNC:19137 xref: UniGene:Hs.77873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056685 ! CD276_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017294 name: CD27_human def: "CD27 antigen precursor gene" [UniProtKB:P26842] synonym: "TNFRSF7" EXACT [UniProtKB:P26842] xref: EMBL:AY504961 xref: EMBL:BC012160 xref: EMBL:M63928 xref: HGNC:HGNC:11922 xref: UniGene:Hs.355307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055193 ! CD27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017295 name: CD2_human def: "T-cell surface antigen CD2 precursor gene" [UniProtKB:P06729] synonym: "SRBC" EXACT [UniProtKB:P06729] xref: EMBL:AL135798 xref: EMBL:BC033583 xref: EMBL:M14362 xref: EMBL:M16336 xref: EMBL:M16445 xref: EMBL:M19798 xref: EMBL:M19800 xref: EMBL:M19802 xref: EMBL:M19804 xref: EMBL:M19806 xref: EMBL:X07871 xref: EMBL:X07872 xref: EMBL:X07873 xref: EMBL:X07874 xref: HGNC:HGNC:1639 xref: UniGene:Hs.523500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023521 ! CD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017296 name: CD320_human def: "CD320 antigen precursor gene" [UniProtKB:Q9NPF0] synonym: "8D6A" EXACT [UniProtKB:Q9NPF0] synonym: "UNQ198/PRO224" EXACT [UniProtKB:Q9NPF0] xref: EMBL:AC010323 xref: EMBL:AF161254 xref: EMBL:AK222623 xref: EMBL:AK315656 xref: EMBL:AL136652 xref: EMBL:AL365455 xref: EMBL:AY358420 xref: EMBL:BC000668 xref: EMBL:BC007083 xref: EMBL:CH471139 xref: EMBL:CR457174 xref: HGNC:HGNC:16692 xref: UniGene:Hs.558499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058849 ! CD320_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017297 name: CD33_human def: "Myeloid cell surface antigen CD33 precursor gene" [UniProtKB:P20138] synonym: "SIGLEC3" EXACT [UniProtKB:P20138] xref: EMBL:AY040541 xref: EMBL:BC028152 xref: EMBL:M23197 xref: HGNC:HGNC:1659 xref: UniGene:Hs.83731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055113 ! CD33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017298 name: CD38_human def: "ADP-ribosyl cyclase 1 gene" [UniProtKB:P28907] xref: EMBL:BC007964 xref: EMBL:D84276 xref: EMBL:D84277 xref: EMBL:D84284 xref: EMBL:M34461 xref: HGNC:HGNC:1667 xref: UniGene:Hs.479214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055207 ! CD38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017299 name: CD3D_human def: "T-cell surface glycoprotein CD3 delta chain precursor gene" [UniProtKB:P04234] synonym: "T3D" EXACT [UniProtKB:P04234] xref: EMBL:AP001582 xref: EMBL:BC039035 xref: EMBL:BC070321 xref: EMBL:M12726 xref: EMBL:M12727 xref: EMBL:X01451 xref: EMBL:X03934 xref: HGNC:HGNC:1673 xref: UniGene:Hs.504048 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054064 ! A8MVP6_HUMAN relationship: codes_for CCO:B0054890 ! CD3D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017300 name: CD3E_human def: "T-cell surface glycoprotein CD3 epsilon chain precursor gene" [UniProtKB:P07766] synonym: "T3E" EXACT [UniProtKB:P07766] xref: EMBL:BC049847 xref: EMBL:L34846 xref: EMBL:M23317 xref: EMBL:M23318 xref: EMBL:M23319 xref: EMBL:M23320 xref: EMBL:M23321 xref: EMBL:M23322 xref: EMBL:M23323 xref: EMBL:X03884 xref: HGNC:HGNC:1674 xref: UniGene:Hs.3003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054916 ! CD3E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017301 name: CD3G_human def: "T-cell surface glycoprotein CD3 gamma chain precursor gene" [UniProtKB:P09693] synonym: "T3G" EXACT [UniProtKB:P09693] xref: EMBL:AP001582 xref: EMBL:BC113830 xref: EMBL:X04145 xref: EMBL:X06026 xref: EMBL:X06027 xref: EMBL:X06028 xref: EMBL:X06029 xref: EMBL:X06030 xref: EMBL:X06031 xref: HGNC:HGNC:1675 xref: UniGene:Hs.2259 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054041 ! A8MUH3_HUMAN relationship: codes_for CCO:B0054949 ! CD3G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017302 name: CD247_human def: "T-cell surface glycoprotein CD3 zeta chain precursor gene" [UniProtKB:P20963] synonym: "CD3Z" EXACT [UniProtKB:P20963] synonym: "T3Z" EXACT [UniProtKB:P20963] synonym: "TCRZ" EXACT [UniProtKB:P20963] xref: EMBL:AK313946 xref: EMBL:AL031733 xref: EMBL:AL359962 xref: EMBL:BC025703 xref: EMBL:CH471067 xref: EMBL:DQ072717 xref: EMBL:J04132 xref: HGNC:HGNC:1677 xref: UniGene:Hs.156445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054225 ! B1AK49_HUMAN relationship: codes_for CCO:B0055130 ! CD3Z_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017303 name: CD47_human def: "Leukocyte surface antigen CD47 precursor gene" [UniProtKB:Q08722] synonym: "MER6" EXACT [UniProtKB:Q08722] xref: EMBL:BC010016 xref: EMBL:BC012884 xref: EMBL:BC037306 xref: EMBL:BT006907 xref: EMBL:X69398 xref: EMBL:Z25521 xref: HGNC:HGNC:1682 xref: UniGene:Hs.446414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055793 ! CD47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017304 name: CD53_human def: "Leukocyte surface antigen CD53 gene" [UniProtKB:P19397] synonym: "MOX44" EXACT [UniProtKB:P19397] synonym: "TSPAN25" EXACT [UniProtKB:P19397] xref: EMBL:AL391064 xref: EMBL:BC040693 xref: EMBL:BT019643 xref: EMBL:M37033 xref: EMBL:M60871 xref: HGNC:HGNC:1686 xref: UniGene:Hs.443057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055108 ! CD53_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017305 name: CD5_human def: "T-cell surface glycoprotein CD5 precursor gene" [UniProtKB:P06127] synonym: "LEU1" EXACT [UniProtKB:P06127] xref: EMBL:AJ237927 xref: EMBL:AJ237928 xref: EMBL:AJ237929 xref: EMBL:AJ237930 xref: EMBL:AJ237931 xref: EMBL:AJ237932 xref: EMBL:BC027901 xref: EMBL:X04391 xref: EMBL:X89405 xref: HGNC:HGNC:1685 xref: UniGene:Hs.58685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054901 ! CD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017306 name: CD63_human def: "CD63 antigen gene" [UniProtKB:P08962] synonym: "MLA1" EXACT [UniProtKB:P08962] synonym: "TSPAN30" EXACT [UniProtKB:P08962] xref: EMBL:BC002349 xref: EMBL:BC013017 xref: EMBL:BT007073 xref: EMBL:M58485 xref: EMBL:M59907 xref: EMBL:S93788 xref: EMBL:X07982 xref: EMBL:X62654 xref: HGNC:HGNC:1692 xref: UniGene:Hs.445570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054939 ! CD63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017307 name: CD70_human def: "CD70 antigen gene" [UniProtKB:P32970] synonym: "CD27L" EXACT [UniProtKB:P32970] synonym: "CD27LG" EXACT [UniProtKB:P32970] synonym: "TNFSF7" EXACT [UniProtKB:P32970] xref: EMBL:BC000725 xref: EMBL:L08096 xref: EMBL:S69339 xref: HGNC:HGNC:11937 xref: UniGene:Hs.501497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055262 ! CD70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017308 name: CD79A_human def: "B-cell antigen receptor complex-associated protein alpha-chain precursor gene" [UniProtKB:P11912] synonym: "IGA" EXACT [UniProtKB:P11912] synonym: "MB1" EXACT [UniProtKB:P11912] xref: EMBL:AK223371 xref: EMBL:M74721 xref: EMBL:M80462 xref: EMBL:M86921 xref: EMBL:S46706 xref: EMBL:S75217 xref: EMBL:U05259 xref: EMBL:X13451 xref: EMBL:X83540 xref: HGNC:HGNC:1698 xref: UniGene:Hs.631567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054996 ! CD79A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017309 name: CD79B_human def: "B-cell antigen receptor complex-associated protein beta-chain precursor gene" [UniProtKB:P40259] synonym: "B29" EXACT [UniProtKB:P40259] synonym: "IGB" EXACT [UniProtKB:P40259] xref: EMBL:AK222954 xref: EMBL:AK223210 xref: EMBL:BC002975 xref: EMBL:BC032651 xref: EMBL:L27587 xref: EMBL:M80461 xref: EMBL:M89957 xref: EMBL:S52229 xref: EMBL:S79249 xref: EMBL:X83539 xref: HGNC:HGNC:1699 xref: UniGene:Hs.89575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055328 ! CD79B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017310 name: CD7_human def: "T-cell antigen CD7 precursor gene" [UniProtKB:P09564] xref: EMBL:BC009293 xref: EMBL:BC013297 xref: EMBL:BT006696 xref: EMBL:D00749 xref: EMBL:M37271 xref: EMBL:X06180 xref: HGNC:HGNC:1695 xref: UniGene:Hs.36972 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054946 ! CD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017311 name: CD80_human def: "T-lymphocyte activation antigen CD80 precursor gene" [UniProtKB:P33681] synonym: "CD28LG" EXACT [UniProtKB:P33681] synonym: "CD28LG1" EXACT [UniProtKB:P33681] synonym: "LAB7" EXACT [UniProtKB:P33681] xref: EMBL:BC042665 xref: EMBL:M27533 xref: EMBL:M83072 xref: EMBL:M83073 xref: EMBL:M83074 xref: EMBL:M83077 xref: HGNC:HGNC:1700 xref: UniGene:Hs.838 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055268 ! CD80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017312 name: CD83_human def: "CD83 antigen precursor gene" [UniProtKB:Q01151] xref: EMBL:BC030830 xref: EMBL:S53354 xref: EMBL:Z11697 xref: HGNC:HGNC:1703 xref: UniGene:Hs.654558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055687 ! CD83_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017313 name: CD86_human def: "T-lymphocyte activation antigen CD86 precursor gene" [UniProtKB:P42081] synonym: "CD28LG2" EXACT [UniProtKB:P42081] xref: EMBL:BC040261 xref: EMBL:CR541844 xref: EMBL:EF064748 xref: EMBL:L25259 xref: EMBL:U04343 xref: EMBL:U17717 xref: EMBL:U17718 xref: EMBL:U17719 xref: EMBL:U17721 xref: EMBL:U17722 xref: HGNC:HGNC:1705 xref: UniGene:Hs.171182 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055346 ! CD86_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017314 name: CD8A_human def: "T-cell surface glycoprotein CD8 alpha chain precursor gene" [UniProtKB:P01732] synonym: "MAL" EXACT [UniProtKB:P01732] xref: EMBL:M12824 xref: EMBL:M12828 xref: EMBL:M26313 xref: EMBL:M26314 xref: EMBL:M26315 xref: EMBL:M27161 xref: HGNC:HGNC:1706 xref: UniGene:Hs.85258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054856 ! CD8A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017315 name: CD8B_human def: "T-cell surface glycoprotein CD8 beta chain precursor gene" [UniProtKB:P10966] synonym: "CD8B1" EXACT [UniProtKB:P10966] xref: EMBL:M36712 xref: EMBL:S55730 xref: EMBL:S55731 xref: EMBL:S55733 xref: EMBL:S87068 xref: EMBL:S87070 xref: EMBL:S87073 xref: EMBL:S87078 xref: EMBL:S87081 xref: EMBL:S87083 xref: EMBL:S87087 xref: EMBL:S87090 xref: EMBL:X13444 xref: EMBL:X13445 xref: EMBL:X13446 xref: EMBL:X13452 xref: EMBL:Y00805 xref: HGNC:HGNC:1707 xref: UniGene:Hs.405667 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054983 ! CD8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017316 name: CD97_human def: "CD97 antigen precursor gene" [UniProtKB:P48960] xref: EMBL:AB065966 xref: EMBL:AC005327 xref: EMBL:AC008569 xref: EMBL:BC026690 xref: EMBL:U76764 xref: EMBL:X84700 xref: EMBL:X94630 xref: EMBL:X94631 xref: EMBL:X94632 xref: EMBL:X94633 xref: EMBL:X94634 xref: EMBL:X94635 xref: EMBL:X94636 xref: EMBL:X94637 xref: EMBL:X94638 xref: EMBL:X94639 xref: EMBL:X94640 xref: EMBL:X94641 xref: EMBL:X94642 xref: EMBL:X94643 xref: EMBL:X94644 xref: EMBL:X94645 xref: EMBL:X94646 xref: EMBL:X94647 xref: EMBL:Z99830 xref: EMBL:Z99831 xref: HGNC:HGNC:1711 xref: UniGene:Hs.466039 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054136 ! A8MZ46_HUMAN relationship: codes_for CCO:B0055413 ! CD97_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017317 name: CDCA7L_human def: "Cell division cycle-associated 7-like protein gene" [UniProtKB:Q96GN5] synonym: "HR1" EXACT [UniProtKB:Q96GN5] synonym: "JPO2" EXACT [UniProtKB:Q96GN5] synonym: "R1" EXACT [UniProtKB:Q96GN5] xref: EMBL:AK022955 xref: EMBL:AL359619 xref: EMBL:AY161168 xref: EMBL:AY161169 xref: EMBL:BC009352 xref: EMBL:BC014630 xref: EMBL:BC025242 xref: EMBL:BC032576 xref: EMBL:BC039823 xref: HGNC:HGNC:30777 xref: UniGene:Hs.520245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058219 ! CDA7L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017318 name: CDCA7_human def: "Cell division cycle-associated protein 7 gene" [UniProtKB:Q9BWT1] synonym: "JPO1" EXACT [UniProtKB:Q9BWT1] xref: EMBL:AC092573 xref: EMBL:AK027628 xref: EMBL:AK027642 xref: EMBL:AK075134 xref: EMBL:AK223524 xref: EMBL:AL833728 xref: EMBL:AL834186 xref: EMBL:AY029179 xref: EMBL:BC015124 xref: EMBL:BC027966 xref: EMBL:BG354580 xref: HGNC:HGNC:14628 xref: UniGene:Hs.470654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058536 ! CDCA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017319 name: CDGAP_human def: "Cdc42 GTPase-activating protein gene" [UniProtKB:Q2M1Z3] synonym: "KIAA1204" EXACT [UniProtKB:Q2M1Z3] xref: EMBL:AB033030 xref: EMBL:BC112163 xref: EMBL:BC112165 xref: UniGene:Hs.657263 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056207 ! CDGAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017320 name: CDKL2_human def: "Cyclin-dependent kinase-like 2 gene" [UniProtKB:Q92772] xref: EMBL:BC093646 xref: EMBL:BC093981 xref: EMBL:U35146 xref: HGNC:HGNC:1782 xref: UniGene:Hs.591698 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027165 ! CDKL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017321 name: CDS1_human def: "Phosphatidate cytidylyltransferase 1 gene" [UniProtKB:Q92903] synonym: "CDS" EXACT [UniProtKB:Q92903] xref: EMBL:BC074833 xref: EMBL:BC074881 xref: EMBL:U60808 xref: EMBL:U65887 xref: HGNC:HGNC:1800 xref: UniGene:Hs.654899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058110 ! CDS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017322 name: CDV3_human def: "Protein CDV3 homolog gene" [UniProtKB:Q9UKY7] synonym: "H41" EXACT [UniProtKB:Q9UKY7] xref: EMBL:AF103803 xref: EMBL:BC007338 xref: HGNC:HGNC:26928 xref: UniGene:Hs.518265 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059209 ! CDV3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017323 name: CDX4_human def: "Homeobox protein CDX-4 gene" [UniProtKB:O14627] xref: EMBL:AF003530 xref: EMBL:AF029877 xref: EMBL:AF029878 xref: EMBL:AF029879 xref: EMBL:AL450108 xref: HGNC:HGNC:1808 xref: UniGene:Hs.553488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054361 ! CDX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017324 name: CEBPA_human def: "CCAAT/enhancer-binding protein alpha gene" [UniProtKB:P49715] xref: EMBL:BC027902 xref: EMBL:EU048234 xref: EMBL:U34070 xref: EMBL:Y11525 xref: HGNC:HGNC:1833 xref: UniGene:Hs.699463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055431 ! CEBPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017325 name: CEBPD_human def: "CCAAT/enhancer-binding protein delta gene" [UniProtKB:P49716] xref: EMBL:BC105109 xref: EMBL:CH471068 xref: EMBL:M83667 xref: EMBL:S63168 xref: HGNC:HGNC:1835 xref: UniGene:Hs.440829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055432 ! CEBPD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017326 name: CEBPE_human def: "CCAAT/enhancer-binding protein epsilon gene" [UniProtKB:Q15744] xref: EMBL:BC035797 xref: EMBL:U48865 xref: EMBL:U48866 xref: EMBL:U80982 xref: HGNC:HGNC:1836 xref: UniGene:Hs.558308 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056103 ! CEBPE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017327 name: CECR2_human def: "Cat eye syndrome critical region protein 2 gene" [UniProtKB:Q9BXF3] synonym: "KIAA1740" EXACT [UniProtKB:Q9BXF3] xref: EMBL:AB051527 xref: EMBL:AC004019 xref: EMBL:AF336133 xref: EMBL:AF411609 xref: EMBL:AL832377 xref: EMBL:BX647449 xref: EMBL:CH471193 xref: HGNC:HGNC:1840 xref: UniGene:Hs.658723 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058552 ! CECR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017328 name: CELSR1_human def: "Cadherin EGF LAG seven-pass G-type receptor 1 precursor gene" [UniProtKB:Q9NYQ6] synonym: "CDHF9" EXACT [UniProtKB:Q9NYQ6] synonym: "FMI2" EXACT [UniProtKB:Q9NYQ6] xref: EMBL:AF231024 xref: EMBL:AL021392 xref: EMBL:AL031588 xref: EMBL:AL031597 xref: EMBL:BC000059 xref: HGNC:HGNC:1850 xref: UniGene:Hs.252387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054049 ! A8MUW4_HUMAN relationship: codes_for CCO:B0058968 ! CELR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017329 name: CENTA2_human def: "Centaurin-alpha-2 gene" [UniProtKB:Q9NPF8] xref: EMBL:AJ238994 xref: EMBL:AJ242782 xref: EMBL:AJ272195 xref: EMBL:BC033758 xref: EMBL:DQ288859 xref: HGNC:HGNC:16487 xref: UniGene:Hs.514063 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056233 ! Q2V6Q1_HUMAN relationship: codes_for CCO:B0058850 ! CENA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017330 name: CENTD3_human def: "Centaurin-delta-3 gene" [UniProtKB:Q8WWN8] synonym: "ARAP3" EXACT [UniProtKB:Q8WWN8] xref: EMBL:AJ310567 xref: HGNC:HGNC:24097 xref: UniGene:Hs.25277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024597 ! CEND3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017331 name: CENTG1_human def: "Centaurin-gamma-1 gene" [UniProtKB:Q99490] synonym: "AGAP2" EXACT [UniProtKB:Q99490] synonym: "KIAA0167" EXACT [UniProtKB:Q99490] xref: EMBL:AF384128 xref: EMBL:AF413077 xref: EMBL:AY128689 xref: EMBL:BC028020 xref: EMBL:D79989 xref: EMBL:U81031 xref: HGNC:HGNC:16921 xref: UniGene:Hs.302435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058417 ! CENG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017332 name: CENTG3_human def: "Centaurin-gamma-3 gene" [UniProtKB:Q96P47] synonym: "AGAP3" EXACT [UniProtKB:Q96P47] xref: EMBL:AB209781 xref: EMBL:AF359283 xref: EMBL:AF413079 xref: EMBL:BC048300 xref: HGNC:HGNC:16923 xref: UniGene:Hs.647075 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057296 ! Q86XV5_HUMAN relationship: codes_for CCO:B0058317 ! CENG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017333 name: MLF1IP_human def: "Centromere protein U gene" [UniProtKB:Q71F23] synonym: "CENPU" EXACT [UniProtKB:Q71F23] synonym: "ICEN24" EXACT [UniProtKB:Q71F23] synonym: "KLIP1" EXACT [UniProtKB:Q71F23] synonym: "PBIP1" EXACT [UniProtKB:Q71F23] xref: EMBL:AF469667 xref: EMBL:AF516710 xref: EMBL:AK027121 xref: EMBL:BC031520 xref: EMBL:BC107744 xref: EMBL:CR457376 xref: HGNC:HGNC:21348 xref: UniGene:Hs.481307 xref: UniGene:Hs.575032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057096 ! CENPU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017334 name: CEP57_human def: "Centrosomal protein of 57 kDa gene" [UniProtKB:Q86XR8] synonym: "KIAA0092" EXACT [UniProtKB:Q86XR8] synonym: "TSP57" EXACT [UniProtKB:Q86XR8] xref: EMBL:AY225092 xref: EMBL:BC001233 xref: EMBL:BC039711 xref: EMBL:D42054 xref: HGNC:HGNC:30794 xref: UniGene:Hs.101014 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057294 ! CEP57_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017335 name: CER1_human def: "Cerberus precursor gene" [UniProtKB:O95813] synonym: "DAND4" EXACT [UniProtKB:O95813] xref: EMBL:AF090189 xref: EMBL:AF400435 xref: EMBL:AL390732 xref: EMBL:BC069371 xref: EMBL:BC069405 xref: EMBL:BC069491 xref: EMBL:BC069503 xref: HGNC:HGNC:1862 xref: UniGene:Hs.248204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054795 ! CER1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017336 name: CERK_human def: "Ceramide kinase gene" [UniProtKB:Q8TCT0] synonym: "KIAA1646" EXACT [UniProtKB:Q8TCT0] xref: EMBL:AB051433 xref: EMBL:AB079066 xref: EMBL:AJ457828 xref: EMBL:AL096766 xref: EMBL:AL118516 xref: EMBL:BC126940 xref: EMBL:CR456404 xref: HGNC:HGNC:19256 xref: UniGene:Hs.200668 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057916 ! CERK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017337 name: CERKL_human def: "Ceramide kinase-like protein gene" [UniProtKB:Q49MI3] xref: EMBL:AJ640141 xref: EMBL:AJ697855 xref: EMBL:AJ697856 xref: EMBL:AJ697858 xref: EMBL:AK129976 xref: EMBL:AY357073 xref: EMBL:AY690329 xref: EMBL:AY690330 xref: EMBL:AY690331 xref: EMBL:AY690332 xref: EMBL:AY690333 xref: HGNC:HGNC:21699 xref: UniGene:Hs.440955 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056307 ! CERKL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017338 name: C6orf170_human def: "Transmembrane protein C6orf170 gene" [UniProtKB:Q96NH3] synonym: "C6orf171" EXACT [UniProtKB:Q96NH3] xref: EMBL:AK055461 xref: EMBL:AK091554 xref: EMBL:AK125385 xref: EMBL:AK131446 xref: EMBL:AL035593 xref: EMBL:AL139098 xref: EMBL:AL365508 xref: EMBL:AL589910 xref: EMBL:AL590225 xref: HGNC:HGNC:21485 xref: UniGene:Hs.121396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058305 ! CF170_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017339 name: CFDP1_human def: "Craniofacial development protein 1 gene" [UniProtKB:Q9UEE9] synonym: "BCNT" EXACT [UniProtKB:Q9UEE9] xref: EMBL:AB004907 xref: EMBL:AB009269 xref: EMBL:AB009270 xref: EMBL:AB009285 xref: EMBL:BC000991 xref: EMBL:BT009819 xref: EMBL:CR542111 xref: EMBL:D85939 xref: EMBL:D86549 xref: HGNC:HGNC:1873 xref: UniGene:Hs.461361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059107 ! CFDP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017340 name: CFLAR_human def: "CASP8 and FADD-like apoptosis regulator precursor gene" [UniProtKB:O15519] synonym: "CASH" EXACT [UniProtKB:O15519] synonym: "CASP8AP1" EXACT [UniProtKB:O15519] synonym: "CLARP" EXACT [UniProtKB:O15519] synonym: "MRIT" EXACT [UniProtKB:O15519] xref: EMBL:AB038972 xref: EMBL:AF005774 xref: EMBL:AF005775 xref: EMBL:AF009616 xref: EMBL:AF009617 xref: EMBL:AF009618 xref: EMBL:AF009619 xref: EMBL:AF010127 xref: EMBL:AF015450 xref: EMBL:AF015451 xref: EMBL:AF015452 xref: EMBL:AF041458 xref: EMBL:AF041459 xref: EMBL:AF041460 xref: EMBL:AF041461 xref: EMBL:AF041462 xref: EMBL:BC001602 xref: EMBL:BT006751 xref: EMBL:U85059 xref: EMBL:U97074 xref: EMBL:U97075 xref: EMBL:Y14039 xref: EMBL:Y14040 xref: HGNC:HGNC:1876 xref: UniGene:Hs.390736 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054442 ! CFLAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017341 name: C7orf64_human def: "Uncharacterized protein C7orf64 gene" [UniProtKB:Q5RL73] xref: EMBL:AK054777 xref: EMBL:BC033561 xref: EMBL:BC044570 xref: EMBL:BC104865 xref: EMBL:BC104867 xref: EMBL:CH236949 xref: EMBL:CH471091 xref: EMBL:CR933641 xref: HGNC:HGNC:21785 xref: UniGene:Hs.21590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061993 ! CG064_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017342 name: CSGALNACT1_human def: "Chondroitin sulfate N-acetylgalactosaminyltransferase 1 gene" [UniProtKB:Q8TDX6] synonym: "CHGN" EXACT [UniProtKB:Q8TDX6] synonym: "GALNACT1" EXACT [UniProtKB:Q8TDX6] synonym: "UNQ656/PRO1287" EXACT [UniProtKB:Q8TDX6] xref: EMBL:AB071403 xref: EMBL:AB081516 xref: EMBL:AK002126 xref: EMBL:AL157483 xref: EMBL:AY358441 xref: EMBL:BC060772 xref: HGNC:HGNC:24290 xref: UniGene:Hs.655166 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057945 ! CGAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017343 name: CGGBP1_human def: "CGG triplet repeat-binding protein 1 gene" [UniProtKB:Q9UFW8] synonym: "CGGBP" EXACT [UniProtKB:Q9UFW8] xref: EMBL:AF094481 xref: EMBL:AJ000258 xref: EMBL:AL117392 xref: EMBL:AM393707 xref: EMBL:BC052980 xref: EMBL:CR456854 xref: HGNC:HGNC:1888 xref: UniGene:Hs.444818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059117 ! CGBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017344 name: CGB_human def: "Choriogonadotropin subunit beta precursor gene" [UniProtKB:P01233] synonym: "CGB3" EXACT [UniProtKB:P01233] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054841 ! CGHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017345 name: CGB5_human def: "Choriogonadotropin subunit beta precursor gene" [UniProtKB:P01233] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054841 ! CGHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017346 name: CGB7_human def: "Choriogonadotropin subunit beta precursor gene" [UniProtKB:P01233] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054841 ! CGHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017347 name: CGB8_human def: "Choriogonadotropin subunit beta precursor gene" [UniProtKB:P01233] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054841 ! CGHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017348 name: CHAD_human def: "Chondroadherin precursor gene" [UniProtKB:O15335] synonym: "SLRR4A" EXACT [UniProtKB:O15335] xref: EMBL:AF371328 xref: EMBL:BC036360 xref: EMBL:BC073974 xref: EMBL:U96767 xref: EMBL:U96768 xref: EMBL:U96769 xref: HGNC:HGNC:1909 xref: UniGene:Hs.97220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054430 ! CHAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017349 name: CHD4_human def: "Chromodomain-helicase-DNA-binding protein 4 gene" [UniProtKB:Q14839] xref: EMBL:BC038596 xref: EMBL:X86691 xref: HGNC:HGNC:1919 xref: UniGene:Hs.162233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056018 ! CHD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017350 name: CHD5_human def: "Chromodomain-helicase-DNA-binding protein 5 gene" [UniProtKB:Q8TDI0] synonym: "KIAA0444" EXACT [UniProtKB:Q8TDI0] xref: EMBL:AB007913 xref: EMBL:AF425231 xref: EMBL:AL031847 xref: EMBL:AL035406 xref: EMBL:AL117491 xref: HGNC:HGNC:16816 xref: UniGene:Hs.522898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053907 ! A6NMM4_HUMAN relationship: codes_for CCO:B0056622 ! Q5TG85_HUMAN relationship: codes_for CCO:B0057928 ! CHD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017351 name: CHD6_human def: "Chromodomain-helicase-DNA-binding protein 6 gene" [UniProtKB:Q8TD26] synonym: "CHD5" EXACT [UniProtKB:Q8TD26] synonym: "KIAA1335" EXACT [UniProtKB:Q8TD26] synonym: "RIGB" EXACT [UniProtKB:Q8TD26] xref: EMBL:AB037756 xref: EMBL:AF525085 xref: EMBL:AK026022 xref: EMBL:AL031667 xref: EMBL:AL031669 xref: EMBL:AL121674 xref: EMBL:AY034072 xref: EMBL:BC021907 xref: EMBL:BC039860 xref: EMBL:BC040016 xref: HGNC:HGNC:19057 xref: UniGene:Hs.371979 xref: UniGene:Hs.697565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057921 ! CHD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017352 name: CHD7_human def: "Chromodomain-helicase-DNA-binding protein 7 gene" [UniProtKB:Q9P2D1] synonym: "KIAA1416" EXACT [UniProtKB:Q9P2D1] xref: EMBL:AB037837 xref: EMBL:AC023102 xref: EMBL:AC113143 xref: EMBL:AK000364 xref: EMBL:AK000368 xref: EMBL:BC014681 xref: EMBL:BC051264 xref: EMBL:BC053890 xref: EMBL:BC068000 xref: EMBL:BC080627 xref: EMBL:BC110818 xref: HGNC:HGNC:20626 xref: UniGene:Hs.20395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059056 ! CHD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017353 name: CHD9_human def: "Chromodomain-helicase-DNA-binding protein 9 gene" [UniProtKB:Q3L8U1] synonym: "AD-013" EXACT [UniProtKB:Q3L8U1] synonym: "KIAA0308" EXACT [UniProtKB:Q3L8U1] synonym: "KISH2" EXACT [UniProtKB:Q3L8U1] synonym: "PRIC320" EXACT [UniProtKB:Q3L8U1] synonym: "x0008" EXACT [UniProtKB:Q3L8U1] xref: EMBL:AB002306 xref: EMBL:AC007906 xref: EMBL:AC079416 xref: EMBL:AF150735 xref: EMBL:AK022582 xref: EMBL:AY243500 xref: EMBL:AY647157 xref: EMBL:DQ333316 xref: HGNC:HGNC:25701 xref: UniGene:Hs.59159 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056261 ! CHD9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017354 name: CHN1_human def: "N-chimaerin gene" [UniProtKB:P15882] synonym: "ARHGAP2" EXACT [UniProtKB:P15882] synonym: "CHN" EXACT [UniProtKB:P15882] xref: EMBL:AC007435 xref: EMBL:AC018890 xref: EMBL:AC020596 xref: EMBL:BC011393 xref: EMBL:S75654 xref: EMBL:X51408 xref: EMBL:Z22641 xref: HGNC:HGNC:1943 xref: UniGene:Hs.654534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055044 ! CHIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017355 name: CHN2_human def: "Beta-chimaerin gene" [UniProtKB:P52757] synonym: "ARHGAP3" EXACT [UniProtKB:P52757] synonym: "BCH" EXACT [UniProtKB:P52757] xref: EMBL:AC004417 xref: EMBL:AC007255 xref: EMBL:BC112155 xref: EMBL:L29126 xref: EMBL:U07223 xref: EMBL:U28926 xref: HGNC:HGNC:1944 xref: UniGene:Hs.654611 xref: UniGene:Hs.654753 xref: UniGene:Hs.663145 xref: UniGene:Hs.705872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055500 ! CHIO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017356 name: CHMP5_human def: "Charged multivesicular body protein 5 gene" [UniProtKB:Q9NZZ3] synonym: "C9orf83" EXACT [UniProtKB:Q9NZZ3] synonym: "CGI-34" EXACT [UniProtKB:Q9NZZ3] synonym: "HSPC177" EXACT [UniProtKB:Q9NZZ3] synonym: "PNAS-114" EXACT [UniProtKB:Q9NZZ3] synonym: "PNAS-2" EXACT [UniProtKB:Q9NZZ3] synonym: "SNF7DC2" EXACT [UniProtKB:Q9NZZ3] xref: EMBL:AF132968 xref: EMBL:AF161525 xref: EMBL:AF229832 xref: EMBL:AF275810 xref: EMBL:AL356472 xref: EMBL:BC006974 xref: EMBL:BC007457 xref: EMBL:BC016698 xref: EMBL:BC020796 xref: EMBL:BC021168 xref: HGNC:HGNC:26942 xref: UniGene:Hs.635313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059023 ! CHMP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017357 name: CHP_human def: "Calcium-binding protein p22 gene" [UniProtKB:Q99653] xref: EMBL:BC031293 xref: EMBL:BC051815 xref: EMBL:CH471125 xref: EMBL:CR536539 xref: EMBL:CR542085 xref: EMBL:U61538 xref: UniGene:Hs.406234 xref: UniGene:Hs.706184 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058435 ! CHP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017358 name: CHPT1_human def: "Cholinephosphotransferase 1 gene" [UniProtKB:Q8WUD6] synonym: "CPT1" EXACT [UniProtKB:Q8WUD6] synonym: "MSTP022" EXACT [UniProtKB:Q8WUD6] xref: EMBL:AF047431 xref: EMBL:AF111803 xref: EMBL:AF195623 xref: EMBL:AF195624 xref: EMBL:AY166717 xref: EMBL:AY166718 xref: EMBL:AY280609 xref: EMBL:AY280610 xref: EMBL:AY294627 xref: EMBL:BC020819 xref: EMBL:BC050429 xref: HGNC:HGNC:17852 xref: UniGene:Hs.293077 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057978 ! CHPT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017359 name: CHURC1_human def: "Protein Churchill gene" [UniProtKB:Q8WUH1] synonym: "C14orf52" EXACT [UniProtKB:Q8WUH1] synonym: "CHCH" EXACT [UniProtKB:Q8WUH1] synonym: "My015" EXACT [UniProtKB:Q8WUH1] xref: EMBL:AF060510 xref: EMBL:BC020550 xref: HGNC:HGNC:20099 xref: UniGene:Hs.325531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057980 ! CHUR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017360 name: C9orf100_human def: "Vav-like protein C9orf100 gene" [UniProtKB:Q8N4T4] xref: EMBL:AK027548 xref: EMBL:AL357874 xref: EMBL:AY390225 xref: EMBL:AY390226 xref: EMBL:BC033666 xref: EMBL:BC038673 xref: HGNC:HGNC:25909 xref: UniGene:Hs.705802 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057467 ! CI100_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017361 name: CIAO1_human def: "Protein CIAO1 gene" [UniProtKB:O76071] synonym: "WDR39" EXACT [UniProtKB:O76071] xref: EMBL:AC004020 xref: EMBL:AK223257 xref: EMBL:BC001395 xref: EMBL:BC032812 xref: EMBL:CR456802 xref: EMBL:EF011618 xref: EMBL:U63810 xref: HGNC:HGNC:14280 xref: UniGene:Hs.12109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054691 ! CIAO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017362 name: CIDEA_human def: "Cell death activator CIDE-A gene" [UniProtKB:O60543] xref: EMBL:AF041378 xref: HGNC:HGNC:1976 xref: UniGene:Hs.249129 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054566 ! CIDEA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017363 name: CIDEB_human def: "Cell death activator CIDE-B gene" [UniProtKB:Q9UHD4] xref: EMBL:AF190901 xref: EMBL:AF218586 xref: EMBL:AK000387 xref: EMBL:BC035970 xref: HGNC:HGNC:1977 xref: UniGene:Hs.642693 xref: UniGene:Hs.657595 xref: UniGene:Hs.696081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059137 ! CIDEB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017364 name: CIDEC_human def: "Cell death activator CIDE-3 gene" [UniProtKB:Q96AQ7] synonym: "FSP27" EXACT [UniProtKB:Q96AQ7] xref: EMBL:AF303893 xref: EMBL:AK024524 xref: EMBL:AK024530 xref: EMBL:AY364638 xref: EMBL:AY364640 xref: EMBL:BC016851 xref: HGNC:HGNC:24229 xref: UniGene:Hs.567562 xref: UniGene:Hs.635072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058155 ! CIDEC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017365 name: TRAF3IP2_human def: "Adapter protein CIKS gene" [UniProtKB:O43734] synonym: "C6orf4" EXACT [UniProtKB:O43734] synonym: "C6orf5" EXACT [UniProtKB:O43734] synonym: "C6orf6" EXACT [UniProtKB:O43734] xref: EMBL:AF136405 xref: EMBL:AF136406 xref: EMBL:AF136407 xref: EMBL:AF272151 xref: EMBL:AF274303 xref: EMBL:AK025351 xref: EMBL:AK026602 xref: EMBL:AL008730 xref: EMBL:AL050289 xref: EMBL:BC002823 xref: EMBL:Z97989 xref: HGNC:HGNC:1343 xref: UniGene:Hs.654708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054515 ! CIKS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017366 name: CILP_human def: "Cartilage intermediate layer protein 1 precursor gene" [UniProtKB:O75339] synonym: "UNQ602/PRO1188" EXACT [UniProtKB:O75339] xref: EMBL:AB022430 xref: EMBL:AF035408 xref: EMBL:AF035448 xref: EMBL:AF035449 xref: EMBL:AF035451 xref: EMBL:AF035453 xref: EMBL:AF035455 xref: EMBL:AY358904 xref: EMBL:BC035776 xref: HGNC:HGNC:1980 xref: UniGene:Hs.442180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054617 ! CILP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017367 name: TRIP10_human def: "Cdc42-interacting protein 4 gene" [UniProtKB:Q15642] synonym: "CIP4" EXACT [UniProtKB:Q15642] synonym: "STOT" EXACT [UniProtKB:Q15642] synonym: "STP" EXACT [UniProtKB:Q15642] xref: EMBL:AB072596 xref: EMBL:AF380114 xref: EMBL:AF502289 xref: EMBL:AJ000414 xref: EMBL:AK223109 xref: EMBL:AY081141 xref: EMBL:BC013002 xref: EMBL:BT006698 xref: EMBL:BT020167 xref: EMBL:BT020171 xref: EMBL:CR536513 xref: EMBL:L40379 xref: HGNC:HGNC:12304 xref: UniGene:Hs.515094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056090 ! CIP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017368 name: CIR_human def: "CBF1-interacting corepressor gene" [UniProtKB:Q86X95] xref: EMBL:AC018470 xref: EMBL:AF098297 xref: EMBL:BC015040 xref: EMBL:BC021175 xref: EMBL:BC038987 xref: EMBL:BC046098 xref: EMBL:U03644 xref: UniGene:Hs.632531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057286 ! CIR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017369 name: CISH_human def: "Cytokine-inducible SH2-containing protein gene" [UniProtKB:Q9NSE2] synonym: "G18" EXACT [UniProtKB:Q9NSE2] xref: EMBL:AF035947 xref: EMBL:AF132297 xref: EMBL:BC031590 xref: EMBL:BC064354 xref: EMBL:D83532 xref: HGNC:HGNC:1984 xref: UniGene:Hs.655334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058919 ! CISH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017370 name: C11orf9_human def: "Uncharacterized protein C11orf9 gene" [UniProtKB:Q9Y2G1] synonym: "KIAA0954" EXACT [UniProtKB:Q9Y2G1] xref: EMBL:AB023171 xref: EMBL:AF086762 xref: EMBL:CH471076 xref: HGNC:HGNC:1181 xref: UniGene:Hs.473109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059302 ! CK009_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017371 name: CKLF_human def: "Chemokine-like factor gene" [UniProtKB:Q9UBR5] synonym: "CKLF1" EXACT [UniProtKB:Q9UBR5] synonym: "HSPC224" EXACT [UniProtKB:Q9UBR5] synonym: "UNQ410/PRO772" EXACT [UniProtKB:Q9UBR5] xref: EMBL:AF057306 xref: EMBL:AF096895 xref: EMBL:AF135380 xref: EMBL:AF135381 xref: EMBL:AF145216 xref: EMBL:AF151058 xref: EMBL:AY358999 xref: EMBL:AY665769 xref: EMBL:BC004380 xref: HGNC:HGNC:13253 xref: UniGene:Hs.15159 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059082 ! CKLF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017372 name: CCL3L1_human def: "C-C motif chemokine 3-like 1 precursor gene" [UniProtKB:P16619] synonym: "D17S1718" EXACT [UniProtKB:P16619] synonym: "G0S19-2" EXACT [UniProtKB:P16619] synonym: "SCYA3L1" EXACT [UniProtKB:P16619] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055058 ! CL3L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017373 name: CCL3L3_human def: "C-C motif chemokine 3-like 1 precursor gene" [UniProtKB:P16619] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055058 ! CL3L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017374 name: CLEC11A_human def: "C-type lectin domain family 11 member A precursor gene" [UniProtKB:Q9Y240] synonym: "CLECSF3" EXACT [UniProtKB:Q9Y240] synonym: "LSLCL" EXACT [UniProtKB:Q9Y240] synonym: "SCGF" EXACT [UniProtKB:Q9Y240] xref: EMBL:AB009244 xref: EMBL:AF020044 xref: EMBL:AF087658 xref: EMBL:BC005810 xref: HGNC:HGNC:10576 xref: UniGene:Hs.512680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059291 ! CLC11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017375 name: CLEC1A_human def: "C-type lectin domain family 1 member A gene" [UniProtKB:Q8NC01] synonym: "CLEC1" EXACT [UniProtKB:Q8NC01] synonym: "UNQ569/PRO1131" EXACT [UniProtKB:Q8NC01] xref: EMBL:AF200949 xref: EMBL:AK075114 xref: EMBL:AY358587 xref: EMBL:BC039072 xref: EMBL:BC067746 xref: HGNC:HGNC:24355 xref: UniGene:Hs.29549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057560 ! CLC1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017376 name: CLEC1B_human def: "C-type lectin domain family 1 member B gene" [UniProtKB:Q9P126] synonym: "CLEC2" EXACT [UniProtKB:Q9P126] synonym: "UNQ721/PRO1384" EXACT [UniProtKB:Q9P126] xref: EMBL:AC091814 xref: EMBL:AF124841 xref: EMBL:AY358599 xref: EMBL:BC029554 xref: HGNC:HGNC:24356 xref: UniGene:Hs.409794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059037 ! CLC1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017377 name: CLEC2D_human def: "C-type lectin domain family 2 member D gene" [UniProtKB:Q9UHP7] synonym: "CLAX" EXACT [UniProtKB:Q9UHP7] synonym: "LLT1" EXACT [UniProtKB:Q9UHP7] synonym: "OCIL" EXACT [UniProtKB:Q9UHP7] xref: EMBL:AF133299 xref: EMBL:AF285087 xref: EMBL:AF285088 xref: EMBL:AF285089 xref: EMBL:AY144606 xref: EMBL:BC019883 xref: EMBL:CH471094 xref: HGNC:HGNC:14351 xref: UniGene:Hs.268326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059146 ! CLC2D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017378 name: CLEC4A_human def: "C-type lectin domain family 4 member A gene" [UniProtKB:Q9UMR7] synonym: "CLECSF6" EXACT [UniProtKB:Q9UMR7] synonym: "DCIR" EXACT [UniProtKB:Q9UMR7] synonym: "HDCGC13P" EXACT [UniProtKB:Q9UMR7] synonym: "LLIR" EXACT [UniProtKB:Q9UMR7] xref: EMBL:AF067800 xref: EMBL:AF109146 xref: EMBL:AF200738 xref: EMBL:AF328684 xref: EMBL:AJ133532 xref: EMBL:BC074822 xref: EMBL:BC074874 xref: EMBL:BC117439 xref: EMBL:BC117441 xref: HGNC:HGNC:13257 xref: UniGene:Hs.504657 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059241 ! CLC4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017379 name: CLEC4M_human def: "C-type lectin domain family 4 member M gene" [UniProtKB:Q9H2X3] synonym: "CD209L" EXACT [UniProtKB:Q9H2X3] synonym: "CD209L1" EXACT [UniProtKB:Q9H2X3] synonym: "CD299" EXACT [UniProtKB:Q9H2X3] xref: EMBL:AB015629 xref: EMBL:AC008812 xref: EMBL:AF209480 xref: EMBL:AF209481 xref: EMBL:AF245219 xref: EMBL:AF290887 xref: EMBL:AK023750 xref: EMBL:AY042234 xref: EMBL:AY042235 xref: EMBL:AY042236 xref: EMBL:AY042237 xref: EMBL:AY042238 xref: EMBL:AY042239 xref: EMBL:AY042240 xref: EMBL:AY343913 xref: EMBL:BC038851 xref: HGNC:HGNC:13523 xref: UniGene:Hs.421437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058691 ! CLC4M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017380 name: CLEC5A_human def: "C-type lectin domain family 5 member A gene" [UniProtKB:Q9NY25] synonym: "CLECSF5" EXACT [UniProtKB:Q9NY25] synonym: "MDL1" EXACT [UniProtKB:Q9NY25] xref: EMBL:AC073647 xref: EMBL:AF139768 xref: EMBL:AJ271684 xref: EMBL:BC093714 xref: EMBL:BC112099 xref: EMBL:BC113098 xref: HGNC:HGNC:2054 xref: UniGene:Hs.446235 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058957 ! CLC5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017381 name: CLEC7A_human def: "C-type lectin domain family 7 member A gene" [UniProtKB:Q9BXN2] synonym: "BGR" EXACT [UniProtKB:Q9BXN2] synonym: "CLECSF12" EXACT [UniProtKB:Q9BXN2] synonym: "DECTIN1" EXACT [UniProtKB:Q9BXN2] synonym: "UNQ539/PRO1082" EXACT [UniProtKB:Q9BXN2] xref: EMBL:AF313468 xref: EMBL:AF313469 xref: EMBL:AF400595 xref: EMBL:AF400596 xref: EMBL:AF400597 xref: EMBL:AF400598 xref: EMBL:AF400599 xref: EMBL:AF400600 xref: EMBL:AF400601 xref: EMBL:AJ312372 xref: EMBL:AJ312373 xref: EMBL:AY009090 xref: EMBL:AY026769 xref: EMBL:AY026770 xref: EMBL:AY026771 xref: EMBL:AY359002 xref: EMBL:BC071746 xref: HGNC:HGNC:14558 xref: UniGene:Hs.143929 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058561 ! CLC7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017382 name: CLCF1_human def: "Cardiotrophin-like cytokine factor 1 precursor gene" [UniProtKB:Q9UBD9] synonym: "BSF3" EXACT [UniProtKB:Q9UBD9] synonym: "CLC" EXACT [UniProtKB:Q9UBD9] synonym: "NNT1" EXACT [UniProtKB:Q9UBD9] xref: EMBL:AF172854 xref: EMBL:AF176911 xref: EMBL:AF176912 xref: EMBL:AY049779 xref: EMBL:BC012939 xref: EMBL:BC066229 xref: EMBL:BC066230 xref: EMBL:BC066231 xref: HGNC:HGNC:17412 xref: UniGene:Hs.502977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059069 ! CLCF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017383 name: CLCN6_human def: "Chloride channel protein 6 gene" [UniProtKB:P51797] synonym: "KIAA0046" EXACT [UniProtKB:P51797] xref: EMBL:AF009247 xref: EMBL:AF009248 xref: EMBL:AF009249 xref: EMBL:AF009250 xref: EMBL:AF009251 xref: EMBL:AF009252 xref: EMBL:AF009253 xref: EMBL:AF009254 xref: EMBL:AF009255 xref: EMBL:AF009256 xref: EMBL:AF009257 xref: EMBL:AL021155 xref: EMBL:AL953897 xref: EMBL:BC117420 xref: EMBL:BC117424 xref: EMBL:D28475 xref: EMBL:X83378 xref: EMBL:X96391 xref: EMBL:X99472 xref: EMBL:X99473 xref: EMBL:X99474 xref: EMBL:X99475 xref: HGNC:HGNC:2024 xref: UniGene:Hs.193043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055479 ! CLCN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017384 name: CLIC1_human def: "Chloride intracellular channel protein 1 gene" [UniProtKB:O00299] synonym: "NCC27" EXACT [UniProtKB:O00299] xref: EMBL:AF034607 xref: EMBL:AF109197 xref: EMBL:AF129756 xref: EMBL:AJ012008 xref: EMBL:AL662899 xref: EMBL:BA000025 xref: EMBL:BC064527 xref: EMBL:BC095469 xref: EMBL:CR542071 xref: EMBL:U93205 xref: EMBL:X87689 xref: HGNC:HGNC:2062 xref: UniGene:Hs.414565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054309 ! CLIC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017385 name: CLIC2_human def: "Chloride intracellular channel protein 2 gene" [UniProtKB:O15247] xref: EMBL:AJ000217 xref: EMBL:AJ000218 xref: EMBL:AJ000219 xref: EMBL:AL356738 xref: EMBL:BC022305 xref: EMBL:Y12696 xref: HGNC:HGNC:2063 xref: UniGene:Hs.655445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054419 ! CLIC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017386 name: CLIC3_human def: "Chloride intracellular channel protein 3 gene" [UniProtKB:O95833] xref: EMBL:AF102166 xref: EMBL:AL807752 xref: EMBL:BC007012 xref: EMBL:CH471090 xref: HGNC:HGNC:2064 xref: UniGene:Hs.64746 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054798 ! CLIC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017387 name: CLIC4_human def: "Chloride intracellular channel protein 4 gene" [UniProtKB:Q9Y696] xref: EMBL:AF097330 xref: EMBL:AF109196 xref: EMBL:AL117424 xref: EMBL:BC012444 xref: HGNC:HGNC:13518 xref: UniGene:Hs.440544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059402 ! CLIC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017388 name: CLN3_human def: "Battenin gene" [UniProtKB:Q13286] synonym: "BTS" EXACT [UniProtKB:Q13286] xref: EMBL:AC002425 xref: EMBL:AC002544 xref: EMBL:AF077956 xref: EMBL:AF077957 xref: EMBL:AF077958 xref: EMBL:AF077959 xref: EMBL:AF077960 xref: EMBL:AF077961 xref: EMBL:AF077962 xref: EMBL:AF077963 xref: EMBL:AF077965 xref: EMBL:AF077966 xref: EMBL:AF077971 xref: EMBL:AF077972 xref: EMBL:AF078169 xref: EMBL:BC002394 xref: EMBL:BC004433 xref: EMBL:U32680 xref: EMBL:X99832 xref: HGNC:HGNC:2074 xref: UniGene:Hs.628393 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055893 ! CLN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017389 name: CLN6_human def: "Ceroid-lipofuscinosis neuronal protein 6 gene" [UniProtKB:Q9NWW5] xref: EMBL:AK000568 xref: EMBL:AK027604 xref: EMBL:BC010849 xref: EMBL:BC013130 xref: EMBL:CR457244 xref: HGNC:HGNC:2077 xref: UniGene:Hs.584921 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058942 ! CLN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017390 name: CLN8_human def: "Protein CLN8 gene" [UniProtKB:Q9UBY8] synonym: "C8orf61" EXACT [UniProtKB:Q9UBY8] xref: EMBL:AF123757 xref: EMBL:AF123758 xref: EMBL:AF123759 xref: EMBL:AF123760 xref: EMBL:AF123761 xref: EMBL:BC007725 xref: EMBL:BT007049 xref: HGNC:HGNC:2079 xref: UniGene:Hs.127675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059091 ! CLN8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017391 name: CYSLTR1_human def: "Cysteinyl leukotriene receptor 1 gene" [UniProtKB:Q9Y271] synonym: "CYSLT1" EXACT [UniProtKB:Q9Y271] xref: EMBL:AF119711 xref: EMBL:AF133266 xref: EMBL:AL445202 xref: EMBL:AY242130 xref: EMBL:BC035750 xref: HGNC:HGNC:17451 xref: UniGene:Hs.201300 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018486 ! CLTR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017392 name: CYSLTR2_human def: "Cysteinyl leukotriene receptor 2 gene" [UniProtKB:Q9NS75] synonym: "CYSLT2" EXACT [UniProtKB:Q9NS75] synonym: "CYSLT2R" EXACT [UniProtKB:Q9NS75] synonym: "PSEC0146" EXACT [UniProtKB:Q9NS75] xref: EMBL:AB038269 xref: EMBL:AB041644 xref: EMBL:AB083603 xref: EMBL:AF254664 xref: EMBL:AF279611 xref: EMBL:AL137118 xref: EMBL:AY389504 xref: EMBL:BC069160 xref: HGNC:HGNC:18274 xref: UniGene:Hs.253706 xref: UniGene:Hs.614318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018485 ! CLTR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017393 name: CLU_human def: "Clusterin precursor gene" [UniProtKB:P10909] synonym: "APOJ" EXACT [UniProtKB:P10909] synonym: "CLI" EXACT [UniProtKB:P10909] synonym: "KUB1" EXACT [UniProtKB:P10909] xref: EMBL:AF311103 xref: EMBL:AY341244 xref: EMBL:BC010514 xref: EMBL:BC019588 xref: EMBL:BX648414 xref: EMBL:J02908 xref: EMBL:L00974 xref: EMBL:M25915 xref: EMBL:M63376 xref: EMBL:M63377 xref: EMBL:M63378 xref: EMBL:M63379 xref: EMBL:M64722 xref: EMBL:M74816 xref: EMBL:X14723 xref: HGNC:HGNC:2095 xref: UniGene:Hs.436657 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054980 ! CLUS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017394 name: CMKLR1_human def: "Chemokine receptor-like 1 gene" [UniProtKB:Q99788] synonym: "CHEMR23" EXACT [UniProtKB:Q99788] synonym: "DEZ" EXACT [UniProtKB:Q99788] xref: EMBL:AB065871 xref: EMBL:AY497547 xref: EMBL:BC106927 xref: EMBL:BC106928 xref: EMBL:L12406 xref: EMBL:U79526 xref: EMBL:U79527 xref: EMBL:Y14838 xref: HGNC:HGNC:2121 xref: UniGene:Hs.506659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056839 ! Q6LEE7_HUMAN relationship: codes_for CCO:B0058454 ! CML1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017395 name: CAMTA1_human def: "Calmodulin-binding transcription activator 1 gene" [UniProtKB:Q9Y6Y1] synonym: "KIAA0833" EXACT [UniProtKB:Q9Y6Y1] xref: EMBL:AB020640 xref: EMBL:AL359881 xref: EMBL:AL365194 xref: EMBL:AL590128 xref: EMBL:AL596210 xref: EMBL:Z97635 xref: EMBL:Z98052 xref: EMBL:Z98884 xref: HGNC:HGNC:18806 xref: UniGene:Hs.397705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059420 ! CMTA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017396 name: CAMTA2_human def: "Calmodulin-binding transcription activator 2 gene" [UniProtKB:O94983] synonym: "KIAA0909" EXACT [UniProtKB:O94983] xref: EMBL:AB020716 xref: EMBL:AL831849 xref: EMBL:AL833974 xref: EMBL:BC010050 xref: EMBL:BC016163 xref: HGNC:HGNC:18807 xref: UniGene:Hs.632242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054714 ! CMTA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017397 name: C14orf43_human def: "Uncharacterized protein C14orf43 gene" [UniProtKB:Q6PJG2] synonym: "C14orf117" EXACT [UniProtKB:Q6PJG2] xref: EMBL:AC006146 xref: EMBL:AK127785 xref: EMBL:BC006511 xref: EMBL:BC009202 xref: EMBL:BC015668 xref: HGNC:HGNC:19853 xref: UniGene:Hs.656506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056920 ! CN043_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017398 name: CNBP_human def: "Cellular nucleic acid-binding protein gene" [UniProtKB:P62633] synonym: "RNF163" EXACT [UniProtKB:P62633] synonym: "ZNF9" EXACT [UniProtKB:P62633] xref: EMBL:AK054592 xref: EMBL:AY329622 xref: EMBL:BC000288 xref: EMBL:BC014911 xref: EMBL:BC093058 xref: EMBL:M28372 xref: EMBL:U19765 xref: HGNC:HGNC:13164 xref: UniGene:Hs.518249 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055620 ! CNBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017399 name: CNGA3_human def: "Cyclic nucleotide-gated cation channel alpha-3 gene" [UniProtKB:Q16281] synonym: "CNCG3" EXACT [UniProtKB:Q16281] xref: EMBL:AC092675 xref: EMBL:AF065314 xref: EMBL:BC096298 xref: EMBL:BC096300 xref: EMBL:S76069 xref: HGNC:HGNC:2150 xref: UniGene:Hs.234785 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056132 ! CNGA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017400 name: CNGB3_human def: "Cyclic nucleotide-gated cation channel beta-3 gene" [UniProtKB:Q9NQW8] xref: EMBL:AF228520 xref: EMBL:AF272900 xref: HGNC:HGNC:2153 xref: UniGene:Hs.154433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058877 ! CNGB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017401 name: CNIH2_human def: "Protein cornichon homolog 2 gene" [UniProtKB:Q6PI25] synonym: "CNIL" EXACT [UniProtKB:Q6PI25] xref: EMBL:BC047953 xref: HGNC:HGNC:28744 xref: UniGene:Hs.437072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056908 ! CNIH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017402 name: CNIH3_human def: "Protein cornichon homolog 3 gene" [UniProtKB:Q8TBE1] xref: EMBL:AC096537 xref: EMBL:AK096312 xref: EMBL:AL596330 xref: EMBL:BC022780 xref: HGNC:HGNC:26802 xref: UniGene:Hs.28659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057902 ! CNIH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017403 name: CNIH4_human def: "Protein cornichon homolog 4 gene" [UniProtKB:Q9P003] synonym: "HSPC163" EXACT [UniProtKB:Q9P003] xref: EMBL:AC099790 xref: EMBL:AF161512 xref: EMBL:AL136930 xref: EMBL:BC000573 xref: HGNC:HGNC:25013 xref: UniGene:Hs.445890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053869 ! A6NJ96_HUMAN relationship: codes_for CCO:B0053897 ! A6NLH6_HUMAN relationship: codes_for CCO:B0059024 ! CNIH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017404 name: CNIH_human def: "Protein cornichon homolog gene" [UniProtKB:O95406] synonym: "CNIL" EXACT [UniProtKB:O95406] synonym: "UNQ155/PRO181" EXACT [UniProtKB:O95406] xref: EMBL:AF031379 xref: EMBL:AF070654 xref: EMBL:AF104398 xref: EMBL:AL359792 xref: EMBL:AY358635 xref: EMBL:BC103741 xref: HGNC:HGNC:19431 xref: UniGene:Hs.294603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054067 ! A8MVW4_HUMAN relationship: codes_for CCO:B0054759 ! CNIH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017405 name: CNKSR1_human def: "Connector enhancer of kinase suppressor of ras 1 gene" [UniProtKB:Q969H4] synonym: "CNK1" EXACT [UniProtKB:Q969H4] xref: EMBL:AF100153 xref: EMBL:BC011604 xref: EMBL:BC012797 xref: EMBL:BT006900 xref: HGNC:HGNC:19700 xref: UniGene:Hs.16232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058131 ! CNKR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017406 name: CNKSR2_human def: "Connector enhancer of kinase suppressor of ras 2 gene" [UniProtKB:Q8WXI2] synonym: "CNK2" EXACT [UniProtKB:Q8WXI2] synonym: "KIAA0902" EXACT [UniProtKB:Q8WXI2] synonym: "KSR2" EXACT [UniProtKB:Q8WXI2] xref: EMBL:AB020709 xref: EMBL:AF418269 xref: EMBL:AF418270 xref: EMBL:AL772392 xref: EMBL:AL807781 xref: EMBL:AL928874 xref: EMBL:BC126121 xref: EMBL:CH471074 xref: HGNC:HGNC:19701 xref: UniGene:Hs.632794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056454 ! Q5JPN0_HUMAN relationship: codes_for CCO:B0058022 ! CNKR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017407 name: CNKSR3_human def: "Connector enhancer of kinase suppressor of ras 3 gene" [UniProtKB:Q6P9H4] synonym: "MAGI1" EXACT [UniProtKB:Q6P9H4] xref: EMBL:AK055911 xref: EMBL:AL357075 xref: EMBL:AY328891 xref: EMBL:AY328892 xref: EMBL:AY328893 xref: EMBL:BC060761 xref: EMBL:CH471051 xref: HGNC:HGNC:23034 xref: UniGene:Hs.16064 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056898 ! CNKR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017408 name: CNOT3_human def: "CCR4-NOT transcription complex subunit 3 gene" [UniProtKB:O75175] synonym: "KIAA0691" EXACT [UniProtKB:O75175] synonym: "LENG2" EXACT [UniProtKB:O75175] synonym: "NOT3" EXACT [UniProtKB:O75175] xref: EMBL:AB014591 xref: EMBL:AF180474 xref: EMBL:AL133647 xref: EMBL:BC016474 xref: EMBL:CU151838 xref: EMBL:CU457734 xref: HGNC:HGNC:7879 xref: UniGene:Hs.343571 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054149 ! A9C4B1_HUMAN relationship: codes_for CCO:B0054193 ! B0V3I0_HUMAN relationship: codes_for CCO:B0054611 ! CNOT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017409 name: CNOT4_human def: "CCR4-NOT transcription complex subunit 4 gene" [UniProtKB:O95628] synonym: "NOT4" EXACT [UniProtKB:O95628] xref: EMBL:AF091094 xref: EMBL:AF180475 xref: EMBL:AK074671 xref: EMBL:AL389980 xref: EMBL:BC035590 xref: EMBL:U71267 xref: EMBL:U71268 xref: HGNC:HGNC:7880 xref: UniGene:Hs.490224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054775 ! CNOT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017410 name: CNR1_human def: "Cannabinoid receptor 1 gene" [UniProtKB:P21554] synonym: "CNR" EXACT [UniProtKB:P21554] xref: EMBL:AF107262 xref: EMBL:AL136096 xref: EMBL:AY225225 xref: EMBL:AY766182 xref: EMBL:BC074811 xref: EMBL:BC074812 xref: EMBL:BC095513 xref: EMBL:BC100968 xref: EMBL:BC100969 xref: EMBL:BC100970 xref: EMBL:BC100971 xref: EMBL:DQ067455 xref: EMBL:U73304 xref: EMBL:X54937 xref: EMBL:X81120 xref: EMBL:X81121 xref: HGNC:HGNC:2159 xref: UniGene:Hs.706619 xref: UniGene:Hs.75110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055133 ! CNR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017411 name: CNR2_human def: "Cannabinoid receptor 2 gene" [UniProtKB:P34972] xref: EMBL:AJ430063 xref: EMBL:AJ430064 xref: EMBL:AY242132 xref: EMBL:X74328 xref: HGNC:HGNC:2160 xref: UniGene:Hs.73037 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055273 ! CNR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017412 name: CNTNAP3B_human def: "Contactin-associated protein-like 3B precursor gene" [UniProtKB:Q96NU0] synonym: "CASPR3B" EXACT [UniProtKB:Q96NU0] xref: EMBL:AK024257 xref: EMBL:AK054645 xref: EMBL:AL353791 xref: EMBL:BX649569 xref: EMBL:BX664735 xref: EMBL:CR788268 xref: HGNC:HGNC:32035 xref: UniGene:Hs.521495 xref: UniGene:Hs.604441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058313 ! CNT3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017413 name: CNTLN_human def: "Centlein gene" [UniProtKB:Q9NXG0] synonym: "C9orf101" EXACT [UniProtKB:Q9NXG0] synonym: "C9orf39" EXACT [UniProtKB:Q9NXG0] xref: EMBL:AK000283 xref: EMBL:AK021596 xref: EMBL:AK098502 xref: EMBL:AL133214 xref: EMBL:AL162725 xref: EMBL:AL354711 xref: EMBL:AL354738 xref: EMBL:AL590377 xref: HGNC:HGNC:23432 xref: UniGene:Hs.435381 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058952 ! CNTLN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017414 name: CNTN1_human def: "Contactin-1 precursor gene" [UniProtKB:Q12860] xref: EMBL:AK289544 xref: EMBL:AK289698 xref: EMBL:BC036569 xref: EMBL:U07819 xref: EMBL:U07820 xref: EMBL:Z21488 xref: HGNC:HGNC:2171 xref: UniGene:Hs.143434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055851 ! CNTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017415 name: CNTN4_human def: "Contactin-4 precursor gene" [UniProtKB:Q8IWV2] xref: EMBL:AF464063 xref: EMBL:AF549455 xref: EMBL:AY090737 xref: EMBL:BC026119 xref: HGNC:HGNC:2174 xref: UniGene:Hs.298705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057365 ! CNTN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017416 name: CNTN6_human def: "Contactin-6 precursor gene" [UniProtKB:Q9UQ52] xref: EMBL:AB003592 xref: EMBL:BC113118 xref: HGNC:HGNC:2176 xref: UniGene:Hs.387300 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059276 ! CNTN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017417 name: CNTNAP1_human def: "Contactin-associated protein 1 precursor gene" [UniProtKB:P78357] synonym: "CASPR" EXACT [UniProtKB:P78357] synonym: "NRXN4" EXACT [UniProtKB:P78357] xref: EMBL:U87223 xref: HGNC:HGNC:8011 xref: UniGene:Hs.408730 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055641 ! CNTP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017418 name: CNTNAP2_human def: "Contactin-associated protein-like 2 precursor gene" [UniProtKB:Q9UHC6] synonym: "CASPR2" EXACT [UniProtKB:Q9UHC6] synonym: "KIAA0868" EXACT [UniProtKB:Q9UHC6] xref: EMBL:AB020675 xref: EMBL:AF193613 xref: EMBL:AF318292 xref: EMBL:AF318298 xref: EMBL:AF319045 xref: EMBL:BC093780 xref: EMBL:BC113373 xref: EMBL:CR933671 xref: HGNC:HGNC:13830 xref: UniGene:Hs.655684 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059135 ! CNTP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017419 name: CNTNAP3_human def: "Contactin-associated protein-like 3 precursor gene" [UniProtKB:Q9BZ76] synonym: "CASPR3" EXACT [UniProtKB:Q9BZ76] synonym: "KIAA1714" EXACT [UniProtKB:Q9BZ76] xref: EMBL:AB051501 xref: EMBL:AF333769 xref: EMBL:AL162501 xref: EMBL:AL353729 xref: HGNC:HGNC:13834 xref: UniGene:Hs.521495 xref: UniGene:Hs.604441 xref: UniGene:Hs.658328 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053784 ! A6NC89_HUMAN relationship: codes_for CCO:B0054251 ! B1AMA2_HUMAN relationship: codes_for CCO:B0058590 ! CNTP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017420 name: CNTNAP5_human def: "Contactin-associated protein-like 5 precursor gene" [UniProtKB:Q8WYK1] synonym: "CASPR5" EXACT [UniProtKB:Q8WYK1] xref: EMBL:AB077881 xref: EMBL:AC019105 xref: EMBL:AC019159 xref: EMBL:AC074362 xref: EMBL:AC079154 xref: EMBL:AC097715 xref: EMBL:AC104648 xref: EMBL:AK056528 xref: EMBL:CH471103 xref: HGNC:HGNC:18748 xref: UniGene:Hs.660653 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058042 ! CNTP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017421 name: COL1A2_human def: "Collagen alpha-2(I) chain precursor gene" [UniProtKB:P08123] xref: EMBL:AB004317 xref: EMBL:AC002528 xref: EMBL:AF004877 xref: EMBL:BC042586 xref: EMBL:BC054498 xref: EMBL:J00114 xref: EMBL:J03464 xref: EMBL:K01078 xref: EMBL:K02568 xref: EMBL:L47668 xref: EMBL:M21353 xref: EMBL:M21671 xref: EMBL:M22816 xref: EMBL:M22817 xref: EMBL:M28985 xref: EMBL:M35391 xref: EMBL:S41099 xref: EMBL:S96821 xref: EMBL:S98904 xref: EMBL:V00503 xref: EMBL:X02488 xref: EMBL:X55525 xref: EMBL:Y00724 xref: EMBL:Z74616 xref: HGNC:HGNC:2198 xref: UniGene:Hs.489142 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054920 ! CO1A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017422 name: COL3A1_human def: "Collagen alpha-1(III) chain precursor gene" [UniProtKB:P02461] xref: EMBL:AC066694 xref: EMBL:AY016295 xref: EMBL:AY054301 xref: EMBL:BC028178 xref: EMBL:M11134 xref: EMBL:M13146 xref: EMBL:M26939 xref: EMBL:M55603 xref: EMBL:M59227 xref: EMBL:M59312 xref: EMBL:S62925 xref: EMBL:S79877 xref: EMBL:X01655 xref: EMBL:X01742 xref: EMBL:X06700 xref: EMBL:X07240 xref: EMBL:X14420 xref: EMBL:X15332 xref: HGNC:HGNC:2201 xref: UniGene:Hs.443625 xref: UniGene:Hs.702420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054859 ! CO3A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017423 name: COL4A3_human def: "Collagen alpha-3(IV) chain precursor gene" [UniProtKB:Q01955] xref: EMBL:AB008496 xref: EMBL:AC079235 xref: EMBL:AC097662 xref: EMBL:AC107069 xref: EMBL:AF258351 xref: EMBL:AJ288487 xref: EMBL:AJ288488 xref: EMBL:AJ288489 xref: EMBL:AJ288490 xref: EMBL:AJ288491 xref: EMBL:AJ288492 xref: EMBL:AJ288493 xref: EMBL:AJ288494 xref: EMBL:AJ288495 xref: EMBL:AJ288496 xref: EMBL:AJ288497 xref: EMBL:AJ288498 xref: EMBL:AJ288499 xref: EMBL:AJ288500 xref: EMBL:AJ288501 xref: EMBL:AJ288502 xref: EMBL:AJ288503 xref: EMBL:AJ288504 xref: EMBL:AJ288505 xref: EMBL:AJ288506 xref: EMBL:AJ288507 xref: EMBL:AJ288508 xref: EMBL:AJ288509 xref: EMBL:AJ288510 xref: EMBL:AJ288511 xref: EMBL:AJ288512 xref: EMBL:AJ288513 xref: EMBL:AJ288514 xref: EMBL:AJ288515 xref: EMBL:AJ288516 xref: EMBL:AJ288517 xref: EMBL:AJ288518 xref: EMBL:AJ288519 xref: EMBL:AJ288520 xref: EMBL:AJ288521 xref: EMBL:AJ288522 xref: EMBL:AJ288523 xref: EMBL:AJ288524 xref: EMBL:AJ288525 xref: EMBL:AJ288526 xref: EMBL:AJ288527 xref: EMBL:AJ288528 xref: EMBL:AJ288529 xref: EMBL:AJ288530 xref: EMBL:AJ288531 xref: EMBL:AJ288532 xref: EMBL:AJ288533 xref: EMBL:AJ288534 xref: EMBL:AJ288535 xref: EMBL:AJ288536 xref: EMBL:AJ288537 xref: EMBL:AJ288538 xref: EMBL:L08650 xref: EMBL:M81379 xref: EMBL:M92993 xref: EMBL:S55790 xref: EMBL:U02519 xref: EMBL:U02520 xref: EMBL:X80031 xref: HGNC:HGNC:2204 xref: UniGene:Hs.570065 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055696 ! CO4A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017424 name: COL4A4_human def: "Collagen alpha-4(IV) chain precursor gene" [UniProtKB:P53420] xref: EMBL:AB008496 xref: EMBL:AC073149 xref: EMBL:AC079235 xref: EMBL:D17391 xref: EMBL:X81053 xref: EMBL:Y17397 xref: EMBL:Y17398 xref: EMBL:Y17399 xref: EMBL:Y17400 xref: EMBL:Y17401 xref: EMBL:Y17402 xref: EMBL:Y17403 xref: EMBL:Y17404 xref: EMBL:Y17405 xref: EMBL:Y17406 xref: EMBL:Y17407 xref: EMBL:Y17408 xref: EMBL:Y17409 xref: EMBL:Y17410 xref: EMBL:Y17411 xref: EMBL:Y17412 xref: EMBL:Y17413 xref: EMBL:Y17414 xref: EMBL:Y17415 xref: EMBL:Y17416 xref: EMBL:Y17417 xref: EMBL:Y17418 xref: EMBL:Y17419 xref: EMBL:Y17420 xref: EMBL:Y17421 xref: EMBL:Y17422 xref: EMBL:Y17423 xref: EMBL:Y17424 xref: EMBL:Y17425 xref: EMBL:Y17426 xref: EMBL:Y17427 xref: EMBL:Y17428 xref: EMBL:Y17429 xref: EMBL:Y17430 xref: EMBL:Y17431 xref: EMBL:Y17432 xref: EMBL:Y17433 xref: EMBL:Y17434 xref: EMBL:Y17435 xref: EMBL:Y17436 xref: EMBL:Y17437 xref: EMBL:Y17438 xref: EMBL:Y17439 xref: EMBL:Y17440 xref: EMBL:Y17441 xref: EMBL:Y17442 xref: EMBL:Y17443 xref: HGNC:HGNC:2206 xref: UniGene:Hs.591645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055509 ! CO4A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017425 name: C5_human def: "Complement C5 precursor gene" [UniProtKB:P01031] synonym: "CPAMD4" EXACT [UniProtKB:P01031] xref: EMBL:BC113738 xref: EMBL:BC113740 xref: EMBL:CH471090 xref: EMBL:DQ400449 xref: EMBL:M57729 xref: EMBL:M65134 xref: HGNC:HGNC:1331 xref: UniGene:Hs.494997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054830 ! CO5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017426 name: C9_human def: "Complement component C9 precursor gene" [UniProtKB:P02748] xref: EMBL:BC020721 xref: EMBL:J02833 xref: EMBL:K02766 xref: EMBL:X02176 xref: EMBL:Y08545 xref: EMBL:Y08546 xref: EMBL:Y08547 xref: EMBL:Y08548 xref: EMBL:Y08549 xref: EMBL:Y08550 xref: EMBL:Y08551 xref: EMBL:Y08552 xref: EMBL:Y08553 xref: EMBL:Y08554 xref: HGNC:HGNC:1358 xref: UniGene:Hs.654443 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054870 ! CO9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017427 name: EBF2_human def: "Transcription factor COE2 gene" [UniProtKB:Q9HAK2] synonym: "COE2" EXACT [UniProtKB:Q9HAK2] xref: EMBL:AC023566 xref: EMBL:AC090103 xref: EMBL:AK021562 xref: EMBL:AY700779 xref: EMBL:BC069665 xref: EMBL:BC069726 xref: EMBL:BC069747 xref: EMBL:BC069768 xref: EMBL:BC074794 xref: EMBL:BC113478 xref: EMBL:BC113504 xref: HGNC:HGNC:19090 xref: UniGene:Hs.491292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056696 ! Q66VZ3_HUMAN relationship: codes_for CCO:B0058764 ! COE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017428 name: EBF3_human def: "Transcription factor COE3 gene" [UniProtKB:Q9H4W6] synonym: "COE3" EXACT [UniProtKB:Q9H4W6] xref: EMBL:AL354950 xref: HGNC:HGNC:19087 xref: UniGene:Hs.699395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056590 ! Q5T6H8_HUMAN relationship: codes_for CCO:B0058720 ! COE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017429 name: EBF4_human def: "Transcription factor COE4 gene" [UniProtKB:Q9BQW3] synonym: "COE4" EXACT [UniProtKB:Q9BQW3] synonym: "KIAA1442" EXACT [UniProtKB:Q9BQW3] xref: EMBL:AB037863 xref: EMBL:AL035460 xref: HGNC:HGNC:29278 xref: UniGene:Hs.471955 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058483 ! COE4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017430 name: COG3_human def: "Conserved oligomeric Golgi complex subunit 3 gene" [UniProtKB:Q96JB2] synonym: "SEC34" EXACT [UniProtKB:Q96JB2] xref: EMBL:AF332595 xref: EMBL:AF349676 xref: EMBL:AL139326 xref: EMBL:AL606514 xref: EMBL:BC038953 xref: HGNC:HGNC:18619 xref: UniGene:Hs.507948 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058237 ! COG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017431 name: COG7_human def: "Conserved oligomeric Golgi complex subunit 7 gene" [UniProtKB:P83436] synonym: "UNQ3082/PRO10013" EXACT [UniProtKB:P83436] xref: EMBL:AY358632 xref: EMBL:BC000549 xref: EMBL:BC037563 xref: HGNC:HGNC:18622 xref: UniGene:Hs.185807 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055660 ! COG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017432 name: COL16A1_human def: "Collagen alpha-1(XVI) chain precursor gene" [UniProtKB:Q07092] synonym: "FP1572" EXACT [UniProtKB:Q07092] xref: EMBL:AB209571 xref: EMBL:AC114488 xref: EMBL:AF370368 xref: EMBL:M92642 xref: EMBL:S57132 xref: EMBL:X14963 xref: EMBL:X15038 xref: HGNC:HGNC:2193 xref: UniGene:Hs.368921 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055782 ! COGA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017433 name: COL18A1_human def: "Collagen alpha-1(XVIII) chain precursor gene" [UniProtKB:P39060] xref: EMBL:AF018081 xref: EMBL:AF018082 xref: EMBL:AF184060 xref: EMBL:AF333247 xref: EMBL:AF416592 xref: EMBL:AL163302 xref: EMBL:AY484967 xref: EMBL:AY484968 xref: EMBL:AY484969 xref: EMBL:AY484970 xref: EMBL:AY484971 xref: EMBL:BC033715 xref: EMBL:BC063833 xref: EMBL:BX322561 xref: EMBL:L22548 xref: HGNC:HGNC:2195 xref: UniGene:Hs.517356 xref: UniGene:Hs.84190 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055322 ! COIA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017434 name: COLEC12_human def: "Collectin-12 gene" [UniProtKB:Q5KU26] synonym: "CLP1" EXACT [UniProtKB:Q5KU26] synonym: "NSR2" EXACT [UniProtKB:Q5KU26] synonym: "SCARA4" EXACT [UniProtKB:Q5KU26] synonym: "SRCL" EXACT [UniProtKB:Q5KU26] xref: EMBL:AB005145 xref: EMBL:AB034251 xref: EMBL:AB038518 xref: EMBL:AB052103 xref: EMBL:AL713657 xref: EMBL:AP000915 xref: EMBL:AP005240 xref: EMBL:BC060789 xref: HGNC:HGNC:16016 xref: UniGene:Hs.464422 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056521 ! COL12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017435 name: COMMD7_human def: "COMM domain-containing protein 7 gene" [UniProtKB:Q86VX2] synonym: "C20orf92" EXACT [UniProtKB:Q86VX2] xref: EMBL:AK027893 xref: EMBL:AL035071 xref: EMBL:AY542162 xref: EMBL:BC000628 xref: EMBL:BC047440 xref: EMBL:BX640505 xref: EMBL:CR383702 xref: HGNC:HGNC:16223 xref: UniGene:Hs.408427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057268 ! COMD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017436 name: CORL2_human def: "Ladybird homeobox corepressor 1-like protein gene" [UniProtKB:Q2VWA4] synonym: "FUSSEL18" EXACT [UniProtKB:Q2VWA4] xref: EMBL:AC051635 xref: EMBL:AY669508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056234 ! CORL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017437 name: CPEB1_human def: "Cytoplasmic polyadenylation element-binding protein 1 gene" [UniProtKB:Q9BZB8] synonym: "CPEB" EXACT [UniProtKB:Q9BZB8] xref: EMBL:AF329402 xref: EMBL:AF329403 xref: EMBL:AK023265 xref: EMBL:BC035348 xref: EMBL:BC050629 xref: HGNC:HGNC:21744 xref: UniGene:Hs.547988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058593 ! CPEB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017438 name: CPEB2_human def: "Cytoplasmic polyadenylation element-binding protein 2 gene" [UniProtKB:Q7Z5Q1] xref: EMBL:AY247744 xref: EMBL:AY255519 xref: EMBL:BC103939 xref: EMBL:BC103940 xref: EMBL:BC103941 xref: EMBL:BC103942 xref: EMBL:BC105925 xref: HGNC:HGNC:21745 xref: UniGene:Hs.656937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057184 ! CPEB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017439 name: CPLX3_human def: "Complexin-3 precursor gene" [UniProtKB:Q8WVH0] synonym: "Nbla11589" EXACT [UniProtKB:Q8WVH0] xref: EMBL:AB072900 xref: EMBL:AK024055 xref: EMBL:AK074096 xref: EMBL:AY286501 xref: EMBL:BC018026 xref: HGNC:HGNC:27652 xref: UniGene:Hs.187694 xref: UniGene:Hs.620644 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057992 ! CPLX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017440 name: CPLX4_human def: "Complexin-4 precursor gene" [UniProtKB:Q7Z7G2] xref: EMBL:AK123184 xref: EMBL:AY286502 xref: EMBL:BC106887 xref: EMBL:BC106888 xref: EMBL:BX640655 xref: HGNC:HGNC:24330 xref: UniGene:Hs.449884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057214 ! CPLX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017441 name: CPN2_human def: "Carboxypeptidase N subunit 2 precursor gene" [UniProtKB:P22792] synonym: "ACBP" EXACT [UniProtKB:P22792] xref: EMBL:BC031569 xref: EMBL:BC042334 xref: EMBL:J05158 xref: HGNC:HGNC:2313 xref: UniGene:Hs.528368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055151 ! CPN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017442 name: CPT1A_human def: "Carnitine O-palmitoyltransferase 1, liver isoform gene" [UniProtKB:P50416] synonym: "CPT1" EXACT [UniProtKB:P50416] xref: EMBL:AJ420747 xref: EMBL:AJ420748 xref: EMBL:BC000185 xref: EMBL:BT009791 xref: EMBL:L39211 xref: HGNC:HGNC:2328 xref: UniGene:Hs.503043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055450 ! CPT1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017443 name: CPT1B_human def: "Carnitine O-palmitoyltransferase 1, muscle isoform gene" [UniProtKB:Q92523] synonym: "KIAA1670" EXACT [UniProtKB:Q92523] xref: EMBL:AB003286 xref: EMBL:AB051457 xref: EMBL:D87812 xref: EMBL:U62317 xref: EMBL:U62733 xref: EMBL:U66828 xref: EMBL:Y08682 xref: EMBL:Y08683 xref: HGNC:HGNC:2329 xref: UniGene:Hs.439777 xref: UniGene:Hs.654827 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058059 ! CPT1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017444 name: CPT2_human def: "Carnitine O-palmitoyltransferase 2, mitochondrial precursor gene" [UniProtKB:P23786] synonym: "CPT1" EXACT [UniProtKB:P23786] xref: EMBL:AL606760 xref: EMBL:BC002445 xref: EMBL:BC005172 xref: EMBL:M58581 xref: EMBL:U09642 xref: EMBL:U09643 xref: EMBL:U09644 xref: EMBL:U09645 xref: EMBL:U09646 xref: EMBL:U09648 xref: HGNC:HGNC:2330 xref: UniGene:Hs.705379 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055167 ! CPT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017445 name: C18orf32_human def: "Uncharacterized protein C18orf32 gene" [UniProtKB:Q8TCD1] xref: EMBL:AB097012 xref: EMBL:AK291882 xref: EMBL:BC022357 xref: EMBL:BC093004 xref: HGNC:HGNC:31690 xref: UniGene:Hs.293653 xref: UniGene:Hs.374588 xref: UniGene:Hs.485090 xref: UniGene:Hs.654638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057914 ! CR032_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017446 name: CREB3L1_human def: "cAMP-responsive element-binding protein 3-like protein 1 gene" [UniProtKB:Q96BA8] synonym: "OASIS" EXACT [UniProtKB:Q96BA8] synonym: "PSEC0238" EXACT [UniProtKB:Q96BA8] xref: EMBL:AB063321 xref: EMBL:AK075538 xref: EMBL:BC014097 xref: EMBL:BC015781 xref: HGNC:HGNC:18856 xref: UniGene:Hs.405961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058161 ! CR3L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017447 name: CREB3L2_human def: "cAMP-responsive element-binding protein 3-like protein 2 gene" [UniProtKB:Q70SY1] synonym: "BBF2H7" EXACT [UniProtKB:Q70SY1] xref: EMBL:AJ549092 xref: EMBL:AJ549387 xref: EMBL:AK131517 xref: EMBL:BC063666 xref: EMBL:BC110813 xref: EMBL:CH236950 xref: HGNC:HGNC:23720 xref: UniGene:Hs.490273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057093 ! CR3L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017448 name: CREB3L3_human def: "cAMP-responsive element-binding protein 3-like protein 3 gene" [UniProtKB:Q68CJ9] synonym: "CREBH" EXACT [UniProtKB:Q68CJ9] synonym: "HYST1481" EXACT [UniProtKB:Q68CJ9] xref: EMBL:AB050902 xref: EMBL:AB073612 xref: EMBL:AK172839 xref: EMBL:BC101504 xref: EMBL:BC101508 xref: HGNC:HGNC:18855 xref: UniGene:Hs.247744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056698 ! CR3L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017449 name: CREB3L4_human def: "cAMP-responsive element-binding protein 3-like protein 4 gene" [UniProtKB:Q8TEY5] synonym: "AIBZIP" EXACT [UniProtKB:Q8TEY5] synonym: "CREB4" EXACT [UniProtKB:Q8TEY5] synonym: "JAL" EXACT [UniProtKB:Q8TEY5] xref: EMBL:AB052778 xref: EMBL:AB052781 xref: EMBL:AF394167 xref: EMBL:AF468007 xref: EMBL:AK304665 xref: EMBL:AL358472 xref: EMBL:AY049977 xref: EMBL:BC038962 xref: EMBL:CH471121 xref: HGNC:HGNC:18854 xref: UniGene:Hs.372924 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056576 ! Q5T4L0_HUMAN relationship: codes_for CCO:B0056577 ! Q5T4L1_HUMAN relationship: codes_for CCO:B0057958 ! CR3L4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017450 name: CHRDL1_human def: "Chordin-like protein 1 precursor gene" [UniProtKB:Q9BU40] synonym: "NRLN1" EXACT [UniProtKB:Q9BU40] xref: EMBL:AL049176 xref: EMBL:AL591489 xref: EMBL:BC002909 xref: HGNC:HGNC:29861 xref: UniGene:Hs.496587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058518 ! CRDL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017451 name: CREB5_human def: "cAMP-responsive element-binding protein 5 gene" [UniProtKB:Q02930] synonym: "CREBPA" EXACT [UniProtKB:Q02930] xref: EMBL:AC003074 xref: EMBL:AC005013 xref: EMBL:AC005105 xref: EMBL:BC059400 xref: EMBL:L05515 xref: EMBL:L05911 xref: EMBL:L05912 xref: EMBL:L05913 xref: HGNC:HGNC:16844 xref: UniGene:Hs.437075 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018382 ! CREB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017452 name: CREG1_human def: "Protein CREG1 precursor gene" [UniProtKB:O75629] synonym: "CREG" EXACT [UniProtKB:O75629] synonym: "UNQ727/PRO1409" EXACT [UniProtKB:O75629] xref: EMBL:AF084523 xref: EMBL:AK095456 xref: EMBL:AL031733 xref: EMBL:AY359071 xref: EMBL:BC006786 xref: EMBL:BC008628 xref: HGNC:HGNC:2351 xref: UniGene:Hs.5710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054660 ! CREG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017453 name: CREM_human def: "cAMP-responsive element modulator gene" [UniProtKB:Q03060] xref: EMBL:AF069065 xref: EMBL:AF212158 xref: EMBL:AF213897 xref: EMBL:AF213898 xref: EMBL:AF213899 xref: EMBL:AF214665 xref: EMBL:AF217318 xref: EMBL:AL117336 xref: EMBL:AL157783 xref: EMBL:AY292864 xref: EMBL:BC017117 xref: EMBL:BC066342 xref: EMBL:BC090051 xref: EMBL:D14826 xref: EMBL:S68134 xref: EMBL:S68271 xref: EMBL:U44836 xref: EMBL:Z15159 xref: HGNC:HGNC:2352 xref: UniGene:Hs.200250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053986 ! A8MPQ2_HUMAN relationship: codes_for CCO:B0055719 ! CREM_HUMAN relationship: codes_for CCO:B0056599 ! Q5T9H8_HUMAN relationship: codes_for CCO:B0056600 ! Q5T9I5_HUMAN relationship: codes_for CCO:B0056680 ! Q5W1B2_HUMAN relationship: codes_for CCO:B0058152 ! Q96AG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017454 name: CRHR1_human def: "Corticotropin-releasing factor receptor 1 precursor gene" [UniProtKB:P34998] synonym: "CRFR" EXACT [UniProtKB:P34998] synonym: "CRFR1" EXACT [UniProtKB:P34998] synonym: "CRHR" EXACT [UniProtKB:P34998] xref: EMBL:AF039510 xref: EMBL:AF039511 xref: EMBL:AF039512 xref: EMBL:AF039513 xref: EMBL:AF039514 xref: EMBL:AF039515 xref: EMBL:AF039516 xref: EMBL:AF039517 xref: EMBL:AF039518 xref: EMBL:AF039519 xref: EMBL:AF039520 xref: EMBL:AF039521 xref: EMBL:AF039522 xref: EMBL:AF039523 xref: EMBL:AF180301 xref: EMBL:AY457172 xref: EMBL:L23332 xref: EMBL:L23333 xref: EMBL:U16273 xref: EMBL:X72304 xref: HGNC:HGNC:2357 xref: UniGene:Hs.417628 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055276 ! CRFR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017455 name: CRHR2_human def: "Corticotropin-releasing factor receptor 2 precursor gene" [UniProtKB:Q13324] synonym: "CRF2R" EXACT [UniProtKB:Q13324] synonym: "CRH2R" EXACT [UniProtKB:Q13324] xref: EMBL:AB065699 xref: EMBL:AC004976 xref: EMBL:AF011406 xref: EMBL:AF019381 xref: EMBL:AY449734 xref: EMBL:BC096830 xref: EMBL:U34587 xref: EMBL:Y10151 xref: HGNC:HGNC:2358 xref: UniGene:Hs.546246 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055898 ! CRFR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017456 name: CRH_human def: "Corticoliberin precursor gene" [UniProtKB:P06850] xref: EMBL:BC002599 xref: EMBL:BC011031 xref: EMBL:BT007453 xref: EMBL:V00571 xref: HGNC:HGNC:2355 xref: UniGene:Hs.75294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054906 ! CRF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017457 name: CRHBP_human def: "Corticotropin-releasing factor-binding protein precursor gene" [UniProtKB:P24387] synonym: "CRFBP" EXACT [UniProtKB:P24387] xref: EMBL:BC018038 xref: EMBL:S60697 xref: EMBL:X58022 xref: HGNC:HGNC:2356 xref: UniGene:Hs.115617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055170 ! CRHBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017458 name: CRIM1_human def: "Cysteine-rich motor neuron 1 protein precursor gene" [UniProtKB:Q9NZV1] synonym: "S52" EXACT [UniProtKB:Q9NZV1] synonym: "UNQ1886/PRO4330" EXACT [UniProtKB:Q9NZV1] xref: EMBL:AB209139 xref: EMBL:AF167706 xref: EMBL:AF168681 xref: EMBL:AY358371 xref: EMBL:BC111989 xref: EMBL:BC113371 xref: HGNC:HGNC:2359 xref: UniGene:Hs.699247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059020 ! CRIM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017459 name: CRKL_human def: "Crk-like protein gene" [UniProtKB:P46109] xref: EMBL:BC043500 xref: EMBL:CR456423 xref: EMBL:X59656 xref: HGNC:HGNC:2363 xref: UniGene:Hs.592205 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055377 ! CRKL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017460 name: CRK_human def: "Proto-oncogene C-crk gene" [UniProtKB:P46108] xref: EMBL:BC001718 xref: EMBL:BC008506 xref: EMBL:BT007277 xref: EMBL:D10656 xref: EMBL:S65701 xref: HGNC:HGNC:2362 xref: UniGene:Hs.638121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055376 ! CRK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017461 name: CRIPAK_human def: "Cysteine-rich PAK1 inhibitor gene" [UniProtKB:Q8N1N5] xref: EMBL:AK091762 xref: EMBL:AK096209 xref: HGNC:HGNC:26619 xref: UniGene:Hs.26410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057431 ! CRPAK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017462 name: CRTC1_human def: "CREB-regulated transcription coactivator 1 gene" [UniProtKB:Q6UUV9] synonym: "KIAA0616" EXACT [UniProtKB:Q6UUV9] synonym: "MECT1" EXACT [UniProtKB:Q6UUV9] synonym: "TORC1" EXACT [UniProtKB:Q6UUV9] synonym: "WAMTP1" EXACT [UniProtKB:Q6UUV9] xref: EMBL:AB014516 xref: EMBL:AC003107 xref: EMBL:AC004476 xref: EMBL:AC006123 xref: EMBL:AK024089 xref: EMBL:AY040323 xref: EMBL:AY040324 xref: EMBL:AY186997 xref: EMBL:AY186998 xref: EMBL:AY360171 xref: EMBL:BC017075 xref: EMBL:BC023614 xref: EMBL:BC028050 xref: EMBL:CH471106 xref: HGNC:HGNC:16062 xref: UniGene:Hs.371096 xref: UniGene:Hs.428214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056949 ! CRTC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017463 name: CRTC2_human def: "CREB-regulated transcription coactivator 2 gene" [UniProtKB:Q53ET0] synonym: "TORC2" EXACT [UniProtKB:Q53ET0] xref: EMBL:AK223559 xref: EMBL:AL358472 xref: EMBL:AY360172 xref: EMBL:BC053562 xref: HGNC:HGNC:27301 xref: UniGene:Hs.406392 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056349 ! CRTC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017464 name: CRTC3_human def: "CREB-regulated transcription coactivator 3 gene" [UniProtKB:Q6UUV7] synonym: "TORC3" EXACT [UniProtKB:Q6UUV7] xref: EMBL:AK025521 xref: EMBL:AK090443 xref: EMBL:AY360173 xref: EMBL:BC074730 xref: EMBL:BC074731 xref: HGNC:HGNC:26148 xref: UniGene:Hs.567572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056948 ! CRTC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017465 name: CRX_human def: "Cone-rod homeobox protein gene" [UniProtKB:O43186] synonym: "CORD2" EXACT [UniProtKB:O43186] xref: EMBL:AF024711 xref: EMBL:BC016664 xref: EMBL:BC053672 xref: EMBL:BT007364 xref: HGNC:HGNC:2383 xref: UniGene:Hs.617342 xref: UniGene:Hs.633434 xref: UniGene:Hs.639114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054456 ! CRX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017466 name: CRY1_human def: "Cryptochrome-1 gene" [UniProtKB:Q16526] synonym: "PHLL1" EXACT [UniProtKB:Q16526] xref: EMBL:BC030519 xref: EMBL:D83702 xref: EMBL:D84657 xref: HGNC:HGNC:2384 xref: UniGene:Hs.151573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056142 ! CRY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017467 name: CRY2_human def: "Cryptochrome-2 gene" [UniProtKB:Q49AN0] synonym: "KIAA0658" EXACT [UniProtKB:Q49AN0] xref: EMBL:AB014558 xref: EMBL:BC035161 xref: EMBL:BC041814 xref: HGNC:HGNC:2385 xref: UniGene:Hs.532491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056304 ! CRY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017468 name: CRYAA_human def: "Alpha-crystallin A chain gene" [UniProtKB:P02489] synonym: "CRYA1" EXACT [UniProtKB:P02489] synonym: "HSPB4" EXACT [UniProtKB:P02489] xref: EMBL:AP001748 xref: EMBL:BC069528 xref: EMBL:M35628 xref: EMBL:M35629 xref: EMBL:U05569 xref: EMBL:U66584 xref: EMBL:X14789 xref: HGNC:HGNC:2388 xref: UniGene:Hs.184085 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054860 ! CRYAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017469 name: CRYAB_human def: "Alpha-crystallin B chain gene" [UniProtKB:P02511] synonym: "CRYA2" EXACT [UniProtKB:P02511] xref: EMBL:AF007162 xref: EMBL:AK314029 xref: EMBL:BC007008 xref: EMBL:BT006770 xref: EMBL:CH471065 xref: EMBL:EF444955 xref: EMBL:M24906 xref: EMBL:M28638 xref: EMBL:S45630 xref: HGNC:HGNC:2389 xref: UniGene:Hs.408767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054861 ! CRYAB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017470 name: C19orf10_human def: "UPF0556 protein C19orf10 precursor gene" [UniProtKB:Q969H8] synonym: "IL25" EXACT [UniProtKB:Q969H8] xref: EMBL:AC005339 xref: EMBL:AC005594 xref: EMBL:AL365373 xref: EMBL:AL365374 xref: EMBL:BC003639 xref: EMBL:BC010129 xref: EMBL:BC014655 xref: HGNC:HGNC:16948 xref: UniGene:Hs.465645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058132 ! CS010_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017471 name: CSDE1_human def: "Cold shock domain-containing protein E1 gene" [UniProtKB:O75534] synonym: "D1S155E" EXACT [UniProtKB:O75534] synonym: "KIAA0885" EXACT [UniProtKB:O75534] synonym: "NRU" EXACT [UniProtKB:O75534] synonym: "UNR" EXACT [UniProtKB:O75534] xref: EMBL:AB020692 xref: EMBL:AF070542 xref: EMBL:AF077054 xref: EMBL:AL096773 xref: EMBL:BC032446 xref: EMBL:CR749378 xref: HGNC:HGNC:29905 xref: UniGene:Hs.705404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054648 ! CSDE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017472 name: KCNIP3_human def: "Calsenilin gene" [UniProtKB:Q9Y2W7] synonym: "CSEN" EXACT [UniProtKB:Q9Y2W7] synonym: "DREAM" EXACT [UniProtKB:Q9Y2W7] synonym: "KCHIP3" EXACT [UniProtKB:Q9Y2W7] xref: EMBL:AC009238 xref: EMBL:AF120102 xref: EMBL:AF199599 xref: EMBL:AF367022 xref: EMBL:AJ131730 xref: EMBL:BC012850 xref: EMBL:BT020075 xref: HGNC:HGNC:15523 xref: UniGene:Hs.437376 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020218 ! CSEN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017473 name: CSF1R_human def: "Macrophage colony-stimulating factor 1 receptor precursor gene" [UniProtKB:P07333] synonym: "FMS" EXACT [UniProtKB:P07333] xref: EMBL:M11067 xref: EMBL:M14002 xref: EMBL:M14193 xref: EMBL:M25786 xref: EMBL:U63963 xref: EMBL:U78096 xref: EMBL:X03663 xref: HGNC:HGNC:2433 xref: UniGene:Hs.654394 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054912 ! CSF1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017474 name: CSF2_human def: "Granulocyte-macrophage colony-stimulating factor precursor gene" [UniProtKB:P04141] synonym: "GMCSF" EXACT [UniProtKB:P04141] xref: EMBL:AC004511 xref: EMBL:AF373868 xref: EMBL:AF510855 xref: EMBL:BC108724 xref: EMBL:BC113999 xref: EMBL:M10663 xref: EMBL:M11220 xref: EMBL:M11734 xref: EMBL:M13207 xref: EMBL:X03021 xref: HGNC:HGNC:2434 xref: UniGene:Hs.1349 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054885 ! CSF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017475 name: CSF3R_human def: "Granulocyte colony-stimulating factor receptor precursor gene" [UniProtKB:Q99062] synonym: "GCSFR" EXACT [UniProtKB:Q99062] xref: EMBL:AY148100 xref: EMBL:BC053585 xref: EMBL:M59818 xref: EMBL:M59819 xref: EMBL:M59820 xref: EMBL:S71484 xref: EMBL:X55720 xref: EMBL:X55721 xref: HGNC:HGNC:2439 xref: UniGene:Hs.524517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058407 ! CSF3R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017476 name: CSF3_human def: "Granulocyte colony-stimulating factor precursor gene" [UniProtKB:P09919] synonym: "GCSF" EXACT [UniProtKB:P09919] xref: EMBL:AF388025 xref: EMBL:M13008 xref: EMBL:M17706 xref: EMBL:X03438 xref: EMBL:X03655 xref: EMBL:X03656 xref: HGNC:HGNC:2438 xref: UniGene:Hs.2233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054952 ! CSF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017477 name: CSH1_human def: "Chorionic somatomammotropin hormone precursor gene" [UniProtKB:P01243] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054844 ! CSH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017478 name: CSH2_human def: "Chorionic somatomammotropin hormone precursor gene" [UniProtKB:P01243] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054844 ! CSH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017479 name: CASKIN1_human def: "Caskin-1 gene" [UniProtKB:Q8WXD9] synonym: "KIAA1306" EXACT [UniProtKB:Q8WXD9] xref: EMBL:AB037727 xref: EMBL:AF451977 xref: HGNC:HGNC:20879 xref: UniGene:Hs.643537 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058015 ! CSKI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017480 name: COPS2_human def: "COP9 signalosome complex subunit 2 gene" [UniProtKB:P61201] synonym: "CSN2" EXACT [UniProtKB:P61201] synonym: "TRIP15" EXACT [UniProtKB:P61201] xref: EMBL:AF084260 xref: EMBL:AF100762 xref: EMBL:AF120268 xref: EMBL:AF212227 xref: EMBL:BC012629 xref: EMBL:CR542063 xref: EMBL:L40388 xref: HGNC:HGNC:30747 xref: UniGene:Hs.369614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055605 ! CSN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017481 name: CSPG4_human def: "Chondroitin sulfate proteoglycan 4 precursor gene" [UniProtKB:Q6UVK1] synonym: "MCSP" EXACT [UniProtKB:Q6UVK1] xref: EMBL:AY359468 xref: EMBL:X96753 xref: HGNC:HGNC:2466 xref: UniGene:Hs.513044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056950 ! CSPG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017482 name: CSPG5_human def: "Chondroitin sulfate proteoglycan 5 precursor gene" [UniProtKB:O95196] synonym: "CALEB" EXACT [UniProtKB:O95196] synonym: "NGC" EXACT [UniProtKB:O95196] xref: EMBL:AF059274 xref: EMBL:AF461087 xref: EMBL:AF461088 xref: EMBL:AF461089 xref: HGNC:HGNC:2467 xref: UniGene:Hs.45127 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054734 ! CSPG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017483 name: VN2R1P_human def: "Putative calcium-sensing receptor-like 1 gene" [UniProtKB:Q8NGV9] synonym: "CASRL1" EXACT [UniProtKB:Q8NGV9] synonym: "GPRC2B" EXACT [UniProtKB:Q8NGV9] xref: EMBL:AB065664 xref: HGNC:HGNC:30344 xref: UniGene:Hs.49530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057768 ! CSRL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017484 name: CSRNP2_human def: "Cysteine/serine-rich nuclear protein 2 gene" [UniProtKB:Q9H175] synonym: "C12orf22" EXACT [UniProtKB:Q9H175] synonym: "FAM130A1" EXACT [UniProtKB:Q9H175] synonym: "TAIP12" EXACT [UniProtKB:Q9H175] xref: EMBL:AB063302 xref: EMBL:AJ298133 xref: EMBL:BC017221 xref: HGNC:HGNC:16006 xref: UniGene:Hs.524425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058661 ! CSRN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017485 name: CSRNP3_human def: "Cysteine/serine-rich nuclear protein 3 gene" [UniProtKB:Q8WYN3] synonym: "FAM130A2" EXACT [UniProtKB:Q8WYN3] synonym: "TAIP2" EXACT [UniProtKB:Q8WYN3] xref: EMBL:AB063300 xref: EMBL:AC019140 xref: EMBL:AK021765 xref: EMBL:AK126129 xref: HGNC:HGNC:30729 xref: UniGene:Hs.470479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058046 ! CSRN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017486 name: CSRP2_human def: "Cysteine and glycine-rich protein 2 gene" [UniProtKB:Q16527] synonym: "LMO5" EXACT [UniProtKB:Q16527] synonym: "SMLIM" EXACT [UniProtKB:Q16527] xref: EMBL:BC000992 xref: EMBL:BT019913 xref: EMBL:U46006 xref: EMBL:U57646 xref: EMBL:U95018 xref: HGNC:HGNC:2470 xref: UniGene:Hs.530904 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056143 ! CSRP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017487 name: CTBP1_human def: "C-terminal-binding protein 1 gene" [UniProtKB:Q13363] synonym: "CTBP" EXACT [UniProtKB:Q13363] xref: EMBL:AF091555 xref: EMBL:BC011655 xref: EMBL:U37408 xref: HGNC:HGNC:2494 xref: UniGene:Hs.208597 xref: UniGene:Hs.594321 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021721 ! CTBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017488 name: CTBP2_human def: "C-terminal-binding protein 2 gene" [UniProtKB:P56545] xref: EMBL:AF016507 xref: EMBL:AF222711 xref: EMBL:AL596261 xref: EMBL:AL731571 xref: EMBL:AL833398 xref: EMBL:BC002486 xref: EMBL:BC047018 xref: EMBL:BC052276 xref: EMBL:BC072020 xref: EMBL:BT007012 xref: EMBL:CH471066 xref: HGNC:HGNC:2495 xref: UniGene:Hs.501345 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021723 ! CTBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017489 name: CTF1_human def: "Cardiotrophin-1 gene" [UniProtKB:Q16619] xref: EMBL:BC064416 xref: EMBL:U43030 xref: EMBL:U43031 xref: EMBL:U43032 xref: EMBL:U43033 xref: HGNC:HGNC:2499 xref: UniGene:Hs.483811 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056160 ! CTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017490 name: SLC44A2_human def: "Choline transporter-like protein 2 gene" [UniProtKB:Q8IWA5] synonym: "CTL2" EXACT [UniProtKB:Q8IWA5] synonym: "PSEC0210" EXACT [UniProtKB:Q8IWA5] xref: EMBL:AJ245621 xref: EMBL:AK075512 xref: EMBL:AL832517 xref: EMBL:AL832978 xref: EMBL:BC010617 xref: EMBL:BC040556 xref: HGNC:HGNC:17292 xref: UniGene:Hs.631631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057356 ! CTL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017491 name: CTGLF7_human def: "Centaurin-gamma-like family member 7 gene" [UniProtKB:Q5T2P9] xref: EMBL:AL391137 xref: HGNC:HGNC:23462 xref: UniGene:Hs.463017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056566 ! CTLF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017492 name: CTNND2_human def: "Catenin delta-2 gene" [UniProtKB:Q9UQB3] synonym: "NPRAP" EXACT [UniProtKB:Q9UQB3] xref: EMBL:AB013805 xref: EMBL:AC003089 xref: EMBL:AC003954 xref: EMBL:AC004633 xref: EMBL:AC004648 xref: EMBL:AC005367 xref: EMBL:AC005610 xref: EMBL:AC010433 xref: EMBL:AC010626 xref: EMBL:AC113390 xref: EMBL:AC127460 xref: EMBL:AF035302 xref: EMBL:U52351 xref: EMBL:U52828 xref: EMBL:U72665 xref: EMBL:U81004 xref: EMBL:U96136 xref: HGNC:HGNC:2516 xref: UniGene:Hs.314543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059277 ! CTND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017493 name: CTTNBP2_human def: "Cortactin-binding protein 2 gene" [UniProtKB:Q8WZ74] synonym: "C7orf8" EXACT [UniProtKB:Q8WZ74] synonym: "CORTBP2" EXACT [UniProtKB:Q8WZ74] synonym: "KIAA1758" EXACT [UniProtKB:Q8WZ74] xref: EMBL:AB051545 xref: EMBL:AC004240 xref: EMBL:AF377960 xref: EMBL:BC106000 xref: EMBL:DQ354388 xref: EMBL:DQ354389 xref: EMBL:DQ354390 xref: EMBL:DQ354391 xref: EMBL:DQ356257 xref: EMBL:DQ356259 xref: EMBL:DQ356260 xref: EMBL:DQ356261 xref: EMBL:DQ356262 xref: EMBL:DQ356264 xref: HGNC:HGNC:15679 xref: UniGene:Hs.592285 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058050 ! CTTB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017494 name: CX3CR1_human def: "CX3C chemokine receptor 1 gene" [UniProtKB:P49238] synonym: "CMKBRL1" EXACT [UniProtKB:P49238] synonym: "GPR13" EXACT [UniProtKB:P49238] xref: EMBL:AY016370 xref: EMBL:BC028078 xref: EMBL:U20350 xref: EMBL:U28934 xref: HGNC:HGNC:2558 xref: UniGene:Hs.78913 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055420 ! CX3C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017495 name: GJB6_human def: "Gap junction beta-6 protein gene" [UniProtKB:O95452] xref: EMBL:AJ005585 xref: EMBL:AK289592 xref: EMBL:AL355984 xref: EMBL:AY297110 xref: EMBL:AY789474 xref: EMBL:AY789475 xref: EMBL:AY789476 xref: EMBL:BC038934 xref: EMBL:CH471075 xref: HGNC:HGNC:4288 xref: UniGene:Hs.511757 xref: UniGene:Hs.706191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054764 ! CXB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017496 name: CXCL9_human def: "C-X-C motif chemokine 9 precursor gene" [UniProtKB:Q07325] synonym: "CMK" EXACT [UniProtKB:Q07325] synonym: "MIG" EXACT [UniProtKB:Q07325] synonym: "SCYB9" EXACT [UniProtKB:Q07325] xref: EMBL:BC063122 xref: EMBL:BC095396 xref: EMBL:X72755 xref: HGNC:HGNC:7098 xref: UniGene:Hs.77367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055783 ! CXCL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017497 name: IL8RA_human def: "High affinity interleukin-8 receptor A gene" [UniProtKB:P25024] synonym: "CMKAR1" EXACT [UniProtKB:P25024] synonym: "CXCR1" EXACT [UniProtKB:P25024] xref: EMBL:AB032728 xref: EMBL:AB032729 xref: EMBL:AB032730 xref: EMBL:AB032731 xref: EMBL:AB032732 xref: EMBL:AC097483 xref: EMBL:AY651785 xref: EMBL:AY916762 xref: EMBL:AY916763 xref: EMBL:AY916764 xref: EMBL:AY916765 xref: EMBL:AY916766 xref: EMBL:AY916769 xref: EMBL:AY916772 xref: EMBL:AY916773 xref: EMBL:BC028221 xref: EMBL:BC072397 xref: EMBL:CR541994 xref: EMBL:CR542029 xref: EMBL:L19591 xref: EMBL:L19592 xref: EMBL:M68932 xref: EMBL:U11870 xref: EMBL:X65858 xref: HGNC:HGNC:6026 xref: UniGene:Hs.194778 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055175 ! CXCR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017498 name: IL8RB_human def: "High affinity interleukin-8 receptor B gene" [UniProtKB:P25025] synonym: "CXCR2" EXACT [UniProtKB:P25025] xref: EMBL:AB032733 xref: EMBL:AB032734 xref: EMBL:AY714242 xref: EMBL:BC037961 xref: EMBL:L19593 xref: EMBL:M73969 xref: EMBL:M94582 xref: EMBL:M99412 xref: EMBL:U11869 xref: HGNC:HGNC:6027 xref: UniGene:Hs.846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055176 ! CXCR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017499 name: CXCR3_human def: "C-X-C chemokine receptor type 3 gene" [UniProtKB:P49682] synonym: "GPR9" EXACT [UniProtKB:P49682] xref: EMBL:AB032735 xref: EMBL:AB032736 xref: EMBL:AF469635 xref: EMBL:AY242128 xref: EMBL:BC034403 xref: EMBL:U32674 xref: EMBL:X95876 xref: EMBL:Z79783 xref: HGNC:HGNC:4540 xref: UniGene:Hs.198252 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055428 ! CXCR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017500 name: CXCR4_human def: "C-X-C chemokine receptor type 4 gene" [UniProtKB:P61073] xref: EMBL:AF005058 xref: EMBL:AF025375 xref: EMBL:AF052572 xref: EMBL:AF147204 xref: EMBL:AJ224869 xref: EMBL:AY242129 xref: EMBL:AY728138 xref: EMBL:BC020968 xref: EMBL:BT006660 xref: EMBL:D10924 xref: EMBL:L01639 xref: EMBL:L06797 xref: EMBL:M99293 xref: EMBL:X71635 xref: EMBL:Y14739 xref: HGNC:HGNC:2561 xref: UniGene:Hs.593413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055603 ! CXCR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017501 name: CXCR5_human def: "C-X-C chemokine receptor type 5 gene" [UniProtKB:P32302] synonym: "BLR1" EXACT [UniProtKB:P32302] synonym: "MDR15" EXACT [UniProtKB:P32302] xref: EMBL:X68149 xref: EMBL:X68829 xref: HGNC:HGNC:1060 xref: UniGene:Hs.113916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055260 ! CXCR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017502 name: CXCR6_human def: "C-X-C chemokine receptor type 6 gene" [UniProtKB:O00574] synonym: "BONZO" EXACT [UniProtKB:O00574] synonym: "STRL33" EXACT [UniProtKB:O00574] synonym: "TYMSTR" EXACT [UniProtKB:O00574] xref: EMBL:AF007545 xref: EMBL:AF029759 xref: EMBL:AY322543 xref: EMBL:BC033584 xref: EMBL:U73529 xref: EMBL:U73531 xref: EMBL:Y13248 xref: HGNC:HGNC:16647 xref: UniGene:Hs.34526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054333 ! CXCR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017503 name: CXCR7_human def: "C-X-C chemokine receptor type 7 gene" [UniProtKB:P25106] synonym: "CMKOR1" EXACT [UniProtKB:P25106] synonym: "GPR159" EXACT [UniProtKB:P25106] synonym: "RDC1" EXACT [UniProtKB:P25106] xref: EMBL:AC079611 xref: EMBL:AF030297 xref: EMBL:BC036661 xref: EMBL:DQ822477 xref: EMBL:M64749 xref: EMBL:U67784 xref: EMBL:U73141 xref: HGNC:HGNC:23692 xref: UniGene:Hs.471751 xref: UniGene:Hs.702052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055182 ! CXCR7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017504 name: CXCL10_human def: "C-X-C motif chemokine 10 precursor gene" [UniProtKB:P02778] synonym: "INP10" EXACT [UniProtKB:P02778] synonym: "SCYB10" EXACT [UniProtKB:P02778] xref: EMBL:BC010954 xref: EMBL:X02530 xref: HGNC:HGNC:10637 xref: UniGene:Hs.632586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054875 ! CXL10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017505 name: CXCL11_human def: "C-X-C motif chemokine 11 precursor gene" [UniProtKB:O14625] synonym: "ITAC" EXACT [UniProtKB:O14625] synonym: "SCYB11" EXACT [UniProtKB:O14625] synonym: "SCYB9B" EXACT [UniProtKB:O14625] xref: EMBL:AF002985 xref: EMBL:AF030514 xref: EMBL:AF053972 xref: EMBL:AF077867 xref: EMBL:BC005292 xref: EMBL:BC012532 xref: EMBL:BC110986 xref: EMBL:BT006787 xref: EMBL:U59286 xref: EMBL:U66096 xref: EMBL:Y15220 xref: EMBL:Y15221 xref: HGNC:HGNC:10638 xref: UniGene:Hs.632592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054359 ! CXL11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017506 name: CXXC1_human def: "CpG-binding protein gene" [UniProtKB:Q9P0U4] synonym: "CFP1" EXACT [UniProtKB:Q9P0U4] synonym: "CGBP" EXACT [UniProtKB:Q9P0U4] synonym: "PCCX1" EXACT [UniProtKB:Q9P0U4] synonym: "PHF18" EXACT [UniProtKB:Q9P0U4] xref: EMBL:AB031069 xref: EMBL:AF149758 xref: EMBL:AL136862 xref: EMBL:BC014940 xref: EMBL:BC015733 xref: EMBL:BC029922 xref: HGNC:HGNC:24343 xref: UniGene:Hs.180933 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059034 ! CXXC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017507 name: CXXC4_human def: "CXXC-type zinc finger protein 4 gene" [UniProtKB:Q9H2H0] synonym: "IDAX" EXACT [UniProtKB:Q9H2H0] xref: EMBL:AC093628 xref: EMBL:AF272159 xref: EMBL:BC119751 xref: EMBL:BC119752 xref: EMBL:CH471057 xref: HGNC:HGNC:24593 xref: UniGene:Hs.12248 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058686 ! CXXC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017508 name: CYCS_human def: "Cytochrome c gene" [UniProtKB:P99999] synonym: "CYC" EXACT [UniProtKB:P99999] xref: EMBL:AC007487 xref: EMBL:AL713681 xref: EMBL:BC005299 xref: EMBL:BC008475 xref: EMBL:BC008477 xref: EMBL:BC009578 xref: EMBL:BC009579 xref: EMBL:BC009582 xref: EMBL:BC009587 xref: EMBL:BC009602 xref: EMBL:BC009607 xref: EMBL:BC014359 xref: EMBL:BC014361 xref: EMBL:BC015130 xref: EMBL:BC016006 xref: EMBL:BC021994 xref: EMBL:BC022330 xref: EMBL:BC067222 xref: EMBL:BC068464 xref: EMBL:BC070156 xref: EMBL:BC070346 xref: EMBL:BC071761 xref: EMBL:BT006946 xref: EMBL:CH236948 xref: EMBL:M22877 xref: HGNC:HGNC:19986 xref: UniGene:Hs.437060 xref: UniGene:Hs.617193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055677 ! CYC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017509 name: CYTH1_human def: "Cytohesin-1 gene" [UniProtKB:Q15438] synonym: "D17S811E" EXACT [UniProtKB:Q15438] synonym: "PSCD1" EXACT [UniProtKB:Q15438] xref: EMBL:AC022966 xref: EMBL:AF125350 xref: EMBL:AF125351 xref: EMBL:AF125352 xref: EMBL:AF125353 xref: EMBL:AF125354 xref: EMBL:AF125355 xref: EMBL:AF125356 xref: EMBL:AF125357 xref: EMBL:AF125358 xref: EMBL:AF125359 xref: EMBL:AF125360 xref: EMBL:AF125361 xref: EMBL:AF125362 xref: EMBL:BC038385 xref: EMBL:BC050452 xref: EMBL:M85169 xref: HGNC:HGNC:9501 xref: UniGene:Hs.191215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056063 ! CYH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017510 name: CYTH2_human def: "Cytohesin-2 gene" [UniProtKB:Q99418] synonym: "ARNO" EXACT [UniProtKB:Q99418] synonym: "PSCD2" EXACT [UniProtKB:Q99418] synonym: "PSCD2L" EXACT [UniProtKB:Q99418] xref: EMBL:BC004361 xref: EMBL:BC038713 xref: EMBL:U70728 xref: EMBL:X99753 xref: HGNC:HGNC:9502 xref: UniGene:Hs.144011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058410 ! CYH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017511 name: CYTH3_human def: "Cytohesin-3 gene" [UniProtKB:O43739] synonym: "ARNO3" EXACT [UniProtKB:O43739] synonym: "GRP1" EXACT [UniProtKB:O43739] synonym: "PSCD3" EXACT [UniProtKB:O43739] xref: EMBL:AJ005197 xref: EMBL:AJ223957 xref: EMBL:BC028717 xref: HGNC:HGNC:9504 xref: UniGene:Hs.487479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054516 ! CYH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017512 name: CYTH4_human def: "Cytohesin-4 gene" [UniProtKB:Q9UIA0] synonym: "CYT4" EXACT [UniProtKB:Q9UIA0] synonym: "PSCD4" EXACT [UniProtKB:Q9UIA0] xref: EMBL:AF075458 xref: EMBL:AF125349 xref: EMBL:BC041161 xref: EMBL:CR456551 xref: EMBL:Z94160 xref: HGNC:HGNC:9505 xref: UniGene:Hs.170944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059155 ! CYH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017513 name: CYR61_human def: "Protein CYR61 precursor gene" [UniProtKB:O00622] synonym: "CCN1" EXACT [UniProtKB:O00622] synonym: "GIG1" EXACT [UniProtKB:O00622] synonym: "IGFBP10" EXACT [UniProtKB:O00622] xref: EMBL:AF003114 xref: EMBL:AF003594 xref: EMBL:AF031385 xref: EMBL:AF307860 xref: EMBL:AY443495 xref: EMBL:BC001271 xref: EMBL:BC009199 xref: EMBL:BC016952 xref: EMBL:U62015 xref: EMBL:Y11307 xref: EMBL:Y12084 xref: EMBL:Z98053 xref: HGNC:HGNC:2654 xref: UniGene:Hs.8867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054337 ! CYR61_HUMAN relationship: codes_for CCO:B0059157 ! Q9UID7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017514 name: CYTL1_human def: "Cytokine-like protein 1 precursor gene" [UniProtKB:Q9NRR1] synonym: "C4orf4" EXACT [UniProtKB:Q9NRR1] synonym: "UNQ1942/PRO4425" EXACT [UniProtKB:Q9NRR1] xref: EMBL:AF193766 xref: EMBL:AY359101 xref: EMBL:BC031391 xref: HGNC:HGNC:24435 xref: UniGene:Hs.13872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058902 ! CYTL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017515 name: DEFB103A_human def: "Beta-defensin 103 precursor gene" [UniProtKB:P81534] synonym: "BD3" EXACT [UniProtKB:P81534] synonym: "DEFB103" EXACT [UniProtKB:P81534] synonym: "DEFB3" EXACT [UniProtKB:P81534] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055655 ! D103A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017516 name: DEFB103B_human def: "Beta-defensin 103 precursor gene" [UniProtKB:P81534] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055655 ! D103A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017517 name: DAB2_human def: "Disabled homolog 2 gene" [UniProtKB:P98082] synonym: "DOC2" EXACT [UniProtKB:P98082] xref: EMBL:AC008916 xref: EMBL:AF188298 xref: EMBL:AF205890 xref: EMBL:BC003064 xref: EMBL:CH471119 xref: EMBL:L16886 xref: EMBL:U39050 xref: EMBL:U41111 xref: EMBL:U53446 xref: HGNC:HGNC:2662 xref: UniGene:Hs.481980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055668 ! DAB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017518 name: DACH2_human def: "Dachshund homolog 2 gene" [UniProtKB:Q96NX9] xref: EMBL:AF428101 xref: EMBL:AK055953 xref: EMBL:AK091842 xref: EMBL:AL834456 xref: HGNC:HGNC:16814 xref: UniGene:Hs.86603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058314 ! DACH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017519 name: DACT1_human def: "Dapper homolog 1 gene" [UniProtKB:Q9NYF0] synonym: "DPR1" EXACT [UniProtKB:Q9NYF0] synonym: "HNG3" EXACT [UniProtKB:Q9NYF0] xref: EMBL:AF251079 xref: EMBL:AL133312 xref: EMBL:BK000256 xref: EMBL:BX161433 xref: HGNC:HGNC:17748 xref: UniGene:Hs.48950 xref: UniGene:Hs.701729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058960 ! DACT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017520 name: DAD1_human def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 gene" [UniProtKB:P61803] xref: EMBL:AY259117 xref: EMBL:BC007403 xref: EMBL:BC009798 xref: EMBL:CR407682 xref: EMBL:CR542204 xref: EMBL:D15057 xref: EMBL:U84212 xref: EMBL:U84213 xref: HGNC:HGNC:2664 xref: UniGene:Hs.82890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055612 ! DAD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017521 name: DAP_human def: "Death-associated protein 1 gene" [UniProtKB:P51397] synonym: "DAP1" EXACT [UniProtKB:P51397] xref: EMBL:AY266680 xref: EMBL:BC002726 xref: EMBL:X76105 xref: HGNC:HGNC:2672 xref: UniGene:Hs.75189 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055463 ! DAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017522 name: CCDC88C_human def: "Protein Daple gene" [UniProtKB:Q9P219] synonym: "DAPLE" EXACT [UniProtKB:Q9P219] synonym: "KIAA1509" EXACT [UniProtKB:Q9P219] xref: EMBL:AB040942 xref: EMBL:AL133153 xref: EMBL:AL135818 xref: EMBL:AL833046 xref: EMBL:BC028565 xref: EMBL:BC035914 xref: EMBL:BX248302 xref: EMBL:CQ719279 xref: HGNC:HGNC:19967 xref: UniGene:Hs.525536 xref: UniGene:Hs.693723 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059050 ! DAPLE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017523 name: DAPP1_human def: "Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide gene" [UniProtKB:Q9UN19] synonym: "BAM32" EXACT [UniProtKB:Q9UN19] synonym: "HSPC066" EXACT [UniProtKB:Q9UN19] xref: EMBL:AF161551 xref: EMBL:AF163254 xref: EMBL:AF178987 xref: EMBL:AF186022 xref: EMBL:AL713793 xref: EMBL:BC012924 xref: HGNC:HGNC:16500 xref: UniGene:Hs.436271 xref: UniGene:Hs.651566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059245 ! DAPP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017524 name: DAZL_human def: "Deleted in azoospermia-like gene" [UniProtKB:Q92904] synonym: "DAZH" EXACT [UniProtKB:Q92904] synonym: "DAZL1" EXACT [UniProtKB:Q92904] synonym: "DAZLA" EXACT [UniProtKB:Q92904] synonym: "SPGYLA" EXACT [UniProtKB:Q92904] xref: EMBL:BC027595 xref: EMBL:U65918 xref: EMBL:U66078 xref: EMBL:U66726 xref: EMBL:U77467 xref: EMBL:U77468 xref: EMBL:U77469 xref: EMBL:U77470 xref: EMBL:U77471 xref: EMBL:U77472 xref: EMBL:U77473 xref: EMBL:U77474 xref: EMBL:U77475 xref: EMBL:U77476 xref: HGNC:HGNC:2685 xref: UniGene:Hs.131179 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058111 ! DAZL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017525 name: DIABLO_human def: "Diablo homolog, mitochondrial precursor gene" [UniProtKB:Q9NR28] synonym: "SMAC" EXACT [UniProtKB:Q9NR28] xref: EMBL:AF262240 xref: EMBL:AF298770 xref: EMBL:AK024768 xref: EMBL:AK057778 xref: EMBL:BC004417 xref: EMBL:BC011909 xref: HGNC:HGNC:21528 xref: UniGene:Hs.169611 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058884 ! DBLOH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017526 name: DBNL_human def: "Drebrin-like protein gene" [UniProtKB:Q9UJU6] synonym: "CMAP" EXACT [UniProtKB:Q9UJU6] synonym: "PP5423" EXACT [UniProtKB:Q9UJU6] synonym: "SH3P7" EXACT [UniProtKB:Q9UJU6] xref: EMBL:AF077353 xref: EMBL:AF151364 xref: EMBL:AF197060 xref: EMBL:AF218020 xref: EMBL:AF250287 xref: EMBL:AK027367 xref: EMBL:BC011677 xref: EMBL:BC031687 xref: EMBL:CH236960 xref: EMBL:CH471128 xref: EMBL:CR457167 xref: HGNC:HGNC:2696 xref: UniGene:Hs.436500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059177 ! DBNL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017527 name: DBP_human def: "D site-binding protein gene" [UniProtKB:Q10586] xref: EMBL:BC011965 xref: EMBL:BT006836 xref: EMBL:D28468 xref: EMBL:U06936 xref: EMBL:U48212 xref: EMBL:U48213 xref: EMBL:U79283 xref: HGNC:HGNC:2697 xref: UniGene:Hs.414480 xref: UniGene:Hs.528006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055834 ! DBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017528 name: DBX2_human def: "Homeobox protein DBX2 gene" [UniProtKB:Q6ZNG2] xref: EMBL:AK131230 xref: HGNC:HGNC:33186 xref: UniGene:Hs.302764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057024 ! DBX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017529 name: DCBLD2_human def: "Discoidin, CUB and LCCL domain-containing protein 2 precursor gene" [UniProtKB:Q96PD2] synonym: "CLCP1" EXACT [UniProtKB:Q96PD2] synonym: "ESDN" EXACT [UniProtKB:Q96PD2] xref: EMBL:AB073146 xref: EMBL:AF387547 xref: EMBL:BC029658 xref: HGNC:HGNC:24627 xref: UniGene:Hs.203691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058328 ! DCBD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017530 name: DCDC1_human def: "Doublecortin domain-containing protein 1 gene" [UniProtKB:P59894] xref: EMBL:AL137804 xref: EMBL:AL162614 xref: EMBL:AY247970 xref: HGNC:HGNC:20625 xref: UniGene:Hs.127405 xref: UniGene:Hs.592000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055591 ! DCDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017531 name: DCDC5_human def: "Doublecortin domain-containing protein 5 gene" [UniProtKB:Q6ZRR9] synonym: "KIAA1493" EXACT [UniProtKB:Q6ZRR9] xref: EMBL:AK128035 xref: EMBL:AL135932 xref: HGNC:HGNC:24799 xref: UniGene:Hs.530438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057041 ! DCDC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017532 name: DCLK1_human def: "Serine/threonine-protein kinase DCLK1 gene" [UniProtKB:O15075] synonym: "DCAMKL1" EXACT [UniProtKB:O15075] synonym: "DCDC3A" EXACT [UniProtKB:O15075] synonym: "KIAA0369" EXACT [UniProtKB:O15075] xref: EMBL:AB002367 xref: EMBL:AL157694 xref: EMBL:AL157760 xref: EMBL:AL160392 xref: EMBL:AL390029 xref: EMBL:BC152456 xref: EMBL:CH471075 xref: HGNC:HGNC:2700 xref: UniGene:Hs.507755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030613 ! DCLK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017533 name: DCLK2_human def: "Serine/threonine-protein kinase DCLK2 gene" [UniProtKB:Q8N568] synonym: "DCAMKL2" EXACT [UniProtKB:Q8N568] synonym: "DCDC3B" EXACT [UniProtKB:Q8N568] synonym: "DCK2" EXACT [UniProtKB:Q8N568] xref: EMBL:AB209181 xref: EMBL:AC093748 xref: EMBL:AC105343 xref: EMBL:AC108934 xref: EMBL:AC118064 xref: EMBL:AL834498 xref: HGNC:HGNC:19002 xref: UniGene:Hs.591683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030617 ! DCLK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017534 name: MLYCD_human def: "Malonyl-CoA decarboxylase, mitochondrial precursor gene" [UniProtKB:O95822] xref: EMBL:AF090834 xref: EMBL:AF097832 xref: EMBL:AF153679 xref: EMBL:BC000286 xref: EMBL:BC052592 xref: HGNC:HGNC:7150 xref: UniGene:Hs.644610 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054797 ! DCMC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017535 name: ODC1_human def: "Ornithine decarboxylase gene" [UniProtKB:P11926] xref: EMBL:AY841870 xref: EMBL:BC025296 xref: EMBL:M16650 xref: EMBL:M20372 xref: EMBL:M31061 xref: EMBL:M33764 xref: EMBL:M34158 xref: EMBL:M81740 xref: EMBL:X16277 xref: EMBL:X53271 xref: EMBL:X55362 xref: HGNC:HGNC:8109 xref: UniGene:Hs.467701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054997 ! DCOR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017536 name: DCX_human def: "Neuronal migration protein doublecortin gene" [UniProtKB:O43602] synonym: "DBCN" EXACT [UniProtKB:O43602] synonym: "LISX" EXACT [UniProtKB:O43602] xref: EMBL:AF034634 xref: EMBL:AF040254 xref: EMBL:AF040255 xref: EMBL:AJ003112 xref: EMBL:AJ005592 xref: EMBL:AJ005593 xref: EMBL:AJ005594 xref: EMBL:AJ005595 xref: EMBL:AJ005596 xref: EMBL:AJ005597 xref: EMBL:AL031117 xref: EMBL:AL450490 xref: EMBL:BC027925 xref: EMBL:CH471120 xref: HGNC:HGNC:2714 xref: UniGene:Hs.34780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030615 ! DCX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017537 name: DDAH1_human def: "N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 gene" [UniProtKB:O94760] synonym: "DDAH" EXACT [UniProtKB:O94760] xref: EMBL:AB001915 xref: EMBL:BC033680 xref: EMBL:BC043235 xref: HGNC:HGNC:2715 xref: UniGene:Hs.379858 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054696 ! DDAH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017538 name: DDAH2_human def: "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 gene" [UniProtKB:O95865] synonym: "DDAH" EXACT [UniProtKB:O95865] synonym: "G6A" EXACT [UniProtKB:O95865] synonym: "NG30" EXACT [UniProtKB:O95865] xref: EMBL:AF070667 xref: EMBL:AF087894 xref: EMBL:AF129756 xref: EMBL:AJ012008 xref: EMBL:AL662899 xref: EMBL:AL670886 xref: EMBL:AL844216 xref: EMBL:BA000025 xref: EMBL:BC001435 xref: EMBL:BX248244 xref: EMBL:CH471081 xref: EMBL:CR354443 xref: EMBL:CR759787 xref: EMBL:CR936239 xref: HGNC:HGNC:2716 xref: UniGene:Hs.247362 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054801 ! DDAH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017539 name: DDEF1_human def: "130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein gene" [UniProtKB:Q9ULH1] synonym: "ASAP1" EXACT [UniProtKB:Q9ULH1] synonym: "KIAA1249" EXACT [UniProtKB:Q9ULH1] xref: EMBL:AB033075 xref: EMBL:AC009682 xref: EMBL:AC103725 xref: EMBL:AC131568 xref: EMBL:AC139019 xref: EMBL:BX537768 xref: HGNC:HGNC:2720 xref: UniGene:Hs.655552 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059225 ! DDEF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017540 name: DDEF2_human def: "Development and differentiation-enhancing factor 2 gene" [UniProtKB:O43150] synonym: "KIAA0400" EXACT [UniProtKB:O43150] xref: EMBL:AB007860 xref: EMBL:BC063308 xref: HGNC:HGNC:2721 xref: UniGene:Hs.555902 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054450 ! DDEF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017541 name: DDEFL1_human def: "Development and differentiation-enhancing factor-like 1 gene" [UniProtKB:Q8TDY4] synonym: "UPLC1" EXACT [UniProtKB:Q8TDY4] xref: EMBL:AB056749 xref: EMBL:AK000206 xref: EMBL:AL021154 xref: EMBL:AL357134 xref: EMBL:BC052305 xref: EMBL:BC060786 xref: HGNC:HGNC:14987 xref: UniGene:Hs.437379 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057946 ! DDFL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017542 name: DDR2_human def: "Discoidin domain-containing receptor 2 precursor gene" [UniProtKB:Q16832] synonym: "NTRKR3" EXACT [UniProtKB:Q16832] synonym: "TKT" EXACT [UniProtKB:Q16832] synonym: "TYRO10" EXACT [UniProtKB:Q16832] xref: EMBL:AK095975 xref: EMBL:AK314388 xref: EMBL:AL445197 xref: EMBL:BC052998 xref: EMBL:CH471067 xref: EMBL:X74764 xref: HGNC:HGNC:2731 xref: UniGene:Hs.591469 xref: UniGene:Hs.593833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056178 ! DDR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017543 name: DDIT4L_human def: "DNA-damage-inducible transcript 4-like protein gene" [UniProtKB:Q96D03] synonym: "REDD2" EXACT [UniProtKB:Q96D03] synonym: "RTP801L" EXACT [UniProtKB:Q96D03] xref: EMBL:AK094236 xref: EMBL:AL832277 xref: EMBL:BC013592 xref: EMBL:CH471057 xref: HGNC:HGNC:30555 xref: UniGene:Hs.480378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058188 ! DDT4L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017544 name: DDIT4_human def: "DNA-damage-inducible transcript 4 protein gene" [UniProtKB:Q9NX09] synonym: "REDD1" EXACT [UniProtKB:Q9NX09] synonym: "RTP801" EXACT [UniProtKB:Q9NX09] xref: EMBL:AF335324 xref: EMBL:AK000507 xref: EMBL:AL136668 xref: EMBL:AL683820 xref: EMBL:AY090097 xref: EMBL:BC000708 xref: EMBL:BC007714 xref: EMBL:BC015236 xref: EMBL:CH471083 xref: HGNC:HGNC:24944 xref: UniGene:Hs.523012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058946 ! DDT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017545 name: DDX1_human def: "ATP-dependent RNA helicase DDX1 gene" [UniProtKB:Q92499] xref: EMBL:BC012132 xref: EMBL:BC053673 xref: EMBL:X70649 xref: HGNC:HGNC:2734 xref: UniGene:Hs.440599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058058 ! DDX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017546 name: DDX20_human def: "Probable ATP-dependent RNA helicase DDX20 gene" [UniProtKB:Q9UHI6] synonym: "DP103" EXACT [UniProtKB:Q9UHI6] synonym: "GEMIN3" EXACT [UniProtKB:Q9UHI6] xref: EMBL:AF106019 xref: EMBL:AF171063 xref: EMBL:AK001506 xref: EMBL:AL049557 xref: EMBL:AL133598 xref: EMBL:BC011556 xref: HGNC:HGNC:2743 xref: UniGene:Hs.591405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059141 ! DDX20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017547 name: DDX25_human def: "ATP-dependent RNA helicase DDX25 gene" [UniProtKB:Q9UHL0] synonym: "GRTH" EXACT [UniProtKB:Q9UHL0] xref: EMBL:AF155140 xref: EMBL:AY735301 xref: EMBL:AY735302 xref: EMBL:AY735303 xref: EMBL:AY735304 xref: EMBL:AY735305 xref: EMBL:AY735306 xref: EMBL:AY735307 xref: EMBL:AY735308 xref: EMBL:AY735309 xref: EMBL:AY735310 xref: EMBL:AY735311 xref: EMBL:AY735312 xref: EMBL:BC035388 xref: EMBL:BC050360 xref: HGNC:HGNC:18698 xref: UniGene:Hs.420263 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059144 ! DDX25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017548 name: DDX54_human def: "ATP-dependent RNA helicase DDX54 gene" [UniProtKB:Q8TDD1] xref: EMBL:AF478457 xref: EMBL:AY148094 xref: EMBL:BC005848 xref: HGNC:HGNC:20084 xref: UniGene:Hs.506861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057925 ! DDX54_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017549 name: DEAF1_human def: "Deformed epidermal autoregulatory factor 1 homolog gene" [UniProtKB:O75398] synonym: "SPN" EXACT [UniProtKB:O75398] synonym: "ZMYND5" EXACT [UniProtKB:O75398] xref: EMBL:AF007165 xref: EMBL:AF049459 xref: EMBL:AF049460 xref: EMBL:AF068893 xref: EMBL:AF068894 xref: EMBL:AF068895 xref: EMBL:AF068896 xref: EMBL:AF068897 xref: EMBL:BC053322 xref: HGNC:HGNC:14677 xref: UniGene:Hs.243994 xref: UniGene:Hs.448664 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054631 ! DEAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017550 name: DEF8_human def: "Differentially expressed in FDCP 8 homolog gene" [UniProtKB:Q6ZN54] xref: EMBL:AK000193 xref: EMBL:AK096485 xref: EMBL:AK131370 xref: EMBL:BC015482 xref: EMBL:BC105592 xref: EMBL:CH471184 xref: HGNC:HGNC:25969 xref: UniGene:Hs.62771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057011 ! DEFI8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017551 name: PDF_human def: "Peptide deformylase, mitochondrial precursor gene" [UniProtKB:Q9HBH1] synonym: "PDF1A" EXACT [UniProtKB:Q9HBH1] xref: EMBL:AF239156 xref: EMBL:AF322879 xref: EMBL:BC019912 xref: HGNC:HGNC:30012 xref: UniGene:Hs.693727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058785 ! DEFM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017552 name: EPB49_human def: "Dematin gene" [UniProtKB:Q08495] synonym: "DMT" EXACT [UniProtKB:Q08495] xref: EMBL:BC006318 xref: EMBL:BC017445 xref: EMBL:BC052805 xref: EMBL:BT007396 xref: EMBL:L19713 xref: EMBL:U28389 xref: HGNC:HGNC:3382 xref: UniGene:Hs.106124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055791 ! DEMA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017553 name: DEPDC1A_human def: "DEP domain-containing protein 1A gene" [UniProtKB:Q5TB30] synonym: "DEPDC1" EXACT [UniProtKB:Q5TB30] xref: EMBL:AB281187 xref: EMBL:AB281274 xref: EMBL:AJ278112 xref: EMBL:AK000490 xref: EMBL:AK022792 xref: EMBL:AL138789 xref: EMBL:BC003511 xref: EMBL:BC065304 xref: EMBL:CH471059 xref: HGNC:HGNC:22949 xref: UniGene:Hs.445098 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056604 ! DEP1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017554 name: DEPDC1B_human def: "DEP domain-containing protein 1B gene" [UniProtKB:Q8WUY9] synonym: "XTP8" EXACT [UniProtKB:Q8WUY9] xref: EMBL:AF303178 xref: EMBL:AF488828 xref: EMBL:AF490257 xref: EMBL:AK001166 xref: EMBL:AK002114 xref: EMBL:BC010904 xref: EMBL:BC019075 xref: HGNC:HGNC:24902 xref: UniGene:Hs.482233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057986 ! DEP1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017555 name: DEPDC4_human def: "DEP domain-containing protein 4 gene" [UniProtKB:Q8N2C3] xref: EMBL:AK090824 xref: EMBL:BC015117 xref: EMBL:BC100928 xref: EMBL:BC100929 xref: EMBL:BC100930 xref: HGNC:HGNC:22952 xref: UniGene:Hs.653118 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053762 ! A4FU15_HUMAN relationship: codes_for CCO:B0056283 ! Q3ZCN8_HUMAN relationship: codes_for CCO:B0057441 ! DEPD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017556 name: DEPDC5_human def: "DEP domain-containing protein 5 gene" [UniProtKB:O75140] synonym: "KIAA0645" EXACT [UniProtKB:O75140] xref: EMBL:AB014545 xref: EMBL:AC005004 xref: EMBL:AJ698950 xref: EMBL:AJ698951 xref: EMBL:AJ704764 xref: EMBL:AL022331 xref: EMBL:BC057797 xref: EMBL:BX640828 xref: EMBL:CR749304 xref: EMBL:Z82190 xref: EMBL:Z83856 xref: HGNC:HGNC:18423 xref: UniGene:Hs.435022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054208 ! B1AH81_HUMAN relationship: codes_for CCO:B0054604 ! DEPD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017557 name: DEPDC7_human def: "DEP domain-containing protein 7 gene" [UniProtKB:Q96QD5] xref: EMBL:AF447588 xref: EMBL:AJ245600 xref: EMBL:AL121926 xref: EMBL:BC030970 xref: HGNC:HGNC:29899 xref: UniGene:Hs.280990 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058352 ! DEPD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017558 name: DERL1_human def: "Derlin-1 gene" [UniProtKB:Q9BUN8] synonym: "DER1" EXACT [UniProtKB:Q9BUN8] synonym: "UNQ243/PRO276" EXACT [UniProtKB:Q9BUN8] xref: EMBL:AY358818 xref: EMBL:BC002457 xref: HGNC:HGNC:28454 xref: UniGene:Hs.241576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058523 ! DERL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017559 name: DERL2_human def: "Derlin-2 gene" [UniProtKB:Q9GZP9] synonym: "CGI-101" EXACT [UniProtKB:Q9GZP9] synonym: "DER2" EXACT [UniProtKB:Q9GZP9] synonym: "FLANA" EXACT [UniProtKB:Q9GZP9] synonym: "SBBI53" EXACT [UniProtKB:Q9GZP9] xref: EMBL:AF132289 xref: EMBL:AF151859 xref: EMBL:AF208065 xref: EMBL:AF242523 xref: EMBL:BC010890 xref: EMBL:CR457202 xref: HGNC:HGNC:17943 xref: UniGene:Hs.286131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058631 ! DERL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017560 name: DERL3_human def: "Derlin-3 gene" [UniProtKB:Q96Q80] synonym: "C22orf14" EXACT [UniProtKB:Q96Q80] synonym: "DER3" EXACT [UniProtKB:Q96Q80] synonym: "LLN2" EXACT [UniProtKB:Q96Q80] xref: EMBL:AB049213 xref: EMBL:AK125830 xref: EMBL:AP000350 xref: EMBL:BC057830 xref: EMBL:CR456372 xref: HGNC:HGNC:14236 xref: UniGene:Hs.593679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058351 ! DERL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017561 name: DERP6_human def: "Dermal papilla-derived protein 6 gene" [UniProtKB:Q8TE02] synonym: "C17orf81" EXACT [UniProtKB:Q8TE02] synonym: "HSPC002" EXACT [UniProtKB:Q8TE02] synonym: "MSTP071" EXACT [UniProtKB:Q8TE02] xref: EMBL:AB013910 xref: EMBL:AF070658 xref: EMBL:AF087868 xref: EMBL:AF163262 xref: EMBL:AL713741 xref: EMBL:BC002762 xref: HGNC:HGNC:30617 xref: UniGene:Hs.417029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057948 ! DERP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017562 name: DFFA_human def: "DNA fragmentation factor subunit alpha gene" [UniProtKB:O00273] synonym: "DFF1" EXACT [UniProtKB:O00273] synonym: "DFF45" EXACT [UniProtKB:O00273] synonym: "H13" EXACT [UniProtKB:O00273] xref: EMBL:AF087573 xref: EMBL:AF103799 xref: EMBL:BC000037 xref: EMBL:BC007112 xref: EMBL:BC007721 xref: EMBL:BT006980 xref: EMBL:U91985 xref: HGNC:HGNC:2772 xref: UniGene:Hs.484782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054307 ! DFFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017563 name: DGCR8_human def: "Protein DGCR8 gene" [UniProtKB:Q8WYQ5] synonym: "C22orf12" EXACT [UniProtKB:Q8WYQ5] synonym: "DGCRK6" EXACT [UniProtKB:Q8WYQ5] xref: EMBL:AB050770 xref: EMBL:AF165527 xref: EMBL:AK025539 xref: EMBL:AK025780 xref: EMBL:AY189282 xref: EMBL:BC009323 xref: EMBL:BC009984 xref: EMBL:BC078147 xref: EMBL:BX649187 xref: EMBL:CR456356 xref: HGNC:HGNC:2847 xref: UniGene:Hs.643452 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058048 ! DGCR8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017564 name: DGKA_human def: "Diacylglycerol kinase alpha gene" [UniProtKB:P23743] synonym: "DAGK" EXACT [UniProtKB:P23743] synonym: "DAGK1" EXACT [UniProtKB:P23743] xref: EMBL:AF064767 xref: EMBL:AF064768 xref: EMBL:AF064769 xref: EMBL:AF064771 xref: EMBL:BC023523 xref: EMBL:BC031870 xref: EMBL:X62535 xref: HGNC:HGNC:2849 xref: UniGene:Hs.524488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055162 ! DGKA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017565 name: DGKB_human def: "Diacylglycerol kinase beta gene" [UniProtKB:Q9Y6T7] synonym: "DAGK2" EXACT [UniProtKB:Q9Y6T7] synonym: "KIAA0718" EXACT [UniProtKB:Q9Y6T7] xref: EMBL:AB018261 xref: EMBL:AC005039 xref: EMBL:AC005248 xref: EMBL:AC006150 xref: EMBL:AC011229 xref: EMBL:AC073258 xref: EMBL:AC105459 xref: EMBL:AX032742 xref: EMBL:BC105005 xref: HGNC:HGNC:2850 xref: UniGene:Hs.567255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059417 ! DGKB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017566 name: DGKD_human def: "Diacylglycerol kinase delta gene" [UniProtKB:Q16760] synonym: "KIAA0145" EXACT [UniProtKB:Q16760] xref: EMBL:AB078966 xref: EMBL:BC006561 xref: EMBL:D63479 xref: EMBL:D73409 xref: HGNC:HGNC:2851 xref: UniGene:Hs.471675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056176 ! DGKD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017567 name: DGKE_human def: "Diacylglycerol kinase epsilon gene" [UniProtKB:P52429] synonym: "DAGK5" EXACT [UniProtKB:P52429] xref: EMBL:AF136745 xref: EMBL:U49379 xref: HGNC:HGNC:2852 xref: UniGene:Hs.591179 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055485 ! DGKE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017568 name: DGKG_human def: "Diacylglycerol kinase gamma gene" [UniProtKB:P49619] synonym: "DAGK3" EXACT [UniProtKB:P49619] xref: EMBL:AF020922 xref: EMBL:AF020923 xref: EMBL:AF020924 xref: EMBL:AF020925 xref: EMBL:AF020926 xref: EMBL:AF020927 xref: EMBL:AF020928 xref: EMBL:AF020929 xref: EMBL:AF020930 xref: EMBL:AF020931 xref: EMBL:AF020932 xref: EMBL:AF020933 xref: EMBL:AF020934 xref: EMBL:AF020935 xref: EMBL:AF020936 xref: EMBL:AF020937 xref: EMBL:AF020938 xref: EMBL:AF020939 xref: EMBL:AF020940 xref: EMBL:AF020941 xref: EMBL:AF020942 xref: EMBL:AF020943 xref: EMBL:AF020944 xref: EMBL:AF020945 xref: EMBL:BC089411 xref: EMBL:BC112363 xref: EMBL:D26135 xref: HGNC:HGNC:2853 xref: UniGene:Hs.592771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055425 ! DGKG_HUMAN relationship: codes_for CCO:B0056204 ! Q2M1H4_HUMAN relationship: codes_for CCO:B0056428 ! Q5FWG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017569 name: DGKH_human def: "Diacylglycerol kinase eta gene" [UniProtKB:Q86XP1] xref: EMBL:AB078967 xref: EMBL:AB078968 xref: EMBL:AK098302 xref: EMBL:AL136527 xref: EMBL:AL139328 xref: EMBL:AL157932 xref: EMBL:AL833883 xref: EMBL:BC043292 xref: HGNC:HGNC:2854 xref: UniGene:Hs.659437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057292 ! DGKH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017570 name: DGKI_human def: "Diacylglycerol kinase iota gene" [UniProtKB:O75912] xref: EMBL:AF061936 xref: EMBL:AF219907 xref: EMBL:AF219908 xref: EMBL:AF219909 xref: EMBL:AF219910 xref: EMBL:AF219911 xref: EMBL:AF219912 xref: EMBL:AF219913 xref: EMBL:AF219914 xref: EMBL:AF219915 xref: EMBL:AF219916 xref: EMBL:AF219917 xref: EMBL:AF219918 xref: EMBL:AF219919 xref: EMBL:AF219920 xref: EMBL:AF219921 xref: EMBL:AF219922 xref: EMBL:AF219923 xref: EMBL:AF219924 xref: EMBL:AF219925 xref: EMBL:AF219926 xref: EMBL:AF219927 xref: EMBL:AF219928 xref: EMBL:AF219929 xref: EMBL:AF219930 xref: EMBL:AF219931 xref: EMBL:AF219932 xref: EMBL:AF219933 xref: EMBL:AF219934 xref: EMBL:AF219935 xref: EMBL:AF219936 xref: EMBL:AF219937 xref: EMBL:AF219938 xref: EMBL:AF219939 xref: HGNC:HGNC:2855 xref: UniGene:Hs.242947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054677 ! DGKI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017571 name: DGKK_human def: "Diacylglycerol kinase kappa gene" [UniProtKB:Q5KSL6] xref: EMBL:AB183864 xref: HGNC:HGNC:32395 xref: UniGene:Hs.631770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056515 ! DGKK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017572 name: DGKQ_human def: "Diacylglycerol kinase theta gene" [UniProtKB:P52824] synonym: "DAGK4" EXACT [UniProtKB:P52824] xref: EMBL:L38707 xref: HGNC:HGNC:2856 xref: UniGene:Hs.584858 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055503 ! DGKQ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017573 name: DGKZ_human def: "Diacylglycerol kinase zeta gene" [UniProtKB:Q13574] synonym: "DAGK6" EXACT [UniProtKB:Q13574] xref: EMBL:AC116021 xref: EMBL:BC008018 xref: EMBL:BC041770 xref: EMBL:U51477 xref: EMBL:U94905 xref: HGNC:HGNC:2857 xref: UniGene:Hs.502461 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055932 ! DGKZ_HUMAN relationship: codes_for CCO:B0057186 ! Q7Z5X8_HUMAN relationship: codes_for CCO:B0057350 ! Q8IVW9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017574 name: DHCR7_human def: "7-dehydrocholesterol reductase gene" [UniProtKB:Q9UBM7] synonym: "D7SR" EXACT [UniProtKB:Q9UBM7] xref: EMBL:AF034544 xref: EMBL:AF062481 xref: EMBL:AF067127 xref: EMBL:AF096305 xref: EMBL:AF110060 xref: EMBL:BC000054 xref: HGNC:HGNC:2860 xref: UniGene:Hs.503134 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059078 ! DHCR7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017575 name: GLUD1_human def: "Glutamate dehydrogenase 1, mitochondrial precursor gene" [UniProtKB:P00367] synonym: "GLUD" EXACT [UniProtKB:P00367] xref: EMBL:AL136982 xref: EMBL:BC040132 xref: EMBL:BC112946 xref: EMBL:J03248 xref: EMBL:M20867 xref: EMBL:M37154 xref: EMBL:X07674 xref: EMBL:X07769 xref: EMBL:X66300 xref: EMBL:X66301 xref: EMBL:X66302 xref: EMBL:X66303 xref: EMBL:X66304 xref: EMBL:X66305 xref: EMBL:X66306 xref: EMBL:X66307 xref: EMBL:X66308 xref: EMBL:X66309 xref: EMBL:X66311 xref: EMBL:X66312 xref: EMBL:X67491 xref: HGNC:HGNC:4335 xref: UniGene:Hs.500409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054824 ! DHE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017576 name: DHPS_human def: "Deoxyhypusine synthase gene" [UniProtKB:P49366] synonym: "DS" EXACT [UniProtKB:P49366] xref: EMBL:AJ001701 xref: EMBL:AJ001702 xref: EMBL:AJ001703 xref: EMBL:AJ001704 xref: EMBL:BC000333 xref: EMBL:BC014016 xref: EMBL:L39068 xref: EMBL:U26266 xref: EMBL:U32178 xref: EMBL:U40579 xref: EMBL:U79262 xref: HGNC:HGNC:2869 xref: UniGene:Hs.79064 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055423 ! DHYS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017577 name: DIAPH2_human def: "Protein diaphanous homolog 2 gene" [UniProtKB:O60879] synonym: "DIA" EXACT [UniProtKB:O60879] xref: EMBL:AL031053 xref: EMBL:AL139809 xref: EMBL:AL161624 xref: EMBL:AL391821 xref: EMBL:AL592157 xref: EMBL:AL606530 xref: EMBL:AL669876 xref: EMBL:Y15908 xref: EMBL:Y15909 xref: EMBL:Z86061 xref: HGNC:HGNC:2877 xref: UniGene:Hs.696382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054584 ! DIAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017578 name: DIXDC1_human def: "Dixin gene" [UniProtKB:Q155Q3] synonym: "CCD1" EXACT [UniProtKB:Q155Q3] synonym: "KIAA1735" EXACT [UniProtKB:Q155Q3] xref: EMBL:AB051522 xref: EMBL:AK055899 xref: EMBL:BC033034 xref: EMBL:BC035509 xref: EMBL:BC041626 xref: EMBL:BC064479 xref: EMBL:BC128600 xref: EMBL:DQ642016 xref: HGNC:HGNC:23695 xref: UniGene:Hs.655626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056077 ! DIXC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017579 name: DKK1_human def: "Dickkopf-related protein 1 precursor gene" [UniProtKB:O94907] synonym: "UNQ492/PRO1008" EXACT [UniProtKB:O94907] xref: EMBL:AB020315 xref: EMBL:AF127563 xref: EMBL:AF177394 xref: EMBL:AF261157 xref: EMBL:AF261158 xref: EMBL:AY359005 xref: EMBL:BC001539 xref: HGNC:HGNC:2891 xref: UniGene:Hs.40499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054709 ! DKK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017580 name: DKK2_human def: "Dickkopf-related protein 2 precursor gene" [UniProtKB:Q9UBU2] synonym: "UNQ682/PRO1316" EXACT [UniProtKB:Q9UBU2] xref: EMBL:AB033208 xref: EMBL:AB033941 xref: EMBL:AB035181 xref: EMBL:AF177395 xref: EMBL:AY358414 xref: EMBL:BC075077 xref: EMBL:BC075078 xref: EMBL:BC126328 xref: EMBL:BC126330 xref: EMBL:CH471057 xref: HGNC:HGNC:2892 xref: UniGene:Hs.211869 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058710 ! Q9H3R7_HUMAN relationship: codes_for CCO:B0059085 ! DKK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017581 name: DKK3_human def: "Dickkopf-related protein 3 precursor gene" [UniProtKB:Q9UBP4] synonym: "REIC" EXACT [UniProtKB:Q9UBP4] synonym: "UNQ258/PRO295" EXACT [UniProtKB:Q9UBP4] xref: EMBL:AB033421 xref: EMBL:AB034203 xref: EMBL:AB035182 xref: EMBL:AB057591 xref: EMBL:AB057804 xref: EMBL:AF177396 xref: EMBL:AY358378 xref: EMBL:BC007660 xref: HGNC:HGNC:2893 xref: UniGene:Hs.292156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059080 ! DKK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017582 name: DKK4_human def: "Dickkopf-related protein 4 precursor gene" [UniProtKB:Q9UBT3] xref: EMBL:AB017788 xref: EMBL:AB018005 xref: EMBL:AF177397 xref: EMBL:BC107046 xref: EMBL:BC107047 xref: HGNC:HGNC:2894 xref: UniGene:Hs.159311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059084 ! DKK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017583 name: DLL3_human def: "Delta-like protein 3 precursor gene" [UniProtKB:Q9NYJ7] xref: EMBL:AF241367 xref: EMBL:AF241368 xref: EMBL:AF241369 xref: EMBL:AF241370 xref: EMBL:AF241371 xref: EMBL:AF241372 xref: EMBL:AF241373 xref: EMBL:BC000218 xref: HGNC:HGNC:2909 xref: UniGene:Hs.127792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024312 ! DLL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017584 name: DLX1_human def: "Homeobox protein DLX-1 gene" [UniProtKB:P56177] xref: EMBL:AY257976 xref: EMBL:BC036189 xref: HGNC:HGNC:2914 xref: UniGene:Hs.407015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055539 ! DLX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017585 name: DMBX1_human def: "Diencephalon/mesencephalon homeobox protein 1 gene" [UniProtKB:Q8NFW5] synonym: "MBX" EXACT [UniProtKB:Q8NFW5] synonym: "OTX3" EXACT [UniProtKB:Q8NFW5] synonym: "PAXB" EXACT [UniProtKB:Q8NFW5] xref: EMBL:AB037699 xref: EMBL:AF398527 xref: EMBL:AF398528 xref: EMBL:AL137797 xref: EMBL:CH471059 xref: HGNC:HGNC:19026 xref: UniGene:Hs.375623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057609 ! DMBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017586 name: DMPK_human def: "Myotonin-protein kinase gene" [UniProtKB:Q09013] synonym: "MDPK" EXACT [UniProtKB:Q09013] xref: EMBL:L00727 xref: EMBL:L08835 xref: EMBL:L19266 xref: EMBL:L19268 xref: EMBL:M87312 xref: EMBL:M94203 xref: EMBL:S72883 xref: EMBL:U46546 xref: HGNC:HGNC:2933 xref: UniGene:Hs.631596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055804 ! DMPK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017587 name: DMRT1_human def: "Doublesex- and mab-3-related transcription factor 1 gene" [UniProtKB:Q9Y5R6] synonym: "DMT1" EXACT [UniProtKB:Q9Y5R6] xref: EMBL:AF130728 xref: EMBL:AJ276801 xref: EMBL:AL136365 xref: EMBL:AL162131 xref: EMBL:AY442915 xref: EMBL:BC040847 xref: HGNC:HGNC:2934 xref: UniGene:Hs.98586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056943 ! Q6T1H8_HUMAN relationship: codes_for CCO:B0059384 ! DMRT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017588 name: DMRT2_human def: "Doublesex- and mab-3-related transcription factor 2 gene" [UniProtKB:Q9Y5R5] synonym: "DSXL2" EXACT [UniProtKB:Q9Y5R5] xref: EMBL:AF130729 xref: EMBL:AF284223 xref: EMBL:AF284224 xref: EMBL:AF284225 xref: EMBL:Y19052 xref: HGNC:HGNC:2935 xref: UniGene:Hs.59506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058870 ! Q9NQR6_HUMAN relationship: codes_for CCO:B0059383 ! DMRT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017589 name: DMRT3_human def: "Doublesex- and mab-3-related transcription factor 3 gene" [UniProtKB:Q9NQL9] synonym: "DMRTA3" EXACT [UniProtKB:Q9NQL9] xref: EMBL:AF193873 xref: EMBL:AJ301581 xref: EMBL:AL136365 xref: EMBL:BC113584 xref: EMBL:BC117245 xref: HGNC:HGNC:13909 xref: UniGene:Hs.189174 xref: UniGene:Hs.672740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058868 ! DMRT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017590 name: DMRTA1_human def: "Doublesex- and mab-3-related transcription factor A1 gene" [UniProtKB:Q5VZB9] synonym: "DMO" EXACT [UniProtKB:Q5VZB9] xref: EMBL:AJ290954 xref: EMBL:AK096011 xref: EMBL:AL161730 xref: HGNC:HGNC:13826 xref: UniGene:Hs.371976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056674 ! DMRTA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017591 name: DMRTB1_human def: "Doublesex- and mab-3-related transcription factor B1 gene" [UniProtKB:Q96MA1] xref: EMBL:AJ291671 xref: EMBL:AK057273 xref: EMBL:AL365445 xref: EMBL:CH471059 xref: HGNC:HGNC:13913 xref: UniGene:Hs.131654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058283 ! DMRTB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017592 name: DMRTC1_human def: "Doublesex- and mab-3-related transcription factor C1 gene" [UniProtKB:Q5HYR2] xref: EMBL:AJ291670 xref: EMBL:BC029799 xref: EMBL:BC047596 xref: EMBL:BX293538 xref: HGNC:HGNC:13910 xref: UniGene:Hs.558685 xref: UniGene:Hs.658177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056445 ! DMRTC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017593 name: DMRTC2_human def: "Doublesex- and mab-3-related transcription factor C2 gene" [UniProtKB:Q8IXT2] xref: EMBL:AJ291669 xref: EMBL:AK057404 xref: EMBL:BC029202 xref: EMBL:BC039266 xref: HGNC:HGNC:13911 xref: UniGene:Hs.350507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057381 ! DMRTD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017594 name: DMRTA2_human def: "Doublesex- and mab-3-related transcription factor A2 gene" [UniProtKB:Q96SC8] synonym: "DMRT5" EXACT [UniProtKB:Q96SC8] xref: EMBL:AJ301580 xref: EMBL:AL049637 xref: HGNC:HGNC:13908 xref: UniGene:Hs.334481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058390 ! DMTA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017595 name: DNER_human def: "Delta and Notch-like epidermal growth factor-related receptor precursor gene" [UniProtKB:Q8NFT8] synonym: "BET" EXACT [UniProtKB:Q8NFT8] synonym: "UNQ262/PRO299" EXACT [UniProtKB:Q8NFT8] xref: EMBL:AC007559 xref: EMBL:AC007748 xref: EMBL:AC008273 xref: EMBL:AC093384 xref: EMBL:AF442487 xref: EMBL:AL137311 xref: EMBL:AY358891 xref: EMBL:BC024766 xref: EMBL:BC035009 xref: EMBL:CH471063 xref: HGNC:HGNC:24456 xref: UniGene:Hs.234074 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057608 ! DNER_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017596 name: DNAJC1_human def: "DnaJ homolog subfamily C member 1 gene" [UniProtKB:Q96KC8] synonym: "HTJ1" EXACT [UniProtKB:Q96KC8] xref: EMBL:AK026062 xref: EMBL:AK027263 xref: EMBL:AL359697 xref: EMBL:AL445431 xref: EMBL:AY225122 xref: EMBL:BC110894 xref: HGNC:HGNC:20090 xref: UniGene:Hs.499000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058258 ! DNJC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017597 name: DNM1L_human def: "Dynamin-1-like protein gene" [UniProtKB:O00429] synonym: "DLP1" EXACT [UniProtKB:O00429] synonym: "DRP1" EXACT [UniProtKB:O00429] xref: EMBL:AB006965 xref: EMBL:AF000430 xref: EMBL:AF061795 xref: EMBL:AF151685 xref: EMBL:BC000136 xref: EMBL:BC024590 xref: HGNC:HGNC:2973 xref: UniGene:Hs.556296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054320 ! DNM1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017598 name: DNMBP_human def: "Dynamin-binding protein gene" [UniProtKB:Q6XZF7] synonym: "KIAA1010" EXACT [UniProtKB:Q6XZF7] xref: EMBL:AB023227 xref: EMBL:AL392107 xref: EMBL:AY196211 xref: EMBL:BC041628 xref: HGNC:HGNC:30373 xref: UniGene:Hs.500771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054036 ! A8MU01_HUMAN relationship: codes_for CCO:B0056974 ! DNMBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017599 name: DNASE1L3_human def: "Deoxyribonuclease gamma precursor gene" [UniProtKB:Q13609] synonym: "DHP2" EXACT [UniProtKB:Q13609] synonym: "DNAS1L3" EXACT [UniProtKB:Q13609] xref: EMBL:AF047354 xref: EMBL:BC015831 xref: EMBL:U56814 xref: EMBL:U75744 xref: HGNC:HGNC:2959 xref: UniGene:Hs.476453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055935 ! DNSL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017600 name: DOCK7_human def: "Dedicator of cytokinesis protein 7 gene" [UniProtKB:Q96N67] synonym: "KIAA1771" EXACT [UniProtKB:Q96N67] xref: EMBL:AB051558 xref: EMBL:AC096946 xref: EMBL:AC103923 xref: EMBL:AK055493 xref: EMBL:AK055905 xref: EMBL:AK125049 xref: EMBL:AL138847 xref: EMBL:AL451044 xref: EMBL:BC016392 xref: EMBL:DQ118679 xref: EMBL:DQ118680 xref: EMBL:DQ309763 xref: EMBL:DQ341187 xref: HGNC:HGNC:19190 xref: UniGene:Hs.538059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058300 ! DOCK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017601 name: DOK1_human def: "Docking protein 1 gene" [UniProtKB:Q99704] xref: EMBL:AC005033 xref: EMBL:AF035299 xref: EMBL:AF180527 xref: EMBL:BC114440 xref: EMBL:U70987 xref: HGNC:HGNC:2990 xref: UniGene:Hs.103854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058443 ! DOK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017602 name: DOK2_human def: "Docking protein 2 gene" [UniProtKB:O60496] xref: EMBL:AF034970 xref: EMBL:BC032623 xref: HGNC:HGNC:2991 xref: UniGene:Hs.71215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054562 ! DOK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017603 name: DOK3_human def: "Docking protein 3 gene" [UniProtKB:Q7L591] xref: EMBL:AK026223 xref: EMBL:AK097258 xref: EMBL:BC004564 xref: EMBL:BC004867 xref: HGNC:HGNC:24583 xref: UniGene:Hs.153343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057120 ! DOK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017604 name: DOK4_human def: "Docking protein 4 gene" [UniProtKB:Q8TEW6] xref: EMBL:AC004382 xref: EMBL:AF466369 xref: EMBL:AK001350 xref: EMBL:BC001540 xref: EMBL:BC003541 xref: HGNC:HGNC:19868 xref: UniGene:Hs.279832 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057957 ! DOK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017605 name: DBH_human def: "Dopamine beta-hydroxylase gene" [UniProtKB:P09172] xref: EMBL:AL365494 xref: EMBL:BC017174 xref: EMBL:X13255 xref: EMBL:X13256 xref: EMBL:Y00096 xref: HGNC:HGNC:2689 xref: UniGene:Hs.591890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054941 ! DOPO_HUMAN relationship: codes_for CCO:B0056567 ! Q5T382_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017606 name: DPF1_human def: "Zinc finger protein neuro-d4 gene" [UniProtKB:Q92782] synonym: "NEUD4" EXACT [UniProtKB:Q92782] xref: EMBL:U43843 xref: HGNC:HGNC:20225 xref: UniGene:Hs.631576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058092 ! DPF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017607 name: POLG2_human def: "DNA polymerase subunit gamma-2, mitochondrial precursor gene" [UniProtKB:Q9UHN1] synonym: "MTPOLB" EXACT [UniProtKB:Q9UHN1] xref: EMBL:AF142992 xref: EMBL:AF177201 xref: EMBL:AF184344 xref: EMBL:BC000913 xref: EMBL:BC009194 xref: EMBL:U94703 xref: HGNC:HGNC:9180 xref: UniGene:Hs.437009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059145 ! DPOG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017608 name: POLB_human def: "DNA polymerase beta gene" [UniProtKB:P06746] xref: EMBL:AF491812 xref: EMBL:BC100288 xref: EMBL:BC106909 xref: EMBL:CR536503 xref: EMBL:CR541802 xref: EMBL:D29013 xref: EMBL:J04201 xref: EMBL:L11607 xref: EMBL:M13140 xref: EMBL:U10516 xref: EMBL:U10517 xref: EMBL:U10519 xref: EMBL:U10520 xref: EMBL:U10521 xref: EMBL:U10522 xref: EMBL:U10523 xref: EMBL:U10524 xref: EMBL:U10525 xref: EMBL:U10526 xref: HGNC:HGNC:9174 xref: UniGene:Hs.654484 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054905 ! DPOLB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017609 name: POLL_human def: "DNA polymerase lambda gene" [UniProtKB:Q9UGP5] xref: EMBL:AF161019 xref: EMBL:AF218027 xref: EMBL:AF283478 xref: EMBL:AF525924 xref: EMBL:AJ131890 xref: EMBL:AK021600 xref: EMBL:AK022476 xref: EMBL:AL627424 xref: EMBL:BC003548 xref: EMBL:BC068529 xref: EMBL:CH471066 xref: HGNC:HGNC:9184 xref: UniGene:Hs.523230 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056457 ! Q5JQP3_HUMAN relationship: codes_for CCO:B0056458 ! Q5JQP8_HUMAN relationship: codes_for CCO:B0058515 ! Q9BTN8_HUMAN relationship: codes_for CCO:B0058762 ! Q9HAJ3_HUMAN relationship: codes_for CCO:B0058787 ! Q9HBN3_HUMAN relationship: codes_for CCO:B0059125 ! DPOLL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017610 name: POLM_human def: "DNA polymerase mu gene" [UniProtKB:Q9NP87] xref: EMBL:AF176097 xref: EMBL:AJ131891 xref: EMBL:AY899911 xref: EMBL:BC049202 xref: EMBL:BC062590 xref: EMBL:CH471128 xref: HGNC:HGNC:9185 xref: UniGene:Hs.596982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056891 ! Q6P5X8_HUMAN relationship: codes_for CCO:B0057279 ! Q86WQ9_HUMAN relationship: codes_for CCO:B0058840 ! DPOLM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017611 name: POLN_human def: "DNA polymerase nu gene" [UniProtKB:Q7Z5Q5] xref: EMBL:AK131239 xref: EMBL:AY136549 xref: EMBL:DQ060036 xref: HGNC:HGNC:18870 xref: UniGene:Hs.368454 xref: UniGene:Hs.706220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057185 ! DPOLN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017612 name: REV3L_human def: "DNA polymerase zeta catalytic subunit gene" [UniProtKB:O60673] synonym: "POLZ" EXACT [UniProtKB:O60673] synonym: "REV3" EXACT [UniProtKB:O60673] xref: EMBL:AF035537 xref: EMBL:AF058701 xref: EMBL:AF071798 xref: EMBL:AF078695 xref: EMBL:AF157476 xref: EMBL:AF179428 xref: EMBL:AF179429 xref: EMBL:AL080317 xref: EMBL:AL136310 xref: EMBL:AL512325 xref: EMBL:AY684169 xref: HGNC:HGNC:9968 xref: UniGene:Hs.232021 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053891 ! A6NL09_HUMAN relationship: codes_for CCO:B0054574 ! DPOLZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017613 name: DPRX_human def: "Divergent paired-related homeobox gene" [UniProtKB:A6NFQ7] xref: EMBL:AC011487 xref: HGNC:HGNC:32166 xref: UniGene:Hs.579941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053823 ! DPRX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017614 name: DPYSL2_human def: "Dihydropyrimidinase-related protein 2 gene" [UniProtKB:Q16555] synonym: "CRMP2" EXACT [UniProtKB:Q16555] xref: EMBL:AB020777 xref: EMBL:BC056408 xref: EMBL:BC067109 xref: EMBL:D78013 xref: EMBL:U17279 xref: EMBL:U97105 xref: HGNC:HGNC:3014 xref: UniGene:Hs.173381 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056150 ! DPYL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017615 name: DPYSL3_human def: "Dihydropyrimidinase-related protein 3 gene" [UniProtKB:Q14195] synonym: "CRMP4" EXACT [UniProtKB:Q14195] synonym: "DRP3" EXACT [UniProtKB:Q14195] synonym: "ULIP" EXACT [UniProtKB:Q14195] xref: EMBL:D78014 xref: EMBL:Y07818 xref: HGNC:HGNC:3015 xref: UniGene:Hs.519659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055970 ! DPYL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017616 name: DPYSL5_human def: "Dihydropyrimidinase-related protein 5 gene" [UniProtKB:Q9BPU6] synonym: "CRMP5" EXACT [UniProtKB:Q9BPU6] synonym: "ULIP6" EXACT [UniProtKB:Q9BPU6] xref: EMBL:AF157634 xref: EMBL:AF264015 xref: EMBL:AJ251275 xref: EMBL:AL713706 xref: EMBL:BC002874 xref: EMBL:BT006871 xref: HGNC:HGNC:20637 xref: UniGene:Hs.299315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058468 ! DPYL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017617 name: DRD1_human def: "D(1A) dopamine receptor gene" [UniProtKB:P21728] xref: EMBL:AB065677 xref: EMBL:AF498961 xref: EMBL:BC074978 xref: EMBL:BC074979 xref: EMBL:BC096837 xref: EMBL:S58541 xref: EMBL:X55758 xref: EMBL:X55760 xref: EMBL:X58987 xref: HGNC:HGNC:3020 xref: UniGene:Hs.2624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055136 ! DRD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017618 name: DRD2_human def: "D(2) dopamine receptor gene" [UniProtKB:P14416] xref: EMBL:AB065860 xref: EMBL:AF050737 xref: EMBL:AF176812 xref: EMBL:BC021195 xref: EMBL:M29066 xref: EMBL:M30625 xref: EMBL:S58577 xref: EMBL:S58584 xref: EMBL:S58586 xref: EMBL:S58588 xref: EMBL:S58589 xref: EMBL:S62137 xref: EMBL:S69899 xref: EMBL:X51362 xref: EMBL:X51645 xref: EMBL:X51646 xref: HGNC:HGNC:3023 xref: UniGene:Hs.73893 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055024 ! DRD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017619 name: DRD3_human def: "D(3) dopamine receptor gene" [UniProtKB:P35462] xref: EMBL:BC095510 xref: EMBL:L20469 xref: EMBL:L35902 xref: EMBL:L35903 xref: EMBL:U32499 xref: HGNC:HGNC:3024 xref: UniGene:Hs.121478 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055293 ! DRD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017620 name: DRD4_human def: "D(4) dopamine receptor gene" [UniProtKB:P21917] xref: EMBL:AF395229 xref: EMBL:AF395234 xref: EMBL:AF395241 xref: EMBL:AF395261 xref: EMBL:AF395264 xref: EMBL:AY151038 xref: EMBL:L12397 xref: EMBL:L12398 xref: HGNC:HGNC:3025 xref: UniGene:Hs.99922 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055139 ! DRD4_HUMAN relationship: codes_for CCO:B0057399 ! Q8IZB1_HUMAN relationship: codes_for CCO:B0057970 ! Q8WTR3_HUMAN relationship: codes_for CCO:B0058031 ! Q8WXL5_HUMAN relationship: codes_for CCO:B0058032 ! Q8WXL8_HUMAN relationship: codes_for CCO:B0058033 ! Q8WXN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017621 name: DRD5_human def: "D(1B) dopamine receptor gene" [UniProtKB:P21918] synonym: "DRD1B" EXACT [UniProtKB:P21918] synonym: "DRD1L2" EXACT [UniProtKB:P21918] xref: EMBL:AY136750 xref: EMBL:BC009748 xref: EMBL:M67439 xref: EMBL:X58454 xref: HGNC:HGNC:3026 xref: UniGene:Hs.380681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055140 ! DRD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017622 name: DRG2_human def: "Developmentally-regulated GTP-binding protein 2 gene" [UniProtKB:P55039] xref: EMBL:BC000493 xref: EMBL:X80754 xref: HGNC:HGNC:3030 xref: UniGene:Hs.78582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055522 ! DRG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017623 name: DRGX_human def: "Dorsal root ganglia homeobox protein gene" [UniProtKB:A6NNA5] synonym: "PRRXL1" EXACT [UniProtKB:A6NNA5] xref: EMBL:AC027674 xref: EMBL:CH471187 xref: HGNC:HGNC:21536 xref: UniGene:Hs.534530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053913 ! DRGX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017624 name: ADAR_human def: "Double-stranded RNA-specific adenosine deaminase gene" [UniProtKB:P55265] synonym: "ADAR1" EXACT [UniProtKB:P55265] synonym: "DSRAD" EXACT [UniProtKB:P55265] synonym: "G1P1" EXACT [UniProtKB:P55265] synonym: "IFI4" EXACT [UniProtKB:P55265] xref: EMBL:BC038227 xref: EMBL:BX538232 xref: EMBL:BX640741 xref: EMBL:U10439 xref: EMBL:U18121 xref: EMBL:U75489 xref: EMBL:U75490 xref: EMBL:U75491 xref: EMBL:U75492 xref: EMBL:U75493 xref: EMBL:U75494 xref: EMBL:U75495 xref: EMBL:U75496 xref: EMBL:U75497 xref: EMBL:U75498 xref: EMBL:U75499 xref: EMBL:U75500 xref: EMBL:U75501 xref: EMBL:U75502 xref: EMBL:U75503 xref: EMBL:X79448 xref: EMBL:X79449 xref: EMBL:X98559 xref: HGNC:HGNC:225 xref: UniGene:Hs.12341 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055532 ! DSRAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017625 name: DTX1_human def: "Protein deltex-1 gene" [UniProtKB:Q86Y01] xref: EMBL:AF053700 xref: EMBL:BC005816 xref: EMBL:BC048216 xref: HGNC:HGNC:3060 xref: UniGene:Hs.372152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057298 ! DTX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017626 name: DTX2_human def: "Protein deltex-2 gene" [UniProtKB:Q86UW9] synonym: "KIAA1528" EXACT [UniProtKB:Q86UW9] synonym: "RNF58" EXACT [UniProtKB:Q86UW9] xref: EMBL:AB040961 xref: EMBL:AC005522 xref: EMBL:AC007078 xref: EMBL:AK023924 xref: EMBL:BC008856 xref: EMBL:BC018555 xref: EMBL:BC026059 xref: HGNC:HGNC:15973 xref: UniGene:Hs.187058 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057257 ! DTX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017627 name: DTX3_human def: "Protein deltex-3 gene" [UniProtKB:Q8N9I9] synonym: "RNF154" EXACT [UniProtKB:Q8N9I9] xref: EMBL:AK092085 xref: EMBL:AK094385 xref: EMBL:AL831941 xref: HGNC:HGNC:24457 xref: UniGene:Hs.32374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057537 ! DTX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017628 name: DTX4_human def: "Protein deltex-4 gene" [UniProtKB:Q9Y2E6] synonym: "KIAA0937" EXACT [UniProtKB:Q9Y2E6] synonym: "RNF155" EXACT [UniProtKB:Q9Y2E6] xref: EMBL:AB023154 xref: EMBL:BC119011 xref: EMBL:BC122861 xref: HGNC:HGNC:29151 xref: UniGene:Hs.523696 xref: UniGene:Hs.700662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059301 ! DTX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017629 name: DARC_human def: "Duffy antigen/chemokine receptor gene" [UniProtKB:Q16570] synonym: "FY" EXACT [UniProtKB:Q16570] synonym: "GPD" EXACT [UniProtKB:Q16570] xref: EMBL:AF030521 xref: EMBL:AF055992 xref: EMBL:AF100634 xref: EMBL:AL035403 xref: EMBL:BC017817 xref: EMBL:S76830 xref: EMBL:U01839 xref: EMBL:X85785 xref: HGNC:HGNC:4035 xref: UniGene:Hs.153381 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056153 ! DUFFY_HUMAN relationship: codes_for CCO:B0056505 ! Q5JY94_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017630 name: DUOX1_human def: "Dual oxidase 1 precursor gene" [UniProtKB:Q9NRD9] synonym: "DUOX" EXACT [UniProtKB:Q9NRD9] synonym: "LNOX1" EXACT [UniProtKB:Q9NRD9] synonym: "THOX1" EXACT [UniProtKB:Q9NRD9] xref: EMBL:AC051619 xref: EMBL:AF213465 xref: EMBL:AF230495 xref: EMBL:AK128591 xref: EMBL:AK172859 xref: EMBL:BC114628 xref: HGNC:HGNC:3062 xref: UniGene:Hs.272813 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058897 ! DUOX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017631 name: DUOX2_human def: "Dual oxidase 2 precursor gene" [UniProtKB:Q9NRD8] synonym: "LNOX2" EXACT [UniProtKB:Q9NRD8] synonym: "THOX2" EXACT [UniProtKB:Q9NRD8] xref: EMBL:AC091117 xref: EMBL:AF181972 xref: EMBL:AF230496 xref: EMBL:AF267981 xref: HGNC:HGNC:13273 xref: UniGene:Hs.71377 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058896 ! DUOX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017632 name: DUSP10_human def: "Dual specificity protein phosphatase 10 gene" [UniProtKB:Q9Y6W6] synonym: "MKP5" EXACT [UniProtKB:Q9Y6W6] xref: EMBL:AB026436 xref: EMBL:AF179212 xref: EMBL:AL590966 xref: EMBL:BC031405 xref: EMBL:BC063826 xref: HGNC:HGNC:3065 xref: UniGene:Hs.497822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059419 ! DUS10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017633 name: DUSP19_human def: "Dual specificity protein phosphatase 19 gene" [UniProtKB:Q8WTR2] synonym: "DUSP17" EXACT [UniProtKB:Q8WTR2] synonym: "SKRP1" EXACT [UniProtKB:Q8WTR2] xref: EMBL:AB038770 xref: EMBL:AB063186 xref: EMBL:AB063187 xref: EMBL:AC064871 xref: EMBL:AF486808 xref: EMBL:BC035000 xref: EMBL:BC093958 xref: EMBL:BC112005 xref: HGNC:HGNC:18894 xref: UniGene:Hs.132237 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057969 ! DUS19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017634 name: DUSP21_human def: "Dual specificity protein phosphatase 21 gene" [UniProtKB:Q9H596] synonym: "LMWDSP21" EXACT [UniProtKB:Q9H596] xref: EMBL:AF533018 xref: EMBL:AL133545 xref: EMBL:AY156515 xref: EMBL:BC119755 xref: EMBL:BC119756 xref: EMBL:CR457159 xref: HGNC:HGNC:20476 xref: UniGene:Hs.534478 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058724 ! DUS21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017635 name: DUSP22_human def: "Dual specificity protein phosphatase 22 gene" [UniProtKB:Q9NRW4] synonym: "JSP1" EXACT [UniProtKB:Q9NRW4] synonym: "MKPX" EXACT [UniProtKB:Q9NRW4] xref: EMBL:AB208997 xref: EMBL:AF165519 xref: EMBL:AF424702 xref: EMBL:AL365272 xref: EMBL:AY249859 xref: EMBL:BC016844 xref: EMBL:BC022847 xref: HGNC:HGNC:16077 xref: UniGene:Hs.29106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058906 ! DUS22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017636 name: DUSP9_human def: "Dual specificity protein phosphatase 9 gene" [UniProtKB:Q99956] synonym: "MKP4" EXACT [UniProtKB:Q99956] xref: EMBL:U52111 xref: EMBL:Y08302 xref: HGNC:HGNC:3076 xref: UniGene:Hs.144879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058464 ! DUS9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017637 name: DUT_human def: "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor gene" [UniProtKB:P33316] xref: EMBL:AB049113 xref: EMBL:AF018429 xref: EMBL:AF018430 xref: EMBL:AF018431 xref: EMBL:AF018432 xref: EMBL:AY935242 xref: EMBL:BC033645 xref: EMBL:BC070339 xref: EMBL:BC110377 xref: EMBL:CH471082 xref: EMBL:L11877 xref: EMBL:M89913 xref: EMBL:U31930 xref: EMBL:U62891 xref: EMBL:U90223 xref: EMBL:U90224 xref: HGNC:HGNC:3078 xref: UniGene:Hs.527980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055266 ! DUT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017638 name: DUX1_human def: "Double homeobox protein 1 gene" [UniProtKB:O43812] xref: EMBL:AJ001481 xref: HGNC:HGNC:3079 xref: UniGene:Hs.274469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054521 ! DUX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017639 name: DUX2_human def: "Putative double homeobox protein 2 gene" [UniProtKB:O75505] xref: EMBL:AF068744 xref: HGNC:HGNC:3080 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054645 ! DUX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017640 name: DUX3_human def: "Putative double homeobox protein 3 gene" [UniProtKB:Q96PT4] xref: EMBL:AF133130 xref: HGNC:HGNC:3081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058344 ! DUX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017641 name: DUX4_human def: "Double homeobox protein 4 gene" [UniProtKB:Q9UBX2] synonym: "DUX10" EXACT [UniProtKB:Q9UBX2] xref: EMBL:AF117653 xref: EMBL:AY044051 xref: EMBL:D38024 xref: HGNC:HGNC:3082 xref: UniGene:Hs.553518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055980 ! Q14333_HUMAN relationship: codes_for CCO:B0059090 ! DUX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017642 name: DUX5_human def: "Double homeobox protein 5 gene" [UniProtKB:Q96PT3] xref: EMBL:AF133131 xref: HGNC:HGNC:3083 xref: UniGene:Hs.274469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058343 ! DUX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017643 name: DUXA_human def: "Double homeobox protein A gene" [UniProtKB:A6NLW8] xref: EMBL:AC025588 xref: HGNC:HGNC:32179 xref: UniGene:Hs.585857 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053901 ! DUXA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017644 name: DVL1L1_human def: "Segment polarity protein dishevelled homolog DVL-1-like gene" [UniProtKB:P54792] synonym: "DVL" EXACT [UniProtKB:P54792] synonym: "DVL1" EXACT [UniProtKB:P54792] xref: EMBL:U46461 xref: HGNC:HGNC:3085 xref: UniGene:Hs.702016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055516 ! DVL1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017645 name: DVL1_human def: "Segment polarity protein dishevelled homolog DVL-1 gene" [UniProtKB:O14640] xref: EMBL:AF006011 xref: EMBL:AL139287 xref: EMBL:BC050454 xref: EMBL:CH471183 xref: HGNC:HGNC:3084 xref: UniGene:Hs.702016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053884 ! A6NKG8_HUMAN relationship: codes_for CCO:B0054363 ! DVL1_HUMAN relationship: codes_for CCO:B0057238 ! Q86TH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017646 name: DVL3_human def: "Segment polarity protein dishevelled homolog DVL-3 gene" [UniProtKB:Q92997] synonym: "KIAA0208" EXACT [UniProtKB:Q92997] xref: EMBL:AF006013 xref: EMBL:BC032459 xref: EMBL:D86963 xref: EMBL:U49262 xref: EMBL:U75651 xref: HGNC:HGNC:3087 xref: UniGene:Hs.388116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058118 ! DVL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017647 name: DNAH12_human def: "Dynein heavy chain 12, axonemal gene" [UniProtKB:Q8WXK2] synonym: "ASB14" EXACT [UniProtKB:Q8WXK2] synonym: "DNAHC12" EXACT [UniProtKB:Q8WXK2] synonym: "DNAHC3" EXACT [UniProtKB:Q8WXK2] xref: EMBL:AC092418 xref: EMBL:AC093928 xref: EMBL:AC121250 xref: EMBL:AF403032 xref: EMBL:U53532 xref: HGNC:HGNC:2943 xref: UniGene:Hs.381296 xref: UniGene:Hs.665154 xref: UniGene:Hs.703052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058028 ! DYH12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017648 name: DNAH14_human def: "Dynein heavy chain 14, axonemal gene" [UniProtKB:Q0VDD8] synonym: "C1orf67" EXACT [UniProtKB:Q0VDD8] xref: EMBL:AC092811 xref: EMBL:AC093560 xref: EMBL:AL162738 xref: EMBL:AL357912 xref: EMBL:AL590547 xref: EMBL:AL596134 xref: EMBL:AL645769 xref: EMBL:BC119716 xref: EMBL:BC119717 xref: EMBL:CH471098 xref: HGNC:HGNC:2945 xref: UniGene:Hs.133977 xref: UniGene:Hs.655805 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055823 ! DYH14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017649 name: DYRK1B_human def: "Dual specificity tyrosine-phosphorylation-regulated kinase 1B gene" [UniProtKB:Q9Y463] synonym: "MIRK" EXACT [UniProtKB:Q9Y463] xref: EMBL:AC005393 xref: EMBL:AF205861 xref: EMBL:BC018751 xref: EMBL:BC025291 xref: EMBL:Y17999 xref: HGNC:HGNC:3092 xref: UniGene:Hs.130988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059349 ! DYR1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017650 name: EIF2AK4_human def: "Eukaryotic translation initiation factor 2-alpha kinase 4 gene" [UniProtKB:Q9P2K8] synonym: "GCN2" EXACT [UniProtKB:Q9P2K8] synonym: "KIAA1338" EXACT [UniProtKB:Q9P2K8] xref: EMBL:AB037759 xref: EMBL:AJ243428 xref: EMBL:AK027011 xref: EMBL:AL137627 xref: EMBL:AL157497 xref: EMBL:AL832907 xref: EMBL:BC009350 xref: EMBL:BC078179 xref: HGNC:HGNC:19687 xref: UniGene:Hs.656673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059059 ! E2AK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017651 name: EAF2_human def: "ELL-associated factor 2 gene" [UniProtKB:Q96CJ1] synonym: "BM-040" EXACT [UniProtKB:Q96CJ1] synonym: "TRAITS" EXACT [UniProtKB:Q96CJ1] xref: EMBL:AF217516 xref: EMBL:AF517829 xref: EMBL:AY049020 xref: EMBL:BC014209 xref: HGNC:HGNC:23115 xref: UniGene:Hs.477325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058183 ! EAF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017652 name: ECEL1_human def: "Endothelin-converting enzyme-like 1 gene" [UniProtKB:O95672] synonym: "UNQ2431/PRO4991" EXACT [UniProtKB:O95672] synonym: "XCE" EXACT [UniProtKB:O95672] xref: EMBL:AC092165 xref: EMBL:AJ130734 xref: EMBL:AY358923 xref: EMBL:BC050453 xref: EMBL:DQ114476 xref: EMBL:Y16187 xref: HGNC:HGNC:3147 xref: UniGene:Hs.26880 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054781 ! ECEL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017653 name: ECM1_human def: "Extracellular matrix protein 1 precursor gene" [UniProtKB:Q16610] xref: EMBL:U65932 xref: EMBL:U65933 xref: EMBL:U65934 xref: EMBL:U65935 xref: EMBL:U65936 xref: EMBL:U65937 xref: EMBL:U65938 xref: EMBL:U68186 xref: HGNC:HGNC:3153 xref: UniGene:Hs.81071 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056158 ! ECM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017654 name: ECOP_human def: "EGFR-coamplified and overexpressed protein precursor gene" [UniProtKB:Q96AW1] synonym: "GASP" EXACT [UniProtKB:Q96AW1] xref: EMBL:AB097004 xref: EMBL:AF395824 xref: EMBL:AK075391 xref: EMBL:AL136610 xref: EMBL:BC016650 xref: EMBL:CH236957 xref: EMBL:CH471201 xref: EMBL:CR533483 xref: UniGene:Hs.610460 xref: UniGene:Hs.705409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058156 ! ECOP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017655 name: EDARADD_human def: "Ectodysplasin-A receptor-associated adapter protein gene" [UniProtKB:Q8WWZ3] xref: EMBL:AL136105 xref: EMBL:AL354693 xref: EMBL:AY028906 xref: EMBL:AY028907 xref: EMBL:AY028908 xref: EMBL:AY028909 xref: EMBL:AY028910 xref: EMBL:AY028911 xref: EMBL:AY028912 xref: EMBL:AY028913 xref: EMBL:AY028914 xref: EMBL:AY071862 xref: HGNC:HGNC:14341 xref: UniGene:Hs.352224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058009 ! EDAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017656 name: EDAR_human def: "Tumor necrosis factor receptor superfamily member EDAR precursor gene" [UniProtKB:Q9UNE0] synonym: "DL" EXACT [UniProtKB:Q9UNE0] xref: EMBL:AF130988 xref: EMBL:AF130990 xref: EMBL:AF130991 xref: EMBL:AF130992 xref: EMBL:AF130993 xref: EMBL:AF130994 xref: EMBL:AF130995 xref: EMBL:AF130996 xref: EMBL:BC093870 xref: EMBL:BC093872 xref: HGNC:HGNC:2895 xref: UniGene:Hs.171971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059250 ! EDAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017657 name: EDA_human def: "Ectodysplasin-A gene" [UniProtKB:Q92838] synonym: "ED1" EXACT [UniProtKB:Q92838] synonym: "EDA2" EXACT [UniProtKB:Q92838] xref: EMBL:AF040628 xref: EMBL:AF060992 xref: EMBL:AF060993 xref: EMBL:AF060994 xref: EMBL:AF060995 xref: EMBL:AF060996 xref: EMBL:AF060997 xref: EMBL:AF060998 xref: EMBL:AF060999 xref: EMBL:AF061189 xref: EMBL:AF061190 xref: EMBL:AF061191 xref: EMBL:AF061192 xref: EMBL:AF061193 xref: EMBL:AF061194 xref: EMBL:AL158069 xref: EMBL:AL158141 xref: EMBL:AL450449 xref: EMBL:BC126143 xref: EMBL:U59227 xref: EMBL:U59228 xref: HGNC:HGNC:3157 xref: UniGene:Hs.105407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058102 ! EDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017658 name: EDF1_human def: "Endothelial differentiation-related factor 1 gene" [UniProtKB:O60869] xref: EMBL:AB002282 xref: EMBL:AB002283 xref: EMBL:AJ005259 xref: EMBL:AL355987 xref: EMBL:BC015500 xref: EMBL:BT009863 xref: EMBL:CR541914 xref: HGNC:HGNC:3164 xref: UniGene:Hs.174050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054582 ! EDF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017659 name: EDN2_human def: "Endothelin-2 precursor gene" [UniProtKB:P20800] xref: EMBL:AY518541 xref: EMBL:BC034393 xref: EMBL:M25550 xref: EMBL:M65199 xref: EMBL:X55177 xref: HGNC:HGNC:3177 xref: UniGene:Hs.1407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055125 ! EDN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017660 name: EDRF1_human def: "Erythroid differentiation-related factor 1 gene" [UniProtKB:Q3B7T1] synonym: "C10orf137" EXACT [UniProtKB:Q3B7T1] xref: EMBL:AL050102 xref: EMBL:AL158835 xref: EMBL:BC016903 xref: EMBL:BC026172 xref: EMBL:BC105929 xref: EMBL:BC107479 xref: HGNC:HGNC:24640 xref: UniGene:Hs.468688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056245 ! EDRF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017661 name: EEF1D_human def: "Elongation factor 1-delta gene" [UniProtKB:P29692] synonym: "EF1D" EXACT [UniProtKB:P29692] xref: EMBL:BC007847 xref: EMBL:BC009907 xref: EMBL:BC012819 xref: EMBL:BC062535 xref: EMBL:BT007242 xref: EMBL:CH471162 xref: EMBL:Z21507 xref: HGNC:HGNC:3211 xref: UniGene:Hs.333388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021069 ! EF1D_HUMAN relationship: codes_for CCO:B0021083 ! Q96I38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017662 name: EFCAB6_human def: "EF-hand calcium-binding domain-containing protein 6 gene" [UniProtKB:Q5THR3] synonym: "DJBP" EXACT [UniProtKB:Q5THR3] synonym: "KIAA1672" EXACT [UniProtKB:Q5THR3] xref: EMBL:AB051459 xref: EMBL:AB073862 xref: EMBL:AK027241 xref: EMBL:AK292411 xref: EMBL:AK292498 xref: EMBL:AL023801 xref: EMBL:AL031843 xref: EMBL:AL118498 xref: EMBL:AL355841 xref: EMBL:BC039315 xref: EMBL:Z82201 xref: EMBL:Z97055 xref: HGNC:HGNC:24204 xref: UniGene:Hs.658996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056628 ! EFCB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017663 name: EFNB3_human def: "Ephrin-B3 precursor gene" [UniProtKB:Q15768] synonym: "EPLG8" EXACT [UniProtKB:Q15768] synonym: "LERK8" EXACT [UniProtKB:Q15768] xref: EMBL:BC022499 xref: EMBL:BC042944 xref: EMBL:U57001 xref: EMBL:U62775 xref: EMBL:U66406 xref: HGNC:HGNC:3228 xref: UniGene:Hs.26988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056107 ! EFNB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017664 name: ENG_human def: "Endoglin precursor gene" [UniProtKB:P17813] synonym: "END" EXACT [UniProtKB:P17813] xref: EMBL:AF036969 xref: EMBL:AF036970 xref: EMBL:AF036971 xref: EMBL:J05481 xref: EMBL:U37439 xref: EMBL:U37441 xref: EMBL:U37442 xref: EMBL:U37445 xref: EMBL:U37446 xref: EMBL:U37447 xref: EMBL:X72012 xref: HGNC:HGNC:3349 xref: UniGene:Hs.76753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055092 ! EGLN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017665 name: EGR1_human def: "Early growth response protein 1 gene" [UniProtKB:P18146] synonym: "ZNF225" EXACT [UniProtKB:P18146] xref: EMBL:BC073983 xref: EMBL:M62829 xref: EMBL:M80583 xref: EMBL:X52541 xref: HGNC:HGNC:3238 xref: UniGene:Hs.326035 xref: UniGene:Hs.653544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055100 ! EGR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017666 name: EGR3_human def: "Early growth response protein 3 gene" [UniProtKB:Q06889] synonym: "PILOT" EXACT [UniProtKB:Q06889] xref: EMBL:BC104765 xref: EMBL:BC112279 xref: EMBL:S40832 xref: EMBL:X63741 xref: HGNC:HGNC:3240 xref: UniGene:Hs.534313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055776 ! EGR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017667 name: EGR4_human def: "Early growth response protein 4 gene" [UniProtKB:Q05215] xref: EMBL:AC010913 xref: EMBL:X60104 xref: EMBL:X69438 xref: HGNC:HGNC:3241 xref: UniGene:Hs.3052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055741 ! EGR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017668 name: EHF_human def: "ETS homologous factor gene" [UniProtKB:Q9NZC4] synonym: "ESE3" EXACT [UniProtKB:Q9NZC4] synonym: "ESE3B" EXACT [UniProtKB:Q9NZC4] synonym: "ESEJ" EXACT [UniProtKB:Q9NZC4] xref: EMBL:AF124438 xref: EMBL:AF124439 xref: EMBL:AF170583 xref: EMBL:AF203977 xref: EMBL:AF212848 xref: EMBL:AL157952 xref: EMBL:AY882601 xref: EMBL:BC038995 xref: HGNC:HGNC:3246 xref: UniGene:Hs.653859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058991 ! EHF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017669 name: EI24_human def: "Etoposide-induced protein 2.4 homolog gene" [UniProtKB:O14681] synonym: "PIG8" EXACT [UniProtKB:O14681] xref: EMBL:AF010313 xref: EMBL:AK291951 xref: EMBL:AK315841 xref: EMBL:BC002390 xref: EMBL:CH471065 xref: HGNC:HGNC:13276 xref: UniGene:Hs.702058 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054365 ! EI24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017670 name: EIF2B2_human def: "Translation initiation factor eIF-2B subunit beta gene" [UniProtKB:P49770] synonym: "EIF2BB" EXACT [UniProtKB:P49770] xref: EMBL:AC006530 xref: EMBL:AF035280 xref: EMBL:BC011750 xref: EMBL:L40395 xref: HGNC:HGNC:3258 xref: UniGene:Hs.409137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055434 ! EI2BB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017671 name: EIF2B4_human def: "Translation initiation factor eIF-2B subunit delta gene" [UniProtKB:Q9UI10] synonym: "EIF2BD" EXACT [UniProtKB:Q9UI10] xref: EMBL:AF112207 xref: EMBL:AJ011305 xref: EMBL:AJ011306 xref: EMBL:AJ011307 xref: EMBL:AJ011308 xref: EMBL:BC001870 xref: EMBL:BC091502 xref: HGNC:HGNC:3260 xref: UniGene:Hs.169474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059154 ! EI2BD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017672 name: EIF2B5_human def: "Translation initiation factor eIF-2B subunit epsilon gene" [UniProtKB:Q13144] synonym: "EIF2BE" EXACT [UniProtKB:Q13144] xref: EMBL:AC131235 xref: EMBL:BC013590 xref: EMBL:U23028 xref: HGNC:HGNC:3261 xref: UniGene:Hs.283551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055879 ! EI2BE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017673 name: EID2B_human def: "EP300-interacting inhibitor of differentiation 2B gene" [UniProtKB:Q96D98] synonym: "EID3" EXACT [UniProtKB:Q96D98] xref: EMBL:AK096263 xref: EMBL:BC009725 xref: EMBL:CH471126 xref: HGNC:HGNC:26796 xref: UniGene:Hs.135181 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058190 ! EID2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017674 name: EID2_human def: "EP300-interacting inhibitor of differentiation 2 gene" [UniProtKB:Q8N6I1] synonym: "CRI2" EXACT [UniProtKB:Q8N6I1] xref: EMBL:AK128468 xref: EMBL:AY251272 xref: EMBL:BC030137 xref: EMBL:BC099899 xref: EMBL:CH471126 xref: HGNC:HGNC:28292 xref: UniGene:Hs.18949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057490 ! EID2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017675 name: EIF1B_human def: "Eukaryotic translation initiation factor 1b gene" [UniProtKB:O60739] xref: EMBL:AF064607 xref: EMBL:AF077052 xref: EMBL:AF263452 xref: EMBL:BC006996 xref: HGNC:HGNC:30792 xref: UniGene:Hs.315230 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019930 ! EIF1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017676 name: EIF1_human def: "Eukaryotic translation initiation factor 1 gene" [UniProtKB:P41567] synonym: "SUI1" EXACT [UniProtKB:P41567] xref: EMBL:AF083441 xref: EMBL:AF100737 xref: EMBL:BC005118 xref: EMBL:BC008710 xref: EMBL:L26247 xref: HGNC:HGNC:3249 xref: UniGene:Hs.150580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019928 ! EIF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017677 name: EIF2A_human def: "Eukaryotic translation initiation factor 2A gene" [UniProtKB:Q9BY44] synonym: "CDA02" EXACT [UniProtKB:Q9BY44] synonym: "MSTP004" EXACT [UniProtKB:Q9BY44] synonym: "MSTP089" EXACT [UniProtKB:Q9BY44] xref: EMBL:AF109358 xref: EMBL:AF172818 xref: EMBL:AF212241 xref: EMBL:AF497978 xref: EMBL:AK027356 xref: EMBL:BC011885 xref: HGNC:HGNC:3254 xref: UniGene:Hs.655782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058570 ! EIF2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017678 name: EIF3A_human def: "Eukaryotic translation initiation factor 3 subunit A gene" [UniProtKB:Q14152] synonym: "EIF3S10" EXACT [UniProtKB:Q14152] synonym: "KIAA0139" EXACT [UniProtKB:Q14152] xref: EMBL:D50929 xref: EMBL:U58046 xref: EMBL:U58047 xref: EMBL:U78311 xref: HGNC:HGNC:3271 xref: UniGene:Hs.523299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055965 ! EIF3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017679 name: EIF3H_human def: "Eukaryotic translation initiation factor 3 subunit H gene" [UniProtKB:O15372] synonym: "EIF3S3" EXACT [UniProtKB:O15372] xref: EMBL:AF092569 xref: EMBL:AF092570 xref: EMBL:AF092571 xref: EMBL:AF092572 xref: EMBL:AF092573 xref: EMBL:AF092574 xref: EMBL:AF092575 xref: EMBL:AF092576 xref: EMBL:BC000386 xref: EMBL:U54559 xref: HGNC:HGNC:3273 xref: UniGene:Hs.492599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054433 ! EIF3H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017680 name: ELAVL1_human def: "ELAV-like protein 1 gene" [UniProtKB:Q15717] synonym: "HUR" EXACT [UniProtKB:Q15717] xref: EMBL:BC003376 xref: EMBL:U38175 xref: HGNC:HGNC:3312 xref: UniGene:Hs.184492 xref: UniGene:Hs.660070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056099 ! ELAV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017681 name: ELAVL2_human def: "ELAV-like protein 2 gene" [UniProtKB:Q12926] synonym: "HUB" EXACT [UniProtKB:Q12926] xref: EMBL:AB209294 xref: EMBL:AL161628 xref: EMBL:AL445623 xref: EMBL:BC030692 xref: EMBL:U12431 xref: EMBL:U29943 xref: HGNC:HGNC:3313 xref: UniGene:Hs.166109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055858 ! ELAV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017682 name: ELF2_human def: "ETS-related transcription factor Elf-2 gene" [UniProtKB:Q15723] synonym: "NERF" EXACT [UniProtKB:Q15723] xref: EMBL:AF256222 xref: EMBL:AF256223 xref: EMBL:BC034951 xref: EMBL:BC065025 xref: EMBL:U43188 xref: EMBL:U43189 xref: HGNC:HGNC:3317 xref: UniGene:Hs.699401 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056101 ! ELF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017683 name: ELF3_human def: "ETS-related transcription factor Elf-3 gene" [UniProtKB:P78545] synonym: "ERT" EXACT [UniProtKB:P78545] synonym: "ESX" EXACT [UniProtKB:P78545] synonym: "JEN" EXACT [UniProtKB:P78545] xref: EMBL:AF016295 xref: EMBL:AF017307 xref: EMBL:AF110184 xref: EMBL:AF517841 xref: EMBL:AL691482 xref: EMBL:BC003569 xref: EMBL:BN000001 xref: EMBL:BX537368 xref: EMBL:CR457106 xref: EMBL:U66894 xref: EMBL:U73843 xref: EMBL:U73844 xref: EMBL:U97156 xref: HGNC:HGNC:3318 xref: UniGene:Hs.67928 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055650 ! ELF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017684 name: ELF4_human def: "ETS-related transcription factor Elf-4 gene" [UniProtKB:Q99607] synonym: "ELFR" EXACT [UniProtKB:Q99607] synonym: "MEF" EXACT [UniProtKB:Q99607] xref: EMBL:AF000670 xref: EMBL:AL136450 xref: EMBL:BC017194 xref: EMBL:U32645 xref: EMBL:Z81363 xref: HGNC:HGNC:3319 xref: UniGene:Hs.271940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058430 ! ELF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017685 name: ELF5_human def: "ETS-related transcription factor Elf-5 gene" [UniProtKB:Q9UKW6] synonym: "ESE2" EXACT [UniProtKB:Q9UKW6] xref: EMBL:AF049703 xref: EMBL:AF115402 xref: EMBL:AF115403 xref: EMBL:AK074633 xref: EMBL:AL137224 xref: EMBL:BC029743 xref: EMBL:DQ123839 xref: HGNC:HGNC:3320 xref: UniGene:Hs.11713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053940 ! A6XAE6_HUMAN relationship: codes_for CCO:B0059208 ! ELF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017686 name: ELK3_human def: "ETS domain-containing protein Elk-3 gene" [UniProtKB:P41970] synonym: "NET" EXACT [UniProtKB:P41970] synonym: "SAP2" EXACT [UniProtKB:P41970] xref: EMBL:BC017371 xref: EMBL:CR542251 xref: EMBL:Z36715 xref: HGNC:HGNC:3325 xref: UniGene:Hs.591015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055345 ! ELK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017687 name: ELK4_human def: "ETS domain-containing protein Elk-4 gene" [UniProtKB:P28324] synonym: "SAP1" EXACT [UniProtKB:P28324] xref: EMBL:M85164 xref: EMBL:M85165 xref: HGNC:HGNC:3326 xref: UniGene:Hs.497520 xref: UniGene:Hs.602654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055200 ! ELK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017688 name: ELL2_human def: "RNA polymerase II elongation factor ELL2 gene" [UniProtKB:O00472] xref: EMBL:BC028412 xref: EMBL:U88629 xref: HGNC:HGNC:17064 xref: UniGene:Hs.592742 xref: UniGene:Hs.653894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054324 ! ELL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017689 name: ELL3_human def: "RNA polymerase II elongation factor ELL3 gene" [UniProtKB:Q9HB65] xref: EMBL:AF276512 xref: EMBL:AK026290 xref: EMBL:BC006548 xref: EMBL:BC019293 xref: HGNC:HGNC:23113 xref: UniGene:Hs.699876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058778 ! ELL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017690 name: ELL_human def: "RNA polymerase II elongation factor ELL gene" [UniProtKB:P55199] synonym: "C19orf17" EXACT [UniProtKB:P55199] xref: EMBL:BC049195 xref: EMBL:U16282 xref: HGNC:HGNC:23114 xref: UniGene:Hs.515260 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055529 ! ELL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017691 name: ELA2_human def: "Leukocyte elastase precursor gene" [UniProtKB:P08246] xref: EMBL:AY596461 xref: EMBL:BC074816 xref: EMBL:BC074817 xref: EMBL:D00187 xref: EMBL:J03545 xref: EMBL:M20199 xref: EMBL:M20200 xref: EMBL:M20201 xref: EMBL:M20203 xref: EMBL:M27783 xref: EMBL:M34379 xref: EMBL:X05875 xref: EMBL:Y00477 xref: HGNC:HGNC:3309 xref: UniGene:Hs.99863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054926 ! ELNE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017692 name: ELN_human def: "Elastin precursor gene" [UniProtKB:P15502] xref: EMBL:AC005056 xref: EMBL:AK122731 xref: EMBL:BC065566 xref: EMBL:BX537939 xref: EMBL:BX538199 xref: EMBL:M16983 xref: EMBL:M17265 xref: EMBL:M17266 xref: EMBL:M17267 xref: EMBL:M17268 xref: EMBL:M17270 xref: EMBL:M17271 xref: EMBL:M17272 xref: EMBL:M17273 xref: EMBL:M17274 xref: EMBL:M17275 xref: EMBL:M17276 xref: EMBL:M17277 xref: EMBL:M17278 xref: EMBL:M17279 xref: EMBL:M17280 xref: EMBL:M17281 xref: EMBL:M17282 xref: EMBL:M24782 xref: EMBL:M36860 xref: EMBL:U62292 xref: EMBL:U63721 xref: EMBL:U93034 xref: EMBL:U93035 xref: EMBL:U93036 xref: EMBL:U93037 xref: EMBL:X15603 xref: HGNC:HGNC:3327 xref: UniGene:Hs.647061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055038 ! ELN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017693 name: TCEB3_human def: "Transcription elongation factor B polypeptide 3 gene" [UniProtKB:Q14241] synonym: "MSTP059" EXACT [UniProtKB:Q14241] xref: EMBL:AF116729 xref: EMBL:AL031295 xref: EMBL:BC002883 xref: EMBL:L47345 xref: HGNC:HGNC:11620 xref: UniGene:Hs.584806 xref: UniGene:Hs.621226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055974 ! ELOA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017694 name: TCEB3B_human def: "RNA polymerase II transcription factor SIII subunit A2 gene" [UniProtKB:Q8IYF1] synonym: "TCEB3L" EXACT [UniProtKB:Q8IYF1] xref: EMBL:AB030834 xref: EMBL:BC036022 xref: HGNC:HGNC:30771 xref: UniGene:Hs.375035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057386 ! ELOA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017695 name: TCEB3C_human def: "RNA polymerase II transcription factor SIII subunit A3 gene" [UniProtKB:Q8NG57] synonym: "TCEB3L2" EXACT [UniProtKB:Q8NG57] xref: EMBL:AB076840 xref: HGNC:HGNC:24617 xref: UniGene:Hs.515381 xref: UniGene:Hs.631674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057613 ! ELOA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017696 name: ELOF1_human def: "Transcription elongation factor 1 homolog gene" [UniProtKB:P60002] xref: EMBL:BC007516 xref: HGNC:HGNC:28691 xref: UniGene:Hs.631633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055594 ! ELOF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017697 name: ELP3_human def: "Elongator complex protein 3 gene" [UniProtKB:Q9H9T3] xref: EMBL:AK001284 xref: EMBL:AK022626 xref: EMBL:AK223047 xref: EMBL:AL834273 xref: EMBL:BC001240 xref: EMBL:BX648011 xref: HGNC:HGNC:20696 xref: UniGene:Hs.491336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058757 ! ELP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017698 name: ELP4_human def: "Elongator complex protein 4 gene" [UniProtKB:Q96EB1] synonym: "C11orf19" EXACT [UniProtKB:Q96EB1] synonym: "PAXNEB" EXACT [UniProtKB:Q96EB1] xref: EMBL:AJ276005 xref: EMBL:AK000505 xref: EMBL:AL136677 xref: EMBL:BC012514 xref: EMBL:Z83307 xref: HGNC:HGNC:1171 xref: UniGene:Hs.175534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058203 ! ELP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017699 name: ELTD1_human def: "EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor gene" [UniProtKB:Q9HBW9] synonym: "ETL" EXACT [UniProtKB:Q9HBW9] synonym: "UNQ202/PRO228" EXACT [UniProtKB:Q9HBW9] xref: EMBL:AC098651 xref: EMBL:AC099674 xref: EMBL:AF192403 xref: EMBL:AL596269 xref: EMBL:AY358360 xref: EMBL:BC025721 xref: EMBL:CH471059 xref: HGNC:HGNC:20822 xref: UniGene:Hs.132314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058793 ! ELTD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017700 name: MPP1_human def: "55 kDa erythrocyte membrane protein gene" [UniProtKB:Q00013] synonym: "DXS552E" EXACT [UniProtKB:Q00013] synonym: "EMP55" EXACT [UniProtKB:Q00013] xref: EMBL:BC002392 xref: EMBL:M64925 xref: EMBL:M87059 xref: EMBL:U39611 xref: HGNC:HGNC:7219 xref: UniGene:Hs.496984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019045 ! EM55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017701 name: EMP1_human def: "Epithelial membrane protein 1 gene" [UniProtKB:P54849] synonym: "B4B" EXACT [UniProtKB:P54849] synonym: "TMP" EXACT [UniProtKB:P54849] xref: EMBL:BC047300 xref: EMBL:U43916 xref: EMBL:U77085 xref: EMBL:Y07909 xref: EMBL:Z50751 xref: HGNC:HGNC:3333 xref: UniGene:Hs.705477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055519 ! EMP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017702 name: EMP2_human def: "Epithelial membrane protein 2 gene" [UniProtKB:P54851] synonym: "XMP" EXACT [UniProtKB:P54851] xref: EMBL:AY057060 xref: EMBL:BC009687 xref: EMBL:U52100 xref: EMBL:X94770 xref: HGNC:HGNC:3334 xref: UniGene:Hs.531561 xref: UniGene:Hs.655130 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055520 ! EMP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017703 name: EMP3_human def: "Epithelial membrane protein 3 gene" [UniProtKB:P54852] synonym: "YMP" EXACT [UniProtKB:P54852] xref: EMBL:BC009718 xref: EMBL:BT007124 xref: EMBL:U52101 xref: EMBL:U87947 xref: EMBL:X94771 xref: HGNC:HGNC:3335 xref: UniGene:Hs.9999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055521 ! EMP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017704 name: EMR1_human def: "EGF-like module-containing mucin-like hormone receptor-like 1 precursor gene" [UniProtKB:Q14246] synonym: "TM7LN3" EXACT [UniProtKB:Q14246] xref: EMBL:AB065918 xref: EMBL:AC020895 xref: EMBL:BC059395 xref: EMBL:DQ217942 xref: EMBL:X81479 xref: HGNC:HGNC:3336 xref: UniGene:Hs.2375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055975 ! EMR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017705 name: EMR2_human def: "EGF-like module-containing mucin-like hormone receptor-like 2 precursor gene" [UniProtKB:Q9UHX3] xref: EMBL:AB065931 xref: EMBL:AC004262 xref: EMBL:AF114491 xref: HGNC:HGNC:3337 xref: UniGene:Hs.531619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059152 ! EMR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017706 name: EMR3_human def: "EGF-like module-containing mucin-like hormone receptor-like 3 precursor gene" [UniProtKB:Q9BY15] synonym: "UNQ683/PRO1562" EXACT [UniProtKB:Q9BY15] xref: EMBL:AF239764 xref: EMBL:AY358817 xref: EMBL:BC121131 xref: HGNC:HGNC:23647 xref: UniGene:Hs.658712 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055813 ! Q0IJ52_HUMAN relationship: codes_for CCO:B0058565 ! EMR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017707 name: EMR4P_human def: "Putative EGF-like module-containing mucin-like hormone receptor-like 4 precursor gene" [UniProtKB:Q86SQ3] synonym: "EMR4" EXACT [UniProtKB:Q86SQ3] synonym: "GPR127" EXACT [UniProtKB:Q86SQ3] synonym: "PGR16" EXACT [UniProtKB:Q86SQ3] xref: EMBL:AF489700 xref: EMBL:AY181245 xref: EMBL:AY255550 xref: HGNC:HGNC:19240 xref: UniGene:Hs.688043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057232 ! EMR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017708 name: EMSY_human def: "Protein EMSY gene" [UniProtKB:Q7Z589] synonym: "C11orf30" EXACT [UniProtKB:Q7Z589] synonym: "GL002" EXACT [UniProtKB:Q7Z589] xref: EMBL:AF226047 xref: EMBL:AJ430203 xref: EMBL:AK023651 xref: EMBL:AK075222 xref: EMBL:AY070433 xref: EMBL:BC029375 xref: EMBL:BC033404 xref: HGNC:HGNC:18071 xref: UniGene:Hs.352588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057175 ! EMSY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017709 name: EMX1_human def: "Homeobox protein EMX1 gene" [UniProtKB:Q04741] xref: EMBL:AC012366 xref: EMBL:BC037242 xref: EMBL:BC045762 xref: EMBL:X68879 xref: HGNC:HGNC:3340 xref: UniGene:Hs.516090 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055733 ! EMX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017710 name: EMX2_human def: "Homeobox protein EMX2 gene" [UniProtKB:Q04743] xref: EMBL:AF301598 xref: EMBL:AK055041 xref: EMBL:AL161811 xref: EMBL:X68880 xref: HGNC:HGNC:3341 xref: UniGene:Hs.202095 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055734 ! EMX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017711 name: MLLT1_human def: "Protein ENL gene" [UniProtKB:Q03111] synonym: "ENL" EXACT [UniProtKB:Q03111] synonym: "LTG19" EXACT [UniProtKB:Q03111] synonym: "YEATS1" EXACT [UniProtKB:Q03111] xref: EMBL:D14539 xref: EMBL:L04285 xref: HGNC:HGNC:7134 xref: UniGene:Hs.705366 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055720 ! ENL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017712 name: ENOX2_human def: "Ecto-NOX disulfide-thiol exchanger 2 gene" [UniProtKB:Q16206] synonym: "COVA1" EXACT [UniProtKB:Q16206] xref: EMBL:AF207881 xref: EMBL:AK000353 xref: EMBL:AL049733 xref: EMBL:AL133207 xref: EMBL:AL591908 xref: EMBL:BC019254 xref: EMBL:S72904 xref: HGNC:HGNC:2259 xref: UniGene:Hs.171458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056127 ! ENOX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017713 name: HSP90B1_human def: "Endoplasmin precursor gene" [UniProtKB:P14625] synonym: "TRA1" EXACT [UniProtKB:P14625] xref: EMBL:AY040226 xref: EMBL:BC066656 xref: EMBL:M26596 xref: EMBL:M33716 xref: EMBL:X15187 xref: HGNC:HGNC:12028 xref: UniGene:Hs.192374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055025 ! ENPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017714 name: ENPP1_human def: "Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 gene" [UniProtKB:P22413] synonym: "M6S1" EXACT [UniProtKB:P22413] synonym: "NPPS" EXACT [UniProtKB:P22413] synonym: "PC1" EXACT [UniProtKB:P22413] synonym: "PDNP1" EXACT [UniProtKB:P22413] xref: EMBL:AF067177 xref: EMBL:AF067178 xref: EMBL:AF110280 xref: EMBL:AF110281 xref: EMBL:AF110283 xref: EMBL:AF110284 xref: EMBL:AF110285 xref: EMBL:AF110286 xref: EMBL:AF110287 xref: EMBL:AF110288 xref: EMBL:AF110289 xref: EMBL:AF110290 xref: EMBL:AF110291 xref: EMBL:AF110292 xref: EMBL:AF110293 xref: EMBL:AF110294 xref: EMBL:AF110295 xref: EMBL:AF110296 xref: EMBL:AF110297 xref: EMBL:AF110298 xref: EMBL:AF110299 xref: EMBL:AF110300 xref: EMBL:AF110301 xref: EMBL:AF110302 xref: EMBL:AF110303 xref: EMBL:AF110304 xref: EMBL:AJ242020 xref: EMBL:AJ242021 xref: EMBL:AJ242022 xref: EMBL:AJ242023 xref: EMBL:AJ242024 xref: EMBL:AJ242025 xref: EMBL:AJ242026 xref: EMBL:AJ242027 xref: EMBL:AJ242028 xref: EMBL:AJ242029 xref: EMBL:AJ242030 xref: EMBL:AJ242031 xref: EMBL:AJ242032 xref: EMBL:AJ242033 xref: EMBL:AJ242034 xref: EMBL:AJ242035 xref: EMBL:AJ242036 xref: EMBL:AJ242037 xref: EMBL:AJ242038 xref: EMBL:AJ242039 xref: EMBL:AJ242040 xref: EMBL:AJ242041 xref: EMBL:AJ242042 xref: EMBL:AJ242043 xref: EMBL:AJ242044 xref: EMBL:AL117378 xref: EMBL:AL139805 xref: EMBL:BC059375 xref: EMBL:D12485 xref: EMBL:M57736 xref: HGNC:HGNC:3356 xref: UniGene:Hs.527295 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055145 ! ENPP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017715 name: ENPP2_human def: "Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 precursor gene" [UniProtKB:Q13822] synonym: "ATX" EXACT [UniProtKB:Q13822] synonym: "PDNP2" EXACT [UniProtKB:Q13822] xref: EMBL:BC034961 xref: EMBL:D45421 xref: EMBL:D45914 xref: EMBL:L35594 xref: EMBL:L46720 xref: HGNC:HGNC:3357 xref: UniGene:Hs.190977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055945 ! ENPP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017716 name: ENPP7_human def: "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 precursor gene" [UniProtKB:Q6UWV6] synonym: "UNQ3077/PRO9912" EXACT [UniProtKB:Q6UWV6] xref: EMBL:AK126250 xref: EMBL:AY230663 xref: EMBL:AY358622 xref: EMBL:BC041453 xref: HGNC:HGNC:23764 xref: UniGene:Hs.114084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056953 ! ENPP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017717 name: ENY2_human def: "Enhancer of yellow 2 transcription factor homolog gene" [UniProtKB:Q9NPA8] synonym: "DC6" EXACT [UniProtKB:Q9NPA8] xref: EMBL:AF173296 xref: EMBL:AF201940 xref: EMBL:AK290752 xref: EMBL:BC007870 xref: EMBL:CH471060 xref: EMBL:CR457183 xref: HGNC:HGNC:24449 xref: UniGene:Hs.492555 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058843 ! ENY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017718 name: EOMES_human def: "Eomesodermin homolog gene" [UniProtKB:O95936] synonym: "TBR2" EXACT [UniProtKB:O95936] xref: EMBL:AB031038 xref: EMBL:AJ010280 xref: EMBL:BC025363 xref: HGNC:HGNC:3372 xref: UniGene:Hs.591663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054806 ! EOMES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017719 name: EPAG_human def: "Early lymphoid activation gene" [UniProtKB:Q14236] xref: EMBL:AL391821 xref: EMBL:L22650 xref: UniGene:Hs.654372 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055973 ! EPAG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017720 name: EPB42_human def: "Erythrocyte membrane protein band 4.2 gene" [UniProtKB:P16452] synonym: "E42P" EXACT [UniProtKB:P16452] xref: EMBL:AC068724 xref: EMBL:L06447 xref: EMBL:L06448 xref: EMBL:L06449 xref: EMBL:L06450 xref: EMBL:L06511 xref: EMBL:L06512 xref: EMBL:L06513 xref: EMBL:L06515 xref: EMBL:L06516 xref: EMBL:L06517 xref: EMBL:L06518 xref: EMBL:L06519 xref: EMBL:M29399 xref: EMBL:M30646 xref: EMBL:M30647 xref: EMBL:M60298 xref: HGNC:HGNC:3381 xref: UniGene:Hs.368642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055051 ! EPB42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017721 name: EPOR_human def: "Erythropoietin receptor precursor gene" [UniProtKB:P19235] xref: EMBL:BC112153 xref: EMBL:M34986 xref: EMBL:M60459 xref: EMBL:M76595 xref: EMBL:M77244 xref: EMBL:S45332 xref: EMBL:X57282 xref: HGNC:HGNC:3416 xref: UniGene:Hs.631624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055106 ! EPOR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017722 name: EPO_human def: "Erythropoietin precursor gene" [UniProtKB:P01588] xref: EMBL:AC009488 xref: EMBL:AF053356 xref: EMBL:AF202306 xref: EMBL:AF202307 xref: EMBL:AF202308 xref: EMBL:AF202309 xref: EMBL:AF202310 xref: EMBL:AF202311 xref: EMBL:AF202312 xref: EMBL:AF202313 xref: EMBL:AF202314 xref: EMBL:BC093628 xref: EMBL:BC111937 xref: EMBL:M11319 xref: EMBL:S65458 xref: EMBL:X02157 xref: EMBL:X02158 xref: HGNC:HGNC:3415 xref: UniGene:Hs.2303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054855 ! EPO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017723 name: EPS8_human def: "Epidermal growth factor receptor kinase substrate 8 gene" [UniProtKB:Q12929] xref: EMBL:AC092753 xref: EMBL:BC030010 xref: EMBL:CH471094 xref: EMBL:U12535 xref: HGNC:HGNC:3420 xref: UniGene:Hs.591160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019772 ! EPS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017724 name: ERCC6_human def: "DNA excision repair protein ERCC-6 gene" [UniProtKB:Q03468] synonym: "CSB" EXACT [UniProtKB:Q03468] xref: EMBL:AL138760 xref: EMBL:AY204752 xref: EMBL:L04791 xref: HGNC:HGNC:3438 xref: UniGene:Hs.654449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055725 ! ERCC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017725 name: ERCC8_human def: "DNA excision repair protein ERCC-8 gene" [UniProtKB:Q13216] synonym: "CKN1" EXACT [UniProtKB:Q13216] synonym: "CSA" EXACT [UniProtKB:Q13216] xref: EMBL:AY213194 xref: EMBL:BC009793 xref: EMBL:BT020021 xref: EMBL:CR536563 xref: EMBL:U28413 xref: HGNC:HGNC:3439 xref: UniGene:Hs.435237 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055887 ! ERCC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017726 name: ETF1_human def: "Eukaryotic peptide chain release factor subunit 1 gene" [UniProtKB:P62495] synonym: "ERF1" EXACT [UniProtKB:P62495] synonym: "RF1" EXACT [UniProtKB:P62495] synonym: "SUP45L1" EXACT [UniProtKB:P62495] xref: EMBL:AF095901 xref: EMBL:BC088358 xref: EMBL:M75715 xref: EMBL:U90176 xref: EMBL:X81625 xref: HGNC:HGNC:3477 xref: UniGene:Hs.483494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055619 ! ERF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017727 name: ERG_human def: "Transcriptional regulator ERG gene" [UniProtKB:P11308] xref: EMBL:AP001422 xref: EMBL:AY204741 xref: EMBL:AY204742 xref: EMBL:BC040168 xref: EMBL:M17254 xref: EMBL:M21535 xref: EMBL:S68130 xref: HGNC:HGNC:3446 xref: UniGene:Hs.473819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054090 ! A8MX39_HUMAN relationship: codes_for CCO:B0054991 ! ERG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017728 name: ESF1_human def: "ESF1 homolog gene" [UniProtKB:Q9H501] synonym: "ABTAP" EXACT [UniProtKB:Q9H501] synonym: "C20orf6" EXACT [UniProtKB:Q9H501] synonym: "HDCMC28P" EXACT [UniProtKB:Q9H501] xref: EMBL:AF068285 xref: EMBL:AK000375 xref: EMBL:AK022369 xref: EMBL:AK022670 xref: EMBL:AL161659 xref: EMBL:BC046107 xref: HGNC:HGNC:15898 xref: UniGene:Hs.369284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058722 ! ESF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017729 name: ESM1_human def: "Endothelial cell-specific molecule 1 precursor gene" [UniProtKB:Q9NQ30] xref: EMBL:AJ401091 xref: EMBL:AJ401092 xref: EMBL:AJ973643 xref: EMBL:AK300634 xref: EMBL:BC011989 xref: EMBL:X89426 xref: HGNC:HGNC:3466 xref: UniGene:Hs.129944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056277 ! Q3V4E3_HUMAN relationship: codes_for CCO:B0058859 ! ESM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017730 name: ESR2_human def: "Estrogen receptor beta gene" [UniProtKB:Q92731] synonym: "ESTRB" EXACT [UniProtKB:Q92731] synonym: "NR3A2" EXACT [UniProtKB:Q92731] xref: EMBL:AB006589 xref: EMBL:AB006590 xref: EMBL:AF047463 xref: EMBL:AF051427 xref: EMBL:AF051428 xref: EMBL:AF060555 xref: EMBL:AF061054 xref: EMBL:AF061055 xref: EMBL:AF074598 xref: EMBL:AF074599 xref: EMBL:AF124790 xref: EMBL:AF191544 xref: EMBL:AY785359 xref: EMBL:BC024181 xref: EMBL:X99101 xref: HGNC:HGNC:3468 xref: UniGene:Hs.525392 xref: UniGene:Hs.660607 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058084 ! ESR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017731 name: SMG6_human def: "Telomerase-binding protein EST1A gene" [UniProtKB:Q86US8] synonym: "C17orf31" EXACT [UniProtKB:Q86US8] synonym: "EST1A" EXACT [UniProtKB:Q86US8] synonym: "KIAA0732" EXACT [UniProtKB:Q86US8] xref: EMBL:AB018275 xref: EMBL:AL133597 xref: EMBL:AY145883 xref: EMBL:AY168921 xref: EMBL:BC064916 xref: HGNC:HGNC:17809 xref: UniGene:Hs.448342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057255 ! EST1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017732 name: ESX1_human def: "Homeobox protein ESX1 gene" [UniProtKB:Q8N693] synonym: "ESX1L" EXACT [UniProtKB:Q8N693] synonym: "ESX1R" EXACT [UniProtKB:Q8N693] xref: EMBL:AL049631 xref: EMBL:AY114148 xref: EMBL:BC042633 xref: EMBL:BC053599 xref: EMBL:CH471120 xref: EMBL:EF695416 xref: EMBL:EF695425 xref: HGNC:HGNC:14865 xref: UniGene:Hs.223782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022617 ! A6ZIS4_HUMAN relationship: codes_for CCO:B0022629 ! A6ZIT3_HUMAN relationship: codes_for CCO:B0054171 ! B0QYU3_HUMAN relationship: codes_for CCO:B0057485 ! ESX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017733 name: GPR37L1_human def: "Endothelin B receptor-like protein 2 precursor gene" [UniProtKB:O60883] synonym: "ETBRLP2" EXACT [UniProtKB:O60883] xref: EMBL:AK222639 xref: EMBL:AL592300 xref: EMBL:BC050334 xref: EMBL:Y16280 xref: HGNC:HGNC:14923 xref: UniGene:Hs.132049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054585 ! ETBR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017734 name: ETS1_human def: "Protein C-ets-1 gene" [UniProtKB:P14921] synonym: "EWSR2" EXACT [UniProtKB:P14921] xref: EMBL:BT019452 xref: EMBL:J04101 xref: EMBL:M11921 xref: EMBL:S67063 xref: EMBL:X14798 xref: EMBL:X65469 xref: HGNC:HGNC:3488 xref: UniGene:Hs.369438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030313 ! ETS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017735 name: ETS2_human def: "Protein C-ets-2 gene" [UniProtKB:P15036] xref: EMBL:AF017257 xref: EMBL:AK315563 xref: EMBL:AL163278 xref: EMBL:AP001040 xref: EMBL:AP001732 xref: EMBL:BC017040 xref: EMBL:BC042954 xref: EMBL:BT006838 xref: EMBL:CH471079 xref: EMBL:J04102 xref: EMBL:M11922 xref: EMBL:X55181 xref: HGNC:HGNC:3489 xref: UniGene:Hs.695937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030316 ! ETS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017736 name: ETV1_human def: "ETS translocation variant 1 gene" [UniProtKB:P50549] synonym: "ER81" EXACT [UniProtKB:P50549] xref: EMBL:AC004857 xref: EMBL:AF109621 xref: EMBL:AF109622 xref: EMBL:AF109623 xref: EMBL:AF109624 xref: EMBL:AF109625 xref: EMBL:AF109626 xref: EMBL:AF109627 xref: EMBL:AF109628 xref: EMBL:AF109629 xref: EMBL:AF109630 xref: EMBL:AF109631 xref: EMBL:AF109632 xref: EMBL:BC098403 xref: EMBL:BC106762 xref: EMBL:BC106763 xref: EMBL:U17163 xref: EMBL:X87175 xref: HGNC:HGNC:3490 xref: UniGene:Hs.22634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055452 ! ETV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017737 name: ETV2_human def: "ETS translocation variant 2 gene" [UniProtKB:O00321] synonym: "ER71" EXACT [UniProtKB:O00321] synonym: "ETSRP71" EXACT [UniProtKB:O00321] xref: EMBL:AC002115 xref: EMBL:AF000671 xref: EMBL:BC107124 xref: HGNC:HGNC:3491 xref: UniGene:Hs.194061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030315 ! ETV2_HUMAN relationship: codes_for CCO:B0030323 ! Q3KNT2_HUMAN relationship: codes_for CCO:B0030326 ! A6NFN5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017738 name: ETV3L_human def: "ETS translocation variant 3-like protein gene" [UniProtKB:Q6ZN32] xref: EMBL:AK131392 xref: HGNC:HGNC:33834 xref: UniGene:Hs.127138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057008 ! ETV3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017739 name: ETV3_human def: "ETS translocation variant 3 gene" [UniProtKB:P41162] synonym: "METS" EXACT [UniProtKB:P41162] synonym: "PE1" EXACT [UniProtKB:P41162] xref: EMBL:AF218540 xref: EMBL:AL157713 xref: EMBL:BC022868 xref: EMBL:L16464 xref: HGNC:HGNC:3492 xref: UniGene:Hs.352672 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030312 ! ETV3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017740 name: ETV4_human def: "ETS translocation variant 4 gene" [UniProtKB:P43268] synonym: "E1AF" EXACT [UniProtKB:P43268] xref: EMBL:AF095887 xref: EMBL:AF095888 xref: EMBL:AF095889 xref: EMBL:AF095890 xref: EMBL:BC016623 xref: EMBL:D12765 xref: EMBL:U18018 xref: HGNC:HGNC:3493 xref: UniGene:Hs.434059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055362 ! ETV4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017741 name: ETV5_human def: "ETS translocation variant 5 gene" [UniProtKB:P41161] synonym: "ERM" EXACT [UniProtKB:P41161] xref: EMBL:AC108671 xref: EMBL:AC112649 xref: EMBL:AC131156 xref: EMBL:BC007333 xref: EMBL:BT006713 xref: EMBL:CH471052 xref: EMBL:CR456767 xref: EMBL:X76184 xref: EMBL:X96375 xref: EMBL:X96376 xref: EMBL:X96377 xref: EMBL:X96378 xref: EMBL:X96379 xref: EMBL:X96380 xref: EMBL:X96381 xref: EMBL:X96382 xref: HGNC:HGNC:3494 xref: UniGene:Hs.43697 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055334 ! ETV5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017742 name: ETV7_human def: "Transcription factor ETV7 gene" [UniProtKB:Q9Y603] synonym: "TEL2" EXACT [UniProtKB:Q9Y603] synonym: "TELB" EXACT [UniProtKB:Q9Y603] synonym: "TREF" EXACT [UniProtKB:Q9Y603] xref: EMBL:AF116508 xref: EMBL:AF116509 xref: EMBL:AF116510 xref: EMBL:AF147782 xref: EMBL:AF175387 xref: EMBL:AF218235 xref: EMBL:AF218365 xref: EMBL:AF218366 xref: EMBL:AJ276205 xref: EMBL:BC035853 xref: EMBL:Z84484 xref: HGNC:HGNC:18160 xref: UniGene:Hs.272398 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059395 ! ETV7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017743 name: EVL_human def: "Ena/VASP-like protein gene" [UniProtKB:Q9UI08] synonym: "RNB6" EXACT [UniProtKB:Q9UI08] xref: EMBL:AF052504 xref: EMBL:AF087843 xref: EMBL:AF112209 xref: EMBL:AF131766 xref: EMBL:AL133642 xref: EMBL:BC023997 xref: EMBL:BC032358 xref: HGNC:HGNC:20234 xref: UniGene:Hs.125867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059153 ! EVL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017744 name: EVX1_human def: "Homeobox even-skipped homolog protein 1 gene" [UniProtKB:P49640] xref: EMBL:AC004080 xref: EMBL:U68781 xref: EMBL:U68782 xref: EMBL:X60655 xref: HGNC:HGNC:3506 xref: UniGene:Hs.369879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055427 ! EVX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017745 name: EVX2_human def: "Homeobox even-skipped homolog protein 2 gene" [UniProtKB:Q03828] xref: EMBL:AC009336 xref: EMBL:M59982 xref: EMBL:M59983 xref: HGNC:HGNC:3507 xref: UniGene:Hs.452341 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055726 ! EVX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017746 name: EYA1_human def: "Eyes absent homolog 1 gene" [UniProtKB:Q99502] xref: EMBL:AC016465 xref: EMBL:AJ000097 xref: EMBL:AJ000098 xref: EMBL:BC121799 xref: EMBL:Y10260 xref: HGNC:HGNC:3519 xref: UniGene:Hs.491997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058419 ! EYA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017747 name: EYA2_human def: "Eyes absent homolog 2 gene" [UniProtKB:O00167] synonym: "EAB1" EXACT [UniProtKB:O00167] xref: EMBL:AJ007992 xref: EMBL:AL049540 xref: EMBL:AL121776 xref: EMBL:AL359434 xref: EMBL:AL390211 xref: EMBL:BC000289 xref: EMBL:BC008803 xref: EMBL:BC013882 xref: EMBL:U71207 xref: EMBL:U81601 xref: EMBL:Y10261 xref: HGNC:HGNC:3520 xref: UniGene:Hs.472877 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054293 ! EYA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017748 name: EYA3_human def: "Eyes absent homolog 3 gene" [UniProtKB:Q99504] xref: EMBL:AJ007991 xref: EMBL:U81602 xref: EMBL:Y10262 xref: HGNC:HGNC:3521 xref: UniGene:Hs.185774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058420 ! EYA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017749 name: EYA4_human def: "Eyes absent homolog 4 gene" [UniProtKB:O95677] xref: EMBL:AJ007993 xref: EMBL:AJ007994 xref: EMBL:AL024497 xref: EMBL:AL121959 xref: EMBL:AL450270 xref: EMBL:BC041063 xref: EMBL:Y17114 xref: EMBL:Y17847 xref: HGNC:HGNC:3522 xref: UniGene:Hs.661127 xref: UniGene:Hs.680507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054782 ! EYA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017750 name: EZH1_human def: "Enhancer of zeste homolog 1 gene" [UniProtKB:Q92800] synonym: "KIAA0388" EXACT [UniProtKB:Q92800] xref: EMBL:AB002386 xref: EMBL:AB004818 xref: EMBL:AC100793 xref: EMBL:BC015882 xref: EMBL:BT009782 xref: EMBL:CH471152 xref: EMBL:L38934 xref: EMBL:U50315 xref: HGNC:HGNC:3526 xref: UniGene:Hs.194669 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058096 ! EZH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017751 name: FAM107A_human def: "Protein FAM107A gene" [UniProtKB:O95990] synonym: "DRR1" EXACT [UniProtKB:O95990] synonym: "TU3A" EXACT [UniProtKB:O95990] xref: EMBL:AB023810 xref: EMBL:AB023811 xref: EMBL:AF089853 xref: EMBL:AF089854 xref: EMBL:AK055443 xref: EMBL:AL050264 xref: EMBL:BC010561 xref: HGNC:HGNC:30827 xref: UniGene:Hs.506357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054816 ! F107A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017752 name: FAM120B_human def: "Constitutive coactivator of peroxisome proliferator-activated receptor gamma gene" [UniProtKB:Q96EK7] synonym: "CCPG" EXACT [UniProtKB:Q96EK7] synonym: "KIAA1838" EXACT [UniProtKB:Q96EK7] xref: EMBL:AB058741 xref: EMBL:AL008628 xref: EMBL:AL078605 xref: EMBL:AY266458 xref: EMBL:BC012177 xref: EMBL:CH471051 xref: EMBL:DQ873695 xref: HGNC:HGNC:21109 xref: UniGene:Hs.369522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058207 ! F120B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017753 name: FAM173A_human def: "Protein FAM173A gene" [UniProtKB:Q9BQD7] synonym: "C16orf24" EXACT [UniProtKB:Q9BQD7] synonym: "RJD7" EXACT [UniProtKB:Q9BQD7] xref: EMBL:AE006464 xref: EMBL:BC001181 xref: EMBL:BC002624 xref: HGNC:HGNC:14152 xref: UniGene:Hs.166244 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061994 ! F173A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017754 name: FABP6_human def: "Gastrotropin gene" [UniProtKB:P51161] synonym: "ILBP" EXACT [UniProtKB:P51161] synonym: "ILLBP" EXACT [UniProtKB:P51161] xref: EMBL:AJ250902 xref: EMBL:BC022489 xref: EMBL:U19869 xref: EMBL:X90908 xref: HGNC:HGNC:3561 xref: UniGene:Hs.519719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055461 ! FABP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017755 name: FADD_human def: "Protein FADD gene" [UniProtKB:Q13158] synonym: "MORT1" EXACT [UniProtKB:Q13158] xref: EMBL:BC000334 xref: EMBL:BT006927 xref: EMBL:U24231 xref: EMBL:X84709 xref: HGNC:HGNC:3573 xref: UniGene:Hs.86131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055881 ! FADD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017756 name: FADS1_human def: "Fatty acid desaturase 1 gene" [UniProtKB:O60427] synonym: "FADSD5" EXACT [UniProtKB:O60427] xref: EMBL:AC004770 xref: EMBL:AF084558 xref: EMBL:AF199596 xref: EMBL:AF226273 xref: EMBL:AK027427 xref: EMBL:AK027522 xref: EMBL:AK074754 xref: EMBL:AK074819 xref: EMBL:AK222906 xref: EMBL:AL512760 xref: EMBL:AL834479 xref: EMBL:BC007846 xref: HGNC:HGNC:3574 xref: UniGene:Hs.503546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054556 ! FADS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017757 name: FAF1_human def: "FAS-associated factor 1 gene" [UniProtKB:Q9UNN5] synonym: "CGI-03" EXACT [UniProtKB:Q9UNN5] synonym: "UBXD12" EXACT [UniProtKB:Q9UNN5] synonym: "UBXN3A" EXACT [UniProtKB:Q9UNN5] xref: EMBL:AF094700 xref: EMBL:AF106798 xref: EMBL:AF132938 xref: EMBL:AJ271408 xref: EMBL:AL133631 xref: EMBL:BC004970 xref: EMBL:BC067100 xref: HGNC:HGNC:3578 xref: UniGene:Hs.530402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059254 ! FAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017758 name: FAIM_human def: "Fas apoptotic inhibitory molecule 1 gene" [UniProtKB:Q9NVQ4] synonym: "FAIM1" EXACT [UniProtKB:Q9NVQ4] xref: EMBL:AK001444 xref: EMBL:AK125477 xref: EMBL:BC012478 xref: EMBL:CR457122 xref: HGNC:HGNC:18703 xref: UniGene:Hs.173438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056757 ! Q6IAN2_HUMAN relationship: codes_for CCO:B0058933 ! FAIM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017759 name: FAIM2_human def: "Fas apoptotic inhibitory molecule 2 gene" [UniProtKB:Q9BWQ8] synonym: "KIAA0950" EXACT [UniProtKB:Q9BWQ8] synonym: "LFG" EXACT [UniProtKB:Q9BWQ8] synonym: "TMBIM2" EXACT [UniProtKB:Q9BWQ8] xref: EMBL:AB023167 xref: EMBL:AF190461 xref: EMBL:BC000051 xref: HGNC:HGNC:17067 xref: UniGene:Hs.567424 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058535 ! FAIM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017760 name: FAIM3_human def: "Fas apoptotic inhibitory molecule 3 precursor gene" [UniProtKB:O60667] synonym: "TOSO" EXACT [UniProtKB:O60667] xref: EMBL:AF057557 xref: EMBL:BC006401 xref: EMBL:BT006797 xref: HGNC:HGNC:14315 xref: UniGene:Hs.58831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054573 ! FAIM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017761 name: FAM3D_human def: "Protein FAM3D precursor gene" [UniProtKB:Q96BQ1] synonym: "UNQ567/PRO1130" EXACT [UniProtKB:Q96BQ1] xref: EMBL:AY358677 xref: EMBL:BC015359 xref: HGNC:HGNC:18665 xref: UniGene:Hs.61265 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058169 ! FAM3D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017762 name: NSMAF_human def: "Protein FAN gene" [UniProtKB:Q92636] synonym: "FAN" EXACT [UniProtKB:Q92636] xref: EMBL:BC041124 xref: EMBL:CH471068 xref: EMBL:X96586 xref: HGNC:HGNC:8017 xref: UniGene:Hs.372000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058077 ! FAN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017763 name: FARP1_human def: "FERM, RhoGEF and pleckstrin domain-containing protein 1 gene" [UniProtKB:Q9Y4F1] synonym: "CDEP" EXACT [UniProtKB:Q9Y4F1] xref: EMBL:AB008430 xref: EMBL:AL136300 xref: EMBL:AL137249 xref: EMBL:AL161896 xref: EMBL:BC041595 xref: EMBL:BC071592 xref: HGNC:HGNC:3591 xref: UniGene:Hs.403917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056492 ! Q5JV91_HUMAN relationship: codes_for CCO:B0056493 ! Q5JV94_HUMAN relationship: codes_for CCO:B0059360 ! FARP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017764 name: FARP2_human def: "FERM, RhoGEF and pleckstrin domain-containing protein 2 gene" [UniProtKB:O94887] synonym: "KIAA0793" EXACT [UniProtKB:O94887] xref: EMBL:AB018336 xref: EMBL:AC005104 xref: EMBL:AC110299 xref: EMBL:AL122052 xref: EMBL:BC021301 xref: HGNC:HGNC:16460 xref: UniGene:Hs.657318 xref: UniGene:Hs.679161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054705 ! FARP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017765 name: FASTK_human def: "Fas-activated serine/threonine kinase gene" [UniProtKB:Q14296] xref: EMBL:BC000377 xref: EMBL:BC011770 xref: EMBL:X86779 xref: HGNC:HGNC:24676 xref: UniGene:Hs.647094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055976 ! FASTK_HUMAN relationship: codes_for CCO:B0062860 ! Q9BWD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017766 name: FIBCD1_human def: "Fibrinogen C domain-containing protein 1 gene" [UniProtKB:Q8N539] synonym: "UNQ701/PRO1346" EXACT [UniProtKB:Q8N539] xref: EMBL:AK027716 xref: EMBL:AL161733 xref: EMBL:AY358311 xref: EMBL:BC032953 xref: HGNC:HGNC:25922 xref: UniGene:Hs.133205 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020113 ! FBCD1_HUMAN relationship: codes_for CCO:B0020121 ! A3KFJ8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017767 name: FBXW4_human def: "F-box/WD repeat-containing protein 4 gene" [UniProtKB:P57775] synonym: "FBW4" EXACT [UniProtKB:P57775] synonym: "SHFM3" EXACT [UniProtKB:P57775] xref: EMBL:AC010789 xref: EMBL:AF281859 xref: EMBL:AL627144 xref: EMBL:AL627424 xref: EMBL:BC007380 xref: EMBL:BC063415 xref: HGNC:HGNC:10847 xref: UniGene:Hs.500822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055562 ! FBXW4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017768 name: FCER1G_human def: "High affinity immunoglobulin epsilon receptor subunit gamma precursor gene" [UniProtKB:P30273] xref: EMBL:AL590714 xref: EMBL:M33195 xref: EMBL:M33196 xref: HGNC:HGNC:3611 xref: UniGene:Hs.433300 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055217 ! FCERG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017769 name: FCGR2B_human def: "Low affinity immunoglobulin gamma Fc region receptor II-b precursor gene" [UniProtKB:P31994] synonym: "CD32" EXACT [UniProtKB:P31994] synonym: "FCG2" EXACT [UniProtKB:P31994] synonym: "IGFR2" EXACT [UniProtKB:P31994] xref: EMBL:AB050934 xref: EMBL:AL359541 xref: EMBL:BC031992 xref: EMBL:CR407635 xref: EMBL:M31933 xref: EMBL:M31934 xref: EMBL:M31935 xref: EMBL:U87560 xref: EMBL:U87561 xref: EMBL:U87562 xref: EMBL:U87563 xref: EMBL:U87564 xref: EMBL:U87565 xref: EMBL:U87566 xref: EMBL:U87567 xref: EMBL:U87568 xref: EMBL:U87569 xref: EMBL:U87570 xref: EMBL:U87571 xref: EMBL:U87572 xref: EMBL:U87573 xref: EMBL:U87574 xref: EMBL:U87575 xref: EMBL:U87576 xref: EMBL:U87577 xref: EMBL:X17653 xref: EMBL:X52473 xref: HGNC:HGNC:3618 xref: UniGene:Hs.654395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055247 ! FCG2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017770 name: FCN1_human def: "Ficolin-1 precursor gene" [UniProtKB:O00602] synonym: "FCNM" EXACT [UniProtKB:O00602] xref: EMBL:BC020635 xref: EMBL:D63394 xref: EMBL:D83920 xref: EMBL:S80990 xref: HGNC:HGNC:3623 xref: UniGene:Hs.440898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020117 ! Q92531_HUMAN relationship: codes_for CCO:B0020122 ! FCN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017771 name: FCN2_human def: "Ficolin-2 precursor gene" [UniProtKB:Q15485] synonym: "FCNL" EXACT [UniProtKB:Q15485] xref: EMBL:AL603650 xref: EMBL:BC069572 xref: EMBL:BC069825 xref: EMBL:CH471090 xref: EMBL:D49353 xref: EMBL:D63160 xref: EMBL:DQ217935 xref: HGNC:HGNC:3624 xref: UniGene:Hs.54517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020112 ! FCN2_HUMAN relationship: codes_for CCO:B0054020 ! A8MT47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017772 name: FCN3_human def: "Ficolin-3 precursor gene" [UniProtKB:O75636] synonym: "FCNH" EXACT [UniProtKB:O75636] synonym: "HAKA1" EXACT [UniProtKB:O75636] xref: EMBL:AK075140 xref: EMBL:AL663123 xref: EMBL:AY756173 xref: EMBL:BC020731 xref: EMBL:CR456808 xref: EMBL:D88587 xref: HGNC:HGNC:3625 xref: UniGene:Hs.333383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054661 ! FCN3_HUMAN relationship: codes_for CCO:B0056536 ! Q5SSB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017773 name: FEM1B_human def: "Protein fem-1 homolog B gene" [UniProtKB:Q9UK73] synonym: "F1AA" EXACT [UniProtKB:Q9UK73] synonym: "KIAA0396" EXACT [UniProtKB:Q9UK73] xref: EMBL:AB007856 xref: EMBL:AF178632 xref: EMBL:AF204883 xref: EMBL:AK290167 xref: EMBL:BC010122 xref: EMBL:BC014558 xref: EMBL:CH471082 xref: HGNC:HGNC:3649 xref: UniGene:Hs.699916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059188 ! FEM1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017774 name: FERD3L_human def: "Fer3-like protein gene" [UniProtKB:Q96RJ6] synonym: "NATO3" EXACT [UniProtKB:Q96RJ6] synonym: "NTWIST" EXACT [UniProtKB:Q96RJ6] xref: EMBL:AF369897 xref: EMBL:AF517122 xref: EMBL:BC069147 xref: EMBL:BC101135 xref: EMBL:BC101136 xref: EMBL:BC101137 xref: EMBL:BC101138 xref: EMBL:CH236948 xref: EMBL:CH471073 xref: HGNC:HGNC:16660 xref: UniGene:Hs.592168 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058380 ! FER3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017775 name: FERMT2_human def: "Fermitin family homolog 2 gene" [UniProtKB:Q96AC1] synonym: "KIND2" EXACT [UniProtKB:Q96AC1] synonym: "MIG2" EXACT [UniProtKB:Q96AC1] synonym: "PLEKHC1" EXACT [UniProtKB:Q96AC1] xref: EMBL:AF443279 xref: EMBL:AL139317 xref: EMBL:AL352979 xref: EMBL:BC011125 xref: EMBL:BC017327 xref: EMBL:BX161467 xref: EMBL:Z24725 xref: HGNC:HGNC:15767 xref: UniGene:Hs.509343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058150 ! FERM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017776 name: FER_human def: "Proto-oncogene tyrosine-protein kinase FER gene" [UniProtKB:P16591] synonym: "TYK3" EXACT [UniProtKB:P16591] xref: EMBL:J03358 xref: HGNC:HGNC:3655 xref: UniGene:Hs.221472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055057 ! FER_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017777 name: FES_human def: "Proto-oncogene tyrosine-protein kinase Fes/Fps gene" [UniProtKB:P07332] synonym: "FPS" EXACT [UniProtKB:P07332] xref: EMBL:BC035357 xref: EMBL:X06292 xref: EMBL:X52192 xref: HGNC:HGNC:3657 xref: UniGene:Hs.7636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054911 ! FES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017778 name: AHSG_human def: "Alpha-2-HS-glycoprotein precursor gene" [UniProtKB:P02765] synonym: "FETUA" EXACT [UniProtKB:P02765] synonym: "PRO2743" EXACT [UniProtKB:P02765] xref: EMBL:AB038689 xref: EMBL:AF119895 xref: EMBL:BC048198 xref: EMBL:BC052590 xref: EMBL:D67012 xref: EMBL:D67013 xref: EMBL:M16961 xref: HGNC:HGNC:349 xref: UniGene:Hs.324746 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054873 ! FETUA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017779 name: FEZF1_human def: "Fez family zinc finger protein 1 gene" [UniProtKB:A0PJY2] synonym: "FEZ" EXACT [UniProtKB:A0PJY2] synonym: "ZNF312B" EXACT [UniProtKB:A0PJY2] xref: EMBL:BC127714 xref: EMBL:BC127715 xref: EMBL:CH236947 xref: HGNC:HGNC:22788 xref: UniGene:Hs.553970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053704 ! FEZF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017780 name: FEZF2_human def: "Fez family zinc finger protein 2 gene" [UniProtKB:Q8TBJ5] synonym: "FEZL" EXACT [UniProtKB:Q8TBJ5] synonym: "FKSG36" EXACT [UniProtKB:Q8TBJ5] synonym: "ZNF312" EXACT [UniProtKB:Q8TBJ5] xref: EMBL:AF332890 xref: EMBL:AK001004 xref: EMBL:BC022464 xref: HGNC:HGNC:13506 xref: UniGene:Hs.241523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057904 ! FEZF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017781 name: FFAR1_human def: "Free fatty acid receptor 1 gene" [UniProtKB:O14842] synonym: "GPR40" EXACT [UniProtKB:O14842] xref: EMBL:AF024687 xref: EMBL:BC095536 xref: EMBL:BC120944 xref: HGNC:HGNC:4498 xref: UniGene:Hs.248127 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054382 ! FFAR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017782 name: FFAR2_human def: "Free fatty acid receptor 2 gene" [UniProtKB:O15552] synonym: "GPR43" EXACT [UniProtKB:O15552] xref: EMBL:AC002511 xref: EMBL:AF024690 xref: EMBL:BC095535 xref: EMBL:BC096198 xref: EMBL:BC096199 xref: EMBL:BC096200 xref: EMBL:BC096201 xref: HGNC:HGNC:4501 xref: UniGene:Hs.248056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054448 ! FFAR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017783 name: FFAR3_human def: "Free fatty acid receptor 3 gene" [UniProtKB:O14843] synonym: "GPR41" EXACT [UniProtKB:O14843] xref: EMBL:AF024688 xref: EMBL:BC035657 xref: EMBL:BC113695 xref: HGNC:HGNC:4499 xref: UniGene:Hs.248055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054383 ! FFAR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017784 name: FGD1_human def: "FYVE, RhoGEF and PH domain-containing protein 1 gene" [UniProtKB:P98174] synonym: "FGDY" EXACT [UniProtKB:P98174] synonym: "ZFYVE3" EXACT [UniProtKB:P98174] xref: EMBL:BC034530 xref: EMBL:CH471154 xref: EMBL:U11690 xref: EMBL:Z85987 xref: HGNC:HGNC:3663 xref: UniGene:Hs.695944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055676 ! FGD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017785 name: FGD2_human def: "FYVE, RhoGEF and PH domain-containing protein 2 gene" [UniProtKB:Q7Z6J4] synonym: "ZFYVE4" EXACT [UniProtKB:Q7Z6J4] xref: EMBL:AK024456 xref: EMBL:AK097230 xref: EMBL:AK131079 xref: EMBL:AL160264 xref: EMBL:BC023645 xref: EMBL:BC053655 xref: EMBL:BC062363 xref: HGNC:HGNC:3664 xref: UniGene:Hs.509664 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057198 ! FGD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017786 name: FGD3_human def: "FYVE, RhoGEF and PH domain-containing protein 3 gene" [UniProtKB:Q5JSP0] synonym: "ZFYVE5" EXACT [UniProtKB:Q5JSP0] xref: EMBL:AL389924 xref: EMBL:AL451065 xref: EMBL:AY211386 xref: EMBL:BC032429 xref: EMBL:BC111054 xref: HGNC:HGNC:16027 xref: UniGene:Hs.411081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056480 ! FGD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017787 name: FGD4_human def: "FYVE, RhoGEF and PH domain-containing protein 4 gene" [UniProtKB:Q96M96] synonym: "FRABP" EXACT [UniProtKB:Q96M96] synonym: "ZFYVE6" EXACT [UniProtKB:Q96M96] xref: EMBL:AK057294 xref: EMBL:AL713762 xref: EMBL:AY367054 xref: EMBL:BC045552 xref: HGNC:HGNC:19125 xref: UniGene:Hs.117835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056300 ! Q49A55_HUMAN relationship: codes_for CCO:B0058282 ! FGD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017788 name: FGD5_human def: "FYVE, RhoGEF and PH domain-containing protein 5 gene" [UniProtKB:Q6ZNL6] synonym: "ZFYVE23" EXACT [UniProtKB:Q6ZNL6] xref: EMBL:AK096856 xref: EMBL:AK097276 xref: EMBL:AK131078 xref: EMBL:BC035364 xref: EMBL:BF989107 xref: EMBL:BX538312 xref: EMBL:BX640820 xref: HGNC:HGNC:19117 xref: UniGene:Hs.412406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057029 ! FGD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017789 name: FGD6_human def: "FYVE, RhoGEF and PH domain-containing protein 6 gene" [UniProtKB:Q6ZV73] synonym: "KIAA1362" EXACT [UniProtKB:Q6ZV73] synonym: "ZFYVE24" EXACT [UniProtKB:Q6ZV73] xref: EMBL:AB037783 xref: EMBL:AK002045 xref: EMBL:AK124904 xref: EMBL:AK128492 xref: EMBL:BC013319 xref: EMBL:BX538322 xref: HGNC:HGNC:21740 xref: UniGene:Hs.506381 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057083 ! FGD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017790 name: FGF11_human def: "Fibroblast growth factor 11 gene" [UniProtKB:Q92914] synonym: "FHF3" EXACT [UniProtKB:Q92914] xref: EMBL:AY049782 xref: EMBL:AY094623 xref: EMBL:BC032502 xref: EMBL:BC108265 xref: EMBL:U66199 xref: HGNC:HGNC:3667 xref: UniGene:Hs.655193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017679 ! FGF11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017791 name: FGF12_human def: "Fibroblast growth factor 12 gene" [UniProtKB:P61328] synonym: "FGF12B" EXACT [UniProtKB:P61328] synonym: "FHF1" EXACT [UniProtKB:P61328] xref: EMBL:BC022524 xref: EMBL:U66197 xref: EMBL:U76381 xref: HGNC:HGNC:3668 xref: UniGene:Hs.584758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017668 ! FGF12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017792 name: FGF13_human def: "Fibroblast growth factor 13 gene" [UniProtKB:Q92913] synonym: "FHF2" EXACT [UniProtKB:Q92913] xref: EMBL:AF100143 xref: EMBL:AF100144 xref: EMBL:AY672645 xref: EMBL:BC012347 xref: EMBL:BC034340 xref: EMBL:U66198 xref: HGNC:HGNC:3670 xref: UniGene:Hs.6540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017676 ! FGF13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017793 name: FGF14_human def: "Fibroblast growth factor 14 gene" [UniProtKB:Q92915] synonym: "FHF4" EXACT [UniProtKB:Q92915] xref: EMBL:AE014303 xref: EMBL:AL160153 xref: EMBL:AL356263 xref: EMBL:AL512629 xref: EMBL:AL591909 xref: EMBL:AY188178 xref: EMBL:BC100920 xref: EMBL:BC100921 xref: EMBL:BC100922 xref: EMBL:U66200 xref: HGNC:HGNC:3671 xref: UniGene:Hs.696392 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017677 ! FGF14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017794 name: FGF16_human def: "Fibroblast growth factor 16 gene" [UniProtKB:O43320] xref: EMBL:AB009391 xref: HGNC:HGNC:3672 xref: UniGene:Hs.666364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017671 ! FGF16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017795 name: FGF17_human def: "Fibroblast growth factor 17 precursor gene" [UniProtKB:O60258] synonym: "UNQ161/PRO187" EXACT [UniProtKB:O60258] xref: EMBL:AB009249 xref: EMBL:AF497475 xref: EMBL:AY358869 xref: EMBL:BC069475 xref: EMBL:BC105131 xref: EMBL:BC113489 xref: HGNC:HGNC:3673 xref: UniGene:Hs.248192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022985 ! FGF17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017796 name: FGF18_human def: "Fibroblast growth factor 18 precursor gene" [UniProtKB:O76093] synonym: "UNQ420/PRO856" EXACT [UniProtKB:O76093] xref: EMBL:AB007422 xref: EMBL:AF075292 xref: EMBL:AF211188 xref: EMBL:AY358811 xref: EMBL:BC006245 xref: EMBL:BT019570 xref: EMBL:BT019571 xref: HGNC:HGNC:3674 xref: UniGene:Hs.87191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022986 ! FGF18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017797 name: FGF20_human def: "Fibroblast growth factor 20 gene" [UniProtKB:Q9NP95] xref: EMBL:AB030648 xref: EMBL:AB044277 xref: EMBL:AY696296 xref: HGNC:HGNC:3677 xref: UniGene:Hs.199905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017509 ! FGF20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017798 name: FGF21_human def: "Fibroblast growth factor 21 precursor gene" [UniProtKB:Q9NSA1] synonym: "UNQ3115/PRO10196" EXACT [UniProtKB:Q9NSA1] xref: EMBL:AB021975 xref: EMBL:AY359086 xref: HGNC:HGNC:3678 xref: UniGene:Hs.283015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058912 ! FGF21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017799 name: FGF22_human def: "Fibroblast growth factor 22 precursor gene" [UniProtKB:Q9HCT0] synonym: "UNQ2500/PRO5800" EXACT [UniProtKB:Q9HCT0] xref: EMBL:AB021925 xref: EMBL:AY359084 xref: EMBL:AY426986 xref: HGNC:HGNC:3679 xref: UniGene:Hs.248087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017511 ! FGF22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017800 name: FGF23_human def: "Fibroblast growth factor 23 precursor gene" [UniProtKB:Q9GZV9] synonym: "HYPF" EXACT [UniProtKB:Q9GZV9] synonym: "UNQ3027/PRO9828" EXACT [UniProtKB:Q9GZV9] xref: EMBL:AB037973 xref: EMBL:AB047858 xref: EMBL:AF263537 xref: EMBL:AY358323 xref: EMBL:AY566236 xref: EMBL:BC069333 xref: EMBL:BC096713 xref: EMBL:BC098147 xref: EMBL:BC098252 xref: HGNC:HGNC:3680 xref: UniGene:Hs.287370 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058640 ! FGF23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017801 name: FGFR4_human def: "Fibroblast growth factor receptor 4 precursor gene" [UniProtKB:P22455] synonym: "JTK2" EXACT [UniProtKB:P22455] synonym: "TKF" EXACT [UniProtKB:P22455] xref: EMBL:AF202063 xref: EMBL:AF487555 xref: EMBL:BC011847 xref: EMBL:CH471195 xref: EMBL:EF571596 xref: EMBL:L03840 xref: EMBL:M59373 xref: EMBL:X57205 xref: EMBL:Y13901 xref: HGNC:HGNC:3691 xref: UniGene:Hs.165950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055147 ! FGFR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017802 name: FGL1_human def: "Fibrinogen-like protein 1 precursor gene" [UniProtKB:Q08830] synonym: "HFREP1" EXACT [UniProtKB:Q08830] xref: EMBL:AC087273 xref: EMBL:BC007047 xref: EMBL:BT006635 xref: EMBL:D14446 xref: EMBL:D87342 xref: EMBL:DQ086826 xref: HGNC:HGNC:3695 xref: UniGene:Hs.491143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055795 ! FGL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017803 name: FGL2_human def: "Fibroleukin precursor gene" [UniProtKB:Q14314] xref: EMBL:AF104014 xref: EMBL:AF104015 xref: EMBL:AF468959 xref: EMBL:BC033820 xref: EMBL:BC073986 xref: EMBL:Z36531 xref: HGNC:HGNC:3696 xref: UniGene:Hs.520989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055977 ! FGL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017804 name: FGFRL1_human def: "Fibroblast growth factor receptor-like 1 precursor gene" [UniProtKB:Q8N441] synonym: "FGFR5" EXACT [UniProtKB:Q8N441] synonym: "FHFR" EXACT [UniProtKB:Q8N441] synonym: "UNQ480/PRO943" EXACT [UniProtKB:Q8N441] xref: EMBL:AF279689 xref: EMBL:AF312678 xref: EMBL:AJ277437 xref: EMBL:AY358303 xref: EMBL:BC013955 xref: EMBL:BC036769 xref: HGNC:HGNC:3693 xref: UniGene:Hs.193326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057462 ! FGRL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017805 name: FGA_human def: "Fibrinogen alpha chain precursor gene" [UniProtKB:P02671] xref: EMBL:AF361104 xref: EMBL:BC020764 xref: EMBL:BC070246 xref: EMBL:BC105803 xref: EMBL:J00127 xref: EMBL:J00128 xref: EMBL:K02272 xref: EMBL:M26878 xref: EMBL:M58569 xref: EMBL:M64982 xref: HGNC:HGNC:3661 xref: UniGene:Hs.351593 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054865 ! FIBA_HUMAN relationship: codes_for CCO:B0056259 ! Q3KRA7_HUMAN relationship: codes_for CCO:B0056850 ! Q6NSD8_HUMAN relationship: codes_for CCO:B0058001 ! Q8WW76_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017806 name: FGB_human def: "Fibrinogen beta chain precursor gene" [UniProtKB:P02675] xref: EMBL:AF388026 xref: EMBL:BC007030 xref: EMBL:BC106760 xref: EMBL:J00129 xref: EMBL:J00130 xref: EMBL:J00131 xref: EMBL:J00132 xref: EMBL:J00133 xref: EMBL:M26876 xref: EMBL:M26877 xref: EMBL:M64983 xref: EMBL:X05018 xref: HGNC:HGNC:3662 xref: UniGene:Hs.300774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053701 ! A0JLR9_HUMAN relationship: codes_for CCO:B0054866 ! FIBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017807 name: FGG_human def: "Fibrinogen gamma chain precursor gene" [UniProtKB:P02679] synonym: "PRO2061" EXACT [UniProtKB:P02679] xref: EMBL:AF118092 xref: EMBL:AF350254 xref: EMBL:BC007044 xref: EMBL:BC021674 xref: EMBL:K02569 xref: EMBL:M10014 xref: EMBL:X00086 xref: EMBL:X51473 xref: HGNC:HGNC:3694 xref: UniGene:Hs.546255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054867 ! FIBG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017808 name: FIGLA_human def: "Factor in the germline alpha gene" [UniProtKB:Q6QHK4] xref: EMBL:AY541030 xref: EMBL:BC039536 xref: HGNC:HGNC:24669 xref: UniGene:Hs.407636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056929 ! FIGLA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017809 name: FIZ1_human def: "Flt3-interacting zinc finger protein 1 gene" [UniProtKB:Q96SL8] synonym: "ZNF798" EXACT [UniProtKB:Q96SL8] xref: EMBL:AK027674 xref: EMBL:AK160385 xref: HGNC:HGNC:25917 xref: UniGene:Hs.515617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058392 ! FIZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017810 name: FKBP8_human def: "FK506-binding protein 8 gene" [UniProtKB:Q14318] synonym: "FKBP38" EXACT [UniProtKB:Q14318] xref: EMBL:AC005387 xref: EMBL:AK222838 xref: EMBL:AY225339 xref: EMBL:AY278607 xref: EMBL:BC009966 xref: EMBL:BX538124 xref: EMBL:CH471106 xref: EMBL:L37033 xref: HGNC:HGNC:3724 xref: UniGene:Hs.173464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055978 ! FKBP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017811 name: FLI1_human def: "Friend leukemia integration 1 transcription factor gene" [UniProtKB:Q01543] xref: EMBL:AY029368 xref: EMBL:BC001670 xref: EMBL:BC010115 xref: EMBL:D38408 xref: EMBL:M93255 xref: EMBL:M98833 xref: EMBL:S45205 xref: EMBL:X67001 xref: EMBL:Y17293 xref: HGNC:HGNC:3749 xref: UniGene:Hs.504281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055690 ! FLI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017812 name: FLII_human def: "Protein flightless-1 homolog gene" [UniProtKB:Q13045] synonym: "FLIL" EXACT [UniProtKB:Q13045] xref: EMBL:BC025300 xref: EMBL:U01184 xref: EMBL:U80184 xref: HGNC:HGNC:3750 xref: UniGene:Hs.513984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055869 ! FLII_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017813 name: FLT3LG_human def: "SL cytokine precursor gene" [UniProtKB:P49771] xref: EMBL:BC126293 xref: EMBL:U03858 xref: EMBL:U04806 xref: EMBL:U29874 xref: HGNC:HGNC:3766 xref: UniGene:Hs.428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055435 ! FLT3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017814 name: FMNL2_human def: "Formin-like protein 2 gene" [UniProtKB:Q96PY5] synonym: "FHOD2" EXACT [UniProtKB:Q96PY5] synonym: "KIAA1902" EXACT [UniProtKB:Q96PY5] xref: EMBL:AB067489 xref: EMBL:AL834396 xref: EMBL:BC113878 xref: EMBL:BC114438 xref: HGNC:HGNC:18267 xref: UniGene:Hs.654630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058348 ! FMNL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017815 name: FMOD_human def: "Fibromodulin precursor gene" [UniProtKB:Q06828] synonym: "FM" EXACT [UniProtKB:Q06828] synonym: "SLRR2E" EXACT [UniProtKB:Q06828] xref: EMBL:X72913 xref: EMBL:X75546 xref: HGNC:HGNC:3774 xref: UniGene:Hs.519168 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055774 ! FMOD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017816 name: SRGAP2_human def: "SLIT-ROBO Rho GTPase-activating protein 2 gene" [UniProtKB:O75044] synonym: "FNBP2" EXACT [UniProtKB:O75044] synonym: "KIAA0456" EXACT [UniProtKB:O75044] xref: EMBL:AB007925 xref: EMBL:AL161736 xref: HGNC:HGNC:19751 xref: UniGene:Hs.497575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054598 ! FNBP2_HUMAN relationship: codes_for CCO:B0056673 ! Q5VZB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017817 name: FNTA_human def: "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha gene" [UniProtKB:P49354] xref: EMBL:BC017029 xref: EMBL:BC084566 xref: EMBL:L00634 xref: EMBL:L10413 xref: HGNC:HGNC:3782 xref: UniGene:Hs.370312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055421 ! FNTA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017818 name: ZFPM1_human def: "Zinc finger protein ZFPM1 gene" [UniProtKB:Q8IX07] synonym: "FOG1" EXACT [UniProtKB:Q8IX07] xref: EMBL:AF488691 xref: HGNC:HGNC:19762 xref: UniGene:Hs.632218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057367 ! FOG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017819 name: ZFPM2_human def: "Zinc finger protein ZFPM2 gene" [UniProtKB:Q8WW38] synonym: "FOG2" EXACT [UniProtKB:Q8WW38] xref: EMBL:AF119334 xref: EMBL:AL389987 xref: EMBL:AL389989 xref: EMBL:BC020928 xref: EMBL:BC109222 xref: HGNC:HGNC:16700 xref: UniGene:Hs.431009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057999 ! FOG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017820 name: FOSL2_human def: "Fos-related antigen 2 gene" [UniProtKB:P15408] synonym: "FRA2" EXACT [UniProtKB:P15408] xref: EMBL:AC104695 xref: EMBL:BC022791 xref: EMBL:CH471053 xref: EMBL:X16706 xref: HGNC:HGNC:3798 xref: UniGene:Hs.220971 xref: UniGene:Hs.596972 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053826 ! A6NG20_HUMAN relationship: codes_for CCO:B0055036 ! FOSL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017821 name: FOS_human def: "Proto-oncogene protein c-fos gene" [UniProtKB:P01100] synonym: "G0S7" EXACT [UniProtKB:P01100] xref: EMBL:AF111167 xref: EMBL:AY212879 xref: EMBL:BC004490 xref: EMBL:K00650 xref: EMBL:S65138 xref: EMBL:V01512 xref: HGNC:HGNC:3796 xref: UniGene:Hs.25647 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054833 ! FOS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017822 name: FOXH1_human def: "Forkhead box protein H1 gene" [UniProtKB:O75593] synonym: "FAST1" EXACT [UniProtKB:O75593] synonym: "FAST2" EXACT [UniProtKB:O75593] xref: EMBL:AF076292 xref: EMBL:BC065377 xref: HGNC:HGNC:3814 xref: UniGene:Hs.705796 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054655 ! FOXH1_HUMAN relationship: codes_for CCO:B0056877 ! Q6P0Y2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017823 name: FOXM1_human def: "Forkhead box protein M1 gene" [UniProtKB:Q08050] synonym: "FKHL16" EXACT [UniProtKB:Q08050] synonym: "HFH11" EXACT [UniProtKB:Q08050] synonym: "MPP2" EXACT [UniProtKB:Q08050] synonym: "WIN" EXACT [UniProtKB:Q08050] xref: EMBL:BC006192 xref: EMBL:BC006529 xref: EMBL:BC012863 xref: EMBL:DQ022289 xref: EMBL:L16783 xref: EMBL:U74612 xref: EMBL:U74613 xref: EMBL:U83113 xref: HGNC:HGNC:3818 xref: UniGene:Hs.239 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055788 ! FOXM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017824 name: FOXN1_human def: "Forkhead box protein N1 gene" [UniProtKB:O15353] synonym: "RONU" EXACT [UniProtKB:O15353] synonym: "WHN" EXACT [UniProtKB:O15353] xref: EMBL:Y11739 xref: EMBL:Y11741 xref: EMBL:Y11742 xref: EMBL:Y11743 xref: EMBL:Y11744 xref: EMBL:Y11745 xref: EMBL:Y11746 xref: HGNC:HGNC:12765 xref: UniGene:Hs.663679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054431 ! FOXN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017825 name: FOXN4_human def: "Forkhead box protein N4 gene" [UniProtKB:Q96NZ1] xref: EMBL:AC012384 xref: EMBL:AF425596 xref: EMBL:AF425597 xref: EMBL:AK131519 xref: HGNC:HGNC:21399 xref: UniGene:Hs.528316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058315 ! FOXN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017826 name: FOXP3_human def: "Forkhead box protein P3 gene" [UniProtKB:Q9BZS1] synonym: "IPEX" EXACT [UniProtKB:Q9BZS1] synonym: "JM2" EXACT [UniProtKB:Q9BZS1] xref: EMBL:AF235097 xref: EMBL:AF277993 xref: EMBL:AJ005891 xref: EMBL:BC113401 xref: EMBL:BC113403 xref: EMBL:DQ010327 xref: HGNC:HGNC:6106 xref: UniGene:Hs.247700 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058606 ! FOXP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017827 name: FOXR1_human def: "Forkhead box protein R1 gene" [UniProtKB:Q6PIV2] synonym: "DLNB13" EXACT [UniProtKB:Q6PIV2] synonym: "FOXN5" EXACT [UniProtKB:Q6PIV2] xref: EMBL:AB094092 xref: EMBL:BC028191 xref: EMBL:BC038969 xref: HGNC:HGNC:29980 xref: UniGene:Hs.116679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056915 ! FOXR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017828 name: FOXR2_human def: "Forkhead box protein R2 gene" [UniProtKB:Q6PJQ5] synonym: "FOXN6" EXACT [UniProtKB:Q6PJQ5] xref: EMBL:BC012934 xref: HGNC:HGNC:30469 xref: UniGene:Hs.364260 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056922 ! FOXR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017829 name: FPR2_human def: "N-formyl peptide receptor 2 gene" [UniProtKB:P25090] synonym: "FPRH1" EXACT [UniProtKB:P25090] synonym: "FPRL1" EXACT [UniProtKB:P25090] synonym: "LXA4R" EXACT [UniProtKB:P25090] xref: EMBL:AC018755 xref: EMBL:AF054013 xref: EMBL:AY225226 xref: EMBL:BC029125 xref: EMBL:BC071722 xref: EMBL:D10922 xref: EMBL:M76672 xref: EMBL:M84562 xref: EMBL:M88107 xref: EMBL:U81501 xref: EMBL:X63819 xref: HGNC:HGNC:3827 xref: UniGene:Hs.99855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055179 ! FPR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017830 name: FPR3_human def: "N-formyl peptide receptor 3 gene" [UniProtKB:P25089] synonym: "FPRH1" EXACT [UniProtKB:P25089] synonym: "FPRL2" EXACT [UniProtKB:P25089] xref: EMBL:AY262690 xref: EMBL:BC059388 xref: EMBL:BC069070 xref: EMBL:BC069593 xref: EMBL:BC069812 xref: EMBL:L14061 xref: EMBL:M76673 xref: HGNC:HGNC:3828 xref: UniGene:Hs.445466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055178 ! FPR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017831 name: FGFR1OP_human def: "FGFR1 oncogene partner gene" [UniProtKB:O95684] synonym: "FOP" EXACT [UniProtKB:O95684] xref: EMBL:BC011902 xref: EMBL:BC037785 xref: EMBL:Y18046 xref: EMBL:Z94721 xref: HGNC:HGNC:17012 xref: UniGene:Hs.487175 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054783 ! FR1OP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017832 name: FRAT1_human def: "Proto-oncogene FRAT1 gene" [UniProtKB:Q92837] xref: EMBL:AB074890 xref: EMBL:AL355490 xref: EMBL:BC034476 xref: EMBL:U58975 xref: HGNC:HGNC:3944 xref: UniGene:Hs.126057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058101 ! FRAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017833 name: FRAT2_human def: "GSK-3-binding protein FRAT2 gene" [UniProtKB:O75474] xref: EMBL:AB045118 xref: EMBL:AF062739 xref: EMBL:AL355490 xref: EMBL:BC020165 xref: HGNC:HGNC:16048 xref: UniGene:Hs.140720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054641 ! FRAT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017834 name: FRS2_human def: "Fibroblast growth factor receptor substrate 2 gene" [UniProtKB:Q8WU20] xref: EMBL:AC018921 xref: EMBL:AF036717 xref: EMBL:AK312477 xref: EMBL:BC021562 xref: EMBL:CH471054 xref: EMBL:EU332842 xref: HGNC:HGNC:16971 xref: UniGene:Hs.593446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057975 ! FRS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017835 name: FRS3_human def: "Fibroblast growth factor receptor substrate 3 gene" [UniProtKB:O43559] xref: EMBL:AF036718 xref: EMBL:AL365205 xref: EMBL:BC010611 xref: EMBL:CR457026 xref: HGNC:HGNC:16970 xref: UniGene:Hs.194208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054491 ! FRS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017836 name: FRYL_human def: "Protein furry homolog-like gene" [UniProtKB:O94915] synonym: "AF4P12" EXACT [UniProtKB:O94915] synonym: "KIAA0826" EXACT [UniProtKB:O94915] xref: EMBL:AB020633 xref: EMBL:AC068037 xref: EMBL:AC096952 xref: EMBL:AL137546 xref: EMBL:BC021803 xref: EMBL:U80082 xref: HGNC:HGNC:29127 xref: UniGene:Hs.631525 xref: UniGene:Hs.646327 xref: UniGene:Hs.705749 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054711 ! FRYL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017837 name: FRY_human def: "Protein furry homolog gene" [UniProtKB:Q5TBA9] synonym: "C13orf14" EXACT [UniProtKB:Q5TBA9] xref: EMBL:AL049784 xref: EMBL:AL137143 xref: EMBL:AL138692 xref: EMBL:AL445212 xref: HGNC:HGNC:20367 xref: UniGene:Hs.507669 xref: UniGene:Hs.591225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056605 ! FRY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017838 name: FSBP_human def: "Fibrinogen silencer-binding protein gene" [UniProtKB:O95073] xref: EMBL:AF007866 xref: EMBL:AF487652 xref: EMBL:BC033710 xref: UniGene:Hs.30561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054720 ! FSBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017839 name: FSCN1_human def: "Fascin gene" [UniProtKB:Q16658] synonym: "FAN1" EXACT [UniProtKB:Q16658] synonym: "HSN" EXACT [UniProtKB:Q16658] synonym: "SNL" EXACT [UniProtKB:Q16658] xref: EMBL:AC006483 xref: EMBL:AY044229 xref: EMBL:BC000521 xref: EMBL:BC006304 xref: EMBL:BC007643 xref: EMBL:BC007948 xref: EMBL:BC007988 xref: EMBL:BT006636 xref: EMBL:CH471144 xref: EMBL:U03057 xref: EMBL:U09873 xref: HGNC:HGNC:11148 xref: UniGene:Hs.118400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056170 ! FSCN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017840 name: FSHB_human def: "Follitropin subunit beta precursor gene" [UniProtKB:P01225] xref: EMBL:AL358944 xref: EMBL:BC113488 xref: EMBL:BC113490 xref: EMBL:M16646 xref: EMBL:M16647 xref: EMBL:M24539 xref: EMBL:M24540 xref: EMBL:M54913 xref: EMBL:M54914 xref: HGNC:HGNC:3964 xref: UniGene:Hs.36975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054839 ! FSHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017841 name: FSTL1_human def: "Follistatin-related protein 1 precursor gene" [UniProtKB:Q12841] synonym: "FRP" EXACT [UniProtKB:Q12841] xref: EMBL:AB119283 xref: EMBL:AK289388 xref: EMBL:AK312261 xref: EMBL:BC000055 xref: EMBL:CH471052 xref: EMBL:D89937 xref: EMBL:U06863 xref: HGNC:HGNC:3972 xref: UniGene:Hs.269512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055848 ! FSTL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017842 name: FSTL3_human def: "Follistatin-related protein 3 precursor gene" [UniProtKB:O95633] synonym: "FLRG" EXACT [UniProtKB:O95633] synonym: "UNQ674/PRO1308" EXACT [UniProtKB:O95633] xref: EMBL:AY358917 xref: EMBL:BC005839 xref: EMBL:BC033119 xref: EMBL:U76702 xref: HGNC:HGNC:3973 xref: UniGene:Hs.529038 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054778 ! FSTL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017843 name: FST_human def: "Follistatin precursor gene" [UniProtKB:P19883] xref: EMBL:BC004107 xref: EMBL:M19480 xref: EMBL:M19481 xref: HGNC:HGNC:3971 xref: UniGene:Hs.9914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055111 ! FST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017844 name: FUBP1_human def: "Far upstream element-binding protein 1 gene" [UniProtKB:Q96AE4] xref: EMBL:BC017247 xref: EMBL:U05040 xref: HGNC:HGNC:4004 xref: UniGene:Hs.567380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058151 ! FUBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017845 name: KHSRP_human def: "Far upstream element-binding protein 2 gene" [UniProtKB:Q92945] synonym: "FUBP2" EXACT [UniProtKB:Q92945] xref: EMBL:AB209662 xref: EMBL:AF093745 xref: EMBL:AF093747 xref: EMBL:AF093748 xref: EMBL:BC085004 xref: EMBL:U69126 xref: EMBL:U94832 xref: HGNC:HGNC:6316 xref: UniGene:Hs.699378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058114 ! FUBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017846 name: FUBP3_human def: "Far upstream element-binding protein 3 gene" [UniProtKB:Q96I24] synonym: "FBP3" EXACT [UniProtKB:Q96I24] xref: EMBL:BC001325 xref: EMBL:BC007874 xref: EMBL:U69127 xref: HGNC:HGNC:4005 xref: UniGene:Hs.673029 xref: UniGene:Hs.98751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058224 ! FUBP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017847 name: FURIN_human def: "Furin precursor gene" [UniProtKB:P09958] synonym: "FUR" EXACT [UniProtKB:P09958] synonym: "PACE" EXACT [UniProtKB:P09958] synonym: "PCSK3" EXACT [UniProtKB:P09958] xref: EMBL:BC012181 xref: EMBL:X04329 xref: EMBL:X15723 xref: EMBL:X17094 xref: HGNC:HGNC:8568 xref: UniGene:Hs.513153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023793 ! FURIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017848 name: FUSIP1_human def: "FUS-interacting serine-arginine-rich protein 1 gene" [UniProtKB:O75494] synonym: "FUSIP2" EXACT [UniProtKB:O75494] synonym: "TASR" EXACT [UniProtKB:O75494] xref: EMBL:AF047448 xref: EMBL:AF067730 xref: EMBL:AF419331 xref: EMBL:AF419332 xref: EMBL:AF449427 xref: EMBL:AK001286 xref: EMBL:AL590609 xref: EMBL:AY048592 xref: EMBL:AY150180 xref: EMBL:AY150181 xref: EMBL:BC001107 xref: EMBL:BC005039 xref: EMBL:BC010074 xref: HGNC:HGNC:16713 xref: UniGene:Hs.3530 xref: UniGene:Hs.652334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030784 ! FUSIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017849 name: FXYD5_human def: "FXYD domain-containing ion transport regulator 5 precursor gene" [UniProtKB:Q96DB9] synonym: "DYSAD" EXACT [UniProtKB:Q96DB9] synonym: "HSPC113" EXACT [UniProtKB:Q96DB9] synonym: "IWU1" EXACT [UniProtKB:Q96DB9] synonym: "UNQ2561/PRO6241" EXACT [UniProtKB:Q96DB9] xref: EMBL:AB072911 xref: EMBL:AC002390 xref: EMBL:AC020907 xref: EMBL:AF161462 xref: EMBL:AF177940 xref: EMBL:AY358991 xref: EMBL:BC009642 xref: EMBL:BT007343 xref: HGNC:HGNC:4029 xref: UniGene:Hs.333418 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058192 ! FXYD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017850 name: FYB_human def: "FYN-binding protein gene" [UniProtKB:O15117] synonym: "SLAP130" EXACT [UniProtKB:O15117] xref: EMBL:AF001862 xref: EMBL:U93049 xref: HGNC:HGNC:4036 xref: UniGene:Hs.370503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054407 ! FYB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017851 name: PIP5K3_human def: "FYVE finger-containing phosphoinositide kinase gene" [UniProtKB:Q9Y2I7] synonym: "KIAA0981" EXACT [UniProtKB:Q9Y2I7] synonym: "PIKFYVE" EXACT [UniProtKB:Q9Y2I7] xref: EMBL:AB023198 xref: EMBL:AK091482 xref: EMBL:AY457063 xref: EMBL:BC032389 xref: EMBL:BC125052 xref: EMBL:BC125053 xref: EMBL:CH471063 xref: HGNC:HGNC:23785 xref: UniGene:Hs.173939 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055801 ! Q08AR7_HUMAN relationship: codes_for CCO:B0055802 ! Q08AR8_HUMAN relationship: codes_for CCO:B0057472 ! Q8N5H0_HUMAN relationship: codes_for CCO:B0059307 ! FYV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017852 name: FZD3_human def: "Frizzled-3 precursor gene" [UniProtKB:Q9NPG1] xref: EMBL:AB039723 xref: EMBL:AJ272427 xref: EMBL:AY005130 xref: HGNC:HGNC:4041 xref: UniGene:Hs.40735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058851 ! FZD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017853 name: FZD4_human def: "Frizzled-4 precursor gene" [UniProtKB:Q9ULV1] xref: EMBL:AB032417 xref: EMBL:AY462097 xref: EMBL:BC114527 xref: EMBL:BC114622 xref: HGNC:HGNC:4042 xref: UniGene:Hs.591968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059233 ! FZD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017854 name: FZD6_human def: "Frizzled-6 precursor gene" [UniProtKB:O60353] xref: EMBL:AB012911 xref: EMBL:AB065702 xref: EMBL:AF072873 xref: EMBL:AF363578 xref: EMBL:BC060836 xref: EMBL:CH471060 xref: HGNC:HGNC:4044 xref: UniGene:Hs.591863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054549 ! FZD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017855 name: GPR109A_human def: "Nicotinic acid receptor 1 gene" [UniProtKB:Q8TDS4] synonym: "HM74A" EXACT [UniProtKB:Q8TDS4] xref: EMBL:AB065876 xref: EMBL:AB083632 xref: EMBL:AY148884 xref: EMBL:BC027965 xref: EMBL:BC056419 xref: EMBL:EU012026 xref: HGNC:HGNC:24827 xref: UniGene:Hs.524812 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057932 ! G109A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017856 name: GPR109B_human def: "Nicotinic acid receptor 2 gene" [UniProtKB:P49019] xref: EMBL:AB065865 xref: EMBL:AK290930 xref: EMBL:BC047891 xref: EMBL:D10923 xref: EMBL:EU293604 xref: HGNC:HGNC:16824 xref: UniGene:Hs.458425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055414 ! G109B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017857 name: GAPDHS_human def: "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific gene" [UniProtKB:O14556] synonym: "GAPD2" EXACT [UniProtKB:O14556] synonym: "GAPDH2" EXACT [UniProtKB:O14556] synonym: "GAPDS" EXACT [UniProtKB:O14556] synonym: "HSD-35" EXACT [UniProtKB:O14556] synonym: "HSD35" EXACT [UniProtKB:O14556] xref: EMBL:AC002389 xref: EMBL:AF216631 xref: EMBL:AF216632 xref: EMBL:AF216633 xref: EMBL:AF216634 xref: EMBL:AF216635 xref: EMBL:AF216636 xref: EMBL:AF216637 xref: EMBL:AF216638 xref: EMBL:AF216639 xref: EMBL:AF216640 xref: EMBL:AF216641 xref: EMBL:AJ005371 xref: EMBL:AY306129 xref: EMBL:BC036373 xref: HGNC:HGNC:24864 xref: UniGene:Hs.248017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054351 ! G3PT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017858 name: GAB1_human def: "GRB2-associated-binding protein 1 gene" [UniProtKB:Q13480] xref: EMBL:AC097658 xref: EMBL:AC104685 xref: EMBL:BC064848 xref: EMBL:DQ021880 xref: EMBL:U43885 xref: HGNC:HGNC:4066 xref: UniGene:Hs.618456 xref: UniGene:Hs.80720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055914 ! GAB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017859 name: GAL_human def: "Galanin precursor gene" [UniProtKB:P22466] synonym: "GAL1" EXACT [UniProtKB:P22466] synonym: "GALN" EXACT [UniProtKB:P22466] synonym: "GLNN" EXACT [UniProtKB:P22466] xref: EMBL:BC030241 xref: EMBL:L11144 xref: EMBL:M77140 xref: HGNC:HGNC:4114 xref: UniGene:Hs.278959 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055148 ! GALA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017860 name: GALP_human def: "Galanin-like peptide precursor gene" [UniProtKB:Q9UBC7] xref: EMBL:AF188492 xref: EMBL:AF188493 xref: EMBL:AY329637 xref: HGNC:HGNC:24840 xref: UniGene:Hs.283915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059066 ! GALP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017861 name: GALR1_human def: "Galanin receptor type 1 gene" [UniProtKB:P47211] synonym: "GALNR" EXACT [UniProtKB:P47211] synonym: "GALNR1" EXACT [UniProtKB:P47211] xref: EMBL:AY541036 xref: EMBL:BC095530 xref: EMBL:CH471117 xref: EMBL:L34339 xref: EMBL:U23854 xref: EMBL:U53511 xref: EMBL:U90658 xref: EMBL:U90659 xref: EMBL:U90660 xref: HGNC:HGNC:4132 xref: UniGene:Hs.272191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055382 ! GALR1_HUMAN relationship: codes_for CCO:B0056330 ! Q4VBL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017862 name: GALR2_human def: "Galanin receptor type 2 gene" [UniProtKB:O43603] synonym: "GALNR2" EXACT [UniProtKB:O43603] xref: EMBL:AF040630 xref: EMBL:AF042782 xref: EMBL:AF058762 xref: EMBL:AF080586 xref: EMBL:BC069130 xref: EMBL:BC074914 xref: EMBL:BC074915 xref: EMBL:BC109051 xref: EMBL:BC109052 xref: HGNC:HGNC:4133 xref: UniGene:Hs.666366 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054498 ! GALR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017863 name: GALR3_human def: "Galanin receptor type 3 gene" [UniProtKB:O60755] synonym: "GALNR3" EXACT [UniProtKB:O60755] xref: EMBL:AB065934 xref: EMBL:AF067733 xref: EMBL:AF073799 xref: EMBL:AF129513 xref: EMBL:AF129514 xref: EMBL:Z97630 xref: HGNC:HGNC:4134 xref: UniGene:Hs.158353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054576 ! GALR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017864 name: GAPVD1_human def: "GTPase-activating protein and VPS9 domain-containing protein 1 gene" [UniProtKB:Q14C86] synonym: "GAPEX5" EXACT [UniProtKB:Q14C86] synonym: "KIAA1521" EXACT [UniProtKB:Q14C86] synonym: "RAP6" EXACT [UniProtKB:Q14C86] xref: EMBL:AB040954 xref: EMBL:AK000126 xref: EMBL:AL080196 xref: EMBL:AL354710 xref: EMBL:AL627223 xref: EMBL:AL834325 xref: EMBL:BC013635 xref: EMBL:BC021119 xref: EMBL:BC114937 xref: EMBL:BC114962 xref: EMBL:CH471090 xref: EMBL:DQ233254 xref: HGNC:HGNC:23375 xref: UniGene:Hs.495134 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054179 ! B0QZ65_HUMAN relationship: codes_for CCO:B0054180 ! B0QZ66_HUMAN relationship: codes_for CCO:B0054181 ! B0QZ67_HUMAN relationship: codes_for CCO:B0056032 ! GAPD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017865 name: GARNL3_human def: "GTPase-activating Rap/Ran-GAP domain-like protein 3 gene" [UniProtKB:Q5VVW2] xref: EMBL:AK095679 xref: EMBL:AL136573 xref: EMBL:AL445222 xref: EMBL:AL450263 xref: EMBL:AL834149 xref: EMBL:BC034983 xref: HGNC:HGNC:25425 xref: UniGene:Hs.29304 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056475 ! Q5JS19_HUMAN relationship: codes_for CCO:B0056661 ! GARL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017866 name: GAS8_human def: "Growth arrest-specific protein 8 gene" [UniProtKB:O95995] synonym: "GAS11" EXACT [UniProtKB:O95995] xref: EMBL:AF050068 xref: EMBL:AF050069 xref: EMBL:AF050070 xref: EMBL:AF050071 xref: EMBL:AF050072 xref: EMBL:AF050073 xref: EMBL:AF050074 xref: EMBL:AF050075 xref: EMBL:AF050076 xref: EMBL:AF050077 xref: EMBL:AF050078 xref: EMBL:AF050079 xref: EMBL:BC104785 xref: EMBL:BC112121 xref: HGNC:HGNC:4166 xref: UniGene:Hs.431792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054817 ! GAS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017867 name: CCKBR_human def: "Gastrin/cholecystokinin type B receptor gene" [UniProtKB:P32239] synonym: "CCKRB" EXACT [UniProtKB:P32239] xref: EMBL:AF074029 xref: EMBL:AF074035 xref: EMBL:AF239668 xref: EMBL:AF441129 xref: EMBL:AK292064 xref: EMBL:AY029770 xref: EMBL:AY322551 xref: EMBL:BC000740 xref: EMBL:BT006789 xref: EMBL:D13305 xref: EMBL:D21219 xref: EMBL:L04473 xref: EMBL:L07746 xref: EMBL:L08112 xref: EMBL:L10822 xref: EMBL:S70057 xref: HGNC:HGNC:1571 xref: UniGene:Hs.203 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055252 ! GASR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017868 name: GAST_human def: "Gastrin precursor gene" [UniProtKB:P01350] synonym: "GAS" EXACT [UniProtKB:P01350] xref: EMBL:BC069724 xref: EMBL:BC069762 xref: EMBL:K01254 xref: EMBL:M15958 xref: EMBL:V00511 xref: EMBL:X00183 xref: HGNC:HGNC:4164 xref: UniGene:Hs.2681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054854 ! GAST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017869 name: GATA1_human def: "Erythroid transcription factor gene" [UniProtKB:P15976] synonym: "ERYF1" EXACT [UniProtKB:P15976] synonym: "GF1" EXACT [UniProtKB:P15976] xref: EMBL:AF196971 xref: EMBL:BC009797 xref: EMBL:M30601 xref: EMBL:X17254 xref: HGNC:HGNC:4170 xref: UniGene:Hs.765 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055045 ! GATA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017870 name: GATA2_human def: "Endothelial transcription factor GATA-2 gene" [UniProtKB:P23769] xref: EMBL:BC002557 xref: EMBL:BC015577 xref: EMBL:BC018988 xref: EMBL:BC051272 xref: EMBL:CH471052 xref: EMBL:M68891 xref: EMBL:M77810 xref: HGNC:HGNC:4171 xref: UniGene:Hs.367725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055165 ! GATA2_HUMAN relationship: codes_for CCO:B0058163 ! Q96BH8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017871 name: GATA3_human def: "Trans-acting T-cell-specific transcription factor GATA-3 gene" [UniProtKB:P23771] xref: EMBL:AY497006 xref: EMBL:BC003070 xref: EMBL:BC006793 xref: EMBL:M69106 xref: EMBL:X55037 xref: EMBL:X55122 xref: EMBL:X58072 xref: HGNC:HGNC:4172 xref: UniGene:Hs.524134 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055166 ! GATA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017872 name: GATA4_human def: "Transcription factor GATA-4 gene" [UniProtKB:P43694] xref: EMBL:BC101580 xref: EMBL:BC105108 xref: EMBL:L34357 xref: HGNC:HGNC:4173 xref: UniGene:Hs.243987 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055369 ! GATA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017873 name: GATA5_human def: "Transcription factor GATA-5 gene" [UniProtKB:Q9BWX5] xref: EMBL:AL499627 xref: EMBL:BC117356 xref: EMBL:BC117358 xref: HGNC:HGNC:15802 xref: UniGene:Hs.352250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058543 ! GATA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017874 name: GATC_human def: "GatC-like protein gene" [UniProtKB:O43716] synonym: "15E1.2" EXACT [UniProtKB:O43716] xref: EMBL:AL021546 xref: EMBL:BC107145 xref: EMBL:BC107146 xref: HGNC:HGNC:25068 xref: UniGene:Hs.369624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054513 ! GATCL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017875 name: GATAD1_human def: "GATA zinc finger domain-containing protein 1 gene" [UniProtKB:Q8WUU5] synonym: "ODAG" EXACT [UniProtKB:Q8WUU5] xref: EMBL:AC000064 xref: EMBL:AK026142 xref: EMBL:BC019350 xref: EMBL:BC031091 xref: EMBL:CH236949 xref: HGNC:HGNC:29941 xref: UniGene:Hs.21145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057984 ! GATD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017876 name: GNB1_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 gene" [UniProtKB:P62873] xref: EMBL:AF501882 xref: EMBL:AL031282 xref: EMBL:AL109917 xref: EMBL:BC004186 xref: EMBL:BC005888 xref: EMBL:BC008991 xref: EMBL:BT007305 xref: EMBL:CH471183 xref: EMBL:CR456784 xref: EMBL:M36430 xref: EMBL:X04526 xref: HGNC:HGNC:4396 xref: UniGene:Hs.430425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055621 ! GBB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017877 name: GNB2_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 gene" [UniProtKB:P62879] xref: EMBL:AF053356 xref: EMBL:AF501883 xref: EMBL:BC010073 xref: EMBL:BC012348 xref: EMBL:BC068003 xref: EMBL:M16514 xref: EMBL:M16538 xref: EMBL:M36429 xref: HGNC:HGNC:4398 xref: UniGene:Hs.185172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055623 ! GBB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017878 name: GNB3_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 gene" [UniProtKB:P16520] xref: EMBL:AF501884 xref: EMBL:AY631872 xref: EMBL:BC000115 xref: EMBL:BC002454 xref: EMBL:BT009800 xref: EMBL:M31328 xref: EMBL:U47924 xref: EMBL:U47930 xref: EMBL:Y12050 xref: EMBL:Y12051 xref: EMBL:Y12052 xref: EMBL:Y12053 xref: EMBL:Y12054 xref: EMBL:Y12055 xref: EMBL:Y12056 xref: EMBL:Y12057 xref: EMBL:Y12058 xref: HGNC:HGNC:4400 xref: UniGene:Hs.631657 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055056 ! GBB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017879 name: GNB4_human def: "Guanine nucleotide-binding protein subunit beta-4 gene" [UniProtKB:Q9HAV0] xref: EMBL:AF300648 xref: EMBL:BC000873 xref: HGNC:HGNC:20731 xref: UniGene:Hs.173030 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058769 ! GBB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017880 name: GNG10_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 precursor gene" [UniProtKB:P50151] synonym: "GNGT10" EXACT [UniProtKB:P50151] xref: EMBL:AF493877 xref: EMBL:AL135787 xref: EMBL:BC010384 xref: EMBL:BC015206 xref: EMBL:BC016319 xref: EMBL:BC072671 xref: EMBL:BC107574 xref: EMBL:U31383 xref: HGNC:HGNC:4402 xref: UniGene:Hs.534196 xref: UniGene:Hs.656890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055444 ! GBG10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017881 name: GNG11_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 precursor gene" [UniProtKB:P61952] synonym: "GNGT11" EXACT [UniProtKB:P61952] xref: EMBL:AC002076 xref: EMBL:AF493878 xref: EMBL:BC009709 xref: EMBL:U31384 xref: HGNC:HGNC:4403 xref: UniGene:Hs.83381 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055614 ! GBG11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017882 name: GNG12_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor gene" [UniProtKB:Q9UBI6] xref: EMBL:AF119663 xref: EMBL:AF188181 xref: EMBL:AF365871 xref: EMBL:AF493879 xref: EMBL:BC005940 xref: HGNC:HGNC:19663 xref: UniGene:Hs.431101 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059075 ! GBG12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017883 name: GNG13_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 precursor gene" [UniProtKB:Q9P2W3] xref: EMBL:AB030207 xref: EMBL:AE006465 xref: EMBL:AF493880 xref: EMBL:AL031033 xref: EMBL:AY029486 xref: EMBL:BC093760 xref: EMBL:BC095525 xref: HGNC:HGNC:14131 xref: UniGene:Hs.247888 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059061 ! GBG13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017884 name: GNGT1_human def: "Guanine nucleotide-binding protein G(T) subunit gamma-T1 precursor gene" [UniProtKB:P63211] xref: EMBL:AC002076 xref: EMBL:AF493869 xref: EMBL:BC029367 xref: EMBL:CR456912 xref: EMBL:S62026 xref: EMBL:S62027 xref: EMBL:U41492 xref: HGNC:HGNC:4411 xref: UniGene:Hs.702084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055631 ! GBG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017885 name: GNG2_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor gene" [UniProtKB:P59768] xref: EMBL:AF493870 xref: EMBL:BC020774 xref: EMBL:BC060856 xref: HGNC:HGNC:4404 xref: UniGene:Hs.187772 xref: UniGene:Hs.701855 xref: UniGene:Hs.705393 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055589 ! GBG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017886 name: GNG3_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 precursor gene" [UniProtKB:P63215] synonym: "GNGT3" EXACT [UniProtKB:P63215] xref: EMBL:AF087900 xref: EMBL:AF092129 xref: EMBL:AF188177 xref: EMBL:AF493871 xref: EMBL:BC015563 xref: HGNC:HGNC:4405 xref: UniGene:Hs.179915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055632 ! GBG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017887 name: GNG4_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor gene" [UniProtKB:P50150] synonym: "GNGT4" EXACT [UniProtKB:P50150] xref: EMBL:AF493872 xref: EMBL:BC022485 xref: EMBL:U31382 xref: HGNC:HGNC:4407 xref: UniGene:Hs.159711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055443 ! GBG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017888 name: GNG5_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 precursor gene" [UniProtKB:P63218] synonym: "GNGT5" EXACT [UniProtKB:P63218] xref: EMBL:AF038955 xref: EMBL:AF085708 xref: EMBL:AF085709 xref: EMBL:AF493873 xref: EMBL:AL359762 xref: EMBL:BC003563 xref: EMBL:BT006823 xref: HGNC:HGNC:4408 xref: UniGene:Hs.645427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055633 ! GBG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017889 name: GNG7_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 precursor gene" [UniProtKB:O60262] synonym: "GNGT7" EXACT [UniProtKB:O60262] xref: EMBL:AB010414 xref: EMBL:AC005512 xref: EMBL:AF493874 xref: EMBL:BC014466 xref: EMBL:BC053630 xref: HGNC:HGNC:4410 xref: UniGene:Hs.515544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054537 ! GBG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017890 name: GNG8_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 precursor gene" [UniProtKB:Q9UK08] synonym: "GNG9" EXACT [UniProtKB:Q9UK08] synonym: "GNGT9" EXACT [UniProtKB:Q9UK08] xref: EMBL:AF188179 xref: EMBL:AF493875 xref: EMBL:BC095514 xref: HGNC:HGNC:19664 xref: UniGene:Hs.283961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059182 ! GBG8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017891 name: GNGT2_human def: "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 precursor gene" [UniProtKB:O14610] synonym: "GNG8" EXACT [UniProtKB:O14610] synonym: "GNG9" EXACT [UniProtKB:O14610] synonym: "GNGT8" EXACT [UniProtKB:O14610] xref: EMBL:AF001159 xref: EMBL:AF001160 xref: EMBL:AF365870 xref: EMBL:AF493876 xref: EMBL:BC008663 xref: HGNC:HGNC:4412 xref: UniGene:Hs.181781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054356 ! GBGT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017892 name: GCFC_human def: "GC-rich sequence DNA-binding factor homolog gene" [UniProtKB:Q9Y5B6] synonym: "C21orf66" EXACT [UniProtKB:Q9Y5B6] xref: EMBL:AF153208 xref: EMBL:AF231920 xref: EMBL:AJ279080 xref: EMBL:AJ279081 xref: EMBL:AY033903 xref: EMBL:AY033904 xref: EMBL:AY033905 xref: EMBL:AY033906 xref: HGNC:HGNC:13579 xref: UniGene:Hs.644004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059376 ! GCFC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017893 name: TCF9_human def: "GC-rich sequence DNA-binding factor gene" [UniProtKB:P16383] synonym: "C2orf3" EXACT [UniProtKB:P16383] xref: EMBL:AC005034 xref: EMBL:BC064559 xref: EMBL:M29204 xref: HGNC:HGNC:1317 xref: UniGene:Hs.303808 xref: UniGene:Hs.44024 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055049 ! GCF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017894 name: GCM1_human def: "Chorion-specific transcription factor GCMa gene" [UniProtKB:Q9NP62] synonym: "GCMA" EXACT [UniProtKB:Q9NP62] xref: EMBL:AB026493 xref: EMBL:AB041714 xref: EMBL:AB041716 xref: EMBL:AB047819 xref: EMBL:AL512347 xref: EMBL:BC096288 xref: EMBL:D88613 xref: HGNC:HGNC:4197 xref: UniGene:Hs.28346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058834 ! GCM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017895 name: GCM2_human def: "Chorion-specific transcription factor GCMb gene" [UniProtKB:O75603] synonym: "GCMB" EXACT [UniProtKB:O75603] xref: EMBL:AF079550 xref: EMBL:AF091149 xref: EMBL:AL024498 xref: EMBL:AL357497 xref: EMBL:BC069603 xref: EMBL:BC117316 xref: EMBL:BC117318 xref: HGNC:HGNC:4198 xref: UniGene:Hs.227098 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054656 ! GCM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017896 name: GCN1L1_human def: "Translational activator GCN1 gene" [UniProtKB:Q92616] synonym: "KIAA0219" EXACT [UniProtKB:Q92616] xref: EMBL:AC004812 xref: EMBL:BC021129 xref: EMBL:BC032335 xref: EMBL:BC046177 xref: EMBL:BC064346 xref: EMBL:D86973 xref: EMBL:U77700 xref: EMBL:U88836 xref: EMBL:U88837 xref: HGNC:HGNC:4199 xref: UniGene:Hs.298716 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058073 ! GCN1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017897 name: NR3C1_human def: "Glucocorticoid receptor gene" [UniProtKB:P04150] synonym: "GRL" EXACT [UniProtKB:P04150] xref: EMBL:AC004782 xref: EMBL:AC005601 xref: EMBL:AC091925 xref: EMBL:AK223594 xref: EMBL:AY436590 xref: EMBL:BC015610 xref: EMBL:BX640610 xref: EMBL:M69104 xref: EMBL:M73816 xref: EMBL:S68378 xref: EMBL:U01351 xref: EMBL:U78506 xref: EMBL:U78507 xref: EMBL:U78508 xref: EMBL:U78509 xref: EMBL:U78510 xref: EMBL:U78511 xref: EMBL:U78512 xref: EMBL:U80946 xref: EMBL:U80947 xref: EMBL:X03225 xref: EMBL:X03348 xref: HGNC:HGNC:7978 xref: UniGene:Hs.122926 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054886 ! GCR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017898 name: GUCY1A2_human def: "Guanylate cyclase soluble subunit alpha-2 gene" [UniProtKB:P33402] synonym: "GUC1A2" EXACT [UniProtKB:P33402] synonym: "GUCSA2" EXACT [UniProtKB:P33402] xref: EMBL:X63282 xref: EMBL:Z50053 xref: HGNC:HGNC:4684 xref: UniGene:Hs.654555 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055267 ! GCYA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017899 name: GUCY1A3_human def: "Guanylate cyclase soluble subunit alpha-3 gene" [UniProtKB:Q02108] synonym: "GUC1A3" EXACT [UniProtKB:Q02108] synonym: "GUCSA3" EXACT [UniProtKB:Q02108] synonym: "GUCY1A1" EXACT [UniProtKB:Q02108] xref: EMBL:BC028384 xref: EMBL:U58855 xref: EMBL:X66534 xref: EMBL:Y15723 xref: HGNC:HGNC:4685 xref: UniGene:Hs.24258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055705 ! GCYA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017900 name: GUCY1B3_human def: "Guanylate cyclase soluble subunit beta-1 gene" [UniProtKB:Q02153] synonym: "GUC1B3" EXACT [UniProtKB:Q02153] synonym: "GUCSB3" EXACT [UniProtKB:Q02153] synonym: "GUCY1B1" EXACT [UniProtKB:Q02153] xref: EMBL:AF020340 xref: EMBL:BC047620 xref: EMBL:X66533 xref: HGNC:HGNC:4687 xref: UniGene:Hs.77890 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055706 ! GCYB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017901 name: GUCY1B2_human def: "Guanylate cyclase soluble subunit beta-2 gene" [UniProtKB:O75343] xref: EMBL:AF038499 xref: EMBL:AF218383 xref: HGNC:HGNC:4686 xref: UniGene:Hs.411573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054619 ! GCYB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017902 name: AGL_human def: "Glycogen debranching enzyme gene" [UniProtKB:P35573] synonym: "GDE" EXACT [UniProtKB:P35573] xref: EMBL:AB035443 xref: EMBL:BC078663 xref: EMBL:M85168 xref: EMBL:U84007 xref: EMBL:U84008 xref: EMBL:U84009 xref: EMBL:U84010 xref: EMBL:U84011 xref: HGNC:HGNC:321 xref: UniGene:Hs.904 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026523 ! GDE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017903 name: GDF11_human def: "Growth/differentiation factor 11 precursor gene" [UniProtKB:O95390] synonym: "BMP11" EXACT [UniProtKB:O95390] xref: EMBL:AF028333 xref: EMBL:AF028334 xref: EMBL:AF100907 xref: HGNC:HGNC:4216 xref: UniGene:Hs.643604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054756 ! GDF11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017904 name: GDF15_human def: "Growth/differentiation factor 15 precursor gene" [UniProtKB:Q99988] synonym: "MIC1" EXACT [UniProtKB:Q99988] synonym: "PDF" EXACT [UniProtKB:Q99988] synonym: "PLAB" EXACT [UniProtKB:Q99988] synonym: "PTGFB" EXACT [UniProtKB:Q99988] xref: EMBL:AB000584 xref: EMBL:AF003934 xref: EMBL:AF008303 xref: EMBL:AF019770 xref: EMBL:AF173860 xref: EMBL:AK291530 xref: EMBL:BC000529 xref: EMBL:BC008962 xref: EMBL:BT019465 xref: EMBL:CH471106 xref: EMBL:U88323 xref: HGNC:HGNC:30142 xref: UniGene:Hs.616962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058466 ! GDF15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017905 name: GDF2_human def: "Growth/differentiation factor 2 precursor gene" [UniProtKB:Q9UK05] synonym: "BMP9" EXACT [UniProtKB:Q9UK05] xref: EMBL:AF156891 xref: EMBL:AF188285 xref: EMBL:BC069643 xref: EMBL:BC074921 xref: HGNC:HGNC:4217 xref: UniGene:Hs.279463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059181 ! GDF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017906 name: GDF6_human def: "Growth/differentiation factor 6 precursor gene" [UniProtKB:Q6KF10] synonym: "GDF16" EXACT [UniProtKB:Q6KF10] xref: EMBL:AJ537424 xref: EMBL:BC043222 xref: HGNC:HGNC:4221 xref: UniGene:Hs.492277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056834 ! GDF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017907 name: MSTN_human def: "Growth/differentiation factor 8 precursor gene" [UniProtKB:O14793] synonym: "GDF8" EXACT [UniProtKB:O14793] xref: EMBL:AF019627 xref: EMBL:AF104922 xref: EMBL:BC074757 xref: HGNC:HGNC:4223 xref: UniGene:Hs.41565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054376 ! GDF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017908 name: GDI1_human def: "Rab GDP dissociation inhibitor alpha gene" [UniProtKB:P31150] synonym: "GDIL" EXACT [UniProtKB:P31150] synonym: "OPHN2" EXACT [UniProtKB:P31150] synonym: "RABGDIA" EXACT [UniProtKB:P31150] synonym: "XAP4" EXACT [UniProtKB:P31150] xref: EMBL:AB101741 xref: EMBL:AB101742 xref: EMBL:AB101743 xref: EMBL:AB101744 xref: EMBL:AB101745 xref: EMBL:AB101746 xref: EMBL:AB101747 xref: EMBL:AB101748 xref: EMBL:AB101749 xref: EMBL:AB101750 xref: EMBL:AB101751 xref: EMBL:AB101752 xref: EMBL:AB101753 xref: EMBL:AB101754 xref: EMBL:AB101755 xref: EMBL:AB101756 xref: EMBL:AB101757 xref: EMBL:AB101758 xref: EMBL:AB101759 xref: EMBL:AB101760 xref: EMBL:AB101771 xref: EMBL:AB101772 xref: EMBL:AB101773 xref: EMBL:AB101774 xref: EMBL:AB101775 xref: EMBL:AB101776 xref: EMBL:AB101777 xref: EMBL:AB101778 xref: EMBL:AB101779 xref: EMBL:AB101780 xref: EMBL:AB101781 xref: EMBL:AB101782 xref: EMBL:AB101783 xref: EMBL:AB101784 xref: EMBL:AB101785 xref: EMBL:AB101786 xref: EMBL:AB101787 xref: EMBL:AB101788 xref: EMBL:AB101789 xref: EMBL:AB101790 xref: EMBL:AB101801 xref: EMBL:AB101802 xref: EMBL:AB101803 xref: EMBL:AB101804 xref: EMBL:AB101805 xref: EMBL:AB101806 xref: EMBL:AB101807 xref: EMBL:AB101808 xref: EMBL:AB101809 xref: EMBL:AB101810 xref: EMBL:AB101811 xref: EMBL:AB101812 xref: EMBL:AB101813 xref: EMBL:AB101814 xref: EMBL:AB101815 xref: EMBL:AB101816 xref: EMBL:AB101817 xref: EMBL:AB101818 xref: EMBL:AB101819 xref: EMBL:AB101820 xref: EMBL:AB101831 xref: EMBL:AB101832 xref: EMBL:AB101833 xref: EMBL:AB101834 xref: EMBL:AB101835 xref: EMBL:AB101836 xref: EMBL:AB101837 xref: EMBL:AB101838 xref: EMBL:AB101839 xref: EMBL:AB101840 xref: EMBL:AB101841 xref: EMBL:AB101842 xref: EMBL:AB101843 xref: EMBL:AB101844 xref: EMBL:AB101845 xref: EMBL:AB101846 xref: EMBL:AB101847 xref: EMBL:AB101848 xref: EMBL:AB101849 xref: EMBL:AB101850 xref: EMBL:AF400433 xref: EMBL:BC000317 xref: EMBL:BC012201 xref: EMBL:D45021 xref: EMBL:L05086 xref: EMBL:L44140 xref: EMBL:U14623 xref: EMBL:X79353 xref: EMBL:X79354 xref: EMBL:X79355 xref: EMBL:X79356 xref: EMBL:X79357 xref: EMBL:X79358 xref: EMBL:X79359 xref: EMBL:X79360 xref: EMBL:X79361 xref: EMBL:X79362 xref: EMBL:X79363 xref: EMBL:X79364 xref: HGNC:HGNC:4226 xref: UniGene:Hs.74576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055233 ! GDIA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017909 name: GDI2_human def: "Rab GDP dissociation inhibitor beta gene" [UniProtKB:P50395] synonym: "RABGDIB" EXACT [UniProtKB:P50395] xref: EMBL:AF144713 xref: EMBL:BC005145 xref: EMBL:BT006868 xref: EMBL:D13988 xref: EMBL:Y13286 xref: EMBL:Y13287 xref: EMBL:Y13288 xref: EMBL:Y13289 xref: EMBL:Y13290 xref: EMBL:Y13291 xref: EMBL:Y13292 xref: EMBL:Y13293 xref: EMBL:Y13294 xref: EMBL:Y13295 xref: EMBL:Y13296 xref: EMBL:Y13297 xref: HGNC:HGNC:4227 xref: UniGene:Hs.299055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055448 ! GDIB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017910 name: ARHGDIB_human def: "Rho GDP-dissociation inhibitor 2 gene" [UniProtKB:P52566] synonym: "GDIA2" EXACT [UniProtKB:P52566] synonym: "GDID4" EXACT [UniProtKB:P52566] synonym: "RAP1GN1" EXACT [UniProtKB:P52566] xref: EMBL:AF498927 xref: EMBL:BC009200 xref: EMBL:L07916 xref: EMBL:L20688 xref: EMBL:X69549 xref: HGNC:HGNC:679 xref: UniGene:Hs.504877 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055486 ! GDIR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017911 name: ARHGDIG_human def: "Rho GDP-dissociation inhibitor 3 gene" [UniProtKB:Q99819] xref: EMBL:AB127078 xref: EMBL:AE006463 xref: EMBL:AF080237 xref: EMBL:AF498928 xref: EMBL:BC047699 xref: EMBL:U82532 xref: EMBL:Z69667 xref: HGNC:HGNC:680 xref: UniGene:Hs.647388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058457 ! GDIR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017912 name: GDNF_human def: "Glial cell line-derived neurotrophic factor precursor gene" [UniProtKB:P39905] xref: EMBL:AF053748 xref: EMBL:AF063586 xref: EMBL:AJ001896 xref: EMBL:AJ001897 xref: EMBL:AJ001898 xref: EMBL:AJ001899 xref: EMBL:AJ001900 xref: EMBL:AY052832 xref: EMBL:BC069119 xref: EMBL:BC069369 xref: EMBL:BC128108 xref: EMBL:BC128109 xref: EMBL:CR541923 xref: EMBL:L19062 xref: EMBL:L19063 xref: HGNC:HGNC:4232 xref: UniGene:Hs.248114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055323 ! GDNF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017913 name: SERPINE2_human def: "Glia-derived nexin precursor gene" [UniProtKB:P07093] synonym: "PI7" EXACT [UniProtKB:P07093] synonym: "PN1" EXACT [UniProtKB:P07093] xref: EMBL:BC015663 xref: EMBL:M17783 xref: HGNC:HGNC:8951 xref: UniGene:Hs.38449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054908 ! GDN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017914 name: GEFT_human def: "Guanine nucleotide exchange factor GEFT gene" [UniProtKB:Q86VW2] xref: EMBL:AB370196 xref: EMBL:AC025165 xref: EMBL:AF487514 xref: EMBL:BC012860 xref: EMBL:BC018536 xref: EMBL:BC047559 xref: EMBL:CH471054 xref: UniGene:Hs.61581 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054150 ! A9CQZ6_HUMAN relationship: codes_for CCO:B0057267 ! GEFT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017915 name: GEM_human def: "GTP-binding protein GEM gene" [UniProtKB:P55040] synonym: "KIR" EXACT [UniProtKB:P55040] xref: EMBL:BC022010 xref: EMBL:U10550 xref: EMBL:U13052 xref: HGNC:HGNC:4234 xref: UniGene:Hs.654463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055523 ! GEM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017916 name: GFRA1_human def: "GDNF family receptor alpha-1 precursor gene" [UniProtKB:P56159] synonym: "GDNFRA" EXACT [UniProtKB:P56159] synonym: "RETL1" EXACT [UniProtKB:P56159] synonym: "TRNR1" EXACT [UniProtKB:P56159] xref: EMBL:AF038411 xref: EMBL:AF038412 xref: EMBL:AF038413 xref: EMBL:AF038414 xref: EMBL:AF038415 xref: EMBL:AF038416 xref: EMBL:AF038417 xref: EMBL:AF038418 xref: EMBL:AF038419 xref: EMBL:AF038420 xref: EMBL:AF038421 xref: EMBL:AF042080 xref: EMBL:AF058990 xref: EMBL:AF058991 xref: EMBL:AF058992 xref: EMBL:AF058993 xref: EMBL:AF058994 xref: EMBL:AF058995 xref: EMBL:AF058996 xref: EMBL:AF058997 xref: EMBL:AF058998 xref: EMBL:AF058999 xref: EMBL:BC014962 xref: EMBL:U95847 xref: EMBL:U97144 xref: HGNC:HGNC:4243 xref: UniGene:Hs.591913 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055538 ! GFRA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017917 name: GFRA2_human def: "GDNF family receptor alpha-2 precursor gene" [UniProtKB:O00451] synonym: "GDNFRB" EXACT [UniProtKB:O00451] synonym: "RETL2" EXACT [UniProtKB:O00451] synonym: "TRNR2" EXACT [UniProtKB:O00451] xref: EMBL:AF002700 xref: EMBL:AY326396 xref: EMBL:BC041688 xref: EMBL:U93703 xref: EMBL:U97145 xref: HGNC:HGNC:4244 xref: UniGene:Hs.441202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054321 ! GFRA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017918 name: GFRA3_human def: "GDNF family receptor alpha-3 precursor gene" [UniProtKB:O60609] synonym: "UNQ339/PRO538/PRO3664" EXACT [UniProtKB:O60609] xref: EMBL:AF051767 xref: EMBL:AY358997 xref: EMBL:AY359037 xref: EMBL:BC037951 xref: HGNC:HGNC:4245 xref: UniGene:Hs.58042 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054570 ! GFRA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017919 name: GFRAL_human def: "GDNF family receptor alpha-like precursor gene" [UniProtKB:Q6UXV0] synonym: "C6orf144" EXACT [UniProtKB:Q6UXV0] synonym: "UNQ9356/PRO34128" EXACT [UniProtKB:Q6UXV0] xref: EMBL:AL592426 xref: EMBL:AY358198 xref: HGNC:HGNC:32789 xref: UniGene:Hs.526967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056955 ! GFRAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017920 name: GHRHR_human def: "Growth hormone-releasing hormone receptor precursor gene" [UniProtKB:Q02643] xref: EMBL:AB065701 xref: EMBL:AC005155 xref: EMBL:AF282262 xref: EMBL:AY557192 xref: EMBL:CH471073 xref: EMBL:L01406 xref: EMBL:L09237 xref: EMBL:U42222 xref: EMBL:U42223 xref: EMBL:U42224 xref: EMBL:U42225 xref: HGNC:HGNC:4266 xref: UniGene:Hs.767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055713 ! GHRHR_HUMAN relationship: codes_for CCO:B0058775 ! Q9HB42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017921 name: GHSR_human def: "Growth hormone secretagogue receptor type 1 gene" [UniProtKB:Q92847] xref: EMBL:AF369786 xref: EMBL:AY322544 xref: EMBL:AY429112 xref: EMBL:BC113547 xref: EMBL:U60179 xref: EMBL:U60181 xref: HGNC:HGNC:4267 xref: UniGene:Hs.248115 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058105 ! GHSR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017922 name: GIPC1_human def: "PDZ domain-containing protein GIPC1 gene" [UniProtKB:O14908] synonym: "C19orf3" EXACT [UniProtKB:O14908] synonym: "GIPC" EXACT [UniProtKB:O14908] synonym: "RGS19IP1" EXACT [UniProtKB:O14908] xref: EMBL:AF028824 xref: EMBL:AF089816 xref: EMBL:BC000410 xref: EMBL:BC004226 xref: EMBL:BC012810 xref: EMBL:BC016169 xref: HGNC:HGNC:1226 xref: UniGene:Hs.655012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054391 ! GIPC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017923 name: GIPR_human def: "Gastric inhibitory polypeptide receptor precursor gene" [UniProtKB:P48546] xref: EMBL:AC006132 xref: EMBL:AC007191 xref: EMBL:BC093723 xref: EMBL:BC101673 xref: EMBL:D49559 xref: EMBL:S79852 xref: EMBL:U39231 xref: EMBL:X81832 xref: HGNC:HGNC:4271 xref: UniGene:Hs.658534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015124 ! GIPR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017924 name: GIP_human def: "Gastric inhibitory polypeptide precursor gene" [UniProtKB:P09681] xref: EMBL:BC069100 xref: EMBL:BC069663 xref: EMBL:BC069686 xref: EMBL:BC069746 xref: EMBL:BC096146 xref: EMBL:BC096147 xref: EMBL:BC096148 xref: EMBL:BC096149 xref: EMBL:M18185 xref: EMBL:M31675 xref: EMBL:M31676 xref: EMBL:M31677 xref: EMBL:M31678 xref: EMBL:M31679 xref: HGNC:HGNC:4270 xref: UniGene:Hs.1454 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054948 ! GIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017925 name: GIT2_human def: "ARF GTPase-activating protein GIT2 gene" [UniProtKB:Q14161] synonym: "KIAA0148" EXACT [UniProtKB:Q14161] xref: EMBL:AF124491 xref: EMBL:BC001379 xref: EMBL:BC014223 xref: EMBL:BT007312 xref: EMBL:D63482 xref: HGNC:HGNC:4273 xref: UniGene:Hs.434996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055967 ! GIT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017926 name: GKAP1_human def: "G kinase-anchoring protein 1 gene" [UniProtKB:Q5VSY0] synonym: "FKSG21" EXACT [UniProtKB:Q5VSY0] synonym: "GKAP42" EXACT [UniProtKB:Q5VSY0] xref: EMBL:AB033131 xref: EMBL:AB033132 xref: EMBL:AF319476 xref: EMBL:AK058198 xref: EMBL:AL354733 xref: EMBL:AL662787 xref: EMBL:BC014476 xref: EMBL:CH471089 xref: HGNC:HGNC:17496 xref: UniGene:Hs.522255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056643 ! GKAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017927 name: GLI1_human def: "Zinc finger protein GLI1 gene" [UniProtKB:P08151] synonym: "GLI" EXACT [UniProtKB:P08151] xref: EMBL:AF316573 xref: EMBL:BC013000 xref: EMBL:X07384 xref: HGNC:HGNC:4317 xref: UniGene:Hs.632702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054922 ! GLI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017928 name: GLI2_human def: "Zinc finger protein GLI2 gene" [UniProtKB:P10070] synonym: "THP" EXACT [UniProtKB:P10070] xref: EMBL:AB007295 xref: EMBL:AB007296 xref: EMBL:AB007297 xref: EMBL:AB007298 xref: EMBL:AC016764 xref: EMBL:AC017033 xref: EMBL:D14827 xref: EMBL:D14828 xref: EMBL:DQ086814 xref: EMBL:M20672 xref: EMBL:M20673 xref: HGNC:HGNC:4318 xref: UniGene:Hs.111867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054965 ! GLI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017929 name: GLMN_human def: "Glomulin gene" [UniProtKB:Q92990] synonym: "FAP48" EXACT [UniProtKB:Q92990] synonym: "FAP68" EXACT [UniProtKB:Q92990] synonym: "VMGLOM" EXACT [UniProtKB:Q92990] xref: EMBL:AJ302727 xref: EMBL:AJ302728 xref: EMBL:AJ302729 xref: EMBL:AJ302730 xref: EMBL:AJ302731 xref: EMBL:AJ302732 xref: EMBL:AJ302733 xref: EMBL:AJ302734 xref: EMBL:AJ302735 xref: EMBL:AJ347709 xref: EMBL:BC001257 xref: EMBL:U73704 xref: HGNC:HGNC:14373 xref: UniGene:Hs.49105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058117 ! GLMN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017930 name: GLP1R_human def: "Glucagon-like peptide 1 receptor precursor gene" [UniProtKB:P43220] xref: EMBL:AB065685 xref: EMBL:AL035690 xref: EMBL:AY439112 xref: EMBL:BC112126 xref: EMBL:BC113493 xref: EMBL:L23503 xref: EMBL:U01104 xref: EMBL:U01156 xref: EMBL:U01157 xref: EMBL:U10037 xref: EMBL:U66062 xref: HGNC:HGNC:4324 xref: UniGene:Hs.389103 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015123 ! GLP1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017931 name: GLP1_human def: "GATA-like protein 1 gene" [UniProtKB:P0C6A0] xref: EMBL:AC011511 xref: EMBL:AK096830 xref: EMBL:BC044225 xref: UniGene:Hs.654865 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054962 ! GLP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017932 name: GLP2R_human def: "Glucagon-like peptide 2 receptor precursor gene" [UniProtKB:O95838] xref: EMBL:AF105367 xref: EMBL:BC096262 xref: HGNC:HGNC:4325 xref: UniGene:Hs.248202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015134 ! GLP2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017933 name: GLRX2_human def: "Glutaredoxin-2, mitochondrial precursor gene" [UniProtKB:Q9NS18] synonym: "CGI-133" EXACT [UniProtKB:Q9NS18] synonym: "GRX2" EXACT [UniProtKB:Q9NS18] xref: EMBL:AF132495 xref: EMBL:AF151891 xref: EMBL:AF290514 xref: EMBL:AL136370 xref: EMBL:AY038988 xref: EMBL:BC028113 xref: EMBL:DQ194815 xref: HGNC:HGNC:16065 xref: UniGene:Hs.458283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058907 ! GLRX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017934 name: GCGR_human def: "Glucagon receptor precursor gene" [UniProtKB:P47871] xref: EMBL:BC104854 xref: EMBL:BC112041 xref: EMBL:L20316 xref: EMBL:L24751 xref: EMBL:U03469 xref: HGNC:HGNC:4192 xref: UniGene:Hs.208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015122 ! GLR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017935 name: GCG_human def: "Glucagon precursor gene" [UniProtKB:P01275] xref: EMBL:AC007750 xref: EMBL:BC005278 xref: EMBL:BT006813 xref: EMBL:J04040 xref: EMBL:V01515 xref: EMBL:X03991 xref: HGNC:HGNC:4191 xref: UniGene:Hs.516494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054848 ! GLUC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017936 name: GMCL1_human def: "Germ cell-less protein-like 1 gene" [UniProtKB:Q96IK5] synonym: "GCL" EXACT [UniProtKB:Q96IK5] xref: EMBL:AK023119 xref: EMBL:AK023261 xref: EMBL:AK024042 xref: EMBL:BC007420 xref: HGNC:HGNC:23843 xref: UniGene:Hs.293971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058230 ! GMCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017937 name: GMCL1L_human def: "Germ cell-less protein-like 1-like gene" [UniProtKB:Q8NEA9] synonym: "GCL" EXACT [UniProtKB:Q8NEA9] xref: EMBL:BC024184 xref: EMBL:BC024185 xref: EMBL:BC033886 xref: HGNC:HGNC:19717 xref: UniGene:Hs.591738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057588 ! GMCLL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017938 name: GMEB1_human def: "Glucocorticoid modulatory element-binding protein 1 gene" [UniProtKB:Q9Y692] xref: EMBL:AF099013 xref: EMBL:AF173868 xref: EMBL:AF203694 xref: EMBL:AK000892 xref: EMBL:BC001473 xref: HGNC:HGNC:4370 xref: UniGene:Hs.632373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059401 ! GMEB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017939 name: GMEB2_human def: "Glucocorticoid modulatory element-binding protein 2 gene" [UniProtKB:Q9UKD1] synonym: "KIAA1269" EXACT [UniProtKB:Q9UKD1] xref: EMBL:AB033095 xref: EMBL:AF173867 xref: EMBL:AL121907 xref: EMBL:AL133646 xref: EMBL:AL353715 xref: EMBL:BC036305 xref: HGNC:HGNC:4371 xref: UniGene:Hs.473286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059191 ! GMEB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017940 name: GMIP_human def: "GEM-interacting protein gene" [UniProtKB:Q9P107] xref: EMBL:AF132541 xref: EMBL:BC126436 xref: EMBL:CH471106 xref: HGNC:HGNC:24852 xref: UniGene:Hs.49427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059036 ! GMIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017941 name: GNA12_human def: "Guanine nucleotide-binding protein subunit alpha-12 gene" [UniProtKB:Q03113] xref: EMBL:AC004933 xref: EMBL:AC006028 xref: EMBL:AF493901 xref: EMBL:BC111464 xref: EMBL:L01694 xref: HGNC:HGNC:4380 xref: UniGene:Hs.487341 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055721 ! GNA12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017942 name: GNA15_human def: "Guanine nucleotide-binding protein subunit alpha-15 gene" [UniProtKB:P30679] synonym: "GNA16" EXACT [UniProtKB:P30679] xref: EMBL:AC005262 xref: EMBL:AC005264 xref: EMBL:AF493904 xref: EMBL:BC013585 xref: EMBL:M63904 xref: HGNC:HGNC:4383 xref: UniGene:Hs.73797 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055225 ! GNA15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017943 name: GNAL_human def: "Guanine nucleotide-binding protein G(olf) subunit alpha gene" [UniProtKB:P38405] xref: EMBL:AF493893 xref: EMBL:BC050021 xref: EMBL:CH471113 xref: EMBL:L10665 xref: EMBL:U55180 xref: EMBL:U55181 xref: EMBL:U55182 xref: EMBL:U55183 xref: EMBL:U55184 xref: HGNC:HGNC:4388 xref: UniGene:Hs.136295 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027551 ! GNAL_HUMAN relationship: codes_for CCO:B0027562 ! Q86XU3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017944 name: GNAS_human def: "Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas gene" [UniProtKB:Q5JWF2] synonym: "GNAS1" EXACT [UniProtKB:Q5JWF2] xref: EMBL:AF105253 xref: EMBL:AF107846 xref: EMBL:AF493897 xref: EMBL:AF493898 xref: EMBL:AJ009849 xref: EMBL:AJ224867 xref: EMBL:AJ224868 xref: EMBL:AJ251760 xref: EMBL:AL109840 xref: EMBL:AL121917 xref: EMBL:AL132655 xref: EMBL:AY898804 xref: EMBL:BC002722 xref: EMBL:BC008855 xref: EMBL:BC022875 xref: EMBL:BC066923 xref: EMBL:BC089157 xref: EMBL:BC104928 xref: EMBL:BT009905 xref: EMBL:M14631 xref: EMBL:M21139 xref: EMBL:M21140 xref: EMBL:M21141 xref: EMBL:M21142 xref: EMBL:M21740 xref: EMBL:M21741 xref: EMBL:U12466 xref: EMBL:X04408 xref: EMBL:X04409 xref: EMBL:X07036 xref: HGNC:HGNC:4392 xref: UniGene:Hs.125898 xref: UniGene:Hs.694849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027548 ! Q5JWE9_HUMAN relationship: codes_for CCO:B0027550 ! GNAS2_HUMAN relationship: codes_for CCO:B0027553 ! Q5FWY2_HUMAN relationship: codes_for CCO:B0027554 ! GNAS1_HUMAN relationship: codes_for CCO:B0027556 ! A6NI00_HUMAN relationship: codes_for CCO:B0027557 ! Q5JW64_HUMAN relationship: codes_for CCO:B0027559 ! Q5JWD1_HUMAN relationship: codes_for CCO:B0027564 ! Q5JWE8_HUMAN relationship: codes_for CCO:B0054765 ! GNAS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017945 name: GNB1L_human def: "Guanine nucleotide-binding protein subunit beta-like protein 1 gene" [UniProtKB:Q9BYB4] synonym: "FKSG1" EXACT [UniProtKB:Q9BYB4] synonym: "GY2" EXACT [UniProtKB:Q9BYB4] synonym: "KIAA1645" EXACT [UniProtKB:Q9BYB4] synonym: "WDR14" EXACT [UniProtKB:Q9BYB4] xref: EMBL:AB049212 xref: EMBL:AB051432 xref: EMBL:AF238328 xref: EMBL:AF301895 xref: EMBL:AY007378 xref: EMBL:BC012060 xref: EMBL:CR456496 xref: HGNC:HGNC:4397 xref: UniGene:Hs.105642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058574 ! GNB1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017946 name: GNL1_human def: "Guanine nucleotide-binding protein-like 1 gene" [UniProtKB:P36915] synonym: "HSR1" EXACT [UniProtKB:P36915] xref: EMBL:AL662800 xref: EMBL:AL662825 xref: EMBL:BC013959 xref: EMBL:BC018366 xref: EMBL:BT006648 xref: EMBL:BX000357 xref: EMBL:BX248518 xref: EMBL:L25665 xref: HGNC:HGNC:4413 xref: UniGene:Hs.83147 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055312 ! GNL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017947 name: GNRHR_human def: "Gonadotropin-releasing hormone receptor gene" [UniProtKB:P30968] synonym: "GRHR" EXACT [UniProtKB:P30968] xref: EMBL:AF001950 xref: EMBL:AF001951 xref: EMBL:AF001952 xref: EMBL:AY392011 xref: EMBL:BC113546 xref: EMBL:L03380 xref: EMBL:L07949 xref: EMBL:S60587 xref: EMBL:S77472 xref: EMBL:Z81148 xref: EMBL:Z99995 xref: HGNC:HGNC:4421 xref: UniGene:Hs.407587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055229 ! GNRHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017948 name: GNRHR2_human def: "Putative gonadotropin-releasing hormone II receptor gene" [UniProtKB:Q96P88] xref: EMBL:AB239331 xref: EMBL:AF403014 xref: EMBL:AL160282 xref: EMBL:AY081843 xref: EMBL:DQ266410 xref: HGNC:HGNC:16341 xref: UniGene:Hs.356873 xref: UniGene:Hs.654719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053797 ! A6NDW2_HUMAN relationship: codes_for CCO:B0056216 ! Q2MZ38_HUMAN relationship: codes_for CCO:B0058326 ! GNRR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017949 name: GNRH1_human def: "Progonadoliberin-1 precursor gene" [UniProtKB:P01148] synonym: "GNRH" EXACT [UniProtKB:P01148] synonym: "GRH" EXACT [UniProtKB:P01148] synonym: "LHRH" EXACT [UniProtKB:P01148] xref: EMBL:BC126437 xref: EMBL:BC126463 xref: EMBL:M12578 xref: EMBL:X01059 xref: EMBL:X15215 xref: HGNC:HGNC:4419 xref: UniGene:Hs.701947 xref: UniGene:Hs.82963 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054835 ! GON1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017950 name: GNRH2_human def: "Progonadoliberin-2 precursor gene" [UniProtKB:O43555] xref: EMBL:AF036329 xref: EMBL:AF036330 xref: EMBL:AL121905 xref: EMBL:BC069362 xref: EMBL:BC115400 xref: HGNC:HGNC:4420 xref: UniGene:Hs.129715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054489 ! GON2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017951 name: GON4L_human def: "GON-4-like protein gene" [UniProtKB:Q3T8J9] synonym: "GON4" EXACT [UniProtKB:Q3T8J9] synonym: "KIAA1606" EXACT [UniProtKB:Q3T8J9] xref: EMBL:AB046826 xref: EMBL:AL136565 xref: EMBL:AL139128 xref: EMBL:AL162734 xref: EMBL:AY335490 xref: EMBL:AY335491 xref: EMBL:AY335492 xref: EMBL:BC036740 xref: EMBL:BC064933 xref: EMBL:BX537764 xref: EMBL:BX648043 xref: HGNC:HGNC:25973 xref: UniGene:Hs.656361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056276 ! GON4L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017952 name: GOLT1B_human def: "Vesicle transport protein GOT1B gene" [UniProtKB:Q9Y3E0] synonym: "CGI-141" EXACT [UniProtKB:Q9Y3E0] synonym: "GOT1A" EXACT [UniProtKB:Q9Y3E0] synonym: "HDCMA39P" EXACT [UniProtKB:Q9Y3E0] synonym: "UNQ432/PRO793" EXACT [UniProtKB:Q9Y3E0] xref: EMBL:AB097020 xref: EMBL:AF068292 xref: EMBL:AF151899 xref: EMBL:AL136571 xref: EMBL:AY358975 xref: EMBL:BC012455 xref: EMBL:CR457389 xref: HGNC:HGNC:20175 xref: UniGene:Hs.62275 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059335 ! GOT1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017953 name: GPR101_human def: "Probable G-protein coupled receptor 101 gene" [UniProtKB:Q96P66] xref: EMBL:AB065937 xref: EMBL:AB083588 xref: EMBL:AF411115 xref: EMBL:AL390879 xref: EMBL:BC069439 xref: EMBL:CH471150 xref: HGNC:HGNC:14963 xref: UniGene:Hs.350569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056479 ! Q5JSM8_HUMAN relationship: codes_for CCO:B0058321 ! GP101_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017954 name: GPR110_human def: "Probable G-protein coupled receptor 110 precursor gene" [UniProtKB:Q5T601] synonym: "PGR19" EXACT [UniProtKB:Q5T601] xref: EMBL:AB045123 xref: EMBL:AB065679 xref: EMBL:AK055208 xref: EMBL:AL355518 xref: EMBL:AY140952 xref: EMBL:AY255595 xref: HGNC:HGNC:18990 xref: UniGene:Hs.256897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053827 ! A6NG39_HUMAN relationship: codes_for CCO:B0056586 ! GP110_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017955 name: GPR111_human def: "Probable G-protein coupled receptor 111 gene" [UniProtKB:Q8IZF7] synonym: "PGR20" EXACT [UniProtKB:Q8IZF7] xref: EMBL:AB065684 xref: EMBL:AB083617 xref: EMBL:AL356421 xref: EMBL:AY140953 xref: EMBL:AY255612 xref: EMBL:DQ315369 xref: HGNC:HGNC:18991 xref: UniGene:Hs.150131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056221 ! Q2PNZ1_HUMAN relationship: codes_for CCO:B0057406 ! GP111_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017956 name: GPR113_human def: "Probable G-protein coupled receptor 113 precursor gene" [UniProtKB:Q8IZF5] synonym: "PGR23" EXACT [UniProtKB:Q8IZF5] synonym: "UNQ9196/PRO34000" EXACT [UniProtKB:Q8IZF5] xref: EMBL:AB065959 xref: EMBL:AB083619 xref: EMBL:AY140955 xref: EMBL:AY255611 xref: EMBL:AY358172 xref: EMBL:AY358214 xref: HGNC:HGNC:18989 xref: UniGene:Hs.631878 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057405 ! GP113_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017957 name: GPR114_human def: "Probable G-protein coupled receptor 114 precursor gene" [UniProtKB:Q8IZF4] synonym: "PGR27" EXACT [UniProtKB:Q8IZF4] synonym: "UNQ2524/PRO6017" EXACT [UniProtKB:Q8IZF4] xref: EMBL:AC004382 xref: EMBL:AK160368 xref: EMBL:AK172765 xref: EMBL:AY140956 xref: EMBL:AY255609 xref: EMBL:AY358447 xref: EMBL:BC032401 xref: HGNC:HGNC:19010 xref: UniGene:Hs.187884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054001 ! A8MQV3_HUMAN relationship: codes_for CCO:B0057404 ! GP114_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017958 name: GPR115_human def: "Probable G-protein coupled receptor 115 precursor gene" [UniProtKB:Q8IZF3] synonym: "PGR18" EXACT [UniProtKB:Q8IZF3] xref: EMBL:AB065474 xref: EMBL:AL356421 xref: EMBL:AY140957 xref: EMBL:AY255556 xref: EMBL:DQ315370 xref: HGNC:HGNC:19011 xref: UniGene:Hs.150131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057403 ! GP115_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017959 name: GPR116_human def: "Probable G-protein coupled receptor 116 precursor gene" [UniProtKB:Q8IZF2] synonym: "KIAA0758" EXACT [UniProtKB:Q8IZF2] xref: EMBL:AB018301 xref: EMBL:AL050295 xref: EMBL:AY140958 xref: EMBL:AY255552 xref: EMBL:AY498875 xref: EMBL:BC050087 xref: EMBL:BC066121 xref: HGNC:HGNC:19030 xref: UniGene:Hs.362806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056311 ! Q4G0K7_HUMAN relationship: codes_for CCO:B0057402 ! GP116_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017960 name: GPR119_human def: "Glucose-dependent insulinotropic receptor gene" [UniProtKB:Q8TDV5] xref: EMBL:AB065936 xref: EMBL:AB083584 xref: EMBL:AL035423 xref: EMBL:AY288416 xref: EMBL:BC095502 xref: EMBL:BC101166 xref: EMBL:BC101167 xref: EMBL:BC101168 xref: EMBL:BC126179 xref: EMBL:BC126181 xref: HGNC:HGNC:19060 xref: UniGene:Hs.496762 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057944 ! GP119_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017961 name: GPR120_human def: "G-protein coupled receptor 120 gene" [UniProtKB:Q5NUL3] synonym: "GPR129" EXACT [UniProtKB:Q5NUL3] synonym: "PGR4" EXACT [UniProtKB:Q5NUL3] xref: EMBL:AB115768 xref: EMBL:AL356214 xref: EMBL:AY255573 xref: EMBL:AY288417 xref: HGNC:HGNC:19061 xref: UniGene:Hs.677835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056524 ! GP120_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017962 name: GPR123_human def: "Probable G-protein coupled receptor 123 gene" [UniProtKB:Q86SQ6] synonym: "KIAA1828" EXACT [UniProtKB:Q86SQ6] xref: EMBL:AB058731 xref: EMBL:AL445199 xref: EMBL:AY181241 xref: EMBL:AY255564 xref: HGNC:HGNC:13838 xref: UniGene:Hs.435183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057233 ! GP123_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017963 name: GPR124_human def: "Probable G-protein coupled receptor 124 precursor gene" [UniProtKB:Q96PE1] synonym: "KIAA1531" EXACT [UniProtKB:Q96PE1] synonym: "TEM5" EXACT [UniProtKB:Q96PE1] xref: EMBL:AB040964 xref: EMBL:AF378755 xref: EMBL:AK027296 xref: EMBL:AK074099 xref: EMBL:AL110244 xref: EMBL:AL832524 xref: EMBL:AY181242 xref: HGNC:HGNC:17849 xref: UniGene:Hs.274136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058329 ! GP124_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017964 name: GPR125_human def: "Probable G-protein coupled receptor 125 precursor gene" [UniProtKB:Q8IWK6] synonym: "UNQ556/PRO1113" EXACT [UniProtKB:Q8IWK6] xref: EMBL:AY181243 xref: EMBL:AY358306 xref: EMBL:BC026009 xref: EMBL:BC035645 xref: HGNC:HGNC:13839 xref: UniGene:Hs.99195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057361 ! GP125_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017965 name: GPR128_human def: "Probable G-protein coupled receptor 128 precursor gene" [UniProtKB:Q96K78] xref: EMBL:AK027360 xref: EMBL:AY181246 xref: HGNC:HGNC:19241 xref: UniGene:Hs.334511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058255 ! GP128_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017966 name: GPR133_human def: "Probable G-protein coupled receptor 133 precursor gene" [UniProtKB:Q6QNK2] synonym: "PGR25" EXACT [UniProtKB:Q6QNK2] xref: EMBL:AK131538 xref: EMBL:AY255587 xref: EMBL:AY278561 xref: EMBL:AY532280 xref: EMBL:BC112307 xref: EMBL:BC112309 xref: HGNC:HGNC:19893 xref: UniGene:Hs.656754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056934 ! GP133_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017967 name: GPR139_human def: "Probable G-protein coupled receptor 139 gene" [UniProtKB:Q6DWJ6] synonym: "GPRG1" EXACT [UniProtKB:Q6DWJ6] synonym: "PGR3" EXACT [UniProtKB:Q6DWJ6] xref: EMBL:AB083594 xref: EMBL:AB196529 xref: EMBL:AY255545 xref: EMBL:AY635179 xref: HGNC:HGNC:19995 xref: UniGene:Hs.446875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056730 ! GP139_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017968 name: GPR141_human def: "Probable G-protein coupled receptor 141 gene" [UniProtKB:Q7Z602] synonym: "PGR13" EXACT [UniProtKB:Q7Z602] xref: EMBL:AY255538 xref: EMBL:AY288420 xref: EMBL:BC120951 xref: EMBL:BC120952 xref: HGNC:HGNC:19997 xref: UniGene:Hs.688230 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057189 ! GP141_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017969 name: GPR142_human def: "Probable G-protein coupled receptor 142 gene" [UniProtKB:Q7Z601] synonym: "PGR2" EXACT [UniProtKB:Q7Z601] xref: EMBL:AB065914 xref: EMBL:AY255622 xref: EMBL:AY288421 xref: HGNC:HGNC:20088 xref: UniGene:Hs.574368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057188 ! GP142_HUMAN relationship: codes_for CCO:B0057638 ! Q8NGB0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017970 name: GPR144_human def: "Probable G-protein coupled receptor 144 gene" [UniProtKB:Q7Z7M1] synonym: "PGR24" EXACT [UniProtKB:Q7Z7M1] xref: EMBL:AB065601 xref: EMBL:AL137846 xref: EMBL:AY255620 xref: EMBL:AY278562 xref: HGNC:HGNC:18651 xref: UniGene:Hs.454099 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057220 ! GP144_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017971 name: GPR146_human def: "Probable G-protein coupled receptor 146 gene" [UniProtKB:Q96CH1] synonym: "PGR8" EXACT [UniProtKB:Q96CH1] xref: EMBL:AY255535 xref: EMBL:BC014241 xref: HGNC:HGNC:21718 xref: UniGene:Hs.585007 xref: UniGene:Hs.656731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058182 ! GP146_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017972 name: GPR148_human def: "Probable G-protein coupled receptor 148 gene" [UniProtKB:Q8TDV2] synonym: "BTR" EXACT [UniProtKB:Q8TDV2] synonym: "PGR6" EXACT [UniProtKB:Q8TDV2] xref: EMBL:AB083589 xref: EMBL:AY255532 xref: EMBL:AY280965 xref: EMBL:AY569570 xref: EMBL:BC105013 xref: EMBL:BC105041 xref: HGNC:HGNC:23623 xref: UniGene:Hs.452574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057943 ! GP148_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017973 name: GPR149_human def: "Probable G-protein coupled receptor 149 gene" [UniProtKB:Q86SP6] synonym: "PGR10" EXACT [UniProtKB:Q86SP6] xref: EMBL:AC092946 xref: EMBL:AY255534 xref: HGNC:HGNC:23627 xref: UniGene:Hs.688231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057231 ! GP149_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017974 name: GPR150_human def: "Probable G-protein coupled receptor 150 gene" [UniProtKB:Q8NGU9] xref: EMBL:AB065678 xref: HGNC:HGNC:23628 xref: UniGene:Hs.143315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057765 ! GP150_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017975 name: GPR151_human def: "Probable G-protein coupled receptor 151 gene" [UniProtKB:Q8TDV0] synonym: "PGR7" EXACT [UniProtKB:Q8TDV0] xref: EMBL:AB065674 xref: EMBL:AB083592 xref: EMBL:AY255557 xref: EMBL:AY351676 xref: HGNC:HGNC:23624 xref: UniGene:Hs.483732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057941 ! GP151_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017976 name: GPR152_human def: "Probable G-protein coupled receptor 152 gene" [UniProtKB:Q8TDT2] synonym: "PGR5" EXACT [UniProtKB:Q8TDT2] xref: EMBL:AB065853 xref: EMBL:AB083620 xref: EMBL:AY255600 xref: EMBL:AY569571 xref: EMBL:BC119779 xref: EMBL:BC122869 xref: HGNC:HGNC:23622 xref: UniGene:Hs.567997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057935 ! GP152_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017977 name: GPR153_human def: "Probable G-protein coupled receptor 153 gene" [UniProtKB:Q6NV75] synonym: "PGR1" EXACT [UniProtKB:Q6NV75] xref: EMBL:AL031847 xref: EMBL:AY255529 xref: EMBL:BC068275 xref: EMBL:CR627473 xref: HGNC:HGNC:23618 xref: UniGene:Hs.531581 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056862 ! GP153_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017978 name: GPR155_human def: "Integral membrane protein GPR155 gene" [UniProtKB:Q7Z3F1] synonym: "PGR22" EXACT [UniProtKB:Q7Z3F1] xref: EMBL:AC010894 xref: EMBL:AC018470 xref: EMBL:AK056381 xref: EMBL:AK091200 xref: EMBL:AK096665 xref: EMBL:AL834154 xref: EMBL:AY255528 xref: EMBL:BC028730 xref: EMBL:BC035037 xref: EMBL:BX537947 xref: HGNC:HGNC:22951 xref: UniGene:Hs.516604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057149 ! GP155_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017979 name: GPR156_human def: "Probable G-protein coupled receptor 156 gene" [UniProtKB:Q8NFN8] synonym: "GABABL" EXACT [UniProtKB:Q8NFN8] synonym: "PGR28" EXACT [UniProtKB:Q8NFN8] xref: EMBL:AF488739 xref: EMBL:AY255565 xref: EMBL:BC113701 xref: HGNC:HGNC:20844 xref: UniGene:Hs.333358 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057606 ! GP156_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017980 name: GPR157_human def: "Probable G-protein coupled receptor 157 gene" [UniProtKB:Q5UAW9] xref: EMBL:AK022194 xref: EMBL:AL158048 xref: EMBL:AY768808 xref: EMBL:BC018691 xref: HGNC:HGNC:23687 xref: UniGene:Hs.632367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056640 ! GP157_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017981 name: GPR158_human def: "Probable G-protein coupled receptor 158 precursor gene" [UniProtKB:Q5T848] synonym: "KIAA1136" EXACT [UniProtKB:Q5T848] xref: EMBL:AB032962 xref: EMBL:AL139821 xref: EMBL:AL161654 xref: EMBL:AL355587 xref: EMBL:AY528411 xref: HGNC:HGNC:23689 xref: UniGene:Hs.499108 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056596 ! GP158_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017982 name: GPR160_human def: "Probable G-protein coupled receptor 160 gene" [UniProtKB:Q9UJ42] synonym: "GPCR150" EXACT [UniProtKB:Q9UJ42] xref: EMBL:AB083583 xref: EMBL:AJ249248 xref: EMBL:BC000181 xref: HGNC:HGNC:23693 xref: UniGene:Hs.231320 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059168 ! GP160_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017983 name: GPR161_human def: "Probable G-protein coupled receptor 161 gene" [UniProtKB:Q8N6U8] xref: EMBL:AF091890 xref: EMBL:AK056040 xref: EMBL:AL033532 xref: EMBL:AY275468 xref: EMBL:BC028163 xref: HGNC:HGNC:23694 xref: UniGene:Hs.271809 xref: UniGene:Hs.632453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057494 ! GP161_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017984 name: GPR162_human def: "Probable G-protein coupled receptor 162 gene" [UniProtKB:Q16538] synonym: "GRCA" EXACT [UniProtKB:Q16538] xref: EMBL:AB209836 xref: EMBL:BC002353 xref: EMBL:BC080585 xref: EMBL:U47924 xref: EMBL:U47925 xref: EMBL:U47928 xref: HGNC:HGNC:16693 xref: UniGene:Hs.631654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056146 ! GP162_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017985 name: GPR171_human def: "Probable G-protein coupled receptor 171 gene" [UniProtKB:O14626] synonym: "H963" EXACT [UniProtKB:O14626] xref: EMBL:AF002986 xref: EMBL:AF411849 xref: HGNC:HGNC:30057 xref: UniGene:Hs.549152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054360 ! GP171_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017986 name: GPR173_human def: "Probable G-protein coupled receptor 173 gene" [UniProtKB:Q9NS66] synonym: "SREB3" EXACT [UniProtKB:Q9NS66] xref: EMBL:AB040801 xref: EMBL:BC009861 xref: EMBL:BX322635 xref: EMBL:CH471154 xref: HGNC:HGNC:18186 xref: UniGene:Hs.661815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054282 ! B1B0A5_HUMAN relationship: codes_for CCO:B0058909 ! GP173_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017987 name: GPR174_human def: "Probable G-protein coupled receptor 174 gene" [UniProtKB:Q9BXC1] synonym: "FKSG79" EXACT [UniProtKB:Q9BXC1] xref: EMBL:AB083599 xref: EMBL:AF345567 xref: EMBL:AL590222 xref: EMBL:AY242133 xref: EMBL:BC104922 xref: EMBL:BC104924 xref: HGNC:HGNC:30245 xref: UniGene:Hs.326713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058550 ! GP174_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017988 name: GPR176_human def: "Probable G-protein coupled receptor 176 gene" [UniProtKB:Q14439] xref: EMBL:BC067106 xref: EMBL:D38449 xref: HGNC:HGNC:32370 xref: UniGene:Hs.37196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055983 ! GP176_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017989 name: GPR177_human def: "Integral membrane protein GPR177 precursor gene" [UniProtKB:Q5T9L3] synonym: "C1orf139" EXACT [UniProtKB:Q5T9L3] synonym: "UNQ85/PRO18667" EXACT [UniProtKB:Q5T9L3] synonym: "WLS" EXACT [UniProtKB:Q5T9L3] xref: EMBL:AK074984 xref: EMBL:AL157407 xref: EMBL:AL513284 xref: EMBL:AY359035 xref: EMBL:BC110826 xref: EMBL:BX538320 xref: EMBL:DQ323735 xref: HGNC:HGNC:30238 xref: UniGene:Hs.647659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056601 ! GP177_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017990 name: GPR182_human def: "G-protein coupled receptor 182 gene" [UniProtKB:O15218] synonym: "ADMR" EXACT [UniProtKB:O15218] xref: EMBL:AY268434 xref: EMBL:BC034761 xref: EMBL:Y13583 xref: HGNC:HGNC:13708 xref: UniGene:Hs.483909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054417 ! GP182_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017991 name: GP1BB_human def: "Platelet glycoprotein Ib beta chain precursor gene" [UniProtKB:P13224] xref: EMBL:AB086231 xref: EMBL:AF006988 xref: EMBL:J03259 xref: EMBL:L20860 xref: EMBL:U59632 xref: HGNC:HGNC:4440 xref: UniGene:Hs.283743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055010 ! GP1BB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017992 name: GPBAR1_human def: "G-protein coupled bile acid receptor 1 gene" [UniProtKB:Q8TDU6] synonym: "TGR5" EXACT [UniProtKB:Q8TDU6] xref: EMBL:AB083601 xref: EMBL:AB086170 xref: EMBL:AB089307 xref: EMBL:BC033625 xref: HGNC:HGNC:19680 xref: UniGene:Hs.160954 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057939 ! GPBAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017993 name: GPBP1L1_human def: "Vasculin-like protein 1 gene" [UniProtKB:Q9HC44] synonym: "SP192" EXACT [UniProtKB:Q9HC44] xref: EMBL:AF177334 xref: EMBL:AK024972 xref: EMBL:AL604028 xref: EMBL:AL834194 xref: EMBL:BC015713 xref: EMBL:BC022218 xref: EMBL:BC052257 xref: EMBL:CH471059 xref: HGNC:HGNC:28843 xref: UniGene:Hs.238432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058796 ! GPBL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017994 name: GPBP1_human def: "Vasculin gene" [UniProtKB:Q86WP2] synonym: "GPBP" EXACT [UniProtKB:Q86WP2] synonym: "SSH6" EXACT [UniProtKB:Q86WP2] xref: EMBL:AC034244 xref: EMBL:AK024807 xref: EMBL:AL136844 xref: EMBL:AL161991 xref: EMBL:AY226828 xref: EMBL:BC000267 xref: EMBL:BC070132 xref: EMBL:BC113004 xref: EMBL:CH471123 xref: HGNC:HGNC:29520 xref: UniGene:Hs.444279 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057278 ! GPBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017995 name: GPC4_human def: "Glypican-4 precursor gene" [UniProtKB:O75487] synonym: "UNQ474/PRO937" EXACT [UniProtKB:O75487] xref: EMBL:AF030186 xref: EMBL:AF064826 xref: EMBL:AL034400 xref: EMBL:AL109623 xref: EMBL:AY052833 xref: EMBL:AY358507 xref: EMBL:BC017166 xref: HGNC:HGNC:4452 xref: UniGene:Hs.58367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054643 ! GPC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017996 name: GPRC5B_human def: "G-protein coupled receptor family C group 5 member B precursor gene" [UniProtKB:Q9NZH0] synonym: "RAIG2" EXACT [UniProtKB:Q9NZH0] xref: EMBL:AC004131 xref: EMBL:AF181862 xref: EMBL:AF202640 xref: EMBL:AJ276101 xref: EMBL:AK075119 xref: EMBL:BC034467 xref: HGNC:HGNC:13308 xref: UniGene:Hs.148685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058996 ! GPC5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017997 name: GPRC5C_human def: "G-protein coupled receptor family C group 5 member C precursor gene" [UniProtKB:Q9NQ84] synonym: "PSEC0087" EXACT [UniProtKB:Q9NQ84] synonym: "RAIG3" EXACT [UniProtKB:Q9NQ84] xref: EMBL:AC079325 xref: EMBL:AF207989 xref: EMBL:AJ276102 xref: EMBL:AK075397 xref: EMBL:AK131210 xref: EMBL:BC016860 xref: EMBL:BC110848 xref: EMBL:BC125080 xref: EMBL:BC125081 xref: EMBL:BT007435 xref: HGNC:HGNC:13309 xref: UniGene:Hs.446438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054109 ! A8MXZ4_HUMAN relationship: codes_for CCO:B0056219 ! Q2NL85_HUMAN relationship: codes_for CCO:B0058864 ! GPC5C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017998 name: GPRC5D_human def: "G-protein coupled receptor family C group 5 member D gene" [UniProtKB:Q9NZD1] xref: EMBL:AB083629 xref: EMBL:AB099817 xref: EMBL:AF209923 xref: EMBL:BC069341 xref: EMBL:BC107077 xref: EMBL:BC107078 xref: HGNC:HGNC:13310 xref: UniGene:Hs.644599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058993 ! GPC5D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0017999 name: GPRC6A_human def: "G-protein coupled receptor family C group 6 member A precursor gene" [UniProtKB:Q5T6X5] synonym: "GPCR33" EXACT [UniProtKB:Q5T6X5] xref: EMBL:AB065680 xref: EMBL:AB083615 xref: EMBL:AF502962 xref: EMBL:AL354716 xref: EMBL:AY435125 xref: EMBL:AY435126 xref: EMBL:AY435127 xref: HGNC:HGNC:18510 xref: UniGene:Hs.675164 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056592 ! GPC6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018000 name: GPER_human def: "G-protein coupled estrogen receptor 1 gene" [UniProtKB:Q99527] synonym: "CEPR" EXACT [UniProtKB:Q99527] synonym: "CMKRL2" EXACT [UniProtKB:Q99527] synonym: "DRY12" EXACT [UniProtKB:Q99527] synonym: "GPR30" EXACT [UniProtKB:Q99527] xref: EMBL:AF015257 xref: EMBL:AF027956 xref: EMBL:BC011634 xref: EMBL:BC082766 xref: EMBL:CH236953 xref: EMBL:CR541741 xref: EMBL:U58828 xref: EMBL:U63917 xref: EMBL:U77827 xref: EMBL:X98510 xref: EMBL:Y08162 xref: HGNC:HGNC:4485 xref: UniGene:Hs.20961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056691 ! Q63ZY2_HUMAN relationship: codes_for CCO:B0058422 ! GPER_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018001 name: GPNMB_human def: "Transmembrane glycoprotein NMB precursor gene" [UniProtKB:Q14956] synonym: "HGFIN" EXACT [UniProtKB:Q14956] synonym: "NMB" EXACT [UniProtKB:Q14956] synonym: "UNQ1725/PRO9925" EXACT [UniProtKB:Q14956] xref: EMBL:AC005082 xref: EMBL:AF322909 xref: EMBL:AY359124 xref: EMBL:BC032783 xref: EMBL:X76534 xref: HGNC:HGNC:4462 xref: UniGene:Hs.190495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056027 ! GPNMB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018002 name: GPR12_human def: "Probable G-protein coupled receptor 12 gene" [UniProtKB:P47775] xref: EMBL:AL159978 xref: EMBL:BC067448 xref: EMBL:BC067452 xref: EMBL:BC112144 xref: EMBL:BC112146 xref: EMBL:U18548 xref: HGNC:HGNC:4466 xref: UniGene:Hs.123034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055385 ! GPR12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018003 name: GPR15_human def: "G-protein coupled receptor 15 gene" [UniProtKB:P49685] xref: EMBL:BC069437 xref: EMBL:BC101779 xref: EMBL:BC101781 xref: EMBL:U34806 xref: HGNC:HGNC:4469 xref: UniGene:Hs.563128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055430 ! GPR15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018004 name: GPR17_human def: "Uracil nucleotide/cysteinyl leukotriene receptor gene" [UniProtKB:Q13304] xref: EMBL:BC031653 xref: EMBL:BC039595 xref: EMBL:U33447 xref: EMBL:Y12546 xref: EMBL:Z94154 xref: EMBL:Z94155 xref: HGNC:HGNC:4471 xref: UniGene:Hs.46453 xref: UniGene:Hs.688940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055895 ! GPR17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018005 name: GPR18_human def: "N-arachidonyl glycine receptor gene" [UniProtKB:Q14330] synonym: "GPCRW" EXACT [UniProtKB:Q14330] xref: EMBL:AF261135 xref: EMBL:AL160155 xref: EMBL:BC008569 xref: EMBL:BC050646 xref: EMBL:BC066927 xref: EMBL:BT009907 xref: EMBL:L42324 xref: HGNC:HGNC:4472 xref: UniGene:Hs.631765 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055979 ! GPR18_HUMAN relationship: codes_for CCO:B0056488 ! Q5JUH9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018006 name: GPR19_human def: "Probable G-protein coupled receptor 19 gene" [UniProtKB:Q15760] xref: EMBL:U55312 xref: EMBL:U64871 xref: HGNC:HGNC:4473 xref: UniGene:Hs.657862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056104 ! GPR19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018007 name: GPR1_human def: "Probable G-protein coupled receptor 1 gene" [UniProtKB:P46091] xref: EMBL:AC007383 xref: EMBL:BC058005 xref: EMBL:BC067833 xref: EMBL:U13666 xref: HGNC:HGNC:4463 xref: UniGene:Hs.184907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055373 ! GPR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018008 name: GPR20_human def: "Probable G-protein coupled receptor 20 gene" [UniProtKB:Q99678] xref: EMBL:BC117409 xref: EMBL:CH471060 xref: EMBL:U66579 xref: HGNC:HGNC:4475 xref: UniGene:Hs.188859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056182 ! Q17R96_HUMAN relationship: codes_for CCO:B0058438 ! GPR20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018009 name: GPR21_human def: "Probable G-protein coupled receptor 21 gene" [UniProtKB:Q99679] xref: EMBL:BC066885 xref: EMBL:BC066886 xref: EMBL:BC067532 xref: EMBL:BC067533 xref: EMBL:U66580 xref: HGNC:HGNC:4476 xref: UniGene:Hs.656648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058439 ! GPR21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018010 name: GPR22_human def: "Probable G-protein coupled receptor 22 gene" [UniProtKB:Q99680] xref: EMBL:AC002381 xref: EMBL:U66581 xref: HGNC:HGNC:4477 xref: UniGene:Hs.657277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058440 ! GPR22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018011 name: GPR25_human def: "Probable G-protein coupled receptor 25 gene" [UniProtKB:O00155] xref: EMBL:BC126386 xref: EMBL:BC126388 xref: EMBL:U91939 xref: HGNC:HGNC:4480 xref: UniGene:Hs.534316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054291 ! GPR25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018012 name: GPR26_human def: "Probable G-protein coupled receptor 26 gene" [UniProtKB:Q8NDV2] xref: EMBL:AJ505757 xref: EMBL:BC112011 xref: EMBL:BC113462 xref: HGNC:HGNC:4481 xref: UniGene:Hs.12751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057581 ! GPR26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018013 name: GPR27_human def: "Probable G-protein coupled receptor 27 gene" [UniProtKB:Q9NS67] synonym: "SREB1" EXACT [UniProtKB:Q9NS67] xref: EMBL:AB040799 xref: HGNC:HGNC:4482 xref: UniGene:Hs.591653 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058910 ! GPR27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018014 name: GPR31_human def: "Probable G-protein coupled receptor 31 gene" [UniProtKB:O00270] xref: EMBL:AL121935 xref: EMBL:U65402 xref: HGNC:HGNC:4486 xref: UniGene:Hs.248124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054306 ! GPR31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018015 name: GPR32_human def: "Probable G-protein coupled receptor 32 gene" [UniProtKB:O75388] xref: EMBL:AF045764 xref: EMBL:BC067453 xref: EMBL:BC067454 xref: EMBL:BC095544 xref: HGNC:HGNC:4487 xref: UniGene:Hs.515555 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054630 ! GPR32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018016 name: GPR33_human def: "Probable G-protein coupled receptor 33 gene" [UniProtKB:Q49SQ1] xref: EMBL:AY494000 xref: HGNC:HGNC:4489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056308 ! GPR33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018017 name: GPR34_human def: "Probable G-protein coupled receptor 34 gene" [UniProtKB:Q9UPC5] xref: EMBL:AF039686 xref: EMBL:AF118670 xref: EMBL:AK027780 xref: EMBL:AL627402 xref: EMBL:BC020678 xref: EMBL:CH471141 xref: EMBL:DQ106398 xref: EMBL:DQ106399 xref: EMBL:DQ106400 xref: EMBL:DQ106401 xref: HGNC:HGNC:4490 xref: UniGene:Hs.495989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056266 ! Q3SAH2_HUMAN relationship: codes_for CCO:B0056645 ! Q5VT14_HUMAN relationship: codes_for CCO:B0059259 ! GPR34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018018 name: GPR37_human def: "Probable G-protein coupled receptor 37 precursor gene" [UniProtKB:O15354] xref: EMBL:AC004925 xref: EMBL:AF017262 xref: EMBL:AF502281 xref: EMBL:BC040007 xref: EMBL:U87460 xref: EMBL:Y12476 xref: EMBL:Y12477 xref: HGNC:HGNC:4494 xref: UniGene:Hs.406094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054432 ! GPR37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018019 name: GPR39_human def: "Probable G-protein coupled receptor 39 gene" [UniProtKB:O43194] xref: EMBL:AC079773 xref: EMBL:AC098800 xref: EMBL:AF034633 xref: EMBL:BC125046 xref: HGNC:HGNC:4496 xref: UniGene:Hs.432395 xref: UniGene:Hs.694844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054460 ! GPR39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018020 name: GPR3_human def: "Probable G-protein coupled receptor 3 gene" [UniProtKB:P46089] synonym: "ACCA" EXACT [UniProtKB:P46089] xref: EMBL:AL096774 xref: EMBL:BC032702 xref: EMBL:L32831 xref: EMBL:U13668 xref: EMBL:U18550 xref: EMBL:X83956 xref: HGNC:HGNC:4484 xref: UniGene:Hs.66542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055372 ! GPR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018021 name: GPR42P_human def: "Putative G-protein coupled receptor 42 gene" [UniProtKB:O15529] synonym: "GPR42" EXACT [UniProtKB:O15529] xref: EMBL:AC002511 xref: EMBL:AF024689 xref: HGNC:HGNC:4500 xref: UniGene:Hs.533926 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054444 ! GPR42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018022 name: GPR44_human def: "Putative G-protein coupled receptor 44 gene" [UniProtKB:Q9Y5Y4] synonym: "CRTH2" EXACT [UniProtKB:Q9Y5Y4] synonym: "DL1R" EXACT [UniProtKB:Q9Y5Y4] xref: EMBL:AB008535 xref: EMBL:AF118265 xref: EMBL:AF144308 xref: EMBL:AY507142 xref: EMBL:BC096841 xref: HGNC:HGNC:4502 xref: UniGene:Hs.299567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059393 ! GPR44_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018023 name: GPR4_human def: "Probable G-protein coupled receptor 4 gene" [UniProtKB:P46093] synonym: "GPR19" EXACT [UniProtKB:P46093] xref: EMBL:BC067536 xref: EMBL:L36148 xref: EMBL:U21051 xref: EMBL:U35399 xref: HGNC:HGNC:4497 xref: UniGene:Hs.17170 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024308 ! GPR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018024 name: GPR52_human def: "Probable G-protein coupled receptor 52 gene" [UniProtKB:Q9Y2T5] xref: EMBL:AF096784 xref: EMBL:AL022171 xref: EMBL:BC067456 xref: EMBL:BC067457 xref: EMBL:BC067458 xref: EMBL:BC067459 xref: EMBL:BC067460 xref: EMBL:BC069460 xref: EMBL:BC095532 xref: HGNC:HGNC:4508 xref: UniGene:Hs.673850 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059316 ! GPR52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018025 name: GPR55_human def: "Probable G-protein coupled receptor 55 gene" [UniProtKB:Q9Y2T6] xref: EMBL:AF096786 xref: EMBL:BC032694 xref: EMBL:CR541776 xref: HGNC:HGNC:4511 xref: UniGene:Hs.114545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059317 ! GPR55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018026 name: GPR56_human def: "G-protein coupled receptor 56 precursor gene" [UniProtKB:Q9Y653] synonym: "TM7LN4" EXACT [UniProtKB:Q9Y653] synonym: "TM7XN1" EXACT [UniProtKB:Q9Y653] synonym: "UNQ540/PRO1083" EXACT [UniProtKB:Q9Y653] xref: EMBL:AB065909 xref: EMBL:AC018552 xref: EMBL:AF106858 xref: EMBL:AJ011001 xref: EMBL:AY358400 xref: EMBL:BC008770 xref: EMBL:BT007311 xref: EMBL:CH471092 xref: HGNC:HGNC:4512 xref: UniGene:Hs.513633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059397 ! GPR56_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018027 name: GPR61_human def: "Probable G-protein coupled receptor 61 gene" [UniProtKB:Q9BZJ8] synonym: "BALGR" EXACT [UniProtKB:Q9BZJ8] xref: EMBL:AB083585 xref: EMBL:AF258342 xref: EMBL:AF317652 xref: EMBL:AL355310 xref: EMBL:BC067464 xref: HGNC:HGNC:13300 xref: UniGene:Hs.514690 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058602 ! GPR61_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018028 name: GPR62_human def: "Probable G-protein coupled receptor 62 gene" [UniProtKB:Q9BZJ7] xref: EMBL:AB083590 xref: EMBL:AF317653 xref: HGNC:HGNC:13301 xref: UniGene:Hs.232213 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058601 ! GPR62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018029 name: GPR63_human def: "Probable G-protein coupled receptor 63 gene" [UniProtKB:Q9BZJ6] synonym: "PSP24B" EXACT [UniProtKB:Q9BZJ6] xref: EMBL:AB030566 xref: EMBL:AF317654 xref: EMBL:AL033379 xref: EMBL:BC067465 xref: EMBL:BC067469 xref: HGNC:HGNC:13302 xref: UniGene:Hs.632612 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058600 ! GPR63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018030 name: GPR6_human def: "Sphingosine 1-phosphate receptor GPR6 gene" [UniProtKB:P46095] xref: EMBL:AL591076 xref: EMBL:BC043414 xref: EMBL:BC117298 xref: EMBL:BC126301 xref: EMBL:L36150 xref: EMBL:U18549 xref: HGNC:HGNC:4515 xref: UniGene:Hs.46332 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055375 ! GPR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018031 name: GPR75_human def: "Probable G-protein coupled receptor 75 gene" [UniProtKB:O95800] xref: EMBL:AC008068 xref: EMBL:AF072693 xref: EMBL:AF101472 xref: EMBL:BC067475 xref: EMBL:BC067476 xref: HGNC:HGNC:4526 xref: UniGene:Hs.696596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054794 ! GPR75_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018032 name: GPR78_human def: "Probable G-protein coupled receptor 78 gene" [UniProtKB:Q96P69] synonym: "UNQ5925/PRO19818" EXACT [UniProtKB:Q96P69] xref: EMBL:AB065673 xref: EMBL:AF411107 xref: EMBL:AY359107 xref: EMBL:BC057778 xref: EMBL:BC069343 xref: EMBL:BC069813 xref: HGNC:HGNC:4528 xref: UniGene:Hs.350588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058324 ! GPR78_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018033 name: GPR81_human def: "Probable G-protein coupled receptor 81 gene" [UniProtKB:Q9BXC0] synonym: "FKSG80" EXACT [UniProtKB:Q9BXC0] synonym: "GPR104" EXACT [UniProtKB:Q9BXC0] xref: EMBL:AB065866 xref: EMBL:AB083631 xref: EMBL:AF345568 xref: EMBL:AF411110 xref: EMBL:AY507143 xref: EMBL:BC066881 xref: EMBL:BC066882 xref: EMBL:BC066883 xref: EMBL:BC067484 xref: EMBL:DQ157221 xref: HGNC:HGNC:4532 xref: UniGene:Hs.458425 xref: UniGene:Hs.610873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058549 ! GPR81_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018034 name: GPR82_human def: "Probable G-protein coupled receptor 82 gene" [UniProtKB:Q96P67] xref: EMBL:AB065935 xref: EMBL:AB083595 xref: EMBL:AF411111 xref: EMBL:AJ319076 xref: EMBL:AK122626 xref: EMBL:AK313702 xref: EMBL:AL627402 xref: EMBL:BC070180 xref: EMBL:CH471141 xref: HGNC:HGNC:4533 xref: UniGene:Hs.664795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056644 ! Q5VT13_HUMAN relationship: codes_for CCO:B0058322 ! GPR82_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018035 name: GPR83_human def: "Probable G-protein coupled receptor 83 precursor gene" [UniProtKB:Q9NYM4] synonym: "GPR72" EXACT [UniProtKB:Q9NYM4] synonym: "KIAA1540" EXACT [UniProtKB:Q9NYM4] xref: EMBL:AB040973 xref: EMBL:AF236081 xref: EMBL:AK315161 xref: EMBL:BC067473 xref: EMBL:BC067474 xref: EMBL:CH471065 xref: HGNC:HGNC:4523 xref: UniGene:Hs.272385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056864 ! Q6NWR3_HUMAN relationship: codes_for CCO:B0058965 ! GPR83_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018036 name: GPR84_human def: "Probable G-protein coupled receptor 84 gene" [UniProtKB:Q9NQS5] synonym: "EX33" EXACT [UniProtKB:Q9NQS5] xref: EMBL:AB083586 xref: EMBL:AF237762 xref: EMBL:AF282693 xref: EMBL:BC020614 xref: HGNC:HGNC:4535 xref: UniGene:Hs.306199 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058872 ! GPR84_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018037 name: GPR85_human def: "Probable G-protein coupled receptor 85 gene" [UniProtKB:P60893] synonym: "SREB2" EXACT [UniProtKB:P60893] xref: EMBL:AB040800 xref: EMBL:AB065688 xref: EMBL:AC073346 xref: EMBL:AF250237 xref: EMBL:AL161959 xref: HGNC:HGNC:4536 xref: UniGene:Hs.152009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055599 ! GPR85_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018038 name: GPR87_human def: "Probable G-protein coupled receptor 87 gene" [UniProtKB:Q9BY21] synonym: "FKSG78" EXACT [UniProtKB:Q9BY21] synonym: "GPR95" EXACT [UniProtKB:Q9BY21] xref: EMBL:AF237763 xref: EMBL:AF345566 xref: EMBL:AF411114 xref: EMBL:AK027784 xref: EMBL:BC009540 xref: HGNC:HGNC:4538 xref: UniGene:Hs.591292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058567 ! GPR87_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018039 name: GPR88_human def: "Probable G-protein coupled receptor 88 gene" [UniProtKB:Q9GZN0] synonym: "STRG" EXACT [UniProtKB:Q9GZN0] xref: EMBL:AB042410 xref: EMBL:AB042411 xref: EMBL:AY336999 xref: HGNC:HGNC:4539 xref: UniGene:Hs.170053 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058629 ! GPR88_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018040 name: GPR89A_human def: "Protein GPR89 gene" [UniProtKB:Q9Y302] synonym: "CGI-13" EXACT [UniProtKB:Q9Y302] synonym: "GPR89" EXACT [UniProtKB:Q9Y302] synonym: "HSPC201" EXACT [UniProtKB:Q9Y302] synonym: "SH120" EXACT [UniProtKB:Q9Y302] synonym: "UNQ192/PRO218" EXACT [UniProtKB:Q9Y302] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059327 ! GPR89_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018041 name: GPR89B_human def: "Protein GPR89 gene" [UniProtKB:Q9Y302] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059327 ! GPR89_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018042 name: GPR97_human def: "Probable G-protein coupled receptor 97 precursor gene" [UniProtKB:Q86Y34] synonym: "PGR26" EXACT [UniProtKB:Q86Y34] xref: EMBL:AB049169 xref: EMBL:AK172801 xref: EMBL:AY140959 xref: EMBL:AY255601 xref: EMBL:BC064508 xref: HGNC:HGNC:13728 xref: UniGene:Hs.383403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057300 ! GPR97_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018043 name: GPR98_human def: "G-protein coupled receptor 98 precursor gene" [UniProtKB:Q8WXG9] synonym: "KIAA0686" EXACT [UniProtKB:Q8WXG9] synonym: "KIAA1943" EXACT [UniProtKB:Q8WXG9] synonym: "MASS1" EXACT [UniProtKB:Q8WXG9] synonym: "VLGR1" EXACT [UniProtKB:Q8WXG9] xref: EMBL:AB014586 xref: EMBL:AB075823 xref: EMBL:AF055084 xref: EMBL:AF435925 xref: EMBL:AL136541 xref: HGNC:HGNC:17416 xref: UniGene:Hs.591777 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058018 ! GPR98_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018044 name: GPSM1_human def: "G-protein-signaling modulator 1 gene" [UniProtKB:Q86YR5] synonym: "AGS3" EXACT [UniProtKB:Q86YR5] xref: EMBL:AL117478 xref: EMBL:AY173053 xref: EMBL:BC009979 xref: EMBL:BC017353 xref: EMBL:BC048343 xref: EMBL:BX649589 xref: EMBL:CH471090 xref: HGNC:HGNC:17858 xref: UniGene:Hs.239370 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057309 ! GPSM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018045 name: GPSM3_human def: "G-protein-signaling modulator 3 gene" [UniProtKB:Q9Y4H4] synonym: "AGS4" EXACT [UniProtKB:Q9Y4H4] synonym: "C6orf9" EXACT [UniProtKB:Q9Y4H4] synonym: "G18" EXACT [UniProtKB:Q9Y4H4] xref: EMBL:AF155657 xref: EMBL:AJ243937 xref: EMBL:AL662830 xref: EMBL:AL662884 xref: EMBL:AL845464 xref: EMBL:BC018724 xref: HGNC:HGNC:13945 xref: UniGene:Hs.520046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059363 ! GPSM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018046 name: GP6_human def: "Platelet glycoprotein VI precursor gene" [UniProtKB:Q9HCN6] synonym: "GPVI" EXACT [UniProtKB:Q9HCN6] xref: EMBL:AB035073 xref: EMBL:AB043819 xref: EMBL:AB043820 xref: EMBL:AB043821 xref: EMBL:AC011476 xref: EMBL:BC104832 xref: EMBL:BC111963 xref: HGNC:HGNC:14388 xref: UniGene:Hs.661752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058814 ! GPVI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018047 name: GPX1_human def: "Glutathione peroxidase 1 gene" [UniProtKB:P07203] xref: EMBL:AY327818 xref: EMBL:BC000742 xref: EMBL:M21304 xref: EMBL:M83094 xref: EMBL:X13709 xref: EMBL:X13710 xref: EMBL:Y00433 xref: EMBL:Y00483 xref: HGNC:HGNC:4553 xref: UniGene:Hs.76686 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054910 ! GPX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018048 name: GZMA_human def: "Granzyme A precursor gene" [UniProtKB:P12544] synonym: "CTLA3" EXACT [UniProtKB:P12544] synonym: "HFSP" EXACT [UniProtKB:P12544] xref: EMBL:BC015739 xref: EMBL:CR456968 xref: EMBL:M18737 xref: EMBL:U40006 xref: HGNC:HGNC:4708 xref: UniGene:Hs.90708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055002 ! GRAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018049 name: GZMB_human def: "Granzyme B precursor gene" [UniProtKB:P10144] synonym: "CGL1" EXACT [UniProtKB:P10144] synonym: "CSPB" EXACT [UniProtKB:P10144] synonym: "CTLA1" EXACT [UniProtKB:P10144] synonym: "GRB" EXACT [UniProtKB:P10144] xref: EMBL:AL136018 xref: EMBL:BC030195 xref: EMBL:J03072 xref: EMBL:J03189 xref: EMBL:J04071 xref: EMBL:M17016 xref: EMBL:M28879 xref: EMBL:M38193 xref: HGNC:HGNC:4709 xref: UniGene:Hs.1051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054971 ! GRAB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018050 name: GRAP2_human def: "GRB2-related adapter protein 2 gene" [UniProtKB:O75791] synonym: "GADS" EXACT [UniProtKB:O75791] synonym: "GRB2L" EXACT [UniProtKB:O75791] synonym: "GRID" EXACT [UniProtKB:O75791] xref: EMBL:AF042380 xref: EMBL:AF090456 xref: EMBL:AF102694 xref: EMBL:AF121002 xref: EMBL:AF129476 xref: EMBL:AF236120 xref: EMBL:AJ011736 xref: EMBL:AY069959 xref: EMBL:BC025692 xref: EMBL:BC026002 xref: EMBL:CR456498 xref: EMBL:Y18051 xref: EMBL:Z82206 xref: HGNC:HGNC:4563 xref: UniGene:Hs.517499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054668 ! GRAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018051 name: GRAP_human def: "GRB2-related adapter protein gene" [UniProtKB:Q13588] xref: EMBL:BC035856 xref: EMBL:BC063035 xref: EMBL:BT019981 xref: EMBL:CR541941 xref: EMBL:CR541966 xref: EMBL:U52518 xref: HGNC:HGNC:4562 xref: UniGene:Hs.567416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055933 ! GRAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018052 name: GRB10_human def: "Growth factor receptor-bound protein 10 gene" [UniProtKB:Q13322] synonym: "GRBIR" EXACT [UniProtKB:Q13322] synonym: "KIAA0207" EXACT [UniProtKB:Q13322] xref: EMBL:AC005153 xref: EMBL:AF000017 xref: EMBL:AF001534 xref: EMBL:AF073363 xref: EMBL:AF073364 xref: EMBL:AF073365 xref: EMBL:AF073366 xref: EMBL:AF073367 xref: EMBL:AF073368 xref: EMBL:AF073369 xref: EMBL:AF073370 xref: EMBL:AF073371 xref: EMBL:AF073372 xref: EMBL:AF073373 xref: EMBL:AF073374 xref: EMBL:AF073375 xref: EMBL:AF073376 xref: EMBL:AF073377 xref: EMBL:AF073378 xref: EMBL:AJ271366 xref: EMBL:BC024285 xref: EMBL:CH236955 xref: EMBL:CH471128 xref: EMBL:D86962 xref: EMBL:U34355 xref: EMBL:U66065 xref: EMBL:U69276 xref: HGNC:HGNC:4564 xref: UniGene:Hs.164060 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053755 ! A4D258_HUMAN relationship: codes_for CCO:B0055897 ! GRB10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018053 name: GRB14_human def: "Growth factor receptor-bound protein 14 gene" [UniProtKB:Q14449] xref: EMBL:BC053559 xref: EMBL:L76687 xref: HGNC:HGNC:4565 xref: UniGene:Hs.411881 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055984 ! GRB14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018054 name: GRB7_human def: "Growth factor receptor-bound protein 7 gene" [UniProtKB:Q14451] xref: EMBL:AB008789 xref: EMBL:AB008790 xref: EMBL:AF274875 xref: EMBL:BC006535 xref: EMBL:D43772 xref: EMBL:D87513 xref: HGNC:HGNC:4567 xref: UniGene:Hs.86859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055985 ! GRB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018055 name: CCDC88A_human def: "Girdin gene" [UniProtKB:Q3V6T2] synonym: "APE" EXACT [UniProtKB:Q3V6T2] synonym: "GRDN" EXACT [UniProtKB:Q3V6T2] synonym: "KIAA1212" EXACT [UniProtKB:Q3V6T2] xref: EMBL:AB125644 xref: EMBL:AB201172 xref: EMBL:AC012358 xref: EMBL:AC019198 xref: EMBL:AC092176 xref: EMBL:BC132736 xref: EMBL:BX537985 xref: EMBL:BX538154 xref: EMBL:BX648138 xref: HGNC:HGNC:25523 xref: UniGene:Hs.292925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056278 ! GRDN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018056 name: GREM2_human def: "Gremlin-2 precursor gene" [UniProtKB:Q9H772] synonym: "CKTSF1B2" EXACT [UniProtKB:Q9H772] synonym: "DAND3" EXACT [UniProtKB:Q9H772] synonym: "PRDC" EXACT [UniProtKB:Q9H772] xref: EMBL:AK024848 xref: EMBL:AL358176 xref: EMBL:BC046632 xref: HGNC:HGNC:17655 xref: UniGene:Hs.98206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058739 ! GREM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018057 name: GRHL1_human def: "Grainyhead-like protein 1 homolog gene" [UniProtKB:Q9NZI5] synonym: "LBP32" EXACT [UniProtKB:Q9NZI5] synonym: "MGR" EXACT [UniProtKB:Q9NZI5] synonym: "TFCP2L2" EXACT [UniProtKB:Q9NZI5] xref: EMBL:AC010969 xref: EMBL:AF198489 xref: EMBL:AF411210 xref: EMBL:BC067519 xref: EMBL:BC067520 xref: EMBL:BC067521 xref: HGNC:HGNC:17923 xref: UniGene:Hs.418493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058997 ! GRHL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018058 name: GRHL2_human def: "Grainyhead-like protein 2 homolog gene" [UniProtKB:Q6ISB3] synonym: "BOM" EXACT [UniProtKB:Q6ISB3] synonym: "TFCP2L3" EXACT [UniProtKB:Q6ISB3] xref: EMBL:AK023844 xref: EMBL:BC069618 xref: EMBL:BC069633 xref: EMBL:BC069638 xref: HGNC:HGNC:2799 xref: UniGene:Hs.661088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056828 ! GRHL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018059 name: GRHL3_human def: "Grainyhead-like protein 3 homolog gene" [UniProtKB:Q8TE85] synonym: "SOM" EXACT [UniProtKB:Q8TE85] synonym: "TFCP2L4" EXACT [UniProtKB:Q8TE85] xref: EMBL:AK074386 xref: EMBL:AL031431 xref: EMBL:AL138902 xref: EMBL:AY231160 xref: EMBL:AY231161 xref: EMBL:BC036890 xref: HGNC:HGNC:25839 xref: UniGene:Hs.657920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057951 ! GRHL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018060 name: GRIA1_human def: "Glutamate receptor 1 precursor gene" [UniProtKB:P42261] synonym: "GLUH1" EXACT [UniProtKB:P42261] synonym: "GLUR1" EXACT [UniProtKB:P42261] xref: EMBL:BC111734 xref: EMBL:M64752 xref: EMBL:M81886 xref: EMBL:X58633 xref: HGNC:HGNC:4571 xref: UniGene:Hs.519693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020627 ! GRIA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018061 name: GRIA2_human def: "Glutamate receptor 2 precursor gene" [UniProtKB:P42262] synonym: "GLUR2" EXACT [UniProtKB:P42262] xref: EMBL:BC010574 xref: EMBL:L20814 xref: HGNC:HGNC:4572 xref: UniGene:Hs.32763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020601 ! GRIA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018062 name: GRIA3_human def: "Glutamate receptor 3 precursor gene" [UniProtKB:P42263] synonym: "GLUR3" EXACT [UniProtKB:P42263] synonym: "GLURC" EXACT [UniProtKB:P42263] xref: EMBL:AF166362 xref: EMBL:AF166363 xref: EMBL:AF166364 xref: EMBL:AF166365 xref: EMBL:AF166366 xref: EMBL:AF166367 xref: EMBL:AF166368 xref: EMBL:AF166369 xref: EMBL:AF166370 xref: EMBL:AF166371 xref: EMBL:AF166372 xref: EMBL:AF166373 xref: EMBL:AF166374 xref: EMBL:AF166375 xref: EMBL:AF167332 xref: EMBL:AL035426 xref: EMBL:AL356213 xref: EMBL:AL590139 xref: EMBL:U10301 xref: EMBL:U10302 xref: EMBL:X82068 xref: EMBL:Z82899 xref: EMBL:Z83848 xref: HGNC:HGNC:4573 xref: UniGene:Hs.377070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020622 ! GRIA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018063 name: GRIA4_human def: "Glutamate receptor 4 precursor gene" [UniProtKB:P48058] synonym: "GLUR4" EXACT [UniProtKB:P48058] xref: EMBL:U16129 xref: HGNC:HGNC:4574 xref: UniGene:Hs.503743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020623 ! GRIA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018064 name: GRID2_human def: "Glutamate receptor delta-2 subunit precursor gene" [UniProtKB:O43424] synonym: "GLURD2" EXACT [UniProtKB:O43424] xref: EMBL:AF009014 xref: HGNC:HGNC:4576 xref: UniGene:Hs.480281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054481 ! GRID2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018065 name: GRIK1_human def: "Glutamate receptor, ionotropic kainate 1 precursor gene" [UniProtKB:P39086] synonym: "GLUR5" EXACT [UniProtKB:P39086] xref: EMBL:AJ249208 xref: EMBL:L19058 xref: EMBL:U16125 xref: HGNC:HGNC:4579 xref: UniGene:Hs.695938 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020614 ! GRIK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018066 name: GRIK2_human def: "Glutamate receptor, ionotropic kainate 2 precursor gene" [UniProtKB:Q13002] synonym: "GLUR6" EXACT [UniProtKB:Q13002] xref: EMBL:AJ252246 xref: EMBL:AJ301608 xref: EMBL:AJ301609 xref: EMBL:AJ301610 xref: EMBL:U16126 xref: HGNC:HGNC:4580 xref: UniGene:Hs.654523 xref: UniGene:Hs.98262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020611 ! GRIK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018067 name: GRIK3_human def: "Glutamate receptor, ionotropic kainate 3 precursor gene" [UniProtKB:Q13003] synonym: "GLUR7" EXACT [UniProtKB:Q13003] xref: EMBL:AC117945 xref: EMBL:AL355386 xref: EMBL:CH471059 xref: EMBL:S69349 xref: EMBL:U16127 xref: EMBL:U16128 xref: HGNC:HGNC:4581 xref: UniGene:Hs.128848 xref: UniGene:Hs.654524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020605 ! GRIK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018068 name: GRIK4_human def: "Glutamate receptor, ionotropic kainate 4 precursor gene" [UniProtKB:Q16099] synonym: "GRIK" EXACT [UniProtKB:Q16099] xref: EMBL:AK292726 xref: EMBL:CH471065 xref: EMBL:S67803 xref: HGNC:HGNC:4582 xref: UniGene:Hs.568901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020617 ! GRIK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018069 name: GRIP1_human def: "Glutamate receptor-interacting protein 1 gene" [UniProtKB:Q9Y3R0] xref: EMBL:AC090710 xref: EMBL:AC122686 xref: EMBL:AC135251 xref: EMBL:AJ133439 xref: HGNC:HGNC:18708 xref: UniGene:Hs.505946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059343 ! GRIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018070 name: GARNL1_human def: "GTPase-activating Rap/Ran-GAP domain-like 1 gene" [UniProtKB:Q6GYQ0] synonym: "KIAA0884" EXACT [UniProtKB:Q6GYQ0] synonym: "TULIP1" EXACT [UniProtKB:Q6GYQ0] xref: EMBL:AB020691 xref: EMBL:AK126975 xref: EMBL:AL160231 xref: EMBL:AL834362 xref: EMBL:AY596970 xref: EMBL:AY596971 xref: EMBL:BC042013 xref: EMBL:BC042045 xref: HGNC:HGNC:17770 xref: UniGene:Hs.113150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056736 ! GRIPE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018071 name: GRK4_human def: "G protein-coupled receptor kinase 4 gene" [UniProtKB:P32298] synonym: "GPRK2L" EXACT [UniProtKB:P32298] synonym: "GPRK4" EXACT [UniProtKB:P32298] xref: EMBL:BC117320 xref: EMBL:L03718 xref: EMBL:U33054 xref: EMBL:U33055 xref: EMBL:U33056 xref: EMBL:U33153 xref: EMBL:U33154 xref: EMBL:U33155 xref: EMBL:U33156 xref: EMBL:U33157 xref: EMBL:U33158 xref: EMBL:U33159 xref: EMBL:U33160 xref: EMBL:U33161 xref: EMBL:U33162 xref: EMBL:U33163 xref: EMBL:U33164 xref: EMBL:U33165 xref: EMBL:U33166 xref: EMBL:U33167 xref: EMBL:U33168 xref: EMBL:X75897 xref: EMBL:X97879 xref: EMBL:X97880 xref: EMBL:X97881 xref: EMBL:X98118 xref: EMBL:Z68192 xref: HGNC:HGNC:4543 xref: UniGene:Hs.32959 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055259 ! GRK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018072 name: GRK5_human def: "G protein-coupled receptor kinase 5 gene" [UniProtKB:P34947] synonym: "GPRK5" EXACT [UniProtKB:P34947] xref: EMBL:AL355273 xref: EMBL:AL355861 xref: EMBL:AL583824 xref: EMBL:BC064506 xref: EMBL:CH471066 xref: EMBL:L15388 xref: HGNC:HGNC:4544 xref: UniGene:Hs.524625 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055271 ! GRK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018073 name: GRK6_human def: "G protein-coupled receptor kinase 6 gene" [UniProtKB:P43250] synonym: "GPRK6" EXACT [UniProtKB:P43250] xref: EMBL:AF040751 xref: EMBL:AF040752 xref: EMBL:BC009277 xref: EMBL:L16862 xref: EMBL:U00686 xref: HGNC:HGNC:4545 xref: UniGene:Hs.235116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055361 ! GRK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018074 name: GRK7_human def: "G protein-coupled receptor kinase 7 precursor gene" [UniProtKB:Q8WTQ7] synonym: "GPRK7" EXACT [UniProtKB:Q8WTQ7] xref: EMBL:AF282269 xref: EMBL:AF439409 xref: HGNC:HGNC:17031 xref: UniGene:Hs.680654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057968 ! GRK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018075 name: RASGRP1_human def: "RAS guanyl-releasing protein 1 gene" [UniProtKB:O95267] synonym: "RASGRP" EXACT [UniProtKB:O95267] xref: EMBL:AB208848 xref: EMBL:AF081195 xref: EMBL:AF081197 xref: EMBL:AF106071 xref: EMBL:AY634315 xref: EMBL:AY858556 xref: EMBL:AY954625 xref: EMBL:AY966005 xref: EMBL:BC067298 xref: EMBL:BC109296 xref: EMBL:BC109297 xref: HGNC:HGNC:9878 xref: UniGene:Hs.591127 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054743 ! GRP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018076 name: RASGRP2_human def: "RAS guanyl-releasing protein 2 gene" [UniProtKB:Q7LDG7] synonym: "CDC25L" EXACT [UniProtKB:Q7LDG7] synonym: "MCG7" EXACT [UniProtKB:Q7LDG7] xref: EMBL:AF043722 xref: EMBL:AF043723 xref: EMBL:AF081194 xref: EMBL:AP001462 xref: EMBL:BC117151 xref: EMBL:CH471076 xref: EMBL:U78170 xref: EMBL:Y12336 xref: HGNC:HGNC:9879 xref: UniGene:Hs.99491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053846 ! A6NHE2_HUMAN relationship: codes_for CCO:B0053867 ! A6NJ28_HUMAN relationship: codes_for CCO:B0057123 ! GRP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018077 name: RASGRP3_human def: "Ras guanyl-releasing protein 3 gene" [UniProtKB:Q8IV61] synonym: "GRP3" EXACT [UniProtKB:Q8IV61] synonym: "KIAA0846" EXACT [UniProtKB:Q8IV61] xref: EMBL:AB020653 xref: EMBL:BC027849 xref: HGNC:HGNC:14545 xref: UniGene:Hs.143674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057337 ! GRP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018078 name: RASGRP4_human def: "RAS guanyl-releasing protein 4 gene" [UniProtKB:Q8TDF6] xref: EMBL:AF448437 xref: EMBL:AK097292 xref: EMBL:AY048119 xref: EMBL:AY048120 xref: EMBL:AY048121 xref: EMBL:BC146669 xref: EMBL:BC150202 xref: HGNC:HGNC:18958 xref: UniGene:Hs.130434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057927 ! GRP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018079 name: GRPR_human def: "Gastrin-releasing peptide receptor gene" [UniProtKB:P30550] xref: EMBL:AF293321 xref: EMBL:AF293322 xref: EMBL:AF293323 xref: EMBL:BC074733 xref: EMBL:M73481 xref: HGNC:HGNC:4609 xref: UniGene:Hs.567282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055222 ! GRPR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018080 name: GRP_human def: "Gastrin-releasing peptide precursor gene" [UniProtKB:P07492] xref: EMBL:BC004488 xref: EMBL:BT006803 xref: EMBL:CH471096 xref: EMBL:K02054 xref: EMBL:M12511 xref: EMBL:M12512 xref: EMBL:M12550 xref: HGNC:HGNC:4605 xref: UniGene:Hs.153444 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054913 ! GRP_HUMAN relationship: codes_for CCO:B0056368 ! Q53YA0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018081 name: GRTP1_human def: "Growth hormone-regulated TBC protein 1 gene" [UniProtKB:Q5TC63] synonym: "TBC1D6" EXACT [UniProtKB:Q5TC63] xref: EMBL:AK026127 xref: EMBL:AL136221 xref: EMBL:BC033071 xref: EMBL:BC062461 xref: EMBL:BC080640 xref: EMBL:BC112123 xref: EMBL:BC112125 xref: HGNC:HGNC:20310 xref: UniGene:Hs.170904 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056609 ! GRTP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018082 name: GSC2_human def: "Homeobox protein goosecoid-2 gene" [UniProtKB:O15499] synonym: "GSCL" EXACT [UniProtKB:O15499] xref: EMBL:U96402 xref: HGNC:HGNC:4613 xref: UniGene:Hs.534318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054439 ! GSC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018083 name: GSC_human def: "Homeobox protein goosecoid gene" [UniProtKB:P56915] xref: EMBL:AY177407 xref: EMBL:BC063580 xref: HGNC:HGNC:4612 xref: UniGene:Hs.440438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055553 ! GSC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018084 name: GCLM_human def: "Glutamate--cysteine ligase regulatory subunit gene" [UniProtKB:P48507] synonym: "GLCLR" EXACT [UniProtKB:P48507] xref: EMBL:AL049796 xref: EMBL:AL117351 xref: EMBL:AY773965 xref: EMBL:BC041809 xref: EMBL:CR541833 xref: EMBL:L35546 xref: HGNC:HGNC:4312 xref: UniGene:Hs.315562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055405 ! GSH0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018085 name: GCLC_human def: "Glutamate--cysteine ligase catalytic subunit gene" [UniProtKB:P48506] synonym: "GLCL" EXACT [UniProtKB:P48506] synonym: "GLCLC" EXACT [UniProtKB:P48506] xref: EMBL:AF118846 xref: EMBL:AL033397 xref: EMBL:AY780794 xref: EMBL:BC022487 xref: EMBL:BC039894 xref: EMBL:L39773 xref: EMBL:M90656 xref: HGNC:HGNC:4311 xref: UniGene:Hs.654465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055404 ! GSH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018086 name: GSBS_human def: "G-substrate gene" [UniProtKB:O96001] synonym: "C7orf16" EXACT [UniProtKB:O96001] xref: EMBL:AC006325 xref: EMBL:AF071789 xref: EMBL:AF097730 xref: EMBL:BC028094 xref: HGNC:HGNC:16973 xref: UniGene:Hs.227011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054818 ! GSUB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018087 name: GTF2IRD1_human def: "General transcription factor II-I repeat domain-containing protein 1 gene" [UniProtKB:Q9UHL9] synonym: "CREAM1" EXACT [UniProtKB:Q9UHL9] synonym: "GTF3" EXACT [UniProtKB:Q9UHL9] synonym: "MUSTRD1" EXACT [UniProtKB:Q9UHL9] synonym: "RBAP2" EXACT [UniProtKB:Q9UHL9] synonym: "WBSCR11" EXACT [UniProtKB:Q9UHL9] synonym: "WBSCR12" EXACT [UniProtKB:Q9UHL9] xref: EMBL:AC004851 xref: EMBL:AC005231 xref: EMBL:AF089107 xref: EMBL:AF104923 xref: EMBL:AF118270 xref: EMBL:AF151354 xref: EMBL:AF156489 xref: EMBL:BC018136 xref: HGNC:HGNC:4661 xref: UniGene:Hs.647056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027079 ! GT2D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018088 name: GTF2IRD2_human def: "General transcription factor II-I repeat domain-containing protein 2A gene" [UniProtKB:Q86UP8] synonym: "GTF2IRD2A" EXACT [UniProtKB:Q86UP8] xref: EMBL:AK291431 xref: EMBL:AL833932 xref: EMBL:AL834153 xref: EMBL:AY260739 xref: EMBL:AY312853 xref: EMBL:AY312854 xref: EMBL:AY336979 xref: EMBL:AY336980 xref: EMBL:AY336981 xref: EMBL:BC047706 xref: EMBL:BC061590 xref: EMBL:BC067859 xref: HGNC:HGNC:30775 xref: UniGene:Hs.647017 xref: UniGene:Hs.647027 xref: UniGene:Hs.647039 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057250 ! GTD2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018089 name: GTF2IRD2B_human def: "General transcription factor II-I repeat domain-containing protein 2B gene" [UniProtKB:Q6EKJ0] xref: EMBL:AK025076 xref: EMBL:AK095572 xref: EMBL:AY312850 xref: EMBL:AY312851 xref: HGNC:HGNC:33125 xref: UniGene:Hs.647017 xref: UniGene:Hs.647027 xref: UniGene:Hs.647039 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056732 ! GTD2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018090 name: GTF2I_human def: "General transcription factor II-I gene" [UniProtKB:P78347] synonym: "BAP135" EXACT [UniProtKB:P78347] synonym: "WBSCR6" EXACT [UniProtKB:P78347] xref: EMBL:AC004883 xref: EMBL:AF015553 xref: EMBL:AF035737 xref: EMBL:AF038967 xref: EMBL:AF038968 xref: EMBL:AF038969 xref: EMBL:BC004472 xref: EMBL:BC070484 xref: EMBL:U77948 xref: EMBL:Y14946 xref: HGNC:HGNC:4659 xref: UniGene:Hs.647041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027081 ! GTF2I_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018091 name: GUCA1A_human def: "Guanylyl cyclase-activating protein 1 gene" [UniProtKB:P43080] synonym: "GCAP" EXACT [UniProtKB:P43080] synonym: "GCAP1" EXACT [UniProtKB:P43080] synonym: "GUCA1" EXACT [UniProtKB:P43080] xref: EMBL:AL096814 xref: EMBL:BC031663 xref: EMBL:L36859 xref: EMBL:L36861 xref: HGNC:HGNC:4678 xref: UniGene:Hs.92858 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055357 ! GUC1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018092 name: GUCA1C_human def: "Guanylyl cyclase-activating protein 3 gene" [UniProtKB:O95843] synonym: "GCAP3" EXACT [UniProtKB:O95843] xref: EMBL:AF109998 xref: EMBL:AF109999 xref: EMBL:AF110000 xref: EMBL:AF110001 xref: EMBL:AF110002 xref: EMBL:AF110003 xref: HGNC:HGNC:4680 xref: UniGene:Hs.233363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054800 ! GUC1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018093 name: GUCA2A_human def: "Guanylin precursor gene" [UniProtKB:Q02747] synonym: "GUCA2" EXACT [UniProtKB:Q02747] xref: EMBL:M95174 xref: EMBL:M97496 xref: EMBL:X74322 xref: HGNC:HGNC:4682 xref: UniGene:Hs.778 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055714 ! GUC2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018094 name: GUF1_human def: "GTP-binding protein GUF1 homolog gene" [UniProtKB:Q8N442] xref: EMBL:AK023282 xref: EMBL:AK025248 xref: EMBL:BC036768 xref: HGNC:HGNC:25799 xref: UniGene:Hs.546419 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057463 ! GUF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018095 name: GZF1_human def: "GDNF-inducible zinc finger protein 1 gene" [UniProtKB:Q9H116] synonym: "ZBTB23" EXACT [UniProtKB:Q9H116] synonym: "ZNF336" EXACT [UniProtKB:Q9H116] xref: EMBL:AB100265 xref: EMBL:AK025447 xref: EMBL:AK056159 xref: EMBL:AL096677 xref: HGNC:HGNC:15808 xref: UniGene:Hs.699339 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058659 ! GZF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018096 name: H1FNT_human def: "Testis-specific H1 histone gene" [UniProtKB:Q75WM6] synonym: "HANP1" EXACT [UniProtKB:Q75WM6] xref: EMBL:AB121028 xref: EMBL:AC024257 xref: EMBL:AY302593 xref: EMBL:AY496854 xref: EMBL:BC118635 xref: EMBL:BC119787 xref: HGNC:HGNC:24893 xref: UniGene:Hs.155833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043830 ! H1FNT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018097 name: H1FOO_human def: "Histone H1oo gene" [UniProtKB:Q8IZA3] synonym: "H1OO" EXACT [UniProtKB:Q8IZA3] synonym: "OSH1" EXACT [UniProtKB:Q8IZA3] xref: EMBL:AY158091 xref: EMBL:BC047943 xref: EMBL:CH471052 xref: HGNC:HGNC:18463 xref: UniGene:Hs.97358 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0043831 ! H1FOO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018098 name: H2AFY2_human def: "Core histone macro-H2A.2 gene" [UniProtKB:Q9P0M6] synonym: "MACROH2A2" EXACT [UniProtKB:Q9P0M6] xref: EMBL:AF151534 xref: EMBL:AF336304 xref: EMBL:AK022776 xref: EMBL:AL731540 xref: EMBL:BC016172 xref: HGNC:HGNC:14453 xref: UniGene:Hs.499953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059032 ! H2AW_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018099 name: H2AFY_human def: "Core histone macro-H2A.1 gene" [UniProtKB:O75367] synonym: "MACROH2A1" EXACT [UniProtKB:O75367] xref: EMBL:AF041483 xref: EMBL:AF044286 xref: EMBL:AF054174 xref: EMBL:AK023409 xref: EMBL:AY134746 xref: EMBL:BC013331 xref: EMBL:BC095406 xref: HGNC:HGNC:4740 xref: UniGene:Hs.599225 xref: UniGene:Hs.696013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054625 ! H2AY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018100 name: HIST2H3D_human def: "Histone H3.2 gene" [UniProtKB:Q71DI3] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0005285 ! H32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018101 name: HR_human def: "Protein hairless gene" [UniProtKB:O43593] xref: EMBL:AF039196 xref: EMBL:AJ277165 xref: EMBL:AJ277249 xref: EMBL:AJ277250 xref: EMBL:AJ277251 xref: EMBL:AJ277252 xref: EMBL:AJ277253 xref: EMBL:AJ400825 xref: EMBL:AJ400826 xref: EMBL:AJ400827 xref: EMBL:AJ400828 xref: EMBL:AJ400829 xref: EMBL:AJ400830 xref: EMBL:AJ400831 xref: EMBL:AJ400832 xref: EMBL:AJ400833 xref: EMBL:AJ400834 xref: EMBL:AJ400835 xref: EMBL:AJ400836 xref: EMBL:AJ400837 xref: EMBL:BC067128 xref: HGNC:HGNC:5172 xref: UniGene:Hs.272367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054495 ! HAIR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018102 name: HAND1_human def: "Heart- and neural crest derivatives-expressed protein 1 gene" [UniProtKB:O96004] synonym: "EHAND" EXACT [UniProtKB:O96004] xref: EMBL:AF061756 xref: EMBL:AF063012 xref: EMBL:BC021190 xref: HGNC:HGNC:4807 xref: UniGene:Hs.152531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054819 ! HAND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018103 name: HAND2_human def: "Heart- and neural crest derivatives-expressed protein 2 gene" [UniProtKB:P61296] synonym: "DHAND" EXACT [UniProtKB:P61296] xref: EMBL:AF087940 xref: EMBL:AF087941 xref: EMBL:BC101406 xref: HGNC:HGNC:4808 xref: UniGene:Hs.388245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055608 ! HAND2_HUMAN relationship: codes_for CCO:B0056289 ! Q494T1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018104 name: PDAP1_human def: "28 kDa heat- and acid-stable phosphoprotein gene" [UniProtKB:Q13442] synonym: "HASPP28" EXACT [UniProtKB:Q13442] xref: EMBL:AC004922 xref: EMBL:BC000684 xref: EMBL:BC007873 xref: EMBL:U41745 xref: EMBL:U65960 xref: HGNC:HGNC:14634 xref: UniGene:Hs.632296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055908 ! HAP28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018105 name: HBB_human def: "Hemoglobin subunit beta gene" [UniProtKB:P68871] xref: EMBL:A01592 xref: EMBL:AF007546 xref: EMBL:AF117710 xref: EMBL:AF181989 xref: EMBL:AF349114 xref: EMBL:AF527577 xref: EMBL:AY136510 xref: EMBL:AY163866 xref: EMBL:AY260740 xref: EMBL:BC007075 xref: EMBL:CR536530 xref: EMBL:CR541913 xref: EMBL:DQ126270 xref: EMBL:DQ126271 xref: EMBL:DQ126272 xref: EMBL:DQ126273 xref: EMBL:DQ126274 xref: EMBL:DQ126275 xref: EMBL:DQ126276 xref: EMBL:DQ126277 xref: EMBL:DQ126278 xref: EMBL:DQ126279 xref: EMBL:DQ126280 xref: EMBL:DQ126281 xref: EMBL:DQ126282 xref: EMBL:DQ126283 xref: EMBL:DQ126284 xref: EMBL:DQ126285 xref: EMBL:DQ126286 xref: EMBL:DQ126287 xref: EMBL:DQ126288 xref: EMBL:DQ126289 xref: EMBL:DQ126290 xref: EMBL:DQ126291 xref: EMBL:DQ126292 xref: EMBL:DQ126293 xref: EMBL:DQ126294 xref: EMBL:DQ126295 xref: EMBL:DQ126296 xref: EMBL:DQ126297 xref: EMBL:DQ126298 xref: EMBL:DQ126299 xref: EMBL:DQ126300 xref: EMBL:DQ126301 xref: EMBL:DQ126302 xref: EMBL:DQ126303 xref: EMBL:DQ126304 xref: EMBL:DQ126305 xref: EMBL:DQ126306 xref: EMBL:DQ126307 xref: EMBL:DQ126308 xref: EMBL:DQ126309 xref: EMBL:DQ126310 xref: EMBL:DQ126311 xref: EMBL:DQ126312 xref: EMBL:DQ126313 xref: EMBL:DQ126314 xref: EMBL:DQ126315 xref: EMBL:DQ126316 xref: EMBL:DQ126317 xref: EMBL:DQ126318 xref: EMBL:DQ126319 xref: EMBL:DQ126320 xref: EMBL:DQ126321 xref: EMBL:DQ126322 xref: EMBL:DQ126323 xref: EMBL:DQ126324 xref: EMBL:DQ126325 xref: EMBL:L26462 xref: EMBL:L26463 xref: EMBL:L26464 xref: EMBL:L26465 xref: EMBL:L26466 xref: EMBL:L26467 xref: EMBL:L26468 xref: EMBL:L26469 xref: EMBL:L26470 xref: EMBL:L26471 xref: EMBL:L26472 xref: EMBL:L26473 xref: EMBL:L26474 xref: EMBL:L26475 xref: EMBL:L26476 xref: EMBL:L26477 xref: EMBL:L26478 xref: EMBL:L48213 xref: EMBL:L48214 xref: EMBL:L48215 xref: EMBL:L48216 xref: EMBL:L48217 xref: EMBL:L48932 xref: EMBL:M11428 xref: EMBL:M25079 xref: EMBL:M25113 xref: EMBL:M36640 xref: EMBL:U01317 xref: EMBL:V00497 xref: EMBL:V00499 xref: EMBL:V00500 xref: HGNC:HGNC:4827 xref: UniGene:Hs.523443 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055635 ! HBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018106 name: HBS1L_human def: "HBS1-like protein gene" [UniProtKB:Q9Y450] synonym: "HBS1" EXACT [UniProtKB:Q9Y450] synonym: "KIAA1038" EXACT [UniProtKB:Q9Y450] xref: EMBL:AB028961 xref: EMBL:AJ459826 xref: EMBL:AJ459827 xref: EMBL:AL353596 xref: EMBL:AL445190 xref: EMBL:BC001465 xref: EMBL:BC040849 xref: EMBL:U87791 xref: HGNC:HGNC:4834 xref: UniGene:Hs.378532 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059347 ! HBS1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018107 name: HCC1_human def: "Nuclear protein Hcc-1 gene" [UniProtKB:P82979] synonym: "HSPC316" EXACT [UniProtKB:P82979] xref: EMBL:AF161434 xref: EMBL:AF486281 xref: EMBL:AJ409089 xref: EMBL:BC007099 xref: UniGene:Hs.505676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055658 ! HCC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018108 name: HCLS1_human def: "Hematopoietic lineage cell-specific protein gene" [UniProtKB:P14317] synonym: "HS1" EXACT [UniProtKB:P14317] xref: EMBL:BC016758 xref: EMBL:X16663 xref: HGNC:HGNC:4844 xref: UniGene:Hs.14601 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055023 ! HCLS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018109 name: HDAC8_human def: "Histone deacetylase 8 gene" [UniProtKB:Q9BY41] synonym: "CDA07" EXACT [UniProtKB:Q9BY41] synonym: "HDACL1" EXACT [UniProtKB:Q9BY41] xref: EMBL:AA376331 xref: EMBL:AF212246 xref: EMBL:AF230097 xref: EMBL:AF245664 xref: EMBL:AI159768 xref: EMBL:AJ277724 xref: EMBL:BX295542 xref: EMBL:T99283 xref: HGNC:HGNC:13315 xref: UniGene:Hs.310536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058569 ! HDAC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018110 name: HDGF_human def: "Hepatoma-derived growth factor gene" [UniProtKB:P51858] synonym: "HMG1L2" EXACT [UniProtKB:P51858] xref: EMBL:AL590666 xref: EMBL:BC018991 xref: EMBL:D16431 xref: HGNC:HGNC:4856 xref: UniGene:Hs.506748 xref: UniGene:Hs.597384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055484 ! HDGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018111 name: HDGFRP3_human def: "Hepatoma-derived growth factor-related protein 3 gene" [UniProtKB:Q9Y3E1] synonym: "CGI-142" EXACT [UniProtKB:Q9Y3E1] synonym: "HDGF2" EXACT [UniProtKB:Q9Y3E1] xref: EMBL:AB029156 xref: EMBL:AF110642 xref: EMBL:AF151900 xref: EMBL:AK001280 xref: EMBL:BC015483 xref: EMBL:BC040554 xref: UniGene:Hs.513954 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059336 ! HDGR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018112 name: HDX_human def: "Highly divergent homeobox gene" [UniProtKB:Q7Z353] synonym: "CXorf43" EXACT [UniProtKB:Q7Z353] xref: EMBL:AK055240 xref: EMBL:AL022160 xref: EMBL:AL035552 xref: EMBL:BC101720 xref: EMBL:BC101722 xref: EMBL:BX538112 xref: EMBL:CH471104 xref: HGNC:HGNC:26411 xref: UniGene:Hs.559546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057145 ! HDX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018113 name: HELB_human def: "DNA helicase B gene" [UniProtKB:Q8NG08] xref: EMBL:AF319995 xref: EMBL:AK024464 xref: EMBL:AK290894 xref: EMBL:BC037946 xref: HGNC:HGNC:17196 xref: UniGene:Hs.505941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057611 ! HELB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018114 name: HEMK1_human def: "HemK methyltransferase family member 1 gene" [UniProtKB:Q9Y5R4] synonym: "HEMK" EXACT [UniProtKB:Q9Y5R4] xref: EMBL:AF131220 xref: EMBL:AF172244 xref: EMBL:BC000781 xref: HGNC:HGNC:24923 xref: UniGene:Hs.517987 xref: UniGene:Hs.705830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059382 ! HEMK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018115 name: NHLH1_human def: "Helix-loop-helix protein 1 gene" [UniProtKB:Q02575] synonym: "HEN1" EXACT [UniProtKB:Q02575] xref: EMBL:BC013789 xref: EMBL:M97507 xref: HGNC:HGNC:7817 xref: UniGene:Hs.30956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055711 ! HEN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018116 name: NHLH2_human def: "Helix-loop-helix protein 2 gene" [UniProtKB:Q02577] synonym: "HEN2" EXACT [UniProtKB:Q02577] synonym: "KIAA0490" EXACT [UniProtKB:Q02577] xref: EMBL:AB007959 xref: EMBL:AL449264 xref: EMBL:BC096359 xref: EMBL:BC096360 xref: EMBL:M97508 xref: HGNC:HGNC:7818 xref: UniGene:Hs.46296 xref: UniGene:Hs.657159 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053936 ! A6PVY9_HUMAN relationship: codes_for CCO:B0055712 ! HEN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018117 name: HES1_human def: "Transcription factor HES-1 gene" [UniProtKB:Q14469] synonym: "HL" EXACT [UniProtKB:Q14469] synonym: "HRY" EXACT [UniProtKB:Q14469] xref: EMBL:AF264785 xref: EMBL:AK000415 xref: EMBL:L19314 xref: HGNC:HGNC:5192 xref: UniGene:Hs.250666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055986 ! HES1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018118 name: HES2_human def: "Transcription factor HES-2 gene" [UniProtKB:Q9Y543] xref: EMBL:AL031848 xref: EMBL:BC012091 xref: HGNC:HGNC:16005 xref: UniGene:Hs.118727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059368 ! HES2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018119 name: HES3_human def: "Transcription factor HES-3 gene" [UniProtKB:Q5TGS1] xref: EMBL:AL031847 xref: HGNC:HGNC:26226 xref: UniGene:Hs.532677 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056625 ! HES3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018120 name: HES4_human def: "Transcription factor HES-4 gene" [UniProtKB:Q9HCC6] xref: EMBL:AB048791 xref: EMBL:AL645608 xref: EMBL:BC012351 xref: HGNC:HGNC:24149 xref: UniGene:Hs.154029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058801 ! HES4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018121 name: HES5_human def: "Transcription factor HES-5 gene" [UniProtKB:Q5TA89] xref: EMBL:AL139246 xref: EMBL:BC087840 xref: EMBL:DQ272660 xref: HGNC:HGNC:19764 xref: UniGene:Hs.57971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056522 ! Q5M8T3_HUMAN relationship: codes_for CCO:B0056603 ! HES5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018122 name: HES6_human def: "Transcription cofactor HES-6 gene" [UniProtKB:Q96HZ4] xref: EMBL:AB035179 xref: EMBL:AC016757 xref: EMBL:AF260237 xref: EMBL:AK075040 xref: EMBL:BC007939 xref: HGNC:HGNC:18254 xref: UniGene:Hs.42949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058223 ! HES6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018123 name: HES7_human def: "Transcription factor HES-7 gene" [UniProtKB:Q9BYE0] xref: EMBL:AB049064 xref: HGNC:HGNC:15977 xref: UniGene:Hs.434828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058576 ! HES7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018124 name: HESX1_human def: "Homeobox expressed in ES cells 1 gene" [UniProtKB:Q9UBX0] synonym: "HANF" EXACT [UniProtKB:Q9UBX0] xref: EMBL:AF059734 xref: EMBL:BC069515 xref: EMBL:BC093979 xref: EMBL:BC112089 xref: EMBL:U65437 xref: EMBL:U82811 xref: HGNC:HGNC:4877 xref: UniGene:Hs.171980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059089 ! HESX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018125 name: HEXB_human def: "Beta-hexosaminidase subunit beta precursor gene" [UniProtKB:P07686] synonym: "HCC7" EXACT [UniProtKB:P07686] xref: EMBL:AF378118 xref: EMBL:BC017378 xref: EMBL:BT009919 xref: EMBL:M13519 xref: EMBL:M19735 xref: EMBL:M23282 xref: EMBL:M23283 xref: EMBL:M23284 xref: EMBL:M23285 xref: EMBL:M23286 xref: EMBL:M23287 xref: EMBL:M23288 xref: EMBL:M23290 xref: EMBL:M23291 xref: EMBL:M23292 xref: EMBL:M23293 xref: EMBL:M23294 xref: EMBL:M34906 xref: HGNC:HGNC:4879 xref: UniGene:Hs.69293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054915 ! HEXB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018126 name: HEY1_human def: "Hairy/enhancer-of-split related with YRPW motif protein 1 gene" [UniProtKB:Q9Y5J3] synonym: "CHF2" EXACT [UniProtKB:Q9Y5J3] synonym: "HERP2" EXACT [UniProtKB:Q9Y5J3] synonym: "HESR1" EXACT [UniProtKB:Q9Y5J3] synonym: "HRT1" EXACT [UniProtKB:Q9Y5J3] xref: EMBL:AF151522 xref: EMBL:AF176422 xref: EMBL:AF232239 xref: EMBL:AF311883 xref: EMBL:AJ272214 xref: EMBL:BC001873 xref: EMBL:BT020065 xref: HGNC:HGNC:4880 xref: UniGene:Hs.234434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059378 ! HEY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018127 name: HEY2_human def: "Hairy/enhancer-of-split related with YRPW motif protein 2 gene" [UniProtKB:Q9UBP5] synonym: "CHF1" EXACT [UniProtKB:Q9UBP5] synonym: "GRL" EXACT [UniProtKB:Q9UBP5] synonym: "HERP" EXACT [UniProtKB:Q9UBP5] synonym: "HERP1" EXACT [UniProtKB:Q9UBP5] synonym: "HRT2" EXACT [UniProtKB:Q9UBP5] xref: EMBL:AB044755 xref: EMBL:AF173901 xref: EMBL:AF232238 xref: EMBL:AF237949 xref: EMBL:AF311884 xref: EMBL:AJ249545 xref: EMBL:AL078594 xref: EMBL:BC007707 xref: EMBL:BT020067 xref: EMBL:BT020068 xref: HGNC:HGNC:4881 xref: UniGene:Hs.144287 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056618 ! Q5TF93_HUMAN relationship: codes_for CCO:B0059081 ! HEY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018128 name: HEYL_human def: "Hairy/enhancer-of-split related with YRPW motif-like protein gene" [UniProtKB:Q9NQ87] synonym: "HRT3" EXACT [UniProtKB:Q9NQ87] xref: EMBL:AF311885 xref: EMBL:AJ272215 xref: EMBL:AL035404 xref: EMBL:BC006087 xref: HGNC:HGNC:4882 xref: UniGene:Hs.472566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058865 ! HEYL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018129 name: HHATL_human def: "Protein-cysteine N-palmitoyltransferase HHAT-like protein gene" [UniProtKB:Q9HCP6] synonym: "C3orf3" EXACT [UniProtKB:Q9HCP6] synonym: "GUP1" EXACT [UniProtKB:Q9HCP6] synonym: "KIAA1173" EXACT [UniProtKB:Q9HCP6] xref: EMBL:AB032999 xref: EMBL:AB042554 xref: EMBL:BC022529 xref: HGNC:HGNC:13242 xref: UniGene:Hs.476041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058815 ! HHATL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018130 name: HHIP_human def: "Hedgehog-interacting protein precursor gene" [UniProtKB:Q96QV1] synonym: "HIP" EXACT [UniProtKB:Q96QV1] synonym: "UNQ5825/PRO19644" EXACT [UniProtKB:Q96QV1] xref: EMBL:AF326459 xref: EMBL:AF326460 xref: EMBL:AF326461 xref: EMBL:AF326462 xref: EMBL:AF326463 xref: EMBL:AF326464 xref: EMBL:AF326465 xref: EMBL:AF326466 xref: EMBL:AF326467 xref: EMBL:AF326468 xref: EMBL:AF326469 xref: EMBL:AF326470 xref: EMBL:AF326471 xref: EMBL:AK024645 xref: EMBL:AK074711 xref: EMBL:AY009317 xref: EMBL:AY009951 xref: EMBL:AY358747 xref: EMBL:BC009298 xref: EMBL:BC025311 xref: HGNC:HGNC:14866 xref: UniGene:Hs.507991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015164 ! HHIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018131 name: HIF1AN_human def: "Hypoxia-inducible factor 1-alpha inhibitor gene" [UniProtKB:Q9NWT6] synonym: "FIH1" EXACT [UniProtKB:Q9NWT6] xref: EMBL:AF395830 xref: EMBL:AK000622 xref: EMBL:AL133352 xref: EMBL:AL359615 xref: EMBL:BC007719 xref: HGNC:HGNC:17113 xref: UniGene:Hs.500788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058941 ! HIF1N_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018132 name: HINT1_human def: "Histidine triad nucleotide-binding protein 1 gene" [UniProtKB:P49773] synonym: "HINT" EXACT [UniProtKB:P49773] synonym: "PKCI1" EXACT [UniProtKB:P49773] synonym: "PRKCNH1" EXACT [UniProtKB:P49773] xref: EMBL:AK026557 xref: EMBL:BC001287 xref: EMBL:BC007090 xref: EMBL:CR457048 xref: EMBL:U27143 xref: EMBL:U51004 xref: HGNC:HGNC:4912 xref: UniGene:Hs.483305 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055436 ! HINT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018133 name: HIPK3_human def: "Homeodomain-interacting protein kinase 3 gene" [UniProtKB:Q9H422] synonym: "DYRK6" EXACT [UniProtKB:Q9H422] synonym: "FIST3" EXACT [UniProtKB:Q9H422] synonym: "PKY" EXACT [UniProtKB:Q9H422] xref: EMBL:AF004849 xref: EMBL:AF305239 xref: EMBL:AL122015 xref: EMBL:Y09306 xref: HGNC:HGNC:4915 xref: UniGene:Hs.201918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015655 ! HIPK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018134 name: HKR1_human def: "Krueppel-related zinc finger protein 1 gene" [UniProtKB:P10072] xref: EMBL:AB013897 xref: EMBL:AC016590 xref: EMBL:BC004513 xref: EMBL:BC017256 xref: EMBL:CH471126 xref: EMBL:M20675 xref: HGNC:HGNC:4928 xref: UniGene:Hs.657027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054966 ! HKR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018135 name: HLF_human def: "Hepatic leukemia factor gene" [UniProtKB:Q16534] xref: EMBL:BC036093 xref: EMBL:M95585 xref: EMBL:M95586 xref: EMBL:X68985 xref: HGNC:HGNC:4977 xref: UniGene:Hs.196952 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056145 ! HLF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018136 name: HLTF_human def: "Helicase-like transcription factor gene" [UniProtKB:Q14527] synonym: "HIP116A" EXACT [UniProtKB:Q14527] synonym: "RNF80" EXACT [UniProtKB:Q14527] synonym: "SMARCA3" EXACT [UniProtKB:Q14527] synonym: "SNF2L3" EXACT [UniProtKB:Q14527] synonym: "ZBU1" EXACT [UniProtKB:Q14527] xref: EMBL:AJ418064 xref: EMBL:BC044659 xref: EMBL:L34673 xref: EMBL:S64671 xref: EMBL:Z46606 xref: HGNC:HGNC:11099 xref: UniGene:Hs.3068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055989 ! HLTF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018137 name: HLX_human def: "H2.0-like homeobox protein gene" [UniProtKB:Q14774] synonym: "HLX1" EXACT [UniProtKB:Q14774] xref: EMBL:AB208812 xref: EMBL:AF217621 xref: EMBL:AL445423 xref: EMBL:BC007294 xref: EMBL:BC033808 xref: EMBL:CH471100 xref: EMBL:M60721 xref: EMBL:S56767 xref: EMBL:U14325 xref: EMBL:U14326 xref: EMBL:U14327 xref: EMBL:U14328 xref: HGNC:HGNC:4978 xref: UniGene:Hs.645593 xref: UniGene:Hs.74870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056012 ! HLX_HUMAN relationship: codes_for CCO:B0056660 ! Q5VVT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018138 name: HMG2L1_human def: "High mobility group protein 2-like 1 gene" [UniProtKB:Q9UGU5] synonym: "HMGBCG" EXACT [UniProtKB:Q9UGU5] xref: EMBL:AJ010069 xref: EMBL:AJ010070 xref: EMBL:AL008635 xref: EMBL:AL079310 xref: EMBL:CR456504 xref: HGNC:HGNC:5003 xref: UniGene:Hs.588815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059127 ! HM2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018139 name: HMBOX1_human def: "Homeobox-containing protein 1 gene" [UniProtKB:Q6NT76] xref: EMBL:AK025269 xref: EMBL:AY522342 xref: EMBL:BC009259 xref: EMBL:BC069242 xref: EMBL:DQ153248 xref: HGNC:HGNC:26137 xref: UniGene:Hs.591836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056858 ! HMBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018140 name: EN1_human def: "Homeobox protein engrailed-1 gene" [UniProtKB:Q05925] xref: EMBL:AC012665 xref: EMBL:CH471103 xref: EMBL:L12698 xref: EMBL:L12699 xref: HGNC:HGNC:3342 xref: UniGene:Hs.271977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055746 ! HME1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018141 name: EN2_human def: "Homeobox protein engrailed-2 gene" [UniProtKB:P19622] xref: EMBL:AC008060 xref: EMBL:BC104970 xref: EMBL:BC104972 xref: EMBL:J03066 xref: EMBL:L12700 xref: EMBL:L12701 xref: HGNC:HGNC:3343 xref: UniGene:Hs.134989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055109 ! HME2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018142 name: HMGA1_human def: "High mobility group protein HMG-I/HMG-Y gene" [UniProtKB:P17096] synonym: "HMGIY" EXACT [UniProtKB:P17096] xref: EMBL:AF176039 xref: EMBL:BC004924 xref: EMBL:BC008832 xref: EMBL:BC063434 xref: EMBL:BC067083 xref: EMBL:BC071863 xref: EMBL:BC071864 xref: EMBL:L17131 xref: EMBL:M23614 xref: EMBL:M23615 xref: EMBL:M23616 xref: EMBL:M23617 xref: EMBL:M23618 xref: EMBL:M23619 xref: EMBL:X14957 xref: EMBL:X14958 xref: HGNC:HGNC:5010 xref: UniGene:Hs.518805 xref: UniGene:Hs.703764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055082 ! HMGA1_HUMAN relationship: codes_for CCO:B0056820 ! Q6IPL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018143 name: HMGN2_human def: "Non-histone chromosomal protein HMG-17 gene" [UniProtKB:P05204] synonym: "HMG17" EXACT [UniProtKB:P05204] xref: EMBL:AL513365 xref: EMBL:BC000378 xref: EMBL:BC003050 xref: EMBL:BC014644 xref: EMBL:BC032140 xref: EMBL:BC070297 xref: EMBL:BC071707 xref: EMBL:BC072010 xref: EMBL:BC072011 xref: EMBL:BC075837 xref: EMBL:BC081567 xref: EMBL:BC110390 xref: EMBL:CR542122 xref: EMBL:M12623 xref: EMBL:X13546 xref: HGNC:HGNC:4986 xref: UniGene:Hs.181163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054898 ! HMGN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018144 name: HMHA1_human def: "Minor histocompatibility protein HA-1 gene" [UniProtKB:Q92619] synonym: "KIAA0223" EXACT [UniProtKB:Q92619] xref: EMBL:AC004151 xref: EMBL:AF207595 xref: EMBL:AF207596 xref: EMBL:AF207597 xref: EMBL:AF236756 xref: EMBL:AF308045 xref: EMBL:AF308046 xref: EMBL:AF308047 xref: EMBL:AF308048 xref: EMBL:AF308049 xref: EMBL:AF308050 xref: EMBL:AF308051 xref: EMBL:AF308052 xref: EMBL:AF308053 xref: EMBL:AF308054 xref: EMBL:AF308055 xref: EMBL:AF308056 xref: EMBL:AF308057 xref: EMBL:AF308058 xref: EMBL:AF308059 xref: EMBL:AF308060 xref: EMBL:AF308061 xref: EMBL:AF308062 xref: EMBL:AF308063 xref: EMBL:AF308064 xref: EMBL:AF308065 xref: EMBL:AF308066 xref: EMBL:AF311102 xref: EMBL:BC048129 xref: EMBL:BC065223 xref: EMBL:CH471139 xref: EMBL:D86976 xref: HGNC:HGNC:17102 xref: UniGene:Hs.465521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058075 ! HMHA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018145 name: HMOX1_human def: "Heme oxygenase 1 gene" [UniProtKB:P09601] synonym: "HO" EXACT [UniProtKB:P09601] synonym: "HO1" EXACT [UniProtKB:P09601] xref: EMBL:AY460337 xref: EMBL:CR456505 xref: EMBL:M23041 xref: EMBL:X06985 xref: EMBL:X14782 xref: EMBL:Z82244 xref: HGNC:HGNC:5013 xref: UniGene:Hs.517581 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054947 ! HMOX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018146 name: HMX1_human def: "Homeobox protein HMX1 gene" [UniProtKB:Q9NP08] synonym: "H6" EXACT [UniProtKB:Q9NP08] xref: EMBL:M99587 xref: HGNC:HGNC:5017 xref: UniGene:Hs.104134 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058830 ! HMX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018147 name: HMX2_human def: "Homeobox protein HMX2 gene" [UniProtKB:A2RU54] xref: EMBL:BC132758 xref: HGNC:HGNC:5018 xref: UniGene:Hs.444756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053740 ! HMX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018148 name: HMX3_human def: "Homeobox protein HMX3 gene" [UniProtKB:A6NHT5] synonym: "NKX-5.1" EXACT [UniProtKB:A6NHT5] synonym: "NKX5-1" EXACT [UniProtKB:A6NHT5] xref: EMBL:AC012391 xref: EMBL:CH471066 xref: HGNC:HGNC:5019 xref: UniGene:Hs.531194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053851 ! HMX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018149 name: HNF1B_human def: "Hepatocyte nuclear factor 1-beta gene" [UniProtKB:P35680] synonym: "TCF2" EXACT [UniProtKB:P35680] xref: EMBL:BC017714 xref: EMBL:U90279 xref: EMBL:U90280 xref: EMBL:U90281 xref: EMBL:U90282 xref: EMBL:U90283 xref: EMBL:U90284 xref: EMBL:U90285 xref: EMBL:U90286 xref: EMBL:U90287 xref: EMBL:X58840 xref: EMBL:X71348 xref: HGNC:HGNC:11630 xref: UniGene:Hs.191144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055299 ! HNF1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018150 name: HNRPDL_human def: "Heterogeneous nuclear ribonucleoprotein D-like gene" [UniProtKB:O14979] synonym: "JKTBP" EXACT [UniProtKB:O14979] xref: EMBL:AB017018 xref: EMBL:AB017019 xref: EMBL:AB066484 xref: EMBL:AC124016 xref: EMBL:AY453824 xref: EMBL:BC007392 xref: EMBL:BC011714 xref: EMBL:BC071944 xref: EMBL:CR407623 xref: EMBL:D89092 xref: EMBL:D89678 xref: HGNC:HGNC:5037 xref: UniGene:Hs.527105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054395 ! HNRDL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018151 name: HNRNPUL1_human def: "Heterogeneous nuclear ribonucleoprotein U-like protein 1 gene" [UniProtKB:Q9BUJ2] synonym: "E1BAP5" EXACT [UniProtKB:Q9BUJ2] synonym: "HNRPUL1" EXACT [UniProtKB:Q9BUJ2] xref: EMBL:AJ007509 xref: EMBL:AK021455 xref: EMBL:AK127057 xref: EMBL:AL050146 xref: EMBL:BC002564 xref: EMBL:BC009988 xref: EMBL:BC014232 xref: EMBL:BC027713 xref: HGNC:HGNC:17011 xref: UniGene:Hs.699274 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058522 ! HNRL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018152 name: HOMER1_human def: "Homer protein homolog 1 gene" [UniProtKB:Q86YM7] synonym: "SYN47" EXACT [UniProtKB:Q86YM7] xref: EMBL:AF093262 xref: EMBL:AY189939 xref: EMBL:AY189941 xref: EMBL:BC015502 xref: EMBL:BT009846 xref: EMBL:Y17829 xref: HGNC:HGNC:17512 xref: UniGene:Hs.591761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057307 ! HOME1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018153 name: HOMER2_human def: "Homer protein homolog 2 gene" [UniProtKB:Q9NSB8] xref: EMBL:AF081530 xref: EMBL:AF093263 xref: EMBL:AF093264 xref: EMBL:BC012109 xref: EMBL:Y19025 xref: EMBL:Y19026 xref: EMBL:Y19027 xref: EMBL:Y19028 xref: HGNC:HGNC:17513 xref: UniGene:Hs.578443 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058913 ! HOME2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018154 name: HOMER3_human def: "Homer protein homolog 3 gene" [UniProtKB:Q9NSC5] xref: EMBL:AC002985 xref: EMBL:AF093265 xref: EMBL:BC012113 xref: EMBL:Y17573 xref: EMBL:Y18895 xref: EMBL:Y18896 xref: HGNC:HGNC:17514 xref: UniGene:Hs.410683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058915 ! HOME3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018155 name: HOMEZ_human def: "Homeobox and leucine zipper protein Homez gene" [UniProtKB:Q8IX15] synonym: "KIAA1443" EXACT [UniProtKB:Q8IX15] xref: EMBL:AB037864 xref: EMBL:AF463523 xref: EMBL:BC065835 xref: HGNC:HGNC:20164 xref: UniGene:Hs.632332 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057368 ! HOMEZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018156 name: HOPX_human def: "Homeodomain-only protein gene" [UniProtKB:Q9BPY8] synonym: "HOD" EXACT [UniProtKB:Q9BPY8] synonym: "HOP" EXACT [UniProtKB:Q9BPY8] synonym: "LAGY" EXACT [UniProtKB:Q9BPY8] synonym: "NECC1" EXACT [UniProtKB:Q9BPY8] synonym: "OB1" EXACT [UniProtKB:Q9BPY8] xref: EMBL:AB059408 xref: EMBL:AB059409 xref: EMBL:AB059410 xref: EMBL:AF454763 xref: EMBL:AF492675 xref: EMBL:AF492676 xref: EMBL:AF492677 xref: EMBL:AF492678 xref: EMBL:AF492679 xref: EMBL:AF492680 xref: EMBL:AF492681 xref: EMBL:BC014225 xref: HGNC:HGNC:24961 xref: UniGene:Hs.654864 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058472 ! HOP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018157 name: HPS4_human def: "Hermansky-Pudlak syndrome 4 protein gene" [UniProtKB:Q9NQG7] synonym: "KIAA1667" EXACT [UniProtKB:Q9NQG7] xref: EMBL:AB051454 xref: EMBL:AK057648 xref: EMBL:AL365512 xref: EMBL:AL713795 xref: EMBL:AY043416 xref: EMBL:BC035614 xref: EMBL:Z99714 xref: HGNC:HGNC:15844 xref: UniGene:Hs.474436 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058867 ! HPS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018158 name: HRBL_human def: "HIV-1 Rev-binding protein-like protein gene" [UniProtKB:O95081] synonym: "RABR" EXACT [UniProtKB:O95081] xref: EMBL:AF015042 xref: EMBL:AF053356 xref: EMBL:BC009393 xref: EMBL:BC017329 xref: HGNC:HGNC:5177 xref: UniGene:Hs.521083 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054722 ! HRBL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018159 name: HRH1_human def: "Histamine H1 receptor gene" [UniProtKB:P35367] xref: EMBL:AB041380 xref: EMBL:AF026261 xref: EMBL:AY136743 xref: EMBL:D14436 xref: EMBL:D28481 xref: EMBL:X76786 xref: EMBL:Z34897 xref: HGNC:HGNC:5182 xref: UniGene:Hs.1570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055287 ! HRH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018160 name: HRH3_human def: "Histamine H3 receptor gene" [UniProtKB:Q9Y5N1] synonym: "GPCR97" EXACT [UniProtKB:Q9Y5N1] xref: EMBL:AB019000 xref: EMBL:AB045369 xref: EMBL:AF140538 xref: EMBL:AF321913 xref: EMBL:AF346903 xref: EMBL:AF346904 xref: EMBL:AF363791 xref: EMBL:AJ278250 xref: EMBL:AJ296652 xref: EMBL:AL078633 xref: EMBL:BC096840 xref: HGNC:HGNC:5184 xref: UniGene:Hs.251399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057882 ! Q8NI49_HUMAN relationship: codes_for CCO:B0057883 ! Q8NI50_HUMAN relationship: codes_for CCO:B0058036 ! Q8WXZ9_HUMAN relationship: codes_for CCO:B0059379 ! HRH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018161 name: HRH4_human def: "Histamine H4 receptor gene" [UniProtKB:Q9H3N8] synonym: "GPCR105" EXACT [UniProtKB:Q9H3N8] xref: EMBL:AB044934 xref: EMBL:AB045370 xref: EMBL:AF307973 xref: EMBL:AF312230 xref: EMBL:AF325356 xref: EMBL:AF329449 xref: EMBL:AJ298292 xref: EMBL:AY136745 xref: EMBL:BC069136 xref: EMBL:BC112348 xref: HGNC:HGNC:17383 xref: UniGene:Hs.287388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058706 ! HRH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018162 name: HRK_human def: "Activator of apoptosis harakiri gene" [UniProtKB:O00198] synonym: "BID3" EXACT [UniProtKB:O00198] xref: EMBL:U76376 xref: HGNC:HGNC:5185 xref: UniGene:Hs.87247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054298 ! HRK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018163 name: HSBP1_human def: "Heat shock factor-binding protein 1 gene" [UniProtKB:O75506] synonym: "HSF1BP" EXACT [UniProtKB:O75506] xref: EMBL:AF068754 xref: EMBL:AY320409 xref: EMBL:BC007515 xref: HGNC:HGNC:5203 xref: UniGene:Hs.250899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054646 ! HSBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018164 name: HSF5_human def: "Heat shock factor protein 5 gene" [UniProtKB:Q4G112] synonym: "HSTF5" EXACT [UniProtKB:Q4G112] xref: EMBL:AK097630 xref: EMBL:BC033017 xref: EMBL:BC033020 xref: EMBL:BC115385 xref: HGNC:HGNC:26862 xref: UniGene:Hs.380061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056315 ! HSF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018165 name: HSFX1_human def: "Heat shock transcription factor, X-linked gene" [UniProtKB:Q9UBD0] synonym: "LW-1" EXACT [UniProtKB:Q9UBD0] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059067 ! HSFX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018166 name: HSFX2_human def: "Heat shock transcription factor, X-linked gene" [UniProtKB:Q9UBD0] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059067 ! HSFX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018167 name: HSFY1_human def: "Heat shock transcription factor, Y-linked gene" [UniProtKB:Q96LI6] synonym: "HSF2L" EXACT [UniProtKB:Q96LI6] synonym: "HSFY" EXACT [UniProtKB:Q96LI6] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058272 ! HSFY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018168 name: HSFY2_human def: "Heat shock transcription factor, Y-linked gene" [UniProtKB:Q96LI6] synonym: "HSF2L" EXACT [UniProtKB:Q96LI6] synonym: "HSFY" EXACT [UniProtKB:Q96LI6] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058272 ! HSFY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018169 name: TCF12_human def: "Transcription factor 12 gene" [UniProtKB:Q99081] synonym: "HEB" EXACT [UniProtKB:Q99081] synonym: "HTF4" EXACT [UniProtKB:Q99081] xref: EMBL:BC050556 xref: EMBL:BK001049 xref: EMBL:CH471082 xref: EMBL:M65209 xref: EMBL:M80627 xref: EMBL:M83233 xref: HGNC:HGNC:11623 xref: UniGene:Hs.511504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057263 ! Q86VM2_HUMAN relationship: codes_for CCO:B0058408 ! HTF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018170 name: HTRA1_human def: "Serine protease HTRA1 precursor gene" [UniProtKB:Q92743] synonym: "HTRA" EXACT [UniProtKB:Q92743] synonym: "PRSS11" EXACT [UniProtKB:Q92743] xref: EMBL:AF097709 xref: EMBL:AF157623 xref: EMBL:Y07921 xref: HGNC:HGNC:9476 xref: UniGene:Hs.501280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058087 ! HTRA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018171 name: HTRA3_human def: "Probable serine protease HTRA3 precursor gene" [UniProtKB:P83110] synonym: "PRSP" EXACT [UniProtKB:P83110] xref: EMBL:AY040094 xref: EMBL:AY280665 xref: EMBL:AY280666 xref: EMBL:BC034390 xref: EMBL:BC035717 xref: HGNC:HGNC:30406 xref: UniGene:Hs.479119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055659 ! HTRA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018172 name: HTATSF1_human def: "HIV Tat-specific factor 1 gene" [UniProtKB:O43719] xref: EMBL:AB209303 xref: EMBL:BC009896 xref: EMBL:BT006886 xref: EMBL:U76992 xref: EMBL:Z97632 xref: HGNC:HGNC:5276 xref: UniGene:Hs.204475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054514 ! HTSF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018173 name: HN_human def: "Humanin gene" [UniProtKB:Q8IVG9] xref: EMBL:AY029066 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057344 ! HUNIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018174 name: HUNK_human def: "Hormonally up-regulated neu tumor-associated kinase gene" [UniProtKB:P57058] synonym: "MAKV" EXACT [UniProtKB:P57058] xref: EMBL:AJ271722 xref: HGNC:HGNC:13326 xref: UniGene:Hs.109437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055555 ! HUNK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018175 name: HOXA10_human def: "Homeobox protein Hox-A10 gene" [UniProtKB:P31260] synonym: "HOX1H" EXACT [UniProtKB:P31260] xref: EMBL:AC004080 xref: EMBL:AF040714 xref: EMBL:BC013971 xref: EMBL:BC071843 xref: EMBL:M30599 xref: EMBL:S69027 xref: EMBL:S69029 xref: EMBL:X58430 xref: HGNC:HGNC:5100 xref: UniGene:Hs.592166 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055235 ! HXA10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018176 name: HOXA11_human def: "Homeobox protein Hox-A11 gene" [UniProtKB:P31270] synonym: "HOX1I" EXACT [UniProtKB:P31270] xref: EMBL:AC004080 xref: EMBL:AF039307 xref: EMBL:AF071164 xref: EMBL:BC033706 xref: EMBL:BC040948 xref: HGNC:HGNC:5101 xref: UniGene:Hs.249171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055237 ! HXA11_HUMAN relationship: codes_for CCO:B0055751 ! Q05BS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018177 name: HOXA13_human def: "Homeobox protein Hox-A13 gene" [UniProtKB:P31271] synonym: "HOX1J" EXACT [UniProtKB:P31271] xref: EMBL:AC004080 xref: EMBL:U82827 xref: HGNC:HGNC:5102 xref: UniGene:Hs.592172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055238 ! HXA13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018178 name: HOXA1_human def: "Homeobox protein Hox-A1 gene" [UniProtKB:P49639] synonym: "HOX1F" EXACT [UniProtKB:P49639] xref: EMBL:AC004079 xref: EMBL:BC032547 xref: EMBL:S79869 xref: EMBL:S79871 xref: EMBL:S79910 xref: EMBL:U10421 xref: EMBL:U37431 xref: HGNC:HGNC:5099 xref: UniGene:Hs.67397 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055426 ! HXA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018179 name: HOXA2_human def: "Homeobox protein Hox-A2 gene" [UniProtKB:O43364] synonym: "HOX1K" EXACT [UniProtKB:O43364] xref: EMBL:AC004079 xref: EMBL:BC130571 xref: EMBL:CH236948 xref: EMBL:CH471073 xref: HGNC:HGNC:5103 xref: UniGene:Hs.445239 xref: UniGene:Hs.592177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054475 ! HXA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018180 name: HOXA3_human def: "Homeobox protein Hox-A3 gene" [UniProtKB:O43365] synonym: "HOX1E" EXACT [UniProtKB:O43365] xref: EMBL:AC004079 xref: EMBL:AK094200 xref: EMBL:BC015180 xref: EMBL:CH236948 xref: HGNC:HGNC:5104 xref: UniGene:Hs.659337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053750 ! A4D182_HUMAN relationship: codes_for CCO:B0054476 ! HXA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018181 name: HOXA9_human def: "Homeobox protein Hox-A9 gene" [UniProtKB:P31269] synonym: "HOX1G" EXACT [UniProtKB:P31269] xref: EMBL:AC004080 xref: EMBL:AF010258 xref: EMBL:BC006537 xref: EMBL:BC010023 xref: EMBL:BT006990 xref: EMBL:U41813 xref: EMBL:U82759 xref: HGNC:HGNC:5109 xref: UniGene:Hs.659350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055236 ! HXA9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018182 name: HOXB13_human def: "Homeobox protein Hox-B13 gene" [UniProtKB:Q92826] xref: EMBL:BC007092 xref: EMBL:BC070233 xref: EMBL:BT007410 xref: EMBL:U57052 xref: EMBL:U81599 xref: HGNC:HGNC:5112 xref: UniGene:Hs.66731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058098 ! HXB13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018183 name: HOXB2_human def: "Homeobox protein Hox-B2 gene" [UniProtKB:P14652] synonym: "HOX2H" EXACT [UniProtKB:P14652] xref: EMBL:BC074805 xref: EMBL:BC074806 xref: EMBL:X14571 xref: EMBL:X16176 xref: EMBL:X16665 xref: EMBL:X78978 xref: HGNC:HGNC:5113 xref: UniGene:Hs.514289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055027 ! HXB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018184 name: HOXB3_human def: "Homeobox protein Hox-B3 gene" [UniProtKB:P14651] synonym: "HOX2G" EXACT [UniProtKB:P14651] xref: EMBL:AF287967 xref: EMBL:AK291182 xref: EMBL:AK315102 xref: EMBL:U59298 xref: EMBL:X16175 xref: EMBL:X16667 xref: HGNC:HGNC:5114 xref: UniGene:Hs.654560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055026 ! HXB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018185 name: HOXC11_human def: "Homeobox protein Hox-C11 gene" [UniProtKB:O43248] synonym: "HOX3H" EXACT [UniProtKB:O43248] xref: EMBL:AJ000041 xref: EMBL:BC001543 xref: HGNC:HGNC:5123 xref: UniGene:Hs.127562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054462 ! HXC11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018186 name: HOXC12_human def: "Homeobox protein Hox-C12 gene" [UniProtKB:P31275] synonym: "HOC3F" EXACT [UniProtKB:P31275] synonym: "HOX3F" EXACT [UniProtKB:P31275] xref: EMBL:AF328962 xref: EMBL:AF328963 xref: HGNC:HGNC:5124 xref: UniGene:Hs.381267 xref: UniGene:Hs.587727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055240 ! HXC12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018187 name: HOXC13_human def: "Homeobox protein Hox-C13 gene" [UniProtKB:P31276] synonym: "HOX3G" EXACT [UniProtKB:P31276] xref: EMBL:AF255676 xref: EMBL:AF263466 xref: EMBL:AK024027 xref: EMBL:BC002754 xref: EMBL:BC090850 xref: EMBL:BT009908 xref: HGNC:HGNC:5125 xref: UniGene:Hs.118608 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055241 ! HXC13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018188 name: HOXC9_human def: "Homeobox protein Hox-C9 gene" [UniProtKB:P31274] synonym: "HOX3B" EXACT [UniProtKB:P31274] xref: EMBL:AK000445 xref: EMBL:AY014301 xref: EMBL:AY014302 xref: EMBL:BC053894 xref: HGNC:HGNC:5130 xref: UniGene:Hs.658823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055239 ! HXC9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018189 name: HOXD10_human def: "Homeobox protein Hox-D10 gene" [UniProtKB:P28358] synonym: "HOX4D" EXACT [UniProtKB:P28358] xref: EMBL:BC069619 xref: EMBL:BC074760 xref: EMBL:X59373 xref: HGNC:HGNC:5133 xref: UniGene:Hs.123070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055202 ! HXD10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018190 name: HOXD11_human def: "Homeobox protein Hox-D11 gene" [UniProtKB:P31277] synonym: "HOX4F" EXACT [UniProtKB:P31277] xref: EMBL:AC009336 xref: EMBL:AF154915 xref: EMBL:BC109394 xref: HGNC:HGNC:5134 xref: UniGene:Hs.421136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053864 ! A6NIS4_HUMAN relationship: codes_for CCO:B0055242 ! HXD11_HUMAN relationship: codes_for CCO:B0056035 ! Q14DW8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018191 name: HOXD12_human def: "Homeobox protein Hox-D12 gene" [UniProtKB:P35452] synonym: "HOX4H" EXACT [UniProtKB:P35452] xref: EMBL:AF154915 xref: HGNC:HGNC:5135 xref: UniGene:Hs.450028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055291 ! HXD12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018192 name: HOXD13_human def: "Homeobox protein Hox-D13 gene" [UniProtKB:P35453] synonym: "HOX4I" EXACT [UniProtKB:P35453] xref: EMBL:AB032481 xref: EMBL:AF005219 xref: EMBL:AF005220 xref: HGNC:HGNC:5136 xref: UniGene:Hs.152414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055292 ! HXD13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018193 name: HOXD1_human def: "Homeobox protein Hox-D1 gene" [UniProtKB:Q9GZZ0] synonym: "HOX4" EXACT [UniProtKB:Q9GZZ0] synonym: "HOX4G" EXACT [UniProtKB:Q9GZZ0] xref: EMBL:AF202118 xref: EMBL:AF241528 xref: HGNC:HGNC:5132 xref: UniGene:Hs.83465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058645 ! HXD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018194 name: HOXD3_human def: "Homeobox protein Hox-D3 gene" [UniProtKB:P31249] synonym: "HOX1D" EXACT [UniProtKB:P31249] synonym: "HOX4A" EXACT [UniProtKB:P31249] xref: EMBL:BC005124 xref: EMBL:BC008789 xref: EMBL:D11117 xref: EMBL:Y09980 xref: HGNC:HGNC:5137 xref: UniGene:Hs.93574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055234 ! HXD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018195 name: GCK_human def: "Glucokinase gene" [UniProtKB:P35557] xref: EMBL:AF041012 xref: EMBL:AF041013 xref: EMBL:AF041014 xref: EMBL:AF041015 xref: EMBL:AF041016 xref: EMBL:AF041017 xref: EMBL:AF041018 xref: EMBL:AF041019 xref: EMBL:AF041020 xref: EMBL:AF041021 xref: EMBL:AF041022 xref: EMBL:BC001890 xref: EMBL:M69051 xref: EMBL:M88011 xref: EMBL:M90298 xref: EMBL:M90299 xref: HGNC:HGNC:4195 xref: UniGene:Hs.1270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018508 ! HXK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018196 name: IL12RB1_human def: "Interleukin-12 receptor beta-1 chain precursor gene" [UniProtKB:P42701] synonym: "IL12R" EXACT [UniProtKB:P42701] synonym: "IL12RB" EXACT [UniProtKB:P42701] xref: EMBL:AJ297688 xref: EMBL:AJ297689 xref: EMBL:AJ297690 xref: EMBL:AJ297691 xref: EMBL:AJ297692 xref: EMBL:AJ297693 xref: EMBL:AJ297694 xref: EMBL:AJ297695 xref: EMBL:AJ297696 xref: EMBL:AJ297697 xref: EMBL:AJ297698 xref: EMBL:AJ297699 xref: EMBL:AJ297700 xref: EMBL:AJ297701 xref: EMBL:AY771996 xref: EMBL:U03187 xref: HGNC:HGNC:5971 xref: UniGene:Hs.567294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055354 ! I12R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018197 name: IL13RA1_human def: "Interleukin-13 receptor alpha-1 chain precursor gene" [UniProtKB:P78552] synonym: "IL13R" EXACT [UniProtKB:P78552] synonym: "IL13RA" EXACT [UniProtKB:P78552] xref: EMBL:BC009960 xref: EMBL:U62858 xref: EMBL:U81379 xref: EMBL:Y09328 xref: EMBL:Y10659 xref: HGNC:HGNC:5974 xref: UniGene:Hs.496646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055652 ! I13R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018198 name: IL15RA_human def: "Interleukin-15 receptor subunit alpha precursor gene" [UniProtKB:Q13261] xref: EMBL:AF035279 xref: EMBL:AL137186 xref: EMBL:AY316538 xref: EMBL:BC074726 xref: EMBL:BC121140 xref: EMBL:BC121141 xref: EMBL:CR457064 xref: EMBL:CR542023 xref: EMBL:U31628 xref: HGNC:HGNC:5978 xref: UniGene:Hs.524117 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055891 ! I15RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018199 name: IL18RAP_human def: "Interleukin-18 receptor accessory protein precursor gene" [UniProtKB:O95256] xref: EMBL:AC007248 xref: EMBL:AC007278 xref: EMBL:AF077346 xref: EMBL:BC069630 xref: EMBL:BC106765 xref: HGNC:HGNC:5989 xref: UniGene:Hs.158315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054740 ! I18RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018200 name: IL22RA2_human def: "Interleukin-22 receptor subunit alpha-2 precursor gene" [UniProtKB:Q969J5] synonym: "UNQ5793/PRO19598/PRO19822" EXACT [UniProtKB:Q969J5] xref: EMBL:AJ297262 xref: EMBL:AJ313161 xref: EMBL:AJ313162 xref: EMBL:AL050337 xref: EMBL:AY040566 xref: EMBL:AY040567 xref: EMBL:AY040568 xref: EMBL:AY044429 xref: EMBL:AY358111 xref: EMBL:AY358737 xref: EMBL:AY779023 xref: HGNC:HGNC:14901 xref: UniGene:Hs.126891 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058134 ! I22R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018201 name: IL27RA_human def: "Interleukin-27 receptor subunit alpha precursor gene" [UniProtKB:Q6UWB1] synonym: "CRL1" EXACT [UniProtKB:Q6UWB1] synonym: "TCCR" EXACT [UniProtKB:Q6UWB1] synonym: "UNQ296/PRO336" EXACT [UniProtKB:Q6UWB1] synonym: "WSX1" EXACT [UniProtKB:Q6UWB1] xref: EMBL:AF053004 xref: EMBL:AF106912 xref: EMBL:AF265242 xref: EMBL:AY358876 xref: EMBL:BC028003 xref: HGNC:HGNC:17290 xref: UniGene:Hs.132781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056952 ! I27RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018202 name: IL28RA_human def: "Interleukin-28 receptor alpha chain precursor gene" [UniProtKB:Q8IU57] synonym: "IFNLR1" EXACT [UniProtKB:Q8IU57] synonym: "LICR2" EXACT [UniProtKB:Q8IU57] xref: EMBL:AF439325 xref: EMBL:AJ534330 xref: EMBL:AK160364 xref: EMBL:AY129151 xref: EMBL:AY129152 xref: EMBL:AY129153 xref: HGNC:HGNC:18584 xref: UniGene:Hs.221375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057318 ! I28RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018203 name: IRF2BP1_human def: "Interferon regulatory factor 2-binding protein 1 gene" [UniProtKB:Q8IU81] xref: EMBL:AK223622 xref: EMBL:AL080159 xref: EMBL:AY278022 xref: EMBL:BC005834 xref: EMBL:BC038222 xref: EMBL:BC039002 xref: EMBL:BC078181 xref: EMBL:CH471126 xref: HGNC:HGNC:21728 xref: UniGene:Hs.515477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057319 ! I2BP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018204 name: IRF2BP2_human def: "Interferon regulatory factor 2-binding protein 2 gene" [UniProtKB:Q7Z5L9] xref: EMBL:AY278023 xref: EMBL:AY278024 xref: EMBL:BC020516 xref: EMBL:BC028143 xref: EMBL:BC065759 xref: HGNC:HGNC:21729 xref: UniGene:Hs.350268 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057183 ! I2BP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018205 name: INPP5B_human def: "Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor gene" [UniProtKB:P32019] xref: EMBL:AL603790 xref: EMBL:AL833055 xref: EMBL:AL929472 xref: EMBL:BC042529 xref: EMBL:BC058932 xref: EMBL:M74161 xref: HGNC:HGNC:6077 xref: UniGene:Hs.449942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055248 ! I5P2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018206 name: IAPP_human def: "Islet amyloid polypeptide precursor gene" [UniProtKB:P10997] xref: EMBL:J04422 xref: EMBL:M21785 xref: EMBL:M26650 xref: EMBL:M27503 xref: EMBL:X13859 xref: EMBL:X14902 xref: EMBL:X14903 xref: EMBL:X14904 xref: EMBL:X14905 xref: EMBL:X52818 xref: EMBL:X52819 xref: EMBL:X55634 xref: EMBL:X56030 xref: EMBL:X68830 xref: HGNC:HGNC:5329 xref: UniGene:Hs.46835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054984 ! IAPP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018207 name: IGFBP1_human def: "Insulin-like growth factor-binding protein 1 precursor gene" [UniProtKB:P08833] synonym: "IBP1" EXACT [UniProtKB:P08833] xref: EMBL:AY434089 xref: EMBL:BC035263 xref: EMBL:BT019685 xref: EMBL:M20841 xref: EMBL:M23592 xref: EMBL:M23593 xref: EMBL:M23594 xref: EMBL:M23595 xref: EMBL:M31145 xref: EMBL:M59316 xref: EMBL:M74587 xref: EMBL:X12385 xref: EMBL:X13405 xref: EMBL:X15002 xref: EMBL:Y00856 xref: HGNC:HGNC:5469 xref: UniGene:Hs.642938 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054932 ! IBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018208 name: IGFBP2_human def: "Insulin-like growth factor-binding protein 2 precursor gene" [UniProtKB:P18065] synonym: "BP2" EXACT [UniProtKB:P18065] synonym: "IBP2" EXACT [UniProtKB:P18065] xref: EMBL:A09809 xref: EMBL:AY398667 xref: EMBL:BC004312 xref: EMBL:BC009902 xref: EMBL:BC012769 xref: EMBL:BC071967 xref: EMBL:M35410 xref: EMBL:M69237 xref: EMBL:M69239 xref: EMBL:M69240 xref: EMBL:M69241 xref: EMBL:S37712 xref: EMBL:S37722 xref: EMBL:S37726 xref: EMBL:S37730 xref: EMBL:X16302 xref: HGNC:HGNC:5471 xref: UniGene:Hs.438102 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055098 ! IBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018209 name: IGFBP3_human def: "Insulin-like growth factor-binding protein 3 precursor gene" [UniProtKB:P17936] synonym: "IBP3" EXACT [UniProtKB:P17936] xref: EMBL:AC091524 xref: EMBL:BC000013 xref: EMBL:BC018962 xref: EMBL:BC064987 xref: EMBL:DQ301819 xref: EMBL:M31159 xref: EMBL:M35878 xref: EMBL:X64875 xref: HGNC:HGNC:5472 xref: UniGene:Hs.450230 xref: UniGene:Hs.697535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055094 ! IBP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018210 name: IGFBP4_human def: "Insulin-like growth factor-binding protein 4 precursor gene" [UniProtKB:P22692] synonym: "IBP4" EXACT [UniProtKB:P22692] xref: EMBL:AY442346 xref: EMBL:BC016041 xref: EMBL:BT019892 xref: EMBL:M38177 xref: EMBL:M62403 xref: EMBL:U20982 xref: HGNC:HGNC:5473 xref: UniGene:Hs.462998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055149 ! IBP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018211 name: IGFBP5_human def: "Insulin-like growth factor-binding protein 5 precursor gene" [UniProtKB:P24593] synonym: "IBP5" EXACT [UniProtKB:P24593] xref: EMBL:AF055033 xref: EMBL:AY534685 xref: EMBL:BC011453 xref: EMBL:BT019706 xref: EMBL:BT019707 xref: EMBL:L27556 xref: EMBL:L27557 xref: EMBL:L27558 xref: EMBL:L27559 xref: EMBL:M62782 xref: EMBL:M65062 xref: HGNC:HGNC:5474 xref: UniGene:Hs.635441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055174 ! IBP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018212 name: IGFBP6_human def: "Insulin-like growth factor-binding protein 6 precursor gene" [UniProtKB:P24592] synonym: "IBP6" EXACT [UniProtKB:P24592] xref: EMBL:AJ006952 xref: EMBL:AY443494 xref: EMBL:BC003507 xref: EMBL:BC005007 xref: EMBL:BC010162 xref: EMBL:BC011708 xref: EMBL:M62402 xref: EMBL:M69054 xref: HGNC:HGNC:5475 xref: UniGene:Hs.274313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055173 ! IBP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018213 name: IGFBP7_human def: "Insulin-like growth factor-binding protein 7 precursor gene" [UniProtKB:Q16270] synonym: "MAC25" EXACT [UniProtKB:Q16270] synonym: "PSF" EXACT [UniProtKB:Q16270] xref: EMBL:AY518539 xref: EMBL:BC017201 xref: EMBL:BC066339 xref: EMBL:BT006654 xref: EMBL:L19182 xref: EMBL:S75725 xref: HGNC:HGNC:5476 xref: UniGene:Hs.479808 xref: UniGene:Hs.696434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056131 ! IBP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018214 name: IGFBPL1_human def: "Insulin-like growth factor-binding protein-like 1 precursor gene" [UniProtKB:Q8WX77] synonym: "IGFBPRP4" EXACT [UniProtKB:Q8WX77] xref: EMBL:AL135785 xref: EMBL:CH471071 xref: HGNC:HGNC:20081 xref: UniGene:Hs.349705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058010 ! IBPL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018215 name: ICOSLG_human def: "ICOS ligand precursor gene" [UniProtKB:O75144] synonym: "B7H2" EXACT [UniProtKB:O75144] synonym: "B7RP1" EXACT [UniProtKB:O75144] synonym: "ICOSL" EXACT [UniProtKB:O75144] synonym: "KIAA0653" EXACT [UniProtKB:O75144] xref: EMBL:AB014553 xref: EMBL:AF199028 xref: EMBL:AF216749 xref: EMBL:AF289028 xref: EMBL:AX100595 xref: EMBL:BC064637 xref: HGNC:HGNC:17087 xref: UniGene:Hs.14155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054605 ! ICOSL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018216 name: ID1_human def: "DNA-binding protein inhibitor ID-1 gene" [UniProtKB:P41134] synonym: "ID" EXACT [UniProtKB:P41134] xref: EMBL:AL110115 xref: EMBL:AL117381 xref: EMBL:BC000613 xref: EMBL:BC012420 xref: EMBL:BT007443 xref: EMBL:D13889 xref: EMBL:D13890 xref: EMBL:S78825 xref: EMBL:S78986 xref: EMBL:U57645 xref: EMBL:X77956 xref: HGNC:HGNC:5360 xref: UniGene:Hs.504609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022223 ! ID1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018217 name: ID4_human def: "DNA-binding protein inhibitor ID-4 gene" [UniProtKB:P47928] xref: EMBL:AL022726 xref: EMBL:BC014941 xref: EMBL:U16153 xref: EMBL:U28368 xref: EMBL:Y07958 xref: HGNC:HGNC:5363 xref: UniGene:Hs.519601 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022226 ! ID4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018218 name: IER3_human def: "Radiation-inducible immediate-early gene IEX-1 gene" [UniProtKB:P46695] synonym: "DIF2" EXACT [UniProtKB:P46695] synonym: "IEX1" EXACT [UniProtKB:P46695] synonym: "PRG1" EXACT [UniProtKB:P46695] xref: EMBL:BA000025 xref: EMBL:BC000844 xref: EMBL:BC005080 xref: EMBL:BT006703 xref: EMBL:S81914 xref: EMBL:X96438 xref: EMBL:Y14551 xref: HGNC:HGNC:5392 xref: UniGene:Hs.591785 xref: UniGene:Hs.696650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055379 ! IEX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018219 name: IFI16_human def: "Gamma-interferon-inducible protein Ifi-16 gene" [UniProtKB:Q16666] synonym: "IFNGIP1" EXACT [UniProtKB:Q16666] xref: EMBL:AB208989 xref: EMBL:AF208043 xref: EMBL:AK094968 xref: EMBL:AL359753 xref: EMBL:AY138863 xref: EMBL:BC017059 xref: EMBL:M63838 xref: EMBL:S75417 xref: EMBL:S75419 xref: EMBL:S75421 xref: EMBL:S75423 xref: EMBL:S75424 xref: EMBL:S75426 xref: EMBL:S75429 xref: EMBL:S75431 xref: EMBL:S75433 xref: HGNC:HGNC:5395 xref: UniGene:Hs.380250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056172 ! IF16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018220 name: IGF2BP1_human def: "Insulin-like growth factor 2 mRNA-binding protein 1 gene" [UniProtKB:Q9NZI8] synonym: "CRDBP" EXACT [UniProtKB:Q9NZI8] synonym: "VICKZ1" EXACT [UniProtKB:Q9NZI8] synonym: "ZBP1" EXACT [UniProtKB:Q9NZI8] xref: EMBL:AF198254 xref: HGNC:HGNC:28866 xref: UniGene:Hs.144936 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059000 ! IF2B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018221 name: IGF2BP2_human def: "Insulin-like growth factor 2 mRNA-binding protein 2 gene" [UniProtKB:Q9Y6M1] synonym: "IMP2" EXACT [UniProtKB:Q9Y6M1] synonym: "VICKZ2" EXACT [UniProtKB:Q9Y6M1] xref: EMBL:AF057352 xref: HGNC:HGNC:28867 xref: UniGene:Hs.35354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059410 ! IF2B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018222 name: IGF2BP3_human def: "Insulin-like growth factor 2 mRNA-binding protein 3 gene" [UniProtKB:O00425] synonym: "IMP3" EXACT [UniProtKB:O00425] synonym: "KOC1" EXACT [UniProtKB:O00425] synonym: "VICKZ3" EXACT [UniProtKB:O00425] xref: EMBL:BC051296 xref: EMBL:BC065269 xref: EMBL:BX640800 xref: EMBL:BX648488 xref: EMBL:U76705 xref: EMBL:U97188 xref: HGNC:HGNC:28868 xref: UniGene:Hs.700696 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054319 ! IF2B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018223 name: MTIF2_human def: "Translation initiation factor IF-2, mitochondrial precursor gene" [UniProtKB:P46199] xref: EMBL:AF494407 xref: EMBL:AF495543 xref: EMBL:AF495544 xref: EMBL:AF495545 xref: EMBL:AF495546 xref: EMBL:L34600 xref: HGNC:HGNC:7441 xref: UniGene:Hs.149894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023063 ! IF2M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018224 name: EIF5B_human def: "Eukaryotic translation initiation factor 5B gene" [UniProtKB:O60841] synonym: "IF2" EXACT [UniProtKB:O60841] synonym: "KIAA0741" EXACT [UniProtKB:O60841] xref: EMBL:AB018284 xref: EMBL:AF078035 xref: EMBL:AJ006412 xref: EMBL:AJ006776 xref: EMBL:AL133563 xref: HGNC:HGNC:30793 xref: UniGene:Hs.158688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054581 ! IF2P_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018225 name: MTIF3_human def: "Translation initiation factor IF-3, mitochondrial precursor gene" [UniProtKB:Q9H2K0] synonym: "DC38" EXACT [UniProtKB:Q9H2K0] xref: EMBL:AF265440 xref: EMBL:AF410851 xref: EMBL:AL137059 xref: EMBL:BC039599 xref: EMBL:BC046166 xref: HGNC:HGNC:29788 xref: UniGene:Hs.534582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058687 ! IF3M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018226 name: EIF4A3_human def: "Eukaryotic initiation factor 4A-III gene" [UniProtKB:P38919] synonym: "DDX48" EXACT [UniProtKB:P38919] synonym: "KIAA0111" EXACT [UniProtKB:P38919] xref: EMBL:BC003662 xref: EMBL:BC004386 xref: EMBL:BC011151 xref: EMBL:D21853 xref: EMBL:X79538 xref: HGNC:HGNC:18683 xref: UniGene:Hs.389649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055320 ! IF4A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018227 name: EIF4E2_human def: "Eukaryotic translation initiation factor 4E type 2 gene" [UniProtKB:O60573] synonym: "EIF4EL3" EXACT [UniProtKB:O60573] xref: EMBL:AF038957 xref: EMBL:AF047695 xref: EMBL:AF068117 xref: EMBL:BC005392 xref: EMBL:BC005874 xref: EMBL:BC021226 xref: EMBL:BC021690 xref: HGNC:HGNC:3293 xref: UniGene:Hs.292026 xref: UniGene:Hs.700929 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054567 ! IF4E2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018228 name: EIF4E3_human def: "Eukaryotic translation initiation factor 4E type 3 gene" [UniProtKB:Q8N5X7] xref: EMBL:AC134770 xref: EMBL:BC031289 xref: EMBL:BC068443 xref: HGNC:HGNC:31837 xref: UniGene:Hs.655608 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057481 ! IF4E3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018229 name: EIF4G1_human def: "Eukaryotic translation initiation factor 4 gamma 1 gene" [UniProtKB:Q04637] synonym: "EIF4F" EXACT [UniProtKB:Q04637] synonym: "EIF4G" EXACT [UniProtKB:Q04637] synonym: "EIF4GI" EXACT [UniProtKB:Q04637] xref: EMBL:AF002816 xref: EMBL:AF004836 xref: EMBL:AF104913 xref: EMBL:AF281070 xref: EMBL:AJ001046 xref: EMBL:AK131407 xref: EMBL:AY082886 xref: EMBL:BX647812 xref: EMBL:D12686 xref: HGNC:HGNC:3296 xref: UniGene:Hs.433750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055731 ! IF4G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018230 name: EIF4G3_human def: "Eukaryotic translation initiation factor 4 gamma 3 gene" [UniProtKB:O43432] xref: EMBL:AF012072 xref: EMBL:AL358392 xref: EMBL:AL606477 xref: EMBL:AL627311 xref: EMBL:BC030578 xref: EMBL:CH471134 xref: EMBL:Z34918 xref: HGNC:HGNC:3298 xref: UniGene:Hs.467084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016344 ! IF4G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018231 name: EIF4H_human def: "Eukaryotic translation initiation factor 4H gene" [UniProtKB:Q15056] synonym: "KIAA0038" EXACT [UniProtKB:Q15056] synonym: "WBSCR1" EXACT [UniProtKB:Q15056] synonym: "WSCR1" EXACT [UniProtKB:Q15056] xref: EMBL:AF045555 xref: EMBL:BC010021 xref: EMBL:BC021214 xref: EMBL:BC066928 xref: EMBL:D26068 xref: HGNC:HGNC:12741 xref: UniGene:Hs.520943 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056040 ! IF4H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018232 name: IFI6_human def: "Interferon alpha-inducible protein 6 precursor gene" [UniProtKB:P09912] synonym: "G1P3" EXACT [UniProtKB:P09912] xref: EMBL:BC011601 xref: EMBL:BC015603 xref: EMBL:BT006850 xref: EMBL:U22970 xref: EMBL:X02492 xref: HGNC:HGNC:4054 xref: UniGene:Hs.511731 xref: UniGene:Hs.523847 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054951 ! IFI6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018233 name: IFIH1_human def: "Interferon-induced helicase C domain-containing protein 1 gene" [UniProtKB:Q9BYX4] synonym: "MDA5" EXACT [UniProtKB:Q9BYX4] synonym: "RH116" EXACT [UniProtKB:Q9BYX4] xref: EMBL:AF095844 xref: EMBL:AK056293 xref: EMBL:AY017378 xref: EMBL:BC046208 xref: EMBL:BC078180 xref: EMBL:BC111750 xref: HGNC:HGNC:18873 xref: UniGene:Hs.163173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058587 ! IFIH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018234 name: IFT52_human def: "Intraflagellar transport protein 52 homolog gene" [UniProtKB:Q9Y366] synonym: "C20orf9" EXACT [UniProtKB:Q9Y366] synonym: "CGI-53" EXACT [UniProtKB:Q9Y366] synonym: "NGD5" EXACT [UniProtKB:Q9Y366] xref: EMBL:AF151811 xref: EMBL:AL121886 xref: EMBL:BC039831 xref: EMBL:Z98752 xref: HGNC:HGNC:15901 xref: UniGene:Hs.444332 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059332 ! IFT52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018235 name: IFT57_human def: "Intraflagellar transport protein 57 homolog gene" [UniProtKB:Q9NWB7] synonym: "DERP8" EXACT [UniProtKB:Q9NWB7] synonym: "ESRRBL1" EXACT [UniProtKB:Q9NWB7] synonym: "HIPPI" EXACT [UniProtKB:Q9NWB7] xref: EMBL:AB014762 xref: EMBL:AF139576 xref: EMBL:AF245220 xref: EMBL:AK001009 xref: EMBL:BC009690 xref: EMBL:BC011899 xref: EMBL:CH471052 xref: EMBL:CR457251 xref: HGNC:HGNC:17367 xref: UniGene:Hs.412196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058936 ! IFT57_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018236 name: IFT88_human def: "Intraflagellar transport protein 88 homolog gene" [UniProtKB:Q13099] synonym: "TG737" EXACT [UniProtKB:Q13099] synonym: "TTC10" EXACT [UniProtKB:Q13099] xref: EMBL:AL161772 xref: EMBL:AL590096 xref: EMBL:BC030776 xref: EMBL:U20362 xref: HGNC:HGNC:20606 xref: UniGene:Hs.187376 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055873 ! IFT88_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018237 name: IGBP1_human def: "Immunoglobulin-binding protein 1 gene" [UniProtKB:P78318] synonym: "IBP1" EXACT [UniProtKB:P78318] xref: EMBL:AL139111 xref: EMBL:AL158141 xref: EMBL:BC004137 xref: EMBL:BT006736 xref: EMBL:Y08915 xref: HGNC:HGNC:5461 xref: UniGene:Hs.496267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055637 ! IGBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018238 name: IGSF11_human def: "Immunoglobulin superfamily member 11 precursor gene" [UniProtKB:Q5DX21] synonym: "BTIGSF" EXACT [UniProtKB:Q5DX21] synonym: "CXADRL1" EXACT [UniProtKB:Q5DX21] synonym: "VSIG3" EXACT [UniProtKB:Q5DX21] xref: EMBL:AB071618 xref: EMBL:AK097667 xref: EMBL:AL834256 xref: EMBL:BC034411 xref: HGNC:HGNC:16669 xref: UniGene:Hs.112873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056422 ! IGS11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018239 name: IGSF1_human def: "Immunoglobulin superfamily member 1 precursor gene" [UniProtKB:Q8N6C5] synonym: "IGDC1" EXACT [UniProtKB:Q8N6C5] synonym: "KIAA0364" EXACT [UniProtKB:Q8N6C5] synonym: "PGSF2" EXACT [UniProtKB:Q8N6C5] xref: EMBL:AB002362 xref: EMBL:AB058894 xref: EMBL:AF034198 xref: EMBL:AL137369 xref: EMBL:Y10523 xref: HGNC:HGNC:5948 xref: UniGene:Hs.22111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057486 ! IGSF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018240 name: IGSF2_human def: "Immunoglobulin superfamily member 2 precursor gene" [UniProtKB:Q93033] synonym: "CD101" EXACT [UniProtKB:Q93033] synonym: "EWI101" EXACT [UniProtKB:Q93033] synonym: "V7" EXACT [UniProtKB:Q93033] xref: EMBL:Z33642 xref: HGNC:HGNC:5949 xref: UniGene:Hs.654598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058120 ! IGSF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018241 name: IGSF6_human def: "Immunoglobulin superfamily member 6 precursor gene" [UniProtKB:O95976] synonym: "DORA" EXACT [UniProtKB:O95976] xref: EMBL:AJ223183 xref: EMBL:BC017844 xref: HGNC:HGNC:5953 xref: UniGene:Hs.530902 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054812 ! IGSF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018242 name: IGSF8_human def: "Immunoglobulin superfamily member 8 precursor gene" [UniProtKB:Q969P0] synonym: "CD81P3" EXACT [UniProtKB:Q969P0] synonym: "EWI2" EXACT [UniProtKB:Q969P0] synonym: "KCT4" EXACT [UniProtKB:Q969P0] xref: EMBL:AF311906 xref: EMBL:AF407274 xref: EMBL:AK055843 xref: EMBL:AY044845 xref: EMBL:AY157579 xref: EMBL:BC004108 xref: EMBL:BC053881 xref: HGNC:HGNC:17813 xref: UniGene:Hs.332012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058136 ! IGSF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018243 name: IHH_human def: "Indian hedgehog protein precursor gene" [UniProtKB:Q14623] xref: EMBL:AB018076 xref: EMBL:BC034757 xref: EMBL:L38517 xref: HGNC:HGNC:5956 xref: UniGene:Hs.654504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056004 ! IHH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018244 name: IRAK1BP1_human def: "Interleukin-1 receptor-associated kinase 1-binding protein 1 gene" [UniProtKB:Q5VVH5] xref: EMBL:AL450327 xref: EMBL:BC112253 xref: EMBL:BC112255 xref: EMBL:CH471051 xref: HGNC:HGNC:17368 xref: UniGene:Hs.656212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056658 ! IKBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018245 name: NFKBIZ_human def: "NF-kappa-B inhibitor zeta gene" [UniProtKB:Q9BYH8] synonym: "IKBZ" EXACT [UniProtKB:Q9BYH8] synonym: "INAP" EXACT [UniProtKB:Q9BYH8] synonym: "MAIL" EXACT [UniProtKB:Q9BYH8] xref: EMBL:AB037925 xref: EMBL:AF548362 xref: EMBL:AK091782 xref: EMBL:BC060800 xref: EMBL:CH471052 xref: EMBL:DQ224339 xref: HGNC:HGNC:29805 xref: UniGene:Hs.319171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058579 ! IKBZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018246 name: IKZF5_human def: "Zinc finger protein Pegasus gene" [UniProtKB:Q9H5V7] synonym: "ZNFN1A5" EXACT [UniProtKB:Q9H5V7] xref: EMBL:AF230808 xref: EMBL:AK026626 xref: EMBL:BC022564 xref: EMBL:BX647958 xref: EMBL:CH471066 xref: EMBL:CR749800 xref: HGNC:HGNC:14283 xref: UniGene:Hs.501289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058729 ! IKZF5_HUMAN relationship: codes_for CCO:B0062877 ! Q8TBE5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018247 name: IL10_human def: "Interleukin-10 precursor gene" [UniProtKB:P22301] xref: EMBL:AF418271 xref: EMBL:AY029171 xref: EMBL:M57627 xref: EMBL:U16720 xref: HGNC:HGNC:5962 xref: UniGene:Hs.193717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055142 ! IL10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018248 name: IL11_human def: "Interleukin-11 precursor gene" [UniProtKB:P20809] xref: EMBL:AY207429 xref: EMBL:BC012506 xref: EMBL:M57765 xref: EMBL:X58377 xref: HGNC:HGNC:5966 xref: UniGene:Hs.467304 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055126 ! IL11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018249 name: IL12A_human def: "Interleukin-12 subunit alpha precursor gene" [UniProtKB:P29459] synonym: "NKSF1" EXACT [UniProtKB:P29459] xref: EMBL:AC010370 xref: EMBL:AF404773 xref: EMBL:M65271 xref: EMBL:M65291 xref: HGNC:HGNC:5969 xref: UniGene:Hs.673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061988 ! IL12A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018250 name: IL15_human def: "Interleukin-15 precursor gene" [UniProtKB:P40933] xref: EMBL:AF031167 xref: EMBL:BC018149 xref: EMBL:BC100963 xref: EMBL:U14407 xref: EMBL:X91233 xref: EMBL:X94222 xref: EMBL:X94223 xref: EMBL:Y09908 xref: EMBL:Z38000 xref: HGNC:HGNC:5977 xref: UniGene:Hs.654378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055332 ! IL15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018251 name: IL17C_human def: "Interleukin-17C precursor gene" [UniProtKB:Q9P0M4] synonym: "UNQ561/PRO1122" EXACT [UniProtKB:Q9P0M4] xref: EMBL:AF142410 xref: EMBL:AF152099 xref: EMBL:AY358471 xref: EMBL:BC069152 xref: EMBL:BC101835 xref: EMBL:BC112196 xref: HGNC:HGNC:5983 xref: UniGene:Hs.278911 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059031 ! IL17C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018252 name: IL18R1_human def: "Interleukin-18 receptor 1 precursor gene" [UniProtKB:Q13478] synonym: "IL1RRP" EXACT [UniProtKB:Q13478] xref: EMBL:AC007248 xref: EMBL:BC069575 xref: EMBL:BC093975 xref: EMBL:BC093977 xref: EMBL:U43672 xref: HGNC:HGNC:5988 xref: UniGene:Hs.469521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055913 ! IL18R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018253 name: IL18_human def: "Interleukin-18 precursor gene" [UniProtKB:Q14116] synonym: "IGIF" EXACT [UniProtKB:Q14116] synonym: "IL1F4" EXACT [UniProtKB:Q14116] xref: EMBL:AF077611 xref: EMBL:AY044641 xref: EMBL:BC007007 xref: EMBL:BC007461 xref: EMBL:D49950 xref: EMBL:U90434 xref: HGNC:HGNC:5986 xref: UniGene:Hs.83077 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055957 ! IL18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018254 name: IL19_human def: "Interleukin-19 precursor gene" [UniProtKB:Q9UHD0] synonym: "ZMDA1" EXACT [UniProtKB:Q9UHD0] xref: EMBL:AF192498 xref: EMBL:AF276915 xref: EMBL:AF390905 xref: EMBL:AF453946 xref: EMBL:AL049615 xref: EMBL:AY040367 xref: HGNC:HGNC:5990 xref: UniGene:Hs.661017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059136 ! IL19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018255 name: IL1RAP_human def: "Interleukin-1 receptor accessory protein precursor gene" [UniProtKB:Q9NPH3] xref: EMBL:AB006537 xref: EMBL:AF016261 xref: EMBL:AF029213 xref: EMBL:AF167335 xref: EMBL:AF167336 xref: EMBL:AF167337 xref: EMBL:AF167338 xref: EMBL:AF167339 xref: EMBL:AF167340 xref: EMBL:AF167341 xref: EMBL:AF167342 xref: EMBL:AF167343 xref: EMBL:AF487335 xref: EMBL:AF538730 xref: EMBL:AF538731 xref: EMBL:AF538732 xref: EMBL:AF538733 xref: EMBL:AF538734 xref: EMBL:BC053621 xref: EMBL:EF591790 xref: HGNC:HGNC:5995 xref: UniGene:Hs.478673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054287 ! B1NLD0_HUMAN relationship: codes_for CCO:B0058853 ! IL1AP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018256 name: IL20_human def: "Interleukin-20 precursor gene" [UniProtKB:Q9NYY1] synonym: "UNQ852/PRO1801" EXACT [UniProtKB:Q9NYY1] synonym: "ZCYTO10" EXACT [UniProtKB:Q9NYY1] xref: EMBL:AF224266 xref: EMBL:AF402002 xref: EMBL:AY358320 xref: EMBL:BC069311 xref: EMBL:BC069364 xref: EMBL:BC069398 xref: EMBL:BC069425 xref: EMBL:BC069449 xref: EMBL:BC069487 xref: EMBL:BC069523 xref: EMBL:BC069559 xref: EMBL:BC074948 xref: EMBL:BC074949 xref: EMBL:BC117386 xref: EMBL:BC117390 xref: HGNC:HGNC:6002 xref: UniGene:Hs.272373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058987 ! IL20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018257 name: IL21_human def: "Interleukin-21 precursor gene" [UniProtKB:Q9HBE4] xref: EMBL:AF254069 xref: EMBL:AY763518 xref: EMBL:BC066258 xref: EMBL:BC066259 xref: EMBL:BC066260 xref: EMBL:BC066261 xref: EMBL:BC066262 xref: EMBL:BC069124 xref: EMBL:DQ645417 xref: HGNC:HGNC:6005 xref: UniGene:Hs.567559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058783 ! IL21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018258 name: IL22_human def: "Interleukin-22 precursor gene" [UniProtKB:Q9GZX6] synonym: "ILTIF" EXACT [UniProtKB:Q9GZX6] synonym: "UNQ3099/PRO10096" EXACT [UniProtKB:Q9GZX6] xref: EMBL:AF279437 xref: EMBL:AF387519 xref: EMBL:AJ277247 xref: EMBL:AJ277248 xref: EMBL:AY358890 xref: EMBL:BC066263 xref: EMBL:BC067510 xref: EMBL:BC069112 xref: EMBL:BC069308 xref: EMBL:BC070261 xref: HGNC:HGNC:14900 xref: UniGene:Hs.287369 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058642 ! IL22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018259 name: IL27_human def: "Interleukin-27 subunit alpha precursor gene" [UniProtKB:Q8NEV9] synonym: "IL27A" EXACT [UniProtKB:Q8NEV9] xref: EMBL:AY099296 xref: EMBL:BC062422 xref: EMBL:CH471279 xref: EMBL:EF064720 xref: HGNC:HGNC:19157 xref: UniGene:Hs.528111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057596 ! IL27A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018260 name: EBI3_human def: "Interleukin-27 subunit beta precursor gene" [UniProtKB:Q14213] synonym: "IL27B" EXACT [UniProtKB:Q14213] xref: EMBL:AC005578 xref: EMBL:BC015364 xref: EMBL:BC046112 xref: EMBL:L08187 xref: HGNC:HGNC:3129 xref: UniGene:Hs.501452 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055972 ! IL27B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018261 name: IL29_human def: "Interleukin-29 precursor gene" [UniProtKB:Q8IU54] synonym: "IFNL1" EXACT [UniProtKB:Q8IU54] synonym: "ZCYTO21" EXACT [UniProtKB:Q8IU54] xref: EMBL:AY129150 xref: EMBL:AY184372 xref: EMBL:AY336716 xref: EMBL:BC074985 xref: EMBL:BC117482 xref: EMBL:BC126183 xref: HGNC:HGNC:18363 xref: UniGene:Hs.406745 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057317 ! IL29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018262 name: IL2RG_human def: "Cytokine receptor common gamma chain precursor gene" [UniProtKB:P31785] xref: EMBL:AY692262 xref: EMBL:BC014972 xref: EMBL:D11086 xref: EMBL:L12176 xref: EMBL:L12177 xref: EMBL:L12178 xref: EMBL:L12179 xref: EMBL:L12180 xref: EMBL:L12181 xref: EMBL:L12182 xref: EMBL:L12183 xref: EMBL:L19546 xref: HGNC:HGNC:6010 xref: UniGene:Hs.84 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055246 ! IL2RG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018263 name: IL3_human def: "Interleukin-3 precursor gene" [UniProtKB:P08700] xref: EMBL:AC004511 xref: EMBL:AF365976 xref: EMBL:BC066272 xref: EMBL:BC069472 xref: EMBL:M14743 xref: EMBL:M17115 xref: EMBL:M20137 xref: HGNC:HGNC:6011 xref: UniGene:Hs.694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054931 ! IL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018264 name: IL4R_human def: "Interleukin-4 receptor alpha chain precursor gene" [UniProtKB:P24394] synonym: "582J2.1" EXACT [UniProtKB:P24394] synonym: "IL4RA" EXACT [UniProtKB:P24394] xref: EMBL:AC004525 xref: EMBL:AF421855 xref: EMBL:AJ293647 xref: EMBL:AJ293648 xref: EMBL:AJ293649 xref: EMBL:AJ293650 xref: EMBL:AJ293651 xref: EMBL:AJ293652 xref: EMBL:AJ293653 xref: EMBL:AJ293654 xref: EMBL:X52425 xref: HGNC:HGNC:6015 xref: UniGene:Hs.513457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055171 ! IL4RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018265 name: IL4_human def: "Interleukin-4 precursor gene" [UniProtKB:P05112] xref: EMBL:AF395008 xref: EMBL:BC067514 xref: EMBL:BC070123 xref: EMBL:M13982 xref: EMBL:M23442 xref: EMBL:X06750 xref: EMBL:X81851 xref: HGNC:HGNC:6014 xref: UniGene:Hs.73917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054894 ! IL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018266 name: IL5RA_human def: "Interleukin-5 receptor subunit alpha precursor gene" [UniProtKB:Q01344] synonym: "IL5R" EXACT [UniProtKB:Q01344] xref: EMBL:AY642135 xref: EMBL:M75914 xref: EMBL:M96651 xref: EMBL:M96652 xref: HGNC:HGNC:6017 xref: UniGene:Hs.68876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055688 ! IL5RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018267 name: IL5_human def: "Interleukin-5 precursor gene" [UniProtKB:P05113] xref: EMBL:AF353265 xref: EMBL:BC066282 xref: EMBL:J02971 xref: EMBL:J03478 xref: EMBL:X04688 xref: EMBL:X12705 xref: EMBL:X12706 xref: HGNC:HGNC:6016 xref: UniGene:Hs.2247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054895 ! IL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018268 name: IL6R_human def: "Interleukin-6 receptor subunit alpha precursor gene" [UniProtKB:P08887] xref: EMBL:AK223582 xref: EMBL:AL162591 xref: EMBL:BC089410 xref: EMBL:S72848 xref: EMBL:X12830 xref: EMBL:X58298 xref: HGNC:HGNC:6019 xref: UniGene:Hs.695954 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054933 ! IL6RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018269 name: IL6_human def: "Interleukin-6 precursor gene" [UniProtKB:P05231] synonym: "IFNB2" EXACT [UniProtKB:P05231] xref: EMBL:AF372214 xref: EMBL:BC015511 xref: EMBL:M14584 xref: EMBL:M18403 xref: EMBL:M29150 xref: EMBL:M54894 xref: EMBL:S56892 xref: EMBL:X04402 xref: EMBL:X04403 xref: EMBL:X04430 xref: EMBL:X04602 xref: EMBL:Y00081 xref: HGNC:HGNC:6018 xref: UniGene:Hs.654458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054899 ! IL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018270 name: IL7R_human def: "Interleukin-7 receptor subunit alpha precursor gene" [UniProtKB:P16871] xref: EMBL:AF043123 xref: EMBL:AF043124 xref: EMBL:AF043125 xref: EMBL:AF043126 xref: EMBL:AF043127 xref: EMBL:AF043128 xref: EMBL:AF043129 xref: EMBL:AY449709 xref: EMBL:BC067540 xref: EMBL:M29696 xref: HGNC:HGNC:6024 xref: UniGene:Hs.591742 xref: UniGene:Hs.635723 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055060 ! IL7RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018271 name: IL9R_human def: "Interleukin-9 receptor precursor gene" [UniProtKB:Q01113] xref: EMBL:AJ271736 xref: EMBL:AY071830 xref: EMBL:L39064 xref: EMBL:M84747 xref: EMBL:S71404 xref: EMBL:S71420 xref: HGNC:HGNC:6030 xref: UniGene:Hs.406228 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055686 ! IL9R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018272 name: IL9_human def: "Interleukin-9 precursor gene" [UniProtKB:P15248] xref: EMBL:AC002428 xref: EMBL:AC004763 xref: EMBL:AF361105 xref: EMBL:BC066283 xref: EMBL:BC066285 xref: EMBL:BC066286 xref: EMBL:M30134 xref: EMBL:M30135 xref: EMBL:M86593 xref: EMBL:S63356 xref: EMBL:X17543 xref: HGNC:HGNC:6029 xref: UniGene:Hs.960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055032 ! IL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018273 name: ILF2_human def: "Interleukin enhancer-binding factor 2 gene" [UniProtKB:Q12905] synonym: "NF45" EXACT [UniProtKB:Q12905] synonym: "PRO3063" EXACT [UniProtKB:Q12905] xref: EMBL:AF113702 xref: EMBL:AL592150 xref: EMBL:AL713889 xref: EMBL:AY099265 xref: EMBL:BC000382 xref: EMBL:CH471121 xref: EMBL:U10323 xref: HGNC:HGNC:6037 xref: UniGene:Hs.75117 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055855 ! ILF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018274 name: ILK_human def: "Integrin-linked protein kinase gene" [UniProtKB:Q13418] synonym: "ILK1" EXACT [UniProtKB:Q13418] synonym: "ILK2" EXACT [UniProtKB:Q13418] xref: EMBL:AF244139 xref: EMBL:AJ277481 xref: EMBL:AJ404847 xref: EMBL:BC001554 xref: EMBL:CR407673 xref: EMBL:CR749220 xref: EMBL:U40282 xref: HGNC:HGNC:6040 xref: UniGene:Hs.5158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055907 ! ILK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018275 name: IL1RL1_human def: "Interleukin-1 receptor-like 1 precursor gene" [UniProtKB:Q01638] synonym: "DER4" EXACT [UniProtKB:Q01638] synonym: "ST2" EXACT [UniProtKB:Q01638] synonym: "T1" EXACT [UniProtKB:Q01638] xref: EMBL:AB012701 xref: EMBL:AB029084 xref: EMBL:AC007248 xref: EMBL:BC030975 xref: EMBL:D12763 xref: EMBL:D12764 xref: HGNC:HGNC:5998 xref: UniGene:Hs.66 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055691 ! ILRL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018276 name: IL1RL2_human def: "Interleukin-1 receptor-like 2 precursor gene" [UniProtKB:Q9HB29] synonym: "IL1RRP2" EXACT [UniProtKB:Q9HB29] xref: EMBL:AC007248 xref: EMBL:AC007271 xref: EMBL:AF284434 xref: EMBL:BC107064 xref: EMBL:DQ131903 xref: EMBL:U49065 xref: HGNC:HGNC:5999 xref: UniGene:Hs.659863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053764 ! A4FU63_HUMAN relationship: codes_for CCO:B0058773 ! ILRL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018277 name: IMPDH2_human def: "Inosine-5'-monophosphate dehydrogenase 2 gene" [UniProtKB:P12268] synonym: "IMPD2" EXACT [UniProtKB:P12268] xref: EMBL:BC006124 xref: EMBL:BC012840 xref: EMBL:BC015567 xref: EMBL:J04208 xref: EMBL:L08114 xref: EMBL:L33842 xref: EMBL:L39210 xref: HGNC:HGNC:6053 xref: UniGene:Hs.654400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054998 ! IMDH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018278 name: IMPACT_human def: "Protein IMPACT gene" [UniProtKB:Q9P2X3] xref: EMBL:AB026264 xref: EMBL:AC007922 xref: EMBL:AC020937 xref: EMBL:AF208694 xref: EMBL:AF232229 xref: EMBL:AK292533 xref: EMBL:BC034016 xref: EMBL:BC036074 xref: EMBL:CH471088 xref: HGNC:HGNC:20387 xref: UniGene:Hs.515317 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059062 ! IMPCT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018279 name: INO80B_human def: "INO80 complex subunit B gene" [UniProtKB:Q9C086] synonym: "HMGA1L4" EXACT [UniProtKB:Q9C086] synonym: "PAPA1" EXACT [UniProtKB:Q9C086] synonym: "ZNHIT4" EXACT [UniProtKB:Q9C086] xref: EMBL:AB054538 xref: EMBL:BC050666 xref: EMBL:BC064425 xref: HGNC:HGNC:13324 xref: UniGene:Hs.410786 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061990 ! IN80B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018280 name: INO80D_human def: "INO80 complex subunit D gene" [UniProtKB:Q53TQ3] xref: EMBL:AC007383 xref: EMBL:AC007679 xref: EMBL:AC092677 xref: EMBL:AK000316 xref: EMBL:AK096585 xref: EMBL:BC004193 xref: EMBL:BC011687 xref: EMBL:BC017290 xref: HGNC:HGNC:25997 xref: UniGene:Hs.445036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061992 ! IN80D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018281 name: INO80E_human def: "INO80 complex subunit E gene" [UniProtKB:Q8NBZ0] synonym: "CCDC95" EXACT [UniProtKB:Q8NBZ0] xref: EMBL:AK075133 xref: EMBL:BC047712 xref: HGNC:HGNC:26905 xref: UniGene:Hs.434864 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061989 ! IN80E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018282 name: INADL_human def: "InaD-like protein gene" [UniProtKB:Q8NI35] synonym: "PATJ" EXACT [UniProtKB:Q8NI35] xref: EMBL:AB044807 xref: EMBL:AC097064 xref: EMBL:AF397170 xref: EMBL:AJ001306 xref: EMBL:AJ224747 xref: EMBL:AJ224748 xref: EMBL:AL136458 xref: EMBL:AL353802 xref: EMBL:AL449143 xref: EMBL:AL590374 xref: EMBL:BC021135 xref: HGNC:HGNC:28881 xref: UniGene:Hs.478125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057881 ! INADL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018283 name: IFNAR1_human def: "Interferon-alpha/beta receptor alpha chain precursor gene" [UniProtKB:P17181] synonym: "IFNAR" EXACT [UniProtKB:P17181] xref: EMBL:AK222770 xref: EMBL:AK222812 xref: EMBL:AY654286 xref: EMBL:BC002590 xref: EMBL:BC021825 xref: EMBL:J03171 xref: EMBL:X60459 xref: HGNC:HGNC:5432 xref: UniGene:Hs.529400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055085 ! INAR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018284 name: IFNAR2_human def: "Interferon-alpha/beta receptor beta chain precursor gene" [UniProtKB:P48551] synonym: "IFNABR" EXACT [UniProtKB:P48551] synonym: "IFNARB" EXACT [UniProtKB:P48551] xref: EMBL:AY740397 xref: EMBL:L41942 xref: EMBL:L41943 xref: EMBL:L41944 xref: EMBL:L42238 xref: EMBL:L42239 xref: EMBL:L42240 xref: EMBL:L42241 xref: EMBL:L42242 xref: EMBL:L42243 xref: EMBL:L42323 xref: EMBL:U29584 xref: EMBL:X77722 xref: EMBL:X89772 xref: HGNC:HGNC:5433 xref: UniGene:Hs.701988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055406 ! INAR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018285 name: IFNGR1_human def: "Interferon-gamma receptor alpha chain precursor gene" [UniProtKB:P15260] xref: EMBL:AL050337 xref: EMBL:AY594694 xref: EMBL:BC005333 xref: EMBL:J03143 xref: HGNC:HGNC:5439 xref: UniGene:Hs.520414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055033 ! INGR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018286 name: IFNGR2_human def: "Interferon-gamma receptor beta chain precursor gene" [UniProtKB:P38484] synonym: "IFNGT1" EXACT [UniProtKB:P38484] xref: EMBL:AY644470 xref: EMBL:BC003624 xref: EMBL:U05875 xref: EMBL:U05877 xref: EMBL:U68755 xref: HGNC:HGNC:5440 xref: UniGene:Hs.634632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055319 ! INGR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018287 name: INO80_human def: "Putative DNA helicase INO80 complex homolog 1 gene" [UniProtKB:Q9ULG1] synonym: "INOC1" EXACT [UniProtKB:Q9ULG1] synonym: "KIAA1259" EXACT [UniProtKB:Q9ULG1] xref: EMBL:AB033085 xref: EMBL:AL137280 xref: HGNC:HGNC:26956 xref: UniGene:Hs.292949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061991 ! INO80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018288 name: INPP4A_human def: "Type I inositol-3,4-bisphosphate 4-phosphatase gene" [UniProtKB:Q96PE3] xref: EMBL:AC010134 xref: EMBL:AF368319 xref: EMBL:BC028361 xref: EMBL:U26398 xref: EMBL:U96919 xref: HGNC:HGNC:6074 xref: UniGene:Hs.580527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058331 ! INP4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018289 name: INPP4B_human def: "Type II inositol-3,4-bisphosphate 4-phosphatase gene" [UniProtKB:O15327] xref: EMBL:BC017924 xref: EMBL:BC072447 xref: EMBL:U96922 xref: HGNC:HGNC:6075 xref: UniGene:Hs.658245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054429 ! INP4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018290 name: INSIG1_human def: "Insulin-induced gene 1 protein gene" [UniProtKB:O15503] xref: EMBL:AY112745 xref: EMBL:BC001880 xref: EMBL:BT007227 xref: EMBL:CH236962 xref: EMBL:U96876 xref: HGNC:HGNC:6083 xref: UniGene:Hs.520819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054440 ! INSI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018291 name: INSL4_human def: "Early placenta insulin-like peptide precursor gene" [UniProtKB:Q14641] xref: EMBL:AL133547 xref: EMBL:BC026254 xref: EMBL:L34838 xref: HGNC:HGNC:6087 xref: UniGene:Hs.418506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056006 ! INSL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018292 name: INSM1_human def: "Insulinoma-associated protein 1 gene" [UniProtKB:Q01101] synonym: "IA1" EXACT [UniProtKB:Q01101] xref: EMBL:AL161658 xref: EMBL:M93119 xref: EMBL:U07172 xref: HGNC:HGNC:6090 xref: UniGene:Hs.89584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055685 ! INSM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018293 name: INSM2_human def: "Insulinoma-associated protein 2 gene" [UniProtKB:Q96T92] synonym: "IA6" EXACT [UniProtKB:Q96T92] synonym: "Nbla106" EXACT [UniProtKB:Q96T92] xref: EMBL:AB037912 xref: EMBL:AF260323 xref: EMBL:AK096639 xref: EMBL:BC130377 xref: EMBL:BC130379 xref: EMBL:CH471078 xref: HGNC:HGNC:17539 xref: UniGene:Hs.62813 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058404 ! INSM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018294 name: INSRR_human def: "Insulin receptor-related protein precursor gene" [UniProtKB:P14616] synonym: "IRR" EXACT [UniProtKB:P14616] xref: EMBL:AF064078 xref: EMBL:AL158169 xref: EMBL:CH471121 xref: EMBL:J05046 xref: HGNC:HGNC:6093 xref: UniGene:Hs.248138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029069 ! INSRR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018295 name: INS_human def: "Insulin precursor gene" [UniProtKB:P01308] xref: EMBL:AJ009655 xref: EMBL:AY138590 xref: EMBL:AY899304 xref: EMBL:BC005255 xref: EMBL:BT006808 xref: EMBL:CH471158 xref: EMBL:J00265 xref: EMBL:L15440 xref: EMBL:M10039 xref: EMBL:V00565 xref: EMBL:X70508 xref: HGNC:HGNC:6081 xref: UniGene:Hs.654579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054852 ! INS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018296 name: INVS_human def: "Inversin gene" [UniProtKB:Q9Y283] synonym: "INV" EXACT [UniProtKB:Q9Y283] synonym: "NPHP2" EXACT [UniProtKB:Q9Y283] xref: EMBL:AF039217 xref: EMBL:AF084367 xref: EMBL:AF084368 xref: EMBL:AF084369 xref: EMBL:AF084370 xref: EMBL:AF084371 xref: EMBL:AF084372 xref: EMBL:AF084373 xref: EMBL:AF084374 xref: EMBL:AF084375 xref: EMBL:AF084376 xref: EMBL:AF084377 xref: EMBL:AF084378 xref: EMBL:AF084379 xref: EMBL:AF084380 xref: EMBL:AF084381 xref: EMBL:AF084382 xref: EMBL:AL137072 xref: EMBL:AL356798 xref: EMBL:AL445214 xref: EMBL:BC006370 xref: EMBL:BC041665 xref: HGNC:HGNC:17870 xref: UniGene:Hs.558477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059298 ! INVS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018297 name: DIO2_human def: "Type II iodothyronine deiodinase gene" [UniProtKB:Q92813] synonym: "ITDI2" EXACT [UniProtKB:Q92813] synonym: "TXDI2" EXACT [UniProtKB:Q92813] xref: EMBL:AB041843 xref: EMBL:AC007372 xref: EMBL:AF093774 xref: EMBL:AL049837 xref: EMBL:BC074882 xref: EMBL:U53506 xref: HGNC:HGNC:2884 xref: UniGene:Hs.202354 xref: UniGene:Hs.694871 xref: UniGene:Hs.703089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058097 ! IOD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018298 name: ITPKA_human def: "Inositol-trisphosphate 3-kinase A gene" [UniProtKB:P23677] xref: EMBL:BC026331 xref: EMBL:X54938 xref: HGNC:HGNC:6178 xref: UniGene:Hs.2722 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055161 ! IP3KA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018299 name: IHPK2_human def: "Inositol hexakisphosphate kinase 2 gene" [UniProtKB:Q9UHH9] synonym: "IP6K2" EXACT [UniProtKB:Q9UHH9] synonym: "TCCCIA00113" EXACT [UniProtKB:Q9UHH9] xref: EMBL:AF177145 xref: EMBL:AL117458 xref: EMBL:AL137514 xref: EMBL:AY007091 xref: EMBL:BC001864 xref: EMBL:BC004469 xref: EMBL:BC019694 xref: EMBL:BC065533 xref: HGNC:HGNC:17313 xref: UniGene:Hs.595983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059140 ! IP6K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018300 name: PPP1R2P1_human def: "Putative protein phosphatase inhibitor 2-like protein 1 gene" [UniProtKB:Q96PQ5] xref: EMBL:AF275684 xref: HGNC:HGNC:9289 xref: UniGene:Hs.654585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058341 ! IPP2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018301 name: PPP1R2P3_human def: "Putative protein phosphatase inhibitor 2-like protein 3 gene" [UniProtKB:Q6NXS1] xref: EMBL:BC066922 xref: HGNC:HGNC:16318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056868 ! IPP2M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018302 name: PPP1R2_human def: "Protein phosphatase inhibitor 2 gene" [UniProtKB:P41236] synonym: "IPP2" EXACT [UniProtKB:P41236] xref: EMBL:AJ133812 xref: EMBL:AY063767 xref: EMBL:BC007655 xref: EMBL:BC066921 xref: EMBL:U68106 xref: EMBL:U68107 xref: EMBL:U68108 xref: EMBL:U68109 xref: EMBL:U68110 xref: EMBL:U68111 xref: EMBL:X78873 xref: EMBL:Z29646 xref: HGNC:HGNC:9288 xref: UniGene:Hs.535731 xref: UniGene:Hs.645626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055339 ! IPP2_HUMAN relationship: codes_for CCO:B0056869 ! Q6NXS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018303 name: PPP1R2P9_human def: "Putative type-1 protein phosphatase inhibitor 4 gene" [UniProtKB:O14990] xref: EMBL:AB044137 xref: EMBL:BC056673 xref: EMBL:Z94277 xref: HGNC:HGNC:16324 xref: UniGene:Hs.127689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054396 ! IPP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018304 name: IQCB1_human def: "IQ calmodulin-binding motif-containing protein 1 gene" [UniProtKB:Q15051] synonym: "KIAA0036" EXACT [UniProtKB:Q15051] synonym: "NPHP5" EXACT [UniProtKB:Q15051] synonym: "OK/SW-cl.85" EXACT [UniProtKB:Q15051] xref: EMBL:AB062481 xref: EMBL:AY714228 xref: EMBL:BC005806 xref: EMBL:D25278 xref: HGNC:HGNC:28949 xref: UniGene:Hs.604110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056038 ! IQCB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018305 name: IQSEC1_human def: "IQ motif and SEC7 domain-containing protein 1 gene" [UniProtKB:Q6DN90] synonym: "ARFGEP100" EXACT [UniProtKB:Q6DN90] synonym: "BRAG2" EXACT [UniProtKB:Q6DN90] synonym: "KIAA0763" EXACT [UniProtKB:Q6DN90] xref: EMBL:AB018306 xref: EMBL:AY653734 xref: EMBL:BC010267 xref: HGNC:HGNC:29112 xref: UniGene:Hs.705421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056728 ! IQEC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018306 name: IQSEC2_human def: "IQ motif and SEC7 domain-containing protein 2 gene" [UniProtKB:Q5JU85] synonym: "KIAA0522" EXACT [UniProtKB:Q5JU85] xref: EMBL:AB011094 xref: EMBL:AL139396 xref: EMBL:AL161779 xref: HGNC:HGNC:29059 xref: UniGene:Hs.496138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056485 ! IQEC2_HUMAN relationship: codes_for CCO:B0056491 ! Q5JUX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018307 name: IQSEC3_human def: "IQ motif and SEC7 domain-containing protein 3 gene" [UniProtKB:Q9UPP2] synonym: "KIAA1110" EXACT [UniProtKB:Q9UPP2] xref: EMBL:AB029033 xref: EMBL:AC007406 xref: EMBL:AC026369 xref: EMBL:AK091953 xref: EMBL:BC024764 xref: EMBL:BC042067 xref: HGNC:HGNC:29193 xref: UniGene:Hs.536319 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053860 ! A6NIF2_HUMAN relationship: codes_for CCO:B0059262 ! IQEC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018308 name: IRAK1_human def: "Interleukin-1 receptor-associated kinase 1 gene" [UniProtKB:P51617] synonym: "IRAK" EXACT [UniProtKB:P51617] xref: EMBL:AF030876 xref: EMBL:AF346607 xref: EMBL:BC014963 xref: EMBL:BC054000 xref: EMBL:DQ054788 xref: EMBL:L76191 xref: EMBL:U52112 xref: HGNC:HGNC:6112 xref: UniGene:Hs.522819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054008 ! A8MSL1_HUMAN relationship: codes_for CCO:B0055471 ! IRAK1_HUMAN relationship: codes_for CCO:B0058174 ! Q96C06_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018309 name: IRAK2_human def: "Interleukin-1 receptor-associated kinase-like 2 gene" [UniProtKB:O43187] xref: EMBL:AF026273 xref: EMBL:AJ496794 xref: EMBL:BC125184 xref: HGNC:HGNC:6113 xref: UniGene:Hs.449207 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054457 ! IRAK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018310 name: IRAK3_human def: "Interleukin-1 receptor-associated kinase 3 gene" [UniProtKB:Q9Y616] xref: EMBL:AF113136 xref: EMBL:BC057800 xref: EMBL:BC069388 xref: HGNC:HGNC:17020 xref: UniGene:Hs.369265 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059396 ! IRAK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018311 name: IRAK4_human def: "Interleukin-1 receptor-associated kinase 4 gene" [UniProtKB:Q9NWZ3] xref: EMBL:AF155118 xref: EMBL:AF445802 xref: EMBL:AK000528 xref: EMBL:AY186092 xref: EMBL:BC013316 xref: HGNC:HGNC:17967 xref: UniGene:Hs.138499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058944 ! IRAK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018312 name: IRF2_human def: "Interferon regulatory factor 2 gene" [UniProtKB:P14316] xref: EMBL:BC015803 xref: EMBL:X15949 xref: HGNC:HGNC:6117 xref: UniGene:Hs.654566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055022 ! IRF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018313 name: IRF3_human def: "Interferon regulatory factor 3 gene" [UniProtKB:Q14653] xref: EMBL:AB102884 xref: EMBL:BC009395 xref: EMBL:BC071721 xref: EMBL:CH471177 xref: EMBL:U86636 xref: EMBL:Z56281 xref: HGNC:HGNC:6118 xref: UniGene:Hs.289052 xref: UniGene:Hs.75254 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056009 ! IRF3_HUMAN relationship: codes_for CCO:B0056426 ! Q5FBY4_HUMAN relationship: codes_for CCO:B0058218 ! Q96GL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018314 name: IRF4_human def: "Interferon regulatory factor 4 gene" [UniProtKB:Q15306] synonym: "MUM1" EXACT [UniProtKB:Q15306] xref: EMBL:AL365272 xref: EMBL:AL589962 xref: EMBL:BC015752 xref: EMBL:U52682 xref: EMBL:U63738 xref: HGNC:HGNC:6119 xref: UniGene:Hs.401013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056056 ! IRF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018315 name: KCNJ11_human def: "ATP-sensitive inward rectifier potassium channel 11 gene" [UniProtKB:Q14654] xref: EMBL:BC064497 xref: EMBL:BC112358 xref: EMBL:D50582 xref: HGNC:HGNC:6257 xref: UniGene:Hs.248141 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030971 ! IRK11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018316 name: IL1RAPL1_human def: "X-linked interleukin-1 receptor accessory protein-like 1 precursor gene" [UniProtKB:Q9NZN1] synonym: "OPHN4" EXACT [UniProtKB:Q9NZN1] xref: EMBL:AB102650 xref: EMBL:AC005748 xref: EMBL:AC121343 xref: EMBL:AC129852 xref: EMBL:AF181284 xref: EMBL:AF284435 xref: EMBL:AJ243874 xref: EMBL:AL031466 xref: EMBL:AL031575 xref: EMBL:BC126345 xref: EMBL:BC126347 xref: EMBL:CH471074 xref: HGNC:HGNC:5996 xref: UniGene:Hs.658912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053698 ! A0AVG4_HUMAN relationship: codes_for CCO:B0059005 ! IRPL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018317 name: IL1RAPL2_human def: "X-linked interleukin-1 receptor accessory protein-like 2 precursor gene" [UniProtKB:Q9NP60] synonym: "IL1R9" EXACT [UniProtKB:Q9NP60] xref: EMBL:AF181285 xref: EMBL:AF212016 xref: EMBL:AF284436 xref: EMBL:AJ272208 xref: EMBL:AJ290436 xref: EMBL:AK290196 xref: EMBL:AL050401 xref: EMBL:BC104784 xref: EMBL:BC104786 xref: EMBL:Z68328 xref: EMBL:Z68330 xref: EMBL:Z68908 xref: EMBL:Z69721 xref: EMBL:Z74477 xref: EMBL:Z74619 xref: EMBL:Z81144 xref: HGNC:HGNC:5997 xref: UniGene:Hs.675519 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056212 ! Q2M3U3_HUMAN relationship: codes_for CCO:B0058832 ! IRPL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018318 name: IRX1_human def: "Iroquois-class homeodomain protein IRX-1 gene" [UniProtKB:P78414] synonym: "IRXA1" EXACT [UniProtKB:P78414] xref: EMBL:AY335938 xref: EMBL:AY335947 xref: EMBL:BC029160 xref: EMBL:U90307 xref: HGNC:HGNC:14358 xref: UniGene:Hs.424156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031071 ! IRX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018319 name: IRX2_human def: "Iroquois-class homeodomain protein IRX-2 gene" [UniProtKB:Q9BZI1] synonym: "IRXA2" EXACT [UniProtKB:Q9BZI1] xref: EMBL:AF319967 xref: EMBL:AY335939 xref: EMBL:AY335940 xref: EMBL:BC065189 xref: HGNC:HGNC:14359 xref: UniGene:Hs.282089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031069 ! IRX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018320 name: IRX3_human def: "Iroquois-class homeodomain protein IRX-3 gene" [UniProtKB:P78415] synonym: "IRXB1" EXACT [UniProtKB:P78415] xref: EMBL:AY335942 xref: EMBL:AY335943 xref: EMBL:BC023667 xref: EMBL:U90308 xref: HGNC:HGNC:14360 xref: UniGene:Hs.499205 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031070 ! IRX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018321 name: IRX4_human def: "Iroquois-class homeodomain protein IRX-4 gene" [UniProtKB:P78413] synonym: "IRXA3" EXACT [UniProtKB:P78413] xref: EMBL:AF124733 xref: EMBL:AY335941 xref: EMBL:U90306 xref: HGNC:HGNC:6129 xref: UniGene:Hs.196927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055644 ! IRX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018322 name: IRX5_human def: "Iroquois-class homeodomain protein IRX-5 gene" [UniProtKB:P78411] synonym: "IRX2A" EXACT [UniProtKB:P78411] synonym: "IRXB2" EXACT [UniProtKB:P78411] xref: EMBL:AY335944 xref: EMBL:AY335945 xref: EMBL:U90304 xref: EMBL:U90309 xref: HGNC:HGNC:14361 xref: UniGene:Hs.435730 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031067 ! IRX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018323 name: IRX6_human def: "Iroquois-class homeodomain protein IRX-6 gene" [UniProtKB:P78412] synonym: "IRX7" EXACT [UniProtKB:P78412] synonym: "IRXB3" EXACT [UniProtKB:P78412] xref: EMBL:AK125053 xref: EMBL:AY335937 xref: EMBL:AY335946 xref: EMBL:U90305 xref: HGNC:HGNC:14675 xref: UniGene:Hs.369907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055643 ! IRX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018324 name: ISG20_human def: "Interferon-stimulated gene 20 kDa protein gene" [UniProtKB:Q96AZ6] synonym: "HEM45" EXACT [UniProtKB:Q96AZ6] xref: EMBL:BC007922 xref: EMBL:BC016341 xref: EMBL:BT006952 xref: EMBL:CR456942 xref: EMBL:U88964 xref: EMBL:X89773 xref: HGNC:HGNC:6130 xref: UniGene:Hs.459265 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058159 ! ISG20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018325 name: SPINK5_human def: "Serine protease inhibitor Kazal-type 5 precursor gene" [UniProtKB:Q9NQ38] xref: EMBL:AC008722 xref: EMBL:AF295783 xref: EMBL:AF295784 xref: EMBL:AJ228139 xref: EMBL:AJ270944 xref: EMBL:AJ276577 xref: EMBL:AJ276578 xref: EMBL:AJ276579 xref: EMBL:AJ276580 xref: EMBL:AJ391230 xref: EMBL:AJ391231 xref: EMBL:AJ391232 xref: EMBL:AJ391233 xref: EMBL:AJ391234 xref: EMBL:AJ391235 xref: EMBL:AJ391236 xref: EMBL:AJ391237 xref: EMBL:AJ391238 xref: EMBL:AJ391239 xref: EMBL:AJ391240 xref: EMBL:AJ391241 xref: EMBL:AJ391242 xref: EMBL:AJ391243 xref: EMBL:AJ391244 xref: EMBL:AJ391245 xref: EMBL:AJ391246 xref: EMBL:AJ391247 xref: EMBL:AJ391248 xref: EMBL:AJ391249 xref: EMBL:AJ391250 xref: EMBL:AJ391251 xref: EMBL:AJ391252 xref: EMBL:AJ391253 xref: EMBL:AJ391254 xref: HGNC:HGNC:15464 xref: UniGene:Hs.331555 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058862 ! ISK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018326 name: ISL1_human def: "Insulin gene enhancer protein ISL-1 gene" [UniProtKB:P61371] xref: EMBL:BC031213 xref: EMBL:S70721 xref: EMBL:U07559 xref: HGNC:HGNC:6132 xref: UniGene:Hs.505 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055610 ! ISL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018327 name: ISL2_human def: "Insulin gene enhancer protein ISL-2 gene" [UniProtKB:Q96A47] xref: EMBL:BC011967 xref: EMBL:BC012136 xref: HGNC:HGNC:18524 xref: UniGene:Hs.444677 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058146 ! ISL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018328 name: ISOC2_human def: "Isochorismatase domain-containing protein 2, mitochondrial precursor gene" [UniProtKB:Q96AB3] xref: EMBL:AK027122 xref: EMBL:BC017344 xref: EMBL:CR457377 xref: HGNC:HGNC:26278 xref: UniGene:Hs.467306 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058149 ! ISOC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018329 name: ISX_human def: "Intestine-specific homeobox gene" [UniProtKB:Q2M1V0] synonym: "RAXLX" EXACT [UniProtKB:Q2M1V0] xref: EMBL:AL024494 xref: EMBL:BC112212 xref: EMBL:BC113633 xref: EMBL:CR749372 xref: EMBL:Z83853 xref: HGNC:HGNC:28084 xref: UniGene:Hs.567637 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056206 ! ISX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018330 name: ITGA10_human def: "Integrin alpha-10 precursor gene" [UniProtKB:O75578] synonym: "UNQ468/PRO827" EXACT [UniProtKB:O75578] xref: EMBL:AF074015 xref: EMBL:AF112345 xref: EMBL:AF172723 xref: EMBL:AY358325 xref: HGNC:HGNC:6135 xref: UniGene:Hs.158237 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054652 ! ITA10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018331 name: ITGA1_human def: "Integrin alpha-1 precursor gene" [UniProtKB:P56199] xref: EMBL:AC022133 xref: EMBL:AC025180 xref: EMBL:AC027326 xref: EMBL:X68742 xref: HGNC:HGNC:6134 xref: UniGene:Hs.696076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055541 ! ITA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018332 name: ITGA2B_human def: "Integrin alpha-IIb precursor gene" [UniProtKB:P08514] synonym: "GP2B" EXACT [UniProtKB:P08514] synonym: "ITGAB" EXACT [UniProtKB:P08514] xref: EMBL:AF098114 xref: EMBL:BC117443 xref: EMBL:BC126442 xref: EMBL:J02764 xref: EMBL:M18085 xref: EMBL:M22568 xref: EMBL:M22569 xref: EMBL:M33319 xref: EMBL:M33320 xref: EMBL:M34344 xref: EMBL:M34480 xref: EMBL:M54799 xref: EMBL:X06831 xref: HGNC:HGNC:6138 xref: UniGene:Hs.411312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026215 ! ITA2B_HUMAN relationship: codes_for CCO:B0026216 ! Q17R67_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018333 name: ITGA3_human def: "Integrin alpha-3 precursor gene" [UniProtKB:P26006] synonym: "MSK18" EXACT [UniProtKB:P26006] xref: EMBL:AK289961 xref: EMBL:BC150190 xref: EMBL:CH471109 xref: EMBL:D01038 xref: EMBL:M59911 xref: HGNC:HGNC:6139 xref: UniGene:Hs.265829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055189 ! ITA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018334 name: ITGA4_human def: "Integrin alpha-4 precursor gene" [UniProtKB:P13612] synonym: "CD49D" EXACT [UniProtKB:P13612] xref: EMBL:AC020595 xref: EMBL:L12002 xref: EMBL:X16983 xref: HGNC:HGNC:6140 xref: UniGene:Hs.694732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055015 ! ITA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018335 name: ITGA5_human def: "Integrin alpha-5 precursor gene" [UniProtKB:P08648] synonym: "FNRA" EXACT [UniProtKB:P08648] xref: EMBL:BC008786 xref: EMBL:M13918 xref: EMBL:X06256 xref: HGNC:HGNC:6141 xref: UniGene:Hs.505654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026217 ! ITA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018336 name: ITGA6_human def: "Integrin alpha-6 precursor gene" [UniProtKB:P23229] xref: EMBL:AF166335 xref: EMBL:AF166336 xref: EMBL:AF166337 xref: EMBL:AF166338 xref: EMBL:AF166339 xref: EMBL:AF166340 xref: EMBL:AF166341 xref: EMBL:AF166342 xref: EMBL:AF166343 xref: EMBL:L40385 xref: EMBL:S52135 xref: EMBL:S66196 xref: EMBL:S66213 xref: EMBL:X53586 xref: EMBL:X59512 xref: HGNC:HGNC:6142 xref: UniGene:Hs.133397 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055154 ! ITA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018337 name: ITGA7_human def: "Integrin alpha-7 precursor gene" [UniProtKB:Q13683] synonym: "UNQ406/PRO768" EXACT [UniProtKB:Q13683] xref: EMBL:AF032108 xref: EMBL:AF034833 xref: EMBL:AF052050 xref: EMBL:AF072132 xref: EMBL:AJ228836 xref: EMBL:AJ228837 xref: EMBL:AJ228838 xref: EMBL:AJ228839 xref: EMBL:AJ228840 xref: EMBL:AJ228841 xref: EMBL:AJ228842 xref: EMBL:AJ228843 xref: EMBL:AJ228844 xref: EMBL:AJ228845 xref: EMBL:AJ228846 xref: EMBL:AJ228847 xref: EMBL:AJ228848 xref: EMBL:AJ228849 xref: EMBL:AJ228850 xref: EMBL:AJ228851 xref: EMBL:AJ228852 xref: EMBL:AJ228853 xref: EMBL:AJ228854 xref: EMBL:AJ228855 xref: EMBL:AJ228856 xref: EMBL:AJ228857 xref: EMBL:AJ228858 xref: EMBL:AJ228859 xref: EMBL:AJ228860 xref: EMBL:AJ228862 xref: EMBL:AY358882 xref: EMBL:X74295 xref: HGNC:HGNC:6143 xref: UniGene:Hs.524484 xref: UniGene:Hs.639559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055939 ! ITA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018338 name: ITGA8_human def: "Integrin alpha-8 precursor gene" [UniProtKB:P53708] xref: EMBL:AL359645 xref: EMBL:AL590636 xref: EMBL:AY371697 xref: EMBL:L36531 xref: HGNC:HGNC:6144 xref: UniGene:Hs.171311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026213 ! ITA8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018339 name: ITGA9_human def: "Integrin alpha-9 precursor gene" [UniProtKB:Q13797] xref: EMBL:D25303 xref: EMBL:L24158 xref: HGNC:HGNC:6145 xref: UniGene:Hs.113157 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055943 ! ITA9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018340 name: ITGAV_human def: "Integrin alpha-V precursor gene" [UniProtKB:P06756] synonym: "MSK8" EXACT [UniProtKB:P06756] synonym: "VNRA" EXACT [UniProtKB:P06756] xref: EMBL:AB209894 xref: EMBL:AC017101 xref: EMBL:AF251818 xref: EMBL:AF251819 xref: EMBL:AF251820 xref: EMBL:AF251821 xref: EMBL:AF251822 xref: EMBL:AF251823 xref: EMBL:AF251824 xref: EMBL:AF251825 xref: EMBL:AF251826 xref: EMBL:AF251827 xref: EMBL:AF251828 xref: EMBL:AF251829 xref: EMBL:AF251830 xref: EMBL:AF251831 xref: EMBL:AF251832 xref: EMBL:AF251833 xref: EMBL:AF251834 xref: EMBL:AF251835 xref: EMBL:AF251836 xref: EMBL:AF251837 xref: EMBL:AF251838 xref: EMBL:AF251839 xref: EMBL:AF251840 xref: EMBL:AF251841 xref: EMBL:BC126231 xref: EMBL:M14648 xref: EMBL:U07375 xref: HGNC:HGNC:6150 xref: UniGene:Hs.436873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026218 ! ITAV_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018341 name: ITGB1BP1_human def: "Integrin beta-1-binding protein 1 gene" [UniProtKB:O14713] synonym: "ICAP1" EXACT [UniProtKB:O14713] xref: EMBL:AC080162 xref: EMBL:AF012023 xref: EMBL:AF012024 xref: EMBL:BC012264 xref: EMBL:CH471053 xref: HGNC:HGNC:23927 xref: UniGene:Hs.467662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053990 ! A8MPU2_HUMAN relationship: codes_for CCO:B0054370 ! ITBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018342 name: ITGB1BP2_human def: "Integrin beta-1-binding protein 2 gene" [UniProtKB:Q9UKP3] synonym: "MSTP015" EXACT [UniProtKB:Q9UKP3] xref: EMBL:AF110225 xref: EMBL:AF140690 xref: HGNC:HGNC:6154 xref: UniGene:Hs.109999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059198 ! ITBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018343 name: ITCH_human def: "E3 ubiquitin-protein ligase Itchy homolog gene" [UniProtKB:Q96J02] xref: EMBL:AB056663 xref: EMBL:AF038564 xref: EMBL:AF095745 xref: EMBL:AL109923 xref: EMBL:AL356299 xref: EMBL:BC006848 xref: EMBL:BC011571 xref: EMBL:CH471077 xref: HGNC:HGNC:13890 xref: UniGene:Hs.632272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058235 ! ITCH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018344 name: ITGBL1_human def: "Integrin beta-like protein 1 precursor gene" [UniProtKB:O95965] synonym: "OSCP" EXACT [UniProtKB:O95965] synonym: "TIED" EXACT [UniProtKB:O95965] xref: EMBL:AE014302 xref: EMBL:AF072752 xref: EMBL:AK291340 xref: EMBL:AL139800 xref: EMBL:AL160153 xref: EMBL:AL355807 xref: EMBL:AL359052 xref: EMBL:BC036788 xref: EMBL:CH471085 xref: HGNC:HGNC:6164 xref: UniGene:Hs.696554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054809 ! ITGBL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018345 name: ITK_human def: "Tyrosine-protein kinase ITK/TSK gene" [UniProtKB:Q08881] synonym: "EMT" EXACT [UniProtKB:Q08881] synonym: "LYK" EXACT [UniProtKB:Q08881] xref: EMBL:BC109077 xref: EMBL:BC109078 xref: EMBL:D13720 xref: EMBL:L10717 xref: EMBL:S65186 xref: HGNC:HGNC:6171 xref: UniGene:Hs.558348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055796 ! ITK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018346 name: ITLN1_human def: "Intelectin-1 precursor gene" [UniProtKB:Q8WWA0] synonym: "INTL" EXACT [UniProtKB:Q8WWA0] synonym: "ITLN" EXACT [UniProtKB:Q8WWA0] synonym: "LFR" EXACT [UniProtKB:Q8WWA0] synonym: "UNQ640/PRO1270" EXACT [UniProtKB:Q8WWA0] xref: EMBL:AB036706 xref: EMBL:AF271386 xref: EMBL:AK000029 xref: EMBL:AY065972 xref: EMBL:AY157361 xref: EMBL:AY157362 xref: EMBL:AY358359 xref: EMBL:AY549722 xref: EMBL:BC020664 xref: EMBL:CR457224 xref: HGNC:HGNC:18259 xref: UniGene:Hs.50813 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058002 ! ITLN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018347 name: ITLN2_human def: "Intelectin-2 precursor gene" [UniProtKB:Q8WWU7] synonym: "UNQ2789/PRO7179" EXACT [UniProtKB:Q8WWU7] xref: EMBL:AY065973 xref: EMBL:AY358905 xref: EMBL:BC117225 xref: HGNC:HGNC:20599 xref: UniGene:Hs.385631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056186 ! Q17RR2_HUMAN relationship: codes_for CCO:B0058006 ! ITLN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018348 name: ITPK1_human def: "Inositol-tetrakisphosphate 1-kinase gene" [UniProtKB:Q13572] xref: EMBL:AF279372 xref: EMBL:BC003622 xref: EMBL:BC007428 xref: EMBL:BC018192 xref: EMBL:U51336 xref: HGNC:HGNC:6177 xref: UniGene:Hs.308122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055931 ! ITPK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018349 name: ITPR1_human def: "Inositol 1,4,5-trisphosphate receptor type 1 gene" [UniProtKB:Q14643] synonym: "INSP3R1" EXACT [UniProtKB:Q14643] xref: EMBL:D26070 xref: EMBL:L38019 xref: EMBL:S82269 xref: EMBL:U23850 xref: HGNC:HGNC:6180 xref: UniGene:Hs.567295 xref: UniGene:Hs.699169 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056007 ! ITPR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018350 name: ITPR2_human def: "Inositol 1,4,5-trisphosphate receptor type 2 gene" [UniProtKB:Q14571] xref: EMBL:AB012610 xref: EMBL:D26350 xref: HGNC:HGNC:6181 xref: UniGene:Hs.512235 xref: UniGene:Hs.659892 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055994 ! ITPR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018351 name: ITPR3_human def: "Inositol 1,4,5-trisphosphate receptor type 3 gene" [UniProtKB:Q14573] xref: EMBL:AL139044 xref: EMBL:CH471081 xref: EMBL:D26351 xref: EMBL:U01062 xref: HGNC:HGNC:6182 xref: UniGene:Hs.65758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055995 ! ITPR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018352 name: JARID1A_human def: "Histone demethylase JARID1A gene" [UniProtKB:P29375] synonym: "RBBP2" EXACT [UniProtKB:P29375] synonym: "RBP2" EXACT [UniProtKB:P29375] xref: EMBL:AB209999 xref: EMBL:AC005844 xref: EMBL:AC007406 xref: EMBL:BC048307 xref: EMBL:BC053893 xref: EMBL:BC110916 xref: EMBL:S66431 xref: HGNC:HGNC:9886 xref: UniGene:Hs.654806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055213 ! JAD1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018353 name: JARID1B_human def: "Histone demethylase JARID1B gene" [UniProtKB:Q9UGL1] synonym: "PLU1" EXACT [UniProtKB:Q9UGL1] synonym: "RBBP2H1" EXACT [UniProtKB:Q9UGL1] xref: EMBL:AF087481 xref: EMBL:AJ132440 xref: EMBL:AJ243706 xref: HGNC:HGNC:18039 xref: UniGene:Hs.443650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059124 ! JAD1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018354 name: JARID1C_human def: "Histone demethylase JARID1C gene" [UniProtKB:P41229] synonym: "DXS1272E" EXACT [UniProtKB:P41229] synonym: "SMCX" EXACT [UniProtKB:P41229] synonym: "XE169" EXACT [UniProtKB:P41229] xref: EMBL:AL139396 xref: EMBL:BC054499 xref: EMBL:L25270 xref: EMBL:Z29650 xref: HGNC:HGNC:11114 xref: UniGene:Hs.631768 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055337 ! JAD1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018355 name: PHF17_human def: "Protein Jade-1 gene" [UniProtKB:Q6IE81] synonym: "JADE1" EXACT [UniProtKB:Q6IE81] synonym: "KIAA1807" EXACT [UniProtKB:Q6IE81] xref: EMBL:AB058710 xref: EMBL:AC093783 xref: EMBL:AC108024 xref: EMBL:AF520952 xref: EMBL:AK026132 xref: EMBL:AK027620 xref: EMBL:AK074986 xref: EMBL:AK127326 xref: EMBL:BC032376 xref: EMBL:BN000287 xref: HGNC:HGNC:30027 xref: UniGene:Hs.12420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056759 ! JADE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018356 name: JARID2_human def: "Protein Jumonji gene" [UniProtKB:Q92833] synonym: "JMJ" EXACT [UniProtKB:Q92833] xref: EMBL:AL021938 xref: EMBL:AL136162 xref: EMBL:BC046246 xref: EMBL:U57592 xref: HGNC:HGNC:6196 xref: UniGene:Hs.696068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058099 ! JARD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018357 name: JAZF1_human def: "Juxtaposed with another zinc finger protein 1 gene" [UniProtKB:Q86VZ6] synonym: "TIP27" EXACT [UniProtKB:Q86VZ6] synonym: "ZNF802" EXACT [UniProtKB:Q86VZ6] xref: EMBL:AL834234 xref: EMBL:AY372319 xref: EMBL:BC042441 xref: HGNC:HGNC:28917 xref: UniGene:Hs.368944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057269 ! JAZF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018358 name: JDP2_human def: "Jun dimerization protein 2 gene" [UniProtKB:Q8WYK2] xref: EMBL:AB077880 xref: EMBL:AC009363 xref: EMBL:AF111167 xref: EMBL:BC051303 xref: EMBL:CH471061 xref: HGNC:HGNC:17546 xref: UniGene:Hs.699420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058043 ! JDP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018359 name: JMJD1A_human def: "JmjC domain-containing histone demethylation protein 2A gene" [UniProtKB:Q9Y4C1] synonym: "JHDM2A" EXACT [UniProtKB:Q9Y4C1] synonym: "JMJD1" EXACT [UniProtKB:Q9Y4C1] synonym: "KIAA0742" EXACT [UniProtKB:Q9Y4C1] synonym: "TSGA" EXACT [UniProtKB:Q9Y4C1] xref: EMBL:AB018285 xref: EMBL:AC068288 xref: EMBL:AL832150 xref: EMBL:BX640698 xref: EMBL:CR749581 xref: HGNC:HGNC:20815 xref: UniGene:Hs.557425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059357 ! JHD2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018360 name: JMJD1B_human def: "JmjC domain-containing histone demethylation protein 2B gene" [UniProtKB:Q7LBC6] synonym: "C5orf7" EXACT [UniProtKB:Q7LBC6] synonym: "JHDM2B" EXACT [UniProtKB:Q7LBC6] synonym: "KIAA1082" EXACT [UniProtKB:Q7LBC6] xref: EMBL:AB029005 xref: EMBL:AF251039 xref: EMBL:AF338242 xref: EMBL:BC000539 xref: EMBL:BC001202 xref: HGNC:HGNC:1337 xref: UniGene:Hs.483486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057122 ! JHD2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018361 name: JMJD1C_human def: "Probable JmjC domain-containing histone demethylation protein 2C gene" [UniProtKB:Q15652] synonym: "JHDM2C" EXACT [UniProtKB:Q15652] synonym: "KIAA1380" EXACT [UniProtKB:Q15652] synonym: "TRIP8" EXACT [UniProtKB:Q15652] xref: EMBL:AB037801 xref: EMBL:AC022022 xref: EMBL:AK027280 xref: EMBL:AL590502 xref: EMBL:AL607128 xref: EMBL:AL713895 xref: EMBL:AL831917 xref: EMBL:BX537954 xref: EMBL:L40411 xref: HGNC:HGNC:12313 xref: UniGene:Hs.413416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056093 ! JHD2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018362 name: JMJD2A_human def: "JmjC domain-containing histone demethylation protein 3A gene" [UniProtKB:O75164] synonym: "JHDM3A" EXACT [UniProtKB:O75164] synonym: "JMJD2" EXACT [UniProtKB:O75164] synonym: "KIAA0677" EXACT [UniProtKB:O75164] xref: EMBL:AB014577 xref: EMBL:AC092815 xref: EMBL:AL451062 xref: EMBL:BC002558 xref: HGNC:HGNC:22978 xref: UniGene:Hs.155983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054610 ! JHD3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018363 name: JMJD2B_human def: "JmjC domain-containing histone demethylation protein 3B gene" [UniProtKB:O94953] synonym: "JHDM3B" EXACT [UniProtKB:O94953] synonym: "KIAA0876" EXACT [UniProtKB:O94953] xref: EMBL:AB020683 xref: EMBL:AC005595 xref: EMBL:AC022517 xref: EMBL:AL133622 xref: EMBL:BC063889 xref: HGNC:HGNC:29136 xref: UniGene:Hs.654816 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054713 ! JHD3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018364 name: JMJD2C_human def: "JmjC domain-containing histone demethylation protein 3C gene" [UniProtKB:Q9H3R0] synonym: "GASC1" EXACT [UniProtKB:Q9H3R0] synonym: "JHDM3C" EXACT [UniProtKB:Q9H3R0] synonym: "KIAA0780" EXACT [UniProtKB:Q9H3R0] xref: EMBL:AB018323 xref: EMBL:AB037901 xref: EMBL:AL137020 xref: EMBL:AL161443 xref: EMBL:AL354707 xref: EMBL:AL445592 xref: EMBL:AL513412 xref: EMBL:BC104859 xref: EMBL:BC104861 xref: HGNC:HGNC:17071 xref: UniGene:Hs.157106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058709 ! JHD3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018365 name: MAPK8IP1_human def: "C-jun-amino-terminal kinase-interacting protein 1 gene" [UniProtKB:Q9UQF2] synonym: "IB1" EXACT [UniProtKB:Q9UQF2] synonym: "JIP1" EXACT [UniProtKB:Q9UQF2] synonym: "PRKM8IP" EXACT [UniProtKB:Q9UQF2] xref: EMBL:AF007134 xref: EMBL:AF074091 xref: HGNC:HGNC:6882 xref: UniGene:Hs.234249 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059280 ! JIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018366 name: MAPK8IP2_human def: "C-jun-amino-terminal kinase-interacting protein 2 gene" [UniProtKB:Q13387] synonym: "IB2" EXACT [UniProtKB:Q13387] synonym: "JIP2" EXACT [UniProtKB:Q13387] synonym: "PRKM8IPL" EXACT [UniProtKB:Q13387] xref: EMBL:AF136382 xref: EMBL:AF218778 xref: EMBL:AL021708 xref: EMBL:BC009940 xref: EMBL:U62317 xref: EMBL:U79261 xref: HGNC:HGNC:6883 xref: UniGene:Hs.558180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055904 ! JIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018367 name: JMJD6_human def: "Histone arginine demethylase JMJD6 gene" [UniProtKB:Q6NYC1] synonym: "KIAA0585" EXACT [UniProtKB:Q6NYC1] synonym: "PTDSR" EXACT [UniProtKB:Q6NYC1] xref: EMBL:AB011157 xref: EMBL:AB073711 xref: EMBL:BC047003 xref: EMBL:BC066654 xref: HGNC:HGNC:19355 xref: UniGene:Hs.514505 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056871 ! JMJD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018368 name: JPH1_human def: "Junctophilin-1 gene" [UniProtKB:Q9HDC5] synonym: "JP1" EXACT [UniProtKB:Q9HDC5] xref: EMBL:AB042635 xref: EMBL:AF110324 xref: HGNC:HGNC:14201 xref: UniGene:Hs.657367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061985 ! JPH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018369 name: JUND_human def: "Transcription factor jun-D gene" [UniProtKB:P17535] xref: EMBL:X51346 xref: EMBL:X56681 xref: HGNC:HGNC:6206 xref: UniGene:Hs.2780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055089 ! JUND_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018370 name: KIAA1219_human def: "Protein KIAA1219 gene" [UniProtKB:Q86X10] xref: EMBL:AB033045 xref: EMBL:AK123576 xref: EMBL:AL035419 xref: EMBL:AL049868 xref: EMBL:AL132998 xref: EMBL:AL834436 xref: EMBL:BC010916 xref: EMBL:BC018668 xref: EMBL:BC047482 xref: HGNC:HGNC:29221 xref: UniGene:Hs.655758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057283 ! K1219_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018371 name: KIAA1688_human def: "Uncharacterized protein KIAA1688 gene" [UniProtKB:Q9C0H5] xref: EMBL:AB051475 xref: UniGene:Hs.148988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058620 ! K1688_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018372 name: KIAA2018_human def: "Basic helix-loop-helix domain-containing protein KIAA2018 gene" [UniProtKB:Q68DE3] xref: EMBL:AB095938 xref: EMBL:AC055740 xref: EMBL:AK023308 xref: EMBL:BX537728 xref: EMBL:CR749439 xref: HGNC:HGNC:30494 xref: UniGene:Hs.632570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056702 ! K2018_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018373 name: ZBTB33_human def: "Transcriptional regulator Kaiso gene" [UniProtKB:Q86T24] synonym: "KAISO" EXACT [UniProtKB:Q86T24] synonym: "ZNF348" EXACT [UniProtKB:Q86T24] xref: EMBL:AC002086 xref: EMBL:AL833604 xref: EMBL:AL833856 xref: EMBL:BC042753 xref: EMBL:BX538016 xref: EMBL:BX538101 xref: HGNC:HGNC:16682 xref: UniGene:Hs.143604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057236 ! KAISO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018374 name: KALRN_human def: "Kalirin gene" [UniProtKB:O60229] synonym: "DUET" EXACT [UniProtKB:O60229] synonym: "DUO" EXACT [UniProtKB:O60229] synonym: "HAPIP" EXACT [UniProtKB:O60229] synonym: "TRAD" EXACT [UniProtKB:O60229] xref: EMBL:AB011422 xref: EMBL:AC022336 xref: EMBL:AC069233 xref: EMBL:AC080008 xref: EMBL:AC112129 xref: EMBL:AC117401 xref: EMBL:AK125979 xref: EMBL:AK131379 xref: EMBL:AL137629 xref: EMBL:BC026865 xref: EMBL:BC058015 xref: EMBL:U94190 xref: HGNC:HGNC:4814 xref: UniGene:Hs.8004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054534 ! KALRN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018375 name: KAZALD1_human def: "Kazal-type serine protease inhibitor domain-containing protein 1 precursor gene" [UniProtKB:Q96I82] synonym: "FKSG28" EXACT [UniProtKB:Q96I82] synonym: "FKSG40" EXACT [UniProtKB:Q96I82] synonym: "UNQ2945/PRO21184" EXACT [UniProtKB:Q96I82] xref: EMBL:AF333487 xref: EMBL:AK172862 xref: EMBL:AL133215 xref: EMBL:AY014271 xref: EMBL:AY359087 xref: EMBL:BC007758 xref: HGNC:HGNC:25460 xref: UniGene:Hs.534859 xref: UniGene:Hs.632079 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058226 ! KAZD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018376 name: NKIRAS1_human def: "NF-kappa-B inhibitor-interacting Ras-like protein 1 gene" [UniProtKB:Q9NYS0] synonym: "KBRAS1" EXACT [UniProtKB:Q9NYS0] xref: EMBL:AF229839 xref: EMBL:AK027749 xref: EMBL:BC012145 xref: EMBL:BC066940 xref: EMBL:DQ314881 xref: HGNC:HGNC:17899 xref: UniGene:Hs.173202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058970 ! KBRS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018377 name: NKIRAS2_human def: "NF-kappa-B inhibitor-interacting Ras-like protein 2 gene" [UniProtKB:Q9NYR9] synonym: "KBRAS2" EXACT [UniProtKB:Q9NYR9] xref: EMBL:AC105024 xref: EMBL:AF229840 xref: EMBL:AK027265 xref: EMBL:AL137682 xref: EMBL:BC007450 xref: EMBL:BC063498 xref: EMBL:CH471152 xref: EMBL:DQ314882 xref: HGNC:HGNC:17898 xref: UniGene:Hs.632252 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054012 ! A8MST8_HUMAN relationship: codes_for CCO:B0058969 ! KBRS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018378 name: CSNK1A1L_human def: "Casein kinase I isoform alpha-like gene" [UniProtKB:Q8N752] xref: EMBL:AL391383 xref: EMBL:BC028723 xref: EMBL:CH471075 xref: HGNC:HGNC:20289 xref: UniGene:Hs.512897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057498 ! KC1AL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018379 name: CSNK1A1_human def: "Casein kinase I isoform alpha gene" [UniProtKB:P48729] xref: EMBL:BC008717 xref: EMBL:BT019829 xref: EMBL:BT019830 xref: EMBL:CH471062 xref: EMBL:CR542206 xref: EMBL:DQ082865 xref: EMBL:L37042 xref: EMBL:X80693 xref: HGNC:HGNC:2451 xref: UniGene:Hs.529862 xref: UniGene:Hs.699188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055410 ! KC1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018380 name: CSNK1G1_human def: "Casein kinase I isoform gamma-1 gene" [UniProtKB:Q9HCP0] xref: EMBL:AB042562 xref: EMBL:AB042563 xref: EMBL:BC017236 xref: HGNC:HGNC:2454 xref: UniGene:Hs.646508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020417 ! KC1G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018381 name: CSNK1G2_human def: "Casein kinase I isoform gamma-2 gene" [UniProtKB:P78368] xref: EMBL:AC005306 xref: EMBL:AF001177 xref: EMBL:BC018693 xref: EMBL:BC018699 xref: EMBL:BC020972 xref: EMBL:BT009922 xref: EMBL:U89896 xref: HGNC:HGNC:2455 xref: UniGene:Hs.651905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020420 ! KC1G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018382 name: CSNK1G3_human def: "Casein kinase I isoform gamma-3 gene" [UniProtKB:Q9Y6M4] xref: EMBL:AF049089 xref: EMBL:AF049090 xref: EMBL:BC047567 xref: HGNC:HGNC:2456 xref: UniGene:Hs.129206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020414 ! KC1G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018383 name: CAMK2B_human def: "Calcium/calmodulin-dependent protein kinase type II beta chain gene" [UniProtKB:Q13554] synonym: "CAM2" EXACT [UniProtKB:Q13554] synonym: "CAMKB" EXACT [UniProtKB:Q13554] xref: EMBL:AF078803 xref: EMBL:AF081572 xref: EMBL:AF081924 xref: EMBL:AF083419 xref: EMBL:AF112471 xref: EMBL:AF112472 xref: EMBL:AF140350 xref: EMBL:AJ252236 xref: EMBL:AJ252237 xref: EMBL:AJ252238 xref: EMBL:BC019070 xref: EMBL:U23460 xref: EMBL:U50358 xref: HGNC:HGNC:1461 xref: UniGene:Hs.351887 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016545 ! KCC2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018384 name: CAMK2D_human def: "Calcium/calmodulin-dependent protein kinase type II delta chain gene" [UniProtKB:Q13557] synonym: "CAMKD" EXACT [UniProtKB:Q13557] xref: EMBL:AB209288 xref: EMBL:AF071569 xref: EMBL:AJ252239 xref: EMBL:AY987011 xref: EMBL:BC032784 xref: EMBL:U50361 xref: HGNC:HGNC:1462 xref: UniGene:Hs.144114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016505 ! KCC2D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018385 name: KCTD13_human def: "BTB/POZ domain-containing protein KCTD13 gene" [UniProtKB:Q8WZ19] synonym: "FKSG86" EXACT [UniProtKB:Q8WZ19] synonym: "PDIP1" EXACT [UniProtKB:Q8WZ19] synonym: "POLDIP1" EXACT [UniProtKB:Q8WZ19] synonym: "PP6832" EXACT [UniProtKB:Q8WZ19] xref: EMBL:AF289573 xref: EMBL:AF401315 xref: EMBL:AY027918 xref: EMBL:BC036228 xref: HGNC:HGNC:22234 xref: UniGene:Hs.534590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058049 ! KCD13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018386 name: KCNIP1_human def: "Kv channel-interacting protein 1 gene" [UniProtKB:Q9NZI2] synonym: "KCHIP1" EXACT [UniProtKB:Q9NZI2] synonym: "VABP" EXACT [UniProtKB:Q9NZI2] xref: EMBL:AF199597 xref: EMBL:AY170821 xref: EMBL:AY780424 xref: EMBL:BC050375 xref: HGNC:HGNC:15521 xref: UniGene:Hs.484111 xref: UniGene:Hs.689588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020207 ! KCIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018387 name: KCNIP2_human def: "Kv channel-interacting protein 2 gene" [UniProtKB:Q9NS61] synonym: "KCHIP2" EXACT [UniProtKB:Q9NS61] xref: EMBL:AB044584 xref: EMBL:AB044585 xref: EMBL:AF199598 xref: EMBL:AF295076 xref: EMBL:AF295530 xref: EMBL:AF347114 xref: EMBL:AF367018 xref: EMBL:AF367019 xref: EMBL:AF367020 xref: EMBL:AF367021 xref: EMBL:AJ276317 xref: EMBL:AK027347 xref: EMBL:AL136722 xref: EMBL:AY026328 xref: EMBL:AY026329 xref: EMBL:AY026330 xref: EMBL:AY026331 xref: EMBL:AY302141 xref: EMBL:BC034685 xref: HGNC:HGNC:15522 xref: UniGene:Hs.97044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020223 ! KCIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018388 name: KCNMA1_human def: "Calcium-activated potassium channel subunit alpha-1 gene" [UniProtKB:Q12791] synonym: "KCNMA" EXACT [UniProtKB:Q12791] synonym: "SLO" EXACT [UniProtKB:Q12791] xref: EMBL:AB113382 xref: EMBL:AB113575 xref: EMBL:AC011439 xref: EMBL:AC021032 xref: EMBL:AF025999 xref: EMBL:AF118141 xref: EMBL:AL157833 xref: EMBL:AL627447 xref: EMBL:AL731556 xref: EMBL:AL731560 xref: EMBL:AY040849 xref: EMBL:BC062659 xref: EMBL:U02632 xref: EMBL:U09384 xref: EMBL:U11058 xref: EMBL:U11717 xref: EMBL:U13913 xref: EMBL:U23767 xref: HGNC:HGNC:6284 xref: UniGene:Hs.144795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055840 ! KCMA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018389 name: KCNMB4_human def: "Calcium-activated potassium channel subunit beta-4 gene" [UniProtKB:Q86W47] xref: EMBL:AF160967 xref: EMBL:AF170917 xref: EMBL:AF207992 xref: EMBL:AF215891 xref: EMBL:BC042446 xref: EMBL:BC050621 xref: HGNC:HGNC:6289 xref: UniGene:Hs.525529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057273 ! KCMB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018390 name: KCNH1_human def: "Potassium voltage-gated channel subfamily H member 1 gene" [UniProtKB:O95259] synonym: "EAG" EXACT [UniProtKB:O95259] synonym: "EAG1" EXACT [UniProtKB:O95259] xref: EMBL:AF078741 xref: EMBL:AF078742 xref: EMBL:AJ001366 xref: HGNC:HGNC:6250 xref: UniGene:Hs.662282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054741 ! KCNH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018391 name: KCNH2_human def: "Potassium voltage-gated channel subfamily H member 2 gene" [UniProtKB:Q12809] synonym: "ERG" EXACT [UniProtKB:Q12809] synonym: "ERG1" EXACT [UniProtKB:Q12809] synonym: "HERG" EXACT [UniProtKB:Q12809] synonym: "HERG1" EXACT [UniProtKB:Q12809] xref: EMBL:AB009071 xref: EMBL:AB044806 xref: EMBL:AF052728 xref: EMBL:AF363636 xref: EMBL:AJ010538 xref: EMBL:AJ010539 xref: EMBL:AJ010540 xref: EMBL:AJ010541 xref: EMBL:AJ010542 xref: EMBL:AJ010543 xref: EMBL:AJ010544 xref: EMBL:AJ010545 xref: EMBL:AJ010546 xref: EMBL:AJ010547 xref: EMBL:AJ010548 xref: EMBL:AJ010549 xref: EMBL:AJ010550 xref: EMBL:AJ010551 xref: EMBL:AJ512214 xref: EMBL:BC001914 xref: EMBL:BC004311 xref: EMBL:U04270 xref: HGNC:HGNC:6251 xref: UniGene:Hs.647099 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055844 ! KCNH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018392 name: KCNH3_human def: "Potassium voltage-gated channel subfamily H member 3 gene" [UniProtKB:Q9ULD8] synonym: "KIAA1282" EXACT [UniProtKB:Q9ULD8] xref: EMBL:AB022696 xref: EMBL:AB033108 xref: HGNC:HGNC:6252 xref: UniGene:Hs.64064 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059223 ! KCNH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018393 name: KCNH4_human def: "Potassium voltage-gated channel subfamily H member 4 gene" [UniProtKB:Q9UQ05] xref: EMBL:AB022698 xref: HGNC:HGNC:6253 xref: UniGene:Hs.304081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059273 ! KCNH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018394 name: KCNH5_human def: "Potassium voltage-gated channel subfamily H member 5 gene" [UniProtKB:Q8NCM2] synonym: "EAG2" EXACT [UniProtKB:Q8NCM2] xref: EMBL:AF418206 xref: EMBL:AF472412 xref: EMBL:AF493798 xref: EMBL:AK074484 xref: EMBL:BC043409 xref: EMBL:BC073979 xref: HGNC:HGNC:6254 xref: UniGene:Hs.27043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057288 ! Q86XI1_HUMAN relationship: codes_for CCO:B0057570 ! KCNH5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018395 name: KCNH6_human def: "Potassium voltage-gated channel subfamily H member 6 gene" [UniProtKB:Q9H252] synonym: "ERG2" EXACT [UniProtKB:Q9H252] synonym: "HERG2" EXACT [UniProtKB:Q9H252] xref: EMBL:AF311913 xref: EMBL:AK090969 xref: EMBL:AK091877 xref: EMBL:BC006334 xref: HGNC:HGNC:18862 xref: UniGene:Hs.591177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058676 ! KCNH6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018396 name: KCNH7_human def: "Potassium voltage-gated channel subfamily H member 7 gene" [UniProtKB:Q9NS40] synonym: "ERG3" EXACT [UniProtKB:Q9NS40] xref: EMBL:AF032897 xref: EMBL:BC035815 xref: HGNC:HGNC:18863 xref: UniGene:Hs.657413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057333 ! Q8IV15_HUMAN relationship: codes_for CCO:B0058908 ! KCNH7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018397 name: KCNH8_human def: "Potassium voltage-gated channel subfamily H member 8 gene" [UniProtKB:Q96L42] xref: EMBL:AY053503 xref: HGNC:HGNC:18864 xref: UniGene:Hs.475656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058265 ! KCNH8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018398 name: KCNK2_human def: "Potassium channel subfamily K member 2 gene" [UniProtKB:O95069] synonym: "TREK" EXACT [UniProtKB:O95069] synonym: "TREK1" EXACT [UniProtKB:O95069] xref: EMBL:AF004711 xref: EMBL:AF129399 xref: EMBL:AF171068 xref: EMBL:AY552980 xref: EMBL:BC069462 xref: EMBL:BC101693 xref: EMBL:BC101695 xref: EMBL:EF165334 xref: EMBL:EF165335 xref: HGNC:HGNC:6277 xref: UniGene:Hs.497745 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054718 ! KCNK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018399 name: KCNK10_human def: "Potassium channel subfamily K member 10 gene" [UniProtKB:P57789] synonym: "TREK2" EXACT [UniProtKB:P57789] xref: EMBL:AF279890 xref: EMBL:AF385399 xref: EMBL:AF385400 xref: HGNC:HGNC:6273 xref: UniGene:Hs.592299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055563 ! KCNKA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018400 name: KEAP1_human def: "Kelch-like ECH-associated protein 1 gene" [UniProtKB:Q14145] synonym: "INRF2" EXACT [UniProtKB:Q14145] synonym: "KIAA0132" EXACT [UniProtKB:Q14145] synonym: "KLHL19" EXACT [UniProtKB:Q14145] xref: EMBL:AF361886 xref: EMBL:AF361888 xref: EMBL:AF361889 xref: EMBL:AF361890 xref: EMBL:AF361891 xref: EMBL:AF361892 xref: EMBL:BC002417 xref: EMBL:BC002930 xref: EMBL:BC015945 xref: EMBL:D50922 xref: HGNC:HGNC:23177 xref: UniGene:Hs.465870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055962 ! KEAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018401 name: PRKG1_human def: "cGMP-dependent protein kinase 1, alpha isozyme gene" [UniProtKB:Q13976] synonym: "PRKGR1A" EXACT [UniProtKB:Q13976] xref: EMBL:AC009986 xref: EMBL:AC022025 xref: EMBL:AC022537 xref: EMBL:AC026228 xref: EMBL:AC027118 xref: EMBL:AL157399 xref: EMBL:AL391378 xref: EMBL:AL731537 xref: EMBL:AL928686 xref: EMBL:BC127090 xref: EMBL:D45864 xref: EMBL:Y07512 xref: EMBL:Z92867 xref: EMBL:Z92868 xref: EMBL:Z92869 xref: EMBL:Z92870 xref: EMBL:Z92871 xref: EMBL:Z92872 xref: EMBL:Z92873 xref: EMBL:Z92874 xref: EMBL:Z92875 xref: EMBL:Z92876 xref: EMBL:Z92877 xref: EMBL:Z92878 xref: EMBL:Z92879 xref: EMBL:Z92880 xref: EMBL:Z92881 xref: EMBL:Z92882 xref: EMBL:Z92883 xref: EMBL:Z92884 xref: EMBL:Z92885 xref: HGNC:HGNC:9414 xref: UniGene:Hs.654556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014816 ! KGP1A_HUMAN relationship: codes_for CCO:B0014822 ! KGP1B_HUMAN relationship: codes_for CCO:B0054240 ! B1ALS0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018402 name: KIR2DL4_human def: "Killer cell immunoglobulin-like receptor 2DL4 precursor gene" [UniProtKB:Q99706] synonym: "CD158D" EXACT [UniProtKB:Q99706] synonym: "KIR103AS" EXACT [UniProtKB:Q99706] xref: EMBL:AF002979 xref: EMBL:AF002980 xref: EMBL:AF002981 xref: EMBL:AF002982 xref: EMBL:AF003116 xref: EMBL:AF003117 xref: EMBL:AF003118 xref: EMBL:AF003119 xref: EMBL:AF003120 xref: EMBL:AF003121 xref: EMBL:AF003122 xref: EMBL:AF003123 xref: EMBL:AF034771 xref: EMBL:AF034772 xref: EMBL:AF034773 xref: EMBL:AF110032 xref: EMBL:AF110033 xref: EMBL:AF110034 xref: EMBL:AF110035 xref: EMBL:U71199 xref: EMBL:U73394 xref: EMBL:X97229 xref: EMBL:X99479 xref: EMBL:X99480 xref: EMBL:X99481 xref: HGNC:HGNC:6332 xref: UniGene:Hs.651287 xref: UniGene:Hs.661219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058445 ! KI2L4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018403 name: KIFAP3_human def: "Kinesin-associated protein 3 gene" [UniProtKB:Q92845] synonym: "SMAP" EXACT [UniProtKB:Q92845] xref: EMBL:AL121714 xref: EMBL:AL356475 xref: EMBL:BC028679 xref: EMBL:U59919 xref: HGNC:HGNC:17060 xref: UniGene:Hs.433442 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058104 ! KIFA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018404 name: KISS1R_human def: "KiSS-1 receptor gene" [UniProtKB:Q969F8] synonym: "AXOR12" EXACT [UniProtKB:Q969F8] synonym: "GPR54" EXACT [UniProtKB:Q969F8] synonym: "OT7T175" EXACT [UniProtKB:Q969F8] xref: EMBL:AB051065 xref: EMBL:AC005379 xref: EMBL:AF343725 xref: EMBL:AJ309020 xref: EMBL:AY029541 xref: EMBL:AY253981 xref: EMBL:AY253982 xref: HGNC:HGNC:4510 xref: UniGene:Hs.208229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058129 ! KISSR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018405 name: TK2_human def: "Thymidine kinase 2, mitochondrial precursor gene" [UniProtKB:O00142] xref: EMBL:U77088 xref: EMBL:Y10498 xref: HGNC:HGNC:11831 xref: UniGene:Hs.512619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054290 ! KITM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018406 name: KIT_human def: "Mast/stem cell growth factor receptor precursor gene" [UniProtKB:P10721] xref: EMBL:AK304031 xref: EMBL:S67773 xref: EMBL:U63834 xref: EMBL:X06182 xref: EMBL:X69301 xref: EMBL:X69302 xref: EMBL:X69303 xref: EMBL:X69304 xref: EMBL:X69305 xref: EMBL:X69306 xref: EMBL:X69307 xref: EMBL:X69308 xref: EMBL:X69309 xref: EMBL:X69310 xref: EMBL:X69311 xref: EMBL:X69312 xref: EMBL:X69313 xref: EMBL:X69314 xref: EMBL:X69315 xref: EMBL:X69316 xref: HGNC:HGNC:6342 xref: UniGene:Hs.479754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054977 ! KIT_HUMAN relationship: codes_for CCO:B0058436 ! Q99662_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018407 name: CAMKK2_human def: "Calcium/calmodulin-dependent protein kinase kinase 2 gene" [UniProtKB:Q96RR4] synonym: "CAMKKB" EXACT [UniProtKB:Q96RR4] synonym: "KIAA0787" EXACT [UniProtKB:Q96RR4] xref: EMBL:AB018330 xref: EMBL:AB081336 xref: EMBL:AB081337 xref: EMBL:AF091074 xref: EMBL:AF101264 xref: EMBL:AF140507 xref: EMBL:AF287630 xref: EMBL:AF287631 xref: EMBL:AF321385 xref: EMBL:AF321386 xref: EMBL:AF321387 xref: EMBL:AF321388 xref: EMBL:AF321390 xref: EMBL:AF321391 xref: EMBL:AF321392 xref: EMBL:AF321393 xref: EMBL:AF321394 xref: EMBL:AF321395 xref: EMBL:AF321396 xref: EMBL:AF321397 xref: EMBL:AF321398 xref: EMBL:AF321399 xref: EMBL:AF321400 xref: EMBL:AF321401 xref: EMBL:AF321402 xref: EMBL:AF321575 xref: EMBL:AF321576 xref: EMBL:AF321577 xref: EMBL:AF321578 xref: EMBL:AL834322 xref: EMBL:BC000318 xref: EMBL:BC026060 xref: HGNC:HGNC:1470 xref: UniGene:Hs.297343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058383 ! KKCC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018408 name: KLF10_human def: "Krueppel-like factor 10 gene" [UniProtKB:Q13118] synonym: "TIEG" EXACT [UniProtKB:Q13118] synonym: "TIEG1" EXACT [UniProtKB:Q13118] xref: EMBL:AF050110 xref: EMBL:BC095399 xref: EMBL:U21847 xref: HGNC:HGNC:11810 xref: UniGene:Hs.435001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055875 ! KLF10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018409 name: KLF11_human def: "Krueppel-like factor 11 gene" [UniProtKB:O14901] synonym: "FKLF" EXACT [UniProtKB:O14901] synonym: "TIEG2" EXACT [UniProtKB:O14901] xref: EMBL:AF028008 xref: EMBL:AF272830 xref: EMBL:BC063286 xref: EMBL:BC069383 xref: EMBL:BC074922 xref: HGNC:HGNC:11811 xref: UniGene:Hs.12229 xref: UniGene:Hs.694968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054387 ! KLF11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018410 name: KLF12_human def: "Krueppel-like factor 12 gene" [UniProtKB:Q9Y4X4] synonym: "AP2REP" EXACT [UniProtKB:Q9Y4X4] synonym: "HSPC122" EXACT [UniProtKB:Q9Y4X4] xref: EMBL:AF113122 xref: EMBL:AF161471 xref: EMBL:AF312866 xref: EMBL:AF312867 xref: EMBL:AF312868 xref: EMBL:AF312869 xref: EMBL:AF312870 xref: EMBL:AF312871 xref: EMBL:AF312872 xref: EMBL:AJ243274 xref: EMBL:AL138713 xref: EMBL:AL139036 xref: EMBL:AL159972 xref: EMBL:AL160032 xref: EMBL:BC019680 xref: HGNC:HGNC:6346 xref: UniGene:Hs.373857 xref: UniGene:Hs.592500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059366 ! KLF12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018411 name: KLF13_human def: "Krueppel-like factor 13 gene" [UniProtKB:Q9Y2Y9] synonym: "BTEB3" EXACT [UniProtKB:Q9Y2Y9] synonym: "NSLP1" EXACT [UniProtKB:Q9Y2Y9] xref: EMBL:AF132599 xref: EMBL:AF150628 xref: EMBL:BC010438 xref: EMBL:BC012741 xref: EMBL:BC013946 xref: HGNC:HGNC:13672 xref: UniGene:Hs.525752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059326 ! KLF13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018412 name: KLF14_human def: "Krueppel-like factor 14 gene" [UniProtKB:Q8TD94] synonym: "BTEB5" EXACT [UniProtKB:Q8TD94] xref: EMBL:AF490374 xref: EMBL:DQ534756 xref: EMBL:DQ534757 xref: HGNC:HGNC:23025 xref: UniGene:Hs.125240 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057922 ! KLF14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018413 name: KLF15_human def: "Krueppel-like factor 15 gene" [UniProtKB:Q9UIH9] synonym: "KKLF" EXACT [UniProtKB:Q9UIH9] xref: EMBL:AB029254 xref: EMBL:BC036733 xref: HGNC:HGNC:14536 xref: UniGene:Hs.272215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059162 ! KLF15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018414 name: KLF16_human def: "Krueppel-like factor 16 gene" [UniProtKB:Q9BXK1] synonym: "BTEB4" EXACT [UniProtKB:Q9BXK1] synonym: "NSLP2" EXACT [UniProtKB:Q9BXK1] xref: EMBL:AF327440 xref: HGNC:HGNC:16857 xref: UniGene:Hs.136280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058557 ! KLF16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018415 name: KLF17_human def: "Krueppel-like factor 17 gene" [UniProtKB:Q5JT82] synonym: "ZNF393" EXACT [UniProtKB:Q5JT82] xref: EMBL:AK097479 xref: EMBL:AL356653 xref: EMBL:BC049844 xref: HGNC:HGNC:18830 xref: UniGene:Hs.567674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056483 ! KLF17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018416 name: KLF1_human def: "Krueppel-like factor 1 gene" [UniProtKB:Q13351] synonym: "EKLF" EXACT [UniProtKB:Q13351] xref: EMBL:AD000092 xref: EMBL:BC033580 xref: EMBL:U37106 xref: EMBL:U65404 xref: HGNC:HGNC:6345 xref: UniGene:Hs.37860 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055900 ! KLF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018417 name: KLF2_human def: "Krueppel-like factor 2 gene" [UniProtKB:Q9Y5W3] synonym: "LKLF" EXACT [UniProtKB:Q9Y5W3] xref: EMBL:AF123344 xref: EMBL:AF134053 xref: EMBL:AF205849 xref: EMBL:BC071983 xref: EMBL:EF078888 xref: HGNC:HGNC:6347 xref: UniGene:Hs.107740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059388 ! KLF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018418 name: KLF3_human def: "Krueppel-like factor 3 gene" [UniProtKB:P57682] synonym: "BKLF" EXACT [UniProtKB:P57682] xref: EMBL:AB024523 xref: EMBL:AF285837 xref: EMBL:BC030662 xref: EMBL:BC051687 xref: HGNC:HGNC:16516 xref: UniGene:Hs.298658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055559 ! KLF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018419 name: KLF4_human def: "Krueppel-like factor 4 gene" [UniProtKB:O43474] synonym: "EZF" EXACT [UniProtKB:O43474] synonym: "GKLF" EXACT [UniProtKB:O43474] xref: EMBL:AF022184 xref: EMBL:AF105036 xref: EMBL:AL360218 xref: EMBL:BC029923 xref: EMBL:BC030811 xref: EMBL:CH471105 xref: EMBL:DQ658241 xref: EMBL:U70663 xref: HGNC:HGNC:6348 xref: UniGene:Hs.376206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054483 ! KLF4_HUMAN relationship: codes_for CCO:B0057496 ! Q8N717_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018420 name: KLF5_human def: "Krueppel-like factor 5 gene" [UniProtKB:Q13887] synonym: "BTEB2" EXACT [UniProtKB:Q13887] synonym: "CKLF" EXACT [UniProtKB:Q13887] synonym: "IKLF" EXACT [UniProtKB:Q13887] xref: EMBL:AB030824 xref: EMBL:AF132818 xref: EMBL:AF287272 xref: EMBL:BC007695 xref: EMBL:BC042131 xref: EMBL:D14520 xref: HGNC:HGNC:6349 xref: UniGene:Hs.508234 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055950 ! KLF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018421 name: KLF6_human def: "Krueppel-like factor 6 gene" [UniProtKB:Q99612] synonym: "BCD1" EXACT [UniProtKB:Q99612] synonym: "COPEB" EXACT [UniProtKB:Q99612] synonym: "CPBP" EXACT [UniProtKB:Q99612] synonym: "ST12" EXACT [UniProtKB:Q99612] xref: EMBL:AB017493 xref: EMBL:AF001461 xref: EMBL:AF284036 xref: EMBL:AL450322 xref: EMBL:AL513303 xref: EMBL:BC000311 xref: EMBL:BT006778 xref: EMBL:U44975 xref: HGNC:HGNC:2235 xref: UniGene:Hs.4055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058431 ! KLF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018422 name: KLF7_human def: "Krueppel-like factor 7 gene" [UniProtKB:O75840] synonym: "UKLF" EXACT [UniProtKB:O75840] xref: EMBL:AB015132 xref: EMBL:CR542112 xref: HGNC:HGNC:6350 xref: UniGene:Hs.471221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054673 ! KLF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018423 name: KLF8_human def: "Krueppel-like factor 8 gene" [UniProtKB:O95600] synonym: "BKLF3" EXACT [UniProtKB:O95600] synonym: "ZNF741" EXACT [UniProtKB:O95600] xref: EMBL:AB209004 xref: EMBL:AL050309 xref: EMBL:BC105130 xref: EMBL:BC112109 xref: EMBL:BX322609 xref: EMBL:BX641066 xref: EMBL:U28282 xref: HGNC:HGNC:6351 xref: UniGene:Hs.646614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054772 ! KLF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018424 name: KLF9_human def: "Krueppel-like factor 9 gene" [UniProtKB:Q13886] synonym: "BTEB" EXACT [UniProtKB:Q13886] synonym: "BTEB1" EXACT [UniProtKB:Q13886] xref: EMBL:AL162390 xref: EMBL:BC069431 xref: EMBL:BC074879 xref: EMBL:BC074880 xref: EMBL:D31716 xref: EMBL:S72504 xref: HGNC:HGNC:1123 xref: UniGene:Hs.150557 xref: UniGene:Hs.602267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055949 ! KLF9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018425 name: KLHL12_human def: "Kelch-like protein 12 gene" [UniProtKB:Q53G59] synonym: "C3IP1" EXACT [UniProtKB:Q53G59] xref: EMBL:AF190900 xref: EMBL:AK027656 xref: EMBL:AK223072 xref: EMBL:BC003183 xref: EMBL:BC004175 xref: HGNC:HGNC:19360 xref: UniGene:Hs.282878 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056358 ! KLH12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018426 name: KL_human def: "Klotho precursor gene" [UniProtKB:Q9UEF7] xref: EMBL:AB005142 xref: EMBL:AB009667 xref: EMBL:AL161898 xref: EMBL:Z84483 xref: EMBL:Z92540 xref: HGNC:HGNC:6344 xref: UniGene:Hs.524953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059108 ! KLOT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018427 name: KLRB1_human def: "Killer cell lectin-like receptor subfamily B member 1 gene" [UniProtKB:Q12918] synonym: "CLEC5B" EXACT [UniProtKB:Q12918] synonym: "NKRP1A" EXACT [UniProtKB:Q12918] xref: EMBL:BC113997 xref: EMBL:BC114516 xref: EMBL:U11276 xref: HGNC:HGNC:6373 xref: UniGene:Hs.169824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055857 ! KLRB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018428 name: KLRD1_human def: "Natural killer cells antigen CD94 gene" [UniProtKB:Q13241] synonym: "CD94" EXACT [UniProtKB:Q13241] xref: EMBL:AB009597 xref: EMBL:AB010084 xref: EMBL:AJ000001 xref: EMBL:AJ000673 xref: EMBL:BC028009 xref: EMBL:U30610 xref: EMBL:Y14287 xref: EMBL:Y14288 xref: HGNC:HGNC:6378 xref: UniGene:Hs.562457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055889 ! KLRD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018429 name: KLRF1_human def: "Killer cell lectin-like receptor subfamily F member 1 gene" [UniProtKB:Q9NZS2] synonym: "ML" EXACT [UniProtKB:Q9NZS2] xref: EMBL:AC007068 xref: EMBL:AF175206 xref: EMBL:AF175207 xref: EMBL:AF267244 xref: EMBL:AF267245 xref: EMBL:AJ305370 xref: EMBL:BC098354 xref: HGNC:HGNC:13342 xref: UniGene:Hs.183125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059014 ! KLRF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018430 name: KLRG1_human def: "Killer cell lectin-like receptor subfamily G member 1 gene" [UniProtKB:Q96E93] synonym: "CLEC15A" EXACT [UniProtKB:Q96E93] synonym: "MAFA" EXACT [UniProtKB:Q96E93] synonym: "MAFAL" EXACT [UniProtKB:Q96E93] xref: EMBL:AF034952 xref: EMBL:AF081675 xref: EMBL:AF097358 xref: EMBL:BC012621 xref: EMBL:CH471116 xref: HGNC:HGNC:6380 xref: UniGene:Hs.558446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058202 ! KLRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018431 name: KNG1_human def: "Kininogen-1 precursor gene" [UniProtKB:P01042] synonym: "BDK" EXACT [UniProtKB:P01042] synonym: "KNG" EXACT [UniProtKB:P01042] xref: EMBL:AY248697 xref: EMBL:K02566 xref: EMBL:M11437 xref: EMBL:M11438 xref: EMBL:M11521 xref: EMBL:M11522 xref: EMBL:M11523 xref: EMBL:M11524 xref: EMBL:M11525 xref: EMBL:M11526 xref: EMBL:M11527 xref: EMBL:M11528 xref: HGNC:HGNC:6383 xref: UniGene:Hs.77741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054832 ! KNG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018432 name: PRKCB_human def: "Protein kinase C beta type gene" [UniProtKB:P05771] synonym: "PKCB" EXACT [UniProtKB:P05771] synonym: "PRKCB1" EXACT [UniProtKB:P05771] xref: EMBL:AC002299 xref: EMBL:AC130454 xref: EMBL:AJ002799 xref: EMBL:AJ002800 xref: EMBL:BC036472 xref: EMBL:D10022 xref: EMBL:M13975 xref: EMBL:M18254 xref: EMBL:M18255 xref: EMBL:S47311 xref: EMBL:X05971 xref: EMBL:X05972 xref: EMBL:X06318 xref: EMBL:X07109 xref: EMBL:X62532 xref: HGNC:HGNC:9395 xref: UniGene:Hs.460355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025045 ! KPCB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018433 name: PRKD2_human def: "Serine/threonine-protein kinase D2 gene" [UniProtKB:Q9BZL6] synonym: "HSPC187" EXACT [UniProtKB:Q9BZL6] synonym: "PKD2" EXACT [UniProtKB:Q9BZL6] xref: EMBL:AF151021 xref: EMBL:AF309082 xref: EMBL:AL050147 xref: HGNC:HGNC:17293 xref: UniGene:Hs.466987 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058604 ! KPCD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018434 name: PRKD3_human def: "Serine/threonine-protein kinase D3 gene" [UniProtKB:O94806] synonym: "EPK2" EXACT [UniProtKB:O94806] synonym: "PRKCN" EXACT [UniProtKB:O94806] xref: EMBL:AB015982 xref: EMBL:BC030706 xref: HGNC:HGNC:9408 xref: UniGene:Hs.660757 xref: UniGene:Hs.696257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054699 ! KPCD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018435 name: PRKCD_human def: "Protein kinase C delta type gene" [UniProtKB:Q05655] xref: EMBL:AK313216 xref: EMBL:BC043350 xref: EMBL:CH471055 xref: EMBL:D10495 xref: EMBL:L07860 xref: EMBL:L07861 xref: EMBL:Z22521 xref: HGNC:HGNC:9399 xref: UniGene:Hs.155342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055745 ! KPCD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018436 name: KRBA2_human def: "KRAB-A domain-containing protein 2 gene" [UniProtKB:Q6ZNG9] xref: EMBL:AK131219 xref: EMBL:BC033390 xref: HGNC:HGNC:26989 xref: UniGene:Hs.304604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057025 ! KRBA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018437 name: KREMEN1_human def: "Kremen protein 1 precursor gene" [UniProtKB:Q96MU8] synonym: "KREMEN" EXACT [UniProtKB:Q96MU8] synonym: "KRM1" EXACT [UniProtKB:Q96MU8] xref: EMBL:AB059618 xref: EMBL:AK056425 xref: EMBL:AL021393 xref: EMBL:BC063787 xref: EMBL:CH471095 xref: EMBL:Z95116 xref: HGNC:HGNC:17550 xref: UniGene:Hs.229335 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058294 ! KREM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018438 name: KREMEN2_human def: "Kremen protein 2 precursor gene" [UniProtKB:Q8NCW0] synonym: "KRM2" EXACT [UniProtKB:Q8NCW0] xref: EMBL:AB086355 xref: EMBL:AB086356 xref: EMBL:AB086357 xref: EMBL:AB086405 xref: EMBL:AK027669 xref: EMBL:AK075033 xref: EMBL:BC003533 xref: EMBL:BC009383 xref: HGNC:HGNC:18797 xref: UniGene:Hs.661128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057574 ! KREM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018439 name: KRIT1_human def: "Krev interaction trapped protein 1 gene" [UniProtKB:O00522] synonym: "CCM1" EXACT [UniProtKB:O00522] xref: EMBL:AC000120 xref: EMBL:AF296765 xref: EMBL:AF310133 xref: EMBL:AF388384 xref: EMBL:AJ294850 xref: EMBL:AY380057 xref: EMBL:AY993945 xref: EMBL:BC094684 xref: EMBL:BC098442 xref: EMBL:U90268 xref: EMBL:U90269 xref: HGNC:HGNC:1573 xref: UniGene:Hs.531987 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054330 ! KRIT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018440 name: RPS6KA1_human def: "Ribosomal protein S6 kinase alpha-1 gene" [UniProtKB:Q15418] synonym: "RSK1" EXACT [UniProtKB:Q15418] xref: EMBL:AL109743 xref: EMBL:AL627313 xref: EMBL:BC014966 xref: EMBL:L07597 xref: HGNC:HGNC:10430 xref: UniGene:Hs.149957 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028627 ! KS6A1_HUMAN relationship: codes_for CCO:B0028635 ! A6NGG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018441 name: RPS6KA2_human def: "Ribosomal protein S6 kinase alpha-2 gene" [UniProtKB:Q15349] synonym: "RSK3" EXACT [UniProtKB:Q15349] xref: EMBL:AB209116 xref: EMBL:AL022069 xref: EMBL:BC002363 xref: EMBL:L07598 xref: EMBL:X85106 xref: EMBL:Z98049 xref: HGNC:HGNC:10431 xref: UniGene:Hs.655277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028634 ! KS6A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018442 name: RPS6KA3_human def: "Ribosomal protein S6 kinase alpha-3 gene" [UniProtKB:P51812] synonym: "ISPK1" EXACT [UniProtKB:P51812] synonym: "RSK2" EXACT [UniProtKB:P51812] xref: EMBL:AB102662 xref: EMBL:AB208933 xref: EMBL:AL732366 xref: EMBL:AL807772 xref: EMBL:BC096301 xref: EMBL:BC096302 xref: EMBL:BC096303 xref: EMBL:L07599 xref: EMBL:U08316 xref: HGNC:HGNC:10432 xref: UniGene:Hs.445387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028618 ! KS6A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018443 name: RPS6KA5_human def: "Ribosomal protein S6 kinase alpha-5 gene" [UniProtKB:O75582] synonym: "MSK1" EXACT [UniProtKB:O75582] xref: EMBL:AF074393 xref: EMBL:AF080000 xref: EMBL:AF090421 xref: EMBL:BC017187 xref: HGNC:HGNC:10434 xref: UniGene:Hs.510225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054653 ! KS6A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018444 name: RPS6KA6_human def: "Ribosomal protein S6 kinase alpha-6 gene" [UniProtKB:Q9UK32] synonym: "RSK4" EXACT [UniProtKB:Q9UK32] xref: EMBL:AF184965 xref: EMBL:AL354653 xref: EMBL:AL389887 xref: EMBL:CR536566 xref: HGNC:HGNC:10435 xref: UniGene:Hs.368153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028620 ! KS6A6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018445 name: RPS6KB1_human def: "Ribosomal protein S6 kinase beta-1 gene" [UniProtKB:P23443] synonym: "STK14A" EXACT [UniProtKB:P23443] xref: EMBL:BC053365 xref: EMBL:CH471109 xref: EMBL:M60724 xref: EMBL:M60725 xref: HGNC:HGNC:10436 xref: UniGene:Hs.463642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028628 ! Q7Z721_HUMAN relationship: codes_for CCO:B0028633 ! KS6B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018446 name: RPS6KC1_human def: "Ribosomal protein S6 kinase delta-1 gene" [UniProtKB:Q96S38] synonym: "RPK118" EXACT [UniProtKB:Q96S38] xref: EMBL:AB070706 xref: EMBL:AF037447 xref: EMBL:AF477978 xref: EMBL:AL356893 xref: EMBL:AL512449 xref: EMBL:AL583826 xref: EMBL:AL645860 xref: EMBL:BC104769 xref: HGNC:HGNC:10439 xref: UniGene:Hs.591416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058385 ! KS6C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018447 name: KSR1_human def: "Kinase suppressor of Ras 1 gene" [UniProtKB:Q8IVT5] synonym: "KSR" EXACT [UniProtKB:Q8IVT5] xref: EMBL:AC015688 xref: EMBL:AC069366 xref: EMBL:BC042106 xref: EMBL:U43586 xref: HGNC:HGNC:6465 xref: UniGene:Hs.133534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054118 ! A8MY87_HUMAN relationship: codes_for CCO:B0057348 ! KSR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018448 name: KSR2_human def: "Kinase suppressor of Ras 2 gene" [UniProtKB:Q6VAB6] xref: EMBL:AC073864 xref: EMBL:AC079127 xref: EMBL:AC084291 xref: EMBL:AC092936 xref: EMBL:AK098831 xref: EMBL:AY345972 xref: EMBL:BC107106 xref: EMBL:BC107107 xref: EMBL:BC127603 xref: HGNC:HGNC:18610 xref: UniGene:Hs.375836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056960 ! KSR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018449 name: SYK_human def: "Tyrosine-protein kinase SYK gene" [UniProtKB:P43405] xref: EMBL:BC001645 xref: EMBL:BC002962 xref: EMBL:BC011399 xref: EMBL:L28824 xref: EMBL:X73568 xref: EMBL:Z29630 xref: HGNC:HGNC:11491 xref: UniGene:Hs.371720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055365 ! KSYK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018450 name: LAG3_human def: "Lymphocyte activation gene 3 protein precursor gene" [UniProtKB:P18627] synonym: "FDC" EXACT [UniProtKB:P18627] xref: EMBL:X51985 xref: HGNC:HGNC:6476 xref: UniGene:Hs.409523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055103 ! LAG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018451 name: LALBA_human def: "Alpha-lactalbumin precursor gene" [UniProtKB:P00709] synonym: "LYZL7" EXACT [UniProtKB:P00709] xref: EMBL:AB049976 xref: EMBL:BC069103 xref: EMBL:BC112316 xref: EMBL:BC112318 xref: EMBL:CH471111 xref: EMBL:CR541987 xref: EMBL:CR542017 xref: EMBL:J00270 xref: EMBL:X05153 xref: HGNC:HGNC:6480 xref: UniGene:Hs.72938 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054825 ! LALBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018452 name: LAMA1_human def: "Laminin subunit alpha-1 precursor gene" [UniProtKB:P25391] synonym: "LAMA" EXACT [UniProtKB:P25391] xref: EMBL:X58531 xref: HGNC:HGNC:6481 xref: UniGene:Hs.270364 xref: UniGene:Hs.680444 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055184 ! LAMA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018453 name: LAMA5_human def: "Laminin subunit alpha-5 precursor gene" [UniProtKB:O15230] synonym: "KIAA0533" EXACT [UniProtKB:O15230] synonym: "KIAA1907" EXACT [UniProtKB:O15230] xref: EMBL:AB011105 xref: EMBL:AB067494 xref: EMBL:AL354836 xref: EMBL:Z95636 xref: HGNC:HGNC:6485 xref: UniGene:Hs.473256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054418 ! LAMA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018454 name: LAMC1_human def: "Laminin subunit gamma-1 precursor gene" [UniProtKB:P11047] synonym: "LAMB2" EXACT [UniProtKB:P11047] xref: EMBL:J03202 xref: EMBL:M27654 xref: EMBL:M55192 xref: EMBL:M55193 xref: EMBL:M55194 xref: EMBL:M55195 xref: EMBL:M55196 xref: EMBL:M55197 xref: EMBL:M55198 xref: EMBL:M55199 xref: EMBL:M55200 xref: EMBL:M55201 xref: EMBL:M55202 xref: EMBL:M55203 xref: EMBL:M55204 xref: EMBL:M55205 xref: EMBL:M55206 xref: EMBL:M55207 xref: EMBL:M55208 xref: EMBL:M55209 xref: EMBL:M55210 xref: EMBL:M55211 xref: EMBL:M55212 xref: EMBL:M55213 xref: EMBL:M55214 xref: EMBL:M55215 xref: EMBL:M55216 xref: EMBL:M55217 xref: EMBL:X13939 xref: HGNC:HGNC:6492 xref: UniGene:Hs.609663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054985 ! LAMC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018455 name: LAMP3_human def: "Lysosome-associated membrane glycoprotein 3 precursor gene" [UniProtKB:Q9UQV4] synonym: "DCLAMP" EXACT [UniProtKB:Q9UQV4] synonym: "TSC403" EXACT [UniProtKB:Q9UQV4] xref: EMBL:AB013924 xref: EMBL:AJ005766 xref: EMBL:BC032940 xref: HGNC:HGNC:14582 xref: UniGene:Hs.518448 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059286 ! LAMP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018456 name: TMPO_human def: "Lamina-associated polypeptide 2, isoform alpha gene" [UniProtKB:P42166] synonym: "LAP2" EXACT [UniProtKB:P42166] xref: EMBL:S76736 xref: EMBL:U09086 xref: EMBL:U18266 xref: EMBL:U18267 xref: EMBL:U18268 xref: EMBL:U18270 xref: HGNC:HGNC:11875 xref: UniGene:Hs.11355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055348 ! LAP2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018457 name: LAT_human def: "Linker for activation of T-cells family member 1 gene" [UniProtKB:O43561] xref: EMBL:AF036905 xref: EMBL:AF036906 xref: EMBL:AJ223280 xref: EMBL:BC011563 xref: HGNC:HGNC:18874 xref: UniGene:Hs.632179 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054492 ! LAT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018458 name: LAX1_human def: "Lymphocyte transmembrane adapter 1 gene" [UniProtKB:Q8IWV1] synonym: "LAX" EXACT [UniProtKB:Q8IWV1] xref: EMBL:AK000347 xref: EMBL:AY090784 xref: EMBL:BC069650 xref: EMBL:BC089408 xref: HGNC:HGNC:26005 xref: UniGene:Hs.272794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057364 ! LAX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018459 name: LBH_human def: "Protein LBH gene" [UniProtKB:Q53QV2] xref: EMBL:AC104698 xref: EMBL:AK223541 xref: EMBL:AL136703 xref: EMBL:BC109376 xref: EMBL:BC126434 xref: EMBL:BC130415 xref: EMBL:EF025586 xref: HGNC:HGNC:29532 xref: UniGene:Hs.567598 xref: UniGene:Hs.593113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056363 ! LBH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018460 name: LBX1_human def: "Transcription factor LBX1 gene" [UniProtKB:P52954] synonym: "LBX1H" EXACT [UniProtKB:P52954] xref: EMBL:AL135794 xref: EMBL:BC069156 xref: EMBL:X90828 xref: HGNC:HGNC:16960 xref: UniGene:Hs.37128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055507 ! LBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018461 name: LBX2_human def: "Transcription factor LBX2 gene" [UniProtKB:Q6XYB7] synonym: "LP3727" EXACT [UniProtKB:Q6XYB7] xref: EMBL:AY203953 xref: EMBL:AY305861 xref: EMBL:BC150517 xref: EMBL:CH471053 xref: HGNC:HGNC:15525 xref: UniGene:Hs.554975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056972 ! LBX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018462 name: LBXCOR1_human def: "Ladybird homeobox corepressor 1 gene" [UniProtKB:P84550] synonym: "CORL1" EXACT [UniProtKB:P84550] synonym: "FUSSEL15" EXACT [UniProtKB:P84550] xref: EMBL:AC009292 xref: EMBL:AY669507 xref: HGNC:HGNC:21326 xref: UniGene:Hs.451224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055663 ! LBXCO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018463 name: LCORL_human def: "Ligand-dependent nuclear receptor corepressor-like protein gene" [UniProtKB:Q8N3X6] xref: EMBL:AC005768 xref: EMBL:AC079399 xref: EMBL:AK055258 xref: EMBL:BC037322 xref: EMBL:CH471069 xref: HGNC:HGNC:30776 xref: UniGene:Hs.446201 xref: UniGene:Hs.661849 xref: UniGene:Hs.677572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057458 ! LCORL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018464 name: LCOR_human def: "Ligand-dependent corepressor gene" [UniProtKB:Q96JN0] synonym: "KIAA1795" EXACT [UniProtKB:Q96JN0] synonym: "MLR2" EXACT [UniProtKB:Q96JN0] xref: EMBL:AB058698 xref: EMBL:AL442123 xref: EMBL:AL832044 xref: EMBL:AL832106 xref: EMBL:AL834245 xref: EMBL:BC053359 xref: HGNC:HGNC:29503 xref: UniGene:Hs.500695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058246 ! LCOR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018465 name: LCP2_human def: "Lymphocyte cytosolic protein 2 gene" [UniProtKB:Q13094] xref: EMBL:BC016618 xref: EMBL:U20158 xref: HGNC:HGNC:6529 xref: UniGene:Hs.304475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055872 ! LCP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018466 name: LDB1_human def: "LIM domain-binding protein 1 gene" [UniProtKB:Q86U70] synonym: "CLIM2" EXACT [UniProtKB:Q86U70] xref: EMBL:AB016485 xref: EMBL:AB250384 xref: EMBL:AF064491 xref: EMBL:AF068652 xref: EMBL:AJ243098 xref: EMBL:AL500527 xref: EMBL:BC000482 xref: EMBL:BC009246 xref: EMBL:BT007054 xref: HGNC:HGNC:6532 xref: UniGene:Hs.702266 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057244 ! LDB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018467 name: LECT1_human def: "Chondromodulin-1 precursor gene" [UniProtKB:O75829] synonym: "CHMI" EXACT [UniProtKB:O75829] xref: EMBL:AB005999 xref: EMBL:AB006000 xref: EMBL:AB021290 xref: EMBL:AF050147 xref: HGNC:HGNC:17005 xref: UniGene:Hs.421391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054672 ! LECT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018468 name: LEF1_human def: "Lymphoid enhancer-binding factor 1 gene" [UniProtKB:Q9UJU2] xref: EMBL:AF198532 xref: EMBL:AF288571 xref: EMBL:AF294627 xref: EMBL:BC040559 xref: EMBL:BC050632 xref: EMBL:CH471057 xref: HGNC:HGNC:6551 xref: UniGene:Hs.555947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056285 ! Q3ZCU4_HUMAN relationship: codes_for CCO:B0059175 ! LEF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018469 name: LGALS12_human def: "Galectin-12 gene" [UniProtKB:Q96DT0] synonym: "GRIP1" EXACT [UniProtKB:Q96DT0] xref: EMBL:AF222695 xref: EMBL:AF244974 xref: EMBL:AF244975 xref: EMBL:AF244976 xref: EMBL:AF244977 xref: EMBL:AF310686 xref: EMBL:AF310687 xref: EMBL:BC028222 xref: HGNC:HGNC:15788 xref: UniGene:Hs.502774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058197 ! LEG12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018470 name: LGALS1_human def: "Galectin-1 gene" [UniProtKB:P09382] xref: EMBL:AB097036 xref: EMBL:BC001693 xref: EMBL:BC020675 xref: EMBL:BT006775 xref: EMBL:CR456511 xref: EMBL:J04456 xref: EMBL:M57678 xref: EMBL:X14829 xref: EMBL:X15256 xref: EMBL:Z83844 xref: HGNC:HGNC:6561 xref: UniGene:Hs.445351 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054942 ! LEG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018471 name: LGALS9_human def: "Galectin-9 gene" [UniProtKB:O00182] xref: EMBL:AB005894 xref: EMBL:AB006782 xref: EMBL:AB040130 xref: EMBL:AJ288083 xref: EMBL:AJ288084 xref: EMBL:AJ288085 xref: EMBL:AJ288086 xref: EMBL:AJ288087 xref: EMBL:AJ288088 xref: EMBL:AJ288089 xref: EMBL:AJ288090 xref: EMBL:Z49107 xref: HGNC:HGNC:6570 xref: UniGene:Hs.81337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054296 ! LEG9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018472 name: LEO1_human def: "RNA polymerase-associated protein LEO1 gene" [UniProtKB:Q8WVC0] synonym: "RDL" EXACT [UniProtKB:Q8WVC0] xref: EMBL:AK055762 xref: EMBL:AY302186 xref: EMBL:BC018147 xref: HGNC:HGNC:30401 xref: UniGene:Hs.567662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057990 ! LEO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018473 name: LEP_human def: "Leptin precursor gene" [UniProtKB:P41159] synonym: "OB" EXACT [UniProtKB:P41159] synonym: "OBS" EXACT [UniProtKB:P41159] xref: EMBL:AF008123 xref: EMBL:AY996373 xref: EMBL:BC060830 xref: EMBL:BC069452 xref: EMBL:BC069527 xref: EMBL:D49487 xref: EMBL:D63519 xref: EMBL:D63710 xref: EMBL:U18915 xref: EMBL:U43415 xref: EMBL:U43653 xref: HGNC:HGNC:6553 xref: UniGene:Hs.194236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055333 ! LEP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018474 name: LETM1_human def: "LETM1 and EF-hand domain-containing protein 1, mitochondrial precursor gene" [UniProtKB:O95202] xref: EMBL:AF061025 xref: EMBL:AL133650 xref: EMBL:BC014500 xref: EMBL:BC021208 xref: HGNC:HGNC:6556 xref: UniGene:Hs.120165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025098 ! LETM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018475 name: SPN_human def: "Leukosialin precursor gene" [UniProtKB:P16150] synonym: "CD43" EXACT [UniProtKB:P16150] xref: EMBL:BC012350 xref: EMBL:J04168 xref: EMBL:J04536 xref: EMBL:M61827 xref: EMBL:X52075 xref: HGNC:HGNC:11249 xref: UniGene:Hs.632188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055047 ! LEUK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018476 name: LFDH_human def: "Putative guanine nucleotide exchange factor LFDH gene" [UniProtKB:Q008S8] synonym: "C6orf91" EXACT [UniProtKB:Q008S8] xref: EMBL:AL121834 xref: EMBL:DQ904331 xref: HGNC:HGNC:21093 xref: UniGene:Hs.660603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055682 ! LFDH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018477 name: LEFTY1_human def: "Left-right determination factor 1 precursor gene" [UniProtKB:O75610] synonym: "LEFTB" EXACT [UniProtKB:O75610] synonym: "LEFTYB" EXACT [UniProtKB:O75610] synonym: "UNQ278/PRO317" EXACT [UniProtKB:O75610] xref: EMBL:AF081504 xref: EMBL:AF081505 xref: EMBL:AF081506 xref: EMBL:AF081507 xref: EMBL:AF081512 xref: EMBL:AK222714 xref: EMBL:AL117348 xref: EMBL:AY358873 xref: EMBL:BC027883 xref: HGNC:HGNC:6552 xref: UniGene:Hs.656214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054657 ! LFTY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018478 name: LEFTY2_human def: "Left-right determination factor 2 precursor gene" [UniProtKB:O00292] synonym: "EBAF" EXACT [UniProtKB:O00292] synonym: "LEFTA" EXACT [UniProtKB:O00292] synonym: "LEFTYA" EXACT [UniProtKB:O00292] synonym: "PSEC0024" EXACT [UniProtKB:O00292] synonym: "TGFB4" EXACT [UniProtKB:O00292] xref: EMBL:AF081508 xref: EMBL:AF081509 xref: EMBL:AF081510 xref: EMBL:AF081511 xref: EMBL:AF081513 xref: EMBL:AK075344 xref: EMBL:AL117348 xref: EMBL:BC035718 xref: EMBL:U81523 xref: HGNC:HGNC:3122 xref: UniGene:Hs.520187 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054308 ! LFTY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018479 name: LGALS3BP_human def: "Galectin-3-binding protein precursor gene" [UniProtKB:Q08380] synonym: "M2BP" EXACT [UniProtKB:Q08380] xref: EMBL:BC002403 xref: EMBL:BC002998 xref: EMBL:BC015761 xref: EMBL:L13210 xref: EMBL:X79089 xref: HGNC:HGNC:6564 xref: UniGene:Hs.514535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055789 ! LG3BP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018480 name: LGI1_human def: "Leucine-rich glioma-inactivated protein 1 precursor gene" [UniProtKB:O95970] synonym: "EPT" EXACT [UniProtKB:O95970] synonym: "UNQ775/PRO1569" EXACT [UniProtKB:O95970] xref: EMBL:AF055636 xref: EMBL:AF473548 xref: EMBL:AL157396 xref: EMBL:AL358154 xref: EMBL:AY358885 xref: EMBL:BC022500 xref: HGNC:HGNC:6572 xref: UniGene:Hs.533670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054810 ! LGI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018481 name: LGR4_human def: "Leucine-rich repeat-containing G-protein coupled receptor 4 precursor gene" [UniProtKB:Q9BXB1] synonym: "GPR48" EXACT [UniProtKB:Q9BXB1] xref: EMBL:AC090597 xref: EMBL:AF257182 xref: EMBL:AF346709 xref: EMBL:AF346710 xref: EMBL:AF346711 xref: EMBL:BC033039 xref: EMBL:CH471064 xref: HGNC:HGNC:13299 xref: UniGene:Hs.502176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057469 ! Q8N537_HUMAN relationship: codes_for CCO:B0058548 ! LGR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018482 name: LGR5_human def: "Leucine-rich repeat-containing G-protein coupled receptor 5 precursor gene" [UniProtKB:O75473] synonym: "GPR49" EXACT [UniProtKB:O75473] synonym: "GPR67" EXACT [UniProtKB:O75473] xref: EMBL:AF061444 xref: EMBL:AF062006 xref: EMBL:BC096324 xref: EMBL:BC099650 xref: HGNC:HGNC:4504 xref: UniGene:Hs.658889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054640 ! LGR5_HUMAN relationship: codes_for CCO:B0056328 ! Q4VAM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018483 name: LGR6_human def: "Leucine-rich repeat-containing G-protein coupled receptor 6 precursor gene" [UniProtKB:Q9HBX8] synonym: "UNQ6427/PRO21331" EXACT [UniProtKB:Q9HBX8] synonym: "VTS20631" EXACT [UniProtKB:Q9HBX8] xref: EMBL:AB049405 xref: EMBL:AB083616 xref: EMBL:AF190501 xref: EMBL:AK027377 xref: EMBL:AL356953 xref: EMBL:AY358119 xref: EMBL:BC047905 xref: HGNC:HGNC:19719 xref: UniGene:Hs.497402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054022 ! A8MT74_HUMAN relationship: codes_for CCO:B0058794 ! LGR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018484 name: GLO1_human def: "Lactoylglutathione lyase gene" [UniProtKB:Q04760] xref: EMBL:AF146651 xref: EMBL:AL391415 xref: EMBL:BC001741 xref: EMBL:BC011365 xref: EMBL:BC015934 xref: EMBL:BT019987 xref: EMBL:BT019988 xref: EMBL:D13315 xref: EMBL:L07837 xref: EMBL:S83285 xref: HGNC:HGNC:4323 xref: UniGene:Hs.268849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055735 ! LGUL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018485 name: LHX1_human def: "LIM/homeobox protein Lhx1 gene" [UniProtKB:P48742] synonym: "LIM-1" EXACT [UniProtKB:P48742] synonym: "LIM1" EXACT [UniProtKB:P48742] xref: EMBL:AC023315 xref: EMBL:AC025882 xref: EMBL:BC101674 xref: EMBL:BC111936 xref: EMBL:U14755 xref: HGNC:HGNC:6593 xref: UniGene:Hs.443727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055411 ! LHX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018486 name: LHX2_human def: "LIM/homeobox protein Lhx2 gene" [UniProtKB:P50458] synonym: "LH2" EXACT [UniProtKB:P50458] xref: EMBL:AF124735 xref: EMBL:AK094511 xref: EMBL:BC093662 xref: EMBL:BC112185 xref: EMBL:U11701 xref: HGNC:HGNC:6594 xref: UniGene:Hs.696425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055451 ! LHX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018487 name: LHX3_human def: "LIM/homeobox protein Lhx3 gene" [UniProtKB:Q9UBR4] xref: EMBL:AF096165 xref: EMBL:AF096166 xref: EMBL:AF096167 xref: EMBL:AF096168 xref: EMBL:AF096169 xref: EMBL:AF156888 xref: EMBL:AF156889 xref: EMBL:AF211944 xref: EMBL:AF211946 xref: EMBL:AF211947 xref: EMBL:AF211948 xref: EMBL:AF211950 xref: EMBL:AF214637 xref: EMBL:AF367085 xref: EMBL:AF367086 xref: EMBL:AF367087 xref: EMBL:AF367088 xref: EMBL:AF367089 xref: HGNC:HGNC:6595 xref: UniGene:Hs.148427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029482 ! LHX3_HUMAN relationship: codes_for CCO:B0029488 ! Q9HBU2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018488 name: LHX5_human def: "LIM/homeobox protein Lhx5 gene" [UniProtKB:Q9H2C1] xref: EMBL:AF291181 xref: EMBL:BC109230 xref: HGNC:HGNC:14216 xref: UniGene:Hs.302029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058680 ! LHX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018489 name: LHX6_human def: "LIM/homeobox protein Lhx6.1 gene" [UniProtKB:Q9UPM6] synonym: "LHX6.1" EXACT [UniProtKB:Q9UPM6] xref: EMBL:AB031041 xref: EMBL:AB031042 xref: EMBL:AL136570 xref: EMBL:AL162424 xref: EMBL:BC103936 xref: EMBL:BC103937 xref: EMBL:CH471090 xref: HGNC:HGNC:21735 xref: UniGene:Hs.103137 xref: UniGene:Hs.699073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053926 ! A6PVQ1_HUMAN relationship: codes_for CCO:B0053927 ! A6PVQ2_HUMAN relationship: codes_for CCO:B0056594 ! Q5T7S7_HUMAN relationship: codes_for CCO:B0059261 ! LHX61_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018490 name: LHX8_human def: "LIM/homeobox protein Lhx8 gene" [UniProtKB:Q68G74] xref: EMBL:BC040321 xref: HGNC:HGNC:28838 xref: UniGene:Hs.403934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056710 ! LHX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018491 name: LHX9_human def: "LIM/homeobox protein Lhx9 gene" [UniProtKB:Q9NQ69] xref: EMBL:AJ277915 xref: EMBL:AJ277916 xref: EMBL:AJ277917 xref: EMBL:AJ277918 xref: EMBL:AJ277919 xref: EMBL:AJ277920 xref: EMBL:AJ296272 xref: EMBL:AL590115 xref: EMBL:AY273889 xref: EMBL:BC131622 xref: EMBL:CH471067 xref: HGNC:HGNC:14222 xref: UniGene:Hs.442578 xref: UniGene:Hs.706475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056653 ! Q5VUE2_HUMAN relationship: codes_for CCO:B0056654 ! Q5VUE6_HUMAN relationship: codes_for CCO:B0057248 ! Q86UH2_HUMAN relationship: codes_for CCO:B0058863 ! LHX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018492 name: LIFR_human def: "Leukemia inhibitory factor receptor precursor gene" [UniProtKB:P42702] xref: EMBL:U66563 xref: EMBL:X61615 xref: HGNC:HGNC:6597 xref: UniGene:Hs.133421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055355 ! LIFR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018493 name: LIF_human def: "Leukemia inhibitory factor precursor gene" [UniProtKB:P15018] synonym: "HILDA" EXACT [UniProtKB:P15018] xref: EMBL:AC004264 xref: EMBL:BC069540 xref: EMBL:BC093733 xref: EMBL:BC093735 xref: EMBL:J03261 xref: EMBL:M27052 xref: EMBL:M27053 xref: EMBL:M63420 xref: EMBL:X13967 xref: HGNC:HGNC:6596 xref: UniGene:Hs.2250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055030 ! LIF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018494 name: LIMA1_human def: "LIM domain and actin-binding protein 1 gene" [UniProtKB:Q9UHB6] synonym: "EPLIN" EXACT [UniProtKB:Q9UHB6] synonym: "PP624" EXACT [UniProtKB:Q9UHB6] synonym: "SREBP3" EXACT [UniProtKB:Q9UHB6] xref: EMBL:AF157325 xref: EMBL:AF198454 xref: EMBL:AF198455 xref: EMBL:AF218025 xref: EMBL:AK000057 xref: EMBL:AK000335 xref: EMBL:AK000372 xref: EMBL:AK023649 xref: EMBL:AL136911 xref: EMBL:BC001247 xref: EMBL:BC010664 xref: EMBL:BC110815 xref: HGNC:HGNC:24636 xref: UniGene:Hs.525419 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059132 ! LIMA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018495 name: LILRA1_human def: "Leukocyte immunoglobulin-like receptor subfamily A member 1 precursor gene" [UniProtKB:O75019] synonym: "LIR6" EXACT [UniProtKB:O75019] xref: EMBL:AF025529 xref: EMBL:AF025530 xref: EMBL:BC101514 xref: HGNC:HGNC:6602 xref: UniGene:Hs.667388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054592 ! LIRA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018496 name: LILRA2_human def: "Leukocyte immunoglobulin-like receptor subfamily A member 2 precursor gene" [UniProtKB:Q8N149] synonym: "ILT1" EXACT [UniProtKB:Q8N149] synonym: "LIR7" EXACT [UniProtKB:Q8N149] xref: EMBL:AF025531 xref: EMBL:BC017412 xref: EMBL:BC027916 xref: HGNC:HGNC:6603 xref: UniGene:Hs.655593 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057423 ! LIRA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018497 name: LILRA3_human def: "Leukocyte immunoglobulin-like receptor subfamily A member 3 precursor gene" [UniProtKB:Q8N6C8] synonym: "ILT6" EXACT [UniProtKB:Q8N6C8] synonym: "LIR4" EXACT [UniProtKB:Q8N6C8] xref: EMBL:AF025527 xref: EMBL:AF482762 xref: EMBL:AF482763 xref: EMBL:AF482764 xref: EMBL:AF482765 xref: EMBL:AF482766 xref: EMBL:AF482767 xref: EMBL:AF482768 xref: EMBL:AF482769 xref: EMBL:BC028208 xref: EMBL:U91926 xref: EMBL:U91927 xref: HGNC:HGNC:6604 xref: UniGene:Hs.113277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057487 ! LIRA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018498 name: LILRB2_human def: "Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor gene" [UniProtKB:Q8N423] synonym: "ILT4" EXACT [UniProtKB:Q8N423] synonym: "LIR2" EXACT [UniProtKB:Q8N423] synonym: "MIR10" EXACT [UniProtKB:Q8N423] xref: EMBL:AC010518 xref: EMBL:AF025528 xref: EMBL:AF283986 xref: EMBL:AF283987 xref: EMBL:BC036827 xref: HGNC:HGNC:6606 xref: UniGene:Hs.655652 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057459 ! LIRB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018499 name: LILRB3_human def: "Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor gene" [UniProtKB:O75022] synonym: "ILT5" EXACT [UniProtKB:O75022] synonym: "LIR3" EXACT [UniProtKB:O75022] xref: EMBL:AF025533 xref: EMBL:AF256195 xref: EMBL:U91928 xref: HGNC:HGNC:6607 xref: UniGene:Hs.631592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054593 ! LIRB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018500 name: LILRB4_human def: "Leukocyte immunoglobulin-like receptor subfamily B member 4 precursor gene" [UniProtKB:Q8NHJ6] synonym: "ILT3" EXACT [UniProtKB:Q8NHJ6] synonym: "LIR5" EXACT [UniProtKB:Q8NHJ6] xref: EMBL:AF025532 xref: EMBL:AF189768 xref: EMBL:AF283988 xref: EMBL:BC026309 xref: EMBL:U91925 xref: HGNC:HGNC:6608 xref: UniGene:Hs.67846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057875 ! LIRB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018501 name: LILRB5_human def: "Leukocyte immunoglobulin-like receptor subfamily B member 5 precursor gene" [UniProtKB:O75023] synonym: "LIR8" EXACT [UniProtKB:O75023] xref: EMBL:AF025534 xref: EMBL:AK057072 xref: EMBL:BC025704 xref: HGNC:HGNC:6609 xref: UniGene:Hs.655338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054594 ! LIRB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018502 name: LITAF_human def: "Lipopolysaccharide-induced tumor necrosis factor-alpha factor gene" [UniProtKB:Q99732] synonym: "PIG7" EXACT [UniProtKB:Q99732] synonym: "SIMPLE" EXACT [UniProtKB:Q99732] xref: EMBL:AB034747 xref: EMBL:AF010312 xref: EMBL:BC000053 xref: EMBL:BC008309 xref: EMBL:BC016491 xref: EMBL:BC039840 xref: EMBL:BC046154 xref: EMBL:BC096063 xref: EMBL:BC096065 xref: EMBL:BC096066 xref: EMBL:BC101401 xref: EMBL:BC101402 xref: EMBL:BC101969 xref: EMBL:BX537543 xref: EMBL:U77396 xref: HGNC:HGNC:16841 xref: UniGene:Hs.459940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058449 ! LITAF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018503 name: C16orf5_human def: "LITAF-like protein gene" [UniProtKB:Q9H305] synonym: "CDIP" EXACT [UniProtKB:Q9H305] xref: EMBL:AF131218 xref: EMBL:AF195661 xref: EMBL:AL136698 xref: EMBL:AL833853 xref: EMBL:BC002882 xref: EMBL:BC007604 xref: EMBL:CR533446 xref: EMBL:DQ167023 xref: HGNC:HGNC:13234 xref: UniGene:Hs.654653 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058693 ! LITFL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018504 name: L3MBTL_human def: "Lethal(3)malignant brain tumor-like protein gene" [UniProtKB:Q9Y468] synonym: "KIAA0681" EXACT [UniProtKB:Q9Y468] synonym: "L3MBT" EXACT [UniProtKB:Q9Y468] synonym: "L3MBTL1" EXACT [UniProtKB:Q9Y468] xref: EMBL:AB014581 xref: EMBL:AL031681 xref: EMBL:AL110279 xref: EMBL:BC039820 xref: EMBL:U89358 xref: EMBL:Z98752 xref: HGNC:HGNC:15905 xref: UniGene:Hs.300863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056432 ! Q5H8Y7_HUMAN relationship: codes_for CCO:B0056433 ! Q5H8Y9_HUMAN relationship: codes_for CCO:B0059352 ! LMBL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018505 name: L3MBTL2_human def: "Lethal(3)malignant brain tumor-like 2 protein gene" [UniProtKB:Q969R5] xref: EMBL:AJ305226 xref: EMBL:AJ305227 xref: EMBL:AK074091 xref: EMBL:AK097052 xref: EMBL:AL035658 xref: EMBL:AL035681 xref: EMBL:AL136564 xref: EMBL:BC017191 xref: EMBL:CR456482 xref: HGNC:HGNC:18594 xref: UniGene:Hs.517641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054170 ! B0QYT0_HUMAN relationship: codes_for CCO:B0058140 ! LMBL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018506 name: L3MBTL3_human def: "Lethal(3)malignant brain tumor-like 3 protein gene" [UniProtKB:Q96JM7] synonym: "KIAA1798" EXACT [UniProtKB:Q96JM7] xref: EMBL:AB058701 xref: EMBL:AL355581 xref: EMBL:AL583846 xref: EMBL:BC060845 xref: HGNC:HGNC:23035 xref: UniGene:Hs.658051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058245 ! LMBL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018507 name: L3MBTL4_human def: "Lethal(3)malignant brain tumor-like 4 protein gene" [UniProtKB:Q8NA19] xref: EMBL:AK093255 xref: EMBL:AP001021 xref: EMBL:BC039316 xref: EMBL:CH471113 xref: HGNC:HGNC:26677 xref: UniGene:Hs.128279 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054016 ! A8MSX5_HUMAN relationship: codes_for CCO:B0054030 ! A8MTL8_HUMAN relationship: codes_for CCO:B0057542 ! LMBL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018508 name: LMCD1_human def: "LIM and cysteine-rich domains protein 1 gene" [UniProtKB:Q9NZU5] xref: EMBL:AF169284 xref: EMBL:AF216709 xref: EMBL:AK022176 xref: EMBL:BC000646 xref: HGNC:HGNC:6633 xref: UniGene:Hs.475353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059018 ! LMCD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018509 name: LMO3_human def: "LIM domain only protein 3 gene" [UniProtKB:Q8TAP4] synonym: "RBTN3" EXACT [UniProtKB:Q8TAP4] synonym: "RBTNL2" EXACT [UniProtKB:Q8TAP4] synonym: "RHOM3" EXACT [UniProtKB:Q8TAP4] xref: EMBL:AK095595 xref: EMBL:BC026311 xref: HGNC:HGNC:6643 xref: UniGene:Hs.504908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057890 ! LMO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018510 name: LMO4_human def: "LIM domain transcription factor LMO4 gene" [UniProtKB:P61968] xref: EMBL:BC003600 xref: EMBL:BC017673 xref: EMBL:BC065818 xref: EMBL:U24576 xref: HGNC:HGNC:6644 xref: UniGene:Hs.436792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029479 ! LMO4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018511 name: LMX1A_human def: "LIM homeobox transcription factor 1-alpha gene" [UniProtKB:Q8TE12] xref: EMBL:AL160058 xref: EMBL:AL390730 xref: EMBL:AY078391 xref: EMBL:AY078392 xref: EMBL:AY078393 xref: EMBL:AY078394 xref: EMBL:AY078395 xref: EMBL:AY078396 xref: EMBL:AY078397 xref: EMBL:AY078398 xref: HGNC:HGNC:6653 xref: UniGene:Hs.667312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057949 ! LMX1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018512 name: LMX1B_human def: "LIM homeobox transcription factor 1-beta gene" [UniProtKB:O60663] xref: EMBL:AF057135 xref: EMBL:AF059572 xref: EMBL:AF059573 xref: EMBL:AF059574 xref: EMBL:AF059575 xref: EMBL:AL161731 xref: EMBL:AL161908 xref: EMBL:BC069601 xref: EMBL:BC112120 xref: EMBL:BC113491 xref: EMBL:CH471090 xref: HGNC:HGNC:6654 xref: UniGene:Hs.133709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054572 ! LMX1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018513 name: LIN28_human def: "Lin-28 homolog A gene" [UniProtKB:Q9H9Z2] synonym: "CSDD1" EXACT [UniProtKB:Q9H9Z2] synonym: "LIN28A" EXACT [UniProtKB:Q9H9Z2] synonym: "ZCCHC1" EXACT [UniProtKB:Q9H9Z2] xref: EMBL:AF521099 xref: EMBL:AK022519 xref: EMBL:AL513365 xref: EMBL:BC028566 xref: HGNC:HGNC:15986 xref: UniGene:Hs.86154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058758 ! LN28A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018514 name: LIN28B_human def: "Lin-28 homolog B gene" [UniProtKB:Q6ZN17] synonym: "CSDD2" EXACT [UniProtKB:Q6ZN17] xref: EMBL:AK131411 xref: EMBL:AL135911 xref: EMBL:BC127712 xref: EMBL:BC127713 xref: EMBL:BC141960 xref: EMBL:DQ127228 xref: EMBL:Z95329 xref: HGNC:HGNC:32207 xref: UniGene:Hs.23616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057005 ! LN28B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018515 name: ALOX12_human def: "Arachidonate 12-lipoxygenase, 12S-type gene" [UniProtKB:P18054] synonym: "LOG12" EXACT [UniProtKB:P18054] xref: EMBL:AF143883 xref: EMBL:AY527817 xref: EMBL:BC069557 xref: EMBL:D12638 xref: EMBL:M35418 xref: EMBL:M58704 xref: EMBL:M62982 xref: EMBL:M87004 xref: EMBL:S68587 xref: HGNC:HGNC:429 xref: UniGene:Hs.654431 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055097 ! LOX12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018516 name: LPHN1_human def: "Latrophilin-1 precursor gene" [UniProtKB:O94910] synonym: "KIAA0821" EXACT [UniProtKB:O94910] synonym: "LEC2" EXACT [UniProtKB:O94910] xref: EMBL:AB020628 xref: EMBL:AB065919 xref: EMBL:AF307079 xref: EMBL:BC002974 xref: EMBL:BC007587 xref: HGNC:HGNC:20973 xref: UniGene:Hs.654658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054710 ! LPHN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018517 name: LPHN2_human def: "Latrophilin-2 precursor gene" [UniProtKB:O95490] synonym: "KIAA0786" EXACT [UniProtKB:O95490] synonym: "LEC1" EXACT [UniProtKB:O95490] synonym: "LPHH1" EXACT [UniProtKB:O95490] xref: EMBL:AB018329 xref: EMBL:AC093154 xref: EMBL:AC113949 xref: EMBL:AF104266 xref: EMBL:AF104938 xref: EMBL:AF104939 xref: EMBL:AJ131581 xref: EMBL:AJ244492 xref: EMBL:AJ244493 xref: EMBL:AJ244494 xref: EMBL:AJ244496 xref: EMBL:AJ244497 xref: EMBL:AJ244498 xref: EMBL:AJ244499 xref: EMBL:AJ244501 xref: EMBL:AJ244502 xref: EMBL:AJ244503 xref: EMBL:AJ244504 xref: EMBL:AJ244505 xref: EMBL:AJ244506 xref: EMBL:AJ244507 xref: EMBL:AJ244510 xref: EMBL:AJ244511 xref: EMBL:AJ244512 xref: EMBL:AJ244516 xref: EMBL:AL157903 xref: EMBL:AL359705 xref: EMBL:CH471059 xref: HGNC:HGNC:18582 xref: UniGene:Hs.24212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053800 ! A6NE11_HUMAN relationship: codes_for CCO:B0054241 ! B1ALU1_HUMAN relationship: codes_for CCO:B0054242 ! B1ALU2_HUMAN relationship: codes_for CCO:B0054243 ! B1ALU3_HUMAN relationship: codes_for CCO:B0054244 ! B1ALU4_HUMAN relationship: codes_for CCO:B0054245 ! B1ALU5_HUMAN relationship: codes_for CCO:B0054246 ! B1ALU6_HUMAN relationship: codes_for CCO:B0054767 ! LPHN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018518 name: LPHN3_human def: "Latrophilin-3 precursor gene" [UniProtKB:Q9HAR2] synonym: "KIAA0768" EXACT [UniProtKB:Q9HAR2] synonym: "LEC3" EXACT [UniProtKB:Q9HAR2] xref: EMBL:AB018311 xref: EMBL:AF307080 xref: EMBL:AK000781 xref: HGNC:HGNC:20974 xref: UniGene:Hs.28391 xref: UniGene:Hs.694758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058766 ! LPHN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018519 name: PPAP2A_human def: "Lipid phosphate phosphohydrolase 1 gene" [UniProtKB:O14494] synonym: "LPP1" EXACT [UniProtKB:O14494] xref: EMBL:AB000888 xref: EMBL:AF014402 xref: EMBL:AF014403 xref: EMBL:AF017116 xref: EMBL:BC039847 xref: EMBL:BC117133 xref: EMBL:Y14436 xref: HGNC:HGNC:9228 xref: UniGene:Hs.696231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054344 ! LPP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018520 name: LRCH4_human def: "Leucine-rich repeat and calponin homology domain-containing protein 4 gene" [UniProtKB:O75427] synonym: "LRN" EXACT [UniProtKB:O75427] synonym: "LRRN1" EXACT [UniProtKB:O75427] synonym: "LRRN4" EXACT [UniProtKB:O75427] xref: EMBL:AF053356 xref: EMBL:BC007634 xref: EMBL:BC018529 xref: HGNC:HGNC:6691 xref: UniGene:Hs.125742 xref: UniGene:Hs.633863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054634 ! LRCH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018521 name: LRP12_human def: "Low-density lipoprotein receptor-related protein 12 precursor gene" [UniProtKB:Q9Y561] synonym: "ST7" EXACT [UniProtKB:Q9Y561] xref: EMBL:AF166350 xref: EMBL:BC032109 xref: HGNC:HGNC:31708 xref: UniGene:Hs.654804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059369 ! LRP12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018522 name: LRRK1_human def: "Leucine-rich repeat serine/threonine-protein kinase 1 gene" [UniProtKB:Q38SD2] synonym: "KIAA1790" EXACT [UniProtKB:Q38SD2] xref: EMBL:AB058693 xref: EMBL:AC090907 xref: EMBL:AK026772 xref: EMBL:AK130975 xref: EMBL:AK131075 xref: EMBL:BC066655 xref: EMBL:BC068080 xref: EMBL:DQ013130 xref: HGNC:HGNC:18608 xref: UniGene:Hs.407918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056243 ! LRRK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018523 name: LRRK2_human def: "Leucine-rich repeat serine/threonine-protein kinase 2 gene" [UniProtKB:Q5S007] synonym: "PARK8" EXACT [UniProtKB:Q5S007] xref: EMBL:AK127729 xref: EMBL:AL834529 xref: EMBL:AY792511 xref: HGNC:HGNC:18618 xref: UniGene:Hs.187636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056531 ! LRRK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018524 name: LHB_human def: "Lutropin subunit beta precursor gene" [UniProtKB:P01229] xref: EMBL:S71273 xref: EMBL:X00264 xref: HGNC:HGNC:6584 xref: UniGene:Hs.154704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054840 ! LSHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018525 name: LHCGR_human def: "Lutropin-choriogonadotropic hormone receptor precursor gene" [UniProtKB:P22888] synonym: "LCGR" EXACT [UniProtKB:P22888] synonym: "LGR2" EXACT [UniProtKB:P22888] synonym: "LHRHR" EXACT [UniProtKB:P22888] xref: EMBL:AF024642 xref: EMBL:AF082076 xref: EMBL:M63108 xref: EMBL:M73746 xref: EMBL:S57793 xref: EMBL:X84753 xref: EMBL:X84754 xref: EMBL:X84755 xref: EMBL:X84756 xref: EMBL:X84757 xref: EMBL:X84758 xref: EMBL:X84759 xref: EMBL:X84760 xref: EMBL:X84761 xref: EMBL:X84762 xref: EMBL:X84763 xref: HGNC:HGNC:6585 xref: UniGene:Hs.468490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055152 ! LSHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018526 name: LSP1_human def: "Lymphocyte-specific protein 1 gene" [UniProtKB:P33241] synonym: "WP34" EXACT [UniProtKB:P33241] xref: EMBL:AF043107 xref: EMBL:AF043348 xref: EMBL:AF043349 xref: EMBL:AF043350 xref: EMBL:BC001785 xref: EMBL:M33552 xref: EMBL:S67783 xref: EMBL:X55188 xref: HGNC:HGNC:6707 xref: UniGene:Hs.56729 xref: UniGene:Hs.656760 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054507 ! O43649_HUMAN relationship: codes_for CCO:B0055265 ! LSP1_HUMAN relationship: codes_for CCO:B0056125 ! Q16003_HUMAN relationship: codes_for CCO:B0059111 ! Q9UEV7_HUMAN relationship: codes_for CCO:B0059112 ! Q9UEV8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018527 name: LST1_human def: "Leukocyte-specific transcript 1 protein gene" [UniProtKB:O00453] synonym: "B144" EXACT [UniProtKB:O00453] xref: EMBL:AF000424 xref: EMBL:AF000425 xref: EMBL:AF000426 xref: EMBL:AF129756 xref: EMBL:AL662801 xref: EMBL:AL662847 xref: EMBL:AL929587 xref: EMBL:BA000025 xref: EMBL:BX248519 xref: EMBL:BX927320 xref: EMBL:CH471081 xref: EMBL:CR753892 xref: EMBL:CR759886 xref: EMBL:CR942185 xref: EMBL:U00921 xref: EMBL:Y18486 xref: EMBL:Y18487 xref: EMBL:Y18488 xref: EMBL:Y18489 xref: EMBL:Y18490 xref: HGNC:HGNC:14189 xref: UniGene:Hs.436066 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054322 ! LST1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018528 name: LTB4R_human def: "Leukotriene B4 receptor 1 gene" [UniProtKB:Q15722] synonym: "BLT" EXACT [UniProtKB:Q15722] synonym: "BLT1" EXACT [UniProtKB:Q15722] synonym: "BLTR" EXACT [UniProtKB:Q15722] synonym: "CMKRL1" EXACT [UniProtKB:Q15722] synonym: "GPR16" EXACT [UniProtKB:Q15722] synonym: "P2RY7" EXACT [UniProtKB:Q15722] xref: EMBL:AB008193 xref: EMBL:AY322535 xref: EMBL:BC004545 xref: EMBL:D89078 xref: EMBL:D89079 xref: EMBL:U33448 xref: EMBL:U41070 xref: EMBL:X98356 xref: HGNC:HGNC:6713 xref: UniGene:Hs.655431 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056100 ! LT4R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018529 name: LTB4R2_human def: "Leukotriene B4 receptor 2 gene" [UniProtKB:Q9NPC1] synonym: "BLT2R" EXACT [UniProtKB:Q9NPC1] synonym: "BLTR2" EXACT [UniProtKB:Q9NPC1] xref: EMBL:AB008193 xref: EMBL:AB029892 xref: EMBL:AB044402 xref: EMBL:AB083604 xref: EMBL:AF277230 xref: EMBL:AF308571 xref: EMBL:AJ278605 xref: EMBL:AY268433 xref: EMBL:BC119674 xref: EMBL:BC127643 xref: HGNC:HGNC:19260 xref: UniGene:Hs.642693 xref: UniGene:Hs.657595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053711 ! A1L156_HUMAN relationship: codes_for CCO:B0058846 ! LT4R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018530 name: LTBP4_human def: "Latent-transforming growth factor beta-binding protein 4 precursor gene" [UniProtKB:Q8N2S1] xref: EMBL:AC010412 xref: EMBL:AF051344 xref: EMBL:AF051345 xref: EMBL:AK074499 xref: EMBL:Y13622 xref: HGNC:HGNC:6717 xref: UniGene:Hs.466766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057449 ! LTBP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018531 name: BCAM_human def: "Lutheran blood group glycoprotein precursor gene" [UniProtKB:P50895] synonym: "LU" EXACT [UniProtKB:P50895] synonym: "MSK19" EXACT [UniProtKB:P50895] xref: EMBL:AY845133 xref: EMBL:BC050450 xref: EMBL:X80026 xref: EMBL:X83425 xref: HGNC:HGNC:6722 xref: UniGene:Hs.654540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055456 ! LU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018532 name: LY6E_human def: "Lymphocyte antigen 6E precursor gene" [UniProtKB:Q16553] synonym: "9804" EXACT [UniProtKB:Q16553] synonym: "RIGE" EXACT [UniProtKB:Q16553] synonym: "SCA2" EXACT [UniProtKB:Q16553] synonym: "TSA1" EXACT [UniProtKB:Q16553] xref: EMBL:BC119708 xref: EMBL:BC119709 xref: EMBL:U42376 xref: EMBL:U56145 xref: EMBL:U66711 xref: EMBL:Z68179 xref: HGNC:HGNC:6727 xref: UniGene:Hs.521903 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056149 ! LY6E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018533 name: LY86_human def: "Lymphocyte antigen 86 precursor gene" [UniProtKB:O95711] synonym: "MD1" EXACT [UniProtKB:O95711] xref: EMBL:AB020499 xref: EMBL:AF057178 xref: EMBL:AL031123 xref: EMBL:BC038846 xref: HGNC:HGNC:16837 xref: UniGene:Hs.653138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054784 ! LY86_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018534 name: LY96_human def: "Lymphocyte antigen 96 precursor gene" [UniProtKB:Q9Y6Y9] synonym: "ESOP1" EXACT [UniProtKB:Q9Y6Y9] synonym: "MD2" EXACT [UniProtKB:Q9Y6Y9] xref: EMBL:AB018549 xref: EMBL:AF168121 xref: EMBL:BC020690 xref: HGNC:HGNC:17156 xref: UniGene:Hs.660766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059423 ! LY96_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018535 name: LYL1_human def: "Protein lyl-1 gene" [UniProtKB:P12980] xref: EMBL:AC005546 xref: EMBL:BC002796 xref: EMBL:M22637 xref: EMBL:M22638 xref: HGNC:HGNC:6734 xref: UniGene:Hs.46446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055008 ! LYL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018536 name: LOX_human def: "Protein-lysine 6-oxidase precursor gene" [UniProtKB:P28300] xref: EMBL:AF039291 xref: EMBL:BC074820 xref: EMBL:BC074872 xref: EMBL:BC089436 xref: EMBL:L16895 xref: EMBL:M84150 xref: EMBL:M94054 xref: EMBL:S45875 xref: EMBL:S78694 xref: HGNC:HGNC:6664 xref: UniGene:Hs.102267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055199 ! LYOX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018537 name: LYST_human def: "Lysosomal-trafficking regulator gene" [UniProtKB:Q99698] synonym: "CHS" EXACT [UniProtKB:Q99698] synonym: "CHS1" EXACT [UniProtKB:Q99698] xref: EMBL:AL121997 xref: EMBL:AL390765 xref: EMBL:L77889 xref: EMBL:U67615 xref: EMBL:U70064 xref: EMBL:U72192 xref: EMBL:U84744 xref: HGNC:HGNC:1968 xref: UniGene:Hs.532411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058442 ! LYST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018538 name: MAP3K2_human def: "Mitogen-activated protein kinase kinase kinase 2 gene" [UniProtKB:Q9Y2U5] synonym: "MAPKKK2" EXACT [UniProtKB:Q9Y2U5] synonym: "MEKK2" EXACT [UniProtKB:Q9Y2U5] xref: EMBL:AB208963 xref: EMBL:AC068282 xref: EMBL:AC110926 xref: EMBL:AF111105 xref: EMBL:AF239798 xref: EMBL:AK075004 xref: HGNC:HGNC:6854 xref: UniGene:Hs.145605 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059318 ! M3K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018539 name: MAP3K6_human def: "Mitogen-activated protein kinase kinase kinase 6 gene" [UniProtKB:O95382] synonym: "ASK2" EXACT [UniProtKB:O95382] synonym: "MAPKKK6" EXACT [UniProtKB:O95382] synonym: "MEKK6" EXACT [UniProtKB:O95382] xref: EMBL:AB167411 xref: EMBL:AB208805 xref: EMBL:AF100318 xref: EMBL:AL663123 xref: EMBL:BC015914 xref: EMBL:BC129950 xref: EMBL:BC129951 xref: HGNC:HGNC:6858 xref: UniGene:Hs.194694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054754 ! M3K6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018540 name: MS4A10_human def: "Membrane-spanning 4-domains subfamily A member 10 gene" [UniProtKB:Q96PG2] xref: EMBL:AF354934 xref: EMBL:AF354935 xref: EMBL:AK122633 xref: HGNC:HGNC:13368 xref: UniGene:Hs.591956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058334 ! M4A10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018541 name: MS4A12_human def: "Membrane-spanning 4-domains subfamily A member 12 gene" [UniProtKB:Q9NXJ0] xref: EMBL:AK000224 xref: EMBL:BC029793 xref: HGNC:HGNC:13370 xref: UniGene:Hs.272789 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058954 ! M4A12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018542 name: MS4A13_human def: "Membrane-spanning 4-domains subfamily A member 13 gene" [UniProtKB:Q5J8X5] xref: EMBL:AY324188 xref: EMBL:AY324189 xref: EMBL:AY324190 xref: HGNC:HGNC:16674 xref: UniGene:Hs.523704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056449 ! M4A13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018543 name: MS4A14_human def: "Membrane-spanning 4-domains subfamily A member 14 gene" [UniProtKB:Q96JA4] synonym: "MS4A13" EXACT [UniProtKB:Q96JA4] xref: EMBL:AF367473 xref: EMBL:AL137391 xref: EMBL:AY094610 xref: EMBL:AY094611 xref: EMBL:AY584610 xref: EMBL:BC043485 xref: EMBL:BC107431 xref: HGNC:HGNC:30706 xref: UniGene:Hs.530735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058236 ! M4A14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018544 name: MS4A15_human def: "Membrane-spanning 4-domains subfamily A member 15 gene" [UniProtKB:Q8N5U1] xref: EMBL:AP004243 xref: EMBL:AY584609 xref: EMBL:BC031610 xref: EMBL:CH471076 xref: HGNC:HGNC:28573 xref: UniGene:Hs.207465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054155 ! A9UJY7_HUMAN relationship: codes_for CCO:B0057479 ! M4A15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018545 name: MS4A4A_human def: "Membrane-spanning 4-domains subfamily A member 4A gene" [UniProtKB:Q96JQ5] synonym: "4SPAN1" EXACT [UniProtKB:Q96JQ5] synonym: "CD20L1" EXACT [UniProtKB:Q96JQ5] synonym: "HDCME31P" EXACT [UniProtKB:Q96JQ5] synonym: "MS4A4" EXACT [UniProtKB:Q96JQ5] xref: EMBL:AB013102 xref: EMBL:AB022821 xref: EMBL:AF068288 xref: EMBL:AF237912 xref: EMBL:AF350500 xref: EMBL:AF354928 xref: EMBL:BC020648 xref: HGNC:HGNC:13371 xref: UniGene:Hs.325960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058248 ! M4A4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018546 name: MS4A4E_human def: "Putative membrane-spanning 4-domains subfamily A member 4E gene" [UniProtKB:Q96PG1] xref: EMBL:AB231725 xref: EMBL:AB231726 xref: EMBL:AB231727 xref: EMBL:AB231728 xref: EMBL:AF354936 xref: EMBL:DC379793 xref: HGNC:HGNC:14284 xref: UniGene:Hs.559934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058333 ! M4A4E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018547 name: MS4A6A_human def: "Membrane-spanning 4-domains subfamily A member 6A gene" [UniProtKB:Q9H2W1] synonym: "4SPAN3" EXACT [UniProtKB:Q9H2W1] synonym: "CD20L3" EXACT [UniProtKB:Q9H2W1] synonym: "CDA01" EXACT [UniProtKB:Q9H2W1] synonym: "MS4A6" EXACT [UniProtKB:Q9H2W1] xref: EMBL:AB013104 xref: EMBL:AF142409 xref: EMBL:AF212240 xref: EMBL:AF237908 xref: EMBL:AF253977 xref: EMBL:AF261136 xref: EMBL:AF286866 xref: EMBL:AF350502 xref: EMBL:AF350503 xref: EMBL:AF354930 xref: EMBL:BC022854 xref: HGNC:HGNC:13375 xref: UniGene:Hs.523702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058689 ! M4A6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018548 name: MS4A6E_human def: "Membrane-spanning 4-domains subfamily A member 6E gene" [UniProtKB:Q96DS6] xref: EMBL:AF333758 xref: EMBL:AF354931 xref: EMBL:AF354932 xref: EMBL:AF354933 xref: EMBL:BC034588 xref: EMBL:BC069322 xref: EMBL:BC101783 xref: HGNC:HGNC:14285 xref: UniGene:Hs.662211 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058196 ! M4A6E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018549 name: MS4A8B_human def: "Membrane-spanning 4-domains subfamily A member 8B gene" [UniProtKB:Q9BY19] synonym: "4SPAN4" EXACT [UniProtKB:Q9BY19] xref: EMBL:AF237905 xref: EMBL:AF350504 xref: EMBL:BC022895 xref: HGNC:HGNC:13380 xref: UniGene:Hs.150878 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058566 ! M4A8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018550 name: MAP4K1_human def: "Mitogen-activated protein kinase kinase kinase kinase 1 gene" [UniProtKB:Q92918] synonym: "HPK1" EXACT [UniProtKB:Q92918] xref: EMBL:U66464 xref: HGNC:HGNC:6863 xref: UniGene:Hs.95424 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058112 ! M4K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018551 name: MAP4K3_human def: "Mitogen-activated protein kinase kinase kinase kinase 3 gene" [UniProtKB:Q8IVH8] synonym: "RAB8IPL1" EXACT [UniProtKB:Q8IVH8] xref: EMBL:AC007684 xref: EMBL:AF000145 xref: EMBL:AF445385 xref: EMBL:AF445386 xref: EMBL:AF445387 xref: EMBL:AF445388 xref: EMBL:AF445390 xref: EMBL:AF445391 xref: EMBL:AF445392 xref: EMBL:AF445393 xref: EMBL:AF445394 xref: EMBL:AF445395 xref: EMBL:AF445396 xref: EMBL:AF445397 xref: EMBL:AF445398 xref: EMBL:AF445399 xref: EMBL:AF445400 xref: EMBL:AF445401 xref: EMBL:AF445402 xref: EMBL:AF445403 xref: EMBL:AF445404 xref: EMBL:AF445405 xref: EMBL:AF445406 xref: EMBL:AF445407 xref: EMBL:AF445408 xref: EMBL:AF445409 xref: EMBL:AF445410 xref: EMBL:AF445411 xref: EMBL:AF445412 xref: EMBL:AF445413 xref: HGNC:HGNC:6865 xref: UniGene:Hs.655750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057345 ! M4K3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018552 name: MAP4K5_human def: "Mitogen-activated protein kinase kinase kinase kinase 5 gene" [UniProtKB:Q9Y4K4] xref: EMBL:BC036013 xref: EMBL:U77129 xref: HGNC:HGNC:6867 xref: UniGene:Hs.130491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059365 ! M4K5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018553 name: MAP6D1_human def: "MAP6 domain-containing protein 1 gene" [UniProtKB:Q9H9H5] xref: EMBL:AK022810 xref: EMBL:BC006434 xref: HGNC:HGNC:25753 xref: UniGene:Hs.478465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058755 ! MA6D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018554 name: MXD1_human def: "MAD protein gene" [UniProtKB:Q05195] synonym: "MAD" EXACT [UniProtKB:Q05195] xref: EMBL:AC019206 xref: EMBL:BC069377 xref: EMBL:BC069433 xref: EMBL:BC098396 xref: EMBL:BC113531 xref: EMBL:BC117260 xref: EMBL:CR536495 xref: EMBL:CR541692 xref: EMBL:L06895 xref: HGNC:HGNC:6761 xref: UniGene:Hs.468908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015400 ! MAD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018555 name: MXD3_human def: "Max-interacting transcriptional repressor MAD3 gene" [UniProtKB:Q9BW11] synonym: "MAD3" EXACT [UniProtKB:Q9BW11] xref: EMBL:AF114834 xref: EMBL:AK057034 xref: EMBL:AK222579 xref: EMBL:AL833959 xref: EMBL:BC000745 xref: EMBL:BC032586 xref: HGNC:HGNC:14008 xref: UniGene:Hs.702195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055753 ! Q05BW2_HUMAN relationship: codes_for CCO:B0058529 ! MAD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018556 name: MXD4_human def: "Max-interacting transcriptional repressor MAD4 gene" [UniProtKB:Q14582] synonym: "MAD4" EXACT [UniProtKB:Q14582] xref: EMBL:AF040963 xref: EMBL:AF082740 xref: EMBL:AL158068 xref: EMBL:BC068060 xref: EMBL:BT019969 xref: EMBL:BT019970 xref: EMBL:Z49250 xref: HGNC:HGNC:13906 xref: UniGene:Hs.655020 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015399 ! MAD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018557 name: MADCAM1_human def: "Mucosal addressin cell adhesion molecule 1 precursor gene" [UniProtKB:Q13477] xref: EMBL:AC005775 xref: EMBL:U43628 xref: EMBL:U80012 xref: EMBL:U80013 xref: EMBL:U80014 xref: EMBL:U80015 xref: EMBL:U80016 xref: EMBL:U82483 xref: HGNC:HGNC:6765 xref: UniGene:Hs.102598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055912 ! MADCA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018558 name: NDNL2_human def: "Melanoma-associated antigen G1 gene" [UniProtKB:Q96MG7] synonym: "HCA4" EXACT [UniProtKB:Q96MG7] synonym: "MAGEG1" EXACT [UniProtKB:Q96MG7] xref: EMBL:AF320911 xref: EMBL:AF490510 xref: EMBL:AK056957 xref: EMBL:AK074138 xref: EMBL:BC041166 xref: EMBL:BC053999 xref: HGNC:HGNC:7677 xref: UniGene:Hs.656412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022490 ! MAGG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018559 name: MAGI1_human def: "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 gene" [UniProtKB:Q96QZ7] synonym: "BAIAP1" EXACT [UniProtKB:Q96QZ7] synonym: "BAP1" EXACT [UniProtKB:Q96QZ7] synonym: "TNRC19" EXACT [UniProtKB:Q96QZ7] xref: EMBL:AB010894 xref: EMBL:AF401654 xref: EMBL:AF401655 xref: EMBL:AF401656 xref: EMBL:AL357075 xref: EMBL:U80754 xref: EMBL:U96115 xref: HGNC:HGNC:946 xref: UniGene:Hs.651939 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056579 ! Q5T4Y8_HUMAN relationship: codes_for CCO:B0058358 ! MAGI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018560 name: MAK10_human def: "Protein MAK10 homolog gene" [UniProtKB:Q5VZE5] synonym: "EGAP" EXACT [UniProtKB:Q5VZE5] xref: EMBL:AK025266 xref: EMBL:AK026296 xref: EMBL:AL161447 xref: EMBL:AL161453 xref: EMBL:AL353743 xref: EMBL:BC117427 xref: EMBL:BC117429 xref: EMBL:CH471089 xref: HGNC:HGNC:24340 xref: UniGene:Hs.436098 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056675 ! MAK10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018561 name: MALT1_human def: "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 gene" [UniProtKB:Q9UDY8] synonym: "MLT" EXACT [UniProtKB:Q9UDY8] xref: EMBL:AB026118 xref: EMBL:AF130356 xref: EMBL:AF316597 xref: EMBL:AL137399 xref: EMBL:BC030143 xref: HGNC:HGNC:6819 xref: UniGene:Hs.601217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059106 ! MALT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018562 name: MAL_human def: "Myelin and lymphocyte protein gene" [UniProtKB:P21145] xref: EMBL:BC000458 xref: EMBL:BC003006 xref: EMBL:M15800 xref: EMBL:X76220 xref: EMBL:X76221 xref: EMBL:X76222 xref: EMBL:X76223 xref: EMBL:X76678 xref: EMBL:X76679 xref: EMBL:X76680 xref: EMBL:X76681 xref: HGNC:HGNC:6817 xref: UniGene:Hs.80395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055131 ! MAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018563 name: MAML1_human def: "Mastermind-like protein 1 gene" [UniProtKB:Q92585] synonym: "KIAA0200" EXACT [UniProtKB:Q92585] xref: EMBL:AF221759 xref: EMBL:D83785 xref: HGNC:HGNC:13632 xref: UniGene:Hs.631951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058068 ! MAML1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018564 name: MAML2_human def: "Mastermind-like protein 2 gene" [UniProtKB:Q8IZL2] synonym: "KIAA1819" EXACT [UniProtKB:Q8IZL2] xref: EMBL:AB058722 xref: EMBL:AY040322 xref: EMBL:AY040324 xref: EMBL:AY186997 xref: EMBL:AY186998 xref: EMBL:BC152449 xref: EMBL:CR627398 xref: HGNC:HGNC:16259 xref: UniGene:Hs.428214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057409 ! MAML2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018565 name: MAML3_human def: "Mastermind-like protein 3 gene" [UniProtKB:Q96JK9] synonym: "KIAA1816" EXACT [UniProtKB:Q96JK9] xref: EMBL:AB058719 xref: EMBL:AC097464 xref: EMBL:AC104798 xref: EMBL:AC108053 xref: EMBL:AC131182 xref: EMBL:AK123604 xref: EMBL:BC137130 xref: EMBL:BC137131 xref: EMBL:CH471056 xref: HGNC:HGNC:16272 xref: UniGene:Hs.586165 xref: UniGene:Hs.668459 xref: UniGene:Hs.705487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058242 ! MAML3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018566 name: MAP1B_human def: "Microtubule-associated protein 1B gene" [UniProtKB:P46821] xref: EMBL:L06237 xref: HGNC:HGNC:6836 xref: UniGene:Hs.637017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055380 ! MAP1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018567 name: MAP4_human def: "Microtubule-associated protein 4 gene" [UniProtKB:P27816] xref: EMBL:AB209377 xref: EMBL:AK054696 xref: EMBL:AK125245 xref: EMBL:BC008715 xref: EMBL:BC012794 xref: EMBL:BC015149 xref: EMBL:CH471055 xref: EMBL:CR749544 xref: EMBL:M64571 xref: EMBL:U19727 xref: HGNC:HGNC:6862 xref: UniGene:Hs.517949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055196 ! MAP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018568 name: MAPKAPK2_human def: "MAP kinase-activated protein kinase 2 gene" [UniProtKB:P49137] xref: EMBL:BC036060 xref: EMBL:BC052584 xref: EMBL:U12779 xref: EMBL:X75346 xref: HGNC:HGNC:6887 xref: UniGene:Hs.643566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055417 ! MAPK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018569 name: MAPKAPK3_human def: "MAP kinase-activated protein kinase 3 gene" [UniProtKB:Q16644] xref: EMBL:BC001662 xref: EMBL:BC007591 xref: EMBL:BC010407 xref: EMBL:U09578 xref: EMBL:U43784 xref: HGNC:HGNC:6888 xref: UniGene:Hs.234521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056166 ! MAPK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018570 name: MARCO_human def: "Macrophage receptor MARCO gene" [UniProtKB:Q9UEW3] synonym: "SCARA2" EXACT [UniProtKB:Q9UEW3] xref: EMBL:AF035819 xref: EMBL:AF128172 xref: EMBL:AF128173 xref: EMBL:AF128174 xref: EMBL:AF128175 xref: EMBL:AF128176 xref: EMBL:AF128177 xref: EMBL:AF128178 xref: EMBL:AF128179 xref: EMBL:AF128180 xref: EMBL:AF128181 xref: EMBL:AF128182 xref: EMBL:AF128183 xref: EMBL:AF128184 xref: EMBL:AF128185 xref: EMBL:AF128186 xref: EMBL:BC016004 xref: HGNC:HGNC:6895 xref: UniGene:Hs.67726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059113 ! MARCO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018571 name: MAS1L_human def: "Mas-related G-protein coupled receptor MRG gene" [UniProtKB:P35410] synonym: "MRG" EXACT [UniProtKB:P35410] xref: EMBL:AL035542 xref: EMBL:BC069127 xref: EMBL:BC069345 xref: EMBL:S78653 xref: HGNC:HGNC:13961 xref: UniGene:Hs.533297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055289 ! MAS1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018572 name: MASTR_human def: "MEF2-activating SAP transcriptional regulatory protein gene" [UniProtKB:Q6ZN01] xref: EMBL:AK093389 xref: EMBL:AK131427 xref: EMBL:BC105056 xref: EMBL:BC105058 xref: EMBL:BC106047 xref: EMBL:CH471177 xref: UniGene:Hs.191815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057000 ! MASTR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018573 name: MAS1_human def: "MAS proto-oncogene gene" [UniProtKB:P04201] synonym: "MAS" EXACT [UniProtKB:P04201] xref: EMBL:AL035691 xref: EMBL:BC069142 xref: EMBL:BC069581 xref: EMBL:BC110454 xref: EMBL:CR542261 xref: EMBL:M13150 xref: HGNC:HGNC:6899 xref: UniGene:Hs.99900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054888 ! MAS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018574 name: MAVS_human def: "Mitochondrial antiviral-signaling protein gene" [UniProtKB:Q7Z434] synonym: "IPS1" EXACT [UniProtKB:Q7Z434] synonym: "KIAA1271" EXACT [UniProtKB:Q7Z434] synonym: "VISA" EXACT [UniProtKB:Q7Z434] xref: EMBL:AB033097 xref: EMBL:AB097003 xref: EMBL:AK023799 xref: EMBL:AK123956 xref: EMBL:AK130992 xref: EMBL:AL109804 xref: EMBL:AL353194 xref: EMBL:BC044952 xref: EMBL:DQ167126 xref: EMBL:DQ174270 xref: EMBL:DQ181928 xref: UniGene:Hs.646283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057158 ! MAVS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018575 name: MAZ_human def: "Myc-associated zinc finger protein gene" [UniProtKB:P56270] xref: EMBL:AB017335 xref: EMBL:D85131 xref: EMBL:M93339 xref: EMBL:M94046 xref: EMBL:U33819 xref: HGNC:HGNC:6914 xref: UniGene:Hs.23650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055543 ! MAZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018576 name: MBD3L1_human def: "Methyl-CpG-binding domain protein 3-like 1 gene" [UniProtKB:Q8WWY6] synonym: "MBD3L" EXACT [UniProtKB:Q8WWY6] xref: EMBL:AY038022 xref: EMBL:BC112058 xref: EMBL:BC112064 xref: HGNC:HGNC:15774 xref: UniGene:Hs.133912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058008 ! MB3L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018577 name: MYBBP1A_human def: "Myb-binding protein 1A gene" [UniProtKB:Q9BQG0] synonym: "P160" EXACT [UniProtKB:Q9BQG0] xref: EMBL:AF147709 xref: EMBL:AL133098 xref: EMBL:AL136595 xref: EMBL:BC000641 xref: EMBL:BC050546 xref: HGNC:HGNC:7546 xref: UniGene:Hs.22824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058481 ! MBB1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018578 name: MBD2_human def: "Methyl-CpG-binding domain protein 2 gene" [UniProtKB:Q9UBB5] xref: EMBL:AF072242 xref: EMBL:AF072246 xref: EMBL:AF120988 xref: EMBL:AF120989 xref: EMBL:AF120990 xref: EMBL:AF120991 xref: EMBL:AF120992 xref: EMBL:AF120993 xref: EMBL:BC032638 xref: HGNC:HGNC:6917 xref: UniGene:Hs.25674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059065 ! MBD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018579 name: MBD3_human def: "Methyl-CpG-binding domain protein 3 gene" [UniProtKB:O95983] xref: EMBL:AC005943 xref: EMBL:AF072247 xref: EMBL:BC009372 xref: EMBL:BC009438 xref: EMBL:BC032443 xref: EMBL:BC043619 xref: HGNC:HGNC:6918 xref: UniGene:Hs.178728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054814 ! MBD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018580 name: MBTD1_human def: "MBT domain-containing protein 1 gene" [UniProtKB:Q05BQ5] xref: EMBL:AC005839 xref: EMBL:AC006141 xref: EMBL:AK000062 xref: EMBL:AK124061 xref: EMBL:BC034364 xref: EMBL:BC101736 xref: EMBL:CH471109 xref: HGNC:HGNC:19866 xref: UniGene:Hs.656803 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055750 ! MBTD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018581 name: EEF1E1_human def: "Eukaryotic translation elongation factor 1 epsilon-1 gene" [UniProtKB:O43324] synonym: "P18" EXACT [UniProtKB:O43324] xref: EMBL:AB011079 xref: EMBL:AF054186 xref: EMBL:AL023694 xref: EMBL:AL355499 xref: EMBL:AL451187 xref: EMBL:BC005291 xref: EMBL:BT007306 xref: HGNC:HGNC:3212 xref: UniGene:Hs.631818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054472 ! MCA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018582 name: ATF7IP_human def: "Activating transcription factor 7-interacting protein 1 gene" [UniProtKB:Q6VMQ6] synonym: "MCAF" EXACT [UniProtKB:Q6VMQ6] synonym: "MCAF1" EXACT [UniProtKB:Q6VMQ6] xref: EMBL:AC007782 xref: EMBL:AC008814 xref: EMBL:AC124892 xref: EMBL:AF425650 xref: EMBL:AJ242978 xref: EMBL:AK001001 xref: EMBL:AK001550 xref: EMBL:AY337596 xref: EMBL:BC037312 xref: EMBL:BC063855 xref: HGNC:HGNC:20092 xref: UniGene:Hs.591151 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056962 ! MCAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018583 name: ATF7IP2_human def: "Activating transcription factor 7-interacting protein 2 gene" [UniProtKB:Q5U623] synonym: "MCAF2" EXACT [UniProtKB:Q5U623] xref: EMBL:AK022730 xref: EMBL:AK093414 xref: EMBL:AK223492 xref: EMBL:AL832987 xref: EMBL:AY560615 xref: EMBL:BC033891 xref: EMBL:BC069695 xref: EMBL:BC069713 xref: EMBL:BC069730 xref: HGNC:HGNC:20397 xref: UniGene:Hs.513343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056638 ! MCAF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018584 name: SLC25A20_human def: "Mitochondrial carnitine/acylcarnitine carrier protein gene" [UniProtKB:O43772] synonym: "CAC" EXACT [UniProtKB:O43772] synonym: "CACT" EXACT [UniProtKB:O43772] xref: EMBL:BC001689 xref: EMBL:Y10319 xref: EMBL:Y17775 xref: EMBL:Y17776 xref: EMBL:Y17777 xref: EMBL:Y17778 xref: EMBL:Y17779 xref: HGNC:HGNC:1421 xref: UniGene:Hs.13845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054520 ! MCAT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018585 name: MCF2L_human def: "Guanine nucleotide exchange factor DBS gene" [UniProtKB:O15068] synonym: "KIAA0362" EXACT [UniProtKB:O15068] xref: EMBL:AB002360 xref: EMBL:AB116074 xref: EMBL:AB116075 xref: EMBL:AK123267 xref: EMBL:AL137002 xref: EMBL:AL162454 xref: EMBL:AL356740 xref: EMBL:AL596093 xref: EMBL:BC011853 xref: EMBL:BC020208 xref: HGNC:HGNC:14576 xref: UniGene:Hs.170422 xref: UniGene:Hs.597691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054403 ! MCF2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018586 name: MCF2_human def: "Proto-oncogene DBL gene" [UniProtKB:P10911] synonym: "DBL" EXACT [UniProtKB:P10911] xref: EMBL:AB085901 xref: EMBL:AB085902 xref: EMBL:AL033403 xref: EMBL:AL117234 xref: EMBL:AL161777 xref: EMBL:CH471150 xref: EMBL:J03639 xref: EMBL:X12556 xref: EMBL:X13230 xref: HGNC:HGNC:6940 xref: UniGene:Hs.387262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054981 ! MCF2_HUMAN relationship: codes_for CCO:B0056506 ! Q5JYJ2_HUMAN relationship: codes_for CCO:B0056507 ! Q5JYJ3_HUMAN relationship: codes_for CCO:B0056508 ! Q5JYJ5_HUMAN relationship: codes_for CCO:B0056509 ! Q5JYJ6_HUMAN relationship: codes_for CCO:B0056510 ! Q5JYJ7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018587 name: MCHR1_human def: "Melanin-concentrating hormone receptor 1 gene" [UniProtKB:Q99705] synonym: "GPR24" EXACT [UniProtKB:Q99705] synonym: "SLC1" EXACT [UniProtKB:Q99705] xref: EMBL:AB063174 xref: EMBL:AF490537 xref: EMBL:AY562945 xref: EMBL:BC001736 xref: EMBL:BC021146 xref: EMBL:BT006725 xref: EMBL:CR456497 xref: EMBL:U71092 xref: EMBL:Z86090 xref: HGNC:HGNC:4479 xref: UniGene:Hs.248122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058444 ! MCHR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018588 name: MCHR2_human def: "Melanin-concentrating hormone receptor 2 gene" [UniProtKB:Q969V1] synonym: "GPR145" EXACT [UniProtKB:Q969V1] synonym: "SLT" EXACT [UniProtKB:Q969V1] xref: EMBL:AB058849 xref: EMBL:AB060151 xref: EMBL:AF347063 xref: EMBL:AF399937 xref: EMBL:AL590725 xref: EMBL:AY029596 xref: EMBL:AY562946 xref: EMBL:BC095515 xref: HGNC:HGNC:20867 xref: UniGene:Hs.591342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058141 ! MCHR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018589 name: PMCH_human def: "Pro-MCH precursor gene" [UniProtKB:P20382] synonym: "MCH" EXACT [UniProtKB:P20382] xref: EMBL:M57703 xref: EMBL:S63697 xref: HGNC:HGNC:9109 xref: UniGene:Hs.705380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055120 ! MCH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018590 name: MCL1_human def: "Induced myeloid leukemia cell differentiation protein Mcl-1 gene" [UniProtKB:Q07820] xref: EMBL:AF118124 xref: EMBL:AF118276 xref: EMBL:AF118277 xref: EMBL:AF118278 xref: EMBL:AF147742 xref: EMBL:AF162676 xref: EMBL:AF162677 xref: EMBL:AF198614 xref: EMBL:AF203373 xref: EMBL:AL356356 xref: EMBL:BC017197 xref: EMBL:BC071897 xref: EMBL:BC107735 xref: EMBL:BT006640 xref: EMBL:DQ088966 xref: EMBL:L08246 xref: HGNC:HGNC:6943 xref: UniGene:Hs.632486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055785 ! MCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018591 name: MCM3AP_human def: "80 kDa MCM3-associated protein gene" [UniProtKB:O60318] synonym: "GANP" EXACT [UniProtKB:O60318] synonym: "KIAA0572" EXACT [UniProtKB:O60318] synonym: "MAP80" EXACT [UniProtKB:O60318] xref: EMBL:AB005543 xref: EMBL:AB011144 xref: EMBL:AJ010089 xref: EMBL:AY590469 xref: EMBL:BC104958 xref: EMBL:BC104960 xref: HGNC:HGNC:6946 xref: UniGene:Hs.389037 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054547 ! MCM3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018592 name: NR3C2_human def: "Mineralocorticoid receptor gene" [UniProtKB:P08235] synonym: "MCR" EXACT [UniProtKB:P08235] synonym: "MLR" EXACT [UniProtKB:P08235] xref: EMBL:AF068616 xref: EMBL:AF068617 xref: EMBL:AF068618 xref: EMBL:AF068619 xref: EMBL:AF068620 xref: EMBL:AF068621 xref: EMBL:AF068622 xref: EMBL:AF068623 xref: EMBL:AJ315514 xref: EMBL:AJ315515 xref: EMBL:BC111758 xref: EMBL:EU326312 xref: EMBL:M16801 xref: HGNC:HGNC:7979 xref: UniGene:Hs.163924 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054201 ! B0ZBF7_HUMAN relationship: codes_for CCO:B0054202 ! B0ZBF8_HUMAN relationship: codes_for CCO:B0054925 ! MCR_HUMAN relationship: codes_for CCO:B0056217 ! Q2NKL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018593 name: MCTP1_human def: "Multiple C2 and transmembrane domain-containing protein 1 gene" [UniProtKB:Q6DN14] xref: EMBL:AK025997 xref: EMBL:AK057694 xref: EMBL:AK091330 xref: EMBL:AY656715 xref: EMBL:AY656716 xref: EMBL:BC030005 xref: HGNC:HGNC:26183 xref: UniGene:Hs.655087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056727 ! MCTP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018594 name: MCTP2_human def: "Multiple C2 and transmembrane domain-containing protein 2 gene" [UniProtKB:Q6DN12] xref: EMBL:AK001953 xref: EMBL:AK002037 xref: EMBL:AY656717 xref: EMBL:BC025708 xref: EMBL:BC041387 xref: EMBL:BC111024 xref: EMBL:BC131527 xref: HGNC:HGNC:25636 xref: UniGene:Hs.592017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056726 ! MCTP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018595 name: MDFIC_human def: "MyoD family inhibitor domain-containing protein gene" [UniProtKB:Q9P1T7] xref: EMBL:AF054589 xref: EMBL:AY196485 xref: HGNC:HGNC:28870 xref: UniGene:Hs.427236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059043 ! MDFIC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018596 name: MECP2_human def: "Methyl-CpG-binding protein 2 gene" [UniProtKB:P51608] xref: EMBL:AF030876 xref: EMBL:AF158180 xref: EMBL:AJ132917 xref: EMBL:AY541280 xref: EMBL:BC011612 xref: EMBL:BX538060 xref: EMBL:L37298 xref: EMBL:X89430 xref: EMBL:X94628 xref: EMBL:X99686 xref: EMBL:Y12643 xref: HGNC:HGNC:6990 xref: UniGene:Hs.200716 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055470 ! MECP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018597 name: MED19_human def: "Mediator of RNA polymerase II transcription subunit 19 gene" [UniProtKB:A0JLT2] synonym: "LCMR1" EXACT [UniProtKB:A0JLT2] xref: EMBL:AY148462 xref: EMBL:BC009723 xref: EMBL:BC037223 xref: EMBL:CH471076 xref: HGNC:HGNC:29600 xref: UniGene:Hs.43619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053702 ! MED19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018598 name: MED25_human def: "Mediator of RNA polymerase II transcription subunit 25 gene" [UniProtKB:Q71SY5] synonym: "ACID1" EXACT [UniProtKB:Q71SY5] synonym: "ARC92" EXACT [UniProtKB:Q71SY5] synonym: "PTOV2" EXACT [UniProtKB:Q71SY5] synonym: "TCBAP0758" EXACT [UniProtKB:Q71SY5] xref: EMBL:AC006942 xref: EMBL:AF261072 xref: EMBL:AF283769 xref: EMBL:AJ617479 xref: EMBL:AL136746 xref: EMBL:AY533507 xref: EMBL:BC024312 xref: EMBL:BC065297 xref: EMBL:CH471177 xref: HGNC:HGNC:28845 xref: UniGene:Hs.656639 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057098 ! MED25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018599 name: MEF2A_human def: "Myocyte-specific enhancer factor 2A gene" [UniProtKB:Q02078] synonym: "MEF2" EXACT [UniProtKB:Q02078] xref: EMBL:BC013437 xref: EMBL:U44889 xref: EMBL:U49012 xref: EMBL:U49013 xref: EMBL:U49015 xref: EMBL:U49016 xref: EMBL:U49017 xref: EMBL:U49018 xref: EMBL:U49019 xref: EMBL:U49020 xref: EMBL:X63381 xref: EMBL:X68503 xref: EMBL:X68505 xref: EMBL:Y16312 xref: HGNC:HGNC:6993 xref: UniGene:Hs.268675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055702 ! MEF2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018600 name: MEF2B_human def: "Myocyte-specific enhancer factor 2B gene" [UniProtKB:Q02080] synonym: "XMEF2" EXACT [UniProtKB:Q02080] xref: EMBL:AC002126 xref: EMBL:BC126245 xref: EMBL:X63380 xref: EMBL:X68502 xref: HGNC:HGNC:6995 xref: UniGene:Hs.153629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055703 ! MEF2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018601 name: MEF2C_human def: "Myocyte-specific enhancer factor 2C gene" [UniProtKB:Q06413] xref: EMBL:L08895 xref: EMBL:S57212 xref: HGNC:HGNC:6996 xref: UniGene:Hs.699175 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055768 ! MEF2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018602 name: MEF2D_human def: "Myocyte-specific enhancer factor 2D gene" [UniProtKB:Q14814] xref: EMBL:AL139412 xref: EMBL:BC040949 xref: EMBL:BC054520 xref: EMBL:L16794 xref: EMBL:L16795 xref: HGNC:HGNC:6997 xref: UniGene:Hs.314327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056017 ! MEF2D_HUMAN relationship: codes_for CCO:B0056602 ! Q5T9U4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018603 name: MEOX1_human def: "Homeobox protein MOX-1 gene" [UniProtKB:P50221] synonym: "MOX1" EXACT [UniProtKB:P50221] xref: EMBL:AC068675 xref: EMBL:BC069474 xref: EMBL:BC069506 xref: EMBL:U10492 xref: HGNC:HGNC:7013 xref: UniGene:Hs.438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054078 ! A8MWF9_HUMAN relationship: codes_for CCO:B0055445 ! MEOX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018604 name: MERTK_human def: "Proto-oncogene tyrosine-protein kinase MER precursor gene" [UniProtKB:Q12866] synonym: "MER" EXACT [UniProtKB:Q12866] xref: EMBL:AC093675 xref: EMBL:AC104651 xref: EMBL:AF260514 xref: EMBL:AF260515 xref: EMBL:AF260516 xref: EMBL:AF260517 xref: EMBL:AF260518 xref: EMBL:AF260519 xref: EMBL:AF260520 xref: EMBL:AF260521 xref: EMBL:AF260522 xref: EMBL:AF260523 xref: EMBL:AF260524 xref: EMBL:AF260525 xref: EMBL:AF260526 xref: EMBL:AF260527 xref: EMBL:AF260528 xref: EMBL:AF260529 xref: EMBL:U08023 xref: HGNC:HGNC:7027 xref: UniGene:Hs.306178 xref: UniGene:Hs.677398 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018657 ! MERTK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018605 name: MESP1_human def: "Mesoderm posterior protein 1 gene" [UniProtKB:Q9BRJ9] xref: EMBL:AL357533 xref: EMBL:AL357534 xref: EMBL:BC006219 xref: HGNC:HGNC:29658 xref: UniGene:Hs.447531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058493 ! MESP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018606 name: MESP2_human def: "Mesoderm posterior protein 2 gene" [UniProtKB:Q0VG99] synonym: "SCDO2" EXACT [UniProtKB:Q0VG99] xref: EMBL:BC111413 xref: EMBL:BK000142 xref: HGNC:HGNC:29659 xref: UniGene:Hs.37311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055827 ! MESP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018607 name: METRN_human def: "Meteorin precursor gene" [UniProtKB:Q9UJH8] synonym: "C16orf23" EXACT [UniProtKB:Q9UJH8] synonym: "RJD6" EXACT [UniProtKB:Q9UJH8] xref: EMBL:AE006464 xref: EMBL:BC000662 xref: EMBL:Z97653 xref: HGNC:HGNC:14151 xref: UniGene:Hs.533772 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059171 ! METRN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018608 name: MCF2L2_human def: "Probable guanine nucleotide exchange factor MCF2L2 gene" [UniProtKB:Q86YR7] synonym: "DRG" EXACT [UniProtKB:Q86YR7] synonym: "KIAA0861" EXACT [UniProtKB:Q86YR7] xref: EMBL:AB020668 xref: EMBL:AC069417 xref: EMBL:AC092960 xref: EMBL:AC104641 xref: EMBL:AC112647 xref: EMBL:AK124500 xref: EMBL:AY172737 xref: EMBL:BC029074 xref: EMBL:BC064632 xref: HGNC:HGNC:30319 xref: UniGene:Hs.584868 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057310 ! MF2L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018609 name: MFAP4_human def: "Microfibril-associated glycoprotein 4 precursor gene" [UniProtKB:P55083] xref: EMBL:AC124066 xref: EMBL:BC062415 xref: EMBL:CH471212 xref: EMBL:L38486 xref: HGNC:HGNC:7035 xref: UniGene:Hs.296049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020123 ! MFAP4_HUMAN relationship: codes_for CCO:B0054060 ! A8MVM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018610 name: MFHAS1_human def: "Malignant fibrous histiocytoma-amplified sequence 1 gene" [UniProtKB:Q9Y4C4] synonym: "MASL1" EXACT [UniProtKB:Q9Y4C4] xref: EMBL:AB016816 xref: EMBL:BC014226 xref: HGNC:HGNC:16982 xref: UniGene:Hs.379414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059358 ! MFHA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018611 name: MGMT_human def: "Methylated-DNA--protein-cysteine methyltransferase gene" [UniProtKB:P16455] xref: EMBL:AL157832 xref: EMBL:AL355531 xref: EMBL:BC000824 xref: EMBL:BT006714 xref: EMBL:CH471066 xref: EMBL:M29971 xref: EMBL:M31767 xref: EMBL:M60761 xref: EMBL:X54228 xref: HGNC:HGNC:7059 xref: UniGene:Hs.501522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055052 ! MGMT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018612 name: MGST2_human def: "Microsomal glutathione S-transferase 2 gene" [UniProtKB:Q99735] synonym: "GST2" EXACT [UniProtKB:Q99735] xref: EMBL:AY341028 xref: EMBL:BC025416 xref: EMBL:CR407640 xref: EMBL:U77604 xref: HGNC:HGNC:7063 xref: UniGene:Hs.81874 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058450 ! MGST2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018613 name: MGST3_human def: "Microsomal glutathione S-transferase 3 gene" [UniProtKB:O14880] xref: EMBL:AF026977 xref: EMBL:AL451074 xref: EMBL:AY388493 xref: EMBL:BC000505 xref: EMBL:BC003034 xref: EMBL:BC005964 xref: EMBL:CR450359 xref: HGNC:HGNC:7064 xref: UniGene:Hs.191734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054386 ! MGST3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018614 name: MIF4GD_human def: "MIF4G domain-containing protein gene" [UniProtKB:A9UHW6] synonym: "SLIP1" EXACT [UniProtKB:A9UHW6] xref: EMBL:BC033759 xref: EMBL:CH471099 xref: EMBL:EU287989 xref: HGNC:HGNC:24030 xref: UniGene:Hs.325631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054154 ! MI4GD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018615 name: MIA3_human def: "Melanoma inhibitory activity protein 3 precursor gene" [UniProtKB:Q5JRA6] synonym: "KIAA0268" EXACT [UniProtKB:Q5JRA6] synonym: "UNQ6077/PRO20088" EXACT [UniProtKB:Q5JRA6] xref: EMBL:AK096526 xref: EMBL:AL592148 xref: EMBL:AY359091 xref: EMBL:BC047116 xref: EMBL:D87742 xref: EMBL:L34688 xref: HGNC:HGNC:24008 xref: UniGene:Hs.118474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056463 ! MIA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018616 name: MIA_human def: "Melanoma-derived growth regulatory protein precursor gene" [UniProtKB:Q16674] xref: EMBL:BC005910 xref: EMBL:BT007044 xref: EMBL:X75450 xref: EMBL:X84707 xref: HGNC:HGNC:7076 xref: UniGene:Hs.646364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056175 ! MIA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018617 name: MIB1_human def: "E3 ubiquitin-protein ligase MIB1 gene" [UniProtKB:Q86YT6] synonym: "DIP1" EXACT [UniProtKB:Q86YT6] synonym: "KIAA1323" EXACT [UniProtKB:Q86YT6] synonym: "ZZANK2" EXACT [UniProtKB:Q86YT6] xref: EMBL:AB037744 xref: EMBL:AK075157 xref: EMBL:AL713705 xref: EMBL:AY147849 xref: EMBL:AY149908 xref: EMBL:BC022403 xref: EMBL:BC110581 xref: EMBL:BC110582 xref: EMBL:CR749635 xref: HGNC:HGNC:21086 xref: UniGene:Hs.140903 xref: UniGene:Hs.658808 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057312 ! MIB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018618 name: MIB2_human def: "E3 ubiquitin-protein ligase MIB2 gene" [UniProtKB:Q96AX9] synonym: "SKD" EXACT [UniProtKB:Q96AX9] synonym: "ZZANK1" EXACT [UniProtKB:Q96AX9] xref: EMBL:AB064367 xref: EMBL:AB074480 xref: EMBL:AB076691 xref: EMBL:AB076692 xref: EMBL:AB076693 xref: EMBL:AB097000 xref: EMBL:AK091610 xref: EMBL:AK095914 xref: EMBL:AK096295 xref: EMBL:AK097106 xref: EMBL:AK098785 xref: EMBL:AK122751 xref: EMBL:AK122863 xref: EMBL:AL691432 xref: EMBL:AL834527 xref: EMBL:BC016490 xref: EMBL:BC037542 xref: HGNC:HGNC:30577 xref: UniGene:Hs.135805 xref: UniGene:Hs.593430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058158 ! MIB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018619 name: MICAL1_human def: "NEDD9-interacting protein with calponin homology and LIM domains gene" [UniProtKB:Q8TDZ2] synonym: "MICAL" EXACT [UniProtKB:Q8TDZ2] synonym: "NICAL" EXACT [UniProtKB:Q8TDZ2] xref: EMBL:AB048948 xref: EMBL:AK021999 xref: EMBL:AK024500 xref: EMBL:AK025392 xref: EMBL:AL109947 xref: EMBL:AL122098 xref: EMBL:BC009972 xref: EMBL:BC042144 xref: EMBL:BC052983 xref: HGNC:HGNC:20619 xref: UniGene:Hs.33476 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057947 ! MICA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018620 name: MIER1_human def: "Mesoderm induction early response protein 1 gene" [UniProtKB:Q8N108] synonym: "KIAA1610" EXACT [UniProtKB:Q8N108] xref: EMBL:AB046830 xref: EMBL:AF515446 xref: EMBL:AF515447 xref: EMBL:AF515448 xref: EMBL:AK074990 xref: EMBL:AL139216 xref: EMBL:AL500525 xref: EMBL:AL831987 xref: EMBL:AY124186 xref: EMBL:AY124187 xref: EMBL:AY124188 xref: EMBL:AY124189 xref: EMBL:AY124190 xref: EMBL:AY124191 xref: EMBL:AY124192 xref: EMBL:AY124193 xref: EMBL:AY124194 xref: EMBL:BC017423 xref: EMBL:CR627441 xref: HGNC:HGNC:29657 xref: UniGene:Hs.652983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020321 ! MIER1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018621 name: MIER2_human def: "Mesoderm induction early response protein 2 gene" [UniProtKB:Q8N344] synonym: "KIAA1193" EXACT [UniProtKB:Q8N344] xref: EMBL:AB033019 xref: EMBL:BC028203 xref: HGNC:HGNC:29210 xref: UniGene:Hs.101891 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057452 ! MIER2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018622 name: MIER3_human def: "Mesoderm induction early response protein 3 gene" [UniProtKB:Q7Z3K6] xref: EMBL:AK093273 xref: EMBL:BC041348 xref: EMBL:BX537798 xref: EMBL:BX640907 xref: EMBL:BX648294 xref: EMBL:CR749246 xref: EMBL:CR749805 xref: HGNC:HGNC:26678 xref: UniGene:Hs.657594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057152 ! MIER3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018623 name: MIF_human def: "Macrophage migration inhibitory factor gene" [UniProtKB:P14174] synonym: "GLIF" EXACT [UniProtKB:P14174] synonym: "MMIF" EXACT [UniProtKB:P14174] xref: EMBL:AF469046 xref: EMBL:BC000447 xref: EMBL:BC007676 xref: EMBL:BC008914 xref: EMBL:BC013976 xref: EMBL:BC022414 xref: EMBL:BC053376 xref: EMBL:BT007148 xref: EMBL:CR407644 xref: EMBL:CR456520 xref: EMBL:DQ307455 xref: EMBL:L10612 xref: EMBL:L19686 xref: EMBL:M25639 xref: EMBL:M95775 xref: EMBL:Z23063 xref: HGNC:HGNC:7097 xref: UniGene:Hs.407995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055021 ! MIF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018624 name: RHOT1_human def: "Mitochondrial Rho GTPase 1 gene" [UniProtKB:Q8IXI2] synonym: "ARHT1" EXACT [UniProtKB:Q8IXI2] xref: EMBL:AC116407 xref: EMBL:AJ496730 xref: EMBL:AJ517412 xref: EMBL:AK001902 xref: EMBL:AK022695 xref: EMBL:AL136929 xref: EMBL:AY094972 xref: EMBL:BC015698 xref: EMBL:BC041114 xref: EMBL:BC051818 xref: EMBL:BC060781 xref: EMBL:BC068463 xref: EMBL:BC125104 xref: EMBL:BC125105 xref: HGNC:HGNC:21168 xref: UniGene:Hs.655325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057378 ! MIRO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018625 name: RHOT2_human def: "Mitochondrial Rho GTPase 2 gene" [UniProtKB:Q8IXI1] synonym: "ARHT2" EXACT [UniProtKB:Q8IXI1] synonym: "C16orf39" EXACT [UniProtKB:Q8IXI1] xref: EMBL:AE006464 xref: EMBL:AJ517413 xref: EMBL:AK024450 xref: EMBL:AK090426 xref: EMBL:AY207375 xref: EMBL:BC004327 xref: EMBL:BC014942 xref: HGNC:HGNC:21169 xref: UniGene:Hs.513242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057377 ! MIRO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018626 name: MIST_human def: "Mast cell immunoreceptor signal transducer gene" [UniProtKB:Q7Z7G1] synonym: "CLNK" EXACT [UniProtKB:Q7Z7G1] xref: EMBL:AB032369 xref: EMBL:AB110420 xref: EMBL:AC005599 xref: EMBL:BC029887 xref: UniGene:Hs.678910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057213 ! MIST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018627 name: MITF_human def: "Microphthalmia-associated transcription factor gene" [UniProtKB:O75030] xref: EMBL:AB006909 xref: EMBL:AB006989 xref: EMBL:AB009608 xref: EMBL:AB032357 xref: EMBL:AB032358 xref: EMBL:AB032359 xref: EMBL:AF034755 xref: EMBL:AL110195 xref: EMBL:BC026961 xref: EMBL:BC065243 xref: EMBL:Z29678 xref: HGNC:HGNC:7105 xref: UniGene:Hs.166017 xref: UniGene:Hs.618266 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054595 ! MITF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018628 name: MIXL1_human def: "Homeobox protein MIXL1 gene" [UniProtKB:Q9H2W2] synonym: "MIXL" EXACT [UniProtKB:Q9H2W2] xref: EMBL:AF211891 xref: EMBL:AF218357 xref: EMBL:AL592045 xref: EMBL:BC111974 xref: EMBL:BC113441 xref: EMBL:CH471098 xref: HGNC:HGNC:13363 xref: UniGene:Hs.282079 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058690 ! MIXL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018629 name: MIZF_human def: "MBD2-interacting zinc finger protein gene" [UniProtKB:Q9BQA5] synonym: "ZNF743" EXACT [UniProtKB:Q9BQA5] xref: EMBL:AL080201 xref: EMBL:BC001073 xref: EMBL:BC001945 xref: EMBL:BC012856 xref: EMBL:BC017234 xref: HGNC:HGNC:17850 xref: UniGene:Hs.504091 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058478 ! MIZF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018630 name: MAP2K1IP1_human def: "Mitogen-activated protein kinase kinase 1-interacting protein 1 gene" [UniProtKB:Q9UHA4] synonym: "PRO2783" EXACT [UniProtKB:Q9UHA4] xref: EMBL:AF130115 xref: EMBL:AF201947 xref: EMBL:BC026245 xref: HGNC:HGNC:15606 xref: UniGene:Hs.696082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059131 ! MK1I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018631 name: MKL1_human def: "MKL/myocardin-like protein 1 gene" [UniProtKB:Q969V6] synonym: "KIAA1438" EXACT [UniProtKB:Q969V6] synonym: "MAL" EXACT [UniProtKB:Q969V6] xref: EMBL:AB037859 xref: EMBL:AF364035 xref: EMBL:AF368061 xref: EMBL:AJ297257 xref: EMBL:AJ297258 xref: EMBL:AJ303089 xref: EMBL:AJ303090 xref: EMBL:AL022238 xref: EMBL:AL713710 xref: EMBL:CR456522 xref: HGNC:HGNC:14334 xref: UniGene:Hs.654688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058143 ! MKL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018632 name: MKL2_human def: "MKL/myocardin-like protein 2 gene" [UniProtKB:Q9ULH7] synonym: "KIAA1243" EXACT [UniProtKB:Q9ULH7] synonym: "MRTFB" EXACT [UniProtKB:Q9ULH7] xref: EMBL:AB033069 xref: EMBL:AC130650 xref: EMBL:AK093577 xref: EMBL:AY374297 xref: EMBL:BC047761 xref: EMBL:CR749797 xref: HGNC:HGNC:29819 xref: UniGene:Hs.592047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059226 ! MKL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018633 name: MKNK1_human def: "MAP kinase-interacting serine/threonine-protein kinase 1 gene" [UniProtKB:Q9BUB5] synonym: "MNK1" EXACT [UniProtKB:Q9BUB5] xref: EMBL:AB000409 xref: EMBL:AL136373 xref: EMBL:AY355461 xref: EMBL:BC002755 xref: HGNC:HGNC:7110 xref: UniGene:Hs.371594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058519 ! MKNK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018634 name: MKNK2_human def: "MAP kinase-interacting serine/threonine-protein kinase 2 gene" [UniProtKB:Q9HBH9] synonym: "GPRK7" EXACT [UniProtKB:Q9HBH9] synonym: "MNK2" EXACT [UniProtKB:Q9HBH9] xref: EMBL:AF125532 xref: EMBL:AF237775 xref: EMBL:AF237776 xref: EMBL:BC073140 xref: HGNC:HGNC:7111 xref: UniGene:Hs.515032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058786 ! MKNK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018635 name: MKX_human def: "Homeobox protein Mohawk gene" [UniProtKB:Q8IYA7] synonym: "C10orf48" EXACT [UniProtKB:Q8IYA7] synonym: "IRXL1" EXACT [UniProtKB:Q8IYA7] xref: EMBL:BC036207 xref: HGNC:HGNC:23729 xref: UniGene:Hs.128193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031066 ! MKX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018636 name: MYL2_human def: "Myosin regulatory light chain 2, ventricular/cardiac muscle isoform gene" [UniProtKB:P10916] xref: EMBL:AF020768 xref: EMBL:BC015821 xref: EMBL:BC031006 xref: EMBL:BC031008 xref: EMBL:M22815 xref: EMBL:S69022 xref: EMBL:X14332 xref: HGNC:HGNC:7583 xref: UniGene:Hs.75535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054982 ! MLRV_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018637 name: MLXIP_human def: "MLX-interacting protein gene" [UniProtKB:Q9HAP2] synonym: "KIAA0867" EXACT [UniProtKB:Q9HAP2] synonym: "MIR" EXACT [UniProtKB:Q9HAP2] xref: EMBL:AB020674 xref: EMBL:AF245480 xref: EMBL:AF245481 xref: EMBL:AF312918 xref: EMBL:BC017656 xref: EMBL:BC028309 xref: EMBL:BC039704 xref: HGNC:HGNC:17055 xref: UniGene:Hs.437153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058765 ! MLXIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018638 name: MLX_human def: "Max-like protein X gene" [UniProtKB:Q9UH92] synonym: "TCFL4" EXACT [UniProtKB:Q9UH92] xref: EMBL:AF203978 xref: EMBL:AF213666 xref: EMBL:AF213667 xref: EMBL:AF213668 xref: EMBL:AK000150 xref: EMBL:BC010689 xref: EMBL:BT009812 xref: HGNC:HGNC:11645 xref: UniGene:Hs.383019 xref: UniGene:Hs.702050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059130 ! MLX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018639 name: MMP14_human def: "Matrix metalloproteinase-14 precursor gene" [UniProtKB:P50281] xref: EMBL:AY795074 xref: EMBL:BC064803 xref: EMBL:D26512 xref: EMBL:U41078 xref: EMBL:X83535 xref: EMBL:X90925 xref: EMBL:Z48481 xref: HGNC:HGNC:7160 xref: UniGene:Hs.2399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055446 ! MMP14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018640 name: MMP9_human def: "Matrix metalloproteinase-9 precursor gene" [UniProtKB:P14780] synonym: "CLG4B" EXACT [UniProtKB:P14780] xref: EMBL:AF538844 xref: EMBL:AL162458 xref: EMBL:BC006093 xref: EMBL:D10051 xref: EMBL:DQ194553 xref: EMBL:J05070 xref: EMBL:M68343 xref: EMBL:M68344 xref: EMBL:M68345 xref: EMBL:M68346 xref: EMBL:M68347 xref: EMBL:M68348 xref: EMBL:M68349 xref: EMBL:M68350 xref: EMBL:M68351 xref: EMBL:M68352 xref: EMBL:M68353 xref: EMBL:M68354 xref: EMBL:M68355 xref: HGNC:HGNC:7176 xref: UniGene:Hs.297413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055029 ! MMP9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018641 name: MMS19_human def: "MMS19 nucleotide excision repair protein homolog gene" [UniProtKB:Q96T76] synonym: "MMS19L" EXACT [UniProtKB:Q96T76] xref: EMBL:AF319947 xref: EMBL:AF357881 xref: EMBL:AJ306408 xref: EMBL:AK027710 xref: EMBL:AK056581 xref: EMBL:AL355490 xref: EMBL:AL359388 xref: EMBL:AY974244 xref: EMBL:BC002692 xref: EMBL:BC006575 xref: EMBL:BC007298 xref: EMBL:BC009396 xref: EMBL:BC080532 xref: EMBL:BC117129 xref: HGNC:HGNC:13824 xref: UniGene:Hs.500721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058403 ! MMS19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018642 name: MNDA_human def: "Myeloid cell nuclear differentiation antigen gene" [UniProtKB:P41218] xref: EMBL:BC032319 xref: EMBL:M81750 xref: HGNC:HGNC:7183 xref: UniGene:Hs.153837 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015979 ! MNDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018643 name: RAGE_human def: "MAPK/MAK/MRK overlapping kinase gene" [UniProtKB:Q9UQ07] synonym: "MOK" EXACT [UniProtKB:Q9UQ07] synonym: "RAGE1" EXACT [UniProtKB:Q9UQ07] xref: EMBL:AB022694 xref: EMBL:BC053536 xref: EMBL:U46191 xref: EMBL:U46192 xref: EMBL:U46193 xref: EMBL:U46194 xref: HGNC:HGNC:9833 xref: UniGene:Hs.104119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059274 ! MOK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018644 name: MORC3_human def: "MORC family CW-type zinc finger protein 3 gene" [UniProtKB:Q14149] synonym: "KIAA0136" EXACT [UniProtKB:Q14149] synonym: "ZCWCC3" EXACT [UniProtKB:Q14149] xref: EMBL:AP000692 xref: EMBL:AP000693 xref: EMBL:D50926 xref: HGNC:HGNC:23572 xref: UniGene:Hs.421150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055963 ! MORC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018645 name: MLN_human def: "Promotilin precursor gene" [UniProtKB:P12872] xref: EMBL:BC069675 xref: EMBL:M30278 xref: EMBL:M30279 xref: EMBL:M30280 xref: EMBL:M30281 xref: EMBL:X15393 xref: EMBL:X15394 xref: EMBL:X15395 xref: EMBL:X15396 xref: EMBL:Y00695 xref: HGNC:HGNC:7141 xref: UniGene:Hs.2813 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055007 ! MOTI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018646 name: MOXD1_human def: "DBH-like monooxygenase protein 1 precursor gene" [UniProtKB:Q6UVY6] synonym: "MOX" EXACT [UniProtKB:Q6UVY6] synonym: "UNQ2493/PRO5780" EXACT [UniProtKB:Q6UVY6] xref: EMBL:AK074879 xref: EMBL:AL023578 xref: EMBL:AL080058 xref: EMBL:AL357034 xref: EMBL:AY007239 xref: EMBL:AY359094 xref: EMBL:BC018756 xref: EMBL:CH471051 xref: HGNC:HGNC:21063 xref: UniGene:Hs.6909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056951 ! MOXD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018647 name: MOXD2_human def: "Putative DBH-like monooxygenase protein 2 precursor gene" [UniProtKB:A6NHM9] xref: EMBL:DY655575 xref: EMBL:U66059 xref: HGNC:HGNC:33605 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053850 ! MOXD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018648 name: MPP2_human def: "MAGUK p55 subfamily member 2 gene" [UniProtKB:Q14168] synonym: "DLG2" EXACT [UniProtKB:Q14168] xref: EMBL:AK223560 xref: EMBL:AL136554 xref: EMBL:BC030287 xref: EMBL:CR936598 xref: EMBL:X82895 xref: HGNC:HGNC:7220 xref: UniGene:Hs.514208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055968 ! MPP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018649 name: IGF2R_human def: "Cation-independent mannose-6-phosphate receptor precursor gene" [UniProtKB:P11717] synonym: "MPRI" EXACT [UniProtKB:P11717] xref: EMBL:AF069333 xref: EMBL:AF109244 xref: EMBL:AF109245 xref: EMBL:AF109246 xref: EMBL:AF109247 xref: EMBL:AF109248 xref: EMBL:AF109249 xref: EMBL:AF109250 xref: EMBL:AF109251 xref: EMBL:AF109252 xref: EMBL:AF109253 xref: EMBL:AF109254 xref: EMBL:AF109255 xref: EMBL:AF109256 xref: EMBL:AF109257 xref: EMBL:AF109258 xref: EMBL:AF109259 xref: EMBL:AF109260 xref: EMBL:AF109261 xref: EMBL:AF109262 xref: EMBL:AF109263 xref: EMBL:AF109264 xref: EMBL:AF109265 xref: EMBL:AF109266 xref: EMBL:AF109267 xref: EMBL:AF109268 xref: EMBL:AF109269 xref: EMBL:AF109270 xref: EMBL:AF109271 xref: EMBL:AF109272 xref: EMBL:AF109273 xref: EMBL:AF109274 xref: EMBL:AF109275 xref: EMBL:AF109276 xref: EMBL:AF109277 xref: EMBL:AF109278 xref: EMBL:AF109279 xref: EMBL:AF109280 xref: EMBL:AF109281 xref: EMBL:AF109282 xref: EMBL:AF109283 xref: EMBL:AF109284 xref: EMBL:AF109285 xref: EMBL:AF109286 xref: EMBL:AF109287 xref: EMBL:AF109288 xref: EMBL:AF109289 xref: EMBL:AF109290 xref: EMBL:AF109291 xref: EMBL:AL035691 xref: EMBL:AL353625 xref: EMBL:AY293855 xref: EMBL:J03528 xref: EMBL:Y00285 xref: HGNC:HGNC:5467 xref: UniGene:Hs.487062 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054994 ! MPRI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018650 name: MPZL1_human def: "Myelin protein zero-like protein 1 precursor gene" [UniProtKB:O95297] synonym: "PZR" EXACT [UniProtKB:O95297] synonym: "UNQ849/PRO1787" EXACT [UniProtKB:O95297] xref: EMBL:AF087020 xref: EMBL:AF092424 xref: EMBL:AF092425 xref: EMBL:AF095726 xref: EMBL:AF095727 xref: EMBL:AF239756 xref: EMBL:AF478447 xref: EMBL:AF478448 xref: EMBL:AL356532 xref: EMBL:AY359019 xref: EMBL:BC007881 xref: EMBL:CR542160 xref: EMBL:Z99943 xref: HGNC:HGNC:7226 xref: UniGene:Hs.493919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054748 ! MPZL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018651 name: CDC42BPA_human def: "Serine/threonine-protein kinase MRCK alpha gene" [UniProtKB:Q5VT25] synonym: "KIAA0451" EXACT [UniProtKB:Q5VT25] xref: EMBL:AB007920 xref: EMBL:AB208968 xref: EMBL:AJ518975 xref: EMBL:AJ518976 xref: EMBL:AL353689 xref: EMBL:AL451047 xref: EMBL:AL627308 xref: EMBL:CR933723 xref: EMBL:U59305 xref: HGNC:HGNC:1737 xref: UniGene:Hs.35433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056593 ! Q5T7A0_HUMAN relationship: codes_for CCO:B0056646 ! MRCKA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018652 name: CDC42BPB_human def: "Serine/threonine-protein kinase MRCK beta gene" [UniProtKB:Q9Y5S2] synonym: "KIAA1124" EXACT [UniProtKB:Q9Y5S2] xref: EMBL:AB032950 xref: EMBL:AF128625 xref: EMBL:BC047871 xref: EMBL:DQ355971 xref: HGNC:HGNC:1738 xref: UniGene:Hs.654634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059385 ! MRCKB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018653 name: CDC42BPG_human def: "Serine/threonine-protein kinase MRCK gamma gene" [UniProtKB:Q6DT37] synonym: "DMPK2" EXACT [UniProtKB:Q6DT37] xref: EMBL:AY648038 xref: EMBL:Y12337 xref: HGNC:HGNC:29829 xref: UniGene:Hs.293590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056729 ! MRCKG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018654 name: MRGPRD_human def: "Mas-related G-protein coupled receptor member D gene" [UniProtKB:Q8TDS7] synonym: "MRGD" EXACT [UniProtKB:Q8TDS7] xref: EMBL:AB065786 xref: EMBL:AB083627 xref: EMBL:AB154410 xref: EMBL:AY427820 xref: HGNC:HGNC:29626 xref: UniGene:Hs.527802 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057934 ! MRGRD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018655 name: MRGPRG_human def: "Mas-related G-protein coupled receptor member G gene" [UniProtKB:Q86SM5] synonym: "GPR169" EXACT [UniProtKB:Q86SM5] synonym: "MRGG" EXACT [UniProtKB:Q86SM5] xref: EMBL:AC109309 xref: EMBL:AY255583 xref: HGNC:HGNC:24829 xref: UniGene:Hs.647287 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057229 ! MRGRG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018656 name: MRGPRX1_human def: "Mas-related G-protein coupled receptor member X1 gene" [UniProtKB:Q96LB2] synonym: "MRGX1" EXACT [UniProtKB:Q96LB2] synonym: "SNSR3" EXACT [UniProtKB:Q96LB2] synonym: "SNSR4" EXACT [UniProtKB:Q96LB2] xref: EMBL:AB065846 xref: EMBL:AB083628 xref: EMBL:AF474989 xref: EMBL:AF474990 xref: EMBL:AY042213 xref: EMBL:BC096835 xref: HGNC:HGNC:17962 xref: UniGene:Hs.350565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058271 ! MRGX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018657 name: MRGPRX2_human def: "Mas-related G-protein coupled receptor member X2 gene" [UniProtKB:Q96LB1] synonym: "MRGX2" EXACT [UniProtKB:Q96LB1] xref: EMBL:AB065811 xref: EMBL:AB083626 xref: EMBL:AY042214 xref: EMBL:AY651130 xref: EMBL:AY651131 xref: EMBL:AY651132 xref: EMBL:AY651133 xref: EMBL:AY651134 xref: EMBL:AY651135 xref: EMBL:AY651136 xref: EMBL:AY651137 xref: EMBL:AY651138 xref: EMBL:AY651139 xref: EMBL:AY651140 xref: EMBL:AY651141 xref: EMBL:AY651142 xref: EMBL:AY651143 xref: EMBL:AY651144 xref: EMBL:AY651145 xref: EMBL:AY651146 xref: EMBL:AY651147 xref: EMBL:AY651148 xref: EMBL:AY651149 xref: EMBL:AY651150 xref: EMBL:AY651151 xref: EMBL:AY651152 xref: EMBL:AY651153 xref: EMBL:AY651154 xref: EMBL:AY651155 xref: EMBL:AY651156 xref: EMBL:AY651157 xref: EMBL:AY651158 xref: EMBL:AY651159 xref: EMBL:AY651160 xref: EMBL:AY651161 xref: EMBL:AY845175 xref: EMBL:AY845176 xref: EMBL:BC063450 xref: HGNC:HGNC:17983 xref: UniGene:Hs.350566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058270 ! MRGX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018658 name: MRGPRX3_human def: "Mas-related G-protein coupled receptor member X3 gene" [UniProtKB:Q96LB0] synonym: "MRGX3" EXACT [UniProtKB:Q96LB0] synonym: "SNSR1" EXACT [UniProtKB:Q96LB0] synonym: "SNSR2" EXACT [UniProtKB:Q96LB0] xref: EMBL:AF474987 xref: EMBL:AF474988 xref: EMBL:AY042215 xref: EMBL:BC067292 xref: HGNC:HGNC:17980 xref: UniGene:Hs.380177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058269 ! MRGX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018659 name: MRGPRX4_human def: "Mas-related G-protein coupled receptor member X4 gene" [UniProtKB:Q96LA9] synonym: "MRGX4" EXACT [UniProtKB:Q96LA9] synonym: "SNSR5" EXACT [UniProtKB:Q96LA9] synonym: "SNSR6" EXACT [UniProtKB:Q96LA9] xref: EMBL:AF474991 xref: EMBL:AF474992 xref: EMBL:AY042216 xref: EMBL:BC095509 xref: EMBL:BC107099 xref: EMBL:BC107100 xref: HGNC:HGNC:17617 xref: UniGene:Hs.632138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058268 ! MRGX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018660 name: MRLC3_human def: "Myosin regulatory light chain MRLC3 gene" [UniProtKB:P19105] synonym: "MLCB" EXACT [UniProtKB:P19105] synonym: "RLC" EXACT [UniProtKB:P19105] xref: EMBL:BC016372 xref: EMBL:BC031972 xref: EMBL:BC032748 xref: EMBL:X54304 xref: UniGene:Hs.190086 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061987 ! MRLC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018661 name: MSL3L1_human def: "Male-specific lethal-3 protein-like 1 gene" [UniProtKB:Q8N5Y2] xref: EMBL:AF117065 xref: EMBL:AL050178 xref: EMBL:AL713667 xref: EMBL:BC031210 xref: HGNC:HGNC:7370 xref: UniGene:Hs.655288 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057482 ! MS3L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018662 name: MS4A3_human def: "Membrane-spanning 4-domains subfamily A member 3 gene" [UniProtKB:Q96HJ5] synonym: "CD20L" EXACT [UniProtKB:Q96HJ5] synonym: "HTM4" EXACT [UniProtKB:Q96HJ5] xref: EMBL:AP000790 xref: EMBL:AY095480 xref: EMBL:AY258289 xref: EMBL:BC008487 xref: EMBL:L35848 xref: HGNC:HGNC:7317 xref: UniGene:Hs.99960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054032 ! A8MTP8_HUMAN relationship: codes_for CCO:B0058222 ! MS4A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018663 name: MS4A5_human def: "Membrane-spanning 4-domains subfamily A member 5 gene" [UniProtKB:Q9H3V2] synonym: "CD20L2" EXACT [UniProtKB:Q9H3V2] synonym: "TETM4" EXACT [UniProtKB:Q9H3V2] xref: EMBL:AB013103 xref: EMBL:AF237907 xref: EMBL:AF321127 xref: EMBL:BC029884 xref: HGNC:HGNC:13374 xref: UniGene:Hs.178066 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058711 ! MS4A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018664 name: MSGN1_human def: "Mesogenin-1 gene" [UniProtKB:A6NI15] xref: EMBL:AC093731 xref: HGNC:HGNC:14907 xref: UniGene:Hs.705359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053855 ! MSGN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018665 name: RABIF_human def: "Guanine nucleotide exchange factor MSS4 gene" [UniProtKB:P47224] synonym: "MSS4" EXACT [UniProtKB:P47224] synonym: "RASGRF3" EXACT [UniProtKB:P47224] xref: EMBL:BC018488 xref: EMBL:BC037392 xref: EMBL:BT007133 xref: EMBL:S78873 xref: EMBL:U74324 xref: HGNC:HGNC:9797 xref: UniGene:Hs.90875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055383 ! MSS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018666 name: MSX1_human def: "Homeobox protein MSX-1 gene" [UniProtKB:P28360] synonym: "HOX7" EXACT [UniProtKB:P28360] xref: EMBL:AF426432 xref: EMBL:BC021285 xref: EMBL:BC067353 xref: EMBL:M76731 xref: EMBL:M76732 xref: EMBL:M97676 xref: HGNC:HGNC:7391 xref: UniGene:Hs.424414 xref: UniGene:Hs.621772 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055203 ! MSX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018667 name: MSX2_human def: "Homeobox protein MSX-2 gene" [UniProtKB:P35548] synonym: "HOX8" EXACT [UniProtKB:P35548] xref: EMBL:BC015509 xref: EMBL:D14970 xref: EMBL:D31771 xref: EMBL:D89377 xref: EMBL:L22498 xref: EMBL:L22499 xref: EMBL:S75308 xref: EMBL:S75361 xref: EMBL:X69295 xref: HGNC:HGNC:7392 xref: UniGene:Hs.89404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055294 ! MSX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018668 name: MT2A_human def: "Metallothionein-2 gene" [UniProtKB:P02795] synonym: "CES1" EXACT [UniProtKB:P02795] synonym: "MT2" EXACT [UniProtKB:P02795] xref: EMBL:BC007034 xref: EMBL:BC070289 xref: EMBL:BT007315 xref: EMBL:DQ370420 xref: EMBL:J00271 xref: EMBL:M26637 xref: EMBL:S52379 xref: EMBL:V00594 xref: EMBL:X97260 xref: HGNC:HGNC:7406 xref: UniGene:Hs.647371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054877 ! MT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018669 name: MT3_human def: "Metallothionein-3 gene" [UniProtKB:P25713] xref: EMBL:BC013081 xref: EMBL:BT007030 xref: EMBL:D13365 xref: EMBL:DQ297144 xref: EMBL:M93311 xref: EMBL:S72043 xref: EMBL:X89604 xref: HGNC:HGNC:7408 xref: UniGene:Hs.73133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055185 ! MT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018670 name: MTA1_human def: "Metastasis-associated protein MTA1 gene" [UniProtKB:Q13330] xref: EMBL:AF508978 xref: EMBL:BC009443 xref: EMBL:U35113 xref: HGNC:HGNC:7410 xref: UniGene:Hs.525629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055899 ! MTA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018671 name: MTA2_human def: "Metastasis-associated protein MTA2 gene" [UniProtKB:O94776] synonym: "MTA1L1" EXACT [UniProtKB:O94776] synonym: "PID" EXACT [UniProtKB:O94776] xref: EMBL:AB012922 xref: EMBL:AB016591 xref: EMBL:AF295807 xref: EMBL:BC023656 xref: EMBL:BC053650 xref: HGNC:HGNC:7411 xref: UniGene:Hs.173043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054698 ! MTA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018672 name: MTA3_human def: "Metastasis-associated protein MTA3 gene" [UniProtKB:Q9BTC8] synonym: "KIAA1266" EXACT [UniProtKB:Q9BTC8] xref: EMBL:AB033092 xref: EMBL:AK027304 xref: EMBL:AL161954 xref: EMBL:BC004227 xref: EMBL:BC053631 xref: HGNC:HGNC:23784 xref: UniGene:Hs.435413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058514 ! MTA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018673 name: MTCH1_human def: "Mitochondrial carrier homolog 1 gene" [UniProtKB:Q9NZJ7] synonym: "CGI-64" EXACT [UniProtKB:Q9NZJ7] synonym: "PSAP" EXACT [UniProtKB:Q9NZJ7] synonym: "UNQ1871/PRO4314" EXACT [UniProtKB:Q9NZJ7] xref: EMBL:AF176006 xref: EMBL:AF189289 xref: EMBL:AF192559 xref: EMBL:AL122034 xref: EMBL:AY358519 xref: EMBL:BC000702 xref: EMBL:BC006507 xref: EMBL:BC009962 xref: EMBL:BC040659 xref: EMBL:BC110914 xref: HGNC:HGNC:17586 xref: UniGene:Hs.485262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057354 ! Q8IW90_HUMAN relationship: codes_for CCO:B0059001 ! MTCH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018674 name: MTERFD3_human def: "mTERF domain-containing protein 3, mitochondrial precursor gene" [UniProtKB:Q49AM1] xref: EMBL:AK024124 xref: EMBL:AK222558 xref: EMBL:AL832827 xref: EMBL:AY008301 xref: EMBL:BC025984 xref: EMBL:BC036066 xref: HGNC:HGNC:30779 xref: UniGene:Hs.5009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016003 ! MTER3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018675 name: MTERF_human def: "Transcription termination factor, mitochondrial precursor gene" [UniProtKB:Q99551] xref: EMBL:AC003086 xref: EMBL:BC000965 xref: EMBL:BC108648 xref: EMBL:BC130389 xref: EMBL:BC130391 xref: EMBL:Y09615 xref: HGNC:HGNC:21463 xref: UniGene:Hs.532216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016000 ! MTERF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018676 name: MTF1_human def: "Metal regulatory transcription factor 1 gene" [UniProtKB:Q14872] xref: EMBL:AL929472 xref: EMBL:BC014454 xref: EMBL:X78710 xref: HGNC:HGNC:7428 xref: UniGene:Hs.471991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056022 ! MTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018677 name: CBFA2T3_human def: "Protein CBFA2T3 gene" [UniProtKB:O75081] synonym: "MTG16" EXACT [UniProtKB:O75081] synonym: "MTGR2" EXACT [UniProtKB:O75081] synonym: "ZMYND4" EXACT [UniProtKB:O75081] xref: EMBL:AB010419 xref: EMBL:AB010420 xref: EMBL:AB013286 xref: EMBL:AF052213 xref: EMBL:AF052214 xref: EMBL:AF052215 xref: EMBL:AF052216 xref: EMBL:AF052217 xref: EMBL:AF052220 xref: EMBL:BC047019 xref: EMBL:BC062624 xref: HGNC:HGNC:1537 xref: UniGene:Hs.513811 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054601 ! MTG16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018678 name: CBFA2T2_human def: "Protein CBFA2T2 gene" [UniProtKB:O43439] synonym: "EHT" EXACT [UniProtKB:O43439] synonym: "MTGR1" EXACT [UniProtKB:O43439] xref: EMBL:AF013970 xref: EMBL:AF039200 xref: EMBL:AF052210 xref: EMBL:AF068266 xref: EMBL:AF069747 xref: EMBL:AF076452 xref: EMBL:AF076453 xref: EMBL:AF076454 xref: EMBL:AF076455 xref: EMBL:AF076456 xref: EMBL:AF076457 xref: EMBL:AF076458 xref: EMBL:AF076459 xref: EMBL:AF076460 xref: EMBL:AF076461 xref: EMBL:AL034421 xref: EMBL:AL121906 xref: EMBL:AL162505 xref: EMBL:BC015066 xref: EMBL:BC016298 xref: EMBL:BC040344 xref: HGNC:HGNC:1536 xref: UniGene:Hs.153934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054482 ! MTG8R_HUMAN relationship: codes_for CCO:B0056623 ! Q5TGE8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018679 name: RUNX1T1_human def: "Protein CBFA2T1 gene" [UniProtKB:Q06455] synonym: "AML1T1" EXACT [UniProtKB:Q06455] synonym: "CBFA2T1" EXACT [UniProtKB:Q06455] synonym: "CDR" EXACT [UniProtKB:Q06455] synonym: "ETO" EXACT [UniProtKB:Q06455] synonym: "MTG8" EXACT [UniProtKB:Q06455] synonym: "ZMYND2" EXACT [UniProtKB:Q06455] xref: EMBL:AF018270 xref: EMBL:AF018271 xref: EMBL:AF018272 xref: EMBL:AF018273 xref: EMBL:AF018274 xref: EMBL:AF018275 xref: EMBL:AF018276 xref: EMBL:AF018277 xref: EMBL:AF018278 xref: EMBL:AF018279 xref: EMBL:AF018281 xref: EMBL:AF018282 xref: EMBL:AF018283 xref: EMBL:BC005850 xref: EMBL:BC067078 xref: EMBL:BT009871 xref: EMBL:CH471060 xref: EMBL:CR456792 xref: EMBL:D13979 xref: EMBL:D14289 xref: EMBL:D14821 xref: EMBL:D14822 xref: EMBL:D14823 xref: EMBL:D43638 xref: EMBL:S50186 xref: EMBL:S74092 xref: EMBL:S74096 xref: EMBL:S78158 xref: EMBL:S78159 xref: EMBL:X79990 xref: HGNC:HGNC:1535 xref: UniGene:Hs.368431 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055769 ! MTG8_HUMAN relationship: codes_for CCO:B0057165 ! Q7Z4J5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018680 name: MLNR_human def: "Motilin receptor gene" [UniProtKB:O43193] synonym: "GPR38" EXACT [UniProtKB:O43193] synonym: "MTLR" EXACT [UniProtKB:O43193] synonym: "MTLR1" EXACT [UniProtKB:O43193] xref: EMBL:AF034632 xref: EMBL:AL137000 xref: EMBL:AY603964 xref: HGNC:HGNC:4495 xref: UniGene:Hs.248126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054459 ! MTLR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018681 name: MTPN_human def: "Myotrophin gene" [UniProtKB:P58546] xref: EMBL:AC015987 xref: EMBL:BC028093 xref: HGNC:HGNC:15667 xref: UniGene:Hs.654894 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055571 ! MTPN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018682 name: MUC12_human def: "Mucin-12 precursor gene" [UniProtKB:Q9UKN1] synonym: "MUC11" EXACT [UniProtKB:Q9UKN1] xref: EMBL:AC105446 xref: EMBL:AF147790 xref: EMBL:AF147791 xref: HGNC:HGNC:7510 xref: UniGene:Hs.489355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059196 ! MUC12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018683 name: CD164_human def: "Putative mucin core protein 24 precursor gene" [UniProtKB:Q04900] xref: EMBL:AF263279 xref: EMBL:AF299340 xref: EMBL:AF299341 xref: EMBL:AK312357 xref: EMBL:AL359711 xref: EMBL:BC011522 xref: EMBL:CH471051 xref: EMBL:D14043 xref: HGNC:HGNC:1632 xref: UniGene:Hs.520313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055738 ! MUC24_HUMAN relationship: codes_for CCO:B0058883 ! Q9NR26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018684 name: MSC_human def: "Musculin gene" [UniProtKB:O60682] synonym: "ABF1" EXACT [UniProtKB:O60682] xref: EMBL:AF060154 xref: EMBL:AF087036 xref: EMBL:BC006313 xref: EMBL:BC067827 xref: HGNC:HGNC:7321 xref: UniGene:Hs.442619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054575 ! MUSC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018685 name: MX1_human def: "Interferon-induced GTP-binding protein Mx1 gene" [UniProtKB:P20591] xref: EMBL:AF135187 xref: EMBL:AL163285 xref: EMBL:BC032602 xref: EMBL:M30817 xref: EMBL:M33882 xref: HGNC:HGNC:7532 xref: UniGene:Hs.517307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055123 ! MX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018686 name: MXI1_human def: "MAX-interacting protein 1 gene" [UniProtKB:P50539] xref: EMBL:AK303949 xref: EMBL:AL360182 xref: EMBL:BC012907 xref: EMBL:BT007069 xref: EMBL:CH471066 xref: EMBL:CR536576 xref: EMBL:D63940 xref: EMBL:L07648 xref: EMBL:S78470 xref: EMBL:U32512 xref: EMBL:U32513 xref: EMBL:U32514 xref: EMBL:U32515 xref: HGNC:HGNC:7534 xref: UniGene:Hs.501023 xref: UniGene:Hs.602078 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015398 ! MXI1_HUMAN relationship: codes_for CCO:B0054260 ! B1ANN6_HUMAN relationship: codes_for CCO:B0054261 ! B1ANN7_HUMAN relationship: codes_for CCO:B0054262 ! B1ANN8_HUMAN relationship: codes_for CCO:B0054263 ! B1ANN9_HUMAN relationship: codes_for CCO:B0058201 ! Q96E53_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018687 name: MYO18A_human def: "Myosin-XVIIIa gene" [UniProtKB:Q92614] synonym: "KIAA0216" EXACT [UniProtKB:Q92614] synonym: "MYSPDZ" EXACT [UniProtKB:Q92614] xref: EMBL:AB177858 xref: EMBL:AB177860 xref: EMBL:BC039612 xref: EMBL:CR933614 xref: EMBL:D86970 xref: HGNC:HGNC:31104 xref: UniGene:Hs.462590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058072 ! MY18A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018688 name: MYBL1_human def: "Myb-related protein A gene" [UniProtKB:P10243] synonym: "AMYB" EXACT [UniProtKB:P10243] xref: EMBL:BC101188 xref: EMBL:CH471068 xref: EMBL:X13294 xref: EMBL:X66087 xref: HGNC:HGNC:7547 xref: UniGene:Hs.654538 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028510 ! MYBA_HUMAN relationship: codes_for CCO:B0028528 ! Q495F9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018689 name: MYCBP2_human def: "Probable E3 ubiquitin-protein ligase MYCBP2 gene" [UniProtKB:O75592] synonym: "KIAA0916" EXACT [UniProtKB:O75592] synonym: "PAM" EXACT [UniProtKB:O75592] xref: EMBL:AB020723 xref: EMBL:AC001226 xref: EMBL:AF075587 xref: EMBL:AF083244 xref: EMBL:AL159154 xref: EMBL:AL159158 xref: EMBL:AL359257 xref: EMBL:BC037971 xref: EMBL:CH471093 xref: HGNC:HGNC:23386 xref: UniGene:Hs.591221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054654 ! MYCB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018690 name: MYOCD_human def: "Myocardin gene" [UniProtKB:Q8IZQ8] synonym: "MYCD" EXACT [UniProtKB:Q8IZQ8] xref: EMBL:AC005358 xref: EMBL:AF532596 xref: EMBL:AK097821 xref: HGNC:HGNC:16067 xref: UniGene:Hs.567641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057412 ! MYCD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018691 name: MYCL1_human def: "L-myc-1 proto-oncogene protein gene" [UniProtKB:P12524] synonym: "LMYC" EXACT [UniProtKB:P12524] synonym: "MYCL" EXACT [UniProtKB:P12524] xref: EMBL:AL033527 xref: EMBL:BC011864 xref: EMBL:M19720 xref: EMBL:X07262 xref: EMBL:X07263 xref: HGNC:HGNC:7555 xref: UniGene:Hs.437922 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053715 ! A2A2C9_HUMAN relationship: codes_for CCO:B0055000 ! MYCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018692 name: MYCL2_human def: "L-myc-2 protein gene" [UniProtKB:P12525] xref: EMBL:J03069 xref: HGNC:HGNC:7556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055001 ! MYCL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018693 name: MYCN_human def: "N-myc proto-oncogene protein gene" [UniProtKB:P04198] synonym: "NMYC" EXACT [UniProtKB:P04198] xref: EMBL:BC002712 xref: EMBL:M13228 xref: EMBL:M13241 xref: EMBL:M18090 xref: EMBL:X02363 xref: EMBL:X03294 xref: EMBL:X03295 xref: EMBL:Y00664 xref: HGNC:HGNC:7559 xref: UniGene:Hs.25960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054887 ! MYCN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018694 name: DENND4A_human def: "C-myc promoter-binding protein gene" [UniProtKB:Q7Z401] synonym: "IRLB" EXACT [UniProtKB:Q7Z401] synonym: "MYCPBP" EXACT [UniProtKB:Q7Z401] xref: EMBL:AF534403 xref: EMBL:AK091368 xref: EMBL:AL832602 xref: EMBL:BC041706 xref: EMBL:X63417 xref: HGNC:HGNC:24321 xref: UniGene:Hs.654567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057157 ! MYCPP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018695 name: MYD88_human def: "Myeloid differentiation primary response protein MyD88 gene" [UniProtKB:Q99836] xref: EMBL:BC013589 xref: EMBL:U70451 xref: EMBL:U84408 xref: HGNC:HGNC:7562 xref: UniGene:Hs.82116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058458 ! MYD88_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018696 name: MYF5_human def: "Myogenic factor 5 gene" [UniProtKB:P13349] xref: EMBL:BC069373 xref: EMBL:CH471054 xref: EMBL:U27313 xref: EMBL:X14894 xref: HGNC:HGNC:7565 xref: UniGene:Hs.178023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055012 ! MYF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018697 name: MYF6_human def: "Myogenic factor 6 gene" [UniProtKB:P23409] xref: EMBL:BC017834 xref: EMBL:CR407641 xref: EMBL:CR541763 xref: EMBL:X52011 xref: HGNC:HGNC:7566 xref: UniGene:Hs.35937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055156 ! MYF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018698 name: MYNN_human def: "Myoneurin gene" [UniProtKB:Q9NPC7] synonym: "OSZF" EXACT [UniProtKB:Q9NPC7] synonym: "SBBIZ1" EXACT [UniProtKB:Q9NPC7] synonym: "ZBTB31" EXACT [UniProtKB:Q9NPC7] xref: EMBL:AB079777 xref: EMBL:AB079778 xref: EMBL:AB079779 xref: EMBL:AF076249 xref: EMBL:AF148848 xref: EMBL:AF155508 xref: EMBL:AK021646 xref: EMBL:AL133070 xref: EMBL:AY286321 xref: EMBL:AY286322 xref: EMBL:AY286323 xref: EMBL:AY286324 xref: EMBL:AY286325 xref: EMBL:AY286326 xref: EMBL:AY286327 xref: EMBL:AY286328 xref: EMBL:AY514901 xref: EMBL:AY515294 xref: EMBL:AY515691 xref: EMBL:AY515692 xref: EMBL:AY541760 xref: EMBL:AY541761 xref: EMBL:BC033620 xref: EMBL:BX648128 xref: HGNC:HGNC:14955 xref: UniGene:Hs.507025 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058847 ! MYNN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018699 name: MYO10_human def: "Myosin-X gene" [UniProtKB:Q9HD67] synonym: "KIAA0799" EXACT [UniProtKB:Q9HD67] xref: EMBL:AB018342 xref: EMBL:AF132021 xref: EMBL:AF132022 xref: EMBL:AF184153 xref: EMBL:AF234532 xref: EMBL:AF247457 xref: HGNC:HGNC:7593 xref: UniGene:Hs.481720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058826 ! MYO10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018700 name: MYOG_human def: "Myogenin gene" [UniProtKB:P15173] synonym: "MYF4" EXACT [UniProtKB:P15173] xref: EMBL:BC053899 xref: EMBL:X17651 xref: EMBL:X62155 xref: HGNC:HGNC:7612 xref: UniGene:Hs.2830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055031 ! MYOG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018701 name: MYBPC3_human def: "Myosin-binding protein C, cardiac-type gene" [UniProtKB:Q14896] xref: EMBL:AY518390 xref: EMBL:S80778 xref: EMBL:U91629 xref: EMBL:X84075 xref: EMBL:Y10129 xref: HGNC:HGNC:7551 xref: UniGene:Hs.524906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056023 ! MYPC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018702 name: PPP1R12B_human def: "Protein phosphatase 1 regulatory subunit 12B gene" [UniProtKB:O60237] synonym: "MYPT2" EXACT [UniProtKB:O60237] xref: EMBL:AB003062 xref: EMBL:AB050641 xref: EMBL:AB050642 xref: EMBL:AC099336 xref: EMBL:AF324888 xref: EMBL:AF324889 xref: EMBL:AF324890 xref: EMBL:AF324891 xref: EMBL:AF324892 xref: EMBL:AL356953 xref: EMBL:AL589762 xref: EMBL:BC034430 xref: HGNC:HGNC:7619 xref: UniGene:Hs.444403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054535 ! MYPT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018703 name: MYSM1_human def: "Protein MYSM1 gene" [UniProtKB:Q5VVJ2] synonym: "KIAA1915" EXACT [UniProtKB:Q5VVJ2] xref: EMBL:AB067502 xref: EMBL:AL035411 xref: EMBL:AL450024 xref: EMBL:BX537912 xref: HGNC:HGNC:29401 xref: UniGene:Hs.477495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056659 ! MYSM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018704 name: MYST1_human def: "Probable histone acetyltransferase MYST1 gene" [UniProtKB:Q9H7Z6] synonym: "MOF" EXACT [UniProtKB:Q9H7Z6] synonym: "PP7073" EXACT [UniProtKB:Q9H7Z6] xref: EMBL:AF217501 xref: EMBL:AF260665 xref: EMBL:AF289578 xref: EMBL:AK021872 xref: EMBL:AK024102 xref: EMBL:AL050395 xref: EMBL:BC037773 xref: HGNC:HGNC:17933 xref: UniGene:Hs.533803 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058748 ! MYST1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018705 name: MYT2_human def: "Replication initiation-like protein gene" [UniProtKB:O15150] xref: EMBL:AF006822 xref: EMBL:S76853 xref: HGNC:HGNC:7624 xref: UniGene:Hs.123048 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054410 ! MYT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018706 name: MZF1_human def: "Myeloid zinc finger 1 gene" [UniProtKB:P28698] synonym: "MZF" EXACT [UniProtKB:P28698] synonym: "ZNF42" EXACT [UniProtKB:P28698] synonym: "ZSCAN6" EXACT [UniProtKB:P28698] xref: EMBL:AC016629 xref: EMBL:AC016630 xref: EMBL:AF055077 xref: EMBL:AF055078 xref: EMBL:AF161886 xref: EMBL:BC053316 xref: EMBL:M58297 xref: HGNC:HGNC:13108 xref: UniGene:Hs.399810 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055206 ! MZF1_HUMAN relationship: codes_for CCO:B0057206 ! Q7Z729_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018707 name: NAB1_human def: "NGFI-A-binding protein 1 gene" [UniProtKB:Q13506] xref: EMBL:AC006460 xref: EMBL:AF045451 xref: EMBL:AF045452 xref: EMBL:AF052744 xref: EMBL:BC035724 xref: EMBL:U47007 xref: HGNC:HGNC:7626 xref: UniGene:Hs.570078 xref: UniGene:Hs.611466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055920 ! NAB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018708 name: NAB2_human def: "NGFI-A-binding protein 2 gene" [UniProtKB:Q15742] synonym: "MADER" EXACT [UniProtKB:Q15742] xref: EMBL:AF268380 xref: EMBL:AJ011081 xref: EMBL:BC065931 xref: EMBL:U48361 xref: EMBL:X70991 xref: HGNC:HGNC:7627 xref: UniGene:Hs.159223 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056102 ! NAB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018709 name: NLRP12_human def: "NACHT, LRR and PYD domains-containing protein 12 gene" [UniProtKB:P59046] synonym: "NALP12" EXACT [UniProtKB:P59046] synonym: "PYPAF7" EXACT [UniProtKB:P59046] synonym: "RNO" EXACT [UniProtKB:P59046] xref: EMBL:AF231021 xref: EMBL:AY095146 xref: EMBL:AY116204 xref: EMBL:AY116205 xref: EMBL:AY116206 xref: EMBL:AY116207 xref: EMBL:AY154467 xref: EMBL:BC028069 xref: HGNC:HGNC:22938 xref: UniGene:Hs.631573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055574 ! NAL12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018710 name: NLRP1_human def: "NACHT, LRR and PYD domains-containing protein 1 gene" [UniProtKB:Q9C000] synonym: "CARD7" EXACT [UniProtKB:Q9C000] synonym: "DEFCAP" EXACT [UniProtKB:Q9C000] synonym: "KIAA0926" EXACT [UniProtKB:Q9C000] synonym: "NAC" EXACT [UniProtKB:Q9C000] synonym: "NALP1" EXACT [UniProtKB:Q9C000] xref: EMBL:AB023143 xref: EMBL:AF229059 xref: EMBL:AF229060 xref: EMBL:AF229061 xref: EMBL:AF229062 xref: EMBL:AF298548 xref: EMBL:AF310105 xref: EMBL:AL117470 xref: HGNC:HGNC:14374 xref: UniGene:Hs.104305 xref: UniGene:Hs.652273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058613 ! NALP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018711 name: NLRP2_human def: "NACHT, LRR and PYD domains-containing protein 2 gene" [UniProtKB:Q9NX02] synonym: "NALP2" EXACT [UniProtKB:Q9NX02] synonym: "NBS1" EXACT [UniProtKB:Q9NX02] synonym: "PAN1" EXACT [UniProtKB:Q9NX02] synonym: "PYPAF2" EXACT [UniProtKB:Q9NX02] xref: EMBL:AB209300 xref: EMBL:AF298547 xref: EMBL:AF310106 xref: EMBL:AF464764 xref: EMBL:AK000517 xref: EMBL:AK000784 xref: EMBL:AK025952 xref: EMBL:AK223253 xref: EMBL:AK223269 xref: EMBL:BC001039 xref: EMBL:BC003592 xref: EMBL:BC039269 xref: HGNC:HGNC:22948 xref: UniGene:Hs.369279 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058945 ! NALP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018712 name: NLRP3_human def: "NACHT, LRR and PYD domains-containing protein 3 gene" [UniProtKB:Q96P20] synonym: "C1orf7" EXACT [UniProtKB:Q96P20] synonym: "CIAS1" EXACT [UniProtKB:Q96P20] synonym: "NALP3" EXACT [UniProtKB:Q96P20] synonym: "PYPAF1" EXACT [UniProtKB:Q96P20] xref: EMBL:AB208891 xref: EMBL:AC104335 xref: EMBL:AF054176 xref: EMBL:AF410477 xref: EMBL:AF418985 xref: EMBL:AF420469 xref: EMBL:AF427617 xref: EMBL:AF468522 xref: EMBL:AL606804 xref: EMBL:AY051112 xref: EMBL:AY051113 xref: EMBL:AY051114 xref: EMBL:AY051115 xref: EMBL:AY051116 xref: EMBL:AY051117 xref: EMBL:AY056059 xref: EMBL:AY056060 xref: EMBL:AY092033 xref: EMBL:AY422168 xref: EMBL:BC117211 xref: HGNC:HGNC:16400 xref: UniGene:Hs.159483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058316 ! NALP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018713 name: NAMPT_human def: "Nicotinamide phosphoribosyltransferase gene" [UniProtKB:P43490] synonym: "PBEF" EXACT [UniProtKB:P43490] synonym: "PBEF1" EXACT [UniProtKB:P43490] xref: EMBL:AC007032 xref: EMBL:BC020691 xref: EMBL:BC072439 xref: EMBL:BC106046 xref: EMBL:U02020 xref: HGNC:HGNC:30092 xref: UniGene:Hs.489615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055366 ! NAMPT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018714 name: NANOGP1_human def: "Putative homeobox protein NANOG2 gene" [UniProtKB:Q8N7R0] synonym: "NANOG2" EXACT [UniProtKB:Q8N7R0] xref: EMBL:AK097770 xref: EMBL:AY455283 xref: HGNC:HGNC:23099 xref: UniGene:Hs.661360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057506 ! NANG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018715 name: NANOS1_human def: "Nanos homolog 1 gene" [UniProtKB:Q8WY41] synonym: "NOS1" EXACT [UniProtKB:Q8WY41] xref: EMBL:AF275269 xref: EMBL:AF458985 xref: EMBL:AL157788 xref: HGNC:HGNC:23044 xref: UniGene:Hs.591918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058039 ! NANO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018716 name: NANOS2_human def: "Nanos homolog 2 gene" [UniProtKB:P60321] synonym: "NOS2" EXACT [UniProtKB:P60321] xref: EMBL:BC042883 xref: EMBL:BC117484 xref: EMBL:BC117486 xref: HGNC:HGNC:23292 xref: UniGene:Hs.434218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055596 ! NANO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018717 name: NANOS3_human def: "Nanos homolog 3 gene" [UniProtKB:P60323] synonym: "NOS3" EXACT [UniProtKB:P60323] xref: EMBL:AC020916 xref: EMBL:BM702754 xref: HGNC:HGNC:22048 xref: UniGene:Hs.127982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055597 ! NANO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018718 name: NANOG_human def: "Homeobox protein NANOG gene" [UniProtKB:Q9H9S0] xref: EMBL:AB093576 xref: EMBL:AK022643 xref: EMBL:AY230262 xref: EMBL:AY578089 xref: HGNC:HGNC:20857 xref: UniGene:Hs.661360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058756 ! NANOG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018719 name: NANOGP8_human def: "Homeobox protein NANOGP8 gene" [UniProtKB:Q6NSW7] xref: EMBL:BC069807 xref: EMBL:BC098275 xref: EMBL:BC099704 xref: HGNC:HGNC:23106 xref: UniGene:Hs.635882 xref: UniGene:Hs.661360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056853 ! NANP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018720 name: NARG1_human def: "NMDA receptor-regulated protein 1 gene" [UniProtKB:Q9BXJ9] synonym: "GA19" EXACT [UniProtKB:Q9BXJ9] synonym: "NATH" EXACT [UniProtKB:Q9BXJ9] synonym: "TBDN100" EXACT [UniProtKB:Q9BXJ9] xref: EMBL:AC097376 xref: EMBL:AF327722 xref: EMBL:AJ314788 xref: EMBL:AK023402 xref: EMBL:AY039242 xref: EMBL:AY112670 xref: EMBL:BC039818 xref: EMBL:BC093928 xref: EMBL:BC104806 xref: HGNC:HGNC:30782 xref: UniGene:Hs.555985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058556 ! NARG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018721 name: NARG1L_human def: "NMDA receptor-regulated 1-like protein gene" [UniProtKB:Q6N069] synonym: "NAT2" EXACT [UniProtKB:Q6N069] xref: EMBL:AK097224 xref: EMBL:AL354696 xref: EMBL:AL590665 xref: EMBL:AL731858 xref: EMBL:BC032318 xref: EMBL:BC064592 xref: EMBL:BX640665 xref: HGNC:HGNC:26164 xref: UniGene:Hs.512914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056848 ! NARGL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018722 name: NAT14_human def: "N-acetyltransferase 14 gene" [UniProtKB:Q8WUY8] synonym: "KLP1" EXACT [UniProtKB:Q8WUY8] xref: EMBL:AB038651 xref: EMBL:AB055059 xref: EMBL:BC019079 xref: HGNC:HGNC:28918 xref: UniGene:Hs.31854 xref: UniGene:Hs.653472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057985 ! NAT14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018723 name: DR1_human def: "Protein Dr1 gene" [UniProtKB:Q01658] xref: EMBL:AL137159 xref: EMBL:BC002809 xref: EMBL:BC035507 xref: EMBL:BC068553 xref: EMBL:BT006972 xref: EMBL:M97388 xref: HGNC:HGNC:3017 xref: UniGene:Hs.348418 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055692 ! NC2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018724 name: NCBP1_human def: "Nuclear cap-binding protein subunit 1 gene" [UniProtKB:Q09161] synonym: "CBP80" EXACT [UniProtKB:Q09161] synonym: "NCBP" EXACT [UniProtKB:Q09161] xref: EMBL:AB209233 xref: EMBL:AL162385 xref: EMBL:AL445531 xref: EMBL:BC001450 xref: EMBL:D32002 xref: EMBL:X80030 xref: HGNC:HGNC:7658 xref: UniGene:Hs.595669 xref: UniGene:Hs.686479 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055805 ! NCBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018725 name: NCK1_human def: "Cytoplasmic protein NCK1 gene" [UniProtKB:P16333] synonym: "NCK" EXACT [UniProtKB:P16333] xref: EMBL:BC006403 xref: EMBL:X17576 xref: HGNC:HGNC:7664 xref: UniGene:Hs.477693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055048 ! NCK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018726 name: NCK2_human def: "Cytoplasmic protein NCK2 gene" [UniProtKB:O43639] xref: EMBL:AF043119 xref: EMBL:AF047487 xref: EMBL:BC000103 xref: EMBL:BC007195 xref: HGNC:HGNC:7665 xref: UniGene:Hs.695241 xref: UniGene:Hs.705602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054506 ! NCK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018727 name: NCM_human def: "Nucampholin homolog gene" [UniProtKB:Q9HCG8] synonym: "KIAA1604" EXACT [UniProtKB:Q9HCG8] xref: EMBL:AB046824 xref: EMBL:AK025635 xref: EMBL:AK026978 xref: EMBL:BC016651 xref: EMBL:BC031216 xref: EMBL:BC053573 xref: EMBL:BC057826 xref: EMBL:BC093952 xref: EMBL:BC093954 xref: UniGene:Hs.311363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058807 ! NCM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018728 name: NCOA1_human def: "Nuclear receptor coactivator 1 gene" [UniProtKB:Q15788] synonym: "SRC1" EXACT [UniProtKB:Q15788] xref: EMBL:AC013459 xref: EMBL:AJ000881 xref: EMBL:AJ000882 xref: EMBL:AY633656 xref: EMBL:BC111533 xref: EMBL:BC111534 xref: EMBL:CH471053 xref: EMBL:EF660499 xref: EMBL:U19179 xref: EMBL:U40396 xref: EMBL:U59302 xref: EMBL:U90661 xref: HGNC:HGNC:7668 xref: UniGene:Hs.699183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056112 ! NCOA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018729 name: NCOA2_human def: "Nuclear receptor coactivator 2 gene" [UniProtKB:Q15596] synonym: "TIF2" EXACT [UniProtKB:Q15596] xref: EMBL:X97674 xref: HGNC:HGNC:7669 xref: UniGene:Hs.446678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056076 ! NCOA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018730 name: NCOA5_human def: "Nuclear receptor coactivator 5 gene" [UniProtKB:Q9HCD5] synonym: "KIAA1637" EXACT [UniProtKB:Q9HCD5] xref: EMBL:AB046857 xref: EMBL:AF230533 xref: EMBL:AF470686 xref: EMBL:AL035662 xref: EMBL:AL162458 xref: HGNC:HGNC:15909 xref: UniGene:Hs.654991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058802 ! NCOA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018731 name: NCOR1_human def: "Nuclear receptor corepressor 1 gene" [UniProtKB:O75376] synonym: "KIAA1047" EXACT [UniProtKB:O75376] xref: EMBL:AB019524 xref: EMBL:AB028970 xref: EMBL:AF044209 xref: HGNC:HGNC:7672 xref: UniGene:Hs.462323 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054626 ! NCOR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018732 name: NCR1_human def: "Natural cytotoxicity triggering receptor 1 precursor gene" [UniProtKB:O76036] synonym: "LY94" EXACT [UniProtKB:O76036] xref: EMBL:AJ001383 xref: EMBL:AJ006121 xref: EMBL:AJ006122 xref: EMBL:AJ006123 xref: EMBL:AY346373 xref: EMBL:BC064806 xref: HGNC:HGNC:6731 xref: UniGene:Hs.97084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054688 ! NCTR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018733 name: NCR2_human def: "Natural cytotoxicity triggering receptor 2 precursor gene" [UniProtKB:O95944] synonym: "LY95" EXACT [UniProtKB:O95944] xref: EMBL:AJ010099 xref: EMBL:AJ010100 xref: EMBL:AJ225109 xref: EMBL:AL136967 xref: HGNC:HGNC:6732 xref: UniGene:Hs.194721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054807 ! NCTR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018734 name: NEUROD1_human def: "Neurogenic differentiation factor 1 gene" [UniProtKB:Q13562] synonym: "NEUROD" EXACT [UniProtKB:Q13562] xref: EMBL:AB009997 xref: EMBL:AB016079 xref: EMBL:AB018693 xref: EMBL:AC013733 xref: EMBL:AF045152 xref: EMBL:BC009046 xref: EMBL:BT019731 xref: EMBL:D82347 xref: EMBL:U36472 xref: EMBL:U50822 xref: EMBL:U80578 xref: HGNC:HGNC:7762 xref: UniGene:Hs.440955 xref: UniGene:Hs.574626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055929 ! NDF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018735 name: NEUROD2_human def: "Neurogenic differentiation factor 2 gene" [UniProtKB:Q15784] synonym: "NDRF" EXACT [UniProtKB:Q15784] xref: EMBL:AB021742 xref: EMBL:BC022481 xref: EMBL:U58681 xref: HGNC:HGNC:7763 xref: UniGene:Hs.322431 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056111 ! NDF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018736 name: NEUROD4_human def: "Neurogenic differentiation factor 4 gene" [UniProtKB:Q9HD90] synonym: "ATH3" EXACT [UniProtKB:Q9HD90] synonym: "ATOH3" EXACT [UniProtKB:Q9HD90] xref: EMBL:AF203901 xref: HGNC:HGNC:13802 xref: UniGene:Hs.591024 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058828 ! NDF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018737 name: NEUROD6_human def: "Neurogenic differentiation factor 6 gene" [UniProtKB:Q96NK8] synonym: "ATOH2" EXACT [UniProtKB:Q96NK8] synonym: "My051" EXACT [UniProtKB:Q96NK8] xref: EMBL:AF063609 xref: EMBL:AK055238 xref: HGNC:HGNC:13804 xref: UniGene:Hs.45152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058308 ! NDF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018738 name: NME5_human def: "Nucleoside diphosphate kinase homolog 5 gene" [UniProtKB:P56597] xref: EMBL:AF067724 xref: EMBL:BC026182 xref: EMBL:U90450 xref: EMBL:Y14992 xref: HGNC:HGNC:7853 xref: UniGene:Hs.519602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055546 ! NDK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018739 name: NME6_human def: "Nucleoside diphosphate kinase 6 gene" [UniProtKB:O75414] xref: EMBL:AF051941 xref: EMBL:BC001808 xref: EMBL:BC012828 xref: EMBL:U90449 xref: HGNC:HGNC:20567 xref: UniGene:Hs.465558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054632 ! NDK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018740 name: NDP_human def: "Norrin precursor gene" [UniProtKB:Q00604] synonym: "EVR2" EXACT [UniProtKB:Q00604] xref: EMBL:AL034370 xref: EMBL:BC029901 xref: EMBL:X65724 xref: EMBL:X65882 xref: HGNC:HGNC:7678 xref: UniGene:Hs.522615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055681 ! NDP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018741 name: NDRG3_human def: "Protein NDRG3 gene" [UniProtKB:Q9UGV2] xref: EMBL:AB044943 xref: EMBL:AF251054 xref: EMBL:AF308609 xref: EMBL:AK023618 xref: EMBL:AK027665 xref: EMBL:AL031662 xref: EMBL:AL132768 xref: HGNC:HGNC:14462 xref: UniGene:Hs.437338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059128 ! NDRG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018742 name: NDST2_human def: "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 gene" [UniProtKB:P52849] synonym: "HSST2" EXACT [UniProtKB:P52849] xref: EMBL:AB208870 xref: EMBL:AF042084 xref: EMBL:BC035711 xref: EMBL:BC110588 xref: EMBL:BC110589 xref: EMBL:U36601 xref: HGNC:HGNC:7681 xref: UniGene:Hs.654758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055504 ! NDST2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018743 name: NDUFA13_human def: "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 gene" [UniProtKB:Q9P0J0] synonym: "CDA016" EXACT [UniProtKB:Q9P0J0] synonym: "CGI-39" EXACT [UniProtKB:Q9P0J0] synonym: "GRIM19" EXACT [UniProtKB:Q9P0J0] xref: EMBL:AF132973 xref: EMBL:AF155662 xref: EMBL:AF261134 xref: EMBL:AF286697 xref: EMBL:BC000589 xref: EMBL:BC009189 xref: HGNC:HGNC:17194 xref: UniGene:Hs.534453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059028 ! NDUAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018744 name: NDUFS3_human def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor gene" [UniProtKB:O75489] xref: EMBL:AF067139 xref: EMBL:AF100743 xref: EMBL:AF200954 xref: EMBL:BC000617 xref: HGNC:HGNC:7710 xref: UniGene:Hs.502528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054644 ! NDUS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018745 name: NDUFS4_human def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial precursor gene" [UniProtKB:O43181] xref: EMBL:AF020351 xref: EMBL:BC005270 xref: HGNC:HGNC:7711 xref: UniGene:Hs.528222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054454 ! NDUS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018746 name: NEBL_human def: "Nebulette gene" [UniProtKB:O76041] xref: EMBL:AF047368 xref: EMBL:AL157398 xref: EMBL:BC110453 xref: EMBL:Y16241 xref: EMBL:Y17673 xref: HGNC:HGNC:16932 xref: UniGene:Hs.5025 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054689 ! NEBL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018747 name: NEB_human def: "Nebulin gene" [UniProtKB:P20929] xref: EMBL:AC009497 xref: EMBL:AC107052 xref: EMBL:AC116650 xref: EMBL:M19669 xref: EMBL:X83957 xref: HGNC:HGNC:7720 xref: UniGene:Hs.588655 xref: UniGene:Hs.654592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055127 ! NEBU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018748 name: NECAB3_human def: "N-terminal EF-hand calcium-binding protein 3 gene" [UniProtKB:Q96P71] synonym: "APBA2BP" EXACT [UniProtKB:Q96P71] synonym: "NIP1" EXACT [UniProtKB:Q96P71] synonym: "SYTIP2" EXACT [UniProtKB:Q96P71] synonym: "XB51" EXACT [UniProtKB:Q96P71] xref: EMBL:AB039947 xref: EMBL:AF193759 xref: EMBL:AF409141 xref: EMBL:AK023706 xref: EMBL:AL121906 xref: EMBL:BC047673 xref: HGNC:HGNC:15851 xref: UniGene:Hs.516986 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058325 ! NECA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018749 name: WHSC2_human def: "Negative elongation factor A gene" [UniProtKB:Q9H3P2] synonym: "NELFA" EXACT [UniProtKB:Q9H3P2] synonym: "P/OKcl.15" EXACT [UniProtKB:Q9H3P2] xref: EMBL:AB044549 xref: EMBL:AF101434 xref: EMBL:AF131751 xref: EMBL:AK126056 xref: EMBL:AL132868 xref: EMBL:BC002764 xref: EMBL:CH471131 xref: HGNC:HGNC:12768 xref: UniGene:Hs.21771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058707 ! NELFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018750 name: COBRA1_human def: "Negative elongation factor B gene" [UniProtKB:Q8WX92] synonym: "KIAA1182" EXACT [UniProtKB:Q8WX92] synonym: "NELFB" EXACT [UniProtKB:Q8WX92] xref: EMBL:AB033008 xref: EMBL:AF464935 xref: EMBL:AK022651 xref: EMBL:AL050280 xref: EMBL:BC011892 xref: HGNC:HGNC:24324 xref: UniGene:Hs.655043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058011 ! NELFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018751 name: TH1L_human def: "Negative elongation factor C/D gene" [UniProtKB:Q8IXH7] synonym: "HSPC130" EXACT [UniProtKB:Q8IXH7] synonym: "NELFD" EXACT [UniProtKB:Q8IXH7] synonym: "TH1" EXACT [UniProtKB:Q8IXH7] xref: EMBL:AF161479 xref: EMBL:AJ238374 xref: EMBL:AJ238375 xref: EMBL:AJ238379 xref: EMBL:AK001316 xref: EMBL:AK023310 xref: EMBL:AK023927 xref: EMBL:AK127431 xref: EMBL:AL109840 xref: EMBL:BC014952 xref: HGNC:HGNC:15934 xref: UniGene:Hs.517148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057376 ! NELFD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018752 name: RDBP_human def: "Negative elongation factor E gene" [UniProtKB:P18615] synonym: "NELFE" EXACT [UniProtKB:P18615] synonym: "RD" EXACT [UniProtKB:P18615] xref: EMBL:AF019413 xref: EMBL:AL049547 xref: EMBL:AL662849 xref: EMBL:AL844853 xref: EMBL:BC025235 xref: EMBL:BC050617 xref: EMBL:L03411 xref: EMBL:M32274 xref: EMBL:M32275 xref: EMBL:M32276 xref: EMBL:M33230 xref: EMBL:M33231 xref: EMBL:X16105 xref: HGNC:HGNC:13974 xref: UniGene:Hs.423935 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055102 ! NELFE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018753 name: NENF_human def: "Neudesin precursor gene" [UniProtKB:Q9UMX5] synonym: "CIR2" EXACT [UniProtKB:Q9UMX5] synonym: "SPUF" EXACT [UniProtKB:Q9UMX5] xref: EMBL:AB126219 xref: EMBL:AF173937 xref: EMBL:AK223135 xref: EMBL:AY762102 xref: EMBL:BC008823 xref: EMBL:CH471100 xref: HGNC:HGNC:30384 xref: UniGene:Hs.461787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059243 ! NENF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018754 name: NTN1_human def: "Netrin-1 precursor gene" [UniProtKB:O95631] synonym: "NTN1L" EXACT [UniProtKB:O95631] xref: EMBL:U75586 xref: HGNC:HGNC:8029 xref: UniGene:Hs.660885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054777 ! NET1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018755 name: OXT_human def: "Oxytocin-neurophysin 1 precursor gene" [UniProtKB:P01178] synonym: "OT" EXACT [UniProtKB:P01178] xref: EMBL:AL160414 xref: EMBL:AY082910 xref: EMBL:BC069144 xref: EMBL:BC101841 xref: EMBL:BC101843 xref: EMBL:M11186 xref: EMBL:M25650 xref: EMBL:M62611 xref: EMBL:X03173 xref: HGNC:HGNC:8528 xref: UniGene:Hs.113216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017141 ! NEU1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018756 name: AVP_human def: "Vasopressin-neurophysin 2-copeptin precursor gene" [UniProtKB:P01185] synonym: "ARVP" EXACT [UniProtKB:P01185] synonym: "VP" EXACT [UniProtKB:P01185] xref: EMBL:AF031476 xref: EMBL:AL160414 xref: EMBL:BC126196 xref: EMBL:BC126224 xref: EMBL:M11166 xref: EMBL:M25647 xref: EMBL:X03172 xref: EMBL:X62890 xref: EMBL:X62891 xref: HGNC:HGNC:894 xref: UniGene:Hs.89648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017140 ! NEU2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018757 name: NRGN_human def: "Neurogranin gene" [UniProtKB:Q92686] xref: EMBL:AJ317956 xref: EMBL:BC002835 xref: EMBL:BT007325 xref: EMBL:U89165 xref: EMBL:X99075 xref: EMBL:X99076 xref: EMBL:Y09689 xref: EMBL:Y15058 xref: EMBL:Y15059 xref: HGNC:HGNC:8000 xref: UniGene:Hs.524116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058082 ! NEUG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018758 name: NEURL2_human def: "Neuralized-like protein 2 gene" [UniProtKB:Q9BR09] synonym: "C20orf163" EXACT [UniProtKB:Q9BR09] xref: EMBL:AJ295985 xref: EMBL:AK054821 xref: EMBL:AL008726 xref: EMBL:BC074737 xref: EMBL:BC105935 xref: EMBL:BC107485 xref: HGNC:HGNC:16156 xref: UniGene:Hs.517094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058484 ! NEUL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018759 name: GAP43_human def: "Neuromodulin gene" [UniProtKB:P17677] xref: EMBL:AY842481 xref: EMBL:BC007936 xref: EMBL:M25667 xref: EMBL:S66533 xref: EMBL:S66534 xref: EMBL:S66541 xref: HGNC:HGNC:4140 xref: UniGene:Hs.134974 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055091 ! NEUM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018760 name: NTS_human def: "Neurotensin/neuromedin N precursor gene" [UniProtKB:P30990] xref: EMBL:BC010918 xref: EMBL:S47339 xref: EMBL:U91618 xref: HGNC:HGNC:8038 xref: UniGene:Hs.80962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055232 ! NEUT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018761 name: NEXN_human def: "Nexilin gene" [UniProtKB:Q0ZGT2] xref: EMBL:AF114264 xref: EMBL:AK057954 xref: EMBL:BC017827 xref: EMBL:BC055084 xref: EMBL:BC111395 xref: EMBL:BC114444 xref: EMBL:BC114445 xref: EMBL:DQ464902 xref: EMBL:S67069 xref: HGNC:HGNC:29557 xref: UniGene:Hs.632387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055833 ! NEXN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018762 name: NFATC2IP_human def: "NFATC2-interacting protein gene" [UniProtKB:Q8NCF5] synonym: "NIP45" EXACT [UniProtKB:Q8NCF5] xref: EMBL:AF458593 xref: EMBL:AK027545 xref: EMBL:AK074761 xref: EMBL:BC018311 xref: EMBL:BC021551 xref: EMBL:BC068007 xref: EMBL:BC080628 xref: EMBL:BC101741 xref: EMBL:BC112182 xref: HGNC:HGNC:25906 xref: UniGene:Hs.513470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057565 ! NF2IP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018763 name: NFE2L2_human def: "Nuclear factor erythroid 2-related factor 2 gene" [UniProtKB:Q16236] synonym: "NRF2" EXACT [UniProtKB:Q16236] xref: EMBL:AB208786 xref: EMBL:AC079305 xref: EMBL:AL135266 xref: EMBL:BC011558 xref: EMBL:S74017 xref: HGNC:HGNC:7782 xref: UniGene:Hs.155396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056129 ! NF2L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018764 name: NFE2L3_human def: "Nuclear factor erythroid 2-related factor 3 gene" [UniProtKB:Q9Y4A8] synonym: "NRF3" EXACT [UniProtKB:Q9Y4A8] xref: EMBL:AB010812 xref: EMBL:AC004520 xref: EMBL:AF133059 xref: EMBL:AF134891 xref: EMBL:AF135116 xref: EMBL:BC049219 xref: EMBL:BC056142 xref: EMBL:BC068455 xref: HGNC:HGNC:7783 xref: UniGene:Hs.404741 xref: UniGene:Hs.702899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059355 ! NF2L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018765 name: NFATC1_human def: "Nuclear factor of activated T-cells, cytoplasmic 1 gene" [UniProtKB:O95644] synonym: "NFAT2" EXACT [UniProtKB:O95644] synonym: "NFATC" EXACT [UniProtKB:O95644] xref: EMBL:U08015 xref: EMBL:U59736 xref: EMBL:U80917 xref: EMBL:U80918 xref: EMBL:U80919 xref: HGNC:HGNC:7775 xref: UniGene:Hs.534074 xref: UniGene:Hs.701518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054779 ! NFAC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018766 name: NFATC2_human def: "Nuclear factor of activated T-cells, cytoplasmic 2 gene" [UniProtKB:Q13469] synonym: "NFAT1" EXACT [UniProtKB:Q13469] synonym: "NFATP" EXACT [UniProtKB:Q13469] xref: EMBL:AL035682 xref: EMBL:AL035684 xref: EMBL:AL132866 xref: EMBL:U43341 xref: EMBL:U43342 xref: HGNC:HGNC:7776 xref: UniGene:Hs.699441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055911 ! NFAC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018767 name: NFATC3_human def: "Nuclear factor of activated T-cells, cytoplasmic 3 gene" [UniProtKB:Q12968] synonym: "NFAT4" EXACT [UniProtKB:Q12968] xref: EMBL:AC130462 xref: EMBL:BC001050 xref: EMBL:L41067 xref: EMBL:U14510 xref: EMBL:U85428 xref: EMBL:U85429 xref: EMBL:U85430 xref: HGNC:HGNC:7777 xref: UniGene:Hs.632209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055859 ! NFAC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018768 name: NFATC4_human def: "Nuclear factor of activated T-cells, cytoplasmic 4 gene" [UniProtKB:Q14934] synonym: "NFAT3" EXACT [UniProtKB:Q14934] xref: EMBL:BC053855 xref: EMBL:EU887641 xref: EMBL:L41066 xref: HGNC:HGNC:7778 xref: UniGene:Hs.77810 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056026 ! NFAC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018769 name: NFAM1_human def: "NFAT activation molecule 1 precursor gene" [UniProtKB:Q8NET5] synonym: "CNAIP" EXACT [UniProtKB:Q8NET5] xref: EMBL:AK074094 xref: EMBL:AL022316 xref: EMBL:AY121370 xref: EMBL:AY247409 xref: EMBL:BC038241 xref: EMBL:CH471095 xref: EMBL:CT841509 xref: HGNC:HGNC:29872 xref: UniGene:Hs.436677 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057595 ! NFAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018770 name: NFAT5_human def: "Nuclear factor of activated T-cells 5 gene" [UniProtKB:O94916] synonym: "KIAA0827" EXACT [UniProtKB:O94916] synonym: "TONEBP" EXACT [UniProtKB:O94916] xref: EMBL:AB020634 xref: EMBL:AF089824 xref: EMBL:AF134870 xref: EMBL:AF163836 xref: EMBL:BC131509 xref: EMBL:Z97016 xref: HGNC:HGNC:7774 xref: UniGene:Hs.371987 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053735 ! A2RRB4_HUMAN relationship: codes_for CCO:B0054712 ! NFAT5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018771 name: NFE2_human def: "Transcription factor NF-E2 45 kDa subunit gene" [UniProtKB:Q16621] xref: EMBL:BC005044 xref: EMBL:BT007288 xref: EMBL:CR450284 xref: EMBL:DQ367844 xref: EMBL:L13974 xref: EMBL:L24122 xref: EMBL:S77763 xref: HGNC:HGNC:7780 xref: UniGene:Hs.75643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056162 ! NFE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018772 name: NFIA_human def: "Nuclear factor 1 A-type gene" [UniProtKB:Q12857] synonym: "KIAA1439" EXACT [UniProtKB:Q12857] xref: EMBL:AB037860 xref: EMBL:AC096534 xref: EMBL:AC099792 xref: EMBL:AL096888 xref: EMBL:AL445198 xref: EMBL:BC022264 xref: EMBL:CH471059 xref: EMBL:U07809 xref: HGNC:HGNC:7784 xref: UniGene:Hs.191911 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025416 ! NFIA_HUMAN relationship: codes_for CCO:B0025417 ! Q8TA97_HUMAN relationship: codes_for CCO:B0054228 ! B1AKN5_HUMAN relationship: codes_for CCO:B0054229 ! B1AKN6_HUMAN relationship: codes_for CCO:B0054230 ! B1AKN7_HUMAN relationship: codes_for CCO:B0054231 ! B1AKN8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018773 name: NFIB_human def: "Nuclear factor 1 B-type gene" [UniProtKB:O00712] xref: EMBL:AL136366 xref: EMBL:AL441963 xref: EMBL:BC001283 xref: EMBL:BT007266 xref: EMBL:CH471071 xref: EMBL:U07810 xref: EMBL:U70862 xref: EMBL:U85193 xref: HGNC:HGNC:7785 xref: UniGene:Hs.644095 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025410 ! Q5W0Y9_HUMAN relationship: codes_for CCO:B0025414 ! NFIB_HUMAN relationship: codes_for CCO:B0025421 ! Q5VW27_HUMAN relationship: codes_for CCO:B0025423 ! Q5VW31_HUMAN relationship: codes_for CCO:B0025428 ! Q5VW30_HUMAN relationship: codes_for CCO:B0025429 ! Q5VW29_HUMAN relationship: codes_for CCO:B0025430 ! Q5VW26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018774 name: NFIC_human def: "Nuclear factor 1 C-type gene" [UniProtKB:P08651] synonym: "NFI" EXACT [UniProtKB:P08651] xref: EMBL:AC005514 xref: EMBL:AC005551 xref: EMBL:AC005778 xref: EMBL:BC012120 xref: EMBL:X12492 xref: EMBL:X92857 xref: HGNC:HGNC:7786 xref: UniGene:Hs.170131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025412 ! NFIC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018775 name: NFIL3_human def: "Nuclear factor interleukin-3-regulated protein gene" [UniProtKB:Q16649] synonym: "E4BP4" EXACT [UniProtKB:Q16649] synonym: "IL3BP1" EXACT [UniProtKB:Q16649] xref: EMBL:AL353764 xref: EMBL:BC008197 xref: EMBL:CR542049 xref: EMBL:EF028070 xref: EMBL:S79880 xref: EMBL:U26173 xref: EMBL:X64318 xref: HGNC:HGNC:7787 xref: UniGene:Hs.79334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056167 ! NFIL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018776 name: NDFIP1_human def: "NEDD4 family-interacting protein 1 gene" [UniProtKB:Q9BT67] synonym: "N4WBP5" EXACT [UniProtKB:Q9BT67] synonym: "PSEC0192" EXACT [UniProtKB:Q9BT67] synonym: "PSEC0223" EXACT [UniProtKB:Q9BT67] xref: EMBL:AB097010 xref: EMBL:AB097037 xref: EMBL:AK075495 xref: EMBL:AK075524 xref: EMBL:AL832993 xref: EMBL:AY192728 xref: EMBL:BC004317 xref: HGNC:HGNC:17592 xref: UniGene:Hs.9788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058512 ! NFIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018777 name: NDFIP2_human def: "NEDD4 family-interacting protein 2 gene" [UniProtKB:Q9NV92] synonym: "KIAA1165" EXACT [UniProtKB:Q9NV92] synonym: "N4WBP5A" EXACT [UniProtKB:Q9NV92] xref: EMBL:AB032991 xref: EMBL:AB097019 xref: EMBL:AB097028 xref: EMBL:AB097029 xref: EMBL:AB097030 xref: EMBL:AB097031 xref: EMBL:AK001723 xref: EMBL:AL136442 xref: EMBL:AL355603 xref: EMBL:BC021988 xref: EMBL:BC026126 xref: HGNC:HGNC:18537 xref: UniGene:Hs.525093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058930 ! NFIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018778 name: NFIX_human def: "Nuclear factor 1 X-type gene" [UniProtKB:Q14938] xref: EMBL:AC004660 xref: EMBL:AC007787 xref: EMBL:L31881 xref: EMBL:U07811 xref: EMBL:U18759 xref: EMBL:U18761 xref: HGNC:HGNC:7788 xref: UniGene:Hs.257970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025407 ! NFIX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018779 name: NFKB1_human def: "Nuclear factor NF-kappa-B p105 subunit gene" [UniProtKB:P19838] xref: EMBL:AF213884 xref: EMBL:AY223820 xref: EMBL:BC033210 xref: EMBL:BC051765 xref: EMBL:CR749522 xref: EMBL:M55643 xref: EMBL:M58603 xref: EMBL:Z47734 xref: EMBL:Z47735 xref: EMBL:Z47736 xref: EMBL:Z47737 xref: EMBL:Z47738 xref: EMBL:Z47739 xref: EMBL:Z47740 xref: EMBL:Z47741 xref: EMBL:Z47742 xref: EMBL:Z47743 xref: EMBL:Z47744 xref: EMBL:Z47748 xref: EMBL:Z47749 xref: EMBL:Z47750 xref: EMBL:Z47751 xref: EMBL:Z47752 xref: EMBL:Z47753 xref: EMBL:Z47754 xref: EMBL:Z47755 xref: HGNC:HGNC:7794 xref: UniGene:Hs.654408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055110 ! NFKB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018780 name: NEFM_human def: "Neurofilament medium polypeptide gene" [UniProtKB:P07197] synonym: "NEF3" EXACT [UniProtKB:P07197] synonym: "NFM" EXACT [UniProtKB:P07197] xref: EMBL:Y00067 xref: HGNC:HGNC:7734 xref: UniGene:Hs.458657 xref: UniGene:Hs.615287 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054909 ! NFM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018781 name: NFX1_human def: "Transcriptional repressor NF-X1 gene" [UniProtKB:Q12986] synonym: "NFX2" EXACT [UniProtKB:Q12986] xref: EMBL:AF332009 xref: EMBL:AK291643 xref: EMBL:AL356218 xref: EMBL:AL356472 xref: EMBL:BC012151 xref: EMBL:CH471071 xref: EMBL:U15306 xref: HGNC:HGNC:7803 xref: UniGene:Hs.413074 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055863 ! NFX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018782 name: NFXL1_human def: "NF-X1-type zinc finger protein NFXL1 gene" [UniProtKB:Q6ZNB6] synonym: "OZFP" EXACT [UniProtKB:Q6ZNB6] xref: EMBL:AC107068 xref: EMBL:AK131285 xref: EMBL:BC018019 xref: EMBL:BC051193 xref: HGNC:HGNC:18726 xref: UniGene:Hs.646325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057019 ! NFXL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018783 name: NGDN_human def: "Neuroguidin gene" [UniProtKB:Q8NEJ9] synonym: "C14orf120" EXACT [UniProtKB:Q8NEJ9] xref: EMBL:AL050003 xref: EMBL:BC030817 xref: HGNC:HGNC:20271 xref: UniGene:Hs.9043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057591 ! NGDN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018784 name: NGEF_human def: "Ephexin-1 gene" [UniProtKB:Q8N5V2] xref: EMBL:AC016692 xref: EMBL:AC106876 xref: EMBL:AJ238899 xref: EMBL:BC031573 xref: EMBL:BC073962 xref: HGNC:HGNC:7807 xref: UniGene:Hs.97316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057480 ! NGEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018785 name: NGF_human def: "Beta-nerve growth factor precursor gene" [UniProtKB:P01138] synonym: "NGFB" EXACT [UniProtKB:P01138] xref: EMBL:AB037517 xref: EMBL:AF150960 xref: EMBL:AF411526 xref: EMBL:AL049825 xref: EMBL:BC032517 xref: EMBL:BT019733 xref: EMBL:CR541855 xref: EMBL:M21062 xref: EMBL:V01511 xref: EMBL:X52599 xref: HGNC:HGNC:7808 xref: UniGene:Hs.2561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054834 ! NGF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018786 name: LRRC4C_human def: "Netrin-G1 ligand precursor gene" [UniProtKB:Q9HCJ2] synonym: "KIAA1580" EXACT [UniProtKB:Q9HCJ2] synonym: "NGL1" EXACT [UniProtKB:Q9HCJ2] synonym: "UNQ292/PRO331" EXACT [UniProtKB:Q9HCJ2] xref: EMBL:AB046800 xref: EMBL:AY358293 xref: EMBL:BC041374 xref: HGNC:HGNC:29317 xref: UniGene:Hs.135736 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058808 ! NGL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018787 name: SLC9A3R1_human def: "Ezrin-radixin-moesin-binding phosphoprotein 50 gene" [UniProtKB:O14745] synonym: "NHERF" EXACT [UniProtKB:O14745] xref: EMBL:AF015926 xref: EMBL:AF036241 xref: EMBL:BC001443 xref: EMBL:BC003361 xref: EMBL:BC011777 xref: EMBL:BC049220 xref: EMBL:BC053350 xref: HGNC:HGNC:11075 xref: UniGene:Hs.396783 xref: UniGene:Hs.699203 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025071 ! NHERF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018788 name: NCSTN_human def: "Nicastrin precursor gene" [UniProtKB:Q92542] synonym: "KIAA0253" EXACT [UniProtKB:Q92542] synonym: "UNQ1874/PRO4317" EXACT [UniProtKB:Q92542] xref: EMBL:AF240468 xref: EMBL:AY359120 xref: EMBL:BC047621 xref: EMBL:D87442 xref: HGNC:HGNC:17091 xref: UniGene:Hs.517249 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058062 ! NICA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018789 name: NKD1_human def: "Protein naked cuticle homolog 1 gene" [UniProtKB:Q969G9] synonym: "NKD" EXACT [UniProtKB:Q969G9] synonym: "PP7246" EXACT [UniProtKB:Q969G9] xref: EMBL:AB062886 xref: EMBL:AF289584 xref: EMBL:AF358135 xref: EMBL:AY061883 xref: EMBL:BC051288 xref: HGNC:HGNC:17045 xref: UniGene:Hs.592059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058130 ! NKD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018790 name: NKD2_human def: "Protein naked cuticle homolog 2 gene" [UniProtKB:Q969F2] xref: EMBL:AB062887 xref: EMBL:AF358137 xref: EMBL:BC004940 xref: EMBL:BC012176 xref: HGNC:HGNC:17046 xref: UniGene:Hs.240951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058128 ! NKD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018791 name: KLRK1_human def: "NKG2-D type II integral membrane protein gene" [UniProtKB:P26718] synonym: "D12S2489E" EXACT [UniProtKB:P26718] synonym: "NKG2D" EXACT [UniProtKB:P26718] xref: EMBL:AC022075 xref: EMBL:AF260135 xref: EMBL:AF260136 xref: EMBL:AF461811 xref: EMBL:AJ001687 xref: EMBL:AJ001688 xref: EMBL:AJ001689 xref: EMBL:BC039836 xref: EMBL:X54870 xref: HGNC:HGNC:18788 xref: UniGene:Hs.387787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055192 ! NKG2D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018792 name: NKX1-1_human def: "NK1 transcription factor-related protein 1 gene" [UniProtKB:Q15270] synonym: "HPX153" EXACT [UniProtKB:Q15270] xref: EMBL:AC118281 xref: EMBL:X76978 xref: HGNC:HGNC:24975 xref: UniGene:Hs.526396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056051 ! NKX11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018793 name: NKX1-2_human def: "NK1 transcription factor-related protein 2 gene" [UniProtKB:Q9UD57] synonym: "C10orf121" EXACT [UniProtKB:Q9UD57] synonym: "NKX1.1" EXACT [UniProtKB:Q9UD57] xref: EMBL:AL445237 xref: HGNC:HGNC:31652 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059098 ! NKX12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018794 name: NKX2-1_human def: "Homeobox protein Nkx-2.1 gene" [UniProtKB:P43699] synonym: "NKX2A" EXACT [UniProtKB:P43699] synonym: "TITF1" EXACT [UniProtKB:P43699] synonym: "TTF1" EXACT [UniProtKB:P43699] xref: EMBL:BC006221 xref: EMBL:D50739 xref: EMBL:D50740 xref: EMBL:U19756 xref: EMBL:U19816 xref: EMBL:U33749 xref: EMBL:U43203 xref: EMBL:X82850 xref: HGNC:HGNC:11825 xref: UniGene:Hs.705388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055370 ! NKX21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018795 name: NKX2-2_human def: "Homeobox protein Nkx-2.2 gene" [UniProtKB:O95096] synonym: "NKX2.2" EXACT [UniProtKB:O95096] synonym: "NKX2B" EXACT [UniProtKB:O95096] xref: EMBL:AF019414 xref: EMBL:AF019415 xref: EMBL:AL133325 xref: EMBL:BC075092 xref: EMBL:BC075093 xref: HGNC:HGNC:7835 xref: UniGene:Hs.516922 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054723 ! NKX22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018796 name: NKX2-3_human def: "Homeobox protein Nkx-2.3 gene" [UniProtKB:Q8TAU0] synonym: "NKX23" EXACT [UniProtKB:Q8TAU0] synonym: "NKX2C" EXACT [UniProtKB:Q8TAU0] xref: EMBL:AF229630 xref: EMBL:AF229631 xref: EMBL:AL353719 xref: EMBL:BC025788 xref: HGNC:HGNC:7836 xref: UniGene:Hs.243272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057892 ! NKX23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018797 name: NKX2-5_human def: "Homeobox protein Nkx-2.5 gene" [UniProtKB:P52952] synonym: "CSX" EXACT [UniProtKB:P52952] synonym: "NKX2.5" EXACT [UniProtKB:P52952] synonym: "NKX2E" EXACT [UniProtKB:P52952] xref: EMBL:AB021133 xref: EMBL:BC025711 xref: EMBL:EF122296 xref: EMBL:EF122297 xref: EMBL:EF122298 xref: EMBL:EF122299 xref: EMBL:EF122300 xref: EMBL:EF122306 xref: EMBL:EF122307 xref: EMBL:EF122319 xref: EMBL:EF122325 xref: EMBL:EF122331 xref: EMBL:EF122336 xref: EMBL:U34962 xref: HGNC:HGNC:2488 xref: UniGene:Hs.54473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053708 ! A1ECB1_HUMAN relationship: codes_for CCO:B0053709 ! A1ECB2_HUMAN relationship: codes_for CCO:B0055506 ! NKX25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018798 name: NKX2-6_human def: "Homeobox protein Nkx-2.6 gene" [UniProtKB:A6NCS4] synonym: "NKX2F" EXACT [UniProtKB:A6NCS4] xref: EMBL:AC012574 xref: HGNC:HGNC:32940 xref: UniGene:Hs.532654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053785 ! NKX26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018799 name: NKX2-8_human def: "Homeobox protein Nkx-2.8 gene" [UniProtKB:O15522] synonym: "NKX-2.8" EXACT [UniProtKB:O15522] synonym: "NKX2G" EXACT [UniProtKB:O15522] synonym: "NKX2H" EXACT [UniProtKB:O15522] xref: EMBL:AF000295 xref: EMBL:AF000296 xref: EMBL:AF000297 xref: EMBL:AK313537 xref: EMBL:BC041090 xref: HGNC:HGNC:16364 xref: UniGene:Hs.234763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032527 ! NKX28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018800 name: NKX3-1_human def: "Homeobox protein Nkx-3.1 gene" [UniProtKB:Q99801] synonym: "NKX3.1" EXACT [UniProtKB:Q99801] synonym: "NKX3A" EXACT [UniProtKB:Q99801] xref: EMBL:AF247704 xref: EMBL:AF249669 xref: EMBL:AF249670 xref: EMBL:AF249671 xref: EMBL:AF249672 xref: EMBL:BC074863 xref: EMBL:BC074864 xref: EMBL:U80669 xref: EMBL:U91540 xref: HGNC:HGNC:7838 xref: UniGene:Hs.55999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058455 ! NKX31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018801 name: NKX3-2_human def: "Homeobox protein Nkx-3.2 gene" [UniProtKB:P78367] synonym: "BAPX1" EXACT [UniProtKB:P78367] synonym: "NKX3B" EXACT [UniProtKB:P78367] xref: EMBL:AF005260 xref: EMBL:AF009801 xref: EMBL:AF009802 xref: EMBL:BC111966 xref: EMBL:U89845 xref: HGNC:HGNC:951 xref: UniGene:Hs.590927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055642 ! NKX32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018802 name: NLGN1_human def: "Neuroligin-1 precursor gene" [UniProtKB:Q8N2Q7] synonym: "KIAA1070" EXACT [UniProtKB:Q8N2Q7] xref: EMBL:AB028993 xref: EMBL:AC008082 xref: EMBL:AC008120 xref: EMBL:AC092923 xref: EMBL:AC092967 xref: EMBL:AC110871 xref: EMBL:AC131158 xref: EMBL:AK074522 xref: EMBL:BC032555 xref: HGNC:HGNC:14291 xref: UniGene:Hs.478289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057446 ! NLGN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018803 name: NLK_human def: "Serine/threonine kinase NLK gene" [UniProtKB:Q9UBE8] synonym: "LAK1" EXACT [UniProtKB:Q9UBE8] xref: EMBL:AF180819 xref: EMBL:AF197898 xref: EMBL:BC064663 xref: EMBL:DQ316259 xref: HGNC:HGNC:29858 xref: UniGene:Hs.208759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059070 ! NLK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018804 name: NLRC3_human def: "Protein NLRC3 gene" [UniProtKB:Q7RTR2] synonym: "NOD3" EXACT [UniProtKB:Q7RTR2] xref: EMBL:AF501291 xref: EMBL:AF501292 xref: EMBL:AK074109 xref: EMBL:AK090431 xref: EMBL:AY601811 xref: EMBL:BK001112 xref: HGNC:HGNC:29889 xref: UniGene:Hs.592091 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057124 ! NLRC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018805 name: NLRC4_human def: "NLR family CARD domain-containing protein 4 gene" [UniProtKB:Q9NPP4] synonym: "CARD12" EXACT [UniProtKB:Q9NPP4] synonym: "CLAN" EXACT [UniProtKB:Q9NPP4] synonym: "CLAN1" EXACT [UniProtKB:Q9NPP4] synonym: "IPAF" EXACT [UniProtKB:Q9NPP4] synonym: "UNQ6189/PRO20215" EXACT [UniProtKB:Q9NPP4] xref: EMBL:AF376061 xref: EMBL:AL389934 xref: EMBL:AY027787 xref: EMBL:AY027788 xref: EMBL:AY027789 xref: EMBL:AY027790 xref: EMBL:AY032589 xref: EMBL:AY035391 xref: EMBL:AY358152 xref: EMBL:BC031555 xref: HGNC:HGNC:16412 xref: UniGene:Hs.574741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058856 ! NLRC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018806 name: NMBR_human def: "Neuromedin-B receptor gene" [UniProtKB:P28336] xref: EMBL:AL589674 xref: EMBL:CH471051 xref: EMBL:M73482 xref: HGNC:HGNC:7843 xref: UniGene:Hs.654478 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055201 ! NMBR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018807 name: NMB_human def: "Neuromedin-B precursor gene" [UniProtKB:P08949] xref: EMBL:BC007407 xref: EMBL:BC007431 xref: EMBL:BC008603 xref: EMBL:M21551 xref: HGNC:HGNC:7842 xref: UniGene:Hs.386470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054938 ! NMB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018808 name: GRIN1_human def: "Glutamate [NMDA] receptor subunit zeta-1 precursor gene" [UniProtKB:Q05586] synonym: "NMDAR1" EXACT [UniProtKB:Q05586] xref: EMBL:AL929554 xref: EMBL:D13515 xref: EMBL:L05666 xref: EMBL:L13266 xref: EMBL:L13267 xref: EMBL:L13268 xref: EMBL:S57708 xref: EMBL:U08106 xref: EMBL:U08107 xref: EMBL:Z32772 xref: EMBL:Z32773 xref: EMBL:Z32774 xref: HGNC:HGNC:4584 xref: UniGene:Hs.558334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055744 ! NMDZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018809 name: NMS_human def: "Neuromedin-S precursor gene" [UniProtKB:Q5H8A3] xref: EMBL:AB164464 xref: HGNC:HGNC:32203 xref: UniGene:Hs.567676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056430 ! NMS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018810 name: NMUR1_human def: "Neuromedin-U receptor 1 gene" [UniProtKB:Q9HB89] synonym: "GPR66" EXACT [UniProtKB:Q9HB89] xref: EMBL:AC017104 xref: EMBL:AF044600 xref: EMBL:AF044601 xref: EMBL:AF272362 xref: EMBL:BC036543 xref: EMBL:BC051914 xref: HGNC:HGNC:4518 xref: UniGene:Hs.471619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058780 ! NMUR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018811 name: NMUR2_human def: "Neuromedin-U receptor 2 gene" [UniProtKB:Q9GZQ4] synonym: "NMU2R" EXACT [UniProtKB:Q9GZQ4] synonym: "TGR1" EXACT [UniProtKB:Q9GZQ4] xref: EMBL:AB041228 xref: EMBL:AF242874 xref: EMBL:AF272363 xref: EMBL:AF292402 xref: EMBL:BC016938 xref: EMBL:BC067776 xref: HGNC:HGNC:16454 xref: UniGene:Hs.283093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058632 ! NMUR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018812 name: NMU_human def: "Neuromedin-U precursor gene" [UniProtKB:P48645] xref: EMBL:BC012908 xref: EMBL:X76029 xref: HGNC:HGNC:7859 xref: UniGene:Hs.418367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055409 ! NMU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018813 name: NO66_human def: "Nucleolar protein 66 gene" [UniProtKB:Q9H6W3] synonym: "C14orf169" EXACT [UniProtKB:Q9H6W3] xref: EMBL:AK025455 xref: EMBL:AY390535 xref: EMBL:BC011350 xref: EMBL:BC071954 xref: HGNC:HGNC:20968 xref: UniGene:Hs.509916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058736 ! NO66_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018814 name: NOBOX_human def: "Homeobox protein NOBOX gene" [UniProtKB:O60393] xref: EMBL:AC004534 xref: HGNC:HGNC:22448 xref: UniGene:Hs.558628 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054551 ! NOBOX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018815 name: NOD1_human def: "Nucleotide-binding oligomerization domain-containing protein 1 gene" [UniProtKB:Q9Y239] synonym: "CARD4" EXACT [UniProtKB:Q9Y239] xref: EMBL:AC006027 xref: EMBL:AF113925 xref: EMBL:AF126484 xref: EMBL:AF149774 xref: EMBL:BC040339 xref: HGNC:HGNC:16390 xref: UniGene:Hs.405153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059290 ! NOD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018816 name: NOD2_human def: "Nucleotide-binding oligomerization domain-containing protein 2 gene" [UniProtKB:Q9HC29] synonym: "CARD15" EXACT [UniProtKB:Q9HC29] synonym: "IBD1" EXACT [UniProtKB:Q9HC29] xref: EMBL:AF178930 xref: EMBL:AF385089 xref: EMBL:AF385090 xref: EMBL:AJ303140 xref: HGNC:HGNC:5331 xref: UniGene:Hs.592072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058795 ! NOD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018817 name: NOL3_human def: "Nucleolar protein 3 gene" [UniProtKB:O60936] synonym: "ARC" EXACT [UniProtKB:O60936] synonym: "NOP" EXACT [UniProtKB:O60936] xref: EMBL:AF043244 xref: EMBL:AF064598 xref: EMBL:AF064599 xref: EMBL:AF064600 xref: EMBL:BC012798 xref: HGNC:HGNC:7869 xref: UniGene:Hs.513667 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054591 ! NOL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018818 name: NOL8_human def: "Nucleolar protein 8 gene" [UniProtKB:Q76FK4] synonym: "C9orf34" EXACT [UniProtKB:Q76FK4] synonym: "NOP132" EXACT [UniProtKB:Q76FK4] xref: EMBL:AB105104 xref: EMBL:AB109030 xref: EMBL:AK000743 xref: EMBL:AK001049 xref: EMBL:AK022755 xref: EMBL:AK024245 xref: EMBL:AK024786 xref: EMBL:AL136097 xref: EMBL:BC013788 xref: HGNC:HGNC:23387 xref: UniGene:Hs.442199 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057103 ! NOL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018819 name: NOS3_human def: "Nitric oxide synthase, endothelial gene" [UniProtKB:P29474] xref: EMBL:AF519768 xref: EMBL:BC069465 xref: EMBL:D26607 xref: EMBL:L10693 xref: EMBL:L10694 xref: EMBL:L10695 xref: EMBL:L10696 xref: EMBL:L10697 xref: EMBL:L10698 xref: EMBL:L10699 xref: EMBL:L10700 xref: EMBL:L10701 xref: EMBL:L10702 xref: EMBL:L10703 xref: EMBL:L10704 xref: EMBL:L10705 xref: EMBL:L10706 xref: EMBL:L10707 xref: EMBL:L10708 xref: EMBL:L10709 xref: EMBL:L23210 xref: EMBL:L26914 xref: EMBL:M93718 xref: EMBL:M95296 xref: EMBL:S80791 xref: EMBL:X76303 xref: EMBL:X76304 xref: EMBL:X76305 xref: EMBL:X76306 xref: EMBL:X76307 xref: EMBL:X76308 xref: EMBL:X76309 xref: EMBL:X76310 xref: EMBL:X76311 xref: EMBL:X76312 xref: EMBL:X76313 xref: EMBL:X76314 xref: EMBL:X76315 xref: EMBL:X76316 xref: HGNC:HGNC:7876 xref: UniGene:Hs.699165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055215 ! NOS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018820 name: NOSTRIN_human def: "Nostrin gene" [UniProtKB:Q8IVI9] xref: EMBL:AC009475 xref: EMBL:AC069137 xref: EMBL:AJ532842 xref: EMBL:AK002203 xref: EMBL:AL550371 xref: EMBL:BC014189 xref: EMBL:BC093072 xref: EMBL:DQ402497 xref: HGNC:HGNC:20203 xref: UniGene:Hs.189780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023770 ! NOSTN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018821 name: NOX1_human def: "NADPH oxidase 1 gene" [UniProtKB:Q9Y5S8] synonym: "NOH1" EXACT [UniProtKB:Q9Y5S8] xref: EMBL:AF127763 xref: EMBL:AF166326 xref: EMBL:AF166327 xref: EMBL:AF166328 xref: EMBL:BC075014 xref: EMBL:BC075015 xref: EMBL:DQ314883 xref: EMBL:Z83819 xref: HGNC:HGNC:7889 xref: UniGene:Hs.592227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059386 ! NOX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018822 name: NOX4_human def: "NADPH oxidase 4 gene" [UniProtKB:Q9NPH5] synonym: "RENOX" EXACT [UniProtKB:Q9NPH5] xref: EMBL:AB041035 xref: EMBL:AF254621 xref: EMBL:AF261943 xref: EMBL:AJ704725 xref: EMBL:AJ704726 xref: EMBL:AJ704727 xref: EMBL:AJ704728 xref: EMBL:AJ704729 xref: EMBL:AK291830 xref: EMBL:AP001815 xref: EMBL:AP002404 xref: EMBL:AY288918 xref: EMBL:BC040105 xref: EMBL:BC051371 xref: HGNC:HGNC:7891 xref: UniGene:Hs.371036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058854 ! NOX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018823 name: NOX5_human def: "NADPH oxidase 5 gene" [UniProtKB:Q96PH1] xref: EMBL:AF317889 xref: EMBL:AF325189 xref: EMBL:AF325190 xref: EMBL:AF353088 xref: EMBL:AF353089 xref: EMBL:AK026011 xref: EMBL:AK074058 xref: EMBL:AK074071 xref: EMBL:DQ314884 xref: HGNC:HGNC:14874 xref: UniGene:Hs.657932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058335 ! NOX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018824 name: NOXA1_human def: "NADPH oxidase activator 1 gene" [UniProtKB:Q86UR1] synonym: "P51NOX" EXACT [UniProtKB:Q86UR1] xref: EMBL:AB095031 xref: EMBL:AF039697 xref: EMBL:AY255769 xref: EMBL:AY927790 xref: EMBL:AY927791 xref: EMBL:BC041594 xref: EMBL:BC110840 xref: EMBL:BX322799 xref: HGNC:HGNC:10668 xref: UniGene:Hs.495554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057254 ! NOXA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018825 name: NOXO1_human def: "NADPH oxidase organizer 1 gene" [UniProtKB:Q8NFA2] synonym: "P41NOX" EXACT [UniProtKB:Q8NFA2] synonym: "SH3PXD5" EXACT [UniProtKB:Q8NFA2] xref: EMBL:AB097667 xref: EMBL:AF532983 xref: EMBL:AF532984 xref: EMBL:AF532985 xref: EMBL:AF539796 xref: EMBL:AY191359 xref: EMBL:AY255768 xref: EMBL:BC015917 xref: HGNC:HGNC:19404 xref: UniGene:Hs.191762 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057598 ! NOXO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018826 name: C5orf13_human def: "Neuronal protein 3.1 gene" [UniProtKB:Q16612] synonym: "P311" EXACT [UniProtKB:Q16612] xref: EMBL:BC011050 xref: EMBL:BC019068 xref: EMBL:BC072013 xref: EMBL:BC072443 xref: EMBL:U30521 xref: EMBL:U36189 xref: HGNC:HGNC:16834 xref: UniGene:Hs.36053 xref: UniGene:Hs.483067 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056159 ! NP311_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018827 name: NPAS1_human def: "Neuronal PAS domain-containing protein 1 gene" [UniProtKB:Q99742] synonym: "MOP5" EXACT [UniProtKB:Q99742] xref: EMBL:AB054002 xref: EMBL:BC039016 xref: EMBL:U51628 xref: EMBL:U77968 xref: HGNC:HGNC:7894 xref: UniGene:Hs.79564 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058451 ! NPAS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018828 name: NPAS3_human def: "Neuronal PAS domain-containing protein 3 gene" [UniProtKB:Q8IXF0] synonym: "MOP6" EXACT [UniProtKB:Q8IXF0] xref: EMBL:AB054575 xref: EMBL:AB054576 xref: EMBL:AB055962 xref: EMBL:AF164438 xref: EMBL:AL079281 xref: EMBL:AY157302 xref: EMBL:AY157303 xref: HGNC:HGNC:19311 xref: UniGene:Hs.659456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057375 ! NPAS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018829 name: NPAS4_human def: "Neuronal PAS domain-containing protein 4 gene" [UniProtKB:Q8IUM7] synonym: "NXF" EXACT [UniProtKB:Q8IUM7] xref: EMBL:AB049469 xref: EMBL:AK094025 xref: EMBL:AK096253 xref: EMBL:BC105001 xref: EMBL:BC105003 xref: HGNC:HGNC:18983 xref: UniGene:Hs.256036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057325 ! NPAS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018830 name: NPB_human def: "Neuropeptide B precursor gene" [UniProtKB:Q8NG41] synonym: "PPL7" EXACT [UniProtKB:Q8NG41] synonym: "PPNPB" EXACT [UniProtKB:Q8NG41] xref: EMBL:AB085942 xref: EMBL:AF525737 xref: EMBL:AF525738 xref: EMBL:AL360181 xref: EMBL:BC126128 xref: EMBL:BC126485 xref: HGNC:HGNC:30099 xref: UniGene:Hs.585089 xref: UniGene:Hs.700354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057612 ! NPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018831 name: NPC2_human def: "Epididymal secretory protein E1 precursor gene" [UniProtKB:P61916] xref: EMBL:BC002532 xref: EMBL:X67698 xref: HGNC:HGNC:14537 xref: UniGene:Hs.433222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055613 ! NPC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018832 name: NPFFR1_human def: "Neuropeptide FF receptor 1 gene" [UniProtKB:Q9GZQ6] synonym: "GPR147" EXACT [UniProtKB:Q9GZQ6] synonym: "NPFF1" EXACT [UniProtKB:Q9GZQ6] xref: EMBL:AB040104 xref: EMBL:AB065729 xref: EMBL:AF268898 xref: EMBL:AF330055 xref: HGNC:HGNC:17425 xref: UniGene:Hs.302026 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058633 ! NPFF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018833 name: NPFFR2_human def: "Neuropeptide FF receptor 2 gene" [UniProtKB:Q9Y5X5] synonym: "GPR74" EXACT [UniProtKB:Q9Y5X5] synonym: "NPFF2" EXACT [UniProtKB:Q9Y5X5] synonym: "NPGPR" EXACT [UniProtKB:Q9Y5X5] xref: EMBL:AF119815 xref: EMBL:AF236083 xref: EMBL:AF257210 xref: EMBL:AF268899 xref: EMBL:AF330053 xref: EMBL:AJ311393 xref: HGNC:HGNC:4525 xref: UniGene:Hs.99231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059392 ! NPFF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018834 name: NPFF_human def: "FMRFamide-related peptides precursor gene" [UniProtKB:O15130] xref: EMBL:AF005271 xref: EMBL:BC104234 xref: EMBL:BC104235 xref: EMBL:CH471054 xref: HGNC:HGNC:7901 xref: UniGene:Hs.104555 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054409 ! NPFF_HUMAN relationship: codes_for CCO:B0056268 ! Q3SXL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018835 name: NPHP1_human def: "Nephrocystin-1 gene" [UniProtKB:O15259] synonym: "NPH1" EXACT [UniProtKB:O15259] xref: EMBL:AF023674 xref: EMBL:AJ001815 xref: EMBL:BC009789 xref: EMBL:BC062574 xref: HGNC:HGNC:7905 xref: UniGene:Hs.280388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054420 ! NPHP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018836 name: NPHP3_human def: "Nephrocystin-3 gene" [UniProtKB:Q7Z494] synonym: "KIAA2000" EXACT [UniProtKB:Q7Z494] xref: EMBL:AB082531 xref: EMBL:AK055253 xref: EMBL:AK055893 xref: EMBL:AK094015 xref: EMBL:AL832863 xref: EMBL:AL832877 xref: EMBL:AY257864 xref: EMBL:AY257865 xref: EMBL:AY257866 xref: EMBL:BC068082 xref: EMBL:CR749498 xref: HGNC:HGNC:7907 xref: UniGene:Hs.511991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057162 ! NPHP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018837 name: NPHP4_human def: "Nephrocystin-4 gene" [UniProtKB:O75161] synonym: "KIAA0673" EXACT [UniProtKB:O75161] xref: EMBL:AB014573 xref: EMBL:AF537130 xref: EMBL:AY118228 xref: HGNC:HGNC:19104 xref: UniGene:Hs.462348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054609 ! NPHP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018838 name: NPSR1_human def: "Neuropeptide S receptor gene" [UniProtKB:Q6W5P4] synonym: "GPR154" EXACT [UniProtKB:Q6W5P4] synonym: "GPRA" EXACT [UniProtKB:Q6W5P4] synonym: "PGR14" EXACT [UniProtKB:Q6W5P4] xref: EMBL:AK172847 xref: EMBL:AY310326 xref: EMBL:AY310327 xref: EMBL:AY310328 xref: EMBL:AY310329 xref: EMBL:AY310330 xref: EMBL:AY310331 xref: EMBL:AY310332 xref: EMBL:AY956446 xref: EMBL:AY956447 xref: EMBL:AY956448 xref: EMBL:DQ272236 xref: HGNC:HGNC:23631 xref: UniGene:Hs.652373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056968 ! NPSR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018839 name: NPS_human def: "Neuropeptide S precursor gene" [UniProtKB:P0C0P6] xref: EMBL:BD168686 xref: HGNC:HGNC:33940 xref: UniGene:Hs.643423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054954 ! NPS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018840 name: NPTN_human def: "Neuroplastin precursor gene" [UniProtKB:Q9Y639] synonym: "SDFR1" EXACT [UniProtKB:Q9Y639] synonym: "SDR1" EXACT [UniProtKB:Q9Y639] xref: EMBL:AB209812 xref: EMBL:AF109126 xref: EMBL:AF109127 xref: EMBL:BC105979 xref: EMBL:BC117462 xref: HGNC:HGNC:17867 xref: UniGene:Hs.187866 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023179 ! NPTN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018841 name: NPW_human def: "Neuropeptide W precursor gene" [UniProtKB:Q8N729] synonym: "PPL8" EXACT [UniProtKB:Q8N729] synonym: "PPNPW" EXACT [UniProtKB:Q8N729] xref: EMBL:AB084276 xref: HGNC:HGNC:30509 xref: UniGene:Hs.233533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057497 ! NPW_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018842 name: NPY1R_human def: "Neuropeptide Y receptor type 1 gene" [UniProtKB:P25929] synonym: "NPYR" EXACT [UniProtKB:P25929] synonym: "NPYY1" EXACT [UniProtKB:P25929] xref: EMBL:AY548168 xref: EMBL:BC036657 xref: EMBL:BC071720 xref: EMBL:L07614 xref: EMBL:L07615 xref: EMBL:M84755 xref: EMBL:M88461 xref: HGNC:HGNC:7956 xref: UniGene:Hs.519057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055187 ! NPY1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018843 name: NPY2R_human def: "Neuropeptide Y receptor type 2 gene" [UniProtKB:P49146] xref: EMBL:AY236540 xref: EMBL:BC075052 xref: EMBL:BC075053 xref: EMBL:U32500 xref: EMBL:U36269 xref: EMBL:U42389 xref: EMBL:U42766 xref: EMBL:U50146 xref: EMBL:U76254 xref: HGNC:HGNC:7957 xref: UniGene:Hs.37125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055418 ! NPY2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018844 name: PPYR1_human def: "Neuropeptide Y receptor type 4 gene" [UniProtKB:P50391] synonym: "NPY4R" EXACT [UniProtKB:P50391] xref: EMBL:AY268432 xref: EMBL:AY649985 xref: EMBL:BC096238 xref: EMBL:U35232 xref: EMBL:U42387 xref: EMBL:Z66526 xref: HGNC:HGNC:9329 xref: UniGene:Hs.524719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055447 ! NPY4R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018845 name: NPY5R_human def: "Neuropeptide Y receptor type 5 gene" [UniProtKB:Q15761] synonym: "NPYR5" EXACT [UniProtKB:Q15761] xref: EMBL:AL135818 xref: EMBL:AY322538 xref: EMBL:BC042416 xref: EMBL:CH471056 xref: EMBL:U56079 xref: EMBL:U66275 xref: EMBL:U94320 xref: HGNC:HGNC:7958 xref: UniGene:Hs.519058 xref: UniGene:Hs.598503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056105 ! NPY5R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018846 name: NPY_human def: "Neuropeptide Y precursor gene" [UniProtKB:P01303] xref: EMBL:AC004485 xref: EMBL:BC029497 xref: EMBL:K01911 xref: EMBL:M14296 xref: EMBL:M14297 xref: EMBL:M14298 xref: EMBL:M15789 xref: HGNC:HGNC:7955 xref: UniGene:Hs.1832 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054851 ! NPY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018847 name: NR0B1_human def: "Nuclear receptor subfamily 0 group B member 1 gene" [UniProtKB:P51843] synonym: "AHC" EXACT [UniProtKB:P51843] synonym: "DAX1" EXACT [UniProtKB:P51843] xref: EMBL:AC005185 xref: EMBL:BC011564 xref: EMBL:S74720 xref: EMBL:U31929 xref: HGNC:HGNC:7960 xref: UniGene:Hs.268490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053918 ! A6NNU8_HUMAN relationship: codes_for CCO:B0055483 ! NR0B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018848 name: NR0B2_human def: "Nuclear receptor subfamily 0 group B member 2 gene" [UniProtKB:Q15466] synonym: "SHP" EXACT [UniProtKB:Q15466] xref: EMBL:AB058644 xref: EMBL:AL356390 xref: EMBL:BC030207 xref: EMBL:L76571 xref: HGNC:HGNC:7961 xref: UniGene:Hs.427055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056067 ! NR0B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018849 name: NR1D1_human def: "Nuclear receptor subfamily 1 group D member 1 gene" [UniProtKB:P20393] synonym: "EAR1" EXACT [UniProtKB:P20393] synonym: "HREV" EXACT [UniProtKB:P20393] synonym: "THRAL" EXACT [UniProtKB:P20393] xref: EMBL:BC047875 xref: EMBL:BC056148 xref: EMBL:M24898 xref: EMBL:M24900 xref: EMBL:M34339 xref: EMBL:M34340 xref: EMBL:X55066 xref: EMBL:X55067 xref: EMBL:X72631 xref: HGNC:HGNC:7962 xref: UniGene:Hs.592130 xref: UniGene:Hs.724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055121 ! NR1D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018850 name: NR1D2_human def: "Nuclear receptor subfamily 1 group D member 2 gene" [UniProtKB:Q14995] xref: EMBL:AC124914 xref: EMBL:BC045613 xref: EMBL:BC070035 xref: EMBL:CR457434 xref: EMBL:D16815 xref: EMBL:L31785 xref: HGNC:HGNC:7963 xref: UniGene:Hs.37288 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056031 ! NR1D2_HUMAN relationship: codes_for CCO:B0056755 ! Q6I9S1_HUMAN relationship: codes_for CCO:B0056852 ! Q6NSM0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018851 name: NR1H2_human def: "Oxysterols receptor LXR-beta gene" [UniProtKB:P55055] synonym: "LXRB" EXACT [UniProtKB:P55055] synonym: "NER" EXACT [UniProtKB:P55055] synonym: "UNR" EXACT [UniProtKB:P55055] xref: EMBL:BC007790 xref: EMBL:BC033500 xref: EMBL:BC047750 xref: EMBL:BC074500 xref: EMBL:U07132 xref: EMBL:U14534 xref: HGNC:HGNC:7965 xref: UniGene:Hs.432976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055525 ! NR1H2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018852 name: NR1H3_human def: "Oxysterols receptor LXR-alpha gene" [UniProtKB:Q13133] synonym: "LXRA" EXACT [UniProtKB:Q13133] xref: EMBL:BC008819 xref: EMBL:BC041172 xref: EMBL:CH471064 xref: EMBL:U22662 xref: HGNC:HGNC:7966 xref: UniGene:Hs.438863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055878 ! NR1H3_HUMAN relationship: codes_for CCO:B0057352 ! Q8IW13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018853 name: NR1H4_human def: "Bile acid receptor gene" [UniProtKB:Q96RI1] synonym: "BAR" EXACT [UniProtKB:Q96RI1] synonym: "FXR" EXACT [UniProtKB:Q96RI1] synonym: "HRR1" EXACT [UniProtKB:Q96RI1] synonym: "RIP14" EXACT [UniProtKB:Q96RI1] xref: EMBL:AF384555 xref: EMBL:AF478445 xref: EMBL:AF478446 xref: EMBL:U68233 xref: HGNC:HGNC:7967 xref: UniGene:Hs.282735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058376 ! NR1H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018854 name: NR1I2_human def: "Nuclear receptor subfamily 1 group I member 2 gene" [UniProtKB:O75469] synonym: "PXR" EXACT [UniProtKB:O75469] xref: EMBL:AF061056 xref: EMBL:AF084644 xref: EMBL:AF084645 xref: EMBL:AF364606 xref: EMBL:AJ009936 xref: EMBL:AJ009937 xref: EMBL:AY091855 xref: EMBL:BC017304 xref: EMBL:DQ911122 xref: EMBL:DQ923326 xref: EMBL:EF614253 xref: HGNC:HGNC:7968 xref: UniGene:Hs.7303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054639 ! NR1I2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018855 name: NR1I3_human def: "Nuclear receptor subfamily 1 group I member 3 gene" [UniProtKB:Q14994] synonym: "CAR" EXACT [UniProtKB:Q14994] xref: EMBL:AY572806 xref: EMBL:AY572808 xref: EMBL:AY572809 xref: EMBL:AY572810 xref: EMBL:AY572811 xref: EMBL:AY572812 xref: EMBL:AY572813 xref: EMBL:AY572814 xref: EMBL:AY572815 xref: EMBL:AY572816 xref: EMBL:AY572817 xref: EMBL:AY572818 xref: EMBL:AY572819 xref: EMBL:AY572820 xref: EMBL:AY572822 xref: EMBL:AY572823 xref: EMBL:AY572826 xref: EMBL:AY572827 xref: EMBL:BC069626 xref: EMBL:BC069651 xref: EMBL:BC121120 xref: EMBL:BC121121 xref: EMBL:CH471121 xref: EMBL:Z30425 xref: HGNC:HGNC:7969 xref: UniGene:Hs.349642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055820 ! Q0VAC9_HUMAN relationship: codes_for CCO:B0056030 ! NR1I3_HUMAN relationship: codes_for CCO:B0056737 ! Q6GZ68_HUMAN relationship: codes_for CCO:B0056738 ! Q6GZ69_HUMAN relationship: codes_for CCO:B0056739 ! Q6GZ72_HUMAN relationship: codes_for CCO:B0056740 ! Q6GZ75_HUMAN relationship: codes_for CCO:B0056741 ! Q6GZ76_HUMAN relationship: codes_for CCO:B0056742 ! Q6GZ77_HUMAN relationship: codes_for CCO:B0056743 ! Q6GZ78_HUMAN relationship: codes_for CCO:B0056744 ! Q6GZ79_HUMAN relationship: codes_for CCO:B0056745 ! Q6GZ81_HUMAN relationship: codes_for CCO:B0056746 ! Q6GZ82_HUMAN relationship: codes_for CCO:B0056747 ! Q6GZ83_HUMAN relationship: codes_for CCO:B0056748 ! Q6GZ84_HUMAN relationship: codes_for CCO:B0056749 ! Q6GZ85_HUMAN relationship: codes_for CCO:B0056750 ! Q6GZ87_HUMAN relationship: codes_for CCO:B0056751 ! Q6GZ89_HUMAN relationship: codes_for CCO:B0056854 ! Q6NSZ5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018856 name: NR2C1_human def: "Nuclear receptor subfamily 2 group C member 1 gene" [UniProtKB:P13056] synonym: "TR2" EXACT [UniProtKB:P13056] xref: EMBL:BC040141 xref: EMBL:CH471054 xref: EMBL:M21985 xref: EMBL:M29959 xref: HGNC:HGNC:7971 xref: UniGene:Hs.108301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055009 ! NR2C1_HUMAN relationship: codes_for CCO:B0056084 ! Q15626_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018857 name: NR2C2_human def: "Nuclear receptor subfamily 2 group C member 2 gene" [UniProtKB:P49116] synonym: "TAK1" EXACT [UniProtKB:P49116] synonym: "TR4" EXACT [UniProtKB:P49116] xref: EMBL:BC051670 xref: EMBL:L27586 xref: EMBL:U10990 xref: HGNC:HGNC:7972 xref: UniGene:Hs.591667 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055416 ! NR2C2_HUMAN relationship: codes_for CCO:B0056907 ! Q6PHZ7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018858 name: NR2E1_human def: "Nuclear receptor subfamily 2 group E member 1 gene" [UniProtKB:Q9Y466] synonym: "TLX" EXACT [UniProtKB:Q9Y466] xref: EMBL:AF220532 xref: EMBL:AF411525 xref: EMBL:AK131541 xref: EMBL:AL078596 xref: EMBL:BC028031 xref: EMBL:CH471051 xref: EMBL:Y13276 xref: HGNC:HGNC:7973 xref: UniGene:Hs.157688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056988 ! Q6ZMP8_HUMAN relationship: codes_for CCO:B0059350 ! NR2E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018859 name: NR2E3_human def: "Photoreceptor-specific nuclear receptor gene" [UniProtKB:Q9Y5X4] synonym: "PNR" EXACT [UniProtKB:Q9Y5X4] synonym: "RNR" EXACT [UniProtKB:Q9Y5X4] xref: EMBL:AF121129 xref: EMBL:AF148128 xref: EMBL:AJ276674 xref: HGNC:HGNC:7974 xref: UniGene:Hs.187354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059391 ! NR2E3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018860 name: NR4A1_human def: "Nuclear receptor subfamily 4 group A member 1 gene" [UniProtKB:P22736] synonym: "GFRP1" EXACT [UniProtKB:P22736] synonym: "HMR" EXACT [UniProtKB:P22736] synonym: "NAK1" EXACT [UniProtKB:P22736] xref: EMBL:AK314437 xref: EMBL:BC016147 xref: EMBL:CH471111 xref: EMBL:D49728 xref: EMBL:D85245 xref: EMBL:L13740 xref: HGNC:HGNC:7980 xref: UniGene:Hs.524430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055150 ! NR4A1_HUMAN relationship: codes_for CCO:B0056085 ! Q15627_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018861 name: NR4A2_human def: "Nuclear receptor subfamily 4 group A member 2 gene" [UniProtKB:P43354] synonym: "NOT" EXACT [UniProtKB:P43354] synonym: "NURR1" EXACT [UniProtKB:P43354] synonym: "TINUR" EXACT [UniProtKB:P43354] xref: EMBL:AB017586 xref: EMBL:AB019433 xref: EMBL:AK291456 xref: EMBL:BC009288 xref: EMBL:BC066890 xref: EMBL:S77154 xref: EMBL:X75918 xref: HGNC:HGNC:7981 xref: UniGene:Hs.563344 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055363 ! NR4A2_HUMAN relationship: codes_for CCO:B0056870 ! Q6NXU0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018862 name: NR4A3_human def: "Nuclear receptor subfamily 4 group A member 3 gene" [UniProtKB:Q92570] synonym: "CHN" EXACT [UniProtKB:Q92570] synonym: "CSMF" EXACT [UniProtKB:Q92570] synonym: "MINOR" EXACT [UniProtKB:Q92570] synonym: "NOR1" EXACT [UniProtKB:Q92570] synonym: "TEC" EXACT [UniProtKB:Q92570] xref: EMBL:AL358937 xref: EMBL:AL359710 xref: EMBL:CH471105 xref: EMBL:D78579 xref: EMBL:D85241 xref: EMBL:D85242 xref: EMBL:S81243 xref: EMBL:U12767 xref: EMBL:X89894 xref: HGNC:HGNC:7982 xref: UniGene:Hs.279522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053717 ! A2A3I7_HUMAN relationship: codes_for CCO:B0058065 ! NR4A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018863 name: NR5A2_human def: "Nuclear receptor subfamily 5 group A member 2 gene" [UniProtKB:O00482] synonym: "B1F" EXACT [UniProtKB:O00482] synonym: "CPF" EXACT [UniProtKB:O00482] synonym: "FTF" EXACT [UniProtKB:O00482] xref: EMBL:AF124247 xref: EMBL:AF146343 xref: EMBL:AF190464 xref: EMBL:U80251 xref: EMBL:U93553 xref: HGNC:HGNC:7984 xref: UniGene:Hs.33446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054325 ! NR5A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018864 name: NRBF2_human def: "Nuclear receptor-binding factor 2 gene" [UniProtKB:Q96F24] synonym: "COPR" EXACT [UniProtKB:Q96F24] xref: EMBL:AF267866 xref: EMBL:AK054957 xref: EMBL:AL136656 xref: EMBL:AY267839 xref: EMBL:AY267840 xref: EMBL:BC011707 xref: HGNC:HGNC:19692 xref: UniGene:Hs.449628 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058209 ! NRBF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018865 name: NRD1_human def: "Nardilysin precursor gene" [UniProtKB:O43847] xref: EMBL:AJ000350 xref: EMBL:AL050343 xref: EMBL:AL589663 xref: EMBL:BC008775 xref: EMBL:U64898 xref: EMBL:X93207 xref: EMBL:X93209 xref: HGNC:HGNC:7995 xref: UniGene:Hs.584782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054526 ! NRDC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018866 name: NRF1_human def: "Nuclear respiratory factor 1 gene" [UniProtKB:Q16656] xref: EMBL:L22454 xref: EMBL:U02683 xref: EMBL:U18375 xref: EMBL:U18376 xref: EMBL:U18377 xref: EMBL:U18378 xref: EMBL:U18379 xref: EMBL:U18380 xref: EMBL:U18381 xref: EMBL:U18382 xref: EMBL:U18383 xref: HGNC:HGNC:7996 xref: UniGene:Hs.654363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056169 ! NRF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018867 name: NRG2_human def: "Pro-neuregulin-2, membrane-bound isoform precursor gene" [UniProtKB:O14511] synonym: "NTAK" EXACT [UniProtKB:O14511] xref: EMBL:AB005060 xref: EMBL:AF119151 xref: EMBL:AF119152 xref: EMBL:AF119153 xref: EMBL:AF119154 xref: EMBL:AF119155 xref: EMBL:AF119156 xref: EMBL:AF119157 xref: EMBL:AF119158 xref: EMBL:AF119159 xref: EMBL:AF119160 xref: EMBL:AF119161 xref: EMBL:AF119162 xref: HGNC:HGNC:7998 xref: UniGene:Hs.408515 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054346 ! NRG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018868 name: NRG3_human def: "Pro-neuregulin-3, membrane-bound isoform precursor gene" [UniProtKB:P56975] xref: EMBL:AL096706 xref: EMBL:AL136085 xref: EMBL:AL354749 xref: EMBL:AL391478 xref: EMBL:AL513204 xref: EMBL:AL589782 xref: EMBL:DQ001411 xref: EMBL:DQ857894 xref: HGNC:HGNC:7999 xref: UniGene:Hs.125119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055554 ! NRG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018869 name: NRIP1_human def: "Nuclear receptor-interacting protein 1 gene" [UniProtKB:P48552] xref: EMBL:AF127577 xref: EMBL:AF248484 xref: EMBL:AL163207 xref: EMBL:BC040361 xref: EMBL:X84373 xref: HGNC:HGNC:8001 xref: UniGene:Hs.155017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055407 ! NRIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018870 name: NRL_human def: "Neural retina-specific leucine zipper protein gene" [UniProtKB:P54845] xref: EMBL:AL136295 xref: EMBL:BC012395 xref: EMBL:M81840 xref: EMBL:M95925 xref: EMBL:U95012 xref: HGNC:HGNC:8002 xref: UniGene:Hs.652297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054087 ! A8MX14_HUMAN relationship: codes_for CCO:B0055518 ! NRL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018871 name: NRTN_human def: "Neurturin precursor gene" [UniProtKB:Q99748] xref: EMBL:AL161995 xref: EMBL:U78110 xref: HGNC:HGNC:8007 xref: UniGene:Hs.234775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058453 ! NRTN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018872 name: NSBP1_human def: "Nucleosome-binding protein 1 gene" [UniProtKB:P82970] xref: EMBL:AF250329 xref: EMBL:AF250330 xref: EMBL:AK094058 xref: EMBL:BC005342 xref: HGNC:HGNC:8013 xref: UniGene:Hs.282204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055657 ! NSBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018873 name: NSD1_human def: "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific gene" [UniProtKB:Q96L73] synonym: "ARA267" EXACT [UniProtKB:Q96L73] synonym: "KMT3B" EXACT [UniProtKB:Q96L73] xref: EMBL:AF322907 xref: EMBL:AF380302 xref: EMBL:AF395588 xref: EMBL:AY049721 xref: HGNC:HGNC:14234 xref: UniGene:Hs.654666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058266 ! NSD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018874 name: WHSC1_human def: "Probable histone-lysine N-methyltransferase NSD2 gene" [UniProtKB:O96028] synonym: "KIAA1090" EXACT [UniProtKB:O96028] synonym: "MMSET" EXACT [UniProtKB:O96028] synonym: "NSD2" EXACT [UniProtKB:O96028] synonym: "TRX5" EXACT [UniProtKB:O96028] xref: EMBL:AB029013 xref: EMBL:AF071593 xref: EMBL:AF071594 xref: EMBL:AF083386 xref: EMBL:AF083387 xref: EMBL:AF083388 xref: EMBL:AF083389 xref: EMBL:AF083390 xref: EMBL:AF083391 xref: EMBL:AF178198 xref: EMBL:AF178199 xref: EMBL:AF178200 xref: EMBL:AF178201 xref: EMBL:AF178202 xref: EMBL:AF178203 xref: EMBL:AF178204 xref: EMBL:AF178205 xref: EMBL:AF178206 xref: EMBL:AF178207 xref: EMBL:AF178208 xref: EMBL:AF178209 xref: EMBL:AF178210 xref: EMBL:AF178211 xref: EMBL:AF178212 xref: EMBL:AF178213 xref: EMBL:AF178214 xref: EMBL:AF178215 xref: EMBL:AF178216 xref: EMBL:AF178217 xref: EMBL:AF178218 xref: EMBL:AF178219 xref: EMBL:AF330040 xref: EMBL:AJ007042 xref: EMBL:AY694128 xref: EMBL:BC052254 xref: EMBL:BC070176 xref: EMBL:BC094825 xref: HGNC:HGNC:12766 xref: UniGene:Hs.113876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054823 ! NSD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018875 name: WHSC1L1_human def: "Histone-lysine N-methyltransferase NSD3 gene" [UniProtKB:Q9BZ95] synonym: "DC28" EXACT [UniProtKB:Q9BZ95] synonym: "NSD3" EXACT [UniProtKB:Q9BZ95] xref: EMBL:AF255649 xref: EMBL:AF332468 xref: EMBL:AF332469 xref: EMBL:AJ295990 xref: EMBL:AJ295991 xref: EMBL:AJ295992 xref: EMBL:AK000360 xref: EMBL:AK022560 xref: EMBL:AK127594 xref: EMBL:BC012059 xref: EMBL:BC062631 xref: EMBL:BC101717 xref: EMBL:BC107734 xref: EMBL:BC113469 xref: EMBL:BC115006 xref: HGNC:HGNC:12767 xref: UniGene:Hs.700599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058592 ! NSD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018876 name: NSG1_human def: "Neuron-specific protein family member 1 gene" [UniProtKB:P42857] synonym: "D4S234" EXACT [UniProtKB:P42857] xref: EMBL:BC001745 xref: EMBL:BC034227 xref: EMBL:M98528 xref: EMBL:M98529 xref: UniGene:Hs.518595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055356 ! NSG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018877 name: NSG2_human def: "Neuron-specific protein family member 2 gene" [UniProtKB:Q9Y328] xref: EMBL:AF113537 xref: EMBL:AF133422 xref: EMBL:BC002619 xref: UniGene:Hs.559412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059328 ! NSG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018878 name: SMPD2_human def: "Sphingomyelin phosphodiesterase 2 gene" [UniProtKB:O60906] xref: EMBL:AJ222801 xref: EMBL:AL109947 xref: EMBL:BC000038 xref: HGNC:HGNC:11121 xref: UniGene:Hs.55235 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054589 ! NSMA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018879 name: NT5M_human def: "5'(3')-deoxyribonucleotidase, mitochondrial precursor gene" [UniProtKB:Q9NPB1] synonym: "DNT2" EXACT [UniProtKB:Q9NPB1] xref: EMBL:AF210652 xref: EMBL:AJ277557 xref: EMBL:BC035838 xref: HGNC:HGNC:15769 xref: UniGene:Hs.513977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058844 ! NT5M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018880 name: LAT2_human def: "Linker for activation of T-cells family member 2 gene" [UniProtKB:Q9GZY6] synonym: "HSPC046" EXACT [UniProtKB:Q9GZY6] synonym: "LAB" EXACT [UniProtKB:Q9GZY6] synonym: "NTAL" EXACT [UniProtKB:Q9GZY6] synonym: "WBS15" EXACT [UniProtKB:Q9GZY6] synonym: "WBSCR15" EXACT [UniProtKB:Q9GZY6] synonym: "WBSCR5" EXACT [UniProtKB:Q9GZY6] xref: EMBL:AC005081 xref: EMBL:AF045555 xref: EMBL:AF161531 xref: EMBL:AF252611 xref: EMBL:AF252612 xref: EMBL:AF252613 xref: EMBL:AF252614 xref: EMBL:AF257135 xref: EMBL:AK002099 xref: EMBL:AK092904 xref: EMBL:AK290916 xref: EMBL:AY190023 xref: EMBL:BC001609 xref: EMBL:BC006080 xref: EMBL:BC009204 xref: EMBL:CH471200 xref: HGNC:HGNC:12749 xref: UniGene:Hs.647049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058644 ! NTAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018881 name: NTF3_human def: "Neurotrophin-3 precursor gene" [UniProtKB:P20783] xref: EMBL:BC069773 xref: EMBL:BC107075 xref: EMBL:CH471116 xref: EMBL:CR541906 xref: EMBL:M37763 xref: EMBL:M61180 xref: EMBL:X53655 xref: HGNC:HGNC:8023 xref: UniGene:Hs.99171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055124 ! NTF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018882 name: NTF4_human def: "Neurotrophin-4 precursor gene" [UniProtKB:P34130] synonym: "NTF5" EXACT [UniProtKB:P34130] xref: EMBL:BC012421 xref: EMBL:BT019368 xref: EMBL:BT019369 xref: EMBL:CR541900 xref: EMBL:M86528 xref: HGNC:HGNC:8024 xref: UniGene:Hs.266902 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055270 ! NTF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018883 name: NTSR1_human def: "Neurotensin receptor type 1 gene" [UniProtKB:P30989] synonym: "NTRR" EXACT [UniProtKB:P30989] xref: EMBL:AL035669 xref: EMBL:AL357033 xref: EMBL:AY429106 xref: EMBL:X70070 xref: HGNC:HGNC:8039 xref: UniGene:Hs.590869 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055231 ! NTR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018884 name: NTSR2_human def: "Neurotensin receptor type 2 gene" [UniProtKB:O95665] xref: EMBL:AC110754 xref: EMBL:AY429107 xref: EMBL:BC022501 xref: EMBL:BC037776 xref: EMBL:CH471053 xref: EMBL:Y10148 xref: HGNC:HGNC:8040 xref: UniGene:Hs.131138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054780 ! NTR2_HUMAN relationship: codes_for CCO:B0056374 ! Q57Z87_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018885 name: NTRK1_human def: "High affinity nerve growth factor receptor precursor gene" [UniProtKB:P04629] synonym: "TRK" EXACT [UniProtKB:P04629] xref: EMBL:AB019488 xref: EMBL:AL158169 xref: EMBL:AY321513 xref: EMBL:BC062580 xref: EMBL:M23102 xref: EMBL:X03541 xref: EMBL:X06704 xref: EMBL:X62947 xref: EMBL:X85960 xref: HGNC:HGNC:8031 xref: UniGene:Hs.406293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053813 ! A6NF12_HUMAN relationship: codes_for CCO:B0054098 ! A8MXI6_HUMAN relationship: codes_for CCO:B0054892 ! NTRK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018886 name: NTRK2_human def: "BDNF/NT-3 growth factors receptor precursor gene" [UniProtKB:Q16620] synonym: "TRKB" EXACT [UniProtKB:Q16620] xref: EMBL:AF410899 xref: EMBL:AF410900 xref: EMBL:AF508964 xref: EMBL:AL390777 xref: EMBL:AL445532 xref: EMBL:AL596132 xref: EMBL:BC031835 xref: EMBL:CH471089 xref: EMBL:S76473 xref: EMBL:S76474 xref: EMBL:U12140 xref: EMBL:X75958 xref: HGNC:HGNC:8032 xref: UniGene:Hs.494312 xref: UniGene:Hs.653428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056161 ! NTRK2_HUMAN relationship: codes_for CCO:B0058025 ! Q8WXJ7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018887 name: NTRK3_human def: "NT-3 growth factor receptor precursor gene" [UniProtKB:Q16288] synonym: "TRKC" EXACT [UniProtKB:Q16288] xref: EMBL:AJ224521 xref: EMBL:AJ224522 xref: EMBL:AJ224523 xref: EMBL:AJ224524 xref: EMBL:AJ224525 xref: EMBL:AJ224526 xref: EMBL:AJ224527 xref: EMBL:AJ224528 xref: EMBL:AJ224529 xref: EMBL:AJ224530 xref: EMBL:AJ224531 xref: EMBL:AJ224532 xref: EMBL:AJ224533 xref: EMBL:AJ224534 xref: EMBL:AJ224535 xref: EMBL:S76475 xref: EMBL:S76476 xref: EMBL:U05012 xref: HGNC:HGNC:8033 xref: UniGene:Hs.410969 xref: UniGene:Hs.706364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056133 ! NTRK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018888 name: NUFIP1_human def: "Nuclear fragile X mental retardation-interacting protein 1 gene" [UniProtKB:Q9UHK0] xref: EMBL:AF159548 xref: EMBL:AL354816 xref: EMBL:AL359706 xref: EMBL:BC017745 xref: HGNC:HGNC:8057 xref: UniGene:Hs.525006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059143 ! NUFP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018889 name: NUMBL_human def: "Numb-like protein gene" [UniProtKB:Q9Y6R0] xref: EMBL:AF015041 xref: EMBL:BC001794 xref: EMBL:BT009807 xref: HGNC:HGNC:8061 xref: UniGene:Hs.326953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059414 ! NUMBL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018890 name: NUP98_human def: "Nuclear pore complex protein Nup98-Nup96 precursor gene" [UniProtKB:P52948] synonym: "ADAR2" EXACT [UniProtKB:P52948] xref: EMBL:AB040538 xref: EMBL:AF071076 xref: EMBL:AF071077 xref: EMBL:AF116074 xref: EMBL:AF231130 xref: EMBL:AL133601 xref: EMBL:AL137613 xref: EMBL:BC012906 xref: EMBL:BC041136 xref: EMBL:BT007349 xref: EMBL:U41815 xref: HGNC:HGNC:8068 xref: UniGene:Hs.524750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055505 ! NUP98_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018891 name: HRB_human def: "Nucleoporin-like protein RIP gene" [UniProtKB:P52594] synonym: "RAB" EXACT [UniProtKB:P52594] synonym: "RIP" EXACT [UniProtKB:P52594] xref: EMBL:AC097662 xref: EMBL:AC105286 xref: EMBL:BC030592 xref: EMBL:BC096272 xref: EMBL:BC096273 xref: EMBL:BC096274 xref: EMBL:BC096275 xref: EMBL:L42025 xref: EMBL:X89478 xref: HGNC:HGNC:5175 xref: UniGene:Hs.591619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055487 ! NUPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018892 name: NUPR1_human def: "Nuclear protein 1 gene" [UniProtKB:O60356] synonym: "COM1" EXACT [UniProtKB:O60356] xref: EMBL:AC002425 xref: EMBL:AF069073 xref: EMBL:AF069074 xref: EMBL:AF135266 xref: EMBL:BC002434 xref: EMBL:BT006896 xref: UniGene:Hs.513463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054550 ! NUPR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018893 name: NXN_human def: "Nucleoredoxin gene" [UniProtKB:Q6DKJ4] synonym: "NRX" EXACT [UniProtKB:Q6DKJ4] xref: EMBL:AC015884 xref: EMBL:AC036164 xref: EMBL:AC087392 xref: EMBL:AK022676 xref: EMBL:AK027451 xref: EMBL:BC063828 xref: EMBL:BC073845 xref: EMBL:BC104634 xref: HGNC:HGNC:18008 xref: UniGene:Hs.527989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056725 ! NXN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018894 name: NXPH2_human def: "Neurexophilin-2 precursor gene" [UniProtKB:O95156] synonym: "NPH2" EXACT [UniProtKB:O95156] xref: EMBL:AB162675 xref: EMBL:AF043467 xref: EMBL:BC101462 xref: EMBL:BC101463 xref: EMBL:BC104741 xref: HGNC:HGNC:8076 xref: UniGene:Hs.435019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054728 ! NXPH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018895 name: NXPH3_human def: "Neurexophilin-3 precursor gene" [UniProtKB:O95157] synonym: "KIAA1159" EXACT [UniProtKB:O95157] synonym: "NPH3" EXACT [UniProtKB:O95157] synonym: "UNQ687/PRO1327" EXACT [UniProtKB:O95157] xref: EMBL:AB032985 xref: EMBL:AF043468 xref: EMBL:AY358526 xref: EMBL:BC022541 xref: HGNC:HGNC:8077 xref: UniGene:Hs.55069 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054729 ! NXPH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018896 name: NXPH4_human def: "Neurexophilin-4 precursor gene" [UniProtKB:O95158] synonym: "NPH4" EXACT [UniProtKB:O95158] synonym: "UNQ1928/PRO4403" EXACT [UniProtKB:O95158] xref: EMBL:AF043469 xref: EMBL:AY358614 xref: EMBL:BC036679 xref: EMBL:BC053581 xref: HGNC:HGNC:8078 xref: UniGene:Hs.534396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054730 ! NXPH4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018897 name: OR10A2_human def: "Olfactory receptor 10A2 gene" [UniProtKB:Q9H208] synonym: "OR10A2P" EXACT [UniProtKB:Q9H208] xref: EMBL:AC017103 xref: EMBL:AF321237 xref: EMBL:AF399624 xref: EMBL:BK004293 xref: HGNC:HGNC:8161 xref: UniGene:Hs.371762 xref: UniGene:Hs.447478 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058670 ! O10A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018898 name: OR10A3_human def: "Olfactory receptor 10A3 gene" [UniProtKB:P58181] xref: EMBL:AB065768 xref: EMBL:AC044810 xref: EMBL:AF399634 xref: EMBL:BK004404 xref: EMBL:X64986 xref: HGNC:HGNC:8162 xref: UniGene:Hs.381322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055567 ! O10A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018899 name: OR10A4_human def: "Olfactory receptor 10A4 gene" [UniProtKB:Q9H209] synonym: "OR10A4P" EXACT [UniProtKB:Q9H209] xref: EMBL:AF209506 xref: EMBL:AF321237 xref: EMBL:AF399625 xref: HGNC:HGNC:15130 xref: UniGene:Hs.448685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058671 ! O10A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018900 name: OR10A5_human def: "Olfactory receptor 10A5 gene" [UniProtKB:Q9H207] synonym: "OR10A1" EXACT [UniProtKB:Q9H207] xref: EMBL:AF065874 xref: EMBL:AF321237 xref: EMBL:AF324499 xref: EMBL:AF399623 xref: EMBL:BC093651 xref: EMBL:BC093653 xref: EMBL:BK004296 xref: EMBL:CH471064 xref: HGNC:HGNC:15131 xref: UniGene:Hs.447478 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056792 ! Q6IFG6_HUMAN relationship: codes_for CCO:B0058669 ! O10A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018901 name: OR10A6_human def: "Olfactory receptor 10A6 gene" [UniProtKB:Q8NH74] xref: EMBL:AB065515 xref: EMBL:BK004403 xref: HGNC:HGNC:15132 xref: UniGene:Hs.528593 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057845 ! O10A6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018902 name: OR10A7_human def: "Olfactory receptor 10A7 gene" [UniProtKB:Q8NGE5] xref: EMBL:AB065864 xref: EMBL:AF399626 xref: EMBL:BK004327 xref: HGNC:HGNC:15329 xref: UniGene:Hs.554557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057661 ! O10A7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018903 name: OR10AD1_human def: "Olfactory receptor 10AD1 gene" [UniProtKB:Q8NGE0] synonym: "OR10AD1P" EXACT [UniProtKB:Q8NGE0] xref: EMBL:AB065872 xref: EMBL:BK004354 xref: HGNC:HGNC:14819 xref: UniGene:Hs.446790 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057658 ! O10AD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018904 name: OR10AG1_human def: "Olfactory receptor 10AG1 gene" [UniProtKB:Q8NH19] xref: EMBL:AB065594 xref: EMBL:BK004519 xref: HGNC:HGNC:19607 xref: UniGene:Hs.554525 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057810 ! O10AG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018905 name: OR10C1_human def: "Olfactory receptor 10C1 gene" [UniProtKB:Q96KK4] synonym: "OR10C2" EXACT [UniProtKB:Q96KK4] xref: EMBL:AF399627 xref: EMBL:AL035542 xref: EMBL:AL645927 xref: EMBL:BX248400 xref: EMBL:CR388393 xref: EMBL:CR759768 xref: HGNC:HGNC:8165 xref: UniGene:Hs.631997 xref: UniGene:Hs.686940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053728 ! A2BF34_HUMAN relationship: codes_for CCO:B0053866 ! A6NJ05_HUMAN relationship: codes_for CCO:B0056542 ! Q5SUN7_HUMAN relationship: codes_for CCO:B0058259 ! O10C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018906 name: OR10D4P_human def: "Putative olfactory receptor 10D4 gene" [UniProtKB:Q8NGN7] synonym: "OR10D4" EXACT [UniProtKB:Q8NGN7] xref: EMBL:AB065753 xref: HGNC:HGNC:14770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057724 ! O10D4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018907 name: OR10G2_human def: "Olfactory receptor 10G2 gene" [UniProtKB:Q8NGC3] xref: EMBL:AB065894 xref: HGNC:HGNC:8170 xref: UniGene:Hs.554580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057646 ! O10G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018908 name: OR10G3_human def: "Olfactory receptor 10G3 gene" [UniProtKB:Q8NGC4] xref: EMBL:AB065893 xref: EMBL:AF399566 xref: EMBL:BK004525 xref: HGNC:HGNC:8171 xref: UniGene:Hs.554581 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057647 ! O10G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018909 name: OR10G4_human def: "Olfactory receptor 10G4 gene" [UniProtKB:Q8NGN3] xref: EMBL:AB065757 xref: EMBL:AP001884 xref: EMBL:BK004502 xref: HGNC:HGNC:14809 xref: UniGene:Hs.553760 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054037 ! A8MU07_HUMAN relationship: codes_for CCO:B0057720 ! O10G4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018910 name: OR10G6_human def: "Olfactory receptor 10G6 gene" [UniProtKB:Q8NH81] synonym: "OR10G6P" EXACT [UniProtKB:Q8NH81] xref: EMBL:AB065508 xref: EMBL:BK004312 xref: HGNC:HGNC:14836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057852 ! O10G6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018911 name: OR10G7_human def: "Olfactory receptor 10G7 gene" [UniProtKB:Q8NGN6] xref: EMBL:AB065754 xref: HGNC:HGNC:14842 xref: UniGene:Hs.553761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057723 ! O10G7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018912 name: OR10G8_human def: "Olfactory receptor 10G8 gene" [UniProtKB:Q8NGN5] xref: EMBL:AB065755 xref: EMBL:AP001884 xref: EMBL:BK004510 xref: HGNC:HGNC:14845 xref: UniGene:Hs.553635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054093 ! A8MX88_HUMAN relationship: codes_for CCO:B0057722 ! O10G8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018913 name: OR10G9_human def: "Olfactory receptor 10G9 gene" [UniProtKB:Q8NGN4] synonym: "OR10G10P" EXACT [UniProtKB:Q8NGN4] xref: EMBL:AB065756 xref: EMBL:AP001884 xref: HGNC:HGNC:15129 xref: UniGene:Hs.553636 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054135 ! A8MZ16_HUMAN relationship: codes_for CCO:B0057721 ! O10G9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018914 name: OR10H1_human def: "Olfactory receptor 10H1 gene" [UniProtKB:Q9Y4A9] xref: EMBL:AC004510 xref: EMBL:AF399584 xref: HGNC:HGNC:8172 xref: UniGene:Hs.533925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059356 ! O10H1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018915 name: OR10H2_human def: "Olfactory receptor 10H2 gene" [UniProtKB:O60403] xref: EMBL:AC004597 xref: EMBL:AF399585 xref: EMBL:BC069085 xref: EMBL:BC069457 xref: EMBL:BC112178 xref: EMBL:BC113647 xref: EMBL:BK004211 xref: HGNC:HGNC:8173 xref: UniGene:Hs.247694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054552 ! O10H2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018916 name: OR10H3_human def: "Olfactory receptor 10H3 gene" [UniProtKB:O60404] xref: EMBL:AC004597 xref: EMBL:BC106707 xref: EMBL:BC113844 xref: HGNC:HGNC:8174 xref: UniGene:Hs.553524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054553 ! O10H3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018917 name: OR10H4_human def: "Olfactory receptor 10H4 gene" [UniProtKB:Q8NGA5] xref: EMBL:AB065921 xref: EMBL:AF399586 xref: HGNC:HGNC:15388 xref: UniGene:Hs.553579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057634 ! O10H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018918 name: OR10H5_human def: "Olfactory receptor 10H5 gene" [UniProtKB:Q8NGA6] xref: EMBL:AB065920 xref: EMBL:AF399583 xref: HGNC:HGNC:15389 xref: UniGene:Hs.553676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057635 ! O10H5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018919 name: OR10J1_human def: "Olfactory receptor 10J1 gene" [UniProtKB:P30954] xref: EMBL:AF399587 xref: EMBL:AL513323 xref: EMBL:BC069150 xref: EMBL:BC112290 xref: EMBL:BK004527 xref: EMBL:X64995 xref: HGNC:HGNC:8175 xref: UniGene:Hs.532661 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053805 ! A6NE96_HUMAN relationship: codes_for CCO:B0055228 ! O10J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018920 name: OR10J3_human def: "Olfactory receptor 10J3 gene" [UniProtKB:Q5JRS4] synonym: "OR10J3P" EXACT [UniProtKB:Q5JRS4] xref: EMBL:AL513323 xref: HGNC:HGNC:14992 xref: UniGene:Hs.553833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056470 ! O10J3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018921 name: OR10J4_human def: "Olfactory receptor 10J4 gene" [UniProtKB:P0C629] synonym: "OR10J4P" EXACT [UniProtKB:P0C629] xref: EMBL:AF399454 xref: EMBL:AL663023 xref: HGNC:HGNC:15408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054959 ! O10J4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018922 name: OR10J5_human def: "Olfactory receptor 10J5 gene" [UniProtKB:Q8NHC4] xref: EMBL:AB065443 xref: HGNC:HGNC:14993 xref: UniGene:Hs.553587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057870 ! O10J5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018923 name: OR10J6P_human def: "Putative olfactory receptor 10J6 gene" [UniProtKB:Q8NGY7] synonym: "OR10J6" EXACT [UniProtKB:Q8NGY7] xref: EMBL:AB065629 xref: EMBL:AF399588 xref: HGNC:HGNC:14994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057787 ! O10J6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018924 name: OR10K1_human def: "Olfactory receptor 10K1 gene" [UniProtKB:Q8NGX5] xref: EMBL:AB065641 xref: HGNC:HGNC:14693 xref: UniGene:Hs.690410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057777 ! O10K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018925 name: OR10K2_human def: "Olfactory receptor 10K2 gene" [UniProtKB:Q6IF99] xref: EMBL:AB065642 xref: EMBL:AL121986 xref: EMBL:BK004363 xref: HGNC:HGNC:14826 xref: UniGene:Hs.626815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056784 ! O10K2_HUMAN relationship: codes_for CCO:B0057776 ! Q8NGX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018926 name: OR10Q1_human def: "Olfactory receptor 10Q1 gene" [UniProtKB:Q8NGQ4] xref: EMBL:AB065735 xref: HGNC:HGNC:15134 xref: UniGene:Hs.553646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057736 ! O10Q1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018927 name: OR10T2_human def: "Olfactory receptor 10T2 gene" [UniProtKB:Q8NGX3] xref: EMBL:AB065643 xref: EMBL:AL121986 xref: EMBL:BK004364 xref: HGNC:HGNC:14816 xref: UniGene:Hs.553588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057775 ! O10T2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018928 name: OR10V1_human def: "Olfactory receptor 10V1 gene" [UniProtKB:Q8NGI7] xref: EMBL:AB065807 xref: EMBL:AF399593 xref: HGNC:HGNC:15136 xref: UniGene:Hs.589001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057684 ! O10V1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018929 name: OR10W1_human def: "Olfactory receptor 10W1 gene" [UniProtKB:Q8NGF6] synonym: "OR10W1P" EXACT [UniProtKB:Q8NGF6] synonym: "UNQ6469/PRO34070" EXACT [UniProtKB:Q8NGF6] xref: EMBL:AB065850 xref: EMBL:AP000435 xref: EMBL:AY358251 xref: EMBL:BK004490 xref: HGNC:HGNC:15139 xref: UniGene:Hs.531507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054024 ! A8MTE1_HUMAN relationship: codes_for CCO:B0057666 ! O10W1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018930 name: OR10X1_human def: "Olfactory receptor 10X1 gene" [UniProtKB:Q8NGY0] synonym: "OR10X1P" EXACT [UniProtKB:Q8NGY0] xref: EMBL:AB065636 xref: EMBL:AL160283 xref: EMBL:BK004194 xref: HGNC:HGNC:14995 xref: UniGene:Hs.553589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057781 ! O10X1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018931 name: OR10Z1_human def: "Olfactory receptor 10Z1 gene" [UniProtKB:Q8NGY1] xref: EMBL:AB065635 xref: EMBL:AL353894 xref: HGNC:HGNC:14996 xref: UniGene:Hs.553590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057782 ! O10Z1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018932 name: OR11A1_human def: "Olfactory receptor 11A1 gene" [UniProtKB:Q9GZK7] synonym: "OR11A2" EXACT [UniProtKB:Q9GZK7] xref: EMBL:AJ302614 xref: EMBL:AJ302615 xref: EMBL:AJ302616 xref: EMBL:AJ302617 xref: EMBL:AJ302618 xref: EMBL:AJ302619 xref: EMBL:AJ302620 xref: EMBL:AJ302621 xref: EMBL:AJ302622 xref: EMBL:AJ302623 xref: EMBL:AJ459857 xref: EMBL:AL035542 xref: EMBL:AL645927 xref: EMBL:AL662869 xref: EMBL:BK004208 xref: EMBL:BX004810 xref: EMBL:BX248400 xref: EMBL:CH471081 xref: HGNC:HGNC:8176 xref: UniGene:Hs.676010 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053727 ! A2BF33_HUMAN relationship: codes_for CCO:B0058627 ! O11A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018933 name: OR11H2_human def: "Olfactory receptor 11H2 gene" [UniProtKB:Q8NH07] synonym: "OR11H2P" EXACT [UniProtKB:Q8NH07] xref: EMBL:AB065607 xref: EMBL:BK004489 xref: HGNC:HGNC:14716 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057803 ! O11H2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018934 name: OR11H4_human def: "Olfactory receptor 11H4 gene" [UniProtKB:Q8NGC9] xref: EMBL:AB065887 xref: EMBL:BK004455 xref: HGNC:HGNC:15347 xref: UniGene:Hs.553767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057651 ! O11H4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018935 name: OR11H6_human def: "Olfactory receptor 11H6 gene" [UniProtKB:Q8NGC7] xref: EMBL:AB065889 xref: EMBL:BK004454 xref: HGNC:HGNC:15349 xref: UniGene:Hs.553575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057649 ! O11H6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018936 name: OR11H7_human def: "Olfactory receptor 11H7 gene" [UniProtKB:Q8NGC8] synonym: "OR11H7P" EXACT [UniProtKB:Q8NGC8] xref: EMBL:AB065888 xref: EMBL:AF399477 xref: EMBL:AL356019 xref: EMBL:BK004619 xref: HGNC:HGNC:15350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057650 ! O11H7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018937 name: OR11L1_human def: "Olfactory receptor 11L1 gene" [UniProtKB:Q8NGX0] xref: EMBL:AB065646 xref: HGNC:HGNC:14998 xref: UniGene:Hs.553781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057772 ! O11L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018938 name: OR12D2_human def: "Olfactory receptor 12D2 gene" [UniProtKB:P58182] xref: EMBL:AC004171 xref: EMBL:AL035542 xref: EMBL:AL645927 xref: EMBL:AL662869 xref: EMBL:BC069123 xref: EMBL:BC101742 xref: EMBL:BC101746 xref: EMBL:BK004523 xref: EMBL:BX005133 xref: EMBL:CR388393 xref: HGNC:HGNC:8178 xref: UniGene:Hs.247862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053725 ! A2BDZ2_HUMAN relationship: codes_for CCO:B0054186 ! B0UY34_HUMAN relationship: codes_for CCO:B0055568 ! O12D2_HUMAN relationship: codes_for CCO:B0056543 ! Q5SUN9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018939 name: OR12D3_human def: "Olfactory receptor 12D3 gene" [UniProtKB:Q9UGF7] xref: EMBL:AJ459858 xref: EMBL:AL096770 xref: EMBL:AL662781 xref: EMBL:AL732432 xref: EMBL:BC069082 xref: EMBL:BC069154 xref: EMBL:BC103892 xref: EMBL:BC106898 xref: EMBL:BK004439 xref: EMBL:BX005133 xref: HGNC:HGNC:13963 xref: UniGene:Hs.272280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059122 ! O12D3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018940 name: OR13C2_human def: "Olfactory receptor 13C2 gene" [UniProtKB:Q8NGS9] xref: EMBL:AB065709 xref: EMBL:AL359846 xref: EMBL:BK004408 xref: HGNC:HGNC:14701 xref: UniGene:Hs.553789 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057751 ! O13C2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018941 name: OR13C4_human def: "Olfactory receptor 13C4 gene" [UniProtKB:Q8NGS5] xref: EMBL:AB065714 xref: EMBL:AF399602 xref: EMBL:AL450426 xref: EMBL:BK004411 xref: HGNC:HGNC:14722 xref: UniGene:Hs.553601 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057748 ! O13C4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018942 name: OR13C5_human def: "Olfactory receptor 13C5 gene" [UniProtKB:Q8NGS8] xref: EMBL:AB065710 xref: EMBL:AL450426 xref: EMBL:BK004409 xref: HGNC:HGNC:15100 xref: UniGene:Hs.553598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057750 ! O13C5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018943 name: OR13C8_human def: "Olfactory receptor 13C8 gene" [UniProtKB:Q8NGS7] xref: EMBL:AB065711 xref: EMBL:AF399599 xref: EMBL:AL450426 xref: HGNC:HGNC:15103 xref: UniGene:Hs.553599 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057749 ! O13C8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018944 name: OR13C9_human def: "Olfactory receptor 13C9 gene" [UniProtKB:Q8NGT0] xref: EMBL:AB065708 xref: HGNC:HGNC:15104 xref: UniGene:Hs.553682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057752 ! O13C9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018945 name: OR13F1_human def: "Olfactory receptor 13F1 gene" [UniProtKB:Q8NGS4] xref: EMBL:AB065715 xref: EMBL:AL450426 xref: EMBL:BK004412 xref: HGNC:HGNC:14723 xref: UniGene:Hs.553602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057747 ! O13F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018946 name: OR13G1_human def: "Olfactory receptor 13G1 gene" [UniProtKB:Q8NGZ3] xref: EMBL:AB065623 xref: EMBL:AL390860 xref: HGNC:HGNC:14999 xref: UniGene:Hs.553834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057791 ! O13G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018947 name: OR13H1_human def: "Olfactory receptor 13H1 gene" [UniProtKB:Q8NG92] xref: EMBL:AB065938 xref: EMBL:AF399633 xref: EMBL:AL049734 xref: EMBL:BK004524 xref: HGNC:HGNC:14755 xref: UniGene:Hs.553711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057625 ! O13H1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018948 name: OR13J1_human def: "Olfactory receptor 13J1 gene" [UniProtKB:Q8NGT2] xref: EMBL:AB065705 xref: EMBL:AF399603 xref: EMBL:AL133410 xref: EMBL:BK004442 xref: HGNC:HGNC:15108 xref: UniGene:Hs.527480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057754 ! O13J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018949 name: OR14A16_human def: "Olfactory receptor 14A16 gene" [UniProtKB:Q8NHC5] synonym: "OR5AT1" EXACT [UniProtKB:Q8NHC5] xref: EMBL:AB065441 xref: EMBL:BK004366 xref: HGNC:HGNC:15022 xref: UniGene:Hs.626620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057871 ! O14AG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018950 name: OR14C36_human def: "Olfactory receptor 14C36 gene" [UniProtKB:Q8NHC7] synonym: "OR5BF1" EXACT [UniProtKB:Q8NHC7] xref: EMBL:AB065439 xref: EMBL:AL450303 xref: EMBL:BK004466 xref: HGNC:HGNC:15026 xref: UniGene:Hs.553583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057873 ! O14CZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018951 name: OR14I1_human def: "Olfactory receptor 14I1 gene" [UniProtKB:A6ND48] synonym: "OR5BU1" EXACT [UniProtKB:A6ND48] synonym: "OR5BU1P" EXACT [UniProtKB:A6ND48] xref: EMBL:AC098483 xref: HGNC:HGNC:19575 xref: UniGene:Hs.449973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053788 ! O14I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018952 name: OR14J1_human def: "Olfactory receptor 14J1 gene" [UniProtKB:Q9UGF5] synonym: "OR5U1" EXACT [UniProtKB:Q9UGF5] xref: EMBL:AL096770 xref: EMBL:AL662781 xref: EMBL:AL662857 xref: EMBL:BK004441 xref: HGNC:HGNC:13971 xref: UniGene:Hs.632004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059120 ! O14J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018953 name: OR14K1_human def: "Olfactory receptor 14K1 gene" [UniProtKB:Q8NGZ2] synonym: "OR5AY1" EXACT [UniProtKB:Q8NGZ2] xref: EMBL:AB065624 xref: EMBL:AC118470 xref: EMBL:AF399590 xref: EMBL:BK004377 xref: EMBL:CH471148 xref: HGNC:HGNC:15025 xref: UniGene:Hs.553706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057790 ! O14K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018954 name: OR2A12_human def: "Olfactory receptor 2A12 gene" [UniProtKB:Q8NGT7] synonym: "OR2A12P" EXACT [UniProtKB:Q8NGT7] xref: EMBL:AB065694 xref: EMBL:BK004419 xref: HGNC:HGNC:15082 xref: UniGene:Hs.553708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057756 ! O2A12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018955 name: OR2A14_human def: "Olfactory receptor 2A14 gene" [UniProtKB:Q96R47] synonym: "OR2A14P" EXACT [UniProtKB:Q96R47] synonym: "OR2A6" EXACT [UniProtKB:Q96R47] xref: EMBL:AB065693 xref: EMBL:AF399596 xref: EMBL:BK004421 xref: HGNC:HGNC:15084 xref: UniGene:Hs.534547 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058363 ! O2A14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018956 name: OR2A25_human def: "Olfactory receptor 2A25 gene" [UniProtKB:A4D2G3] synonym: "OR2A25P" EXACT [UniProtKB:A4D2G3] synonym: "OR2A27" EXACT [UniProtKB:A4D2G3] xref: EMBL:CH236959 xref: HGNC:HGNC:19562 xref: UniGene:Hs.553787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053759 ! O2A25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018957 name: OR2AE1_human def: "Olfactory receptor 2AE1 gene" [UniProtKB:Q8NHA4] synonym: "OR2AE2" EXACT [UniProtKB:Q8NHA4] xref: EMBL:AB065478 xref: HGNC:HGNC:15087 xref: UniGene:Hs.647523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057861 ! O2AE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018958 name: OR2AG1_human def: "Olfactory receptor 2AG1 gene" [UniProtKB:Q9H205] synonym: "OR2AG3" EXACT [UniProtKB:Q9H205] xref: EMBL:AB065823 xref: EMBL:AF321237 xref: EMBL:AF399618 xref: HGNC:HGNC:15142 xref: UniGene:Hs.553608 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058668 ! O2AG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018959 name: OR2AG2_human def: "Olfactory receptor 2AG2 gene" [UniProtKB:A6NM03] synonym: "OR2AG2P" EXACT [UniProtKB:A6NM03] xref: EMBL:AC091564 xref: HGNC:HGNC:15143 xref: UniGene:Hs.534614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053902 ! O2AG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018960 name: OR2AJ1_human def: "Olfactory receptor 2AJ1 gene" [UniProtKB:Q8NGZ0] synonym: "OR2AJ1P" EXACT [UniProtKB:Q8NGZ0] xref: EMBL:AB065626 xref: HGNC:HGNC:15001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057789 ! O2AJ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018961 name: OR2AK2_human def: "Olfactory receptor 2AK2 gene" [UniProtKB:Q8NG84] synonym: "OR2AK1P" EXACT [UniProtKB:Q8NG84] xref: EMBL:AB065951 xref: EMBL:BK004457 xref: HGNC:HGNC:19569 xref: UniGene:Hs.690413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057622 ! O2AK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018962 name: OR2AP1_human def: "Olfactory receptor 2AP1 gene" [UniProtKB:Q8NGE2] synonym: "OR2AP1P" EXACT [UniProtKB:Q8NGE2] xref: EMBL:AB065868 xref: EMBL:BK004260 xref: HGNC:HGNC:15335 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057660 ! O2AP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018963 name: OR2AT4_human def: "Olfactory receptor 2AT4 gene" [UniProtKB:A6NND4] xref: EMBL:AP003175 xref: EMBL:BK004820 xref: HGNC:HGNC:19620 xref: UniGene:Hs.554515 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053914 ! O2AT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018964 name: OR2T10_human def: "Olfactory receptor 2T10 gene" [UniProtKB:Q8NGZ9] xref: EMBL:AB065616 xref: EMBL:BK004478 xref: HGNC:HGNC:19573 xref: UniGene:Hs.553585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057795 ! O2T10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018965 name: OR2T11_human def: "Olfactory receptor 2T11 gene" [UniProtKB:Q8NH01] xref: EMBL:AB065614 xref: EMBL:BK004476 xref: HGNC:HGNC:19574 xref: UniGene:Hs.626619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057797 ! O2T11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018966 name: OR2T12_human def: "Olfactory receptor 2T12 gene" [UniProtKB:Q8NG77] xref: EMBL:AB065960 xref: EMBL:AL450303 xref: EMBL:BK004485 xref: HGNC:HGNC:19592 xref: UniGene:Hs.553582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057618 ! O2T12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018967 name: OR2T27_human def: "Olfactory receptor 2T27 gene" [UniProtKB:Q8NH04] xref: EMBL:AB065611 xref: EMBL:BK004474 xref: HGNC:HGNC:31252 xref: UniGene:Hs.553814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057800 ! O2T27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018968 name: OR2T29_human def: "Olfactory receptor 2T29 gene" [UniProtKB:Q8NH02] xref: EMBL:AB065613 xref: HGNC:HGNC:31253 xref: UniGene:Hs.553707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057798 ! O2T29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018969 name: OR2T33_human def: "Olfactory receptor 2T33 gene" [UniProtKB:Q8NG76] xref: EMBL:AB065961 xref: EMBL:AL450303 xref: EMBL:BK004484 xref: HGNC:HGNC:31255 xref: UniGene:Hs.553783 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057617 ! O2T33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018970 name: OR2T34_human def: "Olfactory receptor 2T34 gene" [UniProtKB:Q8NGX1] xref: EMBL:AB065645 xref: EMBL:AC098483 xref: EMBL:AF399612 xref: EMBL:BK004477 xref: HGNC:HGNC:31256 xref: UniGene:Hs.553584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057773 ! O2T34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018971 name: OR2T35_human def: "Olfactory receptor 2T35 gene" [UniProtKB:Q8NGX2] xref: EMBL:AB065644 xref: EMBL:BK004475 xref: HGNC:HGNC:31257 xref: UniGene:Hs.534846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057774 ! O2T35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018972 name: OR4A15_human def: "Olfactory receptor 4A15 gene" [UniProtKB:Q8NGL6] xref: EMBL:AB065776 xref: EMBL:AF399578 xref: EMBL:BK004248 xref: HGNC:HGNC:15152 xref: UniGene:Hs.554529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057708 ! O4A15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018973 name: OR4A16_human def: "Olfactory receptor 4A16 gene" [UniProtKB:Q8NH70] xref: EMBL:AB065519 xref: EMBL:BK004249 xref: HGNC:HGNC:15153 xref: UniGene:Hs.554530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057841 ! O4A16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018974 name: OR4A47_human def: "Olfactory receptor 4A47 gene" [UniProtKB:Q6IF82] xref: EMBL:AC134982 xref: EMBL:BK004380 xref: HGNC:HGNC:31266 xref: UniGene:Hs.554532 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054094 ! A8MXA6_HUMAN relationship: codes_for CCO:B0056783 ! O4A47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018975 name: OR4C45_human def: "Olfactory receptor 4C45 gene" [UniProtKB:A6NMZ5] xref: EMBL:AC023080 xref: HGNC:HGNC:31270 xref: UniGene:Hs.554533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053910 ! O4C45_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018976 name: OR4C46_human def: "Olfactory receptor 4C46 gene" [UniProtKB:A6NHA9] xref: EMBL:AC126345 xref: HGNC:HGNC:31271 xref: UniGene:Hs.553564 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053845 ! O4C46_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018977 name: OR4F15_human def: "Olfactory receptor 4F15 gene" [UniProtKB:Q8NGB8] xref: EMBL:AB065900 xref: EMBL:AF399573 xref: EMBL:BK004405 xref: HGNC:HGNC:15078 xref: UniGene:Hs.554589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057643 ! O4F15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018978 name: OR4F17_human def: "Olfactory receptor 4F17 gene" [UniProtKB:Q8NGA8] synonym: "OR4F11P" EXACT [UniProtKB:Q8NGA8] synonym: "OR4F18" EXACT [UniProtKB:Q8NGA8] synonym: "OR4F19" EXACT [UniProtKB:Q8NGA8] xref: EMBL:AB065917 xref: HGNC:HGNC:15381 xref: UniGene:Hs.572591 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057636 ! O4F17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018979 name: OR4F21_human def: "Olfactory receptor 4F21 gene" [UniProtKB:O95013] synonym: "OR4F21P" EXACT [UniProtKB:O95013] xref: EMBL:AC004908 xref: EMBL:AC131281 xref: HGNC:HGNC:19583 xref: UniGene:Hs.690459 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054716 ! O4F21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018980 name: OR51A2_human def: "Olfactory receptor 51A2 gene" [UniProtKB:Q8NGJ7] xref: EMBL:AB065797 xref: HGNC:HGNC:14764 xref: UniGene:Hs.553805 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057693 ! O51A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018981 name: OR51A4_human def: "Olfactory receptor 51A4 gene" [UniProtKB:Q8NGJ6] xref: EMBL:AB065798 xref: HGNC:HGNC:14795 xref: UniGene:Hs.555481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057692 ! O51A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018982 name: OR51A7_human def: "Olfactory receptor 51A7 gene" [UniProtKB:Q8NH64] xref: EMBL:AB065525 xref: EMBL:AC018375 xref: HGNC:HGNC:15188 xref: UniGene:Hs.553560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054052 ! A8MV06_HUMAN relationship: codes_for CCO:B0054104 ! A8MXU4_HUMAN relationship: codes_for CCO:B0057838 ! O51A7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018983 name: OR51B2_human def: "Olfactory receptor 51B2 gene" [UniProtKB:Q9Y5P1] synonym: "OR51B1P" EXACT [UniProtKB:Q9Y5P1] xref: EMBL:AF137396 xref: EMBL:AF399503 xref: EMBL:BC117461 xref: HGNC:HGNC:14703 xref: UniGene:Hs.680163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056181 ! Q17R53_HUMAN relationship: codes_for CCO:B0059381 ! O51B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018984 name: OR51B4_human def: "Olfactory receptor 51B4 gene" [UniProtKB:Q9Y5P0] xref: EMBL:AF137396 xref: EMBL:BC069094 xref: HGNC:HGNC:14708 xref: UniGene:Hs.679499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059380 ! O51B4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018985 name: OR51B5_human def: "Olfactory receptor 51B5 gene" [UniProtKB:Q9H339] xref: EMBL:AF137396 xref: EMBL:BK004430 xref: HGNC:HGNC:19599 xref: UniGene:Hs.690458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058694 ! O51B5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018986 name: OR51B6_human def: "Olfactory receptor 51B5 gene" [UniProtKB:Q9H340] xref: EMBL:AC104389 xref: EMBL:AF137396 xref: HGNC:HGNC:19600 xref: UniGene:Hs.553730 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053834 ! A6NGT9_HUMAN relationship: codes_for CCO:B0058695 ! O51B6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018987 name: OR51D1_human def: "Olfactory receptor 51D1 gene" [UniProtKB:Q8NGF3] xref: EMBL:AB065855 xref: EMBL:BK004370 xref: HGNC:HGNC:15193 xref: UniGene:Hs.553728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057665 ! O51D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018988 name: OR51E1_human def: "Olfactory receptor 51E1 gene" [UniProtKB:Q8TCB6] synonym: "GPR164" EXACT [UniProtKB:Q8TCB6] synonym: "OR51E1P" EXACT [UniProtKB:Q8TCB6] synonym: "OR52A3P" EXACT [UniProtKB:Q8TCB6] synonym: "POGR" EXACT [UniProtKB:Q8TCB6] synonym: "PSGR2" EXACT [UniProtKB:Q8TCB6] xref: EMBL:AB065787 xref: EMBL:AY698056 xref: EMBL:AY775731 xref: EMBL:BC022401 xref: EMBL:BK004369 xref: HGNC:HGNC:15194 xref: UniGene:Hs.470038 xref: UniGene:Hs.669427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057913 ! O51E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018989 name: OR51E2_human def: "Olfactory receptor 51E2 gene" [UniProtKB:Q9H255] synonym: "PSGR" EXACT [UniProtKB:Q9H255] xref: EMBL:AF311306 xref: EMBL:AF369708 xref: EMBL:AY033942 xref: EMBL:BC020768 xref: EMBL:BK004368 xref: HGNC:HGNC:15195 xref: UniGene:Hs.501758 xref: UniGene:Hs.606330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058678 ! O51E2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018990 name: OR51F1_human def: "Olfactory receptor 51F1 gene" [UniProtKB:A6NGY5] synonym: "OR51F1P" EXACT [UniProtKB:A6NGY5] xref: EMBL:AC103710 xref: HGNC:HGNC:15196 xref: UniGene:Hs.553659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053835 ! O51F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018991 name: OR51G1_human def: "Olfactory receptor 51G1 gene" [UniProtKB:Q8NGK1] synonym: "OR51G3P" EXACT [UniProtKB:Q8NGK1] xref: EMBL:AB065793 xref: HGNC:HGNC:14738 xref: UniGene:Hs.554541 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057696 ! O51G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018992 name: OR51G2_human def: "Olfactory receptor 51G2 gene" [UniProtKB:Q8NGK0] xref: EMBL:AB065794 xref: HGNC:HGNC:15198 xref: UniGene:Hs.542302 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057695 ! O51G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018993 name: OR51H1P_human def: "Putative olfactory receptor 51H1 gene" [UniProtKB:Q8NH63] synonym: "OR51H1" EXACT [UniProtKB:Q8NH63] xref: EMBL:AB065527 xref: HGNC:HGNC:14833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057837 ! O51H1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018994 name: OR51I1_human def: "Olfactory receptor 51I1 gene" [UniProtKB:Q9H343] xref: EMBL:AC087380 xref: EMBL:AF137396 xref: EMBL:BK004429 xref: HGNC:HGNC:15200 xref: UniGene:Hs.553732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053783 ! A6NC31_HUMAN relationship: codes_for CCO:B0053861 ! A6NIH4_HUMAN relationship: codes_for CCO:B0058698 ! O51I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018995 name: OR51I2_human def: "Olfactory receptor 51I2 gene" [UniProtKB:Q9H344] xref: EMBL:AC087380 xref: EMBL:AF137396 xref: EMBL:BK004381 xref: HGNC:HGNC:15201 xref: UniGene:Hs.553733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054100 ! A8MXL5_HUMAN relationship: codes_for CCO:B0058699 ! O51I2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018996 name: OR51J1_human def: "Olfactory receptor 51J1 gene" [UniProtKB:Q9H342] synonym: "OR51J1P" EXACT [UniProtKB:Q9H342] synonym: "OR51J2" EXACT [UniProtKB:Q9H342] xref: EMBL:AC104389 xref: EMBL:AF137396 xref: HGNC:HGNC:14856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058697 ! O51J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018997 name: OR51L1_human def: "Olfactory receptor 51L1 gene" [UniProtKB:Q8NGJ5] xref: EMBL:AB065799 xref: HGNC:HGNC:14759 xref: UniGene:Hs.553559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057691 ! O51L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018998 name: OR51M1_human def: "Olfactory receptor 51M1 gene" [UniProtKB:Q9H341] xref: EMBL:AF137396 xref: EMBL:BK004382 xref: HGNC:HGNC:14847 xref: UniGene:Hs.553731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058696 ! O51M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0018999 name: OR51Q1_human def: "Olfactory receptor 51Q1 gene" [UniProtKB:Q8NH59] xref: EMBL:AB065531 xref: EMBL:AC087380 xref: HGNC:HGNC:14851 xref: UniGene:Hs.528592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057834 ! O51Q1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019000 name: OR51S1_human def: "Olfactory receptor 51S1 gene" [UniProtKB:Q8NGJ8] xref: EMBL:AB065796 xref: HGNC:HGNC:15204 xref: UniGene:Hs.553561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057694 ! O51S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019001 name: OR51V1_human def: "Olfactory receptor 51V1 gene" [UniProtKB:Q9H2C8] synonym: "OR51A12" EXACT [UniProtKB:Q9H2C8] xref: EMBL:AF289203 xref: EMBL:BK004432 xref: HGNC:HGNC:19597 xref: UniGene:Hs.553670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058683 ! O51V1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019002 name: OR52A1_human def: "Olfactory receptor 52A1 gene" [UniProtKB:Q9UKL2] xref: EMBL:AF154673 xref: EMBL:AF289204 xref: EMBL:BC111722 xref: EMBL:BK004431 xref: HGNC:HGNC:8318 xref: UniGene:Hs.553520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059195 ! O52A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019003 name: OR52A4_human def: "Putative olfactory receptor 52A4 gene" [UniProtKB:A6NMU1] xref: EMBL:AC113331 xref: HGNC:HGNC:19579 xref: UniGene:Hs.553729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053908 ! O52A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019004 name: OR52A5_human def: "Olfactory receptor 52A5 gene" [UniProtKB:Q9H2C5] xref: EMBL:AF289204 xref: EMBL:BK004433 xref: HGNC:HGNC:19580 xref: UniGene:Hs.546593 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058681 ! O52A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019005 name: OR52B4_human def: "Olfactory receptor 52B4 gene" [UniProtKB:Q8NGK2] xref: EMBL:AB065792 xref: EMBL:AC009758 xref: EMBL:BK004256 xref: EMBL:CH471064 xref: HGNC:HGNC:15209 xref: UniGene:Hs.447463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057697 ! O52B4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019006 name: OR52D1_human def: "Olfactory receptor 52D1 gene" [UniProtKB:Q9H346] xref: EMBL:AF137396 xref: EMBL:BK004276 xref: HGNC:HGNC:15212 xref: UniGene:Hs.553734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058701 ! O52D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019007 name: OR52E1_human def: "Olfactory receptor 52E1 gene" [UniProtKB:Q8NGJ3] synonym: "OR52E1P" EXACT [UniProtKB:Q8NGJ3] xref: EMBL:AB065801 xref: HGNC:HGNC:14766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057689 ! O52E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019008 name: OR52E2_human def: "Olfactory receptor 52E2 gene" [UniProtKB:Q8NGJ4] xref: EMBL:AB065800 xref: HGNC:HGNC:14769 xref: UniGene:Hs.553557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057690 ! O52E2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019009 name: OR52E4_human def: "Olfactory receptor 52E4 gene" [UniProtKB:Q8NGH9] xref: EMBL:AB065817 xref: HGNC:HGNC:15213 xref: UniGene:Hs.553739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057676 ! O52E4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019010 name: OR52E5_human def: "Olfactory receptor 52E5 gene" [UniProtKB:Q8NH55] xref: EMBL:AB065536 xref: HGNC:HGNC:15214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057830 ! O52E5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019011 name: OR52E6_human def: "Olfactory receptor 52E6 gene" [UniProtKB:Q96RD3] xref: EMBL:AB065815 xref: EMBL:AF399504 xref: HGNC:HGNC:15215 xref: UniGene:Hs.534693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058373 ! O52E6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019012 name: OR52E8_human def: "Olfactory receptor 52E8 gene" [UniProtKB:Q6IFG1] xref: EMBL:AC019088 xref: EMBL:BK004301 xref: HGNC:HGNC:15217 xref: UniGene:Hs.553738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056789 ! O52E8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019013 name: OR52I1_human def: "Olfactory receptor 52I1 gene" [UniProtKB:Q8NGK6] xref: EMBL:AB065788 xref: EMBL:BK004371 xref: HGNC:HGNC:15220 xref: UniGene:Hs.553727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057701 ! O52I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019014 name: OR52J3_human def: "Olfactory receptor 52J3 gene" [UniProtKB:Q8NH60] xref: EMBL:AB065530 xref: HGNC:HGNC:14799 xref: UniGene:Hs.553558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057835 ! O52J3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019015 name: OR52K1_human def: "Olfactory receptor 52K1 gene" [UniProtKB:Q8NGK4] xref: EMBL:AB065790 xref: HGNC:HGNC:15222 xref: UniGene:Hs.553726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057699 ! O52K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019016 name: OR52K2_human def: "Olfactory receptor 52K2 gene" [UniProtKB:Q8NGK3] xref: EMBL:AB065791 xref: EMBL:AC010930 xref: HGNC:HGNC:15223 xref: UniGene:Hs.553568 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054050 ! A8MUY8_HUMAN relationship: codes_for CCO:B0057698 ! O52K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019017 name: OR52M1_human def: "Olfactory receptor 52M1 gene" [UniProtKB:Q8NGK5] synonym: "OR52M1P" EXACT [UniProtKB:Q8NGK5] xref: EMBL:AB065789 xref: EMBL:BK004372 xref: HGNC:HGNC:15225 xref: UniGene:Hs.553567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057700 ! O52M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019018 name: OR52N1_human def: "Olfactory receptor 52N1 gene" [UniProtKB:Q8NH53] xref: EMBL:AB065538 xref: HGNC:HGNC:14853 xref: UniGene:Hs.690209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057828 ! O52N1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019019 name: OR52N2_human def: "Olfactory receptor 52N2 gene" [UniProtKB:Q8NGI0] xref: EMBL:AB065816 xref: HGNC:HGNC:15228 xref: UniGene:Hs.553737 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057677 ! O52N2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019020 name: OR52N4_human def: "Olfactory receptor 52N4 gene" [UniProtKB:Q8NGI2] xref: EMBL:AB065813 xref: EMBL:BK004385 xref: HGNC:HGNC:15230 xref: UniGene:Hs.553735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057679 ! O52N4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019021 name: OR52N5_human def: "Olfactory receptor 52N5 gene" [UniProtKB:Q8NH56] xref: EMBL:AB065535 xref: EMBL:AC131574 xref: EMBL:BC136981 xref: EMBL:BK004300 xref: EMBL:CH471064 xref: HGNC:HGNC:15231 xref: UniGene:Hs.690207 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054045 ! A8MUS4_HUMAN relationship: codes_for CCO:B0057831 ! O52N5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019022 name: OR52P1P_human def: "Putative olfactory receptor 52P1 gene" [UniProtKB:Q8NH57] synonym: "OR52P1" EXACT [UniProtKB:Q8NH57] xref: EMBL:AB065534 xref: HGNC:HGNC:15232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057832 ! O52P1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019023 name: OR52W1_human def: "Olfactory receptor 52W1 gene" [UniProtKB:Q6IF63] synonym: "OR52W1P" EXACT [UniProtKB:Q6IF63] xref: EMBL:AB065511 xref: EMBL:AC036216 xref: EMBL:BC137225 xref: EMBL:BK004399 xref: HGNC:HGNC:15239 xref: UniGene:Hs.553570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056780 ! O52W1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019024 name: OR52Z1_human def: "Olfactory receptor 52Z1 gene" [UniProtKB:P0C646] synonym: "OR52Z1P" EXACT [UniProtKB:P0C646] xref: EMBL:AC129505 xref: HGNC:HGNC:19596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054961 ! O52Z1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019025 name: OR56A3_human def: "Olfactory receptor 56A3 gene" [UniProtKB:Q8NH54] synonym: "OR56A3P" EXACT [UniProtKB:Q8NH54] synonym: "OR56A6" EXACT [UniProtKB:Q8NH54] xref: EMBL:AB065537 xref: EMBL:AC025016 xref: EMBL:BK004305 xref: HGNC:HGNC:14786 xref: UniGene:Hs.553741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057829 ! O56A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019026 name: OR56B1_human def: "Olfactory receptor 56B1 gene" [UniProtKB:Q8NGI3] synonym: "OR56B1P" EXACT [UniProtKB:Q8NGI3] xref: EMBL:AB065812 xref: EMBL:BK004386 xref: HGNC:HGNC:15245 xref: UniGene:Hs.689609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057680 ! O56B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019027 name: OR56B2P_human def: "Putative olfactory receptor 56B2 gene" [UniProtKB:Q8NGI1] xref: EMBL:AB065814 xref: HGNC:HGNC:15246 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057678 ! O56B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019028 name: OR56B4_human def: "Olfactory receptor 56B4 gene" [UniProtKB:Q8NH76] xref: EMBL:AB065513 xref: HGNC:HGNC:15248 xref: UniGene:Hs.632154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057847 ! O56B4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019029 name: OR5AL1_human def: "Olfactory receptor 5AL1 gene" [UniProtKB:P0C617] synonym: "OR5AL1P" EXACT [UniProtKB:P0C617] xref: EMBL:AF399353 xref: EMBL:BK004654 xref: HGNC:HGNC:14844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054956 ! O5AL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019030 name: OR5AN1_human def: "Olfactory receptor 5AN1 gene" [UniProtKB:Q8NGI8] xref: EMBL:AB065806 xref: EMBL:BK004508 xref: HGNC:HGNC:15255 xref: UniGene:Hs.553755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057685 ! O5AN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019031 name: OR6C65_human def: "Olfactory receptor 6C65 gene" [UniProtKB:A6NJZ3] xref: EMBL:AC125816 xref: HGNC:HGNC:31295 xref: UniGene:Hs.554553 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053875 ! O6C65_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019032 name: OR6C68_human def: "Olfactory receptor 6C68 gene" [UniProtKB:A6NDL8] xref: EMBL:AC122685 xref: EMBL:CH471054 xref: HGNC:HGNC:31297 xref: UniGene:Hs.626886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053793 ! O6C68_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019033 name: OR6C70_human def: "Olfactory receptor 6C70 gene" [UniProtKB:A6NIJ9] xref: EMBL:AC122685 xref: EMBL:CH471054 xref: HGNC:HGNC:31299 xref: UniGene:Hs.632718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053862 ! O6C70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019034 name: OR6C74_human def: "Olfactory receptor 6C74 gene" [UniProtKB:A6NCV1] xref: EMBL:AC122684 xref: EMBL:CH471054 xref: HGNC:HGNC:31303 xref: UniGene:Hs.554556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053786 ! O6C74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019035 name: OR6C75_human def: "Olfactory receptor 6C75 gene" [UniProtKB:A6NL08] xref: EMBL:AC125816 xref: EMBL:CH471054 xref: HGNC:HGNC:31304 xref: UniGene:Hs.554554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053890 ! O6C75_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019036 name: OR6C76_human def: "Olfactory receptor 6C76 gene" [UniProtKB:A6NM76] xref: EMBL:AC125816 xref: HGNC:HGNC:31305 xref: UniGene:Hs.553764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053904 ! O6C76_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019037 name: POU2AF1_human def: "POU domain class 2-associating factor 1 gene" [UniProtKB:Q16633] synonym: "OBF1" EXACT [UniProtKB:Q16633] xref: EMBL:BC032549 xref: EMBL:X83504 xref: EMBL:Z47550 xref: EMBL:Z49194 xref: HGNC:HGNC:9211 xref: UniGene:Hs.654525 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056165 ! OBF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019038 name: OCRL_human def: "Inositol polyphosphate 5-phosphatase OCRL-1 gene" [UniProtKB:Q01968] synonym: "INPP5F" EXACT [UniProtKB:Q01968] synonym: "OCRL1" EXACT [UniProtKB:Q01968] xref: EMBL:AL022162 xref: EMBL:AL138745 xref: EMBL:AL662877 xref: EMBL:BC130612 xref: EMBL:CH471107 xref: EMBL:M88162 xref: EMBL:S62085 xref: EMBL:U57627 xref: EMBL:Z73496 xref: HGNC:HGNC:8108 xref: UniGene:Hs.126357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053916 ! A6NNH7_HUMAN relationship: codes_for CCO:B0055698 ! OCRL_HUMAN relationship: codes_for CCO:B0056333 ! Q4VY10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019039 name: BCKDHA_human def: "2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor gene" [UniProtKB:P12694] xref: EMBL:BC007878 xref: EMBL:BC008933 xref: EMBL:BC023983 xref: EMBL:J04474 xref: EMBL:M22221 xref: EMBL:S38311 xref: EMBL:S38313 xref: EMBL:S38315 xref: EMBL:S38317 xref: EMBL:S38320 xref: EMBL:S38322 xref: EMBL:S38324 xref: EMBL:S38327 xref: EMBL:S62613 xref: EMBL:S62622 xref: EMBL:S62628 xref: EMBL:S62632 xref: EMBL:S62637 xref: EMBL:S62640 xref: EMBL:S62644 xref: EMBL:S62648 xref: EMBL:S62652 xref: EMBL:Z14093 xref: HGNC:HGNC:986 xref: UniGene:Hs.433307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055003 ! ODBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019040 name: POFUT1_human def: "GDP-fucose protein O-fucosyltransferase 1 precursor gene" [UniProtKB:Q9H488] synonym: "FUT12" EXACT [UniProtKB:Q9H488] synonym: "KIAA0180" EXACT [UniProtKB:Q9H488] xref: EMBL:AF375884 xref: EMBL:AL121897 xref: EMBL:BC000582 xref: EMBL:D80002 xref: HGNC:HGNC:14988 xref: UniGene:Hs.472409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058712 ! OFUT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019041 name: OGFR_human def: "Opioid growth factor receptor gene" [UniProtKB:Q9NZT2] xref: EMBL:AF109134 xref: EMBL:AF112980 xref: EMBL:AF172451 xref: EMBL:AF172452 xref: EMBL:AF172453 xref: EMBL:AK024485 xref: EMBL:AL035669 xref: EMBL:BC014137 xref: HGNC:HGNC:15768 xref: UniGene:Hs.67896 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059017 ! OGFR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019042 name: OLIG1_human def: "Oligodendrocyte transcription factor 1 gene" [UniProtKB:Q8TAK6] xref: EMBL:AL834450 xref: EMBL:AP000289 xref: EMBL:BC026989 xref: EMBL:BC033290 xref: EMBL:BK000278 xref: HGNC:HGNC:16983 xref: UniGene:Hs.56663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057888 ! OLIG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019043 name: OLIG2_human def: "Oligodendrocyte transcription factor 2 gene" [UniProtKB:Q13516] synonym: "BHLHB1" EXACT [UniProtKB:Q13516] synonym: "PRKCBP2" EXACT [UniProtKB:Q13516] synonym: "RACK17" EXACT [UniProtKB:Q13516] xref: EMBL:AF221520 xref: EMBL:BC047511 xref: EMBL:U48250 xref: HGNC:HGNC:9398 xref: UniGene:Hs.176977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055921 ! OLIG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019044 name: OLIG3_human def: "Oligodendrocyte transcription factor 3 gene" [UniProtKB:Q7RTU3] synonym: "BHLHB7" EXACT [UniProtKB:Q7RTU3] xref: EMBL:AK096362 xref: EMBL:AL023580 xref: EMBL:BC051352 xref: EMBL:BK000141 xref: HGNC:HGNC:18003 xref: UniGene:Hs.195398 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057134 ! OLIG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019045 name: OMP_human def: "Olfactory marker protein gene" [UniProtKB:P47874] xref: EMBL:BC069115 xref: EMBL:BC069365 xref: EMBL:U01212 xref: HGNC:HGNC:8136 xref: UniGene:Hs.673853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055387 ! OMP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019046 name: OSM_human def: "Oncostatin-M precursor gene" [UniProtKB:P13725] xref: EMBL:AC004264 xref: EMBL:BC011589 xref: EMBL:CR456534 xref: EMBL:M27286 xref: EMBL:M27287 xref: EMBL:M27288 xref: HGNC:HGNC:8506 xref: UniGene:Hs.248156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055018 ! ONCM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019047 name: OPA1_human def: "Dynamin-like 120 kDa protein, mitochondrial precursor gene" [UniProtKB:O60313] synonym: "KIAA0567" EXACT [UniProtKB:O60313] xref: EMBL:AB011139 xref: EMBL:AC048351 xref: EMBL:AC106710 xref: EMBL:AF416919 xref: EMBL:AF416920 xref: EMBL:BC075805 xref: HGNC:HGNC:8140 xref: UniGene:Hs.594504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054545 ! OPA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019048 name: OPHN1_human def: "Oligophrenin-1 gene" [UniProtKB:O60890] xref: EMBL:AB102656 xref: EMBL:AJ001189 xref: EMBL:AJ248245 xref: EMBL:AJ248246 xref: EMBL:AJ248247 xref: EMBL:AJ248248 xref: EMBL:AJ248249 xref: EMBL:AJ248250 xref: EMBL:AJ248251 xref: EMBL:AJ248252 xref: EMBL:AJ248253 xref: EMBL:AJ248254 xref: EMBL:AJ248255 xref: EMBL:AJ248256 xref: EMBL:AJ248257 xref: EMBL:AJ248258 xref: EMBL:AJ248259 xref: EMBL:AJ248260 xref: EMBL:AJ248261 xref: EMBL:AJ248262 xref: EMBL:AJ248263 xref: EMBL:AJ248264 xref: EMBL:AJ248265 xref: EMBL:AJ248266 xref: EMBL:AJ248267 xref: EMBL:AL157700 xref: EMBL:AL158201 xref: EMBL:AL672138 xref: EMBL:Z82203 xref: HGNC:HGNC:8148 xref: UniGene:Hs.128824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054586 ! OPHN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019049 name: OPN3_human def: "Opsin-3 gene" [UniProtKB:Q9H1Y3] synonym: "ECPN" EXACT [UniProtKB:Q9H1Y3] xref: EMBL:AF140242 xref: EMBL:AF303588 xref: EMBL:AF482426 xref: EMBL:AL133390 xref: EMBL:BC036773 xref: EMBL:BC062622 xref: EMBL:BC073872 xref: EMBL:CH471098 xref: HGNC:HGNC:14007 xref: UniGene:Hs.409081 xref: UniGene:Hs.534399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056734 ! Q6GMT1_HUMAN relationship: codes_for CCO:B0056890 ! Q6P5W7_HUMAN relationship: codes_for CCO:B0058667 ! OPN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019050 name: OPN5_human def: "Opsin-5 gene" [UniProtKB:Q6U736] synonym: "GPR136" EXACT [UniProtKB:Q6U736] synonym: "PGR12" EXACT [UniProtKB:Q6U736] synonym: "TMEM13" EXACT [UniProtKB:Q6U736] xref: EMBL:AL161622 xref: EMBL:AL356421 xref: EMBL:AY255615 xref: EMBL:AY288419 xref: EMBL:AY377391 xref: EMBL:BC126194 xref: EMBL:BC126198 xref: HGNC:HGNC:19992 xref: UniGene:Hs.213717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054066 ! A8MVV5_HUMAN relationship: codes_for CCO:B0056946 ! OPN5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019051 name: OPN1SW_human def: "Blue-sensitive opsin gene" [UniProtKB:P03999] synonym: "BCP" EXACT [UniProtKB:P03999] xref: EMBL:L32835 xref: EMBL:M13295 xref: EMBL:M13296 xref: EMBL:M13297 xref: EMBL:M13298 xref: EMBL:M13299 xref: EMBL:M26172 xref: EMBL:U53874 xref: HGNC:HGNC:1012 xref: UniGene:Hs.656404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054879 ! OPSB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019052 name: RHO_human def: "Rhodopsin gene" [UniProtKB:P08100] synonym: "OPN2" EXACT [UniProtKB:P08100] xref: EMBL:AB065668 xref: EMBL:BC112104 xref: EMBL:BC112106 xref: EMBL:BX537381 xref: EMBL:S81166 xref: EMBL:U16824 xref: EMBL:U49742 xref: HGNC:HGNC:10012 xref: UniGene:Hs.247565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054919 ! OPSD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019053 name: OPN1MW_human def: "Green-sensitive opsin gene" [UniProtKB:P04001] synonym: "GCP" EXACT [UniProtKB:P04001] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054881 ! OPSG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019054 name: OPN1MW2_human def: "Green-sensitive opsin gene" [UniProtKB:P04001] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054881 ! OPSG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019055 name: OPN1LW_human def: "Red-sensitive opsin gene" [UniProtKB:P04000] synonym: "RCP" EXACT [UniProtKB:P04000] xref: EMBL:M13300 xref: EMBL:M13301 xref: EMBL:M13302 xref: EMBL:M13303 xref: EMBL:M13304 xref: EMBL:M13305 xref: EMBL:Z68193 xref: HGNC:HGNC:9936 xref: UniGene:Hs.592247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054283 ! B1B1F0_HUMAN relationship: codes_for CCO:B0054880 ! OPSR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019056 name: OPTN_human def: "Optineurin gene" [UniProtKB:Q96CV9] synonym: "FIP2" EXACT [UniProtKB:Q96CV9] synonym: "GLC1E" EXACT [UniProtKB:Q96CV9] synonym: "HYPL" EXACT [UniProtKB:Q96CV9] synonym: "NRP" EXACT [UniProtKB:Q96CV9] xref: EMBL:AF049614 xref: EMBL:AF061034 xref: EMBL:AF283520 xref: EMBL:AF283521 xref: EMBL:AF283522 xref: EMBL:AF283523 xref: EMBL:AF283524 xref: EMBL:AF283525 xref: EMBL:AF283526 xref: EMBL:AF283527 xref: EMBL:AF420371 xref: EMBL:AF420372 xref: EMBL:AF420373 xref: EMBL:AL355355 xref: EMBL:BC013876 xref: EMBL:BC032762 xref: HGNC:HGNC:17142 xref: UniGene:Hs.498720 xref: UniGene:Hs.699222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030838 ! OPTN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019057 name: OR1A1_human def: "Olfactory receptor 1A1 gene" [UniProtKB:Q9P1Q5] xref: EMBL:AF087918 xref: EMBL:AF399555 xref: EMBL:BC141935 xref: EMBL:BK004241 xref: EMBL:CH471108 xref: HGNC:HGNC:8179 xref: UniGene:Hs.532688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059040 ! OR1A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019058 name: OR1A2_human def: "Olfactory receptor 1A2 gene" [UniProtKB:Q9Y585] xref: EMBL:AF155225 xref: EMBL:AF399556 xref: EMBL:BC069092 xref: EMBL:BC106733 xref: EMBL:BC106734 xref: EMBL:BK004242 xref: HGNC:HGNC:8180 xref: UniGene:Hs.532660 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059374 ! OR1A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019059 name: OR1B1_human def: "Olfactory receptor 1B1 gene" [UniProtKB:Q8NGR6] xref: EMBL:AB065723 xref: EMBL:AL162254 xref: EMBL:BK004229 xref: HGNC:HGNC:8181 xref: UniGene:Hs.553710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057741 ! OR1B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019060 name: OR1C1_human def: "Olfactory receptor 1C1 gene" [UniProtKB:Q15619] xref: EMBL:AB065625 xref: EMBL:AF399560 xref: EMBL:AL450999 xref: EMBL:BK004365 xref: EMBL:X89674 xref: HGNC:HGNC:8182 xref: UniGene:Hs.381306 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056080 ! OR1C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019061 name: OR1D2_human def: "Olfactory receptor 1D2 gene" [UniProtKB:P34982] synonym: "OLFR1" EXACT [UniProtKB:P34982] xref: EMBL:AF087917 xref: EMBL:AF399535 xref: EMBL:BC069552 xref: EMBL:BC106735 xref: EMBL:BC106736 xref: EMBL:BK004244 xref: EMBL:U04678 xref: EMBL:U53583 xref: EMBL:X65857 xref: HGNC:HGNC:8183 xref: UniGene:Hs.532771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028201 ! OR1D2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019062 name: OR1E1_human def: "Olfactory receptor 1E1 gene" [UniProtKB:P30953] synonym: "OR1E5" EXACT [UniProtKB:P30953] synonym: "OR1E6" EXACT [UniProtKB:P30953] synonym: "OR1E9P" EXACT [UniProtKB:P30953] xref: EMBL:AF052041 xref: EMBL:AF087916 xref: EMBL:AF095725 xref: EMBL:AF399550 xref: EMBL:BK004353 xref: EMBL:U04642 xref: EMBL:U04682 xref: EMBL:U78308 xref: EMBL:U86222 xref: EMBL:U86274 xref: EMBL:X64994 xref: HGNC:HGNC:8189 xref: UniGene:Hs.278485 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055227 ! OR1E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019063 name: OR1E3_human def: "Olfactory receptor 1E3 gene" [UniProtKB:Q8WZA6] synonym: "OR1E3P" EXACT [UniProtKB:Q8WZA6] xref: EMBL:AC097370 xref: EMBL:AF087929 xref: EMBL:AF399437 xref: EMBL:BK004549 xref: EMBL:U04690 xref: HGNC:HGNC:8191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058056 ! OR1E3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019064 name: OR1F1_human def: "Olfactory receptor 1F1 gene" [UniProtKB:O43749] synonym: "OLFMF" EXACT [UniProtKB:O43749] synonym: "OR1F10" EXACT [UniProtKB:O43749] synonym: "OR1F4" EXACT [UniProtKB:O43749] synonym: "OR1F5" EXACT [UniProtKB:O43749] synonym: "OR1F6" EXACT [UniProtKB:O43749] synonym: "OR1F7" EXACT [UniProtKB:O43749] synonym: "OR1F8" EXACT [UniProtKB:O43749] synonym: "OR1F9" EXACT [UniProtKB:O43749] xref: EMBL:AB065907 xref: EMBL:AF399559 xref: EMBL:AJ003147 xref: EMBL:BC069335 xref: EMBL:BK004247 xref: EMBL:U86234 xref: EMBL:Y14442 xref: HGNC:HGNC:8194 xref: UniGene:Hs.664502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054518 ! OR1F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019065 name: OR1F2_human def: "Olfactory receptor 1F2 gene" [UniProtKB:Q96R84] xref: EMBL:AF399558 xref: EMBL:AJ003145 xref: HGNC:HGNC:8196 xref: UniGene:Hs.651203 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058369 ! OR1F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019066 name: OR1F12_human def: "Olfactory receptor 1F12 gene" [UniProtKB:Q8NHA8] synonym: "OR1F12P" EXACT [UniProtKB:Q8NHA8] xref: EMBL:AB065468 xref: HGNC:HGNC:13964 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057864 ! OR1FC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019067 name: OR1G1_human def: "Olfactory receptor 1G1 gene" [UniProtKB:P47890] synonym: "OR1G2" EXACT [UniProtKB:P47890] xref: EMBL:AF087928 xref: EMBL:BC069379 xref: EMBL:BC095520 xref: EMBL:U04689 xref: EMBL:U53583 xref: HGNC:HGNC:8204 xref: UniGene:Hs.248183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055390 ! OR1G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019068 name: OR1I1_human def: "Olfactory receptor 1I1 gene" [UniProtKB:O60431] xref: EMBL:AC004794 xref: EMBL:AF399548 xref: HGNC:HGNC:8207 xref: UniGene:Hs.631610 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054558 ! OR1I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019069 name: OR1J1_human def: "Olfactory receptor 1J1 gene" [UniProtKB:Q8NGS3] xref: EMBL:AB065716 xref: EMBL:AF399554 xref: EMBL:AL353767 xref: EMBL:BK004452 xref: HGNC:HGNC:8208 xref: UniGene:Hs.632692 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057746 ! OR1J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019070 name: OR1J2_human def: "Olfactory receptor 1J2 gene" [UniProtKB:Q8NGS2] synonym: "OR1J3" EXACT [UniProtKB:Q8NGS2] synonym: "OR1J5" EXACT [UniProtKB:Q8NGS2] xref: EMBL:AB065717 xref: EMBL:AF179767 xref: EMBL:AF399552 xref: EMBL:BK004448 xref: EMBL:X64989 xref: HGNC:HGNC:8209 xref: UniGene:Hs.460145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057745 ! OR1J2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019071 name: OR1J4_human def: "Olfactory receptor 1J4 gene" [UniProtKB:Q8NGS1] xref: EMBL:AB065718 xref: EMBL:AF399553 xref: EMBL:BK004469 xref: EMBL:X64979 xref: HGNC:HGNC:8211 xref: UniGene:Hs.632679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057744 ! OR1J4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019072 name: OR1K1_human def: "Olfactory receptor 1K1 gene" [UniProtKB:Q8NGR3] xref: EMBL:AB065726 xref: EMBL:AF399622 xref: EMBL:AL359512 xref: HGNC:HGNC:8212 xref: UniGene:Hs.632681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057739 ! OR1K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019073 name: OR1L3_human def: "Olfactory receptor 1L3 gene" [UniProtKB:Q8NH93] xref: EMBL:AB065492 xref: EMBL:AL162254 xref: EMBL:BK004231 xref: HGNC:HGNC:8215 xref: UniGene:Hs.626839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057859 ! OR1L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019074 name: OR1L4_human def: "Olfactory receptor 1L4 gene" [UniProtKB:Q8NGR5] synonym: "OR1L5" EXACT [UniProtKB:Q8NGR5] xref: EMBL:AB065724 xref: EMBL:AF399562 xref: HGNC:HGNC:8216 xref: UniGene:Hs.626838 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057740 ! OR1L4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019075 name: OR1L8_human def: "Olfactory receptor 1L8 gene" [UniProtKB:Q8NGR8] xref: EMBL:AB065721 xref: EMBL:AF399564 xref: EMBL:BK004447 xref: HGNC:HGNC:15110 xref: UniGene:Hs.632695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057742 ! OR1L8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019076 name: OR1M1_human def: "Olfactory receptor 1M1 gene" [UniProtKB:Q8NGA1] xref: EMBL:AB065925 xref: EMBL:AF399549 xref: HGNC:HGNC:8220 xref: UniGene:Hs.553577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057630 ! OR1M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019077 name: OR1N1_human def: "Olfactory receptor 1N1 gene" [UniProtKB:Q8NGS0] synonym: "OR1N3" EXACT [UniProtKB:Q8NGS0] xref: EMBL:AB065719 xref: EMBL:AF399547 xref: EMBL:BK004446 xref: EMBL:U86216 xref: HGNC:HGNC:8221 xref: UniGene:Hs.553604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057743 ! OR1N1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019078 name: OR1P1_human def: "Olfactory receptor 1P1 gene" [UniProtKB:Q8NH06] synonym: "OR1P1P" EXACT [UniProtKB:Q8NH06] xref: EMBL:AB065608 xref: EMBL:AF087927 xref: EMBL:AF399436 xref: EMBL:BK004548 xref: HGNC:HGNC:8222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057802 ! OR1P1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019079 name: OR1Q1_human def: "Olfactory receptor 1Q1 gene" [UniProtKB:Q15612] synonym: "OR1Q2" EXACT [UniProtKB:Q15612] synonym: "OR1Q3" EXACT [UniProtKB:Q15612] xref: EMBL:AB065722 xref: EMBL:AF399561 xref: EMBL:AL162254 xref: EMBL:BK004228 xref: EMBL:X89667 xref: HGNC:HGNC:8223 xref: UniGene:Hs.684864 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056078 ! OR1Q1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019080 name: OR2A2_human def: "Olfactory receptor 2A2 gene" [UniProtKB:Q6IF42] synonym: "OR2A17P" EXACT [UniProtKB:Q6IF42] synonym: "OR2A2P" EXACT [UniProtKB:Q6IF42] xref: EMBL:AB065695 xref: EMBL:AC091768 xref: EMBL:BK004420 xref: HGNC:HGNC:8230 xref: UniGene:Hs.553841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056778 ! OR2A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019081 name: OR2A4_human def: "Olfactory receptor 2A4 gene" [UniProtKB:O95047] synonym: "OR2A10" EXACT [UniProtKB:O95047] xref: EMBL:AC005587 xref: EMBL:AL135904 xref: EMBL:BC120953 xref: EMBL:BC120954 xref: EMBL:BK004444 xref: HGNC:HGNC:14729 xref: UniGene:Hs.486488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054717 ! OR2A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019082 name: OR2A5_human def: "Olfactory receptor 2A5 gene" [UniProtKB:Q96R48] synonym: "OR2A26" EXACT [UniProtKB:Q96R48] synonym: "OR2A8" EXACT [UniProtKB:Q96R48] xref: EMBL:AC091768 xref: EMBL:AF399595 xref: EMBL:U86278 xref: EMBL:U86281 xref: HGNC:HGNC:8232 xref: UniGene:Hs.553793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058364 ! OR2A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019083 name: OR2A7_human def: "Olfactory receptor 2A7 gene" [UniProtKB:Q96R45] xref: EMBL:AC004889 xref: EMBL:AF399598 xref: EMBL:BK004218 xref: HGNC:HGNC:8234 xref: UniGene:Hs.490448 xref: UniGene:Hs.658609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058362 ! OR2A7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019084 name: OR2B2_human def: "Olfactory receptor 2B2 gene" [UniProtKB:Q9GZK3] synonym: "OR2B9" EXACT [UniProtKB:Q9GZK3] xref: EMBL:AJ302584 xref: EMBL:AJ302585 xref: EMBL:AJ302586 xref: EMBL:AJ302587 xref: EMBL:AJ302588 xref: EMBL:AJ302589 xref: EMBL:AJ302590 xref: EMBL:AJ302591 xref: EMBL:AJ302592 xref: EMBL:AJ302593 xref: EMBL:Z98744 xref: HGNC:HGNC:13966 xref: UniGene:Hs.553551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058624 ! OR2B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019085 name: OR2B3P_human def: "Putative olfactory receptor 2B3 gene" [UniProtKB:O76000] synonym: "OR2B3" EXACT [UniProtKB:O76000] xref: EMBL:AF399632 xref: EMBL:AJ302537 xref: EMBL:AJ302538 xref: EMBL:AJ302539 xref: EMBL:AJ302540 xref: EMBL:AJ302541 xref: EMBL:AJ302542 xref: EMBL:AJ302543 xref: EMBL:AJ302544 xref: EMBL:AJ302545 xref: EMBL:AJ302546 xref: EMBL:AL022727 xref: EMBL:AL662791 xref: EMBL:AL662852 xref: EMBL:AL929561 xref: EMBL:BK004436 xref: HGNC:HGNC:8238 xref: UniGene:Hs.553835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054684 ! OR2B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019086 name: OR2B6_human def: "Olfactory receptor 2B6 gene" [UniProtKB:P58173] synonym: "OR2B1" EXACT [UniProtKB:P58173] synonym: "OR2B1P" EXACT [UniProtKB:P58173] synonym: "OR2B5" EXACT [UniProtKB:P58173] synonym: "OR2B6P" EXACT [UniProtKB:P58173] xref: EMBL:AL133267 xref: EMBL:BC109251 xref: EMBL:BC110457 xref: EMBL:BK004373 xref: EMBL:U86270 xref: HGNC:HGNC:8241 xref: UniGene:Hs.532145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055565 ! OR2B6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019087 name: OR2B8P_human def: "Putative olfactory receptor 2B8 gene" [UniProtKB:P59922] synonym: "OR2B8" EXACT [UniProtKB:P59922] xref: EMBL:AC025941 xref: HGNC:HGNC:13968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055592 ! OR2B8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019088 name: OR2B11_human def: "Olfactory receptor 2B11 gene" [UniProtKB:Q5JQS5] xref: EMBL:AL606804 xref: HGNC:HGNC:31249 xref: UniGene:Hs.446999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056459 ! OR2BB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019089 name: OR2C1_human def: "Olfactory receptor 2C1 gene" [UniProtKB:O95371] synonym: "OR2C2P" EXACT [UniProtKB:O95371] xref: EMBL:AF098664 xref: EMBL:BC069456 xref: EMBL:BK004407 xref: EMBL:BK004428 xref: HGNC:HGNC:8242 xref: UniGene:Hs.258574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054752 ! OR2C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019090 name: OR2C3_human def: "Olfactory receptor 2C3 gene" [UniProtKB:Q8N628] synonym: "OR2C4" EXACT [UniProtKB:Q8N628] synonym: "OR2C5P" EXACT [UniProtKB:Q8N628] xref: EMBL:AB065649 xref: EMBL:AL606804 xref: EMBL:BC030717 xref: HGNC:HGNC:15005 xref: UniGene:Hs.23491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057483 ! OR2C3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019091 name: OR2D2_human def: "Olfactory receptor 2D2 gene" [UniProtKB:Q9H210] synonym: "OR2D1" EXACT [UniProtKB:Q9H210] xref: EMBL:AB065824 xref: EMBL:AF065876 xref: EMBL:AF321237 xref: EMBL:AF399591 xref: EMBL:BK004434 xref: HGNC:HGNC:8244 xref: UniGene:Hs.690210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058672 ! OR2D2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019092 name: OR2F1_human def: "Olfactory receptor 2F1 gene" [UniProtKB:Q13607] synonym: "OLF3" EXACT [UniProtKB:Q13607] synonym: "OR2F3" EXACT [UniProtKB:Q13607] synonym: "OR2F3P" EXACT [UniProtKB:Q13607] synonym: "OR2F4" EXACT [UniProtKB:Q13607] synonym: "OR2F5" EXACT [UniProtKB:Q13607] xref: EMBL:AC004853 xref: EMBL:AF399594 xref: EMBL:BC104975 xref: EMBL:BK004215 xref: EMBL:U56421 xref: HGNC:HGNC:8246 xref: UniGene:Hs.553595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055934 ! OR2F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019093 name: OR2F2_human def: "Olfactory receptor 2F2 gene" [UniProtKB:O95006] xref: EMBL:AC004853 xref: EMBL:BK004214 xref: HGNC:HGNC:8247 xref: UniGene:Hs.553596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054715 ! OR2F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019094 name: OR2G2_human def: "Olfactory receptor 2G2 gene" [UniProtKB:Q8NGZ5] xref: EMBL:AB065621 xref: EMBL:AL606804 xref: EMBL:BK004472 xref: HGNC:HGNC:15007 xref: UniGene:Hs.690208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057793 ! OR2G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019095 name: OR2G3_human def: "Olfactory receptor 2G3 gene" [UniProtKB:Q8NGZ4] xref: EMBL:AB065622 xref: EMBL:AL606804 xref: EMBL:BK004417 xref: HGNC:HGNC:15008 xref: UniGene:Hs.653227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057792 ! OR2G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019096 name: OR2G6_human def: "Olfactory receptor 2G6 gene" [UniProtKB:Q5TZ20] xref: EMBL:BX537158 xref: HGNC:HGNC:27019 xref: UniGene:Hs.553784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056637 ! OR2G6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019097 name: OR2H1_human def: "Olfactory receptor 2H1 gene" [UniProtKB:Q9GZK4] synonym: "OR2H6" EXACT [UniProtKB:Q9GZK4] synonym: "OR2H8" EXACT [UniProtKB:Q9GZK4] xref: EMBL:AF042078 xref: EMBL:AF044491 xref: EMBL:AF044492 xref: EMBL:AJ302604 xref: EMBL:AJ302605 xref: EMBL:AJ302606 xref: EMBL:AJ302607 xref: EMBL:AJ302608 xref: EMBL:AJ302609 xref: EMBL:AJ302610 xref: EMBL:AJ302611 xref: EMBL:AJ302612 xref: EMBL:AJ302613 xref: EMBL:AJ459847 xref: EMBL:AL035542 xref: EMBL:AL645927 xref: EMBL:AL662869 xref: EMBL:BC048991 xref: EMBL:BK004209 xref: EMBL:BX000531 xref: EMBL:BX247947 xref: HGNC:HGNC:8252 xref: UniGene:Hs.434715 xref: UniGene:Hs.706556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058625 ! OR2H1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019098 name: OR2H2_human def: "Olfactory receptor 2H2 gene" [UniProtKB:O95918] synonym: "FAT11" EXACT [UniProtKB:O95918] synonym: "OLFR2" EXACT [UniProtKB:O95918] synonym: "OR2H3" EXACT [UniProtKB:O95918] xref: EMBL:AB065965 xref: EMBL:AF211939 xref: EMBL:AF211940 xref: EMBL:AF211941 xref: EMBL:AF211942 xref: EMBL:AF399631 xref: EMBL:AL031983 xref: EMBL:AL645936 xref: EMBL:AL662826 xref: EMBL:BC069146 xref: EMBL:BC101683 xref: EMBL:BC112176 xref: EMBL:BK004225 xref: EMBL:BX000688 xref: EMBL:BX927223 xref: EMBL:CH471081 xref: EMBL:CR759766 xref: EMBL:CR759870 xref: EMBL:CR788300 xref: EMBL:L35475 xref: HGNC:HGNC:8253 xref: UniGene:Hs.529493 xref: UniGene:Hs.697691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054804 ! OR2H2_HUMAN relationship: codes_for CCO:B0056541 ! Q5SUK1_HUMAN relationship: codes_for CCO:B0056812 ! Q6IFN7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019099 name: OR2I1P_human def: "Putative olfactory receptor 2I1 gene" [UniProtKB:Q8NGU4] synonym: "OR2I2" EXACT [UniProtKB:Q8NGU4] synonym: "OR2I3P" EXACT [UniProtKB:Q8NGU4] synonym: "OR2I4P" EXACT [UniProtKB:Q8NGU4] xref: EMBL:AB065686 xref: HGNC:HGNC:8258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057762 ! OR2I1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019100 name: OR2J1_human def: "Olfactory receptor 2J1 gene" [UniProtKB:Q9GZK6] synonym: "OR2J1P" EXACT [UniProtKB:Q9GZK6] xref: EMBL:AJ302565 xref: EMBL:AJ302566 xref: EMBL:AJ302567 xref: EMBL:AJ302568 xref: EMBL:AJ302569 xref: EMBL:AJ302570 xref: EMBL:AL645937 xref: EMBL:CR933783 xref: HGNC:HGNC:8259 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054189 ! B0V1T2_HUMAN relationship: codes_for CCO:B0058626 ! OR2J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019101 name: OR2J2_human def: "Olfactory receptor 2J2 gene" [UniProtKB:O76002] xref: EMBL:AJ302571 xref: EMBL:AJ302572 xref: EMBL:AJ302573 xref: EMBL:AJ302574 xref: EMBL:AJ302575 xref: EMBL:AJ302576 xref: EMBL:AJ302577 xref: EMBL:AJ302578 xref: EMBL:AJ302579 xref: EMBL:AJ302580 xref: EMBL:AJ302581 xref: EMBL:AJ302582 xref: EMBL:AJ302583 xref: EMBL:AL022727 xref: EMBL:AL645937 xref: EMBL:AL662852 xref: EMBL:AL935156 xref: EMBL:BC069121 xref: EMBL:BC108896 xref: EMBL:BC108897 xref: EMBL:BC108898 xref: EMBL:BC108899 xref: EMBL:BK004438 xref: EMBL:BX248093 xref: EMBL:CR759834 xref: HGNC:HGNC:8260 xref: UniGene:Hs.163518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054686 ! OR2J2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019102 name: OR2J3_human def: "Olfactory receptor 2J3 gene" [UniProtKB:O76001] xref: EMBL:AF399630 xref: EMBL:AJ302547 xref: EMBL:AJ302548 xref: EMBL:AJ302549 xref: EMBL:AJ302550 xref: EMBL:AJ302551 xref: EMBL:AJ302552 xref: EMBL:AJ302553 xref: EMBL:AJ302554 xref: EMBL:AJ302555 xref: EMBL:AJ302556 xref: EMBL:AJ302557 xref: EMBL:AJ302558 xref: EMBL:AL022727 xref: EMBL:AL645937 xref: EMBL:AL662852 xref: EMBL:AL929561 xref: EMBL:BK004437 xref: EMBL:BX248093 xref: EMBL:CR933783 xref: HGNC:HGNC:8261 xref: UniGene:Hs.553836 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054190 ! B0V1T3_HUMAN relationship: codes_for CCO:B0054685 ! OR2J3_HUMAN relationship: codes_for CCO:B0056540 ! Q5SUJ7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019103 name: OR2K2_human def: "Olfactory receptor 2K2 gene" [UniProtKB:Q8NGT1] synonym: "OR2AR1P" EXACT [UniProtKB:Q8NGT1] xref: EMBL:AB065707 xref: EMBL:AL354661 xref: EMBL:BC111086 xref: HGNC:HGNC:8264 xref: UniGene:Hs.381312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057753 ! OR2K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019104 name: OR2L2_human def: "Olfactory receptor 2L2 gene" [UniProtKB:Q8NH16] synonym: "OR2L12" EXACT [UniProtKB:Q8NH16] synonym: "OR2L4P" EXACT [UniProtKB:Q8NH16] xref: EMBL:AB065597 xref: EMBL:BC104792 xref: EMBL:BC104794 xref: EMBL:X64978 xref: HGNC:HGNC:8266 xref: UniGene:Hs.684888 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057808 ! OR2L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019105 name: OR2L3_human def: "Olfactory receptor 2L3 gene" [UniProtKB:Q8NG85] xref: EMBL:AB065950 xref: HGNC:HGNC:15009 xref: UniGene:Hs.690412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057623 ! OR2L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019106 name: OR2L5_human def: "Olfactory receptor 2L5 gene" [UniProtKB:Q8NG80] synonym: "OR2L11" EXACT [UniProtKB:Q8NG80] xref: EMBL:AB065956 xref: EMBL:BK004458 xref: HGNC:HGNC:15011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057619 ! OR2L5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019107 name: OR2L8_human def: "Olfactory receptor 2L8 gene" [UniProtKB:Q8NGY9] xref: EMBL:AB065627 xref: EMBL:BK004459 xref: HGNC:HGNC:15014 xref: UniGene:Hs.690212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057788 ! OR2L8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019108 name: OR2L13_human def: "Olfactory receptor 2L13 gene" [UniProtKB:Q8N349] synonym: "OR2L14" EXACT [UniProtKB:Q8N349] xref: EMBL:AL513488 xref: EMBL:BC028158 xref: HGNC:HGNC:19578 xref: UniGene:Hs.372936 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057453 ! OR2LD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019109 name: OR2M2_human def: "Olfactory receptor 2M2 gene" [UniProtKB:Q96R28] xref: EMBL:AF399616 xref: EMBL:AL592313 xref: HGNC:HGNC:8268 xref: UniGene:Hs.534728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058360 ! OR2M2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019110 name: OR2M3_human def: "Olfactory receptor 2M3 gene" [UniProtKB:Q8NG83] synonym: "OR2M3P" EXACT [UniProtKB:Q8NG83] synonym: "OR2M6" EXACT [UniProtKB:Q8NG83] xref: EMBL:AB065952 xref: EMBL:AL450303 xref: EMBL:BK004482 xref: HGNC:HGNC:8269 xref: UniGene:Hs.553581 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057621 ! OR2M3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019111 name: OR2M4_human def: "Olfactory receptor 2M4 gene" [UniProtKB:Q96R27] xref: EMBL:AB065953 xref: EMBL:AF399617 xref: EMBL:AL450303 xref: EMBL:BK004483 xref: EMBL:X64992 xref: EMBL:X89666 xref: HGNC:HGNC:8270 xref: UniGene:Hs.381309 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058359 ! OR2M4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019112 name: OR2M5_human def: "Olfactory receptor 2M5 gene" [UniProtKB:A3KFT3] synonym: "OR2M5P" EXACT [UniProtKB:A3KFT3] xref: EMBL:AL592313 xref: HGNC:HGNC:19576 xref: UniGene:Hs.553580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053742 ! OR2M5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019113 name: OR2M7_human def: "Olfactory receptor 2M7 gene" [UniProtKB:Q8NG81] xref: EMBL:AB065954 xref: EMBL:AL450303 xref: EMBL:BK004486 xref: HGNC:HGNC:19594 xref: UniGene:Hs.530570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057620 ! OR2M7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019114 name: OR2S2_human def: "Olfactory receptor 2S2 gene" [UniProtKB:Q9NQN1] xref: EMBL:AF399601 xref: EMBL:AL135841 xref: EMBL:BC104869 xref: EMBL:BC113651 xref: EMBL:BK004443 xref: HGNC:HGNC:8276 xref: UniGene:Hs.553540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058869 ! OR2S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019115 name: OR2T1_human def: "Olfactory receptor 2T1 gene" [UniProtKB:O43869] xref: EMBL:AF399613 xref: EMBL:BK004463 xref: EMBL:U86215 xref: HGNC:HGNC:8277 xref: UniGene:Hs.626885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054528 ! OR2T1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019116 name: OR2T2_human def: "Olfactory receptor 2T2 gene" [UniProtKB:Q6IF00] synonym: "OR2T2P" EXACT [UniProtKB:Q6IF00] xref: EMBL:AC138089 xref: EMBL:BK004462 xref: HGNC:HGNC:14725 xref: UniGene:Hs.554482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056772 ! OR2T2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019117 name: OR2T3_human def: "Olfactory receptor 2T3 gene" [UniProtKB:Q8NH03] xref: EMBL:AB065612 xref: EMBL:AC138089 xref: HGNC:HGNC:14727 xref: UniGene:Hs.554481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057799 ! OR2T3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019118 name: OR2T4_human def: "Olfactory receptor 2T4 gene" [UniProtKB:Q8NH00] xref: EMBL:AB065615 xref: EMBL:BK004464 xref: HGNC:HGNC:15016 xref: UniGene:Hs.553586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057796 ! OR2T4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019119 name: OR2T5_human def: "Olfactory receptor 2T5 gene" [UniProtKB:Q6IEZ7] xref: EMBL:AC138089 xref: EMBL:BK004465 xref: HGNC:HGNC:15017 xref: UniGene:Hs.553808 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056771 ! OR2T5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019120 name: OR2T6_human def: "Olfactory receptor 2T6 gene" [UniProtKB:Q8NHC8] synonym: "OR2T6P" EXACT [UniProtKB:Q8NHC8] synonym: "OR2T9" EXACT [UniProtKB:Q8NHC8] xref: EMBL:AB065438 xref: EMBL:AC138089 xref: HGNC:HGNC:15018 xref: UniGene:Hs.626884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057874 ! OR2T6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019121 name: OR2T8_human def: "Olfactory receptor 2T8 gene" [UniProtKB:A6NH00] synonym: "OR2T8P" EXACT [UniProtKB:A6NH00] xref: EMBL:AC099571 xref: HGNC:HGNC:15020 xref: UniGene:Hs.521114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053836 ! OR2T8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019122 name: OR2V1_human def: "Olfactory receptor 2V1 gene" [UniProtKB:Q8NHB1] xref: EMBL:AB065465 xref: EMBL:AC008620 xref: HGNC:HGNC:8280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057866 ! OR2V1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019123 name: OR2V2_human def: "Olfactory receptor 2V2 gene" [UniProtKB:Q96R30] synonym: "OR2V3" EXACT [UniProtKB:Q96R30] xref: EMBL:AB065675 xref: EMBL:AF399614 xref: EMBL:BK004246 xref: HGNC:HGNC:15341 xref: UniGene:Hs.553681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058361 ! OR2V2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019124 name: OR2W1_human def: "Olfactory receptor 2W1 gene" [UniProtKB:Q9Y3N9] xref: EMBL:AF399628 xref: EMBL:AJ302594 xref: EMBL:AJ302595 xref: EMBL:AJ302596 xref: EMBL:AJ302597 xref: EMBL:AJ302598 xref: EMBL:AJ302599 xref: EMBL:AJ302600 xref: EMBL:AJ302601 xref: EMBL:AJ302602 xref: EMBL:AJ302603 xref: EMBL:AL035402 xref: EMBL:AL662791 xref: EMBL:AL662865 xref: EMBL:AL929561 xref: EMBL:BC103870 xref: EMBL:BC103871 xref: EMBL:BC103872 xref: EMBL:BK004522 xref: EMBL:BX248413 xref: HGNC:HGNC:8281 xref: UniGene:Hs.553526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059341 ! OR2W1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019125 name: OR2W3_human def: "Olfactory receptor 2W3 gene" [UniProtKB:Q7Z3T1] synonym: "OR2W3P" EXACT [UniProtKB:Q7Z3T1] synonym: "OR2W8P" EXACT [UniProtKB:Q7Z3T1] xref: EMBL:AB065949 xref: EMBL:BK004456 xref: EMBL:BX537432 xref: HGNC:HGNC:15021 xref: UniGene:Hs.269151 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057154 ! OR2W3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019126 name: OR2Y1_human def: "Olfactory receptor 2Y1 gene" [UniProtKB:Q8NGV0] xref: EMBL:AB065676 xref: EMBL:AF399629 xref: EMBL:BK004351 xref: HGNC:HGNC:14837 xref: UniGene:Hs.554719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057766 ! OR2Y1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019127 name: OR2Z1_human def: "Olfactory receptor 2Z1 gene" [UniProtKB:Q8NG97] synonym: "OR2Z2" EXACT [UniProtKB:Q8NG97] xref: EMBL:AB065930 xref: EMBL:AF399619 xref: EMBL:BK004262 xref: HGNC:HGNC:15391 xref: UniGene:Hs.553675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057627 ! OR2Z1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019128 name: OR3A1_human def: "Olfactory receptor 3A1 gene" [UniProtKB:P47881] synonym: "OLFRA03" EXACT [UniProtKB:P47881] xref: EMBL:AC087498 xref: EMBL:AF087924 xref: EMBL:BC069414 xref: EMBL:BC096187 xref: EMBL:BC096188 xref: EMBL:BC096189 xref: EMBL:BC096190 xref: EMBL:BK004238 xref: EMBL:U04683 xref: EMBL:U58675 xref: EMBL:X80391 xref: HGNC:HGNC:8282 xref: UniGene:Hs.647410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055388 ! OR3A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019129 name: OR3A2_human def: "Olfactory receptor 3A2 gene" [UniProtKB:P47893] synonym: "OLFRA04" EXACT [UniProtKB:P47893] xref: EMBL:AF087930 xref: EMBL:U04713 xref: HGNC:HGNC:8283 xref: UniGene:Hs.647414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055391 ! OR3A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019130 name: OR3A4_human def: "Olfactory receptor 3A4 gene" [UniProtKB:P47883] synonym: "OR3A4P" EXACT [UniProtKB:P47883] synonym: "OR3A5P" EXACT [UniProtKB:P47883] xref: EMBL:AF399621 xref: EMBL:U04680 xref: HGNC:HGNC:15510 xref: UniGene:Hs.632245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055389 ! OR3A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019131 name: OR4A4P_human def: "Putative olfactory receptor 4A4 gene" [UniProtKB:Q8NGN8] xref: EMBL:AB065752 xref: EMBL:AF399577 xref: EMBL:BK004379 xref: HGNC:HGNC:15161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057725 ! OR4A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019132 name: OR4A5_human def: "Olfactory receptor 4A5 gene" [UniProtKB:Q8NH83] xref: EMBL:AB065506 xref: EMBL:AC026076 xref: EMBL:BK004378 xref: HGNC:HGNC:15162 xref: UniGene:Hs.554531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057854 ! OR4A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019133 name: OR4A8P_human def: "Olfactory receptor 4A8 gene" [UniProtKB:P0C604] synonym: "OR4A8" EXACT [UniProtKB:P0C604] xref: EMBL:AC087377 xref: EMBL:AF546448 xref: EMBL:BK004702 xref: HGNC:HGNC:15165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054955 ! OR4A8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019134 name: OR4B1_human def: "Olfactory receptor 4B1 gene" [UniProtKB:Q8NGF8] xref: EMBL:AB065848 xref: EMBL:AF399579 xref: EMBL:BK004387 xref: HGNC:HGNC:8290 xref: UniGene:Hs.553566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057667 ! OR4B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019135 name: OR4C3_human def: "Olfactory receptor 4C3 gene" [UniProtKB:Q8NH37] xref: EMBL:AB065567 xref: EMBL:AC023080 xref: EMBL:BK004349 xref: HGNC:HGNC:14697 xref: UniGene:Hs.553656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054061 ! A8MVM5_HUMAN relationship: codes_for CCO:B0057820 ! OR4C3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019136 name: OR4C5_human def: "Olfactory receptor 4C5 gene" [UniProtKB:Q8NGB2] xref: EMBL:AB065910 xref: EMBL:BK004350 xref: HGNC:HGNC:14702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057639 ! OR4C5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019137 name: OR4C6_human def: "Olfactory receptor 4C6 gene" [UniProtKB:Q8NH72] xref: EMBL:AB065517 xref: EMBL:BK004330 xref: HGNC:HGNC:14743 xref: UniGene:Hs.511921 xref: UniGene:Hs.706616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057843 ! OR4C6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019138 name: OR4C11_human def: "Olfactory receptor 4C11 gene" [UniProtKB:Q6IEV9] synonym: "OR4C11P" EXACT [UniProtKB:Q6IEV9] xref: EMBL:AB065774 xref: EMBL:BK004503 xref: HGNC:HGNC:15167 xref: UniGene:Hs.553620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056764 ! OR4CB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019139 name: OR4C12_human def: "Olfactory receptor 4C12 gene" [UniProtKB:Q96R67] xref: EMBL:AF399576 xref: EMBL:AP006622 xref: EMBL:BK004413 xref: HGNC:HGNC:15168 xref: UniGene:Hs.553669 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053839 ! A6NH54_HUMAN relationship: codes_for CCO:B0058366 ! OR4CC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019140 name: OR4C13_human def: "Olfactory receptor 4C13 gene" [UniProtKB:Q8NGP0] xref: EMBL:AB065750 xref: EMBL:AF399575 xref: EMBL:AP006587 xref: EMBL:BK004414 xref: HGNC:HGNC:15169 xref: UniGene:Hs.553668 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057727 ! OR4CD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019141 name: OR4C15_human def: "Olfactory receptor 4C15 gene" [UniProtKB:Q8NGM1] xref: EMBL:AB065771 xref: EMBL:BK004319 xref: EMBL:BK004320 xref: HGNC:HGNC:15171 xref: UniGene:Hs.589003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057712 ! OR4CF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019142 name: OR4C16_human def: "Olfactory receptor 4C16 gene" [UniProtKB:Q8NGL9] xref: EMBL:AB065773 xref: EMBL:AP001998 xref: EMBL:BK004504 xref: HGNC:HGNC:15172 xref: UniGene:Hs.553619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057710 ! OR4CG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019143 name: OR4D1_human def: "Olfactory receptor 4D1 gene" [UniProtKB:Q15615] synonym: "OR4D3" EXACT [UniProtKB:Q15615] xref: EMBL:AB065913 xref: EMBL:AF399567 xref: EMBL:X89670 xref: HGNC:HGNC:8293 xref: UniGene:Hs.531188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056079 ! OR4D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019144 name: OR4D2_human def: "Olfactory receptor 4D2 gene" [UniProtKB:P58180] xref: EMBL:AB065912 xref: EMBL:AC005962 xref: EMBL:AF303373 xref: EMBL:AF399568 xref: EMBL:BK004224 xref: HGNC:HGNC:8294 xref: UniGene:Hs.446879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055566 ! OR4D2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019145 name: OR4D5_human def: "Olfactory receptor 4D5 gene" [UniProtKB:Q8NGN0] xref: EMBL:AB065760 xref: EMBL:BK004316 xref: HGNC:HGNC:14852 xref: UniGene:Hs.553639 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057718 ! OR4D5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019146 name: OR4D6_human def: "Olfactory receptor 4D6 gene" [UniProtKB:Q8NGJ1] xref: EMBL:AB065803 xref: EMBL:AF399569 xref: EMBL:BK004307 xref: HGNC:HGNC:15175 xref: UniGene:Hs.553650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057688 ! OR4D6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019147 name: OR4D9_human def: "Olfactory receptor 4D9 gene" [UniProtKB:Q8NGE8] xref: EMBL:AB065861 xref: EMBL:AC019093 xref: EMBL:BK004309 xref: HGNC:HGNC:15178 xref: UniGene:Hs.553757 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057663 ! OR4D9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019148 name: OR4D10_human def: "Olfactory receptor 4D10 gene" [UniProtKB:Q8NGI6] synonym: "OR4D10P" EXACT [UniProtKB:Q8NGI6] xref: EMBL:AB065808 xref: EMBL:BK004311 xref: HGNC:HGNC:15173 xref: UniGene:Hs.553756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057683 ! OR4DA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019149 name: OR4D11_human def: "Olfactory receptor 4D11 gene" [UniProtKB:Q8NGI4] synonym: "OR4D11P" EXACT [UniProtKB:Q8NGI4] xref: EMBL:AB065810 xref: HGNC:HGNC:15174 xref: UniGene:Hs.553651 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057681 ! OR4DB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019150 name: OR4E1_human def: "Olfactory receptor 4E1 gene" [UniProtKB:P0C645] synonym: "OR4E1P" EXACT [UniProtKB:P0C645] xref: EMBL:AB065562 xref: EMBL:AF399450 xref: EMBL:BK004671 xref: HGNC:HGNC:8296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054960 ! OR4E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019151 name: OR4E2_human def: "Olfactory receptor 4E2 gene" [UniProtKB:Q8NGC2] xref: EMBL:AB065895 xref: EMBL:AF399581 xref: EMBL:BK004526 xref: HGNC:HGNC:8297 xref: UniGene:Hs.547982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057645 ! OR4E2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019152 name: OR4F3_human def: "Olfactory receptor 4F3/4F16/4F29 gene" [UniProtKB:Q6IEY1] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056768 ! OR4F3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019153 name: OR4F16_human def: "Olfactory receptor 4F3/4F16/4F29 gene" [UniProtKB:Q6IEY1] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056768 ! OR4F3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019154 name: OR4F29_human def: "Olfactory receptor 4F3/4F16/4F29 gene" [UniProtKB:Q6IEY1] xref: EMBL:BC137568 xref: EMBL:BK004219 xref: HGNC:HGNC:31275 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056768 ! OR4F3_HUMAN relationship: codes_for CCO:B0056813 ! Q6IFP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019155 name: OR4F4_human def: "Olfactory receptor 4F4 gene" [UniProtKB:Q96R69] xref: EMBL:AF399574 xref: EMBL:BK004223 xref: EMBL:L78442 xref: HGNC:HGNC:8301 xref: UniGene:Hs.554420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058367 ! OR4F4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019156 name: OR4F5_human def: "Olfactory receptor 4F5 gene" [UniProtKB:Q8NH21] xref: EMBL:AB065592 xref: EMBL:AL627309 xref: HGNC:HGNC:14825 xref: UniGene:Hs.554500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057811 ! OR4F5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019157 name: OR4F6_human def: "Olfactory receptor 4F6 gene" [UniProtKB:Q8NGB9] synonym: "OR4F12" EXACT [UniProtKB:Q8NGB9] xref: EMBL:AB065899 xref: EMBL:BK004367 xref: HGNC:HGNC:15372 xref: UniGene:Hs.553399 xref: UniGene:Hs.578689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057644 ! OR4F6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019158 name: OR4K1_human def: "Olfactory receptor 4K1 gene" [UniProtKB:Q8NGD4] xref: EMBL:AB065881 xref: EMBL:AF399570 xref: HGNC:HGNC:14726 xref: UniGene:Hs.554584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057656 ! OR4K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019159 name: OR4K2_human def: "Olfactory receptor 4K2 gene" [UniProtKB:Q8NGD2] xref: EMBL:AB065883 xref: EMBL:BK004357 xref: HGNC:HGNC:14728 xref: UniGene:Hs.551345 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057654 ! OR4K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019160 name: OR4K3_human def: "Olfactory receptor 4K3 gene" [UniProtKB:Q96R72] synonym: "OR4K3P" EXACT [UniProtKB:Q96R72] xref: EMBL:AC024399 xref: EMBL:AF399571 xref: EMBL:BK004358 xref: HGNC:HGNC:14731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058368 ! OR4K3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019161 name: OR4K5_human def: "Olfactory receptor 4K5 gene" [UniProtKB:Q8NGD3] xref: EMBL:AB065882 xref: EMBL:BK004355 xref: HGNC:HGNC:14745 xref: UniGene:Hs.554585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057655 ! OR4K5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019162 name: OR4K13_human def: "Olfactory receptor 4K13 gene" [UniProtKB:Q8NH42] xref: EMBL:AB065559 xref: EMBL:BK004449 xref: HGNC:HGNC:15351 xref: UniGene:Hs.553573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057822 ! OR4KD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019163 name: OR4K14_human def: "Olfactory receptor 4K14 gene" [UniProtKB:Q8NGD5] xref: EMBL:AB065880 xref: EMBL:AF399572 xref: EMBL:BK004521 xref: HGNC:HGNC:15352 xref: UniGene:Hs.626814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057657 ! OR4KE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019164 name: OR4L1_human def: "Olfactory receptor 4L1 gene" [UniProtKB:Q8NH43] synonym: "OR4L2P" EXACT [UniProtKB:Q8NH43] xref: EMBL:AB065558 xref: EMBL:BK004467 xref: HGNC:HGNC:15356 xref: UniGene:Hs.553574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057823 ! OR4L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019165 name: OR4M1_human def: "Olfactory receptor 4M1 gene" [UniProtKB:Q8NGD0] xref: EMBL:AB065886 xref: HGNC:HGNC:14735 xref: UniGene:Hs.553829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057652 ! OR4M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019166 name: OR4M2_human def: "Olfactory receptor 4M2 gene" [UniProtKB:Q8NGB6] xref: EMBL:AB065903 xref: HGNC:HGNC:15373 xref: UniGene:Hs.701824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057642 ! OR4M2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019167 name: OR4N2_human def: "Olfactory receptor 4N2 gene" [UniProtKB:Q8NGD1] xref: EMBL:AB065885 xref: EMBL:BK004473 xref: HGNC:HGNC:14742 xref: UniGene:Hs.512490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057653 ! OR4N2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019168 name: OR4N4_human def: "Olfactory receptor 4N4 gene" [UniProtKB:Q8N0Y3] xref: EMBL:AB065653 xref: EMBL:AB065904 xref: EMBL:BK004406 xref: HGNC:HGNC:15375 xref: UniGene:Hs.704764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057417 ! OR4N4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019169 name: OR4N5_human def: "Olfactory receptor 4N5 gene" [UniProtKB:Q8IXE1] xref: EMBL:AB065890 xref: EMBL:BK004451 xref: HGNC:HGNC:15358 xref: UniGene:Hs.553766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057372 ! OR4N5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019170 name: OR4P4_human def: "Olfactory receptor 4P4 gene" [UniProtKB:Q8NGL7] synonym: "OR4P3P" EXACT [UniProtKB:Q8NGL7] xref: EMBL:AB065775 xref: HGNC:HGNC:15180 xref: UniGene:Hs.626750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057709 ! OR4P4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019171 name: OR4Q2_human def: "Olfactory receptor 4Q2 gene" [UniProtKB:P0C623] synonym: "OR4Q2P" EXACT [UniProtKB:P0C623] xref: EMBL:AF399446 xref: EMBL:AL359218 xref: EMBL:BK004624 xref: HGNC:HGNC:15359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053824 ! A6NFR0_HUMAN relationship: codes_for CCO:B0054957 ! OR4Q2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019172 name: OR4Q3_human def: "Olfactory receptor 4Q3 gene" [UniProtKB:Q8NH05] synonym: "C14orf13" EXACT [UniProtKB:Q8NH05] synonym: "OR4Q4" EXACT [UniProtKB:Q8NH05] xref: EMBL:AB065609 xref: EMBL:BK004488 xref: HGNC:HGNC:15426 xref: UniGene:Hs.553828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057801 ! OR4Q3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019173 name: OR4S1_human def: "Olfactory receptor 4S1 gene" [UniProtKB:Q8NGB4] xref: EMBL:AB065908 xref: EMBL:BK004348 xref: HGNC:HGNC:14705 xref: UniGene:Hs.553657 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057640 ! OR4S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019174 name: OR4S2_human def: "Olfactory receptor 4S2 gene" [UniProtKB:Q8NH73] synonym: "OR4S2P" EXACT [UniProtKB:Q8NH73] xref: EMBL:AB065516 xref: EMBL:BK004390 xref: HGNC:HGNC:15183 xref: UniGene:Hs.553621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057844 ! OR4S2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019175 name: OR4X1_human def: "Olfactory receptor 4X1 gene" [UniProtKB:Q8NH49] xref: EMBL:AB065544 xref: EMBL:BK004388 xref: HGNC:HGNC:14854 xref: UniGene:Hs.553742 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057826 ! OR4X1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019176 name: OR4X2_human def: "Olfactory receptor 4X2 gene" [UniProtKB:Q8NGF9] xref: EMBL:AB065847 xref: EMBL:AF399580 xref: EMBL:BK004389 xref: HGNC:HGNC:15184 xref: UniGene:Hs.553565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057668 ! OR4X2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019177 name: OR5A1_human def: "Olfactory receptor 5A1 gene" [UniProtKB:Q8NGJ0] synonym: "OR5A1P" EXACT [UniProtKB:Q8NGJ0] xref: EMBL:AB065804 xref: EMBL:AF399528 xref: HGNC:HGNC:8319 xref: UniGene:Hs.553649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057687 ! OR5A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019178 name: OR5A2_human def: "Olfactory receptor 5A2 gene" [UniProtKB:Q8NGI9] xref: EMBL:AB065805 xref: EMBL:AF399529 xref: HGNC:HGNC:15249 xref: UniGene:Hs.553648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057686 ! OR5A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019179 name: OR5B21_human def: "Olfactory receptor 5B21 gene" [UniProtKB:A6NL26] xref: EMBL:AP003557 xref: HGNC:HGNC:19616 xref: UniGene:Hs.553647 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053892 ! OR5BL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019180 name: OR5C1_human def: "Olfactory receptor 5C1 gene" [UniProtKB:Q8NGR4] synonym: "OR5C2P" EXACT [UniProtKB:Q8NGR4] xref: EMBL:AB065725 xref: EMBL:AF399514 xref: EMBL:BK004233 xref: EMBL:CH471090 xref: HGNC:HGNC:8331 xref: UniGene:Hs.534761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029030 ! OR5C1_HUMAN relationship: codes_for CCO:B0029036 ! Q6IFM9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019181 name: OR5D13_human def: "Olfactory receptor 5D13 gene" [UniProtKB:Q8NGL4] xref: EMBL:AB065778 xref: EMBL:BK004333 xref: EMBL:BK004394 xref: HGNC:HGNC:15280 xref: UniGene:Hs.553743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057706 ! OR5DD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019182 name: OR5D14_human def: "Olfactory receptor 5D14 gene" [UniProtKB:Q8NGL3] xref: EMBL:AB065779 xref: EMBL:AF399523 xref: EMBL:BK004393 xref: HGNC:HGNC:15281 xref: UniGene:Hs.553622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057705 ! OR5DE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019183 name: OR5D16_human def: "Olfactory receptor 5D16 gene" [UniProtKB:Q8NGK9] xref: EMBL:AB065783 xref: EMBL:AF399524 xref: EMBL:BK004397 xref: HGNC:HGNC:15283 xref: UniGene:Hs.554527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057703 ! OR5DG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019184 name: OR5D18_human def: "Olfactory receptor 5D18 gene" [UniProtKB:Q8NGL1] xref: EMBL:AB065781 xref: EMBL:AF399525 xref: EMBL:BC136925 xref: EMBL:BC136927 xref: EMBL:BK004329 xref: EMBL:BK004395 xref: EMBL:CH471076 xref: HGNC:HGNC:15285 xref: UniGene:Hs.553624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056787 ! Q6IFD3_HUMAN relationship: codes_for CCO:B0057704 ! OR5DI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019185 name: OR5F1_human def: "Olfactory receptor 5F1 gene" [UniProtKB:O95221] xref: EMBL:AF065863 xref: EMBL:AF399527 xref: EMBL:BK004343 xref: HGNC:HGNC:8343 xref: UniGene:Hs.553702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054736 ! OR5F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019186 name: OR5G3_human def: "Olfactory receptor 5G3 gene" [UniProtKB:P0C626] synonym: "OR5G3P" EXACT [UniProtKB:P0C626] synonym: "OR5G6P" EXACT [UniProtKB:P0C626] xref: EMBL:AB065498 xref: EMBL:BK004647 xref: HGNC:HGNC:15287 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054958 ! OR5G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019187 name: OR5M1_human def: "Olfactory receptor 5M1 gene" [UniProtKB:Q8NGP8] xref: EMBL:AB065742 xref: EMBL:AF399522 xref: EMBL:BK004402 xref: HGNC:HGNC:8352 xref: UniGene:Hs.553751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057734 ! OR5M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019188 name: OR5M3_human def: "Olfactory receptor 5M3 gene" [UniProtKB:Q8NGP4] xref: EMBL:AB065746 xref: EMBL:AF399518 xref: EMBL:BK004498 xref: HGNC:HGNC:14806 xref: UniGene:Hs.553631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057730 ! OR5M3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019189 name: OR5M8_human def: "Olfactory receptor 5M8 gene" [UniProtKB:Q8NGP6] xref: EMBL:AB065744 xref: EMBL:AF399520 xref: EMBL:BK004499 xref: HGNC:HGNC:14846 xref: UniGene:Hs.554522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057732 ! OR5M8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019190 name: OR5M9_human def: "Olfactory receptor 5M9 gene" [UniProtKB:Q8NGP3] xref: EMBL:AB065747 xref: EMBL:AF399519 xref: EMBL:BK004497 xref: HGNC:HGNC:15294 xref: UniGene:Hs.553749 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057729 ! OR5M9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019191 name: OR5M10_human def: "Olfactory receptor 5M10 gene" [UniProtKB:Q6IEU7] xref: EMBL:AP002517 xref: EMBL:BK004515 xref: HGNC:HGNC:15290 xref: UniGene:Hs.553750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056760 ! OR5MA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019192 name: OR5P2_human def: "Olfactory receptor 5P2 gene" [UniProtKB:Q8WZ92] xref: EMBL:AB065767 xref: EMBL:AF173006 xref: EMBL:BC101710 xref: EMBL:BC113557 xref: HGNC:HGNC:14783 xref: UniGene:Hs.351824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058053 ! OR5P2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019193 name: OR5P3_human def: "Olfactory receptor 5P3 gene" [UniProtKB:Q8WZ94] xref: EMBL:AB065770 xref: EMBL:AF158377 xref: HGNC:HGNC:14784 xref: UniGene:Hs.351825 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058054 ! OR5P3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019194 name: OR5V1_human def: "Olfactory receptor 5V1 gene" [UniProtKB:Q9UGF6] xref: EMBL:AJ459859 xref: EMBL:AL096770 xref: EMBL:AL662781 xref: EMBL:AL672167 xref: EMBL:AL732432 xref: EMBL:BC069149 xref: EMBL:BK004440 xref: EMBL:BX005133 xref: EMBL:CR759808 xref: HGNC:HGNC:13972 xref: UniGene:Hs.666316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053724 ! A2BDZ0_HUMAN relationship: codes_for CCO:B0054095 ! A8MXE9_HUMAN relationship: codes_for CCO:B0056859 ! Q6NTB5_HUMAN relationship: codes_for CCO:B0059121 ! OR5V1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019195 name: OR6A2_human def: "Olfactory receptor 6A2 gene" [UniProtKB:O95222] synonym: "OR6A1" EXACT [UniProtKB:O95222] synonym: "OR6A2P" EXACT [UniProtKB:O95222] xref: EMBL:AB065822 xref: EMBL:AF065870 xref: EMBL:AF321237 xref: EMBL:BC101489 xref: EMBL:BC101491 xref: EMBL:BK004427 xref: HGNC:HGNC:15301 xref: UniGene:Hs.652252 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054737 ! OR6A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019196 name: OR6B2_human def: "Olfactory receptor 6B2 gene" [UniProtKB:Q6IFH4] synonym: "OR6B2P" EXACT [UniProtKB:Q6IFH4] xref: EMBL:AB065663 xref: EMBL:BK004288 xref: HGNC:HGNC:15041 xref: UniGene:Hs.531343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056794 ! OR6B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019197 name: OR6B3_human def: "Olfactory receptor 6B3 gene" [UniProtKB:Q8NGW1] synonym: "OR6B3P" EXACT [UniProtKB:Q8NGW1] xref: EMBL:AB065662 xref: EMBL:BK004289 xref: HGNC:HGNC:15042 xref: UniGene:Hs.626616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057769 ! OR6B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019198 name: OR6C1_human def: "Olfactory receptor 6C1 gene" [UniProtKB:Q96RD1] xref: EMBL:AC122684 xref: EMBL:AF399506 xref: HGNC:HGNC:8355 xref: UniGene:Hs.553763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058372 ! OR6C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019199 name: OR6C2_human def: "Olfactory receptor 6C2 gene" [UniProtKB:Q9NZP2] xref: EMBL:AC122685 xref: EMBL:AF179766 xref: HGNC:HGNC:15436 xref: UniGene:Hs.524483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059008 ! OR6C2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019200 name: OR6C3_human def: "Olfactory receptor 6C3 gene" [UniProtKB:Q9NZP0] xref: EMBL:AC122684 xref: EMBL:AF179770 xref: HGNC:HGNC:15437 xref: UniGene:Hs.553653 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059007 ! OR6C3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019201 name: OR6C4_human def: "Olfactory receptor 6C4 gene" [UniProtKB:Q8NGE1] xref: EMBL:AB065869 xref: EMBL:AC009779 xref: HGNC:HGNC:19632 xref: UniGene:Hs.495021 xref: UniGene:Hs.554552 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054142 ! A8MZG7_HUMAN relationship: codes_for CCO:B0057659 ! OR6C4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019202 name: OR6C6_human def: "Olfactory receptor 6C6 gene" [UniProtKB:A6NF89] xref: EMBL:AC122684 xref: HGNC:HGNC:31293 xref: UniGene:Hs.554555 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053816 ! OR6C6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019203 name: OR6F1_human def: "Olfactory receptor 6F1 gene" [UniProtKB:Q8NGZ6] xref: EMBL:AB065619 xref: EMBL:AF399604 xref: EMBL:BK004460 xref: HGNC:HGNC:15027 xref: UniGene:Hs.591529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057794 ! OR6F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019204 name: OR6J1_human def: "Olfactory receptor 6J1 gene" [UniProtKB:Q8NGC5] synonym: "OR6J2" EXACT [UniProtKB:Q8NGC5] xref: EMBL:AB065892 xref: HGNC:HGNC:14707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057648 ! OR6J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019205 name: OR6K2_human def: "Olfactory receptor 6K2 gene" [UniProtKB:Q8NGY2] xref: EMBL:AB065634 xref: HGNC:HGNC:15029 xref: UniGene:Hs.554489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057783 ! OR6K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019206 name: OR6N1_human def: "Olfactory receptor 6N1 gene" [UniProtKB:Q8NGY5] xref: EMBL:AB065631 xref: EMBL:AF399608 xref: EMBL:AL513205 xref: HGNC:HGNC:15034 xref: UniGene:Hs.553592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057785 ! OR6N1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019207 name: OR6N2_human def: "Olfactory receptor 6N2 gene" [UniProtKB:Q8NGY6] xref: EMBL:AB065630 xref: HGNC:HGNC:15035 xref: UniGene:Hs.554487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057786 ! OR6N2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019208 name: OR6P1_human def: "Olfactory receptor 6P1 gene" [UniProtKB:Q8NGX9] xref: EMBL:AB065637 xref: EMBL:AL160283 xref: EMBL:BK004193 xref: HGNC:HGNC:15036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057780 ! OR6P1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019209 name: OR6Q1_human def: "Olfactory receptor 6Q1 gene" [UniProtKB:Q8NGQ2] xref: EMBL:AB065737 xref: EMBL:AF399609 xref: HGNC:HGNC:15302 xref: UniGene:Hs.690432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057735 ! OR6Q1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019210 name: OR6T1_human def: "Olfactory receptor 6T1 gene" [UniProtKB:Q8NGN1] xref: EMBL:AB065759 xref: HGNC:HGNC:14848 xref: UniGene:Hs.553638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057719 ! OR6T1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019211 name: OR6X1_human def: "Olfactory receptor 6X1 gene" [UniProtKB:Q8NH79] xref: EMBL:AB065510 xref: EMBL:AP000868 xref: EMBL:BK004362 xref: HGNC:HGNC:14737 xref: UniGene:Hs.553759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054086 ! A8MX01_HUMAN relationship: codes_for CCO:B0057850 ! OR6X1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019212 name: OR6Y1_human def: "Olfactory receptor 6Y1 gene" [UniProtKB:Q8NGX8] synonym: "OR6Y2" EXACT [UniProtKB:Q8NGX8] xref: EMBL:AB065638 xref: EMBL:AL365440 xref: EMBL:BK004192 xref: HGNC:HGNC:14823 xref: UniGene:Hs.553780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057779 ! OR6Y1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019213 name: OR7A2P_human def: "Putative olfactory receptor 7A2 gene" [UniProtKB:Q8NGA2] synonym: "OR7A2" EXACT [UniProtKB:Q8NGA2] synonym: "OR7A7" EXACT [UniProtKB:Q8NGA2] xref: EMBL:AB065924 xref: EMBL:AC005255 xref: EMBL:AF399544 xref: HGNC:HGNC:8370 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057631 ! OR7A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019214 name: OR7A5_human def: "Olfactory receptor 7A5 gene" [UniProtKB:Q15622] xref: EMBL:AC005255 xref: EMBL:AF399543 xref: EMBL:BC104809 xref: EMBL:BK004221 xref: EMBL:X89677 xref: EMBL:Y10530 xref: HGNC:HGNC:8368 xref: UniGene:Hs.137573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056082 ! OR7A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019215 name: OR7A10_human def: "Olfactory receptor 7A10 gene" [UniProtKB:O76100] xref: EMBL:AC005255 xref: EMBL:AF399542 xref: EMBL:BK004222 xref: HGNC:HGNC:8356 xref: UniGene:Hs.553776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054695 ! OR7AA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019216 name: OR7A17_human def: "Olfactory receptor 7A17 gene" [UniProtKB:O14581] xref: EMBL:AC002988 xref: EMBL:AF399541 xref: EMBL:BC101587 xref: EMBL:BC117357 xref: EMBL:BK004206 xref: HGNC:HGNC:8363 xref: UniGene:Hs.247717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054353 ! OR7AH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019217 name: OR7C1_human def: "Olfactory receptor 7C1 gene" [UniProtKB:O76099] synonym: "OR7C4" EXACT [UniProtKB:O76099] xref: EMBL:AC005255 xref: EMBL:AF399546 xref: EMBL:X89676 xref: HGNC:HGNC:8373 xref: UniGene:Hs.466053 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054694 ! OR7C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019218 name: OR7C2_human def: "Olfactory receptor 7C2 gene" [UniProtKB:O60412] synonym: "OR7C3" EXACT [UniProtKB:O60412] xref: EMBL:AC004659 xref: EMBL:AF399545 xref: EMBL:U86255 xref: HGNC:HGNC:8374 xref: UniGene:Hs.589620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054555 ! OR7C2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019219 name: OR7D2_human def: "Olfactory receptor 7D2 gene" [UniProtKB:Q96RA2] xref: EMBL:AB065928 xref: EMBL:AF399537 xref: EMBL:AK095468 xref: HGNC:HGNC:8378 xref: UniGene:Hs.531755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058370 ! OR7D2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019220 name: OR7D4_human def: "Olfactory receptor 7D4 gene" [UniProtKB:Q8NG98] synonym: "OR7D4P" EXACT [UniProtKB:Q8NG98] xref: EMBL:AB065929 xref: EMBL:BK004226 xref: HGNC:HGNC:8380 xref: UniGene:Hs.446910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057628 ! OR7D4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019221 name: OR7G1_human def: "Olfactory receptor 7G1 gene" [UniProtKB:Q8NGA0] synonym: "OR7G1P" EXACT [UniProtKB:Q8NGA0] xref: EMBL:AB065926 xref: EMBL:AF399538 xref: HGNC:HGNC:8465 xref: UniGene:Hs.553576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057629 ! OR7G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019222 name: OR7G3_human def: "Olfactory receptor 7G3 gene" [UniProtKB:Q8NG95] xref: EMBL:AB065932 xref: EMBL:AF399540 xref: HGNC:HGNC:8467 xref: UniGene:Hs.553775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057626 ! OR7G3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019223 name: OR8B2_human def: "Olfactory receptor 8B2 gene" [UniProtKB:Q96RD0] xref: EMBL:AB065826 xref: EMBL:AF399508 xref: EMBL:BK004500 xref: EMBL:CH471065 xref: HGNC:HGNC:8471 xref: UniGene:Hs.576944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057675 ! Q8NGH2_HUMAN relationship: codes_for CCO:B0058371 ! OR8B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019224 name: OR8B3_human def: "Olfactory receptor 8B3 gene" [UniProtKB:Q8NGG8] xref: EMBL:AB065827 xref: EMBL:AB065830 xref: HGNC:HGNC:8472 xref: UniGene:Hs.690456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057673 ! OR8B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019225 name: OR8B8_human def: "Olfactory receptor 8B8 gene" [UniProtKB:Q15620] xref: EMBL:AB065832 xref: EMBL:AF238488 xref: EMBL:AF399510 xref: EMBL:X89675 xref: HGNC:HGNC:8477 xref: UniGene:Hs.351822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056081 ! OR8B8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019226 name: OR8B12_human def: "Olfactory receptor 8B12 gene" [UniProtKB:Q8NGG6] xref: EMBL:AB065834 xref: EMBL:AF399511 xref: EMBL:BK004494 xref: HGNC:HGNC:15307 xref: UniGene:Hs.553634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057672 ! OR8BC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019227 name: OR8D1_human def: "Olfactory receptor 8D1 gene" [UniProtKB:Q8WZ84] synonym: "OR8D3" EXACT [UniProtKB:Q8WZ84] xref: EMBL:AF238489 xref: EMBL:BK004501 xref: HGNC:HGNC:8481 xref: UniGene:Hs.504211 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058052 ! OR8D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019228 name: OR8I2_human def: "Olfactory receptor 8I2 gene" [UniProtKB:Q8N0Y5] xref: EMBL:AB065656 xref: EMBL:AB065844 xref: EMBL:AF399513 xref: EMBL:BK004342 xref: HGNC:HGNC:15310 xref: UniGene:Hs.554524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057418 ! OR8I2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019229 name: OR8J1_human def: "Olfactory receptor 8J1 gene" [UniProtKB:Q8NGP2] xref: EMBL:AB065748 xref: EMBL:AF399515 xref: EMBL:BK004340 xref: HGNC:HGNC:14855 xref: UniGene:Hs.626841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057728 ! OR8J1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019230 name: OR8J2_human def: "Olfactory receptor 8J2 gene" [UniProtKB:Q8NGG1] synonym: "OR8J2P" EXACT [UniProtKB:Q8NGG1] xref: EMBL:AB065839 xref: EMBL:AC022882 xref: HGNC:HGNC:15311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057670 ! OR8J2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019231 name: OR8J3_human def: "Olfactory receptor 8J3 gene" [UniProtKB:Q8NGG0] xref: EMBL:AB065841 xref: EMBL:AF399516 xref: HGNC:HGNC:15312 xref: UniGene:Hs.554523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057669 ! OR8J3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019232 name: OR8K1_human def: "Olfactory receptor 8K1 gene" [UniProtKB:Q8NGG5] xref: EMBL:AB065835 xref: EMBL:AF399517 xref: EMBL:BK004339 xref: HGNC:HGNC:14831 xref: UniGene:Hs.553748 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057671 ! OR8K1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019233 name: OR8K3_human def: "Olfactory receptor 8K3 gene" [UniProtKB:Q8NH51] xref: EMBL:AB065541 xref: EMBL:BK004338 xref: HGNC:HGNC:15313 xref: UniGene:Hs.553629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057827 ! OR8K3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019234 name: OR8S1_human def: "Olfactory receptor 8S1 gene" [UniProtKB:Q8NH09] xref: EMBL:AB065604 xref: HGNC:HGNC:19628 xref: UniGene:Hs.524373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057805 ! OR8S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019235 name: OR9A2_human def: "Olfactory receptor 9A2 gene" [UniProtKB:Q8NGT5] xref: EMBL:AB065696 xref: EMBL:AB065874 xref: EMBL:BK004391 xref: HGNC:HGNC:15093 xref: UniGene:Hs.553594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057755 ! OR9A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019236 name: OR9A4_human def: "Olfactory receptor 9A4 gene" [UniProtKB:Q8NGU2] xref: EMBL:AB065689 xref: HGNC:HGNC:15095 xref: UniGene:Hs.690171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057760 ! OR9A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019237 name: OR9G1_human def: "Olfactory receptor 9G1 gene" [UniProtKB:Q8NH87] synonym: "OR9G5" EXACT [UniProtKB:Q8NH87] xref: EMBL:AB065500 xref: EMBL:AB065739 xref: EMBL:BK004513 xref: HGNC:HGNC:15319 xref: UniGene:Hs.553752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057857 ! OR9G1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019238 name: OR9G9_human def: "Olfactory receptor 9G9 gene" [UniProtKB:P0C7N8] xref: EMBL:CH471076 xref: HGNC:HGNC:31940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054964 ! OR9G9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019239 name: OR9Q1_human def: "Olfactory receptor 9Q1 gene" [UniProtKB:Q8NGQ5] xref: EMBL:AB065734 xref: EMBL:AF399532 xref: EMBL:BC110819 xref: HGNC:HGNC:14724 xref: UniGene:Hs.689841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057737 ! OR9Q1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019240 name: HCRT_human def: "Orexin precursor gene" [UniProtKB:O43612] synonym: "OX" EXACT [UniProtKB:O43612] synonym: "PPORX" EXACT [UniProtKB:O43612] synonym: "PPOX" EXACT [UniProtKB:O43612] xref: EMBL:AF041240 xref: EMBL:AF118885 xref: HGNC:HGNC:4847 xref: UniGene:Hs.158348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054501 ! OREX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019241 name: OSMR_human def: "Oncostatin-M specific receptor subunit beta precursor gene" [UniProtKB:Q99650] synonym: "OSMRB" EXACT [UniProtKB:Q99650] xref: EMBL:BC010943 xref: EMBL:BC063468 xref: EMBL:BC125209 xref: EMBL:BC125210 xref: EMBL:U60805 xref: HGNC:HGNC:8507 xref: UniGene:Hs.120658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058434 ! OSMR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019242 name: OSR2_human def: "Protein odd-skipped-related 2 gene" [UniProtKB:Q8N2R0] xref: EMBL:AK074518 xref: EMBL:AY038072 xref: EMBL:AY038073 xref: EMBL:BC016936 xref: HGNC:HGNC:15830 xref: UniGene:Hs.253247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057447 ! OSR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019243 name: BGLAP_human def: "Osteocalcin precursor gene" [UniProtKB:P02818] xref: EMBL:AL135927 xref: EMBL:BC113432 xref: EMBL:BC113434 xref: EMBL:CH471121 xref: EMBL:DQ007079 xref: EMBL:X04143 xref: EMBL:X51699 xref: EMBL:X53698 xref: HGNC:HGNC:1043 xref: UniGene:Hs.654541 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054878 ! OSTC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019244 name: OSTF1_human def: "Osteoclast-stimulating factor 1 gene" [UniProtKB:Q92882] xref: EMBL:AK222596 xref: EMBL:AL133548 xref: EMBL:BC007459 xref: EMBL:U63717 xref: HGNC:HGNC:8510 xref: UniGene:Hs.494192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058109 ! OSTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019245 name: OSTN_human def: "Osteocrin precursor gene" [UniProtKB:P61366] xref: EMBL:AY398681 xref: EMBL:AY573933 xref: HGNC:HGNC:29961 xref: UniGene:Hs.526794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055609 ! OSTN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019246 name: OTP_human def: "Homeobox protein orthopedia gene" [UniProtKB:Q5XKR4] xref: EMBL:BC001800 xref: HGNC:HGNC:8518 xref: UniGene:Hs.202247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056683 ! OTP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019247 name: OTUD7B_human def: "OTU domain-containing protein 7B gene" [UniProtKB:Q6GQQ9] synonym: "ZA20D1" EXACT [UniProtKB:Q6GQQ9] xref: EMBL:AJ293573 xref: EMBL:AL122102 xref: EMBL:BC020622 xref: EMBL:BC072681 xref: HGNC:HGNC:16683 xref: UniGene:Hs.98322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056735 ! OTU7B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019248 name: OTX1_human def: "Homeobox protein OTX1 gene" [UniProtKB:P32242] xref: EMBL:AC009501 xref: EMBL:BC007621 xref: HGNC:HGNC:8521 xref: UniGene:Hs.445340 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055254 ! OTX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019249 name: OTX2_human def: "Homeobox protein OTX2 gene" [UniProtKB:P32243] xref: EMBL:AB037505 xref: EMBL:AF093138 xref: EMBL:AF298117 xref: EMBL:BC032579 xref: HGNC:HGNC:8522 xref: UniGene:Hs.288655 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055255 ! OTX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019250 name: HCRTR1_human def: "Orexin receptor type 1 gene" [UniProtKB:O43613] xref: EMBL:AC114488 xref: EMBL:AF041243 xref: EMBL:AF202078 xref: EMBL:AF202079 xref: EMBL:AF202080 xref: EMBL:AF202081 xref: EMBL:AF202082 xref: EMBL:AF202083 xref: EMBL:AF202084 xref: EMBL:AY062030 xref: EMBL:AY070269 xref: EMBL:BC074796 xref: EMBL:CH471059 xref: HGNC:HGNC:4848 xref: UniGene:Hs.388226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053909 ! A6NMV7_HUMAN relationship: codes_for CCO:B0054502 ! OX1R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019251 name: QRFP_human def: "Orexigenic neuropeptide QRFP precursor gene" [UniProtKB:P83859] xref: EMBL:AB109625 xref: EMBL:AL161733 xref: EMBL:AY438326 xref: EMBL:BC101127 xref: HGNC:HGNC:29982 xref: UniGene:Hs.660704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055661 ! OX26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019252 name: HCRTR2_human def: "Orexin receptor type 2 gene" [UniProtKB:O43614] xref: EMBL:AF041245 xref: EMBL:AL449104 xref: EMBL:AL591718 xref: EMBL:AY062031 xref: EMBL:CH471081 xref: HGNC:HGNC:4849 xref: UniGene:Hs.151624 xref: UniGene:Hs.699147 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054503 ! OX2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019253 name: OXER1_human def: "Oxoeicosanoid receptor 1 gene" [UniProtKB:Q8TDS5] synonym: "GPR170" EXACT [UniProtKB:Q8TDS5] synonym: "TG1019" EXACT [UniProtKB:Q8TDS5] xref: EMBL:AB065652 xref: EMBL:AB083055 xref: EMBL:AB083630 xref: EMBL:AC098824 xref: EMBL:AY158687 xref: EMBL:BC063549 xref: HGNC:HGNC:24884 xref: UniGene:Hs.168439 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057933 ! OXER1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019254 name: OXGR1_human def: "2-oxoglutarate receptor 1 gene" [UniProtKB:Q96P68] synonym: "GPR80" EXACT [UniProtKB:Q96P68] synonym: "GPR99" EXACT [UniProtKB:Q96P68] synonym: "P2RY15" EXACT [UniProtKB:Q96P68] synonym: "P2Y15" EXACT [UniProtKB:Q96P68] xref: EMBL:AB065877 xref: EMBL:AB083598 xref: EMBL:AF370886 xref: EMBL:AF411109 xref: EMBL:AJ305372 xref: EMBL:AL356486 xref: EMBL:BC103881 xref: EMBL:BC103882 xref: EMBL:BC103883 xref: HGNC:HGNC:4531 xref: UniGene:Hs.352218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058323 ! OXGR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019255 name: OXSR1_human def: "Serine/threonine-protein kinase OSR1 gene" [UniProtKB:O95747] synonym: "KIAA1101" EXACT [UniProtKB:O95747] synonym: "OSR1" EXACT [UniProtKB:O95747] xref: EMBL:AB017642 xref: EMBL:AB029024 xref: EMBL:AF087893 xref: EMBL:BC008726 xref: EMBL:DQ201638 xref: HGNC:HGNC:8508 xref: UniGene:Hs.475970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054791 ! OXSR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019256 name: OXTR_human def: "Oxytocin receptor gene" [UniProtKB:P30559] xref: EMBL:AY389507 xref: EMBL:X64878 xref: EMBL:X80282 xref: HGNC:HGNC:8529 xref: UniGene:Hs.2820 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055224 ! OXYR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019257 name: ZNF146_human def: "Zinc finger protein OZF gene" [UniProtKB:Q15072] synonym: "OZF" EXACT [UniProtKB:Q15072] xref: EMBL:AC012617 xref: EMBL:AJ011806 xref: EMBL:BC110500 xref: EMBL:BC110501 xref: EMBL:X70394 xref: HGNC:HGNC:12931 xref: UniGene:Hs.643436 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056041 ! OZF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019258 name: P2RX1_human def: "P2X purinoceptor 1 gene" [UniProtKB:P51575] synonym: "P2X1" EXACT [UniProtKB:P51575] xref: EMBL:AF020498 xref: EMBL:AF177472 xref: EMBL:BC044657 xref: EMBL:U45448 xref: EMBL:X83688 xref: HGNC:HGNC:8533 xref: UniGene:Hs.41735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055468 ! P2RX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019259 name: P2RX2_human def: "P2X purinoceptor 2 gene" [UniProtKB:Q9UBL9] synonym: "P2X2" EXACT [UniProtKB:Q9UBL9] xref: EMBL:AC131212 xref: EMBL:AF109387 xref: EMBL:AF109388 xref: EMBL:AF190822 xref: EMBL:AF190823 xref: EMBL:AF190824 xref: EMBL:AF190825 xref: EMBL:AF190826 xref: EMBL:AF260426 xref: EMBL:AF260427 xref: EMBL:AF260428 xref: EMBL:AF260429 xref: EMBL:AY346374 xref: HGNC:HGNC:15459 xref: UniGene:Hs.258580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059076 ! P2RX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019260 name: P2RX3_human def: "P2X purinoceptor 3 gene" [UniProtKB:P56373] xref: EMBL:AB016608 xref: EMBL:Y07683 xref: HGNC:HGNC:8534 xref: UniGene:Hs.146738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055544 ! P2RX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019261 name: P2RX4_human def: "P2X purinoceptor 4 gene" [UniProtKB:Q99571] xref: EMBL:AF000234 xref: EMBL:AF012903 xref: EMBL:AF191093 xref: EMBL:U83993 xref: EMBL:U85971 xref: EMBL:U85972 xref: EMBL:U85973 xref: EMBL:U85974 xref: EMBL:U85975 xref: EMBL:U87270 xref: EMBL:Y07684 xref: HGNC:HGNC:8535 xref: UniGene:Hs.321709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058423 ! P2RX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019262 name: P2RX5_human def: "P2X purinoceptor 5 gene" [UniProtKB:Q93086] synonym: "P2X5" EXACT [UniProtKB:Q93086] xref: EMBL:AB209623 xref: EMBL:AF016709 xref: EMBL:AF070573 xref: EMBL:AF168787 xref: EMBL:AK290889 xref: EMBL:AK307959 xref: EMBL:BC028084 xref: EMBL:BC039015 xref: EMBL:U49395 xref: EMBL:U49396 xref: HGNC:HGNC:8536 xref: UniGene:Hs.408615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058122 ! P2RX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019263 name: P2RX6_human def: "P2X purinoceptor 6 gene" [UniProtKB:O15547] synonym: "P2RXL1" EXACT [UniProtKB:O15547] synonym: "P2X6" EXACT [UniProtKB:O15547] xref: EMBL:AB002058 xref: EMBL:AB002059 xref: EMBL:AF065385 xref: EMBL:BC033488 xref: EMBL:CR456535 xref: HGNC:HGNC:8538 xref: UniGene:Hs.113275 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054447 ! P2RX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019264 name: P2RX7_human def: "P2X purinoceptor 7 gene" [UniProtKB:Q99572] xref: EMBL:BC011913 xref: EMBL:Y09561 xref: EMBL:Y12851 xref: EMBL:Y12852 xref: EMBL:Y12853 xref: EMBL:Y12854 xref: EMBL:Y12855 xref: EMBL:Z98941 xref: HGNC:HGNC:8537 xref: UniGene:Hs.507102 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058424 ! P2RX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019265 name: P2RY1_human def: "P2Y purinoceptor 1 gene" [UniProtKB:P47900] xref: EMBL:AF018284 xref: EMBL:AJ006945 xref: EMBL:AY136752 xref: EMBL:BC074784 xref: EMBL:BC074785 xref: EMBL:S81950 xref: EMBL:U42029 xref: EMBL:U42030 xref: EMBL:Z49205 xref: HGNC:HGNC:8539 xref: UniGene:Hs.654526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055394 ! P2RY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019266 name: P2RY2_human def: "P2Y purinoceptor 2 gene" [UniProtKB:P41231] synonym: "P2RU1" EXACT [UniProtKB:P41231] xref: EMBL:AY136753 xref: EMBL:BC012104 xref: EMBL:BC028135 xref: EMBL:U07225 xref: HGNC:HGNC:8541 xref: UniGene:Hs.339 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055338 ! P2RY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019267 name: P2RY4_human def: "P2Y purinoceptor 4 gene" [UniProtKB:P51582] synonym: "NRU" EXACT [UniProtKB:P51582] xref: EMBL:AL357752 xref: EMBL:BC095503 xref: EMBL:BC096067 xref: EMBL:BC096068 xref: EMBL:BC096069 xref: EMBL:BC096070 xref: EMBL:U40223 xref: EMBL:X91852 xref: EMBL:X96597 xref: HGNC:HGNC:8542 xref: UniGene:Hs.673854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055469 ! P2RY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019268 name: P2RY5_human def: "Oleoyl-L-alpha-lysophosphatidic acid receptor gene" [UniProtKB:P43657] xref: EMBL:AF000546 xref: EMBL:AF551763 xref: EMBL:AK223389 xref: EMBL:AL392048 xref: EMBL:BC040850 xref: EMBL:BC045651 xref: EMBL:BC070295 xref: EMBL:BC106756 xref: EMBL:BX537392 xref: EMBL:BX537438 xref: EMBL:BX537445 xref: EMBL:CH471075 xref: EMBL:L11910 xref: EMBL:L78805 xref: HGNC:HGNC:15520 xref: UniGene:Hs.123464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055367 ! P2RY5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019269 name: P2RY6_human def: "P2Y purinoceptor 6 gene" [UniProtKB:Q15077] synonym: "PP2891" EXACT [UniProtKB:Q15077] xref: EMBL:AF007891 xref: EMBL:AF007892 xref: EMBL:AF218005 xref: EMBL:AF498920 xref: EMBL:BC000571 xref: EMBL:BC009391 xref: EMBL:BT006771 xref: EMBL:U52464 xref: EMBL:X97058 xref: HGNC:HGNC:8543 xref: UniGene:Hs.16362 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056042 ! P2RY6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019270 name: P2RY10_human def: "Putative P2Y purinoceptor 10 gene" [UniProtKB:O00398] xref: EMBL:AF000545 xref: EMBL:AY275461 xref: EMBL:BC051875 xref: EMBL:BC095498 xref: EMBL:Z82200 xref: HGNC:HGNC:19906 xref: UniGene:Hs.296433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054316 ! P2Y10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019271 name: P2RY11_human def: "P2Y purinoceptor 11 gene" [UniProtKB:Q96G91] xref: EMBL:AF030335 xref: EMBL:AF498921 xref: EMBL:AJ298334 xref: EMBL:AJ300588 xref: EMBL:AY449733 xref: EMBL:BC073827 xref: HGNC:HGNC:8540 xref: UniGene:Hs.14468 xref: UniGene:Hs.655318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058213 ! P2Y11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019272 name: P2RY12_human def: "P2Y purinoceptor 12 gene" [UniProtKB:Q9H244] synonym: "HORK3" EXACT [UniProtKB:Q9H244] xref: EMBL:AB052684 xref: EMBL:AB083596 xref: EMBL:AF310685 xref: EMBL:AF313449 xref: EMBL:AF321815 xref: EMBL:AJ320495 xref: EMBL:AY136754 xref: EMBL:BC017898 xref: HGNC:HGNC:18124 xref: UniGene:Hs.591281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058675 ! P2Y12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019273 name: P2RY13_human def: "P2Y purinoceptor 13 gene" [UniProtKB:Q9BPV8] synonym: "FKSG77" EXACT [UniProtKB:Q9BPV8] synonym: "GPR86" EXACT [UniProtKB:Q9BPV8] synonym: "GPR94" EXACT [UniProtKB:Q9BPV8] xref: EMBL:AB083597 xref: EMBL:AF295368 xref: EMBL:AF345565 xref: EMBL:AF406692 xref: EMBL:AF411113 xref: EMBL:BC029363 xref: EMBL:BC041116 xref: HGNC:HGNC:4537 xref: UniGene:Hs.546396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055756 ! Q05C50_HUMAN relationship: codes_for CCO:B0058469 ! P2Y13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019274 name: P2RY14_human def: "P2Y purinoceptor 14 gene" [UniProtKB:Q15391] synonym: "GPR105" EXACT [UniProtKB:Q15391] synonym: "KIAA0001" EXACT [UniProtKB:Q15391] xref: EMBL:AF456925 xref: EMBL:BC034989 xref: EMBL:D13626 xref: HGNC:HGNC:16442 xref: UniGene:Hs.2465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056060 ! P2Y14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019275 name: PIK3C2G_human def: "Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide gene" [UniProtKB:O75747] xref: EMBL:AJ000008 xref: HGNC:HGNC:8973 xref: UniGene:Hs.22500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054663 ! P3C2G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019276 name: LEPRE1_human def: "Prolyl 3-hydroxylase 1 precursor gene" [UniProtKB:Q32P28] synonym: "GROS1" EXACT [UniProtKB:Q32P28] synonym: "P3H1" EXACT [UniProtKB:Q32P28] synonym: "PSEC0109" EXACT [UniProtKB:Q32P28] xref: EMBL:AF097431 xref: EMBL:AF097432 xref: EMBL:AK025841 xref: EMBL:AK027648 xref: EMBL:AK027680 xref: EMBL:AK027697 xref: EMBL:AK075418 xref: EMBL:BC015309 xref: EMBL:BC108311 xref: EMBL:BT007039 xref: HGNC:HGNC:19316 xref: UniGene:Hs.437656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056240 ! P3H1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019277 name: PRKRIR_human def: "52 kDa repressor of the inhibitor of the protein kinase gene" [UniProtKB:O43422] synonym: "DAP4" EXACT [UniProtKB:O43422] synonym: "P52RIPK" EXACT [UniProtKB:O43422] synonym: "THAP0" EXACT [UniProtKB:O43422] xref: EMBL:AF007393 xref: EMBL:AF081567 xref: EMBL:AL049970 xref: EMBL:BC021992 xref: EMBL:BC117138 xref: EMBL:BC117140 xref: HGNC:HGNC:9440 xref: UniGene:Hs.503315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054480 ! P52K_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019278 name: PIK3R3_human def: "Phosphatidylinositol 3-kinase regulatory subunit gamma gene" [UniProtKB:Q92569] xref: EMBL:AF028785 xref: EMBL:AL358075 xref: EMBL:BC021622 xref: EMBL:D88532 xref: HGNC:HGNC:8981 xref: UniGene:Hs.655387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026600 ! P55G_HUMAN relationship: codes_for CCO:B0026605 ! Q8N381_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019279 name: TP53I11_human def: "Tumor protein p53-inducible protein 11 gene" [UniProtKB:O14683] synonym: "PIG11" EXACT [UniProtKB:O14683] xref: EMBL:AF010315 xref: HGNC:HGNC:16842 xref: UniGene:Hs.554791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054366 ! P5I11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019280 name: PIK3R1_human def: "Phosphatidylinositol 3-kinase regulatory subunit alpha gene" [UniProtKB:P27986] synonym: "GRB1" EXACT [UniProtKB:P27986] xref: EMBL:AF279367 xref: EMBL:AK223613 xref: EMBL:BC030815 xref: EMBL:BC094795 xref: EMBL:M61906 xref: EMBL:U49349 xref: HGNC:HGNC:8979 xref: UniGene:Hs.132225 xref: UniGene:Hs.604502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026608 ! P85A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019281 name: PIK3R2_human def: "Phosphatidylinositol 3-kinase regulatory subunit beta gene" [UniProtKB:O00459] xref: EMBL:AC007192 xref: EMBL:BC032647 xref: EMBL:BC070082 xref: EMBL:BC090249 xref: EMBL:X80907 xref: HGNC:HGNC:8980 xref: UniGene:Hs.371344 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026602 ! P85B_HUMAN relationship: codes_for CCO:B0026606 ! Q05BV6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019282 name: PLA2G1B_human def: "Phospholipase A2 precursor gene" [UniProtKB:P04054] synonym: "PLA2" EXACT [UniProtKB:P04054] synonym: "PLA2A" EXACT [UniProtKB:P04054] synonym: "PPLA2" EXACT [UniProtKB:P04054] xref: EMBL:AC003982 xref: EMBL:AK311830 xref: EMBL:AY438977 xref: EMBL:BC106725 xref: EMBL:BC106726 xref: EMBL:CH471054 xref: EMBL:M21054 xref: EMBL:M21056 xref: EMBL:M22970 xref: HGNC:HGNC:9030 xref: UniGene:Hs.992 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054883 ! PA21B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019283 name: PLA2G4B_human def: "Cytosolic phospholipase A2 beta gene" [UniProtKB:P0C869] xref: EMBL:AB209150 xref: EMBL:AC020659 xref: EMBL:AF065215 xref: EMBL:AF121908 xref: HGNC:HGNC:9036 xref: UniGene:Hs.198161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016489 ! PA24B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019284 name: PLA2G4C_human def: "Cytosolic phospholipase A2 gamma precursor gene" [UniProtKB:Q9UP65] xref: EMBL:AB105807 xref: EMBL:AF058921 xref: EMBL:AF065214 xref: EMBL:AL050193 xref: EMBL:AY485310 xref: EMBL:BC063416 xref: HGNC:HGNC:9037 xref: UniGene:Hs.631562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059258 ! PA24C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019285 name: PACSIN3_human def: "Protein kinase C and casein kinase substrate in neurons protein 3 gene" [UniProtKB:Q9UKS6] xref: EMBL:AC090589 xref: EMBL:AF130979 xref: EMBL:AF149825 xref: EMBL:AF242530 xref: EMBL:AK000577 xref: EMBL:BC007914 xref: EMBL:BC011889 xref: HGNC:HGNC:8572 xref: UniGene:Hs.334639 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059200 ! PACN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019286 name: ADCYAP1R1_human def: "Pituitary adenylate cyclase-activating polypeptide type I receptor precursor gene" [UniProtKB:P41586] xref: EMBL:AB065700 xref: EMBL:AY366498 xref: EMBL:AY462278 xref: EMBL:AY495951 xref: EMBL:BC117116 xref: EMBL:D17516 xref: EMBL:U09216 xref: HGNC:HGNC:242 xref: UniGene:Hs.377783 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055341 ! PACR_HUMAN relationship: codes_for CCO:B0056189 ! Q17S10_HUMAN relationship: codes_for CCO:B0056936 ! Q6RKA3_HUMAN relationship: codes_for CCO:B0056939 ! Q6S992_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019287 name: PADI4_human def: "Protein-arginine deiminase type-4 gene" [UniProtKB:Q9UM07] synonym: "PADI5" EXACT [UniProtKB:Q9UM07] synonym: "PDI5" EXACT [UniProtKB:Q9UM07] xref: EMBL:AB017919 xref: EMBL:AC004824 xref: EMBL:AJ549502 xref: EMBL:AL590644 xref: EMBL:BC025718 xref: HGNC:HGNC:18368 xref: UniGene:Hs.522969 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028677 ! PADI4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019288 name: PAF1_human def: "RNA polymerase II-associated factor 1 homolog gene" [UniProtKB:Q8N7H5] synonym: "PD2" EXACT [UniProtKB:Q8N7H5] xref: EMBL:AC005239 xref: EMBL:AJ401156 xref: EMBL:AK001985 xref: EMBL:AK098423 xref: EMBL:BC000017 xref: EMBL:BC013402 xref: EMBL:CH471126 xref: HGNC:HGNC:25459 xref: UniGene:Hs.466714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057502 ! PAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019289 name: PAG1_human def: "Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 gene" [UniProtKB:Q9NWQ8] synonym: "CBP" EXACT [UniProtKB:Q9NWQ8] synonym: "PAG" EXACT [UniProtKB:Q9NWQ8] xref: EMBL:AF240634 xref: EMBL:AK000680 xref: EMBL:BC090931 xref: EMBL:BC112159 xref: HGNC:HGNC:30043 xref: UniGene:Hs.266175 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058939 ! PAG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019290 name: PAIP2B_human def: "Polyadenylate-binding protein-interacting protein 2B gene" [UniProtKB:Q9ULR5] synonym: "KIAA1155" EXACT [UniProtKB:Q9ULR5] xref: EMBL:AB032981 xref: HGNC:HGNC:29200 xref: UniGene:Hs.416735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059232 ! PAI2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019291 name: SERPINB2_human def: "Plasminogen activator inhibitor 2 precursor gene" [UniProtKB:P05120] synonym: "PAI2" EXACT [UniProtKB:P05120] synonym: "PLANH2" EXACT [UniProtKB:P05120] xref: EMBL:BC012609 xref: EMBL:J02685 xref: EMBL:J03603 xref: EMBL:M18082 xref: EMBL:M24651 xref: EMBL:M24652 xref: EMBL:M24653 xref: EMBL:M24654 xref: EMBL:M24655 xref: EMBL:M24656 xref: EMBL:M24657 xref: EMBL:M31547 xref: EMBL:M31548 xref: EMBL:M31549 xref: EMBL:M31550 xref: EMBL:M31551 xref: EMBL:Y00630 xref: HGNC:HGNC:8584 xref: UniGene:Hs.594481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054896 ! PAI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019292 name: PAIP1_human def: "Polyadenylate-binding protein-interacting protein 1 gene" [UniProtKB:Q9H074] xref: EMBL:AF013758 xref: EMBL:AL136920 xref: EMBL:BC005295 xref: EMBL:BC015937 xref: HGNC:HGNC:16945 xref: UniGene:Hs.482038 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058648 ! PAIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019293 name: PAIP2_human def: "Polyadenylate-binding protein-interacting protein 2 gene" [UniProtKB:Q9BPZ3] synonym: "HSPC218" EXACT [UniProtKB:Q9BPZ3] synonym: "PAIP2A" EXACT [UniProtKB:Q9BPZ3] xref: EMBL:AF151052 xref: EMBL:AF317675 xref: EMBL:AL136640 xref: EMBL:BC001716 xref: EMBL:BC048106 xref: EMBL:BC062718 xref: HGNC:HGNC:17970 xref: UniGene:Hs.396644 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058473 ! PAIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019294 name: PAK4_human def: "Serine/threonine-protein kinase PAK 4 gene" [UniProtKB:O96013] synonym: "KIAA1142" EXACT [UniProtKB:O96013] xref: EMBL:AB032968 xref: EMBL:AF005046 xref: EMBL:AJ011855 xref: EMBL:AK074728 xref: EMBL:AL834236 xref: EMBL:BC002921 xref: EMBL:BC011368 xref: EMBL:BC025282 xref: EMBL:BC034511 xref: HGNC:HGNC:16059 xref: UniGene:Hs.20447 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054821 ! PAK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019295 name: PALM2_human def: "Paralemmin-2 gene" [UniProtKB:Q8IXS6] xref: EMBL:AJ312216 xref: EMBL:AK095003 xref: EMBL:AL135789 xref: EMBL:AL158829 xref: EMBL:AL353806 xref: EMBL:AL627225 xref: EMBL:BC039306 xref: HGNC:HGNC:15845 xref: UniGene:Hs.591908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057380 ! PALM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019296 name: PALMD_human def: "Palmdelphin gene" [UniProtKB:Q9NP74] synonym: "C1orf11" EXACT [UniProtKB:Q9NP74] synonym: "PALML" EXACT [UniProtKB:Q9NP74] xref: EMBL:AF262379 xref: EMBL:AJ312214 xref: EMBL:AK000278 xref: EMBL:AK024654 xref: EMBL:AL390970 xref: EMBL:AL390971 xref: EMBL:AL390972 xref: EMBL:AL390973 xref: EMBL:BC012570 xref: HGNC:HGNC:15846 xref: UniGene:Hs.483993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058837 ! PALMD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019297 name: PALM_human def: "Paralemmin gene" [UniProtKB:O75781] synonym: "KIAA0270" EXACT [UniProtKB:O75781] xref: EMBL:AC004030 xref: EMBL:AC005763 xref: EMBL:BC032449 xref: EMBL:D87460 xref: EMBL:Y14770 xref: EMBL:Y16270 xref: EMBL:Y16271 xref: EMBL:Y16272 xref: EMBL:Y16273 xref: EMBL:Y16274 xref: EMBL:Y16275 xref: EMBL:Y16276 xref: EMBL:Y16277 xref: EMBL:Y16278 xref: HGNC:HGNC:8594 xref: UniGene:Hs.631841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054665 ! PALM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019298 name: PAPPA2_human def: "Pappalysin-2 precursor gene" [UniProtKB:Q9BXP8] synonym: "PLAC3" EXACT [UniProtKB:Q9BXP8] xref: EMBL:AF311940 xref: EMBL:AF342989 xref: EMBL:AF342990 xref: EMBL:AJ278348 xref: EMBL:AL031290 xref: EMBL:AL031734 xref: EMBL:AL139282 xref: EMBL:AL596254 xref: HGNC:HGNC:14615 xref: UniGene:Hs.187284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058562 ! PAPP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019299 name: PARP14_human def: "Poly [ADP-ribose] polymerase 14 gene" [UniProtKB:Q460N5] synonym: "BAL2" EXACT [UniProtKB:Q460N5] synonym: "KIAA1268" EXACT [UniProtKB:Q460N5] xref: EMBL:AB033094 xref: EMBL:AK001770 xref: EMBL:AK022542 xref: EMBL:AY134858 xref: EMBL:DB237115 xref: EMBL:DQ063584 xref: EMBL:DQ063585 xref: HGNC:HGNC:29232 xref: UniGene:Hs.518203 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056288 ! PAR14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019300 name: PARP15_human def: "Poly [ADP-ribose] polymerase 15 gene" [UniProtKB:Q460N3] synonym: "BAL3" EXACT [UniProtKB:Q460N3] xref: EMBL:AK097916 xref: EMBL:BC101701 xref: EMBL:BC101703 xref: EMBL:DQ063586 xref: HGNC:HGNC:26876 xref: UniGene:Hs.120250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056287 ! PAR15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019301 name: PARF_human def: "Putative GTP-binding protein Parf gene" [UniProtKB:Q3YEC7] synonym: "C9orf86" EXACT [UniProtKB:Q3YEC7] xref: EMBL:AK023107 xref: EMBL:AK027586 xref: EMBL:AL355987 xref: EMBL:AL713707 xref: EMBL:BC002945 xref: EMBL:BC021095 xref: EMBL:BC035786 xref: EMBL:DQ099383 xref: EMBL:DQ141240 xref: HGNC:HGNC:24703 xref: UniGene:Hs.567803 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056279 ! PARF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019302 name: PASK_human def: "PAS domain-containing serine/threonine-protein kinase gene" [UniProtKB:Q96RG2] synonym: "KIAA0135" EXACT [UniProtKB:Q96RG2] xref: EMBL:AF387103 xref: EMBL:BC043495 xref: EMBL:BC050565 xref: EMBL:BC063585 xref: EMBL:CR749231 xref: EMBL:D50925 xref: EMBL:U79240 xref: HGNC:HGNC:17270 xref: UniGene:Hs.397891 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055749 ! Q05BE4_HUMAN relationship: codes_for CCO:B0058375 ! PASK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019303 name: PATZ1_human def: "POZ-, AT hook-, and zinc finger-containing protein 1 gene" [UniProtKB:Q9HBE1] synonym: "PATZ" EXACT [UniProtKB:Q9HBE1] synonym: "RIAZ" EXACT [UniProtKB:Q9HBE1] synonym: "ZBTB19" EXACT [UniProtKB:Q9HBE1] synonym: "ZNF278" EXACT [UniProtKB:Q9HBE1] synonym: "ZSG" EXACT [UniProtKB:Q9HBE1] xref: EMBL:AC005003 xref: EMBL:AF119256 xref: EMBL:AF254082 xref: EMBL:AF254083 xref: EMBL:AF254084 xref: EMBL:AF254085 xref: EMBL:AL096880 xref: EMBL:AY028384 xref: EMBL:BC021091 xref: EMBL:CR456613 xref: HGNC:HGNC:13071 xref: UniGene:Hs.517557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058782 ! PATZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019304 name: PAWR_human def: "PRKC apoptosis WT1 regulator protein gene" [UniProtKB:Q96IZ0] synonym: "PAR4" EXACT [UniProtKB:Q96IZ0] xref: EMBL:AF503628 xref: EMBL:AY300794 xref: EMBL:BC007018 xref: EMBL:CR536549 xref: EMBL:U63809 xref: HGNC:HGNC:8614 xref: UniGene:Hs.643130 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058234 ! PAWR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019305 name: PAX1_human def: "Paired box protein Pax-1 gene" [UniProtKB:P15863] synonym: "HUP48" EXACT [UniProtKB:P15863] xref: EMBL:AL035562 xref: EMBL:AY740018 xref: EMBL:BC069134 xref: EMBL:X15044 xref: HGNC:HGNC:8615 xref: UniGene:Hs.349082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055043 ! PAX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019306 name: PAX2_human def: "Paired box protein Pax-2 gene" [UniProtKB:Q02962] xref: EMBL:AL138762 xref: EMBL:AL589862 xref: EMBL:CH471066 xref: EMBL:L09746 xref: EMBL:L09747 xref: EMBL:L09748 xref: EMBL:L25597 xref: EMBL:M89470 xref: EMBL:U45245 xref: EMBL:U45246 xref: EMBL:U45247 xref: EMBL:U45248 xref: EMBL:U45249 xref: EMBL:U45250 xref: EMBL:U45251 xref: EMBL:U45253 xref: EMBL:U45254 xref: EMBL:U45255 xref: HGNC:HGNC:8616 xref: UniGene:Hs.155644 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031661 ! PAX2_HUMAN relationship: codes_for CCO:B0056559 ! Q5SZP2_HUMAN relationship: codes_for CCO:B0056560 ! Q5SZP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019307 name: PAX3_human def: "Paired box protein Pax-3 gene" [UniProtKB:P23760] synonym: "HUP2" EXACT [UniProtKB:P23760] xref: EMBL:AK291278 xref: EMBL:BC101299 xref: EMBL:BC101300 xref: EMBL:BC101301 xref: EMBL:BC101302 xref: EMBL:BC114363 xref: EMBL:CH471063 xref: EMBL:L10614 xref: EMBL:S69369 xref: EMBL:S69370 xref: EMBL:S83614 xref: EMBL:U12258 xref: EMBL:U12259 xref: EMBL:U12260 xref: EMBL:U12262 xref: EMBL:U12263 xref: EMBL:X15043 xref: EMBL:X15252 xref: EMBL:X15253 xref: EMBL:Z29972 xref: EMBL:Z29973 xref: EMBL:Z29974 xref: HGNC:HGNC:8617 xref: UniGene:Hs.42146 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055164 ! PAX3_HUMAN relationship: codes_for CCO:B0056291 ! Q494Z3_HUMAN relationship: codes_for CCO:B0056292 ! Q494Z4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019308 name: PAX4_human def: "Paired box protein Pax-4 gene" [UniProtKB:O43316] xref: EMBL:AB008913 xref: EMBL:AF043978 xref: EMBL:BC074761 xref: EMBL:BC107150 xref: EMBL:CH236947 xref: EMBL:CH471070 xref: HGNC:HGNC:8618 xref: UniGene:Hs.129706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053749 ! A4D0Z1_HUMAN relationship: codes_for CCO:B0054471 ! PAX4_HUMAN relationship: codes_for CCO:B0056249 ! Q3KNR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019309 name: PAX6_human def: "Paired box protein Pax-6 gene" [UniProtKB:P26367] synonym: "AN2" EXACT [UniProtKB:P26367] xref: EMBL:AY047583 xref: EMBL:BC011953 xref: EMBL:BX640762 xref: EMBL:M77844 xref: EMBL:M93650 xref: EMBL:Z83307 xref: EMBL:Z95332 xref: HGNC:HGNC:8620 xref: UniGene:Hs.591993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031654 ! PAX6_HUMAN relationship: codes_for CCO:B0054284 ! B1B1I8_HUMAN relationship: codes_for CCO:B0054285 ! B1B1I9_HUMAN relationship: codes_for CCO:B0054286 ! B1B1J0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019310 name: PAX7_human def: "Paired box protein Pax-7 gene" [UniProtKB:P23759] synonym: "HUP1" EXACT [UniProtKB:P23759] xref: EMBL:AL021528 xref: EMBL:X15042 xref: EMBL:X15250 xref: EMBL:X15251 xref: EMBL:X96743 xref: EMBL:X96744 xref: EMBL:X96745 xref: EMBL:X96746 xref: EMBL:X96747 xref: EMBL:X96748 xref: EMBL:Z35141 xref: HGNC:HGNC:8621 xref: UniGene:Hs.113253 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055163 ! PAX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019311 name: PAX8_human def: "Paired box protein Pax-8 gene" [UniProtKB:Q06710] xref: EMBL:AC016683 xref: EMBL:AK292191 xref: EMBL:BC001060 xref: EMBL:CH471217 xref: EMBL:L19606 xref: EMBL:S77904 xref: EMBL:S77905 xref: EMBL:S77906 xref: EMBL:X69699 xref: HGNC:HGNC:8622 xref: UniGene:Hs.469728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055771 ! PAX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019312 name: PAX9_human def: "Paired box protein Pax-9 gene" [UniProtKB:P55771] xref: EMBL:AJ238381 xref: EMBL:AJ238382 xref: EMBL:AJ238383 xref: EMBL:BC001159 xref: EMBL:L09745 xref: EMBL:X92850 xref: HGNC:HGNC:8623 xref: UniGene:Hs.132576 xref: UniGene:Hs.609574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055536 ! PAX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019313 name: PBXIP1_human def: "Pre-B-cell leukemia transcription factor-interacting protein 1 gene" [UniProtKB:Q96AQ6] synonym: "HPIP" EXACT [UniProtKB:Q96AQ6] xref: EMBL:AF221521 xref: EMBL:AK022497 xref: EMBL:AK023219 xref: EMBL:AL451085 xref: EMBL:BC016852 xref: EMBL:CH471121 xref: HGNC:HGNC:21199 xref: UniGene:Hs.505806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058154 ! PBIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019314 name: PBX1_human def: "Pre-B-cell leukemia transcription factor 1 gene" [UniProtKB:P40424] synonym: "PRL" EXACT [UniProtKB:P40424] xref: EMBL:AF313396 xref: EMBL:AF313397 xref: EMBL:AF313398 xref: EMBL:AF313399 xref: EMBL:AF313400 xref: EMBL:AF313401 xref: EMBL:AF313402 xref: EMBL:AF313403 xref: EMBL:AF313404 xref: EMBL:AL357568 xref: EMBL:AL359255 xref: EMBL:AL390119 xref: EMBL:BC101578 xref: EMBL:M31522 xref: EMBL:M86546 xref: HGNC:HGNC:8632 xref: UniGene:Hs.654412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055329 ! PBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019315 name: PBX3_human def: "Pre-B-cell leukemia transcription factor 3 gene" [UniProtKB:P40426] xref: EMBL:AF355141 xref: EMBL:AF355142 xref: EMBL:AL358074 xref: EMBL:AL445186 xref: EMBL:BC094883 xref: EMBL:X59841 xref: HGNC:HGNC:8634 xref: UniGene:Hs.428027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055330 ! PBX3_HUMAN relationship: codes_for CCO:B0056476 ! Q5JS98_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019316 name: PBX4_human def: "Pre-B-cell leukemia transcription factor 4 gene" [UniProtKB:Q9BYU1] xref: EMBL:AJ300182 xref: EMBL:AK097427 xref: EMBL:BC033067 xref: HGNC:HGNC:13403 xref: UniGene:Hs.466257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058582 ! PBX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019317 name: PCDH24_human def: "Protocadherin-24 precursor gene" [UniProtKB:Q9BYE9] synonym: "PCLKC" EXACT [UniProtKB:Q9BYE9] xref: EMBL:AB047004 xref: EMBL:AC091934 xref: EMBL:AK000131 xref: HGNC:HGNC:18231 xref: UniGene:Hs.4205 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058577 ! PCD24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019318 name: PCGF1_human def: "Polycomb group RING finger protein 1 gene" [UniProtKB:Q9BSM1] synonym: "NSPC1" EXACT [UniProtKB:Q9BSM1] synonym: "RNF68" EXACT [UniProtKB:Q9BSM1] xref: EMBL:AF087884 xref: EMBL:BC004952 xref: HGNC:HGNC:17615 xref: UniGene:Hs.316750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058507 ! PCGF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019319 name: PCGF2_human def: "Polycomb group RING finger protein 2 gene" [UniProtKB:P35227] synonym: "MEL18" EXACT [UniProtKB:P35227] synonym: "RNF110" EXACT [UniProtKB:P35227] synonym: "ZNF144" EXACT [UniProtKB:P35227] xref: EMBL:AC006449 xref: EMBL:BC004858 xref: EMBL:BC024255 xref: EMBL:CH471152 xref: EMBL:D13969 xref: HGNC:HGNC:12929 xref: UniGene:Hs.371617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055280 ! PCGF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019320 name: PCGF3_human def: "Polycomb group RING finger protein 3 gene" [UniProtKB:Q3KNV8] synonym: "RNF3" EXACT [UniProtKB:Q3KNV8] synonym: "RNF3A" EXACT [UniProtKB:Q3KNV8] xref: EMBL:AJ001019 xref: EMBL:BC107061 xref: HGNC:HGNC:10066 xref: UniGene:Hs.144309 xref: UniGene:Hs.701155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056251 ! PCGF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019321 name: PCGF5_human def: "Polycomb group RING finger protein 5 gene" [UniProtKB:Q86SE9] synonym: "RNF159" EXACT [UniProtKB:Q86SE9] xref: EMBL:AL832003 xref: EMBL:AL832496 xref: EMBL:BC007377 xref: EMBL:BC051845 xref: HGNC:HGNC:28264 xref: UniGene:Hs.500512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057222 ! PCGF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019322 name: PCP2_human def: "Purkinje cell protein 2 homolog gene" [UniProtKB:Q8IVA1] xref: EMBL:BC025387 xref: EMBL:BC038715 xref: HGNC:HGNC:30209 xref: UniGene:Hs.591400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057341 ! PCP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019323 name: PCSK1N_human def: "ProSAAS precursor gene" [UniProtKB:Q9UHG2] xref: EMBL:AF181562 xref: EMBL:BC002851 xref: HGNC:HGNC:17301 xref: UniGene:Hs.522640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059139 ! PCSK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019324 name: PCSK6_human def: "Proprotein convertase subtilisin/kexin type 6 precursor gene" [UniProtKB:P29122] synonym: "PACE4" EXACT [UniProtKB:P29122] xref: EMBL:AB001914 xref: EMBL:D28513 xref: EMBL:D28514 xref: EMBL:D87993 xref: EMBL:D87994 xref: EMBL:D87995 xref: EMBL:M80482 xref: HGNC:HGNC:8569 xref: UniGene:Hs.498494 xref: UniGene:Hs.665989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023795 ! PCSK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019325 name: PCSK9_human def: "Proprotein convertase subtilisin/kexin type 9 precursor gene" [UniProtKB:Q8NBP7] synonym: "NARC1" EXACT [UniProtKB:Q8NBP7] synonym: "PSEC0052" EXACT [UniProtKB:Q8NBP7] xref: EMBL:AC091609 xref: EMBL:AK075365 xref: EMBL:AK124635 xref: EMBL:AL589790 xref: EMBL:AX127530 xref: EMBL:AY829011 xref: EMBL:CH471059 xref: EMBL:EF692496 xref: HGNC:HGNC:20001 xref: UniGene:Hs.18844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057558 ! PCSK9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019326 name: CD274_human def: "Programmed cell death 1 ligand 1 precursor gene" [UniProtKB:Q9NZQ7] synonym: "B7H1" EXACT [UniProtKB:Q9NZQ7] synonym: "PDCD1L1" EXACT [UniProtKB:Q9NZQ7] synonym: "PDCD1LG1" EXACT [UniProtKB:Q9NZQ7] synonym: "PDL1" EXACT [UniProtKB:Q9NZQ7] xref: EMBL:AF177937 xref: EMBL:AF233516 xref: EMBL:AK001894 xref: EMBL:AL162253 xref: EMBL:AY254342 xref: EMBL:AY291313 xref: EMBL:AY714881 xref: EMBL:BC069381 xref: EMBL:BC074984 xref: EMBL:BC113734 xref: EMBL:BC113736 xref: HGNC:HGNC:17635 xref: UniGene:Hs.521989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059011 ! PD1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019327 name: PTGDR_human def: "Prostaglandin D2 receptor gene" [UniProtKB:Q13258] xref: EMBL:BC040968 xref: EMBL:U31098 xref: EMBL:U31099 xref: EMBL:U31332 xref: HGNC:HGNC:9591 xref: UniGene:Hs.306831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055890 ! PD2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019328 name: PDCD6_human def: "Programmed cell death protein 6 gene" [UniProtKB:O75340] synonym: "ALG2" EXACT [UniProtKB:O75340] xref: EMBL:AF035606 xref: EMBL:BC012384 xref: EMBL:BC106706 xref: EMBL:BT020072 xref: EMBL:U58773 xref: HGNC:HGNC:8765 xref: UniGene:Hs.50823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054618 ! PDCD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019329 name: PDCD7_human def: "Programmed cell death protein 7 gene" [UniProtKB:Q8N8D1] xref: EMBL:AF083930 xref: EMBL:AK096970 xref: EMBL:BC016992 xref: EMBL:BT007395 xref: HGNC:HGNC:8767 xref: UniGene:Hs.458596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057517 ! PDCD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019330 name: PDE10A_human def: "cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A gene" [UniProtKB:Q9Y233] xref: EMBL:AB020593 xref: EMBL:AF127479 xref: EMBL:AF127480 xref: EMBL:AL117345 xref: EMBL:AL136130 xref: EMBL:AL160160 xref: EMBL:BC104858 xref: EMBL:BC104860 xref: HGNC:HGNC:8772 xref: UniGene:Hs.584856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059289 ! PDE10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019331 name: PDE11A_human def: "Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A gene" [UniProtKB:Q9HCR9] xref: EMBL:AB036704 xref: EMBL:AB038041 xref: EMBL:AB048423 xref: EMBL:AC011998 xref: EMBL:AC012499 xref: EMBL:AC073834 xref: EMBL:AC073892 xref: EMBL:AC083824 xref: EMBL:AF281865 xref: EMBL:AJ251509 xref: EMBL:AJ278682 xref: EMBL:BC112393 xref: EMBL:BC114431 xref: HGNC:HGNC:8773 xref: UniGene:Hs.570273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058818 ! PDE11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019332 name: PDE1A_human def: "Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A gene" [UniProtKB:P54750] xref: EMBL:AB038224 xref: EMBL:AJ401610 xref: EMBL:AL110263 xref: EMBL:BC022480 xref: EMBL:U40370 xref: HGNC:HGNC:8774 xref: UniGene:Hs.191046 xref: UniGene:Hs.680373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055515 ! PDE1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019333 name: PDE1B_human def: "Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B gene" [UniProtKB:Q01064] synonym: "PDE1B1" EXACT [UniProtKB:Q01064] synonym: "PDES1B" EXACT [UniProtKB:Q01064] xref: EMBL:BC032226 xref: EMBL:M94539 xref: EMBL:U56976 xref: EMBL:U86078 xref: HGNC:HGNC:8775 xref: UniGene:Hs.530871 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055683 ! PDE1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019334 name: PDE1C_human def: "Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C gene" [UniProtKB:Q14123] xref: EMBL:U40371 xref: EMBL:U40372 xref: HGNC:HGNC:8776 xref: UniGene:Hs.655694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055959 ! PDE1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019335 name: PDE2A_human def: "cGMP-dependent 3',5'-cyclic phosphodiesterase gene" [UniProtKB:O00408] xref: EMBL:U67733 xref: HGNC:HGNC:8777 xref: UniGene:Hs.503163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054317 ! PDE2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019336 name: PDE3A_human def: "cGMP-inhibited 3',5'-cyclic phosphodiesterase A gene" [UniProtKB:Q14432] xref: EMBL:AJ005036 xref: EMBL:BC117369 xref: EMBL:BC117371 xref: EMBL:M91667 xref: EMBL:U36798 xref: HGNC:HGNC:8778 xref: UniGene:Hs.591150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055982 ! PDE3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019337 name: PDE3B_human def: "cGMP-inhibited 3',5'-cyclic phosphodiesterase B gene" [UniProtKB:Q13370] xref: EMBL:D50640 xref: EMBL:U38178 xref: EMBL:X95520 xref: HGNC:HGNC:8779 xref: UniGene:Hs.656437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055902 ! PDE3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019338 name: PDE4A_human def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4A gene" [UniProtKB:P27815] synonym: "DPDE2" EXACT [UniProtKB:P27815] xref: EMBL:AF069487 xref: EMBL:AF069488 xref: EMBL:AF069489 xref: EMBL:AF069490 xref: EMBL:AF069491 xref: EMBL:AY593872 xref: EMBL:BC019864 xref: EMBL:L20965 xref: EMBL:M37744 xref: EMBL:S75213 xref: EMBL:U18087 xref: EMBL:U18088 xref: EMBL:U68532 xref: EMBL:U97584 xref: HGNC:HGNC:8780 xref: UniGene:Hs.89901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055195 ! PDE4A_HUMAN relationship: codes_for CCO:B0056925 ! Q6PMT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019339 name: PDE4B_human def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4B gene" [UniProtKB:Q07343] synonym: "DPDE4" EXACT [UniProtKB:Q07343] xref: EMBL:AL109926 xref: EMBL:AL359701 xref: EMBL:CH471059 xref: EMBL:L20966 xref: EMBL:L20971 xref: EMBL:M97515 xref: EMBL:U85048 xref: HGNC:HGNC:8781 xref: UniGene:Hs.198072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055784 ! PDE4B_HUMAN relationship: codes_for CCO:B0056614 ! Q5TEK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019340 name: PDE4C_human def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4C gene" [UniProtKB:Q08493] synonym: "DPDE1" EXACT [UniProtKB:Q08493] xref: EMBL:AC005759 xref: EMBL:AF157811 xref: EMBL:AF157812 xref: EMBL:AF157814 xref: EMBL:AF157815 xref: EMBL:AF157816 xref: EMBL:L20968 xref: EMBL:U66349 xref: EMBL:Z46632 xref: HGNC:HGNC:8782 xref: UniGene:Hs.132584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054527 ! O43851_HUMAN relationship: codes_for CCO:B0055790 ! PDE4C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019341 name: PDE4D_human def: "cAMP-specific 3',5'-cyclic phosphodiesterase 4D gene" [UniProtKB:Q08499] synonym: "DPDE3" EXACT [UniProtKB:Q08499] xref: EMBL:AF012073 xref: EMBL:AF012074 xref: EMBL:AF536975 xref: EMBL:AF536976 xref: EMBL:AF536977 xref: EMBL:AJ250854 xref: EMBL:AY245866 xref: EMBL:AY245867 xref: EMBL:AY388960 xref: EMBL:BC008390 xref: EMBL:BC036319 xref: EMBL:BT007398 xref: EMBL:L20969 xref: EMBL:L20970 xref: EMBL:U02882 xref: EMBL:U50157 xref: EMBL:U50158 xref: EMBL:U50159 xref: HGNC:HGNC:8783 xref: UniGene:Hs.117545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055792 ! PDE4D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019342 name: PDE5A_human def: "cGMP-specific 3',5'-cyclic phosphodiesterase gene" [UniProtKB:O76074] synonym: "PDE5" EXACT [UniProtKB:O76074] xref: EMBL:AB001635 xref: EMBL:AB015656 xref: EMBL:AC093752 xref: EMBL:AF043731 xref: EMBL:AF043732 xref: EMBL:AJ004865 xref: EMBL:AY264918 xref: EMBL:AY266363 xref: EMBL:BC126233 xref: EMBL:D89094 xref: HGNC:HGNC:8784 xref: UniGene:Hs.647971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054692 ! PDE5A_HUMAN relationship: codes_for CCO:B0056336 ! Q4W5L4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019343 name: PDE6A_human def: "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha gene" [UniProtKB:P16499] synonym: "PDEA" EXACT [UniProtKB:P16499] xref: EMBL:BC035909 xref: EMBL:CH471062 xref: EMBL:M26061 xref: HGNC:HGNC:8785 xref: UniGene:Hs.567314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055055 ! PDE6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019344 name: PDE6B_human def: "Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor gene" [UniProtKB:P35913] synonym: "PDEB" EXACT [UniProtKB:P35913] xref: EMBL:BC000249 xref: EMBL:S41458 xref: EMBL:X62692 xref: EMBL:X62693 xref: EMBL:X62694 xref: EMBL:X62695 xref: EMBL:X66142 xref: EMBL:X90587 xref: EMBL:X90588 xref: EMBL:X90589 xref: EMBL:X90590 xref: HGNC:HGNC:8786 xref: UniGene:Hs.59872 xref: UniGene:Hs.623810 xref: UniGene:Hs.654544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055303 ! PDE6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019345 name: PDE6C_human def: "Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' gene" [UniProtKB:P51160] synonym: "PDEA2" EXACT [UniProtKB:P51160] xref: EMBL:AL157396 xref: EMBL:AL356214 xref: EMBL:CH471066 xref: EMBL:U20196 xref: EMBL:U20197 xref: EMBL:U20199 xref: EMBL:U20200 xref: EMBL:U20201 xref: EMBL:U20202 xref: EMBL:U20203 xref: EMBL:U20204 xref: EMBL:U20205 xref: EMBL:U20206 xref: EMBL:U20207 xref: EMBL:U20208 xref: EMBL:U20209 xref: EMBL:U20210 xref: EMBL:U20211 xref: EMBL:U20212 xref: EMBL:U31973 xref: EMBL:X94354 xref: HGNC:HGNC:8787 xref: UniGene:Hs.658121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055460 ! PDE6C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019346 name: PDE8A_human def: "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A gene" [UniProtKB:O60658] xref: EMBL:AF056490 xref: EMBL:AF388183 xref: EMBL:AF388184 xref: EMBL:AF388185 xref: EMBL:AF388186 xref: EMBL:AF388187 xref: EMBL:AL109687 xref: EMBL:AL109778 xref: EMBL:BC075822 xref: HGNC:HGNC:8793 xref: UniGene:Hs.9333 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054571 ! PDE8A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019347 name: PDE8B_human def: "High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B gene" [UniProtKB:O95263] xref: EMBL:AB085824 xref: EMBL:AB085825 xref: EMBL:AB085826 xref: EMBL:AB085827 xref: EMBL:AF079529 xref: EMBL:AL831924 xref: EMBL:AY129948 xref: EMBL:AY129949 xref: EMBL:AY129950 xref: EMBL:BC043209 xref: HGNC:HGNC:8794 xref: UniGene:Hs.584830 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054742 ! PDE8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019348 name: PDE9A_human def: "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A gene" [UniProtKB:O76083] xref: EMBL:AB017602 xref: EMBL:AF048837 xref: EMBL:AF067223 xref: EMBL:AF067224 xref: EMBL:AF067225 xref: EMBL:AF067226 xref: EMBL:AP001747 xref: EMBL:AY196299 xref: EMBL:AY196300 xref: EMBL:AY196301 xref: EMBL:AY196302 xref: EMBL:AY196303 xref: EMBL:AY196304 xref: EMBL:AY196305 xref: EMBL:AY196306 xref: EMBL:AY196307 xref: EMBL:AY196308 xref: EMBL:AY196309 xref: EMBL:AY196310 xref: EMBL:AY196311 xref: EMBL:AY196312 xref: EMBL:AY196313 xref: EMBL:AY196314 xref: EMBL:AY242121 xref: EMBL:AY701187 xref: EMBL:BC009047 xref: HGNC:HGNC:8795 xref: UniGene:Hs.473927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054693 ! PDE9A_HUMAN relationship: codes_for CCO:B0056525 ! Q5QD39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019349 name: PDIA2_human def: "Protein disulfide-isomerase A2 precursor gene" [UniProtKB:Q13087] synonym: "PDIP" EXACT [UniProtKB:Q13087] xref: EMBL:AE006463 xref: EMBL:BC000537 xref: EMBL:U19948 xref: HGNC:HGNC:14180 xref: UniGene:Hs.66581 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020068 ! PDIA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019350 name: PDPN_human def: "Podoplanin precursor gene" [UniProtKB:Q86YL7] synonym: "GP36" EXACT [UniProtKB:Q86YL7] synonym: "PSEC0003" EXACT [UniProtKB:Q86YL7] synonym: "PSEC0025" EXACT [UniProtKB:Q86YL7] xref: EMBL:AB127958 xref: EMBL:AF030427 xref: EMBL:AF030428 xref: EMBL:AF390106 xref: EMBL:AJ225022 xref: EMBL:AK075327 xref: EMBL:AK075345 xref: EMBL:AL354712 xref: EMBL:AL359771 xref: EMBL:AY194238 xref: EMBL:BC014668 xref: EMBL:BC022812 xref: HGNC:HGNC:29602 xref: UniGene:Hs.468675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057306 ! PDPN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019351 name: PDYN_human def: "Beta-neoendorphin-dynorphin precursor gene" [UniProtKB:P01213] xref: EMBL:AL034562 xref: EMBL:BC026334 xref: EMBL:K02267 xref: EMBL:K02268 xref: EMBL:X00176 xref: EMBL:X02536 xref: HGNC:HGNC:8820 xref: UniGene:Hs.22584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054837 ! PDYN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019352 name: PDZK1_human def: "PDZ domain-containing protein 1 gene" [UniProtKB:Q5T2W1] synonym: "CAP70" EXACT [UniProtKB:Q5T2W1] synonym: "NHERF3" EXACT [UniProtKB:Q5T2W1] synonym: "PDZD1" EXACT [UniProtKB:Q5T2W1] xref: EMBL:AF012281 xref: EMBL:AL390725 xref: EMBL:BC006496 xref: EMBL:BC006518 xref: HGNC:HGNC:8821 xref: UniGene:Hs.444751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025068 ! PDZD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019353 name: PDZD3_human def: "PDZ domain-containing protein 3 gene" [UniProtKB:Q86UT5] synonym: "DLNB27" EXACT [UniProtKB:Q86UT5] synonym: "IKEPP" EXACT [UniProtKB:Q86UT5] synonym: "PDZK2" EXACT [UniProtKB:Q86UT5] xref: EMBL:AB094096 xref: EMBL:AK026409 xref: EMBL:AK091966 xref: EMBL:AY047359 xref: EMBL:BC029042 xref: HGNC:HGNC:19891 xref: UniGene:Hs.374726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025070 ! PDZD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019354 name: PDZD8_human def: "PDZ domain-containing protein 8 gene" [UniProtKB:Q8NEN9] synonym: "PDZK8" EXACT [UniProtKB:Q8NEN9] xref: EMBL:AL122051 xref: EMBL:AL359836 xref: EMBL:AL391988 xref: EMBL:AY211924 xref: EMBL:AY211929 xref: EMBL:BC028375 xref: HGNC:HGNC:26974 xref: UniGene:Hs.501149 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057592 ! PDZD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019355 name: PTGER1_human def: "Prostaglandin E2 receptor EP1 subtype gene" [UniProtKB:P34995] xref: EMBL:AB065464 xref: EMBL:AY275470 xref: EMBL:BC039034 xref: EMBL:BC051286 xref: EMBL:L22647 xref: HGNC:HGNC:9593 xref: UniGene:Hs.159360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055275 ! PE2R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019356 name: PTGER2_human def: "Prostaglandin E2 receptor EP2 subtype gene" [UniProtKB:P43116] xref: EMBL:AF134201 xref: EMBL:AF134202 xref: EMBL:AY275471 xref: EMBL:BC093927 xref: EMBL:BC093929 xref: EMBL:DQ398948 xref: EMBL:U19487 xref: EMBL:X83868 xref: HGNC:HGNC:9594 xref: UniGene:Hs.2090 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055359 ! PE2R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019357 name: PTGER4_human def: "Prostaglandin E2 receptor EP4 subtype gene" [UniProtKB:P35408] synonym: "PTGER2" EXACT [UniProtKB:P35408] xref: EMBL:AY429109 xref: EMBL:BC101534 xref: EMBL:BC113523 xref: EMBL:D28472 xref: EMBL:DQ400918 xref: EMBL:L25124 xref: EMBL:L28175 xref: EMBL:X97873 xref: EMBL:X97874 xref: HGNC:HGNC:9596 xref: UniGene:Hs.199248 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055288 ! PE2R4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019358 name: PEA15_human def: "Astrocytic phosphoprotein PEA-15 gene" [UniProtKB:Q15121] xref: EMBL:AF153273 xref: EMBL:AF153274 xref: EMBL:AK095879 xref: EMBL:AL121987 xref: EMBL:BC002426 xref: EMBL:BC022554 xref: EMBL:BT007252 xref: EMBL:CH471121 xref: EMBL:X86809 xref: EMBL:Y13736 xref: HGNC:HGNC:8822 xref: UniGene:Hs.517216 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054233 ! B1AKZ3_HUMAN relationship: codes_for CCO:B0054234 ! B1AKZ5_HUMAN relationship: codes_for CCO:B0056045 ! PEA15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019359 name: PECR_human def: "Peroxisomal trans-2-enoyl-CoA reductase gene" [UniProtKB:Q9BY49] synonym: "PRO1004" EXACT [UniProtKB:Q9BY49] xref: EMBL:AC010686 xref: EMBL:AF119841 xref: EMBL:AF212234 xref: EMBL:AF232009 xref: EMBL:AJ250303 xref: EMBL:BC002529 xref: EMBL:CR457145 xref: HGNC:HGNC:18281 xref: UniGene:Hs.281680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058571 ! PECR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019360 name: SERPINF1_human def: "Pigment epithelium-derived factor precursor gene" [UniProtKB:P36955] synonym: "PEDF" EXACT [UniProtKB:P36955] xref: EMBL:AF400442 xref: EMBL:BC000522 xref: EMBL:BC013984 xref: EMBL:BT007222 xref: EMBL:M76979 xref: EMBL:M90439 xref: EMBL:U29953 xref: EMBL:U57445 xref: EMBL:U57446 xref: EMBL:U57447 xref: EMBL:U57448 xref: EMBL:U57449 xref: EMBL:U57450 xref: HGNC:HGNC:8824 xref: UniGene:Hs.532768 xref: UniGene:Hs.694727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055315 ! PEDF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019361 name: PEG3_human def: "Paternally-expressed gene 3 protein gene" [UniProtKB:Q9GZU2] synonym: "KIAA0287" EXACT [UniProtKB:Q9GZU2] synonym: "ZSCAN24" EXACT [UniProtKB:Q9GZU2] xref: EMBL:AB003039 xref: EMBL:AC006115 xref: EMBL:AF208967 xref: EMBL:AF208968 xref: EMBL:AF208969 xref: EMBL:AF208970 xref: EMBL:AF208974 xref: EMBL:AF208975 xref: EMBL:AF208976 xref: EMBL:AF208977 xref: EMBL:AF208978 xref: EMBL:AF208979 xref: EMBL:AF208980 xref: EMBL:BC052616 xref: EMBL:CR933682 xref: EMBL:U90336 xref: HGNC:HGNC:8826 xref: UniGene:Hs.201776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054088 ! A8MX22_HUMAN relationship: codes_for CCO:B0058637 ! PEG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019362 name: PEMT_human def: "Phosphatidylethanolamine N-methyltransferase gene" [UniProtKB:Q9UBM1] synonym: "PEMPT" EXACT [UniProtKB:Q9UBM1] synonym: "PNMT" EXACT [UniProtKB:Q9UBM1] xref: EMBL:AB029821 xref: EMBL:AF113126 xref: EMBL:AF176806 xref: EMBL:AF176807 xref: EMBL:AF294463 xref: EMBL:AF294464 xref: EMBL:AF294465 xref: EMBL:AF294466 xref: EMBL:AF294467 xref: EMBL:AF294468 xref: HGNC:HGNC:8830 xref: UniGene:Hs.287717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059077 ! PEMT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019363 name: PSENEN_human def: "Gamma-secretase subunit PEN-2 gene" [UniProtKB:Q9NZ42] synonym: "MDS033" EXACT [UniProtKB:Q9NZ42] synonym: "PEN2" EXACT [UniProtKB:Q9NZ42] xref: EMBL:AF220053 xref: EMBL:BC009575 xref: HGNC:HGNC:30100 xref: UniGene:Hs.534465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058989 ! PEN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019364 name: PENK_human def: "Proenkephalin A precursor gene" [UniProtKB:P01210] xref: EMBL:BC032505 xref: EMBL:J00122 xref: EMBL:J00123 xref: EMBL:V00509 xref: HGNC:HGNC:8831 xref: UniGene:Hs.339831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054836 ! PENK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019365 name: PEO1_human def: "Twinkle protein, mitochondrial precursor gene" [UniProtKB:Q96RR1] synonym: "C10orf2" EXACT [UniProtKB:Q96RR1] xref: EMBL:AF292004 xref: EMBL:AF292005 xref: EMBL:AL133215 xref: EMBL:BC013349 xref: EMBL:BX640829 xref: HGNC:HGNC:1160 xref: UniGene:Hs.22678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058382 ! PEO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019366 name: PER1_human def: "Period circadian protein homolog 1 gene" [UniProtKB:O15534] synonym: "KIAA0482" EXACT [UniProtKB:O15534] synonym: "PER" EXACT [UniProtKB:O15534] synonym: "RIGUI" EXACT [UniProtKB:O15534] xref: EMBL:AB002107 xref: EMBL:AB030817 xref: EMBL:AB088477 xref: EMBL:AF022991 xref: EMBL:AF102137 xref: EMBL:BC028207 xref: EMBL:CH471108 xref: HGNC:HGNC:8845 xref: UniGene:Hs.445534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054445 ! PER1_HUMAN relationship: codes_for CCO:B0057493 ! Q8N6U1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019367 name: PER2_human def: "Period circadian protein homolog 2 gene" [UniProtKB:O15055] synonym: "KIAA0347" EXACT [UniProtKB:O15055] xref: EMBL:AB002345 xref: EMBL:AB012614 xref: EMBL:AC012485 xref: HGNC:HGNC:8846 xref: UniGene:Hs.58756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054400 ! PER2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019368 name: PER3_human def: "Period circadian protein homolog 3 gene" [UniProtKB:P56645] synonym: "GIG13" EXACT [UniProtKB:P56645] xref: EMBL:AB047521 xref: EMBL:AB047530 xref: EMBL:AB047531 xref: EMBL:AB047532 xref: EMBL:AB047533 xref: EMBL:AB047534 xref: EMBL:AB047686 xref: EMBL:AL157954 xref: EMBL:AY493418 xref: EMBL:BC026102 xref: EMBL:EF015893 xref: EMBL:Z98884 xref: HGNC:HGNC:8847 xref: UniGene:Hs.533339 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022449 ! A2I2N5_HUMAN relationship: codes_for CCO:B0022450 ! Q5H8X5_HUMAN relationship: codes_for CCO:B0022451 ! Q8TAR6_HUMAN relationship: codes_for CCO:B0022452 ! PER3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019369 name: MPO_human def: "Myeloperoxidase precursor gene" [UniProtKB:P05164] xref: EMBL:D14466 xref: EMBL:DQ088846 xref: EMBL:J02694 xref: EMBL:M17170 xref: EMBL:M17171 xref: EMBL:M17172 xref: EMBL:M17173 xref: EMBL:M17174 xref: EMBL:M17175 xref: EMBL:M17176 xref: EMBL:M19507 xref: EMBL:M19508 xref: EMBL:S56200 xref: EMBL:X04876 xref: EMBL:X15377 xref: HGNC:HGNC:7218 xref: UniGene:Hs.458272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054897 ! PERM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019370 name: GIGYF1_human def: "PERQ amino acid-rich with GYF domain-containing protein 1 gene" [UniProtKB:O75420] synonym: "CDS2" EXACT [UniProtKB:O75420] synonym: "PERQ1" EXACT [UniProtKB:O75420] synonym: "PP3360" EXACT [UniProtKB:O75420] xref: EMBL:AF053356 xref: EMBL:AF289554 xref: EMBL:AY176044 xref: HGNC:HGNC:9126 xref: UniGene:Hs.696531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054633 ! PERQ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019371 name: PEX14_human def: "Peroxisomal membrane protein PEX14 gene" [UniProtKB:O75381] xref: EMBL:AB017546 xref: EMBL:AF045186 xref: EMBL:AL139423 xref: EMBL:AL354956 xref: EMBL:AL591403 xref: EMBL:BC006327 xref: EMBL:CR450321 xref: EMBL:CR542083 xref: HGNC:HGNC:8856 xref: UniGene:Hs.149983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054627 ! PEX14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019372 name: PHF21A_human def: "PHD finger protein 21A gene" [UniProtKB:Q96BD5] synonym: "BHC80" EXACT [UniProtKB:Q96BD5] synonym: "BM-006" EXACT [UniProtKB:Q96BD5] synonym: "KIAA1696" EXACT [UniProtKB:Q96BD5] xref: EMBL:AB051483 xref: EMBL:AF208848 xref: EMBL:AK021530 xref: EMBL:AK023258 xref: EMBL:AY090777 xref: EMBL:BC015714 xref: EMBL:BX648236 xref: HGNC:HGNC:24156 xref: UniGene:Hs.502458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058162 ! PF21A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019373 name: PTGFR_human def: "Prostaglandin F2-alpha receptor gene" [UniProtKB:P43088] xref: EMBL:AB041713 xref: EMBL:AF004021 xref: EMBL:AL136324 xref: EMBL:AY337000 xref: EMBL:AY485530 xref: EMBL:BC112965 xref: EMBL:CH471059 xref: EMBL:L24470 xref: HGNC:HGNC:9600 xref: UniGene:Hs.654365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055358 ! PF2R_HUMAN relationship: codes_for CCO:B0056937 ! Q6RYQ6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019374 name: PFDN5_human def: "Prefoldin subunit 5 gene" [UniProtKB:Q99471] synonym: "MM1" EXACT [UniProtKB:Q99471] synonym: "PFD5" EXACT [UniProtKB:Q99471] xref: EMBL:AB055802 xref: EMBL:AB055803 xref: EMBL:BC003373 xref: EMBL:BC062671 xref: EMBL:BT007195 xref: EMBL:D89667 xref: HGNC:HGNC:8869 xref: UniGene:Hs.655327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058416 ! PFD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019375 name: PGBD1_human def: "PiggyBac transposable element-derived protein 1 gene" [UniProtKB:Q96JS3] synonym: "hucep-4" EXACT [UniProtKB:Q96JS3] xref: EMBL:AK223446 xref: EMBL:AL021997 xref: EMBL:BC069033 xref: EMBL:BC128585 xref: EMBL:D88259 xref: HGNC:HGNC:19398 xref: UniGene:Hs.144527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058249 ! PGBD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019376 name: PGBD3_human def: "PiggyBac transposable element-derived protein 3 gene" [UniProtKB:Q8N328] xref: EMBL:AL138760 xref: EMBL:BC028954 xref: EMBL:BC034479 xref: EMBL:BC063690 xref: HGNC:HGNC:19400 xref: UniGene:Hs.654449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057451 ! PGBD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019377 name: PHB2_human def: "Prohibitin-2 gene" [UniProtKB:Q99623] synonym: "BAP" EXACT [UniProtKB:Q99623] synonym: "REA" EXACT [UniProtKB:Q99623] xref: EMBL:AF126021 xref: EMBL:AF150962 xref: EMBL:AF178980 xref: EMBL:BC014766 xref: EMBL:BC110322 xref: EMBL:U47924 xref: EMBL:U72511 xref: HGNC:HGNC:30306 xref: UniGene:Hs.504620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058432 ! PHB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019378 name: PHF10_human def: "PHD finger protein 10 gene" [UniProtKB:Q8WUB8] xref: EMBL:AF338735 xref: EMBL:AK001837 xref: EMBL:AL513547 xref: EMBL:BC020954 xref: EMBL:BC110323 xref: EMBL:CR457273 xref: HGNC:HGNC:18250 xref: UniGene:Hs.435933 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057976 ! PHF10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019379 name: PHF19_human def: "PHD finger protein 19 gene" [UniProtKB:Q5T6S3] synonym: "PCL3" EXACT [UniProtKB:Q5T6S3] xref: EMBL:AL117477 xref: EMBL:AL161911 xref: EMBL:AL354792 xref: EMBL:BC022374 xref: EMBL:BC108663 xref: EMBL:BC125076 xref: EMBL:BC125077 xref: EMBL:BX640713 xref: HGNC:HGNC:24566 xref: UniGene:Hs.460124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056591 ! PHF19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019380 name: PHF20_human def: "PHD finger protein 20 gene" [UniProtKB:Q9BVI0] synonym: "C20orf104" EXACT [UniProtKB:Q9BVI0] synonym: "GLEA2" EXACT [UniProtKB:Q9BVI0] synonym: "HCA58" EXACT [UniProtKB:Q9BVI0] synonym: "NZF" EXACT [UniProtKB:Q9BVI0] synonym: "TZP" EXACT [UniProtKB:Q9BVI0] xref: EMBL:AF220416 xref: EMBL:AF258787 xref: EMBL:AF348207 xref: EMBL:AL078461 xref: EMBL:AL109965 xref: EMBL:AY027523 xref: EMBL:BC001198 xref: EMBL:BC048210 xref: HGNC:HGNC:16098 xref: UniGene:Hs.517044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058527 ! PHF20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019381 name: PHF6_human def: "PHD finger protein 6 gene" [UniProtKB:Q8IWS0] synonym: "KIAA1823" EXACT [UniProtKB:Q8IWS0] xref: EMBL:AB058726 xref: EMBL:AC004383 xref: EMBL:AL591668 xref: EMBL:AY157622 xref: EMBL:BC005994 xref: HGNC:HGNC:18145 xref: UniGene:Hs.356501 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057363 ! PHF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019382 name: PHIP_human def: "PH-interacting protein gene" [UniProtKB:Q8WWQ0] synonym: "WDR11" EXACT [UniProtKB:Q8WWQ0] xref: EMBL:AF310250 xref: EMBL:AJ303102 xref: EMBL:AK057039 xref: EMBL:AK075124 xref: EMBL:AL161957 xref: EMBL:AL356776 xref: EMBL:AL450327 xref: EMBL:BC008909 xref: EMBL:BC021905 xref: EMBL:BC081569 xref: EMBL:CH471051 xref: HGNC:HGNC:15673 xref: UniGene:Hs.511817 xref: UniGene:Hs.606356 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058005 ! PHIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019383 name: PDCL_human def: "Phosducin-like protein gene" [UniProtKB:Q13371] xref: EMBL:AF031463 xref: EMBL:AL117602 xref: EMBL:BC017227 xref: EMBL:U38236 xref: HGNC:HGNC:8770 xref: UniGene:Hs.271749 xref: UniGene:Hs.620774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055903 ! PHLP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019384 name: PDC_human def: "Phosducin gene" [UniProtKB:P20941] xref: EMBL:AL596220 xref: EMBL:M33478 xref: EMBL:M38058 xref: EMBL:M38059 xref: EMBL:M60720 xref: HGNC:HGNC:8759 xref: UniGene:Hs.654381 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055129 ! PHOS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019385 name: PCBD2_human def: "Pterin-4-alpha-carbinolamine dehydratase 2 gene" [UniProtKB:Q9H0N5] synonym: "DCOH2" EXACT [UniProtKB:Q9H0N5] synonym: "DCOHM" EXACT [UniProtKB:Q9H0N5] xref: EMBL:AF499009 xref: EMBL:AL136721 xref: EMBL:BC054021 xref: HGNC:HGNC:24474 xref: UniGene:Hs.631804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058656 ! PHS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019386 name: PCBD1_human def: "Pterin-4-alpha-carbinolamine dehydratase gene" [UniProtKB:P61457] synonym: "DCOH" EXACT [UniProtKB:P61457] synonym: "PCBD" EXACT [UniProtKB:P61457] xref: EMBL:AF082858 xref: EMBL:BC006324 xref: EMBL:L41559 xref: EMBL:L41560 xref: EMBL:M83742 xref: HGNC:HGNC:8646 xref: UniGene:Hs.3192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055611 ! PHS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019387 name: PHTF1_human def: "Putative homeodomain transcription factor 1 gene" [UniProtKB:Q9UMS5] synonym: "PHTF" EXACT [UniProtKB:Q9UMS5] xref: EMBL:AJ011863 xref: EMBL:AL133517 xref: EMBL:AL365321 xref: EMBL:BC002447 xref: HGNC:HGNC:8939 xref: UniGene:Hs.655824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059242 ! PHTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019388 name: PHTF2_human def: "Putative homeodomain transcription factor 2 gene" [UniProtKB:Q8N3S3] xref: EMBL:AL136883 xref: EMBL:AL831969 xref: EMBL:BC127093 xref: EMBL:BC127094 xref: EMBL:CH236949 xref: EMBL:CH471091 xref: HGNC:HGNC:13411 xref: UniGene:Hs.203965 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057457 ! PHTF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019389 name: PHOX2A_human def: "Paired mesoderm homeobox protein 2A gene" [UniProtKB:O14813] synonym: "ARIX" EXACT [UniProtKB:O14813] synonym: "PMX2A" EXACT [UniProtKB:O14813] xref: EMBL:AF022722 xref: EMBL:AF022723 xref: EMBL:AF022724 xref: EMBL:BC041564 xref: HGNC:HGNC:691 xref: UniGene:Hs.697462 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054380 ! PHX2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019390 name: PHOX2B_human def: "Paired mesoderm homeobox protein 2B gene" [UniProtKB:Q99453] synonym: "PMX2B" EXACT [UniProtKB:Q99453] xref: EMBL:AB015671 xref: EMBL:AF117979 xref: EMBL:BC017199 xref: EMBL:D82344 xref: HGNC:HGNC:9143 xref: UniGene:Hs.87202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058412 ! PHX2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019391 name: PTGIR_human def: "Prostacyclin receptor gene" [UniProtKB:P43119] synonym: "PRIPR" EXACT [UniProtKB:P43119] xref: EMBL:AY242134 xref: EMBL:BC075814 xref: EMBL:D25418 xref: EMBL:D29634 xref: EMBL:D38127 xref: EMBL:L29016 xref: HGNC:HGNC:9602 xref: UniGene:Hs.458324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055360 ! PI2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019392 name: PIP4K2B_human def: "Phosphatidylinositol-5-phosphate 4-kinase type-2 beta gene" [UniProtKB:P78356] synonym: "PIP5K2B" EXACT [UniProtKB:P78356] xref: EMBL:BC027459 xref: EMBL:BT019614 xref: EMBL:U85245 xref: HGNC:HGNC:8998 xref: UniGene:Hs.260603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055640 ! PI42B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019393 name: PI4KA_human def: "Phosphatidylinositol 4-kinase alpha gene" [UniProtKB:P42356] synonym: "PIK4" EXACT [UniProtKB:P42356] synonym: "PIK4CA" EXACT [UniProtKB:P42356] xref: EMBL:AF012872 xref: EMBL:BC018120 xref: EMBL:BC053654 xref: EMBL:L36151 xref: HGNC:HGNC:8983 xref: UniGene:Hs.529438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055350 ! PI4KA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019394 name: PI4KB_human def: "Phosphatidylinositol 4-kinase beta gene" [UniProtKB:Q9UBF8] synonym: "PIK4CB" EXACT [UniProtKB:Q9UBF8] xref: EMBL:AB005910 xref: EMBL:AJ011121 xref: EMBL:AJ011122 xref: EMBL:AJ011123 xref: EMBL:AL391069 xref: EMBL:BC000029 xref: EMBL:BC040300 xref: EMBL:U81802 xref: HGNC:HGNC:8984 xref: UniGene:Hs.632465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059072 ! PI4KB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019395 name: PI4KAP1_human def: "Putative phosphatidylinositol 4-kinase alpha-like protein P1 gene" [UniProtKB:Q8N8J0] xref: EMBL:AK096724 xref: EMBL:AK292695 xref: EMBL:BC072398 xref: HGNC:HGNC:33576 xref: UniGene:Hs.448225 xref: UniGene:Hs.592456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057521 ! PI4P1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019396 name: PI4KAP2_human def: "Putative phosphatidylinositol 4-kinase alpha-like protein P2 gene" [UniProtKB:A4QPH2] xref: EMBL:AK126860 xref: EMBL:BC020225 xref: EMBL:BC139841 xref: EMBL:CR456378 xref: HGNC:HGNC:33577 xref: UniGene:Hs.448225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053773 ! PI4P2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019397 name: PIAS3_human def: "E3 SUMO-protein ligase PIAS3 gene" [UniProtKB:Q9Y6X2] xref: EMBL:AB021868 xref: EMBL:BC001154 xref: EMBL:BC030556 xref: HGNC:HGNC:16861 xref: UniGene:Hs.435761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018461 ! PIAS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019398 name: LRDD_human def: "Leucine-rich repeat and death domain-containing protein gene" [UniProtKB:Q9HB75] synonym: "PIDD" EXACT [UniProtKB:Q9HB75] xref: EMBL:AB208832 xref: EMBL:AB208949 xref: EMBL:AB209529 xref: EMBL:AF229178 xref: EMBL:AF274972 xref: EMBL:AF465246 xref: EMBL:AK074893 xref: EMBL:AL833849 xref: EMBL:BC014904 xref: HGNC:HGNC:16491 xref: UniGene:Hs.592290 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058779 ! PIDD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019399 name: PIF1_human def: "ATP-dependent DNA helicase PIF1 gene" [UniProtKB:Q9H611] synonym: "C15orf20" EXACT [UniProtKB:Q9H611] xref: EMBL:AB185926 xref: EMBL:AB185927 xref: EMBL:AK026345 xref: EMBL:AY498716 xref: EMBL:DQ437529 xref: HGNC:HGNC:26220 xref: UniGene:Hs.112160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058731 ! PIF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019400 name: PINK1_human def: "Serine/threonine-protein kinase PINK1, mitochondrial precursor gene" [UniProtKB:Q9BXM7] xref: EMBL:AB053323 xref: EMBL:AF316873 xref: EMBL:AK075225 xref: EMBL:AL391357 xref: EMBL:BC009534 xref: EMBL:BC028215 xref: HGNC:HGNC:14581 xref: UniGene:Hs.389171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058560 ! PINK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019401 name: PITPNC1_human def: "Cytoplasmic phosphatidylinositol transfer protein 1 gene" [UniProtKB:Q9UKF7] xref: EMBL:AF171102 xref: EMBL:BC007905 xref: EMBL:BC067095 xref: HGNC:HGNC:21045 xref: UniGene:Hs.591185 xref: UniGene:Hs.696160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059192 ! PITC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019402 name: PITX1_human def: "Pituitary homeobox 1 gene" [UniProtKB:P78337] synonym: "BFT" EXACT [UniProtKB:P78337] synonym: "PTX1" EXACT [UniProtKB:P78337] xref: EMBL:AC004764 xref: EMBL:AC008406 xref: EMBL:AF009648 xref: EMBL:AF009649 xref: EMBL:AF009650 xref: EMBL:BC003685 xref: EMBL:BC009412 xref: EMBL:U70370 xref: HGNC:HGNC:9004 xref: UniGene:Hs.84136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055638 ! PITX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019403 name: PITX2_human def: "Pituitary homeobox 2 gene" [UniProtKB:Q99697] synonym: "ARP1" EXACT [UniProtKB:Q99697] synonym: "RGS" EXACT [UniProtKB:Q99697] synonym: "RIEG" EXACT [UniProtKB:Q99697] synonym: "RIEG1" EXACT [UniProtKB:Q99697] xref: EMBL:AF048720 xref: EMBL:AF048721 xref: EMBL:AF048722 xref: EMBL:AF238048 xref: EMBL:BC013998 xref: EMBL:U69961 xref: HGNC:HGNC:9005 xref: UniGene:Hs.643588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058441 ! PITX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019404 name: PITX3_human def: "Pituitary homeobox 3 gene" [UniProtKB:O75364] synonym: "PTX3" EXACT [UniProtKB:O75364] xref: EMBL:AF041339 xref: EMBL:AL160011 xref: EMBL:BC011642 xref: HGNC:HGNC:9006 xref: UniGene:Hs.137568 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054624 ! PITX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019405 name: PAK1IP1_human def: "p21-activated protein kinase-interacting protein 1 gene" [UniProtKB:Q9NWT1] synonym: "PIP1" EXACT [UniProtKB:Q9NWT1] synonym: "WDR84" EXACT [UniProtKB:Q9NWT1] xref: EMBL:AF283303 xref: EMBL:AK000631 xref: EMBL:AL358777 xref: EMBL:BC010907 xref: HGNC:HGNC:20882 xref: UniGene:Hs.310231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058940 ! PK1IP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019406 name: PKD1L2_human def: "Polycystic kidney disease protein 1-like 2 precursor gene" [UniProtKB:Q7Z442] synonym: "KIAA1879" EXACT [UniProtKB:Q7Z442] synonym: "PC1L2" EXACT [UniProtKB:Q7Z442] xref: EMBL:AB067466 xref: EMBL:AC092718 xref: EMBL:AC131888 xref: EMBL:AK098052 xref: EMBL:AK127266 xref: EMBL:AK131378 xref: EMBL:AY164483 xref: EMBL:AY371495 xref: EMBL:BC004562 xref: EMBL:BC014157 xref: HGNC:HGNC:21715 xref: UniGene:Hs.413525 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057159 ! PK1L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019407 name: PKD1L3_human def: "Polycystic kidney disease protein 1-like 3 precursor gene" [UniProtKB:Q7Z443] xref: EMBL:AY164485 xref: HGNC:HGNC:21716 xref: UniGene:Hs.675286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057160 ! PK1L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019408 name: PIK3C3_human def: "Phosphatidylinositol 3-kinase catalytic subunit type 3 gene" [UniProtKB:Q8NEB9] xref: EMBL:AC087683 xref: EMBL:BC033004 xref: EMBL:BC053651 xref: EMBL:Z46973 xref: HGNC:HGNC:8974 xref: UniGene:Hs.464971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054130 ! A8MYT4_HUMAN relationship: codes_for CCO:B0057589 ! PK3C3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019409 name: PKD1_human def: "Polycystin-1 precursor gene" [UniProtKB:P98161] xref: EMBL:L33243 xref: EMBL:L39891 xref: EMBL:L43601 xref: EMBL:L43602 xref: EMBL:L43604 xref: EMBL:L43605 xref: EMBL:L43610 xref: EMBL:L43617 xref: EMBL:L43618 xref: EMBL:L43619 xref: EMBL:U24497 xref: HGNC:HGNC:9008 xref: UniGene:Hs.75813 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055670 ! PKD1_HUMAN relationship: codes_for CCO:B0056046 ! Q15142_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019410 name: PLEKHG4B_human def: "Pleckstrin homology domain-containing family G member 4B gene" [UniProtKB:Q96PX9] synonym: "KIAA1909" EXACT [UniProtKB:Q96PX9] xref: EMBL:AB067496 xref: HGNC:HGNC:29399 xref: UniGene:Hs.535800 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058347 ! PKH4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019411 name: PKHD1_human def: "Fibrocystin precursor gene" [UniProtKB:Q8TCZ9] synonym: "FCYT" EXACT [UniProtKB:Q8TCZ9] synonym: "TIGM1" EXACT [UniProtKB:Q8TCZ9] xref: EMBL:AF480064 xref: EMBL:AY074797 xref: EMBL:AY092083 xref: HGNC:HGNC:9016 xref: UniGene:Hs.662050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057919 ! PKHD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019412 name: PLEKHF1_human def: "Pleckstrin homology domain-containing family F member 1 gene" [UniProtKB:Q96S99] synonym: "APPD" EXACT [UniProtKB:Q96S99] synonym: "LAPF" EXACT [UniProtKB:Q96S99] synonym: "ZFYVE15" EXACT [UniProtKB:Q96S99] xref: EMBL:AF434818 xref: EMBL:AK027758 xref: EMBL:AY037145 xref: EMBL:BC002744 xref: HGNC:HGNC:20764 xref: UniGene:Hs.466383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058389 ! PKHF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019413 name: PLEKHG1_human def: "Pleckstrin homology domain-containing family G member 1 gene" [UniProtKB:Q9ULL1] synonym: "KIAA1209" EXACT [UniProtKB:Q9ULL1] xref: EMBL:AB033035 xref: EMBL:AL035086 xref: EMBL:AL450339 xref: HGNC:HGNC:20884 xref: UniGene:Hs.189781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059228 ! PKHG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019414 name: PLEKHG2_human def: "Pleckstrin homology domain-containing family G member 2 gene" [UniProtKB:Q9H7P9] xref: EMBL:AK024429 xref: EMBL:AK026111 xref: EMBL:BC013426 xref: EMBL:BC015174 xref: EMBL:BC075858 xref: HGNC:HGNC:29515 xref: UniGene:Hs.631574 xref: UniGene:Hs.634029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058742 ! PKHG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019415 name: PLEKHG3_human def: "Pleckstrin homology domain-containing family G member 3 gene" [UniProtKB:A1L390] synonym: "KIAA0599" EXACT [UniProtKB:A1L390] xref: EMBL:AB011171 xref: EMBL:AK074169 xref: EMBL:BC004298 xref: EMBL:BC011891 xref: EMBL:BC063554 xref: EMBL:BC073907 xref: EMBL:BC129952 xref: EMBL:BC129953 xref: EMBL:BX248779 xref: HGNC:HGNC:20364 xref: UniGene:Hs.509637 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053712 ! PKHG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019416 name: PLEKHG4_human def: "Puratrophin-1 gene" [UniProtKB:Q58EX7] synonym: "PRTPHN1" EXACT [UniProtKB:Q58EX7] xref: EMBL:AB197663 xref: EMBL:AB197664 xref: EMBL:AK024475 xref: EMBL:AL117435 xref: EMBL:BC054486 xref: EMBL:BC063501 xref: EMBL:BC082974 xref: HGNC:HGNC:24501 xref: UniGene:Hs.188781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056375 ! PKHG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019417 name: PLEKHG5_human def: "Pleckstrin homology domain-containing family G member 5 gene" [UniProtKB:O94827] synonym: "KIAA0720" EXACT [UniProtKB:O94827] xref: EMBL:AB018263 xref: EMBL:AB097001 xref: EMBL:AK131074 xref: EMBL:AL158217 xref: EMBL:AL591866 xref: EMBL:BC015231 xref: EMBL:BC042606 xref: EMBL:CH471130 xref: HGNC:HGNC:29105 xref: UniGene:Hs.284232 xref: UniGene:Hs.619982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054702 ! PKHG5_HUMAN relationship: codes_for CCO:B0056551 ! Q5SY18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019418 name: PLEKHG6_human def: "Pleckstrin homology domain-containing family G member 6 gene" [UniProtKB:Q3KR16] xref: EMBL:AC006057 xref: EMBL:AF289613 xref: EMBL:AK001527 xref: EMBL:AK023741 xref: EMBL:AK095373 xref: EMBL:BC104751 xref: EMBL:BC105961 xref: EMBL:BC109095 xref: EMBL:CH471116 xref: HGNC:HGNC:25562 xref: UniGene:Hs.631660 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056256 ! PKHG6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019419 name: PLEKHG7_human def: "Pleckstrin homology domain-containing family G member 7 gene" [UniProtKB:Q6ZR37] xref: EMBL:AK128530 xref: HGNC:HGNC:33829 xref: UniGene:Hs.591013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057037 ! PKHG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019420 name: PLEKHM1_human def: "Pleckstrin homology domain-containing family M member 1 gene" [UniProtKB:Q9Y4G2] synonym: "KIAA0356" EXACT [UniProtKB:Q9Y4G2] xref: EMBL:AB002354 xref: EMBL:AJ002220 xref: EMBL:AK074103 xref: EMBL:AL389948 xref: EMBL:BC064361 xref: HGNC:HGNC:29017 xref: UniGene:Hs.514242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059361 ! PKHM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019421 name: PLEKHM3_human def: "Pleckstrin homology domain-containing family M member 3 gene" [UniProtKB:Q6ZWE6] synonym: "PLEKHM1L" EXACT [UniProtKB:Q6ZWE6] xref: EMBL:AC083900 xref: EMBL:AC096772 xref: EMBL:AK123204 xref: EMBL:BC020812 xref: HGNC:HGNC:34006 xref: UniGene:Hs.654645 xref: UniGene:Hs.679895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057090 ! PKHM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019422 name: PKNOX1_human def: "Homeobox protein PKNOX1 gene" [UniProtKB:P55347] synonym: "PREP1" EXACT [UniProtKB:P55347] xref: EMBL:AP001748 xref: EMBL:AY142115 xref: EMBL:U68727 xref: EMBL:Y13613 xref: HGNC:HGNC:9022 xref: UniGene:Hs.431043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055535 ! PKNX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019423 name: PKNOX2_human def: "Homeobox protein PKNOX2 gene" [UniProtKB:Q96KN3] synonym: "PREP2" EXACT [UniProtKB:Q96KN3] xref: EMBL:AB065001 xref: EMBL:AJ417081 xref: EMBL:BC045626 xref: EMBL:BX648615 xref: HGNC:HGNC:16714 xref: UniGene:Hs.696454 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058261 ! PKNX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019424 name: PKP1_human def: "Plakophilin-1 gene" [UniProtKB:Q13835] xref: EMBL:X79293 xref: EMBL:Z34974 xref: EMBL:Z73677 xref: EMBL:Z73678 xref: HGNC:HGNC:9023 xref: UniGene:Hs.497350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055947 ! PKP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019425 name: PROKR1_human def: "Prokineticin receptor 1 gene" [UniProtKB:Q8TCW9] synonym: "GPR73" EXACT [UniProtKB:Q8TCW9] synonym: "PKR1" EXACT [UniProtKB:Q8TCW9] xref: EMBL:AB084080 xref: EMBL:AC105054 xref: EMBL:AF506287 xref: EMBL:AY089976 xref: EMBL:BC100960 xref: HGNC:HGNC:4524 xref: UniGene:Hs.258941 xref: UniGene:Hs.683430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057917 ! PKR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019426 name: PROKR2_human def: "Prokineticin receptor 2 gene" [UniProtKB:Q8NFJ6] synonym: "GPR73L1" EXACT [UniProtKB:Q8NFJ6] synonym: "PKR2" EXACT [UniProtKB:Q8NFJ6] xref: EMBL:AB084081 xref: EMBL:AF506288 xref: EMBL:AL121755 xref: EMBL:BC104959 xref: EMBL:BC104961 xref: HGNC:HGNC:15836 xref: UniGene:Hs.375029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057604 ! PKR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019427 name: PLAA_human def: "Phospholipase A-2-activating protein gene" [UniProtKB:Q9Y263] synonym: "PLAP" EXACT [UniProtKB:Q9Y263] xref: EMBL:AF083395 xref: EMBL:AF145020 xref: EMBL:AJ238243 xref: EMBL:AK001642 xref: EMBL:AK002143 xref: EMBL:AK223544 xref: EMBL:AL133608 xref: EMBL:AL356133 xref: EMBL:BC032551 xref: HGNC:HGNC:9043 xref: UniGene:Hs.27182 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059293 ! PLAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019428 name: PLCB3_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 gene" [UniProtKB:Q01970] xref: EMBL:U26425 xref: EMBL:Z16411 xref: EMBL:Z37544 xref: EMBL:Z37545 xref: EMBL:Z37546 xref: EMBL:Z37547 xref: EMBL:Z37548 xref: EMBL:Z37549 xref: EMBL:Z37550 xref: EMBL:Z37551 xref: EMBL:Z37552 xref: EMBL:Z37553 xref: EMBL:Z37554 xref: EMBL:Z37555 xref: EMBL:Z37556 xref: EMBL:Z37557 xref: EMBL:Z37558 xref: EMBL:Z37559 xref: EMBL:Z37560 xref: EMBL:Z37561 xref: EMBL:Z37562 xref: EMBL:Z37564 xref: EMBL:Z37565 xref: EMBL:Z37566 xref: EMBL:Z37567 xref: EMBL:Z37568 xref: EMBL:Z37569 xref: EMBL:Z37570 xref: EMBL:Z37571 xref: EMBL:Z37572 xref: EMBL:Z37573 xref: EMBL:Z37574 xref: HGNC:HGNC:9056 xref: UniGene:Hs.591953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024484 ! PLCB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019429 name: PLCB4_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 gene" [UniProtKB:Q15147] xref: EMBL:AL023805 xref: EMBL:AL031652 xref: EMBL:BC117458 xref: EMBL:L41349 xref: HGNC:HGNC:9059 xref: UniGene:Hs.472101 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026618 ! Q5JYS9_HUMAN relationship: codes_for CCO:B0056047 ! PLCB4_HUMAN relationship: codes_for CCO:B0056511 ! Q5JYT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019430 name: PLCD1_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 gene" [UniProtKB:P51178] xref: EMBL:BC050382 xref: EMBL:CH471055 xref: EMBL:U09117 xref: HGNC:HGNC:9060 xref: UniGene:Hs.80776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055462 ! PLCD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019431 name: PLCD3_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 gene" [UniProtKB:Q8N3E9] synonym: "KIAA1964" EXACT [UniProtKB:Q8N3E9] xref: EMBL:AB075844 xref: EMBL:AK074240 xref: EMBL:AL834392 xref: EMBL:BC010668 xref: EMBL:BC072384 xref: HGNC:HGNC:9061 xref: UniGene:Hs.380094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057455 ! PLCD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019432 name: PLCD4_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 gene" [UniProtKB:Q9BRC7] xref: EMBL:AK223203 xref: EMBL:AY512961 xref: EMBL:BC006355 xref: HGNC:HGNC:9062 xref: UniGene:Hs.632528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058489 ! PLCD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019433 name: PLCE1_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 gene" [UniProtKB:Q9P212] synonym: "KIAA1516" EXACT [UniProtKB:Q9P212] synonym: "PLCE" EXACT [UniProtKB:Q9P212] synonym: "PPLC" EXACT [UniProtKB:Q9P212] xref: EMBL:AB040949 xref: EMBL:AF117948 xref: EMBL:AF170071 xref: EMBL:AF190642 xref: EMBL:AK022543 xref: EMBL:AL139118 xref: EMBL:AL139124 xref: EMBL:AL365510 xref: EMBL:AL389885 xref: EMBL:AY995135 xref: EMBL:CH471066 xref: HGNC:HGNC:17175 xref: UniGene:Hs.655033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056664 ! Q5VWL4_HUMAN relationship: codes_for CCO:B0059048 ! PLCE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019434 name: PLCG2_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 gene" [UniProtKB:P16885] xref: EMBL:AB208914 xref: EMBL:AC092142 xref: EMBL:AC098966 xref: EMBL:AC099524 xref: EMBL:AY364256 xref: EMBL:BC007565 xref: EMBL:BC011772 xref: EMBL:BC014561 xref: EMBL:BC018646 xref: EMBL:M37238 xref: EMBL:X14034 xref: HGNC:HGNC:9066 xref: UniGene:Hs.413111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055061 ! PLCG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019435 name: PLCH1_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1 gene" [UniProtKB:Q4KWH8] synonym: "KIAA1069" EXACT [UniProtKB:Q4KWH8] synonym: "PLCL3" EXACT [UniProtKB:Q4KWH8] xref: EMBL:AB028992 xref: EMBL:AK022610 xref: EMBL:AY691170 xref: EMBL:AY691171 xref: EMBL:BC043248 xref: EMBL:BC113950 xref: EMBL:CR749869 xref: HGNC:HGNC:29185 xref: UniGene:Hs.567423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056320 ! PLCH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019436 name: PLCH2_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2 gene" [UniProtKB:O75038] synonym: "KIAA0450" EXACT [UniProtKB:O75038] synonym: "PLCL4" EXACT [UniProtKB:O75038] xref: EMBL:AB007919 xref: EMBL:AK074149 xref: EMBL:AK122591 xref: EMBL:BC019679 xref: EMBL:BC043358 xref: EMBL:BC050037 xref: EMBL:BC128207 xref: EMBL:DQ176850 xref: HGNC:HGNC:29037 xref: UniGene:Hs.170156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054596 ! PLCH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019437 name: PLCL1_human def: "Inactive phospholipase C-like protein 1 gene" [UniProtKB:Q15111] xref: EMBL:AC011997 xref: EMBL:AC013478 xref: EMBL:AC020719 xref: EMBL:BC101531 xref: EMBL:BC111985 xref: EMBL:BX537442 xref: EMBL:D42108 xref: HGNC:HGNC:9063 xref: UniGene:Hs.153322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056044 ! PLCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019438 name: PLCL2_human def: "Inactive phospholipase C-like protein 2 gene" [UniProtKB:Q9UPR0] synonym: "KIAA1092" EXACT [UniProtKB:Q9UPR0] synonym: "PLCE2" EXACT [UniProtKB:Q9UPR0] xref: EMBL:AB029015 xref: EMBL:AK023546 xref: EMBL:AL117515 xref: EMBL:BC036392 xref: HGNC:HGNC:9064 xref: UniGene:Hs.202010 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059265 ! PLCL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019439 name: PLCXD1_human def: "Phosphatidylinositol-specific phospholipase C X domain-containing protein 1 gene" [UniProtKB:Q9NUJ7] xref: EMBL:AK002185 xref: EMBL:BC005028 xref: EMBL:BX537334 xref: EMBL:CH471225 xref: HGNC:HGNC:23148 xref: UniGene:Hs.522568 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058927 ! PLCX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019440 name: PLCXD2_human def: "Phosphatidylinositol-specific phospholipase C X domain-containing protein 2 gene" [UniProtKB:Q0VAA5] xref: EMBL:AK056141 xref: EMBL:BC121155 xref: EMBL:BC121156 xref: HGNC:HGNC:26462 xref: UniGene:Hs.668529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055818 ! PLCX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019441 name: PLCXD3_human def: "Phosphatidylinositol-specific phospholipase C X domain-containing protein 3 gene" [UniProtKB:Q63HM9] xref: EMBL:BX648329 xref: HGNC:HGNC:31822 xref: UniGene:Hs.145404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056688 ! PLCX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019442 name: PLEK2_human def: "Pleckstrin-2 gene" [UniProtKB:Q9NYT0] xref: EMBL:AF228603 xref: EMBL:BC001226 xref: EMBL:BC008056 xref: HGNC:HGNC:19238 xref: UniGene:Hs.170473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058972 ! PLEK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019443 name: PLEK_human def: "Pleckstrin gene" [UniProtKB:P08567] synonym: "P47" EXACT [UniProtKB:P08567] xref: EMBL:AC015969 xref: EMBL:BC018549 xref: EMBL:CR542079 xref: EMBL:X07743 xref: HGNC:HGNC:9070 xref: UniGene:Hs.468840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054927 ! PLEK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019444 name: PLG_human def: "Plasminogen precursor gene" [UniProtKB:P00747] xref: EMBL:AL109933 xref: EMBL:AY192161 xref: EMBL:BC060513 xref: EMBL:K02922 xref: EMBL:M33272 xref: EMBL:M33274 xref: EMBL:M33275 xref: EMBL:M33278 xref: EMBL:M33279 xref: EMBL:M33280 xref: EMBL:M33282 xref: EMBL:M33283 xref: EMBL:M33284 xref: EMBL:M33285 xref: EMBL:M33286 xref: EMBL:M33287 xref: EMBL:M33288 xref: EMBL:M33289 xref: EMBL:M33290 xref: EMBL:M34272 xref: EMBL:M34273 xref: EMBL:M34275 xref: EMBL:M34276 xref: EMBL:M74220 xref: EMBL:X05199 xref: HGNC:HGNC:9071 xref: UniGene:Hs.143436 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054826 ! PLMN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019445 name: PLP2_human def: "Proteolipid protein 2 gene" [UniProtKB:Q04941] synonym: "A4" EXACT [UniProtKB:Q04941] xref: EMBL:BC109066 xref: EMBL:L09604 xref: EMBL:U93305 xref: HGNC:HGNC:9087 xref: UniGene:Hs.77422 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055740 ! PLP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019446 name: PLXNA1_human def: "Plexin-A1 precursor gene" [UniProtKB:Q9UIW2] synonym: "NOV" EXACT [UniProtKB:Q9UIW2] synonym: "PLXN1" EXACT [UniProtKB:Q9UIW2] xref: EMBL:AC011199 xref: EMBL:AK128612 xref: EMBL:X87832 xref: HGNC:HGNC:9099 xref: UniGene:Hs.432329 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059167 ! PLXA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019447 name: PLXNA2_human def: "Plexin-A2 precursor gene" [UniProtKB:O75051] synonym: "KIAA0463" EXACT [UniProtKB:O75051] synonym: "OCT" EXACT [UniProtKB:O75051] synonym: "PLXN2" EXACT [UniProtKB:O75051] synonym: "UNQ209/PRO235" EXACT [UniProtKB:O75051] xref: EMBL:AB007932 xref: EMBL:AL356275 xref: EMBL:AL590138 xref: EMBL:AY358496 xref: EMBL:BC006193 xref: EMBL:BC009343 xref: EMBL:BC032125 xref: EMBL:BC094835 xref: EMBL:BC132676 xref: EMBL:BC136530 xref: EMBL:X87831 xref: HGNC:HGNC:9100 xref: UniGene:Hs.497626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054599 ! PLXA2_HUMAN relationship: codes_for CCO:B0057477 ! Q8N5M2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019448 name: PLXNA3_human def: "Plexin-A3 precursor gene" [UniProtKB:P51805] synonym: "PLXN4" EXACT [UniProtKB:P51805] synonym: "SEX" EXACT [UniProtKB:P51805] xref: EMBL:BX936365 xref: EMBL:X87852 xref: HGNC:HGNC:9101 xref: UniGene:Hs.632839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055480 ! PLXA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019449 name: PLXNA4_human def: "Plexin-A4 precursor gene" [UniProtKB:Q9HCM2] synonym: "KIAA1550" EXACT [UniProtKB:Q9HCM2] synonym: "PLXNA4A" EXACT [UniProtKB:Q9HCM2] synonym: "PLXNA4B" EXACT [UniProtKB:Q9HCM2] synonym: "UNQ2820/PRO34003" EXACT [UniProtKB:Q9HCM2] xref: EMBL:AB046770 xref: EMBL:AC009364 xref: EMBL:AC009785 xref: EMBL:AC018643 xref: EMBL:AK095606 xref: EMBL:AK123428 xref: EMBL:AL137352 xref: EMBL:AL834504 xref: EMBL:AY358850 xref: EMBL:BC028744 xref: HGNC:HGNC:9102 xref: UniGene:Hs.511454 xref: UniGene:Hs.675491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058812 ! PLXA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019450 name: PLXNB1_human def: "Plexin-B1 precursor gene" [UniProtKB:O43157] synonym: "KIAA0407" EXACT [UniProtKB:O43157] synonym: "PLXN5" EXACT [UniProtKB:O43157] synonym: "SEP" EXACT [UniProtKB:O43157] xref: EMBL:AB007867 xref: EMBL:AJ011414 xref: EMBL:AJ011415 xref: EMBL:X87904 xref: HGNC:HGNC:9103 xref: UniGene:Hs.476209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054451 ! PLXB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019451 name: PLXNC1_human def: "Plexin-C1 precursor gene" [UniProtKB:O60486] synonym: "VESPR" EXACT [UniProtKB:O60486] xref: EMBL:AB208934 xref: EMBL:AF030339 xref: HGNC:HGNC:9106 xref: UniGene:Hs.584845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054561 ! PLXC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019452 name: PLXND1_human def: "Plexin-D1 precursor gene" [UniProtKB:Q9Y4D7] synonym: "KIAA0620" EXACT [UniProtKB:Q9Y4D7] xref: EMBL:AB014520 xref: EMBL:AY116661 xref: EMBL:BC003526 xref: EMBL:BC011848 xref: HGNC:HGNC:9107 xref: UniGene:Hs.301685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059359 ! PLXD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019453 name: PMS2L3_human def: "Postmeiotic segregation increased 2-like protein 3 gene" [UniProtKB:Q13401] synonym: "PMS2L9" EXACT [UniProtKB:Q13401] synonym: "PMS5" EXACT [UniProtKB:Q13401] synonym: "PMSR3" EXACT [UniProtKB:Q13401] xref: EMBL:AC018720 xref: EMBL:BC101598 xref: EMBL:CH471220 xref: EMBL:U38979 xref: HGNC:HGNC:9128 xref: UniGene:Hs.436034 xref: UniGene:Hs.659871 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053828 ! A6NG70_HUMAN relationship: codes_for CCO:B0055906 ! PM2L3_HUMAN relationship: codes_for CCO:B0056264 ! Q3MJ29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019454 name: PMS2L11_human def: "Postmeiotic segregation increased 2-like protein 11 gene" [UniProtKB:Q13670] synonym: "PMSR6" EXACT [UniProtKB:Q13670] xref: EMBL:U38980 xref: HGNC:HGNC:9125 xref: UniGene:Hs.113940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055938 ! PM2LB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019455 name: PMS2L16_human def: "Postmeiotic segregation increased 2-like protein 16 gene" [UniProtKB:O95746] xref: EMBL:AB017007 xref: UniGene:Hs.292996 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054790 ! PM2LG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019456 name: PMEPA1_human def: "Transmembrane prostate androgen-induced protein gene" [UniProtKB:Q969W9] synonym: "STAG1" EXACT [UniProtKB:Q969W9] synonym: "TMEPAI" EXACT [UniProtKB:Q969W9] xref: EMBL:AF224278 xref: EMBL:AF305426 xref: EMBL:AF305616 xref: EMBL:AL035541 xref: EMBL:AL121913 xref: EMBL:BC015918 xref: HGNC:HGNC:14107 xref: UniGene:Hs.517155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058144 ! PMEPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019457 name: PNKP_human def: "Bifunctional polynucleotide phosphatase/kinase gene" [UniProtKB:Q96T60] xref: EMBL:AC018766 xref: EMBL:AF120499 xref: EMBL:AF125807 xref: EMBL:AF126486 xref: EMBL:AF354258 xref: EMBL:AY133033 xref: EMBL:BC033822 xref: HGNC:HGNC:9154 xref: UniGene:Hs.78016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058402 ! PNKP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019458 name: PNOC_human def: "Nociceptin precursor gene" [UniProtKB:Q13519] synonym: "OFQ" EXACT [UniProtKB:Q13519] xref: EMBL:BC034758 xref: EMBL:U48263 xref: EMBL:X97367 xref: EMBL:X97368 xref: EMBL:X97370 xref: HGNC:HGNC:9163 xref: UniGene:Hs.88218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055923 ! PNOC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019459 name: PNRC1_human def: "Proline-rich nuclear receptor coactivator 1 gene" [UniProtKB:Q12796] synonym: "PROL2" EXACT [UniProtKB:Q12796] xref: EMBL:AL353135 xref: EMBL:BC018112 xref: EMBL:U03105 xref: HGNC:HGNC:17278 xref: UniGene:Hs.75969 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055841 ! PNRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019460 name: PNRC2_human def: "Proline-rich nuclear receptor coactivator 2 gene" [UniProtKB:Q9NPJ4] synonym: "HSPC208" EXACT [UniProtKB:Q9NPJ4] xref: EMBL:AF151042 xref: EMBL:AF374386 xref: EMBL:AK000319 xref: EMBL:AL590609 xref: EMBL:BC001959 xref: EMBL:BC078177 xref: EMBL:BC085018 xref: HGNC:HGNC:23158 xref: UniGene:Hs.512636 xref: UniGene:Hs.644217 xref: UniGene:Hs.7862 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058855 ! PNRC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019461 name: POU2F2_human def: "POU domain, class 2, transcription factor 2 gene" [UniProtKB:P09086] synonym: "OCT2" EXACT [UniProtKB:P09086] synonym: "OTF2" EXACT [UniProtKB:P09086] xref: EMBL:BC006101 xref: EMBL:BT007438 xref: EMBL:M36542 xref: EMBL:M36653 xref: EMBL:M36718 xref: EMBL:X13809 xref: EMBL:X13810 xref: EMBL:X53468 xref: EMBL:X53469 xref: EMBL:X81030 xref: HGNC:HGNC:9213 xref: UniGene:Hs.654420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054940 ! PO2F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019462 name: POU4F2_human def: "POU domain, class 4, transcription factor 2 gene" [UniProtKB:Q12837] synonym: "BRN3B" EXACT [UniProtKB:Q12837] xref: EMBL:L20434 xref: EMBL:U06233 xref: EMBL:X71488 xref: HGNC:HGNC:9219 xref: UniGene:Hs.266 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055847 ! PO4F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019463 name: POU6F1_human def: "POU domain, class 6, transcription factor 1 gene" [UniProtKB:Q14863] synonym: "BRN5" EXACT [UniProtKB:Q14863] synonym: "MPOU" EXACT [UniProtKB:Q14863] synonym: "TCFB1" EXACT [UniProtKB:Q14863] xref: EMBL:BC074765 xref: EMBL:L14482 xref: EMBL:Z21966 xref: EMBL:Z21967 xref: HGNC:HGNC:9224 xref: UniGene:Hs.594817 xref: UniGene:Hs.632482 xref: UniGene:Hs.646545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056019 ! PO6F1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019464 name: POU6F2_human def: "POU domain, class 6, transcription factor 2 gene" [UniProtKB:P78424] synonym: "RPF1" EXACT [UniProtKB:P78424] xref: EMBL:AC005483 xref: EMBL:AC073345 xref: EMBL:AC092174 xref: EMBL:U91934 xref: EMBL:U91935 xref: HGNC:HGNC:21694 xref: UniGene:Hs.137106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055646 ! PO6F2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019465 name: PODXL_human def: "Podocalyxin-like protein 1 precursor gene" [UniProtKB:O00592] synonym: "PCLP" EXACT [UniProtKB:O00592] synonym: "PCLP1" EXACT [UniProtKB:O00592] xref: EMBL:U97519 xref: HGNC:HGNC:9171 xref: UniGene:Hs.16426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054336 ! PODXL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019466 name: POGK_human def: "Pogo transposable element with KRAB domain gene" [UniProtKB:Q9P215] synonym: "KIAA1513" EXACT [UniProtKB:Q9P215] synonym: "LST003" EXACT [UniProtKB:Q9P215] synonym: "SLTP003" EXACT [UniProtKB:Q9P215] xref: EMBL:AB040946 xref: EMBL:AF111706 xref: EMBL:AL008639 xref: HGNC:HGNC:18800 xref: UniGene:Hs.432752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056635 ! Q5TIJ2_HUMAN relationship: codes_for CCO:B0059049 ! POGK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019467 name: POGZ_human def: "Pogo transposable element with ZNF domain gene" [UniProtKB:Q7Z3K3] synonym: "KIAA0461" EXACT [UniProtKB:Q7Z3K3] synonym: "Nbla00003" EXACT [UniProtKB:Q7Z3K3] xref: EMBL:AB007930 xref: EMBL:AB037911 xref: EMBL:AB075477 xref: EMBL:AJ242979 xref: EMBL:AL589764 xref: EMBL:BC057773 xref: EMBL:BX537838 xref: EMBL:CH471121 xref: HGNC:HGNC:18801 xref: UniGene:Hs.591471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024266 ! POGZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019468 name: ERVK6_human def: "HERV-K_7p22.1 provirus ancestral Pol protein gene" [UniProtKB:Q9BXR3] xref: EMBL:AC072054 xref: EMBL:AC112702 xref: EMBL:AF074086 xref: EMBL:AF080233 xref: EMBL:AF164614 xref: EMBL:AF298587 xref: EMBL:AF298588 xref: EMBL:U87592 xref: EMBL:Y17832 xref: EMBL:Y17833 xref: EMBL:Y17834 xref: HGNC:HGNC:13915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058563 ! POK2_HUMAN relationship: codes_for CCO:B0059287 ! POK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019469 name: POLI_human def: "DNA polymerase iota gene" [UniProtKB:Q9UNA4] synonym: "RAD30B" EXACT [UniProtKB:Q9UNA4] xref: EMBL:AF140501 xref: EMBL:AF245438 xref: EMBL:AL136670 xref: EMBL:AY094607 xref: EMBL:BC032662 xref: HGNC:HGNC:9182 xref: UniGene:Hs.438533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059249 ! POLI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019470 name: PORCN_human def: "Probable protein-cysteine N-palmitoyltransferase porcupine gene" [UniProtKB:Q9H237] synonym: "MG61" EXACT [UniProtKB:Q9H237] synonym: "PORC" EXACT [UniProtKB:Q9H237] synonym: "PPN" EXACT [UniProtKB:Q9H237] xref: EMBL:AF317058 xref: EMBL:AF317059 xref: EMBL:AF317060 xref: EMBL:AF317061 xref: EMBL:BC019080 xref: EMBL:L08239 xref: HGNC:HGNC:17652 xref: UniGene:Hs.386453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058674 ! PORCN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019471 name: PPP1R14A_human def: "Protein phosphatase 1 regulatory subunit 14A gene" [UniProtKB:Q96A00] synonym: "CPI17" EXACT [UniProtKB:Q96A00] synonym: "PPP1INL" EXACT [UniProtKB:Q96A00] xref: EMBL:AB056508 xref: EMBL:AB056509 xref: EMBL:AF123763 xref: EMBL:AY050668 xref: EMBL:AY050670 xref: EMBL:BC021089 xref: HGNC:HGNC:14871 xref: UniGene:Hs.631569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058145 ! PP14A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019472 name: PPP1R14B_human def: "Protein phosphatase 1 regulatory subunit 14B gene" [UniProtKB:Q96C90] synonym: "PLCB3N" EXACT [UniProtKB:Q96C90] synonym: "PNG" EXACT [UniProtKB:Q96C90] xref: EMBL:BC014522 xref: EMBL:BC094817 xref: EMBL:BT009914 xref: HGNC:HGNC:9057 xref: UniGene:Hs.523760 xref: UniGene:Hs.596713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058179 ! PP14B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019473 name: PPP1R14C_human def: "Protein phosphatase 1 regulatory subunit 14C gene" [UniProtKB:Q8TAE6] synonym: "KEPI" EXACT [UniProtKB:Q8TAE6] xref: EMBL:AF308297 xref: EMBL:AF407165 xref: EMBL:AF407166 xref: EMBL:AL096708 xref: EMBL:AL355497 xref: EMBL:BC015773 xref: HGNC:HGNC:14952 xref: UniGene:Hs.486798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057886 ! PP14C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019474 name: PPP1R14D_human def: "Protein phosphatase 1 regulatory subunit 14D gene" [UniProtKB:Q9NXH3] synonym: "GBPI" EXACT [UniProtKB:Q9NXH3] xref: EMBL:AK000258 xref: EMBL:AY050671 xref: EMBL:BC096716 xref: EMBL:BC098124 xref: HGNC:HGNC:14953 xref: UniGene:Hs.192927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058953 ! PP14D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019475 name: PPP1R16B_human def: "Protein phosphatase 1 regulatory inhibitor subunit 16B gene" [UniProtKB:Q96T49] synonym: "ANKRD4" EXACT [UniProtKB:Q96T49] synonym: "KIAA0823" EXACT [UniProtKB:Q96T49] xref: EMBL:AB020630 xref: EMBL:AF362910 xref: EMBL:AL031657 xref: EMBL:AL121889 xref: HGNC:HGNC:15850 xref: UniGene:Hs.45719 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058401 ! PP16B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019476 name: PPP1R8_human def: "Nuclear inhibitor of protein phosphatase 1 gene" [UniProtKB:Q12972] synonym: "ARD1" EXACT [UniProtKB:Q12972] synonym: "NIPP1" EXACT [UniProtKB:Q12972] xref: EMBL:AF061958 xref: EMBL:AF061959 xref: EMBL:AF064751 xref: EMBL:AF064752 xref: EMBL:AF064753 xref: EMBL:AF064754 xref: EMBL:AF064755 xref: EMBL:AF064756 xref: EMBL:AF064757 xref: EMBL:AF126488 xref: EMBL:AL020997 xref: EMBL:AL109927 xref: EMBL:BC001597 xref: EMBL:BC013360 xref: EMBL:U14575 xref: HGNC:HGNC:9296 xref: UniGene:Hs.533474 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055860 ! PP1R8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019477 name: PPP3CC_human def: "Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform gene" [UniProtKB:P48454] synonym: "CALNA3" EXACT [UniProtKB:P48454] synonym: "CNA3" EXACT [UniProtKB:P48454] xref: EMBL:AY007249 xref: EMBL:CH471080 xref: EMBL:S46622 xref: HGNC:HGNC:9316 xref: UniGene:Hs.655661 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016299 ! PP2BC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019478 name: PPP4R1_human def: "Serine/threonine-protein phosphatase 4 regulatory subunit 1 gene" [UniProtKB:Q8TF05] synonym: "MEG1" EXACT [UniProtKB:Q8TF05] synonym: "PP4R1" EXACT [UniProtKB:Q8TF05] xref: EMBL:AF100744 xref: EMBL:AF111106 xref: EMBL:AF200478 xref: EMBL:BC060829 xref: EMBL:U79267 xref: HGNC:HGNC:9320 xref: UniGene:Hs.464595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057959 ! PP4R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019479 name: PPARA_human def: "Peroxisome proliferator-activated receptor alpha gene" [UniProtKB:Q07869] synonym: "NR1C1" EXACT [UniProtKB:Q07869] synonym: "PPAR" EXACT [UniProtKB:Q07869] xref: EMBL:AL049856 xref: EMBL:AL078611 xref: EMBL:AY206718 xref: EMBL:CR456547 xref: EMBL:L02932 xref: EMBL:S74349 xref: EMBL:Y07619 xref: HGNC:HGNC:9232 xref: UniGene:Hs.103110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054176 ! B0QYX1_HUMAN relationship: codes_for CCO:B0054177 ! B0QYX2_HUMAN relationship: codes_for CCO:B0055786 ! PPARA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019480 name: PPARD_human def: "Peroxisome proliferator-activated receptor delta gene" [UniProtKB:Q03181] synonym: "NR1C2" EXACT [UniProtKB:Q03181] synonym: "PPARB" EXACT [UniProtKB:Q03181] xref: EMBL:AB099507 xref: EMBL:AF246299 xref: EMBL:AF246300 xref: EMBL:AF246301 xref: EMBL:AF246302 xref: EMBL:AF246303 xref: EMBL:AL022721 xref: EMBL:AY442342 xref: EMBL:BC002715 xref: EMBL:BC007578 xref: EMBL:L07592 xref: HGNC:HGNC:9235 xref: UniGene:Hs.696032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055722 ! PPARD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019481 name: PPIE_human def: "Peptidyl-prolyl cis-trans isomerase E gene" [UniProtKB:Q9UNP9] synonym: "CYP33" EXACT [UniProtKB:Q9UNP9] xref: EMBL:AF042385 xref: EMBL:AF042386 xref: EMBL:AF104012 xref: EMBL:AF104013 xref: EMBL:AL035404 xref: EMBL:AL049824 xref: EMBL:BC004898 xref: EMBL:BC008451 xref: EMBL:BC107736 xref: HGNC:HGNC:9258 xref: UniGene:Hs.700626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059255 ! PPIE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019482 name: PPP1R1A_human def: "Protein phosphatase 1 regulatory subunit 1A gene" [UniProtKB:Q13522] synonym: "IPP1" EXACT [UniProtKB:Q13522] xref: EMBL:AY063766 xref: EMBL:BC022470 xref: EMBL:CR457003 xref: EMBL:U48707 xref: HGNC:HGNC:9286 xref: UniGene:Hs.505662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055924 ! PPR1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019483 name: PPP1R1B_human def: "Protein phosphatase 1 regulatory subunit 1B gene" [UniProtKB:Q9UD71] synonym: "DARPP32" EXACT [UniProtKB:Q9UD71] xref: EMBL:AF435972 xref: EMBL:AF435973 xref: EMBL:AF435974 xref: EMBL:AF435975 xref: EMBL:AF464196 xref: EMBL:AK024593 xref: EMBL:AY070271 xref: EMBL:BC001519 xref: EMBL:BT007076 xref: HGNC:HGNC:9287 xref: UniGene:Hs.286192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059099 ! PPR1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019484 name: PPP1R1C_human def: "Protein phosphatase 1 regulatory subunit 1C gene" [UniProtKB:Q8WVI7] xref: EMBL:AF494535 xref: EMBL:BC017943 xref: EMBL:BX647581 xref: HGNC:HGNC:14940 xref: UniGene:Hs.10941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057993 ! PPR1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019485 name: PPP1R15B_human def: "Protein phosphatase 1 regulatory subunit 15B gene" [UniProtKB:Q5SWA1] xref: EMBL:AK027650 xref: EMBL:AK222877 xref: EMBL:AL606489 xref: EMBL:AL833746 xref: EMBL:BC065280 xref: HGNC:HGNC:14951 xref: UniGene:Hs.304376 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056548 ! PR15B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019486 name: PRAM1_human def: "PML-RARA-regulated adapter molecule 1 gene" [UniProtKB:Q96QH2] xref: EMBL:AJ272324 xref: EMBL:BC028012 xref: HGNC:HGNC:30091 xref: UniGene:Hs.465812 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058353 ! PRAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019487 name: PRDM10_human def: "PR domain zinc finger protein 10 gene" [UniProtKB:Q9NQV6] synonym: "KIAA1231" EXACT [UniProtKB:Q9NQV6] synonym: "PFM7" EXACT [UniProtKB:Q9NQV6] xref: EMBL:AB033057 xref: EMBL:AF275817 xref: EMBL:AF503171 xref: EMBL:AP003326 xref: EMBL:AP003327 xref: HGNC:HGNC:13995 xref: UniGene:Hs.275086 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058873 ! PRD10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019488 name: PRDM12_human def: "PR domain zinc finger protein 12 gene" [UniProtKB:Q9H4Q4] synonym: "PFM9" EXACT [UniProtKB:Q9H4Q4] xref: EMBL:AY004252 xref: HGNC:HGNC:13997 xref: UniGene:Hs.495311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058719 ! PRD12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019489 name: PRDM13_human def: "PR domain zinc finger protein 13 gene" [UniProtKB:Q9H4Q3] synonym: "PFM10" EXACT [UniProtKB:Q9H4Q3] xref: EMBL:AL035087 xref: EMBL:AL137784 xref: EMBL:AY004253 xref: HGNC:HGNC:13998 xref: UniGene:Hs.287386 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058718 ! PRD13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019490 name: PRDM14_human def: "PR domain zinc finger protein 14 gene" [UniProtKB:Q9GZV8] xref: EMBL:AF319458 xref: EMBL:AK022595 xref: EMBL:BC052311 xref: HGNC:HGNC:14001 xref: UniGene:Hs.287532 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058639 ! PRD14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019491 name: PRDM15_human def: "PR domain zinc finger protein 15 gene" [UniProtKB:P57071] synonym: "C21orf83" EXACT [UniProtKB:P57071] synonym: "ZNF298" EXACT [UniProtKB:P57071] xref: EMBL:AF276513 xref: EMBL:AF426259 xref: EMBL:AF426260 xref: EMBL:AP001745 xref: EMBL:AY063456 xref: EMBL:AY078498 xref: HGNC:HGNC:13999 xref: UniGene:Hs.473893 xref: UniGene:Hs.695402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055556 ! PRD15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019492 name: PRDM16_human def: "PR domain zinc finger protein 16 gene" [UniProtKB:Q9HAZ2] synonym: "KIAA1675" EXACT [UniProtKB:Q9HAZ2] synonym: "MEL1" EXACT [UniProtKB:Q9HAZ2] synonym: "PFM13" EXACT [UniProtKB:Q9HAZ2] xref: EMBL:AB051462 xref: EMBL:AB078876 xref: EMBL:AF294278 xref: EMBL:AL008733 xref: EMBL:AL354743 xref: EMBL:AL512383 xref: EMBL:AL590438 xref: HGNC:HGNC:14000 xref: UniGene:Hs.99500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058772 ! PRD16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019493 name: PRDM1_human def: "PR domain zinc finger protein 1 gene" [UniProtKB:O75626] synonym: "BLIMP1" EXACT [UniProtKB:O75626] xref: EMBL:AF084199 xref: EMBL:AY198414 xref: HGNC:HGNC:9346 xref: UniGene:Hs.436023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054658 ! PRDM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019494 name: PRDM2_human def: "PR domain zinc finger protein 2 gene" [UniProtKB:Q13029] synonym: "KMT8" EXACT [UniProtKB:Q13029] synonym: "RIZ" EXACT [UniProtKB:Q13029] xref: EMBL:AL031277 xref: EMBL:AL359771 xref: EMBL:AL583942 xref: EMBL:D45132 xref: EMBL:U17838 xref: EMBL:U23736 xref: HGNC:HGNC:9347 xref: UniGene:Hs.371823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054072 ! A8MW16_HUMAN relationship: codes_for CCO:B0054084 ! A8MWY4_HUMAN relationship: codes_for CCO:B0055868 ! PRDM2_HUMAN relationship: codes_for CCO:B0056627 ! Q5THJ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019495 name: PRDM4_human def: "PR domain zinc finger protein 4 gene" [UniProtKB:Q9UKN5] synonym: "PFM1" EXACT [UniProtKB:Q9UKN5] xref: EMBL:AF144757 xref: EMBL:AL133083 xref: EMBL:BC035581 xref: HGNC:HGNC:9348 xref: UniGene:Hs.506655 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059197 ! PRDM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019496 name: PRDM5_human def: "PR domain zinc finger protein 5 gene" [UniProtKB:Q9NQX1] synonym: "PFM2" EXACT [UniProtKB:Q9NQX1] xref: EMBL:AC025741 xref: EMBL:AC104068 xref: EMBL:AC104795 xref: EMBL:AF272897 xref: EMBL:AK056352 xref: EMBL:BC066942 xref: EMBL:BC121037 xref: HGNC:HGNC:9349 xref: UniGene:Hs.660435 xref: UniGene:Hs.669312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058879 ! PRDM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019497 name: PRDM6_human def: "PR domain zinc finger protein 6 gene" [UniProtKB:Q9NQX0] synonym: "PFM3" EXACT [UniProtKB:Q9NQX0] xref: EMBL:AF272898 xref: EMBL:AF272899 xref: HGNC:HGNC:9350 xref: UniGene:Hs.135118 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058878 ! PRDM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019498 name: PRDM7_human def: "PR domain zinc finger protein 7 gene" [UniProtKB:Q9NQW5] synonym: "PFM4" EXACT [UniProtKB:Q9NQW5] xref: EMBL:AF274347 xref: EMBL:AF274348 xref: HGNC:HGNC:9351 xref: UniGene:Hs.406695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058876 ! PRDM7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019499 name: PRDM8_human def: "PR domain zinc finger protein 8 gene" [UniProtKB:Q9NQV8] synonym: "PFM5" EXACT [UniProtKB:Q9NQV8] xref: EMBL:AF275815 xref: EMBL:AK292137 xref: EMBL:BC071584 xref: EMBL:CH471057 xref: HGNC:HGNC:13993 xref: UniGene:Hs.373642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058875 ! PRDM8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019500 name: PRDM9_human def: "PR domain zinc finger protein 9 gene" [UniProtKB:Q9NQV7] synonym: "PFM6" EXACT [UniProtKB:Q9NQV7] xref: EMBL:AC025451 xref: EMBL:AF275816 xref: EMBL:DQ388610 xref: HGNC:HGNC:13994 xref: UniGene:Hs.283096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058874 ! PRDM9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019501 name: PRDX1_human def: "Peroxiredoxin-1 gene" [UniProtKB:Q06830] synonym: "PAGA" EXACT [UniProtKB:Q06830] synonym: "PAGB" EXACT [UniProtKB:Q06830] synonym: "TDPX2" EXACT [UniProtKB:Q06830] xref: EMBL:AL451136 xref: EMBL:BC007063 xref: EMBL:BC021683 xref: EMBL:BT019740 xref: EMBL:CR407652 xref: EMBL:DQ297142 xref: EMBL:L19184 xref: EMBL:X67951 xref: HGNC:HGNC:9352 xref: UniGene:Hs.180909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055775 ! PRDX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019502 name: PRDX2_human def: "Peroxiredoxin-2 gene" [UniProtKB:P32119] synonym: "NKEFB" EXACT [UniProtKB:P32119] synonym: "TDPX1" EXACT [UniProtKB:P32119] xref: EMBL:BC000452 xref: EMBL:BC003022 xref: EMBL:BC039428 xref: EMBL:CR450356 xref: EMBL:CR541789 xref: EMBL:DQ231563 xref: EMBL:L19185 xref: EMBL:X82321 xref: EMBL:Z22548 xref: HGNC:HGNC:9353 xref: UniGene:Hs.432121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055249 ! PRDX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019503 name: PRDX3_human def: "Thioredoxin-dependent peroxide reductase, mitochondrial precursor gene" [UniProtKB:P30048] synonym: "AOP1" EXACT [UniProtKB:P30048] xref: EMBL:AL355861 xref: EMBL:BC002685 xref: EMBL:BC007062 xref: EMBL:BC008435 xref: EMBL:BC009601 xref: EMBL:BC021691 xref: EMBL:BC022373 xref: EMBL:BC059169 xref: EMBL:BC111397 xref: EMBL:BT020007 xref: EMBL:CR450344 xref: EMBL:D49396 xref: EMBL:DQ298752 xref: HGNC:HGNC:9354 xref: UniGene:Hs.523302 xref: UniGene:Hs.604267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055216 ! PRDX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019504 name: PRDX4_human def: "Peroxiredoxin-4 gene" [UniProtKB:Q13162] xref: EMBL:BC003609 xref: EMBL:BC007107 xref: EMBL:BC016770 xref: EMBL:CR541668 xref: EMBL:CR541705 xref: EMBL:U25182 xref: HGNC:HGNC:17169 xref: UniGene:Hs.83383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055882 ! PRDX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019505 name: PREB_human def: "Prolactin regulatory element-binding protein gene" [UniProtKB:Q9HCU5] synonym: "SEC12" EXACT [UniProtKB:Q9HCU5] xref: EMBL:AF203687 xref: EMBL:AF226684 xref: EMBL:AF227166 xref: EMBL:AK023064 xref: EMBL:BC002765 xref: EMBL:BC012890 xref: EMBL:BC016472 xref: EMBL:BC041032 xref: HGNC:HGNC:9356 xref: UniGene:Hs.279784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058819 ! PREB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019506 name: PRG3_human def: "Proteoglycan 3 precursor gene" [UniProtKB:Q9Y2Y8] synonym: "MBPH" EXACT [UniProtKB:Q9Y2Y8] synonym: "UNQ486/PRO1002" EXACT [UniProtKB:Q9Y2Y8] xref: EMBL:AF132209 xref: EMBL:AF304354 xref: EMBL:AY358930 xref: EMBL:BC069126 xref: EMBL:BC101613 xref: EMBL:BC113411 xref: HGNC:HGNC:9363 xref: UniGene:Hs.251386 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059325 ! PRG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019507 name: PRG4_human def: "Proteoglycan 4 precursor gene" [UniProtKB:Q92954] synonym: "MSF" EXACT [UniProtKB:Q92954] synonym: "SZP" EXACT [UniProtKB:Q92954] xref: EMBL:AK131434 xref: EMBL:AL133553 xref: EMBL:AY653037 xref: EMBL:AY653038 xref: EMBL:U70136 xref: HGNC:HGNC:9364 xref: UniGene:Hs.647723 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058115 ! PRG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019508 name: PPARGC1B_human def: "Peroxisome proliferator-activated receptor gamma coactivator 1-beta gene" [UniProtKB:Q86YN6] synonym: "PERC" EXACT [UniProtKB:Q86YN6] synonym: "PGC1" EXACT [UniProtKB:Q86YN6] synonym: "PGC1B" EXACT [UniProtKB:Q86YN6] synonym: "PPARGC1" EXACT [UniProtKB:Q86YN6] xref: EMBL:AF468496 xref: EMBL:AF468497 xref: EMBL:AK095391 xref: EMBL:AY188947 xref: EMBL:AY188948 xref: EMBL:AY188949 xref: EMBL:AY188950 xref: EMBL:BC026956 xref: HGNC:HGNC:30022 xref: UniGene:Hs.591261 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057308 ! PRGC2_HUMAN relationship: codes_for CCO:B0057889 ! Q8TAL0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019509 name: PGR_human def: "Progesterone receptor gene" [UniProtKB:P06401] synonym: "NR3C3" EXACT [UniProtKB:P06401] xref: EMBL:AF016381 xref: EMBL:AY525610 xref: EMBL:M15716 xref: EMBL:X51730 xref: HGNC:HGNC:8910 xref: UniGene:Hs.368072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054904 ! PRGR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019510 name: PRKRA_human def: "Interferon-inducible double stranded RNA-dependent protein kinase activator A gene" [UniProtKB:O75569] synonym: "HSD-14" EXACT [UniProtKB:O75569] synonym: "HSD14" EXACT [UniProtKB:O75569] synonym: "PACT" EXACT [UniProtKB:O75569] synonym: "RAX" EXACT [UniProtKB:O75569] xref: EMBL:AC009948 xref: EMBL:AF072860 xref: EMBL:AF083033 xref: EMBL:AK223107 xref: EMBL:AL136615 xref: EMBL:AL833867 xref: EMBL:AY251164 xref: EMBL:BC009470 xref: EMBL:BT007243 xref: EMBL:CR533525 xref: HGNC:HGNC:9438 xref: UniGene:Hs.632540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054651 ! PRKRA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019511 name: PRLHR_human def: "Prolactin-releasing peptide receptor gene" [UniProtKB:P49683] synonym: "GPR10" EXACT [UniProtKB:P49683] synonym: "GR3" EXACT [UniProtKB:P49683] xref: EMBL:AB015745 xref: EMBL:AB048946 xref: EMBL:AL356865 xref: EMBL:BC095539 xref: EMBL:BC101490 xref: EMBL:BC101492 xref: EMBL:U32672 xref: HGNC:HGNC:4464 xref: UniGene:Hs.248119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055429 ! PRLHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019512 name: PRLR_human def: "Prolactin receptor precursor gene" [UniProtKB:P16471] xref: EMBL:AF091863 xref: EMBL:AF091864 xref: EMBL:AF091865 xref: EMBL:AF091866 xref: EMBL:AF091867 xref: EMBL:AF091868 xref: EMBL:AF091869 xref: EMBL:AF091870 xref: EMBL:AF166329 xref: EMBL:AF349939 xref: EMBL:AF416618 xref: EMBL:AF416619 xref: EMBL:AF492470 xref: EMBL:AF493069 xref: EMBL:BC059392 xref: EMBL:M31661 xref: EMBL:S78505 xref: HGNC:HGNC:9446 xref: UniGene:Hs.368587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055053 ! PRLR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019513 name: PRL_human def: "Prolactin precursor gene" [UniProtKB:P01236] xref: EMBL:BC015850 xref: EMBL:D00411 xref: EMBL:M29386 xref: EMBL:U75583 xref: EMBL:V00566 xref: EMBL:X00540 xref: EMBL:X00541 xref: EMBL:X00543 xref: EMBL:X00544 xref: EMBL:X54393 xref: HGNC:HGNC:9445 xref: UniGene:Hs.1905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054842 ! PRL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019514 name: PROC_human def: "Vitamin K-dependent protein C precursor gene" [UniProtKB:P04070] xref: EMBL:AF378903 xref: EMBL:BC034377 xref: EMBL:K02059 xref: EMBL:M11228 xref: EMBL:M12683 xref: EMBL:M12684 xref: EMBL:M12685 xref: EMBL:M12686 xref: EMBL:M12687 xref: EMBL:M12712 xref: EMBL:S58668 xref: EMBL:S76088 xref: EMBL:S76090 xref: EMBL:X02750 xref: HGNC:HGNC:9451 xref: UniGene:Hs.224698 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054884 ! PROC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019515 name: PRODH_human def: "Proline oxidase, mitochondrial precursor gene" [UniProtKB:O43272] synonym: "PIG6" EXACT [UniProtKB:O43272] synonym: "POX2" EXACT [UniProtKB:O43272] xref: EMBL:AB209472 xref: EMBL:AC007326 xref: EMBL:AF010310 xref: EMBL:AF120278 xref: EMBL:BC068260 xref: EMBL:BC094736 xref: EMBL:BC118597 xref: EMBL:BC121809 xref: EMBL:U79754 xref: EMBL:U82381 xref: HGNC:HGNC:9453 xref: UniGene:Hs.517352 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054465 ! PROD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019516 name: PROK2_human def: "Prokineticin-2 precursor gene" [UniProtKB:Q9HC23] synonym: "BV8" EXACT [UniProtKB:Q9HC23] xref: EMBL:AF182069 xref: EMBL:AF333025 xref: EMBL:AY349131 xref: EMBL:BC098162 xref: HGNC:HGNC:18455 xref: UniGene:Hs.528665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017123 ! PROK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019517 name: PROP1_human def: "Homeobox protein prophet of Pit-1 gene" [UniProtKB:O75360] xref: EMBL:AF041139 xref: EMBL:AF041140 xref: EMBL:AF041141 xref: EMBL:AF076214 xref: EMBL:AF076215 xref: EMBL:BC069076 xref: HGNC:HGNC:9455 xref: UniGene:Hs.158301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054622 ! PROP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019518 name: PROX1_human def: "Prospero homeobox protein 1 gene" [UniProtKB:Q92786] xref: EMBL:AC011700 xref: EMBL:AK290176 xref: EMBL:AL606537 xref: EMBL:BC024201 xref: EMBL:CH471100 xref: EMBL:U44060 xref: HGNC:HGNC:9459 xref: UniGene:Hs.585369 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058095 ! PROX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019519 name: PRPF19_human def: "Pre-mRNA-processing factor 19 gene" [UniProtKB:Q9UMS4] synonym: "NMP200" EXACT [UniProtKB:Q9UMS4] synonym: "PRP19" EXACT [UniProtKB:Q9UMS4] synonym: "SNEV" EXACT [UniProtKB:Q9UMS4] xref: EMBL:AJ131186 xref: EMBL:BC008719 xref: EMBL:BC018665 xref: EMBL:BC018698 xref: HGNC:HGNC:17896 xref: UniGene:Hs.502705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016149 ! PRP19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019520 name: PRPF6_human def: "Pre-mRNA-processing factor 6 gene" [UniProtKB:O94906] synonym: "C20orf14" EXACT [UniProtKB:O94906] xref: EMBL:AB019219 xref: EMBL:AF026031 xref: EMBL:AF221842 xref: EMBL:AL118506 xref: EMBL:AL137320 xref: EMBL:AL355803 xref: EMBL:AL356790 xref: EMBL:BC001666 xref: HGNC:HGNC:15860 xref: UniGene:Hs.31334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054708 ! PRP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019521 name: PRRX1_human def: "Paired mesoderm homeobox protein 1 gene" [UniProtKB:P54821] synonym: "PMX1" EXACT [UniProtKB:P54821] xref: EMBL:BC074993 xref: EMBL:M95929 xref: EMBL:Z97200 xref: HGNC:HGNC:9142 xref: UniGene:Hs.702224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055517 ! PRRX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019522 name: PRRX2_human def: "Paired mesoderm homeobox protein 2 gene" [UniProtKB:Q99811] synonym: "PMX2" EXACT [UniProtKB:Q99811] synonym: "PRX2" EXACT [UniProtKB:Q99811] xref: EMBL:AF061970 xref: EMBL:BC014645 xref: EMBL:U81600 xref: HGNC:HGNC:21338 xref: UniGene:Hs.660115 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058456 ! PRRX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019523 name: PRTN3_human def: "Myeloblastin precursor gene" [UniProtKB:P24158] synonym: "MBN" EXACT [UniProtKB:P24158] xref: EMBL:AC004799 xref: EMBL:AF015446 xref: EMBL:AF015447 xref: EMBL:AF015448 xref: EMBL:AF015449 xref: EMBL:BC096183 xref: EMBL:BC096185 xref: EMBL:M29142 xref: EMBL:M75154 xref: EMBL:M96628 xref: EMBL:M96837 xref: EMBL:M96838 xref: EMBL:M96839 xref: EMBL:M97911 xref: EMBL:X55668 xref: EMBL:X56132 xref: EMBL:X56606 xref: HGNC:HGNC:9495 xref: UniGene:Hs.928 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055168 ! PRTN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019524 name: PSD_human def: "PH and SEC7 domain-containing protein 1 gene" [UniProtKB:A5PKW4] synonym: "EFA6" EXACT [UniProtKB:A5PKW4] synonym: "KIAA2011" EXACT [UniProtKB:A5PKW4] synonym: "PSD1" EXACT [UniProtKB:A5PKW4] synonym: "TYL" EXACT [UniProtKB:A5PKW4] xref: EMBL:AB095931 xref: EMBL:AL121928 xref: EMBL:BC142643 xref: EMBL:BC142689 xref: EMBL:CH471066 xref: EMBL:X99688 xref: HGNC:HGNC:9507 xref: UniGene:Hs.154658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053775 ! PSD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019525 name: PSD2_human def: "PH and SEC7 domain-containing protein 2 gene" [UniProtKB:Q9BQI7] xref: EMBL:AL136559 xref: EMBL:AL834268 xref: EMBL:BC038233 xref: EMBL:CH471062 xref: HGNC:HGNC:19092 xref: UniGene:Hs.21963 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058482 ! PSD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019526 name: PSD3_human def: "PH and SEC7 domain-containing protein 3 gene" [UniProtKB:Q9NYI0] synonym: "EFA6R" EXACT [UniProtKB:Q9NYI0] synonym: "HCA67" EXACT [UniProtKB:Q9NYI0] synonym: "KIAA0942" EXACT [UniProtKB:Q9NYI0] xref: EMBL:AB023159 xref: EMBL:AC009884 xref: EMBL:AC087821 xref: EMBL:AC090420 xref: EMBL:AC100800 xref: EMBL:AC120051 xref: EMBL:AF243495 xref: EMBL:AF519767 xref: EMBL:BC075044 xref: EMBL:BC075045 xref: HGNC:HGNC:19093 xref: UniGene:Hs.434255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058963 ! PSD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019527 name: PSD4_human def: "PH and SEC7 domain-containing protein 4 gene" [UniProtKB:Q8NDX1] synonym: "EFA6B" EXACT [UniProtKB:Q8NDX1] synonym: "TIC" EXACT [UniProtKB:Q8NDX1] xref: EMBL:AC016683 xref: EMBL:AJ459781 xref: EMBL:BC035307 xref: EMBL:BC073151 xref: EMBL:DQ452296 xref: EMBL:U63127 xref: HGNC:HGNC:19096 xref: UniGene:Hs.699333 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057584 ! PSD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019528 name: GINS1_human def: "DNA replication complex GINS protein PSF1 gene" [UniProtKB:Q14691] synonym: "KIAA0186" EXACT [UniProtKB:Q14691] synonym: "PSF1" EXACT [UniProtKB:Q14691] xref: EMBL:AL031672 xref: EMBL:AL353812 xref: EMBL:BC012542 xref: EMBL:D80008 xref: HGNC:HGNC:28980 xref: UniGene:Hs.658464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056011 ! PSF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019529 name: GINS3_human def: "DNA replication complex GINS protein PSF3 gene" [UniProtKB:Q9BRX5] synonym: "PSF3" EXACT [UniProtKB:Q9BRX5] xref: EMBL:AK023974 xref: EMBL:BC005879 xref: EMBL:BC014437 xref: EMBL:CH471092 xref: EMBL:CR457283 xref: HGNC:HGNC:25851 xref: UniGene:Hs.47125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058500 ! PSF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019530 name: PSIP1_human def: "PC4 and SFRS1-interacting protein gene" [UniProtKB:O75475] synonym: "DFS70" EXACT [UniProtKB:O75475] synonym: "LEDGF" EXACT [UniProtKB:O75475] synonym: "PSIP2" EXACT [UniProtKB:O75475] xref: EMBL:AF063020 xref: EMBL:AF098482 xref: EMBL:AF098483 xref: EMBL:AF199339 xref: EMBL:AF432220 xref: EMBL:AL359998 xref: EMBL:AL441925 xref: EMBL:AL513423 xref: EMBL:BC044568 xref: EMBL:BC064135 xref: EMBL:U94319 xref: HGNC:HGNC:9527 xref: UniGene:Hs.658434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054642 ! PSIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019531 name: PSEN2_human def: "Presenilin-2 gene" [UniProtKB:P49810] synonym: "AD4" EXACT [UniProtKB:P49810] synonym: "PS2" EXACT [UniProtKB:P49810] synonym: "PSNL2" EXACT [UniProtKB:P49810] synonym: "STM2" EXACT [UniProtKB:P49810] xref: EMBL:AF416718 xref: EMBL:AK292299 xref: EMBL:AL391628 xref: EMBL:BC006365 xref: EMBL:BT006984 xref: EMBL:CH471098 xref: EMBL:L43964 xref: EMBL:L44577 xref: EMBL:U34349 xref: EMBL:U50871 xref: HGNC:HGNC:9509 xref: UniGene:Hs.25363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053978 ! A8K8D4_HUMAN relationship: codes_for CCO:B0054267 ! B1AP22_HUMAN relationship: codes_for CCO:B0055439 ! PSN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019532 name: PSPC1_human def: "Paraspeckle component 1 gene" [UniProtKB:Q8WXF1] synonym: "PSP1" EXACT [UniProtKB:Q8WXF1] xref: EMBL:AF448795 xref: EMBL:AF449627 xref: EMBL:AK001817 xref: EMBL:AL354808 xref: EMBL:AL834505 xref: EMBL:BC014184 xref: EMBL:CH471075 xref: EMBL:CR457272 xref: HGNC:HGNC:20320 xref: UniGene:Hs.213198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058017 ! PSPC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019533 name: PSPHL_human def: "Putative phosphoserine phosphatase-like protein gene" [UniProtKB:O15172] synonym: "CO9" EXACT [UniProtKB:O15172] xref: EMBL:AJ001612 xref: EMBL:BT006661 xref: HGNC:HGNC:9578 xref: UniGene:Hs.536913 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054412 ! PSPHL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019534 name: PSTK_human def: "L-seryl-tRNA(Sec) kinase gene" [UniProtKB:Q8IV42] synonym: "C10orf89" EXACT [UniProtKB:Q8IV42] xref: EMBL:AK127173 xref: EMBL:BC035344 xref: HGNC:HGNC:28578 xref: UniGene:Hs.281004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057334 ! PSTK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019535 name: GPR65_human def: "Psychosine receptor gene" [UniProtKB:Q8IYL9] synonym: "TDAG8" EXACT [UniProtKB:Q8IYL9] xref: EMBL:AL157955 xref: EMBL:BC035633 xref: EMBL:BC071715 xref: EMBL:U95218 xref: HGNC:HGNC:4517 xref: UniGene:Hs.513440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024306 ! PSYR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019536 name: PTPLAD1_human def: "Protein tyrosine phosphatase-like protein PTPLAD1 gene" [UniProtKB:Q9P035] synonym: "BIND1" EXACT [UniProtKB:Q9P035] xref: EMBL:AF161470 xref: EMBL:AJ271091 xref: EMBL:AK027421 xref: EMBL:AK074857 xref: EMBL:AK074898 xref: EMBL:BC019873 xref: EMBL:BC035508 xref: EMBL:BC047685 xref: EMBL:BC058912 xref: EMBL:DQ251107 xref: HGNC:HGNC:24175 xref: UniGene:Hs.512973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059026 ! PTAD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019537 name: PTAFR_human def: "Platelet-activating factor receptor gene" [UniProtKB:P25105] synonym: "PAFR" EXACT [UniProtKB:P25105] xref: EMBL:AY275466 xref: EMBL:BC013816 xref: EMBL:BC063000 xref: EMBL:BT009801 xref: EMBL:D10202 xref: EMBL:L07334 xref: EMBL:M76674 xref: EMBL:M80436 xref: EMBL:M88177 xref: EMBL:S52624 xref: EMBL:S56396 xref: HGNC:HGNC:9582 xref: UniGene:Hs.433540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055181 ! PTAFR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019538 name: PTF1A_human def: "Pancreas transcription factor 1 subunit alpha gene" [UniProtKB:Q7RTS3] synonym: "PTF1P48" EXACT [UniProtKB:Q7RTS3] xref: EMBL:AF181999 xref: EMBL:AL139281 xref: EMBL:BK000272 xref: HGNC:HGNC:23734 xref: UniGene:Hs.351503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057127 ! PTF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019539 name: PTGDS2_human def: "Glutathione-requiring prostaglandin D synthase gene" [UniProtKB:O60760] synonym: "PGDS" EXACT [UniProtKB:O60760] xref: EMBL:AB008830 xref: EMBL:BC020734 xref: EMBL:D82073 xref: UniGene:Hs.128433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054578 ! PTGD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019540 name: PTGES_human def: "Prostaglandin E synthase gene" [UniProtKB:O14684] synonym: "MGST1L1" EXACT [UniProtKB:O14684] synonym: "PGES" EXACT [UniProtKB:O14684] synonym: "PIG12" EXACT [UniProtKB:O14684] xref: EMBL:AF010316 xref: EMBL:AF027740 xref: EMBL:AJ271802 xref: EMBL:AJ271803 xref: EMBL:AJ271804 xref: EMBL:BC008280 xref: HGNC:HGNC:9599 xref: UniGene:Hs.146688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054367 ! PTGES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019541 name: PTH2R_human def: "Parathyroid hormone 2 receptor precursor gene" [UniProtKB:P49190] synonym: "PTHR2" EXACT [UniProtKB:P49190] xref: EMBL:AY497546 xref: EMBL:BC036811 xref: EMBL:U25128 xref: EMBL:U47124 xref: EMBL:U47125 xref: EMBL:U47126 xref: EMBL:U47127 xref: EMBL:U47128 xref: EMBL:U47129 xref: HGNC:HGNC:9609 xref: UniGene:Hs.570296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055419 ! PTH2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019542 name: PTHR1_human def: "Parathyroid hormone/parathyroid hormone-related peptide receptor precursor gene" [UniProtKB:Q03431] synonym: "PTHR" EXACT [UniProtKB:Q03431] xref: EMBL:AY449732 xref: EMBL:BC112221 xref: EMBL:BC112247 xref: EMBL:L04308 xref: EMBL:U17418 xref: EMBL:U22401 xref: EMBL:U22402 xref: EMBL:U22403 xref: EMBL:U22404 xref: EMBL:U22405 xref: EMBL:U22406 xref: EMBL:U22407 xref: EMBL:U22408 xref: EMBL:U22409 xref: EMBL:X68596 xref: HGNC:HGNC:9608 xref: UniGene:Hs.1019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055724 ! PTHR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019543 name: PTHLH_human def: "Parathyroid hormone-related protein precursor gene" [UniProtKB:P12272] synonym: "PTHRP" EXACT [UniProtKB:P12272] xref: EMBL:BC005961 xref: EMBL:J03580 xref: EMBL:J03802 xref: EMBL:M17183 xref: EMBL:M24348 xref: EMBL:M24349 xref: EMBL:M24350 xref: EMBL:M24351 xref: EMBL:M34071 xref: EMBL:X14304 xref: HGNC:HGNC:9607 xref: UniGene:Hs.591159 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054999 ! PTHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019544 name: PTH_human def: "Parathyroid hormone precursor gene" [UniProtKB:P01270] xref: EMBL:BC096142 xref: EMBL:BC096143 xref: EMBL:BC096144 xref: EMBL:BC096145 xref: EMBL:J00301 xref: EMBL:V00597 xref: HGNC:HGNC:9606 xref: UniGene:Hs.37045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054847 ! PTHY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019545 name: PTK7_human def: "Tyrosine-protein kinase-like 7 precursor gene" [UniProtKB:Q13308] synonym: "CCK4" EXACT [UniProtKB:Q13308] xref: EMBL:AF447157 xref: EMBL:AF447158 xref: EMBL:AF447162 xref: EMBL:AF447164 xref: EMBL:AF447167 xref: EMBL:AF447170 xref: EMBL:AF447171 xref: EMBL:AF447173 xref: EMBL:AF447174 xref: EMBL:AF447175 xref: EMBL:AF447176 xref: EMBL:U33635 xref: EMBL:U40271 xref: HGNC:HGNC:9618 xref: UniGene:Hs.90572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055896 ! PTK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019546 name: PTPN11_human def: "Tyrosine-protein phosphatase non-receptor type 11 gene" [UniProtKB:Q06124] synonym: "PTP2C" EXACT [UniProtKB:Q06124] synonym: "SHPTP2" EXACT [UniProtKB:Q06124] xref: EMBL:BC008692 xref: EMBL:BT007106 xref: EMBL:D13540 xref: EMBL:L03535 xref: EMBL:L07527 xref: EMBL:L08807 xref: EMBL:X70766 xref: HGNC:HGNC:9644 xref: UniGene:Hs.506852 xref: UniGene:Hs.646231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055765 ! PTN11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019547 name: PTPN1_human def: "Tyrosine-protein phosphatase non-receptor type 1 gene" [UniProtKB:P18031] synonym: "PTP1B" EXACT [UniProtKB:P18031] xref: EMBL:AL034429 xref: EMBL:AL133230 xref: EMBL:BC015660 xref: EMBL:BC018164 xref: EMBL:BT006752 xref: EMBL:M31724 xref: EMBL:M33684 xref: EMBL:M33685 xref: EMBL:M33686 xref: EMBL:M33687 xref: EMBL:M33688 xref: EMBL:M33689 xref: HGNC:HGNC:9642 xref: UniGene:Hs.417549 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055096 ! PTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019548 name: PTPN22_human def: "Tyrosine-protein phosphatase non-receptor type 22 gene" [UniProtKB:Q9Y2R2] synonym: "PTPN8" EXACT [UniProtKB:Q9Y2R2] xref: EMBL:AF001846 xref: EMBL:AF001847 xref: EMBL:AF077031 xref: HGNC:HGNC:9652 xref: UniGene:Hs.535276 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059314 ! PTN22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019549 name: PTPRD_human def: "Receptor-type tyrosine-protein phosphatase delta precursor gene" [UniProtKB:P23468] xref: EMBL:AL137125 xref: EMBL:AL356584 xref: EMBL:AL445926 xref: EMBL:AL583805 xref: EMBL:AL590397 xref: EMBL:L38929 xref: EMBL:X54133 xref: HGNC:HGNC:9668 xref: UniGene:Hs.446083 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055157 ! PTPRD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019550 name: PTPRF_human def: "Receptor-type tyrosine-protein phosphatase F precursor gene" [UniProtKB:P10586] synonym: "LAR" EXACT [UniProtKB:P10586] xref: EMBL:Y00815 xref: HGNC:HGNC:9670 xref: UniGene:Hs.272062 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054975 ! PTPRF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019551 name: PTPRG_human def: "Receptor-type tyrosine-protein phosphatase gamma precursor gene" [UniProtKB:P23470] synonym: "PTPG" EXACT [UniProtKB:P23470] xref: EMBL:AB209871 xref: EMBL:CR749269 xref: EMBL:L09247 xref: EMBL:U46089 xref: EMBL:U46090 xref: EMBL:U46091 xref: EMBL:U46092 xref: EMBL:U46093 xref: EMBL:U46094 xref: EMBL:U46095 xref: EMBL:U46096 xref: EMBL:U46097 xref: EMBL:U46098 xref: EMBL:U46099 xref: EMBL:U46100 xref: EMBL:U46101 xref: EMBL:U46102 xref: EMBL:U46103 xref: EMBL:U46104 xref: EMBL:U46105 xref: EMBL:U46106 xref: EMBL:U46107 xref: EMBL:U46108 xref: EMBL:U46109 xref: EMBL:U46110 xref: EMBL:U46111 xref: EMBL:U46112 xref: EMBL:U46113 xref: EMBL:U46114 xref: EMBL:U46115 xref: EMBL:U46116 xref: EMBL:X54132 xref: HGNC:HGNC:9671 xref: UniGene:Hs.654488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055158 ! PTPRG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019552 name: PTPRJ_human def: "Receptor-type tyrosine-protein phosphatase eta precursor gene" [UniProtKB:Q12913] synonym: "DEP1" EXACT [UniProtKB:Q12913] xref: EMBL:AC026975 xref: EMBL:AC103828 xref: EMBL:AF387823 xref: EMBL:AF387824 xref: EMBL:AF387825 xref: EMBL:AF387826 xref: EMBL:AF387827 xref: EMBL:AF387828 xref: EMBL:AF387829 xref: EMBL:AF387830 xref: EMBL:AF387831 xref: EMBL:AF387832 xref: EMBL:AF387833 xref: EMBL:AF387834 xref: EMBL:AF387835 xref: EMBL:AF387836 xref: EMBL:AF387837 xref: EMBL:AF387838 xref: EMBL:AF387839 xref: EMBL:AF387840 xref: EMBL:AF387841 xref: EMBL:AF387842 xref: EMBL:AF387843 xref: EMBL:AF387844 xref: EMBL:D37781 xref: EMBL:U10886 xref: HGNC:HGNC:9673 xref: UniGene:Hs.318547 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055856 ! PTPRJ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019553 name: PTPRT_human def: "Receptor-type tyrosine-protein phosphatase T precursor gene" [UniProtKB:O14522] synonym: "KIAA0283" EXACT [UniProtKB:O14522] xref: EMBL:AB006621 xref: EMBL:AF043644 xref: EMBL:AL021395 xref: EMBL:AL022239 xref: EMBL:AL024473 xref: EMBL:AL031656 xref: EMBL:AL035459 xref: EMBL:AL049812 xref: EMBL:AL121763 xref: EMBL:AL136461 xref: EMBL:Z93942 xref: HGNC:HGNC:9682 xref: UniGene:Hs.526879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023006 ! PTPRT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019554 name: PTPRU_human def: "Receptor-type tyrosine-protein phosphatase U precursor gene" [UniProtKB:Q92729] synonym: "PCP2" EXACT [UniProtKB:Q92729] xref: EMBL:X97198 xref: HGNC:HGNC:9683 xref: UniGene:Hs.19718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023019 ! PTPRU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019555 name: PTRF_human def: "Polymerase I and transcript release factor gene" [UniProtKB:Q6NZI2] synonym: "FKSG13" EXACT [UniProtKB:Q6NZI2] xref: EMBL:AF000421 xref: EMBL:AF312393 xref: EMBL:BC004295 xref: EMBL:BC008849 xref: EMBL:BC066123 xref: EMBL:BC073759 xref: HGNC:HGNC:9688 xref: UniGene:Hs.437191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056873 ! PTRF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019556 name: PTX3_human def: "Pentraxin-related protein PTX3 precursor gene" [UniProtKB:P26022] synonym: "TNFAIP5" EXACT [UniProtKB:P26022] synonym: "TSG14" EXACT [UniProtKB:P26022] xref: EMBL:BC039733 xref: EMBL:CH471052 xref: EMBL:DQ207368 xref: EMBL:M31166 xref: EMBL:X63053 xref: EMBL:X63613 xref: HGNC:HGNC:9692 xref: UniGene:Hs.591286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055190 ! PTX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019557 name: PUF60_human def: "Poly(U)-binding-splicing factor PUF60 gene" [UniProtKB:Q9UHX1] synonym: "FIR" EXACT [UniProtKB:Q9UHX1] synonym: "ROBPI" EXACT [UniProtKB:Q9UHX1] synonym: "SIAHBP1" EXACT [UniProtKB:Q9UHX1] xref: EMBL:AF114818 xref: EMBL:AF190744 xref: EMBL:AF217197 xref: EMBL:BC008875 xref: EMBL:BC009734 xref: EMBL:BC011265 xref: EMBL:BC011979 xref: EMBL:CH471162 xref: EMBL:CR457143 xref: EMBL:U51586 xref: HGNC:HGNC:17042 xref: UniGene:Hs.521924 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059151 ! PUF60_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019558 name: PUM1_human def: "Pumilio homolog 1 gene" [UniProtKB:Q14671] synonym: "KIAA0099" EXACT [UniProtKB:Q14671] synonym: "PUMH1" EXACT [UniProtKB:Q14671] xref: EMBL:AF315592 xref: EMBL:AL356320 xref: EMBL:AL445235 xref: EMBL:BC013398 xref: EMBL:D43951 xref: HGNC:HGNC:14957 xref: UniGene:Hs.281707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024392 ! PUM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019559 name: PUM2_human def: "Pumilio homolog 2 gene" [UniProtKB:Q8TB72] synonym: "KIAA0235" EXACT [UniProtKB:Q8TB72] synonym: "PUMH2" EXACT [UniProtKB:Q8TB72] xref: EMBL:AC007041 xref: EMBL:AF272350 xref: EMBL:AF315591 xref: EMBL:BC024218 xref: EMBL:BC112046 xref: EMBL:BC112048 xref: EMBL:D87078 xref: HGNC:HGNC:14958 xref: UniGene:Hs.467824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024383 ! PUM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019560 name: PURA_human def: "Transcriptional activator protein Pur-alpha gene" [UniProtKB:Q00577] synonym: "PUR1" EXACT [UniProtKB:Q00577] xref: EMBL:M96684 xref: EMBL:U02098 xref: HGNC:HGNC:9701 xref: UniGene:Hs.443121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055679 ! PURA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019561 name: PWP2_human def: "Periodic tryptophan protein 2 homolog gene" [UniProtKB:Q15269] synonym: "PWP2H" EXACT [UniProtKB:Q15269] xref: EMBL:AB001517 xref: EMBL:AB001523 xref: EMBL:AP001753 xref: EMBL:BC013309 xref: EMBL:BC014988 xref: EMBL:U53346 xref: EMBL:U56085 xref: EMBL:U56086 xref: EMBL:U56087 xref: EMBL:U56088 xref: EMBL:U56089 xref: EMBL:X95263 xref: EMBL:X96424 xref: EMBL:X96425 xref: HGNC:HGNC:9711 xref: UniGene:Hs.449076 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056050 ! PWP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019562 name: PEX11A_human def: "Peroxisomal membrane protein 11A gene" [UniProtKB:O75192] synonym: "PEX11" EXACT [UniProtKB:O75192] xref: EMBL:AB015594 xref: EMBL:AF093668 xref: EMBL:BC009697 xref: EMBL:CR542046 xref: EMBL:CR542075 xref: HGNC:HGNC:8852 xref: UniGene:Hs.31034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054613 ! PX11A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019563 name: PEX11B_human def: "Peroxisomal membrane protein 11B gene" [UniProtKB:O96011] xref: EMBL:AB018080 xref: EMBL:AF093670 xref: EMBL:BC011963 xref: EMBL:CR542047 xref: HGNC:HGNC:8853 xref: UniGene:Hs.699232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054820 ! PX11B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019564 name: PYGO1_human def: "Pygopus homolog 1 gene" [UniProtKB:Q9Y3Y4] xref: EMBL:AF457207 xref: EMBL:AL049925 xref: HGNC:HGNC:30256 xref: UniGene:Hs.256587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059345 ! PYGO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019565 name: PYY_human def: "Peptide YY precursor gene" [UniProtKB:P10082] xref: EMBL:AC007993 xref: EMBL:BC041057 xref: EMBL:CR542129 xref: EMBL:D13897 xref: EMBL:D13899 xref: EMBL:D13902 xref: EMBL:L25648 xref: HGNC:HGNC:9748 xref: UniGene:Hs.169249 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054969 ! PYY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019566 name: QKI_human def: "Protein quaking gene" [UniProtKB:Q96PU8] synonym: "HKQ" EXACT [UniProtKB:Q96PU8] xref: EMBL:AB067798 xref: EMBL:AB067799 xref: EMBL:AB067800 xref: EMBL:AB067801 xref: EMBL:AB067808 xref: EMBL:AF142417 xref: EMBL:AF142418 xref: EMBL:AF142419 xref: EMBL:AF142420 xref: EMBL:AF142421 xref: EMBL:AF142422 xref: EMBL:AK027309 xref: EMBL:AL031781 xref: EMBL:AL356119 xref: EMBL:AY780788 xref: EMBL:BC012222 xref: EMBL:BC019917 xref: EMBL:DQ323998 xref: HGNC:HGNC:21100 xref: UniGene:Hs.510324 xref: UniGene:Hs.593520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058345 ! QKI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019567 name: TP53I3_human def: "Putative quinone oxidoreductase gene" [UniProtKB:Q53FA7] synonym: "PIG3" EXACT [UniProtKB:Q53FA7] xref: EMBL:AC008073 xref: EMBL:AF010309 xref: EMBL:AF010317 xref: EMBL:AK223382 xref: EMBL:AY371700 xref: EMBL:BC000474 xref: EMBL:BT007149 xref: EMBL:DQ232851 xref: HGNC:HGNC:19373 xref: UniGene:Hs.50649 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056356 ! QORX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019568 name: GPR103_human def: "Orexigenic neuropeptide QRFP receptor gene" [UniProtKB:Q96P65] xref: EMBL:AB109629 xref: EMBL:AF411117 xref: HGNC:HGNC:15565 xref: UniGene:Hs.368977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058320 ! QRFPR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019569 name: RGS7BP_human def: "Regulator of G-protein signaling 7-binding protein gene" [UniProtKB:Q6MZT1] synonym: "R7BP" EXACT [UniProtKB:Q6MZT1] xref: EMBL:AC008854 xref: EMBL:AC035143 xref: EMBL:AC091862 xref: EMBL:BX640900 xref: HGNC:HGNC:23271 xref: UniGene:Hs.657133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056842 ! R7BP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019570 name: RGS9BP_human def: "Regulator of G-protein signaling 9-binding protein gene" [UniProtKB:Q6ZS82] synonym: "R9AP" EXACT [UniProtKB:Q6ZS82] xref: EMBL:AK124499 xref: EMBL:AK127646 xref: HGNC:HGNC:30304 xref: UniGene:Hs.528491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057050 ! R9BP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019571 name: RAB12_human def: "Putative Ras-related protein Rab-12 gene" [UniProtKB:Q6IQ22] xref: EMBL:AP001793 xref: EMBL:BC050338 xref: EMBL:BC071600 xref: EMBL:BC098407 xref: EMBL:CH471113 xref: HGNC:HGNC:31332 xref: UniGene:Hs.270074 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056826 ! RAB12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019572 name: RAB14_human def: "Ras-related protein Rab-14 gene" [UniProtKB:P61106] xref: EMBL:AF112206 xref: EMBL:AF152463 xref: EMBL:AF203689 xref: EMBL:AF498949 xref: EMBL:AK023524 xref: EMBL:AL137068 xref: EMBL:AL162081 xref: EMBL:AY553875 xref: EMBL:BC006081 xref: EMBL:CR457394 xref: HGNC:HGNC:16524 xref: UniGene:Hs.371563 xref: UniGene:Hs.705444 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055604 ! RAB14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019573 name: RAB15_human def: "Ras-related protein Rab-15 gene" [UniProtKB:P59190] xref: EMBL:AL139022 xref: EMBL:BC040679 xref: EMBL:BX248046 xref: HGNC:HGNC:20150 xref: UniGene:Hs.512492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055575 ! RAB15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019574 name: RAB17_human def: "Ras-related protein Rab-17 gene" [UniProtKB:Q9H0T7] xref: EMBL:AK022600 xref: EMBL:AL136645 xref: EMBL:BC000929 xref: EMBL:BC050426 xref: HGNC:HGNC:16523 xref: UniGene:Hs.702458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058657 ! RAB17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019575 name: RAB18_human def: "Ras-related protein Rab-18 gene" [UniProtKB:Q9NP72] xref: EMBL:AF087860 xref: EMBL:AF136974 xref: EMBL:AF137372 xref: EMBL:AF498950 xref: EMBL:AJ277145 xref: EMBL:AJ277146 xref: EMBL:AJ277147 xref: EMBL:AJ277148 xref: EMBL:AJ277149 xref: EMBL:AK223153 xref: EMBL:AL136734 xref: EMBL:AL138920 xref: EMBL:AY574034 xref: EMBL:BC015014 xref: EMBL:BC029350 xref: EMBL:BT009840 xref: EMBL:CR533455 xref: HGNC:HGNC:14244 xref: UniGene:Hs.406799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056373 ! Q56UN9_HUMAN relationship: codes_for CCO:B0056678 ! Q5W0I9_HUMAN relationship: codes_for CCO:B0056679 ! Q5W0J0_HUMAN relationship: codes_for CCO:B0058836 ! RAB18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019576 name: RAB19_human def: "Ras-related protein Rab-19 gene" [UniProtKB:A4D1S5] synonym: "RAB19B" EXACT [UniProtKB:A4D1S5] xref: EMBL:AF091033 xref: EMBL:CH236950 xref: HGNC:HGNC:19982 xref: UniGene:Hs.583545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053752 ! RAB19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019577 name: RAB1B_human def: "Ras-related protein Rab-1B gene" [UniProtKB:Q9H0U4] xref: EMBL:AF092437 xref: EMBL:AL136635 xref: EMBL:BC071169 xref: HGNC:HGNC:18370 xref: UniGene:Hs.300816 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026021 ! RAB1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019578 name: RAB20_human def: "Ras-related protein Rab-20 gene" [UniProtKB:Q9NX57] xref: EMBL:AJ272065 xref: EMBL:AK000436 xref: EMBL:AK000446 xref: EMBL:BC026025 xref: HGNC:HGNC:18260 xref: UniGene:Hs.508720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058949 ! RAB20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019579 name: RAB21_human def: "Ras-related protein Rab-21 gene" [UniProtKB:Q9UL25] synonym: "KIAA0118" EXACT [UniProtKB:Q9UL25] xref: EMBL:AF091035 xref: EMBL:BC021901 xref: EMBL:BC092475 xref: EMBL:D42087 xref: HGNC:HGNC:18263 xref: UniGene:Hs.524590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059214 ! RAB21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019580 name: RAB23_human def: "Ras-related protein Rab-23 gene" [UniProtKB:Q9ULC3] synonym: "HSPC137" EXACT [UniProtKB:Q9ULC3] xref: EMBL:AB025427 xref: EMBL:AB034244 xref: EMBL:AF161486 xref: EMBL:AF498951 xref: EMBL:AL031321 xref: EMBL:AY585189 xref: EMBL:BC015021 xref: HGNC:HGNC:14263 xref: UniGene:Hs.555016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059221 ! RAB23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019581 name: RAB24_human def: "Ras-related protein Rab-24 gene" [UniProtKB:Q969Q5] xref: EMBL:AC146507 xref: EMBL:AF087904 xref: EMBL:AF258583 xref: EMBL:AK021761 xref: EMBL:AL833898 xref: EMBL:BC010006 xref: EMBL:BC015534 xref: EMBL:BC021263 xref: EMBL:BT007268 xref: EMBL:CH471195 xref: HGNC:HGNC:9765 xref: UniGene:Hs.16258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054014 ! A8MSV4_HUMAN relationship: codes_for CCO:B0058040 ! Q8WY67_HUMAN relationship: codes_for CCO:B0058139 ! RAB24_HUMAN relationship: codes_for CCO:B0058760 ! Q9HAG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019582 name: RAB25_human def: "Ras-related protein Rab-25 gene" [UniProtKB:P57735] synonym: "CATX8" EXACT [UniProtKB:P57735] xref: EMBL:AF083124 xref: EMBL:AF274025 xref: EMBL:AL355388 xref: EMBL:BC004416 xref: EMBL:BC009831 xref: EMBL:BC033322 xref: EMBL:CH471121 xref: HGNC:HGNC:18238 xref: UniGene:Hs.632469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055560 ! RAB25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019583 name: RAB26_human def: "Ras-related protein Rab-26 gene" [UniProtKB:Q9ULW5] xref: EMBL:AB027137 xref: EMBL:AC009065 xref: EMBL:AF498952 xref: EMBL:BC066913 xref: HGNC:HGNC:14259 xref: UniGene:Hs.3797 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059236 ! RAB26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019584 name: RAB28_human def: "Ras-related protein Rab-28 gene" [UniProtKB:P51157] xref: EMBL:AF498955 xref: EMBL:BC018067 xref: EMBL:BC035054 xref: EMBL:X94703 xref: HGNC:HGNC:9768 xref: UniGene:Hs.656060 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055459 ! RAB28_HUMAN relationship: codes_for CCO:B0057991 ! Q8WVF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019585 name: RAB2A_human def: "Ras-related protein Rab-2A gene" [UniProtKB:P61019] synonym: "RAB2" EXACT [UniProtKB:P61019] xref: EMBL:AF498930 xref: EMBL:BC008929 xref: EMBL:BT019695 xref: EMBL:M28213 xref: EMBL:X12953 xref: HGNC:HGNC:9763 xref: UniGene:Hs.369017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055602 ! RAB2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019586 name: RAB2B_human def: "Ras-related protein Rab-2B gene" [UniProtKB:Q8WUD1] xref: EMBL:AF091029 xref: EMBL:AF468652 xref: EMBL:AK296057 xref: EMBL:BC020839 xref: EMBL:BC066366 xref: HGNC:HGNC:20246 xref: UniGene:Hs.22399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056872 ! Q6NZ33_HUMAN relationship: codes_for CCO:B0057977 ! RAB2B_HUMAN relationship: codes_for CCO:B0059215 ! Q9UL31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019587 name: RAB30_human def: "Ras-related protein Rab-30 gene" [UniProtKB:Q15771] xref: EMBL:AF498956 xref: EMBL:BC014213 xref: EMBL:CR542106 xref: EMBL:U57092 xref: HGNC:HGNC:9770 xref: UniGene:Hs.40758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056108 ! RAB30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019588 name: RAB32_human def: "Ras-related protein Rab-32 gene" [UniProtKB:Q13637] xref: EMBL:AF498958 xref: EMBL:AL133539 xref: EMBL:BC015061 xref: EMBL:BT020016 xref: EMBL:U59878 xref: EMBL:U71127 xref: HGNC:HGNC:9772 xref: UniGene:Hs.287714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055936 ! RAB32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019589 name: RAB34_human def: "Ras-related protein Rab-34 gene" [UniProtKB:Q9BZG1] synonym: "RAB39" EXACT [UniProtKB:Q9BZG1] synonym: "RAH" EXACT [UniProtKB:Q9BZG1] xref: EMBL:AC010761 xref: EMBL:AF322067 xref: EMBL:AJ277106 xref: EMBL:AK027312 xref: EMBL:AK074689 xref: EMBL:BC016841 xref: EMBL:BC091510 xref: EMBL:BT006702 xref: HGNC:HGNC:16519 xref: UniGene:Hs.301853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054126 ! A8MYQ9_HUMAN relationship: codes_for CCO:B0058598 ! RAB34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019590 name: RAB35_human def: "Ras-related protein Rab-35 gene" [UniProtKB:Q15286] synonym: "RAB1C" EXACT [UniProtKB:Q15286] synonym: "RAY" EXACT [UniProtKB:Q15286] xref: EMBL:AC004812 xref: EMBL:AF498960 xref: EMBL:BC015931 xref: EMBL:BT020024 xref: EMBL:CR536486 xref: EMBL:CR541683 xref: EMBL:X79781 xref: HGNC:HGNC:9774 xref: UniGene:Hs.524788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056054 ! RAB35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019591 name: RAB36_human def: "Ras-related protein Rab-36 gene" [UniProtKB:O95755] xref: EMBL:AB023061 xref: EMBL:AF133588 xref: EMBL:AY336745 xref: EMBL:BC104989 xref: EMBL:BC104991 xref: EMBL:CR456553 xref: HGNC:HGNC:9775 xref: UniGene:Hs.369557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054792 ! RAB36_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019592 name: RAB37_human def: "Ras-related protein Rab-37 gene" [UniProtKB:Q96AX2] xref: EMBL:AC064805 xref: EMBL:AK054846 xref: EMBL:AK098068 xref: EMBL:AK127073 xref: EMBL:AK290202 xref: EMBL:BC016615 xref: EMBL:BC040547 xref: EMBL:CH471099 xref: HGNC:HGNC:30268 xref: UniGene:Hs.592097 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054010 ! A8MSP2_HUMAN relationship: codes_for CCO:B0054023 ! A8MTC6_HUMAN relationship: codes_for CCO:B0054047 ! A8MUU7_HUMAN relationship: codes_for CCO:B0054096 ! A8MXF5_HUMAN relationship: codes_for CCO:B0054129 ! A8MYT0_HUMAN relationship: codes_for CCO:B0054143 ! A8MZI4_HUMAN relationship: codes_for CCO:B0057357 ! Q8IWA7_HUMAN relationship: codes_for CCO:B0058157 ! RAB37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019593 name: RAB3A_human def: "Ras-related protein Rab-3A gene" [UniProtKB:P20336] xref: EMBL:AC068499 xref: EMBL:AF157806 xref: EMBL:AF157807 xref: EMBL:AF157808 xref: EMBL:AF157809 xref: EMBL:AF254795 xref: EMBL:AF498931 xref: EMBL:BC011782 xref: EMBL:M28210 xref: HGNC:HGNC:9777 xref: UniGene:Hs.27744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055116 ! RAB3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019594 name: RAB3B_human def: "Ras-related protein Rab-3B gene" [UniProtKB:P20337] xref: EMBL:AF498932 xref: EMBL:AL445685 xref: EMBL:AL589663 xref: EMBL:BC005035 xref: EMBL:M28214 xref: HGNC:HGNC:9778 xref: UniGene:Hs.123072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055117 ! RAB3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019595 name: RAB3C_human def: "Ras-related protein Rab-3C gene" [UniProtKB:Q96E17] xref: EMBL:AC034250 xref: EMBL:AY026936 xref: EMBL:BC013033 xref: HGNC:HGNC:30269 xref: UniGene:Hs.482173 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054013 ! A8MSV0_HUMAN relationship: codes_for CCO:B0058200 ! RAB3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019596 name: RAB3D_human def: "Ras-related protein Rab-3D gene" [UniProtKB:O95716] synonym: "GOV" EXACT [UniProtKB:O95716] synonym: "RAB16" EXACT [UniProtKB:O95716] xref: EMBL:AF081353 xref: EMBL:AF498933 xref: EMBL:BC016471 xref: HGNC:HGNC:9779 xref: UniGene:Hs.655274 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054785 ! RAB3D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019597 name: RAB41_human def: "Ras-related protein Rab-41 gene" [UniProtKB:Q5JT25] xref: EMBL:AL357752 xref: HGNC:HGNC:18293 xref: UniGene:Hs.276327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056481 ! RAB41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019598 name: RAB42_human def: "Putative Ras-related protein Rab-42 gene" [UniProtKB:Q8N4Z0] xref: EMBL:AL513497 xref: EMBL:BC033175 xref: HGNC:HGNC:28702 xref: UniGene:Hs.652321 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057468 ! RAB42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019599 name: RAB43_human def: "Ras-related protein Rab-43 gene" [UniProtKB:Q86YS6] synonym: "RAB41" EXACT [UniProtKB:Q86YS6] xref: EMBL:AY166852 xref: EMBL:BC062319 xref: HGNC:HGNC:19983 xref: UniGene:Hs.546542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057311 ! RAB43_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019600 name: RAB44_human def: "Ras-related protein Rab-44 gene" [UniProtKB:Q7Z6P3] xref: EMBL:Z85996 xref: HGNC:HGNC:21068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057199 ! RAB44_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019601 name: RAB4B_human def: "Ras-related protein Rab-4B gene" [UniProtKB:P61018] synonym: "PP1596" EXACT [UniProtKB:P61018] xref: EMBL:AF087861 xref: EMBL:AF165522 xref: EMBL:AF217985 xref: EMBL:AF498935 xref: EMBL:BC033081 xref: EMBL:BC046927 xref: EMBL:CH471126 xref: HGNC:HGNC:9782 xref: UniGene:Hs.631539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055601 ! RAB4B_HUMAN relationship: codes_for CCO:B0056913 ! Q6PIK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019602 name: RAB6A_human def: "Ras-related protein Rab-6A gene" [UniProtKB:P20340] synonym: "RAB6" EXACT [UniProtKB:P20340] xref: EMBL:AF119836 xref: EMBL:AF130122 xref: EMBL:AF130986 xref: EMBL:AF198616 xref: EMBL:AF498939 xref: EMBL:AF498941 xref: EMBL:AK057157 xref: EMBL:BC003617 xref: EMBL:BC068486 xref: EMBL:BC096818 xref: EMBL:BT019698 xref: EMBL:M28212 xref: HGNC:HGNC:9786 xref: UniGene:Hs.12152 xref: UniGene:Hs.503222 xref: UniGene:Hs.535586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055118 ! RAB6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019603 name: RAB6B_human def: "Ras-related protein Rab-6B gene" [UniProtKB:Q9NRW1] xref: EMBL:AF166492 xref: EMBL:AF498940 xref: EMBL:BC002510 xref: EMBL:BT007263 xref: HGNC:HGNC:14902 xref: UniGene:Hs.12152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058905 ! RAB6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019604 name: RAB6C_human def: "Ras-related protein Rab-6C gene" [UniProtKB:Q9H0N0] synonym: "WTH3" EXACT [UniProtKB:Q9H0N0] xref: EMBL:AB232598 xref: EMBL:AC073869 xref: EMBL:AC079776 xref: EMBL:AF124200 xref: EMBL:AF309646 xref: EMBL:AL136727 xref: EMBL:BC120999 xref: EMBL:CH471058 xref: EMBL:CH471103 xref: EMBL:CR533469 xref: HGNC:HGNC:16525 xref: UniGene:Hs.591552 xref: UniGene:Hs.645670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056364 ! Q53S08_HUMAN relationship: codes_for CCO:B0058655 ! RAB6C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019605 name: RAB7A_human def: "Ras-related protein Rab-7a gene" [UniProtKB:P51149] synonym: "RAB7" EXACT [UniProtKB:P51149] xref: EMBL:AF050175 xref: EMBL:AF498942 xref: EMBL:AK000826 xref: EMBL:AK290721 xref: EMBL:BC008721 xref: EMBL:CH471052 xref: EMBL:U44104 xref: EMBL:X93499 xref: HGNC:HGNC:9788 xref: UniGene:Hs.15738 xref: UniGene:Hs.644809 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055457 ! RAB7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019606 name: RAB7B_human def: "Ras-related protein Rab-7b gene" [UniProtKB:Q96AH8] xref: EMBL:AY094596 xref: EMBL:BC017092 xref: HGNC:HGNC:30513 xref: UniGene:Hs.534612 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058153 ! RAB7B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019607 name: RAB7L1_human def: "Ras-related protein Rab-7L1 gene" [UniProtKB:O14966] xref: EMBL:BC002585 xref: EMBL:D84488 xref: HGNC:HGNC:9789 xref: UniGene:Hs.115325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054394 ! RAB7L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019608 name: RAB9A_human def: "Ras-related protein Rab-9A gene" [UniProtKB:P51151] synonym: "RAB9" EXACT [UniProtKB:P51151] xref: EMBL:AF498944 xref: EMBL:BC017265 xref: EMBL:CR450362 xref: EMBL:U44103 xref: HGNC:HGNC:9792 xref: UniGene:Hs.495704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055458 ! RAB9A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019609 name: RAB9B_human def: "Ras-related protein Rab-9B gene" [UniProtKB:Q9NP90] synonym: "RAB9L" EXACT [UniProtKB:Q9NP90] xref: EMBL:AB036693 xref: EMBL:AL139228 xref: EMBL:BC093756 xref: EMBL:BC093758 xref: HGNC:HGNC:14090 xref: UniGene:Hs.522736 xref: UniGene:Hs.679046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058841 ! RAB9B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019610 name: RBJ_human def: "Rab and DnaJ domain-containing protein gene" [UniProtKB:Q9NZQ0] synonym: "RABJS" EXACT [UniProtKB:Q9NZQ0] xref: EMBL:AF178983 xref: EMBL:AL137731 xref: EMBL:AY094594 xref: EMBL:BC034049 xref: EMBL:BK001284 xref: EMBL:CH471053 xref: HGNC:HGNC:30290 xref: UniGene:Hs.434993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059009 ! RABJ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019611 name: RABL3_human def: "Rab-like protein 3 gene" [UniProtKB:Q5HYI8] xref: EMBL:AK293085 xref: EMBL:BC020832 xref: EMBL:BX647559 xref: EMBL:BX647593 xref: EMBL:BX647664 xref: EMBL:CH471052 xref: HGNC:HGNC:18072 xref: UniGene:Hs.444360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056444 ! RABL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019612 name: RAC2_human def: "Ras-related C3 botulinum toxin substrate 2 precursor gene" [UniProtKB:P15153] xref: EMBL:AF498965 xref: EMBL:BC001485 xref: EMBL:BT006919 xref: EMBL:CH471095 xref: EMBL:CR456555 xref: EMBL:M29871 xref: EMBL:M64595 xref: EMBL:Z82188 xref: HGNC:HGNC:9802 xref: UniGene:Hs.517601 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025802 ! RAC2_HUMAN relationship: codes_for CCO:B0054205 ! B1AH77_HUMAN relationship: codes_for CCO:B0054206 ! B1AH78_HUMAN relationship: codes_for CCO:B0054207 ! B1AH80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019613 name: RAC3_human def: "Ras-related C3 botulinum toxin substrate 3 precursor gene" [UniProtKB:P60763] xref: EMBL:AF008591 xref: EMBL:AF498966 xref: EMBL:BC009605 xref: EMBL:BC015197 xref: EMBL:BT019443 xref: HGNC:HGNC:9803 xref: UniGene:Hs.45002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025814 ! RAC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019614 name: RRAD_human def: "GTP-binding protein RAD gene" [UniProtKB:P55042] synonym: "RAD" EXACT [UniProtKB:P55042] xref: EMBL:BC011645 xref: EMBL:BC057815 xref: EMBL:L24564 xref: HGNC:HGNC:10446 xref: UniGene:Hs.1027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055524 ! RAD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019615 name: AGER_human def: "Advanced glycosylation end product-specific receptor precursor gene" [UniProtKB:Q15109] synonym: "RAGE" EXACT [UniProtKB:Q15109] xref: EMBL:AB036432 xref: EMBL:AF208289 xref: EMBL:AJ133822 xref: EMBL:AL662830 xref: EMBL:AL662884 xref: EMBL:AL845464 xref: EMBL:BC020669 xref: EMBL:D28769 xref: EMBL:M91211 xref: EMBL:U89336 xref: HGNC:HGNC:320 xref: UniGene:Hs.700564 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056043 ! RAGE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019616 name: GPRC5A_human def: "Retinoic acid-induced protein 3 gene" [UniProtKB:Q8NFJ5] synonym: "GPCR5A" EXACT [UniProtKB:Q8NFJ5] synonym: "RAI3" EXACT [UniProtKB:Q8NFJ5] synonym: "RAIG1" EXACT [UniProtKB:Q8NFJ5] xref: EMBL:AF095448 xref: EMBL:AF506289 xref: EMBL:AK001761 xref: EMBL:BC003665 xref: HGNC:HGNC:9836 xref: UniGene:Hs.631733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057603 ! RAI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019617 name: RASIP1_human def: "Ras-interacting protein 1 gene" [UniProtKB:Q5U651] xref: EMBL:AY378097 xref: EMBL:BC028614 xref: HGNC:HGNC:24716 xref: UniGene:Hs.233955 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056639 ! RAIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019618 name: RALA_human def: "Ras-related protein Ral-A precursor gene" [UniProtKB:P11233] synonym: "RAL" EXACT [UniProtKB:P11233] xref: EMBL:AC004837 xref: EMBL:AF493910 xref: EMBL:BC039858 xref: EMBL:M29893 xref: EMBL:X15014 xref: HGNC:HGNC:9839 xref: UniGene:Hs.6906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054988 ! RALA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019619 name: RALB_human def: "Ras-related protein Ral-B precursor gene" [UniProtKB:P11234] xref: EMBL:AF493911 xref: EMBL:AK127675 xref: EMBL:BC018163 xref: EMBL:BT006953 xref: EMBL:CH471103 xref: EMBL:M35416 xref: EMBL:X15015 xref: HGNC:HGNC:9840 xref: UniGene:Hs.469820 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054989 ! RALB_HUMAN relationship: codes_for CCO:B0057049 ! Q6ZS74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019620 name: RAMP1_human def: "Receptor activity-modifying protein 1 precursor gene" [UniProtKB:O60894] xref: EMBL:AC016776 xref: EMBL:AJ001014 xref: EMBL:AY265457 xref: EMBL:BC000548 xref: HGNC:HGNC:9843 xref: UniGene:Hs.471783 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054587 ! RAMP1_HUMAN relationship: codes_for CCO:B0056365 ! Q53SN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019621 name: RAPH1_human def: "Ras-associated and pleckstrin homology domains-containing protein 1 gene" [UniProtKB:Q70E73] synonym: "ALS2CR18" EXACT [UniProtKB:Q70E73] synonym: "ALS2CR9" EXACT [UniProtKB:Q70E73] synonym: "KIAA1681" EXACT [UniProtKB:Q70E73] synonym: "LPD" EXACT [UniProtKB:Q70E73] synonym: "PREL2" EXACT [UniProtKB:Q70E73] synonym: "RMO1" EXACT [UniProtKB:Q70E73] xref: EMBL:AB051468 xref: EMBL:AB053311 xref: EMBL:AC018891 xref: EMBL:AJ584699 xref: EMBL:AY494951 xref: EMBL:AY523977 xref: EMBL:AY523978 xref: HGNC:HGNC:14436 xref: UniGene:Hs.471162 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057092 ! RAPH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019622 name: RASA2_human def: "Ras GTPase-activating protein 2 gene" [UniProtKB:Q15283] synonym: "GAP1M" EXACT [UniProtKB:Q15283] synonym: "RASGAP" EXACT [UniProtKB:Q15283] xref: EMBL:AF115573 xref: EMBL:D78155 xref: EMBL:D78156 xref: EMBL:D82880 xref: EMBL:D82881 xref: HGNC:HGNC:9872 xref: UniGene:Hs.655941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056052 ! RASA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019623 name: RASA3_human def: "Ras GTPase-activating protein 3 gene" [UniProtKB:Q14644] xref: EMBL:AK289746 xref: EMBL:AL161774 xref: EMBL:BC038456 xref: EMBL:BC047242 xref: EMBL:BX537329 xref: EMBL:X89399 xref: HGNC:HGNC:20331 xref: UniGene:Hs.655219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054007 ! A8MSJ7_HUMAN relationship: codes_for CCO:B0056008 ! RASA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019624 name: RASD1_human def: "Dexamethasone-induced Ras-related protein 1 precursor gene" [UniProtKB:Q9Y272] synonym: "AGS1" EXACT [UniProtKB:Q9Y272] synonym: "DEXRAS1" EXACT [UniProtKB:Q9Y272] xref: EMBL:AF069506 xref: EMBL:AF153192 xref: EMBL:AF172846 xref: EMBL:AF222979 xref: EMBL:AF262018 xref: EMBL:AF498923 xref: EMBL:BC018041 xref: HGNC:HGNC:15828 xref: UniGene:Hs.25829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059295 ! RASD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019625 name: RASEF_human def: "RAS and EF-hand domain-containing protein gene" [UniProtKB:Q8IZ41] synonym: "RAB45" EXACT [UniProtKB:Q8IZ41] xref: EMBL:AK056176 xref: EMBL:AL499602 xref: EMBL:BC023566 xref: EMBL:CH471089 xref: HGNC:HGNC:26464 xref: UniGene:Hs.657750 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057398 ! RASEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019626 name: ERAS_human def: "GTPase ERas precursor gene" [UniProtKB:Q7Z444] synonym: "HRAS2" EXACT [UniProtKB:Q7Z444] synonym: "HRASP" EXACT [UniProtKB:Q7Z444] xref: EMBL:AB093575 xref: EMBL:BC101642 xref: EMBL:BC101644 xref: HGNC:HGNC:5174 xref: UniGene:Hs.447330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057161 ! RASE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019627 name: RASSF7_human def: "Ras association domain-containing protein 7 gene" [UniProtKB:Q02833] synonym: "C11orf13" EXACT [UniProtKB:Q02833] synonym: "HRC1" EXACT [UniProtKB:Q02833] xref: EMBL:BC106921 xref: EMBL:M91083 xref: HGNC:HGNC:1166 xref: UniGene:Hs.72925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055716 ! RASF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019628 name: RASSF10_human def: "Ras association domain-containing protein 10 gene" [UniProtKB:A6NK89] xref: EMBL:AC084859 xref: HGNC:HGNC:33984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053880 ! RASFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019629 name: RASAL1_human def: "RasGAP-activating-like protein 1 gene" [UniProtKB:O95294] synonym: "RASAL" EXACT [UniProtKB:O95294] xref: EMBL:AF086713 xref: EMBL:AL136672 xref: EMBL:BC014420 xref: EMBL:BC093724 xref: HGNC:HGNC:9873 xref: UniGene:Hs.528693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054747 ! RASL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019630 name: RASA4_human def: "Ras GTPase-activating protein 4 gene" [UniProtKB:O43374] synonym: "CAPRI" EXACT [UniProtKB:O43374] synonym: "GAPL" EXACT [UniProtKB:O43374] synonym: "KIAA0538" EXACT [UniProtKB:O43374] xref: EMBL:AB011110 xref: EMBL:AC004084 xref: EMBL:AC105052 xref: EMBL:AY029206 xref: EMBL:BC113663 xref: HGNC:HGNC:23181 xref: UniGene:Hs.696339 xref: UniGene:Hs.700609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054478 ! RASL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019631 name: RASL12_human def: "Ras-like protein family member 12 gene" [UniProtKB:Q9NYN1] synonym: "RIS" EXACT [UniProtKB:Q9NYN1] xref: EMBL:AF233588 xref: EMBL:BC053734 xref: EMBL:CH471082 xref: HGNC:HGNC:30289 xref: UniGene:Hs.27018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058966 ! RASLC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019632 name: MRAS_human def: "Ras-related protein M-Ras precursor gene" [UniProtKB:O14807] synonym: "RRAS3" EXACT [UniProtKB:O14807] xref: EMBL:AC022497 xref: EMBL:AF022080 xref: EMBL:AF043938 xref: EMBL:AF493918 xref: EMBL:BT020057 xref: HGNC:HGNC:7227 xref: UniGene:Hs.527021 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054379 ! RASM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019633 name: RAX2_human def: "Retina and anterior neural fold homeobox protein 2 gene" [UniProtKB:Q96IS3] synonym: "QRX" EXACT [UniProtKB:Q96IS3] synonym: "RAXL1" EXACT [UniProtKB:Q96IS3] xref: EMBL:AC005777 xref: EMBL:AY211277 xref: EMBL:BC007284 xref: EMBL:BC018709 xref: EMBL:BC032512 xref: HGNC:HGNC:18286 xref: UniGene:Hs.532691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058232 ! RAX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019634 name: RABL4_human def: "Putative GTP-binding protein RAY-like gene" [UniProtKB:Q9BW83] synonym: "RAYL" EXACT [UniProtKB:Q9BW83] xref: EMBL:AB209424 xref: EMBL:AL022729 xref: EMBL:BC000566 xref: EMBL:BT006815 xref: EMBL:CR456558 xref: EMBL:Z80897 xref: HGNC:HGNC:18626 xref: UniGene:Hs.415172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053906 ! A6NMI4_HUMAN relationship: codes_for CCO:B0054203 ! B1AH57_HUMAN relationship: codes_for CCO:B0054204 ! B1AH58_HUMAN relationship: codes_for CCO:B0058530 ! RAYL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019635 name: RAB27B_human def: "Ras-related protein Rab-27B gene" [UniProtKB:O00194] xref: EMBL:AF329499 xref: EMBL:AF498954 xref: EMBL:BC027474 xref: EMBL:U57093 xref: HGNC:HGNC:9767 xref: UniGene:Hs.25318 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054297 ! RB27B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019636 name: RAB33A_human def: "Ras-related protein Rab-33A gene" [UniProtKB:Q14088] synonym: "RABS10" EXACT [UniProtKB:Q14088] xref: EMBL:AF498959 xref: EMBL:AL139234 xref: EMBL:BC001157 xref: EMBL:BC009996 xref: EMBL:BT007038 xref: EMBL:D14889 xref: HGNC:HGNC:9773 xref: UniGene:Hs.654356 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055956 ! RB33A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019637 name: RAB33B_human def: "Ras-related protein Rab-33B gene" [UniProtKB:Q9H082] xref: EMBL:AC114743 xref: EMBL:AF350420 xref: EMBL:AL136904 xref: EMBL:BC111977 xref: HGNC:HGNC:16075 xref: UniGene:Hs.591679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058649 ! RB33B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019638 name: RAB39_human def: "Ras-related protein Rab-39A gene" [UniProtKB:Q14964] synonym: "RAB39A" EXACT [UniProtKB:Q14964] xref: EMBL:BC028064 xref: EMBL:X99962 xref: HGNC:HGNC:16521 xref: UniGene:Hs.354906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056028 ! RB39A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019639 name: RAB39B_human def: "Ras-related protein Rab-39B gene" [UniProtKB:Q96DA2] xref: EMBL:AL356738 xref: EMBL:AL834460 xref: EMBL:AY052478 xref: EMBL:BC009714 xref: HGNC:HGNC:16499 xref: UniGene:Hs.632832 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058191 ! RB39B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019640 name: RAB40A_human def: "Ras-related protein Rab-40A gene" [UniProtKB:Q8WXH6] xref: EMBL:AB232637 xref: EMBL:AF132748 xref: EMBL:AF422143 xref: EMBL:BC074854 xref: EMBL:BC074855 xref: EMBL:BC113501 xref: EMBL:BC117232 xref: EMBL:Z69733 xref: HGNC:HGNC:18283 xref: UniGene:Hs.27453 xref: UniGene:Hs.702260 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058021 ! RB40A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019641 name: RAB40B_human def: "Ras-related protein Rab-40B gene" [UniProtKB:Q12829] synonym: "SEC4L" EXACT [UniProtKB:Q12829] xref: EMBL:BC018039 xref: EMBL:U05227 xref: HGNC:HGNC:18284 xref: UniGene:Hs.484068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055845 ! RB40B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019642 name: RAB40C_human def: "Ras-related protein Rab-40C gene" [UniProtKB:Q96S21] synonym: "RARL" EXACT [UniProtKB:Q96S21] synonym: "RASL8C" EXACT [UniProtKB:Q96S21] xref: EMBL:AE006464 xref: EMBL:Z84479 xref: EMBL:Z98883 xref: HGNC:HGNC:18285 xref: UniGene:Hs.459630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058384 ! RB40C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019643 name: RAB40AL_human def: "Ras-related protein Rab-40A-like gene" [UniProtKB:P0C0E4] synonym: "RLGP" EXACT [UniProtKB:P0C0E4] xref: EMBL:BC101169 xref: EMBL:BC101170 xref: EMBL:BC101171 xref: EMBL:BC101172 xref: EMBL:Z95624 xref: HGNC:HGNC:25410 xref: UniGene:Hs.449517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054953 ! RB40L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019644 name: ERC1_human def: "ELKS/RAB6-interacting/CAST family member 1 gene" [UniProtKB:Q8IUD2] synonym: "ELKS" EXACT [UniProtKB:Q8IUD2] synonym: "KIAA1081" EXACT [UniProtKB:Q8IUD2] synonym: "RAB6IP2" EXACT [UniProtKB:Q8IUD2] xref: EMBL:AB015617 xref: EMBL:AB029004 xref: EMBL:AB053468 xref: EMBL:AB053469 xref: EMBL:AB053470 xref: EMBL:AB053471 xref: EMBL:AK000148 xref: EMBL:AK092201 xref: EMBL:BC068006 xref: HGNC:HGNC:17072 xref: UniGene:Hs.658200 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057322 ! RB6I2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019645 name: RBAK_human def: "RB-associated KRAB zinc finger protein gene" [UniProtKB:Q9NYW8] synonym: "ZNF769" EXACT [UniProtKB:Q9NYW8] xref: EMBL:AC008167 xref: EMBL:AC092032 xref: EMBL:AF226869 xref: EMBL:AK293069 xref: EMBL:CH471144 xref: HGNC:HGNC:17680 xref: UniGene:Hs.592827 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058985 ! RBAK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019646 name: RBM15_human def: "Putative RNA-binding protein 15 gene" [UniProtKB:Q96T37] synonym: "OTT" EXACT [UniProtKB:Q96T37] xref: EMBL:AF364035 xref: EMBL:AF368062 xref: EMBL:AF368063 xref: EMBL:AF368064 xref: EMBL:AJ297259 xref: EMBL:AJ303089 xref: EMBL:AJ303090 xref: EMBL:AK022541 xref: EMBL:AK025596 xref: EMBL:AL355488 xref: EMBL:BC006397 xref: EMBL:BC062316 xref: HGNC:HGNC:14959 xref: UniGene:Hs.435947 xref: UniGene:Hs.654688 xref: UniGene:Hs.705574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058400 ! RBM15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019647 name: RBM39_human def: "RNA-binding protein 39 gene" [UniProtKB:Q14498] synonym: "HCC1" EXACT [UniProtKB:Q14498] synonym: "RNPC2" EXACT [UniProtKB:Q14498] xref: EMBL:AL357374 xref: EMBL:BC141835 xref: EMBL:L10910 xref: EMBL:L10911 xref: HGNC:HGNC:15923 xref: UniGene:Hs.282901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055987 ! RBM39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019648 name: RBM9_human def: "RNA-binding protein 9 gene" [UniProtKB:O43251] synonym: "FOX2" EXACT [UniProtKB:O43251] synonym: "HRNBP2" EXACT [UniProtKB:O43251] synonym: "RTA" EXACT [UniProtKB:O43251] xref: EMBL:AF229058 xref: EMBL:AK055213 xref: EMBL:AK291460 xref: EMBL:AL009266 xref: EMBL:AL049748 xref: EMBL:AL079295 xref: EMBL:AM419009 xref: EMBL:AY072786 xref: EMBL:AY960684 xref: EMBL:BC013115 xref: EMBL:BC025281 xref: EMBL:CR456559 xref: EMBL:DQ778625 xref: HGNC:HGNC:9906 xref: UniGene:Hs.282998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054463 ! RBM9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019649 name: RALBP1_human def: "RalA-binding protein 1 gene" [UniProtKB:Q15311] synonym: "RLIP1" EXACT [UniProtKB:Q15311] synonym: "RLIP76" EXACT [UniProtKB:Q15311] xref: EMBL:BC013126 xref: EMBL:L42542 xref: HGNC:HGNC:9841 xref: UniGene:Hs.528993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056057 ! RBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019650 name: RBPJL_human def: "Recombining binding protein suppressor of hairless-like protein gene" [UniProtKB:Q9UBG7] synonym: "RBPL" EXACT [UniProtKB:Q9UBG7] synonym: "RBPSUHL" EXACT [UniProtKB:Q9UBG7] xref: EMBL:AB024964 xref: EMBL:AB026048 xref: EMBL:AB027710 xref: EMBL:AL021578 xref: HGNC:HGNC:13761 xref: UniGene:Hs.248217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059073 ! RBPJL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019651 name: LMO1_human def: "Rhombotin-1 gene" [UniProtKB:P25800] synonym: "RBTN1" EXACT [UniProtKB:P25800] synonym: "RHOM1" EXACT [UniProtKB:P25800] synonym: "TTG1" EXACT [UniProtKB:P25800] xref: EMBL:AC091013 xref: EMBL:AJ277662 xref: EMBL:BC069673 xref: EMBL:BC069752 xref: EMBL:BC069793 xref: EMBL:BC096056 xref: EMBL:BC096057 xref: EMBL:M26682 xref: HGNC:HGNC:6641 xref: UniGene:Hs.654426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055186 ! RBTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019652 name: RNF7_human def: "RING-box protein 2 gene" [UniProtKB:Q9UBF6] synonym: "RBX2" EXACT [UniProtKB:Q9UBF6] synonym: "ROC2" EXACT [UniProtKB:Q9UBF6] synonym: "SAG" EXACT [UniProtKB:Q9UBF6] xref: EMBL:AF092878 xref: EMBL:AF142060 xref: EMBL:AF164679 xref: EMBL:AF312226 xref: EMBL:BC005966 xref: EMBL:BC008627 xref: EMBL:BT007348 xref: HGNC:HGNC:10070 xref: UniGene:Hs.134623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059071 ! RBX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019653 name: RCAN1_human def: "Calcipressin-1 gene" [UniProtKB:P53805] synonym: "ADAPT78" EXACT [UniProtKB:P53805] synonym: "CSP1" EXACT [UniProtKB:P53805] synonym: "DSC1" EXACT [UniProtKB:P53805] synonym: "DSCR1" EXACT [UniProtKB:P53805] xref: EMBL:AF400429 xref: EMBL:AK092184 xref: EMBL:AP000326 xref: EMBL:AP000327 xref: EMBL:AY325903 xref: EMBL:BC002864 xref: EMBL:BT007363 xref: EMBL:CH471079 xref: EMBL:CR456878 xref: EMBL:U28833 xref: EMBL:U53821 xref: EMBL:U85265 xref: EMBL:U85266 xref: EMBL:U85267 xref: HGNC:HGNC:3040 xref: UniGene:Hs.282326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055512 ! RCAN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019654 name: RCAN2_human def: "Calcipressin-2 gene" [UniProtKB:Q14206] synonym: "DSCR1L1" EXACT [UniProtKB:Q14206] synonym: "ZAKI4" EXACT [UniProtKB:Q14206] xref: EMBL:AL359633 xref: EMBL:AL390741 xref: EMBL:AY034085 xref: EMBL:AY034086 xref: EMBL:BC038509 xref: EMBL:CH471081 xref: EMBL:D83407 xref: HGNC:HGNC:3041 xref: UniGene:Hs.440168 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055971 ! RCAN2_HUMAN relationship: codes_for CCO:B0057305 ! Q86YJ0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019655 name: RCAN3_human def: "Calcipressin-3 gene" [UniProtKB:Q9UKA8] synonym: "DSCR1L2" EXACT [UniProtKB:Q9UKA8] xref: EMBL:AF176116 xref: EMBL:AF176117 xref: EMBL:AL034582 xref: EMBL:BC035854 xref: HGNC:HGNC:3042 xref: UniGene:Hs.656799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059190 ! RCAN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019656 name: EBAG9_human def: "Receptor-binding cancer antigen expressed on SiSo cells gene" [UniProtKB:O00559] synonym: "RCAS1" EXACT [UniProtKB:O00559] xref: EMBL:AB007619 xref: EMBL:AF006265 xref: EMBL:BC005249 xref: EMBL:BC017729 xref: EMBL:BC022506 xref: EMBL:CR456984 xref: HGNC:HGNC:3123 xref: UniGene:Hs.409368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054331 ! RCAS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019657 name: RQCD1_human def: "Cell differentiation protein RCD1 homolog gene" [UniProtKB:Q92600] synonym: "RCD1" EXACT [UniProtKB:Q92600] xref: EMBL:BC007102 xref: EMBL:CH471063 xref: EMBL:D87957 xref: HGNC:HGNC:10445 xref: UniGene:Hs.148767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058069 ! RCD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019658 name: RCL_human def: "c-Myc-responsive protein Rcl gene" [UniProtKB:O43598] synonym: "C6orf108" EXACT [UniProtKB:O43598] xref: EMBL:AF040105 xref: EMBL:AL133375 xref: EMBL:BC011683 xref: HGNC:HGNC:21218 xref: UniGene:Hs.109752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054497 ! RCL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019659 name: RCOR1_human def: "REST corepressor 1 gene" [UniProtKB:Q9UKL0] synonym: "KIAA0071" EXACT [UniProtKB:Q9UKL0] synonym: "RCOR" EXACT [UniProtKB:Q9UKL0] xref: EMBL:AF155595 xref: EMBL:BC051003 xref: EMBL:BC064495 xref: EMBL:D31888 xref: HGNC:HGNC:17441 xref: UniGene:Hs.510521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059194 ! RCOR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019660 name: RCOR2_human def: "REST corepressor 2 gene" [UniProtKB:Q8IZ40] xref: EMBL:AP003780 xref: EMBL:BC010608 xref: EMBL:BC023587 xref: HGNC:HGNC:27455 xref: UniGene:Hs.98788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057397 ! RCOR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019661 name: RCOR3_human def: "REST corepressor 3 gene" [UniProtKB:Q9P2K3] synonym: "KIAA1343" EXACT [UniProtKB:Q9P2K3] xref: EMBL:AB037764 xref: EMBL:AK001738 xref: EMBL:AL590101 xref: EMBL:AL611964 xref: EMBL:BC031608 xref: HGNC:HGNC:25594 xref: UniGene:Hs.696152 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059058 ! RCOR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019662 name: RCVRN_human def: "Recoverin gene" [UniProtKB:P35243] synonym: "RCV1" EXACT [UniProtKB:P35243] xref: EMBL:AB001838 xref: EMBL:BC001720 xref: EMBL:S43855 xref: EMBL:S45545 xref: EMBL:S62028 xref: HGNC:HGNC:9937 xref: UniGene:Hs.80539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055281 ! RECO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019663 name: REG1A_human def: "Lithostathine-1-alpha precursor gene" [UniProtKB:P05451] synonym: "PSPS" EXACT [UniProtKB:P05451] synonym: "REG" EXACT [UniProtKB:P05451] xref: EMBL:AF172331 xref: EMBL:BC005350 xref: EMBL:J05412 xref: EMBL:M18963 xref: EMBL:M27189 xref: EMBL:M27190 xref: HGNC:HGNC:9951 xref: UniGene:Hs.4158 xref: UniGene:Hs.49407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054900 ! REG1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019664 name: REG1B_human def: "Lithostathine-1-beta precursor gene" [UniProtKB:P48304] synonym: "REGL" EXACT [UniProtKB:P48304] xref: EMBL:BC027895 xref: EMBL:D16816 xref: EMBL:D17291 xref: EMBL:L08010 xref: HGNC:HGNC:9952 xref: UniGene:Hs.4158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055401 ! REG1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019665 name: REG3A_human def: "Regenerating islet-derived protein 3 alpha precursor gene" [UniProtKB:Q06141] synonym: "HIP" EXACT [UniProtKB:Q06141] synonym: "PAP" EXACT [UniProtKB:Q06141] synonym: "PAP1" EXACT [UniProtKB:Q06141] xref: EMBL:BC036776 xref: EMBL:D13510 xref: EMBL:L15533 xref: EMBL:M84337 xref: EMBL:S51768 xref: EMBL:X68641 xref: HGNC:HGNC:8601 xref: UniGene:Hs.567312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055766 ! REG3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019666 name: RELN_human def: "Reelin precursor gene" [UniProtKB:P78509] xref: EMBL:AC000121 xref: EMBL:AC002067 xref: EMBL:AC005064 xref: EMBL:AC005101 xref: EMBL:AC006316 xref: EMBL:AC006981 xref: EMBL:AC073208 xref: EMBL:U79716 xref: HGNC:HGNC:9957 xref: UniGene:Hs.655654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055647 ! RELN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019667 name: REL_human def: "C-Rel proto-oncogene protein gene" [UniProtKB:Q04864] xref: EMBL:BC117191 xref: EMBL:DQ314888 xref: EMBL:M11595 xref: EMBL:X75042 xref: HGNC:HGNC:9954 xref: UniGene:Hs.631886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055737 ! REL_HUMAN relationship: codes_for CCO:B0056187 ! Q17RU2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019668 name: REM1_human def: "GTP-binding protein REM 1 gene" [UniProtKB:O75628] synonym: "GES" EXACT [UniProtKB:O75628] synonym: "REM" EXACT [UniProtKB:O75628] xref: EMBL:AF084465 xref: EMBL:AF152863 xref: EMBL:AL121751 xref: EMBL:BC039813 xref: HGNC:HGNC:15922 xref: UniGene:Hs.247729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054659 ! REM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019669 name: REM2_human def: "GTP-binding protein REM 2 gene" [UniProtKB:Q8IYK8] xref: EMBL:AK096283 xref: EMBL:BC035663 xref: HGNC:HGNC:20248 xref: UniGene:Hs.444911 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057389 ! REM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019670 name: REN_human def: "Renin precursor gene" [UniProtKB:P00797] xref: EMBL:AL592114 xref: EMBL:AL592146 xref: EMBL:AY436324 xref: EMBL:BC033474 xref: EMBL:BC047752 xref: EMBL:L00064 xref: EMBL:L00065 xref: EMBL:L00066 xref: EMBL:L00067 xref: EMBL:L00068 xref: EMBL:L00069 xref: EMBL:L00070 xref: EMBL:L00071 xref: EMBL:L00072 xref: EMBL:L00073 xref: EMBL:M10030 xref: EMBL:M10128 xref: EMBL:M10150 xref: EMBL:M10151 xref: EMBL:M10152 xref: EMBL:M13253 xref: EMBL:M15410 xref: EMBL:M26440 xref: EMBL:M26899 xref: EMBL:M26900 xref: EMBL:M26901 xref: HGNC:HGNC:9958 xref: UniGene:Hs.3210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054828 ! RENI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019671 name: ATP6AP2_human def: "Renin receptor precursor gene" [UniProtKB:O75787] synonym: "ATP6IP2" EXACT [UniProtKB:O75787] synonym: "CAPER" EXACT [UniProtKB:O75787] synonym: "ELDF10" EXACT [UniProtKB:O75787] synonym: "HT028" EXACT [UniProtKB:O75787] synonym: "MSTP009" EXACT [UniProtKB:O75787] synonym: "PSEC0072" EXACT [UniProtKB:O75787] xref: EMBL:AF109363 xref: EMBL:AF248966 xref: EMBL:AF291814 xref: EMBL:AK075382 xref: EMBL:AL049929 xref: EMBL:AY038990 xref: EMBL:AY429341 xref: EMBL:BC010395 xref: EMBL:BC084541 xref: EMBL:Y17975 xref: HGNC:HGNC:18305 xref: UniGene:Hs.700634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054667 ! RENR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019672 name: REPIN1_human def: "Replication initiator 1 gene" [UniProtKB:Q9BWE0] synonym: "RIP60" EXACT [UniProtKB:Q9BWE0] synonym: "ZNF464" EXACT [UniProtKB:Q9BWE0] xref: EMBL:AC005586 xref: EMBL:AF201303 xref: EMBL:AJ245553 xref: EMBL:BC000363 xref: EMBL:BC001760 xref: HGNC:HGNC:17922 xref: UniGene:Hs.647086 xref: UniGene:Hs.655734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058531 ! REPI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019673 name: REPS2_human def: "RalBP1-associated Eps domain-containing protein 2 gene" [UniProtKB:Q8NFH8] synonym: "POB1" EXACT [UniProtKB:Q8NFH8] xref: EMBL:AF010233 xref: EMBL:AF511533 xref: EMBL:AF512951 xref: HGNC:HGNC:9963 xref: UniGene:Hs.186810 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057602 ! REPS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019674 name: DPF2_human def: "Zinc finger protein ubi-d4 gene" [UniProtKB:Q92785] synonym: "REQ" EXACT [UniProtKB:Q92785] synonym: "UBID4" EXACT [UniProtKB:Q92785] xref: EMBL:AF001433 xref: EMBL:AY220877 xref: EMBL:BC014889 xref: EMBL:BT006718 xref: EMBL:U43920 xref: EMBL:U94585 xref: HGNC:HGNC:9964 xref: UniGene:Hs.13495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058094 ! REQU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019675 name: RERGL_human def: "Ras-related and estrogen-regulated growth inhibitor-like protein gene" [UniProtKB:Q9H628] xref: EMBL:AK026308 xref: EMBL:BC042888 xref: EMBL:CH471094 xref: HGNC:HGNC:26213 xref: UniGene:Hs.115497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058732 ! RERGL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019676 name: RERG_human def: "Ras-related and estrogen-regulated growth inhibitor gene" [UniProtKB:Q96A58] xref: EMBL:AF339750 xref: EMBL:BC007997 xref: HGNC:HGNC:15980 xref: UniGene:Hs.199487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058147 ! RERG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019677 name: REST_human def: "RE1-silencing transcription factor gene" [UniProtKB:Q13127] synonym: "NRSF" EXACT [UniProtKB:Q13127] synonym: "XBR" EXACT [UniProtKB:Q13127] xref: EMBL:AB209750 xref: EMBL:BC038985 xref: EMBL:U13877 xref: EMBL:U13879 xref: EMBL:U22314 xref: EMBL:U22680 xref: HGNC:HGNC:9966 xref: UniGene:Hs.631513 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055876 ! REST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019678 name: RETNLB_human def: "Resistin-like beta precursor gene" [UniProtKB:Q9BQ08] synonym: "CCRG" EXACT [UniProtKB:Q9BQ08] synonym: "FIZZ2" EXACT [UniProtKB:Q9BQ08] synonym: "HXCP2" EXACT [UniProtKB:Q9BQ08] synonym: "RETNL2" EXACT [UniProtKB:Q9BQ08] synonym: "UNQ408/PRO770" EXACT [UniProtKB:Q9BQ08] xref: EMBL:AF290873 xref: EMBL:AF323084 xref: EMBL:AF323921 xref: EMBL:AF352731 xref: EMBL:AY358655 xref: EMBL:BC069318 xref: EMBL:BC113502 xref: EMBL:BC113528 xref: HGNC:HGNC:20388 xref: UniGene:Hs.307047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058474 ! RETNB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019679 name: RET_human def: "Proto-oncogene tyrosine-protein kinase receptor ret precursor gene" [UniProtKB:P07949] synonym: "CDHF12" EXACT [UniProtKB:P07949] xref: EMBL:AJ297349 xref: EMBL:M16029 xref: EMBL:M31213 xref: EMBL:X12949 xref: EMBL:X15262 xref: EMBL:X15786 xref: HGNC:HGNC:9967 xref: UniGene:Hs.350321 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017344 ! RET_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019680 name: REV1_human def: "DNA repair protein REV1 gene" [UniProtKB:Q9UBZ9] synonym: "REV1L" EXACT [UniProtKB:Q9UBZ9] xref: EMBL:AB047646 xref: EMBL:AC018690 xref: EMBL:AF151538 xref: EMBL:AF206019 xref: EMBL:AF357886 xref: EMBL:AJ131720 xref: EMBL:AK002087 xref: HGNC:HGNC:14060 xref: UniGene:Hs.443077 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059092 ! REV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019681 name: REXO4_human def: "RNA exonuclease 4 gene" [UniProtKB:Q9GZR2] synonym: "PMC2" EXACT [UniProtKB:Q9GZR2] synonym: "XPMC2H" EXACT [UniProtKB:Q9GZR2] xref: EMBL:AF273304 xref: EMBL:AF295774 xref: EMBL:AK025493 xref: EMBL:AL136894 xref: EMBL:AL158826 xref: EMBL:BC009274 xref: HGNC:HGNC:12820 xref: UniGene:Hs.438409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058634 ! REXO4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019682 name: RPA4_human def: "Replication protein A 30 kDa subunit gene" [UniProtKB:Q13156] xref: EMBL:AF494047 xref: EMBL:BC069791 xref: EMBL:BC069808 xref: EMBL:BC069824 xref: EMBL:BC104013 xref: EMBL:BC104014 xref: EMBL:U24186 xref: EMBL:Z86061 xref: HGNC:HGNC:30305 xref: UniGene:Hs.659349 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055880 ! RFA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019683 name: NPVF_human def: "FMRFamide-related peptides precursor gene" [UniProtKB:Q9HCQ7] synonym: "C7orf9" EXACT [UniProtKB:Q9HCQ7] synonym: "RFRP" EXACT [UniProtKB:Q9HCQ7] xref: EMBL:AB040290 xref: EMBL:AC004129 xref: EMBL:AF330057 xref: EMBL:AF440392 xref: EMBL:AF440393 xref: EMBL:AF440394 xref: EMBL:AF440395 xref: HGNC:HGNC:13782 xref: UniGene:Hs.60473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058817 ! RFRP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019684 name: RFX2_human def: "DNA-binding protein RFX2 gene" [UniProtKB:P48378] xref: EMBL:BC028579 xref: EMBL:X76091 xref: HGNC:HGNC:9983 xref: UniGene:Hs.465709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028074 ! RFX2_HUMAN relationship: codes_for CCO:B0028084 ! Q8SNA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019685 name: RFX3_human def: "Transcription factor RFX3 gene" [UniProtKB:P48380] xref: EMBL:AL133549 xref: EMBL:AL354941 xref: EMBL:AL365202 xref: EMBL:BC022191 xref: EMBL:BC067778 xref: EMBL:X76092 xref: HGNC:HGNC:9984 xref: UniGene:Hs.136829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028072 ! Q5JTM4_HUMAN relationship: codes_for CCO:B0028073 ! RFX3_HUMAN relationship: codes_for CCO:B0028088 ! Q5JTM3_HUMAN relationship: codes_for CCO:B0054159 ! A9Z1Z2_HUMAN relationship: codes_for CCO:B0054264 ! B1ANP5_HUMAN relationship: codes_for CCO:B0054265 ! B1ANP6_HUMAN relationship: codes_for CCO:B0054266 ! B1ANP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019686 name: RFX4_human def: "Transcription factor RFX4 gene" [UniProtKB:Q33E94] xref: EMBL:AB044245 xref: EMBL:AB095365 xref: EMBL:AB095366 xref: EMBL:AB195784 xref: EMBL:AB195785 xref: EMBL:AF332192 xref: EMBL:AK074913 xref: EMBL:AK291445 xref: EMBL:AL833921 xref: EMBL:AY102009 xref: EMBL:BC028582 xref: EMBL:BC030644 xref: EMBL:CH471054 xref: HGNC:HGNC:9985 xref: UniGene:Hs.388827 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028183 ! A8K5Y0_HUMAN relationship: codes_for CCO:B0056242 ! RFX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019687 name: RFX5_human def: "DNA-binding protein RFX5 gene" [UniProtKB:P48382] xref: EMBL:AL391069 xref: EMBL:BC017471 xref: EMBL:X85786 xref: HGNC:HGNC:9986 xref: UniGene:Hs.632472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053718 ! A2A3Q3_HUMAN relationship: codes_for CCO:B0053719 ! A2A3Q4_HUMAN relationship: codes_for CCO:B0053720 ! A2A3Q5_HUMAN relationship: codes_for CCO:B0053929 ! A6PVW1_HUMAN relationship: codes_for CCO:B0053930 ! A6PVW2_HUMAN relationship: codes_for CCO:B0053931 ! A6PVW3_HUMAN relationship: codes_for CCO:B0053932 ! A6PVW4_HUMAN relationship: codes_for CCO:B0053933 ! A6PVW5_HUMAN relationship: codes_for CCO:B0053934 ! A6PVW7_HUMAN relationship: codes_for CCO:B0055402 ! RFX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019688 name: RFX6_human def: "DNA-binding protein RFX6 gene" [UniProtKB:Q8HWS3] synonym: "RFXDC1" EXACT [UniProtKB:Q8HWS3] xref: EMBL:AL355272 xref: EMBL:BC039248 xref: EMBL:CH471051 xref: HGNC:HGNC:21478 xref: UniGene:Hs.352276 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0061983 ! RFX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019689 name: RFXANK_human def: "DNA-binding protein RFXANK gene" [UniProtKB:O14593] synonym: "ANKRA1" EXACT [UniProtKB:O14593] synonym: "RFXB" EXACT [UniProtKB:O14593] xref: EMBL:AC003110 xref: EMBL:AF077196 xref: EMBL:AF094760 xref: EMBL:AF105427 xref: EMBL:AF105428 xref: EMBL:BC114563 xref: EMBL:CH471106 xref: EMBL:CR542199 xref: HGNC:HGNC:9987 xref: UniGene:Hs.153629 xref: UniGene:Hs.296776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054355 ! RFXK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019690 name: RGL4_human def: "Ral-GDS-related protein gene" [UniProtKB:Q8IZJ4] synonym: "RGR" EXACT [UniProtKB:Q8IZJ4] xref: EMBL:AP000347 xref: EMBL:AY101396 xref: EMBL:BC101109 xref: EMBL:BC101110 xref: HGNC:HGNC:31911 xref: UniGene:Hs.658997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016358 ! Q495L7_HUMAN relationship: codes_for CCO:B0056282 ! Q3ZCN2_HUMAN relationship: codes_for CCO:B0057408 ! RGDSR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019691 name: RASGEF1A_human def: "Ras-GEF domain-containing family member 1A gene" [UniProtKB:Q8N9B8] xref: EMBL:AC068707 xref: EMBL:AK095136 xref: EMBL:BC022548 xref: HGNC:HGNC:24246 xref: UniGene:Hs.125293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053859 ! A6NIB0_HUMAN relationship: codes_for CCO:B0057535 ! RGF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019692 name: RASGEF1B_human def: "Ras-GEF domain-containing family member 1B gene" [UniProtKB:Q0VAM2] synonym: "GPIG4" EXACT [UniProtKB:Q0VAM2] xref: EMBL:AC006287 xref: EMBL:AC093618 xref: EMBL:AC093747 xref: EMBL:AK056257 xref: EMBL:BC036784 xref: EMBL:BC121003 xref: EMBL:BC121004 xref: HGNC:HGNC:24881 xref: UniGene:Hs.591696 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055822 ! RGF1B_HUMAN relationship: codes_for CCO:B0057461 ! Q8N437_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019693 name: RASGEF1C_human def: "Ras-GEF domain-containing family member 1C gene" [UniProtKB:Q8N431] xref: EMBL:AF449764 xref: EMBL:AK093160 xref: EMBL:BC036802 xref: EMBL:CH471165 xref: HGNC:HGNC:27400 xref: UniGene:Hs.190559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057460 ! RGF1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019694 name: RGL2_human def: "Ral guanine nucleotide dissociation stimulator-like 2 gene" [UniProtKB:O15211] synonym: "RAB2L" EXACT [UniProtKB:O15211] xref: EMBL:AL050259 xref: EMBL:AL662820 xref: EMBL:AL662827 xref: EMBL:BC032681 xref: EMBL:BC040989 xref: EMBL:BX000343 xref: EMBL:CH471081 xref: EMBL:CR759786 xref: EMBL:CR759817 xref: EMBL:D85757 xref: EMBL:U68142 xref: EMBL:Z97184 xref: HGNC:HGNC:9769 xref: UniGene:Hs.509622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054416 ! RGL2_HUMAN relationship: codes_for CCO:B0056314 ! Q4G0R5_HUMAN relationship: codes_for CCO:B0058113 ! Q92942_HUMAN relationship: codes_for CCO:B0063431 ! Q5STK0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019695 name: RGL3_human def: "Ral guanine nucleotide dissociation stimulator-like 3 gene" [UniProtKB:Q3MIN7] xref: EMBL:BC014426 xref: EMBL:BC101756 xref: EMBL:BC111958 xref: HGNC:HGNC:30282 xref: UniGene:Hs.375142 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016367 ! RGL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019696 name: RGMB_human def: "RGM domain family member B precursor gene" [UniProtKB:Q6NW40] xref: EMBL:AK074887 xref: EMBL:BC067736 xref: HGNC:HGNC:26896 xref: UniGene:Hs.526902 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056863 ! RGMB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019697 name: RGNEF_human def: "Rho-guanine nucleotide exchange factor gene" [UniProtKB:Q8N1W1] synonym: "KIAA1998" EXACT [UniProtKB:Q8N1W1] xref: EMBL:AB082529 xref: EMBL:AC008387 xref: EMBL:AC026702 xref: EMBL:AC091868 xref: EMBL:AC093283 xref: EMBL:AK025470 xref: EMBL:AK025816 xref: EMBL:AK094713 xref: EMBL:BC012946 xref: UniGene:Hs.482521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057433 ! RGNEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019698 name: RGN_human def: "Regucalcin gene" [UniProtKB:Q15493] synonym: "SMP30" EXACT [UniProtKB:Q15493] xref: EMBL:AB028125 xref: EMBL:AB032064 xref: EMBL:AK223360 xref: EMBL:AL513366 xref: EMBL:BC050371 xref: EMBL:BC073173 xref: EMBL:D31815 xref: HGNC:HGNC:9989 xref: UniGene:Hs.77854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056070 ! RGN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019699 name: RASGRF1_human def: "Ras-specific guanine nucleotide-releasing factor 1 gene" [UniProtKB:Q13972] synonym: "CDC25" EXACT [UniProtKB:Q13972] synonym: "GNRP" EXACT [UniProtKB:Q13972] synonym: "GRF1" EXACT [UniProtKB:Q13972] xref: EMBL:BC040275 xref: EMBL:CH471136 xref: EMBL:L26584 xref: EMBL:M91815 xref: EMBL:S62035 xref: HGNC:HGNC:9875 xref: UniGene:Hs.591111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055954 ! RGRF1_HUMAN relationship: codes_for CCO:B0057328 ! Q8IUU5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019700 name: RASGRF2_human def: "Ras-specific guanine nucleotide-releasing factor 2 gene" [UniProtKB:O14827] synonym: "GRF2" EXACT [UniProtKB:O14827] xref: EMBL:AF023130 xref: EMBL:AF181250 xref: EMBL:BC126112 xref: EMBL:CH471084 xref: HGNC:HGNC:9876 xref: UniGene:Hs.162129 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054381 ! RGRF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019701 name: RGR_human def: "RPE-retinal G protein-coupled receptor gene" [UniProtKB:P47804] xref: EMBL:AC022389 xref: EMBL:BC011349 xref: EMBL:U14910 xref: EMBL:U14911 xref: EMBL:U15785 xref: EMBL:U15786 xref: EMBL:U15787 xref: EMBL:U15788 xref: EMBL:U15789 xref: EMBL:U15790 xref: HGNC:HGNC:9990 xref: UniGene:Hs.1544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053886 ! A6NKK7_HUMAN relationship: codes_for CCO:B0053921 ! A6NNY4_HUMAN relationship: codes_for CCO:B0055386 ! RGR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019702 name: RGS11_human def: "Regulator of G-protein signaling 11 gene" [UniProtKB:O94810] xref: EMBL:AB016929 xref: EMBL:AC004754 xref: EMBL:AE006463 xref: EMBL:AF035153 xref: EMBL:AF035154 xref: EMBL:BC040504 xref: EMBL:CH471112 xref: EMBL:Z69667 xref: HGNC:HGNC:9993 xref: UniGene:Hs.65756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054700 ! RGS11_HUMAN relationship: codes_for CCO:B0056323 ! Q4TT72_HUMAN relationship: codes_for CCO:B0057359 ! Q8IWC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019703 name: RGS22_human def: "Regulator of G-protein signaling 22 gene" [UniProtKB:Q8NE09] xref: EMBL:AL117544 xref: EMBL:BC036665 xref: EMBL:BC047060 xref: EMBL:BC092411 xref: HGNC:HGNC:24499 xref: UniGene:Hs.120021 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057587 ! RGS22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019704 name: RGS6_human def: "Regulator of G-protein signaling 6 gene" [UniProtKB:P49758] xref: EMBL:AC004828 xref: EMBL:AC005157 xref: EMBL:AC005226 xref: EMBL:AC005227 xref: EMBL:AC005477 xref: EMBL:AC005533 xref: EMBL:AC005857 xref: EMBL:AC005993 xref: EMBL:AF073920 xref: EMBL:AF073921 xref: EMBL:AF107619 xref: EMBL:AF107620 xref: EMBL:AF156932 xref: EMBL:AF465711 xref: EMBL:AF465712 xref: EMBL:AF465713 xref: EMBL:AF465714 xref: EMBL:AF465715 xref: EMBL:AF465716 xref: EMBL:AF465717 xref: EMBL:AF465718 xref: EMBL:AF465719 xref: EMBL:AF465720 xref: EMBL:AF465721 xref: EMBL:AF465722 xref: EMBL:AF465723 xref: EMBL:AF465724 xref: EMBL:AF465725 xref: EMBL:AF465726 xref: EMBL:AF465727 xref: EMBL:L40394 xref: HGNC:HGNC:10002 xref: UniGene:Hs.509872 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055433 ! RGS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019705 name: RGS7_human def: "Regulator of G-protein signaling 7 gene" [UniProtKB:P49802] xref: EMBL:AF090116 xref: EMBL:AF090117 xref: EMBL:AF493930 xref: EMBL:AF493931 xref: EMBL:AL359764 xref: EMBL:AL365184 xref: EMBL:AL512307 xref: EMBL:AL590682 xref: EMBL:AY587875 xref: EMBL:CH471098 xref: EMBL:U32439 xref: HGNC:HGNC:10003 xref: UniGene:Hs.655739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055438 ! RGS7_HUMAN relationship: codes_for CCO:B0056568 ! Q5T3H4_HUMAN relationship: codes_for CCO:B0056569 ! Q5T3H5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019706 name: RGS9_human def: "Regulator of G-protein signaling 9 gene" [UniProtKB:O75916] xref: EMBL:AF071476 xref: EMBL:AF073710 xref: EMBL:AF178056 xref: EMBL:AF178057 xref: EMBL:AF178058 xref: EMBL:AF178059 xref: EMBL:AF178060 xref: EMBL:AF178061 xref: EMBL:AF178062 xref: EMBL:AF178063 xref: EMBL:AF178064 xref: EMBL:AF178065 xref: EMBL:AF178066 xref: EMBL:AF178067 xref: EMBL:AF178068 xref: EMBL:AF178069 xref: EMBL:AF178070 xref: EMBL:AF178071 xref: EMBL:AF178072 xref: EMBL:AF493932 xref: EMBL:AF493933 xref: EMBL:AK290535 xref: EMBL:AY585190 xref: EMBL:AY585191 xref: EMBL:CH471099 xref: HGNC:HGNC:10004 xref: UniGene:Hs.664380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053962 ! A8K3C0_HUMAN relationship: codes_for CCO:B0054678 ! RGS9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019707 name: RHBDL1_human def: "Rhomboid-related protein 1 gene" [UniProtKB:O75783] synonym: "RHBDL" EXACT [UniProtKB:O75783] xref: EMBL:AE006464 xref: EMBL:AJ272344 xref: EMBL:BC120874 xref: EMBL:BC120875 xref: EMBL:Y17108 xref: HGNC:HGNC:10007 xref: UniGene:Hs.137572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054666 ! RHBL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019708 name: RHBDL2_human def: "Rhomboid-related protein 2 gene" [UniProtKB:Q9NX52] xref: EMBL:AK000442 xref: EMBL:AL139260 xref: EMBL:AY126343 xref: EMBL:BC013103 xref: HGNC:HGNC:16083 xref: UniGene:Hs.524626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058948 ! RHBL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019709 name: RHBDL3_human def: "Rhomboid-related protein 3 gene" [UniProtKB:P58872] synonym: "RHBDL4" EXACT [UniProtKB:P58872] synonym: "VRHO" EXACT [UniProtKB:P58872] xref: EMBL:AC026620 xref: EMBL:AJ313480 xref: EMBL:BC100975 xref: HGNC:HGNC:16502 xref: UniGene:Hs.655027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055573 ! RHBL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019710 name: RHOBTB1_human def: "Rho-related BTB domain-containing protein 1 gene" [UniProtKB:O94844] synonym: "KIAA0740" EXACT [UniProtKB:O94844] xref: EMBL:AB018283 xref: EMBL:AK075129 xref: EMBL:BC032848 xref: EMBL:BC041791 xref: HGNC:HGNC:18738 xref: UniGene:Hs.148670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054704 ! RHBT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019711 name: RHOBTB2_human def: "Rho-related BTB domain-containing protein 2 gene" [UniProtKB:Q9BYZ6] synonym: "DBC2" EXACT [UniProtKB:Q9BYZ6] synonym: "KIAA0717" EXACT [UniProtKB:Q9BYZ6] xref: EMBL:AB018260 xref: EMBL:AF315385 xref: EMBL:AY009093 xref: EMBL:BC034917 xref: HGNC:HGNC:18756 xref: UniGene:Hs.372688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058588 ! RHBT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019712 name: RASD2_human def: "GTP-binding protein Rhes precursor gene" [UniProtKB:Q96D21] synonym: "TEM2" EXACT [UniProtKB:Q96D21] xref: EMBL:AF279143 xref: EMBL:AL022334 xref: EMBL:BC013419 xref: EMBL:CR456477 xref: HGNC:HGNC:18229 xref: UniGene:Hs.474711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058189 ! RHES_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019713 name: RHOXF2B_human def: "Rhox homeobox family member 2B gene" [UniProtKB:P0C7M4] xref: EMBL:AC005023 xref: EMBL:AL590524 xref: HGNC:HGNC:33519 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054963 ! RHF2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019714 name: ARHGAP1_human def: "Rho GTPase-activating protein 1 gene" [UniProtKB:Q07960] synonym: "CDC42GAP" EXACT [UniProtKB:Q07960] synonym: "RHOGAP1" EXACT [UniProtKB:Q07960] xref: EMBL:BC018118 xref: EMBL:U02570 xref: EMBL:Z23024 xref: HGNC:HGNC:673 xref: UniGene:Hs.138860 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055787 ! RHG01_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019715 name: ARHGAP4_human def: "Rho GTPase-activating protein 4 gene" [UniProtKB:P98171] synonym: "KIAA0131" EXACT [UniProtKB:P98171] synonym: "RGC1" EXACT [UniProtKB:P98171] synonym: "RHOGAP4" EXACT [UniProtKB:P98171] xref: EMBL:BC023626 xref: EMBL:BC052303 xref: EMBL:CH471172 xref: EMBL:D50921 xref: EMBL:X78817 xref: HGNC:HGNC:674 xref: UniGene:Hs.433291 xref: UniGene:Hs.522818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055675 ! RHG04_HUMAN relationship: codes_for CCO:B0056917 ! Q6PJ34_HUMAN relationship: codes_for CCO:B0057258 ! Q86UY3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019716 name: ARHGAP6_human def: "Rho GTPase-activating protein 6 gene" [UniProtKB:O43182] synonym: "RHOGAP6" EXACT [UniProtKB:O43182] xref: EMBL:AF012272 xref: EMBL:AF022212 xref: EMBL:AF117067 xref: EMBL:AF177663 xref: EMBL:AF177665 xref: HGNC:HGNC:676 xref: UniGene:Hs.435291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054455 ! RHG06_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019717 name: ARHGAP9_human def: "Rho GTPase-activating protein 9 gene" [UniProtKB:Q9BRR9] xref: EMBL:AB030239 xref: EMBL:AB051853 xref: EMBL:AL713803 xref: EMBL:BC006107 xref: EMBL:BC011820 xref: HGNC:HGNC:14130 xref: UniGene:Hs.437126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058496 ! RHG09_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019718 name: ARHGAP10_human def: "Rho GTPase-activating protein 10 gene" [UniProtKB:A1A4S6] synonym: "GRAF2" EXACT [UniProtKB:A1A4S6] xref: EMBL:AB050785 xref: EMBL:BC011920 xref: EMBL:BC109029 xref: EMBL:BC109030 xref: EMBL:BC126899 xref: EMBL:BC128055 xref: HGNC:HGNC:26099 xref: UniGene:Hs.368631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053705 ! RHG10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019719 name: ARHGAP17_human def: "Rho GTPase-activating protein 17 gene" [UniProtKB:Q68EM7] synonym: "MSTP066" EXACT [UniProtKB:Q68EM7] synonym: "MSTP110" EXACT [UniProtKB:Q68EM7] synonym: "RICH1" EXACT [UniProtKB:Q68EM7] xref: EMBL:AF163257 xref: EMBL:AF173885 xref: EMBL:AJ306731 xref: EMBL:AJ306732 xref: EMBL:AK001170 xref: EMBL:AK023281 xref: EMBL:AK027567 xref: EMBL:AK125358 xref: EMBL:AL833975 xref: EMBL:BC001241 xref: EMBL:BC080195 xref: HGNC:HGNC:18239 xref: UniGene:Hs.373793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019132 ! RHG17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019720 name: ARHGAP19_human def: "Rho GTPase-activating protein 19 gene" [UniProtKB:Q14CB8] xref: EMBL:AK074122 xref: EMBL:AK090447 xref: EMBL:AK093441 xref: EMBL:AL359385 xref: EMBL:AY336750 xref: EMBL:BC113888 xref: EMBL:BC114490 xref: EMBL:CR749412 xref: EMBL:DQ338460 xref: HGNC:HGNC:23724 xref: UniGene:Hs.80305 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056033 ! RHG19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019721 name: ARHGAP21_human def: "Rho GTPase-activating protein 21 gene" [UniProtKB:Q5T5U3] synonym: "ARHGAP10" EXACT [UniProtKB:Q5T5U3] synonym: "KIAA1424" EXACT [UniProtKB:Q5T5U3] xref: EMBL:AB037845 xref: EMBL:AF480466 xref: EMBL:AL355979 xref: EMBL:AL392104 xref: EMBL:AL834495 xref: EMBL:BC022931 xref: EMBL:BX537570 xref: HGNC:HGNC:23725 xref: UniGene:Hs.524195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056477 ! Q5JSD4_HUMAN relationship: codes_for CCO:B0056478 ! Q5JSD8_HUMAN relationship: codes_for CCO:B0056584 ! RHG21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019722 name: ARHGAP22_human def: "Rho GTPase-activating protein 22 gene" [UniProtKB:Q7Z5H3] synonym: "RHOGAP2" EXACT [UniProtKB:Q7Z5H3] xref: EMBL:AC016397 xref: EMBL:AK127586 xref: EMBL:AY324801 xref: EMBL:BC126444 xref: EMBL:U90908 xref: HGNC:HGNC:30320 xref: UniGene:Hs.655672 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053790 ! A6NDI7_HUMAN relationship: codes_for CCO:B0053868 ! A6NJ38_HUMAN relationship: codes_for CCO:B0057180 ! RHG22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019723 name: ARHGAP23_human def: "Rho GTPase-activating protein 23 gene" [UniProtKB:Q9P227] synonym: "KIAA1501" EXACT [UniProtKB:Q9P227] xref: EMBL:AB040934 xref: EMBL:AC115090 xref: HGNC:HGNC:29293 xref: UniGene:Hs.374446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059051 ! RHG23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019724 name: ARHGAP24_human def: "Rho GTPase-activating protein 24 gene" [UniProtKB:Q8N264] synonym: "FILGAP" EXACT [UniProtKB:Q8N264] xref: EMBL:AK091196 xref: EMBL:AK130576 xref: EMBL:AL136646 xref: EMBL:AY211925 xref: EMBL:BC047918 xref: EMBL:BC098580 xref: HGNC:HGNC:25361 xref: UniGene:Hs.444229 xref: UniGene:Hs.667822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057438 ! RHG24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019725 name: ARHGAP25_human def: "Rho GTPase-activating protein 25 gene" [UniProtKB:P42331] synonym: "KIAA0053" EXACT [UniProtKB:P42331] xref: EMBL:BC039591 xref: EMBL:D29642 xref: HGNC:HGNC:28951 xref: UniGene:Hs.531807 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055349 ! RHG25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019726 name: ARHGAP26_human def: "Rho GTPase-activating protein 26 gene" [UniProtKB:Q9UNA1] synonym: "GRAF" EXACT [UniProtKB:Q9UNA1] synonym: "KIAA0621" EXACT [UniProtKB:Q9UNA1] synonym: "OPHN1L" EXACT [UniProtKB:Q9UNA1] xref: EMBL:AB014521 xref: EMBL:AF141884 xref: EMBL:AJ309466 xref: EMBL:AJ309467 xref: EMBL:AJ309468 xref: EMBL:AJ309469 xref: EMBL:AJ309470 xref: EMBL:AJ309471 xref: EMBL:AJ309472 xref: EMBL:AJ309473 xref: EMBL:AJ309474 xref: EMBL:AJ309475 xref: EMBL:AJ309476 xref: EMBL:AJ309477 xref: EMBL:AJ309478 xref: EMBL:AJ309479 xref: EMBL:AJ309480 xref: EMBL:AJ309481 xref: EMBL:AJ309482 xref: EMBL:AJ309483 xref: EMBL:AJ309484 xref: EMBL:AJ309485 xref: EMBL:AJ309486 xref: EMBL:AJ309487 xref: EMBL:Y10388 xref: HGNC:HGNC:17073 xref: UniGene:Hs.654668 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059248 ! RHG26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019727 name: ARHGAP29_human def: "Rho GTPase-activating protein 29 gene" [UniProtKB:Q52LW3] synonym: "PARG1" EXACT [UniProtKB:Q52LW3] xref: EMBL:AB208873 xref: EMBL:AL162735 xref: EMBL:BC022483 xref: EMBL:BC067839 xref: EMBL:BC093741 xref: EMBL:BC093767 xref: EMBL:CH471097 xref: EMBL:U90920 xref: HGNC:HGNC:30207 xref: UniGene:Hs.483238 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056343 ! RHG29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019728 name: ARHGAP30_human def: "Rho GTPase-activating protein 30 gene" [UniProtKB:Q7Z6I6] xref: EMBL:AK160366 xref: EMBL:AL591806 xref: EMBL:BC043387 xref: EMBL:BC053688 xref: EMBL:BX537846 xref: HGNC:HGNC:27414 xref: UniGene:Hs.389374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057197 ! RHG30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019729 name: ARHGAP11A_human def: "Rho GTPase-activating protein 11A gene" [UniProtKB:Q6P4F7] synonym: "KIAA0013" EXACT [UniProtKB:Q6P4F7] xref: EMBL:BC039563 xref: EMBL:BC063444 xref: EMBL:D87717 xref: HGNC:HGNC:15783 xref: UniGene:Hs.591130 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056889 ! RHGBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019730 name: ARHGAP11B_human def: "Rho GTPase-activating protein 11B gene" [UniProtKB:Q3KRB8] xref: EMBL:BC105788 xref: HGNC:HGNC:15782 xref: UniGene:Hs.659621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056260 ! RHGBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019731 name: RHOD_human def: "Rho-related GTP-binding protein RhoD precursor gene" [UniProtKB:O00212] synonym: "ARHD" EXACT [UniProtKB:O00212] xref: EMBL:AF498973 xref: EMBL:BC001338 xref: EMBL:D85815 xref: HGNC:HGNC:670 xref: UniGene:Hs.15114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054300 ! RHOD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019732 name: RHOF_human def: "Rho-related GTP-binding protein RhoF precursor gene" [UniProtKB:Q9HBH0] synonym: "ARHF" EXACT [UniProtKB:Q9HBH0] synonym: "RIF" EXACT [UniProtKB:Q9HBH0] xref: EMBL:AF239923 xref: EMBL:AK000254 xref: EMBL:BC018208 xref: HGNC:HGNC:15703 xref: UniGene:Hs.524804 xref: UniGene:Hs.700608 xref: UniGene:Hs.703846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058784 ! RHOF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019733 name: RHOH_human def: "Rho-related GTP-binding protein RhoH precursor gene" [UniProtKB:Q15669] synonym: "ARHH" EXACT [UniProtKB:Q15669] synonym: "TTF" EXACT [UniProtKB:Q15669] xref: EMBL:AF498975 xref: EMBL:BC014261 xref: EMBL:Z35227 xref: HGNC:HGNC:686 xref: UniGene:Hs.654594 xref: UniGene:Hs.694951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056094 ! RHOH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019734 name: RHOJ_human def: "Rho-related GTP-binding protein RhoJ precursor gene" [UniProtKB:Q9H4E5] synonym: "ARHJ" EXACT [UniProtKB:Q9H4E5] synonym: "RASL7B" EXACT [UniProtKB:Q9H4E5] synonym: "RHOI" EXACT [UniProtKB:Q9H4E5] synonym: "TCL" EXACT [UniProtKB:Q9H4E5] xref: EMBL:AF309563 xref: EMBL:AF498977 xref: EMBL:AJ276567 xref: EMBL:AK027278 xref: EMBL:AK027351 xref: EMBL:BC062575 xref: HGNC:HGNC:688 xref: UniGene:Hs.656339 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058716 ! RHOJ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019735 name: RHOQ_human def: "Rho-related GTP-binding protein RhoQ precursor gene" [UniProtKB:P17081] synonym: "ARHQ" EXACT [UniProtKB:P17081] synonym: "RASL7A" EXACT [UniProtKB:P17081] synonym: "TC10" EXACT [UniProtKB:P17081] xref: EMBL:AC018682 xref: EMBL:AF498976 xref: EMBL:BC056154 xref: EMBL:BC065291 xref: EMBL:BC070485 xref: EMBL:BC093805 xref: EMBL:BC101806 xref: EMBL:M31470 xref: HGNC:HGNC:17736 xref: UniGene:Hs.701976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055081 ! RHOQ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019736 name: RHOU_human def: "Rho-related GTP-binding protein RhoU gene" [UniProtKB:Q7L0Q8] synonym: "ARHU" EXACT [UniProtKB:Q7L0Q8] synonym: "CDC42L1" EXACT [UniProtKB:Q7L0Q8] synonym: "G28K" EXACT [UniProtKB:Q7L0Q8] synonym: "SB128" EXACT [UniProtKB:Q7L0Q8] synonym: "WRCH1" EXACT [UniProtKB:Q7L0Q8] xref: EMBL:AB051826 xref: EMBL:AB074878 xref: EMBL:AB209511 xref: EMBL:AF211836 xref: EMBL:AF251701 xref: EMBL:AF282258 xref: EMBL:AF378087 xref: EMBL:AK289971 xref: EMBL:AL096776 xref: EMBL:BC040076 xref: EMBL:CH471098 xref: EMBL:DQ384420 xref: EMBL:DQ384421 xref: EMBL:DQ384422 xref: EMBL:DQ384423 xref: EMBL:DQ384424 xref: EMBL:DQ384425 xref: HGNC:HGNC:17794 xref: UniGene:Hs.647774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057113 ! RHOU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019737 name: RHOV_human def: "Rho-related GTP-binding protein RhoV gene" [UniProtKB:Q96L33] synonym: "ARHV" EXACT [UniProtKB:Q96L33] synonym: "WRCH2" EXACT [UniProtKB:Q96L33] xref: EMBL:AB079131 xref: EMBL:AY059636 xref: EMBL:BC019353 xref: EMBL:BC105020 xref: EMBL:BC105022 xref: EMBL:BC112945 xref: EMBL:CH471125 xref: HGNC:HGNC:18313 xref: UniGene:Hs.447901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055759 ! Q05D03_HUMAN relationship: codes_for CCO:B0058264 ! RHOV_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019738 name: RHPN1_human def: "Rhophilin-1 gene" [UniProtKB:Q8TCX5] synonym: "KIAA1929" EXACT [UniProtKB:Q8TCX5] xref: EMBL:AB067516 xref: EMBL:AY082588 xref: EMBL:BC025767 xref: HGNC:HGNC:19973 xref: UniGene:Hs.521912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057918 ! RHPN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019739 name: RHPN2_human def: "Rhophilin-2 gene" [UniProtKB:Q8IUC4] xref: EMBL:AF268032 xref: EMBL:AF423421 xref: EMBL:AJ347750 xref: EMBL:AK095001 xref: EMBL:AL831950 xref: EMBL:BC036447 xref: HGNC:HGNC:19974 xref: UniGene:Hs.466435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057320 ! RHPN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019740 name: RHOXF1_human def: "Rhox homeobox family member 1 gene" [UniProtKB:Q8NHV9] synonym: "OTEX" EXACT [UniProtKB:Q8NHV9] synonym: "PEPP1" EXACT [UniProtKB:Q8NHV9] xref: EMBL:AC005023 xref: EMBL:AY099086 xref: EMBL:BC069324 xref: EMBL:BC069529 xref: EMBL:BC103857 xref: EMBL:BC103858 xref: HGNC:HGNC:29993 xref: UniGene:Hs.644617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057877 ! RHXF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019741 name: RIC8B_human def: "Synembryn-B gene" [UniProtKB:Q9NVN3] xref: EMBL:AK001482 xref: EMBL:AK128102 xref: EMBL:AY221116 xref: EMBL:BC034220 xref: HGNC:HGNC:25555 xref: UniGene:Hs.131306 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058931 ! RIC8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019742 name: RICH2_human def: "Rho GTPase-activating protein RICH2 gene" [UniProtKB:Q17R89] synonym: "KIAA0672" EXACT [UniProtKB:Q17R89] xref: EMBL:AB014572 xref: EMBL:AC005274 xref: EMBL:AC005277 xref: EMBL:AY320403 xref: EMBL:BC117412 xref: EMBL:BC117416 xref: UniGene:Hs.499758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019135 ! RICH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019743 name: RIN2_human def: "Ras and Rab interactor 2 gene" [UniProtKB:Q8WYP3] synonym: "RASSF4" EXACT [UniProtKB:Q8WYP3] xref: EMBL:AB060339 xref: EMBL:AK094884 xref: EMBL:AL049538 xref: EMBL:AL132821 xref: EMBL:AL136924 xref: EMBL:BC128065 xref: EMBL:M37190 xref: HGNC:HGNC:18750 xref: UniGene:Hs.472270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053706 ! A1A4T0_HUMAN relationship: codes_for CCO:B0058047 ! RIN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019744 name: RIN3_human def: "Ras and Rab interactor 3 gene" [UniProtKB:Q8TB24] xref: EMBL:AB060338 xref: EMBL:AB081753 xref: EMBL:AK021762 xref: EMBL:AK026092 xref: EMBL:AK074176 xref: EMBL:AK090451 xref: EMBL:AL136332 xref: EMBL:AL159141 xref: EMBL:BC025248 xref: HGNC:HGNC:18751 xref: UniGene:Hs.326822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057896 ! RIN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019745 name: RIPPLY1_human def: "Protein ripply1 gene" [UniProtKB:Q0D2K3] xref: EMBL:AL591849 xref: EMBL:BC105691 xref: EMBL:BC105692 xref: EMBL:BC110436 xref: EMBL:BC127250 xref: EMBL:CH471120 xref: HGNC:HGNC:25117 xref: UniGene:Hs.334726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055809 ! RIPP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019746 name: RPAIN_human def: "RPA-interacting protein gene" [UniProtKB:Q86UA6] synonym: "RIP" EXACT [UniProtKB:Q86UA6] xref: EMBL:AY680654 xref: EMBL:AY680655 xref: EMBL:AY680656 xref: EMBL:AY680657 xref: EMBL:AY680658 xref: EMBL:AY680659 xref: EMBL:AY680660 xref: EMBL:AY775314 xref: EMBL:AY775315 xref: EMBL:AY775316 xref: EMBL:AY775317 xref: EMBL:AY775318 xref: EMBL:AY775319 xref: EMBL:AY775320 xref: EMBL:AY775321 xref: EMBL:AY775323 xref: EMBL:BC004451 xref: EMBL:BC046349 xref: EMBL:BC051849 xref: HGNC:HGNC:28641 xref: UniGene:Hs.462086 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057245 ! RIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019747 name: RIT2_human def: "GTP-binding protein Rit2 gene" [UniProtKB:Q99578] synonym: "RIN" EXACT [UniProtKB:Q99578] synonym: "ROC2" EXACT [UniProtKB:Q99578] xref: EMBL:AF493922 xref: EMBL:AY563951 xref: EMBL:BC018060 xref: EMBL:U71204 xref: EMBL:U78164 xref: EMBL:U78166 xref: EMBL:Y07565 xref: HGNC:HGNC:10017 xref: UniGene:Hs.464985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058426 ! RIT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019748 name: GRK1_human def: "Rhodopsin kinase precursor gene" [UniProtKB:Q15835] synonym: "RHOK" EXACT [UniProtKB:Q15835] xref: EMBL:AF019764 xref: EMBL:AK289912 xref: EMBL:L77496 xref: EMBL:L77497 xref: EMBL:L77498 xref: EMBL:L77499 xref: EMBL:L77500 xref: EMBL:L77501 xref: EMBL:L77502 xref: EMBL:L77503 xref: EMBL:U63973 xref: HGNC:HGNC:10013 xref: UniGene:Hs.103501 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054724 ! O95098_HUMAN relationship: codes_for CCO:B0056115 ! RK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019749 name: RXFP3_human def: "Relaxin-3 receptor 1 gene" [UniProtKB:Q9NSD7] synonym: "RLN3R1" EXACT [UniProtKB:Q9NSD7] synonym: "SALPR" EXACT [UniProtKB:Q9NSD7] xref: EMBL:AY236541 xref: EMBL:AY394501 xref: EMBL:BC113438 xref: EMBL:BC113440 xref: EMBL:D88437 xref: HGNC:HGNC:24883 xref: UniGene:Hs.170146 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058918 ! RL3R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019750 name: RXFP4_human def: "Relaxin-3 receptor 2 gene" [UniProtKB:Q8TDU9] synonym: "GPR100" EXACT [UniProtKB:Q8TDU9] synonym: "RLN3R2" EXACT [UniProtKB:Q8TDU9] xref: EMBL:AB065617 xref: EMBL:AB083593 xref: EMBL:AL355388 xref: EMBL:AY170824 xref: EMBL:AY288415 xref: EMBL:AY394502 xref: EMBL:BC101507 xref: EMBL:BC101509 xref: HGNC:HGNC:14666 xref: UniGene:Hs.449914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057940 ! RL3R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019751 name: RPL6_human def: "60S ribosomal protein L6 gene" [UniProtKB:Q02878] synonym: "TXREB1" EXACT [UniProtKB:Q02878] xref: EMBL:AB042820 xref: EMBL:BC004138 xref: EMBL:BC020679 xref: EMBL:BC032299 xref: EMBL:BC071912 xref: EMBL:BC104824 xref: EMBL:BC104826 xref: EMBL:D17554 xref: EMBL:S71022 xref: EMBL:X69391 xref: HGNC:HGNC:10362 xref: UniGene:Hs.528668 xref: UniGene:Hs.546283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055717 ! RL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019752 name: RLF_human def: "Zinc finger protein Rlf gene" [UniProtKB:Q13129] xref: EMBL:AL050341 xref: EMBL:AL356424 xref: EMBL:AL512599 xref: EMBL:AL929567 xref: EMBL:BC113666 xref: EMBL:U22377 xref: HGNC:HGNC:10025 xref: UniGene:Hs.205627 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055877 ! RLF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019753 name: MRPL12_human def: "39S ribosomal protein L12, mitochondrial precursor gene" [UniProtKB:P52815] synonym: "RPML12" EXACT [UniProtKB:P52815] xref: EMBL:AF059736 xref: EMBL:AF105278 xref: EMBL:BC002344 xref: EMBL:BC007497 xref: EMBL:X79865 xref: HGNC:HGNC:10378 xref: UniGene:Hs.109059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055501 ! RM12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019754 name: MRPL28_human def: "39S ribosomal protein L28, mitochondrial precursor gene" [UniProtKB:Q13084] synonym: "MAAT1" EXACT [UniProtKB:Q13084] xref: EMBL:AE006463 xref: EMBL:BC000507 xref: EMBL:BC000990 xref: EMBL:BT009857 xref: EMBL:U19796 xref: EMBL:Z97634 xref: HGNC:HGNC:14484 xref: UniGene:Hs.513230 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053731 ! A2IDC6_HUMAN relationship: codes_for CCO:B0053732 ! A2IDC7_HUMAN relationship: codes_for CCO:B0055871 ! RM28_HUMAN relationship: codes_for CCO:B0056321 ! Q4TT37_HUMAN relationship: codes_for CCO:B0056322 ! Q4TT38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019755 name: RMP_human def: "Unconventional prefoldin RPB5 interactor gene" [UniProtKB:O94763] synonym: "C19orf2" EXACT [UniProtKB:O94763] synonym: "NNX3" EXACT [UniProtKB:O94763] synonym: "URI" EXACT [UniProtKB:O94763] xref: EMBL:AB006572 xref: EMBL:AF091095 xref: EMBL:AK292170 xref: HGNC:HGNC:13236 xref: UniGene:Hs.466391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054697 ! RMP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019756 name: RNF128_human def: "E3 ubiquitin-protein ligase RNF128 precursor gene" [UniProtKB:Q8TEB7] synonym: "GRAIL" EXACT [UniProtKB:Q8TEB7] xref: EMBL:AF394689 xref: EMBL:AK027169 xref: EMBL:AK074264 xref: EMBL:AK126553 xref: EMBL:AL391315 xref: EMBL:AL606833 xref: EMBL:BC056677 xref: EMBL:BC063404 xref: HGNC:HGNC:21153 xref: UniGene:Hs.496542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057954 ! RN128_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019757 name: RNF139_human def: "RING finger protein 139 gene" [UniProtKB:Q8WU17] synonym: "TRC8" EXACT [UniProtKB:Q8WU17] xref: EMBL:AF064800 xref: EMBL:AF064801 xref: EMBL:BC021571 xref: EMBL:BC064636 xref: HGNC:HGNC:17023 xref: UniGene:Hs.632057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057974 ! RN139_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019758 name: RNF12_human def: "E3 ubiquitin-protein ligase RNF12 gene" [UniProtKB:Q9NVW2] synonym: "RLIM" EXACT [UniProtKB:Q9NVW2] xref: EMBL:AF155109 xref: EMBL:AJ271670 xref: EMBL:AK001334 xref: HGNC:HGNC:13429 xref: UniGene:Hs.653288 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058934 ! RNF12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019759 name: RNF14_human def: "E3 ubiquitin-protein ligase RNF14 gene" [UniProtKB:Q9UBS8] synonym: "ARA54" EXACT [UniProtKB:Q9UBS8] synonym: "HRIHFB2038" EXACT [UniProtKB:Q9UBS8] xref: EMBL:AB015333 xref: EMBL:AB022663 xref: EMBL:AC005740 xref: EMBL:AF060544 xref: EMBL:BC126185 xref: EMBL:CR456702 xref: HGNC:HGNC:10058 xref: UniGene:Hs.483616 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059083 ! RNF14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019760 name: RNASEH2A_human def: "Ribonuclease H2 subunit A gene" [UniProtKB:O75792] synonym: "RNASEHI" EXACT [UniProtKB:O75792] synonym: "RNHIA" EXACT [UniProtKB:O75792] xref: EMBL:BC011748 xref: EMBL:Z97029 xref: HGNC:HGNC:18518 xref: UniGene:Hs.532851 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021778 ! RNH2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019761 name: HNRNPAB_human def: "Heterogeneous nuclear ribonucleoprotein A/B gene" [UniProtKB:Q99729] synonym: "ABBP1" EXACT [UniProtKB:Q99729] synonym: "HNRPAB" EXACT [UniProtKB:Q99729] xref: EMBL:AK097657 xref: EMBL:BC001616 xref: EMBL:BC002625 xref: EMBL:BC004561 xref: EMBL:BC009359 xref: EMBL:BC036708 xref: EMBL:M65028 xref: EMBL:U76713 xref: HGNC:HGNC:5034 xref: UniGene:Hs.248746 xref: UniGene:Hs.591731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058447 ! ROAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019762 name: ROBO1_human def: "Roundabout homolog 1 precursor gene" [UniProtKB:Q9Y6N7] synonym: "DUTT1" EXACT [UniProtKB:Q9Y6N7] xref: EMBL:AF040990 xref: EMBL:BC001969 xref: EMBL:BX538319 xref: EMBL:Z95705 xref: HGNC:HGNC:10249 xref: UniGene:Hs.13640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059411 ! ROBO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019763 name: ROBO2_human def: "Roundabout homolog 2 precursor gene" [UniProtKB:Q9HCK4] synonym: "KIAA1568" EXACT [UniProtKB:Q9HCK4] xref: EMBL:AB046788 xref: EMBL:AF040991 xref: EMBL:BC064374 xref: HGNC:HGNC:10250 xref: UniGene:Hs.13305 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058810 ! ROBO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019764 name: ROBO4_human def: "Roundabout homolog 4 precursor gene" [UniProtKB:Q8WZ75] synonym: "UNQ421/PRO3674" EXACT [UniProtKB:Q8WZ75] xref: EMBL:AF361473 xref: EMBL:AK000805 xref: EMBL:AK025195 xref: EMBL:AK027852 xref: EMBL:AK074163 xref: EMBL:AY358083 xref: EMBL:BC039602 xref: EMBL:BC064643 xref: EMBL:BC111562 xref: EMBL:BC111748 xref: HGNC:HGNC:17985 xref: UniGene:Hs.524121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058051 ! ROBO4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019765 name: ROCK1_human def: "Rho-associated protein kinase 1 gene" [UniProtKB:Q13464] xref: EMBL:BC041849 xref: EMBL:EF445027 xref: EMBL:U43195 xref: HGNC:HGNC:10251 xref: UniGene:Hs.306307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054197 ! B0YJ91_HUMAN relationship: codes_for CCO:B0055910 ! ROCK1_HUMAN relationship: codes_for CCO:B0056303 ! Q49AA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019766 name: ROCK2_human def: "Rho-associated protein kinase 2 gene" [UniProtKB:O75116] synonym: "KIAA0619" EXACT [UniProtKB:O75116] xref: EMBL:AB014519 xref: EMBL:BC111801 xref: EMBL:D87931 xref: HGNC:HGNC:10252 xref: UniGene:Hs.591600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054602 ! ROCK2_HUMAN relationship: codes_for CCO:B0056034 ! Q14DU5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019767 name: MST1R_human def: "Macrophage-stimulating protein receptor precursor gene" [UniProtKB:Q04912] synonym: "PTK8" EXACT [UniProtKB:Q04912] synonym: "RON" EXACT [UniProtKB:Q04912] xref: EMBL:X70040 xref: HGNC:HGNC:7381 xref: UniGene:Hs.517973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055739 ! RON_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019768 name: ROPN1_human def: "Ropporin-1A gene" [UniProtKB:Q9HAT0] synonym: "ROPN1A" EXACT [UniProtKB:Q9HAT0] xref: EMBL:AF303889 xref: EMBL:AL133624 xref: EMBL:BC132744 xref: EMBL:BC132746 xref: HGNC:HGNC:17692 xref: UniGene:Hs.567516 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058767 ! ROP1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019769 name: ROPN1B_human def: "Ropporin-1B gene" [UniProtKB:Q9BZX4] xref: EMBL:AF231410 xref: EMBL:BC015413 xref: EMBL:BC141849 xref: HGNC:HGNC:31927 xref: UniGene:Hs.663128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058611 ! ROP1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019770 name: ROPN1L_human def: "Ropporin-1-like protein gene" [UniProtKB:Q96C74] synonym: "ASP" EXACT [UniProtKB:Q96C74] xref: EMBL:AF239723 xref: EMBL:BC014607 xref: HGNC:HGNC:24060 xref: UniGene:Hs.381089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058177 ! ROP1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019771 name: ROR1_human def: "Tyrosine-protein kinase transmembrane receptor ROR1 precursor gene" [UniProtKB:Q01973] synonym: "NTRKR1" EXACT [UniProtKB:Q01973] xref: EMBL:AL137859 xref: EMBL:AL161742 xref: EMBL:AL445205 xref: EMBL:M97675 xref: EMBL:U38894 xref: HGNC:HGNC:10256 xref: UniGene:Hs.654491 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055699 ! ROR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019772 name: ROR2_human def: "Tyrosine-protein kinase transmembrane receptor ROR2 precursor gene" [UniProtKB:Q01974] synonym: "NTRKR2" EXACT [UniProtKB:Q01974] xref: EMBL:AB209154 xref: EMBL:AF254747 xref: EMBL:AF254748 xref: EMBL:AF254749 xref: EMBL:AF254750 xref: EMBL:AF254751 xref: EMBL:AF254752 xref: EMBL:AF254753 xref: EMBL:AF279755 xref: EMBL:AF279756 xref: EMBL:AF279757 xref: EMBL:AF279758 xref: EMBL:AF279759 xref: EMBL:AF279760 xref: EMBL:AF279761 xref: EMBL:AF279762 xref: EMBL:AF294796 xref: EMBL:AL391219 xref: EMBL:AL583841 xref: EMBL:AL928802 xref: EMBL:M97639 xref: HGNC:HGNC:10257 xref: UniGene:Hs.644776 xref: UniGene:Hs.98255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055700 ! ROR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019773 name: RORC_human def: "Nuclear receptor ROR-gamma gene" [UniProtKB:P51449] synonym: "NR1F3" EXACT [UniProtKB:P51449] synonym: "RORG" EXACT [UniProtKB:P51449] synonym: "RZRG" EXACT [UniProtKB:P51449] xref: EMBL:AL834219 xref: EMBL:BC031554 xref: EMBL:U16997 xref: HGNC:HGNC:10260 xref: UniGene:Hs.256022 xref: UniGene:Hs.607993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055465 ! RORG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019774 name: RP1L1_human def: "Retinitis pigmentosa 1-like 1 protein gene" [UniProtKB:Q8IWN7] xref: EMBL:AC104964 xref: EMBL:AC105001 xref: EMBL:AJ491324 xref: EMBL:AK127545 xref: EMBL:AY168341 xref: EMBL:AY168342 xref: EMBL:AY168343 xref: EMBL:AY168344 xref: EMBL:AY168345 xref: EMBL:AY168346 xref: HGNC:HGNC:15946 xref: UniGene:Hs.33538 xref: UniGene:Hs.689495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053882 ! A6NKC6_HUMAN relationship: codes_for CCO:B0057362 ! RP1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019775 name: RP1_human def: "Oxygen-regulated protein 1 gene" [UniProtKB:P56715] synonym: "ORP1" EXACT [UniProtKB:P56715] xref: EMBL:AF141021 xref: EMBL:AF143222 xref: EMBL:AF143224 xref: EMBL:AF143225 xref: EMBL:AF143226 xref: EMBL:AF146592 xref: EMBL:AF152240 xref: EMBL:AF152241 xref: EMBL:AF152242 xref: HGNC:HGNC:10263 xref: UniGene:Hs.458845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055552 ! RP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019776 name: CD3EAP_human def: "DNA-directed RNA polymerase I subunit RPA34 gene" [UniProtKB:O15446] synonym: "ASE1" EXACT [UniProtKB:O15446] synonym: "CAST" EXACT [UniProtKB:O15446] synonym: "PAF49" EXACT [UniProtKB:O15446] xref: EMBL:AF017633 xref: EMBL:BC038992 xref: EMBL:BC054044 xref: EMBL:BC108889 xref: EMBL:U86751 xref: HGNC:HGNC:24219 xref: UniGene:Hs.705916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054437 ! RPA34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019777 name: POLR2F_human def: "DNA-directed RNA polymerases I, II, and III subunit RPABC2 gene" [UniProtKB:P61218] synonym: "POLRF" EXACT [UniProtKB:P61218] xref: EMBL:AF006501 xref: EMBL:AL031587 xref: EMBL:BC003582 xref: EMBL:CR456546 xref: EMBL:Z27113 xref: HGNC:HGNC:9193 xref: UniGene:Hs.436578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054167 ! B0QYL8_HUMAN relationship: codes_for CCO:B0054168 ! B0QYL9_HUMAN relationship: codes_for CCO:B0055606 ! RPAB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019778 name: POLR2K_human def: "DNA-directed RNA polymerases I, II, and III subunit RPABC4 gene" [UniProtKB:P53803] xref: EMBL:AJ252078 xref: EMBL:BC000806 xref: EMBL:BC018157 xref: EMBL:Z47727 xref: HGNC:HGNC:9198 xref: UniGene:Hs.351475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055511 ! RPAB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019779 name: POLR2L_human def: "DNA-directed RNA polymerases I, II, and III subunit RPABC5 gene" [UniProtKB:P62875] xref: EMBL:BC005903 xref: EMBL:BC018649 xref: EMBL:U37690 xref: EMBL:Z47728 xref: EMBL:Z47729 xref: HGNC:HGNC:9199 xref: UniGene:Hs.441072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055622 ! RPAB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019780 name: POLR2I_human def: "DNA-directed RNA polymerase II subunit RPB9 gene" [UniProtKB:P36954] xref: EMBL:AD001527 xref: EMBL:BC017112 xref: EMBL:BC067794 xref: EMBL:Z23102 xref: HGNC:HGNC:9196 xref: UniGene:Hs.47062 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055314 ! RPB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019781 name: POLR3K_human def: "DNA-directed RNA polymerase III subunit RPC10 gene" [UniProtKB:Q9Y2Y1] synonym: "My010" EXACT [UniProtKB:Q9Y2Y1] synonym: "RPC11" EXACT [UniProtKB:Q9Y2Y1] xref: EMBL:AE006462 xref: EMBL:AF051316 xref: EMBL:AF060223 xref: EMBL:AF126531 xref: EMBL:BC011932 xref: EMBL:DQ431198 xref: EMBL:Z69719 xref: HGNC:HGNC:14121 xref: UniGene:Hs.632223 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059323 ! RPC10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019782 name: POLR3C_human def: "DNA-directed RNA polymerase III subunit RPC3 gene" [UniProtKB:Q9BUI4] xref: EMBL:AJ238221 xref: EMBL:AJ238222 xref: EMBL:AJ238223 xref: EMBL:AJ238224 xref: EMBL:AJ238225 xref: EMBL:AJ238226 xref: EMBL:AJ238227 xref: EMBL:AJ238228 xref: EMBL:AJ238229 xref: EMBL:AJ238230 xref: EMBL:AJ238231 xref: EMBL:AJ238232 xref: EMBL:AJ238233 xref: EMBL:AJ238234 xref: EMBL:AY091463 xref: EMBL:BC002586 xref: EMBL:U93867 xref: HGNC:HGNC:30076 xref: UniGene:Hs.591457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058521 ! RPC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019783 name: POLR3G_human def: "DNA-directed RNA polymerase III subunit RPC7 gene" [UniProtKB:O15318] xref: EMBL:U93868 xref: HGNC:HGNC:30075 xref: UniGene:Hs.282387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054428 ! RPC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019784 name: RPE65_human def: "Retinal pigment epithelium-specific 65 kDa protein gene" [UniProtKB:Q16518] xref: EMBL:AF039855 xref: EMBL:AF039856 xref: EMBL:AF039857 xref: EMBL:AF039858 xref: EMBL:AF039859 xref: EMBL:AF039860 xref: EMBL:AF039861 xref: EMBL:AF039862 xref: EMBL:AF039863 xref: EMBL:AF039864 xref: EMBL:AF039865 xref: EMBL:AF039866 xref: EMBL:AF039867 xref: EMBL:AF039868 xref: EMBL:BC075035 xref: EMBL:BC075036 xref: EMBL:U18991 xref: EMBL:U20476 xref: EMBL:U20477 xref: EMBL:U20478 xref: EMBL:U20479 xref: EMBL:U20481 xref: EMBL:U20482 xref: EMBL:U20484 xref: EMBL:U20485 xref: EMBL:U20486 xref: EMBL:U20510 xref: HGNC:HGNC:10294 xref: UniGene:Hs.2133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056140 ! RPE65_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019785 name: RAPGEF2_human def: "Rap guanine nucleotide exchange factor 2 gene" [UniProtKB:Q9Y4G8] synonym: "KIAA0313" EXACT [UniProtKB:Q9Y4G8] synonym: "NRAPGEP" EXACT [UniProtKB:Q9Y4G8] synonym: "PDZGEF1" EXACT [UniProtKB:Q9Y4G8] xref: EMBL:AB002311 xref: HGNC:HGNC:16854 xref: UniGene:Hs.113912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059362 ! RPGF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019786 name: RAPGEF3_human def: "Rap guanine nucleotide exchange factor 3 gene" [UniProtKB:O95398] synonym: "CGEF1" EXACT [UniProtKB:O95398] synonym: "EPAC" EXACT [UniProtKB:O95398] synonym: "EPAC1" EXACT [UniProtKB:O95398] xref: EMBL:AF103905 xref: EMBL:BC017728 xref: EMBL:BC068477 xref: EMBL:BC092404 xref: EMBL:U78168 xref: EMBL:U78169 xref: HGNC:HGNC:16629 xref: UniGene:Hs.8578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054757 ! RPGF3_HUMAN relationship: codes_for CCO:B0056372 ! Q569L6_HUMAN relationship: codes_for CCO:B0056861 ! Q6NUQ6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019787 name: RAPGEF4_human def: "Rap guanine nucleotide exchange factor 4 gene" [UniProtKB:Q8WZA2] synonym: "CGEF2" EXACT [UniProtKB:Q8WZA2] synonym: "EPAC2" EXACT [UniProtKB:Q8WZA2] xref: EMBL:AB027471 xref: EMBL:BC024004 xref: EMBL:BC040183 xref: EMBL:U78516 xref: HGNC:HGNC:16626 xref: UniGene:Hs.470646 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058055 ! RPGF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019788 name: RAPGEF5_human def: "Rap guanine nucleotide exchange factor 5 gene" [UniProtKB:Q92565] synonym: "GFR" EXACT [UniProtKB:Q92565] synonym: "KIAA0277" EXACT [UniProtKB:Q92565] synonym: "MRGEF" EXACT [UniProtKB:Q92565] xref: EMBL:AC005079 xref: EMBL:BC039203 xref: EMBL:CH236948 xref: EMBL:D87467 xref: HGNC:HGNC:16862 xref: UniGene:Hs.642736 xref: UniGene:Hs.706280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053993 ! A8MQ07_HUMAN relationship: codes_for CCO:B0058064 ! RPGF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019789 name: RAPGEF6_human def: "Rap guanine nucleotide exchange factor 6 gene" [UniProtKB:Q8TEU7] synonym: "PDZGEF2" EXACT [UniProtKB:Q8TEU7] xref: EMBL:AF394782 xref: EMBL:AF478468 xref: EMBL:AF478469 xref: EMBL:AF478567 xref: EMBL:BC133703 xref: HGNC:HGNC:20655 xref: UniGene:Hs.483329 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053747 ! A3KN82_HUMAN relationship: codes_for CCO:B0057956 ! RPGF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019790 name: RAP1GAP_human def: "Rap1 GTPase-activating protein 1 gene" [UniProtKB:P47736] synonym: "KIAA0474" EXACT [UniProtKB:P47736] synonym: "RAP1GA1" EXACT [UniProtKB:P47736] xref: EMBL:AB007943 xref: EMBL:AL359815 xref: EMBL:BC035030 xref: EMBL:CH471134 xref: EMBL:M64788 xref: HGNC:HGNC:9858 xref: UniGene:Hs.148178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053988 ! A8MPS8_HUMAN relationship: codes_for CCO:B0055384 ! RPGP1_HUMAN relationship: codes_for CCO:B0056306 ! Q49AP2_HUMAN relationship: codes_for CCO:B0056570 ! Q5T3S6_HUMAN relationship: codes_for CCO:B0056571 ! Q5T3S7_HUMAN relationship: codes_for CCO:B0056572 ! Q5T3S9_HUMAN relationship: codes_for CCO:B0056573 ! Q5T3T0_HUMAN relationship: codes_for CCO:B0056574 ! Q5T3T1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019791 name: GARNL4_human def: "Rap1 GTPase-activating protein 2 gene" [UniProtKB:Q684P5] synonym: "KIAA1039" EXACT [UniProtKB:Q684P5] synonym: "RAP1GA2" EXACT [UniProtKB:Q684P5] xref: EMBL:AB028962 xref: EMBL:AJ628446 xref: EMBL:AJ628447 xref: EMBL:AK124640 xref: EMBL:CR627427 xref: HGNC:HGNC:29176 xref: UniGene:Hs.499659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056697 ! RPGP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019792 name: RRAGA_human def: "Ras-related GTP-binding protein A gene" [UniProtKB:Q7L523] xref: EMBL:AL356000 xref: EMBL:BC006433 xref: EMBL:BC009990 xref: EMBL:U41654 xref: EMBL:X90529 xref: HGNC:HGNC:16963 xref: UniGene:Hs.432330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057119 ! RRAGA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019793 name: RRAGB_human def: "Ras-related GTP-binding protein B gene" [UniProtKB:Q5VZM2] xref: EMBL:AL139277 xref: EMBL:AL159987 xref: EMBL:AL831926 xref: EMBL:BC034726 xref: EMBL:X90530 xref: HGNC:HGNC:19901 xref: UniGene:Hs.50282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056676 ! RRAGB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019794 name: RRAGC_human def: "Ras-related GTP-binding protein C gene" [UniProtKB:Q9HB90] xref: EMBL:AF272035 xref: EMBL:AF323609 xref: EMBL:AK023373 xref: EMBL:AL139260 xref: EMBL:BC016668 xref: HGNC:HGNC:19902 xref: UniGene:Hs.532461 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058781 ! RRAGC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019795 name: RREB1_human def: "RAS-responsive element-binding protein 1 gene" [UniProtKB:Q92766] synonym: "FINB" EXACT [UniProtKB:Q92766] xref: EMBL:AB019254 xref: EMBL:AB019351 xref: EMBL:AB019352 xref: EMBL:AF072825 xref: EMBL:AF072826 xref: EMBL:AL139095 xref: EMBL:AL355336 xref: EMBL:AL589644 xref: EMBL:BC042910 xref: EMBL:BC131599 xref: EMBL:D49835 xref: EMBL:U26914 xref: HGNC:HGNC:10449 xref: UniGene:Hs.699276 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058091 ! RREB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019796 name: RRN3_human def: "RNA polymerase I-specific transcription initiation factor RRN3 gene" [UniProtKB:Q9NYV6] synonym: "TIFIA" EXACT [UniProtKB:Q9NYV6] xref: EMBL:AF227156 xref: EMBL:AJ272050 xref: EMBL:BC071868 xref: HGNC:HGNC:30346 xref: UniGene:Hs.460078 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058974 ! RRN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019797 name: RSC1A1_human def: "Regulatory solute carrier protein family 1 member 1 gene" [UniProtKB:Q92681] xref: EMBL:AL121992 xref: EMBL:CH471167 xref: EMBL:X82877 xref: HGNC:HGNC:10458 xref: UniGene:Hs.145049 xref: UniGene:Hs.657818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058081 ! RSCA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019798 name: RSF1_human def: "Remodeling and spacing factor 1 gene" [UniProtKB:Q96T23] synonym: "HBXAP" EXACT [UniProtKB:Q96T23] synonym: "XAP8" EXACT [UniProtKB:Q96T23] xref: EMBL:AF059317 xref: EMBL:AF227948 xref: EMBL:AF380176 xref: EMBL:AK001268 xref: EMBL:BC046124 xref: HGNC:HGNC:18118 xref: UniGene:Hs.420229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058398 ! RSF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019799 name: RASL10A_human def: "Ras-like protein family member 10A precursor gene" [UniProtKB:Q92737] synonym: "RRP22" EXACT [UniProtKB:Q92737] xref: EMBL:BC022473 xref: EMBL:BC040434 xref: EMBL:BC050739 xref: EMBL:BC058077 xref: EMBL:Y07847 xref: HGNC:HGNC:16954 xref: UniGene:Hs.73088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058085 ! RSLAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019800 name: RASL10B_human def: "Ras-like protein family member 10B precursor gene" [UniProtKB:Q96S79] xref: EMBL:AB047296 xref: EMBL:BC041133 xref: HGNC:HGNC:30295 xref: UniGene:Hs.437035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058388 ! RSLAB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019801 name: RASL11A_human def: "Ras-like protein family member 11A gene" [UniProtKB:Q6T310] xref: EMBL:AL159977 xref: EMBL:AY439004 xref: EMBL:BC132703 xref: EMBL:CH471075 xref: HGNC:HGNC:23802 xref: UniGene:Hs.192131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056944 ! RSLBA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019802 name: RASL11B_human def: "Ras-like protein family member 11B gene" [UniProtKB:Q9BPW5] xref: EMBL:AK027267 xref: EMBL:AY839725 xref: EMBL:BC001087 xref: EMBL:BC001846 xref: EMBL:BC025694 xref: EMBL:BK001672 xref: EMBL:CH471057 xref: HGNC:HGNC:23804 xref: UniGene:Hs.8035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058470 ! RSLBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019803 name: RSPO1_human def: "R-spondin-1 precursor gene" [UniProtKB:Q2MKA7] xref: EMBL:AK098225 xref: EMBL:AL513220 xref: EMBL:BC114966 xref: EMBL:DQ165084 xref: EMBL:DQ318235 xref: HGNC:HGNC:21679 xref: UniGene:Hs.135015 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031669 ! RSPO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019804 name: RSPO2_human def: "R-spondin-2 precursor gene" [UniProtKB:Q6UXX9] synonym: "UNQ9384/PRO34209" EXACT [UniProtKB:Q6UXX9] xref: EMBL:AC025508 xref: EMBL:AP003479 xref: EMBL:AY358166 xref: EMBL:BC027938 xref: EMBL:BC036554 xref: HGNC:HGNC:28583 xref: UniGene:Hs.444834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031667 ! RSPO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019805 name: RSPO3_human def: "R-spondin-3 precursor gene" [UniProtKB:Q9BXY4] synonym: "PWTSR" EXACT [UniProtKB:Q9BXY4] synonym: "THSD2" EXACT [UniProtKB:Q9BXY4] xref: EMBL:AF251057 xref: EMBL:AK027346 xref: EMBL:AL031776 xref: EMBL:AL590733 xref: EMBL:BC022367 xref: HGNC:HGNC:20866 xref: UniGene:Hs.135254 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031673 ! RSPO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019806 name: RSPO4_human def: "R-spondin-4 precursor gene" [UniProtKB:Q2I0M5] synonym: "C20orf182" EXACT [UniProtKB:Q2I0M5] xref: EMBL:AK122609 xref: EMBL:AL050325 xref: EMBL:DQ355152 xref: HGNC:HGNC:16175 xref: UniGene:Hs.444980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031672 ! RSPO4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019807 name: RSU1_human def: "Ras suppressor protein 1 gene" [UniProtKB:Q15404] synonym: "RSP1" EXACT [UniProtKB:Q15404] xref: EMBL:BC005993 xref: EMBL:BC008691 xref: EMBL:BC015644 xref: EMBL:L12535 xref: HGNC:HGNC:10464 xref: UniGene:Hs.524161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056061 ! RSU1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019808 name: DAP3_human def: "28S ribosomal protein S29, mitochondrial gene" [UniProtKB:P51398] synonym: "MRPS29" EXACT [UniProtKB:P51398] xref: EMBL:AB061210 xref: EMBL:AL162734 xref: EMBL:U18321 xref: EMBL:X83544 xref: HGNC:HGNC:2673 xref: UniGene:Hs.516746 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055464 ! RT29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019809 name: RTKN2_human def: "Rhotekin-2 gene" [UniProtKB:Q8IZC4] synonym: "PLEKHK1" EXACT [UniProtKB:Q8IZC4] xref: EMBL:AC024597 xref: EMBL:AK096671 xref: EMBL:AL607150 xref: EMBL:AY150309 xref: EMBL:BC025765 xref: EMBL:BC048002 xref: EMBL:BC141821 xref: EMBL:BC142725 xref: EMBL:CH471083 xref: EMBL:CR749217 xref: HGNC:HGNC:19364 xref: UniGene:Hs.58559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057400 ! RTKN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019810 name: RTKN_human def: "Rhotekin gene" [UniProtKB:Q9BST9] synonym: "RTKN1" EXACT [UniProtKB:Q9BST9] xref: EMBL:AF049227 xref: EMBL:AF290512 xref: EMBL:BC004558 xref: EMBL:BC017727 xref: HGNC:HGNC:10466 xref: UniGene:Hs.192854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058510 ! RTKN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019811 name: RTN1_human def: "Reticulon-1 gene" [UniProtKB:Q16799] synonym: "NSP" EXACT [UniProtKB:Q16799] xref: EMBL:BC090862 xref: EMBL:L10333 xref: EMBL:L10334 xref: EMBL:L10335 xref: HGNC:HGNC:10467 xref: UniGene:Hs.368626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056177 ! RTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019812 name: RTN2_human def: "Reticulon-2 gene" [UniProtKB:O75298] synonym: "NSPL1" EXACT [UniProtKB:O75298] xref: EMBL:AF004222 xref: EMBL:AF004223 xref: EMBL:AF004224 xref: EMBL:AF038540 xref: EMBL:BK001686 xref: EMBL:BK001687 xref: EMBL:BK001688 xref: HGNC:HGNC:10468 xref: UniGene:Hs.47517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054615 ! RTN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019813 name: SNRP70_human def: "U1 small nuclear ribonucleoprotein 70 kDa gene" [UniProtKB:P08621] synonym: "RNPU1Z" EXACT [UniProtKB:P08621] synonym: "RPU1" EXACT [UniProtKB:P08621] synonym: "U1AP1" EXACT [UniProtKB:P08621] xref: EMBL:AL117507 xref: EMBL:BC001315 xref: EMBL:M22636 xref: EMBL:M57929 xref: EMBL:M57930 xref: EMBL:M57932 xref: EMBL:M57934 xref: EMBL:M57935 xref: EMBL:M57937 xref: EMBL:M57939 xref: EMBL:X04654 xref: EMBL:X06811 xref: EMBL:X06812 xref: EMBL:X06814 xref: EMBL:X06815 xref: EMBL:X06816 xref: EMBL:X06817 xref: EMBL:X07401 xref: EMBL:X07402 xref: EMBL:X07403 xref: EMBL:X84841 xref: HGNC:HGNC:11150 xref: UniGene:Hs.467097 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054930 ! RU17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019814 name: RUNDC3A_human def: "RUN domain-containing protein 3A gene" [UniProtKB:Q59EK9] synonym: "RAP2IP" EXACT [UniProtKB:Q59EK9] synonym: "RPIP8" EXACT [UniProtKB:Q59EK9] xref: EMBL:AB209802 xref: EMBL:AF055026 xref: EMBL:AL133657 xref: EMBL:BC006194 xref: EMBL:BX537443 xref: EMBL:CH471178 xref: EMBL:CR456748 xref: EMBL:U93871 xref: HGNC:HGNC:16984 xref: UniGene:Hs.500197 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056380 ! RUN3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019815 name: RAX_human def: "Retinal homeobox protein Rx gene" [UniProtKB:Q9Y2V3] synonym: "RX" EXACT [UniProtKB:Q9Y2V3] xref: EMBL:AF115392 xref: HGNC:HGNC:18662 xref: UniGene:Hs.278957 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059319 ! RX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019816 name: RYBP_human def: "RING1 and YY1-binding protein gene" [UniProtKB:Q8N488] synonym: "DEDAF" EXACT [UniProtKB:Q8N488] synonym: "YEAF1" EXACT [UniProtKB:Q8N488] xref: EMBL:AB029551 xref: EMBL:AF179286 xref: EMBL:AF227959 xref: EMBL:AY228125 xref: EMBL:BC014959 xref: EMBL:BC036459 xref: HGNC:HGNC:10480 xref: UniGene:Hs.694786 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057465 ! RYBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019817 name: RYK_human def: "Tyrosine-protein kinase RYK precursor gene" [UniProtKB:P34925] synonym: "JTK5A" EXACT [UniProtKB:P34925] xref: EMBL:S59184 xref: EMBL:X69970 xref: EMBL:X96588 xref: HGNC:HGNC:10481 xref: UniGene:Hs.654562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018655 ! RYK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019818 name: S100A1_human def: "Protein S100-A1 gene" [UniProtKB:P23297] synonym: "S100A" EXACT [UniProtKB:P23297] xref: EMBL:AL162258 xref: EMBL:BC014392 xref: EMBL:BT006938 xref: EMBL:X58079 xref: HGNC:HGNC:10486 xref: UniGene:Hs.515715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055155 ! S10A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019819 name: S100A10_human def: "Protein S100-A10 gene" [UniProtKB:P60903] synonym: "ANX2LG" EXACT [UniProtKB:P60903] synonym: "CAL1L" EXACT [UniProtKB:P60903] synonym: "CLP11" EXACT [UniProtKB:P60903] xref: EMBL:AL450992 xref: EMBL:BC015973 xref: EMBL:BC105786 xref: EMBL:M38591 xref: EMBL:M77483 xref: EMBL:M81457 xref: HGNC:HGNC:10487 xref: UniGene:Hs.143873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055600 ! S10AA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019820 name: SEC14L2_human def: "SEC14-like protein 2 gene" [UniProtKB:O76054] synonym: "C22orf6" EXACT [UniProtKB:O76054] synonym: "KIAA1186" EXACT [UniProtKB:O76054] synonym: "KIAA1658" EXACT [UniProtKB:O76054] xref: EMBL:AB033012 xref: EMBL:AC004832 xref: EMBL:AL096881 xref: EMBL:CR456571 xref: HGNC:HGNC:10699 xref: UniGene:Hs.335614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054690 ! S14L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019821 name: SLC20A1_human def: "Sodium-dependent phosphate transporter 1 gene" [UniProtKB:Q8WUM9] synonym: "GLVR1" EXACT [UniProtKB:Q8WUM9] synonym: "PIT1" EXACT [UniProtKB:Q8WUM9] xref: EMBL:AC079922 xref: EMBL:AF102059 xref: EMBL:AF102060 xref: EMBL:AF102061 xref: EMBL:AF102062 xref: EMBL:AF102063 xref: EMBL:BC019944 xref: EMBL:BC075818 xref: EMBL:L20859 xref: HGNC:HGNC:10946 xref: UniGene:Hs.187946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057982 ! S20A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019822 name: SLC29A2_human def: "Equilibrative nucleoside transporter 2 gene" [UniProtKB:Q14542] synonym: "DER12" EXACT [UniProtKB:Q14542] synonym: "ENT2" EXACT [UniProtKB:Q14542] synonym: "HNP36" EXACT [UniProtKB:Q14542] xref: EMBL:AF029358 xref: EMBL:AF034102 xref: EMBL:BC093634 xref: EMBL:X86681 xref: HGNC:HGNC:11004 xref: UniGene:Hs.569017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055990 ! S29A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019823 name: SLC2A4RG_human def: "SLC2A4 regulator gene" [UniProtKB:Q9NR83] synonym: "HDBP1" EXACT [UniProtKB:Q9NR83] xref: EMBL:AB044786 xref: EMBL:AB052777 xref: EMBL:AF249267 xref: EMBL:AL121845 xref: EMBL:BC001402 xref: EMBL:BC017446 xref: EMBL:BC028349 xref: EMBL:BC052306 xref: HGNC:HGNC:15930 xref: UniGene:Hs.435126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058890 ! S2A4R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019824 name: SAP30BP_human def: "SAP30-binding protein gene" [UniProtKB:Q9UHR5] synonym: "HCNGP" EXACT [UniProtKB:Q9UHR5] synonym: "HTRG" EXACT [UniProtKB:Q9UHR5] synonym: "HTRP" EXACT [UniProtKB:Q9UHR5] xref: EMBL:AF087869 xref: EMBL:AF119664 xref: EMBL:AF450482 xref: EMBL:AK095265 xref: EMBL:AY082382 xref: EMBL:BC007592 xref: EMBL:BC013409 xref: EMBL:BC030233 xref: EMBL:BC063793 xref: HGNC:HGNC:30785 xref: UniGene:Hs.655088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059148 ! S30BP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019825 name: SLC35B2_human def: "Adenosine 3'-phospho 5'-phosphosulfate transporter 1 gene" [UniProtKB:Q8TB61] synonym: "PAPST1" EXACT [UniProtKB:Q8TB61] synonym: "PSEC0149" EXACT [UniProtKB:Q8TB61] xref: EMBL:AB097021 xref: EMBL:AB097039 xref: EMBL:AB106538 xref: EMBL:AK075456 xref: EMBL:AK223028 xref: EMBL:AL139392 xref: EMBL:AY491520 xref: EMBL:BC016839 xref: EMBL:BC024288 xref: HGNC:HGNC:16872 xref: UniGene:Hs.182885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057898 ! S35B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019826 name: SIX6OS1_human def: "Protein SIX6OS1 gene" [UniProtKB:Q8N1H7] synonym: "C14orf39" EXACT [UniProtKB:Q8N1H7] xref: EMBL:AK098187 xref: HGNC:HGNC:19849 xref: UniGene:Hs.335754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057428 ! S6OS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019827 name: SAA1_human def: "Serum amyloid A protein precursor gene" [UniProtKB:P02735] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054869 ! SAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019828 name: SAA2_human def: "Serum amyloid A protein precursor gene" [UniProtKB:P02735] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054869 ! SAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019829 name: SPACA3_human def: "Sperm acrosome membrane-associated protein 3 gene" [UniProtKB:Q8IXA5] synonym: "LYC3" EXACT [UniProtKB:Q8IXA5] synonym: "LYZL3" EXACT [UniProtKB:Q8IXA5] synonym: "SLLP1" EXACT [UniProtKB:Q8IXA5] synonym: "UNQ424/PRO862" EXACT [UniProtKB:Q8IXA5] xref: EMBL:AF099029 xref: EMBL:AF216311 xref: EMBL:AY358653 xref: EMBL:BC100886 xref: EMBL:BC100887 xref: HGNC:HGNC:16260 xref: UniGene:Hs.434112 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057369 ! SACA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019830 name: SAFB_human def: "Scaffold attachment factor B1 gene" [UniProtKB:Q15424] synonym: "HAP" EXACT [UniProtKB:Q15424] synonym: "HET" EXACT [UniProtKB:Q15424] synonym: "SAFB1" EXACT [UniProtKB:Q15424] xref: EMBL:AB208780 xref: EMBL:AC004611 xref: EMBL:AC011499 xref: EMBL:AC134303 xref: EMBL:L43631 xref: EMBL:U72355 xref: HGNC:HGNC:10520 xref: UniGene:Hs.23978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056062 ! SAFB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019831 name: SAFB2_human def: "Scaffold attachment factor B2 gene" [UniProtKB:Q14151] synonym: "KIAA0138" EXACT [UniProtKB:Q14151] xref: EMBL:AC004611 xref: EMBL:BC025279 xref: EMBL:D50928 xref: HGNC:HGNC:21605 xref: UniGene:Hs.655392 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055964 ! SAFB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019832 name: SALL1_human def: "Sal-like protein 1 gene" [UniProtKB:Q9NSC2] synonym: "SAL1" EXACT [UniProtKB:Q9NSC2] xref: EMBL:AF017655 xref: EMBL:AF074949 xref: EMBL:X98833 xref: EMBL:Y18264 xref: EMBL:Y18265 xref: HGNC:HGNC:10524 xref: UniGene:Hs.135787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058914 ! SALL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019833 name: SALL2_human def: "Sal-like protein 2 gene" [UniProtKB:Q9Y467] synonym: "KIAA0360" EXACT [UniProtKB:Q9Y467] synonym: "SAL2" EXACT [UniProtKB:Q9Y467] xref: EMBL:AB002358 xref: EMBL:AF465630 xref: EMBL:BC024245 xref: EMBL:BC090958 xref: EMBL:X98834 xref: HGNC:HGNC:10526 xref: UniGene:Hs.416358 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059351 ! SALL2_HUMAN relationship: codes_for CCO:B0062886 ! Q8N656_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019834 name: SALL3_human def: "Sal-like protein 3 gene" [UniProtKB:Q9BXA9] xref: EMBL:AF347021 xref: EMBL:AJ007421 xref: HGNC:HGNC:10527 xref: UniGene:Hs.669133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058547 ! SALL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019835 name: SALL4_human def: "Sal-like protein 4 gene" [UniProtKB:Q9UJQ4] xref: EMBL:AL034420 xref: EMBL:AY172738 xref: EMBL:BC111714 xref: HGNC:HGNC:15924 xref: UniGene:Hs.517113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059174 ! SALL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019836 name: SAP30_human def: "Histone deacetylase complex subunit SAP30 gene" [UniProtKB:O75446] xref: EMBL:AF055993 xref: EMBL:BC016757 xref: HGNC:HGNC:10532 xref: UniGene:Hs.591715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054637 ! SAP30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019837 name: SAR1A_human def: "GTP-binding protein SAR1a gene" [UniProtKB:Q9NR31] synonym: "SAR1" EXACT [UniProtKB:Q9NR31] synonym: "SARA" EXACT [UniProtKB:Q9NR31] synonym: "SARA1" EXACT [UniProtKB:Q9NR31] xref: EMBL:AF261717 xref: EMBL:AL136724 xref: EMBL:AL731540 xref: EMBL:AY008268 xref: EMBL:BC003658 xref: HGNC:HGNC:10534 xref: UniGene:Hs.499960 xref: UniGene:Hs.594910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058885 ! SAR1A_HUMAN relationship: codes_for CCO:B0063333 ! Q5SQU0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019838 name: SAR1B_human def: "GTP-binding protein SAR1b gene" [UniProtKB:Q9Y6B6] synonym: "SARA2" EXACT [UniProtKB:Q9Y6B6] synonym: "SARB" EXACT [UniProtKB:Q9Y6B6] xref: EMBL:AF087850 xref: EMBL:AF092130 xref: EMBL:BC002847 xref: EMBL:BC093034 xref: HGNC:HGNC:10535 xref: UniGene:Hs.432984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059403 ! SAR1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019839 name: SARM1_human def: "Sterile alpha and TIR motif-containing protein 1 gene" [UniProtKB:Q6SZW1] synonym: "KIAA0524" EXACT [UniProtKB:Q6SZW1] synonym: "SARM" EXACT [UniProtKB:Q6SZW1] xref: EMBL:AB011096 xref: EMBL:AJ290445 xref: EMBL:AY444166 xref: EMBL:BC122860 xref: HGNC:HGNC:17074 xref: UniGene:Hs.532781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055748 ! Q05B42_HUMAN relationship: codes_for CCO:B0056942 ! SARM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019840 name: SATB2_human def: "DNA-binding protein SATB2 gene" [UniProtKB:Q9UPW6] synonym: "KIAA1034" EXACT [UniProtKB:Q9UPW6] xref: EMBL:AB028957 xref: EMBL:BC098136 xref: EMBL:BC099723 xref: EMBL:BC103492 xref: EMBL:BC103500 xref: HGNC:HGNC:21637 xref: UniGene:Hs.516617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056281 ! Q3ZB87_HUMAN relationship: codes_for CCO:B0059270 ! SATB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019841 name: SAV1_human def: "Protein salvador homolog 1 gene" [UniProtKB:Q9H4B6] synonym: "WW45" EXACT [UniProtKB:Q9H4B6] xref: EMBL:AJ292969 xref: EMBL:AK021500 xref: EMBL:AK023071 xref: EMBL:BC020537 xref: EMBL:CR457297 xref: HGNC:HGNC:17795 xref: UniGene:Hs.642842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058715 ! SAV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019842 name: SBNO2_human def: "Protein strawberry notch homolog 2 gene" [UniProtKB:Q9Y2G9] synonym: "KIAA0963" EXACT [UniProtKB:Q9Y2G9] xref: EMBL:AB023180 xref: EMBL:AC005390 xref: EMBL:AK074102 xref: EMBL:AK292407 xref: EMBL:BC106021 xref: HGNC:HGNC:29158 xref: UniGene:Hs.408708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059305 ! SBNO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019843 name: SLC6A3_human def: "Sodium-dependent dopamine transporter gene" [UniProtKB:Q01959] synonym: "DAT1" EXACT [UniProtKB:Q01959] xref: EMBL:AF119117 xref: EMBL:AF306558 xref: EMBL:AF306559 xref: EMBL:AF306560 xref: EMBL:AF306561 xref: EMBL:AF306562 xref: EMBL:AF306563 xref: EMBL:AF306564 xref: EMBL:AF321320 xref: EMBL:AF321321 xref: EMBL:AY623110 xref: EMBL:D88570 xref: EMBL:L24178 xref: EMBL:M95167 xref: EMBL:M96670 xref: EMBL:S44626 xref: EMBL:S46955 xref: HGNC:HGNC:11049 xref: UniGene:Hs.406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055697 ! SC6A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019844 name: SCAP_human def: "Sterol regulatory element-binding protein cleavage-activating protein gene" [UniProtKB:Q12770] synonym: "KIAA0199" EXACT [UniProtKB:Q12770] synonym: "PSEC0227" EXACT [UniProtKB:Q12770] xref: EMBL:AK027402 xref: EMBL:AK075528 xref: EMBL:BC020987 xref: EMBL:D83782 xref: HGNC:HGNC:30634 xref: UniGene:Hs.531789 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055838 ! SCAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019845 name: KITLG_human def: "Kit ligand precursor gene" [UniProtKB:P21583] synonym: "MGF" EXACT [UniProtKB:P21583] synonym: "SCF" EXACT [UniProtKB:P21583] xref: EMBL:AF119835 xref: EMBL:AF400436 xref: EMBL:AF400437 xref: EMBL:AK290319 xref: EMBL:AK293002 xref: EMBL:BC069733 xref: EMBL:BC069783 xref: EMBL:BC069797 xref: EMBL:BC074725 xref: EMBL:BC126166 xref: EMBL:CH471054 xref: EMBL:CR749222 xref: EMBL:M59964 xref: EMBL:S42571 xref: HGNC:HGNC:6343 xref: UniGene:Hs.1048 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055135 ! SCF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019846 name: SCG2_human def: "Secretogranin-2 precursor gene" [UniProtKB:P13521] synonym: "CHGC" EXACT [UniProtKB:P13521] xref: EMBL:AC012512 xref: EMBL:BC022509 xref: EMBL:M25756 xref: HGNC:HGNC:10575 xref: UniGene:Hs.516726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055014 ! SCG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019847 name: SCMH1_human def: "Polycomb protein SCMH1 gene" [UniProtKB:Q96GD3] xref: EMBL:AF149045 xref: EMBL:AF149046 xref: EMBL:AL110502 xref: EMBL:AL391730 xref: EMBL:AL606484 xref: EMBL:BC009752 xref: EMBL:BC021252 xref: EMBL:BX640721 xref: EMBL:CR457161 xref: HGNC:HGNC:19003 xref: UniGene:Hs.571874 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058215 ! SCMH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019848 name: SCML1_human def: "Sex comb on midleg-like protein 1 gene" [UniProtKB:Q9UN30] xref: EMBL:AF160728 xref: EMBL:BC105028 xref: EMBL:Z93242 xref: HGNC:HGNC:10580 xref: UniGene:Hs.109655 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059246 ! SCML1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019849 name: SCML2_human def: "Sex comb on midleg-like protein 2 gene" [UniProtKB:Q9UQR0] xref: EMBL:AL031007 xref: EMBL:AL096763 xref: EMBL:AL833937 xref: EMBL:BC040497 xref: EMBL:BC051913 xref: EMBL:BC064617 xref: EMBL:CH471074 xref: EMBL:Y18004 xref: EMBL:Z93023 xref: HGNC:HGNC:10581 xref: UniGene:Hs.495774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056498 ! Q5JXE6_HUMAN relationship: codes_for CCO:B0059284 ! SCML2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019850 name: SCML4_human def: "Sex comb on midleg-like protein 4 gene" [UniProtKB:Q8N228] xref: EMBL:AK093571 xref: EMBL:AL096816 xref: EMBL:AL512592 xref: EMBL:BC033286 xref: EMBL:CH471051 xref: HGNC:HGNC:21397 xref: UniGene:Hs.486109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057436 ! SCML4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019851 name: SCRT1_human def: "Transcriptional repressor scratch 1 gene" [UniProtKB:Q9BWW7] xref: EMBL:AY014996 xref: EMBL:BC014675 xref: EMBL:CH471162 xref: HGNC:HGNC:15950 xref: UniGene:Hs.31746 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058542 ! SCRT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019852 name: SCRT2_human def: "Transcriptional repressor scratch 2 gene" [UniProtKB:Q9NQ03] synonym: "FP7030" EXACT [UniProtKB:Q9NQ03] xref: EMBL:AL121758 xref: EMBL:AY129025 xref: HGNC:HGNC:15952 xref: UniGene:Hs.355284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058857 ! SCRT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019853 name: SECTM1_human def: "Secreted and transmembrane protein 1 precursor gene" [UniProtKB:Q8WVN6] xref: EMBL:BC017716 xref: EMBL:U77643 xref: HGNC:HGNC:10707 xref: UniGene:Hs.558009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057996 ! SCTM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019854 name: SCTR_human def: "Secretin receptor precursor gene" [UniProtKB:P47872] xref: EMBL:AB065660 xref: EMBL:AY462218 xref: EMBL:U13989 xref: EMBL:U20178 xref: EMBL:U28281 xref: HGNC:HGNC:10608 xref: UniGene:Hs.42091 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015136 ! SCTR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019855 name: SCXA_human def: "Basic helix-loop-helix transcription factor scleraxis gene" [UniProtKB:Q7RTU7] synonym: "SCX" EXACT [UniProtKB:Q7RTU7] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057137 ! SCX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019856 name: SCXB_human def: "Basic helix-loop-helix transcription factor scleraxis gene" [UniProtKB:Q7RTU7] synonym: "SCX" EXACT [UniProtKB:Q7RTU7] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057137 ! SCX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019857 name: SDCBP_human def: "Syntenin-1 gene" [UniProtKB:O00560] synonym: "MDA9" EXACT [UniProtKB:O00560] synonym: "SYCL" EXACT [UniProtKB:O00560] xref: EMBL:AF000652 xref: EMBL:AF006636 xref: EMBL:BC113674 xref: EMBL:BC113676 xref: EMBL:U83463 xref: HGNC:HGNC:10662 xref: UniGene:Hs.200804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054332 ! SDCB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019858 name: SDCBP2_human def: "Syntenin-2 gene" [UniProtKB:Q9H190] synonym: "SITAC18" EXACT [UniProtKB:Q9H190] xref: EMBL:AF131809 xref: EMBL:AF159228 xref: EMBL:AJ292244 xref: EMBL:AJ292245 xref: EMBL:AL136531 xref: EMBL:BC002727 xref: HGNC:HGNC:15756 xref: UniGene:Hs.657015 xref: UniGene:Hs.693882 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058662 ! SDCB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019859 name: CXCL12_human def: "Stromal cell-derived factor 1 precursor gene" [UniProtKB:P48061] synonym: "SDF1" EXACT [UniProtKB:P48061] synonym: "SDF1A" EXACT [UniProtKB:P48061] synonym: "SDF1B" EXACT [UniProtKB:P48061] xref: EMBL:AL137026 xref: EMBL:AY802782 xref: EMBL:BC039893 xref: EMBL:L36033 xref: EMBL:L36034 xref: EMBL:U16752 xref: EMBL:U19495 xref: HGNC:HGNC:10672 xref: UniGene:Hs.522891 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055399 ! SDF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019860 name: SEL1L_human def: "Protein sel-1 homolog 1 precursor gene" [UniProtKB:Q9UBV2] synonym: "TSA305" EXACT [UniProtKB:Q9UBV2] synonym: "UNQ128/PRO1063" EXACT [UniProtKB:Q9UBV2] xref: EMBL:AB020335 xref: EMBL:AB024763 xref: EMBL:AF052059 xref: EMBL:AF157516 xref: EMBL:AF198631 xref: EMBL:AF198632 xref: EMBL:AF198633 xref: EMBL:AF198634 xref: EMBL:AF198635 xref: EMBL:AF198636 xref: EMBL:AF198637 xref: EMBL:AF198638 xref: EMBL:AF198639 xref: EMBL:AF198640 xref: EMBL:AF198641 xref: EMBL:AF198642 xref: EMBL:AF198643 xref: EMBL:AF198644 xref: EMBL:AF198645 xref: EMBL:AF198646 xref: EMBL:AF198647 xref: EMBL:AY358651 xref: HGNC:HGNC:10717 xref: UniGene:Hs.181300 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059086 ! SE1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019861 name: SEBOX_human def: "Homeobox protein SEBOX gene" [UniProtKB:Q9HB31] synonym: "OG9X" EXACT [UniProtKB:Q9HB31] xref: EMBL:AF284337 xref: EMBL:CH471159 xref: HGNC:HGNC:32942 xref: UniGene:Hs.2257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058774 ! SEBOX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019862 name: BNIP1_human def: "Vesicle transport protein SEC20 gene" [UniProtKB:Q12981] synonym: "NIP1" EXACT [UniProtKB:Q12981] synonym: "SEC20L" EXACT [UniProtKB:Q12981] synonym: "TRG8" EXACT [UniProtKB:Q12981] xref: EMBL:AF083956 xref: EMBL:AF083957 xref: EMBL:AF083958 xref: EMBL:AY216799 xref: EMBL:AY246554 xref: EMBL:BC010959 xref: EMBL:U15172 xref: HGNC:HGNC:1082 xref: UniGene:Hs.145726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055862 ! SEC20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019863 name: EEFSEC_human def: "Selenocysteine-specific elongation factor gene" [UniProtKB:P57772] synonym: "SELB" EXACT [UniProtKB:P57772] xref: EMBL:AF268872 xref: EMBL:AL449210 xref: EMBL:AL449214 xref: EMBL:AL449217 xref: HGNC:HGNC:24614 xref: UniGene:Hs.477498 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055561 ! SELB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019864 name: SELS_human def: "Selenoprotein S gene" [UniProtKB:Q9BQE4] synonym: "AD-015" EXACT [UniProtKB:Q9BQE4] synonym: "SBBI8" EXACT [UniProtKB:Q9BQE4] synonym: "VIMP" EXACT [UniProtKB:Q9BQE4] xref: EMBL:AF157317 xref: EMBL:AF328864 xref: EMBL:AY324824 xref: EMBL:BC005840 xref: EMBL:BC107774 xref: UniGene:Hs.32148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058480 ! SELS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019865 name: SELT_human def: "Selenoprotein T precursor gene" [UniProtKB:P62341] synonym: "UNQ150/PRO176" EXACT [UniProtKB:P62341] xref: EMBL:AF131856 xref: EMBL:AF195141 xref: EMBL:AY358095 xref: EMBL:AY358096 xref: EMBL:BC006012 xref: EMBL:BC008411 xref: EMBL:BC009556 xref: EMBL:BC009611 xref: EMBL:BC026350 xref: EMBL:BC036738 xref: EMBL:BC071699 xref: UniGene:Hs.369052 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055617 ! SELT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019866 name: SEMA3C_human def: "Semaphorin-3C precursor gene" [UniProtKB:Q99985] synonym: "SEMAE" EXACT [UniProtKB:Q99985] xref: EMBL:AB000220 xref: EMBL:BC030690 xref: HGNC:HGNC:10725 xref: UniGene:Hs.269109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058465 ! SEM3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019867 name: SEMA4D_human def: "Semaphorin-4D precursor gene" [UniProtKB:Q92854] synonym: "CD100" EXACT [UniProtKB:Q92854] synonym: "SEMAJ" EXACT [UniProtKB:Q92854] xref: EMBL:BC054500 xref: EMBL:U60800 xref: HGNC:HGNC:10732 xref: UniGene:Hs.655281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058107 ! SEM4D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019868 name: SEMA6A_human def: "Semaphorin-6A precursor gene" [UniProtKB:Q9H2E6] synonym: "KIAA1368" EXACT [UniProtKB:Q9H2E6] synonym: "SEMAQ" EXACT [UniProtKB:Q9H2E6] xref: EMBL:AB037789 xref: EMBL:AF279656 xref: HGNC:HGNC:10738 xref: UniGene:Hs.156967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058685 ! SEM6A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019869 name: SERINC3_human def: "Serine incorporator 3 gene" [UniProtKB:Q13530] synonym: "DIFF33" EXACT [UniProtKB:Q13530] synonym: "SBBI99" EXACT [UniProtKB:Q13530] synonym: "TDE1" EXACT [UniProtKB:Q13530] xref: EMBL:AF112227 xref: EMBL:AF153979 xref: EMBL:BC006088 xref: EMBL:U49188 xref: EMBL:Z97053 xref: HGNC:HGNC:11699 xref: UniGene:Hs.272168 xref: UniGene:Hs.696043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055925 ! SERC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019870 name: SETD7_human def: "Histone-lysine N-methyltransferase SETD7 gene" [UniProtKB:Q8WTS6] synonym: "KIAA1717" EXACT [UniProtKB:Q8WTS6] synonym: "KMT7" EXACT [UniProtKB:Q8WTS6] synonym: "SET7" EXACT [UniProtKB:Q8WTS6] synonym: "SET9" EXACT [UniProtKB:Q8WTS6] xref: EMBL:AB051504 xref: EMBL:AC112236 xref: EMBL:AC114743 xref: EMBL:AF462150 xref: EMBL:BC121055 xref: EMBL:BC121056 xref: HGNC:HGNC:30412 xref: UniGene:Hs.480792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057972 ! SETD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019871 name: SF1_human def: "Splicing factor 1 gene" [UniProtKB:Q15637] synonym: "ZFM1" EXACT [UniProtKB:Q15637] synonym: "ZNF162" EXACT [UniProtKB:Q15637] xref: EMBL:AJ000051 xref: EMBL:AJ000052 xref: EMBL:BC000773 xref: EMBL:BC008080 xref: EMBL:BC008724 xref: EMBL:BC011657 xref: EMBL:BC020217 xref: EMBL:BC038446 xref: EMBL:D26120 xref: EMBL:L49345 xref: EMBL:L49380 xref: EMBL:Y08765 xref: EMBL:Y08766 xref: HGNC:HGNC:12950 xref: UniGene:Hs.502829 xref: UniGene:Hs.658141 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056089 ! SF01_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019872 name: SFRS17A_human def: "Splicing factor, arginine/serine-rich 17A gene" [UniProtKB:Q02040] synonym: "CXYorf3" EXACT [UniProtKB:Q02040] synonym: "DXYS155E" EXACT [UniProtKB:Q02040] synonym: "XE7" EXACT [UniProtKB:Q02040] xref: EMBL:AL683807 xref: EMBL:BC028151 xref: EMBL:BC110496 xref: EMBL:BC110497 xref: EMBL:L03426 xref: EMBL:M99578 xref: HGNC:HGNC:18783 xref: UniGene:Hs.522572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055701 ! SF17A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019873 name: SFRP1_human def: "Secreted frizzled-related protein 1 precursor gene" [UniProtKB:Q8N474] synonym: "FRP" EXACT [UniProtKB:Q8N474] synonym: "FRP1" EXACT [UniProtKB:Q8N474] synonym: "SARP2" EXACT [UniProtKB:Q8N474] xref: EMBL:AF001900 xref: EMBL:AF017987 xref: EMBL:AF056087 xref: EMBL:BC036503 xref: HGNC:HGNC:10776 xref: UniGene:Hs.695991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057464 ! SFRP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019874 name: SFRP2_human def: "Secreted frizzled-related protein 2 precursor gene" [UniProtKB:Q96HF1] synonym: "FKSG12" EXACT [UniProtKB:Q96HF1] synonym: "FRP2" EXACT [UniProtKB:Q96HF1] synonym: "SARP1" EXACT [UniProtKB:Q96HF1] synonym: "UNQ361/PRO697" EXACT [UniProtKB:Q96HF1] xref: EMBL:AF017986 xref: EMBL:AF311912 xref: EMBL:AY359001 xref: EMBL:BC008666 xref: HGNC:HGNC:10777 xref: UniGene:Hs.481022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058221 ! SFRP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019875 name: FRZB_human def: "Secreted frizzled-related protein 3 precursor gene" [UniProtKB:Q92765] synonym: "FIZ" EXACT [UniProtKB:Q92765] synonym: "FRE" EXACT [UniProtKB:Q92765] synonym: "FRP" EXACT [UniProtKB:Q92765] synonym: "FRZB1" EXACT [UniProtKB:Q92765] synonym: "SFRP3" EXACT [UniProtKB:Q92765] xref: EMBL:BC027855 xref: EMBL:BT019883 xref: EMBL:U24163 xref: EMBL:U68057 xref: EMBL:U91903 xref: HGNC:HGNC:3959 xref: UniGene:Hs.128453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058090 ! SFRP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019876 name: SFRP4_human def: "Secreted frizzled-related protein 4 precursor gene" [UniProtKB:Q6FHJ7] synonym: "FRPHE" EXACT [UniProtKB:Q6FHJ7] xref: EMBL:AF026692 xref: EMBL:BC032828 xref: EMBL:BC058911 xref: EMBL:BT019679 xref: EMBL:CR541731 xref: EMBL:CR541755 xref: HGNC:HGNC:10778 xref: UniGene:Hs.658169 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056733 ! SFRP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019877 name: SFRP5_human def: "Secreted frizzled-related protein 5 precursor gene" [UniProtKB:Q5T4F7] synonym: "FRP1B" EXACT [UniProtKB:Q5T4F7] synonym: "SARP3" EXACT [UniProtKB:Q5T4F7] xref: EMBL:AF017988 xref: EMBL:AF117758 xref: EMBL:AL358938 xref: EMBL:BC050435 xref: EMBL:CR596705 xref: HGNC:HGNC:10779 xref: UniGene:Hs.279565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056575 ! SFRP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019878 name: SFRS8_human def: "Splicing factor, arginine/serine-rich 8 gene" [UniProtKB:Q12872] synonym: "SWAP" EXACT [UniProtKB:Q12872] xref: EMBL:BC008707 xref: EMBL:BC015953 xref: EMBL:U08377 xref: HGNC:HGNC:10790 xref: UniGene:Hs.308171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055853 ! SFRS8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019879 name: SFTPD_human def: "Pulmonary surfactant-associated protein D precursor gene" [UniProtKB:P35247] synonym: "PSPD" EXACT [UniProtKB:P35247] synonym: "SFTP4" EXACT [UniProtKB:P35247] xref: EMBL:AL512662 xref: EMBL:AY216721 xref: EMBL:BC022318 xref: EMBL:CR541948 xref: EMBL:L05483 xref: EMBL:L05484 xref: EMBL:L05485 xref: EMBL:X65018 xref: HGNC:HGNC:10803 xref: UniGene:Hs.253495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055282 ! SFTPD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019880 name: SCGB3A1_human def: "Secretoglobin family 3A member 1 precursor gene" [UniProtKB:Q96QR1] synonym: "HIN1" EXACT [UniProtKB:Q96QR1] synonym: "PNSP2" EXACT [UniProtKB:Q96QR1] synonym: "UGRP2" EXACT [UniProtKB:Q96QR1] synonym: "UNQ629/PRO1245" EXACT [UniProtKB:Q96QR1] xref: EMBL:AF313458 xref: EMBL:AF436839 xref: EMBL:AY040564 xref: EMBL:AY359064 xref: EMBL:BC029176 xref: EMBL:BC072673 xref: HGNC:HGNC:18384 xref: UniGene:Hs.62492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058356 ! SG3A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019881 name: SGEF_human def: "SH3 domain-containing guanine exchange factor gene" [UniProtKB:Q96DR7] synonym: "HMFN1864" EXACT [UniProtKB:Q96DR7] xref: EMBL:AB073386 xref: EMBL:AF415175 xref: EMBL:AF415176 xref: EMBL:AK022655 xref: EMBL:AK022884 xref: EMBL:AL117429 xref: EMBL:AY552599 xref: EMBL:BC016628 xref: EMBL:BC078655 xref: UniGene:Hs.570682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058195 ! SGEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019882 name: SGSM1_human def: "Small G protein signaling modulator 1 gene" [UniProtKB:Q2NKQ1] synonym: "KIAA1941" EXACT [UniProtKB:Q2NKQ1] synonym: "RUTBC2" EXACT [UniProtKB:Q2NKQ1] xref: EMBL:AB075821 xref: EMBL:AB275761 xref: EMBL:AL049759 xref: EMBL:AP000359 xref: EMBL:BC036915 xref: EMBL:BC111698 xref: HGNC:HGNC:29410 xref: UniGene:Hs.474397 xref: UniGene:Hs.620906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054046 ! A8MUT4_HUMAN relationship: codes_for CCO:B0056218 ! SGSM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019883 name: SGSM2_human def: "Small G protein signaling modulator 2 gene" [UniProtKB:O43147] synonym: "KIAA0397" EXACT [UniProtKB:O43147] synonym: "RUTBC1" EXACT [UniProtKB:O43147] xref: EMBL:AB007857 xref: EMBL:AB275762 xref: EMBL:AK125203 xref: EMBL:BC039204 xref: EMBL:BC040590 xref: HGNC:HGNC:29026 xref: UniGene:Hs.513861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054449 ! SGSM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019884 name: ECD_human def: "Protein SGT1 gene" [UniProtKB:O95905] synonym: "SGT1" EXACT [UniProtKB:O95905] xref: EMBL:BC000721 xref: EMBL:D88208 xref: HGNC:HGNC:17029 xref: UniGene:Hs.631822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054803 ! SGT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019885 name: SH2D3A_human def: "SH2 domain-containing protein 3A gene" [UniProtKB:Q9BRG2] synonym: "NSP1" EXACT [UniProtKB:Q9BRG2] synonym: "UNQ175/PRO201" EXACT [UniProtKB:Q9BRG2] xref: EMBL:AF124249 xref: EMBL:AY358406 xref: EMBL:BC006281 xref: HGNC:HGNC:16885 xref: UniGene:Hs.439645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058491 ! SH23A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019886 name: SH2B1_human def: "SH2B adapter protein 1 gene" [UniProtKB:Q9NRF2] synonym: "KIAA1299" EXACT [UniProtKB:Q9NRF2] synonym: "SH2B" EXACT [UniProtKB:Q9NRF2] xref: EMBL:AB037720 xref: EMBL:AF227967 xref: EMBL:AF227968 xref: EMBL:AF227969 xref: EMBL:AK027488 xref: EMBL:AK290332 xref: EMBL:AL049924 xref: EMBL:AL713760 xref: EMBL:BC010704 xref: HGNC:HGNC:30417 xref: UniGene:Hs.15744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058899 ! SH2B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019887 name: SH2B2_human def: "SH2B adapter protein 2 gene" [UniProtKB:O14492] synonym: "APS" EXACT [UniProtKB:O14492] xref: EMBL:AB000520 xref: EMBL:AC005088 xref: HGNC:HGNC:17381 xref: UniGene:Hs.489448 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054343 ! SH2B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019888 name: SH2B3_human def: "SH2B adapter protein 3 gene" [UniProtKB:Q9UQQ2] synonym: "LNK" EXACT [UniProtKB:Q9UQQ2] xref: EMBL:AF055581 xref: EMBL:AJ012793 xref: HGNC:HGNC:29605 xref: UniGene:Hs.506784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059283 ! SH2B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019889 name: SH2D3C_human def: "SH2 domain-containing protein 3C gene" [UniProtKB:Q8N5H7] synonym: "NSP3" EXACT [UniProtKB:Q8N5H7] synonym: "UNQ272/PRO309/PRO34088" EXACT [UniProtKB:Q8N5H7] xref: EMBL:AF124251 xref: EMBL:AK056068 xref: EMBL:AL162426 xref: EMBL:AL162586 xref: EMBL:AY358089 xref: EMBL:AY358440 xref: EMBL:BC027962 xref: EMBL:BC032365 xref: EMBL:BX647905 xref: HGNC:HGNC:16884 xref: UniGene:Hs.306412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056484 ! Q5JU31_HUMAN relationship: codes_for CCO:B0057474 ! SH2D3_HUMAN relationship: codes_for CCO:B0063487 ! Q5JU30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019890 name: SHANK2_human def: "SH3 and multiple ankyrin repeat domains protein 2 gene" [UniProtKB:Q9UPX8] synonym: "CORTBP1" EXACT [UniProtKB:Q9UPX8] synonym: "KIAA1022" EXACT [UniProtKB:Q9UPX8] xref: EMBL:AB028945 xref: EMBL:AF141901 xref: EMBL:AP001271 xref: EMBL:BC093885 xref: EMBL:BC112097 xref: EMBL:DQ152234 xref: HGNC:HGNC:14295 xref: UniGene:Hs.268726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059272 ! SHAN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019891 name: SHANK3_human def: "SH3 and multiple ankyrin repeat domains protein 3 gene" [UniProtKB:Q9BYB0] synonym: "KIAA1650" EXACT [UniProtKB:Q9BYB0] synonym: "PSAP2" EXACT [UniProtKB:Q9BYB0] xref: EMBL:AB051437 xref: EMBL:AC000036 xref: EMBL:AC000050 xref: EMBL:AK074038 xref: HGNC:HGNC:14294 xref: UniGene:Hs.149035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058573 ! SHAN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019892 name: SHB_human def: "SH2 domain-containing adapter protein B gene" [UniProtKB:Q15464] xref: EMBL:AL138752 xref: EMBL:AL161448 xref: EMBL:AL583849 xref: EMBL:BC094765 xref: EMBL:X75342 xref: HGNC:HGNC:10838 xref: UniGene:Hs.521482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056065 ! SHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019893 name: SHC2_human def: "SHC-transforming protein 2 gene" [UniProtKB:P98077] synonym: "SCK" EXACT [UniProtKB:P98077] synonym: "SHCB" EXACT [UniProtKB:P98077] xref: EMBL:AB001451 xref: EMBL:AC006124 xref: EMBL:AC008988 xref: EMBL:AC138433 xref: EMBL:AL360254 xref: HGNC:HGNC:29869 xref: UniGene:Hs.30965 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055667 ! SHC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019894 name: SHC3_human def: "SHC-transforming protein 3 gene" [UniProtKB:Q92529] synonym: "NSHC" EXACT [UniProtKB:Q92529] synonym: "SHCC" EXACT [UniProtKB:Q92529] xref: EMBL:BC026314 xref: EMBL:D84361 xref: HGNC:HGNC:18181 xref: UniGene:Hs.656806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058060 ! SHC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019895 name: SHC4_human def: "SHC-transforming protein 4 gene" [UniProtKB:Q6S5L8] synonym: "UNQ6438/PRO21364" EXACT [UniProtKB:Q6S5L8] xref: EMBL:AY358250 xref: EMBL:AY464565 xref: EMBL:BC033907 xref: HGNC:HGNC:16743 xref: UniGene:Hs.642615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056938 ! SHC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019896 name: SHH_human def: "Sonic hedgehog protein precursor gene" [UniProtKB:Q15465] xref: EMBL:AC002484 xref: EMBL:AC078834 xref: EMBL:AY422195 xref: EMBL:L38518 xref: HGNC:HGNC:10848 xref: UniGene:Hs.164537 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056066 ! SHH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019897 name: INPP5D_human def: "Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 gene" [UniProtKB:Q92835] synonym: "SHIP" EXACT [UniProtKB:Q92835] synonym: "SHIP1" EXACT [UniProtKB:Q92835] xref: EMBL:BC062985 xref: EMBL:BC099920 xref: EMBL:BC113580 xref: EMBL:BC113582 xref: EMBL:U50040 xref: EMBL:U50041 xref: EMBL:U53470 xref: EMBL:U57650 xref: EMBL:U84400 xref: EMBL:X98429 xref: HGNC:HGNC:6079 xref: UniGene:Hs.262886 xref: UniGene:Hs.601911 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058100 ! SHIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019898 name: SH3GLB1_human def: "Endophilin-B1 gene" [UniProtKB:Q9Y371] synonym: "CGI-61" EXACT [UniProtKB:Q9Y371] synonym: "KIAA0491" EXACT [UniProtKB:Q9Y371] xref: EMBL:AB007960 xref: EMBL:AF151819 xref: EMBL:AF257318 xref: EMBL:AF263293 xref: EMBL:AF350371 xref: EMBL:AK001954 xref: EMBL:AL049597 xref: EMBL:BC007455 xref: HGNC:HGNC:10833 xref: UniGene:Hs.136309 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059333 ! SHLB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019899 name: SHOX2_human def: "Short stature homeobox protein 2 gene" [UniProtKB:O60902] synonym: "OG12X" EXACT [UniProtKB:O60902] synonym: "SHOT" EXACT [UniProtKB:O60902] xref: EMBL:AC112502 xref: EMBL:AF022654 xref: EMBL:AF023203 xref: EMBL:AJ002367 xref: EMBL:AJ002368 xref: EMBL:AK095338 xref: EMBL:BC008829 xref: EMBL:CH471052 xref: HGNC:HGNC:10854 xref: UniGene:Hs.55967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053896 ! A6NLG4_HUMAN relationship: codes_for CCO:B0054588 ! SHOX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019900 name: SHOX_human def: "Short stature homeobox protein gene" [UniProtKB:O15266] synonym: "PHOG" EXACT [UniProtKB:O15266] xref: EMBL:U82668 xref: EMBL:U89331 xref: EMBL:Y11535 xref: EMBL:Y11536 xref: HGNC:HGNC:10853 xref: UniGene:Hs.105932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054422 ! SHOX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019901 name: SHROOM3_human def: "Protein Shroom3 gene" [UniProtKB:Q8TF72] synonym: "KIAA1481" EXACT [UniProtKB:Q8TF72] synonym: "MSTP013" EXACT [UniProtKB:Q8TF72] synonym: "SHRML" EXACT [UniProtKB:Q8TF72] xref: EMBL:AB040914 xref: EMBL:AB055660 xref: EMBL:AF109367 xref: EMBL:AK127929 xref: EMBL:BC007291 xref: HGNC:HGNC:30422 xref: UniGene:Hs.640107 xref: UniGene:Hs.702168 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057967 ! SHRM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019902 name: SHISA5_human def: "Protein shisa-5 precursor gene" [UniProtKB:Q8N114] synonym: "PSEC0133" EXACT [UniProtKB:Q8N114] synonym: "SCOTIN" EXACT [UniProtKB:Q8N114] xref: EMBL:AB097007 xref: EMBL:AF520698 xref: EMBL:AF520702 xref: EMBL:AF520703 xref: EMBL:AK056328 xref: EMBL:AK075441 xref: EMBL:AL117413 xref: EMBL:AL832568 xref: EMBL:BC001463 xref: EMBL:CH471055 xref: HGNC:HGNC:30376 xref: UniGene:Hs.414579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057421 ! SHSA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019903 name: SIPA1L1_human def: "Signal-induced proliferation-associated 1-like protein 1 gene" [UniProtKB:O43166] synonym: "E6TP1" EXACT [UniProtKB:O43166] synonym: "KIAA0440" EXACT [UniProtKB:O43166] xref: EMBL:AB007900 xref: EMBL:AC004900 xref: EMBL:AC004974 xref: EMBL:AF090989 xref: EMBL:AF090990 xref: HGNC:HGNC:20284 xref: UniGene:Hs.654657 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054452 ! SI1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019904 name: SIPA1L3_human def: "Signal-induced proliferation-associated 1-like protein 3 gene" [UniProtKB:O60292] synonym: "KIAA0545" EXACT [UniProtKB:O60292] synonym: "SPAL3" EXACT [UniProtKB:O60292] xref: EMBL:AB011117 xref: EMBL:AY168880 xref: HGNC:HGNC:23801 xref: UniGene:Hs.655502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054542 ! SI1L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019905 name: SIGIRR_human def: "Single Ig IL-1-related receptor gene" [UniProtKB:Q6IA17] synonym: "UNQ301/PRO342" EXACT [UniProtKB:Q6IA17] xref: EMBL:AK025099 xref: EMBL:AY358342 xref: EMBL:BC003591 xref: EMBL:BC025953 xref: EMBL:BC106007 xref: EMBL:CR457338 xref: HGNC:HGNC:30575 xref: UniGene:Hs.501624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056756 ! SIGIR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019906 name: SIGLEC8_human def: "Sialic acid-binding Ig-like lectin 8 precursor gene" [UniProtKB:Q9NYZ4] synonym: "SAF2" EXACT [UniProtKB:Q9NYZ4] xref: EMBL:AF195092 xref: EMBL:AF223403 xref: EMBL:AF287892 xref: EMBL:AF310234 xref: EMBL:BC053319 xref: HGNC:HGNC:10877 xref: UniGene:Hs.447899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058988 ! SIGL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019907 name: SIGLEC9_human def: "Sialic acid-binding Ig-like lectin 9 precursor gene" [UniProtKB:Q9Y336] synonym: "UNQ668/PRO1302" EXACT [UniProtKB:Q9Y336] xref: EMBL:AB026265 xref: EMBL:AC011473 xref: EMBL:AF135027 xref: EMBL:AF227924 xref: EMBL:AF247180 xref: EMBL:AY358913 xref: HGNC:HGNC:10878 xref: UniGene:Hs.245828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059330 ! SIGL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019908 name: SIM1_human def: "Single-minded homolog 1 gene" [UniProtKB:P81133] xref: EMBL:AL121948 xref: EMBL:U70212 xref: EMBL:Z86062 xref: HGNC:HGNC:10882 xref: UniGene:Hs.520293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055654 ! SIM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019909 name: SIM2_human def: "Single-minded homolog 2 gene" [UniProtKB:Q14190] xref: EMBL:AB003185 xref: EMBL:AJ001858 xref: EMBL:AP000697 xref: EMBL:AP001726 xref: EMBL:D44444 xref: EMBL:D44445 xref: EMBL:D44446 xref: EMBL:D44447 xref: EMBL:D44448 xref: EMBL:D70838 xref: EMBL:D85922 xref: EMBL:U80456 xref: EMBL:U80457 xref: EMBL:X84790 xref: HGNC:HGNC:10883 xref: UniGene:Hs.146186 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055969 ! SIM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019910 name: SIRPB1_human def: "Signal-regulatory protein beta-1 precursor gene" [UniProtKB:O00241] xref: EMBL:AK313517 xref: EMBL:AL049634 xref: EMBL:AL138804 xref: EMBL:BC025286 xref: EMBL:BC075835 xref: EMBL:Y10376 xref: HGNC:HGNC:15928 xref: UniGene:Hs.664861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054302 ! SIRB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019911 name: SIRPG_human def: "Signal-regulatory protein gamma precursor gene" [UniProtKB:Q9P1W8] synonym: "SIRPB2" EXACT [UniProtKB:Q9P1W8] xref: EMBL:AB042624 xref: EMBL:AL109809 xref: EMBL:AL138804 xref: EMBL:AY748247 xref: EMBL:AY748248 xref: EMBL:BC020629 xref: EMBL:BC064532 xref: HGNC:HGNC:15757 xref: UniGene:Hs.590883 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059045 ! SIRPG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019912 name: SIRT1_human def: "NAD-dependent deacetylase sirtuin-1 gene" [UniProtKB:Q96EB6] synonym: "SIR2L1" EXACT [UniProtKB:Q96EB6] xref: EMBL:AF083106 xref: EMBL:AF235040 xref: EMBL:AK074805 xref: EMBL:AL133551 xref: EMBL:BC012499 xref: EMBL:DQ278604 xref: HGNC:HGNC:14929 xref: UniGene:Hs.369779 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054178 ! B0QZ35_HUMAN relationship: codes_for CCO:B0058204 ! SIRT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019913 name: SIRT3_human def: "NAD-dependent deacetylase sirtuin-3, mitochondrial precursor gene" [UniProtKB:Q9NTG7] synonym: "SIR2L3" EXACT [UniProtKB:Q9NTG7] xref: EMBL:AF083108 xref: EMBL:AL137276 xref: EMBL:BC001042 xref: HGNC:HGNC:14931 xref: UniGene:Hs.592292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058924 ! SIRT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019914 name: SIRT4_human def: "NAD-dependent deacetylase sirtuin-4 gene" [UniProtKB:Q9Y6E7] synonym: "SIR2L4" EXACT [UniProtKB:Q9Y6E7] xref: EMBL:AC003982 xref: EMBL:AF083109 xref: EMBL:BC109319 xref: EMBL:BC109320 xref: HGNC:HGNC:14932 xref: UniGene:Hs.50861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059404 ! SIRT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019915 name: SIRT5_human def: "NAD-dependent deacetylase sirtuin-5 gene" [UniProtKB:Q9NXA8] synonym: "SIR2L5" EXACT [UniProtKB:Q9NXA8] xref: EMBL:AF083110 xref: EMBL:AK000355 xref: EMBL:AL441883 xref: EMBL:AM393414 xref: EMBL:BC000126 xref: HGNC:HGNC:14933 xref: UniGene:Hs.567431 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058951 ! SIRT5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019916 name: SIRT6_human def: "Mono-ADP-ribosyltransferase sirtuin-6 gene" [UniProtKB:Q8N6T7] synonym: "SIR2L6" EXACT [UniProtKB:Q8N6T7] xref: EMBL:AC005620 xref: EMBL:AC006930 xref: EMBL:AF233396 xref: EMBL:AK074810 xref: EMBL:BC000090 xref: EMBL:BC004218 xref: EMBL:BC005026 xref: EMBL:BC028220 xref: EMBL:CR457200 xref: HGNC:HGNC:14934 xref: UniGene:Hs.423756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057492 ! SIRT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019917 name: SIRT7_human def: "NAD-dependent deacetylase sirtuin-7 gene" [UniProtKB:Q9NRC8] synonym: "SIR2L7" EXACT [UniProtKB:Q9NRC8] xref: EMBL:AF233395 xref: EMBL:AK002027 xref: EMBL:AL137626 xref: EMBL:BC017305 xref: EMBL:BC101791 xref: EMBL:BC101793 xref: HGNC:HGNC:14935 xref: UniGene:Hs.514636 xref: UniGene:Hs.528641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058895 ! SIRT7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019918 name: SIT1_human def: "Signaling threshold-regulating transmembrane adapter 1 precursor gene" [UniProtKB:Q9Y3P8] synonym: "SIT" EXACT [UniProtKB:Q9Y3P8] xref: EMBL:AJ010059 xref: EMBL:AJ271888 xref: EMBL:AL357874 xref: EMBL:BC102029 xref: EMBL:BC104491 xref: EMBL:BC107484 xref: HGNC:HGNC:17710 xref: UniGene:Hs.88012 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059342 ! SIT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019919 name: SIVA1_human def: "Apoptosis regulatory protein Siva gene" [UniProtKB:O15304] synonym: "SIVA" EXACT [UniProtKB:O15304] xref: EMBL:AF033111 xref: EMBL:AF401214 xref: EMBL:BC034562 xref: EMBL:BK000018 xref: EMBL:U82938 xref: HGNC:HGNC:17712 xref: UniGene:Hs.112058 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054423 ! SIVA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019920 name: SIX1_human def: "Homeobox protein SIX1 gene" [UniProtKB:Q15475] xref: EMBL:AF323497 xref: EMBL:BC008874 xref: EMBL:X91868 xref: HGNC:HGNC:10887 xref: UniGene:Hs.633506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056069 ! SIX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019921 name: SIX2_human def: "Homeobox protein SIX2 gene" [UniProtKB:Q9NPC8] xref: EMBL:AF136939 xref: EMBL:AF136940 xref: EMBL:AF323498 xref: EMBL:AF332196 xref: EMBL:AF332197 xref: EMBL:AF332198 xref: EMBL:BT020100 xref: HGNC:HGNC:10888 xref: UniGene:Hs.101937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058848 ! SIX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019922 name: SIX3_human def: "Homeobox protein SIX3 gene" [UniProtKB:O95343] xref: EMBL:AF049339 xref: EMBL:AF083891 xref: EMBL:AF092047 xref: EMBL:AJ012611 xref: HGNC:HGNC:10889 xref: UniGene:Hs.658847 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054749 ! SIX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019923 name: SIX4_human def: "Homeobox protein SIX4 gene" [UniProtKB:Q9UIU6] xref: EMBL:AB024687 xref: EMBL:BC098135 xref: HGNC:HGNC:10890 xref: UniGene:Hs.690393 xref: UniGene:Hs.97849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059164 ! SIX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019924 name: SIX5_human def: "Homeobox protein SIX5 gene" [UniProtKB:Q8N196] synonym: "DMAHP" EXACT [UniProtKB:Q8N196] xref: EMBL:AC074212 xref: EMBL:AK074826 xref: EMBL:BC033204 xref: EMBL:BU859227 xref: EMBL:X84813 xref: HGNC:HGNC:10891 xref: UniGene:Hs.43314 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057426 ! SIX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019925 name: SIX6_human def: "Homeobox protein SIX6 gene" [UniProtKB:O95475] synonym: "OPTX2" EXACT [UniProtKB:O95475] synonym: "SIX9" EXACT [UniProtKB:O95475] xref: EMBL:AB041399 xref: EMBL:AF031648 xref: EMBL:AF141651 xref: EMBL:AJ011785 xref: EMBL:BC065831 xref: EMBL:BC069413 xref: HGNC:HGNC:10892 xref: UniGene:Hs.194756 xref: UniGene:Hs.551925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054766 ! SIX6_HUMAN relationship: codes_for CCO:B0056875 ! Q6P051_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019926 name: SKAP1_human def: "Src kinase-associated phosphoprotein 1 gene" [UniProtKB:Q86WV1] synonym: "SCAP1" EXACT [UniProtKB:Q86WV1] synonym: "SKAP55" EXACT [UniProtKB:Q86WV1] xref: EMBL:BC047870 xref: EMBL:Y11215 xref: HGNC:HGNC:15605 xref: UniGene:Hs.316931 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057281 ! SKAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019927 name: SKAP2_human def: "Src kinase-associated phosphoprotein 2 gene" [UniProtKB:O75563] synonym: "PRAP" EXACT [UniProtKB:O75563] synonym: "RA70" EXACT [UniProtKB:O75563] synonym: "SAPS" EXACT [UniProtKB:O75563] synonym: "SCAP2" EXACT [UniProtKB:O75563] synonym: "SKAP55R" EXACT [UniProtKB:O75563] xref: EMBL:AB014486 xref: EMBL:AC003999 xref: EMBL:AC011299 xref: EMBL:AF051323 xref: EMBL:AF072166 xref: EMBL:AJ004886 xref: EMBL:AK222885 xref: EMBL:BC002893 xref: EMBL:BC036044 xref: HGNC:HGNC:15687 xref: UniGene:Hs.200770 xref: UniGene:Hs.696405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054650 ! SKAP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019928 name: SKIL_human def: "Ski-like protein gene" [UniProtKB:P12757] synonym: "SNO" EXACT [UniProtKB:P12757] xref: EMBL:AC073288 xref: EMBL:BC059386 xref: EMBL:U70730 xref: EMBL:X15217 xref: EMBL:X15219 xref: EMBL:Z19588 xref: HGNC:HGNC:10897 xref: UniGene:Hs.581632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055005 ! SKIL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019929 name: SKI_human def: "Ski oncogene gene" [UniProtKB:P12755] xref: EMBL:AL590822 xref: EMBL:X15218 xref: HGNC:HGNC:10896 xref: UniGene:Hs.705384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055004 ! SKI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019930 name: SLAMF1_human def: "Signaling lymphocytic activation molecule precursor gene" [UniProtKB:Q13291] synonym: "SLAM" EXACT [UniProtKB:Q13291] xref: EMBL:U33017 xref: HGNC:HGNC:10903 xref: UniGene:Hs.523660 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055894 ! SLAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019931 name: SLAMF7_human def: "SLAM family member 7 precursor gene" [UniProtKB:Q9NQ25] synonym: "CS1" EXACT [UniProtKB:Q9NQ25] synonym: "UNQ576/PRO1138" EXACT [UniProtKB:Q9NQ25] xref: EMBL:AB027233 xref: EMBL:AF291815 xref: EMBL:AF390894 xref: EMBL:AJ271869 xref: EMBL:AJ276429 xref: EMBL:AL121985 xref: EMBL:AL834424 xref: EMBL:AY358512 xref: EMBL:BC027867 xref: HGNC:HGNC:21394 xref: UniGene:Hs.517265 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058858 ! SLAF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019932 name: GINS4_human def: "DNA replication complex GINS protein SLD5 gene" [UniProtKB:Q9BRT9] synonym: "SLD5" EXACT [UniProtKB:Q9BRT9] xref: EMBL:BC005995 xref: EMBL:BC027454 xref: EMBL:CH471080 xref: HGNC:HGNC:28226 xref: UniGene:Hs.656996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058497 ! SLD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019933 name: GHRH_human def: "Somatoliberin precursor gene" [UniProtKB:P01286] synonym: "GHRF" EXACT [UniProtKB:P01286] xref: EMBL:AL031659 xref: EMBL:BC098109 xref: EMBL:BC099727 xref: EMBL:L00134 xref: EMBL:L00135 xref: EMBL:L00136 xref: EMBL:L00137 xref: EMBL:L29177 xref: EMBL:X00094 xref: HGNC:HGNC:4265 xref: UniGene:Hs.37023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054850 ! SLIB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019934 name: SLIRP_human def: "SRA stem-loop-interacting RNA-binding protein, mitochondrial precursor gene" [UniProtKB:Q9GZT3] synonym: "C14orf156" EXACT [UniProtKB:Q9GZT3] synonym: "DC23" EXACT [UniProtKB:Q9GZT3] synonym: "DC50" EXACT [UniProtKB:Q9GZT3] synonym: "PD04872" EXACT [UniProtKB:Q9GZT3] xref: EMBL:AF253980 xref: EMBL:AF271779 xref: EMBL:AJ272055 xref: EMBL:AY860853 xref: EMBL:BC017895 xref: HGNC:HGNC:20495 xref: UniGene:Hs.655105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058635 ! SLIRP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019935 name: SLIT2_human def: "Slit homolog 2 protein precursor gene" [UniProtKB:O94813] synonym: "SLIL3" EXACT [UniProtKB:O94813] xref: EMBL:AB017168 xref: EMBL:AF055585 xref: EMBL:AF133270 xref: EMBL:BC117190 xref: HGNC:HGNC:11086 xref: UniGene:Hs.699467 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027571 ! SLIT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019936 name: SLTM_human def: "SAFB-like transcription modulator gene" [UniProtKB:Q9NWH9] synonym: "MET" EXACT [UniProtKB:Q9NWH9] xref: EMBL:AC025918 xref: EMBL:AC090515 xref: EMBL:AK000867 xref: EMBL:AK023275 xref: EMBL:AK024710 xref: EMBL:AK131242 xref: EMBL:AL834297 xref: EMBL:BC014944 xref: EMBL:BC046119 xref: EMBL:BC108656 xref: HGNC:HGNC:20709 xref: UniGene:Hs.512932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058938 ! SLTM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019937 name: SMAD5OS_human def: "SMAD5 opposite strand protein gene" [UniProtKB:Q9Y6J3] synonym: "DAMS" EXACT [UniProtKB:Q9Y6J3] xref: EMBL:AF071111 xref: HGNC:HGNC:30586 xref: UniGene:Hs.59666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059408 ! SMA5O_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019938 name: SMAD1_human def: "Mothers against decapentaplegic homolog 1 gene" [UniProtKB:Q15797] synonym: "BSP1" EXACT [UniProtKB:Q15797] synonym: "MADH1" EXACT [UniProtKB:Q15797] synonym: "MADR1" EXACT [UniProtKB:Q15797] xref: EMBL:BC001878 xref: EMBL:BT007386 xref: EMBL:U54826 xref: EMBL:U57456 xref: EMBL:U59423 xref: EMBL:U59912 xref: HGNC:HGNC:6767 xref: UniGene:Hs.656534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056114 ! SMAD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019939 name: SMAD2_human def: "Mothers against decapentaplegic homolog 2 gene" [UniProtKB:Q15796] synonym: "MADH2" EXACT [UniProtKB:Q15796] synonym: "MADR2" EXACT [UniProtKB:Q15796] xref: EMBL:AF027964 xref: EMBL:BC014840 xref: EMBL:BC025699 xref: EMBL:U59911 xref: EMBL:U65019 xref: EMBL:U68018 xref: EMBL:U78727 xref: EMBL:U78728 xref: EMBL:U78729 xref: EMBL:U78730 xref: EMBL:U78731 xref: EMBL:U78732 xref: EMBL:U78733 xref: HGNC:HGNC:6768 xref: UniGene:Hs.12253 xref: UniGene:Hs.705764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056113 ! SMAD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019940 name: SMAD5_human def: "Mothers against decapentaplegic homolog 5 gene" [UniProtKB:Q99717] synonym: "MADH5" EXACT [UniProtKB:Q99717] xref: EMBL:AF009678 xref: EMBL:AF009739 xref: EMBL:AF009740 xref: EMBL:AF009741 xref: EMBL:AF009742 xref: EMBL:AF009743 xref: EMBL:AF009744 xref: EMBL:AF010601 xref: EMBL:AF010602 xref: EMBL:AF010603 xref: EMBL:AF010604 xref: EMBL:AF010605 xref: EMBL:AF010606 xref: EMBL:AF010607 xref: EMBL:BC009682 xref: EMBL:U59913 xref: EMBL:U73825 xref: HGNC:HGNC:6771 xref: UniGene:Hs.167700 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058446 ! SMAD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019941 name: SMAD6_human def: "Mothers against decapentaplegic homolog 6 gene" [UniProtKB:O43541] synonym: "MADH6" EXACT [UniProtKB:O43541] xref: EMBL:AF035528 xref: EMBL:AF037469 xref: EMBL:AF041062 xref: EMBL:AF041063 xref: EMBL:AF041064 xref: EMBL:AF041065 xref: EMBL:AF043640 xref: EMBL:AF101474 xref: EMBL:AM909653 xref: EMBL:BC012986 xref: EMBL:BC052569 xref: EMBL:U59914 xref: HGNC:HGNC:6772 xref: UniGene:Hs.153863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054488 ! SMAD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019942 name: SMAD7_human def: "Mothers against decapentaplegic homolog 7 gene" [UniProtKB:O15105] synonym: "MADH7" EXACT [UniProtKB:O15105] synonym: "MADH8" EXACT [UniProtKB:O15105] xref: EMBL:AF010193 xref: EMBL:AF015261 xref: EMBL:AF026556 xref: EMBL:AF026557 xref: EMBL:AF026558 xref: EMBL:AF026559 xref: EMBL:BC074818 xref: EMBL:BC074819 xref: HGNC:HGNC:6773 xref: UniGene:Hs.465087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054406 ! SMAD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019943 name: SMAD9_human def: "Mothers against decapentaplegic homolog 9 gene" [UniProtKB:O15198] synonym: "MADH6" EXACT [UniProtKB:O15198] synonym: "MADH9" EXACT [UniProtKB:O15198] xref: EMBL:BC011559 xref: EMBL:D83760 xref: EMBL:D83761 xref: HGNC:HGNC:6774 xref: UniGene:Hs.123119 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054414 ! SMAD9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019944 name: SMARCAL1_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 gene" [UniProtKB:Q9NZC9] synonym: "HARP" EXACT [UniProtKB:Q9NZC9] xref: EMBL:AC098820 xref: EMBL:AF082179 xref: EMBL:AF210833 xref: EMBL:AF210834 xref: EMBL:AF210835 xref: EMBL:AF210836 xref: EMBL:AF210837 xref: EMBL:AF210838 xref: EMBL:AF210839 xref: EMBL:AF210840 xref: EMBL:AF210841 xref: EMBL:AF210842 xref: EMBL:AF432223 xref: EMBL:AK000117 xref: EMBL:AL122076 xref: EMBL:BC016482 xref: EMBL:BC043341 xref: EMBL:CH471063 xref: HGNC:HGNC:11102 xref: UniGene:Hs.516674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058992 ! SMAL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019945 name: IGHMBP2_human def: "DNA-binding protein SMUBP-2 gene" [UniProtKB:P38935] synonym: "SMBP2" EXACT [UniProtKB:P38935] synonym: "SMUBP2" EXACT [UniProtKB:P38935] xref: EMBL:L14754 xref: EMBL:L24544 xref: EMBL:M64979 xref: HGNC:HGNC:5542 xref: UniGene:Hs.503048 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055321 ! SMBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019946 name: SFMBT1_human def: "Scm-like with four MBT domains protein 1 gene" [UniProtKB:Q9UHJ3] synonym: "RU1" EXACT [UniProtKB:Q9UHJ3] xref: EMBL:AF168132 xref: EMBL:AL080140 xref: EMBL:BC014614 xref: HGNC:HGNC:20255 xref: UniGene:Hs.343679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059142 ! SMBT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019947 name: SFMBT2_human def: "Scm-like with four MBT domains protein 2 gene" [UniProtKB:Q5VUG0] synonym: "KIAA1617" EXACT [UniProtKB:Q5VUG0] xref: EMBL:AB046837 xref: EMBL:AL138771 xref: EMBL:AL139125 xref: EMBL:AL158046 xref: EMBL:AL590095 xref: HGNC:HGNC:20256 xref: UniGene:Hs.407983 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056597 ! Q5T980_HUMAN relationship: codes_for CCO:B0056598 ! Q5T981_HUMAN relationship: codes_for CCO:B0056655 ! SMBT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019948 name: SMARCA1_human def: "Probable global transcription activator SNF2L1 gene" [UniProtKB:P28370] synonym: "SNF2L" EXACT [UniProtKB:P28370] synonym: "SNF2L1" EXACT [UniProtKB:P28370] xref: EMBL:AL022577 xref: EMBL:AL138745 xref: EMBL:BC117447 xref: EMBL:M88163 xref: EMBL:M89907 xref: HGNC:HGNC:11097 xref: UniGene:Hs.152292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055204 ! SMCA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019949 name: SMARCA5_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 gene" [UniProtKB:O60264] synonym: "SNF2H" EXACT [UniProtKB:O60264] synonym: "WCRF135" EXACT [UniProtKB:O60264] xref: EMBL:AB010882 xref: EMBL:BC023144 xref: HGNC:HGNC:11101 xref: UniGene:Hs.589489 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054538 ! SMCA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019950 name: SMF_human def: "Protein SMF gene" [UniProtKB:Q12766] synonym: "KIAA0194" EXACT [UniProtKB:Q12766] xref: EMBL:AC011406 xref: EMBL:BC051025 xref: EMBL:D83778 xref: EMBL:U63963 xref: UniGene:Hs.586219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055837 ! SMF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019951 name: SMG5_human def: "Protein SMG5 gene" [UniProtKB:Q9UPR3] synonym: "EST1B" EXACT [UniProtKB:Q9UPR3] synonym: "KIAA1089" EXACT [UniProtKB:Q9UPR3] xref: EMBL:AB029012 xref: EMBL:AB085691 xref: EMBL:AL135927 xref: EMBL:AL137738 xref: EMBL:AL589685 xref: EMBL:AY168922 xref: EMBL:AY336728 xref: EMBL:BC007453 xref: EMBL:BC038296 xref: HGNC:HGNC:24644 xref: UniGene:Hs.516837 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059266 ! SMG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019952 name: SMG7_human def: "Protein SMG7 gene" [UniProtKB:Q92540] synonym: "C1orf16" EXACT [UniProtKB:Q92540] synonym: "EST1C" EXACT [UniProtKB:Q92540] synonym: "KIAA0250" EXACT [UniProtKB:Q92540] xref: EMBL:AB085674 xref: EMBL:AL137800 xref: EMBL:AL449223 xref: EMBL:BC036381 xref: EMBL:BC052565 xref: EMBL:D87437 xref: HGNC:HGNC:16792 xref: UniGene:Hs.591463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058061 ! SMG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019953 name: SMARCAD1_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 gene" [UniProtKB:Q9H4L7] synonym: "KIAA1122" EXACT [UniProtKB:Q9H4L7] xref: EMBL:AB032948 xref: EMBL:AK023990 xref: EMBL:AK027490 xref: EMBL:AL359929 xref: EMBL:AL512768 xref: EMBL:AY008271 xref: EMBL:BC045534 xref: HGNC:HGNC:18398 xref: UniGene:Hs.410406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058717 ! SMRCD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019954 name: SMARCD3_human def: "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 gene" [UniProtKB:Q6STE5] synonym: "BAF60C" EXACT [UniProtKB:Q6STE5] xref: EMBL:AC005486 xref: EMBL:AC021097 xref: EMBL:AY450430 xref: EMBL:AY450431 xref: EMBL:BC002628 xref: EMBL:U66619 xref: HGNC:HGNC:11108 xref: UniGene:Hs.647067 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056941 ! SMRD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019955 name: SST_human def: "Somatostatin precursor gene" [UniProtKB:P61278] xref: EMBL:BC032625 xref: EMBL:J00306 xref: HGNC:HGNC:11329 xref: UniGene:Hs.12409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055607 ! SMS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019956 name: SMURF1_human def: "E3 ubiquitin-protein ligase SMURF1 gene" [UniProtKB:Q9HCE7] synonym: "KIAA1625" EXACT [UniProtKB:Q9HCE7] xref: EMBL:AB046845 xref: EMBL:AC004893 xref: EMBL:AC073468 xref: EMBL:AC114500 xref: EMBL:AF199364 xref: HGNC:HGNC:16807 xref: UniGene:Hs.189329 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058805 ! SMUF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019957 name: SMURF2_human def: "E3 ubiquitin-protein ligase SMURF2 gene" [UniProtKB:Q9HAU4] xref: EMBL:AF301463 xref: EMBL:AF310676 xref: EMBL:AY014180 xref: EMBL:BC093876 xref: EMBL:BC111945 xref: HGNC:HGNC:16809 xref: UniGene:Hs.705442 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058768 ! SMUF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019958 name: SMYD1_human def: "SET and MYND domain-containing protein 1 gene" [UniProtKB:Q8NB12] xref: EMBL:AC092836 xref: EMBL:AK091724 xref: EMBL:AL832035 xref: EMBL:BC126191 xref: HGNC:HGNC:20986 xref: UniGene:Hs.516176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057552 ! SMYD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019959 name: NAPG_human def: "Gamma-soluble NSF attachment protein gene" [UniProtKB:Q99747] synonym: "SNAPG" EXACT [UniProtKB:Q99747] xref: EMBL:BC001889 xref: EMBL:U78107 xref: HGNC:HGNC:7642 xref: UniGene:Hs.464622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058452 ! SNAG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019960 name: SNAI2_human def: "Zinc finger protein SNAI2 gene" [UniProtKB:O43623] synonym: "SLUG" EXACT [UniProtKB:O43623] synonym: "SLUGH" EXACT [UniProtKB:O43623] xref: EMBL:AF042001 xref: EMBL:AF084243 xref: EMBL:BC014890 xref: EMBL:BC015895 xref: HGNC:HGNC:11094 xref: UniGene:Hs.360174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054504 ! SNAI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019961 name: SNAI3_human def: "Zinc finger protein SNAI3 gene" [UniProtKB:Q3KNW1] synonym: "ZNF293" EXACT [UniProtKB:Q3KNW1] xref: EMBL:BC041461 xref: EMBL:BC107058 xref: EMBL:CH471184 xref: HGNC:HGNC:18411 xref: UniGene:Hs.499548 xref: UniGene:Hs.673548 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056252 ! SNAI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019962 name: SND1_human def: "Staphylococcal nuclease domain-containing protein 1 gene" [UniProtKB:Q7KZF4] synonym: "TDRD11" EXACT [UniProtKB:Q7KZF4] xref: EMBL:BC017180 xref: EMBL:BT009785 xref: EMBL:U22055 xref: HGNC:HGNC:30646 xref: UniGene:Hs.122523 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057111 ! SND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019963 name: SNAP25_human def: "Synaptosomal-associated protein 25 gene" [UniProtKB:P60880] synonym: "SNAP" EXACT [UniProtKB:P60880] xref: EMBL:AL023913 xref: EMBL:BC010647 xref: EMBL:D21267 xref: EMBL:L19760 xref: EMBL:L19761 xref: HGNC:HGNC:11132 xref: UniGene:Hs.167317 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055598 ! SNP25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019964 name: SNAPC1_human def: "snRNA-activating protein complex subunit 1 gene" [UniProtKB:Q16533] synonym: "SNAP43" EXACT [UniProtKB:Q16533] xref: EMBL:BC014984 xref: EMBL:BC019038 xref: EMBL:U44754 xref: EMBL:Z47542 xref: HGNC:HGNC:11134 xref: UniGene:Hs.179312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056144 ! SNPC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019965 name: SNAPC2_human def: "snRNA-activating protein complex subunit 2 gene" [UniProtKB:Q13487] synonym: "SNAP45" EXACT [UniProtKB:Q13487] xref: EMBL:BC011868 xref: EMBL:U44755 xref: EMBL:U44898 xref: HGNC:HGNC:11135 xref: UniGene:Hs.631860 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055915 ! SNPC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019966 name: SNAPC3_human def: "snRNA-activating protein complex subunit 3 gene" [UniProtKB:Q92966] synonym: "SNAP50" EXACT [UniProtKB:Q92966] xref: EMBL:AL441925 xref: EMBL:BC014985 xref: EMBL:BC108743 xref: EMBL:BC121011 xref: EMBL:BC121012 xref: EMBL:U66413 xref: EMBL:U71300 xref: HGNC:HGNC:11136 xref: UniGene:Hs.546299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058116 ! SNPC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019967 name: SNAPC4_human def: "snRNA-activating protein complex subunit 4 gene" [UniProtKB:Q5SXM2] synonym: "SNAP190" EXACT [UniProtKB:Q5SXM2] xref: EMBL:AF032387 xref: EMBL:AL592301 xref: HGNC:HGNC:11137 xref: UniGene:Hs.113265 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056550 ! SNPC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019968 name: SNAPC5_human def: "snRNA-activating protein complex subunit 5 gene" [UniProtKB:O75971] synonym: "SNAP19" EXACT [UniProtKB:O75971] xref: EMBL:AF093593 xref: EMBL:BC014315 xref: HGNC:HGNC:15484 xref: UniGene:Hs.30174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054683 ! SNPC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019969 name: SNX13_human def: "Sorting nexin-13 gene" [UniProtKB:Q9Y5W8] synonym: "KIAA0713" EXACT [UniProtKB:Q9Y5W8] xref: EMBL:AB018256 xref: EMBL:AF121862 xref: EMBL:AF420470 xref: EMBL:BC022060 xref: HGNC:HGNC:21335 xref: UniGene:Hs.585343 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059390 ! SNX13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019970 name: SNX17_human def: "Sorting nexin-17 gene" [UniProtKB:Q15036] synonym: "KIAA0064" EXACT [UniProtKB:Q15036] xref: EMBL:AC074117 xref: EMBL:AJ404855 xref: EMBL:AJ404856 xref: EMBL:AK222543 xref: EMBL:BC002524 xref: EMBL:BC002610 xref: EMBL:BC014620 xref: EMBL:BC050590 xref: EMBL:BT007167 xref: EMBL:CR457081 xref: EMBL:D31764 xref: HGNC:HGNC:14979 xref: UniGene:Hs.278569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056037 ! SNX17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019971 name: SNX27_human def: "Sorting nexin-27 gene" [UniProtKB:Q96L92] synonym: "KIAA0488" EXACT [UniProtKB:Q96L92] synonym: "My014" EXACT [UniProtKB:Q96L92] xref: EMBL:AB007957 xref: EMBL:AF060509 xref: EMBL:AL391335 xref: EMBL:AL589765 xref: EMBL:AY044866 xref: EMBL:BC012184 xref: EMBL:BC051817 xref: EMBL:BC071825 xref: EMBL:BC100998 xref: EMBL:BC100999 xref: EMBL:BC101000 xref: EMBL:BC101822 xref: EMBL:BC101824 xref: EMBL:BC107862 xref: HGNC:HGNC:20073 xref: UniGene:Hs.192326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053935 ! A6PVX5_HUMAN relationship: codes_for CCO:B0058267 ! SNX27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019972 name: SOCS1_human def: "Suppressor of cytokine signaling 1 gene" [UniProtKB:O15524] synonym: "SSI1" EXACT [UniProtKB:O15524] synonym: "TIP3" EXACT [UniProtKB:O15524] xref: EMBL:AB000676 xref: EMBL:AB000734 xref: EMBL:AB005043 xref: EMBL:AF132440 xref: EMBL:U88326 xref: EMBL:Z46940 xref: HGNC:HGNC:19383 xref: UniGene:Hs.50640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054443 ! SOCS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019973 name: SOCS2_human def: "Suppressor of cytokine signaling 2 gene" [UniProtKB:O14508] synonym: "CIS2" EXACT [UniProtKB:O14508] synonym: "SSI2" EXACT [UniProtKB:O14508] synonym: "STATI2" EXACT [UniProtKB:O14508] xref: EMBL:AB004903 xref: EMBL:AB006966 xref: EMBL:AF020590 xref: EMBL:AF037989 xref: EMBL:AF132441 xref: EMBL:BC010399 xref: HGNC:HGNC:19382 xref: UniGene:Hs.485572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054345 ! SOCS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019974 name: SOCS4_human def: "Suppressor of cytokine signaling 4 gene" [UniProtKB:Q8WXH5] synonym: "SOCS7" EXACT [UniProtKB:Q8WXH5] xref: EMBL:AF424815 xref: EMBL:BC060790 xref: HGNC:HGNC:19392 xref: UniGene:Hs.700908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058020 ! SOCS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019975 name: SOCS5_human def: "Suppressor of cytokine signaling 5 gene" [UniProtKB:O75159] synonym: "CIS6" EXACT [UniProtKB:O75159] synonym: "CISH5" EXACT [UniProtKB:O75159] synonym: "CISH6" EXACT [UniProtKB:O75159] synonym: "KIAA0671" EXACT [UniProtKB:O75159] xref: EMBL:AB014571 xref: EMBL:AF073958 xref: EMBL:AL136896 xref: EMBL:BC032862 xref: HGNC:HGNC:16852 xref: UniGene:Hs.468426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054608 ! SOCS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019976 name: SOCS6_human def: "Suppressor of cytokine signaling 6 gene" [UniProtKB:O14544] synonym: "CIS4" EXACT [UniProtKB:O14544] synonym: "SOCS4" EXACT [UniProtKB:O14544] xref: EMBL:AB006968 xref: EMBL:BC020082 xref: EMBL:CH471117 xref: HGNC:HGNC:16833 xref: UniGene:Hs.44439 xref: UniGene:Hs.705689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054349 ! SOCS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019977 name: SOCS7_human def: "Suppressor of cytokine signaling 7 gene" [UniProtKB:O14512] synonym: "NAP4" EXACT [UniProtKB:O14512] synonym: "SOCS6" EXACT [UniProtKB:O14512] xref: EMBL:AB005216 xref: EMBL:AC115992 xref: EMBL:AC124789 xref: EMBL:BC128607 xref: HGNC:HGNC:29846 xref: UniGene:Hs.632261 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054347 ! SOCS7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019978 name: SOHLH1_human def: "Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 gene" [UniProtKB:Q5JUK2] synonym: "C9orf157" EXACT [UniProtKB:Q5JUK2] synonym: "NOHLH" EXACT [UniProtKB:Q5JUK2] synonym: "TEB2" EXACT [UniProtKB:Q5JUK2] xref: EMBL:AL158822 xref: EMBL:AY884306 xref: EMBL:AY902244 xref: EMBL:BC031861 xref: EMBL:CH471090 xref: HGNC:HGNC:27845 xref: UniGene:Hs.120464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056489 ! SOLH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019979 name: SOHLH2_human def: "Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 gene" [UniProtKB:Q9NX45] synonym: "TEB1" EXACT [UniProtKB:Q9NX45] xref: EMBL:AK000456 xref: EMBL:AL160392 xref: EMBL:AY884305 xref: EMBL:BC025383 xref: EMBL:CH471075 xref: HGNC:HGNC:26026 xref: UniGene:Hs.124519 xref: UniGene:Hs.646618 xref: UniGene:Hs.656745 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058947 ! SOLH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019980 name: SOLO_human def: "Protein SOLO gene" [UniProtKB:Q8TER5] xref: EMBL:AK001219 xref: EMBL:AK024463 xref: EMBL:AK074057 xref: EMBL:AL137291 xref: EMBL:BC000084 xref: EMBL:BC142692 xref: UniGene:Hs.35125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057955 ! SOLO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019981 name: GH1_human def: "Somatotropin precursor gene" [UniProtKB:P01241] xref: EMBL:A00469 xref: EMBL:A12770 xref: EMBL:AF110644 xref: EMBL:AF185611 xref: EMBL:BC062475 xref: EMBL:BC075012 xref: EMBL:BC075013 xref: EMBL:BC090045 xref: EMBL:J03071 xref: EMBL:M13438 xref: EMBL:M14398 xref: EMBL:V00519 xref: EMBL:V00520 xref: HGNC:HGNC:4261 xref: UniGene:Hs.654390 xref: UniGene:Hs.655229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054843 ! SOMA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019982 name: SON_human def: "SON protein gene" [UniProtKB:P18583] synonym: "C21orf50" EXACT [UniProtKB:P18583] synonym: "DBP5" EXACT [UniProtKB:P18583] synonym: "KIAA1019" EXACT [UniProtKB:P18583] synonym: "NREBP" EXACT [UniProtKB:P18583] xref: EMBL:AB028942 xref: EMBL:AF139897 xref: EMBL:AF161428 xref: EMBL:AF161430 xref: EMBL:AF380179 xref: EMBL:AF380180 xref: EMBL:AF380181 xref: EMBL:AF380182 xref: EMBL:AF380183 xref: EMBL:AF380184 xref: EMBL:AF435977 xref: EMBL:AK024752 xref: EMBL:AY026895 xref: EMBL:M36428 xref: EMBL:X63071 xref: EMBL:X63751 xref: EMBL:X63753 xref: HGNC:HGNC:11183 xref: UniGene:Hs.517262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055101 ! SON_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019983 name: SORCS1_human def: "VPS10 domain-containing receptor SorCS1 precursor gene" [UniProtKB:Q8WY21] synonym: "SORCS" EXACT [UniProtKB:Q8WY21] xref: EMBL:AB209142 xref: EMBL:AF284756 xref: EMBL:AL133395 xref: EMBL:AL160010 xref: EMBL:AL356255 xref: EMBL:AL356308 xref: EMBL:AL357333 xref: EMBL:AY099452 xref: EMBL:AY099453 xref: HGNC:HGNC:16697 xref: UniGene:Hs.591915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026865 ! SORC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019984 name: SORCS2_human def: "VPS10 domain-containing receptor SorCS2 precursor gene" [UniProtKB:Q96PQ0] synonym: "KIAA1329" EXACT [UniProtKB:Q96PQ0] xref: EMBL:AB037750 xref: EMBL:AC097382 xref: EMBL:AF286190 xref: HGNC:HGNC:16698 xref: UniGene:Hs.479099 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026867 ! SORC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019985 name: SORCS3_human def: "VPS10 domain-containing receptor SorCS3 precursor gene" [UniProtKB:Q9UPU3] synonym: "KIAA1059" EXACT [UniProtKB:Q9UPU3] xref: EMBL:AB028982 xref: EMBL:AL161646 xref: EMBL:AL353900 xref: EMBL:AL358949 xref: EMBL:AL365449 xref: EMBL:AL445492 xref: EMBL:AL596118 xref: HGNC:HGNC:16699 xref: UniGene:Hs.671950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026866 ! SORC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019986 name: SORT1_human def: "Sortilin precursor gene" [UniProtKB:Q99523] xref: EMBL:AL390252 xref: EMBL:BC023542 xref: EMBL:X98248 xref: HGNC:HGNC:11186 xref: UniGene:Hs.485195 xref: UniGene:Hs.703487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058421 ! SORT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019987 name: SOSTDC1_human def: "Sclerostin domain-containing protein 1 precursor gene" [UniProtKB:Q6X4U4] synonym: "CDA019" EXACT [UniProtKB:Q6X4U4] synonym: "USAG1" EXACT [UniProtKB:Q6X4U4] xref: EMBL:AB059270 xref: EMBL:AC079155 xref: EMBL:AF361494 xref: EMBL:AL050024 xref: EMBL:AY255634 xref: EMBL:BC008484 xref: HGNC:HGNC:21748 xref: UniGene:Hs.648106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056970 ! SOSD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019988 name: SOST_human def: "Sclerostin precursor gene" [UniProtKB:Q9BQB4] synonym: "UNQ2976/PRO7455/PRO7476" EXACT [UniProtKB:Q9BQB4] xref: EMBL:AF326736 xref: EMBL:AF326739 xref: EMBL:AF331844 xref: EMBL:AY358203 xref: EMBL:AY358627 xref: EMBL:BC101086 xref: EMBL:BC101087 xref: EMBL:BC101088 xref: EMBL:BC101089 xref: HGNC:HGNC:13771 xref: UniGene:Hs.349204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058479 ! SOST_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019989 name: SOX10_human def: "Transcription factor SOX-10 gene" [UniProtKB:P56693] xref: EMBL:AJ001183 xref: EMBL:AL031587 xref: EMBL:BC002824 xref: EMBL:BC007595 xref: EMBL:BT020029 xref: EMBL:CR456584 xref: HGNC:HGNC:11190 xref: UniGene:Hs.376984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053924 ! A6PVD2_HUMAN relationship: codes_for CCO:B0053925 ! A6PVD3_HUMAN relationship: codes_for CCO:B0055547 ! SOX10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019990 name: SOX13_human def: "SOX-13 protein gene" [UniProtKB:Q9UN79] xref: EMBL:AF083105 xref: EMBL:AF098915 xref: EMBL:AF116571 xref: EMBL:AF149301 xref: EMBL:BC106038 xref: EMBL:CH471067 xref: HGNC:HGNC:11192 xref: UniGene:Hs.201671 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056255 ! Q3KQV7_HUMAN relationship: codes_for CCO:B0059247 ! SOX13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019991 name: SOX5_human def: "Transcription factor SOX-5 gene" [UniProtKB:P35711] xref: EMBL:AB081588 xref: EMBL:AB081589 xref: EMBL:AB081590 xref: EMBL:AB081591 xref: EMBL:AK074317 xref: EMBL:AK098610 xref: EMBL:BC029220 xref: EMBL:BC035227 xref: EMBL:BC047665 xref: EMBL:BC060773 xref: EMBL:S83308 xref: EMBL:X65662 xref: HGNC:HGNC:11201 xref: UniGene:Hs.657542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055300 ! SOX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019992 name: SOX6_human def: "Transcription factor SOX-6 gene" [UniProtKB:P35712] xref: EMBL:AC009869 xref: EMBL:AC013595 xref: EMBL:AC027016 xref: EMBL:AC068405 xref: EMBL:AC103794 xref: EMBL:AF309034 xref: EMBL:AF309471 xref: EMBL:AF309472 xref: EMBL:AF309473 xref: EMBL:AF309474 xref: EMBL:AF309475 xref: EMBL:AF309476 xref: EMBL:AL136780 xref: EMBL:BC047064 xref: EMBL:CH471064 xref: EMBL:X65663 xref: HGNC:HGNC:16421 xref: UniGene:Hs.368226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054003 ! A8MRT1_HUMAN relationship: codes_for CCO:B0055301 ! SOX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019993 name: SOX7_human def: "Transcription factor SOX-7 gene" [UniProtKB:Q9BT81] xref: EMBL:AJ409320 xref: EMBL:AK055556 xref: EMBL:BC071947 xref: HGNC:HGNC:18196 xref: UniGene:Hs.490991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058513 ! SOX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019994 name: SOX8_human def: "Transcription factor SOX-8 gene" [UniProtKB:P57073] xref: EMBL:AE006465 xref: EMBL:AF164104 xref: EMBL:AF226675 xref: EMBL:BC031797 xref: EMBL:Z99757 xref: HGNC:HGNC:11203 xref: UniGene:Hs.243678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055557 ! SOX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019995 name: SOX9_human def: "Transcription factor SOX-9 gene" [UniProtKB:P48436] xref: EMBL:BC007951 xref: EMBL:BC056420 xref: EMBL:S74504 xref: EMBL:S74505 xref: EMBL:S74506 xref: EMBL:Z46629 xref: HGNC:HGNC:11204 xref: UniGene:Hs.700579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055403 ! SOX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019996 name: SP100_human def: "Nuclear autoantigen Sp-100 gene" [UniProtKB:P23497] xref: EMBL:AF056322 xref: EMBL:AF076675 xref: EMBL:AF255565 xref: EMBL:AF378670 xref: EMBL:BC011562 xref: EMBL:L79987 xref: EMBL:L79988 xref: EMBL:M60618 xref: EMBL:U36501 xref: EMBL:X95472 xref: HGNC:HGNC:11206 xref: UniGene:Hs.369056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055159 ! SP100_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019997 name: SP110_human def: "Sp110 nuclear body protein gene" [UniProtKB:Q9HB58] xref: EMBL:AC009950 xref: EMBL:AF280094 xref: EMBL:AF280095 xref: EMBL:AK026488 xref: EMBL:BC019059 xref: EMBL:CH471063 xref: EMBL:L22342 xref: EMBL:L22343 xref: HGNC:HGNC:5401 xref: UniGene:Hs.145150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058777 ! SP110_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019998 name: SAP130_human def: "Histone deacetylase complex subunit SAP130 gene" [UniProtKB:Q9H0E3] xref: EMBL:AC012306 xref: EMBL:AC118060 xref: EMBL:AK022823 xref: EMBL:AL136833 xref: EMBL:AY220791 xref: EMBL:BC017453 xref: EMBL:BC117255 xref: HGNC:HGNC:29813 xref: UniGene:Hs.32995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058650 ! SP130_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0019999 name: SPA17_human def: "Sperm surface protein Sp17 gene" [UniProtKB:Q15506] synonym: "SP17" EXACT [UniProtKB:Q15506] xref: EMBL:AF334735 xref: EMBL:AF334810 xref: EMBL:BC032457 xref: EMBL:Z48570 xref: HGNC:HGNC:11210 xref: UniGene:Hs.286233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056071 ! SP17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020000 name: SP2_human def: "Transcription factor Sp2 gene" [UniProtKB:Q02086] synonym: "KIAA0048" EXACT [UniProtKB:Q02086] xref: EMBL:AC018521 xref: EMBL:BC016680 xref: EMBL:BC033814 xref: EMBL:CH471109 xref: EMBL:D28588 xref: EMBL:M97190 xref: HGNC:HGNC:11207 xref: UniGene:Hs.514276 xref: UniGene:Hs.706144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055704 ! SP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020001 name: SAP30L_human def: "Histone deacetylase complex subunit SAP30L gene" [UniProtKB:Q9HAJ7] synonym: "NS4ATP2" EXACT [UniProtKB:Q9HAJ7] xref: EMBL:AK021588 xref: EMBL:AY341060 xref: EMBL:AY846876 xref: EMBL:BC009829 xref: EMBL:CH471062 xref: HGNC:HGNC:25663 xref: UniGene:Hs.483906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058763 ! SP30L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020002 name: SP3_human def: "Transcription factor Sp3 gene" [UniProtKB:Q02447] xref: EMBL:AF494280 xref: EMBL:AJ310752 xref: EMBL:AY070137 xref: EMBL:AY441957 xref: EMBL:AY441958 xref: EMBL:BC126414 xref: EMBL:M97191 xref: EMBL:X68560 xref: HGNC:HGNC:11208 xref: UniGene:Hs.531587 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055710 ! SP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020003 name: SP4_human def: "Transcription factor Sp4 gene" [UniProtKB:Q02446] xref: EMBL:AC004595 xref: EMBL:X68561 xref: HGNC:HGNC:11209 xref: UniGene:Hs.88013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055709 ! SP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020004 name: SP5_human def: "Transcription factor Sp5 gene" [UniProtKB:Q6BEB4] xref: EMBL:AB096175 xref: HGNC:HGNC:14529 xref: UniGene:Hs.368802 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056720 ! SP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020005 name: SP6_human def: "Transcription factor Sp6 gene" [UniProtKB:Q3SY56] synonym: "KLF14" EXACT [UniProtKB:Q3SY56] xref: EMBL:BC103951 xref: EMBL:BC103952 xref: EMBL:BC103953 xref: EMBL:BC103954 xref: HGNC:HGNC:14530 xref: UniGene:Hs.253603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056270 ! SP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020006 name: SP7_human def: "Transcription factor Sp7 gene" [UniProtKB:Q8TDD2] synonym: "OSX" EXACT [UniProtKB:Q8TDD2] xref: EMBL:AF466179 xref: EMBL:AF477981 xref: EMBL:AY150673 xref: EMBL:BC101549 xref: EMBL:BC113613 xref: HGNC:HGNC:17321 xref: UniGene:Hs.209402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057926 ! SP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020007 name: SERPINB13_human def: "Serpin B13 gene" [UniProtKB:Q9UIV8] synonym: "PI13" EXACT [UniProtKB:Q9UIV8] xref: EMBL:AF169949 xref: EMBL:AF216854 xref: EMBL:AJ001696 xref: EMBL:AJ001697 xref: EMBL:AJ001698 xref: EMBL:AJ278717 xref: EMBL:BC101821 xref: HGNC:HGNC:8944 xref: UniGene:Hs.241407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059165 ! SPB13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020008 name: SERPINB4_human def: "Serpin B4 gene" [UniProtKB:P48594] synonym: "SCCA2" EXACT [UniProtKB:P48594] xref: EMBL:AB035089 xref: EMBL:BC017401 xref: EMBL:U19557 xref: EMBL:U19570 xref: EMBL:U19571 xref: EMBL:U19572 xref: EMBL:U19574 xref: EMBL:U19575 xref: EMBL:U19576 xref: EMBL:X89015 xref: HGNC:HGNC:10570 xref: UniGene:Hs.123035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055408 ! SPB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020009 name: SEPSECS_human def: "O-phosphoseryl-tRNA(Sec) selenium transferase gene" [UniProtKB:Q9HD40] synonym: "TRNP48" EXACT [UniProtKB:Q9HD40] xref: EMBL:AF146396 xref: EMBL:AF282065 xref: EMBL:AJ238617 xref: EMBL:AJ277541 xref: EMBL:BX648976 xref: HGNC:HGNC:30605 xref: UniGene:Hs.253305 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026033 ! SPCS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020010 name: SPDEF_human def: "SAM pointed domain-containing Ets transcription factor gene" [UniProtKB:O95238] synonym: "PDEF" EXACT [UniProtKB:O95238] synonym: "PSE" EXACT [UniProtKB:O95238] xref: EMBL:AB031549 xref: EMBL:AF071538 xref: EMBL:BC021299 xref: EMBL:BX255971 xref: EMBL:BX255972 xref: EMBL:BX255973 xref: HGNC:HGNC:17257 xref: UniGene:Hs.485158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054739 ! SPDEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020011 name: SPEG_human def: "Striated muscle preferentially expressed protein kinase gene" [UniProtKB:Q15772] synonym: "APEG1" EXACT [UniProtKB:Q15772] synonym: "KIAA1297" EXACT [UniProtKB:Q15772] xref: EMBL:AB037718 xref: EMBL:AC053503 xref: EMBL:AK126500 xref: EMBL:AK128689 xref: EMBL:AY603755 xref: EMBL:BC006346 xref: EMBL:CR542201 xref: EMBL:DQ395348 xref: EMBL:U57099 xref: HGNC:HGNC:16901 xref: UniGene:Hs.21639 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056109 ! SPEG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020012 name: SMNDC1_human def: "Survival of motor neuron-related-splicing factor 30 gene" [UniProtKB:O75940] synonym: "SMNR" EXACT [UniProtKB:O75940] synonym: "SPF30" EXACT [UniProtKB:O75940] xref: EMBL:AF083385 xref: EMBL:AF107463 xref: EMBL:AL360182 xref: EMBL:BC011234 xref: HGNC:HGNC:16900 xref: UniGene:Hs.702187 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054679 ! SPF30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020013 name: SPG21_human def: "Maspardin gene" [UniProtKB:Q9NZD8] synonym: "ACP33" EXACT [UniProtKB:Q9NZD8] synonym: "BM-019" EXACT [UniProtKB:Q9NZD8] synonym: "GL010" EXACT [UniProtKB:Q9NZD8] xref: EMBL:AF208861 xref: EMBL:AF212231 xref: EMBL:AK172849 xref: EMBL:BC000244 xref: HGNC:HGNC:20373 xref: UniGene:Hs.242458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058995 ! SPG21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020014 name: SPI1_human def: "Transcription factor PU.1 gene" [UniProtKB:P17947] xref: EMBL:X52056 xref: HGNC:HGNC:11241 xref: UniGene:Hs.502511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055095 ! SPI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020015 name: SPIB_human def: "Transcription factor Spi-B gene" [UniProtKB:Q01892] xref: EMBL:BC007921 xref: EMBL:X66079 xref: EMBL:X96998 xref: HGNC:HGNC:11242 xref: UniGene:Hs.437905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055695 ! SPIB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020016 name: SPIC_human def: "Transcription factor Spi-C gene" [UniProtKB:Q8N5J4] xref: EMBL:AF518404 xref: EMBL:BC032317 xref: HGNC:HGNC:29549 xref: UniGene:Hs.577097 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057475 ! SPIC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020017 name: NCKIPSD_human def: "SH3 adapter protein SPIN90 gene" [UniProtKB:Q9NZQ3] synonym: "AF3P21" EXACT [UniProtKB:Q9NZQ3] synonym: "SPIN90" EXACT [UniProtKB:Q9NZQ3] xref: EMBL:AB069981 xref: EMBL:AB069982 xref: EMBL:AF178432 xref: EMBL:AF303581 xref: EMBL:AJ242655 xref: EMBL:BC016052 xref: HGNC:HGNC:15486 xref: UniGene:Hs.655006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059010 ! SPN90_HUMAN relationship: codes_for CCO:B0062829 ! Q6GU34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020018 name: SPARC_human def: "SPARC precursor gene" [UniProtKB:P09486] synonym: "ON" EXACT [UniProtKB:P09486] xref: EMBL:BC004974 xref: EMBL:BC008011 xref: EMBL:BC072457 xref: EMBL:J03040 xref: EMBL:M25738 xref: EMBL:M25739 xref: EMBL:M25740 xref: EMBL:M25741 xref: EMBL:M25742 xref: EMBL:M25743 xref: EMBL:M25744 xref: EMBL:M25745 xref: EMBL:M25746 xref: EMBL:Y00755 xref: HGNC:HGNC:11219 xref: UniGene:Hs.111779 xref: UniGene:Hs.653721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054944 ! SPRC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020019 name: SPRED1_human def: "Sprouty-related, EVH1 domain-containing protein 1 gene" [UniProtKB:Q7Z699] xref: EMBL:AC069381 xref: EMBL:AK091222 xref: EMBL:AY299089 xref: EMBL:BC018015 xref: HGNC:HGNC:20249 xref: UniGene:Hs.525781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054082 ! A8MWS2_HUMAN relationship: codes_for CCO:B0057195 ! SPRE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020020 name: SPRED2_human def: "Sprouty-related, EVH1 domain-containing protein 2 gene" [UniProtKB:Q7Z698] xref: EMBL:AY299090 xref: EMBL:BC111495 xref: HGNC:HGNC:17722 xref: UniGene:Hs.59332 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057194 ! SPRE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020021 name: SPRED3_human def: "Sprouty-related, EVH1 domain-containing protein 3 gene" [UniProtKB:Q2MJR0] xref: EMBL:DQ323928 xref: HGNC:HGNC:31041 xref: UniGene:Hs.448932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056215 ! SPRE3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020022 name: SUPT6H_human def: "Transcription elongation factor SPT6 gene" [UniProtKB:Q7KZ85] synonym: "KIAA0162" EXACT [UniProtKB:Q7KZ85] synonym: "SPT6H" EXACT [UniProtKB:Q7KZ85] xref: EMBL:AF070532 xref: EMBL:BC003692 xref: EMBL:BC003696 xref: EMBL:BC017105 xref: EMBL:BC033074 xref: EMBL:BC073963 xref: EMBL:D79984 xref: EMBL:U38623 xref: EMBL:U38658 xref: EMBL:U46691 xref: HGNC:HGNC:11470 xref: UniGene:Hs.250429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0014838 ! SPT6H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020023 name: SPTAN1_human def: "Spectrin alpha chain, brain gene" [UniProtKB:Q13813] synonym: "SPTA2" EXACT [UniProtKB:Q13813] xref: EMBL:AB191262 xref: EMBL:AB209860 xref: EMBL:AF148808 xref: EMBL:AL356481 xref: EMBL:BC053521 xref: EMBL:J05243 xref: EMBL:M18627 xref: EMBL:M24773 xref: EMBL:U26396 xref: EMBL:U83867 xref: EMBL:X86901 xref: HGNC:HGNC:11273 xref: UniGene:Hs.372331 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055944 ! SPTA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020024 name: SPTB_human def: "Spectrin beta chain, erythrocyte gene" [UniProtKB:P11277] synonym: "SPTB1" EXACT [UniProtKB:P11277] xref: EMBL:AL121774 xref: EMBL:J05500 xref: EMBL:M18054 xref: EMBL:M37884 xref: EMBL:M37885 xref: EMBL:M57948 xref: EMBL:X59510 xref: EMBL:X59511 xref: HGNC:HGNC:11274 xref: UniGene:Hs.417303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054990 ! SPTB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020025 name: SPTBN2_human def: "Spectrin beta chain, brain 2 gene" [UniProtKB:O15020] synonym: "KIAA0302" EXACT [UniProtKB:O15020] xref: EMBL:AB008567 xref: EMBL:AF026487 xref: EMBL:AF026488 xref: EMBL:AF079569 xref: HGNC:HGNC:11276 xref: UniGene:Hs.26915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054399 ! SPTN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020026 name: SPTBN4_human def: "Spectrin beta chain, brain 3 gene" [UniProtKB:Q9H254] synonym: "KIAA1642" EXACT [UniProtKB:Q9H254] synonym: "SPTBN3" EXACT [UniProtKB:Q9H254] xref: EMBL:AB046862 xref: EMBL:AF082075 xref: EMBL:AF311855 xref: EMBL:AY004226 xref: EMBL:AY004227 xref: HGNC:HGNC:14896 xref: UniGene:Hs.32706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058677 ! SPTN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020027 name: SPTBN5_human def: "Spectrin beta chain, brain 4 gene" [UniProtKB:Q9NRC6] synonym: "SPTBN4" EXACT [UniProtKB:Q9NRC6] xref: EMBL:AF233523 xref: HGNC:HGNC:15680 xref: UniGene:Hs.599221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058894 ! SPTN5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020028 name: SPRY1_human def: "Protein sprouty homolog 1 gene" [UniProtKB:O43609] xref: EMBL:AF041037 xref: EMBL:AY192146 xref: EMBL:AY590694 xref: EMBL:BC063856 xref: HGNC:HGNC:11269 xref: UniGene:Hs.436944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054499 ! SPY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020029 name: SPRY3_human def: "Protein sprouty homolog 3 gene" [UniProtKB:O43610] xref: EMBL:AF041038 xref: EMBL:AJ271735 xref: EMBL:BC069609 xref: EMBL:BC074972 xref: EMBL:BC074973 xref: HGNC:HGNC:11271 xref: UniGene:Hs.381912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054500 ! SPY3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020030 name: SPRY4_human def: "Protein sprouty homolog 4 gene" [UniProtKB:Q9C004] xref: EMBL:AF227516 xref: EMBL:AF227517 xref: EMBL:AK096464 xref: EMBL:AY538661 xref: EMBL:BC125096 xref: HGNC:HGNC:15533 xref: UniGene:Hs.323308 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053765 ! A4FVB3_HUMAN relationship: codes_for CCO:B0058614 ! SPY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020031 name: SPZ1_human def: "Spermatogenic leucine zipper protein 1 gene" [UniProtKB:Q9BXG8] synonym: "TSP1" EXACT [UniProtKB:Q9BXG8] xref: EMBL:AC026410 xref: EMBL:AF333098 xref: EMBL:AK098575 xref: EMBL:BC033798 xref: HGNC:HGNC:30721 xref: UniGene:Hs.519403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058553 ! SPZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020032 name: SQSTM1_human def: "Sequestosome-1 gene" [UniProtKB:Q13501] synonym: "ORCA" EXACT [UniProtKB:Q13501] synonym: "OSIL" EXACT [UniProtKB:Q13501] xref: EMBL:AF060494 xref: EMBL:BC000951 xref: EMBL:BC001874 xref: EMBL:BC003139 xref: EMBL:BC017222 xref: EMBL:BC019111 xref: EMBL:U41806 xref: EMBL:U46751 xref: HGNC:HGNC:11280 xref: UniGene:Hs.437277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055918 ! SQSTM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020033 name: SRA1_human def: "Steroid receptor RNA activator 1 gene" [UniProtKB:Q9HD15] synonym: "PP7684" EXACT [UniProtKB:Q9HD15] xref: EMBL:AF092038 xref: EMBL:AF293024 xref: EMBL:AF293025 xref: EMBL:AF293026 xref: EMBL:AF318361 xref: EMBL:BC040043 xref: EMBL:BC067895 xref: HGNC:HGNC:11281 xref: UniGene:Hs.655927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058823 ! SRA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020034 name: SRCAP_human def: "Helicase SRCAP gene" [UniProtKB:Q6ZRS2] synonym: "KIAA0309" EXACT [UniProtKB:Q6ZRS2] xref: EMBL:AB002307 xref: EMBL:AF143946 xref: EMBL:AK128030 xref: EMBL:BC052963 xref: HGNC:HGNC:16974 xref: UniGene:Hs.647334 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057042 ! SRCAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020035 name: SRFBP1_human def: "Serum response factor-binding protein 1 gene" [UniProtKB:Q8NEF9] xref: EMBL:AK058015 xref: EMBL:AY611630 xref: EMBL:BC017102 xref: EMBL:BC031222 xref: EMBL:CH471086 xref: HGNC:HGNC:26333 xref: UniGene:Hs.107622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057590 ! SRFB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020036 name: SERGEF_human def: "Secretion-regulating guanine nucleotide exchange factor gene" [UniProtKB:Q9UGK8] synonym: "DELGEF" EXACT [UniProtKB:Q9UGK8] synonym: "GNEFR" EXACT [UniProtKB:Q9UGK8] xref: EMBL:AJ243950 xref: EMBL:AJ243951 xref: EMBL:BC065375 xref: HGNC:HGNC:17499 xref: UniGene:Hs.32470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059123 ! SRGEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020037 name: SRGAP1_human def: "SLIT-ROBO Rho GTPase-activating protein 1 gene" [UniProtKB:Q7Z6B7] synonym: "ARHGAP13" EXACT [UniProtKB:Q7Z6B7] synonym: "KIAA1304" EXACT [UniProtKB:Q7Z6B7] xref: EMBL:AB037725 xref: EMBL:AK023899 xref: EMBL:BC053903 xref: HGNC:HGNC:17382 xref: UniGene:Hs.450763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057196 ! SRGP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020038 name: SRGAP3_human def: "SLIT-ROBO Rho GTPase-activating protein 3 gene" [UniProtKB:O43295] synonym: "ARHGAP14" EXACT [UniProtKB:O43295] synonym: "KIAA0411" EXACT [UniProtKB:O43295] synonym: "KIAA1156" EXACT [UniProtKB:O43295] synonym: "MEGAP" EXACT [UniProtKB:O43295] synonym: "SRGAP2" EXACT [UniProtKB:O43295] xref: EMBL:AB007871 xref: EMBL:AF427144 xref: EMBL:AF464189 xref: HGNC:HGNC:19744 xref: UniGene:Hs.654743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054466 ! SRGP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020039 name: SRP14_human def: "Signal recognition particle 14 kDa protein gene" [UniProtKB:P37108] xref: EMBL:BC035495 xref: EMBL:BC071716 xref: EMBL:BC100031 xref: EMBL:U07857 xref: EMBL:X73459 xref: HGNC:HGNC:11299 xref: UniGene:Hs.533732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055316 ! SRP14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020040 name: SERTAD2_human def: "SERTA domain-containing protein 2 gene" [UniProtKB:Q14140] synonym: "KIAA0127" EXACT [UniProtKB:Q14140] xref: EMBL:AC007365 xref: EMBL:BC074788 xref: EMBL:BC074789 xref: EMBL:BC101639 xref: EMBL:BC101641 xref: EMBL:D50917 xref: HGNC:HGNC:30784 xref: UniGene:Hs.693696 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055961 ! SRTD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020041 name: SERTAD3_human def: "SERTA domain-containing protein 3 gene" [UniProtKB:Q9UJW9] synonym: "RBT1" EXACT [UniProtKB:Q9UJW9] xref: EMBL:AF192529 xref: EMBL:AK074604 xref: EMBL:BC014061 xref: EMBL:BC050643 xref: EMBL:CH471126 xref: HGNC:HGNC:17931 xref: UniGene:Hs.515412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059180 ! SRTD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020042 name: SSBP2_human def: "Single-stranded DNA-binding protein 2 gene" [UniProtKB:P81877] synonym: "SSDP2" EXACT [UniProtKB:P81877] xref: EMBL:AF077048 xref: EMBL:AK074537 xref: EMBL:AL080076 xref: EMBL:AY026259 xref: EMBL:AY026260 xref: EMBL:AY026261 xref: EMBL:AY026262 xref: EMBL:AY026263 xref: EMBL:AY026264 xref: EMBL:AY026265 xref: EMBL:AY026266 xref: EMBL:AY026267 xref: EMBL:AY026268 xref: EMBL:AY026269 xref: EMBL:AY026270 xref: EMBL:AY026271 xref: EMBL:AY026272 xref: EMBL:AY026273 xref: EMBL:AY026274 xref: EMBL:AY026275 xref: EMBL:BC017020 xref: HGNC:HGNC:15831 xref: UniGene:Hs.699214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055656 ! SSBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020043 name: SSBP3_human def: "Single-stranded DNA-binding protein 3 gene" [UniProtKB:Q9BWW4] synonym: "SSDP" EXACT [UniProtKB:Q9BWW4] synonym: "SSDP1" EXACT [UniProtKB:Q9BWW4] xref: EMBL:AF500116 xref: EMBL:AY026293 xref: EMBL:AY026294 xref: EMBL:AY026295 xref: EMBL:AY026296 xref: EMBL:AY026297 xref: EMBL:AY026298 xref: EMBL:AY026299 xref: EMBL:AY026300 xref: EMBL:AY026301 xref: EMBL:AY026302 xref: EMBL:AY026303 xref: EMBL:AY026304 xref: EMBL:AY026305 xref: EMBL:AY026306 xref: EMBL:AY026307 xref: EMBL:AY026308 xref: EMBL:AY026309 xref: EMBL:AY026310 xref: EMBL:BC003605 xref: EMBL:BC066365 xref: HGNC:HGNC:15674 xref: UniGene:Hs.658676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058541 ! SSBP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020044 name: SSBP1_human def: "Single-stranded DNA-binding protein, mitochondrial precursor gene" [UniProtKB:Q04837] synonym: "SSBP" EXACT [UniProtKB:Q04837] xref: EMBL:AF277319 xref: EMBL:BC000895 xref: EMBL:M94556 xref: HGNC:HGNC:11317 xref: UniGene:Hs.490394 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055736 ! SSB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020045 name: SSX10_human def: "Protein SSX10 gene" [UniProtKB:A6NEJ1] xref: EMBL:AL606490 xref: HGNC:HGNC:34047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053808 ! SSX10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020046 name: SSX11_human def: "Protein SSX11 gene" [UniProtKB:A6NNU9] xref: EMBL:AL450023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053919 ! SSX11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020047 name: SSX1_human def: "Protein SSX1 gene" [UniProtKB:Q16384] xref: EMBL:AL683817 xref: EMBL:BC001003 xref: EMBL:BC125151 xref: EMBL:BC128611 xref: EMBL:S79325 xref: EMBL:X86174 xref: HGNC:HGNC:11335 xref: UniGene:Hs.434142 xref: UniGene:Hs.694472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056137 ! SSX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020048 name: SSX2_human def: "Protein SSX2 gene" [UniProtKB:Q16385] synonym: "SSX2A" EXACT [UniProtKB:Q16385] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056138 ! SSX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020049 name: SSX2B_human def: "Protein SSX2 gene" [UniProtKB:Q16385] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056138 ! SSX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020050 name: SSX3_human def: "Protein SSX3 gene" [UniProtKB:Q99909] xref: EMBL:AL606490 xref: EMBL:BC005904 xref: EMBL:BC103862 xref: EMBL:CH471164 xref: EMBL:S82471 xref: EMBL:U90840 xref: HGNC:HGNC:11337 xref: UniGene:Hs.558445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058460 ! SSX3_HUMAN relationship: codes_for CCO:B0058499 ! Q9BRW7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020051 name: SSX4_human def: "Protein SSX4 gene" [UniProtKB:O60224] synonym: "SSX4A" EXACT [UniProtKB:O60224] xref: EMBL:BC103864 xref: HGNC:HGNC:19655 xref: UniGene:Hs.558402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054532 ! SSX4_HUMAN relationship: codes_for CCO:B0056273 ! Q3SYD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020052 name: SSX4B_human def: "Protein SSX4 gene" [UniProtKB:O60224] xref: HGNC:HGNC:16880 xref: UniGene:Hs.558402 xref: UniGene:Hs.648298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054120 ! A8MYD4_HUMAN relationship: codes_for CCO:B0054532 ! SSX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020053 name: SSX5_human def: "Protein SSX5 gene" [UniProtKB:O60225] xref: EMBL:AL356464 xref: EMBL:AL683817 xref: EMBL:BC016640 xref: EMBL:U90842 xref: HGNC:HGNC:11339 xref: UniGene:Hs.166198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054533 ! SSX5_HUMAN relationship: codes_for CCO:B0056455 ! Q5JQ60_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020054 name: SSX6_human def: "Protein SSX6 gene" [UniProtKB:Q7RTT6] xref: EMBL:AL356464 xref: EMBL:BK000686 xref: EMBL:Z98304 xref: HGNC:HGNC:19652 xref: UniGene:Hs.511998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057131 ! SSX6_HUMAN relationship: codes_for CCO:B0058355 ! Q96QI0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020055 name: SSX7_human def: "Protein SSX7 gene" [UniProtKB:Q7RTT5] xref: EMBL:AL450023 xref: EMBL:BK000687 xref: HGNC:HGNC:19653 xref: UniGene:Hs.558712 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057130 ! SSX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020056 name: SSX8_human def: "Protein SSX8 gene" [UniProtKB:Q7RTT4] xref: EMBL:AL450023 xref: EMBL:BK000688 xref: HGNC:HGNC:19654 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057129 ! SSX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020057 name: SSX9_human def: "Protein SSX9 gene" [UniProtKB:Q7RTT3] xref: EMBL:AL606490 xref: EMBL:BK000689 xref: HGNC:HGNC:19655 xref: UniGene:Hs.553667 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057128 ! SSX9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020058 name: ST18_human def: "Suppression of tumorigenicity protein 18 gene" [UniProtKB:O60284] synonym: "KIAA0535" EXACT [UniProtKB:O60284] synonym: "ZNF387" EXACT [UniProtKB:O60284] xref: EMBL:AB011107 xref: EMBL:BC117147 xref: EMBL:BC117149 xref: HGNC:HGNC:18695 xref: UniGene:Hs.655499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054540 ! ST18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020059 name: STAMBP_human def: "STAM-binding protein gene" [UniProtKB:O95630] synonym: "AMSH" EXACT [UniProtKB:O95630] xref: EMBL:AC073046 xref: EMBL:BC007682 xref: EMBL:BC065574 xref: EMBL:BC101467 xref: EMBL:BC101469 xref: EMBL:U73522 xref: HGNC:HGNC:16950 xref: UniGene:Hs.469018 xref: UniGene:Hs.657598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054776 ! STABP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020060 name: STAC2_human def: "SH3 and cysteine-rich domain-containing protein 2 gene" [UniProtKB:Q6ZMT1] xref: EMBL:AJ608762 xref: EMBL:AK131500 xref: EMBL:BC109231 xref: HGNC:HGNC:23990 xref: UniGene:Hs.145068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056992 ! STAC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020061 name: STAC3_human def: "SH3 and cysteine-rich domain-containing protein 3 gene" [UniProtKB:Q96MF2] xref: EMBL:AK057013 xref: EMBL:BC008069 xref: HGNC:HGNC:28423 xref: UniGene:Hs.417595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058288 ! STAC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020062 name: STAC_human def: "SH3 and cysteine-rich domain-containing protein gene" [UniProtKB:Q99469] xref: EMBL:D86640 xref: HGNC:HGNC:11353 xref: UniGene:Hs.56045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058415 ! STAC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020063 name: STAM_human def: "Signal transducing adapter molecule 1 gene" [UniProtKB:Q92783] synonym: "STAM1" EXACT [UniProtKB:Q92783] xref: EMBL:BC030586 xref: EMBL:U43899 xref: HGNC:HGNC:11357 xref: UniGene:Hs.441498 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058093 ! STAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020064 name: STAP1_human def: "Signal-transducing adaptor protein 1 gene" [UniProtKB:Q9ULZ2] synonym: "BRDG1" EXACT [UniProtKB:Q9ULZ2] xref: EMBL:AB023483 xref: EMBL:BC014958 xref: HGNC:HGNC:24133 xref: UniGene:Hs.435579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059239 ! STAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020065 name: STAT2_human def: "Signal transducer and activator of transcription 2 gene" [UniProtKB:P52630] xref: EMBL:AY525126 xref: EMBL:BC051284 xref: EMBL:M97934 xref: EMBL:S81491 xref: EMBL:U18671 xref: HGNC:HGNC:11363 xref: UniGene:Hs.530595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023422 ! STAT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020066 name: STAT4_human def: "Signal transducer and activator of transcription 4 gene" [UniProtKB:Q14765] xref: EMBL:AF423072 xref: EMBL:BC031212 xref: EMBL:L78440 xref: HGNC:HGNC:11365 xref: UniGene:Hs.80642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023418 ! STAT4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020067 name: STC1_human def: "Stanniocalcin-1 precursor gene" [UniProtKB:P52823] synonym: "STC" EXACT [UniProtKB:P52823] xref: EMBL:AF242179 xref: EMBL:BC029044 xref: EMBL:U25997 xref: EMBL:U46768 xref: HGNC:HGNC:11373 xref: UniGene:Hs.25590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055502 ! STC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020068 name: NR5A1_human def: "Steroidogenic factor 1 gene" [UniProtKB:Q13285] synonym: "AD4BP" EXACT [UniProtKB:Q13285] synonym: "FTZF1" EXACT [UniProtKB:Q13285] synonym: "SF1" EXACT [UniProtKB:Q13285] xref: EMBL:AL137846 xref: EMBL:AL354979 xref: EMBL:BC032501 xref: EMBL:D88155 xref: EMBL:U32592 xref: EMBL:U76388 xref: HGNC:HGNC:7983 xref: UniGene:Hs.495108 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055892 ! STF1_HUMAN relationship: codes_for CCO:B0056588 ! Q5T6F6_HUMAN relationship: codes_for CCO:B0056589 ! Q5T6F7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020069 name: STIL_human def: "SCL-interrupting locus protein gene" [UniProtKB:Q15468] synonym: "SIL" EXACT [UniProtKB:Q15468] xref: EMBL:AF349642 xref: EMBL:AF349643 xref: EMBL:AF349644 xref: EMBL:AF349645 xref: EMBL:AF349646 xref: EMBL:AF349647 xref: EMBL:AF349648 xref: EMBL:AF349649 xref: EMBL:AF349650 xref: EMBL:AF349651 xref: EMBL:AF349652 xref: EMBL:AF349653 xref: EMBL:AF349654 xref: EMBL:AF349655 xref: EMBL:AF349656 xref: EMBL:AF349657 xref: EMBL:AL135960 xref: EMBL:AL513322 xref: EMBL:BC126223 xref: EMBL:CR749851 xref: EMBL:M74558 xref: HGNC:HGNC:10879 xref: UniGene:Hs.525198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056068 ! STIL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020070 name: STK3_human def: "Serine/threonine-protein kinase 3 gene" [UniProtKB:Q13188] synonym: "MST2" EXACT [UniProtKB:Q13188] xref: EMBL:AP002087 xref: EMBL:AP003355 xref: EMBL:AP003467 xref: EMBL:AP003551 xref: EMBL:BC010640 xref: EMBL:U26424 xref: EMBL:U60206 xref: EMBL:Z25422 xref: HGNC:HGNC:11406 xref: UniGene:Hs.492333 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055885 ! STK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020071 name: STOML3_human def: "Stomatin-like protein 3 gene" [UniProtKB:Q8TAV4] xref: EMBL:AL445590 xref: EMBL:BC025760 xref: HGNC:HGNC:19420 xref: UniGene:Hs.327794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057894 ! STML3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020072 name: STON1_human def: "Stonin-1 gene" [UniProtKB:Q9Y6Q2] synonym: "SALF" EXACT [UniProtKB:Q9Y6Q2] synonym: "SBLF" EXACT [UniProtKB:Q9Y6Q2] synonym: "STN1" EXACT [UniProtKB:Q9Y6Q2] xref: EMBL:AF026169 xref: EMBL:AF255310 xref: EMBL:AY026319 xref: HGNC:HGNC:17003 xref: UniGene:Hs.44385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059412 ! STON1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020073 name: STON2_human def: "Stonin-2 gene" [UniProtKB:Q8WXE9] synonym: "STN2" EXACT [UniProtKB:Q8WXE9] synonym: "STNB" EXACT [UniProtKB:Q8WXE9] xref: EMBL:AF255309 xref: EMBL:AF380833 xref: EMBL:AF449430 xref: EMBL:AL121769 xref: EMBL:AL136040 xref: EMBL:BC069389 xref: EMBL:BC117493 xref: HGNC:HGNC:30652 xref: UniGene:Hs.14248 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058016 ! STON2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020074 name: TNP1_human def: "Spermatid nuclear transition protein 1 gene" [UniProtKB:P09430] xref: EMBL:BC029516 xref: EMBL:M59924 xref: EMBL:X07948 xref: HGNC:HGNC:11951 xref: UniGene:Hs.3017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054943 ! STP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020075 name: STRADB_human def: "STE20-related kinase adapter protein beta gene" [UniProtKB:Q9C0K7] synonym: "ALS2CR2" EXACT [UniProtKB:Q9C0K7] synonym: "ILPIP" EXACT [UniProtKB:Q9C0K7] synonym: "PRO1038" EXACT [UniProtKB:Q9C0K7] xref: EMBL:AB038950 xref: EMBL:AC007282 xref: EMBL:AF116618 xref: EMBL:AK027637 xref: EMBL:AY093697 xref: EMBL:BC008302 xref: EMBL:BC090871 xref: HGNC:HGNC:13205 xref: UniGene:Hs.652338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0002119 ! STRAB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020076 name: STUB1_human def: "STIP1 homology and U box-containing protein 1 gene" [UniProtKB:Q9UNE7] synonym: "CHIP" EXACT [UniProtKB:Q9UNE7] synonym: "PP1131" EXACT [UniProtKB:Q9UNE7] xref: EMBL:AE006464 xref: EMBL:AF039689 xref: EMBL:AF129085 xref: EMBL:AF217968 xref: EMBL:AF432221 xref: EMBL:BC007545 xref: EMBL:BC017178 xref: EMBL:BC022788 xref: EMBL:BC063617 xref: HGNC:HGNC:11427 xref: UniGene:Hs.592081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059251 ! STUB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020077 name: STX12_human def: "Syntaxin-12 gene" [UniProtKB:Q86Y82] xref: EMBL:AF123769 xref: EMBL:AL035306 xref: EMBL:BC046999 xref: HGNC:HGNC:11430 xref: UniGene:Hs.523855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057301 ! STX12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020078 name: STX1A_human def: "Syntaxin-1A gene" [UniProtKB:Q16623] synonym: "STX1" EXACT [UniProtKB:Q16623] xref: EMBL:AF297001 xref: EMBL:AF297002 xref: EMBL:AF297003 xref: EMBL:BC000444 xref: EMBL:BC003011 xref: EMBL:BC064644 xref: EMBL:D37932 xref: EMBL:L37792 xref: EMBL:U12918 xref: EMBL:U87310 xref: EMBL:U87314 xref: EMBL:U87315 xref: HGNC:HGNC:11433 xref: UniGene:Hs.647024 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056163 ! STX1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020079 name: STX2_human def: "Syntaxin-2 gene" [UniProtKB:P32856] synonym: "EPIM" EXACT [UniProtKB:P32856] synonym: "STX2A" EXACT [UniProtKB:P32856] synonym: "STX2B" EXACT [UniProtKB:P32856] synonym: "STX2C" EXACT [UniProtKB:P32856] xref: EMBL:BC047496 xref: EMBL:D14582 xref: HGNC:HGNC:3403 xref: UniGene:Hs.437585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055261 ! STX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020080 name: STYXL1_human def: "Serine/threonine/tyrosine-interacting-like protein 1 gene" [UniProtKB:Q9Y6J8] synonym: "DUSP24" EXACT [UniProtKB:Q9Y6J8] synonym: "MKSTYX" EXACT [UniProtKB:Q9Y6J8] xref: EMBL:AC006330 xref: EMBL:AF069762 xref: EMBL:AF169647 xref: EMBL:AF169648 xref: EMBL:AF188201 xref: EMBL:AF188202 xref: EMBL:AF188203 xref: EMBL:AF188204 xref: EMBL:BC024035 xref: HGNC:HGNC:18165 xref: UniGene:Hs.11615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059409 ! STYL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020081 name: RBPJ_human def: "Recombining binding protein suppressor of hairless gene" [UniProtKB:Q06330] synonym: "IGKJRB" EXACT [UniProtKB:Q06330] synonym: "IGKJRB1" EXACT [UniProtKB:Q06330] synonym: "RBPJK" EXACT [UniProtKB:Q06330] synonym: "RBPSUH" EXACT [UniProtKB:Q06330] xref: EMBL:BC020780 xref: EMBL:BC053531 xref: EMBL:BC064976 xref: EMBL:L07872 xref: EMBL:L07874 xref: EMBL:L07875 xref: EMBL:L07876 xref: HGNC:HGNC:5724 xref: UniGene:Hs.479396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055767 ! SUH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020082 name: SUZ12_human def: "Polycomb protein SUZ12 gene" [UniProtKB:Q15022] synonym: "CHET9" EXACT [UniProtKB:Q15022] synonym: "JJAZ1" EXACT [UniProtKB:Q15022] synonym: "KIAA0160" EXACT [UniProtKB:Q15022] xref: EMBL:BC015704 xref: EMBL:D63881 xref: HGNC:HGNC:17101 xref: UniGene:Hs.462732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056036 ! SUZ12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020083 name: SVIL_human def: "Supervillin gene" [UniProtKB:O95425] xref: EMBL:AF051850 xref: EMBL:AF051851 xref: EMBL:AF109135 xref: EMBL:AL158167 xref: EMBL:AL160060 xref: HGNC:HGNC:11480 xref: UniGene:Hs.499209 xref: UniGene:Hs.697793 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054762 ! SVIL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020084 name: SYDE1_human def: "Rho GTPase-activating protein SYDE1 gene" [UniProtKB:Q6ZW31] xref: EMBL:AK023573 xref: EMBL:AK123686 xref: EMBL:BC018942 xref: EMBL:BC029926 xref: EMBL:CH471106 xref: HGNC:HGNC:25824 xref: UniGene:Hs.528701 xref: UniGene:Hs.701386 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057088 ! SYDE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020085 name: SYDE2_human def: "Rho GTPase-activating protein SYDE2 gene" [UniProtKB:Q5VT97] xref: EMBL:AK023877 xref: EMBL:AL603750 xref: EMBL:AL834286 xref: HGNC:HGNC:25841 xref: UniGene:Hs.670497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056649 ! SYDE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020086 name: SYNJ2BP_human def: "Synaptojanin-2-binding protein gene" [UniProtKB:P57105] synonym: "OMP25" EXACT [UniProtKB:P57105] xref: EMBL:AK002133 xref: EMBL:AY534623 xref: EMBL:BC007704 xref: EMBL:CH471061 xref: HGNC:HGNC:18955 xref: UniGene:Hs.443661 xref: UniGene:Hs.704691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055558 ! SYJ2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020087 name: TSC22D1_human def: "TSC22 domain family protein 1 gene" [UniProtKB:Q15714] synonym: "hucep-2" EXACT [UniProtKB:Q15714] synonym: "KIAA1994" EXACT [UniProtKB:Q15714] synonym: "TGFB1I4" EXACT [UniProtKB:Q15714] synonym: "TSC22" EXACT [UniProtKB:Q15714] xref: EMBL:AB082525 xref: EMBL:AF256226 xref: EMBL:AJ222700 xref: EMBL:AK312345 xref: EMBL:AL138960 xref: EMBL:AL139184 xref: EMBL:BC000456 xref: EMBL:BC016867 xref: EMBL:BC069207 xref: EMBL:BC105277 xref: EMBL:BC146664 xref: EMBL:BC146679 xref: EMBL:CH471075 xref: EMBL:CR456711 xref: EMBL:CR627459 xref: EMBL:D38585 xref: EMBL:D87061 xref: EMBL:U35048 xref: HGNC:HGNC:16826 xref: UniGene:Hs.507916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056098 ! T22D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020088 name: TSC22D2_human def: "TSC22 domain family protein 2 gene" [UniProtKB:O75157] synonym: "KIAA0669" EXACT [UniProtKB:O75157] synonym: "TILZ4" EXACT [UniProtKB:O75157] xref: EMBL:AB014569 xref: EMBL:AF201290 xref: EMBL:AF201291 xref: EMBL:AF201292 xref: EMBL:BC044643 xref: HGNC:HGNC:29095 xref: UniGene:Hs.644065 xref: UniGene:Hs.665220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054607 ! T22D2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020089 name: TSC22D3_human def: "TSC22 domain family protein 3 gene" [UniProtKB:Q99576] synonym: "DSIPI" EXACT [UniProtKB:Q99576] synonym: "GILZ" EXACT [UniProtKB:Q99576] xref: EMBL:AB025432 xref: EMBL:AF153603 xref: EMBL:AF183393 xref: EMBL:AF228339 xref: EMBL:AK092645 xref: EMBL:AK092669 xref: EMBL:AL110191 xref: EMBL:AL590423 xref: EMBL:BC018148 xref: EMBL:BC072446 xref: EMBL:CH471120 xref: EMBL:CR533450 xref: EMBL:CR933650 xref: EMBL:Z50781 xref: HGNC:HGNC:3051 xref: UniGene:Hs.522074 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056465 ! Q5JRI9_HUMAN relationship: codes_for CCO:B0056466 ! Q5JRJ0_HUMAN relationship: codes_for CCO:B0056467 ! Q5JRJ1_HUMAN relationship: codes_for CCO:B0056468 ! Q5JRJ2_HUMAN relationship: codes_for CCO:B0058425 ! T22D3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020090 name: GTF2E1_human def: "General transcription factor IIE subunit 1 gene" [UniProtKB:P29083] synonym: "TF2E1" EXACT [UniProtKB:P29083] xref: EMBL:S67859 xref: EMBL:X63468 xref: HGNC:HGNC:4650 xref: UniGene:Hs.445272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055208 ! T2EA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020091 name: GTF2E2_human def: "Transcription initiation factor IIE subunit beta gene" [UniProtKB:P29084] synonym: "TF2E2" EXACT [UniProtKB:P29084] xref: EMBL:AF292056 xref: EMBL:AF292057 xref: EMBL:AF292058 xref: EMBL:AF292059 xref: EMBL:AF292060 xref: EMBL:AF292061 xref: EMBL:AF292062 xref: EMBL:BC030572 xref: EMBL:S67861 xref: EMBL:X63469 xref: HGNC:HGNC:4651 xref: UniGene:Hs.77100 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055209 ! T2EB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020092 name: GTF2F2_human def: "General transcription factor IIF subunit 2 gene" [UniProtKB:P13984] synonym: "RAP30" EXACT [UniProtKB:P13984] xref: EMBL:AK291545 xref: EMBL:AL138693 xref: EMBL:AL138963 xref: EMBL:BC001771 xref: EMBL:BT019525 xref: EMBL:CH471075 xref: EMBL:X16901 xref: EMBL:X59745 xref: HGNC:HGNC:4653 xref: UniGene:Hs.654582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020975 ! T2FB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020093 name: TAS2R10_human def: "Taste receptor type 2 member 10 gene" [UniProtKB:Q9NYW0] xref: EMBL:AF227136 xref: EMBL:AY724946 xref: EMBL:BC069089 xref: EMBL:BC101762 xref: EMBL:BC101764 xref: HGNC:HGNC:14918 xref: UniGene:Hs.533756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058978 ! T2R10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020094 name: TAS2R12_human def: "Putative Taste receptor type 2 member 12 gene" [UniProtKB:P59531] synonym: "TAS2R26" EXACT [UniProtKB:P59531] xref: HGNC:HGNC:19103 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055576 ! T2R12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020095 name: TAS2R13_human def: "Taste receptor type 2 member 13 gene" [UniProtKB:Q9NYV9] xref: EMBL:AF227137 xref: EMBL:AY724945 xref: EMBL:BC069376 xref: EMBL:BC095518 xref: HGNC:HGNC:14919 xref: UniGene:Hs.679407 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058977 ! T2R13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020096 name: TAS2R14_human def: "Taste receptor type 2 member 14 gene" [UniProtKB:Q9NYV8] xref: EMBL:AF227138 xref: EMBL:AY724944 xref: EMBL:BC069148 xref: EMBL:BC101993 xref: EMBL:BC101994 xref: EMBL:BC103699 xref: HGNC:HGNC:14920 xref: UniGene:Hs.408153 xref: UniGene:Hs.679406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058976 ! T2R14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020097 name: TAS2R16_human def: "Taste receptor type 2 member 16 gene" [UniProtKB:Q9NYV7] xref: EMBL:AC004838 xref: EMBL:AF227139 xref: EMBL:AY724962 xref: EMBL:BC095524 xref: HGNC:HGNC:14921 xref: UniGene:Hs.272395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058975 ! T2R16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020098 name: TAS2R38_human def: "Taste receptor type 2 member 38 gene" [UniProtKB:P59533] synonym: "PTC" EXACT [UniProtKB:P59533] xref: EMBL:AF494231 xref: EMBL:AY114095 xref: EMBL:AY258598 xref: EMBL:AY724960 xref: EMBL:BC104933 xref: EMBL:BC104937 xref: HGNC:HGNC:9584 xref: UniGene:Hs.647085 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055577 ! T2R38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020099 name: TAS2R39_human def: "Taste receptor type 2 member 39 gene" [UniProtKB:P59534] xref: EMBL:AF494230 xref: EMBL:AY724959 xref: EMBL:BC100947 xref: EMBL:BC100948 xref: HGNC:HGNC:18886 xref: UniGene:Hs.553660 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055578 ! T2R39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020100 name: TAS2R41_human def: "Taste receptor type 2 member 41 gene" [UniProtKB:P59536] xref: EMBL:AF494232 xref: EMBL:AY114093 xref: EMBL:AY724956 xref: EMBL:BC101157 xref: EMBL:BC101158 xref: HGNC:HGNC:18883 xref: UniGene:Hs.650648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055579 ! T2R41_HUMAN relationship: codes_for CCO:B0056294 ! Q495I2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020101 name: TAS2R42_human def: "Taste receptor type 2 member 42 gene" [UniProtKB:Q7RTR8] synonym: "TAS2R55" EXACT [UniProtKB:Q7RTR8] xref: EMBL:AC010176 xref: EMBL:AY724953 xref: EMBL:BK001099 xref: HGNC:HGNC:18888 xref: UniGene:Hs.553716 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057125 ! T2R42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020102 name: TAS2R43_human def: "Taste receptor type 2 member 43 gene" [UniProtKB:P59537] xref: EMBL:AF494237 xref: EMBL:AY114089 xref: EMBL:AY724943 xref: EMBL:BC117423 xref: HGNC:HGNC:18875 xref: UniGene:Hs.688195 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055580 ! T2R43_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020103 name: TAS2R44_human def: "Taste receptor type 2 member 44 gene" [UniProtKB:P59538] xref: EMBL:AF494228 xref: EMBL:AY114090 xref: EMBL:AY724942 xref: EMBL:BC117421 xref: HGNC:HGNC:18881 xref: UniGene:Hs.688197 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055581 ! T2R44_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020104 name: TAS2R45_human def: "Taste receptor type 2 member 45 gene" [UniProtKB:P59539] synonym: "GPR59" EXACT [UniProtKB:P59539] xref: EMBL:AF494226 xref: HGNC:HGNC:18876 xref: UniGene:Hs.287378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055582 ! T2R45_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020105 name: TAS2R46_human def: "Taste receptor type 2 member 46 gene" [UniProtKB:P59540] xref: EMBL:AF494227 xref: EMBL:AY114091 xref: EMBL:AY724941 xref: HGNC:HGNC:18877 xref: UniGene:Hs.688193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055583 ! T2R46_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020106 name: TAS2R47_human def: "Taste receptor type 2 member 47 gene" [UniProtKB:P59541] xref: EMBL:AF494233 xref: EMBL:AY724940 xref: HGNC:HGNC:18878 xref: UniGene:Hs.679464 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055584 ! T2R47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020107 name: TAS2R48_human def: "Taste receptor type 2 member 48 gene" [UniProtKB:P59542] xref: EMBL:AF494234 xref: EMBL:AY724939 xref: EMBL:BC101804 xref: EMBL:BC111998 xref: HGNC:HGNC:18879 xref: UniGene:Hs.687025 xref: UniGene:Hs.688196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055585 ! T2R48_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020108 name: TAS2R49_human def: "Taste receptor type 2 member 49 gene" [UniProtKB:P59543] xref: EMBL:AF494236 xref: EMBL:AY114092 xref: EMBL:AY724938 xref: EMBL:BC100915 xref: EMBL:BC100916 xref: EMBL:BC100918 xref: HGNC:HGNC:18880 xref: UniGene:Hs.686384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055586 ! T2R49_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020109 name: TAS2R50_human def: "Taste receptor type 2 member 50 gene" [UniProtKB:P59544] xref: EMBL:AF494235 xref: EMBL:AY114088 xref: EMBL:AY724937 xref: EMBL:BC112100 xref: HGNC:HGNC:18882 xref: UniGene:Hs.688194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055587 ! T2R50_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020110 name: TAS2R60_human def: "Taste receptor type 2 member 60 gene" [UniProtKB:P59551] xref: EMBL:AY114094 xref: EMBL:AY724955 xref: EMBL:BC100938 xref: EMBL:BC100939 xref: EMBL:BC100940 xref: EMBL:BK001100 xref: HGNC:HGNC:20639 xref: UniGene:Hs.688222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055588 ! T2R60_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020111 name: TM4SF4_human def: "Transmembrane 4 L6 family member 4 gene" [UniProtKB:P48230] synonym: "ILTMP" EXACT [UniProtKB:P48230] xref: EMBL:BC001386 xref: EMBL:BT007430 xref: EMBL:U31449 xref: HGNC:HGNC:11856 xref: UniGene:Hs.133527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055400 ! T4S4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020112 name: TP53TG5_human def: "TP53-target gene 5 protein gene" [UniProtKB:Q9Y2B4] synonym: "C20orf10" EXACT [UniProtKB:Q9Y2B4] xref: EMBL:AB017802 xref: EMBL:AL021578 xref: EMBL:BC036785 xref: HGNC:HGNC:15856 xref: UniGene:Hs.401982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059299 ! T53G5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020113 name: TAS2R1_human def: "Taste receptor type 2 member 1 gene" [UniProtKB:Q9NYW7] xref: EMBL:AF227129 xref: EMBL:AY724812 xref: EMBL:BC101729 xref: EMBL:BC101731 xref: HGNC:HGNC:14909 xref: UniGene:Hs.567492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058984 ! TA2R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020114 name: TAS2R3_human def: "Taste receptor type 2 member 3 gene" [UniProtKB:Q9NYW6] xref: EMBL:AC004979 xref: EMBL:AF227130 xref: EMBL:AY724961 xref: EMBL:BC069337 xref: EMBL:BC095523 xref: HGNC:HGNC:14910 xref: UniGene:Hs.676011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058983 ! TA2R3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020115 name: TAS2R4_human def: "Taste receptor type 2 member 4 gene" [UniProtKB:Q9NYW5] xref: EMBL:AC004979 xref: EMBL:AF227131 xref: EMBL:AY724958 xref: HGNC:HGNC:14911 xref: UniGene:Hs.669863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058982 ! TA2R4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020116 name: TAS2R7_human def: "Taste receptor type 2 member 7 gene" [UniProtKB:Q9NYW3] xref: EMBL:AF227133 xref: EMBL:AY724936 xref: EMBL:BC069091 xref: EMBL:BC093992 xref: EMBL:BC113561 xref: HGNC:HGNC:14913 xref: UniGene:Hs.533754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058981 ! TA2R7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020117 name: TAS2R8_human def: "Taste receptor type 2 member 8 gene" [UniProtKB:Q9NYW2] xref: EMBL:AF227134 xref: EMBL:AY724935 xref: EMBL:BC069084 xref: EMBL:BC069551 xref: EMBL:BC096701 xref: EMBL:BC096735 xref: EMBL:BC098353 xref: HGNC:HGNC:14915 xref: UniGene:Hs.533755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058980 ! TA2R8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020118 name: TAS2R9_human def: "Taste receptor type 2 member 9 gene" [UniProtKB:Q9NYW1] xref: EMBL:AB199063 xref: EMBL:AB199064 xref: EMBL:AB199065 xref: EMBL:AF227135 xref: EMBL:AY724954 xref: EMBL:BC069066 xref: EMBL:BC095519 xref: HGNC:HGNC:14917 xref: UniGene:Hs.272391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058979 ! TA2R9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020119 name: TBXA2R_human def: "Thromboxane A2 receptor gene" [UniProtKB:P21731] xref: EMBL:AC005175 xref: EMBL:AY429110 xref: EMBL:BC074749 xref: EMBL:BC074750 xref: EMBL:BC121148 xref: EMBL:D15056 xref: EMBL:D38081 xref: EMBL:DQ268653 xref: EMBL:U11271 xref: EMBL:U27325 xref: HGNC:HGNC:11608 xref: UniGene:Hs.442530 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055138 ! TA2R_HUMAN relationship: codes_for CCO:B0055819 ! Q0VAB0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020120 name: TAAR1_human def: "Trace amine-associated receptor 1 gene" [UniProtKB:Q96RJ0] synonym: "TA1" EXACT [UniProtKB:Q96RJ0] synonym: "TAR1" EXACT [UniProtKB:Q96RJ0] synonym: "TRAR1" EXACT [UniProtKB:Q96RJ0] xref: EMBL:AF200627 xref: EMBL:AF380185 xref: EMBL:AL513524 xref: EMBL:AY180374 xref: EMBL:BC101825 xref: EMBL:BC112194 xref: HGNC:HGNC:17734 xref: UniGene:Hs.375030 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058379 ! TAAR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020121 name: TAAR2_human def: "Trace amine-associated receptor 2 gene" [UniProtKB:Q9P1P5] synonym: "GPR58" EXACT [UniProtKB:Q9P1P5] xref: EMBL:AF112460 xref: EMBL:AL513524 xref: EMBL:AY702304 xref: EMBL:AY703480 xref: EMBL:BC067461 xref: EMBL:BC067462 xref: EMBL:BC067463 xref: HGNC:HGNC:4514 xref: UniGene:Hs.272382 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059039 ! TAAR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020122 name: TAAR3_human def: "Putative trace amine-associated receptor 3 gene" [UniProtKB:Q9P1P4] synonym: "GPR57" EXACT [UniProtKB:Q9P1P4] xref: EMBL:AF112461 xref: HGNC:HGNC:4513 xref: UniGene:Hs.679662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059038 ! TAAR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020123 name: TAAR5_human def: "Trace amine-associated receptor 5 gene" [UniProtKB:O14804] synonym: "PNR" EXACT [UniProtKB:O14804] xref: EMBL:AF021818 xref: EMBL:AL513524 xref: EMBL:AY702306 xref: EMBL:BC069171 xref: EMBL:BC095541 xref: EMBL:BC112209 xref: EMBL:BC112211 xref: HGNC:HGNC:30236 xref: UniGene:Hs.248198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054073 ! A8MW54_HUMAN relationship: codes_for CCO:B0054378 ! TAAR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020124 name: TAAR6_human def: "Trace amine-associated receptor 6 gene" [UniProtKB:Q96RI8] synonym: "TA4" EXACT [UniProtKB:Q96RI8] synonym: "TAR4" EXACT [UniProtKB:Q96RI8] synonym: "TRAR4" EXACT [UniProtKB:Q96RI8] xref: EMBL:AF380192 xref: EMBL:AL513524 xref: EMBL:AY183470 xref: EMBL:BC069157 xref: HGNC:HGNC:20978 xref: UniGene:Hs.434196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058377 ! TAAR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020125 name: TAAR8_human def: "Trace amine-associated receptor 8 gene" [UniProtKB:Q969N4] synonym: "GPR102" EXACT [UniProtKB:Q969N4] synonym: "TA5" EXACT [UniProtKB:Q969N4] synonym: "TAR5" EXACT [UniProtKB:Q969N4] synonym: "TRAR5" EXACT [UniProtKB:Q969N4] xref: EMBL:AF380193 xref: EMBL:AF411116 xref: EMBL:AL513524 xref: EMBL:AY183468 xref: EMBL:BC069166 xref: HGNC:HGNC:14964 xref: UniGene:Hs.350571 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058135 ! TAAR8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020126 name: TAAR9_human def: "Trace amine-associated receptor 9 gene" [UniProtKB:Q96RI9] synonym: "TA3" EXACT [UniProtKB:Q96RI9] synonym: "TAR3" EXACT [UniProtKB:Q96RI9] synonym: "TRAR3" EXACT [UniProtKB:Q96RI9] xref: EMBL:AF380189 xref: EMBL:AY183469 xref: HGNC:HGNC:20977 xref: UniGene:Hs.434116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058378 ! TAAR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020127 name: TACSTD2_human def: "Tumor-associated calcium signal transducer 2 precursor gene" [UniProtKB:P09758] synonym: "GA733-1" EXACT [UniProtKB:P09758] synonym: "M1S1" EXACT [UniProtKB:P09758] synonym: "TROP2" EXACT [UniProtKB:P09758] xref: EMBL:BC009409 xref: EMBL:J04152 xref: EMBL:X13425 xref: EMBL:X77753 xref: EMBL:X77754 xref: HGNC:HGNC:11530 xref: UniGene:Hs.23582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054950 ! TACD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020128 name: TADA1L_human def: "Transcriptional adapter 1-like protein gene" [UniProtKB:Q96BN2] xref: EMBL:AK291922 xref: EMBL:AL008639 xref: EMBL:AL009182 xref: EMBL:BC015401 xref: EMBL:CH471067 xref: HGNC:HGNC:30631 xref: UniGene:Hs.435967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058167 ! TAD1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020129 name: TADA2B_human def: "Transcriptional adapter 2-beta gene" [UniProtKB:Q86TJ2] synonym: "ADA2B" EXACT [UniProtKB:Q86TJ2] xref: EMBL:AC097382 xref: EMBL:BC047794 xref: EMBL:BC101334 xref: EMBL:BC101335 xref: EMBL:BC101336 xref: EMBL:BC101337 xref: EMBL:BX641147 xref: UniGene:Hs.518614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057239 ! TAD2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020130 name: TAF11_human def: "Transcription initiation factor TFIID subunit 11 gene" [UniProtKB:Q15544] synonym: "PRO2134" EXACT [UniProtKB:Q15544] synonym: "TAF2I" EXACT [UniProtKB:Q15544] xref: EMBL:AF118094 xref: EMBL:AL033520 xref: EMBL:AY217767 xref: EMBL:BC021972 xref: EMBL:BT019404 xref: EMBL:BT019405 xref: EMBL:CR542068 xref: EMBL:D63705 xref: EMBL:X83928 xref: HGNC:HGNC:11544 xref: UniGene:Hs.112444 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056072 ! TAF11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020131 name: TAF1A_human def: "TATA box-binding protein-associated factor RNA polymerase I subunit A gene" [UniProtKB:Q15573] xref: EMBL:AK001054 xref: EMBL:AL592148 xref: EMBL:BC013808 xref: EMBL:L39060 xref: HGNC:HGNC:11532 xref: UniGene:Hs.153088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056075 ! TAF1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020132 name: TAF1B_human def: "TATA box-binding protein-associated factor RNA polymerase I subunit B gene" [UniProtKB:Q53T94] xref: EMBL:AC010969 xref: EMBL:BC018137 xref: EMBL:L39061 xref: HGNC:HGNC:11533 xref: UniGene:Hs.654508 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056366 ! TAF1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020133 name: TAF2_human def: "Transcription initiation factor TFIID subunit 2 gene" [UniProtKB:Q6P1X5] synonym: "CIF150" EXACT [UniProtKB:Q6P1X5] synonym: "TAF2B" EXACT [UniProtKB:Q6P1X5] xref: EMBL:AC021945 xref: EMBL:AC107960 xref: EMBL:AF026445 xref: EMBL:AF040701 xref: EMBL:AF057694 xref: EMBL:BC035673 xref: EMBL:BC047732 xref: EMBL:BC064830 xref: HGNC:HGNC:11536 xref: UniGene:Hs.122752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056881 ! TAF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020134 name: TAF3_human def: "Transcription initiation factor TFIID subunit 3 gene" [UniProtKB:Q5VWG9] xref: EMBL:AJ292190 xref: EMBL:AL117661 xref: EMBL:AL159172 xref: EMBL:AL353754 xref: EMBL:AL390294 xref: EMBL:BC045106 xref: EMBL:BC062352 xref: EMBL:BC073884 xref: HGNC:HGNC:17303 xref: UniGene:Hs.699383 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056663 ! TAF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020135 name: TAF4B_human def: "Transcription initiation factor TFIID subunit 4B gene" [UniProtKB:Q92750] synonym: "TAF2C2" EXACT [UniProtKB:Q92750] synonym: "TAFII105" EXACT [UniProtKB:Q92750] synonym: "TAFII105ALPHA" EXACT [UniProtKB:Q92750] xref: EMBL:AY888048 xref: EMBL:AY888049 xref: EMBL:Y09321 xref: HGNC:HGNC:11538 xref: UniGene:Hs.369519 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058088 ! TAF4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020136 name: TAF4_human def: "Transcription initiation factor TFIID subunit 4 gene" [UniProtKB:O00268] synonym: "TAF2C" EXACT [UniProtKB:O00268] synonym: "TAF2C1" EXACT [UniProtKB:O00268] synonym: "TAF4A" EXACT [UniProtKB:O00268] synonym: "TAFII130" EXACT [UniProtKB:O00268] synonym: "TAFII135" EXACT [UniProtKB:O00268] xref: EMBL:AL109911 xref: EMBL:AL137077 xref: EMBL:AY623115 xref: EMBL:CH471077 xref: EMBL:U75308 xref: EMBL:Y11354 xref: HGNC:HGNC:11537 xref: UniGene:Hs.18857 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054305 ! TAF4_HUMAN relationship: codes_for CCO:B0056606 ! Q5TBP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020137 name: TAF5L_human def: "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L gene" [UniProtKB:O75529] synonym: "PAF65B" EXACT [UniProtKB:O75529] xref: EMBL:AF069736 xref: EMBL:AJ009770 xref: EMBL:AL121990 xref: EMBL:BC041094 xref: EMBL:CH471098 xref: HGNC:HGNC:17304 xref: UniGene:Hs.270621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019363 ! TAF5L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020138 name: TAF6L_human def: "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L gene" [UniProtKB:Q9Y6J9] synonym: "PAF65A" EXACT [UniProtKB:Q9Y6J9] xref: EMBL:AF069735 xref: HGNC:HGNC:17305 xref: UniGene:Hs.131846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023501 ! TAF6L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020139 name: TAF7L_human def: "Transcription initiation factor TFIID subunit 7-like gene" [UniProtKB:Q5H9L4] synonym: "TAF2Q" EXACT [UniProtKB:Q5H9L4] xref: EMBL:AF285595 xref: EMBL:AK026810 xref: EMBL:AL109801 xref: EMBL:BC043391 xref: EMBL:CH471115 xref: EMBL:Z68331 xref: HGNC:HGNC:11548 xref: UniGene:Hs.223806 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056440 ! TAF7L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020140 name: TAF7_human def: "Transcription initiation factor TFIID subunit 7 gene" [UniProtKB:Q15545] synonym: "TAF2F" EXACT [UniProtKB:Q15545] synonym: "TAFII55" EXACT [UniProtKB:Q15545] xref: EMBL:AF349038 xref: EMBL:BC032737 xref: EMBL:U18062 xref: EMBL:X97999 xref: HGNC:HGNC:11541 xref: UniGene:Hs.438838 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056073 ! TAF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020141 name: TAF8_human def: "Transcription initiation factor TFIID subunit 8 gene" [UniProtKB:Q7Z7C8] synonym: "TAFII43" EXACT [UniProtKB:Q7Z7C8] synonym: "TBN" EXACT [UniProtKB:Q7Z7C8] xref: EMBL:AF465841 xref: EMBL:AK057383 xref: EMBL:AL512274 xref: EMBL:AL513008 xref: EMBL:BC033728 xref: EMBL:BC119678 xref: EMBL:BC119679 xref: HGNC:HGNC:17300 xref: UniGene:Hs.520122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057209 ! TAF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020142 name: TAGAP_human def: "T-cell activation Rho GTPase-activating protein gene" [UniProtKB:Q8N103] synonym: "FKSG15" EXACT [UniProtKB:Q8N103] synonym: "TAGAP1" EXACT [UniProtKB:Q8N103] xref: EMBL:AF314817 xref: EMBL:AF385429 xref: EMBL:AF385430 xref: EMBL:AK097090 xref: EMBL:AL035530 xref: EMBL:BC015859 xref: EMBL:BC111731 xref: HGNC:HGNC:15669 xref: UniGene:Hs.529984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020731 ! TAGAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020143 name: TAL1_human def: "T-cell acute lymphocytic leukemia protein 1 gene" [UniProtKB:P17542] synonym: "SCL" EXACT [UniProtKB:P17542] synonym: "TCL5" EXACT [UniProtKB:P17542] xref: EMBL:AL135960 xref: EMBL:M29038 xref: EMBL:M61103 xref: EMBL:M61104 xref: EMBL:M61105 xref: EMBL:M61108 xref: EMBL:M63572 xref: EMBL:M63576 xref: EMBL:M63584 xref: EMBL:M63589 xref: EMBL:X51990 xref: EMBL:X58621 xref: EMBL:X58622 xref: HGNC:HGNC:11556 xref: UniGene:Hs.525198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055090 ! TAL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020144 name: TAL2_human def: "T-cell acute lymphocytic leukemia protein 2 gene" [UniProtKB:Q16559] xref: EMBL:AL158070 xref: EMBL:BC069422 xref: EMBL:BC126373 xref: EMBL:BC126375 xref: EMBL:M81078 xref: EMBL:S69377 xref: HGNC:HGNC:11557 xref: UniGene:Hs.247978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056151 ! TAL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020145 name: TANK_human def: "TRAF family member-associated NF-kappa-B activator gene" [UniProtKB:Q92844] synonym: "ITRAF" EXACT [UniProtKB:Q92844] synonym: "TRAF2" EXACT [UniProtKB:Q92844] xref: EMBL:BC003388 xref: EMBL:U59863 xref: EMBL:U63830 xref: HGNC:HGNC:11562 xref: UniGene:Hs.556496 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058103 ! TANK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020146 name: TAOK2_human def: "Serine/threonine-protein kinase TAO2 gene" [UniProtKB:Q9UL54] synonym: "KIAA0881" EXACT [UniProtKB:Q9UL54] synonym: "MAP3K17" EXACT [UniProtKB:Q9UL54] synonym: "PSK" EXACT [UniProtKB:Q9UL54] synonym: "PSK1" EXACT [UniProtKB:Q9UL54] synonym: "UNQ2971/PRO7431" EXACT [UniProtKB:Q9UL54] xref: EMBL:AB020688 xref: EMBL:AF061943 xref: EMBL:AF263313 xref: EMBL:AL137701 xref: EMBL:AY358942 xref: HGNC:HGNC:16835 xref: UniGene:Hs.291623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019513 ! TAOK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020147 name: TAOK3_human def: "Serine/threonine-protein kinase TAO3 gene" [UniProtKB:Q9H2K8] synonym: "DPK" EXACT [UniProtKB:Q9H2K8] synonym: "JIK" EXACT [UniProtKB:Q9H2K8] synonym: "KDS" EXACT [UniProtKB:Q9H2K8] synonym: "MAP3K18" EXACT [UniProtKB:Q9H2K8] xref: EMBL:AF135158 xref: EMBL:AF179867 xref: EMBL:AF181985 xref: EMBL:AF263311 xref: EMBL:AF328731 xref: EMBL:AL833731 xref: EMBL:BC002756 xref: EMBL:BT007185 xref: HGNC:HGNC:18133 xref: UniGene:Hs.644420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019510 ! TAOK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020148 name: CCDC59_human def: "Thyroid transcription factor 1-associated protein 26 gene" [UniProtKB:Q9P031] synonym: "BR22" EXACT [UniProtKB:Q9P031] synonym: "HSPC128" EXACT [UniProtKB:Q9P031] synonym: "TAP26" EXACT [UniProtKB:Q9P031] xref: EMBL:AF161477 xref: EMBL:AF213377 xref: EMBL:AK001156 xref: EMBL:BC020647 xref: HGNC:HGNC:25005 xref: UniGene:Hs.582627 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059025 ! TAP26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020149 name: TRIOBP_human def: "TRIO and F-actin-binding protein gene" [UniProtKB:Q9H2D6] synonym: "HRIHFB2122" EXACT [UniProtKB:Q9H2D6] synonym: "KIAA1662" EXACT [UniProtKB:Q9H2D6] synonym: "TARA" EXACT [UniProtKB:Q9H2D6] xref: EMBL:AB015343 xref: EMBL:AB051449 xref: EMBL:AF281030 xref: EMBL:BC003618 xref: EMBL:BC004303 xref: EMBL:BC013278 xref: EMBL:DQ228003 xref: EMBL:DQ228004 xref: EMBL:DQ228005 xref: EMBL:DQ278603 xref: EMBL:Z83844 xref: HGNC:HGNC:17009 xref: UniGene:Hs.533030 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058684 ! TARA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020150 name: TARBP1_human def: "Probable methyltransferase TARBP1 gene" [UniProtKB:Q13395] synonym: "TRM3" EXACT [UniProtKB:Q13395] synonym: "TRP185" EXACT [UniProtKB:Q13395] xref: EMBL:AL136124 xref: EMBL:AL355472 xref: EMBL:U38847 xref: HGNC:HGNC:11568 xref: UniGene:Hs.498115 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055905 ! TARB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020151 name: MAPT_human def: "Microtubule-associated protein tau gene" [UniProtKB:P10636] synonym: "MAPTL" EXACT [UniProtKB:P10636] synonym: "MTBT1" EXACT [UniProtKB:P10636] synonym: "TAU" EXACT [UniProtKB:P10636] xref: EMBL:AF027491 xref: EMBL:AF027492 xref: EMBL:AF027493 xref: EMBL:AF027494 xref: EMBL:AF027495 xref: EMBL:AF027496 xref: EMBL:AF047856 xref: EMBL:AF047857 xref: EMBL:AF047858 xref: EMBL:AF047859 xref: EMBL:AF047860 xref: EMBL:AF047861 xref: EMBL:AF047862 xref: EMBL:AF047863 xref: EMBL:AY526356 xref: EMBL:AY730549 xref: EMBL:BC000558 xref: EMBL:BC098281 xref: EMBL:BC099721 xref: EMBL:BC101936 xref: EMBL:BC114504 xref: EMBL:BC114948 xref: EMBL:BN000503 xref: EMBL:BT006772 xref: EMBL:J03778 xref: EMBL:M25298 xref: EMBL:X14474 xref: HGNC:HGNC:6893 xref: UniGene:Hs.101174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054976 ! TAU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020152 name: TAX1BP1_human def: "Tax1-binding protein 1 gene" [UniProtKB:Q86VP1] synonym: "PRO0105" EXACT [UniProtKB:Q86VP1] synonym: "T6BP" EXACT [UniProtKB:Q86VP1] xref: EMBL:AC004549 xref: EMBL:AC005091 xref: EMBL:AF090891 xref: EMBL:AF268075 xref: EMBL:AL136586 xref: EMBL:BC050358 xref: EMBL:CR457056 xref: EMBL:CR533556 xref: EMBL:U33821 xref: HGNC:HGNC:11575 xref: UniGene:Hs.34576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057266 ! TAXB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020153 name: TBC1D10A_human def: "TBC1 domain family member 10A gene" [UniProtKB:Q9BXI6] synonym: "EPI64" EXACT [UniProtKB:Q9BXI6] synonym: "TBC1D10" EXACT [UniProtKB:Q9BXI6] xref: EMBL:AC004997 xref: EMBL:AF331038 xref: EMBL:AK074656 xref: EMBL:BC150187 xref: HGNC:HGNC:23609 xref: UniGene:Hs.655273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053944 ! A7E244_HUMAN relationship: codes_for CCO:B0058554 ! TB10A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020154 name: TBC1D10B_human def: "TBC1 domain family member 10B gene" [UniProtKB:Q4KMP7] synonym: "FP2461" EXACT [UniProtKB:Q4KMP7] xref: EMBL:AF370370 xref: EMBL:AK002101 xref: EMBL:AK023192 xref: EMBL:AL117408 xref: EMBL:BC050523 xref: EMBL:BC063112 xref: EMBL:BC072453 xref: EMBL:BC093814 xref: EMBL:BC093816 xref: EMBL:BC098419 xref: EMBL:CH471192 xref: HGNC:HGNC:24510 xref: UniGene:Hs.699204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056319 ! TB10B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020155 name: TBC1D10C_human def: "Carabin gene" [UniProtKB:Q8IV04] xref: EMBL:BC036873 xref: EMBL:BC062999 xref: HGNC:HGNC:24702 xref: UniGene:Hs.534648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057332 ! TB10C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020156 name: TBC1D22A_human def: "TBC1 domain family member 22A gene" [UniProtKB:Q8WUA7] synonym: "C22orf4" EXACT [UniProtKB:Q8WUA7] xref: EMBL:AK125705 xref: EMBL:AK127653 xref: EMBL:AL023733 xref: EMBL:AL096755 xref: EMBL:AL096779 xref: EMBL:AL118516 xref: EMBL:BC001292 xref: EMBL:BC002743 xref: EMBL:BC020976 xref: EMBL:BC029897 xref: EMBL:CH471138 xref: EMBL:CR456412 xref: EMBL:U51561 xref: EMBL:Z79999 xref: EMBL:Z80896 xref: EMBL:Z82187 xref: HGNC:HGNC:1309 xref: UniGene:Hs.435044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030729 ! TB22A_HUMAN relationship: codes_for CCO:B0054165 ! B0QYI1_HUMAN relationship: codes_for CCO:B0054166 ! B0QYI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020157 name: TBC1D22B_human def: "TBC1 domain family member 22B gene" [UniProtKB:Q9NU19] synonym: "C6orf197" EXACT [UniProtKB:Q9NU19] xref: EMBL:AK000344 xref: EMBL:AL096712 xref: EMBL:AL353579 xref: EMBL:AL589667 xref: EMBL:AY313781 xref: EMBL:BC000291 xref: EMBL:BC000743 xref: EMBL:BC001927 xref: EMBL:BC002720 xref: EMBL:BC109026 xref: EMBL:BC109027 xref: HGNC:HGNC:21602 xref: UniGene:Hs.485270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030726 ! TB22B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020158 name: TBC1D12_human def: "TBC1 domain family member 12 gene" [UniProtKB:O60347] synonym: "KIAA0608" EXACT [UniProtKB:O60347] xref: EMBL:AB011180 xref: EMBL:AL049956 xref: EMBL:AL138759 xref: EMBL:AL355341 xref: HGNC:HGNC:29082 xref: UniGene:Hs.500598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054548 ! TBC12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020159 name: TBC1D14_human def: "TBC1 domain family member 14 gene" [UniProtKB:Q9P2M4] synonym: "KIAA1322" EXACT [UniProtKB:Q9P2M4] xref: EMBL:AB037743 xref: EMBL:AL833868 xref: EMBL:BC041167 xref: HGNC:HGNC:29246 xref: UniGene:Hs.518611 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059060 ! TBC14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020160 name: TBC1D15_human def: "TBC1 domain family member 15 gene" [UniProtKB:Q8TC07] xref: EMBL:AK022147 xref: EMBL:AK292306 xref: EMBL:BC028352 xref: EMBL:CH471054 xref: HGNC:HGNC:25694 xref: UniGene:Hs.284630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053979 ! A8K8E1_HUMAN relationship: codes_for CCO:B0057910 ! TBC15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020161 name: TBC1D16_human def: "TBC1 domain family member 16 gene" [UniProtKB:Q8TBP0] xref: EMBL:BC001525 xref: EMBL:BC028290 xref: HGNC:HGNC:28356 xref: UniGene:Hs.369819 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057906 ! TBC16_HUMAN relationship: codes_for CCO:B0058193 ! Q96DH7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020162 name: TBC1D19_human def: "TBC1 domain family member 19 gene" [UniProtKB:Q8N5T2] xref: EMBL:AK001944 xref: EMBL:BC031642 xref: HGNC:HGNC:25624 xref: UniGene:Hs.479403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057478 ! TBC19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020163 name: TBC1D20_human def: "TBC1 domain family member 20 gene" [UniProtKB:Q96BZ9] synonym: "C20orf140" EXACT [UniProtKB:Q96BZ9] xref: EMBL:AK055573 xref: EMBL:AK127062 xref: EMBL:AK291648 xref: EMBL:AL049761 xref: EMBL:AL121747 xref: EMBL:BC014983 xref: EMBL:CH471133 xref: HGNC:HGNC:16133 xref: UniGene:Hs.590876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058172 ! TBC20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020164 name: TBC1D21_human def: "TBC1 domain family member 21 gene" [UniProtKB:Q8IYX1] xref: EMBL:BC033516 xref: HGNC:HGNC:28536 xref: UniGene:Hs.124512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057394 ! TBC21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020165 name: TBC1D23_human def: "TBC1 domain family member 23 gene" [UniProtKB:Q9NUY8] synonym: "NS4ATP1" EXACT [UniProtKB:Q9NUY8] xref: EMBL:AK001750 xref: EMBL:AK001908 xref: EMBL:AL713684 xref: EMBL:AY740521 xref: EMBL:BC010221 xref: EMBL:BC020955 xref: HGNC:HGNC:25622 xref: UniGene:Hs.477003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058928 ! TBC23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020166 name: TBC1D24_human def: "TBC1 domain family member 24 gene" [UniProtKB:Q9ULP9] synonym: "KIAA1171" EXACT [UniProtKB:Q9ULP9] xref: EMBL:AB032997 xref: EMBL:BC112389 xref: EMBL:BC127014 xref: EMBL:BC127015 xref: HGNC:HGNC:29203 xref: UniGene:Hs.353087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059231 ! TBC24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020167 name: TBC1D25_human def: "TBC1 domain family member 25 gene" [UniProtKB:Q3MII6] synonym: "OATL1" EXACT [UniProtKB:Q3MII6] xref: EMBL:BC026050 xref: EMBL:BC101817 xref: EMBL:BC101819 xref: EMBL:BC125088 xref: EMBL:BC125089 xref: HGNC:HGNC:8092 xref: UniGene:Hs.30619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056262 ! TBC25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020168 name: TBC1D26_human def: "TBC1 domain family member 26 gene" [UniProtKB:Q86UD7] xref: EMBL:AC005324 xref: EMBL:AK292544 xref: EMBL:AK315847 xref: EMBL:BC028414 xref: EMBL:BC047400 xref: HGNC:HGNC:28745 xref: UniGene:Hs.567880 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057247 ! TBC26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020169 name: TBC1D28_human def: "TBC1 domain family member 28 gene" [UniProtKB:Q2M2D7] xref: EMBL:BC112012 xref: EMBL:BC112016 xref: HGNC:HGNC:26858 xref: UniGene:Hs.434123 xref: UniGene:Hs.567880 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056210 ! TBC28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020170 name: TBC1D29_human def: "Putative TBC1 domain family member 29 gene" [UniProtKB:Q9UFV1] xref: EMBL:AL117394 xref: EMBL:BC096718 xref: EMBL:BC098126 xref: EMBL:CH471159 xref: HGNC:HGNC:24509 xref: UniGene:Hs.241421 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056326 ! Q4V771_HUMAN relationship: codes_for CCO:B0059116 ! TBC29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020171 name: TBC1D30_human def: "TBC1 domain family member 30 gene" [UniProtKB:Q9Y2I9] synonym: "KIAA0984" EXACT [UniProtKB:Q9Y2I9] xref: EMBL:AB023201 xref: EMBL:AC025262 xref: EMBL:AC078815 xref: HGNC:HGNC:29164 xref: UniGene:Hs.192492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059308 ! TBC30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020172 name: TBC1D3_human def: "TBC1 domain family member 3 gene" [UniProtKB:Q8IZP1] synonym: "PRC17" EXACT [UniProtKB:Q8IZP1] synonym: "TBC1D3A" EXACT [UniProtKB:Q8IZP1] xref: EMBL:AC021317 xref: EMBL:AF540953 xref: EMBL:AL136860 xref: EMBL:BC078140 xref: EMBL:X71377 xref: HGNC:HGNC:19031 xref: UniGene:Hs.105891 xref: UniGene:Hs.617010 xref: UniGene:Hs.655470 xref: UniGene:Hs.677656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056722 ! Q6DCB4_HUMAN relationship: codes_for CCO:B0057411 ! TBC3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020173 name: TBC1D3B_human def: "TBC1 domain family member 3B/I gene" [UniProtKB:A6NDS4] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053796 ! TBC3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020174 name: TBC1D3I_human def: "TBC1 domain family member 3B/I gene" [UniProtKB:A6NDS4] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053796 ! TBC3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020175 name: TBC1D3C_human def: "TBC1 domain family member 3C/3D gene" [UniProtKB:Q6IPX1] xref: EMBL:AC131056 xref: HGNC:HGNC:24889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053830 ! A6NG99_HUMAN relationship: codes_for CCO:B0056822 ! TBC3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020176 name: TBC1D3D_human def: "TBC1 domain family member 3C/3D gene" [UniProtKB:Q6IPX1] xref: EMBL:AC021317 xref: HGNC:HGNC:28944 xref: UniGene:Hs.655470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054031 ! A8MTM7_HUMAN relationship: codes_for CCO:B0056822 ! TBC3C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020177 name: TBC1D3G_human def: "TBC1 domain family member 3G gene" [UniProtKB:Q6DHY5] xref: EMBL:AC126327 xref: EMBL:BC075809 xref: HGNC:HGNC:29860 xref: UniGene:Hs.617010 xref: UniGene:Hs.661995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054053 ! A8MV28_HUMAN relationship: codes_for CCO:B0056724 ! TBC3G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020178 name: TBC1D8B_human def: "TBC1 domain family member 8B gene" [UniProtKB:Q0IIM8] xref: EMBL:AK000305 xref: EMBL:AK123957 xref: EMBL:AL391315 xref: EMBL:AL591849 xref: EMBL:BC122564 xref: HGNC:HGNC:24715 xref: UniGene:Hs.351798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055812 ! TBC8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020179 name: TBC1D9B_human def: "TBC1 domain family member 9B gene" [UniProtKB:Q66K14] synonym: "KIAA0676" EXACT [UniProtKB:Q66K14] xref: EMBL:AB014576 xref: EMBL:AK223509 xref: EMBL:BC008919 xref: EMBL:BC080659 xref: EMBL:BX641107 xref: HGNC:HGNC:29097 xref: UniGene:Hs.155829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056695 ! TBC9B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020180 name: TBC1D1_human def: "TBC1 domain family member 1 gene" [UniProtKB:Q86TI0] synonym: "KIAA1108" EXACT [UniProtKB:Q86TI0] xref: EMBL:AB029031 xref: EMBL:AK027355 xref: EMBL:BC050321 xref: EMBL:BC126979 xref: HGNC:HGNC:11578 xref: UniGene:Hs.176503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027580 ! A0JNU9_HUMAN relationship: codes_for CCO:B0027581 ! TBCD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020181 name: TBC1D5_human def: "TBC1 domain family member 5 gene" [UniProtKB:Q92609] synonym: "KIAA0210" EXACT [UniProtKB:Q92609] xref: EMBL:AC090644 xref: EMBL:BC013145 xref: EMBL:D86965 xref: HGNC:HGNC:19166 xref: UniGene:Hs.475629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058070 ! TBCD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020182 name: TBC1D7_human def: "TBC1 domain family member 7 gene" [UniProtKB:Q9P0N9] synonym: "HSPC239" EXACT [UniProtKB:Q9P0N9] xref: EMBL:AF151073 xref: EMBL:AL589984 xref: EMBL:AY826820 xref: EMBL:BC007054 xref: EMBL:BC050465 xref: EMBL:CH471087 xref: HGNC:HGNC:21066 xref: UniGene:Hs.484678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056554 ! Q5SZL4_HUMAN relationship: codes_for CCO:B0056555 ! Q5SZL5_HUMAN relationship: codes_for CCO:B0056556 ! Q5SZL8_HUMAN relationship: codes_for CCO:B0056557 ! Q5SZM1_HUMAN relationship: codes_for CCO:B0056558 ! Q5SZM2_HUMAN relationship: codes_for CCO:B0057264 ! Q86VM8_HUMAN relationship: codes_for CCO:B0059033 ! TBCD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020183 name: TBC1D8_human def: "TBC1 domain family member 8 gene" [UniProtKB:O95759] synonym: "VRP" EXACT [UniProtKB:O95759] xref: EMBL:AB017114 xref: EMBL:AB024057 xref: EMBL:AC016738 xref: HGNC:HGNC:17791 xref: UniGene:Hs.442657 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054793 ! TBCD8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020184 name: TBC1D9_human def: "TBC1 domain family member 9 gene" [UniProtKB:Q6ZT07] synonym: "KIAA0882" EXACT [UniProtKB:Q6ZT07] xref: EMBL:AB020689 xref: EMBL:AK127020 xref: HGNC:HGNC:21710 xref: UniGene:Hs.480819 xref: UniGene:Hs.694161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057062 ! TBCD9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020185 name: TBCK_human def: "TBC domain-containing protein kinase-like protein gene" [UniProtKB:Q8TEA7] synonym: "HSPC302" EXACT [UniProtKB:Q8TEA7] xref: EMBL:AC093680 xref: EMBL:AC107381 xref: EMBL:AC109361 xref: EMBL:AC114734 xref: EMBL:AC125469 xref: EMBL:AF161420 xref: EMBL:AK074305 xref: EMBL:AK098157 xref: EMBL:AP001820 xref: EMBL:BC009208 xref: EMBL:BC020853 xref: EMBL:BC068496 xref: UniGene:Hs.292986 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057953 ! TBCK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020186 name: TBC1D2_human def: "TBC1 domain family member 2A gene" [UniProtKB:Q9BYX2] synonym: "PARIS1" EXACT [UniProtKB:Q9BYX2] synonym: "TBC1D2A" EXACT [UniProtKB:Q9BYX2] xref: EMBL:AL137073 xref: EMBL:AL360081 xref: EMBL:AL591502 xref: EMBL:AY026527 xref: EMBL:BC028918 xref: EMBL:CH471105 xref: HGNC:HGNC:18026 xref: UniGene:Hs.371016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056607 ! Q5TBQ6_HUMAN relationship: codes_for CCO:B0056608 ! Q5TBQ7_HUMAN relationship: codes_for CCO:B0057114 ! Q7L1K8_HUMAN relationship: codes_for CCO:B0058586 ! TBD2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020187 name: TBC1D2B_human def: "TBC1 domain family member 2B gene" [UniProtKB:Q9UPU7] synonym: "KIAA1055" EXACT [UniProtKB:Q9UPU7] xref: EMBL:AB028978 xref: EMBL:AC090260 xref: EMBL:AC104758 xref: EMBL:AK000173 xref: EMBL:BC033712 xref: EMBL:BC152465 xref: EMBL:CH471136 xref: HGNC:HGNC:29183 xref: UniGene:Hs.567426 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059268 ! TBD2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020188 name: TBL1X_human def: "F-box-like/WD repeat-containing protein TBL1X gene" [UniProtKB:O60907] synonym: "TBL1" EXACT [UniProtKB:O60907] xref: EMBL:BC032708 xref: EMBL:BC052304 xref: EMBL:Y12781 xref: HGNC:HGNC:11585 xref: UniGene:Hs.699315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054590 ! TBL1X_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020189 name: TBL1Y_human def: "F-box-like/WD repeat-containing protein TBL1Y gene" [UniProtKB:Q9BQ87] synonym: "TBL1" EXACT [UniProtKB:Q9BQ87] xref: EMBL:AF332220 xref: EMBL:AF332221 xref: EMBL:AF332222 xref: HGNC:HGNC:18502 xref: UniGene:Hs.664560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058477 ! TBL1Y_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020190 name: TBPL1_human def: "TATA box-binding protein-like protein 1 gene" [UniProtKB:P62380] synonym: "TLP" EXACT [UniProtKB:P62380] synonym: "TLP21" EXACT [UniProtKB:P62380] synonym: "TRF2" EXACT [UniProtKB:P62380] xref: EMBL:AB020881 xref: EMBL:AF130312 xref: EMBL:AF136570 xref: EMBL:AL035699 xref: EMBL:BC000381 xref: EMBL:BC017559 xref: HGNC:HGNC:11589 xref: UniGene:Hs.486507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055618 ! TBPL1_HUMAN relationship: codes_for CCO:B0057202 ! Q7Z6T9_HUMAN relationship: codes_for CCO:B0057203 ! Q7Z6U0_HUMAN relationship: codes_for CCO:B0057204 ! Q7Z6U1_HUMAN relationship: codes_for CCO:B0057205 ! Q7Z6U2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020191 name: TBR1_human def: "T-box brain protein 1 gene" [UniProtKB:Q16650] xref: EMBL:AC009487 xref: EMBL:BC104844 xref: EMBL:BC113418 xref: EMBL:U49250 xref: HGNC:HGNC:11590 xref: UniGene:Hs.705400 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056168 ! TBR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020192 name: TBX10_human def: "T-box transcription factor TBX10 gene" [UniProtKB:O75333] synonym: "TBX7" EXACT [UniProtKB:O75333] xref: EMBL:AF033574 xref: EMBL:AF033575 xref: EMBL:AF033576 xref: EMBL:AF033577 xref: EMBL:AF033578 xref: EMBL:AF033579 xref: EMBL:AY229977 xref: EMBL:BC113485 xref: EMBL:BC113487 xref: HGNC:HGNC:11593 xref: UniGene:Hs.454480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018676 ! TBX10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020193 name: TBX19_human def: "T-box transcription factor TBX19 gene" [UniProtKB:O60806] synonym: "TPIT" EXACT [UniProtKB:O60806] xref: EMBL:AJ010277 xref: EMBL:AL009051 xref: EMBL:BC093664 xref: EMBL:BC093666 xref: HGNC:HGNC:11596 xref: UniGene:Hs.645440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054580 ! TBX19_HUMAN relationship: codes_for CCO:B0056633 ! Q5TIH6_HUMAN relationship: codes_for CCO:B0056634 ! Q5TIH7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020194 name: TBX1_human def: "T-box transcription factor TBX1 gene" [UniProtKB:O43435] xref: EMBL:AF012130 xref: EMBL:AF012131 xref: EMBL:AF373867 xref: HGNC:HGNC:11592 xref: UniGene:Hs.173984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018668 ! TBX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020195 name: TBX20_human def: "T-box transcription factor TBX20 gene" [UniProtKB:Q9UMR3] xref: EMBL:AC006379 xref: EMBL:AJ237589 xref: EMBL:BC120945 xref: EMBL:BC120946 xref: EMBL:DQ986374 xref: HGNC:HGNC:11598 xref: UniGene:Hs.404167 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018672 ! Q000T4_HUMAN relationship: codes_for CCO:B0018678 ! TBX20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020196 name: TBX21_human def: "T-box transcription factor TBX21 gene" [UniProtKB:Q9UL17] synonym: "TBET" EXACT [UniProtKB:Q9UL17] synonym: "TBLYM" EXACT [UniProtKB:Q9UL17] xref: EMBL:AF093098 xref: EMBL:AF241243 xref: EMBL:BC039739 xref: HGNC:HGNC:11599 xref: UniGene:Hs.272409 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059213 ! TBX21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020197 name: TBX2_human def: "T-box transcription factor TBX2 gene" [UniProtKB:Q13207] xref: EMBL:BC052566 xref: EMBL:S81264 xref: EMBL:U28049 xref: HGNC:HGNC:11597 xref: UniGene:Hs.705451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055886 ! TBX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020198 name: TBX5_human def: "T-box transcription factor TBX5 gene" [UniProtKB:Q99593] xref: EMBL:AB051068 xref: EMBL:AC009260 xref: EMBL:AF221714 xref: EMBL:BC027942 xref: EMBL:CH471054 xref: EMBL:U80987 xref: EMBL:U89353 xref: EMBL:Y09445 xref: HGNC:HGNC:11604 xref: UniGene:Hs.381715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053789 ! A6ND77_HUMAN relationship: codes_for CCO:B0058405 ! Q96TB0_HUMAN relationship: codes_for CCO:B0058429 ! TBX5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020199 name: TBX6_human def: "T-box transcription factor TBX6 gene" [UniProtKB:O95947] xref: EMBL:AJ007989 xref: EMBL:AJ010279 xref: EMBL:AK022330 xref: EMBL:BC026031 xref: EMBL:CH471238 xref: HGNC:HGNC:11605 xref: UniGene:Hs.198301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018665 ! Q9HA44_HUMAN relationship: codes_for CCO:B0018670 ! TBX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020200 name: TCEAL1_human def: "Transcription elongation factor A protein-like 1 gene" [UniProtKB:Q15170] synonym: "SIIR" EXACT [UniProtKB:Q15170] xref: EMBL:AF095906 xref: EMBL:AL049610 xref: EMBL:BC000809 xref: EMBL:M99701 xref: HGNC:HGNC:11616 xref: UniGene:Hs.95243 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056048 ! TCAL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020201 name: TCEAL2_human def: "Transcription elongation factor A protein-like 2 gene" [UniProtKB:Q9H3H9] synonym: "My048" EXACT [UniProtKB:Q9H3H9] synonym: "MY0876G0" EXACT [UniProtKB:Q9H3H9] xref: EMBL:AF063606 xref: EMBL:AF325115 xref: EMBL:AL035214 xref: EMBL:BC093932 xref: EMBL:BC104764 xref: HGNC:HGNC:29818 xref: UniGene:Hs.401835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058702 ! TCAL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020202 name: TCEAL3_human def: "Transcription elongation factor A protein-like 3 gene" [UniProtKB:Q969E4] synonym: "MSTP072" EXACT [UniProtKB:Q969E4] xref: EMBL:AF163263 xref: EMBL:AK098494 xref: EMBL:BC007622 xref: EMBL:BC008703 xref: EMBL:Z73965 xref: HGNC:HGNC:28247 xref: UniGene:Hs.311776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058127 ! TCAL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020203 name: TCEAL4_human def: "Transcription elongation factor A protein-like 4 gene" [UniProtKB:Q96EI5] synonym: "NPD017" EXACT [UniProtKB:Q96EI5] xref: EMBL:AF271783 xref: EMBL:AF314542 xref: EMBL:AK024827 xref: EMBL:BC012296 xref: EMBL:Z73965 xref: HGNC:HGNC:26121 xref: UniGene:Hs.194329 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058206 ! TCAL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020204 name: TCEAL5_human def: "Transcription elongation factor A protein-like 5 gene" [UniProtKB:Q5H9L2] xref: EMBL:Z68694 xref: HGNC:HGNC:22282 xref: UniGene:Hs.403462 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056439 ! TCAL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020205 name: TCEAL6_human def: "Transcription elongation factor A protein-like 6 gene" [UniProtKB:Q6IPX3] xref: EMBL:BC071675 xref: EMBL:Z70719 xref: HGNC:HGNC:24553 xref: UniGene:Hs.447815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056823 ! TCAL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020206 name: TCEAL7_human def: "Transcription elongation factor A protein-like 7 gene" [UniProtKB:Q9BRU2] xref: EMBL:BC005988 xref: EMBL:BC016786 xref: EMBL:Z92846 xref: HGNC:HGNC:28336 xref: UniGene:Hs.21861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058498 ! TCAL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020207 name: TCEAL8_human def: "Transcription elongation factor A protein-like 8 gene" [UniProtKB:Q8IYN2] xref: EMBL:BC035573 xref: EMBL:Z68694 xref: HGNC:HGNC:28683 xref: UniGene:Hs.389734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057391 ! TCAL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020208 name: TICAM1_human def: "TIR domain-containing adapter molecule 1 gene" [UniProtKB:Q8IUC6] synonym: "PRVTIRB" EXACT [UniProtKB:Q8IUC6] synonym: "TRIF" EXACT [UniProtKB:Q8IUC6] xref: EMBL:AB086380 xref: EMBL:AB093555 xref: EMBL:AB097023 xref: EMBL:AF070530 xref: EMBL:AF492646 xref: EMBL:BC009860 xref: HGNC:HGNC:18348 xref: UniGene:Hs.29344 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057321 ! TCAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020209 name: TICAM2_human def: "TIR domain-containing adapter molecule 2 gene" [UniProtKB:Q86XR7] synonym: "TIRAP3" EXACT [UniProtKB:Q86XR7] synonym: "TIRP" EXACT [UniProtKB:Q86XR7] synonym: "TRAM" EXACT [UniProtKB:Q86XR7] xref: EMBL:AB091054 xref: EMBL:AB097022 xref: EMBL:AB109098 xref: EMBL:AY232653 xref: EMBL:AY275836 xref: EMBL:AY304582 xref: EMBL:AY304583 xref: EMBL:BC109265 xref: EMBL:BC109266 xref: EMBL:CH471086 xref: HGNC:HGNC:21354 xref: UniGene:Hs.705455 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057293 ! TCAM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020210 name: TCEA1_human def: "Transcription elongation factor A protein 1 gene" [UniProtKB:P23193] synonym: "GTF2S" EXACT [UniProtKB:P23193] synonym: "TFIIS" EXACT [UniProtKB:P23193] xref: EMBL:BC072460 xref: EMBL:BT019995 xref: EMBL:CR542221 xref: EMBL:M81601 xref: EMBL:X57198 xref: EMBL:X62585 xref: EMBL:X73534 xref: HGNC:HGNC:11612 xref: UniGene:Hs.491745 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055153 ! TCEA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020211 name: TCEA3_human def: "Transcription elongation factor A protein 3 gene" [UniProtKB:O75764] synonym: "TFIISH" EXACT [UniProtKB:O75764] xref: EMBL:AJ223473 xref: EMBL:BC041613 xref: HGNC:HGNC:11615 xref: UniGene:Hs.446354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015243 ! TCEA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020212 name: TCF15_human def: "Transcription factor 15 gene" [UniProtKB:Q12870] synonym: "BHLHEC2" EXACT [UniProtKB:Q12870] xref: EMBL:AL133231 xref: EMBL:U08336 xref: HGNC:HGNC:11627 xref: UniGene:Hs.437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055852 ! TCF15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020213 name: TCF20_human def: "Transcription factor 20 gene" [UniProtKB:Q9UGU0] synonym: "KIAA0292" EXACT [UniProtKB:Q9UGU0] synonym: "SPBP" EXACT [UniProtKB:Q9UGU0] xref: EMBL:AB006630 xref: EMBL:AL031346 xref: EMBL:AY007595 xref: EMBL:BX247885 xref: EMBL:U19345 xref: HGNC:HGNC:11631 xref: UniGene:Hs.475018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059126 ! TCF20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020214 name: TCF21_human def: "Transcription factor 21 gene" [UniProtKB:O43680] synonym: "POD1" EXACT [UniProtKB:O43680] xref: EMBL:AF035718 xref: EMBL:AF047419 xref: EMBL:AL356109 xref: EMBL:BC025697 xref: EMBL:BT019660 xref: HGNC:HGNC:11632 xref: UniGene:Hs.78061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054510 ! TCF21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020215 name: TCF23_human def: "Transcription factor 23 gene" [UniProtKB:Q7RTU1] xref: EMBL:AC013403 xref: EMBL:BK000143 xref: HGNC:HGNC:18602 xref: UniGene:Hs.591583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057133 ! TCF23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020216 name: TCF25_human def: "Transcription factor 25 gene" [UniProtKB:Q9BQ70] synonym: "FKSG26" EXACT [UniProtKB:Q9BQ70] synonym: "KIAA1049" EXACT [UniProtKB:Q9BQ70] synonym: "NULP1" EXACT [UniProtKB:Q9BQ70] xref: EMBL:AB028972 xref: EMBL:AF322111 xref: EMBL:BC000959 xref: EMBL:BC009349 xref: EMBL:BC011884 xref: EMBL:DQ321703 xref: HGNC:HGNC:29181 xref: UniGene:Hs.415342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058475 ! TCF25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020217 name: TCF7_human def: "Transcription factor 7 gene" [UniProtKB:P36402] synonym: "TCF1" EXACT [UniProtKB:P36402] xref: EMBL:AF163776 xref: EMBL:BC048769 xref: EMBL:BC072023 xref: EMBL:CH471062 xref: EMBL:X59869 xref: EMBL:X59870 xref: EMBL:X59871 xref: EMBL:X63901 xref: EMBL:Z47361 xref: EMBL:Z47362 xref: EMBL:Z47363 xref: EMBL:Z47364 xref: HGNC:HGNC:11639 xref: UniGene:Hs.573153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055306 ! TCF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020218 name: TCFL5_human def: "Transcription factor-like 5 protein gene" [UniProtKB:Q9UL49] synonym: "CHA" EXACT [UniProtKB:Q9UL49] synonym: "E2BP1" EXACT [UniProtKB:Q9UL49] xref: EMBL:AB012124 xref: EMBL:AF070992 xref: EMBL:AJ271337 xref: EMBL:AL035669 xref: HGNC:HGNC:11646 xref: UniGene:Hs.699411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059217 ! TCFL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020219 name: SNX26_human def: "TC10/CDC42 GTPase-activating protein gene" [UniProtKB:O14559] synonym: "TCGAP" EXACT [UniProtKB:O14559] xref: EMBL:AC002398 xref: EMBL:AK096338 xref: EMBL:AK127255 xref: EMBL:AL137579 xref: EMBL:AY044864 xref: EMBL:BC014084 xref: HGNC:HGNC:23085 xref: UniGene:Hs.515364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054352 ! TCGAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020220 name: TDG_human def: "G/T mismatch-specific thymine DNA glycosylase gene" [UniProtKB:Q13569] xref: EMBL:AF545435 xref: EMBL:BC037557 xref: EMBL:U51166 xref: HGNC:HGNC:11700 xref: UniGene:Hs.584809 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055930 ! TDG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020221 name: DNTTIP2_human def: "Deoxynucleotidyltransferase terminal-interacting protein 2 gene" [UniProtKB:Q5QJE6] synonym: "ERBP" EXACT [UniProtKB:Q5QJE6] synonym: "TDIF2" EXACT [UniProtKB:Q5QJE6] xref: EMBL:AB046574 xref: EMBL:AK222722 xref: EMBL:AK292379 xref: EMBL:AL049796 xref: EMBL:AY336729 xref: EMBL:AY394925 xref: EMBL:BC047688 xref: EMBL:BC130622 xref: EMBL:CH471097 xref: EMBL:U15552 xref: HGNC:HGNC:24013 xref: UniGene:Hs.85769 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056526 ! TDIF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020222 name: DNTT_human def: "DNA nucleotidylexotransferase gene" [UniProtKB:P04053] synonym: "TDT" EXACT [UniProtKB:P04053] xref: EMBL:AB046378 xref: EMBL:BC012920 xref: EMBL:K01919 xref: EMBL:M11722 xref: EMBL:M20694 xref: EMBL:M20695 xref: EMBL:M20696 xref: EMBL:M20697 xref: EMBL:M20698 xref: EMBL:M20699 xref: EMBL:M20700 xref: EMBL:M20701 xref: EMBL:M20702 xref: EMBL:M20703 xref: EMBL:M21195 xref: EMBL:M22968 xref: HGNC:HGNC:2983 xref: UniGene:Hs.534206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054882 ! TDT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020223 name: TEAD1_human def: "Transcriptional enhancer factor TEF-1 gene" [UniProtKB:P28347] synonym: "TCF13" EXACT [UniProtKB:P28347] synonym: "TEF1" EXACT [UniProtKB:P28347] xref: EMBL:BC115398 xref: EMBL:M63896 xref: HGNC:HGNC:11714 xref: UniGene:Hs.655331 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032274 ! A4FUP2_HUMAN relationship: codes_for CCO:B0032277 ! TEAD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020224 name: TEAD2_human def: "Transcriptional enhancer factor TEF-4 gene" [UniProtKB:Q15562] synonym: "TEF4" EXACT [UniProtKB:Q15562] xref: EMBL:AK093236 xref: EMBL:AK290736 xref: EMBL:BC007556 xref: EMBL:BC051301 xref: EMBL:CH471177 xref: EMBL:X94440 xref: HGNC:HGNC:11715 xref: UniGene:Hs.515534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032268 ! TEAD2_HUMAN relationship: codes_for CCO:B0032270 ! Q8NA25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020225 name: TEAD3_human def: "Transcriptional enhancer factor TEF-5 gene" [UniProtKB:Q99594] synonym: "TEAD5" EXACT [UniProtKB:Q99594] synonym: "TEF5" EXACT [UniProtKB:Q99594] xref: EMBL:AL022721 xref: EMBL:BC027877 xref: EMBL:BC091488 xref: EMBL:X94439 xref: HGNC:HGNC:11716 xref: UniGene:Hs.485205 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032261 ! TEAD3_HUMAN relationship: codes_for CCO:B0032263 ! Q7Z6U9_HUMAN relationship: codes_for CCO:B0032267 ! Q7Z6U7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020226 name: PTGES3_human def: "Prostaglandin E synthase 3 gene" [UniProtKB:Q15185] synonym: "P23" EXACT [UniProtKB:Q15185] synonym: "TEBP" EXACT [UniProtKB:Q15185] xref: EMBL:BC003005 xref: EMBL:BC021167 xref: EMBL:L24804 xref: HGNC:HGNC:16049 xref: UniGene:Hs.50425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056049 ! TEBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020227 name: TEC_human def: "Tyrosine-protein kinase Tec gene" [UniProtKB:P42680] synonym: "PSCTK4" EXACT [UniProtKB:P42680] xref: EMBL:BC101711 xref: EMBL:BC101713 xref: EMBL:D29767 xref: HGNC:HGNC:11719 xref: UniGene:Hs.479670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055353 ! TEC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020228 name: TEF_human def: "Thyrotroph embryonic factor gene" [UniProtKB:Q10587] synonym: "KIAA1655" EXACT [UniProtKB:Q10587] xref: EMBL:AK091916 xref: EMBL:AL035659 xref: EMBL:BC039258 xref: EMBL:BC042476 xref: EMBL:BX537848 xref: EMBL:CH471095 xref: EMBL:CR456592 xref: EMBL:CR541827 xref: EMBL:U06935 xref: EMBL:U44059 xref: HGNC:HGNC:11722 xref: UniGene:Hs.181159 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054169 ! B0QYS8_HUMAN relationship: codes_for CCO:B0055835 ! TEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020229 name: ODZ1_human def: "Teneurin-1 gene" [UniProtKB:Q9UKZ4] synonym: "TNM1" EXACT [UniProtKB:Q9UKZ4] xref: EMBL:AF100772 xref: EMBL:AL022718 xref: EMBL:AL023878 xref: EMBL:AL031075 xref: EMBL:Z81008 xref: EMBL:Z83823 xref: EMBL:Z85995 xref: HGNC:HGNC:8117 xref: UniGene:Hs.23796 xref: UniGene:Hs.688900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059211 ! TEN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020230 name: TENC1_human def: "Tensin-like C1 domain-containing phosphatase gene" [UniProtKB:Q63HR2] synonym: "KIAA1075" EXACT [UniProtKB:Q63HR2] synonym: "TNS2" EXACT [UniProtKB:Q63HR2] xref: EMBL:AB028998 xref: EMBL:AF417490 xref: EMBL:AF518728 xref: EMBL:AF518729 xref: EMBL:AL137564 xref: EMBL:BC054099 xref: EMBL:BC110854 xref: EMBL:BC129828 xref: EMBL:BC129829 xref: EMBL:BC131503 xref: EMBL:BX647126 xref: HGNC:HGNC:19737 xref: UniGene:Hs.343334 xref: UniGene:Hs.6147 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056690 ! TENC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020231 name: TNN_human def: "Tenascin-N precursor gene" [UniProtKB:Q9UQP3] xref: EMBL:AL049689 xref: EMBL:Z99297 xref: EMBL:Z99715 xref: HGNC:HGNC:22942 xref: UniGene:Hs.156369 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059282 ! TENN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020232 name: TNR_human def: "Tenascin-R precursor gene" [UniProtKB:Q92752] xref: EMBL:X98085 xref: EMBL:Z67996 xref: EMBL:Z94055 xref: EMBL:Z94057 xref: HGNC:HGNC:11953 xref: UniGene:Hs.537792 xref: UniGene:Hs.659864 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058089 ! TENR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020233 name: TNXB_human def: "Tenascin-X precursor gene" [UniProtKB:P22105] synonym: "HXBL" EXACT [UniProtKB:P22105] synonym: "TNX" EXACT [UniProtKB:P22105] synonym: "TNXB1" EXACT [UniProtKB:P22105] synonym: "TNXB2" EXACT [UniProtKB:P22105] synonym: "XB" EXACT [UniProtKB:P22105] xref: EMBL:AB209012 xref: EMBL:AF019413 xref: EMBL:AL049547 xref: EMBL:AL645922 xref: EMBL:AL662828 xref: EMBL:AL662849 xref: EMBL:AL662884 xref: EMBL:AL772248 xref: EMBL:BC033740 xref: EMBL:BC125114 xref: EMBL:BC125115 xref: EMBL:BC130037 xref: EMBL:CH471081 xref: EMBL:CR753803 xref: EMBL:CR753845 xref: EMBL:CR759792 xref: EMBL:CR925796 xref: EMBL:CR936882 xref: EMBL:CR936924 xref: EMBL:M25813 xref: EMBL:U24488 xref: EMBL:U52696 xref: EMBL:U89337 xref: EMBL:X71923 xref: EMBL:Y13782 xref: EMBL:Y13783 xref: HGNC:HGNC:11976 xref: UniGene:Hs.42853 xref: UniGene:Hs.485104 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054187 ! B0UYX3_HUMAN relationship: codes_for CCO:B0054188 ! B0V046_HUMAN relationship: codes_for CCO:B0055141 ! TENX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020234 name: TERT_human def: "Telomerase reverse transcriptase gene" [UniProtKB:O14746] synonym: "EST2" EXACT [UniProtKB:O14746] synonym: "TCS1" EXACT [UniProtKB:O14746] synonym: "TRT" EXACT [UniProtKB:O14746] xref: EMBL:AB085628 xref: EMBL:AB086379 xref: EMBL:AF015950 xref: EMBL:AF018167 xref: EMBL:AF128893 xref: EMBL:AF128894 xref: EMBL:AY007685 xref: EMBL:DQ264729 xref: HGNC:HGNC:11730 xref: UniGene:Hs.492203 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054372 ! TERT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020235 name: TEX2_human def: "Testis-expressed sequence 2 protein gene" [UniProtKB:Q8IWB9] synonym: "KIAA1738" EXACT [UniProtKB:Q8IWB9] xref: EMBL:AB051525 xref: EMBL:AL834251 xref: EMBL:BC040521 xref: EMBL:CR627433 xref: HGNC:HGNC:30884 xref: UniGene:Hs.175414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057358 ! TEX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020236 name: GTF2A1_human def: "Transcription initiation factor IIA subunit 1 gene" [UniProtKB:P52655] synonym: "TF2A1" EXACT [UniProtKB:P52655] xref: EMBL:AC010582 xref: EMBL:BC107155 xref: EMBL:BC107156 xref: EMBL:D14886 xref: EMBL:D14887 xref: EMBL:X75383 xref: EMBL:X77225 xref: HGNC:HGNC:4646 xref: UniGene:Hs.592334 xref: UniGene:Hs.593630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055488 ! TF2AA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020237 name: GTF2A1L_human def: "TFIIA-alpha and beta-like factor gene" [UniProtKB:Q9UNN4] synonym: "ALF" EXACT [UniProtKB:Q9UNN4] synonym: "GTF2A1LF" EXACT [UniProtKB:Q9UNN4] xref: EMBL:AF026169 xref: EMBL:AF106857 xref: EMBL:BC025991 xref: HGNC:HGNC:30727 xref: UniGene:Hs.44385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059253 ! TF2AY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020238 name: GTF2B_human def: "Transcription initiation factor IIB gene" [UniProtKB:Q00403] synonym: "TF2B" EXACT [UniProtKB:Q00403] synonym: "TFIIB" EXACT [UniProtKB:Q00403] xref: EMBL:AL445991 xref: EMBL:BC020597 xref: EMBL:BC021000 xref: EMBL:M76766 xref: EMBL:S44184 xref: EMBL:X59268 xref: HGNC:HGNC:4648 xref: UniGene:Hs.481852 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022444 ! TF2B_HUMAN relationship: codes_for CCO:B0054269 ! B1APE1_HUMAN relationship: codes_for CCO:B0054270 ! B1APE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020239 name: GTF2H5_human def: "General transcription factor IIH subunit 5 gene" [UniProtKB:Q6ZYL4] synonym: "C6orf175" EXACT [UniProtKB:Q6ZYL4] synonym: "TTDA" EXACT [UniProtKB:Q6ZYL4] xref: EMBL:AJ634743 xref: EMBL:AL590703 xref: EMBL:BC056906 xref: EMBL:BC060317 xref: HGNC:HGNC:21157 xref: UniGene:Hs.356224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057091 ! TF2H5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020240 name: TFCP2L1_human def: "Transcription factor CP2-like protein 1 gene" [UniProtKB:Q9NZI6] synonym: "CRTR1" EXACT [UniProtKB:Q9NZI6] synonym: "LBP9" EXACT [UniProtKB:Q9NZI6] xref: EMBL:AC013399 xref: EMBL:AC079988 xref: EMBL:AF198488 xref: EMBL:BC064698 xref: HGNC:HGNC:17925 xref: UniGene:Hs.156471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058998 ! TF2L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020241 name: TGIF2LX_human def: "Homeobox protein TGIF2LX gene" [UniProtKB:Q8IUE1] synonym: "TGIFLX" EXACT [UniProtKB:Q8IUE1] xref: EMBL:AF497480 xref: EMBL:AJ427749 xref: EMBL:AL590041 xref: EMBL:BC101144 xref: EMBL:BC101145 xref: EMBL:BC117398 xref: EMBL:BC117400 xref: HGNC:HGNC:18569 xref: HGNC:HGNC:18570 xref: UniGene:Hs.592220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021241 ! TF2LX_HUMAN relationship: codes_for CCO:B0021248 ! Q3ZCM9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020242 name: TGIF2LY_human def: "Homeobox protein TGIF2LY gene" [UniProtKB:Q8IUE0] synonym: "TGIFLY" EXACT [UniProtKB:Q8IUE0] xref: EMBL:AF332223 xref: EMBL:AJ427750 xref: HGNC:HGNC:18569 xref: UniGene:Hs.112148 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021260 ! TF2LY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020243 name: GTF3A_human def: "Transcription factor IIIA gene" [UniProtKB:Q92664] xref: EMBL:D32257 xref: EMBL:U14134 xref: EMBL:U20272 xref: HGNC:HGNC:4662 xref: UniGene:Hs.445977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058079 ! TF3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020244 name: TFAM_human def: "Transcription factor A, mitochondrial precursor gene" [UniProtKB:Q00059] synonym: "TCF6L2" EXACT [UniProtKB:Q00059] xref: EMBL:AC023170 xref: EMBL:BC126366 xref: EMBL:BT019658 xref: EMBL:BT019659 xref: EMBL:M62810 xref: EMBL:X64269 xref: HGNC:HGNC:11741 xref: UniGene:Hs.642966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054002 ! A8MRB2_HUMAN relationship: codes_for CCO:B0055678 ! TFAM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020245 name: TFAP4_human def: "Transcription factor AP-4 gene" [UniProtKB:Q01664] xref: EMBL:AC004653 xref: EMBL:BC010576 xref: EMBL:S73885 xref: EMBL:X57435 xref: HGNC:HGNC:11745 xref: UniGene:Hs.513305 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055693 ! TFAP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020246 name: TFB1M_human def: "Dimethyladenosine transferase 1, mitochondrial precursor gene" [UniProtKB:Q8WVM0] synonym: "CGI-75" EXACT [UniProtKB:Q8WVM0] xref: EMBL:AF151833 xref: EMBL:AL139101 xref: EMBL:BC005183 xref: EMBL:BC017788 xref: HGNC:HGNC:17037 xref: UniGene:Hs.279908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057995 ! TFB1M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020247 name: TFB2M_human def: "Dimethyladenosine transferase 2, mitochondrial precursor gene" [UniProtKB:Q9H5Q4] synonym: "NS5ATP5" EXACT [UniProtKB:Q9H5Q4] xref: EMBL:AF529366 xref: EMBL:AK026314 xref: EMBL:AK026835 xref: EMBL:AL356583 xref: EMBL:BC003383 xref: HGNC:HGNC:18559 xref: UniGene:Hs.7395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058728 ! TFB2M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020248 name: TFCP2_human def: "Alpha-globin transcription factor CP2 gene" [UniProtKB:Q12800] synonym: "LSF" EXACT [UniProtKB:Q12800] synonym: "SEF" EXACT [UniProtKB:Q12800] xref: EMBL:BC003634 xref: EMBL:U03494 xref: EMBL:U03495 xref: HGNC:HGNC:11748 xref: UniGene:Hs.699156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055842 ! TFCP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020249 name: TFEC_human def: "Transcription factor EC gene" [UniProtKB:O14948] synonym: "TCFEC" EXACT [UniProtKB:O14948] synonym: "TFECL" EXACT [UniProtKB:O14948] xref: EMBL:AJ608795 xref: EMBL:BC029891 xref: EMBL:CH236947 xref: EMBL:CH471070 xref: EMBL:CR933605 xref: EMBL:D43945 xref: HGNC:HGNC:11754 xref: UniGene:Hs.125962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054393 ! TFEC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020250 name: TNFAIP8_human def: "Tumor necrosis factor, alpha-induced protein 8 gene" [UniProtKB:O95379] xref: EMBL:AF070671 xref: EMBL:AF098933 xref: EMBL:AF099935 xref: EMBL:AF099936 xref: EMBL:BC005352 xref: EMBL:BC007014 xref: EMBL:CR457137 xref: HGNC:HGNC:17260 xref: UniGene:Hs.656274 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054753 ! TFIP8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020251 name: THAP7_human def: "THAP domain-containing protein 7 gene" [UniProtKB:Q9BT49] xref: EMBL:BC004346 xref: EMBL:CR456343 xref: HGNC:HGNC:23190 xref: UniGene:Hs.512756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058511 ! THAP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020252 name: THRA_human def: "Thyroid hormone receptor alpha gene" [UniProtKB:P10827] synonym: "ERBA1" EXACT [UniProtKB:P10827] synonym: "NR1A1" EXACT [UniProtKB:P10827] synonym: "THRA1" EXACT [UniProtKB:P10827] synonym: "THRA2" EXACT [UniProtKB:P10827] xref: EMBL:AF522368 xref: EMBL:BC000261 xref: EMBL:BC002728 xref: EMBL:BC035137 xref: EMBL:J03239 xref: EMBL:M24748 xref: EMBL:M24899 xref: EMBL:M24900 xref: EMBL:X55004 xref: EMBL:X55005 xref: EMBL:X55066 xref: EMBL:X55068 xref: EMBL:X55069 xref: EMBL:X55070 xref: EMBL:X55071 xref: EMBL:X55073 xref: EMBL:X55074 xref: EMBL:Y00479 xref: HGNC:HGNC:11796 xref: UniGene:Hs.724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054978 ! THA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020253 name: THRB_human def: "Thyroid hormone receptor beta gene" [UniProtKB:P10828] synonym: "ERBA2" EXACT [UniProtKB:P10828] synonym: "NR1A2" EXACT [UniProtKB:P10828] synonym: "THR1" EXACT [UniProtKB:P10828] xref: EMBL:AY286465 xref: EMBL:AY286466 xref: EMBL:AY286467 xref: EMBL:AY286468 xref: EMBL:AY286469 xref: EMBL:AY286470 xref: EMBL:AY286471 xref: EMBL:BC106929 xref: EMBL:BC106930 xref: EMBL:M26747 xref: EMBL:X04707 xref: EMBL:X74497 xref: HGNC:HGNC:11799 xref: UniGene:Hs.187861 xref: UniGene:Hs.610189 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054979 ! THB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020254 name: THEX1_human def: "Histone mRNA 3'-exonuclease 1 gene" [UniProtKB:Q8IV48] synonym: "3'EXO" EXACT [UniProtKB:Q8IV48] synonym: "ERI1" EXACT [UniProtKB:Q8IV48] xref: EMBL:AL137679 xref: EMBL:AY310909 xref: EMBL:BC035279 xref: HGNC:HGNC:23994 xref: UniGene:Hs.20000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057336 ! THEX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020255 name: THOC1_human def: "THO complex subunit 1 gene" [UniProtKB:Q96FV9] synonym: "HPR1" EXACT [UniProtKB:Q96FV9] xref: EMBL:BC010381 xref: EMBL:L36529 xref: HGNC:HGNC:19070 xref: UniGene:Hs.699172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058211 ! THOC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020256 name: THY1_human def: "Thy-1 membrane glycoprotein precursor gene" [UniProtKB:P04216] xref: EMBL:AF261093 xref: EMBL:AL161958 xref: EMBL:BC065559 xref: EMBL:M11749 xref: EMBL:S59749 xref: HGNC:HGNC:11801 xref: UniGene:Hs.653181 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054889 ! THY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020257 name: TG_human def: "Thyroglobulin precursor gene" [UniProtKB:P01266] xref: EMBL:AF080472 xref: EMBL:AF080473 xref: EMBL:AF080474 xref: EMBL:AF080475 xref: EMBL:AF080476 xref: EMBL:AF080477 xref: EMBL:AF080478 xref: EMBL:AF080479 xref: EMBL:AF080480 xref: EMBL:AF080481 xref: EMBL:AF080482 xref: EMBL:AF080483 xref: EMBL:AF080484 xref: EMBL:AF105681 xref: EMBL:AF105682 xref: EMBL:AF105683 xref: EMBL:AF105684 xref: EMBL:AF105685 xref: EMBL:AF105686 xref: EMBL:AF105687 xref: EMBL:AF169654 xref: EMBL:AF169655 xref: EMBL:AF169656 xref: EMBL:AF169657 xref: EMBL:AF169658 xref: EMBL:AF169659 xref: EMBL:AF169661 xref: EMBL:AF169662 xref: EMBL:AF169663 xref: EMBL:AF169664 xref: EMBL:AF170486 xref: EMBL:AF170487 xref: EMBL:AF170488 xref: EMBL:AF170489 xref: EMBL:AF230666 xref: EMBL:AF230667 xref: EMBL:AF235100 xref: EMBL:AF305872 xref: EMBL:S40807 xref: EMBL:U93033 xref: EMBL:X02154 xref: EMBL:X02749 xref: EMBL:X05615 xref: EMBL:X06059 xref: EMBL:X06060 xref: EMBL:X06061 xref: EMBL:X06062 xref: EMBL:X06063 xref: EMBL:X06064 xref: EMBL:X06065 xref: EMBL:X06066 xref: EMBL:X06067 xref: EMBL:X06068 xref: EMBL:X06069 xref: EMBL:X06070 xref: HGNC:HGNC:11764 xref: UniGene:Hs.654591 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054846 ! THYG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020258 name: TIA1_human def: "Nucleolysin TIA-1 isoform p40 gene" [UniProtKB:P31483] xref: EMBL:AC016700 xref: EMBL:CH471053 xref: EMBL:M77142 xref: EMBL:S70114 xref: HGNC:HGNC:11802 xref: UniGene:Hs.516075 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055244 ! TIA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020259 name: TIAF1_human def: "TGFB1-induced anti-apoptotic factor 1 gene" [UniProtKB:O95411] xref: EMBL:AF105277 xref: EMBL:BC047669 xref: EMBL:BC058075 xref: HGNC:HGNC:11803 xref: UniGene:Hs.462590 xref: UniGene:Hs.705495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054761 ! TIAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020260 name: TIAM1_human def: "T-lymphoma invasion and metastasis-inducing protein 1 gene" [UniProtKB:Q13009] xref: EMBL:AP000246 xref: EMBL:AP000247 xref: EMBL:BC117192 xref: EMBL:BC117196 xref: EMBL:U16296 xref: HGNC:HGNC:11805 xref: UniGene:Hs.517228 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055865 ! TIAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020261 name: TIAM2_human def: "T-lymphoma invasion and metastasis-inducing protein 2 gene" [UniProtKB:Q8IVF5] synonym: "KIAA2016" EXACT [UniProtKB:Q8IVF5] synonym: "STEF" EXACT [UniProtKB:Q8IVF5] xref: EMBL:AB095936 xref: EMBL:AF120323 xref: EMBL:AF120324 xref: EMBL:AK125459 xref: EMBL:AL122086 xref: EMBL:BC066979 xref: EMBL:CH471051 xref: HGNC:HGNC:11806 xref: UniGene:Hs.586279 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057343 ! TIAM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020262 name: TIAL1_human def: "Nucleolysin TIAR gene" [UniProtKB:Q01085] xref: EMBL:M96954 xref: HGNC:HGNC:11804 xref: UniGene:Hs.701975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055684 ! TIAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020263 name: TIE1_human def: "Tyrosine-protein kinase receptor Tie-1 precursor gene" [UniProtKB:P35590] synonym: "TIE" EXACT [UniProtKB:P35590] xref: EMBL:BC038239 xref: EMBL:X60957 xref: HGNC:HGNC:11809 xref: UniGene:Hs.78824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055295 ! TIE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020264 name: TEK_human def: "Angiopoietin-1 receptor precursor gene" [UniProtKB:Q02763] synonym: "TIE2" EXACT [UniProtKB:Q02763] xref: EMBL:L06139 xref: HGNC:HGNC:11724 xref: UniGene:Hs.89640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055715 ! TIE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020265 name: RARRES1_human def: "Retinoic acid receptor responder protein 1 gene" [UniProtKB:P49788] synonym: "TIG1" EXACT [UniProtKB:P49788] xref: EMBL:BC029640 xref: EMBL:U27185 xref: HGNC:HGNC:9867 xref: UniGene:Hs.131269 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055437 ! TIG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020266 name: TIGD1_human def: "Tigger transposable element-derived protein 1 gene" [UniProtKB:Q96MW7] xref: EMBL:AC092165 xref: EMBL:AK056329 xref: EMBL:BC035143 xref: EMBL:BC063500 xref: HGNC:HGNC:14523 xref: UniGene:Hs.211823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058295 ! TIGD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020267 name: TIGD2_human def: "Tigger transposable element-derived protein 2 gene" [UniProtKB:Q4W5G0] xref: EMBL:AC104785 xref: HGNC:HGNC:18333 xref: UniGene:Hs.58924 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056335 ! TIGD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020268 name: TIGD4_human def: "Tigger transposable element-derived protein 4 gene" [UniProtKB:Q8IY51] xref: EMBL:AK058054 xref: EMBL:BC037869 xref: HGNC:HGNC:18335 xref: UniGene:Hs.301243 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057383 ! TIGD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020269 name: TIGD5_human def: "Tigger transposable element-derived protein 5 gene" [UniProtKB:Q53EQ6] xref: EMBL:AK027832 xref: EMBL:AK223583 xref: EMBL:BC032632 xref: HGNC:HGNC:18336 xref: UniGene:Hs.71574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056348 ! TIGD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020270 name: TIGD6_human def: "Tigger transposable element-derived protein 6 gene" [UniProtKB:Q17RP2] xref: EMBL:AK056604 xref: EMBL:AL136539 xref: EMBL:BC117249 xref: EMBL:CR533559 xref: HGNC:HGNC:18332 xref: UniGene:Hs.169333 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056185 ! TIGD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020271 name: TIGD7_human def: "Tigger transposable element-derived protein 7 gene" [UniProtKB:Q6NT04] xref: EMBL:AF251050 xref: EMBL:BC069623 xref: EMBL:BC069632 xref: HGNC:HGNC:18331 xref: UniGene:Hs.161287 xref: UniGene:Hs.699848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056856 ! TIGD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020272 name: TIMP1_human def: "Metalloproteinase inhibitor 1 precursor gene" [UniProtKB:P01033] synonym: "CLGI" EXACT [UniProtKB:P01033] synonym: "TIMP" EXACT [UniProtKB:P01033] xref: EMBL:BC000866 xref: EMBL:D11139 xref: EMBL:L47361 xref: EMBL:M12670 xref: EMBL:M59906 xref: EMBL:S68252 xref: EMBL:X02598 xref: EMBL:X03124 xref: HGNC:HGNC:11820 xref: UniGene:Hs.522632 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054831 ! TIMP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020273 name: TIMP2_human def: "Metalloproteinase inhibitor 2 precursor gene" [UniProtKB:P16035] xref: EMBL:BC052605 xref: EMBL:BC071586 xref: EMBL:J05593 xref: EMBL:M32304 xref: EMBL:S48568 xref: EMBL:S68860 xref: EMBL:U44381 xref: EMBL:U44382 xref: EMBL:U44383 xref: EMBL:U44385 xref: EMBL:X54533 xref: HGNC:HGNC:11821 xref: UniGene:Hs.633514 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055046 ! TIMP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020274 name: TIMP3_human def: "Metalloproteinase inhibitor 3 precursor gene" [UniProtKB:P35625] xref: EMBL:AL023282 xref: EMBL:BC014277 xref: EMBL:BT006848 xref: EMBL:CR456593 xref: EMBL:L15078 xref: EMBL:S78453 xref: EMBL:U02571 xref: EMBL:U14394 xref: EMBL:U33110 xref: EMBL:U33111 xref: EMBL:U33112 xref: EMBL:U33113 xref: EMBL:U33114 xref: EMBL:U38952 xref: EMBL:U38953 xref: EMBL:U38954 xref: EMBL:U38955 xref: EMBL:U67195 xref: EMBL:X76227 xref: EMBL:Z30183 xref: EMBL:Z98256 xref: HGNC:HGNC:11822 xref: UniGene:Hs.682316 xref: UniGene:Hs.701968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055297 ! TIMP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020275 name: PTH2_human def: "Tuberoinfundibular peptide of 39 residues precursor gene" [UniProtKB:Q96A98] synonym: "TIP39" EXACT [UniProtKB:Q96A98] synonym: "TIPF39" EXACT [UniProtKB:Q96A98] xref: EMBL:AY037555 xref: EMBL:AY048588 xref: EMBL:BC093995 xref: EMBL:BC093997 xref: HGNC:HGNC:30828 xref: UniGene:Hs.339845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058148 ! TIP39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020276 name: TIRAP_human def: "Toll/interleukin-1 receptor domain-containing adapter protein gene" [UniProtKB:P58753] synonym: "MAL" EXACT [UniProtKB:P58753] xref: EMBL:AF378129 xref: EMBL:AF406652 xref: EMBL:AF410783 xref: EMBL:AY282416 xref: EMBL:BC032474 xref: HGNC:HGNC:17192 xref: UniGene:Hs.537126 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055572 ! TIRAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020277 name: ZFP36L2_human def: "Butyrate response factor 2 gene" [UniProtKB:P47974] synonym: "BRF2" EXACT [UniProtKB:P47974] synonym: "ERF2" EXACT [UniProtKB:P47974] synonym: "RNF162C" EXACT [UniProtKB:P47974] synonym: "TIS11D" EXACT [UniProtKB:P47974] xref: EMBL:BC005010 xref: EMBL:U07802 xref: EMBL:X78992 xref: HGNC:HGNC:1108 xref: UniGene:Hs.503093 xref: UniGene:Hs.645068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019963 ! TISD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020278 name: TAC1_human def: "Protachykinin-1 precursor gene" [UniProtKB:P20366] synonym: "NKA" EXACT [UniProtKB:P20366] synonym: "NKNA" EXACT [UniProtKB:P20366] synonym: "TAC2" EXACT [UniProtKB:P20366] xref: EMBL:AF050655 xref: EMBL:AF050656 xref: EMBL:AF050658 xref: EMBL:AK222957 xref: EMBL:BC018047 xref: EMBL:M68906 xref: EMBL:M68907 xref: EMBL:U37529 xref: EMBL:X54469 xref: HGNC:HGNC:11517 xref: UniGene:Hs.2563 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055119 ! TKN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020279 name: TLR3_human def: "Toll-like receptor 3 precursor gene" [UniProtKB:O15455] xref: EMBL:U88879 xref: HGNC:HGNC:11849 xref: UniGene:Hs.657724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054438 ! TLR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020280 name: TLR4_human def: "Toll-like receptor 4 precursor gene" [UniProtKB:O00206] xref: EMBL:AB445638 xref: EMBL:AF172169 xref: EMBL:AF172170 xref: EMBL:AF172171 xref: EMBL:AF177765 xref: EMBL:AF177766 xref: EMBL:AK290053 xref: EMBL:AK293068 xref: EMBL:AK303730 xref: EMBL:AL160272 xref: EMBL:BC117422 xref: EMBL:CH471090 xref: EMBL:EF535831 xref: EMBL:EF535832 xref: EMBL:EF535833 xref: EMBL:U88880 xref: EMBL:U93091 xref: HGNC:HGNC:11850 xref: UniGene:Hs.174312 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022071 ! TLR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020281 name: TLR5_human def: "Toll-like receptor 5 precursor gene" [UniProtKB:O60602] synonym: "TIL3" EXACT [UniProtKB:O60602] xref: EMBL:AB060695 xref: EMBL:AF051151 xref: EMBL:AL929091 xref: EMBL:BC109118 xref: EMBL:U88881 xref: HGNC:HGNC:11851 xref: UniGene:Hs.604542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054569 ! TLR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020282 name: TLR7_human def: "Toll-like receptor 7 precursor gene" [UniProtKB:Q9NYK1] synonym: "UNQ248/PRO285" EXACT [UniProtKB:Q9NYK1] xref: EMBL:AF240467 xref: EMBL:AF245702 xref: EMBL:AY358292 xref: EMBL:BC033651 xref: HGNC:HGNC:15631 xref: UniGene:Hs.659215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058964 ! TLR7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020283 name: TLR8_human def: "Toll-like receptor 8 precursor gene" [UniProtKB:Q9NR97] synonym: "UNQ249/PRO286" EXACT [UniProtKB:Q9NR97] xref: EMBL:AF245703 xref: EMBL:AF246971 xref: EMBL:AY358296 xref: EMBL:BC101075 xref: EMBL:BC101076 xref: EMBL:BC101077 xref: HGNC:HGNC:15632 xref: UniGene:Hs.660543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056295 ! Q495P6_HUMAN relationship: codes_for CCO:B0058892 ! TLR8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020284 name: TLR9_human def: "Toll-like receptor 9 precursor gene" [UniProtKB:Q9NR96] synonym: "UNQ5798/PRO19605" EXACT [UniProtKB:Q9NR96] xref: EMBL:AB045180 xref: EMBL:AF245704 xref: EMBL:AF246972 xref: EMBL:AF246973 xref: EMBL:AF246974 xref: EMBL:AF259262 xref: EMBL:AF259263 xref: EMBL:AY359085 xref: EMBL:BC032713 xref: HGNC:HGNC:15633 xref: UniGene:Hs.87968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058891 ! TLR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020285 name: TLX1_human def: "T-cell leukemia homeobox protein 1 gene" [UniProtKB:P31314] synonym: "HOX11" EXACT [UniProtKB:P31314] synonym: "TCL3" EXACT [UniProtKB:P31314] xref: EMBL:AF067443 xref: EMBL:AJ009794 xref: EMBL:AL357395 xref: EMBL:CH471066 xref: EMBL:M62626 xref: EMBL:M75952 xref: EMBL:S38742 xref: HGNC:HGNC:5056 xref: UniGene:Hs.89583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055243 ! TLX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020286 name: TLX2_human def: "T-cell leukemia homeobox protein 2 gene" [UniProtKB:O43763] synonym: "HOX11L1" EXACT [UniProtKB:O43763] synonym: "NCX" EXACT [UniProtKB:O43763] xref: EMBL:AB008501 xref: EMBL:AJ002607 xref: EMBL:AJ002608 xref: EMBL:AJ002609 xref: EMBL:BC006356 xref: HGNC:HGNC:5057 xref: UniGene:Hs.168586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054519 ! TLX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020287 name: TLX3_human def: "T-cell leukemia homeobox protein 3 gene" [UniProtKB:O43711] synonym: "HOX11L2" EXACT [UniProtKB:O43711] xref: EMBL:AJ223798 xref: EMBL:AJ223799 xref: EMBL:AJ223800 xref: EMBL:BC017291 xref: HGNC:HGNC:13532 xref: UniGene:Hs.249125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054512 ! TLX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020288 name: TMEM101_human def: "Transmembrane protein 101 gene" [UniProtKB:Q96IK0] xref: EMBL:AB097008 xref: EMBL:BC007438 xref: HGNC:HGNC:28653 xref: UniGene:Hs.514211 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058229 ! TM101_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020289 name: TMED1_human def: "Transmembrane emp24 domain-containing protein 1 precursor gene" [UniProtKB:Q13445] synonym: "IL1RL1L" EXACT [UniProtKB:Q13445] synonym: "IL1RL1LG" EXACT [UniProtKB:Q13445] xref: EMBL:AC007229 xref: EMBL:BC002443 xref: EMBL:U41804 xref: HGNC:HGNC:17291 xref: UniGene:Hs.515139 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055909 ! TMED1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020290 name: TMEM11_human def: "Transmembrane protein 11 gene" [UniProtKB:P17152] synonym: "C17orf35" EXACT [UniProtKB:P17152] synonym: "PM1" EXACT [UniProtKB:P17152] xref: EMBL:AK311965 xref: EMBL:BC002819 xref: EMBL:BC005268 xref: EMBL:BC020815 xref: EMBL:BT006768 xref: EMBL:CH471210 xref: EMBL:X51804 xref: HGNC:HGNC:16823 xref: UniGene:Hs.654713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055084 ! TMM11_HUMAN relationship: codes_for CCO:B0063500 ! Q53YB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020291 name: TMEM97_human def: "Transmembrane protein 97 gene" [UniProtKB:Q5BJF2] synonym: "MAC30" EXACT [UniProtKB:Q5BJF2] xref: EMBL:BC091504 xref: EMBL:L19183 xref: HGNC:HGNC:28106 xref: UniGene:Hs.199695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056418 ! TMM97_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020292 name: TMEM9B_human def: "Transmembrane protein 9B precursor gene" [UniProtKB:Q9NQ34] synonym: "C11orf15" EXACT [UniProtKB:Q9NQ34] synonym: "UNQ712/PRO1375" EXACT [UniProtKB:Q9NQ34] xref: EMBL:AJ400877 xref: EMBL:AY359069 xref: EMBL:BC040124 xref: HGNC:HGNC:1168 xref: UniGene:Hs.501853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058861 ! TMM9B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020293 name: TMOD2_human def: "Tropomodulin-2 gene" [UniProtKB:Q9NZR1] synonym: "NTMOD" EXACT [UniProtKB:Q9NZR1] xref: EMBL:AF177169 xref: EMBL:BC064961 xref: HGNC:HGNC:11872 xref: UniGene:Hs.659839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059012 ! TMOD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020294 name: TNFSF13B_human def: "Tumor necrosis factor ligand superfamily member 13B gene" [UniProtKB:Q9Y275] synonym: "BAFF" EXACT [UniProtKB:Q9Y275] synonym: "BLYS" EXACT [UniProtKB:Q9Y275] synonym: "TALL1" EXACT [UniProtKB:Q9Y275] synonym: "TNFSF20" EXACT [UniProtKB:Q9Y275] synonym: "UNQ401/PRO738" EXACT [UniProtKB:Q9Y275] synonym: "ZTNF4" EXACT [UniProtKB:Q9Y275] xref: EMBL:AB073225 xref: EMBL:AF116456 xref: EMBL:AF132600 xref: EMBL:AF134715 xref: EMBL:AF136293 xref: EMBL:AF186114 xref: EMBL:AY358881 xref: EMBL:BC020674 xref: HGNC:HGNC:11929 xref: UniGene:Hs.525157 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059296 ! TN13B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020295 name: TNFAIP1_human def: "BTB/POZ domain-containing protein TNFAIP1 gene" [UniProtKB:Q13829] synonym: "EDP1" EXACT [UniProtKB:Q13829] xref: EMBL:AY065346 xref: EMBL:BC001643 xref: EMBL:BC001949 xref: EMBL:CR456819 xref: EMBL:M80783 xref: HGNC:HGNC:11894 xref: UniGene:Hs.76090 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055946 ! TNAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020296 name: TNFAIP3_human def: "Tumor necrosis factor, alpha-induced protein 3 gene" [UniProtKB:P21580] xref: EMBL:AL157444 xref: EMBL:AL357060 xref: EMBL:AY248754 xref: EMBL:BC113871 xref: EMBL:BC114480 xref: EMBL:M59465 xref: HGNC:HGNC:11896 xref: UniGene:Hs.591338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055134 ! TNAP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020297 name: TNFSF10_human def: "Tumor necrosis factor ligand superfamily member 10 gene" [UniProtKB:P50591] synonym: "APO2L" EXACT [UniProtKB:P50591] synonym: "TRAIL" EXACT [UniProtKB:P50591] xref: EMBL:BC032722 xref: EMBL:U37518 xref: EMBL:U57059 xref: HGNC:HGNC:11925 xref: UniGene:Hs.478275 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055455 ! TNF10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020298 name: TNFSF11_human def: "Tumor necrosis factor ligand superfamily member 11 gene" [UniProtKB:O14788] synonym: "OPGL" EXACT [UniProtKB:O14788] synonym: "RANKL" EXACT [UniProtKB:O14788] synonym: "TRANCE" EXACT [UniProtKB:O14788] xref: EMBL:AB037599 xref: EMBL:AB061227 xref: EMBL:AB064269 xref: EMBL:AB064270 xref: EMBL:AF013171 xref: EMBL:AF019047 xref: EMBL:AF053712 xref: EMBL:BC074823 xref: EMBL:BC074890 xref: HGNC:HGNC:11926 xref: UniGene:Hs.333791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054375 ! TNF11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020299 name: TNFSF12_human def: "Tumor necrosis factor ligand superfamily member 12 gene" [UniProtKB:O43508] synonym: "APO3L" EXACT [UniProtKB:O43508] synonym: "DR3LG" EXACT [UniProtKB:O43508] synonym: "UNQ181/PRO207" EXACT [UniProtKB:O43508] xref: EMBL:AF030099 xref: EMBL:AF055872 xref: EMBL:AY358870 xref: EMBL:BC019047 xref: HGNC:HGNC:11927 xref: UniGene:Hs.54673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054484 ! TNF12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020300 name: TNFSF13_human def: "Tumor necrosis factor ligand superfamily member 13 precursor gene" [UniProtKB:O75888] synonym: "APRIL" EXACT [UniProtKB:O75888] synonym: "TALL2" EXACT [UniProtKB:O75888] synonym: "UNQ383/PRO715" EXACT [UniProtKB:O75888] synonym: "ZTNF2" EXACT [UniProtKB:O75888] xref: EMBL:AF046888 xref: EMBL:AF114011 xref: EMBL:AF114012 xref: EMBL:AF114013 xref: EMBL:AF136294 xref: EMBL:AF184972 xref: EMBL:AY358880 xref: EMBL:BC008042 xref: EMBL:BT019561 xref: HGNC:HGNC:11928 xref: UniGene:Hs.54673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054674 ! TNF13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020301 name: TNFSF14_human def: "Tumor necrosis factor ligand superfamily member 14 gene" [UniProtKB:O43557] synonym: "HVEML" EXACT [UniProtKB:O43557] synonym: "LIGHT" EXACT [UniProtKB:O43557] synonym: "UNQ391/PRO726" EXACT [UniProtKB:O43557] xref: EMBL:AF036581 xref: EMBL:AF064090 xref: EMBL:AY028261 xref: EMBL:AY358812 xref: HGNC:HGNC:11930 xref: UniGene:Hs.129708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054490 ! TNF14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020302 name: LTB_human def: "Lymphotoxin-beta gene" [UniProtKB:Q06643] synonym: "TNFC" EXACT [UniProtKB:Q06643] synonym: "TNFSF3" EXACT [UniProtKB:Q06643] xref: EMBL:AF129756 xref: EMBL:AY070219 xref: EMBL:AY216497 xref: EMBL:BA000025 xref: EMBL:BC069330 xref: EMBL:L11015 xref: EMBL:L11016 xref: EMBL:U79029 xref: EMBL:U89922 xref: EMBL:Y14768 xref: HGNC:HGNC:6711 xref: UniGene:Hs.376208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055770 ! TNFC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020303 name: TNFSF4_human def: "Tumor necrosis factor ligand superfamily member 4 gene" [UniProtKB:P23510] synonym: "TXGP1" EXACT [UniProtKB:P23510] xref: EMBL:AB042988 xref: EMBL:AL022310 xref: EMBL:D90224 xref: EMBL:X79929 xref: HGNC:HGNC:11934 xref: UniGene:Hs.181097 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055160 ! TNFL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020304 name: FASLG_human def: "Tumor necrosis factor ligand superfamily member 6 gene" [UniProtKB:P48023] synonym: "APT1LG1" EXACT [UniProtKB:P48023] synonym: "FASL" EXACT [UniProtKB:P48023] synonym: "TNFSF6" EXACT [UniProtKB:P48023] xref: EMBL:AB013303 xref: EMBL:AF288573 xref: EMBL:BC017502 xref: EMBL:D38122 xref: EMBL:U08137 xref: EMBL:U11821 xref: EMBL:X89102 xref: EMBL:Z96050 xref: HGNC:HGNC:11936 xref: UniGene:Hs.2007 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055398 ! TNFL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020305 name: TNFSF8_human def: "Tumor necrosis factor ligand superfamily member 8 gene" [UniProtKB:P32971] synonym: "CD30L" EXACT [UniProtKB:P32971] synonym: "CD30LG" EXACT [UniProtKB:P32971] xref: EMBL:AF006381 xref: EMBL:AF006382 xref: EMBL:AF006383 xref: EMBL:AF006384 xref: EMBL:L09753 xref: HGNC:HGNC:11938 xref: UniGene:Hs.654445 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055263 ! TNFL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020306 name: TNFSF9_human def: "Tumor necrosis factor ligand superfamily member 9 gene" [UniProtKB:P41273] xref: EMBL:BC104805 xref: EMBL:BC104807 xref: EMBL:U03398 xref: HGNC:HGNC:11939 xref: UniGene:Hs.1524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055340 ! TNFL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020307 name: TNKS_human def: "Tankyrase-1 gene" [UniProtKB:O95271] synonym: "PARP5A" EXACT [UniProtKB:O95271] synonym: "PARPL" EXACT [UniProtKB:O95271] synonym: "TIN1" EXACT [UniProtKB:O95271] synonym: "TINF1" EXACT [UniProtKB:O95271] synonym: "TNKS1" EXACT [UniProtKB:O95271] xref: EMBL:AF082556 xref: EMBL:AF082557 xref: EMBL:AF082558 xref: EMBL:AF082559 xref: HGNC:HGNC:11941 xref: UniGene:Hs.370267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054745 ! TNKS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020308 name: TNNC1_human def: "Troponin C, slow skeletal and cardiac muscles gene" [UniProtKB:P63316] synonym: "TNNC" EXACT [UniProtKB:P63316] xref: EMBL:AF020769 xref: EMBL:BC030244 xref: EMBL:M37984 xref: EMBL:X07897 xref: HGNC:HGNC:11943 xref: UniGene:Hs.118845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055634 ! TNNC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020309 name: TNNI2_human def: "Troponin I, fast skeletal muscle gene" [UniProtKB:P48788] xref: EMBL:AC051649 xref: EMBL:AJ245761 xref: EMBL:BC032148 xref: EMBL:L21715 xref: HGNC:HGNC:11946 xref: UniGene:Hs.523403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055412 ! TNNI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020310 name: TNFRSF11A_human def: "Tumor necrosis factor receptor superfamily member 11A precursor gene" [UniProtKB:Q9Y6Q6] synonym: "RANK" EXACT [UniProtKB:Q9Y6Q6] xref: EMBL:AF018253 xref: HGNC:HGNC:11908 xref: UniGene:Hs.204044 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059413 ! TNR11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020311 name: TNFRSF12A_human def: "Tumor necrosis factor receptor superfamily member 12A precursor gene" [UniProtKB:Q9NP84] synonym: "FN14" EXACT [UniProtKB:Q9NP84] xref: EMBL:AB035480 xref: EMBL:AB035481 xref: EMBL:AF191148 xref: EMBL:BC002718 xref: HGNC:HGNC:18152 xref: UniGene:Hs.355899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058838 ! TNR12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020312 name: NGFR_human def: "Tumor necrosis factor receptor superfamily member 16 precursor gene" [UniProtKB:P08138] synonym: "TNFRSF16" EXACT [UniProtKB:P08138] xref: EMBL:BC050309 xref: EMBL:M14764 xref: EMBL:M21621 xref: HGNC:HGNC:7809 xref: UniGene:Hs.415768 xref: UniGene:Hs.681726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054921 ! TNR16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020313 name: TNFRSF17_human def: "Tumor necrosis factor receptor superfamily member 17 gene" [UniProtKB:Q02223] synonym: "BCM" EXACT [UniProtKB:Q02223] synonym: "BCMA" EXACT [UniProtKB:Q02223] xref: EMBL:AB052772 xref: EMBL:AC007216 xref: EMBL:AY509112 xref: EMBL:U95742 xref: EMBL:Z14954 xref: EMBL:Z29574 xref: EMBL:Z29575 xref: HGNC:HGNC:11913 xref: UniGene:Hs.2556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055707 ! TNR17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020314 name: TNFRSF18_human def: "Tumor necrosis factor receptor superfamily member 18 precursor gene" [UniProtKB:Q9Y5U5] synonym: "AITR" EXACT [UniProtKB:Q9Y5U5] synonym: "GITR" EXACT [UniProtKB:Q9Y5U5] synonym: "UNQ319/PRO364" EXACT [UniProtKB:Q9Y5U5] xref: EMBL:AF117297 xref: EMBL:AF125304 xref: EMBL:AF241229 xref: EMBL:AY358877 xref: EMBL:BT019532 xref: HGNC:HGNC:11914 xref: UniGene:Hs.212680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059387 ! TNR18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020315 name: TNFRSF19_human def: "Tumor necrosis factor receptor superfamily member 19 precursor gene" [UniProtKB:Q9NS68] synonym: "TAJ" EXACT [UniProtKB:Q9NS68] synonym: "TROY" EXACT [UniProtKB:Q9NS68] synonym: "UNQ1888/PRO4333" EXACT [UniProtKB:Q9NS68] xref: EMBL:AB040434 xref: EMBL:AF167555 xref: EMBL:AF246998 xref: EMBL:AF246999 xref: EMBL:AY358888 xref: EMBL:BC047321 xref: HGNC:HGNC:11915 xref: UniGene:Hs.149168 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058911 ! TNR19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020316 name: TNFRSF21_human def: "Tumor necrosis factor receptor superfamily member 21 precursor gene" [UniProtKB:O75509] synonym: "DR6" EXACT [UniProtKB:O75509] synonym: "UNQ437/PRO868" EXACT [UniProtKB:O75509] xref: EMBL:AF068868 xref: EMBL:AL096801 xref: EMBL:AY358304 xref: EMBL:BC010241 xref: EMBL:BC017730 xref: EMBL:BC021572 xref: EMBL:BT007420 xref: HGNC:HGNC:13469 xref: UniGene:Hs.443577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054647 ! TNR21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020317 name: TNFRSF25_human def: "Tumor necrosis factor receptor superfamily member 25 precursor gene" [UniProtKB:Q93038] synonym: "APO3" EXACT [UniProtKB:Q93038] synonym: "DDR3" EXACT [UniProtKB:Q93038] synonym: "DR3" EXACT [UniProtKB:Q93038] synonym: "TNFRSF12" EXACT [UniProtKB:Q93038] synonym: "UNQ455/PRO779" EXACT [UniProtKB:Q93038] synonym: "WSL" EXACT [UniProtKB:Q93038] synonym: "WSL1" EXACT [UniProtKB:Q93038] xref: EMBL:AB051850 xref: EMBL:AB051851 xref: EMBL:AF026070 xref: EMBL:AF026071 xref: EMBL:AL158217 xref: EMBL:AY254324 xref: EMBL:AY358309 xref: EMBL:U72763 xref: EMBL:U74611 xref: EMBL:U75380 xref: EMBL:U75381 xref: EMBL:U78029 xref: EMBL:U83597 xref: EMBL:U83598 xref: EMBL:U83599 xref: EMBL:U83600 xref: EMBL:U94501 xref: EMBL:U94502 xref: EMBL:U94503 xref: EMBL:U94504 xref: EMBL:U94505 xref: EMBL:U94506 xref: EMBL:U94507 xref: EMBL:U94508 xref: EMBL:U94509 xref: EMBL:U94510 xref: EMBL:U94512 xref: EMBL:Y09392 xref: HGNC:HGNC:11910 xref: UniGene:Hs.462529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054247 ! B1ALX0_HUMAN relationship: codes_for CCO:B0058121 ! TNR25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020318 name: EDA2R_human def: "Tumor necrosis factor receptor superfamily member 27 gene" [UniProtKB:Q9HAV5] synonym: "TNFRSF27" EXACT [UniProtKB:Q9HAV5] synonym: "UNQ2448/PRO5727/PRO34080" EXACT [UniProtKB:Q9HAV5] synonym: "XEDAR" EXACT [UniProtKB:Q9HAV5] xref: EMBL:AF298812 xref: EMBL:AL353136 xref: EMBL:AY152724 xref: EMBL:AY358735 xref: EMBL:AY358736 xref: EMBL:BC034919 xref: HGNC:HGNC:17756 xref: UniGene:Hs.302017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058770 ! TNR27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020319 name: LTBR_human def: "Tumor necrosis factor receptor superfamily member 3 precursor gene" [UniProtKB:P36941] synonym: "D12S370" EXACT [UniProtKB:P36941] synonym: "TNFCR" EXACT [UniProtKB:P36941] synonym: "TNFRSF3" EXACT [UniProtKB:P36941] xref: EMBL:BC026262 xref: EMBL:L04270 xref: HGNC:HGNC:6718 xref: UniGene:Hs.1116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055313 ! TNR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020320 name: CD40_human def: "Tumor necrosis factor receptor superfamily member 5 precursor gene" [UniProtKB:P25942] synonym: "TNFRSF5" EXACT [UniProtKB:P25942] xref: EMBL:AJ300189 xref: EMBL:AK222896 xref: EMBL:AL035662 xref: EMBL:AY225405 xref: EMBL:AY504960 xref: EMBL:BC012419 xref: EMBL:BC064518 xref: EMBL:BT019901 xref: EMBL:CH471077 xref: EMBL:EF064754 xref: EMBL:X60592 xref: HGNC:HGNC:11919 xref: UniGene:Hs.472860 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055188 ! TNR5_HUMAN relationship: codes_for CCO:B0056885 ! Q6P2H9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020321 name: TNFRSF6B_human def: "Tumor necrosis factor receptor superfamily member 6B precursor gene" [UniProtKB:O95407] synonym: "DCR3" EXACT [UniProtKB:O95407] synonym: "TR6" EXACT [UniProtKB:O95407] synonym: "UNQ186/PRO212" EXACT [UniProtKB:O95407] xref: EMBL:AF104419 xref: EMBL:AF134240 xref: EMBL:AF217793 xref: EMBL:AF217794 xref: EMBL:AF217796 xref: EMBL:AL121845 xref: EMBL:AY358279 xref: EMBL:BC017065 xref: EMBL:BC034349 xref: HGNC:HGNC:11921 xref: UniGene:Hs.434878 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054760 ! TNR6B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020322 name: TNFRSF9_human def: "Tumor necrosis factor receptor superfamily member 9 precursor gene" [UniProtKB:Q07011] synonym: "CD137" EXACT [UniProtKB:Q07011] synonym: "ILA" EXACT [UniProtKB:Q07011] xref: EMBL:AL009183 xref: EMBL:AY438976 xref: EMBL:BC006196 xref: EMBL:L12964 xref: EMBL:U03397 xref: HGNC:HGNC:11924 xref: UniGene:Hs.654459 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055780 ! TNR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020323 name: TOB1_human def: "Protein Tob1 gene" [UniProtKB:P50616] synonym: "TOB" EXACT [UniProtKB:P50616] synonym: "TROB1" EXACT [UniProtKB:P50616] xref: EMBL:BC031406 xref: EMBL:BC070493 xref: EMBL:BC098415 xref: EMBL:BT019380 xref: EMBL:BT019381 xref: EMBL:CR536487 xref: EMBL:CR541686 xref: EMBL:D38305 xref: HGNC:HGNC:11979 xref: UniGene:Hs.531550 xref: UniGene:Hs.653129 xref: UniGene:Hs.702372 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025823 ! TOB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020324 name: TOP3B_human def: "DNA topoisomerase 3-beta-1 gene" [UniProtKB:O95985] synonym: "TOP3B1" EXACT [UniProtKB:O95985] xref: EMBL:AF017146 xref: EMBL:AF053082 xref: EMBL:AF125216 xref: EMBL:BC002432 xref: EMBL:CR456596 xref: EMBL:D87012 xref: HGNC:HGNC:11993 xref: UniGene:Hs.436401 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054815 ! TOP3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020325 name: TOX2_human def: "TOX high mobility group box family member 2 gene" [UniProtKB:Q96NM4] synonym: "C20orf100" EXACT [UniProtKB:Q96NM4] synonym: "GCX1" EXACT [UniProtKB:Q96NM4] xref: EMBL:AK055135 xref: EMBL:AL034419 xref: EMBL:AL121587 xref: EMBL:BC007636 xref: HGNC:HGNC:16095 xref: UniGene:Hs.26608 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058310 ! TOX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020326 name: TOX3_human def: "TOX high mobility group box family member 3 gene" [UniProtKB:O15405] synonym: "CAGF9" EXACT [UniProtKB:O15405] synonym: "TNRC9" EXACT [UniProtKB:O15405] xref: EMBL:AC007490 xref: EMBL:U80736 xref: HGNC:HGNC:11972 xref: UniGene:Hs.460789 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054435 ! TOX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020327 name: TOX4_human def: "TOX high mobility group box family member 4 gene" [UniProtKB:O94842] synonym: "C14orf92" EXACT [UniProtKB:O94842] synonym: "KIAA0737" EXACT [UniProtKB:O94842] xref: EMBL:AB018280 xref: EMBL:BC013689 xref: HGNC:HGNC:20161 xref: UniGene:Hs.555910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054703 ! TOX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020328 name: TOX_human def: "Thymocyte selection-associated high mobility group box protein TOX gene" [UniProtKB:O94900] synonym: "KIAA0808" EXACT [UniProtKB:O94900] xref: EMBL:AB018351 xref: EMBL:BC016665 xref: HGNC:HGNC:18988 xref: UniGene:Hs.491805 xref: UniGene:Hs.634856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054707 ! TOX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020329 name: MPL_human def: "Thrombopoietin receptor precursor gene" [UniProtKB:P40238] synonym: "TPOR" EXACT [UniProtKB:P40238] xref: EMBL:M90102 xref: EMBL:M90103 xref: EMBL:U68159 xref: EMBL:U68160 xref: EMBL:U68161 xref: EMBL:U68162 xref: HGNC:HGNC:7217 xref: UniGene:Hs.82906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055327 ! TPOR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020330 name: TRAPPC2_human def: "Trafficking protein particle complex subunit 2 gene" [UniProtKB:O14582] synonym: "SEDL" EXACT [UniProtKB:O14582] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054354 ! TPPC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020331 name: TRAPPC2P_human def: "Trafficking protein particle complex subunit 2 gene" [UniProtKB:O14582] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054354 ! TPPC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020332 name: TPPP_human def: "Tubulin polymerization-promoting protein gene" [UniProtKB:O94811] synonym: "TPPP1" EXACT [UniProtKB:O94811] xref: EMBL:AB017016 xref: EMBL:BC040496 xref: EMBL:BT020035 xref: HGNC:HGNC:24164 xref: UniGene:Hs.481466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054701 ! TPPP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020333 name: TPRX1_human def: "Tetra-peptide repeat homeobox protein 1 gene" [UniProtKB:Q8N7U7] xref: EMBL:AK097640 xref: EMBL:BC141863 xref: HGNC:HGNC:32174 xref: UniGene:Hs.629812 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057508 ! TPRX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020334 name: TPTE_human def: "Putative tyrosine-protein phosphatase TPTE gene" [UniProtKB:P56180] xref: EMBL:AF007118 xref: EMBL:AF495908 xref: EMBL:AL163201 xref: EMBL:AY219886 xref: EMBL:AY219887 xref: EMBL:AY219888 xref: EMBL:BC028719 xref: HGNC:HGNC:12023 xref: UniGene:Hs.122986 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055540 ! TPTE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020335 name: TNFRSF10A_human def: "Tumor necrosis factor receptor superfamily member 10A precursor gene" [UniProtKB:O00220] synonym: "APO2" EXACT [UniProtKB:O00220] synonym: "DR4" EXACT [UniProtKB:O00220] synonym: "TRAILR1" EXACT [UniProtKB:O00220] xref: EMBL:BC012866 xref: EMBL:U90875 xref: HGNC:HGNC:11904 xref: UniGene:Hs.591834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054301 ! TR10A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020336 name: TNFRSF10B_human def: "Tumor necrosis factor receptor superfamily member 10B precursor gene" [UniProtKB:O14763] synonym: "DR5" EXACT [UniProtKB:O14763] synonym: "KILLER" EXACT [UniProtKB:O14763] synonym: "TRAILR2" EXACT [UniProtKB:O14763] synonym: "TRICK2" EXACT [UniProtKB:O14763] synonym: "UNQ160/PRO186" EXACT [UniProtKB:O14763] synonym: "ZTNFR9" EXACT [UniProtKB:O14763] xref: EMBL:AB014718 xref: EMBL:AF012535 xref: EMBL:AF012628 xref: EMBL:AF016266 xref: EMBL:AF016268 xref: EMBL:AF016849 xref: EMBL:AF018657 xref: EMBL:AF018658 xref: EMBL:AF020501 xref: EMBL:AF022386 xref: EMBL:AF153687 xref: EMBL:AF192548 xref: EMBL:AY358277 xref: EMBL:BC001281 xref: HGNC:HGNC:11905 xref: UniGene:Hs.521456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054373 ! TR10B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020337 name: TNFRSF10D_human def: "Tumor necrosis factor receptor superfamily member 10D precursor gene" [UniProtKB:Q9UBN6] synonym: "DCR2" EXACT [UniProtKB:Q9UBN6] synonym: "TRAILR4" EXACT [UniProtKB:Q9UBN6] synonym: "TRUNDD" EXACT [UniProtKB:Q9UBN6] synonym: "UNQ251/PRO288" EXACT [UniProtKB:Q9UBN6] xref: EMBL:AF021232 xref: EMBL:AF021233 xref: EMBL:AF023849 xref: EMBL:AF029761 xref: EMBL:AY358285 xref: EMBL:BC052270 xref: HGNC:HGNC:11907 xref: UniGene:Hs.213467 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059079 ! TR10D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020338 name: TNFRSF11B_human def: "Tumor necrosis factor receptor superfamily member 11B precursor gene" [UniProtKB:O00300] synonym: "OCIF" EXACT [UniProtKB:O00300] synonym: "OPG" EXACT [UniProtKB:O00300] xref: EMBL:AB002146 xref: EMBL:AB008822 xref: EMBL:AF134187 xref: EMBL:AK223155 xref: EMBL:AY466112 xref: EMBL:BC030155 xref: EMBL:U94332 xref: HGNC:HGNC:11909 xref: UniGene:Hs.81791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054310 ! TR11B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020339 name: THRAP3_human def: "Thyroid hormone receptor-associated protein 3 gene" [UniProtKB:Q9Y2W1] synonym: "TRAP150" EXACT [UniProtKB:Q9Y2W1] xref: EMBL:AF117756 xref: EMBL:AL591845 xref: EMBL:BC037554 xref: EMBL:BC112330 xref: EMBL:BC112350 xref: HGNC:HGNC:22964 xref: UniGene:Hs.585396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059320 ! TR150_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020340 name: TRAF3_human def: "TNF receptor-associated factor 3 gene" [UniProtKB:Q13114] synonym: "CAP1" EXACT [UniProtKB:Q13114] synonym: "CRAF1" EXACT [UniProtKB:Q13114] xref: EMBL:AF110908 xref: EMBL:AL132801 xref: EMBL:BC075086 xref: EMBL:BC075087 xref: EMBL:BX247977 xref: EMBL:L38509 xref: EMBL:U15637 xref: EMBL:U19260 xref: EMBL:U21092 xref: HGNC:HGNC:12033 xref: UniGene:Hs.510528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053847 ! A6NHG8_HUMAN relationship: codes_for CCO:B0055874 ! TRAF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020341 name: TRAF4_human def: "TNF receptor-associated factor 4 gene" [UniProtKB:Q9BUZ4] synonym: "CART1" EXACT [UniProtKB:Q9BUZ4] synonym: "MLN62" EXACT [UniProtKB:Q9BUZ4] synonym: "RNF83" EXACT [UniProtKB:Q9BUZ4] xref: EMBL:AF082185 xref: EMBL:BC001769 xref: EMBL:DQ323999 xref: EMBL:X80200 xref: HGNC:HGNC:12034 xref: UniGene:Hs.8375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058525 ! TRAF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020342 name: TRAF5_human def: "TNF receptor-associated factor 5 gene" [UniProtKB:O00463] synonym: "RNF84" EXACT [UniProtKB:O00463] xref: EMBL:AB000509 xref: EMBL:BC029600 xref: EMBL:U69108 xref: HGNC:HGNC:12035 xref: UniGene:Hs.523930 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054323 ! TRAF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020343 name: TRAF7_human def: "E3 ubiquitin-protein ligase TRAF7 gene" [UniProtKB:Q6Q0C0] synonym: "RFWD1" EXACT [UniProtKB:Q6Q0C0] synonym: "RNF119" EXACT [UniProtKB:Q6Q0C0] xref: EMBL:AL136921 xref: EMBL:AY569455 xref: EMBL:BC024267 xref: HGNC:HGNC:20456 xref: UniGene:Hs.643537 xref: UniGene:Hs.705526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056926 ! TRAF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020344 name: TRAIP_human def: "TRAF-interacting protein gene" [UniProtKB:Q9BWF2] synonym: "RNF206" EXACT [UniProtKB:Q9BWF2] synonym: "TRIP" EXACT [UniProtKB:Q9BWF2] xref: EMBL:BC000310 xref: EMBL:BC019283 xref: EMBL:U77845 xref: HGNC:HGNC:30764 xref: UniGene:Hs.517972 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058532 ! TRAIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020345 name: TRAK1_human def: "Trafficking kinesin-binding protein 1 gene" [UniProtKB:Q9UPV9] synonym: "KIAA1042" EXACT [UniProtKB:Q9UPV9] synonym: "OIP106" EXACT [UniProtKB:Q9UPV9] xref: EMBL:AB028965 xref: EMBL:BC015922 xref: HGNC:HGNC:29947 xref: UniGene:Hs.535711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059269 ! TRAK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020346 name: TRAT1_human def: "T-cell receptor-associated transmembrane adapter 1 gene" [UniProtKB:Q6PIZ9] synonym: "HSPC062" EXACT [UniProtKB:Q6PIZ9] synonym: "TCRIM" EXACT [UniProtKB:Q6PIZ9] xref: EMBL:AF161547 xref: EMBL:BC025713 xref: HGNC:HGNC:30698 xref: UniGene:Hs.138701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056916 ! TRAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020347 name: TARBP2_human def: "TAR RNA-binding protein 2 gene" [UniProtKB:Q15633] synonym: "TRBP" EXACT [UniProtKB:Q15633] xref: EMBL:AF281068 xref: EMBL:BC005860 xref: EMBL:BT007140 xref: EMBL:CH471054 xref: EMBL:M60801 xref: EMBL:U08998 xref: HGNC:HGNC:11569 xref: UniGene:Hs.326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056086 ! TRBP2_HUMAN relationship: codes_for CCO:B0058037 ! Q8WY32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020348 name: TRERF1_human def: "Transcriptional-regulating factor 1 gene" [UniProtKB:Q96PN7] synonym: "BCAR2" EXACT [UniProtKB:Q96PN7] synonym: "RAPA" EXACT [UniProtKB:Q96PN7] synonym: "TREP132" EXACT [UniProtKB:Q96PN7] xref: EMBL:AF297872 xref: EMBL:AJ277275 xref: EMBL:AJ277276 xref: EMBL:AK002096 xref: EMBL:AL096814 xref: HGNC:HGNC:18273 xref: UniGene:Hs.485392 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058340 ! TREF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020349 name: TREM1_human def: "Triggering receptor expressed on myeloid cells 1 precursor gene" [UniProtKB:Q9NP99] xref: EMBL:AF196329 xref: EMBL:AF287008 xref: EMBL:AK223264 xref: EMBL:AL391903 xref: EMBL:AY074783 xref: EMBL:BC017773 xref: HGNC:HGNC:17760 xref: UniGene:Hs.283022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058842 ! TREM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020350 name: TF_human def: "Serotransferrin precursor gene" [UniProtKB:P02787] synonym: "PRO1400" EXACT [UniProtKB:P02787] xref: EMBL:AF058327 xref: EMBL:AF118063 xref: EMBL:AF288139 xref: EMBL:AF288140 xref: EMBL:AF288141 xref: EMBL:AF288142 xref: EMBL:AF288143 xref: EMBL:AF288144 xref: EMBL:AF294270 xref: EMBL:AF294271 xref: EMBL:AJ252279 xref: EMBL:AY308797 xref: EMBL:BC059367 xref: EMBL:M11361 xref: EMBL:M11362 xref: EMBL:M11363 xref: EMBL:M11364 xref: EMBL:M11365 xref: EMBL:M11366 xref: EMBL:M11367 xref: EMBL:M11368 xref: EMBL:M11369 xref: EMBL:M11370 xref: EMBL:M11371 xref: EMBL:M11372 xref: EMBL:M12525 xref: EMBL:M12530 xref: EMBL:M15673 xref: EMBL:M17610 xref: EMBL:M17611 xref: EMBL:M17612 xref: EMBL:M17613 xref: EMBL:M17614 xref: EMBL:M21569 xref: EMBL:M21570 xref: EMBL:M26641 xref: EMBL:S95936 xref: EMBL:U88581 xref: EMBL:X04600 xref: HGNC:HGNC:11740 xref: UniGene:Hs.518267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054876 ! TRFE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020351 name: TRHR_human def: "Thyrotropin-releasing hormone receptor gene" [UniProtKB:P34981] xref: EMBL:AJ011701 xref: EMBL:AY493373 xref: EMBL:BC105045 xref: EMBL:BC113360 xref: EMBL:D16845 xref: EMBL:D85376 xref: EMBL:S75281 xref: EMBL:S75283 xref: EMBL:X72089 xref: EMBL:X75071 xref: HGNC:HGNC:12299 xref: UniGene:Hs.3022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055274 ! TRFR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020352 name: TRHDE_human def: "Thyrotropin-releasing hormone-degrading ectoenzyme gene" [UniProtKB:Q9UKU6] synonym: "UNQ2507/PRO5995" EXACT [UniProtKB:Q9UKU6] xref: EMBL:AF126372 xref: EMBL:AY358765 xref: HGNC:HGNC:30748 xref: UniGene:Hs.199814 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059202 ! TRHDE_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020353 name: TRH_human def: "Prothyroliberin precursor gene" [UniProtKB:P20396] xref: EMBL:BC069375 xref: EMBL:BC074888 xref: EMBL:BC074889 xref: EMBL:BC110515 xref: EMBL:BC110516 xref: EMBL:M63581 xref: EMBL:M63582 xref: HGNC:HGNC:12298 xref: UniGene:Hs.182231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055122 ! TRH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020354 name: TRIM22_human def: "Tripartite motif-containing protein 22 gene" [UniProtKB:Q8IYM9] synonym: "RNF94" EXACT [UniProtKB:Q8IYM9] synonym: "STAF50" EXACT [UniProtKB:Q8IYM9] xref: EMBL:BC035582 xref: EMBL:X82200 xref: HGNC:HGNC:16379 xref: UniGene:Hs.501778 xref: UniGene:Hs.684559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057390 ! TRI22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020355 name: TRIM35_human def: "Tripartite motif-containing protein 35 gene" [UniProtKB:Q9UPQ4] synonym: "HLS5" EXACT [UniProtKB:Q9UPQ4] synonym: "KIAA1098" EXACT [UniProtKB:Q9UPQ4] xref: EMBL:AB029021 xref: EMBL:AF492463 xref: EMBL:BC018337 xref: EMBL:BC069226 xref: HGNC:HGNC:16285 xref: UniGene:Hs.104223 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059264 ! TRI35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020356 name: TRIM38_human def: "Tripartite motif-containing protein 38 gene" [UniProtKB:O00635] synonym: "RNF15" EXACT [UniProtKB:O00635] synonym: "RORET" EXACT [UniProtKB:O00635] xref: EMBL:BC026930 xref: EMBL:U90547 xref: EMBL:U91328 xref: HGNC:HGNC:10059 xref: UniGene:Hs.584851 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054339 ! TRI38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020357 name: TRIM54_human def: "Tripartite motif-containing protein 54 gene" [UniProtKB:Q9BYV2] synonym: "MURF" EXACT [UniProtKB:Q9BYV2] synonym: "MURF3" EXACT [UniProtKB:Q9BYV2] synonym: "RNF30" EXACT [UniProtKB:Q9BYV2] xref: EMBL:AC013413 xref: EMBL:AJ291714 xref: EMBL:BC141807 xref: EMBL:CH471053 xref: HGNC:HGNC:16008 xref: UniGene:Hs.516036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058583 ! TRI54_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020358 name: TRIM55_human def: "Tripartite motif-containing protein 55 gene" [UniProtKB:Q9BYV6] synonym: "MURF2" EXACT [UniProtKB:Q9BYV6] synonym: "RNF29" EXACT [UniProtKB:Q9BYV6] xref: EMBL:AJ243488 xref: EMBL:AJ243489 xref: EMBL:AJ277493 xref: EMBL:AJ291712 xref: EMBL:AJ431704 xref: EMBL:BC007750 xref: EMBL:BT007212 xref: HGNC:HGNC:14215 xref: UniGene:Hs.85524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058584 ! TRI55_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020359 name: TRIM63_human def: "E3 ubiquitin-protein ligase TRIM63 gene" [UniProtKB:Q969Q1] synonym: "IRF" EXACT [UniProtKB:Q969Q1] synonym: "MURF1" EXACT [UniProtKB:Q969Q1] synonym: "RNF28" EXACT [UniProtKB:Q969Q1] synonym: "SMRZ" EXACT [UniProtKB:Q969Q1] xref: EMBL:AF353673 xref: EMBL:AF361946 xref: EMBL:AJ276484 xref: EMBL:AJ291713 xref: EMBL:AK056942 xref: EMBL:AL391650 xref: EMBL:BC080529 xref: HGNC:HGNC:16007 xref: UniGene:Hs.279709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058137 ! TRI63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020360 name: TRIO_human def: "Triple functional domain protein gene" [UniProtKB:O75962] xref: EMBL:AB209754 xref: EMBL:AF091395 xref: EMBL:AK131423 xref: EMBL:BC017268 xref: EMBL:BC035585 xref: EMBL:U42390 xref: HGNC:HGNC:12303 xref: UniGene:Hs.130031 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054681 ! TRIO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020361 name: TRIP4_human def: "Activating signal cointegrator 1 gene" [UniProtKB:Q15650] xref: EMBL:AF168418 xref: EMBL:BC012448 xref: EMBL:L40371 xref: HGNC:HGNC:12310 xref: UniGene:Hs.500340 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056092 ! TRIP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020362 name: TRMT6_human def: "tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 gene" [UniProtKB:Q9UJA5] synonym: "CGI-09" EXACT [UniProtKB:Q9UJA5] synonym: "KIAA1153" EXACT [UniProtKB:Q9UJA5] synonym: "TRM6" EXACT [UniProtKB:Q9UJA5] xref: EMBL:AB032979 xref: EMBL:AF132943 xref: EMBL:AK000613 xref: EMBL:AL035461 xref: EMBL:BC001262 xref: HGNC:HGNC:20900 xref: UniGene:Hs.128791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059170 ! TRM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020363 name: TRPS1_human def: "Zinc finger transcription factor Trps1 gene" [UniProtKB:Q9UHF7] xref: EMBL:AF178030 xref: EMBL:AF183810 xref: EMBL:AF264784 xref: EMBL:AK000948 xref: HGNC:HGNC:12340 xref: UniGene:Hs.657018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059138 ! TRPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020364 name: TXNRD1_human def: "Thioredoxin reductase 1, cytoplasmic gene" [UniProtKB:Q16881] synonym: "KDRF" EXACT [UniProtKB:Q16881] xref: EMBL:AF077367 xref: EMBL:AF208018 xref: EMBL:AJ001050 xref: EMBL:AY057105 xref: EMBL:AY344081 xref: EMBL:AY344083 xref: EMBL:AY344084 xref: EMBL:AY344086 xref: EMBL:AY344087 xref: EMBL:AY344089 xref: EMBL:AY344092 xref: EMBL:AY344093 xref: EMBL:AY344095 xref: EMBL:AY344096 xref: EMBL:AY344670 xref: EMBL:AY344673 xref: EMBL:AY344679 xref: EMBL:BC018122 xref: EMBL:BT019640 xref: EMBL:CR536506 xref: EMBL:D88687 xref: EMBL:DQ157758 xref: EMBL:S79851 xref: EMBL:X91247 xref: HGNC:HGNC:12437 xref: UniGene:Hs.705447 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056179 ! TRXR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020365 name: TAS1R1_human def: "Taste receptor type 1 member 1 precursor gene" [UniProtKB:Q7RTX1] synonym: "GM148" EXACT [UniProtKB:Q7RTX1] synonym: "GPR70" EXACT [UniProtKB:Q7RTX1] synonym: "T1R1" EXACT [UniProtKB:Q7RTX1] synonym: "TR1" EXACT [UniProtKB:Q7RTX1] xref: EMBL:AB065618 xref: EMBL:AF387617 xref: EMBL:AF387618 xref: EMBL:AF387619 xref: EMBL:AF387620 xref: EMBL:AL591866 xref: EMBL:BK000153 xref: HGNC:HGNC:14448 xref: UniGene:Hs.124574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057140 ! TS1R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020366 name: TAS1R2_human def: "Taste receptor type 1 member 2 precursor gene" [UniProtKB:Q8TE23] synonym: "GPR71" EXACT [UniProtKB:Q8TE23] synonym: "T1R2" EXACT [UniProtKB:Q8TE23] synonym: "TR2" EXACT [UniProtKB:Q8TE23] xref: EMBL:AF458149 xref: EMBL:AF458150 xref: EMBL:AF458151 xref: EMBL:AF458152 xref: EMBL:AF458153 xref: EMBL:AF458154 xref: EMBL:AL831755 xref: EMBL:BK000151 xref: EMBL:BX537160 xref: HGNC:HGNC:14905 xref: UniGene:Hs.553548 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057950 ! TS1R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020367 name: TAS1R3_human def: "Taste receptor type 1 member 3 precursor gene" [UniProtKB:Q7RTX0] synonym: "T1R3" EXACT [UniProtKB:Q7RTX0] synonym: "TR3" EXACT [UniProtKB:Q7RTX0] xref: EMBL:AB065647 xref: EMBL:AL139287 xref: EMBL:BK000152 xref: HGNC:HGNC:15661 xref: UniGene:Hs.74375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057139 ! TS1R3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020368 name: TRSPAP1_human def: "tRNA selenocysteine-associated protein 1 gene" [UniProtKB:Q9NX07] synonym: "SECP43" EXACT [UniProtKB:Q9NX07] xref: EMBL:AK000510 xref: EMBL:AL513497 xref: EMBL:BC000680 xref: EMBL:BC039879 xref: EMBL:CH471059 xref: HGNC:HGNC:30813 xref: UniGene:Hs.533626 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029172 ! TSAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020369 name: TNFAIP6_human def: "Tumor necrosis factor-inducible gene 6 protein precursor gene" [UniProtKB:P98066] synonym: "TSG6" EXACT [UniProtKB:P98066] xref: EMBL:AJ419936 xref: EMBL:AJ421518 xref: EMBL:BC030205 xref: EMBL:M31165 xref: HGNC:HGNC:11898 xref: UniGene:Hs.437322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055666 ! TSG6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020370 name: TSHZ1_human def: "Teashirt homolog 1 gene" [UniProtKB:Q6ZSZ6] synonym: "SDCCAG33" EXACT [UniProtKB:Q6ZSZ6] synonym: "TSH1" EXACT [UniProtKB:Q6ZSZ6] xref: EMBL:AB210042 xref: EMBL:AF039698 xref: EMBL:AK127042 xref: EMBL:AK223545 xref: HGNC:HGNC:10669 xref: UniGene:Hs.284217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057061 ! TSH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020371 name: TSHZ3_human def: "Teashirt homolog 3 gene" [UniProtKB:Q63HK5] synonym: "KIAA1474" EXACT [UniProtKB:Q63HK5] synonym: "TSH3" EXACT [UniProtKB:Q63HK5] synonym: "ZNF537" EXACT [UniProtKB:Q63HK5] xref: EMBL:AB040907 xref: EMBL:AL136805 xref: EMBL:BX648745 xref: HGNC:HGNC:30700 xref: UniGene:Hs.278436 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056687 ! TSH3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020372 name: TSHB_human def: "Thyrotropin subunit beta precursor gene" [UniProtKB:P01222] xref: EMBL:BC069298 xref: EMBL:M21024 xref: EMBL:M23670 xref: EMBL:M23671 xref: EMBL:M25164 xref: EMBL:S70587 xref: EMBL:X02866 xref: EMBL:X02867 xref: HGNC:HGNC:12372 xref: UniGene:Hs.406687 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054838 ! TSHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020373 name: TSHR_human def: "Thyrotropin receptor precursor gene" [UniProtKB:P16473] synonym: "LGR3" EXACT [UniProtKB:P16473] xref: EMBL:AC007262 xref: EMBL:AC010072 xref: EMBL:AC010582 xref: EMBL:AL136040 xref: EMBL:AY429111 xref: EMBL:BC127628 xref: EMBL:M31774 xref: EMBL:M32215 xref: EMBL:M73747 xref: EMBL:S45272 xref: HGNC:HGNC:12373 xref: UniGene:Hs.160411 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053703 ! A0PJU7_HUMAN relationship: codes_for CCO:B0055054 ! TSHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020374 name: TSPAN31_human def: "Tetraspanin-31 gene" [UniProtKB:Q12999] synonym: "SAS" EXACT [UniProtKB:Q12999] xref: EMBL:BC010377 xref: EMBL:U01160 xref: EMBL:U81031 xref: HGNC:HGNC:10539 xref: UniGene:Hs.632708 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055864 ! TSN31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020375 name: TSPAN6_human def: "Tetraspanin-6 gene" [UniProtKB:O43657] synonym: "TM4SF6" EXACT [UniProtKB:O43657] synonym: "UNQ767/PRO1560" EXACT [UniProtKB:O43657] xref: EMBL:AF043906 xref: EMBL:AF053453 xref: EMBL:AF133426 xref: EMBL:AL035608 xref: EMBL:AY358825 xref: EMBL:BC012389 xref: EMBL:BT006977 xref: EMBL:U84895 xref: HGNC:HGNC:11858 xref: UniGene:Hs.43233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054508 ! TSN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020376 name: TSPO_human def: "Translocator protein gene" [UniProtKB:P30536] synonym: "BZRP" EXACT [UniProtKB:P30536] synonym: "MBR" EXACT [UniProtKB:P30536] xref: EMBL:AY383615 xref: EMBL:BC001110 xref: EMBL:M36035 xref: EMBL:U12421 xref: EMBL:Z82214 xref: HGNC:HGNC:1158 xref: UniGene:Hs.202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055220 ! TSPO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020377 name: TSPY1_human def: "Testis-specific Y-encoded protein 1 gene" [UniProtKB:Q01534] synonym: "TSPY" EXACT [UniProtKB:Q01534] xref: EMBL:AC006156 xref: EMBL:AC006158 xref: EMBL:AC025819 xref: EMBL:AF106331 xref: EMBL:BC121114 xref: EMBL:M94893 xref: EMBL:M98524 xref: EMBL:M98525 xref: EMBL:U58096 xref: EMBL:X06325 xref: EMBL:X74029 xref: HGNC:HGNC:12381 xref: UniGene:Hs.556121 xref: UniGene:Hs.571766 xref: UniGene:Hs.592352 xref: UniGene:Hs.646249 xref: UniGene:Hs.647493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055689 ! TSPY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020378 name: TSSK4_human def: "Testis-specific serine/threonine-protein kinase 4 gene" [UniProtKB:Q6SA08] synonym: "C14orf20" EXACT [UniProtKB:Q6SA08] synonym: "STK22E" EXACT [UniProtKB:Q6SA08] synonym: "TSSK5" EXACT [UniProtKB:Q6SA08] xref: EMBL:AK131042 xref: EMBL:AY461663 xref: EMBL:BC111088 xref: HGNC:HGNC:19825 xref: UniGene:Hs.314432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056940 ! TSSK4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020379 name: TTF2_human def: "Transcription termination factor 2 gene" [UniProtKB:Q9UNY4] xref: EMBL:AF073771 xref: EMBL:AF080255 xref: EMBL:AL391476 xref: EMBL:AL445231 xref: EMBL:BC030058 xref: HGNC:HGNC:12398 xref: UniGene:Hs.702424 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059256 ! TTF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020380 name: TTL_human def: "Tubulin--tyrosine ligase gene" [UniProtKB:Q8NG68] xref: EMBL:AB071393 xref: EMBL:BC036819 xref: EMBL:BX538316 xref: HGNC:HGNC:21586 xref: UniGene:Hs.358997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057614 ! TTL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020381 name: TTRAP_human def: "TRAF and TNF receptor-associated protein gene" [UniProtKB:O95551] synonym: "AD-022" EXACT [UniProtKB:O95551] synonym: "EAP2" EXACT [UniProtKB:O95551] xref: EMBL:AF201687 xref: EMBL:AF223469 xref: EMBL:AJ269473 xref: EMBL:AK002168 xref: EMBL:AL031775 xref: EMBL:AY613922 xref: EMBL:BC017553 xref: EMBL:BC110375 xref: HGNC:HGNC:17768 xref: UniGene:Hs.696104 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054771 ! TTRAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020382 name: TULP3_human def: "Tubby-related protein 3 gene" [UniProtKB:O75386] synonym: "TUBL3" EXACT [UniProtKB:O75386] xref: EMBL:AF045583 xref: EMBL:BC032587 xref: HGNC:HGNC:12425 xref: UniGene:Hs.655333 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054629 ! TULP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020383 name: TULP4_human def: "Tubby-related protein 4 gene" [UniProtKB:Q9NRJ4] synonym: "KIAA1397" EXACT [UniProtKB:Q9NRJ4] synonym: "TUBL4" EXACT [UniProtKB:Q9NRJ4] synonym: "TUSP" EXACT [UniProtKB:Q9NRJ4] xref: EMBL:AB037818 xref: EMBL:AF219946 xref: EMBL:AF288480 xref: EMBL:AL353800 xref: EMBL:AL360169 xref: EMBL:CH471051 xref: HGNC:HGNC:15530 xref: UniGene:Hs.486993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058900 ! TULP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020384 name: TWSG1_human def: "Twisted gastrulation protein homolog 1 precursor gene" [UniProtKB:Q9GZX9] synonym: "PSEC0250" EXACT [UniProtKB:Q9GZX9] synonym: "TSG" EXACT [UniProtKB:Q9GZX9] xref: EMBL:AF196834 xref: EMBL:AF294628 xref: EMBL:AJ297391 xref: EMBL:AK027629 xref: EMBL:AK075550 xref: EMBL:BC020490 xref: HGNC:HGNC:12429 xref: UniGene:Hs.514685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058643 ! TWSG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020385 name: TWIST1_human def: "Twist-related protein 1 gene" [UniProtKB:Q15672] synonym: "TWIST" EXACT [UniProtKB:Q15672] xref: EMBL:AC003986 xref: EMBL:BC036704 xref: EMBL:U80998 xref: EMBL:X91662 xref: EMBL:X99268 xref: EMBL:Y10871 xref: HGNC:HGNC:12428 xref: UniGene:Hs.644998 xref: UniGene:Hs.66744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053844 ! A6NH88_HUMAN relationship: codes_for CCO:B0056095 ! TWST1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020386 name: TWIST2_human def: "Twist-related protein 2 gene" [UniProtKB:Q8WVJ9] synonym: "DERMO1" EXACT [UniProtKB:Q8WVJ9] xref: EMBL:BC017907 xref: EMBL:BC033168 xref: EMBL:BC103755 xref: HGNC:HGNC:20670 xref: UniGene:Hs.422585 xref: UniGene:Hs.590904 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057994 ! TWST2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020387 name: TAX1BP3_human def: "Tax1-binding protein 3 gene" [UniProtKB:O14907] synonym: "TIP1" EXACT [UniProtKB:O14907] xref: EMBL:AF028823 xref: EMBL:AF168787 xref: EMBL:AF234997 xref: EMBL:AF277318 xref: EMBL:BC023980 xref: HGNC:HGNC:30684 xref: UniGene:Hs.12956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054390 ! TX1B3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020388 name: TXNDC17_human def: "Thioredoxin domain-containing protein 17 gene" [UniProtKB:Q9BRA2] synonym: "TXNL5" EXACT [UniProtKB:Q9BRA2] xref: EMBL:AJ344101 xref: EMBL:BC006405 xref: HGNC:HGNC:28218 xref: UniGene:Hs.408236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058488 ! TXD17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020389 name: TXLNA_human def: "Alpha-taxilin gene" [UniProtKB:P40222] synonym: "TXLN" EXACT [UniProtKB:P40222] xref: EMBL:AF516206 xref: EMBL:AL049795 xref: EMBL:AL832338 xref: EMBL:AL832636 xref: EMBL:AL832637 xref: EMBL:BC029686 xref: EMBL:BC046565 xref: EMBL:BC080578 xref: EMBL:BC103823 xref: EMBL:BC103824 xref: EMBL:L15344 xref: HGNC:HGNC:30685 xref: UniGene:Hs.699306 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055326 ! TXLNA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020390 name: TXNDC1_human def: "Thioredoxin domain-containing protein 1 precursor gene" [UniProtKB:Q9H3N1] synonym: "PSEC0085" EXACT [UniProtKB:Q9H3N1] synonym: "TMX" EXACT [UniProtKB:Q9H3N1] synonym: "TXNDC" EXACT [UniProtKB:Q9H3N1] synonym: "UNQ235/PRO268" EXACT [UniProtKB:Q9H3N1] xref: EMBL:AB048246 xref: EMBL:AK075395 xref: EMBL:AL080080 xref: EMBL:AL591807 xref: EMBL:AY358640 xref: EMBL:BC036460 xref: EMBL:BC056874 xref: HGNC:HGNC:15487 xref: UniGene:Hs.125221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058705 ! TXND1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020391 name: TXNDC4_human def: "Thioredoxin domain-containing protein 4 precursor gene" [UniProtKB:Q9BS26] synonym: "ERP44" EXACT [UniProtKB:Q9BS26] synonym: "KIAA0573" EXACT [UniProtKB:Q9BS26] synonym: "UNQ532/PRO1075" EXACT [UniProtKB:Q9BS26] xref: EMBL:AB011145 xref: EMBL:AJ344330 xref: EMBL:AK075024 xref: EMBL:AL137072 xref: EMBL:AL358937 xref: EMBL:AL360084 xref: EMBL:AY359048 xref: EMBL:BC005374 xref: HGNC:HGNC:18311 xref: UniGene:Hs.591899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058502 ! TXND4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020392 name: TXNDC5_human def: "Thioredoxin domain-containing protein 5 precursor gene" [UniProtKB:Q8NBS9] synonym: "TLP46" EXACT [UniProtKB:Q8NBS9] synonym: "UNQ364/PRO700" EXACT [UniProtKB:Q8NBS9] xref: EMBL:AJ440721 xref: EMBL:AK075291 xref: EMBL:AL133541 xref: EMBL:AL834423 xref: EMBL:AY358646 xref: EMBL:BC001199 xref: HGNC:HGNC:21073 xref: UniGene:Hs.150837 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057559 ! TXND5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020393 name: TMSL8_human def: "NB thymosin beta gene" [UniProtKB:Q99406] synonym: "TMSNB" EXACT [UniProtKB:Q99406] xref: EMBL:AL035609 xref: EMBL:BC000183 xref: EMBL:D82345 xref: HGNC:HGNC:30744 xref: UniGene:Hs.496530 xref: UniGene:Hs.56145 xref: UniGene:Hs.675540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058409 ! TYBN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020394 name: TYROBP_human def: "TYRO protein tyrosine kinase-binding protein precursor gene" [UniProtKB:O43914] synonym: "DAP12" EXACT [UniProtKB:O43914] synonym: "KARAP" EXACT [UniProtKB:O43914] xref: EMBL:AF019562 xref: EMBL:AF019563 xref: EMBL:AJ010098 xref: EMBL:AY074782 xref: EMBL:BC011175 xref: EMBL:BT009851 xref: EMBL:CR450342 xref: HGNC:HGNC:12449 xref: UniGene:Hs.515369 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054530 ! TYOBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020395 name: TYMP_human def: "Thymidine phosphorylase precursor gene" [UniProtKB:P19971] synonym: "ECGF1" EXACT [UniProtKB:P19971] xref: EMBL:BC018160 xref: EMBL:BC052211 xref: EMBL:M63193 xref: EMBL:U62317 xref: HGNC:HGNC:3148 xref: UniGene:Hs.592212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055112 ! TYPH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020396 name: TYRO3_human def: "Tyrosine-protein kinase receptor TYRO3 precursor gene" [UniProtKB:Q06418] synonym: "BYK" EXACT [UniProtKB:Q06418] synonym: "DTK" EXACT [UniProtKB:Q06418] synonym: "RSE" EXACT [UniProtKB:Q06418] synonym: "SKY" EXACT [UniProtKB:Q06418] xref: EMBL:BC049368 xref: EMBL:BC051756 xref: EMBL:D17517 xref: EMBL:D50479 xref: EMBL:U05682 xref: EMBL:U18934 xref: EMBL:X72886 xref: HGNC:HGNC:12446 xref: UniGene:Hs.381282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027493 ! TYRO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020397 name: TYMS_human def: "Thymidylate synthase gene" [UniProtKB:P04818] synonym: "OK/SW-cl.29" EXACT [UniProtKB:P04818] synonym: "TS" EXACT [UniProtKB:P04818] xref: EMBL:AB062290 xref: EMBL:BC002567 xref: EMBL:BC013919 xref: EMBL:BC083512 xref: EMBL:D00517 xref: EMBL:D00596 xref: EMBL:X02308 xref: HGNC:HGNC:12441 xref: UniGene:Hs.592338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054893 ! TYSY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020398 name: UBTF_human def: "Nucleolar transcription factor 1 gene" [UniProtKB:P17480] synonym: "UBF" EXACT [UniProtKB:P17480] synonym: "UBF1" EXACT [UniProtKB:P17480] xref: EMBL:BC042297 xref: EMBL:U65487 xref: EMBL:X53390 xref: EMBL:X53461 xref: EMBL:X56687 xref: HGNC:HGNC:12511 xref: UniGene:Hs.89781 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054292 ! O00164_HUMAN relationship: codes_for CCO:B0055088 ! UBF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020399 name: UBP1_human def: "Upstream-binding protein 1 gene" [UniProtKB:Q9NZI7] synonym: "LBP1" EXACT [UniProtKB:Q9NZI7] xref: EMBL:AF198487 xref: EMBL:AK023274 xref: EMBL:BC047235 xref: EMBL:CR749798 xref: HGNC:HGNC:12507 xref: UniGene:Hs.696578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058999 ! UBIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020400 name: UBN1_human def: "Ubinuclein gene" [UniProtKB:Q9NPG3] xref: EMBL:AF108454 xref: EMBL:AF108455 xref: EMBL:AF108456 xref: EMBL:AF108457 xref: EMBL:AF108458 xref: EMBL:AF108459 xref: EMBL:AF108460 xref: EMBL:AF108461 xref: EMBL:U19346 xref: HGNC:HGNC:12506 xref: UniGene:Hs.440219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058852 ! UBN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020401 name: USP6_human def: "Ubiquitin carboxyl-terminal hydrolase 6 gene" [UniProtKB:P35125] synonym: "HRP1" EXACT [UniProtKB:P35125] synonym: "TRE2" EXACT [UniProtKB:P35125] xref: EMBL:AY143550 xref: EMBL:AY163314 xref: EMBL:BC029495 xref: EMBL:X63546 xref: EMBL:X63547 xref: HGNC:HGNC:12629 xref: UniGene:Hs.448851 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055277 ! UBP6_HUMAN relationship: codes_for CCO:B0057573 ! Q8NCR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020402 name: UBR5_human def: "E3 ubiquitin-protein ligase UBR5 gene" [UniProtKB:O95071] synonym: "EDD" EXACT [UniProtKB:O95071] synonym: "EDD1" EXACT [UniProtKB:O95071] synonym: "HYD" EXACT [UniProtKB:O95071] synonym: "KIAA0896" EXACT [UniProtKB:O95071] xref: EMBL:AB020703 xref: EMBL:AF006010 xref: EMBL:U95000 xref: HGNC:HGNC:16806 xref: UniGene:Hs.591856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054719 ! UBR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020403 name: UCN_human def: "Urocortin precursor gene" [UniProtKB:P55089] xref: EMBL:AC013413 xref: EMBL:AF038633 xref: EMBL:BC104470 xref: EMBL:BC104471 xref: EMBL:CR542244 xref: HGNC:HGNC:12516 xref: UniGene:Hs.534363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055527 ! UCN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020404 name: UCN3_human def: "Urocortin-3 precursor gene" [UniProtKB:Q969E3] synonym: "SPC" EXACT [UniProtKB:Q969E3] xref: EMBL:AF361943 xref: EMBL:AY026949 xref: EMBL:BC069530 xref: EMBL:BC100868 xref: EMBL:BC100869 xref: EMBL:BC100870 xref: HGNC:HGNC:17781 xref: UniGene:Hs.511775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058126 ! UCN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020405 name: UIMC1_human def: "Ubiquitin interaction motif-containing protein 1 gene" [UniProtKB:Q96RL1] synonym: "RAP80" EXACT [UniProtKB:Q96RL1] synonym: "RXRIP110" EXACT [UniProtKB:Q96RL1] xref: EMBL:AF113538 xref: EMBL:AF284749 xref: EMBL:AF284753 xref: EMBL:AF349313 xref: EMBL:BC006078 xref: EMBL:BC032561 xref: EMBL:BX537376 xref: HGNC:HGNC:30298 xref: UniGene:Hs.232721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058381 ! UIMC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020406 name: ULK1_human def: "Serine/threonine-protein kinase ULK1 gene" [UniProtKB:O75385] synonym: "KIAA0722" EXACT [UniProtKB:O75385] xref: EMBL:AB018265 xref: EMBL:AF045458 xref: HGNC:HGNC:12558 xref: UniGene:Hs.47061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054628 ! ULK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020407 name: UNC13A_human def: "Protein unc-13 homolog A gene" [UniProtKB:Q9UPW8] synonym: "KIAA1032" EXACT [UniProtKB:Q9UPW8] xref: EMBL:AB028955 xref: EMBL:AK127106 xref: HGNC:HGNC:23150 xref: UniGene:Hs.164502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059271 ! UN13A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020408 name: UNC13B_human def: "Protein unc-13 homolog B gene" [UniProtKB:O14795] synonym: "UNC13" EXACT [UniProtKB:O14795] xref: EMBL:AF020202 xref: EMBL:AL160274 xref: EMBL:AL353795 xref: EMBL:AL354669 xref: EMBL:CH471071 xref: HGNC:HGNC:12566 xref: UniGene:Hs.493791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054250 ! B1AM27_HUMAN relationship: codes_for CCO:B0054377 ! UN13B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020409 name: UNC13C_human def: "Protein unc-13 homolog C gene" [UniProtKB:Q8NB66] xref: EMBL:AC010867 xref: EMBL:AC022302 xref: EMBL:AC034103 xref: EMBL:AC068711 xref: EMBL:AK054981 xref: EMBL:AK091491 xref: EMBL:AL834407 xref: EMBL:BC040740 xref: HGNC:HGNC:23149 xref: UniGene:Hs.657273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057556 ! UN13C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020410 name: UNC5CL_human def: "UNC5C-like protein gene" [UniProtKB:Q8IV45] synonym: "ZUD" EXACT [UniProtKB:Q8IV45] xref: EMBL:AL031778 xref: EMBL:AY510109 xref: EMBL:BC035284 xref: EMBL:CH471081 xref: HGNC:HGNC:21203 xref: UniGene:Hs.158357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057335 ! UN5CL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020411 name: UNCX_human def: "Homeobox protein unc-4 homolog gene" [UniProtKB:A6NJT0] synonym: "UNCX4.1" EXACT [UniProtKB:A6NJT0] xref: EMBL:AC073094 xref: EMBL:CH236953 xref: HGNC:HGNC:33194 xref: UniGene:Hs.232272 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053874 ! UNC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020412 name: UNC5A_human def: "Netrin receptor UNC5A precursor gene" [UniProtKB:Q6ZN44] synonym: "KIAA1976" EXACT [UniProtKB:Q6ZN44] synonym: "UNC5H1" EXACT [UniProtKB:Q6ZN44] xref: EMBL:AB075856 xref: EMBL:AK131380 xref: EMBL:BC009333 xref: EMBL:BC033727 xref: HGNC:HGNC:12567 xref: UniGene:Hs.33191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057010 ! UNC5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020413 name: UNC5B_human def: "Netrin receptor UNC5B precursor gene" [UniProtKB:Q8IZJ1] synonym: "P53RDL1" EXACT [UniProtKB:Q8IZJ1] synonym: "UNC5H2" EXACT [UniProtKB:Q8IZJ1] synonym: "UNQ1883/PRO4326" EXACT [UniProtKB:Q8IZJ1] xref: EMBL:AB096256 xref: EMBL:AK022859 xref: EMBL:AK094595 xref: EMBL:AY126437 xref: EMBL:AY358351 xref: HGNC:HGNC:12568 xref: UniGene:Hs.585457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057407 ! UNC5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020414 name: UNC5C_human def: "Netrin receptor UNC5C precursor gene" [UniProtKB:O95185] synonym: "UNC5H3" EXACT [UniProtKB:O95185] xref: EMBL:AF055634 xref: EMBL:BC041156 xref: HGNC:HGNC:12569 xref: UniGene:Hs.584831 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054733 ! UNC5C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020415 name: UNC5D_human def: "Netrin receptor UNC5D precursor gene" [UniProtKB:Q6UXZ4] synonym: "KIAA1777" EXACT [UniProtKB:Q6UXZ4] synonym: "UNC5H4" EXACT [UniProtKB:Q6UXZ4] synonym: "UNQ6012/PRO34692" EXACT [UniProtKB:Q6UXZ4] xref: EMBL:AB055056 xref: EMBL:AY358147 xref: HGNC:HGNC:18634 xref: UniGene:Hs.238889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056957 ! UNC5D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020416 name: PLAUR_human def: "Urokinase plasminogen activator surface receptor precursor gene" [UniProtKB:Q03405] synonym: "MO3" EXACT [UniProtKB:Q03405] synonym: "UPAR" EXACT [UniProtKB:Q03405] xref: EMBL:AC005525 xref: EMBL:AC006953 xref: EMBL:AF257789 xref: EMBL:AY029180 xref: EMBL:AY194849 xref: EMBL:BC002788 xref: EMBL:CR456952 xref: EMBL:M83246 xref: EMBL:S78532 xref: EMBL:U08839 xref: EMBL:U09346 xref: EMBL:U09347 xref: EMBL:U09931 xref: EMBL:U09932 xref: EMBL:U09933 xref: EMBL:U09935 xref: EMBL:U09936 xref: EMBL:U09937 xref: EMBL:X51675 xref: EMBL:X74039 xref: HGNC:HGNC:9053 xref: UniGene:Hs.466871 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055723 ! UPAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020417 name: UTS2R_human def: "Urotensin II receptor gene" [UniProtKB:Q9UKP6] synonym: "GPR14" EXACT [UniProtKB:Q9UKP6] xref: EMBL:AF140631 xref: HGNC:HGNC:4468 xref: UniGene:Hs.192720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059199 ! UR2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020418 name: PLAU_human def: "Urokinase-type plasminogen activator precursor gene" [UniProtKB:P00749] xref: EMBL:A18397 xref: EMBL:A21571 xref: EMBL:AF377330 xref: EMBL:BC013575 xref: EMBL:D00244 xref: EMBL:D11143 xref: EMBL:K02286 xref: EMBL:K03226 xref: EMBL:M15476 xref: EMBL:X02419 xref: EMBL:X02760 xref: HGNC:HGNC:9052 xref: UniGene:Hs.77274 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054827 ! UROK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020419 name: UMOD_human def: "Uromodulin precursor gene" [UniProtKB:P07911] xref: EMBL:AK127643 xref: EMBL:AY162963 xref: EMBL:AY162964 xref: EMBL:AY162965 xref: EMBL:AY162967 xref: EMBL:AY162968 xref: EMBL:AY162969 xref: EMBL:AY162970 xref: EMBL:BC035975 xref: EMBL:M15881 xref: EMBL:M17778 xref: HGNC:HGNC:12559 xref: UniGene:Hs.654425 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054917 ! UROM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020420 name: USP6NL_human def: "USP6 N-terminal-like protein gene" [UniProtKB:Q92738] synonym: "KIAA0019" EXACT [UniProtKB:Q92738] xref: EMBL:BC042943 xref: EMBL:D13644 xref: HGNC:HGNC:16858 xref: UniGene:Hs.498661 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058086 ! US6NL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020421 name: USF1_human def: "Upstream stimulatory factor 1 gene" [UniProtKB:P22415] synonym: "USF" EXACT [UniProtKB:P22415] xref: EMBL:AB017568 xref: EMBL:AL591806 xref: EMBL:AY593992 xref: EMBL:BC035505 xref: EMBL:CH471121 xref: EMBL:X55666 xref: HGNC:HGNC:12593 xref: UniGene:Hs.414880 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054277 ! B1AQP1_HUMAN relationship: codes_for CCO:B0055146 ! USF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020422 name: USF2_human def: "Upstream stimulatory factor 2 gene" [UniProtKB:Q15853] xref: EMBL:AD000684 xref: EMBL:AY147880 xref: EMBL:BC049821 xref: EMBL:CR536504 xref: EMBL:M77476 xref: EMBL:S50537 xref: EMBL:X90824 xref: EMBL:X90825 xref: EMBL:X90826 xref: EMBL:Y07661 xref: HGNC:HGNC:12594 xref: UniGene:Hs.454534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056117 ! USF2_HUMAN relationship: codes_for CCO:B0056975 ! Q6YI47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020423 name: USH2A_human def: "Usherin precursor gene" [UniProtKB:O75445] xref: EMBL:AC092799 xref: EMBL:AC093581 xref: EMBL:AC119429 xref: EMBL:AC138024 xref: EMBL:AF055580 xref: EMBL:AF091873 xref: EMBL:AF091874 xref: EMBL:AF091875 xref: EMBL:AF091876 xref: EMBL:AF091877 xref: EMBL:AF091878 xref: EMBL:AF091879 xref: EMBL:AF091880 xref: EMBL:AF091881 xref: EMBL:AF091882 xref: EMBL:AF091883 xref: EMBL:AF091884 xref: EMBL:AF091885 xref: EMBL:AF091886 xref: EMBL:AF091887 xref: EMBL:AF091888 xref: EMBL:AF091889 xref: EMBL:AL139259 xref: EMBL:AL358452 xref: EMBL:AL358858 xref: EMBL:AL445650 xref: EMBL:AL513305 xref: EMBL:AY481573 xref: HGNC:HGNC:12601 xref: UniGene:Hs.655974 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054636 ! USH2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020424 name: SCGB1A1_human def: "Uteroglobin precursor gene" [UniProtKB:P11684] synonym: "CC10" EXACT [UniProtKB:P11684] synonym: "CCSP" EXACT [UniProtKB:P11684] synonym: "UGB" EXACT [UniProtKB:P11684] xref: EMBL:BC004481 xref: EMBL:CR541780 xref: EMBL:U01101 xref: EMBL:U01102 xref: EMBL:X13197 xref: EMBL:X59875 xref: HGNC:HGNC:12523 xref: UniGene:Hs.523732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054993 ! UTER_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020425 name: UTF1_human def: "Undifferentiated embryonic cell transcription factor 1 gene" [UniProtKB:Q5T230] xref: EMBL:AB011076 xref: EMBL:AL445199 xref: EMBL:AY606112 xref: HGNC:HGNC:12634 xref: UniGene:Hs.458406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056565 ! UTF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020426 name: UTP11L_human def: "Probable U3 small nucleolar RNA-associated protein 11 gene" [UniProtKB:Q9Y3A2] synonym: "CGI-94" EXACT [UniProtKB:Q9Y3A2] synonym: "HDCMB12P" EXACT [UniProtKB:Q9Y3A2] xref: EMBL:AF067802 xref: EMBL:AF151852 xref: EMBL:AL603790 xref: EMBL:BC005182 xref: HGNC:HGNC:24329 xref: UniGene:Hs.472038 xref: UniGene:Hs.637686 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059334 ! UTP11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020427 name: UTP20_human def: "Small subunit processome component 20 homolog gene" [UniProtKB:O75691] synonym: "DRIM" EXACT [UniProtKB:O75691] xref: EMBL:AF072718 xref: EMBL:AJ006778 xref: HGNC:HGNC:17897 xref: UniGene:Hs.295732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054662 ! UTP20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020428 name: AVPR1A_human def: "Vasopressin V1a receptor gene" [UniProtKB:P37288] synonym: "AVPR1" EXACT [UniProtKB:P37288] xref: EMBL:AF030625 xref: EMBL:AF101725 xref: EMBL:AY322550 xref: EMBL:BC074803 xref: EMBL:BC074804 xref: EMBL:L25615 xref: EMBL:S73899 xref: EMBL:U19906 xref: HGNC:HGNC:895 xref: UniGene:Hs.2131 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055318 ! V1AR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020429 name: AVPR1B_human def: "Vasopressin V1b receptor gene" [UniProtKB:P47901] synonym: "AVPR3" EXACT [UniProtKB:P47901] synonym: "VPR3" EXACT [UniProtKB:P47901] xref: EMBL:AF030512 xref: EMBL:AF101726 xref: EMBL:AF152238 xref: EMBL:BX571818 xref: EMBL:D31833 xref: EMBL:DQ194816 xref: EMBL:L37112 xref: HGNC:HGNC:896 xref: UniGene:Hs.1372 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055395 ! V1BR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020430 name: AVPR2_human def: "Vasopressin V2 receptor gene" [UniProtKB:P30518] synonym: "ADHR" EXACT [UniProtKB:P30518] synonym: "DIR" EXACT [UniProtKB:P30518] synonym: "DIR3" EXACT [UniProtKB:P30518] synonym: "V2R" EXACT [UniProtKB:P30518] xref: EMBL:AF030626 xref: EMBL:AF032388 xref: EMBL:AF101727 xref: EMBL:AY242131 xref: EMBL:BC101484 xref: EMBL:BC112181 xref: EMBL:CH471172 xref: EMBL:L22206 xref: EMBL:U04357 xref: EMBL:Z11687 xref: HGNC:HGNC:897 xref: UniGene:Hs.567240 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054458 ! O43192_HUMAN relationship: codes_for CCO:B0055219 ! V2R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020431 name: VAC14_human def: "Protein VAC14 homolog gene" [UniProtKB:Q08AM6] synonym: "TAX1BP2" EXACT [UniProtKB:Q08AM6] synonym: "TRX" EXACT [UniProtKB:Q08AM6] xref: EMBL:AK025479 xref: EMBL:BC000536 xref: EMBL:BC007214 xref: EMBL:BC125108 xref: EMBL:BC125109 xref: EMBL:CR457343 xref: EMBL:U25801 xref: HGNC:HGNC:25507 xref: UniGene:Hs.445061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055799 ! VAC14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020432 name: VAPA_human def: "Vesicle-associated membrane protein-associated protein A gene" [UniProtKB:Q9P0L0] synonym: "VAP33" EXACT [UniProtKB:Q9P0L0] xref: EMBL:AF044670 xref: EMBL:AF057358 xref: EMBL:AF086627 xref: EMBL:AF154847 xref: EMBL:BC002992 xref: EMBL:BT019618 xref: HGNC:HGNC:12648 xref: UniGene:Hs.699980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059029 ! VAPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020433 name: VAPB_human def: "Vesicle-associated membrane protein-associated protein B/C gene" [UniProtKB:O95292] synonym: "UNQ484/PRO983" EXACT [UniProtKB:O95292] xref: EMBL:AF086628 xref: EMBL:AF086629 xref: EMBL:AF160212 xref: EMBL:AL035455 xref: EMBL:AY358464 xref: EMBL:BC001712 xref: HGNC:HGNC:12649 xref: UniGene:Hs.182625 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054746 ! VAPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020434 name: VAV2_human def: "Guanine nucleotide exchange factor VAV2 gene" [UniProtKB:P52735] xref: EMBL:AL357934 xref: EMBL:AL445931 xref: EMBL:AL590710 xref: EMBL:AY563001 xref: EMBL:BC033187 xref: EMBL:BC132965 xref: EMBL:BC132967 xref: EMBL:BX640754 xref: EMBL:CH471090 xref: EMBL:S76992 xref: HGNC:HGNC:12658 xref: UniGene:Hs.369921 xref: UniGene:Hs.678824 xref: UniGene:Hs.689325 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053885 ! A6NKJ3_HUMAN relationship: codes_for CCO:B0055489 ! VAV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020435 name: VAV3_human def: "Guanine nucleotide exchange factor VAV3 gene" [UniProtKB:Q9UKW4] xref: EMBL:AF067817 xref: EMBL:AF118886 xref: EMBL:AF118887 xref: HGNC:HGNC:12659 xref: UniGene:Hs.267659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059207 ! VAV3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020436 name: VAV1_human def: "Proto-oncogene vav gene" [UniProtKB:P15498] synonym: "VAV" EXACT [UniProtKB:P15498] xref: EMBL:AF030201 xref: EMBL:AF030202 xref: EMBL:AF030203 xref: EMBL:AF030204 xref: EMBL:AF030205 xref: EMBL:AF030206 xref: EMBL:AF030207 xref: EMBL:AF030208 xref: EMBL:AF030209 xref: EMBL:AF030210 xref: EMBL:AF030211 xref: EMBL:AF030212 xref: EMBL:AF030213 xref: EMBL:AF030214 xref: EMBL:AF030215 xref: EMBL:AF030216 xref: EMBL:AF030217 xref: EMBL:AF030218 xref: EMBL:AF030219 xref: EMBL:AF030220 xref: EMBL:AF030221 xref: EMBL:AF030222 xref: EMBL:AF030223 xref: EMBL:AF030224 xref: EMBL:AF030225 xref: EMBL:AF030226 xref: EMBL:AF030227 xref: EMBL:M59834 xref: EMBL:X16316 xref: EMBL:X83931 xref: HGNC:HGNC:12657 xref: UniGene:Hs.116237 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055037 ! VAV_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020437 name: VAX1_human def: "Ventral anterior homeobox 1 gene" [UniProtKB:Q5SQQ9] xref: EMBL:AK127095 xref: EMBL:AL731557 xref: EMBL:BC101694 xref: EMBL:BC101696 xref: HGNC:HGNC:12660 xref: UniGene:Hs.681703 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056534 ! VAX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020438 name: VAX2_human def: "Ventral anterior homeobox 2 gene" [UniProtKB:Q9UIW0] xref: EMBL:BC006336 xref: EMBL:Y17791 xref: HGNC:HGNC:12661 xref: UniGene:Hs.249170 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059166 ! VAX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020439 name: VCAM1_human def: "Vascular cell adhesion protein 1 precursor gene" [UniProtKB:P19320] synonym: "L1CAM" EXACT [UniProtKB:P19320] xref: EMBL:AF536818 xref: EMBL:BC017276 xref: EMBL:BC068490 xref: EMBL:BC085003 xref: EMBL:M30257 xref: EMBL:M60335 xref: EMBL:M73255 xref: EMBL:M92431 xref: EMBL:X53051 xref: HGNC:HGNC:12663 xref: UniGene:Hs.109225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055107 ! VCAM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020440 name: VDR_human def: "Vitamin D3 receptor gene" [UniProtKB:P11473] synonym: "NR1I1" EXACT [UniProtKB:P11473] xref: EMBL:AB002168 xref: EMBL:AF026260 xref: EMBL:AY342401 xref: EMBL:BC060832 xref: EMBL:J03258 xref: EMBL:M65208 xref: EMBL:X67482 xref: HGNC:HGNC:12679 xref: UniGene:Hs.524368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054992 ! VDR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020441 name: VENTX_human def: "Homeobox protein VENTX gene" [UniProtKB:O95231] synonym: "HPX42B" EXACT [UniProtKB:O95231] synonym: "VENTX2" EXACT [UniProtKB:O95231] xref: EMBL:AF068006 xref: EMBL:AF288039 xref: EMBL:AL445199 xref: EMBL:BC108915 xref: EMBL:BC108916 xref: HGNC:HGNC:13639 xref: UniGene:Hs.125231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054738 ! VENTX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020442 name: VEZF1_human def: "Vascular endothelial zinc finger 1 gene" [UniProtKB:Q14119] synonym: "DB1" EXACT [UniProtKB:Q14119] synonym: "ZNF161" EXACT [UniProtKB:Q14119] xref: EMBL:D28118 xref: HGNC:HGNC:12949 xref: UniGene:Hs.705368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055958 ! VEZF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020443 name: KDR_human def: "Vascular endothelial growth factor receptor 2 precursor gene" [UniProtKB:P35968] synonym: "FLK1" EXACT [UniProtKB:P35968] xref: EMBL:AF035121 xref: EMBL:AF063658 xref: EMBL:L04947 xref: EMBL:X61656 xref: EMBL:X89776 xref: HGNC:HGNC:6307 xref: UniGene:Hs.479756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055305 ! VGFR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020444 name: FLT4_human def: "Vascular endothelial growth factor receptor 3 precursor gene" [UniProtKB:P35916] xref: EMBL:U43143 xref: EMBL:X68203 xref: EMBL:X69878 xref: HGNC:HGNC:3767 xref: UniGene:Hs.646917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055304 ! VGFR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020445 name: VGLL1_human def: "Transcription cofactor vestigial-like protein 1 gene" [UniProtKB:Q99990] synonym: "TDU" EXACT [UniProtKB:Q99990] xref: EMBL:AC000115 xref: EMBL:AF137387 xref: EMBL:BC000045 xref: EMBL:BC003362 xref: EMBL:CH471150 xref: EMBL:Z97632 xref: HGNC:HGNC:20985 xref: UniGene:Hs.496843 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056434 ! Q5H914_HUMAN relationship: codes_for CCO:B0056435 ! Q5H915_HUMAN relationship: codes_for CCO:B0058467 ! VGLL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020446 name: VGLL2_human def: "Transcription cofactor vestigial-like protein 2 gene" [UniProtKB:Q8N8G2] synonym: "VITO1" EXACT [UniProtKB:Q8N8G2] xref: EMBL:AJ578053 xref: EMBL:AK096878 xref: EMBL:AY056583 xref: EMBL:BC069316 xref: EMBL:BC100798 xref: EMBL:BC100799 xref: EMBL:BC118545 xref: EMBL:BC118622 xref: EMBL:CH471051 xref: EMBL:Z98880 xref: HGNC:HGNC:20232 xref: UniGene:Hs.99324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057519 ! VGLL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020447 name: VGLL3_human def: "Transcription cofactor vestigial-like protein 3 gene" [UniProtKB:A8MV65] xref: EMBL:AC108709 xref: EMBL:BC094780 xref: EMBL:CH471110 xref: HGNC:HGNC:24327 xref: UniGene:Hs.435013 xref: UniGene:Hs.606507 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054056 ! VGLL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020448 name: VGLL4_human def: "Transcription cofactor vestigial-like protein 4 gene" [UniProtKB:Q14135] synonym: "KIAA0121" EXACT [UniProtKB:Q14135] xref: EMBL:AK130542 xref: EMBL:BC001514 xref: EMBL:BC003038 xref: EMBL:D50911 xref: HGNC:HGNC:28966 xref: UniGene:Hs.373959 xref: UniGene:Hs.38032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055960 ! VGLL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020449 name: SORBS3_human def: "Vinexin gene" [UniProtKB:O60504] synonym: "SCAM1" EXACT [UniProtKB:O60504] xref: EMBL:AF037261 xref: EMBL:AF064807 xref: EMBL:BC010146 xref: EMBL:BC091514 xref: HGNC:HGNC:30907 xref: UniGene:Hs.528572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054564 ! VINEX_HUMAN relationship: codes_for CCO:B0062920 ! Q96FY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020450 name: VIPR1_human def: "Vasoactive intestinal polypeptide receptor 1 precursor gene" [UniProtKB:P32241] xref: EMBL:AB065669 xref: EMBL:BC064424 xref: EMBL:L13288 xref: EMBL:L20295 xref: EMBL:U11079 xref: EMBL:U11080 xref: EMBL:U11081 xref: EMBL:U11083 xref: EMBL:U11084 xref: EMBL:U11085 xref: EMBL:U11086 xref: EMBL:U11087 xref: EMBL:X75299 xref: EMBL:X77777 xref: HGNC:HGNC:12694 xref: UniGene:Hs.348500 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055253 ! VIPR1_HUMAN relationship: codes_for CCO:B0056886 ! Q6P2M6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020451 name: VIPR2_human def: "Vasoactive intestinal polypeptide receptor 2 precursor gene" [UniProtKB:P41587] synonym: "VIP2R" EXACT [UniProtKB:P41587] xref: EMBL:BC010569 xref: EMBL:L36566 xref: EMBL:L40764 xref: EMBL:U18810 xref: EMBL:X95097 xref: EMBL:Y18423 xref: EMBL:Y18424 xref: EMBL:Y18425 xref: EMBL:Y18426 xref: EMBL:Y18427 xref: EMBL:Y18428 xref: EMBL:Y18429 xref: EMBL:Y18430 xref: EMBL:Y18431 xref: HGNC:HGNC:12695 xref: UniGene:Hs.654505 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055342 ! VIPR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020452 name: VIP_human def: "VIP peptides precursor gene" [UniProtKB:P01282] xref: EMBL:AL133356 xref: EMBL:BC009794 xref: EMBL:L00154 xref: EMBL:L00155 xref: EMBL:L00156 xref: EMBL:L00157 xref: EMBL:M11549 xref: EMBL:M11550 xref: EMBL:M11551 xref: EMBL:M11552 xref: EMBL:M11553 xref: EMBL:M14619 xref: EMBL:M14620 xref: EMBL:M14621 xref: EMBL:M14622 xref: EMBL:M14623 xref: EMBL:M31645 xref: EMBL:M32162 xref: EMBL:M33027 xref: EMBL:M36606 xref: EMBL:M36607 xref: EMBL:M36608 xref: EMBL:M36609 xref: EMBL:M36610 xref: EMBL:M36634 xref: EMBL:M54930 xref: HGNC:HGNC:12693 xref: UniGene:Hs.53973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054849 ! VIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020453 name: KNDC1_human def: "Protein very KIND gene" [UniProtKB:Q76NI1] synonym: "C10orf23" EXACT [UniProtKB:Q76NI1] synonym: "hucep-9" EXACT [UniProtKB:Q76NI1] synonym: "KIAA1768" EXACT [UniProtKB:Q76NI1] synonym: "RASGEF2" EXACT [UniProtKB:Q76NI1] synonym: "VKIND" EXACT [UniProtKB:Q76NI1] xref: EMBL:AB000781 xref: EMBL:AB051555 xref: EMBL:AK057756 xref: EMBL:AK074179 xref: EMBL:AK131205 xref: EMBL:AL445199 xref: HGNC:HGNC:29374 xref: UniGene:Hs.530685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057109 ! VKIND_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020454 name: VN1R1_human def: "Vomeronasal type-1 receptor 1 gene" [UniProtKB:Q9GZP7] synonym: "V1RL1" EXACT [UniProtKB:Q9GZP7] synonym: "VNR19I1" EXACT [UniProtKB:Q9GZP7] xref: EMBL:AB083606 xref: EMBL:AF255342 xref: EMBL:AF302903 xref: EMBL:AY312477 xref: EMBL:AY312478 xref: EMBL:AY312479 xref: EMBL:BC095508 xref: HGNC:HGNC:13548 xref: UniGene:Hs.388810 xref: UniGene:Hs.677423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058630 ! VN1R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020455 name: VN1R2_human def: "Vomeronasal type-1 receptor 2 gene" [UniProtKB:Q8NFZ6] synonym: "V1RL2" EXACT [UniProtKB:Q8NFZ6] xref: EMBL:AB083607 xref: EMBL:AF370359 xref: EMBL:AY312480 xref: EMBL:AY312481 xref: EMBL:AY312482 xref: HGNC:HGNC:19872 xref: UniGene:Hs.553684 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057610 ! VN1R2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020456 name: VN1R3_human def: "Vomeronasal type-1 receptor 3 gene" [UniProtKB:Q9BXE9] synonym: "FKSG46" EXACT [UniProtKB:Q9BXE9] synonym: "V1RL3" EXACT [UniProtKB:Q9BXE9] xref: EMBL:AF336873 xref: HGNC:HGNC:19867 xref: UniGene:Hs.257746 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058551 ! VN1R3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020457 name: VN1R4_human def: "Vomeronasal type-1 receptor 4 gene" [UniProtKB:Q7Z5H5] synonym: "V1RL4" EXACT [UniProtKB:Q7Z5H5] xref: EMBL:AB083609 xref: EMBL:AY114733 xref: EMBL:AY312485 xref: EMBL:AY312486 xref: EMBL:AY312487 xref: EMBL:AY312488 xref: EMBL:BC104935 xref: EMBL:BC104939 xref: HGNC:HGNC:19871 xref: UniGene:Hs.553685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057182 ! VN1R4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020458 name: VN1R5_human def: "Vomeronasal type-1 receptor 5 gene" [UniProtKB:Q7Z5H4] synonym: "V1RL5" EXACT [UniProtKB:Q7Z5H4] xref: EMBL:AB083608 xref: EMBL:AY114735 xref: EMBL:AY312489 xref: EMBL:AY312490 xref: EMBL:AY312491 xref: EMBL:BC126341 xref: EMBL:BC126367 xref: HGNC:HGNC:19870 xref: UniGene:Hs.553686 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057181 ! VN1R5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020459 name: VNN1_human def: "Pantetheinase precursor gene" [UniProtKB:O95497] xref: EMBL:AJ132099 xref: EMBL:AL032821 xref: EMBL:BC096265 xref: EMBL:BC096266 xref: EMBL:BC096267 xref: EMBL:BC096268 xref: EMBL:DQ100297 xref: EMBL:U39664 xref: HGNC:HGNC:12705 xref: UniGene:Hs.12114 xref: UniGene:Hs.700895 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054768 ! VNN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020460 name: VNRL4_human def: "Putative vomeronasal receptor-like protein 4 gene" [UniProtKB:Q8TDU5] xref: EMBL:AB083605 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057938 ! VNRL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020461 name: TCIRG1_human def: "V-type proton ATPase 116 kDa subunit a isoform 3 gene" [UniProtKB:Q13488] synonym: "ATP6N1C" EXACT [UniProtKB:Q13488] synonym: "ATP6V0A3" EXACT [UniProtKB:Q13488] xref: EMBL:AF025374 xref: EMBL:AF033033 xref: EMBL:U45285 xref: HGNC:HGNC:11647 xref: UniGene:Hs.495985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055916 ! VPP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020462 name: VPS25_human def: "Vacuolar protein-sorting-associated protein 25 gene" [UniProtKB:Q9BRG1] synonym: "DERP9" EXACT [UniProtKB:Q9BRG1] synonym: "EAP20" EXACT [UniProtKB:Q9BRG1] xref: EMBL:AB014763 xref: EMBL:BC006282 xref: HGNC:HGNC:28122 xref: UniGene:Hs.500165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058490 ! VPS25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020463 name: VPS36_human def: "Vacuolar protein-sorting-associated protein 36 gene" [UniProtKB:Q86VN1] synonym: "C13orf9" EXACT [UniProtKB:Q86VN1] synonym: "CGI-145" EXACT [UniProtKB:Q86VN1] synonym: "EAP45" EXACT [UniProtKB:Q86VN1] xref: EMBL:AF151903 xref: EMBL:AK023182 xref: EMBL:AL359513 xref: EMBL:BC037279 xref: EMBL:BC050439 xref: EMBL:CR933653 xref: HGNC:HGNC:20312 xref: UniGene:Hs.109520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057265 ! VPS36_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020464 name: VSIG4_human def: "V-set and immunoglobulin domain-containing protein 4 precursor gene" [UniProtKB:Q9Y279] synonym: "UNQ317/PRO362" EXACT [UniProtKB:Q9Y279] synonym: "Z39IG" EXACT [UniProtKB:Q9Y279] xref: EMBL:AJ132502 xref: EMBL:AY358341 xref: EMBL:BC010525 xref: HGNC:HGNC:17032 xref: UniGene:Hs.8904 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059297 ! VSIG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020465 name: VSX1_human def: "Visual system homeobox 1 gene" [UniProtKB:Q9NZR4] synonym: "RINX" EXACT [UniProtKB:Q9NZR4] xref: EMBL:AF176797 xref: EMBL:AF251033 xref: EMBL:AF251034 xref: EMBL:AL080312 xref: EMBL:BC126228 xref: EMBL:DQ854807 xref: EMBL:DQ854811 xref: HGNC:HGNC:12723 xref: UniGene:Hs.274264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055811 ! Q0GM61_HUMAN relationship: codes_for CCO:B0059013 ! VSX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020466 name: VSX2_human def: "Visual system homeobox 2 gene" [UniProtKB:P58304] synonym: "CHX10" EXACT [UniProtKB:P58304] synonym: "HOX10" EXACT [UniProtKB:P58304] xref: EMBL:AC005519 xref: EMBL:AC006349 xref: EMBL:AY336059 xref: HGNC:HGNC:1975 xref: UniGene:Hs.449771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055569 ! VSX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020467 name: VTI1B_human def: "Vesicle transport through interaction with t-SNAREs homolog 1B gene" [UniProtKB:Q9UEU0] synonym: "VTI1" EXACT [UniProtKB:Q9UEU0] synonym: "VTI1L" EXACT [UniProtKB:Q9UEU0] synonym: "VTI1L1" EXACT [UniProtKB:Q9UEU0] synonym: "VTI2" EXACT [UniProtKB:Q9UEU0] xref: EMBL:AF035824 xref: EMBL:AF060902 xref: EMBL:BC003142 xref: EMBL:BT019348 xref: EMBL:CR456757 xref: EMBL:CR542095 xref: HGNC:HGNC:17793 xref: UniGene:Hs.645419 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059110 ! VTI1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020468 name: VWC2_human def: "Brorin precursor gene" [UniProtKB:Q2TAL6] synonym: "UNQ739/PRO1434" EXACT [UniProtKB:Q2TAL6] xref: EMBL:AB292671 xref: EMBL:AY358393 xref: EMBL:BC110857 xref: EMBL:CH236955 xref: EMBL:CH471128 xref: HGNC:HGNC:30200 xref: UniGene:Hs.677488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056226 ! VWC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020469 name: WASF2_human def: "Wiskott-Aldrich syndrome protein family member 2 gene" [UniProtKB:Q9Y6W5] synonym: "WAVE2" EXACT [UniProtKB:Q9Y6W5] xref: EMBL:AB026542 xref: EMBL:AL096774 xref: EMBL:BC040943 xref: HGNC:HGNC:12733 xref: UniGene:Hs.590909 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059418 ! WASF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020470 name: WASF4_human def: "Wiskott-Aldrich syndrome protein family member 4 gene" [UniProtKB:Q8IV90] synonym: "SCAR2" EXACT [UniProtKB:Q8IV90] xref: EMBL:AF134304 xref: EMBL:AJ509090 xref: HGNC:HGNC:20801 xref: UniGene:Hs.512079 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057340 ! WASF4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020471 name: MLXIPL_human def: "Williams-Beuren syndrome chromosomal region 14 protein gene" [UniProtKB:Q9NP71] synonym: "MIO" EXACT [UniProtKB:Q9NP71] synonym: "WBSCR14" EXACT [UniProtKB:Q9NP71] xref: EMBL:AF056184 xref: EMBL:AF156603 xref: EMBL:AF156673 xref: EMBL:AF245470 xref: EMBL:AF245471 xref: EMBL:AF245472 xref: EMBL:AF245473 xref: EMBL:AF245474 xref: EMBL:BC012925 xref: HGNC:HGNC:12744 xref: UniGene:Hs.647055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058835 ! WBS14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020472 name: WDR12_human def: "WD repeat-containing protein 12 gene" [UniProtKB:Q9GZL7] xref: EMBL:AF242546 xref: EMBL:AK001743 xref: EMBL:AK022781 xref: EMBL:AK022782 xref: EMBL:BC008082 xref: HGNC:HGNC:14098 xref: UniGene:Hs.73291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058628 ! WDR12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020473 name: WDR67_human def: "WD repeat-containing protein 67 gene" [UniProtKB:Q96DN5] xref: EMBL:AK056434 xref: EMBL:BC027237 xref: EMBL:BC101724 xref: EMBL:BC111954 xref: HGNC:HGNC:30888 xref: UniGene:Hs.492716 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058194 ! WDR67_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020474 name: WFDC1_human def: "WAP four-disulfide core domain protein 1 precursor gene" [UniProtKB:Q9HC57] synonym: "PS20" EXACT [UniProtKB:Q9HC57] xref: EMBL:AF169631 xref: EMBL:AF302109 xref: EMBL:AK075061 xref: EMBL:BC029159 xref: HGNC:HGNC:15466 xref: UniGene:Hs.36688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058798 ! WFDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020475 name: WFS1_human def: "Wolframin gene" [UniProtKB:O76024] xref: EMBL:AF084481 xref: EMBL:BC030130 xref: EMBL:Y18064 xref: HGNC:HGNC:12762 xref: UniGene:Hs.518602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054687 ! WFS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020476 name: WIF1_human def: "Wnt inhibitory factor 1 precursor gene" [UniProtKB:Q9Y5W5] synonym: "UNQ191/PRO217" EXACT [UniProtKB:Q9Y5W5] xref: EMBL:AF122922 xref: EMBL:AY358344 xref: EMBL:BC018037 xref: HGNC:HGNC:18081 xref: UniGene:Hs.284122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059389 ! WIF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020477 name: WISP3_human def: "WNT1-inducible-signaling pathway protein 3 precursor gene" [UniProtKB:O95389] synonym: "CCN6" EXACT [UniProtKB:O95389] synonym: "UNQ462/PRO790/PRO956" EXACT [UniProtKB:O95389] xref: EMBL:AF100781 xref: EMBL:AL512299 xref: EMBL:AY358349 xref: EMBL:AY358350 xref: EMBL:BC105940 xref: EMBL:BC105941 xref: EMBL:CH471051 xref: EMBL:Z99289 xref: HGNC:HGNC:12771 xref: UniGene:Hs.558428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054755 ! WISP3_HUMAN relationship: codes_for CCO:B0056257 ! Q3KR29_HUMAN relationship: codes_for CCO:B0056258 ! Q3KR30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020478 name: WNT10A_human def: "Protein Wnt-10a precursor gene" [UniProtKB:Q9GZT5] xref: EMBL:AB059569 xref: EMBL:AF315943 xref: EMBL:AK024363 xref: EMBL:AY009400 xref: EMBL:BC052234 xref: HGNC:HGNC:13829 xref: UniGene:Hs.121540 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058636 ! WN10A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020479 name: WNT10B_human def: "Protein Wnt-10b precursor gene" [UniProtKB:O00744] synonym: "WNT12" EXACT [UniProtKB:O00744] xref: EMBL:AB070724 xref: EMBL:AC073610 xref: EMBL:AF028700 xref: EMBL:BC096353 xref: EMBL:BC096354 xref: EMBL:BC096355 xref: EMBL:BC096356 xref: EMBL:U81787 xref: EMBL:X97057 xref: HGNC:HGNC:12775 xref: UniGene:Hs.91985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053803 ! A6NE61_HUMAN relationship: codes_for CCO:B0054340 ! WN10B_HUMAN relationship: codes_for CCO:B0056327 ! Q4VAJ4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020480 name: WNK1_human def: "Serine/threonine-protein kinase WNK1 gene" [UniProtKB:Q9H4A3] synonym: "KDP" EXACT [UniProtKB:Q9H4A3] synonym: "KIAA0344" EXACT [UniProtKB:Q9H4A3] synonym: "PRKWNK1" EXACT [UniProtKB:Q9H4A3] xref: EMBL:AB002342 xref: EMBL:AF061944 xref: EMBL:AJ296290 xref: EMBL:AY231477 xref: EMBL:BC021121 xref: HGNC:HGNC:14540 xref: UniGene:Hs.356604 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058713 ! WNK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020481 name: WNK2_human def: "Serine/threonine-protein kinase WNK2 gene" [UniProtKB:Q9Y3S1] synonym: "KIAA1760" EXACT [UniProtKB:Q9Y3S1] synonym: "P/OKcl.13" EXACT [UniProtKB:Q9Y3S1] synonym: "PRKWNK2" EXACT [UniProtKB:Q9Y3S1] synonym: "SDCCAG43" EXACT [UniProtKB:Q9Y3S1] xref: EMBL:AB044546 xref: EMBL:AB051547 xref: EMBL:AJ242724 xref: EMBL:BC037965 xref: HGNC:HGNC:14542 xref: UniGene:Hs.654856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059344 ! WNK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020482 name: WNK3_human def: "Serine/threonine-protein kinase WNK3 gene" [UniProtKB:Q9BYP7] synonym: "KIAA1566" EXACT [UniProtKB:Q9BYP7] synonym: "PRKWNK3" EXACT [UniProtKB:Q9BYP7] xref: EMBL:AB046786 xref: EMBL:AJ409088 xref: EMBL:AL049793 xref: EMBL:AL591766 xref: EMBL:AY082340 xref: EMBL:AY352048 xref: EMBL:Z84469 xref: HGNC:HGNC:14543 xref: UniGene:Hs.92423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058581 ! WNK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020483 name: WNT11_human def: "Protein Wnt-11 precursor gene" [UniProtKB:O96014] xref: EMBL:AB070218 xref: EMBL:BC074790 xref: EMBL:BC074791 xref: EMBL:BC113386 xref: EMBL:BC113388 xref: EMBL:Y12692 xref: EMBL:Y13843 xref: EMBL:Y13844 xref: EMBL:Y13845 xref: EMBL:Y13846 xref: EMBL:Y13847 xref: HGNC:HGNC:12776 xref: UniGene:Hs.108219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054822 ! WNT11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020484 name: WNT1_human def: "Proto-oncogene protein Wnt-1 precursor gene" [UniProtKB:P04628] synonym: "INT1" EXACT [UniProtKB:P04628] xref: EMBL:AC073610 xref: EMBL:BC074798 xref: EMBL:BC074799 xref: EMBL:X03072 xref: HGNC:HGNC:12774 xref: UniGene:Hs.248164 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053810 ! A6NEV2_HUMAN relationship: codes_for CCO:B0054891 ! WNT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020485 name: WNT2B_human def: "Protein Wnt-2b precursor gene" [UniProtKB:Q93097] synonym: "WNT13" EXACT [UniProtKB:Q93097] xref: EMBL:AB045116 xref: EMBL:AB045117 xref: EMBL:AF028701 xref: EMBL:AL109932 xref: EMBL:AL354760 xref: EMBL:Z71621 xref: HGNC:HGNC:12781 xref: UniGene:Hs.258575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056613 ! Q5TEH8_HUMAN relationship: codes_for CCO:B0058124 ! WNT2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020486 name: WNT2_human def: "Protein Wnt-2 precursor gene" [UniProtKB:P09544] synonym: "INT1L1" EXACT [UniProtKB:P09544] synonym: "IRP" EXACT [UniProtKB:P09544] xref: EMBL:AC002465 xref: EMBL:AC006326 xref: EMBL:BC029854 xref: EMBL:BC078170 xref: EMBL:BT019608 xref: EMBL:X07876 xref: HGNC:HGNC:12780 xref: UniGene:Hs.567356 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054945 ! WNT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020487 name: WNT3A_human def: "Protein Wnt-3a precursor gene" [UniProtKB:P56704] xref: EMBL:AB060284 xref: EMBL:AK056278 xref: EMBL:AL136379 xref: EMBL:BC103921 xref: EMBL:BC103922 xref: EMBL:BC103923 xref: HGNC:HGNC:15983 xref: UniGene:Hs.336930 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055549 ! WNT3A_HUMAN relationship: codes_for CCO:B0056271 ! Q3SY79_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020488 name: WNT3_human def: "Proto-oncogene protein Wnt-3 precursor gene" [UniProtKB:P56703] synonym: "INT4" EXACT [UniProtKB:P56703] xref: EMBL:AB067628 xref: EMBL:AY009397 xref: EMBL:BC112116 xref: EMBL:BC112118 xref: EMBL:BC114219 xref: HGNC:HGNC:12782 xref: UniGene:Hs.445884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055548 ! WNT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020489 name: WNT4_human def: "Protein Wnt-4 precursor gene" [UniProtKB:P56705] synonym: "UNQ426/PRO864" EXACT [UniProtKB:P56705] xref: EMBL:AF316543 xref: EMBL:AF335591 xref: EMBL:AL031281 xref: EMBL:AL445253 xref: EMBL:AY009398 xref: EMBL:AY033057 xref: EMBL:AY358947 xref: EMBL:BC057781 xref: EMBL:BT020125 xref: HGNC:HGNC:12783 xref: UniGene:Hs.25766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054223 ! B1AJZ6_HUMAN relationship: codes_for CCO:B0055550 ! WNT4_HUMAN relationship: codes_for CCO:B0056513 ! Q5JYX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020490 name: WNT5A_human def: "Protein Wnt-5a precursor gene" [UniProtKB:P41221] xref: EMBL:AK290375 xref: EMBL:AK290869 xref: EMBL:BC064694 xref: EMBL:CH471055 xref: EMBL:L20861 xref: HGNC:HGNC:12784 xref: UniGene:Hs.696364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055336 ! WNT5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020491 name: WNT5B_human def: "Protein Wnt-5b precursor gene" [UniProtKB:Q9H1J7] xref: EMBL:AB060966 xref: EMBL:AY009399 xref: EMBL:BC001749 xref: HGNC:HGNC:16265 xref: UniGene:Hs.306051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058666 ! WNT5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020492 name: WNT6_human def: "Protein Wnt-6 precursor gene" [UniProtKB:Q9Y6F9] xref: EMBL:AB059570 xref: EMBL:AF079522 xref: EMBL:AF315943 xref: EMBL:AY009401 xref: EMBL:BC004329 xref: EMBL:BT007456 xref: HGNC:HGNC:12785 xref: UniGene:Hs.29764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059405 ! WNT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020493 name: WNT7A_human def: "Protein Wnt-7a precursor gene" [UniProtKB:O00755] xref: EMBL:D83175 xref: EMBL:U53476 xref: HGNC:HGNC:12786 xref: UniGene:Hs.72290 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054341 ! WNT7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020494 name: WNT7B_human def: "Protein Wnt-7b precursor gene" [UniProtKB:P56706] xref: EMBL:AB062766 xref: EMBL:AF416743 xref: EMBL:BC034923 xref: HGNC:HGNC:12787 xref: UniGene:Hs.512714 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055551 ! WNT7B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020495 name: WNT8A_human def: "Protein Wnt-8a precursor gene" [UniProtKB:Q9H1J5] synonym: "WNT8D" EXACT [UniProtKB:Q9H1J5] xref: EMBL:AB057725 xref: EMBL:AY009402 xref: HGNC:HGNC:12788 xref: UniGene:Hs.591274 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058665 ! WNT8A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020496 name: WNT8B_human def: "Protein Wnt-8b precursor gene" [UniProtKB:Q93098] xref: EMBL:AB073637 xref: EMBL:AL133352 xref: EMBL:AL359759 xref: EMBL:X91940 xref: EMBL:Y11094 xref: EMBL:Y11108 xref: HGNC:HGNC:12789 xref: UniGene:Hs.421281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058125 ! WNT8B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020497 name: WNT9A_human def: "Protein Wnt-9a precursor gene" [UniProtKB:O14904] synonym: "WNT14" EXACT [UniProtKB:O14904] xref: EMBL:AB060283 xref: EMBL:AF028702 xref: EMBL:AL360269 xref: EMBL:BC111960 xref: EMBL:BC113431 xref: EMBL:CH471098 xref: HGNC:HGNC:12778 xref: UniGene:Hs.149504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054388 ! WNT9A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020498 name: WNT9B_human def: "Protein Wnt-9b precursor gene" [UniProtKB:O14905] synonym: "UNQ6973/PRO21956" EXACT [UniProtKB:O14905] synonym: "WNT14B" EXACT [UniProtKB:O14905] synonym: "WNT15" EXACT [UniProtKB:O14905] xref: EMBL:AB063483 xref: EMBL:AF028703 xref: EMBL:AK127615 xref: EMBL:AY358217 xref: EMBL:BC064534 xref: HGNC:HGNC:12779 xref: UniGene:Hs.326420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054389 ! WNT9B_HUMAN relationship: codes_for CCO:B0057051 ! Q6ZS96_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020499 name: WRNIP1_human def: "ATPase WRNIP1 gene" [UniProtKB:Q96S55] synonym: "WHIP" EXACT [UniProtKB:Q96S55] xref: EMBL:AB056152 xref: EMBL:AB209723 xref: EMBL:AF218313 xref: EMBL:AK026179 xref: EMBL:AK223593 xref: EMBL:AL139092 xref: EMBL:BC018923 xref: HGNC:HGNC:20876 xref: UniGene:Hs.236828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058386 ! WRIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020500 name: WSB1_human def: "WD repeat and SOCS box-containing protein 1 gene" [UniProtKB:Q9Y6I7] synonym: "SWIP1" EXACT [UniProtKB:Q9Y6I7] xref: EMBL:AF069313 xref: EMBL:AF072880 xref: EMBL:AF106683 xref: EMBL:AF112205 xref: EMBL:AF240696 xref: EMBL:AL110243 xref: EMBL:BC005226 xref: EMBL:BC021110 xref: HGNC:HGNC:19221 xref: UniGene:Hs.446017 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053700 ! A0JLP1_HUMAN relationship: codes_for CCO:B0059406 ! WSB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020501 name: WSB2_human def: "WD repeat and SOCS box-containing protein 2 gene" [UniProtKB:Q9NYS7] xref: EMBL:AF163324 xref: EMBL:AF229181 xref: EMBL:BC015887 xref: HGNC:HGNC:19222 xref: UniGene:Hs.506985 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058971 ! WSB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020502 name: WWP1_human def: "NEDD4-like E3 ubiquitin-protein ligase WWP1 gene" [UniProtKB:Q9H0M0] xref: EMBL:AL136739 xref: EMBL:AY043361 xref: EMBL:BC015380 xref: EMBL:BC036065 xref: EMBL:U96113 xref: HGNC:HGNC:17004 xref: UniGene:Hs.655189 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058653 ! WWP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020503 name: WWTR1_human def: "WW domain-containing transcription regulator protein 1 gene" [UniProtKB:Q9GZV5] synonym: "TAZ" EXACT [UniProtKB:Q9GZV5] xref: EMBL:AJ299431 xref: EMBL:AK022036 xref: EMBL:AL050107 xref: EMBL:AL833852 xref: EMBL:BC014052 xref: HGNC:HGNC:24042 xref: UniGene:Hs.699296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058638 ! WWTR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020504 name: CX3CL1_human def: "Fractalkine precursor gene" [UniProtKB:P78423] synonym: "A-152E5.2" EXACT [UniProtKB:P78423] synonym: "FKN" EXACT [UniProtKB:P78423] synonym: "NTT" EXACT [UniProtKB:P78423] synonym: "SCYD1" EXACT [UniProtKB:P78423] xref: EMBL:AC004382 xref: EMBL:BC001163 xref: EMBL:BC016164 xref: EMBL:U84487 xref: EMBL:U91835 xref: HGNC:HGNC:10647 xref: UniGene:Hs.531668 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055645 ! X3CL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020505 name: XBP1_human def: "X-box-binding protein 1 gene" [UniProtKB:P17861] synonym: "TREB5" EXACT [UniProtKB:P17861] synonym: "XBP2" EXACT [UniProtKB:P17861] xref: EMBL:AB076383 xref: EMBL:AB076384 xref: EMBL:BC000938 xref: EMBL:BC012841 xref: EMBL:BC015709 xref: EMBL:CR456611 xref: EMBL:L13850 xref: EMBL:M31627 xref: EMBL:X55543 xref: EMBL:Z93930 xref: HGNC:HGNC:12801 xref: UniGene:Hs.437638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054212 ! B1AHH1_HUMAN relationship: codes_for CCO:B0054213 ! B1AHH2_HUMAN relationship: codes_for CCO:B0055093 ! XBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020506 name: XCL1_human def: "Lymphotactin precursor gene" [UniProtKB:P47992] synonym: "LTN" EXACT [UniProtKB:P47992] synonym: "SCYC1" EXACT [UniProtKB:P47992] xref: EMBL:AL031736 xref: EMBL:BC069817 xref: EMBL:BC070309 xref: EMBL:D43768 xref: EMBL:D63790 xref: EMBL:U23772 xref: EMBL:X86474 xref: HGNC:HGNC:10645 xref: UniGene:Hs.546295 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055397 ! XCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020507 name: XCL2_human def: "Cytokine SCM-1 beta precursor gene" [UniProtKB:Q9UBD3] synonym: "SCYC2" EXACT [UniProtKB:Q9UBD3] xref: EMBL:AL031736 xref: EMBL:BC069360 xref: EMBL:BC070308 xref: EMBL:D63789 xref: HGNC:HGNC:10646 xref: UniGene:Hs.458346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059068 ! XCL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020508 name: XCR1_human def: "Chemokine XC receptor 1 gene" [UniProtKB:P46094] synonym: "CCXCR1" EXACT [UniProtKB:P46094] synonym: "GPR5" EXACT [UniProtKB:P46094] xref: EMBL:AY275469 xref: EMBL:BC069075 xref: EMBL:BC069589 xref: EMBL:L36149 xref: HGNC:HGNC:1625 xref: UniGene:Hs.248116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055374 ! XCR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020509 name: XDH_human def: "Xanthine dehydrogenase/oxidase gene" [UniProtKB:P47989] synonym: "XDHA" EXACT [UniProtKB:P47989] xref: EMBL:D11456 xref: EMBL:DQ089481 xref: EMBL:U06117 xref: EMBL:U39487 xref: HGNC:HGNC:12805 xref: UniGene:Hs.250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055396 ! XDH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020510 name: XPR1_human def: "Xenotropic and polytropic retrovirus receptor 1 gene" [UniProtKB:Q9UBH6] synonym: "SYG1" EXACT [UniProtKB:Q9UBH6] synonym: "XR" EXACT [UniProtKB:Q9UBH6] xref: EMBL:AF089744 xref: EMBL:AF099082 xref: EMBL:AF115389 xref: EMBL:AL133058 xref: EMBL:AL137583 xref: EMBL:AL162431 xref: EMBL:AL358434 xref: EMBL:AL590085 xref: EMBL:BC041142 xref: EMBL:CH471067 xref: HGNC:HGNC:12827 xref: UniGene:Hs.227656 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059074 ! XPR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020511 name: YAF2_human def: "YY1-associated factor 2 gene" [UniProtKB:Q8IY57] xref: EMBL:AC020629 xref: EMBL:BC037777 xref: EMBL:U72209 xref: HGNC:HGNC:17363 xref: UniGene:Hs.699313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057384 ! YAF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020512 name: YAP1_human def: "65 kDa Yes-associated protein gene" [UniProtKB:P46937] synonym: "YAP65" EXACT [UniProtKB:P46937] xref: EMBL:X80507 xref: HGNC:HGNC:16262 xref: UniGene:Hs.503692 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055381 ! YAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020513 name: YEATS2_human def: "YEATS domain-containing protein 2 gene" [UniProtKB:Q9ULM3] synonym: "KIAA1197" EXACT [UniProtKB:Q9ULM3] xref: EMBL:AB033023 xref: EMBL:AK001063 xref: EMBL:BC032368 xref: EMBL:BC082270 xref: HGNC:HGNC:25489 xref: UniGene:Hs.632575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057473 ! Q8N5H6_HUMAN relationship: codes_for CCO:B0059230 ! YETS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020514 name: ZNF280A_human def: "Zinc finger protein 280A gene" [UniProtKB:P59817] synonym: "SUHW1" EXACT [UniProtKB:P59817] synonym: "ZNF280" EXACT [UniProtKB:P59817] xref: EMBL:BC053901 xref: EMBL:D87009 xref: EMBL:D87011 xref: HGNC:HGNC:18597 xref: UniGene:Hs.178665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055590 ! Z280A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020515 name: ZNF280B_human def: "Zinc finger protein 280B gene" [UniProtKB:Q86YH2] synonym: "SUHW2" EXACT [UniProtKB:Q86YH2] synonym: "ZNF279" EXACT [UniProtKB:Q86YH2] synonym: "ZNF632" EXACT [UniProtKB:Q86YH2] xref: EMBL:BC040020 xref: EMBL:CR456614 xref: EMBL:D87009 xref: HGNC:HGNC:23022 xref: UniGene:Hs.43834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057304 ! Z280B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020516 name: ZNF280C_human def: "Zinc finger protein 280C gene" [UniProtKB:Q8ND82] synonym: "SUHW3" EXACT [UniProtKB:Q8ND82] xref: EMBL:AK000102 xref: EMBL:AL023799 xref: EMBL:AL139234 xref: EMBL:AL834333 xref: EMBL:BC051728 xref: HGNC:HGNC:25955 xref: UniGene:Hs.308418 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057575 ! Z280C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020517 name: ZNF280D_human def: "Zinc finger protein 280D gene" [UniProtKB:Q6N043] synonym: "KIAA1584" EXACT [UniProtKB:Q6N043] synonym: "SUHW4" EXACT [UniProtKB:Q6N043] xref: EMBL:AB046804 xref: EMBL:AK000093 xref: EMBL:AL136634 xref: EMBL:BX640637 xref: EMBL:BX640707 xref: EMBL:BX641000 xref: HGNC:HGNC:25953 xref: UniGene:Hs.511477 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056846 ! Z280D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020518 name: ZNF286A_human def: "Zinc finger protein 286A gene" [UniProtKB:Q9HBT8] synonym: "KIAA1874" EXACT [UniProtKB:Q9HBT8] synonym: "ZNF286" EXACT [UniProtKB:Q9HBT8] xref: EMBL:AB058777 xref: EMBL:AC005324 xref: EMBL:AF217226 xref: HGNC:HGNC:13501 xref: UniGene:Hs.585799 xref: UniGene:Hs.659318 xref: UniGene:Hs.660199 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054034 ! A8MTT8_HUMAN relationship: codes_for CCO:B0058791 ! Z286A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020519 name: ZNF322A_human def: "Zinc finger protein 322A gene" [UniProtKB:Q6U7Q0] synonym: "ZNF322" EXACT [UniProtKB:Q6U7Q0] synonym: "ZNF388" EXACT [UniProtKB:Q6U7Q0] synonym: "ZNF489" EXACT [UniProtKB:Q6U7Q0] xref: EMBL:AK027046 xref: EMBL:AY376736 xref: EMBL:BC050425 xref: EMBL:BC074772 xref: EMBL:BC119669 xref: HGNC:HGNC:23640 xref: UniGene:Hs.126280 xref: UniGene:Hs.530271 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056947 ! Z322A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020520 name: ZNF322B_human def: "Zinc finger protein 322B gene" [UniProtKB:Q5SYY0] xref: EMBL:AL590705 xref: HGNC:HGNC:14003 xref: UniGene:Hs.530271 xref: UniGene:Hs.648180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056553 ! Z322B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020521 name: ZNF324_human def: "Zinc finger protein 324A gene" [UniProtKB:O75467] synonym: "ZNF324A" EXACT [UniProtKB:O75467] xref: EMBL:AF060503 xref: HGNC:HGNC:14096 xref: UniGene:Hs.515660 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054638 ! Z324A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020522 name: ZNF324B_human def: "Zinc finger protein 324B gene" [UniProtKB:Q6AW86] xref: EMBL:AK127750 xref: EMBL:AK131452 xref: EMBL:BX648711 xref: HGNC:HGNC:33107 xref: UniGene:Hs.186970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056718 ! Z324B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020523 name: ZNF354A_human def: "Zinc finger protein 354A gene" [UniProtKB:O60765] synonym: "EZNF" EXACT [UniProtKB:O60765] synonym: "HKL1" EXACT [UniProtKB:O60765] synonym: "TCF17" EXACT [UniProtKB:O60765] xref: EMBL:AF116030 xref: EMBL:D89928 xref: HGNC:HGNC:11628 xref: UniGene:Hs.484324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054579 ! Z354A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020524 name: ZNF354B_human def: "Zinc finger protein 354B gene" [UniProtKB:Q96LW1] xref: EMBL:AK057737 xref: EMBL:BC104777 xref: EMBL:BC112111 xref: HGNC:HGNC:17197 xref: UniGene:Hs.591734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058274 ! Z354B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020525 name: ZNF354C_human def: "Zinc finger protein 354C gene" [UniProtKB:Q86Y25] synonym: "KID3" EXACT [UniProtKB:Q86Y25] xref: EMBL:AF395540 xref: EMBL:AF525463 xref: EMBL:BC063312 xref: HGNC:HGNC:16736 xref: UniGene:Hs.445740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057299 ! Z354C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020526 name: ZNF385A_human def: "Zinc finger protein 385A gene" [UniProtKB:Q96PM9] synonym: "HZF" EXACT [UniProtKB:Q96PM9] synonym: "RZF" EXACT [UniProtKB:Q96PM9] synonym: "ZNF385" EXACT [UniProtKB:Q96PM9] xref: EMBL:AF304052 xref: EMBL:AK024404 xref: EMBL:AL117462 xref: EMBL:AY461717 xref: EMBL:BC029752 xref: EMBL:CR457327 xref: HGNC:HGNC:17521 xref: UniGene:Hs.505653 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058338 ! Z385A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020527 name: ZNF397OS_human def: "Zinc finger protein 397OS gene" [UniProtKB:Q86W11] xref: EMBL:AC011815 xref: EMBL:AF303374 xref: EMBL:AK131291 xref: EMBL:AY234408 xref: HGNC:HGNC:33517 xref: UniGene:Hs.464896 xref: UniGene:Hs.591061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053820 ! A6NFE1_HUMAN relationship: codes_for CCO:B0057271 ! Z397O_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020528 name: ZNF512B_human def: "Zinc finger protein 512B gene" [UniProtKB:Q96KM6] synonym: "KIAA1196" EXACT [UniProtKB:Q96KM6] xref: EMBL:AB033022 xref: EMBL:AL118506 xref: EMBL:AL834525 xref: EMBL:BC125128 xref: EMBL:BC125129 xref: HGNC:HGNC:29212 xref: UniGene:Hs.551552 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058260 ! Z512B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020529 name: ZNF518A_human def: "Zinc finger protein 518A gene" [UniProtKB:Q6AHZ1] synonym: "KIAA0335" EXACT [UniProtKB:Q6AHZ1] synonym: "ZNF518" EXACT [UniProtKB:Q6AHZ1] xref: EMBL:AB002333 xref: EMBL:BC030967 xref: EMBL:BC109045 xref: EMBL:BC109046 xref: EMBL:CR627437 xref: HGNC:HGNC:29009 xref: UniGene:Hs.657337 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056715 ! Z518A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020530 name: ZNF518B_human def: "Zinc finger protein 518B gene" [UniProtKB:Q9C0D4] synonym: "KIAA1729" EXACT [UniProtKB:Q9C0D4] xref: EMBL:AB051516 xref: EMBL:AC110768 xref: EMBL:AK058072 xref: HGNC:HGNC:29365 xref: UniGene:Hs.455089 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058616 ! Z518B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020531 name: ZNF585A_human def: "Zinc finger protein 585A gene" [UniProtKB:Q6P3V2] xref: EMBL:AK056389 xref: EMBL:AK074345 xref: EMBL:BC026081 xref: EMBL:BC063820 xref: HGNC:HGNC:26305 xref: UniGene:Hs.390568 xref: UniGene:Hs.659236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056888 ! Z585A_HUMAN relationship: codes_for CCO:B0057912 ! Q8TC43_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020532 name: ZNF585B_human def: "Zinc finger protein 585B gene" [UniProtKB:Q52M93] xref: EMBL:AK027834 xref: EMBL:AY147015 xref: EMBL:BC093625 xref: HGNC:HGNC:30948 xref: UniGene:Hs.631552 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056344 ! Z585B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020533 name: ZNF658B_human def: "Zinc finger protein 658B gene" [UniProtKB:Q4V348] xref: EMBL:AK095694 xref: EMBL:AL590491 xref: EMBL:BX248098 xref: HGNC:HGNC:32033 xref: UniGene:Hs.534812 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054017 ! A8MSY8_HUMAN relationship: codes_for CCO:B0056325 ! Z658B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020534 name: ZNF705A_human def: "Zinc finger protein 705A gene" [UniProtKB:Q6ZN79] xref: EMBL:AK131339 xref: HGNC:HGNC:32281 xref: UniGene:Hs.438536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057015 ! Z705A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020535 name: ZNF705C_human def: "Zinc finger protein 705C gene" [UniProtKB:Q2TAN0] synonym: "ZNF705CP" EXACT [UniProtKB:Q2TAN0] xref: EMBL:BC110823 xref: HGNC:HGNC:32283 xref: UniGene:Hs.652228 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056228 ! Z705C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020536 name: ZNF705D_human def: "Zinc finger protein 705D gene" [UniProtKB:A8K971] xref: EMBL:AC130365 xref: EMBL:AK292586 xref: HGNC:HGNC:33202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053981 ! Z705D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020537 name: ZNF705F_human def: "Zinc finger protein 705F gene" [UniProtKB:A8MVS1] xref: EMBL:AC087203 xref: HGNC:HGNC:33204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054065 ! Z705F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020538 name: ZNF780A_human def: "Zinc finger protein 780A gene" [UniProtKB:O75290] xref: EMBL:AC005614 xref: EMBL:BC021982 xref: HGNC:HGNC:27603 xref: UniGene:Hs.661726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054614 ! Z780A_HUMAN relationship: codes_for CCO:B0055757 ! Q05CQ7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020539 name: ZNF780B_human def: "Zinc finger protein 780B gene" [UniProtKB:Q9Y6R6] synonym: "ZNF779" EXACT [UniProtKB:Q9Y6R6] xref: EMBL:AC007842 xref: HGNC:HGNC:33109 xref: UniGene:Hs.599728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059415 ! Z780B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020540 name: ZNF816A_human def: "Zinc finger protein 816A gene" [UniProtKB:Q0VGE8] xref: EMBL:AL713804 xref: EMBL:BC105739 xref: EMBL:BC105740 xref: EMBL:BC105930 xref: HGNC:HGNC:26995 xref: UniGene:Hs.655592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017097 ! Z816A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020541 name: AZGP1_human def: "Zinc-alpha-2-glycoprotein precursor gene" [UniProtKB:P25311] synonym: "ZAG" EXACT [UniProtKB:P25311] synonym: "ZNGP1" EXACT [UniProtKB:P25311] xref: EMBL:AC004522 xref: EMBL:BC005306 xref: EMBL:BC033830 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: EMBL:D14034 xref: EMBL:D90427 xref: EMBL:M76707 xref: EMBL:X59766 xref: EMBL:X69953 xref: HGNC:HGNC:910 xref: UniGene:Hs.546239 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055183 ! ZA2G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020542 name: ZAP70_human def: "Tyrosine-protein kinase ZAP-70 gene" [UniProtKB:P43403] synonym: "SRK" EXACT [UniProtKB:P43403] xref: EMBL:AB083211 xref: EMBL:AC016699 xref: EMBL:BC039039 xref: EMBL:BC053878 xref: EMBL:L05148 xref: HGNC:HGNC:12858 xref: UniGene:Hs.234569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055364 ! ZAP70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020543 name: ZBTB10_human def: "Zinc finger and BTB domain-containing protein 10 gene" [UniProtKB:Q96DT7] synonym: "RINZF" EXACT [UniProtKB:Q96DT7] synonym: "RINZFC" EXACT [UniProtKB:Q96DT7] xref: EMBL:AJ319673 xref: EMBL:AJ507398 xref: EMBL:AK056913 xref: EMBL:BC050061 xref: HGNC:HGNC:30953 xref: UniGene:Hs.591868 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058198 ! ZBT10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020544 name: ZBTB11_human def: "Zinc finger and BTB domain-containing protein 11 gene" [UniProtKB:O95625] xref: EMBL:AK312859 xref: EMBL:BC111700 xref: EMBL:CH471052 xref: EMBL:U69274 xref: HGNC:HGNC:16740 xref: UniGene:Hs.655286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054774 ! ZBT11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020545 name: ZBTB12_human def: "Zinc finger and BTB domain-containing protein 12 gene" [UniProtKB:Q9Y330] synonym: "C6orf46" EXACT [UniProtKB:Q9Y330] synonym: "G10" EXACT [UniProtKB:Q9Y330] synonym: "NG35" EXACT [UniProtKB:Q9Y330] xref: EMBL:AF134726 xref: EMBL:AL662834 xref: EMBL:AL671762 xref: EMBL:AL844853 xref: EMBL:BA000025 xref: EMBL:BC043609 xref: HGNC:HGNC:19066 xref: UniGene:Hs.234027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059329 ! ZBT12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020546 name: ZBTB16_human def: "Zinc finger and BTB domain-containing protein 16 gene" [UniProtKB:Q05516] synonym: "PLZF" EXACT [UniProtKB:Q05516] synonym: "ZNF145" EXACT [UniProtKB:Q05516] xref: EMBL:AF060568 xref: EMBL:BC026902 xref: EMBL:BC029812 xref: EMBL:S60093 xref: EMBL:Z19002 xref: HGNC:HGNC:12930 xref: UniGene:Hs.591945 xref: UniGene:Hs.682144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055743 ! ZBT16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020547 name: ZBTB20_human def: "Zinc finger and BTB domain-containing protein 20 gene" [UniProtKB:Q9HC78] synonym: "DPZF" EXACT [UniProtKB:Q9HC78] synonym: "ZNF288" EXACT [UniProtKB:Q9HC78] xref: EMBL:AF139460 xref: EMBL:AL050276 xref: EMBL:BC029041 xref: EMBL:BX647778 xref: EMBL:CH471052 xref: HGNC:HGNC:13503 xref: UniGene:Hs.655108 xref: UniGene:Hs.693802 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058799 ! ZBT20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020548 name: ZBTB22_human def: "Zinc finger and BTB domain-containing protein 22 gene" [UniProtKB:O15209] synonym: "BING1" EXACT [UniProtKB:O15209] synonym: "ZBTB22A" EXACT [UniProtKB:O15209] synonym: "ZNF297" EXACT [UniProtKB:O15209] xref: EMBL:AK315747 xref: EMBL:AL662820 xref: EMBL:AL662827 xref: EMBL:BC018541 xref: EMBL:BX248088 xref: EMBL:CR759817 xref: EMBL:Z97183 xref: EMBL:Z97184 xref: HGNC:HGNC:13085 xref: UniGene:Hs.206770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054415 ! ZBT22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020549 name: ZBTB24_human def: "Zinc finger and BTB domain-containing protein 24 gene" [UniProtKB:O43167] synonym: "KIAA0441" EXACT [UniProtKB:O43167] synonym: "ZNF450" EXACT [UniProtKB:O43167] xref: EMBL:AB007901 xref: EMBL:AL109947 xref: EMBL:BC036731 xref: EMBL:BC117374 xref: EMBL:BC117376 xref: HGNC:HGNC:21143 xref: UniGene:Hs.409876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054453 ! ZBT24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020550 name: ZBTB25_human def: "Zinc finger and BTB domain-containing protein 25 gene" [UniProtKB:P24278] synonym: "KUP" EXACT [UniProtKB:P24278] synonym: "ZNF46" EXACT [UniProtKB:P24278] xref: EMBL:BC035804 xref: EMBL:X16576 xref: HGNC:HGNC:13112 xref: UniGene:Hs.654571 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055169 ! ZBT25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020551 name: ZBTB26_human def: "Zinc finger and BTB domain-containing protein 26 gene" [UniProtKB:Q9HCK0] synonym: "KIAA1572" EXACT [UniProtKB:Q9HCK0] synonym: "ZNF481" EXACT [UniProtKB:Q9HCK0] xref: EMBL:AB046792 xref: EMBL:AF323460 xref: EMBL:BC018748 xref: HGNC:HGNC:23383 xref: UniGene:Hs.5638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058809 ! ZBT26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020552 name: ZBTB32_human def: "Zinc finger and BTB domain-containing protein 32 gene" [UniProtKB:Q9Y2Y4] synonym: "FAZF" EXACT [UniProtKB:Q9Y2Y4] synonym: "TZFP" EXACT [UniProtKB:Q9Y2Y4] xref: EMBL:AF130255 xref: EMBL:AF165097 xref: EMBL:BC017700 xref: HGNC:HGNC:16763 xref: UniGene:Hs.99430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059324 ! ZBT32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020553 name: ZBTB34_human def: "Zinc finger and BTB domain-containing protein 34 gene" [UniProtKB:Q8NCN2] synonym: "KIAA1993" EXACT [UniProtKB:Q8NCN2] xref: EMBL:AB082524 xref: EMBL:AL354944 xref: EMBL:DQ227306 xref: HGNC:HGNC:31446 xref: UniGene:Hs.177633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057571 ! ZBT34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020554 name: ZBTB37_human def: "Zinc finger and BTB domain-containing protein 37 gene" [UniProtKB:Q5TC79] xref: EMBL:AK057310 xref: EMBL:AL136170 xref: EMBL:BC003116 xref: EMBL:BC006315 xref: HGNC:HGNC:28365 xref: UniGene:Hs.668497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056610 ! ZBT37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020555 name: ZBTB38_human def: "Zinc finger and BTB domain-containing protein 38 gene" [UniProtKB:Q8NAP3] xref: EMBL:AC010184 xref: EMBL:AK092355 xref: HGNC:HGNC:26636 xref: UniGene:Hs.518301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057549 ! ZBT38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020556 name: ZBTB39_human def: "Zinc finger and BTB domain-containing protein 39 gene" [UniProtKB:O15060] synonym: "KIAA0352" EXACT [UniProtKB:O15060] xref: EMBL:AB002350 xref: HGNC:HGNC:29014 xref: UniGene:Hs.591025 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054401 ! ZBT39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020557 name: ZBTB41_human def: "Zinc finger and BTB domain-containing protein 41 gene" [UniProtKB:Q5SVQ8] synonym: "FRBZ1" EXACT [UniProtKB:Q5SVQ8] xref: EMBL:AK128549 xref: EMBL:AL356315 xref: EMBL:AL627208 xref: EMBL:AY163816 xref: EMBL:AY336933 xref: EMBL:BX640886 xref: HGNC:HGNC:24819 xref: UniGene:Hs.529439 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056545 ! ZBT41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020558 name: ZBTB43_human def: "Zinc finger and BTB domain-containing protein 43 gene" [UniProtKB:O43298] synonym: "KIAA0414" EXACT [UniProtKB:O43298] synonym: "ZBTB22B" EXACT [UniProtKB:O43298] synonym: "ZNF297B" EXACT [UniProtKB:O43298] xref: EMBL:AB007874 xref: EMBL:AF049907 xref: EMBL:BC008828 xref: HGNC:HGNC:17908 xref: UniGene:Hs.591903 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054468 ! ZBT43_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020559 name: ZBTB44_human def: "Zinc finger and BTB domain-containing protein 44 gene" [UniProtKB:Q8NCP5] synonym: "BTBD15" EXACT [UniProtKB:Q8NCP5] xref: EMBL:BC030580 xref: EMBL:BC049375 xref: EMBL:BC050723 xref: EMBL:BC071729 xref: HGNC:HGNC:25001 xref: UniGene:Hs.178499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057572 ! ZBT44_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020560 name: ZBTB45_human def: "Zinc finger and BTB domain-containing protein 45 gene" [UniProtKB:Q96K62] synonym: "ZNF499" EXACT [UniProtKB:Q96K62] xref: EMBL:AK027392 xref: EMBL:BC024738 xref: HGNC:HGNC:23715 xref: UniGene:Hs.515662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058252 ! ZBT45_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020561 name: ZBTB46_human def: "Zinc finger and BTB domain-containing protein 46 gene" [UniProtKB:Q86UZ6] synonym: "BTBD4" EXACT [UniProtKB:Q86UZ6] synonym: "ZNF340" EXACT [UniProtKB:Q86UZ6] xref: EMBL:AL121845 xref: EMBL:BC052269 xref: EMBL:BC073800 xref: HGNC:HGNC:16094 xref: UniGene:Hs.585028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057259 ! ZBT46_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020562 name: ZBTB47_human def: "Zinc finger and BTB domain-containing protein 47 gene" [UniProtKB:Q9UFB7] synonym: "KIAA1190" EXACT [UniProtKB:Q9UFB7] synonym: "ZNF651" EXACT [UniProtKB:Q9UFB7] xref: EMBL:AB033016 xref: EMBL:AL133062 xref: EMBL:BC021855 xref: HGNC:HGNC:26955 xref: UniGene:Hs.409561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059114 ! ZBT47_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020563 name: ZBTB48_human def: "Zinc finger and BTB domain-containing protein 48 gene" [UniProtKB:P10074] synonym: "HKR3" EXACT [UniProtKB:P10074] xref: EMBL:AL591866 xref: EMBL:BC013573 xref: EMBL:L16896 xref: EMBL:M20677 xref: EMBL:U45324 xref: EMBL:U45325 xref: HGNC:HGNC:4930 xref: UniGene:Hs.502330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054968 ! ZBT48_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020564 name: ZBTB7A_human def: "Zinc finger and BTB domain-containing protein 7A gene" [UniProtKB:O95365] synonym: "FBI1" EXACT [UniProtKB:O95365] synonym: "LRF" EXACT [UniProtKB:O95365] synonym: "ZBTB7" EXACT [UniProtKB:O95365] xref: EMBL:AF000561 xref: EMBL:AF097916 xref: EMBL:BC084568 xref: EMBL:BC113511 xref: HGNC:HGNC:18078 xref: UniGene:Hs.591384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054751 ! ZBT7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020565 name: ZBTB7B_human def: "Zinc finger and BTB domain-containing protein 7B gene" [UniProtKB:O15156] synonym: "ZBTB15" EXACT [UniProtKB:O15156] synonym: "ZFP67" EXACT [UniProtKB:O15156] xref: EMBL:AF007833 xref: EMBL:AL451085 xref: EMBL:BC012070 xref: EMBL:CR749303 xref: HGNC:HGNC:18668 xref: UniGene:Hs.505855 xref: UniGene:Hs.700874 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054411 ! ZBT7B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020566 name: ZBTB1_human def: "Zinc finger and BTB domain-containing protein 1 gene" [UniProtKB:Q9Y2K1] synonym: "KIAA0997" EXACT [UniProtKB:Q9Y2K1] xref: EMBL:AB023214 xref: EMBL:BC050719 xref: EMBL:BX248777 xref: HGNC:HGNC:20259 xref: UniGene:Hs.655536 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059309 ! ZBTB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020567 name: ZBTB2_human def: "Zinc finger and BTB domain-containing protein 2 gene" [UniProtKB:Q8N680] synonym: "KIAA1483" EXACT [UniProtKB:Q8N680] synonym: "ZNF437" EXACT [UniProtKB:Q8N680] xref: EMBL:AB040916 xref: EMBL:AL590413 xref: EMBL:BC020172 xref: HGNC:HGNC:20868 xref: UniGene:Hs.520073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057484 ! ZBTB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020568 name: ZBTB3_human def: "Zinc finger and BTB domain-containing protein 3 gene" [UniProtKB:Q9H5J0] xref: EMBL:AK027045 xref: EMBL:BC025249 xref: HGNC:HGNC:22918 xref: UniGene:Hs.147554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058727 ! ZBTB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020569 name: ZBTB5_human def: "Zinc finger and BTB domain-containing protein 5 gene" [UniProtKB:O15062] synonym: "KIAA0354" EXACT [UniProtKB:O15062] xref: EMBL:AB002352 xref: EMBL:BC010007 xref: HGNC:HGNC:23836 xref: UniGene:Hs.161276 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054402 ! ZBTB5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020570 name: ZBTB6_human def: "Zinc finger and BTB domain-containing protein 6 gene" [UniProtKB:Q15916] synonym: "ZID" EXACT [UniProtKB:Q15916] synonym: "ZNF482" EXACT [UniProtKB:Q15916] xref: EMBL:BC037282 xref: EMBL:X82018 xref: HGNC:HGNC:16764 xref: UniGene:Hs.654596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056119 ! ZBTB6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020571 name: ZBTB8_human def: "Zinc finger and BTB domain-containing protein 8 gene" [UniProtKB:Q8NAP8] xref: EMBL:AK074546 xref: EMBL:AK092326 xref: EMBL:AL033529 xref: EMBL:AL356986 xref: EMBL:BC015239 xref: EMBL:CH471059 xref: HGNC:HGNC:24172 xref: UniGene:Hs.546479 xref: UniGene:Hs.647658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057550 ! ZBTB8_HUMAN relationship: codes_for CCO:B0062820 ! Q96BR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020572 name: ZBTB9_human def: "Zinc finger and BTB domain-containing protein 9 gene" [UniProtKB:Q96C00] xref: EMBL:BC014978 xref: HGNC:HGNC:28323 xref: UniGene:Hs.591805 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058173 ! ZBTB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020573 name: ZC3H12A_human def: "Zinc finger CCCH domain-containing protein 12A gene" [UniProtKB:Q5D1E8] synonym: "MCPIP" EXACT [UniProtKB:Q5D1E8] synonym: "MCPIP1" EXACT [UniProtKB:Q5D1E8] xref: EMBL:AK026884 xref: EMBL:AL034379 xref: EMBL:AL449284 xref: EMBL:AY920403 xref: EMBL:BC005001 xref: EMBL:CH471059 xref: EMBL:CR457364 xref: HGNC:HGNC:26259 xref: UniGene:Hs.656294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056421 ! ZC12A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020574 name: ZDHHC13_human def: "Probable palmitoyltransferase ZDHHC13 gene" [UniProtKB:Q8IUH4] synonym: "HIP14L" EXACT [UniProtKB:Q8IUH4] synonym: "HIP3RP" EXACT [UniProtKB:Q8IUH4] xref: EMBL:AB024495 xref: EMBL:AB097014 xref: EMBL:AB097027 xref: EMBL:AK001714 xref: EMBL:AK001831 xref: EMBL:BC036020 xref: EMBL:BC050690 xref: EMBL:BC056152 xref: HGNC:HGNC:18413 xref: UniGene:Hs.188569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057323 ! ZDH13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020575 name: ZDHHC17_human def: "Palmitoyltransferase ZDHHC17 gene" [UniProtKB:Q8IUH5] synonym: "HIP14" EXACT [UniProtKB:Q8IUH5] synonym: "HIP3" EXACT [UniProtKB:Q8IUH5] synonym: "HSPC294" EXACT [UniProtKB:Q8IUH5] synonym: "HYPH" EXACT [UniProtKB:Q8IUH5] synonym: "KIAA0946" EXACT [UniProtKB:Q8IUH5] xref: EMBL:AB023163 xref: EMBL:AB024494 xref: EMBL:AB097013 xref: EMBL:AB097035 xref: EMBL:AF049612 xref: EMBL:AF161412 xref: EMBL:BC030990 xref: EMBL:BC050324 xref: HGNC:HGNC:18412 xref: UniGene:Hs.4014 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057324 ! ZDH17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020576 name: ZEB1_human def: "Zinc finger E-box-binding homeobox 1 gene" [UniProtKB:P37275] synonym: "AREB6" EXACT [UniProtKB:P37275] synonym: "TCF8" EXACT [UniProtKB:P37275] xref: EMBL:AL117340 xref: EMBL:AL158080 xref: EMBL:AL161935 xref: EMBL:AL355148 xref: EMBL:BC112392 xref: EMBL:CH471072 xref: EMBL:D15050 xref: EMBL:M81699 xref: EMBL:U12170 xref: HGNC:HGNC:11642 xref: UniGene:Hs.124503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055317 ! ZEB1_HUMAN relationship: codes_for CCO:B0056203 ! Q2KJ05_HUMAN relationship: codes_for CCO:B0056672 ! Q5VZ84_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020577 name: ZEB2_human def: "Zinc finger E-box-binding homeobox 2 gene" [UniProtKB:O60315] synonym: "HRIHFB2411" EXACT [UniProtKB:O60315] synonym: "KIAA0569" EXACT [UniProtKB:O60315] synonym: "SIP1" EXACT [UniProtKB:O60315] synonym: "ZFHX1B" EXACT [UniProtKB:O60315] synonym: "ZFX1B" EXACT [UniProtKB:O60315] xref: EMBL:AB011141 xref: EMBL:AB015341 xref: EMBL:AB056507 xref: EMBL:AY029472 xref: EMBL:BC127102 xref: HGNC:HGNC:14881 xref: UniGene:Hs.34871 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054546 ! ZEB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020578 name: HIVEP2_human def: "Transcription factor HIVEP2 gene" [UniProtKB:P31629] xref: EMBL:AF153836 xref: EMBL:AL023584 xref: EMBL:M60119 xref: EMBL:M61744 xref: EMBL:X65644 xref: HGNC:HGNC:4921 xref: UniGene:Hs.510172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055245 ! ZEP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020579 name: HIVEP3_human def: "Transcription factor HIVEP3 gene" [UniProtKB:Q5T1R4] synonym: "KBP1" EXACT [UniProtKB:Q5T1R4] synonym: "KIAA1555" EXACT [UniProtKB:Q5T1R4] synonym: "KRC" EXACT [UniProtKB:Q5T1R4] synonym: "ZAS3" EXACT [UniProtKB:Q5T1R4] xref: EMBL:AB046775 xref: EMBL:AF278765 xref: EMBL:AL445933 xref: EMBL:BC152563 xref: HGNC:HGNC:13561 xref: UniGene:Hs.591503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056564 ! ZEP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020580 name: ZFP106_human def: "Zinc finger protein 106 homolog gene" [UniProtKB:Q9H2Y7] synonym: "SH3BP3" EXACT [UniProtKB:Q9H2Y7] synonym: "ZNF474" EXACT [UniProtKB:Q9H2Y7] xref: EMBL:AF205632 xref: EMBL:AF209502 xref: EMBL:AK024726 xref: EMBL:AK057410 xref: EMBL:AL831983 xref: EMBL:AL832014 xref: EMBL:AL832352 xref: EMBL:AL832455 xref: EMBL:AL833301 xref: EMBL:BC058023 xref: EMBL:BC070244 xref: HGNC:HGNC:23240 xref: UniGene:Hs.511143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058692 ! ZF106_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020581 name: ZFP161_human def: "Zinc finger protein 161 homolog gene" [UniProtKB:O43829] synonym: "ZBTB14" EXACT [UniProtKB:O43829] xref: EMBL:BC110519 xref: EMBL:D89859 xref: EMBL:Y12726 xref: HGNC:HGNC:12860 xref: UniGene:Hs.592340 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054523 ! ZF161_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020582 name: ZFHX2_human def: "Zinc finger homeobox protein 2 gene" [UniProtKB:Q9C0A1] synonym: "KIAA1762" EXACT [UniProtKB:Q9C0A1] xref: EMBL:AB051549 xref: HGNC:HGNC:20152 xref: UniGene:Hs.525247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058615 ! ZFHX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020583 name: ZFHX3_human def: "Zinc finger homeobox protein 3 gene" [UniProtKB:Q15911] synonym: "ATBF1" EXACT [UniProtKB:Q15911] xref: EMBL:AC002044 xref: EMBL:AC004943 xref: EMBL:AC132068 xref: EMBL:D10250 xref: EMBL:L32832 xref: HGNC:HGNC:777 xref: UniGene:Hs.652666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056118 ! ZFHX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020584 name: ZFHX4_human def: "Zinc finger homeobox protein 4 gene" [UniProtKB:Q86UP3] xref: EMBL:AB083343 xref: EMBL:AK131408 xref: EMBL:AY260762 xref: HGNC:HGNC:30939 xref: UniGene:Hs.458973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057249 ! ZFHX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020585 name: ZFP14_human def: "Zinc finger protein 14 homolog gene" [UniProtKB:Q9HCL3] synonym: "KIAA1559" EXACT [UniProtKB:Q9HCL3] synonym: "ZNF531" EXACT [UniProtKB:Q9HCL3] xref: EMBL:AB046779 xref: EMBL:AC092296 xref: HGNC:HGNC:29312 xref: UniGene:Hs.35524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054075 ! A8MW73_HUMAN relationship: codes_for CCO:B0058811 ! ZFP14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020586 name: ZFP1_human def: "Zinc finger protein 1 homolog gene" [UniProtKB:Q6P2D0] xref: EMBL:AK094761 xref: EMBL:BC033774 xref: EMBL:BC064604 xref: HGNC:HGNC:23328 xref: UniGene:Hs.388813 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056883 ! ZFP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020587 name: ZFP28_human def: "Zinc finger protein 28 homolog gene" [UniProtKB:Q8NHY6] synonym: "KIAA1431" EXACT [UniProtKB:Q8NHY6] xref: EMBL:AB037852 xref: EMBL:AC007228 xref: EMBL:AF226995 xref: EMBL:AF507045 xref: EMBL:BC028416 xref: EMBL:BC099903 xref: EMBL:BC127003 xref: EMBL:CH471135 xref: HGNC:HGNC:17801 xref: UniGene:Hs.14794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057876 ! Q8NHU8_HUMAN relationship: codes_for CCO:B0057879 ! ZFP28_HUMAN relationship: codes_for CCO:B0059279 ! Q9UQD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020588 name: ZFP2_human def: "Zinc finger protein 2 homolog gene" [UniProtKB:Q6ZN57] xref: EMBL:AK025281 xref: EMBL:AK131367 xref: EMBL:BC132779 xref: EMBL:BC132781 xref: HGNC:HGNC:26138 xref: UniGene:Hs.654533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057013 ! ZFP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020589 name: ZFP30_human def: "Zinc finger protein 30 homolog gene" [UniProtKB:Q9Y2G7] synonym: "KIAA0961" EXACT [UniProtKB:Q9Y2G7] synonym: "ZNF745" EXACT [UniProtKB:Q9Y2G7] xref: EMBL:AB023178 xref: EMBL:BC041087 xref: HGNC:HGNC:29555 xref: UniGene:Hs.116622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059304 ! ZFP30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020590 name: ZFP3_human def: "Zinc finger protein 3 homolog gene" [UniProtKB:Q96NJ6] xref: EMBL:AK055288 xref: HGNC:HGNC:12861 xref: UniGene:Hs.48832 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058307 ! ZFP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020591 name: ZFP41_human def: "Zinc finger protein 41 homolog gene" [UniProtKB:Q8N8Y5] xref: EMBL:AK096024 xref: EMBL:BC034608 xref: HGNC:HGNC:26786 xref: UniGene:Hs.668016 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057528 ! ZFP41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020592 name: ZFP57_human def: "Zinc finger protein 57 homolog gene" [UniProtKB:Q9NU63] synonym: "C6orf40" EXACT [UniProtKB:Q9NU63] synonym: "ZNF698" EXACT [UniProtKB:Q9NU63] xref: EMBL:AL050328 xref: EMBL:AL645936 xref: EMBL:AL669813 xref: EMBL:AL929591 xref: EMBL:BX120002 xref: HGNC:HGNC:18791 xref: UniGene:Hs.156326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058926 ! ZFP57_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020593 name: ZFP62_human def: "Zinc finger protein 62 homolog gene" [UniProtKB:Q8NB50] xref: EMBL:AK091550 xref: EMBL:AL832408 xref: HGNC:HGNC:23241 xref: UniGene:Hs.509227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017875 ! ZFP62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020594 name: ZFP90_human def: "Zinc finger protein 90 homolog gene" [UniProtKB:Q8TF47] synonym: "KIAA1954" EXACT [UniProtKB:Q8TF47] xref: EMBL:AB075834 xref: EMBL:AK056596 xref: EMBL:AX721106 xref: EMBL:BC033165 xref: EMBL:BC040486 xref: HGNC:HGNC:23329 xref: UniGene:Hs.461074 xref: UniGene:Hs.654250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057964 ! ZFP90_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020595 name: ZFP91_human def: "Zinc finger protein 91 homolog gene" [UniProtKB:Q96JP5] synonym: "FKSG11" EXACT [UniProtKB:Q96JP5] xref: EMBL:AB056107 xref: EMBL:AB057443 xref: EMBL:AF310246 xref: EMBL:AP001350 xref: EMBL:BC051743 xref: EMBL:CH471076 xref: HGNC:HGNC:14983 xref: UniGene:Hs.524920 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058247 ! ZFP91_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020596 name: ZFP92_human def: "Zinc finger protein 92 homolog gene" [UniProtKB:A6NM28] xref: EMBL:DR731275 xref: EMBL:U82695 xref: HGNC:HGNC:12865 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053903 ! ZFP92_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020597 name: ZFPL1_human def: "Zinc finger protein-like 1 gene" [UniProtKB:O95159] xref: EMBL:AF001891 xref: EMBL:AF030291 xref: EMBL:AF043611 xref: EMBL:AK291964 xref: EMBL:AP003068 xref: EMBL:BC012530 xref: EMBL:BC012814 xref: EMBL:CH471076 xref: HGNC:HGNC:12868 xref: UniGene:Hs.656314 xref: UniGene:Hs.98170 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054731 ! ZFPL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020598 name: ZFX_human def: "Zinc finger X-chromosomal protein gene" [UniProtKB:P17010] xref: EMBL:AF045779 xref: EMBL:AF045780 xref: EMBL:AF045781 xref: EMBL:AF454950 xref: EMBL:AF505619 xref: EMBL:M26946 xref: EMBL:M30608 xref: EMBL:X59738 xref: EMBL:X59739 xref: EMBL:X59740 xref: HGNC:HGNC:12869 xref: UniGene:Hs.336681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055062 ! ZFX_HUMAN relationship: codes_for CCO:B0057880 ! Q8NHZ1_HUMAN relationship: codes_for CCO:B0058014 ! Q8WXB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020599 name: ZFYVE16_human def: "Zinc finger FYVE domain-containing protein 16 gene" [UniProtKB:Q7Z3T8] synonym: "KIAA0305" EXACT [UniProtKB:Q7Z3T8] xref: EMBL:AB002303 xref: EMBL:AF434817 xref: EMBL:AL833087 xref: EMBL:BC030808 xref: EMBL:BC032227 xref: EMBL:BX537424 xref: HGNC:HGNC:20756 xref: UniGene:Hs.482660 xref: UniGene:Hs.660410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057155 ! ZFY16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020600 name: ZFYVE9_human def: "Zinc finger FYVE domain-containing protein 9 gene" [UniProtKB:O95405] synonym: "MADHIP" EXACT [UniProtKB:O95405] synonym: "SARA" EXACT [UniProtKB:O95405] synonym: "SMADIP" EXACT [UniProtKB:O95405] xref: EMBL:AF104304 xref: EMBL:AF130419 xref: EMBL:AF130420 xref: EMBL:BC032680 xref: HGNC:HGNC:6775 xref: UniGene:Hs.532345 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054758 ! ZFYV9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020601 name: ZFY_human def: "Zinc finger Y-chromosomal protein gene" [UniProtKB:P08048] xref: EMBL:AC006157 xref: EMBL:AF114156 xref: EMBL:BC114526 xref: EMBL:BC114960 xref: EMBL:L10393 xref: EMBL:M30607 xref: EMBL:X15470 xref: HGNC:HGNC:12870 xref: UniGene:Hs.336681 xref: UniGene:Hs.522845 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054918 ! ZFY_HUMAN relationship: codes_for CCO:B0056197 ! Q24JR0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020602 name: ZHX2_human def: "Zinc fingers and homeoboxes protein 2 gene" [UniProtKB:Q9Y6X8] synonym: "AFR1" EXACT [UniProtKB:Q9Y6X8] synonym: "KIAA0854" EXACT [UniProtKB:Q9Y6X8] synonym: "RAF" EXACT [UniProtKB:Q9Y6X8] xref: EMBL:AB020661 xref: EMBL:AB083653 xref: EMBL:BC042145 xref: HGNC:HGNC:18513 xref: UniGene:Hs.377090 xref: UniGene:Hs.658443 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022038 ! ZHX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020603 name: ZHX3_human def: "Zinc fingers and homeoboxes protein 3 gene" [UniProtKB:Q9H4I2] synonym: "KIAA0395" EXACT [UniProtKB:Q9H4I2] synonym: "TIX1" EXACT [UniProtKB:Q9H4I2] xref: EMBL:AB007855 xref: EMBL:AB081948 xref: EMBL:AL022394 xref: EMBL:BC068569 xref: HGNC:HGNC:15935 xref: UniGene:Hs.380133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022040 ! ZHX3_HUMAN relationship: codes_for CCO:B0022042 ! Q6NUJ7_HUMAN relationship: codes_for CCO:B0022045 ! Q5JZ70_HUMAN relationship: codes_for CCO:B0022046 ! Q5JZ69_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020604 name: ZIC1_human def: "Zinc finger protein ZIC 1 gene" [UniProtKB:Q15915] synonym: "ZIC" EXACT [UniProtKB:Q15915] xref: EMBL:BC104848 xref: EMBL:BC104850 xref: EMBL:CH471052 xref: EMBL:D76435 xref: HGNC:HGNC:12872 xref: UniGene:Hs.598590 xref: UniGene:Hs.647962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024799 ! ZIC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020605 name: ZIC3_human def: "Zinc finger protein ZIC 3 gene" [UniProtKB:O60481] xref: EMBL:AF028706 xref: EMBL:AL035443 xref: EMBL:BC113393 xref: EMBL:BC113395 xref: HGNC:HGNC:12874 xref: UniGene:Hs.111227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024794 ! ZIC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020606 name: ZIM2_human def: "Zinc finger imprinted 2 gene" [UniProtKB:Q9NZV7] xref: EMBL:AF166122 xref: EMBL:BC104876 xref: EMBL:BC104878 xref: HGNC:HGNC:12875 xref: UniGene:Hs.201776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059021 ! ZIM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020607 name: ZIM3_human def: "Zinc finger imprinted 3 gene" [UniProtKB:Q96PE6] xref: EMBL:AF365931 xref: EMBL:BC114446 xref: EMBL:BC114503 xref: HGNC:HGNC:16366 xref: UniGene:Hs.348622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058332 ! ZIM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020608 name: ZKSCAN1_human def: "Zinc finger protein with KRAB and SCAN domains 1 gene" [UniProtKB:P17029] synonym: "KOX18" EXACT [UniProtKB:P17029] synonym: "ZNF139" EXACT [UniProtKB:P17029] synonym: "ZNF36" EXACT [UniProtKB:P17029] xref: EMBL:AK074116 xref: EMBL:BC022378 xref: EMBL:BC112224 xref: EMBL:BC113697 xref: EMBL:BX640646 xref: EMBL:U09848 xref: EMBL:X52349 xref: HGNC:HGNC:13101 xref: UniGene:Hs.615360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055073 ! ZKSC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020609 name: ZKSCAN2_human def: "Zinc finger protein with KRAB and SCAN domains 2 gene" [UniProtKB:Q63HK3] synonym: "ZNF694" EXACT [UniProtKB:Q63HK3] xref: EMBL:AK131342 xref: EMBL:BX648785 xref: HGNC:HGNC:25677 xref: UniGene:Hs.513451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056686 ! ZKSC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020610 name: ZKSCAN3_human def: "Zinc finger protein with KRAB and SCAN domains 3 gene" [UniProtKB:Q9BRR0] synonym: "ZFP47" EXACT [UniProtKB:Q9BRR0] synonym: "ZNF306" EXACT [UniProtKB:Q9BRR0] synonym: "ZNF309" EXACT [UniProtKB:Q9BRR0] synonym: "ZSCAN13" EXACT [UniProtKB:Q9BRR0] xref: EMBL:AL021997 xref: EMBL:AL358785 xref: EMBL:BC006118 xref: EMBL:BT007427 xref: EMBL:U71601 xref: HGNC:HGNC:13853 xref: UniGene:Hs.485004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058495 ! ZKSC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020611 name: ZKSCAN4_human def: "Zinc finger protein with KRAB and SCAN domains 4 gene" [UniProtKB:Q969J2] synonym: "ZNF307" EXACT [UniProtKB:Q969J2] xref: EMBL:AL022393 xref: EMBL:AY781778 xref: EMBL:BC014031 xref: EMBL:CH471081 xref: HGNC:HGNC:13854 xref: UniGene:Hs.44720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053799 ! A6NDX7_HUMAN relationship: codes_for CCO:B0058133 ! ZKSC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020612 name: ZKSCAN5_human def: "Zinc finger protein with KRAB and SCAN domains 5 gene" [UniProtKB:Q9Y2L8] synonym: "KIAA1015" EXACT [UniProtKB:Q9Y2L8] synonym: "ZFP95" EXACT [UniProtKB:Q9Y2L8] xref: EMBL:AB023232 xref: EMBL:AF170025 xref: HGNC:HGNC:12867 xref: UniGene:Hs.110839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059310 ! ZKSC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020613 name: ZMAT3_human def: "Zinc finger matrin-type protein 3 gene" [UniProtKB:Q9HA38] synonym: "PAG608" EXACT [UniProtKB:Q9HA38] synonym: "WIG1" EXACT [UniProtKB:Q9HA38] xref: EMBL:AF355465 xref: EMBL:AK022358 xref: EMBL:AY037945 xref: EMBL:BC002896 xref: EMBL:CH471052 xref: HGNC:HGNC:29983 xref: UniGene:Hs.386299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058759 ! ZMAT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020614 name: ZMIZ1_human def: "Zinc finger MIZ domain-containing protein 1 gene" [UniProtKB:Q9ULJ6] synonym: "KIAA1224" EXACT [UniProtKB:Q9ULJ6] synonym: "RAI17" EXACT [UniProtKB:Q9ULJ6] synonym: "ZIMP10" EXACT [UniProtKB:Q9ULJ6] xref: EMBL:AB033050 xref: EMBL:AY235683 xref: HGNC:HGNC:16493 xref: UniGene:Hs.193118 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059227 ! ZMIZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020615 name: ZMYM2_human def: "Zinc finger MYM-type protein 2 gene" [UniProtKB:Q9UBW7] synonym: "FIM" EXACT [UniProtKB:Q9UBW7] synonym: "RAMP" EXACT [UniProtKB:Q9UBW7] synonym: "ZNF198" EXACT [UniProtKB:Q9UBW7] xref: EMBL:AF012126 xref: EMBL:AF035374 xref: EMBL:AF060181 xref: EMBL:AJ007676 xref: EMBL:AJ007677 xref: EMBL:AJ007678 xref: EMBL:AJ007679 xref: EMBL:AJ007680 xref: EMBL:AJ007681 xref: EMBL:AJ007682 xref: EMBL:AJ007683 xref: EMBL:AJ007684 xref: EMBL:AJ007685 xref: EMBL:AJ007686 xref: EMBL:AJ007687 xref: EMBL:AJ007688 xref: EMBL:AJ007689 xref: EMBL:AJ007690 xref: EMBL:AJ007691 xref: EMBL:AJ007692 xref: EMBL:AJ007693 xref: EMBL:AJ007694 xref: EMBL:AJ007695 xref: EMBL:AJ007696 xref: EMBL:AJ224901 xref: EMBL:AL137119 xref: EMBL:AL138688 xref: EMBL:BC036372 xref: EMBL:BX647944 xref: EMBL:CH471075 xref: EMBL:Y13472 xref: HGNC:HGNC:12989 xref: UniGene:Hs.644041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059088 ! ZMYM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020616 name: ZNF101_human def: "Zinc finger protein 101 gene" [UniProtKB:Q8IZC7] xref: EMBL:AY149174 xref: EMBL:BC011502 xref: EMBL:BC094808 xref: HGNC:HGNC:12881 xref: UniGene:Hs.631642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056341 ! Q504T0_HUMAN relationship: codes_for CCO:B0057401 ! ZN101_HUMAN relationship: codes_for CCO:B0062951 ! Q96F93_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020617 name: ZNF114_human def: "Zinc finger protein 114 gene" [UniProtKB:Q8NC26] xref: EMBL:AK075062 xref: EMBL:BC125068 xref: EMBL:BC125069 xref: HGNC:HGNC:12894 xref: UniGene:Hs.511883 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057561 ! ZN114_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020618 name: ZNF117_human def: "Zinc finger protein 117 gene" [UniProtKB:Q03924] xref: EMBL:M27879 xref: EMBL:M55422 xref: EMBL:M61867 xref: HGNC:HGNC:12897 xref: UniGene:Hs.250693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055728 ! ZN117_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020619 name: ZNF121_human def: "Zinc finger protein 121 gene" [UniProtKB:P58317] synonym: "ZNF20" EXACT [UniProtKB:P58317] xref: EMBL:AC008759 xref: EMBL:M99593 xref: HGNC:HGNC:12904 xref: UniGene:Hs.501537 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055570 ! ZN121_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020620 name: ZNF124_human def: "Zinc finger protein 124 gene" [UniProtKB:Q15973] xref: EMBL:AL390728 xref: EMBL:BC096349 xref: EMBL:BC096350 xref: EMBL:BC096351 xref: EMBL:BC099661 xref: EMBL:S54641 xref: HGNC:HGNC:12907 xref: UniGene:Hs.421238 xref: UniGene:Hs.655205 xref: UniGene:Hs.700925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056123 ! ZN124_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020621 name: ZNF131_human def: "Zinc finger protein 131 gene" [UniProtKB:P52739] xref: EMBL:AC106800 xref: EMBL:AK057343 xref: EMBL:BC035875 xref: EMBL:U09410 xref: HGNC:HGNC:12915 xref: UniGene:Hs.535804 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055493 ! ZN131_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020622 name: ZNF132_human def: "Zinc finger protein 132 gene" [UniProtKB:P52740] xref: EMBL:AC012313 xref: EMBL:BC109107 xref: EMBL:BC109108 xref: EMBL:CH471135 xref: EMBL:U09411 xref: HGNC:HGNC:12916 xref: UniGene:Hs.156169 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054131 ! A8MYT8_HUMAN relationship: codes_for CCO:B0055494 ! ZN132_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020623 name: ZNF133_human def: "Zinc finger protein 133 gene" [UniProtKB:P52736] synonym: "ZNF150" EXACT [UniProtKB:P52736] xref: EMBL:AL049646 xref: EMBL:BC001887 xref: EMBL:U09366 xref: HGNC:HGNC:12917 xref: UniGene:Hs.472221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055490 ! ZN133_HUMAN relationship: codes_for CCO:B0056500 ! Q5JXV8_HUMAN relationship: codes_for CCO:B0056501 ! Q5JXV9_HUMAN relationship: codes_for CCO:B0056502 ! Q5JXW0_HUMAN relationship: codes_for CCO:B0056503 ! Q5JXW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020624 name: ZNF135_human def: "Zinc finger protein 135 gene" [UniProtKB:P52742] synonym: "ZNF61" EXACT [UniProtKB:P52742] synonym: "ZNF78L1" EXACT [UniProtKB:P52742] xref: EMBL:AK094202 xref: EMBL:AK098011 xref: EMBL:BC046434 xref: EMBL:CH471135 xref: EMBL:U09413 xref: HGNC:HGNC:12919 xref: UniGene:Hs.85863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055495 ! ZN135_HUMAN relationship: codes_for CCO:B0057429 ! Q8N1I7_HUMAN relationship: codes_for CCO:B0057539 ! Q8N9M3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020625 name: ZNF136_human def: "Zinc finger protein 136 gene" [UniProtKB:P52737] xref: EMBL:BC006421 xref: EMBL:U09367 xref: HGNC:HGNC:12920 xref: UniGene:Hs.479874 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055491 ! ZN136_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020626 name: ZNF137_human def: "Zinc finger protein 137 gene" [UniProtKB:P52743] xref: EMBL:BC110456 xref: EMBL:U09414 xref: HGNC:HGNC:12921 xref: UniGene:Hs.373648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055496 ! ZN137_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020627 name: ZNF138_human def: "Zinc finger protein 138 gene" [UniProtKB:P52744] xref: EMBL:AC073349 xref: EMBL:AK055644 xref: EMBL:U09847 xref: HGNC:HGNC:12922 xref: UniGene:Hs.184080 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055497 ! ZN138_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020628 name: ZNF140_human def: "Zinc finger protein 140 gene" [UniProtKB:P52738] xref: EMBL:AC026786 xref: EMBL:AC073911 xref: EMBL:AK122741 xref: EMBL:BC040561 xref: EMBL:CH471218 xref: EMBL:U09368 xref: HGNC:HGNC:12925 xref: UniGene:Hs.181552 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055492 ! ZN140_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020629 name: ZNF141_human def: "Zinc finger protein 141 gene" [UniProtKB:Q15928] synonym: "D4S90" EXACT [UniProtKB:Q15928] xref: EMBL:BC074853 xref: EMBL:L15309 xref: HGNC:HGNC:12926 xref: UniGene:Hs.654355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056120 ! ZN141_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020630 name: ZNF142_human def: "Zinc finger protein 142 gene" [UniProtKB:P52746] synonym: "KIAA0236" EXACT [UniProtKB:P52746] xref: EMBL:AC012510 xref: EMBL:D87073 xref: EMBL:U09849 xref: HGNC:HGNC:12927 xref: UniGene:Hs.657969 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055498 ! ZN142_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020631 name: ZNF143_human def: "Zinc finger protein 143 gene" [UniProtKB:P52747] synonym: "SBF" EXACT [UniProtKB:P52747] xref: EMBL:AF071771 xref: EMBL:BC020219 xref: EMBL:U09850 xref: HGNC:HGNC:12928 xref: UniGene:Hs.523471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055499 ! ZN143_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020632 name: ZNF148_human def: "Zinc finger protein 148 gene" [UniProtKB:Q9UQR1] synonym: "ZBP89" EXACT [UniProtKB:Q9UQR1] xref: EMBL:AF039019 xref: EMBL:AJ236885 xref: EMBL:BC050260 xref: EMBL:U96633 xref: HGNC:HGNC:12933 xref: UniGene:Hs.592591 xref: UniGene:Hs.693585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059285 ! ZN148_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020633 name: ZNF155_human def: "Zinc finger protein 155 gene" [UniProtKB:Q12901] xref: EMBL:AC018725 xref: EMBL:AF187986 xref: EMBL:BC075050 xref: EMBL:BC075051 xref: EMBL:BC126377 xref: EMBL:BC130381 xref: EMBL:U09852 xref: HGNC:HGNC:12940 xref: UniGene:Hs.502127 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055854 ! ZN155_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020634 name: ZNF157_human def: "Zinc finger protein 157 gene" [UniProtKB:P51786] xref: EMBL:AL590223 xref: EMBL:AL591503 xref: EMBL:BC075003 xref: EMBL:U28687 xref: HGNC:HGNC:12942 xref: UniGene:Hs.89897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055478 ! ZN157_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020635 name: ZNF160_human def: "Zinc finger protein 160 gene" [UniProtKB:Q9HCG1] synonym: "KIAA1611" EXACT [UniProtKB:Q9HCG1] xref: EMBL:AB046831 xref: EMBL:AF277623 xref: EMBL:AK024442 xref: EMBL:BC000807 xref: EMBL:BC094880 xref: EMBL:CH471135 xref: EMBL:X78928 xref: HGNC:HGNC:12948 xref: UniGene:Hs.655967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058528 ! Q9BVY9_HUMAN relationship: codes_for CCO:B0058806 ! ZN160_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020636 name: ZNF165_human def: "Zinc finger protein 165 gene" [UniProtKB:P49910] synonym: "ZPF165" EXACT [UniProtKB:P49910] synonym: "ZSCAN7" EXACT [UniProtKB:P49910] xref: EMBL:AL121944 xref: EMBL:BC026092 xref: EMBL:U78722 xref: EMBL:U88084 xref: EMBL:U88085 xref: EMBL:U88086 xref: EMBL:X84801 xref: HGNC:HGNC:12953 xref: UniGene:Hs.535177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055441 ! ZN165_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020637 name: ZNF167_human def: "Zinc finger protein 167 gene" [UniProtKB:Q9P0L1] synonym: "ZKSCAN7" EXACT [UniProtKB:Q9P0L1] synonym: "ZNF448" EXACT [UniProtKB:Q9P0L1] synonym: "ZNF64" EXACT [UniProtKB:Q9P0L1] xref: EMBL:AF154846 xref: EMBL:AY280798 xref: EMBL:BC010555 xref: EMBL:BC063020 xref: HGNC:HGNC:12955 xref: UniGene:Hs.529512 xref: UniGene:Hs.696570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059030 ! ZN167_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020638 name: ZNF169_human def: "Zinc finger protein 169 gene" [UniProtKB:Q14929] xref: EMBL:AL691447 xref: EMBL:BC011947 xref: EMBL:BC019228 xref: EMBL:BC035060 xref: EMBL:BC047702 xref: EMBL:CH471089 xref: EMBL:U28251 xref: HGNC:HGNC:12957 xref: UniGene:Hs.387623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053723 ! A2AGP5_HUMAN relationship: codes_for CCO:B0056025 ! ZN169_HUMAN relationship: codes_for CCO:B0056912 ! Q6PIG1_HUMAN relationship: codes_for CCO:B0056918 ! Q6PJ92_HUMAN relationship: codes_for CCO:B0057207 ! Q7Z761_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020639 name: ZNF174_human def: "Zinc finger protein 174 gene" [UniProtKB:Q15697] synonym: "ZSCAN8" EXACT [UniProtKB:Q15697] xref: EMBL:BC000876 xref: EMBL:BC001161 xref: EMBL:U31248 xref: HGNC:HGNC:12963 xref: UniGene:Hs.155204 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056096 ! ZN174_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020640 name: ZNF177_human def: "Zinc finger protein 177 gene" [UniProtKB:Q13360] xref: EMBL:BC012012 xref: EMBL:U37263 xref: HGNC:HGNC:12966 xref: UniGene:Hs.172979 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055901 ! ZN177_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020641 name: ZNF180_human def: "Zinc finger protein 180 gene" [UniProtKB:Q9UJW8] xref: EMBL:AC069278 xref: EMBL:AF192913 xref: EMBL:BC033642 xref: EMBL:BC113015 xref: EMBL:CH471126 xref: HGNC:HGNC:12970 xref: UniGene:Hs.130683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056376 ! Q58F03_HUMAN relationship: codes_for CCO:B0059179 ! ZN180_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020642 name: ZNF181_human def: "Zinc finger protein 181 gene" [UniProtKB:Q2M3W8] xref: EMBL:BC043228 xref: EMBL:BC104759 xref: HGNC:HGNC:12971 xref: UniGene:Hs.659191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056213 ! ZN181_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020643 name: ZNF182_human def: "Zinc finger protein 182 gene" [UniProtKB:P17025] synonym: "KOX14" EXACT [UniProtKB:P17025] synonym: "ZNF21" EXACT [UniProtKB:P17025] xref: EMBL:AK122874 xref: EMBL:BC106875 xref: EMBL:BC114216 xref: EMBL:CH471164 xref: EMBL:X52345 xref: EMBL:Z98304 xref: HGNC:HGNC:13001 xref: UniGene:Hs.189690 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055070 ! ZN182_HUMAN relationship: codes_for CCO:B0058354 ! Q96QH7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020644 name: ZNF184_human def: "Zinc finger protein 184 gene" [UniProtKB:Q99676] xref: EMBL:AK312804 xref: EMBL:AL021918 xref: EMBL:BC022992 xref: EMBL:U66561 xref: HGNC:HGNC:12975 xref: UniGene:Hs.158174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058437 ! ZN184_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020645 name: ZNF187_human def: "Zinc finger protein 187 gene" [UniProtKB:Q16670] synonym: "ZSCAN26" EXACT [UniProtKB:Q16670] xref: EMBL:AL021997 xref: EMBL:AL832741 xref: EMBL:BC013951 xref: EMBL:BC013962 xref: EMBL:BX537535 xref: EMBL:Z11773 xref: HGNC:HGNC:12978 xref: UniGene:Hs.157883 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056173 ! ZN187_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020646 name: ZNF189_human def: "Zinc finger protein 189 gene" [UniProtKB:O75820] xref: EMBL:AF025770 xref: EMBL:AF025771 xref: EMBL:AF025772 xref: EMBL:AL353621 xref: EMBL:BC092425 xref: EMBL:U75454 xref: EMBL:U95991 xref: EMBL:U95992 xref: HGNC:HGNC:12980 xref: UniGene:Hs.50123 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054671 ! ZN189_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020647 name: ZNF192_human def: "Zinc finger protein 192 gene" [UniProtKB:Q15776] synonym: "ZKSCAN8" EXACT [UniProtKB:Q15776] xref: EMBL:AL358933 xref: EMBL:BC096282 xref: EMBL:BC096283 xref: EMBL:BC096284 xref: EMBL:U57796 xref: EMBL:U88079 xref: EMBL:U88080 xref: HGNC:HGNC:12983 xref: UniGene:Hs.57679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056110 ! ZN192_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020648 name: ZNF193_human def: "Zinc finger protein 193 gene" [UniProtKB:O15535] synonym: "ZSCAN9" EXACT [UniProtKB:O15535] xref: EMBL:AL022393 xref: EMBL:BC010374 xref: EMBL:U62392 xref: EMBL:U88081 xref: EMBL:U88082 xref: HGNC:HGNC:12984 xref: UniGene:Hs.100921 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054446 ! ZN193_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020649 name: ZNF195_human def: "Zinc finger protein 195 gene" [UniProtKB:O14628] synonym: "ZNFP104" EXACT [UniProtKB:O14628] xref: EMBL:AF003540 xref: EMBL:AK290099 xref: EMBL:BC121029 xref: EMBL:CH471158 xref: HGNC:HGNC:12986 xref: UniGene:Hs.386294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054362 ! ZN195_HUMAN relationship: codes_for CCO:B0055821 ! Q0VAJ6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020650 name: ZNF197_human def: "Zinc finger protein 197 gene" [UniProtKB:O14709] synonym: "ZKSCAN9" EXACT [UniProtKB:O14709] synonym: "ZNF166" EXACT [UniProtKB:O14709] xref: EMBL:AF011573 xref: EMBL:BC031209 xref: HGNC:HGNC:12988 xref: UniGene:Hs.157035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021154 ! Q6PIQ2_HUMAN relationship: codes_for CCO:B0054369 ! ZN197_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020651 name: ZNF202_human def: "Zinc finger protein 202 gene" [UniProtKB:O95125] synonym: "ZKSCAN10" EXACT [UniProtKB:O95125] xref: EMBL:AF027218 xref: EMBL:AF027219 xref: EMBL:AJ276177 xref: EMBL:AJ276178 xref: EMBL:AJ276179 xref: EMBL:AJ276180 xref: EMBL:AJ276181 xref: EMBL:AJ276182 xref: EMBL:AL162031 xref: EMBL:BC013382 xref: EMBL:DQ093962 xref: HGNC:HGNC:12994 xref: UniGene:Hs.112556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054725 ! ZN202_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020652 name: ZNF205_human def: "Zinc finger protein 205 gene" [UniProtKB:O95201] synonym: "ZNF210" EXACT [UniProtKB:O95201] xref: EMBL:AC108134 xref: EMBL:AF060865 xref: EMBL:BC002810 xref: EMBL:CH471112 xref: HGNC:HGNC:12996 xref: UniGene:Hs.592088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054735 ! ZN205_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020653 name: ZNF207_human def: "Zinc finger protein 207 gene" [UniProtKB:O43670] xref: EMBL:AF046001 xref: EMBL:BC002372 xref: EMBL:BC008023 xref: HGNC:HGNC:12998 xref: UniGene:Hs.500775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054509 ! ZN207_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020654 name: ZNF208_human def: "Zinc finger protein 208 gene" [UniProtKB:O43345] synonym: "ZNF91L" EXACT [UniProtKB:O43345] xref: EMBL:AC003973 xref: HGNC:HGNC:12999 xref: UniGene:Hs.660982 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054473 ! ZN208_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020655 name: ZNF212_human def: "Zinc finger protein 212 gene" [UniProtKB:Q9UDV6] synonym: "ZNFC150" EXACT [UniProtKB:Q9UDV6] xref: EMBL:AC004890 xref: EMBL:BC022785 xref: EMBL:U38864 xref: HGNC:HGNC:13004 xref: UniGene:Hs.490510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059104 ! ZN212_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020656 name: ZNF213_human def: "Zinc finger protein 213 gene" [UniProtKB:O14771] synonym: "ZKSCAN21" EXACT [UniProtKB:O14771] xref: EMBL:AF017433 xref: EMBL:BC007287 xref: HGNC:HGNC:13005 xref: UniGene:Hs.115284 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054374 ! ZN213_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020657 name: ZNF214_human def: "Zinc finger protein 214 gene" [UniProtKB:Q9UL59] synonym: "BAZ1" EXACT [UniProtKB:Q9UL59] xref: EMBL:AF056617 xref: HGNC:HGNC:13006 xref: UniGene:Hs.445849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059219 ! ZN214_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020658 name: ZNF215_human def: "Zinc finger protein 215 gene" [UniProtKB:Q9UL58] synonym: "BAZ2" EXACT [UniProtKB:Q9UL58] synonym: "ZKSCAN11" EXACT [UniProtKB:Q9UL58] xref: EMBL:AF056618 xref: EMBL:BC014538 xref: HGNC:HGNC:13007 xref: UniGene:Hs.523457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058178 ! Q96C84_HUMAN relationship: codes_for CCO:B0059218 ! ZN215_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020659 name: ZNF217_human def: "Zinc finger protein 217 gene" [UniProtKB:O75362] synonym: "ZABC1" EXACT [UniProtKB:O75362] xref: EMBL:AF041259 xref: EMBL:AL157838 xref: EMBL:BC113427 xref: HGNC:HGNC:13009 xref: UniGene:Hs.155040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054623 ! ZN217_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020660 name: ZNF219_human def: "Zinc finger protein 219 gene" [UniProtKB:Q9P2Y4] xref: EMBL:AB015427 xref: EMBL:BC000694 xref: EMBL:BC036105 xref: HGNC:HGNC:13011 xref: UniGene:Hs.250493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059063 ! ZN219_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020661 name: ZNF221_human def: "Zinc finger protein 221 gene" [UniProtKB:Q9UK13] xref: EMBL:AC035150 xref: EMBL:AF187987 xref: EMBL:BC111981 xref: EMBL:BC113426 xref: HGNC:HGNC:13014 xref: UniGene:Hs.631598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059186 ! ZN221_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020662 name: ZNF222_human def: "Zinc finger protein 222 gene" [UniProtKB:Q9UK12] xref: EMBL:AC067968 xref: EMBL:AF187988 xref: HGNC:HGNC:13015 xref: UniGene:Hs.279840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059185 ! ZN222_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020663 name: ZNF223_human def: "Zinc finger protein 223 gene" [UniProtKB:Q9UK11] xref: EMBL:AF187989 xref: EMBL:AK292327 xref: EMBL:BC022466 xref: HGNC:HGNC:13016 xref: UniGene:Hs.279840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057903 ! Q8TBJ3_HUMAN relationship: codes_for CCO:B0059184 ! ZN223_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020664 name: ZNF224_human def: "Zinc finger protein 224 gene" [UniProtKB:Q9NZL3] synonym: "BMZF2" EXACT [UniProtKB:Q9NZL3] synonym: "KOX22" EXACT [UniProtKB:Q9NZL3] synonym: "ZNF233" EXACT [UniProtKB:Q9NZL3] synonym: "ZNF255" EXACT [UniProtKB:Q9NZL3] synonym: "ZNF27" EXACT [UniProtKB:Q9NZL3] xref: EMBL:AC021092 xref: EMBL:AC084219 xref: EMBL:AC114266 xref: EMBL:AF067164 xref: EMBL:AF187990 xref: EMBL:AY148489 xref: EMBL:BC051902 xref: EMBL:X52353 xref: HGNC:HGNC:13017 xref: UniGene:Hs.585869 xref: UniGene:Hs.590967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059004 ! ZN224_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020665 name: ZNF225_human def: "Zinc finger protein 225 gene" [UniProtKB:Q9UK10] xref: EMBL:AC021092 xref: EMBL:AC074331 xref: EMBL:AF187991 xref: EMBL:AK223477 xref: EMBL:BC108912 xref: HGNC:HGNC:13018 xref: UniGene:Hs.279567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059183 ! ZN225_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020666 name: ZNF226_human def: "Zinc finger protein 226 gene" [UniProtKB:Q9NYT6] xref: EMBL:AC074331 xref: EMBL:AF228418 xref: EMBL:AK023091 xref: EMBL:BC017786 xref: EMBL:BC024197 xref: EMBL:CH471126 xref: HGNC:HGNC:13019 xref: UniGene:Hs.145956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058003 ! Q8WWE6_HUMAN relationship: codes_for CCO:B0058973 ! ZN226_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020667 name: ZNF227_human def: "Zinc finger protein 227 gene" [UniProtKB:Q86WZ6] xref: EMBL:BC047570 xref: HGNC:HGNC:13020 xref: UniGene:Hs.371335 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057282 ! ZN227_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020668 name: ZNF229_human def: "Zinc finger protein 229 gene" [UniProtKB:Q9UJW7] xref: EMBL:AB209357 xref: EMBL:AC084239 xref: EMBL:AF192979 xref: EMBL:AY166791 xref: HGNC:HGNC:13022 xref: UniGene:Hs.48589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059178 ! ZN229_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020669 name: ZNF230_human def: "Zinc finger protein 230 gene" [UniProtKB:Q9UIE0] synonym: "FDZF2" EXACT [UniProtKB:Q9UIE0] xref: EMBL:AC006213 xref: EMBL:AC018725 xref: EMBL:AC067968 xref: EMBL:BC050340 xref: EMBL:BC094708 xref: EMBL:U95044 xref: HGNC:HGNC:13024 xref: UniGene:Hs.193583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054054 ! A8MV38_HUMAN relationship: codes_for CCO:B0059158 ! ZN230_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020670 name: ZNF232_human def: "Zinc finger protein 232 gene" [UniProtKB:Q9UNY5] synonym: "ZSCAN11" EXACT [UniProtKB:Q9UNY5] xref: EMBL:AF080170 xref: EMBL:AF080171 xref: EMBL:BC016039 xref: EMBL:Y15067 xref: HGNC:HGNC:13026 xref: UniGene:Hs.279914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059257 ! ZN232_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020671 name: ZNF233_human def: "Zinc finger protein 233 gene" [UniProtKB:A6NK53] xref: EMBL:AC092477 xref: EMBL:AC138470 xref: EMBL:AK095351 xref: EMBL:AY166792 xref: HGNC:HGNC:30946 xref: UniGene:Hs.466891 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053878 ! ZN233_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020672 name: ZNF234_human def: "Zinc finger protein 234 gene" [UniProtKB:Q14588] synonym: "ZNF269" EXACT [UniProtKB:Q14588] xref: EMBL:AC074331 xref: EMBL:AF228417 xref: EMBL:BC007303 xref: EMBL:X78927 xref: HGNC:HGNC:13027 xref: UniGene:Hs.334586 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056000 ! ZN234_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020673 name: ZNF235_human def: "Zinc finger protein 235 gene" [UniProtKB:Q14590] synonym: "ZFP93" EXACT [UniProtKB:Q14590] synonym: "ZNF270" EXACT [UniProtKB:Q14590] xref: EMBL:AC084239 xref: EMBL:AC092477 xref: EMBL:AC138470 xref: EMBL:AC138473 xref: EMBL:AF027513 xref: EMBL:AF027514 xref: EMBL:AK300317 xref: EMBL:BC117215 xref: EMBL:X78929 xref: HGNC:HGNC:12866 xref: UniGene:Hs.298089 xref: UniGene:Hs.664229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054059 ! A8MVM0_HUMAN relationship: codes_for CCO:B0056001 ! ZN235_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020674 name: ZNF236_human def: "Zinc finger protein 236 gene" [UniProtKB:Q9UL36] xref: EMBL:AF085243 xref: EMBL:AF085244 xref: HGNC:HGNC:13028 xref: UniGene:Hs.189826 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059216 ! ZN236_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020675 name: ZNF238_human def: "Zinc finger protein 238 gene" [UniProtKB:Q99592] synonym: "RP58" EXACT [UniProtKB:Q99592] synonym: "TAZ1" EXACT [UniProtKB:Q99592] synonym: "ZBTB18" EXACT [UniProtKB:Q99592] xref: EMBL:AJ001388 xref: EMBL:AJ223321 xref: EMBL:AL590483 xref: EMBL:BC036677 xref: EMBL:U38896 xref: EMBL:X95072 xref: HGNC:HGNC:13030 xref: UniGene:Hs.69997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058428 ! ZN238_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020676 name: ZNF239_human def: "Zinc finger protein 239 gene" [UniProtKB:Q16600] synonym: "HOK2" EXACT [UniProtKB:Q16600] synonym: "MOK2" EXACT [UniProtKB:Q16600] xref: EMBL:AL450326 xref: EMBL:BC026030 xref: EMBL:X82125 xref: EMBL:X82126 xref: HGNC:HGNC:13031 xref: UniGene:Hs.25040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056157 ! ZN239_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020677 name: ZNF248_human def: "Zinc finger protein 248 gene" [UniProtKB:Q8NDW4] xref: EMBL:AJ245587 xref: EMBL:AJ491695 xref: EMBL:AJ492196 xref: EMBL:AL135791 xref: EMBL:BC021819 xref: EMBL:BC110869 xref: EMBL:BC146820 xref: EMBL:CH471072 xref: HGNC:HGNC:13041 xref: UniGene:Hs.572001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054236 ! B1AL40_HUMAN relationship: codes_for CCO:B0055758 ! Q05CR2_HUMAN relationship: codes_for CCO:B0057582 ! Q8NDV8_HUMAN relationship: codes_for CCO:B0057583 ! ZN248_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020678 name: ZNF250_human def: "Zinc finger protein 250 gene" [UniProtKB:P15622] synonym: "ZNF647" EXACT [UniProtKB:P15622] xref: EMBL:AK095705 xref: EMBL:BC017091 xref: EMBL:BC107579 xref: EMBL:X16282 xref: HGNC:HGNC:13044 xref: UniGene:Hs.532277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055041 ! ZN250_HUMAN relationship: codes_for CCO:B0056244 ! Q3B7J8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020679 name: ZNF251_human def: "Zinc finger protein 251 gene" [UniProtKB:Q9BRH9] xref: EMBL:AF186192 xref: EMBL:AK000435 xref: EMBL:BC006258 xref: EMBL:BC112137 xref: HGNC:HGNC:13045 xref: UniGene:Hs.534516 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058492 ! ZN251_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020680 name: ZNF254_human def: "Zinc finger protein 254 gene" [UniProtKB:O75437] synonym: "BMZF5" EXACT [UniProtKB:O75437] synonym: "ZNF539" EXACT [UniProtKB:O75437] synonym: "ZNF91L" EXACT [UniProtKB:O75437] xref: EMBL:AF054180 xref: EMBL:BC043147 xref: EMBL:BC056243 xref: EMBL:BC139749 xref: EMBL:CH471106 xref: HGNC:HGNC:13047 xref: UniGene:Hs.434406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032352 ! Q7Z2R1_HUMAN relationship: codes_for CCO:B0054635 ! ZN254_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020681 name: ZNF256_human def: "Zinc finger protein 256 gene" [UniProtKB:Q9Y2P7] synonym: "BMZF3" EXACT [UniProtKB:Q9Y2P7] xref: EMBL:AF067165 xref: EMBL:BC001438 xref: HGNC:HGNC:13049 xref: UniGene:Hs.596242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059312 ! ZN256_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020682 name: ZNF257_human def: "Zinc finger protein 257 gene" [UniProtKB:Q9Y2Q1] synonym: "BMZF4" EXACT [UniProtKB:Q9Y2Q1] xref: EMBL:AF070651 xref: HGNC:HGNC:13498 xref: UniGene:Hs.283900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059313 ! ZN257_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020683 name: ZNF264_human def: "Zinc finger protein 264 gene" [UniProtKB:O43296] synonym: "KIAA0412" EXACT [UniProtKB:O43296] xref: EMBL:AB007872 xref: EMBL:AC005261 xref: EMBL:AC025588 xref: HGNC:HGNC:13057 xref: UniGene:Hs.515634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054467 ! ZN264_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020684 name: ZNF266_human def: "Zinc finger protein 266 gene" [UniProtKB:Q14584] synonym: "KIAA2007" EXACT [UniProtKB:Q14584] xref: EMBL:AB095928 xref: EMBL:AK027480 xref: EMBL:AY376240 xref: EMBL:BC017407 xref: EMBL:BC071628 xref: EMBL:BC126255 xref: EMBL:X78924 xref: HGNC:HGNC:13059 xref: UniGene:Hs.656185 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055996 ! ZN266_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020685 name: ZNF267_human def: "Zinc finger protein 267 gene" [UniProtKB:Q14586] xref: EMBL:AF220492 xref: EMBL:BC036367 xref: EMBL:X78925 xref: HGNC:HGNC:13060 xref: UniGene:Hs.460645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055998 ! ZN267_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020686 name: ZNF268_human def: "Zinc finger protein 268 gene" [UniProtKB:Q14587] xref: EMBL:AF317549 xref: EMBL:AF385187 xref: EMBL:X78926 xref: HGNC:HGNC:13061 xref: UniGene:Hs.183291 xref: UniGene:Hs.654533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055999 ! ZN268_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020687 name: ZNF271_human def: "Zinc finger protein 271 gene" [UniProtKB:Q14591] synonym: "ZNFEB" EXACT [UniProtKB:Q14591] xref: EMBL:AF153201 xref: EMBL:AF159567 xref: EMBL:AF373036 xref: EMBL:BC004510 xref: EMBL:BC017710 xref: EMBL:X78930 xref: HGNC:HGNC:13065 xref: UniGene:Hs.314246 xref: UniGene:Hs.682373 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056002 ! ZN271_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020688 name: ZNF274_human def: "Zinc finger protein 274 gene" [UniProtKB:Q96GC6] synonym: "SP2114" EXACT [UniProtKB:Q96GC6] synonym: "ZKSCAN19" EXACT [UniProtKB:Q96GC6] xref: EMBL:AB029149 xref: EMBL:AB029150 xref: EMBL:AF275680 xref: EMBL:AF275681 xref: EMBL:BC009763 xref: EMBL:U71598 xref: HGNC:HGNC:13068 xref: UniGene:Hs.83761 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058214 ! ZN274_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020689 name: ZNF275_human def: "Zinc finger protein 275 gene" [UniProtKB:Q9NSD4] xref: EMBL:U82670 xref: HGNC:HGNC:13069 xref: UniGene:Hs.348963 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058917 ! ZN275_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020690 name: ZNF276_human def: "Zinc finger protein 276 gene" [UniProtKB:Q8N554] synonym: "ZFP276" EXACT [UniProtKB:Q8N554] xref: EMBL:AF354755 xref: EMBL:AF354756 xref: EMBL:AK026482 xref: EMBL:BC032781 xref: EMBL:BC107603 xref: EMBL:BC110348 xref: EMBL:BC111408 xref: HGNC:HGNC:23330 xref: UniGene:Hs.290154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057470 ! ZN276_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020691 name: ZNF281_human def: "Zinc finger protein 281 gene" [UniProtKB:Q9Y2X9] synonym: "GZP1" EXACT [UniProtKB:Q9Y2X9] synonym: "ZBP99" EXACT [UniProtKB:Q9Y2X9] xref: EMBL:AF125158 xref: EMBL:AJ132591 xref: EMBL:AJ132592 xref: EMBL:BC060820 xref: HGNC:HGNC:13075 xref: UniGene:Hs.59757 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059321 ! ZN281_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020692 name: ZNF282_human def: "Zinc finger protein 282 gene" [UniProtKB:Q9UDV7] synonym: "HUB1" EXACT [UniProtKB:Q9UDV7] xref: EMBL:AC004890 xref: EMBL:BC031686 xref: EMBL:BC073805 xref: EMBL:D30612 xref: HGNC:HGNC:13076 xref: UniGene:Hs.657701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055754 ! Q05BY5_HUMAN relationship: codes_for CCO:B0059105 ! ZN282_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020693 name: ZNF283_human def: "Zinc finger protein 283 gene" [UniProtKB:Q8N7M2] xref: EMBL:AK098175 xref: EMBL:AK294852 xref: EMBL:AY166784 xref: EMBL:BC045755 xref: HGNC:HGNC:13077 xref: UniGene:Hs.652513 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056312 ! Q4G0N1_HUMAN relationship: codes_for CCO:B0057504 ! ZN283_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020694 name: ZNF284_human def: "Zinc finger protein 284 gene" [UniProtKB:Q2VY69] synonym: "ZNF284L" EXACT [UniProtKB:Q2VY69] xref: EMBL:AY166789 xref: EMBL:AY458845 xref: HGNC:HGNC:13078 xref: UniGene:Hs.445395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056235 ! ZN284_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020695 name: ZNF287_human def: "Zinc finger protein 287 gene" [UniProtKB:Q9HBT7] synonym: "ZKSCAN13" EXACT [UniProtKB:Q9HBT7] xref: EMBL:AF217227 xref: EMBL:BC101487 xref: EMBL:BC113363 xref: EMBL:CR457194 xref: HGNC:HGNC:13502 xref: UniGene:Hs.99724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058790 ! ZN287_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020696 name: ZNF292_human def: "Zinc finger protein 292 gene" [UniProtKB:O60281] synonym: "KIAA0530" EXACT [UniProtKB:O60281] xref: EMBL:AB011102 xref: EMBL:AK023626 xref: EMBL:AK023712 xref: HGNC:HGNC:18410 xref: UniGene:Hs.590890 xref: UniGene:Hs.656621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054539 ! ZN292_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020697 name: ZNF302_human def: "Zinc finger protein 302 gene" [UniProtKB:Q9NR11] synonym: "ZNF135L" EXACT [UniProtKB:Q9NR11] synonym: "ZNF140L" EXACT [UniProtKB:Q9NR11] xref: EMBL:AF155656 xref: EMBL:AF265236 xref: EMBL:AF326206 xref: EMBL:BC024176 xref: HGNC:HGNC:13848 xref: UniGene:Hs.436350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058882 ! ZN302_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020698 name: ZNF304_human def: "Zinc finger protein 304 gene" [UniProtKB:Q9HCX3] xref: EMBL:AJ276316 xref: EMBL:BC111532 xref: HGNC:HGNC:13505 xref: UniGene:Hs.287374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056224 ! Q2T9G7_HUMAN relationship: codes_for CCO:B0058820 ! ZN304_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020699 name: ZNF311_human def: "Zinc finger protein 311 gene" [UniProtKB:Q5JNZ3] synonym: "ZFP31" EXACT [UniProtKB:Q5JNZ3] xref: EMBL:AL662791 xref: EMBL:AL662865 xref: EMBL:AL929561 xref: EMBL:BX293545 xref: EMBL:U71600 xref: HGNC:HGNC:13847 xref: UniGene:Hs.148218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053729 ! A2BFK5_HUMAN relationship: codes_for CCO:B0056451 ! ZN311_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020700 name: ZNF317_human def: "Zinc finger protein 317 gene" [UniProtKB:Q96PQ6] synonym: "KIAA1588" EXACT [UniProtKB:Q96PQ6] xref: EMBL:AB046808 xref: EMBL:AF148135 xref: EMBL:AF275255 xref: EMBL:AF307096 xref: EMBL:AF307097 xref: HGNC:HGNC:13507 xref: UniGene:Hs.465829 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058342 ! ZN317_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020701 name: ZNF319_human def: "Zinc finger protein 319 gene" [UniProtKB:Q9P2F9] synonym: "KIAA1388" EXACT [UniProtKB:Q9P2F9] xref: EMBL:AB037809 xref: EMBL:BC093919 xref: EMBL:BC101767 xref: HGNC:HGNC:13644 xref: UniGene:Hs.129268 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059057 ! ZN319_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020702 name: ZNF320_human def: "Zinc finger protein 320 gene" [UniProtKB:A2RRD8] xref: EMBL:AC010487 xref: EMBL:AL831902 xref: EMBL:BC131555 xref: HGNC:HGNC:13842 xref: UniGene:Hs.446907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053736 ! ZN320_HUMAN relationship: codes_for CCO:B0053985 ! A8MPQ0_HUMAN relationship: codes_for CCO:B0054074 ! A8MW67_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020703 name: ZNF321_human def: "KRAB domain-containing protein ZNF321 gene" [UniProtKB:Q8N8H1] xref: EMBL:AK096828 xref: EMBL:BC046449 xref: EMBL:BC119627 xref: EMBL:BC119628 xref: EMBL:CR749224 xref: HGNC:HGNC:13827 xref: UniGene:Hs.675715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057520 ! ZN321_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020704 name: ZNF323_human def: "Zinc finger protein 323 gene" [UniProtKB:Q96LW9] synonym: "ZNF310P" EXACT [UniProtKB:Q96LW9] xref: EMBL:AF513019 xref: EMBL:AK057702 xref: EMBL:AL021997 xref: HGNC:HGNC:14097 xref: UniGene:Hs.656413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058277 ! ZN323_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020705 name: ZNF326_human def: "Zinc finger protein 326 gene" [UniProtKB:Q5BKZ1] xref: EMBL:AL161797 xref: EMBL:AL391497 xref: EMBL:BC052645 xref: EMBL:BC053888 xref: EMBL:BC070341 xref: EMBL:BC090866 xref: HGNC:HGNC:14104 xref: UniGene:Hs.306221 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018465 ! ZN326_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020706 name: ZNF329_human def: "Zinc finger protein 329 gene" [UniProtKB:Q86UD4] xref: EMBL:AK022648 xref: EMBL:BC047501 xref: HGNC:HGNC:14209 xref: UniGene:Hs.458377 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057246 ! ZN329_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020707 name: ZNF331_human def: "Zinc finger protein 331 gene" [UniProtKB:Q9NQX6] synonym: "RITA" EXACT [UniProtKB:Q9NQX6] synonym: "ZNF463" EXACT [UniProtKB:Q9NQX6] xref: EMBL:AF251515 xref: EMBL:AF272148 xref: EMBL:BC009433 xref: HGNC:HGNC:15489 xref: UniGene:Hs.185674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058880 ! ZN331_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020708 name: ZNF333_human def: "Zinc finger protein 333 gene" [UniProtKB:Q96JL9] synonym: "KIAA1806" EXACT [UniProtKB:Q96JL9] xref: EMBL:AB058709 xref: EMBL:AF372702 xref: EMBL:AK291471 xref: EMBL:BC064571 xref: HGNC:HGNC:15624 xref: UniGene:Hs.515215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056884 ! Q6P2E6_HUMAN relationship: codes_for CCO:B0058243 ! ZN333_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020709 name: ZNF334_human def: "Zinc finger protein 334 gene" [UniProtKB:Q9HCZ1] xref: EMBL:AK001331 xref: EMBL:AL034424 xref: EMBL:AL354745 xref: EMBL:BC024177 xref: HGNC:HGNC:15806 xref: UniGene:Hs.584933 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058822 ! ZN334_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020710 name: ZNF335_human def: "Zinc finger protein 335 gene" [UniProtKB:Q9H4Z2] xref: EMBL:AF395833 xref: EMBL:AK026157 xref: EMBL:AK296989 xref: EMBL:AL162458 xref: HGNC:HGNC:15807 xref: UniGene:Hs.174193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058721 ! ZN335_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020711 name: ZNF337_human def: "Zinc finger protein 337 gene" [UniProtKB:Q9Y3M9] xref: EMBL:AL031673 xref: EMBL:AL049942 xref: EMBL:BC021298 xref: HGNC:HGNC:15809 xref: UniGene:Hs.633621 xref: UniGene:Hs.661684 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059340 ! ZN337_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020712 name: ZNF33A_human def: "Zinc finger protein 33A gene" [UniProtKB:Q06730] synonym: "KIAA0065" EXACT [UniProtKB:Q06730] synonym: "KOX31" EXACT [UniProtKB:Q06730] synonym: "ZNF11" EXACT [UniProtKB:Q06730] synonym: "ZNF11A" EXACT [UniProtKB:Q06730] synonym: "ZNF33" EXACT [UniProtKB:Q06730] xref: EMBL:AK027057 xref: EMBL:AL117337 xref: EMBL:AL161931 xref: EMBL:AY184389 xref: EMBL:BC126119 xref: EMBL:CH471072 xref: EMBL:D31763 xref: EMBL:X68686 xref: EMBL:X68687 xref: EMBL:X68689 xref: HGNC:HGNC:13096 xref: UniGene:Hs.435774 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053697 ! A0AUX1_HUMAN relationship: codes_for CCO:B0055772 ! ZN33A_HUMAN relationship: codes_for CCO:B0058726 ! Q9H5I4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020713 name: ZNF33B_human def: "Zinc finger protein 33B gene" [UniProtKB:Q06732] synonym: "KOX2" EXACT [UniProtKB:Q06732] synonym: "ZNF11B" EXACT [UniProtKB:Q06732] xref: EMBL:AJ491697 xref: EMBL:AL022345 xref: EMBL:BC048313 xref: EMBL:BC065181 xref: EMBL:X52333 xref: EMBL:X68684 xref: EMBL:X68685 xref: EMBL:X68688 xref: HGNC:HGNC:13097 xref: UniGene:Hs.499453 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055773 ! ZN33B_HUMAN relationship: codes_for CCO:B0056878 ! Q6P1A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020714 name: ZNF341_human def: "Zinc finger protein 341 gene" [UniProtKB:Q9BYN7] xref: EMBL:AK027550 xref: EMBL:AL050349 xref: EMBL:BC132873 xref: EMBL:BC146811 xref: HGNC:HGNC:15992 xref: UniGene:Hs.516989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058580 ! ZN341_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020715 name: ZNF343_human def: "Zinc finger protein 343 gene" [UniProtKB:Q6P1L6] xref: EMBL:AK055734 xref: EMBL:AK096911 xref: EMBL:AL049650 xref: EMBL:BC002897 xref: EMBL:BC011862 xref: EMBL:BC065009 xref: HGNC:HGNC:16017 xref: UniGene:Hs.516846 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056879 ! ZN343_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020716 name: ZNF345_human def: "Zinc finger protein 345 gene" [UniProtKB:Q14585] xref: EMBL:BC032863 xref: EMBL:X78933 xref: HGNC:HGNC:16367 xref: UniGene:Hs.362324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055997 ! ZN345_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020717 name: ZNF350_human def: "Zinc finger protein 350 gene" [UniProtKB:Q9GZX5] synonym: "ZBRK1" EXACT [UniProtKB:Q9GZX5] xref: EMBL:AF295096 xref: EMBL:AF309561 xref: EMBL:AK023467 xref: EMBL:BC009921 xref: EMBL:CH471135 xref: HGNC:HGNC:16656 xref: UniGene:Hs.407694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058641 ! ZN350_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020718 name: ZNF358_human def: "Zinc finger protein 358 gene" [UniProtKB:Q9NW07] xref: EMBL:AK001252 xref: EMBL:BC003585 xref: EMBL:BC014002 xref: HGNC:HGNC:16838 xref: UniGene:Hs.133475 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058935 ! ZN358_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020719 name: ZNF362_human def: "Zinc finger protein 362 gene" [UniProtKB:Q5T0B9] synonym: "PP6997" EXACT [UniProtKB:Q5T0B9] xref: EMBL:AF318356 xref: EMBL:AL513327 xref: EMBL:BC104779 xref: EMBL:BC112113 xref: EMBL:CH471059 xref: HGNC:HGNC:18079 xref: UniGene:Hs.524248 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056562 ! ZN362_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020720 name: ZNF366_human def: "Zinc finger protein 366 gene" [UniProtKB:Q8N895] xref: EMBL:AK097115 xref: EMBL:BK000210 xref: HGNC:HGNC:18316 xref: UniGene:Hs.370303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057514 ! ZN366_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020721 name: ZNF367_human def: "Zinc finger protein 367 gene" [UniProtKB:Q7RTV3] synonym: "ZFF29" EXACT [UniProtKB:Q7RTV3] xref: EMBL:AL133477 xref: EMBL:AY554164 xref: EMBL:AY554165 xref: EMBL:BC126141 xref: EMBL:BK000211 xref: HGNC:HGNC:18320 xref: UniGene:Hs.494557 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057138 ! ZN367_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020722 name: ZNF37A_human def: "Zinc finger protein 37A gene" [UniProtKB:P17032] synonym: "KOX21" EXACT [UniProtKB:P17032] synonym: "ZNF37" EXACT [UniProtKB:P17032] xref: EMBL:AJ492195 xref: EMBL:AL117339 xref: EMBL:BC015858 xref: EMBL:X52352 xref: EMBL:X69115 xref: HGNC:HGNC:13102 xref: UniGene:Hs.292575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055075 ! ZN37A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020723 name: ZNF382_human def: "Zinc finger protein 382 gene" [UniProtKB:Q96SR6] xref: EMBL:AC092295 xref: EMBL:AF513816 xref: EMBL:AK027592 xref: HGNC:HGNC:17409 xref: UniGene:Hs.631591 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054076 ! A8MW98_HUMAN relationship: codes_for CCO:B0058395 ! ZN382_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020724 name: ZNF383_human def: "Zinc finger protein 383 gene" [UniProtKB:Q8NA42] synonym: "HSD17" EXACT [UniProtKB:Q8NA42] xref: EMBL:AK093182 xref: EMBL:AY260141 xref: EMBL:AY438646 xref: HGNC:HGNC:18609 xref: UniGene:Hs.590975 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057544 ! ZN383_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020725 name: ZNF384_human def: "Zinc finger protein 384 gene" [UniProtKB:Q8TF68] synonym: "CAGH1" EXACT [UniProtKB:Q8TF68] synonym: "CIZ" EXACT [UniProtKB:Q8TF68] synonym: "NMP4" EXACT [UniProtKB:Q8TF68] synonym: "TNRC1" EXACT [UniProtKB:Q8TF68] xref: EMBL:AB070238 xref: EMBL:AK095734 xref: EMBL:U80738 xref: HGNC:HGNC:11955 xref: UniGene:Hs.103315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057966 ! ZN384_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020726 name: ZNF391_human def: "Zinc finger protein 391 gene" [UniProtKB:Q9UJN7] xref: EMBL:AL031118 xref: HGNC:HGNC:18779 xref: UniGene:Hs.651176 xref: UniGene:Hs.680366 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059173 ! ZN391_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020727 name: ZNF394_human def: "Zinc finger protein 394 gene" [UniProtKB:Q53GI3] synonym: "ZKSCAN14" EXACT [UniProtKB:Q53GI3] xref: EMBL:AK022360 xref: EMBL:AK222948 xref: EMBL:AY642122 xref: EMBL:BC017051 xref: EMBL:BC025241 xref: EMBL:BC051847 xref: HGNC:HGNC:18832 xref: UniGene:Hs.386324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055762 ! Q05DA6_HUMAN relationship: codes_for CCO:B0056360 ! ZN394_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020728 name: ZNF395_human def: "Zinc finger protein 395 gene" [UniProtKB:Q9H8N7] synonym: "HDBP2" EXACT [UniProtKB:Q9H8N7] synonym: "PBF" EXACT [UniProtKB:Q9H8N7] xref: EMBL:AB044750 xref: EMBL:AB044751 xref: EMBL:AB044752 xref: EMBL:AB057659 xref: EMBL:AB073627 xref: EMBL:AF263928 xref: EMBL:AK002050 xref: EMBL:AK023418 xref: EMBL:BC001237 xref: HGNC:HGNC:18737 xref: UniGene:Hs.695998 xref: UniGene:Hs.699209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058750 ! ZN395_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020729 name: ZNF396_human def: "Zinc finger protein 396 gene" [UniProtKB:Q96N95] synonym: "ZSCAN14" EXACT [UniProtKB:Q96N95] xref: EMBL:AF492004 xref: EMBL:AF533251 xref: EMBL:AK055775 xref: EMBL:BC036765 xref: HGNC:HGNC:18824 xref: UniGene:Hs.351005 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056910 ! Q6PID1_HUMAN relationship: codes_for CCO:B0058302 ! ZN396_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020730 name: ZNF397_human def: "Zinc finger protein 397 gene" [UniProtKB:Q8NF99] synonym: "ZNF47" EXACT [UniProtKB:Q8NF99] synonym: "ZSCAN15" EXACT [UniProtKB:Q8NF99] xref: EMBL:AF533250 xref: EMBL:AK027384 xref: EMBL:AY157641 xref: EMBL:BC006172 xref: EMBL:CH471088 xref: HGNC:HGNC:18818 xref: UniGene:Hs.591061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057597 ! ZN397_HUMAN relationship: codes_for CCO:B0058253 ! Q96K65_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020731 name: ZNF398_human def: "Zinc finger protein 398 gene" [UniProtKB:Q8TD17] synonym: "KIAA1339" EXACT [UniProtKB:Q8TD17] synonym: "ZER6" EXACT [UniProtKB:Q8TD17] xref: EMBL:AB037760 xref: EMBL:AC004890 xref: EMBL:AY049743 xref: EMBL:AY049744 xref: EMBL:BC043295 xref: HGNC:HGNC:18373 xref: UniGene:Hs.654721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057920 ! ZN398_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020732 name: ZNF404_human def: "Zinc finger protein 404 gene" [UniProtKB:Q494X3] xref: EMBL:AY166785 xref: EMBL:BC101332 xref: EMBL:BC101333 xref: HGNC:HGNC:19417 xref: UniGene:Hs.76561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056290 ! ZN404_HUMAN relationship: codes_for CCO:B0057276 ! Q86WM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020733 name: ZNF407_human def: "Zinc finger protein 407 gene" [UniProtKB:Q9C0G0] synonym: "KIAA1703" EXACT [UniProtKB:Q9C0G0] xref: EMBL:AB051490 xref: EMBL:AC015819 xref: EMBL:AC023380 xref: EMBL:AC091589 xref: EMBL:AC100783 xref: EMBL:AC138660 xref: EMBL:AK000314 xref: EMBL:AK000317 xref: EMBL:AK023901 xref: EMBL:AK056288 xref: HGNC:HGNC:19904 xref: UniGene:Hs.536490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058619 ! ZN407_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020734 name: ZNF408_human def: "Zinc finger protein 408 gene" [UniProtKB:Q9H9D4] synonym: "PFM14" EXACT [UniProtKB:Q9H9D4] synonym: "PRDM17" EXACT [UniProtKB:Q9H9D4] xref: EMBL:AF346626 xref: EMBL:AK022889 xref: EMBL:BC013355 xref: EMBL:BC015708 xref: HGNC:HGNC:20041 xref: UniGene:Hs.656931 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058754 ! ZN408_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020735 name: ZNF409_human def: "Zinc finger protein 409 gene" [UniProtKB:Q9UPU6] synonym: "KIAA1056" EXACT [UniProtKB:Q9UPU6] xref: EMBL:AB028979 xref: HGNC:HGNC:20042 xref: UniGene:Hs.508937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059267 ! ZN409_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020736 name: ZNF410_human def: "Zinc finger protein 410 gene" [UniProtKB:Q86VK4] synonym: "APA1" EXACT [UniProtKB:Q86VK4] xref: EMBL:BC000330 xref: EMBL:BC004357 xref: EMBL:BC050683 xref: EMBL:U90919 xref: HGNC:HGNC:20144 xref: UniGene:Hs.270869 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057261 ! ZN410_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020737 name: ZNF414_human def: "Zinc finger protein 414 gene" [UniProtKB:Q96IQ9] xref: EMBL:BC007310 xref: EMBL:BC071937 xref: HGNC:HGNC:20630 xref: UniGene:Hs.515114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058231 ! ZN414_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020738 name: ZNF415_human def: "Zinc finger protein 415 gene" [UniProtKB:Q09FC8] xref: EMBL:AK002053 xref: EMBL:AY283600 xref: EMBL:BC063880 xref: EMBL:BC069668 xref: EMBL:DQ925695 xref: EMBL:DQ925696 xref: EMBL:DQ925697 xref: EMBL:DQ925698 xref: HGNC:HGNC:20636 xref: UniGene:Hs.147765 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055806 ! ZN415_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020739 name: ZNF416_human def: "Zinc finger protein 416 gene" [UniProtKB:Q9BWM5] xref: EMBL:AC003682 xref: EMBL:AK000564 xref: EMBL:BC000130 xref: HGNC:HGNC:20645 xref: UniGene:Hs.247711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053856 ! A6NI23_HUMAN relationship: codes_for CCO:B0058534 ! ZN416_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020740 name: ZNF417_human def: "Zinc finger protein 417 gene" [UniProtKB:Q8TAU3] xref: EMBL:BC025783 xref: HGNC:HGNC:20646 xref: UniGene:Hs.288995 xref: UniGene:Hs.567710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057893 ! ZN417_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020741 name: ZNF418_human def: "Zinc finger protein 418 gene" [UniProtKB:Q8TF45] synonym: "KIAA1956" EXACT [UniProtKB:Q8TF45] xref: EMBL:AB075836 xref: EMBL:AK056113 xref: EMBL:AY695825 xref: EMBL:BC112244 xref: EMBL:BC113707 xref: HGNC:HGNC:20647 xref: UniGene:Hs.660728 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057963 ! ZN418_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020742 name: ZNF420_human def: "Zinc finger protein 420 gene" [UniProtKB:Q8TAQ5] xref: EMBL:AC010632 xref: EMBL:AK315728 xref: EMBL:BC026210 xref: HGNC:HGNC:20649 xref: UniGene:Hs.444992 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054040 ! A8MUG1_HUMAN relationship: codes_for CCO:B0057891 ! ZN420_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020743 name: ZNF423_human def: "Zinc finger protein 423 gene" [UniProtKB:Q2M1K9] synonym: "KIAA0760" EXACT [UniProtKB:Q2M1K9] synonym: "OAZ" EXACT [UniProtKB:Q2M1K9] xref: EMBL:AB018303 xref: EMBL:AF221712 xref: EMBL:BC112315 xref: EMBL:BC112317 xref: HGNC:HGNC:16762 xref: UniGene:Hs.530930 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056205 ! ZN423_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020744 name: ZNF425_human def: "Zinc finger protein 425 gene" [UniProtKB:Q6IV72] xref: EMBL:AC073422 xref: EMBL:AY621067 xref: HGNC:HGNC:20690 xref: UniGene:Hs.31743 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054055 ! A8MV43_HUMAN relationship: codes_for CCO:B0056830 ! ZN425_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020745 name: ZNF426_human def: "Zinc finger protein 426 gene" [UniProtKB:Q9BUY5] xref: EMBL:BC001791 xref: HGNC:HGNC:20725 xref: UniGene:Hs.594011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058524 ! ZN426_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020746 name: ZNF432_human def: "Zinc finger protein 432 gene" [UniProtKB:O94892] synonym: "KIAA0798" EXACT [UniProtKB:O94892] xref: EMBL:AB018341 xref: EMBL:BC002858 xref: HGNC:HGNC:20810 xref: UniGene:Hs.655934 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054706 ! ZN432_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020747 name: ZNF433_human def: "Zinc finger protein 433 gene" [UniProtKB:Q8N7K0] xref: EMBL:AK098300 xref: EMBL:BC047412 xref: EMBL:CH471106 xref: HGNC:HGNC:20811 xref: UniGene:Hs.667776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057503 ! ZN433_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020748 name: ZNF434_human def: "Zinc finger protein 434 gene" [UniProtKB:Q9NX65] synonym: "HCCS5" EXACT [UniProtKB:Q9NX65] xref: EMBL:AF390550 xref: EMBL:AK000424 xref: EMBL:AK291213 xref: EMBL:AY261676 xref: EMBL:AY279347 xref: EMBL:BC002859 xref: HGNC:HGNC:20812 xref: UniGene:Hs.592078 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056969 ! Q6WMU8_HUMAN relationship: codes_for CCO:B0058950 ! ZN434_HUMAN relationship: codes_for CCO:B0062898 ! Q9BU74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020749 name: ZNF436_human def: "Zinc finger protein 436 gene" [UniProtKB:Q9C0F3] synonym: "KIAA1710" EXACT [UniProtKB:Q9C0F3] xref: EMBL:AB051497 xref: EMBL:AL109936 xref: EMBL:AL834485 xref: EMBL:BC056400 xref: HGNC:HGNC:20814 xref: UniGene:Hs.293798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056612 ! Q5TEG9_HUMAN relationship: codes_for CCO:B0058618 ! ZN436_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020750 name: ZNF438_human def: "Zinc finger protein 438 gene" [UniProtKB:Q7Z4V0] xref: EMBL:AF428258 xref: EMBL:AK131357 xref: EMBL:AL359532 xref: EMBL:AL833056 xref: EMBL:BC101622 xref: EMBL:BC104757 xref: EMBL:DQ356011 xref: EMBL:DQ356012 xref: HGNC:HGNC:21029 xref: UniGene:Hs.660642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057167 ! ZN438_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020751 name: ZNF439_human def: "Zinc finger protein 439 gene" [UniProtKB:Q8NDP4] xref: EMBL:AK027542 xref: EMBL:AL833935 xref: EMBL:BC032857 xref: HGNC:HGNC:20873 xref: UniGene:Hs.528731 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057577 ! ZN439_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020752 name: ZNF440_human def: "Zinc finger protein 440 gene" [UniProtKB:Q8IYI8] xref: EMBL:AK095252 xref: EMBL:BC035760 xref: HGNC:HGNC:20874 xref: UniGene:Hs.418192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057388 ! ZN440_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020753 name: ZNF441_human def: "Zinc finger protein 441 gene" [UniProtKB:Q8N8Z8] xref: EMBL:AK095956 xref: HGNC:HGNC:20875 xref: UniGene:Hs.675132 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057529 ! ZN441_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020754 name: ZNF442_human def: "Zinc finger protein 442 gene" [UniProtKB:Q9H7R0] xref: EMBL:AK024418 xref: HGNC:HGNC:20877 xref: UniGene:Hs.253193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058744 ! ZN442_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020755 name: ZNF444_human def: "Zinc finger protein 444 gene" [UniProtKB:Q8N0Y2] synonym: "EZF2" EXACT [UniProtKB:Q8N0Y2] synonym: "ZSCAN17" EXACT [UniProtKB:Q8N0Y2] xref: EMBL:AB052954 xref: EMBL:AB052955 xref: EMBL:AK001999 xref: EMBL:AK074063 xref: EMBL:AL834130 xref: EMBL:BC021282 xref: HGNC:HGNC:16052 xref: UniGene:Hs.24545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057416 ! ZN444_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020756 name: ZNF445_human def: "Zinc finger protein 445 gene" [UniProtKB:P59923] synonym: "ZKSCAN15" EXACT [UniProtKB:P59923] synonym: "ZNF168" EXACT [UniProtKB:P59923] xref: EMBL:AY262260 xref: EMBL:AY295873 xref: EMBL:BC101486 xref: HGNC:HGNC:21018 xref: UniGene:Hs.250481 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055593 ! ZN445_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020757 name: ZNF449_human def: "Zinc finger protein 449 gene" [UniProtKB:Q6P9G9] synonym: "ZSCAN19" EXACT [UniProtKB:Q6P9G9] xref: EMBL:AK074194 xref: EMBL:AL450472 xref: EMBL:AL833407 xref: EMBL:AY280801 xref: EMBL:BC060768 xref: EMBL:BC065938 xref: HGNC:HGNC:21039 xref: UniGene:Hs.28780 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056474 ! Q5JRZ7_HUMAN relationship: codes_for CCO:B0056897 ! ZN449_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020758 name: ZNF454_human def: "Zinc finger protein 454 gene" [UniProtKB:Q8N9F8] xref: EMBL:AK094763 xref: EMBL:BC105061 xref: HGNC:HGNC:21200 xref: UniGene:Hs.259441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057536 ! ZN454_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020759 name: ZNF460_human def: "Zinc finger protein 460 gene" [UniProtKB:Q14592] synonym: "ZNF272" EXACT [UniProtKB:Q14592] xref: EMBL:AY329492 xref: EMBL:BC109019 xref: EMBL:BC118625 xref: EMBL:X78931 xref: HGNC:HGNC:21628 xref: UniGene:Hs.99971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056003 ! ZN460_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020760 name: ZNF461_human def: "Zinc finger protein 461 gene" [UniProtKB:Q8TAF7] synonym: "GIOT1" EXACT [UniProtKB:Q8TAF7] xref: EMBL:AB021641 xref: EMBL:AY329493 xref: EMBL:BC028631 xref: HGNC:HGNC:21629 xref: UniGene:Hs.590972 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057887 ! ZN461_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020761 name: ZNF462_human def: "Zinc finger protein 462 gene" [UniProtKB:Q96JM2] synonym: "KIAA1803" EXACT [UniProtKB:Q96JM2] xref: EMBL:AB058706 xref: EMBL:BC036884 xref: HGNC:HGNC:21684 xref: UniGene:Hs.370379 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058244 ! ZN462_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020762 name: ZNF467_human def: "Zinc finger protein 467 gene" [UniProtKB:Q7Z7K2] xref: EMBL:BC052625 xref: HGNC:HGNC:23154 xref: UniGene:Hs.112158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057215 ! ZN467_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020763 name: ZNF468_human def: "Zinc finger protein 468 gene" [UniProtKB:Q5VIY5] xref: EMBL:AY442330 xref: EMBL:AY442331 xref: EMBL:CR749381 xref: EMBL:CR936599 xref: HGNC:HGNC:33105 xref: UniGene:Hs.467223 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056642 ! ZN468_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020764 name: ZNF469_human def: "Zinc finger protein 469 gene" [UniProtKB:Q96JG9] synonym: "KIAA1858" EXACT [UniProtKB:Q96JG9] xref: EMBL:AB058761 xref: EMBL:AC135049 xref: HGNC:HGNC:23216 xref: UniGene:Hs.54925 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058239 ! ZN469_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020765 name: ZNF470_human def: "Zinc finger protein 470 gene" [UniProtKB:Q6ECI4] synonym: "CZF1" EXACT [UniProtKB:Q6ECI4] xref: EMBL:AC007228 xref: EMBL:AK129686 xref: EMBL:AY484591 xref: HGNC:HGNC:22220 xref: UniGene:Hs.204449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056731 ! ZN470_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020766 name: ZNF471_human def: "Zinc finger protein 471 gene" [UniProtKB:Q9BX82] synonym: "ERP1" EXACT [UniProtKB:Q9BX82] synonym: "KIAA1396" EXACT [UniProtKB:Q9BX82] xref: EMBL:AB037817 xref: EMBL:AC004696 xref: EMBL:AC005498 xref: EMBL:AF352026 xref: EMBL:AL831845 xref: EMBL:BC125221 xref: HGNC:HGNC:23226 xref: UniGene:Hs.230188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058546 ! ZN471_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020767 name: ZNF473_human def: "Zinc finger protein 473 gene" [UniProtKB:Q8WTR7] synonym: "KIAA1141" EXACT [UniProtKB:Q8WTR7] synonym: "ZFP100" EXACT [UniProtKB:Q8WTR7] xref: EMBL:AB032967 xref: EMBL:AF454744 xref: EMBL:AL080143 xref: EMBL:BC018612 xref: HGNC:HGNC:23239 xref: UniGene:Hs.440553 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057971 ! ZN473_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020768 name: ZNF480_human def: "Zinc finger protein 480 gene" [UniProtKB:Q8WV37] xref: EMBL:AK096442 xref: EMBL:AK096559 xref: EMBL:AL832560 xref: EMBL:AY512662 xref: EMBL:BC007056 xref: EMBL:BC018783 xref: EMBL:BC065503 xref: HGNC:HGNC:23305 xref: UniGene:Hs.147025 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055764 ! Q05DL7_HUMAN relationship: codes_for CCO:B0057989 ! ZN480_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020769 name: ZNF483_human def: "Zinc finger protein 483 gene" [UniProtKB:Q8TF39] synonym: "KIAA1962" EXACT [UniProtKB:Q8TF39] synonym: "ZKSCAN16" EXACT [UniProtKB:Q8TF39] xref: EMBL:AB075842 xref: EMBL:AK092811 xref: EMBL:AK291267 xref: EMBL:AL135787 xref: EMBL:AL159168 xref: EMBL:BC136695 xref: EMBL:BC136696 xref: EMBL:CH471105 xref: HGNC:HGNC:23384 xref: UniGene:Hs.660784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056677 ! Q5VZN3_HUMAN relationship: codes_for CCO:B0057545 ! Q8NAE1_HUMAN relationship: codes_for CCO:B0057962 ! ZN483_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020770 name: ZNF484_human def: "Zinc finger protein 484 gene" [UniProtKB:Q5JVG2] xref: EMBL:AK091203 xref: EMBL:AL136981 xref: EMBL:BC112394 xref: EMBL:BC112396 xref: EMBL:CH471089 xref: HGNC:HGNC:23385 xref: UniGene:Hs.668378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054237 ! B1AL89_HUMAN relationship: codes_for CCO:B0056494 ! ZN484_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020771 name: ZNF485_human def: "Zinc finger protein 485 gene" [UniProtKB:Q8NCK3] xref: EMBL:AK074679 xref: EMBL:AL645634 xref: EMBL:BC014161 xref: HGNC:HGNC:23440 xref: UniGene:Hs.147440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057568 ! ZN485_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020772 name: ZNF486_human def: "Zinc finger protein 486 gene" [UniProtKB:Q96H40] synonym: "KRBO2" EXACT [UniProtKB:Q96H40] xref: EMBL:BC008936 xref: HGNC:HGNC:20807 xref: UniGene:Hs.590991 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058220 ! ZN486_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020773 name: ZNF488_human def: "Zinc finger protein 488 gene" [UniProtKB:Q96MN9] xref: EMBL:AK056666 xref: EMBL:AL731561 xref: EMBL:BC051323 xref: HGNC:HGNC:23535 xref: UniGene:Hs.27788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058291 ! ZN488_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020774 name: ZNF490_human def: "Zinc finger protein 490 gene" [UniProtKB:Q9ULM2] synonym: "KIAA1198" EXACT [UniProtKB:Q9ULM2] xref: EMBL:AB033024 xref: EMBL:BC038586 xref: HGNC:HGNC:23705 xref: UniGene:Hs.655860 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059229 ! ZN490_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020775 name: ZNF491_human def: "Zinc finger protein 491 gene" [UniProtKB:Q8N8L2] xref: EMBL:AK092110 xref: EMBL:AK096593 xref: EMBL:BC101590 xref: EMBL:BC101592 xref: HGNC:HGNC:23706 xref: UniGene:Hs.631634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057523 ! ZN491_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020776 name: ZNF492_human def: "Zinc finger protein 492 gene" [UniProtKB:Q9P255] synonym: "KIAA1473" EXACT [UniProtKB:Q9P255] xref: EMBL:AB040906 xref: EMBL:BC110575 xref: HGNC:HGNC:23707 xref: UniGene:Hs.232108 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059053 ! ZN492_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020777 name: ZNF493_human def: "Zinc finger protein 493 gene" [UniProtKB:Q6ZR52] xref: EMBL:AB209086 xref: EMBL:AK093823 xref: EMBL:AK095616 xref: EMBL:AK127476 xref: EMBL:AK128494 xref: EMBL:BC006408 xref: HGNC:HGNC:23708 xref: UniGene:Hs.656558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057038 ! ZN493_HUMAN relationship: codes_for CCO:B0058487 ! Q9BR99_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020778 name: ZNF496_human def: "Zinc finger protein 496 gene" [UniProtKB:Q96IT1] synonym: "ZKSCAN17" EXACT [UniProtKB:Q96IT1] xref: EMBL:BC007263 xref: EMBL:BC025794 xref: HGNC:HGNC:23713 xref: UniGene:Hs.654803 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057907 ! Q8TBS2_HUMAN relationship: codes_for CCO:B0058233 ! ZN496_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020779 name: ZNF497_human def: "Zinc finger protein 497 gene" [UniProtKB:Q6ZNH5] xref: EMBL:AF064790 xref: EMBL:AK126727 xref: EMBL:AK131209 xref: EMBL:BC125273 xref: HGNC:HGNC:23714 xref: UniGene:Hs.447840 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057026 ! ZN497_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020780 name: ZNF498_human def: "Zinc finger protein 498 gene" [UniProtKB:Q6NSZ9] synonym: "ZSCAN25" EXACT [UniProtKB:Q6NSZ9] xref: EMBL:AK160369 xref: EMBL:BC069644 xref: EMBL:BC074902 xref: EMBL:BC074903 xref: EMBL:BC089402 xref: EMBL:BC114573 xref: EMBL:BC114941 xref: EMBL:BX640720 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: HGNC:HGNC:21961 xref: UniGene:Hs.446297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056855 ! ZN498_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020781 name: ZNF500_human def: "Zinc finger protein 500 gene" [UniProtKB:O60304] synonym: "KIAA0557" EXACT [UniProtKB:O60304] synonym: "ZKSCAN18" EXACT [UniProtKB:O60304] xref: EMBL:AB011129 xref: EMBL:BC004125 xref: EMBL:BC121013 xref: HGNC:HGNC:23716 xref: UniGene:Hs.513316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054543 ! ZN500_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020782 name: ZNF501_human def: "Zinc finger protein 501 gene" [UniProtKB:Q96CX3] synonym: "ZNF52" EXACT [UniProtKB:Q96CX3] xref: EMBL:AK054613 xref: EMBL:BC013762 xref: HGNC:HGNC:23717 xref: UniGene:Hs.401045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058186 ! ZN501_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020783 name: ZNF502_human def: "Zinc finger protein 502 gene" [UniProtKB:Q8TBZ5] xref: EMBL:BC028377 xref: HGNC:HGNC:23718 xref: UniGene:Hs.224843 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057908 ! ZN502_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020784 name: ZNF503_human def: "Zinc finger protein 503 gene" [UniProtKB:Q96F45] xref: EMBL:AK092897 xref: EMBL:BC007494 xref: EMBL:BC011625 xref: EMBL:BC013011 xref: EMBL:BC021165 xref: HGNC:HGNC:23589 xref: UniGene:Hs.195710 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058210 ! ZN503_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020785 name: ZNF506_human def: "Zinc finger protein 506 gene" [UniProtKB:Q5JVG8] xref: EMBL:AL136548 xref: HGNC:HGNC:23780 xref: UniGene:Hs.351906 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056495 ! ZN506_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020786 name: ZNF507_human def: "Zinc finger protein 507 gene" [UniProtKB:Q8TCN5] synonym: "KIAA1084" EXACT [UniProtKB:Q8TCN5] xref: EMBL:AB029007 xref: EMBL:AK292526 xref: EMBL:AL713775 xref: EMBL:BC110332 xref: EMBL:BX640881 xref: HGNC:HGNC:23783 xref: UniGene:Hs.205392 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057915 ! ZN507_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020787 name: ZNF509_human def: "Zinc finger protein 509 gene" [UniProtKB:Q6ZSB9] xref: EMBL:AB209466 xref: EMBL:AK127560 xref: EMBL:BC016477 xref: EMBL:BC089401 xref: HGNC:HGNC:19883 xref: UniGene:Hs.419997 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057052 ! ZN509_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020788 name: ZNF510_human def: "Zinc finger protein 510 gene" [UniProtKB:Q9Y2H8] synonym: "KIAA0972" EXACT [UniProtKB:Q9Y2H8] xref: EMBL:AB023189 xref: EMBL:AL589843 xref: EMBL:BC058022 xref: HGNC:HGNC:29161 xref: UniGene:Hs.75264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056561 ! Q5SZP4_HUMAN relationship: codes_for CCO:B0059306 ! ZN510_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020789 name: ZNF511_human def: "Zinc finger protein 511 gene" [UniProtKB:Q8NB15] xref: EMBL:AK091711 xref: EMBL:AL360181 xref: EMBL:BC015139 xref: EMBL:BC019897 xref: HGNC:HGNC:28445 xref: UniGene:Hs.422113 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057553 ! ZN511_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020790 name: ZNF512_human def: "Zinc finger protein 512 gene" [UniProtKB:Q96ME7] synonym: "KIAA1805" EXACT [UniProtKB:Q96ME7] xref: EMBL:AB058708 xref: EMBL:AK057028 xref: HGNC:HGNC:29380 xref: UniGene:Hs.529178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058287 ! ZN512_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020791 name: ZNF514_human def: "Zinc finger protein 514 gene" [UniProtKB:Q96K75] xref: EMBL:AC092835 xref: EMBL:AK027363 xref: EMBL:AL832263 xref: EMBL:BC074900 xref: EMBL:BC074901 xref: EMBL:BC110524 xref: EMBL:BC110525 xref: HGNC:HGNC:25894 xref: UniGene:Hs.655109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058254 ! ZN514_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020792 name: ZNF516_human def: "Zinc finger protein 516 gene" [UniProtKB:Q92618] synonym: "KIAA0222" EXACT [UniProtKB:Q92618] xref: EMBL:D86975 xref: HGNC:HGNC:28990 xref: UniGene:Hs.436973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058074 ! ZN516_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020793 name: ZNF517_human def: "Zinc finger protein 517 gene" [UniProtKB:Q6ZMY9] xref: EMBL:AK131440 xref: HGNC:HGNC:27984 xref: UniGene:Hs.521942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056998 ! ZN517_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020794 name: ZNF519_human def: "Zinc finger protein 519 gene" [UniProtKB:Q8TB69] xref: EMBL:BC024227 xref: HGNC:HGNC:30574 xref: UniGene:Hs.352635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057899 ! ZN519_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020795 name: ZNF524_human def: "Zinc finger protein 524 gene" [UniProtKB:Q96C55] xref: EMBL:BC007396 xref: EMBL:BC014666 xref: EMBL:BC067748 xref: HGNC:HGNC:28322 xref: UniGene:Hs.440291 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058176 ! ZN524_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020796 name: ZNF525_human def: "Zinc finger protein 525 gene" [UniProtKB:Q8N782] synonym: "KIAA1979" EXACT [UniProtKB:Q8N782] xref: EMBL:AB075859 xref: EMBL:AC010467 xref: EMBL:AK098804 xref: HGNC:HGNC:29423 xref: UniGene:Hs.352638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057499 ! ZN525_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020797 name: ZNF526_human def: "Zinc finger protein 526 gene" [UniProtKB:Q8TF50] synonym: "KIAA1951" EXACT [UniProtKB:Q8TF50] xref: EMBL:AB075831 xref: EMBL:AL833399 xref: EMBL:BC013013 xref: HGNC:HGNC:29415 xref: UniGene:Hs.137282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057965 ! ZN526_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020798 name: ZNF527_human def: "Zinc finger protein 527 gene" [UniProtKB:Q8NB42] synonym: "KIAA1829" EXACT [UniProtKB:Q8NB42] xref: EMBL:AK091585 xref: EMBL:BC014325 xref: HGNC:HGNC:29385 xref: UniGene:Hs.590940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055816 ! Q0P6G1_HUMAN relationship: codes_for CCO:B0057555 ! ZN527_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020799 name: ZNF528_human def: "Zinc finger protein 528 gene" [UniProtKB:Q3MIS6] synonym: "KIAA1827" EXACT [UniProtKB:Q3MIS6] xref: EMBL:AB058730 xref: EMBL:AL832630 xref: EMBL:BC101712 xref: EMBL:BC111950 xref: HGNC:HGNC:29384 xref: UniGene:Hs.662043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017101 ! ZN528_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020800 name: ZNF529_human def: "Zinc finger protein 529 gene" [UniProtKB:Q6P280] synonym: "KIAA1615" EXACT [UniProtKB:Q6P280] xref: EMBL:AB046835 xref: EMBL:AK025110 xref: EMBL:BC064690 xref: HGNC:HGNC:29328 xref: UniGene:Hs.705524 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056882 ! ZN529_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020801 name: ZNF530_human def: "Zinc finger protein 530 gene" [UniProtKB:Q6P9A1] synonym: "KIAA1508" EXACT [UniProtKB:Q6P9A1] xref: EMBL:AB040941 xref: EMBL:AC003682 xref: EMBL:BC060865 xref: HGNC:HGNC:29297 xref: UniGene:Hs.97111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056895 ! ZN530_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020802 name: ZNF532_human def: "Zinc finger protein 532 gene" [UniProtKB:Q9HCE3] synonym: "KIAA1629" EXACT [UniProtKB:Q9HCE3] xref: EMBL:AB046849 xref: EMBL:AK001559 xref: EMBL:AY039256 xref: EMBL:BC036366 xref: EMBL:BC130618 xref: EMBL:BC130620 xref: HGNC:HGNC:30940 xref: UniGene:Hs.529023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058803 ! ZN532_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020803 name: ZNF536_human def: "Zinc finger protein 536 gene" [UniProtKB:O15090] synonym: "KIAA0390" EXACT [UniProtKB:O15090] xref: EMBL:AB002388 xref: HGNC:HGNC:29025 xref: UniGene:Hs.378901 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054405 ! ZN536_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020804 name: ZNF540_human def: "Zinc finger protein 540 gene" [UniProtKB:Q8NDQ6] xref: EMBL:AK131388 xref: EMBL:AL832100 xref: EMBL:AL832315 xref: EMBL:BC017940 xref: EMBL:BC126478 xref: EMBL:BC126480 xref: EMBL:BX537980 xref: HGNC:HGNC:25331 xref: UniGene:Hs.121283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055760 ! Q05D58_HUMAN relationship: codes_for CCO:B0057578 ! ZN540_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020805 name: ZNF542_human def: "Zinc finger protein 542 gene" [UniProtKB:Q5EBM4] xref: EMBL:BC089419 xref: EMBL:BX640680 xref: HGNC:HGNC:25393 xref: UniGene:Hs.467326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056424 ! ZN542_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020806 name: ZNF543_human def: "Zinc finger protein 543 gene" [UniProtKB:Q08ER8] xref: EMBL:AK131547 xref: EMBL:AL834534 xref: EMBL:BC101012 xref: EMBL:BC101013 xref: EMBL:BC101014 xref: EMBL:BC101015 xref: HGNC:HGNC:25281 xref: UniGene:Hs.202544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055803 ! ZN543_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020807 name: ZNF544_human def: "Zinc finger protein 544 gene" [UniProtKB:Q6NX49] xref: EMBL:AF020591 xref: EMBL:AK291656 xref: EMBL:BC042177 xref: EMBL:BC067271 xref: EMBL:CH471135 xref: HGNC:HGNC:16759 xref: UniGene:Hs.438994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053972 ! A8K6J1_HUMAN relationship: codes_for CCO:B0056866 ! ZN544_HUMAN relationship: codes_for CCO:B0057347 ! Q8IVS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020808 name: ZNF546_human def: "Zinc finger protein 546 gene" [UniProtKB:Q86UE3] synonym: "ZNF49" EXACT [UniProtKB:Q86UE3] xref: EMBL:BC045649 xref: HGNC:HGNC:28671 xref: UniGene:Hs.696156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017884 ! ZN546_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020809 name: ZNF547_human def: "Zinc finger protein 547 gene" [UniProtKB:Q8IVP9] xref: EMBL:AK055662 xref: EMBL:BC042681 xref: HGNC:HGNC:26432 xref: UniGene:Hs.446620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057346 ! ZN547_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020810 name: ZNF549_human def: "Zinc finger protein 549 gene" [UniProtKB:Q6P9A3] xref: EMBL:AK092236 xref: EMBL:BC060863 xref: HGNC:HGNC:26632 xref: UniGene:Hs.564295 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056896 ! ZN549_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020811 name: ZNF550_human def: "Zinc finger protein 550 gene" [UniProtKB:Q7Z398] xref: EMBL:AC003682 xref: EMBL:BC034810 xref: EMBL:BC053858 xref: EMBL:BX538032 xref: HGNC:HGNC:28643 xref: UniGene:Hs.180257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057146 ! ZN550_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020812 name: ZNF552_human def: "Zinc finger protein 552 gene" [UniProtKB:Q9H707] xref: EMBL:AC010645 xref: EMBL:AK025256 xref: EMBL:BC046237 xref: EMBL:BC062982 xref: EMBL:BC082767 xref: EMBL:DA345819 xref: HGNC:HGNC:26135 xref: UniGene:Hs.560727 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058737 ! ZN552_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020813 name: ZNF554_human def: "Zinc finger protein 554 gene" [UniProtKB:Q86TJ5] xref: EMBL:AK092136 xref: EMBL:BC000113 xref: EMBL:BC047777 xref: HGNC:HGNC:26629 xref: UniGene:Hs.307043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057240 ! ZN554_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020814 name: ZNF555_human def: "Zinc finger protein 555 gene" [UniProtKB:Q8NEP9] xref: EMBL:AK056659 xref: EMBL:AK093163 xref: EMBL:BC022022 xref: HGNC:HGNC:28382 xref: UniGene:Hs.47712 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057593 ! ZN555_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020815 name: ZNF556_human def: "Zinc finger protein 556 gene" [UniProtKB:Q9HAH1] xref: EMBL:AK021699 xref: EMBL:BC009374 xref: HGNC:HGNC:25669 xref: UniGene:Hs.287433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058761 ! ZN556_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020816 name: ZNF557_human def: "Zinc finger protein 557 gene" [UniProtKB:Q8N988] xref: EMBL:AK095524 xref: EMBL:BC003020 xref: EMBL:BC058040 xref: HGNC:HGNC:28632 xref: UniGene:Hs.591380 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057534 ! ZN557_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020817 name: ZNF558_human def: "Zinc finger protein 558 gene" [UniProtKB:Q96NG5] xref: EMBL:AK055494 xref: EMBL:BC064356 xref: HGNC:HGNC:26422 xref: UniGene:Hs.659797 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058304 ! ZN558_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020818 name: ZNF559_human def: "Zinc finger protein 559 gene" [UniProtKB:Q9BR84] xref: EMBL:BC006436 xref: HGNC:HGNC:28197 xref: UniGene:Hs.655107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058485 ! ZN559_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020819 name: ZNF560_human def: "Zinc finger protein 560 gene" [UniProtKB:Q96MR9] xref: EMBL:AK056548 xref: EMBL:BC101040 xref: EMBL:BC101041 xref: EMBL:BC101042 xref: HGNC:HGNC:26484 xref: UniGene:Hs.631613 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058292 ! ZN560_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020820 name: ZNF561_human def: "Zinc finger protein 561 gene" [UniProtKB:Q8N587] xref: EMBL:BC012144 xref: EMBL:BC032668 xref: HGNC:HGNC:28684 xref: UniGene:Hs.371107 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057471 ! ZN561_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020821 name: ZNF562_human def: "Zinc finger protein 562 gene" [UniProtKB:Q6V9R5] xref: EMBL:AK000086 xref: EMBL:AY346375 xref: HGNC:HGNC:25950 xref: UniGene:Hs.655594 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056959 ! ZN562_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020822 name: ZNF563_human def: "Zinc finger protein 563 gene" [UniProtKB:Q8TA94] xref: EMBL:AK092116 xref: EMBL:BC022523 xref: HGNC:HGNC:30498 xref: UniGene:Hs.663510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057885 ! ZN563_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020823 name: ZNF564_human def: "Zinc finger protein 564 gene" [UniProtKB:Q8TBZ8] xref: EMBL:AK092760 xref: EMBL:BC028367 xref: HGNC:HGNC:31106 xref: UniGene:Hs.655615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057909 ! ZN564_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020824 name: ZNF565_human def: "Zinc finger protein 565 gene" [UniProtKB:Q8N9K5] xref: EMBL:AK094310 xref: EMBL:BC068453 xref: HGNC:HGNC:26726 xref: UniGene:Hs.651111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057538 ! ZN565_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020825 name: ZNF568_human def: "Zinc finger protein 568 gene" [UniProtKB:Q3ZCX4] xref: EMBL:AC008733 xref: EMBL:AK093123 xref: EMBL:BC031218 xref: EMBL:BX640681 xref: HGNC:HGNC:25392 xref: UniGene:Hs.404220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053853 ! A6NHY0_HUMAN relationship: codes_for CCO:B0056286 ! ZN568_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020826 name: ZNF569_human def: "Zinc finger protein 569 gene" [UniProtKB:Q5MCW4] xref: EMBL:AK056615 xref: EMBL:AY835704 xref: EMBL:M88363 xref: HGNC:HGNC:24737 xref: UniGene:Hs.511848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056523 ! ZN569_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020827 name: ZNF570_human def: "Zinc finger protein 570 gene" [UniProtKB:Q96NI8] xref: EMBL:AK055353 xref: HGNC:HGNC:26416 xref: UniGene:Hs.350875 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058306 ! ZN570_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020828 name: ZNF571_human def: "Zinc finger protein 571 gene" [UniProtKB:Q7Z3V5] synonym: "HSPC059" EXACT [UniProtKB:Q7Z3V5] xref: EMBL:AF161544 xref: EMBL:BC040591 xref: EMBL:BC113870 xref: EMBL:BX537401 xref: HGNC:HGNC:25000 xref: UniGene:Hs.590944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057156 ! ZN571_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020829 name: ZNF572_human def: "Zinc finger protein 572 gene" [UniProtKB:Q7Z3I7] xref: EMBL:AK095321 xref: EMBL:BX537876 xref: HGNC:HGNC:26758 xref: UniGene:Hs.175350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057151 ! ZN572_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020830 name: ZNF573_human def: "Zinc finger protein 573 gene" [UniProtKB:Q86YE8] xref: EMBL:AK055483 xref: EMBL:AK074539 xref: EMBL:BC015418 xref: EMBL:BC029468 xref: EMBL:BC042170 xref: EMBL:BC051263 xref: EMBL:BC064962 xref: HGNC:HGNC:26420 xref: UniGene:Hs.531262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056914 ! Q6PIT4_HUMAN relationship: codes_for CCO:B0057303 ! ZN573_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020831 name: ZNF574_human def: "Zinc finger protein 574 gene" [UniProtKB:Q6ZN55] xref: EMBL:AK025712 xref: EMBL:AK074788 xref: EMBL:AK131369 xref: EMBL:AK131418 xref: EMBL:BC001184 xref: EMBL:BC071962 xref: HGNC:HGNC:26166 xref: UniGene:Hs.13323 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057012 ! ZN574_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020832 name: ZNF575_human def: "Zinc finger protein 575 gene" [UniProtKB:Q86XF7] xref: EMBL:BC043611 xref: HGNC:HGNC:27606 xref: UniGene:Hs.213534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057287 ! ZN575_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020833 name: ZNF576_human def: "Zinc finger protein 576 gene" [UniProtKB:Q9H609] xref: EMBL:AK026353 xref: EMBL:BC002981 xref: HGNC:HGNC:28357 xref: UniGene:Hs.11110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058730 ! ZN576_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020834 name: ZNF577_human def: "Zinc finger protein 577 gene" [UniProtKB:Q9BSK1] xref: EMBL:BC004992 xref: HGNC:HGNC:28673 xref: UniGene:Hs.148322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058506 ! ZN577_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020835 name: ZNF578_human def: "Zinc finger protein 578 gene" [UniProtKB:Q96N58] xref: EMBL:AK055946 xref: HGNC:HGNC:26449 xref: UniGene:Hs.157287 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058299 ! ZN578_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020836 name: ZNF579_human def: "Zinc finger protein 579 gene" [UniProtKB:Q8NAF0] xref: EMBL:AK092772 xref: HGNC:HGNC:26646 xref: UniGene:Hs.112529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057546 ! ZN579_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020837 name: ZNF583_human def: "Zinc finger protein 583 gene" [UniProtKB:Q96ND8] xref: EMBL:AF024698 xref: EMBL:AK055592 xref: EMBL:BC111772 xref: HGNC:HGNC:26427 xref: UniGene:Hs.146854 xref: UniGene:Hs.638578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058303 ! ZN583_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020838 name: ZNF584_human def: "Zinc finger protein 584 gene" [UniProtKB:Q8IVC4] xref: EMBL:BC017651 xref: EMBL:BC033149 xref: HGNC:HGNC:27318 xref: UniGene:Hs.439551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057342 ! ZN584_HUMAN relationship: codes_for CCO:B0057998 ! Q8WVQ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020839 name: ZNF586_human def: "Zinc finger protein 586 gene" [UniProtKB:Q9NXT0] xref: EMBL:AC003006 xref: EMBL:AK000077 xref: EMBL:AK302151 xref: EMBL:CH471135 xref: HGNC:HGNC:25949 xref: UniGene:Hs.288995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058956 ! ZN586_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020840 name: ZNF587_human def: "Zinc finger protein 587 gene" [UniProtKB:Q96SQ5] xref: EMBL:AK027616 xref: EMBL:AK160374 xref: EMBL:BC126237 xref: EMBL:BC126239 xref: HGNC:HGNC:30955 xref: UniGene:Hs.288995 xref: UniGene:Hs.642598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058393 ! ZN587_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020841 name: ZNF589_human def: "Zinc finger protein 589 gene" [UniProtKB:Q86UQ0] synonym: "SZF1" EXACT [UniProtKB:Q86UQ0] xref: EMBL:AF114816 xref: EMBL:AF114817 xref: EMBL:AL832831 xref: EMBL:AY258146 xref: EMBL:BC005859 xref: EMBL:BC006247 xref: EMBL:BC048798 xref: EMBL:CH471055 xref: HGNC:HGNC:16747 xref: UniGene:Hs.172602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057251 ! ZN589_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020842 name: ZNF592_human def: "Zinc finger protein 592 gene" [UniProtKB:Q92610] synonym: "KIAA0211" EXACT [UniProtKB:Q92610] xref: EMBL:BC094688 xref: EMBL:BC112232 xref: EMBL:BC112234 xref: EMBL:CH471101 xref: EMBL:D86966 xref: HGNC:HGNC:28986 xref: UniGene:Hs.79347 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058071 ! ZN592_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020843 name: ZNF593_human def: "Zinc finger protein 593 gene" [UniProtKB:O00488] xref: EMBL:BC002580 xref: EMBL:BC019267 xref: EMBL:D45213 xref: HGNC:HGNC:30943 xref: UniGene:Hs.477273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054328 ! ZN593_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020844 name: ZNF594_human def: "Zinc finger protein 594 gene" [UniProtKB:Q96JF6] synonym: "KIAA1871" EXACT [UniProtKB:Q96JF6] xref: EMBL:AB058774 xref: EMBL:AY500358 xref: HGNC:HGNC:29392 xref: UniGene:Hs.658402 xref: UniGene:Hs.699950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058238 ! ZN594_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020845 name: ZNF595_human def: "Zinc finger protein 595 gene" [UniProtKB:Q8IYB9] xref: EMBL:BC036110 xref: EMBL:BC043151 xref: EMBL:BX537887 xref: HGNC:HGNC:27196 xref: UniGene:Hs.428579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057150 ! Q7Z3I0_HUMAN relationship: codes_for CCO:B0057385 ! ZN595_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020846 name: ZNF596_human def: "Zinc finger protein 596 gene" [UniProtKB:Q8TC21] xref: EMBL:AC004908 xref: EMBL:AK093442 xref: EMBL:BC026190 xref: HGNC:HGNC:27268 xref: UniGene:Hs.591388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057911 ! ZN596_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020847 name: ZNF597_human def: "Zinc finger protein 597 gene" [UniProtKB:Q96LX8] xref: EMBL:AK057633 xref: EMBL:BC029899 xref: HGNC:HGNC:26573 xref: UniGene:Hs.88630 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058278 ! ZN597_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020848 name: ZNF599_human def: "Zinc finger protein 599 gene" [UniProtKB:Q96NL3] xref: EMBL:AC020910 xref: EMBL:AK055225 xref: EMBL:BC044615 xref: EMBL:BC092428 xref: HGNC:HGNC:26408 xref: UniGene:Hs.590961 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054092 ! A8MX67_HUMAN relationship: codes_for CCO:B0058309 ! ZN599_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020849 name: ZNF600_human def: "Zinc finger protein 600 gene" [UniProtKB:Q6ZNG1] xref: EMBL:AK131231 xref: EMBL:BX640933 xref: HGNC:HGNC:30951 xref: UniGene:Hs.696848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057023 ! ZN600_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020850 name: ZNF605_human def: "Zinc finger protein 605 gene" [UniProtKB:Q86T29] xref: EMBL:AC127070 xref: EMBL:AL832191 xref: EMBL:AL832623 xref: HGNC:HGNC:28068 xref: UniGene:Hs.29698 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054025 ! A8MTE7_HUMAN relationship: codes_for CCO:B0057237 ! ZN605_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020851 name: ZNF606_human def: "Zinc finger protein 606 gene" [UniProtKB:Q8WXB4] synonym: "KIAA1852" EXACT [UniProtKB:Q8WXB4] synonym: "ZNF328" EXACT [UniProtKB:Q8WXB4] xref: EMBL:AB058755 xref: EMBL:AF455357 xref: EMBL:BC037209 xref: HGNC:HGNC:25879 xref: UniGene:Hs.654967 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058013 ! ZN606_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020852 name: ZNF610_human def: "Zinc finger protein 610 gene" [UniProtKB:Q8N9Z0] xref: EMBL:AK093359 xref: EMBL:AL831871 xref: EMBL:BC039903 xref: EMBL:BC105967 xref: HGNC:HGNC:26687 xref: UniGene:Hs.357663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057541 ! ZN610_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020853 name: ZNF611_human def: "Zinc finger protein 611 gene" [UniProtKB:Q8N823] xref: EMBL:AK097434 xref: EMBL:AL834123 xref: HGNC:HGNC:28766 xref: UniGene:Hs.143951 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057510 ! ZN611_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020854 name: ZNF613_human def: "Zinc finger protein 613 gene" [UniProtKB:Q6PF04] xref: EMBL:AK027565 xref: EMBL:BC057776 xref: HGNC:HGNC:25827 xref: UniGene:Hs.183390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056902 ! ZN613_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020855 name: ZNF614_human def: "Zinc finger protein 614 gene" [UniProtKB:Q8N883] xref: EMBL:AC011468 xref: EMBL:AK097156 xref: EMBL:BC004930 xref: EMBL:BC022246 xref: EMBL:BC101392 xref: EMBL:BC101393 xref: EMBL:BC101394 xref: EMBL:BC101395 xref: EMBL:CH471135 xref: HGNC:HGNC:24722 xref: UniGene:Hs.292336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054029 ! A8MTK7_HUMAN relationship: codes_for CCO:B0057512 ! ZN614_HUMAN relationship: codes_for CCO:B0058508 ! Q9BSN8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020856 name: ZNF615_human def: "Zinc finger protein 615 gene" [UniProtKB:Q8N8J6] xref: EMBL:AK096691 xref: EMBL:AK128361 xref: EMBL:AK131494 xref: EMBL:BC105100 xref: EMBL:BC105102 xref: EMBL:CR936612 xref: HGNC:HGNC:24740 xref: UniGene:Hs.368355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057522 ! ZN615_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020857 name: ZNF616_human def: "Zinc finger protein 616 gene" [UniProtKB:Q08AN1] xref: EMBL:AL832969 xref: EMBL:BC033199 xref: EMBL:BC125099 xref: HGNC:HGNC:28062 xref: UniGene:Hs.645225 xref: UniGene:Hs.656670 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017883 ! ZN616_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020858 name: ZNF618_human def: "Zinc finger protein 618 gene" [UniProtKB:Q5T7W0] synonym: "KIAA1952" EXACT [UniProtKB:Q5T7W0] xref: EMBL:AB075832 xref: EMBL:AK126896 xref: EMBL:AL137850 xref: EMBL:AL162393 xref: EMBL:BC012922 xref: EMBL:BC036039 xref: EMBL:BC053892 xref: HGNC:HGNC:29416 xref: UniGene:Hs.349208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056595 ! ZN618_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020859 name: ZNF619_human def: "Zinc finger protein 619 gene" [UniProtKB:Q8N2I2] xref: EMBL:AK075245 xref: HGNC:HGNC:26910 xref: UniGene:Hs.407159 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057444 ! ZN619_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020860 name: ZNF620_human def: "Zinc finger protein 620 gene" [UniProtKB:Q6ZNG0] xref: EMBL:AK093599 xref: EMBL:AK131232 xref: HGNC:HGNC:28742 xref: UniGene:Hs.581541 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057022 ! ZN620_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020861 name: ZNF621_human def: "Zinc finger protein 621 gene" [UniProtKB:Q6ZSS3] xref: EMBL:AK074366 xref: EMBL:AK127181 xref: EMBL:BC101619 xref: EMBL:BC113415 xref: EMBL:CR749268 xref: HGNC:HGNC:24787 xref: UniGene:Hs.19977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057058 ! ZN621_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020862 name: ZNF623_human def: "Zinc finger protein 623 gene" [UniProtKB:O75123] synonym: "KIAA0628" EXACT [UniProtKB:O75123] xref: EMBL:AB014528 xref: EMBL:BC067516 xref: EMBL:BC067517 xref: EMBL:BC067518 xref: EMBL:BC075056 xref: EMBL:BC075057 xref: HGNC:HGNC:29084 xref: UniGene:Hs.43133 xref: UniGene:Hs.694018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054603 ! ZN623_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020863 name: ZNF625_human def: "Zinc finger protein 625 gene" [UniProtKB:Q96I27] xref: EMBL:BC007868 xref: HGNC:HGNC:30571 xref: UniGene:Hs.512823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058225 ! ZN625_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020864 name: ZNF627_human def: "Zinc finger protein 627 gene" [UniProtKB:Q7L945] xref: EMBL:AF024694 xref: EMBL:AK074846 xref: EMBL:BC006279 xref: EMBL:BC069232 xref: EMBL:BC098416 xref: HGNC:HGNC:30570 xref: UniGene:Hs.526665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057121 ! ZN627_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020865 name: ZNF628_human def: "Zinc finger protein 628 gene" [UniProtKB:Q5EBL2] xref: EMBL:BC047332 xref: EMBL:BC089449 xref: HGNC:HGNC:28054 xref: UniGene:Hs.525209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056423 ! ZN628_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020866 name: ZNF629_human def: "Zinc finger protein 629 gene" [UniProtKB:Q9UEG4] synonym: "KIAA0326" EXACT [UniProtKB:Q9UEG4] synonym: "ZNF65" EXACT [UniProtKB:Q9UEG4] xref: EMBL:AB002324 xref: EMBL:M88374 xref: HGNC:HGNC:29008 xref: UniGene:Hs.301094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059109 ! ZN629_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020867 name: ZNF630_human def: "Zinc finger protein 630 gene" [UniProtKB:Q2M218] xref: EMBL:BC112139 xref: EMBL:CH471164 xref: EMBL:Z98304 xref: HGNC:HGNC:28855 xref: UniGene:Hs.592252 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056208 ! ZN630_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020868 name: ZNF639_human def: "Zinc finger protein 639 gene" [UniProtKB:Q9UID6] synonym: "ZASC1" EXACT [UniProtKB:Q9UID6] xref: EMBL:AB097862 xref: EMBL:AF003924 xref: EMBL:BC020500 xref: EMBL:BC026181 xref: HGNC:HGNC:30950 xref: UniGene:Hs.632578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059156 ! ZN639_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020869 name: ZNF641_human def: "Zinc finger protein 641 gene" [UniProtKB:Q96N77] xref: EMBL:AK055857 xref: EMBL:AL713659 xref: EMBL:AY842285 xref: EMBL:BC018090 xref: HGNC:HGNC:31834 xref: UniGene:Hs.23492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058301 ! ZN641_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020870 name: ZNF642_human def: "Zinc finger protein 642 gene" [UniProtKB:Q49AA0] xref: EMBL:AK122618 xref: EMBL:AL603839 xref: EMBL:BC041873 xref: HGNC:HGNC:24708 xref: UniGene:Hs.434385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056302 ! ZN642_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020871 name: ZNF643_human def: "Zinc finger protein 643 gene" [UniProtKB:Q9UJL9] xref: EMBL:AL031985 xref: EMBL:AL137241 xref: EMBL:BC017498 xref: HGNC:HGNC:28053 xref: UniGene:Hs.133034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056528 ! Q5QPL4_HUMAN relationship: codes_for CCO:B0059172 ! ZN643_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020872 name: ZNF644_human def: "Zinc finger protein 644 gene" [UniProtKB:Q9H582] synonym: "KIAA1221" EXACT [UniProtKB:Q9H582] synonym: "ZEP2" EXACT [UniProtKB:Q9H582] xref: EMBL:AB019255 xref: EMBL:AB033047 xref: EMBL:AL136109 xref: EMBL:BC050656 xref: EMBL:BC063683 xref: HGNC:HGNC:29222 xref: UniGene:Hs.173001 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058723 ! ZN644_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020873 name: ZNF648_human def: "Zinc finger protein 648 gene" [UniProtKB:Q5T619] xref: EMBL:AL355482 xref: HGNC:HGNC:18190 xref: UniGene:Hs.684328 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056587 ! ZN648_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020874 name: ZNF649_human def: "Zinc finger protein 649 gene" [UniProtKB:Q9BS31] xref: EMBL:AC011460 xref: EMBL:AK022706 xref: EMBL:AK315487 xref: EMBL:AL713677 xref: EMBL:BC005368 xref: EMBL:CH471135 xref: HGNC:HGNC:25741 xref: UniGene:Hs.567573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058503 ! ZN649_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020875 name: ZNF652_human def: "Zinc finger protein 652 gene" [UniProtKB:Q9Y2D9] synonym: "KIAA0924" EXACT [UniProtKB:Q9Y2D9] xref: EMBL:AB023141 xref: EMBL:CR933680 xref: HGNC:HGNC:29147 xref: UniGene:Hs.463375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059300 ! ZN652_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020876 name: ZNF653_human def: "Zinc finger protein 653 gene" [UniProtKB:Q96CK0] synonym: "ZIP67" EXACT [UniProtKB:Q96CK0] xref: EMBL:AY072704 xref: EMBL:BC014187 xref: EMBL:BC016816 xref: HGNC:HGNC:25196 xref: UniGene:Hs.465928 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058184 ! ZN653_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020877 name: ZNF654_human def: "Zinc finger protein 654 gene" [UniProtKB:Q8IZM8] xref: EMBL:AF543494 xref: EMBL:AK001859 xref: EMBL:AK024795 xref: HGNC:HGNC:25612 xref: UniGene:Hs.591650 xref: UniGene:Hs.661116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057410 ! ZN654_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020878 name: ZNF658_human def: "Zinc finger protein 658 gene" [UniProtKB:Q5TYW1] xref: EMBL:AK022636 xref: EMBL:AK057375 xref: EMBL:AL110217 xref: EMBL:AL353770 xref: EMBL:BC031626 xref: EMBL:BX664608 xref: HGNC:HGNC:25226 xref: UniGene:Hs.522147 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056636 ! ZN658_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020879 name: ZNF660_human def: "Zinc finger protein 660 gene" [UniProtKB:Q6AZW8] xref: EMBL:AK094189 xref: EMBL:BC075094 xref: EMBL:BC075095 xref: EMBL:BX538171 xref: HGNC:HGNC:26720 xref: UniGene:Hs.669324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056719 ! ZN660_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020880 name: ZNF662_human def: "Zinc finger protein 662 gene" [UniProtKB:Q6ZS27] xref: EMBL:AK127779 xref: EMBL:AK128676 xref: EMBL:AK131235 xref: EMBL:BC128085 xref: HGNC:HGNC:31930 xref: UniGene:Hs.656856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053707 ! A1A4T9_HUMAN relationship: codes_for CCO:B0057045 ! ZN662_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020881 name: ZNF663_human def: "Zinc finger protein 663 gene" [UniProtKB:Q8NDT4] xref: EMBL:AL831934 xref: HGNC:HGNC:25342 xref: UniGene:Hs.377046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057580 ! ZN663_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020882 name: ZNF664_human def: "Zinc finger protein 664 gene" [UniProtKB:Q8N3J9] synonym: "ZFOC1" EXACT [UniProtKB:Q8N3J9] xref: EMBL:AL834266 xref: EMBL:BC051696 xref: EMBL:BC093848 xref: EMBL:BC101530 xref: EMBL:BX647762 xref: EMBL:L41669 xref: HGNC:HGNC:25406 xref: UniGene:Hs.524828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057456 ! ZN664_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020883 name: ZNF665_human def: "Zinc finger protein 665 gene" [UniProtKB:Q9H7R5] synonym: "ZFP160L" EXACT [UniProtKB:Q9H7R5] xref: EMBL:AK024407 xref: EMBL:AK291403 xref: HGNC:HGNC:25885 xref: UniGene:Hs.590980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058745 ! ZN665_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020884 name: ZNF668_human def: "Zinc finger protein 668 gene" [UniProtKB:Q96K58] xref: EMBL:AB209710 xref: EMBL:AK023541 xref: EMBL:AK027398 xref: EMBL:BC021997 xref: HGNC:HGNC:25821 xref: UniGene:Hs.102928 xref: UniGene:Hs.701194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058251 ! ZN668_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020885 name: ZNF669_human def: "Zinc finger protein 669 gene" [UniProtKB:Q96BR6] xref: EMBL:AK022668 xref: EMBL:AL627095 xref: EMBL:BC015312 xref: HGNC:HGNC:25736 xref: UniGene:Hs.163754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056647 ! Q5VT36_HUMAN relationship: codes_for CCO:B0056648 ! Q5VT37_HUMAN relationship: codes_for CCO:B0058170 ! ZN669_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020886 name: ZNF670_human def: "Zinc finger protein 670 gene" [UniProtKB:Q9BS34] xref: EMBL:AK074774 xref: EMBL:AL512637 xref: EMBL:AL627095 xref: EMBL:BC005360 xref: HGNC:HGNC:28167 xref: UniGene:Hs.669893 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058504 ! ZN670_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020887 name: ZNF671_human def: "Zinc finger protein 671 gene" [UniProtKB:Q8TAW3] xref: EMBL:AC003006 xref: EMBL:AK027159 xref: EMBL:BC025728 xref: EMBL:CH471135 xref: HGNC:HGNC:26279 xref: UniGene:Hs.180402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053812 ! A6NF07_HUMAN relationship: codes_for CCO:B0057895 ! ZN671_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020888 name: ZNF672_human def: "Zinc finger protein 672 gene" [UniProtKB:Q499Z4] xref: EMBL:AK025954 xref: EMBL:AK027679 xref: EMBL:BC007385 xref: EMBL:BC008872 xref: EMBL:BC035140 xref: EMBL:BC050348 xref: EMBL:BC068506 xref: HGNC:HGNC:26179 xref: UniGene:Hs.521151 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056296 ! ZN672_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020889 name: ZNF673_human def: "Protein ZNF673 gene" [UniProtKB:Q5JUW0] xref: EMBL:AK000351 xref: EMBL:AL139811 xref: EMBL:BC012569 xref: HGNC:HGNC:26007 xref: UniGene:Hs.632800 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056490 ! ZN673_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020890 name: ZNF674_human def: "Zinc finger protein 674 gene" [UniProtKB:Q2M3X9] xref: EMBL:AY971607 xref: HGNC:HGNC:17625 xref: UniGene:Hs.675818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056214 ! ZN674_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020891 name: ZNF676_human def: "Zinc finger protein 676 gene" [UniProtKB:Q8N7Q3] xref: EMBL:AC073539 xref: EMBL:AK097798 xref: HGNC:HGNC:20429 xref: UniGene:Hs.55452 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057505 ! ZN676_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020892 name: ZNF677_human def: "Zinc finger protein 677 gene" [UniProtKB:Q86XU0] xref: EMBL:BC029855 xref: EMBL:BC050038 xref: HGNC:HGNC:28730 xref: UniGene:Hs.20506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055755 ! Q05C29_HUMAN relationship: codes_for CCO:B0057295 ! ZN677_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020893 name: ZNF678_human def: "Zinc finger protein 678 gene" [UniProtKB:Q5SXM1] xref: EMBL:AL451054 xref: EMBL:AL592310 xref: EMBL:BC042500 xref: HGNC:HGNC:28652 xref: UniGene:Hs.656372 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054273 ! B1APK8_HUMAN relationship: codes_for CCO:B0056549 ! ZN678_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020894 name: ZNF679_human def: "Zinc finger protein 679 gene" [UniProtKB:Q8IYX0] xref: EMBL:BC033523 xref: HGNC:HGNC:28650 xref: UniGene:Hs.520884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057393 ! ZN679_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020895 name: ZNF681_human def: "Zinc finger protein 681 gene" [UniProtKB:Q96N22] xref: EMBL:AK056088 xref: EMBL:BC062216 xref: HGNC:HGNC:26457 xref: UniGene:Hs.187337 xref: UniGene:Hs.399952 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058298 ! ZN681_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020896 name: ZNF683_human def: "Zinc finger protein 683 gene" [UniProtKB:Q8IZ20] xref: EMBL:AL451139 xref: EMBL:BC028731 xref: EMBL:BC029505 xref: HGNC:HGNC:28495 xref: UniGene:Hs.353208 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057395 ! ZN683_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020897 name: ZNF684_human def: "Zinc finger protein 684 gene" [UniProtKB:Q5T5D7] xref: EMBL:AL356379 xref: EMBL:BC091518 xref: EMBL:BC111463 xref: HGNC:HGNC:28418 xref: UniGene:Hs.524767 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056580 ! ZN684_HUMAN relationship: codes_for CCO:B0056581 ! Q5T5D8_HUMAN relationship: codes_for CCO:B0056582 ! Q5T5D9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020898 name: ZNF687_human def: "Zinc finger protein 687 gene" [UniProtKB:Q8N1G0] synonym: "KIAA1441" EXACT [UniProtKB:Q8N1G0] xref: EMBL:AB037862 xref: EMBL:AK023105 xref: EMBL:AL391069 xref: EMBL:BC032463 xref: EMBL:CR749307 xref: HGNC:HGNC:29277 xref: UniGene:Hs.186756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057427 ! ZN687_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020899 name: ZNF688_human def: "Zinc finger protein 688 gene" [UniProtKB:P0C7X2] xref: EMBL:AC002310 xref: EMBL:BC018997 xref: HGNC:HGNC:30489 xref: UniGene:Hs.301463 xref: UniGene:Hs.513509 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057987 ! ZN688_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020900 name: ZNF689_human def: "Zinc finger protein 689 gene" [UniProtKB:Q96CS4] xref: EMBL:AK074896 xref: EMBL:AL834299 xref: EMBL:BC014000 xref: HGNC:HGNC:25173 xref: UniGene:Hs.454685 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058185 ! ZN689_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020901 name: ZNF692_human def: "Zinc finger protein 692 gene" [UniProtKB:Q9BU19] xref: EMBL:AF256175 xref: EMBL:AK000538 xref: EMBL:AK001070 xref: EMBL:AL133100 xref: EMBL:AL672291 xref: EMBL:BC002948 xref: HGNC:HGNC:26049 xref: UniGene:Hs.377705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058516 ! ZN692_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020902 name: ZNF695_human def: "Zinc finger protein 695 gene" [UniProtKB:Q8IW36] xref: EMBL:AC113174 xref: EMBL:AL512637 xref: EMBL:BC023527 xref: EMBL:BC041082 xref: EMBL:BC055096 xref: HGNC:HGNC:30954 xref: UniGene:Hs.669893 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057353 ! ZN695_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020903 name: ZNF696_human def: "Zinc finger protein 696 gene" [UniProtKB:Q9H7X3] xref: EMBL:AK024191 xref: EMBL:BC126317 xref: EMBL:CH471162 xref: HGNC:HGNC:25872 xref: UniGene:Hs.657615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058747 ! ZN696_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020904 name: ZNF697_human def: "Zinc finger protein 697 gene" [UniProtKB:Q5TEC3] xref: EMBL:AL109966 xref: EMBL:BC007260 xref: HGNC:HGNC:32034 xref: UniGene:Hs.381105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056611 ! ZN697_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020905 name: ZNF699_human def: "Zinc finger protein 699 gene" [UniProtKB:Q32M78] xref: EMBL:AK095463 xref: EMBL:BC109267 xref: EMBL:BC109268 xref: HGNC:HGNC:24750 xref: UniGene:Hs.633842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056237 ! ZN699_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020906 name: ZNF700_human def: "Zinc finger protein 700 gene" [UniProtKB:Q9H0M5] xref: EMBL:AL136732 xref: HGNC:HGNC:25292 xref: UniGene:Hs.528486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058654 ! ZN700_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020907 name: ZNF701_human def: "Zinc finger protein 701 gene" [UniProtKB:Q9NV72] xref: EMBL:AC022150 xref: EMBL:AK001753 xref: EMBL:BC080612 xref: HGNC:HGNC:25597 xref: UniGene:Hs.235167 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054057 ! A8MVA1_HUMAN relationship: codes_for CCO:B0054089 ! A8MX31_HUMAN relationship: codes_for CCO:B0058929 ! ZN701_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020908 name: ZNF702_human def: "Zinc finger protein 702 gene" [UniProtKB:Q9H963] xref: EMBL:AC010328 xref: EMBL:AK023047 xref: EMBL:AK092593 xref: EMBL:BC032590 xref: HGNC:HGNC:25775 xref: UniGene:Hs.270435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058753 ! ZN702_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020909 name: ZNF703_human def: "Zinc finger protein 703 gene" [UniProtKB:Q9H7S9] xref: EMBL:AK024361 xref: EMBL:BC032534 xref: EMBL:BC084581 xref: HGNC:HGNC:25883 xref: UniGene:Hs.288042 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058746 ! ZN703_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020910 name: ZNF707_human def: "Zinc finger protein 707 gene" [UniProtKB:Q96C28] xref: EMBL:BC014894 xref: HGNC:HGNC:27815 xref: UniGene:Hs.521922 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058175 ! ZN707_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020911 name: ZNF708_human def: "Zinc finger protein 708 gene" [UniProtKB:P17019] synonym: "KOX8" EXACT [UniProtKB:P17019] synonym: "ZNF15" EXACT [UniProtKB:P17019] synonym: "ZNF15L1" EXACT [UniProtKB:P17019] xref: EMBL:AK131527 xref: EMBL:X52339 xref: HGNC:HGNC:12945 xref: UniGene:Hs.466296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055065 ! ZN708_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020912 name: ZNF709_human def: "Zinc finger protein 709 gene" [UniProtKB:Q8N972] xref: EMBL:AK095600 xref: HGNC:HGNC:20629 xref: UniGene:Hs.676635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057533 ! ZN709_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020913 name: ZNF710_human def: "Zinc finger protein 710 gene" [UniProtKB:Q8N1W2] xref: EMBL:AK094712 xref: EMBL:AK160373 xref: EMBL:AL831826 xref: EMBL:BC126476 xref: EMBL:BC130541 xref: HGNC:HGNC:25352 xref: UniGene:Hs.459311 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057434 ! ZN710_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020914 name: ZNF711_human def: "Zinc finger protein 711 gene" [UniProtKB:Q9Y462] synonym: "CMPX1" EXACT [UniProtKB:Q9Y462] synonym: "ZNF6" EXACT [UniProtKB:Q9Y462] xref: EMBL:BC067294 xref: EMBL:X56465 xref: EMBL:Z82216 xref: HGNC:HGNC:13128 xref: UniGene:Hs.326801 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059348 ! ZN711_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020915 name: ZNF713_human def: "Zinc finger protein 713 gene" [UniProtKB:Q8N859] xref: EMBL:AC092647 xref: EMBL:AK097282 xref: HGNC:HGNC:22043 xref: UniGene:Hs.660834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054071 ! A8MW10_HUMAN relationship: codes_for CCO:B0057511 ! ZN713_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020916 name: ZNF717_human def: "Zinc finger protein 717 gene" [UniProtKB:Q9BY31] xref: EMBL:AC108724 xref: EMBL:AC133123 xref: EMBL:AF226994 xref: EMBL:BC084565 xref: HGNC:HGNC:29448 xref: UniGene:Hs.556877 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056682 ! Q5XG89_HUMAN relationship: codes_for CCO:B0058568 ! ZN717_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020917 name: ZNF718_human def: "Zinc finger protein 718 gene" [UniProtKB:Q3SXZ3] xref: EMBL:BC052600 xref: EMBL:BC104026 xref: EMBL:BC104027 xref: EMBL:BC104028 xref: EMBL:BC104029 xref: HGNC:HGNC:26889 xref: UniGene:Hs.428579 xref: UniGene:Hs.636638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032358 ! Q7Z7K8_HUMAN relationship: codes_for CCO:B0056269 ! ZN718_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020918 name: ZNF720_human def: "Putative protein ZNF720 gene" [UniProtKB:Q7Z2F6] xref: EMBL:AK128671 xref: EMBL:BC018134 xref: EMBL:BC055408 xref: EMBL:CH471192 xref: HGNC:HGNC:26987 xref: UniGene:Hs.660487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057141 ! ZN720_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020919 name: ZNF721_human def: "Zinc finger protein 721 gene" [UniProtKB:Q8TF20] synonym: "KIAA1982" EXACT [UniProtKB:Q8TF20] xref: EMBL:AB075862 xref: EMBL:AL834155 xref: HGNC:HGNC:29425 xref: UniGene:Hs.428360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057960 ! ZN721_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020920 name: ZNF725_human def: "Putative zinc finger protein 725 gene" [UniProtKB:A8MSQ6] xref: EMBL:AC011493 xref: EMBL:AC074140 xref: HGNC:HGNC:32461 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054011 ! ZN725_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020921 name: ZNF738_human def: "Protein ZNF738 gene" [UniProtKB:Q8NE65] xref: EMBL:AC022432 xref: EMBL:AK291002 xref: EMBL:AK291193 xref: EMBL:BC034499 xref: HGNC:HGNC:32469 xref: UniGene:Hs.359535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032363 ! ZN738_HUMAN relationship: codes_for CCO:B0032365 ! A6NEM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020922 name: ZNF740_human def: "Zinc finger protein 740 gene" [UniProtKB:Q8NDX6] synonym: "TB7" EXACT [UniProtKB:Q8NDX6] xref: EMBL:AJ316575 xref: EMBL:BC053557 xref: HGNC:HGNC:27465 xref: UniGene:Hs.524458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057585 ! ZN740_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020923 name: ZNF747_human def: "KRAB domain-containing protein ZNF747 gene" [UniProtKB:Q9BV97] xref: EMBL:AB209546 xref: EMBL:AK054567 xref: EMBL:BC001361 xref: HGNC:HGNC:28350 xref: UniGene:Hs.592032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058526 ! ZN747_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020924 name: ZNF749_human def: "Zinc finger protein 749 gene" [UniProtKB:O43361] xref: EMBL:AC004076 xref: HGNC:HGNC:32783 xref: UniGene:Hs.579576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054474 ! ZN749_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020925 name: ZNF761_human def: "Zinc finger protein 761 gene" [UniProtKB:Q86XN6] synonym: "KIAA2033" EXACT [UniProtKB:Q86XN6] xref: EMBL:AB107355 xref: EMBL:AC022137 xref: EMBL:AK131281 xref: HGNC:HGNC:23179 xref: UniGene:Hs.705729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057291 ! ZN761_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020926 name: ZNF763_human def: "Zinc finger protein 763 gene" [UniProtKB:Q0D2J5] xref: EMBL:BC105711 xref: EMBL:BC105712 xref: EMBL:BC105713 xref: HGNC:HGNC:27614 xref: UniGene:Hs.646386 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055808 ! ZN763_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020927 name: ZNF766_human def: "Zinc finger protein 766 gene" [UniProtKB:Q5HY98] xref: EMBL:BX538183 xref: EMBL:BX648899 xref: HGNC:HGNC:28063 xref: UniGene:Hs.439662 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056442 ! ZN766_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020928 name: ZNF768_human def: "Zinc finger protein 768 gene" [UniProtKB:Q9H5H4] xref: EMBL:AK027089 xref: EMBL:BC013760 xref: EMBL:BC092403 xref: HGNC:HGNC:26273 xref: UniGene:Hs.85658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058725 ! ZN768_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020929 name: ZNF770_human def: "Zinc finger protein 770 gene" [UniProtKB:Q6IQ21] xref: EMBL:AK000589 xref: EMBL:AK131433 xref: EMBL:BC071603 xref: HGNC:HGNC:26061 xref: UniGene:Hs.5327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056825 ! ZN770_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020930 name: ZNF771_human def: "Zinc finger protein 771 gene" [UniProtKB:Q7L3S4] xref: EMBL:AF242768 xref: EMBL:BC011870 xref: EMBL:BC026192 xref: HGNC:HGNC:29653 xref: UniGene:Hs.148584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057118 ! ZN771_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020931 name: ZNF774_human def: "Zinc finger protein 774 gene" [UniProtKB:Q6NX45] xref: EMBL:BC067279 xref: HGNC:HGNC:33108 xref: UniGene:Hs.55307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056865 ! ZN774_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020932 name: ZNF775_human def: "Zinc finger protein 775 gene" [UniProtKB:Q96BV0] xref: EMBL:BC015152 xref: HGNC:HGNC:28501 xref: UniGene:Hs.655734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058171 ! ZN775_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020933 name: ZNF777_human def: "Zinc finger protein 777 gene" [UniProtKB:Q9ULD5] synonym: "KIAA1285" EXACT [UniProtKB:Q9ULD5] xref: EMBL:AB033111 xref: EMBL:AK074515 xref: EMBL:BC023985 xref: HGNC:HGNC:22213 xref: UniGene:Hs.38512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059222 ! ZN777_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020934 name: ZNF778_human def: "Zinc finger protein 778 gene" [UniProtKB:Q96MU6] xref: EMBL:AK056437 xref: EMBL:BC125192 xref: HGNC:HGNC:26479 xref: UniGene:Hs.647385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058293 ! ZN778_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020935 name: ZNF781_human def: "Zinc finger protein 781 gene" [UniProtKB:Q8N8C0] xref: EMBL:AK097019 xref: EMBL:BC108687 xref: HGNC:HGNC:26745 xref: UniGene:Hs.631565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057516 ! ZN781_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020936 name: ZNF782_human def: "Zinc finger protein 782 gene" [UniProtKB:Q6ZMW2] xref: EMBL:AK131468 xref: HGNC:HGNC:33110 xref: UniGene:Hs.592420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056997 ! ZN782_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020937 name: ZNF783_human def: "Protein ZNF783 gene" [UniProtKB:Q6ZMS7] xref: EMBL:AK131504 xref: HGNC:HGNC:27222 xref: UniGene:Hs.490512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056991 ! ZN783_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020938 name: ZNF784_human def: "Zinc finger protein 784 gene" [UniProtKB:Q8NCA9] xref: EMBL:AK074859 xref: EMBL:BC065822 xref: HGNC:HGNC:33111 xref: UniGene:Hs.53996 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057564 ! ZN784_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020939 name: ZNF786_human def: "Zinc finger protein 786 gene" [UniProtKB:Q8N393] xref: EMBL:AL834510 xref: EMBL:BC128392 xref: HGNC:HGNC:21806 xref: UniGene:Hs.632029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057454 ! ZN786_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020940 name: ZNF787_human def: "Zinc finger protein 787 gene" [UniProtKB:Q6DD87] xref: EMBL:AF000560 xref: EMBL:BC077728 xref: HGNC:HGNC:26998 xref: UniGene:Hs.397153 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056723 ! ZN787_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020941 name: ZNF788_human def: "Zinc finger protein 788 gene" [UniProtKB:Q6ZQV5] xref: EMBL:AK128282 xref: EMBL:AK128700 xref: HGNC:HGNC:33112 xref: UniGene:Hs.127473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057035 ! ZN788_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020942 name: ZNF789_human def: "Zinc finger protein 789 gene" [UniProtKB:Q5FWF6] xref: EMBL:AC073063 xref: EMBL:AK131429 xref: EMBL:BC089424 xref: EMBL:CH236956 xref: HGNC:HGNC:27801 xref: UniGene:Hs.440384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053841 ! A6NH61_HUMAN relationship: codes_for CCO:B0056427 ! ZN789_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020943 name: ZNF790_human def: "Zinc finger protein 790 gene" [UniProtKB:Q6PG37] xref: EMBL:BC057245 xref: HGNC:HGNC:33114 xref: UniGene:Hs.282067 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056904 ! ZN790_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020944 name: ZNF791_human def: "Zinc finger protein 791 gene" [UniProtKB:Q3KP31] xref: EMBL:AC010422 xref: EMBL:AK074877 xref: EMBL:BC106937 xref: EMBL:BC106938 xref: EMBL:CH471106 xref: HGNC:HGNC:26895 xref: UniGene:Hs.522545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054107 ! A8MXY6_HUMAN relationship: codes_for CCO:B0056253 ! ZN791_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020945 name: ZNF792_human def: "Zinc finger protein 792 gene" [UniProtKB:Q3KQV3] xref: EMBL:AC008555 xref: EMBL:AK304550 xref: EMBL:BC101118 xref: EMBL:BC101119 xref: EMBL:BC101120 xref: EMBL:BC106043 xref: HGNC:HGNC:24751 xref: UniGene:Hs.50405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056254 ! ZN792_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020946 name: ZNF793_human def: "Zinc finger protein 793 gene" [UniProtKB:Q6ZN11] xref: EMBL:AK131417 xref: EMBL:BX537524 xref: HGNC:HGNC:33115 xref: UniGene:Hs.568010 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057003 ! ZN793_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020947 name: ZNF799_human def: "Zinc finger protein 799 gene" [UniProtKB:Q96GE5] synonym: "ZNF842" EXACT [UniProtKB:Q96GE5] xref: EMBL:AC008758 xref: EMBL:AL832890 xref: EMBL:BC009517 xref: HGNC:HGNC:28071 xref: UniGene:Hs.546637 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058216 ! ZN799_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020948 name: ZNF800_human def: "Zinc finger protein 800 gene" [UniProtKB:Q2TB10] synonym: "PP902" EXACT [UniProtKB:Q2TB10] xref: EMBL:AF218032 xref: EMBL:BC110623 xref: EMBL:BC110624 xref: EMBL:CH471070 xref: HGNC:HGNC:27267 xref: UniGene:Hs.159006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056229 ! ZN800_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020949 name: ZNF805_human def: "Zinc finger protein 805 gene" [UniProtKB:Q5CZA5] xref: EMBL:AC005261 xref: EMBL:CR936617 xref: HGNC:HGNC:23272 xref: UniGene:Hs.22488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056419 ! ZN805_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020950 name: ZNF813_human def: "Zinc finger protein 813 gene" [UniProtKB:Q6ZN06] xref: EMBL:AC022137 xref: EMBL:AK131422 xref: HGNC:HGNC:33257 xref: UniGene:Hs.705729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057001 ! ZN813_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020951 name: ZNF818P_human def: "Putative zinc finger protein 818 gene" [UniProtKB:Q6ZRF7] synonym: "ZNF818" EXACT [UniProtKB:Q6ZRF7] xref: EMBL:AK128250 xref: HGNC:HGNC:33265 xref: UniGene:Hs.444446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057039 ! ZN818_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020952 name: ZNF821_human def: "Zinc finger protein 821 gene" [UniProtKB:O75541] xref: EMBL:AC009127 xref: EMBL:AF070588 xref: EMBL:BC012116 xref: EMBL:CH471166 xref: HGNC:HGNC:28043 xref: UniGene:Hs.643531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054649 ! ZN821_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020953 name: ZNF823_human def: "Zinc finger protein 823 gene" [UniProtKB:P16415] synonym: "ZFP36" EXACT [UniProtKB:P16415] xref: EMBL:BC052597 xref: EMBL:BC063560 xref: EMBL:X51760 xref: HGNC:HGNC:30936 xref: UniGene:Hs.142167 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055050 ! ZN823_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020954 name: ZNF826_human def: "Zinc finger protein 826 gene" [UniProtKB:Q6ZT77] xref: EMBL:AC008554 xref: EMBL:AK126842 xref: HGNC:HGNC:33875 xref: UniGene:Hs.515696 xref: UniGene:Hs.631635 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057067 ! ZN826_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020955 name: ZNF827_human def: "Zinc finger protein 827 gene" [UniProtKB:Q17R98] xref: EMBL:AF450485 xref: EMBL:AK091130 xref: EMBL:BC117407 xref: HGNC:HGNC:27193 xref: UniGene:Hs.133916 xref: UniGene:Hs.633543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056183 ! ZN827_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020956 name: ZNF829_human def: "Zinc finger protein 829 gene" [UniProtKB:Q3KNS6] xref: EMBL:AK130969 xref: EMBL:BC107131 xref: EMBL:BC107132 xref: EMBL:BX538288 xref: HGNC:HGNC:34032 xref: UniGene:Hs.124047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056250 ! ZN829_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020957 name: ZNF10_human def: "Zinc finger protein 10 gene" [UniProtKB:P21506] synonym: "KOX1" EXACT [UniProtKB:P21506] xref: EMBL:BC024182 xref: EMBL:X52332 xref: HGNC:HGNC:12879 xref: UniGene:Hs.507355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055132 ! ZNF10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020958 name: ZNF12_human def: "Zinc finger protein 12 gene" [UniProtKB:P17014] synonym: "GIOT3" EXACT [UniProtKB:P17014] synonym: "KOX3" EXACT [UniProtKB:P17014] synonym: "ZNF325" EXACT [UniProtKB:P17014] xref: EMBL:AB021643 xref: EMBL:BC154414 xref: EMBL:X52334 xref: HGNC:HGNC:12902 xref: UniGene:Hs.431471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054148 ! A8WFQ8_HUMAN relationship: codes_for CCO:B0055063 ! ZNF12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020959 name: ZNF14_human def: "Zinc finger protein 14 gene" [UniProtKB:P17017] synonym: "GIOT4" EXACT [UniProtKB:P17017] synonym: "KOX6" EXACT [UniProtKB:P17017] xref: EMBL:AB021644 xref: EMBL:X52337 xref: HGNC:HGNC:12924 xref: UniGene:Hs.659932 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055064 ! ZNF14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020960 name: ZNF16_human def: "Zinc finger protein 16 gene" [UniProtKB:P17020] synonym: "KOX9" EXACT [UniProtKB:P17020] xref: EMBL:BC010996 xref: EMBL:X52340 xref: HGNC:HGNC:12947 xref: UniGene:Hs.493225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055066 ! ZNF16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020961 name: ZNF17_human def: "Zinc finger protein 17 gene" [UniProtKB:P17021] synonym: "KIAA1947" EXACT [UniProtKB:P17021] synonym: "KOX10" EXACT [UniProtKB:P17021] xref: EMBL:AB075827 xref: EMBL:AC003002 xref: EMBL:AK097123 xref: EMBL:X52341 xref: HGNC:HGNC:12958 xref: UniGene:Hs.657353 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055067 ! ZNF17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020962 name: ZNF18_human def: "Zinc finger protein 18 gene" [UniProtKB:P17022] synonym: "HDSG1" EXACT [UniProtKB:P17022] synonym: "KOX11" EXACT [UniProtKB:P17022] synonym: "ZKSCAN6" EXACT [UniProtKB:P17022] xref: EMBL:AK092656 xref: EMBL:AY491053 xref: EMBL:BC036096 xref: EMBL:X52342 xref: HGNC:HGNC:12969 xref: UniGene:Hs.370473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055068 ! ZNF18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020963 name: ZNF20_human def: "Zinc finger protein 20 gene" [UniProtKB:P17024] synonym: "KOX13" EXACT [UniProtKB:P17024] xref: EMBL:AL080125 xref: EMBL:X52344 xref: HGNC:HGNC:12992 xref: UniGene:Hs.512823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055069 ! ZNF20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020964 name: ZNF22_human def: "Zinc finger protein 22 gene" [UniProtKB:P17026] synonym: "KOX15" EXACT [UniProtKB:P17026] synonym: "KROX26" EXACT [UniProtKB:P17026] xref: EMBL:AY137767 xref: EMBL:BC010642 xref: EMBL:BC041139 xref: EMBL:BC053687 xref: EMBL:BT009806 xref: EMBL:M77172 xref: EMBL:S50223 xref: EMBL:X52346 xref: HGNC:HGNC:13012 xref: UniGene:Hs.462693 xref: UniGene:Hs.655124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055071 ! ZNF22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020965 name: ZNF23_human def: "Zinc finger protein 23 gene" [UniProtKB:P17027] synonym: "KOX16" EXACT [UniProtKB:P17027] synonym: "ZNF359" EXACT [UniProtKB:P17027] xref: EMBL:AF507946 xref: EMBL:AL080123 xref: EMBL:BC007256 xref: EMBL:BT007400 xref: EMBL:X52347 xref: HGNC:HGNC:13023 xref: UniGene:Hs.656643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055072 ! ZNF23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020966 name: ZNF25_human def: "Zinc finger protein 25 gene" [UniProtKB:P17030] synonym: "KOX19" EXACT [UniProtKB:P17030] xref: EMBL:AJ491696 xref: EMBL:AK056452 xref: EMBL:AL117337 xref: EMBL:AL834125 xref: EMBL:BC036038 xref: EMBL:X52350 xref: HGNC:HGNC:13043 xref: UniGene:Hs.499429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055074 ! ZNF25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020967 name: ZNF28_human def: "Zinc finger protein 28 gene" [UniProtKB:P17035] synonym: "KOX24" EXACT [UniProtKB:P17035] xref: EMBL:AK131368 xref: EMBL:AK131574 xref: EMBL:BC070146 xref: EMBL:BX640767 xref: EMBL:CR933598 xref: EMBL:X52355 xref: HGNC:HGNC:13073 xref: UniGene:Hs.554778 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055076 ! ZNF28_HUMAN relationship: codes_for CCO:B0056851 ! Q6NSH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020968 name: ZNF2_human def: "Zinc finger protein 2 gene" [UniProtKB:Q9BSG1] synonym: "ZNF661" EXACT [UniProtKB:Q9BSG1] xref: EMBL:AC092835 xref: EMBL:AK315829 xref: EMBL:BC005068 xref: EMBL:BC009976 xref: EMBL:CH471219 xref: EMBL:X60152 xref: HGNC:HGNC:12991 xref: UniGene:Hs.590916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054083 ! A8MWV7_HUMAN relationship: codes_for CCO:B0054160 ! B0AZN8_HUMAN relationship: codes_for CCO:B0058505 ! ZNF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020969 name: ZNF30_human def: "Zinc finger protein 30 gene" [UniProtKB:P17039] synonym: "KOX28" EXACT [UniProtKB:P17039] xref: EMBL:AK290435 xref: EMBL:BC142996 xref: EMBL:BX640666 xref: EMBL:X52359 xref: HGNC:HGNC:13090 xref: UniGene:Hs.112556 xref: UniGene:Hs.657402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053776 ! A5PLP1_HUMAN relationship: codes_for CCO:B0055079 ! ZNF30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020970 name: ZNF32_human def: "Zinc finger protein 32 gene" [UniProtKB:P17041] synonym: "KOX30" EXACT [UniProtKB:P17041] xref: EMBL:AL645634 xref: EMBL:BC022842 xref: EMBL:U69645 xref: EMBL:X52361 xref: HGNC:HGNC:13095 xref: UniGene:Hs.522885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055080 ! ZNF32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020971 name: ZNF34_human def: "Zinc finger protein 34 gene" [UniProtKB:Q8IZ26] synonym: "KOX32" EXACT [UniProtKB:Q8IZ26] xref: EMBL:AL833814 xref: EMBL:BC004480 xref: EMBL:BC028136 xref: HGNC:HGNC:13098 xref: UniGene:Hs.631854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057396 ! ZNF34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020972 name: ZNF35_human def: "Zinc finger protein 35 gene" [UniProtKB:P13682] xref: EMBL:BC013597 xref: EMBL:BT006962 xref: EMBL:L35269 xref: EMBL:M76702 xref: EMBL:M76703 xref: EMBL:X07289 xref: HGNC:HGNC:13099 xref: UniGene:Hs.288658 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055017 ! ZNF35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020973 name: ZNF3_human def: "Zinc finger protein 3 gene" [UniProtKB:P17036] synonym: "KOX25" EXACT [UniProtKB:P17036] xref: EMBL:AF193057 xref: EMBL:AF217988 xref: EMBL:AK000223 xref: EMBL:BC011887 xref: EMBL:BC013603 xref: EMBL:CH236956 xref: EMBL:CH471091 xref: EMBL:X07290 xref: EMBL:X52356 xref: EMBL:X60153 xref: HGNC:HGNC:13089 xref: UniGene:Hs.435302 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053757 ! A4D2A4_HUMAN relationship: codes_for CCO:B0055077 ! ZNF3_HUMAN relationship: codes_for CCO:B0058789 ! Q9HBR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020974 name: ZNF41_human def: "Zinc finger protein 41 gene" [UniProtKB:P51814] xref: EMBL:AJ010017 xref: EMBL:AJ010018 xref: EMBL:AJ010019 xref: EMBL:AJ010020 xref: EMBL:AJ010021 xref: EMBL:AJ010022 xref: EMBL:AJ010023 xref: EMBL:AL590223 xref: EMBL:AL590283 xref: EMBL:BC015023 xref: EMBL:M92443 xref: EMBL:X60155 xref: HGNC:HGNC:13107 xref: UniGene:Hs.496074 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054276 ! B1AQ29_HUMAN relationship: codes_for CCO:B0055481 ! ZNF41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020975 name: ZNF43_human def: "Zinc finger protein 43 gene" [UniProtKB:P17038] synonym: "KOX27" EXACT [UniProtKB:P17038] synonym: "ZNF39" EXACT [UniProtKB:P17038] synonym: "ZNF39L1" EXACT [UniProtKB:P17038] xref: EMBL:BC006528 xref: EMBL:M61869 xref: EMBL:X52358 xref: EMBL:X59244 xref: HGNC:HGNC:13109 xref: UniGene:Hs.534365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055078 ! ZNF43_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020976 name: ZNF44_human def: "Zinc finger protein 44 gene" [UniProtKB:P15621] synonym: "KOX7" EXACT [UniProtKB:P15621] synonym: "ZNF58" EXACT [UniProtKB:P15621] xref: EMBL:AB021642 xref: EMBL:AC012618 xref: EMBL:AK297528 xref: EMBL:BC032246 xref: EMBL:CH471106 xref: EMBL:X16281 xref: EMBL:X52338 xref: HGNC:HGNC:13110 xref: UniGene:Hs.296731 xref: UniGene:Hs.656794 xref: UniGene:Hs.693933 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055040 ! ZNF44_HUMAN relationship: codes_for CCO:B0057476 ! Q8N5K7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020977 name: ZNF45_human def: "Zinc finger protein 45 gene" [UniProtKB:Q02386] synonym: "KOX5" EXACT [UniProtKB:Q02386] synonym: "ZNF13" EXACT [UniProtKB:Q02386] xref: EMBL:AC035150 xref: EMBL:BC037575 xref: EMBL:L75847 xref: EMBL:M67509 xref: EMBL:X52336 xref: HGNC:HGNC:13111 xref: UniGene:Hs.381285 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055708 ! ZNF45_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020978 name: ZNF57_human def: "Zinc finger protein 57 gene" [UniProtKB:Q68EA5] synonym: "ZNF424" EXACT [UniProtKB:Q68EA5] xref: EMBL:AC119403 xref: EMBL:BC028974 xref: EMBL:BX537601 xref: HGNC:HGNC:13125 xref: UniGene:Hs.591378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054115 ! A8MY82_HUMAN relationship: codes_for CCO:B0056709 ! ZNF57_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020979 name: ZNF66_human def: "Zinc finger protein 66 gene" [UniProtKB:Q6ZN08] xref: EMBL:AC010329 xref: EMBL:AK131420 xref: EMBL:M88375 xref: HGNC:HGNC:13135 xref: UniGene:Hs.658748 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057002 ! ZNF66_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020980 name: ZNF69_human def: "Zinc finger protein 69 gene" [UniProtKB:Q9UC07] xref: EMBL:AC008770 xref: EMBL:AK001669 xref: EMBL:BC051309 xref: EMBL:X60076 xref: HGNC:HGNC:13138 xref: UniGene:Hs.661955 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059095 ! ZNF69_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020981 name: ZNF70_human def: "Zinc finger protein 70 gene" [UniProtKB:Q9UC06] xref: EMBL:AB050771 xref: EMBL:BC040161 xref: EMBL:CR456615 xref: EMBL:X60077 xref: HGNC:HGNC:13140 xref: UniGene:Hs.382874 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059094 ! ZNF70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020982 name: ZNF71_human def: "Endothelial zinc finger protein induced by tumor necrosis factor alpha gene" [UniProtKB:Q9NQZ8] synonym: "EZFIT" EXACT [UniProtKB:Q9NQZ8] xref: EMBL:AC007228 xref: EMBL:AF269249 xref: EMBL:BC014280 xref: EMBL:M88357 xref: EMBL:X60074 xref: HGNC:HGNC:13141 xref: UniGene:Hs.301431 xref: UniGene:Hs.600391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058881 ! ZNF71_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020983 name: ZNF73_human def: "Zinc finger protein 73 gene" [UniProtKB:O43830] synonym: "ZNF186" EXACT [UniProtKB:O43830] xref: EMBL:X60075 xref: EMBL:Y10929 xref: HGNC:HGNC:13143 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054524 ! ZNF73_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020984 name: ZNF74_human def: "Zinc finger protein 74 gene" [UniProtKB:Q16587] xref: EMBL:AF072557 xref: EMBL:AF072562 xref: EMBL:AF072567 xref: EMBL:BC013395 xref: EMBL:CR456616 xref: EMBL:X63182 xref: EMBL:X71623 xref: EMBL:X92715 xref: HGNC:HGNC:13144 xref: UniGene:Hs.517418 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056155 ! ZNF74_HUMAN relationship: codes_for CCO:B0056921 ! Q6PJP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020985 name: ZNF76_human def: "Zinc finger protein 76 gene" [UniProtKB:P36508] synonym: "D6S229E" EXACT [UniProtKB:P36508] synonym: "ZNF523" EXACT [UniProtKB:P36508] xref: EMBL:BC000133 xref: EMBL:BC002549 xref: EMBL:BT007316 xref: EMBL:M91592 xref: HGNC:HGNC:13149 xref: UniGene:Hs.388024 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055309 ! ZNF76_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020986 name: ZNF77_human def: "Zinc finger protein 77 gene" [UniProtKB:Q15935] xref: EMBL:AL365370 xref: EMBL:BC043354 xref: EMBL:BC062561 xref: EMBL:X65230 xref: HGNC:HGNC:13150 xref: UniGene:Hs.38004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056121 ! ZNF77_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020987 name: ZNF79_human def: "Zinc finger protein 79 gene" [UniProtKB:Q15937] xref: EMBL:AK054606 xref: EMBL:AL445222 xref: EMBL:BC062309 xref: EMBL:X65232 xref: HGNC:HGNC:13153 xref: UniGene:Hs.522399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056122 ! ZNF79_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020988 name: ZNF80_human def: "Zinc finger protein 80 gene" [UniProtKB:P51504] xref: EMBL:BC069606 xref: EMBL:BC069826 xref: EMBL:BC129925 xref: EMBL:CH471052 xref: EMBL:X65233 xref: HGNC:HGNC:13155 xref: UniGene:Hs.271079 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055466 ! ZNF80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020989 name: ZNF83_human def: "Zinc finger protein 83 gene" [UniProtKB:P51522] synonym: "ZNF816B" EXACT [UniProtKB:P51522] xref: EMBL:M27877 xref: HGNC:HGNC:13158 xref: UniGene:Hs.467210 xref: UniGene:Hs.659798 xref: UniGene:Hs.665751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017103 ! ZNF83_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020990 name: ZNF84_human def: "Zinc finger protein 84 gene" [UniProtKB:P51523] xref: EMBL:BC036656 xref: EMBL:BC048350 xref: EMBL:BC062552 xref: EMBL:M27878 xref: EMBL:X60156 xref: HGNC:HGNC:13159 xref: UniGene:Hs.654730 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055467 ! ZNF84_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020991 name: ZNF85_human def: "Zinc finger protein 85 gene" [UniProtKB:Q03923] xref: EMBL:AC008739 xref: EMBL:BC068066 xref: EMBL:M61866 xref: EMBL:M61868 xref: EMBL:U35376 xref: HGNC:HGNC:13160 xref: UniGene:Hs.37138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032357 ! Q6NVI0_HUMAN relationship: codes_for CCO:B0055727 ! ZNF85_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020992 name: ZNF8_human def: "Zinc finger protein 8 gene" [UniProtKB:P17098] xref: EMBL:BC039323 xref: EMBL:M29581 xref: HGNC:HGNC:13154 xref: UniGene:Hs.590941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055083 ! ZNF8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020993 name: ZNF90_human def: "Zinc finger protein 90 gene" [UniProtKB:Q03938] xref: EMBL:CN386341 xref: EMBL:M61870 xref: HGNC:HGNC:13165 xref: UniGene:Hs.662176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055729 ! ZNF90_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020994 name: ZNF91_human def: "Zinc finger protein 91 gene" [UniProtKB:Q05481] xref: EMBL:AC010300 xref: EMBL:L11672 xref: EMBL:M61871 xref: HGNC:HGNC:13166 xref: UniGene:Hs.654471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054123 ! A8MYJ4_HUMAN relationship: codes_for CCO:B0055742 ! ZNF91_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020995 name: ZNF93_human def: "Zinc finger protein 93 gene" [UniProtKB:P35789] synonym: "ZNF505" EXACT [UniProtKB:P35789] xref: EMBL:AC007204 xref: EMBL:AC011477 xref: EMBL:AK022550 xref: EMBL:AK096342 xref: EMBL:BC070372 xref: EMBL:BC107581 xref: EMBL:M61873 xref: HGNC:HGNC:13169 xref: UniGene:Hs.301059 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032369 ! Q6NS90_HUMAN relationship: codes_for CCO:B0055302 ! ZNF93_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020997 name: ZNHIT3_human def: "Zinc finger HIT domain-containing protein 3 gene" [UniProtKB:Q15649] synonym: "TRIP3" EXACT [UniProtKB:Q15649] xref: EMBL:AF400652 xref: EMBL:BC017931 xref: EMBL:L40410 xref: HGNC:HGNC:12309 xref: UniGene:Hs.2210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056091 ! ZNHI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020998 name: SLC30A9_human def: "Zinc transporter 9 gene" [UniProtKB:Q6PML9] synonym: "C4orf1" EXACT [UniProtKB:Q6PML9] synonym: "HUEL" EXACT [UniProtKB:Q6PML9] xref: EMBL:AC113151 xref: EMBL:AF006621 xref: EMBL:AY319413 xref: EMBL:AY594282 xref: EMBL:BC007732 xref: EMBL:BC016949 xref: EMBL:BC022981 xref: HGNC:HGNC:1329 xref: UniGene:Hs.479634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056924 ! ZNT9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0020999 name: ZSCAN10_human def: "Zinc finger and SCAN domain-containing protein 10 gene" [UniProtKB:Q96SZ4] synonym: "ZNF206" EXACT [UniProtKB:Q96SZ4] xref: EMBL:AK027455 xref: HGNC:HGNC:12997 xref: UniGene:Hs.334515 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058397 ! ZSC10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021000 name: ZSCAN12_human def: "Zinc finger and SCAN domain-containing protein 12 gene" [UniProtKB:O43309] synonym: "KIAA0426" EXACT [UniProtKB:O43309] synonym: "ZNF305" EXACT [UniProtKB:O43309] synonym: "ZNF96" EXACT [UniProtKB:O43309] xref: EMBL:AB007886 xref: EMBL:BC041661 xref: EMBL:Z98745 xref: HGNC:HGNC:13172 xref: UniGene:Hs.134816 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054470 ! ZSC12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021001 name: ZSCAN18_human def: "Zinc finger and SCAN domain-containing protein 18 gene" [UniProtKB:Q8TBC5] synonym: "ZNF447" EXACT [UniProtKB:Q8TBC5] xref: EMBL:AK022957 xref: EMBL:AY280799 xref: EMBL:BC006205 xref: EMBL:BC022846 xref: HGNC:HGNC:21037 xref: UniGene:Hs.235390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057901 ! ZSC18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021002 name: ZSCAN20_human def: "Zinc finger and SCAN domain-containing protein 20 gene" [UniProtKB:P17040] synonym: "KOX29" EXACT [UniProtKB:P17040] synonym: "ZNF31" EXACT [UniProtKB:P17040] synonym: "ZNF360" EXACT [UniProtKB:P17040] xref: EMBL:AL138837 xref: EMBL:BC008827 xref: EMBL:BC011404 xref: EMBL:CH471059 xref: EMBL:X52360 xref: HGNC:HGNC:13093 xref: UniGene:Hs.442705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029281 ! Q96FA9_HUMAN relationship: codes_for CCO:B0029283 ! ZSC20_HUMAN relationship: codes_for CCO:B0029287 ! A6NJN6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021003 name: ZSCAN21_human def: "Zinc finger and SCAN domain-containing protein 21 gene" [UniProtKB:Q9Y5A6] synonym: "ZFP38" EXACT [UniProtKB:Q9Y5A6] synonym: "ZNF38" EXACT [UniProtKB:Q9Y5A6] xref: EMBL:AF155100 xref: EMBL:AL136865 xref: EMBL:BC047309 xref: HGNC:HGNC:13104 xref: UniGene:Hs.632294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059375 ! ZSC21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021004 name: ZSCAN22_human def: "Zinc finger and SCAN domain-containing protein 22 gene" [UniProtKB:P10073] synonym: "HKR2" EXACT [UniProtKB:P10073] synonym: "ZNF50" EXACT [UniProtKB:P10073] xref: EMBL:AK128716 xref: EMBL:BC101630 xref: EMBL:BC112277 xref: EMBL:BX537741 xref: EMBL:M88360 xref: HGNC:HGNC:4929 xref: UniGene:Hs.388162 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054967 ! ZSC22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021005 name: ZSCAN23_human def: "Zinc finger and SCAN domain-containing protein 23 gene" [UniProtKB:Q3MJ62] synonym: "ZNF390" EXACT [UniProtKB:Q3MJ62] synonym: "ZNF453" EXACT [UniProtKB:Q3MJ62] xref: EMBL:BC101557 xref: EMBL:BC101559 xref: EMBL:Z98745 xref: HGNC:HGNC:21193 xref: UniGene:Hs.376873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056265 ! ZSC23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021006 name: ZSCAN29_human def: "Zinc finger and SCAN domain-containing protein 29 gene" [UniProtKB:Q8IWY8] synonym: "ZNF690" EXACT [UniProtKB:Q8IWY8] xref: EMBL:AF525399 xref: EMBL:AK093186 xref: EMBL:BC109270 xref: EMBL:BC109271 xref: HGNC:HGNC:26673 xref: UniGene:Hs.418287 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057366 ! ZSC29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021007 name: ZSCAN1_human def: "Zinc finger and SCAN domain-containing protein 1 gene" [UniProtKB:Q8NBB4] xref: EMBL:AK091098 xref: EMBL:AY280370 xref: EMBL:BC048099 xref: HGNC:HGNC:23712 xref: UniGene:Hs.643437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057557 ! ZSCA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021008 name: ZSCAN2_human def: "Zinc finger and SCAN domain-containing protein 2 gene" [UniProtKB:Q7Z7L9] synonym: "ZFP29" EXACT [UniProtKB:Q7Z7L9] xref: EMBL:AC048382 xref: EMBL:AK000602 xref: EMBL:AK128624 xref: EMBL:AY262259 xref: EMBL:BC041620 xref: HGNC:HGNC:20994 xref: UniGene:Hs.594023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053829 ! A6NG83_HUMAN relationship: codes_for CCO:B0057219 ! ZSCA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021009 name: ZSCAN4_human def: "Zinc finger and SCAN domain-containing protein 4 gene" [UniProtKB:Q8NAM6] synonym: "ZNF494" EXACT [UniProtKB:Q8NAM6] xref: EMBL:AK092424 xref: EMBL:BC101738 xref: EMBL:BC101740 xref: HGNC:HGNC:23709 xref: UniGene:Hs.469663 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057548 ! ZSCA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021010 name: ZXDA_human def: "Zinc finger X-linked protein ZXDA gene" [UniProtKB:P98168] xref: EMBL:AL034396 xref: EMBL:BC059356 xref: EMBL:L14787 xref: HGNC:HGNC:13198 xref: UniGene:Hs.591214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055672 ! ZXDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021011 name: ZXDB_human def: "Zinc finger X-linked protein ZXDB gene" [UniProtKB:P98169] xref: EMBL:AL031115 xref: EMBL:L14788 xref: EMBL:Z99130 xref: HGNC:HGNC:13199 xref: UniGene:Hs.156257 xref: UniGene:Hs.649423 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055673 ! ZXDB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021012 name: ZXDC_human def: "Zinc finger protein ZXDC gene" [UniProtKB:Q2QGD7] synonym: "ZXDL" EXACT [UniProtKB:Q2QGD7] xref: EMBL:AK092101 xref: EMBL:AY936556 xref: EMBL:BC002940 xref: EMBL:BC012729 xref: EMBL:DQ079590 xref: HGNC:HGNC:28160 xref: UniGene:Hs.440049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056223 ! ZXDC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021013 name: ZZZ3_human def: "ZZ-type zinc finger-containing protein 3 gene" [UniProtKB:Q8IYH5] xref: EMBL:AK074119 xref: EMBL:AL080063 xref: EMBL:BC035079 xref: EMBL:BC035397 xref: EMBL:BC035818 xref: EMBL:BX640658 xref: EMBL:BX640766 xref: EMBL:BX641001 xref: HGNC:HGNC:24523 xref: UniGene:Hs.480506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057387 ! ZZZ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021014 name: CCR-5_human def: "CC-chemokine receptor gene" [UniProtKB:A0A502] xref: EMBL:AF009962 xref: HGNC:HGNC:1606 xref: UniGene:Hs.450802 xref: UniGene:Hs.536735 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053696 ! A0A502_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021015 name: ZFP37_human def: "Zinc finger protein 37 homolog (Mouse) gene" [UniProtKB:A0AVJ9] xref: EMBL:BC126390 xref: HGNC:HGNC:12863 xref: UniGene:Hs.150406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053699 ! A0AVJ9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021016 name: POM121C_human def: "POM121C protein gene" [UniProtKB:A1L4L9] xref: EMBL:BC130587 xref: EMBL:BC130589 xref: UniGene:Hs.436034 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053713 ! A1L4L9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021017 name: RP5-1100H13.1_human def: "OTTHUMP00000030968 gene" [UniProtKB:A2A2E9] synonym: "RP5-1100H13.1-005" EXACT [UniProtKB:A2A2E9] xref: EMBL:AL035419 xref: EMBL:AL049868 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053716 ! A2A2E9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021018 name: OR5U1_human def: "Olfactory receptor family 5 subfamily U member 1 gene" [UniProtKB:A2BEC2] synonym: "DAAP-191E6.3-001" EXACT [UniProtKB:A2BEC2] synonym: "DADB-246O10.5-001" EXACT [UniProtKB:A2BEC2] synonym: "DAMA-334F21.2-001" EXACT [UniProtKB:A2BEC2] synonym: "DASS-352F1.4-001" EXACT [UniProtKB:A2BEC2] xref: EMBL:BX005432 xref: EMBL:BX927232 xref: EMBL:CR753509 xref: EMBL:CR936918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053726 ! A2BEC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021019 name: LOC553158_human def: "PRR5-ARHGAP8 fusion gene" [UniProtKB:A2RU51] synonym: "ARHGAP8" EXACT [UniProtKB:A2RU51] synonym: "RP1-127B20.1-007" EXACT [UniProtKB:A2RU51] xref: EMBL:BC132755 xref: EMBL:BC132757 xref: EMBL:Z83838 xref: EMBL:Z93244 xref: UniGene:Hs.102336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053739 ! A2RU51_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021020 name: AVGR8_human def: "Autogenous vein graft remodeling associated protein 8 gene" [UniProtKB:A2VBQ3] xref: EMBL:AM492791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053741 ! A2VBQ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021021 name: LOC393004_human def: "Similar to dGTPase-mouse gene" [UniProtKB:A4D1S6] synonym: "tcag7.1187" EXACT [UniProtKB:A4D1S6] xref: EMBL:CH236950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053753 ! A4D1S6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021022 name: LOC389604_human def: "Similar to vasoactive intestinal peptide receptor 2 gene" [UniProtKB:A4D225] synonym: "tcag7.970" EXACT [UniProtKB:A4D225] xref: EMBL:CH236954 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053754 ! A4D225_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021023 name: OR6B1_human def: "Olfactory receptor, family 6, subfamily B, member 1 gene" [UniProtKB:A4D2G2] synonym: "tcag7.923" EXACT [UniProtKB:A4D2G2] xref: EMBL:CH236959 xref: UniGene:Hs.632031 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053758 ! A4D2G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021024 name: LOC402257_human def: "Similar to ELK1 gene" [UniProtKB:A4D2L0] synonym: "tcag7.968" EXACT [UniProtKB:A4D2L0] xref: EMBL:CH236960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053760 ! A4D2L0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021025 name: ZFP112_human def: "Zinc finger protein 112 homolog gene" [UniProtKB:Q9UJU3] synonym: "ZNF228" EXACT [UniProtKB:Q9UJU3] xref: EMBL:AC084239 xref: EMBL:AF198358 xref: EMBL:BC101753 xref: EMBL:CH471126 xref: HGNC:HGNC:13021 xref: UniGene:Hs.48589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053763 ! A4FU53_HUMAN relationship: codes_for CCO:B0059176 ! ZF112_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021026 name: DSCR1L2_human def: "Regulator of calcineurin 3 isoform 2,4,5 gene" [UniProtKB:A4GU14] xref: EMBL:AY906854 xref: EMBL:EF431960 xref: EMBL:EF467309 xref: EMBL:EF529733 xref: HGNC:HGNC:3042 xref: UniGene:Hs.656799 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053766 ! A4GU14_HUMAN relationship: codes_for CCO:B0053767 ! A4LA69_HUMAN relationship: codes_for CCO:B0056425 ! Q5ECL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021027 name: taf4b_human def: "TATA box binding protein (TBP)-associated factor 4B gene" [UniProtKB:A4PBF7] xref: EMBL:AB234096 xref: UniGene:Hs.369519 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053768 ! A4PBF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021028 name: PRDM7_V1_human def: "PRDM7 long isoform, variant 1 gene" [UniProtKB:A4Q9G8] xref: EMBL:AM690991 xref: UniGene:Hs.406695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053769 ! A4Q9G8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021029 name: PRDM7_V2_human def: "PRDM7 long isoform, variant 2 gene" [UniProtKB:A4Q9G9] xref: EMBL:AM690992 xref: UniGene:Hs.406695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053770 ! A4Q9G9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021030 name: LOC442421_human def: "LOC442421 protein gene" [UniProtKB:A4QMS5] xref: EMBL:BC042539 xref: EMBL:BC104192 xref: EMBL:BC104193 xref: EMBL:BC112986 xref: EMBL:BC112987 xref: UniGene:Hs.536982 xref: UniGene:Hs.585349 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053771 ! A4QMS5_HUMAN relationship: codes_for CCO:B0057338 ! Q8IV68_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021031 name: TBX4_human def: "TBX4 protein gene" [UniProtKB:A5PKU7] xref: EMBL:BC142620 xref: UniGene:Hs.143907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053774 ! A5PKU7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021032 name: TBC1D3E_human def: "TBC1 domain family member 3E/3F gene" [UniProtKB:A6NER0] xref: EMBL:AC027821 xref: HGNC:HGNC:19031 xref: HGNC:HGNC:27071 xref: HGNC:HGNC:28944 xref: UniGene:Hs.105891 xref: UniGene:Hs.631531 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053792 ! A6NDL0_HUMAN relationship: codes_for CCO:B0053809 ! TBC3E_HUMAN relationship: codes_for CCO:B0054101 ! A8MXQ6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021033 name: TBC1D3F_human def: "TBC1 domain family member 3E/3F gene" [UniProtKB:A6NER0] xref: EMBL:AC003976 xref: HGNC:HGNC:18257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053802 ! A6NE50_HUMAN relationship: codes_for CCO:B0053809 ! TBC3E_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021034 name: ATPIF1_human def: "ATPase inhibitor, mitochondrial precursor gene" [UniProtKB:Q9UII2] synonym: "ATPI" EXACT [UniProtKB:Q9UII2] xref: EMBL:AB029042 xref: EMBL:AL353622 xref: EMBL:AY005470 xref: EMBL:BC009677 xref: HGNC:HGNC:871 xref: UniGene:Hs.590908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053804 ! A6NE74_HUMAN relationship: codes_for CCO:B0063444 ! ATIF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021035 name: LAMA2_human def: "Putative uncharacterized protein LAMA2 gene" [UniProtKB:A6NF00] xref: EMBL:AL445439 xref: HGNC:HGNC:6482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053811 ! A6NF00_HUMAN relationship: codes_for CCO:B0053833 ! A6NGS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021036 name: ASB14_human def: "Putative uncharacterized protein ASB14 gene" [UniProtKB:A6NK59] xref: EMBL:AC093928 xref: HGNC:HGNC:19766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053879 ! A6NK59_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021037 name: ZNF75D_human def: "Putative uncharacterized protein ZNF75D (Zinc finger protein 75) (D8C6) gene" [UniProtKB:A6NK62] synonym: "RP13-210D15.7-003" EXACT [UniProtKB:A6NK62] synonym: "ZNF75" EXACT [UniProtKB:A6NK62] xref: EMBL:AL590282 xref: HGNC:HGNC:13145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0050223 ! A6NK62_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021038 name: PIK4CB_human def: "Phosphatidylinositol 4-kinase, catalytic, beta polypeptide gene" [UniProtKB:A6PVV8] synonym: "RP11-126K1.4-005" EXACT [UniProtKB:A6PVV8] xref: EMBL:AL391069 xref: EMBL:CH471121 xref: HGNC:HGNC:8984 xref: UniGene:Hs.632465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053928 ! A6PVV8_HUMAN relationship: codes_for CCO:B0056662 ! Q5VWB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021039 name: PRKAR1A/RARA fusion_human def: "Protein kinase A regulatory subunit type I/alpha-retinoic acid receptor alpha fusion protein isoform a gene" [UniProtKB:A6YCE1] xref: EMBL:EF428110 xref: EMBL:EF428111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053941 ! A6YCE1_HUMAN relationship: codes_for CCO:B0053942 ! A6YCE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021040 name: TBC1D4_human def: "TBC1D4 protein gene" [UniProtKB:A7E2X8] xref: EMBL:BC151239 xref: UniGene:Hs.210891 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053946 ! A7E2X8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021041 name: RAMP2_human def: "Receptor activity modifying protein 2 gene" [UniProtKB:A7L9S6] xref: EMBL:EF687002 xref: UniGene:Hs.514193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053948 ! A7L9S6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021042 name: CIC/DUX4 fusion_human def: "Capicua-like protein/double homeodomain 4 fusion protein gene" [UniProtKB:A7XAK3] xref: EMBL:DQ388764 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053950 ! A7XAK3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021043 name: SUCNR1_human def: "cDNA FLJ75637, highly similar to Homo sapiens succinate receptor 1 (SUCNR1), mRNA (Succinate receptor 1, isoform CRA_a) (Succinate receptor 1) gene" [UniProtKB:A8K305] synonym: "hCG_1645111" EXACT [UniProtKB:A8K305] xref: EMBL:AK290420 xref: EMBL:CH471052 xref: EMBL:EU432110 xref: UniGene:Hs.279575 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053960 ! A8K305_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021044 name: LOC125893_human def: "cDNA FLJ76721 gene" [UniProtKB:A8K7H5] synonym: "hCG_2036633" EXACT [UniProtKB:A8K7H5] xref: EMBL:AK291990 xref: EMBL:CH471135 xref: UniGene:Hs.655592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053976 ! A8K7H5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021045 name: CNTNAP4_human def: "Putative uncharacterized protein CNTNAP4 gene" [UniProtKB:A8MPQ3] xref: EMBL:AC010528 xref: HGNC:HGNC:18747 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053987 ! A8MPQ3_HUMAN relationship: codes_for CCO:B0054091 ! A8MX59_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021046 name: PRKD1_human def: "Serine/threonine-protein kinase D1 gene" [UniProtKB:Q15139] synonym: "PKD" EXACT [UniProtKB:Q15139] synonym: "PKD1" EXACT [UniProtKB:Q15139] synonym: "PRKCM" EXACT [UniProtKB:Q15139] xref: EMBL:AK314170 xref: EMBL:AL135858 xref: EMBL:CH471078 xref: EMBL:DQ485452 xref: EMBL:X75756 xref: HGNC:HGNC:9407 xref: UniGene:Hs.508999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054000 ! A8MQU9_HUMAN relationship: codes_for CCO:B0054127 ! A8MYR5_HUMAN relationship: codes_for CCO:B0056190 ! Q1KKQ2_HUMAN relationship: codes_for CCO:B0063240 ! KPCD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021047 name: OR52R1_human def: "Putative uncharacterized protein OR52R1 gene" [UniProtKB:A8MUM9] xref: EMBL:AC103710 xref: HGNC:HGNC:15235 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054042 ! A8MUM9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021048 name: TMBIM6_human def: "Putative uncharacterized protein TMBIM6 gene" [UniProtKB:A8MUR1] xref: EMBL:AC084037 xref: HGNC:HGNC:11723 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054043 ! A8MUR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021049 name: OR1N2_human def: "Putative uncharacterized protein OR1N2 gene" [UniProtKB:A8MWG5] xref: EMBL:AL359636 xref: HGNC:HGNC:15111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054079 ! A8MWG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021050 name: GPR179_human def: "Putative uncharacterized protein GPR179 gene" [UniProtKB:A8MWI1] xref: EMBL:AC115992 xref: HGNC:HGNC:31371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054080 ! A8MWI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021051 name: OR8A1_human def: "Putative uncharacterized protein OR8A1 gene" [UniProtKB:A8MY27] xref: EMBL:AP000916 xref: HGNC:HGNC:8469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054111 ! A8MY27_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021052 name: OR52H1_human def: "Putative uncharacterized protein OR52H1 gene" [UniProtKB:A8MY83] xref: EMBL:AC087380 xref: HGNC:HGNC:15218 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054116 ! A8MY83_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021053 name: ZNF300_human def: "Putative uncharacterized protein ZNF300 (Zinc finger protein 300, isoform CRA_e) gene" [UniProtKB:A8MY91] synonym: "hCG_1980728" EXACT [UniProtKB:A8MY91] xref: EMBL:AC010441 xref: EMBL:CH471062 xref: HGNC:HGNC:13091 xref: UniGene:Hs.134885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054119 ! A8MY91_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021054 name: ZNF765_human def: "Zinc finger protein 765 gene" [UniProtKB:Q7L2R6] xref: EMBL:AC022137 xref: EMBL:BC001610 xref: EMBL:BC017357 xref: EMBL:CH471135 xref: HGNC:HGNC:25092 xref: UniGene:Hs.705729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054122 ! A8MYG0_HUMAN relationship: codes_for CCO:B0057116 ! ZN765_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021055 name: MRGPRE_human def: "Putative uncharacterized protein MRGPRE (HCG2039161) gene" [UniProtKB:A8MZL3] synonym: "hCG_2039161" EXACT [UniProtKB:A8MZL3] xref: EMBL:AC109309 xref: EMBL:CH471158 xref: HGNC:HGNC:30694 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054144 ! A8MZL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021056 name: XXbac-BCX360G3.2-001_human def: "Novel protein gene" [UniProtKB:B0V386] synonym: "XXbac-BPG541D20.6-001" EXACT [UniProtKB:B0V386] xref: EMBL:CU024913 xref: EMBL:CU234142 xref: EMBL:CU459007 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054192 ! B0V386_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021057 name: LAMA3_human def: "Laminin subunit alpha-3 precursor gene" [UniProtKB:Q16787] synonym: "LAMNA" EXACT [UniProtKB:Q16787] xref: EMBL:AB107369 xref: EMBL:AC010754 xref: EMBL:AC067796 xref: EMBL:AC090366 xref: EMBL:AY327114 xref: EMBL:AY327115 xref: EMBL:AY327116 xref: EMBL:EF444992 xref: EMBL:L34155 xref: EMBL:X84900 xref: EMBL:X85107 xref: EMBL:X85108 xref: HGNC:HGNC:6483 xref: UniGene:Hs.436367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054195 ! B0YJ32_HUMAN relationship: codes_for CCO:B0054196 ! B0YJ33_HUMAN relationship: codes_for CCO:B0056963 ! Q6VU67_HUMAN relationship: codes_for CCO:B0056965 ! Q6VU69_HUMAN relationship: codes_for CCO:B0063514 ! LAMA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021058 name: PSCD4_human def: "Pleckstrin homology, Sec7 and coiled-coil domains 4 gene" [UniProtKB:B1AHH4] synonym: "RP1-63G5.4-014" EXACT [UniProtKB:B1AHH4] xref: EMBL:Z94160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054214 ! B1AHH4_HUMAN relationship: codes_for CCO:B0054215 ! B1AHH5_HUMAN relationship: codes_for CCO:B0054216 ! B1AHH6_HUMAN relationship: codes_for CCO:B0054217 ! B1AHH7_HUMAN relationship: codes_for CCO:B0054218 ! B1AHH8_HUMAN relationship: codes_for CCO:B0054219 ! B1AHI0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021059 name: AKAP2_human def: "A kinase (PRKA) anchor protein 2 gene" [UniProtKB:B1ALY0] synonym: "RP11-470J20.3-003" EXACT [UniProtKB:B1ALY0] xref: EMBL:AL158823 xref: EMBL:AL158829 xref: EMBL:AL353806 xref: EMBL:AL627225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054248 ! B1ALY0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021060 name: C9orf86_human def: "Chromosome 9 open reading frame 86 gene" [UniProtKB:B1AMX3] synonym: "RP11-216L13.9-001" EXACT [UniProtKB:B1AMX3] xref: EMBL:AL355987 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054257 ! B1AMX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021061 name: LPAR1_human def: "Lysophosphatidic acid receptor 1 gene" [UniProtKB:Q92633] synonym: "EDG2" EXACT [UniProtKB:Q92633] synonym: "LPA1" EXACT [UniProtKB:Q92633] xref: EMBL:AL442064 xref: EMBL:AY322546 xref: EMBL:BC030615 xref: EMBL:BC036034 xref: EMBL:U78192 xref: EMBL:U80811 xref: EMBL:Y09479 xref: HGNC:HGNC:3166 xref: UniGene:Hs.126667 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054268 ! B1AP63_HUMAN relationship: codes_for CCO:B0058076 ! LPAR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021062 name: N-TAF1_human def: "TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform gene" [UniProtKB:B1Q2X3] xref: EMBL:AB300418 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054289 ! B1Q2X3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021063 name: hMLH1_human def: "DNA mismatch repair protein gene" [UniProtKB:O00497] xref: EMBL:AF001359 xref: HGNC:HGNC:7127 xref: UniGene:Hs.195364 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054329 ! O00497_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021064 name: p65_human def: "Protein p65 gene" [UniProtKB:O43245] xref: EMBL:AJ002425 xref: UniGene:Hs.194790 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054461 ! O43245_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021065 name: WUGSC:H_DJ0320J15.1_human def: "WUGSC:H_DJ0320J15.1 protein (HCG1645130) gene" [UniProtKB:O43372] synonym: "hCG_1645130" EXACT [UniProtKB:O43372] xref: EMBL:AC004081 xref: EMBL:CH471120 xref: HGNC:HGNC:7556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054477 ! O43372_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021066 name: CMAR_human def: "Cell matrix adhesion regulator variant gene" [UniProtKB:O43535] xref: EMBL:AF034795 xref: EMBL:S70458 xref: HGNC:HGNC:11237 xref: UniGene:Hs.185597 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054487 ! O43535_HUMAN relationship: codes_for CCO:B0056126 ! Q16161_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021067 name: KARP-1_human def: "Ku86 autoantigen related protein 1 gene" [UniProtKB:O43594] xref: EMBL:AF039597 xref: HGNC:HGNC:12833 xref: UniGene:Hs.388739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054496 ! O43594_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021068 name: OR2H5P_human def: "Olfactory receptor-like protein gene" [UniProtKB:O43627] synonym: "OLFR 42B" EXACT [UniProtKB:O43627] xref: EMBL:AF042076 xref: HGNC:HGNC:8256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054505 ! O43627_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021069 name: CBP_human def: "CBP gene" [UniProtKB:O60424] xref: EMBL:AC004760 xref: HGNC:HGNC:2348 xref: UniGene:Hs.459759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024552 ! O60424_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021070 name: FTF_human def: "Alpha1-fetoprotein transcription factor short variant gene" [UniProtKB:O60587] xref: EMBL:AF049102 xref: HGNC:HGNC:7984 xref: UniGene:Hs.33446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054568 ! O60587_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021071 name: IEX-1L_human def: "Anti-death protein gene" [UniProtKB:O75353] xref: EMBL:AF039067 xref: EMBL:AF071596 xref: HGNC:HGNC:5392 xref: UniGene:Hs.591785 xref: UniGene:Hs.696650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054621 ! O75353_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021072 name: ranbp3_human def: "Ranbp3 protein gene" [UniProtKB:O75761] xref: EMBL:Y08699 xref: HGNC:HGNC:9850 xref: UniGene:Hs.531752 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054664 ! O75761_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021073 name: c-erbB-3_human def: "ErbB-3 R1 gene" [UniProtKB:O75810] xref: EMBL:U88357 xref: HGNC:HGNC:3431 xref: UniGene:Hs.118681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054670 ! O75810_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021074 name: KLRA1_human def: "Killer cell lectin-like receptor subfamily A member 1 (NK receptor Ly- 49L). gene" [UniProtKB:O75889] synonym: "hCG_27420" EXACT [UniProtKB:O75889] synonym: "LY49L" EXACT [UniProtKB:O75889] xref: EMBL:AF047445 xref: EMBL:BC069672 xref: EMBL:BC069734 xref: EMBL:BC101471 xref: EMBL:BC101473 xref: EMBL:CH471094 xref: HGNC:HGNC:6372 xref: UniGene:Hs.159297 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054675 ! O75889_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021075 name: SOX5P_human def: "SOX-29 protein gene" [UniProtKB:O95133] synonym: "SOX29" EXACT [UniProtKB:O95133] xref: EMBL:AF032454 xref: HGNC:HGNC:11202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054726 ! O95133_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021076 name: olfr89_human def: "Olfactory receptor 89 (Olfactory receptor OR6-17) gene" [UniProtKB:O95499] xref: EMBL:AJ132194 xref: EMBL:BK004435 xref: HGNC:HGNC:8271 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054769 ! O95499_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021077 name: pol_human def: "Reverse transcriptase gene" [UniProtKB:O95724] xref: EMBL:AF015994 xref: EMBL:AJ233629 xref: EMBL:AJ233632 xref: EMBL:DQ821442 xref: HGNC:HGNC:13915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054786 ! O95724_HUMAN relationship: codes_for CCO:B0054787 ! O95725_HUMAN relationship: codes_for CCO:B0055817 ! Q0PKG6_HUMAN relationship: codes_for CCO:B0057101 ! Q71VD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021078 name: PMS2L15_human def: "PMS2L15 protein gene" [UniProtKB:O95745] xref: EMBL:AB017006 xref: HGNC:HGNC:9127 xref: UniGene:Hs.292996 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054789 ! O95745_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021079 name: LIBC_human def: "Lost in inflammatory breast cancer tumor suppressor protein gene" [UniProtKB:O95958] synonym: "hCG_34804" EXACT [UniProtKB:O95958] synonym: "RP1-142L7.3-004" EXACT [UniProtKB:O95958] synonym: "WISP3" EXACT [UniProtKB:O95958] xref: EMBL:AF143679 xref: EMBL:CH471051 xref: EMBL:Z99289 xref: HGNC:HGNC:12771 xref: UniGene:Hs.558428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054808 ! O95958_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021080 name: hCG_2001537_human def: "G18 (Putative uncharacterized protein) (HCG2001537, isoform CRA_f) gene" [UniProtKB:P78548] xref: EMBL:CH471081 xref: EMBL:U89335 xref: EMBL:U89336 xref: HGNC:HGNC:13945 xref: UniGene:Hs.520046 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055651 ! P78548_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021081 name: CIB2_human def: "CIB2 protein gene" [UniProtKB:Q05BT6] synonym: "hCG_38933" EXACT [UniProtKB:Q05BT6] xref: EMBL:BC033108 xref: EMBL:CH471136 xref: HGNC:HGNC:24579 xref: UniGene:Hs.129867 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055752 ! Q05BT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021082 name: TC4_human def: "TC4 protein gene" [UniProtKB:Q0EFC9] xref: EMBL:AB103599 xref: HGNC:HGNC:21631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055810 ! Q0EFC9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021083 name: ECT2_human def: "Epithelial cell transforming sequence 2 oncogene protein splice variant b gene" [UniProtKB:Q0MT80] xref: EMBL:DQ847274 xref: HGNC:HGNC:3155 xref: UniGene:Hs.518299 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055814 ! Q0MT80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021084 name: C3orf41_human def: "C3orf41 protein gene" [UniProtKB:Q0VFW9] synonym: "hCG_2039480" EXACT [UniProtKB:Q0VFW9] xref: EMBL:BC118551 xref: EMBL:BC118662 xref: EMBL:CH471055 xref: HGNC:HGNC:24485 xref: UniGene:Hs.146346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055825 ! Q0VFW9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021085 name: NFI_human def: "Nuclear factor 1 gene" [UniProtKB:Q13051] xref: EMBL:U18760 xref: HGNC:HGNC:7788 xref: UniGene:Hs.257970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025422 ! Q13051_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021086 name: IL2_human def: "Interleukin 2 gene" [UniProtKB:Q13169] xref: EMBL:U25676 xref: HGNC:HGNC:6001 xref: UniGene:Hs.89679 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055883 ! Q13169_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021087 name: GATA-4_human def: "GATA-4 protein gene" [UniProtKB:Q13222] xref: EMBL:U28835 xref: HGNC:HGNC:4173 xref: UniGene:Hs.243987 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055888 ! Q13222_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021088 name: OSIL_human def: "Phosphotyrosine independent ligand p62B for the Lck SH2 domain B-cell isoform gene" [UniProtKB:Q13502] xref: EMBL:U46752 xref: HGNC:HGNC:11280 xref: UniGene:Hs.437277 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055919 ! Q13502_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021089 name: GSA_human def: "Alpha subunit of GsGTP binding protein gene" [UniProtKB:Q14455] xref: EMBL:X56009 xref: HGNC:HGNC:4392 xref: UniGene:Hs.125898 xref: UniGene:Hs.694849 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027558 ! Q14455_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021090 name: hCREM-1_human def: "HCREM 1alpha protein gene" [UniProtKB:Q14501] xref: EMBL:D14825 xref: HGNC:HGNC:2352 xref: UniGene:Hs.200250 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055988 ! Q14501_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021091 name: HOX2.8_human def: "HOX2.8 protein gene" [UniProtKB:Q14548] xref: EMBL:M73999 xref: HGNC:HGNC:5113 xref: UniGene:Hs.514289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055992 ! Q14548_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021092 name: VENTX1_human def: "HPX-42 protein gene" [UniProtKB:Q14560] synonym: "HPX-42" EXACT [UniProtKB:Q14560] xref: EMBL:X74864 xref: HGNC:HGNC:13638 xref: UniGene:Hs.543226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055993 ! Q14560_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021093 name: HSIL5R3_human def: "Interleukin-5 receptor type 3 gene" [UniProtKB:Q14632] xref: EMBL:X61178 xref: HGNC:HGNC:6017 xref: UniGene:Hs.68876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056005 ! Q14632_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021094 name: KBF2_human def: "H-2K binding factor-2 gene" [UniProtKB:Q14663] synonym: "pKBF-2" EXACT [UniProtKB:Q14663] xref: EMBL:D14041 xref: EMBL:L08904 xref: HGNC:HGNC:5724 xref: UniGene:Hs.479396 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056010 ! Q14663_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021095 name: max_human def: "cDNA FLJ76576, highly similar to Homo sapiens MYC associated factor X (MAX), transcript variant 5, mRNA gene" [UniProtKB:Q14803] synonym: "hCG_41671" EXACT [UniProtKB:Q14803] synonym: "MAX" EXACT [UniProtKB:Q14803] xref: EMBL:AK292630 xref: EMBL:CH471061 xref: EMBL:X66867 xref: HGNC:HGNC:6913 xref: UniGene:Hs.285354 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056016 ! Q14803_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021096 name: K222_human def: "K222 protein gene" [UniProtKB:Q14867] xref: EMBL:X77690 xref: UniGene:Hs.682316 xref: UniGene:Hs.701968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056020 ! Q14867_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021097 name: EPR1_human def: "Effector cell protease receptor 1 gene" [UniProtKB:Q14868] synonym: "EPR-1" EXACT [UniProtKB:Q14868] xref: EMBL:L26245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056021 ! Q14868_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021098 name: RET/PTC2_human def: "RET tyrosine kinase/cAMP protein kinase A subunit RI gene" [UniProtKB:Q15300] xref: EMBL:L03357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017343 ! Q15300_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021099 name: tb protein_human def: "CACCC box-binding protein gene" [UniProtKB:Q15552] xref: EMBL:L04282 xref: HGNC:HGNC:12933 xref: UniGene:Hs.592591 xref: UniGene:Hs.693585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056074 ! Q15552_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021100 name: tre_human def: "Oncogene gene" [UniProtKB:Q15635] xref: EMBL:X63547 xref: HGNC:HGNC:12629 xref: UniGene:Hs.448851 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056087 ! Q15635_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021101 name: pp52_human def: "Pp52 protein gene" [UniProtKB:Q16002] xref: EMBL:S58726 xref: HGNC:HGNC:6707 xref: UniGene:Hs.56729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056124 ! Q16002_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021102 name: INSAF_human def: "Insulin activator factor (Insulin control element-binding transcription factor). gene" [UniProtKB:Q16219] xref: EMBL:S73205 xref: HGNC:HGNC:6082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056128 ! Q16219_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021103 name: MM1_human def: "Clone MM1 product gene" [UniProtKB:Q16293] xref: EMBL:S76730 xref: HGNC:HGNC:9104 xref: UniGene:Hs.3989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056134 ! Q16293_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021104 name: 4R-MAP2_human def: "Microtubule-associated protein gene" [UniProtKB:Q16296] xref: EMBL:S76756 xref: HGNC:HGNC:6839 xref: UniGene:Hs.368281 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056135 ! Q16296_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021105 name: PMS2L4_human def: "Postmeiotic segregation increased 2-like protein 4. gene" [UniProtKB:Q16544] synonym: "hPMS6" EXACT [UniProtKB:Q16544] synonym: "PMS6" EXACT [UniProtKB:Q16544] xref: EMBL:D38438 xref: EMBL:D38500 xref: HGNC:HGNC:9129 xref: UniGene:Hs.658037 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056147 ! Q16544_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021106 name: PMS8_human def: "PMS8 protein (HCG2023604, isoform CRA_a) (HPMS8 protein) gene" [UniProtKB:Q16590] synonym: "hCG_2023604" EXACT [UniProtKB:Q16590] synonym: "hPMS8" EXACT [UniProtKB:Q16590] xref: EMBL:CH471091 xref: EMBL:D38440 xref: EMBL:D38503 xref: HGNC:HGNC:9123 xref: UniGene:Hs.634244 xref: UniGene:Hs.654752 xref: UniGene:Hs.661055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056156 ! Q16590_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021107 name: PMS7_human def: "PMS7 protein (HPMS7 protein) gene" [UniProtKB:Q16673] synonym: "hPMS7" EXACT [UniProtKB:Q16673] xref: EMBL:D38439 xref: EMBL:D38501 xref: HGNC:HGNC:9130 xref: UniGene:Hs.292996 xref: UniGene:Hs.647025 xref: UniGene:Hs.662458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056174 ! Q16673_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021108 name: ZNF285A_human def: "Zinc finger protein 285A gene" [UniProtKB:Q17RJ3] xref: EMBL:BC117300 xref: EMBL:BC117302 xref: HGNC:HGNC:13079 xref: UniGene:Hs.48589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056184 ! Q17RJ3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021109 name: MLL/AF6 fusion_human def: "MLL/AF6 fusion protein gene" [UniProtKB:Q1WD23] xref: EMBL:DQ387206 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056196 ! Q1WD23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021110 name: AVGR5_human def: "Autogenous vein graft remodeling associated protein 5 gene" [UniProtKB:Q2A130] xref: EMBL:AM233521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025485 ! Q2A130_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021111 name: AVGR4_human def: "Autogenous vein graft remodeling associated protein 4 gene" [UniProtKB:Q2HPP7] xref: EMBL:AM231187 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056201 ! Q2HPP7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021112 name: OR13A1_human def: "OR13A1 protein (HCG1647786) gene" [UniProtKB:Q2M3M4] synonym: "hCG_1647786" EXACT [UniProtKB:Q2M3M4] xref: EMBL:BC104853 xref: EMBL:BC104855 xref: EMBL:CH471160 xref: HGNC:HGNC:14772 xref: UniGene:Hs.532435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056211 ! Q2M3M4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021113 name: PAX7B_human def: "PAX7 transcriptional factor isoform B gene" [UniProtKB:Q2PJS5] xref: EMBL:DQ322591 xref: HGNC:HGNC:8621 xref: UniGene:Hs.113253 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056220 ! Q2PJS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021114 name: JRKL_human def: "Jerky homolog-like (Mouse) gene" [UniProtKB:Q32MC2] synonym: "hCG_19793" EXACT [UniProtKB:Q32MC2] xref: EMBL:BC109202 xref: EMBL:CH471065 xref: HGNC:HGNC:6200 xref: UniGene:Hs.105940 xref: UniGene:Hs.684437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056238 ! Q32MC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021115 name: BCL2L10_human def: "BCL2-like 10 (Apoptosis facilitator) gene" [UniProtKB:Q3SX80] xref: EMBL:BC104443 xref: HGNC:HGNC:993 xref: UniGene:Hs.283672 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056267 ! Q3SX80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021116 name: GPR50_human def: "GPR50 protein gene" [UniProtKB:Q3ZAR0] xref: EMBL:AY114102 xref: EMBL:BC103696 xref: EMBL:BC105683 xref: HGNC:HGNC:4506 xref: UniGene:Hs.567390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056280 ! Q3ZAR0_HUMAN relationship: codes_for CCO:B0057174 ! Q7Z581_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021117 name: FAM13B1_human def: "Protein FAM13B1 gene" [UniProtKB:Q9NYF5] synonym: "C5orf5" EXACT [UniProtKB:Q9NYF5] xref: EMBL:AF157316 xref: EMBL:AF251038 xref: EMBL:BC048965 xref: EMBL:BC056887 xref: EMBL:CH471062 xref: HGNC:HGNC:1335 xref: UniGene:Hs.657919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056284 ! Q3ZCR0_HUMAN relationship: codes_for CCO:B0058961 ! FA13B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021118 name: LOC100129482_human def: "LOC100129482 protein gene" [UniProtKB:Q49A40] xref: EMBL:BC045697 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056298 ! Q49A40_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021119 name: ARL7_human def: "ADP ribosylation factor-like protein 7 gene" [UniProtKB:Q4A519] xref: EMBL:AJ579850 xref: HGNC:HGNC:698 xref: UniGene:Hs.699342 xref: UniGene:Hs.705494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056309 ! Q4A519_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021120 name: MGC72080_human def: "MGC72080 protein gene" [UniProtKB:Q4G0Q6] xref: EMBL:BC029615 xref: EMBL:BC042035 xref: EMBL:BC062733 xref: UniGene:Hs.655977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016067 ! Q4G0Q6_HUMAN relationship: codes_for CCO:B0016073 ! Q6P5R4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021121 name: GPR68_human def: "Orphan GPCR 68 gene" [UniProtKB:Q4VBB4] synonym: "hCG_20030" EXACT [UniProtKB:Q4VBB4] xref: EMBL:BC096071 xref: EMBL:BC096072 xref: EMBL:BC096073 xref: EMBL:BC096074 xref: EMBL:BC098567 xref: EMBL:CH471061 xref: EMBL:EU883575 xref: HGNC:HGNC:4519 xref: UniGene:Hs.8882 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024303 ! Q4VBB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021122 name: MGC45428_human def: "Putative uncharacterized protein MGC45428 gene" [UniProtKB:Q4W5L5] xref: EMBL:AC093748 xref: HGNC:HGNC:19002 xref: UniGene:Hs.591683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030618 ! Q4W5L5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021123 name: Hosa(Biaka)-T2R2_human def: "Bitter taste receptor T2R2 gene" [UniProtKB:Q50KZ9] synonym: "Hosa(Adygei)-T2R2" EXACT [UniProtKB:Q50KZ9] xref: EMBL:AB198992 xref: EMBL:AB198994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056342 ! Q50KZ9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021124 name: HKE1.5_human def: "GDS-related protein gene" [UniProtKB:Q54AJ0] xref: EMBL:AB012295 xref: HGNC:HGNC:9769 xref: UniGene:Hs.509622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056370 ! Q54AJ0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021125 name: KIAA0194_human def: "KIAA0194 protein gene" [UniProtKB:Q562E5] xref: EMBL:BC092520 xref: UniGene:Hs.586219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056371 ! Q562E5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021126 name: DKFZp686C13142_human def: "Putative uncharacterized protein DKFZp686C13142 gene" [UniProtKB:Q5CZI3] xref: EMBL:BX647475 xref: HGNC:HGNC:15624 xref: UniGene:Hs.515215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056420 ! Q5CZI3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021127 name: DKFZp686D0345_human def: "Putative uncharacterized protein DKFZp686D0345 gene" [UniProtKB:Q5HCI0] xref: EMBL:CR627020 xref: HGNC:HGNC:949 xref: UniGene:Hs.485139 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056441 ! Q5HCI0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021128 name: DKFZp686K101_human def: "Putative uncharacterized protein DKFZp686K101 gene" [UniProtKB:Q5HYD7] xref: EMBL:BX647927 xref: HGNC:HGNC:9060 xref: UniGene:Hs.80776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056443 ! Q5HYD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021129 name: GPR24_human def: "G-protein coupled receptor 24 isoform 1 gene" [UniProtKB:Q5IFH6] xref: EMBL:AY747629 xref: HGNC:HGNC:4479 xref: UniGene:Hs.248122 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056446 ! Q5IFH6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021130 name: MEF2D/DAZAP1 fusion_human def: "Myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein gene" [UniProtKB:Q5IRN4] xref: EMBL:AY675556 xref: HGNC:HGNC:6997 xref: UniGene:Hs.314327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056447 ! Q5IRN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021131 name: DKFZp667A016_human def: "Putative uncharacterized protein DKFZp667A016 gene" [UniProtKB:Q5JPD2] xref: EMBL:AL833195 xref: HGNC:HGNC:16862 xref: UniGene:Hs.642736 xref: UniGene:Hs.706280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056452 ! Q5JPD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021132 name: DKFZp667L0117_human def: "Putative uncharacterized protein DKFZp667L0117 gene" [UniProtKB:Q5JPJ2] xref: EMBL:AL832265 xref: HGNC:HGNC:17409 xref: UniGene:Hs.631591 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056453 ! Q5JPJ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021133 name: RP13-102H20.1_human def: "Novel protein (Putative uncharacterized protein RP13-102H20.1) gene" [UniProtKB:Q5JRM1] synonym: "hCG_1981033" EXACT [UniProtKB:Q5JRM1] synonym: "RP13-102H20.1-002" EXACT [UniProtKB:Q5JRM1] xref: EMBL:AL590131 xref: EMBL:CH471107 xref: UniGene:Hs.22905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056469 ! Q5JRM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021134 name: DKFZp566E034_human def: "Putative uncharacterized protein DKFZp566E034 gene" [UniProtKB:Q5JW63] xref: EMBL:AL132665 xref: HGNC:HGNC:1085 xref: UniGene:Hs.131226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056497 ! Q5JW63_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021135 name: DKFZp564G0422_human def: "Putative uncharacterized protein DKFZp564G0422 gene" [UniProtKB:Q5JXL8] xref: EMBL:AL050386 xref: HGNC:HGNC:871 xref: UniGene:Hs.590908 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056499 ! Q5JXL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021136 name: TRMT11_human def: "tRNA methyltransferase 11 homolog (S. cerevisiae) gene" [UniProtKB:Q5JY03] synonym: "RP1-187J11.2-001" EXACT [UniProtKB:Q5JY03] xref: EMBL:AL035689 xref: HGNC:HGNC:21080 xref: UniGene:Hs.404186 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056504 ! Q5JY03_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021137 name: KPG_013_human def: "KPG_013 protein gene" [UniProtKB:Q5KU14] xref: EMBL:AB045125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056516 ! Q5KU14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021138 name: KPG_009_human def: "G-protein coupled receptor gene" [UniProtKB:Q5KU19] xref: EMBL:AB041942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056517 ! Q5KU19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021139 name: KPG_008_human def: "G-protein coupled receptor gene" [UniProtKB:Q5KU20] xref: EMBL:AB041941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056518 ! Q5KU20_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021140 name: KPG_007_human def: "G-protein coupled receptor gene" [UniProtKB:Q5KU21] xref: EMBL:AB041940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056519 ! Q5KU21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021141 name: KPG_006_human def: "G-protein coupled receptor gene" [UniProtKB:Q5KU22] xref: EMBL:AB041939 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056520 ! Q5KU22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021142 name: RBPSUHL_human def: "Recombining binding protein suppressor of hairless (Drosophila)-like (Recombining binding protein suppressor of hairless (Drosophila)-like, isoform CRA_b) gene" [UniProtKB:Q5QPV0] synonym: "hCG_38385" EXACT [UniProtKB:Q5QPV0] synonym: "RP3-453C12.2-002" EXACT [UniProtKB:Q5QPV0] xref: EMBL:AL021578 xref: EMBL:CH471077 xref: HGNC:HGNC:13761 xref: UniGene:Hs.248217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056529 ! Q5QPV0_HUMAN relationship: codes_for CCO:B0056530 ! Q5QPV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021143 name: RP11-114F7.3_human def: "Novel protein gene" [UniProtKB:Q5SVK9] synonym: "RP11-114F7.3-002" EXACT [UniProtKB:Q5SVK9] xref: EMBL:AL392107 xref: EMBL:AL627434 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056544 ! Q5SVK9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021144 name: SLIT1_human def: "Slit homolog 1 (Drosophila) gene" [UniProtKB:Q5T0V2] synonym: "RP11-175O19.2-004" EXACT [UniProtKB:Q5T0V2] xref: EMBL:AL512424 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027573 ! Q5T0V3_HUMAN relationship: codes_for CCO:B0027574 ! Q5T0V2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021145 name: NIN/PDGFRB fusion_human def: "NIN/PDGFRB fusion protein gene" [UniProtKB:Q5UBV6] xref: EMBL:AY764156 xref: UniGene:Hs.310429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056641 ! Q5UBV6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021146 name: FLT3_human def: "Tyrosine-protein kinase receptor gene" [UniProtKB:Q5VTU6] synonym: "RP11-153M24.3-001" EXACT [UniProtKB:Q5VTU6] xref: EMBL:AL356915 xref: EMBL:AL445262 xref: EMBL:AL591024 xref: HGNC:HGNC:3765 xref: UniGene:Hs.507590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056650 ! Q5VTU6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021147 name: ARHGEF10L_human def: "Rho guanine nucleotide exchange factor 10-like protein gene" [UniProtKB:Q9HCE6] synonym: "GRINCHGEF" EXACT [UniProtKB:Q9HCE6] synonym: "KIAA1626" EXACT [UniProtKB:Q9HCE6] xref: EMBL:AB046846 xref: EMBL:AK001383 xref: EMBL:AK092020 xref: EMBL:AL139250 xref: EMBL:AL358593 xref: EMBL:BC065561 xref: EMBL:BC080596 xref: EMBL:BC117171 xref: EMBL:DQ139833 xref: HGNC:HGNC:25540 xref: UniGene:Hs.443460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056666 ! Q5VXI4_HUMAN relationship: codes_for CCO:B0058804 ! ARGAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021148 name: ARHGEF2_human def: "Rho guanine nucleotide exchange factor 2 gene" [UniProtKB:Q92974] synonym: "KIAA0651" EXACT [UniProtKB:Q92974] synonym: "LFP40" EXACT [UniProtKB:Q92974] xref: EMBL:AB014551 xref: EMBL:AF486838 xref: EMBL:AL355388 xref: EMBL:AL512715 xref: EMBL:BC020567 xref: EMBL:BT007407 xref: EMBL:CH471121 xref: EMBL:U72206 xref: EMBL:X15610 xref: HGNC:HGNC:682 xref: UniGene:Hs.655209 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056669 ! Q5VY93_HUMAN relationship: codes_for CCO:B0063053 ! ARHG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021149 name: DCAMKL1_human def: "Doublecortin and CaM kinase-like 1 gene" [UniProtKB:Q5VZY9] synonym: "RP11-113P14.1-001" EXACT [UniProtKB:Q5VZY9] xref: EMBL:AL157694 xref: EMBL:AL157760 xref: EMBL:AL160392 xref: EMBL:AL390029 xref: HGNC:HGNC:2700 xref: UniGene:Hs.507755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030607 ! Q5VZY9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021150 name: KIAA0142_human def: "KIAA0142 splice variant 1 gene" [UniProtKB:Q5W9H1] xref: EMBL:AB177848 xref: HGNC:HGNC:15607 xref: UniGene:Hs.508738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056681 ! Q5W9H1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021151 name: AngA_human def: "Angiopoietin-A gene" [UniProtKB:Q5YLW1] xref: EMBL:AY055342 xref: HGNC:HGNC:484 xref: UniGene:Hs.369675 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056684 ! Q5YLW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021152 name: DKFZp686J1732_human def: "Putative uncharacterized protein DKFZp686J1732 gene" [UniProtKB:Q63HN4] xref: EMBL:BX648093 xref: HGNC:HGNC:23239 xref: UniGene:Hs.440553 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056689 ! Q63HN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021153 name: DKFZp666D035_human def: "Putative uncharacterized protein DKFZp666D035 gene" [UniProtKB:Q658N8] synonym: "hCG_1994295" EXACT [UniProtKB:Q658N8] synonym: "ZNF195" EXACT [UniProtKB:Q658N8] xref: EMBL:AL833722 xref: EMBL:BC121028 xref: EMBL:CH471158 xref: HGNC:HGNC:12986 xref: UniGene:Hs.386294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056692 ! Q658N8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021154 name: DKFZp666O0110_human def: "Putative uncharacterized protein DKFZp666O0110 gene" [UniProtKB:Q658W2] xref: EMBL:AL832961 xref: HGNC:HGNC:9611 xref: UniGene:Hs.395482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056693 ! Q658W2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021155 name: DKFZp666M0710_human def: "Putative uncharacterized protein DKFZp666M0710 gene" [UniProtKB:Q658W4] xref: EMBL:AL832959 xref: HGNC:HGNC:17849 xref: UniGene:Hs.274136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056694 ! Q658W4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021156 name: DKFZp686A1965_human def: "Putative uncharacterized protein DKFZp686A1965 gene" [UniProtKB:Q68CU0] xref: EMBL:CR749782 xref: HGNC:HGNC:13146 xref: UniGene:Hs.513292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056699 ! Q68CU0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021157 name: DKFZp686D1580_human def: "Putative uncharacterized protein DKFZp686D1580 gene" [UniProtKB:Q68CY8] xref: EMBL:CR749648 xref: HGNC:HGNC:7965 xref: UniGene:Hs.432976 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056700 ! Q68CY8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021158 name: DKFZp686J099_human def: "Putative uncharacterized protein DKFZp686J099 gene" [UniProtKB:Q68D02] xref: EMBL:CR749634 xref: UniGene:Hs.481545 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056701 ! Q68D02_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021159 name: DKFZp781B1032_human def: "Putative uncharacterized protein DKFZp781B1032 gene" [UniProtKB:Q68DD1] xref: EMBL:CR749452 xref: UniGene:Hs.440898 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0020119 ! Q68DD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021160 name: DKFZp779B0247_human def: "Putative uncharacterized protein DKFZp779B0247 gene" [UniProtKB:Q68DF1] xref: EMBL:CR749431 xref: HGNC:HGNC:29905 xref: UniGene:Hs.705404 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056703 ! Q68DF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021161 name: DKFZp686M13211_human def: "Putative uncharacterized protein DKFZp686M13211 gene" [UniProtKB:Q68DL5] xref: EMBL:CR749352 xref: HGNC:HGNC:2895 xref: UniGene:Hs.171971 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056704 ! Q68DL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021162 name: DKFZp686H10254_human def: "Putative uncharacterized protein DKFZp686H10254 gene" [UniProtKB:Q68DR4] xref: EMBL:CR749301 xref: HGNC:HGNC:13104 xref: UniGene:Hs.632294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056705 ! Q68DR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021163 name: DKFZp686L0365_human def: "Putative uncharacterized protein DKFZp686L0365 gene" [UniProtKB:Q68DZ5] xref: EMBL:AK297059 xref: EMBL:CR749218 xref: HGNC:HGNC:712 xref: UniGene:Hs.435811 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056706 ! Q68DZ5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021164 name: DKFZp686N1969_human def: "Putative uncharacterized protein DKFZp686N1969 gene" [UniProtKB:Q68E09] xref: EMBL:CR749203 xref: HGNC:HGNC:13209 xref: UniGene:Hs.334 xref: UniGene:Hs.534621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056707 ! Q68E09_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021165 name: DKFZp686G16234_human def: "Putative uncharacterized protein DKFZp686G16234 gene" [UniProtKB:Q68E11] xref: EMBL:CR749201 xref: HGNC:HGNC:8972 xref: UniGene:Hs.497487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056708 ! Q68E11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021166 name: DKFZp781L0674_human def: "Putative uncharacterized protein DKFZp781L0674 gene" [UniProtKB:Q6AI30] xref: EMBL:CR627389 xref: HGNC:HGNC:3490 xref: UniGene:Hs.22634 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056716 ! Q6AI30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021167 name: DKFZp779O0162_human def: "Putative uncharacterized protein DKFZp779O0162 gene" [UniProtKB:Q6AW80] xref: EMBL:BX649089 xref: HGNC:HGNC:7982 xref: UniGene:Hs.279522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056717 ! Q6AW80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021168 name: LOC554248_human def: "LOC554248 protein gene" [UniProtKB:Q6DCA4] xref: EMBL:BC078169 xref: UniGene:Hs.699798 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056721 ! Q6DCA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021169 name: C12orf2_human def: "C12orf2 protein gene" [UniProtKB:Q6IB99] xref: EMBL:CR456905 xref: HGNC:HGNC:13232 xref: UniGene:Hs.696433 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056758 ! Q6IB99_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021170 name: OR10S1_human def: "Olfactory receptor OR11-279 (Olfactory receptor, family 10, subfamily S, member 1) gene" [UniProtKB:Q6IEV3] xref: EMBL:BC137038 xref: EMBL:BK004509 xref: HGNC:HGNC:14807 xref: UniGene:Hs.553637 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056763 ! Q6IEV3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021171 name: hCG_2044305_human def: "Olfactory receptor OR7-15 (HCG2044305) gene" [UniProtKB:Q6IF40] xref: EMBL:BK004422 xref: EMBL:CH878732 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056777 ! Q6IF40_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021172 name: OR13C3_human def: "Olfactory receptor OR9-8 (Olfactory receptor, family 13, subfamily C, member 3) gene" [UniProtKB:Q6IF52] xref: EMBL:BC136949 xref: EMBL:BC136952 xref: EMBL:BK004410 xref: HGNC:HGNC:14704 xref: UniGene:Hs.553600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056779 ! Q6IF52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021173 name: hCG_2044349_human def: "Olfactory receptor OR11-140 (HCG2044349) gene" [UniProtKB:Q6IFD1] xref: EMBL:BK004331 xref: EMBL:CH471076 xref: HGNC:HGNC:8336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056786 ! Q6IFD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021174 name: OR1S1_human def: "Olfactory receptor OR11-232 (Olfactory receptor, family 1, subfamily S, member 1) gene" [UniProtKB:Q6IFG3] synonym: "hCG_2044354" EXACT [UniProtKB:Q6IFG3] xref: EMBL:BK004299 xref: EMBL:CH471076 xref: HGNC:HGNC:8227 xref: UniGene:Hs.553645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056790 ! Q6IFG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021175 name: OR51F2_human def: "Olfactory receptor OR11-23 (Olfactory receptor, family 51, subfamily F, member 2) gene" [UniProtKB:Q6IFI1] synonym: "hCG_1646469" EXACT [UniProtKB:Q6IFI1] xref: EMBL:BC136877 xref: EMBL:BK004281 xref: EMBL:CH471064 xref: HGNC:HGNC:15197 xref: UniGene:Hs.553562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056797 ! Q6IFI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021176 name: OR13D1_human def: "Olfactory receptor OR9-15 (Olfactory receptor, family 13, subfamily D, member 1) gene" [UniProtKB:Q6IFL1] synonym: "RP11-413C10.1-001" EXACT [UniProtKB:Q6IFL1] xref: EMBL:AL359846 xref: EMBL:BK004251 xref: HGNC:HGNC:14695 xref: UniGene:Hs.553683 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056807 ! Q6IFL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021177 name: OR3A3_human def: "Olfactory receptor OR17-22 (Olfactory receptor, family 3, subfamily A, member 3) gene" [UniProtKB:Q6IFM6] xref: EMBL:BC069415 xref: EMBL:BK004236 xref: HGNC:HGNC:8284 xref: UniGene:Hs.532689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056809 ! Q6IFM6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021178 name: CIB3_human def: "CIB3 protein gene" [UniProtKB:Q6ISP1] synonym: "hCG_1776192" EXACT [UniProtKB:Q6ISP1] xref: EMBL:BC069428 xref: EMBL:CH471106 xref: HGNC:HGNC:24580 xref: UniGene:Hs.255432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056829 ! Q6ISP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021179 name: TIRAP3_human def: "Toll-like receptor adapter molecule 2 (TICAM-2) (Putative NF-kappa-B- activating protein 502). gene" [UniProtKB:Q6JUT2] synonym: "hCG_37564" EXACT [UniProtKB:Q6JUT2] xref: EMBL:AY304581 xref: EMBL:AY304584 xref: EMBL:CH471086 xref: HGNC:HGNC:21354 xref: UniGene:Hs.705455 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056831 ! Q6JUT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021180 name: C20orf157_human def: "Uncharacterized protein C20orf157. gene" [UniProtKB:Q6KAL7] synonym: "RP5-981L23.6-001" EXACT [UniProtKB:Q6KAL7] xref: EMBL:AL031686 xref: HGNC:HGNC:16150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056832 ! Q6KAL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021181 name: DKFZp686J07132_human def: "Putative uncharacterized protein DKFZp686J07132 gene" [UniProtKB:Q6MZH2] xref: EMBL:BX641138 xref: HGNC:HGNC:9770 xref: UniGene:Hs.40758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056840 ! Q6MZH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021182 name: DKFZp686I1383_human def: "Putative uncharacterized protein DKFZp686I1383 gene" [UniProtKB:Q6MZK5] xref: EMBL:BX641043 xref: HGNC:HGNC:10521 xref: UniGene:Hs.32721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056841 ! Q6MZK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021183 name: DKFZp686N23123_human def: "Putative uncharacterized protein DKFZp686N23123 gene" [UniProtKB:Q6MZQ9] xref: EMBL:BX640939 xref: HGNC:HGNC:3467 xref: UniGene:Hs.208124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030143 ! Q6MZQ9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021184 name: DKFZp686G19178_human def: "Putative uncharacterized protein DKFZp686G19178 gene" [UniProtKB:Q6MZR9] synonym: "hCG_27036" EXACT [UniProtKB:Q6MZR9] synonym: "TEAD4" EXACT [UniProtKB:Q6MZR9] xref: EMBL:BX640921 xref: EMBL:CH471116 xref: HGNC:HGNC:11717 xref: UniGene:Hs.94865 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032269 ! Q6MZR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021185 name: DKFZp686D1354_human def: "Putative uncharacterized protein DKFZp686D1354 gene" [UniProtKB:Q6MZT2] xref: EMBL:BX640899 xref: HGNC:HGNC:2731 xref: UniGene:Hs.591469 xref: UniGene:Hs.593833 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056843 ! Q6MZT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021186 name: DKFZp686C24207_human def: "Putative uncharacterized protein DKFZp686C24207 gene" [UniProtKB:Q6N011] xref: EMBL:BX640755 xref: HGNC:HGNC:6199 xref: UniGene:Hs.535903 xref: UniGene:Hs.683465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056844 ! Q6N011_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021187 name: DKFZp686O17118_human def: "Putative uncharacterized protein DKFZp686O17118 gene" [UniProtKB:Q6N016] xref: EMBL:BX640749 xref: HGNC:HGNC:12902 xref: UniGene:Hs.431471 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056845 ! Q6N016_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021188 name: DKFZp686D0662_human def: "Putative uncharacterized protein DKFZp686D0662 gene" [UniProtKB:Q6N087] xref: EMBL:BX640634 xref: HGNC:HGNC:3488 xref: UniGene:Hs.369438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030317 ! Q6N087_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021189 name: DKFZp686I13174_human def: "Putative uncharacterized protein DKFZp686I13174 gene" [UniProtKB:Q6N0A5] xref: EMBL:BX640609 xref: HGNC:HGNC:4044 xref: UniGene:Hs.591863 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056849 ! Q6N0A5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021190 name: BARX2_human def: "BARX homeobox 2 gene" [UniProtKB:Q6NT51] synonym: "hCG_38603" EXACT [UniProtKB:Q6NT51] xref: EMBL:BC069378 xref: EMBL:BC111432 xref: EMBL:BC111572 xref: EMBL:CH471065 xref: HGNC:HGNC:956 xref: UniGene:Hs.591944 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056857 ! Q6NT51_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021191 name: LOC100134868_human def: "LOC100134868 protein gene" [UniProtKB:Q6P6B2] xref: EMBL:BC030737 xref: EMBL:BC062357 xref: UniGene:Hs.516956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056893 ! Q6P6B2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021192 name: TBC1D3P2_human def: "TBC1D3P2 protein gene" [UniProtKB:Q6PD72] xref: EMBL:BC058890 xref: HGNC:HGNC:27783 xref: UniGene:Hs.448884 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056900 ! Q6PD72_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021193 name: MGC4836_human def: "MGC4836 protein gene" [UniProtKB:Q6PID2] xref: EMBL:BC036758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056911 ! Q6PID2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021194 name: LOC441453_human def: "LOC441453 protein gene" [UniProtKB:Q6PK25] xref: EMBL:BC008657 xref: UniGene:Hs.523504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056923 ! Q6PK25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021195 name: DUX4c_human def: "Double homeobox 4c gene" [UniProtKB:Q6RFH8] xref: EMBL:AY500824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056935 ! Q6RFH8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021196 name: UNQ9373_human def: "VNFT9373 gene" [UniProtKB:Q6UXT6] xref: EMBL:AY358215 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056954 ! Q6UXT6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021197 name: POLQ_human def: "DNA polymerase theta gene" [UniProtKB:Q6VMB5] xref: EMBL:AY032677 xref: EMBL:AY338826 xref: HGNC:HGNC:9186 xref: UniGene:Hs.241517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056961 ! Q6VMB5_HUMAN relationship: codes_for CCO:B0058391 ! Q96SE4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021198 name: CINCIN1_human def: "CINCIN1 gene" [UniProtKB:Q6XZE5] xref: EMBL:AY196783 xref: HGNC:HGNC:16394 xref: UniGene:Hs.200242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056973 ! Q6XZE5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021199 name: FLJ00420_human def: "FLJ00420 protein gene" [UniProtKB:Q6ZMJ6] xref: EMBL:AK160386 xref: HGNC:HGNC:7879 xref: UniGene:Hs.343571 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056977 ! Q6ZMJ6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021200 name: NPIP_human def: "FLJ00322 protein gene" [UniProtKB:Q6ZMK5] synonym: "FLJ00322" EXACT [UniProtKB:Q6ZMK5] xref: EMBL:AK160377 xref: HGNC:HGNC:7909 xref: UniGene:Hs.694739 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056978 ! Q6ZMK5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021201 name: FLJ00320_human def: "FLJ00320 protein gene" [UniProtKB:Q6ZMK6] xref: EMBL:AK160376 xref: HGNC:HGNC:21037 xref: UniGene:Hs.235390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056979 ! Q6ZMK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021202 name: FLJ00312_human def: "FLJ00312 protein gene" [UniProtKB:Q6ZMK7] xref: EMBL:AK160375 xref: HGNC:HGNC:23463 xref: UniGene:Hs.314437 xref: UniGene:Hs.645346 xref: UniGene:Hs.647203 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056980 ! Q6ZMK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021203 name: FLJ00301_human def: "FLJ00301 protein gene" [UniProtKB:Q6ZML0] xref: EMBL:AK160372 xref: HGNC:HGNC:30487 xref: UniGene:Hs.579576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056981 ! Q6ZML0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021204 name: FLJ00288_human def: "FLJ00288 protein gene" [UniProtKB:Q6ZNK8] xref: EMBL:AK131086 xref: HGNC:HGNC:23609 xref: UniGene:Hs.655273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057027 ! Q6ZNK8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021205 name: P2Y2-like_human def: "Nucleoside/nucleotide receptor gene" [UniProtKB:Q711G2] xref: EMBL:AJ345013 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057094 ! Q711G2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021206 name: htr4_human def: "Serotonin receptor 5-HT4 gene" [UniProtKB:Q712M9] xref: EMBL:AJ131726 xref: HGNC:HGNC:5299 xref: UniGene:Hs.483773 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057095 ! Q712M9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021207 name: VIP2R_human def: "Vasoactive intestinal polypeptide receptor 2 gene" [UniProtKB:Q71V81] xref: EMBL:AF027390 xref: HGNC:HGNC:12695 xref: UniGene:Hs.654505 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057100 ! Q71V81_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021208 name: MGC12518_human def: "Putative uncharacterized protein MGC12518 gene" [UniProtKB:Q75LP1] xref: EMBL:AC092161 xref: HGNC:HGNC:13067 xref: UniGene:Hs.520889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032368 ! Q75LP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021209 name: ZNF534_human def: "Zinc finger protein 534. gene" [UniProtKB:Q76KX8] xref: EMBL:AB086840 xref: HGNC:HGNC:26337 xref: UniGene:Hs.447583 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057104 ! Q76KX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021210 name: GPCR_human def: "Putative G-protein coupled receptor gene" [UniProtKB:Q76L88] xref: EMBL:AB083591 xref: EMBL:AB083612 xref: EMBL:AB083618 xref: EMBL:AB083622 xref: HGNC:HGNC:18990 xref: HGNC:HGNC:23626 xref: UniGene:Hs.256897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057106 ! Q76L88_HUMAN relationship: codes_for CCO:B0057936 ! Q8TDT4_HUMAN relationship: codes_for CCO:B0057937 ! Q8TDT9_HUMAN relationship: codes_for CCO:B0057942 ! Q8TDV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021211 name: TITF1_human def: "Thyroid transcription factor 1 gene" [UniProtKB:Q7KZF6] synonym: "hCG_20987" EXACT [UniProtKB:Q7KZF6] xref: EMBL:BT009773 xref: EMBL:CH471078 xref: HGNC:HGNC:11825 xref: UniGene:Hs.705388 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032530 ! Q7KZF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021212 name: LIMK2_human def: "LIM domain kinase 2 (LIM domain kinase 2, isoform CRA_b) gene" [UniProtKB:Q7L3H5] synonym: "hCG_2010534" EXACT [UniProtKB:Q7L3H5] xref: EMBL:BC013051 xref: EMBL:CH471095 xref: HGNC:HGNC:6614 xref: UniGene:Hs.474596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057117 ! Q7L3H5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021213 name: DKFZp686A24188_human def: "Putative uncharacterized protein DKFZp686A24188 gene" [UniProtKB:Q7Z2I8] synonym: "DKFZp686B23188" EXACT [UniProtKB:Q7Z2I8] xref: EMBL:BX537617 xref: EMBL:BX538179 xref: HGNC:HGNC:11905 xref: UniGene:Hs.521456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057142 ! Q7Z2I8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021214 name: tgat_human def: "Transforming gene product TGAT gene" [UniProtKB:Q7Z2K2] xref: EMBL:AB115332 xref: HGNC:HGNC:12303 xref: UniGene:Hs.130031 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057143 ! Q7Z2K2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021215 name: DKFZp686K1352_human def: "Putative uncharacterized protein DKFZp686K1352 gene" [UniProtKB:Q7Z3D9] xref: EMBL:BX537967 xref: HGNC:HGNC:11623 xref: UniGene:Hs.511504 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057147 ! Q7Z3D9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021216 name: DKFZp686N1286_human def: "Putative uncharacterized protein DKFZp686N1286 gene" [UniProtKB:Q7Z3E4] synonym: "TRDMT1" EXACT [UniProtKB:Q7Z3E4] xref: EMBL:BX537961 xref: EMBL:EF444974 xref: HGNC:HGNC:2977 xref: UniGene:Hs.351665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057148 ! Q7Z3E4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021217 name: DKFZp686I05275_human def: "Nuclear factor 1 gene" [UniProtKB:Q7Z3K7] xref: EMBL:BX537794 xref: HGNC:HGNC:7788 xref: UniGene:Hs.257970 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025409 ! Q7Z3K7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021218 name: DKFZp686J1593_human def: "Putative uncharacterized protein DKFZp686J1593 gene" [UniProtKB:Q7Z3R3] xref: EMBL:BX537502 xref: UniGene:Hs.32721 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057153 ! Q7Z3R3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021219 name: MST090_human def: "MSTP090 gene" [UniProtKB:Q7Z4E8] xref: EMBL:AF172819 xref: HGNC:HGNC:13375 xref: UniGene:Hs.523702 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057163 ! Q7Z4E8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021220 name: usf1-bd_human def: "Upstream stimulatory factor 1 BD gene" [UniProtKB:Q7Z5Y1] xref: EMBL:AB098540 xref: HGNC:HGNC:12593 xref: UniGene:Hs.414880 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057187 ! Q7Z5Y1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021221 name: DKFZp779N0926_human def: "Putative uncharacterized protein DKFZp779N0926 gene" [UniProtKB:Q7Z664] xref: EMBL:BX538098 xref: HGNC:HGNC:3694 xref: UniGene:Hs.546255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057191 ! Q7Z664_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021222 name: DKFZp779E2460_human def: "Putative uncharacterized protein DKFZp779E2460 gene" [UniProtKB:Q7Z670] xref: EMBL:BX537853 xref: HGNC:HGNC:17186 xref: UniGene:Hs.352183 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057192 ! Q7Z670_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021223 name: DKFZp779A1451_human def: "Putative uncharacterized protein DKFZp779A1451 gene" [UniProtKB:Q7Z679] xref: EMBL:BX537778 xref: HGNC:HGNC:11594 xref: UniGene:Hs.146196 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057193 ! Q7Z679_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021224 name: ZNF850P_human def: "ZNF850P protein gene" [UniProtKB:Q7Z7K7] xref: EMBL:BC052603 xref: UniGene:Hs.406307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057216 ! Q7Z7K7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021225 name: LOC100128510_human def: "LOC100128510 protein gene" [UniProtKB:Q86V93] synonym: "hCG_1818572" EXACT [UniProtKB:Q86V93] synonym: "ZNF75A" EXACT [UniProtKB:Q86V93] xref: EMBL:BC051366 xref: EMBL:CH471112 xref: UniGene:Hs.513292 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021159 ! Q86V93_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021226 name: VHLAK_human def: "PVHL-associated KRAB domain-containing protein gene" [UniProtKB:Q86VG0] xref: EMBL:AY074878 xref: HGNC:HGNC:12988 xref: UniGene:Hs.157035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021155 ! Q86VG0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021227 name: ZNF26_human def: "Zinc finger protein 26 gene" [UniProtKB:Q86X57] synonym: "hCG_1810866" EXACT [UniProtKB:Q86X57] xref: EMBL:BC046206 xref: EMBL:CH471218 xref: HGNC:HGNC:13053 xref: UniGene:Hs.489608 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057285 ! Q86X57_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021228 name: JRK_human def: "JRK protein (Jerky homolog (Mouse), isoform CRA_a) gene" [UniProtKB:Q86XJ5] synonym: "hCG_1641521" EXACT [UniProtKB:Q86XJ5] xref: EMBL:BC043351 xref: EMBL:CH471162 xref: HGNC:HGNC:6199 xref: UniGene:Hs.535903 xref: UniGene:Hs.683465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057289 ! Q86XJ5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021229 name: FLJ00332_human def: "FLJ00332 protein gene" [UniProtKB:Q86YV2] xref: EMBL:AK122585 xref: HGNC:HGNC:24702 xref: UniGene:Hs.534648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057313 ! Q86YV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021230 name: OR11H13P_human def: "Seven transmembrane helix receptor gene" [UniProtKB:Q8IXE0] xref: EMBL:AB065941 xref: HGNC:HGNC:29997 xref: UniGene:Hs.554706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057371 ! Q8IXE0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021231 name: DKFZp547B0614_human def: "Putative uncharacterized protein DKFZp547B0614 gene" [UniProtKB:Q8NDC7] xref: EMBL:AL834279 xref: HGNC:HGNC:700 xref: UniGene:Hs.632446 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057576 ! Q8NDC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021232 name: DKFZp547H1810_human def: "Microtubule-associated protein gene" [UniProtKB:Q8NDS5] xref: EMBL:AL831878 xref: HGNC:HGNC:6862 xref: UniGene:Hs.517949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057579 ! Q8NDS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021233 name: TMEPAI_human def: "PMEPA1 variant A protein gene" [UniProtKB:Q8NER4] synonym: "hCG_40101" EXACT [UniProtKB:Q8NER4] synonym: "RP4-718J7.3-006" EXACT [UniProtKB:Q8NER4] xref: EMBL:AL035541 xref: EMBL:AL121913 xref: EMBL:AY128643 xref: EMBL:CH471077 xref: HGNC:HGNC:14107 xref: UniGene:Hs.517155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057594 ! Q8NER4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021234 name: BAK_human def: "Pro-apoptotic protein BAKM variant gene" [UniProtKB:Q8NFF3] xref: EMBL:AF520590 xref: HGNC:HGNC:949 xref: UniGene:Hs.485139 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057601 ! Q8NFF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021235 name: OR5E1P_human def: "Seven transmembrane helix receptor (HCG1641819) gene" [UniProtKB:Q8NGM3] synonym: "hCG_1641819" EXACT [UniProtKB:Q8NGM3] xref: EMBL:AB065769 xref: EMBL:CH471064 xref: HGNC:HGNC:8342 xref: UniGene:Hs.382973 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057713 ! Q8NGM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021236 name: OR52B2_human def: "Seven transmembrane helix receptor (Olfactory receptor, family 52, subfamily B, member 2) (Olfactory receptor OR11-70) gene" [UniProtKB:Q8NGM7] synonym: "hCG_1810925" EXACT [UniProtKB:Q8NGM7] xref: EMBL:AB065763 xref: EMBL:BC136732 xref: EMBL:BC136733 xref: EMBL:BK004324 xref: EMBL:CH471064 xref: HGNC:HGNC:15207 xref: UniGene:Hs.690457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057717 ! Q8NGM7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021237 name: OR2J4P_human def: "Seven transmembrane helix receptor gene" [UniProtKB:Q8NGU6] xref: EMBL:AB065683 xref: HGNC:HGNC:8262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057763 ! Q8NGU6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021238 name: DRD5P1_human def: "Seven transmembrane helix receptor gene" [UniProtKB:Q8NGW2] xref: EMBL:AB065661 xref: HGNC:HGNC:3027 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057770 ! Q8NGW2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021239 name: OR10R3P_human def: "Seven transmembrane helix receptor gene" [UniProtKB:Q8NGX7] xref: EMBL:AB065639 xref: HGNC:HGNC:14829 xref: UniGene:Hs.640254 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057778 ! Q8NGX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021240 name: hCG_39951_human def: "Seven transmembrane helix receptor (HCG39951) gene" [UniProtKB:Q8NGY4] xref: EMBL:AB065632 xref: EMBL:CH471121 xref: HGNC:HGNC:15030 xref: UniGene:Hs.554488 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057784 ! Q8NGY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021241 name: DRD5P2_human def: "Seven transmembrane helix receptor gene" [UniProtKB:Q8NH22] xref: EMBL:AB065590 xref: HGNC:HGNC:3028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057812 ! Q8NH22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021242 name: hCG_2044188_human def: "Seven transmembrane helix receptor (HCG2044188) gene" [UniProtKB:Q8NH77] xref: EMBL:AB065512 xref: EMBL:CH471064 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057848 ! Q8NH77_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021243 name: MGC12965_human def: "Similar to Cytochrome c, somatic gene" [UniProtKB:Q8TB74] xref: EMBL:BC019340 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057900 ! Q8TB74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021244 name: PR_human def: "Delta 4 progesterone receptor gene" [UniProtKB:Q8TDS3] synonym: "hCG_39657" EXACT [UniProtKB:Q8TDS3] synonym: "PGR" EXACT [UniProtKB:Q8TDS3] xref: EMBL:AB084248 xref: EMBL:CH471065 xref: HGNC:HGNC:8910 xref: UniGene:Hs.368072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057931 ! Q8TDS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021245 name: FLJ00153_human def: "FLJ00153 protein gene" [UniProtKB:Q8TEP0] xref: EMBL:AK074082 xref: HGNC:HGNC:3416 xref: UniGene:Hs.631624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016368 ! Q8TEP0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021246 name: CASPR4_human def: "Cell recognition protein CASPR4 gene" [UniProtKB:Q8WX98] xref: EMBL:AF463518 xref: HGNC:HGNC:18747 xref: UniGene:Hs.461389 xref: UniGene:Hs.648758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058012 ! Q8WX98_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021247 name: wisp3 varinat_human def: "WNT1 inducible signaling pathway protein 3 variant gene" [UniProtKB:Q8WYK7] xref: EMBL:AB075040 xref: HGNC:HGNC:12771 xref: UniGene:Hs.558428 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058044 ! Q8WYK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021248 name: HP8_human def: "HP8 peptide gene" [UniProtKB:Q92657] xref: EMBL:X87248 xref: HGNC:HGNC:1833 xref: UniGene:Hs.699463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058078 ! Q92657_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021249 name: K-ras_human def: "K-ras protein gene" [UniProtKB:Q92668] xref: EMBL:M26261 xref: HGNC:HGNC:5173 xref: UniGene:Hs.37003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058080 ! Q92668_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021250 name: hA2aR_human def: "Adenosine receptor subtype A2a gene" [UniProtKB:Q93003] xref: EMBL:U20232 xref: EMBL:U20233 xref: HGNC:HGNC:263 xref: UniGene:Hs.197029 xref: UniGene:Hs.700816 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058119 ! Q93003_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021251 name: TEAD4_human def: "TEA domain family member 4 gene" [UniProtKB:Q96BK2] xref: EMBL:BC015497 xref: HGNC:HGNC:11717 xref: UniGene:Hs.94865 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032264 ! Q96BK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021252 name: KIAA1829_human def: "KIAA1829 protein gene" [UniProtKB:Q96JJ8] xref: EMBL:AB058732 xref: HGNC:HGNC:29385 xref: UniGene:Hs.590940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058241 ! Q96JJ8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021253 name: PDE1B2_human def: "3'5' cyclic nucleotide phosphodiesterase 1B2 gene" [UniProtKB:Q96KP3] synonym: "hCG_21934" EXACT [UniProtKB:Q96KP3] synonym: "PDE1B" EXACT [UniProtKB:Q96KP3] xref: EMBL:AJ401609 xref: EMBL:AK302931 xref: EMBL:CH471054 xref: HGNC:HGNC:8775 xref: UniGene:Hs.530871 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058262 ! Q96KP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021254 name: ZNF390_human def: "DJ29K1.3.1 (Novel C2H2 type zinc finger protein (Isoform 1)) gene" [UniProtKB:Q96KW0] synonym: "dJ29K1.3" EXACT [UniProtKB:Q96KW0] xref: EMBL:Z98745 xref: HGNC:HGNC:21193 xref: UniGene:Hs.376873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058263 ! Q96KW0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021255 name: BGR_human def: "Beta-glucan receptor isoform H gene" [UniProtKB:Q96PA4] synonym: "CLEC7A" EXACT [UniProtKB:Q96PA4] synonym: "hCG_1773845" EXACT [UniProtKB:Q96PA4] xref: EMBL:AF400602 xref: EMBL:CH471094 xref: HGNC:HGNC:14558 xref: UniGene:Hs.143929 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058327 ! Q96PA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021256 name: FKSG74_human def: "FKSG74 gene" [UniProtKB:Q9BWW0] synonym: "hCG_1809452" EXACT [UniProtKB:Q9BWW0] xref: EMBL:AY026352 xref: EMBL:CH471357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058538 ! Q9BWW0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021257 name: FKSG73_human def: "FKSG73 (FKSG73 protein, isoform CRA_a) gene" [UniProtKB:Q9BWW1] synonym: "hCG_1983232" EXACT [UniProtKB:Q9BWW1] synonym: "LOC440888" EXACT [UniProtKB:Q9BWW1] xref: EMBL:AY026351 xref: EMBL:CH471366 xref: UniGene:Hs.534994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058539 ! Q9BWW1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021258 name: FKSG72_human def: "FKSG72 gene" [UniProtKB:Q9BWW2] xref: EMBL:AY026350 xref: UniGene:Hs.631664 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058540 ! Q9BWW2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021259 name: FKSG83_human def: "FKSG83 gene" [UniProtKB:Q9BX81] xref: EMBL:AF352327 xref: UniGene:Hs.326753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058545 ! Q9BX81_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021260 name: Fe65L2_human def: "Fe65L2 isoform 214 (I-214) gene" [UniProtKB:Q9BYD4] xref: EMBL:AB049618 xref: HGNC:HGNC:20708 xref: UniGene:Hs.529449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058575 ! Q9BYD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021261 name: FKSG41_human def: "FKSG41 gene" [UniProtKB:Q9BZ77] xref: EMBL:AF333762 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058591 ! Q9BZ77_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021262 name: FKSG35_human def: "FKSG35 gene" [UniProtKB:Q9BZC5] xref: EMBL:AF327904 xref: HGNC:HGNC:8234 xref: UniGene:Hs.490448 xref: UniGene:Hs.658609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058594 ! Q9BZC5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021263 name: FUS/ATF-1_human def: "FUS/ATF-1 protein gene" [UniProtKB:Q9H4A8] xref: EMBL:AJ295163 xref: HGNC:HGNC:783 xref: UniGene:Hs.648565 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058714 ! Q9H4A8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021264 name: FLJ00110_human def: "FLJ00110 protein gene" [UniProtKB:Q9H7H9] xref: EMBL:AK024501 xref: HGNC:HGNC:13906 xref: UniGene:Hs.655020 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015397 ! Q9H7H9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021265 name: FLJ00094_human def: "FLJ00094 protein gene" [UniProtKB:Q9H7I9] xref: EMBL:AK024491 xref: HGNC:HGNC:11203 xref: UniGene:Hs.243678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058740 ! Q9H7I9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021266 name: FLJ00050_human def: "FLJ00050 protein gene" [UniProtKB:Q9H7M0] xref: EMBL:AK024458 xref: UniGene:Hs.193857 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058741 ! Q9H7M0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021267 name: FLJ00015_human def: "FLJ00015 protein gene" [UniProtKB:Q9H7Q2] xref: EMBL:AK024426 xref: HGNC:HGNC:3337 xref: UniGene:Hs.531619 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058743 ! Q9H7Q2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021268 name: HSPDE10A_human def: "Phosphodiesterase 10A1 (PDE10A1) gene" [UniProtKB:Q9HCP9] xref: EMBL:AB041798 xref: HGNC:HGNC:8772 xref: UniGene:Hs.584856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058816 ! Q9HCP9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021269 name: dJ1186N24.3_human def: "DJ1186N24.3 (Novel zinc finger protein) gene" [UniProtKB:Q9HCY4] xref: EMBL:AL049543 xref: HGNC:HGNC:13851 xref: UniGene:Hs.176980 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058821 ! Q9HCY4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021270 name: OR51A1P_human def: "Olfactory receptor gene" [UniProtKB:Q9NSC9] synonym: "HPFH6OR" EXACT [UniProtKB:Q9NSC9] xref: EMBL:X81445 xref: HGNC:HGNC:8316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058916 ! Q9NSC9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021271 name: DKFZp434B1272_human def: "Putative uncharacterized protein DKFZp434B1272 gene" [UniProtKB:Q9NSM3] xref: EMBL:AL162032 xref: HGNC:HGNC:19893 xref: UniGene:Hs.656754 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058922 ! Q9NSM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021272 name: SCL_human def: "SCL protein gene" [UniProtKB:Q9NY94] xref: EMBL:AJ131016 xref: HGNC:HGNC:11556 xref: UniGene:Hs.525198 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058959 ! Q9NY94_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021273 name: KIAA1493_human def: "KIAA1493 protein gene" [UniProtKB:Q9P235] xref: EMBL:AB040926 xref: UniGene:Hs.530438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018931 ! Q9P235_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021274 name: ZNF72_human def: "Zinc finger protein 72 (Krueppel-related zinc finger protein). gene" [UniProtKB:Q9UC05] synonym: "hZNF1" EXACT [UniProtKB:Q9UC05] xref: EMBL:X60078 xref: HGNC:HGNC:13142 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059093 ! Q9UC05_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021275 name: estrogen receptor_human def: "Estrogen receptor protein (Estrogen receptor 1) gene" [UniProtKB:Q9UE35] synonym: "ESR1" EXACT [UniProtKB:Q9UE35] synonym: "RP1-130E4.1-007" EXACT [UniProtKB:Q9UE35] xref: EMBL:AL356311 xref: EMBL:X62462 xref: HGNC:HGNC:3467 xref: UniGene:Hs.208124 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030142 ! Q9UE35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021276 name: DKFZp586M0622_human def: "Putative uncharacterized protein DKFZp586M0622 (SMAD, mothers against DPP homolog 1 (Drosophila), isoform CRA_b) gene" [UniProtKB:Q9UFT8] synonym: "hCG_37398" EXACT [UniProtKB:Q9UFT8] synonym: "SMAD1" EXACT [UniProtKB:Q9UFT8] xref: EMBL:AL117396 xref: EMBL:CH471056 xref: HGNC:HGNC:6767 xref: UniGene:Hs.656534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059115 ! Q9UFT8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021277 name: DKFZp434N101_human def: "Putative uncharacterized protein DKFZp434N101 gene" [UniProtKB:Q9UFY1] xref: EMBL:AL110247 xref: HGNC:HGNC:9065 xref: UniGene:Hs.268177 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059118 ! Q9UFY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021278 name: DKFZp586M1622_human def: "Putative uncharacterized protein DKFZp586M1622 gene" [UniProtKB:Q9UG07] synonym: "DVL3" EXACT [UniProtKB:Q9UG07] synonym: "hCG_40299" EXACT [UniProtKB:Q9UG07] xref: EMBL:AL110278 xref: EMBL:CH471052 xref: HGNC:HGNC:3087 xref: UniGene:Hs.388116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059119 ! Q9UG07_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021279 name: LPHH1_human def: "Latrophilin-2 gene" [UniProtKB:Q9UJ49] xref: EMBL:AJ244513 xref: HGNC:HGNC:18582 xref: UniGene:Hs.24212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059169 ! Q9UJ49_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021280 name: OR17-1_human def: "Olfactory receptor 17-1 gene" [UniProtKB:Q9UL14] xref: EMBL:AF095725 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059212 ! Q9UL14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021281 name: PDE10A2_human def: "3',5'-cyclic nucleotide phosphodiesterase 10A2 gene" [UniProtKB:Q9ULW9] xref: EMBL:AB026816 xref: HGNC:HGNC:8772 xref: UniGene:Hs.584856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059237 ! Q9ULW9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021282 name: OR1E3P_human def: "Olfactory receptor 17-210 gene" [UniProtKB:Q9UM77] synonym: "OLFR 17-210" EXACT [UniProtKB:Q9UM77] xref: EMBL:U53583 xref: HGNC:HGNC:8191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059240 ! Q9UM77_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021283 name: OR52K3P_human def: "Putative uncharacterized protein gene" [UniProtKB:Q9Y347] xref: EMBL:AF143328 xref: HGNC:HGNC:15224 xref: UniGene:Hs.162035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059331 ! Q9Y347_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021284 name: GARNL2P_human def: "Putative uncharacterized protein DKFZp566D133 gene" [UniProtKB:Q9Y408] synonym: "DKFZp566D133" EXACT [UniProtKB:Q9Y408] xref: EMBL:AL050050 xref: HGNC:HGNC:17770 xref: UniGene:Hs.113150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059346 ! Q9Y408_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0021285 name: HPV45 E7_human def: "E7 protein gene" [UniProtKB:Q9Y4Y3] xref: EMBL:AJ242956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059367 ! Q9Y4Y3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022019 name: SLC1A5_human def: "Neutral amino acid transporter B(0) gene" [UniProtKB:Q15758] synonym: "ASCT2" EXACT [UniProtKB:Q15758] synonym: "M7V1" EXACT [UniProtKB:Q15758] synonym: "RDR" EXACT [UniProtKB:Q15758] synonym: "RDRC" EXACT [UniProtKB:Q15758] xref: EMBL:AF102826 xref: EMBL:AF105423 xref: EMBL:AF334818 xref: EMBL:BC000062 xref: EMBL:U53347 xref: HGNC:HGNC:10943 xref: UniGene:Hs.631582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063082 ! AAAT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022020 name: ABCF1_human def: "ATP-binding cassette sub-family F member 1 gene" [UniProtKB:Q8NE71] synonym: "ABC50" EXACT [UniProtKB:Q8NE71] xref: EMBL:AB088096 xref: EMBL:AF027302 xref: EMBL:AL662800 xref: EMBL:AL662825 xref: EMBL:AL832430 xref: EMBL:BA000025 xref: EMBL:BC034488 xref: EMBL:BX000357 xref: HGNC:HGNC:70 xref: UniGene:Hs.655285 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063464 ! ABCF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022021 name: ABLIM1_human def: "Actin-binding LIM protein 1 gene" [UniProtKB:O14639] synonym: "ABLIM" EXACT [UniProtKB:O14639] synonym: "KIAA0059" EXACT [UniProtKB:O14639] synonym: "LIMAB1" EXACT [UniProtKB:O14639] xref: EMBL:AF005654 xref: EMBL:AL133384 xref: EMBL:AL354873 xref: EMBL:BC002448 xref: EMBL:CR749819 xref: EMBL:D31883 xref: HGNC:HGNC:78 xref: UniGene:Hs.438236 xref: UniGene:Hs.538331 xref: UniGene:Hs.593868 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027190 ! ABLM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022022 name: ABLIM3_human def: "Actin-binding LIM protein 3 gene" [UniProtKB:O94929] synonym: "HMFN1661" EXACT [UniProtKB:O94929] synonym: "KIAA0843" EXACT [UniProtKB:O94929] xref: EMBL:AB020650 xref: EMBL:AB075881 xref: EMBL:AK289736 xref: EMBL:AL833021 xref: EMBL:BC001665 xref: EMBL:DQ413174 xref: HGNC:HGNC:29132 xref: UniGene:Hs.49688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063365 ! ABLM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022023 name: ACCN1_human def: "Amiloride-sensitive cation channel 1, neuronal gene" [UniProtKB:Q16515] synonym: "ACCN" EXACT [UniProtKB:Q16515] synonym: "BNAC1" EXACT [UniProtKB:Q16515] synonym: "MDEG" EXACT [UniProtKB:Q16515] xref: EMBL:AL834182 xref: EMBL:BC075042 xref: EMBL:BC075043 xref: EMBL:U50352 xref: EMBL:U53212 xref: EMBL:U57352 xref: HGNC:HGNC:99 xref: UniGene:Hs.368417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063267 ! ACCN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022024 name: ACTR1B_human def: "Beta-centractin gene" [UniProtKB:P42025] synonym: "CTRN2" EXACT [UniProtKB:P42025] xref: EMBL:AC017099 xref: EMBL:BC004374 xref: EMBL:BC006372 xref: EMBL:BC010090 xref: EMBL:X82207 xref: HGNC:HGNC:168 xref: UniGene:Hs.98791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063496 ! ACTY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022025 name: AASDHPPT_human def: "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase gene" [UniProtKB:Q9NRN7] synonym: "CGI-80" EXACT [UniProtKB:Q9NRN7] synonym: "HAH-P" EXACT [UniProtKB:Q9NRN7] synonym: "HSPC223" EXACT [UniProtKB:Q9NRN7] synonym: "x0005" EXACT [UniProtKB:Q9NRN7] xref: EMBL:AF136978 xref: EMBL:AF151057 xref: EMBL:AF151838 xref: EMBL:AF201943 xref: EMBL:AF302110 xref: EMBL:AL050073 xref: EMBL:BC015470 xref: EMBL:BC016728 xref: HGNC:HGNC:14235 xref: UniGene:Hs.524009 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062778 ! ADPPT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022026 name: SLC25A4_human def: "ADP/ATP translocase 1 gene" [UniProtKB:P12235] synonym: "ANT1" EXACT [UniProtKB:P12235] xref: EMBL:BC008664 xref: EMBL:BC061589 xref: EMBL:BC063643 xref: EMBL:J02966 xref: EMBL:J03593 xref: EMBL:J04982 xref: HGNC:HGNC:10990 xref: UniGene:Hs.246506 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063358 ! ADT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022027 name: SLC25A6_human def: "ADP/ATP translocase 3 gene" [UniProtKB:P12236] synonym: "ANT3" EXACT [UniProtKB:P12236] synonym: "CDABP0051" EXACT [UniProtKB:P12236] xref: EMBL:AY007135 xref: EMBL:BC007295 xref: EMBL:BC007850 xref: EMBL:BC008737 xref: EMBL:BC008935 xref: EMBL:BC014775 xref: EMBL:BC031912 xref: EMBL:J03592 xref: HGNC:HGNC:10992 xref: UniGene:Hs.350927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063075 ! ADT3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022028 name: AHDC1_human def: "A.T hook DNA-binding motif-containing protein 1 gene" [UniProtKB:Q5TGY3] xref: EMBL:AK125431 xref: EMBL:AL031729 xref: EMBL:BC002677 xref: EMBL:BC014394 xref: EMBL:U79259 xref: HGNC:HGNC:25230 xref: UniGene:Hs.469280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063328 ! AHDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022029 name: AHSA1_human def: "Activator of 90 kDa heat shock protein ATPase homolog 1 gene" [UniProtKB:O95433] synonym: "C14orf3" EXACT [UniProtKB:O95433] synonym: "HSPC322" EXACT [UniProtKB:O95433] xref: EMBL:AF111168 xref: EMBL:AF161440 xref: EMBL:AF164791 xref: EMBL:AJ243310 xref: EMBL:BC000321 xref: EMBL:BC007398 xref: HGNC:HGNC:1189 xref: UniGene:Hs.204041 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063014 ! AHSA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022030 name: AIDA_human def: "Axin interactor, dorsalization associated protein gene" [UniProtKB:Q96BJ3] synonym: "C1orf80" EXACT [UniProtKB:Q96BJ3] xref: EMBL:AK022868 xref: EMBL:AK289865 xref: EMBL:AL392172 xref: EMBL:AL592148 xref: EMBL:AL833718 xref: EMBL:BC015535 xref: EMBL:BC043142 xref: EMBL:BC067805 xref: HGNC:HGNC:25761 xref: UniGene:Hs.156625 xref: UniGene:Hs.534965 xref: UniGene:Hs.701547 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058165 ! AIDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022031 name: Akirin2_human def: "Akirin-2 gene" [UniProtKB:Q53H80] synonym: "C6orf166" EXACT [UniProtKB:Q53H80] xref: EMBL:AK222701 xref: EMBL:AL133211 xref: EMBL:BC000764 xref: EMBL:BC003042 xref: EMBL:BC005051 xref: HGNC:HGNC:21407 xref: UniGene:Hs.485915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062797 ! AKIR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022032 name: ALDH2_human def: "Aldehyde dehydrogenase, mitochondrial precursor gene" [UniProtKB:P05091] synonym: "ALDM" EXACT [UniProtKB:P05091] xref: EMBL:AY621070 xref: EMBL:BC002967 xref: EMBL:BC071839 xref: EMBL:CR456991 xref: EMBL:K03001 xref: EMBL:M20444 xref: EMBL:M20445 xref: EMBL:M20446 xref: EMBL:M20447 xref: EMBL:M20448 xref: EMBL:M20449 xref: EMBL:M20450 xref: EMBL:M20451 xref: EMBL:M20452 xref: EMBL:M20453 xref: EMBL:M20454 xref: EMBL:M20456 xref: EMBL:M26760 xref: EMBL:M54931 xref: EMBL:X05409 xref: EMBL:Y00109 xref: HGNC:HGNC:404 xref: UniGene:Hs.632733 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063375 ! ALDH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022033 name: ALDOA_human def: "Fructose-bisphosphate aldolase A gene" [UniProtKB:P04075] synonym: "ALDA" EXACT [UniProtKB:P04075] xref: EMBL:BC000367 xref: EMBL:BC004333 xref: EMBL:BC010660 xref: EMBL:BC012880 xref: EMBL:BC013614 xref: EMBL:BC015888 xref: EMBL:BC016170 xref: EMBL:BC016800 xref: EMBL:CR541880 xref: EMBL:M11560 xref: EMBL:M21190 xref: EMBL:X05236 xref: EMBL:X12447 xref: HGNC:HGNC:414 xref: UniGene:Hs.513490 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063178 ! ALDOA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022034 name: ANTXR1_human def: "Anthrax toxin receptor 1 precursor gene" [UniProtKB:Q9H6X2] synonym: "ATR" EXACT [UniProtKB:Q9H6X2] synonym: "TEM8" EXACT [UniProtKB:Q9H6X2] xref: EMBL:AF279145 xref: EMBL:AF421380 xref: EMBL:AK001463 xref: EMBL:AK025429 xref: EMBL:BC012074 xref: HGNC:HGNC:21014 xref: UniGene:Hs.165859 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063006 ! ANTR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022035 name: ANTXR2_human def: "Anthrax toxin receptor 2 precursor gene" [UniProtKB:P58335] synonym: "CMG2" EXACT [UniProtKB:P58335] xref: EMBL:AB209913 xref: EMBL:AK055636 xref: EMBL:AK091721 xref: EMBL:AL832851 xref: EMBL:AY040326 xref: EMBL:AY233452 xref: EMBL:BC034001 xref: HGNC:HGNC:21732 xref: UniGene:Hs.162963 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063007 ! ANTR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022036 name: AP1B1_human def: "AP-1 complex subunit beta-1 gene" [UniProtKB:Q10567] synonym: "ADTB1" EXACT [UniProtKB:Q10567] synonym: "BAM22" EXACT [UniProtKB:Q10567] synonym: "CLAPB2" EXACT [UniProtKB:Q10567] xref: EMBL:AF379038 xref: EMBL:AF379039 xref: EMBL:L13939 xref: EMBL:L48038 xref: EMBL:U36250 xref: EMBL:U36251 xref: EMBL:U36252 xref: EMBL:U36253 xref: EMBL:U36254 xref: EMBL:U36255 xref: EMBL:U36256 xref: EMBL:U36257 xref: EMBL:U36258 xref: EMBL:U36259 xref: EMBL:U36260 xref: EMBL:U36261 xref: EMBL:U36262 xref: EMBL:U36263 xref: EMBL:U36264 xref: EMBL:U36265 xref: EMBL:U36266 xref: EMBL:U36267 xref: EMBL:U36268 xref: HGNC:HGNC:554 xref: UniGene:Hs.368794 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063204 ! AP1B1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022037 name: AP1M1_human def: "AP-1 complex subunit mu-1 gene" [UniProtKB:Q9BXS5] synonym: "CLTNM" EXACT [UniProtKB:Q9BXS5] xref: EMBL:AF290613 xref: EMBL:BC017469 xref: HGNC:HGNC:13667 xref: UniGene:Hs.71040 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062862 ! AP1M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022038 name: AP2A1_human def: "AP-2 complex subunit alpha-1 gene" [UniProtKB:O95782] synonym: "ADTAA" EXACT [UniProtKB:O95782] synonym: "CLAPA1" EXACT [UniProtKB:O95782] xref: EMBL:AC006942 xref: EMBL:AC011495 xref: EMBL:AC098783 xref: EMBL:AF289221 xref: EMBL:AL136925 xref: EMBL:BC014214 xref: HGNC:HGNC:561 xref: UniGene:Hs.467125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063354 ! AP2A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022039 name: AP2M1_human def: "AP-2 complex subunit mu-1 gene" [UniProtKB:Q96CW1] synonym: "CLAPM1" EXACT [UniProtKB:Q96CW1] synonym: "KIAA0109" EXACT [UniProtKB:Q96CW1] xref: EMBL:AC131235 xref: EMBL:BC004996 xref: EMBL:BC013796 xref: EMBL:BC014030 xref: EMBL:BT007308 xref: EMBL:CH471052 xref: EMBL:D63475 xref: EMBL:U36188 xref: HGNC:HGNC:564 xref: UniGene:Hs.518460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062824 ! AP2M1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022040 name: APBA1_human def: "Amyloid beta A4 precursor protein-binding family A member 1 gene" [UniProtKB:Q02410] synonym: "MINT1" EXACT [UniProtKB:Q02410] synonym: "X11" EXACT [UniProtKB:Q02410] xref: EMBL:AF029106 xref: EMBL:AF047347 xref: EMBL:AL353693 xref: EMBL:AL355140 xref: EMBL:L04953 xref: HGNC:HGNC:578 xref: UniGene:Hs.695952 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063022 ! APBA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022041 name: APBB3_human def: "Amyloid beta A4 precursor protein-binding family B member 3 gene" [UniProtKB:O95704] synonym: "FE65L2" EXACT [UniProtKB:O95704] xref: EMBL:AB018247 xref: EMBL:AB024745 xref: EMBL:AF224708 xref: EMBL:AF224709 xref: EMBL:AF224710 xref: EMBL:AF224711 xref: EMBL:BC125187 xref: HGNC:HGNC:20708 xref: UniGene:Hs.529449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063259 ! APBB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022042 name: APPBP2_human def: "Amyloid protein-binding protein 2 gene" [UniProtKB:Q92624] synonym: "KIAA0228" EXACT [UniProtKB:Q92624] synonym: "PAT1" EXACT [UniProtKB:Q92624] xref: EMBL:AF017782 xref: EMBL:BC018121 xref: EMBL:D86981 xref: HGNC:HGNC:622 xref: UniGene:Hs.84084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062805 ! APBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022043 name: APEX2_human def: "DNA-(apurinic or apyrimidinic site) lyase 2 gene" [UniProtKB:Q9UBZ4] synonym: "APE2" EXACT [UniProtKB:Q9UBZ4] synonym: "APEXL2" EXACT [UniProtKB:Q9UBZ4] synonym: "XTH2" EXACT [UniProtKB:Q9UBZ4] xref: EMBL:AB021260 xref: EMBL:AB049211 xref: EMBL:AF119046 xref: EMBL:AJ011311 xref: EMBL:AL020991 xref: EMBL:AY884244 xref: EMBL:BC002959 xref: HGNC:HGNC:17889 xref: UniGene:Hs.659558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062803 ! APEX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022044 name: APMAP_human def: "Adipocyte plasma membrane-associated protein gene" [UniProtKB:Q9HDC9] synonym: "C20orf3" EXACT [UniProtKB:Q9HDC9] synonym: "UNQ1869/PRO4305" EXACT [UniProtKB:Q9HDC9] xref: EMBL:AB033767 xref: EMBL:AK025834 xref: EMBL:AK026866 xref: EMBL:AL035661 xref: EMBL:AY359076 xref: EMBL:BC003501 xref: HGNC:HGNC:13238 xref: UniGene:Hs.472330 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063532 ! APMAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022045 name: APOM_human def: "Apolipoprotein M gene" [UniProtKB:O95445] synonym: "G3A" EXACT [UniProtKB:O95445] synonym: "HSPC336" EXACT [UniProtKB:O95445] synonym: "NG20" EXACT [UniProtKB:O95445] xref: EMBL:AF118393 xref: EMBL:AF129756 xref: EMBL:AF161454 xref: EMBL:AJ245434 xref: EMBL:AL662801 xref: EMBL:AL670886 xref: EMBL:AL805934 xref: EMBL:BA000025 xref: EMBL:BC020683 xref: HGNC:HGNC:13916 xref: UniGene:Hs.534468 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063404 ! APOM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022046 name: AQP5_human def: "Aquaporin-5 gene" [UniProtKB:P55064] xref: EMBL:BC032946 xref: EMBL:U46566 xref: EMBL:U46567 xref: EMBL:U46568 xref: EMBL:U46569 xref: HGNC:HGNC:638 xref: UniGene:Hs.298023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062844 ! AQP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022047 name: RAD54L2_human def: "Helicase ARIP4 gene" [UniProtKB:Q9Y4B4] synonym: "ARIP4" EXACT [UniProtKB:Q9Y4B4] synonym: "KIAA0809" EXACT [UniProtKB:Q9Y4B4] xref: EMBL:AB018352 xref: EMBL:AC099050 xref: EMBL:AC113933 xref: EMBL:BC001474 xref: EMBL:BC024298 xref: HGNC:HGNC:29123 xref: UniGene:Hs.105399 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063320 ! ARIP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022048 name: ARMC7_human def: "Armadillo repeat-containing protein 7 gene" [UniProtKB:Q9H6L4] xref: EMBL:AK025813 xref: EMBL:BC011728 xref: HGNC:HGNC:26168 xref: UniGene:Hs.413047 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062796 ! ARMC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022049 name: ACTR2_human def: "Actin-related protein 2 gene" [UniProtKB:P61160] synonym: "ARP2" EXACT [UniProtKB:P61160] xref: EMBL:AF006082 xref: EMBL:BC014546 xref: HGNC:HGNC:169 xref: UniGene:Hs.643727 xref: UniGene:Hs.699451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028186 ! ARP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022050 name: ARPC4_human def: "Actin-related protein 2/3 complex subunit 4 gene" [UniProtKB:P59998] synonym: "ARC20" EXACT [UniProtKB:P59998] xref: EMBL:AF006087 xref: EMBL:AF019888 xref: EMBL:BC012596 xref: HGNC:HGNC:707 xref: UniGene:Hs.323342 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063364 ! ARPC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022051 name: ASAH1_human def: "Acid ceramidase precursor gene" [UniProtKB:Q13510] synonym: "ASAH" EXACT [UniProtKB:Q13510] xref: EMBL:AC124242 xref: EMBL:AF220172 xref: EMBL:AF220173 xref: EMBL:AF220175 xref: EMBL:BC016481 xref: EMBL:U47674 xref: EMBL:U70063 xref: HGNC:HGNC:735 xref: UniGene:Hs.527412 xref: UniGene:Hs.633993 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063392 ! ASAH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022052 name: ASGR1_human def: "Asialoglycoprotein receptor 1 gene" [UniProtKB:P07306] xref: EMBL:AB070933 xref: EMBL:BC032130 xref: EMBL:M10058 xref: HGNC:HGNC:742 xref: UniGene:Hs.12056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019141 ! ASGR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022053 name: ASS1_human def: "Argininosuccinate synthase gene" [UniProtKB:P00966] synonym: "ASS" EXACT [UniProtKB:P00966] xref: EMBL:AK027126 xref: EMBL:AY034076 xref: EMBL:BC009243 xref: EMBL:BC021676 xref: EMBL:BC052288 xref: EMBL:L00079 xref: EMBL:L00080 xref: EMBL:L00081 xref: EMBL:L00082 xref: EMBL:L00083 xref: EMBL:L00084 xref: EMBL:M34903 xref: EMBL:X01630 xref: HGNC:HGNC:758 xref: UniGene:Hs.160786 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063252 ! ASSY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022054 name: ATP2A3_human def: "Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 gene" [UniProtKB:Q93084] xref: EMBL:AF068220 xref: EMBL:AF068221 xref: EMBL:AF458228 xref: EMBL:AF458229 xref: EMBL:BC035729 xref: EMBL:S68239 xref: EMBL:Y15724 xref: EMBL:Y15725 xref: EMBL:Y15726 xref: EMBL:Y15727 xref: EMBL:Y15728 xref: EMBL:Y15729 xref: EMBL:Y15730 xref: EMBL:Y15737 xref: EMBL:Y15738 xref: EMBL:Z69880 xref: EMBL:Z69881 xref: HGNC:HGNC:813 xref: UniGene:Hs.513870 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063203 ! AT2A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022055 name: ATXN7L1_human def: "Ataxin-7-like protein 1 gene" [UniProtKB:Q9ULK2] synonym: "ATXN7L4" EXACT [UniProtKB:Q9ULK2] synonym: "KIAA1218" EXACT [UniProtKB:Q9ULK2] xref: EMBL:AB033044 xref: EMBL:BC030616 xref: HGNC:HGNC:22210 xref: UniGene:Hs.489603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063151 ! AT7L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022056 name: ATXN7L2_human def: "Ataxin-7-like protein 2 gene" [UniProtKB:Q5T6C5] xref: EMBL:AL355145 xref: HGNC:HGNC:28713 xref: UniGene:Hs.118248 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063221 ! AT7L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022057 name: ATAD3A_human def: "ATPase family AAA domain-containing protein 3A gene" [UniProtKB:Q9NVI7] xref: EMBL:AK001571 xref: EMBL:AK091144 xref: EMBL:AL645728 xref: EMBL:BC007803 xref: EMBL:BC011814 xref: EMBL:BC014101 xref: EMBL:BC033109 xref: EMBL:BC063607 xref: HGNC:HGNC:25567 xref: UniGene:Hs.655253 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063202 ! ATD3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022058 name: ATG12_human def: "Autophagy-related protein 12 gene" [UniProtKB:O94817] synonym: "APG12" EXACT [UniProtKB:O94817] synonym: "APG12L" EXACT [UniProtKB:O94817] xref: EMBL:AB017507 xref: EMBL:BC011033 xref: EMBL:BC012266 xref: HGNC:HGNC:588 xref: UniGene:Hs.264482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062923 ! ATG12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022059 name: ATPAF2_human def: "ATP synthase mitochondrial F1 complex assembly factor 2 precursor gene" [UniProtKB:Q8N5M1] synonym: "ATP12" EXACT [UniProtKB:Q8N5M1] synonym: "LP3663" EXACT [UniProtKB:Q8N5M1] xref: EMBL:AC087163 xref: EMBL:AK290257 xref: EMBL:AY203943 xref: EMBL:BC004114 xref: EMBL:BC032126 xref: EMBL:CH471196 xref: HGNC:HGNC:18802 xref: UniGene:Hs.528889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063342 ! ATPF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022060 name: ATP5J2_human def: "ATP synthase subunit f, mitochondrial gene" [UniProtKB:P56134] synonym: "ATP5JL" EXACT [UniProtKB:P56134] xref: EMBL:AF047436 xref: EMBL:AF088918 xref: EMBL:AY046911 xref: EMBL:BC003678 xref: HGNC:HGNC:848 xref: UniGene:Hs.521056 xref: UniGene:Hs.656515 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063395 ! ATPK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022061 name: ATP5O_human def: "ATP synthase subunit O, mitochondrial precursor gene" [UniProtKB:P48047] synonym: "ATPO" EXACT [UniProtKB:P48047] xref: EMBL:AK222962 xref: EMBL:BC021233 xref: EMBL:BC022865 xref: EMBL:BT019836 xref: EMBL:CR456822 xref: EMBL:X83218 xref: HGNC:HGNC:850 xref: UniGene:Hs.409140 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063059 ! ATPO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022062 name: ATXN2L_human def: "Ataxin-2-like protein gene" [UniProtKB:Q8WWM7] synonym: "A2D" EXACT [UniProtKB:Q8WWM7] synonym: "A2LG" EXACT [UniProtKB:Q8WWM7] synonym: "A2LP" EXACT [UniProtKB:Q8WWM7] synonym: "A2RP" EXACT [UniProtKB:Q8WWM7] xref: EMBL:AF034373 xref: EMBL:AJ317970 xref: EMBL:AJ317971 xref: EMBL:AJ317972 xref: EMBL:AJ317973 xref: EMBL:AJ317974 xref: EMBL:AY188334 xref: EMBL:AY188335 xref: EMBL:AY188336 xref: EMBL:AY188337 xref: EMBL:AY188338 xref: EMBL:BC010239 xref: EMBL:BC068012 xref: EMBL:U70671 xref: HGNC:HGNC:31326 xref: UniGene:Hs.460499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063313 ! ATX2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022063 name: AZI2_human def: "5-azacytidine-induced protein 2 gene" [UniProtKB:Q9H6S1] synonym: "NAP1" EXACT [UniProtKB:Q9H6S1] xref: EMBL:AF044917 xref: EMBL:AF044918 xref: EMBL:AK025592 xref: EMBL:AY151386 xref: EMBL:BC001139 xref: EMBL:BC001853 xref: HGNC:HGNC:24002 xref: UniGene:Hs.444724 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063144 ! AZI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022064 name: B3GNT9_human def: "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 gene" [UniProtKB:Q6UX72] synonym: "UNQ1922/PRO4397" EXACT [UniProtKB:Q6UX72] xref: EMBL:AY358485 xref: EMBL:BC012191 xref: EMBL:CH471092 xref: HGNC:HGNC:28714 xref: UniGene:Hs.592061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063288 ! B3GN9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022065 name: B3GNTL1_human def: "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 gene" [UniProtKB:Q67FW5] synonym: "B3GNT8" EXACT [UniProtKB:Q67FW5] xref: EMBL:AY304503 xref: EMBL:AY634364 xref: EMBL:BC019623 xref: HGNC:HGNC:21727 xref: UniGene:Hs.512029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063517 ! B3GNL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022066 name: BAG2_human def: "BAG family molecular chaperone regulator 2 gene" [UniProtKB:O95816] xref: EMBL:AF095192 xref: EMBL:AL031321 xref: EMBL:AL050287 xref: EMBL:AL136311 xref: EMBL:BC125039 xref: EMBL:CR533496 xref: HGNC:HGNC:938 xref: UniGene:Hs.55220 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063043 ! BAG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022067 name: BAG5_human def: "BAG family molecular chaperone regulator 5 gene" [UniProtKB:Q9UL15] synonym: "KIAA0873" EXACT [UniProtKB:Q9UL15] xref: EMBL:AB020680 xref: EMBL:AF095195 xref: EMBL:BC044216 xref: EMBL:BC050551 xref: HGNC:HGNC:941 xref: UniGene:Hs.5443 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063079 ! BAG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022068 name: BAHD1_human def: "Bromo adjacent homology domain-containing 1 protein gene" [UniProtKB:Q8TBE0] synonym: "KIAA0945" EXACT [UniProtKB:Q8TBE0] xref: EMBL:AB023162 xref: EMBL:AC013356 xref: EMBL:AL833923 xref: EMBL:BC022782 xref: HGNC:HGNC:29153 xref: UniGene:Hs.22109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062793 ! BAHD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022069 name: BAMBI_human def: "BMP and activin membrane-bound inhibitor homolog precursor gene" [UniProtKB:Q13145] synonym: "NMA" EXACT [UniProtKB:Q13145] xref: EMBL:AL161936 xref: EMBL:BC019252 xref: EMBL:BT006820 xref: EMBL:U23070 xref: EMBL:U29188 xref: EMBL:U29189 xref: HGNC:HGNC:30251 xref: UniGene:Hs.533336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062798 ! BAMBI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022070 name: BCA3_human def: "Proline-rich protein BCA3 gene" [UniProtKB:Q9NQ31] synonym: "C11orf17" EXACT [UniProtKB:Q9NQ31] xref: EMBL:AF493783 xref: EMBL:AF493784 xref: EMBL:AF493785 xref: EMBL:AF493786 xref: EMBL:AF512007 xref: EMBL:AJ400877 xref: EMBL:AK075308 xref: EMBL:BC030996 xref: HGNC:HGNC:1170 xref: UniGene:Hs.131180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063233 ! BCA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022071 name: BCORL1_human def: "BCoR-like protein 1 gene" [UniProtKB:Q5H9F3] xref: EMBL:AK074089 xref: EMBL:AK124676 xref: EMBL:AL096777 xref: EMBL:AL136450 xref: EMBL:Z82208 xref: HGNC:HGNC:25657 xref: UniGene:Hs.496748 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056438 ! BCORL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022072 name: BLMH_human def: "Bleomycin hydrolase gene" [UniProtKB:Q13867] xref: EMBL:AF091082 xref: EMBL:AK223403 xref: EMBL:BC003616 xref: EMBL:BT007018 xref: EMBL:X92106 xref: HGNC:HGNC:1059 xref: UniGene:Hs.371914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063445 ! BLMH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022073 name: BMP1_human def: "Bone morphogenetic protein 1 precursor gene" [UniProtKB:P13497] synonym: "PCOLC" EXACT [UniProtKB:P13497] xref: EMBL:L35278 xref: EMBL:L35279 xref: EMBL:M22488 xref: EMBL:U50330 xref: EMBL:Y08723 xref: EMBL:Y08724 xref: EMBL:Y08725 xref: HGNC:HGNC:1067 xref: UniGene:Hs.1274 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062974 ! BMP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022074 name: BRP44L_human def: "Brain protein 44-like protein gene" [UniProtKB:Q9Y5U8] synonym: "CGI-129" EXACT [UniProtKB:Q9Y5U8] synonym: "HSPC040" EXACT [UniProtKB:Q9Y5U8] synonym: "PNAS-115" EXACT [UniProtKB:Q9Y5U8] xref: EMBL:AF125101 xref: EMBL:AF151887 xref: EMBL:AF275811 xref: EMBL:AL022069 xref: EMBL:BC000810 xref: HGNC:HGNC:21606 xref: UniGene:Hs.172755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063470 ! BR44L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022075 name: BRI3BP_human def: "BRI3-binding protein gene" [UniProtKB:Q8WY22] synonym: "KG19" EXACT [UniProtKB:Q8WY22] xref: EMBL:AF283671 xref: EMBL:AF284094 xref: EMBL:BC034525 xref: HGNC:HGNC:14251 xref: UniGene:Hs.632740 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063133 ! BRI3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022076 name: BTBD3_human def: "BTB/POZ domain-containing protein 3 gene" [UniProtKB:Q9Y2F9] synonym: "KIAA0952" EXACT [UniProtKB:Q9Y2F9] xref: EMBL:AB023169 xref: EMBL:AL035448 xref: HGNC:HGNC:15854 xref: UniGene:Hs.702048 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063154 ! BTBD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022077 name: CEP170L_human def: "Cep170-like protein gene" [UniProtKB:Q96L14] synonym: "KIAA0470L" EXACT [UniProtKB:Q96L14] xref: EMBL:BC014590 xref: HGNC:HGNC:28364 xref: UniGene:Hs.408293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062851 ! C170L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022078 name: C1QBP_human def: "Complement component 1 Q subcomponent-binding protein, mitochondrial precursor gene" [UniProtKB:Q07021] synonym: "GC1QBP" EXACT [UniProtKB:Q07021] synonym: "HABP1" EXACT [UniProtKB:Q07021] synonym: "SF2P32" EXACT [UniProtKB:Q07021] xref: EMBL:AF275902 xref: EMBL:AF338439 xref: EMBL:BC000435 xref: EMBL:BC013731 xref: EMBL:BT019898 xref: EMBL:BT019899 xref: EMBL:DQ372108 xref: EMBL:L04636 xref: EMBL:M69039 xref: EMBL:X75913 xref: HGNC:HGNC:1243 xref: UniGene:Hs.555866 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063035 ! C1QBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022079 name: COL4A3BP_human def: "Collagen type IV alpha-3-binding protein gene" [UniProtKB:Q9Y5P4] synonym: "CERT" EXACT [UniProtKB:Q9Y5P4] synonym: "STARD11" EXACT [UniProtKB:Q9Y5P4] xref: EMBL:AB036934 xref: EMBL:AB036936 xref: EMBL:AF136450 xref: EMBL:AF232930 xref: EMBL:AF232935 xref: EMBL:AK091851 xref: EMBL:AY453385 xref: EMBL:AY453386 xref: EMBL:BC000102 xref: HGNC:HGNC:2205 xref: UniGene:Hs.270437 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062891 ! C43BP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022080 name: C1orf94_human def: "Uncharacterized protein C1orf94 gene" [UniProtKB:Q6P1W5] xref: EMBL:BC007637 xref: EMBL:BC064845 xref: HGNC:HGNC:28250 xref: UniGene:Hs.194610 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063009 ! CA094_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022081 name: C1orf165_human def: "Coiled-coil domain-containing protein C1orf165 gene" [UniProtKB:Q7L4P6] xref: EMBL:AK021650 xref: EMBL:BC007932 xref: EMBL:BC011804 xref: HGNC:HGNC:25668 xref: UniGene:Hs.475348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062795 ! CA165_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022082 name: C1orf190_human def: "Uncharacterized protein C1orf190 gene" [UniProtKB:Q96LR2] xref: EMBL:AK057892 xref: EMBL:AL672043 xref: EMBL:BC034422 xref: HGNC:HGNC:32327 xref: UniGene:Hs.568642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062781 ! CA190_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022083 name: CA12_human def: "Carbonic anhydrase 12 precursor gene" [UniProtKB:O43570] xref: EMBL:AF037335 xref: EMBL:AF051882 xref: EMBL:BC000278 xref: EMBL:BC011691 xref: EMBL:BC023981 xref: EMBL:BT006656 xref: HGNC:HGNC:1371 xref: UniGene:Hs.210995 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063504 ! CAH12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022084 name: CALU_human def: "Calumenin precursor gene" [UniProtKB:O43852] xref: EMBL:AF013759 xref: EMBL:AF257659 xref: EMBL:AF345637 xref: EMBL:BC013383 xref: EMBL:CR541835 xref: EMBL:U67280 xref: HGNC:HGNC:1458 xref: UniGene:Hs.702061 xref: UniGene:Hs.7753 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063209 ! CALU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022085 name: CANX_human def: "Calnexin precursor gene" [UniProtKB:P27824] xref: EMBL:AJ271880 xref: EMBL:BC003552 xref: EMBL:BC042843 xref: EMBL:L10284 xref: EMBL:L18887 xref: EMBL:M94859 xref: EMBL:M98452 xref: HGNC:HGNC:1473 xref: UniGene:Hs.699155 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063067 ! CALX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022086 name: CALY_human def: "Neuron-specific vesicular protein calcyon gene" [UniProtKB:Q9NYX4] synonym: "DRD1IP" EXACT [UniProtKB:Q9NYX4] xref: EMBL:AF225903 xref: EMBL:AL360181 xref: EMBL:BC038978 xref: EMBL:CH471211 xref: HGNC:HGNC:17938 xref: UniGene:Hs.148680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058986 ! CALY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022087 name: CAPRIN1_human def: "Caprin-1 gene" [UniProtKB:Q14444] synonym: "GPIAP1" EXACT [UniProtKB:Q14444] synonym: "GPIP137" EXACT [UniProtKB:Q14444] synonym: "M11S1" EXACT [UniProtKB:Q14444] xref: EMBL:AC090469 xref: EMBL:BC001731 xref: EMBL:BK001101 xref: EMBL:BK001104 xref: EMBL:CH471064 xref: EMBL:X89572 xref: EMBL:Z48042 xref: HGNC:HGNC:6743 xref: UniGene:Hs.471818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063346 ! CAPR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022088 name: CASC3_human def: "Protein CASC3 gene" [UniProtKB:O15234] synonym: "MLN51" EXACT [UniProtKB:O15234] xref: EMBL:BC044656 xref: EMBL:BC050526 xref: EMBL:X80199 xref: HGNC:HGNC:17040 xref: UniGene:Hs.705465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063246 ! CASC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022089 name: CASS4_human def: "Cas scaffolding protein family member 4 gene" [UniProtKB:Q9NQ75] synonym: "C20orf32" EXACT [UniProtKB:Q9NQ75] synonym: "HEFL" EXACT [UniProtKB:Q9NQ75] xref: EMBL:AJ276678 xref: EMBL:AK027760 xref: EMBL:AL121914 xref: EMBL:BC027951 xref: HGNC:HGNC:15878 xref: UniGene:Hs.473144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022762 ! CASS4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022090 name: C2orf44_human def: "WD repeat-containing protein C2orf44 gene" [UniProtKB:Q9H6R7] synonym: "PP384" EXACT [UniProtKB:Q9H6R7] xref: EMBL:AC104665 xref: EMBL:AF218013 xref: EMBL:AK025598 xref: EMBL:BC035698 xref: EMBL:CH471053 xref: HGNC:HGNC:26157 xref: UniGene:Hs.24624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063461 ! CB044_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022091 name: C2orf65_human def: "Uncharacterized protein C2orf65 gene" [UniProtKB:Q8TC57] xref: EMBL:AC005033 xref: EMBL:AK130161 xref: EMBL:BC014602 xref: EMBL:BC025997 xref: EMBL:CH471053 xref: HGNC:HGNC:25183 xref: UniGene:Hs.348645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062883 ! CB065_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022092 name: CBR1_human def: "Carbonyl reductase [NADPH] 1 gene" [UniProtKB:P16152] synonym: "CBR" EXACT [UniProtKB:P16152] synonym: "CRN" EXACT [UniProtKB:P16152] xref: EMBL:AB003151 xref: EMBL:AB124848 xref: EMBL:AP000688 xref: EMBL:AP001724 xref: EMBL:BC002511 xref: EMBL:BC015640 xref: EMBL:BT019843 xref: EMBL:CR541708 xref: EMBL:EF141836 xref: EMBL:J04056 xref: EMBL:M62420 xref: HGNC:HGNC:1548 xref: UniGene:Hs.606200 xref: UniGene:Hs.88778 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063371 ! CBR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022093 name: CBR3_human def: "Carbonyl reductase [NADPH] 3 gene" [UniProtKB:O75828] xref: EMBL:AB003151 xref: EMBL:AB004854 xref: EMBL:AP000689 xref: EMBL:AP001725 xref: EMBL:BC002812 xref: HGNC:HGNC:1549 xref: UniGene:Hs.154510 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063483 ! CBR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022094 name: C3orf26_human def: "Uncharacterized protein C3orf26 gene" [UniProtKB:Q9BQ75] xref: EMBL:AK291392 xref: EMBL:AK312483 xref: EMBL:BC006475 xref: EMBL:BC006512 xref: HGNC:HGNC:28666 xref: UniGene:Hs.655111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063172 ! CC026_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022095 name: CCDC113_human def: "Coiled-coil domain-containing protein 113 gene" [UniProtKB:Q9H0I3] synonym: "HSPC065" EXACT [UniProtKB:Q9H0I3] xref: EMBL:AF161550 xref: EMBL:AL136785 xref: EMBL:BC126445 xref: EMBL:BC126447 xref: EMBL:CR533506 xref: HGNC:HGNC:25002 xref: UniGene:Hs.11614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063416 ! CC113_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022096 name: CCDC116_human def: "Coiled-coil domain-containing protein 116 gene" [UniProtKB:Q8IYX3] xref: EMBL:AK093365 xref: EMBL:BC033499 xref: HGNC:HGNC:26688 xref: UniGene:Hs.131615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062815 ! CC116_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022097 name: CCDC120_human def: "Coiled-coil domain-containing protein 120 gene" [UniProtKB:Q96HB5] synonym: "JM11" EXACT [UniProtKB:Q96HB5] xref: EMBL:BC008769 xref: EMBL:DQ896186 xref: HGNC:HGNC:28910 xref: UniGene:Hs.522643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062828 ! CC120_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022098 name: CCDC136_human def: "Coiled-coil domain-containing protein 136 gene" [UniProtKB:Q96JN2] synonym: "KIAA1793" EXACT [UniProtKB:Q96JN2] synonym: "NAG6" EXACT [UniProtKB:Q96JN2] xref: EMBL:AB058696 xref: EMBL:AC024952 xref: EMBL:AC025594 xref: EMBL:AF156971 xref: EMBL:AK023500 xref: EMBL:AK124447 xref: EMBL:AL133027 xref: EMBL:BC150331 xref: EMBL:BC152408 xref: EMBL:CH236950 xref: EMBL:CH471070 xref: HGNC:HGNC:22225 xref: UniGene:Hs.521178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063164 ! CC136_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022099 name: CCDC137_human def: "Coiled-coil domain-containing protein 137 gene" [UniProtKB:Q6PK04] xref: EMBL:BC009369 xref: HGNC:HGNC:33451 xref: UniGene:Hs.405942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063473 ! CC137_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022100 name: CCDC28A_human def: "Coiled-coil domain-containing protein 28A gene" [UniProtKB:Q8IWP9] synonym: "C6orf80" EXACT [UniProtKB:Q8IWP9] xref: EMBL:AL050197 xref: EMBL:AL121834 xref: EMBL:AY167571 xref: EMBL:BC013019 xref: EMBL:BC080566 xref: EMBL:BC108717 xref: HGNC:HGNC:21098 xref: UniGene:Hs.412019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063052 ! CC28A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022101 name: CCDC17_human def: "Coiled-coil domain-containing protein 17 gene" [UniProtKB:Q96LX7] xref: EMBL:AK057646 xref: EMBL:AL355480 xref: EMBL:BC029888 xref: EMBL:BC128177 xref: EMBL:BC128178 xref: HGNC:HGNC:26574 xref: UniGene:Hs.18912 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063457 ! CCD17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022102 name: CCDC50_human def: "Coiled-coil domain-containing protein 50 gene" [UniProtKB:Q8IVM0] synonym: "C3orf6" EXACT [UniProtKB:Q8IVM0] xref: EMBL:AJ416916 xref: EMBL:AJ557013 xref: EMBL:BC065004 xref: HGNC:HGNC:18111 xref: UniGene:Hs.478682 xref: UniGene:Hs.592514 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063501 ! CCD50_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022103 name: CCDC91_human def: "Coiled-coil domain-containing protein 91 gene" [UniProtKB:Q7Z6B0] synonym: "GGABP" EXACT [UniProtKB:Q7Z6B0] synonym: "HSD8" EXACT [UniProtKB:Q7Z6B0] xref: EMBL:AK001950 xref: EMBL:AY251168 xref: EMBL:AY289196 xref: EMBL:BC028682 xref: EMBL:CR457277 xref: EMBL:CR749586 xref: HGNC:HGNC:24855 xref: UniGene:Hs.653125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062937 ! CCD91_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022104 name: C4orf14_human def: "Uncharacterized protein C4orf14 gene" [UniProtKB:Q8NC60] xref: EMBL:AK074953 xref: EMBL:AK098215 xref: EMBL:BC004894 xref: HGNC:HGNC:28473 xref: UniGene:Hs.8715 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026813 ! CD014_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022105 name: C4orf17_human def: "Uncharacterized protein C4orf17 gene" [UniProtKB:Q53FE4] xref: EMBL:AK223345 xref: EMBL:AL136838 xref: EMBL:BC069805 xref: EMBL:BC074759 xref: EMBL:CR533542 xref: HGNC:HGNC:25274 xref: UniGene:Hs.97501 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063405 ! CD017_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022106 name: C4orf27_human def: "UPF0609 protein C4orf27 gene" [UniProtKB:Q9NWY4] xref: EMBL:AK000541 xref: EMBL:AL136673 xref: EMBL:BC010367 xref: HGNC:HGNC:26051 xref: UniGene:Hs.406756 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063465 ! CD027_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022107 name: CD177_human def: "CD177 antigen precursor gene" [UniProtKB:Q8N6Q3] synonym: "NB1" EXACT [UniProtKB:Q8N6Q3] synonym: "PRV1" EXACT [UniProtKB:Q8N6Q3] synonym: "UNQ595/PRO1181" EXACT [UniProtKB:Q8N6Q3] xref: EMBL:AF146747 xref: EMBL:AJ290452 xref: EMBL:AJ305326 xref: EMBL:AJ310433 xref: EMBL:AY358932 xref: EMBL:BC029167 xref: EMBL:BT020111 xref: HGNC:HGNC:30072 xref: UniGene:Hs.232165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062866 ! CD177_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022108 name: CD22_human def: "B-cell receptor CD22 precursor gene" [UniProtKB:P20273] synonym: "SIGLEC2" EXACT [UniProtKB:P20273] xref: EMBL:AB012995 xref: EMBL:AB012996 xref: EMBL:AB012997 xref: EMBL:AB012998 xref: EMBL:AB012999 xref: EMBL:AB013000 xref: EMBL:AB013002 xref: EMBL:AB013003 xref: EMBL:AB013004 xref: EMBL:AB013006 xref: EMBL:U62631 xref: EMBL:X52785 xref: EMBL:X59350 xref: HGNC:HGNC:1643 xref: UniGene:Hs.643440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063228 ! CD22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022109 name: CD48_human def: "CD48 antigen precursor gene" [UniProtKB:P09326] synonym: "BCM1" EXACT [UniProtKB:P09326] synonym: "BLAST1" EXACT [UniProtKB:P09326] xref: EMBL:AL121985 xref: EMBL:BC016182 xref: EMBL:M37766 xref: EMBL:M59904 xref: EMBL:M63911 xref: EMBL:X06341 xref: HGNC:HGNC:1683 xref: UniGene:Hs.243564 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063454 ! CD48_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022110 name: CDAN1_human def: "Codanin-1 gene" [UniProtKB:Q8IWY9] synonym: "UNQ664/PRO1295" EXACT [UniProtKB:Q8IWY9] xref: EMBL:AF525398 xref: EMBL:AY358467 xref: EMBL:BC001092 xref: EMBL:BC008333 xref: EMBL:BC008334 xref: EMBL:BC052568 xref: EMBL:BC066640 xref: HGNC:HGNC:1713 xref: UniGene:Hs.599232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063527 ! CDAN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022111 name: CDR2_human def: "Cerebellar degeneration-related protein 2 gene" [UniProtKB:Q01850] synonym: "PCD17" EXACT [UniProtKB:Q01850] xref: EMBL:BC017503 xref: EMBL:D12981 xref: EMBL:M63256 xref: EMBL:S78388 xref: HGNC:HGNC:1799 xref: UniGene:Hs.513430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063018 ! CDR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022112 name: CEP350_human def: "Centrosome-associated protein 350 gene" [UniProtKB:Q5VT06] synonym: "CAP350" EXACT [UniProtKB:Q5VT06] synonym: "GM133" EXACT [UniProtKB:Q5VT06] synonym: "KIAA0480" EXACT [UniProtKB:Q5VT06] xref: EMBL:AF287356 xref: EMBL:AF387614 xref: EMBL:AL390718 xref: EMBL:AL590632 xref: EMBL:AL645487 xref: HGNC:HGNC:24238 xref: UniGene:Hs.413045 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063304 ! CE350_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022113 name: CEP70_human def: "Centrosomal protein of 70 kDa gene" [UniProtKB:Q8NHQ1] synonym: "BITE" EXACT [UniProtKB:Q8NHQ1] xref: EMBL:AF202146 xref: EMBL:AF289495 xref: EMBL:AK023098 xref: EMBL:BC016050 xref: EMBL:BC030598 xref: HGNC:HGNC:29972 xref: UniGene:Hs.531962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062785 ! CEP70_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022114 name: CEP72_human def: "Centrosomal protein of 72 kDa gene" [UniProtKB:Q9P209] synonym: "KIAA1519" EXACT [UniProtKB:Q9P209] xref: EMBL:AB040952 xref: EMBL:AK001427 xref: EMBL:BC000132 xref: EMBL:BC001750 xref: HGNC:HGNC:25547 xref: UniGene:Hs.591741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062905 ! CEP72_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022115 name: CETP_human def: "Cholesteryl ester transfer protein precursor gene" [UniProtKB:P11597] xref: EMBL:AF027656 xref: EMBL:BC025739 xref: EMBL:M30185 xref: EMBL:M32992 xref: EMBL:M32993 xref: EMBL:M32994 xref: EMBL:M32995 xref: EMBL:M32996 xref: EMBL:M32997 xref: EMBL:M32998 xref: EMBL:M83573 xref: EMBL:U71187 xref: HGNC:HGNC:1869 xref: UniGene:Hs.89538 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062887 ! CETP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022116 name: C6orf165_human def: "Uncharacterized protein C6orf165 gene" [UniProtKB:Q8IYR0] xref: EMBL:AK093830 xref: EMBL:AL049697 xref: EMBL:BC035083 xref: HGNC:HGNC:21405 xref: UniGene:Hs.82921 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062922 ! CF165_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022117 name: C7orf34_human def: "Uncharacterized protein C7orf34 precursor gene" [UniProtKB:Q96L11] xref: EMBL:AB083483 xref: EMBL:AB083484 xref: EMBL:BC014596 xref: EMBL:CH236959 xref: HGNC:HGNC:21750 xref: UniGene:Hs.239676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062840 ! CG034_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022118 name: C8orf33_human def: "UPF0488 protein C8orf33 gene" [UniProtKB:Q9H7E9] xref: EMBL:AC139103 xref: EMBL:AK024642 xref: EMBL:BC010001 xref: EMBL:BC015181 xref: EMBL:CH471162 xref: EMBL:CR457330 xref: HGNC:HGNC:26104 xref: UniGene:Hs.169615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063413 ! CH033_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022119 name: C8orf48_human def: "Uncharacterized protein C8orf48 gene" [UniProtKB:Q96LL4] xref: EMBL:AF394908 xref: EMBL:AK058131 xref: EMBL:AK058156 xref: EMBL:BC031245 xref: HGNC:HGNC:26345 xref: UniGene:Hs.104941 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062959 ! CH048_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022120 name: C8orf55_human def: "UPF0670 protein C8orf55 precursor gene" [UniProtKB:Q8WUY1] synonym: "PSEC0098" EXACT [UniProtKB:Q8WUY1] xref: EMBL:AF242773 xref: EMBL:AK075407 xref: EMBL:AK315614 xref: EMBL:BC001311 xref: EMBL:BC019104 xref: HGNC:HGNC:29656 xref: UniGene:Hs.368402 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063289 ! CH055_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022121 name: CHAC1_human def: "Cation transport regulator-like protein 1 gene" [UniProtKB:Q9BUX1] xref: EMBL:BC001683 xref: EMBL:BC001847 xref: EMBL:BC019625 xref: HGNC:HGNC:28680 xref: UniGene:Hs.155569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062948 ! CHAC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022122 name: CHMP2B_human def: "Charged multivesicular body protein 2b gene" [UniProtKB:Q9UQN3] synonym: "CGI-84" EXACT [UniProtKB:Q9UQN3] xref: EMBL:AF151842 xref: EMBL:AK222654 xref: EMBL:AL080122 xref: EMBL:BC001553 xref: EMBL:CR533456 xref: HGNC:HGNC:24537 xref: UniGene:Hs.476930 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062894 ! CHM2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022123 name: C9orf25_human def: "Uncharacterized protein C9orf25 gene" [UniProtKB:Q8IW50] xref: EMBL:AI953059 xref: EMBL:AK096350 xref: EMBL:AK123887 xref: EMBL:AL160270 xref: EMBL:AL356494 xref: EMBL:BC025348 xref: EMBL:BC041009 xref: EMBL:CH471071 xref: HGNC:HGNC:19920 xref: UniGene:Hs.493771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063447 ! CI025_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022124 name: C9orf46_human def: "Transmembrane protein C9orf46 gene" [UniProtKB:Q9HBL7] synonym: "AD025" EXACT [UniProtKB:Q9HBL7] synonym: "MDS030" EXACT [UniProtKB:Q9HBL7] xref: EMBL:AF220050 xref: EMBL:AF225420 xref: EMBL:AK027594 xref: EMBL:AL135786 xref: EMBL:BC008212 xref: HGNC:HGNC:23633 xref: UniGene:Hs.584242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063402 ! CI046_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022125 name: CIC_human def: "Protein capicua homolog gene" [UniProtKB:Q96RK0] synonym: "KIAA0306" EXACT [UniProtKB:Q96RK0] xref: EMBL:AB002304 xref: EMBL:AC006486 xref: EMBL:AF363689 xref: HGNC:HGNC:14214 xref: UniGene:Hs.388236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063013 ! CIC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022126 name: C10orf12_human def: "Uncharacterized protein C10orf12 gene" [UniProtKB:Q8N655] xref: EMBL:AK023084 xref: EMBL:AL049938 xref: EMBL:AL442123 xref: EMBL:BC024315 xref: HGNC:HGNC:23420 xref: UniGene:Hs.14555 xref: UniGene:Hs.427927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062958 ! CJ012_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022127 name: C11orf1_human def: "Uncharacterized protein C11orf1 gene" [UniProtKB:Q9H5F2] xref: EMBL:AJ250229 xref: EMBL:AK027152 xref: EMBL:BC020628 xref: HGNC:HGNC:1163 xref: UniGene:Hs.17546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063446 ! CK001_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022128 name: C11orf16_human def: "Uncharacterized protein C11orf16 gene" [UniProtKB:Q9NQ32] xref: EMBL:AJ400877 xref: EMBL:BC027865 xref: HGNC:HGNC:1169 xref: UniGene:Hs.277349 xref: UniGene:Hs.698487 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0019601 ! CK016_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022129 name: C11orf61_human def: "Uncharacterized protein C11orf61 gene" [UniProtKB:Q6P1R3] xref: EMBL:AK026995 xref: EMBL:AL512691 xref: EMBL:BC064919 xref: HGNC:HGNC:26266 xref: UniGene:Hs.146079 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063536 ! CK061_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022130 name: C11orf65_human def: "Uncharacterized protein C11orf65 gene" [UniProtKB:Q8NCR3] xref: EMBL:BC029536 xref: EMBL:BC059411 xref: HGNC:HGNC:28519 xref: UniGene:Hs.653180 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062822 ! CK065_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022131 name: C11orf68_human def: "Uncharacterized protein C11orf68 gene" [UniProtKB:Q9H3H3] synonym: "BLES03" EXACT [UniProtKB:Q9H3H3] xref: EMBL:AF073483 xref: EMBL:BC004414 xref: EMBL:BC010512 xref: EMBL:BC013185 xref: HGNC:HGNC:28801 xref: UniGene:Hs.433573 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062895 ! CK068_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022132 name: C12orf11_human def: "Uncharacterized protein C12orf11 gene" [UniProtKB:Q9NVM9] xref: EMBL:AK001492 xref: EMBL:AK001499 xref: EMBL:AL137401 xref: EMBL:AY211927 xref: EMBL:BC003081 xref: EMBL:BC008368 xref: HGNC:HGNC:20174 xref: UniGene:Hs.505077 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062783 ! CL011_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022133 name: C12orf12_human def: "Uncharacterized protein C12orf12 gene" [UniProtKB:Q8TC90] xref: EMBL:BC024183 xref: EMBL:BC026075 xref: EMBL:BC027600 xref: EMBL:BC034491 xref: HGNC:HGNC:28373 xref: UniGene:Hs.128574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062842 ! CL012_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022134 name: C12orf31_human def: "UPF0446 protein C12orf31 gene" [UniProtKB:Q9BRT6] xref: EMBL:AK091568 xref: EMBL:BC006002 xref: EMBL:BC070232 xref: EMBL:BC107780 xref: HGNC:HGNC:28229 xref: UniGene:Hs.504820 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062782 ! CL031_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022135 name: CLEC4F_human def: "C-type lectin domain family 4 member F gene" [UniProtKB:Q8N1N0] synonym: "CLECSF13" EXACT [UniProtKB:Q8N1N0] xref: EMBL:AK096429 xref: HGNC:HGNC:25357 xref: UniGene:Hs.681239 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063307 ! CLC4F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022136 name: CLTB_human def: "Clathrin light chain B gene" [UniProtKB:P09497] xref: EMBL:BC006332 xref: EMBL:BC006457 xref: EMBL:CR536577 xref: EMBL:M20469 xref: EMBL:M20470 xref: HGNC:HGNC:2091 xref: UniGene:Hs.484241 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063531 ! CLCB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022137 name: CLDN12_human def: "Claudin-12 gene" [UniProtKB:P56749] xref: EMBL:AJ250713 xref: EMBL:AL136770 xref: EMBL:BC036754 xref: EMBL:BC068532 xref: HGNC:HGNC:2034 xref: UniGene:Hs.258576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063489 ! CLD12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022138 name: CLTC_human def: "Clathrin heavy chain 1 gene" [UniProtKB:Q00610] synonym: "CLH17" EXACT [UniProtKB:Q00610] synonym: "CLTCL2" EXACT [UniProtKB:Q00610] synonym: "KIAA0034" EXACT [UniProtKB:Q00610] xref: EMBL:BC051800 xref: EMBL:BC054489 xref: EMBL:BX640615 xref: EMBL:D21260 xref: EMBL:X55878 xref: HGNC:HGNC:2092 xref: UniGene:Hs.491351 xref: UniGene:Hs.663896 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062997 ! CLH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022139 name: C14orf139_human def: "Uncharacterized protein C14orf139 gene" [UniProtKB:Q9H761] xref: EMBL:AK024929 xref: EMBL:BC008299 xref: EMBL:CR457337 xref: HGNC:HGNC:20353 xref: UniGene:Hs.41502 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063378 ! CN139_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022140 name: CNP_human def: "2',3'-cyclic-nucleotide 3'-phosphodiesterase gene" [UniProtKB:P09543] xref: EMBL:BC001362 xref: EMBL:BC006392 xref: EMBL:BC011046 xref: EMBL:BC028040 xref: EMBL:D13146 xref: EMBL:M19650 xref: EMBL:S46843 xref: EMBL:S46845 xref: EMBL:S46846 xref: EMBL:S46849 xref: EMBL:S50013 xref: EMBL:S50014 xref: EMBL:S50016 xref: EMBL:S50017 xref: HGNC:HGNC:2158 xref: UniGene:Hs.273621 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063255 ! CN37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022141 name: CNRIP1_human def: "CB1 cannabinoid receptor-interacting protein 1 gene" [UniProtKB:Q96F85] synonym: "C2orf32" EXACT [UniProtKB:Q96F85] xref: EMBL:AC015969 xref: EMBL:AK311784 xref: EMBL:AL110235 xref: EMBL:AY144596 xref: EMBL:BC011535 xref: EMBL:BC035125 xref: EMBL:CH471053 xref: HGNC:HGNC:24546 xref: UniGene:Hs.212885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063262 ! CNRP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022142 name: C15orf29_human def: "Uncharacterized protein C15orf29 gene" [UniProtKB:Q9H079] xref: EMBL:AK026210 xref: EMBL:AL136908 xref: EMBL:BC026234 xref: EMBL:BC111000 xref: HGNC:HGNC:26199 xref: UniGene:Hs.633566 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063462 ! CO029_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022143 name: COG4_human def: "Conserved oligomeric Golgi complex subunit 4 gene" [UniProtKB:Q9H9E3] xref: EMBL:AB088369 xref: EMBL:AK022874 xref: EMBL:AK026435 xref: EMBL:AL050101 xref: EMBL:BC000796 xref: EMBL:BC006306 xref: EMBL:BC013347 xref: EMBL:BC072438 xref: HGNC:HGNC:18620 xref: UniGene:Hs.208680 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063023 ! COG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022144 name: COG5_human def: "Conserved oligomeric Golgi complex subunit 5 gene" [UniProtKB:Q9UP83] synonym: "GOLTC1" EXACT [UniProtKB:Q9UP83] synonym: "GTC90" EXACT [UniProtKB:Q9UP83] xref: EMBL:AC002381 xref: EMBL:AC004855 xref: EMBL:AF058718 xref: EMBL:BC068540 xref: EMBL:CH236947 xref: EMBL:CH471070 xref: HGNC:HGNC:14857 xref: UniGene:Hs.239631 xref: UniGene:Hs.97627 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063024 ! COG5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022145 name: COMMD3_human def: "COMM domain-containing protein 3 gene" [UniProtKB:Q9UBI1] synonym: "BUP" EXACT [UniProtKB:Q9UBI1] synonym: "C10orf8" EXACT [UniProtKB:Q9UBI1] xref: EMBL:AF078848 xref: EMBL:AF201948 xref: EMBL:AY542159 xref: EMBL:BC022898 xref: HGNC:HGNC:23332 xref: UniGene:Hs.534398 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063403 ! COMD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022146 name: COMT_human def: "Catechol O-methyltransferase gene" [UniProtKB:P21964] xref: EMBL:AK290440 xref: EMBL:AY341246 xref: EMBL:BC011935 xref: EMBL:BC100018 xref: EMBL:CH471176 xref: EMBL:CR456422 xref: EMBL:CR456997 xref: EMBL:M58525 xref: EMBL:M65212 xref: EMBL:M65213 xref: EMBL:Z26491 xref: HGNC:HGNC:2228 xref: UniGene:Hs.370408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063160 ! COMT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022147 name: COPB1_human def: "Coatomer subunit beta gene" [UniProtKB:P53618] synonym: "COPB" EXACT [UniProtKB:P53618] synonym: "MSTP026" EXACT [UniProtKB:P53618] xref: EMBL:AF084457 xref: EMBL:AF111807 xref: EMBL:AL136593 xref: EMBL:BC037280 xref: EMBL:X82103 xref: HGNC:HGNC:2231 xref: UniGene:Hs.339278 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062988 ! COPB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022148 name: C16orf48_human def: "Uncharacterized protein C16orf48 gene" [UniProtKB:Q9H0I2] synonym: "UNQ6410/PRO21183" EXACT [UniProtKB:Q9H0I2] xref: EMBL:AL136786 xref: EMBL:AY358834 xref: EMBL:BC008284 xref: HGNC:HGNC:25246 xref: UniGene:Hs.307084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062810 ! CP048_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022149 name: NUDT21_human def: "Cleavage and polyadenylation specificity factor subunit 5 gene" [UniProtKB:O43809] synonym: "CFIM25" EXACT [UniProtKB:O43809] synonym: "CPSF25" EXACT [UniProtKB:O43809] synonym: "CPSF5" EXACT [UniProtKB:O43809] xref: EMBL:AJ001810 xref: EMBL:BC001403 xref: EMBL:BX537360 xref: EMBL:CR456919 xref: HGNC:HGNC:13870 xref: UniGene:Hs.528834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062837 ! CPSF5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022150 name: CPSF6_human def: "Cleavage and polyadenylation specificity factor subunit 6 gene" [UniProtKB:Q16630] synonym: "CFIM68" EXACT [UniProtKB:Q16630] xref: EMBL:AK223568 xref: EMBL:BC000714 xref: EMBL:BC005000 xref: EMBL:X67336 xref: EMBL:X67337 xref: HGNC:HGNC:13871 xref: UniGene:Hs.369606 xref: UniGene:Hs.592681 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063126 ! CPSF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022151 name: CPSF7_human def: "Cleavage and polyadenylation specificity factor subunit 7 gene" [UniProtKB:Q8N684] xref: EMBL:AJ275970 xref: EMBL:AK022591 xref: EMBL:AL512759 xref: EMBL:BC018135 xref: EMBL:BX537888 xref: UniGene:Hs.444552 xref: UniGene:Hs.702348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062890 ! CPSF7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022152 name: CPS1_human def: "Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor gene" [UniProtKB:P31327] xref: EMBL:AF154830 xref: EMBL:AF536523 xref: EMBL:AY166970 xref: EMBL:AY166971 xref: EMBL:AY166972 xref: EMBL:AY166973 xref: EMBL:AY166974 xref: EMBL:AY166975 xref: EMBL:AY166976 xref: EMBL:AY166977 xref: EMBL:AY166978 xref: EMBL:AY166979 xref: EMBL:AY166980 xref: EMBL:AY166981 xref: EMBL:AY166982 xref: EMBL:AY166983 xref: EMBL:AY166984 xref: EMBL:AY166985 xref: EMBL:AY166986 xref: EMBL:AY166987 xref: EMBL:AY166988 xref: EMBL:AY166989 xref: EMBL:AY166990 xref: EMBL:AY166991 xref: EMBL:AY166992 xref: EMBL:AY166993 xref: EMBL:AY166994 xref: EMBL:AY166995 xref: EMBL:AY166996 xref: EMBL:AY166997 xref: EMBL:AY166998 xref: EMBL:AY166999 xref: EMBL:AY167000 xref: EMBL:AY167001 xref: EMBL:AY167002 xref: EMBL:AY167003 xref: EMBL:AY167004 xref: EMBL:AY167005 xref: EMBL:AY167006 xref: EMBL:AY167007 xref: EMBL:AY317138 xref: EMBL:BX640601 xref: EMBL:D90282 xref: EMBL:Y15793 xref: HGNC:HGNC:2323 xref: UniGene:Hs.149252 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063232 ! CPSM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022153 name: C18orf56_human def: "Putative uncharacterized protein C18orf56 gene" [UniProtKB:Q8TAI1] xref: EMBL:BC028301 xref: HGNC:HGNC:29553 xref: UniGene:Hs.274959 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062786 ! CR056_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022154 name: C19orf29_human def: "Uncharacterized protein C19orf29 gene" [UniProtKB:Q8WUQ7] xref: EMBL:AC005175 xref: EMBL:AC005542 xref: EMBL:AF155102 xref: EMBL:BC004262 xref: EMBL:BC019848 xref: EMBL:CH471139 xref: HGNC:HGNC:29938 xref: UniGene:Hs.128425 xref: UniGene:Hs.665775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063276 ! CS029_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022155 name: C19orf60_human def: "Uncharacterized protein C19orf60 gene" [UniProtKB:Q96EN9] xref: EMBL:AK000857 xref: EMBL:AK091925 xref: EMBL:BC012078 xref: EMBL:CH471106 xref: HGNC:HGNC:26098 xref: UniGene:Hs.655317 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062838 ! CS060_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022156 name: COPS4_human def: "COP9 signalosome complex subunit 4 gene" [UniProtKB:Q9BT78] synonym: "CSN4" EXACT [UniProtKB:Q9BT78] xref: EMBL:AF100757 xref: EMBL:AK001210 xref: EMBL:BC004302 xref: EMBL:BC009292 xref: EMBL:BC093007 xref: HGNC:HGNC:16702 xref: UniGene:Hs.190384 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022200 ! CSN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022157 name: CSRP2BP_human def: "Cysteine-rich protein 2-binding protein gene" [UniProtKB:Q9H8E8] xref: EMBL:AF252257 xref: EMBL:AK023759 xref: EMBL:AL050321 xref: EMBL:BC007537 xref: EMBL:BC009174 xref: HGNC:HGNC:15904 xref: UniGene:Hs.488051 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062942 ! CSR2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022158 name: CSTF2_human def: "Cleavage stimulation factor 64 kDa subunit gene" [UniProtKB:P33240] xref: EMBL:BC017712 xref: EMBL:BC033135 xref: EMBL:BT009778 xref: EMBL:M85085 xref: EMBL:Z83819 xref: EMBL:Z95327 xref: HGNC:HGNC:2484 xref: UniGene:Hs.132370 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063344 ! CSTF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022159 name: C20orf160_human def: "Uncharacterized protein C20orf160 gene" [UniProtKB:Q9NUG4] xref: EMBL:AK057090 xref: EMBL:AL031658 xref: EMBL:BC030254 xref: EMBL:BC032455 xref: HGNC:HGNC:16153 xref: UniGene:Hs.382151 xref: UniGene:Hs.638682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063372 ! CT160_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022160 name: CTLA4_human def: "Cytotoxic T-lymphocyte protein 4 precursor gene" [UniProtKB:P16410] synonym: "CD152" EXACT [UniProtKB:P16410] xref: EMBL:AC010138 xref: EMBL:AF142144 xref: EMBL:AF411058 xref: EMBL:AF414120 xref: EMBL:BC074842 xref: EMBL:BC074893 xref: EMBL:DQ357942 xref: EMBL:M37243 xref: EMBL:M37244 xref: EMBL:M37245 xref: EMBL:M74363 xref: HGNC:HGNC:2505 xref: UniGene:Hs.247824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063145 ! CTLA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022161 name: CATSPER1_human def: "Cation channel sperm-associated protein 1 gene" [UniProtKB:Q8NEC5] xref: EMBL:AF407333 xref: EMBL:BC032950 xref: EMBL:BC036522 xref: HGNC:HGNC:17116 xref: UniGene:Hs.189105 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062879 ! CTSR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022162 name: CXorf20_human def: "Uncharacterized protein CXorf20 gene" [UniProtKB:Q8NDZ0] xref: EMBL:AL096763 xref: EMBL:BC037301 xref: HGNC:HGNC:28509 xref: UniGene:Hs.403802 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031918 ! CX020_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022163 name: CXorf26_human def: "UPF0368 protein Cxorf26 gene" [UniProtKB:Q9BVG4] xref: EMBL:BC001220 xref: EMBL:BC051894 xref: HGNC:HGNC:28790 xref: UniGene:Hs.370100 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063537 ! CX026_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022164 name: CXorf45_human def: "Uncharacterized protein CXorf45 gene" [UniProtKB:Q9H5U8] xref: EMBL:AK026671 xref: EMBL:AK223154 xref: EMBL:AL049563 xref: EMBL:BC117377 xref: EMBL:BC117379 xref: HGNC:HGNC:26240 xref: UniGene:Hs.443061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063338 ! CX045_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022165 name: CXorf40A_human def: "Protein CXorf40A gene" [UniProtKB:Q8TE69] synonym: "CXorf40" EXACT [UniProtKB:Q8TE69] synonym: "EOLA1" EXACT [UniProtKB:Q8TE69] xref: EMBL:AF011889 xref: EMBL:AY074889 xref: EMBL:BC065539 xref: EMBL:BC104930 xref: EMBL:BC104932 xref: EMBL:L43580 xref: HGNC:HGNC:28089 xref: UniGene:Hs.654738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063264 ! CX04A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022166 name: CXADR_human def: "Coxsackievirus and adenovirus receptor precursor gene" [UniProtKB:P78310] synonym: "CAR" EXACT [UniProtKB:P78310] xref: EMBL:AF124598 xref: EMBL:AF169360 xref: EMBL:AF169361 xref: EMBL:AF169362 xref: EMBL:AF169363 xref: EMBL:AF169364 xref: EMBL:AF169365 xref: EMBL:AF169366 xref: EMBL:AF200465 xref: EMBL:AF242862 xref: EMBL:AF242864 xref: EMBL:AF242865 xref: EMBL:AY072910 xref: EMBL:AY072911 xref: EMBL:AY072912 xref: EMBL:BC003684 xref: EMBL:BC010536 xref: EMBL:BT019876 xref: EMBL:CR617256 xref: EMBL:U90716 xref: EMBL:Y07593 xref: HGNC:HGNC:2559 xref: UniGene:Hs.705503 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062878 ! CXAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022167 name: CSTB_human def: "Cystatin-B gene" [UniProtKB:P04080] synonym: "CST6" EXACT [UniProtKB:P04080] synonym: "STFB" EXACT [UniProtKB:P04080] xref: EMBL:AF208234 xref: EMBL:AP001752 xref: EMBL:BC003370 xref: EMBL:BC010532 xref: EMBL:L03558 xref: EMBL:U46692 xref: HGNC:HGNC:2482 xref: UniGene:Hs.695 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063207 ! CYTB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022168 name: CST3_human def: "Cystatin-C precursor gene" [UniProtKB:P01034] xref: EMBL:AL121894 xref: EMBL:BC013083 xref: EMBL:BC110305 xref: EMBL:BT006839 xref: EMBL:CH471133 xref: EMBL:CR541988 xref: EMBL:CR542018 xref: EMBL:M27889 xref: EMBL:M27890 xref: EMBL:M27891 xref: EMBL:X05607 xref: EMBL:X52255 xref: EMBL:X61681 xref: EMBL:X61682 xref: EMBL:X61683 xref: HGNC:HGNC:2475 xref: UniGene:Hs.304682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063321 ! CYTC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022169 name: CYTIP_human def: "Cytohesin-interacting protein gene" [UniProtKB:O60759] synonym: "PSCDBP" EXACT [UniProtKB:O60759] xref: EMBL:AC019201 xref: EMBL:AF068836 xref: EMBL:BC036449 xref: EMBL:L06633 xref: HGNC:HGNC:9506 xref: UniGene:Hs.270 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054577 ! CYTIP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022170 name: DYNC1LI2_human def: "Cytoplasmic dynein 1 light intermediate chain 2 gene" [UniProtKB:O43237] synonym: "DNCLI2" EXACT [UniProtKB:O43237] synonym: "LIC2" EXACT [UniProtKB:O43237] xref: EMBL:AF035812 xref: EMBL:BC025959 xref: HGNC:HGNC:2966 xref: UniGene:Hs.369068 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063409 ! DC1L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022171 name: DCD_human def: "Dermcidin precursor gene" [UniProtKB:P81605] synonym: "AIDD" EXACT [UniProtKB:P81605] synonym: "DSEP" EXACT [UniProtKB:P81605] xref: EMBL:AF144011 xref: EMBL:AF418981 xref: EMBL:AY044239 xref: EMBL:BC062682 xref: EMBL:BC069108 xref: HGNC:HGNC:14669 xref: UniGene:Hs.350570 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063170 ! DCD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022172 name: DCTD_human def: "Deoxycytidylate deaminase gene" [UniProtKB:P32321] xref: EMBL:BC001286 xref: EMBL:L12136 xref: EMBL:L39874 xref: HGNC:HGNC:2710 xref: UniGene:Hs.183850 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062960 ! DCTD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022173 name: DDX19A_human def: "ATP-dependent RNA helicase DDX19A gene" [UniProtKB:Q9NUU7] synonym: "DDX19L" EXACT [UniProtKB:Q9NUU7] xref: EMBL:AK001988 xref: EMBL:AK223262 xref: EMBL:AL832970 xref: EMBL:BC005162 xref: EMBL:BC006544 xref: HGNC:HGNC:25628 xref: UniGene:Hs.656037 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062772 ! DD19A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022174 name: DDX17_human def: "Probable ATP-dependent RNA helicase DDX17 gene" [UniProtKB:Q92841] xref: EMBL:AL713763 xref: EMBL:BC000595 xref: EMBL:CR456432 xref: EMBL:U59321 xref: EMBL:Z97056 xref: HGNC:HGNC:2740 xref: UniGene:Hs.528305 xref: UniGene:Hs.665429 xref: UniGene:Hs.705651 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062841 ! DDX17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022175 name: DDX18_human def: "ATP-dependent RNA helicase DDX18 gene" [UniProtKB:Q9NVP1] xref: EMBL:AK001467 xref: EMBL:BC001238 xref: EMBL:BC003360 xref: EMBL:BC024739 xref: EMBL:CR457060 xref: EMBL:X98743 xref: HGNC:HGNC:2741 xref: UniGene:Hs.363492 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063505 ! DDX18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022176 name: DDX23_human def: "Probable ATP-dependent RNA helicase DDX23 gene" [UniProtKB:Q9BUQ8] xref: EMBL:AF026402 xref: EMBL:BC002366 xref: HGNC:HGNC:17347 xref: UniGene:Hs.130098 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063187 ! DDX23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022177 name: DDX39_human def: "ATP-dependent RNA helicase DDX39 gene" [UniProtKB:O00148] xref: EMBL:AK026614 xref: EMBL:BC001009 xref: EMBL:U90426 xref: HGNC:HGNC:17821 xref: UniGene:Hs.311609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062897 ! DDX39_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022178 name: DDX50_human def: "ATP-dependent RNA helicase DDX50 gene" [UniProtKB:Q9BQ39] xref: EMBL:AF334103 xref: EMBL:BC000210 xref: EMBL:BC000272 xref: EMBL:BC018637 xref: HGNC:HGNC:17906 xref: UniGene:Hs.522984 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063176 ! DDX50_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022179 name: DDX52_human def: "Probable ATP-dependent RNA helicase DDX52 gene" [UniProtKB:Q9Y2R4] synonym: "HUSSY-19" EXACT [UniProtKB:Q9Y2R4] synonym: "ROK1" EXACT [UniProtKB:Q9Y2R4] xref: EMBL:AF077033 xref: EMBL:AJ010840 xref: EMBL:AK001652 xref: EMBL:AK093661 xref: EMBL:BC041785 xref: HGNC:HGNC:20038 xref: UniGene:Hs.590937 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063171 ! DDX52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022180 name: DDX58_human def: "Probable ATP-dependent RNA helicase DDX58 gene" [UniProtKB:O95786] xref: EMBL:AF038963 xref: EMBL:AL137608 xref: EMBL:AL161783 xref: EMBL:AL353671 xref: EMBL:BX647917 xref: HGNC:HGNC:19102 xref: UniGene:Hs.190622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063236 ! DDX58_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022181 name: DEFB1_human def: "Beta-defensin 1 precursor gene" [UniProtKB:P60022] synonym: "BD1" EXACT [UniProtKB:P60022] synonym: "HBD1" EXACT [UniProtKB:P60022] xref: EMBL:BC033298 xref: EMBL:BC047677 xref: EMBL:U50930 xref: EMBL:U50931 xref: EMBL:U73945 xref: EMBL:X92744 xref: EMBL:Z50788 xref: HGNC:HGNC:2766 xref: UniGene:Hs.32949 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055595 ! DEFB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022182 name: DEFB4_human def: "Beta-defensin 2 precursor gene" [UniProtKB:O15263] synonym: "DEFB102" EXACT [UniProtKB:O15263] synonym: "DEFB2" EXACT [UniProtKB:O15263] xref: EMBL:AF040153 xref: EMBL:AF071216 xref: EMBL:AJ000152 xref: EMBL:BC069285 xref: EMBL:BC093983 xref: EMBL:BC093985 xref: EMBL:Z71389 xref: HGNC:HGNC:2767 xref: UniGene:Hs.105924 xref: UniGene:Hs.646758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054421 ! DEFB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022183 name: DGCR6L_human def: "Protein DGCR6L gene" [UniProtKB:Q9BY27] xref: EMBL:AF228708 xref: EMBL:BC000682 xref: EMBL:CR456361 xref: HGNC:HGNC:18551 xref: UniGene:Hs.410965 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062868 ! DGC6L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022184 name: HSD17B4_human def: "Peroxisomal multifunctional enzyme type 2 gene" [UniProtKB:P51659] synonym: "EDH17B4" EXACT [UniProtKB:P51659] xref: EMBL:AF057720 xref: EMBL:AF057721 xref: EMBL:AF057722 xref: EMBL:AF057723 xref: EMBL:AF057724 xref: EMBL:AF057725 xref: EMBL:AF057726 xref: EMBL:AF057727 xref: EMBL:AF057728 xref: EMBL:AF057729 xref: EMBL:AF057730 xref: EMBL:AF057731 xref: EMBL:AF057732 xref: EMBL:AF057733 xref: EMBL:AF057734 xref: EMBL:AF057735 xref: EMBL:AF057736 xref: EMBL:AF057737 xref: EMBL:AF057738 xref: EMBL:AF057739 xref: EMBL:AF057740 xref: EMBL:BC003098 xref: EMBL:X87176 xref: HGNC:HGNC:5213 xref: UniGene:Hs.406861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063125 ! DHB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022185 name: DHRS1_human def: "Dehydrogenase/reductase SDR family member 1 gene" [UniProtKB:Q96LJ7] xref: EMBL:AF418205 xref: EMBL:AK058159 xref: EMBL:AL833917 xref: EMBL:BC014057 xref: EMBL:BC015943 xref: EMBL:BX247980 xref: HGNC:HGNC:16445 xref: UniGene:Hs.348350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062847 ! DHRS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022186 name: DHX29_human def: "Putative ATP-dependent RNA helicase DHX29 gene" [UniProtKB:Q7Z478] synonym: "DDX29" EXACT [UniProtKB:Q7Z478] xref: EMBL:AF070639 xref: EMBL:AL079292 xref: EMBL:AL834496 xref: EMBL:AY036974 xref: EMBL:BC056219 xref: EMBL:BX648101 xref: EMBL:BX648269 xref: HGNC:HGNC:15815 xref: UniGene:Hs.696182 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063506 ! DHX29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022187 name: DHX34_human def: "Probable ATP-dependent RNA helicase DHX34 gene" [UniProtKB:Q14147] synonym: "DDX34" EXACT [UniProtKB:Q14147] synonym: "KIAA0134" EXACT [UniProtKB:Q14147] xref: EMBL:D50924 xref: HGNC:HGNC:16719 xref: UniGene:Hs.151706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063450 ! DHX34_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022188 name: DICER1_human def: "Endoribonuclease Dicer gene" [UniProtKB:Q9UPY3] synonym: "DICER" EXACT [UniProtKB:Q9UPY3] synonym: "HERNA" EXACT [UniProtKB:Q9UPY3] synonym: "KIAA0928" EXACT [UniProtKB:Q9UPY3] xref: EMBL:AB023145 xref: EMBL:AB028449 xref: EMBL:AJ132261 xref: HGNC:HGNC:17098 xref: UniGene:Hs.87889 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062982 ! DICER_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022189 name: DIMT1L_human def: "Probable dimethyladenosine transferase gene" [UniProtKB:Q9UNQ2] synonym: "DIMT1" EXACT [UniProtKB:Q9UNQ2] synonym: "HUSSY-05" EXACT [UniProtKB:Q9UNQ2] xref: EMBL:AF091078 xref: EMBL:AF102147 xref: EMBL:AJ009761 xref: EMBL:BC002841 xref: EMBL:BC010874 xref: HGNC:HGNC:30217 xref: UniGene:Hs.533222 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063175 ! DIMT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022190 name: DLD_human def: "Dihydrolipoyl dehydrogenase, mitochondrial precursor gene" [UniProtKB:P09622] synonym: "GCSL" EXACT [UniProtKB:P09622] synonym: "LAD" EXACT [UniProtKB:P09622] synonym: "PHE3" EXACT [UniProtKB:P09622] xref: EMBL:AB209703 xref: EMBL:BC018648 xref: EMBL:BC018696 xref: EMBL:CH236947 xref: EMBL:J03490 xref: EMBL:J03620 xref: EMBL:L13748 xref: EMBL:L13749 xref: EMBL:L13750 xref: EMBL:L13751 xref: EMBL:L13752 xref: EMBL:L13753 xref: EMBL:L13754 xref: EMBL:L13755 xref: EMBL:L13756 xref: EMBL:L13757 xref: EMBL:L13758 xref: EMBL:L13759 xref: EMBL:L13760 xref: EMBL:L13761 xref: EMBL:M99384 xref: HGNC:HGNC:2898 xref: UniGene:Hs.131711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063359 ! DLDH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022191 name: DNAJC7_human def: "DnaJ homolog subfamily C member 7 gene" [UniProtKB:Q99615] synonym: "TPR2" EXACT [UniProtKB:Q99615] synonym: "TTC2" EXACT [UniProtKB:Q99615] xref: EMBL:BC011837 xref: EMBL:BC033772 xref: EMBL:U46571 xref: HGNC:HGNC:12392 xref: UniGene:Hs.500156 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063120 ! DNJC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022192 name: DNPEP_human def: "Aspartyl aminopeptidase gene" [UniProtKB:Q9ULA0] synonym: "ASPEP" EXACT [UniProtKB:Q9ULA0] synonym: "DAP" EXACT [UniProtKB:Q9ULA0] xref: EMBL:AF005050 xref: EMBL:AK001977 xref: EMBL:BC000653 xref: HGNC:HGNC:2981 xref: UniGene:Hs.258551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062954 ! DNPEP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022193 name: DOCK2_human def: "Dedicator of cytokinesis protein 2 gene" [UniProtKB:Q92608] synonym: "KIAA0209" EXACT [UniProtKB:Q92608] xref: EMBL:BC016996 xref: EMBL:BC104900 xref: EMBL:BC113457 xref: EMBL:D86964 xref: HGNC:HGNC:2988 xref: UniGene:Hs.586174 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063281 ! DOCK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022194 name: DPCD_human def: "Protein DPCD gene" [UniProtKB:Q9BVM2] xref: EMBL:AK290154 xref: EMBL:AL110240 xref: EMBL:AL627424 xref: EMBL:AY532267 xref: EMBL:BC001082 xref: EMBL:BC031695 xref: UniGene:Hs.658128 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062924 ! DPCD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022195 name: DPPA4_human def: "Developmental pluripotency-associated protein 4 gene" [UniProtKB:Q7L190] xref: EMBL:AK001575 xref: EMBL:AK022698 xref: EMBL:BC032846 xref: HGNC:HGNC:19200 xref: UniGene:Hs.317659 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062834 ! DPPA4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022196 name: DPY30_human def: "Protein dpy-30 homolog gene" [UniProtKB:Q9C005] xref: EMBL:AF226998 xref: EMBL:BC015970 xref: HGNC:HGNC:24590 xref: UniGene:Hs.531788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062826 ! DPY30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022197 name: DPYSL4_human def: "Dihydropyrimidinase-related protein 4 gene" [UniProtKB:O14531] synonym: "CRMP3" EXACT [UniProtKB:O14531] synonym: "ULIP4" EXACT [UniProtKB:O14531] xref: EMBL:AB006713 xref: EMBL:AL512622 xref: EMBL:Y10976 xref: HGNC:HGNC:3016 xref: UniGene:Hs.100058 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063452 ! DPYL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022198 name: DRG1_human def: "Developmentally-regulated GTP-binding protein 1 gene" [UniProtKB:Q9Y295] synonym: "NEDD3" EXACT [UniProtKB:Q9Y295] xref: EMBL:AF078103 xref: EMBL:AJ005940 xref: EMBL:AL096701 xref: EMBL:AL096702 xref: EMBL:BC019285 xref: EMBL:BC020803 xref: EMBL:BT007237 xref: EMBL:CR456488 xref: EMBL:CR542059 xref: HGNC:HGNC:3029 xref: UniGene:Hs.115242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063453 ! DRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022199 name: DYDC1_human def: "DPY30 domain-containing protein 1 gene" [UniProtKB:Q8WWB3] synonym: "DPY30D1" EXACT [UniProtKB:Q8WWB3] synonym: "RSD-9" EXACT [UniProtKB:Q8WWB3] synonym: "RSD9" EXACT [UniProtKB:Q8WWB3] xref: EMBL:AK125908 xref: EMBL:AL359195 xref: EMBL:AY278322 xref: EMBL:BC019250 xref: HGNC:HGNC:23460 xref: UniGene:Hs.407751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062776 ! DYDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022200 name: DYDC2_human def: "DPY30 domain-containing protein 2 gene" [UniProtKB:Q96IM9] xref: EMBL:AK093378 xref: EMBL:AL359195 xref: EMBL:BC007374 xref: HGNC:HGNC:23468 xref: UniGene:Hs.512782 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062907 ! DYDC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022201 name: DYNLL2_human def: "Dynein light chain 2, cytoplasmic gene" [UniProtKB:Q96FJ2] synonym: "DLC2" EXACT [UniProtKB:Q96FJ2] xref: EMBL:AF112997 xref: EMBL:BC010744 xref: HGNC:HGNC:24596 xref: UniGene:Hs.591176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062812 ! DYL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022202 name: DZIP1_human def: "Zinc finger protein DZIP1 gene" [UniProtKB:Q86YF9] synonym: "DZIP" EXACT [UniProtKB:Q86YF9] synonym: "DZIP2" EXACT [UniProtKB:Q86YF9] synonym: "KIAA0996" EXACT [UniProtKB:Q86YF9] xref: EMBL:AB023213 xref: EMBL:AF272347 xref: EMBL:AF272348 xref: EMBL:AL049931 xref: EMBL:AL139376 xref: EMBL:BC041804 xref: HGNC:HGNC:20908 xref: UniGene:Hs.656580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063270 ! DZIP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022203 name: DZIP3_human def: "E3 ubiquitin-protein ligase DZIP3 gene" [UniProtKB:Q86Y13] synonym: "KIAA0675" EXACT [UniProtKB:Q86Y13] xref: EMBL:AB014575 xref: EMBL:AF279370 xref: EMBL:AY227651 xref: EMBL:AY227652 xref: EMBL:AY227653 xref: EMBL:AY227654 xref: EMBL:BC039018 xref: EMBL:BC056674 xref: EMBL:BC063882 xref: HGNC:HGNC:30938 xref: UniGene:Hs.409210 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063271 ! DZIP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022204 name: EPB41L3_human def: "Band 4.1-like protein 3 gene" [UniProtKB:Q9Y2J2] synonym: "DAL1" EXACT [UniProtKB:Q9Y2J2] synonym: "KIAA0987" EXACT [UniProtKB:Q9Y2J2] xref: EMBL:AB023204 xref: EMBL:AF069072 xref: EMBL:BC006141 xref: EMBL:BC008377 xref: HGNC:HGNC:3380 xref: UniGene:Hs.213394 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062914 ! Q96HL7_HUMAN relationship: codes_for CCO:B0063153 ! E41L3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022205 name: TCEB3CL_human def: "RNA polymerase II transcription factor SIII subunit A3-like-1 gene" [UniProtKB:Q3SY89] xref: EMBL:BC103912 xref: EMBL:BC103913 xref: HGNC:HGNC:31007 xref: UniGene:Hs.631677 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056272 ! EA3L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022206 name: TCEB3CL2_human def: "RNA polymerase II transcription factor SIII subunit A3-like-2 gene" [UniProtKB:A6NLF2] xref: EMBL:AC090373 xref: HGNC:HGNC:33511 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053895 ! EA3L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022207 name: SLC1A1_human def: "Excitatory amino acid transporter 3 gene" [UniProtKB:P43005] synonym: "EAAC1" EXACT [UniProtKB:P43005] synonym: "EAAT3" EXACT [UniProtKB:P43005] xref: EMBL:AB008536 xref: EMBL:AF037982 xref: EMBL:AF074903 xref: EMBL:AF074904 xref: EMBL:AF074905 xref: EMBL:AF074906 xref: EMBL:AF074907 xref: EMBL:AF074908 xref: EMBL:AF074909 xref: EMBL:AF074910 xref: EMBL:AF074911 xref: EMBL:AF143773 xref: EMBL:AL136231 xref: EMBL:AL162587 xref: EMBL:BC033040 xref: EMBL:U03506 xref: EMBL:U06469 xref: EMBL:U08989 xref: HGNC:HGNC:10939 xref: UniGene:Hs.444915 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062832 ! EAA3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022208 name: ECH1_human def: "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor gene" [UniProtKB:Q13011] xref: EMBL:AF030246 xref: EMBL:AF030247 xref: EMBL:AF030248 xref: EMBL:AF030249 xref: EMBL:BC011792 xref: EMBL:BC017408 xref: EMBL:U16660 xref: HGNC:HGNC:3149 xref: UniGene:Hs.196176 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063377 ! ECH1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022209 name: HADHA_human def: "Trifunctional enzyme subunit alpha, mitochondrial precursor gene" [UniProtKB:P40939] synonym: "HADH" EXACT [UniProtKB:P40939] xref: EMBL:BC009235 xref: EMBL:D16480 xref: EMBL:U04627 xref: HGNC:HGNC:4801 xref: UniGene:Hs.516032 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063089 ! ECHA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022210 name: HADHB_human def: "Trifunctional enzyme subunit beta, mitochondrial precursor gene" [UniProtKB:P55084] synonym: "MSTP029" EXACT [UniProtKB:P55084] xref: EMBL:AC010896 xref: EMBL:AF113209 xref: EMBL:BC014572 xref: EMBL:BC017564 xref: EMBL:BC030824 xref: EMBL:BC066963 xref: EMBL:D16481 xref: EMBL:D86850 xref: HGNC:HGNC:4803 xref: UniGene:Hs.534639 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063084 ! ECHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022211 name: EDEM2_human def: "ER degradation-enhancing alpha-mannosidase-like 2 precursor gene" [UniProtKB:Q9BV94] synonym: "C20orf31" EXACT [UniProtKB:Q9BV94] synonym: "C20orf49" EXACT [UniProtKB:Q9BV94] synonym: "UNQ573/PRO1135" EXACT [UniProtKB:Q9BV94] xref: EMBL:AK001645 xref: EMBL:AK023931 xref: EMBL:AL135844 xref: EMBL:AL356652 xref: EMBL:AY358580 xref: EMBL:BC001371 xref: EMBL:BC016184 xref: EMBL:CR457266 xref: HGNC:HGNC:15877 xref: UniGene:Hs.356273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063433 ! EDEM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022212 name: EEA1_human def: "Early endosome antigen 1 gene" [UniProtKB:Q15075] synonym: "ZFYVE2" EXACT [UniProtKB:Q15075] xref: EMBL:L40157 xref: EMBL:X78998 xref: HGNC:HGNC:3185 xref: UniGene:Hs.567367 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063025 ! EEA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022213 name: EEF2_human def: "Elongation factor 2 gene" [UniProtKB:P13639] synonym: "EF2" EXACT [UniProtKB:P13639] xref: EMBL:AY942181 xref: EMBL:BC126259 xref: EMBL:M19997 xref: EMBL:X51466 xref: EMBL:Z11692 xref: HGNC:HGNC:3214 xref: UniGene:Hs.515070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063182 ! EF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022214 name: EIF2B1_human def: "Translation initiation factor eIF-2B subunit alpha gene" [UniProtKB:Q14232] synonym: "EIF2BA" EXACT [UniProtKB:Q14232] xref: EMBL:AC117503 xref: EMBL:BC103763 xref: EMBL:BC104188 xref: EMBL:BC104189 xref: EMBL:CH471054 xref: EMBL:CR456831 xref: EMBL:X95648 xref: HGNC:HGNC:3257 xref: UniGene:Hs.78592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015682 ! EI2BA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022215 name: EIF3M_human def: "Eukaryotic translation initiation factor 3 subunit M gene" [UniProtKB:Q7L2H7] synonym: "GA17" EXACT [UniProtKB:Q7L2H7] synonym: "HFLB5" EXACT [UniProtKB:Q7L2H7] synonym: "PCID1" EXACT [UniProtKB:Q7L2H7] synonym: "PNAS-125" EXACT [UniProtKB:Q7L2H7] xref: EMBL:AF064603 xref: EMBL:AF277183 xref: EMBL:AK222564 xref: EMBL:AY769947 xref: EMBL:BC019103 xref: EMBL:BC051292 xref: EMBL:CH471064 xref: EMBL:CR450300 xref: EMBL:DQ185042 xref: HGNC:HGNC:24460 xref: UniGene:Hs.502244 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063407 ! EIF3M_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022216 name: ELAVL3_human def: "ELAV-like protein 3 gene" [UniProtKB:Q14576] synonym: "HUC" EXACT [UniProtKB:Q14576] synonym: "PLE21" EXACT [UniProtKB:Q14576] xref: EMBL:AY036909 xref: EMBL:BC014144 xref: EMBL:D26158 xref: EMBL:L26405 xref: HGNC:HGNC:3314 xref: UniGene:Hs.1701 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062918 ! ELAV3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022217 name: EMD_human def: "Emerin gene" [UniProtKB:P50402] synonym: "EDMD" EXACT [UniProtKB:P50402] synonym: "STA" EXACT [UniProtKB:P50402] xref: EMBL:BC000738 xref: EMBL:BT007401 xref: EMBL:D64111 xref: EMBL:L44140 xref: EMBL:X82434 xref: EMBL:X86810 xref: HGNC:HGNC:3331 xref: UniGene:Hs.522823 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062869 ! EMD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022218 name: EMID2_human def: "Collagen alpha-1(XXVI) chain precursor gene" [UniProtKB:Q96A83] synonym: "COL26A1" EXACT [UniProtKB:Q96A83] synonym: "EMU2" EXACT [UniProtKB:Q96A83] xref: EMBL:AJ416091 xref: HGNC:HGNC:18038 xref: UniGene:Hs.654854 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063339 ! EMID2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022219 name: ENOX1_human def: "Ecto-NOX disulfide-thiol exchanger 1 gene" [UniProtKB:Q8TC92] synonym: "PIG38" EXACT [UniProtKB:Q8TC92] xref: EMBL:AK000956 xref: EMBL:AL138823 xref: EMBL:AL607148 xref: EMBL:AL627430 xref: EMBL:AY513282 xref: EMBL:BC024178 xref: EMBL:CH471075 xref: EMBL:EF432052 xref: HGNC:HGNC:25474 xref: UniGene:Hs.128258 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062800 ! ENOX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022220 name: ENTPD6_human def: "Ectonucleoside triphosphate diphosphohydrolase 6 gene" [UniProtKB:O75354] synonym: "CD39L2" EXACT [UniProtKB:O75354] synonym: "IL6ST2" EXACT [UniProtKB:O75354] xref: EMBL:AF039916 xref: EMBL:AL035252 xref: EMBL:AY327581 xref: EMBL:BC025980 xref: HGNC:HGNC:3368 xref: UniGene:Hs.500375 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063322 ! ENTP6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022221 name: PROCR_human def: "Endothelial protein C receptor precursor gene" [UniProtKB:Q9UNN8] synonym: "EPCR" EXACT [UniProtKB:Q9UNN8] xref: EMBL:AB026584 xref: EMBL:AF106202 xref: EMBL:AF375468 xref: EMBL:AL356652 xref: EMBL:BC014451 xref: EMBL:CR456948 xref: EMBL:L35545 xref: EMBL:X89079 xref: HGNC:HGNC:9452 xref: UniGene:Hs.647450 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063455 ! EPCR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022222 name: EPN1_human def: "Epsin-1 gene" [UniProtKB:Q9Y6I3] xref: EMBL:AF073727 xref: EMBL:AK022454 xref: EMBL:BC044651 xref: HGNC:HGNC:21604 xref: UniGene:Hs.279953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063381 ! EPN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022223 name: CLINT1_human def: "Clathrin interactor 1 gene" [UniProtKB:Q14677] synonym: "ENTH" EXACT [UniProtKB:Q14677] synonym: "EPN4" EXACT [UniProtKB:Q14677] synonym: "EPNR" EXACT [UniProtKB:Q14677] synonym: "KIAA0171" EXACT [UniProtKB:Q14677] xref: EMBL:AF434813 xref: EMBL:AK092765 xref: EMBL:BC004467 xref: EMBL:BC013091 xref: EMBL:BK000414 xref: EMBL:D79993 xref: HGNC:HGNC:23186 xref: UniGene:Hs.699408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063201 ! EPN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022224 name: ERAP1_human def: "Endoplasmic reticulum aminopeptidase 1 gene" [UniProtKB:Q9NZ08] synonym: "APPILS" EXACT [UniProtKB:Q9NZ08] synonym: "ARTS1" EXACT [UniProtKB:Q9NZ08] synonym: "KIAA0525" EXACT [UniProtKB:Q9NZ08] synonym: "UNQ584/PRO1154" EXACT [UniProtKB:Q9NZ08] xref: EMBL:AB011097 xref: EMBL:AF106037 xref: EMBL:AF183569 xref: EMBL:AF222340 xref: EMBL:AY028806 xref: EMBL:AY028807 xref: EMBL:AY358590 xref: EMBL:BC030775 xref: HGNC:HGNC:18173 xref: UniGene:Hs.436186 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062994 ! ERAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022225 name: MVD_human def: "Diphosphomevalonate decarboxylase gene" [UniProtKB:P53602] synonym: "MPD" EXACT [UniProtKB:P53602] xref: EMBL:BC000011 xref: EMBL:BT006930 xref: EMBL:CH471184 xref: EMBL:U49260 xref: HGNC:HGNC:7529 xref: UniGene:Hs.252457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025709 ! ERG19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022226 name: SC4MOL_human def: "C-4 methylsterol oxidase gene" [UniProtKB:Q15800] synonym: "DESP4" EXACT [UniProtKB:Q15800] synonym: "ERG25" EXACT [UniProtKB:Q15800] xref: EMBL:BC010653 xref: EMBL:BC107879 xref: EMBL:U60205 xref: EMBL:U93162 xref: HGNC:HGNC:10545 xref: UniGene:Hs.105269 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063334 ! ERG25_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022227 name: ERLIN1_human def: "Erlin-1 gene" [UniProtKB:O75477] synonym: "C10orf69" EXACT [UniProtKB:O75477] synonym: "KE04" EXACT [UniProtKB:O75477] synonym: "KEO4" EXACT [UniProtKB:O75477] synonym: "SPFH1" EXACT [UniProtKB:O75477] xref: EMBL:AF064093 xref: EMBL:AK222480 xref: EMBL:AL138921 xref: EMBL:BC031791 xref: EMBL:CH471066 xref: HGNC:HGNC:16947 xref: UniGene:Hs.150087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063132 ! ERLN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022228 name: FAM62A_human def: "Extended synaptotagmin-1 gene" [UniProtKB:Q9BSJ8] synonym: "ESYT1" EXACT [UniProtKB:Q9BSJ8] synonym: "KIAA0747" EXACT [UniProtKB:Q9BSJ8] synonym: "MBC2" EXACT [UniProtKB:Q9BSJ8] xref: EMBL:AB018290 xref: EMBL:AK025463 xref: EMBL:AK025878 xref: EMBL:AK290337 xref: EMBL:AL050134 xref: EMBL:BC004998 xref: EMBL:CH471054 xref: EMBL:DQ993200 xref: HGNC:HGNC:29534 xref: UniGene:Hs.632729 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063068 ! ESYT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022229 name: EXOC2_human def: "Exocyst complex component 2 gene" [UniProtKB:Q96KP1] synonym: "SEC5" EXACT [UniProtKB:Q96KP1] synonym: "SEC5L1" EXACT [UniProtKB:Q96KP1] xref: EMBL:AJ414403 xref: EMBL:AK001888 xref: EMBL:AL031770 xref: EMBL:AL512308 xref: EMBL:AL833213 xref: EMBL:BC016918 xref: EMBL:BC080542 xref: HGNC:HGNC:24968 xref: UniGene:Hs.484412 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063296 ! EXOC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022230 name: EXOC4_human def: "Exocyst complex component 4 gene" [UniProtKB:Q96A65] synonym: "KIAA1699" EXACT [UniProtKB:Q96A65] synonym: "SEC8" EXACT [UniProtKB:Q96A65] synonym: "SEC8L1" EXACT [UniProtKB:Q96A65] xref: EMBL:AB051486 xref: EMBL:AF132734 xref: EMBL:AF380839 xref: EMBL:AK022751 xref: EMBL:AK027688 xref: EMBL:AL834475 xref: HGNC:HGNC:30389 xref: UniGene:Hs.321273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063049 ! EXOC4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022231 name: EXOC7_human def: "Exocyst complex component 7 gene" [UniProtKB:Q9UPT5] synonym: "EXO70" EXACT [UniProtKB:Q9UPT5] synonym: "KIAA1067" EXACT [UniProtKB:Q9UPT5] xref: EMBL:AB028990 xref: EMBL:AK022397 xref: EMBL:AK022552 xref: EMBL:AK023832 xref: EMBL:AL834324 xref: EMBL:BC011045 xref: EMBL:BC018466 xref: HGNC:HGNC:23214 xref: UniGene:Hs.449585 xref: UniGene:Hs.533985 xref: UniGene:Hs.551925 xref: UniGene:Hs.633454 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062769 ! EXOC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022232 name: FAM100A_human def: "Protein FAM100A gene" [UniProtKB:Q8TB05] synonym: "PP11303" EXACT [UniProtKB:Q8TB05] xref: EMBL:AF447881 xref: EMBL:BC012018 xref: EMBL:BC025327 xref: EMBL:BC062534 xref: HGNC:HGNC:29576 xref: UniGene:Hs.513313 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063515 ! F100A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022233 name: FAM101B_human def: "Protein FAM101B gene" [UniProtKB:Q8N5W9] xref: EMBL:BC031341 xref: HGNC:HGNC:28705 xref: UniGene:Hs.345588 xref: UniGene:Hs.591203 xref: UniGene:Hs.596411 xref: UniGene:Hs.615223 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063472 ! F101B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022234 name: FAM103A1_human def: "Protein FAM103A1 gene" [UniProtKB:Q9BTL3] synonym: "C15orf18" EXACT [UniProtKB:Q9BTL3] xref: EMBL:BC003627 xref: EMBL:BC027181 xref: EMBL:BC112329 xref: HGNC:HGNC:31022 xref: UniGene:Hs.80624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062856 ! F103A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022235 name: FAM105B_human def: "Protein FAM105B gene" [UniProtKB:Q96BN8] xref: EMBL:AK092203 xref: EMBL:BC007706 xref: EMBL:BC015392 xref: HGNC:HGNC:25118 xref: UniGene:Hs.406335 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062939 ! F105B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022236 name: ST13_human def: "Hsc70-interacting protein gene" [UniProtKB:P50502] synonym: "FAM10A1" EXACT [UniProtKB:P50502] synonym: "HIP" EXACT [UniProtKB:P50502] synonym: "SNC6" EXACT [UniProtKB:P50502] xref: EMBL:BC052982 xref: EMBL:BC071629 xref: EMBL:CR456586 xref: EMBL:U17714 xref: EMBL:U28918 xref: EMBL:Z98048 xref: HGNC:HGNC:11343 xref: UniGene:Hs.701994 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063106 ! F10A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022237 name: FAM10A4_human def: "Protein FAM10A4 gene" [UniProtKB:Q8IZP2] xref: EMBL:AF539468 xref: HGNC:HGNC:18487 xref: UniGene:Hs.511834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063115 ! F10A4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022238 name: FRA10AC1_human def: "Protein FRA10AC1 gene" [UniProtKB:Q70Z53] synonym: "C10orf4" EXACT [UniProtKB:Q70Z53] synonym: "PRO2972" EXACT [UniProtKB:Q70Z53] xref: EMBL:AF305826 xref: EMBL:AJ431721 xref: EMBL:AJ431722 xref: EMBL:AJ431723 xref: EMBL:AJ431724 xref: EMBL:AJ431725 xref: EMBL:AK090955 xref: EMBL:AL157396 xref: EMBL:BC018007 xref: HGNC:HGNC:1162 xref: UniGene:Hs.658192 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063348 ! F10C1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022239 name: FAM120A_human def: "Constitutive coactivator of PPAR-gamma-like protein 1 gene" [UniProtKB:Q9NZB2] synonym: "C9orf10" EXACT [UniProtKB:Q9NZB2] synonym: "KIAA0183" EXACT [UniProtKB:Q9NZB2] xref: EMBL:AF055017 xref: EMBL:AF214737 xref: EMBL:AF214738 xref: EMBL:AL353629 xref: EMBL:BC007879 xref: EMBL:BC098584 xref: EMBL:BC111736 xref: EMBL:D80005 xref: HGNC:HGNC:13247 xref: UniGene:Hs.372003 xref: UniGene:Hs.703219 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062987 ! F120A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022240 name: FAM134A_human def: "Protein FAM134A gene" [UniProtKB:Q8NC44] synonym: "C2orf17" EXACT [UniProtKB:Q8NC44] xref: EMBL:AC068946 xref: EMBL:AK074983 xref: EMBL:AL136758 xref: EMBL:BC064950 xref: HGNC:HGNC:28450 xref: UniGene:Hs.516707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063379 ! F134A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022241 name: FAM176A_human def: "Protein FAM176A gene" [UniProtKB:Q9H8M9] synonym: "SP24" EXACT [UniProtKB:Q9H8M9] synonym: "TMEM166" EXACT [UniProtKB:Q9H8M9] xref: EMBL:AC007099 xref: EMBL:AF177337 xref: EMBL:AK023453 xref: EMBL:BC016157 xref: EMBL:BC063016 xref: EMBL:CR457314 xref: HGNC:HGNC:25816 xref: UniGene:Hs.302346 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063411 ! F176A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022242 name: F10_human def: "Coagulation factor X precursor gene" [UniProtKB:P00742] xref: EMBL:AF503510 xref: EMBL:BC046125 xref: EMBL:K01886 xref: EMBL:K03194 xref: EMBL:L00390 xref: EMBL:L00391 xref: EMBL:L00392 xref: EMBL:L00393 xref: EMBL:L00394 xref: EMBL:L00395 xref: EMBL:L00396 xref: EMBL:L29433 xref: EMBL:M22613 xref: EMBL:M33297 xref: EMBL:M57285 xref: HGNC:HGNC:3528 xref: UniGene:Hs.361463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063456 ! FA10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022243 name: FAM21C_human def: "Protein FAM21C gene" [UniProtKB:Q9Y4E1] synonym: "KIAA0592" EXACT [UniProtKB:Q9Y4E1] xref: EMBL:AB011164 xref: EMBL:AC012044 xref: EMBL:AL050279 xref: EMBL:AL645998 xref: EMBL:AL731535 xref: EMBL:BC006456 xref: HGNC:HGNC:23414 xref: UniGene:Hs.365286 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029890 ! FA21C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022244 name: FAM46A_human def: "Protein FAM46A gene" [UniProtKB:Q96IP4] synonym: "C6orf37" EXACT [UniProtKB:Q96IP4] synonym: "XTP11" EXACT [UniProtKB:Q96IP4] xref: EMBL:AF350451 xref: EMBL:AK000044 xref: EMBL:AK056057 xref: EMBL:AK292109 xref: EMBL:AL078599 xref: EMBL:AY740520 xref: EMBL:BC000683 xref: EMBL:BC007351 xref: EMBL:CH471051 xref: HGNC:HGNC:18345 xref: UniGene:Hs.10784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063215 ! FA46A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022245 name: FAM46B_human def: "Protein FAM46B gene" [UniProtKB:Q96A09] xref: EMBL:AL356390 xref: EMBL:BC012790 xref: EMBL:BC014160 xref: HGNC:HGNC:28273 xref: UniGene:Hs.632378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062965 ! FA46B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022246 name: FAM48A_human def: "Protein FAM48A gene" [UniProtKB:Q8NEM7] synonym: "C13orf19" EXACT [UniProtKB:Q8NEM7] synonym: "FP757" EXACT [UniProtKB:Q8NEM7] xref: EMBL:AF093250 xref: EMBL:AF370384 xref: EMBL:AJ130894 xref: EMBL:AL138706 xref: EMBL:AL391383 xref: EMBL:BC030686 xref: HGNC:HGNC:20596 xref: UniGene:Hs.435815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063193 ! FA48A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022247 name: FAM71C_human def: "Protein FAM71C gene" [UniProtKB:Q8NEG0] xref: EMBL:BC031221 xref: HGNC:HGNC:28594 xref: UniGene:Hs.591011 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062966 ! FA71C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022248 name: F7_human def: "Coagulation factor VII precursor gene" [UniProtKB:P08709] xref: EMBL:AF466933 xref: EMBL:AL137002 xref: EMBL:AY212252 xref: EMBL:DQ142911 xref: EMBL:J02933 xref: EMBL:M13232 xref: HGNC:HGNC:3544 xref: UniGene:Hs.36989 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063069 ! FA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022249 name: FAM96A_human def: "UPF0195 protein FAM96A gene" [UniProtKB:Q9H5X1] xref: EMBL:AK026528 xref: EMBL:BC008865 xref: HGNC:HGNC:26235 xref: UniGene:Hs.439548 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062967 ! FA96A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022250 name: FASN_human def: "Fatty acid synthase gene" [UniProtKB:P49327] synonym: "FAS" EXACT [UniProtKB:P49327] xref: EMBL:AY451392 xref: EMBL:BC007267 xref: EMBL:BC007909 xref: EMBL:BC014634 xref: EMBL:BC063242 xref: EMBL:S80437 xref: EMBL:U26644 xref: EMBL:U29344 xref: HGNC:HGNC:3594 xref: UniGene:Hs.83190 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062802 ! FAS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022251 name: FAT_human def: "Protocadherin Fat 1 precursor gene" [UniProtKB:Q14517] synonym: "CDHF7" EXACT [UniProtKB:Q14517] xref: EMBL:X87241 xref: HGNC:HGNC:3595 xref: UniGene:Hs.481371 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062991 ! FAT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022252 name: FATE1_human def: "Fetal and adult testis-expressed transcript protein gene" [UniProtKB:Q969F0] synonym: "FATE" EXACT [UniProtKB:Q969F0] xref: EMBL:AF249872 xref: EMBL:AK057369 xref: EMBL:AY101182 xref: EMBL:BC022064 xref: HGNC:HGNC:24683 xref: UniGene:Hs.301960 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062910 ! FATE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022253 name: FBXO28_human def: "F-box only protein 28 gene" [UniProtKB:Q9NVF7] synonym: "KIAA0483" EXACT [UniProtKB:Q9NVF7] xref: EMBL:AB007952 xref: EMBL:AK001628 xref: EMBL:AL390122 xref: EMBL:BC031576 xref: HGNC:HGNC:29046 xref: UniGene:Hs.64691 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062771 ! FBX28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022254 name: FEV_human def: "Protein FEV gene" [UniProtKB:Q99581] synonym: "PET1" EXACT [UniProtKB:Q99581] xref: EMBL:AC097468 xref: EMBL:BC023511 xref: EMBL:CH471063 xref: EMBL:Y08976 xref: HGNC:HGNC:18562 xref: UniGene:Hs.234759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058427 ! FEV_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022255 name: FKBP5_human def: "FK506-binding protein 5 gene" [UniProtKB:Q13451] synonym: "AIG6" EXACT [UniProtKB:Q13451] synonym: "FKBP51" EXACT [UniProtKB:Q13451] xref: EMBL:AF194172 xref: EMBL:BC042605 xref: EMBL:U42031 xref: EMBL:U71321 xref: HGNC:HGNC:3721 xref: UniGene:Hs.407190 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063039 ! FKBP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022256 name: FLOT1_human def: "Flotillin-1 gene" [UniProtKB:O75955] xref: EMBL:AF085357 xref: EMBL:AF089750 xref: EMBL:AF117234 xref: EMBL:BA000025 xref: EMBL:BC001146 xref: HGNC:HGNC:3757 xref: UniGene:Hs.179986 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062976 ! FLOT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022257 name: FLOT2_human def: "Flotillin-2 gene" [UniProtKB:Q14254] synonym: "ESA1" EXACT [UniProtKB:Q14254] synonym: "M17S1" EXACT [UniProtKB:Q14254] xref: EMBL:BC017292 xref: EMBL:BT019478 xref: EMBL:M60922 xref: HGNC:HGNC:3758 xref: UniGene:Hs.514038 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062977 ! FLOT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022258 name: FMNL1_human def: "Formin-like protein 1 gene" [UniProtKB:O95466] synonym: "C17orf1" EXACT [UniProtKB:O95466] synonym: "C17orf1B" EXACT [UniProtKB:O95466] synonym: "FMNL" EXACT [UniProtKB:O95466] xref: EMBL:AF432213 xref: EMBL:AJ008112 xref: EMBL:AY278319 xref: EMBL:BC001710 xref: EMBL:BC009000 xref: EMBL:BC021906 xref: EMBL:BC073988 xref: EMBL:CR456759 xref: HGNC:HGNC:1212 xref: UniGene:Hs.100217 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063463 ! FMNL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022259 name: FN3K_human def: "Fructosamine-3-kinase gene" [UniProtKB:Q9H479] xref: EMBL:AJ404615 xref: EMBL:BC042680 xref: HGNC:HGNC:24822 xref: UniGene:Hs.151135 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063226 ! FN3K_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022260 name: FDPS_human def: "Farnesyl pyrophosphate synthetase gene" [UniProtKB:P14324] synonym: "FPS" EXACT [UniProtKB:P14324] synonym: "KIAA1293" EXACT [UniProtKB:P14324] xref: EMBL:AK291084 xref: EMBL:AL139410 xref: EMBL:BC010004 xref: EMBL:CH471121 xref: EMBL:D14697 xref: EMBL:J05262 xref: EMBL:M29863 xref: HGNC:HGNC:3631 xref: UniGene:Hs.335918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063308 ! FPPS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022261 name: FXN_human def: "Frataxin, mitochondrial precursor gene" [UniProtKB:Q16595] synonym: "FRDA" EXACT [UniProtKB:Q16595] synonym: "X25" EXACT [UniProtKB:Q16595] xref: EMBL:AF028240 xref: EMBL:AL162730 xref: EMBL:BC023633 xref: EMBL:BC048097 xref: EMBL:U43747 xref: EMBL:U43748 xref: EMBL:U43749 xref: EMBL:U43750 xref: EMBL:U43751 xref: EMBL:U43752 xref: EMBL:U43753 xref: EMBL:U93173 xref: EMBL:Y13751 xref: HGNC:HGNC:3951 xref: UniGene:Hs.29978 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032300 ! FRDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022262 name: FUNDC2_human def: "FUN14 domain-containing protein 2 gene" [UniProtKB:Q9BWH2] synonym: "DC44" EXACT [UniProtKB:Q9BWH2] synonym: "HCBP6" EXACT [UniProtKB:Q9BWH2] synonym: "HCC3" EXACT [UniProtKB:Q9BWH2] synonym: "PD03104" EXACT [UniProtKB:Q9BWH2] xref: EMBL:AF267862 xref: EMBL:AF320778 xref: EMBL:AJ272054 xref: EMBL:AY032594 xref: EMBL:BC000255 xref: EMBL:BC072685 xref: EMBL:BC108657 xref: EMBL:BX470111 xref: EMBL:CH471172 xref: HGNC:HGNC:24925 xref: UniGene:Hs.356050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063393 ! FUND2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022263 name: FUS_human def: "RNA-binding protein FUS gene" [UniProtKB:P35637] synonym: "TLS" EXACT [UniProtKB:P35637] xref: EMBL:AF071213 xref: EMBL:BC000402 xref: EMBL:BC002459 xref: EMBL:S62138 xref: EMBL:S62140 xref: EMBL:X71427 xref: EMBL:X71428 xref: HGNC:HGNC:4010 xref: UniGene:Hs.513522 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063414 ! FUS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022264 name: FUZ_human def: "Protein fuzzy homolog gene" [UniProtKB:Q9BT04] synonym: "FY" EXACT [UniProtKB:Q9BT04] xref: EMBL:AK026341 xref: EMBL:BC004445 xref: EMBL:BC010092 xref: EMBL:BC016793 xref: EMBL:CH471177 xref: HGNC:HGNC:26219 xref: UniGene:Hs.288800 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062931 ! FUZZY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022265 name: FXYD3_human def: "FXYD domain-containing ion transport regulator 3 precursor gene" [UniProtKB:Q14802] synonym: "MAT8" EXACT [UniProtKB:Q14802] synonym: "PLML" EXACT [UniProtKB:Q14802] xref: EMBL:AC020907 xref: EMBL:BC005238 xref: EMBL:BC090044 xref: EMBL:BT006712 xref: EMBL:CR456945 xref: EMBL:CR542197 xref: EMBL:U28249 xref: EMBL:X93036 xref: HGNC:HGNC:4027 xref: UniGene:Hs.301350 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063478 ! FXYD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022266 name: C6orf48_human def: "Protein G8 gene" [UniProtKB:Q9UBA6] synonym: "G8" EXACT [UniProtKB:Q9UBA6] xref: EMBL:AJ249731 xref: EMBL:AJ249732 xref: HGNC:HGNC:19078 xref: UniGene:Hs.640836 xref: UniGene:Hs.654301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063287 ! G8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022267 name: GAN_human def: "Gigaxonin gene" [UniProtKB:Q9H2C0] synonym: "GAN1" EXACT [UniProtKB:Q9H2C0] synonym: "KLHL16" EXACT [UniProtKB:Q9H2C0] xref: EMBL:AF291673 xref: EMBL:BC044840 xref: HGNC:HGNC:4137 xref: UniGene:Hs.112569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063005 ! GAN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022268 name: GBP2_human def: "Interferon-induced guanylate-binding protein 2 gene" [UniProtKB:P32456] xref: EMBL:AL832451 xref: EMBL:M55543 xref: HGNC:HGNC:4183 xref: UniGene:Hs.386567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031499 ! GBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022269 name: GCKR_human def: "Glucokinase regulatory protein gene" [UniProtKB:Q14397] xref: EMBL:AC074117 xref: EMBL:AY320034 xref: EMBL:Y09592 xref: EMBL:Y09593 xref: EMBL:Z48475 xref: HGNC:HGNC:4196 xref: UniGene:Hs.89771 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063245 ! GCKR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022270 name: GCSH_human def: "Glycine cleavage system H protein, mitochondrial precursor gene" [UniProtKB:P23434] xref: EMBL:AY310735 xref: EMBL:BC000790 xref: EMBL:BC020922 xref: EMBL:D00723 xref: EMBL:M69175 xref: HGNC:HGNC:4208 xref: UniGene:Hs.546256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062899 ! GCSH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022271 name: SIP1_human def: "Survival of motor neuron protein-interacting protein 1 gene" [UniProtKB:O14893] synonym: "GEMIN2" EXACT [UniProtKB:O14893] xref: EMBL:AB037701 xref: EMBL:AB037702 xref: EMBL:AB037703 xref: EMBL:AF027150 xref: EMBL:AJ250932 xref: EMBL:AJ250933 xref: EMBL:AJ250934 xref: EMBL:AJ250935 xref: EMBL:AJ250936 xref: EMBL:AJ250937 xref: EMBL:AJ250938 xref: EMBL:AJ250939 xref: EMBL:BC104968 xref: HGNC:HGNC:10884 xref: UniGene:Hs.652307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063282 ! GEMI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022272 name: GEMIN4_human def: "Component of gems 4 gene" [UniProtKB:P57678] xref: EMBL:AF173856 xref: EMBL:AL080150 xref: EMBL:AL080167 xref: HGNC:HGNC:15717 xref: UniGene:Hs.499620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063087 ! GEMI4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022273 name: GEMIN5_human def: "Gem-associated protein 5 gene" [UniProtKB:Q8TEQ6] xref: EMBL:AK022748 xref: EMBL:AK074066 xref: EMBL:AL117665 xref: EMBL:AY063750 xref: EMBL:BC008776 xref: EMBL:BC014147 xref: EMBL:BC113614 xref: HGNC:HGNC:20043 xref: UniGene:Hs.483921 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062979 ! GEMI5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022274 name: GEMIN7_human def: "Gem-associated protein 7 gene" [UniProtKB:Q9H840] xref: EMBL:AK024018 xref: EMBL:AY114106 xref: EMBL:BC007793 xref: HGNC:HGNC:20045 xref: UniGene:Hs.466919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063415 ! GEMI7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022275 name: GFAP_human def: "Glial fibrillary acidic protein gene" [UniProtKB:P14136] xref: EMBL:AF419299 xref: EMBL:AJ306447 xref: EMBL:AK128790 xref: EMBL:AK222683 xref: EMBL:AL133013 xref: EMBL:AY142187 xref: EMBL:AY142188 xref: EMBL:AY142191 xref: EMBL:BC013596 xref: EMBL:BC041765 xref: EMBL:BC062609 xref: EMBL:J04569 xref: EMBL:M26638 xref: EMBL:S40719 xref: HGNC:HGNC:4235 xref: UniGene:Hs.514227 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062814 ! GFAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022276 name: GCHFR_human def: "GTP cyclohydrolase 1 feedback regulatory protein gene" [UniProtKB:P30047] synonym: "GFRP" EXACT [UniProtKB:P30047] xref: EMBL:BC112262 xref: EMBL:BC112264 xref: EMBL:U78190 xref: HGNC:HGNC:4194 xref: UniGene:Hs.631717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063263 ! GFRP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022277 name: GHR_human def: "Growth hormone receptor precursor gene" [UniProtKB:P10912] xref: EMBL:AJ278681 xref: EMBL:M28458 xref: EMBL:M28459 xref: EMBL:M28460 xref: EMBL:M28461 xref: EMBL:M28462 xref: EMBL:M28463 xref: EMBL:M28464 xref: EMBL:M28465 xref: EMBL:M28466 xref: EMBL:X06562 xref: HGNC:HGNC:4263 xref: UniGene:Hs.125180 xref: UniGene:Hs.684631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063273 ! GHR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022278 name: GLRX3_human def: "Glutaredoxin-3 gene" [UniProtKB:O76003] synonym: "HUSSY-22" EXACT [UniProtKB:O76003] synonym: "PICOT" EXACT [UniProtKB:O76003] synonym: "TXNL2" EXACT [UniProtKB:O76003] xref: EMBL:AF118649 xref: EMBL:AF118652 xref: EMBL:AJ010841 xref: EMBL:AK021926 xref: EMBL:AK022131 xref: EMBL:AL139123 xref: EMBL:BC005289 xref: EMBL:BC014372 xref: EMBL:CH471066 xref: HGNC:HGNC:15987 xref: UniGene:Hs.42644 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062932 ! GLRX3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022279 name: SHMT2_human def: "Serine hydroxymethyltransferase, mitochondrial precursor gene" [UniProtKB:P34897] xref: EMBL:BC011911 xref: EMBL:BC013677 xref: EMBL:BC044211 xref: EMBL:BT006866 xref: EMBL:L11932 xref: EMBL:U23143 xref: EMBL:Y12331 xref: HGNC:HGNC:10852 xref: UniGene:Hs.75069 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063361 ! GLYM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022280 name: GMFB_human def: "Glia maturation factor beta gene" [UniProtKB:P60983] xref: EMBL:AB001106 xref: EMBL:CR542113 xref: EMBL:M86492 xref: HGNC:HGNC:4373 xref: UniGene:Hs.151413 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063366 ! GMFB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022281 name: GNL3L_human def: "Guanine nucleotide-binding protein-like 3-like protein gene" [UniProtKB:Q9NVN8] xref: EMBL:AK001475 xref: EMBL:AL391139 xref: EMBL:BC011720 xref: HGNC:HGNC:25553 xref: UniGene:Hs.654677 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062853 ! GNL3L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022282 name: GNMT_human def: "Glycine N-methyltransferase gene" [UniProtKB:Q14749] xref: EMBL:AF101475 xref: EMBL:AF101477 xref: EMBL:BC032627 xref: EMBL:X62250 xref: HGNC:HGNC:4415 xref: UniGene:Hs.144914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062843 ! GNMT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022283 name: GNPDA1_human def: "Glucosamine-6-phosphate isomerase 1 gene" [UniProtKB:P46926] synonym: "GNPI" EXACT [UniProtKB:P46926] synonym: "HLN" EXACT [UniProtKB:P46926] synonym: "KIAA0060" EXACT [UniProtKB:P46926] xref: EMBL:AC005740 xref: EMBL:AF029914 xref: EMBL:AF035804 xref: EMBL:AF035805 xref: EMBL:AF035806 xref: EMBL:AF035807 xref: EMBL:AF035808 xref: EMBL:AF035809 xref: EMBL:AF048826 xref: EMBL:AJ002231 xref: EMBL:BC012853 xref: EMBL:BC020769 xref: EMBL:BC022322 xref: EMBL:D31766 xref: HGNC:HGNC:4417 xref: UniGene:Hs.633853 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062913 ! GNPI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022284 name: RNF130_human def: "Goliath homolog precursor gene" [UniProtKB:Q86XS8] xref: EMBL:AF155650 xref: EMBL:AY083998 xref: EMBL:BC017100 xref: EMBL:BC065244 xref: EMBL:BC082267 xref: EMBL:BC108306 xref: HGNC:HGNC:18280 xref: UniGene:Hs.484363 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063459 ! GOLI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022285 name: GOPC_human def: "Golgi-associated PDZ and coiled-coil motif-containing protein gene" [UniProtKB:Q9HD26] synonym: "CAL" EXACT [UniProtKB:Q9HD26] synonym: "FIG" EXACT [UniProtKB:Q9HD26] xref: EMBL:AB209385 xref: EMBL:AF287894 xref: EMBL:AF450008 xref: EMBL:AL589939 xref: EMBL:AY033606 xref: EMBL:BC009553 xref: EMBL:CH471051 xref: EMBL:Z85999 xref: HGNC:HGNC:17643 xref: UniGene:Hs.191539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063033 ! GOPC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022286 name: GPR183_human def: "G-protein coupled receptor 183 gene" [UniProtKB:P32249] synonym: "EBI2" EXACT [UniProtKB:P32249] xref: EMBL:AK223390 xref: EMBL:AK292091 xref: EMBL:AK313443 xref: EMBL:AL160155 xref: EMBL:BC020752 xref: EMBL:CH471085 xref: EMBL:L08177 xref: HGNC:HGNC:3128 xref: UniGene:Hs.784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063406 ! GP183_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022287 name: GPN1_human def: "GPN-loop GTPase 1 gene" [UniProtKB:Q9HCN4] synonym: "HUSSY-23" EXACT [UniProtKB:Q9HCN4] synonym: "MBDIN" EXACT [UniProtKB:Q9HCN4] synonym: "XAB1" EXACT [UniProtKB:Q9HCN4] xref: EMBL:AB044661 xref: EMBL:AJ010842 xref: EMBL:BC007451 xref: HGNC:HGNC:17030 xref: UniGene:Hs.18259 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058813 ! GPN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022288 name: GPATCH8_human def: "G patch domain-containing protein 8 gene" [UniProtKB:Q9UKJ3] synonym: "GPATC8" EXACT [UniProtKB:Q9UKJ3] synonym: "KIAA0553" EXACT [UniProtKB:Q9UKJ3] xref: EMBL:AB011125 xref: EMBL:AF160252 xref: HGNC:HGNC:29066 xref: UniGene:Hs.463129 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063309 ! GPTC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022289 name: GREM1_human def: "Gremlin-1 precursor gene" [UniProtKB:O60565] synonym: "CKTSF1B1" EXACT [UniProtKB:O60565] synonym: "DAND2" EXACT [UniProtKB:O60565] synonym: "DRM" EXACT [UniProtKB:O60565] synonym: "PIG2" EXACT [UniProtKB:O60565] xref: EMBL:AB032372 xref: EMBL:AF045800 xref: EMBL:AF110137 xref: EMBL:AF154054 xref: EMBL:AK095741 xref: EMBL:AK095890 xref: EMBL:AY232290 xref: EMBL:BC069525 xref: EMBL:BC093778 xref: EMBL:BC101611 xref: HGNC:HGNC:2001 xref: UniGene:Hs.40098 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063191 ! GREM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022290 name: GLG1_human def: "Golgi apparatus protein 1 precursor gene" [UniProtKB:Q92896] synonym: "CFR1" EXACT [UniProtKB:Q92896] synonym: "ESL1" EXACT [UniProtKB:Q92896] synonym: "MG160" EXACT [UniProtKB:Q92896] xref: EMBL:U28811 xref: EMBL:U64791 xref: HGNC:HGNC:4316 xref: UniGene:Hs.201712 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063139 ! GSLG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022291 name: GYS1_human def: "Glycogen [starch] synthase, muscle gene" [UniProtKB:P13807] synonym: "GYS" EXACT [UniProtKB:P13807] xref: EMBL:BC002617 xref: EMBL:BC007688 xref: EMBL:J04501 xref: EMBL:U32573 xref: EMBL:Z33609 xref: EMBL:Z33610 xref: EMBL:Z33622 xref: EMBL:Z33623 xref: EMBL:Z33624 xref: EMBL:Z33625 xref: EMBL:Z33626 xref: EMBL:Z33627 xref: EMBL:Z33628 xref: EMBL:Z33629 xref: EMBL:Z33630 xref: EMBL:Z33631 xref: EMBL:Z33633 xref: HGNC:HGNC:4706 xref: UniGene:Hs.386225 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063284 ! GYS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022292 name: HIST1H1C_human def: "Histone H1.2 gene" [UniProtKB:P16403] synonym: "H1F2" EXACT [UniProtKB:P16403] xref: EMBL:AF531300 xref: EMBL:BC002649 xref: EMBL:X57129 xref: HGNC:HGNC:4716 xref: UniGene:Hs.7644 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063188 ! H12_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022293 name: H1FX_human def: "Histone H1x gene" [UniProtKB:Q92522] xref: EMBL:BC000426 xref: EMBL:BC010435 xref: EMBL:D64142 xref: HGNC:HGNC:4722 xref: UniGene:Hs.75307 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063190 ! H1X_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022294 name: HIST1H2AC_human def: "Histone H2A type 1-C gene" [UniProtKB:Q93077] synonym: "H2AFL" EXACT [UniProtKB:Q93077] xref: EMBL:AY131984 xref: EMBL:BC017379 xref: EMBL:BC050602 xref: EMBL:BC085010 xref: EMBL:U90551 xref: EMBL:U91328 xref: EMBL:Z80778 xref: HGNC:HGNC:4733 xref: UniGene:Hs.484950 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021917 ! H2A1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022295 name: HIST2H2AA3_human def: "Histone H2A type 2-A gene" [UniProtKB:Q6FI13] synonym: "H2AFO" EXACT [UniProtKB:Q6FI13] synonym: "HIST2H2AA" EXACT [UniProtKB:Q6FI13] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021914 ! H2A2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022296 name: HIST2H2AA4_human def: "Histone H2A type 2-A gene" [UniProtKB:Q6FI13] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021914 ! H2A2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022297 name: HIST1H2BB_human def: "Histone H2B type 1-B gene" [UniProtKB:P33778] synonym: "H2BFF" EXACT [UniProtKB:P33778] xref: EMBL:AF531285 xref: EMBL:BC096728 xref: EMBL:X57127 xref: HGNC:HGNC:4751 xref: UniGene:Hs.553494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063124 ! H2B1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022298 name: HIST1H2BH_human def: "Histone H2B type 1-H gene" [UniProtKB:Q93079] synonym: "H2BFJ" EXACT [UniProtKB:Q93079] xref: EMBL:AF531291 xref: EMBL:AL031777 xref: EMBL:BC096116 xref: EMBL:BC096117 xref: EMBL:BC096118 xref: EMBL:BC096119 xref: EMBL:Z80781 xref: HGNC:HGNC:4755 xref: UniGene:Hs.247815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063352 ! H2B1H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022299 name: HIST3H3_human def: "Histone H3.1t gene" [UniProtKB:Q16695] synonym: "H3FT" EXACT [UniProtKB:Q16695] xref: EMBL:AF531308 xref: EMBL:AL139288 xref: EMBL:BC069079 xref: EMBL:BC101837 xref: EMBL:BC101839 xref: EMBL:CR542013 xref: EMBL:Z49861 xref: HGNC:HGNC:4778 xref: UniGene:Hs.248171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063017 ! H31T_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022300 name: HAX1_human def: "HCLS1-associated protein X-1 gene" [UniProtKB:O00165] synonym: "HS1BP1" EXACT [UniProtKB:O00165] xref: EMBL:AK290626 xref: EMBL:AL354980 xref: EMBL:BC005240 xref: EMBL:BC014314 xref: EMBL:BC015209 xref: EMBL:BC016730 xref: EMBL:CH471121 xref: EMBL:U68566 xref: HGNC:HGNC:16915 xref: UniGene:Hs.199625 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062934 ! HAX1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022301 name: HBZ_human def: "Hemoglobin subunit zeta gene" [UniProtKB:P02008] synonym: "HBZ2" EXACT [UniProtKB:P02008] xref: EMBL:AE006462 xref: EMBL:BC027892 xref: EMBL:J00182 xref: EMBL:M24173 xref: EMBL:Z84721 xref: HGNC:HGNC:4835 xref: UniGene:Hs.585357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063458 ! HBAZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022302 name: HSD17B10_human def: "3-hydroxyacyl-CoA dehydrogenase type-2 gene" [UniProtKB:Q99714] synonym: "ERAB" EXACT [UniProtKB:Q99714] synonym: "HADH2" EXACT [UniProtKB:Q99714] synonym: "SCHAD" EXACT [UniProtKB:Q99714] synonym: "XH98G2" EXACT [UniProtKB:Q99714] xref: EMBL:AF035555 xref: EMBL:AF037438 xref: EMBL:AF069134 xref: EMBL:AY092415 xref: EMBL:BC000372 xref: EMBL:BC008708 xref: EMBL:U73514 xref: EMBL:U96132 xref: HGNC:HGNC:4800 xref: UniGene:Hs.171280 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063213 ! HCD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022303 name: HDDC3_human def: "HD domain-containing protein 3 gene" [UniProtKB:Q8N4P3] xref: EMBL:AC068831 xref: EMBL:BC033794 xref: HGNC:HGNC:30522 xref: UniGene:Hs.349979 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062925 ! HDDC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022304 name: HEBP2_human def: "Heme-binding protein 2 gene" [UniProtKB:Q9Y5Z4] synonym: "C6orf34" EXACT [UniProtKB:Q9Y5Z4] synonym: "SOUL" EXACT [UniProtKB:Q9Y5Z4] xref: EMBL:AF117616 xref: EMBL:AF411610 xref: EMBL:AL031003 xref: EMBL:AY427823 xref: EMBL:BC008205 xref: EMBL:BC010290 xref: EMBL:BC093037 xref: HGNC:HGNC:15716 xref: UniGene:Hs.486589 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062784 ! HEBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022305 name: HELT_human def: "Hairy and enhancer of split-related protein HELT gene" [UniProtKB:A6NFD8] xref: EMBL:AC093824 xref: EMBL:BC140795 xref: EMBL:CH471056 xref: HGNC:HGNC:33783 xref: UniGene:Hs.531242 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053819 ! HELT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022306 name: HERPUD1_human def: "Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein gene" [UniProtKB:Q15011] synonym: "HERP" EXACT [UniProtKB:Q15011] synonym: "KIAA0025" EXACT [UniProtKB:Q15011] synonym: "MIF1" EXACT [UniProtKB:Q15011] xref: EMBL:AB034989 xref: EMBL:AB034990 xref: EMBL:AF055001 xref: EMBL:AF055003 xref: EMBL:BC000086 xref: EMBL:BC008320 xref: EMBL:BC009739 xref: EMBL:BC032673 xref: EMBL:D14695 xref: HGNC:HGNC:13744 xref: UniGene:Hs.146393 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026851 ! HERP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022307 name: HMGCL_human def: "Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor gene" [UniProtKB:P35914] xref: EMBL:BC010570 xref: EMBL:L07033 xref: EMBL:U49712 xref: EMBL:U49713 xref: EMBL:U49714 xref: EMBL:U49715 xref: EMBL:U49716 xref: EMBL:U49717 xref: EMBL:U49718 xref: EMBL:U49719 xref: HGNC:HGNC:5005 xref: UniGene:Hs.533444 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063475 ! HMGCL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022308 name: HN1L_human def: "Hematological and neurological expressed 1-like protein gene" [UniProtKB:Q9H910] synonym: "C16orf34" EXACT [UniProtKB:Q9H910] synonym: "L11" EXACT [UniProtKB:Q9H910] xref: EMBL:AE006639 xref: EMBL:AK023154 xref: EMBL:AY323831 xref: EMBL:AY323978 xref: EMBL:AY323979 xref: EMBL:AY598330 xref: EMBL:BC014438 xref: EMBL:BC060853 xref: HGNC:HGNC:14137 xref: UniGene:Hs.513261 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063499 ! HN1L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022309 name: HNRNPH2_human def: "Heterogeneous nuclear ribonucleoprotein H2 gene" [UniProtKB:P55795] synonym: "FTP3" EXACT [UniProtKB:P55795] synonym: "HNRPH2" EXACT [UniProtKB:P55795] xref: EMBL:AL035422 xref: EMBL:U01923 xref: EMBL:U78027 xref: HGNC:HGNC:5042 xref: UniGene:Hs.632828 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063355 ! HNRH2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022310 name: HNRNPM_human def: "Heterogeneous nuclear ribonucleoprotein M gene" [UniProtKB:P52272] synonym: "HNRPM" EXACT [UniProtKB:P52272] synonym: "NAGR1" EXACT [UniProtKB:P52272] xref: EMBL:AF061832 xref: EMBL:BC000138 xref: EMBL:BC008895 xref: EMBL:BC019580 xref: EMBL:L03532 xref: EMBL:L32611 xref: HGNC:HGNC:5046 xref: UniGene:Hs.465808 xref: UniGene:Hs.666214 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062955 ! HNRPM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022311 name: HNRNPR_human def: "Heterogeneous nuclear ribonucleoprotein R gene" [UniProtKB:O43390] synonym: "HNRPR" EXACT [UniProtKB:O43390] xref: EMBL:AF000364 xref: EMBL:AL109936 xref: HGNC:HGNC:5047 xref: UniGene:Hs.373763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063382 ! HNRPR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022312 name: HNRNPU_human def: "Heterogeneous nuclear ribonucleoprotein U gene" [UniProtKB:Q00839] synonym: "HNRPU" EXACT [UniProtKB:Q00839] synonym: "SAFA" EXACT [UniProtKB:Q00839] synonym: "U21.1" EXACT [UniProtKB:Q00839] xref: EMBL:AF068846 xref: EMBL:BC003367 xref: EMBL:BC003621 xref: EMBL:BC007950 xref: EMBL:BC024767 xref: EMBL:BC034925 xref: EMBL:BX323046 xref: EMBL:X65488 xref: HGNC:HGNC:5048 xref: UniGene:Hs.166463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063051 ! HNRPU_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022313 name: HOOK2_human def: "Protein Hook homolog 2 gene" [UniProtKB:Q96ED9] xref: EMBL:AF044924 xref: EMBL:BC012443 xref: HGNC:HGNC:19885 xref: UniGene:Hs.30792 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062809 ! HOOK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022314 name: HPCAL1_human def: "Hippocalcin-like protein 1 gene" [UniProtKB:P37235] synonym: "BDR1" EXACT [UniProtKB:P37235] xref: EMBL:BC009846 xref: EMBL:BC017028 xref: EMBL:BC017482 xref: EMBL:D16227 xref: HGNC:HGNC:5145 xref: UniGene:Hs.467696 xref: UniGene:Hs.580427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062908 ! HPCL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022315 name: HPCAL4_human def: "Hippocalcin-like protein 4 gene" [UniProtKB:Q9UM19] xref: EMBL:AB001105 xref: EMBL:AL035404 xref: EMBL:AL136591 xref: EMBL:BC030827 xref: HGNC:HGNC:18212 xref: UniGene:Hs.705422 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062823 ! HPCL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022316 name: HPS1_human def: "Hermansky-Pudlak syndrome 1 protein gene" [UniProtKB:Q92902] synonym: "HPS" EXACT [UniProtKB:Q92902] xref: EMBL:BC000175 xref: EMBL:U65676 xref: EMBL:U79123 xref: EMBL:U79124 xref: EMBL:U79125 xref: EMBL:U79126 xref: EMBL:U79127 xref: EMBL:U79128 xref: EMBL:U79129 xref: EMBL:U79130 xref: EMBL:U79131 xref: EMBL:U79132 xref: EMBL:U79133 xref: EMBL:U79134 xref: EMBL:U79135 xref: EMBL:U79136 xref: EMBL:U96721 xref: HGNC:HGNC:5163 xref: UniGene:Hs.404568 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062978 ! HPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022317 name: HSPH1_human def: "Heat shock protein 105 kDa gene" [UniProtKB:Q92598] synonym: "HSP105" EXACT [UniProtKB:Q92598] synonym: "HSP110" EXACT [UniProtKB:Q92598] synonym: "KIAA0201" EXACT [UniProtKB:Q92598] xref: EMBL:AB003333 xref: EMBL:AB003334 xref: EMBL:AF039695 xref: EMBL:AL137142 xref: EMBL:BC037553 xref: EMBL:CH471075 xref: EMBL:D86956 xref: HGNC:HGNC:16969 xref: UniGene:Hs.36927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063092 ! HS105_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022318 name: HSPA12A_human def: "Heat shock 70 kDa protein 12A gene" [UniProtKB:O43301] synonym: "KIAA0417" EXACT [UniProtKB:O43301] xref: EMBL:AB007877 xref: HGNC:HGNC:19022 xref: UniGene:Hs.654682 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063147 ! HS12A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022319 name: HSPA4L_human def: "Heat shock 70 kDa protein 4L gene" [UniProtKB:O95757] synonym: "APG1" EXACT [UniProtKB:O95757] synonym: "OSP94" EXACT [UniProtKB:O95757] xref: EMBL:AB023421 xref: EMBL:AC093591 xref: EMBL:BC040560 xref: HGNC:HGNC:17041 xref: UniGene:Hs.135554 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063129 ! HS74L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022320 name: HSPB11_human def: "Heat shock protein beta-11 gene" [UniProtKB:Q9Y547] synonym: "C1orf41" EXACT [UniProtKB:Q9Y547] synonym: "HSPC034" EXACT [UniProtKB:Q9Y547] xref: EMBL:AF100747 xref: EMBL:AF416725 xref: EMBL:AF417114 xref: EMBL:AL031427 xref: EMBL:BC005245 xref: EMBL:CH471059 xref: HGNC:HGNC:25019 xref: UniGene:Hs.525462 xref: UniGene:Hs.624686 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062864 ! HSB11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022321 name: HSN2_human def: "Protein HSN2 precursor gene" [UniProtKB:Q6IFS5] xref: EMBL:AC004765 xref: EMBL:BC130467 xref: EMBL:BC130469 xref: EMBL:BK004108 xref: HGNC:HGNC:23152 xref: UniGene:Hs.656067 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063314 ! HSN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022322 name: HSPA4_human def: "Heat shock 70 kDa protein 4 gene" [UniProtKB:P34932] synonym: "APG2" EXACT [UniProtKB:P34932] xref: EMBL:AB023420 xref: EMBL:AC113410 xref: EMBL:BC110861 xref: EMBL:BC126122 xref: EMBL:BC126124 xref: EMBL:L12723 xref: HGNC:HGNC:5237 xref: UniGene:Hs.90093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063096 ! HSP74_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022323 name: HTRA2_human def: "Serine protease HTRA2, mitochondrial precursor gene" [UniProtKB:O43464] synonym: "OMI" EXACT [UniProtKB:O43464] synonym: "PRSS25" EXACT [UniProtKB:O43464] xref: EMBL:AC006544 xref: EMBL:AF020760 xref: EMBL:AF141305 xref: EMBL:AF141306 xref: EMBL:AF141307 xref: EMBL:AF184911 xref: EMBL:BC000096 xref: HGNC:HGNC:14348 xref: UniGene:Hs.469045 xref: UniGene:Hs.591563 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063244 ! HTRA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022324 name: HK1_human def: "Hexokinase-1 gene" [UniProtKB:P19367] xref: EMBL:AC016821 xref: EMBL:AF016349 xref: EMBL:AF016351 xref: EMBL:AF016352 xref: EMBL:AF016353 xref: EMBL:AF016354 xref: EMBL:AF016355 xref: EMBL:AF016356 xref: EMBL:AF016357 xref: EMBL:AF016358 xref: EMBL:AF016359 xref: EMBL:AF016360 xref: EMBL:AF016361 xref: EMBL:AF016362 xref: EMBL:AF016363 xref: EMBL:AF016364 xref: EMBL:AF016365 xref: EMBL:AF029306 xref: EMBL:AF073786 xref: EMBL:AF163910 xref: EMBL:AF163911 xref: EMBL:AF163912 xref: EMBL:AL596223 xref: EMBL:BC008730 xref: EMBL:M75126 xref: EMBL:X66957 xref: HGNC:HGNC:4922 xref: UniGene:Hs.370365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018524 ! HXK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022325 name: IL10RA_human def: "Interleukin-10 receptor alpha chain precursor gene" [UniProtKB:Q13651] synonym: "IL10R" EXACT [UniProtKB:Q13651] xref: EMBL:AY195619 xref: EMBL:BC028082 xref: EMBL:U00672 xref: HGNC:HGNC:5964 xref: UniGene:Hs.504035 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063146 ! I10R1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022326 name: EIF4E1B_human def: "Eukaryotic translation initiation factor 4E type 1B gene" [UniProtKB:A6NMX2] xref: EMBL:AC091934 xref: HGNC:HGNC:33179 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016191 ! I4E1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022327 name: ICAM3_human def: "Intercellular adhesion molecule 3 precursor gene" [UniProtKB:P32942] xref: EMBL:BC058903 xref: EMBL:CH471106 xref: EMBL:DQ217937 xref: EMBL:S50015 xref: EMBL:X69711 xref: EMBL:X69819 xref: HGNC:HGNC:5346 xref: UniGene:Hs.654563 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063239 ! ICAM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022328 name: CLNS1A_human def: "Methylosome subunit pICln gene" [UniProtKB:P54105] synonym: "CLCI" EXACT [UniProtKB:P54105] synonym: "ICLN" EXACT [UniProtKB:P54105] xref: EMBL:AF005422 xref: EMBL:AF026003 xref: EMBL:AF232224 xref: EMBL:AF232225 xref: EMBL:AF232708 xref: EMBL:BC119634 xref: EMBL:BC119635 xref: EMBL:BT019907 xref: EMBL:U17899 xref: EMBL:U53454 xref: EMBL:X91788 xref: HGNC:HGNC:2080 xref: UniGene:Hs.430733 xref: UniGene:Hs.598033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063508 ! ICLN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022329 name: IDH3A_human def: "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor gene" [UniProtKB:P50213] xref: EMBL:AL442090 xref: EMBL:BC021967 xref: EMBL:U07681 xref: HGNC:HGNC:5384 xref: UniGene:Hs.591110 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063070 ! IDH3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022330 name: IDH3B_human def: "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor gene" [UniProtKB:O43837] xref: EMBL:AF023265 xref: EMBL:AF023266 xref: EMBL:AL049712 xref: EMBL:AL050094 xref: EMBL:BC001960 xref: EMBL:U49283 xref: HGNC:HGNC:5385 xref: UniGene:Hs.436405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063220 ! IDH3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022331 name: DNALI1_human def: "Axonemal dynein light intermediate polypeptide 1 gene" [UniProtKB:O14645] xref: EMBL:AF006386 xref: EMBL:AL034379 xref: EMBL:BC039074 xref: EMBL:BC046117 xref: HGNC:HGNC:14353 xref: UniGene:Hs.406050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063174 ! IDLC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022332 name: IDUA_human def: "Alpha-L-iduronidase precursor gene" [UniProtKB:P35475] xref: EMBL:M74715 xref: EMBL:M95739 xref: EMBL:M95740 xref: HGNC:HGNC:5391 xref: UniGene:Hs.89560 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063518 ! IDUA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022333 name: EIF1AY_human def: "Eukaryotic translation initiation factor 1A, Y-chromosomal gene" [UniProtKB:O14602] xref: EMBL:AF000987 xref: EMBL:BC005248 xref: EMBL:BT007201 xref: HGNC:HGNC:3252 xref: UniGene:Hs.461178 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016435 ! IF1AY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022334 name: EIF6_human def: "Eukaryotic translation initiation factor 6 gene" [UniProtKB:P56537] synonym: "EIF3A" EXACT [UniProtKB:P56537] synonym: "ITGB4BP" EXACT [UniProtKB:P56537] synonym: "OK/SW-cl.27" EXACT [UniProtKB:P56537] xref: EMBL:AB062289 xref: EMBL:AF022229 xref: EMBL:AF047433 xref: EMBL:AL121753 xref: EMBL:BC001119 xref: EMBL:BC011845 xref: EMBL:BC019305 xref: EMBL:Y11435 xref: HGNC:HGNC:6159 xref: UniGene:Hs.654848 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063158 ! IF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022335 name: IFRD1_human def: "Interferon-related developmental regulator 1 gene" [UniProtKB:O00458] xref: EMBL:AC005192 xref: EMBL:BC001272 xref: EMBL:BT019889 xref: EMBL:BT019890 xref: EMBL:Y10313 xref: HGNC:HGNC:5456 xref: UniGene:Hs.7879 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063533 ! IFRD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022336 name: IL1RN_human def: "Interleukin-1 receptor antagonist protein precursor gene" [UniProtKB:P18510] synonym: "IL1F3" EXACT [UniProtKB:P18510] synonym: "IL1RA" EXACT [UniProtKB:P18510] xref: EMBL:AF043143 xref: EMBL:AY196903 xref: EMBL:BC009745 xref: EMBL:BN000002 xref: EMBL:M55646 xref: EMBL:M63099 xref: EMBL:U65590 xref: EMBL:X52015 xref: EMBL:X53296 xref: EMBL:X64532 xref: EMBL:X84348 xref: HGNC:HGNC:6000 xref: UniGene:Hs.81134 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063294 ! IL1RA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022337 name: IL33_human def: "Interleukin-33 precursor gene" [UniProtKB:O95760] synonym: "C9orf26" EXACT [UniProtKB:O95760] synonym: "IL1F11" EXACT [UniProtKB:O95760] synonym: "NFHEV" EXACT [UniProtKB:O95760] xref: EMBL:AB024518 xref: EMBL:AL353741 xref: EMBL:AY905581 xref: EMBL:BC047085 xref: EMBL:CR407619 xref: HGNC:HGNC:16028 xref: UniGene:Hs.348390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063254 ! IL33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022338 name: IMP3_human def: "U3 small nucleolar ribonucleoprotein protein IMP3 gene" [UniProtKB:Q9NV31] synonym: "C15orf12" EXACT [UniProtKB:Q9NV31] synonym: "MRPS4" EXACT [UniProtKB:Q9NV31] xref: EMBL:AK001830 xref: EMBL:AK223121 xref: EMBL:AL136913 xref: EMBL:AY050497 xref: EMBL:BC006487 xref: EMBL:BC011745 xref: HGNC:HGNC:14497 xref: UniGene:Hs.513043 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062872 ! IMP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022339 name: INSL6_human def: "Insulin-like peptide INSL6 precursor gene" [UniProtKB:Q9Y581] synonym: "RIF1" EXACT [UniProtKB:Q9Y581] xref: EMBL:AF135824 xref: EMBL:AF156094 xref: EMBL:AL161450 xref: EMBL:BC126473 xref: EMBL:BC126475 xref: HGNC:HGNC:6089 xref: UniGene:Hs.632648 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063224 ! INSL6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022340 name: IPO13_human def: "Importin-13 gene" [UniProtKB:O94829] synonym: "KIAA0724" EXACT [UniProtKB:O94829] synonym: "RANBP13" EXACT [UniProtKB:O94829] xref: EMBL:AB018267 xref: EMBL:AF267987 xref: EMBL:AK023441 xref: EMBL:AL117501 xref: EMBL:AL357079 xref: EMBL:BC008194 xref: EMBL:CH471059 xref: HGNC:HGNC:16853 xref: UniGene:Hs.158497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062870 ! IPO13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022341 name: IPO9_human def: "Importin-9 gene" [UniProtKB:Q96P70] synonym: "HSPC273" EXACT [UniProtKB:Q96P70] synonym: "IMP9" EXACT [UniProtKB:Q96P70] synonym: "KIAA1192" EXACT [UniProtKB:Q96P70] synonym: "RANBP9" EXACT [UniProtKB:Q96P70] xref: EMBL:AB033018 xref: EMBL:AF161391 xref: EMBL:AF410465 xref: EMBL:AK001264 xref: EMBL:AK027532 xref: EMBL:AK074740 xref: EMBL:AK094603 xref: EMBL:AL834323 xref: EMBL:BC003604 xref: HGNC:HGNC:19425 xref: UniGene:Hs.596014 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063077 ! IPO9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022342 name: KCNJ2_human def: "Inward rectifier potassium channel 2 gene" [UniProtKB:P63252] synonym: "HIRK1" EXACT [UniProtKB:P63252] xref: EMBL:AF011904 xref: EMBL:AF021139 xref: EMBL:AF153819 xref: EMBL:AF153820 xref: EMBL:U12507 xref: EMBL:U16861 xref: EMBL:U22413 xref: EMBL:U24055 xref: HGNC:HGNC:6263 xref: UniGene:Hs.1547 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030995 ! IRK2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022343 name: SPINK7_human def: "Serine protease inhibitor Kazal-type 7 precursor gene" [UniProtKB:P58062] synonym: "ECG2" EXACT [UniProtKB:P58062] synonym: "UNQ745/PRO1474" EXACT [UniProtKB:P58062] xref: EMBL:AF268198 xref: EMBL:AY359072 xref: EMBL:BC109385 xref: EMBL:BC110067 xref: HGNC:HGNC:24643 xref: UniGene:Hs.244569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062971 ! ISK7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022344 name: ITM2C_human def: "Integral membrane protein 2C gene" [UniProtKB:Q9NQX7] synonym: "BRI3" EXACT [UniProtKB:Q9NQX7] synonym: "hucep-14" EXACT [UniProtKB:Q9NQX7] synonym: "NPD018" EXACT [UniProtKB:Q9NQX7] synonym: "PSEC0047" EXACT [UniProtKB:Q9NQX7] xref: EMBL:AB003629 xref: EMBL:AF271781 xref: EMBL:AF272043 xref: EMBL:AK075361 xref: EMBL:AK090975 xref: EMBL:AK222697 xref: EMBL:AL136603 xref: EMBL:AL713651 xref: EMBL:AY049777 xref: EMBL:BC002424 xref: EMBL:BC025742 xref: EMBL:BC050668 xref: EMBL:BC098563 xref: EMBL:CR457208 xref: HGNC:HGNC:6175 xref: UniGene:Hs.111577 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062773 ! ITM2C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022345 name: KIAA1199_human def: "Protein KIAA1199 precursor gene" [UniProtKB:Q8WUJ3] xref: EMBL:AB033025 xref: EMBL:AL359061 xref: EMBL:AY007811 xref: EMBL:BC020256 xref: HGNC:HGNC:29213 xref: UniGene:Hs.459088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063148 ! K1199_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022346 name: AK5_human def: "Adenylate kinase isoenzyme 5 gene" [UniProtKB:Q9Y6K8] xref: EMBL:AF062595 xref: EMBL:BC012467 xref: HGNC:HGNC:365 xref: UniGene:Hs.559718 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063488 ! KAD5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022347 name: KBTBD4_human def: "Kelch repeat and BTB domain-containing protein 4 gene" [UniProtKB:Q9NVX7] synonym: "BKLHD4" EXACT [UniProtKB:Q9NVX7] xref: EMBL:AK001312 xref: EMBL:AK001749 xref: EMBL:AL713735 xref: EMBL:BC002736 xref: EMBL:CR457270 xref: HGNC:HGNC:23761 xref: UniGene:Hs.656205 xref: UniGene:Hs.681790 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063519 ! KBTB4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022348 name: KCNAB2_human def: "Voltage-gated potassium channel subunit beta-2 gene" [UniProtKB:Q13303] synonym: "KCNA2B" EXACT [UniProtKB:Q13303] synonym: "KCNK2" EXACT [UniProtKB:Q13303] xref: EMBL:AF029749 xref: EMBL:AF044253 xref: EMBL:AL035406 xref: EMBL:BC126424 xref: EMBL:BC130413 xref: EMBL:U33429 xref: HGNC:HGNC:6229 xref: UniGene:Hs.440497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063325 ! KCAB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022349 name: KCTD15_human def: "BTB/POZ domain-containing protein KCTD15 gene" [UniProtKB:Q96SI1] xref: EMBL:AK027901 xref: EMBL:BC001185 xref: EMBL:BC009335 xref: HGNC:HGNC:23297 xref: UniGene:Hs.221873 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063417 ! KCD15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022350 name: KCNMB1_human def: "Calcium-activated potassium channel subunit beta-1 gene" [UniProtKB:Q16558] xref: EMBL:AF026002 xref: EMBL:AK313979 xref: EMBL:AY044441 xref: EMBL:AY515264 xref: EMBL:BC025707 xref: EMBL:CH471062 xref: EMBL:U25138 xref: EMBL:U38907 xref: EMBL:U42600 xref: EMBL:U42601 xref: EMBL:U42602 xref: EMBL:U42603 xref: EMBL:U61536 xref: EMBL:U61537 xref: HGNC:HGNC:6285 xref: UniGene:Hs.484099 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062962 ! KCMB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022351 name: KEL_human def: "Kell blood group glycoprotein gene" [UniProtKB:P23276] xref: EMBL:AF172609 xref: EMBL:AF172610 xref: EMBL:AF172611 xref: EMBL:AF172612 xref: EMBL:AF172613 xref: EMBL:AF172614 xref: EMBL:AF172615 xref: EMBL:AF172616 xref: EMBL:AF172617 xref: EMBL:AF172618 xref: EMBL:AF172619 xref: EMBL:AF172620 xref: EMBL:AF172621 xref: EMBL:AF172622 xref: EMBL:AF172623 xref: EMBL:AF172624 xref: EMBL:AF172625 xref: EMBL:AF172626 xref: EMBL:AF172627 xref: EMBL:AF279657 xref: EMBL:AY228336 xref: EMBL:BC003135 xref: EMBL:BC050639 xref: EMBL:M64934 xref: EMBL:S80081 xref: HGNC:HGNC:6308 xref: UniGene:Hs.368588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062852 ! KELL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022352 name: MVK_human def: "Mevalonate kinase gene" [UniProtKB:Q03426] xref: EMBL:AF217528 xref: EMBL:AF217529 xref: EMBL:AF217530 xref: EMBL:AF217531 xref: EMBL:AF217532 xref: EMBL:AF217533 xref: EMBL:AF217534 xref: EMBL:AF217535 xref: EMBL:BC016140 xref: EMBL:M88468 xref: EMBL:X75311 xref: HGNC:HGNC:7530 xref: UniGene:Hs.130607 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062953 ! KIME_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022353 name: KIN_human def: "DNA/RNA-binding protein KIN17 gene" [UniProtKB:O60870] synonym: "BTCD" EXACT [UniProtKB:O60870] synonym: "KIN17" EXACT [UniProtKB:O60870] xref: EMBL:AJ005273 xref: EMBL:AL158044 xref: EMBL:BC017309 xref: HGNC:HGNC:6327 xref: UniGene:Hs.397918 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054583 ! KIN17_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022354 name: KLHDC2_human def: "Kelch domain-containing protein 2 gene" [UniProtKB:Q9Y2U9] synonym: "HCA33" EXACT [UniProtKB:Q9Y2U9] xref: EMBL:AF113131 xref: EMBL:AF244137 xref: EMBL:AK001771 xref: EMBL:BC002335 xref: EMBL:BC024192 xref: EMBL:BX161429 xref: EMBL:CH471078 xref: EMBL:CR457205 xref: HGNC:HGNC:20231 xref: UniGene:Hs.509264 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063434 ! KLDC2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022355 name: KLHL8_human def: "Kelch-like protein 8 gene" [UniProtKB:Q9P2G9] synonym: "KIAA1378" EXACT [UniProtKB:Q9P2G9] xref: EMBL:AB037799 xref: EMBL:BC041384 xref: HGNC:HGNC:18644 xref: UniGene:Hs.106601 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063331 ! KLHL8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022356 name: PKM2_human def: "Pyruvate kinase isozymes M1/M2 gene" [UniProtKB:P14618] synonym: "PK2" EXACT [UniProtKB:P14618] synonym: "PK3" EXACT [UniProtKB:P14618] synonym: "PKM" EXACT [UniProtKB:P14618] xref: EMBL:AC020779 xref: EMBL:AF025439 xref: EMBL:AK222927 xref: EMBL:AY352517 xref: EMBL:BC000481 xref: EMBL:BC007640 xref: EMBL:BC007952 xref: EMBL:BC012811 xref: EMBL:BC035198 xref: EMBL:CH471082 xref: EMBL:M23725 xref: EMBL:M26252 xref: EMBL:X56494 xref: HGNC:HGNC:9021 xref: UniGene:Hs.534770 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063029 ! KPYM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022357 name: KRR1_human def: "KRR1 small subunit processome component homolog gene" [UniProtKB:Q13601] synonym: "HRB2" EXACT [UniProtKB:Q13601] xref: EMBL:BC016778 xref: EMBL:BC026107 xref: EMBL:BC033887 xref: EMBL:U55766 xref: HGNC:HGNC:5176 xref: UniGene:Hs.645517 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062817 ! KRR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022358 name: KTN1_human def: "Kinectin gene" [UniProtKB:Q86UP2] synonym: "CG1" EXACT [UniProtKB:Q86UP2] synonym: "KIAA0004" EXACT [UniProtKB:Q86UP2] xref: EMBL:AL138499 xref: EMBL:AY264265 xref: EMBL:BC050555 xref: EMBL:D13629 xref: EMBL:L25616 xref: EMBL:Z22551 xref: HGNC:HGNC:6467 xref: UniGene:Hs.509414 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063140 ! KTN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022359 name: LAIR1_human def: "Leukocyte-associated immunoglobulin-like receptor 1 precursor gene" [UniProtKB:Q6GTX8] synonym: "CD305" EXACT [UniProtKB:Q6GTX8] xref: EMBL:AF013249 xref: EMBL:AF109683 xref: EMBL:AF251509 xref: EMBL:AF251510 xref: EMBL:BC027899 xref: EMBL:CR542051 xref: HGNC:HGNC:6477 xref: UniGene:Hs.572535 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062981 ! LAIR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022360 name: SCRIB_human def: "Protein LAP4 gene" [UniProtKB:Q14160] synonym: "CRIB1" EXACT [UniProtKB:Q14160] synonym: "KIAA0147" EXACT [UniProtKB:Q14160] synonym: "LAP4" EXACT [UniProtKB:Q14160] synonym: "SCRB1" EXACT [UniProtKB:Q14160] synonym: "VARTUL" EXACT [UniProtKB:Q14160] xref: EMBL:AF240677 xref: EMBL:AF271734 xref: EMBL:AY062238 xref: EMBL:BC009490 xref: EMBL:BC014632 xref: EMBL:BC063590 xref: EMBL:D63481 xref: HGNC:HGNC:30377 xref: UniGene:Hs.436329 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063111 ! LAP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022361 name: LASP1_human def: "LIM and SH3 domain protein 1 gene" [UniProtKB:Q14847] synonym: "MLN50" EXACT [UniProtKB:Q14847] xref: EMBL:BC007560 xref: EMBL:BC012460 xref: EMBL:X82456 xref: HGNC:HGNC:6513 xref: UniGene:Hs.548018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062943 ! LASP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022362 name: LDHA_human def: "L-lactate dehydrogenase A chain gene" [UniProtKB:P00338] synonym: "PIG19" EXACT [UniProtKB:P00338] xref: EMBL:AK130587 xref: EMBL:AK223078 xref: EMBL:AY423727 xref: EMBL:BC067223 xref: EMBL:CR456775 xref: EMBL:CR541714 xref: EMBL:S66853 xref: EMBL:X02152 xref: EMBL:X03077 xref: EMBL:X03078 xref: EMBL:X03079 xref: EMBL:X03080 xref: EMBL:X03081 xref: EMBL:X03082 xref: EMBL:X03083 xref: HGNC:HGNC:6535 xref: UniGene:Hs.2795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063179 ! LDHA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022363 name: LDHB_human def: "L-lactate dehydrogenase B chain gene" [UniProtKB:P07195] xref: EMBL:BC002362 xref: EMBL:BC015122 xref: EMBL:BC071860 xref: EMBL:X13794 xref: EMBL:X13795 xref: EMBL:X13796 xref: EMBL:X13797 xref: EMBL:X13798 xref: EMBL:X13799 xref: EMBL:X13800 xref: EMBL:Y00711 xref: HGNC:HGNC:6541 xref: UniGene:Hs.446149 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063130 ! LDHB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022364 name: LDLR_human def: "Low-density lipoprotein receptor precursor gene" [UniProtKB:P01130] xref: EMBL:AY114155 xref: EMBL:AY324609 xref: EMBL:BC014514 xref: EMBL:BT007361 xref: EMBL:L00336 xref: EMBL:L00337 xref: EMBL:L00338 xref: EMBL:L00339 xref: EMBL:L00340 xref: EMBL:L00341 xref: EMBL:L00343 xref: EMBL:L00344 xref: EMBL:L00345 xref: EMBL:L00346 xref: EMBL:L00347 xref: EMBL:L00348 xref: EMBL:L00349 xref: EMBL:L00350 xref: EMBL:L00351 xref: EMBL:L00352 xref: EMBL:L29401 xref: HGNC:HGNC:6547 xref: UniGene:Hs.213289 xref: UniGene:Hs.702603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063373 ! LDLR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022365 name: LGALS3_human def: "Galectin-3 gene" [UniProtKB:P17931] synonym: "MAC2" EXACT [UniProtKB:P17931] xref: EMBL:AB006780 xref: EMBL:AF031422 xref: EMBL:AF031423 xref: EMBL:AF031424 xref: EMBL:AF031425 xref: EMBL:AL139316 xref: EMBL:BC001120 xref: EMBL:BC053667 xref: EMBL:M35368 xref: EMBL:M36682 xref: EMBL:M57710 xref: EMBL:M64303 xref: EMBL:S59012 xref: HGNC:HGNC:6563 xref: UniGene:Hs.531081 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063286 ! LEG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022366 name: LGALS4_human def: "Galectin-4 gene" [UniProtKB:P56470] xref: EMBL:AB006781 xref: EMBL:AF014838 xref: EMBL:BC003661 xref: EMBL:BC005146 xref: EMBL:BC034750 xref: EMBL:U82953 xref: HGNC:HGNC:6565 xref: UniGene:Hs.5302 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062984 ! LEG4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022367 name: LGALS7_human def: "Galectin-7 gene" [UniProtKB:P47929] synonym: "PIG1" EXACT [UniProtKB:P47929] xref: EMBL:BC042911 xref: EMBL:BC061588 xref: EMBL:BC073743 xref: EMBL:L07769 xref: EMBL:U06643 xref: HGNC:HGNC:6568 xref: UniGene:Hs.558355 xref: UniGene:Hs.597642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063118 ! LEG7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022368 name: LEPROTL1_human def: "Leptin receptor overlapping transcript-like 1 gene" [UniProtKB:O95214] synonym: "My047" EXACT [UniProtKB:O95214] synonym: "UNQ577/PRO1139" EXACT [UniProtKB:O95214] xref: EMBL:AF063605 xref: EMBL:AY358674 xref: EMBL:BC000642 xref: HGNC:HGNC:6555 xref: UniGene:Hs.146585 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062940 ! LERL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022369 name: LEUTX_human def: "Putative leucine-twenty homeobox gene" [UniProtKB:A8MZ59] xref: EMBL:AC005393 xref: EMBL:CR746510 xref: HGNC:HGNC:31953 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054137 ! LEUTX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022370 name: LIN7B_human def: "Lin-7 homolog B gene" [UniProtKB:Q9HAP6] synonym: "MALS2" EXACT [UniProtKB:Q9HAP6] synonym: "UNQ3116/PRO10200" EXACT [UniProtKB:Q9HAP6] synonym: "VELI2" EXACT [UniProtKB:Q9HAP6] xref: EMBL:AF311862 xref: EMBL:AY358744 xref: EMBL:BC027618 xref: HGNC:HGNC:17788 xref: UniGene:Hs.221737 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063269 ! LIN7B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022371 name: LIN7C_human def: "Lin-7 homolog C gene" [UniProtKB:Q9NUP9] synonym: "MALS3" EXACT [UniProtKB:Q9NUP9] synonym: "VELI3" EXACT [UniProtKB:Q9NUP9] xref: EMBL:AK002077 xref: EMBL:BC053907 xref: HGNC:HGNC:17789 xref: UniGene:Hs.693840 xref: UniGene:Hs.91393 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063293 ! LIN7C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022372 name: LPL_human def: "Lipoprotein lipase precursor gene" [UniProtKB:P06858] synonym: "LIPD" EXACT [UniProtKB:P06858] xref: EMBL:BC011353 xref: EMBL:BT006726 xref: EMBL:M15856 xref: EMBL:M76722 xref: EMBL:S76076 xref: EMBL:S76077 xref: EMBL:X14390 xref: EMBL:X54516 xref: EMBL:X68111 xref: HGNC:HGNC:6677 xref: UniGene:Hs.180878 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063443 ! LIPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022373 name: LMNA_human def: "Lamin-A/C gene" [UniProtKB:P02545] synonym: "LMN1" EXACT [UniProtKB:P02545] xref: EMBL:AF381029 xref: EMBL:BC000511 xref: EMBL:BC003162 xref: EMBL:BC014507 xref: EMBL:M13451 xref: EMBL:M13452 xref: EMBL:X03444 xref: EMBL:X03445 xref: HGNC:HGNC:6636 xref: UniGene:Hs.594444 xref: UniGene:Hs.647741 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062989 ! LMNA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022374 name: LMNB1_human def: "Lamin-B1 gene" [UniProtKB:P20700] synonym: "LMN2" EXACT [UniProtKB:P20700] synonym: "LMNB" EXACT [UniProtKB:P20700] xref: EMBL:BC012295 xref: EMBL:BC103723 xref: EMBL:L37737 xref: EMBL:L37738 xref: EMBL:L37739 xref: EMBL:L37740 xref: EMBL:L37741 xref: EMBL:L37742 xref: EMBL:L37743 xref: EMBL:L37744 xref: EMBL:L37745 xref: EMBL:L37746 xref: EMBL:L37747 xref: EMBL:M34458 xref: HGNC:HGNC:6637 xref: UniGene:Hs.89497 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063225 ! LMNB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022375 name: LMO7_human def: "LIM domain only protein 7 gene" [UniProtKB:Q8WWI1] synonym: "FBX20" EXACT [UniProtKB:Q8WWI1] synonym: "FBXO20" EXACT [UniProtKB:Q8WWI1] synonym: "KIAA0858" EXACT [UniProtKB:Q8WWI1] xref: EMBL:AB020665 xref: EMBL:AF092554 xref: EMBL:AF092555 xref: EMBL:AF092556 xref: EMBL:AF092557 xref: EMBL:AF144237 xref: EMBL:AF174600 xref: EMBL:AF330045 xref: EMBL:U90654 xref: HGNC:HGNC:6646 xref: UniGene:Hs.207631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063347 ! LMO7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022376 name: LPAR5_human def: "Lysophosphatidic acid receptor 5 gene" [UniProtKB:Q9H1C0] synonym: "GPR92" EXACT [UniProtKB:Q9H1C0] synonym: "GPR93" EXACT [UniProtKB:Q9H1C0] xref: EMBL:AB083600 xref: EMBL:AF411112 xref: EMBL:AJ272207 xref: EMBL:BC033571 xref: EMBL:BC072394 xref: HGNC:HGNC:13307 xref: UniGene:Hs.155538 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058663 ! LPAR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022377 name: LRRN4_human def: "Leucine-rich repeat neuronal protein 4 precursor gene" [UniProtKB:Q8WUT4] synonym: "C20orf75" EXACT [UniProtKB:Q8WUT4] xref: EMBL:AL035461 xref: EMBL:AL118505 xref: EMBL:BC027720 xref: HGNC:HGNC:16208 xref: UniGene:Hs.149133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062827 ! LRRN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022378 name: LSM2_human def: "U6 snRNA-associated Sm-like protein LSm2 gene" [UniProtKB:Q9Y333] synonym: "C6orf28" EXACT [UniProtKB:Q9Y333] synonym: "G7b" EXACT [UniProtKB:Q9Y333] xref: EMBL:AF134726 xref: EMBL:AF136977 xref: EMBL:AF182288 xref: EMBL:AF196468 xref: EMBL:AJ245416 xref: EMBL:BA000025 xref: EMBL:BC009192 xref: HGNC:HGNC:13940 xref: UniGene:Hs.103106 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062972 ! LSM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022379 name: LSM4_human def: "U6 snRNA-associated Sm-like protein LSm4 gene" [UniProtKB:Q9Y4Z0] xref: EMBL:AF117235 xref: EMBL:AF182290 xref: EMBL:AF251218 xref: EMBL:AJ238096 xref: EMBL:BC000387 xref: EMBL:BC003652 xref: EMBL:BC022198 xref: EMBL:BC023665 xref: HGNC:HGNC:17259 xref: UniGene:Hs.515255 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063157 ! LSM4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022380 name: LY6H_human def: "Lymphocyte antigen 6H precursor gene" [UniProtKB:O94772] xref: EMBL:AB012293 xref: EMBL:BC028894 xref: EMBL:BC030192 xref: EMBL:CR457034 xref: HGNC:HGNC:6728 xref: UniGene:Hs.159590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063507 ! LY6H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022381 name: LYAR_human def: "Cell growth-regulating nucleolar protein gene" [UniProtKB:Q9NX58] synonym: "PNAS-5" EXACT [UniProtKB:Q9NX58] xref: EMBL:AF229835 xref: EMBL:AK000432 xref: EMBL:AL136750 xref: EMBL:BC015796 xref: EMBL:CR533548 xref: HGNC:HGNC:26021 xref: UniGene:Hs.425427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063383 ! LYAR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022382 name: LYZ_human def: "Lysozyme C precursor gene" [UniProtKB:P61626] synonym: "LZM" EXACT [UniProtKB:P61626] xref: EMBL:BC004147 xref: EMBL:J03801 xref: EMBL:M19045 xref: EMBL:M21119 xref: EMBL:U25677 xref: EMBL:X14008 xref: HGNC:HGNC:6740 xref: UniGene:Hs.524579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063047 ! LYSC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022383 name: METT11D1_human def: "Protein RSM22 homolog, mitochondrial precursor gene" [UniProtKB:Q9H7H0] xref: EMBL:AF321002 xref: EMBL:AF321003 xref: EMBL:AK024512 xref: EMBL:BC005053 xref: EMBL:CH471078 xref: HGNC:HGNC:19280 xref: UniGene:Hs.512693 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063217 ! M11D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022384 name: M6PRBP1_human def: "Mannose-6-phosphate receptor-binding protein 1 gene" [UniProtKB:O60664] synonym: "TIP47" EXACT [UniProtKB:O60664] xref: EMBL:AF051314 xref: EMBL:AF051315 xref: EMBL:AF055574 xref: EMBL:AF057140 xref: EMBL:AK223054 xref: EMBL:BC001590 xref: EMBL:BC005818 xref: EMBL:BC007566 xref: EMBL:BC019278 xref: EMBL:BT007235 xref: HGNC:HGNC:16893 xref: UniGene:Hs.140452 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063516 ! M6PBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022385 name: MAN2A2_human def: "Alpha-mannosidase 2x gene" [UniProtKB:P49641] synonym: "MANA2X" EXACT [UniProtKB:P49641] xref: EMBL:D55649 xref: EMBL:L28821 xref: HGNC:HGNC:6825 xref: UniGene:Hs.116459 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063384 ! MA2A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022386 name: MAGEC1_human def: "Melanoma-associated antigen C1 gene" [UniProtKB:O60732] xref: EMBL:AF056334 xref: EMBL:AF064589 xref: EMBL:AL022152 xref: HGNC:HGNC:6812 xref: UniGene:Hs.132194 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022509 ! MAGC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022387 name: MAGI2_human def: "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 gene" [UniProtKB:Q86UL8] synonym: "ACVRINP1" EXACT [UniProtKB:Q86UL8] synonym: "AIP1" EXACT [UniProtKB:Q86UL8] synonym: "KIAA0705" EXACT [UniProtKB:Q86UL8] xref: EMBL:AB014605 xref: EMBL:AC004808 xref: EMBL:AC004945 xref: EMBL:AC004990 xref: EMBL:AC005246 xref: EMBL:AC006043 xref: EMBL:AC006324 xref: EMBL:AC007237 xref: EMBL:AC073200 xref: EMBL:AF038563 xref: HGNC:HGNC:18957 xref: UniGene:Hs.654788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063032 ! MAGI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022388 name: MALL_human def: "MAL-like protein gene" [UniProtKB:Q13021] synonym: "BENE" EXACT [UniProtKB:Q13021] xref: EMBL:BC003179 xref: EMBL:U17077 xref: HGNC:HGNC:6818 xref: UniGene:Hs.185055 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062929 ! MALL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022389 name: MATN2_human def: "Matrilin-2 precursor gene" [UniProtKB:O00339] synonym: "UNQ193/PRO219" EXACT [UniProtKB:O00339] xref: EMBL:AL137638 xref: EMBL:AL833931 xref: EMBL:AY358895 xref: EMBL:BC010444 xref: EMBL:BC016394 xref: EMBL:U69263 xref: HGNC:HGNC:6908 xref: UniGene:Hs.189445 xref: UniGene:Hs.660622 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030003 ! MATN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022390 name: MBD4_human def: "Methyl-CpG-binding domain protein 4 gene" [UniProtKB:O95243] synonym: "MED1" EXACT [UniProtKB:O95243] xref: EMBL:AF072250 xref: EMBL:AF114784 xref: EMBL:AF120997 xref: EMBL:AF120998 xref: EMBL:AF120999 xref: EMBL:AF494057 xref: EMBL:AF532602 xref: EMBL:BC011752 xref: EMBL:CR450305 xref: HGNC:HGNC:6919 xref: UniGene:Hs.35947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063002 ! MBD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022391 name: MCOLN1_human def: "Mucolipin-1 gene" [UniProtKB:Q9GZU1] synonym: "ML4" EXACT [UniProtKB:Q9GZU1] synonym: "MSTP080" EXACT [UniProtKB:Q9GZU1] xref: EMBL:AF171088 xref: EMBL:AF249319 xref: EMBL:AF287269 xref: EMBL:AF287270 xref: EMBL:AF305572 xref: EMBL:AF305573 xref: EMBL:AF305574 xref: EMBL:AF305575 xref: EMBL:AF305576 xref: EMBL:AF305577 xref: EMBL:AF305578 xref: EMBL:AF305579 xref: EMBL:AJ293659 xref: EMBL:AJ293970 xref: EMBL:AK026102 xref: EMBL:BC005149 xref: HGNC:HGNC:13356 xref: UniGene:Hs.631858 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028808 ! MCLN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022392 name: MDH1_human def: "Malate dehydrogenase, cytoplasmic gene" [UniProtKB:P40925] synonym: "MDHA" EXACT [UniProtKB:P40925] xref: EMBL:AC016734 xref: EMBL:BC001484 xref: EMBL:CR457405 xref: EMBL:D55654 xref: EMBL:U20352 xref: HGNC:HGNC:6970 xref: UniGene:Hs.526521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063181 ! MDHC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022393 name: ABCB1_human def: "Multidrug resistance protein 1 gene" [UniProtKB:P08183] synonym: "MDR1" EXACT [UniProtKB:P08183] synonym: "PGY1" EXACT [UniProtKB:P08183] xref: EMBL:AC002457 xref: EMBL:AC005068 xref: EMBL:AF016535 xref: EMBL:AY910577 xref: EMBL:M14758 xref: EMBL:M29424 xref: EMBL:M29425 xref: EMBL:M29426 xref: EMBL:M29427 xref: EMBL:M29428 xref: EMBL:M29429 xref: EMBL:M29430 xref: EMBL:M29431 xref: EMBL:M29432 xref: EMBL:M29433 xref: EMBL:M29434 xref: EMBL:M29435 xref: EMBL:M29436 xref: EMBL:M29437 xref: EMBL:M29438 xref: EMBL:M29439 xref: EMBL:M29440 xref: EMBL:M29441 xref: EMBL:M29442 xref: EMBL:M29443 xref: EMBL:M29444 xref: EMBL:M29445 xref: EMBL:M29446 xref: EMBL:M29447 xref: EMBL:M37724 xref: EMBL:M37725 xref: EMBL:X58723 xref: HGNC:HGNC:40 xref: UniGene:Hs.489033 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062993 ! MDR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022394 name: MEIS3P1_human def: "Putative homeobox protein Meis3-like 1 gene" [UniProtKB:A6NDR6] xref: EMBL:AC015922 xref: HGNC:HGNC:7002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032483 ! ME3L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022395 name: MEIS3P2_human def: "Putative homeobox protein Meis3-like 2 gene" [UniProtKB:A8K0S8] xref: EMBL:AC087499 xref: EMBL:AK289643 xref: HGNC:HGNC:17638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0032504 ! ME3L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022396 name: MEP1B_human def: "Meprin A subunit beta precursor gene" [UniProtKB:Q16820] xref: EMBL:AY695931 xref: EMBL:X81333 xref: HGNC:HGNC:7020 xref: UniGene:Hs.194777 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063227 ! MEP1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022397 name: MFSD3_human def: "Major facilitator superfamily domain-containing protein 3 gene" [UniProtKB:Q96ES6] xref: EMBL:BC011982 xref: HGNC:HGNC:25157 xref: UniGene:Hs.7678 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062855 ! MFSD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022398 name: MGA_human def: "MAX gene-associated protein gene" [UniProtKB:Q8IWI9] synonym: "KIAA0518" EXACT [UniProtKB:Q8IWI9] xref: EMBL:AB011090 xref: EMBL:AC016134 xref: EMBL:AC073657 xref: EMBL:AK022696 xref: EMBL:AK023360 xref: EMBL:AL050181 xref: EMBL:BC038449 xref: HGNC:HGNC:14010 xref: UniGene:Hs.187569 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057360 ! MGAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022399 name: MAGOHB_human def: "Protein mago nashi homolog 2 gene" [UniProtKB:Q96A72] synonym: "MAGOH2" EXACT [UniProtKB:Q96A72] xref: EMBL:AF165518 xref: EMBL:AK001154 xref: EMBL:AK022720 xref: EMBL:BC010905 xref: HGNC:HGNC:25504 xref: UniGene:Hs.104650 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062857 ! MGN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022400 name: MAGOH_human def: "Protein mago nashi homolog gene" [UniProtKB:P61326] xref: EMBL:AF035940 xref: EMBL:AF067173 xref: EMBL:AL606760 xref: EMBL:BC018211 xref: HGNC:HGNC:6815 xref: UniGene:Hs.421576 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063234 ! MGN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022401 name: MMP2_human def: "72 kDa type IV collagenase precursor gene" [UniProtKB:P08253] synonym: "CLG4A" EXACT [UniProtKB:P08253] xref: EMBL:AY738117 xref: EMBL:BC002576 xref: EMBL:J03210 xref: EMBL:M33789 xref: EMBL:M55582 xref: EMBL:M55583 xref: EMBL:M55584 xref: EMBL:M55585 xref: EMBL:M55586 xref: EMBL:M55587 xref: EMBL:M55588 xref: EMBL:M55589 xref: EMBL:M55590 xref: EMBL:M55591 xref: EMBL:M55592 xref: EMBL:M55593 xref: EMBL:M58552 xref: HGNC:HGNC:7166 xref: UniGene:Hs.513617 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024617 ! MMP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022402 name: MMTAG2_human def: "Multiple myeloma tumor-associated protein 2 gene" [UniProtKB:Q9BU76] synonym: "C1orf35" EXACT [UniProtKB:Q9BU76] xref: EMBL:AK123377 xref: EMBL:AK126087 xref: EMBL:AL136379 xref: EMBL:AY137773 xref: EMBL:BC002843 xref: EMBL:BC062585 xref: HGNC:HGNC:19032 xref: UniGene:Hs.445952 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062789 ! MMTA2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022403 name: MOCS3_human def: "Molybdenum cofactor synthesis protein 3 gene" [UniProtKB:O95396] xref: EMBL:AF102544 xref: EMBL:AL034553 xref: EMBL:BC015939 xref: HGNC:HGNC:15765 xref: UniGene:Hs.159410 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063161 ! MOCS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022404 name: MRFAP1_human def: "MORF4 family-associated protein 1 gene" [UniProtKB:Q9Y605] synonym: "PAM14" EXACT [UniProtKB:Q9Y605] synonym: "PGR1" EXACT [UniProtKB:Q9Y605] xref: EMBL:AF116272 xref: EMBL:BC022797 xref: EMBL:CR457144 xref: HGNC:HGNC:24549 xref: UniGene:Hs.701277 xref: UniGene:Hs.705528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063194 ! MOFA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022405 name: MORN2_human def: "MORN repeat-containing protein 2 gene" [UniProtKB:Q502X0] synonym: "MOPT" EXACT [UniProtKB:Q502X0] xref: EMBL:AY367766 xref: EMBL:BC095472 xref: EMBL:BC102032 xref: EMBL:BC102034 xref: EMBL:BC102035 xref: HGNC:HGNC:30166 xref: UniGene:Hs.99841 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063520 ! MORN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022406 name: MPDZ_human def: "Multiple PDZ domain protein gene" [UniProtKB:O75970] synonym: "MUPP1" EXACT [UniProtKB:O75970] xref: EMBL:AF093419 xref: EMBL:AJ001319 xref: EMBL:AK098775 xref: EMBL:AL161449 xref: EMBL:AL162386 xref: EMBL:AL353639 xref: EMBL:CH471071 xref: EMBL:CR936648 xref: HGNC:HGNC:7208 xref: UniGene:Hs.169378 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063268 ! MPDZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022407 name: MRFAP1L1_human def: "MORF4 family-associated protein 1-like 1 gene" [UniProtKB:Q96HT8] synonym: "PP784" EXACT [UniProtKB:Q96HT8] xref: EMBL:AF155654 xref: EMBL:AF258591 xref: EMBL:BC008087 xref: EMBL:BC066897 xref: EMBL:CH471131 xref: HGNC:HGNC:28796 xref: UniGene:Hs.593159 xref: UniGene:Hs.695408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062901 ! MR1L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022408 name: MT1H_human def: "Metallothionein-1H gene" [UniProtKB:P80294] xref: EMBL:BC008408 xref: EMBL:BC059780 xref: EMBL:BT007171 xref: EMBL:S68948 xref: EMBL:X64177 xref: EMBL:X64834 xref: HGNC:HGNC:7400 xref: UniGene:Hs.438462 xref: UniGene:Hs.632513 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063279 ! MT1H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022409 name: MTERFD2_human def: "mTERF domain-containing protein 2 gene" [UniProtKB:Q7Z6M4] synonym: "HSPC096" EXACT [UniProtKB:Q7Z6M4] xref: EMBL:AF161359 xref: EMBL:BC053533 xref: HGNC:HGNC:28785 xref: UniGene:Hs.159556 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063317 ! MTER2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022410 name: MTHFS_human def: "5-formyltetrahydrofolate cyclo-ligase gene" [UniProtKB:P49914] xref: EMBL:BC019921 xref: EMBL:L38928 xref: HGNC:HGNC:7437 xref: UniGene:Hs.459049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062961 ! MTHFS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022411 name: MTMR9_human def: "Myotubularin-related protein 9 gene" [UniProtKB:Q96QG7] synonym: "C8orf9" EXACT [UniProtKB:Q96QG7] synonym: "MTMR8" EXACT [UniProtKB:Q96QG7] xref: EMBL:AJ297823 xref: EMBL:AJ297824 xref: EMBL:AK000444 xref: EMBL:BC022003 xref: EMBL:BC034990 xref: EMBL:BC093788 xref: EMBL:BC101623 xref: HGNC:HGNC:14596 xref: UniGene:Hs.591395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0026696 ! MTMR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022412 name: MUC13_human def: "Mucin-13 precursor gene" [UniProtKB:Q9H3R2] synonym: "DRCC1" EXACT [UniProtKB:Q9H3R2] synonym: "RECC" EXACT [UniProtKB:Q9H3R2] synonym: "UNQ6194/PRO20221" EXACT [UniProtKB:Q9H3R2] xref: EMBL:AB035807 xref: EMBL:AF286113 xref: EMBL:AK000070 xref: EMBL:AY358831 xref: HGNC:HGNC:7511 xref: UniGene:Hs.5940 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063197 ! MUC13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022413 name: MUC7_human def: "Mucin-7 precursor gene" [UniProtKB:Q8TAX7] synonym: "MG2" EXACT [UniProtKB:Q8TAX7] xref: EMBL:BC025688 xref: HGNC:HGNC:7518 xref: UniGene:Hs.631946 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063343 ! MUC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022414 name: MUL1_human def: "Mitochondrial ubiquitin ligase activator of NFKB 1 gene" [UniProtKB:Q969V5] synonym: "C1orf166" EXACT [UniProtKB:Q969V5] synonym: "MAPL" EXACT [UniProtKB:Q969V5] synonym: "MULAN" EXACT [UniProtKB:Q969V5] synonym: "RNF218" EXACT [UniProtKB:Q969V5] xref: EMBL:AB097015 xref: EMBL:AK022937 xref: EMBL:AL391357 xref: EMBL:AL833889 xref: EMBL:BC010101 xref: EMBL:BC014010 xref: HGNC:HGNC:25762 xref: UniGene:Hs.10101 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058142 ! MUL1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022415 name: C12orf10_human def: "UPF0160 protein MYG1 gene" [UniProtKB:Q9HB07] xref: EMBL:AF289485 xref: HGNC:HGNC:17590 xref: UniGene:Hs.655988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063184 ! MYG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022416 name: MYL9_human def: "Myosin regulatory light polypeptide 9 gene" [UniProtKB:P24844] synonym: "MLC2" EXACT [UniProtKB:P24844] synonym: "MRLC1" EXACT [UniProtKB:P24844] synonym: "MYRL2" EXACT [UniProtKB:P24844] xref: EMBL:AL050318 xref: EMBL:D82057 xref: EMBL:J02854 xref: HGNC:HGNC:15754 xref: UniGene:Hs.504687 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063421 ! MYL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022417 name: MYO15A_human def: "Myosin-XV gene" [UniProtKB:Q9UKN7] synonym: "MYO15" EXACT [UniProtKB:Q9UKN7] xref: EMBL:AF051976 xref: EMBL:AF144094 xref: HGNC:HGNC:7594 xref: UniGene:Hs.462390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063410 ! MYO15_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022418 name: MYO1A_human def: "Myosin-Ia gene" [UniProtKB:Q9UBC5] synonym: "MYHL" EXACT [UniProtKB:Q9UBC5] xref: EMBL:AF009961 xref: EMBL:AF105424 xref: EMBL:AF127026 xref: EMBL:BC059387 xref: HGNC:HGNC:7595 xref: UniGene:Hs.5394 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063121 ! MYO1A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022419 name: MYO1B_human def: "Myosin-Ib gene" [UniProtKB:O43795] xref: EMBL:AJ001381 xref: EMBL:AJ001382 xref: EMBL:BC053558 xref: HGNC:HGNC:7596 xref: UniGene:Hs.439620 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063101 ! MYO1B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022420 name: MYO1C_human def: "Myosin-Ic gene" [UniProtKB:O00159] xref: EMBL:AK292910 xref: EMBL:BC044891 xref: EMBL:BC068013 xref: EMBL:X98507 xref: HGNC:HGNC:7597 xref: UniGene:Hs.286226 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063063 ! MYO1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022421 name: MYO1D_human def: "Myosin-Id gene" [UniProtKB:O94832] synonym: "KIAA0727" EXACT [UniProtKB:O94832] xref: EMBL:AB018270 xref: EMBL:BC030602 xref: HGNC:HGNC:7598 xref: UniGene:Hs.658000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063055 ! MYO1D_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022422 name: MYO3B_human def: "Myosin-IIIB gene" [UniProtKB:Q8WXR4] xref: EMBL:AC007277 xref: EMBL:AC012594 xref: EMBL:AC068280 xref: EMBL:AC093402 xref: EMBL:AC114794 xref: EMBL:AF369908 xref: EMBL:AF391554 xref: EMBL:AF391555 xref: EMBL:AF391556 xref: EMBL:AF391557 xref: EMBL:AF391558 xref: EMBL:AK055778 xref: HGNC:HGNC:15576 xref: UniGene:Hs.671900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031823 ! MYO3B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022423 name: MYOT_human def: "Myotilin gene" [UniProtKB:Q9UBF9] synonym: "TTID" EXACT [UniProtKB:Q9UBF9] xref: EMBL:AF133820 xref: EMBL:AF144477 xref: EMBL:BC005376 xref: HGNC:HGNC:12399 xref: UniGene:Hs.84665 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063280 ! MYOTI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022424 name: PPP1R12A_human def: "Protein phosphatase 1 regulatory subunit 12A gene" [UniProtKB:O14974] synonym: "MBS" EXACT [UniProtKB:O14974] synonym: "MYPT1" EXACT [UniProtKB:O14974] xref: EMBL:AB042196 xref: EMBL:AF458589 xref: EMBL:AY380574 xref: EMBL:BC047898 xref: EMBL:BC092481 xref: EMBL:BC111752 xref: EMBL:D87930 xref: HGNC:HGNC:7618 xref: UniGene:Hs.49582 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063113 ! MYPT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022425 name: NAGK_human def: "N-acetyl-D-glucosamine kinase gene" [UniProtKB:Q9UJ70] xref: EMBL:AC007881 xref: EMBL:AJ242910 xref: EMBL:AK001812 xref: EMBL:AK222645 xref: EMBL:BC001029 xref: EMBL:BC005371 xref: EMBL:CR457271 xref: HGNC:HGNC:17174 xref: UniGene:Hs.7036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062854 ! NAGK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022426 name: NAIF1_human def: "Nuclear apoptosis-inducing factor 1 gene" [UniProtKB:Q69YI7] synonym: "C9orf90" EXACT [UniProtKB:Q69YI7] xref: EMBL:AL360268 xref: EMBL:AL833392 xref: EMBL:BC021580 xref: HGNC:HGNC:25446 xref: UniGene:Hs.373606 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056712 ! NAIF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022427 name: NBEA_human def: "Neurobeachin gene" [UniProtKB:Q8NFP9] synonym: "BCL8B" EXACT [UniProtKB:Q8NFP9] synonym: "KIAA1544" EXACT [UniProtKB:Q8NFP9] synonym: "LYST2" EXACT [UniProtKB:Q8NFP9] xref: EMBL:AB046764 xref: EMBL:AF072371 xref: EMBL:AF467288 xref: EMBL:AK001059 xref: EMBL:AL137748 xref: EMBL:AL138690 xref: EMBL:AL139083 xref: EMBL:AL159160 xref: EMBL:AL161718 xref: EMBL:AL161902 xref: EMBL:AL356430 xref: EMBL:AL357083 xref: EMBL:AL390071 xref: HGNC:HGNC:7648 xref: UniGene:Hs.491172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063490 ! NBEA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022428 name: NCALD_human def: "Neurocalcin-delta gene" [UniProtKB:P61601] xref: EMBL:AF251061 xref: EMBL:AL136612 xref: EMBL:BC036098 xref: EMBL:BC063428 xref: HGNC:HGNC:7655 xref: UniGene:Hs.492427 xref: UniGene:Hs.680132 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062915 ! NCALD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022429 name: NCBP2_human def: "Nuclear cap-binding protein subunit 2 gene" [UniProtKB:P52298] synonym: "CBP20" EXACT [UniProtKB:P52298] synonym: "PIG55" EXACT [UniProtKB:P52298] xref: EMBL:AY644767 xref: EMBL:BC001255 xref: EMBL:BT006842 xref: EMBL:D59253 xref: EMBL:X84157 xref: HGNC:HGNC:7659 xref: UniGene:Hs.591671 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063016 ! NCBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022430 name: NCF1_human def: "Neutrophil cytosol factor 1 gene" [UniProtKB:P14598] synonym: "NOXO2" EXACT [UniProtKB:P14598] synonym: "SH3PXD1A" EXACT [UniProtKB:P14598] xref: EMBL:AC004883 xref: EMBL:AC083884 xref: EMBL:AC124781 xref: EMBL:AF184614 xref: EMBL:AF330625 xref: EMBL:AF330626 xref: EMBL:AF330627 xref: EMBL:AK127905 xref: EMBL:AK292094 xref: EMBL:BC002816 xref: EMBL:BC065731 xref: EMBL:DQ314878 xref: EMBL:M25665 xref: EMBL:M55067 xref: EMBL:U25793 xref: EMBL:U57833 xref: EMBL:U57834 xref: EMBL:U57835 xref: HGNC:HGNC:7660 xref: UniGene:Hs.647047 xref: UniGene:Hs.655201 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062973 ! NCF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022431 name: NCF2_human def: "Neutrophil cytosol factor 2 gene" [UniProtKB:P19878] synonym: "NOXA2" EXACT [UniProtKB:P19878] synonym: "P67PHOX" EXACT [UniProtKB:P19878] xref: EMBL:AF527950 xref: EMBL:AL137800 xref: EMBL:BC001606 xref: EMBL:BT007439 xref: EMBL:DQ314879 xref: EMBL:M32011 xref: EMBL:U00776 xref: EMBL:U00777 xref: EMBL:U00778 xref: EMBL:U00779 xref: EMBL:U00780 xref: EMBL:U00781 xref: EMBL:U00782 xref: EMBL:U00783 xref: EMBL:U00784 xref: EMBL:U00785 xref: EMBL:U00786 xref: EMBL:U00787 xref: EMBL:U00788 xref: HGNC:HGNC:7661 xref: UniGene:Hs.587558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063026 ! NCF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022432 name: POR_human def: "NADPH--cytochrome P450 reductase gene" [UniProtKB:P16435] synonym: "CYPOR" EXACT [UniProtKB:P16435] xref: EMBL:AB051763 xref: EMBL:AF258341 xref: EMBL:BC034277 xref: EMBL:S90469 xref: HGNC:HGNC:9208 xref: UniGene:Hs.354056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063530 ! NCPR_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022433 name: FREQ_human def: "Neuronal calcium sensor 1 gene" [UniProtKB:P62166] synonym: "FLUP" EXACT [UniProtKB:P62166] synonym: "NCS1" EXACT [UniProtKB:P62166] xref: EMBL:AF134479 xref: EMBL:AF186409 xref: EMBL:AL360004 xref: EMBL:BC004856 xref: EMBL:X84048 xref: HGNC:HGNC:3953 xref: UniGene:Hs.705395 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062861 ! NCS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022434 name: NDRG1_human def: "Protein NDRG1 gene" [UniProtKB:Q92597] synonym: "CAP43" EXACT [UniProtKB:Q92597] synonym: "DRG1" EXACT [UniProtKB:Q92597] synonym: "RTP" EXACT [UniProtKB:Q92597] xref: EMBL:AF004162 xref: EMBL:AF186190 xref: EMBL:AF192304 xref: EMBL:AF230380 xref: EMBL:BC003175 xref: EMBL:D87953 xref: EMBL:X92845 xref: HGNC:HGNC:7679 xref: UniGene:Hs.372914 xref: UniGene:Hs.618002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063438 ! NDRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022435 name: NDUFA6_human def: "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 gene" [UniProtKB:P56556] synonym: "LYRM6" EXACT [UniProtKB:P56556] synonym: "NADHB14" EXACT [UniProtKB:P56556] xref: EMBL:AF047182 xref: EMBL:AL021878 xref: EMBL:BC002772 xref: EMBL:CR456529 xref: HGNC:HGNC:7690 xref: UniGene:Hs.274416 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063422 ! NDUA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022436 name: NDUFA7_human def: "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 gene" [UniProtKB:O95182] xref: EMBL:AF050637 xref: EMBL:AF054178 xref: EMBL:BC003102 xref: HGNC:HGNC:7691 xref: UniGene:Hs.333427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063477 ! NDUA7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022437 name: NDUFB1_human def: "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 gene" [UniProtKB:O75438] xref: EMBL:AF050638 xref: EMBL:AF054181 xref: EMBL:BC009691 xref: HGNC:HGNC:7695 xref: UniGene:Hs.183435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062811 ! NDUB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022438 name: NDUFB9_human def: "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 gene" [UniProtKB:Q9Y6M9] synonym: "LYRM3" EXACT [UniProtKB:Q9Y6M9] synonym: "UQOR22" EXACT [UniProtKB:Q9Y6M9] xref: EMBL:AF044956 xref: EMBL:AF067168 xref: EMBL:AF261090 xref: EMBL:BC007672 xref: HGNC:HGNC:7704 xref: UniGene:Hs.15977 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063423 ! NDUB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022439 name: NDUFS6_human def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial precursor gene" [UniProtKB:O75380] xref: EMBL:AF044959 xref: EMBL:BC038664 xref: EMBL:BC046155 xref: HGNC:HGNC:7713 xref: UniGene:Hs.408257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021658 ! NDUS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022440 name: NDUFS7_human def: "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial precursor gene" [UniProtKB:O75251] xref: EMBL:AC005329 xref: EMBL:BC001715 xref: EMBL:BC005954 xref: EMBL:BC111517 xref: HGNC:HGNC:7714 xref: UniGene:Hs.211914 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063498 ! NDUS7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022441 name: NDUFV1_human def: "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor gene" [UniProtKB:P49821] synonym: "UQOR1" EXACT [UniProtKB:P49821] xref: EMBL:AF053069 xref: EMBL:AF053070 xref: EMBL:AF092131 xref: EMBL:BC008146 xref: EMBL:BC015645 xref: EMBL:S52526 xref: EMBL:S53175 xref: EMBL:S67973 xref: EMBL:Y17379 xref: EMBL:Y17380 xref: EMBL:Y17381 xref: EMBL:Y17382 xref: EMBL:Y17383 xref: HGNC:HGNC:7716 xref: UniGene:Hs.7744 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062888 ! NDUV1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022442 name: NDUFV2_human def: "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial precursor gene" [UniProtKB:P19404] xref: EMBL:BC001632 xref: EMBL:BC017487 xref: EMBL:M22538 xref: HGNC:HGNC:7717 xref: UniGene:Hs.464572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063424 ! NDUV2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022443 name: NECAP2_human def: "Adaptin ear-binding coat-associated protein 2 gene" [UniProtKB:Q9NVZ3] xref: EMBL:AK001282 xref: EMBL:AK023545 xref: EMBL:AK024468 xref: EMBL:AL137802 xref: EMBL:AL669962 xref: EMBL:BC017014 xref: EMBL:BC018914 xref: HGNC:HGNC:25528 xref: UniGene:Hs.437385 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062791 ! NECP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022444 name: SLC9A3R2_human def: "Na(+)/H(+) exchange regulatory cofactor NHE-RF2 gene" [UniProtKB:Q15599] synonym: "NHERF2" EXACT [UniProtKB:Q15599] xref: EMBL:AB014460 xref: EMBL:AB016243 xref: EMBL:AC005600 xref: EMBL:AF004900 xref: EMBL:AF035771 xref: EMBL:BC014513 xref: EMBL:BC106001 xref: EMBL:U82108 xref: EMBL:Z50150 xref: HGNC:HGNC:11076 xref: UniGene:Hs.440896 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025069 ! NHRF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022445 name: NIN_human def: "Ninein gene" [UniProtKB:Q8N4C6] synonym: "KIAA1565" EXACT [UniProtKB:Q8N4C6] xref: EMBL:AB046785 xref: EMBL:AF186776 xref: EMBL:AF212162 xref: EMBL:AF223937 xref: EMBL:AF223938 xref: EMBL:AF223939 xref: EMBL:AF302773 xref: EMBL:AK027054 xref: EMBL:AL133485 xref: EMBL:AL606834 xref: EMBL:AY027794 xref: EMBL:AY027795 xref: EMBL:AY027796 xref: EMBL:BC034708 xref: EMBL:BC065521 xref: HGNC:HGNC:14906 xref: UniGene:Hs.310429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062970 ! NIN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022446 name: NIT1_human def: "Nitrilase homolog 1 gene" [UniProtKB:Q86X76] xref: EMBL:AF069984 xref: EMBL:AF069987 xref: EMBL:BC046149 xref: EMBL:CR541814 xref: EMBL:CR541846 xref: HGNC:HGNC:7828 xref: UniGene:Hs.146406 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063427 ! NIT1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022447 name: SCP2_human def: "Non-specific lipid-transfer protein gene" [UniProtKB:P22307] xref: EMBL:BC005911 xref: EMBL:M55421 xref: EMBL:M75883 xref: EMBL:M75884 xref: EMBL:S52450 xref: EMBL:U11297 xref: EMBL:U11299 xref: EMBL:U11300 xref: EMBL:U11301 xref: EMBL:U11302 xref: EMBL:U11303 xref: EMBL:U11304 xref: EMBL:U11305 xref: EMBL:U11306 xref: EMBL:U11307 xref: EMBL:U11308 xref: EMBL:U11309 xref: EMBL:U11310 xref: EMBL:U11311 xref: EMBL:U11312 xref: EMBL:U11313 xref: HGNC:HGNC:10606 xref: UniGene:Hs.476365 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062969 ! NLTP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022448 name: ZCCHC17_human def: "Nucleolar protein of 40 kDa gene" [UniProtKB:Q9NP64] synonym: "HSPC243" EXACT [UniProtKB:Q9NP64] synonym: "HSPC251" EXACT [UniProtKB:Q9NP64] synonym: "LDC4" EXACT [UniProtKB:Q9NP64] synonym: "PS1D" EXACT [UniProtKB:Q9NP64] xref: EMBL:AF151077 xref: EMBL:AF151085 xref: EMBL:AF247661 xref: EMBL:AK001929 xref: EMBL:AK022506 xref: EMBL:AK024049 xref: EMBL:AL451070 xref: EMBL:BC000685 xref: EMBL:BC007446 xref: EMBL:BC050609 xref: HGNC:HGNC:30246 xref: UniGene:Hs.524094 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062848 ! NO40_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022449 name: NOL4_human def: "Nucleolar protein 4 gene" [UniProtKB:O94818] synonym: "HRIHFB2255" EXACT [UniProtKB:O94818] synonym: "NOLP" EXACT [UniProtKB:O94818] xref: EMBL:AB015339 xref: EMBL:AB017800 xref: EMBL:BC000313 xref: EMBL:BT006763 xref: HGNC:HGNC:7870 xref: UniGene:Hs.514795 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062875 ! NOL4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022450 name: NOTO_human def: "Homeobox protein notochord gene" [UniProtKB:A8MTQ0] xref: EMBL:AC010913 xref: HGNC:HGNC:31839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054033 ! NOTO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022451 name: NOVA1_human def: "RNA-binding protein Nova-1 gene" [UniProtKB:P51513] xref: EMBL:BC075038 xref: EMBL:BC075039 xref: EMBL:U04840 xref: EMBL:Z70771 xref: HGNC:HGNC:7886 xref: UniGene:Hs.31588 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063525 ! NOVA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022452 name: NPDC1_human def: "Neural proliferation differentiation and control protein 1 precursor gene" [UniProtKB:Q9NQX5] xref: EMBL:AF272357 xref: EMBL:AF283247 xref: EMBL:AF285836 xref: EMBL:AL050221 xref: EMBL:AL807752 xref: EMBL:BC004217 xref: HGNC:HGNC:7899 xref: UniGene:Hs.105547 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062902 ! NPDC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022453 name: NPHS1_human def: "Nephrin precursor gene" [UniProtKB:O60500] synonym: "NPHN" EXACT [UniProtKB:O60500] xref: EMBL:AC002133 xref: EMBL:AF035835 xref: EMBL:AF126957 xref: EMBL:AF190637 xref: HGNC:HGNC:7908 xref: UniGene:Hs.590942 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062983 ! NPHN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022454 name: NIPSNAP3A_human def: "Protein NipSnap homolog 3A gene" [UniProtKB:Q9UFN0] synonym: "HSPC299" EXACT [UniProtKB:Q9UFN0] synonym: "NIPSNAP4" EXACT [UniProtKB:Q9UFN0] xref: EMBL:AF161417 xref: EMBL:AK024015 xref: EMBL:AL117557 xref: EMBL:AL359846 xref: EMBL:BC005935 xref: EMBL:CH471105 xref: HGNC:HGNC:23619 xref: UniGene:Hs.591897 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063426 ! NPS3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022455 name: NPY6R_human def: "Putative neuropeptide Y receptor type 6 gene" [UniProtKB:Q99463] synonym: "NPY1RL" EXACT [UniProtKB:Q99463] synonym: "Y2B" EXACT [UniProtKB:Q99463] xref: EMBL:CH471062 xref: EMBL:D86519 xref: EMBL:U59431 xref: EMBL:U67780 xref: HGNC:HGNC:7959 xref: UniGene:Hs.705777 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058413 ! NPY6R_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022456 name: NQO2_human def: "Ribosyldihydronicotinamide dehydrogenase [quinone] gene" [UniProtKB:P16083] synonym: "NMOR2" EXACT [UniProtKB:P16083] xref: EMBL:AB050248 xref: EMBL:AL133351 xref: EMBL:AY299456 xref: EMBL:AY855291 xref: EMBL:BC006096 xref: EMBL:J02888 xref: HGNC:HGNC:7856 xref: UniGene:Hs.533050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063128 ! NQO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022457 name: NRBP1_human def: "Nuclear receptor-binding protein gene" [UniProtKB:Q9UHY1] synonym: "BCON3" EXACT [UniProtKB:Q9UHY1] synonym: "NRBP" EXACT [UniProtKB:Q9UHY1] xref: EMBL:AC074117 xref: EMBL:AF113249 xref: EMBL:AK001946 xref: EMBL:AK027538 xref: EMBL:AK223136 xref: EMBL:AL136682 xref: EMBL:BC001221 xref: HGNC:HGNC:7993 xref: UniGene:Hs.515876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062919 ! NRBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022458 name: NSFL1C_human def: "NSFL1 cofactor p47 gene" [UniProtKB:Q9UNZ2] synonym: "UBXN2C" EXACT [UniProtKB:Q9UNZ2] xref: EMBL:AF078856 xref: EMBL:AF086909 xref: EMBL:AF112211 xref: EMBL:AK001511 xref: EMBL:AL109658 xref: EMBL:BC002801 xref: HGNC:HGNC:15912 xref: UniGene:Hs.12865 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063526 ! NSF1C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022459 name: NSUN4_human def: "Putative methyltransferase NSUN4 gene" [UniProtKB:Q96CB9] xref: EMBL:AK021577 xref: EMBL:AL122001 xref: EMBL:BC014441 xref: EMBL:BC016907 xref: HGNC:HGNC:31802 xref: UniGene:Hs.163424 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062816 ! NSUN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022460 name: NTNG2_human def: "Netrin-G2 precursor gene" [UniProtKB:Q96CW9] synonym: "KIAA1857" EXACT [UniProtKB:Q96CW9] synonym: "LMNT2" EXACT [UniProtKB:Q96CW9] synonym: "UNQ9381/PRO34206" EXACT [UniProtKB:Q96CW9] xref: EMBL:AB058760 xref: EMBL:AY358165 xref: EMBL:BC013770 xref: HGNC:HGNC:14288 xref: UniGene:Hs.163642 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062941 ! NTNG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022461 name: NUP107_human def: "Nuclear pore complex protein Nup107 gene" [UniProtKB:P57740] xref: EMBL:AJ295745 xref: EMBL:BC043343 xref: HGNC:HGNC:29914 xref: UniGene:Hs.524574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063020 ! NU107_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022462 name: NUP133_human def: "Nuclear pore complex protein Nup133 gene" [UniProtKB:Q8WUM0] xref: EMBL:AK001676 xref: EMBL:AK001754 xref: EMBL:AK022572 xref: EMBL:AL121990 xref: EMBL:AL139252 xref: EMBL:AL160004 xref: EMBL:BC020107 xref: HGNC:HGNC:18016 xref: UniGene:Hs.12457 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063021 ! NU133_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022463 name: NUDT14_human def: "Uridine diphosphate glucose pyrophosphatase gene" [UniProtKB:O95848] synonym: "UGPP" EXACT [UniProtKB:O95848] xref: EMBL:AB087802 xref: EMBL:AF111170 xref: EMBL:AL512355 xref: EMBL:BC041584 xref: HGNC:HGNC:20141 xref: UniGene:Hs.526432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063253 ! NUD14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022464 name: NUDT5_human def: "ADP-sugar pyrophosphatase gene" [UniProtKB:Q9UKK9] synonym: "HSPC115" EXACT [UniProtKB:Q9UKK9] xref: EMBL:AF155832 xref: EMBL:AF161464 xref: EMBL:AF218818 xref: EMBL:BC000025 xref: EMBL:CR457195 xref: HGNC:HGNC:8052 xref: UniGene:Hs.555956 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063479 ! NUDT5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022465 name: NUP54_human def: "Nucleoporin p54 gene" [UniProtKB:Q7Z3B4] xref: EMBL:AF157322 xref: EMBL:AK001517 xref: EMBL:BX538002 xref: HGNC:HGNC:17359 xref: UniGene:Hs.430435 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062780 ! NUP54_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022466 name: NXF1_human def: "Nuclear RNA export factor 1 gene" [UniProtKB:Q9UBU9] synonym: "TAP" EXACT [UniProtKB:Q9UBU9] xref: EMBL:AF112880 xref: EMBL:AF126246 xref: EMBL:AJ132712 xref: EMBL:AK027192 xref: EMBL:BC004904 xref: EMBL:BC028041 xref: EMBL:U80073 xref: HGNC:HGNC:8071 xref: UniGene:Hs.523739 xref: UniGene:Hs.601546 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0018046 ! NXF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022467 name: OR10AC1P_human def: "Putative olfactory receptor 10AC1 gene" [UniProtKB:Q8NH08] synonym: "OR10AC1" EXACT [UniProtKB:Q8NH08] xref: EMBL:AB065605 xref: EMBL:BK004748 xref: HGNC:HGNC:14758 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057804 ! O10AC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022468 name: OR10D3P_human def: "Putative olfactory receptor 10D3 gene" [UniProtKB:Q8NH80] synonym: "OR10D3" EXACT [UniProtKB:Q8NH80] xref: EMBL:AB065509 xref: EMBL:BK004425 xref: EMBL:X64983 xref: HGNC:HGNC:8168 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057851 ! O10D3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022469 name: OR14A2_human def: "Olfactory receptor 14A2 gene" [UniProtKB:Q96R54] synonym: "OR5AX1" EXACT [UniProtKB:Q96R54] synonym: "OR5AX1P" EXACT [UniProtKB:Q96R54] xref: EMBL:AB065620 xref: EMBL:AF399589 xref: EMBL:BK004620 xref: HGNC:HGNC:15024 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058365 ! O14A2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022470 name: OR14L1P_human def: "Putative olfactory receptor 14L1 gene" [UniProtKB:Q8NHC6] synonym: "OR5AV1P" EXACT [UniProtKB:Q8NHC6] xref: EMBL:AB065440 xref: EMBL:AL606804 xref: HGNC:HGNC:15023 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057872 ! O14L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022471 name: OAZ1_human def: "Ornithine decarboxylase antizyme gene" [UniProtKB:P54368] synonym: "OAZ" EXACT [UniProtKB:P54368] xref: EMBL:AC004152 xref: EMBL:AY865622 xref: EMBL:D78361 xref: EMBL:D87914 xref: EMBL:D89870 xref: EMBL:U09202 xref: HGNC:HGNC:8095 xref: UniGene:Hs.446427 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063318 ! OAZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022472 name: BCKDHB_human def: "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor gene" [UniProtKB:P21953] xref: EMBL:BC040139 xref: EMBL:D90391 xref: EMBL:M55575 xref: EMBL:U50708 xref: EMBL:X52446 xref: HGNC:HGNC:987 xref: UniGene:Hs.654441 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063238 ! ODBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022473 name: ODF2L_human def: "Outer dense fiber protein 2-like gene" [UniProtKB:Q9ULJ1] synonym: "KIAA1229" EXACT [UniProtKB:Q9ULJ1] xref: EMBL:AB033055 xref: EMBL:AC119749 xref: EMBL:AL136382 xref: EMBL:BC029420 xref: EMBL:BC047368 xref: EMBL:BC091490 xref: EMBL:CH471097 xref: HGNC:HGNC:29225 xref: UniGene:Hs.149360 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063469 ! ODF2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022474 name: PDHA1_human def: "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor gene" [UniProtKB:P08559] synonym: "PHE1A" EXACT [UniProtKB:P08559] xref: EMBL:AF125053 xref: EMBL:AF125054 xref: EMBL:AF125055 xref: EMBL:AF125056 xref: EMBL:AF125057 xref: EMBL:AF125058 xref: EMBL:AF125059 xref: EMBL:AF125060 xref: EMBL:AF125061 xref: EMBL:AF125062 xref: EMBL:AF125063 xref: EMBL:AF125064 xref: EMBL:AF125065 xref: EMBL:AF125066 xref: EMBL:AF125067 xref: EMBL:AF125068 xref: EMBL:AF125069 xref: EMBL:AF125070 xref: EMBL:AF125071 xref: EMBL:AF125072 xref: EMBL:AF125073 xref: EMBL:AF125074 xref: EMBL:AF125075 xref: EMBL:AF125076 xref: EMBL:AF125078 xref: EMBL:AF125079 xref: EMBL:AF125080 xref: EMBL:AF125081 xref: EMBL:AF125082 xref: EMBL:AF125083 xref: EMBL:AF125084 xref: EMBL:AF125085 xref: EMBL:AF125086 xref: EMBL:AF125087 xref: EMBL:AF125088 xref: EMBL:BC002406 xref: EMBL:D90084 xref: EMBL:J03503 xref: EMBL:J03575 xref: EMBL:L13318 xref: EMBL:L48690 xref: EMBL:M24848 xref: EMBL:M27257 xref: EMBL:M29155 xref: EMBL:M29156 xref: EMBL:M29157 xref: EMBL:M29158 xref: EMBL:M29159 xref: EMBL:M29160 xref: EMBL:M29161 xref: EMBL:M29162 xref: EMBL:M29163 xref: EMBL:M29164 xref: EMBL:X52709 xref: EMBL:X52710 xref: HGNC:HGNC:8806 xref: UniGene:Hs.530331 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025860 ! ODPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022475 name: PDHX_human def: "Pyruvate dehydrogenase protein X component, mitochondrial precursor gene" [UniProtKB:O00330] synonym: "PDX1" EXACT [UniProtKB:O00330] xref: EMBL:AF001437 xref: EMBL:AJ298105 xref: EMBL:BC010389 xref: EMBL:U79296 xref: EMBL:U82328 xref: EMBL:Y13145 xref: HGNC:HGNC:21350 xref: UniGene:Hs.502315 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062956 ! ODPX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022476 name: OFD1_human def: "Oral-facial-digital syndrome 1 protein gene" [UniProtKB:O75665] synonym: "CXorf5" EXACT [UniProtKB:O75665] xref: EMBL:BC096344 xref: EMBL:Y15164 xref: EMBL:Y16355 xref: HGNC:HGNC:2567 xref: UniGene:Hs.6483 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063467 ! OFD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022477 name: OIP5_human def: "Opa-interacting protein 5 gene" [UniProtKB:O43482] xref: EMBL:AF025441 xref: EMBL:BC015050 xref: HGNC:HGNC:20300 xref: UniGene:Hs.661645 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063028 ! OIP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022478 name: OR2A1_human def: "Olfactory receptor 2A1/2A42 gene" [UniProtKB:Q8NGT9] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057757 ! OR2A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022479 name: OR2A42_human def: "Olfactory receptor 2A1/2A42 gene" [UniProtKB:Q8NGT9] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057757 ! OR2A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022480 name: OR2W5_human def: "Putative olfactory receptor 2W5 gene" [UniProtKB:A6NFC9] synonym: "OR2W5P" EXACT [UniProtKB:A6NFC9] xref: EMBL:AL606804 xref: EMBL:BC137204 xref: HGNC:HGNC:15424 xref: UniGene:Hs.591526 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053817 ! OR2W5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022481 name: OR2W6P_human def: "Putative olfactory receptor 2W6 gene" [UniProtKB:Q8NHA6] synonym: "OR2W7P" EXACT [UniProtKB:Q8NHA6] xref: EMBL:AB065475 xref: EMBL:BK004697 xref: EMBL:CH471081 xref: HGNC:HGNC:15072 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057862 ! OR2W6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022482 name: OR9A1P_human def: "Putative olfactory receptor 9A1 gene" [UniProtKB:Q8NGU1] synonym: "OR9A1" EXACT [UniProtKB:Q8NGU1] xref: EMBL:AB065690 xref: EMBL:X64982 xref: HGNC:HGNC:8486 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057759 ! OR9A1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022483 name: ORAI2_human def: "Putative protein ORAI2-2 gene" [UniProtKB:Q9H9Y3] synonym: "C7orf19" EXACT [UniProtKB:Q9H9Y3] synonym: "CBCIP2" EXACT [UniProtKB:Q9H9Y3] synonym: "PP1729" EXACT [UniProtKB:Q9H9Y3] synonym: "TMEM142B" EXACT [UniProtKB:Q9H9Y3] xref: EMBL:AC093668 xref: EMBL:AF258552 xref: EMBL:AK022536 xref: EMBL:CR457287 xref: HGNC:HGNC:21667 xref: UniGene:Hs.363308 xref: UniGene:Hs.680539 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063401 ! ORA2P_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022484 name: OS9_human def: "Protein OS-9 precursor gene" [UniProtKB:Q13438] xref: EMBL:AB002805 xref: EMBL:AB002806 xref: EMBL:AC025165 xref: EMBL:CH471054 xref: EMBL:U41635 xref: EMBL:U81031 xref: UniGene:Hs.527861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063250 ! OS9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022485 name: DDOST_human def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor gene" [UniProtKB:P39656] synonym: "KIAA0115" EXACT [UniProtKB:P39656] synonym: "OK/SW-cl.45" EXACT [UniProtKB:P39656] synonym: "OST48" EXACT [UniProtKB:P39656] xref: EMBL:AB062391 xref: EMBL:BC002594 xref: EMBL:D29643 xref: EMBL:D89060 xref: HGNC:HGNC:2728 xref: UniGene:Hs.523145 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063131 ! OST48_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022486 name: OSTA_human def: "Organic solute transporter subunit alpha gene" [UniProtKB:Q86UW1] xref: EMBL:AK172837 xref: EMBL:AY194243 xref: EMBL:CH471191 xref: UniGene:Hs.651164 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063222 ! OSTA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022487 name: OVGP1_human def: "Oviduct-specific glycoprotein precursor gene" [UniProtKB:Q12889] synonym: "MUC9" EXACT [UniProtKB:Q12889] synonym: "OGP" EXACT [UniProtKB:Q12889] xref: EMBL:AL390195 xref: EMBL:BC126177 xref: EMBL:U09550 xref: EMBL:U58001 xref: EMBL:U58002 xref: EMBL:U58003 xref: EMBL:U58004 xref: EMBL:U58005 xref: EMBL:U58006 xref: EMBL:U58007 xref: EMBL:U58008 xref: EMBL:U58009 xref: EMBL:U58010 xref: HGNC:HGNC:8524 xref: UniGene:Hs.1154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029646 ! OVGP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022488 name: PLA2G10_human def: "Group 10 secretory phospholipase A2 precursor gene" [UniProtKB:O15496] xref: EMBL:BC069539 xref: EMBL:BC106731 xref: EMBL:BC106732 xref: EMBL:CR456885 xref: EMBL:U95301 xref: HGNC:HGNC:9029 xref: UniGene:Hs.567366 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063528 ! PA2GX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022489 name: PACSIN1_human def: "Protein kinase C and casein kinase substrate in neurons protein 1 gene" [UniProtKB:Q9BY11] synonym: "KIAA1379" EXACT [UniProtKB:Q9BY11] xref: EMBL:AB037800 xref: EMBL:AF242529 xref: EMBL:AL834211 xref: EMBL:BC040228 xref: HGNC:HGNC:8570 xref: UniGene:Hs.520087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063480 ! PACN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022490 name: PAPOLA_human def: "Poly(A) polymerase alpha gene" [UniProtKB:P51003] synonym: "PAP" EXACT [UniProtKB:P51003] xref: EMBL:BC000927 xref: EMBL:BC036014 xref: EMBL:BX161482 xref: EMBL:BX248301 xref: EMBL:BX248753 xref: EMBL:X76770 xref: HGNC:HGNC:14981 xref: UniGene:Hs.253726 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063134 ! PAPOA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022491 name: TIPARP_human def: "TCDD-inducible poly [ADP-ribose] polymerase gene" [UniProtKB:Q7Z3E1] synonym: "PARP7" EXACT [UniProtKB:Q7Z3E1] xref: EMBL:AL080156 xref: EMBL:BC050350 xref: EMBL:BX537965 xref: EMBL:CR749647 xref: HGNC:HGNC:23696 xref: UniGene:Hs.12813 xref: UniGene:Hs.547611 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063159 ! PARPT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022492 name: PARVA_human def: "Alpha-parvin gene" [UniProtKB:Q9NVD7] synonym: "MXRA2" EXACT [UniProtKB:Q9NVD7] xref: EMBL:AF237771 xref: EMBL:AF325830 xref: EMBL:AK001655 xref: EMBL:AK022316 xref: EMBL:BC014535 xref: EMBL:BC016713 xref: HGNC:HGNC:14652 xref: UniGene:Hs.607144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062876 ! PARVA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022493 name: PDCD10_human def: "Programmed cell death protein 10 gene" [UniProtKB:Q9BUL8] synonym: "CCM3" EXACT [UniProtKB:Q9BUL8] synonym: "TFAR15" EXACT [UniProtKB:Q9BUL8] xref: EMBL:AF022385 xref: EMBL:BC002506 xref: EMBL:BC016353 xref: EMBL:CR457107 xref: HGNC:HGNC:8761 xref: UniGene:Hs.478150 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062768 ! PDC10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022494 name: PDCD6IP_human def: "Programmed cell death 6-interacting protein gene" [UniProtKB:Q8WUM4] synonym: "AIP1" EXACT [UniProtKB:Q8WUM4] synonym: "ALIX" EXACT [UniProtKB:Q8WUM4] synonym: "KIAA1375" EXACT [UniProtKB:Q8WUM4] xref: EMBL:AB037796 xref: EMBL:AF151793 xref: EMBL:AF349951 xref: EMBL:AK002122 xref: EMBL:BC020066 xref: EMBL:BT007367 xref: HGNC:HGNC:8766 xref: UniGene:Hs.475896 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063149 ! PDC6I_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022495 name: PDCD2_human def: "Programmed cell death protein 2 gene" [UniProtKB:Q16342] synonym: "RP8" EXACT [UniProtKB:Q16342] synonym: "ZMYND7" EXACT [UniProtKB:Q16342] xref: EMBL:AL031259 xref: EMBL:BC008378 xref: EMBL:S78085 xref: HGNC:HGNC:8762 xref: UniGene:Hs.367900 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063136 ! PDCD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022496 name: PDIA6_human def: "Protein disulfide-isomerase A6 precursor gene" [UniProtKB:Q15084] synonym: "TXNDC7" EXACT [UniProtKB:Q15084] xref: EMBL:AK127433 xref: EMBL:BC001312 xref: EMBL:D49489 xref: EMBL:U79278 xref: HGNC:HGNC:30168 xref: UniGene:Hs.212102 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063257 ! PDIA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022497 name: POLDIP2_human def: "Polymerase delta-interacting protein 2 gene" [UniProtKB:Q9Y2S7] synonym: "HSPC017" EXACT [UniProtKB:Q9Y2S7] synonym: "PDIP38" EXACT [UniProtKB:Q9Y2S7] synonym: "POLD4" EXACT [UniProtKB:Q9Y2S7] xref: EMBL:AF077203 xref: EMBL:AF179891 xref: EMBL:BC000655 xref: EMBL:BC009265 xref: HGNC:HGNC:23781 xref: UniGene:Hs.241543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063380 ! PDIP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022498 name: PDRG1_human def: "p53 and DNA damage-regulated protein 1 gene" [UniProtKB:Q9NUG6] synonym: "C20orf126" EXACT [UniProtKB:Q9NUG6] synonym: "PDRG" EXACT [UniProtKB:Q9NUG6] xref: EMBL:AL031658 xref: EMBL:AY286301 xref: EMBL:BC001856 xref: EMBL:BC009334 xref: HGNC:HGNC:16119 xref: UniGene:Hs.435755 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063142 ! PDRG1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022499 name: CBFB_human def: "Core-binding factor subunit beta gene" [UniProtKB:Q13951] xref: EMBL:BC018509 xref: EMBL:BT006862 xref: EMBL:L20298 xref: HGNC:HGNC:1539 xref: UniGene:Hs.460988 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063345 ! PEBB_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022500 name: PEBP1_human def: "Phosphatidylethanolamine-binding protein 1 gene" [UniProtKB:P30086] synonym: "PBP" EXACT [UniProtKB:P30086] synonym: "PEBP" EXACT [UniProtKB:P30086] xref: EMBL:BC008714 xref: EMBL:BC017396 xref: EMBL:BC031102 xref: EMBL:D16111 xref: EMBL:S76773 xref: EMBL:X75252 xref: EMBL:X85033 xref: HGNC:HGNC:8630 xref: UniGene:Hs.433863 xref: UniGene:Hs.700567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027514 ! PEBP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022501 name: PELI1_human def: "Protein pellino homolog 1 gene" [UniProtKB:Q96FA3] synonym: "PRISM" EXACT [UniProtKB:Q96FA3] xref: EMBL:AF300987 xref: EMBL:AF302505 xref: EMBL:AJ278859 xref: EMBL:AK027668 xref: EMBL:BC011419 xref: EMBL:BC050019 xref: EMBL:BC063611 xref: HGNC:HGNC:8827 xref: UniGene:Hs.7886 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063242 ! PELI1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022502 name: PELI2_human def: "Protein pellino homolog 2 gene" [UniProtKB:Q9HAT8] xref: EMBL:AF302502 xref: EMBL:BC009476 xref: HGNC:HGNC:8828 xref: UniGene:Hs.657926 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063261 ! PELI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022503 name: PPL_human def: "Periplakin gene" [UniProtKB:O60437] synonym: "KIAA0568" EXACT [UniProtKB:O60437] xref: EMBL:AB011140 xref: EMBL:AF001691 xref: EMBL:AF013717 xref: EMBL:AF040999 xref: EMBL:AF041000 xref: EMBL:AF041002 xref: EMBL:AF041003 xref: EMBL:AF041004 xref: HGNC:HGNC:9273 xref: UniGene:Hs.192233 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063295 ! PEPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022504 name: PXMP3_human def: "Peroxisome assembly factor 1 gene" [UniProtKB:P28328] synonym: "PAF1" EXACT [UniProtKB:P28328] synonym: "PEX2" EXACT [UniProtKB:P28328] synonym: "PMP3" EXACT [UniProtKB:P28328] synonym: "PMP35" EXACT [UniProtKB:P28328] synonym: "RNF72" EXACT [UniProtKB:P28328] xref: EMBL:AF133826 xref: EMBL:BC000661 xref: EMBL:BC005375 xref: EMBL:BC093043 xref: EMBL:M85038 xref: EMBL:M86852 xref: HGNC:HGNC:9717 xref: UniGene:Hs.437966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063388 ! PEX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022505 name: PFDN2_human def: "Prefoldin subunit 2 gene" [UniProtKB:Q9UHV9] synonym: "HSPC231" EXACT [UniProtKB:Q9UHV9] synonym: "PFD2" EXACT [UniProtKB:Q9UHV9] xref: EMBL:AF117237 xref: EMBL:AF151065 xref: EMBL:AF165883 xref: EMBL:BC012464 xref: EMBL:BC047042 xref: HGNC:HGNC:8867 xref: UniGene:Hs.492516 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029133 ! PFD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022506 name: PFDN4_human def: "Prefoldin subunit 4 gene" [UniProtKB:Q9NQP4] synonym: "PFD4" EXACT [UniProtKB:Q9NQP4] xref: EMBL:AL133335 xref: EMBL:BC010953 xref: EMBL:U41816 xref: HGNC:HGNC:8868 xref: UniGene:Hs.91161 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063103 ! PFD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022507 name: PFDN6_human def: "Prefoldin subunit 6 gene" [UniProtKB:O15212] synonym: "HKE2" EXACT [UniProtKB:O15212] synonym: "PFD6" EXACT [UniProtKB:O15212] xref: EMBL:BC039033 xref: EMBL:BC059783 xref: EMBL:Z97184 xref: HGNC:HGNC:4926 xref: UniGene:Hs.446374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063098 ! PFD6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022508 name: PGAM5_human def: "Phosphoglycerate mutase family member 5 precursor gene" [UniProtKB:Q96HS1] xref: EMBL:AC135586 xref: EMBL:AF357523 xref: EMBL:BC008196 xref: HGNC:HGNC:28763 xref: UniGene:Hs.102558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063419 ! PGAM5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022509 name: RABGGTB_human def: "Geranylgeranyl transferase type-2 subunit beta gene" [UniProtKB:P53611] synonym: "GGTB" EXACT [UniProtKB:P53611] xref: EMBL:BC020790 xref: EMBL:U49245 xref: EMBL:X98001 xref: EMBL:Y08201 xref: HGNC:HGNC:9796 xref: UniGene:Hs.78948 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063297 ! PGTB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022510 name: PHYHIPL_human def: "Phytanoyl-CoA hydroxylase-interacting protein-like gene" [UniProtKB:Q96FC7] synonym: "KIAA1796" EXACT [UniProtKB:Q96FC7] synonym: "UNQ6309/PRO20934" EXACT [UniProtKB:Q96FC7] xref: EMBL:AB058699 xref: EMBL:AK054956 xref: EMBL:AL365474 xref: EMBL:AL834339 xref: EMBL:AY358162 xref: EMBL:BC011268 xref: EMBL:CH471083 xref: EMBL:CR749429 xref: HGNC:HGNC:29378 xref: UniGene:Hs.499704 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062900 ! PHIPL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022511 name: PHLDA1_human def: "Pleckstrin homology-like domain family A member 1 gene" [UniProtKB:Q8WV24] synonym: "PHRIP" EXACT [UniProtKB:Q8WV24] synonym: "TDAG51" EXACT [UniProtKB:Q8WV24] xref: EMBL:AF220656 xref: EMBL:AF239986 xref: EMBL:BC018929 xref: EMBL:BC110820 xref: EMBL:Z50194 xref: HGNC:HGNC:8933 xref: UniGene:Hs.602085 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062957 ! PHLA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022512 name: PHPT1_human def: "14 kDa phosphohistidine phosphatase gene" [UniProtKB:Q9NRX4] synonym: "CGI-202" EXACT [UniProtKB:Q9NRX4] synonym: "HSPC141" EXACT [UniProtKB:Q9NRX4] synonym: "PHP14" EXACT [UniProtKB:Q9NRX4] xref: EMBL:AF164795 xref: EMBL:AF285119 xref: EMBL:AF393504 xref: EMBL:AL136644 xref: EMBL:BC024648 xref: HGNC:HGNC:30033 xref: UniGene:Hs.409834 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062779 ! PHP14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022513 name: PIGC_human def: "Phosphatidylinositol N-acetylglucosaminyltransferase subunit C gene" [UniProtKB:Q92535] synonym: "GPI2" EXACT [UniProtKB:Q92535] xref: EMBL:AB000360 xref: EMBL:BC006539 xref: EMBL:BT006734 xref: EMBL:CR450292 xref: EMBL:D85418 xref: EMBL:Z97195 xref: HGNC:HGNC:8960 xref: UniGene:Hs.188456 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063481 ! PIGC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022514 name: PIH1D1_human def: "PIH1 domain-containing protein 1 gene" [UniProtKB:Q9NWS0] synonym: "NOP17" EXACT [UniProtKB:Q9NWS0] xref: EMBL:AK000650 xref: EMBL:BC001108 xref: HGNC:HGNC:26075 xref: UniGene:Hs.5245 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063108 ! PIHD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022515 name: PCMT1_human def: "Protein-L-isoaspartate(D-aspartate) O-methyltransferase gene" [UniProtKB:P22061] xref: EMBL:AL355312 xref: EMBL:BC007501 xref: EMBL:BC008748 xref: EMBL:D13892 xref: EMBL:D25545 xref: EMBL:D25546 xref: EMBL:D25547 xref: EMBL:M93008 xref: EMBL:M93009 xref: EMBL:S73902 xref: EMBL:S73903 xref: EMBL:S73905 xref: EMBL:U49740 xref: HGNC:HGNC:8728 xref: UniGene:Hs.279257 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062985 ! PIMT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022516 name: PIN4_human def: "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 gene" [UniProtKB:Q9Y237] xref: EMBL:AB009690 xref: EMBL:AF143096 xref: EMBL:AL135749 xref: EMBL:BC005234 xref: EMBL:BX119917 xref: HGNC:HGNC:8992 xref: UniGene:Hs.655623 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063394 ! PIN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022517 name: PLEKHA5_human def: "Pleckstrin homology domain-containing family A member 5 gene" [UniProtKB:Q9HAU0] synonym: "KIAA1686" EXACT [UniProtKB:Q9HAU0] synonym: "PEPP2" EXACT [UniProtKB:Q9HAU0] xref: EMBL:AB051473 xref: EMBL:AF302150 xref: EMBL:AK001529 xref: EMBL:AK023127 xref: EMBL:AL834259 xref: EMBL:BC000969 xref: EMBL:BC013133 xref: EMBL:BC127092 xref: HGNC:HGNC:30036 xref: UniGene:Hs.188614 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063010 ! PKHA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022518 name: PLCB2_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 gene" [UniProtKB:Q00722] xref: EMBL:AC020658 xref: EMBL:AK291657 xref: EMBL:M95678 xref: HGNC:HGNC:9055 xref: UniGene:Hs.355888 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024487 ! PLCB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022519 name: PLCZ1_human def: "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 gene" [UniProtKB:Q86YW0] xref: EMBL:AF532185 xref: EMBL:AK292279 xref: EMBL:AY035866 xref: EMBL:BC125067 xref: HGNC:HGNC:19218 xref: UniGene:Hs.97542 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057314 ! PLCZ1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022520 name: PLOD1_human def: "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor gene" [UniProtKB:Q02809] synonym: "LLH" EXACT [UniProtKB:Q02809] synonym: "PLOD" EXACT [UniProtKB:Q02809] xref: EMBL:AF490514 xref: EMBL:AF490515 xref: EMBL:AF490516 xref: EMBL:AF490517 xref: EMBL:AF490518 xref: EMBL:AF490519 xref: EMBL:AF490520 xref: EMBL:AF490521 xref: EMBL:AF490522 xref: EMBL:AF490523 xref: EMBL:AF490524 xref: EMBL:AF490525 xref: EMBL:AF490526 xref: EMBL:AF490527 xref: EMBL:AL096840 xref: EMBL:BC016657 xref: EMBL:L06419 xref: HGNC:HGNC:9081 xref: UniGene:Hs.75093 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063104 ! PLOD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022521 name: PLOD3_human def: "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 precursor gene" [UniProtKB:O60568] xref: EMBL:AC004876 xref: EMBL:AF046889 xref: EMBL:AF068229 xref: EMBL:AF207069 xref: EMBL:AY220458 xref: EMBL:BC011674 xref: HGNC:HGNC:9083 xref: UniGene:Hs.153357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062790 ! PLOD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022522 name: PPP3CA_human def: "Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform gene" [UniProtKB:Q08209] synonym: "CALNA" EXACT [UniProtKB:Q08209] synonym: "CNA" EXACT [UniProtKB:Q08209] xref: EMBL:AL353950 xref: EMBL:BC025714 xref: EMBL:L14778 xref: HGNC:HGNC:9314 xref: UniGene:Hs.435512 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016306 ! PP2BA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022523 name: ACP5_human def: "Tartrate-resistant acid phosphatase type 5 precursor gene" [UniProtKB:P13686] xref: EMBL:BC025414 xref: EMBL:BC111014 xref: EMBL:CR457078 xref: EMBL:J04430 xref: EMBL:X14618 xref: EMBL:X67123 xref: HGNC:HGNC:124 xref: UniGene:Hs.1211 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063418 ! PPA5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022524 name: ACP6_human def: "Lysophosphatidic acid phosphatase type 6 precursor gene" [UniProtKB:Q9NPH0] synonym: "ACPL1" EXACT [UniProtKB:Q9NPH0] synonym: "LPAP" EXACT [UniProtKB:Q9NPH0] synonym: "UNQ205/PRO231" EXACT [UniProtKB:Q9NPH0] xref: EMBL:AB030039 xref: EMBL:AB031478 xref: EMBL:AB209248 xref: EMBL:AK000657 xref: EMBL:AL359207 xref: EMBL:AY358552 xref: EMBL:BC009965 xref: EMBL:BC034686 xref: EMBL:CR457101 xref: HGNC:HGNC:29609 xref: UniGene:Hs.562154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024704 ! PPA6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022525 name: PLN_human def: "Cardiac phospholamban gene" [UniProtKB:P26678] synonym: "PLB" EXACT [UniProtKB:P26678] xref: EMBL:AF177764 xref: EMBL:BC005269 xref: EMBL:M60411 xref: EMBL:M63603 xref: HGNC:HGNC:9080 xref: UniGene:Hs.170839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063298 ! PPLA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022526 name: PRPF38A_human def: "Pre-mRNA-splicing factor 38A gene" [UniProtKB:Q8NAV1] xref: EMBL:AK027842 xref: EMBL:AK092038 xref: EMBL:AL513218 xref: EMBL:BC000777 xref: EMBL:BC063655 xref: EMBL:BC105004 xref: EMBL:BC105006 xref: HGNC:HGNC:25930 xref: UniGene:Hs.5301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063412 ! PR38A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022527 name: PRPF40A_human def: "Pre-mRNA-processing factor 40 homolog A gene" [UniProtKB:O75400] synonym: "FBP11" EXACT [UniProtKB:O75400] synonym: "FLAF1" EXACT [UniProtKB:O75400] synonym: "FNBP3" EXACT [UniProtKB:O75400] synonym: "HSPC225" EXACT [UniProtKB:O75400] synonym: "HYPA" EXACT [UniProtKB:O75400] xref: EMBL:AC012443 xref: EMBL:AC079344 xref: EMBL:AF049523 xref: EMBL:AF049524 xref: EMBL:AF049528 xref: EMBL:AF151059 xref: EMBL:AF155096 xref: EMBL:AK000592 xref: EMBL:AK024810 xref: EMBL:BC011788 xref: EMBL:BC027178 xref: EMBL:U70667 xref: HGNC:HGNC:16463 xref: UniGene:Hs.643580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062999 ! PR40A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022528 name: RABAC1_human def: "Prenylated Rab acceptor protein 1 gene" [UniProtKB:Q9UI14] synonym: "PRA1" EXACT [UniProtKB:Q9UI14] synonym: "PRAF1" EXACT [UniProtKB:Q9UI14] xref: EMBL:AF112202 xref: EMBL:AF112996 xref: EMBL:AJ133534 xref: EMBL:BC008950 xref: EMBL:BT019964 xref: EMBL:CR457214 xref: EMBL:CR542116 xref: HGNC:HGNC:9794 xref: UniGene:Hs.11417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062819 ! PRAF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022529 name: PRG2_human def: "Bone marrow proteoglycan precursor gene" [UniProtKB:P13727] synonym: "MBP" EXACT [UniProtKB:P13727] xref: EMBL:BC005929 xref: EMBL:CR450311 xref: EMBL:M34462 xref: EMBL:M35670 xref: EMBL:M36805 xref: EMBL:X14088 xref: EMBL:X65787 xref: EMBL:Y00809 xref: EMBL:Z26248 xref: HGNC:HGNC:9362 xref: UniGene:Hs.512633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063428 ! PRG2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022530 name: PRKDC_human def: "DNA-dependent protein kinase catalytic subunit gene" [UniProtKB:P78527] synonym: "HYRC" EXACT [UniProtKB:P78527] synonym: "HYRC1" EXACT [UniProtKB:P78527] xref: EMBL:AB052953 xref: EMBL:AB208860 xref: EMBL:AY030284 xref: EMBL:AY316117 xref: EMBL:L27425 xref: EMBL:U34994 xref: EMBL:U35835 xref: EMBL:U47077 xref: EMBL:U63630 xref: EMBL:U90415 xref: HGNC:HGNC:9413 xref: UniGene:Hs.700597 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063076 ! PRKDC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022531 name: PROX2_human def: "Prospero homeobox protein 2 gene" [UniProtKB:Q3B8N5] xref: EMBL:AC006530 xref: EMBL:AK094068 xref: EMBL:BC105720 xref: EMBL:BC105927 xref: HGNC:HGNC:26715 xref: UniGene:Hs.675293 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056246 ! PROX2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022532 name: PRPF3_human def: "U4/U6 small nuclear ribonucleoprotein Prp3 gene" [UniProtKB:O43395] synonym: "HPRP3" EXACT [UniProtKB:O43395] synonym: "PRP3" EXACT [UniProtKB:O43395] xref: EMBL:AF001947 xref: EMBL:AF016370 xref: EMBL:AL611942 xref: EMBL:BC000184 xref: EMBL:BC001954 xref: EMBL:CH471121 xref: HGNC:HGNC:17348 xref: UniGene:Hs.11776 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062912 ! PRPF3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022533 name: PRPS1_human def: "Ribose-phosphate pyrophosphokinase 1 gene" [UniProtKB:P60891] xref: EMBL:AL137787 xref: EMBL:AL772400 xref: EMBL:BC001605 xref: EMBL:CH471120 xref: EMBL:D00860 xref: EMBL:X15331 xref: HGNC:HGNC:9462 xref: UniGene:Hs.56 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030301 ! PRPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022534 name: PRR13_human def: "Proline-rich protein 13 gene" [UniProtKB:Q9NZ81] synonym: "BM-041" EXACT [UniProtKB:Q9NZ81] xref: EMBL:AF217517 xref: EMBL:BC014257 xref: EMBL:BC016064 xref: EMBL:BC066943 xref: EMBL:BX640962 xref: EMBL:CR533459 xref: HGNC:HGNC:24528 xref: UniGene:Hs.426359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062926 ! PRR13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022535 name: PRR14_human def: "Proline-rich protein 14 gene" [UniProtKB:Q9BWN1] xref: EMBL:AK074783 xref: EMBL:BC000119 xref: EMBL:BC021934 xref: EMBL:BC050677 xref: EMBL:CH471192 xref: HGNC:HGNC:28458 xref: UniGene:Hs.293629 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062882 ! PRR14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022536 name: PRRT2_human def: "Proline-rich transmembrane protein 2 gene" [UniProtKB:Q7Z6L0] xref: EMBL:AK074572 xref: EMBL:AK092265 xref: EMBL:AL834185 xref: EMBL:BC011405 xref: EMBL:BC053594 xref: HGNC:HGNC:30500 xref: UniGene:Hs.655071 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063486 ! PRRT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022537 name: PTCD3_human def: "Pentatricopeptide repeat-containing protein 3, mitochondrial precursor gene" [UniProtKB:Q96EY7] synonym: "TRG15" EXACT [UniProtKB:Q96EY7] xref: EMBL:AK000765 xref: EMBL:AL832520 xref: EMBL:AY277598 xref: EMBL:BC001758 xref: EMBL:BC011832 xref: HGNC:HGNC:24717 xref: UniGene:Hs.323489 xref: UniGene:Hs.623885 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063510 ! PTCD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022538 name: PTGDS_human def: "Prostaglandin-H2 D-isomerase precursor gene" [UniProtKB:P41222] synonym: "PDS" EXACT [UniProtKB:P41222] xref: EMBL:AL807752 xref: EMBL:AY026356 xref: EMBL:BC005939 xref: EMBL:BC041463 xref: EMBL:BT019921 xref: EMBL:BT019922 xref: EMBL:DQ297141 xref: EMBL:M61900 xref: EMBL:M98537 xref: EMBL:M98538 xref: HGNC:HGNC:9592 xref: UniGene:Hs.446429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063329 ! PTGDS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022539 name: PTCHD2_human def: "Patched domain-containing protein 2 gene" [UniProtKB:Q9P2K9] synonym: "DISP3" EXACT [UniProtKB:Q9P2K9] synonym: "KIAA1337" EXACT [UniProtKB:Q9P2K9] xref: EMBL:AB037758 xref: EMBL:AL031735 xref: EMBL:AL117235 xref: EMBL:AL117236 xref: EMBL:AL590989 xref: HGNC:HGNC:29251 xref: UniGene:Hs.202355 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063476 ! PTHD2_HUMAN relationship: codes_for CCO:B0063502 ! Q9UJD7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022540 name: PTPN13_human def: "Tyrosine-protein phosphatase non-receptor type 13 gene" [UniProtKB:Q12923] synonym: "PNP1" EXACT [UniProtKB:Q12923] synonym: "PTP1E" EXACT [UniProtKB:Q12923] synonym: "PTPL1" EXACT [UniProtKB:Q12923] xref: EMBL:AF233323 xref: EMBL:BC039610 xref: EMBL:D21209 xref: EMBL:D21210 xref: EMBL:D21211 xref: EMBL:L34583 xref: EMBL:U12128 xref: EMBL:X79676 xref: EMBL:X80289 xref: HGNC:HGNC:9646 xref: UniGene:Hs.436142 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063042 ! PTN13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022541 name: PTPN2_human def: "Tyrosine-protein phosphatase non-receptor type 2 gene" [UniProtKB:P17706] synonym: "PTPT" EXACT [UniProtKB:P17706] xref: EMBL:BC008244 xref: EMBL:M25393 xref: EMBL:M81478 xref: HGNC:HGNC:9650 xref: UniGene:Hs.654527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063302 ! PTN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022542 name: PTPN4_human def: "Tyrosine-protein phosphatase non-receptor type 4 gene" [UniProtKB:P29074] xref: EMBL:BC010674 xref: EMBL:M68941 xref: HGNC:HGNC:9656 xref: UniGene:Hs.469809 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063349 ! PTN4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022543 name: PTPRK_human def: "Receptor-type tyrosine-protein phosphatase kappa precursor gene" [UniProtKB:Q15262] synonym: "PTPK" EXACT [UniProtKB:Q15262] xref: EMBL:AL034349 xref: EMBL:AL035465 xref: EMBL:AL035470 xref: EMBL:AL035594 xref: EMBL:AL357621 xref: EMBL:AL451073 xref: EMBL:AL590006 xref: EMBL:L77886 xref: EMBL:Z70660 xref: HGNC:HGNC:9674 xref: UniGene:Hs.155919 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0022999 ! PTPRK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022544 name: PAICS_human def: "Multifunctional protein ADE2 gene" [UniProtKB:P22234] synonym: "ADE2" EXACT [UniProtKB:P22234] synonym: "AIRC" EXACT [UniProtKB:P22234] synonym: "PAIS" EXACT [UniProtKB:P22234] xref: EMBL:BC010273 xref: EMBL:BC019255 xref: EMBL:BT006988 xref: EMBL:X53793 xref: HGNC:HGNC:8587 xref: UniGene:Hs.518774 xref: UniGene:Hs.705514 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063387 ! PUR6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022545 name: PVRL2_human def: "Poliovirus receptor-related protein 2 precursor gene" [UniProtKB:Q92692] synonym: "HVEB" EXACT [UniProtKB:Q92692] synonym: "PRR2" EXACT [UniProtKB:Q92692] xref: EMBL:AF044962 xref: EMBL:AF044963 xref: EMBL:AF044964 xref: EMBL:AF044966 xref: EMBL:AF044967 xref: EMBL:AF044968 xref: EMBL:AF050154 xref: EMBL:AF058448 xref: EMBL:BC003091 xref: EMBL:X80038 xref: HGNC:HGNC:9707 xref: UniGene:Hs.655455 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062928 ! PVRL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022546 name: PYGM_human def: "Glycogen phosphorylase, muscle form gene" [UniProtKB:P11217] xref: EMBL:AF066859 xref: EMBL:BC126392 xref: EMBL:BC130514 xref: EMBL:M16013 xref: EMBL:M32579 xref: EMBL:M32580 xref: EMBL:M32581 xref: EMBL:M32582 xref: EMBL:M32583 xref: EMBL:M32584 xref: EMBL:M32585 xref: EMBL:M32586 xref: EMBL:M32587 xref: EMBL:M32588 xref: EMBL:M32589 xref: EMBL:M32590 xref: EMBL:M32591 xref: EMBL:M32592 xref: EMBL:M32593 xref: EMBL:M32594 xref: EMBL:M32595 xref: EMBL:M32596 xref: EMBL:M32597 xref: EMBL:M32598 xref: EMBL:U94774 xref: EMBL:U94775 xref: EMBL:U94776 xref: EMBL:U94777 xref: EMBL:X03031 xref: HGNC:HGNC:9726 xref: UniGene:Hs.154084 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063116 ! PYGM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022547 name: CAD_human def: "CAD protein gene" [UniProtKB:P27708] xref: EMBL:BC065510 xref: EMBL:D78586 xref: EMBL:M38561 xref: HGNC:HGNC:1424 xref: UniGene:Hs.377010 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063066 ! PYR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022548 name: UMPS_human def: "Uridine 5'-monophosphate synthase gene" [UniProtKB:P11172] synonym: "OK/SW-cl.21" EXACT [UniProtKB:P11172] xref: EMBL:AB041359 xref: EMBL:AB062285 xref: EMBL:AL080099 xref: EMBL:AY691629 xref: EMBL:BC000364 xref: EMBL:BC007511 xref: EMBL:CR456787 xref: EMBL:D86227 xref: EMBL:D86228 xref: EMBL:D86230 xref: EMBL:J03626 xref: EMBL:M36661 xref: HGNC:HGNC:12563 xref: UniGene:Hs.2057 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063493 ! PYR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022549 name: UQCRQ_human def: "Cytochrome b-c1 complex subunit 8 gene" [UniProtKB:O14949] xref: EMBL:BC001390 xref: EMBL:BC090048 xref: EMBL:D50369 xref: HGNC:HGNC:29594 xref: UniGene:Hs.146602 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063503 ! QCR8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022550 name: QSK_human def: "Serine/threonine-protein kinase QSK gene" [UniProtKB:Q9Y2K2] synonym: "KIAA0999" EXACT [UniProtKB:Q9Y2K2] synonym: "L19" EXACT [UniProtKB:Q9Y2K2] synonym: "SIK3" EXACT [UniProtKB:Q9Y2K2] xref: EMBL:AB023216 xref: EMBL:AB209327 xref: EMBL:AK022302 xref: EMBL:AY598338 xref: EMBL:BC035583 xref: EMBL:BC063887 xref: EMBL:BC086858 xref: UniGene:Hs.167451 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063019 ! QSK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022551 name: RAB3IL1_human def: "Guanine nucleotide exchange factor for Rab3A gene" [UniProtKB:Q8TBN0] xref: EMBL:AF084557 xref: EMBL:BC022239 xref: EMBL:BC051820 xref: HGNC:HGNC:9780 xref: UniGene:Hs.13759 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062830 ! R3GEF_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022552 name: R3HDM2_human def: "R3H domain-containing protein 2 gene" [UniProtKB:Q9Y2K5] synonym: "KIAA1002" EXACT [UniProtKB:Q9Y2K5] xref: EMBL:AB023219 xref: EMBL:AC126614 xref: EMBL:AC137834 xref: EMBL:BC041857 xref: EMBL:BC104995 xref: EMBL:BC112226 xref: HGNC:HGNC:29167 xref: UniGene:Hs.443673 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063316 ! R3HD2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022553 name: RAB31_human def: "Ras-related protein Rab-31 gene" [UniProtKB:Q13636] synonym: "RAB22B" EXACT [UniProtKB:Q13636] xref: EMBL:AF183421 xref: EMBL:AF234995 xref: EMBL:AF498957 xref: EMBL:BC001148 xref: EMBL:BT020027 xref: EMBL:BT020028 xref: EMBL:CR407659 xref: EMBL:U57091 xref: EMBL:U59877 xref: HGNC:HGNC:9771 xref: UniGene:Hs.99528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063521 ! RAB31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022554 name: RABEP1_human def: "Rab GTPase-binding effector protein 1 gene" [UniProtKB:Q15276] synonym: "RABPT5" EXACT [UniProtKB:Q15276] synonym: "RABPT5A" EXACT [UniProtKB:Q15276] xref: EMBL:AF098638 xref: EMBL:BC041700 xref: EMBL:X91141 xref: HGNC:HGNC:17677 xref: UniGene:Hs.592121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063285 ! RABE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022555 name: RADIL_human def: "Ras-associating and dilute domain-containing protein gene" [UniProtKB:Q96JH8] synonym: "KIAA1849" EXACT [UniProtKB:Q96JH8] xref: EMBL:AB058752 xref: EMBL:AC092610 xref: EMBL:AK000997 xref: EMBL:AK001186 xref: EMBL:AL136731 xref: EMBL:BC004919 xref: EMBL:BC117317 xref: EMBL:BC126311 xref: EMBL:CH471144 xref: EMBL:EF560723 xref: UniGene:Hs.667336 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058240 ! RADIL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022556 name: RAI2_human def: "Retinoic acid-induced protein 2 gene" [UniProtKB:Q9Y5P3] xref: EMBL:AF136587 xref: EMBL:BC027937 xref: EMBL:Z93242 xref: HGNC:HGNC:9835 xref: UniGene:Hs.446680 xref: UniGene:Hs.701485 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062845 ! RAI2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022557 name: RANBP9_human def: "Ran-binding protein 9 gene" [UniProtKB:Q96S59] synonym: "RANBPM" EXACT [UniProtKB:Q96S59] xref: EMBL:AB008515 xref: EMBL:AB055311 xref: EMBL:AF306510 xref: EMBL:AL441883 xref: EMBL:BC019886 xref: EMBL:BC052781 xref: EMBL:BC063849 xref: EMBL:Z93020 xref: HGNC:HGNC:13727 xref: UniGene:Hs.702006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063004 ! RANB9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022558 name: RASSF9_human def: "Ras association domain-containing protein 9 gene" [UniProtKB:O75901] synonym: "PAMCI" EXACT [UniProtKB:O75901] synonym: "PCIP1" EXACT [UniProtKB:O75901] xref: EMBL:AF056209 xref: EMBL:BC031589 xref: HGNC:HGNC:15739 xref: UniGene:Hs.527881 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054676 ! RASF9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022559 name: RBM41_human def: "RNA-binding protein 41 gene" [UniProtKB:Q96IZ5] xref: EMBL:AK001878 xref: EMBL:AK023732 xref: EMBL:AL390039 xref: EMBL:BC006986 xref: HGNC:HGNC:25617 xref: UniGene:Hs.139053 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062777 ! RBM41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022560 name: RBM42_human def: "RNA-binding protein 42 gene" [UniProtKB:Q9BTD8] xref: EMBL:AC002115 xref: EMBL:BC002868 xref: EMBL:BC004204 xref: EMBL:BC031682 xref: HGNC:HGNC:28117 xref: UniGene:Hs.5086 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062859 ! RBM42_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022561 name: RCN1_human def: "Reticulocalbin-1 precursor gene" [UniProtKB:Q15293] synonym: "RCN" EXACT [UniProtKB:Q15293] xref: EMBL:AL078612 xref: EMBL:BC010120 xref: EMBL:D42073 xref: HGNC:HGNC:9934 xref: UniGene:Hs.97887 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063210 ! RCN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022562 name: RCN2_human def: "Reticulocalbin-2 precursor gene" [UniProtKB:Q14257] synonym: "ERC55" EXACT [UniProtKB:Q14257] xref: EMBL:BC004892 xref: EMBL:X78669 xref: HGNC:HGNC:9935 xref: UniGene:Hs.79088 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063088 ! RCN2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022563 name: RAD23A_human def: "UV excision repair protein RAD23 homolog A gene" [UniProtKB:P54725] xref: EMBL:AD000092 xref: EMBL:AF549209 xref: EMBL:BC014026 xref: EMBL:D21235 xref: HGNC:HGNC:9812 xref: UniGene:Hs.643267 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062849 ! RD23A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022564 name: REPS1_human def: "RalBP1-associated Eps domain-containing protein 1 gene" [UniProtKB:Q96D71] xref: EMBL:AF251052 xref: EMBL:AL121834 xref: EMBL:AL831900 xref: EMBL:BC012764 xref: EMBL:BC021211 xref: HGNC:HGNC:15578 xref: UniGene:Hs.334603 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063199 ! REPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022565 name: RER1_human def: "Protein RER1 gene" [UniProtKB:O15258] xref: EMBL:AF091071 xref: EMBL:AJ001421 xref: EMBL:BC004965 xref: HGNC:HGNC:30309 xref: UniGene:Hs.525527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063432 ! RER1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022566 name: RFX7_human def: "DNA-binding protein RFX7 gene" [UniProtKB:Q2KHR2] synonym: "RFXDC2" EXACT [UniProtKB:Q2KHR2] xref: EMBL:AK023056 xref: EMBL:AK024757 xref: EMBL:AK126103 xref: EMBL:AK128045 xref: EMBL:AL834302 xref: EMBL:BC112936 xref: HGNC:HGNC:25777 xref: UniGene:Hs.282855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056202 ! RFX7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022567 name: RICS_human def: "Rho/Cdc42/Rac GTPase-activating protein RICS gene" [UniProtKB:A7KAX9] synonym: "GRIT" EXACT [UniProtKB:A7KAX9] synonym: "KIAA0712" EXACT [UniProtKB:A7KAX9] xref: EMBL:AB018255 xref: EMBL:AB079856 xref: EMBL:AY194287 xref: EMBL:BC000277 xref: EMBL:BC051236 xref: EMBL:BC065371 xref: EMBL:BC104898 xref: EMBL:BC113429 xref: EMBL:CH471065 xref: EMBL:EF127492 xref: UniGene:Hs.440379 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053947 ! RICS_HUMAN relationship: codes_for CCO:B0063319 ! Q86UT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022568 name: RFK_human def: "Riboflavin kinase gene" [UniProtKB:Q969G6] xref: EMBL:AK002011 xref: EMBL:AL391868 xref: EMBL:BC007069 xref: HGNC:HGNC:30324 xref: UniGene:Hs.37558 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063430 ! RIFK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022569 name: RPL10_human def: "60S ribosomal protein L10 gene" [UniProtKB:P27635] synonym: "DXS648E" EXACT [UniProtKB:P27635] synonym: "QM" EXACT [UniProtKB:P27635] xref: EMBL:AB007170 xref: EMBL:AF486812 xref: EMBL:AK223309 xref: EMBL:BC003358 xref: EMBL:BC026276 xref: EMBL:BC071918 xref: EMBL:BX936346 xref: EMBL:BX936347 xref: EMBL:CR456797 xref: EMBL:CR542069 xref: EMBL:DQ369703 xref: EMBL:DQ369704 xref: EMBL:DQ369705 xref: EMBL:DQ369706 xref: EMBL:DQ369707 xref: EMBL:DQ369708 xref: EMBL:DQ369709 xref: EMBL:DQ369710 xref: EMBL:DQ369711 xref: EMBL:DQ369712 xref: EMBL:DQ369713 xref: EMBL:DQ369714 xref: EMBL:DQ369715 xref: EMBL:DQ369716 xref: EMBL:L44140 xref: EMBL:M64241 xref: EMBL:M73791 xref: EMBL:M81806 xref: EMBL:S35960 xref: EMBL:S64168 xref: EMBL:S64169 xref: HGNC:HGNC:10298 xref: UniGene:Hs.534404 xref: UniGene:Hs.657751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063093 ! RL10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022570 name: RPL14_human def: "60S ribosomal protein L14 gene" [UniProtKB:P50914] xref: EMBL:AB046407 xref: EMBL:AB061822 xref: EMBL:AC104186 xref: EMBL:BC000606 xref: EMBL:BC005134 xref: EMBL:BC009294 xref: EMBL:BC019651 xref: EMBL:BC022805 xref: EMBL:BC029036 xref: EMBL:D87735 xref: EMBL:U16738 xref: HGNC:HGNC:10305 xref: UniGene:Hs.446522 xref: UniGene:Hs.653959 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063090 ! RL14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022571 name: RSL1D1_human def: "Ribosomal L1 domain-containing protein 1 gene" [UniProtKB:O76021] synonym: "CATX11" EXACT [UniProtKB:O76021] synonym: "CSIG" EXACT [UniProtKB:O76021] synonym: "L12" EXACT [UniProtKB:O76021] synonym: "PBK1" EXACT [UniProtKB:O76021] xref: EMBL:AF083127 xref: EMBL:AJ007398 xref: EMBL:AL049999 xref: EMBL:AY154473 xref: EMBL:AY598331 xref: EMBL:BC019069 xref: EMBL:BC112228 xref: EMBL:BC113699 xref: HGNC:HGNC:24534 xref: UniGene:Hs.401842 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063260 ! RL1D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022572 name: RPL23A_human def: "60S ribosomal protein L23a gene" [UniProtKB:P62750] xref: EMBL:AF001689 xref: EMBL:BC014459 xref: EMBL:BC058041 xref: EMBL:L13799 xref: EMBL:U02032 xref: EMBL:U37230 xref: EMBL:U43701 xref: HGNC:HGNC:10317 xref: UniGene:Hs.419463 xref: UniGene:Hs.705476 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063360 ! RL23A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022573 name: RPL26_human def: "60S ribosomal protein L26 gene" [UniProtKB:P61254] xref: EMBL:AB061829 xref: EMBL:BC071664 xref: EMBL:L07287 xref: EMBL:X69392 xref: HGNC:HGNC:10327 xref: UniGene:Hs.482144 xref: UniGene:Hs.694762 xref: UniGene:Hs.696165 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063367 ! RL26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022574 name: RPL27A_human def: "60S ribosomal protein L27a gene" [UniProtKB:P46776] xref: EMBL:AB007178 xref: EMBL:AB020236 xref: EMBL:BC005326 xref: EMBL:BC020169 xref: EMBL:U14968 xref: HGNC:HGNC:10329 xref: UniGene:Hs.523463 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063356 ! RL27A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022575 name: RPL29_human def: "60S ribosomal protein L29 gene" [UniProtKB:P47914] xref: EMBL:BC008926 xref: EMBL:BC070190 xref: EMBL:BC070481 xref: EMBL:BC071663 xref: EMBL:U10248 xref: EMBL:U49083 xref: EMBL:Z49148 xref: HGNC:HGNC:10331 xref: UniGene:Hs.425125 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0028895 ! RL29_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022576 name: RPL31_human def: "60S ribosomal protein L31 gene" [UniProtKB:P62899] xref: EMBL:AB061830 xref: EMBL:AC016738 xref: EMBL:BC017343 xref: EMBL:BC070373 xref: EMBL:X15940 xref: EMBL:X69181 xref: HGNC:HGNC:10334 xref: UniGene:Hs.469473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015391 ! RL31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022577 name: RPL35A_human def: "60S ribosomal protein L35a gene" [UniProtKB:P18077] synonym: "GIG33" EXACT [UniProtKB:P18077] xref: EMBL:AY871273 xref: EMBL:BC001037 xref: EMBL:BC010949 xref: EMBL:BC017093 xref: EMBL:BC061890 xref: EMBL:CH471252 xref: EMBL:X52966 xref: EMBL:X94619 xref: HGNC:HGNC:10345 xref: UniGene:Hs.529631 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063048 ! RL35A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022578 name: RPL35_human def: "60S ribosomal protein L35 gene" [UniProtKB:P42766] xref: EMBL:AB046409 xref: EMBL:AL354928 xref: EMBL:BC000348 xref: EMBL:BC010919 xref: EMBL:BC071915 xref: EMBL:BC094828 xref: EMBL:CR456877 xref: EMBL:U12465 xref: HGNC:HGNC:10344 xref: UniGene:Hs.182825 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063091 ! RL35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022579 name: RPL36_human def: "60S ribosomal protein L36 gene" [UniProtKB:Q9Y3U8] xref: EMBL:AB061833 xref: EMBL:AF077043 xref: EMBL:AL050273 xref: EMBL:BC003052 xref: EMBL:BC004971 xref: EMBL:BC091508 xref: EMBL:CR533465 xref: HGNC:HGNC:13631 xref: UniGene:Hs.408018 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029592 ! RL36_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022580 name: RPL3_human def: "60S ribosomal protein L3 gene" [UniProtKB:P39023] synonym: "OK/SW-cl.32" EXACT [UniProtKB:P39023] xref: EMBL:AB007166 xref: EMBL:AB062291 xref: EMBL:AL022326 xref: EMBL:BC002408 xref: EMBL:BC006483 xref: EMBL:BC008003 xref: EMBL:BC012146 xref: EMBL:BC012786 xref: EMBL:BC013674 xref: EMBL:BC014017 xref: EMBL:BC015032 xref: EMBL:BC015767 xref: EMBL:BC063662 xref: EMBL:BC088373 xref: EMBL:BC107711 xref: EMBL:CR456566 xref: EMBL:L22453 xref: EMBL:M90054 xref: EMBL:X73460 xref: HGNC:HGNC:10332 xref: UniGene:Hs.119598 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063083 ! RL3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022581 name: RPL5_human def: "60S ribosomal protein L5 gene" [UniProtKB:P46777] synonym: "MSTP030" EXACT [UniProtKB:P46777] xref: EMBL:AF113210 xref: EMBL:AK222604 xref: EMBL:AL162740 xref: EMBL:U14966 xref: EMBL:U76609 xref: EMBL:Z35312 xref: HGNC:HGNC:10360 xref: UniGene:Hs.180946 xref: UniGene:Hs.532359 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063183 ! RL5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022582 name: RPL9_human def: "60S ribosomal protein L9 gene" [UniProtKB:P32969] synonym: "OK/SW-cl.103" EXACT [UniProtKB:P32969] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062885 ! RL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022583 name: RPL9P7_human def: "60S ribosomal protein L9 gene" [UniProtKB:P32969] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062885 ! RL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022584 name: RPL9P8_human def: "60S ribosomal protein L9 gene" [UniProtKB:P32969] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062885 ! RL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022585 name: RPL9P9_human def: "60S ribosomal protein L9 gene" [UniProtKB:P32969] is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062885 ! RL9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022586 name: C15orf15_human def: "Probable ribosome biogenesis protein RLP24 gene" [UniProtKB:Q9UHA3] synonym: "My024" EXACT [UniProtKB:Q9UHA3] synonym: "RPL24L" EXACT [UniProtKB:Q9UHA3] xref: EMBL:AF060926 xref: EMBL:AF165521 xref: EMBL:AF201949 xref: EMBL:AF212226 xref: EMBL:BC008409 xref: EMBL:BC008422 xref: EMBL:BC008449 xref: EMBL:BC008499 xref: EMBL:BC009593 xref: EMBL:BC009604 xref: EMBL:BC012913 xref: EMBL:BC014576 xref: EMBL:BC016312 xref: EMBL:BC016331 xref: EMBL:BC016725 xref: EMBL:BC016777 xref: EMBL:BC026266 xref: EMBL:BC026267 xref: EMBL:BC028672 xref: EMBL:BC035995 xref: EMBL:BC093067 xref: EMBL:CR457179 xref: HGNC:HGNC:18479 xref: UniGene:Hs.274772 xref: UniGene:Hs.593056 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062909 ! RLP24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022587 name: MRPL38_human def: "39S ribosomal protein L38, mitochondrial precursor gene" [UniProtKB:Q96DV4] synonym: "HSPC262" EXACT [UniProtKB:Q96DV4] xref: EMBL:AB051345 xref: EMBL:AF161380 xref: EMBL:BC013311 xref: HGNC:HGNC:14033 xref: UniGene:Hs.442609 xref: UniGene:Hs.658049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063523 ! RM38_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022588 name: MRPL44_human def: "39S ribosomal protein L44, mitochondrial precursor gene" [UniProtKB:Q9H9J2] xref: EMBL:AC073641 xref: EMBL:AK022763 xref: EMBL:AK024052 xref: EMBL:BC012058 xref: EMBL:CR457293 xref: HGNC:HGNC:16650 xref: UniGene:Hs.203559 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063385 ! RM44_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022589 name: RNF138_human def: "E3 ubiquitin-protein ligase RNF138 gene" [UniProtKB:Q8WVD3] synonym: "HSD-4" EXACT [UniProtKB:Q8WVD3] synonym: "HSD4" EXACT [UniProtKB:Q8WVD3] synonym: "NARF" EXACT [UniProtKB:Q8WVD3] xref: EMBL:AF162680 xref: EMBL:AK023579 xref: EMBL:AL133557 xref: EMBL:BC018107 xref: EMBL:BT006878 xref: EMBL:CR457150 xref: HGNC:HGNC:17765 xref: UniGene:Hs.302408 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063219 ! RN138_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022590 name: RNF146_human def: "RING finger protein 146 gene" [UniProtKB:Q9NTX7] xref: EMBL:AJ315122 xref: EMBL:AK027558 xref: EMBL:AK027776 xref: EMBL:AL109939 xref: EMBL:AL136829 xref: EMBL:BC008235 xref: EMBL:CR533514 xref: HGNC:HGNC:21336 xref: UniGene:Hs.267120 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063484 ! RN146_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022591 name: RNF183_human def: "RING finger protein 183 gene" [UniProtKB:Q96D59] xref: EMBL:BC013036 xref: HGNC:HGNC:28721 xref: UniGene:Hs.211374 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062846 ! RN183_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022592 name: RNASE6_human def: "Ribonuclease K6 precursor gene" [UniProtKB:Q93091] synonym: "RNS6" EXACT [UniProtKB:Q93091] xref: EMBL:BC020848 xref: EMBL:U64998 xref: HGNC:HGNC:10048 xref: UniGene:Hs.23262 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063440 ! RNAS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022593 name: RNF11_human def: "RING finger protein 11 gene" [UniProtKB:Q9Y3C5] synonym: "CGI-123" EXACT [UniProtKB:Q9Y3C5] xref: EMBL:AB024703 xref: EMBL:AF151881 xref: EMBL:BC020964 xref: EMBL:BC047654 xref: HGNC:HGNC:10056 xref: UniGene:Hs.696036 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062996 ! RNF11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022594 name: RNPS1_human def: "RNA-binding protein with serine-rich domain 1 gene" [UniProtKB:Q15287] synonym: "LDC2" EXACT [UniProtKB:Q15287] xref: EMBL:AF015608 xref: EMBL:AF247662 xref: EMBL:AF274003 xref: EMBL:BC001659 xref: EMBL:BC001838 xref: EMBL:BC108316 xref: EMBL:L37368 xref: HGNC:HGNC:10080 xref: UniGene:Hs.355643 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062889 ! RNPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022595 name: ELAC2_human def: "Zinc phosphodiesterase ELAC protein 2 gene" [UniProtKB:Q9BQ52] synonym: "HPC2" EXACT [UniProtKB:Q9BQ52] xref: EMBL:AF304369 xref: EMBL:AF304370 xref: EMBL:AK001392 xref: EMBL:AK124838 xref: EMBL:AK125030 xref: EMBL:BC001939 xref: EMBL:BC004158 xref: EMBL:CR457261 xref: HGNC:HGNC:14198 xref: UniGene:Hs.434232 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063441 ! RNZ2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022596 name: TRIM21_human def: "52 kDa Ro protein gene" [UniProtKB:P19474] synonym: "RNF81" EXACT [UniProtKB:P19474] synonym: "RO52" EXACT [UniProtKB:P19474] synonym: "SSA1" EXACT [UniProtKB:P19474] xref: EMBL:AF391283 xref: EMBL:BC010861 xref: EMBL:M34551 xref: EMBL:M62800 xref: EMBL:U01882 xref: EMBL:U13657 xref: EMBL:U13658 xref: HGNC:HGNC:11312 xref: UniGene:Hs.532357 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062892 ! RO52_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022597 name: POLR1A_human def: "DNA-directed RNA polymerase I subunit RPA1 gene" [UniProtKB:O95602] xref: EMBL:AL117467 xref: EMBL:BC117173 xref: EMBL:BC126303 xref: EMBL:U33460 xref: EMBL:U33823 xref: EMBL:U33824 xref: HGNC:HGNC:17264 xref: UniGene:Hs.531818 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063137 ! RPA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022598 name: POLR1E_human def: "DNA-directed RNA polymerase I subunit RPA49 gene" [UniProtKB:Q9GZS1] synonym: "PAF53" EXACT [UniProtKB:Q9GZS1] synonym: "PRAF1" EXACT [UniProtKB:Q9GZS1] xref: EMBL:AK023452 xref: EMBL:AK024032 xref: EMBL:AK091294 xref: EMBL:AL158156 xref: EMBL:BC001337 xref: EMBL:BC014331 xref: EMBL:CR457313 xref: HGNC:HGNC:17631 xref: UniGene:Hs.591087 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063135 ! RPA49_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022599 name: POLR2E_human def: "DNA-directed RNA polymerases I, II, and III subunit RPABC1 gene" [UniProtKB:P19388] xref: EMBL:AC004151 xref: EMBL:BC004441 xref: EMBL:BC034144 xref: EMBL:D38251 xref: EMBL:J04965 xref: EMBL:S42643 xref: HGNC:HGNC:9192 xref: UniGene:Hs.24301 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063167 ! RPAB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022600 name: POLR2H_human def: "DNA-directed RNA polymerases I, II, and III subunit RPABC3 gene" [UniProtKB:P52434] xref: EMBL:AJ252079 xref: EMBL:AJ252080 xref: EMBL:BC000739 xref: EMBL:U37689 xref: EMBL:Z49199 xref: HGNC:HGNC:9195 xref: UniGene:Hs.432574 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063138 ! RPAB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022601 name: RPAP3_human def: "RNA polymerase II-associated protein 3 gene" [UniProtKB:Q9H6T3] xref: EMBL:AK025561 xref: EMBL:BC056415 xref: EMBL:CH471111 xref: HGNC:HGNC:26151 xref: UniGene:Hs.437855 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063095 ! RPAP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022602 name: POLR2J_human def: "DNA-directed RNA polymerase II subunit RPB11-a gene" [UniProtKB:P52435] synonym: "POLR2J1" EXACT [UniProtKB:P52435] xref: EMBL:AC093668 xref: EMBL:BC024165 xref: EMBL:BC065711 xref: EMBL:L37127 xref: EMBL:X82385 xref: EMBL:X98433 xref: HGNC:HGNC:9197 xref: UniGene:Hs.654952 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063165 ! RPB11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022603 name: POLR2B_human def: "DNA-directed RNA polymerase II subunit RPB2 gene" [UniProtKB:P30876] xref: EMBL:AF055028 xref: EMBL:BC023503 xref: EMBL:X63563 xref: HGNC:HGNC:9188 xref: UniGene:Hs.602757 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063168 ! RPB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022604 name: POLR2G_human def: "DNA-directed RNA polymerase II subunit RPB7 gene" [UniProtKB:P62487] xref: EMBL:BC112162 xref: EMBL:BC112164 xref: EMBL:U20659 xref: EMBL:U52427 xref: HGNC:HGNC:9194 xref: UniGene:Hs.14839 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063166 ! RPB7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022605 name: RAPGEFL1_human def: "Rap guanine nucleotide exchange factor-like 1 gene" [UniProtKB:Q9UHV5] xref: EMBL:AC068669 xref: EMBL:AF117946 xref: EMBL:AK313492 xref: EMBL:BC029956 xref: EMBL:BC115374 xref: EMBL:BC115375 xref: HGNC:HGNC:17428 xref: UniGene:Hs.632254 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059150 ! RPGFL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022606 name: POLRMT_human def: "DNA-directed RNA polymerase, mitochondrial precursor gene" [UniProtKB:O00411] xref: EMBL:AC004449 xref: EMBL:U75370 xref: HGNC:HGNC:9200 xref: UniGene:Hs.254113 xref: UniGene:Hs.512026 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063040 ! RPOM_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022607 name: RRAGD_human def: "Ras-related GTP-binding protein D gene" [UniProtKB:Q9NQL2] xref: EMBL:AF272036 xref: EMBL:AL137502 xref: EMBL:AL138717 xref: EMBL:BC003088 xref: HGNC:HGNC:19903 xref: UniGene:Hs.485938 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063034 ! RRAGD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022608 name: PDCD11_human def: "Protein RRP5 homolog gene" [UniProtKB:Q14690] synonym: "KIAA0185" EXACT [UniProtKB:Q14690] xref: EMBL:AL139339 xref: EMBL:AL591408 xref: EMBL:AL603983 xref: EMBL:AY007124 xref: EMBL:BC049838 xref: EMBL:CH471066 xref: EMBL:D80007 xref: HGNC:HGNC:13408 xref: UniGene:Hs.239499 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062995 ! RRP5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022609 name: RPS11_human def: "40S ribosomal protein S11 gene" [UniProtKB:P62280] xref: EMBL:AB007152 xref: EMBL:AB028893 xref: EMBL:BC007283 xref: EMBL:BC007603 xref: EMBL:BC007945 xref: EMBL:BC010028 xref: EMBL:BC016378 xref: EMBL:BC070224 xref: EMBL:BC100025 xref: EMBL:X06617 xref: HGNC:HGNC:10384 xref: UniGene:Hs.433529 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063085 ! RS11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022610 name: RPS16_human def: "40S ribosomal protein S16 gene" [UniProtKB:P62249] xref: EMBL:AB061841 xref: EMBL:BC004324 xref: EMBL:BC007977 xref: EMBL:M60854 xref: HGNC:HGNC:10396 xref: UniGene:Hs.397609 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063078 ! RS16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022611 name: RPS23_human def: "40S ribosomal protein S23 gene" [UniProtKB:P62266] xref: EMBL:AB007158 xref: EMBL:BC070221 xref: EMBL:CR456996 xref: EMBL:D14530 xref: HGNC:HGNC:10410 xref: UniGene:Hs.527193 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030465 ! RS23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022612 name: RPS26_human def: "40S ribosomal protein S26 gene" [UniProtKB:P62854] xref: EMBL:BC002604 xref: EMBL:BC015832 xref: EMBL:BC070220 xref: EMBL:BC105276 xref: EMBL:BC105798 xref: EMBL:U41448 xref: EMBL:X69654 xref: EMBL:X77770 xref: EMBL:X79236 xref: HGNC:HGNC:10414 xref: UniGene:Hs.447562 xref: UniGene:Hs.567235 xref: UniGene:Hs.632726 xref: UniGene:Hs.660737 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063353 ! RS26_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022613 name: RPS28_human def: "40S ribosomal protein S28 gene" [UniProtKB:P62857] xref: EMBL:AB007164 xref: EMBL:AB061846 xref: EMBL:BC000354 xref: EMBL:BC021239 xref: EMBL:BC070217 xref: EMBL:BC070218 xref: EMBL:CR457055 xref: EMBL:L05091 xref: EMBL:U58682 xref: HGNC:HGNC:10418 xref: UniGene:Hs.153177 xref: UniGene:Hs.322473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063368 ! RS28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022614 name: RPS2_human def: "40S ribosomal protein S2 gene" [UniProtKB:P15880] synonym: "RPS4" EXACT [UniProtKB:P15880] xref: EMBL:BC001795 xref: EMBL:BC006559 xref: EMBL:BC008862 xref: EMBL:BC010165 xref: EMBL:BC012354 xref: EMBL:BC016178 xref: EMBL:BC016951 xref: EMBL:BC018993 xref: EMBL:BC021545 xref: EMBL:BC023541 xref: EMBL:BC025677 xref: EMBL:BC066321 xref: EMBL:BC068051 xref: EMBL:BC071922 xref: EMBL:BC071923 xref: EMBL:BC071924 xref: EMBL:BC073966 xref: EMBL:BC075830 xref: EMBL:BC103756 xref: EMBL:BC105985 xref: EMBL:X17206 xref: HGNC:HGNC:10404 xref: UniGene:Hs.356366 xref: UniGene:Hs.381079 xref: UniGene:Hs.498569 xref: UniGene:Hs.506997 xref: UniGene:Hs.698340 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063474 ! RS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022615 name: RPS5_human def: "40S ribosomal protein S5 gene" [UniProtKB:P46782] xref: EMBL:AB007149 xref: EMBL:AB061853 xref: EMBL:BC015405 xref: EMBL:BC018151 xref: EMBL:U14970 xref: HGNC:HGNC:10426 xref: UniGene:Hs.378103 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063061 ! RS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022616 name: RPS6_human def: "40S ribosomal protein S6 gene" [UniProtKB:P62753] synonym: "OK/SW-cl.2" EXACT [UniProtKB:P62753] xref: EMBL:AB062123 xref: EMBL:BC000524 xref: EMBL:BC009427 xref: EMBL:BC027620 xref: EMBL:BC071907 xref: EMBL:BC071908 xref: EMBL:BC094826 xref: EMBL:J03537 xref: EMBL:M20020 xref: EMBL:M77232 xref: EMBL:X67309 xref: HGNC:HGNC:10429 xref: UniGene:Hs.408073 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0015901 ! RS6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022617 name: RSRC1_human def: "Arginine/serine-rich coiled-coil protein 1 gene" [UniProtKB:Q96IZ7] synonym: "BM-011" EXACT [UniProtKB:Q96IZ7] xref: EMBL:AF208853 xref: EMBL:BC006982 xref: EMBL:BC010357 xref: HGNC:HGNC:24152 xref: UniGene:Hs.591283 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063376 ! RSRC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022618 name: MRPS18B_human def: "28S ribosomal protein S18b, mitochondrial precursor gene" [UniProtKB:Q9Y676] synonym: "HSPC183" EXACT [UniProtKB:Q9Y676] synonym: "PTD017" EXACT [UniProtKB:Q9Y676] xref: EMBL:AB110933 xref: EMBL:AB110934 xref: EMBL:AB202094 xref: EMBL:AF100761 xref: EMBL:AF151017 xref: EMBL:AL050361 xref: EMBL:AL662800 xref: EMBL:AL662825 xref: EMBL:AL732442 xref: EMBL:AL845353 xref: EMBL:BC005373 xref: EMBL:BX119957 xref: EMBL:BX248507 xref: EMBL:CH471081 xref: EMBL:CR753328 xref: HGNC:HGNC:14516 xref: UniGene:Hs.655329 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062930 ! RT18B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022619 name: MRPS31_human def: "28S ribosomal protein S31, mitochondrial precursor gene" [UniProtKB:Q92665] synonym: "IMOGN38" EXACT [UniProtKB:Q92665] xref: EMBL:AL161614 xref: EMBL:AL355132 xref: EMBL:BC022045 xref: EMBL:Z68747 xref: HGNC:HGNC:16632 xref: UniGene:Hs.154655 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063466 ! RT31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022620 name: SNRPA1_human def: "U2 small nuclear ribonucleoprotein A' gene" [UniProtKB:P09661] xref: EMBL:BC022816 xref: EMBL:BC071717 xref: EMBL:X13482 xref: HGNC:HGNC:11152 xref: UniGene:Hs.528763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063189 ! RU2A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022621 name: RWDD2B_human def: "RWD domain-containing protein 2B gene" [UniProtKB:P57060] synonym: "C21orf6" EXACT [UniProtKB:P57060] synonym: "GL011" EXACT [UniProtKB:P57060] xref: EMBL:AF212232 xref: EMBL:AK000056 xref: EMBL:AL163249 xref: EMBL:BC012546 xref: EMBL:BC017912 xref: EMBL:Y19009 xref: HGNC:HGNC:1302 xref: UniGene:Hs.34136 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062767 ! RWD2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022622 name: RWDD1_human def: "RWD domain-containing protein 1 gene" [UniProtKB:Q9H446] synonym: "CGI-24" EXACT [UniProtKB:Q9H446] synonym: "DFRP2" EXACT [UniProtKB:Q9H446] synonym: "PTD013" EXACT [UniProtKB:Q9H446] xref: EMBL:AF092134 xref: EMBL:AF132958 xref: EMBL:AL121953 xref: EMBL:BC015802 xref: HGNC:HGNC:20993 xref: UniGene:Hs.532164 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062936 ! RWDD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022623 name: S100P_human def: "Protein S100-P gene" [UniProtKB:P25815] synonym: "S100E" EXACT [UniProtKB:P25815] xref: EMBL:AF539739 xref: EMBL:BC006819 xref: EMBL:BT007289 xref: EMBL:X65614 xref: HGNC:HGNC:10504 xref: UniGene:Hs.2962 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062804 ! S100P_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022624 name: SS18L1_human def: "SS18-like protein 1 gene" [UniProtKB:O75177] synonym: "KIAA0693" EXACT [UniProtKB:O75177] xref: EMBL:AB014593 xref: EMBL:AL078633 xref: EMBL:BC034494 xref: HGNC:HGNC:15592 xref: UniGene:Hs.154429 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062865 ! S18L1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022625 name: S1PR2_human def: "Sphingosine 1-phosphate receptor 2 gene" [UniProtKB:O95136] synonym: "EDG5" EXACT [UniProtKB:O95136] xref: EMBL:AF034780 xref: EMBL:AY262688 xref: EMBL:BC069598 xref: HGNC:HGNC:3169 xref: UniGene:Hs.655405 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054727 ! S1PR2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022626 name: S1PR3_human def: "Sphingosine 1-phosphate receptor 3 gene" [UniProtKB:Q99500] synonym: "EDG3" EXACT [UniProtKB:Q99500] xref: EMBL:AF022139 xref: EMBL:AK312798 xref: EMBL:AL772202 xref: EMBL:AY322540 xref: EMBL:BC060827 xref: EMBL:BC069579 xref: EMBL:CH471089 xref: EMBL:X83864 xref: HGNC:HGNC:3167 xref: UniGene:Hs.585118 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058418 ! S1PR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022627 name: S1PR4_human def: "Sphingosine 1-phosphate receptor 4 gene" [UniProtKB:O95977] synonym: "EDG6" EXACT [UniProtKB:O95977] xref: EMBL:AJ000479 xref: EMBL:AY322537 xref: EMBL:BC014970 xref: HGNC:HGNC:3170 xref: UniGene:Hs.662006 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054813 ! S1PR4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022628 name: S1PR5_human def: "Sphingosine 1-phosphate receptor 5 gene" [UniProtKB:Q9H228] synonym: "EDG8" EXACT [UniProtKB:Q9H228] xref: EMBL:AB083602 xref: EMBL:AC011461 xref: EMBL:AF317676 xref: EMBL:AF331840 xref: EMBL:AK074661 xref: EMBL:AY262689 xref: EMBL:BC034703 xref: EMBL:BC067781 xref: HGNC:HGNC:14299 xref: UniGene:Hs.501561 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058673 ! S1PR5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022629 name: SLC22A24_human def: "Solute carrier family 22 member 24 gene" [UniProtKB:Q8N4F4] xref: EMBL:BC034394 xref: HGNC:HGNC:28542 xref: UniGene:Hs.375139 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062774 ! S22AO_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022630 name: SLC25A38_human def: "Solute carrier family 25 member 38 gene" [UniProtKB:Q96DW6] xref: EMBL:AK000558 xref: EMBL:BC013194 xref: EMBL:CR457242 xref: HGNC:HGNC:26054 xref: UniGene:Hs.369615 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063495 ! S2538_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022631 name: SLC35E1_human def: "Solute carrier family 35 member E1 gene" [UniProtKB:Q96K37] synonym: "PSEC0038" EXACT [UniProtKB:Q96K37] xref: EMBL:AK027699 xref: EMBL:AK027850 xref: EMBL:AK075355 xref: EMBL:BC014557 xref: EMBL:BC062562 xref: EMBL:BX640756 xref: HGNC:HGNC:20803 xref: UniGene:Hs.585896 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063513 ! S35E1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022632 name: SLC38A3_human def: "Sodium-coupled neutral amino acid transporter 3 gene" [UniProtKB:Q99624] synonym: "G17" EXACT [UniProtKB:Q99624] synonym: "NAT1" EXACT [UniProtKB:Q99624] synonym: "SN1" EXACT [UniProtKB:Q99624] synonym: "SNAT3" EXACT [UniProtKB:Q99624] xref: EMBL:AC002077 xref: EMBL:AF244548 xref: EMBL:BC042875 xref: EMBL:BX537382 xref: EMBL:CR456970 xref: EMBL:U49082 xref: HGNC:HGNC:18044 xref: UniGene:Hs.76460 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063485 ! S38A3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022633 name: UBA2_human def: "SUMO-activating enzyme subunit 2 gene" [UniProtKB:Q9UBT2] synonym: "HRIHFB2115" EXACT [UniProtKB:Q9UBT2] synonym: "SAE2" EXACT [UniProtKB:Q9UBT2] synonym: "UBLE1B" EXACT [UniProtKB:Q9UBT2] xref: EMBL:AB015337 xref: EMBL:AB208872 xref: EMBL:AF079566 xref: EMBL:AF090384 xref: EMBL:AF110957 xref: EMBL:AL136905 xref: EMBL:BC003153 xref: EMBL:BT009781 xref: EMBL:CR456756 xref: EMBL:U35832 xref: HGNC:HGNC:30661 xref: UniGene:Hs.631580 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063247 ! SAE2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022634 name: SAMM50_human def: "Sorting and assembly machinery component 50 homolog gene" [UniProtKB:Q9Y512] synonym: "CGI-51" EXACT [UniProtKB:Q9Y512] xref: EMBL:AF151809 xref: EMBL:AK001087 xref: EMBL:AL035398 xref: EMBL:BC007830 xref: EMBL:BC011681 xref: EMBL:BC015200 xref: EMBL:CR456483 xref: HGNC:HGNC:24276 xref: UniGene:Hs.505824 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062893 ! SAM50_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022635 name: SAPS2_human def: "SAPS domain family member 2 gene" [UniProtKB:O75170] synonym: "KIAA0685" EXACT [UniProtKB:O75170] xref: EMBL:AB014585 xref: EMBL:AL096767 xref: EMBL:AL671545 xref: EMBL:AL954743 xref: EMBL:BC000976 xref: HGNC:HGNC:19253 xref: UniGene:Hs.449098 xref: UniGene:Hs.699390 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063315 ! SAPS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022636 name: PSAP_human def: "Proactivator polypeptide precursor gene" [UniProtKB:P07602] synonym: "GLBA" EXACT [UniProtKB:P07602] synonym: "SAP1" EXACT [UniProtKB:P07602] xref: EMBL:BC001503 xref: EMBL:BC004275 xref: EMBL:BC007612 xref: EMBL:CR456746 xref: EMBL:D00422 xref: EMBL:J03015 xref: EMBL:J03077 xref: EMBL:M12710 xref: EMBL:M32221 xref: EMBL:M60255 xref: EMBL:M60257 xref: EMBL:M60258 xref: EMBL:M86181 xref: EMBL:X57107 xref: EMBL:X57108 xref: HGNC:HGNC:9498 xref: UniGene:Hs.523004 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063292 ! SAP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022637 name: SEC16A_human def: "Protein transport protein Sec16A gene" [UniProtKB:O15027] synonym: "KIAA0310" EXACT [UniProtKB:O15027] synonym: "SEC16" EXACT [UniProtKB:O15027] synonym: "SEC16L" EXACT [UniProtKB:O15027] xref: EMBL:AB002308 xref: EMBL:AL592301 xref: EMBL:BC008332 xref: EMBL:BC028183 xref: EMBL:DQ903855 xref: HGNC:HGNC:29006 xref: UniGene:Hs.522500 xref: UniGene:Hs.705608 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063119 ! SC16A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022638 name: SCO2_human def: "Protein SCO2 homolog, mitochondrial precursor gene" [UniProtKB:O43819] xref: EMBL:AF177385 xref: EMBL:AL021683 xref: EMBL:BC102024 xref: EMBL:BC102025 xref: EMBL:CR456569 xref: HGNC:HGNC:10604 xref: UniGene:Hs.592212 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063102 ! SCO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022639 name: SCARB1_human def: "Scavenger receptor class B member 1 gene" [UniProtKB:Q8WTV0] synonym: "CD36L1" EXACT [UniProtKB:Q8WTV0] synonym: "CLA1" EXACT [UniProtKB:Q8WTV0] xref: EMBL:AF515445 xref: EMBL:BC022087 xref: EMBL:BC080647 xref: EMBL:Z22555 xref: HGNC:HGNC:1664 xref: UniGene:Hs.520348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063229 ! SCRB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022640 name: PHGDH_human def: "D-3-phosphoglycerate dehydrogenase gene" [UniProtKB:O43175] synonym: "PGDH3" EXACT [UniProtKB:O43175] xref: EMBL:AF006043 xref: EMBL:AF171237 xref: EMBL:AL139251 xref: EMBL:AL589734 xref: EMBL:BC000303 xref: EMBL:BC001349 xref: EMBL:BC011262 xref: EMBL:CR456795 xref: HGNC:HGNC:8923 xref: UniGene:Hs.487296 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063100 ! SERA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022641 name: PSAT1_human def: "Phosphoserine aminotransferase gene" [UniProtKB:Q9Y617] synonym: "PSA" EXACT [UniProtKB:Q9Y617] xref: EMBL:AF113132 xref: EMBL:BC000971 xref: EMBL:BC004863 xref: EMBL:BC016645 xref: EMBL:BC018129 xref: EMBL:BT006840 xref: HGNC:HGNC:19129 xref: UniGene:Hs.494261 xref: UniGene:Hs.592595 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063180 ! SERC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022642 name: SERP2_human def: "Stress-associated endoplasmic reticulum protein 2 gene" [UniProtKB:Q8N6R1] synonym: "C13orf21" EXACT [UniProtKB:Q8N6R1] xref: EMBL:AL138960 xref: EMBL:BC029067 xref: HGNC:HGNC:20607 xref: UniGene:Hs.377972 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062906 ! SERP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022643 name: SERPINH1_human def: "Serpin H1 precursor gene" [UniProtKB:P50454] synonym: "CBP1" EXACT [UniProtKB:P50454] synonym: "CBP2" EXACT [UniProtKB:P50454] synonym: "HSP47" EXACT [UniProtKB:P50454] synonym: "PIG14" EXACT [UniProtKB:P50454] synonym: "SERPINH2" EXACT [UniProtKB:P50454] xref: EMBL:AB044778 xref: EMBL:AB044779 xref: EMBL:AY264853 xref: EMBL:AY744367 xref: EMBL:BC014623 xref: EMBL:BC036298 xref: EMBL:BC070087 xref: EMBL:BT007094 xref: EMBL:D83174 xref: EMBL:X61598 xref: HGNC:HGNC:1546 xref: UniGene:Hs.596449 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063363 ! SERPH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022644 name: SF3B4_human def: "Splicing factor 3B subunit 4 gene" [UniProtKB:Q15427] synonym: "SAP49" EXACT [UniProtKB:Q15427] xref: EMBL:BC004273 xref: EMBL:BC013886 xref: EMBL:L35013 xref: HGNC:HGNC:10771 xref: UniGene:Hs.516160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062935 ! SF3B4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022645 name: SFRS14_human def: "Putative splicing factor, arginine/serine-rich 14 gene" [UniProtKB:Q8IX01] synonym: "KIAA0365" EXACT [UniProtKB:Q8IX01] xref: EMBL:AB002363 xref: EMBL:AC004447 xref: EMBL:AF518874 xref: EMBL:AL832488 xref: EMBL:BC020586 xref: EMBL:BX647813 xref: HGNC:HGNC:18641 xref: UniGene:Hs.515271 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063335 ! SFR14_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022646 name: SFRS16_human def: "Splicing factor, arginine/serine-rich 16 gene" [UniProtKB:Q8N2M8] synonym: "SWAP2" EXACT [UniProtKB:Q8N2M8] synonym: "UNQ2428/PRO4988" EXACT [UniProtKB:Q8N2M8] xref: EMBL:AF042800 xref: EMBL:AF042802 xref: EMBL:AF042803 xref: EMBL:AF042804 xref: EMBL:AF042805 xref: EMBL:AF042806 xref: EMBL:AF042807 xref: EMBL:AF042808 xref: EMBL:AF042809 xref: EMBL:AF042810 xref: EMBL:AK074590 xref: EMBL:AY358944 xref: EMBL:BC013178 xref: EMBL:BC080554 xref: HGNC:HGNC:17731 xref: UniGene:Hs.466917 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062947 ! SFR16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022647 name: SFRS2_human def: "Splicing factor, arginine/serine-rich 2 gene" [UniProtKB:Q01130] xref: EMBL:BC000339 xref: EMBL:BC001303 xref: EMBL:BC070086 xref: EMBL:BT007250 xref: EMBL:L03693 xref: EMBL:M90104 xref: EMBL:X62447 xref: EMBL:X75755 xref: HGNC:HGNC:10783 xref: UniGene:Hs.584801 xref: UniGene:Hs.700144 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063030 ! SFRS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022648 name: SFRS5_human def: "Splicing factor, arginine/serine-rich 5 gene" [UniProtKB:Q13243] synonym: "HRS" EXACT [UniProtKB:Q13243] synonym: "SRP40" EXACT [UniProtKB:Q13243] xref: EMBL:AF020307 xref: EMBL:BC018823 xref: EMBL:BC040209 xref: EMBL:BT007089 xref: EMBL:U30826 xref: EMBL:U30827 xref: EMBL:U30884 xref: HGNC:HGNC:10787 xref: UniGene:Hs.632326 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031760 ! SFRS5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022649 name: SFXN1_human def: "Sideroflexin-1 gene" [UniProtKB:Q9H9B4] xref: EMBL:AF327346 xref: EMBL:AK022287 xref: EMBL:AK022938 xref: EMBL:BC020517 xref: EMBL:BC063241 xref: HGNC:HGNC:16085 xref: UniGene:Hs.369440 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063062 ! SFXN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022650 name: SFXN3_human def: "Sideroflexin-3 gene" [UniProtKB:Q9BWM7] xref: EMBL:AK074707 xref: EMBL:AL133215 xref: EMBL:BC000124 xref: HGNC:HGNC:16087 xref: UniGene:Hs.283844 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062990 ! SFXN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022651 name: SH3BGRL2_human def: "SH3 domain-binding glutamic acid-rich-like protein 2 gene" [UniProtKB:Q9UJC5] synonym: "FASH3" EXACT [UniProtKB:Q9UJC5] xref: EMBL:AF340151 xref: EMBL:AJ297972 xref: EMBL:AL035700 xref: EMBL:AL451064 xref: HGNC:HGNC:15567 xref: UniGene:Hs.302772 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063200 ! SH3L2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022652 name: SIRPA_human def: "Tyrosine-protein phosphatase non-receptor type substrate 1 precursor gene" [UniProtKB:P78324] synonym: "BIT" EXACT [UniProtKB:P78324] synonym: "MFR" EXACT [UniProtKB:P78324] synonym: "MYD1" EXACT [UniProtKB:P78324] synonym: "PTPNS1" EXACT [UniProtKB:P78324] synonym: "SHPS1" EXACT [UniProtKB:P78324] synonym: "SIRP" EXACT [UniProtKB:P78324] xref: EMBL:AB023430 xref: EMBL:AC004832 xref: EMBL:AL034562 xref: EMBL:AL117335 xref: EMBL:BC026692 xref: EMBL:BC033092 xref: EMBL:BC038510 xref: EMBL:BC075849 xref: EMBL:D86043 xref: EMBL:Y10375 xref: EMBL:Y11047 xref: HGNC:HGNC:9662 xref: UniGene:Hs.581021 xref: UniGene:Hs.679042 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062831 ! SHPS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022653 name: ST6GALNAC6_human def: "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 gene" [UniProtKB:Q969X2] synonym: "SIAT7F" EXACT [UniProtKB:Q969X2] synonym: "UNQ708/PRO1359" EXACT [UniProtKB:Q969X2] xref: EMBL:AB035173 xref: EMBL:AJ507293 xref: EMBL:AK023900 xref: EMBL:AL157935 xref: EMBL:AY358672 xref: EMBL:BC006564 xref: EMBL:BC007802 xref: EMBL:BC016299 xref: EMBL:CH471090 xref: EMBL:CR457318 xref: HGNC:HGNC:23364 xref: UniGene:Hs.109672 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063336 ! SIA7F_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022654 name: NANS_human def: "Sialic acid synthase gene" [UniProtKB:Q9NR45] synonym: "SAS" EXACT [UniProtKB:Q9NR45] xref: EMBL:AF257466 xref: EMBL:AK001659 xref: EMBL:AL137073 xref: EMBL:BC000008 xref: EMBL:BC019315 xref: HGNC:HGNC:19237 xref: UniGene:Hs.522310 xref: UniGene:Hs.665191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063186 ! SIAS_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022655 name: MAPKAP1_human def: "Target of rapamycin complex 2 subunit MAPKAP1 gene" [UniProtKB:Q9BPZ7] synonym: "MIP1" EXACT [UniProtKB:Q9BPZ7] synonym: "SIN1" EXACT [UniProtKB:Q9BPZ7] xref: EMBL:AK290060 xref: EMBL:AL162584 xref: EMBL:AL359632 xref: EMBL:AL833042 xref: EMBL:AY524429 xref: EMBL:AY524430 xref: EMBL:AY524431 xref: EMBL:AY524432 xref: EMBL:AY633624 xref: EMBL:AY633625 xref: EMBL:AY633626 xref: EMBL:BC002326 xref: EMBL:BC003044 xref: EMBL:CH471090 xref: EMBL:M37191 xref: HGNC:HGNC:18752 xref: UniGene:Hs.495138 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027730 ! SIN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022656 name: SLPI_human def: "Antileukoproteinase precursor gene" [UniProtKB:P03973] synonym: "WAP4" EXACT [UniProtKB:P03973] synonym: "WFDC4" EXACT [UniProtKB:P03973] xref: EMBL:AF114471 xref: EMBL:AL035660 xref: EMBL:BC020708 xref: EMBL:X04470 xref: EMBL:X04502 xref: EMBL:X04503 xref: HGNC:HGNC:11092 xref: UniGene:Hs.517070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063044 ! SLPI_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022657 name: SGMS1_human def: "Phosphatidylcholine:ceramide cholinephosphotransferase 1 gene" [UniProtKB:Q86VZ5] synonym: "MOB" EXACT [UniProtKB:Q86VZ5] synonym: "SMS1" EXACT [UniProtKB:Q86VZ5] synonym: "TMEM23" EXACT [UniProtKB:Q86VZ5] xref: EMBL:AB154421 xref: EMBL:AK026683 xref: EMBL:AY280959 xref: EMBL:AY312431 xref: EMBL:AY332650 xref: EMBL:AY364088 xref: EMBL:BC042899 xref: EMBL:BN000143 xref: HGNC:HGNC:29799 xref: UniGene:Hs.654698 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063311 ! SMS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022658 name: SMYD3_human def: "SET and MYND domain-containing protein 3 gene" [UniProtKB:Q9H7B4] synonym: "ZMYND1" EXACT [UniProtKB:Q9H7B4] synonym: "ZNFN3A1" EXACT [UniProtKB:Q9H7B4] xref: EMBL:AB057595 xref: EMBL:AK024733 xref: EMBL:AL356583 xref: EMBL:AL358859 xref: EMBL:AL445468 xref: EMBL:AL512412 xref: EMBL:AY186742 xref: EMBL:BC017079 xref: EMBL:BC031010 xref: EMBL:CH471148 xref: HGNC:HGNC:15513 xref: UniGene:Hs.567571 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063274 ! SMYD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022659 name: NAPA_human def: "Alpha-soluble NSF attachment protein gene" [UniProtKB:P54920] synonym: "SNAPA" EXACT [UniProtKB:P54920] xref: EMBL:BC001165 xref: EMBL:BC007432 xref: EMBL:BC028234 xref: EMBL:BC091511 xref: EMBL:BT019568 xref: EMBL:U39412 xref: HGNC:HGNC:7641 xref: UniGene:Hs.126938 xref: UniGene:Hs.700763 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062917 ! SNAA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022660 name: SNAP23_human def: "Synaptosomal-associated protein 23 gene" [UniProtKB:O00161] xref: EMBL:AJ011915 xref: EMBL:AJ278972 xref: EMBL:AJ278973 xref: EMBL:AJ278974 xref: EMBL:BC000148 xref: EMBL:BC003686 xref: EMBL:BC022890 xref: EMBL:BT006916 xref: EMBL:CR457212 xref: EMBL:U55936 xref: EMBL:Y09567 xref: EMBL:Y09568 xref: HGNC:HGNC:11131 xref: UniGene:Hs.511149 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062858 ! SNP23_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022661 name: SNRPA_human def: "U1 small nuclear ribonucleoprotein A gene" [UniProtKB:P09012] xref: EMBL:BC000405 xref: EMBL:BC008290 xref: EMBL:M60779 xref: EMBL:M60780 xref: EMBL:M60781 xref: EMBL:M60782 xref: EMBL:M60783 xref: EMBL:M60784 xref: EMBL:X06347 xref: HGNC:HGNC:11151 xref: UniGene:Hs.466775 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063003 ! SNRPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022662 name: SNTA1_human def: "Alpha-1-syntrophin gene" [UniProtKB:Q13424] synonym: "SNT1" EXACT [UniProtKB:Q13424] xref: EMBL:AL355392 xref: EMBL:BC026215 xref: EMBL:S81737 xref: EMBL:U40571 xref: HGNC:HGNC:11167 xref: UniGene:Hs.31121 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063265 ! SNTA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022663 name: SNTB1_human def: "Beta-1-syntrophin gene" [UniProtKB:Q13884] synonym: "SNT2B1" EXACT [UniProtKB:Q13884] xref: EMBL:AF028828 xref: EMBL:BC098573 xref: EMBL:L31529 xref: HGNC:HGNC:11168 xref: UniGene:Hs.655236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063266 ! SNTB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022664 name: SNTB2_human def: "Beta-2-syntrophin gene" [UniProtKB:Q13425] synonym: "D16S2531E" EXACT [UniProtKB:Q13425] synonym: "SNT2B2" EXACT [UniProtKB:Q13425] synonym: "SNTL" EXACT [UniProtKB:Q13425] xref: EMBL:AF243385 xref: EMBL:BC048215 xref: EMBL:U40572 xref: HGNC:HGNC:11169 xref: UniGene:Hs.461117 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063299 ! SNTB2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022665 name: SNX18_human def: "Sorting nexin-18 gene" [UniProtKB:Q96RF0] synonym: "SH3PXD3B" EXACT [UniProtKB:Q96RF0] synonym: "SNAG1" EXACT [UniProtKB:Q96RF0] xref: EMBL:AF395536 xref: EMBL:BC060791 xref: EMBL:BC067860 xref: EMBL:BC117218 xref: EMBL:BC117220 xref: EMBL:CH471123 xref: HGNC:HGNC:19245 xref: UniGene:Hs.432755 xref: UniGene:Hs.606166 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063241 ! SNX18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022666 name: SNX24_human def: "Sorting nexin-24 gene" [UniProtKB:Q9Y343] synonym: "SBBI31" EXACT [UniProtKB:Q9Y343] synonym: "UNQ654/PRO1284" EXACT [UniProtKB:Q9Y343] xref: EMBL:AF139461 xref: EMBL:AY044655 xref: EMBL:AY358098 xref: EMBL:BC010886 xref: EMBL:BC069012 xref: HGNC:HGNC:21533 xref: UniGene:Hs.483200 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063535 ! SNX24_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022667 name: SNX4_human def: "Sorting nexin-4 gene" [UniProtKB:O95219] xref: EMBL:AF065485 xref: EMBL:BC018762 xref: HGNC:HGNC:11175 xref: UniGene:Hs.507243 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063208 ! SNX4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022668 name: SORL1_human def: "Sortilin-related receptor precursor gene" [UniProtKB:Q92673] xref: EMBL:U60975 xref: EMBL:Y08110 xref: HGNC:HGNC:11185 xref: UniGene:Hs.368592 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063198 ! SORL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022669 name: SPATA2_human def: "Spermatogenesis-associated protein 2 gene" [UniProtKB:Q9UM82] synonym: "KIAA0757" EXACT [UniProtKB:Q9UM82] synonym: "PD1" EXACT [UniProtKB:Q9UM82] xref: EMBL:AB018300 xref: EMBL:AL031685 xref: EMBL:BC009481 xref: EMBL:U28164 xref: HGNC:HGNC:14681 xref: UniGene:Hs.48513 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062808 ! SPAT2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022670 name: SPRN_human def: "Shadow of prion protein precursor gene" [UniProtKB:Q5BIV9] synonym: "SHO" EXACT [UniProtKB:Q5BIV9] xref: EMBL:BC040198 xref: EMBL:BN000518 xref: HGNC:HGNC:16871 xref: UniGene:Hs.64968 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063491 ! SPRN_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022671 name: SPRR3_human def: "Small proline-rich protein 3 gene" [UniProtKB:Q9UBC9] synonym: "SPRC" EXACT [UniProtKB:Q9UBC9] xref: EMBL:AF077374 xref: EMBL:AJ243667 xref: EMBL:AL356867 xref: EMBL:AY118269 xref: EMBL:BC017802 xref: EMBL:DQ017955 xref: HGNC:HGNC:11268 xref: UniGene:Hs.139322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063041 ! SPRR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022672 name: SPTA1_human def: "Spectrin alpha chain, erythrocyte gene" [UniProtKB:P02549] synonym: "SPTA" EXACT [UniProtKB:P02549] xref: EMBL:M11049 xref: EMBL:M13233 xref: EMBL:M29983 xref: EMBL:M29984 xref: EMBL:M29985 xref: EMBL:M29986 xref: EMBL:M29987 xref: EMBL:M29988 xref: EMBL:M29989 xref: EMBL:M29990 xref: EMBL:M29991 xref: EMBL:M29992 xref: EMBL:M29993 xref: EMBL:M29994 xref: EMBL:M61776 xref: EMBL:M61777 xref: EMBL:M61778 xref: EMBL:M61779 xref: EMBL:M61780 xref: EMBL:M61781 xref: EMBL:M61782 xref: EMBL:M61783 xref: EMBL:M61784 xref: EMBL:M61785 xref: EMBL:M61787 xref: EMBL:M61788 xref: EMBL:M61789 xref: EMBL:M61791 xref: EMBL:M61792 xref: EMBL:M61793 xref: EMBL:M61794 xref: EMBL:M61795 xref: EMBL:M61796 xref: EMBL:M61797 xref: EMBL:M61798 xref: EMBL:M61799 xref: EMBL:M61800 xref: EMBL:M61801 xref: EMBL:M61802 xref: EMBL:M61803 xref: EMBL:M61804 xref: EMBL:M61805 xref: EMBL:M61806 xref: EMBL:M61807 xref: EMBL:M61808 xref: EMBL:M61809 xref: EMBL:M61810 xref: EMBL:M61811 xref: EMBL:M61812 xref: EMBL:M61814 xref: EMBL:M61815 xref: EMBL:M61816 xref: EMBL:M61817 xref: EMBL:M61818 xref: EMBL:M61819 xref: EMBL:M61820 xref: EMBL:M61821 xref: EMBL:M61822 xref: EMBL:M61823 xref: EMBL:M61824 xref: EMBL:M61825 xref: EMBL:M61826 xref: EMBL:M61852 xref: EMBL:M61877 xref: HGNC:HGNC:11272 xref: UniGene:Hs.119825 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063212 ! SPTA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022673 name: SPRY2_human def: "Protein sprouty homolog 2 gene" [UniProtKB:O43597] xref: EMBL:AF039843 xref: EMBL:AL354668 xref: EMBL:AL713749 xref: EMBL:BC015745 xref: HGNC:HGNC:11270 xref: UniGene:Hs.18676 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062871 ! SPY2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022674 name: AGXT_human def: "Serine--pyruvate aminotransferase gene" [UniProtKB:P21549] synonym: "AGT1" EXACT [UniProtKB:P21549] synonym: "SPAT" EXACT [UniProtKB:P21549] xref: EMBL:D13368 xref: EMBL:M61763 xref: EMBL:X53414 xref: EMBL:X56092 xref: HGNC:HGNC:341 xref: UniGene:Hs.144567 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063534 ! SPYA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022675 name: SQRDL_human def: "Sulfide:quinone oxidoreductase, mitochondrial precursor gene" [UniProtKB:Q9Y6N5] synonym: "CGI-44" EXACT [UniProtKB:Q9Y6N5] xref: EMBL:AF042284 xref: EMBL:AF151802 xref: EMBL:BC016836 xref: HGNC:HGNC:20390 xref: UniGene:Hs.511251 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063211 ! SQRD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022676 name: SR140_human def: "U2-associated protein SR140 gene" [UniProtKB:O15042] synonym: "KIAA0332" EXACT [UniProtKB:O15042] xref: EMBL:AB002330 xref: EMBL:AC018450 xref: EMBL:AC026304 xref: EMBL:BC006474 xref: EMBL:BC016323 xref: EMBL:BC105604 xref: EMBL:BC111692 xref: EMBL:BK000564 xref: UniGene:Hs.596572 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063169 ! SR140_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022677 name: CTTN_human def: "Src substrate cortactin gene" [UniProtKB:Q14247] synonym: "EMS1" EXACT [UniProtKB:Q14247] xref: EMBL:AP000487 xref: EMBL:M98343 xref: HGNC:HGNC:3338 xref: UniGene:Hs.632133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063370 ! SRC8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022678 name: SSBP4_human def: "Single-stranded DNA-binding protein 4 gene" [UniProtKB:Q9BWG4] xref: EMBL:BC000274 xref: HGNC:HGNC:15676 xref: UniGene:Hs.405873 xref: UniGene:Hs.515259 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062821 ! SSBP4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022679 name: SSR4_human def: "Translocon-associated protein subunit delta precursor gene" [UniProtKB:P51571] synonym: "TRAPD" EXACT [UniProtKB:P51571] xref: EMBL:BC003371 xref: EMBL:BT007192 xref: EMBL:U52111 xref: EMBL:X90583 xref: EMBL:Z68129 xref: EMBL:Z69043 xref: HGNC:HGNC:11326 xref: UniGene:Hs.409223 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063081 ! SSRD_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022680 name: STAM2_human def: "Signal transducing adapter molecule 2 gene" [UniProtKB:O75886] synonym: "HBP" EXACT [UniProtKB:O75886] xref: EMBL:AC079790 xref: EMBL:AF042273 xref: EMBL:AF042274 xref: EMBL:AL133600 xref: EMBL:BC028740 xref: HGNC:HGNC:11358 xref: UniGene:Hs.17200 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062916 ! STAM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022681 name: STARD9_human def: "StAR-related lipid transfer protein 9 gene" [UniProtKB:Q9P2P6] synonym: "KIAA1300" EXACT [UniProtKB:Q9P2P6] xref: EMBL:AB037721 xref: EMBL:AC018362 xref: EMBL:AC090510 xref: EMBL:AK122666 xref: EMBL:AL133579 xref: EMBL:CR627426 xref: EMBL:CR749416 xref: HGNC:HGNC:19162 xref: UniGene:Hs.122061 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063448 ! STAR9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022682 name: STT3A_human def: "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A gene" [UniProtKB:P46977] synonym: "ITM1" EXACT [UniProtKB:P46977] synonym: "TMC" EXACT [UniProtKB:P46977] xref: EMBL:AK290040 xref: EMBL:AK290657 xref: EMBL:BC020965 xref: EMBL:BC048348 xref: EMBL:BT007100 xref: EMBL:CH471065 xref: EMBL:L38961 xref: EMBL:L47337 xref: HGNC:HGNC:6172 xref: UniGene:Hs.504237 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063449 ! STT3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022683 name: STX8_human def: "Syntaxin-8 gene" [UniProtKB:Q9UNK0] xref: EMBL:AF036715 xref: EMBL:AF062077 xref: EMBL:AF115323 xref: EMBL:BC009713 xref: HGNC:HGNC:11443 xref: UniGene:Hs.431109 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062787 ! STX8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022684 name: STXBP1_human def: "Syntaxin-binding protein 1 gene" [UniProtKB:P61764] synonym: "UNC18A" EXACT [UniProtKB:P61764] xref: EMBL:AF004562 xref: EMBL:AF004563 xref: EMBL:BC015749 xref: EMBL:D63851 xref: HGNC:HGNC:11444 xref: UniGene:Hs.288229 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063301 ! STXB1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022685 name: SUMO2_human def: "Small ubiquitin-related modifier 2 precursor gene" [UniProtKB:P61956] synonym: "SMT3B" EXACT [UniProtKB:P61956] synonym: "SMT3H2" EXACT [UniProtKB:P61956] xref: EMBL:AC005000 xref: EMBL:BC008450 xref: EMBL:BC016775 xref: EMBL:BC022340 xref: EMBL:BC062713 xref: EMBL:BC068465 xref: EMBL:BC070159 xref: EMBL:BC071645 xref: EMBL:BC071646 xref: EMBL:BC107853 xref: EMBL:L76416 xref: EMBL:X99585 xref: HGNC:HGNC:11125 xref: UniGene:Hs.380973 xref: UniGene:Hs.546298 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063001 ! SUMO2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022686 name: SUMO3_human def: "Small ubiquitin-related modifier 3 precursor gene" [UniProtKB:P55854] synonym: "SMT3A" EXACT [UniProtKB:P55854] synonym: "SMT3H1" EXACT [UniProtKB:P55854] xref: EMBL:AK222591 xref: EMBL:BC000036 xref: EMBL:BC008420 xref: EMBL:BT007008 xref: EMBL:CR542173 xref: EMBL:CR542188 xref: EMBL:X99584 xref: HGNC:HGNC:11124 xref: UniGene:Hs.474005 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063000 ! SUMO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022687 name: SURF2_human def: "Surfeit locus protein 2 gene" [UniProtKB:Q15527] xref: EMBL:BC014411 xref: EMBL:Z35094 xref: HGNC:HGNC:11475 xref: UniGene:Hs.159448 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063529 ! SURF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022688 name: AARS_human def: "Alanyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:P49588] xref: EMBL:AC012184 xref: EMBL:AK222824 xref: EMBL:BC011451 xref: EMBL:CH471241 xref: EMBL:D32050 xref: HGNC:HGNC:20 xref: UniGene:Hs.315137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063185 ! SYAC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022689 name: EPRS_human def: "Bifunctional aminoacyl-tRNA synthetase gene" [UniProtKB:P07814] synonym: "GLNS" EXACT [UniProtKB:P07814] synonym: "PARS" EXACT [UniProtKB:P07814] synonym: "PIG32" EXACT [UniProtKB:P07814] synonym: "QARS" EXACT [UniProtKB:P07814] synonym: "QPRS" EXACT [UniProtKB:P07814] xref: EMBL:AY493416 xref: EMBL:BC015494 xref: EMBL:BC034797 xref: EMBL:BC046156 xref: EMBL:BC058921 xref: EMBL:BC126275 xref: EMBL:CR933648 xref: EMBL:X07466 xref: EMBL:X54326 xref: HGNC:HGNC:3418 xref: UniGene:Hs.497788 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063046 ! SYEP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022690 name: HARS_human def: "Histidyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:P12081] synonym: "HRS" EXACT [UniProtKB:P12081] xref: EMBL:BC011807 xref: EMBL:BC080514 xref: EMBL:M96646 xref: EMBL:U18936 xref: EMBL:X05345 xref: EMBL:Z11518 xref: HGNC:HGNC:4816 xref: UniGene:Hs.528050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063195 ! SYHC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022691 name: IARS_human def: "Isoleucyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:P41252] xref: EMBL:AL136097 xref: EMBL:D28473 xref: EMBL:U04953 xref: HGNC:HGNC:5330 xref: UniGene:Hs.445403 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063045 ! SYIC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022692 name: LARS_human def: "Leucyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:Q9P2J5] synonym: "KIAA1352" EXACT [UniProtKB:Q9P2J5] xref: EMBL:AB037773 xref: EMBL:D84223 xref: HGNC:HGNC:6512 xref: UniGene:Hs.432674 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063072 ! SYLC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022693 name: MARS_human def: "Methionyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:P56192] xref: EMBL:AK222767 xref: EMBL:BC002384 xref: EMBL:BC006328 xref: EMBL:BC011639 xref: EMBL:BC011849 xref: EMBL:BC015011 xref: EMBL:BT007338 xref: EMBL:D84224 xref: EMBL:X94754 xref: EMBL:Z49216 xref: HGNC:HGNC:6898 xref: UniGene:Hs.632707 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063060 ! SYMC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022694 name: SYN1_human def: "Synapsin-1 gene" [UniProtKB:P17600] xref: EMBL:AL009172 xref: EMBL:M55301 xref: EMBL:M58321 xref: EMBL:M58341 xref: EMBL:M58351 xref: EMBL:M58353 xref: EMBL:M58359 xref: EMBL:M58371 xref: EMBL:M58372 xref: EMBL:M58373 xref: EMBL:M58374 xref: EMBL:M58375 xref: EMBL:M58376 xref: EMBL:M58377 xref: EMBL:M58378 xref: EMBL:Z84466 xref: HGNC:HGNC:11494 xref: UniGene:Hs.225936 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063435 ! SYN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022695 name: NARS_human def: "Asparaginyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:O43776] synonym: "ASNS" EXACT [UniProtKB:O43776] xref: EMBL:AJ000334 xref: EMBL:AK222835 xref: EMBL:BC001687 xref: EMBL:D84273 xref: HGNC:HGNC:7643 xref: UniGene:Hs.465224 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063332 ! SYNC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022696 name: RARS_human def: "Arginyl-tRNA synthetase, cytoplasmic gene" [UniProtKB:P54136] xref: EMBL:BC000528 xref: EMBL:BC014619 xref: EMBL:BT007394 xref: EMBL:S80343 xref: HGNC:HGNC:9870 xref: UniGene:Hs.654907 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063058 ! SYRC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022697 name: VARS_human def: "Valyl-tRNA synthetase gene" [UniProtKB:P26640] synonym: "G7A" EXACT [UniProtKB:P26640] synonym: "VARS2" EXACT [UniProtKB:P26640] xref: EMBL:AF134726 xref: EMBL:AL662834 xref: EMBL:AL662899 xref: EMBL:AL671762 xref: EMBL:BA000025 xref: EMBL:BC012808 xref: EMBL:M98326 xref: EMBL:X59303 xref: HGNC:HGNC:12651 xref: UniGene:Hs.520026 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063057 ! SYVC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022698 name: TM4SF1_human def: "Transmembrane 4 L6 family member 1 gene" [UniProtKB:P30408] synonym: "M3S1" EXACT [UniProtKB:P30408] synonym: "TAAL6" EXACT [UniProtKB:P30408] xref: EMBL:BC008442 xref: EMBL:BC010166 xref: EMBL:CR456953 xref: EMBL:M90657 xref: HGNC:HGNC:11853 xref: UniGene:Hs.351316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063389 ! T4S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022699 name: MAP3K7IP3_human def: "Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 gene" [UniProtKB:Q8N5C8] synonym: "TAB3" EXACT [UniProtKB:Q8N5C8] xref: EMBL:AY331591 xref: EMBL:AY331592 xref: EMBL:AY371491 xref: EMBL:AY437560 xref: EMBL:BC032526 xref: HGNC:HGNC:30681 xref: UniGene:Hs.188256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063243 ! TAB3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022700 name: TACSTD1_human def: "Tumor-associated calcium signal transducer 1 precursor gene" [UniProtKB:P16422] synonym: "GA733-2" EXACT [UniProtKB:P16422] synonym: "M1S2" EXACT [UniProtKB:P16422] synonym: "M4S1" EXACT [UniProtKB:P16422] synonym: "MIC18" EXACT [UniProtKB:P16422] synonym: "TROP1" EXACT [UniProtKB:P16422] xref: EMBL:AC079775 xref: EMBL:BC014785 xref: EMBL:CH471053 xref: EMBL:CR542259 xref: EMBL:CR542283 xref: EMBL:M26481 xref: EMBL:M32306 xref: EMBL:M32325 xref: EMBL:M33011 xref: EMBL:M93029 xref: EMBL:M93030 xref: EMBL:M93031 xref: EMBL:M93032 xref: EMBL:M93033 xref: EMBL:M93034 xref: EMBL:M93035 xref: EMBL:M93036 xref: EMBL:X14758 xref: HGNC:HGNC:11529 xref: UniGene:Hs.699160 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063205 ! TACD1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022701 name: TARDBP_human def: "TAR DNA-binding protein 43 gene" [UniProtKB:Q13148] synonym: "TDP43" EXACT [UniProtKB:Q13148] xref: EMBL:AL050265 xref: EMBL:AL109811 xref: EMBL:BC071657 xref: EMBL:BC095435 xref: EMBL:CR533534 xref: EMBL:U23731 xref: HGNC:HGNC:11571 xref: UniGene:Hs.300624 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063162 ! TADBP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022702 name: TUBA4B_human def: "Putative tubulin-like protein alpha-4B gene" [UniProtKB:Q9H853] synonym: "TUBA4" EXACT [UniProtKB:Q9H853] xref: EMBL:AC068946 xref: EMBL:AK024002 xref: HGNC:HGNC:18637 xref: UniGene:Hs.664469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063064 ! TBA4B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022703 name: CCT1_human def: "T-complex protein 1 subunit alpha gene" [UniProtKB:P17987] synonym: "CCTA" EXACT [UniProtKB:P17987] synonym: "TCP1" EXACT [UniProtKB:P17987] xref: EMBL:AL135914 xref: EMBL:BC000665 xref: EMBL:BT006969 xref: EMBL:M26885 xref: EMBL:M26889 xref: EMBL:M27272 xref: EMBL:X52882 xref: HGNC:HGNC:11655 xref: UniGene:Hs.363137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063080 ! TCPA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022704 name: CCT6A_human def: "T-complex protein 1 subunit zeta gene" [UniProtKB:P40227] synonym: "CCT6" EXACT [UniProtKB:P40227] synonym: "CCTZ" EXACT [UniProtKB:P40227] xref: EMBL:AB063318 xref: EMBL:AC092101 xref: EMBL:AC092579 xref: EMBL:AF385084 xref: EMBL:BC106942 xref: EMBL:L27706 xref: EMBL:M94083 xref: HGNC:HGNC:1620 xref: UniGene:Hs.82916 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063086 ! TCPZ_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022705 name: TESC_human def: "Tescalcin gene" [UniProtKB:Q96BS2] xref: EMBL:AC026368 xref: EMBL:AF443207 xref: EMBL:AK000614 xref: EMBL:BC015221 xref: EMBL:CH471054 xref: HGNC:HGNC:26065 xref: UniGene:Hs.525709 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062775 ! TESC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022706 name: TESK1_human def: "Dual specificity testis-specific protein kinase 1 gene" [UniProtKB:Q15569] xref: EMBL:AL357874 xref: EMBL:BC038448 xref: EMBL:BC067130 xref: EMBL:CH471071 xref: EMBL:D50863 xref: HGNC:HGNC:11731 xref: UniGene:Hs.699324 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063231 ! TESK1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022707 name: TEX28_human def: "Testis-specific protein TEX28 gene" [UniProtKB:O15482] synonym: "CXorf2" EXACT [UniProtKB:O15482] xref: EMBL:AC092402 xref: EMBL:BC026183 xref: EMBL:CH471172 xref: EMBL:U93720 xref: EMBL:Z46936 xref: EMBL:Z68193 xref: HGNC:HGNC:2563 xref: UniGene:Hs.115365 xref: UniGene:Hs.662202 xref: UniGene:Hs.672606 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062964 ! TEX28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022708 name: TFRC_human def: "Transferrin receptor protein 1 gene" [UniProtKB:P02786] xref: EMBL:AB209254 xref: EMBL:AF187320 xref: EMBL:BC001188 xref: EMBL:M11507 xref: EMBL:X01060 xref: HGNC:HGNC:11763 xref: UniGene:Hs.529618 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063056 ! TFR1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022709 name: QTRT1_human def: "Queuine tRNA-ribosyltransferase gene" [UniProtKB:Q9BXR0] synonym: "TGT" EXACT [UniProtKB:Q9BXR0] synonym: "TGUT" EXACT [UniProtKB:Q9BXR0] xref: EMBL:AF302783 xref: EMBL:AF302784 xref: EMBL:BC015350 xref: HGNC:HGNC:23797 xref: UniGene:Hs.631638 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063429 ! TGT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022710 name: THAP1_human def: "THAP domain-containing protein 1 gene" [UniProtKB:Q9NVV9] xref: EMBL:AK001339 xref: EMBL:AK223231 xref: EMBL:BC021721 xref: EMBL:CR457256 xref: HGNC:HGNC:20856 xref: UniGene:Hs.7432 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062880 ! THAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022711 name: THEG_human def: "Testicular haploid expressed gene" [UniProtKB:Q9P2T0] xref: EMBL:AB033129 xref: EMBL:AC016588 xref: EMBL:AF268610 xref: EMBL:BC028574 xref: EMBL:CH471242 xref: HGNC:HGNC:13706 xref: UniGene:Hs.250002 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062946 ! THEG_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022712 name: THOC7_human def: "THO complex subunit 7 homolog gene" [UniProtKB:Q6I9Y2] synonym: "NIF3L1BP1" EXACT [UniProtKB:Q6I9Y2] xref: EMBL:AK027098 xref: EMBL:BC020599 xref: EMBL:BC065012 xref: EMBL:CH471055 xref: EMBL:CR457373 xref: HGNC:HGNC:29874 xref: UniGene:Hs.288151 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063425 ! THOC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022713 name: THSD7A_human def: "Thrombospondin type-1 domain-containing protein 7A precursor gene" [UniProtKB:Q9UPZ6] synonym: "KIAA0960" EXACT [UniProtKB:Q9UPZ6] xref: EMBL:AB023177 xref: EMBL:AK092252 xref: HGNC:HGNC:22207 xref: UniGene:Hs.120855 xref: UniGene:Hs.648482 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063152 ! THS7A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022714 name: TIFA_human def: "TRAF-interacting protein with FHA domain-containing protein A gene" [UniProtKB:Q96CG3] synonym: "T2BP" EXACT [UniProtKB:Q96CG3] xref: EMBL:AB062110 xref: EMBL:AB097011 xref: EMBL:AB097038 xref: EMBL:AC109347 xref: EMBL:AK292900 xref: EMBL:BC014259 xref: EMBL:CH471057 xref: HGNC:HGNC:19075 xref: UniGene:Hs.310640 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062825 ! TIFA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022715 name: TIMM44_human def: "Mitochondrial import inner membrane translocase subunit TIM44 precursor gene" [UniProtKB:O43615] synonym: "MIMT44" EXACT [UniProtKB:O43615] synonym: "TIM44" EXACT [UniProtKB:O43615] xref: EMBL:AF041254 xref: EMBL:BC033628 xref: HGNC:HGNC:17316 xref: UniGene:Hs.465784 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063251 ! TIM44_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022716 name: TINAGL1_human def: "Tubulointerstitial nephritis antigen-like precursor gene" [UniProtKB:Q9GZM7] synonym: "GIS5" EXACT [UniProtKB:Q9GZM7] synonym: "LCN7" EXACT [UniProtKB:Q9GZM7] synonym: "OLRG2" EXACT [UniProtKB:Q9GZM7] synonym: "PP6614" EXACT [UniProtKB:Q9GZM7] synonym: "PSEC0088" EXACT [UniProtKB:Q9GZM7] synonym: "TINAGL" EXACT [UniProtKB:Q9GZM7] synonym: "UNQ204/PRO230" EXACT [UniProtKB:Q9GZM7] xref: EMBL:AB050716 xref: EMBL:AB050719 xref: EMBL:AF205436 xref: EMBL:AF236150 xref: EMBL:AF236151 xref: EMBL:AF236152 xref: EMBL:AF236153 xref: EMBL:AF236154 xref: EMBL:AF236155 xref: EMBL:AF289569 xref: EMBL:AK027839 xref: EMBL:AK074124 xref: EMBL:AK075398 xref: EMBL:AY358421 xref: EMBL:BC009048 xref: EMBL:BC064633 xref: HGNC:HGNC:19168 xref: UniGene:Hs.199368 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0027449 ! TINAL_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022717 name: TMEM147_human def: "Transmembrane protein 147 gene" [UniProtKB:Q9BVK8] xref: EMBL:BC001118 xref: EMBL:Y18007 xref: HGNC:HGNC:30414 xref: UniGene:Hs.9234 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062839 ! TM147_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022718 name: TMEM216_human def: "Transmembrane protein 216 gene" [UniProtKB:Q9P0N5] synonym: "HSPC244" EXACT [UniProtKB:Q9P0N5] xref: EMBL:AF151078 xref: EMBL:AP003108 xref: EMBL:BC011010 xref: EMBL:CR457166 xref: HGNC:HGNC:25018 xref: UniGene:Hs.26745 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063471 ! TM216_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022719 name: TMED10_human def: "Transmembrane emp24 domain-containing protein 10 precursor gene" [UniProtKB:P49755] synonym: "TMP21" EXACT [UniProtKB:P49755] xref: EMBL:AC007055 xref: EMBL:AJ004913 xref: EMBL:AL832012 xref: EMBL:BC001496 xref: EMBL:BC001825 xref: EMBL:BX248754 xref: EMBL:L40397 xref: EMBL:U61734 xref: EMBL:X97442 xref: EMBL:X97444 xref: HGNC:HGNC:16998 xref: UniGene:Hs.74137 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063015 ! TMEDA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022720 name: TMLHE_human def: "Trimethyllysine dioxygenase, mitochondrial precursor gene" [UniProtKB:Q9NVH6] synonym: "TMLH" EXACT [UniProtKB:Q9NVH6] xref: EMBL:AF373407 xref: EMBL:AK001589 xref: EMBL:AM393196 xref: EMBL:BC025269 xref: EMBL:BX276110 xref: EMBL:CR457265 xref: HGNC:HGNC:18308 xref: UniGene:Hs.133321 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0023090 ! TMLH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022721 name: TMEM22_human def: "Transmembrane protein 22 gene" [UniProtKB:Q8TBE7] xref: EMBL:AL136661 xref: EMBL:BC000111 xref: EMBL:BC022557 xref: HGNC:HGNC:28480 xref: UniGene:Hs.655019 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063538 ! TMM22_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022722 name: TMEM33_human def: "Transmembrane protein 33 gene" [UniProtKB:P57088] synonym: "DB83" EXACT [UniProtKB:P57088] xref: EMBL:AK001387 xref: EMBL:AK023062 xref: EMBL:BC000948 xref: EMBL:CR457260 xref: HGNC:HGNC:25541 xref: UniGene:Hs.31082 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063256 ! TMM33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022723 name: TMEM51_human def: "Transmembrane protein 51 gene" [UniProtKB:Q9NW97] synonym: "C1orf72" EXACT [UniProtKB:Q9NW97] xref: EMBL:AK001061 xref: EMBL:AL391094 xref: EMBL:BC000202 xref: EMBL:BC000593 xref: EMBL:CR457120 xref: HGNC:HGNC:25488 xref: UniGene:Hs.465305 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063522 ! TMM51_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022724 name: TMOD3_human def: "Tropomodulin-3 gene" [UniProtKB:Q9NYL9] xref: EMBL:AF177171 xref: EMBL:AF237631 xref: EMBL:AL137543 xref: EMBL:BC020542 xref: HGNC:HGNC:11873 xref: UniGene:Hs.4998 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063097 ! TMOD3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022725 name: TMPRSS3_human def: "Transmembrane protease, serine 3 gene" [UniProtKB:P57727] synonym: "ECHOS1" EXACT [UniProtKB:P57727] synonym: "TADG12" EXACT [UniProtKB:P57727] synonym: "UNQ323/PRO382" EXACT [UniProtKB:P57727] xref: EMBL:AB038157 xref: EMBL:AB038158 xref: EMBL:AB038159 xref: EMBL:AB038160 xref: EMBL:AF201380 xref: EMBL:AK172842 xref: EMBL:AY358458 xref: EMBL:BC074846 xref: EMBL:BC074847 xref: HGNC:HGNC:11877 xref: UniGene:Hs.208600 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063390 ! TMPS3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022726 name: TOM1_human def: "Target of Myb protein 1 gene" [UniProtKB:O60784] xref: EMBL:AJ006973 xref: EMBL:AL008635 xref: EMBL:CR456595 xref: EMBL:Z82244 xref: HGNC:HGNC:11982 xref: UniGene:Hs.474705 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063278 ! TOM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022727 name: C18orf10_human def: "Tubulin polyglutamylase complex subunit 2 gene" [UniProtKB:Q68CL5] synonym: "HMFN0601" EXACT [UniProtKB:Q68CL5] synonym: "L17" EXACT [UniProtKB:Q68CL5] xref: EMBL:AB073382 xref: EMBL:AL050225 xref: EMBL:AY598336 xref: EMBL:BC015178 xref: EMBL:BC022199 xref: EMBL:BC087845 xref: HGNC:HGNC:24561 xref: UniGene:Hs.695999 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062881 ! TPGS2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022728 name: TPM1_human def: "Tropomyosin alpha-1 chain gene" [UniProtKB:P09493] synonym: "C15orf13" EXACT [UniProtKB:P09493] synonym: "TMSA" EXACT [UniProtKB:P09493] xref: EMBL:BC007433 xref: EMBL:BC050473 xref: EMBL:M19267 xref: EMBL:M19713 xref: EMBL:M19714 xref: EMBL:M19715 xref: EMBL:X12369 xref: HGNC:HGNC:12010 xref: UniGene:Hs.133892 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063369 ! TPM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022729 name: TPM2_human def: "Tropomyosin beta chain gene" [UniProtKB:P07951] synonym: "TMSB" EXACT [UniProtKB:P07951] xref: EMBL:AF209746 xref: EMBL:AK223258 xref: EMBL:AL133410 xref: EMBL:BC011776 xref: EMBL:CH471071 xref: EMBL:J05247 xref: EMBL:M12125 xref: EMBL:M12126 xref: EMBL:M74817 xref: EMBL:M75165 xref: EMBL:X06825 xref: HGNC:HGNC:12011 xref: UniGene:Hs.300772 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063362 ! TPM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022730 name: TPM3_human def: "Tropomyosin alpha-3 chain gene" [UniProtKB:P06753] xref: EMBL:AL590431 xref: EMBL:AY004867 xref: EMBL:BC000771 xref: EMBL:BC008407 xref: EMBL:BC008425 xref: EMBL:BC015403 xref: EMBL:BC072428 xref: EMBL:X03541 xref: EMBL:X04201 xref: EMBL:X04588 xref: HGNC:HGNC:12012 xref: UniGene:Hs.535581 xref: UniGene:Hs.654421 xref: UniGene:Hs.705387 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063054 ! TPM3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022731 name: TNFRSF10C_human def: "Tumor necrosis factor receptor superfamily member 10C precursor gene" [UniProtKB:O14798] synonym: "DCR1" EXACT [UniProtKB:O14798] synonym: "LIT" EXACT [UniProtKB:O14798] synonym: "TRAILR3" EXACT [UniProtKB:O14798] synonym: "TRID" EXACT [UniProtKB:O14798] synonym: "UNQ321/PRO366" EXACT [UniProtKB:O14798] xref: EMBL:AF012536 xref: EMBL:AF012629 xref: EMBL:AF014794 xref: EMBL:AF016267 xref: EMBL:AF020502 xref: EMBL:AF033854 xref: EMBL:AY358281 xref: EMBL:BC125041 xref: EMBL:BC125042 xref: EMBL:CR541857 xref: HGNC:HGNC:11906 xref: UniGene:Hs.655801 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063436 ! TR10C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022732 name: TRIM11_human def: "Tripartite motif-containing protein 11 gene" [UniProtKB:Q96F44] synonym: "RNF92" EXACT [UniProtKB:Q96F44] xref: EMBL:AF220125 xref: EMBL:AF327056 xref: EMBL:AK074866 xref: EMBL:AL670729 xref: EMBL:BC011629 xref: EMBL:BC069227 xref: HGNC:HGNC:16281 xref: UniGene:Hs.13543 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063350 ! TRI11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022733 name: TRIM16_human def: "Tripartite motif-containing protein 16 gene" [UniProtKB:O95361] synonym: "EBBP" EXACT [UniProtKB:O95361] xref: EMBL:AF096870 xref: EMBL:BC001564 xref: EMBL:BC053514 xref: EMBL:BC067096 xref: HGNC:HGNC:17241 xref: UniGene:Hs.123534 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063539 ! TRI16_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022734 name: TRIM31_human def: "Tripartite motif-containing protein 31 gene" [UniProtKB:Q9BZY9] synonym: "C6orf13" EXACT [UniProtKB:Q9BZY9] synonym: "RNF" EXACT [UniProtKB:Q9BZY9] xref: EMBL:AF230386 xref: EMBL:AF230387 xref: EMBL:AK222729 xref: EMBL:AL669914 xref: EMBL:AL671859 xref: EMBL:BC016866 xref: EMBL:BC017017 xref: EMBL:BT006675 xref: EMBL:BX322644 xref: EMBL:Y07828 xref: HGNC:HGNC:16289 xref: UniGene:Hs.493275 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062874 ! TRI31_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022735 name: TRIM32_human def: "Tripartite motif-containing protein 32 gene" [UniProtKB:Q13049] synonym: "HT2A" EXACT [UniProtKB:Q13049] xref: EMBL:AL133284 xref: EMBL:BC003154 xref: EMBL:U18543 xref: HGNC:HGNC:16380 xref: UniGene:Hs.591910 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062794 ! TRI32_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022736 name: TRIM41_human def: "Tripartite motif-containing protein 41 gene" [UniProtKB:Q8WV44] xref: EMBL:AB063180 xref: EMBL:AB100366 xref: EMBL:AB100367 xref: EMBL:AF258579 xref: EMBL:BC004956 xref: EMBL:BC009762 xref: EMBL:BC018765 xref: EMBL:BC071887 xref: EMBL:BC090953 xref: EMBL:CR457349 xref: HGNC:HGNC:19013 xref: UniGene:Hs.441488 xref: UniGene:Hs.700303 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062904 ! TRI41_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022737 name: TRIM2_human def: "Tripartite motif-containing protein 2 gene" [UniProtKB:Q9C040] synonym: "KIAA0517" EXACT [UniProtKB:Q9C040] synonym: "RNF86" EXACT [UniProtKB:Q9C040] xref: EMBL:AB011089 xref: EMBL:AF220018 xref: EMBL:AL110234 xref: EMBL:BC005016 xref: EMBL:BC011052 xref: HGNC:HGNC:15974 xref: UniGene:Hs.435711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063196 ! TRIM2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022738 name: TRIP12_human def: "Probable E3 ubiquitin-protein ligase TRIP12 gene" [UniProtKB:Q14669] synonym: "KIAA0045" EXACT [UniProtKB:Q14669] xref: EMBL:D28476 xref: EMBL:L40383 xref: HGNC:HGNC:12306 xref: UniGene:Hs.591633 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062992 ! TRIPC_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022739 name: TRM61_human def: "tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61 gene" [UniProtKB:Q96FX7] synonym: "C14orf172" EXACT [UniProtKB:Q96FX7] xref: EMBL:AK097771 xref: EMBL:AL133367 xref: EMBL:BC010167 xref: HGNC:HGNC:23790 xref: UniGene:Hs.525610 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063283 ! TRM61_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022740 name: TRPC3_human def: "Short transient receptor potential channel 3 gene" [UniProtKB:Q13507] synonym: "TRP3" EXACT [UniProtKB:Q13507] xref: EMBL:BC093682 xref: EMBL:BC093684 xref: EMBL:U47050 xref: EMBL:X89068 xref: EMBL:Y13758 xref: HGNC:HGNC:12335 xref: UniGene:Hs.150981 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063192 ! TRPC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022741 name: TRPC6_human def: "Short transient receptor potential channel 6 gene" [UniProtKB:Q9Y210] synonym: "TRP6" EXACT [UniProtKB:Q9Y210] xref: EMBL:AF080394 xref: EMBL:AJ006276 xref: EMBL:AJ007018 xref: EMBL:AJ271066 xref: EMBL:AJ271067 xref: EMBL:AJ271068 xref: EMBL:BC093658 xref: EMBL:BC093660 xref: HGNC:HGNC:12338 xref: UniGene:Hs.159003 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062980 ! TRPC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022742 name: TRPC7_human def: "Short transient receptor potential channel 7 gene" [UniProtKB:Q9HCX4] synonym: "TRP7" EXACT [UniProtKB:Q9HCX4] xref: EMBL:AJ272034 xref: HGNC:HGNC:20754 xref: UniGene:Hs.591263 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063351 ! TRPC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022743 name: TSPAN3_human def: "Tetraspanin-3 gene" [UniProtKB:O60637] synonym: "TM4SF8" EXACT [UniProtKB:O60637] xref: EMBL:AF054840 xref: EMBL:AF133423 xref: EMBL:AK001305 xref: EMBL:AK001310 xref: EMBL:AK001326 xref: EMBL:BC000704 xref: EMBL:BC004280 xref: EMBL:BC009248 xref: EMBL:BC011206 xref: HGNC:HGNC:17752 xref: UniGene:Hs.5062 xref: UniGene:Hs.592528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062933 ! TSN3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022744 name: TSNAX_human def: "Translin-associated protein X gene" [UniProtKB:Q99598] synonym: "TRAX" EXACT [UniProtKB:Q99598] xref: EMBL:AF271267 xref: EMBL:AF271268 xref: EMBL:AF271269 xref: EMBL:BC010376 xref: EMBL:BC011797 xref: EMBL:X95073 xref: HGNC:HGNC:12380 xref: UniGene:Hs.96247 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062792 ! TSNAX_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022745 name: TSSK6_human def: "Testis-specific serine/threonine-protein kinase 6 gene" [UniProtKB:Q9BXA6] synonym: "FKSG82" EXACT [UniProtKB:Q9BXA6] synonym: "SSTK" EXACT [UniProtKB:Q9BXA6] xref: EMBL:AF329483 xref: EMBL:AF348077 xref: EMBL:AK058166 xref: EMBL:AK172841 xref: EMBL:BC014611 xref: HGNC:HGNC:30410 xref: UniGene:Hs.532711 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063300 ! TSSK6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022746 name: TTC19_human def: "Tetratricopeptide repeat protein 19 gene" [UniProtKB:Q6DKK2] xref: EMBL:AC002553 xref: EMBL:AC006251 xref: EMBL:AK000350 xref: EMBL:AK056878 xref: EMBL:BC011698 xref: EMBL:BC073796 xref: EMBL:BC105128 xref: EMBL:BC112107 xref: HGNC:HGNC:26006 xref: UniGene:Hs.462316 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063312 ! TTC19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022747 name: TTC28_human def: "Tetratricopeptide repeat protein 28 gene" [UniProtKB:Q96AY4] synonym: "KIAA1043" EXACT [UniProtKB:Q96AY4] xref: EMBL:AB028966 xref: EMBL:AL008724 xref: EMBL:AL033538 xref: EMBL:AL035453 xref: EMBL:AL050313 xref: EMBL:AL080174 xref: EMBL:AL137328 xref: EMBL:BC016465 xref: HGNC:HGNC:29179 xref: UniGene:Hs.387856 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063150 ! TTC28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022748 name: TTR_human def: "Transthyretin precursor gene" [UniProtKB:P02766] synonym: "PALB" EXACT [UniProtKB:P02766] xref: EMBL:BC005310 xref: EMBL:BC020791 xref: EMBL:BT007189 xref: EMBL:CR456908 xref: EMBL:D00096 xref: EMBL:K02091 xref: EMBL:M10605 xref: EMBL:M11518 xref: EMBL:M11714 xref: EMBL:M11844 xref: EMBL:M15515 xref: EMBL:M15516 xref: EMBL:M15517 xref: EMBL:M63285 xref: EMBL:S63185 xref: EMBL:S72385 xref: EMBL:U19780 xref: EMBL:X59498 xref: HGNC:HGNC:12405 xref: UniGene:Hs.427202 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063374 ! TTHY_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022749 name: IGSF9_human def: "Protein turtle homolog A precursor gene" [UniProtKB:Q9P2J2] synonym: "IGSF9A" EXACT [UniProtKB:Q9P2J2] synonym: "KIAA1355" EXACT [UniProtKB:Q9P2J2] synonym: "NRT1" EXACT [UniProtKB:Q9P2J2] xref: EMBL:AB037776 xref: HGNC:HGNC:18132 xref: UniGene:Hs.591472 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063442 ! TUTLA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022750 name: U2AF1_human def: "Splicing factor U2AF 35 kDa subunit gene" [UniProtKB:Q01081] synonym: "U2AF35" EXACT [UniProtKB:Q01081] synonym: "U2AFBP" EXACT [UniProtKB:Q01081] xref: EMBL:AP001748 xref: EMBL:BC001177 xref: EMBL:BC001923 xref: EMBL:M96982 xref: HGNC:HGNC:12453 xref: UniGene:Hs.365116 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063031 ! U2AF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022751 name: U2AF2_human def: "Splicing factor U2AF 65 kDa subunit gene" [UniProtKB:P26368] synonym: "U2AF65" EXACT [UniProtKB:P26368] xref: EMBL:BC008740 xref: EMBL:BC030574 xref: EMBL:CH471135 xref: EMBL:X64044 xref: HGNC:HGNC:23156 xref: UniGene:Hs.528007 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063011 ! U2AF2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022752 name: EFTUD2_human def: "116 kDa U5 small nuclear ribonucleoprotein component gene" [UniProtKB:Q15029] synonym: "KIAA0031" EXACT [UniProtKB:Q15029] synonym: "SNRP116" EXACT [UniProtKB:Q15029] xref: EMBL:BC002360 xref: EMBL:D21163 xref: HGNC:HGNC:30858 xref: UniGene:Hs.151787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063122 ! U5S1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022753 name: UACA_human def: "Uveal autoantigen with coiled-coil domains and ankyrin repeats gene" [UniProtKB:Q9BZF9] synonym: "KIAA1561" EXACT [UniProtKB:Q9BZF9] xref: EMBL:AB046781 xref: EMBL:AF322916 xref: EMBL:AK000990 xref: EMBL:AL834464 xref: EMBL:BC113407 xref: EMBL:BC113409 xref: HGNC:HGNC:15947 xref: UniGene:Hs.108049 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063038 ! UACA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022754 name: UBA1_human def: "Ubiquitin-like modifier-activating enzyme 1 gene" [UniProtKB:P22314] synonym: "A1S9T" EXACT [UniProtKB:P22314] synonym: "UBE1" EXACT [UniProtKB:P22314] xref: EMBL:AL513366 xref: EMBL:BC013041 xref: EMBL:CH471164 xref: EMBL:M58028 xref: EMBL:X52897 xref: EMBL:X56976 xref: HGNC:HGNC:12469 xref: UniGene:Hs.533273 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063177 ! UBA1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022755 name: UBE2B_human def: "Ubiquitin-conjugating enzyme E2 B gene" [UniProtKB:P63146] synonym: "RAD6B" EXACT [UniProtKB:P63146] xref: EMBL:BC005979 xref: EMBL:BC008404 xref: EMBL:BC008470 xref: EMBL:BT007071 xref: EMBL:CR407634 xref: EMBL:DQ090910 xref: EMBL:M74525 xref: EMBL:X53251 xref: HGNC:HGNC:12473 xref: UniGene:Hs.615284 xref: UniGene:Hs.695927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063391 ! UBE2B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022756 name: UBL4A_human def: "Ubiquitin-like protein 4A gene" [UniProtKB:P11441] synonym: "DXS254E" EXACT [UniProtKB:P11441] synonym: "GDX" EXACT [UniProtKB:P11441] synonym: "UBL4" EXACT [UniProtKB:P11441] xref: EMBL:BC043346 xref: EMBL:BC053589 xref: EMBL:J03589 xref: EMBL:L44140 xref: HGNC:HGNC:12505 xref: UniGene:Hs.76480 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063099 ! UBL4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022757 name: UBL7_human def: "Ubiquitin-like protein 7 gene" [UniProtKB:Q96S82] synonym: "BMSCUBP" EXACT [UniProtKB:Q96S82] synonym: "SB132" EXACT [UniProtKB:Q96S82] xref: EMBL:AY037166 xref: EMBL:BC007913 xref: EMBL:BC030055 xref: EMBL:BC033919 xref: HGNC:HGNC:28221 xref: UniGene:Hs.334713 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062945 ! UBL7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022758 name: USP11_human def: "Ubiquitin carboxyl-terminal hydrolase 11 gene" [UniProtKB:P51784] synonym: "UHX1" EXACT [UniProtKB:P51784] xref: EMBL:AB073597 xref: EMBL:AL096791 xref: EMBL:BC000350 xref: EMBL:U44839 xref: HGNC:HGNC:12609 xref: UniGene:Hs.171501 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063143 ! UBP11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022759 name: USP13_human def: "Ubiquitin carboxyl-terminal hydrolase 13 gene" [UniProtKB:Q92995] synonym: "ISOT3" EXACT [UniProtKB:Q92995] xref: EMBL:BC016146 xref: EMBL:CH471052 xref: EMBL:U75362 xref: HGNC:HGNC:12611 xref: UniGene:Hs.591319 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063494 ! UBP13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022760 name: USP18_human def: "Ubl carboxyl-terminal hydrolase 18 gene" [UniProtKB:Q9UMW8] synonym: "ISG43" EXACT [UniProtKB:Q9UMW8] xref: EMBL:AF176642 xref: EMBL:AJ243526 xref: EMBL:AL136690 xref: EMBL:BC014896 xref: HGNC:HGNC:12616 xref: UniGene:Hs.38260 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063074 ! UBP18_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022761 name: UBAP2L_human def: "Ubiquitin-associated protein 2-like gene" [UniProtKB:Q14157] synonym: "KIAA0144" EXACT [UniProtKB:Q14157] synonym: "NICE4" EXACT [UniProtKB:Q14157] xref: EMBL:AJ243668 xref: EMBL:AJ243670 xref: EMBL:AL590431 xref: EMBL:BC003170 xref: EMBL:D63478 xref: HGNC:HGNC:29877 xref: UniGene:Hs.490551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063327 ! UBP2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022762 name: USP2_human def: "Ubiquitin carboxyl-terminal hydrolase 2 gene" [UniProtKB:O75604] synonym: "UBP41" EXACT [UniProtKB:O75604] xref: EMBL:AF079564 xref: EMBL:AK057225 xref: EMBL:BC002854 xref: EMBL:BC002955 xref: HGNC:HGNC:12618 xref: UniGene:Hs.524085 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062903 ! UBP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022763 name: USP33_human def: "Ubiquitin carboxyl-terminal hydrolase 33 gene" [UniProtKB:Q8TEY7] synonym: "KIAA1097" EXACT [UniProtKB:Q8TEY7] synonym: "VDU1" EXACT [UniProtKB:Q8TEY7] xref: EMBL:AB029020 xref: EMBL:AF383172 xref: EMBL:AF383173 xref: EMBL:AK022864 xref: EMBL:BC016663 xref: HGNC:HGNC:20059 xref: UniGene:Hs.480597 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063468 ! UBP33_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022764 name: UCHL5IP_human def: "UCHL5-interacting protein gene" [UniProtKB:Q99871] synonym: "UIP1" EXACT [UniProtKB:Q99871] xref: EMBL:AF267739 xref: EMBL:BC008141 xref: EMBL:X99270 xref: HGNC:HGNC:32979 xref: UniGene:Hs.170835 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063173 ! UC5IP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022765 name: UGDH_human def: "UDP-glucose 6-dehydrogenase gene" [UniProtKB:O60701] xref: EMBL:AF049126 xref: EMBL:AF061016 xref: EMBL:AJ007702 xref: EMBL:AJ272274 xref: EMBL:AJ272275 xref: EMBL:AJ272276 xref: EMBL:AJ272277 xref: EMBL:AJ272278 xref: EMBL:AJ272279 xref: EMBL:AJ272280 xref: EMBL:AJ272281 xref: EMBL:BC022781 xref: HGNC:HGNC:12525 xref: UniGene:Hs.572518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063357 ! UGDH_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022766 name: UNK_human def: "RING finger protein unkempt homolog gene" [UniProtKB:Q9C0B0] synonym: "KIAA1753" EXACT [UniProtKB:Q9C0B0] synonym: "ZC3H5" EXACT [UniProtKB:Q9C0B0] synonym: "ZC3HDC5" EXACT [UniProtKB:Q9C0B0] xref: EMBL:AB051540 xref: EMBL:BC053362 xref: HGNC:HGNC:29369 xref: UniGene:Hs.584768 xref: UniGene:Hs.655493 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0025523 ! UNK_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022767 name: USO1_human def: "General vesicular transport factor p115 gene" [UniProtKB:O60763] synonym: "VDP" EXACT [UniProtKB:O60763] xref: EMBL:BC006398 xref: EMBL:BC032654 xref: EMBL:D86326 xref: HGNC:HGNC:30904 xref: UniGene:Hs.292689 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063073 ! USO1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022768 name: USP9X_human def: "Probable ubiquitin carboxyl-terminal hydrolase FAF-X gene" [UniProtKB:Q93008] synonym: "DFFRX" EXACT [UniProtKB:Q93008] synonym: "USP9" EXACT [UniProtKB:Q93008] xref: EMBL:AF070645 xref: EMBL:AL109797 xref: EMBL:AL391259 xref: EMBL:X98296 xref: HGNC:HGNC:12632 xref: UniGene:Hs.77578 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063094 ! USP9X_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022769 name: UXT_human def: "Protein UXT gene" [UniProtKB:Q9UBK9] synonym: "HSPC024" EXACT [UniProtKB:Q9UBK9] xref: EMBL:AF083241 xref: EMBL:AF083242 xref: EMBL:AF092737 xref: EMBL:AL009172 xref: EMBL:BC000720 xref: EMBL:BC008890 xref: HGNC:HGNC:12641 xref: UniGene:Hs.172791 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063112 ! UXT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022770 name: ATP6V0D1_human def: "V-type proton ATPase subunit d 1 gene" [UniProtKB:P61421] synonym: "ATP6D" EXACT [UniProtKB:P61421] synonym: "VPATPD" EXACT [UniProtKB:P61421] xref: EMBL:BC008861 xref: EMBL:L05087 xref: EMBL:X71490 xref: HGNC:HGNC:13724 xref: UniGene:Hs.106876 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063214 ! VA0D1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022771 name: ATP6AP1_human def: "V-type proton ATPase subunit S1 precursor gene" [UniProtKB:Q15904] synonym: "ATP6IP1" EXACT [UniProtKB:Q15904] synonym: "ATP6S1" EXACT [UniProtKB:Q15904] synonym: "VATPS1" EXACT [UniProtKB:Q15904] synonym: "XAP3" EXACT [UniProtKB:Q15904] xref: EMBL:AK026519 xref: EMBL:BC000724 xref: EMBL:D16469 xref: EMBL:L44140 xref: HGNC:HGNC:868 xref: UniGene:Hs.6551 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063396 ! VAS1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022772 name: VASP_human def: "Vasodilator-stimulated phosphoprotein gene" [UniProtKB:P50552] xref: EMBL:BC026019 xref: EMBL:BC038224 xref: EMBL:X98533 xref: EMBL:X98534 xref: EMBL:Z46389 xref: HGNC:HGNC:12652 xref: UniGene:Hs.702197 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062884 ! VASP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022773 name: ATP6V1C1_human def: "V-type proton ATPase subunit C 1 gene" [UniProtKB:P21283] synonym: "ATP6C" EXACT [UniProtKB:P21283] synonym: "ATP6D" EXACT [UniProtKB:P21283] synonym: "VATC" EXACT [UniProtKB:P21283] xref: EMBL:AF363578 xref: EMBL:BC010960 xref: EMBL:J05682 xref: EMBL:X69151 xref: HGNC:HGNC:856 xref: UniGene:Hs.86905 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063235 ! VATC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022774 name: ATP6V1E1_human def: "V-type proton ATPase subunit E 1 gene" [UniProtKB:P36543] synonym: "ATP6E" EXACT [UniProtKB:P36543] synonym: "ATP6E2" EXACT [UniProtKB:P36543] xref: EMBL:BC004443 xref: EMBL:CR456385 xref: EMBL:X71491 xref: EMBL:X76228 xref: HGNC:HGNC:857 xref: UniGene:Hs.517338 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0021842 ! VATE1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022775 name: ATP6V0A2_human def: "V-type proton ATPase 116 kDa subunit a isoform 2 gene" [UniProtKB:Q9Y487] xref: EMBL:AF112972 xref: EMBL:AK289391 xref: EMBL:BC068531 xref: EMBL:CH471054 xref: HGNC:HGNC:18481 xref: UniGene:Hs.201939 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063303 ! VPP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022776 name: VPS11_human def: "Vacuolar protein sorting-associated protein 11 homolog gene" [UniProtKB:Q9H270] synonym: "PP3476" EXACT [UniProtKB:Q9H270] synonym: "RNF108" EXACT [UniProtKB:Q9H270] xref: EMBL:AB027508 xref: EMBL:AF258558 xref: EMBL:AF308800 xref: EMBL:AK026012 xref: EMBL:BC012051 xref: EMBL:BC065563 xref: HGNC:HGNC:14583 xref: UniGene:Hs.234282 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063398 ! VPS11_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022777 name: VPS28_human def: "Vacuolar protein sorting-associated protein 28 homolog gene" [UniProtKB:Q9UK41] xref: EMBL:AF182844 xref: EMBL:BC006485 xref: EMBL:BC019321 xref: HGNC:HGNC:18178 xref: UniGene:Hs.418175 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062968 ! VPS28_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022778 name: VPS35_human def: "Vacuolar protein sorting-associated protein 35 gene" [UniProtKB:Q96QK1] synonym: "MEM3" EXACT [UniProtKB:Q96QK1] synonym: "TCCCTA00141" EXACT [UniProtKB:Q96QK1] xref: EMBL:AF175265 xref: EMBL:AF183418 xref: EMBL:AF186382 xref: EMBL:AF191298 xref: EMBL:AK000395 xref: EMBL:AK001614 xref: EMBL:AK023650 xref: EMBL:AL136888 xref: EMBL:AL512769 xref: EMBL:AY007112 xref: EMBL:BC002414 xref: EMBL:BC010362 xref: EMBL:BC093036 xref: HGNC:HGNC:13487 xref: UniGene:Hs.696029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063258 ! VPS35_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022779 name: VPS4A_human def: "Vacuolar protein sorting-associating protein 4A gene" [UniProtKB:Q9UN37] synonym: "VPS4" EXACT [UniProtKB:Q9UN37] xref: EMBL:AF112215 xref: EMBL:AF132747 xref: EMBL:AF155740 xref: EMBL:AF159063 xref: EMBL:AF255952 xref: EMBL:AF282903 xref: EMBL:BC047932 xref: HGNC:HGNC:13488 xref: UniGene:Hs.128420 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062986 ! VPS4A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022780 name: VSTM2L_human def: "V-set and transmembrane domain-containing protein 2-like protein precursor gene" [UniProtKB:Q96N03] synonym: "C20orf102" EXACT [UniProtKB:Q96N03] xref: EMBL:AK056177 xref: EMBL:AL109964 xref: EMBL:AL834410 xref: EMBL:BC033818 xref: HGNC:HGNC:16096 xref: UniGene:Hs.517029 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063305 ! VTM2L_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022781 name: WAS_human def: "Wiskott-Aldrich syndrome protein gene" [UniProtKB:P42768] synonym: "IMD2" EXACT [UniProtKB:P42768] xref: EMBL:AF115549 xref: EMBL:AF196970 xref: EMBL:BC002961 xref: EMBL:BC012738 xref: EMBL:U12707 xref: EMBL:U18935 xref: EMBL:U19927 xref: HGNC:HGNC:12731 xref: UniGene:Hs.2157 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062975 ! WASP_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022782 name: WDR37_human def: "WD repeat-containing protein 37 gene" [UniProtKB:Q9Y2I8] synonym: "KIAA0982" EXACT [UniProtKB:Q9Y2I8] xref: EMBL:AB023199 xref: EMBL:AC022536 xref: EMBL:AL136827 xref: EMBL:AL607085 xref: EMBL:BC018044 xref: HGNC:HGNC:31406 xref: UniGene:Hs.188495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062836 ! Q8WVG2_HUMAN relationship: codes_for CCO:B0063036 ! WDR37_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022783 name: WDR3_human def: "WD repeat-containing protein 3 gene" [UniProtKB:Q9UNX4] xref: EMBL:AF083217 xref: HGNC:HGNC:12755 xref: UniGene:Hs.310809 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063540 ! WDR3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022784 name: WDR68_human def: "WD repeat-containing protein 68 gene" [UniProtKB:P61962] synonym: "HAN11" EXACT [UniProtKB:P61962] xref: EMBL:BC001264 xref: EMBL:U94747 xref: HGNC:HGNC:30915 xref: UniGene:Hs.410596 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0024681 ! WDR68_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022785 name: WDR89_human def: "WD repeat-containing protein 89 gene" [UniProtKB:Q96FK6] synonym: "C14orf150" EXACT [UniProtKB:Q96FK6] synonym: "MSTP050" EXACT [UniProtKB:Q96FK6] xref: EMBL:AF115513 xref: EMBL:AK095324 xref: EMBL:BC010698 xref: EMBL:BX248008 xref: HGNC:HGNC:20489 xref: UniGene:Hs.655666 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063482 ! WDR89_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022786 name: WDTC1_human def: "WD and tetratricopeptide repeats protein 1 gene" [UniProtKB:Q8N5D0] synonym: "KIAA1037" EXACT [UniProtKB:Q8N5D0] xref: EMBL:AB028960 xref: EMBL:AK001734 xref: EMBL:BC032523 xref: HGNC:HGNC:29175 xref: UniGene:Hs.469154 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063155 ! WDTC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022787 name: WIPF1_human def: "WAS/WASL-interacting protein family member 1 gene" [UniProtKB:O43516] synonym: "WASPIP" EXACT [UniProtKB:O43516] synonym: "WIP" EXACT [UniProtKB:O43516] xref: EMBL:AC010894 xref: EMBL:AF031588 xref: EMBL:AF106062 xref: EMBL:BC002914 xref: EMBL:BX640870 xref: EMBL:X86019 xref: HGNC:HGNC:12736 xref: UniGene:Hs.654521 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063008 ! WIPF1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022788 name: WWP2_human def: "NEDD4-like E3 ubiquitin-protein ligase WWP2 gene" [UniProtKB:O00308] xref: EMBL:AC026468 xref: EMBL:BC000108 xref: EMBL:BC013645 xref: EMBL:BC064531 xref: EMBL:CH471092 xref: EMBL:U96114 xref: HGNC:HGNC:16804 xref: UniGene:Hs.408458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062807 ! WWP2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022789 name: XPNPEP3_human def: "Probable Xaa-Pro aminopeptidase 3 gene" [UniProtKB:Q9NQH7] xref: EMBL:AL035450 xref: EMBL:AL365514 xref: EMBL:AL834310 xref: EMBL:BC001208 xref: EMBL:BC001681 xref: EMBL:BC004989 xref: EMBL:CR456442 xref: EMBL:CR457396 xref: EMBL:Z98048 xref: HGNC:HGNC:28052 xref: UniGene:Hs.529163 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063290 ! XPP3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022790 name: XTP3TPA_human def: "XTP3-transactivated gene A protein gene" [UniProtKB:Q9H773] synonym: "CDA03" EXACT [UniProtKB:Q9H773] xref: EMBL:AF210430 xref: EMBL:AF212242 xref: EMBL:AK024843 xref: EMBL:AY453409 xref: EMBL:BC001344 xref: EMBL:CR457335 xref: UniGene:Hs.632191 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062949 ! XTP3A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022791 name: YLPM1_human def: "YLP motif-containing protein 1 gene" [UniProtKB:P49750] synonym: "C14orf170" EXACT [UniProtKB:P49750] synonym: "ZAP3" EXACT [UniProtKB:P49750] xref: EMBL:AC007956 xref: EMBL:BC007792 xref: EMBL:L40400 xref: EMBL:L40403 xref: HGNC:HGNC:17798 xref: UniGene:Hs.531111 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063400 ! YLPM1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022792 name: YY1AP1_human def: "YY1-associated protein 1 gene" [UniProtKB:Q9H869] synonym: "HCCA2" EXACT [UniProtKB:Q9H869] synonym: "YY1AP" EXACT [UniProtKB:Q9H869] xref: EMBL:AF203474 xref: EMBL:AF206328 xref: EMBL:AF466401 xref: EMBL:AK001737 xref: EMBL:AK023976 xref: EMBL:AL162734 xref: EMBL:AY604179 xref: EMBL:BC001655 xref: EMBL:BC001843 xref: EMBL:BC003500 xref: EMBL:BC008766 xref: EMBL:BC009358 xref: EMBL:BC014906 xref: EMBL:BX088689 xref: HGNC:HGNC:30935 xref: UniGene:Hs.584927 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063012 ! YYAP1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022793 name: ZC3H7B_human def: "Zinc finger CCCH domain-containing protein 7B gene" [UniProtKB:Q9UGR2] synonym: "KIAA1031" EXACT [UniProtKB:Q9UGR2] xref: EMBL:AB028954 xref: EMBL:AF188530 xref: EMBL:AK023849 xref: EMBL:AL035659 xref: EMBL:BC024313 xref: HGNC:HGNC:30869 xref: UniGene:Hs.592188 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029451 ! Z3H7B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022794 name: ZNF705G_human def: "Putative zinc finger protein 705G gene" [UniProtKB:A8MUZ8] xref: EMBL:AC130360 xref: EMBL:BE466749 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054051 ! Z705G_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022795 name: ZNF705H_human def: "Putative zinc finger protein 705H gene" [UniProtKB:A8MWA4] xref: EMBL:AP002495 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054077 ! Z705H_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022796 name: ZNF804A_human def: "Zinc finger protein 804A gene" [UniProtKB:Q7Z570] synonym: "C2orf10" EXACT [UniProtKB:Q7Z570] xref: EMBL:AK131402 xref: EMBL:AY327407 xref: HGNC:HGNC:21711 xref: UniGene:Hs.159528 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063306 ! Z804A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022797 name: ZC3H10_human def: "Zinc finger CCCH domain-containing protein 10 gene" [UniProtKB:Q96K80] synonym: "ZC3HDC10" EXACT [UniProtKB:Q96K80] xref: EMBL:AK027357 xref: EMBL:BC018708 xref: HGNC:HGNC:25893 xref: UniGene:Hs.632706 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063216 ! ZC3HA_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022798 name: ZCCHC13_human def: "Zinc finger CCHC domain-containing protein 13 gene" [UniProtKB:Q8WW36] xref: EMBL:BC021176 xref: HGNC:HGNC:31749 xref: UniGene:Hs.157231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063218 ! ZCH13_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022799 name: ZDHHC3_human def: "Palmitoyltransferase ZDHHC3 gene" [UniProtKB:Q9NYG2] synonym: "HSD49" EXACT [UniProtKB:Q9NYG2] synonym: "ZNF373" EXACT [UniProtKB:Q9NYG2] xref: EMBL:AF247703 xref: EMBL:AF441791 xref: EMBL:AY605661 xref: EMBL:BC015467 xref: HGNC:HGNC:18470 xref: UniGene:Hs.61430 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062770 ! ZDHC3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022800 name: ZDHHC7_human def: "Palmitoyltransferase ZDHHC7 gene" [UniProtKB:Q9NXF8] synonym: "ZNF370" EXACT [UniProtKB:Q9NXF8] xref: EMBL:AK000286 xref: EMBL:AK001654 xref: EMBL:BC017702 xref: EMBL:BC018772 xref: HGNC:HGNC:18459 xref: UniGene:Hs.592065 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063275 ! ZDHC7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022801 name: ZFAT_human def: "Zinc finger protein ZFAT gene" [UniProtKB:Q9P243] synonym: "KIAA1485" EXACT [UniProtKB:Q9P243] synonym: "ZFAT1" EXACT [UniProtKB:Q9P243] synonym: "ZNF406" EXACT [UniProtKB:Q9P243] xref: EMBL:AB040918 xref: EMBL:AB167738 xref: EMBL:AB167739 xref: EMBL:AB167740 xref: EMBL:AB167741 xref: EMBL:BC025423 xref: EMBL:BC046180 xref: EMBL:BC101766 xref: EMBL:BC101768 xref: HGNC:HGNC:19899 xref: UniGene:Hs.446172 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059052 ! ZFAT_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022802 name: ZFP82_human def: "Zinc finger protein 82 homolog gene" [UniProtKB:Q8N141] synonym: "KIAA1948" EXACT [UniProtKB:Q8N141] synonym: "ZNF545" EXACT [UniProtKB:Q8N141] xref: EMBL:AB075828 xref: EMBL:AK074942 xref: EMBL:AL834267 xref: EMBL:BC032577 xref: HGNC:HGNC:28682 xref: UniGene:Hs.558734 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057422 ! ZFP82_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022803 name: ZMYND10_human def: "Zinc finger MYND domain-containing protein 10 gene" [UniProtKB:O75800] synonym: "BLU" EXACT [UniProtKB:O75800] synonym: "LUCA12.4" EXACT [UniProtKB:O75800] xref: EMBL:AC002481 xref: EMBL:AL833828 xref: EMBL:BC033732 xref: EMBL:CH471055 xref: EMBL:U70824 xref: EMBL:U70880 xref: HGNC:HGNC:19412 xref: UniGene:Hs.526735 xref: UniGene:Hs.627171 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062863 ! ZMY10_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022804 name: ZMYND19_human def: "Zinc finger MYND domain-containing protein 19 gene" [UniProtKB:Q96E35] synonym: "MIZIP" EXACT [UniProtKB:Q96E35] xref: EMBL:AJ298882 xref: EMBL:AL365502 xref: EMBL:BC012948 xref: HGNC:HGNC:21146 xref: UniGene:Hs.128096 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062896 ! ZMY19_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022805 name: ZNF296_human def: "Zinc finger protein 296 gene" [UniProtKB:Q8WUU4] synonym: "ZNF342" EXACT [UniProtKB:Q8WUU4] xref: EMBL:BC019352 xref: HGNC:HGNC:15981 xref: UniGene:Hs.192237 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057983 ! ZN296_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022806 name: ZNF316_human def: "Zinc finger protein 316 gene" [UniProtKB:A6NFI3] xref: EMBL:AC073343 xref: HGNC:HGNC:13843 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053821 ! ZN316_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022807 name: ZNF330_human def: "Zinc finger protein 330 gene" [UniProtKB:Q9Y3S2] synonym: "NOA36" EXACT [UniProtKB:Q9Y3S2] xref: EMBL:AJ006591 xref: EMBL:AJ404873 xref: EMBL:AJ404874 xref: EMBL:AJ404875 xref: EMBL:AJ404876 xref: EMBL:AJ404877 xref: EMBL:AJ404878 xref: EMBL:AJ404879 xref: EMBL:AJ404880 xref: EMBL:BC004421 xref: HGNC:HGNC:15462 xref: UniGene:Hs.120766 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063163 ! ZN330_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022808 name: ZNF607_human def: "Zinc finger protein 607 gene" [UniProtKB:Q96SK3] xref: EMBL:AK027708 xref: EMBL:BC014850 xref: HGNC:HGNC:28192 xref: UniGene:Hs.334518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062867 ! ZN607_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022809 name: ZNF609_human def: "Zinc finger protein 609 gene" [UniProtKB:O15014] synonym: "KIAA0295" EXACT [UniProtKB:O15014] xref: EMBL:AB002293 xref: EMBL:AC090543 xref: EMBL:BC110401 xref: HGNC:HGNC:29003 xref: UniGene:Hs.595451 xref: UniGene:Hs.683434 xref: UniGene:Hs.696256 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063330 ! ZN609_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022810 name: ZNF638_human def: "Zinc finger protein 638 gene" [UniProtKB:Q14966] synonym: "NP220" EXACT [UniProtKB:Q14966] synonym: "ZFML" EXACT [UniProtKB:Q14966] xref: EMBL:AC007878 xref: EMBL:AC096569 xref: EMBL:AF273049 xref: EMBL:AF534078 xref: EMBL:BC024000 xref: EMBL:BC064530 xref: EMBL:BC083513 xref: EMBL:BX537425 xref: EMBL:CR749322 xref: EMBL:D83032 xref: HGNC:HGNC:17894 xref: UniGene:Hs.434401 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062788 ! ZN638_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022811 name: ZNF716_human def: "Zinc finger protein 716 gene" [UniProtKB:A6NP11] xref: EMBL:AC092175 xref: EMBL:AK131575 xref: HGNC:HGNC:32458 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053923 ! ZN716_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022812 name: ZNF730_human def: "Putative zinc finger protein 730 gene" [UniProtKB:Q6ZMV8] xref: EMBL:AK131472 xref: HGNC:HGNC:32470 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056996 ! ZN730_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022813 name: ZNF732_human def: "Zinc finger protein 732 gene" [UniProtKB:Q49A33] xref: EMBL:AC079140 xref: EMBL:BC046475 xref: HGNC:HGNC:32472 xref: UniGene:Hs.673877 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056297 ! ZN732_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022814 name: ZNF733_human def: "Zinc finger protein 733 gene" [UniProtKB:A6NKZ1] xref: EMBL:AC006455 xref: HGNC:HGNC:32473 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053889 ! ZN733_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022815 name: ZNF734_human def: "Zinc finger protein 734 gene" [UniProtKB:A6NF79] xref: EMBL:AC006457 xref: HGNC:HGNC:32465 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053815 ! ZN734_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022816 name: ZNF735_human def: "Putative zinc finger protein 735 gene" [UniProtKB:A8MUV8] xref: EMBL:AC115220 xref: HGNC:HGNC:32466 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054048 ! ZN735_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022817 name: ZNF834_human def: "Zinc finger protein 834 gene" [UniProtKB:Q9NSJ1] synonym: "PRED65" EXACT [UniProtKB:Q9NSJ1] xref: EMBL:AL163202 xref: HGNC:HGNC:34331 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058921 ! ZN834_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022818 name: ZNF835_human def: "Zinc finger protein 835 gene" [UniProtKB:Q9Y2P0] xref: EMBL:AC007228 xref: EMBL:AK023017 xref: HGNC:HGNC:34332 xref: UniGene:Hs.458438 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0059311 ! ZN835_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022819 name: ZNF836_human def: "Zinc finger protein 836 gene" [UniProtKB:Q6ZNA1] xref: EMBL:AC010320 xref: EMBL:AC011468 xref: EMBL:AK131308 xref: HGNC:HGNC:34333 xref: UniGene:Hs.631584 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057017 ! ZN836_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022820 name: ZNF837_human def: "Zinc finger protein 837 gene" [UniProtKB:Q96EG3] xref: EMBL:BC012365 xref: HGNC:HGNC:25164 xref: UniGene:Hs.222236 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058205 ! ZN837_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022821 name: ZNF841_human def: "Zinc finger protein 841 gene" [UniProtKB:Q6ZN19] xref: EMBL:AK093512 xref: EMBL:AK129938 xref: EMBL:AK131334 xref: EMBL:AK131409 xref: HGNC:HGNC:27611 xref: UniGene:Hs.665751 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0057007 ! ZN841_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022822 name: ZNF844_human def: "Zinc finger protein 844 gene" [UniProtKB:Q08AG5] xref: EMBL:AK098117 xref: EMBL:AL832297 xref: EMBL:BC125186 xref: EMBL:CH471106 xref: HGNC:HGNC:25932 xref: UniGene:Hs.646391 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0055798 ! ZN844_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022823 name: ZNF846_human def: "Zinc finger protein 846 gene" [UniProtKB:Q147U1] xref: EMBL:AC008752 xref: EMBL:AK289536 xref: EMBL:BC118657 xref: HGNC:HGNC:27260 xref: UniGene:Hs.665717 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0056015 ! ZN846_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022824 name: ZNF860_human def: "Zinc finger protein 860 gene" [UniProtKB:A6NHJ4] xref: EMBL:AC108485 xref: EMBL:AK294003 xref: HGNC:HGNC:34513 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053848 ! ZN860_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022825 name: ZNF862_human def: "Zinc finger protein 862 gene" [UniProtKB:O60290] synonym: "KIAA0543" EXACT [UniProtKB:O60290] xref: EMBL:AB011115 xref: EMBL:AC004877 xref: EMBL:BC113087 xref: HGNC:HGNC:34519 xref: UniGene:Hs.301277 xref: UniGene:Hs.632022 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0054541 ! ZN862_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022826 name: ZNF48_human def: "Zinc finger protein 48 gene" [UniProtKB:Q96MX3] synonym: "ZNF553" EXACT [UniProtKB:Q96MX3] xref: EMBL:AK056313 xref: EMBL:AL832433 xref: EMBL:BC007393 xref: EMBL:BC041388 xref: EMBL:M88358 xref: HGNC:HGNC:13114 xref: UniGene:Hs.513501 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058296 ! ZNF48_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022827 name: TJP3_human def: "Tight junction protein ZO-3 gene" [UniProtKB:O95049] synonym: "ZO3" EXACT [UniProtKB:O95049] xref: EMBL:AC005954 xref: EMBL:CH471139 xref: HGNC:HGNC:11829 xref: UniGene:Hs.25527 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063291 ! ZO3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022828 name: ZRANB1_human def: "Zinc finger Ran-binding domain-containing protein 1 gene" [UniProtKB:Q9UGI0] synonym: "TRABID" EXACT [UniProtKB:Q9UGI0] xref: EMBL:AJ252060 xref: EMBL:AL731571 xref: EMBL:AL731577 xref: EMBL:CH471066 xref: HGNC:HGNC:18224 xref: UniGene:Hs.595158 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063027 ! ZRAN1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022829 name: ZSCAN5A_human def: "Zinc finger and SCAN domain-containing protein 5A gene" [UniProtKB:Q9BUG6] synonym: "ZNF495" EXACT [UniProtKB:Q9BUG6] synonym: "ZSCAN5" EXACT [UniProtKB:Q9BUG6] xref: EMBL:AK098700 xref: EMBL:AK223485 xref: EMBL:BC002636 xref: EMBL:BC043232 xref: HGNC:HGNC:23710 xref: UniGene:Hs.177688 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0058520 ! ZSA5A_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022830 name: ZSCAN5B_human def: "Zinc finger and SCAN domain-containing protein 5B gene" [UniProtKB:A6NJL1] xref: EMBL:AC024580 xref: HGNC:HGNC:34246 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053873 ! ZSA5B_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022831 name: ZSCAN5C_human def: "Zinc finger and SCAN domain-containing protein 5C gene" [UniProtKB:A6NGD5] xref: EMBL:AC011506 xref: HGNC:HGNC:34294 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0053831 ! ZSA5C_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022832 name: LKP_human def: "Leukophysin (ATP-dependent RNA helicase A) gene" [UniProtKB:Q12803] synonym: "DHX9" EXACT [UniProtKB:Q12803] xref: EMBL:AB451248 xref: EMBL:AB451372 xref: EMBL:U03643 xref: HGNC:HGNC:2750 xref: UniGene:Hs.191518 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063123 ! Q12803_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022833 name: R3HDM_human def: "Putative uncharacterized protein R3HDM gene" [UniProtKB:Q4ZG59] xref: EMBL:AC011893 xref: HGNC:HGNC:9757 xref: UniGene:Hs.412462 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063326 ! Q4ZG59_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022834 name: NS_human def: "Nucleostemin gene" [UniProtKB:Q5PU80] xref: EMBL:AY825265 xref: HGNC:HGNC:29931 xref: UniGene:Hs.313544 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0016653 ! Q5PU80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022835 name: MRPL42_human def: "MRPL42 protein (Mitochondrial ribosomal protein L42, isoform CRA_b) gene" [UniProtKB:Q6FID1] synonym: "hCG_1647154" EXACT [UniProtKB:Q6FID1] xref: EMBL:CH471054 xref: EMBL:CR533495 xref: HGNC:HGNC:14493 xref: UniGene:Hs.199579 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063420 ! Q6FID1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022836 name: SIAT4C_human def: "SIAT4C protein gene" [UniProtKB:Q6IBE6] synonym: "hCG_37591" EXACT [UniProtKB:Q6IBE6] synonym: "ST3GAL4" EXACT [UniProtKB:Q6IBE6] xref: EMBL:AK314738 xref: EMBL:CH471065 xref: EMBL:CR456858 xref: HGNC:HGNC:10864 xref: UniGene:Hs.591947 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063497 ! Q6IBE6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022837 name: OS-9_human def: "OS-9 protein gene" [UniProtKB:Q6IBL2] xref: EMBL:CR456791 xref: UniGene:Hs.527861 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063512 ! Q6IBL2_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022838 name: U5-116KD_human def: "U5-116KD protein gene" [UniProtKB:Q6IBM8] xref: EMBL:CR456774 xref: HGNC:HGNC:30858 xref: UniGene:Hs.151787 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063437 ! Q6IBM8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022839 name: FLJ10404_human def: "FLJ10404 protein gene" [UniProtKB:Q6IPW0] xref: EMBL:BC071696 xref: UniGene:Hs.484289 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0017183 ! Q6IPW0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022840 name: WDR6_human def: "WDR6 protein gene" [UniProtKB:Q6PKC6] xref: EMBL:BC002826 xref: HGNC:HGNC:12758 xref: UniGene:Hs.654815 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062818 ! Q6PKC6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022841 name: FLJ10842_human def: "Putative uncharacterized protein FLJ10842 gene" [UniProtKB:Q75KN0] xref: EMBL:AC099547 xref: HGNC:HGNC:21869 xref: UniGene:Hs.699361 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063509 ! Q75KN0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022842 name: EMS1_human def: "Cortactin gene" [UniProtKB:Q76MU0] xref: EMBL:AB036705 xref: HGNC:HGNC:3338 xref: UniGene:Hs.632133 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063408 ! Q76MU0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022843 name: SLC35A2_human def: "Solute carrier family 35 (UDP-galactose transporter), member A2 gene" [UniProtKB:Q8IV21] synonym: "hCG_19816" EXACT [UniProtKB:Q8IV21] xref: EMBL:BC035747 xref: EMBL:CH471224 xref: HGNC:HGNC:11022 xref: UniGene:Hs.21899 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062835 ! Q8IV21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022844 name: ELAVL4_human def: "ELAVL4 protein gene" [UniProtKB:Q8IYD4] xref: EMBL:BC036071 xref: HGNC:HGNC:3315 xref: UniGene:Hs.213050 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062921 ! Q8IYD4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022845 name: FBF1_human def: "Fas-binding factor 1. gene" [UniProtKB:Q8IZ48] xref: EMBL:BC023549 xref: HGNC:HGNC:24674 xref: UniGene:Hs.514494 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063492 ! Q8IZ48_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022846 name: TRBC1_human def: "TRBC1 protein gene" [UniProtKB:Q8N2T6] xref: EMBL:BC030533 xref: HGNC:HGNC:12156 xref: UniGene:Hs.654496 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063341 ! Q8N2T6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022847 name: EIF4GI_human def: "Putative regulatory uORF gene" [UniProtKB:Q8NG21] xref: EMBL:AF281070 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063277 ! Q8NG21_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022848 name: DNAJB3_human def: "DnaJ (Hsp40) homolog, subfamily B, member 3 (Putative uncharacterized protein tmp_locus_21) (HCG3 protein) gene" [UniProtKB:Q8WWF6] synonym: "tmp_locus_21" EXACT [UniProtKB:Q8WWF6] xref: EMBL:AC114812 xref: EMBL:AY083665 xref: EMBL:BC017590 xref: EMBL:BC024013 xref: UniGene:Hs.554822 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062801 ! Q8WWF6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022849 name: QK3_human def: "Quaking protein 3 gene" [UniProtKB:Q8WY44] xref: EMBL:AF272349 xref: HGNC:HGNC:21100 xref: UniGene:Hs.510324 xref: UniGene:Hs.593520 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063272 ! Q8WY44_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022850 name: DTNB_human def: "Dystrobrevin, beta gene" [UniProtKB:Q96AW0] synonym: "hCG_23136" EXACT [UniProtKB:Q96AW0] xref: EMBL:BC016655 xref: EMBL:BT009805 xref: EMBL:CH471053 xref: HGNC:HGNC:3058 xref: UniGene:Hs.307720 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0030221 ! Q96AW0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022851 name: QARS_human def: "QARS protein gene" [UniProtKB:Q96AW5] xref: EMBL:BC016634 xref: HGNC:HGNC:9751 xref: UniGene:Hs.79322 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062850 ! Q96AW5_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022852 name: GOLSYN_human def: "cDNA FLJ34055 fis, clone FCBBF3000229, highly similar to Syntabulin gene" [UniProtKB:Q96D80] xref: EMBL:AK091374 xref: EMBL:BC012082 xref: UniGene:Hs.390738 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063310 ! Q96D80_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022853 name: ETNK2_human def: "ETNK2 protein gene" [UniProtKB:Q96G05] synonym: "hCG_16413" EXACT [UniProtKB:Q96G05] synonym: "RP11-74C13.2-001" EXACT [UniProtKB:Q96G05] xref: EMBL:AL592146 xref: EMBL:BC010082 xref: EMBL:CH471067 xref: HGNC:HGNC:25575 xref: UniGene:Hs.497469 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062963 ! Q96G05_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022854 name: ZCCHC14_human def: "Putative uncharacterized protein (ZCCHC14 protein) gene" [UniProtKB:Q96HZ8] xref: EMBL:BC007926 xref: EMBL:BC028304 xref: HGNC:HGNC:24134 xref: UniGene:Hs.156231 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062806 ! Q96HZ8_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022855 name: GPR108_human def: "GPR108 protein gene" [UniProtKB:Q96I30] xref: EMBL:BC007862 xref: HGNC:HGNC:17829 xref: UniGene:Hs.167641 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063511 ! Q96I30_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022856 name: C1orf116_human def: "C1orf116 protein gene" [UniProtKB:Q9BPY1] xref: EMBL:BC001943 xref: HGNC:HGNC:28667 xref: UniGene:Hs.32417 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062952 ! Q9BPY1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022857 name: C18orf45_human def: "C18orf45 protein (Chromosome 18 open reading frame 45) (cDNA, FLJ94820) gene" [UniProtKB:Q9BRG3] synonym: "hCG_2021815" EXACT [UniProtKB:Q9BRG3] xref: EMBL:AK314123 xref: EMBL:BC006280 xref: EMBL:BC054507 xref: EMBL:CH471088 xref: HGNC:HGNC:31723 xref: UniGene:Hs.137562 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062799 ! Q9BRG3_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022858 name: RAP1GDS1_human def: "RAP1, GTP-GDP dissociation stimulator 1 gene" [UniProtKB:Q9BUX6] xref: EMBL:BC001816 xref: EMBL:BC001851 xref: EMBL:BT006837 xref: HGNC:HGNC:9859 xref: UniGene:Hs.132858 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0029859 ! Q9BUX6_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022859 name: mm-1_human def: "MM-1 gamma gene" [UniProtKB:Q9C083] synonym: "hCG_23361" EXACT [UniProtKB:Q9C083] synonym: "PFDN5" EXACT [UniProtKB:Q9C083] xref: EMBL:AB055805 xref: EMBL:CH471054 xref: HGNC:HGNC:8869 xref: UniGene:Hs.655327 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063105 ! Q9C083_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022860 name: DKFZp434D1428_human def: "Putative uncharacterized protein DKFZp434D1428 gene" [UniProtKB:Q9H0E4] xref: EMBL:AL136830 xref: UniGene:Hs.696000 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063451 ! Q9H0E4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022861 name: DKFZp564O0523_human def: "Putative uncharacterized protein DKFZp564O0523 gene" [UniProtKB:Q9H0V7] xref: EMBL:AL136619 xref: UniGene:Hs.21590 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062998 ! Q9H0V7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022862 name: BXDC2_human def: "BRIX gene" [UniProtKB:Q9NUW4] synonym: "BRIX" EXACT [UniProtKB:Q9NUW4] synonym: "hCG_2039716" EXACT [UniProtKB:Q9NUW4] xref: EMBL:AK001962 xref: EMBL:AY364243 xref: EMBL:CH471119 xref: HGNC:HGNC:24170 xref: UniGene:Hs.38114 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063399 ! Q9NUW4_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022863 name: DKFZp434K0435_human def: "Putative uncharacterized protein DKFZp434K0435 gene" [UniProtKB:Q9UFQ0] xref: EMBL:AL117514 xref: HGNC:HGNC:12468 xref: UniGene:Hs.520348 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063117 ! Q9UFQ0_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022864 name: MLP_human def: "Mucin-like protein gene" [UniProtKB:Q9UMI9] xref: EMBL:M86523 xref: HGNC:HGNC:7512 xref: UniGene:Hs.315 xref: UniGene:Hs.647533 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0031883 ! Q9UMI9_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022865 name: HSP70-1_human def: "Heat shock protein 72 gene" [UniProtKB:Q9UQC1] xref: EMBL:AB018045 xref: HGNC:HGNC:5232 xref: UniGene:Hs.520028 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063037 ! Q9UQC1_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022866 name: TRPV6_human def: "DNA-binding protein ABP/ZF (Transient receptor potential cation channel, subfamily V, member 6, isoform CRA_a) (ABP/ZF) (TRPV6 protein) gene" [UniProtKB:Q9Y260] synonym: "hCG_19640" EXACT [UniProtKB:Q9Y260] synonym: "ZFAB" EXACT [UniProtKB:Q9Y260] xref: EMBL:BC034814 xref: EMBL:CH471198 xref: EMBL:U82613 xref: EMBL:X83877 xref: HGNC:HGNC:14006 xref: UniGene:Hs.302740 xref: UniGene:Hs.638966 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0062927 ! Q9Y260_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:G0022867 name: KIAA0864_human def: "KIAA0864 protein gene" [UniProtKB:Q9Y6X7] xref: EMBL:AB020671 xref: UniGene:Hs.462341 is_a: CCO:U0000008 ! cell cycle gene relationship: codes_for CCO:B0063230 ! Q9Y6X7_HUMAN relationship: has_source CCO:T0000004 ! Homo sapiens organism [Term] id: CCO:I0005721 name: cdca3-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002076 ! CDCA3_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0005722 name: lmo2-mapre2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0005171 ! RBTN2_HUMAN [Term] id: CCO:I0005723 name: atf4-gps2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0005172 ! Q96AQ3_HUMAN [Term] id: CCO:I0005724 name: pard6a-prkci physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752629 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0005725 name: tlk1-tlk1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002220 ! TLK1_HUMAN [Term] id: CCO:I0005726 name: qprt-sufu physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005174 ! NADC_HUMAN [Term] id: CCO:I0005727 name: bad-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:I0005728 name: ccnk-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752779 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:I0005729 name: dctn2-gadd45a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001552 ! GA45A_HUMAN relationship: has_participant CCO:B0005177 ! DCTN2_HUMAN [Term] id: CCO:I0005730 name: lzts2-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN [Term] id: CCO:I0005731 name: c8orf32-nme1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0005179 ! CH032_HUMAN [Term] id: CCO:I0005732 name: dazap2-sept2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001800 ! SEPT2_HUMAN relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN [Term] id: CCO:I0005733 name: appl1-dip13b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001980 ! DP13B_HUMAN relationship: has_participant CCO:B0002219 ! DP13A_HUMAN [Term] id: CCO:I0005734 name: ccnh-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0001652 ! CCNH_HUMAN [Term] id: CCO:I0005736 name: c14orf32-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0041276 ! MISSL_HUMAN [Term] id: CCO:I0005737 name: pin1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752986 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0005738 name: fhit-fhit physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001636 ! FHIT_HUMAN [Term] id: CCO:I0005739 name: c18orf24-pldn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753067 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002032 ! SKA1_HUMAN relationship: has_participant CCO:B0005183 ! PLDN_HUMAN [Term] id: CCO:I0005741 name: mageb18-tp53 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005185 ! MAGBI_HUMAN [Term] id: CCO:I0005742 name: c18orf25-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005186 ! CR025_HUMAN [Term] id: CCO:I0005743 name: mad1l1-tex11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753268 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005187 ! TEX11_HUMAN [Term] id: CCO:I0005744 name: ddit3-dhrs10 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0026267 ! DHB14_HUMAN [Term] id: CCO:I0005745 name: pin1-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:I0005746 name: krt18-q9bvr6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0005189 ! Q9BVR6_HUMAN [Term] id: CCO:I0005747 name: loc112869-tada3l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753403 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0058208 ! SGF29_HUMAN [Term] id: CCO:I0005748 name: satb1-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753613 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005191 ! SATB1_HUMAN [Term] id: CCO:I0005749 name: pin1-rai1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753652 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005192 ! RAI1_HUMAN [Term] id: CCO:I0005750 name: lzts2-pak7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0005193 ! Q8TB93_HUMAN [Term] id: CCO:I0005751 name: plekhf2-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753775 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN [Term] id: CCO:I0005752 name: dach1-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005195 ! DACH1_HUMAN [Term] id: CCO:I0005753 name: myo15b-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0005196 ! Q8N374_HUMAN [Term] id: CCO:I0005754 name: ap2b1-mlh1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753892 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0005197 ! AP2B1_HUMAN [Term] id: CCO:I0005755 name: nudcd3-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753934 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005198 ! NUDC3_HUMAN [Term] id: CCO:I0005756 name: hspa2-hspbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753937 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005199 ! HPBP1_HUMAN [Term] id: CCO:I0005757 name: gga2-pin1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753949 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005200 ! GGA2_HUMAN [Term] id: CCO:I0005758 name: glis3-sufu physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005201 ! GLIS3_HUMAN [Term] id: CCO:I0005759 name: fosl1-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754063 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001522 ! FOSL1_HUMAN relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN [Term] id: CCO:I0005760 name: cutc-pim2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754093 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0005203 ! Q96BX3_HUMAN [Term] id: CCO:I0005761 name: mlh1-trim29 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:I0005762 name: lmo2-stat1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0005171 ! RBTN2_HUMAN [Term] id: CCO:I0005763 name: il1f5-mcm6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005205 ! IL1F5_HUMAN [Term] id: CCO:I0005764 name: kntc2-pldn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0005183 ! PLDN_HUMAN [Term] id: CCO:I0005765 name: nme1-nme4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0005206 ! NDKM_HUMAN [Term] id: CCO:I0005766 name: krt15-krt18 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754231 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0005207 ! K1C15_HUMAN [Term] id: CCO:I0005767 name: mgc5356-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754267 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0005208 ! CT195_HUMAN [Term] id: CCO:I0005768 name: fancg-gabpb2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0040683 ! GABP1_HUMAN [Term] id: CCO:I0005769 name: cdkn1a-tex11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754360 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0005187 ! TEX11_HUMAN [Term] id: CCO:I0005770 name: ccnk-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754390 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005210 ! USBP1_HUMAN [Term] id: CCO:I0005771 name: dvl2-mcrs1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754423 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN [Term] id: CCO:I0005773 name: ube2i-znfn1a1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005213 ! IKZF1_HUMAN [Term] id: CCO:I0005774 name: lzts2-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754540 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0005214 ! ZN581_HUMAN [Term] id: CCO:I0005775 name: ccnk-efemp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754681 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN [Term] id: CCO:I0005776 name: ripk2-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754693 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN [Term] id: CCO:I0005777 name: ccnk-kcnrg physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754696 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005217 ! KCNRG_HUMAN [Term] id: CCO:I0005778 name: pin1-zimp7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005218 ! ZMIZ2_HUMAN [Term] id: CCO:I0005779 name: cdk4-cdkn2d physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN [Term] id: CCO:I0005780 name: sept1-sept6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001775 ! SEPT6_HUMAN relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN [Term] id: CCO:I0005781 name: ccnk-fkbp6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005219 ! FKBP6_HUMAN [Term] id: CCO:I0005782 name: ccnk-stx11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754849 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005220 ! STX11_HUMAN [Term] id: CCO:I0005783 name: hist1h3a-nasp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754897 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001626 ! NASP_HUMAN relationship: has_participant CCO:B0005221 ! H31_HUMAN [Term] id: CCO:I0005784 name: ccnk-rfxdc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754903 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0061983 ! RFX6_HUMAN [Term] id: CCO:I0005785 name: mcm7-rbm8a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005223 ! RBM8A_HUMAN [Term] id: CCO:I0005786 name: cdk5r1-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754939 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN relationship: has_participant CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:I0005787 name: plk4-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001348 ! PLK4_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN [Term] id: CCO:I0005788 name: pdlim7-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755017 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005224 ! PDLI7_HUMAN [Term] id: CCO:I0005789 name: hrasls3-ubqln1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755041 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001666 ! HRSL3_HUMAN relationship: has_participant CCO:B0005181 ! UBQL1_HUMAN [Term] id: CCO:I0005790 name: ewsr1-mtcp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755080 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001677 ! MTCPA_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0005791 name: rhebl1-txnl4a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755179 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001702 ! TXN4A_HUMAN relationship: has_participant CCO:B0040684 ! REBL1_HUMAN [Term] id: CCO:I0005792 name: ndp52-shc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755236 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0005793 name: rad54b-znf580 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755269 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005228 ! ZN580_HUMAN [Term] id: CCO:I0005794 name: mark3-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005229 ! MARK3_HUMAN [Term] id: CCO:I0005795 name: ube2i-znf646 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755329 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005230 ! Q8IVD8_HUMAN [Term] id: CCO:I0005796 name: fancg-zbed1x physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0005231 ! ZBED1_HUMAN [Term] id: CCO:I0005797 name: dusp6-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755395 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001824 ! DUS6_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0005798 name: ccnk-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755404 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN [Term] id: CCO:I0005799 name: ccnh-psma1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001652 ! CCNH_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN [Term] id: CCO:I0005801 name: cdc23-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755449 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002260 ! RA54B_HUMAN [Term] id: CCO:I0005802 name: mad2l1-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:I0005803 name: mad1l1-nono physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755521 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005234 ! NONO_HUMAN [Term] id: CCO:I0005804 name: hnrpk-rbm7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002255 ! RBM7_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:I0005805 name: aff4-siah1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001946 ! SIAH1_HUMAN relationship: has_participant CCO:B0005236 ! Q8TAX5_HUMAN [Term] id: CCO:I0005806 name: cdc23-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755605 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN [Term] id: CCO:I0005807 name: dip13b-rab22a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001980 ! DP13B_HUMAN relationship: has_participant CCO:B0005237 ! RB22A_HUMAN [Term] id: CCO:I0005809 name: hnrpc-kras physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755701 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:I0005810 name: mdfi-pin1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755749 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0005811 name: atrip-ribc2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002009 ! ATRIP_HUMAN relationship: has_participant CCO:B0005240 ! RIBC2_HUMAN [Term] id: CCO:I0005812 name: appl1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002219 ! DP13A_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0005813 name: gorasp2-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:I0005814 name: c8orf32-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005179 ! CH032_HUMAN [Term] id: CCO:I0005815 name: il16-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755926 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0005242 ! Q8IUU6_HUMAN [Term] id: CCO:I0005816 name: lzts2-trim29 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:I0005817 name: psma1-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755941 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN [Term] id: CCO:I0005818 name: ard1-cdc25a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755974 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0005243 ! ARD1A_HUMAN [Term] id: CCO:I0005819 name: magea11-mlf1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755980 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001684 ! MLF1_HUMAN relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN [Term] id: CCO:I0005820 name: ccnk-cep76 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755986 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005244 ! CEP76_HUMAN [Term] id: CCO:I0005821 name: c10orf3-pom121 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001837 ! CEP55_HUMAN relationship: has_participant CCO:B0061984 ! P121A_HUMAN [Term] id: CCO:I0005822 name: lmo2-mapre3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002238 ! MARE3_HUMAN relationship: has_participant CCO:B0005171 ! RBTN2_HUMAN [Term] id: CCO:I0005823 name: nme1-polr1c physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756196 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0005246 ! RPAC1_HUMAN [Term] id: CCO:I0005824 name: chst1-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005247 ! CHST1_HUMAN [Term] id: CCO:I0005825 name: sept2-sept6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756268 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001775 ! SEPT6_HUMAN relationship: has_participant CCO:B0001800 ! SEPT2_HUMAN [Term] id: CCO:I0005826 name: rcn3-sufu physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756313 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005248 ! RCN3_HUMAN [Term] id: CCO:I0005827 name: mcm6-psma1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756361 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN [Term] id: CCO:I0005828 name: dlg7-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756439 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001807 ! DLGP5_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0005829 name: dlg7-trim37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756466 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001807 ! DLGP5_HUMAN relationship: has_participant CCO:B0005249 ! TRI37_HUMAN [Term] id: CCO:I0005830 name: actn4-myoz2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005250 ! MYOZ2_HUMAN [Term] id: CCO:I0005831 name: sssca1-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN [Term] id: CCO:I0005832 name: gorasp2-nme1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:I0005833 name: mcm6-scnm1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005251 ! SCNM1_HUMAN [Term] id: CCO:I0005834 name: mlh1-zc3h11a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0005252 ! ZC11A_HUMAN [Term] id: CCO:I0005835 name: myo15b-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756625 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005196 ! Q8N374_HUMAN [Term] id: CCO:I0005836 name: cct3-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756637 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0005253 ! TCPG_HUMAN [Term] id: CCO:I0005837 name: calm1-kiaa1683 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005254 ! K1683_HUMAN [Term] id: CCO:I0005838 name: krt18-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756694 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN [Term] id: CCO:I0005839 name: exoc8-krt18 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756712 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0005255 ! EXOC8_HUMAN [Term] id: CCO:I0005840 name: rbm7-rbmx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756715 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002255 ! RBM7_HUMAN relationship: has_participant CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:I0005841 name: fancg-samd3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0005257 ! SAMD3_HUMAN [Term] id: CCO:I0005842 name: ccnd3-dtnbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN [Term] id: CCO:I0005843 name: ccnd2-cdkn1a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001573 ! CCND2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0005844 name: c6orf55-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0005259 ! VTA1_HUMAN [Term] id: CCO:I0005845 name: ccnd3-efemp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN [Term] id: CCO:I0005846 name: mapre2-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0005847 name: sfn-tbl3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757024 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005261 ! Q96A78_HUMAN [Term] id: CCO:I0005848 name: cdc23-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757051 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:I0005849 name: c10orf119-ddit3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0005262 ! CJ119_HUMAN [Term] id: CCO:I0005850 name: mltk-znf567 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0005263 ! ZN567_HUMAN [Term] id: CCO:I0005851 name: phc1-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005264 ! PHC1_HUMAN [Term] id: CCO:I0005852 name: dyrk2-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005265 ! DYRK2_HUMAN [Term] id: CCO:I0005853 name: magea12-stat5a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0005266 ! MAGAC_HUMAN [Term] id: CCO:I0005854 name: frmd6-mlh1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0005267 ! FRMD6_HUMAN [Term] id: CCO:I0005855 name: dkfzp564e2182-tlk1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002220 ! TLK1_HUMAN relationship: has_participant CCO:B0005268 ! ASF1A_HUMAN [Term] id: CCO:I0005856 name: sufu-znf446 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN [Term] id: CCO:I0005857 name: chmp4b-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005270 ! CHM4B_HUMAN [Term] id: CCO:I0005858 name: mbip-mcm7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN [Term] id: CCO:I0005859 name: mapre2-mapre2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757483 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001811 ! MARE2_HUMAN [Term] id: CCO:I0005860 name: e2f6-tfdp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757528 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001429 ! E2F6_HUMAN relationship: has_participant CCO:B0001776 ! TFDP1_HUMAN [Term] id: CCO:I0005861 name: csnk1e-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005272 ! KC1E_HUMAN [Term] id: CCO:I0005862 name: dvl2-tp53 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757585 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN [Term] id: CCO:I0005863 name: sept1-tollip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN [Term] id: CCO:I0005864 name: lzts2-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757645 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0005865 name: khdrbs3-rbm7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757663 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002255 ! RBM7_HUMAN relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN [Term] id: CCO:I0005866 name: mgc13138-sufu physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005276 ! ZN764_HUMAN [Term] id: CCO:I0005867 name: cks2-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0005176 ! T22D4_HUMAN [Term] id: CCO:I0005868 name: dusp6-tex11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001824 ! DUS6_HUMAN relationship: has_participant CCO:B0005187 ! TEX11_HUMAN [Term] id: CCO:I0005869 name: mcrs1-med4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN [Term] id: CCO:I0005870 name: psmd2-ublcp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0005278 ! UBCP1_HUMAN [Term] id: CCO:I0005871 name: cdkn2d-tbc1d17 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0005279 ! TBC17_HUMAN [Term] id: CCO:I0005872 name: mcm5-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0005873 name: hgs-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0005874 name: hnrpc-pin1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:I0005875 name: rad54b-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0002260 ! RA54B_HUMAN [Term] id: CCO:I0005876 name: ube2i-zbed1x physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757915 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005231 ! ZBED1_HUMAN [Term] id: CCO:I0005877 name: mid1ip1-sufu physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757921 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005281 ! M1IP1_HUMAN [Term] id: CCO:I0005878 name: lzts2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758002 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0005879 name: mgc3162-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0005282 ! NOC4L_HUMAN [Term] id: CCO:I0005880 name: c10orf3-tsg101 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001837 ! CEP55_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0005881 name: pin1-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758248 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN [Term] id: CCO:I0005882 name: rad54b-ribc2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005240 ! RIBC2_HUMAN [Term] id: CCO:I0005883 name: ing5-mcm6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758263 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005284 ! ING5_HUMAN [Term] id: CCO:I0005884 name: ccnk-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0005885 name: c6orf55-cdk4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0005259 ! VTA1_HUMAN [Term] id: CCO:I0005886 name: hist2h3c-nasp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001626 ! NASP_HUMAN relationship: has_participant CCO:B0005285 ! H32_HUMAN [Term] id: CCO:I0005887 name: ccnd2-cdkn1b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758509 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001573 ! CCND2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0005888 name: c14orf48-c18orf24 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758521 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002032 ! SKA1_HUMAN relationship: has_participant CCO:B0005286 ! CN048_HUMAN [Term] id: CCO:I0005890 name: arih2-bub1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001395 ! BUB1_HUMAN relationship: has_participant CCO:B0005288 ! ARI2_HUMAN [Term] id: CCO:I0005891 name: pin1-rbbp8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758605 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005289 ! Q8NHQ3_HUMAN [Term] id: CCO:I0005892 name: mapre2-mapre3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0002238 ! MARE3_HUMAN [Term] id: CCO:I0005894 name: c1orf117-mad1l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005290 ! F131C_HUMAN [Term] id: CCO:I0005895 name: cct5-sssca1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0005291 ! TCPE_HUMAN [Term] id: CCO:I0005896 name: ddit3-spop physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0005292 ! SPOP_HUMAN [Term] id: CCO:I0005897 name: cdkn2b-magea11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN [Term] id: CCO:I0005898 name: cdkn1b-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0005899 name: kntc2-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0005210 ! USBP1_HUMAN [Term] id: CCO:I0005900 name: ccnk-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758917 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005293 ! KR412_HUMAN [Term] id: CCO:I0005901 name: trim29-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:I0005902 name: hgs-krt18 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0005903 name: krt18-nme7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0005294 ! NDK7_HUMAN [Term] id: CCO:I0005904 name: ccnk-pctk3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005295 ! PCTK3_HUMAN [Term] id: CCO:I0005905 name: mad1l1-trim29 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005204 ! TRI29_HUMAN [Term] id: CCO:I0005906 name: hmg20a-rbm7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002255 ! RBM7_HUMAN relationship: has_participant CCO:B0005296 ! HM20A_HUMAN [Term] id: CCO:I0005907 name: sufu-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005297 ! ZN263_HUMAN [Term] id: CCO:I0005908 name: prkar1a-pycard physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0005298 ! KAP0_HUMAN [Term] id: CCO:I0005909 name: fancg-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759091 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0005210 ! USBP1_HUMAN [Term] id: CCO:I0005910 name: ccnk-hmg20a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005296 ! HM20A_HUMAN [Term] id: CCO:I0005911 name: amotl2-kntc2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0005299 ! AMOL2_HUMAN [Term] id: CCO:I0005912 name: amotl2-mad1l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005299 ! AMOL2_HUMAN [Term] id: CCO:I0005913 name: rad54b-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN [Term] id: CCO:I0005914 name: gps2-tak1l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0005300 ! TAK1L_HUMAN [Term] id: CCO:I0005915 name: nono-pin1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005234 ! NONO_HUMAN [Term] id: CCO:I0005916 name: ccnd3-maf1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0005301 ! MAF1_HUMAN [Term] id: CCO:I0005917 name: cdca3-ctdsp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002076 ! CDCA3_HUMAN relationship: has_participant CCO:B0005302 ! CTDS1_HUMAN [Term] id: CCO:I0005918 name: mcm6-mllt3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005303 ! Q8IVB0_HUMAN [Term] id: CCO:I0005919 name: q8wu02-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005304 ! Q8WU02_HUMAN [Term] id: CCO:I0005920 name: hnrpc-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:I0005921 name: magea11-wtap physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759595 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001798 ! FL2D_HUMAN relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN [Term] id: CCO:I0005922 name: ewsr1-matk physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001612 ! MATK_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0005923 name: lnx-rad54b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0005305 ! LNX1_HUMAN [Term] id: CCO:I0005924 name: pbk-trim37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002045 ! TOPK_HUMAN relationship: has_participant CCO:B0005249 ! TRI37_HUMAN [Term] id: CCO:I0005925 name: actn4-myoz physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759703 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005306 ! MYOZ1_HUMAN [Term] id: CCO:I0005926 name: hhgp-stat5a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759712 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0032831 ! PRDC1_HUMAN [Term] id: CCO:I0005927 name: mad1l1-q9bvr6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759859 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005189 ! Q9BVR6_HUMAN [Term] id: CCO:I0005928 name: ube2i-znf451 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759886 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005308 ! ZN451_HUMAN [Term] id: CCO:I0005929 name: hnrpk-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:I0005931 name: mlh1-ubox5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0005309 ! RNF37_HUMAN [Term] id: CCO:I0005932 name: ewsr1-suv39h2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759964 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002139 ! SUV92_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0005933 name: tada3l-usp5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759979 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005310 ! UBP5_HUMAN [Term] id: CCO:I0005934 name: kiaa0514-sfn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005311 ! GRIN2_HUMAN [Term] id: CCO:I0005935 name: sept1-sept1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN [Term] id: CCO:I0005936 name: pex26-sufu physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005312 ! PEX26_HUMAN [Term] id: CCO:I0005937 name: krt15-mad2l1bp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0005207 ! K1C15_HUMAN [Term] id: CCO:I0005939 name: psmc1-psmd2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760192 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0005314 ! PRS4_HUMAN [Term] id: CCO:I0005940 name: pard6a-prkcz physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:I0005941 name: nme1-nme3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760207 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0005316 ! NDK3_HUMAN [Term] id: CCO:I0005942 name: cbx5-suv39h1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:I0005943 name: tada2l-tada3l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005318 ! Q9BVJ0_HUMAN [Term] id: CCO:I0005944 name: ccnd3-cdkn1b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760261 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0005945 name: khdrbs3-siah1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001946 ! SIAH1_HUMAN relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN [Term] id: CCO:I0005946 name: cdk4-cdkn2b-1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN [Term] id: CCO:I0005947 name: e2f6-tfdp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001429 ! E2F6_HUMAN relationship: has_participant CCO:B0001777 ! TFDP2_HUMAN [Term] id: CCO:I0005948 name: actn4-pdlim1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005319 ! PDLI1_HUMAN [Term] id: CCO:I0005949 name: mcm2-mcm6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:I0005950 name: fosl1-junb physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001522 ! FOSL1_HUMAN relationship: has_participant CCO:B0001530 ! JUNB_HUMAN [Term] id: CCO:I0005951 name: batf-ddit3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760366 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0005320 ! BATF_HUMAN [Term] id: CCO:I0005952 name: pias2-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005321 ! PIAS2_HUMAN [Term] id: CCO:I0005953 name: mad1l1-mad1l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN [Term] id: CCO:I0005954 name: smad4-ube2i physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760393 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN [Term] id: CCO:I0005955 name: nme1-nme1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760399 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001524 ! NDKA_HUMAN [Term] id: CCO:I0005956 name: ccnd3-cdkn1a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0005957 name: ccnd3-cdk4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN [Term] id: CCO:I0005958 name: mcm6-mcm6-1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:I0005959 name: fanca-fancg physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0005323 ! FANCA_HUMAN [Term] id: CCO:I0005960 name: mad1l1-mad2l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN [Term] id: CCO:I0005961 name: cebpg-ddit3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN [Term] id: CCO:I0005962 name: cdkn1a-pcna physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001513 ! PCNA_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0005963 name: pin2_trf1-eb1-1 physical interaction comment: Interaction between human Pin2/TRF1 and EB1 detected by coIP xref: IntAct:EBI-1004274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:I0005964 name: smc1-mcm7-1 physical interaction comment: Interaction between human Smc1 and MCM7 detected by TAP xref: IntAct:EBI-1004658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0005965 name: smc1-mcm7-3 physical interaction comment: Interaction between human Smc1 and MCM7 detected by coIP xref: IntAct:EBI-1004708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0005966 name: mcm7-smc1-2 physical interaction comment: Interaction between human MCM7 and Smc1 detected by coIP xref: IntAct:EBI-1004723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0005967 name: mcm6-smc1-1 physical interaction comment: Interaction between human MCM6 and Smc1 detected by coIP xref: IntAct:EBI-1004729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0005968 name: mcm6-mcm7-1 physical interaction comment: Interaction between human MCM6 and MCM7 detected by coIP xref: IntAct:EBI-1004735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:I0005969 name: il1b-il1r1-1 direct interaction comment: Type-1 interleukin-1 receptor complexed with interleukin-1 beta xref: IntAct:EBI-1026319 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN [Term] id: CCO:I0005970 name: hras-pik3cg-1 direct interaction comment: Ras g12v - pi 3-kinase gamma complex xref: IntAct:EBI-1030404 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005326 ! PK3CG_HUMAN [Term] id: CCO:I0005971 name: ctnnb1-tcf7l2-8 direct interaction comment: Crystal structure of a human tcf-4 / beta-catenin complex xref: IntAct:EBI-1032422 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0005972 name: egf-egfr-2 direct interaction comment: Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. xref: IntAct:EBI-1034411 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN [Term] id: CCO:I0005973 name: bmp7-nog-1 direct interaction comment: Crystal structure of bone morphogenetic protein-7 (bmp-7) in complex with the secreted antagonist noggin xref: IntAct:EBI-1035219 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001531 ! BMP7_HUMAN relationship: has_participant CCO:B0005328 ! NOGG_HUMAN [Term] id: CCO:I0005974 name: ube1c-ube2m-1 direct interaction comment: Structural basis for recruitment of ubc12 by an e2-binding domain in nedd8's e1 xref: IntAct:EBI-1041674 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001989 ! UBA3_HUMAN relationship: has_participant CCO:B0005329 ! UBC12_HUMAN [Term] id: CCO:I0005975 name: zo_1-actn4 physical interaction comment: ZO-1 interacting proteins xref: IntAct:EBI-1103214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005330 ! ZO1_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0005976 name: nedd8-tp53-1 neddylation comment: Neddylation of p53 xref: IntAct:EBI-1171060 is_a: CCO:Y0000036 ! neddylation reaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0001989 ! UBA3_HUMAN relationship: has_participant CCO:B0005329 ! UBC12_HUMAN relationship: has_participant CCO:B0005331 ! NEDD8_HUMAN relationship: has_participant CCO:B0005332 ! FBX11_HUMAN [Term] id: CCO:I0005977 name: hspb9-ctcf physical interaction comment: HSPB9 interacted with CTCF in a yeast two hybrid assay xref: IntAct:EBI-1176478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0005333 ! HSPB9_HUMAN [Term] id: CCO:I0005978 name: e6-e6ap-tp53 physical interaction xref: IntAct:EBI-1186940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005334 ! UBE3A_HUMAN [Term] id: CCO:I0005979 name: e6ap-tp53 physical interaction xref: IntAct:EBI-1186952 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005334 ! UBE3A_HUMAN [Term] id: CCO:I0005980 name: snip1-myc-2 physical interaction comment: SNIP1 coimmunoprecipitates c-Myc in HEK293 cell lysate xref: IntAct:EBI-1189163 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0005981 name: myc-snip1-1 physical interaction comment: SNIP1 coimmunoprecipitates with c-Myc in HEK293 cell lysate xref: IntAct:EBI-1189169 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0005982 name: max-myc-4 physical interaction comment: Max coimmunoprecipitates c-Myc in HEK293 cell lysate xref: IntAct:EBI-1189183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:I0005983 name: snip1-myc-4 physical interaction comment: SNIP1 coimmunoprecipitates c-Myc in HEK293 cell lysate xref: IntAct:EBI-1189347 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0005984 name: cdn1b-cdk2-1 physical interaction comment: Interaction between CDN1B (p27), Cyclin E1 and CDK2 identified by coimmunoprecipitation xref: IntAct:EBI-1201114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0005985 name: cdn1b-cdk2-2 physical interaction comment: Interaction between CDN1B (p27), Cyclin E1 and CDK2 identified by coimmunoprecipitation xref: IntAct:EBI-1201133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0005986 name: pcna-pold1-1 physical interaction comment: Interaction between PCNA, POLD1 and CHAF1A identified by coimmunoprecipitation xref: IntAct:EBI-1202904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001513 ! PCNA_HUMAN relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:I0005987 name: pcna-pold1-2 physical interaction comment: Interaction between PCNA, and CHAF1A identified by coimmunoprecipitation xref: IntAct:EBI-1202911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001513 ! PCNA_HUMAN relationship: has_participant CCO:B0001742 ! CAF1A_HUMAN [Term] id: CCO:I0005988 name: pard6a-prkci-1 physical interaction comment: Interacting regions determined by Y2H. xref: IntAct:EBI-295346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0005989 name: pard6a-prkcz-1 physical interaction comment: Interacting regions determined by Y2H. xref: IntAct:EBI-295374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:I0005990 name: pard6b-prkci-1 physical interaction comment: Interacting regions determined by Y2H. xref: IntAct:EBI-295401 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0005991 name: pard6b-prkcz-1 physical interaction comment: Interacting regions determined by Y2H. xref: IntAct:EBI-295414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:I0005992 name: pard6g-prkci-1 physical interaction comment: Interacting regions determined by Y2H. xref: IntAct:EBI-295426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002112 ! PAR6G_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0005993 name: pard6a-rac1-2 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-295457 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0005994 name: pard6a-cdc42-4 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-295464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0005995 name: pard6b-rac1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-295468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0005996 name: pard6b-cdc42-4 physical interaction comment: Interaction detected by Y2H : bait = cdc42, prey = par6b xref: IntAct:EBI-295472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0005997 name: pard6g-rac1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-295476 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002112 ! PAR6G_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0005998 name: pard6g-cdc42-1 physical interaction comment: Interaction detected by Y2H : bait = cdc42, prey = par6g xref: IntAct:EBI-295480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002112 ! PAR6G_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0005999 name: cdc37-cdk4 physical interaction comment: Interaction of cdc37 and CDK4 demonstrated by Y2H xref: IntAct:EBI-295633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001819 ! CDC37_HUMAN [Term] id: CCO:I0006000 name: daxx-crebbp-1 physical interaction comment: Interaction determined invivo by CoIP. xref: IntAct:EBI-296325 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0006001 name: crebbp-pax5-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-296342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005340 ! PAX5_HUMAN [Term] id: CCO:I0006002 name: rad51-brca2-1 physical interaction comment: Interaction of BRC4 repeat of BRCA2 with Rad51 determined by CoIP. xref: IntAct:EBI-297268 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0006003 name: hdac10-hdac3-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-297792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001376 ! HDAC3_HUMAN relationship: has_participant CCO:B0005341 ! HDA10_HUMAN [Term] id: CCO:I0006004 name: daxx-dek-1 physical interaction comment: Interaction in complex detected by CoIP. xref: IntAct:EBI-302174 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005221 ! H31_HUMAN relationship: has_participant CCO:B0005342 ! DEK_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005700 ! H4_HUMAN [Term] id: CCO:I0006005 name: daxx-hdac-1 physical interaction comment: Interaction of complex determined by CoIP. xref: IntAct:EBI-302180 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0006006 name: tubg-mark4-2 physical interaction comment: Association of MARK4 with gamma tubulin, detected by immunoprecipitation. xref: IntAct:EBI-351976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001548 ! TBG1_HUMAN relationship: has_participant CCO:B0005344 ! MARK4_HUMAN [Term] id: CCO:I0006007 name: tubg-mark4-3 physical interaction comment: Association of MARK4 with gamma tubulin, detected by immunoprecipitation. xref: IntAct:EBI-352004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001548 ! TBG1_HUMAN relationship: has_participant CCO:B0005344 ! MARK4_HUMAN [Term] id: CCO:I0006008 name: daxx-mcrs1-3 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-367115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006009 name: mcrs1-daxx-4 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-367120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006010 name: daxx-mcrs1-4 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-367126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006011 name: rassf1-xpa physical interaction comment: Interaction between RASSF1 and XPA identified by Y2H xref: IntAct:EBI-367371 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0005345 ! XPA_HUMAN [Term] id: CCO:I0006012 name: mphosph6-kiaa0052 physical interaction xref: IntAct:EBI-374346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005346 ! SK2L2_HUMAN [Term] id: CCO:I0006013 name: mphosph6-parn physical interaction xref: IntAct:EBI-374349 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005347 ! PARN_HUMAN [Term] id: CCO:I0006014 name: mphosph6-pmscl2 physical interaction xref: IntAct:EBI-374352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005348 ! EXOSX_HUMAN [Term] id: CCO:I0006015 name: lsm8-rent1 physical interaction xref: IntAct:EBI-374478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005349 ! LSM8_HUMAN [Term] id: CCO:I0006016 name: mdm2-mdm4-1 physical interaction comment: Yeast two-hybrid anlaysis identifies MDMX as an MDM2-binding protein. xref: IntAct:EBI-398450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0006017 name: e2f1-trrap-1 physical interaction comment: TRRAP and E2F1 interaction detected by coimmunoprecipitation xref: IntAct:EBI-448940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:I0006018 name: e2f4-trrap-1 physical interaction comment: TRRAP and E2F4 bind in vivo xref: IntAct:EBI-448954 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001817 ! E2F4_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:I0006019 name: htatip-trrap-1 physical interaction comment: Identification of subunits of human TIP60 histone acetylase complex. xref: IntAct:EBI-449133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:I0006020 name: orc1-cdk2-1 physical interaction comment: Interaction of hORC1 with Cyclin A/CDK2 xref: IntAct:EBI-492332 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0006021 name: orc1-orc2-1 physical interaction comment: Interaction of hORC1 with ORC2 xref: IntAct:EBI-492344 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0006022 name: nbs1-h2afx-2 physical interaction xref: IntAct:EBI-494971 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0006023 name: taf1-gtf2f1-3 physical interaction comment: Human TAFII-250 interacts with RAP74 xref: IntAct:EBI-515429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:I0006024 name: cul1-cand1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein and the TIP120A (CAND1) protein xref: IntAct:EBI-595237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006025 name: daxx-ar-1 physical interaction comment: Interaction of DAXX and AR detected by Y2H. xref: IntAct:EBI-608077 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:I0006026 name: daxx-ar-2 physical interaction comment: Interaction of DAXX and AR (sumoylation) detected by Y2H. xref: IntAct:EBI-608104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:I0006027 name: uhrf2-cdk2-1 physical interaction comment: Interaction between UHRF2 (NIRF) and CDK2 identified by coimmunoprecipitation xref: IntAct:EBI-625345 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0002054 ! UHRF2_HUMAN [Term] id: CCO:I0006028 name: uhrf2-cdk2-3 physical interaction comment: Interaction between UHRF2 (NIRF) and CDK2 identified by coimmunoprecipitation xref: IntAct:EBI-625371 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0002054 ! UHRF2_HUMAN [Term] id: CCO:I0006029 name: npm1-tp53-2 physical interaction comment: coIP: bait = npm1; prey =p53 xref: IntAct:EBI-626555 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:I0006030 name: hcfc1-many-4 physical interaction comment: interaction cosedimentation of Hcfc1, Sin3A, Ash2 and Sp1 in high-molecular-weight complexes xref: IntAct:EBI-630171 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN [Term] id: CCO:I0006031 name: sept1-aurkb-5 phosphorylation comment: Interaction of Septin1 and Aurora-B identified by GST pulldown xref: IntAct:EBI-693058 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:I0006032 name: wrn-rad52-9 colocalization comment: Colocalization of RAD52 and WRN xref: IntAct:EBI-706570 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006033 name: wrn-p53-3 colocalization comment: Colocalization of P53 and WRN in cells arrested in S phase xref: IntAct:EBI-708467 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006034 name: argef1-gbf1-6 colocalization comment: Colocalization of p115 and GBF1 in HeLa cells xref: IntAct:EBI-761833 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002023 ! ARHG1_HUMAN relationship: has_participant CCO:B0005359 ! GBF1_HUMAN [Term] id: CCO:I0006035 name: mrgbp-ruvbl1-1 physical interaction comment: MudPit analysis isolates proteins associated with MRGBP xref: IntAct:EBI-769767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005371 ! EPC2_HUMAN [Term] id: CCO:I0006036 name: tclf1-ruvbl1-2 physical interaction comment: MudPit analysis isolates proteins associated with TCLF1 xref: IntAct:EBI-769790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005367 ! ARP6_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005371 ! EPC2_HUMAN [Term] id: CCO:I0006037 name: znf-ruvbl1-3 physical interaction comment: MudPit analysis isolates proteins associated with ZNF xref: IntAct:EBI-769819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:I0006038 name: tclf1-ruvbl1-3 physical interaction comment: MudPit analysis of phosphocellulose chromatography fractions isolates proteins associated with TCLF1 xref: IntAct:EBI-769938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005367 ! ARP6_HUMAN [Term] id: CCO:I0006039 name: tclf1-ruvbl1-4 physical interaction comment: MudPit analysis of phosphocellulose chromatography fractions isolates proteins associated with TCLF1 xref: IntAct:EBI-777037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005367 ! ARP6_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005371 ! EPC2_HUMAN [Term] id: CCO:I0006040 name: tclf1-ruvbl1-5 physical interaction comment: MudPit analysis of phosphocellulose chromatography fractions isolates proteins associated with TCLF1 xref: IntAct:EBI-777062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005371 ! EPC2_HUMAN [Term] id: CCO:I0006041 name: tclf1-ruvbl1-6 physical interaction comment: MudPit analysis of phosphocellulose chromatography fractions isolates proteins associated with TCLF1 xref: IntAct:EBI-777086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN [Term] id: CCO:I0006042 name: tclf1-ruvbl1-7 physical interaction comment: MudPit analysis of phosphocellulose chromatography fractions isolates proteins associated with TCLF1 xref: IntAct:EBI-777108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005367 ! ARP6_HUMAN [Term] id: CCO:I0006043 name: adam9-mad2l2-3 physical interaction xref: IntAct:EBI-78229 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN [Term] id: CCO:I0006044 name: hd52-hd53-1 physical interaction comment: Interaction between human D52 and human D53 detected by Y2H xref: IntAct:EBI-782601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0005373 ! TPD52_HUMAN [Term] id: CCO:I0006045 name: hd53-hd52-1 physical interaction comment: Interaction between human D53 and human D52 detected by Y2H xref: IntAct:EBI-782630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0005373 ! TPD52_HUMAN [Term] id: CCO:I0006046 name: hd53-hd53-1 physical interaction comment: Homodimerisation of human D53 detected by Y2H xref: IntAct:EBI-782638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN [Term] id: CCO:I0006047 name: aplp2-apbb2-1 physical interaction comment: APLP2-FE65 co-ip xref: IntAct:EBI-79321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0005374 ! APLP2_HUMAN [Term] id: CCO:I0006048 name: stk36-sufu-1 physical interaction comment: Interaction between STK36 (FUSED) and SUFU identified by coimmunoprecipitation xref: IntAct:EBI-863810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005375 ! STK36_HUMAN [Term] id: CCO:I0006049 name: stk36-sufu-2 physical interaction comment: Interaction between STK36 (FUSED) and SUFU identified by coimmunoprecipitation xref: IntAct:EBI-863815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005375 ! STK36_HUMAN [Term] id: CCO:I0006050 name: ep300-nap1l1-3 direct interaction xref: IntAct:EBI-923621 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0006051 name: tcf4-ctnnb1-1 direct interaction comment: Coimmunoprecipitaion reveals interaction between Tcf4 and CTNNB1 xref: IntAct:EBI-924981 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0006052 name: pa2g4-rb1-1 physical interaction xref: IntAct:EBI-925146 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:I0006053 name: rb1-pa2g4-2 physical interaction xref: IntAct:EBI-925284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:I0006054 name: pa2g4-rb1-2 physical interaction xref: IntAct:EBI-925494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:I0006055 name: pa2g4-e2f1-1 physical interaction xref: IntAct:EBI-925581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:I0006056 name: ap2g-ubc9-1 physical interaction comment: Interaction between human AP2 gamma and UBC9 detected by Y2H xref: IntAct:EBI-937323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005377 ! AP2C_HUMAN [Term] id: CCO:I0006057 name: s100b-s100a6-1 physical interaction comment: Interaction between human S100B and S100A6 detected by Y2H xref: IntAct:EBI-945511 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0006058 name: cdknib-cdk4 physical interaction comment: Coimmunoprecipitaion reveals interaction between CDKN1B and CDK4 xref: IntAct:EBI-978118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0006059 name: cdknib-cdk2 physical interaction comment: Coimmunoprecipitaion reveals interaction between CDKN1B and CDK2 xref: IntAct:EBI-978130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0006060 name: daxx-stat3-1 physical interaction xref: IntAct:EBI-991352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:I0006061 name: daxx-stat3-2 physical interaction xref: IntAct:EBI-991377 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:I0006062 name: ahr-aip colocalization xref: IntAct:EBI-993202 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005380 ! AIP_HUMAN [Term] id: CCO:I0006063 name: ahr-aip-1 colocalization xref: IntAct:EBI-993238 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005380 ! AIP_HUMAN [Term] id: CCO:I0006064 name: kntc2-spbc25-1 physical interaction xref: IntAct:EBI-1000194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0006065 name: kntc2-spbc25-2 physical interaction xref: IntAct:EBI-1000254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0006066 name: kntc2_zwint_5 physical interaction comment: coIP: bait=kntc2, prey=zw10, zwint xref: IntAct:EBI-1001649 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006067 name: fgf1-fgfr2-1 direct interaction comment: Ligand-binding portion of fibroblast growth factor receptor 2 in complex with fgf1 xref: IntAct:EBI-1028822 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0005381 ! FGFR2_HUMAN [Term] id: CCO:I0006068 name: nfyb-nfyc-1 direct interaction comment: Crystal structure of the nf-yb-nf-yc histone pair xref: IntAct:EBI-1034602 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001770 ! NFYC_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN [Term] id: CCO:I0006069 name: hras-sos1-6 direct interaction comment: Crystal structure of a ternary ras:sos:ras*gdp complex xref: IntAct:EBI-1040575 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:I0006070 name: tp53-nfya-8 colocalization xref: IntAct:EBI-1040916 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006071 name: abl1-rin1-3 physical interaction comment: Interaction between Abl1 and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102773 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0006072 name: fnbp1-dnm2-2 physical interaction xref: IntAct:EBI-1111827 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:I0006073 name: ttn-tcap direct interaction xref: IntAct:EBI-1153057 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005387 ! TELT_HUMAN [Term] id: CCO:I0006074 name: mcm2-orc6l direct interaction xref: IntAct:EBI-375119 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0005388 ! ORC6_HUMAN [Term] id: CCO:I0006075 name: orc1l-hscdc6 direct interaction xref: IntAct:EBI-375122 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:I0006076 name: orc1l-hscdc5 direct interaction xref: IntAct:EBI-375125 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:I0006077 name: orc1l-mcm5 direct interaction xref: IntAct:EBI-375128 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:I0006078 name: mcm2-mcm3 direct interaction xref: IntAct:EBI-375131 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:I0006079 name: orc4l-mcm7 direct interaction xref: IntAct:EBI-375134 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN [Term] id: CCO:I0006080 name: mcm5-mcm3 direct interaction xref: IntAct:EBI-375137 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN [Term] id: CCO:I0006081 name: orc6l-mcm6 direct interaction xref: IntAct:EBI-375140 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005388 ! ORC6_HUMAN [Term] id: CCO:I0006082 name: mcm10-orc4l direct interaction xref: IntAct:EBI-375146 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001929 ! MCM10_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN [Term] id: CCO:I0006083 name: mcm10-mcm2 direct interaction xref: IntAct:EBI-375158 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006084 name: mcm2-orc2l direct interaction xref: IntAct:EBI-375161 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0006085 name: mcm10-mcm6 direct interaction xref: IntAct:EBI-375167 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006086 name: mcm2-mcm5 direct interaction xref: IntAct:EBI-375170 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:I0006087 name: mcm10-orc2l direct interaction xref: IntAct:EBI-375173 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001929 ! MCM10_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0006088 name: orc5l-cdc45l direct interaction xref: IntAct:EBI-375176 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001426 ! CC45L_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0006089 name: mcm2-cdk6 direct interaction xref: IntAct:EBI-375179 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0006090 name: orc6l-cdc7 direct interaction xref: IntAct:EBI-375188 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0005388 ! ORC6_HUMAN [Term] id: CCO:I0006091 name: orc4l-ccnd1 direct interaction xref: IntAct:EBI-375191 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN [Term] id: CCO:I0006092 name: mcm10-cdc7 direct interaction xref: IntAct:EBI-375197 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006093 name: mcm3-orc5l direct interaction xref: IntAct:EBI-375200 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0006094 name: mcm3-hscdc5 direct interaction xref: IntAct:EBI-375203 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:I0006095 name: mcm10-mcm3 direct interaction xref: IntAct:EBI-375206 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006096 name: orc4l-mcm3 direct interaction xref: IntAct:EBI-375209 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN [Term] id: CCO:I0006097 name: orc2l-hscdc5 direct interaction xref: IntAct:EBI-375212 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0006098 name: mcm10-ccnd3 direct interaction xref: IntAct:EBI-375215 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006099 name: mcm4-hscdc5 direct interaction xref: IntAct:EBI-375218 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:I0006100 name: orc2l-hscdc6 direct interaction xref: IntAct:EBI-375221 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0006101 name: mcm10-hscdc5 direct interaction xref: IntAct:EBI-375224 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001929 ! MCM10_HUMAN relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:I0006102 name: mcm2-ccnb2 direct interaction xref: IntAct:EBI-375227 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001446 ! CCNB2_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:I0006103 name: mcm6-mcm6 direct interaction xref: IntAct:EBI-375230 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:I0006104 name: mcm10-hscdc6 direct interaction xref: IntAct:EBI-375233 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001929 ! MCM10_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:I0006105 name: mcm10-ccnd1 direct interaction xref: IntAct:EBI-375236 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006106 name: mcm10-mcm7 direct interaction xref: IntAct:EBI-375242 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006107 name: orc3l-ccne2 direct interaction xref: IntAct:EBI-375245 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0006108 name: mcm2-mcm7 direct interaction xref: IntAct:EBI-375248 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:I0006109 name: mcm7-orc3l direct interaction xref: IntAct:EBI-375251 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0006110 name: mcm2-orc5l direct interaction xref: IntAct:EBI-375254 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0006111 name: mcm2-hscdc6 direct interaction xref: IntAct:EBI-375263 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:I0006112 name: cdk6-cdkn2a direct interaction xref: IntAct:EBI-375266 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0006113 name: cdk4-cdkn2a direct interaction xref: IntAct:EBI-375269 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN [Term] id: CCO:I0006114 name: mcm6-ccna1 direct interaction xref: IntAct:EBI-375272 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:I0006115 name: cdkn2a-gmnn direct interaction xref: IntAct:EBI-375275 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN [Term] id: CCO:I0006116 name: orc3l-mcm5 direct interaction xref: IntAct:EBI-375278 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0006117 name: orc4l-cdkn2a direct interaction xref: IntAct:EBI-375281 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN [Term] id: CCO:I0006118 name: orc5l-mcm5 direct interaction xref: IntAct:EBI-375287 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0006119 name: mcm10-cdk6 direct interaction xref: IntAct:EBI-375293 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006120 name: cdkn1a-ccnd3 direct interaction xref: IntAct:EBI-375296 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006121 name: mcm6-gmnn direct interaction xref: IntAct:EBI-375299 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:I0006122 name: hscdc6-orc5l direct interaction xref: IntAct:EBI-375302 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0006123 name: orc3l-hscdc6 direct interaction xref: IntAct:EBI-375305 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0006124 name: hscdc6-orc6l direct interaction xref: IntAct:EBI-375311 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0005388 ! ORC6_HUMAN [Term] id: CCO:I0006125 name: orc3l-mcm10 direct interaction xref: IntAct:EBI-375314 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001929 ! MCM10_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0006126 name: orc6l-mcm7 direct interaction xref: IntAct:EBI-375317 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005388 ! ORC6_HUMAN [Term] id: CCO:I0006127 name: cdk2-ccne2 direct interaction xref: IntAct:EBI-375320 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006128 name: cdkn2a-hscdc6 direct interaction xref: IntAct:EBI-375323 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:I0006129 name: cdk4-ccnd3 direct interaction comment: protein array : bait = cdk4, prey = cyclin D3 xref: IntAct:EBI-375326 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN [Term] id: CCO:I0006130 name: mcm2-cdk4 direct interaction xref: IntAct:EBI-375329 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:I0006131 name: cdk6-ccnd3 direct interaction xref: IntAct:EBI-375332 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0006132 name: cdkn1a-ccne2 direct interaction xref: IntAct:EBI-375335 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006133 name: cdkn2a-orc5l direct interaction xref: IntAct:EBI-375338 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0006134 name: cdk4-ccnd1 direct interaction comment: protein array : bait = cdk4, prey = cyclin D1 xref: IntAct:EBI-375341 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:I0006135 name: cdkn1a-cdc45l direct interaction xref: IntAct:EBI-375344 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001426 ! CC45L_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006136 name: cdkn1a-hscdc6 direct interaction xref: IntAct:EBI-375347 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:I0006137 name: cdkn1a-cdc7 direct interaction xref: IntAct:EBI-375350 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006138 name: cdc7-orc5l direct interaction xref: IntAct:EBI-375353 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0006139 name: cdkn2a-cdc45l direct interaction xref: IntAct:EBI-375356 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001426 ! CC45L_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN [Term] id: CCO:I0006140 name: cdkn1a-ccnd1 direct interaction xref: IntAct:EBI-375359 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006141 name: cdkn2a-cdc7 direct interaction xref: IntAct:EBI-375362 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN [Term] id: CCO:I0006142 name: mcm2-cdkn2a direct interaction xref: IntAct:EBI-375365 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN [Term] id: CCO:I0006143 name: cdk6-ccnd1 direct interaction xref: IntAct:EBI-375368 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0006144 name: mcm7-mcm5 direct interaction xref: IntAct:EBI-375371 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0001589 ! MCM7_HUMAN [Term] id: CCO:I0006145 name: cdkn2a-mcm10 direct interaction xref: IntAct:EBI-375374 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006146 name: mcm3-cdc7 direct interaction xref: IntAct:EBI-375380 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:I0006147 name: cdkn1a-hscdc5 direct interaction xref: IntAct:EBI-375383 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:I0006148 name: cdkn1a-cdk6 direct interaction xref: IntAct:EBI-375386 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0006149 name: cdkn1a-ccnb2 direct interaction xref: IntAct:EBI-375392 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001446 ! CCNB2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006150 name: orc2l-cdk2 direct interaction xref: IntAct:EBI-375395 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0006151 name: cdkn2a-mcm5 direct interaction xref: IntAct:EBI-375398 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN [Term] id: CCO:I0006152 name: cdkn1a-cdk4 direct interaction xref: IntAct:EBI-375404 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006153 name: mcm4-mcm7 direct interaction xref: IntAct:EBI-375407 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:I0006154 name: mcm3-hscdc6 direct interaction xref: IntAct:EBI-375410 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:I0006155 name: cdk2-ccnb2 direct interaction xref: IntAct:EBI-375413 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001446 ! CCNB2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006156 name: cdkn1a-ccna1 direct interaction xref: IntAct:EBI-375416 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN [Term] id: CCO:I0006157 name: mcm4-ccna1 direct interaction xref: IntAct:EBI-375419 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:I0006158 name: mcm3-cdk2 direct interaction xref: IntAct:EBI-375425 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001558 ! MCM3_HUMAN [Term] id: CCO:I0006159 name: cdkn1a-cdk2 direct interaction xref: IntAct:EBI-375428 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006160 name: cdkn1a-gmnn direct interaction xref: IntAct:EBI-375431 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006161 name: cdkn1a-mcm10 direct interaction xref: IntAct:EBI-375434 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN [Term] id: CCO:I0006162 name: cdc7-cdk4 direct interaction xref: IntAct:EBI-375437 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001512 ! CDK4_HUMAN [Term] id: CCO:I0006163 name: mcm3-mcm6 direct interaction xref: IntAct:EBI-375440 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN [Term] id: CCO:I0006164 name: nek1-fez1-2 physical interaction comment: Interaction between NEK1 and FEZ1 confirmed by GST pull down xref: IntAct:EBI-396654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN [Term] id: CCO:I0006165 name: nek1-fez2-1 physical interaction comment: Interaction between NEK1 and FEZ-2 confirmed by GST pull down xref: IntAct:EBI-396661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005394 ! FEZ2_HUMAN [Term] id: CCO:I0006166 name: bard1-htatip physical interaction xref: IntAct:EBI-474165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:I0006167 name: bard1-zhx1 physical interaction xref: IntAct:EBI-474172 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:I0006168 name: bard1-tcerg1-1 physical interaction xref: IntAct:EBI-474179 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN [Term] id: CCO:I0006169 name: bard1-git1-1 physical interaction xref: IntAct:EBI-474186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:I0006170 name: bard1-ikbkap physical interaction xref: IntAct:EBI-474193 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005398 ! ELP1_HUMAN [Term] id: CCO:I0006171 name: bard1-hbo1-1 physical interaction xref: IntAct:EBI-474200 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0006172 name: bard1-bp465 physical interaction xref: IntAct:EBI-474207 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005400 ! BRD7_HUMAN [Term] id: CCO:I0006173 name: bard1-kbtbd7 physical interaction xref: IntAct:EBI-474214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005401 ! KBTB7_HUMAN [Term] id: CCO:I0006174 name: bard1-pias4 physical interaction xref: IntAct:EBI-474221 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0006175 name: bard1-kiaa1377-1 physical interaction xref: IntAct:EBI-474235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0006176 name: bard1-setdb1 physical interaction comment: Y2H : BARD1 and SETDB1 xref: IntAct:EBI-474242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0006177 name: bard1-ptn physical interaction xref: IntAct:EBI-474256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0002086 ! BARD1_HUMAN [Term] id: CCO:I0006178 name: bard1-gprasp2 physical interaction xref: IntAct:EBI-474270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005405 ! GASP2_HUMAN [Term] id: CCO:I0006179 name: bard1-fez1 physical interaction xref: IntAct:EBI-474284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN [Term] id: CCO:I0006180 name: clk1-pias4 physical interaction xref: IntAct:EBI-474319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001632 ! CLK1_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0006181 name: tada3l-pias4-1 physical interaction xref: IntAct:EBI-474494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0006182 name: tada3l-mageh1 physical interaction xref: IntAct:EBI-474501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005406 ! MAGH1_HUMAN [Term] id: CCO:I0006183 name: hd-mtss1 physical interaction xref: IntAct:EBI-474739 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0006184 name: hd-mtss1-1 physical interaction xref: IntAct:EBI-474746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0006185 name: hd-mtss1-2 physical interaction xref: IntAct:EBI-474753 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0006186 name: ok/sw_cl_16-kpna2 physical interaction xref: IntAct:EBI-474984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0005408 ! Q8NI70_HUMAN [Term] id: CCO:I0006187 name: mageh1-kpna2 physical interaction xref: IntAct:EBI-474991 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0005406 ! MAGH1_HUMAN [Term] id: CCO:I0006188 name: kiaa1377-kpna2 physical interaction xref: IntAct:EBI-474998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0006189 name: kpnb1-ptn physical interaction xref: IntAct:EBI-475012 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN [Term] id: CCO:I0006190 name: tada3l-g22p1 physical interaction xref: IntAct:EBI-475019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0006191 name: gadd45g-ptn physical interaction xref: IntAct:EBI-475131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN [Term] id: CCO:I0006192 name: ptn-fez1 physical interaction xref: IntAct:EBI-475138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN [Term] id: CCO:I0006193 name: ptn-ptn physical interaction xref: IntAct:EBI-475145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN [Term] id: CCO:I0006194 name: pias4-ptn physical interaction comment: Y2H: PIASy and PTN xref: IntAct:EBI-475152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0006195 name: ptn-gprasp2 physical interaction xref: IntAct:EBI-475159 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005405 ! GASP2_HUMAN [Term] id: CCO:I0006196 name: rb1-taf1-1 physical interaction comment: Rb inhibits the intrinsic kinase acitivity of TAFII250, detected by GST pull-down. xref: IntAct:EBI-491318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001543 ! TAF1_HUMAN [Term] id: CCO:I0006197 name: orc1-skp2-2 physical interaction comment: Interaction of hORC1 with SKP2 xref: IntAct:EBI-492430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:I0006198 name: h2ax-tp53bp1-1 physical interaction xref: IntAct:EBI-495664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001526 ! H2AX_HUMAN relationship: has_participant CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:I0006199 name: taf1-gtf2f1-1 physical interaction comment: Human TAFII-250 interacts with RAP74. xref: IntAct:EBI-515106 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:I0006200 name: taf1-gtf2f1-2 physical interaction comment: Human TAFII-250 inteacts with RAP74 xref: IntAct:EBI-515162 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:I0006201 name: ccne1-nbs1-1 physical interaction xref: IntAct:EBI-520650 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN [Term] id: CCO:I0006202 name: ccne1-mre11a-1 physical interaction xref: IntAct:EBI-520656 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:I0006203 name: abl1-ywhaz-1 physical interaction comment: Interaction of ABL1 with 14-3-3 zeta protein demonstrated by coimmunoprecipitation xref: IntAct:EBI-593857 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0006204 name: abl1-snf-1 physical interaction comment: Interaction of ABL1 with 14-3-3 sigma protein demonstrated by coimmunoprecipitation xref: IntAct:EBI-593877 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN [Term] id: CCO:I0006205 name: smarca4-pb1-arid2-1 physical interaction comment: PBAF complex by chromatography analyzed by MS xref: IntAct:EBI-638253 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005419 ! SMRD2_HUMAN [Term] id: CCO:I0006206 name: sept1-aurkb-2 physical interaction comment: Interaction of Septin1 and Aurora-B identified by GST pulldown xref: IntAct:EBI-693019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:I0006207 name: bcl2-bax-2 physical interaction comment: Interaction of Bcl-2 with Bax demonstrated by coimmunoprecipitation xref: IntAct:EBI-700753 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN [Term] id: CCO:I0006208 name: bcl2-bak-1 physical interaction comment: Interaction of Bcl-2 with Bak demonstrated by coimmunoprecipitation xref: IntAct:EBI-700762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005420 ! BAK_HUMAN [Term] id: CCO:I0006209 name: bcl2-bad-1 physical interaction comment: Interaction of Bcl-2 with Bad demonstrated by coimmunoprecipitation xref: IntAct:EBI-700785 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:I0006210 name: bcl2-bik-1 physical interaction comment: Interaction of Bcl-2 with Bik demonstrated by coimmunoprecipitation xref: IntAct:EBI-700803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005421 ! BIK_HUMAN [Term] id: CCO:I0006211 name: bcl2-bid-1 physical interaction comment: Interaction of Bcl-2 with Bid demonstrated by coimmunoprecipitation xref: IntAct:EBI-700812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN [Term] id: CCO:I0006212 name: wrn-terf2-3 colocalization comment: Colocalization of WRM and TRF2 (TERF2) xref: IntAct:EBI-706680 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006213 name: dnmt3b-ube2i-2 physical interaction xref: IntAct:EBI-80234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN [Term] id: CCO:I0006214 name: rabgef1-egfr physical interaction xref: IntAct:EBI-921718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005424 ! EP15_HUMAN [Term] id: CCO:I0006215 name: atxn1-ccnk physical interaction xref: IntAct:EBI-946374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0006216 name: cenpj-gfi1b physical interaction xref: IntAct:EBI-946647 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005426 ! CENPJ_HUMAN [Term] id: CCO:I0006217 name: gfi1b-jag2 physical interaction xref: IntAct:EBI-946654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0002245 ! JAG2_HUMAN [Term] id: CCO:I0006218 name: gfi1b-nell2 physical interaction xref: IntAct:EBI-946661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005427 ! NELL2_HUMAN [Term] id: CCO:I0006219 name: s100b-s100a6-3 physical interaction comment: Interaction between human S100B and S100A6 detected by coIP xref: IntAct:EBI-959913 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0006220 name: csnk2a1-pml-1 phosphorylation xref: IntAct:EBI-983553 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0005428 ! CSK21_HUMAN [Term] id: CCO:I0006221 name: mdm2-daxx physical interaction xref: IntAct:EBI-992074 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006222 name: ubp7-daxx physical interaction xref: IntAct:EBI-992485 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0006223 name: pcaf-hif1a physical interaction xref: IntAct:EBI-996429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:I0006224 name: spbc24-spbc25-4 physical interaction xref: IntAct:EBI-1000026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0006225 name: cdca1_cenpb_1 colocalization xref: IntAct:EBI-1002609 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0005431 ! CENPB_HUMAN [Term] id: CCO:I0006226 name: kntc2_cenpb_1 colocalization xref: IntAct:EBI-1002612 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0005431 ! CENPB_HUMAN [Term] id: CCO:I0006227 name: smc1-mcm7-2 physical interaction comment: Interaction between human Smc1 and MCM7 detected by TAP xref: IntAct:EBI-1004670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0006228 name: rent1-dcp2 physical interaction xref: IntAct:EBI-1013186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:I0006229 name: dcp1a-upf1 physical interaction xref: IntAct:EBI-1013264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:I0006230 name: dcp2-upf physical interaction xref: IntAct:EBI-1013281 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:I0006231 name: upf1-dcp1a-2 physical interaction xref: IntAct:EBI-1013658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0005434 ! REN3B_HUMAN relationship: has_participant CCO:B0005435 ! RENT2_HUMAN relationship: has_participant CCO:B0005436 ! REN3A_HUMAN [Term] id: CCO:I0006232 name: bmp2-bmpr1a-1 direct interaction comment: Complex between bmp-2 and two bmp receptor ia ectodomains xref: IntAct:EBI-1029281 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0005437 ! BMR1A_HUMAN [Term] id: CCO:I0006233 name: fgf2-fgfr2-1 direct interaction comment: Crystal structure of ser252trp apert mutant fgf receptor 2 (fgfr2) in complex with fgf2 xref: IntAct:EBI-1031396 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0005381 ! FGFR2_HUMAN [Term] id: CCO:I0006234 name: fgf2-fgfr2-2 direct interaction comment: Crystal structure of pro253arg apert mutant fgf receptor 2 (fgfr2) in complex with fgf2 xref: IntAct:EBI-1031407 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0005381 ! FGFR2_HUMAN [Term] id: CCO:I0006235 name: ctnnb1-tcf7l2-7 direct interaction comment: Crystal structure of beta-catenin and htcf-4 xref: IntAct:EBI-1032405 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0006236 name: hgf-met-1 direct interaction comment: The crystal structure of hgf beta-chain in complex with the sema domain of the met receptor. xref: IntAct:EBI-1039192 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001518 ! HGF_HUMAN relationship: has_participant CCO:B0005438 ! MET_HUMAN [Term] id: CCO:I0006238 name: pard6a-prkci-3 direct interaction comment: Crystal structure of a pb1 domain complex of protein kinase c iota and par6 alpha xref: IntAct:EBI-1041315 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0006239 name: upf1-dcp1a-3 physical interaction xref: IntAct:EBI-1149045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0005434 ! REN3B_HUMAN relationship: has_participant CCO:B0005435 ! RENT2_HUMAN relationship: has_participant CCO:B0005436 ! REN3A_HUMAN [Term] id: CCO:I0006240 name: upf1-dcp1a-4 physical interaction xref: IntAct:EBI-1149055 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0005434 ! REN3B_HUMAN relationship: has_participant CCO:B0005436 ! REN3A_HUMAN [Term] id: CCO:I0006241 name: upf1-dcp1a-5 physical interaction xref: IntAct:EBI-1149083 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:I0006242 name: fbxo25-cul1-1 physical interaction comment: Interaction between FBXO25, CUL1 and SKP1A demonstrated by coimmunoprecipitation xref: IntAct:EBI-1161147 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005440 ! FBX25_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006243 name: fbxo4-cul1-2 physical interaction comment: Interaction between FBXO4, CUL1 and SKP1A demonstrated by coimmunoprecipitation xref: IntAct:EBI-1161214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005441 ! FBX4_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006244 name: fbxo7-cul1-1 physical interaction comment: Interaction between FBXO7, CUL1 and SKP1A demonstrated by coimmunoprecipitation xref: IntAct:EBI-1161237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005442 ! FBX7_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006245 name: dj_1-daxx-2 physical interaction xref: IntAct:EBI-1164461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005443 ! PARK7_HUMAN [Term] id: CCO:I0006246 name: tp53-fbxo11-3 physical interaction comment: Interaction between p53 and FBX011 identified by pulldown xref: IntAct:EBI-1168057 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005332 ! FBX11_HUMAN [Term] id: CCO:I0006247 name: ctcf-chd8-5 colocalization xref: IntAct:EBI-1169215 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:I0006248 name: nf1-sdc2 physical interaction comment: In a yeast two-hybrid assay neurofibromin binds syndecan-2 xref: IntAct:EBI-1172967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005445 ! SDC2_HUMAN [Term] id: CCO:I0006249 name: nf1-sdc2-1 physical interaction comment: In a yeast two-hybrid assay neurofibromin binds syndecan-2 xref: IntAct:EBI-1172987 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005445 ! SDC2_HUMAN [Term] id: CCO:I0006250 name: nf1-sdc2-3 physical interaction comment: In a yeast two-hybrid assay neurofibromin binds syndecan-2 xref: IntAct:EBI-1173237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005445 ! SDC2_HUMAN [Term] id: CCO:I0006251 name: nf1-sdc2-4 physical interaction comment: In a yeast two-hybrid assay neurofibromin binds syndecan-2 xref: IntAct:EBI-1173256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005445 ! SDC2_HUMAN [Term] id: CCO:I0006252 name: atm-aatf-1 phosphorylation comment: Che-1 is phosphorylated by ATM in vitro xref: IntAct:EBI-1180754 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0006253 name: atr-aatf-2 phosphorylation comment: Che-1 is phosphorylated by ATR in vitro xref: IntAct:EBI-1180766 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001756 ! ATR_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0006254 name: chek2-aatf-2 phosphorylation comment: Che-1 is phosphorylated by Chk2 in vitro xref: IntAct:EBI-1180914 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0006255 name: chek1-aatf phosphorylation comment: Che-1 is phosphorylated by Chk1 in vitro xref: IntAct:EBI-1180941 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0006256 name: atm-aatf-2 phosphorylation comment: Che-1 is phosphorylated by ATM in vitro xref: IntAct:EBI-1181015 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0006257 name: chek2-aatf-3 phosphorylation comment: Che-1 is phosphorylated by Chk2 in vitro xref: IntAct:EBI-1181029 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0006258 name: qsk-ywhaz-3 physical interaction comment: Interaction between 14-3-3Z , QSK and SNF1LK identified by pulldown xref: IntAct:EBI-1181833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0005229 ! MARK3_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:I0006259 name: nrp1-vegf physical interaction comment: Human VEGF165 interacted with human NRP1 in an ELISA assay xref: IntAct:EBI-1187131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0005447 ! NRP1_HUMAN [Term] id: CCO:I0006260 name: csnk1e-apc phosphorylation comment: CKI epsilon phosphorylates APC peptide in an in vitro phosphorylation assay xref: IntAct:EBI-1187596 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0005272 ! KC1E_HUMAN [Term] id: CCO:I0006261 name: egfr-calm-cav1 physical interaction xref: IntAct:EBI-1188138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005448 ! CLCA_HUMAN relationship: has_participant CCO:B0005449 ! TBA4A_HUMAN relationship: has_participant CCO:B0005450 ! ICAM1_HUMAN relationship: has_participant CCO:B0005451 ! HXC10_HUMAN relationship: has_participant CCO:B0005452 ! SEC13_HUMAN relationship: has_participant CCO:B0005453 ! AT1B1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005455 ! CD166_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0005459 ! AT1A1_HUMAN relationship: has_participant CCO:B0005460 ! CLH2_HUMAN relationship: has_participant CCO:B0005461 ! S10A9_HUMAN relationship: has_participant CCO:B0005462 ! CAV2_HUMAN relationship: has_participant CCO:B0005463 ! 4F2_HUMAN [Term] id: CCO:I0006262 name: src-cdn1b-1 phosphorylation comment: Phosphorylation of CDN1B by Src xref: IntAct:EBI-1200966 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:I0006263 name: yes-cdn1b-1 phosphorylation comment: Phosphorylation of CDN1B by Yes xref: IntAct:EBI-1201061 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005465 ! YES_HUMAN [Term] id: CCO:I0006264 name: tcf7l2-parp1-5 physical interaction comment: Ku70, Ku80, PARP1 and beta-catenin coimmunoprecipitate with FLAG-TCF-4 (TCF7L2) in HEK293 cell lysate xref: IntAct:EBI-1201435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0006265 name: lck-med28-2 physical interaction comment: Interaction between Lck and MED28 identified by coimmunoprecipitation xref: IntAct:EBI-1206888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN [Term] id: CCO:I0006266 name: cdc2l1-pak1-1 physical interaction comment: CDC2L1-PAK1 identified by Y2H xref: IntAct:EBI-1313 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:I0006267 name: cenpc1-daxx-1 colocalization comment: Colocalization detected by Fluorescence. xref: IntAct:EBI-295818 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:I0006268 name: brap-hras-2 physical interaction comment: Interaction between H-Ras and BRAP confirmed in vivo xref: IntAct:EBI-350178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:I0006269 name: daxx-ubl_1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-367065 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:I0006270 name: daxx-mcrs1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-367070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:I0006271 name: pml-ubl_1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-367073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:I0006272 name: daxx-mcrs1-2 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-367076 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006273 name: mcrs1-daxx-2 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-367083 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006274 name: mcrs1-daxx-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-367089 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006275 name: mcrs1-daxx-3 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-367097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006276 name: daxx-slc2a4-4 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-367179 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005473 ! GTR4_HUMAN [Term] id: CCO:I0006277 name: daxx-slc2a4-5 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-367184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005473 ! GTR4_HUMAN [Term] id: CCO:I0006278 name: egfr-grb2 physical interaction comment: in vitro interaction of egfr and grb2. xref: IntAct:EBI-370904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0006279 name: app-apbb1-2 physical interaction comment: app-fe65 in vivo interaction. xref: IntAct:EBI-371417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006280 name: q9nwa0-crsp6-1 physical interaction comment: Interaction detected by Anti FLAG CoIP followed by MudPIT. xref: IntAct:EBI-399874 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN [Term] id: CCO:I0006281 name: fancd2-brca2-2 physical interaction comment: Interaction between FACD2 and BRCA2 confirmed by co-immunoprecipitation xref: IntAct:EBI-446109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:I0006282 name: ywhaz-egfr-1 physical interaction comment: EGFR and 14-3-3 zeta interaction detected by filter binding xref: IntAct:EBI-446460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0006283 name: lck-lad-3 physical interaction comment: Lck- LAD confirmed by immunoprecipitation xref: IntAct:EBI-490666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005476 ! SH22A_HUMAN [Term] id: CCO:I0006284 name: trib3-atf5-1 physical interaction comment: Interaction detected by Y2H xref: IntAct:EBI-492520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN [Term] id: CCO:I0006285 name: igf1r-shc1-1 physical interaction comment: Interaction between IGF receptor1 and Shc1 demonstrated by Y2H xref: IntAct:EBI-517606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN [Term] id: CCO:I0006286 name: insr-shc1-1 physical interaction comment: Interaction between Insulin receptor1 and Shc1 demonstrated by Y2H xref: IntAct:EBI-517611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN [Term] id: CCO:I0006287 name: cam-cd95-1 physical interaction comment: The a region of the cytoplasmic domain of the CD95(Fas) protein (residues 230-270) interacts with the calmodulin protein xref: IntAct:EBI-518177 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN [Term] id: CCO:I0006288 name: cam-cd95pm physical interaction comment: Point mutations within the cytoplasmic domain of the CD95 protein reduce binding affinity for Calmodulin xref: IntAct:EBI-518367 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN [Term] id: CCO:I0006289 name: igf1r-ywhab-1 physical interaction comment: Interaction between IGF receptor1 and 14-3-3beta demonstrated by Y2H xref: IntAct:EBI-518483 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN [Term] id: CCO:I0006290 name: cdkn1a-ccne1-2 physical interaction comment: GST pull down : bait= cyclin E1, prey = p21-CIP1 xref: IntAct:EBI-519575 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006291 name: cdkn1b-ccne1-1 physical interaction comment: GST pull down : bait= cyclin E1, prey = p27-KIP xref: IntAct:EBI-519585 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0006292 name: cdkn1b-ccnb1-1 physical interaction comment: GST pull down : bait= cyclin B1 , prey = p27-KIP xref: IntAct:EBI-519593 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0006293 name: cdkn1a-ccne1-3 physical interaction comment: GST pull down : bait=p21-CIP1, prey = cyclin E1 xref: IntAct:EBI-519606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006294 name: cdkn1a-cdk2-1 physical interaction comment: GST pull down : bait= p21-CIP1, prey = cdk2 xref: IntAct:EBI-519614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006295 name: cdk2-ccne1-1 physical interaction comment: GST pull down : bait= cyclin E1, prey = cdk2 xref: IntAct:EBI-519628 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006296 name: bid-bcl2-1 physical interaction comment: interaction detected by CoIP xref: IntAct:EBI-519684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN [Term] id: CCO:I0006297 name: cdkn1a-ccne1-4 physical interaction comment: GST pull down : bait= cyclin E1, prey = p21-CIP1 xref: IntAct:EBI-519714 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006298 name: tbp-taf1-2 physical interaction comment: Interaction between TAFII-250 and TBP, detected by Y2H. xref: IntAct:EBI-520086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0005481 ! TBP_HUMAN [Term] id: CCO:I0006299 name: dapk-erk physical interaction comment: GST-pulldown reveals interaction between death-associated protein kinase 1protein and the mitogen-activated protein kinase 3 protein xref: IntAct:EBI-525573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0005482 ! DAPK1_HUMAN [Term] id: CCO:I0006300 name: dapk-erk-3 physical interaction comment: GST-pulldown reveals amino acid residues of the D domain of the death-associated protein kinase 1protein required for association with the mitogen-activated protein kinase 3 protein xref: IntAct:EBI-525646 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0005482 ! DAPK1_HUMAN [Term] id: CCO:I0006301 name: rent1-stau-2 physical interaction xref: IntAct:EBI-536599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005483 ! STAU1_HUMAN [Term] id: CCO:I0006302 name: hcfc1-hdac1-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and hdac1 xref: IntAct:EBI-540482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0006303 name: hcfc1-hdac2-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and hdac2 xref: IntAct:EBI-540490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0006304 name: hcfc1-sp1-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and sp1 xref: IntAct:EBI-540512 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005485 ! SP1_HUMAN [Term] id: CCO:I0006305 name: mll-hcfc2-2 physical interaction comment: MLL associates with a cohort of proteins, detected by coimmunoprecipitation. xref: IntAct:EBI-592993 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005486 ! HRX_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0036469 ! HCFC2_HUMAN relationship: has_participant CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:I0006306 name: srpk1-sfrs1-1 physical interaction comment: Interaction between SRPK1 and SFRS1 demonstrated by affinity chromatography xref: IntAct:EBI-593312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002061 ! SRPK1_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:I0006307 name: abl1-ywhab-1 physical interaction comment: Interaction of ABL1 with 14-3-3 proteins demonstrated by coimmunoprecipitation xref: IntAct:EBI-593829 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005489 ! 1433G_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0006308 name: cul1-cand1-4 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein and the TIP120A (CAND1) protein xref: IntAct:EBI-597772 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006309 name: cul1-cand1-5 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein and the TIP120A (CAND1) protein xref: IntAct:EBI-597861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006310 name: cul1-cand1-6 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein, TIP120A (CAND1) protein, RBX1 protein and SKP1 protein xref: IntAct:EBI-598059 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006311 name: numa1-gpsm2-1 physical interaction xref: IntAct:EBI-618688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0006312 name: numa1-gnai1-1 physical interaction xref: IntAct:EBI-618699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN [Term] id: CCO:I0006313 name: hcfc1-zbtb17-9 physical interaction comment: GST pull-down to identify which region(s) of zbtb17 (Miz1) are required for interaction with hcfc1. xref: IntAct:EBI-624221 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0006314 name: tacc1-lsm7-2 physical interaction comment: Identification of regions of TACC1 which binds to LSM7 by Y2H xref: IntAct:EBI-624677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0005494 ! LSM7_HUMAN [Term] id: CCO:I0006315 name: tacc1-snrpg-2 physical interaction comment: Regions of TACC1 which bind SNRPG1 (SmG) identified by Y2H xref: IntAct:EBI-624683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0005495 ! RUXG_HUMAN [Term] id: CCO:I0006316 name: tacc1-tdrd7-6 physical interaction comment: Identification of regions of TACC1 which interact with TDRD7 (TRAP) by Y2H xref: IntAct:EBI-624693 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0005496 ! TDRD7_HUMAN [Term] id: CCO:I0006317 name: tacc1-chtog-8 colocalization comment: TACC1, chTOG and STK6 (Aurora A) colocalise during metaphase xref: IntAct:EBI-624759 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001772 ! CKAP5_HUMAN [Term] id: CCO:I0006318 name: mdm2-npm1-4 physical interaction comment: coIP: bait = HDM2, prey = NPM xref: IntAct:EBI-626421 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0006319 name: npm1-tp53-3 physical interaction comment: coIP: bait = npm1; prey =p53 xref: IntAct:EBI-626567 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:I0006320 name: npm1-tp53-4 physical interaction comment: coIP: bait = npm1; prey =p53 xref: IntAct:EBI-626577 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN [Term] id: CCO:I0006321 name: nek2-nek11-8 phosphorylation comment: Autorepression of NEK2 xref: IntAct:EBI-633321 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001984 ! NEK11_HUMAN [Term] id: CCO:I0006322 name: pb1-arid2-4 physical interaction comment: coIP: bait = baf180; preys = baf200, brg1 xref: IntAct:EBI-637883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0006323 name: hcfc1-creb3-2 physical interaction comment: GST pull-down to show interaction between hcfc1 and creb3 and that the HBM is necessary for this interaction xref: IntAct:EBI-640484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN [Term] id: CCO:I0006324 name: pten-mast3-3 phosphorylation comment: Phosphorylation of human PTEN by Mast3 xref: IntAct:EBI-696526 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0005499 ! MAST3_HUMAN [Term] id: CCO:I0006325 name: rpa1-rpa2-1 direct interaction comment: Purification of Replication protein A complex (RPA70, RPA32, RPA14) xref: IntAct:EBI-707116 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005501 ! RFA3_HUMAN [Term] id: CCO:I0006326 name: blm-terf1-6 direct interaction comment: ELISA: bait= BLM, prey = TRF1 (TERF1) xref: IntAct:EBI-711022 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0006327 name: pot1-terf2 physical interaction comment: Coimmunoprecipitaion reveals interaction between POT1 ,TERF2 and TINF2 xref: IntAct:EBI-764923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005503 ! POTE1_HUMAN [Term] id: CCO:I0006328 name: acd-terf2 physical interaction comment: Coimmunoprecipitaion reveals interaction between ACD, POT1 ,TERF2 and TINF2 xref: IntAct:EBI-764927 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005503 ! POTE1_HUMAN relationship: has_participant CCO:B0005504 ! ACD_HUMAN [Term] id: CCO:I0006329 name: rap1-terf2-2 physical interaction comment: Coimmunoprecipitaion reveals interaction between RAP1, POT1 ,TERF2 and TINF2 xref: IntAct:EBI-764961 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005503 ! POTE1_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:I0006330 name: terf2-tinf2 physical interaction comment: Coimmunoprecipitaion reveals interaction between POT1 ,TERF2 and TINF2 xref: IntAct:EBI-764966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005503 ! POTE1_HUMAN [Term] id: CCO:I0006331 name: rap1-terf2-3 physical interaction comment: Coimmunoprecipitaion reveals interaction between RAP1,TERF2 and TINF2 xref: IntAct:EBI-765072 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:I0006332 name: ccna2_cdk2-1 direct interaction comment: Crystallisation of Cyclin A2 with CDK2 xref: IntAct:EBI-766822 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006333 name: tgfb1-bapp-1 physical interaction comment: Interaction between transforming growth factor beta 1 and beta amyloid precursor protein detected by crosslinking xref: IntAct:EBI-779649 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006334 name: tgfb2-bapp-5 physical interaction comment: Interaction between transforming growth factor beta and beta amyloid precursor protein detected by crosslinking xref: IntAct:EBI-779654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006335 name: sch1-app-3 physical interaction comment: APP-Shc A xref: IntAct:EBI-79022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006336 name: fshr-ywhaq-3 physical interaction comment: 14-3-3 tau interaction with FSHR is follitropin-dependent as shown by in vivo Co-IP xref: IntAct:EBI-848323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005506 ! FSHR_HUMAN [Term] id: CCO:I0006337 name: pola-pola2-6 physical interaction comment: Interaction between POLA, POLA2, PRI1 and PRI2 identified by antibody pulldown. xref: IntAct:EBI-850066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0005507 ! PRI1_HUMAN relationship: has_participant CCO:B0005508 ! PRI2_HUMAN relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:I0006338 name: pola-pri1-1 physical interaction comment: Interaction between POLA, PRI1 and PRI2 identified by antibody pulldown xref: IntAct:EBI-850113 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0005507 ! PRI1_HUMAN relationship: has_participant CCO:B0005508 ! PRI2_HUMAN [Term] id: CCO:I0006339 name: rar-mbd1 physical interaction comment: MBD1 interaction with RAR and HDAC detected using CoIP. xref: IntAct:EBI-867326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001376 ! HDAC3_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0006341 name: aml2-tle1-1 direct interaction comment: Interaction between human AML2 and TLE1 detected by far western xref: IntAct:EBI-926113 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0006342 name: bcl10-akt1-3 physical interaction comment: Interaction between BCL10 and Ak1 demonstrated by His-pulldown xref: IntAct:EBI-958953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:I0006343 name: bcl10-bcl3-3 physical interaction comment: Interaction between BCL3 and BCL10 demonstrated by His pulldown xref: IntAct:EBI-959037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN [Term] id: CCO:I0006344 name: tp53-lap-2 colocalization comment: Colocalisation assay reveals interaction between p53 protein and LAP (truncated CCAAT/enhancer-binding protein beta) protein xref: IntAct:EBI-970362 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN [Term] id: CCO:I0006345 name: pa2g4-npm-1 colocalization xref: IntAct:EBI-983124 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:I0006346 name: pa2g4-npm-2 colocalization xref: IntAct:EBI-983140 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:I0006347 name: ppp2r5d-sgol1-1 physical interaction xref: IntAct:EBI-989265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN [Term] id: CCO:I0006348 name: ppp2r5a-sgol2-2 physical interaction xref: IntAct:EBI-989272 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001840 ! SGOL2_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0006349 name: mdm2-daxx-1 physical interaction xref: IntAct:EBI-992237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006350 name: ubp7-daxx-2 colocalization xref: IntAct:EBI-992530 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0006351 name: ubp7-daxx-3 direct interaction xref: IntAct:EBI-992543 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0006352 name: pcaf-hif1a-1 physical interaction xref: IntAct:EBI-996456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:I0006353 name: sgol1-pp2r1b-ppp2r5a physical interaction xref: IntAct:EBI-999355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001840 ! SGOL2_HUMAN relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN relationship: has_participant CCO:B0005517 ! 2AAB_HUMAN relationship: has_participant CCO:B0005518 ! 2A5E_HUMAN relationship: has_participant CCO:B0005519 ! SET_HUMAN [Term] id: CCO:I0006354 name: map3k8-ruvbl1 physical interaction xref: IntAct:EBI-360717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005520 ! M3K8_HUMAN [Term] id: CCO:I0006355 name: nfkbia-mcm3 physical interaction xref: IntAct:EBI-360864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:I0006356 name: nfkbia-anxa1 physical interaction xref: IntAct:EBI-360909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001479 ! ANXA1_HUMAN relationship: has_participant CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:I0006357 name: ikbkb-q9bva1 physical interaction xref: IntAct:EBI-361272 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0006358 name: ikbke-kif11 physical interaction xref: IntAct:EBI-361305 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001659 ! KIF11_HUMAN relationship: has_participant CCO:B0005523 ! IKKE_HUMAN [Term] id: CCO:I0006359 name: ikbke-ruvbl1 physical interaction xref: IntAct:EBI-361326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005523 ! IKKE_HUMAN [Term] id: CCO:I0006360 name: ikbkg-smc2l1 physical interaction xref: IntAct:EBI-361431 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006361 name: ikbkg-msh2 physical interaction xref: IntAct:EBI-361485 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006362 name: ikbkg-mcm7 physical interaction xref: IntAct:EBI-361497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006363 name: ikbkg-dnch1 physical interaction xref: IntAct:EBI-361536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001780 ! DYHC1_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006364 name: ikbkg-smc4l1 physical interaction xref: IntAct:EBI-361614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002168 ! SMC4_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006365 name: ikbkg-q8ix12 physical interaction xref: IntAct:EBI-361650 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001950 ! CCAR1_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006366 name: ikbkg-ppp1cc physical interaction xref: IntAct:EBI-361656 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001596 ! PP1G_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006367 name: ikbkg-ppp1cb physical interaction xref: IntAct:EBI-361659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001689 ! PP1B_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006368 name: map3k1-q9bva1 physical interaction xref: IntAct:EBI-361917 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0006369 name: map3k1-nol1 physical interaction xref: IntAct:EBI-361980 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001623 ! NOL1_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0006370 name: map3k1-rps4x physical interaction xref: IntAct:EBI-361986 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001691 ! RS4X_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0006371 name: map3k1-cct4 physical interaction xref: IntAct:EBI-362019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001648 ! TCPD_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0006372 name: map3k3-pfdn1 physical interaction xref: IntAct:EBI-362049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006373 name: map3k3-hspa2 physical interaction xref: IntAct:EBI-362109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006374 name: map3k3-sugt1 physical interaction xref: IntAct:EBI-362124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002252 ! SUGT1_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006375 name: map3k3-mcc physical interaction xref: IntAct:EBI-362148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001549 ! CRCM_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006376 name: map3k3-actn4 physical interaction xref: IntAct:EBI-362163 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006377 name: map3k3-cct7 physical interaction xref: IntAct:EBI-362199 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002089 ! TCPH_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006378 name: map3k3-ruvbl1 physical interaction xref: IntAct:EBI-362211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006379 name: map3k3-ppp1ca physical interaction xref: IntAct:EBI-362262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001688 ! PP1A_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006380 name: map3k3-q9bva1 physical interaction xref: IntAct:EBI-362271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006381 name: map3k3-nudc physical interaction xref: IntAct:EBI-362289 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002250 ! NUDC_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006382 name: map3k3-ppp2r1a physical interaction xref: IntAct:EBI-362307 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006383 name: map3k3-tubb4 physical interaction xref: IntAct:EBI-362355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001754 ! TBB3_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006384 name: map3k3-cct2 physical interaction xref: IntAct:EBI-362382 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001700 ! TCPB_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006385 name: map3k3-ppp1cc physical interaction xref: IntAct:EBI-362412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001596 ! PP1G_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006386 name: map3k3-dlg1 physical interaction xref: IntAct:EBI-362427 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001736 ! DLG1_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006387 name: map3k3-cct4 physical interaction xref: IntAct:EBI-362460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001648 ! TCPD_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006388 name: nfkb2-rps4x physical interaction xref: IntAct:EBI-362863 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001691 ! RS4X_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0006389 name: map3k14-ruvbl1 physical interaction xref: IntAct:EBI-363022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0006390 name: map3k14-q9bva1 physical interaction xref: IntAct:EBI-363049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0006391 name: map3k14-rps4x physical interaction xref: IntAct:EBI-363112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001691 ! RS4X_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0006392 name: map3k14-rara physical interaction xref: IntAct:EBI-363184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0006393 name: relb-ruvbl1 physical interaction xref: IntAct:EBI-363502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0006394 name: ripk2-hspa2 physical interaction xref: IntAct:EBI-363658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN [Term] id: CCO:I0006395 name: ripk2-q9bva1 physical interaction xref: IntAct:EBI-363679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN [Term] id: CCO:I0006405 name: map3k7ip1-ruvbl1 physical interaction xref: IntAct:EBI-363988 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005531 ! TAB1_HUMAN [Term] id: CCO:I0006406 name: map3k7ip1-q9bva1 physical interaction xref: IntAct:EBI-363991 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005531 ! TAB1_HUMAN [Term] id: CCO:I0006407 name: q9nyj8-hspa2 physical interaction xref: IntAct:EBI-364039 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:I0006408 name: q9nyj8-ruvbl1 physical interaction xref: IntAct:EBI-364069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:I0006409 name: tbk1-cct7 physical interaction xref: IntAct:EBI-364243 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002089 ! TCPH_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0006410 name: tbk1-ruvbl1 physical interaction xref: IntAct:EBI-364246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0006411 name: tbk1-cct2 physical interaction xref: IntAct:EBI-364285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001700 ! TCPB_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0006412 name: tbk1-cct4 physical interaction xref: IntAct:EBI-364315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001648 ! TCPD_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0006413 name: tnfrsf1a-ruvbl1 physical interaction xref: IntAct:EBI-364402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0006414 name: tnfrsf1a-q9bva1 physical interaction xref: IntAct:EBI-364435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0006415 name: tnfrsf1b-mad2l1 physical interaction xref: IntAct:EBI-364597 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0006416 name: tnfrsf1b-q9bva1 physical interaction xref: IntAct:EBI-364687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0006417 name: traf2-ruvbl1 physical interaction xref: IntAct:EBI-365044 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0006418 name: traf2-frap1 physical interaction xref: IntAct:EBI-365062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001611 ! FRAP_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0006419 name: traf6-psmd8 physical interaction xref: IntAct:EBI-365128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001625 ! PSMD8_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0006420 name: traf6-psmd2 physical interaction xref: IntAct:EBI-365131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0006421 name: traf6-q9bva1 physical interaction xref: IntAct:EBI-365167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0006422 name: traf6-fancd2 physical interaction xref: IntAct:EBI-365182 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0006423 name: nfkbia-mcm5 physical interaction xref: IntAct:EBI-365271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:I0006424 name: nfkbia-mcm7 physical interaction xref: IntAct:EBI-365274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:I0006425 name: nfkbib-kpna2 physical interaction xref: IntAct:EBI-365310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0006426 name: nfkbib-mcc physical interaction xref: IntAct:EBI-365316 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001549 ! CRCM_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0006427 name: map3k14-cdc37 physical interaction xref: IntAct:EBI-365461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0006428 name: traf6-psmd1 physical interaction xref: IntAct:EBI-365491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002066 ! PSMD1_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0006429 name: nfkbie-ppp6c physical interaction xref: IntAct:EBI-365515 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001353 ! PPP6_HUMAN relationship: has_participant CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:I0006430 name: chuk-cdc37 physical interaction xref: IntAct:EBI-365524 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0006431 name: ikbkb-cdc37 physical interaction xref: IntAct:EBI-365539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0006432 name: ikbke-cdc37 physical interaction xref: IntAct:EBI-365551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005523 ! IKKE_HUMAN [Term] id: CCO:I0006433 name: ikbkg-cdc37 physical interaction xref: IntAct:EBI-365566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0006434 name: map3k1-cdc37 physical interaction xref: IntAct:EBI-365599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0006435 name: map3k3-ywhaq physical interaction xref: IntAct:EBI-365638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006436 name: map3k3-cdc37 physical interaction xref: IntAct:EBI-365644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0006437 name: relb-hdac6 physical interaction xref: IntAct:EBI-365713 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0006438 name: relb-kpna2 physical interaction xref: IntAct:EBI-365716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0006439 name: tbk1-cdc37 physical interaction xref: IntAct:EBI-365782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0006440 name: tnfrsf1a-fancd2 physical interaction xref: IntAct:EBI-365803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0006441 name: tnfrsf1a-tnf physical interaction xref: IntAct:EBI-365806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0006442 name: tnfrsf1b-fancd2 physical interaction xref: IntAct:EBI-365812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0006443 name: tnfrsf1b-tnf physical interaction xref: IntAct:EBI-365815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0006444 name: erbb2-egfr physical interaction xref: IntAct:EBI-1000539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0006445 name: erbb2-egfr-1 physical interaction xref: IntAct:EBI-1000674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0006446 name: kntc2_zwint_6 colocalization comment: colocalization of kntc2 and zwint xref: IntAct:EBI-1001660 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006447 name: zw10_zwint_2 colocalization comment: colocalization of zw10 and zwint xref: IntAct:EBI-1001663 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006448 name: zwint_mad2l1_1 colocalization comment: colocalization of zwint and mad2l1 xref: IntAct:EBI-1001666 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN [Term] id: CCO:I0006449 name: zwint_bub1b_1 colocalization comment: colocalization of zwint and bubr1 xref: IntAct:EBI-1001670 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006450 name: hras-sos1-1 direct interaction comment: Complex of human h-ras with human sos-1 xref: IntAct:EBI-1026981 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:I0006451 name: ccna2-cdk2-10 direct interaction comment: Structure of human thr160-phospho cdk2-cyclin a complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor xref: IntAct:EBI-1039432 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006452 name: ccna2-cdk2-11 direct interaction comment: Structure of human thr160-phospho cdk2-cyclin a complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor xref: IntAct:EBI-1039443 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006453 name: zo_1-actn4-1 physical interaction xref: IntAct:EBI-1103355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:I0006454 name: lkb1-strad-2 physical interaction comment: Interaction between STRAD and LKB1 determined by coimmunoprecipitation xref: IntAct:EBI-1109139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:I0006455 name: lkb1-strad-4 physical interaction comment: Interaction between STRAD and LKB1 determined by coimmunoprecipitation xref: IntAct:EBI-1109276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:I0006456 name: stk11-strad-5 physical interaction comment: Interaction between STRAD and STK11 (LKB1) determined by coimmunoprecipitation xref: IntAct:EBI-1109318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:I0006457 name: ahr-rb1 physical interaction xref: IntAct:EBI-1162624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001595 ! AHR_HUMAN [Term] id: CCO:I0006458 name: ahr-rb1-1 physical interaction xref: IntAct:EBI-1162695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001595 ! AHR_HUMAN [Term] id: CCO:I0006459 name: pin1-nek6-1 physical interaction comment: Interaction between PIN1 and NEK6 identified by GST-pulldown xref: IntAct:EBI-1164662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN [Term] id: CCO:I0006461 name: cops5-cdkn1b physical interaction comment: p27 coimmunoprecipitates with JAB1 in H1299 cell lysates xref: IntAct:EBI-1182075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0002025 ! CSN5_HUMAN [Term] id: CCO:I0006462 name: cdkn1b-uchl1 physical interaction comment: PGP9.5 coimmunoprecipitates with p27 in H1299 cell lysates xref: IntAct:EBI-1182097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005541 ! UCHL1_HUMAN [Term] id: CCO:I0006463 name: snip1-myc-1 physical interaction comment: SNIP1 coimmunoprecipitates c-Myc in HEK293 cell lysate xref: IntAct:EBI-1189138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0006464 name: tcf7l2-parp1 physical interaction comment: PARP1, Ku70 and Ku80 coimmunoprecipitate with FLAG-TCF-4 (TCF7L2) in HEK293 cell lysate xref: IntAct:EBI-1201106 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0006465 name: pard3-pard6a-1 physical interaction comment: Interaction between PAR3-PAR6 and PRKCi determined by CoIP. xref: IntAct:EBI-286228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN [Term] id: CCO:I0006466 name: pard6a-pard3-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-286235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN [Term] id: CCO:I0006467 name: prcki-pard6-1 physical interaction comment: Coimmunoprecipitation of PAR3 PAR6 and PRCKi . xref: IntAct:EBI-286254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0006468 name: daxx-tgfbr2-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-296166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005542 ! TGFR2_HUMAN [Term] id: CCO:I0006469 name: daxx-acvr2-1 physical interaction comment: Interaction determined by Y2H. xref: IntAct:EBI-296203 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN [Term] id: CCO:I0006470 name: daxx-daxx-1 physical interaction comment: Interaction determined by Y2H. xref: IntAct:EBI-296223 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006472 name: kiaa0578-kiaa0865 physical interaction xref: IntAct:EBI-311543 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002267 ! MYO16_HUMAN relationship: has_participant CCO:B0005545 ! NRX1A_HUMAN [Term] id: CCO:I0006473 name: celsr3-bpag1 physical interaction xref: IntAct:EBI-311579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001443 ! BPAEA_HUMAN relationship: has_participant CCO:B0005546 ! CELR3_HUMAN [Term] id: CCO:I0006474 name: kiaa1206-cul7 physical interaction xref: IntAct:EBI-311651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001795 ! CUL7_HUMAN relationship: has_participant CCO:B0005547 ! PLXB3_HUMAN [Term] id: CCO:I0006475 name: kiaa1206-parc physical interaction xref: IntAct:EBI-311667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001949 ! PARC_HUMAN relationship: has_participant CCO:B0005547 ! PLXB3_HUMAN [Term] id: CCO:I0006476 name: kiaa1549-bpag1 physical interaction xref: IntAct:EBI-311727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001443 ! BPAEA_HUMAN relationship: has_participant CCO:B0043861 ! K1549_HUMAN [Term] id: CCO:I0006478 name: rlg1-hras physical interaction comment: Interaction of HRas with RLG1 confirmed by GST pull-down xref: IntAct:EBI-366060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005550 ! RGL1_HUMAN [Term] id: CCO:I0006479 name: ahr-arnt-3 physical interaction comment: Interaction of AhR/ Arnt with ERAP 140 detected by CoIP. xref: IntAct:EBI-368115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:I0006480 name: ahr-arnt-4 physical interaction comment: Interaction of AhR/Arnt with Ncor2 detected by CoIP. xref: IntAct:EBI-368119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:I0006481 name: exosc4-nek1 physical interaction xref: IntAct:EBI-373659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005554 ! EXOS4_HUMAN [Term] id: CCO:I0006482 name: exosc5-cdk5rap1 physical interaction xref: IntAct:EBI-373707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002062 ! CK5P1_HUMAN relationship: has_participant CCO:B0005555 ! EXOS5_HUMAN [Term] id: CCO:I0006483 name: exosc8-ches1 physical interaction xref: IntAct:EBI-373722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001347 ! FOXN3_HUMAN relationship: has_participant CCO:B0005556 ! EXOS8_HUMAN [Term] id: CCO:I0006484 name: exosc3-cdk5rap1 physical interaction xref: IntAct:EBI-373737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002062 ! CK5P1_HUMAN relationship: has_participant CCO:B0005557 ! EXOS3_HUMAN [Term] id: CCO:I0006485 name: mphosph6-eif3s4 physical interaction xref: IntAct:EBI-373791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0026269 ! EIF3G_HUMAN [Term] id: CCO:I0006486 name: mphosph6-snx9 physical interaction xref: IntAct:EBI-373797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005559 ! SNX9_HUMAN [Term] id: CCO:I0006487 name: mphosph6-thop1 physical interaction xref: IntAct:EBI-373800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0035951 ! THOP1_HUMAN [Term] id: CCO:I0006488 name: mphosph6-q9y448 physical interaction xref: IntAct:EBI-373803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005561 ! T4AF1_HUMAN [Term] id: CCO:I0006489 name: mphosph6-dncl2a physical interaction xref: IntAct:EBI-373806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005562 ! DLRB1_HUMAN [Term] id: CCO:I0006490 name: mphosph6-rps20 physical interaction xref: IntAct:EBI-373809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005563 ! RS20_HUMAN [Term] id: CCO:I0006491 name: mphosph6-dnm2 physical interaction xref: IntAct:EBI-373815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0002071 ! MPH6_HUMAN [Term] id: CCO:I0006492 name: mphosph6-ded physical interaction xref: IntAct:EBI-373818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0006493 name: mphosph6-dkfzp762i16 physical interaction xref: IntAct:EBI-373821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005564 ! RHG18_HUMAN [Term] id: CCO:I0006494 name: skiv2l-cdc2l2 physical interaction xref: IntAct:EBI-373836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002241 ! CD2L2_HUMAN relationship: has_participant CCO:B0005565 ! SKIV2_HUMAN [Term] id: CCO:I0006495 name: lsm3-xpc physical interaction xref: IntAct:EBI-373914 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001714 ! XPC_HUMAN relationship: has_participant CCO:B0005566 ! LSM3_HUMAN [Term] id: CCO:I0006497 name: lsm8-ask/h37_(hudbf4 physical interaction xref: IntAct:EBI-374010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002194 ! DBF4A_HUMAN relationship: has_participant CCO:B0005349 ! LSM8_HUMAN [Term] id: CCO:I0006498 name: lsm8-sept5 physical interaction xref: IntAct:EBI-374022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0005349 ! LSM8_HUMAN [Term] id: CCO:I0006499 name: rent1-u315 physical interaction xref: IntAct:EBI-374151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005568 ! TR112_HUMAN [Term] id: CCO:I0006500 name: rent1-plekhb2 physical interaction xref: IntAct:EBI-374154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005569 ! PKHB2_HUMAN [Term] id: CCO:I0006501 name: rent1-acas2 physical interaction xref: IntAct:EBI-374160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005570 ! ACSA_HUMAN [Term] id: CCO:I0006502 name: rent1-bat5 physical interaction xref: IntAct:EBI-374163 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005571 ! BAT5_HUMAN [Term] id: CCO:I0006503 name: rent1-pepp2 physical interaction xref: IntAct:EBI-374166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0006504 name: rent1-c316g12_3 physical interaction xref: IntAct:EBI-374172 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005572 ! GNPTG_HUMAN [Term] id: CCO:I0006505 name: q9btt4-q71f56-1 physical interaction comment: Interaction detected by MudPIT xref: IntAct:EBI-394793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001553 ! CCNC_HUMAN relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0001950 ! CCAR1_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN relationship: has_participant CCO:B0005773 ! DDX3X_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005788 ! CD2L6_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005801 ! MD13L_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006100 ! RPB3_HUMAN relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0023090 ! TMLH_HUMAN relationship: has_participant CCO:B0030954 ! RPB4_HUMAN relationship: has_participant CCO:B0037269 ! PTBP1_HUMAN relationship: has_participant CCO:B0054324 ! ELL2_HUMAN relationship: has_participant CCO:B0055314 ! RPB9_HUMAN relationship: has_participant CCO:B0055511 ! RPAB4_HUMAN relationship: has_participant CCO:B0055606 ! RPAB2_HUMAN relationship: has_participant CCO:B0055622 ! RPAB5_HUMAN relationship: has_participant CCO:B0055987 ! RBM39_HUMAN relationship: has_participant CCO:B0059133 ! AFF4_HUMAN relationship: has_participant CCO:B0063138 ! RPAB3_HUMAN relationship: has_participant CCO:B0063162 ! TADBP_HUMAN relationship: has_participant CCO:B0063165 ! RPB11_HUMAN relationship: has_participant CCO:B0063166 ! RPB7_HUMAN relationship: has_participant CCO:B0063167 ! RPAB1_HUMAN relationship: has_participant CCO:B0063168 ! RPB2_HUMAN [Term] id: CCO:I0006506 name: q9nwa0-q71f56-1 physical interaction comment: Interaction detected by MudPIT xref: IntAct:EBI-394834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0001648 ! TCPD_HUMAN relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005788 ! CD2L6_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005801 ! MD13L_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006100 ! RPB3_HUMAN relationship: has_participant CCO:B0006110 ! SMN_HUMAN relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0023090 ! TMLH_HUMAN relationship: has_participant CCO:B0023192 ! SMD1_HUMAN relationship: has_participant CCO:B0030954 ! RPB4_HUMAN relationship: has_participant CCO:B0055348 ! LAP2A_HUMAN relationship: has_participant CCO:B0055606 ! RPAB2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN relationship: has_participant CCO:B0063165 ! RPB11_HUMAN relationship: has_participant CCO:B0063166 ! RPB7_HUMAN relationship: has_participant CCO:B0063167 ! RPAB1_HUMAN relationship: has_participant CCO:B0063168 ! RPB2_HUMAN relationship: has_participant CCO:B0063169 ! SR140_HUMAN relationship: has_participant CCO:B0063170 ! DCD_HUMAN relationship: has_participant CCO:B0063171 ! DDX52_HUMAN [Term] id: CCO:I0006507 name: q9nx70-q71f56-1 physical interaction comment: Interaction detected by MudPIT xref: IntAct:EBI-394875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001553 ! CCNC_HUMAN relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005568 ! TR112_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005773 ! DDX3X_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005788 ! CD2L6_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005801 ! MD13L_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN relationship: has_participant CCO:B0006100 ! RPB3_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN relationship: has_participant CCO:B0016149 ! PRP19_HUMAN relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0023090 ! TMLH_HUMAN relationship: has_participant CCO:B0023192 ! SMD1_HUMAN relationship: has_participant CCO:B0030954 ! RPB4_HUMAN relationship: has_participant CCO:B0037269 ! PTBP1_HUMAN relationship: has_participant CCO:B0050254 ! SFRS3_HUMAN relationship: has_participant CCO:B0055314 ! RPB9_HUMAN relationship: has_participant CCO:B0055348 ! LAP2A_HUMAN relationship: has_participant CCO:B0055606 ! RPAB2_HUMAN relationship: has_participant CCO:B0055622 ! RPAB5_HUMAN relationship: has_participant CCO:B0055987 ! RBM39_HUMAN relationship: has_participant CCO:B0058173 ! ZBTB9_HUMAN relationship: has_participant CCO:B0059141 ! DDX20_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN relationship: has_participant CCO:B0063049 ! EXOC4_HUMAN relationship: has_participant CCO:B0063138 ! RPAB3_HUMAN relationship: has_participant CCO:B0063162 ! TADBP_HUMAN relationship: has_participant CCO:B0063165 ! RPB11_HUMAN relationship: has_participant CCO:B0063166 ! RPB7_HUMAN relationship: has_participant CCO:B0063167 ! RPAB1_HUMAN relationship: has_participant CCO:B0063168 ! RPB2_HUMAN relationship: has_participant CCO:B0063169 ! SR140_HUMAN relationship: has_participant CCO:B0063171 ! DDX52_HUMAN relationship: has_participant CCO:B0063172 ! CC026_HUMAN relationship: has_participant CCO:B0063173 ! UC5IP_HUMAN relationship: has_participant CCO:B0063174 ! IDLC_HUMAN relationship: has_participant CCO:B0063175 ! DIMT1_HUMAN [Term] id: CCO:I0006508 name: crsp7-q71f56-1 physical interaction comment: Interaction detected by MudPIT xref: IntAct:EBI-394957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005788 ! CD2L6_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005801 ! MD13L_HUMAN relationship: has_participant CCO:B0006100 ! RPB3_HUMAN relationship: has_participant CCO:B0006110 ! SMN_HUMAN relationship: has_participant CCO:B0006151 ! PDIA1_HUMAN relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0030954 ! RPB4_HUMAN relationship: has_participant CCO:B0040253 ! IMA4_HUMAN relationship: has_participant CCO:B0054324 ! ELL2_HUMAN relationship: has_participant CCO:B0054719 ! UBR5_HUMAN relationship: has_participant CCO:B0055314 ! RPB9_HUMAN relationship: has_participant CCO:B0055348 ! LAP2A_HUMAN relationship: has_participant CCO:B0055606 ! RPAB2_HUMAN relationship: has_participant CCO:B0055622 ! RPAB5_HUMAN relationship: has_participant CCO:B0059133 ! AFF4_HUMAN relationship: has_participant CCO:B0063138 ! RPAB3_HUMAN relationship: has_participant CCO:B0063165 ! RPB11_HUMAN relationship: has_participant CCO:B0063166 ! RPB7_HUMAN relationship: has_participant CCO:B0063167 ! RPAB1_HUMAN relationship: has_participant CCO:B0063168 ! RPB2_HUMAN relationship: has_participant CCO:B0063170 ! DCD_HUMAN relationship: has_participant CCO:B0063176 ! DDX50_HUMAN [Term] id: CCO:I0006509 name: fance-fancd2-2 physical interaction comment: Interaction between FANCE and FANCD2 confirmed by his-tag pull down xref: IntAct:EBI-446090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0005576 ! FANCE_HUMAN [Term] id: CCO:I0006510 name: ruvbl1-ruvbl2-1 physical interaction comment: Interaction of RUVBL1 and RUVBL2 detected by gel filtration chromatography. xref: IntAct:EBI-449148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN [Term] id: CCO:I0006511 name: map3k5-sfn-1 physical interaction comment: Two hybrid interaction between human map kinase and 14-3-3 sigma xref: IntAct:EBI-476288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0006512 name: map3k5-ywhaq-1 physical interaction comment: Two hybrid interaction between human map kinase and 14-3-3 tau xref: IntAct:EBI-476319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0006513 name: sirt2-hdac6-2 colocalization comment: Interaction between SIRT2 and HDAC6 detected by colocalisation. xref: IntAct:EBI-489368 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN [Term] id: CCO:I0006514 name: h2afx-nbs1-1 physical interaction xref: IntAct:EBI-494856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0006515 name: nbs1-h2afx-1 physical interaction xref: IntAct:EBI-494873 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0006516 name: nbs1-mre11a-1 physical interaction xref: IntAct:EBI-494911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:I0006517 name: h2afx-mre11a-2 physical interaction xref: IntAct:EBI-494918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001526 ! H2AX_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:I0006518 name: h2afx-nbs1-2 physical interaction xref: IntAct:EBI-495007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0006519 name: daxx-tsg101 physical interaction comment: The death domain-associated protein 6 protein interacts with the tumor susceptibility gene 101 protein xref: IntAct:EBI-518492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0006520 name: dax-tsg101 physical interaction comment: The death domain-associated protein 6 protein ( residues 1 - 240) interacts with the tumor susceptibility gene 101 protein xref: IntAct:EBI-518751 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0006521 name: dax-tsg101-1 physical interaction comment: The death domain-associated protein 6 protein ( residues 241-492) interacts with the tumor susceptibility gene 101 protein xref: IntAct:EBI-518760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0006522 name: tsg101-daxx physical interaction comment: The tumor susceptibility gene 101 protein (residues 231-302) interacts with the death domain-associated protein 6 protein xref: IntAct:EBI-518769 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0006523 name: hcfc1-zbtb17-3 physical interaction comment: Y2H to identify the region(s) of hcfc1that is targeted by zbtb17 (Miz1) . xref: IntAct:EBI-621679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0006524 name: zbtb17-ep300 physical interaction comment: GST pull-down demonstrated that interaction between ep300 and zbtb17 is reduced by hcfc1, c-myc and zbtb17. xref: IntAct:EBI-624124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0006525 name: zn655-cdk4-2 physical interaction comment: Interaction between ZN655 (VIK) and CDK4 confirmed by coimmunoprecipitation xref: IntAct:EBI-625687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0005578 ! ZN655_HUMAN [Term] id: CCO:I0006526 name: zn655-cdk4-3 physical interaction comment: Interaction between ZN655 (VIK) and CDK4 confirmed by coimmunoprecipitation xref: IntAct:EBI-625742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0005578 ! ZN655_HUMAN [Term] id: CCO:I0006527 name: mdm2-npm1-2 physical interaction comment: GST pull down: bait = HDM2, prey = NPM xref: IntAct:EBI-626301 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0006528 name: mdm2-npm1-6 physical interaction comment: coIP: bait = HDM2; preys = NPM1 and p53 xref: IntAct:EBI-626521 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0006529 name: pias1-p53-1 direct interaction comment: GST pull-down: interaction between PIAS1 and P53 xref: IntAct:EBI-629447 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:I0006530 name: pias1-p53-2 direct interaction comment: GST pull-down: interaction between PIAS1 and P53 xref: IntAct:EBI-629452 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:I0006531 name: pias1-p53-3 direct interaction comment: GST pull-down: interaction between PIAS1 and P53 xref: IntAct:EBI-629459 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN [Term] id: CCO:I0006532 name: egf-egfr-1 direct interaction comment: Binding of EGF to the EGFR measured by a Scatchard plot xref: IntAct:EBI-640874 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN [Term] id: CCO:I0006533 name: sept1-aurkb-3 physical interaction comment: Interaction of Septin1 and Aurora-B identified by coimmunoprecipitation xref: IntAct:EBI-693031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:I0006534 name: wrn-terf2-1 physical interaction comment: Pull-down: bait= WRM, prey = TRF2 (TERF2) xref: IntAct:EBI-706633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006535 name: wrn-p53-1 direct interaction comment: Far-western : Probe = P53, prey = WRN xref: IntAct:EBI-708435 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006536 name: wrn-p53-2 direct interaction comment: Far-western : Probe = P53, prey = WRN xref: IntAct:EBI-708448 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006537 name: hspcb-aars physical interaction comment: In vivo Co-IP: bait= Hsp90 xref: IntAct:EBI-709762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001691 ! RS4X_HUMAN relationship: has_participant CCO:B0002066 ! PSMD1_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005746 ! RL7_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0005762 ! RLA0_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN relationship: has_participant CCO:B0015901 ! RS6_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0040243 ! PGK1_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0050859 ! C1TC_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN relationship: has_participant CCO:B0062802 ! FAS_HUMAN relationship: has_participant CCO:B0063029 ! KPYM_HUMAN relationship: has_participant CCO:B0063054 ! TPM3_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN relationship: has_participant CCO:B0063080 ! TCPA_HUMAN relationship: has_participant CCO:B0063092 ! HS105_HUMAN relationship: has_participant CCO:B0063177 ! UBA1_HUMAN relationship: has_participant CCO:B0063178 ! ALDOA_HUMAN relationship: has_participant CCO:B0063179 ! LDHA_HUMAN relationship: has_participant CCO:B0063180 ! SERC_HUMAN relationship: has_participant CCO:B0063181 ! MDHC_HUMAN relationship: has_participant CCO:B0063182 ! EF2_HUMAN relationship: has_participant CCO:B0063183 ! RL5_HUMAN relationship: has_participant CCO:B0063184 ! MYG1_HUMAN relationship: has_participant CCO:B0063185 ! SYAC_HUMAN relationship: has_participant CCO:B0063186 ! SIAS_HUMAN [Term] id: CCO:I0006538 name: blm-terf2-4 colocalization comment: Colocalization of BLM and TRF2 (TERF2) in Saos2 cells xref: IntAct:EBI-710878 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0006539 name: cdh1-ctnna1-1 physical interaction comment: Biosensor-Based Micro-Affinity Purification using GST epitope reveals interaction between CDH1 and protein fron Human SW480 cell line lysate xref: IntAct:EBI-762404 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005519 ! SET_HUMAN relationship: has_participant CCO:B0005581 ! CADH1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005824 ! CTNA1_HUMAN [Term] id: CCO:I0006540 name: apc-ctbb1-1 physical interaction comment: Biosensor-Based Micro-Affinity Purification using GST epitope reveals interaction between APC and CTBB1 proteins xref: IntAct:EBI-763296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005582 ! CAZA2_HUMAN relationship: has_participant CCO:B0005583 ! SC23A_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:I0006541 name: shc1-app-2 physical interaction comment: APP AID- Shc A xref: IntAct:EBI-78849 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006542 name: shc1-app-1 physical interaction comment: shcA PTB-APP Ccas xref: IntAct:EBI-78927 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006543 name: brca2-shfdg1-2 physical interaction comment: Interaction detected by mammalian two hybrid assay. xref: IntAct:EBI-79842 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0005586 ! DSS1_HUMAN [Term] id: CCO:I0006544 name: ahr-erap_140-1 physical interaction comment: Interaction detected by CoIP xref: IntAct:EBI-80806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:I0006545 name: ahr-arnt-1 physical interaction comment: Interaction of AhR/ Arnt with ERAP 140 detected by CoIP. xref: IntAct:EBI-80826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:I0006546 name: ahr-ncor2-1 physical interaction comment: Interaction detected by CoIP xref: IntAct:EBI-80844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:I0006547 name: ahr-arnt-2 physical interaction comment: Interaction of AhR/Arnt with Ncor2 detected by CoIP. xref: IntAct:EBI-80850 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:I0006548 name: top1-npm1 physical interaction comment: GST pull down assay reveals proteins interacting with the Topoisomerase 1 protein xref: IntAct:EBI-876315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001622 ! KI67_HUMAN relationship: has_participant CCO:B0001623 ! NOL1_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN relationship: has_participant CCO:B0005587 ! TOP1_HUMAN relationship: has_participant CCO:B0005725 ! ROA2_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0005774 ! ROA1_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005805 ! DDX21_HUMAN relationship: has_participant CCO:B0020752 ! PRP8_HUMAN relationship: has_participant CCO:B0020984 ! U520_HUMAN relationship: has_participant CCO:B0056099 ! ELAV1_HUMAN relationship: has_participant CCO:B0062841 ! DDX17_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN relationship: has_participant CCO:B0063122 ! U5S1_HUMAN relationship: has_participant CCO:B0063187 ! DDX23_HUMAN relationship: has_participant CCO:B0063188 ! H12_HUMAN relationship: has_participant CCO:B0063189 ! RU2A_HUMAN relationship: has_participant CCO:B0063190 ! H1X_HUMAN [Term] id: CCO:I0006549 name: top1-hnrpc physical interaction comment: GST pull down assay reveals proteins interacting with the Topoisomerase 1 protein xref: IntAct:EBI-876476 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN relationship: has_participant CCO:B0005587 ! TOP1_HUMAN relationship: has_participant CCO:B0005725 ! ROA2_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0005774 ! ROA1_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005805 ! DDX21_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0006275 ! HNRPL_HUMAN relationship: has_participant CCO:B0028239 ! ROA3_HUMAN relationship: has_participant CCO:B0038667 ! NAT10_HUMAN relationship: has_participant CCO:B0049991 ! SF3B1_HUMAN relationship: has_participant CCO:B0056099 ! ELAV1_HUMAN relationship: has_participant CCO:B0062841 ! DDX17_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN relationship: has_participant CCO:B0063188 ! H12_HUMAN relationship: has_participant CCO:B0063190 ! H1X_HUMAN [Term] id: CCO:I0006550 name: tcf4-daxx-2 colocalization comment: Colocalisation analysis reveals interaction between the TCF-4 protein and Daxx protein xref: IntAct:EBI-924854 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006551 name: aml2-tle1-2 physical interaction comment: Interaction between human AML2 and TLE1 detected by pulldown xref: IntAct:EBI-926176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0006552 name: cdk2-pin1-3 physical interaction comment: Interaction between Cdk2, cyclin E1 and Pin-1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-959207 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001755 ! PIN1_HUMAN [Term] id: CCO:I0006553 name: cdk2-ccne1-3 physical interaction comment: Interaction between Cdk2 and cyclin E1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-959219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006554 name: tp53-lip physical interaction comment: GST pull down assay reveals interaction between p53 protein and LIP (truncated CCAAT/enhancer-binding protein beta) protein xref: IntAct:EBI-969711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN [Term] id: CCO:I0006555 name: tp53-cebpb physical interaction comment: Coimmunoprecipitation assay reveals interaction between p53 protein and LIP (truncated CCAAT/enhancer-binding protein beta) protein xref: IntAct:EBI-969787 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN [Term] id: CCO:I0006556 name: mapk1-dusp1-1 physical interaction comment: Interaction between Erk2 and DUSP1 (MKP-1) demonstrated by pulldown xref: IntAct:EBI-975489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001566 ! DUS1_HUMAN [Term] id: CCO:I0006557 name: mapk1-dusp1-2 physical interaction comment: Interaction between Erk2 and DUSP1 (MKP-1) demonstrated by pulldown xref: IntAct:EBI-975528 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001566 ! DUS1_HUMAN [Term] id: CCO:I0006558 name: ppp2r5a-sgol1-1 physical interaction xref: IntAct:EBI-989343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0006559 name: ubp7-daxx-1 physical interaction xref: IntAct:EBI-992521 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0006560 name: ubp7-daxx-5 physical interaction xref: IntAct:EBI-992614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0006561 name: morf4l2-rb1-1 physical interaction xref: IntAct:EBI-995478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN [Term] id: CCO:I0006562 name: tp53-nfya-2 physical interaction xref: IntAct:EBI-1025813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006563 name: ccna2-cdk2-2 direct interaction comment: Phosphorylated cyclin-dependent kinase-2 bound to cyclin a xref: IntAct:EBI-1026138 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006564 name: tp53-nfya-3 physical interaction xref: IntAct:EBI-1028948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0006565 name: tp53-nfya-4 physical interaction xref: IntAct:EBI-1029255 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0006566 name: cdk2-cdkn3-1 direct interaction comment: Crystal structure of kinase associated phosphatase (kap) in complex with phospho-cdk2 xref: IntAct:EBI-1031555 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001823 ! CDKN3_HUMAN [Term] id: CCO:I0006567 name: tp53-nfya-7 physical interaction xref: IntAct:EBI-1040888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006568 name: cdc5l-akap9 physical interaction xref: IntAct:EBI-1105415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005588 ! AKAP9_HUMAN [Term] id: CCO:I0006569 name: cdc5l-aof2 physical interaction xref: IntAct:EBI-1105436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005589 ! LSD1_HUMAN [Term] id: CCO:I0006570 name: dtnbp1-ccna2 physical interaction xref: IntAct:EBI-1105504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN [Term] id: CCO:I0006572 name: disc1-cdc5l physical interaction xref: IntAct:EBI-1105515 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006573 name: disc1-cdc5l-1 physical interaction xref: IntAct:EBI-1105520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006574 name: exoc1-nuf2 physical interaction xref: IntAct:EBI-1105532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0005592 ! EXOC1_HUMAN [Term] id: CCO:I0006575 name: disc1-cdk5rap3-1 physical interaction xref: IntAct:EBI-1105543 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002044 ! CK5P3_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006576 name: disc1-cdk5rap3-2 physical interaction xref: IntAct:EBI-1105548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002044 ! CK5P3_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006577 name: cdc5l-crnkl1 physical interaction xref: IntAct:EBI-1105601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005593 ! CRNL1_HUMAN [Term] id: CCO:I0006578 name: cep63-cspg6 physical interaction xref: IntAct:EBI-1105611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005590 ! CEP63_HUMAN [Term] id: CCO:I0006579 name: disc1-dnch1 physical interaction xref: IntAct:EBI-1105668 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001780 ! DYHC1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006580 name: disc1-dnch1-2 physical interaction xref: IntAct:EBI-1105678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001780 ! DYHC1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006581 name: dtnbp1-bpag1 physical interaction xref: IntAct:EBI-1105748 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001884 ! Q5TBT1_HUMAN relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN [Term] id: CCO:I0006582 name: cdc5l-hook1 physical interaction xref: IntAct:EBI-1105837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005594 ! HOOK1_HUMAN [Term] id: CCO:I0006583 name: cdc5l-kiaa0182 physical interaction xref: IntAct:EBI-1105872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005595 ! GSE1_HUMAN [Term] id: CCO:I0006584 name: cdc5l-kiaa0240 physical interaction xref: IntAct:EBI-1105882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005596 ! K0240_HUMAN [Term] id: CCO:I0006585 name: cdc5l-znf451 physical interaction xref: IntAct:EBI-1105935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005597 ! Q5VVE9_HUMAN [Term] id: CCO:I0006586 name: cdc5l-kif3c physical interaction xref: IntAct:EBI-1105971 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005598 ! KIF3C_HUMAN [Term] id: CCO:I0006587 name: cdc5l-kif5b physical interaction xref: IntAct:EBI-1105991 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005599 ! KINH_HUMAN [Term] id: CCO:I0006588 name: cdc5l-kiaa1267 physical interaction xref: IntAct:EBI-1106006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005600 ! K1267_HUMAN [Term] id: CCO:I0006589 name: disc1-macf1 physical interaction xref: IntAct:EBI-1106028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006590 name: disc1-macf1-2 physical interaction xref: IntAct:EBI-1106038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006591 name: disc1-macf1-3 physical interaction xref: IntAct:EBI-1106043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006592 name: disc1-macf1-4 physical interaction xref: IntAct:EBI-1106049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006593 name: dtnbp1-macf1 physical interaction xref: IntAct:EBI-1106054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN [Term] id: CCO:I0006594 name: exoc1-macf1 physical interaction xref: IntAct:EBI-1106060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0005592 ! EXOC1_HUMAN [Term] id: CCO:I0006595 name: cdc5l-myt1l physical interaction xref: IntAct:EBI-1106107 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005601 ! MYT1L_HUMAN [Term] id: CCO:I0006596 name: disc1-pafah1b1 physical interaction xref: IntAct:EBI-1106185 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006597 name: disc1-pafah1b1-1 physical interaction xref: IntAct:EBI-1106190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006598 name: cdc5l-ppfia2 physical interaction xref: IntAct:EBI-1106216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005602 ! LIPA2_HUMAN [Term] id: CCO:I0006599 name: cdc5l-ppp1r13b physical interaction xref: IntAct:EBI-1106227 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002046 ! ASPP1_HUMAN relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN [Term] id: CCO:I0006600 name: tnik-ppp1r13b physical interaction xref: IntAct:EBI-1106232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002046 ! ASPP1_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:I0006601 name: disc1-rad21 physical interaction xref: IntAct:EBI-1106267 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006602 name: disc1-smc2l1 physical interaction xref: IntAct:EBI-1106323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006603 name: cdc5l-sptbn1 physical interaction xref: IntAct:EBI-1106395 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0006604 name: disc1-tubb2-1 physical interaction xref: IntAct:EBI-1106535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001769 ! TBB2A_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006605 name: cdc5l-ywhaz physical interaction xref: IntAct:EBI-1106576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0006606 name: cftr-ebp-1 physical interaction xref: IntAct:EBI-1171566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0005334 ! UBE3A_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005461 ! S10A9_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN relationship: has_participant CCO:B0016220 ! DNJB1_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN relationship: has_participant CCO:B0025069 ! NHRF2_HUMAN relationship: has_participant CCO:B0028758 ! SPTC1_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN relationship: has_participant CCO:B0051700 ! S10A7_HUMAN relationship: has_participant CCO:B0062989 ! LMNA_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN relationship: has_participant CCO:B0063206 ! HSP77_HUMAN relationship: has_participant CCO:B0063207 ! CYTB_HUMAN relationship: has_participant CCO:B0063208 ! SNX4_HUMAN relationship: has_participant CCO:B0063209 ! CALU_HUMAN relationship: has_participant CCO:B0063210 ! RCN1_HUMAN relationship: has_participant CCO:B0063211 ! SQRD_HUMAN [Term] id: CCO:I0006607 name: snip1-myc physical interaction comment: SNIP1 interacts with c-Myc in a yeast two-hybrid assay xref: IntAct:EBI-1188988 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0006608 name: cdk6-cdc37-1 physical interaction comment: Interaction between CDK6 and cdc37 confirmed in vitro xref: IntAct:EBI-295678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0001819 ! CDC37_HUMAN [Term] id: CCO:I0006609 name: cdk4-cdc37-1 physical interaction comment: Interaction between cdc37 and CDK4 confirmed in vitro xref: IntAct:EBI-295684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001819 ! CDC37_HUMAN [Term] id: CCO:I0006610 name: lats1-limk1-3 physical interaction comment: Interaction of human LATS1 and LIMK1 demonstrated by co-ip. xref: IntAct:EBI-444464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:I0006611 name: fancd2-fance-1 physical interaction comment: Direct interaction of FANCD2 with FANCE demonstrated by M2H xref: IntAct:EBI-446081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0005576 ! FANCE_HUMAN [Term] id: CCO:I0006612 name: p53-sin3a-2 physical interaction comment: Co-IP : bait = sin3a ; prey = P53 xref: IntAct:EBI-493242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:I0006613 name: cdc6-ubiq-1 physical interaction comment: Ubuiquitination of CDC6 demonstrated by coimmunoprecipitation xref: IntAct:EBI-514878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN [Term] id: CCO:I0006614 name: cdc2-myt1-1 phosphorylation comment: Phosphorylation of CDC2 by Myt1 xref: IntAct:EBI-515175 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0005607 ! MYT1_HUMAN [Term] id: CCO:I0006615 name: khdrbs1-ptpn6-1 physical interaction comment: Interaction between Sam68 and Shp-1 identified by coimmunoprecipitation xref: IntAct:EBI-518122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005608 ! PTN6_HUMAN [Term] id: CCO:I0006616 name: khdrbs1-fyn-1 physical interaction comment: Interaction between Sam68 and Fyn identified by coimmunoprecipitation xref: IntAct:EBI-518188 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0006617 name: khdrbs1-plcg1-1 physical interaction comment: Interaction between Sam68 and Phospholiase C gamma1 identified by coimmunoprecipitation xref: IntAct:EBI-518215 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005610 ! PLCG1_HUMAN [Term] id: CCO:I0006618 name: khdrbs1-grb2-1 physical interaction comment: Interaction between Sam68 and Grb2 identified by coimmunoprecipitation xref: IntAct:EBI-518222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0006619 name: khdrbs1-cbl-1 physical interaction comment: Interaction between Sam68 and Cbl identified by coimmunoprecipitation xref: IntAct:EBI-518240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:I0006620 name: khdrbs1-jak3-1 physical interaction comment: Interaction between Sam68 and JAK3 identified by coimmunoprecipitation xref: IntAct:EBI-518289 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005612 ! JAK3_HUMAN [Term] id: CCO:I0006621 name: khdrbs1-grb2-2 physical interaction comment: Interaction between Sam68 and Grb2 identified by coimmunoprecipitation xref: IntAct:EBI-518296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0006622 name: khdrbs1-jak3-2 physical interaction comment: Interaction between Sam68 and JAK3 identified by coimmunoprecipitation xref: IntAct:EBI-518302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005612 ! JAK3_HUMAN [Term] id: CCO:I0006623 name: khdrbs1-lck-1 physical interaction comment: Interaction between Sam68 and Lck identified by coimmunoprecipitation xref: IntAct:EBI-518312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:I0006624 name: hcfc1-set1-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and set1 xref: IntAct:EBI-540791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005613 ! SET1A_HUMAN [Term] id: CCO:I0006625 name: hcfc1-ash2l-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and ash2l xref: IntAct:EBI-540828 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN [Term] id: CCO:I0006626 name: hcfc1-wdr5-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and wdr5 xref: IntAct:EBI-540846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005615 ! WDR5_HUMAN [Term] id: CCO:I0006627 name: pparg-ep300 physical interaction comment: Interaction between PPAR-gamma and p300, detected by pull-down experiments. xref: IntAct:EBI-781445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005616 ! PPARG_HUMAN [Term] id: CCO:I0006628 name: adam9-mad2l2-2 physical interaction xref: IntAct:EBI-78173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN [Term] id: CCO:I0006629 name: sch1-app-2 physical interaction comment: shcA-APP in vivo xref: IntAct:EBI-78967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006630 name: dnmt3b-ubl1-ube2i-1 physical interaction xref: IntAct:EBI-80237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:I0006631 name: pard6a-tcp10-2 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-81885 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005617 ! TCP10_HUMAN [Term] id: CCO:I0006632 name: pard6a-cdc42-2 physical interaction comment: Interaction detected by Y2H : bait = par6da, prey = cdc42 xref: IntAct:EBI-81888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0006633 name: pard6a-tcp10-3 physical interaction comment: Deletion mutants of Par6c were analysed by Y2H for interaction with TC10. xref: IntAct:EBI-81902 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005617 ! TCP10_HUMAN [Term] id: CCO:I0006634 name: pard6a-cdc42-3 physical interaction comment: Deletion mutants of Par6C were analysed by Y2H for interaction with CDC42. xref: IntAct:EBI-81907 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0006635 name: thbd-f2-1 direct interaction comment: Kinetics of the interaction between thrombomodulin and thrombin measured by surface plasmon resonance xref: IntAct:EBI-941421 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0005618 ! TRBM_HUMAN [Term] id: CCO:I0006636 name: thbd-f2-2 direct interaction comment: Kinetics of the interaction between thrombomodulin and thrombin measured by surface plasmon resonance xref: IntAct:EBI-941543 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0005618 ! TRBM_HUMAN [Term] id: CCO:I0006637 name: thbd-f2-3 direct interaction comment: Kinetics of the interaction between thrombomodulin and thrombin measured by surface plasmon resonance xref: IntAct:EBI-941558 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0005618 ! TRBM_HUMAN [Term] id: CCO:I0006638 name: thbd-f2-4 direct interaction comment: Kinetics of the interaction between thrombomodulin and thrombin measured by surface plasmon resonance xref: IntAct:EBI-941573 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0005618 ! TRBM_HUMAN [Term] id: CCO:I0006640 name: hrasls3-ubqln4 physical interaction xref: IntAct:EBI-954950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001666 ! HRSL3_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0006641 name: mdk-ubqln4 physical interaction xref: IntAct:EBI-954998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001544 ! MK_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0006642 name: pin1-ubqln4 physical interaction xref: IntAct:EBI-955078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0006643 name: qscn6-ubqln4 physical interaction xref: IntAct:EBI-955118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001768 ! Q13876_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0006644 name: lzts2-a2bp1 physical interaction xref: IntAct:EBI-955310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0006645 name: ccnk-atxn1 physical interaction xref: IntAct:EBI-955430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0006646 name: cdk6-atxn1 physical interaction xref: IntAct:EBI-955438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0006647 name: pim2-atxn1 physical interaction xref: IntAct:EBI-955542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0006649 name: mad1l1-coil physical interaction xref: IntAct:EBI-955758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:I0006650 name: znrd1-gfi1b physical interaction xref: IntAct:EBI-955822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005622 ! RPA12_HUMAN [Term] id: CCO:I0006651 name: ewsr1-hbp1 physical interaction xref: IntAct:EBI-955830 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001407 ! HBP1_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0006652 name: ewsr1-hspa2 physical interaction xref: IntAct:EBI-955838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0006653 name: hspbp1-hspa2 physical interaction xref: IntAct:EBI-955846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005199 ! HPBP1_HUMAN [Term] id: CCO:I0006654 name: meox2-hspa2 physical interaction xref: IntAct:EBI-955854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005623 ! MEOX2_HUMAN [Term] id: CCO:I0006655 name: dvl2-tp53-1 physical interaction xref: IntAct:EBI-956102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN [Term] id: CCO:I0006656 name: mageb18-tp53-1 physical interaction xref: IntAct:EBI-956110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005185 ! MAGBI_HUMAN [Term] id: CCO:I0006657 name: scamp1-tp53 physical interaction xref: IntAct:EBI-956118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005624 ! SCAM1_HUMAN [Term] id: CCO:I0006658 name: gfi1b-cops5 physical interaction xref: IntAct:EBI-956654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0002025 ! CSN5_HUMAN [Term] id: CCO:I0006659 name: gfi1b-ccdc85b physical interaction xref: IntAct:EBI-956662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0043862 ! CC85B_HUMAN [Term] id: CCO:I0006660 name: gfi1b-begain-1 physical interaction xref: IntAct:EBI-956670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:I0006661 name: gfi1b-ushbp1 physical interaction xref: IntAct:EBI-956678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005210 ! USBP1_HUMAN [Term] id: CCO:I0006662 name: hbp1-kiaa1279 physical interaction xref: IntAct:EBI-956686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001407 ! HBP1_HUMAN relationship: has_participant CCO:B0043863 ! KBP_HUMAN [Term] id: CCO:I0006663 name: hspa2-hspbp1-1 physical interaction xref: IntAct:EBI-956702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005199 ! HPBP1_HUMAN [Term] id: CCO:I0006664 name: npm_alk-gak physical interaction xref: IntAct:EBI-968188 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001364 ! GAK_HUMAN relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001771 ! CD2L5_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005518 ! 2A5E_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN relationship: has_participant CCO:B0005610 ! PLCG1_HUMAN relationship: has_participant CCO:B0005612 ! JAK3_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0005976 ! PDLI5_HUMAN relationship: has_participant CCO:B0006034 ! JIP3_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0014968 ! EPHB3_HUMAN relationship: has_participant CCO:B0014973 ! EPHA1_HUMAN relationship: has_participant CCO:B0020951 ! MP2K7_HUMAN relationship: has_participant CCO:B0022073 ! SMC6_HUMAN relationship: has_participant CCO:B0022999 ! PTPRK_HUMAN relationship: has_participant CCO:B0023063 ! IF2M_HUMAN relationship: has_participant CCO:B0024487 ! PLCB2_HUMAN relationship: has_participant CCO:B0026602 ! P85B_HUMAN relationship: has_participant CCO:B0032342 ! K2C74_HUMAN relationship: has_participant CCO:B0036528 ! MYLK_HUMAN relationship: has_participant CCO:B0036805 ! PDX1_HUMAN relationship: has_participant CCO:B0037393 ! MARK1_HUMAN relationship: has_participant CCO:B0037928 ! IRF7_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN relationship: has_participant CCO:B0050510 ! IF4B_HUMAN relationship: has_participant CCO:B0051815 ! IRS4_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN relationship: has_participant CCO:B0055796 ! ITK_HUMAN relationship: has_participant CCO:B0055932 ! DGKZ_HUMAN relationship: has_participant CCO:B0055995 ! ITPR3_HUMAN relationship: has_participant CCO:B0056054 ! RAB35_HUMAN relationship: has_participant CCO:B0058496 ! RHG09_HUMAN relationship: has_participant CCO:B0063223 ! Q8N6V2_HUMAN relationship: has_participant CCO:B0063224 ! INSL6_HUMAN relationship: has_participant CCO:B0063225 ! LMNB1_HUMAN relationship: has_participant CCO:B0063226 ! FN3K_HUMAN relationship: has_participant CCO:B0063227 ! MEP1B_HUMAN [Term] id: CCO:I0006665 name: npm_alk-cdc14 physical interaction xref: IntAct:EBI-970278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0002092 ! CND3_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0018160 ! CC14B_HUMAN relationship: has_participant CCO:B0022232 ! PPID_HUMAN relationship: has_participant CCO:B0055505 ! NUP98_HUMAN relationship: has_participant CCO:B0058015 ! CSKI1_HUMAN [Term] id: CCO:I0006666 name: daxx-stat3 physical interaction xref: IntAct:EBI-991280 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:I0006667 name: cdc2l1-pak1-ac-vit physical interaction comment: CDC2L1-PAK1 identified by in vitro affinity chromatography xref: IntAct:EBI-1322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:I0006668 name: app-tp53bp2-2 physical interaction comment: APP-TP53BP2 xref: IntAct:EBI-77677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006669 name: apbb2-app-2 physical interaction comment: APP-FE65L co-ip xref: IntAct:EBI-79299 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006670 name: brca2-shfdg1-3 physical interaction comment: Interaction detected by coimmunoprecipitation. xref: IntAct:EBI-79847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0005586 ! DSS1_HUMAN [Term] id: CCO:I0006671 name: shfdg1-brca2-3 physical interaction comment: Interaction detected by coimmunoprecipitation. xref: IntAct:EBI-79852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0005586 ! DSS1_HUMAN [Term] id: CCO:I0006672 name: rps6ka4-mapk3 physical interaction comment: Interaction of Erk1 and Rsk-B identified by co-immunoprcipitation xref: IntAct:EBI-74011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0005629 ! KS6A4_HUMAN [Term] id: CCO:I0006673 name: hrmt1l1-rara-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78595 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0005630 ! ANM2_HUMAN [Term] id: CCO:I0006674 name: incenp-cbx5-1 physical interaction comment: Interaction of truncated INCENP and HP1detected by Y2H. xref: IntAct:EBI-307771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:I0006675 name: gp1ba-f2 physical interaction comment: Interaction between GP1BA and F2 detected by X-ray crystallography. xref: IntAct:EBI-297118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0005631 ! GP1BA_HUMAN [Term] id: CCO:I0006676 name: rad51-rad51-2 colocalization comment: Interaction detected by Fluroscence. xref: IntAct:EBI-297250 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0006677 name: grb2-egfr-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-297464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0001501 ! K2C7_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005221 ! H31_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN relationship: has_participant CCO:B0005819 ! CBLB_HUMAN relationship: has_participant CCO:B0005844 ! K1C17_HUMAN relationship: has_participant CCO:B0005875 ! CD59_HUMAN relationship: has_participant CCO:B0005900 ! K2C8_HUMAN relationship: has_participant CCO:B0015644 ! ACTH_HUMAN relationship: has_participant CCO:B0018244 ! SMD2_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN relationship: has_participant CCO:B0050497 ! PLEC1_HUMAN relationship: has_participant CCO:B0050501 ! EPIPL_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN relationship: has_participant CCO:B0055765 ! PTN11_HUMAN relationship: has_participant CCO:B0059207 ! VAV3_HUMAN relationship: has_participant CCO:B0062824 ! AP2M1_HUMAN relationship: has_participant CCO:B0063230 ! Q9Y6X7_HUMAN [Term] id: CCO:I0006678 name: hras-brap physical interaction comment: Interaction between H-Ras and BRAP1 in vivo xref: IntAct:EBI-350169 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:I0006679 name: myb-hipk2-1 physical interaction comment: Interaction of NLK, HIPK2 and MYB in vivo xref: IntAct:EBI-366992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002130 ! HIPK2_HUMAN relationship: has_participant CCO:B0005632 ! MYB_HUMAN [Term] id: CCO:I0006680 name: slc2a4-daxx-1 physical interaction comment: Invivo interaction detected by CoIP. xref: IntAct:EBI-367196 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005473 ! GTR4_HUMAN [Term] id: CCO:I0006681 name: daxx-slc2a4-6 physical interaction xref: IntAct:EBI-367199 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005473 ! GTR4_HUMAN [Term] id: CCO:I0006682 name: cul4b-tip120a-1 physical interaction comment: Interaction between CUL4B and TIP120A identified by co-affinity purification xref: IntAct:EBI-456087 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006683 name: cul4a-tip120a-1 physical interaction comment: Interaction between CUL4A and TIP120A identified by co-affinity purification xref: IntAct:EBI-456098 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006684 name: cul3-tip120a-2 physical interaction comment: Interaction between CUL3A and TIP120A identified by co-affinity purification xref: IntAct:EBI-456121 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001761 ! CUL3_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006685 name: cul1-tip120a-1 physical interaction comment: Interaction between CUL1 and TIP120A identified by co-affinity purification xref: IntAct:EBI-456160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006686 name: cul2-tip120a-2 physical interaction comment: Interaction between CUL2 and TIP120A identified by co-affinity purification xref: IntAct:EBI-456171 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001760 ! CUL2_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006687 name: cul4b-tip120a-2 physical interaction comment: Interaction between CUL4B and TIP120A identified by co-affinity purification xref: IntAct:EBI-456195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006688 name: cul1-tip120a-2 physical interaction comment: Interaction between CUL1 and TIP120A identified by coimmunoprecipitation xref: IntAct:EBI-456207 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006689 name: cul2-tip120a-1 physical interaction comment: Interaction between CUL2 and TIP120A identified by co-immunoprecipitation xref: IntAct:EBI-456217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001760 ! CUL2_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006690 name: cul3-tip120a-1 physical interaction comment: Interaction between CUL3 and TIP120A identified by coimmunoprecipitation xref: IntAct:EBI-456227 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001761 ! CUL3_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006691 name: cul4a-tip120a-2 physical interaction comment: Interaction between CUL4A and TIP120A identified by coimmunoprecipitation xref: IntAct:EBI-456237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006692 name: cul4b-tip120a-3 physical interaction comment: Interaction between CUL4B and TIP120A identified by coimmunprecipitation xref: IntAct:EBI-456247 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0006693 name: cul1-tip120a-3 physical interaction comment: Formation of Skp1/F-box protein complex xref: IntAct:EBI-456255 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006694 name: cul1-tip120a-4 physical interaction comment: Formation of ubiquitin ligase protein complex xref: IntAct:EBI-456271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006695 name: cul1-skp1-1 physical interaction comment: Formation of skp1/f-box protein complex xref: IntAct:EBI-456324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006696 name: cul1-skp1-2 physical interaction comment: Formation of skp1/f-box protein complex xref: IntAct:EBI-456337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006697 name: cul1-skp1-3 physical interaction comment: Interaction between CUL1 and SKP1 demonstrated by co-immunoprecipitation xref: IntAct:EBI-456350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006698 name: tp53-tbp1 physical interaction comment: Interaction between the C-terminal end of p53 and TBP detected by Western blotting. xref: IntAct:EBI-398460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005481 ! TBP_HUMAN [Term] id: CCO:I0006699 name: tp53-tbp-2 physical interaction comment: Interaction between p53 and TBP detected by Western blot. xref: IntAct:EBI-398465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005481 ! TBP_HUMAN [Term] id: CCO:I0006700 name: cdk8-q9btt4 physical interaction comment: Interaction detected by anti-FLAG coimmunoprecipitation. xref: IntAct:EBI-394387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:I0006701 name: crsp7-cdk8-1 physical interaction comment: Interaction detected by anti-FLAG CoIP. xref: IntAct:EBI-394419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0021690 ! RPB1_HUMAN [Term] id: CCO:I0006702 name: hif1a-ep300-3 physical interaction comment: Interaction of HIF1A with EP300 confirmed by CoIP. xref: IntAct:EBI-447509 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:I0006703 name: trrap-myc-2 physical interaction comment: Interaction of TRRAP requires N-terminal domains in c-Myc. xref: IntAct:EBI-447565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:I0006704 name: akip-stk6-1 physical interaction comment: immunoprecipitation, bait = human AKIP, prey = human Aurora A xref: IntAct:EBI-448670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0002171 ! AKIP_HUMAN [Term] id: CCO:I0006705 name: plk1-mcm7-3 physical interaction comment: Interaction between PLK1 and MINC7 detected by pull down using purified GST-PLK1 and endogenous MNC7 present in HEK-293T cells lysate xref: IntAct:EBI-476833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:I0006706 name: gna13-arhgef1-1 physical interaction comment: Co-IP bait=human P115, prey = human G alpha 13 xref: IntAct:EBI-465428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002023 ! ARHG1_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN [Term] id: CCO:I0006707 name: gna13-arhgef1-2 physical interaction comment: Co-IP bait= human G alpha 13, prey = human P115 xref: IntAct:EBI-465471 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002023 ! ARHG1_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN [Term] id: CCO:I0006708 name: sirt2-hdac6-1 physical interaction comment: Interaction between SIRT2 and HDAC6 detected by CoIP. xref: IntAct:EBI-489322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN [Term] id: CCO:I0006709 name: raf1-hras-2 physical interaction comment: Y2H: bait = C-Raf ,prey = HA-Ras-C-Ha-ras p21 protein xref: IntAct:EBI-537342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0006710 name: ask1-daxx physical interaction comment: The mitogen-activated protein kinase kinase kinase 5 protein interacts with the death domain-associated protein 6 protein xref: IntAct:EBI-519022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0006711 name: ask1-daxx-1 physical interaction comment: The N terminal region of the mitogen-activated protein kinase kinase kinase 5 protein interacts with the death domain-associated protein 6 protein xref: IntAct:EBI-519032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0006712 name: khdrbs1-lyn-1 physical interaction comment: Interaction between Sam68 and Lyn identified by coimmunoprecipitation xref: IntAct:EBI-518323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:I0006713 name: crebbp-khdrbs1-9 colocalization comment: Interaction of CBP with Sam68 demonstrated by GST pull-down xref: IntAct:EBI-519704 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0006714 name: tbp-taf1-1 physical interaction comment: TAFII-250 binds to TBP, as detected by far-western. xref: IntAct:EBI-520065 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0005481 ! TBP_HUMAN [Term] id: CCO:I0006715 name: rent1-stau-3 physical interaction xref: IntAct:EBI-536608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005483 ! STAU1_HUMAN [Term] id: CCO:I0006716 name: rent1-stau-4 physical interaction xref: IntAct:EBI-536615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005483 ! STAU1_HUMAN [Term] id: CCO:I0006717 name: mapk3-elk1-1 phosphorylation comment: Phosphorylation of ELK1 by MAPK3 (Erk1) xref: IntAct:EBI-959845 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0005637 ! ELK1_HUMAN [Term] id: CCO:I0006718 name: mapk1-elk1-1 phosphorylation comment: Phosphorylation of ELK1 by MAPK31(Erk2) xref: IntAct:EBI-959983 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0005637 ! ELK1_HUMAN [Term] id: CCO:I0006719 name: mapk8-jun-1 phosphorylation comment: Phosphorylation of c-jun by MAPK8 (JNK1) xref: IntAct:EBI-960011 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001487 ! JUN_HUMAN relationship: has_participant CCO:B0005638 ! MK08_HUMAN [Term] id: CCO:I0006720 name: msh2-msh6-1 physical interaction comment: Interaction between human MSH2 and MSH6 detected by Y2H xref: IntAct:EBI-944708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:I0006721 name: p300-tfap2a-7 physical interaction comment: Interaction between human p300 and TFAP2A detected by mammalian two-hybrid xref: IntAct:EBI-938489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0006722 name: disc1-atf5-6 colocalization comment: Colocalisation reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-930690 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006723 name: disc1-tubg colocalization comment: Colocalisation of DISC1 protein and gamma tubulin protein xref: IntAct:EBI-930597 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001548 ! TBG1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006724 name: p300-tfap2a-2 physical interaction comment: Interaction between human p300 and TFAP2A detected by mammalian two-hybrid xref: IntAct:EBI-937812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0006725 name: p300-tfap2a-3 physical interaction comment: Interaction between human p300 and TFAP2A detected by mammalian two-hybrid xref: IntAct:EBI-937827 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0006726 name: p300-tfap2a-4 physical interaction comment: Interaction between human p300 and TFAP2A detected by mammalian two-hybrid xref: IntAct:EBI-937855 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0006727 name: p300-tfap2a-5 physical interaction comment: Interaction between human p300 and TFAP2A detected by mammalian two-hybrid xref: IntAct:EBI-937867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0006728 name: abl1-sorbs-2 physical interaction comment: Interaction between SORB1 and ABL1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-624126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:I0006729 name: pb1-arid2-2 physical interaction comment: coIP: bait = baf180; prey = baf200 xref: IntAct:EBI-637836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0006730 name: nek2-nek11-6 physical interaction comment: Interaction between NEK2A and NEK11 demonstrated by GST-pulldown xref: IntAct:EBI-633287 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN [Term] id: CCO:I0006731 name: sept1-aurkb-4 physical interaction comment: Colocalization of Septin1 and Aurora-B identified by colocalization xref: IntAct:EBI-693043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:I0006732 name: actn2-ttn-4 physical interaction comment: Interaction of Titin with alpha Actinin 2 does not depend on Actinin dimer formation, as detected by crosslinking. xref: IntAct:EBI-698651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0006733 name: ttn-ttn-1 physical interaction comment: Intra-molecular binding of Titin, as detected by yeast two hybrid. xref: IntAct:EBI-681275 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN [Term] id: CCO:I0006734 name: wrn-rpa1-2 physical interaction comment: In vitro pull-down: bait = WRN, prey = human Replication Protein A RPA70 (70kDa subunit) xref: IntAct:EBI-707161 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006735 name: wrn-rpa1-3 physical interaction comment: In vitro pull-down: bait = WRN, prey = human Replication Protein A RPA70 (70kDa subunit) xref: IntAct:EBI-707182 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006736 name: wrn-rpa1-4 physical interaction comment: In vitro pull-down: bait = WRN, prey = human Replication Protein A RPA70 (70kDa subunit) xref: IntAct:EBI-707195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006737 name: ccnd2-cdk4-1 physical interaction comment: Interaction between cyclin D2 and CDK4 demonstrated by coimmunoprecipitation xref: IntAct:EBI-768365 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001573 ! CCND2_HUMAN [Term] id: CCO:I0006738 name: ccnd2-cdk4-2 physical interaction comment: Interaction between cyclin D3 and CDK4 demonstrated by coimmunoprecipitation xref: IntAct:EBI-768369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN [Term] id: CCO:I0006739 name: hd53-hd53-2 physical interaction comment: Homodimerisation of human D53 detected by Y2H xref: IntAct:EBI-782691 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN [Term] id: CCO:I0006740 name: hd53-hd53-3 physical interaction comment: Interaction between human D53 and human D53 isoform detected by Y2H xref: IntAct:EBI-782699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0005643 ! O43397_HUMAN [Term] id: CCO:I0006741 name: hd53-hd53-4 physical interaction comment: Interaction between human D53 and partial human D53 detected by Y2H xref: IntAct:EBI-782702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN [Term] id: CCO:I0006742 name: pml-suv39h1-2 physical interaction comment: Interaction between PML and Myc-SUV39H1 was determined by CoIP xref: IntAct:EBI-870893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005644 ! Q9BWP7_HUMAN [Term] id: CCO:I0006743 name: ttn-obscn-3 physical interaction xref: IntAct:EBI-966813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005645 ! OBSCN_HUMAN [Term] id: CCO:I0006744 name: fgfbp1-fgf2-3 direct interaction comment: Interaction between FGFBP1 and FGF2 identified by SPR xref: IntAct:EBI-977796 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0005646 ! FGFP1_HUMAN [Term] id: CCO:I0006745 name: dusp1-ubiq-1 ubiquitination comment: Ubiquitination of DUSP1demonstrated by coimmunoprecipitation xref: IntAct:EBI-975570 is_a: CCO:Y0000026 ! ubiquitination reaction relationship: has_participant CCO:B0001566 ! DUS1_HUMAN relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN [Term] id: CCO:I0006746 name: dusp1-skp2-1 physical interaction comment: Interaction between DUSP1 and SKP2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-975591 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001566 ! DUS1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:I0006747 name: dusp1-skp2-2 physical interaction comment: Interaction between DUSP1 and SKP2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-975605 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001566 ! DUS1_HUMAN relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:I0006748 name: brca1-trrap-2 physical interaction comment: Interaction detected by Coip. xref: IntAct:EBI-896489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN [Term] id: CCO:I0006749 name: brca1-trrap-3 physical interaction comment: Interaction detected by Coip. xref: IntAct:EBI-896498 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN [Term] id: CCO:I0006750 name: zwint_zw10_2 colocalization comment: colocalization of zwint and zw10 by immunofluorescence microscopy xref: IntAct:EBI-1001292 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006751 name: mad1l1_zw10_1 colocalization comment: colocalization of mad1 and zw10 by immunofluorescence microscopy xref: IntAct:EBI-1001430 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN [Term] id: CCO:I0006752 name: zw10_bub1_1 colocalization comment: colocalization of zw10 and bub1 by immunofluorescence microscopy xref: IntAct:EBI-1001434 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001395 ! BUB1_HUMAN [Term] id: CCO:I0006753 name: zw10_bub1b_2 colocalization comment: colocalization of zw10 and bubr1 by immunofluorescence microscopy xref: IntAct:EBI-1001465 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN [Term] id: CCO:I0006754 name: zw10_dync1l1_1 colocalization comment: colocalization of zw10 and dync1l1 by immunofluorescence microscopy xref: IntAct:EBI-1001469 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0005648 ! DC1I1_HUMAN [Term] id: CCO:I0006755 name: kntc2_zwint_4 colocalization comment: colocalization of kntc2 and zwint xref: IntAct:EBI-1001599 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006756 name: zw10_zwint_1 colocalization comment: colocalization of zw10 and zwint xref: IntAct:EBI-1001608 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006757 name: kntc2_zw10_2 colocalization comment: colocalization of kntc2 and zw10 xref: IntAct:EBI-1001614 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN [Term] id: CCO:I0006758 name: sgol1-ppp2ca-1 physical interaction xref: IntAct:EBI-989140 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN [Term] id: CCO:I0006759 name: sgol1-ppm1a-1 physical interaction xref: IntAct:EBI-989168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0005649 ! PPM1A_HUMAN [Term] id: CCO:I0006760 name: sgol1-ppp2r5a-1 physical interaction xref: IntAct:EBI-989173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0006761 name: sgol2-ppp2ca-1 physical interaction xref: IntAct:EBI-989242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0001840 ! SGOL2_HUMAN [Term] id: CCO:I0006762 name: sgol2-ppm1a-1 physical interaction xref: IntAct:EBI-989247 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001840 ! SGOL2_HUMAN relationship: has_participant CCO:B0005649 ! PPM1A_HUMAN [Term] id: CCO:I0006763 name: usp7-tp53-5 physical interaction xref: IntAct:EBI-997494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0006764 name: kntc2-spbc24-3 physical interaction xref: IntAct:EBI-1000134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0006765 name: kntc2-spbc25-4 physical interaction xref: IntAct:EBI-1000323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0006766 name: shoc2-erbb2ip-2 physical interaction xref: IntAct:EBI-994081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0005650 ! SHOC2_HUMAN [Term] id: CCO:I0006767 name: skp1a-skp2-1 direct interaction comment: Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex xref: IntAct:EBI-1030257 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006768 name: skp1a-skp2-2 direct interaction comment: Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex xref: IntAct:EBI-1030268 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006769 name: skp1a-skp2-3 direct interaction comment: Insights into scf ubiquitin ligases from the structure of xref: IntAct:EBI-1030279 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006770 name: ccna2-cdk2-3 direct interaction comment: The structure of cdk2/cyclin a in complex with an oxindole inhibitor xref: IntAct:EBI-1030422 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006771 name: lig4-xrcc4-1 direct interaction comment: Crystal structure of a xrcc4-dna ligase iv complex xref: IntAct:EBI-1032322 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0005651 ! XRCC4_HUMAN [Term] id: CCO:I0006772 name: brca1-esr1 physical interaction xref: IntAct:EBI-1025255 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006773 name: esr1-brca1-10 physical interaction xref: IntAct:EBI-1025302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006774 name: brca1-esr1-2 physical interaction xref: IntAct:EBI-1025311 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006775 name: esr1-brca1-11 physical interaction xref: IntAct:EBI-1025336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006776 name: ran-ranbp1-1 physical interaction comment: Crystal structure of ran-gppnhp-ranbp1-rangap complex xref: IntAct:EBI-1032926 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:I0006777 name: ran-ranbp1-2 physical interaction comment: Crystal structure of ran-gdp-alfx-ranbp1-rangap complex xref: IntAct:EBI-1032940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005653 ! RANG_HUMAN [Term] id: CCO:I0006778 name: lkb1-strad-7 phosphorylation comment: Phosphorylation of STRAD by LKB1 xref: IntAct:EBI-1109451 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:I0006779 name: lkb1-strad-8 phosphorylation comment: Phosphorylation of STRAD by LKB1 xref: IntAct:EBI-1109485 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:I0006780 name: tp53-fbxo11-2 direct interaction comment: Interaction between p53 and FBX011 identified by pulldown xref: IntAct:EBI-1168039 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005332 ! FBX11_HUMAN [Term] id: CCO:I0006781 name: ctcf-chd8-3 physical interaction xref: IntAct:EBI-1169187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:I0006782 name: ctcf-chd8-4 colocalization xref: IntAct:EBI-1169201 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0005444 ! CHD8_HUMAN [Term] id: CCO:I0006783 name: rad21-stag2 physical interaction xref: IntAct:EBI-1175754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN [Term] id: CCO:I0006784 name: myc-snip1 physical interaction comment: SNIP1 coimmunoprecipitates with c-Myc in HEK293 cell lysate xref: IntAct:EBI-1189079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0006785 name: myc-skp2 physical interaction comment: SKP2 coimmunoprecipitates with c-Myc in HEK293 cell lysate xref: IntAct:EBI-1190080 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:I0006786 name: myc-fbxw7 physical interaction comment: FBW7 coimmunoprecipitates with c-Myc in HEK293 cell lysate xref: IntAct:EBI-1190099 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005654 ! FBXW7_HUMAN [Term] id: CCO:I0006787 name: myc-ep300 physical interaction comment: p300 coimmunoprecipitates with c-Myc in HEK293 cell lysate xref: IntAct:EBI-1190163 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:I0006789 name: uchl1-ube2i physical interaction comment: PGP9.5 interacts with UBC9 in a yeast two-hybrid assay xref: IntAct:EBI-1181901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005541 ! UCHL1_HUMAN [Term] id: CCO:I0006790 name: lck-med28-3 phosphorylation comment: Phosphorylation of MED28 by LCK xref: IntAct:EBI-1206933 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN [Term] id: CCO:I0006791 name: kntc2_zwint_1 physical interaction comment: Y2H: bait=kntc2, prey=zwint xref: IntAct:EBI-1001482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0006792 name: cdk6-cdkn2a-1 direct interaction comment: Mechanism of g1 cyclin dependent kinase inhibition from the structure of the cdk6-p16ink4a tumor suppressor complex xref: IntAct:EBI-1027142 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0006793 name: cdk6-cdkn2d-2 direct interaction comment: Mechanism of g1 cyclin dependent kinase inhibition from the structures cdk6-p19ink4d inhibitor complex xref: IntAct:EBI-1027153 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0006794 name: fkbp1a-frap1-1 direct interaction comment: The structure of the immunophilin-immunosuppressant fkbp12-(c16)-ethoxy rapamycin complex interacting with human frap xref: IntAct:EBI-1027706 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001611 ! FRAP_HUMAN relationship: has_participant CCO:B0005655 ! FKB1A_HUMAN [Term] id: CCO:I0006795 name: tp53-hdac1 physical interaction xref: IntAct:EBI-1029612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0006796 name: cul1-rbx1-6 direct interaction comment: Structure of the cul1-rbx1-skp1-f boxskp2 scf ubiquitin ligase complex xref: IntAct:EBI-1033288 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006797 name: cul1-cul1-7 physical interaction comment: Structure of the cul1-rbx1-skp1-f boxskp2 scf ubiquitin ligase complex xref: IntAct:EBI-1033299 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0006798 name: ccna2-cdk2-8 direct interaction comment: Structure of human thr160-phospho cdk2-cyclin a complexed with a 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitor xref: IntAct:EBI-1037045 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0006799 name: disc1-cdk5rap3 physical interaction xref: IntAct:EBI-1105538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002044 ! CK5P3_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006800 name: disc1-dctn1 physical interaction xref: IntAct:EBI-1105616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001779 ! DCTN1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006801 name: disc1-dnch1-1 physical interaction xref: IntAct:EBI-1105673 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001780 ! DYHC1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006802 name: disc1-macf1-1 physical interaction xref: IntAct:EBI-1106033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006803 name: disc1-ppp5c physical interaction xref: IntAct:EBI-1106247 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001662 ! PPP5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006804 name: disc1-ywhaq physical interaction xref: IntAct:EBI-1106571 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006805 name: esr1-mdm2 physical interaction xref: IntAct:EBI-1108217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006806 name: tp53-pias4-3 physical interaction xref: IntAct:EBI-1153708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0006807 name: h3-caf1 physical interaction xref: IntAct:EBI-1165514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001742 ! CAF1A_HUMAN relationship: has_participant CCO:B0001743 ! CAF1B_HUMAN relationship: has_participant CCO:B0005221 ! H31_HUMAN [Term] id: CCO:I0006808 name: cul4b-ddb1-2 physical interaction xref: IntAct:EBI-1177650 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:I0006809 name: cul4b-tle2 physical interaction xref: IntAct:EBI-1177657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:I0006810 name: ddb1-ddb2-1 physical interaction xref: IntAct:EBI-1177673 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005658 ! DDB2_HUMAN [Term] id: CCO:I0006811 name: cul4a-ddb2 physical interaction xref: IntAct:EBI-1177680 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0005658 ! DDB2_HUMAN [Term] id: CCO:I0006812 name: cul4a-cul4b physical interaction xref: IntAct:EBI-1177688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:I0006813 name: cul4a-eed physical interaction xref: IntAct:EBI-1177705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0043864 ! EED_HUMAN [Term] id: CCO:I0006814 name: cul4a-cul4b-1 physical interaction xref: IntAct:EBI-1177717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:I0006815 name: cul4a-cul4b-2 physical interaction xref: IntAct:EBI-1177737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005615 ! WDR5_HUMAN [Term] id: CCO:I0006816 name: cul4a-cul4b-3 physical interaction xref: IntAct:EBI-1177757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:I0006817 name: l2dtl-cul4b physical interaction xref: IntAct:EBI-1178576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:I0006818 name: tle2-ddb1-1 physical interaction xref: IntAct:EBI-1178596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:I0006819 name: rbbp5-cul4a physical interaction xref: IntAct:EBI-1178676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:I0006820 name: hif1a-vhl-1 physical interaction comment: GST-HIF-1 alpha pulls down VHL xref: IntAct:EBI-1179275 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:I0006821 name: brms1-hdac1 physical interaction comment: HDAC1 coimmunoprecipitates with BRMS1 xref: IntAct:EBI-1200240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0006822 name: brms1-hdac2 physical interaction comment: HDAC2 coimmunoprecipitates with BRMS1 xref: IntAct:EBI-1200256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0006823 name: brms1-hdac4 physical interaction comment: HDAC4 coimmunoprecipitates with BRMS1 xref: IntAct:EBI-1200276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN [Term] id: CCO:I0006824 name: brms1-hdac5 physical interaction comment: HDAC5 coimmunoprecipitates with BRMS1 xref: IntAct:EBI-1200285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0002244 ! HDAC5_HUMAN [Term] id: CCO:I0006825 name: brms1-hdac6 physical interaction comment: HDAC6 coimmunoprecipitates with BRMS1 xref: IntAct:EBI-1200294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN [Term] id: CCO:I0006826 name: ccne1-cdkn1b-1 physical interaction comment: Interaction between Cyclin E1 and CDKN1B (p27) by coimmunoprecipitation xref: IntAct:EBI-1201858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0006827 name: ccnd1-cdkn1b-2 physical interaction comment: Interaction between Cyclin D1 and CDKN1B (p27) by coimmunoprecipitation xref: IntAct:EBI-1201861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0006828 name: lck-med28-1 physical interaction comment: Interaction between Lck and MED28 identified by GST pulldown xref: IntAct:EBI-1206783 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN [Term] id: CCO:I0006829 name: ran-xpot-1 physical interaction comment: Interaction of the transport receptors with Ran determined by affinity chromatography. xref: IntAct:EBI-286729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0005663 ! TNPO1_HUMAN relationship: has_participant CCO:B0005664 ! XPOT_HUMAN relationship: has_participant CCO:B0005665 ! XPO7_HUMAN [Term] id: CCO:I0006830 name: prkci-pard6b-1 physical interaction comment: Interaction detected by GST-pull down. xref: IntAct:EBI-295441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0006831 name: prkcz-pard6b-1 physical interaction comment: Interaction detected by GST-pull down. xref: IntAct:EBI-295446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:I0006832 name: cdc42-pard6a-1 physical interaction comment: Interaction detected by GST pull down : bait =Pard6A, prey = cdc42 xref: IntAct:EBI-295494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0006833 name: cdc42-pard6b-1 physical interaction comment: Interaction detected by GST-pull down: bait = human par6dA, prey = human cdc42 xref: IntAct:EBI-295499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0006834 name: cdc42-pard6g-1 physical interaction comment: Interaction detected by GST-pull down : bait =par6Dg, prey = cdc42 xref: IntAct:EBI-295504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002112 ! PAR6G_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0006835 name: rac1-pard6a-1 physical interaction comment: Interaction detected by GST-pull down. xref: IntAct:EBI-295509 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0006836 name: rac1-pard6b-1 physical interaction comment: Interaction detected by GST-pull down. xref: IntAct:EBI-295514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0006837 name: rac1-pard6g-1 physical interaction comment: Interaction detected by GST-pull down. xref: IntAct:EBI-295519 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002112 ! PAR6G_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0006838 name: pard6b-rac1-2 physical interaction comment: Formation of the complex detected by GST pull down. xref: IntAct:EBI-295524 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0006839 name: pard6b-cdc42-5 physical interaction comment: Complex formation detected by GST pull down. xref: IntAct:EBI-295530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0006840 name: tgfbr2-daxx-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-296246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005542 ! TGFR2_HUMAN [Term] id: CCO:I0006841 name: brca2-rad51-2 physical interaction comment: Interaction of the BRC repeat with Rad51 determined and consensus sequence determined. xref: IntAct:EBI-297257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0006842 name: egfr-grb2-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0006843 name: sos1-cd2ap-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:I0006844 name: sos2-cd2ap-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298213 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN [Term] id: CCO:I0006845 name: tceb1-tceb2-vh1 physical interaction comment: Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function xref: IntAct:EBI-301276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN [Term] id: CCO:I0006846 name: daxx-slc2a4-3 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-367172 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005473 ! GTR4_HUMAN [Term] id: CCO:I0006847 name: cbfa-cbfb-1 physical interaction comment: Formation of CBFcomplex identified by mass spectrometry xref: IntAct:EBI-389797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001770 ! NFYC_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:I0006848 name: stau-loc84643-1 physical interaction comment: Characterization of Staufen 1 ribonucleoprotein complexes xref: IntAct:EBI-443534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001963 ! KIF2B_HUMAN relationship: has_participant CCO:B0005483 ! STAU1_HUMAN [Term] id: CCO:I0006849 name: lats1-cdc2-1 physical interaction comment: Interaction between human LATS1 and CDC2 demonstrated by co-immunoprecipitation xref: IntAct:EBI-444321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:I0006850 name: lats1-limk1-1 physical interaction comment: Interaction of human LATS1 and LIMK1 demonstrated by co-ip. xref: IntAct:EBI-444398 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:I0006851 name: lats1-limk1-2 physical interaction comment: Interaction of human LATS1 and LIMK1 demonstrated by co-ip. xref: IntAct:EBI-444450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:I0006852 name: rhog-elmo1-1 physical interaction comment: Elmo binds to RhoG-GTP in GST pull-down assay xref: IntAct:EBI-446573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001704 ! RHOG_HUMAN relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN [Term] id: CCO:I0006854 name: cdt1-gmnn-5 physical interaction comment: Interaction between CDT1 and Germinin detected by GST pull down xref: IntAct:EBI-457118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:I0006855 name: plk1-mcm7-1 physical interaction comment: polo-box domain containing kinase coimmunoprecipitate minichromosome maintainance protein MCM7 xref: IntAct:EBI-476782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:I0006856 name: plk1-mcm2-1 physical interaction comment: polo-box domain containing kinase coimmunoprecipitate minichromosome maintainance protein MCM2 xref: IntAct:EBI-476798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:I0006857 name: p53-crebbp-6 physical interaction comment: GST-pull down : bait = CBP (CREB binding protein); prey = P53 xref: IntAct:EBI-493370 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0006858 name: tnf-tnfrsf1a-2 physical interaction comment: TNFR1 membrane associated complex I shown by CoIP (anti- flag- TNF-alpha) in HT1080 cell line xref: IntAct:EBI-514525 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:I0006859 name: tnf-tnfrsf1a-3 physical interaction comment: TNFR1 membrane associated complex I shown by CoIP (anti- flag- TNF-alpha) in I-kBmut HT1080 cell line xref: IntAct:EBI-514572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:I0006860 name: tnf-tnfrsf1a-4 physical interaction comment: TNFR1 membrane associated complex I shown by CoIP (anti- Fc-TNF) in HT1080 cell line xref: IntAct:EBI-514589 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:I0006861 name: cdc2-ccnb1-1 physical interaction comment: Interaction of CDK1 and Cyclin B1 by coimmunopreciptiation xref: IntAct:EBI-515191 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN [Term] id: CCO:I0006862 name: cdk4-ccnd1-5 physical interaction comment: co-IP: bait = cdk4, prey = cyclin D1, prey = p21-CIP1 xref: IntAct:EBI-519497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0006863 name: cul1-skp1-5 physical interaction comment: Coimmunoprecipitaion reveals interaction between the culin1 protein and the S-phase kinase-associated protein 1 xref: IntAct:EBI-600016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:I0006864 name: cul1-skp2-2 physical interaction comment: Coimmunoprecipitaion reveals interaction between the culin1 protein and the S-phase kinase-associated protein 2 xref: IntAct:EBI-600023 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:I0006865 name: cand1-cul1-3 physical interaction comment: Coimmunoprecipitaion reveals interaction between the TIP120A (CAND1) protein and cullin1 protein xref: IntAct:EBI-600785 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006866 name: cul1-cand1-7 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein , TIP120A (CAND1) protein and RBX1 protein xref: IntAct:EBI-600789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006867 name: cul1-rbx1-5 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein and RBX1 protein xref: IntAct:EBI-600793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0006868 name: hcfc1-gabp2b1-2 physical interaction comment: GST pull-down of interaction between hcfc1 and gabp2b1. xref: IntAct:EBI-620481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0040683 ! GABP1_HUMAN [Term] id: CCO:I0006869 name: hcfc1-zbtb17-2 physical interaction comment: Co-ip (in-vivo) of interaction between hcfc1 and zbtb17 (Miz1) xref: IntAct:EBI-621550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0006870 name: nek2-nek11-2 colocalization comment: Interaction between NEK2 and NEK11 demonstrated by coimmunofluorescence xref: IntAct:EBI-633213 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN [Term] id: CCO:I0006871 name: nek2-nek11-5 physical interaction comment: Interaction between NEK2A and NEK11 demonstrated by coimmunoprecipitation xref: IntAct:EBI-633249 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN [Term] id: CCO:I0006872 name: eif2ak1-cdc37-8 physical interaction comment: Interaction between EIF2AK1 (HPI) and cdc37 demonstrated by coimmunoprecipitation xref: IntAct:EBI-640358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:I0006873 name: tp53-hipk1-2 physical interaction comment: Interacting regions of p53 and HIPK1 identified by Y2H xref: IntAct:EBI-692933 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005675 ! HIPK1_HUMAN [Term] id: CCO:I0006874 name: ttn-actn2-5 physical interaction comment: Interaction of Titin and alpha Actinin 2 binding regions detected by affinity techniques xref: IntAct:EBI-698792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0006875 name: wrn-terf2-4 direct interaction comment: Pull-down: bait= WRM, prey = TRF2 (TERF2) xref: IntAct:EBI-706693 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006876 name: wrn-terf2-5 direct interaction comment: Pull-down: bait= WRM, prey = TRF2 (TERF2) xref: IntAct:EBI-706703 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006877 name: wrn-terf2-6 direct interaction comment: Pull-down: bait= WRM, prey = TRF2 (TERF2) xref: IntAct:EBI-706714 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006878 name: wrn-terf2-7 direct interaction comment: Pull-down: bait= WRM, prey = TRF2 (TERF2) xref: IntAct:EBI-706726 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006879 name: blm-terf1-7 direct interaction comment: In vitro Co-IP: bait= TRF1 (TERF1) , prey = BLM xref: IntAct:EBI-711045 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0006880 name: blm-terf1-8 direct interaction comment: In vitro Co-IP: bait= TRF1 (TERF1) , prey = BLM helicase fragment xref: IntAct:EBI-711078 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0006881 name: blm-terf2-9 direct interaction comment: In vitro Co-IP: bait= TRF2 (TERF2) , prey = BLM helicase fragment xref: IntAct:EBI-711090 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0006882 name: blm-terf2-10 direct interaction comment: In vitro Co-IP: bait= TRF2 (TERF2) , prey = BLM c-terminus fragment xref: IntAct:EBI-711103 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0006883 name: bcl2-bcap31 physical interaction comment: Interaction of BCL-2 with p28Bap31 identified by Far Western xref: IntAct:EBI-77682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005676 ! BAP31_HUMAN [Term] id: CCO:I0006884 name: fshr-ywhaq-1 physical interaction comment: Y2H: bait= FSHR intracellular loop 1and 2, prey = 14-3-3 tau isoform xref: IntAct:EBI-848264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005506 ! FSHR_HUMAN [Term] id: CCO:I0006885 name: bcl_2-nip2-1 physical interaction comment: Interaction between human Bcl-2 and Nip2 detected by Y2H xref: IntAct:EBI-849945 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005677 ! BNIP2_HUMAN [Term] id: CCO:I0006886 name: bcl_2-nip3-1 physical interaction comment: Interaction between human Bcl-2 and Nip3 detected by Y2H xref: IntAct:EBI-849952 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN [Term] id: CCO:I0006887 name: brca1-trrap-6 physical interaction comment: Interaction detected by sucrose gradient. xref: IntAct:EBI-896611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN [Term] id: CCO:I0006888 name: eif4g2-eif4a1-1 direct interaction comment: Interaction between eIF4G2 and eIF4A1 demonstrated by His-pulldown xref: IntAct:EBI-927940 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001699 ! IF4G2_HUMAN relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN [Term] id: CCO:I0006889 name: disc1-atf5-3 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-929222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006890 name: cdc73-ctnnb1-4 physical interaction xref: IntAct:EBI-932449 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0006891 name: cited2-tfap2a-1 physical interaction comment: Interaction between human CITED2 and TFAP2A detected by far western xref: IntAct:EBI-937763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0006892 name: cited2-tfap2b-1 physical interaction comment: Interaction between human CITED2 and TFAP2B detected by far western xref: IntAct:EBI-937771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005680 ! AP2B_HUMAN [Term] id: CCO:I0006893 name: cited2-tfap2c-1 physical interaction comment: Interaction between human CITED2 and TFAP2C detected by far western xref: IntAct:EBI-937779 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005377 ! AP2C_HUMAN [Term] id: CCO:I0006894 name: s100a6-s100a6-1 physical interaction comment: Homodimerisation of human S100A6 detected by Y2H xref: IntAct:EBI-945542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001494 ! S10A6_HUMAN [Term] id: CCO:I0006895 name: s100a6-s100b-1 physical interaction comment: Interaction between human S100A6 and S100B detected by Y2H xref: IntAct:EBI-945546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0006896 name: s100b-s100a6-2 physical interaction comment: Interaction between human S100B and S100A6 detected by Y2H xref: IntAct:EBI-945556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0006897 name: sept5-sept11 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between SEPT5 protein and SEPT11 protein xref: IntAct:EBI-958008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002169 ! SEP11_HUMAN [Term] id: CCO:I0006898 name: sept5-sept8 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between SEPT5 protein and SEPT8 protein xref: IntAct:EBI-958054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002015 ! SEPT8_HUMAN relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN [Term] id: CCO:I0006899 name: sept11-sept5 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between SEPT11 protein and SEPT5 protein xref: IntAct:EBI-958078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002169 ! SEP11_HUMAN [Term] id: CCO:I0006900 name: atr-tp53-1 phosphorylation comment: Phosphorylation of p53 by ATR xref: IntAct:EBI-969043 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001756 ! ATR_HUMAN [Term] id: CCO:I0006901 name: mapk1-dusp1-3 phosphorylation comment: phosphorylation of DUSP1 (MKP-1) by MAPK1 xref: IntAct:EBI-975550 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001566 ! DUS1_HUMAN [Term] id: CCO:I0006902 name: ubp7-daxx-4 physical interaction xref: IntAct:EBI-992576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0006903 name: daxx-mdm2-1 physical interaction xref: IntAct:EBI-992923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006904 name: mbde-suv93h1-1 physical interaction xref: IntAct:EBI-994581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0006905 name: suv93h1-mbde-1 physical interaction xref: IntAct:EBI-994593 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0006906 name: suv93h1-mbd1-4 colocalization xref: IntAct:EBI-994708 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0006907 name: atr-creb1-1 phosphorylation comment: Phosphorylation of CREB1 by ATR xref: IntAct:EBI-998362 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001756 ! ATR_HUMAN relationship: has_participant CCO:B0005681 ! CREB1_HUMAN [Term] id: CCO:I0006908 name: kntc2-spbc25-3 physical interaction xref: IntAct:EBI-1000294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0006909 name: cenph_kntc2_2 physical interaction xref: IntAct:EBI-1003762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0005682 ! CENPH_HUMAN [Term] id: CCO:I0006910 name: cenph_kntc2_4 physical interaction xref: IntAct:EBI-1003789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0005682 ! CENPH_HUMAN [Term] id: CCO:I0006911 name: dcp1a-rcd8-xrn1 colocalization xref: IntAct:EBI-1006344 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001954 ! XRN1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0005683 ! EDC4_HUMAN [Term] id: CCO:I0006912 name: tcf7l2-ctnnb1-2 physical interaction xref: IntAct:EBI-1017836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:I0006913 name: tcf7l2-ctnnb1-4 physical interaction xref: IntAct:EBI-1018277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0006914 name: esr1-brca1-5 direct interaction xref: IntAct:EBI-1024954 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006915 name: esr1-brca1-7 direct interaction xref: IntAct:EBI-1025098 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006916 name: raf1-rap1a-1 direct interaction comment: Crystal structure of rap.gmppnp in complex with the ras- binding-domain of c-raf1 kinase (rafrbd). xref: IntAct:EBI-1026035 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0006917 name: nfya-tp53 physical interaction xref: IntAct:EBI-1031191 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006918 name: nfya-tp53-1 physical interaction xref: IntAct:EBI-1032019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006919 name: tp53-nfya-5 physical interaction xref: IntAct:EBI-1036989 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006920 name: tp53-nfya-6 physical interaction xref: IntAct:EBI-1040817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006921 name: nfya-tp53-2 physical interaction xref: IntAct:EBI-1040859 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0006922 name: abl1-rin1-1 physical interaction comment: Interaction between Abl1 and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0006923 name: abl1-rin1-2 physical interaction comment: Interaction between Abl1 and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0006924 name: abl2-rin1-5 physical interaction comment: Interaction between Abl2, Hras and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN relationship: has_participant CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:I0006925 name: esr1-mdm2-1 physical interaction xref: IntAct:EBI-1108256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0006926 name: p53-mdm2-2 physical interaction xref: IntAct:EBI-1108409 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0006927 name: stk11-strad-6 colocalization comment: Interaction between STRAD and STK11 (LKB1) determined by coimmunoprecipitation xref: IntAct:EBI-1109785 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:I0006928 name: hnrpd-ube2i-2 physical interaction xref: IntAct:EBI-1110491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:I0006929 name: dj_1-daxx-3 colocalization xref: IntAct:EBI-1164517 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005443 ! PARK7_HUMAN [Term] id: CCO:I0006930 name: smc2-hp1 colocalization xref: IntAct:EBI-1175572 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:I0006931 name: cul4b-ddb1 physical interaction xref: IntAct:EBI-1176116 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN relationship: has_participant CCO:B0005687 ! GRWD1_HUMAN relationship: has_participant CCO:B0005688 ! WDR82_HUMAN relationship: has_participant CCO:B0005689 ! WDR26_HUMAN relationship: has_participant CCO:B0005690 ! TLE3_HUMAN relationship: has_participant CCO:B0005691 ! SMU1_HUMAN [Term] id: CCO:I0006932 name: cacna1c-cam-1 physical interaction comment: Calmodulin binds to the C-terminal domain of alpha1 1.2. xref: IntAct:EBI-1184894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005692 ! CAC1C_HUMAN [Term] id: CCO:I0006933 name: cacna1c-cam-2 physical interaction comment: Calmodulin binds to the C-terminal domain of alpha1 1.2. xref: IntAct:EBI-1184912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005692 ! CAC1C_HUMAN [Term] id: CCO:I0006934 name: snip1-myc-3 physical interaction comment: GST-SNIP1 pulls down c-Myc xref: IntAct:EBI-1189199 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0006935 name: myc-snip1-2 physical interaction comment: GST-c-Myc pulls down SNIP1 xref: IntAct:EBI-1189228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0006936 name: brms1-arid4a physical interaction comment: BRMS1 interacts with RBBP1 (ARID4A) in a yeast two-hybrid assay xref: IntAct:EBI-1199917 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005693 ! ARI4A_HUMAN [Term] id: CCO:I0006937 name: brms1-sds3 physical interaction comment: BRMS1 interacts with SDS3 in a yeast two-hybrid assay xref: IntAct:EBI-1199922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:I0006938 name: brms1-smarce1 physical interaction comment: BRMS1 interacts with BAF57 (SMARCE1) in a yeast two-hybrid assay xref: IntAct:EBI-1199928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN [Term] id: CCO:I0006939 name: brms1-taf1 physical interaction comment: BRMS1 interacts with CCG1 (TAF1) in a yeast two-hybrid assay xref: IntAct:EBI-1199934 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN [Term] id: CCO:I0006940 name: brms1-nmi physical interaction comment: BRMS1 interacts with NMI in a yeast two-hybrid assay xref: IntAct:EBI-1199942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0006941 name: brms1-dnajb6 physical interaction comment: BRMS1 interacts with MRJ (DNAJB6) in a yeast two-hybrid assay xref: IntAct:EBI-1199948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005696 ! DNJB6_HUMAN [Term] id: CCO:I0006942 name: brms1-kpna5 physical interaction comment: BRMS1 interacts with KPNA5 in a yeast two-hybrid assay xref: IntAct:EBI-1200000 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005697 ! IMA5_HUMAN [Term] id: CCO:I0006943 name: brms1-hspa8 physical interaction comment: BRMS1 interacts HSP70 and HSP90alpha in MDA-MB-231 lysates xref: IntAct:EBI-1200006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0006944 name: cdkn1b-lyn-2 phosphorylation comment: Phosphorylation of CDKN1B (p27) by lyn xref: IntAct:EBI-1201690 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:I0006945 name: cdkn1b-abl-2 phosphorylation comment: Phosphorylation of CDKN1B (p27) by murine c-Abl xref: IntAct:EBI-1201742 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0006946 name: daxx-cenpc1-1 physical interaction comment: Interaction of deletion constructs detected by Y2H. xref: IntAct:EBI-295810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005470 ! CENPC_HUMAN [Term] id: CCO:I0006947 name: daxx-pml-2 colocalization comment: Colocalization detected by confocal microscopy. xref: IntAct:EBI-295919 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0006948 name: brca2-rad51-1 physical interaction comment: Interaction detected by crystallography. xref: IntAct:EBI-297231 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0006949 name: dek-daxx-1 physical interaction comment: Dek, Daxx, HDAC and H4 complex detected by Co-fractionation. xref: IntAct:EBI-297600 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005342 ! DEK_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005700 ! H4_HUMAN [Term] id: CCO:I0006950 name: hdac6-hdac11-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-297951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN relationship: has_participant CCO:B0005701 ! HDA11_HUMAN [Term] id: CCO:I0006951 name: stk4-rassf5-1 physical interaction comment: Interaction of MST1 and NORE1 identified by co-immunoprecipitation xref: IntAct:EBI-367398 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002008 ! RASF5_HUMAN relationship: has_participant CCO:B0005702 ! STK4_HUMAN [Term] id: CCO:I0006952 name: cbfa-cbfb physical interaction comment: Components of the CBF complex confirmed by coimmunoprecipitation xref: IntAct:EBI-389809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001770 ! NFYC_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:I0006953 name: abi1-nckap1-1 physical interaction xref: IntAct:EBI-389836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:I0006954 name: lats1-zyx-1 physical interaction comment: Interaction betwen human LATS1 and ZYX identified by Y2H xref: IntAct:EBI-444208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0006955 name: plk1-mcm7-2 physical interaction comment: deletion analysis of PLK1 interacting with MCM7 xref: IntAct:EBI-476813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:I0006956 name: plk1-mcm3-1 physical interaction comment: deletion analysis of PLK1 interacting with MCM3 xref: IntAct:EBI-476822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:I0006957 name: plk1-mcm7-4 physical interaction comment: Interaction between endogenous PLK1 and MINC7 xref: IntAct:EBI-476841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:I0006958 name: sirt2-pcaf-myod1-2 physical interaction comment: Interaction between SIRT2, PCAF, MYOD1 detected by CoIP. xref: IntAct:EBI-489310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005705 ! MYOD1_HUMAN [Term] id: CCO:I0006959 name: pkmyt1-cdc2-1 phosphorylation xref: IntAct:EBI-495348 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:I0006960 name: mdc1-atm-1 physical interaction xref: IntAct:EBI-495489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0001788 ! MDC1_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN relationship: has_participant CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:I0006961 name: nbs1-mdc1-1 physical interaction xref: IntAct:EBI-495603 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:I0006962 name: nbs1-atm-1 physical interaction xref: IntAct:EBI-495607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0001788 ! MDC1_HUMAN [Term] id: CCO:I0006963 name: map4k2-mlk3-1 physical interaction comment: Interaction of GCK with MLK3 xref: IntAct:EBI-49968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001820 ! M3K11_HUMAN relationship: has_participant CCO:B0005706 ! M4K2_HUMAN [Term] id: CCO:I0006964 name: hvem-lt_alpha physical interaction comment: G protein pull down reveals the tumor necrosis factor receptor superfamily member 14 precursor protein (HVEM) intercts with the lymphotoxin-alpha precursor protein xref: IntAct:EBI-524101 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0005707 ! TNR14_HUMAN [Term] id: CCO:I0006965 name: araf-pbk physical interaction comment: Y2H: bait = A-Raf ,prey = TOPK/BPK-MPAKK-like protein kinase cap site form 2 xref: IntAct:EBI-536978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002045 ! TOPK_HUMAN relationship: has_participant CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:I0006966 name: gnai1-numa1-1 physical interaction xref: IntAct:EBI-618676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN [Term] id: CCO:I0006967 name: gnai1-gpsm2-3 physical interaction xref: IntAct:EBI-618729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN [Term] id: CCO:I0006968 name: gpsm2-numa1-1 physical interaction xref: IntAct:EBI-618735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0006969 name: tacc1-tdrd7-8 physical interaction comment: Interaction between TACC1 and TDRD1 (TRAP) confirmed by coimmunopreciptiation xref: IntAct:EBI-624734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0005496 ! TDRD7_HUMAN [Term] id: CCO:I0006970 name: huew1-tp53-1 physical interaction comment: coIP: bait = arf-bp1/mule, prey = tp53 xref: IntAct:EBI-626167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:I0006971 name: tp53-huew1-2 physical interaction comment: coIP: bait = tp53, prey = arf-bp1/mule xref: IntAct:EBI-626197 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:I0006972 name: hcfc1-many-3 physical interaction comment: interaction cosedimentation of Hcfc1, Sin3A, Ash2 and Sp1 in high-molecular-weight complexes xref: IntAct:EBI-630079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN [Term] id: CCO:I0006973 name: hcfc1-zf-1 physical interaction comment: Y2H of interaction between hcfc1 and zf xref: IntAct:EBI-632984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0006974 name: hcfc1-zf-3 physical interaction comment: Mammalian two-hybrid assay of interaction between hcfc1 and zf xref: IntAct:EBI-633091 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0006975 name: nek2-nek11-1 colocalization comment: Interaction between NEK2 and NEK11 demonstrated by coimmunofluorescence xref: IntAct:EBI-633181 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN [Term] id: CCO:I0006976 name: nek2-nek11-7 phosphorylation comment: NEK2A phosphorylates NEK11 xref: IntAct:EBI-633306 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN [Term] id: CCO:I0006977 name: smarca4-pb1-arid2-2 physical interaction comment: PBAF complex subunits by CoIp xref: IntAct:EBI-638271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN [Term] id: CCO:I0006978 name: egfr-pik3c2b-2 physical interaction comment: Interaction of PIK3C2B and EGFR demonstrated by coimmunoprecipitation xref: IntAct:EBI-641198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN [Term] id: CCO:I0006979 name: egfr-pik3c2b-5 physical interaction comment: Interaction of PIK3C2B and EGFR demonstrated by coimmunoprecipitation xref: IntAct:EBI-641326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN [Term] id: CCO:I0006980 name: gnl3-p53 physical interaction comment: Coimmunoprecipitaion reveals interaction between the nucleostemin protein and P53 protein xref: IntAct:EBI-641720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0002103 ! GNL3_HUMAN [Term] id: CCO:I0006981 name: wrn-terf2-2 physical interaction comment: Co-IP: bait = WRM, prey = TRF2 (TERF2) xref: IntAct:EBI-706668 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0006982 name: tcfcl1-ruvbl1 physical interaction comment: Phosphocellulose chromatography reveals complex of TCFCL1, RUVBL1 and HTAT1P proteins xref: IntAct:EBI-777788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN [Term] id: CCO:I0006983 name: tcfcl1-ruvbl1-1 physical interaction comment: Phosphocellulose chromatography reveals complex of TCFCL1and RUVBL1 proteins xref: IntAct:EBI-777793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN [Term] id: CCO:I0006984 name: tcfcl1-ruvbl1-2 physical interaction comment: Phosphocellulose chromatography reveals complex of TCFCL1and RUVBL1 proteins xref: IntAct:EBI-777798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN [Term] id: CCO:I0006985 name: tcfcl1-ruvbl1-3 physical interaction comment: Phosphocellulose chromatography reveals complex of TCFCL1and RUVBL1 proteins xref: IntAct:EBI-777802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN [Term] id: CCO:I0006986 name: tgfb2-bapp-2 physical interaction comment: Interaction between transforming growth factor beta and beta amyloid precursor protein detected by chromatography xref: IntAct:EBI-779611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006987 name: tgfb2-bapp-3 physical interaction comment: Interaction between transforming growth factor beta and beta amyloid precursor protein detected by co-IP xref: IntAct:EBI-779619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006988 name: adam17-mad2l1-1 physical interaction xref: IntAct:EBI-78212 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:I0006989 name: adam17-mad2l1-3 physical interaction xref: IntAct:EBI-78246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:I0006990 name: p53-pml-1 physical interaction comment: Interaction between human p53 and human PML detected by coIP xref: IntAct:EBI-782798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001570 ! PML_HUMAN [Term] id: CCO:I0006991 name: hrmt1l2-ilf3-2 methylation comment: Coimmunoprecipitation of components. xref: IntAct:EBI-78793 is_a: CCO:Y0000021 ! methylation reaction relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0005713 ! ANM1_HUMAN [Term] id: CCO:I0006992 name: apbb2 -app-1 physical interaction comment: APP-APBB2 (FE65L) xref: IntAct:EBI-79291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0006993 name: bnip3alpha-bcl_2-1 direct interaction comment: Interaction between human BNIP3alpha and Bcl-2 detected by GST pulldown xref: IntAct:EBI-850662 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:I0006994 name: bnip3alpha-bcl_2-2 direct interaction comment: Interaction between human BNIP3alpha deletion and Bcl-2 detected by GST pulldown xref: IntAct:EBI-850700 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:I0006995 name: fbxo5-plk1 phosphorylation comment: Interaction between PLK1 and Emi1 is inhibited by Evi5 N terminus. xref: IntAct:EBI-865692 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN [Term] id: CCO:I0006996 name: fbxo5-plk1-1 phosphorylation comment: Interaction between PLK1 and Emi1 xref: IntAct:EBI-866028 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN [Term] id: CCO:I0006997 name: disc1-atf5 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-928728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006998 name: disc1-atf5-5 physical interaction comment: Coimmunoprecipitation reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-930487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0006999 name: cdc73-ctnnb1 physical interaction xref: IntAct:EBI-932234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007000 name: cdc73-tcf4 physical interaction xref: IntAct:EBI-932378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005715 ! ITF2_HUMAN [Term] id: CCO:I0007001 name: hras1-rassf5-2 physical interaction xref: IntAct:EBI-960623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0002008 ! RASF5_HUMAN [Term] id: CCO:I0007002 name: rap1a-itgal-1 physical interaction xref: IntAct:EBI-961074 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0002008 ! RASF5_HUMAN [Term] id: CCO:I0007003 name: e2f3-rb physical interaction comment: Pulldown analysis reveals interaction between E2F3 protein and retinoblastoma-associated protein xref: IntAct:EBI-965909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN [Term] id: CCO:I0007004 name: ttn-obscn-1 physical interaction xref: IntAct:EBI-966774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005645 ! OBSCN_HUMAN [Term] id: CCO:I0007005 name: myc-zbtb17-1 physical interaction xref: IntAct:EBI-975455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007006 name: myc-zbtb17-2 physical interaction xref: IntAct:EBI-975466 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007007 name: myc-max physical interaction xref: IntAct:EBI-975474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:I0007008 name: e2f3-rb-1 physical interaction comment: Pulldown analysis reveals interaction between E2F3 protein and retinoblastoma-associated protein xref: IntAct:EBI-987168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN [Term] id: CCO:I0007009 name: e2f3-rb-2 physical interaction comment: Pulldown analysis reveals interaction between E2F3 protein and retinoblastoma-associated protein xref: IntAct:EBI-987184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN [Term] id: CCO:I0007010 name: brca2-rad51-9 physical interaction comment: Interaction between BRCA2 and RAD51 determined by GST-pulldown xref: IntAct:EBI-987396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007011 name: tcf7l2-ctnnb1 physical interaction xref: IntAct:EBI-989553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0007012 name: smc1-mcm7-4 direct interaction comment: Interaction between human Smc1 and MCM7 detected by pulldown xref: IntAct:EBI-1004745 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0007013 name: smc1-mcm7-5 direct interaction comment: Interaction between human Smc1 and MCM7 detected by pulldown xref: IntAct:EBI-1004758 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0007014 name: upf1-dcp1a physical interaction xref: IntAct:EBI-1006512 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN [Term] id: CCO:I0007015 name: upf1-dcp2 physical interaction xref: IntAct:EBI-1006558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005433 ! DCP2_HUMAN [Term] id: CCO:I0007016 name: upf1-rcd8 physical interaction xref: IntAct:EBI-1006676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0005683 ! EDC4_HUMAN relationship: has_participant CCO:B0005717 ! EDC3_HUMAN [Term] id: CCO:I0007017 name: brca1-esr1-4 direct interaction xref: IntAct:EBI-1024926 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0007018 name: brca1-esr1-5 direct interaction xref: IntAct:EBI-1025157 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0007019 name: acaca-brca1-1 physical interaction xref: IntAct:EBI-1025400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:I0007020 name: flt1-vegf-1 direct interaction comment: Vegf in complex with domain 2 of the flt-1 receptor xref: IntAct:EBI-1026762 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:I0007021 name: stk6-tpx2-1 direct interaction comment: Structure of aurora-a 122-403, phosphorylated on thr287, thr288 and bound to tpx2 1-43 xref: IntAct:EBI-1037348 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0002227 ! TPX2_HUMAN [Term] id: CCO:I0007022 name: appbp1-nedd8-1 physical interaction comment: Appbp1-uba3-nedd8, an e1-ubiquitin-like protein complex xref: IntAct:EBI-1037683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0001989 ! UBA3_HUMAN relationship: has_participant CCO:B0005331 ! NEDD8_HUMAN [Term] id: CCO:I0007023 name: appbp1-nedd8-2 physical interaction comment: Appbp1-uba3-nedd8, an e1-ubiquitin-like protein complex with atp xref: IntAct:EBI-1037697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0001989 ! UBA3_HUMAN relationship: has_participant CCO:B0005331 ! NEDD8_HUMAN [Term] id: CCO:I0007024 name: apc-ctnnb1-3 direct interaction comment: Beta-catenin in complex with a phosphorylated apc 20aa repeat fragment xref: IntAct:EBI-1040010 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007025 name: tacc1-yeats4-1 physical interaction xref: IntAct:EBI-1151284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN [Term] id: CCO:I0007026 name: tacc1-yeats4-2 physical interaction xref: IntAct:EBI-1151300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN [Term] id: CCO:I0007027 name: tp53-pias4-2 physical interaction xref: IntAct:EBI-1153677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0007028 name: msh2-msh3 physical interaction comment: GST-MSH2 pull down of MSH3 xref: IntAct:EBI-1164225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005720 ! MSH3_HUMAN [Term] id: CCO:I0007029 name: msh3-msh2-1 physical interaction comment: GST-MSH3 pull down of MSH2 xref: IntAct:EBI-1164243 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005720 ! MSH3_HUMAN [Term] id: CCO:I0007030 name: msh2-msh6 physical interaction comment: GST-MSH2 pull down of MSH6 xref: IntAct:EBI-1164258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:I0007031 name: msh6-msh2 physical interaction comment: GST-MSH6 pull down of MSH2 xref: IntAct:EBI-1164270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:I0007032 name: msh2-msh2 physical interaction comment: MSH2 homodimerisation xref: IntAct:EBI-1164319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN [Term] id: CCO:I0007033 name: msh3-msh2-2 physical interaction comment: GST-MSH3 pull down of MSH2 xref: IntAct:EBI-1164887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005720 ! MSH3_HUMAN [Term] id: CCO:I0007034 name: msh6-msh2-1 physical interaction comment: GST-MSH6 pull down of MSH2 xref: IntAct:EBI-1164907 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:I0007035 name: msh3-msh2-3 physical interaction comment: GST-MSH3 pull down of MSH2 xref: IntAct:EBI-1164925 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005720 ! MSH3_HUMAN [Term] id: CCO:I0007036 name: wapl-cspg6 physical interaction xref: IntAct:EBI-1175094 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007037 name: wapl-cspg6-3 physical interaction xref: IntAct:EBI-1175276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007038 name: smc2l1-smc4l1 physical interaction xref: IntAct:EBI-1175303 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0002168 ! SMC4_HUMAN [Term] id: CCO:I0007039 name: wapl-cspg6-1 physical interaction xref: IntAct:EBI-1175624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007040 name: wapl-cspg6-2 physical interaction xref: IntAct:EBI-1175636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007041 name: chek2-aatf physical interaction comment: Che-1 coimmunoprecipitates with Chk2 xref: IntAct:EBI-1180881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0007044 name: cdn1b-cops5 colocalization comment: p27 colocalizes with JAB1 in H1299 cells xref: IntAct:EBI-1182050 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0002025 ! CSN5_HUMAN [Term] id: CCO:I0007045 name: cdn1b-uchl1 colocalization comment: p27 colocalizes with PGP9.5 in H1299 cells xref: IntAct:EBI-1182061 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005541 ! UCHL1_HUMAN [Term] id: CCO:I0007046 name: nmi-stat5b-1 physical interaction comment: Interaction between human Nmi and Stat5b detected by coIP xref: IntAct:EBI-1186157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007047 name: stat5b-nmi-2 physical interaction comment: Interaction between human Stat5b and Nmi detected by coIP xref: IntAct:EBI-1186168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007048 name: nmi-stat5b-2 physical interaction comment: Interaction between human Nmi and Stat5b detected by coIP xref: IntAct:EBI-1186179 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007049 name: nmi-stat5b-3 physical interaction comment: Interaction between human Nmi and Stat5b detected by pulldown xref: IntAct:EBI-1186374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007050 name: nmi-stat1-1 physical interaction comment: Interaction between human Nmi and Stat1 detected by pulldown xref: IntAct:EBI-1186434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007051 name: mit1a-ef1-fila physical interaction xref: IntAct:EBI-1188258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001563 ! CALR_HUMAN relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN relationship: has_participant CCO:B0005723 ! MTR1A_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0005845 ! LRC59_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0028238 ! ROA0_HUMAN relationship: has_participant CCO:B0030269 ! GNAI3_HUMAN relationship: has_participant CCO:B0032549 ! RAB10_HUMAN relationship: has_participant CCO:B0041405 ! Q60FE5_HUMAN relationship: has_participant CCO:B0051023 ! PGRC1_HUMAN relationship: has_participant CCO:B0051815 ! IRS4_HUMAN relationship: has_participant CCO:B0054746 ! VAPB_HUMAN relationship: has_participant CCO:B0055621 ! GBB1_HUMAN relationship: has_participant CCO:B0058769 ! GBB4_HUMAN relationship: has_participant CCO:B0063067 ! CALX_HUMAN relationship: has_participant CCO:B0063255 ! CN37_HUMAN relationship: has_participant CCO:B0063256 ! TMM33_HUMAN relationship: has_participant CCO:B0063257 ! PDIA6_HUMAN [Term] id: CCO:I0007052 name: mit1b-ef1-fila-1 physical interaction xref: IntAct:EBI-1188355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001375 ! PPM1G_HUMAN relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN relationship: has_participant CCO:B0005724 ! MTR1B_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0030269 ! GNAI3_HUMAN relationship: has_participant CCO:B0041405 ! Q60FE5_HUMAN relationship: has_participant CCO:B0051815 ! IRS4_HUMAN relationship: has_participant CCO:B0055350 ! PI4KA_HUMAN relationship: has_participant CCO:B0055623 ! GBB2_HUMAN relationship: has_participant CCO:B0058769 ! GBB4_HUMAN relationship: has_participant CCO:B0062773 ! ITM2C_HUMAN relationship: has_participant CCO:B0063067 ! CALX_HUMAN relationship: has_participant CCO:B0063257 ! PDIA6_HUMAN relationship: has_participant CCO:B0063258 ! VPS35_HUMAN [Term] id: CCO:I0007053 name: nmi-stat5a-1 physical interaction comment: Interaction between human Nmi and Stat5a detected by pulldown xref: IntAct:EBI-1190583 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007054 name: tcf7l2-parp1-1 physical interaction comment: PARP1, Ku70 and Ku80 coimmunoprecipitate with FLAG-TCF-4 (TCF7L2) in HEK293 cell lysate xref: IntAct:EBI-1201120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0007055 name: tcf7l2-g22p1 physical interaction comment: Ku70 coimmunoprecipitates with FLAG-TCF-4 constructs containing HMG box in HEK293 cell lysate xref: IntAct:EBI-1201357 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0007056 name: tcf7l2-ctnnb1-7 physical interaction comment: Ku70 and Beta-catenin coimmunoprecipitate with FLAG-TCF-4 in HEK293 cell lysate xref: IntAct:EBI-1201417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0007057 name: cdkn1b-cdk2-2 physical interaction comment: interaction between CDKN1B, CDK2 and CCNA2 demonstrated by SPR xref: IntAct:EBI-1201786 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007058 name: cdkn1b-cdk2-3 direct interaction comment: interaction between CDKN1B and CDK2 demonstrated by SPR xref: IntAct:EBI-1201819 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007059 name: cdkn1b-ccna1-1 direct interaction comment: interaction between CDKN1B and CCNA2 demonstrated by SPR xref: IntAct:EBI-1201829 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007060 name: apbb1-aplp2-1 physical interaction comment: Fe65-APLP2 interaction xref: IntAct:EBI-286397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005374 ! APLP2_HUMAN [Term] id: CCO:I0007061 name: apbb1-app physical interaction comment: FE65-APP xref: IntAct:EBI-286468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007062 name: pard6b-prkci-2 physical interaction comment: interaction detected by CoIP. xref: IntAct:EBI-295452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN [Term] id: CCO:I0007063 name: rac1-pard6b-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-295537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0007064 name: cdc42-pard6b-2 physical interaction comment: Complex detected by CoIP: bait = cdc42, preys = PKC iota, pard6B xref: IntAct:EBI-295543 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0007065 name: pml-daxx-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-295906 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007066 name: daxx-pml-1 physical interaction comment: Interaction detected in vivo by CoIP. xref: IntAct:EBI-295911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007067 name: tubg-mark4-1 physical interaction comment: MARK4 interacts with alpha, beta and gamma-tubulin detected by TAP. xref: IntAct:EBI-351090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001548 ! TBG1_HUMAN relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:I0007068 name: lrpprc-eif3s8-1 physical interaction comment: Interaction detected by comigration. xref: IntAct:EBI-353790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001479 ! ANXA1_HUMAN relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0001691 ! RS4X_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005663 ! TNPO1_HUMAN relationship: has_participant CCO:B0005686 ! HNRPD_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0005725 ! ROA2_HUMAN relationship: has_participant CCO:B0005726 ! RS24_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN relationship: has_participant CCO:B0005729 ! DDX5_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005731 ! ANXA6_HUMAN relationship: has_participant CCO:B0005732 ! HNRH1_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0005734 ! RS8_HUMAN relationship: has_participant CCO:B0005736 ! ANXA2_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0005738 ! VDAC3_HUMAN relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0005741 ! RL18_HUMAN relationship: has_participant CCO:B0005742 ! YBOX1_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN relationship: has_participant CCO:B0005744 ! RS19_HUMAN relationship: has_participant CCO:B0005746 ! RL7_HUMAN relationship: has_participant CCO:B0005748 ! RS13_HUMAN relationship: has_participant CCO:B0005749 ! RS10_HUMAN relationship: has_participant CCO:B0005750 ! RS9_HUMAN relationship: has_participant CCO:B0005751 ! RL22_HUMAN relationship: has_participant CCO:B0005752 ! EF1B_HUMAN relationship: has_participant CCO:B0005753 ! SYFB_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0005755 ! LPPRC_HUMAN relationship: has_participant CCO:B0005756 ! DHRS2_HUMAN relationship: has_participant CCO:B0005758 ! RS7_HUMAN relationship: has_participant CCO:B0005760 ! NEP_HUMAN relationship: has_participant CCO:B0005761 ! RL7A_HUMAN relationship: has_participant CCO:B0005762 ! RLA0_HUMAN relationship: has_participant CCO:B0005763 ! RS18_HUMAN relationship: has_participant CCO:B0005765 ! VDAC1_HUMAN relationship: has_participant CCO:B0005767 ! RS12_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN relationship: has_participant CCO:B0005770 ! RLA1_HUMAN relationship: has_participant CCO:B0005771 ! H2B1C_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN relationship: has_participant CCO:B0005773 ! DDX3X_HUMAN relationship: has_participant CCO:B0005774 ! ROA1_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0005776 ! RSSA_HUMAN relationship: has_participant CCO:B0005777 ! VDAC2_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN relationship: has_participant CCO:B0005779 ! ENOA_HUMAN relationship: has_participant CCO:B0026270 ! EIF3D_HUMAN relationship: has_participant CCO:B0026271 ! EIF3C_HUMAN relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN relationship: has_participant CCO:B0026273 ! EIF3I_HUMAN relationship: has_participant CCO:B0026274 ! EIF3K_HUMAN relationship: has_participant CCO:B0026275 ! EIF3B_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:I0007069 name: abi1-abl1-2 physical interaction xref: IntAct:EBI-375643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:I0007070 name: mdm2-tbp-1 physical interaction comment: the inhibitory domain of MDM2 interacts with both the 34K subunit of TFIIE and TBP. xref: IntAct:EBI-389723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005481 ! TBP_HUMAN [Term] id: CCO:I0007071 name: thrap1-q71f56-1 physical interaction comment: Interaction detected by fractionation off phosphocellulose at P0.5 followed by MudPIT. xref: IntAct:EBI-395095 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005788 ! CD2L6_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005801 ! MD13L_HUMAN [Term] id: CCO:I0007072 name: c20orf20-epc1-2 physical interaction comment: Interaction detected by Anti-FLAG coimmunoprecipitation. xref: IntAct:EBI-399156 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002217 ! ING1_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005916 ! EP400_HUMAN relationship: has_participant CCO:B0005917 ! MO4L1_HUMAN relationship: has_participant CCO:B0049761 ! CA149_HUMAN relationship: has_participant CCO:B0063260 ! RL1D1_HUMAN [Term] id: CCO:I0007073 name: fancd2-brca2-1 physical interaction comment: Interaction between FANCD2 and BRCA2 detected in y2H xref: IntAct:EBI-446104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0002109 ! FACD2_HUMAN [Term] id: CCO:I0007074 name: rhog-elmo1-3 physical interaction comment: Elmo and Dock180 are co-immunoprecipitated with RhoG V12 xref: IntAct:EBI-446727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001704 ! RHOG_HUMAN relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0007076 name: trrap-myc-1 physical interaction comment: TRRAP interacts with c-Myc, as detected by affinity purification. xref: IntAct:EBI-447560 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:I0007077 name: akip-stk6-2 physical interaction comment: immunoprecipitation, prey = human AKIP, bait = human Aurora A xref: IntAct:EBI-448676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0002171 ! AKIP_HUMAN [Term] id: CCO:I0007078 name: bard1-git1 physical interaction xref: IntAct:EBI-473469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:I0007079 name: bard1-hbo1 physical interaction xref: IntAct:EBI-473535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0007080 name: bard1-kiaa1377 physical interaction xref: IntAct:EBI-473546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0007081 name: tada3l-pias4 physical interaction xref: IntAct:EBI-473579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0007082 name: bard1-tcerg1 physical interaction xref: IntAct:EBI-473612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN [Term] id: CCO:I0007083 name: p53-crebbp-2 physical interaction comment: GST-pull down : bait = CBP (CREB binding protein); prey = P53 xref: IntAct:EBI-493319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0007084 name: p53-crebbp-3 physical interaction comment: GST-pull down : bait = P53 ; prey = CBP (CREB binding protein) xref: IntAct:EBI-493328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0007085 name: p53-crebbp-4 physical interaction comment: GST-pull down : bait = CBP (CREB binding protein) CBP3 domain; prey = P53 xref: IntAct:EBI-493344 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0007086 name: p53-crebbp-5 physical interaction comment: GST-pull down : bait = CBP (CREB binding protein); CBP2 domain; prey = P53 xref: IntAct:EBI-493355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0007087 name: pkmyt1-cdc2-2 phosphorylation xref: IntAct:EBI-495361 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:I0007088 name: khdrbs1-fyn-2 physical interaction comment: Interaction between Sam68 and Fyn identified by coimmunoprecipitation xref: IntAct:EBI-518195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0007089 name: khdrbs1-fyn-3 physical interaction comment: Interaction between Sam68 and Fyn identified by coimmunoprecipitation xref: IntAct:EBI-518204 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0007090 name: cdk4-ccnd1-3 physical interaction comment: in vitro co-IP: bait = cyclin D1, prey = cdk4 xref: IntAct:EBI-519398 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:I0007091 name: cdkn1a-ccnd1-1 physical interaction comment: in vitro co-IP: bait = cyclin D1, prey = p21-CIP1 xref: IntAct:EBI-519422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0007092 name: cdkn1b-ccnd1-2 physical interaction comment: in vitro co-IP: bait = cyclin D1, prey = p27-KIP xref: IntAct:EBI-519440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007093 name: srpk1-top2a-1 physical interaction comment: Interaction of SRPK1 and TOP2A emonstrated by copurification xref: IntAct:EBI-539666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002061 ! SRPK1_HUMAN relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:I0007094 name: hcfc1-ogt-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and ogt xref: IntAct:EBI-539854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005806 ! OGT1_HUMAN [Term] id: CCO:I0007095 name: hcfc1-sin3a-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and sin3a xref: IntAct:EBI-540456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:I0007096 name: hcfc1-sin3b-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and sin3b xref: IntAct:EBI-540474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005807 ! SIN3B_HUMAN [Term] id: CCO:I0007097 name: hcfc1-sds3-1 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 and sds3 xref: IntAct:EBI-540503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:I0007098 name: hcfc1-hcfc1-1 physical interaction comment: Immunoblot (co-ip) : overexpressed N-terminus hcfc1 interacts with endogenous hcfc1 c-terminus. xref: IntAct:EBI-540520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN [Term] id: CCO:I0007099 name: mdm2-p53-1 direct interaction comment: Interaction between MDM2 and P53 demonstrated by X-ray crystallography xref: IntAct:EBI-541124 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0007100 name: srpk1-sfrs1-2 physical interaction comment: Interaction between SRPK1 and SFRS1 demonstrated by GST-pulldown xref: IntAct:EBI-593320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002061 ! SRPK1_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:I0007101 name: trx-jab1-2 physical interaction comment: Coimmunoprecipitation reveals interaction between thioredoxin and the COP9 signalosome complex subunit 5 protein xref: IntAct:EBI-594701 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002025 ! CSN5_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:I0007102 name: jab1-trx physical interaction comment: Coimmunoprecipitation reveals interaction between thioredoxin and the COP9 signalosome complex subunit 5 protein xref: IntAct:EBI-594713 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002025 ! CSN5_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:I0007103 name: cul2-cand1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin2 protein and the TIP120A (CAND1) protein xref: IntAct:EBI-595242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001760 ! CUL2_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0007104 name: cul4a-cand1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin4a protein and the TIP120A (CAND1) protein xref: IntAct:EBI-595246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0007105 name: cul1-skp2 physical interaction comment: Coimmunoprecipitaion reveals interaction between the culin1 protein and the S-phase kinase-associated protein 2 xref: IntAct:EBI-595254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:I0007106 name: cul1-cand1-1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein and the TIP120A (CAND1) protein xref: IntAct:EBI-595260 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0007107 name: cand1-cul1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the TIP120A (CAND1) protein and cullin1 protein xref: IntAct:EBI-595265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0007108 name: cand1-cul1-1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the TIP120A (CAND1) protein and cullin1 protein xref: IntAct:EBI-595273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0007109 name: cul1-cand1-2 physical interaction comment: Coimmunoprecipitaion reveals interaction between the cullin1 protein, TIP120A (CAND1) protein and the RING-box protein 1 xref: IntAct:EBI-595277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0007110 name: cul1-skp1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the culin1 protein and the S-phase kinase-associated protein 1 xref: IntAct:EBI-595337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:I0007111 name: cul1-skp1-4 physical interaction comment: Coimmunoprecipitaion reveals interaction between the culin1 protein and the S-phase kinase-associated protein 1 xref: IntAct:EBI-597791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:I0007112 name: cul1-skp2-1 physical interaction comment: Coimmunoprecipitaion reveals interaction between the culin1 protein and the S-phase kinase-associated protein 2 xref: IntAct:EBI-597796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN [Term] id: CCO:I0007113 name: cand1-cul1-4 physical interaction comment: Coimmunoprecipitaion reveals interaction between the TIP120A (CAND1) protein and cullin1 protein xref: IntAct:EBI-597847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0007114 name: cul1-cand1-8 physical interaction comment: Coimmunoprecipitaion reveals interaction between the TIP120A (CAND1) protein and cullin1 protein xref: IntAct:EBI-597852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0007115 name: hcfc1-zbtb17-4 physical interaction comment: GST pull-down to identify which region(s) of zbtb17 (Miz1) are required for interaction with hcfc1. xref: IntAct:EBI-621696 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007116 name: hcfc1-zbtb17-5 physical interaction comment: GST pull-down to identify which region(s) of zbtb17 (Miz1) are required for interaction with hcfc1. xref: IntAct:EBI-621710 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007117 name: hcfc1-zbtb17-6 physical interaction comment: GST pull-down to identify which region(s) of zbtb17 (Miz1) are required for interaction with hcfc1. xref: IntAct:EBI-621722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007118 name: hcfc1-zbtb17-7 physical interaction comment: GST pull-down to identify which region(s) of zbtb17 (Miz1) are required for interaction with hcfc1. xref: IntAct:EBI-621733 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007119 name: hcfc1-zbtb17-8 physical interaction comment: GST pull-down to identify which region(s) of zbtb17 (Miz1) are required for interaction with hcfc1. xref: IntAct:EBI-624075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007120 name: uhrf2-cdk2-4 direct interaction comment: Phosphorylation of UHRF2 (NIRF) by CDK2 xref: IntAct:EBI-625393 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0002054 ! UHRF2_HUMAN [Term] id: CCO:I0007121 name: hcfc1-many-1 physical interaction comment: mass spectrometric analaysis of interaction between hcfc1 and many other proteins xref: IntAct:EBI-629953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005485 ! SP1_HUMAN relationship: has_participant CCO:B0005613 ! SET1A_HUMAN relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0005615 ! WDR5_HUMAN relationship: has_participant CCO:B0005694 ! SDS3_HUMAN relationship: has_participant CCO:B0005806 ! OGT1_HUMAN relationship: has_participant CCO:B0005809 ! RBBP7_HUMAN [Term] id: CCO:I0007122 name: egfr-cbl1-1 direct interaction comment: Interaction between human EGFR and c-Cbl xref: IntAct:EBI-641001 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:I0007123 name: egfr-cbl1-4 direct interaction comment: Interaction between human EGFR and c-Cbl xref: IntAct:EBI-678899 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005611 ! CBL_HUMAN [Term] id: CCO:I0007124 name: actn2-ttn-3 physical interaction comment: Interaction of alpha Actinin-2 and Titin, as detected by affinity techs using Biosensor assay. xref: IntAct:EBI-698598 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0007125 name: actn2-ttn-6 physical interaction comment: Titin, alpha-actinin and F-actin form ternary complexes in vitro. xref: IntAct:EBI-698824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0005810 ! ACTA_HUMAN [Term] id: CCO:I0007126 name: egfr-yes-1 physical interaction comment: Proteomics studies using anti-EGFR affinity chromatography xref: IntAct:EBI-702075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001418 ! DNJA2_HUMAN relationship: has_participant CCO:B0001437 ! BCAR3_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0005204 ! TRI29_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0005463 ! 4F2_HUMAN relationship: has_participant CCO:B0005465 ! YES_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005611 ! CBL_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0005664 ! XPOT_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005732 ! HNRH1_HUMAN relationship: has_participant CCO:B0005771 ! H2B1C_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN relationship: has_participant CCO:B0005811 ! K2C5_HUMAN relationship: has_participant CCO:B0005812 ! FAK1_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN relationship: has_participant CCO:B0005814 ! HNRPF_HUMAN relationship: has_participant CCO:B0005815 ! EFNB1_HUMAN relationship: has_participant CCO:B0005816 ! ATX10_HUMAN relationship: has_participant CCO:B0005817 ! K1C14_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN relationship: has_participant CCO:B0005819 ! CBLB_HUMAN relationship: has_participant CCO:B0005820 ! PEX19_HUMAN relationship: has_participant CCO:B0005821 ! K2C6A_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0005823 ! K2C1_HUMAN relationship: has_participant CCO:B0005824 ! CTNA1_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN relationship: has_participant CCO:B0005826 ! PKP2_HUMAN relationship: has_participant CCO:B0005827 ! ATPB_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0005829 ! CKAP4_HUMAN relationship: has_participant CCO:B0005830 ! FHL2_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0005832 ! EPHA2_HUMAN relationship: has_participant CCO:B0005833 ! EPHB4_HUMAN relationship: has_participant CCO:B0005834 ! EI2BG_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN relationship: has_participant CCO:B0005836 ! ACK1_HUMAN relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0005838 ! H14_HUMAN relationship: has_participant CCO:B0005839 ! CTND1_HUMAN relationship: has_participant CCO:B0005840 ! AT2A2_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0005844 ! K1C17_HUMAN relationship: has_participant CCO:B0005845 ! LRC59_HUMAN relationship: has_participant CCO:B0005846 ! FAK2_HUMAN relationship: has_participant CCO:B0005847 ! MPCP_HUMAN [Term] id: CCO:I0007127 name: wrn-rad52-6 physical interaction comment: In vivo Co-IP: bait= WRN, prey= RAD52 xref: IntAct:EBI-706526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007128 name: wrn-rad52-7 physical interaction comment: In vivo Co-IP: bait= RAD52, prey= WRN xref: IntAct:EBI-706533 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007129 name: bbc3-bcl2-5 direct interaction comment: Interaction of BBC3 with BCL-2 by coimmunoprecipitation xref: IntAct:EBI-709079 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN [Term] id: CCO:I0007130 name: bbc3-bcl2-6 direct interaction comment: Interaction of BBC3 with BCL-2 by coimmunoprecipitation xref: IntAct:EBI-709088 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN [Term] id: CCO:I0007131 name: terf2ip-rad50 physical interaction comment: Coimmunoprecipitaion reveals interaction between RAP1, RAD50, Mre11, Ku86, TRF2, HSP70 and TINF2 proteins xref: IntAct:EBI-764884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001788 ! MDC1_HUMAN relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0006245 ! TINF2_HUMAN [Term] id: CCO:I0007132 name: bcap31-bcl2 physical interaction comment: Interaction of BCL-2 with p28Bap31 identified by co-immunoprecipitation xref: IntAct:EBI-78097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005676 ! BAP31_HUMAN [Term] id: CCO:I0007133 name: brca2-shfdg1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-79835 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0005586 ! DSS1_HUMAN [Term] id: CCO:I0007134 name: hdac3-mbd1-1 physical interaction comment: Interaction between MBD1 and HDAC3 determined by pull down. xref: IntAct:EBI-867358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001376 ! HDAC3_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0007135 name: dlg1-kif13b-3 physical interaction comment: Co-IP: bait= GAKIN,prey = hDlg (SAP97) xref: IntAct:EBI-874729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001736 ! DLG1_HUMAN relationship: has_participant CCO:B0005849 ! KI13B_HUMAN [Term] id: CCO:I0007136 name: gli3-sufu-1 direct interaction comment: Interaction between GLI3 and SUFU demonstrated by GST pulldown xref: IntAct:EBI-875115 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN [Term] id: CCO:I0007137 name: sufu-sufu-1 direct interaction comment: Homodimerisation of SUFU demonstrated by GST pulldown xref: IntAct:EBI-875131 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002232 ! SUFU_HUMAN [Term] id: CCO:I0007138 name: calm physical interaction comment: Affinity chromotography reveals Calmodulin (CALM) interacting proteins xref: IntAct:EBI-911456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005851 ! DIRA2_HUMAN [Term] id: CCO:I0007139 name: tcf4-daxx physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the TCF-4 protein and Daxx protein xref: IntAct:EBI-924794 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007140 name: tcf4-daxx-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the TCF-4 protein and Daxx protein xref: IntAct:EBI-924818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007141 name: daxx-tcf4 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the Daxx protein and TCF-4 protein xref: IntAct:EBI-924832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007142 name: tcf4-ctnnb1 physical interaction comment: Coimmunoprecipitaion reveals interaction between Tcf4 and CTNNB1 xref: IntAct:EBI-924960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007143 name: erbb3-pa2g4-1 physical interaction xref: IntAct:EBI-931862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN [Term] id: CCO:I0007144 name: pa2g4-ar-1 physical interaction xref: IntAct:EBI-931867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:I0007145 name: pa2g4-ncl-top1-1 physical interaction xref: IntAct:EBI-932569 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0005587 ! TOP1_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0005741 ! RL18_HUMAN relationship: has_participant CCO:B0005762 ! RLA0_HUMAN relationship: has_participant CCO:B0005853 ! RL28_HUMAN relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0005855 ! RL12_HUMAN relationship: has_participant CCO:B0005856 ! RL24_HUMAN relationship: has_participant CCO:B0005857 ! RL15_HUMAN relationship: has_participant CCO:B0005858 ! RL11_HUMAN relationship: has_participant CCO:B0005859 ! RL27_HUMAN relationship: has_participant CCO:B0005860 ! RL8_HUMAN relationship: has_participant CCO:B0005861 ! RL4_HUMAN relationship: has_participant CCO:B0005862 ! RL21_HUMAN relationship: has_participant CCO:B0005863 ! H11_HUMAN relationship: has_participant CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:I0007146 name: p300-tfap2a-1 physical interaction comment: Interaction between human p300 and TFAP2A detected by coIP xref: IntAct:EBI-937720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0007147 name: p300-cited2-1 physical interaction comment: Interaction between human p300 and CITED2 detected by coIP xref: IntAct:EBI-937728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN [Term] id: CCO:I0007148 name: s100b-s100a11-s100a6 colocalization comment: Colocalisation of human S100B, S100A11 and S100A6 detected by confocal microscopy xref: IntAct:EBI-959993 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:I0007149 name: dusp1-skp2-3 physical interaction comment: Interaction between DUSP1 and SKP2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-975649 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001566 ! DUS1_HUMAN relationship: has_participant CCO:B0001628 ! UB2R1_HUMAN relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:I0007150 name: cbp-atf3 physical interaction xref: IntAct:EBI-981234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN [Term] id: CCO:I0007151 name: brca2-rad51-8 physical interaction comment: Interaction between BRCA2 and RAD51 determined by GST-pulldown xref: IntAct:EBI-987332 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007152 name: daxx-stat3-3 colocalization xref: IntAct:EBI-991438 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:I0007153 name: ranbp3-ran-1 physical interaction xref: IntAct:EBI-992712 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:I0007154 name: ranbp3-rcc1-1 physical interaction xref: IntAct:EBI-992738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:I0007155 name: rcc1-xpo1-1 physical interaction xref: IntAct:EBI-992749 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN [Term] id: CCO:I0007156 name: kntc2-cdca1-4 physical interaction xref: IntAct:EBI-1000008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN [Term] id: CCO:I0007157 name: kntc2_zwint_2 physical interaction comment: pull down: bait=kntc2, prey=zwint xref: IntAct:EBI-1001499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0007158 name: zwint_kntc2_2 physical interaction comment: pull down: bait=zwint, preys=kntc2, zw10 xref: IntAct:EBI-1001508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0007159 name: kntc2_zwint_3 physical interaction comment: pull down: bait=kntc2, preys=zwint, zw10 xref: IntAct:EBI-1001525 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0007160 name: zw10_kntc2_1 physical interaction comment: pull down: bait=zw10, preys=kntc2, zwint xref: IntAct:EBI-1001549 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0007161 name: zwint_kntc2_3 physical interaction comment: coIP: bait=zwint, prey=kntc2 xref: IntAct:EBI-1001631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0007162 name: zw10_kntc2_2 physical interaction comment: coIP: bait=zw10, prey=kntc2 xref: IntAct:EBI-1001639 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0007163 name: raf1-rap1a-2 direct interaction comment: Human rap1a, residues 1-167, double mutant (e30d,k31e) complexed with gppnhp and the ras-binding-domain of human c-raf1, residues 51-131 xref: IntAct:EBI-1026154 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0007164 name: fgf2-fgfr1-2 direct interaction comment: Crystal structure of a ternary fgf2-fgfr1-heparin complex xref: IntAct:EBI-1030022 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0005868 ! FGFR1_HUMAN [Term] id: CCO:I0007165 name: ube2n-ube2v2-1 direct interaction comment: Crystal structure of hmms2-hubc13 xref: IntAct:EBI-1031621 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001813 ! UB2V2_HUMAN relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN [Term] id: CCO:I0007166 name: tp53-tp53bp1-1 direct interaction comment: Crystal structure of the 53bp1 brct region complexed to tumor suppressor p53 xref: IntAct:EBI-1033085 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:I0007167 name: egfr-tgfa-1 direct interaction comment: Crystal structure of human epidermal growth factor receptor (residues 1-501) in complex with tgf-alpha xref: IntAct:EBI-1034394 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005870 ! TGFA_HUMAN [Term] id: CCO:I0007168 name: f2-f2-1 physical interaction comment: 2.5a crystal structure of the antithrombin-thrombin-heparin ternary complex xref: IntAct:EBI-1039853 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0005871 ! ANT3_HUMAN [Term] id: CCO:I0007169 name: kntc2-spbc24-4 physical interaction xref: IntAct:EBI-1101410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0007170 name: abl2-rin1-4 physical interaction comment: Interaction between Abl2, Hras and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN relationship: has_participant CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:I0007171 name: abl1-rin1-4 phosphorylation comment: Phosphorylation of Rin1 by Abl1 xref: IntAct:EBI-1103017 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0007172 name: tacc1-yeats4-4 colocalization xref: IntAct:EBI-1151873 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN [Term] id: CCO:I0007173 name: dj_1-ubc9 physical interaction xref: IntAct:EBI-1164415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005443 ! PARK7_HUMAN [Term] id: CCO:I0007174 name: dj_1-daxx-1 physical interaction xref: IntAct:EBI-1164435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005443 ! PARK7_HUMAN [Term] id: CCO:I0007175 name: hif1a-os9-4 direct interaction comment: GST-HIF-1-alpha pulls down OS-9 and VHL xref: IntAct:EBI-1175463 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0007176 name: hif1a-vhl physical interaction comment: GST-HIF-1 alpha pulls down VHL xref: IntAct:EBI-1175529 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:I0007177 name: cspg6-rad21 physical interaction xref: IntAct:EBI-1175616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN [Term] id: CCO:I0007178 name: chek2-aatf-1 physical interaction comment: Che-1 coimmunoprecipitates with Chk2 xref: IntAct:EBI-1180890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0007179 name: prkaa1-aakg1-1 physical interaction comment: Binding partners of PRKAA1 identified by mass spectrometry xref: IntAct:EBI-1181432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0005872 ! AAPK1_HUMAN relationship: has_participant CCO:B0016329 ! AAKG1_HUMAN relationship: has_participant CCO:B0054517 ! AAKB2_HUMAN relationship: has_participant CCO:B0059353 ! AAKB1_HUMAN [Term] id: CCO:I0007180 name: snf1lk-ywhaz-1 physical interaction comment: Binding partners of SNF1LK (SIK) identified by mass spectrometry xref: IntAct:EBI-1181636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN [Term] id: CCO:I0007181 name: snf1l2-2aab-1 physical interaction comment: Binding partners of SNF1L2 (QIK) identified by mass spectrometry xref: IntAct:EBI-1181690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0005517 ! 2AAB_HUMAN relationship: has_participant CCO:B0005873 ! SN1L2_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN relationship: has_participant CCO:B0026114 ! 2ABA_HUMAN [Term] id: CCO:I0007182 name: nuak2-cdc37-1 physical interaction comment: Binding partners of NUAK2 identified by mass spectrometry xref: IntAct:EBI-1181741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005874 ! NUAK2_HUMAN [Term] id: CCO:I0007183 name: snf1lk-ywhaz-2 direct interaction comment: Interaction between 14-3-3Z and SNF1LK (SIK)identified by pulldown xref: IntAct:EBI-1181931 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0007184 name: stat5b-nmi-3 physical interaction comment: Interaction between human Stat5b and Nmi detected by coIP xref: IntAct:EBI-1186206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007185 name: cbp-stat5a-1 physical interaction comment: Interaction between human CBP and Stat5a detected by coIP xref: IntAct:EBI-1186218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007186 name: cbp-stat5b-1 physical interaction comment: Interaction between human CBP and Stat5b detected by coIP xref: IntAct:EBI-1186238 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007187 name: myc-snip1-3 physical interaction comment: Endogenous SNIP1 complex formation with endogenous c-Myc varies with cell cycle progression xref: IntAct:EBI-1190137 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0007188 name: myc-skp2-1 physical interaction comment: Endogenous Skp2 complex formation with endogenous c-Myc varies with cell cycle progression xref: IntAct:EBI-1190143 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:I0007189 name: hdac1-brms1 physical interaction comment: HDAC1 coimmunoprecipitates BRMS1 xref: IntAct:EBI-1200310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0007190 name: hdac2-brms1 physical interaction comment: HDAC2 coimmunoprecipitates BRMS1 xref: IntAct:EBI-1200318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0007191 name: hdac3-brms1 physical interaction comment: HDAC3 coimmunoprecipitates BRMS1 xref: IntAct:EBI-1200326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001376 ! HDAC3_HUMAN relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN [Term] id: CCO:I0007192 name: hdac4-brms1 physical interaction comment: HDAC4 coimmunoprecipitates BRMS1 xref: IntAct:EBI-1200336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN [Term] id: CCO:I0007193 name: hdac5-brms1 physical interaction comment: HDAC5 coimmunoprecipitates BRMS1 xref: IntAct:EBI-1200344 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0002244 ! HDAC5_HUMAN [Term] id: CCO:I0007194 name: hdac6-brms1 physical interaction comment: HDAC6 coimmunoprecipitates BRMS1 xref: IntAct:EBI-1200352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN [Term] id: CCO:I0007195 name: lck-ptprc physical interaction comment: Lck-CD45 demonstrated in vitro xref: IntAct:EBI-1356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001499 ! CD45_HUMAN [Term] id: CCO:I0007196 name: krt18-shc1-1 colocalization comment: Colocalization by confocal microscopy of fluroscence labeled proteins. xref: IntAct:EBI-298042 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN [Term] id: CCO:I0007197 name: egfr-h3fa-1 colocalization comment: Colocalization indicated by confocal microscopy of fluroscently tagged proteins. xref: IntAct:EBI-298046 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005221 ! H31_HUMAN [Term] id: CCO:I0007198 name: egfr-cd59-1 direct interaction comment: Interaction detected by FRET. xref: IntAct:EBI-298103 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005875 ! CD59_HUMAN [Term] id: CCO:I0007199 name: pard3-pard6b-2 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-306756 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN [Term] id: CCO:I0007200 name: pard3-pard6a-3 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-306767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN [Term] id: CCO:I0007201 name: stk11-mo25-1 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-306911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0005876 ! CAB39_HUMAN [Term] id: CCO:I0007202 name: pard3-pard6a-2 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-306996 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN [Term] id: CCO:I0007203 name: pard6a-prkci-2 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-306999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007204 name: pard6a-par6b-1 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307005 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN [Term] id: CCO:I0007205 name: pard6a-cdc42-5 physical interaction comment: CoIP: bait = pard6a, prey = cdc42 xref: IntAct:EBI-307047 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0007206 name: prkci-pard6a-1 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007207 name: prkci-pard6b-2 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007208 name: als2cr2-stk11-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0002119 ! STRAB_HUMAN [Term] id: CCO:I0007209 name: mo25-als2cr2-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307245 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002119 ! STRAB_HUMAN relationship: has_participant CCO:B0005876 ! CAB39_HUMAN [Term] id: CCO:I0007210 name: pard6a-mark4-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307250 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005344 ! MARK4_HUMAN [Term] id: CCO:I0007211 name: prkci-pard3-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007212 name: ywhaz-pard3-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-347038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0007213 name: pard6a-ywhah-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-349731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0007214 name: pard6a-ywhaz-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-349738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0007215 name: pard6b-ywhah-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-349750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0007216 name: pard6b-ywhaz-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-349754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0007217 name: stk11-mark4-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0005344 ! MARK4_HUMAN [Term] id: CCO:I0007218 name: pard3-ywhaz-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0007219 name: ywhah-pard3-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354820 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0007220 name: pard3-ywhah-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0007221 name: pard3-prkci-2 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007222 name: mo25-stk11-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0005876 ! CAB39_HUMAN [Term] id: CCO:I0007223 name: stk11-als2cr2-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354843 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0002119 ! STRAB_HUMAN [Term] id: CCO:I0007224 name: cdc42-pard6a-2 physical interaction comment: CoIP: bait = human cdc42, prey = human pard6a xref: IntAct:EBI-360124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0007225 name: pard6b-cdc42-6 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360129 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0007226 name: cdc42-pard6b-3 physical interaction comment: CoIP: bait = human cdc42, prey = par6B xref: IntAct:EBI-360134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0007227 name: pard6b-pnma1-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005877 ! PNMA1_HUMAN [Term] id: CCO:I0007228 name: pnma1-pard6b-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005877 ! PNMA1_HUMAN [Term] id: CCO:I0007229 name: pard6b-prkci-3 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007230 name: pard6b-pard3-2 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0005877 ! PNMA1_HUMAN [Term] id: CCO:I0007231 name: pard3-pnma1-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005877 ! PNMA1_HUMAN [Term] id: CCO:I0007232 name: pnma1-pard3-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360171 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0005877 ! PNMA1_HUMAN [Term] id: CCO:I0007233 name: rad51-tp53-1 physical interaction comment: Interaction of p53 and the human Rad51 protein detected by Co-IP. xref: IntAct:EBI-367003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007234 name: rad51-tp53-2 physical interaction comment: Interaction of p53 with the human Rad51 protein detected by CO-IP xref: IntAct:EBI-367053 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007235 name: nek1-fez2-2 physical interaction comment: Interaction between NEK1 requlatory domain and ZBRK1 identified by Y2H xref: IntAct:EBI-396634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005394 ! FEZ2_HUMAN [Term] id: CCO:I0007236 name: lats1-zyx-6 colocalization comment: Interaction betwen human LATS1 and ZYX demonstrate by colocalization studies xref: IntAct:EBI-444294 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007237 name: lats1-limk1-5 colocalization comment: Colocalization of human LATS1 and LIMK1 xref: IntAct:EBI-444493 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:I0007238 name: rhog-elmo1-2 physical interaction comment: RhoG V12 binds to Elmo in GST pull-down assay xref: IntAct:EBI-446615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001704 ! RHOG_HUMAN relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN [Term] id: CCO:I0007239 name: cdt1-cdc6-1 physical interaction comment: Interaction of CDT1 and CDC6 identified by GST pull-down xref: IntAct:EBI-457031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:I0007240 name: cdt1-cdc6-2 physical interaction comment: Interaction of CDT1 and CDC6 identified by GST pull-down xref: IntAct:EBI-457078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:I0007241 name: hd-p53-2 physical interaction comment: GST-pull down : bait = huntingtin poly(Q) region ; prey = P53 xref: IntAct:EBI-492998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0007242 name: p53-crebbp-1 physical interaction comment: GST-pull down : bait = P53 ; prey = CBP (CREB binding protein) xref: IntAct:EBI-493156 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN [Term] id: CCO:I0007243 name: p53-sin3a-1 physical interaction comment: GST-pull down : bait = P53 ; prey = Sin3a xref: IntAct:EBI-493181 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:I0007244 name: pkmyt1-ccnb1-1 physical interaction xref: IntAct:EBI-495328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:I0007245 name: ccnb1-pkmyt1-1 physical interaction xref: IntAct:EBI-495391 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN [Term] id: CCO:I0007246 name: tnf-tnfrsf1a-1 direct interaction comment: Purification by immunoaffinity after cross-linking of TNF-alpha / TNF-alpha Receptor xref: IntAct:EBI-514406 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0007247 name: cdk2-ccne1-2 physical interaction comment: Co-IP : bait=cdk2, prey = cyclin E1 xref: IntAct:EBI-519746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007248 name: cdk4-ccnd1-6 physical interaction comment: Co-IP : bait=cdk4, prey = cyclin D1 xref: IntAct:EBI-519761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:I0007249 name: rent1-stau-6 physical interaction xref: IntAct:EBI-536644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005434 ! REN3B_HUMAN relationship: has_participant CCO:B0005435 ! RENT2_HUMAN [Term] id: CCO:I0007250 name: srpk1-top2a-2 physical interaction comment: Interaction of SRPK1 and TOP2A emonstrated by copurification xref: IntAct:EBI-539669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002061 ! SRPK1_HUMAN relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:I0007251 name: hcfc1-sin3a-2 physical interaction comment: Y2H of interaction between specific regions of hcfc1 and sin3a xref: IntAct:EBI-540758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:I0007252 name: trx-jab1-5 physical interaction comment: Pulldown analysis reveals interaction between thioredoxin and the COP9 signalosome complex subunit 5 protein xref: IntAct:EBI-594727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002025 ! CSN5_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:I0007253 name: trx-jab1-cdn1b physical interaction comment: Pulldown analysis reveals interaction between the cyclin-dependent kinase inhibitor 1B , thioredoxin and the COP9 signalosome complex subunit 5 protein xref: IntAct:EBI-594810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0002025 ! CSN5_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:I0007254 name: cand1-cul1-2 physical interaction comment: GST pulldown reveals interaction between the TIP120A (CAND1) protein and cullin1 protein xref: IntAct:EBI-597737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN [Term] id: CCO:I0007255 name: gpsm2-numa1-3 physical interaction xref: IntAct:EBI-618880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0007256 name: huew1-cdkn2a-1 physical interaction comment: coIP: bait = arf-bp1/mule, prey = p14arf xref: IntAct:EBI-626122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:I0007257 name: cdkn2a-huew1-3 physical interaction comment: coIP: bait = p14arf, prey = arf-bp1/mule xref: IntAct:EBI-626129 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:I0007258 name: smarcb1-arid2-1 physical interaction comment: coIP: bait = flag-hsnf5; prey = baf200 xref: IntAct:EBI-637847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0007259 name: arid2-pb1-1 physical interaction comment: coIP: bait = flag-baf200, preys = baf180, brg1, baf170, baf155, baf57, hsnf5 xref: IntAct:EBI-637916 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0007260 name: brg1-baf250a-1 physical interaction comment: coIP: bait = brg1, preys = baf250a, baf170, baf155, baf60a, baf53, snf5, actin xref: IntAct:EBI-637974 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0007261 name: hcfc1-gabp2-3 physical interaction comment: GST pull-down of interaction between hcfc1 and gabp2. xref: IntAct:EBI-638915 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0040683 ! GABP1_HUMAN [Term] id: CCO:I0007262 name: hcfc1-gabpa-1 physical interaction comment: GST pull-down of interaction between hcfc1 and gabpa. xref: IntAct:EBI-638943 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005878 ! GABPA_HUMAN [Term] id: CCO:I0007263 name: hcfc1-gabp2-4 direct interaction comment: GST pull-down of interaction between hcfc1 and gabp2. xref: IntAct:EBI-638955 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005878 ! GABPA_HUMAN relationship: has_participant CCO:B0040683 ! GABP1_HUMAN [Term] id: CCO:I0007264 name: hcfc1-creb3-3 direct interaction comment: Immunoblot (Co-ip) showing interaction between hcfc1 and creb3 and between hcfc1 and zf xref: IntAct:EBI-640523 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0007265 name: hcfc1-zf-6 direct interaction comment: Immunoblot (Co-ip) showing interaction between hcfc1 and creb3 and between hcfc1 and zf xref: IntAct:EBI-641398 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0007266 name: hcfc1-creb3-4 direct interaction comment: Immunoblot (Co-ip) showing interaction between hcfc1 and creb3 xref: IntAct:EBI-641418 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN [Term] id: CCO:I0007267 name: hcfc1-zf-7 direct interaction comment: Immunoblot (Co-ip) showing interaction between hcfc1 and zf xref: IntAct:EBI-641438 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0007268 name: nek1-fez1-3 physical interaction comment: Interaction between NEK1 requlatory domain and ZBRK1 identified by Y2H xref: IntAct:EBI-695904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN [Term] id: CCO:I0007269 name: nek1-ywhah-1 physical interaction comment: Interaction between NEK1 requlatory domain and YWHAHidentified by Y2H xref: IntAct:EBI-695925 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0007270 name: nek1-xh2-1 physical interaction comment: Interaction between NEK1 requlatory domain and XH2 identified by Y2H xref: IntAct:EBI-695931 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:I0007271 name: nek1-mre11-1 physical interaction comment: Interaction between NEK1 requlatory domain and MRE11 identified by Y2H xref: IntAct:EBI-695941 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001641 ! MRE11_HUMAN relationship: has_participant CCO:B0002055 ! NEK1_HUMAN [Term] id: CCO:I0007272 name: nek1-tp53bp1-1 physical interaction comment: Interaction between NEK1 requlatory domain and TP53BP1 identified by Y2H xref: IntAct:EBI-695947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005412 ! TP53B_HUMAN [Term] id: CCO:I0007273 name: nek1-kif3a physical interaction comment: Interaction between NEK1 requlatory domain and KIF3A identified by Y2H xref: IntAct:EBI-695956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005880 ! KIF3A_HUMAN [Term] id: CCO:I0007274 name: nek1-ppp2r5d-1 physical interaction comment: Interaction between NEK1 requlatory domain and PPP2R5D identified by Y2H xref: IntAct:EBI-695966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN [Term] id: CCO:I0007275 name: nek1-tsc2-1 physical interaction comment: Interaction between NEK1 requlatory domain and TSC2 identified by Y2H xref: IntAct:EBI-695974 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0002055 ! NEK1_HUMAN [Term] id: CCO:I0007276 name: nek1-ctnnal1-1 physical interaction comment: Interaction between NEK1 requlatory domain and CTNNAL1 identified by Y2H xref: IntAct:EBI-695982 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005881 ! CTNL1_HUMAN [Term] id: CCO:I0007277 name: nek1-tsc2-2 physical interaction comment: Interaction between NEK1 kinase domain and TSC2 identified by Y2H xref: IntAct:EBI-696008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0002055 ! NEK1_HUMAN [Term] id: CCO:I0007278 name: nek1-tsc2-3 physical interaction comment: Interaction between NEK1 kinase domain and TSC2 identified by Y2H xref: IntAct:EBI-696015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN [Term] id: CCO:I0007279 name: nek1-nek1-1 physical interaction comment: Homodimerization of NEK1 identified by Y2H xref: IntAct:EBI-696022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002055 ! NEK1_HUMAN [Term] id: CCO:I0007280 name: raf1-hras-3 physical interaction comment: Interaction between c-Raf and Ras detected by yeast two hybrid. xref: IntAct:EBI-696110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0007281 name: wrn-rpa70-1 physical interaction comment: Y2H: bait = RPA70, prey = WRN xref: IntAct:EBI-707130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007282 name: rpa1-rpa2-2 physical interaction comment: Y2H: bait = RPA32, prey= RPA70 xref: IntAct:EBI-707143 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN [Term] id: CCO:I0007283 name: blm-terf2-1 physical interaction comment: In vivo Co-IP: bait= BLM, prey =TRF2 xref: IntAct:EBI-710854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0007284 name: app-tp53bp2-1 physical interaction comment: APP- TP53BP2 xref: IntAct:EBI-77660 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007285 name: app-tp53bp2-3 physical interaction comment: APP-TP53BP2 pulldown xref: IntAct:EBI-77665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007286 name: adam9-mad2l2-1 physical interaction xref: IntAct:EBI-77923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN [Term] id: CCO:I0007287 name: dnmt3b-ube2i-1 physical interaction xref: IntAct:EBI-80228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN [Term] id: CCO:I0007288 name: fshr-ywhaq-2 physical interaction comment: Y2H: bait= FSHR intracellular loop 2, prey = 14-3-3 tau isoform xref: IntAct:EBI-848290 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005506 ! FSHR_HUMAN [Term] id: CCO:I0007289 name: pold1-pold2-4 physical interaction comment: Assembly of DNA polymerase delta identifed by column chromotography xref: IntAct:EBI-865032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:I0007290 name: pold1-pold2-5 physical interaction comment: Assembly of DNA polymerase delta subunits 1 and 2 identifed by column chromotography xref: IntAct:EBI-865046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN [Term] id: CCO:I0007291 name: pole3-pole4-6 physical interaction comment: Interaction between POLE3 and POLE4 identified by coimmunoprecipitation xref: IntAct:EBI-867144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN relationship: has_participant CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:I0007292 name: tle1-aml2-1 physical interaction comment: Interaction between human TLE1 and AML2 detected by beta galactosidase xref: IntAct:EBI-926094 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0007293 name: disc1-atf5-1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-929093 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0007294 name: pa2g4-ncl-1 physical interaction xref: IntAct:EBI-932860 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:I0007295 name: fgfbp1-fgf2-1 direct interaction comment: Interaction between FGFBP1 and FGF2 identified by phage display xref: IntAct:EBI-977443 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0005646 ! FGFP1_HUMAN [Term] id: CCO:I0007296 name: fgfbp1-fgf2-2 direct interaction comment: Interaction between FGFBP1 and FGF2 identified by phage display xref: IntAct:EBI-977556 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0005646 ! FGFP1_HUMAN [Term] id: CCO:I0007297 name: sgol1-ppp2r5a-2 colocalization xref: IntAct:EBI-989200 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0007298 name: rcc1-ranbp3-1 physical interaction xref: IntAct:EBI-992766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0005866 ! RANB3_HUMAN [Term] id: CCO:I0007299 name: daxx-mdm2 colocalization xref: IntAct:EBI-992918 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007300 name: daz1-boll-1 physical interaction xref: IntAct:EBI-998221 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001972 ! BOLL_HUMAN relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN [Term] id: CCO:I0007301 name: kntc2-spbc24-1 physical interaction xref: IntAct:EBI-999950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0007302 name: spbc24-spbc25-3 physical interaction xref: IntAct:EBI-999976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0007303 name: kntc2-cdca1-3 physical interaction xref: IntAct:EBI-999994 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN [Term] id: CCO:I0007304 name: erbb2-egfr-2 physical interaction xref: IntAct:EBI-1000739 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0007305 name: erbb2-egfr-3 physical interaction xref: IntAct:EBI-1000759 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0007306 name: smc1-mcm7-6 physical interaction comment: Interaction between human Smc1 and MCM7 detected by coIP xref: IntAct:EBI-1004776 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0007307 name: smc1-rfc1-1 physical interaction comment: Interaction between human Smc1 and RFC1 detected by coIP xref: IntAct:EBI-1004786 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0005887 ! RFC1_HUMAN [Term] id: CCO:I0007308 name: smc1-dpola-1 physical interaction comment: Interaction between human Smc1 and DNA polymerase alpha detected by coIP xref: IntAct:EBI-1004802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0007309 name: rb1-hdac1 physical interaction xref: IntAct:EBI-1025609 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0007310 name: ran-tnpo1-1 direct interaction comment: Structure of the karyopherin beta2-ran gppnhp nuclear transport complex xref: IntAct:EBI-1027757 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005663 ! TNPO1_HUMAN [Term] id: CCO:I0007312 name: rps27a-tsg101-1 direct interaction comment: Tsg101(uev) domain in complex with ubiquitin xref: IntAct:EBI-1038470 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0007313 name: zo_1-actn4-7 colocalization xref: IntAct:EBI-1103480 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:I0007314 name: tacc1-ckap5 physical interaction xref: IntAct:EBI-1151162 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001772 ! CKAP5_HUMAN [Term] id: CCO:I0007315 name: tacc1-yeats4 physical interaction xref: IntAct:EBI-1151252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN [Term] id: CCO:I0007316 name: bhlbh2-ube2i physical interaction xref: IntAct:EBI-1164831 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN [Term] id: CCO:I0007317 name: tap1-calr direct interaction xref: IntAct:EBI-1168126 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001563 ! CALR_HUMAN relationship: has_participant CCO:B0005889 ! TAP1_HUMAN [Term] id: CCO:I0007318 name: cdca1-kntc2 physical interaction comment: Copurification of the two subunits of the human Ndc80 complex: Hec1/hNdc80 and hNuf2 xref: IntAct:EBI-1176296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN [Term] id: CCO:I0007320 name: parp1-tcf7l2-1 physical interaction comment: TCF-4 (TCF7L2), Ku70 and Ku80 coimmunoprecipitate with PARP1 in HEK293 cell lysate xref: IntAct:EBI-1201141 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0007321 name: g22p1-parp1 physical interaction comment: TCF-4 (TCF7L2), PARP1 and Ku80 coimmunoprecipitate with Ku70 in HEK293 cell lysate xref: IntAct:EBI-1201176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0007322 name: mapkapk5-tp53 phosphorylation comment: Human HA-PRAK phosphorylates human p53 in vitro xref: IntAct:EBI-1201485 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005891 ! MAPK5_HUMAN [Term] id: CCO:I0007323 name: cdkn1b-cdk2-4 physical interaction comment: interaction between CDKN1B, CDK2 and CCNA2 demonstrated by NMR xref: IntAct:EBI-1201881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007324 name: mapkapk5-tp53-1 phosphorylation comment: Human His-PRAK phosphorylates human p53 in vitro xref: IntAct:EBI-1202077 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005891 ! MAPK5_HUMAN [Term] id: CCO:I0007325 name: mapk11-tp53-1 phosphorylation comment: Human p38 isolated from BJ cells phosphorylates p53 in vitro xref: IntAct:EBI-1206378 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005892 ! MK11_HUMAN [Term] id: CCO:I0007326 name: ncoa6-rara-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:I0007327 name: ncoa6-rara-2 physical interaction comment: Regions of hNCOA6 important for interactions determined by Y2H. xref: IntAct:EBI-286389 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:I0007328 name: eif4gii-eif4aii physical interaction comment: A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery xref: IntAct:EBI-296538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001699 ! IF4G2_HUMAN relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN [Term] id: CCO:I0007329 name: hck-dnm2-1 physical interaction comment: Interaction between HCK and DNM2 detected by GST pull down xref: IntAct:EBI-346570 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0007330 name: hck-p62-1 physical interaction comment: Interaction between HCK and P62 detected by GST pull down xref: IntAct:EBI-346693 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0007331 name: hck-cd2ap-1 physical interaction comment: Interaction between HCK and CD2AP detected by GST pull down xref: IntAct:EBI-346699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0007332 name: pbx2-mcrs1 physical interaction xref: IntAct:EBI-348664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:I0007333 name: pbx2-p22 physical interaction xref: IntAct:EBI-348688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001440 ! DCTN3_HUMAN relationship: has_participant CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:I0007334 name: stk19-pole physical interaction xref: IntAct:EBI-348706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0005896 ! STK19_HUMAN [Term] id: CCO:I0007335 name: bat5-ifitm1 physical interaction xref: IntAct:EBI-348757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001517 ! IFM1_HUMAN relationship: has_participant CCO:B0005571 ! BAT5_HUMAN [Term] id: CCO:I0007336 name: csnk2b-csnk2a2 physical interaction xref: IntAct:EBI-348796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001537 ! CSK22_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:I0007337 name: bat2-mad2l2 physical interaction xref: IntAct:EBI-348871 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:I0007338 name: bat1-hipk2 physical interaction xref: IntAct:EBI-348913 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002130 ! HIPK2_HUMAN relationship: has_participant CCO:B0005899 ! UAP56_HUMAN [Term] id: CCO:I0007339 name: mdm2-mdm4-2 physical interaction comment: MDMX and MDM2 associate in vitro. xref: IntAct:EBI-399552 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0007340 name: mdm2-mdm4-3 physical interaction comment: MDMX and MDM2 associate in vitro. xref: IntAct:EBI-399556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0007341 name: krt8-krt18 physical interaction comment: keratin and keratin 18 association measured by antibody affinity xref: IntAct:EBI-445615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0005900 ! K2C8_HUMAN [Term] id: CCO:I0007342 name: h2afx-nbs1-4 physical interaction xref: IntAct:EBI-495255 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0007343 name: bcl_xl-bax physical interaction comment: The Bcl_xl protein interacts with the BAX protein xref: IntAct:EBI-516576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0007344 name: cam-cd95 physical interaction comment: The calmodulin protein interacts with the CD95(Fas) protein xref: IntAct:EBI-518165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN [Term] id: CCO:I0007345 name: lepr-jak2-1 physical interaction comment: Interaction of the Leptin receptor with JAK2 and JAK3 identified by coimmunoprecipitation xref: IntAct:EBI-518671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0005612 ! JAK3_HUMAN relationship: has_participant CCO:B0005902 ! LEPR_HUMAN [Term] id: CCO:I0007346 name: khdrbs1-stat3-1 physical interaction comment: Interaction between Sam68 and STAT3 demonstrated by coimmunoprecipitation xref: IntAct:EBI-518702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:I0007347 name: khdrbs1-stat3-2 physical interaction comment: Interaction between Sam68 and STAT3 demonstrated by coimmunoprecipitation xref: IntAct:EBI-518705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN [Term] id: CCO:I0007348 name: birc5-casp9 physical interaction comment: The baculoviral IAP repeat-containing protein 5 (Survivin) interacts with the Casp9 (caspase 9) protein xref: IntAct:EBI-518846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0005903 ! CASP9_HUMAN [Term] id: CCO:I0007349 name: cdkn1a-ccne1-5 physical interaction comment: Co IP : bait= p21-CIP1, prey = cyclin E1 xref: IntAct:EBI-519724 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0007350 name: cdk2-rb1-1 phosphorylation comment: phosphorylation of Rb by cdk2 / cyclin E complex xref: IntAct:EBI-520059 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007351 name: cdk2-rb1-2 phosphorylation comment: phosphorylation of Rb by cdk2 / cyclin A complex xref: IntAct:EBI-520074 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007352 name: cables1-tp53-3 physical interaction comment: Interaction between human Cables1 and human p53 demonstrated by coimmunoprecipitation xref: IntAct:EBI-604641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001994 ! CABL1_HUMAN [Term] id: CCO:I0007353 name: tacc1-aurkb-5 physical interaction comment: Interaction between TACC1 and AURKB1 identified by coimmunoprecipitation xref: IntAct:EBI-624347 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:I0007354 name: tacc1-tdrd7-1 physical interaction comment: Identification of TACC1 interacting partners by Y2H xref: IntAct:EBI-624501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0005496 ! TDRD7_HUMAN [Term] id: CCO:I0007355 name: hcfc1-many-2 physical interaction comment: interaction cosedimentation of Hcfc1, Sin3A, Ash2 and Sp1 in high-molecular-weight complexes xref: IntAct:EBI-630020 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005485 ! SP1_HUMAN relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN [Term] id: CCO:I0007356 name: pb1-arid2-3 physical interaction comment: copurification by gel-filtration of a baf180 and baf200 containing complex xref: IntAct:EBI-637861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0007357 name: sept1-aurkb-1 physical interaction comment: Interaction of Septin1 and Aurora-B identified by Y2H xref: IntAct:EBI-693011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:I0007358 name: blm-terf2-2 physical interaction comment: In vivo Co-IP: bait= BLM, prey =TRF2 xref: IntAct:EBI-710858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0007359 name: blm-terf2-5 colocalization comment: Colocalization of BLM and TRF2 (TERF2) in VA13/2RA cells xref: IntAct:EBI-710884 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0007360 name: adam17-mad2l1-2 physical interaction xref: IntAct:EBI-78232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0005712 ! ADA17_HUMAN [Term] id: CCO:I0007361 name: p53-p300-1 physical interaction comment: Interaction between human p53 and human p300 detected by coIP xref: IntAct:EBI-866432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN [Term] id: CCO:I0007362 name: p53-jmy-1 physical interaction comment: Interaction between human p53 and human JMY detected by coIP xref: IntAct:EBI-866445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0040022 ! JMY_HUMAN [Term] id: CCO:I0007363 name: pole3-pole4-3 physical interaction comment: Interaction between POLE1, POLE2, POLE3 and POLE4 identified by coimmunoprecipitation xref: IntAct:EBI-867115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN relationship: has_participant CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:I0007364 name: pole3-pole4-4 physical interaction comment: Interaction between POLE1, POLE3 and POLE4 identified by coimmunoprecipitation xref: IntAct:EBI-867125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:I0007365 name: erbb1-erbb3-2 physical interaction comment: Interaction between human erbB1 and erbB3 detected by coIP xref: IntAct:EBI-875494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN [Term] id: CCO:I0007366 name: erbb1-erbb4-2 physical interaction comment: Interaction between human erbB1 and erbB4 detected by coIP xref: IntAct:EBI-875497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:I0007367 name: trrap-brca1 direct interaction comment: Direct interaction determined by pull down. xref: IntAct:EBI-896526 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:I0007368 name: pcaf-p66a physical interaction xref: IntAct:EBI-923601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005907 ! P66A_HUMAN [Term] id: CCO:I0007369 name: pcaf-p66b-1 physical interaction xref: IntAct:EBI-923606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005908 ! P66B_HUMAN [Term] id: CCO:I0007370 name: tcf4-daxx-3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the TCF-4 protein and Daxx protein xref: IntAct:EBI-924872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007371 name: disc1-atf5-4 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-929259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0007372 name: sept5-sept11-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between SEPT5 protein and SEPT11 protein xref: IntAct:EBI-958101 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002169 ! SEP11_HUMAN [Term] id: CCO:I0007373 name: sept5-sept8-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between SEPT5 protein and SEPT8 protein xref: IntAct:EBI-958139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002015 ! SEPT8_HUMAN relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN [Term] id: CCO:I0007374 name: bcl10-akt1-4 physical interaction comment: Phosphorylation of BCL10 by Akt1 xref: IntAct:EBI-958972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:I0007375 name: kras-rassf2-1 physical interaction xref: IntAct:EBI-960034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0001646 ! RASF2_HUMAN [Term] id: CCO:I0007376 name: sept11-sept5-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between SEPT11 protein and SEPT5 protein xref: IntAct:EBI-962919 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002169 ! SEP11_HUMAN [Term] id: CCO:I0007377 name: cdc25c-chek1-1 phosphorylation comment: Phosphorylation of CDC25C by Chk1 xref: IntAct:EBI-974484 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN [Term] id: CCO:I0007378 name: calm1-obscn-1 physical interaction xref: IntAct:EBI-983088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005645 ! OBSCN_HUMAN [Term] id: CCO:I0007379 name: csnk2a1-pml phosphorylation xref: IntAct:EBI-983533 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0005428 ! CSK21_HUMAN [Term] id: CCO:I0007380 name: phb-tp53-2 colocalization comment: Colocalisation of Prohibitin and p53 protein xref: IntAct:EBI-985207 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN [Term] id: CCO:I0007381 name: ubp7-daxx-6 physical interaction xref: IntAct:EBI-992640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007382 name: shoc2-erbb2ip physical interaction xref: IntAct:EBI-993893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0005650 ! SHOC2_HUMAN [Term] id: CCO:I0007383 name: shoc2-erbb2ip-3 physical interaction xref: IntAct:EBI-994100 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0005650 ! SHOC2_HUMAN [Term] id: CCO:I0007384 name: usp7-tp53 physical interaction xref: IntAct:EBI-996340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007385 name: usp7-tp53-1 physical interaction xref: IntAct:EBI-996378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007386 name: usp7-tp53-2 physical interaction xref: IntAct:EBI-996406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007387 name: usp7-mdm2 physical interaction xref: IntAct:EBI-996470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007388 name: usp7-mdm2-1 physical interaction xref: IntAct:EBI-996499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007389 name: usp7-mdm2-2 physical interaction xref: IntAct:EBI-996511 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007390 name: sch1-app-4 physical interaction comment: shcA-APP C99 xref: IntAct:EBI-79039 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007391 name: adam15-mad2l2-1 physical interaction xref: IntAct:EBI-77900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0005909 ! ADA15_HUMAN [Term] id: CCO:I0007392 name: cdk4-cdc37 physical interaction comment: Interaction between cdc37 and cdk4 confirmed by Y2H xref: IntAct:EBI-295659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001819 ! CDC37_HUMAN [Term] id: CCO:I0007393 name: cdk6-cdc37 physical interaction comment: Interaction between cdc37 and cdk6 confirmed by Y2H xref: IntAct:EBI-295662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0001819 ! CDC37_HUMAN [Term] id: CCO:I0007394 name: incenp-cbx5-2 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-307776 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:I0007395 name: cbx5-incenp-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-307779 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:I0007396 name: cdc37-hsp90 physical interaction comment: Interaction of Cdc37, Hsp90 and Akt1 demonstrated by western blot xref: IntAct:EBI-296045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0007397 name: cdc37-akt1 physical interaction comment: Interaction of Cdc37 and Akt1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-296086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:I0007398 name: cdc37-akt2 physical interaction comment: Interaction of Cdc37-Akt2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-296109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005910 ! AKT2_HUMAN [Term] id: CCO:I0007399 name: cdc37-akt3 physical interaction comment: Interaction of Cdc37 and Akt3 demonstrated by coimmunoprecipitation xref: IntAct:EBI-296114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0005911 ! AKT3_HUMAN [Term] id: CCO:I0007400 name: mcc-nfkbib physical interaction comment: Interaction of MCC1 and IkBbeta xref: IntAct:EBI-352972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001549 ! CRCM_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0007401 name: hras-ras physical interaction comment: Interactions of human Rit2 identified by Y2H xref: IntAct:EBI-365960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0005913 ! BRAF1_HUMAN relationship: has_participant CCO:B0005914 ! AFAD_HUMAN [Term] id: CCO:I0007402 name: fance-fanca-1 physical interaction comment: The constituents of the Fanconi anaemia nuclear complex identified by coimmunoprecipitation xref: IntAct:EBI-396813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0005576 ! FANCE_HUMAN [Term] id: CCO:I0007403 name: fance-fanca-2 physical interaction comment: Components of the Fanconi anaemia complex identified by coimmunoprecipitation xref: IntAct:EBI-396822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0005576 ! FANCE_HUMAN [Term] id: CCO:I0007404 name: fance-fancd2-1 physical interaction comment: Interaction between endogenous FANCE and FANCD2 xref: IntAct:EBI-446094 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0005576 ! FANCE_HUMAN [Term] id: CCO:I0007405 name: cdt1-gmnn-2 physical interaction comment: Interaction between Geminin and CDT1 identified by coimmunoprecipitation xref: IntAct:EBI-456960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:I0007406 name: cdt1-gmnn-3 physical interaction comment: Interaction between Geminin and CDT1 identified by coimmunoprecipitation xref: IntAct:EBI-456966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:I0007407 name: mdm2-mdm4-4 physical interaction comment: MDMX and MDM2 interaction detected by co-immunoprecipitation. xref: IntAct:EBI-399651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0007408 name: map3k4-map2k61 physical interaction comment: Interaction between MAP3K4 and MAP2K6 demonstrated by Y2H xref: IntAct:EBI-448103 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0005915 ! M3K4_HUMAN [Term] id: CCO:I0007410 name: c20orf20-epc1-4 physical interaction comment: Interaction detected by comigration through a Suparose 6 gel. xref: IntAct:EBI-399301 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005916 ! EP400_HUMAN relationship: has_participant CCO:B0005917 ! MO4L1_HUMAN [Term] id: CCO:I0007411 name: app-apbb1-6 physical interaction comment: Interacting partners of human APP from brains samples derived from Alzheimers patients xref: IntAct:EBI-960396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:I0007412 name: krs-rassf2-2 direct interaction xref: IntAct:EBI-960104 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0001646 ! RASF2_HUMAN [Term] id: CCO:I0007413 name: nyd_sp25-tpd53 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between Nyd-SP25 protein and TPD53 protein xref: IntAct:EBI-932183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0005918 ! TPD55_HUMAN [Term] id: CCO:I0007414 name: cdc73-ctnnb1-1 physical interaction xref: IntAct:EBI-932396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007415 name: cdc73-ctnnb1-2 physical interaction xref: IntAct:EBI-932408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007416 name: cdc73-ctnnb1-5 physical interaction xref: IntAct:EBI-932455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007417 name: p300-tfap2a-6 physical interaction comment: Interaction between human p300 and TFAP2A detected by mammalian two-hybrid xref: IntAct:EBI-937888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0007418 name: rb1-pa2g4-1 physical interaction xref: IntAct:EBI-925098 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN [Term] id: CCO:I0007419 name: uhrf2-cdk2-2 physical interaction comment: Interaction between UHRF2 (NIRF) and CDK2 identified by GST pulldown xref: IntAct:EBI-625362 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0002054 ! UHRF2_HUMAN [Term] id: CCO:I0007420 name: disc1-atf5-2 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-929168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0007421 name: gpsm2-numa1-2 physical interaction xref: IntAct:EBI-618747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0007422 name: blm-c9orf76-2 physical interaction comment: coimmunoprecipitation: bait = BLM, preys = BLAP75, RPA32, TOPOIIIalpha xref: IntAct:EBI-621447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001753 ! TOP3A_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:I0007423 name: tacc1-aurkb-4 physical interaction comment: Interaction between TACC1 and AURKB1 identified by coimmunoprecipitation xref: IntAct:EBI-624334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN [Term] id: CCO:I0007424 name: zn655-cdk4-1 physical interaction comment: Interaction between ZN655 (VIK) and CDK4 confirmed by GST pulldown xref: IntAct:EBI-625679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0005578 ! ZN655_HUMAN [Term] id: CCO:I0007425 name: trx-jab1-4 physical interaction comment: GST pulldown analysis reveals interaction between thioredoxin and the COP9 signalosome complex subunit 5 protein xref: IntAct:EBI-594716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002025 ! CSN5_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:I0007426 name: cdkn2a-huew1-2 physical interaction comment: gst pull down: bait = p14arf, prey = arf-bp1/mule xref: IntAct:EBI-626064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:I0007427 name: c9orf76-blm-2 physical interaction comment: coimmunoprecipitation: bait = BLAP75, preys = BLM, RPA32, TOPOIIIalpha xref: IntAct:EBI-621441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001753 ! TOP3A_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:I0007428 name: egfr-pik3c2b-3 direct interaction comment: Interaction of PIK3C2B and EGFR demonstrated by competition binding xref: IntAct:EBI-641269 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN [Term] id: CCO:I0007429 name: egfr-pik3c2b-6 direct interaction comment: Interaction of PIK3C2B and EGFR demonstrated by competition binding xref: IntAct:EBI-641334 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN [Term] id: CCO:I0007430 name: gnl3-ppp2r5a-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the nucleostemin protein and PPP2R5A protein xref: IntAct:EBI-641685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002103 ! GNL3_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0007431 name: ppp2r5a-gnl3 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the nucleostemin protein and PPP2R5A protein xref: IntAct:EBI-641698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002103 ! GNL3_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0007432 name: fgf-fgfr-2 direct interaction comment: Interaction between FGF and FGFR3 determined by surface plasmon resonance xref: IntAct:EBI-698188 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0007433 name: fgf-fgfr-3 direct interaction comment: Interaction between FGF and FGFR3 determined by surface plasmon resonance xref: IntAct:EBI-698242 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0007434 name: tp53-hipk1-1 physical interaction comment: Interaction between p53 and HIPK1 identified by coimmunoprecipitation xref: IntAct:EBI-692887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005675 ! HIPK1_HUMAN [Term] id: CCO:I0007435 name: fgf-fgfr-1 direct interaction comment: Interaction between FGF and FGFR3 determined by X-ray crystallography xref: IntAct:EBI-698079 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0007436 name: wrn-rad52-1 physical interaction comment: Y2H: bait= RAD52, prey= WRN xref: IntAct:EBI-706461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007437 name: rad52-rad52-1 physical interaction comment: Y2H: bait= RAD52, prey= RAD52 xref: IntAct:EBI-706466 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001621 ! RAD52_HUMAN [Term] id: CCO:I0007438 name: rad52-rad51-1 physical interaction comment: Y2H: bait= RAD52, prey= RAD51 xref: IntAct:EBI-706470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007439 name: wrn-rad52-2 direct interaction comment: far-western: bait= WRN, prey= RAD52 xref: IntAct:EBI-706482 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007440 name: wrn-rad52-3 direct interaction comment: far-western: bait= RAD52, prey= WRN xref: IntAct:EBI-706488 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007441 name: wrn-rad52-4 direct interaction comment: CoIP: bait= WRN, prey= RAD52 xref: IntAct:EBI-706506 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007442 name: wrn-rad52-5 direct interaction comment: Co-IP bait= RAD52, prey= WRN xref: IntAct:EBI-706513 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007443 name: bad-bcl2-1 physical interaction comment: Interaction of BAD and BCL2 identified by yeast 2-hybrid xref: IntAct:EBI-706597 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:I0007444 name: bad-bcl2-2 physical interaction comment: Interaction of BAD and BCL2 identified by ELISA xref: IntAct:EBI-706610 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:I0007445 name: bax-bcl2-1 physical interaction comment: Interaction of BAX and BCL2 identified by ELISA xref: IntAct:EBI-706803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN [Term] id: CCO:I0007446 name: cdh1-ctnna1 physical interaction comment: Biosensor-Based Micro-Affinity Purification using GST epitope reveals interaction between CDH1 and CTNNA1 proteins xref: IntAct:EBI-727492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005581 ! CADH1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0005824 ! CTNA1_HUMAN relationship: has_participant CCO:B0048975 ! TGM2_HUMAN [Term] id: CCO:I0007447 name: apc-ctbb1 physical interaction comment: Biosensor-Based Micro-Affinity Purification using GST epitope reveals interaction between APC and CTBB1 proteins xref: IntAct:EBI-727740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0005823 ! K2C1_HUMAN relationship: has_participant CCO:B0005921 ! IGHA1_HUMAN relationship: has_participant CCO:B0005922 ! K1C9_HUMAN [Term] id: CCO:I0007448 name: tgfb2-bapp-1 physical interaction comment: Interaction between transforming growth factor beta and beta amyloid precursor protein detected by chromatography xref: IntAct:EBI-779604 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007449 name: bmx-tp53-1 physical interaction comment: Interaction between BMX/Etk and p53 determined by coimmunoprecipitation xref: IntAct:EBI-847661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005923 ! BMX_HUMAN [Term] id: CCO:I0007450 name: hdac3-mbd1 physical interaction comment: Interaction between MBD1 and FLAG tagged HDAC3 determined by anti tag CoIP. xref: IntAct:EBI-867192 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001376 ! HDAC3_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0007451 name: tp53-lap-1 physical interaction comment: Coimmunoprecipitation assay reveals interaction between p53 protein and LAP (full length CCAAT/enhancer-binding protein beta) protein xref: IntAct:EBI-970335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN [Term] id: CCO:I0007452 name: ttn-obscn-2 physical interaction xref: IntAct:EBI-966795 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005645 ! OBSCN_HUMAN [Term] id: CCO:I0007453 name: gab2-grb2-1 physical interaction comment: Interaction between GAB2, GRB2 and PTN11 xref: IntAct:EBI-975219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005924 ! GAB2_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:I0007454 name: brca1-trrap physical interaction comment: Interaction detected by pulldown. xref: IntAct:EBI-896361 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN [Term] id: CCO:I0007455 name: brca1-trrap-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-896453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN [Term] id: CCO:I0007456 name: cenph_kntc2_1 physical interaction xref: IntAct:EBI-1003699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0005682 ! CENPH_HUMAN [Term] id: CCO:I0007457 name: eb1-apc-1 physical interaction comment: Interaction between human EB1 and APC detected by pulldown xref: IntAct:EBI-1004194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:I0007458 name: eb1-pin2_trf1-1 physical interaction comment: Interaction between human EB1 and PIN2/TRF1 detected by pulldown xref: IntAct:EBI-1004214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:I0007459 name: suv39h1-hdac2-3 physical interaction xref: IntAct:EBI-994880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0007460 name: suv39h1-hdac1-3 physical interaction xref: IntAct:EBI-994888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0007461 name: usp7-tp53-3 direct interaction xref: IntAct:EBI-996806 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007462 name: usp7-mdm2-5 direct interaction xref: IntAct:EBI-997298 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007463 name: kntc2-cdca1-2 physical interaction xref: IntAct:EBI-999882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN [Term] id: CCO:I0007464 name: spbc24-spbc25-1 physical interaction xref: IntAct:EBI-999899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0007465 name: spbc24-spbc25-2 physical interaction xref: IntAct:EBI-999928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0007466 name: shoc2-erbb2ip-1 physical interaction xref: IntAct:EBI-993998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0005650 ! SHOC2_HUMAN [Term] id: CCO:I0007467 name: tp53-tp53bp2-1 direct interaction comment: P53-53bp2 complex xref: IntAct:EBI-1026207 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN [Term] id: CCO:I0007468 name: flt1-vegf-2 direct interaction comment: Vascular endothelial growth factor in complex with domain 2 of the flt-1 receptor xref: IntAct:EBI-1028540 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:I0007469 name: fgf1-fgfr2-2 direct interaction comment: Crystal structure of a ternary fgf1-fgfr2-heparin complex xref: IntAct:EBI-1030096 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0005381 ! FGFR2_HUMAN [Term] id: CCO:I0007470 name: flt1-pgf-1 direct interaction comment: Crystal structure of plgf in complex with domain 2 of vegfr1 xref: IntAct:EBI-1037666 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001633 ! PLGF_HUMAN relationship: has_participant CCO:B0005719 ! VGFR1_HUMAN [Term] id: CCO:I0007471 name: ran-rcc1-1 direct interaction comment: Ran-rcc1-so4 complex xref: IntAct:EBI-1031180 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN [Term] id: CCO:I0007472 name: rin1-hras-3 physical interaction comment: Interaction between Rin1 and H-Ras identified by coimmunoprecipitation xref: IntAct:EBI-1102897 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0007473 name: kntc2-cdca1-1 physical interaction xref: IntAct:EBI-1101356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN [Term] id: CCO:I0007474 name: lkb1-strad-1 physical interaction comment: Interaction between STRAD and LKB1 determined by yeast 2-hybrid. xref: IntAct:EBI-1109128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN [Term] id: CCO:I0007475 name: pms2-mlh1 direct interaction xref: IntAct:EBI-1162573 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0001669 ! PMS2_HUMAN [Term] id: CCO:I0007476 name: bhlbh2-ube2i-2 physical interaction xref: IntAct:EBI-1164864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN [Term] id: CCO:I0007477 name: smarca2-sam68 physical interaction xref: IntAct:EBI-1168682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:I0007478 name: cftr-ebp physical interaction xref: IntAct:EBI-1170380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN relationship: has_participant CCO:B0006123 ! BCR_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN relationship: has_participant CCO:B0043427 ! PSME2_HUMAN relationship: has_participant CCO:B0049439 ! RYR2_HUMAN relationship: has_participant CCO:B0051700 ! S10A7_HUMAN relationship: has_participant CCO:B0063014 ! AHSA1_HUMAN relationship: has_participant CCO:B0063206 ! HSP77_HUMAN relationship: has_participant CCO:B0063208 ! SNX4_HUMAN relationship: has_participant CCO:B0063211 ! SQRD_HUMAN relationship: has_participant CCO:B0063286 ! LEG3_HUMAN relationship: has_participant CCO:B0063287 ! G8_HUMAN relationship: has_participant CCO:B0063288 ! B3GN9_HUMAN relationship: has_participant CCO:B0063289 ! CH055_HUMAN [Term] id: CCO:I0007479 name: cftr-atp2a2 physical interaction xref: IntAct:EBI-1171360 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002240 ! EXO1_HUMAN relationship: has_participant CCO:B0005330 ! ZO1_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005460 ! CLH2_HUMAN relationship: has_participant CCO:B0005581 ! CADH1_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0005840 ! AT2A2_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN relationship: has_participant CCO:B0005961 ! GRN_HUMAN relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0018655 ! RYK_HUMAN relationship: has_participant CCO:B0027154 ! S61A1_HUMAN relationship: has_participant CCO:B0030251 ! GNA11_HUMAN relationship: has_participant CCO:B0054687 ! WFS1_HUMAN relationship: has_participant CCO:B0054863 ! APOA2_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0055325 ! ADCY8_HUMAN relationship: has_participant CCO:B0055865 ! TIAM1_HUMAN relationship: has_participant CCO:B0059132 ! LIMA1_HUMAN relationship: has_participant CCO:B0059406 ! WSB1_HUMAN relationship: has_participant CCO:B0062934 ! HAX1_HUMAN relationship: has_participant CCO:B0062985 ! PIMT_HUMAN relationship: has_participant CCO:B0063054 ! TPM3_HUMAN relationship: has_participant CCO:B0063067 ! CALX_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN relationship: has_participant CCO:B0063097 ! TMOD3_HUMAN relationship: has_participant CCO:B0063201 ! EPN4_HUMAN relationship: has_participant CCO:B0063206 ! HSP77_HUMAN relationship: has_participant CCO:B0063211 ! SQRD_HUMAN relationship: has_participant CCO:B0063287 ! G8_HUMAN relationship: has_participant CCO:B0063290 ! XPP3_HUMAN relationship: has_participant CCO:B0063291 ! ZO3_HUMAN relationship: has_participant CCO:B0063292 ! SAP_HUMAN relationship: has_participant CCO:B0063293 ! LIN7C_HUMAN [Term] id: CCO:I0007480 name: fyn-med28-4 physical interaction comment: Interaction between Fyn, Lck and MED28 identified by coimmunoprecipitation xref: IntAct:EBI-1206908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0007481 name: cdn1b-cdk2-3 physical interaction comment: Interaction between CDN1B (p27), Cyclin E1 and CDK2 identified by coimmunoprecipitation xref: IntAct:EBI-1201257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007482 name: tcf7l2-ctnnb1-8 physical interaction comment: PARP1, Ku70 and Ku80 and beta-catenin coimmunoprecipitate with FLAG-TCF-4 (TCF7L2) in HCT116 nuclear extract xref: IntAct:EBI-1201296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0007483 name: g22p1-tcf7l2 physical interaction comment: FLAG-TCF-4 coimmunoprecipitates Myc-Ku70 in HEK293 cell lysate xref: IntAct:EBI-1201373 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0007484 name: cdn1b-cdk2-4 physical interaction comment: Interaction between CDN1B (p27), Cyclin E1 and CDK2 identified by coimmunoprecipitation xref: IntAct:EBI-1201327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007485 name: cdn1b-cdk2-5 physical interaction comment: Interaction between CDN1B (p27), Cyclin E1 and CDK2 identified by coimmunoprecipitation xref: IntAct:EBI-1201337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007486 name: cdkn1b-lyn-1 physical interaction comment: Interaction between CDKN1B (p27) and lyn demonstrated by coimmunoprecipitation xref: IntAct:EBI-1201624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:I0007487 name: cdkn1b-cdk2-1 physical interaction comment: interaction between CDKN1B, CDK2 and CCNA2 demonstrated by gel filtration xref: IntAct:EBI-1201766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007488 name: cdkn1b-cdk2-5 phosphorylation comment: Phosphorylation of CDKN1B by CDK2 and CCNA2 xref: IntAct:EBI-1201901 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007489 name: ndel1_pafah1b1_1 physical interaction xref: IntAct:EBI-1009436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN [Term] id: CCO:I0007490 name: pafah1b1_ndel1_1 physical interaction xref: IntAct:EBI-1009478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN [Term] id: CCO:I0007491 name: phb-tp53-4 colocalization comment: Colocalisation of Prohibitin and p53 protein xref: IntAct:EBI-1017388 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN [Term] id: CCO:I0007492 name: esr1-brca1-1 direct interaction xref: IntAct:EBI-1017529 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0007493 name: esr1-brca1-2 direct interaction xref: IntAct:EBI-1024834 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0007494 name: esr1-brca1-3 direct interaction xref: IntAct:EBI-1024855 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0007495 name: esr1-brca1-6 direct interaction xref: IntAct:EBI-1025018 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0007496 name: rb1-e2f1 physical interaction xref: IntAct:EBI-1025557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0007497 name: fgf2-fgfr1-1 direct interaction comment: Crystal structure of a dimeric fgf2-fgfr1 complex xref: IntAct:EBI-1028412 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0005868 ! FGFR1_HUMAN [Term] id: CCO:I0007498 name: rpa1-rpa2-3 physical interaction comment: Structure of the human replication protein a (rpa) trimerization core xref: IntAct:EBI-1033227 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005501 ! RFA3_HUMAN [Term] id: CCO:I0007499 name: ccna2-cdk2-4 direct interaction comment: Structure of human thr160-phospho cdk2-cyclin a complexed with the inhibitor nu2058 xref: IntAct:EBI-1034334 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007500 name: ccna2-cdk2-5 direct interaction comment: Structure of human thr160-phospho cdk2-cyclin a complexed with the inhibitor nu6094 xref: IntAct:EBI-1034344 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007501 name: ccna2-cdk2-6 direct interaction comment: Structure of human thr160-phospho cdk2-cyclin a complexed with the inhibitor nu6086 xref: IntAct:EBI-1034354 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007502 name: ccna2-cdk2-7 direct interaction comment: Structure of human thr160-phospho cdk2-cyclin a complexed with the inhibitor nu6102 xref: IntAct:EBI-1034364 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007503 name: egf-egfr-3 direct interaction comment: Structure of the extracellular domain of human epidermal growth factor (egf) receptor in an inactive (low ph) complex with egf. xref: IntAct:EBI-1035794 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN [Term] id: CCO:I0007504 name: cand1-cul1-5 physical interaction comment: Crystal structure of the cand1-cul1-roc1 complex xref: IntAct:EBI-1040799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN [Term] id: CCO:I0007505 name: zo_1-actn4-6 physical interaction xref: IntAct:EBI-1103429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005330 ! ZO1_HUMAN [Term] id: CCO:I0007506 name: fnbp1-dnm2-1 colocalization xref: IntAct:EBI-1111754 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0005386 ! FNBP1_HUMAN [Term] id: CCO:I0007507 name: yeats4-tacc1 physical interaction xref: IntAct:EBI-1151709 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN [Term] id: CCO:I0007508 name: tacc1-yeats4-3 colocalization xref: IntAct:EBI-1151783 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN [Term] id: CCO:I0007509 name: pin1-nek6-2 physical interaction comment: Interaction between PIN1 and NEK6 identified by coimmunoprecipitation xref: IntAct:EBI-1164681 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN [Term] id: CCO:I0007510 name: pin1-nek6-3 colocalization comment: Interaction between PIN1 and NEK6 identified by colocalisation xref: IntAct:EBI-1164699 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN [Term] id: CCO:I0007511 name: bhlbh2-ube2i-1 physical interaction xref: IntAct:EBI-1164847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN [Term] id: CCO:I0007512 name: smarca2-sam68-1 physical interaction xref: IntAct:EBI-1168763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN [Term] id: CCO:I0007513 name: ppp2r5d-cdc25c-1 physical interaction comment: Interaction between PPP2R5D and CDC25c idnetified by cimmunoprecipitation xref: IntAct:EBI-1170666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN [Term] id: CCO:I0007514 name: h3_peptide-cul4a physical interaction xref: IntAct:EBI-1177834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005927 ! H33_HUMAN [Term] id: CCO:I0007515 name: stat5b-nmi-1 physical interaction comment: Interaction between human Stat5b and Nmi detected by Y2H xref: IntAct:EBI-1186134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007516 name: egfr-cav1-clca physical interaction xref: IntAct:EBI-1188189 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005448 ! CLCA_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0005461 ! S10A9_HUMAN relationship: has_participant CCO:B0005463 ! 4F2_HUMAN [Term] id: CCO:I0007517 name: tcf7l2-g22p1-1 physical interaction comment: Ku70 coimmunoprecipitates with FLAG-TCF-4 in HEK293 cell lysate in the absence of PARP1 xref: IntAct:EBI-1201402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0007518 name: bcl2-vrk2 physical interaction comment: Bcl-2 interacts weakly with VRK2 in a yeast two-hybrid assay xref: IntAct:EBI-1207847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005928 ! VRK2_HUMAN [Term] id: CCO:I0007519 name: lck-khdrbs1 physical interaction comment: Interaction between Lck-KHDRBS1 and Sam68 xref: IntAct:EBI-1375 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:I0007520 name: pard6a-prcki-1 physical interaction comment: Interaction between deletions of PAR-6 and aPKCl/i determined by Y2H. xref: IntAct:EBI-286214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007521 name: prcki-pard6a-1 physical interaction comment: Interaction between deletions of aPKCi and PARD6 determined by Y2H. xref: IntAct:EBI-286219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN [Term] id: CCO:I0007522 name: rad51-rad51-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-297242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007523 name: brap-brca1 physical interaction comment: Interaction of BRAP with BCRA1 detected by Y2H xref: IntAct:EBI-349930 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:I0007524 name: brca1-brap physical interaction comment: BRAP binds to the nuclear localisation signal of BRCA1 - Y2H xref: IntAct:EBI-349934 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:I0007525 name: kpna2-brca1 physical interaction comment: Importin alpha-2 binds to the nuclear localisation signal of BRCA1 - Y2H xref: IntAct:EBI-349937 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001657 ! IMA2_HUMAN [Term] id: CCO:I0007526 name: hmgb1-tp73-1 physical interaction comment: Direct interactions between HMGB1 and p73-alpha as revealed by pull-down assay. xref: IntAct:EBI-389651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN [Term] id: CCO:I0007527 name: abi1-abl1-1 physical interaction xref: IntAct:EBI-389880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005703 ! ABI1_HUMAN [Term] id: CCO:I0007529 name: hif1a-ep300-2 physical interaction comment: Interaction of HIF1A with EP300 detected by mammalian two-hybrid system. xref: IntAct:EBI-447490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:I0007530 name: map3k4-gadd45 physical interaction comment: GADD45/MAP3K4/MAP2K6 interaction identified by Y3H xref: IntAct:EBI-448179 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001552 ! GA45A_HUMAN relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0005915 ! M3K4_HUMAN [Term] id: CCO:I0007531 name: map3k4-gadd45-2 physical interaction comment: GADD45/MAP3K4/MAP2K6 interaction identified by Y3H xref: IntAct:EBI-448183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001424 ! GA45B_HUMAN relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0005915 ! M3K4_HUMAN [Term] id: CCO:I0007532 name: map3k4-gadd45-3 physical interaction comment: GADD45/MAP3K4/MAP2K6 interaction identified by Y3H xref: IntAct:EBI-448198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0005915 ! M3K4_HUMAN [Term] id: CCO:I0007533 name: cdt1-cdk2-1 physical interaction comment: Interaction between CTD1 and cyclin-dependent protein kinases demonstrated by coimmunoprecipitation xref: IntAct:EBI-457093 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:I0007534 name: sirt2-pcaf-1 physical interaction comment: Interaction between SIRT2 and PCAF demonstrated by CoIP. xref: IntAct:EBI-477370 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN [Term] id: CCO:I0007535 name: sirt2-pcaf-2 physical interaction comment: Interaction between SIRT2 and PCAF demonstrated by CoIP. xref: IntAct:EBI-477484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN [Term] id: CCO:I0007536 name: sirt2-pcaf-myod1-1 physical interaction comment: Interaction between SIRT2, PCAF and MYOD1 detected by CoIP. xref: IntAct:EBI-488593 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0005705 ! MYOD1_HUMAN [Term] id: CCO:I0007537 name: orc1-skp2-1 physical interaction comment: Interaction of hORC1 with SKP2 xref: IntAct:EBI-492406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:I0007538 name: h2afx-nbs1-5 physical interaction xref: IntAct:EBI-495266 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0007539 name: orc2-mcm3-1 physical interaction comment: Interaction between Orc2 and Mcm3 by coimmunoprecipitation xref: IntAct:EBI-515223 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0007540 name: mcm3-mcm5-1 physical interaction comment: Immunoprecipitation of an Mcm protein complex xref: IntAct:EBI-515228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0007541 name: mcm3-mcm5-2 physical interaction comment: Immunoprecipitation of an Mcm protein complex xref: IntAct:EBI-515234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN [Term] id: CCO:I0007542 name: mcm4-mcm6-1 physical interaction comment: Mcm4-Mcm6-Mcm7 complex identified by co-immunoprecipitation xref: IntAct:EBI-515243 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:I0007543 name: cam-cd95-2 physical interaction comment: The CD95 (Fas) protein binds to calmodulin in vivo xref: IntAct:EBI-518173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN [Term] id: CCO:I0007544 name: cdk4-ccnd1-1 physical interaction comment: co-IP: bait = cyclin D1, prey = cdk4 xref: IntAct:EBI-519187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:I0007545 name: cdk4-ccnd1-2 physical interaction comment: co-IP: bait = cdk4, prey = cyclin D1 xref: IntAct:EBI-519196 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:I0007546 name: cdk4-cdkn1c-1 physical interaction comment: co-IP: bait = cdk4, prey = KIP2 xref: IntAct:EBI-519276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN [Term] id: CCO:I0007547 name: cdk4-cdkn1b-1 physical interaction comment: co-IP: bait = cdk4, prey = KIP1 xref: IntAct:EBI-519297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007548 name: cdk4-cdkn1a-1 physical interaction comment: co-IP: bait= p21-CIP1, prey = cdk4 xref: IntAct:EBI-519303 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0007549 name: cdk4-ccnd3-1 physical interaction comment: co-IP: bait = cdk4, prey = cyclin D3 xref: IntAct:EBI-519309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN [Term] id: CCO:I0007550 name: cdk4-ccnd3-2 physical interaction comment: co-IP: bait = cyclin D3, prey = cdk4 xref: IntAct:EBI-519350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN [Term] id: CCO:I0007551 name: dapk-erk-2 physical interaction comment: Yeast-2-hybrid reveals interaction between death-associated protein kinase 1protein and the mitogen-activated protein kinase 3 protein xref: IntAct:EBI-525623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0005482 ! DAPK1_HUMAN [Term] id: CCO:I0007552 name: rent1-stau-1 physical interaction xref: IntAct:EBI-536589 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0005483 ! STAU1_HUMAN [Term] id: CCO:I0007553 name: araf-hras physical interaction comment: Y2H: bait = A-Raf ,prey = HA-Ras-C-Ha-ras p21 protein xref: IntAct:EBI-537048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:I0007554 name: araf-pbk-1 physical interaction comment: Y2H: bait = A-Raf ,prey = TOPK/BPK-MPAKK-like protein kinase cap site form 2 xref: IntAct:EBI-537076 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002045 ! TOPK_HUMAN relationship: has_participant CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:I0007555 name: araf-pbk-2 physical interaction comment: Y2H: bait = A-Raf ,prey = TOPK/BPK-MPAKK-like protein kinase cap site form 2 xref: IntAct:EBI-537146 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002045 ! TOPK_HUMAN relationship: has_participant CCO:B0005708 ! ARAF_HUMAN [Term] id: CCO:I0007556 name: cdn1b-kpna3-1 physical interaction comment: FLAG pull-down : bait = p27 KIP1, prey= importin alpha 3 xref: IntAct:EBI-540571 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005931 ! IMA3_HUMAN [Term] id: CCO:I0007557 name: cdn1b-kpna3-2 physical interaction comment: FLAG pull-down : bait = p27 KIP1, prey= importin alpha 3, prey = importin beta xref: IntAct:EBI-540594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005931 ! IMA3_HUMAN [Term] id: CCO:I0007558 name: cdn1b-kpna5-1 physical interaction comment: FLAG pull-down : bait = p27 KIP1, prey= importin alpha 5, prey = importin beta xref: IntAct:EBI-540611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005697 ! IMA5_HUMAN [Term] id: CCO:I0007559 name: cdn1b-kpna5-2 physical interaction comment: FLAG pull-down : bait = p27 KIP1, prey= importin alpha 5 xref: IntAct:EBI-540624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005697 ! IMA5_HUMAN [Term] id: CCO:I0007560 name: cdn1b-kpna5-3 physical interaction comment: in vivo Co-IP : bait = p27 KIP1, prey= importin alpha 5 xref: IntAct:EBI-540640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005697 ! IMA5_HUMAN [Term] id: CCO:I0007561 name: hcfc1-sin3a-3 physical interaction comment: Immunoblot (co-ip) of interaction between hcfc1 basic region and sin3a xref: IntAct:EBI-540858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:I0007562 name: hcfc1-ash2l-2 physical interaction comment: Immunoblot (co-ip) of interaction between the kelch domain of hcfc1 and ash2l xref: IntAct:EBI-540883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN [Term] id: CCO:I0007563 name: trx-jab1-1 physical interaction comment: GST pulldown analysis reveals interaction between thioredoxin and the COP9 signalosome complex subunit 5 protein xref: IntAct:EBI-594687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002025 ! CSN5_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:I0007564 name: ubl5-sart1-1 physical interaction comment: Interaction between human ubl5 (hub1 homolog) and sart1 (snu66 homolog) via classical two hybrid xref: IntAct:EBI-607767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001388 ! SNUT1_HUMAN relationship: has_participant CCO:B0005932 ! UBL5_HUMAN [Term] id: CCO:I0007565 name: hcfc1-zbtb17-1 physical interaction comment: Y2H of interaction between hcfc1 and zbtb17 (Miz1) xref: IntAct:EBI-621532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN [Term] id: CCO:I0007566 name: tacc1-chtog-6 direct interaction comment: Regions of interaction between TACC1 and chTOG identified by GST pulldown xref: IntAct:EBI-624701 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001772 ! CKAP5_HUMAN [Term] id: CCO:I0007567 name: tacc1-tdrd7-7 physical interaction comment: Identification of regions of TACC1 which interact with TDRD7 (TRAP) by GST pulldown xref: IntAct:EBI-624727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0005496 ! TDRD7_HUMAN [Term] id: CCO:I0007568 name: tp53-huew1-1 physical interaction comment: gst pull down: bait = tp53, prey = arf-bp1/mule xref: IntAct:EBI-626140 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:I0007569 name: brg1-baf200-2 physical interaction comment: coIP: bait = brg1, preys = baf200, baf180, baf170, baf155, baf60a, baf53, snf5, actin xref: IntAct:EBI-638040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:I0007570 name: egfr-pik3c2b-4 physical interaction comment: Interaction of PIK3C2B and EGFR demonstrated by GST-pulldown xref: IntAct:EBI-641307 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN [Term] id: CCO:I0007571 name: ttn-actn2-1 physical interaction comment: Interaction of titin and alpha-actinin detected by yeast two hybrid. xref: IntAct:EBI-696133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0007572 name: pten-mast3-2 physical interaction comment: Interaction between human PTEN and Mast3 identified by Y2H betagalactosidase assay xref: IntAct:EBI-696418 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0005499 ! MAST3_HUMAN [Term] id: CCO:I0007573 name: wrn-terf2-8 direct interaction comment: ELISA: bait= WRM, prey = TRF2 (TERF2) xref: IntAct:EBI-706740 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007574 name: blm-terf2-3 direct interaction comment: ELISA: bait= BLM, prey = TRF2 (TERF2) xref: IntAct:EBI-706749 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0007575 name: g22p1-centd2-1 physical interaction comment: Interaction between G22P1 and CENTD2 detected by anti protein A antibodies COIP xref: IntAct:EBI-709999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0007576 name: htatip-dleu1-1 physical interaction comment: Interaction between HTATIP and DLEU1 detected by anti protein A antibodies COIP xref: IntAct:EBI-710053 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:I0007577 name: tp53-btbd2-1 physical interaction comment: Interaction between TP53 and BTBD2 determined by Protein A CoIP xref: IntAct:EBI-710087 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005933 ! BTBD2_HUMAN [Term] id: CCO:I0007578 name: p53-wrn-1 direct interaction comment: ELISA: bait= P53, prey =WRN xref: IntAct:EBI-711124 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007579 name: p53-wrn-2 direct interaction comment: ELISA: bait=WRN , prey =P53 xref: IntAct:EBI-711129 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007580 name: wrn-rpa1-7 physical interaction comment: ELISA: bait = human Replication Protein A RPA70 (70kDa subunit), prey =WRN xref: IntAct:EBI-711136 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007581 name: p53-rpa1-8 physical interaction comment: ELISA: bait = human Replication Protein A RPA70 (70kDa subunit), prey =P53 xref: IntAct:EBI-711148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001562 ! RFA1_HUMAN [Term] id: CCO:I0007582 name: bcl6-hdac4 physical interaction comment: Coimmunoprecipitaion reveals interaction between BCL6, HDAC4, SMRT,PKC and WNK4 xref: IntAct:EBI-766553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0005934 ! WNK4_HUMAN relationship: has_participant CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:I0007583 name: hdac4-bcl6 physical interaction comment: Coimmunoprecipitaion reveals interaction between HDAC4 and BCL6 proteins xref: IntAct:EBI-766559 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN [Term] id: CCO:I0007584 name: pkc-bcl6 physical interaction comment: Coimmunoprecipitaion reveals interaction between PKC and BCL6 xref: IntAct:EBI-766565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0005935 ! PKCB1_HUMAN [Term] id: CCO:I0007585 name: tgfb2-bapp-4 physical interaction comment: Interaction between transforming growth factor beta and beta amyloid precursor protein detected by chromatography xref: IntAct:EBI-779627 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007586 name: hd52-hd53-2 physical interaction comment: Interaction between human D52 and human D53 detected by Y2H xref: IntAct:EBI-782712 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0005373 ! TPD52_HUMAN [Term] id: CCO:I0007587 name: fancg-fancf-1 physical interaction comment: Interaction of FANCA, FANCG and FANCF detected by CoIP. xref: IntAct:EBI-81620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0005323 ! FANCA_HUMAN relationship: has_participant CCO:B0005936 ! FANCF_HUMAN [Term] id: CCO:I0007588 name: pold1-pold2-1 physical interaction comment: Assembly of DNA polymerase delta identifed by column chromotography xref: IntAct:EBI-864998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:I0007589 name: pold1-pold2-3 physical interaction comment: Assembly of DNA polymerase delta subunits 1 and 2 identifed by column chromotography xref: IntAct:EBI-865018 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN [Term] id: CCO:I0007590 name: pold1-pold4-1 direct interaction comment: Assembly of DNA polymerase delta subunits 1 and 4 identifed by column chromotography xref: IntAct:EBI-865140 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN [Term] id: CCO:I0007591 name: erbb1-erbb2-1 physical interaction comment: Interaction between human erbB1 and erbB2 detected by coIP xref: IntAct:EBI-875446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN [Term] id: CCO:I0007592 name: erbb1-erbb3-1 physical interaction comment: Interaction between human erbB1 and erbB3 detected by coIP xref: IntAct:EBI-875451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN [Term] id: CCO:I0007593 name: erbb1-erbb4-1 physical interaction comment: Interaction between human erbB1 and erbB4 detected by coIP xref: IntAct:EBI-875456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:I0007594 name: brca1-trrap-4 direct interaction comment: Interaction detected by far western. xref: IntAct:EBI-896511 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN [Term] id: CCO:I0007595 name: brca1-trrap-5 physical interaction comment: Interaction detected by pulldown. xref: IntAct:EBI-896576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN [Term] id: CCO:I0007596 name: brca1-trrap-7 physical interaction comment: Interaction detected by sucrose gradient. xref: IntAct:EBI-896617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001431 ! SUPT3_HUMAN relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:I0007598 name: skp2-skp1 physical interaction xref: IntAct:EBI-914687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0005940 ! Q9UC27_HUMAN [Term] id: CCO:I0007599 name: fbxw11-skp1 physical interaction xref: IntAct:EBI-914707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0005941 ! FBW1B_HUMAN [Term] id: CCO:I0007600 name: btrc-skp1-1 physical interaction xref: IntAct:EBI-914716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0007601 name: btrc-wee1 physical interaction xref: IntAct:EBI-914868 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN [Term] id: CCO:I0007602 name: fbxw11-wee1 physical interaction xref: IntAct:EBI-914887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0005941 ! FBW1B_HUMAN [Term] id: CCO:I0007603 name: eif4g2-eif4a1-2 direct interaction comment: Interaction between eIF4G2 and eIF4A1 demonstrated by NMR xref: IntAct:EBI-928036 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001699 ! IF4G2_HUMAN relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN [Term] id: CCO:I0007604 name: app-nsf-1 physical interaction comment: Interacting partners of human APP from brains samples derived from Alzheimers patients xref: IntAct:EBI-960166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0022139 ! DYN1_HUMAN relationship: has_participant CCO:B0031679 ! MBP_HUMAN relationship: has_participant CCO:B0038850 ! NSF_HUMAN relationship: has_participant CCO:B0054861 ! CRYAB_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN relationship: has_participant CCO:B0063301 ! STXB1_HUMAN [Term] id: CCO:I0007605 name: wasl-lck-1 phosphorylation comment: Phosphorylation of WASL by LCK xref: IntAct:EBI-984782 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005942 ! WASL_HUMAN [Term] id: CCO:I0007606 name: wasl-lck-2 phosphorylation comment: Phosphorylation of WASL by LCK xref: IntAct:EBI-984865 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0005942 ! WASL_HUMAN [Term] id: CCO:I0007607 name: phb-tp53-3 physical interaction comment: Coimmunoprecipitation of Prohibitin and CRM-1 protein xref: IntAct:EBI-985269 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN [Term] id: CCO:I0007608 name: tp53-phb- physical interaction comment: Coimmunoprecipitation of CRM-1 protein and Prohibitin xref: IntAct:EBI-985279 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN [Term] id: CCO:I0007609 name: ubqln4-mdk physical interaction xref: IntAct:EBI-950230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001544 ! MK_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0007610 name: ubqln4-ptn-1 physical interaction xref: IntAct:EBI-950326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0007611 name: ubqln4-stmn1 physical interaction xref: IntAct:EBI-950386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001528 ! STMN1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0007612 name: ubqln4-ywhaq physical interaction xref: IntAct:EBI-950440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0007613 name: aptx-cntrob physical interaction xref: IntAct:EBI-950638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001961 ! CNTRB_HUMAN relationship: has_participant CCO:B0005943 ! APTX_HUMAN [Term] id: CCO:I0007614 name: atn1-jag2 physical interaction xref: IntAct:EBI-950818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002245 ! JAG2_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0007615 name: atn1-jag2-1 physical interaction xref: IntAct:EBI-951004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002245 ! JAG2_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0007616 name: atn1-siah1 physical interaction xref: IntAct:EBI-951208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001946 ! SIAH1_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0007617 name: atn1-siah2 physical interaction xref: IntAct:EBI-951214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001384 ! SIAH2_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0007618 name: atn1-spag5 physical interaction xref: IntAct:EBI-951220 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002058 ! SPAG5_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0007619 name: atxn1-btg3 physical interaction xref: IntAct:EBI-951262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001778 ! BTG3_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0007620 name: atxn1-apbb1 physical interaction xref: IntAct:EBI-951526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0007621 name: atxn1-apbb1-1 physical interaction xref: IntAct:EBI-951736 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0007622 name: atxn1-ube2i physical interaction xref: IntAct:EBI-952078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0007623 name: atxn1-btg3-1 physical interaction xref: IntAct:EBI-952204 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001778 ! BTG3_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0007624 name: atxn1-dctn3 physical interaction xref: IntAct:EBI-952228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001440 ! DCTN3_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0007625 name: atxn1-gspt1 physical interaction xref: IntAct:EBI-952276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001520 ! ERF3A_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0007626 name: atxn7-tp53bp2 physical interaction xref: IntAct:EBI-952468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0007627 name: atxn7l3-sertad1 physical interaction xref: IntAct:EBI-952504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002202 ! SRTD1_HUMAN relationship: has_participant CCO:B0005946 ! Q8IY68_HUMAN [Term] id: CCO:I0007628 name: coil-actn4 physical interaction xref: IntAct:EBI-952558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:I0007629 name: gfi1-prkcabp physical interaction xref: IntAct:EBI-952774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002083 ! GFI1_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0007630 name: gfi1b-actn1 physical interaction xref: IntAct:EBI-952780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0007631 name: gfi1b-agrn physical interaction xref: IntAct:EBI-952786 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005949 ! AGRIN_HUMAN [Term] id: CCO:I0007632 name: gfi1b-becn1 physical interaction xref: IntAct:EBI-952792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005950 ! BECN1_HUMAN [Term] id: CCO:I0007633 name: gfi1b-brca1 physical interaction xref: IntAct:EBI-952798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN [Term] id: CCO:I0007634 name: gfi1b-bre physical interaction xref: IntAct:EBI-952804 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005951 ! BRE_HUMAN [Term] id: CCO:I0007635 name: gfi1b-c20orf12 physical interaction xref: IntAct:EBI-952810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005952 ! CT012_HUMAN [Term] id: CCO:I0007636 name: gfi1b-cenpb physical interaction xref: IntAct:EBI-952816 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005431 ! CENPB_HUMAN [Term] id: CCO:I0007637 name: gfi1b-cenpj physical interaction xref: IntAct:EBI-952822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005426 ! CENPJ_HUMAN [Term] id: CCO:I0007638 name: gfi1b-dkfzp586m1819 physical interaction xref: IntAct:EBI-952828 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005953 ! Q8NDD3_HUMAN [Term] id: CCO:I0007639 name: gfi1b-dtna physical interaction xref: IntAct:EBI-952834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005954 ! DTNA_HUMAN [Term] id: CCO:I0007640 name: gfi1b-efemp1 physical interaction xref: IntAct:EBI-952840 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005955 ! FBLN3_HUMAN [Term] id: CCO:I0007641 name: gfi1b-efemp2 physical interaction xref: IntAct:EBI-952846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN [Term] id: CCO:I0007642 name: gfi1b-megf6 physical interaction xref: IntAct:EBI-952852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005956 ! MEGF6_HUMAN [Term] id: CCO:I0007643 name: gfi1b-megf8 physical interaction xref: IntAct:EBI-952858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005957 ! MEGF8_HUMAN [Term] id: CCO:I0007644 name: gfi1b-egfl7 physical interaction xref: IntAct:EBI-952864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005958 ! EGFL7_HUMAN [Term] id: CCO:I0007645 name: gfi1b-fbln1 physical interaction xref: IntAct:EBI-952870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005959 ! FBLN1_HUMAN [Term] id: CCO:I0007646 name: gfi1b-grip2 physical interaction xref: IntAct:EBI-952882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005960 ! GRIP2_HUMAN [Term] id: CCO:I0007647 name: gfi1b-grn physical interaction xref: IntAct:EBI-952888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005961 ! GRN_HUMAN [Term] id: CCO:I0007648 name: gfi1b-hecw1 physical interaction xref: IntAct:EBI-952894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005962 ! HECW1_HUMAN [Term] id: CCO:I0007649 name: gfi1b-hgs physical interaction xref: IntAct:EBI-952900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0007650 name: gfi1b-hnrpk physical interaction xref: IntAct:EBI-952906 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:I0007651 name: gfi1b-hom_tes_103 physical interaction xref: IntAct:EBI-952912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005963 ! Q6P593_HUMAN [Term] id: CCO:I0007652 name: gfi1b-hspg2 physical interaction xref: IntAct:EBI-952918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005964 ! PGBM_HUMAN [Term] id: CCO:I0007653 name: gfi1b-jag2-1 physical interaction xref: IntAct:EBI-952924 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0002245 ! JAG2_HUMAN [Term] id: CCO:I0007654 name: gfi1b-begain physical interaction xref: IntAct:EBI-952936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:I0007655 name: gfi1b-anks3 physical interaction xref: IntAct:EBI-952942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005965 ! ANKS3_HUMAN [Term] id: CCO:I0007656 name: gfi1b-kif17 physical interaction xref: IntAct:EBI-952948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005966 ! KIF17_HUMAN [Term] id: CCO:I0007657 name: gfi1b-lamb1 physical interaction xref: IntAct:EBI-952954 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005967 ! LAMB1_HUMAN [Term] id: CCO:I0007658 name: gfi1b-lzts2 physical interaction xref: IntAct:EBI-952966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN [Term] id: CCO:I0007659 name: gfi1b-matr3 physical interaction xref: IntAct:EBI-952972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:I0007660 name: gfi1b-mid2 physical interaction xref: IntAct:EBI-952978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005969 ! TRIM1_HUMAN [Term] id: CCO:I0007661 name: gfi1b-mon1a physical interaction xref: IntAct:EBI-952984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005970 ! MON1A_HUMAN [Term] id: CCO:I0007662 name: gfi1b-myh14 physical interaction xref: IntAct:EBI-952990 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005971 ! MYH14_HUMAN [Term] id: CCO:I0007663 name: gfi1b-nelf physical interaction xref: IntAct:EBI-953002 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005972 ! NELF_HUMAN [Term] id: CCO:I0007664 name: gfi1b-nell1 physical interaction xref: IntAct:EBI-953008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005973 ! NELL1_HUMAN [Term] id: CCO:I0007665 name: gfi1b-nell2-1 physical interaction xref: IntAct:EBI-953014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005427 ! NELL2_HUMAN [Term] id: CCO:I0007666 name: gfi1b-notch1 physical interaction xref: IntAct:EBI-953020 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN [Term] id: CCO:I0007667 name: gfi1b-pde4dip physical interaction xref: IntAct:EBI-953026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005975 ! Q5TB27_HUMAN [Term] id: CCO:I0007668 name: gfi1b-enh physical interaction xref: IntAct:EBI-953032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005976 ! PDLI5_HUMAN [Term] id: CCO:I0007669 name: gfi1b-pdzk4 physical interaction xref: IntAct:EBI-953038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005977 ! PDZD4_HUMAN [Term] id: CCO:I0007670 name: gfi1b-phc2 physical interaction xref: IntAct:EBI-953044 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005978 ! PHC2_HUMAN [Term] id: CCO:I0007671 name: gfi1b-prkcabp physical interaction xref: IntAct:EBI-953050 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0007672 name: gfi1b-rab11fip4 physical interaction xref: IntAct:EBI-953056 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005979 ! RFIP4_HUMAN [Term] id: CCO:I0007673 name: gfi1b-rchy1 physical interaction xref: IntAct:EBI-953062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005980 ! ZN363_HUMAN [Term] id: CCO:I0007674 name: gfi1b-rfp physical interaction xref: IntAct:EBI-953068 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005981 ! TRI27_HUMAN [Term] id: CCO:I0007675 name: gfi1b-rint1 physical interaction xref: IntAct:EBI-953074 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0001909 ! RINT1_HUMAN [Term] id: CCO:I0007676 name: gfi1b-rnf31 physical interaction xref: IntAct:EBI-953080 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005982 ! RNF31_HUMAN [Term] id: CCO:I0007678 name: gfi1b-taf1 physical interaction xref: IntAct:EBI-953092 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN [Term] id: CCO:I0007679 name: gfi1b-tmf1 physical interaction xref: IntAct:EBI-953104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005984 ! TMF1_HUMAN [Term] id: CCO:I0007680 name: gfi1b-trip6 physical interaction xref: IntAct:EBI-953110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:I0007681 name: gfi1b-vsnl1 physical interaction xref: IntAct:EBI-953122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005986 ! VISL1_HUMAN [Term] id: CCO:I0007682 name: gfi1b-actn1-1 physical interaction xref: IntAct:EBI-953134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0007683 name: gfi1b-aes physical interaction xref: IntAct:EBI-953140 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005987 ! AES_HUMAN [Term] id: CCO:I0007684 name: gfi1b-atxn2 physical interaction xref: IntAct:EBI-953146 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0007685 name: gfi1b-dnaja3 physical interaction xref: IntAct:EBI-953152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0007686 name: gfi1b-efemp1-1 physical interaction xref: IntAct:EBI-953158 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005955 ! FBLN3_HUMAN [Term] id: CCO:I0007687 name: gfi1b-efemp2-1 physical interaction xref: IntAct:EBI-953164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN [Term] id: CCO:I0007688 name: gfi1b-fbln5 physical interaction xref: IntAct:EBI-953170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005989 ! FBLN5_HUMAN [Term] id: CCO:I0007689 name: gfi1b-jub physical interaction xref: IntAct:EBI-953176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0026254 ! JUB_HUMAN [Term] id: CCO:I0007690 name: gfi1b-prkcabp-1 physical interaction xref: IntAct:EBI-953182 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0007691 name: gfi1b-psma3 physical interaction xref: IntAct:EBI-953188 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:I0007692 name: gfi1b-traf1 physical interaction xref: IntAct:EBI-953194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0007693 name: gfi1b-trip6-1 physical interaction xref: IntAct:EBI-953200 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:I0007694 name: gfi1b-txndc11 physical interaction xref: IntAct:EBI-953206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0005993 ! TXD11_HUMAN [Term] id: CCO:I0007695 name: sacs-actn4 physical interaction xref: IntAct:EBI-953488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0005994 ! SACS_HUMAN [Term] id: CCO:I0007696 name: atm-cabl-1 physical interaction comment: Interaction between human ATM and c-Abl detected by coIP xref: IntAct:EBI-1005980 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:I0007697 name: atm-pin2_trf1-1 physical interaction comment: Interaction between human ATM and Pin2/TRF1 detected by coIP xref: IntAct:EBI-1006035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:I0007698 name: pin2_trf1-atm-2 physical interaction comment: Interaction between human Pin2/TRF1 and ATM detected by coIP xref: IntAct:EBI-1006045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN [Term] id: CCO:I0007699 name: ctnnb1-tcf7l2-2 physical interaction xref: IntAct:EBI-1017678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007700 name: ctnnb1-tcf7l2-3 physical interaction xref: IntAct:EBI-1017698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:I0007701 name: ctnnb1-tcf7l2-4 physical interaction xref: IntAct:EBI-1017717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0007702 name: ctnnb1-tcf7l2-5 physical interaction xref: IntAct:EBI-1017745 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:I0007703 name: ctnnb1-tcf7l2-6 physical interaction xref: IntAct:EBI-1017766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:I0007704 name: jup-psen1-6 physical interaction xref: IntAct:EBI-1017821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007705 name: tcf7l2-ctnnb1-3 physical interaction xref: IntAct:EBI-1017848 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0007706 name: jup-psen1-7 physical interaction xref: IntAct:EBI-1018704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0007707 name: tp53-nfya physical interaction xref: IntAct:EBI-1025792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0007708 name: hras-rasa1-1 direct interaction comment: Ras-rasgap complex xref: IntAct:EBI-1026524 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN [Term] id: CCO:I0007709 name: bmp2-bmpr1a-2 direct interaction comment: Structural refinement of the complex of bone morphogenetic protein 2 and its type ia receptor xref: IntAct:EBI-1038504 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0005437 ! BMR1A_HUMAN [Term] id: CCO:I0007710 name: tap1-b2m physical interaction xref: IntAct:EBI-1168086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001563 ! CALR_HUMAN relationship: has_participant CCO:B0005889 ! TAP1_HUMAN relationship: has_participant CCO:B0042031 ! PDIA3_HUMAN [Term] id: CCO:I0007711 name: wapl-cspg6-4 physical interaction xref: IntAct:EBI-1175658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007712 name: wapl-cspg6-5 physical interaction xref: IntAct:EBI-1175670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007713 name: wapl-cspg6-6 physical interaction xref: IntAct:EBI-1175685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007714 name: wapl-cspg6-7 physical interaction xref: IntAct:EBI-1175700 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007715 name: wapl-cspg6-9 physical interaction xref: IntAct:EBI-1175727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0005721 ! WAPL_HUMAN [Term] id: CCO:I0007716 name: cul4b-ddb1-1 physical interaction xref: IntAct:EBI-1176157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN relationship: has_participant CCO:B0005658 ! DDB2_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0005687 ! GRWD1_HUMAN relationship: has_participant CCO:B0005688 ! WDR82_HUMAN relationship: has_participant CCO:B0005689 ! WDR26_HUMAN relationship: has_participant CCO:B0005996 ! WDR57_HUMAN relationship: has_participant CCO:B0005997 ! WDR76_HUMAN relationship: has_participant CCO:B0005998 ! WD51B_HUMAN relationship: has_participant CCO:B0005999 ! WDR61_HUMAN relationship: has_participant CCO:B0006000 ! WDR5B_HUMAN relationship: has_participant CCO:B0006001 ! RFWD2_HUMAN [Term] id: CCO:I0007717 name: cul4b-wdr5 physical interaction xref: IntAct:EBI-1176554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0005615 ! WDR5_HUMAN [Term] id: CCO:I0007718 name: stat5b-nmi-4 physical interaction comment: Interaction between human Stat5b and Nmi detected by Y2H xref: IntAct:EBI-1186248 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007719 name: sds3-brms1 physical interaction comment: BRMS1 coimmunoprecipitates with SDS3 in COS7 cell lysate xref: IntAct:EBI-1200021 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005694 ! SDS3_HUMAN [Term] id: CCO:I0007720 name: dnajb6-brms1 physical interaction comment: BRMS1 coimmunoprecipitates with MRJ (DNAJB6) in COS7 cell lysate xref: IntAct:EBI-1200029 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005696 ! DNJB6_HUMAN [Term] id: CCO:I0007721 name: nmi-brms1 physical interaction comment: BRMS1 coimmunoprecipitates with NMI in COS7 cell lysate xref: IntAct:EBI-1200215 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007722 name: smarce1-brms1 physical interaction comment: BRMS1 coimmunoprecipitates with BAF57 (SMARCE1) in COS7 cell lysate xref: IntAct:EBI-1200228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN [Term] id: CCO:I0007723 name: brca2-rad51-4 physical interaction comment: Interaction of deletion constructs of BRCA2 with RAD51 determined by GST-pull down. xref: IntAct:EBI-298264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007724 name: brap-hras physical interaction comment: Interaction of BRAP with H-Ras demonstrated by GST pull down xref: IntAct:EBI-350144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:I0007725 name: eef1b1-rps3a-1 physical interaction comment: interaction detected by chromatography. xref: IntAct:EBI-354614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0005738 ! VDAC3_HUMAN relationship: has_participant CCO:B0005752 ! EF1B_HUMAN relationship: has_participant CCO:B0005756 ! DHRS2_HUMAN relationship: has_participant CCO:B0005765 ! VDAC1_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0005774 ! ROA1_HUMAN relationship: has_participant CCO:B0005777 ! VDAC2_HUMAN [Term] id: CCO:I0007726 name: h3fa-suv39h1 physical interaction xref: IntAct:EBI-360204 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005221 ! H31_HUMAN [Term] id: CCO:I0007727 name: app-apbb1-5 physical interaction comment: in vitro co-ip of beta-APP cytoplasmic domain and fe65 xref: IntAct:EBI-371450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007728 name: lats1-zyx-4 physical interaction comment: Interaction betwen human LATS1 and ZYX confirmed by co-immunoprecipitation xref: IntAct:EBI-444259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007729 name: lats1-cdc2-2 physical interaction comment: Interaction between human LATS1 and CDC2 demonstrated by Y2H xref: IntAct:EBI-444369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:I0007730 name: lats1-limk1-4 physical interaction comment: Interaction of human LATS1 and LIMK1, domains identified using GST-pull down xref: IntAct:EBI-444472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN [Term] id: CCO:I0007731 name: skp2-cks1-1 physical interaction comment: Interaction between SKP2 and CKS1 demonstrated in vitro xref: IntAct:EBI-456369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:I0007732 name: skp2-cks1-2 physical interaction comment: Interaction between SKP2 and CKS1 demonstrated in vitro xref: IntAct:EBI-456385 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:I0007733 name: skp2-cks1-4 physical interaction comment: Formation of SCF-SKP2 demonstrated in vitro xref: IntAct:EBI-456401 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0005491 ! RBX1_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0007734 name: taf1l-tbp-1 physical interaction comment: TAF1l interacts with human TBP, as detected by Y2H. xref: IntAct:EBI-475867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001959 ! TAF1L_HUMAN relationship: has_participant CCO:B0005481 ! TBP_HUMAN [Term] id: CCO:I0007735 name: trib1-map2k1-1 physical interaction comment: Interaction detected by co-immunoprecipitation xref: IntAct:EBI-492579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0006002 ! TRIB1_HUMAN [Term] id: CCO:I0007736 name: trib3-map2k1-2 physical interaction comment: Interaction detected by co-immunoprecipitation xref: IntAct:EBI-492595 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN [Term] id: CCO:I0007737 name: hd-p53-3 physical interaction comment: in vivo GST-pull down : bait = huntingtin poly(Q) region ; prey = P53 xref: IntAct:EBI-493052 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0007738 name: hd-p53-4 physical interaction comment: in vivo GST-pull down : bait = huntingtin poly(Q) region ; prey = P53 xref: IntAct:EBI-493068 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0007739 name: cdk4-ccnd1-4 physical interaction comment: in vitro co-IP: bait = cyclin D1, prey = cdk4 xref: IntAct:EBI-519455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:I0007740 name: raf1-hras physical interaction comment: Y2H: bait = C-Raf ,prey = HA-Ras-C-Ha-ras p21 protein xref: IntAct:EBI-537202 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0007741 name: cdn1b-kpna5-4 physical interaction comment: pull-down: bait = p27 KIP1 peptide, prey= importin alpha 5 xref: IntAct:EBI-540655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005697 ! IMA5_HUMAN [Term] id: CCO:I0007742 name: cdn1b-ywhab-1 physical interaction comment: pull-down: bait = phosphorylated thr127 p27 KIP1 peptide, prey= 14-3-3 beta xref: IntAct:EBI-540682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN [Term] id: CCO:I0007743 name: cdn1b-ywhae-1 physical interaction comment: pull-down: bait = phosphorylated thr127 p27 KIP1 peptide, prey = 14-3-3 epsilon xref: IntAct:EBI-540704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN [Term] id: CCO:I0007744 name: cdn1b-ywhag-1 physical interaction comment: pull-down: bait = phosphorylated thr127 p27 KIP1 peptide, prey = 14-3-3 gamma xref: IntAct:EBI-540723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005489 ! 1433G_HUMAN [Term] id: CCO:I0007745 name: daxx-ar-4 physical interaction comment: Interaction of DAXX and AR detected by CoIP. xref: IntAct:EBI-608217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:I0007746 name: daxx-ar-5 physical interaction comment: Interaction of DAXX and AR (sumoylated) detected by CoIP. xref: IntAct:EBI-608277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:I0007747 name: gnai1-gpsm2-2 physical interaction xref: IntAct:EBI-618721 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN [Term] id: CCO:I0007748 name: c9orf76-blm-1 physical interaction comment: coimmunoprecipitation: bait = BLAP75, preys = BLM, TOPOIIIalpha, RPA70, RPA32 xref: IntAct:EBI-621416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0001753 ! TOP3A_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:I0007749 name: blm-c9orf76-1 physical interaction comment: coimmunoprecipitation: bait = BLM, preys = BLAP75, TOPOIIIalpha, RPA70, RPA32, RPA14 xref: IntAct:EBI-621422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0001753 ! TOP3A_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005501 ! RFA3_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:I0007750 name: gpsm2-numa1-4 physical interaction xref: IntAct:EBI-624047 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0007751 name: abl1-sorbs-1 physical interaction comment: Interaction between SORB1 and ABL1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-624110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:I0007752 name: hcfc1-creb3-1 physical interaction comment: Cell-based recruitment assay to determine interaction between hcfc1 and creb3 and effects of mutations within hcfc1 upon this interaction. xref: IntAct:EBI-624998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN [Term] id: CCO:I0007753 name: mdm2-npm1-1 physical interaction comment: coIP: bait = HDM2, prey = NPM xref: IntAct:EBI-626277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN [Term] id: CCO:I0007754 name: hcfc1-zf-4 physical interaction comment: GST pull-down of interaction between hcfc1 and zf and the effect of p134s mutation in hcfc1 xref: IntAct:EBI-633114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0007755 name: hcfc1-zf-5 physical interaction comment: Mammalian two-hybrid assay of interaction between hcfc1 and zf xref: IntAct:EBI-633135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0007756 name: brg1-baf250a-2 physical interaction comment: coIP: bait = brg1, preys = baf250a, baf170, baf155, baf60a, baf53, snf5, actin xref: IntAct:EBI-638024 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0007757 name: pten-mast3-1 physical interaction comment: Interaction between human PTEN and Mast3 identified by GST pulldown xref: IntAct:EBI-696276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0005499 ! MAST3_HUMAN [Term] id: CCO:I0007758 name: actn2-ttn-2 physical interaction comment: Detection of alpha-actinin 2 and Titin binding domains by yeast two hybrid. xref: IntAct:EBI-698577 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0007759 name: wrn-rpa1-1 physical interaction comment: In vitro co-IP: bait = WRN, prey = human Replication Protein A RPA (70kDa subunit) xref: IntAct:EBI-707108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007760 name: wrn-rpa1-5 physical interaction comment: ELISA: bait =WRN, probe = human Replication Protein A RPA70 (70kDa subunit) xref: IntAct:EBI-707234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007761 name: wrn-rpa1-6 physical interaction comment: ELISA: bait=WRN, probe = human Replication Protein A RPA70 (70kDa subunit) xref: IntAct:EBI-707245 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0007762 name: blm-rpa1-1 physical interaction comment: ELISA: bait =BLM, probe = human Replication Protein A RPA70 (70kDa subunit) xref: IntAct:EBI-707256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0007763 name: blm-rpa1-2 physical interaction comment: ELISA: bait=BLM, probe = human Replication Protein A RPA70 (70kDa subunit) xref: IntAct:EBI-707269 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0007764 name: bak-bax-1 physical interaction comment: Interaction of BAK and BAX identified by coimmunoprecipitation xref: IntAct:EBI-707374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0005420 ! BAK_HUMAN [Term] id: CCO:I0007765 name: bim-bcl2-2 direct interaction comment: Interaction of BIM with BCL-2 by biacore xref: IntAct:EBI-707839 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0006003 ! BIM_HUMAN [Term] id: CCO:I0007766 name: bbc3-bcl2-4 direct interaction comment: Interaction of BBC3 with BCL-2 by biacore xref: IntAct:EBI-707957 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN [Term] id: CCO:I0007767 name: bad-bcl2-3 direct interaction comment: Interaction of BAD with BCL-2 by biacore xref: IntAct:EBI-708078 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:I0007768 name: blm-terf2-6 direct interaction comment: In vitro Co-IP: bait= TRF2 (TERF2), prey = BLM xref: IntAct:EBI-711071 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0007769 name: bcl6-hdac5 physical interaction comment: Coimuunoprecipitation of the BCL6 immunocomplex. xref: IntAct:EBI-765648 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001352 ! E2F3_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0002222 ! HDAC9_HUMAN relationship: has_participant CCO:B0002244 ! HDAC5_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005849 ! KI13B_HUMAN relationship: has_participant CCO:B0005934 ! WNK4_HUMAN relationship: has_participant CCO:B0005935 ! PKCB1_HUMAN relationship: has_participant CCO:B0006004 ! CSMD1_HUMAN relationship: has_participant CCO:B0006005 ! LSM1_HUMAN relationship: has_participant CCO:B0006006 ! EHMT1_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0006009 ! OSBL1_HUMAN relationship: has_participant CCO:B0006010 ! TNR8_HUMAN relationship: has_participant CCO:B0006011 ! TYY1_HUMAN relationship: has_participant CCO:B0006012 ! 4ET_HUMAN relationship: has_participant CCO:B0006013 ! DDX6_HUMAN relationship: has_participant CCO:B0006014 ! ZN443_HUMAN relationship: has_participant CCO:B0006015 ! E2AK3_HUMAN relationship: has_participant CCO:B0006016 ! ATF7_HUMAN relationship: has_participant CCO:B0006017 ! SPTC2_HUMAN relationship: has_participant CCO:B0006018 ! SENP7_HUMAN relationship: has_participant CCO:B0006019 ! LPP3_HUMAN relationship: has_participant CCO:B0006020 ! BC11A_HUMAN relationship: has_participant CCO:B0006021 ! IDI2_HUMAN relationship: has_participant CCO:B0006022 ! PCDH9_HUMAN relationship: has_participant CCO:B0006023 ! T3JAM_HUMAN relationship: has_participant CCO:B0006024 ! EPHB6_HUMAN relationship: has_participant CCO:B0006025 ! WDR35_HUMAN relationship: has_participant CCO:B0006026 ! RNC_HUMAN relationship: has_participant CCO:B0006027 ! ELF1_HUMAN relationship: has_participant CCO:B0006028 ! DYH9_HUMAN relationship: has_participant CCO:B0006029 ! PANX3_HUMAN relationship: has_participant CCO:B0006030 ! COE1_HUMAN relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0006033 ! ARNT2_HUMAN relationship: has_participant CCO:B0006034 ! JIP3_HUMAN relationship: has_participant CCO:B0006035 ! PR285_HUMAN relationship: has_participant CCO:B0006036 ! ERCC5_HUMAN relationship: has_participant CCO:B0006037 ! PAR12_HUMAN relationship: has_participant CCO:B0006038 ! NKRF_HUMAN relationship: has_participant CCO:B0006039 ! SMO_HUMAN relationship: has_participant CCO:B0006040 ! OLA1_HUMAN relationship: has_participant CCO:B0006041 ! TBL1R_HUMAN relationship: has_participant CCO:B0006042 ! MINT_HUMAN relationship: has_participant CCO:B0006044 ! CAC1A_HUMAN relationship: has_participant CCO:B0006046 ! SAE1_HUMAN relationship: has_participant CCO:B0006047 ! WNT16_HUMAN relationship: has_participant CCO:B0006048 ! HSF4_HUMAN relationship: has_participant CCO:B0006049 ! PO2F3_HUMAN relationship: has_participant CCO:B0006050 ! UTP6_HUMAN relationship: has_participant CCO:B0006051 ! JHD1A_HUMAN relationship: has_participant CCO:B0006052 ! MTMR6_HUMAN relationship: has_participant CCO:B0043865 ! MLL4_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN relationship: has_participant CCO:B0043867 ! LPAR4_HUMAN [Term] id: CCO:I0007770 name: ruvbl1-ruvbl2 physical interaction comment: MudPit analysis isolates proteins associated with Ruvbl1. xref: IntAct:EBI-769253 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005367 ! ARP6_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0061989 ! IN80E_HUMAN relationship: has_participant CCO:B0061990 ! IN80B_HUMAN relationship: has_participant CCO:B0061991 ! INO80_HUMAN [Term] id: CCO:I0007771 name: ruvbl2-ruvbl1 physical interaction comment: MudPit analysis isolates proteins associated with Ruvbl2. xref: IntAct:EBI-769446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005367 ! ARP6_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005371 ! EPC2_HUMAN relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0061989 ! IN80E_HUMAN relationship: has_participant CCO:B0061990 ! IN80B_HUMAN relationship: has_participant CCO:B0061991 ! INO80_HUMAN [Term] id: CCO:I0007772 name: mrgbp-ruvbl1 physical interaction comment: MudPit analysis isolates proteins associated with MRGBP xref: IntAct:EBI-769473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005371 ! EPC2_HUMAN [Term] id: CCO:I0007773 name: znf-ruvbl physical interaction comment: MudPit analysis isolates proteins associated with ZNF xref: IntAct:EBI-769555 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:I0007774 name: znhit4-ruvbl-1 physical interaction comment: MudPit analysis isolates proteins associated with ZNHIT4 xref: IntAct:EBI-769582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0061990 ! IN80B_HUMAN [Term] id: CCO:I0007775 name: actr8-ruvbl physical interaction comment: MudPit analysis isolates proteins associated with ACTR8 xref: IntAct:EBI-769657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0006058 ! ARP8_HUMAN [Term] id: CCO:I0007777 name: mcrs1-ruvbl physical interaction comment: MudPit analysis isolates proteins associated with MCRS1 xref: IntAct:EBI-769695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002036 ! MCRS1_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:I0007778 name: fj90652-ruvbl-1 physical interaction comment: MudPit analysis isolates proteins associated with FJ90652 xref: IntAct:EBI-769712 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0061989 ! IN80E_HUMAN [Term] id: CCO:I0007779 name: flj20309-ruvbl-2 physical interaction comment: MudPit analysis isolates proteins associated with FLJ20309 xref: IntAct:EBI-769729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0061992 ! IN80D_HUMAN [Term] id: CCO:I0007780 name: mrgbp-ruvbl1-2 physical interaction comment: Affinity chromotography analysis isolates proteins associated with MRGBP xref: IntAct:EBI-769870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:I0007781 name: tcfl1-ruvbl1-3 physical interaction comment: Affinity chromotography analysis isolates proteins associated with TCFL1 xref: IntAct:EBI-769893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:I0007782 name: znf-ruvbl1 physical interaction comment: Affinity chromotography analysis isolates proteins associated with ZNF xref: IntAct:EBI-769907 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:I0007783 name: dapk3-daxx-3 physical interaction comment: Interaction of DAPK3 with DAXX xref: IntAct:EBI-77349 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0006060 ! DAPK3_HUMAN [Term] id: CCO:I0007784 name: tgfb1-tgfb2-bapp-2 physical interaction comment: Interaction between transforming growth factors beta 1 and beta 2 and beta amyloid precursor protein xref: IntAct:EBI-779662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0007785 name: hrmt1l2-ilf3-3 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0005713 ! ANM1_HUMAN [Term] id: CCO:I0007786 name: top1-2 physical interaction comment: Co-immunoprecipitation analysis reveals proteins interacting with Topoisomerase 1 xref: IntAct:EBI-876685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN relationship: has_participant CCO:B0005587 ! TOP1_HUMAN relationship: has_participant CCO:B0005725 ! ROA2_HUMAN relationship: has_participant CCO:B0005774 ! ROA1_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005805 ! DDX21_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0020752 ! PRP8_HUMAN relationship: has_participant CCO:B0020984 ! U520_HUMAN relationship: has_participant CCO:B0056099 ! ELAV1_HUMAN relationship: has_participant CCO:B0062841 ! DDX17_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN relationship: has_participant CCO:B0063188 ! H12_HUMAN relationship: has_participant CCO:B0063189 ! RU2A_HUMAN [Term] id: CCO:I0007787 name: ep300-nap1l1-4 physical interaction xref: IntAct:EBI-923630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0007788 name: ep300-nap1l1-5 physical interaction xref: IntAct:EBI-923635 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0007789 name: disc1-atf5-7 physical interaction comment: Mammalian 2 hybrid analysis reveals interaction between the DISC1 protein and ATF5 protein xref: IntAct:EBI-930706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0007790 name: cdc73-ctnnb1-3 physical interaction xref: IntAct:EBI-932426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007791 name: cdc73-ctnnb1-6 physical interaction xref: IntAct:EBI-932465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:I0007792 name: cdc73-ctnnb1-7 physical interaction xref: IntAct:EBI-932479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0006062 ! PYGO2_HUMAN [Term] id: CCO:I0007793 name: tfap2c-cited2-1 physical interaction comment: Interaction between human TFAP2C and CITED2 detected by Y2H xref: IntAct:EBI-937799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005377 ! AP2C_HUMAN [Term] id: CCO:I0007794 name: sept5-sept11-2 direct interaction comment: Affinity chromatography analysis reveals interaction between SEPT5 protein and SEPT11 protein xref: IntAct:EBI-958153 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002169 ! SEP11_HUMAN [Term] id: CCO:I0007795 name: bcl10-akt1-1 physical interaction comment: Interaction between BCL10 and Ak1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-958921 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:I0007796 name: bcl10-akt1-2 physical interaction comment: Interaction between BCL10 and Ak1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-958936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:I0007797 name: bcl10-bcl3-1 physical interaction comment: Interaction between BCL3 and BCL10 demonstrated by coimmunoprecipitation xref: IntAct:EBI-959017 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN [Term] id: CCO:I0007798 name: bcl10-bcl3-2 physical interaction comment: Interaction between BCL3 and BCL10 demonstrated by coimmunoprecipitation xref: IntAct:EBI-959026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN [Term] id: CCO:I0007799 name: st5-abl1-1 physical interaction xref: IntAct:EBI-962642 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0006063 ! ST5_HUMAN [Term] id: CCO:I0007800 name: hspcb-chk1-1 physical interaction comment: Interaction between HSPCB and CHEK1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-974545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0007801 name: acaca-brca1 physical interaction xref: IntAct:EBI-978623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:I0007802 name: phb-tp53-1 colocalization comment: Colocalisation of Prohibitin and p53 protein xref: IntAct:EBI-985186 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN [Term] id: CCO:I0007803 name: tcf7l2-ctnnb1-1 physical interaction xref: IntAct:EBI-989564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:I0007804 name: tcf7l2-ctnnb1-5 physical interaction xref: IntAct:EBI-989727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0007805 name: tcf7l2-ctnnb1-6 physical interaction xref: IntAct:EBI-989742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0007806 name: jup-tcf7l2 physical interaction xref: IntAct:EBI-989938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:I0007807 name: jup-psen1-5 physical interaction xref: IntAct:EBI-990166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005684 ! PLAK_HUMAN [Term] id: CCO:I0007808 name: ubp7-daxx-7 physical interaction xref: IntAct:EBI-992660 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007809 name: ubp7-daxx-8 physical interaction xref: IntAct:EBI-992896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007810 name: ubp7-daxx-9 physical interaction xref: IntAct:EBI-992993 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007811 name: mdm2-daxx-2 physical interaction xref: IntAct:EBI-993197 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN [Term] id: CCO:I0007812 name: usp7-hausp physical interaction xref: IntAct:EBI-993218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007813 name: ahr-aip-2 physical interaction xref: IntAct:EBI-993258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0005380 ! AIP_HUMAN [Term] id: CCO:I0007814 name: cdc27-nek2-1 physical interaction xref: IntAct:EBI-994928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001572 ! CDC27_HUMAN relationship: has_participant CCO:B0001654 ! NEK2_HUMAN [Term] id: CCO:I0007815 name: usp7-mdm2-4 direct interaction xref: IntAct:EBI-997256 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007816 name: spbc24-spbc25-5 colocalization comment: colocalization of hSpc24 and hSpc25 by immunofluorescence microscopy. xref: IntAct:EBI-1000369 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0007817 name: erbb2-egfr-4 physical interaction xref: IntAct:EBI-1001015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN [Term] id: CCO:I0007818 name: zwint_kntc2_1 physical interaction comment: coIP; bait=zwint, preys=c20orf172, casc5, cetn3, kntc2, mis12, pmf1 and spbc24 xref: IntAct:EBI-1001131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002122 ! MIS12_HUMAN relationship: has_participant CCO:B0002134 ! DSN1_HUMAN relationship: has_participant CCO:B0006064 ! CASC5_HUMAN [Term] id: CCO:I0007819 name: zw10_zwilch_1 physical interaction comment: coIP; bait=zw10, preys=c19orf25, kntc1, rint1 and zwilch xref: IntAct:EBI-1001216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001645 ! KNTC1_HUMAN relationship: has_participant CCO:B0001909 ! RINT1_HUMAN relationship: has_participant CCO:B0006066 ! CS025_HUMAN [Term] id: CCO:I0007820 name: zwint_zw10_1 physical interaction comment: coIP; bait=zwint, prey=zw10 xref: IntAct:EBI-1001272 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN [Term] id: CCO:I0007821 name: mcm7-smc1-1 direct interaction comment: Interaction between human MCM7 and Smc1 detected by coIP xref: IntAct:EBI-1004682 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:I0007822 name: stmn1-cdkn1b physical interaction xref: IntAct:EBI-1006412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001528 ! STMN1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007823 name: hnrpd-ube2i physical interaction xref: IntAct:EBI-1024437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005686 ! HNRPD_HUMAN [Term] id: CCO:I0007824 name: tp53-nfya-1 physical interaction xref: IntAct:EBI-1025803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0007825 name: ccna2-cdk2-1 physical interaction comment: P27(kip1)/cyclin a/cdk2 complex xref: IntAct:EBI-1026119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN [Term] id: CCO:I0007826 name: tgfb3-tgfbr2-1 direct interaction comment: Crystal structure of the human tgf-beta type ii receptor extracellular domain in complex with tgf-beta3 xref: IntAct:EBI-1033040 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0005542 ! TGFR2_HUMAN [Term] id: CCO:I0007827 name: fgf10-fgfr2-1 direct interaction comment: Crystal structure analysis of the fgf10-fgfr2b complex xref: IntAct:EBI-1035715 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0005381 ! FGFR2_HUMAN [Term] id: CCO:I0007828 name: cdk5-cdk5r1-1 direct interaction comment: Structural mechanism for the inhibition of cdk5-p25 by roscovitine, aloisine and indirubin. xref: IntAct:EBI-1041602 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN [Term] id: CCO:I0007829 name: cdk5-cdk5r1-2 direct interaction comment: Structural mechanism for the inhibition of cdk5-p25 by roscovitine, aloisine and indirubin. xref: IntAct:EBI-1041613 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN [Term] id: CCO:I0007830 name: cdk5-cdk5r1-3 direct interaction comment: Structural mechanism for the inhibition of cd5-p25 from the roscovitine, aloisine and indirubin. xref: IntAct:EBI-1041624 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN [Term] id: CCO:I0007831 name: rin1-hras-1 physical interaction comment: Interaction between Rin1 and H-Ras identified by coimmunoprecipitation xref: IntAct:EBI-1102869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0007832 name: rin1-hras-2 physical interaction comment: Interaction between Rin1 and H-Ras identified by coimmunoprecipitation xref: IntAct:EBI-1102880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0007833 name: rin1-hras-4 physical interaction comment: Interaction between Rin1 and H-Ras identified by yeast 2-hybrid xref: IntAct:EBI-1102914 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN [Term] id: CCO:I0007834 name: raf1-hras-4 physical interaction comment: Interaction between Raf1 and H-Ras identified by yeast 2-hybrid xref: IntAct:EBI-1102923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0007835 name: tp53-fbxo11-1 physical interaction comment: Interaction between p53 and FBX011 identified by pulldown xref: IntAct:EBI-1167834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005332 ! FBX11_HUMAN [Term] id: CCO:I0007836 name: cftr-ebp-2 physical interaction xref: IntAct:EBI-1171716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001418 ! DNJA2_HUMAN relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN relationship: has_participant CCO:B0025069 ! NHRF2_HUMAN relationship: has_participant CCO:B0025071 ! NHERF_HUMAN relationship: has_participant CCO:B0054618 ! PDCD6_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN relationship: has_participant CCO:B0062985 ! PIMT_HUMAN relationship: has_participant CCO:B0062988 ! COPB_HUMAN relationship: has_participant CCO:B0062989 ! LMNA_HUMAN relationship: has_participant CCO:B0063054 ! TPM3_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN relationship: has_participant CCO:B0063206 ! HSP77_HUMAN relationship: has_participant CCO:B0063208 ! SNX4_HUMAN relationship: has_participant CCO:B0063211 ! SQRD_HUMAN relationship: has_participant CCO:B0063287 ! G8_HUMAN relationship: has_participant CCO:B0063289 ! CH055_HUMAN relationship: has_participant CCO:B0063313 ! ATX2L_HUMAN relationship: has_participant CCO:B0063346 ! CAPR1_HUMAN relationship: has_participant CCO:B0063347 ! LMO7_HUMAN [Term] id: CCO:I0007837 name: qsk-ywhaz-2 physical interaction comment: Interaction between 14-3-3Z , QSK and SNF1LK identified by pulldown xref: IntAct:EBI-1181817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0005229 ! MARK3_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:I0007838 name: msh2-msh6-2 physical interaction comment: Mutations in hMSH2 affect the binding of hMSH2-hMSH6 hetrodimers to mismatches xref: IntAct:EBI-1187734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN [Term] id: CCO:I0007839 name: brca1-brap-2 physical interaction comment: Interaction between BRCA1 and BRAP confirmed by GST pull-down xref: IntAct:EBI-349963 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:I0007840 name: kpna-bcra1 physical interaction comment: Interaction between BRCA1 and importin-alpha2 confirmed by GST pull-down xref: IntAct:EBI-350128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001657 ! IMA2_HUMAN [Term] id: CCO:I0007841 name: bcra1-kpna2 physical interaction comment: Importin alpha-2 binds to the nuclear localisation signal of BRCA1 confirmed by GST pull down xref: IntAct:EBI-350135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001657 ! IMA2_HUMAN [Term] id: CCO:I0007842 name: daxx-slc2a4-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-367160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005473 ! GTR4_HUMAN [Term] id: CCO:I0007843 name: daxx-slc2a4-2 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-367165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005473 ! GTR4_HUMAN [Term] id: CCO:I0007844 name: stau-dhx9-1 physical interaction comment: Characterization of Staufen 1 ribonucleoprotein complexes xref: IntAct:EBI-443480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001754 ! TBB3_HUMAN relationship: has_participant CCO:B0005483 ! STAU1_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0055717 ! RL6_HUMAN [Term] id: CCO:I0007845 name: ywhaz-egfr-2 colocalization comment: 14-3-3 zeta colocalize with EGFR at the plasma membrane after EGF stimulation xref: IntAct:EBI-446474 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0007846 name: skp2-cks1-3 physical interaction comment: Interaction between SKP2 and CKS1 demonstrated in vitro xref: IntAct:EBI-456394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN [Term] id: CCO:I0007847 name: sirt2-pcaf-3 physical interaction comment: Interaction between SIRT2 and PCAF detected by in vitro binding assay. xref: IntAct:EBI-477610 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN [Term] id: CCO:I0007848 name: orc1-rps27a-1 physical interaction comment: Ubiquitylation of ORC1 xref: IntAct:EBI-492377 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN [Term] id: CCO:I0007849 name: hd-p53-1 physical interaction comment: p53 found in purified huntingtin poly(Q) aggregates xref: IntAct:EBI-492984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0007850 name: h2afx-mre11a-1 colocalization xref: IntAct:EBI-494901 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001526 ! H2AX_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN [Term] id: CCO:I0007851 name: h2afx-nbs1-3 physical interaction xref: IntAct:EBI-495031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0007852 name: h2afx-brca1-1 physical interaction xref: IntAct:EBI-495228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001526 ! H2AX_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN [Term] id: CCO:I0007853 name: cdkn1a-ccne1-6 physical interaction comment: GST pull down : bait=p21-CIP1, prey = cyclin E1, prey = cdk2 xref: IntAct:EBI-519772 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0007854 name: cdkn1a-ccnd1-2 physical interaction comment: GST pull down : bait=p21-CIP1, prey = cyclin D, prey = cdk4 xref: IntAct:EBI-519780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0007855 name: cdkn1a-ccna1-1 physical interaction comment: GST pull down : bait=p21-CIP1, prey = cyclin A1, prey = cdk2 xref: IntAct:EBI-519817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN [Term] id: CCO:I0007856 name: cdkn1a-ccne1-7 physical interaction comment: GST pull down : bait=p21-CIP1, prey = cyclin E1 xref: IntAct:EBI-519832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0007857 name: cdkn1a-cdk2-2 physical interaction comment: GST pull down : bait=p21-CIP1, prey = cdk2 xref: IntAct:EBI-519842 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:I0007858 name: dapk-erk-1 physical interaction comment: Directed yeast-2-hybrid reveals interaction between death-associated protein kinase 1protein and the mitogen-activated protein kinase 3 protein xref: IntAct:EBI-525597 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0005482 ! DAPK1_HUMAN [Term] id: CCO:I0007859 name: raf1-hras-1 physical interaction comment: Y2H: bait = C-Raf ,prey = HA-Ras-C-Ha-ras p21 protein xref: IntAct:EBI-537265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0007860 name: raf1-pbk physical interaction comment: Y2H: bait = C-Raf ,prey = TOPK/BPK-MPAKK-like protein kinase cap site form 2 xref: IntAct:EBI-537293 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002045 ! TOPK_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0007861 name: cdn1b-kpna3-3 physical interaction comment: in vitro transport assay of Flag-p27 KIP1 by importin alpha 3, importin beta, RAN and NTF2 xref: IntAct:EBI-591758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005931 ! IMA3_HUMAN relationship: has_participant CCO:B0006067 ! NTF2_HUMAN [Term] id: CCO:I0007862 name: cdn1b-kpna5-5 physical interaction comment: in vitro transport assay of Flag-p27 KIP1 by importin alpha 5, importin beta, RAN and NTF2 xref: IntAct:EBI-591792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005697 ! IMA5_HUMAN relationship: has_participant CCO:B0005931 ! IMA3_HUMAN relationship: has_participant CCO:B0006067 ! NTF2_HUMAN [Term] id: CCO:I0007863 name: trx-jab1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between thioredoxin and the COP9 signalosome complex subunit 5 protein xref: IntAct:EBI-594678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002025 ! CSN5_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN [Term] id: CCO:I0007864 name: mltk-mltk-1 acetylation comment: Homodimerization of MLTK deomonstrated y coimmunoprecipitation xref: IntAct:EBI-602285 is_a: CCO:Y0000002 ! acetylation reaction relationship: has_participant CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:I0007865 name: pkn1-mapk12-1 physical interaction comment: Interaction between PKN1 and p38gamma detected by coimmunoprecipitation xref: IntAct:EBI-602432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001665 ! MK12_HUMAN relationship: has_participant CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:I0007866 name: pkn1-mapk12-2 physical interaction comment: Interaction between PKN1 and p38gamma detected by coimmunoprecipitation xref: IntAct:EBI-602438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001665 ! MK12_HUMAN relationship: has_participant CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:I0007867 name: pkn1-map2k6-2 physical interaction comment: Interaction between PKN1 and MKK6 detected by coimmunoprecipitation xref: IntAct:EBI-602525 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0006068 ! PKN1_HUMAN [Term] id: CCO:I0007868 name: daxx-ar-3 physical interaction comment: Interaction of DAXX and AR detected by GST pull down. xref: IntAct:EBI-608157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN [Term] id: CCO:I0007869 name: hdac1-rbbp4-1 physical interaction comment: Co-ip of interaction between hdac1 and rbbp4 (RbAp48). xref: IntAct:EBI-620836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0007871 name: tacc1-chtog-7 physical interaction comment: Regions of interaction between TACC1 and chTOG identified by coimunoprecipitation xref: IntAct:EBI-624716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001772 ! CKAP5_HUMAN [Term] id: CCO:I0007872 name: hcfc1-pou2f1-1 physical interaction comment: Co-ip (in-vitro) of interaction between hcfc1 and pou2f1 (oct-1). xref: IntAct:EBI-624757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0006069 ! PO2F1_HUMAN [Term] id: CCO:I0007873 name: hcfc1-egr2-1 physical interaction comment: In-vivo one-hybrid recruitment assay demonstrating interaction between the beta-propeller of hcfc1 and the activation domain of egr2. xref: IntAct:EBI-625760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0006070 ! EGR2_HUMAN [Term] id: CCO:I0007874 name: cdkn2a-huew1-1 physical interaction comment: coip: bait = p14arf, preys = arf-bp1/mule, nucleophosmin xref: IntAct:EBI-625921 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0005709 ! HUWE1_HUMAN [Term] id: CCO:I0007875 name: hcfc1-zf-2 physical interaction comment: GST pull-down of interaction between hcfc1 and zf xref: IntAct:EBI-633035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0005710 ! ZHANG_HUMAN [Term] id: CCO:I0007876 name: brg1-baf200-1 physical interaction comment: coIP: bait = brg1, preys = baf200, baf170, baf155, baf60a, baf53, snf5, actin xref: IntAct:EBI-638007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN [Term] id: CCO:I0007877 name: egfr-pik3c2a-1 physical interaction comment: Interaction of PIK3C2A , PIK3C2B and EGFR demonstrated by coimmunorecipitation xref: IntAct:EBI-641139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN relationship: has_participant CCO:B0006071 ! P3C2A_HUMAN [Term] id: CCO:I0007878 name: egfr-pik3c2b-1 physical interaction comment: Interaction of PIK3C2B and EGFR demonstrated by coimmunoprecipitation xref: IntAct:EBI-641178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN [Term] id: CCO:I0007879 name: bcl2-bcl2-1 physical interaction comment: Homodimerization of Bcl-2demonstrated by coimmunoprecipitation xref: IntAct:EBI-700826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001506 ! BCL2_HUMAN [Term] id: CCO:I0007880 name: bcl2_bcl2_human direct interaction comment: BCL-2 homodimer xref: IntAct:EBI-706546 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN [Term] id: CCO:I0007881 name: bad_bcl2_human direct interaction comment: BAD:BCL-2 heterodimer xref: IntAct:EBI-706583 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN [Term] id: CCO:I0007882 name: bid_bcl2_human direct interaction comment: BID:BCL-2 heterodimer xref: IntAct:EBI-706842 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN [Term] id: CCO:I0007883 name: puma_bcl2_human direct interaction comment: PUMA:BCL-2 heterodimer xref: IntAct:EBI-707206 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN [Term] id: CCO:I0007884 name: bim_bcl2_human direct interaction comment: BIM:BCL-2 heterodimer xref: IntAct:EBI-709556 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0006003 ! BIM_HUMAN [Term] id: CCO:I0007885 name: supt5h-ppia-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006072 ! PPIA_HUMAN [Term] id: CCO:I0007886 name: axin1-anp32a-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-710496 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0006073 ! AN32A_HUMAN [Term] id: CCO:I0007887 name: axin1-crmp1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-710554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0007888 name: plk4-sfn-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001348 ! PLK4_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN [Term] id: CCO:I0007889 name: sufu-rcn3 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005248 ! RCN3_HUMAN [Term] id: CCO:I0007890 name: pex26-sufu-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0005312 ! PEX26_HUMAN [Term] id: CCO:I0007891 name: tak1l-gps2 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0005300 ! TAK1L_HUMAN [Term] id: CCO:I0007892 name: tada3l-usp5-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-761127 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005310 ! UBP5_HUMAN [Term] id: CCO:I0007893 name: pot1-terf2-1 physical interaction comment: Gel filtration reveals a complex consisting of POT1 , RAP1, TRF1, ACD, TERF2 and TINF2 proteins. xref: IntAct:EBI-765004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005503 ! POTE1_HUMAN relationship: has_participant CCO:B0005504 ! ACD_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:I0007894 name: tinf2-terf1-1 physical interaction comment: Colocalisation assay reveals interaction between TINF2, TRF1 and TRF2 proteins. xref: IntAct:EBI-765157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001810 ! TERF2_HUMAN [Term] id: CCO:I0007895 name: cyclina1_cdk1_human direct interaction comment: Cyclin A1: CDK1 xref: IntAct:EBI-766719 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN [Term] id: CCO:I0007896 name: cyclina2_cdk1_human direct interaction comment: Cyclin A2: CDK1 xref: IntAct:EBI-766779 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN [Term] id: CCO:I0007897 name: cyclina1_cdk2_human direct interaction comment: Cyclin A1: CDK2 xref: IntAct:EBI-767663 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN [Term] id: CCO:I0007898 name: cyclina2_cdk2_human direct interaction comment: Cyclin A2: CDK2 xref: IntAct:EBI-767671 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007899 name: cyclinb1_cdk1_human direct interaction comment: Cyclin B1: CDK1 xref: IntAct:EBI-767678 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN [Term] id: CCO:I0007900 name: cyclinb2_cdk1_human direct interaction comment: Cyclin B2: CDK1 xref: IntAct:EBI-767743 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001446 ! CCNB2_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN [Term] id: CCO:I0007901 name: cyclinb3_cdk2_human direct interaction comment: Cyclin B3: CDK2 xref: IntAct:EBI-767837 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0002007 ! CCNB3_HUMAN [Term] id: CCO:I0007902 name: cyclind1_cdk4_human direct interaction comment: Cyclin D1: CDK4 xref: IntAct:EBI-767849 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:I0007903 name: cyclind2_cdk4_human direct interaction comment: Cyclin D2: CDK4 xref: IntAct:EBI-767885 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001573 ! CCND2_HUMAN [Term] id: CCO:I0007904 name: cyclind3_cdk4_human direct interaction comment: Cyclin D3: CDK4 xref: IntAct:EBI-767922 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN [Term] id: CCO:I0007905 name: cyclind3_cdk6_human direct interaction comment: Cyclin D3: CDK6 xref: IntAct:EBI-768433 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0007906 name: cyclind1_cdk6_human direct interaction comment: Cyclin D1: CDK6 xref: IntAct:EBI-768466 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN [Term] id: CCO:I0007907 name: cycline1_cdk2_human direct interaction comment: Cyclin E1: CDK2 xref: IntAct:EBI-768477 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007908 name: cycline2_cdk2_human direct interaction comment: Cyclin E2: CDK2 xref: IntAct:EBI-768489 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007909 name: pol-prim_human physical interaction comment: DNA polymerase alpha:primase complex xref: IntAct:EBI-850302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0005507 ! PRI1_HUMAN relationship: has_participant CCO:B0005508 ! PRI2_HUMAN relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:I0007910 name: pold1-pold2-6 physical interaction comment: Assembly of DNA polymerase delta identifed by glycerol gradient centrifugation xref: IntAct:EBI-865073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:I0007911 name: pold1-pold2-7 physical interaction comment: Assembly of DNA polymerase delta identifed by glycerol gradient centrifugation xref: IntAct:EBI-865095 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:I0007912 name: dpol-delta_human physical interaction comment: DNA polymerase delta heterotetramer xref: IntAct:EBI-866690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN [Term] id: CCO:I0007913 name: dpol-epsilon_human physical interaction comment: DNA polymerase epsilon heterotetramer xref: IntAct:EBI-876717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN relationship: has_participant CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:I0007914 name: mcm2-7_human physical interaction comment: MCM2-7 heterohexomer xref: IntAct:EBI-913604 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:I0007915 name: wee1-plk1 phosphorylation xref: IntAct:EBI-914853 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN [Term] id: CCO:I0007916 name: pa2g4-hdac2-1 physical interaction xref: IntAct:EBI-924912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0007917 name: parafibromin-ctnnb1 physical interaction xref: IntAct:EBI-930154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:I0007918 name: ap2a-ubc9-1 physical interaction comment: Interaction between human AP2 alpha and UBC9 detected by Y2H xref: IntAct:EBI-937334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0007919 name: ap2b-ubc9-1 physical interaction comment: Interaction between human AP2 beta and UBC9 detected by Y2H xref: IntAct:EBI-937338 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005680 ! AP2B_HUMAN [Term] id: CCO:I0007920 name: ap2g-ubc9-2 physical interaction comment: Interaction between human AP2 gamma and UBC9 detected by Y2H xref: IntAct:EBI-937341 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005377 ! AP2C_HUMAN [Term] id: CCO:I0007921 name: ubc9-ap2a-1 physical interaction comment: Interaction between human UBC9 and APC alpha detected by Y2H xref: IntAct:EBI-937366 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN [Term] id: CCO:I0007922 name: ubc9-ap2b-1 physical interaction comment: Interaction between human UBC9 and APC beta detected by Y2H xref: IntAct:EBI-937371 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005680 ! AP2B_HUMAN [Term] id: CCO:I0007923 name: ubc9-ap2g-1 physical interaction comment: Interaction between human UBC9 and APC gamma detected by Y2H xref: IntAct:EBI-937381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0005377 ! AP2C_HUMAN [Term] id: CCO:I0007924 name: phb-tp53 colocalization comment: Colocalisation of Prohibitin and p53 protein xref: IntAct:EBI-985118 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN [Term] id: CCO:I0007925 name: brca2-rad51-5 physical interaction comment: Interaction between BRCA2 and RAD51 determined by GST-pulldown xref: IntAct:EBI-987097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007926 name: brca2-rad51-6 direct interaction comment: Interaction between BRCA2 and RAD51 determined by GST-pulldown xref: IntAct:EBI-987144 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007927 name: brca2-rad51-7 physical interaction comment: Interaction between BRCA2 and RAD51 determined by GST-pulldown xref: IntAct:EBI-987246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007928 name: daxx-usp7 physical interaction xref: IntAct:EBI-992452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007929 name: cdc27-nek2 physical interaction xref: IntAct:EBI-994872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001572 ! CDC27_HUMAN relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN [Term] id: CCO:I0007930 name: usp7-mdm2-3 direct interaction xref: IntAct:EBI-996897 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007931 name: usp7-tp53-4 physical interaction xref: IntAct:EBI-997438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007932 name: kntc2-spbc24-2 physical interaction xref: IntAct:EBI-1000048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN [Term] id: CCO:I0007933 name: bcl2-bid direct interaction xref: IntAct:EBI-1002129 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN [Term] id: CCO:I0007935 name: bcl2-bik direct interaction xref: IntAct:EBI-1002186 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005421 ! BIK_HUMAN [Term] id: CCO:I0007936 name: bcl2-bbc3 direct interaction xref: IntAct:EBI-1002234 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN [Term] id: CCO:I0007937 name: hras-sos1-2 direct interaction comment: Structural evidence for feedback activation by rasgtp of the ras-specific nucleotide exchange factor sos xref: IntAct:EBI-1035828 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:I0007938 name: hras-sos1-3 direct interaction comment: Structural evidence for feedback activation by rasgtp of the ras-specific nucleotide exchange factor sos xref: IntAct:EBI-1035839 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:I0007939 name: hras-sos1-4 direct interaction comment: Structural evidence for feedback activation by rasgtp of the ras-specific nucleotide exchange factor sos xref: IntAct:EBI-1035850 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:I0007940 name: hras-sos1-5 direct interaction comment: Structural evidence for feedback activation by rasgtp of the ras-specific nucleotide exchange factor sos xref: IntAct:EBI-1035861 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN [Term] id: CCO:I0007941 name: ccna2-cdk2-9 direct interaction comment: Structure of cdk2-cyclin a with pnu-292137 xref: IntAct:EBI-1039274 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN [Term] id: CCO:I0007942 name: apc-ctnnb1-1 physical interaction comment: Crystal structure of beta-catenin-icat helical domain-unphosphorylated apc r3 xref: IntAct:EBI-1039979 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN [Term] id: CCO:I0007943 name: fbxo11-skp1-1 physical interaction comment: Interaction between FBXO11, SKP1, CUL1 and RBX1(ROC1) identified by coimmunoprecipitation xref: IntAct:EBI-1168068 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0005332 ! FBX11_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0007944 name: rad51-rad51-6 physical interaction xref: IntAct:EBI-1178794 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007945 name: atm-aatf physical interaction comment: Che-1 coimmunoprecipitates with ATM xref: IntAct:EBI-1180741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0007946 name: cdc2l1-pak1-2 physical interaction comment: CDC2L1-PAK1 detection by immunoprecipitation xref: IntAct:EBI-1333 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:I0007947 name: brca2-rad51-3 physical interaction comment: Regions of BRCA2 neccessary for interaction determined by Y2H. xref: IntAct:EBI-298257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:I0007948 name: egfr-shc1-1 physical interaction comment: Interaction of the complex detected by CoIP. xref: IntAct:EBI-350217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001357 ! ANM5_HUMAN relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0001418 ! DNJA2_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001501 ! K2C7_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001689 ! PP1B_HUMAN relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0001754 ! TBB3_HUMAN relationship: has_participant CCO:B0002060 ! NEB2_HUMAN relationship: has_participant CCO:B0002186 ! RCC2_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005221 ! H31_HUMAN relationship: has_participant CCO:B0005224 ! PDLI7_HUMAN relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005449 ! TBA4A_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005563 ! RS20_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN relationship: has_participant CCO:B0005687 ! GRWD1_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0005700 ! H4_HUMAN relationship: has_participant CCO:B0005725 ! ROA2_HUMAN relationship: has_participant CCO:B0005729 ! DDX5_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005731 ! ANXA6_HUMAN relationship: has_participant CCO:B0005732 ! HNRH1_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0005734 ! RS8_HUMAN relationship: has_participant CCO:B0005736 ! ANXA2_HUMAN relationship: has_participant CCO:B0005741 ! RL18_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN relationship: has_participant CCO:B0005746 ! RL7_HUMAN relationship: has_participant CCO:B0005748 ! RS13_HUMAN relationship: has_participant CCO:B0005750 ! RS9_HUMAN relationship: has_participant CCO:B0005763 ! RS18_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0005774 ! ROA1_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005809 ! RBBP7_HUMAN relationship: has_participant CCO:B0005814 ! HNRPF_HUMAN relationship: has_participant CCO:B0005819 ! CBLB_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0005844 ! K1C17_HUMAN relationship: has_participant CCO:B0005847 ! MPCP_HUMAN relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0005855 ! RL12_HUMAN relationship: has_participant CCO:B0005856 ! RL24_HUMAN relationship: has_participant CCO:B0005859 ! RL27_HUMAN relationship: has_participant CCO:B0005861 ! RL4_HUMAN relationship: has_participant CCO:B0005862 ! RL21_HUMAN relationship: has_participant CCO:B0005864 ! RLA2_HUMAN relationship: has_participant CCO:B0005875 ! CD59_HUMAN relationship: has_participant CCO:B0005899 ! UAP56_HUMAN relationship: has_participant CCO:B0005900 ! K2C8_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0005968 ! MATR3_HUMAN relationship: has_participant CCO:B0006013 ! DDX6_HUMAN relationship: has_participant CCO:B0006060 ! DAPK3_HUMAN relationship: has_participant CCO:B0006072 ! PPIA_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0006125 ! CAPZB_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN relationship: has_participant CCO:B0006185 ! ODO2_HUMAN relationship: has_participant CCO:B0006226 ! DYL1_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN relationship: has_participant CCO:B0006300 ! RL18A_HUMAN relationship: has_participant CCO:B0006302 ! DREB_HUMAN relationship: has_participant CCO:B0015391 ! RL31_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN relationship: has_participant CCO:B0015638 ! ACTC_HUMAN relationship: has_participant CCO:B0015644 ! ACTH_HUMAN relationship: has_participant CCO:B0016306 ! PP2BA_HUMAN relationship: has_participant CCO:B0016505 ! KCC2D_HUMAN relationship: has_participant CCO:B0018244 ! SMD2_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN relationship: has_participant CCO:B0019513 ! TAOK2_HUMAN relationship: has_participant CCO:B0019878 ! TBB2C_HUMAN relationship: has_participant CCO:B0021502 ! ARP3_HUMAN relationship: has_participant CCO:B0021914 ! H2A2A_HUMAN relationship: has_participant CCO:B0024099 ! ARPC2_HUMAN relationship: has_participant CCO:B0024588 ! TBA1B_HUMAN relationship: has_participant CCO:B0025107 ! COR1B_HUMAN relationship: has_participant CCO:B0025115 ! COR1C_HUMAN relationship: has_participant CCO:B0028186 ! ARP2_HUMAN relationship: has_participant CCO:B0029592 ! RL36_HUMAN relationship: has_participant CCO:B0030465 ! RS23_HUMAN relationship: has_participant CCO:B0030784 ! FUSIP_HUMAN relationship: has_participant CCO:B0030969 ! RS3_HUMAN relationship: has_participant CCO:B0031823 ! MYO3B_HUMAN relationship: has_participant CCO:B0033309 ! COF2_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN relationship: has_participant CCO:B0034271 ! RS25_HUMAN relationship: has_participant CCO:B0038221 ! GSTM3_HUMAN relationship: has_participant CCO:B0038241 ! GSTM1_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN relationship: has_participant CCO:B0050497 ! PLEC1_HUMAN relationship: has_participant CCO:B0050501 ! EPIPL_HUMAN relationship: has_participant CCO:B0050621 ! WDR1_HUMAN relationship: has_participant CCO:B0051562 ! SRP09_HUMAN relationship: has_participant CCO:B0051611 ! GELS_HUMAN relationship: has_participant CCO:B0051620 ! ADSV_HUMAN relationship: has_participant CCO:B0054441 ! ARPC5_HUMAN relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0054618 ! PDCD6_HUMAN relationship: has_participant CCO:B0054761 ! TIAF1_HUMAN relationship: has_participant CCO:B0054998 ! IMDH2_HUMAN relationship: has_participant CCO:B0055266 ! DUT_HUMAN relationship: has_participant CCO:B0055316 ! SRP14_HUMAN relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN relationship: has_participant CCO:B0055736 ! SSB_HUMAN relationship: has_participant CCO:B0055765 ! PTN11_HUMAN relationship: has_participant CCO:B0055775 ! PRDX1_HUMAN relationship: has_participant CCO:B0055869 ! FLII_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN relationship: has_participant CCO:B0055964 ! SAFB2_HUMAN relationship: has_participant CCO:B0055995 ! ITPR3_HUMAN relationship: has_participant CCO:B0056170 ! FSCN1_HUMAN relationship: has_participant CCO:B0058087 ! HTRA1_HUMAN relationship: has_participant CCO:B0059132 ! LIMA1_HUMAN relationship: has_participant CCO:B0059207 ! VAV3_HUMAN relationship: has_participant CCO:B0059320 ! TR150_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN relationship: has_participant CCO:B0062824 ! AP2M1_HUMAN relationship: has_participant CCO:B0062985 ! PIMT_HUMAN relationship: has_participant CCO:B0062989 ! LMNA_HUMAN relationship: has_participant CCO:B0063029 ! KPYM_HUMAN relationship: has_participant CCO:B0063038 ! UACA_HUMAN relationship: has_participant CCO:B0063048 ! RL35A_HUMAN relationship: has_participant CCO:B0063061 ! RS5_HUMAN relationship: has_participant CCO:B0063063 ! MYO1C_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN relationship: has_participant CCO:B0063078 ! RS16_HUMAN relationship: has_participant CCO:B0063083 ! RL3_HUMAN relationship: has_participant CCO:B0063085 ! RS11_HUMAN relationship: has_participant CCO:B0063093 ! RL10_HUMAN relationship: has_participant CCO:B0063097 ! TMOD3_HUMAN relationship: has_participant CCO:B0063100 ! SERA_HUMAN relationship: has_participant CCO:B0063101 ! MYO1B_HUMAN relationship: has_participant CCO:B0063113 ! MYPT1_HUMAN relationship: has_participant CCO:B0063121 ! MYO1A_HUMAN relationship: has_participant CCO:B0063182 ! EF2_HUMAN relationship: has_participant CCO:B0063202 ! ATD3A_HUMAN relationship: has_participant CCO:B0063230 ! Q9Y6X7_HUMAN relationship: has_participant CCO:B0063347 ! LMO7_HUMAN relationship: has_participant CCO:B0063352 ! H2B1H_HUMAN relationship: has_participant CCO:B0063353 ! RS26_HUMAN relationship: has_participant CCO:B0063354 ! AP2A1_HUMAN relationship: has_participant CCO:B0063355 ! HNRH2_HUMAN relationship: has_participant CCO:B0063356 ! RL27A_HUMAN relationship: has_participant CCO:B0063357 ! UGDH_HUMAN relationship: has_participant CCO:B0063358 ! ADT1_HUMAN relationship: has_participant CCO:B0063359 ! DLDH_HUMAN relationship: has_participant CCO:B0063360 ! RL23A_HUMAN relationship: has_participant CCO:B0063361 ! GLYM_HUMAN relationship: has_participant CCO:B0063362 ! TPM2_HUMAN relationship: has_participant CCO:B0063363 ! SERPH_HUMAN relationship: has_participant CCO:B0063364 ! ARPC4_HUMAN relationship: has_participant CCO:B0063365 ! ABLM3_HUMAN relationship: has_participant CCO:B0063366 ! GMFB_HUMAN relationship: has_participant CCO:B0063367 ! RL26_HUMAN relationship: has_participant CCO:B0063368 ! RS28_HUMAN relationship: has_participant CCO:B0063369 ! TPM1_HUMAN relationship: has_participant CCO:B0063370 ! SRC8_HUMAN relationship: has_participant CCO:B0063371 ! CBR1_HUMAN relationship: has_participant CCO:B0063372 ! CT160_HUMAN [Term] id: CCO:I0007949 name: tp53-hmgb1 physical interaction comment: p53 binds directly to HMG-1 in vitro xref: IntAct:EBI-389443 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN [Term] id: CCO:I0007950 name: lats1-zyx-2 physical interaction comment: Interaction betwen human LATS1 and ZYX confirmed by co-immunoprecipitation xref: IntAct:EBI-444251 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007951 name: lats1-zyx-3 physical interaction comment: Interaction betwen human LATS1 and ZYX confirmed by co-immunoprecipitation xref: IntAct:EBI-444278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007952 name: lats1-zyx-5 physical interaction comment: Interaction betwen human LATS1 and ZYX, domains defined by GST pull down xref: IntAct:EBI-444288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007953 name: lats1-zyx-7 physical interaction comment: Interaction betwen human LATS1 and ZYX, phosporylation requirement defined by GST pull down xref: IntAct:EBI-444303 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007954 name: hif1a-ep300-1 physical interaction comment: Interaction of HIF1A with EP300 confirmed by GST-pull down. xref: IntAct:EBI-447320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN [Term] id: CCO:I0007956 name: epas1-ep300-1 physical interaction comment: Interaction of EPAS1 with EP300 confirmed by GST-pull down. xref: IntAct:EBI-447503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0006077 ! EPAS1_HUMAN [Term] id: CCO:I0007957 name: cdt1-gmnn-4 physical interaction comment: Interaction between Geminin and CDT1 identified by GST-pull-down xref: IntAct:EBI-456975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:I0007958 name: lats1-zyx-8 physical interaction comment: Interaction betwen human LATS1 and ZYX, domains defined by GST pull down xref: IntAct:EBI-464050 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007959 name: lats1-zyx-9 physical interaction comment: Interaction betwen human LATS1 and ZYX, domains defined by GST pull down xref: IntAct:EBI-491492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007960 name: lats1-zyx-10 physical interaction comment: Interaction betwen human LATS1 and ZYX, domains defined by GST pull down xref: IntAct:EBI-491502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0007961 name: pb1-arid2-1 physical interaction comment: coIP: bait = baf180; prey = baf200 xref: IntAct:EBI-637806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0007962 name: gnl3-ppp2r5a physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the nucleostemin protein and PPP2R5A protein xref: IntAct:EBI-641677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002103 ! GNL3_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0007963 name: egfr-yes-2 physical interaction comment: Proteomics studies using anti-EGFR affinity chromatography xref: IntAct:EBI-702413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001437 ! BCAR3_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0005465 ! YES_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005812 ! FAK1_HUMAN relationship: has_participant CCO:B0005824 ! CTNA1_HUMAN relationship: has_participant CCO:B0005826 ! PKP2_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0005832 ! EPHA2_HUMAN relationship: has_participant CCO:B0005836 ! ACK1_HUMAN relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0005839 ! CTND1_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005846 ! FAK2_HUMAN [Term] id: CCO:I0007964 name: hck-sam68-1 physical interaction comment: In vitro pull-down: bait= hck SH3 domain, prey = sam68 xref: IntAct:EBI-780858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0007965 name: lck-sam68-1 physical interaction comment: In vitro pull-down: bait= Lck SH3 domain, prey = sam68 xref: IntAct:EBI-780873 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN [Term] id: CCO:I0007966 name: grb2-sam68-1 physical interaction comment: In vitro pull-down: bait= Grb2 SH3 domain 1, prey = sam68 xref: IntAct:EBI-780898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0007967 name: grb2-sam68-2 physical interaction comment: In vitro pull-down: bait= Grb2 SH3 domain 2, prey = sam68 xref: IntAct:EBI-780909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0007968 name: pold1pold2-8 physical interaction comment: Interaction of POLD4 with POLD1 identified by coimmunoprecipitation xref: IntAct:EBI-865108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN [Term] id: CCO:I0007969 name: myc-nmi-1 physical interaction comment: Interaction between human Myc and Nmi detected by beta galactosidase assay xref: IntAct:EBI-878432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0007970 name: disc1-tubg-1 physical interaction comment: Co-sedimentation of DISC1 protein, gamma tubulin protein and Pericentrin protein xref: IntAct:EBI-930616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001548 ! TBG1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0006078 ! PCNT_HUMAN [Term] id: CCO:I0007971 name: ubp7-daxx-10 physical interaction xref: IntAct:EBI-993044 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0007972 name: mbde-suv93h1-2 physical interaction xref: IntAct:EBI-994609 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0007973 name: suv93h1-mbde-2 physical interaction xref: IntAct:EBI-994624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0007974 name: suv93h1-cbx-1 physical interaction xref: IntAct:EBI-994679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005317 ! CBX5_HUMAN [Term] id: CCO:I0007975 name: suv93h1-hdac1-1 physical interaction xref: IntAct:EBI-994733 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0007976 name: suv93h1-hdac1-2 physical interaction xref: IntAct:EBI-994740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0007977 name: suv93h1-hdac2-1 physical interaction xref: IntAct:EBI-994747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0007978 name: suv93h1-hdac2-2 physical interaction xref: IntAct:EBI-994754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0007979 name: ubqln4-ptn physical interaction xref: IntAct:EBI-728453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0007981 name: cdk4-cdkn2b physical interaction xref: IntAct:EBI-728471 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN [Term] id: CCO:I0007982 name: cdkn2c-tp53 physical interaction xref: IntAct:EBI-728477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN [Term] id: CCO:I0007983 name: cdkn2c-unc119 physical interaction xref: IntAct:EBI-728480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0007984 name: cpe-rif1 physical interaction xref: IntAct:EBI-728492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006081 ! CBPE_HUMAN [Term] id: CCO:I0007985 name: dleu1-eef1a1 physical interaction xref: IntAct:EBI-728504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0007986 name: dleu1-eef1g physical interaction xref: IntAct:EBI-728507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0007987 name: erh-tp53 physical interaction xref: IntAct:EBI-728513 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001703 ! ERH_HUMAN [Term] id: CCO:I0007988 name: psmd2-ptn physical interaction xref: IntAct:EBI-728570 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN [Term] id: CCO:I0007989 name: ptn-chd3 physical interaction xref: IntAct:EBI-728573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0007990 name: rpa2-rif1 physical interaction xref: IntAct:EBI-728609 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN [Term] id: CCO:I0007991 name: selenbp1-rif1 physical interaction xref: IntAct:EBI-728645 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006083 ! SBP1_HUMAN [Term] id: CCO:I0007992 name: sgta-ptn physical interaction xref: IntAct:EBI-728657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006084 ! SGTA_HUMAN [Term] id: CCO:I0007993 name: znf24-tp53 physical interaction xref: IntAct:EBI-728684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0007994 name: arih2-ptn physical interaction xref: IntAct:EBI-728729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005288 ! ARI2_HUMAN [Term] id: CCO:I0007995 name: arih2-tp53 physical interaction xref: IntAct:EBI-728735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005288 ! ARI2_HUMAN [Term] id: CCO:I0007996 name: ascc2-rpa1 physical interaction xref: IntAct:EBI-728745 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:I0007997 name: axin1-crmp1-1 physical interaction xref: IntAct:EBI-728754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0007998 name: axin1-eef1a1 physical interaction xref: IntAct:EBI-728757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0007999 name: btbd2-tp53 physical interaction xref: IntAct:EBI-728781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005933 ! BTBD2_HUMAN [Term] id: CCO:I0008000 name: ccl18-tp53 physical interaction xref: IntAct:EBI-728811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006087 ! CCL18_HUMAN [Term] id: CCO:I0008002 name: cdc42-rif1 physical interaction xref: IntAct:EBI-728820 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0008003 name: cdc42-tp53 physical interaction xref: IntAct:EBI-728823 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0008004 name: cdk4-capns1 physical interaction xref: IntAct:EBI-728826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN [Term] id: CCO:I0008005 name: cdkn2c-rif1 physical interaction xref: IntAct:EBI-728835 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008006 name: cks2-eef1a1 physical interaction xref: IntAct:EBI-728838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0008007 name: cks2-unc119 physical interaction xref: IntAct:EBI-728841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0008008 name: cox17-rif1 physical interaction xref: IntAct:EBI-728844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006089 ! COX17_HUMAN [Term] id: CCO:I0008009 name: cpe-rpa1 physical interaction xref: IntAct:EBI-728847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0006081 ! CBPE_HUMAN [Term] id: CCO:I0008010 name: eif2s2-tp53 physical interaction xref: IntAct:EBI-728919 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006090 ! IF2B_HUMAN [Term] id: CCO:I0008011 name: erh-tle1 physical interaction xref: IntAct:EBI-728928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001703 ! ERH_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0008012 name: fts-rpa1 physical interaction xref: IntAct:EBI-728931 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0026276 ! AKTIP_HUMAN [Term] id: CCO:I0008013 name: gnb2l1-ptn physical interaction xref: IntAct:EBI-728946 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005739 ! GBLP_HUMAN [Term] id: CCO:I0008014 name: hrmt1l2-rif1 physical interaction xref: IntAct:EBI-728973 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005713 ! ANM1_HUMAN [Term] id: CCO:I0008015 name: hspe1-rif1 physical interaction xref: IntAct:EBI-728979 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006092 ! CH10_HUMAN [Term] id: CCO:I0008016 name: kif15-kiaa1377 physical interaction xref: IntAct:EBI-729003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002165 ! KIF15_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008017 name: lama4-rif1 physical interaction xref: IntAct:EBI-729015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN [Term] id: CCO:I0008018 name: lama4-tp53 physical interaction xref: IntAct:EBI-729018 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN [Term] id: CCO:I0008019 name: loc51236-ptn physical interaction xref: IntAct:EBI-729033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006094 ! Q96BK8_HUMAN [Term] id: CCO:I0008020 name: loc51236-rpa1 physical interaction xref: IntAct:EBI-729036 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0006094 ! Q96BK8_HUMAN [Term] id: CCO:I0008021 name: mad2l1bp-tp53 physical interaction xref: IntAct:EBI-729048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN [Term] id: CCO:I0008022 name: mphosph6-tle1 physical interaction xref: IntAct:EBI-729063 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0008023 name: mphosph6-tp53 physical interaction xref: IntAct:EBI-729066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0002071 ! MPH6_HUMAN [Term] id: CCO:I0008024 name: mrps12-rif1 physical interaction xref: IntAct:EBI-729069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006095 ! RT12_HUMAN [Term] id: CCO:I0008025 name: naca-rif1 physical interaction xref: IntAct:EBI-729072 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:I0008026 name: nhp2l1-cdkn2c physical interaction xref: IntAct:EBI-729075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001676 ! NH2L1_HUMAN [Term] id: CCO:I0008027 name: np-rif1 physical interaction xref: IntAct:EBI-729081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006097 ! PNPH_HUMAN [Term] id: CCO:I0008028 name: pafah1b3-rif1 physical interaction xref: IntAct:EBI-729099 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN [Term] id: CCO:I0008029 name: pafah1b3-tp53 physical interaction xref: IntAct:EBI-729105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN [Term] id: CCO:I0008030 name: pcdha4-tp53 physical interaction xref: IntAct:EBI-729123 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006099 ! PCDA4_HUMAN [Term] id: CCO:I0008031 name: polr2c-rif1 physical interaction xref: IntAct:EBI-729132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006100 ! RPB3_HUMAN [Term] id: CCO:I0008032 name: polr3f-rif1 physical interaction xref: IntAct:EBI-729138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006101 ! RPC6_HUMAN [Term] id: CCO:I0008033 name: pp-tp53 physical interaction xref: IntAct:EBI-729141 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006102 ! IPYR_HUMAN [Term] id: CCO:I0008034 name: ppp2ca-ptn physical interaction xref: IntAct:EBI-729147 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN [Term] id: CCO:I0008035 name: psmd11-ptn physical interaction xref: IntAct:EBI-729162 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0008036 name: psmd11-rif1 physical interaction xref: IntAct:EBI-729165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0008037 name: psmd11-tp53 physical interaction xref: IntAct:EBI-729171 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0008038 name: psmd2-rif1 physical interaction xref: IntAct:EBI-729183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008039 name: psmd2-unc119 physical interaction xref: IntAct:EBI-729186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0008040 name: ptprs-ptn physical interaction xref: IntAct:EBI-729195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006104 ! PTPRS_HUMAN [Term] id: CCO:I0008041 name: rad51-chd3 physical interaction xref: IntAct:EBI-729210 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001721 ! RAD51_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0008042 name: rfc5-rif1 physical interaction xref: IntAct:EBI-729213 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN [Term] id: CCO:I0008043 name: rgs2-git1 physical interaction xref: IntAct:EBI-729219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:I0008044 name: rnpc4-rpa1 physical interaction xref: IntAct:EBI-729222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0006106 ! Q6IA98_HUMAN [Term] id: CCO:I0008045 name: rplp1-ptn physical interaction xref: IntAct:EBI-729231 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:I0008046 name: rplp1-rif1 physical interaction xref: IntAct:EBI-729234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:I0008047 name: sat-rif1 physical interaction xref: IntAct:EBI-729261 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0008048 name: sat-tp53 physical interaction xref: IntAct:EBI-729264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0008049 name: selenbp1-rpa1 physical interaction xref: IntAct:EBI-729270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0006083 ! SBP1_HUMAN [Term] id: CCO:I0008050 name: serpinb9-rif1 physical interaction xref: IntAct:EBI-729282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0008051 name: serpinb9-tp53 physical interaction xref: IntAct:EBI-729288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0008052 name: sma3-tp53 physical interaction xref: IntAct:EBI-729321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0041277 ! GUSP1_HUMAN [Term] id: CCO:I0008053 name: smn1-rif1 physical interaction xref: IntAct:EBI-729327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006110 ! SMN_HUMAN [Term] id: CCO:I0008054 name: snrpn-tp53 physical interaction xref: IntAct:EBI-729339 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006111 ! RSMN_HUMAN [Term] id: CCO:I0008055 name: sult1e1-tp53 physical interaction xref: IntAct:EBI-729348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006112 ! ST1E1_HUMAN [Term] id: CCO:I0008056 name: supt5h-med31 physical interaction xref: IntAct:EBI-729354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0008057 name: tada3l-sap18 physical interaction xref: IntAct:EBI-729357 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0006113 ! SAP18_HUMAN [Term] id: CCO:I0008058 name: tk1-rif1 physical interaction xref: IntAct:EBI-729378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006114 ! KITH_HUMAN [Term] id: CCO:I0008059 name: tk1-tp53 physical interaction xref: IntAct:EBI-729384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006114 ! KITH_HUMAN [Term] id: CCO:I0008060 name: tmsb4x-tp53 physical interaction xref: IntAct:EBI-729393 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006115 ! TYB4_HUMAN [Term] id: CCO:I0008061 name: tomm20-ptn physical interaction xref: IntAct:EBI-729405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006116 ! TOM20_HUMAN [Term] id: CCO:I0008062 name: znf24-rif1 physical interaction xref: IntAct:EBI-729450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0008063 name: akr1c3-rif1 physical interaction xref: IntAct:EBI-729471 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006117 ! AK1C3_HUMAN [Term] id: CCO:I0008064 name: ankrd24-rif1 physical interaction xref: IntAct:EBI-729480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0040685 ! ANR24_HUMAN [Term] id: CCO:I0008065 name: anxa3-tp53 physical interaction xref: IntAct:EBI-729483 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006119 ! ANXA3_HUMAN [Term] id: CCO:I0008066 name: arih2-centd2 physical interaction xref: IntAct:EBI-729531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0005288 ! ARI2_HUMAN [Term] id: CCO:I0008067 name: arl3-rif1 physical interaction xref: IntAct:EBI-729549 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006120 ! ARL3_HUMAN [Term] id: CCO:I0008068 name: arl3-tp53 physical interaction xref: IntAct:EBI-729555 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006120 ! ARL3_HUMAN [Term] id: CCO:I0008069 name: atf3-tp53 physical interaction xref: IntAct:EBI-729588 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN [Term] id: CCO:I0008070 name: atp5c1-ptn physical interaction xref: IntAct:EBI-729597 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:I0008071 name: axin1-anp32a physical interaction xref: IntAct:EBI-729609 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0006073 ! AN32A_HUMAN [Term] id: CCO:I0008072 name: bcr-tp53 physical interaction xref: IntAct:EBI-729618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006123 ! BCR_HUMAN [Term] id: CCO:I0008073 name: bmi1-rif1 physical interaction xref: IntAct:EBI-729636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006124 ! Q5T8Z1_HUMAN [Term] id: CCO:I0008074 name: capzb-ptn physical interaction xref: IntAct:EBI-729693 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006125 ! CAPZB_HUMAN [Term] id: CCO:I0008075 name: cbx1-rif1 physical interaction xref: IntAct:EBI-729699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006126 ! CBX1_HUMAN [Term] id: CCO:I0008076 name: cct5-tp53 physical interaction xref: IntAct:EBI-729723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005291 ! TCPE_HUMAN [Term] id: CCO:I0008077 name: cct7-med31 physical interaction xref: IntAct:EBI-729726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002089 ! TCPH_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0008078 name: cct7-htatip physical interaction xref: IntAct:EBI-729729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002089 ! TCPH_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:I0008079 name: cdk4-bat3 physical interaction xref: IntAct:EBI-729744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:I0008080 name: cdk4-setdb1 physical interaction xref: IntAct:EBI-729747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0008081 name: cdkn2b-kiaa1377 physical interaction xref: IntAct:EBI-729762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008082 name: cdkn2c-dkfzp564o0523 physical interaction xref: IntAct:EBI-729765 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0008083 name: cdkn2c-drap1 physical interaction xref: IntAct:EBI-729768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0008084 name: cdkn2c-tle1 physical interaction xref: IntAct:EBI-729771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0008085 name: cetn3-pde6d physical interaction xref: IntAct:EBI-729774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0006130 ! PDE6D_HUMAN [Term] id: CCO:I0008086 name: cetn3-rif1 physical interaction xref: IntAct:EBI-729777 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008087 name: cetn3-unc119 physical interaction xref: IntAct:EBI-729780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0008088 name: ckmt2-rif1 physical interaction xref: IntAct:EBI-729792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006131 ! KCRS_HUMAN [Term] id: CCO:I0008089 name: cox17-tp53 physical interaction xref: IntAct:EBI-729807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006089 ! COX17_HUMAN [Term] id: CCO:I0008090 name: creld1-ptn physical interaction xref: IntAct:EBI-729828 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006132 ! CREL1_HUMAN [Term] id: CCO:I0008091 name: dkc1-eef1g physical interaction xref: IntAct:EBI-729861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001415 ! DKC1_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0008092 name: dleu1-med31 physical interaction xref: IntAct:EBI-729870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0008093 name: dleu1-cops6 physical interaction xref: IntAct:EBI-729873 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0008094 name: dleu1-htatip physical interaction xref: IntAct:EBI-729876 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:I0008095 name: dleu1-kiaa1377 physical interaction xref: IntAct:EBI-729879 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008096 name: dleu1-utp14a physical interaction xref: IntAct:EBI-729882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0008097 name: dleu1-tp53 physical interaction xref: IntAct:EBI-729885 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN [Term] id: CCO:I0008098 name: dleu1-ubr1 physical interaction xref: IntAct:EBI-729891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:I0008099 name: dnajb11-ptn physical interaction xref: IntAct:EBI-729894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006136 ! DJB11_HUMAN [Term] id: CCO:I0008100 name: dnajb9-plk1 physical interaction xref: IntAct:EBI-729900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0006137 ! DNJB9_HUMAN [Term] id: CCO:I0008101 name: dnmt2-rif1 physical interaction xref: IntAct:EBI-729915 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN [Term] id: CCO:I0008102 name: eif3s5-ptn physical interaction xref: IntAct:EBI-729936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0026277 ! EIF3F_HUMAN [Term] id: CCO:I0008103 name: erh-med31 physical interaction xref: IntAct:EBI-729954 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001703 ! ERH_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0008105 name: erh-setdb1 physical interaction xref: IntAct:EBI-729960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001703 ! ERH_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0008107 name: fxr1-rif1 physical interaction xref: IntAct:EBI-730042 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006140 ! FXR1_HUMAN [Term] id: CCO:I0008108 name: fxyd6-tp53 physical interaction xref: IntAct:EBI-730048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006141 ! FXYD6_HUMAN [Term] id: CCO:I0008109 name: gnb5-mcm2 physical interaction xref: IntAct:EBI-730063 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0006142 ! GBB5_HUMAN [Term] id: CCO:I0008110 name: gpd1-ptn physical interaction xref: IntAct:EBI-730069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006143 ! GPDA_HUMAN [Term] id: CCO:I0008111 name: gps2-chd3 physical interaction xref: IntAct:EBI-730072 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0008112 name: gps2-setdb1 physical interaction xref: IntAct:EBI-730075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0008113 name: gstm4-rif1 physical interaction xref: IntAct:EBI-730078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006144 ! GSTM4_HUMAN [Term] id: CCO:I0008114 name: gstm4-tp53 physical interaction xref: IntAct:EBI-730084 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006144 ! GSTM4_HUMAN [Term] id: CCO:I0008115 name: gstp1-ptn physical interaction xref: IntAct:EBI-730096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN [Term] id: CCO:I0008116 name: hbxip-rif1 physical interaction xref: IntAct:EBI-730114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:I0008117 name: hla_dqa1-rif1 physical interaction xref: IntAct:EBI-730117 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006147 ! HA23_HUMAN [Term] id: CCO:I0008118 name: hmg20b-vim physical interaction xref: IntAct:EBI-730126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002184 ! HM20B_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0008119 name: hmgb1-rif1 physical interaction xref: IntAct:EBI-730129 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN [Term] id: CCO:I0008120 name: hmox2-rif1 physical interaction xref: IntAct:EBI-730144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006148 ! HMOX2_HUMAN [Term] id: CCO:I0008123 name: hspb1-rif1 physical interaction xref: IntAct:EBI-730186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:I0008124 name: hspb1-tp53 physical interaction xref: IntAct:EBI-730189 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:I0008125 name: id2-rif1 physical interaction xref: IntAct:EBI-730207 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006149 ! ID2_HUMAN [Term] id: CCO:I0008126 name: kif15-chd3 physical interaction xref: IntAct:EBI-730243 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002165 ! KIF15_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0008127 name: kif15-vim physical interaction xref: IntAct:EBI-730246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002165 ! KIF15_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0008128 name: lama4-ptn physical interaction xref: IntAct:EBI-730252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN [Term] id: CCO:I0008129 name: luc7l2-ptn physical interaction xref: IntAct:EBI-730279 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:I0008130 name: mad2l1bp-eef1a1 physical interaction xref: IntAct:EBI-730288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0008131 name: mad2l1bp-htatip physical interaction xref: IntAct:EBI-730291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:I0008132 name: mad2l1bp-ptn physical interaction xref: IntAct:EBI-730294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN [Term] id: CCO:I0008133 name: mad2l1bp-setdb1 physical interaction xref: IntAct:EBI-730297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0008134 name: mphosph6-rif1 physical interaction xref: IntAct:EBI-730339 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0002071 ! MPH6_HUMAN [Term] id: CCO:I0008135 name: mphosph6-unc119 physical interaction xref: IntAct:EBI-730342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0008136 name: mphosph6-zhx1 physical interaction xref: IntAct:EBI-730345 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:I0008137 name: nme3-nme2 physical interaction xref: IntAct:EBI-730402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0005316 ! NDK3_HUMAN [Term] id: CCO:I0008138 name: np-tp53 physical interaction xref: IntAct:EBI-730408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006097 ! PNPH_HUMAN [Term] id: CCO:I0008139 name: p4hb-ptn physical interaction xref: IntAct:EBI-730426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006151 ! PDIA1_HUMAN [Term] id: CCO:I0008140 name: pcdha4-rif1 physical interaction xref: IntAct:EBI-730483 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006099 ! PCDA4_HUMAN [Term] id: CCO:I0008141 name: pdcd5-rif1 physical interaction xref: IntAct:EBI-730495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006152 ! PDCD5_HUMAN [Term] id: CCO:I0008142 name: pfdn1-med31 physical interaction xref: IntAct:EBI-730501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0008143 name: pfdn1-git1 physical interaction xref: IntAct:EBI-730504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:I0008144 name: pfdn1-hap1 physical interaction xref: IntAct:EBI-730507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0006153 ! HAP1_HUMAN [Term] id: CCO:I0008145 name: pfdn1-kiaa1377 physical interaction xref: IntAct:EBI-730510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008146 name: pfdn1-rif1 physical interaction xref: IntAct:EBI-730513 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008147 name: pfdn1-rplp1 physical interaction xref: IntAct:EBI-730516 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:I0008148 name: pfn1-rif1 physical interaction xref: IntAct:EBI-730522 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006154 ! PROF1_HUMAN [Term] id: CCO:I0008149 name: pmf1-cops6 physical interaction xref: IntAct:EBI-730531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0008150 name: pmf1-git1 physical interaction xref: IntAct:EBI-730534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:I0008151 name: sept5-pfn2 physical interaction xref: IntAct:EBI-730537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0008152 name: prei3-mcm2 physical interaction xref: IntAct:EBI-730585 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0008153 name: prei3-rif1 physical interaction xref: IntAct:EBI-730594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0008154 name: psg9-rif1 physical interaction xref: IntAct:EBI-730612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006157 ! PSG9_HUMAN [Term] id: CCO:I0008155 name: rad51-vim physical interaction xref: IntAct:EBI-730657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001721 ! RAD51_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0008156 name: rbm5-rif1 physical interaction xref: IntAct:EBI-730660 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001660 ! RBM5_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008157 name: rgs2-ddr1 physical interaction xref: IntAct:EBI-730672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006158 ! DDR1_HUMAN [Term] id: CCO:I0008158 name: rgs2-hspa8 physical interaction xref: IntAct:EBI-730675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0008159 name: s100a8-rif1 physical interaction xref: IntAct:EBI-730729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006159 ! S10A8_HUMAN [Term] id: CCO:I0008160 name: crlz1-ptn physical interaction xref: IntAct:EBI-730738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006160 ! SAS10_HUMAN [Term] id: CCO:I0008161 name: sat-ptn physical interaction xref: IntAct:EBI-730762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0008162 name: sfpq-rps27a physical interaction xref: IntAct:EBI-730807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0008163 name: rps27a-sfpq physical interaction xref: IntAct:EBI-730810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001695 ! UBIQ_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0008164 name: snrpn-rif1 physical interaction xref: IntAct:EBI-730882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006111 ! RSMN_HUMAN [Term] id: CCO:I0008165 name: socs3-pin1 physical interaction xref: IntAct:EBI-730888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN [Term] id: CCO:I0008166 name: src-khdrbs1 physical interaction xref: IntAct:EBI-730897 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0005464 ! SRC_HUMAN [Term] id: CCO:I0008167 name: ssr1-ptn physical interaction xref: IntAct:EBI-730903 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006163 ! SSRA_HUMAN [Term] id: CCO:I0008168 name: stx5a-tp53 physical interaction xref: IntAct:EBI-730918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006164 ! STX5_HUMAN [Term] id: CCO:I0008169 name: sult1e1-rif1 physical interaction xref: IntAct:EBI-730924 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006112 ! ST1E1_HUMAN [Term] id: CCO:I0008170 name: supt5h-kiaa1377 physical interaction xref: IntAct:EBI-730930 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008171 name: supt5h-rpl8 physical interaction xref: IntAct:EBI-730933 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0005860 ! RL8_HUMAN [Term] id: CCO:I0008172 name: terf1-git1 physical interaction xref: IntAct:EBI-730945 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN [Term] id: CCO:I0008173 name: terf1-pfn2 physical interaction xref: IntAct:EBI-730948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0008174 name: terf1-zhx1 physical interaction xref: IntAct:EBI-730951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:I0008175 name: tmsb4x-rif1 physical interaction xref: IntAct:EBI-731005 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006115 ! TYB4_HUMAN [Term] id: CCO:I0008176 name: pbk-gps2 physical interaction xref: IntAct:EBI-731026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0002045 ! TOPK_HUMAN [Term] id: CCO:I0008178 name: tp53bp2-eef1a1 physical interaction xref: IntAct:EBI-731032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0008179 name: tp53bp2-kif5a physical interaction xref: IntAct:EBI-731035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0006166 ! KIF5A_HUMAN [Term] id: CCO:I0008180 name: tp53bp2-ptn physical interaction xref: IntAct:EBI-731038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN [Term] id: CCO:I0008181 name: tp53bp2-utp14a physical interaction xref: IntAct:EBI-731041 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0008182 name: tp53bp2-unc119 physical interaction xref: IntAct:EBI-731044 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0008183 name: tubb4-khdrbs1 physical interaction xref: IntAct:EBI-731071 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0006167 ! TBB4_HUMAN [Term] id: CCO:I0008184 name: ube2i-unc119 physical interaction xref: IntAct:EBI-731083 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0008185 name: ube2v2-igsf21 physical interaction xref: IntAct:EBI-731086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001813 ! UB2V2_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0008186 name: vim-rif1 physical interaction xref: IntAct:EBI-731104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0008187 name: wdr33-tp53 physical interaction xref: IntAct:EBI-731113 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:I0008188 name: klhlx-rif1 physical interaction xref: IntAct:EBI-731158 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006170 ! Q5ZF45_HUMAN [Term] id: CCO:I0008189 name: arhh-rif1 physical interaction xref: IntAct:EBI-731218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006171 ! Q6ICP4_HUMAN [Term] id: CCO:I0008190 name: arih2-ppp2r1a physical interaction xref: IntAct:EBI-731233 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0005288 ! ARI2_HUMAN [Term] id: CCO:I0008191 name: arpc3-cdkn2b physical interaction xref: IntAct:EBI-731245 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN [Term] id: CCO:I0008192 name: atf3-rif1 physical interaction xref: IntAct:EBI-731302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN [Term] id: CCO:I0008193 name: atp1b1-rif1 physical interaction xref: IntAct:EBI-731305 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005453 ! AT1B1_HUMAN [Term] id: CCO:I0008194 name: atp5c1-ccnd3 physical interaction xref: IntAct:EBI-731308 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:I0008196 name: atrx-ptn physical interaction xref: IntAct:EBI-731356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:I0008197 name: axin1-axin1 physical interaction xref: IntAct:EBI-731362 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN [Term] id: CCO:I0008198 name: axin1-gak physical interaction xref: IntAct:EBI-731365 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001364 ! GAK_HUMAN relationship: has_participant CCO:B0001367 ! AXN1_HUMAN [Term] id: CCO:I0008199 name: axin1-utp14a physical interaction xref: IntAct:EBI-731368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0008200 name: bcar1-ppp1r15a physical interaction xref: IntAct:EBI-731386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001436 ! PR15A_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:I0008201 name: bmi1-ptn physical interaction xref: IntAct:EBI-731404 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006124 ! Q5T8Z1_HUMAN [Term] id: CCO:I0008202 name: brms1-eef1a1 physical interaction xref: IntAct:EBI-731416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0008203 name: brms1-rif1 physical interaction xref: IntAct:EBI-731419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN [Term] id: CCO:I0008204 name: btbd2-ptn physical interaction xref: IntAct:EBI-731437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005933 ! BTBD2_HUMAN [Term] id: CCO:I0008205 name: c19orf14-rif1 physical interaction xref: IntAct:EBI-731458 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:I0008206 name: ubqln4-smarcb1 physical interaction xref: IntAct:EBI-731464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0008207 name: c7orf20-plk1 physical interaction xref: IntAct:EBI-731482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0006174 ! CG020_HUMAN [Term] id: CCO:I0008208 name: c9orf82-ptn physical interaction xref: IntAct:EBI-731497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006175 ! CI082_HUMAN [Term] id: CCO:I0008209 name: cacnb4-ptn physical interaction xref: IntAct:EBI-731503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006176 ! CACB4_HUMAN [Term] id: CCO:I0008210 name: cdh10-ptn physical interaction xref: IntAct:EBI-731530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006177 ! CAD10_HUMAN [Term] id: CCO:I0008211 name: cdk5rap2-ptn physical interaction xref: IntAct:EBI-731536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:I0008212 name: cdkn2b-ikbkap physical interaction xref: IntAct:EBI-731545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0005398 ! ELP1_HUMAN [Term] id: CCO:I0008213 name: cdkn2c-aplp1 physical interaction xref: IntAct:EBI-731551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0008214 name: cdkn2c-cops6 physical interaction xref: IntAct:EBI-731554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0008215 name: cdkn2c-gdf9 physical interaction xref: IntAct:EBI-731557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0008216 name: cox6c-ptn physical interaction xref: IntAct:EBI-731611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006181 ! COX6C_HUMAN [Term] id: CCO:I0008217 name: cradd-rif1 physical interaction xref: IntAct:EBI-731632 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006182 ! CRADD_HUMAN [Term] id: CCO:I0008218 name: ddx24-pin1 physical interaction xref: IntAct:EBI-731674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:I0008219 name: dleu1-psma1 physical interaction xref: IntAct:EBI-731695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN [Term] id: CCO:I0008220 name: dleu1-setdb1 physical interaction xref: IntAct:EBI-731698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0008221 name: dleu1-shmt1 physical interaction xref: IntAct:EBI-731701 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006184 ! GLYC_HUMAN [Term] id: CCO:I0008222 name: dleu1-tle1 physical interaction xref: IntAct:EBI-731704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0008223 name: dlst-dlg5 physical interaction xref: IntAct:EBI-731707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0006185 ! ODO2_HUMAN [Term] id: CCO:I0008224 name: dusp12-ptn physical interaction xref: IntAct:EBI-731758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006186 ! DUS12_HUMAN [Term] id: CCO:I0008225 name: egfl6-sh3gl3 physical interaction xref: IntAct:EBI-731773 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001947 ! EGFL6_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0008226 name: eif3s5-dkc1 physical interaction xref: IntAct:EBI-731788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001415 ! DKC1_HUMAN relationship: has_participant CCO:B0026277 ! EIF3F_HUMAN [Term] id: CCO:I0008227 name: ep300-cops6 physical interaction xref: IntAct:EBI-731824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0008230 name: erh-sh3gl2 physical interaction xref: IntAct:EBI-731845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001703 ! ERH_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0008231 name: ethe1-rif1 physical interaction xref: IntAct:EBI-731848 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006189 ! ETHE1_HUMAN [Term] id: CCO:I0008232 name: fgfr3-centd2 physical interaction xref: IntAct:EBI-731866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0008233 name: flj13391-ptn physical interaction xref: IntAct:EBI-731902 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0063411 ! F176A_HUMAN [Term] id: CCO:I0008234 name: flj20364-gps2 physical interaction xref: IntAct:EBI-731917 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0006191 ! CCD99_HUMAN [Term] id: CCO:I0008235 name: smpd3-med31 physical interaction xref: IntAct:EBI-731944 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0008236 name: smpd3-cops6 physical interaction xref: IntAct:EBI-731947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0008237 name: smpd3-crmp1 physical interaction xref: IntAct:EBI-731950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0008238 name: smpd3-dkfzp564o0523 physical interaction xref: IntAct:EBI-731953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0008239 name: smpd3-g22p1 physical interaction xref: IntAct:EBI-731956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0008240 name: smpd3-gdf9 physical interaction xref: IntAct:EBI-731959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0008241 name: smpd3-rif1 physical interaction xref: IntAct:EBI-731965 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN [Term] id: CCO:I0008242 name: smpd3-setdb1 physical interaction xref: IntAct:EBI-731968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0008243 name: ftl-ptn physical interaction xref: IntAct:EBI-731983 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006192 ! FRIL_HUMAN [Term] id: CCO:I0008244 name: gc-rif1 physical interaction xref: IntAct:EBI-732010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006193 ! VTDB_HUMAN [Term] id: CCO:I0008245 name: bloc1s1-ptn physical interaction xref: IntAct:EBI-732013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006194 ! BL1S1_HUMAN [Term] id: CCO:I0008246 name: glyat-ptn physical interaction xref: IntAct:EBI-732031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006195 ! GLYAT_HUMAN [Term] id: CCO:I0008247 name: gtf2f1-ptn physical interaction xref: IntAct:EBI-732091 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0005354 ! T2FA_HUMAN [Term] id: CCO:I0008248 name: hdac5-gabarap physical interaction xref: IntAct:EBI-732115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002244 ! HDAC5_HUMAN relationship: has_participant CCO:B0006196 ! GBRAP_HUMAN [Term] id: CCO:I0008249 name: hspb3-rif1 physical interaction xref: IntAct:EBI-732175 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006197 ! HSPB3_HUMAN [Term] id: CCO:I0008250 name: hspbp1-rif1 physical interaction xref: IntAct:EBI-732187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005199 ! HPBP1_HUMAN [Term] id: CCO:I0008251 name: ilf3-gdf9 physical interaction xref: IntAct:EBI-732235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0008252 name: itgb3bp-rif1 physical interaction xref: IntAct:EBI-732250 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:I0008253 name: itsn2-ptn physical interaction xref: IntAct:EBI-732279 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:I0008254 name: kibra-rif1 physical interaction xref: IntAct:EBI-732309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:I0008255 name: kif22-gdf9 physical interaction xref: IntAct:EBI-732315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001792 ! KIF22_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0008256 name: kif22-immt physical interaction xref: IntAct:EBI-732318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001792 ! KIF22_HUMAN relationship: has_participant CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:I0008257 name: kif22-pja1 physical interaction xref: IntAct:EBI-732321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001792 ! KIF22_HUMAN relationship: has_participant CCO:B0006202 ! PJA1_HUMAN [Term] id: CCO:I0008258 name: kntc2-tom1l1 physical interaction xref: IntAct:EBI-732324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0006203 ! TM1L1_HUMAN [Term] id: CCO:I0008259 name: lepr-pin1 physical interaction xref: IntAct:EBI-732336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0005902 ! LEPR_HUMAN [Term] id: CCO:I0008260 name: mad2l1bp-kiaa1377 physical interaction xref: IntAct:EBI-732407 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008261 name: mad2l1bp-igsf21 physical interaction xref: IntAct:EBI-732410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0008262 name: mad2l1bp-rif1 physical interaction xref: IntAct:EBI-732413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008263 name: maged1-plk1 physical interaction xref: IntAct:EBI-732431 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN [Term] id: CCO:I0008264 name: mcm2-rps4x physical interaction xref: IntAct:EBI-732464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001691 ! RS4X_HUMAN [Term] id: CCO:I0008265 name: c16orf24-tp53 physical interaction xref: IntAct:EBI-732491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0061994 ! F173A_HUMAN [Term] id: CCO:I0008266 name: mllt3-ptn physical interaction xref: IntAct:EBI-732527 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:I0008267 name: mllt3-rif1 physical interaction xref: IntAct:EBI-732530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:I0008268 name: mnat1-cops6 physical interaction xref: IntAct:EBI-732533 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0008269 name: mnat1-dkfzp564o0523 physical interaction xref: IntAct:EBI-732536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0008270 name: mnat1-eef1a1 physical interaction xref: IntAct:EBI-732539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0008271 name: mnat1-rif1 physical interaction xref: IntAct:EBI-732542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008272 name: mphosph6-aplp1 physical interaction xref: IntAct:EBI-732545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0008273 name: mphosph6-dkfzp564o05 physical interaction xref: IntAct:EBI-732548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0008274 name: mphosph6-gdf9 physical interaction xref: IntAct:EBI-732551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0008275 name: mpp3-mcm2 physical interaction xref: IntAct:EBI-732557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0006207 ! MPP3_HUMAN [Term] id: CCO:I0008276 name: mrps6-rif1 physical interaction xref: IntAct:EBI-732569 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006208 ! RT06_HUMAN [Term] id: CCO:I0008277 name: mycbp-ptn physical interaction xref: IntAct:EBI-732578 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN [Term] id: CCO:I0008278 name: nap1l5-ptn physical interaction xref: IntAct:EBI-732608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0063386 ! NP1L5_HUMAN [Term] id: CCO:I0008279 name: nasp-luc7l2 physical interaction xref: IntAct:EBI-732611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001626 ! NASP_HUMAN relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:I0008280 name: nhp2l1-g22p1 physical interaction xref: IntAct:EBI-732641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001676 ! NH2L1_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0008282 name: nhp2l1-pola2 physical interaction xref: IntAct:EBI-732647 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001676 ! NH2L1_HUMAN relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:I0008283 name: nhp2l1-rif1 physical interaction xref: IntAct:EBI-732650 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001676 ! NH2L1_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008284 name: paep-rif1 physical interaction xref: IntAct:EBI-732716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006212 ! PAEP_HUMAN [Term] id: CCO:I0008286 name: pfdn1-hip1 physical interaction xref: IntAct:EBI-732797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0006214 ! HIP1_HUMAN [Term] id: CCO:I0008287 name: pfdn1-immt physical interaction xref: IntAct:EBI-732800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:I0008288 name: pfdn1-psme1 physical interaction xref: IntAct:EBI-732803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0006215 ! PSME1_HUMAN [Term] id: CCO:I0008289 name: pfn1-dlg5 physical interaction xref: IntAct:EBI-732812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0006154 ! PROF1_HUMAN [Term] id: CCO:I0008290 name: plekha4-rif1 physical interaction xref: IntAct:EBI-732866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006216 ! PKHA4_HUMAN [Term] id: CCO:I0008291 name: pmf1-med31 physical interaction xref: IntAct:EBI-732878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0008292 name: pmf1-crmp1 physical interaction xref: IntAct:EBI-732881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0008293 name: pmf1-ptn physical interaction xref: IntAct:EBI-732884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0001912 ! PMF1_HUMAN [Term] id: CCO:I0008294 name: sept5-myst2 physical interaction xref: IntAct:EBI-732887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0008295 name: pold1-chgb physical interaction xref: IntAct:EBI-732896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:I0008296 name: pold1-kiaa1377 physical interaction xref: IntAct:EBI-732899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008297 name: ppp5c-cse1l physical interaction xref: IntAct:EBI-732935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001662 ! PPP5_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN [Term] id: CCO:I0008298 name: pqbp1-rif1 physical interaction xref: IntAct:EBI-732938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN [Term] id: CCO:I0008299 name: prei3-ube2v2 physical interaction xref: IntAct:EBI-732959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001813 ! UB2V2_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0008300 name: psmb10-ptn physical interaction xref: IntAct:EBI-732971 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006219 ! PSB10_HUMAN [Term] id: CCO:I0008301 name: pten-ang physical interaction xref: IntAct:EBI-733007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN [Term] id: CCO:I0008302 name: pten-chgb physical interaction xref: IntAct:EBI-733010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:I0008303 name: pten-cops6 physical interaction xref: IntAct:EBI-733013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0008304 name: pten-hba1 physical interaction xref: IntAct:EBI-733016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0006221 ! HBA_HUMAN [Term] id: CCO:I0008305 name: rab1a-cdkn1a physical interaction xref: IntAct:EBI-733058 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN [Term] id: CCO:I0008306 name: rab27a-rif1 physical interaction xref: IntAct:EBI-733079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006223 ! RB27A_HUMAN [Term] id: CCO:I0008307 name: ran-kiaa1377 physical interaction xref: IntAct:EBI-733094 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008308 name: recql5-plk1 physical interaction xref: IntAct:EBI-733100 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN [Term] id: CCO:I0008309 name: rgs2-arfgap1 physical interaction xref: IntAct:EBI-733121 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006225 ! ARFG1_HUMAN [Term] id: CCO:I0008310 name: rgs2-dncl1 physical interaction xref: IntAct:EBI-733124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006226 ! DYL1_HUMAN [Term] id: CCO:I0008311 name: rgs2-park2 physical interaction xref: IntAct:EBI-733127 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006227 ! PRKN2_HUMAN [Term] id: CCO:I0008312 name: rgs2-prkcsh physical interaction xref: IntAct:EBI-733130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006228 ! GLU2B_HUMAN [Term] id: CCO:I0008313 name: rit1-ptn physical interaction xref: IntAct:EBI-733133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN [Term] id: CCO:I0008314 name: rit1-rif1 physical interaction xref: IntAct:EBI-733136 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN [Term] id: CCO:I0008315 name: rnf10-rif1 physical interaction xref: IntAct:EBI-733142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006230 ! RNF10_HUMAN [Term] id: CCO:I0008316 name: rnpc4-ptn physical interaction xref: IntAct:EBI-733154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006106 ! Q6IA98_HUMAN [Term] id: CCO:I0008317 name: rpl37a-rif1 physical interaction xref: IntAct:EBI-733166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006231 ! RL37A_HUMAN [Term] id: CCO:I0008318 name: rrm1-rif1 physical interaction xref: IntAct:EBI-733190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006232 ! RIR1_HUMAN [Term] id: CCO:I0008319 name: s100a8-tp53 physical interaction xref: IntAct:EBI-733223 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006159 ! S10A8_HUMAN [Term] id: CCO:I0008320 name: pnn-pdpk1 physical interaction xref: IntAct:EBI-733277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002131 ! PININ_HUMAN relationship: has_participant CCO:B0006233 ! PDPK1_HUMAN [Term] id: CCO:I0008321 name: snapap-spag5 physical interaction xref: IntAct:EBI-733343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002058 ! SPAG5_HUMAN relationship: has_participant CCO:B0043870 ! SNAPN_HUMAN [Term] id: CCO:I0008322 name: sncaip-ptn physical interaction xref: IntAct:EBI-733346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006235 ! SNCAP_HUMAN [Term] id: CCO:I0008323 name: spg7-rif1 physical interaction xref: IntAct:EBI-733364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006236 ! SPG7_HUMAN [Term] id: CCO:I0008324 name: ssr1-dkc1 physical interaction xref: IntAct:EBI-733388 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001415 ! DKC1_HUMAN relationship: has_participant CCO:B0006163 ! SSRA_HUMAN [Term] id: CCO:I0008325 name: stc2-ptn physical interaction xref: IntAct:EBI-733394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006237 ! STC2_HUMAN [Term] id: CCO:I0008326 name: stx5a-rif1 physical interaction xref: IntAct:EBI-733418 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006164 ! STX5_HUMAN [Term] id: CCO:I0008327 name: supt5h-c9orf78 physical interaction xref: IntAct:EBI-733430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006238 ! Q6GVN4_HUMAN [Term] id: CCO:I0008328 name: supt5h-gtf3c1 physical interaction xref: IntAct:EBI-733433 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:I0008329 name: supt5h-ik physical interaction xref: IntAct:EBI-733436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006239 ! RED_HUMAN [Term] id: CCO:I0008330 name: supt5h-loc56902 physical interaction xref: IntAct:EBI-733439 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006240 ! PNO1_HUMAN [Term] id: CCO:I0008331 name: supt5h-phyhip physical interaction xref: IntAct:EBI-733442 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006241 ! PHYIP_HUMAN [Term] id: CCO:I0008332 name: supt5h-ppia physical interaction xref: IntAct:EBI-733445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006072 ! PPIA_HUMAN [Term] id: CCO:I0008333 name: tac3-ptn physical interaction xref: IntAct:EBI-733482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006242 ! TKNK_HUMAN [Term] id: CCO:I0008334 name: tada3l-hspa8 physical interaction xref: IntAct:EBI-733488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0008335 name: tada3l-rfx1 physical interaction xref: IntAct:EBI-733491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0006243 ! RFX1_HUMAN [Term] id: CCO:I0008336 name: tdgf1-rif1 physical interaction xref: IntAct:EBI-733517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN [Term] id: CCO:I0008337 name: terf1-utp14a physical interaction xref: IntAct:EBI-733520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0008338 name: terf1-tinf2 physical interaction xref: IntAct:EBI-733523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0006245 ! TINF2_HUMAN [Term] id: CCO:I0008339 name: tgif-rif1 physical interaction xref: IntAct:EBI-733538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006246 ! TGIF1_HUMAN [Term] id: CCO:I0008340 name: tm4sf6-rif1 physical interaction xref: IntAct:EBI-733565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006247 ! Q6IAN9_HUMAN [Term] id: CCO:I0008341 name: tnfrsf6-rif1 physical interaction xref: IntAct:EBI-733583 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN [Term] id: CCO:I0008342 name: pbk-kiaa1377 physical interaction xref: IntAct:EBI-733607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002045 ! TOPK_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008343 name: tp53bp2-mrpl20 physical interaction xref: IntAct:EBI-733610 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0006248 ! RM20_HUMAN [Term] id: CCO:I0008344 name: tpd52l1-c7orf36 physical interaction xref: IntAct:EBI-733613 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0006249 ! CG036_HUMAN [Term] id: CCO:I0008345 name: tpd52l1-eif3s1 physical interaction xref: IntAct:EBI-733616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0008346 name: trbv21_1-rif1 physical interaction xref: IntAct:EBI-733625 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006251 ! Q8N3Z8_HUMAN [Term] id: CCO:I0008348 name: ube1c-chd3 physical interaction xref: IntAct:EBI-733684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001989 ! UBA3_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0008349 name: ube2v2-rif1 physical interaction xref: IntAct:EBI-733687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001813 ! UB2V2_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008350 name: ulk2-nasp physical interaction xref: IntAct:EBI-733695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001626 ! NASP_HUMAN relationship: has_participant CCO:B0006252 ! ULK2_HUMAN [Term] id: CCO:I0008351 name: zcchc10-tp53 physical interaction xref: IntAct:EBI-733737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006253 ! ZCH10_HUMAN [Term] id: CCO:I0008352 name: znf7-tada3l physical interaction xref: IntAct:EBI-733746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0006254 ! ZNF7_HUMAN [Term] id: CCO:I0008353 name: klhlx-pin1 physical interaction xref: IntAct:EBI-733758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006170 ! Q5ZF45_HUMAN [Term] id: CCO:I0008354 name: apobec3g-ptn physical interaction xref: IntAct:EBI-733834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006255 ! ABC3G_HUMAN [Term] id: CCO:I0008355 name: arf4l-eml4 physical interaction xref: IntAct:EBI-733843 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002144 ! EMAL4_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN [Term] id: CCO:I0008356 name: arhgdia-cdkn1b physical interaction xref: IntAct:EBI-733864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN [Term] id: CCO:I0008357 name: arih2-eml4 physical interaction xref: IntAct:EBI-733873 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002144 ! EMAL4_HUMAN relationship: has_participant CCO:B0005288 ! ARI2_HUMAN [Term] id: CCO:I0008358 name: arpc3-centd2 physical interaction xref: IntAct:EBI-733895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN [Term] id: CCO:I0008359 name: arse-ndn physical interaction xref: IntAct:EBI-733919 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002075 ! NECD_HUMAN relationship: has_participant CCO:B0006258 ! ARSE_HUMAN [Term] id: CCO:I0008360 name: atp5c1-egfr physical interaction xref: IntAct:EBI-733962 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:I0008361 name: bcar1-e2f2 physical interaction xref: IntAct:EBI-734012 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001781 ! E2F2_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:I0008362 name: boc-rif1 physical interaction xref: IntAct:EBI-734021 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0006259 ! BOC_HUMAN [Term] id: CCO:I0008363 name: ubqln4-appbp1 physical interaction xref: IntAct:EBI-734060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0008364 name: c2f-khdrbs1 physical interaction xref: IntAct:EBI-734066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0006260 ! NEP1_HUMAN [Term] id: CCO:I0008365 name: c7orf20-cdkn1a physical interaction xref: IntAct:EBI-734078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0006174 ! CG020_HUMAN [Term] id: CCO:I0008366 name: calm1-mrpl20 physical interaction xref: IntAct:EBI-734102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0006248 ! RM20_HUMAN [Term] id: CCO:I0008367 name: calm1-myo6 physical interaction xref: IntAct:EBI-734105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:I0008368 name: cd81-dlg5 physical interaction xref: IntAct:EBI-734135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0006262 ! CD81_HUMAN [Term] id: CCO:I0008369 name: cdca5-g22p1 physical interaction xref: IntAct:EBI-734138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0008370 name: cdk5rap3-crmp1 physical interaction xref: IntAct:EBI-734145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002044 ! CK5P3_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0008371 name: cdkn1a-gnb2l1 physical interaction xref: IntAct:EBI-734149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0005739 ! GBLP_HUMAN [Term] id: CCO:I0008372 name: cdkn1a-hdac11 physical interaction xref: IntAct:EBI-734152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0005701 ! HDA11_HUMAN [Term] id: CCO:I0008373 name: centd2-g22p1 physical interaction xref: IntAct:EBI-734161 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0008374 name: cga-ptn physical interaction xref: IntAct:EBI-734164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006263 ! GLHA_HUMAN [Term] id: CCO:I0008375 name: chfr-eef1g physical interaction xref: IntAct:EBI-734167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0008376 name: cops7a-ppbp physical interaction xref: IntAct:EBI-734182 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006264 ! CSN7A_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008377 name: cox17-ppbp physical interaction xref: IntAct:EBI-734191 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006089 ! COX17_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008378 name: cugbp1-ppbp physical interaction xref: IntAct:EBI-734212 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006265 ! CELF1_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008379 name: cutl1-bin1 physical interaction xref: IntAct:EBI-734215 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001349 ! BIN1_HUMAN relationship: has_participant CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:I0008380 name: dfna5-ptn physical interaction xref: IntAct:EBI-734284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006267 ! DFNA5_HUMAN [Term] id: CCO:I0008381 name: dleu1-abcd4 physical interaction xref: IntAct:EBI-734338 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006268 ! ABCD4_HUMAN [Term] id: CCO:I0008382 name: dleu1-gdf9 physical interaction xref: IntAct:EBI-734344 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0008383 name: dnm2-bat1 physical interaction xref: IntAct:EBI-734365 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0005899 ! UAP56_HUMAN [Term] id: CCO:I0008384 name: efna1-ppbp physical interaction xref: IntAct:EBI-734406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006269 ! EFNA1_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008385 name: egfl6-sh3gl2 physical interaction xref: IntAct:EBI-734409 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001947 ! EGFL6_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0008386 name: eno2-ube2c physical interaction xref: IntAct:EBI-734442 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0006270 ! ENOG_HUMAN [Term] id: CCO:I0008387 name: fgfr3-flj22624 physical interaction xref: IntAct:EBI-734499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001914 ! BORA_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0008389 name: flj22624-fez1 physical interaction xref: IntAct:EBI-734587 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001914 ! BORA_HUMAN relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN [Term] id: CCO:I0008390 name: btbd10-dlg5 physical interaction xref: IntAct:EBI-734664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0006271 ! BTBDA_HUMAN [Term] id: CCO:I0008391 name: golgb1-brms1 physical interaction xref: IntAct:EBI-734673 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:I0008392 name: gpaa1-pin1 physical interaction xref: IntAct:EBI-734706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006273 ! GPAA1_HUMAN [Term] id: CCO:I0008393 name: gps2-golga2 physical interaction xref: IntAct:EBI-734709 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN [Term] id: CCO:I0008394 name: hdac5-eef1g physical interaction xref: IntAct:EBI-734748 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002244 ! HDAC5_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0008395 name: hmg20b-hnrpl physical interaction xref: IntAct:EBI-734760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002184 ! HM20B_HUMAN relationship: has_participant CCO:B0006275 ! HNRPL_HUMAN [Term] id: CCO:I0008396 name: hmg20b-tacc2 physical interaction xref: IntAct:EBI-734763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002184 ! HM20B_HUMAN relationship: has_participant CCO:B0006276 ! TACC2_HUMAN [Term] id: CCO:I0008397 name: hnrph3-pim2 physical interaction xref: IntAct:EBI-734778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0006277 ! HNRH3_HUMAN [Term] id: CCO:I0008398 name: hnrph3-rps4x physical interaction xref: IntAct:EBI-734781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001691 ! RS4X_HUMAN relationship: has_participant CCO:B0006277 ! HNRH3_HUMAN [Term] id: CCO:I0008400 name: kars-pafah1b1 physical interaction xref: IntAct:EBI-734890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0006279 ! SYK_HUMAN [Term] id: CCO:I0008401 name: kiaa0087-tp53 physical interaction xref: IntAct:EBI-734908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006280 ! K0087_HUMAN [Term] id: CCO:I0008402 name: klk10-rif1 physical interaction xref: IntAct:EBI-734929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001383 ! KLK10_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN [Term] id: CCO:I0008403 name: kif15-map1lc3a physical interaction xref: IntAct:EBI-734932 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002165 ! KIF15_HUMAN relationship: has_participant CCO:B0006281 ! MLP3A_HUMAN [Term] id: CCO:I0008404 name: lypla2-dkc1 physical interaction xref: IntAct:EBI-735022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001415 ! DKC1_HUMAN relationship: has_participant CCO:B0006282 ! LYPA2_HUMAN [Term] id: CCO:I0008405 name: mad2l1bp-trip13-1 physical interaction xref: IntAct:EBI-735031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0006283 ! TRP13_HUMAN [Term] id: CCO:I0008406 name: mkks-ptn physical interaction xref: IntAct:EBI-735130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006284 ! MKKS_HUMAN [Term] id: CCO:I0008407 name: mlf1-grik5 physical interaction xref: IntAct:EBI-735133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001684 ! MLF1_HUMAN relationship: has_participant CCO:B0006285 ! GRIK5_HUMAN [Term] id: CCO:I0008408 name: mnat1-hps6 physical interaction xref: IntAct:EBI-735136 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0006286 ! HPS6_HUMAN [Term] id: CCO:I0008409 name: mphosph6-c14orf1 physical interaction xref: IntAct:EBI-735139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0008410 name: mpp3-plk2 physical interaction xref: IntAct:EBI-735154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002179 ! PLK2_HUMAN relationship: has_participant CCO:B0006207 ! MPP3_HUMAN [Term] id: CCO:I0008411 name: mrps26-ppp2ca physical interaction xref: IntAct:EBI-735166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0006288 ! RT26_HUMAN [Term] id: CCO:I0008412 name: ndufb8-pim2 physical interaction xref: IntAct:EBI-735208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0006289 ! NDUB8_HUMAN [Term] id: CCO:I0008414 name: pafah1b2-pinx1 physical interaction xref: IntAct:EBI-735300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002033 ! PINX1_HUMAN relationship: has_participant CCO:B0006291 ! PA1B2_HUMAN [Term] id: CCO:I0008415 name: park2-rad1 physical interaction xref: IntAct:EBI-735321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001413 ! RAD1_HUMAN relationship: has_participant CCO:B0006227 ! PRKN2_HUMAN [Term] id: CCO:I0008416 name: phyhip-skb1 physical interaction xref: IntAct:EBI-735375 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001357 ! ANM5_HUMAN relationship: has_participant CCO:B0006241 ! PHYIP_HUMAN [Term] id: CCO:I0008417 name: plk2-ikbkap physical interaction xref: IntAct:EBI-735396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002179 ! PLK2_HUMAN relationship: has_participant CCO:B0005398 ! ELP1_HUMAN [Term] id: CCO:I0008418 name: plxnb2-ptn physical interaction xref: IntAct:EBI-735399 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006292 ! PLXB2_HUMAN [Term] id: CCO:I0008419 name: pmf1-gdf9 physical interaction xref: IntAct:EBI-735405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0008420 name: pmf1-kiaa1377 physical interaction xref: IntAct:EBI-735408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008421 name: ptd004-skb1 physical interaction xref: IntAct:EBI-735495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001357 ! ANM5_HUMAN relationship: has_participant CCO:B0006293 ! Q53SQ6_HUMAN [Term] id: CCO:I0008422 name: pten-utp14a physical interaction xref: IntAct:EBI-735498 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0008423 name: ptov1-pin1 physical interaction xref: IntAct:EBI-735507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006294 ! PTOV1_HUMAN [Term] id: CCO:I0008424 name: rab4a-tp53 physical interaction xref: IntAct:EBI-735569 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006295 ! RAB4A_HUMAN [Term] id: CCO:I0008425 name: rbbp4-g22p1 physical interaction xref: IntAct:EBI-735587 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0008426 name: recql5-mtss1 physical interaction xref: IntAct:EBI-735602 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN [Term] id: CCO:I0008427 name: rgs2-wdr74 physical interaction xref: IntAct:EBI-735614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006296 ! WDR74_HUMAN [Term] id: CCO:I0008429 name: rgs2-nipsnap1 physical interaction xref: IntAct:EBI-735620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006298 ! NIPS1_HUMAN [Term] id: CCO:I0008430 name: rgs2-vps29 physical interaction xref: IntAct:EBI-735623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006299 ! VPS29_HUMAN [Term] id: CCO:I0008431 name: rpl18a-mdk physical interaction xref: IntAct:EBI-735654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001544 ! MK_HUMAN relationship: has_participant CCO:B0006300 ! RL18A_HUMAN [Term] id: CCO:I0008432 name: ruvbl1-kiaa1377 physical interaction xref: IntAct:EBI-735705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0008433 name: supt7l-ptn physical interaction xref: IntAct:EBI-735875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006301 ! ST65G_HUMAN [Term] id: CCO:I0008434 name: supt5h-dbn1 physical interaction xref: IntAct:EBI-735938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:I0008435 name: tada3l-eif3s1 physical interaction xref: IntAct:EBI-735956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0008436 name: tcea2-rpa1 physical interaction xref: IntAct:EBI-735989 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0008437 name: terf1-capns1 physical interaction xref: IntAct:EBI-736004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN [Term] id: CCO:I0008438 name: terf1-dlg5 physical interaction xref: IntAct:EBI-736007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001993 ! DLG5_HUMAN [Term] id: CCO:I0008439 name: terf1-sh3gl3 physical interaction xref: IntAct:EBI-736013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0008440 name: thap8-tp53 physical interaction xref: IntAct:EBI-736031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0006304 ! THAP8_HUMAN [Term] id: CCO:I0008442 name: tp53bp2-usp4 physical interaction xref: IntAct:EBI-736082 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0006305 ! UBP4_HUMAN [Term] id: CCO:I0008443 name: tpd52l1-gpr135 physical interaction xref: IntAct:EBI-736088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0006306 ! GP135_HUMAN [Term] id: CCO:I0008444 name: tpd52l1-hdac1 physical interaction xref: IntAct:EBI-736091 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0008446 name: wfdc2-ptn physical interaction xref: IntAct:EBI-736184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006308 ! WFDC2_HUMAN [Term] id: CCO:I0008447 name: zcchc10-pin1 physical interaction xref: IntAct:EBI-736193 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006253 ! ZCH10_HUMAN [Term] id: CCO:I0008448 name: aurkb-tbl3 physical interaction xref: IntAct:EBI-736328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002040 ! AURKB_HUMAN relationship: has_participant CCO:B0006309 ! TBL3_HUMAN [Term] id: CCO:I0008449 name: axin1-sh3gl1 physical interaction xref: IntAct:EBI-736331 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN [Term] id: CCO:I0008450 name: brd4-chfr physical interaction xref: IntAct:EBI-736340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0006311 ! BRD4_HUMAN [Term] id: CCO:I0008451 name: c2f-nat6 physical interaction xref: IntAct:EBI-736391 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002026 ! NAT6_HUMAN relationship: has_participant CCO:B0006260 ! NEP1_HUMAN [Term] id: CCO:I0008452 name: c7orf20-ptms physical interaction xref: IntAct:EBI-736424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001539 ! PTMS_HUMAN relationship: has_participant CCO:B0006174 ! CG020_HUMAN [Term] id: CCO:I0008453 name: cdc2l1-c9orf74 physical interaction xref: IntAct:EBI-736457 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0006312 ! URM1_HUMAN [Term] id: CCO:I0008455 name: cdk5rap3-srprb physical interaction xref: IntAct:EBI-736469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002044 ! CK5P3_HUMAN relationship: has_participant CCO:B0006313 ! SRPRB_HUMAN [Term] id: CCO:I0008456 name: cdkn1a-flj20580 physical interaction xref: IntAct:EBI-736472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0006314 ! CA123_HUMAN [Term] id: CCO:I0008457 name: cdkn1a-itgb1bp3 physical interaction xref: IntAct:EBI-736475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0006315 ! NRK2_HUMAN [Term] id: CCO:I0008458 name: cdkn1a-slc25a11 physical interaction xref: IntAct:EBI-736478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0006316 ! M2OM_HUMAN [Term] id: CCO:I0008459 name: chfr-gabbr1 physical interaction xref: IntAct:EBI-736490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0006317 ! GABR1_HUMAN [Term] id: CCO:I0008460 name: chfr-itgae physical interaction xref: IntAct:EBI-736493 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0006318 ! ITAE_HUMAN [Term] id: CCO:I0008461 name: chfr-wdr47 physical interaction xref: IntAct:EBI-736496 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0006319 ! WDR47_HUMAN [Term] id: CCO:I0008462 name: css2-pin1 physical interaction xref: IntAct:EBI-736499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006320 ! CHSS2_HUMAN [Term] id: CCO:I0008463 name: mtfr1-pin1 physical interaction xref: IntAct:EBI-736502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0006321 ! MTFR1_HUMAN [Term] id: CCO:I0008464 name: csta-ptn physical interaction xref: IntAct:EBI-736526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0006322 ! CYTA_HUMAN [Term] id: CCO:I0008465 name: dbn1-nipbl physical interaction xref: IntAct:EBI-736538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001908 ! NIPBL_HUMAN relationship: has_participant CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:I0008466 name: dctn1-pgam1 physical interaction xref: IntAct:EBI-736541 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001779 ! DCTN1_HUMAN relationship: has_participant CCO:B0006323 ! PGAM1_HUMAN [Term] id: CCO:I0008467 name: dleu1-arl10c physical interaction xref: IntAct:EBI-736622 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0006324 ! ARL8B_HUMAN [Term] id: CCO:I0008468 name: dlgap4-plk2 physical interaction xref: IntAct:EBI-736625 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002179 ! PLK2_HUMAN relationship: has_participant CCO:B0006307 ! DLGP4_HUMAN [Term] id: CCO:I0008469 name: dmwd-ppbp physical interaction xref: IntAct:EBI-736631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001726 ! DMWD_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008470 name: dnm2-eif3s6ip physical interaction xref: IntAct:EBI-736643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0026279 ! IF3EI_HUMAN [Term] id: CCO:I0008471 name: dnm2-pef1 physical interaction xref: IntAct:EBI-736646 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0006326 ! PEF1_HUMAN [Term] id: CCO:I0008472 name: dnm2-ppib physical interaction xref: IntAct:EBI-736649 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0006327 ! PPIB_HUMAN [Term] id: CCO:I0008473 name: fbxo18-pim2 physical interaction xref: IntAct:EBI-736691 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0006328 ! FBX18_HUMAN [Term] id: CCO:I0008474 name: flj10415-aurkb physical interaction xref: IntAct:EBI-736706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002040 ! AURKB_HUMAN relationship: has_participant CCO:B0006329 ! ANKZ1_HUMAN [Term] id: CCO:I0008475 name: ftl-gadd45a physical interaction xref: IntAct:EBI-736787 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001552 ! GA45A_HUMAN relationship: has_participant CCO:B0006192 ! FRIL_HUMAN [Term] id: CCO:I0008476 name: fzr1-c7orf25 physical interaction xref: IntAct:EBI-736793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002229 ! FZR_HUMAN relationship: has_participant CCO:B0006330 ! CG025_HUMAN [Term] id: CCO:I0008477 name: fzr1-dnaja1 physical interaction xref: IntAct:EBI-736796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002229 ! FZR_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0008478 name: golph2-clk1 physical interaction xref: IntAct:EBI-736841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001632 ! CLK1_HUMAN relationship: has_participant CCO:B0006331 ! GOLM1_HUMAN [Term] id: CCO:I0008479 name: gps1-tbc1d17 physical interaction xref: IntAct:EBI-736880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001740 ! CSN1_HUMAN relationship: has_participant CCO:B0005279 ! TBC17_HUMAN [Term] id: CCO:I0008480 name: inpp1-lig1 physical interaction xref: IntAct:EBI-736952 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001534 ! DNLI1_HUMAN relationship: has_participant CCO:B0006332 ! INPP_HUMAN [Term] id: CCO:I0008481 name: kiaa0998-cdkn1a physical interaction xref: IntAct:EBI-736991 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0006333 ! TTLL5_HUMAN [Term] id: CCO:I0008482 name: lrpap1-ppm1g physical interaction xref: IntAct:EBI-737060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001375 ! PPM1G_HUMAN relationship: has_participant CCO:B0006334 ! AMRP_HUMAN [Term] id: CCO:I0008483 name: lrsam1-mutyh physical interaction xref: IntAct:EBI-737075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002205 ! MUTYH_HUMAN relationship: has_participant CCO:B0006335 ! LRSM1_HUMAN [Term] id: CCO:I0008484 name: mgc3731-cdk4 physical interaction xref: IntAct:EBI-737135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0006336 ! NOL12_HUMAN [Term] id: CCO:I0008485 name: mpz-pinx1 physical interaction xref: IntAct:EBI-737195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002033 ! PINX1_HUMAN relationship: has_participant CCO:B0006337 ! MYP0_HUMAN [Term] id: CCO:I0008487 name: pfdn1-c20orf39 physical interaction xref: IntAct:EBI-737324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0041279 ! TM90B_HUMAN [Term] id: CCO:I0008488 name: pfdn1-defa1 physical interaction xref: IntAct:EBI-737327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0006339 ! DEF1_HUMAN [Term] id: CCO:I0008489 name: pmaip1-ppbp physical interaction xref: IntAct:EBI-737384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006340 ! APR_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008490 name: pou3f3-ppp1r15a physical interaction xref: IntAct:EBI-737405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001436 ! PR15A_HUMAN relationship: has_participant CCO:B0006341 ! PO3F3_HUMAN [Term] id: CCO:I0008491 name: prei3-stk11 physical interaction xref: IntAct:EBI-737441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0008492 name: rab1a-mapre3 physical interaction xref: IntAct:EBI-737480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002238 ! MARE3_HUMAN relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN [Term] id: CCO:I0008493 name: rad1-map1lc3b physical interaction xref: IntAct:EBI-737510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001413 ! RAD1_HUMAN relationship: has_participant CCO:B0006342 ! MLP3B_HUMAN [Term] id: CCO:I0008494 name: ran-nefl physical interaction xref: IntAct:EBI-737516 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:I0008495 name: rassf1-nudt10 physical interaction xref: IntAct:EBI-737537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0006344 ! NUD10_HUMAN [Term] id: CCO:I0008496 name: rgs2-ctsb physical interaction xref: IntAct:EBI-737549 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006345 ! CATB_HUMAN [Term] id: CCO:I0008497 name: rgs2-scn5a physical interaction xref: IntAct:EBI-737552 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0006346 ! SCN5A_HUMAN [Term] id: CCO:I0008498 name: rint1-bnip3l physical interaction xref: IntAct:EBI-737555 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001909 ! RINT1_HUMAN relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:I0008499 name: rint1-sptbn1 physical interaction xref: IntAct:EBI-737558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001909 ! RINT1_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0008500 name: rint1-xpnpep1 physical interaction xref: IntAct:EBI-737561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001909 ! RINT1_HUMAN relationship: has_participant CCO:B0006347 ! XPP1_HUMAN [Term] id: CCO:I0008501 name: rpl21-pim2 physical interaction xref: IntAct:EBI-737594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0005862 ! RL21_HUMAN [Term] id: CCO:I0008502 name: rpn1-rbbp4 physical interaction xref: IntAct:EBI-737609 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0040688 ! RPN1_HUMAN [Term] id: CCO:I0008503 name: scfd1-ppbp physical interaction xref: IntAct:EBI-737645 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006349 ! SCFD1_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008504 name: pnn-vamp8 physical interaction xref: IntAct:EBI-737654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002131 ! PININ_HUMAN relationship: has_participant CCO:B0006350 ! VAMP8_HUMAN [Term] id: CCO:I0008505 name: sept3-wbp2 physical interaction xref: IntAct:EBI-737657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0002198 ! SEPT3_HUMAN relationship: has_participant CCO:B0006351 ! WBP2_HUMAN [Term] id: CCO:I0008506 name: spin-ptn physical interaction xref: IntAct:EBI-737696 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0002262 ! SPIN1_HUMAN [Term] id: CCO:I0008507 name: strn4-ppbp physical interaction xref: IntAct:EBI-737726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN [Term] id: CCO:I0008508 name: supt5h-h2afx physical interaction xref: IntAct:EBI-737741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN [Term] id: CCO:I0008509 name: supt5h-iqwd1 physical interaction xref: IntAct:EBI-737744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0006353 ! Q9P0U0_HUMAN [Term] id: CCO:I0008510 name: suv39h2-ube2v2 physical interaction xref: IntAct:EBI-737747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001813 ! UB2V2_HUMAN relationship: has_participant CCO:B0002139 ! SUV92_HUMAN [Term] id: CCO:I0008511 name: tada3l-adpgk physical interaction xref: IntAct:EBI-737753 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0006354 ! ADPGK_HUMAN [Term] id: CCO:I0008512 name: tada3l-c10orf45 physical interaction xref: IntAct:EBI-737756 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0006355 ! Q5T9K6_HUMAN [Term] id: CCO:I0008513 name: tubb4-lig1 physical interaction xref: IntAct:EBI-737816 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0001534 ! DNLI1_HUMAN relationship: has_participant CCO:B0006167 ! TBB4_HUMAN [Term] id: CCO:I0008518 name: ikbkg-ddb1 physical interaction xref: IntAct:EBI-361671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:I0008519 name: map3k1-ddb1 physical interaction xref: IntAct:EBI-361998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:I0008520 name: map3k3-ddb1 physical interaction xref: IntAct:EBI-362430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:I0008521 name: tnfrsf1b-ddb1 physical interaction xref: IntAct:EBI-364780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:I0008522 name: tle2-ddb1 physical interaction xref: IntAct:EBI-1176696 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN [Term] id: CCO:I0008523 name: ddb1-ddb2 physical interaction xref: IntAct:EBI-1177665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005658 ! DDB2_HUMAN [Term] id: CCO:I0008524 name: rbbp5-wdr5-1 physical interaction xref: IntAct:EBI-1177777 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN [Term] id: CCO:I0008525 name: l2dt1-ddb1 physical interaction xref: IntAct:EBI-1178616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:I0008526 name: eed-ddb1 physical interaction xref: IntAct:EBI-1178636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0043864 ! EED_HUMAN [Term] id: CCO:I0008527 name: ddb1-brap physical interaction comment: Interaction of DDB1 and BRAP identified by Y2H xref: IntAct:EBI-350213 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005471 ! BRAP_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN [Term] id: CCO:I0008528 name: ddb1-cops3 physical interaction comment: Interaction of DDB1 and COPS3 identified by Y2H xref: IntAct:EBI-350580 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0008529 name: cop1-ddb1 physical interaction xref: IntAct:EBI-1176618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0006001 ! RFWD2_HUMAN [Term] id: CCO:I0008530 name: l2dtl-ddb1 physical interaction xref: IntAct:EBI-1176630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN relationship: has_participant CCO:B0005687 ! GRWD1_HUMAN [Term] id: CCO:I0008531 name: wdr57-ddb1 physical interaction xref: IntAct:EBI-1176639 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005996 ! WDR57_HUMAN [Term] id: CCO:I0008532 name: wdr26-ddb1 physical interaction xref: IntAct:EBI-1176662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005689 ! WDR26_HUMAN [Term] id: CCO:I0008533 name: wdr5b-ddb1 physical interaction xref: IntAct:EBI-1176674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0006000 ! WDR5B_HUMAN [Term] id: CCO:I0008534 name: wdr5-ddb1 physical interaction xref: IntAct:EBI-1176685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0005615 ! WDR5_HUMAN [Term] id: CCO:I0008535 name: vamp3-ddb1 physical interaction xref: IntAct:EBI-737843 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0030751 ! VAMP3_HUMAN [Term] id: CCO:I0008542 name: chuk-myh10 physical interaction xref: IntAct:EBI-361179 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008543 name: ikbkb-myh10 physical interaction xref: IntAct:EBI-361257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008544 name: ikbke-myh10 physical interaction xref: IntAct:EBI-361323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008545 name: ikbkg-myh10 physical interaction xref: IntAct:EBI-361500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008546 name: map3k1-myh10 physical interaction xref: IntAct:EBI-361860 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008547 name: map3k3-myh10 physical interaction xref: IntAct:EBI-362205 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008548 name: ripk2-myh10 physical interaction xref: IntAct:EBI-363664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008550 name: tnfrsf1a-myh10 physical interaction xref: IntAct:EBI-364393 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008551 name: tnfrsf1b-myh10 physical interaction xref: IntAct:EBI-364636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:I0008552 name: strn4-asns physical interaction xref: IntAct:EBI-735893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0032819 ! ASNS_HUMAN [Term] id: CCO:I0008561 name: c9orf76-blm-4 colocalization comment: colocalization of BLAP75 and BLM xref: IntAct:EBI-624095 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:I0008562 name: blm-fen1-2 physical interaction comment: In vivo Co-IP: bait = FEN-1, prey = BLM xref: IntAct:EBI-708230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0008563 name: blm-fen1-4 physical interaction comment: In vivo Co-IP: bait = BLM, prey = FEN-1 xref: IntAct:EBI-708260 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0008564 name: menin-myh9-1 physical interaction comment: Interaction between human Menin and MYH9 detected by tandem affinity purification xref: IntAct:EBI-1136111 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:I0008565 name: c9orf76-blm-3 physical interaction comment: copurification: BLAP75 and BLM xref: IntAct:EBI-621454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005919 ! RMI1_HUMAN [Term] id: CCO:I0008566 name: wrn-blm-11 physical interaction comment: Pull-down using nuclear extracts: bait = WRM, prey = BLM xref: IntAct:EBI-707007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008567 name: menin-myh9-6 physical interaction comment: Cosedimentation of human Menin and MYH9 xref: IntAct:EBI-1148514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:I0008568 name: rrp4-rnf8 physical interaction xref: IntAct:EBI-373731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0035936 ! RNF8_HUMAN relationship: has_participant CCO:B0039757 ! EXOS2_HUMAN [Term] id: CCO:I0008569 name: mll-hcfc2-1 physical interaction comment: MLL associates wtih a cohort of proteins, as detected by affinity chromatography. xref: IntAct:EBI-592758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005486 ! HRX_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0036469 ! HCFC2_HUMAN relationship: has_participant CCO:B0039758 ! UTP18_HUMAN [Term] id: CCO:I0008570 name: wrn-blm-4 colocalization comment: Colocalization of WRN and BLM in human U2-OS cells xref: IntAct:EBI-706931 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008571 name: wrn-blm-6 direct interaction comment: Pull-down : bait = WRN, prey = BLM xref: IntAct:EBI-706961 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008572 name: wrn-blm-7 direct interaction comment: Pull-down : bait = WRN, prey = BLM xref: IntAct:EBI-706971 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008573 name: wrn-blm-9 direct interaction comment: Pull-down : bait = WRN, prey = BLM xref: IntAct:EBI-706989 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008574 name: wrn-blm-2 colocalization comment: Colocalization of WRN and BLM in human Hela cells xref: IntAct:EBI-706884 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008575 name: wrn-blm-5 physical interaction comment: In vivo Co-IP: bait = BLM, prey = WRN xref: IntAct:EBI-706943 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008576 name: menin-myh9-4 direct interaction comment: Interaction between human Menin and MYH9 detected by pulldown xref: IntAct:EBI-1140373 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:I0008577 name: myh9-menin-1 direct interaction comment: Interaction between human MYH9 and Menin detected by pulldown xref: IntAct:EBI-1141531 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:I0008578 name: wrn-blm-3 colocalization comment: Colocalization of WRN and BLM in WS cells xref: IntAct:EBI-706923 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008579 name: menin-myh9-3 physical interaction comment: Interaction between human Menin and MYH9 detected by coIP xref: IntAct:EBI-1139313 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:I0008580 name: blm-fen1-1 direct interaction comment: MBP pull-down: bait = BLM, prey = FEN-1 xref: IntAct:EBI-707913 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0008581 name: menin-myh9-2 physical interaction comment: Interaction between human Menin and MYH9 detected by tandem affinity purification xref: IntAct:EBI-1137776 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:I0008582 name: menin-myh9-5 colocalization comment: Colocalisation of human Menin and MYH9 detected by immunofluorescence microscopy xref: IntAct:EBI-1144664 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:I0008583 name: blm-fen1-3 direct interaction comment: ELISA: bait = BLM, probe = FEN-1 xref: IntAct:EBI-708251 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0008584 name: wrn-blm-1 direct interaction comment: ELISA: bait= WRN, probe=BLM xref: IntAct:EBI-706864 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:I0008654 name: ppp1r16a-fsd1 physical interaction xref: IntAct:EBI-735429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039949 ! FSD1_HUMAN relationship: has_participant CCO:B0039979 ! PP16A_HUMAN [Term] id: CCO:I0008655 name: nap1l1-fsd1 physical interaction xref: IntAct:EBI-737219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0039949 ! FSD1_HUMAN [Term] id: CCO:I0008675 name: cinp-cluap1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752512 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041266 ! CINP_HUMAN relationship: has_participant CCO:B0043416 ! CLUA1_HUMAN [Term] id: CCO:I0008676 name: trim39-ube2d1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019462 ! UB2D1_HUMAN relationship: has_participant CCO:B0043417 ! TRI39_HUMAN [Term] id: CCO:I0008677 name: psmc4-psmc5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753730 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041247 ! PRS6B_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN [Term] id: CCO:I0008678 name: ndp52-psma1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753919 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0008679 name: psme3-zcchc10 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754147 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006253 ! ZCH10_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008680 name: psma1-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754642 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN [Term] id: CCO:I0008681 name: nmi-psma1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755515 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0008682 name: rnf126-ube2d1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019462 ! UB2D1_HUMAN relationship: has_participant CCO:B0043418 ! RN126_HUMAN [Term] id: CCO:I0008683 name: bbs2-psme3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043419 ! BBS2_HUMAN [Term] id: CCO:I0008684 name: psme3-serf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043420 ! SERF2_HUMAN [Term] id: CCO:I0008685 name: psmc5-rora physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756745 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN [Term] id: CCO:I0008686 name: psma1-vim physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0008687 name: psmc5-tnnt1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041253 ! PRS8_HUMAN relationship: has_participant CCO:B0043421 ! TNNT1_HUMAN [Term] id: CCO:I0008688 name: psme3-psme3-1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757516 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008689 name: flj38984-psmc6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758299 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030905 ! PRS10_HUMAN relationship: has_participant CCO:B0043422 ! CA216_HUMAN [Term] id: CCO:I0008690 name: c12orf2-psmd4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041250 ! PSMD4_HUMAN relationship: has_participant CCO:B0043423 ! RASF8_HUMAN [Term] id: CCO:I0008691 name: psmc6-psmd9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758857 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030905 ! PRS10_HUMAN relationship: has_participant CCO:B0041239 ! PSMD9_HUMAN [Term] id: CCO:I0008692 name: kctd17-psma1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0043424 ! KCD17_HUMAN [Term] id: CCO:I0008693 name: itpkb-psme3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043425 ! IP3KB_HUMAN [Term] id: CCO:I0008694 name: krt15-psma1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN [Term] id: CCO:I0008695 name: btrc-trim9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759775 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0043426 ! TRIM9_HUMAN [Term] id: CCO:I0008696 name: krt15-psmc5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760000 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN [Term] id: CCO:I0008697 name: psmc2-psmd5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760210 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041246 ! PRS7_HUMAN relationship: has_participant CCO:B0041255 ! PSMD5_HUMAN [Term] id: CCO:I0008698 name: psme1-psme2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006215 ! PSME1_HUMAN relationship: has_participant CCO:B0043427 ! PSME2_HUMAN [Term] id: CCO:I0008699 name: psmc4-psmd10 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760255 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041240 ! PSD10_HUMAN relationship: has_participant CCO:B0041247 ! PRS6B_HUMAN [Term] id: CCO:I0008700 name: ncoa3-psme3-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-849865 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0008701 name: a2bp1-psmf1 physical interaction xref: IntAct:EBI-946332 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041263 ! PSMF1_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0008702 name: ncoa3-psme3 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-849837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0008703 name: nfkbie-psma5 physical interaction xref: IntAct:EBI-361059 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0022204 ! PSA5_HUMAN [Term] id: CCO:I0008704 name: nfkbie-psme3 physical interaction xref: IntAct:EBI-361152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008705 name: traf6-psmb6 physical interaction xref: IntAct:EBI-365107 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0031015 ! PSB6_HUMAN [Term] id: CCO:I0008706 name: traf6-psma4 physical interaction xref: IntAct:EBI-365143 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:I0008707 name: traf6-psmc6 physical interaction xref: IntAct:EBI-365149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0030905 ! PRS10_HUMAN [Term] id: CCO:I0008708 name: traf6-psmd4 physical interaction xref: IntAct:EBI-365152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0041250 ! PSMD4_HUMAN [Term] id: CCO:I0008709 name: traf6-psmc5 physical interaction xref: IntAct:EBI-365158 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN [Term] id: CCO:I0008710 name: traf6-psmb2 physical interaction xref: IntAct:EBI-365161 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0030800 ! PSB2_HUMAN [Term] id: CCO:I0008711 name: traf6-psma1 physical interaction xref: IntAct:EBI-365212 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0008712 name: traf6-psmd6 physical interaction xref: IntAct:EBI-365476 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0032651 ! PSMD6_HUMAN [Term] id: CCO:I0008713 name: traf6-psmb5 physical interaction xref: IntAct:EBI-365479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0030806 ! PSB5_HUMAN [Term] id: CCO:I0008714 name: traf6-psmc1 physical interaction xref: IntAct:EBI-365482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005314 ! PRS4_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0008715 name: traf6-psmc2 physical interaction xref: IntAct:EBI-365485 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0041246 ! PRS7_HUMAN [Term] id: CCO:I0008716 name: traf6-psmc3 physical interaction xref: IntAct:EBI-365488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0041242 ! PRS6A_HUMAN [Term] id: CCO:I0008717 name: traf6-psmd12 physical interaction xref: IntAct:EBI-365494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0038144 ! PSD12_HUMAN [Term] id: CCO:I0008718 name: traf6-psmd3 physical interaction xref: IntAct:EBI-365500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0021560 ! PSMD3_HUMAN [Term] id: CCO:I0008719 name: traf6-psmd7 physical interaction xref: IntAct:EBI-365503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0031003 ! PSD7_HUMAN [Term] id: CCO:I0008720 name: btrc-ctnnb1-1 physical interaction comment: Structure of a beta-trcp1-skp1-beta-catenin complex: destruction motif binding and lysine specificity on the scfbeta-trcp1 ubiquitin ligase xref: IntAct:EBI-1036687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN [Term] id: CCO:I0008721 name: lsm1-psmb8 physical interaction xref: IntAct:EBI-373848 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006005 ! LSM1_HUMAN relationship: has_participant CCO:B0030804 ! PSB8_HUMAN [Term] id: CCO:I0008722 name: lsm1-psmb5 physical interaction xref: IntAct:EBI-373854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006005 ! LSM1_HUMAN relationship: has_participant CCO:B0030806 ! PSB5_HUMAN [Term] id: CCO:I0008723 name: xrn2-psma3 physical interaction xref: IntAct:EBI-374109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:I0008724 name: alpha1-alpha2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 1 and alpha 2 xref: IntAct:EBI-696759 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:I0008725 name: alpha1-alpha7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 1 and alpha 7 xref: IntAct:EBI-696762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0030768 ! PSA7_HUMAN [Term] id: CCO:I0008726 name: alpha1-beta2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 1 and beta 2 xref: IntAct:EBI-696766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0030800 ! PSB2_HUMAN [Term] id: CCO:I0008727 name: alpha1-beta2i physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 1 and beta 2i xref: IntAct:EBI-696771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0006219 ! PSB10_HUMAN [Term] id: CCO:I0008728 name: alpha2-alpha1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 2 and alpha 1 xref: IntAct:EBI-696776 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:I0008729 name: alpha2-alpha4 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 2 and alpha 4 xref: IntAct:EBI-696779 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041243 ! PSA2_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:I0008730 name: alpha3-alpha4 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 3 and alpha 4 xref: IntAct:EBI-696817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:I0008731 name: alpha3-alpha2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 3 and alpha 2 xref: IntAct:EBI-696822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0041243 ! PSA2_HUMAN [Term] id: CCO:I0008732 name: alpha4-alpha3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 4 and alpha 3 xref: IntAct:EBI-696826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:I0008733 name: alpha4-alpha2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 4 and alpha 2 xref: IntAct:EBI-696830 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041243 ! PSA2_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:I0008734 name: alpha4-alpha7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 4 and alpha 7 xref: IntAct:EBI-696834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030768 ! PSA7_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:I0008735 name: alpha6-alpha2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 6 and alpha 2 xref: IntAct:EBI-696838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041243 ! PSA2_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:I0008736 name: alpha6-alpha7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 6 and alpha 7 xref: IntAct:EBI-696842 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030768 ! PSA7_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:I0008737 name: alpha7-alpha1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 7 and alpha 1 xref: IntAct:EBI-696846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0030768 ! PSA7_HUMAN [Term] id: CCO:I0008738 name: alpha7-alpha4 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 7 and alpha 4 xref: IntAct:EBI-696850 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030768 ! PSA7_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN [Term] id: CCO:I0008739 name: alpha7-alpha6 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits alpha 7 and alpha 6 xref: IntAct:EBI-696854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030768 ! PSA7_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:I0008740 name: beta2-beta3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 2 and beta 3 xref: IntAct:EBI-696858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030800 ! PSB2_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN [Term] id: CCO:I0008741 name: beta1-beta3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 1 and beta 3 xref: IntAct:EBI-696862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030929 ! PSB3_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN [Term] id: CCO:I0008742 name: beta1-beta7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 1 and beta 7 xref: IntAct:EBI-696866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030961 ! PSB1_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008743 name: beta1-beta5 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 1 and beta 5 xref: IntAct:EBI-696870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030806 ! PSB5_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN [Term] id: CCO:I0008744 name: beta1-beta5i physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 1 and beta 5i xref: IntAct:EBI-696891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030810 ! Q5JNW7_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN [Term] id: CCO:I0008745 name: beta1i-beta7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 1i and beta 7 xref: IntAct:EBI-696904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031007 ! PSB9_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008746 name: beta1i-beta5i physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 1i and beta 5i xref: IntAct:EBI-696909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030810 ! Q5JNW7_HUMAN relationship: has_participant CCO:B0031007 ! PSB9_HUMAN [Term] id: CCO:I0008747 name: beta2i-beta3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 2i and beta 3 xref: IntAct:EBI-696917 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006219 ! PSB10_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN [Term] id: CCO:I0008748 name: beta3-beta2i physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 3 and beta 2i xref: IntAct:EBI-696922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006219 ! PSB10_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN [Term] id: CCO:I0008749 name: beta3-beta2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 3 and beta 2 xref: IntAct:EBI-696925 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030800 ! PSB2_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN [Term] id: CCO:I0008750 name: beta5-beta1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 5 and beta 1 xref: IntAct:EBI-696929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030806 ! PSB5_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN [Term] id: CCO:I0008751 name: beta5-beta2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 5 and beta 2 xref: IntAct:EBI-696932 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030800 ! PSB2_HUMAN relationship: has_participant CCO:B0030806 ! PSB5_HUMAN [Term] id: CCO:I0008752 name: beta5-beta3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 5 and beta 3 xref: IntAct:EBI-696936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030806 ! PSB5_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN [Term] id: CCO:I0008753 name: beta5-alpha3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 5 and alpha 3 xref: IntAct:EBI-696940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0030806 ! PSB5_HUMAN [Term] id: CCO:I0008754 name: beta5-beta7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 5 and beta 7 xref: IntAct:EBI-696944 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030806 ! PSB5_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008755 name: beta5i-beta7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 5i and beta 7 xref: IntAct:EBI-696954 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030810 ! Q5JNW7_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008756 name: beta6-beta7 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 6 and beta 7 xref: IntAct:EBI-696958 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031015 ! PSB6_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008757 name: beta7-beta3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 7 and beta 3 xref: IntAct:EBI-696967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030929 ! PSB3_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008758 name: beta7-beta7 physical interaction comment: Directed yeast 2 hybrid analysis reveals homotypic interaction of the proteasome subunit beta 7 xref: IntAct:EBI-696972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008759 name: beta7-beta5i physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the proteasome subunits beta 7 and beta 5i xref: IntAct:EBI-696976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030810 ! Q5JNW7_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008760 name: dtnbp1-psme3 physical interaction xref: IntAct:EBI-1106252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008761 name: psma1-coil physical interaction xref: IntAct:EBI-955774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:I0008762 name: psme3-coil physical interaction xref: IntAct:EBI-955782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008763 name: psmc5-rora-1 physical interaction xref: IntAct:EBI-956038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN [Term] id: CCO:I0008764 name: atn1-psme3-2 physical interaction xref: IntAct:EBI-956430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008765 name: coil-psme3-1 physical interaction xref: IntAct:EBI-956646 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008766 name: psmf1-a2bp1 physical interaction xref: IntAct:EBI-956846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041263 ! PSMF1_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0008767 name: hrmt1l2-hmga2 physical interaction xref: IntAct:EBI-912570 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0041249 ! HMGA2_HUMAN [Term] id: CCO:I0008768 name: hrmt1l6-hmg2a physical interaction xref: IntAct:EBI-912646 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036272 ! ANM6_HUMAN relationship: has_participant CCO:B0041249 ! HMGA2_HUMAN [Term] id: CCO:I0008769 name: ncoa3-psme3-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-849846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0008770 name: hrmt1l6-hmga2 physical interaction xref: IntAct:EBI-912523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036272 ! ANM6_HUMAN relationship: has_participant CCO:B0041249 ! HMGA2_HUMAN [Term] id: CCO:I0008771 name: hsrma1-ube2e1 physical interaction xref: IntAct:EBI-348691 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041248 ! UB2E1_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0008772 name: bat2-psma3 physical interaction xref: IntAct:EBI-348883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005898 ! BAT2_HUMAN relationship: has_participant CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:I0008773 name: 20s proteasome-1 physical interaction comment: The 20S proteasome complex of human erythrocyte cells xref: IntAct:EBI-603379 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022204 ! PSA5_HUMAN relationship: has_participant CCO:B0030800 ! PSB2_HUMAN relationship: has_participant CCO:B0030806 ! PSB5_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN relationship: has_participant CCO:B0031015 ! PSB6_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN relationship: has_participant CCO:B0041243 ! PSA2_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN relationship: has_participant CCO:B0041245 ! PSB4_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:I0008774 name: fbxl7-skp1 physical interaction xref: IntAct:EBI-914675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043431 ! FBXL7_HUMAN [Term] id: CCO:I0008775 name: fbxl2-skp1 physical interaction xref: IntAct:EBI-914753 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043432 ! FBXW2_HUMAN [Term] id: CCO:I0008776 name: fbw5-skp1 physical interaction xref: IntAct:EBI-914761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043433 ! FBXW5_HUMAN [Term] id: CCO:I0008777 name: fbw6-skp1 physical interaction xref: IntAct:EBI-914791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043434 ! FBXW8_HUMAN [Term] id: CCO:I0008778 name: fbw7-skp1 physical interaction xref: IntAct:EBI-914799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0005654 ! FBXW7_HUMAN [Term] id: CCO:I0008779 name: fbxo41-skp1 physical interaction xref: IntAct:EBI-914816 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043435 ! FBX41_HUMAN [Term] id: CCO:I0008780 name: fbox11-skp1 physical interaction xref: IntAct:EBI-914839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0006051 ! JHD1A_HUMAN [Term] id: CCO:I0008781 name: atn1-psme3 physical interaction xref: IntAct:EBI-950920 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008782 name: atn1-psma3 physical interaction xref: IntAct:EBI-951046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:I0008783 name: atn1-psme3-1 physical interaction xref: IntAct:EBI-951052 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008784 name: atn1-psma3-1 physical interaction xref: IntAct:EBI-951184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:I0008785 name: atxn1-psmc3 physical interaction xref: IntAct:EBI-952324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0041242 ! PRS6A_HUMAN [Term] id: CCO:I0008786 name: coil-psme3 physical interaction xref: IntAct:EBI-952636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008787 name: prnp-psma3 physical interaction xref: IntAct:EBI-953386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0043436 ! PRIO_HUMAN [Term] id: CCO:I0008788 name: rere-psma3 physical interaction xref: IntAct:EBI-953422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0008789 name: rere-psma3-1 physical interaction xref: IntAct:EBI-953476 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0008790 name: ncoa3-psme3-3 direct interaction comment: Interaction detected by GST-pulldown. xref: IntAct:EBI-849878 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0008791 name: ncoa3-psme3-4 direct interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-849908 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0008792 name: psma3-psma6-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:I0008793 name: 20s proteasome physical interaction comment: The 20S proteasome complex of human U937 cells xref: IntAct:EBI-603360 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006219 ! PSB10_HUMAN relationship: has_participant CCO:B0022204 ! PSA5_HUMAN relationship: has_participant CCO:B0030800 ! PSB2_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN relationship: has_participant CCO:B0031015 ! PSB6_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN relationship: has_participant CCO:B0041243 ! PSA2_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN relationship: has_participant CCO:B0041245 ! PSB4_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:I0008794 name: itgb3bp-psme1 physical interaction xref: IntAct:EBI-728997 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0006215 ! PSME1_HUMAN [Term] id: CCO:I0008795 name: psma6-psma3 physical interaction xref: IntAct:EBI-729150 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN [Term] id: CCO:I0008796 name: psme1-chd3 physical interaction xref: IntAct:EBI-730627 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006215 ! PSME1_HUMAN [Term] id: CCO:I0008797 name: snrpf-psma3 physical interaction xref: IntAct:EBI-730864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0043438 ! RUXF_HUMAN [Term] id: CCO:I0008798 name: psme1-psme1 physical interaction xref: IntAct:EBI-732992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006215 ! PSME1_HUMAN [Term] id: CCO:I0008799 name: psme1-vcl physical interaction xref: IntAct:EBI-732995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006215 ! PSME1_HUMAN relationship: has_participant CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:I0008800 name: psme1-vim physical interaction xref: IntAct:EBI-732998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0006215 ! PSME1_HUMAN [Term] id: CCO:I0008801 name: psme3-hspa5 physical interaction xref: IntAct:EBI-733001 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008802 name: snrpb-psma3 physical interaction xref: IntAct:EBI-733352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0043440 ! RSMB_HUMAN [Term] id: CCO:I0008803 name: stx11-psma3 physical interaction xref: IntAct:EBI-733403 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005220 ! STX11_HUMAN relationship: has_participant CCO:B0005991 ! PSA3_HUMAN [Term] id: CCO:I0008804 name: ezh2-psmb6 physical interaction xref: IntAct:EBI-734460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031015 ! PSB6_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0008805 name: fbxo34-skp1a physical interaction xref: IntAct:EBI-734487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043442 ! FBX34_HUMAN [Term] id: CCO:I0008806 name: skp1a-fbxo34 physical interaction xref: IntAct:EBI-734490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043442 ! FBX34_HUMAN [Term] id: CCO:I0008807 name: psmd14-plekhb2 physical interaction xref: IntAct:EBI-735480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005569 ! PKHB2_HUMAN relationship: has_participant CCO:B0023606 ! PSDE_HUMAN [Term] id: CCO:I0008808 name: psme3-atp5b physical interaction xref: IntAct:EBI-735483 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005827 ! ATPB_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008809 name: psme3-centa1 physical interaction xref: IntAct:EBI-735486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0043443 ! CENA1_HUMAN [Term] id: CCO:I0008810 name: psme3-psme3 physical interaction xref: IntAct:EBI-735489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041252 ! PSME3_HUMAN [Term] id: CCO:I0008811 name: stx11-psmc3 physical interaction xref: IntAct:EBI-735923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005220 ! STX11_HUMAN relationship: has_participant CCO:B0041242 ! PRS6A_HUMAN [Term] id: CCO:I0008812 name: ube2e1-cbwd3 physical interaction xref: IntAct:EBI-736139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041248 ! UB2E1_HUMAN relationship: has_participant CCO:B0043444 ! CBWD3_HUMAN [Term] id: CCO:I0008813 name: ube2e1-paep physical interaction xref: IntAct:EBI-736142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006212 ! PAEP_HUMAN relationship: has_participant CCO:B0041248 ! UB2E1_HUMAN [Term] id: CCO:I0008814 name: usp22-hexa physical interaction xref: IntAct:EBI-736172 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024005 ! UBP22_HUMAN relationship: has_participant CCO:B0043445 ! HEXA_HUMAN [Term] id: CCO:I0008815 name: usp22-mrpl10 physical interaction xref: IntAct:EBI-736175 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024005 ! UBP22_HUMAN relationship: has_participant CCO:B0043446 ! RM10_HUMAN [Term] id: CCO:I0008816 name: usp22-psme1 physical interaction xref: IntAct:EBI-736178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006215 ! PSME1_HUMAN relationship: has_participant CCO:B0024005 ! UBP22_HUMAN [Term] id: CCO:I0008817 name: usp22-scfd1 physical interaction xref: IntAct:EBI-736181 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006349 ! SCFD1_HUMAN relationship: has_participant CCO:B0024005 ! UBP22_HUMAN [Term] id: CCO:I0008818 name: c2f-psmb7 physical interaction xref: IntAct:EBI-736397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006260 ! NEP1_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN [Term] id: CCO:I0008819 name: c2f-psme1 physical interaction xref: IntAct:EBI-736400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006215 ! PSME1_HUMAN relationship: has_participant CCO:B0006260 ! NEP1_HUMAN [Term] id: CCO:I0008820 name: ddx19b-skp1a physical interaction xref: IntAct:EBI-736565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0043447 ! DD19B_HUMAN [Term] id: CCO:I0008821 name: mrps9-ccndbp1 physical interaction xref: IntAct:EBI-737207 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041241 ! CCDB1_HUMAN relationship: has_participant CCO:B0043448 ! RT09_HUMAN [Term] id: CCO:I0008822 name: psmd14-flj10324 physical interaction xref: IntAct:EBI-737462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023606 ! PSDE_HUMAN relationship: has_participant CCO:B0043449 ! Q75LH2_HUMAN [Term] id: CCO:I0008823 name: psmd14-rbm15b physical interaction xref: IntAct:EBI-737465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023606 ! PSDE_HUMAN relationship: has_participant CCO:B0043450 ! RB15B_HUMAN [Term] id: CCO:I0008824 name: rab1a-psmd7 physical interaction xref: IntAct:EBI-737483 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0031003 ! PSD7_HUMAN [Term] id: CCO:I0008959 name: ewsr1-rps15a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN [Term] id: CCO:I0008960 name: elf5-rps15a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043825 ! RS15A_HUMAN relationship: has_participant CCO:B0059208 ! ELF5_HUMAN [Term] id: CCO:I0008961 name: smad3-zfyve9-1 direct interaction comment: Smad3 sbd complex xref: IntAct:EBI-1034043 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0054758 ! ZFYV9_HUMAN [Term] id: CCO:I0008962 name: smad3-sry-3 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005205 ! IL1F5_HUMAN relationship: has_participant CCO:B0006212 ! PAEP_HUMAN relationship: has_participant CCO:B0020282 ! SRY_HUMAN relationship: has_participant CCO:B0023715 ! K1C10_HUMAN relationship: has_participant CCO:B0026523 ! GDE_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0061985 ! JPH1_HUMAN [Term] id: CCO:I0008963 name: ikbkg-rps15a physical interaction xref: IntAct:EBI-361704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN [Term] id: CCO:I0008964 name: nfkb2-rps15a physical interaction xref: IntAct:EBI-362905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN [Term] id: CCO:I0008965 name: map3k14-rps15a physical interaction xref: IntAct:EBI-363190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN [Term] id: CCO:I0008966 name: ifng-ifngr1-1 direct interaction comment: 1:1 complex between an interferon gamma single-chain variant and its receptor xref: IntAct:EBI-1030783 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0055033 ! INGR1_HUMAN [Term] id: CCO:I0008967 name: edn1-ubqln4 physical interaction xref: IntAct:EBI-954838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN [Term] id: CCO:I0008968 name: smad3-sry physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-464983 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020282 ! SRY_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:I0008969 name: smad3-sry-2 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-464999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020282 ! SRY_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:I0008970 name: smad3-actb physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:I0008971 name: smad-actb-2 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:I0008972 name: smad3-prtn3 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0055168 ! PRTN3_HUMAN [Term] id: CCO:I0008973 name: smad3-prtn3-2 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0055168 ! PRTN3_HUMAN [Term] id: CCO:I0008974 name: smad3-actb-2 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465050 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:I0008975 name: smad3-srebf2 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465071 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0049934 ! SRBP2_HUMAN [Term] id: CCO:I0008976 name: smad3-srebf2-1 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0049934 ! SRBP2_HUMAN [Term] id: CCO:I0008977 name: smad3-srebf2-2 physical interaction comment: Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity xref: IntAct:EBI-465084 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0049934 ! SRBP2_HUMAN [Term] id: CCO:I0008978 name: ski-madh3-1 physical interaction xref: IntAct:EBI-347288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0055004 ! SKI_HUMAN [Term] id: CCO:I0008979 name: dach- madh3-1 physical interaction xref: IntAct:EBI-347215 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:I0008980 name: bat1-rps15a physical interaction xref: IntAct:EBI-348928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005899 ! UAP56_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN [Term] id: CCO:I0008981 name: il12a-il12b-1 direct interaction comment: Human interleukin-12 xref: IntAct:EBI-1029655 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0061988 ! IL12A_HUMAN [Term] id: CCO:I0008982 name: smad3-smad4-1 direct interaction comment: Crystal structure of the phosphorylated smad3-smad4 heterotrimeric complex xref: IntAct:EBI-1040178 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN [Term] id: CCO:I0008983 name: edn1-cops6 physical interaction xref: IntAct:EBI-731764 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN [Term] id: CCO:I0008984 name: edn1-bat3 physical interaction xref: IntAct:EBI-734397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN [Term] id: CCO:I0014951 name: gorasp2-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:I0014952 name: ewsr1-hhgp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0032831 ! PRDC1_HUMAN [Term] id: CCO:I0014953 name: mageh1-moap1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005406 ! MAGH1_HUMAN relationship: has_participant CCO:B0021834 ! MOAP1_HUMAN [Term] id: CCO:I0014954 name: kiaa1838-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752533 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0058207 ! F120B_HUMAN [Term] id: CCO:I0014955 name: traf2-zbtb25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0055169 ! ZBT25_HUMAN [Term] id: CCO:I0014956 name: c1orf149-l3mbtl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0049761 ! CA149_HUMAN relationship: has_participant CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:I0014957 name: trip10-wbp11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005313 ! WBP11_HUMAN relationship: has_participant CCO:B0056090 ! CIP4_HUMAN [Term] id: CCO:I0014958 name: c21orf6-gadd45g physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0062767 ! RWD2B_HUMAN [Term] id: CCO:I0014959 name: ribc2-trim23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005240 ! RIBC2_HUMAN relationship: has_participant CCO:B0055308 ! ARD1_HUMAN [Term] id: CCO:I0014960 name: pdcd10-stk24 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752587 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022743 ! STK24_HUMAN relationship: has_participant CCO:B0062768 ! PDC10_HUMAN [Term] id: CCO:I0014961 name: exoc7-hgs physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0062769 ! EXOC7_HUMAN [Term] id: CCO:I0014962 name: znf435-znf446 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN relationship: has_participant CCO:B0049842 ! ZSC16_HUMAN [Term] id: CCO:I0014963 name: ewsr1-zdhhc3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062770 ! ZDHC3_HUMAN [Term] id: CCO:I0014964 name: fbxo28-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062771 ! FBX28_HUMAN [Term] id: CCO:I0014965 name: ddx19a-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062772 ! DD19A_HUMAN [Term] id: CCO:I0014966 name: ewsr1-msc physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752632 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0054575 ! MUSC_HUMAN [Term] id: CCO:I0014967 name: dtx2-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0014968 name: grap2-zbtb7b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752653 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054411 ! ZBT7B_HUMAN relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN [Term] id: CCO:I0014969 name: rbpms-tollip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752656 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN [Term] id: CCO:I0014970 name: itm2c-rnf7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059071 ! RBX2_HUMAN relationship: has_participant CCO:B0062773 ! ITM2C_HUMAN [Term] id: CCO:I0014971 name: krtap4_12-otx1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0055254 ! OTX1_HUMAN [Term] id: CCO:I0014972 name: ewsr1-mgc34821 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062774 ! S22AO_HUMAN [Term] id: CCO:I0014973 name: hmg20a-tesc physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752692 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005296 ! HM20A_HUMAN relationship: has_participant CCO:B0062775 ! TESC_HUMAN [Term] id: CCO:I0014974 name: dydc1-nme5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055546 ! NDK5_HUMAN relationship: has_participant CCO:B0062776 ! DYDC1_HUMAN [Term] id: CCO:I0014975 name: arhgef15-prei3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0029042 ! ARHGF_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0014976 name: znf297b-znf417 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752713 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054468 ! ZBT43_HUMAN relationship: has_participant CCO:B0057893 ! ZN417_HUMAN [Term] id: CCO:I0014977 name: ldoc1-lnx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0005305 ! LNX1_HUMAN [Term] id: CCO:I0014978 name: cldn7-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0049698 ! CLD7_HUMAN [Term] id: CCO:I0014979 name: flj11016-hnrpk physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0062777 ! RBM41_HUMAN [Term] id: CCO:I0014980 name: myst2-vim physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0014981 name: hoxa1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0014982 name: plscr1-rasd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0059295 ! RASD1_HUMAN [Term] id: CCO:I0014983 name: krt15-smarcd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN [Term] id: CCO:I0014984 name: dvl2-pcbd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:I0014985 name: aasdhppt-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062778 ! ADPPT_HUMAN [Term] id: CCO:I0014986 name: birc2-magea11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752776 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN [Term] id: CCO:I0014987 name: l3mbtl2-phf10 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057976 ! PHF10_HUMAN relationship: has_participant CCO:B0058140 ! LMBL2_HUMAN [Term] id: CCO:I0014988 name: dtx2-vsnl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005986 ! VISL1_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0014989 name: dnmt3l-phpt1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037714 ! DNM3L_HUMAN relationship: has_participant CCO:B0062779 ! PHP14_HUMAN [Term] id: CCO:I0014990 name: nol3-nol3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054591 ! NOL3_HUMAN [Term] id: CCO:I0014991 name: fzd9-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0038866 ! Q8TAN2_HUMAN [Term] id: CCO:I0014992 name: trim23-trim23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055308 ! ARD1_HUMAN [Term] id: CCO:I0014993 name: pcbd1-pcbd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752827 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:I0014994 name: nup54-nup62 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0062780 ! NUP54_HUMAN [Term] id: CCO:I0014995 name: gabarapl2-mlx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0051349 ! GBRL2_HUMAN relationship: has_participant CCO:B0059130 ! MLX_HUMAN [Term] id: CCO:I0014996 name: hhgp-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752851 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0032831 ! PRDC1_HUMAN [Term] id: CCO:I0014997 name: dvl2-usp5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005310 ! UBP5_HUMAN [Term] id: CCO:I0014998 name: cry1-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0056142 ! CRY1_HUMAN [Term] id: CCO:I0014999 name: hoxb6-sat physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006107 ! SAT1_HUMAN relationship: has_participant CCO:B0036826 ! HXB6_HUMAN [Term] id: CCO:I0015000 name: pepp2-rbm11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0023760 ! RBM11_HUMAN [Term] id: CCO:I0015001 name: fkhl18-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0049072 ! FOXS1_HUMAN [Term] id: CCO:I0015002 name: loc541468-thap7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058511 ! THAP7_HUMAN relationship: has_participant CCO:B0062781 ! CA190_HUMAN [Term] id: CCO:I0015003 name: mgc14817-nfic physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025412 ! NFIC_HUMAN relationship: has_participant CCO:B0062782 ! CL031_HUMAN [Term] id: CCO:I0015004 name: c12orf11-znf655 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058476 ! Q9BQ85_HUMAN relationship: has_participant CCO:B0062783 ! CL011_HUMAN [Term] id: CCO:I0015005 name: dtx2-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0015006 name: chic2-top3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020052 ! CHIC2_HUMAN relationship: has_participant CCO:B0054815 ! TOP3B_HUMAN [Term] id: CCO:I0015007 name: baz2b-ctbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752962 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN relationship: has_participant CCO:B0059159 ! BAZ2B_HUMAN [Term] id: CCO:I0015008 name: magea11-mxd3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752965 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0058529 ! MAD3_HUMAN [Term] id: CCO:I0015009 name: hebp2-pdcd6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752974 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054618 ! PDCD6_HUMAN relationship: has_participant CCO:B0062784 ! HEBP2_HUMAN [Term] id: CCO:I0015010 name: cnksr1-pscd3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054516 ! CYH3_HUMAN relationship: has_participant CCO:B0058131 ! CNKR1_HUMAN [Term] id: CCO:I0015011 name: tceb3b-znf165 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-752998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055441 ! ZN165_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015012 name: c12orf2-frmd6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005267 ! FRMD6_HUMAN relationship: has_participant CCO:B0043423 ! RASF8_HUMAN [Term] id: CCO:I0015013 name: dvl2-poli physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0059249 ! POLI_HUMAN [Term] id: CCO:I0015014 name: ewsr1-myo1f physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0040367 ! MYO1F_HUMAN [Term] id: CCO:I0015015 name: cep70-myst2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0062785 ! CEP70_HUMAN [Term] id: CCO:I0015016 name: ewsr1-mgc2749 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005184 ! CS050_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0015017 name: eps8-pldn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005183 ! PLDN_HUMAN relationship: has_participant CCO:B0019772 ! EPS8_HUMAN [Term] id: CCO:I0015018 name: nif3l1-vim physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753058 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0015019 name: drap1-nfyb physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753061 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0015020 name: hoxa1-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0015021 name: ldoc1-poll physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0058515 ! Q9BTN8_HUMAN [Term] id: CCO:I0015022 name: dtnb-nup62 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0030221 ! Q96AW0_HUMAN [Term] id: CCO:I0015023 name: c1orf117-dnaja3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753100 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005290 ! F131C_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0015024 name: dhps-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753103 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0055423 ! DHYS_HUMAN [Term] id: CCO:I0015025 name: pepp2-vps25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753106 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0058490 ! VPS25_HUMAN [Term] id: CCO:I0015026 name: cep63-mbip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0005590 ! CEP63_HUMAN [Term] id: CCO:I0015027 name: tceb3b-trim37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015028 name: abi3-dtnbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753121 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN relationship: has_participant CCO:B0038093 ! ABI3_HUMAN [Term] id: CCO:I0015029 name: khdrbs3-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015030 name: ddit4l-snrpg physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005495 ! RUXG_HUMAN relationship: has_participant CCO:B0058188 ! DDT4L_HUMAN [Term] id: CCO:I0015031 name: c18orf56-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062786 ! CR056_HUMAN [Term] id: CCO:I0015032 name: creb3-stx8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0062787 ! STX8_HUMAN [Term] id: CCO:I0015033 name: wwp1-znf638 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753175 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058653 ! WWP1_HUMAN relationship: has_participant CCO:B0062788 ! ZN638_HUMAN [Term] id: CCO:I0015034 name: exoc8-tada2l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753181 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005255 ! EXOC8_HUMAN relationship: has_participant CCO:B0005318 ! Q9BVJ0_HUMAN [Term] id: CCO:I0015035 name: btg1-cnot8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050534 ! CNOT8_HUMAN relationship: has_participant CCO:B0055615 ! BTG1_HUMAN [Term] id: CCO:I0015036 name: hoxa9-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753193 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0055236 ! HXA9_HUMAN [Term] id: CCO:I0015037 name: gabarapl2-tbc1d5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0051349 ! GBRL2_HUMAN relationship: has_participant CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:I0015038 name: mmtag2-sdcbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058662 ! SDCB2_HUMAN relationship: has_participant CCO:B0062789 ! MMTA2_HUMAN [Term] id: CCO:I0015039 name: pepp2-plod3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0062790 ! PLOD3_HUMAN [Term] id: CCO:I0015040 name: necap2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753247 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062791 ! NECP2_HUMAN [Term] id: CCO:I0015041 name: rfx3-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0028073 ! RFX3_HUMAN [Term] id: CCO:I0015042 name: gabarapl2-sqstm1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0051349 ! GBRL2_HUMAN relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:I0015043 name: gadd45g-tsnax physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0062792 ! TSNAX_HUMAN [Term] id: CCO:I0015044 name: gga2-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753289 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005200 ! GGA2_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015045 name: bahd1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062793 ! BAHD1_HUMAN [Term] id: CCO:I0015046 name: pde9a-trim32 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054693 ! PDE9A_HUMAN relationship: has_participant CCO:B0062794 ! TRI32_HUMAN [Term] id: CCO:I0015047 name: c1orf165-grap2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN relationship: has_participant CCO:B0062795 ! CA165_HUMAN [Term] id: CCO:I0015048 name: dkk1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0054709 ! DKK1_HUMAN [Term] id: CCO:I0015049 name: ccdc7-wdr39 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019119 ! CCDC7_HUMAN relationship: has_participant CCO:B0054691 ! CIAO1_HUMAN [Term] id: CCO:I0015050 name: armc7-kctd13 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753361 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058049 ! KCD13_HUMAN relationship: has_participant CCO:B0062796 ! ARMC7_HUMAN [Term] id: CCO:I0015051 name: c6orf166-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753367 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058995 ! SPG21_HUMAN relationship: has_participant CCO:B0062797 ! AKIR2_HUMAN [Term] id: CCO:I0015052 name: ebi3-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753382 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0055972 ! IL27B_HUMAN [Term] id: CCO:I0015053 name: bambi-sox30 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753388 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020266 ! SOX30_HUMAN relationship: has_participant CCO:B0062798 ! BAMBI_HUMAN [Term] id: CCO:I0015054 name: cnot2-cnot3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0049757 ! CNOT2_HUMAN relationship: has_participant CCO:B0054611 ! CNOT3_HUMAN [Term] id: CCO:I0015055 name: mdfi-znf426 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753433 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0058524 ! ZN426_HUMAN [Term] id: CCO:I0015056 name: pepp2-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0015057 name: arrb1-znf297b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054468 ! ZBT43_HUMAN relationship: has_participant CCO:B0055424 ! ARRB1_HUMAN [Term] id: CCO:I0015058 name: c18orf45-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062799 ! Q9BRG3_HUMAN [Term] id: CCO:I0015059 name: abi3-runx1t1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038093 ! ABI3_HUMAN relationship: has_participant CCO:B0055769 ! MTG8_HUMAN [Term] id: CCO:I0015060 name: pepp2-tollip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0015061 name: drr1-efemp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015062 name: myst2-znf165 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015063 name: flj10094-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062800 ! ENOX1_HUMAN [Term] id: CCO:I0015064 name: birc4-c8orf32 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005179 ! CH032_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0015065 name: bahd1-khdrbs3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN relationship: has_participant CCO:B0062793 ! BAHD1_HUMAN [Term] id: CCO:I0015066 name: ewsr1-hcg3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062801 ! Q8WWF6_HUMAN [Term] id: CCO:I0015067 name: frmd6-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005267 ! FRMD6_HUMAN [Term] id: CCO:I0015068 name: abi2-vcl physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753547 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038095 ! ABI2_HUMAN relationship: has_participant CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:I0015069 name: ewsr1-fasn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:I0015070 name: apex2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062803 ! APEX2_HUMAN [Term] id: CCO:I0015071 name: magea11-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015072 name: krtap4_12-pnkp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753577 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:I0015073 name: mdfi-six1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753580 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0056069 ! SIX1_HUMAN [Term] id: CCO:I0015074 name: s100a1-s100p physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753583 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055155 ! S10A1_HUMAN relationship: has_participant CCO:B0062804 ! S100P_HUMAN [Term] id: CCO:I0015075 name: appbp2-cntfr physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026846 ! CNTFR_HUMAN relationship: has_participant CCO:B0062805 ! APBP2_HUMAN [Term] id: CCO:I0015076 name: nfic-zcchc14 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025412 ! NFIC_HUMAN relationship: has_participant CCO:B0062806 ! Q96HZ8_HUMAN [Term] id: CCO:I0015077 name: pom121-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0061984 ! P121A_HUMAN [Term] id: CCO:I0015078 name: ewsr1-nle1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0050490 ! NLE1_HUMAN [Term] id: CCO:I0015079 name: chic2-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0020052 ! CHIC2_HUMAN [Term] id: CCO:I0015080 name: nfic-znf167 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025412 ! NFIC_HUMAN relationship: has_participant CCO:B0059030 ! ZN167_HUMAN [Term] id: CCO:I0015081 name: c9orf65-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0021588 ! PRUN2_HUMAN [Term] id: CCO:I0015082 name: ndp52-pias4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753673 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0015083 name: znf446-znf496 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN relationship: has_participant CCO:B0058233 ! ZN496_HUMAN [Term] id: CCO:I0015084 name: ewsr1-wwp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062807 ! WWP2_HUMAN [Term] id: CCO:I0015085 name: mdfi-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0015086 name: stx11-taf6l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005220 ! STX11_HUMAN relationship: has_participant CCO:B0023501 ! TAF6L_HUMAN [Term] id: CCO:I0015087 name: tceb3b-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753724 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015088 name: set-thap7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753739 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005519 ! SET_HUMAN relationship: has_participant CCO:B0058511 ! THAP7_HUMAN [Term] id: CCO:I0015089 name: cgi_128-wdr39 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753748 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038937 ! FA96B_HUMAN relationship: has_participant CCO:B0054691 ! CIAO1_HUMAN [Term] id: CCO:I0015090 name: grap2-hnrpk physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN [Term] id: CCO:I0015091 name: ppfibp2-tsg101 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0037978 ! LIPB2_HUMAN [Term] id: CCO:I0015092 name: spata2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753769 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062808 ! SPAT2_HUMAN [Term] id: CCO:I0015093 name: hook2-myst2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0062809 ! HOOK2_HUMAN [Term] id: CCO:I0015094 name: nif3l1-zbed1x physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753784 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005231 ! ZBED1_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015095 name: hnrpk-hnrpk physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN [Term] id: CCO:I0015096 name: c16orf48-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0062810 ! CP048_HUMAN [Term] id: CCO:I0015097 name: gem-trim23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753805 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055308 ! ARD1_HUMAN relationship: has_participant CCO:B0055523 ! GEM_HUMAN [Term] id: CCO:I0015098 name: krtap4_12-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0055041 ! ZN250_HUMAN [Term] id: CCO:I0015099 name: appbp2-c1orf166 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753823 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058142 ! MUL1_HUMAN relationship: has_participant CCO:B0062805 ! APBP2_HUMAN [Term] id: CCO:I0015100 name: drr1-trim37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015101 name: cdc42ep1-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753829 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:I0015102 name: actn1-xrcc4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005651 ! XRCC4_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0015103 name: mbip-mbip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN [Term] id: CCO:I0015104 name: lrch4-rtn4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753853 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0054634 ! LRCH4_HUMAN [Term] id: CCO:I0015105 name: cova1-magea11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753859 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0056127 ! ENOX2_HUMAN [Term] id: CCO:I0015106 name: dazap2-poli physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0059249 ! POLI_HUMAN [Term] id: CCO:I0015107 name: ewsr1-ndufb1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062811 ! NDUB1_HUMAN [Term] id: CCO:I0015108 name: lpxn-znf426 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753886 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017845 ! LPXN_HUMAN relationship: has_participant CCO:B0058524 ! ZN426_HUMAN [Term] id: CCO:I0015109 name: tex11-znf414 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005187 ! TEX11_HUMAN relationship: has_participant CCO:B0058231 ! ZN414_HUMAN [Term] id: CCO:I0015110 name: birc4-dlc2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0062812 ! DYL2_HUMAN [Term] id: CCO:I0015111 name: khdrbs3-rbmx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753907 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005256 ! HNRPG_HUMAN relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN [Term] id: CCO:I0015112 name: mgc13057-prkar1a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753910 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0062813 ! YB056_HUMAN [Term] id: CCO:I0015113 name: gfap-pdlim1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753913 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005319 ! PDLI1_HUMAN relationship: has_participant CCO:B0062814 ! GFAP_HUMAN [Term] id: CCO:I0015114 name: flj36046-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753916 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062815 ! CC116_HUMAN [Term] id: CCO:I0015115 name: golga2-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN relationship: has_participant CCO:B0055041 ! ZN250_HUMAN [Term] id: CCO:I0015116 name: bnip3l-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753931 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:I0015117 name: gabrd-ubqln1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005181 ! UBQL1_HUMAN relationship: has_participant CCO:B0022931 ! GBRD_HUMAN [Term] id: CCO:I0015118 name: krt15-loc112869 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753961 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0058208 ! SGF29_HUMAN [Term] id: CCO:I0015119 name: myoz-pnkp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753964 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005306 ! MYOZ1_HUMAN relationship: has_participant CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:I0015120 name: ewsr1-nsun4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-753997 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062816 ! NSUN4_HUMAN [Term] id: CCO:I0015121 name: drr1-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754000 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015122 name: kiaa0514-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005311 ! GRIN2_HUMAN [Term] id: CCO:I0015123 name: actg1-cfl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754012 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015628 ! ACTG_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0015124 name: appbp2-eid3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032335 ! EID3_HUMAN relationship: has_participant CCO:B0062805 ! APBP2_HUMAN [Term] id: CCO:I0015125 name: hgs-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005210 ! USBP1_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0015126 name: efemp2-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754042 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0005297 ! ZN263_HUMAN [Term] id: CCO:I0015127 name: dut-spata2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055266 ! DUT_HUMAN relationship: has_participant CCO:B0062808 ! SPAT2_HUMAN [Term] id: CCO:I0015128 name: c16orf48-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062810 ! CP048_HUMAN [Term] id: CCO:I0015129 name: ewsr1-hrb2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062817 ! KRR1_HUMAN [Term] id: CCO:I0015130 name: spg21-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015131 name: dtx2-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0015132 name: krt15-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0005207 ! K1C15_HUMAN [Term] id: CCO:I0015133 name: trappc2-zbed1x physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754111 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005231 ! ZBED1_HUMAN relationship: has_participant CCO:B0054354 ! TPPC2_HUMAN [Term] id: CCO:I0015134 name: plscr1-sf1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754123 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:I0015135 name: cdc42ep4-wdr6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058708 ! BORG4_HUMAN relationship: has_participant CCO:B0062818 ! Q6PKC6_HUMAN [Term] id: CCO:I0015136 name: rab33a-rabac1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055956 ! RB33A_HUMAN relationship: has_participant CCO:B0062819 ! PRAF1_HUMAN [Term] id: CCO:I0015137 name: myst2-q96br9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0062820 ! Q96BR9_HUMAN [Term] id: CCO:I0015138 name: ldb1-ssbp4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754153 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057244 ! LDB1_HUMAN relationship: has_participant CCO:B0062821 ! SSBP4_HUMAN [Term] id: CCO:I0015139 name: lrsam1-tsg101 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754159 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0006335 ! LRSM1_HUMAN [Term] id: CCO:I0015140 name: mgc33948-sumo1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754177 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN relationship: has_participant CCO:B0062822 ! CK065_HUMAN [Term] id: CCO:I0015141 name: c6orf4-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0054515 ! CIKS_HUMAN [Term] id: CCO:I0015142 name: dtx2-hpcal4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754192 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057257 ! DTX2_HUMAN relationship: has_participant CCO:B0062823 ! HPCL4_HUMAN [Term] id: CCO:I0015143 name: ap2m1-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062824 ! AP2M1_HUMAN [Term] id: CCO:I0015144 name: nif3l1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754204 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015145 name: hkr3-q96br9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054968 ! ZBT48_HUMAN relationship: has_participant CCO:B0062820 ! Q96BR9_HUMAN [Term] id: CCO:I0015146 name: gorasp2-mif physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005241 ! GORS2_HUMAN relationship: has_participant CCO:B0055021 ! MIF_HUMAN [Term] id: CCO:I0015147 name: ewsr1-wwp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0058653 ! WWP1_HUMAN [Term] id: CCO:I0015148 name: med4-tnfaip8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0054753 ! TFIP8_HUMAN [Term] id: CCO:I0015149 name: drap1-pole3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0015150 name: eif3s12-eif3s6ip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026274 ! EIF3K_HUMAN relationship: has_participant CCO:B0026279 ! IF3EI_HUMAN [Term] id: CCO:I0015151 name: ldoc1-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015152 name: sdcbp2-tifa physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058662 ! SDCB2_HUMAN relationship: has_participant CCO:B0062825 ! TIFA_HUMAN [Term] id: CCO:I0015153 name: atf4-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005172 ! Q96AQ3_HUMAN relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN [Term] id: CCO:I0015154 name: ash2l-loc84661 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0062826 ! DPY30_HUMAN [Term] id: CCO:I0015155 name: ehmt2-hgs physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754303 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0051938 ! EHMT2_HUMAN [Term] id: CCO:I0015156 name: nif3l1-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015157 name: mgc2749-tceb3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005184 ! CS050_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015158 name: c20orf75-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062827 ! LRRN4_HUMAN [Term] id: CCO:I0015159 name: sox30-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0020266 ! SOX30_HUMAN [Term] id: CCO:I0015160 name: jm11-pscd2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058410 ! CYH2_HUMAN relationship: has_participant CCO:B0062828 ! CC120_HUMAN [Term] id: CCO:I0015161 name: ewsr1-flj22318 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754357 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0037027 ! RMD5B_HUMAN [Term] id: CCO:I0015162 name: baiap2-nckipsd physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059278 ! BAIP2_HUMAN relationship: has_participant CCO:B0062829 ! Q6GU34_HUMAN [Term] id: CCO:I0015163 name: lpxn-phf21a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754372 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017845 ! LPXN_HUMAN relationship: has_participant CCO:B0058162 ! PF21A_HUMAN [Term] id: CCO:I0015164 name: rab11a-rab3il1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754375 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038438 ! RB11A_HUMAN relationship: has_participant CCO:B0062830 ! R3GEF_HUMAN [Term] id: CCO:I0015165 name: xab1-zbed1x physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005231 ! ZBED1_HUMAN relationship: has_participant CCO:B0058813 ! GPN1_HUMAN [Term] id: CCO:I0015166 name: nol3-ptpns1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054591 ! NOL3_HUMAN relationship: has_participant CCO:B0062831 ! SHPS1_HUMAN [Term] id: CCO:I0015167 name: fksg26-sat physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006107 ! SAT1_HUMAN relationship: has_participant CCO:B0058475 ! TCF25_HUMAN [Term] id: CCO:I0015168 name: aqp1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0034159 ! AQP1_HUMAN [Term] id: CCO:I0015169 name: mapk14-zfp36l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0026498 ! TISB_HUMAN [Term] id: CCO:I0015170 name: c6orf55-kctd13 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005259 ! VTA1_HUMAN relationship: has_participant CCO:B0058049 ! KCD13_HUMAN [Term] id: CCO:I0015171 name: lnx-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005305 ! LNX1_HUMAN [Term] id: CCO:I0015172 name: drr1-tada2l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005318 ! Q9BVJ0_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015173 name: kiaa1279-znf670 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043863 ! KBP_HUMAN relationship: has_participant CCO:B0058504 ! ZN670_HUMAN [Term] id: CCO:I0015174 name: hoxb9-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0036838 ! HXB9_HUMAN [Term] id: CCO:I0015175 name: mdfi-nr1h2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0055525 ! NR1H2_HUMAN [Term] id: CCO:I0015176 name: ewsr1-slc1a1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062832 ! EAA3_HUMAN [Term] id: CCO:I0015177 name: ewsr1-rasl11b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0058470 ! RSLBB_HUMAN [Term] id: CCO:I0015178 name: ppfia1-ppp2r5d physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754498 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN relationship: has_participant CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:I0015179 name: prdx1-q96gl3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055775 ! PRDX1_HUMAN relationship: has_participant CCO:B0058218 ! Q96GL3_HUMAN [Term] id: CCO:I0015180 name: ilf3-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0062833 ! Q9NXX0_HUMAN [Term] id: CCO:I0015181 name: c9orf100-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0057467 ! CI100_HUMAN [Term] id: CCO:I0015182 name: aff4-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005236 ! Q8TAX5_HUMAN [Term] id: CCO:I0015183 name: ing5-mgc2749 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754522 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005184 ! CS050_HUMAN relationship: has_participant CCO:B0005284 ! ING5_HUMAN [Term] id: CCO:I0015184 name: dppa4-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0062834 ! DPPA4_HUMAN [Term] id: CCO:I0015185 name: hif1a-ssx4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0054532 ! SSX4_HUMAN [Term] id: CCO:I0015186 name: begain-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754543 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN relationship: has_participant CCO:B0055041 ! ZN250_HUMAN [Term] id: CCO:I0015187 name: grap2-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN [Term] id: CCO:I0015188 name: als2cr8-lmo3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057425 ! AL2S8_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015189 name: dffa-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0054307 ! DFFA_HUMAN [Term] id: CCO:I0015190 name: drr1-vim physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015191 name: mdfi-znf679 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0057393 ! ZN679_HUMAN [Term] id: CCO:I0015192 name: traf2-znf646 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005230 ! Q8IVD8_HUMAN [Term] id: CCO:I0015193 name: asb9-hif1an physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058199 ! ASB9_HUMAN relationship: has_participant CCO:B0058941 ! HIF1N_HUMAN [Term] id: CCO:I0015194 name: hnrpk-matr3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:I0015195 name: mdfi-slc35a2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754621 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062835 ! Q8IV21_HUMAN [Term] id: CCO:I0015196 name: cry1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754639 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0056142 ! CRY1_HUMAN [Term] id: CCO:I0015197 name: ablim1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754645 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:I0015198 name: plekhf2-rtn4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:I0015199 name: ewsr1-wdr37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062836 ! Q8WVG2_HUMAN [Term] id: CCO:I0015200 name: gage5-gmcl1l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033870 ! GAGE5_HUMAN relationship: has_participant CCO:B0057588 ! GMCLL_HUMAN [Term] id: CCO:I0015201 name: sf1-trim23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754660 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055308 ! ARD1_HUMAN relationship: has_participant CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:I0015202 name: cpsf5-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062837 ! CPSF5_HUMAN [Term] id: CCO:I0015203 name: mdfi-zbtb25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0055169 ! ZBT25_HUMAN [Term] id: CCO:I0015204 name: khdrbs3-lnx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN relationship: has_participant CCO:B0005305 ! LNX1_HUMAN [Term] id: CCO:I0015205 name: krtap4_12-mgc13138 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005276 ! ZN764_HUMAN relationship: has_participant CCO:B0005293 ! KR412_HUMAN [Term] id: CCO:I0015206 name: flj20850-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062838 ! CS060_HUMAN [Term] id: CCO:I0015207 name: sh3gl1-sh3gl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN [Term] id: CCO:I0015208 name: kiaa1279-rgr physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043863 ! KBP_HUMAN relationship: has_participant CCO:B0055386 ! RGR_HUMAN [Term] id: CCO:I0015209 name: q96fa9-scand1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019498 ! SCND1_HUMAN relationship: has_participant CCO:B0029281 ! Q96FA9_HUMAN [Term] id: CCO:I0015210 name: arfip2-dtnbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0015211 name: abi3-nifie14 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038093 ! ABI3_HUMAN relationship: has_participant CCO:B0062839 ! TM147_HUMAN [Term] id: CCO:I0015212 name: rabac1-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058995 ! SPG21_HUMAN relationship: has_participant CCO:B0062819 ! PRAF1_HUMAN [Term] id: CCO:I0015213 name: cdc42-cdc42ep1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754756 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:I0015214 name: tceb3b-znf297b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754759 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054468 ! ZBT43_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015215 name: cbx2-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0056013 ! CBX2_HUMAN [Term] id: CCO:I0015216 name: pepp2-serf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0043420 ! SERF2_HUMAN [Term] id: CCO:I0015217 name: c7orf34-hkr3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754801 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054968 ! ZBT48_HUMAN relationship: has_participant CCO:B0062840 ! CG034_HUMAN [Term] id: CCO:I0015218 name: ddx17-sf1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056089 ! SF01_HUMAN relationship: has_participant CCO:B0062841 ! DDX17_HUMAN [Term] id: CCO:I0015219 name: tex11-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005187 ! TEX11_HUMAN [Term] id: CCO:I0015220 name: c12orf12-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062842 ! CL012_HUMAN [Term] id: CCO:I0015221 name: drr1-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005210 ! USBP1_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015222 name: c16orf48-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062810 ! CP048_HUMAN [Term] id: CCO:I0015223 name: cry1-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0056142 ! CRY1_HUMAN [Term] id: CCO:I0015224 name: kiaa0514-ywhae physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005311 ! GRIN2_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN [Term] id: CCO:I0015225 name: pepp2-rbm9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754879 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0015226 name: sf1-wwp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056089 ! SF01_HUMAN relationship: has_participant CCO:B0062807 ! WWP2_HUMAN [Term] id: CCO:I0015227 name: exoc8-hgs physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754885 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005255 ! EXOC8_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0015228 name: gnmt-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062843 ! GNMT_HUMAN [Term] id: CCO:I0015229 name: aqp5-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062844 ! AQP5_HUMAN [Term] id: CCO:I0015230 name: c11orf16-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0019601 ! CK016_HUMAN [Term] id: CCO:I0015231 name: pom121-trim23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055308 ! ARD1_HUMAN relationship: has_participant CCO:B0061984 ! P121A_HUMAN [Term] id: CCO:I0015232 name: appbp2-creb3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754921 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0062805 ! APBP2_HUMAN [Term] id: CCO:I0015233 name: ap2m1-med4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0062824 ! AP2M1_HUMAN [Term] id: CCO:I0015234 name: smarcd1-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005210 ! USBP1_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN [Term] id: CCO:I0015235 name: ctbp2-rai2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN relationship: has_participant CCO:B0062845 ! RAI2_HUMAN [Term] id: CCO:I0015236 name: dazap2-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754969 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005214 ! ZN581_HUMAN [Term] id: CCO:I0015237 name: tsc22d4-znf580 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754987 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005228 ! ZN580_HUMAN [Term] id: CCO:I0015238 name: krtap4_12-top3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754990 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0054815 ! TOP3B_HUMAN [Term] id: CCO:I0015239 name: lmo3-q96br9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-754999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057890 ! LMO3_HUMAN relationship: has_participant CCO:B0062820 ! Q96BR9_HUMAN [Term] id: CCO:I0015240 name: ewsr1-rnf183 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062846 ! RN183_HUMAN [Term] id: CCO:I0015241 name: sat-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0015242 name: dhrs1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755020 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062847 ! DHRS1_HUMAN [Term] id: CCO:I0015243 name: ctps2-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755023 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0049297 ! PYRG2_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015244 name: ap2m1-znfn1a1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755029 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005213 ! IKZF1_HUMAN relationship: has_participant CCO:B0062824 ! AP2M1_HUMAN [Term] id: CCO:I0015245 name: dtnb-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0030221 ! Q96AW0_HUMAN [Term] id: CCO:I0015246 name: rhpn1-trim37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755044 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0057918 ! RHPN1_HUMAN [Term] id: CCO:I0015247 name: ps1d-sdcbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755053 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058662 ! SDCB2_HUMAN relationship: has_participant CCO:B0062848 ! NO40_HUMAN [Term] id: CCO:I0015248 name: mbip-rap1gds1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755071 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0029859 ! Q9BUX6_HUMAN [Term] id: CCO:I0015249 name: mdfi-serf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755074 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0043420 ! SERF2_HUMAN [Term] id: CCO:I0015250 name: eif4el3-eif4enif1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755083 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006012 ! 4ET_HUMAN relationship: has_participant CCO:B0054567 ! IF4E2_HUMAN [Term] id: CCO:I0015251 name: rad23a-sqstm1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN relationship: has_participant CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:I0015252 name: c9orf100-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0057467 ! CI100_HUMAN [Term] id: CCO:I0015253 name: ldoc1-nrip1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:I0015254 name: gga2-trim23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005200 ! GGA2_HUMAN relationship: has_participant CCO:B0055308 ! ARD1_HUMAN [Term] id: CCO:I0015255 name: lmo3-znf297b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054468 ! ZBT43_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015256 name: snap25-stx11-1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755143 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005220 ! STX11_HUMAN relationship: has_participant CCO:B0055598 ! SNP25_HUMAN [Term] id: CCO:I0015257 name: qars-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755161 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062850 ! Q96AW5_HUMAN [Term] id: CCO:I0015258 name: kiaa0470l-lmo3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057890 ! LMO3_HUMAN relationship: has_participant CCO:B0062851 ! C170L_HUMAN [Term] id: CCO:I0015259 name: kiaa1849-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0058240 ! RADIL_HUMAN [Term] id: CCO:I0015260 name: ewsr1-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755191 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0015261 name: aatf-dazap2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0015262 name: mdfi-znf559 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755209 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0058485 ! ZN559_HUMAN [Term] id: CCO:I0015263 name: eif2ak4-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755212 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0059059 ! E2AK4_HUMAN [Term] id: CCO:I0015264 name: ewsr1-kel physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755227 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062852 ! KELL_HUMAN [Term] id: CCO:I0015265 name: dkfzp434h1428-eif3s6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN relationship: has_participant CCO:B0058796 ! GPBL1_HUMAN [Term] id: CCO:I0015266 name: krt15-tsg101 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755239 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0015267 name: gnl3l-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755245 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0062853 ! GNL3L_HUMAN [Term] id: CCO:I0015268 name: aasdhppt-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755251 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062778 ! ADPPT_HUMAN [Term] id: CCO:I0015269 name: chic2-hoxa1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020052 ! CHIC2_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0015270 name: hook1-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755272 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005594 ! HOOK1_HUMAN relationship: has_participant CCO:B0055041 ! ZN250_HUMAN [Term] id: CCO:I0015271 name: ewsr1-myoz2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005250 ! MYOZ2_HUMAN [Term] id: CCO:I0015272 name: dach1-nagk physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755281 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0062854 ! NAGK_HUMAN [Term] id: CCO:I0015273 name: c1orf117-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755290 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005290 ! F131C_HUMAN [Term] id: CCO:I0015274 name: dvl2-tifa physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062825 ! TIFA_HUMAN [Term] id: CCO:I0015275 name: mdfi-mfsd3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755305 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062855 ! MFSD3_HUMAN [Term] id: CCO:I0015276 name: ctbp2-tead3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755314 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN relationship: has_participant CCO:B0032261 ! TEAD3_HUMAN [Term] id: CCO:I0015277 name: rfx2-rfxdc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028084 ! Q8SNA2_HUMAN relationship: has_participant CCO:B0061983 ! RFX6_HUMAN [Term] id: CCO:I0015278 name: amotl2-mpp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005299 ! AMOL2_HUMAN relationship: has_participant CCO:B0019045 ! EM55_HUMAN [Term] id: CCO:I0015279 name: c6orf119-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0062856 ! F103A_HUMAN [Term] id: CCO:I0015280 name: asb9-ckb physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755338 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015997 ! KCRB_HUMAN relationship: has_participant CCO:B0058199 ! ASB9_HUMAN [Term] id: CCO:I0015281 name: hmg20a-magoh2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755353 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005296 ! HM20A_HUMAN relationship: has_participant CCO:B0062857 ! MGN2_HUMAN [Term] id: CCO:I0015282 name: pmm1-rab6a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037580 ! PMM1_HUMAN relationship: has_participant CCO:B0055118 ! RAB6A_HUMAN [Term] id: CCO:I0015283 name: abi3-homer1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755365 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038093 ! ABI3_HUMAN relationship: has_participant CCO:B0057307 ! HOME1_HUMAN [Term] id: CCO:I0015284 name: znf165-znf446 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015285 name: ewsr1-hmga1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755377 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:I0015286 name: abi3-snap23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038093 ! ABI3_HUMAN relationship: has_participant CCO:B0062858 ! SNP23_HUMAN [Term] id: CCO:I0015287 name: hnrpk-mgc10433 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755383 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0062859 ! RBM42_HUMAN [Term] id: CCO:I0015288 name: ndp52-tcfl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0015289 name: thap7-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755407 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0058511 ! THAP7_HUMAN [Term] id: CCO:I0015290 name: hgs-nmi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0015291 name: fzd7-ubqln1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005181 ! UBQL1_HUMAN relationship: has_participant CCO:B0038856 ! FZD7_HUMAN [Term] id: CCO:I0015292 name: loc541468-loc55565 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054649 ! ZN821_HUMAN relationship: has_participant CCO:B0062781 ! CA190_HUMAN [Term] id: CCO:I0015293 name: rbpms-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755443 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005214 ! ZN581_HUMAN [Term] id: CCO:I0015294 name: fastk-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062860 ! Q9BWD7_HUMAN [Term] id: CCO:I0015295 name: eif4ebp3-eif4el3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755467 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054565 ! 4EBP3_HUMAN relationship: has_participant CCO:B0054567 ! IF4E2_HUMAN [Term] id: CCO:I0015296 name: nif3l1-tifa physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062825 ! TIFA_HUMAN [Term] id: CCO:I0015297 name: gabarapl1-sqstm1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0051353 ! GBRL1_HUMAN relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:I0015298 name: arrb1-gnmt physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055424 ! ARRB1_HUMAN relationship: has_participant CCO:B0062843 ! GNMT_HUMAN [Term] id: CCO:I0015299 name: dtx2-freq physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057257 ! DTX2_HUMAN relationship: has_participant CCO:B0062861 ! NCS1_HUMAN [Term] id: CCO:I0015300 name: ap1m1-mtf1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056022 ! MTF1_HUMAN relationship: has_participant CCO:B0062862 ! AP1M1_HUMAN [Term] id: CCO:I0015301 name: ewsr1-nppb physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0055059 ! ANFB_HUMAN [Term] id: CCO:I0015302 name: tsc22d4-zmynd10 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0062863 ! ZMY10_HUMAN [Term] id: CCO:I0015303 name: c1orf165-ctnnbip1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN relationship: has_participant CCO:B0062795 ! CA165_HUMAN [Term] id: CCO:I0015304 name: gabpb2-lmo3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755563 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040683 ! GABP1_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015305 name: c1orf41-rabl4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058530 ! RAYL_HUMAN relationship: has_participant CCO:B0062864 ! HSB11_HUMAN [Term] id: CCO:I0015306 name: mbip-wdr5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755569 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0005615 ! WDR5_HUMAN [Term] id: CCO:I0015307 name: rfxdc1-ss18l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0061983 ! RFX6_HUMAN relationship: has_participant CCO:B0062865 ! S18L1_HUMAN [Term] id: CCO:I0015308 name: krtap4_12-znf426 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755593 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0058524 ! ZN426_HUMAN [Term] id: CCO:I0015309 name: hoxb6-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755602 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036826 ! HXB6_HUMAN relationship: has_participant CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:I0015310 name: begain-znf417 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN relationship: has_participant CCO:B0057893 ! ZN417_HUMAN [Term] id: CCO:I0015311 name: dtx2-rfxdc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057257 ! DTX2_HUMAN relationship: has_participant CCO:B0061983 ! RFX6_HUMAN [Term] id: CCO:I0015312 name: ewsr1-herpud1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0026851 ! HERP1_HUMAN [Term] id: CCO:I0015313 name: nif3l1-rpia physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0024182 ! RPIA_HUMAN [Term] id: CCO:I0015314 name: dazap2-tollip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755629 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN [Term] id: CCO:I0015315 name: ewsr1-prv1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755635 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062866 ! CD177_HUMAN [Term] id: CCO:I0015316 name: mdfi-znf607 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062867 ! ZN607_HUMAN [Term] id: CCO:I0015317 name: bag3-q8wu02 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755647 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005304 ! Q8WU02_HUMAN relationship: has_participant CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:I0015318 name: dgcr6l-mbip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0062868 ! DGC6L_HUMAN [Term] id: CCO:I0015319 name: mdfi-thap7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0058511 ! THAP7_HUMAN [Term] id: CCO:I0015320 name: kctd17-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0043424 ! KCD17_HUMAN [Term] id: CCO:I0015321 name: mdfi-otx1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0055254 ! OTX1_HUMAN [Term] id: CCO:I0015322 name: traf2-znf297b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755680 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0054468 ! ZBT43_HUMAN [Term] id: CCO:I0015323 name: creb3-emd physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755689 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:I0015324 name: dkfzp434h142-plekhf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755692 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0058796 ! GPBL1_HUMAN [Term] id: CCO:I0015325 name: ewsr1-rpl31 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0015391 ! RL31_HUMAN [Term] id: CCO:I0015326 name: ndp52-znf451 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005308 ! ZN451_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0015327 name: pcqap-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:I0015328 name: ipo13-pax6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0062870 ! IPO13_HUMAN [Term] id: CCO:I0015329 name: trim37-znf655 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0058476 ! Q9BQ85_HUMAN [Term] id: CCO:I0015330 name: krtap4_12-pfkl physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0034104 ! K6PL_HUMAN [Term] id: CCO:I0015331 name: ewsr1-tcfl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755743 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN [Term] id: CCO:I0015332 name: actl6a-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN [Term] id: CCO:I0015333 name: spry2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062871 ! SPY2_HUMAN [Term] id: CCO:I0015334 name: nono-plekhf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755764 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0005234 ! NONO_HUMAN [Term] id: CCO:I0015335 name: c6orf4-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755779 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0054515 ! CIKS_HUMAN [Term] id: CCO:I0015336 name: phc1-sfmbt1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005264 ! PHC1_HUMAN relationship: has_participant CCO:B0059142 ! SMBT1_HUMAN [Term] id: CCO:I0015337 name: gorasp2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005241 ! GORS2_HUMAN [Term] id: CCO:I0015338 name: bcl2l13-gabarapl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026744 ! B2L13_HUMAN relationship: has_participant CCO:B0051349 ! GBRL2_HUMAN [Term] id: CCO:I0015339 name: asb13-hif1an physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058029 ! ASB13_HUMAN relationship: has_participant CCO:B0058941 ! HIF1N_HUMAN [Term] id: CCO:I0015340 name: ilf3-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062833 ! Q9NXX0_HUMAN [Term] id: CCO:I0015341 name: imp3-lpxn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017845 ! LPXN_HUMAN relationship: has_participant CCO:B0062872 ! IMP3_HUMAN [Term] id: CCO:I0015342 name: psf2-sld5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017505 ! PSF2_HUMAN relationship: has_participant CCO:B0058497 ! SLD5_HUMAN [Term] id: CCO:I0015343 name: ihpk2-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0059140 ! IP6K2_HUMAN [Term] id: CCO:I0015344 name: ewsr1-rad23a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:I0015345 name: traf2-traf6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0015346 name: aatf-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN [Term] id: CCO:I0015347 name: znf263-znf446 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN relationship: has_participant CCO:B0005297 ! ZN263_HUMAN [Term] id: CCO:I0015348 name: rara-rxrg physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024853 ! RARA_HUMAN relationship: has_participant CCO:B0024881 ! RXRG_HUMAN [Term] id: CCO:I0015349 name: lims1-lpxn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017845 ! LPXN_HUMAN relationship: has_participant CCO:B0062873 ! LIMS1_HUMAN [Term] id: CCO:I0015350 name: traf2-trim31 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062874 ! TRI31_HUMAN [Term] id: CCO:I0015351 name: dvl2-tceb3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015352 name: krtap4_12-znf439 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0057577 ! ZN439_HUMAN [Term] id: CCO:I0015353 name: arhgap1-rhoc physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020594 ! RHOC_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN [Term] id: CCO:I0015354 name: ctbp2-nol4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN relationship: has_participant CCO:B0062875 ! NOL4_HUMAN [Term] id: CCO:I0015355 name: elf5-sirt6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057492 ! SIRT6_HUMAN relationship: has_participant CCO:B0059208 ! ELF5_HUMAN [Term] id: CCO:I0015356 name: ilk-parva physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755965 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055907 ! ILK_HUMAN relationship: has_participant CCO:B0062876 ! PARVA_HUMAN [Term] id: CCO:I0015357 name: snf8-vps25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-755998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018982 ! SNF8_HUMAN relationship: has_participant CCO:B0058490 ! VPS25_HUMAN [Term] id: CCO:I0015358 name: rps14-taf9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:I0015359 name: ldoc1-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0055041 ! ZN250_HUMAN [Term] id: CCO:I0015360 name: ewsr1-magea11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0015361 name: q96bk2-wwtr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032264 ! Q96BK2_HUMAN relationship: has_participant CCO:B0058638 ! WWTR1_HUMAN [Term] id: CCO:I0015362 name: cdc42ep3-cdc42ep3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059193 ! BORG2_HUMAN [Term] id: CCO:I0015363 name: c1orf117-grn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005290 ! F131C_HUMAN relationship: has_participant CCO:B0005961 ! GRN_HUMAN [Term] id: CCO:I0015364 name: ldoc1-znfn1a5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0062877 ! Q8TBE5_HUMAN [Term] id: CCO:I0015365 name: ap2b1-ldlrap1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756082 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005197 ! AP2B1_HUMAN relationship: has_participant CCO:B0056547 ! ARH_HUMAN [Term] id: CCO:I0015366 name: abi2-nck2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038095 ! ABI2_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:I0015367 name: rtn3-rtn4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756091 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041728 ! RTN3_HUMAN relationship: has_participant CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:I0015368 name: cfdp1-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0059107 ! CFDP1_HUMAN [Term] id: CCO:I0015369 name: abi3-krt15 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0038093 ! ABI3_HUMAN [Term] id: CCO:I0015370 name: hook2-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756127 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055041 ! ZN250_HUMAN relationship: has_participant CCO:B0062809 ! HOOK2_HUMAN [Term] id: CCO:I0015371 name: c8orf32-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005179 ! CH032_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0015372 name: ribc2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005240 ! RIBC2_HUMAN [Term] id: CCO:I0015373 name: kiaa0470l-runx1t1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055769 ! MTG8_HUMAN relationship: has_participant CCO:B0062851 ! C170L_HUMAN [Term] id: CCO:I0015374 name: hoxa9-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0055236 ! HXA9_HUMAN [Term] id: CCO:I0015375 name: cxadr-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756181 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062878 ! CXAR_HUMAN [Term] id: CCO:I0015376 name: ctbp2-fts physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756202 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN relationship: has_participant CCO:B0026276 ! AKTIP_HUMAN [Term] id: CCO:I0015377 name: abi3-eif3s3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038093 ! ABI3_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0015378 name: mtmr9-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026696 ! MTMR9_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015379 name: catsper1-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756220 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0062879 ! CTSR1_HUMAN [Term] id: CCO:I0015380 name: dhps-eif5a2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756238 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036577 ! IF5A2_HUMAN relationship: has_participant CCO:B0055423 ! DHYS_HUMAN [Term] id: CCO:I0015381 name: ewsr1-znf165 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015382 name: thap1-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0062880 ! THAP1_HUMAN [Term] id: CCO:I0015383 name: lnx-pcbd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005305 ! LNX1_HUMAN relationship: has_participant CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:I0015384 name: ewsr1-ssbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0055656 ! SSBP2_HUMAN [Term] id: CCO:I0015385 name: c18orf10-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756280 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062881 ! TPGS2_HUMAN [Term] id: CCO:I0015386 name: loc286075-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756283 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0058175 ! ZN707_HUMAN [Term] id: CCO:I0015387 name: ewsr1-rab37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0058157 ! RAB37_HUMAN [Term] id: CCO:I0015388 name: nck2-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:I0015389 name: cbx5-mgc3121 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756307 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0062882 ! PRR14_HUMAN [Term] id: CCO:I0015390 name: crx-loc130951 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054456 ! CRX_HUMAN relationship: has_participant CCO:B0062883 ! CB065_HUMAN [Term] id: CCO:I0015391 name: nrip1-tex11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005187 ! TEX11_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:I0015392 name: hgs-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756325 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0015393 name: krtap4_12-znf417 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0057893 ! ZN417_HUMAN [Term] id: CCO:I0015394 name: s100a1-s100a1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0015395 name: nol3-vasp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054591 ! NOL3_HUMAN relationship: has_participant CCO:B0062884 ! VASP_HUMAN [Term] id: CCO:I0015396 name: c8orf32-hprt1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005179 ! CH032_HUMAN relationship: has_participant CCO:B0036957 ! HPRT_HUMAN [Term] id: CCO:I0015397 name: dhps-rpl9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756367 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055423 ! DHYS_HUMAN relationship: has_participant CCO:B0062885 ! RL9_HUMAN [Term] id: CCO:I0015398 name: mdfi-znf439 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756373 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0057577 ! ZN439_HUMAN [Term] id: CCO:I0015399 name: krt15-krt6a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756376 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0005821 ! K2C6A_HUMAN [Term] id: CCO:I0015400 name: sall2-zimp7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756391 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005218 ! ZMIZ2_HUMAN relationship: has_participant CCO:B0062886 ! Q8N656_HUMAN [Term] id: CCO:I0015401 name: ehmt2-klf6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0051938 ! EHMT2_HUMAN relationship: has_participant CCO:B0058431 ! KLF6_HUMAN [Term] id: CCO:I0015402 name: mgc2749-zbtb25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005184 ! CS050_HUMAN relationship: has_participant CCO:B0055169 ! ZBT25_HUMAN [Term] id: CCO:I0015403 name: pitx1-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0055638 ! PITX1_HUMAN [Term] id: CCO:I0015404 name: hoxb9-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756421 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0036838 ! HXB9_HUMAN [Term] id: CCO:I0015405 name: cetp-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756427 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062887 ! CETP_HUMAN [Term] id: CCO:I0015406 name: stmn2-tex11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005187 ! TEX11_HUMAN relationship: has_participant CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:I0015407 name: pbxip1-tsnax physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058154 ! PBIP1_HUMAN relationship: has_participant CCO:B0062792 ! TSNAX_HUMAN [Term] id: CCO:I0015408 name: nme3-sgta physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005316 ! NDK3_HUMAN relationship: has_participant CCO:B0006084 ! SGTA_HUMAN [Term] id: CCO:I0015409 name: ewsr1-ndufv1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062888 ! NDUV1_HUMAN [Term] id: CCO:I0015410 name: magea11-prdx3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0055216 ! PRDX3_HUMAN [Term] id: CCO:I0015411 name: dvl2-rnps1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062889 ! RNPS1_HUMAN [Term] id: CCO:I0015412 name: eif4el3-krt20 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023749 ! K1C20_HUMAN relationship: has_participant CCO:B0054567 ! IF4E2_HUMAN [Term] id: CCO:I0015413 name: ablim1-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:I0015414 name: lmo3-mgc2749 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005184 ! CS050_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015415 name: fbxw5-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0043433 ! FBXW5_HUMAN [Term] id: CCO:I0015416 name: dvl2-flj12529 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:I0015417 name: mdfi-rfx2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756511 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0028084 ! Q8SNA2_HUMAN [Term] id: CCO:I0015418 name: znf24-znf446 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0015419 name: ldb1-lmo3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057244 ! LDB1_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015420 name: dazap2-rbm9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756541 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0015421 name: jm11-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062828 ! CC120_HUMAN [Term] id: CCO:I0015422 name: col4a3bp-csnk1g2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020420 ! KC1G2_HUMAN relationship: has_participant CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:I0015423 name: nif3l1-trim21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756571 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062892 ! RO52_HUMAN [Term] id: CCO:I0015424 name: ppfia1-tnnt1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031630 ! LIPA1_HUMAN relationship: has_participant CCO:B0043421 ! TNNT1_HUMAN [Term] id: CCO:I0015425 name: meox2-samm50 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756583 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005623 ! MEOX2_HUMAN relationship: has_participant CCO:B0062893 ! SAM50_HUMAN [Term] id: CCO:I0015426 name: krt17-krt6a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756586 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005821 ! K2C6A_HUMAN relationship: has_participant CCO:B0005844 ! K1C17_HUMAN [Term] id: CCO:I0015427 name: dlc2-homer3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756589 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058915 ! HOME3_HUMAN relationship: has_participant CCO:B0062812 ! DYL2_HUMAN [Term] id: CCO:I0015428 name: chmp2b-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756604 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062894 ! CHM2B_HUMAN [Term] id: CCO:I0015429 name: bles03-wbscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056040 ! IF4H_HUMAN relationship: has_participant CCO:B0062895 ! CK068_HUMAN [Term] id: CCO:I0015430 name: c14orf32-pdcd6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756613 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041276 ! MISSL_HUMAN relationship: has_participant CCO:B0054618 ! PDCD6_HUMAN [Term] id: CCO:I0015431 name: mmrp19-vps25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0042018 ! APIP_HUMAN relationship: has_participant CCO:B0058490 ! VPS25_HUMAN [Term] id: CCO:I0015432 name: appbp2-wnt5b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058666 ! WNT5B_HUMAN relationship: has_participant CCO:B0062805 ! APBP2_HUMAN [Term] id: CCO:I0015433 name: rara-rxrb physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756652 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024853 ! RARA_HUMAN relationship: has_participant CCO:B0024878 ! RXRB_HUMAN [Term] id: CCO:I0015434 name: sertad3-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756673 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005210 ! USBP1_HUMAN relationship: has_participant CCO:B0059180 ! SRTD3_HUMAN [Term] id: CCO:I0015435 name: c8orf32-cbfa2t2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005179 ! CH032_HUMAN relationship: has_participant CCO:B0054482 ! MTG8R_HUMAN [Term] id: CCO:I0015436 name: ndp52-poli physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026268 ! CACO2_HUMAN relationship: has_participant CCO:B0059249 ! POLI_HUMAN [Term] id: CCO:I0015437 name: rcl-rcl physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756733 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054497 ! RCL_HUMAN [Term] id: CCO:I0015438 name: dlc2-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062812 ! DYL2_HUMAN [Term] id: CCO:I0015439 name: dvl2-snf8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0018982 ! SNF8_HUMAN [Term] id: CCO:I0015440 name: ipo11-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756769 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0024299 ! IPO11_HUMAN [Term] id: CCO:I0015441 name: kctd13-zmynd19 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756772 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058049 ! KCD13_HUMAN relationship: has_participant CCO:B0062896 ! ZMY19_HUMAN [Term] id: CCO:I0015442 name: smad4-smad9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756775 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0054414 ! SMAD9_HUMAN [Term] id: CCO:I0015443 name: eef1d-eef1g-1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0021083 ! Q96I38_HUMAN [Term] id: CCO:I0015444 name: pnkp-trim37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:I0015445 name: plcd4-trim39 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043417 ! TRI39_HUMAN relationship: has_participant CCO:B0058489 ! PLCD4_HUMAN [Term] id: CCO:I0015446 name: ddx39-hcc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055658 ! HCC1_HUMAN relationship: has_participant CCO:B0062897 ! DDX39_HUMAN [Term] id: CCO:I0015447 name: c6orf55-mbip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005259 ! VTA1_HUMAN relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN [Term] id: CCO:I0015448 name: scand1-znf434 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756829 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019498 ! SCND1_HUMAN relationship: has_participant CCO:B0062898 ! Q9BU74_HUMAN [Term] id: CCO:I0015449 name: kctd13-lnx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756835 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005305 ! LNX1_HUMAN relationship: has_participant CCO:B0058049 ! KCD13_HUMAN [Term] id: CCO:I0015450 name: gcsh-nmi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0062899 ! GCSH_HUMAN [Term] id: CCO:I0015451 name: rbpms-sf1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0056089 ! SF01_HUMAN [Term] id: CCO:I0015452 name: krtap4_12-thap7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756889 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0058511 ! THAP7_HUMAN [Term] id: CCO:I0015453 name: pde9a-phyhipl physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756892 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054693 ! PDE9A_HUMAN relationship: has_participant CCO:B0062900 ! PHIPL_HUMAN [Term] id: CCO:I0015454 name: mdfi-tinagl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0027449 ! TINAL_HUMAN [Term] id: CCO:I0015455 name: morf4l1-mrfap1l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005917 ! MO4L1_HUMAN relationship: has_participant CCO:B0062901 ! MR1L1_HUMAN [Term] id: CCO:I0015456 name: mdfi-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756913 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015457 name: hnrpk-npdc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756931 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0062902 ! NPDC1_HUMAN [Term] id: CCO:I0015458 name: hoxa1-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756955 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0015459 name: znf232-znf446 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756964 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN relationship: has_participant CCO:B0059257 ! ZN232_HUMAN [Term] id: CCO:I0015460 name: dtx2-ube2d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019459 ! UB2D4_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0015461 name: spg21-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756979 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005297 ! ZN263_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015462 name: mizf-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-756985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0058478 ! MIZF_HUMAN [Term] id: CCO:I0015463 name: drap1-pik3r3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757012 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026605 ! Q8N381_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0015464 name: traf2-usp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757021 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062903 ! UBP2_HUMAN [Term] id: CCO:I0015465 name: mdfi-spg7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757036 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0006236 ! SPG7_HUMAN [Term] id: CCO:I0015466 name: hnrpc-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757039 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005214 ! ZN581_HUMAN relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN [Term] id: CCO:I0015467 name: rap1gds1-znf451 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005308 ! ZN451_HUMAN relationship: has_participant CCO:B0029859 ! Q9BUX6_HUMAN [Term] id: CCO:I0015468 name: trim41-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005297 ! ZN263_HUMAN relationship: has_participant CCO:B0062904 ! TRI41_HUMAN [Term] id: CCO:I0015469 name: cep72-znf417 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057893 ! ZN417_HUMAN relationship: has_participant CCO:B0062905 ! CEP72_HUMAN [Term] id: CCO:I0015470 name: med28-ushbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005210 ! USBP1_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN [Term] id: CCO:I0015471 name: nif3l1-nol3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757087 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0054591 ! NOL3_HUMAN [Term] id: CCO:I0015472 name: mdfi-znf136 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0055491 ! ZN136_HUMAN [Term] id: CCO:I0015473 name: lnx-trim23 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757111 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005305 ! LNX1_HUMAN relationship: has_participant CCO:B0055308 ! ARD1_HUMAN [Term] id: CCO:I0015474 name: prps1-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030301 ! PRPS1_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015475 name: ewsr1-q8n4d0 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0029706 ! Q8N4D0_HUMAN [Term] id: CCO:I0015476 name: dkfzp434h1428-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757159 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0058796 ! GPBL1_HUMAN [Term] id: CCO:I0015477 name: c13orf21-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757174 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062906 ! SERP2_HUMAN [Term] id: CCO:I0015478 name: mgc16186-nme5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757189 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055546 ! NDK5_HUMAN relationship: has_participant CCO:B0062907 ! DYDC2_HUMAN [Term] id: CCO:I0015479 name: hook2-ralbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056057 ! RBP1_HUMAN relationship: has_participant CCO:B0062809 ! HOOK2_HUMAN [Term] id: CCO:I0015480 name: dtx2-hpcal1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057257 ! DTX2_HUMAN relationship: has_participant CCO:B0062908 ! HPCL1_HUMAN [Term] id: CCO:I0015481 name: c15orf15-dnmt3l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037714 ! DNM3L_HUMAN relationship: has_participant CCO:B0062909 ! RLP24_HUMAN [Term] id: CCO:I0015482 name: fate1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062910 ! FATE1_HUMAN [Term] id: CCO:I0015483 name: pafah1b3-sdcbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN relationship: has_participant CCO:B0058662 ! SDCB2_HUMAN [Term] id: CCO:I0015484 name: q8n2x6-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062911 ! YE036_HUMAN [Term] id: CCO:I0015485 name: dvl2-snip1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN [Term] id: CCO:I0015486 name: bahd1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062793 ! BAHD1_HUMAN [Term] id: CCO:I0015487 name: dvl2-q96br9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062820 ! Q96BR9_HUMAN [Term] id: CCO:I0015488 name: csnk1e-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757243 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005272 ! KC1E_HUMAN [Term] id: CCO:I0015489 name: fksg26-magea11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0058475 ! TCF25_HUMAN [Term] id: CCO:I0015490 name: dvl2-prpf3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062912 ! PRPF3_HUMAN [Term] id: CCO:I0015491 name: eef1g-ilf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0055855 ! ILF2_HUMAN [Term] id: CCO:I0015492 name: ewsr1-gnpda1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062913 ! GNPI1_HUMAN [Term] id: CCO:I0015493 name: myst2-ndp52 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0015494 name: pdlim1-vim physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757279 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005319 ! PDLI1_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0015495 name: mbip-q96hl7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0062914 ! Q96HL7_HUMAN [Term] id: CCO:I0015496 name: ablim1-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:I0015497 name: begain-rfp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN relationship: has_participant CCO:B0005981 ! TRI27_HUMAN [Term] id: CCO:I0015498 name: znf167-znf434 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059030 ! ZN167_HUMAN relationship: has_participant CCO:B0062898 ! Q9BU74_HUMAN [Term] id: CCO:I0015499 name: cep70-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0062785 ! CEP70_HUMAN [Term] id: CCO:I0015500 name: cdc42ep1-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:I0015501 name: catsper1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062879 ! CTSR1_HUMAN [Term] id: CCO:I0015502 name: bnip3-tmem11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0055084 ! TMM11_HUMAN [Term] id: CCO:I0015503 name: batf-snapc5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005320 ! BATF_HUMAN relationship: has_participant CCO:B0054683 ! SNPC5_HUMAN [Term] id: CCO:I0015504 name: nck2-nckipsd physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0062829 ! Q6GU34_HUMAN [Term] id: CCO:I0015505 name: mbip-ppfia1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:I0015506 name: ctbp2-tgif physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006246 ! TGIF1_HUMAN relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN [Term] id: CCO:I0015507 name: grap2-ywhae physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN [Term] id: CCO:I0015508 name: dtx2-ncald physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057257 ! DTX2_HUMAN relationship: has_participant CCO:B0062915 ! NCALD_HUMAN [Term] id: CCO:I0015509 name: aggf1-pldn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005183 ! PLDN_HUMAN relationship: has_participant CCO:B0057450 ! AGGF1_HUMAN [Term] id: CCO:I0015510 name: lmo3-rfxdc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057890 ! LMO3_HUMAN relationship: has_participant CCO:B0061983 ! RFX6_HUMAN [Term] id: CCO:I0015511 name: begain-hgs physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757471 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN [Term] id: CCO:I0015512 name: magea11-pnkp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0058402 ! PNKP_HUMAN [Term] id: CCO:I0015513 name: l3mbtl2-stam2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058140 ! LMBL2_HUMAN relationship: has_participant CCO:B0062916 ! STAM2_HUMAN [Term] id: CCO:I0015514 name: napa-rtn4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0062917 ! SNAA_HUMAN [Term] id: CCO:I0015515 name: krtap4_12-meox2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0005623 ! MEOX2_HUMAN [Term] id: CCO:I0015516 name: bahd1-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062793 ! BAHD1_HUMAN [Term] id: CCO:I0015517 name: elavl3-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757519 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062918 ! ELAV3_HUMAN [Term] id: CCO:I0015518 name: cep70-znf426 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058524 ! ZN426_HUMAN relationship: has_participant CCO:B0062785 ! CEP70_HUMAN [Term] id: CCO:I0015519 name: bcon3-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757540 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0062919 ! NRBP_HUMAN [Term] id: CCO:I0015520 name: amotl2-gng11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757543 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005299 ! AMOL2_HUMAN relationship: has_participant CCO:B0055614 ! GBG11_HUMAN [Term] id: CCO:I0015521 name: scam_1-zbtb25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757555 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055169 ! ZBT25_HUMAN relationship: has_participant CCO:B0062920 ! Q96FY4_HUMAN [Term] id: CCO:I0015522 name: ldoc1-utp14a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0015523 name: lnx-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005305 ! LNX1_HUMAN [Term] id: CCO:I0015524 name: elavl4-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062921 ! Q8IYD4_HUMAN [Term] id: CCO:I0015525 name: ewsr1-lilra3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757600 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0057487 ! LIRA3_HUMAN [Term] id: CCO:I0015526 name: pepp2-pitx1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0055638 ! PITX1_HUMAN [Term] id: CCO:I0015527 name: cutc-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005203 ! Q96BX3_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015528 name: pdcd10-stk25 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022748 ! STK25_HUMAN relationship: has_participant CCO:B0062768 ! PDC10_HUMAN [Term] id: CCO:I0015529 name: mdfi-znf646 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005230 ! Q8IVD8_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0015530 name: mdfi-npdc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062902 ! NPDC1_HUMAN [Term] id: CCO:I0015531 name: hoxb6-krt15 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0036826 ! HXB6_HUMAN [Term] id: CCO:I0015532 name: c6orf165-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062922 ! CF165_HUMAN [Term] id: CCO:I0015533 name: ldb1-ssbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055656 ! SSBP2_HUMAN relationship: has_participant CCO:B0057244 ! LDB1_HUMAN [Term] id: CCO:I0015534 name: dazap2-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757693 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0015535 name: ndp52-pcgf1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026268 ! CACO2_HUMAN relationship: has_participant CCO:B0058507 ! PCGF1_HUMAN [Term] id: CCO:I0015536 name: bag3-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:I0015537 name: apg12l-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062923 ! ATG12_HUMAN [Term] id: CCO:I0015538 name: hgs-loc541468 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757732 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0062781 ! CA190_HUMAN [Term] id: CCO:I0015539 name: lnx-znf297b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005305 ! LNX1_HUMAN relationship: has_participant CCO:B0054468 ! ZBT43_HUMAN [Term] id: CCO:I0015540 name: cdc42ep1-mapkap1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027730 ! SIN1_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:I0015541 name: cbx2-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0056013 ! CBX2_HUMAN [Term] id: CCO:I0015542 name: ap2m1-tbc1d5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058070 ! TBCD5_HUMAN relationship: has_participant CCO:B0062824 ! AP2M1_HUMAN [Term] id: CCO:I0015543 name: bad-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005175 ! BAD_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN [Term] id: CCO:I0015544 name: scand1-znf167 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019498 ! SCND1_HUMAN relationship: has_participant CCO:B0059030 ! ZN167_HUMAN [Term] id: CCO:I0015545 name: dpcd-ruvbl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757783 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0062924 ! DPCD_HUMAN [Term] id: CCO:I0015546 name: hddc3-nmi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757795 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0062925 ! HDDC3_HUMAN [Term] id: CCO:I0015547 name: scand1-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757801 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005297 ! ZN263_HUMAN relationship: has_participant CCO:B0019498 ! SCND1_HUMAN [Term] id: CCO:I0015548 name: mdfi-znf417 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0057893 ! ZN417_HUMAN [Term] id: CCO:I0015549 name: dkfzp564j157-sdcbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058662 ! SDCB2_HUMAN relationship: has_participant CCO:B0062926 ! PRR13_HUMAN [Term] id: CCO:I0015550 name: mdfi-zfab physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062927 ! Q9Y260_HUMAN [Term] id: CCO:I0015551 name: dazap2-hgs physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757855 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0015552 name: hnrpk-khdrbs3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757876 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN [Term] id: CCO:I0015553 name: mdfi-pvrl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062928 ! PVRL2_HUMAN [Term] id: CCO:I0015554 name: znf24-znf434 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0062898 ! Q9BU74_HUMAN [Term] id: CCO:I0015555 name: ccdc7-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0019119 ! CCDC7_HUMAN [Term] id: CCO:I0015556 name: bene-creb3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757906 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0062929 ! MALL_HUMAN [Term] id: CCO:I0015557 name: ewsr1-mrps18b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062930 ! RT18B_HUMAN [Term] id: CCO:I0015558 name: ndp52-smarcd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0015559 name: rab33a-rtn3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757924 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041728 ! RTN3_HUMAN relationship: has_participant CCO:B0055956 ! RB33A_HUMAN [Term] id: CCO:I0015560 name: efs-scam_1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757930 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028938 ! EFS_HUMAN relationship: has_participant CCO:B0062920 ! Q96FY4_HUMAN [Term] id: CCO:I0015561 name: ndp52-tceb3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757939 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026268 ! CACO2_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015562 name: ap2b1-terf2ip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005197 ! AP2B1_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN [Term] id: CCO:I0015563 name: nono-znrd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005622 ! RPA12_HUMAN [Term] id: CCO:I0015564 name: il1f5-ssbp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005205 ! IL1F5_HUMAN relationship: has_participant CCO:B0055656 ! SSBP2_HUMAN [Term] id: CCO:I0015565 name: dvl2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN [Term] id: CCO:I0015566 name: cdc42ep1-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN [Term] id: CCO:I0015567 name: eif4el3-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0054567 ! IF4E2_HUMAN [Term] id: CCO:I0015568 name: bnip3-bnip3l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-757996 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:I0015569 name: gfap-grap2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN relationship: has_participant CCO:B0062814 ! GFAP_HUMAN [Term] id: CCO:I0015570 name: lrch4-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0054634 ! LRCH4_HUMAN [Term] id: CCO:I0015571 name: plekhf2-tsc22d3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758020 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0058425 ! T22D3_HUMAN [Term] id: CCO:I0015572 name: nif3l1-s100a1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0015573 name: drr1-hook2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054816 ! F107A_HUMAN relationship: has_participant CCO:B0062809 ! HOOK2_HUMAN [Term] id: CCO:I0015574 name: eya2-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758047 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0054293 ! EYA2_HUMAN [Term] id: CCO:I0015575 name: drap1-taf9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758059 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0015576 name: arhgap9-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0058496 ! RHG09_HUMAN [Term] id: CCO:I0015577 name: trim23-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758071 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005214 ! ZN581_HUMAN relationship: has_participant CCO:B0055308 ! ARD1_HUMAN [Term] id: CCO:I0015578 name: actn1-magea11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758080 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0015579 name: gabpb2-mageb18 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758089 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005185 ! MAGBI_HUMAN relationship: has_participant CCO:B0040683 ! GABP1_HUMAN [Term] id: CCO:I0015580 name: mbip-plekhf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758095 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN [Term] id: CCO:I0015581 name: dr1-pole3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758098 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0055692 ! NC2B_HUMAN [Term] id: CCO:I0015582 name: krtap4_12-znf165 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758107 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015583 name: c1orf89-flj22688 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758116 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058517 ! CA089_HUMAN relationship: has_participant CCO:B0062931 ! FUZZY_HUMAN [Term] id: CCO:I0015584 name: trim37-znf417 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0057893 ! ZN417_HUMAN [Term] id: CCO:I0015585 name: cep70-nrip1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN relationship: has_participant CCO:B0062785 ! CEP70_HUMAN [Term] id: CCO:I0015586 name: ndp52-znf426 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026268 ! CACO2_HUMAN relationship: has_participant CCO:B0058524 ! ZN426_HUMAN [Term] id: CCO:I0015587 name: c6_1a-snapc5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758140 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0042518 ! BRCC3_HUMAN relationship: has_participant CCO:B0054683 ! SNPC5_HUMAN [Term] id: CCO:I0015588 name: rxrb-spop physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758155 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005292 ! SPOP_HUMAN relationship: has_participant CCO:B0024878 ! RXRB_HUMAN [Term] id: CCO:I0015589 name: mdfi-znf440 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758158 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0057388 ! ZN440_HUMAN [Term] id: CCO:I0015590 name: kiaa1849-magea11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0058240 ! RADIL_HUMAN [Term] id: CCO:I0015591 name: cops4-mbip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758182 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0022200 ! CSN4_HUMAN [Term] id: CCO:I0015592 name: lmo3-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758185 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015593 name: nono-nono physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005234 ! NONO_HUMAN [Term] id: CCO:I0015594 name: dvl2-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758209 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005297 ! ZN263_HUMAN [Term] id: CCO:I0015595 name: plscr1-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758233 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005214 ! ZN581_HUMAN relationship: has_participant CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:I0015596 name: ndp52-sri physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758236 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026103 ! SORCN_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0015597 name: actg1-dstn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758245 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015628 ! ACTG_HUMAN relationship: has_participant CCO:B0033316 ! DEST_HUMAN [Term] id: CCO:I0015598 name: plekhf2-prkar1a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758269 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0005298 ! KAP0_HUMAN [Term] id: CCO:I0015599 name: dvl2-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758272 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN [Term] id: CCO:I0015600 name: ldb1-tollip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0057244 ! LDB1_HUMAN [Term] id: CCO:I0015601 name: krt15-rhpn1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758308 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0057918 ! RHPN1_HUMAN [Term] id: CCO:I0015602 name: rtn4-spg21 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758314 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:I0015603 name: gorasp2-pcbd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758317 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005241 ! GORS2_HUMAN relationship: has_participant CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:I0015604 name: ehmt2-thap7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0051938 ! EHMT2_HUMAN relationship: has_participant CCO:B0058511 ! THAP7_HUMAN [Term] id: CCO:I0015605 name: ciapin1-txnl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758329 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019428 ! CPIN1_HUMAN relationship: has_participant CCO:B0062932 ! GLRX3_HUMAN [Term] id: CCO:I0015606 name: hoxa9-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758332 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0055236 ! HXA9_HUMAN [Term] id: CCO:I0015607 name: c16orf48-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758338 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062810 ! CP048_HUMAN [Term] id: CCO:I0015608 name: drr1-krt15 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015609 name: ewsr1-tspan3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758353 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062933 ! TSN3_HUMAN [Term] id: CCO:I0015610 name: ctbp2-nrip1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:I0015611 name: eif3s5-hs1bp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758371 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026277 ! EIF3F_HUMAN relationship: has_participant CCO:B0062934 ! HAX1_HUMAN [Term] id: CCO:I0015612 name: nck2-sf3b4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0062935 ! SF3B4_HUMAN [Term] id: CCO:I0015613 name: kctd13-myst2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0058049 ! KCD13_HUMAN [Term] id: CCO:I0015614 name: mgc3162-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005282 ! NOC4L_HUMAN [Term] id: CCO:I0015615 name: drg2-rwdd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758401 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055522 ! DRG2_HUMAN relationship: has_participant CCO:B0062936 ! RWDD1_HUMAN [Term] id: CCO:I0015616 name: gfap-pdzk1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025068 ! PDZD1_HUMAN relationship: has_participant CCO:B0062814 ! GFAP_HUMAN [Term] id: CCO:I0015617 name: efemp2-hoxa1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0015618 name: ewsr1-ggabp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062937 ! CCD91_HUMAN [Term] id: CCO:I0015619 name: rgs14-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0033332 ! RGS14_HUMAN [Term] id: CCO:I0015620 name: begain-drr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015621 name: ipo11-plcd4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024299 ! IPO11_HUMAN relationship: has_participant CCO:B0058489 ! PLCD4_HUMAN [Term] id: CCO:I0015622 name: cry1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0056142 ! CRY1_HUMAN [Term] id: CCO:I0015623 name: nif3l1-rabac1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062819 ! PRAF1_HUMAN [Term] id: CCO:I0015624 name: hey2-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0059081 ! HEY2_HUMAN [Term] id: CCO:I0015625 name: mgc12538-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062938 ! YA004_HUMAN [Term] id: CCO:I0015626 name: efemp2-znf426 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758467 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0058524 ! ZN426_HUMAN [Term] id: CCO:I0015627 name: ldoc1-smarcd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN [Term] id: CCO:I0015628 name: begain-zfp64 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005626 ! BEGIN_HUMAN relationship: has_participant CCO:B0037138 ! ZF64B_HUMAN [Term] id: CCO:I0015629 name: ndp52-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758476 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0026268 ! CACO2_HUMAN [Term] id: CCO:I0015630 name: ppie-xab2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041548 ! SYF1_HUMAN relationship: has_participant CCO:B0059255 ! PPIE_HUMAN [Term] id: CCO:I0015631 name: cart1-ipo13 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056097 ! ALX1_HUMAN relationship: has_participant CCO:B0062870 ! IPO13_HUMAN [Term] id: CCO:I0015632 name: col4a3bp-itgb3bp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758515 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:I0015633 name: krtap4_12-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015634 name: bsg-pdlim7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758533 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005224 ! PDLI7_HUMAN relationship: has_participant CCO:B0055296 ! BASI_HUMAN [Term] id: CCO:I0015635 name: dvl2-loc90268 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062939 ! F105B_HUMAN [Term] id: CCO:I0015636 name: flj12529-hrmt1l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:I0015637 name: birc2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN [Term] id: CCO:I0015638 name: scand1-znf165 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019498 ! SCND1_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015639 name: ewsr1-trim37 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758560 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005249 ! TRI37_HUMAN [Term] id: CCO:I0015640 name: pdcd6-pdcd6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054618 ! PDCD6_HUMAN [Term] id: CCO:I0015641 name: rbm9-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758584 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0015642 name: ehmt2-klf12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0051938 ! EHMT2_HUMAN relationship: has_participant CCO:B0059366 ! KLF12_HUMAN [Term] id: CCO:I0015643 name: mdfi-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005214 ! ZN581_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0015644 name: klrg1-leprotl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058202 ! KLRG1_HUMAN relationship: has_participant CCO:B0062940 ! LERL1_HUMAN [Term] id: CCO:I0015645 name: ewsr1-ntng2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062941 ! NTNG2_HUMAN [Term] id: CCO:I0015646 name: q96br9-zfp276 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057470 ! ZN276_HUMAN relationship: has_participant CCO:B0062820 ! Q96BR9_HUMAN [Term] id: CCO:I0015647 name: krtap4_12-znf655 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0058476 ! Q9BQ85_HUMAN [Term] id: CCO:I0015648 name: trim39-ube2d3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758647 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019461 ! UB2D3_HUMAN relationship: has_participant CCO:B0043417 ! TRI39_HUMAN [Term] id: CCO:I0015649 name: magea11-rfp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0005981 ! TRI27_HUMAN [Term] id: CCO:I0015650 name: ap1m1-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062862 ! AP1M1_HUMAN [Term] id: CCO:I0015651 name: hgs-stam2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758680 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0062916 ! STAM2_HUMAN [Term] id: CCO:I0015652 name: nif3l1-snf8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758689 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0018982 ! SNF8_HUMAN [Term] id: CCO:I0015653 name: hoxb9-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758692 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0036838 ! HXB9_HUMAN [Term] id: CCO:I0015654 name: ewsr1-flj12529 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:I0015655 name: nup62-thap1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758710 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0062880 ! THAP1_HUMAN [Term] id: CCO:I0015656 name: bag3-hspb8-1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024107 ! HSPB8_HUMAN relationship: has_participant CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:I0015657 name: syt17-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0040086 ! SYT17_HUMAN [Term] id: CCO:I0015658 name: csrp2bp-mbip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0062942 ! CSR2B_HUMAN [Term] id: CCO:I0015659 name: lasp1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062943 ! LASP1_HUMAN [Term] id: CCO:I0015660 name: bag3-dazap2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758755 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0054796 ! BAG3_HUMAN [Term] id: CCO:I0015661 name: nmi-q96ih6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0062944 ! Q96IH6_HUMAN [Term] id: CCO:I0015662 name: hoxa1-lpxn physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758764 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017845 ! LPXN_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0015663 name: bnip3l-tmem11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN relationship: has_participant CCO:B0055084 ! TMM11_HUMAN [Term] id: CCO:I0015664 name: drr1-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015665 name: grap2-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758785 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN [Term] id: CCO:I0015666 name: crsp9-hgs physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN [Term] id: CCO:I0015667 name: mdfi-mgc13138 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005276 ! ZN764_HUMAN [Term] id: CCO:I0015668 name: tead3-wwtr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032261 ! TEAD3_HUMAN relationship: has_participant CCO:B0058638 ! WWTR1_HUMAN [Term] id: CCO:I0015669 name: nrip1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758842 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN [Term] id: CCO:I0015670 name: nfkbia-pom121 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758848 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0061984 ! P121A_HUMAN [Term] id: CCO:I0015671 name: ercc1-sb132 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758851 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015646 ! ERCC1_HUMAN relationship: has_participant CCO:B0062945 ! UBL7_HUMAN [Term] id: CCO:I0015672 name: abi3-kiaa0470l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038093 ! ABI3_HUMAN relationship: has_participant CCO:B0062851 ! C170L_HUMAN [Term] id: CCO:I0015673 name: ewsr1-seli physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0051832 ! Q8WU57_HUMAN [Term] id: CCO:I0015674 name: mgc2749-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005184 ! CS050_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015675 name: mdfi-theg physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062946 ! THEG_HUMAN [Term] id: CCO:I0015676 name: dvl2-scam_1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062920 ! Q96FY4_HUMAN [Term] id: CCO:I0015677 name: ewsr1-myl6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758914 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:I0015678 name: ndp52-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026268 ! CACO2_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015679 name: krtap4_12-znf581 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005214 ! ZN581_HUMAN relationship: has_participant CCO:B0005293 ! KR412_HUMAN [Term] id: CCO:I0015680 name: ewsr1-smad4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758962 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN [Term] id: CCO:I0015681 name: pepp2-sfrs16 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:I0015682 name: hmg20a-hpcal1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758971 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005296 ! HM20A_HUMAN relationship: has_participant CCO:B0062908 ! HPCL1_HUMAN [Term] id: CCO:I0015683 name: heyl-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758974 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0058865 ! HEYL_HUMAN [Term] id: CCO:I0015684 name: magea11-tcea2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0015685 name: gabpb2-tdrd7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758980 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005496 ! TDRD7_HUMAN relationship: has_participant CCO:B0040683 ! GABP1_HUMAN [Term] id: CCO:I0015686 name: mgc4504-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758989 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0062948 ! CHAC1_HUMAN [Term] id: CCO:I0015687 name: nif3l1-xtp3tpa physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-758995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062949 ! XTP3A_HUMAN [Term] id: CCO:I0015688 name: nme7-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005294 ! NDK7_HUMAN relationship: has_participant CCO:B0005297 ! ZN263_HUMAN [Term] id: CCO:I0015689 name: hnrpk-rbmx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005256 ! HNRPG_HUMAN [Term] id: CCO:I0015690 name: ppp1r16a-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0039979 ! PP16A_HUMAN [Term] id: CCO:I0015691 name: sp100-sumo1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN relationship: has_participant CCO:B0055159 ! SP100_HUMAN [Term] id: CCO:I0015692 name: ewsr1-tmsb4y physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759067 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0049176 ! TYB4Y_HUMAN [Term] id: CCO:I0015693 name: nck2-wbp11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005313 ! WBP11_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:I0015694 name: efemp2-rhpn1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0057918 ! RHPN1_HUMAN [Term] id: CCO:I0015695 name: nif3l1-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015696 name: cbfa2t2-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0054482 ! MTG8R_HUMAN [Term] id: CCO:I0015697 name: gem-pdlim7 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005224 ! PDLI7_HUMAN relationship: has_participant CCO:B0055523 ! GEM_HUMAN [Term] id: CCO:I0015698 name: ewsr1-q8n4c1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062950 ! Q8N4C1_HUMAN [Term] id: CCO:I0015699 name: mdfi-znf101 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062951 ! Q96F93_HUMAN [Term] id: CCO:I0015700 name: fth1-ftl physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006192 ! FRIL_HUMAN relationship: has_participant CCO:B0033704 ! FRIH_HUMAN [Term] id: CCO:I0015701 name: c1orf116-homer1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057307 ! HOME1_HUMAN relationship: has_participant CCO:B0062952 ! Q9BPY1_HUMAN [Term] id: CCO:I0015702 name: appbp2-chmp5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759175 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059023 ! CHMP5_HUMAN relationship: has_participant CCO:B0062805 ! APBP2_HUMAN [Term] id: CCO:I0015703 name: nif3l1-pcbd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:I0015704 name: tsc22d4-ublcp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005278 ! UBCP1_HUMAN [Term] id: CCO:I0015705 name: mgc13138-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759202 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005276 ! ZN764_HUMAN relationship: has_participant CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:I0015706 name: plekhf2-znf263 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0005297 ! ZN263_HUMAN [Term] id: CCO:I0015707 name: pdlim7-znf165 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005224 ! PDLI7_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015708 name: ewsr1-mvk physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062953 ! KIME_HUMAN [Term] id: CCO:I0015709 name: eps8-hook2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759226 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0062809 ! HOOK2_HUMAN [Term] id: CCO:I0015710 name: krtap4_12-pdgfrb physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN [Term] id: CCO:I0015711 name: irf4-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759244 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0056056 ! IRF4_HUMAN [Term] id: CCO:I0015712 name: c14orf32-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0041276 ! MISSL_HUMAN [Term] id: CCO:I0015713 name: dnpep-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062954 ! DNPEP_HUMAN [Term] id: CCO:I0015714 name: trim41-znf473 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057971 ! ZN473_HUMAN relationship: has_participant CCO:B0062904 ! TRI41_HUMAN [Term] id: CCO:I0015715 name: nmi-snapc5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0054683 ! SNPC5_HUMAN [Term] id: CCO:I0015716 name: hmg20a-hmg20a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005296 ! HM20A_HUMAN [Term] id: CCO:I0015717 name: aqp1-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759289 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0034159 ! AQP1_HUMAN [Term] id: CCO:I0015718 name: drr1-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759292 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015719 name: ewsr1-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759295 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN [Term] id: CCO:I0015720 name: krt15-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005207 ! K1C15_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015721 name: dvl2-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0015722 name: meox2-vip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005623 ! MEOX2_HUMAN relationship: has_participant CCO:B0054849 ! VIP_HUMAN [Term] id: CCO:I0015723 name: scand1-znf24 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759331 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0019498 ! SCND1_HUMAN [Term] id: CCO:I0015724 name: hnrpk-hqk physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0058345 ! QKI_HUMAN [Term] id: CCO:I0015725 name: ewsr1-mtmr9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0026696 ! MTMR9_HUMAN [Term] id: CCO:I0015726 name: ndp52-rhpn1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026268 ! CACO2_HUMAN relationship: has_participant CCO:B0057918 ! RHPN1_HUMAN [Term] id: CCO:I0015727 name: efemp2-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759367 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0015728 name: hif1an-invs physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759370 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058941 ! HIF1N_HUMAN relationship: has_participant CCO:B0059298 ! INVS_HUMAN [Term] id: CCO:I0015729 name: runx1t1-wbp11 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759376 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005313 ! WBP11_HUMAN relationship: has_participant CCO:B0055769 ! MTG8_HUMAN [Term] id: CCO:I0015730 name: hnrpm-lmo3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759379 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057890 ! LMO3_HUMAN relationship: has_participant CCO:B0062955 ! HNRPM_HUMAN [Term] id: CCO:I0015731 name: ewsr1-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759382 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:I0015732 name: cep70-tceb3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759385 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN relationship: has_participant CCO:B0062785 ! CEP70_HUMAN [Term] id: CCO:I0015733 name: dvl2-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759388 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0055041 ! ZN250_HUMAN [Term] id: CCO:I0015734 name: csen-prv1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020218 ! CSEN_HUMAN relationship: has_participant CCO:B0062866 ! CD177_HUMAN [Term] id: CCO:I0015735 name: znf193-znf446 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005269 ! Q96AF5_HUMAN relationship: has_participant CCO:B0054446 ! ZN193_HUMAN [Term] id: CCO:I0015736 name: hpcal4-tsc22d3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058425 ! T22D3_HUMAN relationship: has_participant CCO:B0062823 ! HPCL4_HUMAN [Term] id: CCO:I0015737 name: hgs-ubqln1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005181 ! UBQL1_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN [Term] id: CCO:I0015738 name: rnf126-ube2d3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019461 ! UB2D3_HUMAN relationship: has_participant CCO:B0043418 ! RN126_HUMAN [Term] id: CCO:I0015739 name: hoxb9-sat physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006107 ! SAT1_HUMAN relationship: has_participant CCO:B0036838 ! HXB9_HUMAN [Term] id: CCO:I0015740 name: birc4-birc4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759427 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0015741 name: kiaa1683-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005254 ! K1683_HUMAN relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:I0015742 name: ewsr1-pdhx physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062956 ! ODPX_HUMAN [Term] id: CCO:I0015743 name: mdfi-phlda1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759457 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062957 ! PHLA1_HUMAN [Term] id: CCO:I0015744 name: c10orf12-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062958 ! CJ012_HUMAN [Term] id: CCO:I0015745 name: gorasp2-nup62 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005241 ! GORS2_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN [Term] id: CCO:I0015746 name: krtap4_12-tceb3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015747 name: c8orf48-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0062959 ! CH048_HUMAN [Term] id: CCO:I0015748 name: tcea2-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759493 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0015749 name: drap1-taf9l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759496 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0014928 ! TAF9B_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0015750 name: dtnb-hmg20a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759505 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005296 ! HM20A_HUMAN relationship: has_participant CCO:B0030221 ! Q96AW0_HUMAN [Term] id: CCO:I0015751 name: chic2-otx1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020052 ! CHIC2_HUMAN relationship: has_participant CCO:B0055254 ! OTX1_HUMAN [Term] id: CCO:I0015752 name: trim23-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055041 ! ZN250_HUMAN relationship: has_participant CCO:B0055308 ! ARD1_HUMAN [Term] id: CCO:I0015753 name: cutc-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005203 ! Q96BX3_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN [Term] id: CCO:I0015754 name: ewsr1-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0015755 name: hca66-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0006050 ! UTP6_HUMAN [Term] id: CCO:I0015756 name: cbx5-tceb3b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0015757 name: gage8-gmcl1l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033871 ! GAGE8_HUMAN relationship: has_participant CCO:B0057588 ! GMCLL_HUMAN [Term] id: CCO:I0015758 name: hnrpk-scam_1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0062920 ! Q96FY4_HUMAN [Term] id: CCO:I0015759 name: rfx3-rfxdc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759562 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028073 ! RFX3_HUMAN relationship: has_participant CCO:B0061983 ! RFX6_HUMAN [Term] id: CCO:I0015760 name: hnrpc-lmo3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015761 name: arfip2-itgb3bp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759571 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0015762 name: dazap2-wwp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759577 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0058653 ! WWP1_HUMAN [Term] id: CCO:I0015763 name: myd88-spop physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759580 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005292 ! SPOP_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0015764 name: q96br9-znf408 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759583 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0062820 ! Q96BR9_HUMAN [Term] id: CCO:I0015765 name: q8n2x6-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759589 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0062911 ! YE036_HUMAN [Term] id: CCO:I0015766 name: krtap4_12-znf440 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759604 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0057388 ! ZN440_HUMAN [Term] id: CCO:I0015767 name: hgs-tada2l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005318 ! Q9BVJ0_HUMAN [Term] id: CCO:I0015768 name: rab33a-rtn4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0055956 ! RB33A_HUMAN [Term] id: CCO:I0015769 name: q96br9-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759628 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055041 ! ZN250_HUMAN relationship: has_participant CCO:B0062820 ! Q96BR9_HUMAN [Term] id: CCO:I0015770 name: crx-mdfi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0054456 ! CRX_HUMAN [Term] id: CCO:I0015771 name: ewsr1-sall2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062886 ! Q8N656_HUMAN [Term] id: CCO:I0015772 name: otx1-rbpms physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0055254 ! OTX1_HUMAN [Term] id: CCO:I0015773 name: ap1m1-ldoc1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0062862 ! AP1M1_HUMAN [Term] id: CCO:I0015774 name: pde9a-pde9a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054693 ! PDE9A_HUMAN [Term] id: CCO:I0015775 name: cntfr-plscr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026846 ! CNTFR_HUMAN relationship: has_participant CCO:B0038636 ! PLS1_HUMAN [Term] id: CCO:I0015776 name: nudt3-sox30 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020266 ! SOX30_HUMAN relationship: has_participant CCO:B0026419 ! NUDT3_HUMAN [Term] id: CCO:I0015777 name: dnaja3-znf297 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759691 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN relationship: has_participant CCO:B0054415 ! ZBT22_HUMAN [Term] id: CCO:I0015778 name: acp1-sfmbt1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759694 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022236 ! PPAC_HUMAN relationship: has_participant CCO:B0059142 ! SMBT1_HUMAN [Term] id: CCO:I0015779 name: max-plekhf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759715 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005194 ! PKHF2_HUMAN relationship: has_participant CCO:B0058187 ! Q96CY8_HUMAN [Term] id: CCO:I0015780 name: dctd-nif3l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0062960 ! DCTD_HUMAN [Term] id: CCO:I0015781 name: mthfs-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0062961 ! MTHFS_HUMAN [Term] id: CCO:I0015782 name: grn-hoxa1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005961 ! GRN_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0015783 name: necap2-nmi physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0062791 ! NECP2_HUMAN [Term] id: CCO:I0015784 name: agt-ewsr1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN [Term] id: CCO:I0015785 name: c8orf32-pcbd1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759769 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005179 ! CH032_HUMAN relationship: has_participant CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:I0015786 name: rad23a-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759772 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:I0015787 name: gnb2l1-tsc22d4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759787 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005739 ! GBLP_HUMAN [Term] id: CCO:I0015788 name: ewsr1-kcnmb1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0062962 ! KCMB1_HUMAN [Term] id: CCO:I0015789 name: lpxn-pom121 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017845 ! LPXN_HUMAN relationship: has_participant CCO:B0061984 ! P121A_HUMAN [Term] id: CCO:I0015790 name: magea11-znf655 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759805 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0058476 ! Q9BQ85_HUMAN [Term] id: CCO:I0015791 name: pepp2-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759823 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0015792 name: optn-tbc1d17 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0030838 ! OPTN_HUMAN [Term] id: CCO:I0015793 name: etnk2-nol3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054591 ! NOL3_HUMAN relationship: has_participant CCO:B0062963 ! Q96G05_HUMAN [Term] id: CCO:I0015794 name: mdfi-tcfl1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759874 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN [Term] id: CCO:I0015795 name: trip6-vcl physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0043439 ! VINC_HUMAN [Term] id: CCO:I0015796 name: ogt-rp13_383k5_2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759952 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005806 ! OGT1_HUMAN relationship: has_participant CCO:B0021714 ! N62CL_HUMAN [Term] id: CCO:I0015797 name: hhgp-hprt1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759970 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032831 ! PRDC1_HUMAN relationship: has_participant CCO:B0036957 ! HPRT_HUMAN [Term] id: CCO:I0015798 name: hoxa1-trip6 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759973 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN [Term] id: CCO:I0015799 name: cova1-flj10094 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056127 ! ENOX2_HUMAN relationship: has_participant CCO:B0062800 ! ENOX1_HUMAN [Term] id: CCO:I0015800 name: magea11-med28 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-759985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN [Term] id: CCO:I0015801 name: dvl2-znf165 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015802 name: cxorf2-eps8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760018 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0062964 ! TEX28_HUMAN [Term] id: CCO:I0015803 name: znf202-znf473 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760024 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054725 ! ZN202_HUMAN relationship: has_participant CCO:B0057971 ! ZN473_HUMAN [Term] id: CCO:I0015804 name: lmo3-mbip physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0015805 name: drr1-ndp52 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026268 ! CACO2_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN [Term] id: CCO:I0015806 name: fam46b-pepp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0062965 ! FA46B_HUMAN [Term] id: CCO:I0015807 name: mgc39520-rab2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055602 ! RAB2A_HUMAN relationship: has_participant CCO:B0062966 ! FA71C_HUMAN [Term] id: CCO:I0015808 name: znf165-znf250 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055041 ! ZN250_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0015809 name: col4a3bp-rtn4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760099 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0062891 ! C43BP_HUMAN [Term] id: CCO:I0015810 name: flj22875-wdr39 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054691 ! CIAO1_HUMAN relationship: has_participant CCO:B0062967 ! FA96A_HUMAN [Term] id: CCO:I0015811 name: dvl2-dvl2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760123 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN [Term] id: CCO:I0015812 name: dvl2-thap1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0062880 ! THAP1_HUMAN [Term] id: CCO:I0015813 name: runx1t1-taf9l physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0014928 ! TAF9B_HUMAN relationship: has_participant CCO:B0055769 ! MTG8_HUMAN [Term] id: CCO:I0015814 name: cntfr-krtap4_12 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0026846 ! CNTFR_HUMAN [Term] id: CCO:I0015815 name: bnip2-creb3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760141 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0005677 ! BNIP2_HUMAN [Term] id: CCO:I0015816 name: flj12529-nck2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760153 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:I0015817 name: nol4-snapc5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760159 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054683 ! SNPC5_HUMAN relationship: has_participant CCO:B0062875 ! NOL4_HUMAN [Term] id: CCO:I0015818 name: nmi-tuba2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760171 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0015819 name: exoc7-prp19 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760180 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016149 ! PRP19_HUMAN relationship: has_participant CCO:B0062769 ! EXOC7_HUMAN [Term] id: CCO:I0015820 name: tifa-traf2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760201 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062825 ! TIFA_HUMAN [Term] id: CCO:I0015821 name: rfc4-rfc5 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN [Term] id: CCO:I0015822 name: bnip3-bnip3 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN [Term] id: CCO:I0015823 name: akap10-prkar1a physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0054493 ! AKA10_HUMAN [Term] id: CCO:I0015824 name: ralb-ralbp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054989 ! RALB_HUMAN relationship: has_participant CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:I0015825 name: rab1a-rabac1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0062819 ! PRAF1_HUMAN [Term] id: CCO:I0015826 name: max-mxi1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058187 ! Q96CY8_HUMAN relationship: has_participant CCO:B0058201 ! Q96E53_HUMAN [Term] id: CCO:I0015827 name: bcl2l1-bik physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760279 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0015828 name: grap2-stambp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN relationship: has_participant CCO:B0054776 ! STABP_HUMAN [Term] id: CCO:I0015829 name: stam2-stambp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0062916 ! STAM2_HUMAN [Term] id: CCO:I0015830 name: eif4e-eif4ebp1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:I0015831 name: actn1-myoz physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760306 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005306 ! MYOZ1_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0015832 name: golga2-rab2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN relationship: has_participant CCO:B0055602 ! RAB2A_HUMAN [Term] id: CCO:I0015833 name: ring1-rybp physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020553 ! RING1_HUMAN relationship: has_participant CCO:B0057465 ! RYBP_HUMAN [Term] id: CCO:I0015834 name: baiap2-eps8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:I0015835 name: pdcd6-pef1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006326 ! PEF1_HUMAN relationship: has_participant CCO:B0054618 ! PDCD6_HUMAN [Term] id: CCO:I0015836 name: hnrpk-nck2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760330 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:I0015837 name: hgs-stam physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760333 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0058093 ! STAM1_HUMAN [Term] id: CCO:I0015838 name: eps8-eps8 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019772 ! EPS8_HUMAN [Term] id: CCO:I0015839 name: birc4-casp9 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760345 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0015840 name: bhmt-bhmt physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058123 ! BHMT1_HUMAN [Term] id: CCO:I0015841 name: s100a1-s100b physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760357 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0015842 name: traf2-traf2-4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760360 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0015843 name: arl2-pde6d physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760372 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006130 ! PDE6D_HUMAN relationship: has_participant CCO:B0055307 ! ARL2_HUMAN [Term] id: CCO:I0015844 name: arhgap1-rhoa physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN [Term] id: CCO:I0015845 name: bak1-bcl2l1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005420 ! BAK_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0015846 name: tceb1-tceb2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN [Term] id: CCO:I0015847 name: rraga-rragc physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0015848 name: tsg101-vps28-1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0062968 ! VPS28_HUMAN [Term] id: CCO:I0015849 name: impa1-impa1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760423 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0042291 ! IMPA1_HUMAN [Term] id: CCO:I0015850 name: hgs-tsg101 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN [Term] id: CCO:I0015851 name: acd-pot1 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005503 ! POTE1_HUMAN relationship: has_participant CCO:B0005504 ! ACD_HUMAN [Term] id: CCO:I0015852 name: s100a1-s100a4 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019310 ! S10A4_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0015853 name: grap2-lcp2 physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN relationship: has_participant CCO:B0055872 ! LCP2_HUMAN [Term] id: CCO:I0015854 name: sri-sri physical interaction comment: Part of the CCSB-H11 dataset. xref: IntAct:EBI-760447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026103 ! SORCN_HUMAN [Term] id: CCO:I0015855 name: arhgap24-flna-6 physical interaction comment: Interaction between ARHGAP24 and FLNA identified by pulldown xref: IntAct:EBI-1004037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0015856 name: stk4-sav1-1 physical interaction comment: Interaction betweenSTK4 (MST1) and STV1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1017784 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005702 ! STK4_HUMAN relationship: has_participant CCO:B0058715 ! SAV1_HUMAN [Term] id: CCO:I0015857 name: hba1-hbb-9 direct interaction comment: Crystal structure of deoxy-human hemoglobin beta6 glu->trp xref: IntAct:EBI-1027413 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0015858 name: fkbp1a-tgfbr1-1 direct interaction comment: Crystal structure of the cytoplasmic domain of the type i tgf-beta receptor in complex with fkbp12 xref: IntAct:EBI-1027593 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005655 ! FKB1A_HUMAN relationship: has_participant CCO:B0020370 ! TGFR1_HUMAN [Term] id: CCO:I0015859 name: hba1-hbb-13 direct interaction comment: Deoxy rhb1.0 (recombinant hemoglobin) xref: IntAct:EBI-1029796 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0015860 name: hba1-hbb-14 direct interaction comment: Deoxy rhb1.1 (recombinant hemoglobin) xref: IntAct:EBI-1029806 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0015861 name: hba1-hbb-15 direct interaction comment: Deoxy rhb1.2 (recombinant hemoglobin) xref: IntAct:EBI-1029816 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0015862 name: ctnnb1-ctnnbip1-6 direct interaction comment: Crystal structure of the beta-catenin-icat complex xref: IntAct:EBI-1034619 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN [Term] id: CCO:I0015863 name: scp2-cav1-3 physical interaction xref: IntAct:EBI-1161455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:I0015864 name: cav1-scp2-3 physical interaction xref: IntAct:EBI-1161464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0062969 ! NLTP_HUMAN [Term] id: CCO:I0015865 name: gsk3b-nin-1 physical interaction comment: Interaction between GSK3B and NIN identified by Y2H xref: IntAct:EBI-1164099 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0062970 ! NIN_HUMAN [Term] id: CCO:I0015866 name: cd247-cd247-3 physical interaction comment: Mutational analysis of residues involved in zeta-zeta dimer formation xref: IntAct:EBI-1166230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:I0015867 name: cd247-cd247-4 physical interaction comment: Mutational analysis of residues involved in zeta-zeta dimer formation xref: IntAct:EBI-1166309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:I0015868 name: tap1-pd1a3-2 direct interaction xref: IntAct:EBI-1168206 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005889 ! TAP1_HUMAN relationship: has_participant CCO:B0042031 ! PDIA3_HUMAN [Term] id: CCO:I0015869 name: rfc1-rfc2-2 physical interaction comment: Reconstitution of the RFC complex xref: IntAct:EBI-1169835 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015870 name: rfc1-rfc2-3 physical interaction comment: Reconstitution of the RFC complex xref: IntAct:EBI-1169881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015871 name: rfc1-rfc2-4 physical interaction comment: Reconstitution of the RFC complex xref: IntAct:EBI-1169912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015872 name: rfc2-rfc3-1 physical interaction comment: Reconstitution of the RFC complex in the absence of RFC1 p140 subunit xref: IntAct:EBI-1169930 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015873 name: rfc2-rfc4-4 physical interaction comment: Reconstitution of the RFC complex in the absence of RFC1 p38 subunit xref: IntAct:EBI-1169991 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015874 name: rfc4-rfc3-2 physical interaction comment: Reconstitution of the RFC complex in the absence of RFC1 p40 subunit xref: IntAct:EBI-1170023 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN [Term] id: CCO:I0015875 name: rfc1-rfc3-1 physical interaction comment: Reconstitution of the RFC complex in the absence of RFC1 p36 subunit xref: IntAct:EBI-1170033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015876 name: rfc4-rfc3-3 physical interaction comment: Interation of RFC4 and RFC 3 identified by pulldown xref: IntAct:EBI-1170043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN [Term] id: CCO:I0015877 name: rfc3-rfc4-1 physical interaction comment: Interaction between RFC3 and RFC4 identified by pulldown xref: IntAct:EBI-1170051 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN [Term] id: CCO:I0015878 name: rfc2-rfc4-5 physical interaction comment: Indirect interaction between RFC2 and RFC4 identified by pulldown xref: IntAct:EBI-1170060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015879 name: rfc4-rfc5-1 physical interaction comment: Interaction of RFC1, RFC4 and RFC5 identified by pulldown xref: IntAct:EBI-1170068 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN [Term] id: CCO:I0015880 name: spink7-mt2a-1 direct interaction comment: GST-ECRG2 pulls down HA-MT2A in vitro xref: IntAct:EBI-1182578 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0062971 ! ISK7_HUMAN [Term] id: CCO:I0015881 name: brm-mecp2-4 physical interaction xref: IntAct:EBI-1189105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:I0015882 name: brm-mecp2-5 physical interaction xref: IntAct:EBI-1189113 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:I0015883 name: max-snip1 physical interaction comment: Max coimmunoprecipitates SNIP1 in HEK293 cell lysate xref: IntAct:EBI-1189176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN relationship: has_participant CCO:B0005336 ! MAX_HUMAN [Term] id: CCO:I0015884 name: xab2-polr2a-1 physical interaction comment: interaction detected by CoIP. xref: IntAct:EBI-295326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0041548 ! SYF1_HUMAN [Term] id: CCO:I0015885 name: polr2a-xab2-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-295330 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0041548 ! SYF1_HUMAN [Term] id: CCO:I0015886 name: prcki-rac1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-295484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN [Term] id: CCO:I0015887 name: prkci-cdc42-1 physical interaction comment: Interaction detected by Y2H : bait = cdc42, prey = PKC iota xref: IntAct:EBI-295488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0015888 name: exosc8-zfp36 physical interaction xref: IntAct:EBI-374307 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005556 ! EXOS8_HUMAN relationship: has_participant CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:I0015889 name: rrp4-znf408-1 physical interaction xref: IntAct:EBI-374313 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039757 ! EXOS2_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015890 name: lsm2-znf408-2 physical interaction xref: IntAct:EBI-374376 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0062972 ! LSM2_HUMAN [Term] id: CCO:I0015891 name: lsm3-xrn2 physical interaction xref: IntAct:EBI-374406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005566 ! LSM3_HUMAN relationship: has_participant CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:I0015892 name: xrn2-pmscl2 physical interaction xref: IntAct:EBI-374491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005348 ! EXOSX_HUMAN relationship: has_participant CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:I0015893 name: xrn2-exosc8 physical interaction xref: IntAct:EBI-374494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005556 ! EXOS8_HUMAN relationship: has_participant CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:I0015894 name: elavl1-elavl1 physical interaction xref: IntAct:EBI-374503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056099 ! ELAV1_HUMAN [Term] id: CCO:I0015895 name: znf408-znf408-1 physical interaction xref: IntAct:EBI-374545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015896 name: znf408-rrp4 physical interaction xref: IntAct:EBI-374551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039757 ! EXOS2_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0015897 name: abi1-ncf1-1 physical interaction comment: Y2H: bait= ncf1, prey=abi1 xref: IntAct:EBI-395065 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:I0015898 name: map3k1-map2k4-1 physical interaction comment: Interaction between MAP3K1 and MAP2K4 demonstrated by co-immunoprecipitation xref: IntAct:EBI-447867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN [Term] id: CCO:I0015899 name: arf1-pscd2-1 physical interaction comment: Gel filtration. Complex between ARNO sec7 domain and Arf1. xref: IntAct:EBI-448973 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015288 ! ARF1_HUMAN relationship: has_participant CCO:B0058410 ! CYH2_HUMAN [Term] id: CCO:I0015900 name: arf1-pscd2-2 physical interaction comment: Gel filtration. Complex between ARNO sec7 domain and Arf1. xref: IntAct:EBI-449040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015288 ! ARF1_HUMAN relationship: has_participant CCO:B0058410 ! CYH2_HUMAN [Term] id: CCO:I0015901 name: cdc42-iqgap1-2 physical interaction comment: GST pull down, Bait = human GST IQGAP1 , Prey =human MBP Cdc42 xref: IntAct:EBI-457815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:I0015902 name: raet1g-klrk1-1 physical interaction comment: Interaction detected by flow cytometry xref: IntAct:EBI-458340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020481 ! RET1G_HUMAN relationship: has_participant CCO:B0055192 ! NKG2D_HUMAN [Term] id: CCO:I0015903 name: prkaca-prkar1a-1 physical interaction xref: IntAct:EBI-476449 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0018543 ! KAPCA_HUMAN [Term] id: CCO:I0015904 name: rfc2-prkar1a-1 physical interaction xref: IntAct:EBI-476475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015905 name: rfc2-prkar1a-2 physical interaction xref: IntAct:EBI-476478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015906 name: prkar1a-rfc2-1 physical interaction xref: IntAct:EBI-476491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015907 name: rfc1-rfc2-1 physical interaction xref: IntAct:EBI-476646 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015908 name: rfc2-rfc4-1 physical interaction xref: IntAct:EBI-476667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0015909 name: ccr5-cxcr4-1 colocalization comment: Colocalisation of human chemokine receptor CCR5 and CXR4 in mouse fibroblast surface xref: IntAct:EBI-489461 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0055474 ! CCR5_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:I0015910 name: adra1a-bmp1-1 physical interaction comment: 2-hybrid: bait = human adrenergic receptor alpha 1a, prey= human BMP-1 xref: IntAct:EBI-489882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038258 ! ADA1A_HUMAN relationship: has_participant CCO:B0062974 ! BMP1_HUMAN [Term] id: CCO:I0015911 name: adra1a-abr-1 physical interaction comment: 2-hybrid: bait = human adrenergic receptor alpha 1a, prey= human ABR xref: IntAct:EBI-489946 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038258 ! ADA1A_HUMAN relationship: has_participant CCO:B0055861 ! ABR_HUMAN [Term] id: CCO:I0015912 name: adra1a-fnlc-1 physical interaction comment: 2-hybrid: bait = human adrenergic receptor alpha 1a, prey= human filamin C xref: IntAct:EBI-489983 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038258 ! ADA1A_HUMAN relationship: has_participant CCO:B0041399 ! FLNC_HUMAN [Term] id: CCO:I0015913 name: map4k5-crk-2 physical interaction comment: MAP4K5 -Crk identified by co-immunoprecipitation xref: IntAct:EBI-492092 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:I0015914 name: map4k1-crkl-2 physical interaction comment: MAP4K1 -CrkL identified by co-immunoprecipitation xref: IntAct:EBI-492117 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:I0015915 name: map4k1-crkl-3 physical interaction comment: MAP4K1 -CrkL identified by co-immunoprecipitation xref: IntAct:EBI-492149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:I0015916 name: map4k5-crk-4 physical interaction comment: MAP4K5 -Crk identified by GST pull-down xref: IntAct:EBI-492246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:I0015917 name: map4k1-crkl-6 physical interaction comment: MAP4K1 -CrkL identified by co-immunoprecipitation xref: IntAct:EBI-492272 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:I0015918 name: abi1-ncf1-3 physical interaction comment: Y2H: bait= ncf1; prey= p47 phox xref: IntAct:EBI-494022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:I0015919 name: abi1-ncf1-4 physical interaction comment: Y2H: bait= ncf1; prey= p47 phox xref: IntAct:EBI-494028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:I0015920 name: tnfrsf6-fadd-1 physical interaction comment: Interaction between FasLR and FADD identified by Y2H xref: IntAct:EBI-494817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0015921 name: map4k2-mekk1-2 physical interaction comment: Human MAP4K2-MEKK1 co-immunoprecipitation xref: IntAct:EBI-49795 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005706 ! M4K2_HUMAN [Term] id: CCO:I0015922 name: tnfsf10-tnfrs10b-1 physical interaction comment: streptavidin pull-down with biotinylated TRAIL : TRAIL DISC complex xref: IntAct:EBI-518964 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0015923 name: atar-traf5-3 physical interaction comment: Yeast-2-hybrid reveals interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (ATAR) and the TNF receptor associated factor 5 protein (TRAF5) xref: IntAct:EBI-523952 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN [Term] id: CCO:I0015924 name: atar-traf5-4 physical interaction comment: Yeast-2-hybrid reveals interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (ATAR) and the TNF receptor associated factor 5 protein (TRAF5) xref: IntAct:EBI-523991 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN [Term] id: CCO:I0015925 name: atar-traf2-9 physical interaction comment: Yeast-2-hybrid reveals interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (ATAR) and the TNF receptor associated factor 2 protein (TRAF2) xref: IntAct:EBI-524003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005707 ! TNR14_HUMAN [Term] id: CCO:I0015926 name: irak-traf6 physical interaction comment: Coimmunoprecipitation revels interaction between the Interleukin-1 receptor-associated kinase 1 (IRAK1) protein and the TNF receptor associated factor 6 (TRAF6) protein xref: IntAct:EBI-524984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:I0015927 name: rank-traf2 physical interaction comment: FLAG tag reveals interaction between tumor necrosis factor receptor superfamily member 11A precursor and TNF receptor associated factor 2 xref: IntAct:EBI-525685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0059413 ! TNR11_HUMAN [Term] id: CCO:I0015928 name: rank-traf5 physical interaction comment: FLAG tag reveals interaction between tumor necrosis factor receptor superfamily member 11A precursor and TNF receptor associated factor 5 xref: IntAct:EBI-525692 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN relationship: has_participant CCO:B0059413 ! TNR11_HUMAN [Term] id: CCO:I0015929 name: rank-traf6 physical interaction comment: FLAG tag reveals interaction between tumor necrosis factor receptor superfamily member 11A precursor and TNF receptor associated factor 6 xref: IntAct:EBI-525702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0059413 ! TNR11_HUMAN [Term] id: CCO:I0015930 name: ikbkg-chuk-3 physical interaction comment: Coimmunoprecipitation reveals interaction between the NF-kappa-B essential modulator (NEMO) protein and the Inhibitor of nuclear factor kappa-B kinase alpha subunit (IKK_alpha) xref: IntAct:EBI-528444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0015931 name: ikbkg-chuk-1 physical interaction comment: Coimmunoprecipitation reveals interaction between the Inhibitor of nuclear factor kappa-B kinase alpha subunit (IKK_alpha) and the NF-kappa-B essential modulator (NEMO) protein xref: IntAct:EBI-528450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0015932 name: edar-traf3 physical interaction comment: Coimmunoprecipitation reveals interaction between the Tumor necrosis factor receptor superfamily member EDAR precursor and TNF receptor associated factor 3 (TRAF3) xref: IntAct:EBI-529350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0059250 ! EDAR_HUMAN [Term] id: CCO:I0015933 name: edar-nik physical interaction comment: Coimmunoprecipitation reveals interaction between the Tumor necrosis factor receptor superfamily member EDAR precursor and Mitogen-activated protein kinase kinase kinase 14 (NIK) xref: IntAct:EBI-529386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0059250 ! EDAR_HUMAN [Term] id: CCO:I0015934 name: edar-eda physical interaction comment: Coimmunoprecipitation reveals that Ectodysplasin A (EDA) is the ligand of the Tumor necrosis factor receptor superfamily member EDAR precursor xref: IntAct:EBI-529482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058102 ! EDA_HUMAN relationship: has_participant CCO:B0059250 ! EDAR_HUMAN [Term] id: CCO:I0015935 name: itpr1-txndc4-2 physical interaction comment: Interaction between ITPR1 and TXNDC4 demonstrated by coimmunoprecipitiation xref: IntAct:EBI-541636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056007 ! ITPR1_HUMAN relationship: has_participant CCO:B0058502 ! TXND4_HUMAN [Term] id: CCO:I0015936 name: pex19-pex14-1 physical interaction comment: PEX19 binds multiple integral PMPs, as detected by far western blotting. xref: IntAct:EBI-594905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005820 ! PEX19_HUMAN relationship: has_participant CCO:B0054627 ! PEX14_HUMAN [Term] id: CCO:I0015937 name: csnk2a1-was-1 phosphorylation comment: in vitro phosphorylation of WASP by casein kinase II (CK2) xref: IntAct:EBI-603083 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005428 ! CSK21_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0015938 name: csnk2a1-was-2 phosphorylation comment: in vitro phosphorylation of WASP by casein kinase II (CK2) xref: IntAct:EBI-603094 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005428 ! CSK21_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0015939 name: cav2-cav1-1 physical interaction comment: Interaction between cav1 and flot 2 forming a cav1-cav2-flot1-flot2 heterooligomer xref: IntAct:EBI-603631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0005462 ! CAV2_HUMAN [Term] id: CCO:I0015940 name: flot1-cav1-1 physical interaction comment: Interaction between cav1 and flot 2 forming a cav1-cav2-flot1-flot2 heterooligomer xref: IntAct:EBI-603655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0062976 ! FLOT1_HUMAN [Term] id: CCO:I0015941 name: flot2-cav1-1 physical interaction comment: Interaction between cav1 and flot 2 forming a cav1-cav2-flot1-flot2 heterooligomer xref: IntAct:EBI-603661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0062977 ! FLOT2_HUMAN [Term] id: CCO:I0015942 name: epor-socs2-4 physical interaction comment: Interaction between human EpoR and SOCS2 demonstrated by MAPPIT xref: IntAct:EBI-617821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0015943 name: stk25-golga2-3 physical interaction comment: Interaction between YSK1 and GM130 identified by Y2H xref: IntAct:EBI-618343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN relationship: has_participant CCO:B0022748 ! STK25_HUMAN [Term] id: CCO:I0015944 name: mst4-golga2-1 physical interaction comment: Interaction between Mst4 and GM130 identified by Y2H xref: IntAct:EBI-618359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN relationship: has_participant CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:I0015945 name: btk-gtf21-2 physical interaction comment: Interaction between BTK and GTF21 (BAP135) identified by coimmunoprecipitation xref: IntAct:EBI-625110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0015946 name: btk-gtf21-3 physical interaction comment: Interaction between BTK and GTF21 (BAP135) identified by coimmunoprecipitation xref: IntAct:EBI-625147 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0015947 name: dyrk1b-map2k3-1 physical interaction comment: Interaction between DYRK1B and MAP2K3 identified by coimmunoprecipitation xref: IntAct:EBI-636006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020948 ! MP2K3_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0015948 name: skiip-ncor2-1 physical interaction comment: Interaction of SKIP and SMRT, detected by mammalian two hybrid. xref: IntAct:EBI-636316 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:I0015949 name: skiip-ncor2-2 physical interaction comment: Interaction of SKIP and SMRT, detected by mammalian two hybrid. xref: IntAct:EBI-636319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:I0015950 name: map4k2-mekk1-1 physical interaction comment: Human MAP4K2-MEKK1 co-immunoprecipitation xref: IntAct:EBI-636714 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005706 ! M4K2_HUMAN [Term] id: CCO:I0015951 name: erbb2-pik3c2b-2 direct interaction comment: Interaction of PIK3C2B and ERBB2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-641292 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN [Term] id: CCO:I0015952 name: hsp1-hsp4-11 physical interaction comment: Size-exclusion and IP: Co-elution of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0015953 name: hsp1-hsp4-12 physical interaction comment: Size-exclusion and IP: Co-elution of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0015954 name: wrn-wrn-1 physical interaction comment: Affinity chromatography: bait= WRN c-terminus , prey = WRN xref: IntAct:EBI-707434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN [Term] id: CCO:I0015955 name: wrn-g22p1-2 physical interaction comment: Affinity chromatography: bait= WRN c-terminus , prey = Ku86, ku70 xref: IntAct:EBI-707457 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0015956 name: wrn-fen1-1 physical interaction comment: Pull-down: bait = WRN, prey = FEN-1 xref: IntAct:EBI-707657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0015957 name: wrn-fen1-4 physical interaction comment: In vivo Co-IP: bait = WRN, prey = FEN-1 xref: IntAct:EBI-707699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0015958 name: atxn7-trrap-3 physical interaction comment: GST pulldown reveals interaction between Ataxin 7 protein and TRRAP, TAF10 the GCN5 protein xref: IntAct:EBI-708492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0015959 name: atxn7-trrap-4 physical interaction comment: GST pulldown reveals interaction between Ataxin 7 protein and TAF10 the GCN5 protein xref: IntAct:EBI-708503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0015960 name: app-apoa-5 physical interaction comment: Interaction of apoA-1 and amyloid beta detected by solid-phase ELISA assays. xref: IntAct:EBI-711042 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN [Term] id: CCO:I0015961 name: ptprn-ptprt-2 physical interaction comment: Y2H: bait = IA-2 intracellular domain, prey = PTP rho xref: IntAct:EBI-728280 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023006 ! PTPRT_HUMAN relationship: has_participant CCO:B0025847 ! PTPRN_HUMAN [Term] id: CCO:I0015962 name: rps6ka5-rela physical interaction comment: Interaction of Msk1 and the p65 RelA NF-kappaB subunit xref: IntAct:EBI-73901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0054653 ! KS6A5_HUMAN [Term] id: CCO:I0015963 name: nrbp-rac3-2 physical interaction comment: Interaction of NRBP with Rac3 identifed by coimmunoprecipitation xref: IntAct:EBI-767101 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025814 ! RAC3_HUMAN relationship: has_participant CCO:B0062919 ! NRBP_HUMAN [Term] id: CCO:I0015964 name: stk36-gli1-1 physical interaction comment: Interaction between STK36 (FUSED) and GLI1 identified by coimmunoprecipitation xref: IntAct:EBI-863822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005375 ! STK36_HUMAN relationship: has_participant CCO:B0054922 ! GLI1_HUMAN [Term] id: CCO:I0015965 name: stk36-gli3-1 physical interaction comment: Interaction between STK36 (FUSED) and GLI3 identified by coimmunoprecipitation xref: IntAct:EBI-863854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005375 ! STK36_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN [Term] id: CCO:I0015966 name: edf1-nr5a1-8 colocalization comment: Interaction between MBF1-alpha and Ad4BP detected by immunofluorescence staining xref: IntAct:EBI-874649 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0054582 ! EDF1_HUMAN relationship: has_participant CCO:B0055892 ! STF1_HUMAN [Term] id: CCO:I0015967 name: rgs19-gnai2-1 physical interaction comment: Weak interaction between GAIP and Gai2 detected by yeast two hybrid xref: IntAct:EBI-875225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0020776 ! RGS19_HUMAN [Term] id: CCO:I0015968 name: gemin5-eif4e-1 colocalization xref: IntAct:EBI-876970 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0062979 ! GEMI5_HUMAN [Term] id: CCO:I0015969 name: crebbp-nap1l1-2 direct interaction xref: IntAct:EBI-914436 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0015970 name: hbxap-smarca5-3 direct interaction xref: IntAct:EBI-926838 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:I0015971 name: mx1-trpc6-1 physical interaction comment: Y2H: bait = TRPC6 ARD domains, prey = MxA xref: IntAct:EBI-929361 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0062980 ! TRPC6_HUMAN [Term] id: CCO:I0015972 name: s100b-s100a11-1 physical interaction comment: Interaction between human S100B and S100A11 detected by Y2H xref: IntAct:EBI-945508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:I0015973 name: s100a1-s100b-1 physical interaction comment: Interaction between human S100A1 and S100B detected by Y2H xref: IntAct:EBI-945514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0015974 name: s100b-s100b-1 physical interaction comment: Homodimerisation of human S100B detected by Y2H xref: IntAct:EBI-945517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0015975 name: ifnar2-gnb2l1-4 physical interaction comment: Interaction of IFNAR2 and GNB2L1 identified by Y2H xref: IntAct:EBI-959607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0055406 ! INAR2_HUMAN [Term] id: CCO:I0015976 name: bcl2l11-ywhab-2 phosphorylation comment: Interaction between BCL2l11 (BIM(EL)) and YWHAB demonstrated by coimmunoprecipitation xref: IntAct:EBI-963245 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0006003 ! BIM_HUMAN [Term] id: CCO:I0015977 name: mpzl1-ptpn1 physical interaction xref: IntAct:EBI-963394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054748 ! MPZL1_HUMAN relationship: has_participant CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:I0015978 name: ptpn6-pilra-1 physical interaction xref: IntAct:EBI-965829 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0015779 ! PILRA_HUMAN [Term] id: CCO:I0015979 name: ptpn6-lair1-1 physical interaction xref: IntAct:EBI-965870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0062981 ! LAIR1_HUMAN [Term] id: CCO:I0015980 name: ptpn6-grb2-1 physical interaction xref: IntAct:EBI-965879 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005608 ! PTN6_HUMAN [Term] id: CCO:I0015981 name: ptpn6-sirpa-1 physical interaction xref: IntAct:EBI-965886 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0062831 ! SHPS1_HUMAN [Term] id: CCO:I0015982 name: src-actn1-1 physical interaction comment: Interaction between SRC and ACTN1 demonstrated by pulldown xref: IntAct:EBI-968854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0015983 name: birc2-traf2-5 physical interaction comment: Interaction between BIRC2 (cIAP1) and TRAF2 identified by coimmunoprecipitation xref: IntAct:EBI-977259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN [Term] id: CCO:I0015984 name: dicer1-tarbp2-1 physical interaction xref: IntAct:EBI-978601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0015985 name: adamts13-vwf-7 protein cleavage xref: IntAct:EBI-982617 is_a: CCO:Y0000039 ! protein cleavage relationship: has_participant CCO:B0031878 ! VWF_HUMAN relationship: has_participant CCO:B0057108 ! ATS13_HUMAN [Term] id: CCO:I0015986 name: foxp3-nfatc2 physical interaction xref: IntAct:EBI-983697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN [Term] id: CCO:I0015987 name: foxp2-nfatc2-1 physical interaction xref: IntAct:EBI-983778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015717 ! FOXP2_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:I0015988 name: foxp1-nfatc2 physical interaction xref: IntAct:EBI-983839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015712 ! FOXP1_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:I0015989 name: tbk1-birc4 phosphorylation xref: IntAct:EBI-988198 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0015990 name: arhgap24-flna-2 physical interaction comment: Interaction between ARHGAP24 and FLNA identified by pulldown xref: IntAct:EBI-988857 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0015991 name: mmp14-adi1-2 physical interaction xref: IntAct:EBI-992851 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032391 ! MTND_HUMAN relationship: has_participant CCO:B0055446 ! MMP14_HUMAN [Term] id: CCO:I0015992 name: st2-myd88-1 physical interaction xref: IntAct:EBI-997149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055691 ! ILRL1_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0015993 name: st2-traf6-1 physical interaction xref: IntAct:EBI-997176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0055691 ! ILRL1_HUMAN [Term] id: CCO:I0015994 name: st2-irak4-1 physical interaction xref: IntAct:EBI-997187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055691 ! ILRL1_HUMAN relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN [Term] id: CCO:I0015995 name: nphs1-nck2 physical interaction comment: Pulldown analysis reveals interaction between Nephrin protein and Nck2 protein xref: IntAct:EBI-997558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0062983 ! NPHN_HUMAN [Term] id: CCO:I0015996 name: nphs1-nck2-1 colocalization comment: Colocalisation analysis reveals interaction between Nephrin protein and Nck2 protein xref: IntAct:EBI-997778 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0062983 ! NPHN_HUMAN [Term] id: CCO:I0015997 name: pscdbp-pscd1-1 physical interaction xref: IntAct:EBI-997826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054577 ! CYTIP_HUMAN relationship: has_participant CCO:B0056063 ! CYH1_HUMAN [Term] id: CCO:I0015998 name: pscd1-pscdbp-1 physical interaction xref: IntAct:EBI-997880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054577 ! CYTIP_HUMAN relationship: has_participant CCO:B0056063 ! CYH1_HUMAN [Term] id: CCO:I0015999 name: stk4-sav1-2 physical interaction comment: Interaction betweenSTK4 (MST1) and STV1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1017793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005702 ! STK4_HUMAN relationship: has_participant CCO:B0058715 ! SAV1_HUMAN [Term] id: CCO:I0016000 name: stk3-sav1-1 physical interaction comment: Interaction betweenSTK3 (MST2) and STV1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1017808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055885 ! STK3_HUMAN relationship: has_participant CCO:B0058715 ! SAV1_HUMAN [Term] id: CCO:I0016001 name: stk4-sav1-3 physical interaction comment: Interaction betweenSTK4 (MST1) and STV1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1025056 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005702 ! STK4_HUMAN relationship: has_participant CCO:B0058715 ! SAV1_HUMAN [Term] id: CCO:I0016002 name: stk3-sav1-2 physical interaction comment: Interaction betweenSTK3 (MST2) and STV1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1025177 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055885 ! STK3_HUMAN relationship: has_participant CCO:B0058715 ! SAV1_HUMAN [Term] id: CCO:I0016003 name: sav1-sav1-1 physical interaction comment: Homodimerization of SAV1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1025216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058715 ! SAV1_HUMAN [Term] id: CCO:I0016004 name: arhgdia-rac1-1 direct interaction comment: Rac1-rhogdi complex involved in nadph oxidase activation xref: IntAct:EBI-1031753 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN [Term] id: CCO:I0016005 name: s100a1-s100p-3 direct interaction xref: IntAct:EBI-1110996 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055155 ! S10A1_HUMAN relationship: has_participant CCO:B0062804 ! S100P_HUMAN [Term] id: CCO:I0016006 name: myh9-s100p direct interaction xref: IntAct:EBI-1149105 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0062804 ! S100P_HUMAN [Term] id: CCO:I0016007 name: cftr-ebp-3 physical interaction xref: IntAct:EBI-1171876 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0016220 ! DNJB1_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN relationship: has_participant CCO:B0027148 ! S61A2_HUMAN relationship: has_participant CCO:B0027154 ! S61A1_HUMAN relationship: has_participant CCO:B0051700 ! S10A7_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0062984 ! LEG4_HUMAN relationship: has_participant CCO:B0062985 ! PIMT_HUMAN relationship: has_participant CCO:B0062986 ! VPS4A_HUMAN relationship: has_participant CCO:B0062987 ! F120A_HUMAN relationship: has_participant CCO:B0062988 ! COPB_HUMAN relationship: has_participant CCO:B0062989 ! LMNA_HUMAN relationship: has_participant CCO:B0062990 ! SFXN3_HUMAN relationship: has_participant CCO:B0062991 ! FAT1_HUMAN relationship: has_participant CCO:B0062992 ! TRIPC_HUMAN [Term] id: CCO:I0016008 name: fyn-htr6-4 physical interaction comment: Interaction between HTR6 and FYN identified by coimmunoprecipitation xref: IntAct:EBI-1182277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:I0016009 name: abcb1-rnf2 physical interaction comment: P-glycoprotein interacts with RNF2 in a yeast two-hybrid assay xref: IntAct:EBI-1198183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020552 ! RING2_HUMAN relationship: has_participant CCO:B0062993 ! MDR1_HUMAN [Term] id: CCO:I0016010 name: map4k5-crk-1 physical interaction comment: MAP4K5 -Crk identified by GST pull-down xref: IntAct:EBI-1284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:I0016011 name: map4k5-crkl-1 physical interaction comment: MAP4K5 -CrkL identified by GST xref: IntAct:EBI-1290 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:I0016012 name: itgav-angptl3-1 physical interaction comment: ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo. xref: IntAct:EBI-298293 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026218 ! ITAV_HUMAN relationship: has_participant CCO:B0059377 ! ANGL3_HUMAN [Term] id: CCO:I0016013 name: il6r-arts1 physical interaction comment: An aminopeptidase, ARTS-1 interacts with ectodomain of IL-6 receptor alpha, promoting interleukin-6 receptor shedding. xref: IntAct:EBI-299444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054933 ! IL6RA_HUMAN relationship: has_participant CCO:B0062994 ! ERAP1_HUMAN [Term] id: CCO:I0016014 name: nfkb1-pdcd11-2 physical interaction comment: Interaction of NFKB1 with PDCD11 confirmed by GST-pull down. xref: IntAct:EBI-300045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0062995 ! RRP5_HUMAN [Term] id: CCO:I0016015 name: rela-pdcd11-1 physical interaction comment: Interaction of RELA with PDCD11 confirmed by GST-pull down. xref: IntAct:EBI-300049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0062995 ! RRP5_HUMAN [Term] id: CCO:I0016016 name: orc6l-orc4l direct interaction xref: IntAct:EBI-375143 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005388 ! ORC6_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN [Term] id: CCO:I0016017 name: orc3l-orc5l direct interaction xref: IntAct:EBI-375149 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005390 ! ORC5_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0016018 name: orc6l-mcm4 direct interaction xref: IntAct:EBI-375152 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005388 ! ORC6_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN [Term] id: CCO:I0016019 name: orc1l-orc5l direct interaction xref: IntAct:EBI-375182 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005352 ! ORC1_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0016020 name: orc1l-orc2l direct interaction xref: IntAct:EBI-375185 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005352 ! ORC1_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN [Term] id: CCO:I0016021 name: orc6l-orc3l direct interaction xref: IntAct:EBI-375239 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005388 ! ORC6_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0016022 name: orc5l-orc4l direct interaction xref: IntAct:EBI-375257 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005389 ! ORC4_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0016023 name: orc1l-orc3l direct interaction xref: IntAct:EBI-375260 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005352 ! ORC1_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0016024 name: orc4l-orc3l direct interaction xref: IntAct:EBI-375284 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005389 ! ORC4_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN [Term] id: CCO:I0016025 name: orc2l-orc5l direct interaction xref: IntAct:EBI-375290 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005353 ! ORC2_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0016026 name: orc5l-orc5l direct interaction xref: IntAct:EBI-375308 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005390 ! ORC5_HUMAN [Term] id: CCO:I0016027 name: orc2l-orc4l direct interaction xref: IntAct:EBI-375389 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005353 ! ORC2_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN [Term] id: CCO:I0016028 name: rn11-amsh-2 physical interaction comment: Interaction beween RNF11 and AMSH confirmed by co-immunoprecipitation xref: IntAct:EBI-396723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0062996 ! RNF11_HUMAN [Term] id: CCO:I0016029 name: rn11-amsh-3 physical interaction comment: RNF11 and AMSH interact with Smurf2 demonstrated by co-immunoprecipitation xref: IntAct:EBI-396743 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0058768 ! SMUF2_HUMAN relationship: has_participant CCO:B0062996 ! RNF11_HUMAN [Term] id: CCO:I0016030 name: rn11-suf2-1 physical interaction comment: Interaction between RAF11 and SMURF2 demonstrated by co-immunoprecipitation xref: IntAct:EBI-396751 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058768 ! SMUF2_HUMAN relationship: has_participant CCO:B0062996 ! RNF11_HUMAN [Term] id: CCO:I0016031 name: ixl-usp49-3 physical interaction comment: Interaction detected by comigration on DEAE Column.. xref: IntAct:EBI-399759 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN [Term] id: CCO:I0016032 name: q9nwa0-vdrip-4 physical interaction comment: Interaction detected by GST pulldown. xref: IntAct:EBI-400057 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN [Term] id: CCO:I0016033 name: q9nwa0-vdrip-5 physical interaction comment: Interaction detected by GST pulldown. xref: IntAct:EBI-400062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN [Term] id: CCO:I0016034 name: tcerg1-luc7l physical interaction xref: IntAct:EBI-474291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN relationship: has_participant CCO:B0025768 ! LUC7L_HUMAN [Term] id: CCO:I0016035 name: pias4-tcerg1 physical interaction comment: Y2H: CA150 (TCERG1) and PIASy xref: IntAct:EBI-474298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0016036 name: cltc-g22p1 physical interaction xref: IntAct:EBI-474312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016037 name: hd-crmp1 physical interaction xref: IntAct:EBI-474326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0016038 name: gadd45g-eef1a1 physical interaction xref: IntAct:EBI-474340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0016039 name: gadd45g-eef1g physical interaction xref: IntAct:EBI-474354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0016040 name: gadd45g-dkfzp564o052 physical interaction xref: IntAct:EBI-474396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0062998 ! Q9H0V7_HUMAN [Term] id: CCO:I0016041 name: gadd45g-kiaa1377-1 physical interaction xref: IntAct:EBI-474403 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN [Term] id: CCO:I0016042 name: gadd45g-luc7l physical interaction xref: IntAct:EBI-474410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0025768 ! LUC7L_HUMAN [Term] id: CCO:I0016043 name: gadd45g-pias4 physical interaction xref: IntAct:EBI-474424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN [Term] id: CCO:I0016044 name: gadd45g-ok/sw_cl_16 physical interaction xref: IntAct:EBI-474431 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005408 ! Q8NI70_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN [Term] id: CCO:I0016045 name: gadd45g-soh1 physical interaction xref: IntAct:EBI-474438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0016046 name: gadd45g-luc7l2 physical interaction xref: IntAct:EBI-474445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:I0016047 name: gapd-htatip physical interaction xref: IntAct:EBI-474452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:I0016048 name: gadd45g-gdf9 physical interaction xref: IntAct:EBI-474459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0016049 name: ok/sw_cl_16-git1 physical interaction xref: IntAct:EBI-474473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005408 ! Q8NI70_HUMAN [Term] id: CCO:I0016050 name: kiaa1377-git1-1 physical interaction xref: IntAct:EBI-474480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0016051 name: kiaa1377-hbo1-1 physical interaction xref: IntAct:EBI-474522 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0016052 name: gadd45g-utp14a-1 physical interaction xref: IntAct:EBI-474550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0016053 name: hip2-pias4 physical interaction xref: IntAct:EBI-474557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0050171 ! UBE2K_HUMAN [Term] id: CCO:I0016054 name: immt-pias4 physical interaction comment: Y2H: HMP (Mitofilin) and PIASy xref: IntAct:EBI-474585 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:I0016055 name: hd-fnbp3 physical interaction xref: IntAct:EBI-474613 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:I0016056 name: hd-fnbp3-1 physical interaction xref: IntAct:EBI-474620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:I0016057 name: hd-fnbp3-2 physical interaction xref: IntAct:EBI-474627 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:I0016058 name: hd-hip1 physical interaction xref: IntAct:EBI-474634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006214 ! HIP1_HUMAN [Term] id: CCO:I0016059 name: hd-sh3gl3 physical interaction xref: IntAct:EBI-474641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0016060 name: hd-sh3gl3-1 physical interaction xref: IntAct:EBI-474648 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0016061 name: hd-sh3gl3-2 physical interaction xref: IntAct:EBI-474655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0016062 name: hd-gprasp2 physical interaction xref: IntAct:EBI-474662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005405 ! GASP2_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016063 name: hd-gprasp2-1 physical interaction xref: IntAct:EBI-474669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005405 ! GASP2_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016064 name: hd-pias4 physical interaction xref: IntAct:EBI-474676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016065 name: hd-pias4-1 physical interaction xref: IntAct:EBI-474683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016066 name: hd-soh1 physical interaction xref: IntAct:EBI-474690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0016067 name: hd-soh1-1 physical interaction xref: IntAct:EBI-474697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0016068 name: hd-soh1-2 physical interaction xref: IntAct:EBI-474704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0016069 name: hd-git1 physical interaction xref: IntAct:EBI-474711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016070 name: hd-git1-8 physical interaction xref: IntAct:EBI-474718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016071 name: hd-kiaa1377 physical interaction xref: IntAct:EBI-474725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016072 name: hd-utp14a physical interaction xref: IntAct:EBI-474732 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0016073 name: hd-fez1 physical interaction xref: IntAct:EBI-474760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016074 name: hd-fez1-1 physical interaction xref: IntAct:EBI-474767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016075 name: hd-ikbkap physical interaction xref: IntAct:EBI-474774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016076 name: hd-ikbkap-1 physical interaction xref: IntAct:EBI-474781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016077 name: hd-ikbkap-2 physical interaction xref: IntAct:EBI-474788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016078 name: hd-pfn2 physical interaction xref: IntAct:EBI-474809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0016079 name: hd-pfn2-1 physical interaction xref: IntAct:EBI-474816 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0016080 name: hd-pfn2-2 physical interaction xref: IntAct:EBI-474823 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0016081 name: hd-tcerg1 physical interaction xref: IntAct:EBI-474830 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016082 name: hd-tcerg1-1 physical interaction xref: IntAct:EBI-474837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016083 name: hd-tcerg1-2 physical interaction xref: IntAct:EBI-474844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016084 name: impdh2-pias4 physical interaction xref: IntAct:EBI-474977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0054998 ! IMDH2_HUMAN [Term] id: CCO:I0016085 name: kpnb1-pias4 physical interaction xref: IntAct:EBI-475005 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005409 ! IMB1_HUMAN [Term] id: CCO:I0016086 name: cct3-g22p1 physical interaction xref: IntAct:EBI-475026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0016087 name: hd-g22p1 physical interaction xref: IntAct:EBI-475033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0016088 name: hd-g22p1-1 physical interaction xref: IntAct:EBI-475040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0016089 name: mageh1-pias4 physical interaction comment: Y2H: PIASy and MAGEH1 xref: IntAct:EBI-475047 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005406 ! MAGH1_HUMAN [Term] id: CCO:I0016090 name: kiaa1377-bp465 physical interaction xref: IntAct:EBI-475054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005400 ! BRD7_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0016091 name: fnbp3-pias4 physical interaction comment: Y2H: FNBP3 (HYPA) and PIASy xref: IntAct:EBI-475103 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:I0016092 name: gadd45g-htatip-1 physical interaction xref: IntAct:EBI-475110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN [Term] id: CCO:I0016093 name: kiaa1377-htatip-1 physical interaction xref: IntAct:EBI-475124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0016094 name: gadd45g-ptprk physical interaction xref: IntAct:EBI-475166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0022999 ! PTPRK_HUMAN [Term] id: CCO:I0016095 name: tcerg1-setdb1 physical interaction comment: Y2H: SETD1 and TCERG1 (CA150) xref: IntAct:EBI-475173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0016096 name: vim-sh3gl3 physical interaction xref: IntAct:EBI-475187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0016097 name: ok/sw_cl_16-sh3gl3 physical interaction xref: IntAct:EBI-475194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005408 ! Q8NI70_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0016098 name: pias4-smt3h1 physical interaction xref: IntAct:EBI-475201 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0063000 ! SUMO3_HUMAN [Term] id: CCO:I0016099 name: pias4-smt3h2 physical interaction comment: Y2H: PIASy and SUMO3 xref: IntAct:EBI-475208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0016100 name: smt3h2-setdb1 physical interaction comment: Y2H: SUMO3 and SETDB1 xref: IntAct:EBI-475215 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0016101 name: taldo1-zhx1 physical interaction xref: IntAct:EBI-475222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0020161 ! TALDO_HUMAN [Term] id: CCO:I0016102 name: vim-setdb1 physical interaction comment: Y2H: vimentin and SETDB1 xref: IntAct:EBI-475264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016103 name: vim-hbo1 physical interaction xref: IntAct:EBI-475278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016104 name: vim-zhx1 physical interaction xref: IntAct:EBI-475285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016105 name: vim-pias4 physical interaction xref: IntAct:EBI-475299 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016106 name: fnbp3-zhx1 physical interaction xref: IntAct:EBI-475334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:I0016107 name: pias4-zhx1 physical interaction xref: IntAct:EBI-475341 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN [Term] id: CCO:I0016108 name: map4k5-grb2-1 physical interaction comment: MAP4K5 -GRB2 identified by GST xref: IntAct:EBI-492201 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:I0016109 name: syk-fcer1g-1 physical interaction comment: GST-pull down : bait = tandem SH2 domains of syk; prey= FcR gamma chain xref: IntAct:EBI-515302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055217 ! FCERG_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:I0016110 name: g22p1-xrcc5-1 direct interaction comment: Interaction of Ku70 and Ku86 demonstrated by X-ray crystallography xref: IntAct:EBI-516722 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0016111 name: g22p1-xrcc5-2 direct interaction comment: Interaction of Ku70 and Ku86 demonstrated by X-ray crystallography xref: IntAct:EBI-516732 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0016112 name: fadd-mbd4 physical interaction comment: The FADD protein interacts with the Methyl CpG binding protein 4 xref: IntAct:EBI-517960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0063002 ! MBD4_HUMAN [Term] id: CCO:I0016113 name: fadd-myd88 physical interaction comment: The FADD protein interacts with the myeloid differentiation primary response protein MyD88 xref: IntAct:EBI-518940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0016114 name: fadd-myd88-1 physical interaction comment: The FADD protein death domain interacts with the myeloid differentiation primary response protein MyD88 death domain xref: IntAct:EBI-518976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0016115 name: hvem-light physical interaction comment: FACS analysis reveals the interaction of the tumor necrosis factor receptor superfamily member 14 precursor protein (HVEM) and the Tumor necrosis factor ligand superfamily member 14 protein (LIGHT) xref: IntAct:EBI-524125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0054490 ! TNF14_HUMAN [Term] id: CCO:I0016116 name: traf6-tab1-1 physical interaction comment: Coimmunoprecipitation reveals interaction between TNF receptor associated factor 6 (TRAF6), TAK1 protein and TAB1 protein xref: IntAct:EBI-526152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:I0016117 name: ikk-nik physical interaction comment: Coimmunoprecipitation reveals interaction between the Inhibitor of nuclear factor kappa-B kinase alpha subunit , TAK1 and NIK proteins xref: IntAct:EBI-526235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:I0016118 name: tak1-ikap physical interaction comment: Coimmunoprecipitation reveals interaction between mitogen-activated protein kinase kinase kinase 7 (TAK1) protein and the IkappaB kinase complex-associated protein xref: IntAct:EBI-526254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:I0016119 name: pias4-smt3h2-1 physical interaction comment: Y2H: PIASy and SUMO3 xref: IntAct:EBI-532097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0016120 name: sfpq-ptbp1-1 physical interaction xref: IntAct:EBI-591289 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0037269 ! PTBP1_HUMAN [Term] id: CCO:I0016121 name: snrpa-sfpq-1 physical interaction xref: IntAct:EBI-607092 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0063003 ! SNRPA_HUMAN [Term] id: CCO:I0016122 name: sap18-hdac1-2 physical interaction comment: Co-ip (in-vivo) showing interaction between sap18 and hdac1. xref: IntAct:EBI-621012 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0006113 ! SAP18_HUMAN [Term] id: CCO:I0016123 name: dyrk1b-ranbp9-3 physical interaction comment: Interaction between DYRK1B and RANBP9 identified by coimmunoprecipitation xref: IntAct:EBI-636128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN relationship: has_participant CCO:B0063004 ! RANB9_HUMAN [Term] id: CCO:I0016124 name: app-apoa1-1 physical interaction comment: Interaction of Amyloid Precursor Protein with Apolipoprotein A-1 detected by yeast two hybrid. xref: IntAct:EBI-701702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN [Term] id: CCO:I0016125 name: btk-prkcq-2 physical interaction comment: Interaction between BTK and PRKCQ (PKC-theta) demonstrated by GST pulldown xref: IntAct:EBI-704304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0016126 name: hsp1-hsp4-1 physical interaction comment: CoIP: bait = HPS4, prey=HA-HPS1 xref: IntAct:EBI-704408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0016127 name: hsp1-hsp4-2 physical interaction comment: CoIP: bait = HPS1, prey=myc-HPS4 xref: IntAct:EBI-704415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0016128 name: hsp1-hsp4-14 physical interaction comment: Co-sedimentation of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0016129 name: atxn7-trrap-6 physical interaction comment: Coimmunoprecipitation reveals interaction between Ataxin 7 protein and TRRAP protein xref: IntAct:EBI-708546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0016130 name: trrap-1-atxn7-1 physical interaction comment: Coimmunoprecipitation reveals interaction between TRRAPprotein and Ataxin 7 protein xref: IntAct:EBI-708555 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0016131 name: eif4e-mnk1 physical interaction comment: Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E xref: IntAct:EBI-73920 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:I0016132 name: mnk1-eif4e physical interaction comment: Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E xref: IntAct:EBI-73979 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:I0016133 name: eif4g-mnk1 physical interaction comment: Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E xref: IntAct:EBI-73986 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:I0016134 name: mnk1-eif4g physical interaction comment: Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E xref: IntAct:EBI-74022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0058519 ! MKNK1_HUMAN [Term] id: CCO:I0016135 name: gan-map1b physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the Gigaxonin protein and MAP1B protein xref: IntAct:EBI-764620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055380 ! MAP1B_HUMAN relationship: has_participant CCO:B0063005 ! GAN_HUMAN [Term] id: CCO:I0016136 name: plzf-pml-3 direct interaction comment: Interaction between PLZF and PML detected by pulldown xref: IntAct:EBI-779748 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0016137 name: plzf-pml-4 direct interaction comment: Interaction between PLZF and PML detected by pulldown xref: IntAct:EBI-779755 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0016138 name: plzf-plzf-1 direct interaction comment: PLZF homodimerisation detected by pulldown xref: IntAct:EBI-779762 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0016139 name: dnmt3b-ubl1-2 physical interaction xref: IntAct:EBI-80231 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:I0016140 name: xrcc4-aprataxin-1 physical interaction comment: Interaction between human XRCC4 and Aprataxin detected by Y2H xref: IntAct:EBI-847883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005651 ! XRCC4_HUMAN relationship: has_participant CCO:B0005943 ! APTX_HUMAN [Term] id: CCO:I0016141 name: map4k1-crk-2 physical interaction comment: MAP4K1 -Crk identified by GST xref: IntAct:EBI-895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:I0016142 name: hdac1-nfkb1-7 direct interaction xref: IntAct:EBI-904553 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0016143 name: hdac1-rela direct interaction xref: IntAct:EBI-904570 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0016144 name: hdac1-nfkb1-8 direct interaction xref: IntAct:EBI-904580 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0016145 name: hdac1-rela-4 direct interaction xref: IntAct:EBI-904590 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0016146 name: lrp6-tem8 physical interaction xref: IntAct:EBI-910929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025967 ! LRP6_HUMAN relationship: has_participant CCO:B0063006 ! ANTR1_HUMAN [Term] id: CCO:I0016147 name: lrp6-tem8-1 physical interaction xref: IntAct:EBI-910937 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025967 ! LRP6_HUMAN relationship: has_participant CCO:B0063006 ! ANTR1_HUMAN [Term] id: CCO:I0016148 name: lrp6-tem8-2 physical interaction xref: IntAct:EBI-910944 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025967 ! LRP6_HUMAN relationship: has_participant CCO:B0063006 ! ANTR1_HUMAN [Term] id: CCO:I0016149 name: lrp6-cmg2 physical interaction xref: IntAct:EBI-910962 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025967 ! LRP6_HUMAN relationship: has_participant CCO:B0063007 ! ANTR2_HUMAN [Term] id: CCO:I0016150 name: map4k1-crkl-4 physical interaction comment: MAP4K1 -CrkL identified by GST xref: IntAct:EBI-921 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:I0016151 name: nck1-waspip-3 physical interaction comment: GST Pull-down: bait= human Nck, prey = human WIP xref: IntAct:EBI-921702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0063008 ! WIPF1_HUMAN [Term] id: CCO:I0016152 name: baz1b-myo1c physical interaction xref: IntAct:EBI-935096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027842 ! MYH1_HUMAN relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0016153 name: eif4e-4ebp1-1 direct interaction comment: Interaction between eIF4E and 4E-BP1 demonstrated by Far Western xref: IntAct:EBI-935103 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:I0016154 name: baz1b-smrca5 physical interaction xref: IntAct:EBI-935118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0016155 name: eif4e-4ebp2-1 direct interaction comment: Interaction between eIF4E and 4E-BP2 demonstrated by Far Western xref: IntAct:EBI-935146 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055928 ! 4EBP2_HUMAN [Term] id: CCO:I0016156 name: eif4e-4ebp3-1 direct interaction comment: Interaction between eIF4E and 4E-BP3 demonstrated by Far Western xref: IntAct:EBI-935156 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0054565 ! 4EBP3_HUMAN [Term] id: CCO:I0016157 name: mllt6-ubqln4 physical interaction xref: IntAct:EBI-946304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0042847 ! AF17_HUMAN [Term] id: CCO:I0016158 name: ubqln4-znf205 physical interaction xref: IntAct:EBI-946325 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0054735 ! ZN205_HUMAN [Term] id: CCO:I0016159 name: a2bp1-numbl physical interaction xref: IntAct:EBI-946339 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059414 ! NUMBL_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0016160 name: pdcd8-tsc22d4 physical interaction xref: IntAct:EBI-946353 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0016161 name: atn1-trip6 physical interaction xref: IntAct:EBI-946367 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:I0016162 name: atxn1-cpsf5 physical interaction xref: IntAct:EBI-946381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062837 ! CPSF5_HUMAN [Term] id: CCO:I0016163 name: atxn1-crk physical interaction xref: IntAct:EBI-946388 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:I0016164 name: atxn1-dazap2 physical interaction xref: IntAct:EBI-946395 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0016165 name: atxn1-flj12529 physical interaction xref: IntAct:EBI-946402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:I0016166 name: atxn1-kiaa0174 physical interaction xref: IntAct:EBI-946409 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0026635 ! K0174_HUMAN [Term] id: CCO:I0016167 name: atxn1-klhl12 physical interaction xref: IntAct:EBI-946416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0056358 ! KLH12_HUMAN [Term] id: CCO:I0016168 name: atxn1-c1orf94 physical interaction xref: IntAct:EBI-946423 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063009 ! CA094_HUMAN [Term] id: CCO:I0016169 name: atxn1-plekha5 physical interaction xref: IntAct:EBI-946430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:I0016170 name: atxn1-rbm9 physical interaction xref: IntAct:EBI-946437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0016171 name: atxn1-rbpms physical interaction xref: IntAct:EBI-946444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0016172 name: atxn1-tbc1d5 physical interaction xref: IntAct:EBI-946451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:I0016173 name: atxn1-traf2 physical interaction xref: IntAct:EBI-946458 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0016174 name: atxn1-trim32 physical interaction xref: IntAct:EBI-946465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062794 ! TRI32_HUMAN [Term] id: CCO:I0016175 name: atxn1-u2af2 physical interaction xref: IntAct:EBI-946472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:I0016176 name: nr0b1-rora physical interaction xref: IntAct:EBI-946535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0055483 ! NR0B1_HUMAN [Term] id: CCO:I0016177 name: a2bp1-atxn1 physical interaction xref: IntAct:EBI-946556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0016178 name: a2bp1-rbm9 physical interaction xref: IntAct:EBI-946570 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054463 ! RBM9_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0016179 name: atxn1-bat2 physical interaction xref: IntAct:EBI-946577 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:I0016180 name: atxn1-cfl1 physical interaction xref: IntAct:EBI-946584 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0016181 name: atxn1-hivep1 physical interaction xref: IntAct:EBI-946591 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0016182 name: atxn1-yy1ap1 physical interaction xref: IntAct:EBI-946598 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063012 ! YYAP1_HUMAN [Term] id: CCO:I0016183 name: atxn1-zhx1 physical interaction xref: IntAct:EBI-946605 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0016184 name: atxn1-atxn2 physical interaction xref: IntAct:EBI-946612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0016185 name: atxn1-six5 physical interaction xref: IntAct:EBI-946619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057426 ! SIX5_HUMAN [Term] id: CCO:I0016186 name: atxn1-derp6 physical interaction xref: IntAct:EBI-946633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057948 ! DERP6_HUMAN [Term] id: CCO:I0016187 name: cenpj-cic physical interaction xref: IntAct:EBI-946640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005426 ! CENPJ_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0016188 name: pcbp1-tsc22d4 physical interaction xref: IntAct:EBI-946675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:I0016189 name: atxn1-rbpms-2 physical interaction xref: IntAct:EBI-957335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0016190 name: atxn1-rbpms-3 physical interaction xref: IntAct:EBI-957350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0016191 name: gch1-aha1-2 physical interaction comment: GST pulldown analysis reveals interaction between GCH1 protein and Aha1protein xref: IntAct:EBI-958359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0063014 ! AHSA1_HUMAN [Term] id: CCO:I0016192 name: s100b-s100b-4 physical interaction comment: Homodimerisation of human S100B detected by coIP xref: IntAct:EBI-959891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0016193 name: s100b-s100a11-3 physical interaction comment: Interaction between human S100B and S100A11 detected by coIP xref: IntAct:EBI-959899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:I0016194 name: s100b-s100a1-1 physical interaction comment: Interaction between human S100B and S100A1 detected by coIP xref: IntAct:EBI-959906 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0016195 name: hsf1-mk2-2 phosphorylation xref: IntAct:EBI-993415 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0026467 ! HSF1_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:I0016196 name: tmed10-psen1-4 physical interaction xref: IntAct:EBI-998810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0038128 ! TMED2_HUMAN relationship: has_participant CCO:B0058062 ! NICA_HUMAN relationship: has_participant CCO:B0058989 ! PEN2_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0016197 name: cga-fshb-1 direct interaction comment: Human follicle stimulating hormone xref: IntAct:EBI-1030667 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006263 ! GLHA_HUMAN relationship: has_participant CCO:B0054839 ! FSHB_HUMAN [Term] id: CCO:I0016198 name: hba1-hbb-16 direct interaction comment: Crystal structure of deoxy hbalphayq, a mutant of hba xref: IntAct:EBI-1032478 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0016199 name: hba1-hbb-17 direct interaction comment: Crystal structure of deoxy hbbetayq, a site directed mutant of hba xref: IntAct:EBI-1032489 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0016200 name: ncbp1-ncbp2-1 direct interaction comment: Structure of the human nuclear cap-binding-complex (cbc) in complex with a cap analogue m7gpppg xref: IntAct:EBI-1034563 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN relationship: has_participant CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:I0016201 name: ncbp1-ncbp2-2 direct interaction comment: Structure of the human nuclear cap-binding-complex (cbc) in complex with a cap analogue m7gpppg xref: IntAct:EBI-1034574 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN relationship: has_participant CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:I0016202 name: ncbp1-ncbp2-3 direct interaction comment: Structure of the human nuclear cap-binding-complex (cbc) xref: IntAct:EBI-1034585 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN relationship: has_participant CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:I0016203 name: itgav-itgb3-3 direct interaction comment: A novel adaptation of the integrin psi domain revealed from its crystal structure xref: IntAct:EBI-1039821 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026218 ! ITAV_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0016204 name: esr1-foxo1a physical interaction xref: IntAct:EBI-1108800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:I0016205 name: cxcr4-myh9-2 physical interaction comment: Interaction between human CXCR4 and MYH9 detected by pulldown xref: IntAct:EBI-1127489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:I0016206 name: cxcr4-myh9-4 physical interaction comment: Interaction between human CXCR4 and MYH9 detected by coIP xref: IntAct:EBI-1128536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:I0016207 name: map2k2-araf-1 physical interaction comment: Interaction between MAP2K2 and ARAF identified by Y2H xref: IntAct:EBI-1164984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:I0016208 name: map2k2-raf1-1 physical interaction comment: Interaction between MAP2K2 and RAF1 identified by Y2H xref: IntAct:EBI-1164988 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:I0016209 name: map2k2-mapk2-1 physical interaction comment: Homodimerisation of MAP2K2 identified by Y2H xref: IntAct:EBI-1164995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:I0016210 name: map2k2-ksr-1 physical interaction comment: Interaction between KSR and MAP2K2 identified by Y2H xref: IntAct:EBI-1165002 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN relationship: has_participant CCO:B0057348 ! KSR1_HUMAN [Term] id: CCO:I0016211 name: h3_peptide-fbxl11 direct interaction xref: IntAct:EBI-1172996 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006051 ! JHD1A_HUMAN relationship: has_participant CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:I0016212 name: morf4l2-cdr2-3 direct interaction comment: PCD17 coimmunoprecipitates with MRG X xref: IntAct:EBI-1181611 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0063018 ! CDR2_HUMAN [Term] id: CCO:I0016213 name: fyn-htr6-7 physical interaction comment: Interaction between HTR6 and FYN identified by coimmunoprecipitation xref: IntAct:EBI-1182315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:I0016214 name: csnk1e-per2 phosphorylation comment: CKI epsilon phosphorylates PER2 peptide (phosphorylated at S662) in an in vitro phosphorylation assay xref: IntAct:EBI-1187581 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005272 ! KC1E_HUMAN relationship: has_participant CCO:B0054400 ! PER2_HUMAN [Term] id: CCO:I0016215 name: nup107-nup160-1 physical interaction comment: Interactions within the complex detected by CoIP. xref: IntAct:EBI-295747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055505 ! NUP98_HUMAN relationship: has_participant CCO:B0063020 ! NU107_HUMAN [Term] id: CCO:I0016216 name: nup133-nup160-1 physical interaction comment: Interactions within complex determined by CoIP. xref: IntAct:EBI-295755 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055505 ! NUP98_HUMAN relationship: has_participant CCO:B0063021 ! NU133_HUMAN [Term] id: CCO:I0016217 name: itgb2-syk physical interaction comment: Interaction between ITGB2 and SYK detected by CoIP. xref: IntAct:EBI-300190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033122 ! ITB2_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:I0016218 name: hck-elmo1-1 physical interaction comment: Interaction between HCK and ELMO1 detected by GST pull down xref: IntAct:EBI-346444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0016219 name: brap-hras-3 physical interaction comment: Interaction between H-Ras and BRAP confirmed in vivo xref: IntAct:EBI-350185 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005471 ! BRAP_HUMAN [Term] id: CCO:I0016220 name: app-apb1-1 physical interaction comment: APP-X11 in vivo interaction. xref: IntAct:EBI-371396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063022 ! APBA1_HUMAN [Term] id: CCO:I0016221 name: il7-il7r-3 physical interaction xref: IntAct:EBI-371594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0055060 ! IL7RA_HUMAN [Term] id: CCO:I0016222 name: cog4-cog7-1 physical interaction comment: The binary interacting network of the conserved oligomeric Golgi tethering complex xref: IntAct:EBI-389549 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055660 ! COG7_HUMAN relationship: has_participant CCO:B0063023 ! COG4_HUMAN [Term] id: CCO:I0016223 name: cog7-cog4-1 physical interaction comment: The binary interacting network of the conserved oligomeric Golgi tethering complex xref: IntAct:EBI-389561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055660 ! COG7_HUMAN relationship: has_participant CCO:B0063023 ! COG4_HUMAN [Term] id: CCO:I0016224 name: cog5-cog7-1 physical interaction comment: The binary interacting network of the conserved oligomeric Golgi tethering complex xref: IntAct:EBI-389594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055660 ! COG7_HUMAN relationship: has_participant CCO:B0063024 ! COG5_HUMAN [Term] id: CCO:I0016225 name: cog7-cog5-1 physical interaction comment: The binary interacting network of the conserved oligomeric Golgi tethering complex xref: IntAct:EBI-389601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055660 ! COG7_HUMAN relationship: has_participant CCO:B0063024 ! COG5_HUMAN [Term] id: CCO:I0016226 name: abi1-ncf1-2 physical interaction comment: GST pull down : ncf1 and p47 phox xref: IntAct:EBI-395069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:I0016227 name: tceb1-tceb2-1 physical interaction comment: Interaction of Med8 with EloB and EloC. xref: IntAct:EBI-398510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0016228 name: tceb1-tceb2-2 physical interaction comment: Interaction of Med8 with EloB and EloC. xref: IntAct:EBI-398517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0016229 name: rab5-eea1-1 physical interaction comment: Interaction between EEA1 and Rab2 detected by Y2H. xref: IntAct:EBI-399495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023551 ! RAB5A_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0016230 name: ixl-crsp6-1 physical interaction comment: Interaction detected by Anti FLAG affinity chromatography. xref: IntAct:EBI-399508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0016231 name: ixl-crsp6-3 physical interaction comment: Interaction detected by Anti FLAG affinity chromatography. xref: IntAct:EBI-399538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0016232 name: ixl-crsp6-6 physical interaction comment: Interaction detected by Anti FLAG affinity chromatography. xref: IntAct:EBI-399950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0016233 name: q9nwa0-crsp6-2 physical interaction comment: Interaction detected by Anti FLAG affinity chromatography. xref: IntAct:EBI-399968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0016234 name: q9btt4-crsp6-1 physical interaction comment: Interaction detected by Anti FLAG affinity chromatography. xref: IntAct:EBI-399987 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0016235 name: q9nwa0-vdrip-3 physical interaction comment: Interaction detected by FLAG-IP. xref: IntAct:EBI-400050 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN [Term] id: CCO:I0016236 name: cdc42-was-5 physical interaction comment: circular dichroism : human cdc42 and human WASP xref: IntAct:EBI-457554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0016237 name: hd-git1-1 colocalization comment: Co-localization of huntingtin Q68 with GIT-1 C terminus fragment in cos-1 cells xref: IntAct:EBI-472913 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016238 name: hd-git1-2 physical interaction comment: Yeast two hybrid, bait= huntingtin prey=GIT1. deletion analysis of huntingtin. xref: IntAct:EBI-472926 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016239 name: hd-git1-3 physical interaction comment: Yeast two hybrid, bait= huntingtin prey=GIT1. deletion analysis of GIT1. xref: IntAct:EBI-472938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0016240 name: foxd3-pou5f1-1 physical interaction comment: Interaction detected by GST pulldown xref: IntAct:EBI-475717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016733 ! FOXD3_HUMAN relationship: has_participant CCO:B0048656 ! PO5F1_HUMAN [Term] id: CCO:I0016241 name: foxd3-pou5f1-2 physical interaction comment: Interaction detected by coimmunoprecipitation xref: IntAct:EBI-475728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016733 ! FOXD3_HUMAN relationship: has_participant CCO:B0048656 ! PO5F1_HUMAN [Term] id: CCO:I0016242 name: cdc42-ncf2-1 physical interaction comment: ITC: Only if mutated (K24A S30G), cdc42 can bind to P67 phox TPR domains xref: IntAct:EBI-489624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0063026 ! NCF2_HUMAN [Term] id: CCO:I0016243 name: rac1-ncf2-2 physical interaction comment: ITC: Human Rac1 Q61L GTP and P67 phox TPR domains xref: IntAct:EBI-489636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0063026 ! NCF2_HUMAN [Term] id: CCO:I0016244 name: rac2-ncf2-1 physical interaction comment: ITC: Human Rac2 Q61L GTP and P67 phox TPR domains xref: IntAct:EBI-489644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025802 ! RAC2_HUMAN relationship: has_participant CCO:B0063026 ! NCF2_HUMAN [Term] id: CCO:I0016245 name: rela-dhx9-2 physical interaction comment: Interaction of RELA with Flag-tagged DHX9 demonstrated by in vivo co-immunoprecipitation. xref: IntAct:EBI-491459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0016246 name: map4k5-crk-3 physical interaction comment: MAP4K5 -Crk identified by co-immunoprecipitation xref: IntAct:EBI-492226 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:I0016247 name: map4k1-crkl-5 physical interaction comment: MAP4K1 -CrkL identified by co-immunoprecipitation xref: IntAct:EBI-492261 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:I0016248 name: trib3-atf4-3 physical interaction comment: Interaction detected by Y2H xref: IntAct:EBI-492506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0021435 ! ATF4_HUMAN [Term] id: CCO:I0016249 name: nr3c1-smarca4-1 physical interaction xref: IntAct:EBI-493544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0054886 ! GCR_HUMAN [Term] id: CCO:I0016250 name: nr3c1-smarca4-2 physical interaction xref: IntAct:EBI-493549 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0054886 ! GCR_HUMAN [Term] id: CCO:I0016251 name: tnfrsf6-fadd-6 physical interaction comment: Interaction between FasLR and FADD demonstrated by GST-pull down xref: IntAct:EBI-494993 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0016252 name: tradd-traf2-1 physical interaction comment: late and long lasting complex (named complex II) after TNF alpha stimulation shown by CoIP (anti-Caspase-8) in HT1080 cell line after TNF alpha stimulation xref: IntAct:EBI-514691 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0016253 name: tradd-traf2-2 physical interaction comment: late and long lasting complex (named complex II) after TNF alpha stimulation shown by CoIP (anti-Caspase-8) in apoptosis-sensitive I-kBmut HT1080 cell line after TNF alpha stimulation xref: IntAct:EBI-514887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0058106 ! CASPA_HUMAN [Term] id: CCO:I0016254 name: tnfsf6-tnfrsf6-2 physical interaction comment: FAS DISC complex shown by immunoprecipitation (anti-caspase-8): Fas, FADD, caspase-8 xref: IntAct:EBI-515081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0016255 name: fadd-mbd4-1 physical interaction comment: The FADD protein interacts with the Methyl CpG binding protein 4 xref: IntAct:EBI-518117 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0063002 ! MBD4_HUMAN [Term] id: CCO:I0016256 name: mbd4-fadd-1 physical interaction comment: The Methyl CpG binding protein 4 interacts with the FADD protein in vivo xref: IntAct:EBI-518148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0063002 ! MBD4_HUMAN [Term] id: CCO:I0016257 name: insr-ywhab-2 physical interaction comment: Interaction between Insulin receptor1 and 14-3-3beta demonstrated by Y2H xref: IntAct:EBI-518520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN [Term] id: CCO:I0016258 name: casp2-cradd-4 physical interaction comment: In vivo Co-IP: bait= human caspase 2, prey = human RAIDD, prey= PIDD xref: IntAct:EBI-520495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0016259 name: birc2-casp7-1 physical interaction comment: GST pull-down : bait = C-IAP1, prey = caspase 7 xref: IntAct:EBI-523986 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0055530 ! CASP7_HUMAN [Term] id: CCO:I0016260 name: tr6-light physical interaction comment: Flag pulldown reveals interaction between the Tumor necrosis factor receptor superfamily member 6B precursor protein (TR6) and the Tumor necrosis factor ligand superfamily member 14 protein (LIGHT) xref: IntAct:EBI-524167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0054760 ! TNR6B_HUMAN [Term] id: CCO:I0016261 name: light-tr6 physical interaction comment: FACs analysis reveals interaction between the tumor necrosis factor ligand superfamily member 14 protein (LIGHT) and the Tumor necrosis factor receptor superfamily member 6B precursor protein (TR6) xref: IntAct:EBI-524191 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0054760 ! TNR6B_HUMAN [Term] id: CCO:I0016262 name: light-lt_beta-r physical interaction comment: FACs analysis reveals interaction between the tumor necrosis factor ligand superfamily member 14 protein (LIGHT) and the lymphotoxin-beta protein (LT_beta_R) xref: IntAct:EBI-524211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0055770 ! TNFC_HUMAN [Term] id: CCO:I0016263 name: light-hvem physical interaction comment: FACs analysis reveals interaction between the tumor necrosis factor ligand superfamily member 14 protein (LIGHT) and the tumor necrosis factor receptor superfamily member 6B precursor protein (HVEM) xref: IntAct:EBI-524243 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0054490 ! TNF14_HUMAN [Term] id: CCO:I0016264 name: traf6-a20 physical interaction comment: Coimmunoprecipitaion reveals interaction between the TNF receptor associated factor 6 (TRAF6) and the Tumor necrosis factor, alpha-induced protein 3 xref: IntAct:EBI-527666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0055134 ! TNAP3_HUMAN [Term] id: CCO:I0016265 name: traf6-cezanne physical interaction comment: Coimmunoprecipitaion reveals interaction between the TNF receptor associated factor 6 (TRAF6) and the Zinc finger A20 domain containing protein 1 (Cezanne) xref: IntAct:EBI-527796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0056735 ! OTU7B_HUMAN [Term] id: CCO:I0016266 name: traf6-trabid physical interaction comment: Coimmunoprecipitaion reveals interaction between the TNF receptor associated factor 6 (TRAF6) and the TRABID protein xref: IntAct:EBI-527861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0063027 ! ZRAN1_HUMAN [Term] id: CCO:I0016267 name: myd88-tirap-1 physical interaction comment: Coimmunoprecipitation reveals interaction between the myeloid differentiation primary response protein (MyD88) and the toll-interleukin 1 receptor domain-containing adapter protein xref: IntAct:EBI-528679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055572 ! TIRAP_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0016268 name: tirap-irak2 physical interaction comment: Coimmunoprecipitation reveals interaction between the toll-interleukin 1 receptor domain-containing adapter protein and the Interleukin-1 receptor-associated kinase-like 2 xref: IntAct:EBI-528692 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0055572 ! TIRAP_HUMAN [Term] id: CCO:I0016269 name: tirap-tlr4 physical interaction comment: Coimmunoprecipitation reveals interaction between the toll-interleukin 1 receptor domain-containing adapter protein and the Toll-like receptor 4 precursor xref: IntAct:EBI-528743 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022071 ! TLR4_HUMAN relationship: has_participant CCO:B0055572 ! TIRAP_HUMAN [Term] id: CCO:I0016270 name: cd40-traf3-2 physical interaction comment: GST pulldown reveals interaction between the CD40 protein and the TNF receptor associated factor 3 (TRAF3) xref: IntAct:EBI-528820 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055188 ! TNR5_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN [Term] id: CCO:I0016271 name: ikk-csn3 physical interaction comment: Yeast-2-hybrid reveals interaction between the NF-kappa-B essential modulator protein (IKK gamma) and the COP9 signalosome complex subunit 3 protein xref: IntAct:EBI-530740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0016272 name: raf1-ywhab-1 physical interaction comment: Y2H: bait = C-Raf ,prey = 14-3-3 beta xref: IntAct:EBI-537209 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0016273 name: raf1-oip5 physical interaction comment: Y2H: bait = C-Raf ,prey = OIP5-OIP5_HUMAN xref: IntAct:EBI-537223 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063028 ! OIP5_HUMAN [Term] id: CCO:I0016274 name: raf1-pkm2 physical interaction comment: Y2H: bait = C-Raf ,prey = PyK-KPYM_HUMAN xref: IntAct:EBI-537230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:I0016275 name: raf1-cct3 physical interaction comment: Y2H: bait = C-Raf ,prey = CCT3-TCPG_HUMAN xref: IntAct:EBI-537237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0016276 name: stn2-syt1-1 colocalization comment: Synaptotagmin I recruits stonin 2 at the plasma membrane xref: IntAct:EBI-539760 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0040103 ! SYT1_HUMAN relationship: has_participant CCO:B0058016 ! STON2_HUMAN [Term] id: CCO:I0016277 name: ppie-mll-2 physical interaction comment: Interaction of Cyp33 and MLL, as detected by GST pull down. xref: IntAct:EBI-591841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005486 ! HRX_HUMAN relationship: has_participant CCO:B0059255 ! PPIE_HUMAN [Term] id: CCO:I0016278 name: wasp-cdc42-1 direct interaction comment: RMN: structure of Cdc42 in complex with the effector WASP xref: IntAct:EBI-603513 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0016279 name: gpsm2-gpsm2-4 physical interaction xref: IntAct:EBI-621869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0016280 name: gpsm2-gpsm2-5 physical interaction xref: IntAct:EBI-621885 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0016281 name: cir-sfrs2-1 physical interaction comment: CIR interacts with SR proteins, as detected by Y2H. xref: IntAct:EBI-630737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:I0016282 name: cir-u2af1-1 physical interaction comment: CIR interacts with SR proteins, as detected by Y2H. xref: IntAct:EBI-632474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:I0016283 name: cir-sfrs1-1 physical interaction comment: CIR interacts with SR proteins, as detected by Y2H. xref: IntAct:EBI-632478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0016284 name: cir-rbpsuh-1 physical interaction comment: Interaction of CIR and CBF-1, detected by yeast two hybrid. xref: IntAct:EBI-632576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055767 ! SUH_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0016285 name: eif4g1-eif4a1-3 physical interaction comment: Interaction of eIF4G1 with eIF4AI identified by His pulldown xref: IntAct:EBI-633422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0016286 name: eif4g1-eif4a2-3 physical interaction comment: Interaction of eIF4G1 with eIF4AII identified by His pulldown xref: IntAct:EBI-633430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0016287 name: dyrk1b-ranbp9-2 direct interaction comment: Interaction between DYRK1B and RANBP9 identified by GST pulldown xref: IntAct:EBI-636117 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN relationship: has_participant CCO:B0063004 ! RANB9_HUMAN [Term] id: CCO:I0016288 name: dyrk1b-tcf1-3 phosphorylation comment: Phosphorylation of TCF1 (HNF1alpha) by DYRK1B identified by in vitro kinase assay xref: IntAct:EBI-636178 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0016289 name: arid1a-smarca4- physical interaction comment: coIP: bait = baf250a; prey = brg1 xref: IntAct:EBI-637905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0016290 name: itgb7-itgb7-1 physical interaction comment: GALLEX: Homodimerization of integrin beta 7 xref: IntAct:EBI-702953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033137 ! ITB7_HUMAN [Term] id: CCO:I0016291 name: itga2-itga2-1 physical interaction comment: GALLEX: Homodimerization of integrin alpha2 xref: IntAct:EBI-702975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050196 ! ITA2_HUMAN [Term] id: CCO:I0016292 name: itga2b-itga2b-6 physical interaction comment: GALLEX: Homodimerization of integrin alpha II b TM region xref: IntAct:EBI-703024 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:I0016293 name: itga4-itga4-1 physical interaction comment: GALLEX: Homodimerization of integrin alpha 4 xref: IntAct:EBI-703050 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055015 ! ITA4_HUMAN [Term] id: CCO:I0016294 name: itgb1-itgb1-1 physical interaction comment: GALLEX: Homodimerization of integrin beta 1 xref: IntAct:EBI-703110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033138 ! ITB1_HUMAN [Term] id: CCO:I0016295 name: itgb3-itgb3-3 physical interaction comment: GALLEX: Homodimerization of integrin beta 3 xref: IntAct:EBI-703126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0016296 name: itga2-itga2-2 physical interaction comment: GALLEX: Homodimerization of integrin alpha2 xref: IntAct:EBI-703150 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050196 ! ITA2_HUMAN [Term] id: CCO:I0016297 name: itga2b-itga2b-7 physical interaction comment: GALLEX: Homodimerization of integrin alpha II b TM region xref: IntAct:EBI-703166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:I0016298 name: itga4-itga4-2 physical interaction comment: GALLEX: Homodimerization of integrin alpha 4 xref: IntAct:EBI-703182 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055015 ! ITA4_HUMAN [Term] id: CCO:I0016299 name: itgb1-itgb1-2 physical interaction comment: GALLEX: Homodimerization of integrin beta 1 xref: IntAct:EBI-703198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033138 ! ITB1_HUMAN [Term] id: CCO:I0016300 name: itgb3-itgb3-4 physical interaction comment: GALLEX: Homodimerization of integrin beta 3 xref: IntAct:EBI-703214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0016301 name: itgb7-itgb7-2 physical interaction comment: GALLEX: Homodimerization of integrin beta 7 xref: IntAct:EBI-703230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033137 ! ITB7_HUMAN [Term] id: CCO:I0016302 name: itga2-itgb1-1 physical interaction comment: GALLEX: Heterodimerization of integrin alpha2 with integrin beta 1 xref: IntAct:EBI-703266 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033138 ! ITB1_HUMAN relationship: has_participant CCO:B0050196 ! ITA2_HUMAN [Term] id: CCO:I0016303 name: itga2b-itgb3-1 physical interaction comment: GALLEX: Heterodimerization of integrin alpha II b with inegrin beta 3 xref: IntAct:EBI-703283 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0016304 name: itga4-itgb1-1 physical interaction comment: GALLEX: Heterodimerization of integrin alpha 4 with integrin beta 1 xref: IntAct:EBI-703300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033138 ! ITB1_HUMAN relationship: has_participant CCO:B0055015 ! ITA4_HUMAN [Term] id: CCO:I0016305 name: itga4-itgb7-2 physical interaction comment: GALLEX: Heterodimerization of integrin alpha 4 with integrin beta 7 xref: IntAct:EBI-703317 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033137 ! ITB7_HUMAN relationship: has_participant CCO:B0055015 ! ITA4_HUMAN [Term] id: CCO:I0016306 name: itgb1-itga2-1 physical interaction comment: GALLEX: Heterodimerization of integrin beta 1 with integrin alpha 2 xref: IntAct:EBI-703334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033138 ! ITB1_HUMAN relationship: has_participant CCO:B0050196 ! ITA2_HUMAN [Term] id: CCO:I0016307 name: itgb1-itga4-1 physical interaction comment: GALLEX: Heterodimerization of integrin beta 1 with integrin alpha 4 xref: IntAct:EBI-703351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033138 ! ITB1_HUMAN relationship: has_participant CCO:B0055015 ! ITA4_HUMAN [Term] id: CCO:I0016308 name: itgb3-itga2b-1 physical interaction comment: GALLEX: Heterodimerization of integrin beta 3 with integrin alpha II b xref: IntAct:EBI-703368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0016309 name: itgb7-itga4-1 physical interaction comment: GALLEX: Heterodimerization of integrin beta 7 with integrin alpha 4 xref: IntAct:EBI-703385 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033137 ! ITB7_HUMAN relationship: has_participant CCO:B0055015 ! ITA4_HUMAN [Term] id: CCO:I0016310 name: irk2-akap5-3 physical interaction comment: GST pull-down: bait = kir2.1, prey = AKAP79 (AKAP5) xref: IntAct:EBI-703667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030995 ! IRK2_HUMAN relationship: has_participant CCO:B0055172 ! AKAP5_HUMAN [Term] id: CCO:I0016311 name: app-apoa1-3 physical interaction comment: Interaction of Apolipoprotein A-1 with ectodomain of Amyloid Precursor Protein detected in vitro. xref: IntAct:EBI-703771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN [Term] id: CCO:I0016312 name: ptprn-ptprt-3 physical interaction comment: Co-IP: bait = PTP rho, prey = IA-2 intracellular domain xref: IntAct:EBI-728331 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023006 ! PTPRT_HUMAN relationship: has_participant CCO:B0025847 ! PTPRN_HUMAN [Term] id: CCO:I0016313 name: accn2-prkpcabp-2 physical interaction xref: IntAct:EBI-79211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0055639 ! ACCN2_HUMAN [Term] id: CCO:I0016314 name: rar-mbd1-1 physical interaction comment: MBD1 interaction with RAR and HA-MBD1 detected using CoIP. xref: IntAct:EBI-867347 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005510 ! MBD1_HUMAN relationship: has_participant CCO:B0024853 ! RARA_HUMAN [Term] id: CCO:I0016315 name: erbb3-erbb2-3 physical interaction comment: Interaction between human erbB3 and erbB2 detected by coIP xref: IntAct:EBI-875556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN [Term] id: CCO:I0016316 name: erbb3-erbb4-2 physical interaction comment: Interaction between human erbB3 and erbB4 detected by coIP xref: IntAct:EBI-875560 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:I0016317 name: p85a-erbb3-1 physical interaction comment: Interaction between human P85A and erbB3 detected by coIP xref: IntAct:EBI-875564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0016318 name: gemin5-eif4e direct interaction xref: IntAct:EBI-876627 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0062979 ! GEMI5_HUMAN [Term] id: CCO:I0016319 name: maml-notch physical interaction xref: IntAct:EBI-908262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0058068 ! MAML1_HUMAN [Term] id: CCO:I0016320 name: lef1-tle1-1 direct interaction comment: Interaction between human LEF1 and TLE1 detected by far western xref: IntAct:EBI-926159 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0059175 ! LEF1_HUMAN [Term] id: CCO:I0016321 name: smarca5-myo1c physical interaction xref: IntAct:EBI-935073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027842 ! MYH1_HUMAN relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0016322 name: smarca5-baz2a physical interaction xref: IntAct:EBI-935082 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0059160 ! BAZ2A_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0016323 name: arhgap24-flna-3 physical interaction comment: Interaction between ARHGAP24 and FLNA identified by coimmunoprecipitation xref: IntAct:EBI-988878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0016324 name: arhgap24-flna-4 physical interaction comment: Interaction between ARHGAP24 and FLNA identified by coimmunoprecipitation xref: IntAct:EBI-988891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0016325 name: ppp2r5d-ppp2r5a-1 physical interaction xref: IntAct:EBI-989261 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN [Term] id: CCO:I0016326 name: magi1-adrb1-1 direct interaction comment: Interaction between MAGI1 and ADRB1 demonstrated by peptide array xref: IntAct:EBI-991002 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054929 ! ADRB1_HUMAN relationship: has_participant CCO:B0058358 ! MAGI1_HUMAN [Term] id: CCO:I0016327 name: magi2-adrb1-2 direct interaction comment: Interaction between MAGI2 and ADRB1 demonstrated by peptide array xref: IntAct:EBI-991035 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054929 ! ADRB1_HUMAN relationship: has_participant CCO:B0063032 ! MAGI2_HUMAN [Term] id: CCO:I0016328 name: magi2-adrb1-1 direct interaction comment: Interaction between MAGI2 and ADRB1 demonstrated by peptide array xref: IntAct:EBI-991049 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054929 ! ADRB1_HUMAN relationship: has_participant CCO:B0063032 ! MAGI2_HUMAN [Term] id: CCO:I0016329 name: gopc-adrb1-1 direct interaction comment: Interaction between GOPC and ADRB1 demonstrated by peptide array xref: IntAct:EBI-991131 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054929 ! ADRB1_HUMAN relationship: has_participant CCO:B0063033 ! GOPC_HUMAN [Term] id: CCO:I0016330 name: rraga-rragc-3 physical interaction xref: IntAct:EBI-993014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0016331 name: rraga-rragd-3 physical interaction xref: IntAct:EBI-993021 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0063034 ! RRAGD_HUMAN [Term] id: CCO:I0016332 name: rragb-rragc-1 physical interaction xref: IntAct:EBI-993067 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056676 ! RRAGB_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0016333 name: rragb-rragd-1 physical interaction xref: IntAct:EBI-993079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056676 ! RRAGB_HUMAN relationship: has_participant CCO:B0063034 ! RRAGD_HUMAN [Term] id: CCO:I0016334 name: rragc-rraga-4 physical interaction xref: IntAct:EBI-993093 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0016335 name: rragd-rraga-4 physical interaction xref: IntAct:EBI-993102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0063034 ! RRAGD_HUMAN [Term] id: CCO:I0016336 name: mll2-rbq3-1 physical interaction xref: IntAct:EBI-996195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0006000 ! WDR5B_HUMAN relationship: has_participant CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:I0016337 name: eps15-hrb-1 physical interaction xref: IntAct:EBI-996590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005424 ! EP15_HUMAN relationship: has_participant CCO:B0055487 ! NUPL_HUMAN [Term] id: CCO:I0016338 name: stambp-stam-2 physical interaction xref: IntAct:EBI-996797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0058093 ! STAM1_HUMAN [Term] id: CCO:I0016339 name: nck1-nphs1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between Nephrin protein and NCK1 protein xref: IntAct:EBI-996967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0062983 ! NPHN_HUMAN [Term] id: CCO:I0016340 name: nck1-nphs1-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between Nephrin protein and NCK1 protein xref: IntAct:EBI-997348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0062983 ! NPHN_HUMAN [Term] id: CCO:I0016341 name: stambp-stam-3 physical interaction xref: IntAct:EBI-999135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0058093 ! STAM1_HUMAN [Term] id: CCO:I0016342 name: map3k8-hspa9b physical interaction xref: IntAct:EBI-360705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016343 name: map3k8-eef1a2 physical interaction xref: IntAct:EBI-360714 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0016344 name: map3k8-lgals3bp physical interaction xref: IntAct:EBI-360720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0055789 ! LG3BP_HUMAN [Term] id: CCO:I0016345 name: map3k8-nfkb2 physical interaction xref: IntAct:EBI-360744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0016346 name: map3k8-sptbn1 physical interaction xref: IntAct:EBI-360750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0016347 name: map3k8-hspca physical interaction xref: IntAct:EBI-360756 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016348 name: rel-hspa1l physical interaction xref: IntAct:EBI-360765 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023825 ! HS71L_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016349 name: rel-hspa5 physical interaction xref: IntAct:EBI-360768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016350 name: rel-hspa8 physical interaction xref: IntAct:EBI-360771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016351 name: rel-hspa9b physical interaction xref: IntAct:EBI-360774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016352 name: rel-nfkbie physical interaction xref: IntAct:EBI-360777 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016353 name: rel-hspa6 physical interaction xref: IntAct:EBI-360780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023839 ! HSP76_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016354 name: rel-hnrph1 physical interaction xref: IntAct:EBI-360783 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005732 ! HNRH1_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016355 name: rel-c1qbp physical interaction xref: IntAct:EBI-360786 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0016356 name: rel-nfkbia physical interaction xref: IntAct:EBI-360789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016357 name: rel-nfkbib physical interaction xref: IntAct:EBI-360792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016358 name: rel-nfkb1 physical interaction xref: IntAct:EBI-360795 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016359 name: rel-actg1 physical interaction xref: IntAct:EBI-360798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015628 ! ACTG_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016360 name: rel-cltc physical interaction xref: IntAct:EBI-360801 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016361 name: rel-rel physical interaction xref: IntAct:EBI-360804 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016362 name: rel-wdr37 physical interaction xref: IntAct:EBI-360807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0063036 ! WDR37_HUMAN [Term] id: CCO:I0016363 name: rel-hsp70_1 physical interaction xref: IntAct:EBI-360810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016364 name: rel-nfkb2 physical interaction xref: IntAct:EBI-360825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016365 name: rel-q9bzf9 physical interaction xref: IntAct:EBI-360828 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0063038 ! UACA_HUMAN [Term] id: CCO:I0016366 name: rel-fkbp5 physical interaction xref: IntAct:EBI-360831 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0063039 ! FKBP5_HUMAN [Term] id: CCO:I0016367 name: rel-gapd physical interaction xref: IntAct:EBI-360834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016368 name: rel-tuba2 physical interaction xref: IntAct:EBI-360837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0016369 name: nfkbia-hspa1l physical interaction xref: IntAct:EBI-360840 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016370 name: nfkbia-hspa5 physical interaction xref: IntAct:EBI-360843 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016371 name: nfkbia-hspa8 physical interaction xref: IntAct:EBI-360846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016372 name: nfkbia-slc25a5 physical interaction xref: IntAct:EBI-360852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0016373 name: nfkbia-hspa9b physical interaction xref: IntAct:EBI-360855 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016374 name: nfkbia-rpl23 physical interaction xref: IntAct:EBI-360858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:I0016375 name: nfkbia-polrmt physical interaction xref: IntAct:EBI-360861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0063040 ! RPOM_HUMAN [Term] id: CCO:I0016376 name: nfkbia-nfkbia physical interaction xref: IntAct:EBI-360867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:I0016377 name: nfkbia-nfkb1 physical interaction xref: IntAct:EBI-360870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0016378 name: nfkbia-actg1 physical interaction xref: IntAct:EBI-360873 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016379 name: nfkbia-vcp physical interaction xref: IntAct:EBI-360876 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:I0016380 name: nfkbia-cltc physical interaction xref: IntAct:EBI-360882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016381 name: nfkbia-hsp70_1 physical interaction xref: IntAct:EBI-360885 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016382 name: nfkbia-sprr3 physical interaction xref: IntAct:EBI-360891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0063041 ! SPRR3_HUMAN [Term] id: CCO:I0016383 name: nfkbia-nfkb2 physical interaction xref: IntAct:EBI-360903 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0016384 name: nfkbia-tuba2 physical interaction xref: IntAct:EBI-360912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016385 name: nfkbia-ptpn13 physical interaction xref: IntAct:EBI-360915 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0063042 ! PTN13_HUMAN [Term] id: CCO:I0016386 name: nfkbia-tuba1 physical interaction xref: IntAct:EBI-360918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:I0016387 name: nfkbib-bag2 physical interaction xref: IntAct:EBI-360921 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN [Term] id: CCO:I0016388 name: nfkbib-hspa1l physical interaction xref: IntAct:EBI-360924 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016389 name: nfkbib-hspa5 physical interaction xref: IntAct:EBI-360927 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016390 name: nfkbib-hspa8 physical interaction xref: IntAct:EBI-360930 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016391 name: nfkbib-s100a8 physical interaction xref: IntAct:EBI-360933 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0006159 ! S10A8_HUMAN [Term] id: CCO:I0016392 name: nfkbib-hspa9b physical interaction xref: IntAct:EBI-360936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016393 name: nfkbib-slpi physical interaction xref: IntAct:EBI-360939 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063044 ! SLPI_HUMAN [Term] id: CCO:I0016394 name: nfkbib-iqgap1 physical interaction xref: IntAct:EBI-360942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:I0016395 name: nfkbib-iars physical interaction xref: IntAct:EBI-360945 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063045 ! SYIC_HUMAN [Term] id: CCO:I0016396 name: nfkbib-eprs physical interaction xref: IntAct:EBI-360948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:I0016397 name: nfkbib-nfkbib physical interaction xref: IntAct:EBI-360951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0016398 name: nfkbib-lyz physical interaction xref: IntAct:EBI-360954 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063047 ! LYSC_HUMAN [Term] id: CCO:I0016399 name: nfkbib-actg1 physical interaction xref: IntAct:EBI-360957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016400 name: nfkbib-vcp physical interaction xref: IntAct:EBI-360960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:I0016401 name: nfkbib-tbp physical interaction xref: IntAct:EBI-360963 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0016402 name: nfkbib-cltc physical interaction xref: IntAct:EBI-360969 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016403 name: nfkbib-rpl35a physical interaction xref: IntAct:EBI-360972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063048 ! RL35A_HUMAN [Term] id: CCO:I0016404 name: nfkbib-rpl7 physical interaction xref: IntAct:EBI-360975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005746 ! RL7_HUMAN [Term] id: CCO:I0016405 name: nfkbib-hsp70_1 physical interaction xref: IntAct:EBI-360978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016406 name: nfkbib-sec8l1 physical interaction xref: IntAct:EBI-360981 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063049 ! EXOC4_HUMAN [Term] id: CCO:I0016407 name: nfkbib-srprb physical interaction xref: IntAct:EBI-360987 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0006313 ! SRPRB_HUMAN [Term] id: CCO:I0016408 name: nfkbib-nfkb2 physical interaction xref: IntAct:EBI-360999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0016409 name: nfkbib-dkfzp761m0817 physical interaction xref: IntAct:EBI-361002 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:I0016410 name: nfkbib-q8nhw5 physical interaction xref: IntAct:EBI-361005 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063050 ! RLA0L_HUMAN [Term] id: CCO:I0016411 name: nfkbib-ok/sw_cl_108 physical interaction xref: IntAct:EBI-361008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0026171 ! KI18A_HUMAN [Term] id: CCO:I0016412 name: nfkbib-znrd1 physical interaction xref: IntAct:EBI-361011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005622 ! RPA12_HUMAN [Term] id: CCO:I0016413 name: nfkbib-polr1b physical interaction xref: IntAct:EBI-361014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0049473 ! RPA2_HUMAN [Term] id: CCO:I0016414 name: nfkbib-hnrpu physical interaction xref: IntAct:EBI-361017 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:I0016415 name: nfkbib-sfpq physical interaction xref: IntAct:EBI-361023 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0016416 name: nfkbib-dsp physical interaction xref: IntAct:EBI-361026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:I0016417 name: nfkbib-q8iwp9 physical interaction xref: IntAct:EBI-361029 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063052 ! CC28A_HUMAN [Term] id: CCO:I0016418 name: nfkbib-hspca physical interaction xref: IntAct:EBI-361032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016419 name: nfkbib-ncl physical interaction xref: IntAct:EBI-361035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:I0016420 name: nfkbib-tuba2 physical interaction xref: IntAct:EBI-361038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016421 name: nfkbib-tuba1 physical interaction xref: IntAct:EBI-361053 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:I0016422 name: nfkbie-ikbkg physical interaction xref: IntAct:EBI-361062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:I0016423 name: nfkbie-hspa9b physical interaction xref: IntAct:EBI-361080 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016424 name: nfkbie-ruvbl2 physical interaction xref: IntAct:EBI-361083 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:I0016425 name: nfkbie-nfkb1 physical interaction xref: IntAct:EBI-361101 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0016426 name: nfkbie-vcp physical interaction xref: IntAct:EBI-361104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:I0016427 name: nfkbie-nfkb2 physical interaction xref: IntAct:EBI-361125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:I0016428 name: nfkbie-arhgef2 physical interaction xref: IntAct:EBI-361134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0063053 ! ARHG2_HUMAN [Term] id: CCO:I0016429 name: nfkbie-sfpq physical interaction xref: IntAct:EBI-361137 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0016430 name: nfkbie-hspca physical interaction xref: IntAct:EBI-361143 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016431 name: chuk-ikbkg physical interaction xref: IntAct:EBI-361161 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0016432 name: chuk-chuk physical interaction xref: IntAct:EBI-361164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0016433 name: chuk-capza1 physical interaction xref: IntAct:EBI-361167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0037567 ! CAZA1_HUMAN [Term] id: CCO:I0016434 name: chuk-hspa9b physical interaction xref: IntAct:EBI-361170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016435 name: chuk-eef1a2 physical interaction xref: IntAct:EBI-361173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0016436 name: chuk-nfkbib physical interaction xref: IntAct:EBI-361176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0016437 name: chuk-actg1 physical interaction xref: IntAct:EBI-361182 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016438 name: chuk-cltc physical interaction xref: IntAct:EBI-361185 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016439 name: chuk-hsp70_1 physical interaction xref: IntAct:EBI-361188 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016440 name: chuk-myh14 physical interaction xref: IntAct:EBI-361197 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0005971 ! MYH14_HUMAN [Term] id: CCO:I0016441 name: chuk-myh9 physical interaction xref: IntAct:EBI-361203 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0016442 name: chuk-tpm3 physical interaction xref: IntAct:EBI-361206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0063054 ! TPM3_HUMAN [Term] id: CCO:I0016443 name: chuk-myl6 physical interaction xref: IntAct:EBI-361209 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:I0016444 name: chuk-tuba2 physical interaction xref: IntAct:EBI-361212 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016445 name: chuk-mlcb physical interaction xref: IntAct:EBI-361218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:I0016446 name: chuk-myo1d physical interaction xref: IntAct:EBI-361221 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0063055 ! MYO1D_HUMAN [Term] id: CCO:I0016447 name: ikbkb-ikbkg physical interaction xref: IntAct:EBI-361224 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0016448 name: ikbkb-hspa1l physical interaction xref: IntAct:EBI-361227 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016449 name: ikbkb-hspa5 physical interaction xref: IntAct:EBI-361230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016450 name: ikbkb-hspa8 physical interaction xref: IntAct:EBI-361233 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016451 name: ikbkb-chuk physical interaction xref: IntAct:EBI-361236 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0016452 name: ikbkb-hspa9b physical interaction xref: IntAct:EBI-361239 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016453 name: ikbkb-iqgap1 physical interaction xref: IntAct:EBI-361242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:I0016454 name: ikbkb-eprs physical interaction xref: IntAct:EBI-361245 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:I0016455 name: ikbkb-c1qbp physical interaction xref: IntAct:EBI-361248 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0016456 name: ikbkb-baf155 physical interaction xref: IntAct:EBI-361251 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0016457 name: ikbkb-lyz physical interaction xref: IntAct:EBI-361254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0063047 ! LYSC_HUMAN [Term] id: CCO:I0016458 name: ikbkb-actg1 physical interaction xref: IntAct:EBI-361260 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016459 name: ikbkb-cltc physical interaction xref: IntAct:EBI-361266 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016460 name: ikbkb-ikbkb physical interaction xref: IntAct:EBI-361269 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0016461 name: ikbkb-hsp70_1 physical interaction xref: IntAct:EBI-361275 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016462 name: ikbkb-flna physical interaction xref: IntAct:EBI-361287 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:I0016463 name: ikbkb-hnrpu physical interaction xref: IntAct:EBI-361290 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:I0016464 name: ikbkb-adprt physical interaction xref: IntAct:EBI-361293 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005467 ! PARP1_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0016465 name: ikbkb-tuba2 physical interaction xref: IntAct:EBI-361296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016466 name: ikbke-hspa8 physical interaction xref: IntAct:EBI-361302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016467 name: ikbke-hspa9b physical interaction xref: IntAct:EBI-361308 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016468 name: ikbke-cct5 physical interaction xref: IntAct:EBI-361311 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005291 ! TCPE_HUMAN relationship: has_participant CCO:B0005523 ! IKKE_HUMAN [Term] id: CCO:I0016469 name: ikbke-o43809 physical interaction xref: IntAct:EBI-361314 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0062837 ! CPSF5_HUMAN [Term] id: CCO:I0016470 name: ikbke-hnrph1 physical interaction xref: IntAct:EBI-361317 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:I0016471 name: ikbke-sptan1 physical interaction xref: IntAct:EBI-361320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0016472 name: ikbke-actg1 physical interaction xref: IntAct:EBI-361329 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016473 name: ikbke-tfrc physical interaction xref: IntAct:EBI-361332 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0063056 ! TFR1_HUMAN [Term] id: CCO:I0016474 name: ikbke-lgals3bp physical interaction xref: IntAct:EBI-361335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0055789 ! LG3BP_HUMAN [Term] id: CCO:I0016475 name: ikbke-cltc physical interaction xref: IntAct:EBI-361338 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016476 name: ikbke-ikbke physical interaction xref: IntAct:EBI-361341 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN [Term] id: CCO:I0016477 name: ikbke-traf2 physical interaction xref: IntAct:EBI-361344 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005523 ! IKKE_HUMAN [Term] id: CCO:I0016478 name: ikbke-hsp70_1 physical interaction xref: IntAct:EBI-361347 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016479 name: ikbke-myo6 physical interaction xref: IntAct:EBI-361350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:I0016480 name: ikbke-myh9 physical interaction xref: IntAct:EBI-361365 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0016481 name: ikbke-sptbn1 physical interaction xref: IntAct:EBI-361368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0016482 name: ikbke-dsp physical interaction xref: IntAct:EBI-361371 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:I0016483 name: ikbke-tpm3 physical interaction xref: IntAct:EBI-361374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0063054 ! TPM3_HUMAN [Term] id: CCO:I0016484 name: ikbke-myl6 physical interaction xref: IntAct:EBI-361377 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:I0016485 name: ikbke-tuba2 physical interaction xref: IntAct:EBI-361380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016486 name: ikbke-mlcb physical interaction xref: IntAct:EBI-361386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:I0016487 name: ikbkg-vars2 physical interaction xref: IntAct:EBI-361389 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063057 ! SYVC_HUMAN [Term] id: CCO:I0016488 name: ikbkg-lrpprc physical interaction xref: IntAct:EBI-361392 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005755 ! LPPRC_HUMAN [Term] id: CCO:I0016489 name: ikbkg-ikbkg physical interaction xref: IntAct:EBI-361398 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0016490 name: ikbkg-hspa1l physical interaction xref: IntAct:EBI-361401 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016491 name: ikbkg-hspa5 physical interaction xref: IntAct:EBI-361404 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016492 name: ikbkg-dbn1 physical interaction xref: IntAct:EBI-361407 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:I0016493 name: ikbkg-ighg3 physical interaction xref: IntAct:EBI-361410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0034291 ! IGHG3_HUMAN [Term] id: CCO:I0016494 name: ikbkg-rars physical interaction xref: IntAct:EBI-361413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063058 ! SYRC_HUMAN [Term] id: CCO:I0016495 name: ikbkg-capza1 physical interaction xref: IntAct:EBI-361416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0037567 ! CAZA1_HUMAN [Term] id: CCO:I0016496 name: ikbkg-slc25a5 physical interaction xref: IntAct:EBI-361422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0016497 name: ikbkg-atp5o physical interaction xref: IntAct:EBI-361425 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063059 ! ATPO_HUMAN [Term] id: CCO:I0016498 name: ikbkg-hspa9b physical interaction xref: IntAct:EBI-361428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016499 name: ikbkg-mars physical interaction xref: IntAct:EBI-361434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063060 ! SYMC_HUMAN [Term] id: CCO:I0016500 name: ikbkg-rps5 physical interaction xref: IntAct:EBI-361437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063061 ! RS5_HUMAN [Term] id: CCO:I0016501 name: ikbkg-rps10 physical interaction xref: IntAct:EBI-361440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005749 ! RS10_HUMAN [Term] id: CCO:I0016502 name: ikbkg-rplp2 physical interaction xref: IntAct:EBI-361443 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:I0016503 name: ikbkg-sfxn1 physical interaction xref: IntAct:EBI-361446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063062 ! SFXN1_HUMAN [Term] id: CCO:I0016504 name: ikbkg-crm1 physical interaction xref: IntAct:EBI-361449 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005867 ! XPO1_HUMAN [Term] id: CCO:I0016505 name: ikbkg-rpl23 physical interaction xref: IntAct:EBI-361452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:I0016506 name: ikbkg-myo1c physical interaction xref: IntAct:EBI-361455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063063 ! MYO1C_HUMAN [Term] id: CCO:I0016507 name: ikbkg-eppk1 physical interaction xref: IntAct:EBI-361458 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:I0016508 name: ikbkg-rps3 physical interaction xref: IntAct:EBI-361461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:I0016509 name: ikbkg-trim28 physical interaction xref: IntAct:EBI-361464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:I0016510 name: ikbkg-hspa6 physical interaction xref: IntAct:EBI-361467 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0023839 ! HSP76_HUMAN [Term] id: CCO:I0016511 name: ikbkg-rps20 physical interaction xref: IntAct:EBI-361470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005563 ! RS20_HUMAN [Term] id: CCO:I0016512 name: ikbkg-kif5b physical interaction xref: IntAct:EBI-361473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005599 ! KINH_HUMAN [Term] id: CCO:I0016513 name: ikbkg-iars physical interaction xref: IntAct:EBI-361476 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063045 ! SYIC_HUMAN [Term] id: CCO:I0016514 name: ikbkg-gnb2l1 physical interaction xref: IntAct:EBI-361479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005739 ! GBLP_HUMAN [Term] id: CCO:I0016515 name: ikbkg-eef1a2 physical interaction xref: IntAct:EBI-361482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0016516 name: ikbkg-q9h853 physical interaction xref: IntAct:EBI-361488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063064 ! TBA4B_HUMAN [Term] id: CCO:I0016517 name: ikbkg-dap3 physical interaction xref: IntAct:EBI-361491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0055464 ! RT29_HUMAN [Term] id: CCO:I0016518 name: ikbkg-q9bzt1 physical interaction xref: IntAct:EBI-361494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063065 ! Q9BZT1_HUMAN [Term] id: CCO:I0016519 name: ikbkg-cad physical interaction xref: IntAct:EBI-361503 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0016520 name: ikbkg-canx physical interaction xref: IntAct:EBI-361506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063067 ! CALX_HUMAN [Term] id: CCO:I0016521 name: ikbkg-actg1 physical interaction xref: IntAct:EBI-361509 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016522 name: ikbkg-q9bsj8 physical interaction xref: IntAct:EBI-361512 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063068 ! ESYT1_HUMAN [Term] id: CCO:I0016523 name: ikbkg-cltc physical interaction xref: IntAct:EBI-361518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016524 name: ikbkg-rpn1 physical interaction xref: IntAct:EBI-361521 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0040688 ! RPN1_HUMAN [Term] id: CCO:I0016525 name: ikbkg-rps14 physical interaction xref: IntAct:EBI-361524 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:I0016526 name: ikbkg-f7 physical interaction xref: IntAct:EBI-361527 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063069 ! FA7_HUMAN [Term] id: CCO:I0016527 name: ikbkg-idh3a physical interaction xref: IntAct:EBI-361530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063070 ! IDH3A_HUMAN [Term] id: CCO:I0016528 name: ikbkg-hsp70_1 physical interaction xref: IntAct:EBI-361539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016529 name: ikbkg-hspa8 physical interaction xref: IntAct:EBI-361542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016530 name: ikbkg-myo6 physical interaction xref: IntAct:EBI-361545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:I0016531 name: ikbkg-set physical interaction xref: IntAct:EBI-361548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005519 ! SET_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0016532 name: ikbkg-q96ri3 physical interaction xref: IntAct:EBI-361551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063071 ! Q96RI3_HUMAN [Term] id: CCO:I0016533 name: ikbkg-drim physical interaction xref: IntAct:EBI-361557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0054662 ! UTP20_HUMAN [Term] id: CCO:I0016534 name: ikbkg-rplp0 physical interaction xref: IntAct:EBI-361560 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005762 ! RLA0_HUMAN [Term] id: CCO:I0016535 name: ikbkg-psmd13 physical interaction xref: IntAct:EBI-361563 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0030887 ! PSD13_HUMAN [Term] id: CCO:I0016536 name: ikbkg-kiaa1352 physical interaction xref: IntAct:EBI-361566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063072 ! SYLC_HUMAN [Term] id: CCO:I0016537 name: ikbkg-ighg1 physical interaction xref: IntAct:EBI-361575 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN [Term] id: CCO:I0016538 name: ikbkg-ikbkg-1 physical interaction xref: IntAct:EBI-361584 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0030841 ! Q7Z7F1_HUMAN [Term] id: CCO:I0016539 name: ikbkg-q86tt2 physical interaction xref: IntAct:EBI-361590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0034311 ! Q86TT2_HUMAN [Term] id: CCO:I0016540 name: ikbkg-q8n4y9 physical interaction xref: IntAct:EBI-361593 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0034304 ! Q8N4Y9_HUMAN [Term] id: CCO:I0016541 name: ikbkg-q8nhw5 physical interaction xref: IntAct:EBI-361596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063050 ! RLA0L_HUMAN [Term] id: CCO:I0016542 name: ikbkg-vdp physical interaction xref: IntAct:EBI-361602 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063073 ! USO1_HUMAN [Term] id: CCO:I0016543 name: ikbkg-ywhaz physical interaction xref: IntAct:EBI-361605 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0016544 name: ikbkg-flna physical interaction xref: IntAct:EBI-361608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:I0016545 name: ikbkg-ipo7 physical interaction xref: IntAct:EBI-361611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN [Term] id: CCO:I0016546 name: ikbkg-usp18 physical interaction xref: IntAct:EBI-361617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063074 ! UBP18_HUMAN [Term] id: CCO:I0016547 name: ikbkg-kiaa0219 physical interaction xref: IntAct:EBI-361623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0058073 ! GCN1L_HUMAN [Term] id: CCO:I0016548 name: ikbkg-myh9 physical interaction xref: IntAct:EBI-361626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0016549 name: ikbkg-hnrpu physical interaction xref: IntAct:EBI-361629 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:I0016550 name: ikbkg-atp5b physical interaction xref: IntAct:EBI-361632 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005827 ! ATPB_HUMAN [Term] id: CCO:I0016551 name: ikbkg-tuba8 physical interaction xref: IntAct:EBI-361635 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0024578 ! TBA8_HUMAN [Term] id: CCO:I0016552 name: ikbkg-vim physical interaction xref: IntAct:EBI-361638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016553 name: ikbkg-adprt physical interaction xref: IntAct:EBI-361644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005467 ! PARP1_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0016554 name: ikbkg-slc25a6 physical interaction xref: IntAct:EBI-361647 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0016555 name: ikbkg-copa physical interaction xref: IntAct:EBI-361653 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0038202 ! COPA_HUMAN [Term] id: CCO:I0016556 name: ikbkg-gart physical interaction xref: IntAct:EBI-361662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0021425 ! PUR2_HUMAN [Term] id: CCO:I0016557 name: ikbkg-prkdc physical interaction xref: IntAct:EBI-361665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:I0016558 name: ikbkg-myl6 physical interaction xref: IntAct:EBI-361668 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:I0016559 name: ikbkg-xpo7 physical interaction xref: IntAct:EBI-361674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005665 ! XPO7_HUMAN [Term] id: CCO:I0016560 name: ikbkg-tuba2 physical interaction xref: IntAct:EBI-361677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016561 name: ikbkg-rps3a physical interaction xref: IntAct:EBI-361683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN [Term] id: CCO:I0016562 name: ikbkg-cse1l physical interaction xref: IntAct:EBI-361686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN [Term] id: CCO:I0016563 name: ikbkg-ipo9 physical interaction xref: IntAct:EBI-361689 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063077 ! IPO9_HUMAN [Term] id: CCO:I0016564 name: ikbkg-mlcb physical interaction xref: IntAct:EBI-361698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:I0016565 name: ikbkg-hspd1 physical interaction xref: IntAct:EBI-361701 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN [Term] id: CCO:I0016566 name: ikbkg-rps16 physical interaction xref: IntAct:EBI-361707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063078 ! RS16_HUMAN [Term] id: CCO:I0016567 name: ikbkg-rps27 physical interaction xref: IntAct:EBI-361710 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0016568 name: ikbkg-myo1d physical interaction xref: IntAct:EBI-361713 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063055 ! MYO1D_HUMAN [Term] id: CCO:I0016569 name: ikbkg-tuba1 physical interaction xref: IntAct:EBI-361716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:I0016570 name: tank-hspa1l physical interaction xref: IntAct:EBI-361719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023825 ! HS71L_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016571 name: tank-hspa5 physical interaction xref: IntAct:EBI-361722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016572 name: tank-hspa8 physical interaction xref: IntAct:EBI-361725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016573 name: tank-rars physical interaction xref: IntAct:EBI-361728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058103 ! TANK_HUMAN relationship: has_participant CCO:B0063058 ! SYRC_HUMAN [Term] id: CCO:I0016574 name: tank-hspa9b physical interaction xref: IntAct:EBI-361731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016575 name: tank-iars physical interaction xref: IntAct:EBI-361734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058103 ! TANK_HUMAN relationship: has_participant CCO:B0063045 ! SYIC_HUMAN [Term] id: CCO:I0016576 name: tank-kars physical interaction xref: IntAct:EBI-361737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006279 ! SYK_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016577 name: tank-krt9 physical interaction xref: IntAct:EBI-361740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005922 ! K1C9_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016578 name: tank-nap1l1 physical interaction xref: IntAct:EBI-361746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016579 name: tank-cltc physical interaction xref: IntAct:EBI-361749 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058103 ! TANK_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016580 name: tank-hsp70_1 physical interaction xref: IntAct:EBI-361752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058103 ! TANK_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016581 name: tank-kiaa1352 physical interaction xref: IntAct:EBI-361758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058103 ! TANK_HUMAN relationship: has_participant CCO:B0063072 ! SYLC_HUMAN [Term] id: CCO:I0016582 name: tank-hnrpu physical interaction xref: IntAct:EBI-361761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058103 ! TANK_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:I0016583 name: tank-tbk1 physical interaction xref: IntAct:EBI-361764 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016584 name: tank-krt16 physical interaction xref: IntAct:EBI-361767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023704 ! K1C16_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016585 name: tank-tuba2 physical interaction xref: IntAct:EBI-361770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016586 name: tank-kpnb3 physical interaction xref: IntAct:EBI-361773 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050166 ! IPO5_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016587 name: tank-tank-1 physical interaction xref: IntAct:EBI-361779 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016588 name: tank-krt1 physical interaction xref: IntAct:EBI-361782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005823 ! K2C1_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0016589 name: map3k1-bag2 physical interaction xref: IntAct:EBI-361785 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN [Term] id: CCO:I0016590 name: map3k1-pdcd8 physical interaction xref: IntAct:EBI-361788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0016591 name: map3k1-ywhae physical interaction xref: IntAct:EBI-361791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0016592 name: map3k1-hspa1l physical interaction xref: IntAct:EBI-361794 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016593 name: map3k1-cct8 physical interaction xref: IntAct:EBI-361797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:I0016594 name: map3k1-hspa5 physical interaction xref: IntAct:EBI-361800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016595 name: map3k1-hspa8 physical interaction xref: IntAct:EBI-361803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016596 name: map3k1-slc25a5 physical interaction xref: IntAct:EBI-361809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0016597 name: map3k1-bag5 physical interaction xref: IntAct:EBI-361812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063079 ! BAG5_HUMAN [Term] id: CCO:I0016598 name: map3k1-hspa9b physical interaction xref: IntAct:EBI-361815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016599 name: map3k1-mars physical interaction xref: IntAct:EBI-361818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063060 ! SYMC_HUMAN [Term] id: CCO:I0016600 name: map3k1-rplp2 physical interaction xref: IntAct:EBI-361821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:I0016601 name: map3k1-ruvbl2 physical interaction xref: IntAct:EBI-361824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0016602 name: map3k1-cct5 physical interaction xref: IntAct:EBI-361827 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005291 ! TCPE_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0016603 name: map3k1-eppk1 physical interaction xref: IntAct:EBI-361830 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:I0016604 name: map3k1-map3k1 physical interaction xref: IntAct:EBI-361833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0016605 name: map3k1-hspa6 physical interaction xref: IntAct:EBI-361836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0023839 ! HSP76_HUMAN [Term] id: CCO:I0016606 name: map3k1-dnaja1 physical interaction xref: IntAct:EBI-361839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0016607 name: map3k1-eef1a2 physical interaction xref: IntAct:EBI-361845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0016608 name: map3k1-glud1 physical interaction xref: IntAct:EBI-361848 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:I0016609 name: map3k1-cct1 physical interaction xref: IntAct:EBI-361851 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063080 ! TCPA_HUMAN [Term] id: CCO:I0016610 name: map3k1-ssr4 physical interaction xref: IntAct:EBI-361854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063081 ! SSRD_HUMAN [Term] id: CCO:I0016611 name: map3k1-slc1a5 physical interaction xref: IntAct:EBI-361857 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063082 ! AAAT_HUMAN [Term] id: CCO:I0016612 name: map3k1-cad physical interaction xref: IntAct:EBI-361863 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0016613 name: map3k1-da24a23_2 physical interaction xref: IntAct:EBI-361866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0051815 ! IRS4_HUMAN [Term] id: CCO:I0016614 name: map3k1-actg1 physical interaction xref: IntAct:EBI-361869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016615 name: map3k1-rps6 physical interaction xref: IntAct:EBI-361872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0015901 ! RS6_HUMAN [Term] id: CCO:I0016616 name: map3k1-rpl3 physical interaction xref: IntAct:EBI-361875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063083 ! RL3_HUMAN [Term] id: CCO:I0016617 name: map3k1-hadhb physical interaction xref: IntAct:EBI-361878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063084 ! ECHB_HUMAN [Term] id: CCO:I0016618 name: map3k1-lgals3bp physical interaction xref: IntAct:EBI-361887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0055789 ! LG3BP_HUMAN [Term] id: CCO:I0016619 name: map3k1-rps11 physical interaction xref: IntAct:EBI-361890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063085 ! RS11_HUMAN [Term] id: CCO:I0016620 name: map3k1-rps14 physical interaction xref: IntAct:EBI-361893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:I0016621 name: map3k1-fasn physical interaction xref: IntAct:EBI-361896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:I0016622 name: map3k1-cct3 physical interaction xref: IntAct:EBI-361899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0016623 name: map3k1-cct6a physical interaction xref: IntAct:EBI-361902 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063086 ! TCPZ_HUMAN [Term] id: CCO:I0016624 name: map3k1-gemin4 physical interaction xref: IntAct:EBI-361905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063087 ! GEMI4_HUMAN [Term] id: CCO:I0016625 name: map3k1-rcn2 physical interaction xref: IntAct:EBI-361908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN [Term] id: CCO:I0016626 name: map3k1-rpl35a physical interaction xref: IntAct:EBI-361911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063048 ! RL35A_HUMAN [Term] id: CCO:I0016627 name: map3k1-rpl7 physical interaction xref: IntAct:EBI-361914 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005746 ! RL7_HUMAN [Term] id: CCO:I0016628 name: map3k1-hadha physical interaction xref: IntAct:EBI-361920 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063089 ! ECHA_HUMAN [Term] id: CCO:I0016629 name: map3k1-hsp70_1 physical interaction xref: IntAct:EBI-361923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016630 name: map3k1-q9buf5 physical interaction xref: IntAct:EBI-361926 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0019883 ! TBB6_HUMAN [Term] id: CCO:I0016631 name: map3k1-rpl14 physical interaction xref: IntAct:EBI-361929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063090 ! RL14_HUMAN [Term] id: CCO:I0016632 name: map3k1-q9nzl4 physical interaction xref: IntAct:EBI-361935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005199 ! HPBP1_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0016633 name: map3k1-rps27 physical interaction xref: IntAct:EBI-361947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0016634 name: map3k1-q8nhw5 physical interaction xref: IntAct:EBI-361950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063050 ! RLA0L_HUMAN [Term] id: CCO:I0016635 name: map3k1-dnaja3 physical interaction xref: IntAct:EBI-361953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0016636 name: map3k1-flna physical interaction xref: IntAct:EBI-361956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:I0016637 name: map3k1-dhx9 physical interaction xref: IntAct:EBI-361959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:I0016638 name: map3k1-rpl18 physical interaction xref: IntAct:EBI-361962 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005741 ! RL18_HUMAN [Term] id: CCO:I0016639 name: map3k1-rpl37a physical interaction xref: IntAct:EBI-361965 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0006231 ! RL37A_HUMAN [Term] id: CCO:I0016640 name: map3k1-vim physical interaction xref: IntAct:EBI-361968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016641 name: map3k1-h4f2 physical interaction xref: IntAct:EBI-361974 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005700 ! H4_HUMAN [Term] id: CCO:I0016642 name: map3k1-rps8 physical interaction xref: IntAct:EBI-361977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005734 ! RS8_HUMAN [Term] id: CCO:I0016643 name: map3k1-slc25a6 physical interaction xref: IntAct:EBI-361983 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0016644 name: map3k1-ncl physical interaction xref: IntAct:EBI-361989 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:I0016645 name: map3k1-rps23 physical interaction xref: IntAct:EBI-361992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0030465 ! RS23_HUMAN [Term] id: CCO:I0016646 name: map3k1-rpl35 physical interaction xref: IntAct:EBI-361995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063091 ! RL35_HUMAN [Term] id: CCO:I0016647 name: map3k1-hsph1 physical interaction xref: IntAct:EBI-362001 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:I0016648 name: map3k1-tuba2 physical interaction xref: IntAct:EBI-362004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016649 name: map3k1-rpl13 physical interaction xref: IntAct:EBI-362007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0033633 ! RL13_HUMAN [Term] id: CCO:I0016650 name: map3k1-rpl10 physical interaction xref: IntAct:EBI-362016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063093 ! RL10_HUMAN [Term] id: CCO:I0016651 name: map3k1-rpl24 physical interaction xref: IntAct:EBI-362022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005856 ! RL24_HUMAN [Term] id: CCO:I0016652 name: map3k1-snrpf physical interaction xref: IntAct:EBI-362025 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0043438 ! RUXF_HUMAN [Term] id: CCO:I0016653 name: map3k1-usp9x physical interaction xref: IntAct:EBI-362031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:I0016654 name: map3k1-rps9 physical interaction xref: IntAct:EBI-362034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005750 ! RS9_HUMAN [Term] id: CCO:I0016655 name: map3k1-rps16 physical interaction xref: IntAct:EBI-362037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063078 ! RS16_HUMAN [Term] id: CCO:I0016656 name: map3k1-mylk2 physical interaction xref: IntAct:EBI-362040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0036526 ! MYLK2_HUMAN [Term] id: CCO:I0016657 name: map3k1-myo1d physical interaction xref: IntAct:EBI-362043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063055 ! MYO1D_HUMAN [Term] id: CCO:I0016658 name: map3k1-tuba1 physical interaction xref: IntAct:EBI-362046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:I0016659 name: map3k3-bag2 physical interaction xref: IntAct:EBI-362052 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN [Term] id: CCO:I0016660 name: map3k3-pdcd8 physical interaction xref: IntAct:EBI-362055 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0016661 name: map3k3-q9h6t3 physical interaction xref: IntAct:EBI-362058 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063095 ! RPAP3_HUMAN [Term] id: CCO:I0016662 name: map3k3-ikbkg physical interaction xref: IntAct:EBI-362061 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016663 name: map3k3-scin physical interaction xref: IntAct:EBI-362064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0051620 ! ADSV_HUMAN [Term] id: CCO:I0016664 name: map3k3-hspa1l physical interaction xref: IntAct:EBI-362067 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016665 name: map3k3-hspa4 physical interaction xref: IntAct:EBI-362070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:I0016666 name: map3k3-cct8 physical interaction xref: IntAct:EBI-362073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:I0016667 name: map3k3-gnb2 physical interaction xref: IntAct:EBI-362076 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0055623 ! GBB2_HUMAN [Term] id: CCO:I0016668 name: map3k3-hspa5 physical interaction xref: IntAct:EBI-362079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016669 name: map3k3-dbn1 physical interaction xref: IntAct:EBI-362082 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:I0016670 name: map3k3-dnajb4 physical interaction xref: IntAct:EBI-362085 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0016224 ! DNJB4_HUMAN [Term] id: CCO:I0016671 name: map3k3-tmod3 physical interaction xref: IntAct:EBI-362088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063097 ! TMOD3_HUMAN [Term] id: CCO:I0016672 name: map3k3-chuk physical interaction xref: IntAct:EBI-362091 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0016673 name: map3k3-pfdn6 physical interaction xref: IntAct:EBI-362094 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063098 ! PFD6_HUMAN [Term] id: CCO:I0016674 name: map3k3-ubl4 physical interaction xref: IntAct:EBI-362097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063099 ! UBL4A_HUMAN [Term] id: CCO:I0016675 name: map3k3-capza1 physical interaction xref: IntAct:EBI-362100 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0037567 ! CAZA1_HUMAN [Term] id: CCO:I0016676 name: map3k3-slc25a5 physical interaction xref: IntAct:EBI-362106 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0016677 name: map3k3-bag5 physical interaction xref: IntAct:EBI-362112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063079 ! BAG5_HUMAN [Term] id: CCO:I0016678 name: map3k3-mars physical interaction xref: IntAct:EBI-362115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063060 ! SYMC_HUMAN [Term] id: CCO:I0016679 name: map3k3-coro1c physical interaction xref: IntAct:EBI-362118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0025115 ! COR1C_HUMAN [Term] id: CCO:I0016680 name: map3k3-ruvbl2 physical interaction xref: IntAct:EBI-362121 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016681 name: map3k3-iqgap1 physical interaction xref: IntAct:EBI-362127 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:I0016682 name: map3k3-rpl23 physical interaction xref: IntAct:EBI-362130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:I0016683 name: map3k3-myo1c physical interaction xref: IntAct:EBI-362133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063063 ! MYO1C_HUMAN [Term] id: CCO:I0016684 name: map3k3-hs1bp1 physical interaction xref: IntAct:EBI-362136 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0062934 ! HAX1_HUMAN [Term] id: CCO:I0016685 name: map3k3-cct5 physical interaction xref: IntAct:EBI-362139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005291 ! TCPE_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016686 name: map3k3-eppk1 physical interaction xref: IntAct:EBI-362142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:I0016687 name: map3k3-phgdh physical interaction xref: IntAct:EBI-362145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063100 ! SERA_HUMAN [Term] id: CCO:I0016688 name: map3k3-hspa6 physical interaction xref: IntAct:EBI-362151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0023839 ! HSP76_HUMAN [Term] id: CCO:I0016689 name: map3k3-dnaja1 physical interaction xref: IntAct:EBI-362154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0016690 name: map3k3-iars physical interaction xref: IntAct:EBI-362157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063045 ! SYIC_HUMAN [Term] id: CCO:I0016691 name: map3k3-hnrph1 physical interaction xref: IntAct:EBI-362166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:I0016692 name: map3k3-myo1b physical interaction xref: IntAct:EBI-362169 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063101 ! MYO1B_HUMAN [Term] id: CCO:I0016693 name: map3k3-c1qbp physical interaction xref: IntAct:EBI-362172 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0016694 name: map3k3-eef1a2 physical interaction xref: IntAct:EBI-362175 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0016695 name: map3k3-sco2 physical interaction xref: IntAct:EBI-362178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063102 ! SCO2_HUMAN [Term] id: CCO:I0016696 name: map3k3-sptan1 physical interaction xref: IntAct:EBI-362181 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0016697 name: map3k3-pfdn4 physical interaction xref: IntAct:EBI-362184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063103 ! PFD4_HUMAN [Term] id: CCO:I0016698 name: map3k3-dnajb1 physical interaction xref: IntAct:EBI-362187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0016220 ! DNJB1_HUMAN [Term] id: CCO:I0016699 name: map3k3-atp5a1 physical interaction xref: IntAct:EBI-362190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:I0016700 name: map3k3-matr3 physical interaction xref: IntAct:EBI-362193 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:I0016701 name: map3k3-cct1 physical interaction xref: IntAct:EBI-362196 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063080 ! TCPA_HUMAN [Term] id: CCO:I0016702 name: map3k3-tfg physical interaction xref: IntAct:EBI-362202 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:I0016703 name: map3k3-cad physical interaction xref: IntAct:EBI-362208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0016704 name: map3k3-actg1 physical interaction xref: IntAct:EBI-362214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016705 name: map3k3-rmp physical interaction xref: IntAct:EBI-362217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0054697 ! RMP_HUMAN [Term] id: CCO:I0016706 name: map3k3-vcp physical interaction xref: IntAct:EBI-362220 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:I0016707 name: map3k3-q92600 physical interaction xref: IntAct:EBI-362223 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0058069 ! RCD1_HUMAN [Term] id: CCO:I0016708 name: map3k3-cltc physical interaction xref: IntAct:EBI-362229 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016709 name: map3k3-ikbkb physical interaction xref: IntAct:EBI-362232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016710 name: map3k3-ppp2r1b physical interaction xref: IntAct:EBI-362238 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005517 ! 2AAB_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016711 name: map3k3-gnai2 physical interaction xref: IntAct:EBI-362241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN [Term] id: CCO:I0016712 name: map3k3-capzb physical interaction xref: IntAct:EBI-362244 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0006125 ! CAPZB_HUMAN [Term] id: CCO:I0016713 name: map3k3-gnb1 physical interaction xref: IntAct:EBI-362247 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0055621 ! GBB1_HUMAN [Term] id: CCO:I0016714 name: map3k3-fasn physical interaction xref: IntAct:EBI-362250 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:I0016715 name: map3k3-cct3 physical interaction xref: IntAct:EBI-362253 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016716 name: map3k3-xpot physical interaction xref: IntAct:EBI-362256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005664 ! XPOT_HUMAN [Term] id: CCO:I0016717 name: map3k3-plod physical interaction xref: IntAct:EBI-362259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063104 ! PLOD1_HUMAN [Term] id: CCO:I0016718 name: map3k3-cct6a physical interaction xref: IntAct:EBI-362265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063086 ! TCPZ_HUMAN [Term] id: CCO:I0016719 name: map3k3-mm_1 physical interaction xref: IntAct:EBI-362268 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063105 ! Q9C083_HUMAN [Term] id: CCO:I0016720 name: map3k3-st13 physical interaction xref: IntAct:EBI-362274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063106 ! F10A1_HUMAN [Term] id: CCO:I0016721 name: map3k3-hsp70_1 physical interaction xref: IntAct:EBI-362277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016722 name: map3k3-q9buf5 physical interaction xref: IntAct:EBI-362280 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0019883 ! TBB6_HUMAN [Term] id: CCO:I0016723 name: map3k3-hspa8 physical interaction xref: IntAct:EBI-362283 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016724 name: map3k3-myo6 physical interaction xref: IntAct:EBI-362292 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:I0016725 name: map3k3-uba52-1 physical interaction xref: IntAct:EBI-362298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063107 ! RL40_HUMAN [Term] id: CCO:I0016726 name: map3k3-q969i2 physical interaction xref: IntAct:EBI-362301 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0034185 ! Q969I2_HUMAN [Term] id: CCO:I0016727 name: map3k3-s100a8 physical interaction xref: IntAct:EBI-362304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0006159 ! S10A8_HUMAN [Term] id: CCO:I0016728 name: map3k3-q9nws0 physical interaction xref: IntAct:EBI-362310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063108 ! PIHD1_HUMAN [Term] id: CCO:I0016729 name: map3k3-q9bv68 physical interaction xref: IntAct:EBI-362322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0043418 ! RN126_HUMAN [Term] id: CCO:I0016730 name: map3k3-q96lm8 physical interaction xref: IntAct:EBI-362325 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063109 ! Q96LM8_HUMAN [Term] id: CCO:I0016731 name: map3k3-dkfzp761m0817 physical interaction xref: IntAct:EBI-362331 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:I0016732 name: map3k3-q8n532 physical interaction xref: IntAct:EBI-362337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063110 ! Q8N532_HUMAN [Term] id: CCO:I0016733 name: map3k3-kiaa0147 physical interaction xref: IntAct:EBI-362340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063111 ! LAP4_HUMAN [Term] id: CCO:I0016734 name: map3k3-uxt physical interaction xref: IntAct:EBI-362343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063112 ! UXT_HUMAN [Term] id: CCO:I0016735 name: map3k3-q9bzf9 physical interaction xref: IntAct:EBI-362346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063038 ! UACA_HUMAN [Term] id: CCO:I0016736 name: map3k3-alk physical interaction xref: IntAct:EBI-362352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:I0016737 name: map3k3-dnaja3 physical interaction xref: IntAct:EBI-362358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0016738 name: map3k3-map3k2 physical interaction xref: IntAct:EBI-362364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0059318 ! M3K2_HUMAN [Term] id: CCO:I0016739 name: map3k3-flna physical interaction xref: IntAct:EBI-362367 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:I0016740 name: map3k3-map3k3 physical interaction xref: IntAct:EBI-362370 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016741 name: map3k3-ppp1r12a physical interaction xref: IntAct:EBI-362373 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063113 ! MYPT1_HUMAN [Term] id: CCO:I0016742 name: map3k3-myh9 physical interaction xref: IntAct:EBI-362376 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0016743 name: map3k3-lyn physical interaction xref: IntAct:EBI-362379 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016744 name: map3k3-q8taq2 physical interaction xref: IntAct:EBI-362385 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016745 name: map3k3-vbp1 physical interaction xref: IntAct:EBI-362388 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0038197 ! PFD3_HUMAN [Term] id: CCO:I0016746 name: map3k3-vim physical interaction xref: IntAct:EBI-362391 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016747 name: map3k3-h4f2 physical interaction xref: IntAct:EBI-362394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005700 ! H4_HUMAN [Term] id: CCO:I0016748 name: map3k3-sptbn1 physical interaction xref: IntAct:EBI-362397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0016749 name: map3k3-slc25a6 physical interaction xref: IntAct:EBI-362400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0016750 name: map3k3-q8n8k8 physical interaction xref: IntAct:EBI-362403 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063114 ! Q8N8K8_HUMAN [Term] id: CCO:I0016751 name: map3k3-q8izp2 physical interaction xref: IntAct:EBI-362406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063115 ! F10A4_HUMAN [Term] id: CCO:I0016752 name: map3k3-pygm physical interaction xref: IntAct:EBI-362409 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063116 ! PYGM_HUMAN [Term] id: CCO:I0016753 name: map3k3-tuba2 physical interaction xref: IntAct:EBI-362415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016754 name: map3k3-dkfzp434k0435 physical interaction xref: IntAct:EBI-362418 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063117 ! Q9UFQ0_HUMAN [Term] id: CCO:I0016755 name: map3k3-prkdc physical interaction xref: IntAct:EBI-362421 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:I0016756 name: map3k3-myl6 physical interaction xref: IntAct:EBI-362424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:I0016757 name: map3k3-gapd physical interaction xref: IntAct:EBI-362433 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0016758 name: map3k3-lgals7 physical interaction xref: IntAct:EBI-362436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063118 ! LEG7_HUMAN [Term] id: CCO:I0016759 name: map3k3-kiaa0310 physical interaction xref: IntAct:EBI-362439 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063119 ! SC16A_HUMAN [Term] id: CCO:I0016760 name: map3k3-s100a7 physical interaction xref: IntAct:EBI-362442 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0051700 ! S10A7_HUMAN [Term] id: CCO:I0016761 name: map3k3-cfl2 physical interaction xref: IntAct:EBI-362445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0033309 ! COF2_HUMAN [Term] id: CCO:I0016762 name: map3k3-nakap95 physical interaction xref: IntAct:EBI-362448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0018469 ! AKP8L_HUMAN [Term] id: CCO:I0016763 name: map3k3-cpvl physical interaction xref: IntAct:EBI-362451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0038468 ! CPVL_HUMAN [Term] id: CCO:I0016764 name: map3k3-dnajc7 physical interaction xref: IntAct:EBI-362454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063120 ! DNJC7_HUMAN [Term] id: CCO:I0016765 name: map3k3-myo1a physical interaction xref: IntAct:EBI-362463 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063121 ! MYO1A_HUMAN [Term] id: CCO:I0016766 name: map3k3-mlcb physical interaction xref: IntAct:EBI-362472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:I0016767 name: map3k3-gnai3 physical interaction xref: IntAct:EBI-362475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0030269 ! GNAI3_HUMAN [Term] id: CCO:I0016768 name: map3k3-iqgap2 physical interaction xref: IntAct:EBI-362478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0018391 ! IQGA2_HUMAN [Term] id: CCO:I0016769 name: map3k3-rps16 physical interaction xref: IntAct:EBI-362481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063078 ! RS16_HUMAN [Term] id: CCO:I0016770 name: map3k3-rps27 physical interaction xref: IntAct:EBI-362484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0016771 name: map3k3-mylk2 physical interaction xref: IntAct:EBI-362487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0036526 ! MYLK2_HUMAN [Term] id: CCO:I0016772 name: map3k3-myo1d physical interaction xref: IntAct:EBI-362490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063055 ! MYO1D_HUMAN [Term] id: CCO:I0016773 name: map3k3-tuba1 physical interaction xref: IntAct:EBI-362493 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:I0016774 name: nfkb2-pdcd8 physical interaction xref: IntAct:EBI-362688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0016775 name: nfkb2-hspa1l-1 physical interaction xref: IntAct:EBI-362692 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016776 name: nfkb2-hspa5-1 physical interaction xref: IntAct:EBI-362695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016777 name: nfkb2-snrp116 physical interaction xref: IntAct:EBI-362698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063122 ! U5S1_HUMAN [Term] id: CCO:I0016778 name: nfkb2-hspa8-1 physical interaction xref: IntAct:EBI-362701 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016779 name: nfkb2-rars physical interaction xref: IntAct:EBI-362704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063058 ! SYRC_HUMAN [Term] id: CCO:I0016780 name: nfkb2-q12905 physical interaction xref: IntAct:EBI-362710 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0055855 ! ILF2_HUMAN [Term] id: CCO:I0016781 name: nfkb2-hspa9b-1 physical interaction xref: IntAct:EBI-362713 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016782 name: nfkb2-mars physical interaction xref: IntAct:EBI-362719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063060 ! SYMC_HUMAN [Term] id: CCO:I0016783 name: nfkb2-rps5 physical interaction xref: IntAct:EBI-362722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063061 ! RS5_HUMAN [Term] id: CCO:I0016784 name: nfkb2-rps10 physical interaction xref: IntAct:EBI-362725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005749 ! RS10_HUMAN [Term] id: CCO:I0016785 name: nfkb2-rplp2 physical interaction xref: IntAct:EBI-362728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:I0016786 name: nfkb2-iqgap1 physical interaction xref: IntAct:EBI-362731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:I0016787 name: nfkb2-nfkbie physical interaction xref: IntAct:EBI-362734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:I0016788 name: nfkb2-rps3 physical interaction xref: IntAct:EBI-362737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:I0016789 name: nfkb2-polrmt physical interaction xref: IntAct:EBI-362740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063040 ! RPOM_HUMAN [Term] id: CCO:I0016790 name: nfkb2-dnaja1 physical interaction xref: IntAct:EBI-362743 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0016791 name: nfkb2-iars-1 physical interaction xref: IntAct:EBI-362746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063045 ! SYIC_HUMAN [Term] id: CCO:I0016792 name: nfkb2-rps18 physical interaction xref: IntAct:EBI-362749 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005763 ! RS18_HUMAN [Term] id: CCO:I0016793 name: nfkb2-eprs physical interaction xref: IntAct:EBI-362752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:I0016794 name: nfkb2-pabpc1 physical interaction xref: IntAct:EBI-362755 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005854 ! PABP1_HUMAN [Term] id: CCO:I0016795 name: nfkb2-eef1a2-1 physical interaction xref: IntAct:EBI-362758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0016796 name: nfkb2-ddx21 physical interaction xref: IntAct:EBI-362761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005805 ! DDX21_HUMAN [Term] id: CCO:I0016797 name: nfkb2-matr3 physical interaction xref: IntAct:EBI-362764 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005968 ! MATR3_HUMAN [Term] id: CCO:I0016798 name: nfkb2-dap3 physical interaction xref: IntAct:EBI-362767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0055464 ! RT29_HUMAN [Term] id: CCO:I0016799 name: nfkb2-cad-1 physical interaction xref: IntAct:EBI-362770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0016800 name: nfkb2-hadhb physical interaction xref: IntAct:EBI-362773 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063084 ! ECHB_HUMAN [Term] id: CCO:I0016801 name: nfkb2-cltc-1 physical interaction xref: IntAct:EBI-362779 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016802 name: nfkb2-ikbkb physical interaction xref: IntAct:EBI-362782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0016803 name: nfkb2-rps11 physical interaction xref: IntAct:EBI-362785 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063085 ! RS11_HUMAN [Term] id: CCO:I0016804 name: nfkb2-rps14 physical interaction xref: IntAct:EBI-362788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:I0016805 name: nfkb2-fasn physical interaction xref: IntAct:EBI-362791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0062802 ! FAS_HUMAN [Term] id: CCO:I0016806 name: nfkb2-gemin4 physical interaction xref: IntAct:EBI-362794 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063087 ! GEMI4_HUMAN [Term] id: CCO:I0016807 name: nfkb2-rpl7 physical interaction xref: IntAct:EBI-362797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005746 ! RL7_HUMAN [Term] id: CCO:I0016808 name: nfkb2-hadha physical interaction xref: IntAct:EBI-362800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063089 ! ECHA_HUMAN [Term] id: CCO:I0016809 name: nfkb2-hsp70_1-1 physical interaction xref: IntAct:EBI-362803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016810 name: nfkb2-q9buf5 physical interaction xref: IntAct:EBI-362806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0019883 ! TBB6_HUMAN [Term] id: CCO:I0016811 name: nfkb2-lkp physical interaction xref: IntAct:EBI-362815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063123 ! Q12803_HUMAN [Term] id: CCO:I0016812 name: nfkb2-a_951c1a1 physical interaction xref: IntAct:EBI-362818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:I0016813 name: nfkb2-nfkb2-1 physical interaction xref: IntAct:EBI-362824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0016814 name: nfkb2-dkfzp761m0817 physical interaction xref: IntAct:EBI-362827 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:I0016815 name: nfkb2-q8nhw5 physical interaction xref: IntAct:EBI-362830 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063050 ! RLA0L_HUMAN [Term] id: CCO:I0016816 name: nfkb2-dnaja3 physical interaction xref: IntAct:EBI-362833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0016817 name: nfkb2-hnrpu physical interaction xref: IntAct:EBI-362836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:I0016818 name: nfkb2-dhx9 physical interaction xref: IntAct:EBI-362839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:I0016819 name: nfkb2-rpl18 physical interaction xref: IntAct:EBI-362842 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005741 ! RL18_HUMAN [Term] id: CCO:I0016820 name: nfkb2-rps19 physical interaction xref: IntAct:EBI-362845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005744 ! RS19_HUMAN [Term] id: CCO:I0016821 name: nfkb2-rps8 physical interaction xref: IntAct:EBI-362851 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005734 ! RS8_HUMAN [Term] id: CCO:I0016822 name: nfkb2-hnrpc physical interaction xref: IntAct:EBI-362854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005239 ! HNRPC_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0016823 name: nfkb2-sfpq physical interaction xref: IntAct:EBI-362857 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0016824 name: nfkb2-adprt physical interaction xref: IntAct:EBI-362860 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005467 ! PARP1_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0016825 name: nfkb2-hspca-1 physical interaction xref: IntAct:EBI-362866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016826 name: nfkb2-ncl physical interaction xref: IntAct:EBI-362869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005733 ! NUCL_HUMAN [Term] id: CCO:I0016827 name: nfkb2-prkdc physical interaction xref: IntAct:EBI-362872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:I0016828 name: nfkb2-tuba2-1 physical interaction xref: IntAct:EBI-362875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016829 name: nfkb2-rpl7a physical interaction xref: IntAct:EBI-362878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005761 ! RL7A_HUMAN [Term] id: CCO:I0016830 name: nfkb2-rps3a physical interaction xref: IntAct:EBI-362884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN [Term] id: CCO:I0016831 name: nfkb2-rpl13 physical interaction xref: IntAct:EBI-362887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0033633 ! RL13_HUMAN [Term] id: CCO:I0016832 name: nfkb2-rps24 physical interaction xref: IntAct:EBI-362893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005726 ! RS24_HUMAN [Term] id: CCO:I0016833 name: nfkb2-hist1h2bb physical interaction xref: IntAct:EBI-362896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:I0016834 name: nfkb2-xrcc5 physical interaction xref: IntAct:EBI-362899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0016835 name: nfkb2-usp9x physical interaction xref: IntAct:EBI-362902 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:I0016836 name: nfkb2-rps16 physical interaction xref: IntAct:EBI-362908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063078 ! RS16_HUMAN [Term] id: CCO:I0016837 name: nfkb2-rps27 physical interaction xref: IntAct:EBI-362911 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0016838 name: nfkb2-tuba1 physical interaction xref: IntAct:EBI-362914 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005772 ! TBA1A_HUMAN [Term] id: CCO:I0016839 name: map3k14-q12905 physical interaction xref: IntAct:EBI-362938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0055855 ! ILF2_HUMAN [Term] id: CCO:I0016840 name: map3k14-hspa9b physical interaction xref: IntAct:EBI-362941 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016841 name: map3k14-ruvbl2 physical interaction xref: IntAct:EBI-362959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0016842 name: map3k14-traf3 physical interaction xref: IntAct:EBI-362968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN [Term] id: CCO:I0016843 name: map3k14-pabpc1 physical interaction xref: IntAct:EBI-362995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005854 ! PABP1_HUMAN [Term] id: CCO:I0016844 name: map3k14-atp5a1 physical interaction xref: IntAct:EBI-363004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:I0016845 name: map3k14-glud1 physical interaction xref: IntAct:EBI-363007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0054824 ! DHE3_HUMAN [Term] id: CCO:I0016846 name: map3k14-nsep1 physical interaction xref: IntAct:EBI-363055 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005742 ! YBOX1_HUMAN [Term] id: CCO:I0016847 name: map3k14-rap1b physical interaction xref: IntAct:EBI-363061 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0024410 ! RAP1B_HUMAN [Term] id: CCO:I0016848 name: map3k14-sfpq physical interaction xref: IntAct:EBI-363109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0016849 name: map3k14-csda physical interaction xref: IntAct:EBI-363136 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0049892 ! DBPA_HUMAN [Term] id: CCO:I0016850 name: map3k14-rps3a physical interaction xref: IntAct:EBI-363157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN [Term] id: CCO:I0016851 name: relb-kpnb1 physical interaction xref: IntAct:EBI-363445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016852 name: relb-kpna1 physical interaction xref: IntAct:EBI-363448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0020532 ! IMA1_HUMAN [Term] id: CCO:I0016853 name: relb-hspa1l physical interaction xref: IntAct:EBI-363451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016854 name: relb-hspa5 physical interaction xref: IntAct:EBI-363454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016855 name: relb-hspa8 physical interaction xref: IntAct:EBI-363457 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016856 name: relb-usp7 physical interaction xref: IntAct:EBI-363460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005429 ! UBP7_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016857 name: relb-chuk physical interaction xref: IntAct:EBI-363463 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0016858 name: relb-hspa9b physical interaction xref: IntAct:EBI-363466 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016859 name: relb-rps5 physical interaction xref: IntAct:EBI-363469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063061 ! RS5_HUMAN [Term] id: CCO:I0016860 name: relb-rps10 physical interaction xref: IntAct:EBI-363472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005749 ! RS10_HUMAN [Term] id: CCO:I0016861 name: relb-rplp2 physical interaction xref: IntAct:EBI-363475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005864 ! RLA2_HUMAN [Term] id: CCO:I0016862 name: relb-nfkbie physical interaction xref: IntAct:EBI-363478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005538 ! IKBE_HUMAN [Term] id: CCO:I0016863 name: relb-hspa6 physical interaction xref: IntAct:EBI-363481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0023839 ! HSP76_HUMAN [Term] id: CCO:I0016864 name: relb-o43809 physical interaction xref: IntAct:EBI-363484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0062837 ! CPSF5_HUMAN [Term] id: CCO:I0016865 name: relb-eprs physical interaction xref: IntAct:EBI-363487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:I0016866 name: relb-c1qbp physical interaction xref: IntAct:EBI-363490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0016867 name: relb-nfkbia physical interaction xref: IntAct:EBI-363493 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016868 name: relb-hsd17b4 physical interaction xref: IntAct:EBI-363496 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063125 ! DHB4_HUMAN [Term] id: CCO:I0016869 name: relb-cad physical interaction xref: IntAct:EBI-363499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0016870 name: relb-actg1 physical interaction xref: IntAct:EBI-363505 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016871 name: relb-cltc physical interaction xref: IntAct:EBI-363511 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016872 name: relb-rps11 physical interaction xref: IntAct:EBI-363514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063085 ! RS11_HUMAN [Term] id: CCO:I0016873 name: relb-rps14 physical interaction xref: IntAct:EBI-363517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:I0016874 name: relb-hpbrii_4 physical interaction xref: IntAct:EBI-363520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063126 ! CPSF6_HUMAN [Term] id: CCO:I0016875 name: relb-hsp70_1 physical interaction xref: IntAct:EBI-363523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016876 name: relb-nono physical interaction xref: IntAct:EBI-363532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016877 name: relb-baf60b physical interaction xref: IntAct:EBI-363541 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005419 ! SMRD2_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016878 name: relb-nfkb2 physical interaction xref: IntAct:EBI-363547 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016879 name: relb-dkfzp761m0817 physical interaction xref: IntAct:EBI-363550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:I0016880 name: relb-q8nhw5 physical interaction xref: IntAct:EBI-363553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063050 ! RLA0L_HUMAN [Term] id: CCO:I0016881 name: relb-q96ta9 physical interaction xref: IntAct:EBI-363556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063127 ! Q96TA9_HUMAN [Term] id: CCO:I0016882 name: relb-hnrpu physical interaction xref: IntAct:EBI-363562 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063051 ! HNRPU_HUMAN [Term] id: CCO:I0016883 name: relb-sfpq physical interaction xref: IntAct:EBI-363568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0016884 name: relb-dsp physical interaction xref: IntAct:EBI-363571 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0042506 ! DESP_HUMAN [Term] id: CCO:I0016885 name: relb-prkdc physical interaction xref: IntAct:EBI-363574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:I0016886 name: relb-tuba2 physical interaction xref: IntAct:EBI-363577 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016887 name: relb-nqo2 physical interaction xref: IntAct:EBI-363580 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063128 ! NQO2_HUMAN [Term] id: CCO:I0016888 name: relb-ddx1 physical interaction xref: IntAct:EBI-363586 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0058058 ! DDX1_HUMAN [Term] id: CCO:I0016889 name: relb-usp9x physical interaction xref: IntAct:EBI-363589 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063094 ! USP9X_HUMAN [Term] id: CCO:I0016890 name: relb-relb physical interaction xref: IntAct:EBI-363592 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016891 name: relb-smarcd1 physical interaction xref: IntAct:EBI-363595 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0016892 name: ripk1-hspa1l physical interaction xref: IntAct:EBI-363598 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016893 name: ripk1-hspa5 physical interaction xref: IntAct:EBI-363601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016894 name: ripk1-hspa8 physical interaction xref: IntAct:EBI-363604 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016895 name: ripk1-slc25a5 physical interaction xref: IntAct:EBI-363607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0016896 name: ripk1-hspa9b physical interaction xref: IntAct:EBI-363610 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016897 name: ripk1-rpl23 physical interaction xref: IntAct:EBI-363613 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:I0016898 name: ripk1-dnaja1 physical interaction xref: IntAct:EBI-363616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0016899 name: ripk1-ripk1 physical interaction xref: IntAct:EBI-363619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:I0016900 name: ripk1-cad physical interaction xref: IntAct:EBI-363622 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0016901 name: ripk1-actg1 physical interaction xref: IntAct:EBI-363625 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016902 name: ripk1-rcn2 physical interaction xref: IntAct:EBI-363631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN [Term] id: CCO:I0016903 name: ripk1-hsp70_1 physical interaction xref: IntAct:EBI-363634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016904 name: ripk1-hspca physical interaction xref: IntAct:EBI-363643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016905 name: ripk1-tuba2 physical interaction xref: IntAct:EBI-363646 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016906 name: ripk2-hspa1l physical interaction xref: IntAct:EBI-363652 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016907 name: ripk2-hspa8 physical interaction xref: IntAct:EBI-363655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016908 name: ripk2-hspa6 physical interaction xref: IntAct:EBI-363661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0023839 ! HSP76_HUMAN [Term] id: CCO:I0016909 name: ripk2-actg1 physical interaction xref: IntAct:EBI-363667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016910 name: ripk2-ripk2 physical interaction xref: IntAct:EBI-363670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN [Term] id: CCO:I0016911 name: ripk2-hadhb physical interaction xref: IntAct:EBI-363673 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0063084 ! ECHB_HUMAN [Term] id: CCO:I0016912 name: ripk2-gemin4 physical interaction xref: IntAct:EBI-363676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0063087 ! GEMI4_HUMAN [Term] id: CCO:I0016913 name: ripk2-hsp70_1 physical interaction xref: IntAct:EBI-363682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016914 name: ripk2-myh9 physical interaction xref: IntAct:EBI-363694 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0016915 name: ripk2-eno1 physical interaction xref: IntAct:EBI-363697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005779 ! ENOA_HUMAN [Term] id: CCO:I0016916 name: ripk2-vim physical interaction xref: IntAct:EBI-363700 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0016917 name: ripk2-hspca physical interaction xref: IntAct:EBI-363703 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016918 name: ripk2-gapd physical interaction xref: IntAct:EBI-363706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005458 ! G3P_HUMAN [Term] id: CCO:I0016919 name: ripk2-tuba2 physical interaction xref: IntAct:EBI-363709 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016920 name: ripk2-myo1d physical interaction xref: IntAct:EBI-363712 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0063055 ! MYO1D_HUMAN [Term] id: CCO:I0016921 name: map3k7ip1-hspa1l physical interaction xref: IntAct:EBI-363964 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016922 name: map3k7ip1-hspa4 physical interaction xref: IntAct:EBI-363967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:I0016923 name: map3k7ip1-hspa5 physical interaction xref: IntAct:EBI-363970 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016924 name: map3k7ip1-hspa8 physical interaction xref: IntAct:EBI-363973 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016925 name: map3k7ip1-hspa9b physical interaction xref: IntAct:EBI-363976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016926 name: map3k7ip1-hspa6 physical interaction xref: IntAct:EBI-363979 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0023839 ! HSP76_HUMAN [Term] id: CCO:I0016927 name: map3k7ip1-dnaja1 physical interaction xref: IntAct:EBI-363982 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0016928 name: map3k7ip1-map3k7ip1 physical interaction xref: IntAct:EBI-363985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN [Term] id: CCO:I0016929 name: map3k7ip1-osp94 physical interaction xref: IntAct:EBI-363994 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0063129 ! HS74L_HUMAN [Term] id: CCO:I0016930 name: map3k7ip1-hsp70_1 physical interaction xref: IntAct:EBI-363997 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016931 name: map3k7ip1-irak1 physical interaction xref: IntAct:EBI-364009 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:I0016932 name: map3k7ip1-hspca physical interaction xref: IntAct:EBI-364012 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016933 name: map3k7ip1-tuba2 physical interaction xref: IntAct:EBI-364018 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016934 name: map3k7ip1-dnajc7 physical interaction xref: IntAct:EBI-364021 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0063120 ! DNJC7_HUMAN [Term] id: CCO:I0016935 name: q9nyj8-bag2 physical interaction xref: IntAct:EBI-364027 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN [Term] id: CCO:I0016936 name: q9nyj8-ywhae physical interaction xref: IntAct:EBI-364030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:I0016937 name: q9nyj8-hspa5 physical interaction xref: IntAct:EBI-364033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016938 name: q9nyj8-hspa8 physical interaction xref: IntAct:EBI-364036 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016939 name: q9nyj8-hspa9b physical interaction xref: IntAct:EBI-364042 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016940 name: q9nyj8-ruvbl2 physical interaction xref: IntAct:EBI-364045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:I0016941 name: q9nyj8-rpl23 physical interaction xref: IntAct:EBI-364048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:I0016942 name: q9nyj8-dnaja1 physical interaction xref: IntAct:EBI-364051 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0016943 name: q9nyj8-hnrph1 physical interaction xref: IntAct:EBI-364054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005732 ! HNRH1_HUMAN [Term] id: CCO:I0016944 name: q9nyj8-c1qbp physical interaction xref: IntAct:EBI-364057 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0016945 name: q9nyj8-eef1a2 physical interaction xref: IntAct:EBI-364060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0016946 name: q9nyj8-sptan1 physical interaction xref: IntAct:EBI-364063 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0016947 name: q9nyj8-cad physical interaction xref: IntAct:EBI-364066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0016948 name: q9nyj8-actg1 physical interaction xref: IntAct:EBI-364072 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0016949 name: q9nyj8-lgals3bp physical interaction xref: IntAct:EBI-364078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0055789 ! LG3BP_HUMAN [Term] id: CCO:I0016950 name: q9nyj8-cltc physical interaction xref: IntAct:EBI-364081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0016951 name: q9nyj8-sec13l1 physical interaction xref: IntAct:EBI-364084 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005452 ! SEC13_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:I0016952 name: q9nyj8-hsp70_1 physical interaction xref: IntAct:EBI-364087 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016953 name: q9nyj8-dkfzp761m0817 physical interaction xref: IntAct:EBI-364105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:I0016954 name: q9nyj8-flna physical interaction xref: IntAct:EBI-364108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:I0016955 name: q9nyj8-hspca physical interaction xref: IntAct:EBI-364114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0016956 name: q9nyj8-tuba2 physical interaction xref: IntAct:EBI-364120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016957 name: q9nyj8-rps27 physical interaction xref: IntAct:EBI-364123 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0016958 name: tbk1-cct8 physical interaction xref: IntAct:EBI-364213 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0032388 ! TCPQ_HUMAN [Term] id: CCO:I0016959 name: tbk1-hspa5 physical interaction xref: IntAct:EBI-364216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016960 name: tbk1-hspa8 physical interaction xref: IntAct:EBI-364219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016961 name: tbk1-hspa9b physical interaction xref: IntAct:EBI-364222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016962 name: tbk1-rps5 physical interaction xref: IntAct:EBI-364225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0063061 ! RS5_HUMAN [Term] id: CCO:I0016963 name: tbk1-ruvbl2 physical interaction xref: IntAct:EBI-364228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0016964 name: tbk1-cct5 physical interaction xref: IntAct:EBI-364231 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005291 ! TCPE_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0016965 name: tbk1-rps18 physical interaction xref: IntAct:EBI-364234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005763 ! RS18_HUMAN [Term] id: CCO:I0016966 name: tbk1-atp5a1 physical interaction xref: IntAct:EBI-364237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:I0016967 name: tbk1-cct1 physical interaction xref: IntAct:EBI-364240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0063080 ! TCPA_HUMAN [Term] id: CCO:I0016968 name: tbk1-lgals3bp physical interaction xref: IntAct:EBI-364252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0055789 ! LG3BP_HUMAN [Term] id: CCO:I0016969 name: tbk1-cct3 physical interaction xref: IntAct:EBI-364258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0016970 name: tbk1-cct6a physical interaction xref: IntAct:EBI-364261 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0063086 ! TCPZ_HUMAN [Term] id: CCO:I0016971 name: tbk1-rpl7 physical interaction xref: IntAct:EBI-364264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005746 ! RL7_HUMAN [Term] id: CCO:I0016972 name: tbk1-hsp70_1 physical interaction xref: IntAct:EBI-364267 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0016973 name: tbk1-nono physical interaction xref: IntAct:EBI-364273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0016974 name: tbk1-q8nhw5 physical interaction xref: IntAct:EBI-364282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0063050 ! RLA0L_HUMAN [Term] id: CCO:I0016975 name: tbk1-rps8 physical interaction xref: IntAct:EBI-364288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005734 ! RS8_HUMAN [Term] id: CCO:I0016976 name: tbk1-sfpq physical interaction xref: IntAct:EBI-364291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0016977 name: tbk1-tbk1 physical interaction xref: IntAct:EBI-364294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0016978 name: tbk1-gapd physical interaction xref: IntAct:EBI-364297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0016979 name: tbk1-tuba2 physical interaction xref: IntAct:EBI-364300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0016980 name: tbk1-rpl13 physical interaction xref: IntAct:EBI-364306 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0033633 ! RL13_HUMAN [Term] id: CCO:I0016981 name: tbk1-ldhb physical interaction xref: IntAct:EBI-364309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0063130 ! LDHB_HUMAN [Term] id: CCO:I0016982 name: tnfrsf1a-bag2 physical interaction xref: IntAct:EBI-364321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN [Term] id: CCO:I0016983 name: tnfrsf1a-afg3l2 physical interaction xref: IntAct:EBI-364324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0025289 ! AFG32_HUMAN [Term] id: CCO:I0016984 name: tnfrsf1a-sel1l physical interaction xref: IntAct:EBI-364327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0059086 ! SE1L1_HUMAN [Term] id: CCO:I0016985 name: tnfrsf1a-hspa1l physical interaction xref: IntAct:EBI-364330 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0016986 name: tnfrsf1a-hspa5 physical interaction xref: IntAct:EBI-364333 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0016987 name: tnfrsf1a-hspa8 physical interaction xref: IntAct:EBI-364336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0016988 name: tnfrsf1a-rars physical interaction xref: IntAct:EBI-364339 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063058 ! SYRC_HUMAN [Term] id: CCO:I0016989 name: tnfrsf1a-atp1a1 physical interaction xref: IntAct:EBI-364342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005459 ! AT1A1_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0016990 name: tnfrsf1a-slc25a5 physical interaction xref: IntAct:EBI-364345 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0016991 name: tnfrsf1a-ipo8 physical interaction xref: IntAct:EBI-364348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0050581 ! IPO8_HUMAN [Term] id: CCO:I0016992 name: tnfrsf1a-hspa9b physical interaction xref: IntAct:EBI-364351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0016993 name: tnfrsf1a-rpl23 physical interaction xref: IntAct:EBI-364354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:I0016994 name: tnfrsf1a-hs1bp1 physical interaction xref: IntAct:EBI-364357 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0062934 ! HAX1_HUMAN [Term] id: CCO:I0016995 name: tnfrsf1a-eppk1 physical interaction xref: IntAct:EBI-364360 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0050501 ! EPIPL_HUMAN [Term] id: CCO:I0016996 name: tnfrsf1a-rps3 physical interaction xref: IntAct:EBI-364363 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:I0016997 name: tnfrsf1a-hspa6 physical interaction xref: IntAct:EBI-364366 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0023839 ! HSP76_HUMAN [Term] id: CCO:I0016998 name: tnfrsf1a-dnaja1 physical interaction xref: IntAct:EBI-364369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0016999 name: tnfrsf1a-c1qbp physical interaction xref: IntAct:EBI-364375 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0017000 name: tnfrsf1a-dnajb12 physical interaction xref: IntAct:EBI-364378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0037130 ! DJB12_HUMAN [Term] id: CCO:I0017001 name: tnfrsf1a-atp5a1 physical interaction xref: IntAct:EBI-364381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:I0017002 name: tnfrsf1a-tnfrsf1a physical interaction xref: IntAct:EBI-364384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0017003 name: tnfrsf1a-ssr4 physical interaction xref: IntAct:EBI-364387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063081 ! SSRD_HUMAN [Term] id: CCO:I0017004 name: tnfrsf1a-slc1a5 physical interaction xref: IntAct:EBI-364390 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063082 ! AAAT_HUMAN [Term] id: CCO:I0017005 name: tnfrsf1a-cad physical interaction xref: IntAct:EBI-364396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0017006 name: tnfrsf1a-canx physical interaction xref: IntAct:EBI-364399 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063067 ! CALX_HUMAN [Term] id: CCO:I0017007 name: tnfrsf1a-actg1 physical interaction xref: IntAct:EBI-364405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0017008 name: tnfrsf1a-slc25a3 physical interaction xref: IntAct:EBI-364408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005847 ! MPCP_HUMAN [Term] id: CCO:I0017009 name: tnfrsf1a-cltcl1 physical interaction xref: IntAct:EBI-364411 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005460 ! CLH2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0017010 name: tnfrsf1a-cdipt physical interaction xref: IntAct:EBI-364417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0027593 ! CDIPT_HUMAN [Term] id: CCO:I0017011 name: tnfrsf1a-nap1l1 physical interaction xref: IntAct:EBI-364420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0017012 name: tnfrsf1a-cltc physical interaction xref: IntAct:EBI-364423 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0017013 name: tnfrsf1a-ddost physical interaction xref: IntAct:EBI-364426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063131 ! OST48_HUMAN [Term] id: CCO:I0017014 name: tnfrsf1a-xpot physical interaction xref: IntAct:EBI-364429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005664 ! XPOT_HUMAN [Term] id: CCO:I0017015 name: tnfrsf1a-rcn2 physical interaction xref: IntAct:EBI-364432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN [Term] id: CCO:I0017016 name: tnfrsf1a-hadha physical interaction xref: IntAct:EBI-364438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063089 ! ECHA_HUMAN [Term] id: CCO:I0017017 name: tnfrsf1a-hsp70_1 physical interaction xref: IntAct:EBI-364441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0017018 name: tnfrsf1a-q9buf5 physical interaction xref: IntAct:EBI-364444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0019883 ! TBB6_HUMAN [Term] id: CCO:I0017019 name: tnfrsf1a-myo6 physical interaction xref: IntAct:EBI-364456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:I0017020 name: tnfrsf1a-uba52 physical interaction xref: IntAct:EBI-364462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063107 ! RL40_HUMAN [Term] id: CCO:I0017021 name: tnfrsf1a-q96ag4 physical interaction xref: IntAct:EBI-364474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005845 ! LRC59_HUMAN [Term] id: CCO:I0017022 name: tnfrsf1a-rps27 physical interaction xref: IntAct:EBI-364477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0017023 name: tnfrsf1a-dnaja3 physical interaction xref: IntAct:EBI-364486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0017024 name: tnfrsf1a-kiaa0219 physical interaction xref: IntAct:EBI-364492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0058073 ! GCN1L_HUMAN [Term] id: CCO:I0017025 name: tnfrsf1a-myh9 physical interaction xref: IntAct:EBI-364495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0017026 name: tnfrsf1a-hist3h3 physical interaction xref: IntAct:EBI-364501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063017 ! H31T_HUMAN [Term] id: CCO:I0017027 name: tnfrsf1a-h4f2 physical interaction xref: IntAct:EBI-364504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005700 ! H4_HUMAN [Term] id: CCO:I0017028 name: tnfrsf1a-slc25a6 physical interaction xref: IntAct:EBI-364507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0017029 name: tnfrsf1a-sec61a1 physical interaction xref: IntAct:EBI-364510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0027154 ! S61A1_HUMAN [Term] id: CCO:I0017030 name: tnfrsf1a-prkdc physical interaction xref: IntAct:EBI-364513 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:I0017031 name: tnfrsf1a-myl6 physical interaction xref: IntAct:EBI-364516 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005743 ! MYL6_HUMAN [Term] id: CCO:I0017032 name: tnfrsf1a-tuba2 physical interaction xref: IntAct:EBI-364519 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0017033 name: tnfrsf1a-atp2a2 physical interaction xref: IntAct:EBI-364522 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:I0017034 name: tnfrsf1a-hist1h2bb physical interaction xref: IntAct:EBI-364528 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063124 ! H2B1B_HUMAN [Term] id: CCO:I0017035 name: tnfrsf1a-mlcb physical interaction xref: IntAct:EBI-364531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:I0017036 name: tnfrsf1a-rps16 physical interaction xref: IntAct:EBI-364534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0063078 ! RS16_HUMAN [Term] id: CCO:I0017037 name: tnfrsf1b-pdcd8 physical interaction xref: IntAct:EBI-364540 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0017038 name: tnfrsf1b-ipo8 physical interaction xref: IntAct:EBI-364567 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0050581 ! IPO8_HUMAN [Term] id: CCO:I0017039 name: tnfrsf1b-hspa9b physical interaction xref: IntAct:EBI-364570 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0017040 name: tnfrsf1b-q9p035 physical interaction xref: IntAct:EBI-364573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0059026 ! PTAD1_HUMAN [Term] id: CCO:I0017041 name: tnfrsf1b-eef1a2 physical interaction xref: IntAct:EBI-364618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0017042 name: tnfrsf1b-atp5a1 physical interaction xref: IntAct:EBI-364624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN [Term] id: CCO:I0017043 name: tnfrsf1b-da24a23_2 physical interaction xref: IntAct:EBI-364642 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0051815 ! IRS4_HUMAN [Term] id: CCO:I0017044 name: tnfrsf1b-gbf1 physical interaction xref: IntAct:EBI-364648 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005359 ! GBF1_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0017045 name: tnfrsf1b-rps14 physical interaction xref: IntAct:EBI-364675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:I0017046 name: tnfrsf1b-myo6 physical interaction xref: IntAct:EBI-364705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:I0017047 name: tnfrsf1b-dnaja3 physical interaction xref: IntAct:EBI-364726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0017048 name: tnfrsf1b-flna physical interaction xref: IntAct:EBI-364729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:I0017049 name: tnfrsf1b-ipo7 physical interaction xref: IntAct:EBI-364732 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN [Term] id: CCO:I0017050 name: tnfrsf1b-kiaa0219 physical interaction xref: IntAct:EBI-364741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0058073 ! GCN1L_HUMAN [Term] id: CCO:I0017051 name: tnfrsf1b-tra1 physical interaction xref: IntAct:EBI-364744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0055025 ! ENPL_HUMAN [Term] id: CCO:I0017052 name: tnfrsf1b-myh9 physical interaction xref: IntAct:EBI-364747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0017053 name: tnfrsf1b-atp2a2 physical interaction xref: IntAct:EBI-364789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:I0017054 name: tnfrsf1b-cse1l physical interaction xref: IntAct:EBI-364798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN [Term] id: CCO:I0017055 name: tnfrsf1b-rps27 physical interaction xref: IntAct:EBI-364807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0017056 name: tnfrsf1b-mylk2 physical interaction xref: IntAct:EBI-364810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0036526 ! MYLK2_HUMAN [Term] id: CCO:I0017057 name: tradd-pdcd8 physical interaction xref: IntAct:EBI-364813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0017058 name: tradd-kpnb1 physical interaction xref: IntAct:EBI-364816 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0017059 name: tradd-hspa1l physical interaction xref: IntAct:EBI-364819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0017060 name: tradd-hspa8 physical interaction xref: IntAct:EBI-364822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0017061 name: tradd-atp1a1 physical interaction xref: IntAct:EBI-364825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005459 ! AT1A1_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0017062 name: tradd-slc25a5 physical interaction xref: IntAct:EBI-364828 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0017063 name: tradd-ipo8 physical interaction xref: IntAct:EBI-364831 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0050581 ! IPO8_HUMAN [Term] id: CCO:I0017064 name: tradd-rps3 physical interaction xref: IntAct:EBI-364834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:I0017065 name: tradd-dnaja1 physical interaction xref: IntAct:EBI-364837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0017066 name: tradd-c1qbp physical interaction xref: IntAct:EBI-364840 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0017067 name: tradd-eef1a2 physical interaction xref: IntAct:EBI-364843 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0017068 name: tradd-tradd physical interaction xref: IntAct:EBI-364846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0017069 name: tradd-cad physical interaction xref: IntAct:EBI-364849 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0017070 name: tradd-actg1 physical interaction xref: IntAct:EBI-364852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0017071 name: tradd-slc25a3 physical interaction xref: IntAct:EBI-364855 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005847 ! MPCP_HUMAN [Term] id: CCO:I0017072 name: tradd-lgals3bp physical interaction xref: IntAct:EBI-364858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0055789 ! LG3BP_HUMAN [Term] id: CCO:I0017073 name: tradd-nap1l1 physical interaction xref: IntAct:EBI-364861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0017074 name: tradd-cltc physical interaction xref: IntAct:EBI-364864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0017075 name: tradd-rcn2 physical interaction xref: IntAct:EBI-364867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN [Term] id: CCO:I0017076 name: tradd-hsp70_1 physical interaction xref: IntAct:EBI-364870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0017077 name: tradd-dkfzp761m0817 physical interaction xref: IntAct:EBI-364882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:I0017078 name: tradd-ipo7 physical interaction xref: IntAct:EBI-364888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005661 ! IPO7_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0017079 name: tradd-vim physical interaction xref: IntAct:EBI-364891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0017080 name: tradd-slc25a6 physical interaction xref: IntAct:EBI-364897 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0017081 name: tradd-hspca physical interaction xref: IntAct:EBI-364900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017082 name: tradd-prkdc physical interaction xref: IntAct:EBI-364903 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0063076 ! PRKDC_HUMAN [Term] id: CCO:I0017083 name: tradd-tuba2 physical interaction xref: IntAct:EBI-364906 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0017084 name: tradd-atp2a2 physical interaction xref: IntAct:EBI-364909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:I0017085 name: tradd-rps16 physical interaction xref: IntAct:EBI-364915 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0063078 ! RS16_HUMAN [Term] id: CCO:I0017086 name: tradd-rps27 physical interaction xref: IntAct:EBI-364918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN [Term] id: CCO:I0017087 name: traf1-bag2 physical interaction xref: IntAct:EBI-364921 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN [Term] id: CCO:I0017088 name: traf1-hspa1l physical interaction xref: IntAct:EBI-364924 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0017089 name: traf1-hspa8 physical interaction xref: IntAct:EBI-364927 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017090 name: traf1-slc25a5 physical interaction xref: IntAct:EBI-364930 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005813 ! ADT2_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017091 name: traf1-hspa9b physical interaction xref: IntAct:EBI-364933 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017092 name: traf1-rps3 physical interaction xref: IntAct:EBI-364936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0030969 ! RS3_HUMAN [Term] id: CCO:I0017093 name: traf1-traf1 physical interaction xref: IntAct:EBI-364939 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017094 name: traf1-dnaja1 physical interaction xref: IntAct:EBI-364942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017095 name: traf1-c1qbp physical interaction xref: IntAct:EBI-364945 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0063035 ! C1QBP_HUMAN [Term] id: CCO:I0017096 name: traf1-ddx5 physical interaction xref: IntAct:EBI-364948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005729 ! DDX5_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017097 name: traf1-actg1 physical interaction xref: IntAct:EBI-364951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0017098 name: traf1-nap1l1 physical interaction xref: IntAct:EBI-364957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017099 name: traf1-anp32a physical interaction xref: IntAct:EBI-364960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0006073 ! AN32A_HUMAN [Term] id: CCO:I0017100 name: traf1-rcn2 physical interaction xref: IntAct:EBI-364963 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN [Term] id: CCO:I0017101 name: traf1-hsp70_1 physical interaction xref: IntAct:EBI-364966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0017102 name: traf1-q96gx9 physical interaction xref: IntAct:EBI-364972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0042018 ! APIP_HUMAN [Term] id: CCO:I0017103 name: traf1-nono physical interaction xref: IntAct:EBI-364975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017104 name: traf1-ppib physical interaction xref: IntAct:EBI-364978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0006327 ! PPIB_HUMAN [Term] id: CCO:I0017105 name: traf1-ighg1 physical interaction xref: IntAct:EBI-364984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN [Term] id: CCO:I0017106 name: traf1-ddx3x physical interaction xref: IntAct:EBI-364990 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005773 ! DDX3X_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017107 name: traf1-sfpq physical interaction xref: IntAct:EBI-364996 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0017108 name: traf1-hspca physical interaction xref: IntAct:EBI-364999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017109 name: traf1-gapd physical interaction xref: IntAct:EBI-365002 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005458 ! G3P_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017110 name: traf1-tuba2 physical interaction xref: IntAct:EBI-365005 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0017111 name: traf2-bag2 physical interaction xref: IntAct:EBI-365008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0063043 ! BAG2_HUMAN [Term] id: CCO:I0017112 name: traf2-hspa1l physical interaction xref: IntAct:EBI-365011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0017113 name: traf2-hspa4 physical interaction xref: IntAct:EBI-365014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0063096 ! HSP74_HUMAN [Term] id: CCO:I0017114 name: traf2-hspa5 physical interaction xref: IntAct:EBI-365017 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0017115 name: traf2-hspa8 physical interaction xref: IntAct:EBI-365020 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0017116 name: traf2-slc25a5 physical interaction xref: IntAct:EBI-365023 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005813 ! ADT2_HUMAN [Term] id: CCO:I0017117 name: traf2-hspa9b physical interaction xref: IntAct:EBI-365026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0017118 name: traf2-ruvbl2 physical interaction xref: IntAct:EBI-365029 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN [Term] id: CCO:I0017119 name: traf2-rpl23 physical interaction xref: IntAct:EBI-365032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0043592 ! RL23_HUMAN [Term] id: CCO:I0017120 name: traf2-dnaja1 physical interaction xref: IntAct:EBI-365035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0017121 name: traf2-eef1a2 physical interaction xref: IntAct:EBI-365038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0017122 name: traf2-cad physical interaction xref: IntAct:EBI-365041 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0063066 ! PYR1_HUMAN [Term] id: CCO:I0017123 name: traf2-actg1 physical interaction xref: IntAct:EBI-365047 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0017124 name: traf2-nap1l1 physical interaction xref: IntAct:EBI-365050 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0017125 name: traf2-cltc physical interaction xref: IntAct:EBI-365053 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0062997 ! CLH1_HUMAN [Term] id: CCO:I0017126 name: traf2-traf2 physical interaction xref: IntAct:EBI-365059 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0017127 name: traf2-hsp70_1 physical interaction xref: IntAct:EBI-365065 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0017128 name: traf2-q96gx9 physical interaction xref: IntAct:EBI-365074 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0042018 ! APIP_HUMAN [Term] id: CCO:I0017129 name: traf2-adprt physical interaction xref: IntAct:EBI-365089 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0017130 name: traf2-hspca physical interaction xref: IntAct:EBI-365092 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017131 name: traf2-tuba2 physical interaction xref: IntAct:EBI-365095 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0017132 name: traf2-mylk2 physical interaction xref: IntAct:EBI-365104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0036526 ! MYLK2_HUMAN [Term] id: CCO:I0017133 name: traf6-kpnb1 physical interaction xref: IntAct:EBI-365110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0017134 name: traf6-hspa1l physical interaction xref: IntAct:EBI-365113 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0023825 ! HS71L_HUMAN [Term] id: CCO:I0017135 name: traf6-hspa5 physical interaction xref: IntAct:EBI-365116 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0017136 name: traf6-hspa8 physical interaction xref: IntAct:EBI-365119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN [Term] id: CCO:I0017137 name: traf6-hspa9b physical interaction xref: IntAct:EBI-365122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0017138 name: traf6-o75477 physical interaction xref: IntAct:EBI-365125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0063132 ! ERLN1_HUMAN [Term] id: CCO:I0017139 name: traf6-dnaja1 physical interaction xref: IntAct:EBI-365134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN [Term] id: CCO:I0017140 name: traf6-eef1a2 physical interaction xref: IntAct:EBI-365140 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN [Term] id: CCO:I0017141 name: traf6-actg1 physical interaction xref: IntAct:EBI-365146 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0017142 name: traf6-vcp physical interaction xref: IntAct:EBI-365155 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:I0017143 name: traf6-rcn2 physical interaction xref: IntAct:EBI-365164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0063088 ! RCN2_HUMAN [Term] id: CCO:I0017144 name: traf6-hadha physical interaction xref: IntAct:EBI-365170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0063089 ! ECHA_HUMAN [Term] id: CCO:I0017145 name: traf6-hsp70_1 physical interaction xref: IntAct:EBI-365173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0063037 ! Q9UQC1_HUMAN [Term] id: CCO:I0017146 name: traf6-q9buf5 physical interaction xref: IntAct:EBI-365176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0019883 ! TBB6_HUMAN [Term] id: CCO:I0017147 name: traf6-bri3bp physical interaction xref: IntAct:EBI-365188 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0063133 ! BRI3B_HUMAN [Term] id: CCO:I0017148 name: traf6-psmd11 physical interaction xref: IntAct:EBI-365191 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0017149 name: traf6-q9bv68 physical interaction xref: IntAct:EBI-365197 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0043418 ! RN126_HUMAN [Term] id: CCO:I0017150 name: traf6-ipo7 physical interaction xref: IntAct:EBI-365203 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN [Term] id: CCO:I0017151 name: traf6-adprt physical interaction xref: IntAct:EBI-365209 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005467 ! PARP1_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0017152 name: traf6-tuba2 physical interaction xref: IntAct:EBI-365215 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0017153 name: traf6-atp2a2 physical interaction xref: IntAct:EBI-365218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005840 ! AT2A2_HUMAN [Term] id: CCO:I0017154 name: map3k8-nfkb1 physical interaction xref: IntAct:EBI-365224 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0017155 name: rel-flip1 physical interaction xref: IntAct:EBI-365233 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037117 ! TNIP2_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0017156 name: rel-map3k8 physical interaction xref: IntAct:EBI-365237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0017157 name: rel-papola physical interaction xref: IntAct:EBI-365241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0063134 ! PAPOA_HUMAN [Term] id: CCO:I0017158 name: nfkbia-fbxw1b-1 physical interaction xref: IntAct:EBI-365247 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005941 ! FBW1B_HUMAN [Term] id: CCO:I0017159 name: nfkbia-rel physical interaction xref: IntAct:EBI-365250 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0017160 name: nfkbia-nfkbib physical interaction xref: IntAct:EBI-365256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0017161 name: nfkbia-ikbkap physical interaction xref: IntAct:EBI-365259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005521 ! IKBA_HUMAN [Term] id: CCO:I0017162 name: nfkbia-chuk physical interaction xref: IntAct:EBI-365262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017163 name: nfkbia-ikbkb physical interaction xref: IntAct:EBI-365265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0017164 name: nfkbia-ikbkg physical interaction xref: IntAct:EBI-365268 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0017165 name: nfkbib-ase_1 physical interaction xref: IntAct:EBI-365286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0054437 ! RPA34_HUMAN [Term] id: CCO:I0017166 name: nfkbib-fbxw1b physical interaction xref: IntAct:EBI-365289 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005941 ! FBW1B_HUMAN [Term] id: CCO:I0017167 name: nfkbib-rel physical interaction xref: IntAct:EBI-365292 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0017168 name: nfkbib-chuk physical interaction xref: IntAct:EBI-365298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017169 name: nfkbib-ikbkb physical interaction xref: IntAct:EBI-365301 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0017170 name: nfkbib-ikbkg physical interaction xref: IntAct:EBI-365304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0017171 name: nfkbib-iqgap2 physical interaction xref: IntAct:EBI-365307 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0018391 ! IQGA2_HUMAN [Term] id: CCO:I0017172 name: nfkbib-lrpprc physical interaction xref: IntAct:EBI-365313 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005755 ! LPPRC_HUMAN [Term] id: CCO:I0017173 name: nfkbib-mtif2 physical interaction xref: IntAct:EBI-365319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0023063 ! IF2M_HUMAN [Term] id: CCO:I0017174 name: nfkbib-nfkb1 physical interaction xref: IntAct:EBI-365322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0017175 name: nfkbib-rasal2 physical interaction xref: IntAct:EBI-365328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0019350 ! NGAP_HUMAN [Term] id: CCO:I0017176 name: nfkbib-q9gzs1 physical interaction xref: IntAct:EBI-365331 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063135 ! RPA49_HUMAN [Term] id: CCO:I0017177 name: nfkbib-pdcd2 physical interaction xref: IntAct:EBI-365334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063136 ! PDCD2_HUMAN [Term] id: CCO:I0017178 name: nfkbib-polr1a physical interaction xref: IntAct:EBI-365337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063137 ! RPA1_HUMAN [Term] id: CCO:I0017179 name: nfkbib-polr1b-1 physical interaction xref: IntAct:EBI-365340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0049472 ! Q9BSR4_HUMAN [Term] id: CCO:I0017180 name: nfkbib-polr1d physical interaction xref: IntAct:EBI-365343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0021709 ! RPAC2_HUMAN [Term] id: CCO:I0017181 name: nfkbib-polr2h physical interaction xref: IntAct:EBI-365346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0063138 ! RPAB3_HUMAN [Term] id: CCO:I0017182 name: nfkbib-polr2l physical interaction xref: IntAct:EBI-365349 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0055622 ! RPAB5_HUMAN [Term] id: CCO:I0017183 name: nfkbib-polr1c physical interaction xref: IntAct:EBI-365355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005246 ! RPAC1_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0017184 name: nfkbie-fbxw1b physical interaction xref: IntAct:EBI-365361 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0005941 ! FBW1B_HUMAN [Term] id: CCO:I0017185 name: nfkbie-rel physical interaction xref: IntAct:EBI-365364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0017186 name: nfkbie-chuk physical interaction xref: IntAct:EBI-365373 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005538 ! IKBE_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017187 name: nfkb2-flip1 physical interaction xref: IntAct:EBI-365410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0037117 ! TNIP2_HUMAN [Term] id: CCO:I0017188 name: nfkb2-map3k8 physical interaction xref: IntAct:EBI-365413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005520 ! M3K8_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0017189 name: nfkb2-rel-1 physical interaction xref: IntAct:EBI-365416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN [Term] id: CCO:I0017190 name: nfkb2-ddx3x physical interaction xref: IntAct:EBI-365419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005773 ! DDX3X_HUMAN [Term] id: CCO:I0017191 name: nfkb2-glg1 physical interaction xref: IntAct:EBI-365422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0063139 ! GSLG1_HUMAN [Term] id: CCO:I0017192 name: nfkb2-gtf2i physical interaction xref: IntAct:EBI-365425 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:I0017193 name: nfkb2-nfkbia-1 physical interaction xref: IntAct:EBI-365428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0017194 name: nfkb2-nfkbib-1 physical interaction xref: IntAct:EBI-365431 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN [Term] id: CCO:I0017195 name: nfkb2-chuk-1 physical interaction xref: IntAct:EBI-365434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017196 name: nfkb2-ikbkg-2 physical interaction xref: IntAct:EBI-365437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN [Term] id: CCO:I0017197 name: nfkb2-nfkb1-1 physical interaction xref: IntAct:EBI-365440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0017198 name: nfkb2-relb-1 physical interaction xref: IntAct:EBI-365449 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0017199 name: nfkb2-rpl6 physical interaction xref: IntAct:EBI-365455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0055717 ! RL6_HUMAN [Term] id: CCO:I0017200 name: nfkb2-rps13 physical interaction xref: IntAct:EBI-365458 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005748 ! RS13_HUMAN [Term] id: CCO:I0017201 name: map3k14-hspca physical interaction xref: IntAct:EBI-365467 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017202 name: traf1-traf2 physical interaction xref: IntAct:EBI-365470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017203 name: traf6-kcnq1 physical interaction xref: IntAct:EBI-365473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0049421 ! KCNQ1_HUMAN [Term] id: CCO:I0017204 name: traf6-psmd13 physical interaction xref: IntAct:EBI-365497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0030887 ! PSD13_HUMAN [Term] id: CCO:I0017205 name: chuk-fkbp5 physical interaction xref: IntAct:EBI-365527 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0063039 ! FKBP5_HUMAN [Term] id: CCO:I0017206 name: chuk-hspca physical interaction xref: IntAct:EBI-365530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017207 name: chuk-hspcb physical interaction xref: IntAct:EBI-365533 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017208 name: chuk-ikbkb physical interaction xref: IntAct:EBI-365536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017209 name: ikbkb-hspca physical interaction xref: IntAct:EBI-365542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017210 name: ikbkb-hspcb physical interaction xref: IntAct:EBI-365545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017211 name: ikbkb-dkfzp761m0817 physical interaction xref: IntAct:EBI-365548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0038243 ! K1967_HUMAN [Term] id: CCO:I0017212 name: ikbke-fkbp5 physical interaction xref: IntAct:EBI-365554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0063039 ! FKBP5_HUMAN [Term] id: CCO:I0017213 name: ikbke-hspca physical interaction xref: IntAct:EBI-365557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017214 name: ikbke-hspcb physical interaction xref: IntAct:EBI-365560 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017215 name: ikbke-ktn1 physical interaction xref: IntAct:EBI-365563 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0063140 ! KTN1_HUMAN [Term] id: CCO:I0017216 name: ikbkg-q9nwg8 physical interaction xref: IntAct:EBI-365572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0063141 ! Q9NWG8_HUMAN [Term] id: CCO:I0017217 name: ikbkg-hspca physical interaction xref: IntAct:EBI-365575 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017218 name: ikbkg-hspcb physical interaction xref: IntAct:EBI-365578 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017219 name: ikbkg-chuk physical interaction xref: IntAct:EBI-365581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017220 name: ikbkg-ikbkb physical interaction xref: IntAct:EBI-365584 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0017221 name: ikbkg-il14 physical interaction xref: IntAct:EBI-365587 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0055326 ! TXLNA_HUMAN [Term] id: CCO:I0017222 name: ikbkg-tbk1 physical interaction xref: IntAct:EBI-365590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0017223 name: tank-traf2 physical interaction xref: IntAct:EBI-365593 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0017224 name: tank-traf3 physical interaction xref: IntAct:EBI-365596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0017225 name: map3k1-fkbp5 physical interaction xref: IntAct:EBI-365602 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0063039 ! FKBP5_HUMAN [Term] id: CCO:I0017226 name: map3k1-han11 physical interaction xref: IntAct:EBI-365605 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0024681 ! WDR68_HUMAN [Term] id: CCO:I0017227 name: map3k1-hspca physical interaction xref: IntAct:EBI-365608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017228 name: map3k1-hspcb physical interaction xref: IntAct:EBI-365611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017229 name: map3k1-rpl4 physical interaction xref: IntAct:EBI-365617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005861 ! RL4_HUMAN [Term] id: CCO:I0017230 name: map3k1-rps13 physical interaction xref: IntAct:EBI-365620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005748 ! RS13_HUMAN [Term] id: CCO:I0017231 name: map3k3-ywhaz physical interaction xref: IntAct:EBI-365623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0017232 name: map3k3-ywhab physical interaction xref: IntAct:EBI-365626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0017233 name: map3k3-ywhae physical interaction xref: IntAct:EBI-365629 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0017234 name: map3k3-ywhah physical interaction xref: IntAct:EBI-365632 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0017235 name: map3k3-ywhag physical interaction xref: IntAct:EBI-365635 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005489 ! 1433G_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN [Term] id: CCO:I0017236 name: map3k3-c20orf126 physical interaction xref: IntAct:EBI-365641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0063142 ! PDRG1_HUMAN [Term] id: CCO:I0017237 name: map3k3-hspa9b physical interaction xref: IntAct:EBI-365647 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN [Term] id: CCO:I0017238 name: map3k3-hspca physical interaction xref: IntAct:EBI-365650 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017239 name: map3k3-hspcb physical interaction xref: IntAct:EBI-365653 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017240 name: map3k3-map2k5 physical interaction xref: IntAct:EBI-365659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0050242 ! MP2K5_HUMAN [Term] id: CCO:I0017241 name: map3k3-pfdn2 physical interaction xref: IntAct:EBI-365662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0029133 ! PFD2_HUMAN [Term] id: CCO:I0017242 name: map3k14-hspcb physical interaction xref: IntAct:EBI-365665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017243 name: map3k14-chuk physical interaction xref: IntAct:EBI-365668 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017244 name: map3k14-ikbkb physical interaction xref: IntAct:EBI-365671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0017245 name: map3k14-ikbkg physical interaction xref: IntAct:EBI-365674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN [Term] id: CCO:I0017246 name: map3k14-rpl6 physical interaction xref: IntAct:EBI-365683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0055717 ! RL6_HUMAN [Term] id: CCO:I0017247 name: relb-kpna6 physical interaction xref: IntAct:EBI-365719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0020529 ! IMA7_HUMAN [Term] id: CCO:I0017248 name: relb-nfkb1 physical interaction xref: IntAct:EBI-365722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0017249 name: relb-dpf2 physical interaction xref: IntAct:EBI-365731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0058094 ! REQU_HUMAN [Term] id: CCO:I0017250 name: relb-smarca4 physical interaction xref: IntAct:EBI-365734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0017251 name: relb-baf155 physical interaction xref: IntAct:EBI-365737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0017252 name: relb-q8taq2 physical interaction xref: IntAct:EBI-365740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN [Term] id: CCO:I0017253 name: relb-q9h836 physical interaction xref: IntAct:EBI-365746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0019996 ! Q9H836_HUMAN [Term] id: CCO:I0017254 name: relb-usp11 physical interaction xref: IntAct:EBI-365749 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0063143 ! UBP11_HUMAN [Term] id: CCO:I0017255 name: map3k7ip1-traf2 physical interaction xref: IntAct:EBI-365752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005531 ! TAB1_HUMAN [Term] id: CCO:I0017256 name: q9nyj8-map3k7ip1 physical interaction xref: IntAct:EBI-365758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN [Term] id: CCO:I0017257 name: tbk1-hspca physical interaction xref: IntAct:EBI-365785 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0017258 name: tbk1-hspcb physical interaction xref: IntAct:EBI-365788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN [Term] id: CCO:I0017259 name: tbk1-tank-1 physical interaction xref: IntAct:EBI-365791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0017260 name: tbk1-tilp physical interaction xref: IntAct:EBI-365797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0063144 ! AZI2_HUMAN [Term] id: CCO:I0017261 name: tbk1-traf2 physical interaction xref: IntAct:EBI-365800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN [Term] id: CCO:I0017262 name: tnfrsf1b-traf2 physical interaction xref: IntAct:EBI-365818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0017263 name: tradd-traf2 physical interaction xref: IntAct:EBI-365821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0017264 name: bdnf-ntf3-1 direct interaction xref: IntAct:EBI-1026019 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0032721 ! BDNF_HUMAN relationship: has_participant CCO:B0055124 ! NTF3_HUMAN [Term] id: CCO:I0017265 name: cd80-ctla4-1 direct interaction comment: Human b7-1-ctla-4 co-stimulatory complex xref: IntAct:EBI-1031055 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055268 ! CD80_HUMAN relationship: has_participant CCO:B0063145 ! CTLA4_HUMAN [Term] id: CCO:I0017266 name: il10-il10ra-1 direct interaction comment: Human il-10 / il-10r1 complex xref: IntAct:EBI-1031672 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055142 ! IL10_HUMAN relationship: has_participant CCO:B0063146 ! I10R1_HUMAN [Term] id: CCO:I0017267 name: arhgap1-rhoa-1 direct interaction comment: Crystal structure of rhoa.gdp.mgf3-in complex with rhogap xref: IntAct:EBI-1033210 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN [Term] id: CCO:I0017268 name: akt2-gsk3b-1 direct interaction comment: Structure of activated form of pkb kinase domain s474d with gsk3 peptide and amp-pnp xref: IntAct:EBI-1034879 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005910 ! AKT2_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:I0017269 name: akt2-gsk3b-2 direct interaction comment: Crystal structure of an activated akt-protein kinase b (pkb-pif chimera) ternary complex with amp-pnp and gsk3 peptide xref: IntAct:EBI-1034890 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005910 ! AKT2_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:I0017270 name: fga-fgb-2 physical interaction comment: Crystal structure of fragment d of bbetad398a fibrinogen xref: IntAct:EBI-1038131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054865 ! FIBA_HUMAN relationship: has_participant CCO:B0054866 ! FIBB_HUMAN relationship: has_participant CCO:B0054867 ! FIBG_HUMAN [Term] id: CCO:I0017271 name: itga2b-itgb3-2 direct interaction comment: Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen xref: IntAct:EBI-1040341 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0017272 name: nucleolin-myh9-1 physical interaction comment: Interaction between human Nucleolin and MYH9 detected by mass spectrometry xref: IntAct:EBI-1166818 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0017273 name: ar-myst2-1 physical interaction comment: In a yeast two-hybrid assay the human androgen receptor interacts with HBO1 (MYST2) xref: IntAct:EBI-1179537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0017274 name: pak2-pak2-3 phosphorylation comment: Trans-autophosphorylation of PAK2 xref: IntAct:EBI-1182895 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:I0017275 name: pak2-limk1-2 phosphorylation comment: Phosphorylation of LIMK1 by PAK2 xref: IntAct:EBI-1187058 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN relationship: has_participant CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:I0017276 name: pak2-raf1-2 phosphorylation comment: Phosphorylation of RAF1 by PAK1 xref: IntAct:EBI-1187075 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:I0017277 name: eif4g-pabp1 physical interaction comment: Recognition of eIF4G by Rotavirus NSP3 reveals a basis for mRNA circularization xref: IntAct:EBI-296459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0017278 name: nrcam-hspa12a-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-296986 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015672 ! NRCAM_HUMAN relationship: has_participant CCO:B0063147 ! HS12A_HUMAN [Term] id: CCO:I0017279 name: hoxb1-pbx1-1 direct interaction comment: Interaction detected by X-ray crystallography. xref: IntAct:EBI-297969 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055028 ! HXB1_HUMAN relationship: has_participant CCO:B0055329 ! PBX1_HUMAN [Term] id: CCO:I0017280 name: nrcam-hspa12a physical interaction xref: IntAct:EBI-311479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015672 ! NRCAM_HUMAN relationship: has_participant CCO:B0063147 ! HS12A_HUMAN [Term] id: CCO:I0017281 name: synj2-itsn2 physical interaction xref: IntAct:EBI-311491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006199 ! ITSN2_HUMAN relationship: has_participant CCO:B0051188 ! SYNJ2_HUMAN [Term] id: CCO:I0017282 name: kiaa0463-kiaa1199 physical interaction xref: IntAct:EBI-311519 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054599 ! PLXA2_HUMAN relationship: has_participant CCO:B0063148 ! K1199_HUMAN [Term] id: CCO:I0017283 name: kiaa0463-pdcd6ip physical interaction xref: IntAct:EBI-311523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054599 ! PLXA2_HUMAN relationship: has_participant CCO:B0063149 ! PDC6I_HUMAN [Term] id: CCO:I0017284 name: kiaa0543-kiaa1043 physical interaction xref: IntAct:EBI-311527 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054541 ! ZN862_HUMAN relationship: has_participant CCO:B0063150 ! TTC28_HUMAN [Term] id: CCO:I0017285 name: kiaa0543-kiaa1218 physical interaction xref: IntAct:EBI-311531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054541 ! ZN862_HUMAN relationship: has_participant CCO:B0063151 ! AT7L1_HUMAN [Term] id: CCO:I0017286 name: kiaa0578-kiaa0440 physical interaction xref: IntAct:EBI-311539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005545 ! NRX1A_HUMAN relationship: has_participant CCO:B0054452 ! SI1L1_HUMAN [Term] id: CCO:I0017287 name: cntnap2-kiaa1224 physical interaction xref: IntAct:EBI-311591 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059135 ! CNTP2_HUMAN relationship: has_participant CCO:B0059227 ! ZMIZ1_HUMAN [Term] id: CCO:I0017288 name: kiaa0911-setdb1 physical interaction xref: IntAct:EBI-311603 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0038991 ! CSTN1_HUMAN [Term] id: CCO:I0017289 name: kiaa0911-mcm3ap physical interaction xref: IntAct:EBI-311611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038991 ! CSTN1_HUMAN relationship: has_participant CCO:B0054547 ! MCM3A_HUMAN [Term] id: CCO:I0017290 name: kiaa0960-ddef2 physical interaction xref: IntAct:EBI-311623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054450 ! DDEF2_HUMAN relationship: has_participant CCO:B0063152 ! THS7A_HUMAN [Term] id: CCO:I0017291 name: epb41l3-kiaa1032 physical interaction xref: IntAct:EBI-311631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059271 ! UN13A_HUMAN relationship: has_participant CCO:B0063153 ! E41L3_HUMAN [Term] id: CCO:I0017292 name: kiaa1206-spock2 physical interaction xref: IntAct:EBI-311655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005547 ! PLXB3_HUMAN relationship: has_participant CCO:B0026671 ! TICN2_HUMAN [Term] id: CCO:I0017293 name: kiaa1206-arhgef11 physical interaction xref: IntAct:EBI-311659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005547 ! PLXB3_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN [Term] id: CCO:I0017294 name: kiaa1206-aip1 physical interaction xref: IntAct:EBI-311663 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005547 ! PLXB3_HUMAN relationship: has_participant CCO:B0063032 ! MAGI2_HUMAN [Term] id: CCO:I0017295 name: kiaa1206-btbd3 physical interaction xref: IntAct:EBI-311671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005547 ! PLXB3_HUMAN relationship: has_participant CCO:B0063154 ! BTBD3_HUMAN [Term] id: CCO:I0017296 name: crsp3-pum2 physical interaction xref: IntAct:EBI-311679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:I0017297 name: crsp3-kiaa0593 physical interaction xref: IntAct:EBI-311683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN [Term] id: CCO:I0017298 name: crsp3-wdtc1 physical interaction xref: IntAct:EBI-311687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0063155 ! WDTC1_HUMAN [Term] id: CCO:I0017299 name: crsp3-kiaa1041 physical interaction xref: IntAct:EBI-311691 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0039141 ! FOXJ3_HUMAN [Term] id: CCO:I0017300 name: sema6a-kiaa0777 physical interaction xref: IntAct:EBI-311707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058685 ! SEM6A_HUMAN relationship: has_participant CCO:B0063156 ! SRBS2_HUMAN [Term] id: CCO:I0017301 name: sema6a-itsn2 physical interaction xref: IntAct:EBI-311711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006199 ! ITSN2_HUMAN relationship: has_participant CCO:B0058685 ! SEM6A_HUMAN [Term] id: CCO:I0017302 name: kiaa1549-itsn2 physical interaction xref: IntAct:EBI-311739 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006199 ! ITSN2_HUMAN relationship: has_participant CCO:B0043861 ! K1549_HUMAN [Term] id: CCO:I0017303 name: megf10-grb10 physical interaction xref: IntAct:EBI-311791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005549 ! MEG10_HUMAN relationship: has_participant CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:I0017304 name: dach-ncor1-2 physical interaction xref: IntAct:EBI-347316 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:I0017305 name: hras-rgl1 physical interaction comment: Interaction of HRas with RGL1 confirmed by GST pull down xref: IntAct:EBI-366044 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN [Term] id: CCO:I0017306 name: rit1-rgl1 physical interaction comment: Interaction between RIT1 and RGL1 confirmed by GST pull-down xref: IntAct:EBI-366052 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN [Term] id: CCO:I0017307 name: rgl1-rit1 physical interaction comment: Interaction of RIT1 with RLG1 confirmed by GST pull-down xref: IntAct:EBI-366064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN [Term] id: CCO:I0017308 name: rlg1-rit2 physical interaction comment: Interaction of RIT2 with RLG1 confirmed by GST pull-down xref: IntAct:EBI-366071 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0058426 ! RIT2_HUMAN [Term] id: CCO:I0017309 name: il7-il2rg-1 physical interaction xref: IntAct:EBI-368456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0055246 ! IL2RG_HUMAN [Term] id: CCO:I0017310 name: ikbkb-ncoa3-2 physical interaction xref: IntAct:EBI-370894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0017311 name: parp1-wrn-1 direct interaction comment: In vitro co-IP: bait = Flag-PARP-1, prey = WRN xref: IntAct:EBI-372023 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0017312 name: parp1-xrcc5-1 physical interaction comment: In vitro co-IP: bait = FLAG-PARP1, Preys = WRN, Ku70, Ku80 xref: IntAct:EBI-372028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0017313 name: exosc5-sfpq physical interaction xref: IntAct:EBI-373701 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005555 ! EXOS5_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0017314 name: exosc5-znf558 physical interaction xref: IntAct:EBI-373704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005555 ! EXOS5_HUMAN relationship: has_participant CCO:B0058304 ! ZN558_HUMAN [Term] id: CCO:I0017315 name: exosc8-kiaa1604 physical interaction xref: IntAct:EBI-373719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005556 ! EXOS8_HUMAN relationship: has_participant CCO:B0058807 ! NCM_HUMAN [Term] id: CCO:I0017316 name: rrp4-znf408 physical interaction xref: IntAct:EBI-373728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039757 ! EXOS2_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0017317 name: pmscl2-ssrp1 physical interaction xref: IntAct:EBI-373761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005348 ! EXOSX_HUMAN relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN [Term] id: CCO:I0017318 name: pmscl2-ruvbl2 physical interaction xref: IntAct:EBI-373788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005348 ! EXOSX_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN [Term] id: CCO:I0017319 name: lsm1-hspca physical interaction xref: IntAct:EBI-373866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0006005 ! LSM1_HUMAN [Term] id: CCO:I0017320 name: lsm2-znf408-1 physical interaction xref: IntAct:EBI-373884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0062972 ! LSM2_HUMAN [Term] id: CCO:I0017321 name: lsm4-nmi physical interaction xref: IntAct:EBI-373932 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0063157 ! LSM4_HUMAN [Term] id: CCO:I0017322 name: lsm4-pepp2 physical interaction xref: IntAct:EBI-373935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0063157 ! LSM4_HUMAN [Term] id: CCO:I0017323 name: lsm6-pold2 physical interaction xref: IntAct:EBI-373965 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005567 ! LSM6_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN [Term] id: CCO:I0017324 name: lsm7-rab7l1 physical interaction xref: IntAct:EBI-373977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005494 ! LSM7_HUMAN relationship: has_participant CCO:B0054394 ! RAB7L_HUMAN [Term] id: CCO:I0017325 name: lsm7-npy1r physical interaction xref: IntAct:EBI-373980 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005494 ! LSM7_HUMAN relationship: has_participant CCO:B0055187 ! NPY1R_HUMAN [Term] id: CCO:I0017326 name: lsm8-ighmbp2 physical interaction xref: IntAct:EBI-374019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005349 ! LSM8_HUMAN relationship: has_participant CCO:B0055321 ! SMBP2_HUMAN [Term] id: CCO:I0017327 name: lsm8-gtf2i physical interaction xref: IntAct:EBI-374034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005349 ! LSM8_HUMAN relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN [Term] id: CCO:I0017328 name: lsm8-il28ra physical interaction xref: IntAct:EBI-374037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005349 ! LSM8_HUMAN relationship: has_participant CCO:B0057318 ! I28RA_HUMAN [Term] id: CCO:I0017329 name: lsm8-itsn2 physical interaction xref: IntAct:EBI-374040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005349 ! LSM8_HUMAN relationship: has_participant CCO:B0006199 ! ITSN2_HUMAN [Term] id: CCO:I0017330 name: xrn2-itgb4bp physical interaction xref: IntAct:EBI-374112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043429 ! XRN2_HUMAN relationship: has_participant CCO:B0063158 ! IF6_HUMAN [Term] id: CCO:I0017331 name: xrn2-eif3s6ip physical interaction xref: IntAct:EBI-374115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026279 ! IF3EI_HUMAN relationship: has_participant CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:I0017332 name: xrn2-dkfzp686n0351 physical interaction xref: IntAct:EBI-374121 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043429 ! XRN2_HUMAN relationship: has_participant CCO:B0063159 ! PARPT_HUMAN [Term] id: CCO:I0017333 name: xrn2-comt physical interaction xref: IntAct:EBI-374124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043429 ! XRN2_HUMAN relationship: has_participant CCO:B0063160 ! COMT_HUMAN [Term] id: CCO:I0017334 name: xrn2-mocs3 physical interaction xref: IntAct:EBI-374127 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043429 ! XRN2_HUMAN relationship: has_participant CCO:B0063161 ! MOCS3_HUMAN [Term] id: CCO:I0017335 name: xrn2-tollip physical interaction xref: IntAct:EBI-374130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:I0017336 name: xrn2-tardbp physical interaction xref: IntAct:EBI-374133 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043429 ! XRN2_HUMAN relationship: has_participant CCO:B0063162 ! TADBP_HUMAN [Term] id: CCO:I0017337 name: znf408-rgs19ip1 physical interaction xref: IntAct:EBI-374208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054391 ! GIPC1_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0017338 name: znf408-pdlim4 physical interaction xref: IntAct:EBI-374211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017106 ! PDLI4_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0017339 name: znf408-ddx56 physical interaction xref: IntAct:EBI-374214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030377 ! DDX56_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0017340 name: znf408-lsm2 physical interaction xref: IntAct:EBI-374217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0062972 ! LSM2_HUMAN [Term] id: CCO:I0017341 name: znf408-znf408 physical interaction xref: IntAct:EBI-374220 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0017342 name: znf408-noa36 physical interaction xref: IntAct:EBI-374223 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0063163 ! ZN330_HUMAN [Term] id: CCO:I0017343 name: znf408-kiaa1793 physical interaction xref: IntAct:EBI-374226 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0063164 ! CC136_HUMAN [Term] id: CCO:I0017344 name: znf408-mif physical interaction xref: IntAct:EBI-374229 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055021 ! MIF_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0017345 name: znf408-top3b physical interaction xref: IntAct:EBI-374232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054815 ! TOP3B_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN [Term] id: CCO:I0017346 name: c20orf20-epc1-5 physical interaction comment: Interaction detected by comigration through a Suparose 6 gel. xref: IntAct:EBI-399347 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005916 ! EP400_HUMAN relationship: has_participant CCO:B0005917 ! MO4L1_HUMAN [Term] id: CCO:I0017347 name: eif4e-emx2-1 physical interaction comment: Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons xref: IntAct:EBI-399845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055734 ! EMX2_HUMAN [Term] id: CCO:I0017348 name: emx2-eif4e-1 physical interaction comment: Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons xref: IntAct:EBI-399850 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055734 ! EMX2_HUMAN [Term] id: CCO:I0017349 name: eif4e-emx2-2 physical interaction comment: Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons xref: IntAct:EBI-399857 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055734 ! EMX2_HUMAN [Term] id: CCO:I0017350 name: q9nwa0-vdrip-1 physical interaction comment: Interaction detected by GST pulldown. xref: IntAct:EBI-400035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN [Term] id: CCO:I0017351 name: ywhaz-cof1-1 physical interaction comment: GST pull-down: bait= human 14-3-3, prey= human cofilin xref: IntAct:EBI-445573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0017352 name: zcsl2-gnefr-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-465397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026978 ! DPH3_HUMAN relationship: has_participant CCO:B0059123 ! SRGEF_HUMAN [Term] id: CCO:I0017353 name: zcsl2-gnefr-3 physical interaction comment: Interaction detected by co-immunoprecipitation xref: IntAct:EBI-465463 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026978 ! DPH3_HUMAN relationship: has_participant CCO:B0059123 ! SRGEF_HUMAN [Term] id: CCO:I0017354 name: map3k5-ywhaz-1 physical interaction comment: Two hybrid interaction between human map kinase and 14-3-3 zeta xref: IntAct:EBI-476285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0017355 name: map3k5-ywhab-1 physical interaction comment: Two hybrid interaction between human map kinase and 14-3-3 beta xref: IntAct:EBI-476312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0017356 name: map3k5-ywhah-1 physical interaction comment: Two hybrid interaction between human map kinase and 14-3-3 eta xref: IntAct:EBI-476341 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0017357 name: map3k5-ywhae-1 physical interaction comment: Two hybrid interaction between human map kinase and 14-3-3 epsilon xref: IntAct:EBI-476348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0017358 name: fadd-tnfrsf6-1 physical interaction comment: Fas signalling complex by co-immunoprecipitation xref: IntAct:EBI-495129 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0058106 ! CASPA_HUMAN [Term] id: CCO:I0017359 name: dmap1-tsg101 physical interaction comment: The DNA methyltransferase 1-associated protein 1 interacts with the tumor susceptibility gene 101 protein xref: IntAct:EBI-518581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN [Term] id: CCO:I0017360 name: tnfsf10-tnfrs10a-1 physical interaction comment: streptavidin pull-down with biotinylated TRAIL : TRAIL DISC complex xref: IntAct:EBI-518922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0017361 name: tnfsf10-tnfrs10a-3 physical interaction comment: streptavidin pull-down with biotinylated TRAIL : TRAIL DISC complex with TRAIL-R1 xref: IntAct:EBI-518990 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0017362 name: tnfsf10-tnfrs10b-4 physical interaction comment: streptavidin pull-down with biotinylated TRAIL : TRAIL DISC complex with TRAIL-R2 xref: IntAct:EBI-519007 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0017363 name: tac1-blys-3 physical interaction comment: The B-lymphocyte stimulator (BlyS) protein interacts with the tumor necrosis factor receptor superfamily member TAC1 xref: IntAct:EBI-519389 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0017364 name: tac1-april physical interaction comment: The tumor necrosis factor receptor superfamily member TAC1 interacts with the B-lymphocyte stimulator (BlyS) protein homologue: APRIL xref: IntAct:EBI-519414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0054674 ! TNF13_HUMAN [Term] id: CCO:I0017365 name: tac1-ztnf4 physical interaction comment: The tumor necrosis factor receptor family member TAC1 protein interacts with the zTNF4 (BlyS) protein xref: IntAct:EBI-519856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0017366 name: bcma-ztnf4-1 physical interaction comment: The tumor necrosis factor receptor family member BMCA protein interacts with the zTNF4 (BlyS) protein xref: IntAct:EBI-519961 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055707 ! TNR17_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0017367 name: atar-traf5 physical interaction comment: Yeast-2-hybrid reveals interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (ATAR) and the TNF receptor associated factor 5 protein (TRAF5) xref: IntAct:EBI-523893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN [Term] id: CCO:I0017368 name: eif2c2-dicer1-2 physical interaction xref: IntAct:EBI-527834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016049 ! I2C2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0017369 name: rnase3l-dgcr8-1 physical interaction xref: IntAct:EBI-528397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006026 ! RNC_HUMAN relationship: has_participant CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:I0017370 name: eif2c2-dicer1-3 physical interaction xref: IntAct:EBI-528729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016049 ! I2C2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0017371 name: traf6-tiz-3 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the TNF receptor associated factor 6 (TRAF6) protein and the TRAF6-binding zinc finger protein xref: IntAct:EBI-531260 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN [Term] id: CCO:I0017372 name: tcf4-bcl9 physical interaction xref: IntAct:EBI-533249 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:I0017373 name: tak1-stat3-4 physical interaction comment: Identification of TAK1 as a STAT3-Interacting Protein by GST-pulldown xref: IntAct:EBI-593638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:I0017374 name: zn655-vav1-4 physical interaction comment: Interaction between ZN655 (VIK) and VAV1 confirmed by coimmunoprecipitation xref: IntAct:EBI-625655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005578 ! ZN655_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:I0017375 name: zn655-vav1-5 physical interaction comment: Interaction between ZN655 (VIK) and VAV1 confirmed by coimmunoprecipitation xref: IntAct:EBI-625670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005578 ! ZN655_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:I0017376 name: pb1-arid2-5 physical interaction comment: copurification by gel-filtration of a baf200 containing complex which lacks baf180 xref: IntAct:EBI-637945 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0017377 name: rbpsuh-notch1 physical interaction comment: Interaction of CBF-1 with ICNotch1, as detected by coimmunoprecipitation. xref: IntAct:EBI-638058 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN [Term] id: CCO:I0017378 name: rbpsuh-skiip-3 physical interaction comment: Interaction of SKIP with ICNotch1, as detected by coimmunoprecipitation. xref: IntAct:EBI-638096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:I0017379 name: tcp1-atx2-4 physical interaction comment: Colocalisation reveals interaction between T-Plastin and ataxin-2 xref: IntAct:EBI-698780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0019585 ! PLST_HUMAN [Term] id: CCO:I0017380 name: lcp1-atx2-3 physical interaction comment: Colocalisation reveals interaction between L-Plastin and ataxin-2 xref: IntAct:EBI-698784 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:I0017381 name: hsp1-hsp4-3 physical interaction comment: CoIP: bait = myc-HPS4, prey=HA-HPS1 xref: IntAct:EBI-704422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0017382 name: hsp1-hsp4-4 physical interaction comment: CoIP: bait = HA-HPS1, prey=myc-HPS4 xref: IntAct:EBI-704430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0017383 name: mapk14-rps6ka4 physical interaction comment: Interaction between p38alpha and Rsk-B identified by yeast 2-hybrid xref: IntAct:EBI-73975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005629 ! KS6A4_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN [Term] id: CCO:I0017384 name: edf1-pparg-4 physical interaction comment: MBF-1 interacts with PPAR-gamma in a mammalian two-hybrid system. xref: IntAct:EBI-781653 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0017385 name: il7-il7r-2 physical interaction xref: IntAct:EBI-80510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0055060 ! IL7RA_HUMAN [Term] id: CCO:I0017386 name: arnt-erap_140-1 physical interaction comment: Interaction detected by CoIP xref: IntAct:EBI-80822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005552 ! NCOA7_HUMAN [Term] id: CCO:I0017387 name: arnt-ncor2-1 physical interaction comment: Interaction detected by CoIP xref: IntAct:EBI-80847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:I0017388 name: ikbkb-ikbkg-2 physical interaction xref: IntAct:EBI-81316 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017389 name: mycn-max-1 physical interaction comment: Interaction between human MycN and MAX detected by Y2H xref: IntAct:EBI-878383 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005336 ! MAX_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:I0017390 name: mycn-nmi-1 physical interaction comment: Interaction between human MycN and Nmi detected by Y2H xref: IntAct:EBI-878416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:I0017391 name: hdac1-dnmt3l direct interaction xref: IntAct:EBI-904606 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0037714 ! DNM3L_HUMAN [Term] id: CCO:I0017392 name: hdac1-dnmt3l-1 direct interaction xref: IntAct:EBI-904617 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0037714 ! DNM3L_HUMAN [Term] id: CCO:I0017393 name: grem1-14_3_3 eta-1 direct interaction comment: Pulldown analysis reveals interaction between the Gremlin 1 protein and YWHAH protein xref: IntAct:EBI-914576 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0063191 ! GREM1_HUMAN [Term] id: CCO:I0017394 name: 14_3_3 eta-grem1 direct interaction comment: Pulldown analysis reveals interaction between the YWHAH protein and Gremlin 1 protein xref: IntAct:EBI-914594 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0063191 ! GREM1_HUMAN [Term] id: CCO:I0017395 name: nck-sos1-1 physical interaction comment: Pull-down in a leukemia cell line: bait = nck SH3 domain 3, prey= sos1 xref: IntAct:EBI-922883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN [Term] id: CCO:I0017396 name: nck-dnm1-2 physical interaction comment: Pull-down in a leukemia cell line: bait = nck SH3 domain 3, prey= dynamin xref: IntAct:EBI-922956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022139 ! DYN1_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN [Term] id: CCO:I0017397 name: grb2-dnm1-4 physical interaction comment: Pull-down in a leukemia cell line: bait = GRB2, prey= dynamin xref: IntAct:EBI-923033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:I0017398 name: mycn-nmi-6 physical interaction comment: Interaction between human MycN and Nmi detected by Y2H xref: IntAct:EBI-928412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:I0017399 name: hbxap-smarca5-4 physical interaction xref: IntAct:EBI-928837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:I0017400 name: mx1-trpc6-4 physical interaction comment: Co-IP: bait = TRPC6 ARD domain, prey = MxA xref: IntAct:EBI-929638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0062980 ! TRPC6_HUMAN [Term] id: CCO:I0017401 name: mx1-trpc1-1 physical interaction comment: Co-IP: bait = TRPC1 ARD domain, prey = MxA xref: IntAct:EBI-929688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025169 ! TRPC1_HUMAN relationship: has_participant CCO:B0055123 ! MX1_HUMAN [Term] id: CCO:I0017402 name: mx1-trpc3-2 physical interaction comment: Co-IP: bait = TRPC3 ARD domain, prey = MxA xref: IntAct:EBI-929707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0063192 ! TRPC3_HUMAN [Term] id: CCO:I0017403 name: mx1-trpc4-2 physical interaction comment: Co-IP: bait = TRPC4 ARD domain, prey = MxA xref: IntAct:EBI-929717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025166 ! TRPC4_HUMAN relationship: has_participant CCO:B0055123 ! MX1_HUMAN [Term] id: CCO:I0017404 name: fam48a-mapk14 physical interaction xref: IntAct:EBI-970425 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0063193 ! FA48A_HUMAN [Term] id: CCO:I0017405 name: dicer1-tarbp2-2 direct interaction xref: IntAct:EBI-979118 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0017406 name: tarbp2-dicer direct interaction xref: IntAct:EBI-980497 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0017407 name: atg7-map1lc3b direct interaction comment: Interaction between Atg7 and LC3 proteins xref: IntAct:EBI-987896 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006342 ! MLP3B_HUMAN relationship: has_participant CCO:B0054750 ! ATG7_HUMAN [Term] id: CCO:I0017408 name: atg7-gabarap direct interaction comment: Interaction between Atg7 and GABARAP proteins xref: IntAct:EBI-988006 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006196 ! GBRAP_HUMAN relationship: has_participant CCO:B0054750 ! ATG7_HUMAN [Term] id: CCO:I0017409 name: atg7-gabarapl2 direct interaction comment: Interaction between Atg7 and GABARAPL2 proteins xref: IntAct:EBI-988052 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0051349 ! GBRL2_HUMAN relationship: has_participant CCO:B0054750 ! ATG7_HUMAN [Term] id: CCO:I0017410 name: tfrc-tf physical interaction xref: IntAct:EBI-988946 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054876 ! TRFE_HUMAN relationship: has_participant CCO:B0063056 ! TFR1_HUMAN [Term] id: CCO:I0017411 name: setdb1-dnmt3a-1 physical interaction xref: IntAct:EBI-995105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:I0017412 name: setdb1-dnmt3a-3 physical interaction xref: IntAct:EBI-995326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:I0017413 name: morf4l2-mrfap1-1 physical interaction xref: IntAct:EBI-995721 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0063194 ! MOFA1_HUMAN [Term] id: CCO:I0017414 name: gstp1-traf2-2 physical interaction comment: Coimmunoprecipitation assay reveals interaction between GSTP1 and TRAF2 proteins xref: IntAct:EBI-996285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN [Term] id: CCO:I0017415 name: gstp1-traf2-4 physical interaction comment: Coimmunoprecipitation assay reveals interaction between GSTP1 and TRAF2 proteins xref: IntAct:EBI-996387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN [Term] id: CCO:I0017416 name: traf2-ask1 physical interaction comment: Coimmunoprecipitation assay reveals interaction between TRAF2 and ASK1 proteins xref: IntAct:EBI-996434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0017417 name: traf2-mekk1 physical interaction comment: Coimmunoprecipitation assay reveals interaction between TRAF2 and MEKK1 proteins xref: IntAct:EBI-996480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0017418 name: tank-traf3-1 direct interaction comment: Downstream regulator tank binds to the cd40 recognition site on traf3 xref: IntAct:EBI-1033458 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0017419 name: tank-traf3-2 direct interaction comment: Downstream regulator tank binds to the cd40 recognition site on traf3 xref: IntAct:EBI-1033469 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN [Term] id: CCO:I0017420 name: fnta-fntb-14 direct interaction comment: Human protein farnesyltransferase complexed with fpp and r115777 xref: IntAct:EBI-1039209 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:I0017421 name: disc1-akap9 physical interaction xref: IntAct:EBI-1105420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005588 ! AKAP9_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0017422 name: tnik-akap9 physical interaction xref: IntAct:EBI-1105426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005588 ! AKAP9_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:I0017423 name: tnik-ank2 physical interaction xref: IntAct:EBI-1105431 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0041516 ! ANK2_HUMAN [Term] id: CCO:I0017424 name: dtnbp1-brf1 physical interaction xref: IntAct:EBI-1105453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN relationship: has_participant CCO:B0050546 ! TF3B_HUMAN [Term] id: CCO:I0017425 name: cep63-camkk2 physical interaction xref: IntAct:EBI-1105499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005590 ! CEP63_HUMAN relationship: has_participant CCO:B0058383 ! KKCC2_HUMAN [Term] id: CCO:I0017426 name: tnik-cnksr2 physical interaction xref: IntAct:EBI-1105590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0058022 ! CNKR2_HUMAN [Term] id: CCO:I0017427 name: disc1-dpysl2 physical interaction xref: IntAct:EBI-1105683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0056150 ! DPYL2_HUMAN [Term] id: CCO:I0017428 name: disc1-dpysl3 physical interaction xref: IntAct:EBI-1105688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0055970 ! DPYL3_HUMAN [Term] id: CCO:I0017429 name: disc1-eif3s3-6 physical interaction xref: IntAct:EBI-1105764 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0017430 name: disc1-eif3s3-7 physical interaction xref: IntAct:EBI-1105770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0017431 name: disc1-gnb1 physical interaction xref: IntAct:EBI-1105816 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0055621 ! GBB1_HUMAN [Term] id: CCO:I0017432 name: tnik-hars physical interaction xref: IntAct:EBI-1105832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0063195 ! SYHC_HUMAN [Term] id: CCO:I0017433 name: disc1-hapip physical interaction xref: IntAct:EBI-1105862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:I0017434 name: mitap1-hapip physical interaction xref: IntAct:EBI-1105867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0054534 ! KALRN_HUMAN [Term] id: CCO:I0017435 name: disc1-kiaa0826 physical interaction xref: IntAct:EBI-1105898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054711 ! FRYL_HUMAN [Term] id: CCO:I0017436 name: disc1-kiaa0826-1 physical interaction xref: IntAct:EBI-1105903 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054711 ! FRYL_HUMAN [Term] id: CCO:I0017437 name: tnik-kibra physical interaction xref: IntAct:EBI-1105950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0006200 ! WWC1_HUMAN [Term] id: CCO:I0017438 name: disc1-kifap3 physical interaction xref: IntAct:EBI-1105996 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0058104 ! KIFA3_HUMAN [Term] id: CCO:I0017439 name: disc1-myt1l physical interaction xref: IntAct:EBI-1106112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0005601 ! MYT1L_HUMAN [Term] id: CCO:I0017440 name: tnik-myt1l physical interaction xref: IntAct:EBI-1106118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005601 ! MYT1L_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:I0017441 name: tnik-ncor2 physical interaction xref: IntAct:EBI-1106128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:I0017442 name: tnik-nef3 physical interaction xref: IntAct:EBI-1106149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:I0017443 name: disc1-ppp4r1 physical interaction xref: IntAct:EBI-1106242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0057959 ! PP4R1_HUMAN [Term] id: CCO:I0017444 name: dtnbp1-rab11a physical interaction xref: IntAct:EBI-1106257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN relationship: has_participant CCO:B0038438 ! RB11A_HUMAN [Term] id: CCO:I0017445 name: disc1-sh3bp5 physical interaction xref: IntAct:EBI-1106298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN [Term] id: CCO:I0017446 name: disc1-sh3bp5-1 physical interaction xref: IntAct:EBI-1106303 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN [Term] id: CCO:I0017447 name: exoc1-sh3bp5 physical interaction xref: IntAct:EBI-1106308 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005592 ! EXOC1_HUMAN relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN [Term] id: CCO:I0017448 name: disc1-smarce1-1 physical interaction xref: IntAct:EBI-1106318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0017449 name: cep63-snrp70 physical interaction xref: IntAct:EBI-1106338 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005590 ! CEP63_HUMAN relationship: has_participant CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:I0017450 name: disc1-snx6-1 physical interaction xref: IntAct:EBI-1106349 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0026583 ! SNX6_HUMAN [Term] id: CCO:I0017451 name: mitap1-snx6 physical interaction xref: IntAct:EBI-1106354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0026583 ! SNX6_HUMAN [Term] id: CCO:I0017452 name: sh3bp5-sos1 physical interaction xref: IntAct:EBI-1106364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN [Term] id: CCO:I0017453 name: disc1-sptan1 physical interaction xref: IntAct:EBI-1106374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0017454 name: disc1-sptan1-1 physical interaction xref: IntAct:EBI-1106379 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0017455 name: cep63-sptan1 physical interaction xref: IntAct:EBI-1106384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005590 ! CEP63_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0017456 name: exoc1-sptan1 physical interaction xref: IntAct:EBI-1106390 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005592 ! EXOC1_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0017457 name: disc1-sptbn1 physical interaction xref: IntAct:EBI-1106400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0017458 name: disc1-sptbn1-1 physical interaction xref: IntAct:EBI-1106405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0017459 name: disc1-sptbn1-2 physical interaction xref: IntAct:EBI-1106410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0017460 name: cep63-sptbn1 physical interaction xref: IntAct:EBI-1106415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005590 ! CEP63_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0017461 name: tnik-sptbn1 physical interaction xref: IntAct:EBI-1106420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN [Term] id: CCO:I0017462 name: disc1-srgap2 physical interaction xref: IntAct:EBI-1106430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054598 ! FNBP2_HUMAN [Term] id: CCO:I0017463 name: tnik-srgap3 physical interaction xref: IntAct:EBI-1106435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0054466 ! SRGP2_HUMAN [Term] id: CCO:I0017464 name: disc1-tnik physical interaction xref: IntAct:EBI-1106465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:I0017465 name: disc1-tnik-1 physical interaction xref: IntAct:EBI-1106470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN [Term] id: CCO:I0017466 name: disc1-tnks physical interaction xref: IntAct:EBI-1106475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:I0017467 name: sh3bp5-tnks physical interaction xref: IntAct:EBI-1106480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN relationship: has_participant CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:I0017468 name: tnik-trim2 physical interaction xref: IntAct:EBI-1106500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0063196 ! TRIM2_HUMAN [Term] id: CCO:I0017469 name: disc1-trio physical interaction xref: IntAct:EBI-1106510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054681 ! TRIO_HUMAN [Term] id: CCO:I0017470 name: disc1-trio-1 physical interaction xref: IntAct:EBI-1106515 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054681 ! TRIO_HUMAN [Term] id: CCO:I0017471 name: disc1-trio-2 physical interaction xref: IntAct:EBI-1106520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054681 ! TRIO_HUMAN [Term] id: CCO:I0017472 name: exoc1-trio physical interaction xref: IntAct:EBI-1106525 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005592 ! EXOC1_HUMAN relationship: has_participant CCO:B0054681 ! TRIO_HUMAN [Term] id: CCO:I0017473 name: disc1-tubb2 physical interaction xref: IntAct:EBI-1106530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN [Term] id: CCO:I0017474 name: disc1-xrn2 physical interaction xref: IntAct:EBI-1106556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0043429 ! XRN2_HUMAN [Term] id: CCO:I0017475 name: disc1-ywhae physical interaction xref: IntAct:EBI-1106561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0017476 name: disc1-ywhae-1 physical interaction xref: IntAct:EBI-1106566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0017477 name: disc1-ywhaz-1 physical interaction xref: IntAct:EBI-1106586 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0017478 name: mitap1-znf10 physical interaction xref: IntAct:EBI-1106596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0055132 ! ZNF10_HUMAN [Term] id: CCO:I0017479 name: mitap1-znf17 physical interaction xref: IntAct:EBI-1106601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0055067 ! ZNF17_HUMAN [Term] id: CCO:I0017480 name: disc1-znf197 physical interaction xref: IntAct:EBI-1106606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054369 ! ZN197_HUMAN [Term] id: CCO:I0017481 name: mitap1-znf197 physical interaction xref: IntAct:EBI-1106611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0054369 ! ZN197_HUMAN [Term] id: CCO:I0017482 name: mitap1-znf211 physical interaction xref: IntAct:EBI-1106616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0039108 ! ZN211_HUMAN [Term] id: CCO:I0017483 name: mitap1-znf230 physical interaction xref: IntAct:EBI-1106621 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0059158 ! ZN230_HUMAN [Term] id: CCO:I0017484 name: dtnbp1-znf490 physical interaction xref: IntAct:EBI-1106631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005258 ! DTBP1_HUMAN relationship: has_participant CCO:B0059229 ! ZN490_HUMAN [Term] id: CCO:I0017485 name: mitap1-znf91 physical interaction xref: IntAct:EBI-1106636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005926 ! NDEL1_HUMAN relationship: has_participant CCO:B0055742 ! ZNF91_HUMAN [Term] id: CCO:I0017486 name: cftr-edg4 physical interaction xref: IntAct:EBI-1149539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN [Term] id: CCO:I0017487 name: act16b-smarca2-1 physical interaction xref: IntAct:EBI-1168644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0016782 ! ACL6B_HUMAN [Term] id: CCO:I0017488 name: cftr-asha1 physical interaction xref: IntAct:EBI-1171098 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005448 ! CLCA_HUMAN relationship: has_participant CCO:B0005559 ! SNX9_HUMAN relationship: has_participant CCO:B0005581 ! CADH1_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0005875 ! CD59_HUMAN relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0020561 ! PLD2_HUMAN relationship: has_participant CCO:B0030251 ! GNA11_HUMAN relationship: has_participant CCO:B0031883 ! Q9UMI9_HUMAN relationship: has_participant CCO:B0032137 ! PKHA6_HUMAN relationship: has_participant CCO:B0032521 ! LRRF2_HUMAN relationship: has_participant CCO:B0054762 ! SVIL_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0055668 ! DAB2_HUMAN relationship: has_participant CCO:B0058711 ! MS4A5_HUMAN relationship: has_participant CCO:B0059005 ! IRPL1_HUMAN relationship: has_participant CCO:B0062977 ! FLOT2_HUMAN relationship: has_participant CCO:B0062984 ! LEG4_HUMAN relationship: has_participant CCO:B0063054 ! TPM3_HUMAN relationship: has_participant CCO:B0063097 ! TMOD3_HUMAN relationship: has_participant CCO:B0063197 ! MUC13_HUMAN relationship: has_participant CCO:B0063198 ! SORL_HUMAN relationship: has_participant CCO:B0063199 ! REPS1_HUMAN relationship: has_participant CCO:B0063200 ! SH3L2_HUMAN relationship: has_participant CCO:B0063201 ! EPN4_HUMAN relationship: has_participant CCO:B0063202 ! ATD3A_HUMAN relationship: has_participant CCO:B0063203 ! AT2A3_HUMAN relationship: has_participant CCO:B0063204 ! AP1B1_HUMAN relationship: has_participant CCO:B0063205 ! TACD1_HUMAN [Term] id: CCO:I0017489 name: spta1-sptb2-1 direct interaction comment: Interaction between SPTA1 and SPTB2 identified by GST pulldown xref: IntAct:EBI-1177624 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0063212 ! SPTA1_HUMAN [Term] id: CCO:I0017490 name: brm-mecp2-2 physical interaction xref: IntAct:EBI-1189084 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:I0017491 name: brm-mecp2-3 physical interaction xref: IntAct:EBI-1189093 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0055470 ! MECP2_HUMAN [Term] id: CCO:I0017492 name: abcb1-rnf2-1 physical interaction comment: P-glycoprotein coimmunoprecipitates RNF2 from Sf9 cell lysates xref: IntAct:EBI-1199741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020552 ! RING2_HUMAN relationship: has_participant CCO:B0062993 ! MDR1_HUMAN [Term] id: CCO:I0017493 name: app-hadh2-1 physical interaction comment: amyloid beta-HADH2(ERAB) interaction demonstrated by ligand binding. xref: IntAct:EBI-371703 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063213 ! HCD2_HUMAN [Term] id: CCO:I0017494 name: ixl-crsp6-4 physical interaction comment: Interaction detected by Anti FLAG affinity chromatography. xref: IntAct:EBI-399565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN [Term] id: CCO:I0017495 name: ywhaz-cof1-2 physical interaction comment: affinity chromatography: bait= human 14-3-3, prey= human cofilin xref: IntAct:EBI-445553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0017496 name: hd-git1-5 physical interaction comment: CoIP from human brain : bait = endogenous huntingtin, bait= endogenous GIT-1 xref: IntAct:EBI-472960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0017497 name: ywhaz-map3k5-1 physical interaction comment: in vitro pulldown interaction between 14-3-3 zeta and map kinase map3k5 xref: IntAct:EBI-476374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0017498 name: tnfsf10-tnfrs10a-2 physical interaction comment: streptavidin pull-down with biotinylated TRAIL : TRAIL DISC complex xref: IntAct:EBI-518950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0017499 name: ang-actn2-1 physical interaction comment: Y2H: bait= human angiogenin, prey= human alpha-actinin-2 xref: IntAct:EBI-525300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN [Term] id: CCO:I0017500 name: irak-traf6-1 physical interaction comment: Coimmunoprecipitation reveals interaction between Interleukin-1 receptor-associated kinase 1 (IRAK1) and the TNF receptor associated factor 6 (TRAF6) protein xref: IntAct:EBI-525876 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:I0017501 name: traf6-tab1 physical interaction comment: Coimmunoprecipitation reveals interaction between the TNF receptor associated factor 6 (TRAF6) protein and TAB1, TAB2 and TAK1 proteins xref: IntAct:EBI-525891 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0017502 name: tac1-tall_1 physical interaction comment: FACS analysis reveals interaction between the Tumor necrosis factor receptor superfamily member 13B (TAC1) and the Tumor necrosis factor ligand superfamily member 13B (TALL-1) xref: IntAct:EBI-529611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0017503 name: tac1-tall_1-1 physical interaction comment: FACS analysis reveals interaction between the Tumor necrosis factor receptor superfamily member 13B (TAC1) and the Tumor necrosis factor ligand superfamily member 13B (TALL-1) xref: IntAct:EBI-529619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0017504 name: tnfr2-traf1 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the Tumor necrosis factor receptor superfamily member 1B precursor (TNFR2) and TNF receptor associated factor 1 (TRAF1) xref: IntAct:EBI-529958 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017505 name: traf1-traf2-1 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the TNF receptor associated factor 1 (TRAF1) and TNF receptor associated factor 2 (TRAF2) xref: IntAct:EBI-530026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017506 name: traf2-traf1 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the TNF receptor associated factor 2 (TRAF2) and TNF receptor associated factor 1 (TRAF1) xref: IntAct:EBI-530107 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017507 name: traf2-traf2-2 physical interaction comment: Directed yeast-2-hybrid reveals self association of the TNF receptor associated factor 2 (TRAF2) protein xref: IntAct:EBI-530122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN [Term] id: CCO:I0017508 name: traf1-traf1-1 physical interaction comment: Directed yeast-2-hybrid reveals self association of the TNF receptor associated factor 1 (TRAF1) protein xref: IntAct:EBI-530131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0017509 name: tnfr2-traf2-2 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the Tumor necrosis factor receptor superfamily member 1B precursor (TNFR2) and TNF receptor associated factor 2 (TRAF2) xref: IntAct:EBI-530297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0017510 name: mll-mll-2 physical interaction comment: Interaction of human MLL, as detected by affinity coimmunoprecipitation. xref: IntAct:EBI-591588 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:I0017511 name: rac1-arfaptin2 direct interaction comment: Interaction of POR1 and Rac1 detected by GST pull down. xref: IntAct:EBI-687900 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0017512 name: itga2b-itga2b-2 direct interaction comment: SDS-PAGE: oligomerization of alpha II b integrin xref: IntAct:EBI-702780 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:I0017513 name: itga2b-itga2b-5 direct interaction comment: Ultracentrifugation: oligomerization of alpha II b integrin xref: IntAct:EBI-702903 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:I0017514 name: itgb3-itgb3-2 direct interaction comment: Ultracentrifugation: Oligomerization of integrin beta3 xref: IntAct:EBI-702911 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0017515 name: hsp1-hsp4-9 physical interaction comment: Size-exculsion : co-elution of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0017516 name: edf1-pparg-1 physical interaction comment: MBF-1 interacts in vitro with PPAR-gamma as detected by pull-down experiments. xref: IntAct:EBI-781420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0017517 name: edf1-nr1h3-4 physical interaction comment: MBF-1 interacts with LXR alpha in a mammalian two-hybrid system. xref: IntAct:EBI-781627 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054582 ! EDF1_HUMAN relationship: has_participant CCO:B0055878 ! NR1H3_HUMAN [Term] id: CCO:I0017518 name: il7-il7r-1 physical interaction xref: IntAct:EBI-80504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0055060 ! IL7RA_HUMAN [Term] id: CCO:I0017519 name: il7-il2rg-2 physical interaction xref: IntAct:EBI-80507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0055246 ! IL2RG_HUMAN [Term] id: CCO:I0017520 name: ezh2-dnmt1 physical interaction xref: IntAct:EBI-923644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0017521 name: ezh2-dnmt3a physical interaction xref: IntAct:EBI-923669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0017522 name: ezh2-dnmt3b physical interaction xref: IntAct:EBI-923677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0017523 name: areg-ubqln4 physical interaction xref: IntAct:EBI-954718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055039 ! AREG_HUMAN [Term] id: CCO:I0017524 name: c19orf10-ubqln4 physical interaction xref: IntAct:EBI-954750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0058132 ! CS010_HUMAN [Term] id: CCO:I0017525 name: runx1t1-ubqln4 physical interaction xref: IntAct:EBI-954766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055769 ! MTG8_HUMAN [Term] id: CCO:I0017526 name: ccl21-ubqln4 physical interaction xref: IntAct:EBI-954774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0054334 ! CCL21_HUMAN [Term] id: CCO:I0017527 name: dtx2-ubqln4 physical interaction xref: IntAct:EBI-954830 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0017528 name: elf5-ubqln4 physical interaction xref: IntAct:EBI-954846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0059208 ! ELF5_HUMAN [Term] id: CCO:I0017529 name: fgfbp1-ubqln4 physical interaction xref: IntAct:EBI-954854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0005646 ! FGFP1_HUMAN [Term] id: CCO:I0017530 name: fzd7-ubqln4 physical interaction xref: IntAct:EBI-954910 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0038856 ! FZD7_HUMAN [Term] id: CCO:I0017531 name: gabrd-ubqln4 physical interaction xref: IntAct:EBI-954918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0022931 ! GBRD_HUMAN [Term] id: CCO:I0017532 name: igfbp6-ubqln4 physical interaction xref: IntAct:EBI-954958 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055173 ! IBP6_HUMAN [Term] id: CCO:I0017533 name: ighm-ubqln4 physical interaction xref: IntAct:EBI-954966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0049019 ! IGHM_HUMAN [Term] id: CCO:I0017534 name: mllt6-ubqln4-1 physical interaction xref: IntAct:EBI-955006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0042847 ! AF17_HUMAN [Term] id: CCO:I0017535 name: nme3-ubqln4 physical interaction xref: IntAct:EBI-955014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005316 ! NDK3_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0017536 name: nphp1-ubqln4 physical interaction xref: IntAct:EBI-955022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0054420 ! NPHP1_HUMAN [Term] id: CCO:I0017537 name: ppic-ubqln4 physical interaction xref: IntAct:EBI-955102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0033592 ! PPIC_HUMAN [Term] id: CCO:I0017538 name: scmh1-ubqln4 physical interaction xref: IntAct:EBI-955158 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:I0017539 name: sgne1-ubqln4-1 physical interaction xref: IntAct:EBI-955190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0037954 ! 7B2_HUMAN [Term] id: CCO:I0017540 name: tmepai-ubqln4 physical interaction xref: IntAct:EBI-955238 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0058144 ! PMEPA_HUMAN [Term] id: CCO:I0017541 name: vip-ubqln4 physical interaction xref: IntAct:EBI-955262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0054849 ! VIP_HUMAN [Term] id: CCO:I0017542 name: znf205-ubqln4 physical interaction xref: IntAct:EBI-955278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0054735 ! ZN205_HUMAN [Term] id: CCO:I0017543 name: dvl2-a2bp1 physical interaction xref: IntAct:EBI-955286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0017544 name: hnrpf-a2bp1 physical interaction xref: IntAct:EBI-955294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005814 ! HNRPF_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0017545 name: kifap3-a2bp1 physical interaction xref: IntAct:EBI-955302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058104 ! KIFA3_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0017546 name: numbl-a2bp1 physical interaction xref: IntAct:EBI-955318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059414 ! NUMBL_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0017547 name: tsc22d4-pdcd8 physical interaction xref: IntAct:EBI-955326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0017548 name: baiap2-atn1 physical interaction xref: IntAct:EBI-955334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:I0017549 name: runx1t1-atn1 physical interaction xref: IntAct:EBI-955342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0055769 ! MTG8_HUMAN [Term] id: CCO:I0017550 name: ewsr1-atn1 physical interaction xref: IntAct:EBI-955350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0017551 name: mdfi-atn1 physical interaction xref: IntAct:EBI-955374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0017552 name: nck2-atn1 physical interaction xref: IntAct:EBI-955390 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:I0017553 name: atp6v0d1-atxn1 physical interaction xref: IntAct:EBI-955414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063214 ! VA0D1_HUMAN [Term] id: CCO:I0017554 name: cpsf5-atxn1 physical interaction xref: IntAct:EBI-955446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062837 ! CPSF5_HUMAN [Term] id: CCO:I0017555 name: crk-atxn1 physical interaction xref: IntAct:EBI-955454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:I0017556 name: cxorf20-atxn1 physical interaction xref: IntAct:EBI-955462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0031918 ! CX020_HUMAN [Term] id: CCO:I0017557 name: efemp2-atxn1 physical interaction xref: IntAct:EBI-955470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0017558 name: fam46a-atxn1 physical interaction xref: IntAct:EBI-955478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063215 ! FA46A_HUMAN [Term] id: CCO:I0017559 name: fam46b-atxn1 physical interaction xref: IntAct:EBI-955486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062965 ! FA46B_HUMAN [Term] id: CCO:I0017560 name: zc3h10-atxn1 physical interaction xref: IntAct:EBI-955494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063216 ! ZC3HA_HUMAN [Term] id: CCO:I0017561 name: q9h7h0-atxn1 physical interaction xref: IntAct:EBI-955502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063217 ! M11D1_HUMAN [Term] id: CCO:I0017562 name: kiaa0174-atxn1 physical interaction xref: IntAct:EBI-955510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0026635 ! K0174_HUMAN [Term] id: CCO:I0017563 name: numbl-atxn1 physical interaction xref: IntAct:EBI-955526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059414 ! NUMBL_HUMAN [Term] id: CCO:I0017564 name: pcqap-atxn1 physical interaction xref: IntAct:EBI-955534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN [Term] id: CCO:I0017565 name: sfrs16-atxn1 physical interaction xref: IntAct:EBI-955558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062947 ! SFR16_HUMAN [Term] id: CCO:I0017566 name: tcap-atxn1 physical interaction xref: IntAct:EBI-955566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005387 ! TELT_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0017567 name: fazf-atxn1 physical interaction xref: IntAct:EBI-955574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059324 ! ZBT32_HUMAN [Term] id: CCO:I0017568 name: u2af2-atxn1 physical interaction xref: IntAct:EBI-955582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:I0017569 name: zcchc13-atxn1 physical interaction xref: IntAct:EBI-955590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063218 ! ZCH13_HUMAN [Term] id: CCO:I0017570 name: znrd1-atxn2 physical interaction xref: IntAct:EBI-955598 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005622 ! RPA12_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0017571 name: ewsr1-atxn3 physical interaction xref: IntAct:EBI-955606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0049689 ! ATX3_HUMAN [Term] id: CCO:I0017572 name: trim22-cic physical interaction xref: IntAct:EBI-955622 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057390 ! TRI22_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0017573 name: znrd1-cic physical interaction xref: IntAct:EBI-955630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005622 ! RPA12_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0017574 name: dnaja3-coil physical interaction xref: IntAct:EBI-955686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0017575 name: nif3l1-coil physical interaction xref: IntAct:EBI-955766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:I0017576 name: taf9-coil physical interaction xref: IntAct:EBI-955790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:I0017577 name: tceb3b-coil physical interaction xref: IntAct:EBI-955798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN [Term] id: CCO:I0017578 name: zbtb25-coil physical interaction xref: IntAct:EBI-955806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0055169 ! ZBT25_HUMAN [Term] id: CCO:I0017579 name: ewsr1-ercc5 physical interaction xref: IntAct:EBI-955814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0006036 ! ERCC5_HUMAN [Term] id: CCO:I0017580 name: ewsr1-pcbp1 physical interaction xref: IntAct:EBI-955870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:I0017581 name: tsc22d4-prnp physical interaction xref: IntAct:EBI-955894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0043436 ! PRIO_HUMAN [Term] id: CCO:I0017582 name: trim22-rere physical interaction xref: IntAct:EBI-956014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043437 ! RERE_HUMAN relationship: has_participant CCO:B0057390 ! TRI22_HUMAN [Term] id: CCO:I0017583 name: lmo3-rora physical interaction xref: IntAct:EBI-956022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN [Term] id: CCO:I0017584 name: nr0b1-rora-1 physical interaction xref: IntAct:EBI-956030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0055483 ! NR0B1_HUMAN [Term] id: CCO:I0017585 name: tsc22d4-sacs physical interaction xref: IntAct:EBI-956046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005994 ! SACS_HUMAN [Term] id: CCO:I0017586 name: znrd1-sacs physical interaction xref: IntAct:EBI-956054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005622 ! RPA12_HUMAN relationship: has_participant CCO:B0005994 ! SACS_HUMAN [Term] id: CCO:I0017587 name: rnf138-taf9 physical interaction xref: IntAct:EBI-956062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0063219 ! RN138_HUMAN [Term] id: CCO:I0017588 name: rps14-taf9-1 physical interaction xref: IntAct:EBI-956070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN [Term] id: CCO:I0017589 name: taf6l-taf9 physical interaction xref: IntAct:EBI-956078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0023501 ! TAF6L_HUMAN [Term] id: CCO:I0017590 name: ube1-taf9 physical interaction xref: IntAct:EBI-956086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0063177 ! UBA1_HUMAN [Term] id: CCO:I0017591 name: fate1-tbp physical interaction xref: IntAct:EBI-956094 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0062910 ! FATE1_HUMAN [Term] id: CCO:I0017592 name: rara-ube3a physical interaction xref: IntAct:EBI-956134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005334 ! UBE3A_HUMAN relationship: has_participant CCO:B0024853 ! RARA_HUMAN [Term] id: CCO:I0017593 name: trim22-usp7 physical interaction xref: IntAct:EBI-956206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005429 ! UBP7_HUMAN relationship: has_participant CCO:B0057390 ! TRI22_HUMAN [Term] id: CCO:I0017594 name: ubqln4-dkk3 physical interaction xref: IntAct:EBI-956246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0059080 ! DKK3_HUMAN [Term] id: CCO:I0017595 name: ubqln4-dtx2-1 physical interaction xref: IntAct:EBI-956254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0017596 name: ubqln4-pip5k2b-1 physical interaction xref: IntAct:EBI-956286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055640 ! PI42B_HUMAN [Term] id: CCO:I0017597 name: ubqln4-lat2 physical interaction xref: IntAct:EBI-956342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0058644 ! NTAL_HUMAN [Term] id: CCO:I0017598 name: aptx-trim37-1 physical interaction xref: IntAct:EBI-956382 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0005943 ! APTX_HUMAN [Term] id: CCO:I0017599 name: aptx-xrcc4 physical interaction xref: IntAct:EBI-956390 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005651 ! XRCC4_HUMAN relationship: has_participant CCO:B0005943 ! APTX_HUMAN [Term] id: CCO:I0017600 name: atn1-mdfi physical interaction xref: IntAct:EBI-956406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0017601 name: atn1-trip6-1 physical interaction xref: IntAct:EBI-956446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:I0017602 name: atxn1-dazap2-1 physical interaction xref: IntAct:EBI-956454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0017603 name: atxn1-klhl12-1 physical interaction xref: IntAct:EBI-956462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0056358 ! KLH12_HUMAN [Term] id: CCO:I0017604 name: atxn1-otx2 physical interaction xref: IntAct:EBI-956470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055255 ! OTX2_HUMAN [Term] id: CCO:I0017605 name: atxn1-plekha5-1 physical interaction xref: IntAct:EBI-956478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063010 ! PKHA5_HUMAN [Term] id: CCO:I0017606 name: atxn1-rbm9-5 physical interaction xref: IntAct:EBI-956486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0017607 name: atxn1-rbpms-1 physical interaction xref: IntAct:EBI-956494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005178 ! RBPMS_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0017608 name: atxn1-tbc1d5-1 physical interaction xref: IntAct:EBI-956502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0058070 ! TBCD5_HUMAN [Term] id: CCO:I0017609 name: atxn1-traf2-1 physical interaction xref: IntAct:EBI-956510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0017610 name: atxn1-trim32-1 physical interaction xref: IntAct:EBI-956518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062794 ! TRI32_HUMAN [Term] id: CCO:I0017611 name: atxn1-u2af2-2 physical interaction xref: IntAct:EBI-956526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:I0017612 name: atxn2-idh3b physical interaction xref: IntAct:EBI-956534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0063220 ! IDH3B_HUMAN [Term] id: CCO:I0017613 name: atxn2-ncoa4 physical interaction xref: IntAct:EBI-956542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0041593 ! NCOA4_HUMAN [Term] id: CCO:I0017614 name: atxn3-rad23a physical interaction xref: IntAct:EBI-956566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0049689 ! ATX3_HUMAN relationship: has_participant CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:I0017615 name: atxn3-rad23b physical interaction xref: IntAct:EBI-956574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020493 ! RD23B_HUMAN relationship: has_participant CCO:B0049689 ! ATX3_HUMAN [Term] id: CCO:I0017616 name: atxn7l2-mdfi physical interaction xref: IntAct:EBI-956590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0063221 ! AT7L2_HUMAN [Term] id: CCO:I0017617 name: atxn7l3-usp6 physical interaction xref: IntAct:EBI-956606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005946 ! Q8IY68_HUMAN relationship: has_participant CCO:B0055277 ! UBP6_HUMAN [Term] id: CCO:I0017618 name: cic-gabpb2 physical interaction xref: IntAct:EBI-956614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040683 ! GABP1_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0017619 name: pqbp1-rcv1 physical interaction xref: IntAct:EBI-956734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN relationship: has_participant CCO:B0055281 ! RECO_HUMAN [Term] id: CCO:I0017620 name: pqbp1-wbp11 physical interaction xref: IntAct:EBI-956742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005313 ! WBP11_HUMAN relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN [Term] id: CCO:I0017621 name: rere-krtap4_12 physical interaction xref: IntAct:EBI-956758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005293 ! KR412_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0017622 name: rere-plscr1 physical interaction xref: IntAct:EBI-956766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038636 ! PLS1_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0017623 name: taf9-drap1 physical interaction xref: IntAct:EBI-956774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0017624 name: taf9-kpna1 physical interaction xref: IntAct:EBI-956782 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0020532 ! IMA1_HUMAN [Term] id: CCO:I0017625 name: taf9-kpna6-1 physical interaction xref: IntAct:EBI-956790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0020529 ! IMA7_HUMAN [Term] id: CCO:I0017626 name: q8n8b7-atxn1 physical interaction xref: IntAct:EBI-956854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057515 ! TFSC1_HUMAN [Term] id: CCO:I0017627 name: c1orf94-atxn1 physical interaction xref: IntAct:EBI-956862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063009 ! CA094_HUMAN [Term] id: CCO:I0017628 name: atxn1-q86uw1-1 physical interaction xref: IntAct:EBI-956870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063222 ! OSTA_HUMAN [Term] id: CCO:I0017629 name: atxn1-flj12529-1 physical interaction xref: IntAct:EBI-956894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062890 ! CPSF7_HUMAN [Term] id: CCO:I0017630 name: atxn1-c1orf94-1 physical interaction xref: IntAct:EBI-956902 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063009 ! CA094_HUMAN [Term] id: CCO:I0017631 name: npm_alk-pkc physical interaction xref: IntAct:EBI-970373 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005610 ! PLCG1_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0014973 ! EPHA1_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN [Term] id: CCO:I0017632 name: hsp-60-npm_alk physical interaction xref: IntAct:EBI-970381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN [Term] id: CCO:I0017633 name: grb2-npm_alk physical interaction xref: IntAct:EBI-970388 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:I0017634 name: stat3-npm_alk physical interaction xref: IntAct:EBI-970393 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:I0017635 name: irs1-npm_alk physical interaction xref: IntAct:EBI-970398 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:I0017636 name: eif4b-npm_alk physical interaction xref: IntAct:EBI-970403 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0050510 ! IF4B_HUMAN [Term] id: CCO:I0017637 name: epha1-npm_alk physical interaction xref: IntAct:EBI-970408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0014973 ! EPHA1_HUMAN [Term] id: CCO:I0017638 name: ephb3-npm_alk physical interaction xref: IntAct:EBI-970413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0014968 ! EPHB3_HUMAN [Term] id: CCO:I0017639 name: map3k1-npm_alk physical interaction xref: IntAct:EBI-970418 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN [Term] id: CCO:I0017640 name: hrmt1l1-ncoa6-1 physical interaction comment: interaction detected by GST pull down. xref: IntAct:EBI-78697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:I0017641 name: cd22-lyn-1 physical interaction comment: Complex formation on B-cell stimulation xref: IntAct:EBI-79477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017642 name: lyn-cd22-1 physical interaction comment: Direct binding of p56lyn to CD22 xref: IntAct:EBI-79888 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017643 name: p55g-cd19-1 physical interaction comment: Interaction of CD19 with p85 Pi-3K demonstrated by co-immunopreciptiation xref: IntAct:EBI-79912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026600 ! P55G_HUMAN relationship: has_participant CCO:B0055035 ! CD19_HUMAN [Term] id: CCO:I0017644 name: hadh2-app-2 physical interaction comment: amyloid beta -ERAB crosslinking xref: IntAct:EBI-79993 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063213 ! HCD2_HUMAN [Term] id: CCO:I0017645 name: dnmt3b-ubl1-3 colocalization xref: IntAct:EBI-80242 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:I0017646 name: rps6ka4-mapk14 physical interaction comment: Interaction between p38alpha and Rsk-B confirmed by co-immunoprecipitation xref: IntAct:EBI-73988 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005629 ! KS6A4_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN [Term] id: CCO:I0017647 name: eif4e-4ebp1 physical interaction comment: Regulation of human eIF4E by 4E-BP1: binding analysis using surface plasmon resonance xref: IntAct:EBI-74102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:I0017648 name: hrmt1l1-esr1-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0017649 name: hrmt1l1-esr2-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0058084 ! ESR2_HUMAN [Term] id: CCO:I0017650 name: hrmt1l1-pgr-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78555 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0054904 ! PRGR_HUMAN [Term] id: CCO:I0017651 name: hrmt1l1-thrb-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0054979 ! THB_HUMAN [Term] id: CCO:I0017652 name: hrmt1l1-rxra-1 physical interaction comment: Interaction detected by GST-pulldown. xref: IntAct:EBI-78612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0024886 ! RXRA_HUMAN [Term] id: CCO:I0017653 name: hrmt1l1-ppara-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0055786 ! PPARA_HUMAN [Term] id: CCO:I0017654 name: esr1-hrmt1l1-2 physical interaction comment: Regions of ESR1 important in the interaction detected by GST pull down. xref: IntAct:EBI-78636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0017655 name: esr1-hrmt1l1-3 physical interaction comment: Regions of PRMT2 involved in the interaction detected by GST pull down. xref: IntAct:EBI-78641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0017656 name: hrmt1l1-hrmt1l1-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN [Term] id: CCO:I0017657 name: hrmt1l1-scarb1-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0063229 ! SCRB1_HUMAN [Term] id: CCO:I0017658 name: st7-gnb2l1-2 physical interaction comment: Interaction between ST7 and GNB2L1 detected by CoIP. xref: IntAct:EBI-296839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0059369 ! LRP12_HUMAN [Term] id: CCO:I0017659 name: ncor2-hdac1-1 physical interaction comment: Interaction detected by CoIP xref: IntAct:EBI-298014 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:I0017660 name: hdac1-hdac2-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-298035 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0017661 name: ncoa6-crebbp-1 physical interaction comment: Interaction detected by GST pull down assay. xref: IntAct:EBI-286550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:I0017662 name: st7-madhip-2 physical interaction comment: Interaction between ST7 and MADHIP detected by CoIP. xref: IntAct:EBI-296852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054758 ! ZFYV9_HUMAN relationship: has_participant CCO:B0059369 ! LRP12_HUMAN [Term] id: CCO:I0017663 name: hdac2-hdac10-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-297477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005341 ! HDA10_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN [Term] id: CCO:I0017664 name: ncor2-hdac10-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-297505 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005341 ! HDA10_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN [Term] id: CCO:I0017665 name: tesk1-spry4 physical interaction comment: Interaction of Spry4 with testicular protein kinase 1 - Y2H xref: IntAct:EBI-354851 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058614 ! SPY4_HUMAN relationship: has_participant CCO:B0063231 ! TESK1_HUMAN [Term] id: CCO:I0017666 name: spry4-tesk1 physical interaction comment: Interaction of Spry4 with testicular protein kinase 1 - Y2H xref: IntAct:EBI-354881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058614 ! SPY4_HUMAN relationship: has_participant CCO:B0063231 ! TESK1_HUMAN [Term] id: CCO:I0017667 name: myb-nlk physical interaction comment: Interaction of NLK, HIPK2 and MYB in vivo xref: IntAct:EBI-366987 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005632 ! MYB_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:I0017668 name: eif4el3-eif4ebp1-1 physical interaction comment: Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1 xref: IntAct:EBI-398655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054567 ! IF4E2_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:I0017669 name: surf5-q9p086-2 physical interaction comment: Interaction detected by CoIP xref: IntAct:EBI-398806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN [Term] id: CCO:I0017670 name: vcp-der1-sels-1 physical interaction comment: Interaction between VCP, DER1 and SELS detected by CoIP. xref: IntAct:EBI-398982 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058480 ! SELS_HUMAN relationship: has_participant CCO:B0058523 ! DERL1_HUMAN [Term] id: CCO:I0017671 name: gemin5-ddx20-1 physical interaction comment: Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. xref: IntAct:EBI-443675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059141 ! DDX20_HUMAN relationship: has_participant CCO:B0062979 ! GEMI5_HUMAN [Term] id: CCO:I0017672 name: mkl2-srf-1 physical interaction comment: Interaction detected by gel mobility shift assay xref: IntAct:EBI-493043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:I0017673 name: mast2-pclkc-2 physical interaction comment: Interaction of MAST2 and PC-LKC demonstrated by Y2H xref: IntAct:EBI-493811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056876 ! MAST2_HUMAN relationship: has_participant CCO:B0058577 ! PCD24_HUMAN [Term] id: CCO:I0017674 name: casp8-casp8-1 direct interaction comment: Homodimerization of Caspase-8 demonstrated by FRET xref: IntAct:EBI-495149 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0017675 name: dhx9-rela-1 physical interaction comment: dhx9 and rela interaction by gst pull-down using dhx9 as bait. xref: IntAct:EBI-491403 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0017676 name: casp8-caspa-1 direct interaction comment: Heterodimerization of Caspase-8 and Caspase-10 demonstrated by FRET xref: IntAct:EBI-495159 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0058106 ! CASPA_HUMAN [Term] id: CCO:I0017677 name: adra1b-fnlc-1 physical interaction comment: 2-hybrid: bait = human adrenergic receptor alpha 1b, prey= human filamin C xref: IntAct:EBI-490031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN relationship: has_participant CCO:B0041399 ! FLNC_HUMAN [Term] id: CCO:I0017678 name: emd-bclaf1-3 physical interaction comment: far western assay of emerin interacting with btf. xref: IntAct:EBI-490107 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058962 ! BCLF1_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:I0017679 name: raf1-cps1-1 physical interaction comment: Y2H: bait = C-Raf ,prey = CPS1-CPSM_HUMAN xref: IntAct:EBI-537349 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:I0017680 name: raf1-pkm2-2 physical interaction comment: Y2H: bait = C-Raf ,prey = PyK-KPYM_HUMAN xref: IntAct:EBI-537356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:I0017681 name: raf1-ywhab-3 physical interaction comment: Y2H: bait = C-Raf ,prey = 14-3-3beta xref: IntAct:EBI-537363 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0017682 name: tnfr2-traf2 physical interaction comment: Yeast-2-hybrid reveals interaction between the Tumor necrosis factor receptor superfamily member 1B precursor (TNFR2) and TNF receptor associated factor 2 (TRAF2) xref: IntAct:EBI-529856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005535 ! TNR1B_HUMAN [Term] id: CCO:I0017683 name: raf1-cct3-2 physical interaction comment: Y2H: bait = C-Raf ,prey = CCT3-TCPG_HUMAN xref: IntAct:EBI-537377 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0017684 name: raf1-cops3-1 physical interaction comment: Y2H: bait = C-Raf ,prey = SGN3-COP9 complex subunit 3 xref: IntAct:EBI-537384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0017685 name: raf1-cps1-2 physical interaction comment: Y2H: bait = C-Raf ,prey = CPS1-CPSM_HUMAN xref: IntAct:EBI-537398 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:I0017686 name: raf1-cps1-3 physical interaction comment: Y2H: bait = C-Raf ,prey = CPS1-CPSM_HUMAN xref: IntAct:EBI-537405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:I0017687 name: raf1-oip5-3 physical interaction comment: Y2H: bait = C-Raf ,prey = OIP5-OIP5_HUMAN xref: IntAct:EBI-537412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063028 ! OIP5_HUMAN [Term] id: CCO:I0017688 name: raf1-ywhab-4 physical interaction comment: Y2H: bait = C-Raf ,prey = 14-3-3beta xref: IntAct:EBI-537419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0017689 name: gab1-ptpn11-2 physical interaction comment: Interaction of Gab1 and Shp-2 identified by Y2H xref: IntAct:EBI-517742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055765 ! PTN11_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:I0017690 name: tnfrsf6-fadd-14 physical interaction comment: in vivo Co-IP: bait = FAS, prey = FADD xref: IntAct:EBI-518708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0017691 name: ask1-ask1 physical interaction comment: Interaction between the N terminal region and full length mitogen-activated protein kinase kinase kinase 5 protein xref: IntAct:EBI-519041 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005577 ! M3K5_HUMAN [Term] id: CCO:I0017692 name: tnfrsf6-fadd-10 physical interaction comment: yeast 2 hybrid : bait = cytoplasmic domain of FAS, prey = FADD xref: IntAct:EBI-518495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0017693 name: gab1-pik3r1-2 physical interaction comment: Interaction of Gab1 and p85alpha PI-3K identified by Y2H xref: IntAct:EBI-518588 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:I0017694 name: fadd-fadd-2 physical interaction comment: homodimerisation of Fadd by 2 hybrid xref: IntAct:EBI-527090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0017695 name: fadd-fadd-3 physical interaction comment: homodimerisation of Fadd by 2 hybrid xref: IntAct:EBI-527097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0017696 name: apaf1-casp9-1 physical interaction comment: Complex formed between APAF-1, Caspase-9 and Cytochrome C demonstrated by coimmunopreciptiation xref: IntAct:EBI-516795 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN [Term] id: CCO:I0017697 name: apaf1-casp9-2 physical interaction comment: Complex fromed between APAF-1, Caspase-9 and Cytochrome C demonstrated by coimmunopreciptiation xref: IntAct:EBI-516863 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN [Term] id: CCO:I0017698 name: traf6-tiz physical interaction comment: Yeast-2-hybrid reveals interaction between the TNF receptor associated factor 6 (TRAF6) protein and the TRAF6-binding zinc finger protein xref: IntAct:EBI-528186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN [Term] id: CCO:I0017699 name: bca3-prkaca-3 physical interaction comment: Interaction of PKA catalytic domain with BCA3 xref: IntAct:EBI-517054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018543 ! KAPCA_HUMAN relationship: has_participant CCO:B0063233 ! BCA3_HUMAN [Term] id: CCO:I0017700 name: bca3-prkaca-4 physical interaction comment: Interaction of PKA catalytic domain with BCA3 xref: IntAct:EBI-517069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018543 ! KAPCA_HUMAN relationship: has_participant CCO:B0063233 ! BCA3_HUMAN [Term] id: CCO:I0017701 name: dicer1-eif2c1-2 physical interaction xref: IntAct:EBI-528308 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016057 ! I2C1_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0017702 name: ikk_gamma-ikk_alpha physical interaction comment: Coimmunoprecipitation reveals interaction between the NF-kappa-B essential modulator (NEMO) protein and the Inhibitor of nuclear factor kappa-B kinase alpha subunit (IKK_alpha) xref: IntAct:EBI-528357 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0017703 name: ikk_gamma-ikk_beta physical interaction comment: Coimmunoprecipitation reveals interaction between the NF-kappa-B essential modulator (NEMO) protein and the Inhibitor of nuclear factor kappa-B kinase beta subunit (IKK_beta) xref: IntAct:EBI-528399 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0017704 name: cd40-traf3-1 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the CD40 protein and the TNF receptor associated factor 3 (TRAF3) xref: IntAct:EBI-528573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055188 ! TNR5_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN [Term] id: CCO:I0017705 name: gab1-ptpn11-1 physical interaction comment: Interaction of Gab1 and Shp-2 identified by Y2H xref: IntAct:EBI-517697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055765 ! PTN11_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:I0017706 name: gab1-pik3r1-1 physical interaction comment: Interaction of Gab1 and p85alpha PI-3K identified by Y2H xref: IntAct:EBI-517735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:I0017707 name: ifnar2-gnb2l1-3 physical interaction comment: Interaction of IFNAR2 and GNB2L1 identified by coimmunoprecipitation xref: IntAct:EBI-958523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0055406 ! INAR2_HUMAN [Term] id: CCO:I0017708 name: hash1-e2_2-2 direct interaction comment: Interaction between human HASH-1 and E2-2 detected by pulldown xref: IntAct:EBI-957094 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0017709 name: ighg1-fcg2b-9 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942165 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017710 name: ighg1-fcg2b-10 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942192 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017711 name: ighg1-fcg2b-11 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942238 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017712 name: ighg1-fcg2b-12 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942342 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017713 name: ighg1-fcg2b-13 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942352 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017714 name: ighg1-fcg2b-14 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942362 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017715 name: ighg1-fcg2b-15 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942372 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017716 name: ighg1-fcg2b-16 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942382 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017717 name: ighg1-fcg2b-17 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942392 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017718 name: ighg1-fcg2b-18 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942406 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017719 name: syk-pou2af1 colocalization xref: IntAct:EBI-943776 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0056165 ! OBF1_HUMAN [Term] id: CCO:I0017720 name: ighg1-fcg2b-20 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942432 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017721 name: ighg1-fcg2b-21 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942445 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017722 name: ighg1-fcg2b-22 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942458 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017723 name: ighg1-fcg2b-23 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942471 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017724 name: ighg1-fcg2b-24 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942484 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017725 name: ighg1-fcg2b-25 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942497 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017726 name: ighg1-fcg2b-26 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942510 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017727 name: ighg1-fcg2b-27 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942523 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017728 name: ighg1-fcg2b-28 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942536 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017729 name: ighg1-fcg2b-29 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942549 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017730 name: ighg1-fcg2b-30 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942562 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017731 name: ighg1-fcg2b-31 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942575 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017732 name: dnmt1-ezh2-2 physical interaction xref: IntAct:EBI-937400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0017733 name: dnm3a-ezh2 physical interaction xref: IntAct:EBI-937405 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0017734 name: dnm3b-ezh2 physical interaction xref: IntAct:EBI-937422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0017735 name: baz1b-myo1c-1 physical interaction xref: IntAct:EBI-935132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027842 ! MYH1_HUMAN relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0017736 name: ighg1-fcg2b-19 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942419 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017737 name: ighg1-fcg2b-8 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by surface plasmon resonance xref: IntAct:EBI-942150 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0017738 name: mbd2-p66a physical interaction xref: IntAct:EBI-923419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005907 ! P66A_HUMAN relationship: has_participant CCO:B0059065 ! MBD2_HUMAN [Term] id: CCO:I0017739 name: crebbp-nap1l1 physical interaction xref: IntAct:EBI-914380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0017740 name: mst4-mst4-1 physical interaction comment: Homodimer formation by Mst4 demonstrated by Y2H xref: IntAct:EBI-618254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:I0017741 name: rbm8a-ddx48-1 physical interaction comment: pull down: bait=Y14, prey=eif4a3 xref: IntAct:EBI-619108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005223 ! RBM8A_HUMAN relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN [Term] id: CCO:I0017742 name: magoh-ddx48-1 physical interaction comment: pull down: bait=magoh, prey=eif4a3 xref: IntAct:EBI-619113 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0063234 ! MGN_HUMAN [Term] id: CCO:I0017743 name: zn655-vav1-1 physical interaction comment: Interaction between ZN655 (VIK) and VAV1 identified by Y2H xref: IntAct:EBI-625537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005578 ! ZN655_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:I0017744 name: cdc42-arhgap1-1 direct interaction comment: X-Ray: crystal of cdc42 with P50RhoGAP xref: IntAct:EBI-602776 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN [Term] id: CCO:I0017745 name: epor-socs2-3 physical interaction comment: Interaction between human EpoR and SOCS2 demonstrated by MAPPIT xref: IntAct:EBI-617778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0017746 name: dyrk1b-dcohm-1 physical interaction comment: Interaction between DYRK1B and DCOHM identified by Y2H xref: IntAct:EBI-634299 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058656 ! PHS2_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0017747 name: cdc42bpa -rhoq-1 physical interaction comment: Interaction between CDC42BPA and RHOQ demonstrated by GST pulldown xref: IntAct:EBI-689220 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055081 ! RHOQ_HUMAN relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0017748 name: cdc42bpg -rhoq-1 physical interaction comment: Interaction between CDC42BPG and RHOQ demonstrated by GST pulldown xref: IntAct:EBI-689235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055081 ! RHOQ_HUMAN relationship: has_participant CCO:B0056729 ! MRCKG_HUMAN [Term] id: CCO:I0017749 name: atx2-cnsa3 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the ataxin-2 protein and endophilin--A3 protein xref: IntAct:EBI-697725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0017750 name: atx2-cnsa1-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the ataxin-2 protein and endophilin-A1 protein xref: IntAct:EBI-697832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0017751 name: atx2-cnsa3-2 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the ataxin-2 protein and endophilin--A3 protein xref: IntAct:EBI-697841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0017752 name: cnsa1-cnsa1-1 physical interaction comment: Coimuunoprecipitation analysis reveals homotypic interaction of the endophilin-A1 protein xref: IntAct:EBI-697992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0017753 name: cnsa1-cnsa3-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the endophilin-A1 protein and endophilin-A3 protein xref: IntAct:EBI-697999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0017754 name: cnsa3-cnsa2-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the endophilin-A3 protein and endophilin-A2 protein xref: IntAct:EBI-698006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0017755 name: cnsa3-cnsa3-1 physical interaction comment: Coimmunoprecipitation analysis reveals homotypic interaction of the endophilin-A3 protein xref: IntAct:EBI-698013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0017756 name: cdc42bpg -cdc42-1 physical interaction comment: Interaction between CDC42BPG and CDC42 demonstrated by GST pulldown xref: IntAct:EBI-689123 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0056729 ! MRCKG_HUMAN [Term] id: CCO:I0017757 name: cdc42bpa -cdc42-1 physical interaction comment: Interaction between CDC42BPA and CDC42 demonstrated by GST pulldown xref: IntAct:EBI-689161 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0017758 name: adra1d-fnlc-1 physical interaction comment: 2-hybrid: bait = human adrenergic receptor alpha 1d, prey= human filamin C xref: IntAct:EBI-490009 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038265 ! ADA1D_HUMAN relationship: has_participant CCO:B0041399 ! FLNC_HUMAN [Term] id: CCO:I0017759 name: wrn-fen1-2 direct interaction comment: Pull-down: bait = WRN, prey = FEN-1 xref: IntAct:EBI-707684 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0017760 name: raf1-oip5-2 physical interaction comment: Y2H: bait = C-Raf ,prey = OIP5-OIP5_HUMAN xref: IntAct:EBI-537370 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063028 ! OIP5_HUMAN [Term] id: CCO:I0017761 name: wrn-fen1-9 physical interaction comment: FEN-1 is crosslinked with WRN-holliday junction complex in vitro xref: IntAct:EBI-708394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0017762 name: atxn7-trrap-5 physical interaction comment: FLAG pulldown reveals interaction between Ataxin 7 protein and TRRAP, TAF10 the GCN5 protein xref: IntAct:EBI-708530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0017763 name: ptprn-ptprt-1 physical interaction comment: Y2H: bait = IA-2 intracellular domain, prey = PTP rho xref: IntAct:EBI-728216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023006 ! PTPRT_HUMAN relationship: has_participant CCO:B0025847 ! PTPRN_HUMAN [Term] id: CCO:I0017764 name: gan-map1b-1 physical interaction comment: Colocalisation analysis reveals interaction between the Gigaxonin protein and MAP1B protein xref: IntAct:EBI-764628 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055380 ! MAP1B_HUMAN relationship: has_participant CCO:B0063005 ! GAN_HUMAN [Term] id: CCO:I0017765 name: pim1-bmx-5 physical interaction comment: Interaction between PIM1 and BMX identified by coimmunoprecipitation xref: IntAct:EBI-783025 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005923 ! BMX_HUMAN relationship: has_participant CCO:B0022781 ! PIM1_HUMAN [Term] id: CCO:I0017766 name: hspcb-raf1-1 physical interaction comment: Interaction between HSPCB and RAF1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-974419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0017767 name: pum2-dazl1-4 physical interaction xref: IntAct:EBI-998232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:I0017768 name: dazl1-pum2-4 physical interaction xref: IntAct:EBI-998239 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:I0017769 name: arhgap24-flna-1 physical interaction comment: Interaction between ARHGAP24 and FLNA identified by Y2H xref: IntAct:EBI-988773 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0017770 name: arhgap24-cdc42-1 physical interaction comment: ARHGAP24 stimulates the GTPase activity of CDC42 xref: IntAct:EBI-989043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0017771 name: arhgap24-rac1-1 physical interaction comment: ARHGAP24 stimulates the GTPase activity of RAC1 xref: IntAct:EBI-989128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0017772 name: arf6-atp6v1c1-5 physical interaction comment: Interaction between Arf6 and Atp6v1c1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1003831 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055616 ! ARF6_HUMAN relationship: has_participant CCO:B0063235 ! VATC1_HUMAN [Term] id: CCO:I0017773 name: tmed10-psen1-3 physical interaction xref: IntAct:EBI-998747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0017774 name: tmed10-ncstn-2 physical interaction xref: IntAct:EBI-998761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058062 ! NICA_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0017775 name: tmed10-psenen-2 physical interaction xref: IntAct:EBI-998770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058989 ! PEN2_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0017776 name: casp2-raidd-pidd physical interaction comment: Coimmunoprecipitation assay reveals interaction between CASP2, PIDDand RAIDD proteins xref: IntAct:EBI-995265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0017777 name: casp2-raidd-pidd-1 physical interaction comment: Coimmunoprecipitation assay reveals interaction between CASP2, PIDDand RAIDD proteins xref: IntAct:EBI-995271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0017778 name: casp2-raidd-pidd-2 physical interaction comment: Coimmunoprecipitation assay reveals interaction between CASP2, PIDDand RAIDD proteins xref: IntAct:EBI-995278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN [Term] id: CCO:I0017779 name: hsf1-mk2-1 phosphorylation xref: IntAct:EBI-993354 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0026467 ! HSF1_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:I0017780 name: ddx58-mavs-1 physical interaction xref: IntAct:EBI-995369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057158 ! MAVS_HUMAN relationship: has_participant CCO:B0063236 ! DDX58_HUMAN [Term] id: CCO:I0017781 name: ikbke-mavs-1 physical interaction xref: IntAct:EBI-995415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:I0017782 name: chuk-mavs-1 physical interaction xref: IntAct:EBI-995424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:I0017783 name: ikbkb-mavs-1 physical interaction xref: IntAct:EBI-995437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0057158 ! MAVS_HUMAN [Term] id: CCO:I0017784 name: itgav-itgb3-1 direct interaction comment: Crystal structure of the extracellular segment of integrin alphavbeta3 xref: IntAct:EBI-1031956 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026218 ! ITAV_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0017785 name: tradd-traf2-3 direct interaction comment: Crystal structure of the complex between the n-terminal domain of tradd and the traf domain of traf2 xref: IntAct:EBI-1029532 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0017786 name: il6st-lif-1 direct interaction comment: Crystal structure of leukemia inhibitory factor in complex with gp130 xref: IntAct:EBI-1037207 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0025184 ! IL6RB_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN [Term] id: CCO:I0017787 name: nfkb1-nfkbia-1 physical interaction comment: I-kappa-b-alpha-nf-kappa-b complex xref: IntAct:EBI-1027430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0017788 name: il4-il4r-1 direct interaction comment: Interleukin-4 / receptor alpha chain complex xref: IntAct:EBI-1027723 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0055171 ! IL4RA_HUMAN [Term] id: CCO:I0017789 name: apaf1-casp9-5 direct interaction comment: Apaf-1 card in complex with prodomain of procaspase-9 xref: IntAct:EBI-1027774 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0054371 ! APAF_HUMAN [Term] id: CCO:I0017790 name: hba1-hbb-12 direct interaction comment: Deoxygenated structure of a distal pocket hemoglobin mutant xref: IntAct:EBI-1027836 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0017791 name: cplx1-snap25-1 physical interaction comment: Three-dimensional structure of the complexin-snare complex xref: IntAct:EBI-1032873 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055598 ! SNP25_HUMAN [Term] id: CCO:I0017792 name: itgav-itgb3-2 direct interaction comment: Crystal structure of the extracellular segment of integrin alpha vbeta3 bound to mn2+ xref: IntAct:EBI-1033176 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026218 ! ITAV_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0017793 name: taf12-taf4-1 direct interaction comment: Crystal structure of the human taf4-taf12 (tafii135-tafii20) complex xref: IntAct:EBI-1034289 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0018582 ! TAF12_HUMAN relationship: has_participant CCO:B0054305 ! TAF4_HUMAN [Term] id: CCO:I0017794 name: fga-fgb-1 physical interaction comment: Crystal structure of recombinant human fibrinogen fragment d xref: IntAct:EBI-1034460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054865 ! FIBA_HUMAN relationship: has_participant CCO:B0054866 ! FIBB_HUMAN relationship: has_participant CCO:B0054867 ! FIBG_HUMAN [Term] id: CCO:I0017795 name: cxcr4-myh9-1 physical interaction comment: Interaction between human CXCR4 and MYH9 detected by pulldown xref: IntAct:EBI-1126706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:I0017796 name: ccr5-myh9-1 physical interaction comment: Interaction between human CCR5 and MYH9 detected by pulldown xref: IntAct:EBI-1127070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0055474 ! CCR5_HUMAN [Term] id: CCO:I0017797 name: cftr-slc9a3r2-2 physical interaction xref: IntAct:EBI-1149856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025069 ! NHRF2_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN [Term] id: CCO:I0017798 name: cftr-slc9a3r2-3 physical interaction xref: IntAct:EBI-1149870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025069 ! NHRF2_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN [Term] id: CCO:I0017799 name: fyn-htr6-3 direct interaction comment: Interaction between HTR6 and FYN identified by pulldown xref: IntAct:EBI-1182257 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:I0017800 name: hsp90aa1-mmp2 physical interaction comment: MMP2 coimmunoprecipitates with HSP90alpha xref: IntAct:EBI-1176756 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0024617 ! MMP2_HUMAN [Term] id: CCO:I0017801 name: zbtb16-q8iub0-2 direct interaction comment: GST-PLZF pulls down CCS-3 in vitro xref: IntAct:EBI-1189475 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN relationship: has_participant CCO:B0063237 ! Q8IUB0_HUMAN [Term] id: CCO:I0017802 name: ar-myst2-2 direct interaction comment: The human androgen receptor pulls down the LBD of human HBO1 (MYST2) xref: IntAct:EBI-1179565 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0017803 name: myst2-ar direct interaction comment: Human HBO1 (MYST2) C-terminal region pulls down the human androgen receptor xref: IntAct:EBI-1179586 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0017804 name: cbfa2t2-znf652-3 physical interaction comment: CBFA2T2 interacts weakly ZNF652 in HEK-293t lysates as shown by coimmunoprecipitation xref: IntAct:EBI-1190319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054482 ! MTG8R_HUMAN relationship: has_participant CCO:B0059300 ! ZN652_HUMAN [Term] id: CCO:I0017805 name: rfc2-rfc3-3 physical interaction comment: Reconstitution of the RFC complex in the absence of RFC1 p140 subunit xref: IntAct:EBI-1170086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0017806 name: mt2a-spink7 physical interaction comment: FLAG-ECRG2 coimmunoprecipitates with HA-MT2A in HEK-293 cell lysates xref: IntAct:EBI-1182621 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0062971 ! ISK7_HUMAN [Term] id: CCO:I0017807 name: spink7-mt2a-2 physical interaction comment: HA-MT2A coimmunoprecipitates with FLAG-ECRG2 in HEK-293 cell lysates xref: IntAct:EBI-1182638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0062971 ! ISK7_HUMAN [Term] id: CCO:I0017808 name: bak1-mcl1 physical interaction xref: IntAct:EBI-1171033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005420 ! BAK_HUMAN relationship: has_participant CCO:B0055785 ! MCL1_HUMAN [Term] id: CCO:I0017809 name: kdr-nrp1 physical interaction comment: NRP1 coimmunoprecipitates with VEGFR2 from HUVEC lysate xref: IntAct:EBI-1187384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005447 ! NRP1_HUMAN relationship: has_participant CCO:B0055305 ! VGFR2_HUMAN [Term] id: CCO:I0017810 name: med28-grb2-4 direct interaction comment: Interaction between MED28 and Grb2 detected by Far Western xref: IntAct:EBI-1206975 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN [Term] id: CCO:I0017811 name: fyn-med28-1 phosphorylation comment: Phosphorylation of MED28 by FYN xref: IntAct:EBI-1206744 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005468 ! MED28_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0017812 name: gh1-prlr-1 direct interaction comment: The xray structure of a growth hormone-prolactin receptor complex xref: IntAct:EBI-1026085 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054843 ! SOMA_HUMAN relationship: has_participant CCO:B0055053 ! PRLR_HUMAN [Term] id: CCO:I0017813 name: tnfrsf10b-tnfsf10-1 direct interaction comment: Crystal structure of death receptor 5 (dr5) bound to apo2l-trail xref: IntAct:EBI-1028559 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN [Term] id: CCO:I0017814 name: bckdha-bckdhb-1 direct interaction comment: Human branched-chain alpha-keto acid dehydrogenase xref: IntAct:EBI-1029086 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0017815 name: cd86-ctla4-1 direct interaction comment: Crystal structure of the ctla-4/b7-2 complex xref: IntAct:EBI-1031013 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055346 ! CD86_HUMAN relationship: has_participant CCO:B0063145 ! CTLA4_HUMAN [Term] id: CCO:I0017816 name: icam3-itgal-1 direct interaction comment: Structural basis of icam recognition by integrin alpahlbeta2 revealed in the complex structure of binding domains of icam-3 and alphalbeta2 at 1.65 a xref: IntAct:EBI-1041885 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0050202 ! ITAL_HUMAN relationship: has_participant CCO:B0063239 ! ICAM3_HUMAN [Term] id: CCO:I0017817 name: disc1-eif3s3-5 physical interaction xref: IntAct:EBI-1105758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0017818 name: disc1-pde4b physical interaction xref: IntAct:EBI-1106195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0055784 ! PDE4B_HUMAN [Term] id: CCO:I0017819 name: disc1-smarce1 physical interaction xref: IntAct:EBI-1106313 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0017820 name: disc1-snx6 physical interaction xref: IntAct:EBI-1106343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0026583 ! SNX6_HUMAN [Term] id: CCO:I0017821 name: disc1-ywhaz physical interaction xref: IntAct:EBI-1106581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005591 ! DISC1_HUMAN [Term] id: CCO:I0017822 name: cftr-nhe2-1 physical interaction xref: IntAct:EBI-1108003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0020193 ! SL9A2_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN [Term] id: CCO:I0017823 name: plxnb1-rnd1-1 physical interaction xref: IntAct:EBI-1111479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030278 ! RND1_HUMAN relationship: has_participant CCO:B0054451 ! PLXB1_HUMAN [Term] id: CCO:I0017824 name: plxnb1-rnd3-1 physical interaction xref: IntAct:EBI-1111547 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030277 ! RND3_HUMAN relationship: has_participant CCO:B0054451 ! PLXB1_HUMAN [Term] id: CCO:I0017825 name: nucleolin-myh9-2 physical interaction comment: Interaction between human Nucleolin and MYH9 detected by western xref: IntAct:EBI-1166832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0017826 name: mt2a-prkd1 physical interaction comment: PKCmu coimmunoprecipitates with MT 2A in LNCaP cells xref: IntAct:EBI-1181143 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:I0017827 name: qsk-ywhaz-4 direct interaction comment: Interaction between 14-3-3Z and QSK identified by pulldown xref: IntAct:EBI-1181856 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:I0017828 name: raf1-ywhaz-2 direct interaction comment: Interaction between 14-3-3Z and RAF1 identified by pulldown xref: IntAct:EBI-1181878 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0017829 name: zbtb16-q8iub0-3 physical interaction comment: GST-PLZF coimmunoprecipitates CCS-3 in SiHa cell lysates xref: IntAct:EBI-1189501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN relationship: has_participant CCO:B0063237 ! Q8IUB0_HUMAN [Term] id: CCO:I0017830 name: med28-fyn-1 physical interaction comment: Interaction between MED28 (Magicin) and Fyn identified by Y2H xref: IntAct:EBI-1206640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005468 ! MED28_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0017831 name: fyn-med28-2 physical interaction comment: Interaction between Fyn and MED28 identified by GST pulldown xref: IntAct:EBI-1206762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005468 ! MED28_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0017832 name: src-med28-1 physical interaction comment: Interaction between Src and MED28 identified by GST pulldown xref: IntAct:EBI-1206815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN [Term] id: CCO:I0017833 name: sos1-grb2-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0017834 name: sos1-pacsin3-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0017835 name: sos1-snx9-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005559 ! SNX9_HUMAN [Term] id: CCO:I0017836 name: sos1-snag1-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0063241 ! SNX18_HUMAN [Term] id: CCO:I0017837 name: sos2-grb2-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN [Term] id: CCO:I0017838 name: sos2-pacsin3-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298203 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005666 ! SOS2_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0017839 name: sos2-snx9-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005559 ! SNX9_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN [Term] id: CCO:I0017840 name: sos2-snag1-1 physical interaction comment: Interaction detected by pull down. xref: IntAct:EBI-298218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005666 ! SOS2_HUMAN relationship: has_participant CCO:B0063241 ! SNX18_HUMAN [Term] id: CCO:I0017841 name: nfkb1-pdcd11-1 physical interaction comment: Interaction between NFKB1 and PDCD11 detected by Y2H. xref: IntAct:EBI-300038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0062995 ! RRP5_HUMAN [Term] id: CCO:I0017842 name: cd5-cd72-1 physical interaction comment: Interaction detected by FACS xref: IntAct:EBI-307941 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050006 ! CD72_HUMAN relationship: has_participant CCO:B0054901 ! CD5_HUMAN [Term] id: CCO:I0017843 name: hck-elmo1-3 physical interaction comment: Interaction between HCK and ELMO1 detected by GST pull down xref: IntAct:EBI-346460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0017844 name: il2rg-il4r-1 physical interaction comment: interaction of IL2R gamma chain with IL4R and IL4. xref: IntAct:EBI-367058 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0055171 ! IL4RA_HUMAN relationship: has_participant CCO:B0055246 ! IL2RG_HUMAN [Term] id: CCO:I0017845 name: il4r-il4-1 physical interaction comment: interaction of IL4R and IL4 by co-ip and radio-affnity labelling. xref: IntAct:EBI-367101 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0055171 ! IL4RA_HUMAN [Term] id: CCO:I0017846 name: il4r-il4-2 physical interaction comment: interaction of IL4R with IL4 and IL2Rgamma xref: IntAct:EBI-367105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0055171 ! IL4RA_HUMAN relationship: has_participant CCO:B0055246 ! IL2RG_HUMAN [Term] id: CCO:I0017847 name: wrn-parp1-1 physical interaction comment: Flag pull-down: bait= WRN, prey = WRN xref: IntAct:EBI-372004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0017848 name: vcp-der1-sels-2 colocalization comment: VCP co-localises with DER1 and SELS in COS cells. xref: IntAct:EBI-399051 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0058480 ! SELS_HUMAN relationship: has_participant CCO:B0058523 ! DERL1_HUMAN [Term] id: CCO:I0017849 name: tr-crsp6-1 physical interaction comment: interaction detected by GST-pull down assay. xref: IntAct:EBI-399687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0054978 ! THA_HUMAN [Term] id: CCO:I0017850 name: q9nwa0-vdrip-2 physical interaction comment: Interaction detected by FLAG-IP. xref: IntAct:EBI-400043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN [Term] id: CCO:I0017851 name: elmo1-dock1-1 physical interaction comment: Elmo1 coimunoprecipitates with Dock180 xref: IntAct:EBI-446926 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0017852 name: gga1-arf1-1 physical interaction comment: two hybrid interaction between GGA1GAT domain and ARF xref: IntAct:EBI-447170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005670 ! GGA1_HUMAN relationship: has_participant CCO:B0015288 ! ARF1_HUMAN [Term] id: CCO:I0017853 name: gga1-tsg101-1 physical interaction comment: two hybrid interaction between GGA1 VHS-GAT fragment and TSG101 xref: IntAct:EBI-447200 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0005670 ! GGA1_HUMAN [Term] id: CCO:I0017854 name: elmo1-dock1-2 physical interaction comment: Interaction detected by Flag CoIP, bait= flag elmo1, prey = dock 180 xref: IntAct:EBI-447537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0017855 name: elmo1-dock1-3 physical interaction comment: Interaction detected by Flag CoIP, bait= flag elmo1, prey = dock 180 xref: IntAct:EBI-447571 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0017856 name: elmo1-dock1-4 physical interaction comment: Interaction detected by Flag CoIP, bait= flag elmo1, prey = dock 180 xref: IntAct:EBI-447576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0017857 name: peli1-irak1-1 physical interaction comment: Complex formed between IRAK1, PELI1 IRAK4 and TRAF6 identified by co-immunoprecipitation xref: IntAct:EBI-448387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN relationship: has_participant CCO:B0063242 ! PELI1_HUMAN [Term] id: CCO:I0017858 name: peli1-irak1-2 physical interaction comment: Complex formed between TAK1, TAB1, and TRAF6 identified by co-immunoprecipitation xref: IntAct:EBI-448395 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0063243 ! TAB3_HUMAN [Term] id: CCO:I0017859 name: rac1-dock1-3 physical interaction comment: Interaction detected by co IP, bait = human dock 180, prey =human Rac1 xref: IntAct:EBI-448734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0017860 name: elmo1-dock1-5 physical interaction comment: Interaction detected by Flag CoIP, bait= flag dock180, prey = GFP-Elmo1 xref: IntAct:EBI-448740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0017861 name: cd22-ptpn6-2 physical interaction comment: Interaction between CD22 and PTP-1C detected by co-immunoprecipitation xref: IntAct:EBI-492022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017862 name: mast2-pclkc-1 physical interaction comment: Interaction of MAST2 and PC-LKC demonstrated by Y2H xref: IntAct:EBI-493776 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056876 ! MAST2_HUMAN relationship: has_participant CCO:B0058577 ! PCD24_HUMAN [Term] id: CCO:I0017863 name: tnfrsf6-fadd-2 physical interaction comment: Interaction between FasLR and FADD identified by Y2H xref: IntAct:EBI-494861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0017864 name: fadd-fadd-1 physical interaction comment: FADD dimerization demonstrated by Y2H xref: IntAct:EBI-494890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0017865 name: tnfrsf6-tnfrsf6-1 physical interaction comment: Multimerization between FasLRmolecules identified by Y2H xref: IntAct:EBI-494924 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN [Term] id: CCO:I0017866 name: tnfrsf6-fadd-5 physical interaction comment: Interaction between FasLR and FADD identified by Y2H xref: IntAct:EBI-494966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0017867 name: tnfsf6-tnfrsf6-1 physical interaction comment: FAS DISC complex shown by immunoprecipitation (anti-Flag FasL): FasL, Fas, FADD, caspase-8 xref: IntAct:EBI-514619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0017868 name: bca3-prkaca-1 physical interaction comment: Interaction of PKA catalytic domain with BCA3 xref: IntAct:EBI-517040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018543 ! KAPCA_HUMAN relationship: has_participant CCO:B0063233 ! BCA3_HUMAN [Term] id: CCO:I0017869 name: tac1-blys-2 physical interaction comment: The B-lymphocyte stimulator (BlyS) protein interacts with the tumor necrosis factor receptor superfamily member TAC1 xref: IntAct:EBI-519371 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0017870 name: bid-bak1-1 direct interaction comment: interaction detected by CoIP xref: IntAct:EBI-519752 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005420 ! BAK_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN [Term] id: CCO:I0017871 name: casp9-apaf1-1 physical interaction comment: GST pull-down : bait = Apaf-1, prey = caspase 9 xref: IntAct:EBI-520618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0054371 ! APAF_HUMAN [Term] id: CCO:I0017872 name: birc7-casp9-3 physical interaction comment: Fluorescence: FAM peptide = caspase 9, prey = ML-IAP BIR domain xref: IntAct:EBI-523706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN [Term] id: CCO:I0017873 name: birc7-prss25-2 physical interaction comment: Fluorescence: FAM peptide = htrA2, prey = ML-IAP BIR domain xref: IntAct:EBI-523720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0063244 ! HTRA2_HUMAN [Term] id: CCO:I0017874 name: birc7-diablo-4 physical interaction comment: Fluorescence: FAM peptide = SMAC, prey = ML-IAP BIR domain xref: IntAct:EBI-523732 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0017875 name: birc4-prss25-3 physical interaction comment: Fluorescence: FAM peptide = htrA2, prey = X-IAP BIR3 domain xref: IntAct:EBI-523744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0063244 ! HTRA2_HUMAN [Term] id: CCO:I0017876 name: birc4-diablo-5 physical interaction comment: Fluorescence: FAM peptide = SMAC, prey = X-IAP BIR3 domain xref: IntAct:EBI-523760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0017877 name: birc4-casp9-4 physical interaction comment: Fluorescence: FAM peptide = caspase 9, prey = X-IAP BIR3 domain xref: IntAct:EBI-523784 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0017878 name: mll-mll-1 physical interaction comment: Interaction of human MLL, as detected by Y2H. xref: IntAct:EBI-591413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:I0017879 name: ccr1-plp2-2 physical interaction comment: Interaction of CCR1 and PLP2 detected by CoIP xref: IntAct:EBI-608366 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055740 ! PLP2_HUMAN [Term] id: CCO:I0017880 name: rbpsuh-skiip-2 physical interaction comment: SKIP interacts with CBF-1, as detected by GST pull-down. xref: IntAct:EBI-632777 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0048571 ! SNW1_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN [Term] id: CCO:I0017881 name: smarca4-arid1a-1 physical interaction xref: IntAct:EBI-679101 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0017882 name: arid1a-smarca4-5 physical interaction xref: IntAct:EBI-679497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0017883 name: arid1a--smarca2-1 physical interaction xref: IntAct:EBI-679789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0017884 name: smarca4-arid1b-1 physical interaction xref: IntAct:EBI-679978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:I0017885 name: arid1b-smarca4-1 physical interaction xref: IntAct:EBI-680030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:I0017886 name: arid1b-smarca2-2 physical interaction xref: IntAct:EBI-680201 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:I0017887 name: atxn7-trrap physical interaction comment: Coimmunoprecipitation reveals interaction between Ataxin 7 protein and TRRAP, TAF10 the GCN5 protein xref: IntAct:EBI-708408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0017888 name: trrap-1-atxn7 physical interaction comment: Coimmunoprecipitation reveals interaction between TRRAPprotein and Ataxin 7 , TAF10 the GCN5 protein xref: IntAct:EBI-708415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0017889 name: pmaip1-bclw-1 direct interaction comment: Interaction between Pmaip1 and BCL-w induced by mutation xref: IntAct:EBI-709316 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006340 ! APR_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0017890 name: gck-pfkfb1-1 direct interaction comment: Interaction between GCK and PFKFB1 identified by phage display xref: IntAct:EBI-709993 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0018508 ! HXK4_HUMAN relationship: has_participant CCO:B0033471 ! F261_HUMAN [Term] id: CCO:I0017891 name: gck-gckr-3 direct interaction comment: Interaction between GCK and GCKR1 identified by phage display xref: IntAct:EBI-710326 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0018508 ! HXK4_HUMAN relationship: has_participant CCO:B0063245 ! GCKR_HUMAN [Term] id: CCO:I0017892 name: plzf-pml-5 physical interaction comment: Interaction between PLZF and PML detected by Y2H xref: IntAct:EBI-779780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0017893 name: plzf-pml-7 physical interaction comment: Interaction between PLZF and PML detected by Y2H xref: IntAct:EBI-779799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0017894 name: plzf-plzf-2 physical interaction comment: PLZF homodimerisation detected by Y2H xref: IntAct:EBI-779808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0017895 name: adam15-pacsin3-3 physical interaction xref: IntAct:EBI-78019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005909 ! ADA15_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0017896 name: adam9-sh3gl2-3 physical interaction xref: IntAct:EBI-78026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0017897 name: cd22-ptpn6-1 physical interaction comment: Interaction between CD22 and PTP-1C detected by co-immunoprecipitation xref: IntAct:EBI-78259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017898 name: ptpn6-cd22-1 physical interaction comment: Complex formation on B-cell receptor stimulation with IgM xref: IntAct:EBI-78301 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017899 name: cbx5-trim28-2 physical interaction comment: Interaction determined by GST pull down assay. xref: IntAct:EBI-78315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:I0017900 name: cbx5-trim28-3 physical interaction comment: Interaction detected by GST pull down assay. xref: IntAct:EBI-78320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:I0017901 name: accn2-prkcabp-1 physical interaction xref: IntAct:EBI-79188 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0055639 ! ACCN2_HUMAN [Term] id: CCO:I0017902 name: accn2-prkcabp-3 colocalization xref: IntAct:EBI-79215 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0055639 ! ACCN2_HUMAN [Term] id: CCO:I0017903 name: app-chrna7-1 colocalization comment: app-chrna7 colocalisation. xref: IntAct:EBI-79351 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0055310 ! ACHA7_HUMAN [Term] id: CCO:I0017904 name: ptpn-6-cd22-2 physical interaction comment: Complex formation on B-cell receptor stimulation with peroxyvanadate xref: IntAct:EBI-79386 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0005610 ! PLCG1_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017905 name: cd22-ksyk-1 physical interaction comment: Interaction of CD22 and Syk confirmed by coimmunoprecipitation xref: IntAct:EBI-79420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017906 name: cd22-plcg1 physical interaction comment: Interaction of CD22 and PLC-gamma confirmed by coimmunoprecipitation xref: IntAct:EBI-79440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005610 ! PLCG1_HUMAN relationship: has_participant CCO:B0063228 ! CD22_HUMAN [Term] id: CCO:I0017907 name: ephb1-grb10-3 physical interaction comment: ELK-GRB10and GRB2 form a coprecipitable complex. xref: IntAct:EBI-80335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0014969 ! EPHB1_HUMAN relationship: has_participant CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:I0017908 name: dnmt3l-hdac1 physical interaction xref: IntAct:EBI-904634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0037714 ! DNM3L_HUMAN [Term] id: CCO:I0017909 name: lrp6-cmg2-1 colocalization xref: IntAct:EBI-911003 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0025967 ! LRP6_HUMAN relationship: has_participant CCO:B0063007 ! ANTR2_HUMAN [Term] id: CCO:I0017910 name: nck1-waspip-2 physical interaction comment: GST Pull-down: bait= human Nck, prey = human WIP xref: IntAct:EBI-919803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0063008 ! WIPF1_HUMAN [Term] id: CCO:I0017911 name: nck-dnm1-3 physical interaction comment: Co-IP in a leukemia cell line: bait = Nck , prey= dynamin xref: IntAct:EBI-922977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022139 ! DYN1_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN [Term] id: CCO:I0017912 name: hbxap-smarca5 physical interaction xref: IntAct:EBI-926812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:I0017913 name: hbxap-smarca5-1 physical interaction xref: IntAct:EBI-926817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:I0017914 name: disc1-itsn1-2 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ITSN1 protein xref: IntAct:EBI-929234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0017915 name: mx1-trpc6-2 physical interaction comment: Y2H: bait = TRPC6 ARD domains, prey = MxA xref: IntAct:EBI-929413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0062980 ! TRPC6_HUMAN [Term] id: CCO:I0017916 name: leo1-ctnnb1-5 physical interaction xref: IntAct:EBI-932452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:I0017917 name: s100b-s100b-2 physical interaction comment: Homodimerisation of human S100B detected by Y2H xref: IntAct:EBI-945527 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0017918 name: s100b-s100b-3 physical interaction comment: Homodimerisation of human S100B detected by Y2H xref: IntAct:EBI-945534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN [Term] id: CCO:I0017919 name: s100a11-s100a11-1 physical interaction comment: Homodimerisation of human S100A11 detected by Y2H xref: IntAct:EBI-945567 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:I0017920 name: s100b-s100a11-2 physical interaction comment: Interaction between human S100B and S100A11 detected by Y2H xref: IntAct:EBI-945572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:I0017921 name: s100a11-s100b-1 physical interaction comment: Interaction between human S100A11 and S100B detected by Y2H xref: IntAct:EBI-945580 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN [Term] id: CCO:I0017922 name: s100a1-s100a1-1 physical interaction comment: Homodimerisation of human S100A1 detected by Y2H xref: IntAct:EBI-945590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0017923 name: s100a1-s100b-2 physical interaction comment: Interaction between human S100A1 and S100B detected by Y2H xref: IntAct:EBI-945594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0017924 name: ifnar2-gnb2l1-2 physical interaction comment: Interaction of IFNAR2 and GNB2L1 identified by GST pulldown xref: IntAct:EBI-958456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0055406 ! INAR2_HUMAN [Term] id: CCO:I0017925 name: s100b-s100a1-2 physical interaction comment: Interaction between human S100B and S100A1 detected by Y2H xref: IntAct:EBI-959938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0017926 name: pparg-pparbp-1 physical interaction xref: IntAct:EBI-960897 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN [Term] id: CCO:I0017927 name: pxn-rnf5-2 physical interaction xref: IntAct:EBI-963436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0017928 name: pxn-rnf5-3 physical interaction xref: IntAct:EBI-963447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0017929 name: rnf5-pxn-1 physical interaction xref: IntAct:EBI-963454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0017930 name: ptpn6-pilra-2 physical interaction xref: IntAct:EBI-965953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0015779 ! PILRA_HUMAN [Term] id: CCO:I0017931 name: ptpn6-pilra-3 physical interaction xref: IntAct:EBI-966043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0015779 ! PILRA_HUMAN [Term] id: CCO:I0017932 name: ptpn6-pilra-4b physical interaction xref: IntAct:EBI-966055 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0015779 ! PILRA_HUMAN [Term] id: CCO:I0017933 name: tlr2-myd88 colocalization comment: Colocalisation analysis reveals interaction between TLR2 protein and mYD88 protein xref: IntAct:EBI-973714 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0030171 ! TLR2_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0017934 name: rma1-cftr colocalization xref: IntAct:EBI-988724 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0017935 name: stk38-mobk1b-1 physical interaction xref: IntAct:EBI-991340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015584 ! STK38_HUMAN relationship: has_participant CCO:B0024568 ! MOL1B_HUMAN [Term] id: CCO:I0017936 name: mobk1b-stk38-1 physical interaction xref: IntAct:EBI-991394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015584 ! STK38_HUMAN relationship: has_participant CCO:B0024568 ! MOL1B_HUMAN [Term] id: CCO:I0017937 name: rraga-rragc-2 physical interaction xref: IntAct:EBI-992985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0017938 name: rraga-rragd-2 physical interaction xref: IntAct:EBI-992999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0063034 ! RRAGD_HUMAN [Term] id: CCO:I0017939 name: rragc-rraga-5 physical interaction xref: IntAct:EBI-993148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0017940 name: rraga-rragc-4 physical interaction xref: IntAct:EBI-993166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0017941 name: rragc-rraga-6 physical interaction xref: IntAct:EBI-993185 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0017942 name: mk2-hsf1 physical interaction xref: IntAct:EBI-993634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026467 ! HSF1_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:I0017943 name: suv93h1-cbx5-3 colocalization xref: IntAct:EBI-994721 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0017944 name: mll2-ash2l physical interaction xref: IntAct:EBI-996213 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0006000 ! WDR5B_HUMAN relationship: has_participant CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:I0017945 name: mll2-rbq3-3 physical interaction xref: IntAct:EBI-996228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:I0017946 name: mll2-ash2l-1 physical interaction xref: IntAct:EBI-996235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0006000 ! WDR5B_HUMAN relationship: has_participant CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:I0017947 name: arf6-atp6v1c1-6 physical interaction comment: Interaction between Arf6 and Atp6v1c1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-1003847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055616 ! ARF6_HUMAN relationship: has_participant CCO:B0063235 ! VATC1_HUMAN [Term] id: CCO:I0017948 name: casc3-ddx48 physical interaction xref: IntAct:EBI-1008298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005223 ! RBM8A_HUMAN relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0063234 ! MGN_HUMAN relationship: has_participant CCO:B0063246 ! CASC3_HUMAN [Term] id: CCO:I0017949 name: casc3-ddx48-1 physical interaction xref: IntAct:EBI-1008328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0063246 ! CASC3_HUMAN [Term] id: CCO:I0017950 name: hba1-hbb-10 direct interaction comment: Hemoglobin (alpha + met) variant xref: IntAct:EBI-1027502 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0017951 name: hba1-hbb-11 direct interaction comment: Hemoglobin (alpha v1m) mutant xref: IntAct:EBI-1027513 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0017952 name: arhgdia-rhoa-1 direct interaction comment: Crystal structure of the rhoa.gdp-rhogdi complex xref: IntAct:EBI-1028216 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN [Term] id: CCO:I0017953 name: birc4-casp7-1 physical interaction comment: Crystal structure of caspase-7 complexed with xiap xref: IntAct:EBI-1030883 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055530 ! CASP7_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0017954 name: icam1-itgal-1 direct interaction comment: Crystal structure of alphal i domain in complex with icam-1 xref: IntAct:EBI-1035376 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005450 ! ICAM1_HUMAN relationship: has_participant CCO:B0050202 ! ITAL_HUMAN [Term] id: CCO:I0017955 name: birc4-casp9-5 direct interaction comment: Structure of caspase-9 in an inhibitory complex with xiap- bir3 xref: IntAct:EBI-1035811 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0017956 name: sumo1-uble1a-2 physical interaction comment: Sumo e1 activating enzyme sae1-sae2-sumo1-mg-atp complex xref: IntAct:EBI-1037073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN relationship: has_participant CCO:B0006046 ! SAE1_HUMAN relationship: has_participant CCO:B0063247 ! SAE2_HUMAN [Term] id: CCO:I0017957 name: hcrt-hla_dqa1-1 physical interaction comment: Crystal structure of hla-dq0602 in complex with a hypocretin peptide xref: IntAct:EBI-1038032 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054501 ! OREX_HUMAN relationship: has_participant CCO:B0063248 ! HA25_HUMAN relationship: has_participant CCO:B0063249 ! HB25_HUMAN [Term] id: CCO:I0017958 name: nfya-tp53-3 physical interaction xref: IntAct:EBI-1040877 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN [Term] id: CCO:I0017959 name: abl2-rin1-2 physical interaction comment: Interaction between Abl2 and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005385 ! RIN1_HUMAN relationship: has_participant CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:I0017960 name: s100a1-s100p-1 physical interaction xref: IntAct:EBI-1110894 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055155 ! S10A1_HUMAN relationship: has_participant CCO:B0062804 ! S100P_HUMAN [Term] id: CCO:I0017961 name: s100a1-s100a1-4 physical interaction xref: IntAct:EBI-1110904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055155 ! S10A1_HUMAN [Term] id: CCO:I0017962 name: cxcr4-myh9-3 physical interaction comment: Interaction between human CXCR4 and MYH9 detected by pulldown xref: IntAct:EBI-1128028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:I0017963 name: cxcr4-myh9-5 colocalization comment: Colocalisation of human CXCR4 and MYH9 detected by confocal xref: IntAct:EBI-1128996 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:I0017964 name: cd247-cd247 direct interaction comment: NMR solution structure of zeta-zeta (transmembrane domain) xref: IntAct:EBI-1165728 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055130 ! CD3Z_HUMAN [Term] id: CCO:I0017965 name: nucleolin-myh9-3 colocalization comment: Colocalisation of human Nucleolin and MYH9 detected by confocal microscopy xref: IntAct:EBI-1166843 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005733 ! NUCL_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0017966 name: os9-egln1 physical interaction comment: Endogenous PHD2 coimmunoprecipitates with V5-OS-9 xref: IntAct:EBI-1174814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0029351 ! EGLN1_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0017967 name: os9-egln1-1 physical interaction comment: FLAG-HIF-1 alpha and endogenous PHD2 coimmunoprecipitate with V5-OS-9 xref: IntAct:EBI-1174877 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0029351 ! EGLN1_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0017968 name: os9-hif1a physical interaction comment: Induced endogenous HIF-1 alpha coimmunoprecipitates with V5-OS-9 xref: IntAct:EBI-1175038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0017969 name: os9-egln1-2 physical interaction comment: V5-OS-9 coimmunoprecipitated endogenous PHD2 and native HIF-1 alpha xref: IntAct:EBI-1175112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0029351 ! EGLN1_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0017970 name: os9-egln1-3 physical interaction comment: V5-OS-9 coimmunoprecipitated HIF-1alpha-TM and endogenous PHD2 xref: IntAct:EBI-1175199 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0029351 ! EGLN1_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0017971 name: ar-myst2 physical interaction comment: In a yeast two-hybrid assay the human androgen receptor interacts with HBO1 (MYST2) xref: IntAct:EBI-1179513 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0017972 name: rela-aatf-2 physical interaction comment: Che-1 coimmunoprecipitates with p65 xref: IntAct:EBI-1181003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005446 ! AATF_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0017973 name: fyn-htr6-2 physical interaction comment: Interaction between HTR6 and FYN identified by Y2H xref: IntAct:EBI-1182242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:I0017974 name: cacnb3-syt1-1 physical interaction comment: The beta4a A domain is involved in protein-protein interactions. xref: IntAct:EBI-1184672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040103 ! SYT1_HUMAN relationship: has_participant CCO:B0055513 ! CACB3_HUMAN [Term] id: CCO:I0017975 name: eif1a-eif5b-2 direct interaction comment: NMR chemical-shift uppon addition of eIF5B to eIF1A xref: IntAct:EBI-286426 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016435 ! IF1AY_HUMAN relationship: has_participant CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:I0017976 name: eif4e-importinalpha- physical interaction comment: A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E xref: IntAct:EBI-301394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0006012 ! 4ET_HUMAN relationship: has_participant CCO:B0016186 ! IF4E_HUMAN [Term] id: CCO:I0017977 name: ski-madh4-1 physical interaction xref: IntAct:EBI-347291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0055004 ! SKI_HUMAN [Term] id: CCO:I0017978 name: ski-ncor1-1 physical interaction xref: IntAct:EBI-347294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054626 ! NCOR1_HUMAN relationship: has_participant CCO:B0055004 ! SKI_HUMAN [Term] id: CCO:I0017979 name: ski-sin3a-1 physical interaction xref: IntAct:EBI-347297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0055004 ! SKI_HUMAN [Term] id: CCO:I0017980 name: il4r-il4-3 physical interaction comment: IL4R interactions in EBV-transformed B cells xref: IntAct:EBI-367142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0055171 ! IL4RA_HUMAN relationship: has_participant CCO:B0055246 ! IL2RG_HUMAN [Term] id: CCO:I0017981 name: parp1-wrn-2 adp ribosylation comment: Ku70 and ku80 are poly(ADP-ribosyl)ated by PARP-1 xref: IntAct:EBI-372037 is_a: CCO:Y0000032 ! adp ribosylation reaction relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0017982 name: cbfb-p32-1 physical interaction comment: Interaction between CBFB and p32 demonstrated by coimmunoprecipitation xref: IntAct:EBI-389819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:I0017983 name: cbfb-p32-2 physical interaction comment: Interaction between CBFB and p32 confirmed by coimmunoprecipitation xref: IntAct:EBI-389825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:I0017984 name: surf5-q9p086-3 physical interaction comment: Interaction detected by CoIP xref: IntAct:EBI-398844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN [Term] id: CCO:I0017985 name: eea1-rab5b-1 physical interaction comment: interaction of EEA1 with Rab5B detected by Y2H. xref: IntAct:EBI-399417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023553 ! RAB5B_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0017986 name: eea1-rab5a-1 physical interaction comment: Interaction of EEA1 and Rab5a detected by Y2H. xref: IntAct:EBI-399450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023551 ! RAB5A_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0017987 name: cycs-apaf1-1 physical interaction comment: Interaction of Apaf-1 with Cytochrome c detected by co-immunoprecipitation. xref: IntAct:EBI-446561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN [Term] id: CCO:I0017988 name: cycs-apaf1-2 physical interaction comment: Interaction of Apaf-1 with Cytochrome c detected by co-immunoprecipitation. xref: IntAct:EBI-446565 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN [Term] id: CCO:I0017989 name: irak3-myd88-ex1 physical interaction comment: Interaction between IRAK-3 and MyD88 by co-immunoprecipitation xref: IntAct:EBI-447703 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:I0017990 name: irak1-myd88-ex1 physical interaction comment: Interaction between IRAK-1 and MyD88 by co-immunoprecipitation xref: IntAct:EBI-447720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0017991 name: irak2-myd88-ex1 physical interaction comment: Interaction between IRAK-2 and MyD88 by co-immunopreipitation xref: IntAct:EBI-447729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0017992 name: irak3-traf6-ex1 physical interaction comment: Interaction between IRAK-3 and Traf6 by co-immunoprecipitation xref: IntAct:EBI-447750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:I0017993 name: irak1-traf6-ex1 physical interaction comment: Interaction between IRAK-1 and Traf6 by co-immunopreipitation xref: IntAct:EBI-447766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:I0017994 name: irak2-traf6-ex1 physical interaction comment: Interaction between IRAK-2 and TRAF6 by co-immunopreipitation xref: IntAct:EBI-447775 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN [Term] id: CCO:I0017995 name: irak1-irak1-ex1 physical interaction comment: Homodimerization of IRAK-1 by co-immunoprecipitation xref: IntAct:EBI-447783 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:I0017996 name: irak2-irak2-ex1 physical interaction comment: Homodimerization of IRAK-2 by co-immunopreipitation xref: IntAct:EBI-447791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN [Term] id: CCO:I0017997 name: irak3-irak3-ex1 physical interaction comment: Homodimerization of IRAK-3 by co-immunoprecipitation xref: IntAct:EBI-447799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:I0017998 name: irak1-irak2-ex1 physical interaction comment: Heterodimerization of IRAK-1 and IRAK-2 by co-immunoprecipitation xref: IntAct:EBI-447809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:I0017999 name: irak1-irak3-ex1 physical interaction comment: Heterodimerization of IRAK-1 and IRAK-3 by co-immunoprecipitation xref: IntAct:EBI-447817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:I0018000 name: irak2-irak1-ex1 physical interaction comment: Heterodimerization of IRAK-2 and IRAK-1 by co-immunopreipitation xref: IntAct:EBI-447825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN [Term] id: CCO:I0018001 name: irak2-irak3-ex1 physical interaction comment: Heterodimerization of IRAK-2 and IRAK-3 by co-immunopreipitation xref: IntAct:EBI-447833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:I0018002 name: irak3-irak1-ex1 physical interaction comment: Heterodimerization of IRAK-3 by co-immunoprecipitation xref: IntAct:EBI-447841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:I0018003 name: irak3-irak2-ex1 physical interaction comment: Heterodimerization of IRAK-3 and IRAK-2 by co-immunoprecipitation xref: IntAct:EBI-447853 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:I0018004 name: map3k1-map2k4-3 physical interaction comment: Interaction between MAP3K1 and MAP2K4 demonstrated by GST pull-down xref: IntAct:EBI-447905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN [Term] id: CCO:I0018005 name: nek3-vav2-2 physical interaction xref: IntAct:EBI-476068 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028319 ! NEK3_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN [Term] id: CCO:I0018006 name: cdc42-was-8 physical interaction comment: fluorescence changes: WASP CRIB labelled with an iodoacetamide dye and endogenous cdc42 in HUVEC cells xref: IntAct:EBI-477278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0018007 name: trib3-atf4-4 physical interaction comment: Interaction detected by co-immunoprecipitation xref: IntAct:EBI-492526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0021435 ! ATF4_HUMAN [Term] id: CCO:I0018008 name: mkl2-mkl2-1 physical interaction comment: Interaction detected by coimmunprecipitation xref: IntAct:EBI-493173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:I0018009 name: mkl2-mkl1-1 physical interaction comment: Interaction detected by coimmunprecipitation xref: IntAct:EBI-493211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058143 ! MKL1_HUMAN relationship: has_participant CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:I0018010 name: pfkl-pfkm-4 physical interaction comment: Heterotetramer of liver and muscle phosphofructokinase - ML3 complex xref: IntAct:EBI-514834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0018011 name: pfkl-pfkm-5 physical interaction comment: Heterotetramer of liver and muscle phosphofructokinase - M2L2 complex xref: IntAct:EBI-514839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0018012 name: casp8-casp10-1 physical interaction comment: CoIP: bait= Caspase-10 preys = caspase-8, FLIP after TNF alpha stimulation xref: IntAct:EBI-515118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0058106 ! CASPA_HUMAN [Term] id: CCO:I0018013 name: bca3-prkaca-2 physical interaction comment: Interaction of PKA catalytic domain with BCA3 xref: IntAct:EBI-517047 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018543 ! KAPCA_HUMAN relationship: has_participant CCO:B0063233 ! BCA3_HUMAN [Term] id: CCO:I0018014 name: tnfrsf1a-tnfrsf1a-1 physical interaction comment: yeast 2-hybrid: bait = human TNFR1, prey = human TNFR1 xref: IntAct:EBI-517984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN [Term] id: CCO:I0018015 name: tnfrsf1a-tradd-1 physical interaction comment: yeast 2-hybrid: bait = human TNFR1, prey = human TRADD xref: IntAct:EBI-517998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0018016 name: tnfrsf6-fadd-12 physical interaction comment: GST pull-down: bait = cytoplasmic domain of FAS, prey = in vitro translated FADD xref: IntAct:EBI-518545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0018017 name: tnfrsf6-fadd-13 physical interaction comment: GST pull down : bait = cytoplasmic domain of FAS, prey = FADD xref: IntAct:EBI-518559 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0018018 name: tnfrsf6-tnfrsf6-2 physical interaction comment: Yeast2 Hybrid : bait = FAS, prey = FAS xref: IntAct:EBI-518780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN [Term] id: CCO:I0018019 name: tnsfrsf6-ripk1-1 physical interaction comment: Yeast 2 hybrid : bait = FAS, prey = RIP1 xref: IntAct:EBI-518794 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN [Term] id: CCO:I0018020 name: tac1-blys-4 direct interaction comment: The B-lymphocyte stimulator (BlyS) protein interacts with the tumor necrosis factor receptor superfamily member TAC1 xref: IntAct:EBI-519471 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0018021 name: casp2-cradd-1 physical interaction comment: In vivo Co-IP: bait= human caspase 2, prey = human RAIDD xref: IntAct:EBI-520368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN [Term] id: CCO:I0018022 name: lrdd-cradd-1 physical interaction comment: In vivo Co-IP: bait= PIDD, prey = death domain of RAIDD xref: IntAct:EBI-520437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0018023 name: casp2-cradd-3 physical interaction comment: In vivo Co-IP: bait= human caspase 2, prey = human RAIDD, prey= PIDD xref: IntAct:EBI-520456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0018024 name: casp2-cradd-5 physical interaction comment: In vivo Co-IP: bait= PIDD, prey = RAIDD, prey= caspase 2 xref: IntAct:EBI-520519 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0018025 name: cd27-siva physical interaction comment: The apoptosis regulatory protein Siva interacts with the C terminal region of the tumor necrosis factor receptor superfamily member 7 precursor protein (CD27) xref: IntAct:EBI-520752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054423 ! SIVA_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN [Term] id: CCO:I0018026 name: cd27-siva-1 physical interaction comment: The apoptosis regulatory protein Siva interacts with the tumor necrosis factor receptor superfamily member 7 precursor protein (CD27) xref: IntAct:EBI-520781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054423 ! SIVA_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN [Term] id: CCO:I0018027 name: birc7-casp9-2 physical interaction comment: pull-down: biotinylated peptide = caspase 9, prey = ML-IAP BIR domain xref: IntAct:EBI-521821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN [Term] id: CCO:I0018028 name: birc7-diablo-3 physical interaction comment: pull-down: biotinylated peptide = SMAC, prey = ML-IAP BIR domain xref: IntAct:EBI-521837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018029 name: birc7-prss25-1 physical interaction comment: pull-down: biotinylated peptide = htrA2, prey = ML-IAP BIR domain xref: IntAct:EBI-523439 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0063244 ! HTRA2_HUMAN [Term] id: CCO:I0018030 name: birc4-prss25-2 physical interaction comment: pull-down: biotinylated peptide = htrA2, prey = X-IAP BIR3 domain xref: IntAct:EBI-523462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0063244 ! HTRA2_HUMAN [Term] id: CCO:I0018031 name: birc4-diablo-4 physical interaction comment: pull-down: biotinylated peptide = SMAC, prey = X-IAP BIR3 domain xref: IntAct:EBI-523616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018032 name: birc4-casp9-3 physical interaction comment: pull-down: biotinylated peptide = caspase 9, prey = X-IAP BIR3 domain xref: IntAct:EBI-523664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0018033 name: atar-traf5-5 physical interaction comment: Coimmunoprecipitation reveals interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (ATAR) and the TNF receptor associated factor 5 protein (TRAF5) xref: IntAct:EBI-524017 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN [Term] id: CCO:I0018034 name: pellino-irak-irak4 physical interaction comment: Coimmunoprecipitation reveals interaction between the pellino protein homolog 1(Pellino) and Interleukin-1 receptor-associated kinase 1 (IRAK ) and the Interleukin-1 receptor-associated kinase-4 (IRAK4) proteins xref: IntAct:EBI-524742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN relationship: has_participant CCO:B0063242 ! PELI1_HUMAN [Term] id: CCO:I0018035 name: hip14-snap25-1 palmitoylation comment: in vitro palmitoylation of SNAP25 by HIP14 xref: IntAct:EBI-524783 is_a: CCO:Y0000023 ! palmitoylation reaction relationship: has_participant CCO:B0055598 ! SNP25_HUMAN relationship: has_participant CCO:B0057324 ! ZDH17_HUMAN [Term] id: CCO:I0018036 name: hip14-snap25-2 palmitoylation comment: in vitro palmitoylation of SNAP25 by HIP14 xref: IntAct:EBI-524831 is_a: CCO:Y0000023 ! palmitoylation reaction relationship: has_participant CCO:B0055598 ! SNP25_HUMAN relationship: has_participant CCO:B0057324 ! ZDH17_HUMAN [Term] id: CCO:I0018037 name: hip14-syt1-1 palmitoylation comment: in vitro palmitoylation of synaptotagmin I by HIP14 xref: IntAct:EBI-524929 is_a: CCO:Y0000023 ! palmitoylation reaction relationship: has_participant CCO:B0040103 ! SYT1_HUMAN relationship: has_participant CCO:B0057324 ! ZDH17_HUMAN [Term] id: CCO:I0018038 name: hip14-hd-2 palmitoylation comment: in vitro palmitoylation of Huntingtin by HIP14 xref: IntAct:EBI-524940 is_a: CCO:Y0000023 ! palmitoylation reaction relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0057324 ! ZDH17_HUMAN [Term] id: CCO:I0018039 name: il1r1-tirp physical interaction comment: Coimmunoprecipitation reveals interaction between the Interleukin-1 receptor, type I precursor (IL1R1) and the TRIF-related adapter molecule (TIRP) xref: IntAct:EBI-525923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN relationship: has_participant CCO:B0057293 ! TCAM2_HUMAN [Term] id: CCO:I0018040 name: il1racp-tirp-1 physical interaction comment: Coimmunoprecipitation reveals interaction between the Interleukin-1 receptor accessory protein precursor (IL1RAcp) and the TRIF-related adapter molecule (TIRP) xref: IntAct:EBI-525972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057293 ! TCAM2_HUMAN relationship: has_participant CCO:B0058853 ! IL1AP_HUMAN [Term] id: CCO:I0018041 name: traf6-tirp physical interaction comment: Coimmunoprecipitation reveals interaction between the TNF receptor associated factor 6 (TRAF6) and the TRIF-related adapter molecule (TIRP) xref: IntAct:EBI-526010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0057293 ! TCAM2_HUMAN [Term] id: CCO:I0018042 name: dicer1-eif2c2-3 physical interaction xref: IntAct:EBI-527694 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016049 ! I2C2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0018043 name: ikk_complex physical interaction comment: Anti bait coimmunoprecipitaion reveals the components of the cytokine responsive IkB complex xref: IntAct:EBI-528351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018044 name: cd27-traf2-1 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the tumor necrosis factor receptor superfamily member 7 precursor (CD27) and the TNF receptor associated factor 2 (TRAF2) xref: IntAct:EBI-528893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN [Term] id: CCO:I0018045 name: bcl9-ctnnb1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-533132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:I0018046 name: bcl9-ctnnb1-1 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-533202 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0006061 ! BCL9_HUMAN [Term] id: CCO:I0018047 name: araf-th1l-1 physical interaction comment: Y2H: bait = A-Raf ,prey = TH1-NELF-C/D xref: IntAct:EBI-536936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0018048 name: araf-c20orf14-1 physical interaction comment: Y2H: bait = A-Raf ,prey = TOM-U5 snRNP-associated 102 kDa protein xref: IntAct:EBI-536943 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0054708 ! PRP6_HUMAN [Term] id: CCO:I0018049 name: araf-htim44 physical interaction comment: Y2H: bait = A-Raf ,prey = TIMM44 xref: IntAct:EBI-536950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063251 ! TIM44_HUMAN [Term] id: CCO:I0018050 name: araf-cps1 physical interaction comment: Y2H: bait = A-Raf ,prey = CPS1-CPSM_HUMAN xref: IntAct:EBI-536957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:I0018051 name: araf-rras2 physical interaction comment: Y2H: bait = A-Raf ,prey = R-RAS xref: IntAct:EBI-536964 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN [Term] id: CCO:I0018052 name: araf-ass physical interaction comment: Y2H: bait = A-Raf ,prey = ASS-hA33M-ASSY_HUMAN xref: IntAct:EBI-536971 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063252 ! ASSY_HUMAN [Term] id: CCO:I0018053 name: araf-cops3 physical interaction comment: Y2H: bait = A-Raf ,prey = SGN3-COP9 complex subunit 3 xref: IntAct:EBI-536985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0018054 name: araf-nudt14 physical interaction comment: Y2H: bait = A-Raf ,prey = hA21-NU14_HUMAN-UGPPase xref: IntAct:EBI-536992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063253 ! NUD14_HUMAN [Term] id: CCO:I0018055 name: eif1a-eif5b-1 direct interaction comment: NMR chemical-shift uppon addition of eIF1A to eIF5B xref: IntAct:EBI-540289 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016435 ! IF1AY_HUMAN relationship: has_participant CCO:B0054581 ! IF2P_HUMAN [Term] id: CCO:I0018056 name: sin3a-sfpq-1 physical interaction xref: IntAct:EBI-591428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0018057 name: tak1-stat3-2 physical interaction comment: Identification of TAK1 as a STAT3-Interacting Protein by coimmunoprecipitation xref: IntAct:EBI-593614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:I0018058 name: tak1-stat3-3 physical interaction comment: Identification of TAK1 as a STAT3-Interacting Protein by coimmunoprecipitation xref: IntAct:EBI-593618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN [Term] id: CCO:I0018059 name: tak1-stat3-5 physical interaction comment: Identification of TAK1 as a STAT3-Interacting Protein by coimmunoprecipitation xref: IntAct:EBI-593694 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:I0018060 name: tak1-stat3-6 physical interaction comment: Identification of TAK1 as a STAT3-Interacting Protein by coimmunoprecipitation xref: IntAct:EBI-593725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:I0018061 name: gnai1-gpsm2-1 physical interaction xref: IntAct:EBI-618651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN [Term] id: CCO:I0018062 name: magoh-ddx48-2 physical interaction comment: pull down: bait=magoh, prey=eif4a3 xref: IntAct:EBI-619131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0063234 ! MGN_HUMAN [Term] id: CCO:I0018063 name: rbm8a-ddx48-2 physical interaction comment: pull down: bait=y14, prey=eif4a3 xref: IntAct:EBI-619136 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005223 ! RBM8A_HUMAN relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN [Term] id: CCO:I0018064 name: btk-gtf21-6 physical interaction comment: Interaction between BTK and GTF21 (BAP135) identified by coimmunoprecipitation xref: IntAct:EBI-627170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0018065 name: cir-sap30-1 physical interaction comment: Interaction between CIR and SAP30, detected by Y2H. xref: IntAct:EBI-632615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054637 ! SAP30_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0018066 name: dyrk1b-ranbp9-4 physical interaction comment: Interaction between DYRK1B and RANBP9 identified by coimmunoprecipitation xref: IntAct:EBI-636147 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN relationship: has_participant CCO:B0063004 ! RANB9_HUMAN [Term] id: CCO:I0018067 name: arid1a-smarca4-3 physical interaction comment: BAF complex subunits by CoIp xref: IntAct:EBI-638283 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0018068 name: smarca2-arid1a-1 physical interaction xref: IntAct:EBI-679727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0018069 name: smarca2-arid1b-1 physical interaction xref: IntAct:EBI-680087 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:I0018070 name: cdc42bpa-mlcb-1 phosphorylation comment: Phosphorylation of MLC2 by CDC42BPA demonstrated in vitro xref: IntAct:EBI-692039 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN relationship: has_participant CCO:B0061987 ! MRLC3_HUMAN [Term] id: CCO:I0018071 name: cdc42bpa-cdc42-2 direct interaction comment: Interation between CDC42BPA (MRCHalpha) and CDC42 xref: IntAct:EBI-692745 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0018072 name: cdc42bpa-cdc42-3 direct interaction comment: Interation between CDC42BPA (MRCKalpha) and CDC42 xref: IntAct:EBI-697149 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0018073 name: itga2b-itga2b-1 physical interaction comment: TOXCAT: Dimerization of alpha II b integrin TM region xref: IntAct:EBI-702720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:I0018074 name: gck-gckr-2 direct interaction comment: Interaction between GCK and GCKR1 identified by ELISA xref: IntAct:EBI-710154 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0018508 ! HXK4_HUMAN relationship: has_participant CCO:B0063245 ! GCKR_HUMAN [Term] id: CCO:I0018075 name: gck-pfkfb1-2 direct interaction comment: Interaction between GCK and PFKFB1 identified by ELISA xref: IntAct:EBI-710164 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0018508 ! HXK4_HUMAN relationship: has_participant CCO:B0033471 ! F261_HUMAN [Term] id: CCO:I0018076 name: hspb7-hspb1-1 physical interaction comment: Y2H: bait = HSP22 (HSPB8), prey = HSPB1 (HSP27) xref: IntAct:EBI-739417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0024107 ! HSPB8_HUMAN [Term] id: CCO:I0018077 name: hspb7-hspb1-2 physical interaction comment: Y2H: bait = HSP22 (HSPB8), prey = HSPB1 (HSP27) xref: IntAct:EBI-739424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0024107 ! HSPB8_HUMAN [Term] id: CCO:I0018078 name: pml-plzf-1 colocalization comment: Colocalization of PML and PLZF detected by confocal microscopy xref: IntAct:EBI-783084 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0018079 name: hrmt1l1-esr1-4 physical interaction comment: Interaction detected by FLAG tag. xref: IntAct:EBI-78705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0018080 name: app-chrna7-3 physical interaction comment: APP-alpha7 nicotinic acetylcholine receptor co-immunoprecipitation. xref: IntAct:EBI-79375 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0055310 ! ACHA7_HUMAN [Term] id: CCO:I0018081 name: bnip3alpha-bcl_xl-1 direct interaction comment: Interaction between human BNIP3alpha and BCL-XL detected by GST pulldown xref: IntAct:EBI-850652 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005175 ! BAD_HUMAN relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:I0018082 name: bnip3alpha-bcl_xl-2 direct interaction comment: Interaction between human BNIP3alpha deletion and BCL-XL detected by GST pulldown xref: IntAct:EBI-850691 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005175 ! BAD_HUMAN relationship: has_participant CCO:B0005714 ! BNI3L_HUMAN [Term] id: CCO:I0018083 name: flna-flnb-6 colocalization comment: Colocalization of Filamin A and Filamin B xref: IntAct:EBI-852131 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018084 name: atf6-hyst1481 physical interaction comment: Interaction detected by CoIp. xref: IntAct:EBI-852192 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018951 ! ATF6A_HUMAN relationship: has_participant CCO:B0056698 ! CR3L3_HUMAN [Term] id: CCO:I0018085 name: atf6-hyst1481-1 physical interaction comment: Interaction detected by CoIp. xref: IntAct:EBI-852240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018951 ! ATF6A_HUMAN relationship: has_participant CCO:B0056698 ! CR3L3_HUMAN [Term] id: CCO:I0018086 name: disc1-eif3s3 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and EIF3S3 protein xref: IntAct:EBI-928787 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0018087 name: disc1-itsn1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ITSN1 protein xref: IntAct:EBI-928807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0018088 name: disc1-eif3s3-4 physical interaction comment: Coimmunoprecipitation reveals interaction between the DISC1 protein and EIF3S3 protein xref: IntAct:EBI-930500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0018089 name: disc1-spectrin-2 physical interaction comment: Coimmunoprecipitation reveals interaction between the DISC1 protein and Beta-4-Spectrin protein xref: IntAct:EBI-930566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0058677 ! SPTN4_HUMAN [Term] id: CCO:I0018090 name: nerf2-aml1-2 physical interaction comment: Interaction between human NERF-2 and AML1 detected by coIP xref: IntAct:EBI-956999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033619 ! RUNX1_HUMAN relationship: has_participant CCO:B0056101 ! ELF2_HUMAN [Term] id: CCO:I0018091 name: mef-aml1-1 physical interaction comment: Interaction between human MEF and AML1 detected by coIP xref: IntAct:EBI-957026 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033619 ! RUNX1_HUMAN relationship: has_participant CCO:B0058430 ! ELF4_HUMAN [Term] id: CCO:I0018092 name: hash1-e2_2-1 physical interaction comment: Interaction between human HASH-1 and E2-2 detected by Y2H xref: IntAct:EBI-957051 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018093 name: calcrl-ramp1-1 colocalization comment: Colocalisation of CALCRL and RAMP1 xref: IntAct:EBI-962890 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0021417 ! CALRL_HUMAN relationship: has_participant CCO:B0054587 ! RAMP1_HUMAN [Term] id: CCO:I0018094 name: smad6-runx2-3 physical interaction xref: IntAct:EBI-976599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033622 ! RUNX2_HUMAN relationship: has_participant CCO:B0054488 ! SMAD6_HUMAN [Term] id: CCO:I0018095 name: ctnnb1-psen1 physical interaction xref: IntAct:EBI-988990 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0018096 name: jup-psen1-1 physical interaction xref: IntAct:EBI-989011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0018097 name: stk38l-mobk1b-1 physical interaction xref: IntAct:EBI-991487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015573 ! ST38L_HUMAN relationship: has_participant CCO:B0024568 ! MOL1B_HUMAN [Term] id: CCO:I0018098 name: rraga-rragc-1 physical interaction xref: IntAct:EBI-992943 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN [Term] id: CCO:I0018099 name: rraga-rragd-1 physical interaction xref: IntAct:EBI-992970 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0063034 ! RRAGD_HUMAN [Term] id: CCO:I0018100 name: c9orf26-il1rl1-1 direct interaction xref: IntAct:EBI-993803 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055691 ! ILRL1_HUMAN relationship: has_participant CCO:B0063254 ! IL33_HUMAN [Term] id: CCO:I0018101 name: dnmt3a-setdb1 direct interaction xref: IntAct:EBI-995207 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:I0018102 name: dnmt3a-setdb1-1 direct interaction xref: IntAct:EBI-995218 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:I0018103 name: dnmt3a-setdb1-2 direct interaction xref: IntAct:EBI-995292 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:I0018104 name: dnmt3a-setdb1-3 direct interaction xref: IntAct:EBI-995305 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:I0018105 name: casp2-pidd-3 colocalization comment: Interaction CASP2 and PIDD proteins xref: IntAct:EBI-995340 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0018106 name: raidd-pidd-4 colocalization comment: Interaction between RAIDD and PIDD proteins xref: IntAct:EBI-995346 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN [Term] id: CCO:I0018107 name: esr1-mll2 direct interaction xref: IntAct:EBI-996263 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:I0018108 name: nphs1-nck1 physical interaction comment: Pulldown analysis reveals interaction between Nephrin protein and NCK1 protein xref: IntAct:EBI-996887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0062983 ! NPHN_HUMAN [Term] id: CCO:I0018109 name: zfp36-dcp1a physical interaction xref: IntAct:EBI-1006378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:I0018110 name: zfp36-yjdc physical interaction xref: IntAct:EBI-1006636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005717 ! EDC3_HUMAN relationship: has_participant CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:I0018111 name: zfp36-rcd8-1 physical interaction xref: IntAct:EBI-1006825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005432 ! DCP1A_HUMAN relationship: has_participant CCO:B0005683 ! EDC4_HUMAN relationship: has_participant CCO:B0005717 ! EDC3_HUMAN relationship: has_participant CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:I0018112 name: taf11-taf13-3 direct interaction comment: Htafii18-htafii28 heterodimer crystal structure xref: IntAct:EBI-1027025 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0038317 ! TAF13_HUMAN relationship: has_participant CCO:B0056072 ! TAF11_HUMAN [Term] id: CCO:I0018113 name: taf11-taf13-4 direct interaction comment: Htafii18-htafii28 heterodimer crystal structure with bound pcmbs xref: IntAct:EBI-1027036 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0038317 ! TAF13_HUMAN relationship: has_participant CCO:B0056072 ! TAF11_HUMAN [Term] id: CCO:I0018114 name: ngfb-ntrk1-1 direct interaction comment: Ngf in complex with domain 5 of the trka receptor xref: IntAct:EBI-1028266 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0054892 ! NTRK1_HUMAN [Term] id: CCO:I0018115 name: birc4-casp3-1 physical interaction comment: Crystal structure of the complex of xiap-bir2 and caspase 3 xref: IntAct:EBI-1030919 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055351 ! CASP3_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0018116 name: csnk2a1-csnk2b-1 direct interaction comment: Crystal structure of human protein kinase ck2 holoenzyme xref: IntAct:EBI-1032078 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005428 ! CSK21_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:I0018117 name: fnta-fntb-2 direct interaction comment: Crystal structure of human protein farnesyltransferase complexed with farnesyl diphosphate and the peptidomimetic inhibitor l-739,750 xref: IntAct:EBI-1032208 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:I0018118 name: il6-il6r-1 physical interaction comment: Crystal structure of the hexameric human il-6-il-6 alpha receptor-gp130 complex xref: IntAct:EBI-1036752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025184 ! IL6RB_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054933 ! IL6RA_HUMAN [Term] id: CCO:I0018119 name: bckdha-bckdhb-5 direct interaction comment: Crosstalk between cofactor binding and the phosphorylation loop conformation in the bckd machine xref: IntAct:EBI-1039060 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018120 name: bckdha-bckdhb-6 direct interaction comment: Crosstalk between cofactor binding and the phosphorylation loop conformation in the bckd machine xref: IntAct:EBI-1039071 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018121 name: bckdha-bckdhb-7 direct interaction comment: Crosstalk between cofactor binding and the phosphorylation loop conformation in the bckd machine xref: IntAct:EBI-1039082 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018122 name: bckdha-bckdhb-8 direct interaction comment: Crosstalk between cofactor binding and the phosphorylation loop conformation in the bckd machine xref: IntAct:EBI-1039093 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018123 name: map3k13-mapk13-1 physical interaction comment: Homodimerization of MAP3K13 identified by coimmunoprecipitation xref: IntAct:EBI-1168499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018761 ! M3K13_HUMAN [Term] id: CCO:I0018124 name: map3k13-mapk13-2 physical interaction comment: Homodimerization of MAP3K13 identified by coimmunoprecipitation xref: IntAct:EBI-1168511 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018761 ! M3K13_HUMAN [Term] id: CCO:I0018125 name: hif1a-os9 physical interaction comment: OS-9 interacted with HIF-1 alpha in a yeast two hybrid assay xref: IntAct:EBI-1174334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0018126 name: rela-aatf physical interaction comment: Che-1 coimmunoprecipitates with p65 xref: IntAct:EBI-1180975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005446 ! AATF_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018127 name: rela-aatf-1 physical interaction comment: Che-1 coimmunoprecipitates with p65 xref: IntAct:EBI-1180984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005446 ! AATF_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018128 name: pak2-limk1-1 direct interaction comment: Interaction between PAK2 and LIMK1 demonstrated by nmr xref: IntAct:EBI-1182678 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN relationship: has_participant CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:I0018129 name: pak2-raf1-1 direct interaction comment: Interaction between PAK2 and RAF1 demonstrated by nmr xref: IntAct:EBI-1182700 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0024022 ! PAK2_HUMAN [Term] id: CCO:I0018130 name: nmi-stat3-1 physical interaction comment: Interaction between human Nmi and Stat3 detected by pulldown xref: IntAct:EBI-1186457 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN [Term] id: CCO:I0018131 name: nmi-stat6-1 physical interaction comment: Interaction between human Nmi and Stat6 detected by pulldown xref: IntAct:EBI-1186474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0029685 ! STAT6_HUMAN [Term] id: CCO:I0018132 name: magec1-gtf2f1 physical interaction comment: In a yeast two-hybrid assay MAGE-C1/CT7 interacts with GTF2F1 xref: IntAct:EBI-1188495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005354 ! T2FA_HUMAN relationship: has_participant CCO:B0022509 ! MAGC1_HUMAN [Term] id: CCO:I0018133 name: app-apbb3 physical interaction comment: FE65L2-APP Interaction xref: IntAct:EBI-286447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063259 ! APBB3_HUMAN [Term] id: CCO:I0018134 name: apbb3-aplp2 physical interaction comment: FE65L2-APLP2 interaction xref: IntAct:EBI-286465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005374 ! APLP2_HUMAN relationship: has_participant CCO:B0063259 ! APBB3_HUMAN [Term] id: CCO:I0018135 name: dach-madh4-1 physical interaction xref: IntAct:EBI-347276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN [Term] id: CCO:I0018136 name: app-hadh2-2 physical interaction comment: amyloid beta-HADH2(ERAB) interaction demonstrated by ELISA xref: IntAct:EBI-371735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063213 ! HCD2_HUMAN [Term] id: CCO:I0018137 name: prkcq-txnl2-3 physical interaction comment: Interaction between PKCtheat and TXNL2 confirmed by GST pull-down xref: IntAct:EBI-374811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0062932 ! GLRX3_HUMAN [Term] id: CCO:I0018138 name: prkcq-txnl2-4 colocalization comment: Interaction between PKCtheta and TXNL2 confirmed by colocalisation xref: IntAct:EBI-374816 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0062932 ! GLRX3_HUMAN [Term] id: CCO:I0018139 name: abi1-spta1-2 physical interaction xref: IntAct:EBI-375636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0063212 ! SPTA1_HUMAN [Term] id: CCO:I0018140 name: gtf2a1-tbp-1 physical interaction comment: TBP binds TFIIA, TFIIB and HMG-1 xref: IntAct:EBI-389553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0055488 ! TF2AA_HUMAN [Term] id: CCO:I0018141 name: gtf2b-tbp-1 physical interaction comment: TBP binds TFIIA, TFIIB and HMG-1 xref: IntAct:EBI-389581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0022444 ! TF2B_HUMAN [Term] id: CCO:I0018142 name: hmgb1-tbp-1 physical interaction comment: TBP binds TFIIA, TFIIB and HMG-1. xref: IntAct:EBI-389586 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN [Term] id: CCO:I0018143 name: abi1-nckap1-3 physical interaction xref: IntAct:EBI-389864 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0050612 ! NCKP1_HUMAN [Term] id: CCO:I0018144 name: pparbp-crsp2-1 physical interaction comment: Interaction detected by fractionation off phosphocellulose at P1.0 followed by MudPIT. xref: IntAct:EBI-395135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN [Term] id: CCO:I0018145 name: rnf11-amsh-1 physical interaction comment: Identification of binding partners of RNF11 by Y2H xref: IntAct:EBI-396708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005424 ! EP15_HUMAN relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0062996 ! RNF11_HUMAN [Term] id: CCO:I0018146 name: irak4-peli2-4 phosphorylation comment: Phosphorylation of PELI2 by IRAK4 xref: IntAct:EBI-448443 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN relationship: has_participant CCO:B0063261 ! PELI2_HUMAN [Term] id: CCO:I0018147 name: irak1-peli2-3 physical interaction comment: Phosphorylation of PELI2 by IRAK1 xref: IntAct:EBI-448451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0063261 ! PELI2_HUMAN [Term] id: CCO:I0018148 name: arf1-pscd2-3 direct interaction comment: Crystal structure of human Arf1 - human ARNO sec7 domain complexed with Brefeldin A xref: IntAct:EBI-449105 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0015288 ! ARF1_HUMAN relationship: has_participant CCO:B0058410 ! CYH2_HUMAN [Term] id: CCO:I0018149 name: arf1-pscd2-4 direct interaction comment: Crystal structure of human Arf1 - human ARNO sec7 domain (mutated in E156K) complexed with Brefeldin A xref: IntAct:EBI-449117 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0015288 ! ARF1_HUMAN relationship: has_participant CCO:B0058410 ! CYH2_HUMAN [Term] id: CCO:I0018150 name: eif4gi-ncbp2 physical interaction comment: eIF4G is required for the pioneer round of translation in mammalian cells xref: IntAct:EBI-464727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN relationship: has_participant CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:I0018151 name: eif4gi-ncbp1 physical interaction comment: eIF4G is required for the pioneer round of translation in mammalian cells xref: IntAct:EBI-464885 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN relationship: has_participant CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:I0018152 name: hd-git1-6 colocalization comment: Co-localization of endogenous huntingtin with endogenous GIT-1 in SH-SY5Y cells xref: IntAct:EBI-472972 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018153 name: soh1-hd physical interaction xref: IntAct:EBI-473337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0018154 name: crmp1-hd physical interaction xref: IntAct:EBI-473348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0018155 name: fez1-hd physical interaction xref: IntAct:EBI-473359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018156 name: git1-hd physical interaction xref: IntAct:EBI-473370 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018157 name: ikbkap-hd physical interaction xref: IntAct:EBI-473414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018158 name: g22p1-hd physical interaction xref: IntAct:EBI-473425 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0018159 name: pfn2-hd physical interaction xref: IntAct:EBI-473436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0018160 name: pias4-hd physical interaction xref: IntAct:EBI-473447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018161 name: kiaa1377-hd physical interaction xref: IntAct:EBI-473458 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018162 name: kiaa1377-git1 physical interaction xref: IntAct:EBI-473480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0018163 name: kiaa1377-hbo1 physical interaction xref: IntAct:EBI-473524 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0018164 name: gadd45g-kiaa1377 physical interaction xref: IntAct:EBI-473557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN [Term] id: CCO:I0018165 name: smt3h2-pias4 physical interaction comment: pull-down: PIASy and SUMO3 xref: IntAct:EBI-473568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0018166 name: kiaa1377-htatip physical interaction xref: IntAct:EBI-473590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005403 ! K1377_HUMAN [Term] id: CCO:I0018167 name: gadd45g-htatip physical interaction xref: IntAct:EBI-473601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN [Term] id: CCO:I0018168 name: gadd45g-utp14a physical interaction xref: IntAct:EBI-473634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0018169 name: soh1-gadd45g physical interaction xref: IntAct:EBI-473667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0018170 name: rac1-pak1-4 direct interaction comment: FRET in living cells: GFP-Rac1 and PAK1 PDB domain labelled with Alexa-546 dye xref: IntAct:EBI-476889 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:I0018171 name: rac1-ncf2-3 direct interaction comment: Crystal structure: Human Rac1 Q61L GTP and P67 phox TPR domains xref: IntAct:EBI-489678 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0063026 ! NCF2_HUMAN [Term] id: CCO:I0018172 name: dhx9-hrmt1l2-1 physical interaction xref: IntAct:EBI-491501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:I0018173 name: hrmt1l2-dhx9-1 physical interaction xref: IntAct:EBI-491520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0005804 ! DHX9_HUMAN [Term] id: CCO:I0018174 name: mast2-pclkc-4 colocalization comment: Colocalization of MAST2 and PC-LKC demonstrated by co-immunofluorescence xref: IntAct:EBI-493858 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0056876 ! MAST2_HUMAN relationship: has_participant CCO:B0058577 ! PCD24_HUMAN [Term] id: CCO:I0018175 name: prkcq-txnl2-5 physical interaction comment: Interaction between PKCtheat and TXNL2 confirmed by GST pull-down xref: IntAct:EBI-516638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0062932 ! GLRX3_HUMAN [Term] id: CCO:I0018176 name: insr-irs1-1 physical interaction comment: Interaction between insulin receptor substrate 1 and the insulin receptor demonstrated by Y2H. xref: IntAct:EBI-517654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:I0018177 name: insr-irs1-2 physical interaction comment: Interaction between insulin receptor substrate 1 and the insulin receptor demonstrated by Y2H. xref: IntAct:EBI-517667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:I0018178 name: gzma-gzma-1 covalent binding comment: Crystal structure of the apoptosis-inducing human granzyme A dimer. xref: IntAct:EBI-519830 is_a: CCO:Y0000005 ! covalent binding relationship: has_participant CCO:B0055002 ! GRAA_HUMAN [Term] id: CCO:I0018179 name: birc4-diablo-1 physical interaction comment: Co-IP: bait = X-IAP, prey = SMAC xref: IntAct:EBI-521811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018180 name: hvem-traf1 physical interaction comment: GST-pulldown demnonstrates interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (HVEM) and TNF receptor associated factor 1 (TRAF1) xref: IntAct:EBI-523424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN [Term] id: CCO:I0018181 name: hvem-traf3 physical interaction comment: GST-pulldown demnonstrates interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (HVEM) and TNF receptor associated factor 3 (TRAF3) xref: IntAct:EBI-523454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN [Term] id: CCO:I0018182 name: hvem-traf5 physical interaction comment: GST-pulldown demnonstrates interaction between the tumor necrosis factor receptor superfamily member 14 precursor protein (HVEM) and TNF receptor associated factor 5 (TRAF5) xref: IntAct:EBI-523474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN [Term] id: CCO:I0018183 name: cgi-cdh_3 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the Plasminogen activator inhibitor 1 RNA-binding protein (CGI-55) N-terminal region and the chromodomain helicase-DNA-binding protein 3 (CDH-3) protein xref: IntAct:EBI-523644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:I0018184 name: cgi-cdh_3-2 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the Plasminogen activator inhibitor 1 RNA-binding protein (CGI-55) C-terminal region and the chromodomain helicase-DNA-binding protein 3 (CDH-3) protein xref: IntAct:EBI-523653 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:I0018185 name: birc7-diablo-2 physical interaction comment: Co-IP: bait = ML-IAP, prey = SMAC xref: IntAct:EBI-523685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018186 name: cdh_3-cgi-1 physical interaction comment: GST pulldown reveals in vitro interaction between the C terminal region of the chromodomain helicase-DNA-binding protein 3 and the plasminogen activator inhibitor 1 RNA-binding protein (CGI-55) xref: IntAct:EBI-523774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:I0018187 name: birc7-casp9-1 physical interaction comment: Co-IP: bait = ML-IAP, prey = P35 caspase 9 xref: IntAct:EBI-523798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN [Term] id: CCO:I0018188 name: birc7-diablo-6 physical interaction comment: Co-IP: bait = SMAC, prey = ML-IAP xref: IntAct:EBI-523809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018189 name: ang-actn2-3 physical interaction comment: CoIP: bait= human angiogenin, prey= human alpha-actinin-2 xref: IntAct:EBI-525368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN [Term] id: CCO:I0018190 name: msn-nherf-2 physical interaction comment: Interaction between the FERM domain of Moesin and the C-terminus of EBP50 detected by affinity chromatography xref: IntAct:EBI-528793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018220 ! MOES_HUMAN relationship: has_participant CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:I0018191 name: msn-nherf-3 physical interaction comment: Interaction between FERM domain of Moesin and a EBP50 C-terminus peptide detected by affinity chromatography xref: IntAct:EBI-528806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018220 ! MOES_HUMAN relationship: has_participant CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:I0018192 name: ppie-cyp33-1 physical interaction comment: Interaction of Cyp33 and MLL, as detected by Y2H. xref: IntAct:EBI-591814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005486 ! HRX_HUMAN relationship: has_participant CCO:B0059255 ! PPIE_HUMAN [Term] id: CCO:I0018193 name: ccr1-plp2-3 colocalization comment: Colocalization of CCR1 and PLP2 detected by confocal microscopy xref: IntAct:EBI-608384 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055740 ! PLP2_HUMAN [Term] id: CCO:I0018194 name: epor-plcg21-3 physical interaction comment: Interaction between human EpoR and PLCgamma2 demonstrated by MAPPIT xref: IntAct:EBI-617672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055061 ! PLCG2_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0018195 name: btk-sh3bp5-4 physical interaction comment: Interaction between BTK and SH3BP5 (SAB) identified by GST pulldown xref: IntAct:EBI-625056 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0018196 name: btk-gtf21-5 phosphorylation comment: Interaction between BTK and GTF21 (BAP135) identified by kinase assay xref: IntAct:EBI-625174 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0018197 name: rac1-arfip2-2 physical interaction comment: Interaction of Rac1 and POR1 detected by yeast two hybrid. xref: IntAct:EBI-687876 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018198 name: rnf11-ep15-1 physical interaction comment: Identification of binding partners of RNF11 by Y2H xref: IntAct:EBI-696052 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005424 ! EP15_HUMAN relationship: has_participant CCO:B0062996 ! RNF11_HUMAN [Term] id: CCO:I0018199 name: atx2-pabp physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the ataxin-2 protein and PABP protein xref: IntAct:EBI-698679 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0018200 name: hsp1-hsp4-8 physical interaction comment: Co-sedimentation of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0018201 name: hsp1-hsp4-10 physical interaction comment: Co-sedimentation of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0018202 name: hsp1-hsp4-15 physical interaction comment: Co-sedimentation of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0018203 name: wrn-g22p1-1 physical interaction comment: Affinity chromatography: bait= WRN c-terminus , prey = Ku86, ku70 xref: IntAct:EBI-707448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0018204 name: pfkfb1-1 direct interaction comment: Homodimerzation of PFKFB1 identified by x-ray crystallography xref: IntAct:EBI-709820 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0033471 ! F261_HUMAN [Term] id: CCO:I0018205 name: bcl2l1-bcap31 physical interaction comment: Interaction of BCL-XL with p28Bap31 identified by co-immunoprecipitation xref: IntAct:EBI-78034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005676 ! BAP31_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0018206 name: casp8-bcap31 physical interaction comment: Interaction of Caspase-8 with p28Bap31 identified by co-immunoprecipitation xref: IntAct:EBI-78059 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005676 ! BAP31_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0018207 name: edf1-pparg-3 physical interaction comment: MBF-1 interacts with PPARgamma in a mammalian two-hybrid system. xref: IntAct:EBI-781612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0018208 name: mapk8ip1-app-2 physical interaction comment: mapk8ip1-app in vivo xref: IntAct:EBI-78437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0059280 ! JIP1_HUMAN [Term] id: CCO:I0018209 name: ephb1-grb10-2 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-80319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0014969 ! EPHB1_HUMAN relationship: has_participant CCO:B0055897 ! GRB10_HUMAN [Term] id: CCO:I0018210 name: ephb1-grb2-2 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-80325 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0014969 ! EPHB1_HUMAN [Term] id: CCO:I0018211 name: ncoa3-crebbp-ncoa2-1 physical interaction xref: IntAct:EBI-81304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0062892 ! RO52_HUMAN [Term] id: CCO:I0018212 name: ncoa3-ikbkb physical interaction xref: IntAct:EBI-81323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0018213 name: ncoa1-ncoa2-crebbp physical interaction xref: IntAct:EBI-81326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0062892 ! RO52_HUMAN [Term] id: CCO:I0018214 name: polg-polg2-3 physical interaction comment: Stoichiometry of POLG and POLG2 identified by isothermal titration calorimetry xref: IntAct:EBI-852738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:I0018215 name: polg-polg2-4 physical interaction comment: Stoichiometry of POLG and POLG2 identified by isothermal titration calorimetry xref: IntAct:EBI-852755 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:I0018216 name: sp1-sp1-1 physical interaction comment: Homodimerisation of human Sp1 detected by GST pulldown xref: IntAct:EBI-862683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005485 ! SP1_HUMAN [Term] id: CCO:I0018217 name: z39ig-c3 physical interaction comment: Interaction detected by cytometric determination. xref: IntAct:EBI-903153 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036109 ! CO3_HUMAN relationship: has_participant CCO:B0049025 ! O95973_HUMAN [Term] id: CCO:I0018218 name: hbxap-smarca5-2 colocalization xref: IntAct:EBI-926828 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0058398 ! RSF1_HUMAN [Term] id: CCO:I0018219 name: ighg1-fcg2b-1 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by calorimetry xref: IntAct:EBI-941649 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0018220 name: ighg1-fcg2b-2 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by calorimetry xref: IntAct:EBI-941671 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0018221 name: ighg1-fcg2b-3 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by calorimetry xref: IntAct:EBI-942059 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0018222 name: ighg1-fcg2b-4 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by calorimetry xref: IntAct:EBI-942073 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0018223 name: ighg1-fcg2b-5 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by calorimetry xref: IntAct:EBI-942091 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0018224 name: ighg1-fcg2b-6 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by calorimetry xref: IntAct:EBI-942108 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0018225 name: ighg1-fcg2b-7 direct interaction comment: Interaction between IgG-Fc and sFcgamma RIIb determined by calorimetry xref: IntAct:EBI-942125 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0034317 ! IGHG1_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0018226 name: hash1-e2_2-3 physical interaction comment: Interaction between human HASH-1 and E2-2 detected by mammalian two-hybrid xref: IntAct:EBI-957122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018227 name: e2_2-hash1-1 physical interaction comment: Interaction between human E2-2 and HASH-1 detected by mammalian two-hybrid xref: IntAct:EBI-957134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018228 name: hash1-e47-1 physical interaction comment: Interaction between human HASH-1 and E47 detected by mammalian two-hybrid xref: IntAct:EBI-957142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018229 name: e47-hash1-1 physical interaction comment: Interaction between human E47 and HASH-1 detected by mammalian two-hybrid xref: IntAct:EBI-957152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018230 name: e2_2-e2_2-1 physical interaction comment: Homodimerisation of human E2-2 detected by mammalian two-hybrid xref: IntAct:EBI-957162 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005715 ! ITF2_HUMAN [Term] id: CCO:I0018231 name: gch1-aha1-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between GCH1 protein and Aha1protein xref: IntAct:EBI-958317 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0063014 ! AHSA1_HUMAN [Term] id: CCO:I0018232 name: gch1-cb1_1p1-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between GCH1 protein and CB1-1P1 protein xref: IntAct:EBI-958322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0063262 ! CNRP1_HUMAN [Term] id: CCO:I0018233 name: gch1-hsc70-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between GCH1 protein and HSc70 protein xref: IntAct:EBI-958327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0050722 ! GCH1_HUMAN [Term] id: CCO:I0018234 name: gch1-rab26-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between GCH1 protein and Rab26 protein xref: IntAct:EBI-958332 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0059236 ! RAB26_HUMAN [Term] id: CCO:I0018235 name: gch1-rlf-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between GCH1 protein and RFL protein xref: IntAct:EBI-958337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0055877 ! RLF_HUMAN [Term] id: CCO:I0018236 name: gch1-gch1 physical interaction comment: Directed yeast 2 hybrid analysis reveals dimer formation GCH1 protein xref: IntAct:EBI-958368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN [Term] id: CCO:I0018237 name: gch1-grfp physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between GCH1 protein and GFRP protein xref: IntAct:EBI-958378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0063263 ! GFRP_HUMAN [Term] id: CCO:I0018238 name: smad6-runx2 physical interaction xref: IntAct:EBI-976397 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033622 ! RUNX2_HUMAN relationship: has_participant CCO:B0054488 ! SMAD6_HUMAN [Term] id: CCO:I0018239 name: smurf-runx2 physical interaction xref: IntAct:EBI-976494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033622 ! RUNX2_HUMAN relationship: has_participant CCO:B0058805 ! SMUF1_HUMAN [Term] id: CCO:I0018240 name: smad6-runx2-1 physical interaction xref: IntAct:EBI-976535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033622 ! RUNX2_HUMAN relationship: has_participant CCO:B0054488 ! SMAD6_HUMAN [Term] id: CCO:I0018241 name: ikbkb-nfkbia-5 physical interaction comment: Association of I-kappa B alpha, I-kappa kinase beta and I-kappa kinase gamma xref: IntAct:EBI-986145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018242 name: mmp14-adi1-1 physical interaction xref: IntAct:EBI-992803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032391 ! MTND_HUMAN relationship: has_participant CCO:B0055446 ! MMP14_HUMAN [Term] id: CCO:I0018243 name: cbx5-mbd1-1 physical interaction xref: IntAct:EBI-994652 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0018244 name: mll2-rbq3 physical interaction xref: IntAct:EBI-996116 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0005660 ! RBBP5_HUMAN relationship: has_participant CCO:B0006000 ! WDR5B_HUMAN relationship: has_participant CCO:B0050359 ! MLL2_HUMAN [Term] id: CCO:I0018245 name: gstp1-jnk1 physical interaction comment: Coimmunoprecipitation assay reveals interaction between GSTP1 and JNK1 proteins xref: IntAct:EBI-996190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005577 ! M3K5_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN [Term] id: CCO:I0018246 name: gstp1-mapk13 physical interaction comment: Coimmunoprecipitation assay reveals interaction between GSTP1 and MAPK13 proteins xref: IntAct:EBI-996222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN [Term] id: CCO:I0018247 name: gstp1-traf2 physical interaction comment: Coimmunoprecipitation assay reveals interaction between GSTP1 and TRAF2 proteins xref: IntAct:EBI-996244 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN [Term] id: CCO:I0018248 name: mt2a-cxorf40a-2 physical interaction xref: IntAct:EBI-996641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063264 ! CX04A_HUMAN [Term] id: CCO:I0018249 name: erbb4-erbb2 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between ErbB4 protein and ErbB2 protein xref: IntAct:EBI-1008282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:I0018250 name: ncbp1-ncbp2-4 direct interaction comment: Cap binding complex xref: IntAct:EBI-1034907 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN relationship: has_participant CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:I0018251 name: ncbp1-ncbp2-5 direct interaction comment: Cap binding complex m7gpppg free xref: IntAct:EBI-1034918 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN relationship: has_participant CCO:B0063016 ! NCBP2_HUMAN [Term] id: CCO:I0018252 name: bckdha-bckdhb-2 direct interaction comment: Roles of his291-alpha and his146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1036952 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018253 name: bckdha-bckdhb-3 direct interaction comment: Roles of his291-alpha and his146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1036963 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018254 name: bckdha-bckdhb-4 direct interaction comment: Roles of his291-alpha and his146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1036974 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018255 name: senp2-sumo1-1 direct interaction comment: Structure of human senp2 in complex with sumo-1 xref: IntAct:EBI-1039804 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN relationship: has_participant CCO:B0036139 ! SENP2_HUMAN [Term] id: CCO:I0018256 name: hspa1a-hspbp1-1 direct interaction comment: Crystal structure of the hspbp1 core domain complexed with the fragment of hsp70 atpase domain xref: IntAct:EBI-1041692 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005199 ! HPBP1_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN [Term] id: CCO:I0018257 name: hba1-hbb-18 direct interaction comment: T-to-thigh quaternary transitions in human hemoglobin: betav1m deoxy low-salt (10 test sets) xref: IntAct:EBI-1042156 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018258 name: abl2-rin1-1 physical interaction comment: Interaction between Abl2 and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005385 ! RIN1_HUMAN relationship: has_participant CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:I0018259 name: abl2-rin1-3 physical interaction comment: Interaction between Abl2 and Rin1 identified by coimmunoprecipitation xref: IntAct:EBI-1102781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005385 ! RIN1_HUMAN relationship: has_participant CCO:B0005685 ! ABL2_HUMAN [Term] id: CCO:I0018260 name: fnbp1-tnks-1 physical interaction xref: IntAct:EBI-1111242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005386 ! FNBP1_HUMAN relationship: has_participant CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:I0018261 name: fnbp1-tnks-4 colocalization xref: IntAct:EBI-1111372 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005386 ! FNBP1_HUMAN relationship: has_participant CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:I0018262 name: dj_1-dj_1 physical interaction xref: IntAct:EBI-1164376 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005443 ! PARK7_HUMAN [Term] id: CCO:I0018263 name: dj_1-uba2 physical interaction xref: IntAct:EBI-1164395 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005443 ! PARK7_HUMAN relationship: has_participant CCO:B0063247 ! SAE2_HUMAN [Term] id: CCO:I0018264 name: tap1-pd1a3-1 direct interaction xref: IntAct:EBI-1168183 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005889 ! TAP1_HUMAN relationship: has_participant CCO:B0042031 ! PDIA3_HUMAN [Term] id: CCO:I0018265 name: hif1a-os9-1 direct interaction comment: GST-HIF-1 alpha pulls down OS-9 xref: IntAct:EBI-1174473 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0018266 name: os9-egln3-1 physical interaction comment: GST-HIF-1alpha pulls down PHD3 xref: IntAct:EBI-1175422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0029358 ! EGLN3_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0018267 name: hif1a-os9-5 direct interaction comment: GST-HIF-1 alpha pulls down OS-9 xref: IntAct:EBI-1175516 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0063250 ! OS9_HUMAN [Term] id: CCO:I0018268 name: qsk-ywhaz-1 physical interaction comment: Binding partners of QSK identified by mass spectrometry xref: IntAct:EBI-1181492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:I0018269 name: cdr2-morf4l2-1 direct interaction comment: PCD17 and MRG X colocalize in T98G cells xref: IntAct:EBI-1181585 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0063018 ! CDR2_HUMAN [Term] id: CCO:I0018270 name: mark1-ywhaz-1 physical interaction comment: Binding partners of MARK1 identified by mass spectrometry xref: IntAct:EBI-1181753 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0037393 ! MARK1_HUMAN [Term] id: CCO:I0018271 name: mark2-ywhaz-2 physical interaction comment: Binding partners of MARK2 identified by mass spectrometry xref: IntAct:EBI-1181766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:I0018272 name: mark3-ywhaz-1 physical interaction comment: Binding partners of MARK3identified by mass spectrometry xref: IntAct:EBI-1181773 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005229 ! MARK3_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN [Term] id: CCO:I0018273 name: mark4-ywhaz-3 physical interaction comment: Binding partners of MARK4 identified by mass spectrometry xref: IntAct:EBI-1181800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN [Term] id: CCO:I0018274 name: qsk-ywhaz-5 direct interaction comment: Interaction between 14-3-3Z and QSK identified by pulldown xref: IntAct:EBI-1181916 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0063019 ! QSK_HUMAN [Term] id: CCO:I0018275 name: 4et-eif4e physical interaction comment: A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E xref: IntAct:EBI-301045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006012 ! 4ET_HUMAN relationship: has_participant CCO:B0016186 ! IF4E_HUMAN [Term] id: CCO:I0018276 name: ywhah-prkci-1 physical interaction comment: Comprehensive proteomic analysis of human par protein complexes reveals an interconnected protein network xref: IntAct:EBI-306968 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0018277 name: prkci-mark4-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005344 ! MARK4_HUMAN [Term] id: CCO:I0018278 name: prkci-par5-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0018279 name: ywhah-mark4-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-307276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0018280 name: hck-elmo1-2 physical interaction comment: Interaction between HCK and ELMO1 detected by CoIP xref: IntAct:EBI-346452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0018281 name: dach-sin3a-1 physical interaction xref: IntAct:EBI-347230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN [Term] id: CCO:I0018282 name: dach-ncor1-1 physical interaction xref: IntAct:EBI-347258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:I0018283 name: pnma1-mark4-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-349690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0005877 ! PNMA1_HUMAN [Term] id: CCO:I0018284 name: pnma1-prcki-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-349771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005877 ! PNMA1_HUMAN [Term] id: CCO:I0018285 name: clcn3-slc9a3r1-1 physical interaction comment: Interaction of CLCN3 and SLC9A3R1 detected by GST pull down. xref: IntAct:EBI-349807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025071 ! NHERF_HUMAN relationship: has_participant CCO:B0037912 ! CLCN3_HUMAN [Term] id: CCO:I0018286 name: cftr-pist-1 physical interaction comment: Interaction of CFTR and GOPC (PIST) detected by GST pull down. xref: IntAct:EBI-349890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0063033 ! GOPC_HUMAN [Term] id: CCO:I0018287 name: cftr-slc9a3r1-1 physical interaction comment: Interaction of CTFR and EBP50 (SLC9A3R1) detected by GST pull down. xref: IntAct:EBI-349895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:I0018288 name: ywhaz-prkci-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354745 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0018289 name: mark4-ywhah-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354797 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN [Term] id: CCO:I0018290 name: ywhaz-mark4-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0018291 name: mark4-ywhaz-1 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-354807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0018292 name: prkci-cdc42-2 physical interaction comment: Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network xref: IntAct:EBI-360114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0018293 name: cdc42-prkci-1 physical interaction comment: CoIP: bait = human cdc42, prey = PKC ioata xref: IntAct:EBI-360119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:I0018294 name: ncoa3-ikbkb-1 physical interaction xref: IntAct:EBI-370890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0018295 name: c20orf20-epc1-3 physical interaction comment: The complex Copurifies from a K-SP NPR HPLC column. xref: IntAct:EBI-399293 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN [Term] id: CCO:I0018296 name: rac1-elmo1-1 physical interaction comment: Dock1 and Elmo1are pulled-down by nucleotide-free Rac1-GST xref: IntAct:EBI-446898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0018297 name: rac1-dock-1 physical interaction comment: Purified Dock1 and Elmo1are pulled-down by nucleotide-free Rac1-GST xref: IntAct:EBI-446978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0018298 name: ahsa1-hspca-1 physical interaction comment: two-hybrid, bait = human Aha1, prey = human hsp90 xref: IntAct:EBI-448609 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0063014 ! AHSA1_HUMAN [Term] id: CCO:I0018299 name: zcsl2-gnefr-2 physical interaction comment: Interaction detected by cotransformation. xref: IntAct:EBI-465439 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026978 ! DPH3_HUMAN relationship: has_participant CCO:B0059123 ! SRGEF_HUMAN [Term] id: CCO:I0018300 name: emd-bclaf1-1 physical interaction comment: Two hybid detection of emerin interaction with btf. xref: IntAct:EBI-489904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058962 ! BCLF1_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:I0018301 name: emd-bclaf1-2 direct interaction comment: Scintillation proximity assay of emerin interacting with btf. xref: IntAct:EBI-490049 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0058962 ! BCLF1_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:I0018302 name: dhx9-rela-2 physical interaction comment: Interaction of RELA with Flag-tagged DHX9 demonstrated by in vivo co-immunoprecipitation. xref: IntAct:EBI-491452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018303 name: srf-mkl2-1 physical interaction comment: Interaction detected by coimmunprecipitation xref: IntAct:EBI-493111 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:I0018304 name: srf-mkl1-1 physical interaction comment: Interaction detected by coimmunprecipitation xref: IntAct:EBI-493135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0058143 ! MKL1_HUMAN [Term] id: CCO:I0018305 name: hd-crebbp-1 physical interaction comment: GST-pull down : bait = huntingtin poly(Q) region ; prey = CBP (CREB binding Protein) xref: IntAct:EBI-493147 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018306 name: hd-crebbp-2 physical interaction comment: GST-pull down : bait = huntingtin poly(Q) region ; prey = CBP (CREB binding Protein) xref: IntAct:EBI-493190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018307 name: pfkl-pfkm-1 physical interaction comment: Heterotetramer of liver and muscle phosphofructokinase - ML3 complex xref: IntAct:EBI-514807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0018308 name: pfkl-pfkm-2 physical interaction comment: Heterotetramer of liver and muscle phosphofructokinase - M2L2 complex xref: IntAct:EBI-514812 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0018309 name: pfkl-pfkm-3 physical interaction comment: Heterotetramer of liver and muscle phosphofructokinase - M3L complex xref: IntAct:EBI-514817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0018310 name: fadd-mbd4-3 physical interaction comment: The FADD protein interacts with the Methyl CpG binding protein 4 xref: IntAct:EBI-518332 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0063002 ! MBD4_HUMAN [Term] id: CCO:I0018311 name: erbb4-dlg4-5 physical interaction comment: Interaction detected by coimmunoprecipitation xref: IntAct:EBI-525174 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:I0018312 name: rnase3l-dgcr8-2 physical interaction xref: IntAct:EBI-528472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006026 ! RNC_HUMAN relationship: has_participant CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:I0018313 name: rnase3l-dgcr8-3 physical interaction xref: IntAct:EBI-528493 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006026 ! RNC_HUMAN relationship: has_participant CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:I0018314 name: tnf_r1-tradd-1 physical interaction comment: Coimmunoprecipitation reveals components of the tumor necrosis factor receptor signalling complex xref: IntAct:EBI-531249 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0018315 name: stk25-golga2-2 physical interaction comment: Interaction between YSK1 and GM130 identified by Y2H xref: IntAct:EBI-618324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN relationship: has_participant CCO:B0022748 ! STK25_HUMAN [Term] id: CCO:I0018316 name: gpsm2-gpsm2-1 physical interaction xref: IntAct:EBI-618859 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN [Term] id: CCO:I0018317 name: ddx48-thoc4-1 direct interaction comment: pull down: bait=eif4a3, preys=tap, aly/ref, hnrnp a1, hnrnp c1 xref: IntAct:EBI-619182 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005774 ! ROA1_HUMAN relationship: has_participant CCO:B0017403 ! THOC4_HUMAN relationship: has_participant CCO:B0018046 ! NXF1_HUMAN relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN [Term] id: CCO:I0018318 name: btk-sh3bp5-2 physical interaction comment: Interaction between BTK and SH3BP5 (SAB) identified by GST pulldown xref: IntAct:EBI-624876 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0018319 name: btk-sh3bp5-3 physical interaction comment: Interaction between BTK and SH3BP5 (SAB) identified by GST pulldown xref: IntAct:EBI-625046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0018320 name: zn655-vav1-2 physical interaction comment: Interaction between ZN655 (VIK) and VAV1 identified by Y2H xref: IntAct:EBI-625582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005578 ! ZN655_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:I0018321 name: cir-rbpsuh-2 colocalization comment: Interaction of CIR and CBF-1, as detected by coimmunofluoresence. xref: IntAct:EBI-632584 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0055767 ! SUH_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0018322 name: hdac2-cir-1 physical interaction comment: Interaction of HDAC2 and CIR detected by yeast two hybrid. xref: IntAct:EBI-633387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0018323 name: dyrk1b-dcohm-2 direct interaction comment: Interaction between DYRK1B and DCOHM identified by in vitro coimmunoprecipitation xref: IntAct:EBI-634844 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0058656 ! PHS2_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0018324 name: dyrk1b-dcohm-3 physical interaction comment: Interaction between DYRK1B, TCF1 (HNF1alpha) and DCOHM identified by GST pulldown xref: IntAct:EBI-636031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0058656 ! PHS2_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0018325 name: dyrk1b-tcf1-1 direct interaction comment: Interaction between DYRK1B and TCF1 (HNF1alpha) identified by GST pulldown xref: IntAct:EBI-636062 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0018326 name: arid1b-smarca2-3 physical interaction xref: IntAct:EBI-683457 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:I0018327 name: arid1a-smarca4-4 physical interaction xref: IntAct:EBI-684252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0018328 name: arid1a--smarca2-2 physical interaction xref: IntAct:EBI-684512 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN [Term] id: CCO:I0018329 name: arid1b-smarca4-5 physical interaction xref: IntAct:EBI-684569 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:I0018330 name: arfip2-arfip2 physical interaction comment: Interaction of N-terminus POR1 fragment interacted with C-terminus POR1 fragment, as detected by yeast two hybrid. xref: IntAct:EBI-695953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018331 name: rac1-arfip2-3 physical interaction comment: Interaction between Rac1 and POR1 as detected by yeast two hybrid. xref: IntAct:EBI-696088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018332 name: lcp1-atx2 physical interaction comment: Coimmunoprecipitaion reveals interaction between L-Plastin and ataxin-2 xref: IntAct:EBI-698049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:I0018333 name: tcp1-atx2-1 physical interaction comment: Coimmunoprecipitaion reveals interaction between T-Plastin and ataxin-2 xref: IntAct:EBI-698061 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0019585 ! PLST_HUMAN [Term] id: CCO:I0018334 name: rpa2-rpa3-1 physical interaction comment: Y2H: bait = RPA32, prey= RPA14 xref: IntAct:EBI-707149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005501 ! RFA3_HUMAN [Term] id: CCO:I0018335 name: xrcc5-g22p1-1 phosphorylation comment: In vivo Co-IP: bait = ku86, prey= ku70, WRN xref: IntAct:EBI-707473 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0018336 name: wrn-g22p1-3 phosphorylation comment: In vivo Co-IP: bait = WRN, prey= ku86, ku70 xref: IntAct:EBI-707478 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0018337 name: wrn-fen1-3 direct interaction comment: Affinity chromatography: bait = FEN-1, prey = WRN xref: IntAct:EBI-707691 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0018338 name: atxn7-taf10 physical interaction comment: Colocalisation of reveals interaction between Ataxin 7 protein and TAF10 protein xref: IntAct:EBI-708572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0018339 name: adam9-pacsin3-1 physical interaction xref: IntAct:EBI-77935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0018340 name: adam9-sh3gl2-1 physical interaction xref: IntAct:EBI-77953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018341 name: plzf-pml-1 physical interaction comment: Interaction between PLZF and PML detected by co-immunoprecipitation xref: IntAct:EBI-779721 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0018342 name: edf1-nr1h3-3 physical interaction comment: MBF-1 interacts with LXR-alpha in mammalian cells and stimulates their ligand-dependent transcriptional activity. xref: IntAct:EBI-781599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054582 ! EDF1_HUMAN relationship: has_participant CCO:B0055878 ! NR1H3_HUMAN [Term] id: CCO:I0018343 name: tbp-edf1-1 physical interaction comment: MBF-1 interacts with in vitro translated TBP, as detected by pull down. xref: IntAct:EBI-781665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0018344 name: pim1-bmx-4 physical interaction comment: Interaction between PIM1 and BMX identified by coimmunoprecipitation xref: IntAct:EBI-783010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005923 ! BMX_HUMAN relationship: has_participant CCO:B0022781 ! PIM1_HUMAN [Term] id: CCO:I0018345 name: pim1-bmx-7 physical interaction comment: Interaction between PIM1 and BMX identified by coimmunoprecipitation xref: IntAct:EBI-783054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005923 ! BMX_HUMAN relationship: has_participant CCO:B0022781 ! PIM1_HUMAN [Term] id: CCO:I0018346 name: pml-plzf-2 colocalization comment: Colocalization of PML and PLZF detected by confocal microscopy xref: IntAct:EBI-783097 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:I0018347 name: abca1-utrn physical interaction comment: Affinity chromatograhy assay reveals ABCA1 interacting proteins. xref: IntAct:EBI-784135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0063265 ! SNTA1_HUMAN relationship: has_participant CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:I0018348 name: abca1-sntb1-1 physical interaction comment: Peptide array assay reveals ABCA1 interacts with beta-1-syntrophin. xref: IntAct:EBI-784230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:I0018349 name: abca1-snta1 physical interaction comment: Peptide array assay reveals ABCA1 interacts with alpha-1-syntrophin. xref: IntAct:EBI-784242 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0063265 ! SNTA1_HUMAN [Term] id: CCO:I0018350 name: abca1-dgl3 physical interaction comment: Peptide array assay reveals ABCA1 interacts with DGL3. xref: IntAct:EBI-784253 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023306 ! DLG3_HUMAN relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN [Term] id: CCO:I0018351 name: esr1-hrmt1l1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-78498 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN [Term] id: CCO:I0018352 name: acnn1-prkcabp-1 physical interaction xref: IntAct:EBI-79148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0063267 ! ACCN1_HUMAN [Term] id: CCO:I0018353 name: accn1-prkcabp-1 physical interaction xref: IntAct:EBI-79220 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0063267 ! ACCN1_HUMAN [Term] id: CCO:I0018354 name: dnmt3b-ubl1-1 physical interaction xref: IntAct:EBI-80165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN [Term] id: CCO:I0018355 name: erbb4-dlg4-3 physical interaction comment: Interaction detected by coimmunoprecipitation xref: IntAct:EBI-80771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:I0018356 name: ncoa3-ikbkg-1 physical interaction xref: IntAct:EBI-81312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0018357 name: pabp-paip1 2 physical interaction comment: Paip1 interacts with poly(A) binding protein through two independent binding motifs xref: IntAct:EBI-81552 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN [Term] id: CCO:I0018358 name: paip1-pabp 2 physical interaction comment: Paip1 interacts with poly(A) binding protein through two independent binding motifs xref: IntAct:EBI-81556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN [Term] id: CCO:I0018359 name: abca1-arhgef12 physical interaction comment: Peptide array assay reveals ABCA1 interacts with ARHGEF12 xref: IntAct:EBI-821465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0059006 ! ARHGC_HUMAN [Term] id: CCO:I0018360 name: abca1-mpdz physical interaction comment: Peptide array assay reveals ABCA1 interacts with MPDZ protein xref: IntAct:EBI-821477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0063268 ! MPDZ_HUMAN [Term] id: CCO:I0018361 name: abca1-dig2 physical interaction comment: Peptide array assay reveals ABCA1 interacts with DIG2 protein xref: IntAct:EBI-821488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023320 ! DLG2_HUMAN relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN [Term] id: CCO:I0018362 name: abca1-lin7b physical interaction comment: Peptide array assay reveals ABCA1 interacts with LIN7B protein xref: IntAct:EBI-821538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0063269 ! LIN7B_HUMAN [Term] id: CCO:I0018363 name: nip3-nip3-1 physical interaction comment: Homodimerisation of human Nip3 detected by coIP xref: IntAct:EBI-850225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN [Term] id: CCO:I0018364 name: pole3-pole4-1 physical interaction comment: Interaction between POLE3 and POLE4 identified by coimmunoprecipitation xref: IntAct:EBI-867043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:I0018365 name: pole3-pole4-2 physical interaction comment: Interaction between POLE3 and POLE4 identified by coimmunoprecipitation xref: IntAct:EBI-867075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:I0018366 name: disc1-atf4-1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ATF4 protein xref: IntAct:EBI-929089 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0021435 ! ATF4_HUMAN [Term] id: CCO:I0018367 name: disc1-eif3s3-2 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and EIF3S3 protein xref: IntAct:EBI-929105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0018368 name: disc1-rassf7-1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and RASSF7 protein xref: IntAct:EBI-929117 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0055716 ! RASF7_HUMAN [Term] id: CCO:I0018369 name: disc1-itsn1-1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ITSN1 protein xref: IntAct:EBI-929121 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0018370 name: disc1-spectrin-1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and Beta-4-Spectrin protein xref: IntAct:EBI-929149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0058677 ! SPTN4_HUMAN [Term] id: CCO:I0018371 name: atxn1-ubqln4-1 colocalization comment: Colocalisation analysis reveals interaction between Ataxin-1 protein and Ubiquilin-4 protein xref: IntAct:EBI-930989 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018372 name: nerf2-aml1-1 direct interaction comment: Interaction between human NERF-2 and AML1 detected by pulldown xref: IntAct:EBI-956982 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0033619 ! RUNX1_HUMAN relationship: has_participant CCO:B0056101 ! ELF2_HUMAN [Term] id: CCO:I0018373 name: ifnar2-gnb2l1-1 physical interaction comment: Interaction of IFNAR2 and GNB2L1 identified by Y2H xref: IntAct:EBI-958438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0055406 ! INAR2_HUMAN [Term] id: CCO:I0018374 name: rnf5-pxn-2 physical interaction xref: IntAct:EBI-963485 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0018375 name: rnf5-pxn-4 physical interaction xref: IntAct:EBI-963509 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0018376 name: birc2-traf2-1 physical interaction comment: Interaction between BIRC2 (cIAP1) and TRAF2 identified by coimmunoprecipitation xref: IntAct:EBI-976995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN [Term] id: CCO:I0018377 name: birc2-diablo-1 physical interaction comment: Interaction between BIRC2 (cIAP1) and DIABLO (SMAC) identified by coimmunoprecipitation xref: IntAct:EBI-977009 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018378 name: birc4-diablo-6 physical interaction comment: Interaction between BIRC4 (XIAP) and DIABLO (SMAC) identified by coimmunoprecipitation xref: IntAct:EBI-977023 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018379 name: birc2-traf2-4 physical interaction comment: Interaction between BIRC2 (cIAP1) and TRAF2 identified by coimmunoprecipitation xref: IntAct:EBI-977108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN [Term] id: CCO:I0018380 name: birc2-diablo-2 physical interaction comment: Interaction between BIRC2 (cIAP1) and DIABLO (SMAC) identified by coimmunoprecipitation xref: IntAct:EBI-977186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018381 name: il15-il15ra physical interaction comment: sIL-15Ralpha-IL-2 xref: IntAct:EBI-980314 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055332 ! IL15_HUMAN relationship: has_participant CCO:B0055891 ! I15RA_HUMAN [Term] id: CCO:I0018382 name: il15-il15ra-1 physical interaction comment: sIL-15Ralpha-sushi-IL-2 CHO xref: IntAct:EBI-983582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055332 ! IL15_HUMAN relationship: has_participant CCO:B0055891 ! I15RA_HUMAN [Term] id: CCO:I0018383 name: il15-il15ra-2 physical interaction comment: sIL-15Ralpha-sushi E. coli xref: IntAct:EBI-983600 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055332 ! IL15_HUMAN relationship: has_participant CCO:B0055891 ! I15RA_HUMAN [Term] id: CCO:I0018384 name: foxp2-nfatc2 direct interaction xref: IntAct:EBI-983671 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0015717 ! FOXP2_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:I0018385 name: ikbkb-4 physical interaction comment: Homodimerisation of I-kappa kinase beta xref: IntAct:EBI-986069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0018386 name: ikbkb-5 physical interaction comment: Heterodimerisation of I-kappa kinase beta and I-kappa kinase alpha xref: IntAct:EBI-986086 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018387 name: ikbkb-nfkbia-4 physical interaction comment: Association of I-kappa kinase beta and I-kappa kinase gamma xref: IntAct:EBI-986104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0018388 name: arhgap24-flna-5 colocalization comment: Interaction between ARHGAP24 and FLNA identified by colocalization xref: IntAct:EBI-989206 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN [Term] id: CCO:I0018389 name: mmp14-adi1-3 physical interaction xref: IntAct:EBI-992868 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032391 ! MTND_HUMAN relationship: has_participant CCO:B0055446 ! MMP14_HUMAN [Term] id: CCO:I0018390 name: mbd1-cbx5-2 physical interaction xref: IntAct:EBI-994697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0018391 name: daz1-pum2-1 physical interaction xref: IntAct:EBI-997993 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:I0018392 name: daz1-pum2-3 physical interaction xref: IntAct:EBI-998105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:I0018393 name: daz1-dzip1-1 physical interaction xref: IntAct:EBI-998144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0063270 ! DZIP1_HUMAN [Term] id: CCO:I0018394 name: daz1-dzip3-1 physical interaction xref: IntAct:EBI-998149 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0063271 ! DZIP3_HUMAN [Term] id: CCO:I0018395 name: daz1-dazl-1 physical interaction xref: IntAct:EBI-998172 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0058111 ! DAZL_HUMAN [Term] id: CCO:I0018396 name: daz1-qk3-1 physical interaction xref: IntAct:EBI-998194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0063272 ! Q8WY44_HUMAN [Term] id: CCO:I0018397 name: erbb4-dlg4 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between ErbB4 protein and DLG4 protein xref: IntAct:EBI-998522 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:I0018398 name: erbb4-nmdar1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between ErbB4 protein and NMDAR1 protein xref: IntAct:EBI-998599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0055744 ! NMDZ1_HUMAN [Term] id: CCO:I0018399 name: grp94-pek-1 physical interaction comment: Interaction between human GRP94 and PEK detected by coIP xref: IntAct:EBI-1017489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006015 ! E2AK3_HUMAN relationship: has_participant CCO:B0055025 ! ENPL_HUMAN [Term] id: CCO:I0018400 name: hif1a-hif1an-1 direct interaction comment: Factor inhibiting hif-1 alpha in complex with hif-1 alpha fragment peptide xref: IntAct:EBI-1035055 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0058941 ! HIF1N_HUMAN [Term] id: CCO:I0018401 name: hif1a-hif1an-2 direct interaction comment: Factor inhibiting hif-1 alpha in complex with hif-1 alpha fragment peptide xref: IntAct:EBI-1035066 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0058941 ! HIF1N_HUMAN [Term] id: CCO:I0018402 name: hif1a-hif1an-3 direct interaction comment: Factor inhibiting hif-1 alpha in complex with hif-1 alpha fragment peptide xref: IntAct:EBI-1035077 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0058941 ! HIF1N_HUMAN [Term] id: CCO:I0018403 name: cga-fshb-2 physical interaction comment: Crystal structure of human follicle stimulating hormone complexed with its receptor xref: IntAct:EBI-1041469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005506 ! FSHR_HUMAN relationship: has_participant CCO:B0006263 ! GLHA_HUMAN relationship: has_participant CCO:B0054839 ! FSHB_HUMAN [Term] id: CCO:I0018404 name: il6st-ptpn1 physical interaction comment: pull down of SHP-2 by gp130 peptide pY2 xref: IntAct:EBI-1163557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025184 ! IL6RB_HUMAN relationship: has_participant CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:I0018405 name: tap1-pd1a3 direct interaction xref: IntAct:EBI-1168132 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005889 ! TAP1_HUMAN relationship: has_participant CCO:B0042031 ! PDIA3_HUMAN [Term] id: CCO:I0018406 name: morf4l2-cdr2-1 physical interaction comment: PDC17 interacts with MRG X in a yeast two-hybrid assay xref: IntAct:EBI-1181518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0063018 ! CDR2_HUMAN [Term] id: CCO:I0018407 name: morf4l2-cdr2-2 physical interaction comment: PDC17 interacts with MRG X in a yeast two-hybrid assay xref: IntAct:EBI-1181536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0063018 ! CDR2_HUMAN [Term] id: CCO:I0018408 name: nmi-sox10-1 physical interaction comment: Interaction between human Nmi and Sox10 detected by coIP xref: IntAct:EBI-1185717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0055547 ! SOX10_HUMAN [Term] id: CCO:I0018409 name: sox10-nmi-2 physical interaction comment: Interaction between human Sox10 and Nmi detected by coIP xref: IntAct:EBI-1185730 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0055547 ! SOX10_HUMAN [Term] id: CCO:I0018410 name: zbtb16-q8iub0-1 physical interaction comment: PLZF interacts with CCS-3 in a yeast two-hybrid assay xref: IntAct:EBI-1189449 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN relationship: has_participant CCO:B0063237 ! Q8IUB0_HUMAN [Term] id: CCO:I0018411 name: all1-all1 direct interaction xref: IntAct:EBI-1202065 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:I0018412 name: mapk11-atf2 phosphorylation comment: Human p38 isolated from BJ cells phosphorylates ATF2 in vitro xref: IntAct:EBI-1206337 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005892 ! MK11_HUMAN relationship: has_participant CCO:B0018367 ! ATF2_HUMAN [Term] id: CCO:I0018413 name: ghr-ncoa6-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0063273 ! GHR_HUMAN [Term] id: CCO:I0018414 name: ncoa6-thra-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0054978 ! THA_HUMAN [Term] id: CCO:I0018415 name: ncoa6-thrb-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286339 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0054979 ! THB_HUMAN [Term] id: CCO:I0018416 name: ncoa6-rxra-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286345 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0024886 ! RXRA_HUMAN [Term] id: CCO:I0018417 name: ncoa6-esr1-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:I0018418 name: ncoa6-vdr-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0054992 ! VDR_HUMAN [Term] id: CCO:I0018419 name: ncoa6-thra-2 physical interaction comment: Regions of hNCOA6 important for interactions determined by Y2H. xref: IntAct:EBI-286377 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0054978 ! THA_HUMAN [Term] id: CCO:I0018420 name: ncoa6-thrb-2 physical interaction comment: Regions of hNCOA6 important for interactions determined by Y2H. xref: IntAct:EBI-286380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0054979 ! THB_HUMAN [Term] id: CCO:I0018421 name: ncoa6-rxra-2 physical interaction comment: Regions of hNCOA6 important for interactions determined by Y2H. xref: IntAct:EBI-286394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0024886 ! RXRA_HUMAN [Term] id: CCO:I0018422 name: ncoa6-esr1-2 physical interaction comment: Regions of hNCOA6 important for interactions determined by Y2H. xref: IntAct:EBI-286402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:I0018423 name: ncoa6-ghr-2 physical interaction comment: Regions of hNCOA6 important for interactions determined by Y2H. xref: IntAct:EBI-286407 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0063273 ! GHR_HUMAN [Term] id: CCO:I0018424 name: ncoa6-vdr-2 physical interaction comment: Regions of hNCOA6 important for interactions determined by Y2H. xref: IntAct:EBI-286412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0054992 ! VDR_HUMAN [Term] id: CCO:I0018425 name: ncoa6-ncoa6-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-286474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN [Term] id: CCO:I0018426 name: polr2a-ercc6-1 physical interaction comment: size fractionation of the XAB2, RNA Pol II, CSB complex. xref: IntAct:EBI-295336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0041548 ! SYF1_HUMAN relationship: has_participant CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:I0018427 name: hck-sos1-1 physical interaction comment: Interaction between HCK and SOS1 detected by GST pull down xref: IntAct:EBI-346591 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0018428 name: hck-ddef1-1 physical interaction comment: Interaction between HCK and DDEF1 detected by GST pull down xref: IntAct:EBI-346643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005894 ! HCK_HUMAN relationship: has_participant CCO:B0059225 ! DDEF1_HUMAN [Term] id: CCO:I0018429 name: hck-hnrpk-1 physical interaction comment: Interaction between HCK and HNRPK detected by GST pull down xref: IntAct:EBI-346649 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0018430 name: hck-evl-1 physical interaction comment: Interaction between HCK and EVL detected by GST pull down xref: IntAct:EBI-346687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005894 ! HCK_HUMAN relationship: has_participant CCO:B0059153 ! EVL_HUMAN [Term] id: CCO:I0018431 name: hck-sh3bp1-1 physical interaction comment: Interaction between HCK and SH3BP1 detected by GST pull down xref: IntAct:EBI-346878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005894 ! HCK_HUMAN relationship: has_participant CCO:B0059338 ! 3BP1_HUMAN [Term] id: CCO:I0018432 name: hck-tsg101-1 physical interaction comment: Interaction between HCK and TSG101 detected by GST pull down xref: IntAct:EBI-346902 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0018433 name: hck-pik3r2-1 physical interaction comment: Interaction between HCK and PIK3R2 detected by GST pull down xref: IntAct:EBI-346942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005894 ! HCK_HUMAN relationship: has_participant CCO:B0026602 ! P85B_HUMAN [Term] id: CCO:I0018434 name: hck-lcp2-1 physical interaction comment: Interaction between HCK and LCP2 detected by GST pull down xref: IntAct:EBI-346957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005894 ! HCK_HUMAN relationship: has_participant CCO:B0055872 ! LCP2_HUMAN [Term] id: CCO:I0018435 name: hck-pik3r1-1 physical interaction comment: Interaction between HCK and PIK3R1 detected by GST pull down xref: IntAct:EBI-346963 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005894 ! HCK_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0018436 name: hck-elmo1-4 physical interaction comment: Interaction between HCK and ELMO1 detected by GST pull down xref: IntAct:EBI-347010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0005894 ! HCK_HUMAN [Term] id: CCO:I0018437 name: pbx2-ikbkap physical interaction xref: IntAct:EBI-348652 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:I0018438 name: pbx2-gcn5l1 physical interaction xref: IntAct:EBI-348655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005895 ! PBX2_HUMAN relationship: has_participant CCO:B0006194 ! BL1S1_HUMAN [Term] id: CCO:I0018439 name: pbx2-smyd3 physical interaction xref: IntAct:EBI-348658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005895 ! PBX2_HUMAN relationship: has_participant CCO:B0063274 ! SMYD3_HUMAN [Term] id: CCO:I0018440 name: pbx2-zdhhc7 physical interaction xref: IntAct:EBI-348661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005895 ! PBX2_HUMAN relationship: has_participant CCO:B0063275 ! ZDHC7_HUMAN [Term] id: CCO:I0018441 name: pbx2-kiaa0052 physical interaction xref: IntAct:EBI-348667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005346 ! SK2L2_HUMAN relationship: has_participant CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:I0018442 name: pbx2-nup62 physical interaction xref: IntAct:EBI-348670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005895 ! PBX2_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN [Term] id: CCO:I0018443 name: pbx2-irsp53 physical interaction xref: IntAct:EBI-348676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005895 ! PBX2_HUMAN relationship: has_participant CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:I0018444 name: pbx2-rpl4 physical interaction xref: IntAct:EBI-348682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005861 ! RL4_HUMAN relationship: has_participant CCO:B0005895 ! PBX2_HUMAN [Term] id: CCO:I0018445 name: hsrma1-ubch9 physical interaction xref: IntAct:EBI-348694 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043430 ! RNF5_HUMAN relationship: has_participant CCO:B0043535 ! UB2E3_HUMAN [Term] id: CCO:I0018446 name: hsrma1-ube2d3 physical interaction xref: IntAct:EBI-348700 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019461 ! UB2D3_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0018447 name: stk19-sp3 physical interaction xref: IntAct:EBI-348715 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005896 ! STK19_HUMAN relationship: has_participant CCO:B0055710 ! SP3_HUMAN [Term] id: CCO:I0018448 name: rdbp-nelfb physical interaction xref: IntAct:EBI-348727 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055102 ! NELFE_HUMAN relationship: has_participant CCO:B0058011 ! NELFB_HUMAN [Term] id: CCO:I0018449 name: rdbp-ncor1 physical interaction xref: IntAct:EBI-348730 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054626 ! NCOR1_HUMAN relationship: has_participant CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:I0018450 name: lsm2-znf408 physical interaction xref: IntAct:EBI-348748 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0062972 ! LSM2_HUMAN [Term] id: CCO:I0018451 name: clic1-lsm1 physical interaction xref: IntAct:EBI-348754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006005 ! LSM1_HUMAN relationship: has_participant CCO:B0054309 ! CLIC1_HUMAN [Term] id: CCO:I0018452 name: bat5-gprc5c physical interaction xref: IntAct:EBI-348778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005571 ! BAT5_HUMAN relationship: has_participant CCO:B0058864 ! GPC5C_HUMAN [Term] id: CCO:I0018453 name: bat5-q9ukj0 physical interaction xref: IntAct:EBI-348781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005571 ! BAT5_HUMAN relationship: has_participant CCO:B0015778 ! PILRB_HUMAN [Term] id: CCO:I0018454 name: bat5-safb physical interaction xref: IntAct:EBI-348787 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005571 ! BAT5_HUMAN relationship: has_participant CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:I0018455 name: csnk2b-lyn physical interaction xref: IntAct:EBI-348799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:I0018456 name: csnk2b-csnk2a1 physical interaction xref: IntAct:EBI-348802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005428 ! CSK21_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:I0018457 name: csnk2b-csnk2b physical interaction xref: IntAct:EBI-348805 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:I0018458 name: csnk2b-znhit1 physical interaction xref: IntAct:EBI-348811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005362 ! ZNHI1_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:I0018459 name: csnk2b-mbd4 physical interaction xref: IntAct:EBI-348814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN relationship: has_participant CCO:B0063002 ! MBD4_HUMAN [Term] id: CCO:I0018460 name: csnk2b-znf44 physical interaction xref: IntAct:EBI-348817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN relationship: has_participant CCO:B0055040 ! ZNF44_HUMAN [Term] id: CCO:I0018461 name: g18_1b-fgfr3 physical interaction xref: IntAct:EBI-348820 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0059363 ! GPSM3_HUMAN [Term] id: CCO:I0018462 name: bat2-eif3s6 physical interaction xref: IntAct:EBI-348835 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005898 ! BAT2_HUMAN relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:I0018463 name: bat2-ddx20 physical interaction xref: IntAct:EBI-348838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005898 ! BAT2_HUMAN relationship: has_participant CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:I0018464 name: bat2-fga physical interaction xref: IntAct:EBI-348841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005898 ! BAT2_HUMAN relationship: has_participant CCO:B0054865 ! FIBA_HUMAN [Term] id: CCO:I0018465 name: bat2-hrmt1l1 physical interaction xref: IntAct:EBI-348847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:I0018466 name: bat2-gpr2 physical interaction xref: IntAct:EBI-348859 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005898 ! BAT2_HUMAN relationship: has_participant CCO:B0018440 ! CCR10_HUMAN [Term] id: CCO:I0018467 name: bat2-tg737 physical interaction xref: IntAct:EBI-348868 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005898 ! BAT2_HUMAN relationship: has_participant CCO:B0055873 ! IFT88_HUMAN [Term] id: CCO:I0018468 name: bat2-grb2 physical interaction xref: IntAct:EBI-348886 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:I0018469 name: lst1-q8wuq7 physical interaction xref: IntAct:EBI-348895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054322 ! LST1_HUMAN relationship: has_participant CCO:B0063276 ! CS029_HUMAN [Term] id: CCO:I0018470 name: bat1-hcc1 physical interaction xref: IntAct:EBI-348907 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005899 ! UAP56_HUMAN relationship: has_participant CCO:B0055658 ! HCC1_HUMAN [Term] id: CCO:I0018471 name: bat1-zhx1 physical interaction xref: IntAct:EBI-348916 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005899 ! UAP56_HUMAN [Term] id: CCO:I0018472 name: bat1-piasx physical interaction xref: IntAct:EBI-348922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005321 ! PIAS2_HUMAN relationship: has_participant CCO:B0005899 ! UAP56_HUMAN [Term] id: CCO:I0018473 name: bat1-tdg physical interaction xref: IntAct:EBI-348925 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005899 ! UAP56_HUMAN relationship: has_participant CCO:B0055930 ! TDG_HUMAN [Term] id: CCO:I0018474 name: tesk1-spry4-2 physical interaction comment: Interaction of TSEK1 and SPRY4 confirmed by coimmunoprecipitation xref: IntAct:EBI-354890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058614 ! SPY4_HUMAN relationship: has_participant CCO:B0063231 ! TESK1_HUMAN [Term] id: CCO:I0018475 name: tesk1-spry4-3 physical interaction comment: Interaction of TESK1 and SPRY4 confirmed by coimmunoprecipitation xref: IntAct:EBI-354896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058614 ! SPY4_HUMAN relationship: has_participant CCO:B0063231 ! TESK1_HUMAN [Term] id: CCO:I0018476 name: c20orf20-epc1-1 physical interaction comment: Interaction detected by Anti-FLAG coimmunoprecipitation. xref: IntAct:EBI-399119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN [Term] id: CCO:I0018477 name: eea1-rab22a-1 physical interaction comment: Interaction of Rab22a with EEA1 detected by Y2H. xref: IntAct:EBI-399468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005237 ! RB22A_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0018478 name: eea1-rab22a-2 physical interaction comment: Interaction by Rab22a and EEA1 detected by Y2H. xref: IntAct:EBI-399473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005237 ! RB22A_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0018479 name: ixl-usp49-1 physical interaction comment: Interaction detected by anti FLAG CoIP. xref: IntAct:EBI-399734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN [Term] id: CCO:I0018480 name: ixl-usp49-2 physical interaction comment: Interaction detected by anti FLAG CoIP. xref: IntAct:EBI-399738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN [Term] id: CCO:I0018481 name: cdc42-was-2 direct interaction comment: surface plasma resonance : human cdc42 and human WASP xref: IntAct:EBI-457538 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0018482 name: ncbp2-eif4gi physical interaction comment: eIF4G is required for the pioneer round of translation in mammalian cells xref: IntAct:EBI-464760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN [Term] id: CCO:I0018483 name: eif4g3-ncbp1 physical interaction comment: eIF4G is required for the pioneer round of translation in mammalian cells xref: IntAct:EBI-464792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016344 ! IF4G3_HUMAN relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN [Term] id: CCO:I0018484 name: ddx48-eif4gi physical interaction comment: eIF4G is required for the pioneer round of translation in mammalian cells xref: IntAct:EBI-464796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005434 ! REN3B_HUMAN relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0063277 ! Q8NG21_HUMAN [Term] id: CCO:I0018485 name: eif4gi-q9h1j2 physical interaction comment: eIF4G is required for the pioneer round of translation in mammalian cells xref: IntAct:EBI-464801 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005434 ! REN3B_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0018486 name: ccr5-cxcr4-2 physical interaction comment: Coimmunoprecipitation of human chemokine receptor CCR5 CXR4 and CD4 in mouse fibroblast xref: IntAct:EBI-489451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0055474 ! CCR5_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:I0018487 name: eif2b1-adrb2-3 colocalization comment: Co-IP: bait= human adrenergic receptor beta 2; prey= alpha subunit of initiation factor 2B (eIF-2B) xref: IntAct:EBI-491241 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0015682 ! EI2BA_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:I0018488 name: apaf1-casp9-4 physical interaction comment: Complex formed between APAF-1 and Cytochrome C demonstrated by gel fitration xref: IntAct:EBI-517006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN [Term] id: CCO:I0018489 name: tnfrsf1a-tradd-6 physical interaction comment: GST pull down: bait = human TNFR1, prey = human TRADD xref: IntAct:EBI-518064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0018490 name: tradd-tradd-2 physical interaction comment: GST pull down : bait = human TRADD, prey = human TRADD xref: IntAct:EBI-518082 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0018491 name: birc7-casp9 physical interaction comment: The baculoviral IAP repeat-containing protein 7 (Livin) protein interacts with the Casp9 (caspase9) protein xref: IntAct:EBI-518816 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN [Term] id: CCO:I0018492 name: tac1-blys physical interaction comment: The B-lymphocyte stimulator (BlyS) protein interacts with the tumor necrosis factor receptor superfamily member TAC1 xref: IntAct:EBI-519184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0018493 name: cgi-cdh_3-1 physical interaction comment: Yeast-2-hybrid reveals interaction between the Plasminogen activator inhibitor 1 RNA-binding protein (CGI-55) and the Chromodomain helicase-DNA-binding protein 3 (CDH-3) protein xref: IntAct:EBI-523588 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:I0018494 name: hip14-snap25-3 colocalization comment: Colocalization of SNAP25 and HIP14 xref: IntAct:EBI-524992 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0055598 ! SNP25_HUMAN relationship: has_participant CCO:B0057324 ! ZDH17_HUMAN [Term] id: CCO:I0018495 name: bim-dncl2a-1 physical interaction comment: coip of human engodenous bim and dynein xref: IntAct:EBI-526424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005562 ! DLRB1_HUMAN relationship: has_participant CCO:B0006003 ! BIM_HUMAN [Term] id: CCO:I0018496 name: dicer1-eif2c2-2 physical interaction xref: IntAct:EBI-527585 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016049 ! I2C2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0018497 name: ikbkg-chuk-2 physical interaction comment: Coimmunoprecipitation reveals interaction between the NF-kappa-B essential modulator (NEMO) protein and the Inhibitor of nuclear factor kappa-B kinase alpha subunit (IKK_alpha) xref: IntAct:EBI-528461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018498 name: ikk_gamma-ikk_beta-1 physical interaction comment: Coimmunoprecipitation reveals interaction between the NF-kappa-B essential modulator (NEMO) protein and the Inhibitor of nuclear factor kappa-B kinase beta subunit (IKK_beta) xref: IntAct:EBI-528481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0018499 name: eif2c2-dicer1-1 physical interaction xref: IntAct:EBI-528584 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016049 ! I2C2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0018500 name: braf-ywhab physical interaction comment: Y2H: bait = B-Raf ,prey = 14-3-3beta xref: IntAct:EBI-537426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005913 ! BRAF1_HUMAN [Term] id: CCO:I0018501 name: braf-oip5 physical interaction comment: Y2H: bait = B-Raf ,prey = OIP5-OIP5_HUMAN xref: IntAct:EBI-537440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005913 ! BRAF1_HUMAN relationship: has_participant CCO:B0063028 ! OIP5_HUMAN [Term] id: CCO:I0018502 name: wasp-arp2-1 physical interaction comment: GST-pull down of the Arp2/3 complex by phosphorylated WASP xref: IntAct:EBI-603125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN relationship: has_participant CCO:B0021502 ! ARP3_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0018503 name: snrpa-sfpq-4 physical interaction xref: IntAct:EBI-607115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0063003 ! SNRPA_HUMAN [Term] id: CCO:I0018504 name: epor-socs2-5 physical interaction comment: Interaction between human EpoR and SOCS2 demonstrated by MAPPIT xref: IntAct:EBI-617845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0018505 name: epor-cish-6 physical interaction comment: Interaction between human EpoR and CISH demonstrated by MAPPIT xref: IntAct:EBI-617859 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055106 ! EPOR_HUMAN relationship: has_participant CCO:B0058919 ! CISH_HUMAN [Term] id: CCO:I0018506 name: arf6-arfip2-1 physical interaction comment: ARF6 interacts with POR1, as detected by gst pull down. xref: IntAct:EBI-638192 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN relationship: has_participant CCO:B0055616 ! ARF6_HUMAN [Term] id: CCO:I0018507 name: cdc42bpa-cdc42-1 direct interaction comment: Interation between CDC42BPA (MRCHalpha) and CDC42 xref: IntAct:EBI-692659 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0018508 name: atx2-cnsa3-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the ataxin-2 protein and endophilin-A3 protein xref: IntAct:EBI-697737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0018509 name: atx2-cnsa1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the ataxin-2 protein and endophilin-A1 protein xref: IntAct:EBI-697742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018510 name: rela-rela-3 physical interaction comment: Homodimerization of RelA (NF-KB p65) identified by coimunoprecipitation xref: IntAct:EBI-697798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018511 name: rela-chuk-1 physical interaction comment: Interaction of RelA (NF-KB p65) with I-kappaB alpha identified by coimmunoprecipitation xref: IntAct:EBI-697819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018512 name: cnsa1-cnsa2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the endophilin-A1 protein and endophilin-A2 protein xref: IntAct:EBI-697923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN [Term] id: CCO:I0018513 name: cnsa1-cnsa3 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the endophilin-A1 protein and endophilin-A3 protein xref: IntAct:EBI-697932 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018514 name: cnsa1-cnsa1 physical interaction comment: Directed yeast 2 hybrid analysis reveals homotypic interaction of the endophilin-A1 protein xref: IntAct:EBI-697936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018515 name: cnsa2-cnsa2 physical interaction comment: Directed yeast 2 hybrid analysis reveals homotypic interaction of the endophilin-A2 protein xref: IntAct:EBI-697940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018516 name: cnsa3-cnsa3 physical interaction comment: Directed yeast 2 hybrid analysis reveals homotypic interaction of the endophilin-A3 protein xref: IntAct:EBI-697956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0018517 name: cnsa2-cnsa3-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the endophilin-A2 protein and endophilin-A3 protein xref: IntAct:EBI-697961 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018518 name: cnsa2-cnsa1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the endophilin-A2 protein and endophilin-A1 protein xref: IntAct:EBI-697969 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN [Term] id: CCO:I0018519 name: cnsa3-cnsa1-1 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the endophilin-A3 protein and endophilin-A1 protein xref: IntAct:EBI-697973 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN [Term] id: CCO:I0018520 name: cnsa3-cnsa2 physical interaction comment: Directed yeast 2 hybrid analysis reveals interaction between the endophilin-A3 protein and endophilin-A2 protein xref: IntAct:EBI-697977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018521 name: cnas3-atx2 physical interaction comment: Directed yeast two hybrid analysis reveals competeive by ataxin-2 and huntingtin (exon 1) protein and endophillin-A3 xref: IntAct:EBI-698023 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0018522 name: itga2b-itga2b-3 direct interaction comment: Ultracentrifugation: oligomerization of alpha II b integrin xref: IntAct:EBI-702806 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:I0018523 name: phlda1-eif3s7-2 physical interaction xref: IntAct:EBI-738821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026270 ! EIF3D_HUMAN relationship: has_participant CCO:B0062957 ! PHLA1_HUMAN [Term] id: CCO:I0018524 name: tom1-tollip-3 physical interaction comment: Interaction between Tom1 and Tollip - demonstrated by coimmunoprecipitation xref: IntAct:EBI-74643 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0063278 ! TOM1_HUMAN [Term] id: CCO:I0018525 name: adam9-pacsin3-3 physical interaction xref: IntAct:EBI-78013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0018526 name: mapk8ip1-app-4 direct interaction comment: mapk8ip1(hJIP1)- APP FRET xref: IntAct:EBI-78806 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0059280 ! JIP1_HUMAN [Term] id: CCO:I0018527 name: ncoa3-chuk physical interaction xref: IntAct:EBI-81320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0018528 name: pole3-pole4-5 physical interaction comment: Interaction between POLE2, POLE3 and POLE4 identified by coimmunoprecipitation xref: IntAct:EBI-867134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN relationship: has_participant CCO:B0005905 ! DPOE4_HUMAN [Term] id: CCO:I0018529 name: erbb3-erbb2-2 physical interaction comment: Interaction between human erbB3 and erbB2 detected by coIP xref: IntAct:EBI-875500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN [Term] id: CCO:I0018530 name: p85a-erbb3-3 physical interaction comment: Interaction between human P85A and erbB3 detected by coIP xref: IntAct:EBI-875572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0018531 name: trrap-err1 direct interaction comment: Direct interaction determined by pull down. xref: IntAct:EBI-896538 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0038838 ! ERR1_HUMAN [Term] id: CCO:I0018532 name: smarce1-rest physical interaction comment: Co-IP: bait = BAF57, prey = REST xref: IntAct:EBI-926716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0055876 ! REST_HUMAN [Term] id: CCO:I0018533 name: smarca4-rest physical interaction comment: Co-IP: bait = BRG1, prey = rest xref: IntAct:EBI-926720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0055876 ! REST_HUMAN [Term] id: CCO:I0018534 name: smarcc2-rest physical interaction comment: Co-IP: bait = BAF170, prey = rest xref: IntAct:EBI-926725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0055876 ! REST_HUMAN [Term] id: CCO:I0018535 name: smarca4-rest-1 physical interaction comment: Co-IP: bait =rest, prey = BRG1 xref: IntAct:EBI-926730 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0055876 ! REST_HUMAN [Term] id: CCO:I0018536 name: smarca4-rcor1 physical interaction comment: Co-IP: bait = BRG1, prey = coREST xref: IntAct:EBI-926734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0059194 ! RCOR1_HUMAN [Term] id: CCO:I0018537 name: smarcc2-rcor1 physical interaction comment: Co-IP: bait = BAF170, prey = coREST xref: IntAct:EBI-926738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0059194 ! RCOR1_HUMAN [Term] id: CCO:I0018538 name: hdac1-rcor1 physical interaction comment: Co-IP: bait = coREST, preys = HDAC1, HDAC2 xref: IntAct:EBI-926742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0059194 ! RCOR1_HUMAN [Term] id: CCO:I0018539 name: hdac1-smarce1 physical interaction comment: Co-IP: bait = BAF57, preys = HDAC1, HDAC2 xref: IntAct:EBI-926747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0018540 name: hdac1-smarca4 physical interaction comment: Co-IP: bait = BRG1, prey = HDAC1, HDAC2 xref: IntAct:EBI-926752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0018541 name: hdac1-smarcc2 physical interaction comment: Co-IP: bait = BAF170, preys = HDAC1, HDAC2 xref: IntAct:EBI-926757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0018542 name: baz1a-baz1b-1 physical interaction xref: IntAct:EBI-928574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058901 ! BAZ1A_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0018543 name: disc1-eif3s3-1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and EIF3S3 protein xref: IntAct:EBI-929006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0018544 name: disc1-atf4 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and ATF4 protein xref: IntAct:EBI-929009 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0021435 ! ATF4_HUMAN [Term] id: CCO:I0018545 name: disc1-rassf7 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and RASSF7 protein xref: IntAct:EBI-929031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0055716 ! RASF7_HUMAN [Term] id: CCO:I0018546 name: disc1-spectrin physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and Beta-4-Spectrin protein xref: IntAct:EBI-929063 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0058677 ! SPTN4_HUMAN [Term] id: CCO:I0018547 name: nkx2_5-camta2 colocalization xref: IntAct:EBI-936618 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0054714 ! CMTA2_HUMAN relationship: has_participant CCO:B0055506 ! NKX25_HUMAN [Term] id: CCO:I0018548 name: hash1-e2_2-4 physical interaction comment: Interaction between human HASH-1 and E2-2 detected by pulldown xref: IntAct:EBI-957274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018549 name: hash1-e47-2 physical interaction comment: Interaction between human HASH-1 and E47 detected by pulldown xref: IntAct:EBI-957282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018550 name: hash1-e2_2-5 physical interaction comment: Interaction between human HASH-1 and E2-2 detected by pulldown xref: IntAct:EBI-957290 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0018551 name: pilra-ptpn6-1 physical interaction xref: IntAct:EBI-965900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0015779 ! PILRA_HUMAN [Term] id: CCO:I0018552 name: birc2-traf2-2 physical interaction comment: Interaction between BIRC2 (cIAP1) and TRAF2 identified by pulldown xref: IntAct:EBI-977048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN [Term] id: CCO:I0018553 name: birc3-traf2-1 physical interaction comment: Interaction between BIRC3 (cIAP2) and TRAF2 identified by pulldown xref: IntAct:EBI-977061 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0055917 ! BIRC3_HUMAN [Term] id: CCO:I0018554 name: birc3-traf2-3 physical interaction comment: Interaction between BIRC3 (cIAP2) and TRAF2 identified by pulldown xref: IntAct:EBI-977140 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0055917 ! BIRC3_HUMAN [Term] id: CCO:I0018555 name: rela-atf3 direct interaction xref: IntAct:EBI-981345 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN [Term] id: CCO:I0018556 name: rela-atf3-1 direct interaction xref: IntAct:EBI-981395 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN [Term] id: CCO:I0018557 name: rela-cbp direct interaction xref: IntAct:EBI-981475 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018558 name: rela-cbp-1 physical interaction xref: IntAct:EBI-981537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN [Term] id: CCO:I0018559 name: serpina1-ela2-1 direct interaction comment: Interaction between SERPINA1 and ELA2 demonstrated by in gel xref: IntAct:EBI-986375 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0028166 ! A1AT_HUMAN relationship: has_participant CCO:B0054926 ! ELNE_HUMAN [Term] id: CCO:I0018560 name: rma1-cftr-2 physical interaction xref: IntAct:EBI-988795 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0058523 ! DERL1_HUMAN [Term] id: CCO:I0018561 name: rma1-cftr-3 physical interaction xref: IntAct:EBI-988809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN relationship: has_participant CCO:B0058523 ! DERL1_HUMAN [Term] id: CCO:I0018562 name: rma1-cftr-4 physical interaction xref: IntAct:EBI-988819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN relationship: has_participant CCO:B0058523 ! DERL1_HUMAN [Term] id: CCO:I0018563 name: hsf1-mk2 physical interaction xref: IntAct:EBI-993295 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026467 ! HSF1_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:I0018564 name: cxorf40a-mt2a-1 physical interaction xref: IntAct:EBI-996630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063264 ! CX04A_HUMAN [Term] id: CCO:I0018565 name: tmed10-psen1-5 physical interaction xref: IntAct:EBI-999038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0038128 ! TMED2_HUMAN relationship: has_participant CCO:B0058062 ! NICA_HUMAN relationship: has_participant CCO:B0058989 ! PEN2_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0018566 name: adam15-pacsin3-1 physical interaction xref: IntAct:EBI-77845 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005909 ! ADA15_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0018567 name: accn1-prkcabp-2 physical interaction xref: IntAct:EBI-79206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0063267 ! ACCN1_HUMAN [Term] id: CCO:I0018568 name: eif4g1-eif4a1-2 physical interaction comment: Interaction of eIF4AI and eIF4G1 identified by coimmunoprecipitation xref: IntAct:EBI-73469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0018569 name: hadh2-app-1 physical interaction comment: ERAB-amyloid beta y2h xref: IntAct:EBI-79985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063213 ! HCD2_HUMAN [Term] id: CCO:I0018570 name: eif4g1-eif4a1-1 physical interaction comment: Interaction of eIF4G1 with eIF4AI identified by coimmunoprecipitation xref: IntAct:EBI-73718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005679 ! IF4A1_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0018571 name: eif4g1-eif4a2-1 physical interaction comment: Interaction of eIF4GI with eIF4AII identified by coimmunoprecipitation xref: IntAct:EBI-73482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0018572 name: adam15-sh3gl2-1 physical interaction xref: IntAct:EBI-77950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005909 ! ADA15_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018573 name: mapk8ip1-app-1 physical interaction comment: mapk8ip1-app in vitro xref: IntAct:EBI-78430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0059280 ! JIP1_HUMAN [Term] id: CCO:I0018574 name: dnajc1-mt1h-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-296562 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058258 ! DNJC1_HUMAN relationship: has_participant CCO:B0063279 ! MT1H_HUMAN [Term] id: CCO:I0018575 name: st7-actn2-1 physical interaction comment: Interaction between ST7 and ACTN2 detected by Y2H xref: IntAct:EBI-296713 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0059369 ! LRP12_HUMAN [Term] id: CCO:I0018576 name: st7-ttid-1 physical interaction comment: Interaction between ST7 and TTID detected by Y2H xref: IntAct:EBI-296720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059369 ! LRP12_HUMAN relationship: has_participant CCO:B0063280 ! MYOTI_HUMAN [Term] id: CCO:I0018577 name: st7-snap25bp-1 physical interaction comment: Interaction between ST7 and SNAP25BP detected by Y2H xref: IntAct:EBI-296734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043870 ! SNAPN_HUMAN relationship: has_participant CCO:B0059369 ! LRP12_HUMAN [Term] id: CCO:I0018578 name: btz-eif4aiii physical interaction comment: An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay xref: IntAct:EBI-299122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0063246 ! CASC3_HUMAN [Term] id: CCO:I0018579 name: mapk11-sp1-1 physical interaction comment: Various proteins interacting with MAPK 11 were determined by CoIP xref: IntAct:EBI-298442 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005485 ! SP1_HUMAN relationship: has_participant CCO:B0005632 ! MYB_HUMAN relationship: has_participant CCO:B0005823 ! K2C1_HUMAN relationship: has_participant CCO:B0005892 ! MK11_HUMAN [Term] id: CCO:I0018580 name: xab2-ckn1-1 physical interaction comment: Interaction detected by GST-pull down. xref: IntAct:EBI-295270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041548 ! SYF1_HUMAN relationship: has_participant CCO:B0055887 ! ERCC8_HUMAN [Term] id: CCO:I0018581 name: ckn1-xab2-1 physical interaction comment: Interaction detected by GST-pull down. xref: IntAct:EBI-295274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041548 ! SYF1_HUMAN relationship: has_participant CCO:B0055887 ! ERCC8_HUMAN [Term] id: CCO:I0018582 name: dach-madh4-2 physical interaction xref: IntAct:EBI-347306 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN [Term] id: CCO:I0018583 name: madh4-ski-1 physical interaction xref: IntAct:EBI-347309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0055004 ! SKI_HUMAN [Term] id: CCO:I0018584 name: dach-madh4-3 physical interaction xref: IntAct:EBI-347322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN [Term] id: CCO:I0018585 name: fkbp5-chuk physical interaction comment: IKKalpha with fkb5 co-ip xref: IntAct:EBI-353526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0063039 ! FKBP5_HUMAN [Term] id: CCO:I0018586 name: rit-af6 physical interaction comment: Interactions of human Rit identified by Y2H xref: IntAct:EBI-365909 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0005914 ! AFAD_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN [Term] id: CCO:I0018587 name: rit2-af6 physical interaction comment: Interactions of human Rit2 identified by Y2H xref: IntAct:EBI-365913 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0005914 ! AFAD_HUMAN relationship: has_participant CCO:B0058426 ! RIT2_HUMAN [Term] id: CCO:I0018588 name: prkcq-txnl2-2 physical interaction comment: Interaction between PKCtheta and TXNL2 confirmed by coimmunoprecipitation xref: IntAct:EBI-374803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0062932 ! GLRX3_HUMAN [Term] id: CCO:I0018589 name: cbfb-p32-3 colocalization comment: Colocalisation of CBFB and p32 demonstrated by immunostaining xref: IntAct:EBI-389829 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN [Term] id: CCO:I0018590 name: map3k1-map2k4-2 phosphorylation comment: Activation of MAP2K4 by MAP3K1 xref: IntAct:EBI-447893 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN [Term] id: CCO:I0018591 name: rac1-dock1-4 physical interaction comment: Interaction detected by co IP, bait = human GST- Rac, prey =human Dock180 xref: IntAct:EBI-448750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0018592 name: rac1-dock2-1 physical interaction comment: Interaction detected by co IP, bait = human GST- Rac, prey =human dock2 xref: IntAct:EBI-448768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0063281 ! DOCK2_HUMAN [Term] id: CCO:I0018593 name: eea1-rab5b-2 physical interaction comment: Analysis of EEA1/Rab5b interaction in vitro. xref: IntAct:EBI-399426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023553 ! RAB5B_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0018594 name: eea1-rab5b-3 colocalization comment: Colocalization of Rab5b and EEA1. xref: IntAct:EBI-399434 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0023553 ! RAB5B_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0018595 name: tceb2-med8-1 physical interaction comment: interaction detected by Y2H in yeast expressing EloC xref: IntAct:EBI-398484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0018596 name: tceb1-med8-1 physical interaction comment: interaction detected by Y2H in yeast expressing EloC xref: IntAct:EBI-398497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0018597 name: tceb2-med8-2 physical interaction comment: interaction detected by Y2H in yeast expressing EloC xref: IntAct:EBI-398502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0018598 name: p28b-p28b-1 physical interaction comment: Interaction detected by FLAG IP xref: IntAct:EBI-398695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005787 ! MED18_HUMAN [Term] id: CCO:I0018599 name: map3k4-1 physical interaction comment: Self interaction of MAP3K4 - interacting domains defined by Y2H xref: IntAct:EBI-448214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005915 ! M3K4_HUMAN [Term] id: CCO:I0018600 name: gemin5-gemin4-1 physical interaction comment: Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. xref: IntAct:EBI-443659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006110 ! SMN_HUMAN relationship: has_participant CCO:B0059141 ! DDX20_HUMAN relationship: has_participant CCO:B0062979 ! GEMI5_HUMAN relationship: has_participant CCO:B0063087 ! GEMI4_HUMAN relationship: has_participant CCO:B0063282 ! GEMI2_HUMAN [Term] id: CCO:I0018601 name: gemin5-smn1-1 physical interaction comment: Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. xref: IntAct:EBI-443665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006110 ! SMN_HUMAN relationship: has_participant CCO:B0059141 ! DDX20_HUMAN [Term] id: CCO:I0018602 name: rfc2-prkar1a-4 physical interaction xref: IntAct:EBI-476509 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0018603 name: rfc2-prkar1a-5 physical interaction xref: IntAct:EBI-476544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0018604 name: rfc2-prkar1a-6 physical interaction xref: IntAct:EBI-476561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0018605 name: insr-crkl-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-475939 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0055377 ! CRKL_HUMAN [Term] id: CCO:I0018606 name: rfc2-rfc4-2 physical interaction xref: IntAct:EBI-476672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0018607 name: rfc2-rfc4-3 physical interaction xref: IntAct:EBI-476677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0018608 name: insr-crkl-2 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-476017 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0055377 ! CRKL_HUMAN [Term] id: CCO:I0018609 name: tnfsf10-casp10-1 physical interaction comment: Components of the TRAIL DISC xref: IntAct:EBI-495399 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0018610 name: tnfsf6-casp10-2 physical interaction comment: Components of the Fas DISC xref: IntAct:EBI-495412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0018611 name: gab1-ptpn11-3 physical interaction comment: Interaction of Gab1 and Shp-2 identified by Y2H xref: IntAct:EBI-517754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055765 ! PTN11_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN [Term] id: CCO:I0018612 name: tnfrsf1a-tradd-2 physical interaction comment: yeast 2-hybrid: bait = human TNFR1, prey = human TRADD xref: IntAct:EBI-518009 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0018613 name: casp8-ripk1-1 physical interaction comment: coIp: bait=caspase-8, prey= RIP1 xref: IntAct:EBI-515198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0018614 name: tradd-tradd-1 physical interaction comment: yeast 2-hybrid: bait = human TRADD, prey = human TRADD xref: IntAct:EBI-518042 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0018615 name: bclxl-biml-1 physical interaction comment: coip of bcl-xl with bim and endogenous dynein xref: IntAct:EBI-526396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005562 ! DLRB1_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0018616 name: apaf1-casp9-3 physical interaction comment: Complex formed between APAF-1 and Cytochrome C demonstrated by gel fitration xref: IntAct:EBI-516878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN [Term] id: CCO:I0018617 name: casp2-cradd-6 physical interaction comment: In vivo Co-IP: bait= human caspase 2, prey = human RAIDD xref: IntAct:EBI-520531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN [Term] id: CCO:I0018618 name: traf6-tiz-2 colocalization comment: Confocal microscopy reveals interaction between the TNF receptor associated factor 6 (TRAF6) protein and the TRAF6-binding zinc finger protein xref: IntAct:EBI-528249 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN [Term] id: CCO:I0018619 name: mihb-diablo physical interaction comment: The mihb protein interacts with the diablo protein xref: IntAct:EBI-517695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018620 name: mihc-diablo physical interaction comment: The mihc protein interacts with the diablo protein xref: IntAct:EBI-517726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055917 ! BIRC3_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0018621 name: chuk-map3k14-2 phosphorylation comment: Phosphorylation of CHUK (I-kappa kinase alpha) by MAP3K14 (NIK) xref: IntAct:EBI-961615 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018622 name: app-nsf-3 physical interaction comment: Interacting partners of human APP from brains samples derived from Alzheimers patients xref: IntAct:EBI-960581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:I0018623 name: gch1-hsc70 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between GCH1 protein and HSc70 protein xref: IntAct:EBI-958233 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0050722 ! GCH1_HUMAN [Term] id: CCO:I0018624 name: gch1-rab26 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between GCH1 protein and Rab26 protein xref: IntAct:EBI-958249 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0059236 ! RAB26_HUMAN [Term] id: CCO:I0018625 name: gch1-cb1_1p1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between GCH1 protein and CB1-1P1 protein xref: IntAct:EBI-958260 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0063262 ! CNRP1_HUMAN [Term] id: CCO:I0018626 name: gch1-rlf physical interaction comment: Yeast 2 hybrid analysis reveals interaction between GCH1 protein and RFL protein xref: IntAct:EBI-958275 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0055877 ! RLF_HUMAN [Term] id: CCO:I0018627 name: gch1-aha1 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between GCH1 protein and Aha1protein xref: IntAct:EBI-958210 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0063014 ! AHSA1_HUMAN [Term] id: CCO:I0018628 name: chuk-nfkbia-1 phosphorylation comment: Phosphorylation of I-kappa B alpha by CHUK (I-kappa kinase alpha) xref: IntAct:EBI-961463 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018629 name: ikbkb-nfkbia-2 phosphorylation comment: Phosphorylation of I-kappa B alpha by I-kappa kinase beta xref: IntAct:EBI-961478 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN [Term] id: CCO:I0018630 name: ikbkb-chuk-1 physical interaction comment: Interaction between IKBKB and CHUK demonstrated by coimmunoprecipitation xref: IntAct:EBI-961495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018631 name: chuk-map3k14-1 phosphorylation comment: Phosphorylation of CHUK (I-kappa kinase alpha) by MAP3K14 (NIK) xref: IntAct:EBI-961503 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018632 name: ikbkb-map3k1-1 phosphorylation comment: Phosphorylation of IKBKB (I-kappa kinase beta) by MAP3K1 (MEKK1) xref: IntAct:EBI-961595 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN [Term] id: CCO:I0018633 name: trm61-trm6-1 physical interaction xref: IntAct:EBI-934057 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059170 ! TRM6_HUMAN relationship: has_participant CCO:B0063283 ! TRM61_HUMAN [Term] id: CCO:I0018634 name: atxn1-ubqln4 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between Ataxin-1 protein and Ubiquilin-4 protein xref: IntAct:EBI-930979 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018635 name: atxn1-ubqln4-2 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between Ataxin-1 protein and Ubiquilin-4 protein xref: IntAct:EBI-931004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018636 name: atxn1-atxn1 physical interaction comment: Yeast 2 hybrid analysis reveals homotypic association of the Ataxin-1 protein xref: IntAct:EBI-944335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0018637 name: baz2a-fbl colocalization xref: IntAct:EBI-934912 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005722 ! FBRL_HUMAN relationship: has_participant CCO:B0059160 ! BAZ2A_HUMAN [Term] id: CCO:I0018638 name: baz1b-polr1a colocalization xref: IntAct:EBI-935042 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0049473 ! RPA2_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0018639 name: smarca5-polr1a colocalization xref: IntAct:EBI-935049 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0049473 ! RPA2_HUMAN relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN [Term] id: CCO:I0018640 name: hdac2-rfx5 physical interaction xref: IntAct:EBI-923295 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005807 ! SIN3B_HUMAN relationship: has_participant CCO:B0055402 ! RFX5_HUMAN [Term] id: CCO:I0018641 name: hdac2-rfx5-1 physical interaction xref: IntAct:EBI-923305 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005807 ! SIN3B_HUMAN relationship: has_participant CCO:B0055402 ! RFX5_HUMAN [Term] id: CCO:I0018642 name: disc1-eif3s3-3 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the DISC1 protein and EIF3S3 protein xref: IntAct:EBI-929171 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN [Term] id: CCO:I0018643 name: stk25-ywhaz -2 phosphorylation comment: Phosphorylation of YWHAZ by Ysk1 xref: IntAct:EBI-618413 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0022748 ! STK25_HUMAN [Term] id: CCO:I0018644 name: zn655-vav1-3 physical interaction comment: Interaction between ZN655 (VIK) and VAV1 confirmed by GST pulldown xref: IntAct:EBI-625621 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005578 ! ZN655_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:I0018645 name: grb2-vav1-1 physical interaction comment: Interaction between Grb2 and VAV1 confirmed by GST pulldown xref: IntAct:EBI-625630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN [Term] id: CCO:I0018646 name: mst4-mst4-4 phosphorylation comment: Autophosphorylation of Mst4 xref: IntAct:EBI-620781 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:I0018647 name: epor-plcg21-1 physical interaction comment: Interaction between human EpoR and PLCgamma2 demonstrated by MAPPIT xref: IntAct:EBI-617396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055061 ! PLCG2_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0018648 name: ccr1-plp2-1 physical interaction comment: Interaction of CCR1 and PLP2 detected by Y2H. xref: IntAct:EBI-608343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055740 ! PLP2_HUMAN [Term] id: CCO:I0018649 name: dyrk1b-map2k3-2 phosphorylation comment: Phosphorylation of DYRK1B by MAP2K3 identified by in vitro kinase assay xref: IntAct:EBI-636016 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0020948 ! MP2K3_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0018650 name: dyrk1b-tcf1-2 phosphorylation comment: Phosphorylation of TCF1 (HNF1alpha) by DYRK1B identified by in vitro kinase assay xref: IntAct:EBI-636072 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:I0018651 name: rac1-arfip2 physical interaction comment: Interaction between RAC1 and POR1 detected by liquid beta-dalactosidase assay. xref: IntAct:EBI-641553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018652 name: arf6-arfip2-3 physical interaction comment: Interaction between ARF6 and POR1 detected by liquid beta-dalactosidase assay. xref: IntAct:EBI-641579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN relationship: has_participant CCO:B0055616 ! ARF6_HUMAN [Term] id: CCO:I0018653 name: rbpsuh-ncor2-3 physical interaction comment: Interaction of SKIP and CBF-1, detected by yeast two hybrid. xref: IntAct:EBI-636331 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN [Term] id: CCO:I0018654 name: notch1-skip-1 physical interaction comment: Interaction of Notch1IC and SKIP, detected by mammalian two hybrid. xref: IntAct:EBI-636469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:I0018655 name: cir-u2af1-2 physical interaction comment: CIR interacts with SR proteins, as detected by mammalian coip. xref: IntAct:EBI-632490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:I0018656 name: cir-sfrs2-2 physical interaction comment: CIR interacts with SR proteins, as detected by mammalian coip. xref: IntAct:EBI-632497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:I0018657 name: cir-sfrs1-3 physical interaction comment: CIR interacts with SR proteins, as detected by mammalian coip. xref: IntAct:EBI-632504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0018658 name: cir-sfrs2-3 physical interaction comment: CIR interacts with SR proteins, as detected by mammalian coip. xref: IntAct:EBI-632512 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:I0018659 name: cir-u2af1-3 physical interaction comment: CIR interacts with SR proteins, as detected by mammalian coip. xref: IntAct:EBI-632519 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:I0018660 name: cir-sfrs1-2 physical interaction comment: CIR interacts with SR proteins, as detected by mammalian coip. xref: IntAct:EBI-632543 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005487 ! SFRS1_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0018661 name: arf6-arfip2-2 physical interaction comment: Interaction between ARF6 and POR1 detected by yeast two-hybrid. xref: IntAct:EBI-640595 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN relationship: has_participant CCO:B0055616 ! ARF6_HUMAN [Term] id: CCO:I0018662 name: rac1-arfip2-1 physical interaction comment: Interaction of Rac1 and POR1 detected by yeast two hybrid. xref: IntAct:EBI-640616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018663 name: arfip2-arf6-3 physical interaction comment: ARF6 binds to the C-terminus of POR1, as detected by yeast two hybrid. xref: IntAct:EBI-640619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN relationship: has_participant CCO:B0055616 ! ARF6_HUMAN [Term] id: CCO:I0018664 name: arf3-arfip2-1 physical interaction comment: Interaction of ARF3 and POR1, as detected by yeast two hybrid. xref: IntAct:EBI-640718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015284 ! ARF3_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018665 name: fgf-fgfr-4 direct interaction comment: Interaction between FGFR3 immunoglobulin domains determined by surface plasmon resonance xref: IntAct:EBI-698294 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0018666 name: hsp1-hsp4-7 physical interaction comment: Co-sedimentation of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0018667 name: atx2-pabp-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the ataxin-2 protein and PABP protein xref: IntAct:EBI-698732 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0018668 name: hsp1-hsp4-13 physical interaction comment: Co-sedimentation of HA-HPS1 and myc-HPS4 xref: IntAct:EBI-704536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0018669 name: atx2-cnsa1-2 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the ataxin-2 protein and endophilin-A1 protein xref: IntAct:EBI-697879 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0018670 name: atx2-cnsa3-3 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the ataxin-2 protein and endophilin--A3 protein xref: IntAct:EBI-697892 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0018671 name: ikka-src-2 physical interaction comment: cSRC is a component of the IKK complex xref: IntAct:EBI-697929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018672 name: ikka-src-1 physical interaction comment: cSRC is a component of the IKK complex xref: IntAct:EBI-697951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005539 ! IKKA_HUMAN [Term] id: CCO:I0018673 name: eif4g1-eif4a2-2 physical interaction comment: Interaction of eIF4GI and eIF4AII identified by coimmunoprecipitation xref: IntAct:EBI-73723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0018674 name: app-apoa1-2 physical interaction comment: Apolipoprotein A-1 interacts with the extracellular domain of the Amyloid Precursor protein, detected by yeast two hybrid. xref: IntAct:EBI-703748 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN [Term] id: CCO:I0018675 name: pim1-bmx-6 physical interaction comment: Interaction between PIM1 and BMX identified by coimmunoprecipitation xref: IntAct:EBI-783036 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005923 ! BMX_HUMAN relationship: has_participant CCO:B0022781 ! PIM1_HUMAN [Term] id: CCO:I0018676 name: abca1-sntb1 physical interaction comment: Far western blotting assay reveals ABCA1 interacts with beta-1-syntrophin. xref: IntAct:EBI-784204 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0063266 ! SNTB1_HUMAN [Term] id: CCO:I0018677 name: flna-flnb-1 physical interaction comment: Y2H: bait = Filamin A, prey = Filamin B xref: IntAct:EBI-851975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018678 name: flna-flnb-2 physical interaction comment: Y2H: bait = Filamin A, prey = Filamin B xref: IntAct:EBI-851995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018679 name: flnb-flnb-1 physical interaction comment: Y2H: bait = Filamin B, prey = Filamin B xref: IntAct:EBI-852003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018680 name: flnb-flnb-2 physical interaction comment: Y2H: bait = Filamin B, prey = Filamin B xref: IntAct:EBI-852020 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018681 name: flna-flnb-3 physical interaction comment: Y2H: bait = Filamin A, prey = Filamin B xref: IntAct:EBI-852028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018682 name: flna-flnb-4 physical interaction comment: Y2H: bait = Filamin A, prey = Filamin B xref: IntAct:EBI-852036 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018683 name: flnb-flnb-4 physical interaction comment: Y2H: bait = Filamin B, prey = Filamin B xref: IntAct:EBI-852060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018684 name: flnb-flnb-3 physical interaction comment: Y2H: bait = Filamin B, prey = Filamin B xref: IntAct:EBI-852052 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0018685 name: traf6-map3k14-1 physical interaction comment: Interaction between TRAF6 and MAP3K14 (NIK) demonstrated by coimmunoprecipitation xref: IntAct:EBI-961633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0018686 name: traf6-map3k14-2 physical interaction comment: Interaction between IL1R1 , TRAF6 and MAP3K14 (NIK) demonstrated by coimmunoprecipitation xref: IntAct:EBI-961642 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN relationship: has_participant CCO:B0005528 ! M3K14_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0018687 name: traf6-il1r1-1 physical interaction comment: Interaction between IL1R1 and TRAF6 demonstrated by coimmunoprecipitation xref: IntAct:EBI-961651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN [Term] id: CCO:I0018688 name: dicer1-tarbp2-4 physical interaction xref: IntAct:EBI-979922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0018689 name: dicer1-tarbp2-6 physical interaction xref: IntAct:EBI-981015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0018690 name: gsk3b-akt1-1 phosphorylation comment: Phosphorylation of GSK3beta by AKT1 xref: IntAct:EBI-963017 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN [Term] id: CCO:I0018691 name: err1-trrap-1 physical interaction comment: Interaction detected by pulldown xref: IntAct:EBI-896407 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0038838 ! ERR1_HUMAN relationship: has_participant CCO:B0058748 ! MYST1_HUMAN [Term] id: CCO:I0018692 name: err1-trrap-2 physical interaction comment: Interaction detected by pulldown. xref: IntAct:EBI-896469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0038838 ! ERR1_HUMAN relationship: has_participant CCO:B0058748 ! MYST1_HUMAN [Term] id: CCO:I0018693 name: rps6ka1-creb1-1 phosphorylation comment: Phosphorylation of RPS6KA1 by CREB1 xref: IntAct:EBI-963054 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0028627 ! KS6A1_HUMAN [Term] id: CCO:I0018694 name: gsk3b-gys-1 phosphorylation comment: Phosphorylation of GYS ((muscle) by GSK3beta xref: IntAct:EBI-963104 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0063284 ! GYS1_HUMAN [Term] id: CCO:I0018695 name: sphk2-fyn-1 direct interaction comment: Interaction between Sphk2 and Fyn demonstrated by coimmunoprecipitation xref: IntAct:EBI-985356 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0036431 ! SPHK2_HUMAN [Term] id: CCO:I0018696 name: sphk2-lyn-1 direct interaction comment: Interaction between Sphk2 and Lyn demonstrated by coimmunoprecipitation xref: IntAct:EBI-985362 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0036431 ! SPHK2_HUMAN [Term] id: CCO:I0018697 name: tmed10-psen1 physical interaction xref: IntAct:EBI-998506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0058062 ! NICA_HUMAN relationship: has_participant CCO:B0058989 ! PEN2_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0018698 name: mbd1-cbx5-1 physical interaction xref: IntAct:EBI-994645 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0018699 name: mbd1-hdac1-3 physical interaction xref: IntAct:EBI-994809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0018700 name: mbd1-hdac2-3 physical interaction xref: IntAct:EBI-994861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0018701 name: morf4l2-hdac1-1 physical interaction xref: IntAct:EBI-995834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0018702 name: pum2-daz1-1 physical interaction xref: IntAct:EBI-997951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0024383 ! PUM2_HUMAN [Term] id: CCO:I0018703 name: gtf2f1-gtf2f2-1 direct interaction comment: Crystal structure of the rap30-74 interaction domains of human tfiif xref: IntAct:EBI-1030578 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005354 ! T2FA_HUMAN relationship: has_participant CCO:B0020975 ! T2FB_HUMAN [Term] id: CCO:I0018704 name: arhgef12-rhoa-1 direct interaction comment: Crystal structure of the dh-ph domains of leukemia- assiociated rhogef in complex with rhoa xref: IntAct:EBI-1040240 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0059006 ! ARHGC_HUMAN [Term] id: CCO:I0018705 name: rab5a-rabep1-1 direct interaction comment: Crystal structure of rab5 complex with rabaptin5 c-terminal domain xref: IntAct:EBI-1040324 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0023551 ! RAB5A_HUMAN relationship: has_participant CCO:B0063285 ! RABE1_HUMAN [Term] id: CCO:I0018706 name: klrk1-ulbp3-1 direct interaction comment: Nkg2d in complex with ulbp3 xref: IntAct:EBI-1032569 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0020491 ! N2DL3_HUMAN relationship: has_participant CCO:B0055192 ! NKG2D_HUMAN [Term] id: CCO:I0018707 name: cd40-traf6-2 direct interaction comment: Traf6-cd40 complex xref: IntAct:EBI-1033939 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0055188 ! TNR5_HUMAN [Term] id: CCO:I0018708 name: fnta-fntb-16 direct interaction comment: Human protein farnesyltransferase complexed with l-778,123 and fpp xref: IntAct:EBI-1039460 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:I0018709 name: arhgef11-rhoa-1 direct interaction comment: Crystal structure of human rhoa in complex with dh-ph fragment of pdzrhogef xref: IntAct:EBI-1040765 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN [Term] id: CCO:I0018710 name: hba1-hbb-8 direct interaction comment: Cyanomet hemoglobin (a-gly-c:v1m,l29f,h58q; b,d:v1m,l106w) xref: IntAct:EBI-1026804 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018711 name: bckdha-bckdhb-9 direct interaction comment: Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1041243 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018712 name: bckdha-bckdhb-10 direct interaction comment: Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1041254 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018713 name: bckdha-bckdhb-11 direct interaction comment: Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1041265 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018714 name: bckdha-bckdhb-12 direct interaction comment: Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1041276 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018715 name: bckdha-bckdhb-13 direct interaction comment: Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1041287 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018716 name: bckdha-bckdhb-14 direct interaction comment: Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase xref: IntAct:EBI-1041298 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0063238 ! ODBB_HUMAN [Term] id: CCO:I0018717 name: cftr-nhe2 physical interaction xref: IntAct:EBI-1107976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0020193 ! SL9A2_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN [Term] id: CCO:I0018718 name: esr1-foxo1a-1 physical interaction xref: IntAct:EBI-1108856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0016881 ! FOXO1_HUMAN [Term] id: CCO:I0018719 name: esr1-foxo1a-2 physical interaction xref: IntAct:EBI-1108892 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN [Term] id: CCO:I0018720 name: gsk3b-nin-2 phosphorylation comment: Phosphorylation of NIN by GSK3B xref: IntAct:EBI-1164249 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0062970 ! NIN_HUMAN [Term] id: CCO:I0018721 name: smarca2-c20orf14 physical interaction xref: IntAct:EBI-1168688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0054708 ! PRP6_HUMAN [Term] id: CCO:I0018722 name: fyn-htr6-5 physical interaction comment: Interaction between HTR6 and FYN identified by coimmunoprecipitation xref: IntAct:EBI-1182294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:I0018723 name: fyn-htr6-6 physical interaction comment: Interaction between HTR6 and FYN identified by coimmunoprecipitation xref: IntAct:EBI-1182305 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:I0018724 name: spink7-mt2a physical interaction comment: ECRG2 interacts with MT2A in a yeast two hybrid assay xref: IntAct:EBI-1182455 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0062971 ! ISK7_HUMAN [Term] id: CCO:I0018725 name: spink7-ebp42 physical interaction comment: ECRG2 interacts with EMBP4.2 in a yeast two hybrid assay xref: IntAct:EBI-1182523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055051 ! EPB42_HUMAN relationship: has_participant CCO:B0062971 ! ISK7_HUMAN [Term] id: CCO:I0018726 name: wnk3-casp3-1 physical interaction comment: Interaction between WNK3 and Caspase-3 identified by antibody array xref: IntAct:EBI-1182594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055351 ! CASP3_HUMAN relationship: has_participant CCO:B0058581 ! WNK3_HUMAN [Term] id: CCO:I0018727 name: mt2a-prkd1-1 physical interaction comment: PKCmu coimmunoprecipitates with MT 2A in C4-2 cells xref: IntAct:EBI-1181167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:I0018728 name: fyn-med28-3 physical interaction comment: Interaction between Fyn and MED28 identified by coimmunoprecipitation xref: IntAct:EBI-1206846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005468 ! MED28_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0018729 name: eed-hdac1 physical interaction xref: IntAct:EBI-1204362 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0043864 ! EED_HUMAN [Term] id: CCO:I0018730 name: parp1-g22p1 physical interaction comment: Ku70 and Ku80 coimmunoprecipitate with PARP1 in HCT116 nuclear extract xref: IntAct:EBI-1201315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0018731 name: stk3-sav1-3 phosphorylation comment: Phosphorylation of SAV1 by STK3 (MST2) xref: IntAct:EBI-1025440 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0055885 ! STK3_HUMAN relationship: has_participant CCO:B0058715 ! SAV1_HUMAN [Term] id: CCO:I0018732 name: hba1-hbb-1 direct interaction comment: Deoxy hemoglobin (a-gly-c:v1m,l29f,h58q; b,d:v1m,l106w) xref: IntAct:EBI-1025826 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018733 name: hba1-hbb-2 direct interaction comment: Deoxy hemoglobin (a,c:v1m; b,d:v1m,v67w) xref: IntAct:EBI-1025836 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018734 name: hba1-hbb-3 direct interaction comment: Deoxy hemoglobin (a-gly-c:v1m,l29w,h58q; b,d:v1m) xref: IntAct:EBI-1025847 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018735 name: hba1-hbb-4 direct interaction comment: Deoxy hemoglobin (a-glyglygly-c:v1m,l29f,h58q b,d:v1m,v67w) xref: IntAct:EBI-1025857 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018736 name: hba1-hbb-5 direct interaction comment: Deoxy hemoglobin (a-glyglygly-c:v1m,l29w; b,d:v1m) xref: IntAct:EBI-1025867 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018737 name: hba1-hbb-6 direct interaction comment: Deoxy hemoglobin (a,c:v1m,v62l; b,d:v1m,v67l) xref: IntAct:EBI-1025877 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018738 name: hba1-hbb-7 direct interaction comment: Deoxy hemoglobin (a-gly-c:v1m; b,d:v1m,c93a,n108k) xref: IntAct:EBI-1025887 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0018739 name: il1r1-il1rn-1 direct interaction comment: Complex of the interleukin-1 receptor with the interleukin-1 receptor antagonist (il1ra) xref: IntAct:EBI-1026371 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN relationship: has_participant CCO:B0063294 ! IL1RA_HUMAN [Term] id: CCO:I0018740 name: epo-epor-1 direct interaction comment: Erythropoietin complexed with extracellular domains of erythropoietin receptor xref: IntAct:EBI-1027385 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0018741 name: epo-epor-2 direct interaction comment: Crystal structure of human erythropoietin complexed to its receptor at 1.9 angstroms xref: IntAct:EBI-1027396 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0018742 name: pkn1-rhoa-1 direct interaction comment: Crystal structure of human rhoa complexed with the effector domain of the protein kinase pkn/prk1 xref: IntAct:EBI-1028839 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006068 ! PKN1_HUMAN relationship: has_participant CCO:B0020591 ! RHOA_HUMAN [Term] id: CCO:I0018743 name: capn2-capns1-1 direct interaction comment: Crystal structure of human m-calpain form ii xref: IntAct:EBI-1028976 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0041821 ! CAN2_HUMAN [Term] id: CCO:I0018744 name: capn2-capns1-2 direct interaction comment: Crystal structure of human m-calpain form i xref: IntAct:EBI-1028987 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0041821 ! CAN2_HUMAN [Term] id: CCO:I0018745 name: arfip2-rac1-1 direct interaction comment: Crystal structure analysis of rac1-gdp complexed with arfaptin (p21) xref: IntAct:EBI-1031247 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018746 name: arfip2-rac1-2 direct interaction comment: Crystal structure analysis of rac1-gdp in complex with arfaptin (p41) xref: IntAct:EBI-1031258 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018747 name: arfip2-rac1-3 direct interaction comment: Crystal structure analysis of rac1-gmppnp in complex with arfaptin xref: IntAct:EBI-1031269 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN [Term] id: CCO:I0018748 name: fnta-fntb-3 direct interaction comment: Co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound 66 xref: IntAct:EBI-1033558 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:I0018749 name: fnta-fntb-4 direct interaction comment: Co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound 49 xref: IntAct:EBI-1033569 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:I0018750 name: ski-smad4-1 direct interaction comment: Crystal structure of a smad4-ski complex xref: IntAct:EBI-1034780 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0055004 ! SKI_HUMAN [Term] id: CCO:I0018751 name: ar-ncoa4-1 direct interaction comment: Crystal structure of the androgen receptor ligand binding domain (lbd) with dht and a peptide derived from its physiological coactivator ara70 xref: IntAct:EBI-1041177 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0041593 ! NCOA4_HUMAN [Term] id: CCO:I0018752 name: ar-ncoa2-2 direct interaction comment: Crystal structure of the androgen receptor ligand binding domain with dht and a peptide derived from its physiological coactivator grip1 nr box3 xref: IntAct:EBI-1041188 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN [Term] id: CCO:I0018753 name: ar-ncoa2-3 direct interaction comment: Crystal structure of the androgen receptor ligand binding domain with dht and a peptide derived form its physiological coactivator grip1 nr box 2 bound in a non- helical conformation xref: IntAct:EBI-1041199 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN [Term] id: CCO:I0018754 name: abl2-crk-2 phosphorylation comment: Phosphorylation of Crk by Abl2 xref: IntAct:EBI-1102829 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005685 ! ABL2_HUMAN relationship: has_participant CCO:B0055376 ! CRK_HUMAN [Term] id: CCO:I0018755 name: zo_1-cx43 physical interaction xref: IntAct:EBI-1103463 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005330 ! ZO1_HUMAN relationship: has_participant CCO:B0043520 ! CXA1_HUMAN [Term] id: CCO:I0018756 name: fnbp1-tnks-3 physical interaction xref: IntAct:EBI-1111347 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005386 ! FNBP1_HUMAN relationship: has_participant CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:I0018757 name: myst2-ar-1 direct interaction comment: FLAG-tagged human HBO1 (MYST2) coimmunoprecipiates the human androgen receptor xref: IntAct:EBI-1179993 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN [Term] id: CCO:I0018758 name: prkd1-mt2a-2 physical interaction comment: PKCmu kinase domain and C1 domain interact with MT 2A in a beta-galactosidase assay xref: IntAct:EBI-1181125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:I0018759 name: mt2a-prkd1-2 colocalization comment: PKCmu colocalizes with MT 2A in LNCaP cells xref: IntAct:EBI-1181180 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:I0018760 name: cdr2-morf4l2-2 physical interaction comment: PDC17 interacts with MRG X in a yeast two-hybrid assay xref: IntAct:EBI-1181377 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0063018 ! CDR2_HUMAN [Term] id: CCO:I0018761 name: zbtb16-q8iub0 physical interaction comment: PLZF interacts with CCS-3 in a yeast two-hybrid assay xref: IntAct:EBI-1189435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN relationship: has_participant CCO:B0063237 ! Q8IUB0_HUMAN [Term] id: CCO:I0018762 name: tssk4-creb1-2 physical interaction comment: Interaction between TSSK4 and CREB1 identified by Y2H xref: IntAct:EBI-1202618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:I0018763 name: all1-all1-1 direct interaction xref: IntAct:EBI-1203332 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:I0018764 name: xab2-ckn1-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-295281 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041548 ! SYF1_HUMAN relationship: has_participant CCO:B0055887 ! ERCC8_HUMAN [Term] id: CCO:I0018765 name: xab2-ercc6-1 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-295298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0041548 ! SYF1_HUMAN relationship: has_participant CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:I0018766 name: akt1-akt1-1 physical interaction comment: Aggregation of Akt1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-296137 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:I0018767 name: tnfrsf1a-arts1 physical interaction comment: Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding. xref: IntAct:EBI-299464 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0062994 ! ERAP1_HUMAN [Term] id: CCO:I0018768 name: ppl-akt1-2 physical interaction comment: Interaction between PPL and AKT1 confirmed by co-immunoprecipitation xref: IntAct:EBI-368320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0063295 ! PEPL_HUMAN [Term] id: CCO:I0018769 name: abi1-nck1 physical interaction xref: IntAct:EBI-389899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN [Term] id: CCO:I0018770 name: med8-nut2-1 physical interaction comment: interaction detected by CoIP. xref: IntAct:EBI-398492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0018771 name: eea1-rab22a-3 physical interaction comment: In vitro binding of Rab22a to EEA1. xref: IntAct:EBI-399481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005237 ! RB22A_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0018772 name: eea1-rab5a-2 physical interaction comment: In vitro binding of Rab5a to EEA1 xref: IntAct:EBI-399487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0023551 ! RAB5A_HUMAN relationship: has_participant CCO:B0063025 ! EEA1_HUMAN [Term] id: CCO:I0018773 name: irak1-peli2-2 physical interaction comment: Interaction of PELI2 and IRAK1 confirmed by co-ip xref: IntAct:EBI-448418 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0063261 ! PELI2_HUMAN [Term] id: CCO:I0018774 name: irak4-peli2-3 physical interaction comment: Interaction of PELI2 and IRAK4 confirmed by co-ip xref: IntAct:EBI-448432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN relationship: has_participant CCO:B0063261 ! PELI2_HUMAN [Term] id: CCO:I0018775 name: ruvbl2-ruvbl2 physical interaction comment: Dimerization and trimerization of TAP54beta, as detected by filtration chromatography. xref: IntAct:EBI-449155 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN [Term] id: CCO:I0018776 name: sec5-gnefr-1 physical interaction comment: Interaction detected by gst pulldown xref: IntAct:EBI-465724 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059123 ! SRGEF_HUMAN relationship: has_participant CCO:B0063296 ! EXOC2_HUMAN [Term] id: CCO:I0018777 name: hd-git1-7 colocalization comment: Co-localization of endogenous huntingtin with endogenous GIT-1 in PC12 cells xref: IntAct:EBI-472984 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0018778 name: nek3-prlr-1 physical interaction xref: IntAct:EBI-476056 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028319 ! NEK3_HUMAN relationship: has_participant CCO:B0055053 ! PRLR_HUMAN [Term] id: CCO:I0018779 name: nek3-vav2-3 physical interaction xref: IntAct:EBI-476152 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028319 ! NEK3_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN [Term] id: CCO:I0018780 name: vav2-prlr-1 physical interaction xref: IntAct:EBI-476219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055053 ! PRLR_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN [Term] id: CCO:I0018781 name: nek3-vav2-1 physical interaction xref: IntAct:EBI-476292 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028319 ! NEK3_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN [Term] id: CCO:I0018782 name: akt1-akt1-2 physical interaction comment: Aggregation of Akt1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-492734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005512 ! AKT1_HUMAN [Term] id: CCO:I0018783 name: tnfrsf6-fadd-8 physical interaction comment: Interaction between FasLR and FADD demonstrated by co-immunoprecipitation xref: IntAct:EBI-495058 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0018784 name: tnfrsf6-fadd-9 physical interaction comment: Interaction between FasLR and FADD demonstrated by co-immunoprecipitation xref: IntAct:EBI-495070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0018785 name: fadd-exportin-5 physical interaction comment: The fadd protein interacts with the nucleocytoplasmic shuttling protein exportin-5 xref: IntAct:EBI-517945 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037436 ! XPO5_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0018786 name: mbd4-fadd physical interaction comment: The Methyl CpG binding protein 4 interacts with the FADD protein xref: IntAct:EBI-518128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0063002 ! MBD4_HUMAN [Term] id: CCO:I0018787 name: fadd-mbd4-2 physical interaction comment: The FADD protein interacts with the Methyl CpG binding protein 4 xref: IntAct:EBI-518139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0063002 ! MBD4_HUMAN [Term] id: CCO:I0018788 name: birc2-casp7-2 physical interaction comment: Inhibition of caspase activity of caspase 7 by C-IAP1 xref: IntAct:EBI-524056 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0055530 ! CASP7_HUMAN [Term] id: CCO:I0018789 name: birc2-casp3-3 physical interaction comment: Inhibition of caspase activity of caspase 3 by C-IAP1 xref: IntAct:EBI-524076 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0055351 ! CASP3_HUMAN [Term] id: CCO:I0018790 name: birc7-casp3-4 physical interaction comment: Inhibition of caspase activity of caspase 3 by ML-IAP1 xref: IntAct:EBI-524084 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055351 ! CASP3_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN [Term] id: CCO:I0018791 name: ang-actn2-2 physical interaction comment: His-pulled down: bait= human alpha-actinin-2, prey= human angiogenin xref: IntAct:EBI-525326 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN [Term] id: CCO:I0018792 name: xedar-traf6 physical interaction comment: Coimmunoprecipitation reveals interaction between the Tumor necrosis factor receptor superfamily member 27 (XEDAR) protein and the TNF receptor associated factor 6 (TRAF6) protein xref: IntAct:EBI-526063 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0058770 ! TNR27_HUMAN [Term] id: CCO:I0018793 name: xedar-traf3 physical interaction comment: Coimmunoprecipitation reveals interaction between the Tumor necrosis factor receptor superfamily member 27 (XEDAR) protein and the TNF receptor associated factor 3 (TRAF3) protein xref: IntAct:EBI-526089 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0058770 ! TNR27_HUMAN [Term] id: CCO:I0018794 name: xedar-fadd physical interaction comment: Coimmunoprecipitation reveals interaction between the Tumor necrosis factor receptor superfamily member 27 (XEDAR) protein and the FADD protein xref: IntAct:EBI-526124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0058770 ! TNR27_HUMAN [Term] id: CCO:I0018795 name: eif2c1-dicer1-1 physical interaction xref: IntAct:EBI-528294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016057 ! I2C1_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0018796 name: rnase3l-dgcr8-4 physical interaction xref: IntAct:EBI-528508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006026 ! RNC_HUMAN relationship: has_participant CCO:B0058048 ! DGCR8_HUMAN [Term] id: CCO:I0018797 name: tnf_r1-tradd physical interaction comment: Anti-bait coimmunoprecipitation reveals components of the tumor necrosis factor receptor signalling complex xref: IntAct:EBI-528532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0018798 name: ikk-csn3-1 physical interaction comment: Coimmunoprecipitation reveals interaction between the NF-kappa-B essential modulator protein (IKK gamma) and the COP9 signalosome complex subunit 3 protein xref: IntAct:EBI-530750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0018799 name: araf-rabggtb physical interaction comment: Y2H: bait = A-Raf ,prey = RABGGTbeta xref: IntAct:EBI-536908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063297 ! PGTB2_HUMAN [Term] id: CCO:I0018800 name: araf-th1l physical interaction comment: Y2H: bait = A-Raf ,prey = TH1-NELF-C/D xref: IntAct:EBI-536915 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0018801 name: araf-c20orf14 physical interaction comment: Y2H: bait = A-Raf ,prey = TOM-U5 snRNP-associated 102 kDa protein xref: IntAct:EBI-536922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0054708 ! PRP6_HUMAN [Term] id: CCO:I0018802 name: araf-efemp1 physical interaction comment: Y2H: bait = A-Raf ,prey = FBNL-FBL3_HUMAN xref: IntAct:EBI-536929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0005955 ! FBLN3_HUMAN [Term] id: CCO:I0018803 name: araf-rabggtb-1 physical interaction comment: Y2H: bait = A-Raf ,prey = RABGGTbeta xref: IntAct:EBI-536999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063297 ! PGTB2_HUMAN [Term] id: CCO:I0018804 name: araf-c20orf14-2 physical interaction comment: Y2H: bait = A-Raf ,prey = TOM-U5 snRNP-associated 102 kDa protein xref: IntAct:EBI-537006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0054708 ! PRP6_HUMAN [Term] id: CCO:I0018805 name: araf-htim44-1 physical interaction comment: Y2H: bait = A-Raf ,prey = TIMM44 xref: IntAct:EBI-537013 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063251 ! TIM44_HUMAN [Term] id: CCO:I0018806 name: araf-ass-1 physical interaction comment: Y2H: bait = A-Raf ,prey = ASS-hA33M-ASSY_HUMAN xref: IntAct:EBI-537020 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063252 ! ASSY_HUMAN [Term] id: CCO:I0018807 name: araf-th1l-2 physical interaction comment: Y2H: bait = A-Raf ,prey = TH1-NELF-C/D xref: IntAct:EBI-537027 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0018808 name: araf-efemp1-1 physical interaction comment: Y2H: bait = A-Raf ,prey = FBNL-FBL3_HUMAN xref: IntAct:EBI-537034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0005955 ! FBLN3_HUMAN [Term] id: CCO:I0018809 name: araf-pkm2 physical interaction comment: Y2H: bait = A-Raf ,prey = PyK-KPYM_HUMAN xref: IntAct:EBI-537041 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:I0018810 name: araf-nudt14-1 physical interaction comment: Y2H: bait = A-Raf ,prey = hA21-NU14_HUMAN-UGPPase xref: IntAct:EBI-537062 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063253 ! NUD14_HUMAN [Term] id: CCO:I0018811 name: araf-cops3-1 physical interaction comment: Y2H: bait = A-Raf ,prey = SGN3-COP9 complex subunit 3 xref: IntAct:EBI-537069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0018812 name: araf-rras2-1 physical interaction comment: Y2H: bait = A-Raf ,prey = R-RAS xref: IntAct:EBI-537083 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN [Term] id: CCO:I0018813 name: araf-cps1-1 physical interaction comment: Y2H: bait = A-Raf ,prey = CPS1-CPSM_HUMAN xref: IntAct:EBI-537090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:I0018814 name: araf-rabggtb-2 physical interaction comment: Y2H: bait = A-Raf ,prey = RABGGTbeta xref: IntAct:EBI-537097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063297 ! PGTB2_HUMAN [Term] id: CCO:I0018815 name: araf-th1l-3 physical interaction comment: Y2H: bait = A-Raf ,prey = TH1-NELF-C/D xref: IntAct:EBI-537104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0018816 name: araf-c20orf14-3 physical interaction comment: Y2H: bait = A-Raf ,prey = TOM-U5 snRNP-associated 102 kDa protein xref: IntAct:EBI-537111 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0054708 ! PRP6_HUMAN [Term] id: CCO:I0018817 name: araf-htim44-2 physical interaction comment: Y2H: bait = A-Raf ,prey = TIMM44 xref: IntAct:EBI-537118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063251 ! TIM44_HUMAN [Term] id: CCO:I0018818 name: araf-ass-2 physical interaction comment: Y2H: bait = A-Raf ,prey = ASS-hA33M-ASSY_HUMAN xref: IntAct:EBI-537125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063252 ! ASSY_HUMAN [Term] id: CCO:I0018819 name: araf-nudt14-2 physical interaction comment: Y2H: bait = A-Raf ,prey = hA21-NU14_HUMAN-UGPPase xref: IntAct:EBI-537132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063253 ! NUD14_HUMAN [Term] id: CCO:I0018820 name: araf-cops3-2 physical interaction comment: Y2H: bait = A-Raf ,prey = SGN3-COP9 complex subunit 3 xref: IntAct:EBI-537139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0018821 name: araf-rras2-2 physical interaction comment: Y2H: bait = A-Raf ,prey = R-RAS xref: IntAct:EBI-537153 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN [Term] id: CCO:I0018822 name: araf-efemp1-2 physical interaction comment: Y2H: bait = A-Raf ,prey = FBNL-FBL3_HUMAN xref: IntAct:EBI-537167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0005955 ! FBLN3_HUMAN [Term] id: CCO:I0018823 name: araf-cps1-2 physical interaction comment: "Y2H: bait = A-Raf ,prey = CPS1-CPSM_HUMAN" xref: IntAct:EBI-537174 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:I0018824 name: araf-ass-3 physical interaction comment: "Y2H: bait = A-Raf ,prey = ASS-hA33M-ASSY_HUMAN" xref: IntAct:EBI-537181 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0063252 ! ASSY_HUMAN [Term] id: CCO:I0018825 name: cdc42-itsn1-2 physical interaction comment: Intersectin 1 (itsn1) catalyzes nucleotide exchange of cdc42 xref: IntAct:EBI-602112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0018826 name: rhoa-arhgef5-3 physical interaction comment: Tim (ARHGEF5) catalyzes nucleotide exchange of RhoA xref: IntAct:EBI-602212 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0055839 ! ARHG5_HUMAN [Term] id: CCO:I0018827 name: snrpa-sfpq-3 physical interaction xref: IntAct:EBI-607110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0063003 ! SNRPA_HUMAN [Term] id: CCO:I0018828 name: mst4-mst4-2 physical interaction comment: Homodimer formation by Mst4 demonstrated by coimmunoprecipitation xref: IntAct:EBI-618267 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:I0018829 name: mst4-mst4-3 physical interaction comment: Homodimer formation by Mst4 demonstrated by coimmunoprecipitation xref: IntAct:EBI-618279 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:I0018830 name: mst4-golga2-3 colocalization comment: Interaction between Mst4 and GM130 identified by coimmunofluorescence xref: IntAct:EBI-620812 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN relationship: has_participant CCO:B0022753 ! MST4_HUMAN [Term] id: CCO:I0018831 name: sfrs2-1700023b02rik colocalization comment: Nuclear localization of CIR is overlapped wtih that of SR proteins in nuclear speckles. xref: IntAct:EBI-627056 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063030 ! SFRS2_HUMAN [Term] id: CCO:I0018832 name: cir-u2af1-4 direct interaction comment: CIR interacts with u2af1, as detected by anti-GST pull down. xref: IntAct:EBI-632530 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0063031 ! U2AF1_HUMAN [Term] id: CCO:I0018833 name: cir-hdac1-1 colocalization comment: Interaction of CIR and HDAC1, detected by coimmunofluorescence. xref: IntAct:EBI-632665 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN [Term] id: CCO:I0018834 name: rbpsuh-skiip-1 physical interaction comment: SKIP interacts with CBF1 as detected by Y2H. xref: IntAct:EBI-632732 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0048571 ! SNW1_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN [Term] id: CCO:I0018835 name: dmpk-pln-3 phosphorylation comment: Phosphorylation of phospholamban by DMPK xref: IntAct:EBI-692868 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0055804 ! DMPK_HUMAN relationship: has_participant CCO:B0063298 ! PPLA_HUMAN [Term] id: CCO:I0018836 name: dmpk-pln-4 phosphorylation comment: Phosphorylation of phospholamban by DMPK xref: IntAct:EBI-692875 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0055804 ! DMPK_HUMAN relationship: has_participant CCO:B0063298 ! PPLA_HUMAN [Term] id: CCO:I0018837 name: gpiv-fcer1g-1 physical interaction comment: Interaction between BTK and FCER1G demonstrated by coimmunoprecipitation xref: IntAct:EBI-704273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0029424 ! BTK_HUMAN relationship: has_participant CCO:B0055217 ! FCERG_HUMAN [Term] id: CCO:I0018838 name: btk-prkcq-1 physical interaction comment: Interaction between BTK and PRKCQ (PKC-theta) demonstrated by coimmunoprecipitation xref: IntAct:EBI-704294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0018839 name: wrn-vcp-1 physical interaction comment: Pull-down: bait= human WRN, prey= human VCP (AAA ATPase p97) xref: IntAct:EBI-706420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN [Term] id: CCO:I0018840 name: aplp1-znf24-1 physical interaction comment: interaction between APLP1 and ZNF24 detected by anti protein A antibodies COIP xref: IntAct:EBI-707567 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0018841 name: asb13-mark3-1 physical interaction comment: interaction between ASB13 and MARK3 detected by anti protein A antibodies COIP xref: IntAct:EBI-707590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005229 ! MARK3_HUMAN relationship: has_participant CCO:B0058029 ! ASB13_HUMAN [Term] id: CCO:I0018842 name: wrn-fen1-8 physical interaction comment: WRN-holliday junction complex is super-shifted by FEN-1 xref: IntAct:EBI-708337 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0018843 name: wrn-fen1-10 physical interaction comment: WRN interacts directly with FEN-1 as shown by co-immunoprecipitation xref: IntAct:EBI-708423 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0018844 name: golgb1-pfn2-1 physical interaction comment: Interaction between GOLGB1 and PFN2 detected by anti protein A antibodies COIP xref: IntAct:EBI-709985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:I0018845 name: hspca-rps3a-1 physical interaction comment: Interaction between HSPCA and RPS3A detected by anti protein A antibodies COIP xref: IntAct:EBI-710046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN [Term] id: CCO:I0018846 name: polr3f-prpf4b-1 physical interaction comment: Interaction between POLR3F and PRPF4B was detected by Protein A CoIP xref: IntAct:EBI-710079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006101 ! RPC6_HUMAN relationship: has_participant CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:I0018847 name: hspb8-cryab-1 physical interaction comment: Y2h: bait = HSP22 (HSPB8), prey = alpha B crystallin (HSPB5) xref: IntAct:EBI-739088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024107 ! HSPB8_HUMAN relationship: has_participant CCO:B0054861 ! CRYAB_HUMAN [Term] id: CCO:I0018848 name: edf1-nr5a2-1 physical interaction comment: MBF-1 interacts in vitro with LRH-1, as detected by pull-down experiments. xref: IntAct:EBI-781351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054325 ! NR5A2_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0018849 name: edf1-rxra-1 physical interaction comment: MBF-1 interacts in vitro with RXR-alpha as detected by pull down experiments. xref: IntAct:EBI-781426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024886 ! RXRA_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0018850 name: edf1-nr5a2-2 physical interaction comment: The central domain of MBF-1 is necessary and sufficient for interaction with LRH1. xref: IntAct:EBI-781466 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054325 ! NR5A2_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0018851 name: edf1-nr1h3-2 physical interaction comment: The central domain of MBF-1 is necessary and sufficient for interaction with LXR-alpha. xref: IntAct:EBI-781475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054582 ! EDF1_HUMAN relationship: has_participant CCO:B0055878 ! NR1H3_HUMAN [Term] id: CCO:I0018852 name: edf1-pparg-2 physical interaction comment: The central domain of MBF-1 is necessary and sufficient for interaction with PPAR-gamma. xref: IntAct:EBI-781497 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN [Term] id: CCO:I0018853 name: cbx3-trim28-2 physical interaction comment: Interaction detected by GST pull down. xref: IntAct:EBI-78216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0055884 ! CBX3_HUMAN [Term] id: CCO:I0018854 name: cbx5-trim28-1 physical interaction comment: Interaction detected by GST pulldown. xref: IntAct:EBI-78236 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN [Term] id: CCO:I0018855 name: mapk8ip1-app-3 physical interaction comment: mapk8ip1(JIP1)-APP interaction xref: IntAct:EBI-78422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0059280 ! JIP1_HUMAN [Term] id: CCO:I0018856 name: erg-setdb1-2 physical interaction comment: Interaction detected by coimmunoprecipitation. xref: IntAct:EBI-79719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0054991 ! ERG_HUMAN [Term] id: CCO:I0018857 name: erbb4-dlg4-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-80408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:I0018858 name: erbb4-sntb2-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-80423 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0063299 ! SNTB2_HUMAN [Term] id: CCO:I0018859 name: erbb4-dlg2-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-80437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023320 ! DLG2_HUMAN [Term] id: CCO:I0018860 name: erbb4-dlg3-1 physical interaction comment: Interaction detected by Y2H. xref: IntAct:EBI-80454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023306 ! DLG3_HUMAN [Term] id: CCO:I0018861 name: pabp-paip1 3 direct interaction comment: Paip1 interacts with poly(A) binding protein through two independent binding motifs xref: IntAct:EBI-81560 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN [Term] id: CCO:I0018862 name: paip1-pabp 3 direct interaction comment: Paip1 interacts with poly(A) binding protein through two independent binding motifs xref: IntAct:EBI-81564 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN [Term] id: CCO:I0018863 name: tssk6-hspcb-2 physical interaction comment: Interaction of TSSK6 with HSPCB, HSPA8 and HSPA1A identified by coimmunopreciptiation xref: IntAct:EBI-851910 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0063300 ! TSSK6_HUMAN [Term] id: CCO:I0018864 name: polg-polg2-1 direct interaction comment: Interaction of POLG and POLG2 identified by pulldown xref: IntAct:EBI-852658 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:I0018865 name: erbb3-erbb2-1 physical interaction comment: Interaction between human erbB3 and erbB2 detected by coIP xref: IntAct:EBI-875459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN [Term] id: CCO:I0018866 name: erbb3-erbb4-1 physical interaction comment: Interaction between human erbB3 and erbB4 detected by coIP xref: IntAct:EBI-875462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:I0018867 name: erbb4-erbb2-1 physical interaction comment: Interaction between human erbB4 and erbB2 detected by coIP xref: IntAct:EBI-875465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN [Term] id: CCO:I0018868 name: p85a-erbb3-2 physical interaction comment: Interaction between human P85A and erbB3 detected by coIP xref: IntAct:EBI-875568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN [Term] id: CCO:I0018869 name: hdac1-nfkb1 physical interaction xref: IntAct:EBI-904424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0018870 name: hdac1-nfkb1-1 physical interaction xref: IntAct:EBI-904435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN [Term] id: CCO:I0018871 name: hdac1-rela-2 physical interaction xref: IntAct:EBI-904439 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018872 name: hdac1-rela-3 physical interaction xref: IntAct:EBI-904488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0018873 name: grem1-14_3_3 eta physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the Gremlin 1 protein and YWHAH protein xref: IntAct:EBI-914499 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0063191 ! GREM1_HUMAN [Term] id: CCO:I0018874 name: app-nsf-2 physical interaction comment: Interacting partners of human APP from brain samples derived from Alzheimers patients xref: IntAct:EBI-960318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0005541 ! UCHL1_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005699 ! HSP7C_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN relationship: has_participant CCO:B0005775 ! ACTB_HUMAN relationship: has_participant CCO:B0006072 ! PPIA_HUMAN relationship: has_participant CCO:B0006323 ! PGAM1_HUMAN relationship: has_participant CCO:B0006343 ! NFL_HUMAN relationship: has_participant CCO:B0022139 ! DYN1_HUMAN relationship: has_participant CCO:B0038850 ! NSF_HUMAN relationship: has_participant CCO:B0054861 ! CRYAB_HUMAN relationship: has_participant CCO:B0062814 ! GFAP_HUMAN [Term] id: CCO:I0018875 name: ptpn1-actn1-1 dephosphorylation comment: Dephosphorylation of ACTN1 by PTPN1 (PTP 1B) xref: IntAct:EBI-968815 is_a: CCO:Y0000012 ! dephosphorylation reaction relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0055096 ! PTN1_HUMAN [Term] id: CCO:I0018876 name: src-actn1-2 physical interaction comment: Interaction between SRC and ACTN1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-968912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0018877 name: src-fak1-1 physical interaction comment: Interaction between SRC and FAK 1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-968957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005812 ! FAK1_HUMAN [Term] id: CCO:I0018878 name: foxp2-nfatc2-2 physical interaction xref: IntAct:EBI-983799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015717 ! FOXP2_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:I0018879 name: wasl-ptpn2-1 dephosphorylation comment: Dephosphorylation of WASL by PTPN2 xref: IntAct:EBI-984976 is_a: CCO:Y0000012 ! dephosphorylation reaction relationship: has_participant CCO:B0005942 ! WASL_HUMAN relationship: has_participant CCO:B0063302 ! PTN2_HUMAN [Term] id: CCO:I0018880 name: wasl-ptpn2-2 phosphorylation comment: Dephosphorylation of WASL by PTPN2 xref: IntAct:EBI-985019 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0005942 ! WASL_HUMAN relationship: has_participant CCO:B0063302 ! PTN2_HUMAN [Term] id: CCO:I0018881 name: pscd2-atp6v0a2-6 physical interaction comment: Interaction between Pscd2 and Atp6v0a2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-988639 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058410 ! CYH2_HUMAN relationship: has_participant CCO:B0063303 ! VPP2_HUMAN [Term] id: CCO:I0018882 name: arf6-atp6v1c1-2 physical interaction comment: Interaction between Arf6 and Atp6v1c1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-988700 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055616 ! ARF6_HUMAN relationship: has_participant CCO:B0063235 ! VATC1_HUMAN [Term] id: CCO:I0018883 name: gstp1-traf2-3 physical interaction comment: Pulldown assay reveals interaction between GSTP1 and TRAF2 proteins xref: IntAct:EBI-996308 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN [Term] id: CCO:I0018884 name: tmed10-psen1-1 physical interaction xref: IntAct:EBI-998691 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0018885 name: tmed10-ncstn physical interaction xref: IntAct:EBI-998700 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058062 ! NICA_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0018886 name: tmed10-psenen physical interaction xref: IntAct:EBI-998706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058989 ! PEN2_HUMAN relationship: has_participant CCO:B0063015 ! TMEDA_HUMAN [Term] id: CCO:I0018887 name: ubqln4-arl7 physical interaction xref: IntAct:EBI-950104 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0056309 ! Q4A519_HUMAN [Term] id: CCO:I0018888 name: ubqln4-dmpk physical interaction xref: IntAct:EBI-950164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:I0018889 name: ubqln4-gdi1 physical interaction xref: IntAct:EBI-950194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055233 ! GDIA_HUMAN [Term] id: CCO:I0018890 name: ubqln4-hgs physical interaction xref: IntAct:EBI-950206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018891 name: ubqln4-igfbp6 physical interaction xref: IntAct:EBI-950212 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055173 ! IBP6_HUMAN [Term] id: CCO:I0018892 name: ubqln4-moap1 physical interaction xref: IntAct:EBI-950248 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0021834 ! MOAP1_HUMAN [Term] id: CCO:I0018893 name: ubqln4-nme3 physical interaction xref: IntAct:EBI-950260 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005316 ! NDK3_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018894 name: ubqln4-pip5k2b physical interaction xref: IntAct:EBI-950308 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055640 ! PI42B_HUMAN [Term] id: CCO:I0018895 name: ubqln4-prkcabp physical interaction xref: IntAct:EBI-950320 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0018896 name: ubqln4-robo2 physical interaction xref: IntAct:EBI-950356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0058810 ! ROBO2_HUMAN [Term] id: CCO:I0018897 name: ubqln4-scg2 physical interaction xref: IntAct:EBI-950362 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055014 ! SCG2_HUMAN [Term] id: CCO:I0018898 name: ubqln4-tgfb1i1 physical interaction xref: IntAct:EBI-950392 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0017844 ! TGFI1_HUMAN [Term] id: CCO:I0018899 name: ubqln4-traf2 physical interaction xref: IntAct:EBI-950404 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018900 name: ubqln4-zfpm2 physical interaction xref: IntAct:EBI-950452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0057999 ! FOG2_HUMAN [Term] id: CCO:I0018901 name: ubqln4-impdh2 physical interaction xref: IntAct:EBI-950476 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0054998 ! IMDH2_HUMAN [Term] id: CCO:I0018902 name: ubqln4-scg2-1 physical interaction xref: IntAct:EBI-950482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0055014 ! SCG2_HUMAN [Term] id: CCO:I0018903 name: ubqln4-prkcabp-1 physical interaction xref: IntAct:EBI-950488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0018904 name: a2bp1-atxn1-1 physical interaction xref: IntAct:EBI-950500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0018905 name: a2bp1-atxn2 physical interaction xref: IntAct:EBI-950506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0018906 name: a2bp1-lw_1 physical interaction xref: IntAct:EBI-950530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059067 ! HSFX1_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0018907 name: a2bp1-maged1 physical interaction xref: IntAct:EBI-950536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0018908 name: a2bp1-rbm9-1 physical interaction xref: IntAct:EBI-950560 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054463 ! RBM9_HUMAN relationship: has_participant CCO:B0061986 ! FOX1A_HUMAN [Term] id: CCO:I0018909 name: aptx-cep350 physical interaction xref: IntAct:EBI-950620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0063304 ! CE350_HUMAN [Term] id: CCO:I0018910 name: aptx-hivep1 physical interaction xref: IntAct:EBI-950626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0018911 name: aptx-syt17 physical interaction xref: IntAct:EBI-950644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0040086 ! SYT17_HUMAN [Term] id: CCO:I0018912 name: aptx-mbp physical interaction xref: IntAct:EBI-950656 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:I0018913 name: aptx-trim37 physical interaction xref: IntAct:EBI-950662 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005249 ! TRI37_HUMAN relationship: has_participant CCO:B0005943 ! APTX_HUMAN [Term] id: CCO:I0018914 name: aptx-xrcc1 physical interaction xref: IntAct:EBI-950674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:I0018915 name: aptx-znf639 physical interaction xref: IntAct:EBI-950680 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0059156 ! ZN639_HUMAN [Term] id: CCO:I0018916 name: aptx-prkcabp physical interaction xref: IntAct:EBI-950686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0018917 name: aptx-xrcc1-1 physical interaction xref: IntAct:EBI-950698 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0020639 ! XRCC1_HUMAN [Term] id: CCO:I0018918 name: aptx-znf639-1 physical interaction xref: IntAct:EBI-950704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0059156 ! ZN639_HUMAN [Term] id: CCO:I0018919 name: atn1-agrn physical interaction xref: IntAct:EBI-950710 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005949 ! AGRIN_HUMAN [Term] id: CCO:I0018920 name: atn1-cbfa2t2 physical interaction xref: IntAct:EBI-950734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0054482 ! MTG8R_HUMAN [Term] id: CCO:I0018921 name: atn1-cenpj physical interaction xref: IntAct:EBI-950740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005426 ! CENPJ_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0018922 name: atn1-crip2 physical interaction xref: IntAct:EBI-950752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0048868 ! CRIP2_HUMAN [Term] id: CCO:I0018923 name: atn1-dvl2 physical interaction xref: IntAct:EBI-950758 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0018924 name: atn1-ewsr1 physical interaction xref: IntAct:EBI-950788 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005944 ! ATN1_HUMAN [Term] id: CCO:I0018925 name: atn1-grn physical interaction xref: IntAct:EBI-950806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005961 ! GRN_HUMAN [Term] id: CCO:I0018926 name: atn1-kiaa0543 physical interaction xref: IntAct:EBI-950824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0054541 ! ZN862_HUMAN [Term] id: CCO:I0018927 name: atn1-perq1 physical interaction xref: IntAct:EBI-950866 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0054633 ! PERQ1_HUMAN [Term] id: CCO:I0018928 name: atn1-pfkl physical interaction xref: IntAct:EBI-950872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0034104 ! K6PL_HUMAN [Term] id: CCO:I0018929 name: atn1-cbfa2t2-1 physical interaction xref: IntAct:EBI-950908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0054482 ! MTG8R_HUMAN [Term] id: CCO:I0018930 name: atn1-grn-1 physical interaction xref: IntAct:EBI-950992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005961 ! GRN_HUMAN [Term] id: CCO:I0018931 name: atn1-lrp2 physical interaction xref: IntAct:EBI-951010 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0055671 ! LRP2_HUMAN [Term] id: CCO:I0018932 name: atn1-wwp1 physical interaction xref: IntAct:EBI-951064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0058653 ! WWP1_HUMAN [Term] id: CCO:I0018933 name: atn1-aes physical interaction xref: IntAct:EBI-951070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0005987 ! AES_HUMAN [Term] id: CCO:I0018934 name: atn1-arf3 physical interaction xref: IntAct:EBI-951076 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0015284 ! ARF3_HUMAN [Term] id: CCO:I0018935 name: atn1-dmpk physical interaction xref: IntAct:EBI-951106 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:I0018936 name: atn1-ecm1 physical interaction xref: IntAct:EBI-951112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0056158 ! ECM1_HUMAN [Term] id: CCO:I0018937 name: atn1-myst3 physical interaction xref: IntAct:EBI-951166 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:I0018938 name: atn1-myst4 physical interaction xref: IntAct:EBI-951172 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0017931 ! MYST4_HUMAN [Term] id: CCO:I0018939 name: atn1-rbm9 physical interaction xref: IntAct:EBI-951190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0018940 name: atn1-rere physical interaction xref: IntAct:EBI-951196 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0018941 name: atxn1-ubqln4-3 physical interaction xref: IntAct:EBI-951238 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018942 name: atxn1-acaca physical interaction xref: IntAct:EBI-951244 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0035952 ! ACACA_HUMAN [Term] id: CCO:I0018943 name: atxn1-atp1a3 physical interaction xref: IntAct:EBI-951250 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:I0018944 name: atxn1-bat2-1 physical interaction xref: IntAct:EBI-951256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:I0018945 name: atxn1-c20orf102 physical interaction xref: IntAct:EBI-951268 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063305 ! VTM2L_HUMAN [Term] id: CCO:I0018946 name: atxn1-c2orf10 physical interaction xref: IntAct:EBI-951274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063306 ! Z804A_HUMAN [Term] id: CCO:I0018947 name: atxn1-cfl1-1 physical interaction xref: IntAct:EBI-951280 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0018948 name: atxn1-cic physical interaction xref: IntAct:EBI-951286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0018949 name: atxn1-clec4f physical interaction xref: IntAct:EBI-951292 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063307 ! CLC4F_HUMAN [Term] id: CCO:I0018950 name: atxn1-coil physical interaction xref: IntAct:EBI-951298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:I0018951 name: atxn1-fdps physical interaction xref: IntAct:EBI-951304 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063308 ! FPPS_HUMAN [Term] id: CCO:I0018952 name: atxn1-q9h7h0 physical interaction xref: IntAct:EBI-951310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063217 ! M11D1_HUMAN [Term] id: CCO:I0018953 name: atxn1-hivep1-1 physical interaction xref: IntAct:EBI-951316 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0018954 name: atxn1-kiaa0553 physical interaction xref: IntAct:EBI-951322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:I0018955 name: atxn1-klf11 physical interaction xref: IntAct:EBI-951328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054387 ! KLF11_HUMAN [Term] id: CCO:I0018956 name: atxn1-lw_1 physical interaction xref: IntAct:EBI-951334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059067 ! HSFX1_HUMAN [Term] id: CCO:I0018957 name: atxn1-rbm9-1 physical interaction xref: IntAct:EBI-951340 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0018958 name: atxn1-rcn1 physical interaction xref: IntAct:EBI-951346 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063210 ! RCN1_HUMAN [Term] id: CCO:I0018959 name: atxn1-rnf31 physical interaction xref: IntAct:EBI-951352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005982 ! RNF31_HUMAN [Term] id: CCO:I0018960 name: atxn1-yy1ap1-1 physical interaction xref: IntAct:EBI-951358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063012 ! YYAP1_HUMAN [Term] id: CCO:I0018961 name: atxn1-zhx1-1 physical interaction xref: IntAct:EBI-951364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0018962 name: atxn1-znf488 physical interaction xref: IntAct:EBI-951370 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0058291 ! ZN488_HUMAN [Term] id: CCO:I0018963 name: atxn1-ubqln4-4 physical interaction xref: IntAct:EBI-951376 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0018964 name: atxn1-atp1a3-1 physical interaction xref: IntAct:EBI-951382 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055016 ! AT1A3_HUMAN [Term] id: CCO:I0018965 name: atxn1-atxn1-1 physical interaction xref: IntAct:EBI-951388 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0018966 name: atxn1-c20orf102-1 physical interaction xref: IntAct:EBI-951394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063305 ! VTM2L_HUMAN [Term] id: CCO:I0018967 name: atxn1-cfl1-2 physical interaction xref: IntAct:EBI-951400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0018968 name: atxn1-cic-1 physical interaction xref: IntAct:EBI-951406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0018969 name: atxn1-coil-1 physical interaction xref: IntAct:EBI-951412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:I0018970 name: atxn1-dmpk physical interaction xref: IntAct:EBI-951418 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:I0018971 name: atxn1-q96d80 physical interaction xref: IntAct:EBI-951424 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063310 ! Q96D80_HUMAN [Term] id: CCO:I0018972 name: atxn1-q9h7h0-1 physical interaction xref: IntAct:EBI-951430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063217 ! M11D1_HUMAN [Term] id: CCO:I0018973 name: atxn1-gmeb2 physical interaction xref: IntAct:EBI-951436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059191 ! GMEB2_HUMAN [Term] id: CCO:I0018974 name: atxn1-hivep1-2 physical interaction xref: IntAct:EBI-951442 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0018975 name: atxn1-ipo8 physical interaction xref: IntAct:EBI-951448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0050581 ! IPO8_HUMAN [Term] id: CCO:I0018976 name: atxn1-kiaa0553-1 physical interaction xref: IntAct:EBI-951454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:I0018977 name: atxn1-mbp physical interaction xref: IntAct:EBI-951460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0031679 ! MBP_HUMAN [Term] id: CCO:I0018978 name: atxn1-phpt1 physical interaction xref: IntAct:EBI-951466 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062779 ! PHP14_HUMAN [Term] id: CCO:I0018979 name: atxn1-rbm9-2 physical interaction xref: IntAct:EBI-951472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0018980 name: atxn1-rcn1-1 physical interaction xref: IntAct:EBI-951478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063210 ! RCN1_HUMAN [Term] id: CCO:I0018981 name: atxn1-six5-1 physical interaction xref: IntAct:EBI-951484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057426 ! SIX5_HUMAN [Term] id: CCO:I0018982 name: atxn1-srebf1 physical interaction xref: IntAct:EBI-951490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0049929 ! SRBP1_HUMAN [Term] id: CCO:I0018983 name: atxn1-tmem23 physical interaction xref: IntAct:EBI-951496 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063311 ! SMS1_HUMAN [Term] id: CCO:I0018984 name: atxn1-ttc19 physical interaction xref: IntAct:EBI-951502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063312 ! TTC19_HUMAN [Term] id: CCO:I0018985 name: atxn1-yy1ap1-2 physical interaction xref: IntAct:EBI-951508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063012 ! YYAP1_HUMAN [Term] id: CCO:I0018986 name: atxn1-zhx1-2 physical interaction xref: IntAct:EBI-951514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0018987 name: atxn1-znf488-1 physical interaction xref: IntAct:EBI-951520 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0058291 ! ZN488_HUMAN [Term] id: CCO:I0018988 name: atxn1-atxn2-1 physical interaction xref: IntAct:EBI-951532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0018989 name: atxn1-atxn2l physical interaction xref: IntAct:EBI-951538 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:I0018990 name: atxn1-bat2-2 physical interaction xref: IntAct:EBI-951544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:I0018991 name: atxn1-cic-2 physical interaction xref: IntAct:EBI-951550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0018992 name: atxn1-zc3h10 physical interaction xref: IntAct:EBI-951556 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063216 ! ZC3HA_HUMAN [Term] id: CCO:I0018993 name: atxn1-fyn physical interaction xref: IntAct:EBI-951562 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0018994 name: atxn1-hivep1-3 physical interaction xref: IntAct:EBI-951568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0018995 name: atxn1-hpcal1 physical interaction xref: IntAct:EBI-951574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062908 ! HPCL1_HUMAN [Term] id: CCO:I0018996 name: atxn1-hsn2 physical interaction xref: IntAct:EBI-951580 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063314 ! HSN2_HUMAN [Term] id: CCO:I0018997 name: atxn1-kiaa0553-2 physical interaction xref: IntAct:EBI-951598 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:I0018998 name: atxn1-kiaa0685 physical interaction xref: IntAct:EBI-951604 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063315 ! SAPS2_HUMAN [Term] id: CCO:I0018999 name: atxn1-r3hdm2 physical interaction xref: IntAct:EBI-951616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063316 ! R3HD2_HUMAN [Term] id: CCO:I0019000 name: atxn1-klf11-1 physical interaction xref: IntAct:EBI-951622 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054387 ! KLF11_HUMAN [Term] id: CCO:I0019001 name: atxn1-lw_1-1 physical interaction xref: IntAct:EBI-951628 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059067 ! HSFX1_HUMAN [Term] id: CCO:I0019002 name: atxn1-mterfd2 physical interaction xref: IntAct:EBI-951634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063317 ! MTER2_HUMAN [Term] id: CCO:I0019003 name: atxn1-oaz1 physical interaction xref: IntAct:EBI-951640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063318 ! OAZ1_HUMAN [Term] id: CCO:I0019004 name: atxn1-pum1 physical interaction xref: IntAct:EBI-951646 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0024392 ! PUM1_HUMAN [Term] id: CCO:I0019005 name: atxn1-rapgef4 physical interaction xref: IntAct:EBI-951652 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0058055 ! RPGF4_HUMAN [Term] id: CCO:I0019006 name: atxn1-rbm9-3 physical interaction xref: IntAct:EBI-951658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0019007 name: atxn1-rics physical interaction xref: IntAct:EBI-951664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063319 ! Q86UT2_HUMAN [Term] id: CCO:I0019008 name: atxn1-six5-2 physical interaction xref: IntAct:EBI-951670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057426 ! SIX5_HUMAN [Term] id: CCO:I0019009 name: atxn1-spen physical interaction xref: IntAct:EBI-951676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:I0019010 name: atxn1-kiaa0809 physical interaction xref: IntAct:EBI-951682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:I0019011 name: atxn1-ube2e3 physical interaction xref: IntAct:EBI-951688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0043535 ! UB2E3_HUMAN [Term] id: CCO:I0019012 name: atxn1-wnk2 physical interaction xref: IntAct:EBI-951700 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059344 ! WNK2_HUMAN [Term] id: CCO:I0019013 name: atxn1-zfp276 physical interaction xref: IntAct:EBI-951706 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057470 ! ZN276_HUMAN [Term] id: CCO:I0019014 name: atxn1-zhx1-3 physical interaction xref: IntAct:EBI-951712 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019015 name: atxn1-zhx2 physical interaction xref: IntAct:EBI-951718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0022038 ! ZHX2_HUMAN [Term] id: CCO:I0019016 name: atxn1-zhx3 physical interaction xref: IntAct:EBI-951724 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0022040 ! ZHX3_HUMAN [Term] id: CCO:I0019017 name: atxn1-arid5a physical interaction xref: IntAct:EBI-951742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055730 ! ARI5A_HUMAN [Term] id: CCO:I0019018 name: atxn1-atxn1-2 physical interaction xref: IntAct:EBI-951748 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019019 name: atxn1-atxn2-2 physical interaction xref: IntAct:EBI-951754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0019020 name: atxn1-atxn2l-1 physical interaction xref: IntAct:EBI-951760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063313 ! ATX2L_HUMAN [Term] id: CCO:I0019021 name: atxn1-bat2-3 physical interaction xref: IntAct:EBI-951766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005898 ! BAT2_HUMAN [Term] id: CCO:I0019022 name: atxn1-c14orf92 physical interaction xref: IntAct:EBI-951772 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054703 ! TOX4_HUMAN [Term] id: CCO:I0019023 name: atxn1-c20orf102-2 physical interaction xref: IntAct:EBI-951778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063305 ! VTM2L_HUMAN [Term] id: CCO:I0019024 name: atxn1-c2orf10-1 physical interaction xref: IntAct:EBI-951784 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063306 ! Z804A_HUMAN [Term] id: CCO:I0019025 name: atxn1-cic-3 physical interaction xref: IntAct:EBI-951790 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0019026 name: atxn1-cst3 physical interaction xref: IntAct:EBI-951796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063321 ! CYTC_HUMAN [Term] id: CCO:I0019027 name: atxn1-dmpk-1 physical interaction xref: IntAct:EBI-951802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:I0019028 name: atxn1-dnaja3 physical interaction xref: IntAct:EBI-951808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0019029 name: atxn1-dzip3 physical interaction xref: IntAct:EBI-951814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063271 ! DZIP3_HUMAN [Term] id: CCO:I0019030 name: atxn1-efemp2 physical interaction xref: IntAct:EBI-951820 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019031 name: atxn1-eif1ay physical interaction xref: IntAct:EBI-951826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0016435 ! IF1AY_HUMAN [Term] id: CCO:I0019032 name: atxn1-eif4enif1 physical interaction xref: IntAct:EBI-951832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0006012 ! 4ET_HUMAN [Term] id: CCO:I0019033 name: atxn1-entpd6 physical interaction xref: IntAct:EBI-951838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063322 ! ENTP6_HUMAN [Term] id: CCO:I0019034 name: atxn1-fam48a physical interaction xref: IntAct:EBI-951844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063193 ! FA48A_HUMAN [Term] id: CCO:I0019035 name: atxn1-fhl2 physical interaction xref: IntAct:EBI-951850 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005830 ! FHL2_HUMAN [Term] id: CCO:I0019036 name: atxn1-zc3h10-1 physical interaction xref: IntAct:EBI-951856 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063216 ! ZC3HA_HUMAN [Term] id: CCO:I0019037 name: atxn1-q9nxg9 physical interaction xref: IntAct:EBI-951862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063323 ! Q9NXG9_HUMAN [Term] id: CCO:I0019038 name: atxn1-fyn-1 physical interaction xref: IntAct:EBI-951868 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0019039 name: atxn1-g2 physical interaction xref: IntAct:EBI-951874 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063324 ! Q12914_HUMAN [Term] id: CCO:I0019040 name: atxn1-gca physical interaction xref: IntAct:EBI-951880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0026105 ! GRAN_HUMAN [Term] id: CCO:I0019041 name: atxn1-hivep1-4 physical interaction xref: IntAct:EBI-951886 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0019042 name: atxn1-hspa1a physical interaction xref: IntAct:EBI-951892 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN [Term] id: CCO:I0019043 name: atxn1-itgb4 physical interaction xref: IntAct:EBI-951898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0033114 ! ITB4_HUMAN [Term] id: CCO:I0019044 name: atxn1-kcnab2 physical interaction xref: IntAct:EBI-951904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063325 ! KCAB2_HUMAN [Term] id: CCO:I0019045 name: atxn1-kiaa0553-3 physical interaction xref: IntAct:EBI-951916 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063309 ! GPTC8_HUMAN [Term] id: CCO:I0019046 name: atxn1-kiaa0685-1 physical interaction xref: IntAct:EBI-951922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063315 ! SAPS2_HUMAN [Term] id: CCO:I0019047 name: atxn1-r3hdm2-1 physical interaction xref: IntAct:EBI-951934 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063316 ! R3HD2_HUMAN [Term] id: CCO:I0019048 name: atxn1-lw_1-2 physical interaction xref: IntAct:EBI-951946 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059067 ! HSFX1_HUMAN [Term] id: CCO:I0019049 name: atxn1-mll4 physical interaction xref: IntAct:EBI-951958 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0043865 ! MLL4_HUMAN [Term] id: CCO:I0019050 name: atxn1-myst3 physical interaction xref: IntAct:EBI-951964 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0017927 ! MYST3_HUMAN [Term] id: CCO:I0019051 name: atxn1-ncor1 physical interaction xref: IntAct:EBI-951976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054626 ! NCOR1_HUMAN [Term] id: CCO:I0019052 name: atxn1-nlk physical interaction xref: IntAct:EBI-951982 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN [Term] id: CCO:I0019053 name: atxn1-nr4a1 physical interaction xref: IntAct:EBI-951988 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0055150 ! NR4A1_HUMAN [Term] id: CCO:I0019054 name: atxn1-pepd physical interaction xref: IntAct:EBI-951994 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0036047 ! PEPD_HUMAN [Term] id: CCO:I0019055 name: atxn1-prdm1 physical interaction xref: IntAct:EBI-952006 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054658 ! PRDM1_HUMAN [Term] id: CCO:I0019056 name: atxn1-r3hdm physical interaction xref: IntAct:EBI-952012 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063326 ! Q4ZG59_HUMAN [Term] id: CCO:I0019057 name: atxn1-rbm9-4 physical interaction xref: IntAct:EBI-952018 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0019058 name: atxn1-rics-1 physical interaction xref: IntAct:EBI-952024 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063319 ! Q86UT2_HUMAN [Term] id: CCO:I0019059 name: atxn1-six5-3 physical interaction xref: IntAct:EBI-952030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057426 ! SIX5_HUMAN [Term] id: CCO:I0019060 name: atxn1-spen-1 physical interaction xref: IntAct:EBI-952036 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0006042 ! MINT_HUMAN [Term] id: CCO:I0019061 name: atxn1-srebf1-1 physical interaction xref: IntAct:EBI-952042 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0049929 ! SRBP1_HUMAN [Term] id: CCO:I0019062 name: atxn1-kiaa0809-1 physical interaction xref: IntAct:EBI-952048 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063320 ! ARIP4_HUMAN [Term] id: CCO:I0019063 name: atxn1-stac2 physical interaction xref: IntAct:EBI-952054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0056992 ! STAC2_HUMAN [Term] id: CCO:I0019064 name: atxn1-tollip physical interaction xref: IntAct:EBI-952060 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019065 name: atxn1-trip6 physical interaction xref: IntAct:EBI-952066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN [Term] id: CCO:I0019066 name: atxn1-ubap2l physical interaction xref: IntAct:EBI-952072 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063327 ! UBP2L_HUMAN [Term] id: CCO:I0019067 name: atxn1-vsnl1 physical interaction xref: IntAct:EBI-952090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005986 ! VISL1_HUMAN [Term] id: CCO:I0019068 name: atxn1-yy1ap1-3 physical interaction xref: IntAct:EBI-952096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063012 ! YYAP1_HUMAN [Term] id: CCO:I0019069 name: atxn1-zhx1-4 physical interaction xref: IntAct:EBI-952102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019070 name: atxn1-zhx3-1 physical interaction xref: IntAct:EBI-952108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0022040 ! ZHX3_HUMAN [Term] id: CCO:I0019071 name: atxn1-zyx physical interaction xref: IntAct:EBI-952114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN [Term] id: CCO:I0019072 name: atxn1-cfl1-3 physical interaction xref: IntAct:EBI-952120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0019073 name: atxn1-cirbp physical interaction xref: IntAct:EBI-952126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0032462 ! CIRBP_HUMAN [Term] id: CCO:I0019074 name: atxn1-rp1_159a19_1 physical interaction xref: IntAct:EBI-952132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:I0019075 name: atxn1-q96d80-1 physical interaction xref: IntAct:EBI-952138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063310 ! Q96D80_HUMAN [Term] id: CCO:I0019076 name: atxn1-q9h7h0-2 physical interaction xref: IntAct:EBI-952144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063217 ! M11D1_HUMAN [Term] id: CCO:I0019077 name: atxn1-gmeb2-1 physical interaction xref: IntAct:EBI-952150 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0059191 ! GMEB2_HUMAN [Term] id: CCO:I0019078 name: atxn1-ipo8-1 physical interaction xref: IntAct:EBI-952156 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0050581 ! IPO8_HUMAN [Term] id: CCO:I0019079 name: atxn1-ptgds physical interaction xref: IntAct:EBI-952162 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063329 ! PTGDS_HUMAN [Term] id: CCO:I0019080 name: atxn1-rcn1-2 physical interaction xref: IntAct:EBI-952168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063210 ! RCN1_HUMAN [Term] id: CCO:I0019081 name: atxn1-zc3h7b physical interaction xref: IntAct:EBI-952174 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0029451 ! Z3H7B_HUMAN [Term] id: CCO:I0019082 name: atxn1-znf609 physical interaction xref: IntAct:EBI-952180 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063330 ! ZN609_HUMAN [Term] id: CCO:I0019083 name: atxn1-ubqln4-5 physical interaction xref: IntAct:EBI-952186 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN [Term] id: CCO:I0019084 name: atxn1-adcy6 physical interaction xref: IntAct:EBI-952192 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0054469 ! ADCY6_HUMAN [Term] id: CCO:I0019085 name: atxn1-acot7 physical interaction xref: IntAct:EBI-952198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0033823 ! BACH_HUMAN [Term] id: CCO:I0019086 name: atxn1-cfl1-4 physical interaction xref: IntAct:EBI-952210 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0019087 name: atxn1-clec4f-1 physical interaction xref: IntAct:EBI-952216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063307 ! CLC4F_HUMAN [Term] id: CCO:I0019088 name: atxn1-coil-2 physical interaction xref: IntAct:EBI-952222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005621 ! P80C_HUMAN [Term] id: CCO:I0019089 name: atxn1-derp6-1 physical interaction xref: IntAct:EBI-952234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057948 ! DERP6_HUMAN [Term] id: CCO:I0019090 name: atxn1-rp1_159a19_1-1 physical interaction xref: IntAct:EBI-952240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063328 ! AHDC1_HUMAN [Term] id: CCO:I0019091 name: atxn1-fam21c physical interaction xref: IntAct:EBI-952246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0029890 ! FA21C_HUMAN [Term] id: CCO:I0019092 name: atxn1-flj10404 physical interaction xref: IntAct:EBI-952258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0017183 ! Q6IPW0_HUMAN [Term] id: CCO:I0019093 name: atxn1-q96d80-2 physical interaction xref: IntAct:EBI-952264 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063310 ! Q96D80_HUMAN [Term] id: CCO:I0019094 name: atxn1-q9h7h0-3 physical interaction xref: IntAct:EBI-952270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063217 ! M11D1_HUMAN [Term] id: CCO:I0019095 name: atxn1-klhl8 physical interaction xref: IntAct:EBI-952282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063331 ! KLHL8_HUMAN [Term] id: CCO:I0019096 name: atxn1-ldb1 physical interaction xref: IntAct:EBI-952288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0057244 ! LDB1_HUMAN [Term] id: CCO:I0019097 name: atxn1-lrsam1 physical interaction xref: IntAct:EBI-952294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0006335 ! LRSM1_HUMAN [Term] id: CCO:I0019098 name: atxn1-matn2 physical interaction xref: IntAct:EBI-952300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0030003 ! MATN2_HUMAN [Term] id: CCO:I0019099 name: atxn1-myo18a physical interaction xref: IntAct:EBI-952306 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0058072 ! MY18A_HUMAN [Term] id: CCO:I0019100 name: atxn1-nars physical interaction xref: IntAct:EBI-952312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063332 ! SYNC_HUMAN [Term] id: CCO:I0019101 name: atxn1-phpt1-1 physical interaction xref: IntAct:EBI-952318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0062779 ! PHP14_HUMAN [Term] id: CCO:I0019102 name: atxn1-ptgds-1 physical interaction xref: IntAct:EBI-952330 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063329 ! PTGDS_HUMAN [Term] id: CCO:I0019103 name: atxn1-sara1 physical interaction xref: IntAct:EBI-952336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063333 ! Q5SQU0_HUMAN [Term] id: CCO:I0019104 name: atxn1-sc4mol physical interaction xref: IntAct:EBI-952342 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063334 ! ERG25_HUMAN [Term] id: CCO:I0019105 name: atxn1-sfrs14 physical interaction xref: IntAct:EBI-952348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063335 ! SFR14_HUMAN [Term] id: CCO:I0019106 name: atxn1-smarcc2 physical interaction xref: IntAct:EBI-952354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019107 name: atxn1-st6galnac6 physical interaction xref: IntAct:EBI-952360 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063336 ! SIA7F_HUMAN [Term] id: CCO:I0019108 name: atxn1-u2af2-1 physical interaction xref: IntAct:EBI-952366 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063011 ! U2AF2_HUMAN [Term] id: CCO:I0019109 name: atxn1-zc3h5 physical interaction xref: IntAct:EBI-952372 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0025523 ! UNK_HUMAN [Term] id: CCO:I0019110 name: atxn1-znf488-2 physical interaction xref: IntAct:EBI-952378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0058291 ! ZN488_HUMAN [Term] id: CCO:I0019111 name: atxn2-actn1 physical interaction xref: IntAct:EBI-952384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0019112 name: atxn2-actn2 physical interaction xref: IntAct:EBI-952390 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0019113 name: atxn2-flj35171 physical interaction xref: IntAct:EBI-952396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0063337 ! Q8NAK8_HUMAN [Term] id: CCO:I0019114 name: atxn2-kiaa1279 physical interaction xref: IntAct:EBI-952402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0043863 ! KBP_HUMAN [Term] id: CCO:I0019115 name: atxn2-sh3gl3 physical interaction xref: IntAct:EBI-952408 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0019116 name: atxn2-tdrd7 physical interaction xref: IntAct:EBI-952414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005496 ! TDRD7_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0019117 name: atxn2-actn1-1 physical interaction xref: IntAct:EBI-952420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0019118 name: atxn2-actn2-1 physical interaction xref: IntAct:EBI-952426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0019119 name: atxn2-bat3 physical interaction xref: IntAct:EBI-952432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:I0019120 name: atxn2-kiaa1279-1 physical interaction xref: IntAct:EBI-952438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0043863 ! KBP_HUMAN [Term] id: CCO:I0019121 name: atxn2-sh3gl2 physical interaction xref: IntAct:EBI-952444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0019122 name: atxn2-sh3gl3-1 physical interaction xref: IntAct:EBI-952450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0019123 name: atxn3-prkcabp physical interaction xref: IntAct:EBI-952456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0049689 ! ATX3_HUMAN [Term] id: CCO:I0019124 name: atxn7-prkcabp physical interaction xref: IntAct:EBI-952462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005945 ! ATX7_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0019125 name: atxn7-rad23a physical interaction xref: IntAct:EBI-952474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005945 ! ATX7_HUMAN relationship: has_participant CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:I0019126 name: atxn7l2-cbx3 physical interaction xref: IntAct:EBI-952480 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055884 ! CBX3_HUMAN relationship: has_participant CCO:B0063221 ! AT7L2_HUMAN [Term] id: CCO:I0019127 name: atxn7l2-lamb1 physical interaction xref: IntAct:EBI-952486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005967 ! LAMB1_HUMAN relationship: has_participant CCO:B0063221 ! AT7L2_HUMAN [Term] id: CCO:I0019128 name: atxn7l3-prkcabp physical interaction xref: IntAct:EBI-952498 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005946 ! Q8IY68_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0019129 name: cic-atxn1 physical interaction xref: IntAct:EBI-952510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0019130 name: cic-cenpj physical interaction xref: IntAct:EBI-952528 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005426 ! CENPJ_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0019131 name: cic-prkcabp physical interaction xref: IntAct:EBI-952534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0063013 ! CIC_HUMAN [Term] id: CCO:I0019132 name: coil-actn1 physical interaction xref: IntAct:EBI-952546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0019133 name: coil-actn2 physical interaction xref: IntAct:EBI-952552 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0019134 name: coil-csnk2b physical interaction xref: IntAct:EBI-952582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN [Term] id: CCO:I0019135 name: coil-ncoa6ip physical interaction xref: IntAct:EBI-952618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:I0019136 name: coil-plekhg4 physical interaction xref: IntAct:EBI-952624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0056375 ! PKHG4_HUMAN [Term] id: CCO:I0019137 name: coil-prkcabp physical interaction xref: IntAct:EBI-952630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0019138 name: coil-snx6 physical interaction xref: IntAct:EBI-952654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0026583 ! SNX6_HUMAN [Term] id: CCO:I0019139 name: coil-tfcp2 physical interaction xref: IntAct:EBI-952660 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0055842 ! TFCP2_HUMAN [Term] id: CCO:I0019140 name: coil-znf277 physical interaction xref: IntAct:EBI-952672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0051775 ! ZN277_HUMAN [Term] id: CCO:I0019141 name: coil-prkcabp-1 physical interaction xref: IntAct:EBI-952684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0019142 name: coil-actn1-1 physical interaction xref: IntAct:EBI-952690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN [Term] id: CCO:I0019143 name: coil-actn2-1 physical interaction xref: IntAct:EBI-952696 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0019144 name: coil-ncoa6ip-1 physical interaction xref: IntAct:EBI-952738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0032700 ! TGS1_HUMAN [Term] id: CCO:I0019145 name: coil-prkcabp-2 physical interaction xref: IntAct:EBI-952750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005621 ! P80C_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0019146 name: fxn-actn1 physical interaction xref: IntAct:EBI-952762 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0032300 ! FRDA_HUMAN [Term] id: CCO:I0019147 name: fxn-prkcabp physical interaction xref: IntAct:EBI-952768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0032300 ! FRDA_HUMAN [Term] id: CCO:I0019148 name: anp32a-kpna1 physical interaction xref: IntAct:EBI-953218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006073 ! AN32A_HUMAN relationship: has_participant CCO:B0020532 ! IMA1_HUMAN [Term] id: CCO:I0019149 name: anp32a-kpna5 physical interaction xref: IntAct:EBI-953224 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005697 ! IMA5_HUMAN relationship: has_participant CCO:B0006073 ! AN32A_HUMAN [Term] id: CCO:I0019150 name: anp32a-kpna6 physical interaction xref: IntAct:EBI-953230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006073 ! AN32A_HUMAN relationship: has_participant CCO:B0020529 ! IMA7_HUMAN [Term] id: CCO:I0019151 name: pcbp1-tsc22d4-1 physical interaction xref: IntAct:EBI-953284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:I0019152 name: pcbp1-hnrpk physical interaction xref: IntAct:EBI-953302 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0028774 ! PCBP1_HUMAN [Term] id: CCO:I0019153 name: prkcg-prkcabp physical interaction xref: IntAct:EBI-953356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:I0019154 name: prkcg-prkcabp-1 physical interaction xref: IntAct:EBI-953362 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0025044 ! KPCG_HUMAN [Term] id: CCO:I0019155 name: prkcg-exoc5 physical interaction xref: IntAct:EBI-953374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025044 ! KPCG_HUMAN relationship: has_participant CCO:B0036875 ! EXOC5_HUMAN [Term] id: CCO:I0019156 name: prkcg-cchcr1 physical interaction xref: IntAct:EBI-953380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025044 ! KPCG_HUMAN relationship: has_participant CCO:B0050075 ! CCHCR_HUMAN [Term] id: CCO:I0019157 name: rere-atn1 physical interaction xref: IntAct:EBI-953398 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019158 name: rere-cbfa2t2 physical interaction xref: IntAct:EBI-953404 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043437 ! RERE_HUMAN relationship: has_participant CCO:B0054482 ! MTG8R_HUMAN [Term] id: CCO:I0019159 name: rere-efemp2 physical interaction xref: IntAct:EBI-953410 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019160 name: rere-prkcbp1 physical interaction xref: IntAct:EBI-953416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005935 ! PKCB1_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019161 name: rere-atn1-1 physical interaction xref: IntAct:EBI-953428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005944 ! ATN1_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019162 name: rere-bat2 physical interaction xref: IntAct:EBI-953434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005898 ! BAT2_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019163 name: rere-cxorf45 physical interaction xref: IntAct:EBI-953440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043437 ! RERE_HUMAN relationship: has_participant CCO:B0063338 ! CX045_HUMAN [Term] id: CCO:I0019164 name: rere-ecm1 physical interaction xref: IntAct:EBI-953446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043437 ! RERE_HUMAN relationship: has_participant CCO:B0056158 ! ECM1_HUMAN [Term] id: CCO:I0019165 name: rere-efemp1 physical interaction xref: IntAct:EBI-953452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005955 ! FBLN3_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019166 name: rere-efemp2-1 physical interaction xref: IntAct:EBI-953458 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019167 name: rere-myst3 physical interaction xref: IntAct:EBI-953470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017927 ! MYST3_HUMAN relationship: has_participant CCO:B0043437 ! RERE_HUMAN [Term] id: CCO:I0019168 name: rere-rbm9 physical interaction xref: IntAct:EBI-953482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043437 ! RERE_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN [Term] id: CCO:I0019169 name: sacs-prkcabp physical interaction xref: IntAct:EBI-953494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0005994 ! SACS_HUMAN [Term] id: CCO:I0019170 name: tbp-brf1 physical interaction xref: IntAct:EBI-953500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0050546 ! TF3B_HUMAN [Term] id: CCO:I0019171 name: tbp-cxxc1 physical interaction xref: IntAct:EBI-953506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0059034 ! CXXC1_HUMAN [Term] id: CCO:I0019172 name: tbp-emid2 physical interaction xref: IntAct:EBI-953512 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0063339 ! EMID2_HUMAN [Term] id: CCO:I0019173 name: tbp-hap1 physical interaction xref: IntAct:EBI-953518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0006153 ! HAP1_HUMAN [Term] id: CCO:I0019174 name: usp7-arnt2 physical interaction xref: IntAct:EBI-953530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005429 ! UBP7_HUMAN relationship: has_participant CCO:B0006033 ! ARNT2_HUMAN [Term] id: CCO:I0019175 name: usp7-dnaja3 physical interaction xref: IntAct:EBI-953548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005429 ! UBP7_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN [Term] id: CCO:I0019176 name: usp7-ewsr1 physical interaction xref: IntAct:EBI-953554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005429 ! UBP7_HUMAN [Term] id: CCO:I0019177 name: usp7-prkcabp physical interaction xref: IntAct:EBI-953614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005429 ! UBP7_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:I0019178 name: usp7-tmpo physical interaction xref: IntAct:EBI-953638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005429 ! UBP7_HUMAN relationship: has_participant CCO:B0055348 ! LAP2A_HUMAN [Term] id: CCO:I0019179 name: usp7-bcor physical interaction xref: IntAct:EBI-953656 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005429 ! UBP7_HUMAN relationship: has_participant CCO:B0056966 ! BCOR_HUMAN [Term] id: CCO:I0019180 name: adamts13-vwf-1 protein cleavage xref: IntAct:EBI-1007861 is_a: CCO:Y0000039 ! protein cleavage relationship: has_participant CCO:B0031878 ! VWF_HUMAN relationship: has_participant CCO:B0057108 ! ATS13_HUMAN [Term] id: CCO:I0019181 name: arhgap1-cdc42-1 direct interaction comment: Complex between cdc42hs.gmppnp and p50 rhogap (h. sapiens) xref: IntAct:EBI-1026599 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN [Term] id: CCO:I0019182 name: gh1-ghr-3 direct interaction comment: Structural plasticity at the hgh:hghbp interface xref: IntAct:EBI-1026633 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054843 ! SOMA_HUMAN relationship: has_participant CCO:B0063273 ! GHR_HUMAN [Term] id: CCO:I0019183 name: ha-hla_dra-1 physical interaction comment: Crystal structure of a complex of a human alpha-beta-t cell receptor, influenza ha antigen peptide, and mhc class ii molecule, hla-dr4 xref: IntAct:EBI-1033150 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0049305 ! TVA3_HUMAN relationship: has_participant CCO:B0055019 ! 2B14_HUMAN relationship: has_participant CCO:B0063340 ! 2DRA_HUMAN relationship: has_participant CCO:B0063341 ! Q8N2T6_HUMAN [Term] id: CCO:I0019184 name: ahsp-hba1-1 direct interaction comment: Crystal structure of ahsp bound to fe(ii) alpha-hemoglobin xref: IntAct:EBI-1041092 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0058994 ! AHSP_HUMAN [Term] id: CCO:I0019185 name: cebpb-smad4 physical interaction xref: IntAct:EBI-1103038 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN [Term] id: CCO:I0019186 name: s100a1-s100p-2 physical interaction xref: IntAct:EBI-1110925 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055155 ! S10A1_HUMAN relationship: has_participant CCO:B0062804 ! S100P_HUMAN [Term] id: CCO:I0019187 name: s100a1-s100p-7 physical interaction xref: IntAct:EBI-1149999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055155 ! S10A1_HUMAN relationship: has_participant CCO:B0062804 ! S100P_HUMAN [Term] id: CCO:I0019188 name: map2k2-araf-2 physical interaction comment: Interaction between MAP2K2 and ARAF identified by Y2H xref: IntAct:EBI-1165021 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:I0019189 name: map2k2-araf-3 direct interaction comment: Interaction between MAP2K2 and ARAF identified by GST pulldown xref: IntAct:EBI-1165031 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN [Term] id: CCO:I0019190 name: atp12-f1alpha-1 direct interaction comment: Interaction between human ATP12 and ATPase F1 alpha subunit detected by Y2H xref: IntAct:EBI-1166937 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005778 ! ATPA_HUMAN relationship: has_participant CCO:B0063342 ! ATPF2_HUMAN [Term] id: CCO:I0019191 name: htatip-atxn1 physical interaction comment: ATXN1 coimmunoprecipitated with Tip60 xref: IntAct:EBI-1170120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019192 name: atxn1-htatip-1 physical interaction comment: ATXN1 coimmunoprecipitated with Tip60 xref: IntAct:EBI-1170157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN [Term] id: CCO:I0019193 name: lass2-asgr1 physical interaction comment: A yeast two hybrid assay indicates LASS2 interacts with AGPRH1 xref: IntAct:EBI-1172345 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019141 ! ASGR1_HUMAN relationship: has_participant CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:I0019194 name: lass2-asgr2 physical interaction comment: A yeast two hybrid assay indicates LASS2 interacts with AGPRH2 xref: IntAct:EBI-1172695 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019143 ! ASGR2_HUMAN relationship: has_participant CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:I0019195 name: lass2-atp6v0c physical interaction comment: A yeast two hybrid assay indicates LASS2 interacts with VPL xref: IntAct:EBI-1172735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028140 ! VATL_HUMAN relationship: has_participant CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:I0019196 name: 12dt1-wdr5 physical interaction xref: IntAct:EBI-1176605 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005615 ! WDR5_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN [Term] id: CCO:I0019197 name: spta1-sptb2-2 direct interaction comment: Interaction between SPTA1 and SPTB2 identified by SPR xref: IntAct:EBI-1178851 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0063212 ! SPTA1_HUMAN [Term] id: CCO:I0019198 name: spta1-sptb2-3 direct interaction comment: Interaction between SPTA1 and SPTB2 identified by SPR xref: IntAct:EBI-1178906 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0063212 ! SPTA1_HUMAN [Term] id: CCO:I0019199 name: spta1-sptb1-1 direct interaction comment: Interaction between SPTA1 and SPTB1 identified by SPR xref: IntAct:EBI-1178954 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054990 ! SPTB1_HUMAN relationship: has_participant CCO:B0063212 ! SPTA1_HUMAN [Term] id: CCO:I0019200 name: spta2-sptb1-2 direct interaction comment: Interaction between SPTA2 and SPTB1 identified by SPR xref: IntAct:EBI-1179890 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054990 ! SPTB1_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019201 name: spta2-sptb1-3 direct interaction comment: Interaction between SPTA2 and SPTB1 identified by SPR xref: IntAct:EBI-1179933 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019202 name: spta2-sptb2-2 direct interaction comment: Interaction between SPTA1 and SPTB2 at 25C identified by SPR xref: IntAct:EBI-1179954 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019203 name: spta2-sptb2-3 direct interaction comment: Interaction between SPTA1 and SPTB2 at 27C identified by SPR xref: IntAct:EBI-1180142 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019204 name: spta2-sptb2-4 direct interaction comment: Interaction between SPTA1 and SPTB2 at 29C identified by SPR xref: IntAct:EBI-1180159 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019205 name: spta2-sptb2-5 direct interaction comment: Interaction between SPTA1 and SPTB2 at 31C identified by SPR xref: IntAct:EBI-1180176 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019206 name: spta2-sptb2-6 direct interaction comment: Interaction between SPTA1 and SPTB2 at 33C identified by SPR xref: IntAct:EBI-1180193 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019207 name: spta2-sptb2-7 direct interaction comment: Interaction between SPTA1 and SPTB2 at 35C identified by SPR xref: IntAct:EBI-1180210 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019208 name: prkd1-mt2a physical interaction comment: PKCmu interacts with MT 2A in a yeast two hybrid assay xref: IntAct:EBI-1181095 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:I0019209 name: prkd1-mt2a-1 physical interaction comment: PKCmu kinase domain and C1 domain interact with MT 2A in a yeast two hybrid assay xref: IntAct:EBI-1181106 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:I0019210 name: mt2a-prkd1-3 colocalization comment: PKCmu colocalizes with MT 2A in C4-2 cells xref: IntAct:EBI-1181193 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0063240 ! KPCD1_HUMAN [Term] id: CCO:I0019211 name: fyn-htr6-1 physical interaction comment: Interaction between HTR6 and FYN identified by Y2H xref: IntAct:EBI-1182221 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN [Term] id: CCO:I0019212 name: tssk4-creb1-1 physical interaction comment: Interaction between TSSK4 and CREB1 identified by Y2H xref: IntAct:EBI-1202599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:I0019213 name: tssk4-creb1-3 physical interaction comment: Interaction between TSSK4 and CREB1 identified by GST pulldown xref: IntAct:EBI-1202633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:I0019214 name: tssk4-creb1-4 phosphorylation comment: Phosphorylation of CREB1 by TSSK4 xref: IntAct:EBI-1202650 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:I0019215 name: 4ebp1-eif4e physical interaction comment: The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins xref: IntAct:EBI-296544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:I0019216 name: sos2-grb2-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-298225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN [Term] id: CCO:I0019217 name: sos2-pacsin3-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-298229 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005666 ! SOS2_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0019218 name: sos2-snx9-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-298233 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005559 ! SNX9_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN [Term] id: CCO:I0019219 name: sos1-grb2-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-298237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN [Term] id: CCO:I0019220 name: sos1-pacsin3-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-298241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:I0019221 name: sos1-snx9-2 physical interaction comment: Interaction detected by CoIP. xref: IntAct:EBI-298245 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005559 ! SNX9_HUMAN [Term] id: CCO:I0019222 name: wrn-xrcc5-1 physical interaction comment: Flag pull-down: bait= WRN K577M, preys= Ku70, ku80, PARP-1 xref: IntAct:EBI-368090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0019223 name: app-apba1-1 physical interaction comment: in vitro co-ip of beta-APP cytoplasmic domain and X11 Phosphotyrosine domain. xref: IntAct:EBI-368901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063022 ! APBA1_HUMAN [Term] id: CCO:I0019224 name: apba1-app-1 physical interaction comment: in vitro co-ip of beta-APP cytoplasmic domain and X11. xref: IntAct:EBI-371441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0063022 ! APBA1_HUMAN [Term] id: CCO:I0019225 name: prkcq-txnl2-1 physical interaction comment: Interaction of PKCtheta and TXNL2 identified by Y2H xref: IntAct:EBI-374792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0062932 ! GLRX3_HUMAN [Term] id: CCO:I0019226 name: abi1-spta1-1 physical interaction xref: IntAct:EBI-375650 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0063212 ! SPTA1_HUMAN [Term] id: CCO:I0019227 name: abi1-ncf3-3 physical interaction comment: co-IP: bait= p47 phox; prey= ABI-1 xref: IntAct:EBI-395177 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0062973 ! NCF1_HUMAN [Term] id: CCO:I0019228 name: surf5-crsp6-1 physical interaction comment: interaction detected by GST-pulldown xref: IntAct:EBI-398745 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN [Term] id: CCO:I0019229 name: surf5-crsp8-1 physical interaction comment: interaction detected by GST-pulldown xref: IntAct:EBI-398751 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN [Term] id: CCO:I0019230 name: surf5-q9p086-1 physical interaction comment: interaction detected by GST-pulldown xref: IntAct:EBI-398757 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN [Term] id: CCO:I0019231 name: robo1-robo2 physical interaction comment: Robo1 and Robo2 interaction detected by in vitro Covasphere aggregation assay. xref: IntAct:EBI-399826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058810 ! ROBO2_HUMAN relationship: has_participant CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:I0019232 name: traf7-map3k3-1 physical interaction comment: Interaction between TRAF7 and MEKK3 demonstrated by coimmunoprecipitation xref: IntAct:EBI-446127 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0056926 ! TRAF7_HUMAN [Term] id: CCO:I0019233 name: irak4-peli2-1 physical interaction comment: Interacting partners of IRAK4 identified by Y2H xref: IntAct:EBI-448406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN relationship: has_participant CCO:B0063261 ! PELI2_HUMAN [Term] id: CCO:I0019234 name: rac1-dock1-1 physical interaction comment: Interaction detected by GST pulled down, bait = human dock 180, prey =human Elmo1 xref: IntAct:EBI-448716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0019235 name: rac1-dock1-2 physical interaction comment: Interaction detected by GST pulled down, bait = human Rac1, prey =human Dock 180 xref: IntAct:EBI-448723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0019236 name: cdc42-was-1 physical interaction comment: fluorescence titration : human cdc42 and human WASP xref: IntAct:EBI-457532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0019237 name: cdc42-was-3 physical interaction comment: circular dichroism : human cdc42 and human WASP xref: IntAct:EBI-457542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0019238 name: rac1-dock1-5 physical interaction comment: Interaction detected by GST pulled down, bait = human dock 180, prey =human Elmo1 xref: IntAct:EBI-457738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0019239 name: rac1-dock1-6 physical interaction comment: Interaction detected by GST pulled down, bait = human Rac1, prey =human Dock 180 xref: IntAct:EBI-457747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN [Term] id: CCO:I0019240 name: hd-git1-4 physical interaction comment: CoIP in cos-1 cells : bait = GIT-1 C terminus fragment , prey= huntingtin Q68 xref: IntAct:EBI-472950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN [Term] id: CCO:I0019241 name: rfc2-prkar1a-3 physical interaction xref: IntAct:EBI-476482 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0019242 name: rela-dhx9-1 physical interaction comment: Interaction of RELA and DHX9 demonstrated by classical Y2H. xref: IntAct:EBI-491359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005804 ! DHX9_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN [Term] id: CCO:I0019243 name: trib1-map2k4-1 physical interaction comment: Interaction detected by co-immunoprecipitation xref: IntAct:EBI-492587 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006002 ! TRIB1_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN [Term] id: CCO:I0019244 name: trib3-map2k7-1 physical interaction comment: Interaction detected by co-immunoprecipitation xref: IntAct:EBI-492631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0020951 ! MP2K7_HUMAN [Term] id: CCO:I0019245 name: tnfrsf1a-tradd-7 physical interaction comment: co-IP: bait = human TNFR1, prey = human TRADD xref: IntAct:EBI-518096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN [Term] id: CCO:I0019246 name: birc7-diablo-7 physical interaction comment: Co-IP: bait = biotinylated SMAC peptide, prey = ML-IAP xref: IntAct:EBI-523823 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0019247 name: birc4-diablo-2 physical interaction comment: Co-IP: bait = biotinylated SMAC peptide, prey = X-IAP xref: IntAct:EBI-523839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0019248 name: birc2-casp9-1 physical interaction comment: Co-IP: bait = C-IAP1, prey = caspase 9 xref: IntAct:EBI-524015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005903 ! CASP9_HUMAN [Term] id: CCO:I0019249 name: birc7-casp9-4 physical interaction comment: Co-IP: bait = ML-IAP1, prey = caspase 9 xref: IntAct:EBI-524040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN [Term] id: CCO:I0019250 name: erbb4-dlg4-4 physical interaction comment: Interaction detected by coimmunoprecipitation. xref: IntAct:EBI-525167 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:I0019251 name: raf1-ywhab physical interaction comment: Y2H: bait = C-Raf ,prey = 14-3-3beta xref: IntAct:EBI-537195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0019252 name: sin3a-sfpq-2 physical interaction xref: IntAct:EBI-591436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0019253 name: cdc42-itsn1-1 direct interaction comment: X-Ray : crystal of the complex Cdc42 and the GEF Intersectin 1 (itsn1) xref: IntAct:EBI-602095 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0019254 name: epor-plcg21-2 physical interaction comment: Interaction between human EpoR and PLCgamma2 demonstrated by MAPPIT xref: IntAct:EBI-617590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055061 ! PLCG2_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN [Term] id: CCO:I0019255 name: insr-sorbs-1 physical interaction comment: Interaction between SORB1 and the insulin receptor demonstrated by coimmunoprecipitation xref: IntAct:EBI-624105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005641 ! SRBS1_HUMAN [Term] id: CCO:I0019256 name: btk-sh3bp5-1 physical interaction comment: Interaction between BTK and SH3BP5 (SAB) identified by coimmunoprcipitation xref: IntAct:EBI-624868 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0019257 name: btk-gtf21-4 physical interaction comment: Interaction between BTK and GTF21 (BAP135) identified by coimmunoprecipitation xref: IntAct:EBI-625164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN [Term] id: CCO:I0019258 name: notch1-skiip-1 physical interaction comment: NotchIC interacts with SKIP, as detected by coimmunoprecipitation. xref: IntAct:EBI-636394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0048571 ! SNW1_HUMAN [Term] id: CCO:I0019259 name: smarca4-arid2-1 physical interaction comment: coIP: bait = brg1, prey = baf200 xref: IntAct:EBI-637959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0019260 name: smarce1-arid2-1 physical interaction comment: coIP: bait = baf57, prey = baf200 xref: IntAct:EBI-637963 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN [Term] id: CCO:I0019261 name: dmpk-pln-1 phosphorylation comment: Phosphorylation of phospholamban by DMPK xref: IntAct:EBI-692834 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0055804 ! DMPK_HUMAN relationship: has_participant CCO:B0063298 ! PPLA_HUMAN [Term] id: CCO:I0019262 name: dmpk-pln-2 phosphorylation comment: Phosphorylation of phospholamban by DMPK xref: IntAct:EBI-692852 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0055804 ! DMPK_HUMAN relationship: has_participant CCO:B0063298 ! PPLA_HUMAN [Term] id: CCO:I0019263 name: ikka-src-3 physical interaction comment: cSRC is a component of the IKK complex xref: IntAct:EBI-697983 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0019264 name: atx2-pabp-2 physical interaction comment: Co-localisation analysis reveals interaction between the ataxin-2 protein and PABP protein xref: IntAct:EBI-698747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN [Term] id: CCO:I0019265 name: itga2b-itga2b-4 direct interaction comment: SDS-PAGE: Oligomerization of alpha II b integrin xref: IntAct:EBI-702835 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN [Term] id: CCO:I0019266 name: itgb3-itgb3-1 direct interaction comment: SDS-PAGE: Oligomerization of integrin beta3 xref: IntAct:EBI-702877 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0033141 ! ITB3_HUMAN [Term] id: CCO:I0019267 name: app-apoa-6 physical interaction comment: Interaction of apoA-1 and amyloid beta detected by solid-phase ELISA assays. xref: IntAct:EBI-703781 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN [Term] id: CCO:I0019268 name: prkd-fyn-1 physical interaction comment: Interaction between PKC delta and FYN demonstrated by coimmunoprecipitation xref: IntAct:EBI-706296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:I0019269 name: prkd-fyn-2 physical interaction comment: Interaction between PKC delta and FYN demonstrated by coimmunoprecipitation xref: IntAct:EBI-706300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0055745 ! KPCD_HUMAN [Term] id: CCO:I0019270 name: bim-bclw-2 direct interaction comment: Interaction of BIM with BCL-w by biacore xref: IntAct:EBI-707852 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006003 ! BIM_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019271 name: bbc3-bclw-1 direct interaction comment: Interaction of BBC3 with BCL-w by biacore xref: IntAct:EBI-707968 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019272 name: bad-bclw-1 direct interaction comment: Interaction of BAD with BCL-w by biacore xref: IntAct:EBI-708100 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005175 ! BAD_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019273 name: bik-bclw-2 direct interaction comment: Interaction of BIK with BCL-w by biacore xref: IntAct:EBI-708122 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019274 name: hrk-bclw-1 direct interaction comment: Interaction of HRK with BCL-w by biacore xref: IntAct:EBI-708154 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0028585 ! BCLW_HUMAN relationship: has_participant CCO:B0054298 ! HRK_HUMAN [Term] id: CCO:I0019275 name: bid-bclw-2 direct interaction comment: Interaction of BID with BCL-w by biacore xref: IntAct:EBI-708186 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019276 name: atxn7-trrap-2 acetylation comment: HAT assay reveals Ataxin 7 can acetylate free histones. xref: IntAct:EBI-708479 is_a: CCO:Y0000002 ! acetylation reaction relationship: has_participant CCO:B0005221 ! H31_HUMAN relationship: has_participant CCO:B0005771 ! H2B1C_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0019277 name: muc7-lama5 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the Mucin 7 protein and LAMA5 protein xref: IntAct:EBI-738663 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054418 ! LAMA5_HUMAN relationship: has_participant CCO:B0063343 ! MUC7_HUMAN [Term] id: CCO:I0019278 name: muc7-pfn2 physical interaction comment: Yeast 2 hybrid analysis reveals interaction between the Mucin 7 protein and PFN2 protein xref: IntAct:EBI-738669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0063343 ! MUC7_HUMAN [Term] id: CCO:I0019279 name: phlda1-eif3s7-1 physical interaction xref: IntAct:EBI-738754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026270 ! EIF3D_HUMAN relationship: has_participant CCO:B0062957 ! PHLA1_HUMAN [Term] id: CCO:I0019280 name: fyn-fyn-10 phosphorylation comment: Autophosphorylation of fyn is activated by NS5A protein hepatitis C Virus (similar to isolate Con1) xref: IntAct:EBI-762543 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005609 ! FYN_HUMAN [Term] id: CCO:I0019281 name: lyn-lyn-2 phosphorylation comment: Autophosphorylation of lyn is inhibited by NS5A protein hepatitis C Virus (similar to isolate Con1) xref: IntAct:EBI-762547 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005457 ! LYN_HUMAN [Term] id: CCO:I0019282 name: gan-map1b-2 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the Gigaxonin protein and MAP1B protein xref: IntAct:EBI-764641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055380 ! MAP1B_HUMAN relationship: has_participant CCO:B0063005 ! GAN_HUMAN [Term] id: CCO:I0019283 name: nrbp-rac3-3 physical interaction comment: Interaction of NRBP with Rac3 identifed by colocalisation xref: IntAct:EBI-767115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025814 ! RAC3_HUMAN relationship: has_participant CCO:B0062919 ! NRBP_HUMAN [Term] id: CCO:I0019284 name: edf1-nr1h3-1 physical interaction comment: MBF-1 interacts in vitro with LXR-alpha, as detected by pull-down experiments. xref: IntAct:EBI-781379 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054582 ! EDF1_HUMAN relationship: has_participant CCO:B0055878 ! NR1H3_HUMAN [Term] id: CCO:I0019285 name: erbb4-dlg4-2 physical interaction comment: Interaction detected by coimmunoprecipitation. xref: IntAct:EBI-80768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0023311 ! DLG4_HUMAN [Term] id: CCO:I0019286 name: pabp-paip1 physical interaction comment: Paip1 interacts with poly(A) binding protein through two independent binding motifs xref: IntAct:EBI-81544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN [Term] id: CCO:I0019287 name: paip1-pabp physical interaction comment: Paip1 interacts with poly(A) binding protein through two independent binding motifs xref: IntAct:EBI-81548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN [Term] id: CCO:I0019288 name: flna-flnb-5 physical interaction comment: CoIP: bait = Filamin A, prey = Filamin B xref: IntAct:EBI-852083 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN [Term] id: CCO:I0019289 name: polg-polg2-2 physical interaction comment: Stoichiometry of POLG and POLG2 identified by gel filtration xref: IntAct:EBI-852726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:I0019290 name: crebbp-nap1l1-1 physical interaction xref: IntAct:EBI-914392 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0019291 name: dnmt1-ezh2 physical interaction xref: IntAct:EBI-923761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0019292 name: dnmt3a-ezh2 physical interaction xref: IntAct:EBI-923769 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0019293 name: dnmt3b-ezh2 physical interaction xref: IntAct:EBI-923772 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0019294 name: dnmt1-ezh2-1 physical interaction xref: IntAct:EBI-923787 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0019295 name: disc1-atf4-2 physical interaction comment: Mammalian 2 hybrid analysis reveals interaction between the DISC1 protein and ATF4 protein xref: IntAct:EBI-930699 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005591 ! DISC1_HUMAN relationship: has_participant CCO:B0021435 ! ATF4_HUMAN [Term] id: CCO:I0019296 name: leo1-ctnnb1-4 physical interaction xref: IntAct:EBI-932438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0057990 ! LEO1_HUMAN [Term] id: CCO:I0019297 name: ebox-hash1-e2_2-1 direct interaction comment: Interaction between human HASH-1, E2-2 and E-box DNA detected by EMSA xref: IntAct:EBI-957214 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:I0019298 name: st5-grb2-1 physical interaction xref: IntAct:EBI-962667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0006063 ! ST5_HUMAN [Term] id: CCO:I0019299 name: fam48a-mapk14-1 physical interaction xref: IntAct:EBI-970448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0063193 ! FA48A_HUMAN [Term] id: CCO:I0019300 name: fam48a-mapk14-2 physical interaction xref: IntAct:EBI-970475 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0063193 ! FA48A_HUMAN [Term] id: CCO:I0019301 name: birc2-traf2-3 physical interaction comment: Interaction between BIRC2 (cIAP1) and TRAF2 identified by coimmunoprecipitation xref: IntAct:EBI-977074 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0019302 name: birc3-traf2-2 physical interaction comment: Interaction between BIRC3 (cIAP2) and TRAF2 identified by pulldown xref: IntAct:EBI-977095 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0055917 ! BIRC3_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0019303 name: app-app colocalization xref: IntAct:EBI-977478 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005474 ! A4_HUMAN [Term] id: CCO:I0019304 name: pex26-pex6 physical interaction comment: Coimmunoprecipitation reveals Pex26 interacts with Pex6 xref: IntAct:EBI-980993 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005312 ! PEX26_HUMAN relationship: has_participant CCO:B0026912 ! PEX6_HUMAN [Term] id: CCO:I0019305 name: adamts13-vwf protein cleavage xref: IntAct:EBI-981807 is_a: CCO:Y0000039 ! protein cleavage relationship: has_participant CCO:B0031878 ! VWF_HUMAN relationship: has_participant CCO:B0057108 ! ATS13_HUMAN [Term] id: CCO:I0019306 name: dicer1-tarbp2-8 physical interaction xref: IntAct:EBI-981811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0019307 name: adamts13-vwf-8 protein cleavage xref: IntAct:EBI-982071 is_a: CCO:Y0000039 ! protein cleavage relationship: has_participant CCO:B0031878 ! VWF_HUMAN relationship: has_participant CCO:B0057108 ! ATS13_HUMAN [Term] id: CCO:I0019308 name: adamts13-vwf-9 protein cleavage xref: IntAct:EBI-982419 is_a: CCO:Y0000039 ! protein cleavage relationship: has_participant CCO:B0031878 ! VWF_HUMAN relationship: has_participant CCO:B0057108 ! ATS13_HUMAN [Term] id: CCO:I0019309 name: ctnnb1-psen1-1 physical interaction xref: IntAct:EBI-988996 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0019310 name: jup-psen1 physical interaction xref: IntAct:EBI-989017 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0019311 name: jup-psen1-2 physical interaction xref: IntAct:EBI-989446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN [Term] id: CCO:I0019312 name: hsf1-mk2-3 physical interaction xref: IntAct:EBI-993595 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026467 ! HSF1_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN [Term] id: CCO:I0019313 name: il1rl1-c9orf26-1 direct interaction xref: IntAct:EBI-994012 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055691 ! ILRL1_HUMAN relationship: has_participant CCO:B0063254 ! IL33_HUMAN [Term] id: CCO:I0019314 name: sub1-cstf2-1 physical interaction xref: IntAct:EBI-998274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0048676 ! TCP4_HUMAN relationship: has_participant CCO:B0063344 ! CSTF2_HUMAN [Term] id: CCO:I0019315 name: nmdar1-plcb4 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between NMDAR1 protein and PLCB4 protein xref: IntAct:EBI-998685 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055744 ! NMDZ1_HUMAN relationship: has_participant CCO:B0056047 ! PLCB4_HUMAN [Term] id: CCO:I0019316 name: erbb2-erbb2 physical interaction xref: IntAct:EBI-1000502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN [Term] id: CCO:I0019317 name: flt4-kdr physical interaction xref: IntAct:EBI-1005528 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055304 ! VGFR3_HUMAN relationship: has_participant CCO:B0055305 ! VGFR2_HUMAN [Term] id: CCO:I0019318 name: flt4-kdr-1 physical interaction xref: IntAct:EBI-1005535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055304 ! VGFR3_HUMAN relationship: has_participant CCO:B0055305 ! VGFR2_HUMAN [Term] id: CCO:I0019319 name: cbfb-runx1-1 direct interaction comment: Aml1-cbf complex xref: IntAct:EBI-1025903 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0033619 ! RUNX1_HUMAN relationship: has_participant CCO:B0063345 ! PEBB_HUMAN [Term] id: CCO:I0019320 name: gh1-ghr-1 direct interaction comment: 1:2 complex of human growth hormone with its soluble binding protein xref: IntAct:EBI-1026225 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054843 ! SOMA_HUMAN relationship: has_participant CCO:B0063273 ! GHR_HUMAN [Term] id: CCO:I0019321 name: gh1-ghr-2 direct interaction comment: 1:1 complex of human growth hormone mutant g120r with its soluble binding protein xref: IntAct:EBI-1026236 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0054843 ! SOMA_HUMAN relationship: has_participant CCO:B0063273 ! GHR_HUMAN [Term] id: CCO:I0019322 name: rpa2-rpa3-2 direct interaction comment: Complex of replication protein a subunits rpa14 and rpa32 xref: IntAct:EBI-1028047 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005501 ! RFA3_HUMAN [Term] id: CCO:I0019323 name: birc4-casp7-2 direct interaction comment: Crystal structure of the xiap/caspase-7 complex xref: IntAct:EBI-1030903 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055530 ! CASP7_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:I0019324 name: rhoa-rock1-1 direct interaction comment: Crystal structure of the complex between the human rhoa and rho-binding domain of human rocki xref: IntAct:EBI-1037622 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0055910 ! ROCK1_HUMAN [Term] id: CCO:I0019325 name: smad2-smad4-2 direct interaction comment: Crystal structure of the phosphorylated smad2-smad4 heterotrimeric complex xref: IntAct:EBI-1040189 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN [Term] id: CCO:I0019326 name: fnbp1-tnks-2 physical interaction xref: IntAct:EBI-1111296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005386 ! FNBP1_HUMAN relationship: has_participant CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:I0019327 name: s100a1-s100p-4 colocalization xref: IntAct:EBI-1148974 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0055155 ! S10A1_HUMAN relationship: has_participant CCO:B0062804 ! S100P_HUMAN [Term] id: CCO:I0019328 name: cftr-slc9a3r2 physical interaction xref: IntAct:EBI-1149754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0025069 ! NHRF2_HUMAN [Term] id: CCO:I0019329 name: cftr-slc9a3r2-1 physical interaction xref: IntAct:EBI-1149800 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0025069 ! NHRF2_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN [Term] id: CCO:I0019330 name: rfc_human physical interaction comment: DNA replication factor C complex xref: IntAct:EBI-1170110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN [Term] id: CCO:I0019331 name: map2k4-mapk8-1 direct interaction comment: Interaction between MAP2K4 and MAPK8 identified by pulldown xref: IntAct:EBI-1170802 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005638 ! MK08_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN [Term] id: CCO:I0019332 name: asgr1-lass2 direct interaction comment: GST-AGPRH1 pulls down LASS2 xref: IntAct:EBI-1172776 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0019141 ! ASGR1_HUMAN relationship: has_participant CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:I0019333 name: asgr2-lass2 direct interaction comment: GST-AGPRH2 pulls down LASS2 xref: IntAct:EBI-1172835 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0019143 ! ASGR2_HUMAN relationship: has_participant CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:I0019334 name: hoct1-lass2-1 direct interaction comment: GST-VPL pulls down LASS2 xref: IntAct:EBI-1172876 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0028140 ! VATL_HUMAN relationship: has_participant CCO:B0033375 ! LASS2_HUMAN [Term] id: CCO:I0019335 name: wnk3-casp3-2 physical interaction comment: Interaction between WNK3 and Caspase-3 identified by coimmunoprecipitation xref: IntAct:EBI-1182655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055351 ! CASP3_HUMAN relationship: has_participant CCO:B0058581 ! WNK3_HUMAN [Term] id: CCO:I0019336 name: all1-all1-2 direct interaction xref: IntAct:EBI-1203386 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005486 ! HRX_HUMAN [Term] id: CCO:I0019337 name: st7-gnb2l1-1 physical interaction comment: Interaction between ST7 and GNB2L1 detected by Y2H xref: IntAct:EBI-296801 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005739 ! GBLP_HUMAN relationship: has_participant CCO:B0059369 ! LRP12_HUMAN [Term] id: CCO:I0019338 name: st7-madhip-1 physical interaction comment: Interaction between ST7 and MADHIP detected by Y2H xref: IntAct:EBI-296833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054758 ! ZFYV9_HUMAN relationship: has_participant CCO:B0059369 ! LRP12_HUMAN [Term] id: CCO:I0019339 name: eif4e-4et physical interaction comment: A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E xref: IntAct:EBI-301015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006012 ! 4ET_HUMAN relationship: has_participant CCO:B0016186 ! IF4E_HUMAN [Term] id: CCO:I0019340 name: q9umf9-eif3s4-1 physical interaction comment: The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro xref: IntAct:EBI-366663 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026269 ! EIF3G_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0019341 name: q9umf9-eif3s2-1 physical interaction comment: The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro xref: IntAct:EBI-366669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026269 ! EIF3G_HUMAN relationship: has_participant CCO:B0026273 ! EIF3I_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0019342 name: eif3s2-eif3s1-1 physical interaction comment: The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro xref: IntAct:EBI-366676 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026273 ! EIF3I_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0019343 name: abi1-nckap1-2 physical interaction xref: IntAct:EBI-389854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0050612 ! NCKP1_HUMAN [Term] id: CCO:I0019344 name: emx2-eif4e-2 physical interaction comment: Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons xref: IntAct:EBI-399863 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055734 ! EMX2_HUMAN [Term] id: CCO:I0019345 name: raf1-ywhaz-1 physical interaction comment: GST pull-down : bailt = human 14-3-3-GST , prey= raf1 xref: IntAct:EBI-445314 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0019346 name: cdc42-was-4 direct interaction comment: RMN : human cdc42 and human WASP xref: IntAct:EBI-457550 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0019347 name: cdc42-iqgap1-1 physical interaction comment: MBP pull down, Bait = human Cdc42, Prey = in vitro translated human IQGAP1 xref: IntAct:EBI-457807 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN [Term] id: CCO:I0019348 name: smndc1-kpnb1 physical interaction comment: Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein xref: IntAct:EBI-464916 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0054679 ! SPF30_HUMAN [Term] id: CCO:I0019349 name: smndc1-kpnb1-2 physical interaction comment: Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein xref: IntAct:EBI-464937 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005409 ! IMB1_HUMAN relationship: has_participant CCO:B0054679 ! SPF30_HUMAN [Term] id: CCO:I0019350 name: cdc42-was-6 physical interaction comment: fluorescence changes: WASP CRIB labelled with an iodoacetamide dye and cdc42 xref: IntAct:EBI-476854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0062975 ! WASP_HUMAN [Term] id: CCO:I0019351 name: rac1-pak1-3 direct interaction comment: FRET: GFP-Rac1 and PAK1 PDB domain labelled with Alexa-546 dye xref: IntAct:EBI-476880 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:I0019352 name: srf-myocd-1 physical interaction comment: Interaction detected by gel mobility shift assay xref: IntAct:EBI-493265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0057412 ! MYCD_HUMAN [Term] id: CCO:I0019353 name: srf-myocd-2 physical interaction comment: Interaction detected by GST pulldown xref: IntAct:EBI-493415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0057412 ! MYCD_HUMAN [Term] id: CCO:I0019354 name: srf-mlk1-1 physical interaction comment: Interaction detected by GST pulldown xref: IntAct:EBI-493430 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0058143 ! MKL1_HUMAN [Term] id: CCO:I0019355 name: srf-mlk2-1 physical interaction comment: Interaction detected by GST pulldown xref: IntAct:EBI-493438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0059226 ! MKL2_HUMAN [Term] id: CCO:I0019356 name: mark2-ywhaz-1 physical interaction comment: Interaction between MARK2 and YWHAZ demonstated by coimmunopreciptiation xref: IntAct:EBI-516573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0037391 ! MARK2_HUMAN [Term] id: CCO:I0019357 name: omi-xiap physical interaction comment: The XIAP protein interacts with the Omi/HtrA2 protein xref: IntAct:EBI-517125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0063244 ! HTRA2_HUMAN [Term] id: CCO:I0019358 name: omi-xiap-1 physical interaction comment: The XIAP protein interacts with a peptide which mimics the Omi/HtrA2 amino terminal region xref: IntAct:EBI-517144 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0063244 ! HTRA2_HUMAN [Term] id: CCO:I0019359 name: tac1-blys-1 physical interaction comment: The B-lymphocyte stimulator (BlyS) protein interacts with the tumor necrosis factor receptor superfamily member TAC1 xref: IntAct:EBI-519339 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:I0019360 name: cdh_3-cgi physical interaction comment: GST pulldown reveals in vitro interaction between the C terminal region of the chromodomain helicase-DNA-binding protein 3 and the plasminogen activator inhibitor 1 RNA-binding protein (CGI-55) xref: IntAct:EBI-523681 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:I0019361 name: birc7-diablo-8 physical interaction comment: Co-IP: bait = ML-IAP, prey = SMAC xref: IntAct:EBI-523869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:I0019362 name: dicer1-eif2c2-4 physical interaction xref: IntAct:EBI-528608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0016049 ! I2C2_HUMAN relationship: has_participant CCO:B0019368 ! PIWL4_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0019363 name: tirap-myd88 physical interaction comment: Directed yeast-2-hybrid reveals interaction between the toll-interleukin 1 receptor domain-containing adapter protein and the Myeloid differentiation primary response protein (MyD88) xref: IntAct:EBI-528658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055572 ! TIRAP_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0019364 name: myd88-tirap physical interaction comment: Directed yeast-2-hybrid reveals interaction between the myeloid differentiation primary response protein (MyD88) and the toll-interleukin 1 receptor domain-containing adapter protein xref: IntAct:EBI-528661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055572 ! TIRAP_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0019365 name: myd88 physical interaction comment: Directed yeast-2-hybrid reveals that the myeloid differentiation primary response protein (MyD88) forms homotypic associations xref: IntAct:EBI-528671 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:I0019366 name: msn-nherf-1 direct interaction comment: Crystal of the FERM domain of Moesin and the C-terminus of EBP50 xref: IntAct:EBI-528781 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0018220 ! MOES_HUMAN relationship: has_participant CCO:B0025071 ! NHERF_HUMAN [Term] id: CCO:I0019367 name: taj-traf1 physical interaction comment: Coimmunoprecipitaion reveals interaction between Tumor necrosis factor receptor superfamily member 19 precursor (TAJ) and the TNF receptor associated factor 1 (TRAF1) xref: IntAct:EBI-530343 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0058911 ! TNR19_HUMAN [Term] id: CCO:I0019368 name: taj-traf2 physical interaction comment: Coimmunoprecipitaion reveals interaction between Tumor necrosis factor receptor superfamily member 19 precursor (TAJ) and the TNF receptor associated factor 2 (TRAF2) xref: IntAct:EBI-530352 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0058911 ! TNR19_HUMAN [Term] id: CCO:I0019369 name: traf5-taj physical interaction comment: Coimmunoprecipitaion reveals interaction between the TNF receptor associated factor 5 (TRAF5) and the Tumor necrosis factor receptor superfamily member 19 precursor (TAJ) protein xref: IntAct:EBI-530364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN relationship: has_participant CCO:B0058911 ! TNR19_HUMAN [Term] id: CCO:I0019370 name: raf1-efemp1 physical interaction comment: Y2H: bait = C-Raf ,prey = FBNL-FBL3_HUMAN xref: IntAct:EBI-537251 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005955 ! FBLN3_HUMAN [Term] id: CCO:I0019371 name: raf1-pkm2-1 physical interaction comment: Y2H: bait = C-Raf ,prey = PyK-KPYM_HUMAN xref: IntAct:EBI-537258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063029 ! KPYM_HUMAN [Term] id: CCO:I0019372 name: raf1-nudt14 physical interaction comment: Y2H: bait = C-Raf ,prey = hA21-NU14_HUMAN-UGPPase xref: IntAct:EBI-537279 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063253 ! NUD14_HUMAN [Term] id: CCO:I0019373 name: raf1-cops3 physical interaction comment: Y2H: bait = C-Raf ,prey = SGN3-COP9 complex subunit 3 xref: IntAct:EBI-537286 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN [Term] id: CCO:I0019374 name: raf1-rras2 physical interaction comment: Y2H: bait = C-Raf ,prey = R-RAS xref: IntAct:EBI-537300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN [Term] id: CCO:I0019375 name: raf1-cps1 physical interaction comment: Y2H: bait = C-Raf ,prey = CPS1-CPSM_HUMAN xref: IntAct:EBI-537307 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063232 ! CPSM_HUMAN [Term] id: CCO:I0019376 name: raf1-ywhab-2 physical interaction comment: Y2H: bait = C-Raf ,prey = 14-3-3 beta xref: IntAct:EBI-537314 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0019377 name: raf1-cct3-1 physical interaction comment: Y2H: bait = C-Raf ,prey = CCT3-TCPG_HUMAN xref: IntAct:EBI-537328 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN [Term] id: CCO:I0019378 name: raf1-oip5-1 physical interaction comment: Y2H: bait = C-Raf ,prey = OIP5-OIP5_HUMAN xref: IntAct:EBI-537335 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0063028 ! OIP5_HUMAN [Term] id: CCO:I0019379 name: pex19-pex11b-1 physical interaction comment: PEX19 binds multiple integral PMPs, as detected by Y2H. xref: IntAct:EBI-594832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005820 ! PEX19_HUMAN relationship: has_participant CCO:B0054820 ! PX11B_HUMAN [Term] id: CCO:I0019380 name: pfta-rap2-1 physical interaction comment: X-Ray: Human Farnesyl transferase complexed with Rap2A c-terminus peptide (containing CAAX motif) xref: IntAct:EBI-602363 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024404 ! RAP2A_HUMAN relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:I0019381 name: pkn1-mapk14-1 physical interaction comment: Weak interaction between PKN1 and p38alpha detected by coimmunoprecipitation xref: IntAct:EBI-602400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006068 ! PKN1_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN [Term] id: CCO:I0019382 name: pkn1-map2k3-1 physical interaction comment: Interaction between PKN1 and MKK3 detected by coimmunoprecipitation xref: IntAct:EBI-602493 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006068 ! PKN1_HUMAN relationship: has_participant CCO:B0020948 ! MP2K3_HUMAN [Term] id: CCO:I0019383 name: cdc42-pak1-6 physical interaction comment: CoIP : bait=pak1 , prey = cdc42 xref: IntAct:EBI-602824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0005469 ! PAK1_HUMAN [Term] id: CCO:I0019384 name: stk25-ywhaz -1 phosphorylation comment: Phosphorylation of YWHAZ by Ysk1 xref: IntAct:EBI-618399 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0022748 ! STK25_HUMAN [Term] id: CCO:I0019385 name: hdac1-rbbp7-1 physical interaction comment: Co-ip of interaction between hdac1 and rbbp7 (RbAp46). xref: IntAct:EBI-620844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005809 ! RBBP7_HUMAN [Term] id: CCO:I0019386 name: hdac1-hdac1-1 physical interaction comment: Co-ip of interaction between hdac1 and hdac1. xref: IntAct:EBI-630259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0019387 name: hdac1-hdac2-2 physical interaction comment: Co-ip of interaction between hdac1 and hdac2. xref: IntAct:EBI-630267 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN [Term] id: CCO:I0019388 name: rbpsuh-notch1-1 physical interaction comment: SMRT displaces NotchIC from both CBF1 and SKIP, as determined by mammalian two hybrid. xref: IntAct:EBI-636557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN [Term] id: CCO:I0019389 name: erbb2-pik3c2a-1 physical interaction comment: Interaction of PIK3C2A , PIK3C2B and ERBB2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-641125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN relationship: has_participant CCO:B0006071 ! P3C2A_HUMAN [Term] id: CCO:I0019390 name: pdgfr-pik3c2b-1 physical interaction comment: Interaction of PIK3C2B and PDGFR demonstrated by coimmunoprecipitation xref: IntAct:EBI-641254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN [Term] id: CCO:I0019391 name: cdc42bpa-cd42bpa-3 direct interaction comment: Dimer formation by CDC42BPA demonstrated by coimmunoprecipitation xref: IntAct:EBI-689355 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0019392 name: cdc42bpa-cd42bpa-4 direct interaction comment: Dimer formation by CDC42BPA demonstrated by coimmunoprecipitation xref: IntAct:EBI-689394 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0019393 name: cdc42bpa-cd42bpa-6 direct interaction comment: Dimer formation by CDC42BPA demonstrated by coimmunoprecipitation xref: IntAct:EBI-692004 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0019394 name: cdc42bpa-cd42bpa-9 direct interaction comment: Dimer formation by CDC42BPA demonstrated by coimmunoprecipitation xref: IntAct:EBI-692053 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN [Term] id: CCO:I0019395 name: tcp1-atx2-3 physical interaction comment: Colocalisation reveals interaction between T-Plastin and ataxin-2 xref: IntAct:EBI-698636 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0019585 ! PLST_HUMAN [Term] id: CCO:I0019396 name: lcp1-atx2-2 physical interaction comment: Colocalisation reveals interaction between L-Plastin and ataxin-2 xref: IntAct:EBI-698640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0019594 ! PLSL_HUMAN [Term] id: CCO:I0019397 name: wrn-g22p1-4 physical interaction comment: In vitro co-IP: bait= WRN c-terminus , prey = Ku86, ku70 xref: IntAct:EBI-707517 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0019398 name: wrn-fen1-5 direct interaction comment: ELISA: bait = WRN, probe = FEN-1 xref: IntAct:EBI-708264 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0019399 name: wrn-fen1-7 colocalization comment: Colocalization between WRN and FEN-1 in HeLa cells xref: IntAct:EBI-708308 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0019400 name: atxn7-trrap-1 physical interaction comment: Ataxin 7 protein and TRRAP, TAF10 the GCN5 proteins are present in the TCTF complex xref: IntAct:EBI-708454 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN [Term] id: CCO:I0019401 name: pfkfb1-pfkb1_human direct interaction comment: 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase 1 homodimer xref: IntAct:EBI-709843 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0033471 ! F261_HUMAN [Term] id: CCO:I0019402 name: aof2-immt-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005589 ! LSD1_HUMAN relationship: has_participant CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:I0019403 name: c10orf4-map3k12-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018778 ! M3K12_HUMAN relationship: has_participant CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:I0019404 name: emd-sh3gl2-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710249 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:I0019405 name: mark3-tcea2-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710306 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005229 ! MARK3_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0019406 name: ptpn4-htatip-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063349 ! PTN4_HUMAN [Term] id: CCO:I0019407 name: sh3gl1-dppa4-1 physical interaction comment: Interaction detected by His pull down. xref: IntAct:EBI-710453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN relationship: has_participant CCO:B0062834 ! DPPA4_HUMAN [Term] id: CCO:I0019408 name: hoxa9-trip6-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760490 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0055236 ! HXA9_HUMAN [Term] id: CCO:I0019409 name: cart1-cart1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760595 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056097 ! ALX1_HUMAN relationship: has_participant CCO:B0062870 ! IPO13_HUMAN [Term] id: CCO:I0019410 name: rgr-kiaa1279 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043863 ! KBP_HUMAN relationship: has_participant CCO:B0055386 ! RGR_HUMAN [Term] id: CCO:I0019411 name: gage8-gmcl1l-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760644 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033871 ! GAGE8_HUMAN relationship: has_participant CCO:B0057588 ! GMCLL_HUMAN [Term] id: CCO:I0019412 name: plod3-pepp2 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0062790 ! PLOD3_HUMAN [Term] id: CCO:I0019413 name: tcea2-magea11 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760665 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005212 ! MAGAB_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0019414 name: zmynd10-tsc22d4 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760714 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0062863 ! ZMY10_HUMAN [Term] id: CCO:I0019415 name: ushbp1-sertad3 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005210 ! USBP1_HUMAN relationship: has_participant CCO:B0059180 ! SRTD3_HUMAN [Term] id: CCO:I0019416 name: tuba2-nmi physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760749 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0024576 ! TBA3C_HUMAN [Term] id: CCO:I0019417 name: pcbd1-pcbd1-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055611 ! PHS_HUMAN [Term] id: CCO:I0019418 name: dvl2-dvl2-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN [Term] id: CCO:I0019419 name: efemp2-pepp2-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760805 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005215 ! FBLN4_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN [Term] id: CCO:I0019420 name: ube2d4-dtx2 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019459 ! UB2D4_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN [Term] id: CCO:I0019421 name: ablim1-ldoc1-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760840 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0027190 ! ABLM1_HUMAN [Term] id: CCO:I0019422 name: stmn2-tex11-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005187 ! TEX11_HUMAN relationship: has_participant CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:I0019423 name: zbtb25-mdf1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760903 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0055169 ! ZBT25_HUMAN [Term] id: CCO:I0019424 name: tmem11-bnip3 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760959 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0055084 ! TMM11_HUMAN [Term] id: CCO:I0019425 name: mgc4504-pepp2-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760973 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0062948 ! CHAC1_HUMAN [Term] id: CCO:I0019426 name: dvl2-znf165-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760987 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0019427 name: mapk14-zfp36l1-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-760994 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0026498 ! TISB_HUMAN [Term] id: CCO:I0019428 name: rad23a-sqstm1-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-761029 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN relationship: has_participant CCO:B0062849 ! RD23A_HUMAN [Term] id: CCO:I0019429 name: ppfia1-ppp2r5d-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-761043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN relationship: has_participant CCO:B0031630 ! LIPA1_HUMAN [Term] id: CCO:I0019430 name: six1-mdf1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-761057 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0056069 ! SIX1_HUMAN [Term] id: CCO:I0019431 name: ewsr1-znf165-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-761064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN [Term] id: CCO:I0019432 name: nol3-nol3-1 physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-761085 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054591 ! NOL3_HUMAN [Term] id: CCO:I0019433 name: tesc-hmg20a physical interaction comment: Part of the co-AP dataset. xref: IntAct:EBI-761120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005296 ! HM20A_HUMAN relationship: has_participant CCO:B0062775 ! TESC_HUMAN [Term] id: CCO:I0019434 name: ku70_80_human direct interaction comment: Ku70:Ku80 heterodimer xref: IntAct:EBI-761759 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN [Term] id: CCO:I0019435 name: pfkm-pfkl3_human physical interaction comment: 6-phosphofructokinase, ML3 heterotetramer xref: IntAct:EBI-764890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0019436 name: pfkm2-pfkl2_human physical interaction comment: 6-phosphofructokinase, M2L2 heterotetramer xref: IntAct:EBI-764901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0019437 name: pfkm3-pfkl1_human physical interaction comment: 6-phosphofructokinase, M3L heterotetramer xref: IntAct:EBI-764934 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN [Term] id: CCO:I0019438 name: adam15-sh3gl2-3 physical interaction xref: IntAct:EBI-78016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005909 ! ADA15_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0019439 name: pax6-homer3-1 physical interaction comment: Y2H: bait = PAX6 c-terminus peptide, prey =HOMER3 xref: IntAct:EBI-851752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0058915 ! HOME3_HUMAN [Term] id: CCO:I0019440 name: pax6-homer3-2 physical interaction comment: Y2H: bait = PAX6 PST domain, prey = HOMER3 xref: IntAct:EBI-851803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0058915 ! HOME3_HUMAN [Term] id: CCO:I0019441 name: pax6-trim11-1 physical interaction comment: Y2H: bait = PAX6 PST domain, prey = Trim11 xref: IntAct:EBI-851832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0063350 ! TRI11_HUMAN [Term] id: CCO:I0019442 name: polg-polg2-5 physical interaction comment: Kinetics of POLG binding to POLG2 measured by surface plasmon resonance xref: IntAct:EBI-852789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:I0019443 name: polg-polg2-6 physical interaction comment: Kinetics of POLG binding to POLG2 measured by surface plasmon resonance xref: IntAct:EBI-852806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:I0019444 name: dpol-gamma_human physical interaction comment: DNA polymerase gamma heterotrimer xref: IntAct:EBI-863465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:I0019445 name: eif4e-gemin5 direct interaction xref: IntAct:EBI-876635 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0062979 ! GEMI5_HUMAN [Term] id: CCO:I0019446 name: hdac1-rfx1 physical interaction xref: IntAct:EBI-923319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0006243 ! RFX1_HUMAN [Term] id: CCO:I0019447 name: baz1b-smarca5 physical interaction xref: IntAct:EBI-927537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0058901 ! BAZ1A_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN [Term] id: CCO:I0019448 name: eif4e-eif4g1-1 direct interaction comment: Interaction between eIF4E and eIF4G1 demonstrated by S-protein pulldown xref: IntAct:EBI-928154 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0019449 name: mx1-trpc6-3 physical interaction comment: GST pull-down: bait = MxA, prey = TRPC6 ARD domain xref: IntAct:EBI-929448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0062980 ! TRPC6_HUMAN [Term] id: CCO:I0019450 name: mx1-trpc3-1 physical interaction comment: GST pull-down: bait =MxA, prey = TRPC3 ARD domain xref: IntAct:EBI-929460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0063192 ! TRPC3_HUMAN [Term] id: CCO:I0019451 name: mx1-trpc4-1 physical interaction comment: GST pull-down: bait =MxA, prey = TRPC4 ARD domain xref: IntAct:EBI-929536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025166 ! TRPC4_HUMAN relationship: has_participant CCO:B0055123 ! MX1_HUMAN [Term] id: CCO:I0019452 name: mx1-trpc5-1 physical interaction comment: GST pull-down: bait =MxA, prey = TRPC5 ARD domain xref: IntAct:EBI-929568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025167 ! TRPC5_HUMAN relationship: has_participant CCO:B0055123 ! MX1_HUMAN [Term] id: CCO:I0019453 name: mx1-trpc7-7 physical interaction comment: GST pull-down: bait =MxA, prey = TRPC7 ARD domain xref: IntAct:EBI-929592 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0063351 ! TRPC7_HUMAN [Term] id: CCO:I0019454 name: eif4e-4ebp3-2 direct interaction comment: Interaction between eIF4E and 4E-BP3 demonstrated by S-protein pulldown xref: IntAct:EBI-935256 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0054565 ! 4EBP3_HUMAN [Term] id: CCO:I0019455 name: h3_1-jmjd2a colocalization xref: IntAct:EBI-936725 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005221 ! H31_HUMAN relationship: has_participant CCO:B0054610 ! JHD3A_HUMAN [Term] id: CCO:I0019456 name: hdac2-rfx5-2 physical interaction xref: IntAct:EBI-937031 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0055402 ! RFX5_HUMAN [Term] id: CCO:I0019457 name: hdac2-rfx5-3 physical interaction xref: IntAct:EBI-937037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0055402 ! RFX5_HUMAN [Term] id: CCO:I0019458 name: mpzl1-ptpn1-2 physical interaction xref: IntAct:EBI-963407 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054748 ! MPZL1_HUMAN relationship: has_participant CCO:B0055765 ! PTN11_HUMAN [Term] id: CCO:I0019459 name: dicer1-tarbp2-3 physical interaction xref: IntAct:EBI-979298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0062982 ! DICER_HUMAN [Term] id: CCO:I0019460 name: rma1-cftr-1 physical interaction xref: IntAct:EBI-988738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0019461 name: mmp14-adi1-4 colocalization xref: IntAct:EBI-992885 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0032391 ! MTND_HUMAN relationship: has_participant CCO:B0055446 ! MMP14_HUMAN [Term] id: CCO:I0019462 name: setdb1-dnmt3a colocalization xref: IntAct:EBI-995036 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN [Term] id: CCO:I0019463 name: stambp-stam-1 physical interaction xref: IntAct:EBI-996733 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0058093 ! STAM1_HUMAN [Term] id: CCO:I0019464 name: bcl2l2-bid direct interaction xref: IntAct:EBI-1002627 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019465 name: bcl2l1-bik-1 direct interaction xref: IntAct:EBI-1003219 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0019466 name: bcl2l1-hrk direct interaction xref: IntAct:EBI-1003239 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005901 ! BCLX_HUMAN relationship: has_participant CCO:B0054298 ! HRK_HUMAN [Term] id: CCO:I0019467 name: bcl2l1-bbc3 direct interaction xref: IntAct:EBI-1003286 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0019468 name: bcl2l1-bid-1 direct interaction xref: IntAct:EBI-1003344 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN [Term] id: CCO:I0019469 name: bcl2l2-bik direct interaction xref: IntAct:EBI-1003385 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019470 name: bcl2l2-bbc3 direct interaction xref: IntAct:EBI-1003398 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019471 name: mcl1-bid direct interaction xref: IntAct:EBI-1003461 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0055785 ! MCL1_HUMAN [Term] id: CCO:I0019472 name: mcl1-bik direct interaction xref: IntAct:EBI-1003489 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0055785 ! MCL1_HUMAN [Term] id: CCO:I0019473 name: mcl1-bbc3 direct interaction xref: IntAct:EBI-1003527 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0055785 ! MCL1_HUMAN [Term] id: CCO:I0019474 name: bcl2a1-bid direct interaction xref: IntAct:EBI-1003566 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0056148 ! B2LA1_HUMAN [Term] id: CCO:I0019475 name: bcl2a1-bbc3 direct interaction xref: IntAct:EBI-1003593 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0056148 ! B2LA1_HUMAN [Term] id: CCO:I0019476 name: pparg-brg1 physical interaction xref: IntAct:EBI-1008553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005616 ! PPARG_HUMAN [Term] id: CCO:I0019477 name: mmp2-timp2-1 direct interaction comment: Prommp-2-timp-2 complex xref: IntAct:EBI-1033540 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0024617 ! MMP2_HUMAN relationship: has_participant CCO:B0055046 ! TIMP2_HUMAN [Term] id: CCO:I0019478 name: fnta-fntb-13 direct interaction comment: Co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound 33a xref: IntAct:EBI-1036735 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN [Term] id: CCO:I0019479 name: cdr2-morf4l2 direct interaction comment: PCD17 interacts with MRG X in a ligand overlay assay xref: IntAct:EBI-1181557 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0063018 ! CDR2_HUMAN [Term] id: CCO:I0019480 name: spink7-mt2a-3 colocalization comment: ECRG2 and MT2A colocalize in EC109 cells xref: IntAct:EBI-1182786 is_a: CCO:Y0000027 ! colocalization relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0062971 ! ISK7_HUMAN [Term] id: CCO:I0019481 name: nmi-stat4-1 physical interaction comment: Interaction between human Nmi and Stat4 detected by pulldown xref: IntAct:EBI-1186534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0023418 ! STAT4_HUMAN [Term] id: CCO:I0019482 name: stk4-stk4-1 physical interaction comment: Homodimerization of STK4 demonstrated by co-immunoprecipitation xref: IntAct:EBI-367443 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005702 ! STK4_HUMAN [Term] id: CCO:I0019483 name: stk4-stk4-2 physical interaction comment: Homodimerization of STK4 demonstrated by co-immunoprecipitation xref: IntAct:EBI-367451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005702 ! STK4_HUMAN [Term] id: CCO:I0019484 name: wrn-xrcc5-2 physical interaction comment: In vivo Co-IP: bait= WRN, prey = Ku80, ku70, PARP-1 xref: IntAct:EBI-372011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005466 ! KU86_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0019485 name: tceb1-tceb2-4 physical interaction comment: Interaction of Med8 with EloB and EloC. xref: IntAct:EBI-398570 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005491 ! RBX1_HUMAN relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0019486 name: tceb1-tceb2-5 physical interaction comment: Interaction of Med8 with EloB and EloC. xref: IntAct:EBI-398579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005491 ! RBX1_HUMAN relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0019487 name: med8-q9btt4-1 physical interaction comment: Interaction detected by copurification. xref: IntAct:EBI-398607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN [Term] id: CCO:I0019488 name: gga3-tsg101-1 physical interaction comment: two hybrid interaction between GGA3 VHS-GAT fragment and TSG101 xref: IntAct:EBI-447434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0005930 ! GGA3_HUMAN [Term] id: CCO:I0019489 name: eif2b1-adrb2-2 physical interaction comment: Co-IP: bait= human adrenergic receptor beta 2; prey= alpha subunit of initiation factor 2B (eIF-2B) xref: IntAct:EBI-491197 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015682 ! EI2BA_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:I0019490 name: mast2-pclkc-3 physical interaction comment: Interaction of MAST2 and PC-LKC demonstrated by co-immunoprecipitation xref: IntAct:EBI-493835 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056876 ! MAST2_HUMAN relationship: has_participant CCO:B0058577 ! PCD24_HUMAN [Term] id: CCO:I0019491 name: tnfsf10-casp10-2 physical interaction comment: Components of the TRAIL DISC xref: IntAct:EBI-495431 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0019492 name: tnfsf6-casp10-1 physical interaction comment: Components of the Fas DISC xref: IntAct:EBI-495443 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0019493 name: dapk2-dapk2-4 physical interaction comment: Homodimerization of DAPK2 xref: IntAct:EBI-525879 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036525 ! DAPK2_HUMAN [Term] id: CCO:I0019494 name: traf6-tiz-1 physical interaction comment: GST pulldown reveals interaction between the TNF receptor associated factor 6 (TRAF6) protein and the TRAF6-binding zinc finger protein xref: IntAct:EBI-528225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN [Term] id: CCO:I0019495 name: cd40-traf3 physical interaction comment: Yeast-2-hybrid reveals interaction between the CD40 protein and the TNF receptor associated factor 3 (TRAF3) xref: IntAct:EBI-528557 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055188 ! TNR5_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN [Term] id: CCO:I0019496 name: cd27-traf2 physical interaction comment: Yeast-2-hybrid reveals interaction between the tumor necrosis factor receptor superfamily member 7 precursor (CD27) and the TNF receptor associated factor 2 (TRAF2) xref: IntAct:EBI-528882 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN [Term] id: CCO:I0019497 name: snrpa-sfpq-2 physical interaction xref: IntAct:EBI-607098 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0063003 ! SNRPA_HUMAN [Term] id: CCO:I0019498 name: sap18-hdac1-1 physical interaction comment: GST pull-down showing interaction between sap18 and hdac1. xref: IntAct:EBI-620919 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0006113 ! SAP18_HUMAN [Term] id: CCO:I0019499 name: dyrk1b-ranbp9-1 physical interaction comment: Interaction between DYRK1B and RANBP9 identified by Y2H xref: IntAct:EBI-636108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN relationship: has_participant CCO:B0063004 ! RANB9_HUMAN [Term] id: CCO:I0019500 name: irk2-flna-3 physical interaction comment: Co-IP: bait= irk2, prey= filamin A xref: IntAct:EBI-703707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030995 ! IRK2_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN [Term] id: CCO:I0019501 name: hsp1-hsp4-5 physical interaction comment: CoIP: bait = HPS1, prey=HPS4 xref: IntAct:EBI-704445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0019502 name: hsp1-hsp4-6 physical interaction comment: CoIP: bait = HPS4, prey=HPS1 xref: IntAct:EBI-704450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0062978 ! HPS1_HUMAN [Term] id: CCO:I0019503 name: wrn-xrcc5-3 physical interaction comment: Purification of a complex containing WRN, Ku70 and PARP1 (0.4M KCl fraction of SP Sepharose) xref: IntAct:EBI-707088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005467 ! PARP1_HUMAN [Term] id: CCO:I0019504 name: wrn-xrcc5-4 physical interaction comment: Purification of a complex containing WRN and Ku70 (0.15M KCl fraction of SP Sepharose) xref: IntAct:EBI-707096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN [Term] id: CCO:I0019505 name: pmaip1-bclw-2 direct interaction comment: Interaction between Pmaip1 and BCL-w induced by mutation xref: IntAct:EBI-709342 is_a: CCO:Y0000028 ! direct interaction relationship: has_participant CCO:B0006340 ! APR_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN [Term] id: CCO:I0019506 name: nrbp-rac3-1 physical interaction comment: Interaction of NRBP with Rac3 identifed by Y2H xref: IntAct:EBI-767080 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025814 ! RAC3_HUMAN relationship: has_participant CCO:B0062919 ! NRBP_HUMAN [Term] id: CCO:I0019507 name: dapk2-dapk2-1 physical interaction comment: Homodimerization of DAPK2 xref: IntAct:EBI-77170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036525 ! DAPK2_HUMAN [Term] id: CCO:I0019508 name: dapk2-dapk2-2 physical interaction comment: Homodimerization of DAPK2 xref: IntAct:EBI-77180 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0036525 ! DAPK2_HUMAN [Term] id: CCO:I0019509 name: tssk6-hspcb-1 physical interaction comment: Interaction of TSSK6 with HSPCB, HSPA8 and HSPA1A identified by coimmunopreciptiation xref: IntAct:EBI-851898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0063300 ! TSSK6_HUMAN [Term] id: CCO:I0019510 name: pax6-homer3-3 physical interaction comment: Y2H: bait = PAX6 PST domain, prey = HOMER3 xref: IntAct:EBI-851938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0058915 ! HOME3_HUMAN [Term] id: CCO:I0019511 name: pax6-trim11-2 physical interaction comment: Y2H: bait = PAX6 PST domain, prey = Trim11 xref: IntAct:EBI-851951 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0063350 ! TRI11_HUMAN [Term] id: CCO:I0019512 name: mycn-max-2 physical interaction comment: Interaction between human MycN and MAX detected by beta galactosidase assay xref: IntAct:EBI-878426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005336 ! MAX_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:I0019513 name: mycn-nmi-2 physical interaction comment: Interaction between human MycN and Nmi detected by beta galactosidase assay xref: IntAct:EBI-878443 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN [Term] id: CCO:I0019514 name: grem1-14_3_3 eta-2 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the Gremlin 1 protein and YWHAH protein xref: IntAct:EBI-914607 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0063191 ! GREM1_HUMAN [Term] id: CCO:I0019515 name: 14_3_3 eta-grem1-1 physical interaction comment: Coimmunoprecipitation analysis reveals interaction between the YWHAH protein and Gremlin 1 protein xref: IntAct:EBI-914614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0063191 ! GREM1_HUMAN [Term] id: CCO:I0019516 name: pxn-rnf5-4 physical interaction xref: IntAct:EBI-963460 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0043430 ! RNF5_HUMAN [Term] id: CCO:I0019517 name: ikbkb-nfkbia-3 phosphorylation comment: Phosphorylation of I-kappa B alpha by I-kappa kinase beta xref: IntAct:EBI-985800 is_a: CCO:Y0000024 ! phosphorylation reaction relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN [Term] id: CCO:I0019518 name: ldlr-hsp90b1 physical interaction xref: IntAct:EBI-988358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055025 ! ENPL_HUMAN relationship: has_participant CCO:B0063373 ! LDLR_HUMAN [Term] id: CCO:I0019519 name: pscd2-atp6v0a2-7 physical interaction comment: Interaction between Pscd2 and Atp6v0a2 demonstrated by coimmunoprecipitation xref: IntAct:EBI-988653 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058410 ! CYH2_HUMAN relationship: has_participant CCO:B0063303 ! VPP2_HUMAN [Term] id: CCO:I0019520 name: arf6-atp6v1c1-4 physical interaction comment: Interaction between Arf6 and Atp6v1c1 demonstrated by coimmunoprecipitation xref: IntAct:EBI-988729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055616 ! ARF6_HUMAN relationship: has_participant CCO:B0063235 ! VATC1_HUMAN [Term] id: CCO:I0019521 name: mbde-cbx5-1 physical interaction xref: IntAct:EBI-994667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0019522 name: mbde-hdac1-1 physical interaction xref: IntAct:EBI-994769 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0019523 name: mbde-hdac2-1 physical interaction xref: IntAct:EBI-994784 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN [Term] id: CCO:I0019524 name: eef1d-eef1g physical interaction xref: IntAct:EBI-728414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:I0019525 name: eef1g-eef1d physical interaction xref: IntAct:EBI-728417 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:I0019526 name: arpc5l-arpc4 physical interaction xref: IntAct:EBI-728435 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058471 ! ARP5L_HUMAN relationship: has_participant CCO:B0063364 ! ARPC4_HUMAN [Term] id: CCO:I0019527 name: ascc2-eef1d physical interaction xref: IntAct:EBI-728438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:I0019528 name: ascc2-rplp1 physical interaction xref: IntAct:EBI-728441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005770 ! RLA1_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:I0019529 name: ascc2-snw1 physical interaction xref: IntAct:EBI-728444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0048570 ! Q6I9S2_HUMAN [Term] id: CCO:I0019530 name: ccl18-eef1a1 physical interaction xref: IntAct:EBI-728459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006087 ! CCL18_HUMAN [Term] id: CCO:I0019531 name: cdc42-eef1g physical interaction xref: IntAct:EBI-728465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0019532 name: cdc42-unc119 physical interaction xref: IntAct:EBI-728468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019533 name: cdk5rap2-eef1g physical interaction xref: IntAct:EBI-728474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:I0019534 name: cpe-med31 physical interaction xref: IntAct:EBI-728489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006081 ! CBPE_HUMAN [Term] id: CCO:I0019535 name: cstf2-chd3 physical interaction xref: IntAct:EBI-728495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063344 ! CSTF2_HUMAN [Term] id: CCO:I0019536 name: fubp1-tle1 physical interaction xref: IntAct:EBI-728522 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:I0019537 name: hspe1-c14orf1 physical interaction xref: IntAct:EBI-728531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006092 ! CH10_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019538 name: hspe1-eef1a1 physical interaction xref: IntAct:EBI-728534 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006092 ! CH10_HUMAN [Term] id: CCO:I0019539 name: lama4-eef1a1 physical interaction xref: IntAct:EBI-728540 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN [Term] id: CCO:I0019540 name: rnpc4-med31 physical interaction xref: IntAct:EBI-728588 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006106 ! Q6IA98_HUMAN [Term] id: CCO:I0019541 name: rpa2-med31 physical interaction xref: IntAct:EBI-728594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0019542 name: rpa2-crmp1 physical interaction xref: IntAct:EBI-728597 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0019543 name: rpa2-eef1a1 physical interaction xref: IntAct:EBI-728600 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0019544 name: rpa2-kiaa1377 physical interaction xref: IntAct:EBI-728606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN [Term] id: CCO:I0019545 name: rpa2-utp14a physical interaction xref: IntAct:EBI-728612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0019546 name: rpa2-tle1 physical interaction xref: IntAct:EBI-728615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0019547 name: rps3a-hspca physical interaction xref: IntAct:EBI-728630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN [Term] id: CCO:I0019548 name: sat-tle1 physical interaction xref: IntAct:EBI-728639 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019549 name: selenbp1-med31 physical interaction xref: IntAct:EBI-728642 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006083 ! SBP1_HUMAN [Term] id: CCO:I0019550 name: serpinb9-crmp1 physical interaction xref: IntAct:EBI-728651 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0019551 name: serpinb9-eef1a1 physical interaction xref: IntAct:EBI-728654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0019552 name: sumo2-chd3 physical interaction xref: IntAct:EBI-728660 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0019553 name: tp53i3-unc119 physical interaction xref: IntAct:EBI-728666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043869 ! U119A_HUMAN relationship: has_participant CCO:B0056356 ! QORX_HUMAN [Term] id: CCO:I0019554 name: zfp64-tle1 physical interaction xref: IntAct:EBI-728672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0037139 ! ZF64A_HUMAN [Term] id: CCO:I0019555 name: znf24-crmp1 physical interaction xref: IntAct:EBI-728675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0019556 name: znf24-eef1a1 physical interaction xref: IntAct:EBI-728678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0019557 name: znf24-eef1g physical interaction xref: IntAct:EBI-728681 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0019558 name: actg1-pfn2 physical interaction xref: IntAct:EBI-728687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0019559 name: arf4l-eif2b1 physical interaction xref: IntAct:EBI-728705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN relationship: has_participant CCO:B0015682 ! EI2BA_HUMAN [Term] id: CCO:I0019560 name: arf4l-tle1 physical interaction xref: IntAct:EBI-728708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN [Term] id: CCO:I0019561 name: arf4l-ubr1 physical interaction xref: IntAct:EBI-728711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006135 ! UBR1_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN [Term] id: CCO:I0019562 name: arf4l-unc119 physical interaction xref: IntAct:EBI-728714 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019563 name: arpc3-bat3 physical interaction xref: IntAct:EBI-728738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN [Term] id: CCO:I0019564 name: ascc2-med31 physical interaction xref: IntAct:EBI-728741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:I0019565 name: atp5c1-mpp1 physical interaction xref: IntAct:EBI-728748 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006122 ! ATPG_HUMAN relationship: has_participant CCO:B0019045 ! EM55_HUMAN [Term] id: CCO:I0019566 name: bat3-ikbkap physical interaction xref: IntAct:EBI-728760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:I0019567 name: bat3-setdb1 physical interaction xref: IntAct:EBI-728763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006127 ! BAT3_HUMAN [Term] id: CCO:I0019568 name: bhlhb2-chd3 physical interaction xref: IntAct:EBI-728766 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0019569 name: bhlhb2-zhx1 physical interaction xref: IntAct:EBI-728769 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN [Term] id: CCO:I0019570 name: btbd2-tle1 physical interaction xref: IntAct:EBI-728778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005933 ! BTBD2_HUMAN [Term] id: CCO:I0019571 name: trib3-dkfzp564o0523 physical interaction xref: IntAct:EBI-728793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019572 name: trib3-eef1g physical interaction xref: IntAct:EBI-728796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0019573 name: trib3-htatip physical interaction xref: IntAct:EBI-728799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN [Term] id: CCO:I0019574 name: ccl18-crmp1 physical interaction xref: IntAct:EBI-728808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0006087 ! CCL18_HUMAN [Term] id: CCO:I0019575 name: ccl18-unc119 physical interaction xref: IntAct:EBI-728814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006087 ! CCL18_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019576 name: cdk5rap2-crmp1 physical interaction xref: IntAct:EBI-728829 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:I0019577 name: cdk5rap2-dkfzp564o05 physical interaction xref: IntAct:EBI-728832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019578 name: cpe-utp14a physical interaction xref: IntAct:EBI-728850 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006081 ! CBPE_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0019579 name: creb1-chd3 physical interaction xref: IntAct:EBI-728862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0019580 name: ddr1-snapap physical interaction xref: IntAct:EBI-728871 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006158 ! DDR1_HUMAN relationship: has_participant CCO:B0043870 ! SNAPN_HUMAN [Term] id: CCO:I0019581 name: ddr1-ttr physical interaction xref: IntAct:EBI-728874 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006158 ! DDR1_HUMAN relationship: has_participant CCO:B0063374 ! TTHY_HUMAN [Term] id: CCO:I0019582 name: dlst-zhx1 physical interaction xref: IntAct:EBI-728880 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006185 ! ODO2_HUMAN [Term] id: CCO:I0019583 name: dncl1-eef1a1 physical interaction xref: IntAct:EBI-728886 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006226 ! DYL1_HUMAN [Term] id: CCO:I0019584 name: dnmt2-unc119 physical interaction xref: IntAct:EBI-728889 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019585 name: eef1a1-pfn2 physical interaction xref: IntAct:EBI-728895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0019586 name: eef1d-crmp1 physical interaction xref: IntAct:EBI-728898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:I0019587 name: eef1g-med31 physical interaction xref: IntAct:EBI-728901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006079 ! EF1G_HUMAN [Term] id: CCO:I0019588 name: eif2s2-tle1 physical interaction xref: IntAct:EBI-728916 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006090 ! IF2B_HUMAN [Term] id: CCO:I0019589 name: eif3s5-eef1a1 physical interaction xref: IntAct:EBI-728925 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0026277 ! EIF3F_HUMAN [Term] id: CCO:I0019590 name: fubp1-chd3 physical interaction xref: IntAct:EBI-728934 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:I0019591 name: fubp1-vim physical interaction xref: IntAct:EBI-728937 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:I0019592 name: hnrph3-htatip physical interaction xref: IntAct:EBI-728967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006277 ! HNRH3_HUMAN [Term] id: CCO:I0019593 name: hspe1-crmp1 physical interaction xref: IntAct:EBI-728976 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0006092 ! CH10_HUMAN [Term] id: CCO:I0019594 name: hspe1-tle1 physical interaction xref: IntAct:EBI-728982 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006092 ! CH10_HUMAN [Term] id: CCO:I0019595 name: hspe1-unc119 physical interaction xref: IntAct:EBI-728985 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006092 ! CH10_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019596 name: itgb3bp-aldh2 physical interaction xref: IntAct:EBI-728991 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063375 ! ALDH2_HUMAN [Term] id: CCO:I0019597 name: itgb3bp-kiaa1377 physical interaction xref: IntAct:EBI-728994 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:I0019598 name: lama4-med31 physical interaction xref: IntAct:EBI-729009 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN [Term] id: CCO:I0019599 name: lama4-unc119 physical interaction xref: IntAct:EBI-729024 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019600 name: loc51236-med31 physical interaction xref: IntAct:EBI-729030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006094 ! Q96BK8_HUMAN [Term] id: CCO:I0019601 name: lsm3-gdf9 physical interaction xref: IntAct:EBI-729045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005566 ! LSM3_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0019602 name: rsrc1-gdf9 physical interaction xref: IntAct:EBI-729054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0063376 ! RSRC1_HUMAN [Term] id: CCO:I0019603 name: np-aplp1 physical interaction xref: IntAct:EBI-729078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006097 ! PNPH_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019604 name: pafah1b3-med31 physical interaction xref: IntAct:EBI-729090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN [Term] id: CCO:I0019605 name: pafah1b3-tle1 physical interaction xref: IntAct:EBI-729102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN [Term] id: CCO:I0019606 name: pcdha4-tle1 physical interaction xref: IntAct:EBI-729120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006099 ! PCDA4_HUMAN [Term] id: CCO:I0019607 name: pdcd5-eef1g physical interaction xref: IntAct:EBI-729129 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0006152 ! PDCD5_HUMAN [Term] id: CCO:I0019608 name: polr3f-c14orf1 physical interaction xref: IntAct:EBI-729135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006101 ! RPC6_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019609 name: psmd11-med31 physical interaction xref: IntAct:EBI-729153 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0019610 name: psmd11-tle1 physical interaction xref: IntAct:EBI-729168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0019611 name: rfc5-unc119 physical interaction xref: IntAct:EBI-729216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019612 name: rpa2-rplp1 physical interaction xref: IntAct:EBI-729225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:I0019613 name: rpa2-unc119 physical interaction xref: IntAct:EBI-729228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019614 name: rxrg-ppara physical interaction xref: IntAct:EBI-729240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024881 ! RXRG_HUMAN relationship: has_participant CCO:B0055786 ! PPARA_HUMAN [Term] id: CCO:I0019615 name: sat-hspe1 physical interaction xref: IntAct:EBI-729252 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006092 ! CH10_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019616 name: sat-htatip physical interaction xref: IntAct:EBI-729255 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019617 name: serpinb9-med31 physical interaction xref: IntAct:EBI-729273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0019618 name: serpinb9-dkfzp564o05 physical interaction xref: IntAct:EBI-729276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019619 name: serpinb9-tle1 physical interaction xref: IntAct:EBI-729285 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0019620 name: serpinb9-ubr1 physical interaction xref: IntAct:EBI-729294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:I0019621 name: serpinb9-unc119 physical interaction xref: IntAct:EBI-729297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019622 name: sgta-pfn2 physical interaction xref: IntAct:EBI-729300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006084 ! SGTA_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0019623 name: sirt6-chd3 physical interaction xref: IntAct:EBI-729309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0057492 ! SIRT6_HUMAN [Term] id: CCO:I0019624 name: slc25a6-chd3 physical interaction xref: IntAct:EBI-729318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0019625 name: snap25-stx1a physical interaction xref: IntAct:EBI-729330 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055598 ! SNP25_HUMAN relationship: has_participant CCO:B0056163 ! STX1A_HUMAN [Term] id: CCO:I0019626 name: stx1a-snap25 physical interaction xref: IntAct:EBI-729333 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055598 ! SNP25_HUMAN relationship: has_participant CCO:B0056163 ! STX1A_HUMAN [Term] id: CCO:I0019627 name: snapap-ikbkap physical interaction xref: IntAct:EBI-729336 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0043870 ! SNAPN_HUMAN [Term] id: CCO:I0019628 name: taf9-eef1a1 physical interaction xref: IntAct:EBI-729360 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0005938 ! TAF9_HUMAN [Term] id: CCO:I0019629 name: timp1-ech1 physical interaction xref: IntAct:EBI-729363 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054831 ! TIMP1_HUMAN relationship: has_participant CCO:B0063377 ! ECH1_HUMAN [Term] id: CCO:I0019630 name: timp1-eef1b2 physical interaction xref: IntAct:EBI-729366 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005752 ! EF1B_HUMAN relationship: has_participant CCO:B0054831 ! TIMP1_HUMAN [Term] id: CCO:I0019631 name: timp1-sumo2 physical interaction xref: IntAct:EBI-729369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054831 ! TIMP1_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0019632 name: tk1-crmp1 physical interaction xref: IntAct:EBI-729372 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0006114 ! KITH_HUMAN [Term] id: CCO:I0019633 name: tk1-tle1 physical interaction xref: IntAct:EBI-729381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006114 ! KITH_HUMAN [Term] id: CCO:I0019634 name: tk1-unc119 physical interaction xref: IntAct:EBI-729387 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019635 name: tmsb4x-unc119 physical interaction xref: IntAct:EBI-729396 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006115 ! TYB4_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019636 name: tnfrsf6-crmp1 physical interaction xref: IntAct:EBI-729399 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0019637 name: ttr-ikbkap physical interaction xref: IntAct:EBI-729414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0063374 ! TTHY_HUMAN [Term] id: CCO:I0019638 name: ywhaz-kiaa1377 physical interaction xref: IntAct:EBI-729438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0019639 name: znf24-dkfzp564o0523 physical interaction xref: IntAct:EBI-729441 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019640 name: znf24-htatip physical interaction xref: IntAct:EBI-729444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0019641 name: znf24-kiaa1377 physical interaction xref: IntAct:EBI-729447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0019642 name: znf24-unc119 physical interaction xref: IntAct:EBI-729453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019643 name: actg1-sh3gl2 physical interaction xref: IntAct:EBI-729459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0019644 name: actn2-tuba1 physical interaction xref: IntAct:EBI-729462 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005449 ! TBA4A_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN [Term] id: CCO:I0019645 name: agr2-med31 physical interaction xref: IntAct:EBI-729465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0033164 ! AGR2_HUMAN [Term] id: CCO:I0019646 name: anxa3-ubr1 physical interaction xref: IntAct:EBI-729486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006119 ! ANXA3_HUMAN relationship: has_participant CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:I0019647 name: anxa3-unc119 physical interaction xref: IntAct:EBI-729489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006119 ! ANXA3_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019648 name: aof2-gdf9 physical interaction xref: IntAct:EBI-729492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005589 ! LSD1_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0019649 name: arf1-eef1g physical interaction xref: IntAct:EBI-729507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0015288 ! ARF1_HUMAN [Term] id: CCO:I0019650 name: arf4l-snrpn physical interaction xref: IntAct:EBI-729510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006111 ! RSMN_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN [Term] id: CCO:I0019651 name: arhgdia-fen1 physical interaction xref: IntAct:EBI-729528 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0019652 name: arih2-htatip physical interaction xref: IntAct:EBI-729537 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005288 ! ARI2_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:I0019653 name: arl3-pde6d physical interaction xref: IntAct:EBI-729546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006120 ! ARL3_HUMAN relationship: has_participant CCO:B0006130 ! PDE6D_HUMAN [Term] id: CCO:I0019654 name: arl3-tle1 physical interaction xref: IntAct:EBI-729552 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006120 ! ARL3_HUMAN [Term] id: CCO:I0019655 name: arl3-ubr1 physical interaction xref: IntAct:EBI-729558 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006120 ! ARL3_HUMAN relationship: has_participant CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:I0019656 name: arl3-unc119 physical interaction xref: IntAct:EBI-729561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006120 ! ARL3_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019657 name: ars2-chd3 physical interaction xref: IntAct:EBI-729564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:I0019658 name: ars2-git1 physical interaction xref: IntAct:EBI-729567 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0050587 ! ARS2_HUMAN [Term] id: CCO:I0019659 name: ascc2-aof2 physical interaction xref: IntAct:EBI-729573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005589 ! LSD1_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:I0019660 name: ascc2-ass physical interaction xref: IntAct:EBI-729576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0063252 ! ASSY_HUMAN [Term] id: CCO:I0019661 name: ascc2-fbp1 physical interaction xref: IntAct:EBI-729579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0043610 ! F16P1_HUMAN [Term] id: CCO:I0019662 name: ascc2-pola2 physical interaction xref: IntAct:EBI-729582 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:I0019663 name: ascc2-ptd004 physical interaction xref: IntAct:EBI-729585 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0006293 ! Q53SQ6_HUMAN [Term] id: CCO:I0019664 name: atp5c1-pola2 physical interaction xref: IntAct:EBI-729594 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:I0019665 name: atp6v1e1-g22p1 physical interaction xref: IntAct:EBI-729606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0021842 ! VATE1_HUMAN [Term] id: CCO:I0019666 name: bcar1-hspa5 physical interaction xref: IntAct:EBI-729615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005843 ! GRP78_HUMAN [Term] id: CCO:I0019667 name: bcr-unc119 physical interaction xref: IntAct:EBI-729621 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006123 ! BCR_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019668 name: bhlhb2-setdb1 physical interaction xref: IntAct:EBI-729627 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN [Term] id: CCO:I0019669 name: bhlhb2-vim physical interaction xref: IntAct:EBI-729630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN [Term] id: CCO:I0019670 name: bmi1-htatip physical interaction xref: IntAct:EBI-729633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006124 ! Q5T8Z1_HUMAN [Term] id: CCO:I0019671 name: btbd2-setdb1 physical interaction xref: IntAct:EBI-729645 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005933 ! BTBD2_HUMAN [Term] id: CCO:I0019672 name: c14orf139-sqstm1 physical interaction xref: IntAct:EBI-729657 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN relationship: has_participant CCO:B0063378 ! CN139_HUMAN [Term] id: CCO:I0019673 name: ubqln4-rxra physical interaction xref: IntAct:EBI-729663 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005619 ! UBQL4_HUMAN relationship: has_participant CCO:B0024886 ! RXRA_HUMAN [Term] id: CCO:I0019674 name: trib3-cops6 physical interaction xref: IntAct:EBI-729666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0019675 name: trib3-gdf9 physical interaction xref: IntAct:EBI-729669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0019676 name: trib3-git1 physical interaction xref: IntAct:EBI-729672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN [Term] id: CCO:I0019677 name: trib3-setdb1 physical interaction xref: IntAct:EBI-729675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN [Term] id: CCO:I0019678 name: c2orf17-chd3 physical interaction xref: IntAct:EBI-729678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063379 ! F134A_HUMAN [Term] id: CCO:I0019679 name: c7orf20-htatip physical interaction xref: IntAct:EBI-729684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006174 ! CG020_HUMAN [Term] id: CCO:I0019680 name: c7orf36-chd3 physical interaction xref: IntAct:EBI-729687 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006249 ! CG036_HUMAN [Term] id: CCO:I0019681 name: casp8-vim physical interaction xref: IntAct:EBI-729696 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0019682 name: cbx8-eef1g physical interaction xref: IntAct:EBI-729702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:I0019683 name: cbx8-htatip physical interaction xref: IntAct:EBI-729705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:I0019684 name: cbx8-myst2 physical interaction xref: IntAct:EBI-729708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:I0019685 name: cbx8-unc119 physical interaction xref: IntAct:EBI-729711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043869 ! U119A_HUMAN relationship: has_participant CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:I0019686 name: ccl18-tle1 physical interaction xref: IntAct:EBI-729714 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006087 ! CCL18_HUMAN [Term] id: CCO:I0019687 name: cct5-ikbkap physical interaction xref: IntAct:EBI-729717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005291 ! TCPE_HUMAN relationship: has_participant CCO:B0005398 ! ELP1_HUMAN [Term] id: CCO:I0019688 name: cdc42-c14orf1 physical interaction xref: IntAct:EBI-729735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019689 name: cdc42-pde6d physical interaction xref: IntAct:EBI-729738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0006130 ! PDE6D_HUMAN [Term] id: CCO:I0019690 name: cdc42-ubr1 physical interaction xref: IntAct:EBI-729741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:I0019691 name: cdk5rap2-c14orf1 physical interaction xref: IntAct:EBI-729750 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019692 name: cdk5rap2-hap1 physical interaction xref: IntAct:EBI-729753 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:I0019693 name: cdk5rap2-htatip physical interaction xref: IntAct:EBI-729756 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:I0019694 name: cdk5rap2-luc7l2 physical interaction xref: IntAct:EBI-729759 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:I0019695 name: chd3-immt physical interaction xref: IntAct:EBI-729789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:I0019696 name: cpe-poldip2 physical interaction xref: IntAct:EBI-729810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006081 ! CBPE_HUMAN relationship: has_participant CCO:B0063380 ! PDIP2_HUMAN [Term] id: CCO:I0019697 name: creb1-vim physical interaction xref: IntAct:EBI-729813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0019698 name: creld1-gdf9 physical interaction xref: IntAct:EBI-729822 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006132 ! CREL1_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0019699 name: creld1-setdb1 physical interaction xref: IntAct:EBI-729831 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006132 ! CREL1_HUMAN [Term] id: CCO:I0019700 name: csnk2a1-zhx1 physical interaction xref: IntAct:EBI-729834 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005428 ! CSK21_HUMAN [Term] id: CCO:I0019701 name: cstf2-htatip physical interaction xref: IntAct:EBI-729840 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063344 ! CSTF2_HUMAN [Term] id: CCO:I0019702 name: cstf2-ikbkap physical interaction xref: IntAct:EBI-729843 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0063344 ! CSTF2_HUMAN [Term] id: CCO:I0019703 name: cugbp1-tom1l1 physical interaction xref: IntAct:EBI-729849 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006203 ! TM1L1_HUMAN relationship: has_participant CCO:B0006265 ! CELF1_HUMAN [Term] id: CCO:I0019704 name: ddx24-git1 physical interaction xref: IntAct:EBI-729855 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:I0019705 name: ddx24-pola2 physical interaction xref: IntAct:EBI-729858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:I0019706 name: dncl1-c14orf1 physical interaction xref: IntAct:EBI-729903 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006226 ! DYL1_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019707 name: dncl1-zhx1 physical interaction xref: IntAct:EBI-729906 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006226 ! DYL1_HUMAN [Term] id: CCO:I0019708 name: dnmt2-eef1a1 physical interaction xref: IntAct:EBI-729912 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN [Term] id: CCO:I0019709 name: dnmt2-setdb1 physical interaction xref: IntAct:EBI-729918 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN [Term] id: CCO:I0019710 name: eef1d-eef1d physical interaction xref: IntAct:EBI-729924 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021069 ! EF1D_HUMAN [Term] id: CCO:I0019711 name: egr2-med31 physical interaction xref: IntAct:EBI-729927 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006070 ! EGR2_HUMAN [Term] id: CCO:I0019712 name: eif2s2-aplp1 physical interaction xref: IntAct:EBI-729930 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006090 ! IF2B_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019713 name: epn1-med31 physical interaction xref: IntAct:EBI-729948 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0063381 ! EPN1_HUMAN [Term] id: CCO:I0019714 name: ezh2-pola2 physical interaction xref: IntAct:EBI-729966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0043441 ! EZH2_HUMAN [Term] id: CCO:I0019715 name: fen1-eef1g physical interaction xref: IntAct:EBI-729972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN [Term] id: CCO:I0019716 name: fgfr3-kiaa1377 physical interaction xref: IntAct:EBI-729975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0019717 name: fgfr3-rpl8 physical interaction xref: IntAct:EBI-729978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005860 ! RL8_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0019718 name: fgfr3-slc25a6 physical interaction xref: IntAct:EBI-729981 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0019719 name: flj20487-ikbkap physical interaction xref: IntAct:EBI-729999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0025227 ! EMI5_HUMAN [Term] id: CCO:I0019720 name: fth1-crmp1 physical interaction xref: IntAct:EBI-730015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0033704 ! FRIH_HUMAN [Term] id: CCO:I0019721 name: fth1-ubr1 physical interaction xref: IntAct:EBI-730018 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006135 ! UBR1_HUMAN relationship: has_participant CCO:B0033704 ! FRIH_HUMAN [Term] id: CCO:I0019722 name: fts-pola2 physical interaction xref: IntAct:EBI-730030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0026276 ! AKTIP_HUMAN [Term] id: CCO:I0019723 name: fubp1-crmp1 physical interaction xref: IntAct:EBI-730033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:I0019724 name: fxyd6-tle1 physical interaction xref: IntAct:EBI-730045 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006141 ! FXYD6_HUMAN [Term] id: CCO:I0019725 name: golph2-fth1 physical interaction xref: IntAct:EBI-730066 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006331 ! GOLM1_HUMAN relationship: has_participant CCO:B0033704 ! FRIH_HUMAN [Term] id: CCO:I0019726 name: gstm4-tle1 physical interaction xref: IntAct:EBI-730081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006144 ! GSTM4_HUMAN [Term] id: CCO:I0019727 name: gsto1-htatip physical interaction xref: IntAct:EBI-730090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0036172 ! GSTO1_HUMAN [Term] id: CCO:I0019728 name: gsto1-setdb1 physical interaction xref: IntAct:EBI-730093 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0036172 ! GSTO1_HUMAN [Term] id: CCO:I0019729 name: hbxip-eef1a1 physical interaction xref: IntAct:EBI-730102 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:I0019730 name: hbxip-git1 physical interaction xref: IntAct:EBI-730108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:I0019731 name: hbxip-kiaa1377 physical interaction xref: IntAct:EBI-730111 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:I0019732 name: hla_dqa1-tle1 physical interaction xref: IntAct:EBI-730120 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006147 ! HA23_HUMAN [Term] id: CCO:I0019733 name: hmgb1-unc119 physical interaction xref: IntAct:EBI-730132 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019734 name: hmox2-med31 physical interaction xref: IntAct:EBI-730135 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006148 ! HMOX2_HUMAN [Term] id: CCO:I0019735 name: hmox2-git1 physical interaction xref: IntAct:EBI-730138 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0006148 ! HMOX2_HUMAN [Term] id: CCO:I0019736 name: hnrpr-hrmt1l2 physical interaction xref: IntAct:EBI-730150 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0063382 ! HNRPR_HUMAN [Term] id: CCO:I0019737 name: hrmt1l2-med31 physical interaction xref: IntAct:EBI-730165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN [Term] id: CCO:I0019738 name: hrmt1l2-hrmt1l2 physical interaction xref: IntAct:EBI-730168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN [Term] id: CCO:I0019739 name: hspb1-med31 physical interaction xref: IntAct:EBI-730180 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN [Term] id: CCO:I0019740 name: hspb1-dkfzp564o0523 physical interaction xref: IntAct:EBI-730183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019741 name: hspe1-aplp1 physical interaction xref: IntAct:EBI-730195 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006092 ! CH10_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019742 name: hspe1-zhx1 physical interaction xref: IntAct:EBI-730198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006092 ! CH10_HUMAN [Term] id: CCO:I0019743 name: id2-unc119 physical interaction xref: IntAct:EBI-730210 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006149 ! ID2_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019744 name: ik-chd3 physical interaction xref: IntAct:EBI-730213 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006239 ! RED_HUMAN [Term] id: CCO:I0019745 name: ik-htatip physical interaction xref: IntAct:EBI-730216 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006239 ! RED_HUMAN [Term] id: CCO:I0019746 name: itgb3bp-actg1 physical interaction xref: IntAct:EBI-730219 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0015628 ! ACTG_HUMAN [Term] id: CCO:I0019747 name: itgb3bp-flj10094 physical interaction xref: IntAct:EBI-730222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0062800 ! ENOX1_HUMAN [Term] id: CCO:I0019748 name: itgb3bp-git1 physical interaction xref: IntAct:EBI-730225 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:I0019749 name: itgb3bp-hip1 physical interaction xref: IntAct:EBI-730228 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0006214 ! HIP1_HUMAN [Term] id: CCO:I0019750 name: itgb3bp-pola2 physical interaction xref: IntAct:EBI-730231 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:I0019751 name: itsn1-eef1a1 physical interaction xref: IntAct:EBI-730234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0019752 name: itsn1-kif5a physical interaction xref: IntAct:EBI-730237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006166 ! KIF5A_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0019753 name: itsn1-unc119 physical interaction xref: IntAct:EBI-730240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019754 name: lama4-cops6 physical interaction xref: IntAct:EBI-730249 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0019755 name: lama4-ubr1 physical interaction xref: IntAct:EBI-730255 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN relationship: has_participant CCO:B0006135 ! UBR1_HUMAN [Term] id: CCO:I0019756 name: lama4-zhx1 physical interaction xref: IntAct:EBI-730258 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN [Term] id: CCO:I0019757 name: lmna-htatip physical interaction xref: IntAct:EBI-730261 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0062989 ! LMNA_HUMAN [Term] id: CCO:I0019758 name: luc7l2-chd3 physical interaction xref: IntAct:EBI-730273 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:I0019759 name: lyar-zhx1 physical interaction xref: IntAct:EBI-730282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0063383 ! LYAR_HUMAN [Term] id: CCO:I0019760 name: mafg-chd3 physical interaction xref: IntAct:EBI-730300 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0042178 ! MAFG_HUMAN [Term] id: CCO:I0019761 name: man2a2-chd3 physical interaction xref: IntAct:EBI-730303 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063384 ! MA2A2_HUMAN [Term] id: CCO:I0019762 name: map1lc3b-sqstm1 physical interaction xref: IntAct:EBI-730315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006342 ! MLP3B_HUMAN relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:I0019763 name: mapk10-gtf3c1 physical interaction xref: IntAct:EBI-730318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN relationship: has_participant CCO:B0026768 ! MK10_HUMAN [Term] id: CCO:I0019764 name: mapk10-unc119 physical interaction xref: IntAct:EBI-730321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026768 ! MK10_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019765 name: mapk9-kiaa1377 physical interaction xref: IntAct:EBI-730324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0026769 ! MK09_HUMAN [Term] id: CCO:I0019766 name: c16orf24-htatip physical interaction xref: IntAct:EBI-730333 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0061994 ! F173A_HUMAN [Term] id: CCO:I0019767 name: mrpl12-mrpl12 physical interaction xref: IntAct:EBI-730348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055501 ! RM12_HUMAN [Term] id: CCO:I0019768 name: mrpl44-setdb1 physical interaction xref: IntAct:EBI-730354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063385 ! RM44_HUMAN [Term] id: CCO:I0019769 name: naca-zhx1 physical interaction xref: IntAct:EBI-730375 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006096 ! NACA_HUMAN [Term] id: CCO:I0019770 name: nap1l5-htatip physical interaction xref: IntAct:EBI-730378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063386 ! NP1L5_HUMAN [Term] id: CCO:I0019771 name: nck2-eef1g physical interaction xref: IntAct:EBI-730381 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:I0019772 name: np-zhx1 physical interaction xref: IntAct:EBI-730411 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006097 ! PNPH_HUMAN [Term] id: CCO:I0019773 name: paep-g22p1 physical interaction xref: IntAct:EBI-730432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0006212 ! PAEP_HUMAN [Term] id: CCO:I0019774 name: pafah1b3-g22p1 physical interaction xref: IntAct:EBI-730444 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN [Term] id: CCO:I0019775 name: pafah1b3-setdb1 physical interaction xref: IntAct:EBI-730447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN [Term] id: CCO:I0019776 name: pafah1b3-zhx1 physical interaction xref: IntAct:EBI-730450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN [Term] id: CCO:I0019777 name: paics-chd3 physical interaction xref: IntAct:EBI-730456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063387 ! PUR6_HUMAN [Term] id: CCO:I0019778 name: rp11_102m16_2-chd3 physical interaction xref: IntAct:EBI-730459 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0037759 ! Q5VU21_HUMAN [Term] id: CCO:I0019779 name: pak4-dlst physical interaction xref: IntAct:EBI-730465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006185 ! ODO2_HUMAN relationship: has_participant CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:I0019780 name: pcdha4-aplp1 physical interaction xref: IntAct:EBI-730474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006099 ! PCDA4_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019781 name: pcdha4-setdb1 physical interaction xref: IntAct:EBI-730486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006099 ! PCDA4_HUMAN [Term] id: CCO:I0019782 name: pdcd5-htatip physical interaction xref: IntAct:EBI-730489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006152 ! PDCD5_HUMAN [Term] id: CCO:I0019783 name: pdcd5-kiaa1377 physical interaction xref: IntAct:EBI-730492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0006152 ! PDCD5_HUMAN [Term] id: CCO:I0019784 name: pdcd5-utp14a physical interaction xref: IntAct:EBI-730498 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0006152 ! PDCD5_HUMAN [Term] id: CCO:I0019785 name: pfn1-crmp1 physical interaction xref: IntAct:EBI-730519 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0006154 ! PROF1_HUMAN [Term] id: CCO:I0019786 name: pfn1-unc119 physical interaction xref: IntAct:EBI-730525 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006154 ! PROF1_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019787 name: polb-myst2 physical interaction xref: IntAct:EBI-730540 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0054905 ! DPOLB_HUMAN [Term] id: CCO:I0019788 name: pole2-c14orf1 physical interaction xref: IntAct:EBI-730543 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019789 name: pole2-eef1a1 physical interaction xref: IntAct:EBI-730546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN [Term] id: CCO:I0019790 name: pole2-htatip physical interaction xref: IntAct:EBI-730549 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN [Term] id: CCO:I0019791 name: pole2-tle1 physical interaction xref: IntAct:EBI-730552 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN [Term] id: CCO:I0019792 name: polr2c-smarcc2 physical interaction xref: IntAct:EBI-730561 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0006100 ! RPB3_HUMAN [Term] id: CCO:I0019793 name: polr2c-stc2 physical interaction xref: IntAct:EBI-730564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006100 ! RPB3_HUMAN relationship: has_participant CCO:B0006237 ! STC2_HUMAN [Term] id: CCO:I0019794 name: polr3f-htatip physical interaction xref: IntAct:EBI-730567 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006101 ! RPC6_HUMAN [Term] id: CCO:I0019795 name: polr3f-stc2 physical interaction xref: IntAct:EBI-730570 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006101 ! RPC6_HUMAN relationship: has_participant CCO:B0006237 ! STC2_HUMAN [Term] id: CCO:I0019796 name: pp-setdb1 physical interaction xref: IntAct:EBI-730573 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006102 ! IPYR_HUMAN [Term] id: CCO:I0019797 name: pqbp1-med31 physical interaction xref: IntAct:EBI-730576 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN [Term] id: CCO:I0019798 name: pqbp1-eef1a1 physical interaction xref: IntAct:EBI-730579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN [Term] id: CCO:I0019799 name: prkra-cops6 physical interaction xref: IntAct:EBI-730597 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0054651 ! PRKRA_HUMAN [Term] id: CCO:I0019800 name: prkra-gdf9 physical interaction xref: IntAct:EBI-730600 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0054651 ! PRKRA_HUMAN [Term] id: CCO:I0019801 name: prkra-prkra physical interaction xref: IntAct:EBI-730603 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054651 ! PRKRA_HUMAN [Term] id: CCO:I0019802 name: prkra-setdb1 physical interaction xref: IntAct:EBI-730606 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0054651 ! PRKRA_HUMAN [Term] id: CCO:I0019803 name: psmd11-setdb1 physical interaction xref: IntAct:EBI-730621 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0019804 name: psmd11-zhx1 physical interaction xref: IntAct:EBI-730624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006103 ! PSD11_HUMAN [Term] id: CCO:I0019805 name: ptpn4-htatip physical interaction xref: IntAct:EBI-730630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063349 ! PTN4_HUMAN [Term] id: CCO:I0019806 name: ptprs-htatip physical interaction xref: IntAct:EBI-730633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006104 ! PTPRS_HUMAN [Term] id: CCO:I0019807 name: pxmp3-tle1 physical interaction xref: IntAct:EBI-730648 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0063388 ! PEX2_HUMAN [Term] id: CCO:I0019808 name: rabif-utp14a physical interaction xref: IntAct:EBI-730654 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0055383 ! MSS4_HUMAN [Term] id: CCO:I0019809 name: rfc5-cops6 physical interaction xref: IntAct:EBI-730663 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0019810 name: rfc5-dkfzp564o0523 physical interaction xref: IntAct:EBI-730666 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019811 name: rfc5-eef1a1 physical interaction xref: IntAct:EBI-730669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN [Term] id: CCO:I0019812 name: rnf10-setdb1 physical interaction xref: IntAct:EBI-730681 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006230 ! RNF10_HUMAN [Term] id: CCO:I0019813 name: rnf10-tle1 physical interaction xref: IntAct:EBI-730684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006230 ! RNF10_HUMAN [Term] id: CCO:I0019814 name: rpa2-cops6 physical interaction xref: IntAct:EBI-730690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0019815 name: rpa2-dkfzp564o0523 physical interaction xref: IntAct:EBI-730693 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019816 name: rpl29-chd3 physical interaction xref: IntAct:EBI-730702 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0028895 ! RL29_HUMAN [Term] id: CCO:I0019817 name: rplp1-g22p1 physical interaction xref: IntAct:EBI-730705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005770 ! RLA1_HUMAN [Term] id: CCO:I0019818 name: rps10-pfn2 physical interaction xref: IntAct:EBI-730708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005749 ! RS10_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0019819 name: safb-chd3 physical interaction xref: IntAct:EBI-730735 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0056062 ! SAFB1_HUMAN [Term] id: CCO:I0019820 name: crlz1-zhx1 physical interaction xref: IntAct:EBI-730741 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006160 ! SAS10_HUMAN [Term] id: CCO:I0019821 name: sat-aplp1 physical interaction xref: IntAct:EBI-730744 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006107 ! SAT1_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019822 name: sat-med31 physical interaction xref: IntAct:EBI-730747 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019823 name: sat-ephb6 physical interaction xref: IntAct:EBI-730753 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006024 ! EPHB6_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019824 name: sat-myst2 physical interaction xref: IntAct:EBI-730759 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019825 name: sat-setdb1 physical interaction xref: IntAct:EBI-730768 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019826 name: sat-zhx1 physical interaction xref: IntAct:EBI-730774 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0019827 name: serpinb9-c14orf1 physical interaction xref: IntAct:EBI-730783 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019828 name: serpinb9-cops6 physical interaction xref: IntAct:EBI-730786 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0019829 name: serpinb9-fnbp3 physical interaction xref: IntAct:EBI-730789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0062999 ! PR40A_HUMAN [Term] id: CCO:I0019830 name: serpinb9-g22p1 physical interaction xref: IntAct:EBI-730792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0019831 name: serpinb9-igsf21 physical interaction xref: IntAct:EBI-730798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0019832 name: serpinb9-setdb1 physical interaction xref: IntAct:EBI-730801 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0019833 name: serpinb9-zhx1 physical interaction xref: IntAct:EBI-730804 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN [Term] id: CCO:I0019834 name: sh3gl1-sh3gl3 physical interaction xref: IntAct:EBI-730813 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN [Term] id: CCO:I0019835 name: sirt6-vim physical interaction xref: IntAct:EBI-730819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0057492 ! SIRT6_HUMAN [Term] id: CCO:I0019836 name: sma3-setdb1 physical interaction xref: IntAct:EBI-730828 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0041277 ! GUSP1_HUMAN [Term] id: CCO:I0019837 name: snap25-stx11 physical interaction xref: IntAct:EBI-730843 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005220 ! STX11_HUMAN relationship: has_participant CCO:B0055598 ! SNP25_HUMAN [Term] id: CCO:I0019838 name: snapap-htatip physical interaction xref: IntAct:EBI-730852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0043870 ! SNAPN_HUMAN [Term] id: CCO:I0019839 name: snapap-myst2 physical interaction xref: IntAct:EBI-730858 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0043870 ! SNAPN_HUMAN [Term] id: CCO:I0019840 name: snrpg-tle1 physical interaction xref: IntAct:EBI-730879 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005495 ! RUXG_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0019841 name: snrpn-sh3gl3 physical interaction xref: IntAct:EBI-730885 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006111 ! RSMN_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0019842 name: ssr1-eef1a1 physical interaction xref: IntAct:EBI-730900 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006163 ! SSRA_HUMAN [Term] id: CCO:I0019843 name: stmn2-eef1a1 physical interaction xref: IntAct:EBI-730906 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0023034 ! STMN2_HUMAN [Term] id: CCO:I0019844 name: sult1e1-setdb1 physical interaction xref: IntAct:EBI-730927 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006112 ! ST1E1_HUMAN [Term] id: CCO:I0019845 name: taf9-dkfzp564o0523 physical interaction xref: IntAct:EBI-730936 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019846 name: tardbp-setdb1 physical interaction xref: IntAct:EBI-730939 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063162 ! TADBP_HUMAN [Term] id: CCO:I0019847 name: tardbp-zhx1 physical interaction xref: IntAct:EBI-730942 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0063162 ! TADBP_HUMAN [Term] id: CCO:I0019848 name: tfg-crmp1 physical interaction xref: IntAct:EBI-730954 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:I0019849 name: tfg-kiaa1377 physical interaction xref: IntAct:EBI-730957 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:I0019850 name: tfg-tfg-2 physical interaction xref: IntAct:EBI-730960 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:I0019851 name: tgif-med31 physical interaction xref: IntAct:EBI-730963 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006246 ! TGIF1_HUMAN [Term] id: CCO:I0019852 name: tgif-eef1a1 physical interaction xref: IntAct:EBI-730966 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006246 ! TGIF1_HUMAN [Term] id: CCO:I0019853 name: th1l-mta1 physical interaction xref: IntAct:EBI-730969 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055899 ! MTA1_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0019854 name: timp1-recql5 physical interaction xref: IntAct:EBI-730972 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN relationship: has_participant CCO:B0054831 ! TIMP1_HUMAN [Term] id: CCO:I0019855 name: tk1-aplp1 physical interaction xref: IntAct:EBI-730975 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019856 name: tk1-c14orf1 physical interaction xref: IntAct:EBI-730978 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019857 name: tk1-cops6 physical interaction xref: IntAct:EBI-730981 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0019858 name: tk1-dkfzp564o0523 physical interaction xref: IntAct:EBI-730984 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019859 name: tk1-drap1 physical interaction xref: IntAct:EBI-730987 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN [Term] id: CCO:I0019860 name: tk1-setdb1 physical interaction xref: IntAct:EBI-730990 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006114 ! KITH_HUMAN [Term] id: CCO:I0019861 name: tm4sf1-ddr1 physical interaction xref: IntAct:EBI-730996 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006158 ! DDR1_HUMAN relationship: has_participant CCO:B0063389 ! T4S1_HUMAN [Term] id: CCO:I0019862 name: tmprss3-rxra physical interaction xref: IntAct:EBI-730999 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024886 ! RXRA_HUMAN relationship: has_participant CCO:B0063390 ! TMPS3_HUMAN [Term] id: CCO:I0019863 name: tmsb4x-eef1a1 physical interaction xref: IntAct:EBI-731002 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006115 ! TYB4_HUMAN [Term] id: CCO:I0019864 name: tmsb4x-tle1 physical interaction xref: IntAct:EBI-731008 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006115 ! TYB4_HUMAN [Term] id: CCO:I0019865 name: tnfrsf6-eef1a1 physical interaction xref: IntAct:EBI-731011 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN [Term] id: CCO:I0019866 name: tp53i3-eef1g physical interaction xref: IntAct:EBI-731047 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0056356 ! QORX_HUMAN [Term] id: CCO:I0019867 name: tp53i3-ubr1 physical interaction xref: IntAct:EBI-731050 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006135 ! UBR1_HUMAN relationship: has_participant CCO:B0056356 ! QORX_HUMAN [Term] id: CCO:I0019868 name: trim28-chd3 physical interaction xref: IntAct:EBI-731053 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0019869 name: ttr-chd3 physical interaction xref: IntAct:EBI-731056 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063374 ! TTHY_HUMAN [Term] id: CCO:I0019870 name: ttr-setdb1 physical interaction xref: IntAct:EBI-731059 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063374 ! TTHY_HUMAN [Term] id: CCO:I0019871 name: tubb4-tf physical interaction xref: IntAct:EBI-731074 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006167 ! TBB4_HUMAN relationship: has_participant CCO:B0054876 ! TRFE_HUMAN [Term] id: CCO:I0019872 name: ube2b-med31 physical interaction xref: IntAct:EBI-731077 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0063391 ! UBE2B_HUMAN [Term] id: CCO:I0019873 name: ulk2-luc7l2 physical interaction xref: IntAct:EBI-731089 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN relationship: has_participant CCO:B0006252 ! ULK2_HUMAN [Term] id: CCO:I0019874 name: ulk2-setdb1 physical interaction xref: IntAct:EBI-731092 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006252 ! ULK2_HUMAN [Term] id: CCO:I0019875 name: vim-myst2 physical interaction xref: IntAct:EBI-731101 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0019876 name: wdr33-git1 physical interaction xref: IntAct:EBI-731107 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:I0019877 name: wdr33-hrmt1l2 physical interaction xref: IntAct:EBI-731110 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:I0019878 name: ywhaz-g22p1 physical interaction xref: IntAct:EBI-731116 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN [Term] id: CCO:I0019879 name: zfp64-setdb1 physical interaction xref: IntAct:EBI-731119 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0037139 ! ZF64A_HUMAN [Term] id: CCO:I0019880 name: zfp64-unc119 physical interaction xref: IntAct:EBI-731122 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0037139 ! ZF64A_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019881 name: znf24-aplp1 physical interaction xref: IntAct:EBI-731125 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019882 name: znf24-c14orf1 physical interaction xref: IntAct:EBI-731128 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019883 name: znf24-cops6 physical interaction xref: IntAct:EBI-731131 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0006133 ! CSN6_HUMAN [Term] id: CCO:I0019884 name: znf24-hap1 physical interaction xref: IntAct:EBI-731134 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0006153 ! HAP1_HUMAN [Term] id: CCO:I0019885 name: znf24-utp14a physical interaction xref: IntAct:EBI-731137 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0006134 ! UT14A_HUMAN [Term] id: CCO:I0019886 name: znf24-setdb1 physical interaction xref: IntAct:EBI-731140 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN [Term] id: CCO:I0019887 name: znf499-med31 physical interaction xref: IntAct:EBI-731143 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0058252 ! ZBT45_HUMAN [Term] id: CCO:I0019888 name: abcd4-g22p1 physical interaction xref: IntAct:EBI-731161 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0006268 ! ABCD4_HUMAN [Term] id: CCO:I0019889 name: abcd4-pea15 physical interaction xref: IntAct:EBI-731164 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006268 ! ABCD4_HUMAN relationship: has_participant CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:I0019890 name: akr1c3-zhx1 physical interaction xref: IntAct:EBI-731173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006117 ! AK1C3_HUMAN [Term] id: CCO:I0019891 name: alb-luc7l2 physical interaction xref: IntAct:EBI-731176 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN relationship: has_participant CCO:B0054874 ! ALBU_HUMAN [Term] id: CCO:I0019892 name: anxa3-igsf21 physical interaction xref: IntAct:EBI-731185 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006119 ! ANXA3_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0019893 name: aof2-setdb1 physical interaction xref: IntAct:EBI-731188 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005589 ! LSD1_HUMAN [Term] id: CCO:I0019894 name: aplp1-utp14a physical interaction xref: IntAct:EBI-731194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0019895 name: arf1-wbp11 physical interaction xref: IntAct:EBI-731197 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005313 ! WBP11_HUMAN relationship: has_participant CCO:B0015288 ! ARF1_HUMAN [Term] id: CCO:I0019896 name: arf4l-eprs physical interaction xref: IntAct:EBI-731200 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN relationship: has_participant CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:I0019897 name: arhgdia-jup physical interaction xref: IntAct:EBI-731215 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005684 ! PLAK_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN [Term] id: CCO:I0019898 name: arih2-il4r physical interaction xref: IntAct:EBI-731230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005288 ! ARI2_HUMAN relationship: has_participant CCO:B0055171 ! IL4RA_HUMAN [Term] id: CCO:I0019899 name: arrb2-med8 physical interaction xref: IntAct:EBI-731248 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0055250 ! ARRB2_HUMAN [Term] id: CCO:I0019900 name: arrb2-stc2 physical interaction xref: IntAct:EBI-731251 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006237 ! STC2_HUMAN relationship: has_participant CCO:B0055250 ! ARRB2_HUMAN [Term] id: CCO:I0019901 name: asah1-setdb1 physical interaction xref: IntAct:EBI-731257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063392 ! ASAH1_HUMAN [Term] id: CCO:I0019902 name: ascc2-c9orf74 physical interaction xref: IntAct:EBI-731263 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0006312 ! URM1_HUMAN [Term] id: CCO:I0019903 name: ascc2-flj10324 physical interaction xref: IntAct:EBI-731266 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0043449 ! Q75LH2_HUMAN [Term] id: CCO:I0019904 name: ascc2-gtf3c1 physical interaction xref: IntAct:EBI-731269 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:I0019905 name: ascc2-fundc2 physical interaction xref: IntAct:EBI-731272 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0063393 ! FUND2_HUMAN [Term] id: CCO:I0019906 name: ascc2-immt physical interaction xref: IntAct:EBI-731275 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:I0019907 name: ascc2-myh9 physical interaction xref: IntAct:EBI-731278 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN [Term] id: CCO:I0019908 name: ascc2-pin4 physical interaction xref: IntAct:EBI-731281 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0063394 ! PIN4_HUMAN [Term] id: CCO:I0019909 name: ascc2-pja1 physical interaction xref: IntAct:EBI-731284 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0006202 ! PJA1_HUMAN [Term] id: CCO:I0019910 name: ascc2-poldip2 physical interaction xref: IntAct:EBI-731287 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0063380 ! PDIP2_HUMAN [Term] id: CCO:I0019911 name: ascc2-snrpb physical interaction xref: IntAct:EBI-731290 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0043440 ! RSMB_HUMAN [Term] id: CCO:I0019912 name: ascc2-tbc1d17 physical interaction xref: IntAct:EBI-731293 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:I0019913 name: ash2l-unc119 physical interaction xref: IntAct:EBI-731296 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0019914 name: atf3-igsf21 physical interaction xref: IntAct:EBI-731299 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006121 ! ATF3_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0019915 name: atp5c1-u222 physical interaction xref: IntAct:EBI-731314 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006122 ! ATPG_HUMAN relationship: has_participant CCO:B0055594 ! ELOF1_HUMAN [Term] id: CCO:I0019916 name: atp5c1-pcqap physical interaction xref: IntAct:EBI-731317 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0006122 ! ATPG_HUMAN [Term] id: CCO:I0019917 name: atp5j2-aof2 physical interaction xref: IntAct:EBI-731323 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005589 ! LSD1_HUMAN relationship: has_participant CCO:B0063395 ! ATPK_HUMAN [Term] id: CCO:I0019918 name: atp6ap1-ang physical interaction xref: IntAct:EBI-731338 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006220 ! ANGI_HUMAN relationship: has_participant CCO:B0063396 ! VAS1_HUMAN [Term] id: CCO:I0019919 name: atrx-kiaa1377 physical interaction xref: IntAct:EBI-731350 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0005879 ! ATRX_HUMAN [Term] id: CCO:I0019920 name: atrx-luc7l2 physical interaction xref: IntAct:EBI-731353 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005879 ! ATRX_HUMAN relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN [Term] id: CCO:I0019921 name: atrx-ptpn4 physical interaction xref: IntAct:EBI-731359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005879 ! ATRX_HUMAN relationship: has_participant CCO:B0063349 ! PTN4_HUMAN [Term] id: CCO:I0019922 name: q6zuh1-centa1 physical interaction xref: IntAct:EBI-731374 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043443 ! CENA1_HUMAN relationship: has_participant CCO:B0063397 ! Q6ZUH1_HUMAN [Term] id: CCO:I0019923 name: bcar1-fxyd6 physical interaction xref: IntAct:EBI-731383 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0006141 ! FXYD6_HUMAN [Term] id: CCO:I0019924 name: bcar1-tuba1 physical interaction xref: IntAct:EBI-731389 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005449 ! TBA4A_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN [Term] id: CCO:I0019925 name: bcar1-vps11 physical interaction xref: IntAct:EBI-731392 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0063398 ! VPS11_HUMAN [Term] id: CCO:I0019926 name: bcr-igsf21 physical interaction xref: IntAct:EBI-731395 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006123 ! BCR_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0019927 name: brix-setdb1 physical interaction xref: IntAct:EBI-731413 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063399 ! Q9NUW4_HUMAN [Term] id: CCO:I0019928 name: btbd2-gdf9 physical interaction xref: IntAct:EBI-731428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005933 ! BTBD2_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0019929 name: fra10ac1-eef1d physical interaction xref: IntAct:EBI-731440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021069 ! EF1D_HUMAN relationship: has_participant CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:I0019930 name: ylpm1-hrmt1l2 physical interaction xref: IntAct:EBI-731452 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0063400 ! YLPM1_HUMAN [Term] id: CCO:I0019931 name: c19orf14-tbp physical interaction xref: IntAct:EBI-731461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0006173 ! WDR62_HUMAN [Term] id: CCO:I0019932 name: c7orf19-gdf9 physical interaction xref: IntAct:EBI-731470 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0063401 ! ORA2P_HUMAN [Term] id: CCO:I0019933 name: c7orf19-setdb1 physical interaction xref: IntAct:EBI-731473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063401 ! ORA2P_HUMAN [Term] id: CCO:I0019934 name: c7orf20-capns1 physical interaction xref: IntAct:EBI-731479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0006174 ! CG020_HUMAN [Term] id: CCO:I0019935 name: c9orf46-g22p1 physical interaction xref: IntAct:EBI-731491 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0063402 ! CI046_HUMAN [Term] id: CCO:I0019936 name: c9orf82-myst2 physical interaction xref: IntAct:EBI-731494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0006175 ! CI082_HUMAN [Term] id: CCO:I0019937 name: cacnb4-med31 physical interaction xref: IntAct:EBI-731500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006176 ! CACB4_HUMAN [Term] id: CCO:I0019938 name: casp8-casp8 physical interaction xref: IntAct:EBI-731506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0019939 name: casp8-chd3 physical interaction xref: IntAct:EBI-731509 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0019940 name: cbx8-hap1 physical interaction xref: IntAct:EBI-731515 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:I0019941 name: cbx8-setdb1 physical interaction xref: IntAct:EBI-731518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0058797 ! CBX8_HUMAN [Term] id: CCO:I0019942 name: ccl18-c14orf1 physical interaction xref: IntAct:EBI-731521 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006087 ! CCL18_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019943 name: cdc42-htatip physical interaction xref: IntAct:EBI-731524 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN [Term] id: CCO:I0019944 name: cdk5rap2-mageh1 physical interaction xref: IntAct:EBI-731533 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005406 ! MAGH1_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN [Term] id: CCO:I0019945 name: cdk5rap2-senp2 physical interaction xref: IntAct:EBI-731539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN relationship: has_participant CCO:B0036139 ! SENP2_HUMAN [Term] id: CCO:I0019946 name: cdk5rap2-znf259 physical interaction xref: IntAct:EBI-731542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN relationship: has_participant CCO:B0018024 ! ZPR1_HUMAN [Term] id: CCO:I0019947 name: chn2-bat3 physical interaction xref: IntAct:EBI-731572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0055500 ! CHIO_HUMAN [Term] id: CCO:I0019948 name: chn2-sumo2 physical interaction xref: IntAct:EBI-731575 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055500 ! CHIO_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0019949 name: commd3-znf337 physical interaction xref: IntAct:EBI-731587 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059340 ! ZN337_HUMAN relationship: has_participant CCO:B0063403 ! COMD3_HUMAN [Term] id: CCO:I0019950 name: klf6-apom physical interaction xref: IntAct:EBI-731590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058431 ! KLF6_HUMAN relationship: has_participant CCO:B0063404 ! APOM_HUMAN [Term] id: CCO:I0019951 name: klf6-gtf3c1 physical interaction xref: IntAct:EBI-731593 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN relationship: has_participant CCO:B0058431 ! KLF6_HUMAN [Term] id: CCO:I0019952 name: klf6-loc56902 physical interaction xref: IntAct:EBI-731596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006240 ! PNO1_HUMAN relationship: has_participant CCO:B0058431 ! KLF6_HUMAN [Term] id: CCO:I0019953 name: klf6-pola2 physical interaction xref: IntAct:EBI-731599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0058431 ! KLF6_HUMAN [Term] id: CCO:I0019954 name: cpe-chd3 physical interaction xref: IntAct:EBI-731614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006081 ! CBPE_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0019955 name: cpe-gtf3c1 physical interaction xref: IntAct:EBI-731617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006081 ! CBPE_HUMAN relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:I0019956 name: cpe-pola2 physical interaction xref: IntAct:EBI-731620 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006081 ! CBPE_HUMAN [Term] id: CCO:I0019957 name: cradd-c14orf1 physical interaction xref: IntAct:EBI-731623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019958 name: cradd-eef1a1 physical interaction xref: IntAct:EBI-731626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006182 ! CRADD_HUMAN [Term] id: CCO:I0019959 name: creb1-c14orf1 physical interaction xref: IntAct:EBI-731635 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0019960 name: creld1-htatip physical interaction xref: IntAct:EBI-731638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006132 ! CREL1_HUMAN [Term] id: CCO:I0019961 name: creld1-pola2 physical interaction xref: IntAct:EBI-731641 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006132 ! CREL1_HUMAN [Term] id: CCO:I0019962 name: crip1-hap1 physical interaction xref: IntAct:EBI-731647 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0048870 ! CRIP1_HUMAN [Term] id: CCO:I0019963 name: crip1-sh3gl3 physical interaction xref: IntAct:EBI-731650 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0048870 ! CRIP1_HUMAN [Term] id: CCO:I0019964 name: ctsb-bat3 physical interaction xref: IntAct:EBI-731656 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0006345 ! CATB_HUMAN [Term] id: CCO:I0019965 name: dctn2-gnao1 physical interaction xref: IntAct:EBI-731659 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005177 ! DCTN2_HUMAN relationship: has_participant CCO:B0049381 ! GNAO_HUMAN [Term] id: CCO:I0019966 name: ddx24-eif4a2 physical interaction xref: IntAct:EBI-731668 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN relationship: has_participant CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:I0019967 name: ddx24-sptan1 physical interaction xref: IntAct:EBI-731677 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006183 ! DDX24_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0019968 name: c4orf17-chd3 physical interaction xref: IntAct:EBI-731680 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063405 ! CD017_HUMAN [Term] id: CCO:I0019969 name: c4orf17-sh3gl3 physical interaction xref: IntAct:EBI-731686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063405 ! CD017_HUMAN [Term] id: CCO:I0019970 name: dlst-pfn2 physical interaction xref: IntAct:EBI-731710 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0006185 ! ODO2_HUMAN [Term] id: CCO:I0019971 name: dnajb9-dncl1 physical interaction xref: IntAct:EBI-731716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006137 ! DNJB9_HUMAN relationship: has_participant CCO:B0006226 ! DYL1_HUMAN [Term] id: CCO:I0019972 name: dnajb9-fscn1 physical interaction xref: IntAct:EBI-731719 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006137 ! DNJB9_HUMAN relationship: has_participant CCO:B0056170 ! FSCN1_HUMAN [Term] id: CCO:I0019973 name: dnajb9-tcea2 physical interaction xref: IntAct:EBI-731725 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006137 ! DNJB9_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0019974 name: dnm1-med31 physical interaction xref: IntAct:EBI-731728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0022139 ! DYN1_HUMAN [Term] id: CCO:I0019975 name: dnmt2-cops6 physical interaction xref: IntAct:EBI-731731 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN [Term] id: CCO:I0019976 name: dnmt2-dkfzp564o0523 physical interaction xref: IntAct:EBI-731734 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0019977 name: dnmt2-utp14a physical interaction xref: IntAct:EBI-731737 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN [Term] id: CCO:I0019978 name: dnmt2-stx1a physical interaction xref: IntAct:EBI-731740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN relationship: has_participant CCO:B0056163 ! STX1A_HUMAN [Term] id: CCO:I0019979 name: dppa4-sh3gl1 physical interaction xref: IntAct:EBI-731743 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN relationship: has_participant CCO:B0062834 ! DPPA4_HUMAN [Term] id: CCO:I0019980 name: sh3gl1-dppa4 physical interaction xref: IntAct:EBI-731746 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN relationship: has_participant CCO:B0062834 ! DPPA4_HUMAN [Term] id: CCO:I0019981 name: dppa4-sh3gl3 physical interaction xref: IntAct:EBI-731749 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0062834 ! DPPA4_HUMAN [Term] id: CCO:I0019982 name: ebi2-mta1 physical interaction xref: IntAct:EBI-731761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055899 ! MTA1_HUMAN relationship: has_participant CCO:B0063406 ! GP183_HUMAN [Term] id: CCO:I0019983 name: efna1-htatip physical interaction xref: IntAct:EBI-731770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006269 ! EFNA1_HUMAN [Term] id: CCO:I0019984 name: eif3s5-ga17 physical interaction xref: IntAct:EBI-731791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026277 ! EIF3F_HUMAN relationship: has_participant CCO:B0063407 ! EIF3M_HUMAN [Term] id: CCO:I0019985 name: ell3-fth1 physical interaction xref: IntAct:EBI-731794 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033704 ! FRIH_HUMAN relationship: has_participant CCO:B0058778 ! ELL3_HUMAN [Term] id: CCO:I0019986 name: emd-sh3gl2 physical interaction xref: IntAct:EBI-731803 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:I0019987 name: emd-sh3gl3 physical interaction xref: IntAct:EBI-731806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0062869 ! EMD_HUMAN [Term] id: CCO:I0019988 name: ems1-chd3 physical interaction xref: IntAct:EBI-731809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063408 ! Q76MU0_HUMAN [Term] id: CCO:I0019989 name: eno2-map4 physical interaction xref: IntAct:EBI-731821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006270 ! ENOG_HUMAN relationship: has_participant CCO:B0055196 ! MAP4_HUMAN [Term] id: CCO:I0019990 name: epb49-dncli2 physical interaction xref: IntAct:EBI-731827 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055791 ! DEMA_HUMAN relationship: has_participant CCO:B0063409 ! DC1L2_HUMAN [Term] id: CCO:I0019991 name: eps8-mrpl20 physical interaction xref: IntAct:EBI-731833 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006248 ! RM20_HUMAN relationship: has_participant CCO:B0019772 ! EPS8_HUMAN [Term] id: CCO:I0019992 name: eps8-myo15a physical interaction xref: IntAct:EBI-731836 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0063410 ! MYO15_HUMAN [Term] id: CCO:I0019993 name: fabp4-vim physical interaction xref: IntAct:EBI-731860 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0034068 ! FABP4_HUMAN [Term] id: CCO:I0019994 name: fgfr3-atf3 physical interaction xref: IntAct:EBI-731863 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN [Term] id: CCO:I0019995 name: fgfr3-chgb physical interaction xref: IntAct:EBI-731869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:I0019996 name: fgfr3-ctsk physical interaction xref: IntAct:EBI-731872 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0031707 ! CATK_HUMAN [Term] id: CCO:I0019997 name: fgfr3-flj10324 physical interaction xref: IntAct:EBI-731875 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0043449 ! Q75LH2_HUMAN [Term] id: CCO:I0019998 name: fgfr3-gtf3c1 physical interaction xref: IntAct:EBI-731878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:I0019999 name: fgfr3-krt8 physical interaction xref: IntAct:EBI-731881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005900 ! K2C8_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0020000 name: fgfr3-pola2 physical interaction xref: IntAct:EBI-731884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN [Term] id: CCO:I0020001 name: fgfr3-sma3 physical interaction xref: IntAct:EBI-731887 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0041277 ! GUSP1_HUMAN [Term] id: CCO:I0020002 name: flii-dlst physical interaction xref: IntAct:EBI-731890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006185 ! ODO2_HUMAN relationship: has_participant CCO:B0055869 ! FLII_HUMAN [Term] id: CCO:I0020003 name: rp5_965l7_1-pola2 physical interaction xref: IntAct:EBI-731914 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0063412 ! PR38A_HUMAN [Term] id: CCO:I0020004 name: c8orf33-git1 physical interaction xref: IntAct:EBI-731935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0063413 ! CH033_HUMAN [Term] id: CCO:I0020005 name: ftl-fth1 physical interaction xref: IntAct:EBI-731980 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006192 ! FRIL_HUMAN relationship: has_participant CCO:B0033704 ! FRIH_HUMAN [Term] id: CCO:I0020006 name: fus-hrmt1l2 physical interaction xref: IntAct:EBI-731989 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0063414 ! FUS_HUMAN [Term] id: CCO:I0020007 name: fxyd6-gdf9 physical interaction xref: IntAct:EBI-732004 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006141 ! FXYD6_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020008 name: gcsh-ing5 physical interaction xref: IntAct:EBI-732016 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005284 ! ING5_HUMAN relationship: has_participant CCO:B0062899 ! GCSH_HUMAN [Term] id: CCO:I0020009 name: gemin7-htatip physical interaction xref: IntAct:EBI-732022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063415 ! GEMI7_HUMAN [Term] id: CCO:I0020010 name: gnai2-tuba1 physical interaction xref: IntAct:EBI-732034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005449 ! TBA4A_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN [Term] id: CCO:I0020011 name: gnb2-capns1 physical interaction xref: IntAct:EBI-732037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0055623 ! GBB2_HUMAN [Term] id: CCO:I0020012 name: golgb1-pfn2 physical interaction xref: IntAct:EBI-732043 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:I0020013 name: golph2-rpa2 physical interaction xref: IntAct:EBI-732046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0006331 ! GOLM1_HUMAN [Term] id: CCO:I0020014 name: gpr51-sh3gl3 physical interaction xref: IntAct:EBI-732049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0041922 ! GABR2_HUMAN [Term] id: CCO:I0020015 name: gsn-tom1l1 physical interaction xref: IntAct:EBI-732070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006203 ! TM1L1_HUMAN relationship: has_participant CCO:B0051611 ! GELS_HUMAN [Term] id: CCO:I0020016 name: gstm4-aplp1 physical interaction xref: IntAct:EBI-732073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006144 ! GSTM4_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0020017 name: gstm4-med31 physical interaction xref: IntAct:EBI-732076 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006144 ! GSTM4_HUMAN [Term] id: CCO:I0020018 name: gstp1-loc56902 physical interaction xref: IntAct:EBI-732085 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN relationship: has_participant CCO:B0006240 ! PNO1_HUMAN [Term] id: CCO:I0020019 name: gtf2f1-fez1 physical interaction xref: IntAct:EBI-732088 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005354 ! T2FA_HUMAN relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN [Term] id: CCO:I0020020 name: hba1-hbb physical interaction xref: IntAct:EBI-732103 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006221 ! HBA_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0020021 name: hbxip-utp14a physical interaction xref: IntAct:EBI-732109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:I0020022 name: hla_dqa1-aplp1 physical interaction xref: IntAct:EBI-732118 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006147 ! HA23_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0020023 name: hla_dqa1-sh3gl2 physical interaction xref: IntAct:EBI-732121 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006147 ! HA23_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN [Term] id: CCO:I0020024 name: znhit4-cd81 physical interaction xref: IntAct:EBI-732124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006262 ! CD81_HUMAN relationship: has_participant CCO:B0061990 ! IN80B_HUMAN [Term] id: CCO:I0020025 name: hmgb1-c14orf1 physical interaction xref: IntAct:EBI-732127 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0020026 name: hmgb1-crmp1 physical interaction xref: IntAct:EBI-732130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN [Term] id: CCO:I0020027 name: hmox2-setdb1 physical interaction xref: IntAct:EBI-732139 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006148 ! HMOX2_HUMAN [Term] id: CCO:I0020028 name: olfml3-setdb1 physical interaction xref: IntAct:EBI-732145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0031800 ! OLFL3_HUMAN [Term] id: CCO:I0020029 name: triobp-vim physical interaction xref: IntAct:EBI-732151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0058684 ! TARA_HUMAN [Term] id: CCO:I0020030 name: hrmt1l2-igsf21 physical interaction xref: IntAct:EBI-732154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0020031 name: hspb1-igsf21 physical interaction xref: IntAct:EBI-732160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0020032 name: hspb1-pp physical interaction xref: IntAct:EBI-732163 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0006102 ! IPYR_HUMAN [Term] id: CCO:I0020033 name: hspb3-setdb1 physical interaction xref: IntAct:EBI-732178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006197 ! HSPB3_HUMAN [Term] id: CCO:I0020034 name: dkfzp434n1418-git1 physical interaction xref: IntAct:EBI-732190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0063416 ! CC113_HUMAN [Term] id: CCO:I0020035 name: dkfzp434n1418-pfn2 physical interaction xref: IntAct:EBI-732199 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0063416 ! CC113_HUMAN [Term] id: CCO:I0020036 name: hspca-hspca physical interaction xref: IntAct:EBI-732202 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005698 ! HS90A_HUMAN [Term] id: CCO:I0020037 name: hspe1-gbp2 physical interaction xref: IntAct:EBI-732205 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006092 ! CH10_HUMAN relationship: has_participant CCO:B0031499 ! GBP2_HUMAN [Term] id: CCO:I0020038 name: idh1-zhx1 physical interaction xref: IntAct:EBI-732226 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0050696 ! IDHC_HUMAN [Term] id: CCO:I0020039 name: igfbp3-gtf3c1 physical interaction xref: IntAct:EBI-732229 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN [Term] id: CCO:I0020040 name: ik-pfn2 physical interaction xref: IntAct:EBI-732232 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0006239 ! RED_HUMAN [Term] id: CCO:I0020041 name: itgb3bp-centb5 physical interaction xref: IntAct:EBI-732238 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0058318 ! CENB5_HUMAN [Term] id: CCO:I0020042 name: itgb3bp-creld1 physical interaction xref: IntAct:EBI-732241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006132 ! CREL1_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:I0020043 name: itgb3bp-fundc2 physical interaction xref: IntAct:EBI-732244 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063393 ! FUND2_HUMAN [Term] id: CCO:I0020044 name: itgb3bp-pdha1 physical interaction xref: IntAct:EBI-732247 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0025860 ! ODPA_HUMAN [Term] id: CCO:I0020045 name: itgb3bp-rpl6 physical interaction xref: IntAct:EBI-732253 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0055717 ! RL6_HUMAN [Term] id: CCO:I0020046 name: itgb3bp-upf3b physical interaction xref: IntAct:EBI-732256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005434 ! REN3B_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:I0020047 name: itsn1-mrpl20 physical interaction xref: IntAct:EBI-732259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006248 ! RM20_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0020048 name: itsn1-snx5 physical interaction xref: IntAct:EBI-732262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026585 ! SNX5_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0020049 name: itsn2-tbl3 physical interaction xref: IntAct:EBI-732282 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006199 ! ITSN2_HUMAN relationship: has_participant CCO:B0006309 ! TBL3_HUMAN [Term] id: CCO:I0020050 name: kctd15-ren physical interaction xref: IntAct:EBI-732291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054828 ! RENI_HUMAN relationship: has_participant CCO:B0063417 ! KCD15_HUMAN [Term] id: CCO:I0020051 name: kiaa0182-g22p1 physical interaction xref: IntAct:EBI-732297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005595 ! GSE1_HUMAN [Term] id: CCO:I0020052 name: lama4-sumo2 physical interaction xref: IntAct:EBI-732327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0020053 name: loc51236-pola2 physical interaction xref: IntAct:EBI-732354 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006094 ! Q96BK8_HUMAN [Term] id: CCO:I0020054 name: lrpap1-pola2 physical interaction xref: IntAct:EBI-732392 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006334 ! AMRP_HUMAN [Term] id: CCO:I0020055 name: lrpap1-rtn4 physical interaction xref: IntAct:EBI-732395 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006334 ! AMRP_HUMAN relationship: has_participant CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:I0020056 name: lypla2-med31 physical interaction xref: IntAct:EBI-732404 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006282 ! LYPA2_HUMAN [Term] id: CCO:I0020057 name: mafg-med31 physical interaction xref: IntAct:EBI-732416 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0042178 ! MAFG_HUMAN [Term] id: CCO:I0020058 name: mafg-dkfzp564o0523 physical interaction xref: IntAct:EBI-732419 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0042178 ! MAFG_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0020059 name: mafg-vim physical interaction xref: IntAct:EBI-732422 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0042178 ! MAFG_HUMAN [Term] id: CCO:I0020060 name: maged1-eif3s1 physical interaction xref: IntAct:EBI-732425 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0020061 name: maged1-gpr135 physical interaction xref: IntAct:EBI-732428 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0006306 ! GP135_HUMAN [Term] id: CCO:I0020062 name: maged1-rfx1 physical interaction xref: IntAct:EBI-732434 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0006243 ! RFX1_HUMAN [Term] id: CCO:I0020063 name: maged1-sirt7 physical interaction xref: IntAct:EBI-732437 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0058895 ! SIRT7_HUMAN [Term] id: CCO:I0020064 name: maged1-tuba1 physical interaction xref: IntAct:EBI-732440 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005449 ! TBA4A_HUMAN relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN [Term] id: CCO:I0020065 name: man2a2-git1 physical interaction xref: IntAct:EBI-732443 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0063384 ! MA2A2_HUMAN [Term] id: CCO:I0020066 name: man2a2-ikbkap physical interaction xref: IntAct:EBI-732446 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0063384 ! MA2A2_HUMAN [Term] id: CCO:I0020067 name: mapk9-acp5 physical interaction xref: IntAct:EBI-732461 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026769 ! MK09_HUMAN relationship: has_participant CCO:B0063418 ! PPA5_HUMAN [Term] id: CCO:I0020068 name: c16orf24-pfn2 physical interaction xref: IntAct:EBI-732485 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0061994 ! F173A_HUMAN [Term] id: CCO:I0020069 name: c16orf24-sh3gl3 physical interaction xref: IntAct:EBI-732488 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0061994 ! F173A_HUMAN [Term] id: CCO:I0020070 name: mgc3731-sap18 physical interaction xref: IntAct:EBI-732494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006113 ! SAP18_HUMAN relationship: has_participant CCO:B0006336 ! NOL12_HUMAN [Term] id: CCO:I0020071 name: mgc5352-hspa1a physical interaction xref: IntAct:EBI-732515 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0063419 ! PGAM5_HUMAN [Term] id: CCO:I0020072 name: mgc5352-setdb1 physical interaction xref: IntAct:EBI-732518 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063419 ! PGAM5_HUMAN [Term] id: CCO:I0020073 name: mllt3-dkfzp564o0523 physical interaction xref: IntAct:EBI-732521 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006206 ! AF9_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0020074 name: mllt3-eef1a1 physical interaction xref: IntAct:EBI-732524 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006206 ! AF9_HUMAN [Term] id: CCO:I0020075 name: mpp3-hap1 physical interaction xref: IntAct:EBI-732554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0006207 ! MPP3_HUMAN [Term] id: CCO:I0020076 name: mrpl42-ikbkap physical interaction xref: IntAct:EBI-732560 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0063420 ! Q6FID1_HUMAN [Term] id: CCO:I0020077 name: mycbp-cops6 physical interaction xref: IntAct:EBI-732572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN [Term] id: CCO:I0020078 name: mycbp-gdf9 physical interaction xref: IntAct:EBI-732575 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN [Term] id: CCO:I0020079 name: myh9-myl9 physical interaction xref: IntAct:EBI-732581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0063421 ! MYL9_HUMAN [Term] id: CCO:I0020080 name: naca-aplp1 physical interaction xref: IntAct:EBI-732584 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006096 ! NACA_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0020081 name: nap1l1-dlst physical interaction xref: IntAct:EBI-732590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0006185 ! ODO2_HUMAN [Term] id: CCO:I0020082 name: ndufa6-tbpl1 physical interaction xref: IntAct:EBI-732614 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055618 ! TBPL1_HUMAN relationship: has_participant CCO:B0063422 ! NDUA6_HUMAN [Term] id: CCO:I0020083 name: ndufb8-pfn2 physical interaction xref: IntAct:EBI-732617 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0006289 ! NDUB8_HUMAN [Term] id: CCO:I0020084 name: ndufb9-ikbkap physical interaction xref: IntAct:EBI-732623 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0063423 ! NDUB9_HUMAN [Term] id: CCO:I0020085 name: ndufb9-sh3gl3 physical interaction xref: IntAct:EBI-732626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063423 ! NDUB9_HUMAN [Term] id: CCO:I0020086 name: ndufv2-htatip physical interaction xref: IntAct:EBI-732629 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063424 ! NDUV2_HUMAN [Term] id: CCO:I0020087 name: nfatc2-med31 physical interaction xref: IntAct:EBI-732635 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:I0020088 name: nfatc2-vim physical interaction xref: IntAct:EBI-732638 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN [Term] id: CCO:I0020089 name: nif3l1bp1-chd3 physical interaction xref: IntAct:EBI-732668 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063425 ! THOC7_HUMAN [Term] id: CCO:I0020090 name: nipsnap3a-ikbkap physical interaction xref: IntAct:EBI-732674 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0063426 ! NPS3A_HUMAN [Term] id: CCO:I0020091 name: nipsnap3a-setdb1 physical interaction xref: IntAct:EBI-732680 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063426 ! NPS3A_HUMAN [Term] id: CCO:I0020092 name: nit1-g22p1 physical interaction xref: IntAct:EBI-732683 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0063427 ! NIT1_HUMAN [Term] id: CCO:I0020093 name: np-dkfzp564o0523 physical interaction xref: IntAct:EBI-732686 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006097 ! PNPH_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0020094 name: pafah1b3-gdf9 physical interaction xref: IntAct:EBI-732728 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006098 ! PA1B3_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020095 name: pbp-stc2 physical interaction xref: IntAct:EBI-732743 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006237 ! STC2_HUMAN relationship: has_participant CCO:B0027514 ! PEBP1_HUMAN [Term] id: CCO:I0020096 name: pcdha4-gdf9 physical interaction xref: IntAct:EBI-732752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006099 ! PCDA4_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020097 name: pdcd5-acp5 physical interaction xref: IntAct:EBI-732761 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006152 ! PDCD5_HUMAN relationship: has_participant CCO:B0063418 ! PPA5_HUMAN [Term] id: CCO:I0020098 name: pdcd7-fez1 physical interaction xref: IntAct:EBI-732764 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0057517 ! PDCD7_HUMAN [Term] id: CCO:I0020099 name: pdcd7-hap1 physical interaction xref: IntAct:EBI-732767 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0057517 ! PDCD7_HUMAN [Term] id: CCO:I0020100 name: pdcd8-setdb1 physical interaction xref: IntAct:EBI-732770 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0020101 name: pdcd8-stc2 physical interaction xref: IntAct:EBI-732773 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006237 ! STC2_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0020102 name: pecam1-g22p1 physical interaction xref: IntAct:EBI-732776 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0026626 ! PECA1_HUMAN [Term] id: CCO:I0020103 name: pex14-smarcc2 physical interaction xref: IntAct:EBI-732791 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0054627 ! PEX14_HUMAN [Term] id: CCO:I0020104 name: pfkl-cops6 physical interaction xref: IntAct:EBI-732806 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0034104 ! K6PL_HUMAN [Term] id: CCO:I0020105 name: pfn1-c14orf1 physical interaction xref: IntAct:EBI-732809 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006154 ! PROF1_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0020106 name: pfn1-tle1 physical interaction xref: IntAct:EBI-732815 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006154 ! PROF1_HUMAN [Term] id: CCO:I0020107 name: phf10-utp14a physical interaction xref: IntAct:EBI-732821 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:I0020108 name: phf10-setdb1 physical interaction xref: IntAct:EBI-732824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:I0020109 name: phf10-unc119 physical interaction xref: IntAct:EBI-732827 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043869 ! U119A_HUMAN relationship: has_participant CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:I0020110 name: phyhip-med8 physical interaction xref: IntAct:EBI-732839 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0006241 ! PHYIP_HUMAN [Term] id: CCO:I0020111 name: plaur-eef1a1 physical interaction xref: IntAct:EBI-732851 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0055723 ! UPAR_HUMAN [Term] id: CCO:I0020112 name: plaur-sumo2 physical interaction xref: IntAct:EBI-732854 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055723 ! UPAR_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0020113 name: plaur-pfn2 physical interaction xref: IntAct:EBI-732857 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0055723 ! UPAR_HUMAN [Term] id: CCO:I0020114 name: plekha4-htatip physical interaction xref: IntAct:EBI-732863 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0006216 ! PKHA4_HUMAN [Term] id: CCO:I0020115 name: plekha4-setdb1 physical interaction xref: IntAct:EBI-732869 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006216 ! PKHA4_HUMAN [Term] id: CCO:I0020116 name: pola2-setdb1 physical interaction xref: IntAct:EBI-732890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN [Term] id: CCO:I0020117 name: polb-tle1 physical interaction xref: IntAct:EBI-732893 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0054905 ! DPOLB_HUMAN [Term] id: CCO:I0020118 name: ppid-myst2 physical interaction xref: IntAct:EBI-732908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0022232 ! PPID_HUMAN [Term] id: CCO:I0020119 name: ppp1r16a-txnrd1 physical interaction xref: IntAct:EBI-732920 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0039979 ! PP16A_HUMAN relationship: has_participant CCO:B0056179 ! TRXR1_HUMAN [Term] id: CCO:I0020120 name: ppp1r8-c14orf1 physical interaction xref: IntAct:EBI-732923 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006287 ! ERG28_HUMAN relationship: has_participant CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:I0020121 name: ppp1r8-dkfzp564o0523 physical interaction xref: IntAct:EBI-732926 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055860 ! PP1R8_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0020122 name: ppp1r8-gbp2 physical interaction xref: IntAct:EBI-732929 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031499 ! GBP2_HUMAN relationship: has_participant CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:I0020123 name: ppp1r8-stc2 physical interaction xref: IntAct:EBI-732932 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006237 ! STC2_HUMAN relationship: has_participant CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:I0020124 name: prei3-med31 physical interaction xref: IntAct:EBI-732941 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0020125 name: prei3-gdf9 physical interaction xref: IntAct:EBI-732944 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0020126 name: prei3-scmh1 physical interaction xref: IntAct:EBI-732953 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:I0020127 name: prei3-setdb1 physical interaction xref: IntAct:EBI-732956 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0020128 name: prg2-chd3 physical interaction xref: IntAct:EBI-732962 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063428 ! PRG2_HUMAN [Term] id: CCO:I0020129 name: psmd11-gdf9 physical interaction xref: IntAct:EBI-732974 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006103 ! PSD11_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020130 name: pth-bat3 physical interaction xref: IntAct:EBI-733019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0054847 ! PTHY_HUMAN [Term] id: CCO:I0020131 name: pth-fez1 physical interaction xref: IntAct:EBI-733022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0054847 ! PTHY_HUMAN [Term] id: CCO:I0020132 name: ptprs-chd3 physical interaction xref: IntAct:EBI-733028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006104 ! PTPRS_HUMAN [Term] id: CCO:I0020133 name: ptprs-pfn2 physical interaction xref: IntAct:EBI-733034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006104 ! PTPRS_HUMAN relationship: has_participant CCO:B0006155 ! PROF2_HUMAN [Term] id: CCO:I0020134 name: ptprs-setdb1 physical interaction xref: IntAct:EBI-733040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006104 ! PTPRS_HUMAN [Term] id: CCO:I0020135 name: qtrt1-setdb1 physical interaction xref: IntAct:EBI-733046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063429 ! TGT_HUMAN [Term] id: CCO:I0020136 name: qtrt1-sh3gl3 physical interaction xref: IntAct:EBI-733049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063429 ! TGT_HUMAN [Term] id: CCO:I0020137 name: rab1a-rfk physical interaction xref: IntAct:EBI-733061 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0063430 ! RIFK_HUMAN [Term] id: CCO:I0020138 name: rab27a-c14orf1 physical interaction xref: IntAct:EBI-733064 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006223 ! RB27A_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0020139 name: rab27a-cops6 physical interaction xref: IntAct:EBI-733067 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0006223 ! RB27A_HUMAN [Term] id: CCO:I0020140 name: rab27a-dkfzp564o0523 physical interaction xref: IntAct:EBI-733070 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006223 ! RB27A_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0020141 name: rab27a-gdf9 physical interaction xref: IntAct:EBI-733073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0006223 ! RB27A_HUMAN [Term] id: CCO:I0020142 name: rab27a-kiaa1377 physical interaction xref: IntAct:EBI-733076 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005403 ! K1377_HUMAN relationship: has_participant CCO:B0006223 ! RB27A_HUMAN [Term] id: CCO:I0020143 name: rgl2-htatip physical interaction xref: IntAct:EBI-733082 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063431 ! Q5STK0_HUMAN [Term] id: CCO:I0020144 name: rgl2-myst2 physical interaction xref: IntAct:EBI-733085 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0063431 ! Q5STK0_HUMAN [Term] id: CCO:I0020145 name: recql5-creb1 physical interaction xref: IntAct:EBI-733097 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN [Term] id: CCO:I0020146 name: reg1b-bat3 physical interaction xref: IntAct:EBI-733103 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0055401 ! REG1B_HUMAN [Term] id: CCO:I0020147 name: rer1-sh3gl3 physical interaction xref: IntAct:EBI-733109 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063432 ! RER1_HUMAN [Term] id: CCO:I0020148 name: rfc5-med31 physical interaction xref: IntAct:EBI-733112 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN [Term] id: CCO:I0020149 name: rgs1-fundc2 physical interaction xref: IntAct:EBI-733115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020780 ! RGS1_HUMAN relationship: has_participant CCO:B0063393 ! FUND2_HUMAN [Term] id: CCO:I0020150 name: rnpc4-pola2 physical interaction xref: IntAct:EBI-733151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006106 ! Q6IA98_HUMAN [Term] id: CCO:I0020151 name: rpl22-cse1l physical interaction xref: IntAct:EBI-733160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0005751 ! RL22_HUMAN [Term] id: CCO:I0020152 name: rpl35a-sh3gl3 physical interaction xref: IntAct:EBI-733163 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063048 ! RL35A_HUMAN [Term] id: CCO:I0020153 name: rps10-myst2 physical interaction xref: IntAct:EBI-733175 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005749 ! RS10_HUMAN [Term] id: CCO:I0020154 name: rps3a-c20orf31 physical interaction xref: IntAct:EBI-733178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0063433 ! EDEM2_HUMAN [Term] id: CCO:I0020155 name: rps3a-sap18 physical interaction xref: IntAct:EBI-733181 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0006113 ! SAP18_HUMAN [Term] id: CCO:I0020156 name: rps3a-sod2 physical interaction xref: IntAct:EBI-733184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0033778 ! SODM_HUMAN [Term] id: CCO:I0020157 name: rras2-g22p1 physical interaction xref: IntAct:EBI-733187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN [Term] id: CCO:I0020158 name: s100a10-setdb1 physical interaction xref: IntAct:EBI-733205 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0055600 ! S10AA_HUMAN [Term] id: CCO:I0020159 name: s100a4-bat3 physical interaction xref: IntAct:EBI-733208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0019310 ! S10A4_HUMAN [Term] id: CCO:I0020160 name: s100a4-unc119 physical interaction xref: IntAct:EBI-733211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019310 ! S10A4_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0020161 name: s100a8-gdf9 physical interaction xref: IntAct:EBI-733217 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006159 ! S10A8_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020162 name: sat-chd3 physical interaction xref: IntAct:EBI-733238 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006107 ! SAT1_HUMAN [Term] id: CCO:I0020163 name: sat-dgkz physical interaction xref: IntAct:EBI-733241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006107 ! SAT1_HUMAN relationship: has_participant CCO:B0055932 ! DGKZ_HUMAN [Term] id: CCO:I0020164 name: sat-gdf9 physical interaction xref: IntAct:EBI-733250 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006107 ! SAT1_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020165 name: serpinb9-ech1 physical interaction xref: IntAct:EBI-733292 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0063377 ! ECH1_HUMAN [Term] id: CCO:I0020166 name: serpinb9-gbp2 physical interaction xref: IntAct:EBI-733295 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0031499 ! GBP2_HUMAN [Term] id: CCO:I0020167 name: serpinb9-gdf9 physical interaction xref: IntAct:EBI-733298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020168 name: sfpq-sfpq physical interaction xref: IntAct:EBI-733307 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN [Term] id: CCO:I0020169 name: shmt1-pim1 physical interaction xref: IntAct:EBI-733310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006184 ! GLYC_HUMAN relationship: has_participant CCO:B0022781 ! PIM1_HUMAN [Term] id: CCO:I0020170 name: smn1-gdf9 physical interaction xref: IntAct:EBI-733334 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006110 ! SMN_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020171 name: snrpd2-htatip physical interaction xref: IntAct:EBI-733355 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0018244 ! SMD2_HUMAN [Term] id: CCO:I0020172 name: snrpg-gdf9 physical interaction xref: IntAct:EBI-733358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005495 ! RUXG_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020173 name: snta1-g22p1 physical interaction xref: IntAct:EBI-733361 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0063265 ! SNTA1_HUMAN [Term] id: CCO:I0020174 name: sqstm1-sqstm1 physical interaction xref: IntAct:EBI-733385 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN [Term] id: CCO:I0020175 name: ssr1-utp14a physical interaction xref: IntAct:EBI-733391 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0006163 ! SSRA_HUMAN [Term] id: CCO:I0020176 name: strn4-klhdc2 physical interaction xref: IntAct:EBI-733400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063434 ! KLDC2_HUMAN [Term] id: CCO:I0020177 name: stx1a-vim physical interaction xref: IntAct:EBI-733406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005737 ! VIME_HUMAN relationship: has_participant CCO:B0056163 ! STX1A_HUMAN [Term] id: CCO:I0020178 name: stx5a-aplp1 physical interaction xref: IntAct:EBI-733409 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006164 ! STX5_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0020179 name: syn1-htatip physical interaction xref: IntAct:EBI-733451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063435 ! SYN1_HUMAN [Term] id: CCO:I0020180 name: tac1-bat3 physical interaction xref: IntAct:EBI-733463 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0055119 ! TKN1_HUMAN [Term] id: CCO:I0020181 name: tac3-fez1 physical interaction xref: IntAct:EBI-733473 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0006242 ! TKNK_HUMAN [Term] id: CCO:I0020182 name: tac3-ikbkap physical interaction xref: IntAct:EBI-733479 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0006242 ! TKNK_HUMAN [Term] id: CCO:I0020183 name: tac3-ubr1 physical interaction xref: IntAct:EBI-733485 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006135 ! UBR1_HUMAN relationship: has_participant CCO:B0006242 ! TKNK_HUMAN [Term] id: CCO:I0020184 name: tbc1d17-gtf3c1 physical interaction xref: IntAct:EBI-733494 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN [Term] id: CCO:I0020185 name: tcea2-mark3 physical interaction xref: IntAct:EBI-733500 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005229 ! MARK3_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0020186 name: tdgf1-ang physical interaction xref: IntAct:EBI-733506 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006220 ! ANGI_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN [Term] id: CCO:I0020187 name: tdgf1-cops6 physical interaction xref: IntAct:EBI-733511 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN [Term] id: CCO:I0020188 name: tdgf1-gdf9 physical interaction xref: IntAct:EBI-733514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN [Term] id: CCO:I0020189 name: tfcp2-casp8 physical interaction xref: IntAct:EBI-733526 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055842 ! TFCP2_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN [Term] id: CCO:I0020190 name: tfg-c14orf1 physical interaction xref: IntAct:EBI-733529 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006287 ! ERG28_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:I0020191 name: tfg-gbp2 physical interaction xref: IntAct:EBI-733535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031499 ! GBP2_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN [Term] id: CCO:I0020192 name: th1l-dnaja1 physical interaction xref: IntAct:EBI-733541 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0020193 name: th1l-gstm4 physical interaction xref: IntAct:EBI-733544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006144 ! GSTM4_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0020194 name: th1l-hdac11 physical interaction xref: IntAct:EBI-733547 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005701 ! HDA11_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0020195 name: thap8-setdb1 physical interaction xref: IntAct:EBI-733550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006304 ! THAP8_HUMAN [Term] id: CCO:I0020196 name: tk1-gdf9 physical interaction xref: IntAct:EBI-733553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN [Term] id: CCO:I0020197 name: tk1-ptprk physical interaction xref: IntAct:EBI-733559 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0022999 ! PTPRK_HUMAN [Term] id: CCO:I0020198 name: tmsb4x-aplp1 physical interaction xref: IntAct:EBI-733568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006115 ! TYB4_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN [Term] id: CCO:I0020199 name: tmsb4x-igsf21 physical interaction xref: IntAct:EBI-733571 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006115 ! TYB4_HUMAN relationship: has_participant CCO:B0006168 ! IGS21_HUMAN [Term] id: CCO:I0020200 name: tnfrsf10c-zhx1 physical interaction xref: IntAct:EBI-733574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0063436 ! TR10C_HUMAN [Term] id: CCO:I0020201 name: tnfrsf14-chd3 physical interaction xref: IntAct:EBI-733577 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0020202 name: tnfrsf14-vim physical interaction xref: IntAct:EBI-733580 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0020203 name: tnfsf10-dkfzp564o052 physical interaction xref: IntAct:EBI-733586 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0020204 name: tollip-setdb1 physical interaction xref: IntAct:EBI-733598 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN [Term] id: CCO:I0020205 name: tollip-zhx1 physical interaction xref: IntAct:EBI-733601 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN [Term] id: CCO:I0020206 name: tpi1-setdb1 physical interaction xref: IntAct:EBI-733619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0015866 ! TPIS_HUMAN [Term] id: CCO:I0020207 name: trbv21_1-setdb1 physical interaction xref: IntAct:EBI-733628 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0006251 ! Q8N3Z8_HUMAN [Term] id: CCO:I0020208 name: trim28-spg7 physical interaction xref: IntAct:EBI-733631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0006236 ! SPG7_HUMAN [Term] id: CCO:I0020209 name: trim28-vim physical interaction xref: IntAct:EBI-733634 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0005737 ! VIME_HUMAN [Term] id: CCO:I0020210 name: tubb4-arhgef7 physical interaction xref: IntAct:EBI-733669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006167 ! TBB4_HUMAN relationship: has_participant CCO:B0055966 ! ARHG7_HUMAN [Term] id: CCO:I0020211 name: u5_116kd-arpc3 physical interaction xref: IntAct:EBI-733678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN relationship: has_participant CCO:B0063437 ! Q6IBM8_HUMAN [Term] id: CCO:I0020212 name: wdr33-myst2 physical interaction xref: IntAct:EBI-733704 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:I0020213 name: wdr33-pfn2 physical interaction xref: IntAct:EBI-733707 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:I0020214 name: wdr33-sh3gl3 physical interaction xref: IntAct:EBI-733713 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006169 ! WDR33_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0020215 name: wdr33-zhx1 physical interaction xref: IntAct:EBI-733716 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0006169 ! WDR33_HUMAN [Term] id: CCO:I0020216 name: xrcc4-chd3 physical interaction xref: IntAct:EBI-733722 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005651 ! XRCC4_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN [Term] id: CCO:I0020217 name: zfhx1b-cops6 physical interaction xref: IntAct:EBI-733740 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0054546 ! ZEB2_HUMAN [Term] id: CCO:I0020218 name: znf20-hap1 physical interaction xref: IntAct:EBI-733743 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0055069 ! ZNF20_HUMAN [Term] id: CCO:I0020219 name: acd-g22p1 physical interaction xref: IntAct:EBI-733752 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005504 ! ACD_HUMAN [Term] id: CCO:I0020220 name: acp6-gng7 physical interaction xref: IntAct:EBI-733789 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0024704 ! PPA6_HUMAN relationship: has_participant CCO:B0054537 ! GBG7_HUMAN [Term] id: CCO:I0020221 name: adam11-stc2 physical interaction xref: IntAct:EBI-733792 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006237 ! STC2_HUMAN relationship: has_participant CCO:B0038563 ! ADA11_HUMAN [Term] id: CCO:I0020222 name: adh5-chd3 physical interaction xref: IntAct:EBI-733795 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0038020 ! ADHX_HUMAN [Term] id: CCO:I0020223 name: aes-med31 physical interaction xref: IntAct:EBI-733798 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005987 ! AES_HUMAN [Term] id: CCO:I0020224 name: aes-sh3gl3 physical interaction xref: IntAct:EBI-733801 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005987 ! AES_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0020225 name: anxa5-fdft1 physical interaction xref: IntAct:EBI-733819 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015822 ! ANXA5_HUMAN relationship: has_participant CCO:B0027270 ! FDFT_HUMAN [Term] id: CCO:I0020226 name: aof2-immt physical interaction xref: IntAct:EBI-733825 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005589 ! LSD1_HUMAN relationship: has_participant CCO:B0006201 ! IMMT_HUMAN [Term] id: CCO:I0020227 name: aof2-unc119 physical interaction xref: IntAct:EBI-733831 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005589 ! LSD1_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0020228 name: arf1-c4orf14 physical interaction xref: IntAct:EBI-733837 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015288 ! ARF1_HUMAN relationship: has_participant CCO:B0026813 ! CD014_HUMAN [Term] id: CCO:I0020229 name: arf4l-dnaja1 physical interaction xref: IntAct:EBI-733840 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005835 ! DNJA1_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN [Term] id: CCO:I0020230 name: arf4l-mapk8ip3 physical interaction xref: IntAct:EBI-733846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006034 ! JIP3_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN [Term] id: CCO:I0020231 name: arf4l-ndrg1 physical interaction xref: IntAct:EBI-733849 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN relationship: has_participant CCO:B0063438 ! NDRG1_HUMAN [Term] id: CCO:I0020232 name: arf4l-pgam1 physical interaction xref: IntAct:EBI-733852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN relationship: has_participant CCO:B0006323 ! PGAM1_HUMAN [Term] id: CCO:I0020233 name: arf4l-prkcsh physical interaction xref: IntAct:EBI-733855 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006228 ! GLU2B_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN [Term] id: CCO:I0020234 name: arhgdia-baf53a physical interaction xref: IntAct:EBI-733861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016783 ! Q6FI97_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN [Term] id: CCO:I0020235 name: arhgdia-nedd4l physical interaction xref: IntAct:EBI-733867 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN relationship: has_participant CCO:B0034087 ! NED4L_HUMAN [Term] id: CCO:I0020236 name: arhgdia-sh3gl3 physical interaction xref: IntAct:EBI-733870 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063439 ! Q6IBM5_HUMAN [Term] id: CCO:I0020237 name: arpc3-hrmt1l2 physical interaction xref: IntAct:EBI-733898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN [Term] id: CCO:I0020238 name: arr3-capns1 physical interaction xref: IntAct:EBI-733901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0055311 ! ARRC_HUMAN [Term] id: CCO:I0020239 name: arr3-rnase6 physical interaction xref: IntAct:EBI-733904 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055311 ! ARRC_HUMAN relationship: has_participant CCO:B0063440 ! RNAS6_HUMAN [Term] id: CCO:I0020240 name: arrb2-smarcc2 physical interaction xref: IntAct:EBI-733907 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0055250 ! ARRB2_HUMAN [Term] id: CCO:I0020241 name: ascc2-cutc physical interaction xref: IntAct:EBI-733922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0026108 ! CUTC_HUMAN [Term] id: CCO:I0020242 name: ascc2-ckap4 physical interaction xref: IntAct:EBI-733925 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005829 ! CKAP4_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN [Term] id: CCO:I0020243 name: ascc2-deaf1 physical interaction xref: IntAct:EBI-733928 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0054631 ! DEAF1_HUMAN [Term] id: CCO:I0020244 name: ascc2-elac2 physical interaction xref: IntAct:EBI-733931 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0063441 ! RNZ2_HUMAN [Term] id: CCO:I0020245 name: ascc2-faf1 physical interaction xref: IntAct:EBI-733934 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0059254 ! FAF1_HUMAN [Term] id: CCO:I0020246 name: ascc2-gfer physical interaction xref: IntAct:EBI-733937 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0042007 ! ALR_HUMAN [Term] id: CCO:I0020247 name: ascc2-igsf9 physical interaction xref: IntAct:EBI-733940 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0063442 ! TUTLA_HUMAN [Term] id: CCO:I0020248 name: ascc2-lpl physical interaction xref: IntAct:EBI-733944 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0063443 ! LIPL_HUMAN [Term] id: CCO:I0020249 name: ascc2-ns physical interaction xref: IntAct:EBI-733947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0016653 ! Q5PU80_HUMAN [Term] id: CCO:I0020250 name: ascc2-pik3cd physical interaction xref: IntAct:EBI-733950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0018352 ! PK3CD_HUMAN [Term] id: CCO:I0020251 name: atp5j2-arl10c physical interaction xref: IntAct:EBI-733977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006324 ! ARL8B_HUMAN relationship: has_participant CCO:B0063395 ! ATPK_HUMAN [Term] id: CCO:I0020252 name: atp5j2-capns1 physical interaction xref: IntAct:EBI-733980 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0063395 ! ATPK_HUMAN [Term] id: CCO:I0020253 name: atp5j2-zfpl1 physical interaction xref: IntAct:EBI-733992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054731 ! ZFPL1_HUMAN relationship: has_participant CCO:B0063395 ! ATPK_HUMAN [Term] id: CCO:I0020254 name: atpif1-chd3 physical interaction xref: IntAct:EBI-733995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063444 ! ATIF1_HUMAN [Term] id: CCO:I0020255 name: baiap2-c14orf1 physical interaction xref: IntAct:EBI-734003 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006287 ! ERG28_HUMAN relationship: has_participant CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:I0020256 name: bcar1-efs physical interaction xref: IntAct:EBI-734015 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0028938 ! EFS_HUMAN [Term] id: CCO:I0020257 name: blmh-trio physical interaction xref: IntAct:EBI-734018 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054681 ! TRIO_HUMAN relationship: has_participant CCO:B0063445 ! BLMH_HUMAN [Term] id: CCO:I0020258 name: c11orf1-setdb1 physical interaction xref: IntAct:EBI-734051 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063446 ! CK001_HUMAN [Term] id: CCO:I0020259 name: c19orf10-bat3 physical interaction xref: IntAct:EBI-734054 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0058132 ! CS010_HUMAN [Term] id: CCO:I0020260 name: c5orf13-igsf21 physical interaction xref: IntAct:EBI-734069 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006168 ! IGS21_HUMAN relationship: has_participant CCO:B0056159 ! NP311_HUMAN [Term] id: CCO:I0020261 name: c7orf19-med31 physical interaction xref: IntAct:EBI-734075 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0063401 ! ORA2P_HUMAN [Term] id: CCO:I0020262 name: c7orf20-prkcsh physical interaction xref: IntAct:EBI-734081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006174 ! CG020_HUMAN relationship: has_participant CCO:B0006228 ! GLU2B_HUMAN [Term] id: CCO:I0020263 name: c9orf25-pola2 physical interaction xref: IntAct:EBI-734090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0063447 ! CI025_HUMAN [Term] id: CCO:I0020264 name: ca8-lrch4 physical interaction xref: IntAct:EBI-734096 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054634 ! LRCH4_HUMAN relationship: has_participant CCO:B0055278 ! CAH8_HUMAN [Term] id: CCO:I0020265 name: cacnb4-tbl3 physical interaction xref: IntAct:EBI-734099 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006176 ! CACB4_HUMAN relationship: has_participant CCO:B0006309 ! TBL3_HUMAN [Term] id: CCO:I0020266 name: capzb-mrpl20 physical interaction xref: IntAct:EBI-734108 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006125 ! CAPZB_HUMAN relationship: has_participant CCO:B0006248 ! RM20_HUMAN [Term] id: CCO:I0020267 name: carhsp1-stc2 physical interaction xref: IntAct:EBI-734111 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006237 ! STC2_HUMAN relationship: has_participant CCO:B0021340 ! CHSP1_HUMAN [Term] id: CCO:I0020268 name: casp6-chd3 physical interaction xref: IntAct:EBI-734114 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0055531 ! CASP6_HUMAN [Term] id: CCO:I0020269 name: ccl7-fez1 physical interaction xref: IntAct:EBI-734123 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0038963 ! CCL7_HUMAN [Term] id: CCO:I0020270 name: cct3-eif2b2 physical interaction xref: IntAct:EBI-734126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005253 ! TCPG_HUMAN relationship: has_participant CCO:B0055434 ! EI2BB_HUMAN [Term] id: CCO:I0020271 name: cct5-tbc1d17 physical interaction xref: IntAct:EBI-734129 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0005291 ! TCPE_HUMAN [Term] id: CCO:I0020272 name: cdk5rap2-stard9 physical interaction xref: IntAct:EBI-734141 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN relationship: has_participant CCO:B0063448 ! STAR9_HUMAN [Term] id: CCO:I0020273 name: celsr1-psap physical interaction xref: IntAct:EBI-734155 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058968 ! CELR1_HUMAN relationship: has_participant CCO:B0063292 ! SAP_HUMAN [Term] id: CCO:I0020274 name: centa2-eef1g physical interaction xref: IntAct:EBI-734158 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0058850 ! CENA2_HUMAN [Term] id: CCO:I0020275 name: chn1-gtf3c1 physical interaction xref: IntAct:EBI-734170 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006211 ! TF3C1_HUMAN relationship: has_participant CCO:B0055044 ! CHIN_HUMAN [Term] id: CCO:I0020276 name: chn1-rps3a physical interaction xref: IntAct:EBI-734173 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0055044 ! CHIN_HUMAN [Term] id: CCO:I0020277 name: cpe-robo2 physical interaction xref: IntAct:EBI-734194 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006081 ! CBPE_HUMAN relationship: has_participant CCO:B0058810 ! ROBO2_HUMAN [Term] id: CCO:I0020278 name: cse1l-hnrpl physical interaction xref: IntAct:EBI-734206 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0006275 ! HNRPL_HUMAN [Term] id: CCO:I0020279 name: cutl1-elac2 physical interaction xref: IntAct:EBI-734218 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040687 ! CUX1_HUMAN relationship: has_participant CCO:B0063441 ! RNZ2_HUMAN [Term] id: CCO:I0020280 name: cutl1-recql5 physical interaction xref: IntAct:EBI-734221 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN relationship: has_participant CCO:B0040687 ! CUX1_HUMAN [Term] id: CCO:I0020281 name: csde1-itm1 physical interaction xref: IntAct:EBI-734230 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054648 ! CSDE1_HUMAN relationship: has_participant CCO:B0063449 ! STT3A_HUMAN [Term] id: CCO:I0020282 name: dap-setdb1 physical interaction xref: IntAct:EBI-734233 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0055463 ! DAP1_HUMAN [Term] id: CCO:I0020283 name: dc6-mcm3ap physical interaction xref: IntAct:EBI-734236 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054547 ! MCM3A_HUMAN relationship: has_participant CCO:B0058843 ! ENY2_HUMAN [Term] id: CCO:I0020284 name: ddr1-wdr57 physical interaction xref: IntAct:EBI-734239 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005996 ! WDR57_HUMAN relationship: has_participant CCO:B0006158 ! DDR1_HUMAN [Term] id: CCO:I0020285 name: ddx24-dnmt2 physical interaction xref: IntAct:EBI-734254 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN relationship: has_participant CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:I0020286 name: ddx24-eif3s6 physical interaction xref: IntAct:EBI-734257 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006183 ! DDX24_HUMAN relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:I0020287 name: ddx24-hspcb physical interaction xref: IntAct:EBI-734263 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0006183 ! DDX24_HUMAN [Term] id: CCO:I0020288 name: ddx24-itgb3bp physical interaction xref: IntAct:EBI-734266 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006183 ! DDX24_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN [Term] id: CCO:I0020289 name: dgkd-hs1bp1 physical interaction xref: IntAct:EBI-734287 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056176 ! DGKD_HUMAN relationship: has_participant CCO:B0062934 ! HAX1_HUMAN [Term] id: CCO:I0020290 name: dgkd-igsf21 physical interaction xref: IntAct:EBI-734290 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006168 ! IGS21_HUMAN relationship: has_participant CCO:B0056176 ! DGKD_HUMAN [Term] id: CCO:I0020291 name: dhx34-pola2 physical interaction xref: IntAct:EBI-734293 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0063450 ! DHX34_HUMAN [Term] id: CCO:I0020292 name: dkfzp434d1428-chd3 physical interaction xref: IntAct:EBI-734299 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063451 ! Q9H0E4_HUMAN [Term] id: CCO:I0020293 name: dncl1-dncl1 physical interaction xref: IntAct:EBI-734356 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006226 ! DYL1_HUMAN [Term] id: CCO:I0020294 name: dnm1-asb13 physical interaction xref: IntAct:EBI-734359 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022139 ! DYN1_HUMAN relationship: has_participant CCO:B0058029 ! ASB13_HUMAN [Term] id: CCO:I0020295 name: dnmt1-rfp physical interaction xref: IntAct:EBI-734368 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005981 ! TRI27_HUMAN relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN [Term] id: CCO:I0020296 name: dpysl4-sh3gl3 physical interaction xref: IntAct:EBI-734380 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063452 ! DPYL4_HUMAN [Term] id: CCO:I0020297 name: drg1-capns1 physical interaction xref: IntAct:EBI-734383 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0063453 ! DRG1_HUMAN [Term] id: CCO:I0020298 name: eef1d-cd48 physical interaction xref: IntAct:EBI-734400 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021069 ! EF1D_HUMAN relationship: has_participant CCO:B0063454 ! CD48_HUMAN [Term] id: CCO:I0020299 name: egr2-acp5 physical interaction xref: IntAct:EBI-734412 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006070 ! EGR2_HUMAN relationship: has_participant CCO:B0063418 ! PPA5_HUMAN [Term] id: CCO:I0020300 name: eif2b3-stc2 physical interaction xref: IntAct:EBI-734415 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005834 ! EI2BG_HUMAN relationship: has_participant CCO:B0006237 ! STC2_HUMAN [Term] id: CCO:I0020301 name: eif3s6-hap1 physical interaction xref: IntAct:EBI-734421 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:I0020302 name: eno2-hsf1 physical interaction xref: IntAct:EBI-734427 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006270 ! ENOG_HUMAN relationship: has_participant CCO:B0026467 ! HSF1_HUMAN [Term] id: CCO:I0020303 name: eno2-sigirr physical interaction xref: IntAct:EBI-734439 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006270 ! ENOG_HUMAN relationship: has_participant CCO:B0056756 ! SIGIR_HUMAN [Term] id: CCO:I0020304 name: epb49-procr physical interaction xref: IntAct:EBI-734445 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055791 ! DEMA_HUMAN relationship: has_participant CCO:B0063455 ! EPCR_HUMAN [Term] id: CCO:I0020305 name: eps8-dnali1 physical interaction xref: IntAct:EBI-734448 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0063174 ! IDLC_HUMAN [Term] id: CCO:I0020306 name: ezh2-wsb2 physical interaction xref: IntAct:EBI-734469 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043441 ! EZH2_HUMAN relationship: has_participant CCO:B0058971 ! WSB2_HUMAN [Term] id: CCO:I0020307 name: f10-prkab1 physical interaction xref: IntAct:EBI-734472 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059353 ! AAKB1_HUMAN relationship: has_participant CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:I0020308 name: fbl-tbc1d17 physical interaction xref: IntAct:EBI-734478 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0005722 ! FBRL_HUMAN [Term] id: CCO:I0020309 name: fbp2-chd3 physical interaction xref: IntAct:EBI-734481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0043612 ! F16P2_HUMAN [Term] id: CCO:I0020310 name: fgfr3-c1orf16 physical interaction xref: IntAct:EBI-734496 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0058061 ! SMG7_HUMAN [Term] id: CCO:I0020311 name: fgfr3-q96lx7 physical interaction xref: IntAct:EBI-734502 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0063457 ! CCD17_HUMAN [Term] id: CCO:I0020312 name: fgfr3-hbz physical interaction xref: IntAct:EBI-734505 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0063458 ! HBAZ_HUMAN [Term] id: CCO:I0020313 name: fgfr3-hnrpl physical interaction xref: IntAct:EBI-734508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0006275 ! HNRPL_HUMAN [Term] id: CCO:I0020314 name: fgfr3-ndufs6 physical interaction xref: IntAct:EBI-734511 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0021658 ! NDUS6_HUMAN [Term] id: CCO:I0020315 name: fgfr3-rnf130 physical interaction xref: IntAct:EBI-734514 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0063459 ! GOLI_HUMAN [Term] id: CCO:I0020316 name: p34-eif3s8 physical interaction xref: IntAct:EBI-734535 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026271 ! EIF3C_HUMAN relationship: has_participant CCO:B0063460 ! P34_HUMAN [Term] id: CCO:I0020317 name: flj21945-med31 physical interaction xref: IntAct:EBI-734575 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0063461 ! CB044_HUMAN [Term] id: CCO:I0020318 name: c15orf29-myst2 physical interaction xref: IntAct:EBI-734581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0063462 ! CO029_HUMAN [Term] id: CCO:I0020319 name: fmnl1-g22p1 physical interaction xref: IntAct:EBI-734616 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0063463 ! FMNL_HUMAN [Term] id: CCO:I0020320 name: ftl-map3k12 physical interaction xref: IntAct:EBI-734619 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006192 ! FRIL_HUMAN relationship: has_participant CCO:B0018778 ! M3K12_HUMAN [Term] id: CCO:I0020321 name: ftl-taf10 physical interaction xref: IntAct:EBI-734622 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0006192 ! FRIL_HUMAN [Term] id: CCO:I0020322 name: fubp1-cugbp1 physical interaction xref: IntAct:EBI-734631 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006265 ! CELF1_HUMAN relationship: has_participant CCO:B0058151 ! FUBP1_HUMAN [Term] id: CCO:I0020323 name: fxyd6-rfp physical interaction xref: IntAct:EBI-734640 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005981 ! TRI27_HUMAN relationship: has_participant CCO:B0006141 ! FXYD6_HUMAN [Term] id: CCO:I0020324 name: gnb5-mvd physical interaction xref: IntAct:EBI-734667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006142 ! GBB5_HUMAN relationship: has_participant CCO:B0025709 ! ERG19_HUMAN [Term] id: CCO:I0020325 name: gng11-zhx1 physical interaction xref: IntAct:EBI-734670 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0055614 ! GBG11_HUMAN [Term] id: CCO:I0020326 name: golph2-eif3s1 physical interaction xref: IntAct:EBI-734682 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006331 ! GOLM1_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0020327 name: golph2-surf5 physical interaction xref: IntAct:EBI-734694 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0006331 ! GOLM1_HUMAN [Term] id: CCO:I0020328 name: gpaa1-eif3s6 physical interaction xref: IntAct:EBI-734703 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006273 ! GPAA1_HUMAN relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN [Term] id: CCO:I0020329 name: hbb-selt physical interaction xref: IntAct:EBI-734742 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055617 ! SELT_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN [Term] id: CCO:I0020330 name: hbxip-maf1 physical interaction xref: IntAct:EBI-734745 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005301 ! MAF1_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN [Term] id: CCO:I0020331 name: herpud1-rpa2 physical interaction xref: IntAct:EBI-734754 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0026851 ! HERP1_HUMAN [Term] id: CCO:I0020332 name: hspb3-anp32a physical interaction xref: IntAct:EBI-734793 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006073 ! AN32A_HUMAN relationship: has_participant CCO:B0006197 ! HSPB3_HUMAN [Term] id: CCO:I0020333 name: hspb3-med31 physical interaction xref: IntAct:EBI-734796 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0006197 ! HSPB3_HUMAN [Term] id: CCO:I0020334 name: hspb3-med8 physical interaction xref: IntAct:EBI-734808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0006197 ! HSPB3_HUMAN [Term] id: CCO:I0020335 name: hspb3-ramp3 physical interaction xref: IntAct:EBI-734817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006197 ! HSPB3_HUMAN relationship: has_participant CCO:B0049915 ! RAMP3_HUMAN [Term] id: CCO:I0020336 name: hsph1-chd3 physical interaction xref: IntAct:EBI-734823 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063092 ! HS105_HUMAN [Term] id: CCO:I0020337 name: htatsf1-fez1 physical interaction xref: IntAct:EBI-734832 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005393 ! FEZ1_HUMAN relationship: has_participant CCO:B0054514 ! HTSF1_HUMAN [Term] id: CCO:I0020338 name: id2-dkfzp564o0523 physical interaction xref: IntAct:EBI-734835 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006149 ! ID2_HUMAN relationship: has_participant CCO:B0061993 ! CG064_HUMAN [Term] id: CCO:I0020339 name: igfbp3-pola2 physical interaction xref: IntAct:EBI-734838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN [Term] id: CCO:I0020340 name: igfbp5-bat3 physical interaction xref: IntAct:EBI-734841 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0055174 ! IBP5_HUMAN [Term] id: CCO:I0020341 name: igsf2-sfrs5 physical interaction xref: IntAct:EBI-734844 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031760 ! SFRS5_HUMAN relationship: has_participant CCO:B0058120 ! IGSF2_HUMAN [Term] id: CCO:I0020342 name: igsf2-sh3gl3 physical interaction xref: IntAct:EBI-734847 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0058120 ! IGSF2_HUMAN [Term] id: CCO:I0020343 name: igsf2-st13 physical interaction xref: IntAct:EBI-734850 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058120 ! IGSF2_HUMAN relationship: has_participant CCO:B0063106 ! F10A1_HUMAN [Term] id: CCO:I0020344 name: il6-sh3gl2 physical interaction xref: IntAct:EBI-734853 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN [Term] id: CCO:I0020345 name: itgb3bp-abcf1 physical interaction xref: IntAct:EBI-734862 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063464 ! ABCF1_HUMAN [Term] id: CCO:I0020346 name: itgb3bp-akt1s1 physical interaction xref: IntAct:EBI-734865 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:I0020347 name: itgb3bp-flj20534 physical interaction xref: IntAct:EBI-734868 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063465 ! CD027_HUMAN [Term] id: CCO:I0020348 name: itgb3bp-mrps31 physical interaction xref: IntAct:EBI-734871 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063466 ! RT31_HUMAN [Term] id: CCO:I0020349 name: itgb3bp-ofd1 physical interaction xref: IntAct:EBI-734874 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063467 ! OFD1_HUMAN [Term] id: CCO:I0020350 name: itgb3bp-usp33 physical interaction xref: IntAct:EBI-734878 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063468 ! UBP33_HUMAN [Term] id: CCO:I0020351 name: itgb3bp-wfs1 physical interaction xref: IntAct:EBI-734881 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0054687 ! WFS1_HUMAN [Term] id: CCO:I0020352 name: itsn1-smarcc2 physical interaction xref: IntAct:EBI-734884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN [Term] id: CCO:I0020353 name: kcnh2-ndufs6 physical interaction xref: IntAct:EBI-734899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021658 ! NDUS6_HUMAN relationship: has_participant CCO:B0055844 ! KCNH2_HUMAN [Term] id: CCO:I0020354 name: kiaa1229-erbb3 physical interaction xref: IntAct:EBI-734917 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0063469 ! ODF2L_HUMAN [Term] id: CCO:I0020355 name: krt9-sh3gl3 physical interaction xref: IntAct:EBI-734935 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005922 ! K1C9_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN [Term] id: CCO:I0020356 name: l1cam-pea15 physical interaction xref: IntAct:EBI-734938 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0029795 ! L1CAM_HUMAN relationship: has_participant CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:I0020357 name: tinagl1-med31 physical interaction xref: IntAct:EBI-734947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0027449 ! TINAL_HUMAN [Term] id: CCO:I0020358 name: lgals4-arpc3 physical interaction xref: IntAct:EBI-734950 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN relationship: has_participant CCO:B0062984 ! LEG4_HUMAN [Term] id: CCO:I0020359 name: luc7l2-pea15 physical interaction xref: IntAct:EBI-735019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN relationship: has_participant CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:I0020360 name: lypla2-scmh1 physical interaction xref: IntAct:EBI-735025 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006282 ! LYPA2_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:I0020361 name: maff-psap physical interaction xref: IntAct:EBI-735034 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0042180 ! MAFF_HUMAN relationship: has_participant CCO:B0063292 ! SAP_HUMAN [Term] id: CCO:I0020362 name: maged1-brp44l physical interaction xref: IntAct:EBI-735037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0063470 ! BR44L_HUMAN [Term] id: CCO:I0020363 name: mapk9-xpnpep1 physical interaction xref: IntAct:EBI-735049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006347 ! XPP1_HUMAN relationship: has_participant CCO:B0026769 ! MK09_HUMAN [Term] id: CCO:I0020364 name: mapk9-xpo7 physical interaction xref: IntAct:EBI-735052 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005665 ! XPO7_HUMAN relationship: has_participant CCO:B0026769 ! MK09_HUMAN [Term] id: CCO:I0020365 name: mcoln1-rfp physical interaction xref: IntAct:EBI-735073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005981 ! TRI27_HUMAN relationship: has_participant CCO:B0028808 ! MCLN1_HUMAN [Term] id: CCO:I0020366 name: mdh2-wars physical interaction xref: IntAct:EBI-735079 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021811 ! SYWC_HUMAN relationship: has_participant CCO:B0030700 ! MDHM_HUMAN [Term] id: CCO:I0020367 name: mgc:13379-mcm3ap physical interaction xref: IntAct:EBI-735082 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054547 ! MCM3A_HUMAN relationship: has_participant CCO:B0063471 ! TM216_HUMAN [Term] id: CCO:I0020368 name: mgc3731-sod2 physical interaction xref: IntAct:EBI-735103 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006336 ! NOL12_HUMAN relationship: has_participant CCO:B0033778 ! SODM_HUMAN [Term] id: CCO:I0020369 name: mgc45871-htatip physical interaction xref: IntAct:EBI-735106 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0063472 ! F101B_HUMAN [Term] id: CCO:I0020370 name: mpp3-c4orf14 physical interaction xref: IntAct:EBI-735142 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0026813 ! CD014_HUMAN [Term] id: CCO:I0020371 name: mpp3-gng7 physical interaction xref: IntAct:EBI-735145 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0054537 ! GBG7_HUMAN [Term] id: CCO:I0020372 name: mpp3-mdh1 physical interaction xref: IntAct:EBI-735148 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063181 ! MDHC_HUMAN [Term] id: CCO:I0020373 name: mpp3-mgc16597 physical interaction xref: IntAct:EBI-735151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063473 ! CC137_HUMAN [Term] id: CCO:I0020374 name: mpp3-rps2 physical interaction xref: IntAct:EBI-735157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063474 ! RS2_HUMAN [Term] id: CCO:I0020375 name: ms4a7-hmgcl physical interaction xref: IntAct:EBI-735175 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025401 ! MS4A7_HUMAN relationship: has_participant CCO:B0063475 ! HMGCL_HUMAN [Term] id: CCO:I0020376 name: muf1-myo9b physical interaction xref: IntAct:EBI-735178 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031122 ! MYO9B_HUMAN relationship: has_participant CCO:B0043602 ! LRC41_HUMAN [Term] id: CCO:I0020377 name: mycbp-cfl1 physical interaction xref: IntAct:EBI-735184 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN [Term] id: CCO:I0020378 name: mycbp-kiaa1337 physical interaction xref: IntAct:EBI-735190 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN relationship: has_participant CCO:B0063476 ! PTHD2_HUMAN [Term] id: CCO:I0020379 name: mycbp-ssrp1 physical interaction xref: IntAct:EBI-735193 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN [Term] id: CCO:I0020380 name: nap1l1-nap1l1 physical interaction xref: IntAct:EBI-735196 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN [Term] id: CCO:I0020381 name: ndufa7-prkab1 physical interaction xref: IntAct:EBI-735202 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059353 ! AAKB1_HUMAN relationship: has_participant CCO:B0063477 ! NDUA7_HUMAN [Term] id: CCO:I0020382 name: ndufb9-gdf9 physical interaction xref: IntAct:EBI-735211 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0063423 ! NDUB9_HUMAN [Term] id: CCO:I0020383 name: ndufv2-sp110 physical interaction xref: IntAct:EBI-735214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058777 ! SP110_HUMAN relationship: has_participant CCO:B0063424 ! NDUV2_HUMAN [Term] id: CCO:I0020384 name: notch1-g22p1 physical interaction xref: IntAct:EBI-735229 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN [Term] id: CCO:I0020385 name: nr4a1-fxyd3 physical interaction xref: IntAct:EBI-735235 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055150 ! NR4A1_HUMAN relationship: has_participant CCO:B0063478 ! FXYD3_HUMAN [Term] id: CCO:I0020386 name: nsf-eif3s6 physical interaction xref: IntAct:EBI-735241 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN relationship: has_participant CCO:B0038850 ! NSF_HUMAN [Term] id: CCO:I0020387 name: nudt3-asb13 physical interaction xref: IntAct:EBI-735256 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026419 ! NUDT3_HUMAN relationship: has_participant CCO:B0058029 ! ASB13_HUMAN [Term] id: CCO:I0020388 name: nudt3-rab17 physical interaction xref: IntAct:EBI-735259 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026419 ! NUDT3_HUMAN relationship: has_participant CCO:B0058657 ! RAB17_HUMAN [Term] id: CCO:I0020389 name: nudt5-mcm3ap physical interaction xref: IntAct:EBI-735262 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054547 ! MCM3A_HUMAN relationship: has_participant CCO:B0063479 ! NUDT5_HUMAN [Term] id: CCO:I0020390 name: nup62-ik physical interaction xref: IntAct:EBI-735265 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006239 ! RED_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN [Term] id: CCO:I0020391 name: bles03-sh3gl3 physical interaction xref: IntAct:EBI-735288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0062895 ! CK068_HUMAN [Term] id: CCO:I0020392 name: pacsin1-myst2 physical interaction xref: IntAct:EBI-735291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0063480 ! PACN1_HUMAN [Term] id: CCO:I0020393 name: pafah1b2-acin1 physical interaction xref: IntAct:EBI-735294 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006291 ! PA1B2_HUMAN relationship: has_participant CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:I0020394 name: pafah1b2-zfp36l1 physical interaction xref: IntAct:EBI-735312 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006291 ! PA1B2_HUMAN relationship: has_participant CCO:B0026498 ! TISB_HUMAN [Term] id: CCO:I0020395 name: park2-rac1 physical interaction xref: IntAct:EBI-735318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0006227 ! PRKN2_HUMAN [Term] id: CCO:I0020396 name: pcmt1-chd3 physical interaction xref: IntAct:EBI-735324 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0062985 ! PIMT_HUMAN [Term] id: CCO:I0020397 name: pex14-med8 physical interaction xref: IntAct:EBI-735327 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0054627 ! PEX14_HUMAN [Term] id: CCO:I0020398 name: pex14-zhx1 physical interaction xref: IntAct:EBI-735330 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0054627 ! PEX14_HUMAN [Term] id: CCO:I0020399 name: pgam1-g22p1 physical interaction xref: IntAct:EBI-735333 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0006323 ! PGAM1_HUMAN [Term] id: CCO:I0020400 name: phf10-aplp1 physical interaction xref: IntAct:EBI-735345 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006179 ! APLP1_HUMAN relationship: has_participant CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:I0020401 name: phyhip-hdac11 physical interaction xref: IntAct:EBI-735351 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005701 ! HDA11_HUMAN relationship: has_participant CCO:B0006241 ! PHYIP_HUMAN [Term] id: CCO:I0020402 name: phyhip-ppie physical interaction xref: IntAct:EBI-735369 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006241 ! PHYIP_HUMAN relationship: has_participant CCO:B0059255 ! PPIE_HUMAN [Term] id: CCO:I0020403 name: phyhip-smarcc2 physical interaction xref: IntAct:EBI-735378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0006241 ! PHYIP_HUMAN [Term] id: CCO:I0020404 name: pigc-zhx1 physical interaction xref: IntAct:EBI-735384 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0063481 ! PIGC_HUMAN [Term] id: CCO:I0020405 name: polr3f-c14orf150 physical interaction xref: IntAct:EBI-735411 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006101 ! RPC6_HUMAN relationship: has_participant CCO:B0063482 ! WDR89_HUMAN [Term] id: CCO:I0020406 name: polr3f-prpf4b physical interaction xref: IntAct:EBI-735414 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006101 ! RPC6_HUMAN relationship: has_participant CCO:B0027516 ! PRP4B_HUMAN [Term] id: CCO:I0020407 name: ppp1r1b-dlgap4 physical interaction xref: IntAct:EBI-735447 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006307 ! DLGP4_HUMAN relationship: has_participant CCO:B0059099 ! PPR1B_HUMAN [Term] id: CCO:I0020408 name: ppp1r8-crmp1 physical interaction xref: IntAct:EBI-735450 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:I0020409 name: ppp1r8-setdb1 physical interaction xref: IntAct:EBI-735453 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0055860 ! PP1R8_HUMAN [Term] id: CCO:I0020410 name: pqbp1-c14orf1 physical interaction xref: IntAct:EBI-735456 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0020411 name: prei3-fadd physical interaction xref: IntAct:EBI-735465 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0020412 name: prei3-mgc5309 physical interaction xref: IntAct:EBI-735468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0020413 name: prnp-bat3 physical interaction xref: IntAct:EBI-735477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0043436 ! PRIO_HUMAN [Term] id: CCO:I0020414 name: ptov1-epb49 physical interaction xref: IntAct:EBI-735504 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006294 ! PTOV1_HUMAN relationship: has_participant CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:I0020415 name: ptov1-sptan1 physical interaction xref: IntAct:EBI-735510 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006294 ! PTOV1_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN [Term] id: CCO:I0020416 name: pwp2h-tom1l1 physical interaction xref: IntAct:EBI-735524 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006203 ! TM1L1_HUMAN relationship: has_participant CCO:B0056050 ! PWP2_HUMAN [Term] id: CCO:I0020417 name: rab11b-srebf2 physical interaction xref: IntAct:EBI-735527 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0038434 ! RB11B_HUMAN relationship: has_participant CCO:B0049934 ! SRBP2_HUMAN [Term] id: CCO:I0020418 name: rab18-pde6d physical interaction xref: IntAct:EBI-735530 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006130 ! PDE6D_HUMAN relationship: has_participant CCO:B0058836 ! RAB18_HUMAN [Term] id: CCO:I0020419 name: rab1a-q86tw2 physical interaction xref: IntAct:EBI-735533 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0038785 ! ADCK1_HUMAN [Term] id: CCO:I0020420 name: rab1a-capns1 physical interaction xref: IntAct:EBI-735536 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN [Term] id: CCO:I0020421 name: rab1a-creb1 physical interaction xref: IntAct:EBI-735539 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN [Term] id: CCO:I0020422 name: rab1a-fscn1 physical interaction xref: IntAct:EBI-735542 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0056170 ! FSCN1_HUMAN [Term] id: CCO:I0020423 name: rab1a-hivep1 physical interaction xref: IntAct:EBI-735545 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0020424 name: rab1a-slc16a8 physical interaction xref: IntAct:EBI-735548 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0051475 ! MOT3_HUMAN [Term] id: CCO:I0020425 name: rab1a-tbc1d17 physical interaction xref: IntAct:EBI-735551 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN [Term] id: CCO:I0020426 name: rab27a-eef1a1 physical interaction xref: IntAct:EBI-735554 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005831 ! EF1A1_HUMAN relationship: has_participant CCO:B0006223 ! RB27A_HUMAN [Term] id: CCO:I0020427 name: rab35-cbr3 physical interaction xref: IntAct:EBI-735563 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056054 ! RAB35_HUMAN relationship: has_participant CCO:B0063483 ! CBR3_HUMAN [Term] id: CCO:I0020428 name: rab35-tbpl1 physical interaction xref: IntAct:EBI-735566 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055618 ! TBPL1_HUMAN relationship: has_participant CCO:B0056054 ! RAB35_HUMAN [Term] id: CCO:I0020429 name: rab8a-bat3 physical interaction xref: IntAct:EBI-735572 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0032548 ! RAB8A_HUMAN [Term] id: CCO:I0020430 name: rabif-hbxip physical interaction xref: IntAct:EBI-735575 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN relationship: has_participant CCO:B0055383 ! MSS4_HUMAN [Term] id: CCO:I0020431 name: rap1ga1-pfn2 physical interaction xref: IntAct:EBI-735581 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0055384 ! RPGP1_HUMAN [Term] id: CCO:I0020432 name: rdbp-vamp3 physical interaction xref: IntAct:EBI-735590 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0030751 ! VAMP3_HUMAN relationship: has_participant CCO:B0055102 ! NELFE_HUMAN [Term] id: CCO:I0020433 name: recql5-itgb3bp physical interaction xref: IntAct:EBI-735596 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN [Term] id: CCO:I0020434 name: recql5-mapk8ip1 physical interaction xref: IntAct:EBI-735599 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN relationship: has_participant CCO:B0059280 ! JIP1_HUMAN [Term] id: CCO:I0020435 name: rgs1-map3k12 physical interaction xref: IntAct:EBI-735608 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018778 ! M3K12_HUMAN relationship: has_participant CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:I0020436 name: rgs1-utp14a physical interaction xref: IntAct:EBI-735611 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006134 ! UT14A_HUMAN relationship: has_participant CCO:B0020780 ! RGS1_HUMAN [Term] id: CCO:I0020437 name: ripx-unc119 physical interaction xref: IntAct:EBI-735626 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033364 ! RUFY3_HUMAN relationship: has_participant CCO:B0043869 ! U119A_HUMAN [Term] id: CCO:I0020438 name: rnf146-pfn2 physical interaction xref: IntAct:EBI-735629 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0063484 ! RN146_HUMAN [Term] id: CCO:I0020439 name: rnf2-cbx4 physical interaction xref: IntAct:EBI-735632 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020552 ! RING2_HUMAN relationship: has_participant CCO:B0054304 ! CBX4_HUMAN [Term] id: CCO:I0020440 name: rpa2-acp5 physical interaction xref: IntAct:EBI-735642 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0063418 ! PPA5_HUMAN [Term] id: CCO:I0020441 name: rpl10-tbpl1 physical interaction xref: IntAct:EBI-735645 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055618 ! TBPL1_HUMAN relationship: has_participant CCO:B0063093 ! RL10_HUMAN [Term] id: CCO:I0020442 name: rps6ka6-nr4a1 physical interaction xref: IntAct:EBI-735672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028620 ! KS6A6_HUMAN relationship: has_participant CCO:B0055150 ! NR4A1_HUMAN [Term] id: CCO:I0020443 name: rras2-lgals4 physical interaction xref: IntAct:EBI-735675 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN relationship: has_participant CCO:B0062984 ! LEG4_HUMAN [Term] id: CCO:I0020444 name: rtn4-crmp1 physical interaction xref: IntAct:EBI-735678 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0041735 ! RTN4_HUMAN [Term] id: CCO:I0020445 name: ruvbl2-fdft1 physical interaction xref: IntAct:EBI-735708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0027270 ! FDFT_HUMAN [Term] id: CCO:I0020446 name: s100a10-cops6 physical interaction xref: IntAct:EBI-735711 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0055600 ! S10AA_HUMAN [Term] id: CCO:I0020447 name: s100a8-hrmt1l2 physical interaction xref: IntAct:EBI-735717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0006159 ! S10A8_HUMAN [Term] id: CCO:I0020448 name: safb2-chgb physical interaction xref: IntAct:EBI-735726 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006217 ! SCG1_HUMAN relationship: has_participant CCO:B0055964 ! SAFB2_HUMAN [Term] id: CCO:I0020449 name: atxn2-chgb physical interaction xref: IntAct:EBI-735745 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006217 ! SCG1_HUMAN [Term] id: CCO:I0020450 name: scmh1-scmh1 physical interaction xref: IntAct:EBI-735751 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:I0020451 name: serf2-chd3 physical interaction xref: IntAct:EBI-735760 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0043420 ! SERF2_HUMAN [Term] id: CCO:I0020452 name: serpina5-cops6 physical interaction xref: IntAct:EBI-735763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0014899 ! IPSP_HUMAN [Term] id: CCO:I0020453 name: slc38a3-setdb1 physical interaction xref: IntAct:EBI-735799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063485 ! S38A3_HUMAN [Term] id: CCO:I0020454 name: sumo2-maf1 physical interaction xref: IntAct:EBI-735802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005301 ! MAF1_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0020455 name: snap25-loc112476 physical interaction xref: IntAct:EBI-735805 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055598 ! SNP25_HUMAN relationship: has_participant CCO:B0063486 ! PRRT2_HUMAN [Term] id: CCO:I0020456 name: snapap-lamc1 physical interaction xref: IntAct:EBI-735808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043870 ! SNAPN_HUMAN relationship: has_participant CCO:B0054985 ! LAMC1_HUMAN [Term] id: CCO:I0020457 name: sncaip-c7orf20 physical interaction xref: IntAct:EBI-735811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006174 ! CG020_HUMAN relationship: has_participant CCO:B0006235 ! SNCAP_HUMAN [Term] id: CCO:I0020458 name: sncaip-sh2d3c physical interaction xref: IntAct:EBI-735814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006235 ! SNCAP_HUMAN relationship: has_participant CCO:B0063487 ! Q5JU30_HUMAN [Term] id: CCO:I0020459 name: sptan1-pin4 physical interaction xref: IntAct:EBI-735824 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN relationship: has_participant CCO:B0063394 ! PIN4_HUMAN [Term] id: CCO:I0020460 name: stmn4-immt physical interaction xref: IntAct:EBI-735884 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006201 ! IMMT_HUMAN relationship: has_participant CCO:B0023038 ! STMN4_HUMAN [Term] id: CCO:I0020461 name: strn4-ak5 physical interaction xref: IntAct:EBI-735890 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063488 ! KAD5_HUMAN [Term] id: CCO:I0020462 name: strn4-bat1 physical interaction xref: IntAct:EBI-735896 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005899 ! UAP56_HUMAN relationship: has_participant CCO:B0006352 ! STRN4_HUMAN [Term] id: CCO:I0020463 name: strn4-cldn12 physical interaction xref: IntAct:EBI-735899 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063489 ! CLD12_HUMAN [Term] id: CCO:I0020464 name: strn4-gdf9 physical interaction xref: IntAct:EBI-735902 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0006352 ! STRN4_HUMAN [Term] id: CCO:I0020465 name: strn4-nbea physical interaction xref: IntAct:EBI-735905 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063490 ! NBEA_HUMAN [Term] id: CCO:I0020466 name: strn4-pik4ca physical interaction xref: IntAct:EBI-735908 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0055350 ! PI4KA_HUMAN [Term] id: CCO:I0020467 name: strn4-slc25a6 physical interaction xref: IntAct:EBI-735914 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063075 ! ADT3_HUMAN [Term] id: CCO:I0020468 name: strn4-sprn physical interaction xref: IntAct:EBI-735917 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063491 ! SPRN_HUMAN [Term] id: CCO:I0020469 name: svil-luc7l2 physical interaction xref: IntAct:EBI-735947 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006150 ! LC7L2_HUMAN relationship: has_participant CCO:B0054762 ! SVIL_HUMAN [Term] id: CCO:I0020470 name: tcea2-akt1s1 physical interaction xref: IntAct:EBI-735971 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN relationship: has_participant CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:I0020471 name: tcea2-fbf1 physical interaction xref: IntAct:EBI-735977 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN relationship: has_participant CCO:B0063492 ! Q8IZ48_HUMAN [Term] id: CCO:I0020472 name: tcea2-wdr47 physical interaction xref: IntAct:EBI-735983 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN relationship: has_participant CCO:B0006319 ! WDR47_HUMAN [Term] id: CCO:I0020473 name: tcea2-sh3gl2 physical interaction xref: IntAct:EBI-735992 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN [Term] id: CCO:I0020474 name: tcea2-tax1bp3 physical interaction xref: IntAct:EBI-735995 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN relationship: has_participant CCO:B0054390 ! TX1B3_HUMAN [Term] id: CCO:I0020475 name: tcf21-aplp1 physical interaction xref: IntAct:EBI-735998 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006179 ! APLP1_HUMAN relationship: has_participant CCO:B0054510 ! TCF21_HUMAN [Term] id: CCO:I0020476 name: tdgf1-bat3 physical interaction xref: IntAct:EBI-736001 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN [Term] id: CCO:I0020477 name: th1l-arpc4 physical interaction xref: IntAct:EBI-736019 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057376 ! NELFD_HUMAN relationship: has_participant CCO:B0063364 ! ARPC4_HUMAN [Term] id: CCO:I0020478 name: th1l-eprs physical interaction xref: IntAct:EBI-736022 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057376 ! NELFD_HUMAN relationship: has_participant CCO:B0063046 ! SYEP_HUMAN [Term] id: CCO:I0020479 name: th1l-serf2 physical interaction xref: IntAct:EBI-736025 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043420 ! SERF2_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0020480 name: thap8-dncl1 physical interaction xref: IntAct:EBI-736028 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006226 ! DYL1_HUMAN relationship: has_participant CCO:B0006304 ! THAP8_HUMAN [Term] id: CCO:I0020481 name: tm4sf6-chd3 physical interaction xref: IntAct:EBI-736037 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006247 ! Q6IAN9_HUMAN [Term] id: CCO:I0020482 name: tnfrsf10c-apoa1 physical interaction xref: IntAct:EBI-736040 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028600 ! APOA1_HUMAN relationship: has_participant CCO:B0063436 ! TR10C_HUMAN [Term] id: CCO:I0020483 name: tnfrsf6-c14orf1 physical interaction xref: IntAct:EBI-736046 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0006287 ! ERG28_HUMAN [Term] id: CCO:I0020484 name: tnfsf10-acp5 physical interaction xref: IntAct:EBI-736049 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0063418 ! PPA5_HUMAN [Term] id: CCO:I0020485 name: tob1-scmh1 physical interaction xref: IntAct:EBI-736058 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025823 ! TOB1_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:I0020486 name: tob1-setdb1 physical interaction xref: IntAct:EBI-736061 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0025823 ! TOB1_HUMAN [Term] id: CCO:I0020487 name: tomm20-apoa1 physical interaction xref: IntAct:EBI-736073 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006116 ! TOM20_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN [Term] id: CCO:I0020488 name: tp53i3-fundc2 physical interaction xref: IntAct:EBI-736085 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056356 ! QORX_HUMAN relationship: has_participant CCO:B0063393 ! FUND2_HUMAN [Term] id: CCO:I0020489 name: tubb4-insm1 physical interaction xref: IntAct:EBI-736115 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006167 ! TBB4_HUMAN relationship: has_participant CCO:B0055685 ! INSM1_HUMAN [Term] id: CCO:I0020490 name: tubb4-mrpl28 physical interaction xref: IntAct:EBI-736124 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006167 ! TBB4_HUMAN relationship: has_participant CCO:B0055871 ! RM28_HUMAN [Term] id: CCO:I0020491 name: tubb4-robo1 physical interaction xref: IntAct:EBI-736130 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006167 ! TBB4_HUMAN relationship: has_participant CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:I0020492 name: ulk2-pola2 physical interaction xref: IntAct:EBI-736151 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006252 ! ULK2_HUMAN [Term] id: CCO:I0020493 name: umps-cdc42ep3 physical interaction xref: IntAct:EBI-736154 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059193 ! BORG2_HUMAN relationship: has_participant CCO:B0063493 ! PYR5_HUMAN [Term] id: CCO:I0020494 name: usp11-setdb1 physical interaction xref: IntAct:EBI-736157 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063143 ! UBP11_HUMAN [Term] id: CCO:I0020495 name: usp13-dvl1 physical interaction xref: IntAct:EBI-736160 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054363 ! DVL1_HUMAN relationship: has_participant CCO:B0063494 ! UBP13_HUMAN [Term] id: CCO:I0020496 name: xpnpep1-pola2 physical interaction xref: IntAct:EBI-736187 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0006347 ! XPP1_HUMAN [Term] id: CCO:I0020497 name: zfp64-c14orf1 physical interaction xref: IntAct:EBI-736196 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006287 ! ERG28_HUMAN relationship: has_participant CCO:B0037139 ! ZF64A_HUMAN [Term] id: CCO:I0020498 name: znf11b-hap1 physical interaction xref: IntAct:EBI-736199 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006153 ! HAP1_HUMAN relationship: has_participant CCO:B0055773 ! ZN33B_HUMAN [Term] id: CCO:I0020499 name: znf435-flj20551 physical interaction xref: IntAct:EBI-736208 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0049842 ! ZSC16_HUMAN relationship: has_participant CCO:B0063495 ! S2538_HUMAN [Term] id: CCO:I0020500 name: znf594-golga2 physical interaction xref: IntAct:EBI-736214 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006274 ! GOGA2_HUMAN relationship: has_participant CCO:B0058238 ! ZN594_HUMAN [Term] id: CCO:I0020501 name: actr1b-chd3 physical interaction xref: IntAct:EBI-736268 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0063496 ! ACTY_HUMAN [Term] id: CCO:I0020502 name: adpgk-gdf9 physical interaction xref: IntAct:EBI-736271 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0006354 ! ADPGK_HUMAN [Term] id: CCO:I0020503 name: aes-ccl7 physical interaction xref: IntAct:EBI-736274 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005987 ! AES_HUMAN relationship: has_participant CCO:B0038963 ! CCL7_HUMAN [Term] id: CCO:I0020504 name: aes-gabarap physical interaction xref: IntAct:EBI-736277 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005987 ! AES_HUMAN relationship: has_participant CCO:B0006196 ! GBRAP_HUMAN [Term] id: CCO:I0020505 name: aes-rpl18a physical interaction xref: IntAct:EBI-736280 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005987 ! AES_HUMAN relationship: has_participant CCO:B0006300 ! RL18A_HUMAN [Term] id: CCO:I0020506 name: akr1c3-acin1 physical interaction xref: IntAct:EBI-736283 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006117 ! AK1C3_HUMAN relationship: has_participant CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:I0020507 name: arf4l-mgc40499 physical interaction xref: IntAct:EBI-736292 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN relationship: has_participant CCO:B0051192 ! CNPY4_HUMAN [Term] id: CCO:I0020508 name: arhgdia-siat4c physical interaction xref: IntAct:EBI-736295 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN relationship: has_participant CCO:B0063497 ! Q6IBE6_HUMAN [Term] id: CCO:I0020509 name: arhh-kcnh2 physical interaction xref: IntAct:EBI-736298 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006171 ! Q6ICP4_HUMAN relationship: has_participant CCO:B0055844 ! KCNH2_HUMAN [Term] id: CCO:I0020510 name: arpc3-cetp physical interaction xref: IntAct:EBI-736301 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN relationship: has_participant CCO:B0062887 ! CETP_HUMAN [Term] id: CCO:I0020511 name: arpc3-lta4h physical interaction xref: IntAct:EBI-736310 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN relationship: has_participant CCO:B0024129 ! LKHA4_HUMAN [Term] id: CCO:I0020512 name: arr3-rcor2 physical interaction xref: IntAct:EBI-736313 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055311 ! ARRC_HUMAN relationship: has_participant CCO:B0057397 ! RCOR2_HUMAN [Term] id: CCO:I0020513 name: arr3-map2k7 physical interaction xref: IntAct:EBI-736316 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020951 ! MP2K7_HUMAN relationship: has_participant CCO:B0055311 ! ARRC_HUMAN [Term] id: CCO:I0020514 name: arrb2-ndufs7 physical interaction xref: IntAct:EBI-736319 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055250 ! ARRB2_HUMAN relationship: has_participant CCO:B0063498 ! NDUS7_HUMAN [Term] id: CCO:I0020515 name: atp5c1-pawr physical interaction xref: IntAct:EBI-736322 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006122 ! ATPG_HUMAN relationship: has_participant CCO:B0058234 ! PAWR_HUMAN [Term] id: CCO:I0020516 name: atp5c1-znf337 physical interaction xref: IntAct:EBI-736325 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006122 ! ATPG_HUMAN relationship: has_participant CCO:B0059340 ! ZN337_HUMAN [Term] id: CCO:I0020517 name: fra10ac1-map3k12 physical interaction xref: IntAct:EBI-736358 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018778 ! M3K12_HUMAN relationship: has_participant CCO:B0063348 ! F10C1_HUMAN [Term] id: CCO:I0020518 name: c16orf34-g22p1 physical interaction xref: IntAct:EBI-736364 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:I0020519 name: q53yb2-scmh1 physical interaction xref: IntAct:EBI-736367 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN relationship: has_participant CCO:B0063500 ! Q53YB2_HUMAN [Term] id: CCO:I0020520 name: c2f-anxa3 physical interaction xref: IntAct:EBI-736385 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006119 ! ANXA3_HUMAN relationship: has_participant CCO:B0006260 ! NEP1_HUMAN [Term] id: CCO:I0020521 name: c2f-hivep1 physical interaction xref: IntAct:EBI-736394 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006260 ! NEP1_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN [Term] id: CCO:I0020522 name: c3orf6-rps3a physical interaction xref: IntAct:EBI-736406 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0063501 ! CCD50_HUMAN [Term] id: CCO:I0020523 name: c7orf20-sod2 physical interaction xref: IntAct:EBI-736427 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006174 ! CG020_HUMAN relationship: has_participant CCO:B0033778 ! SODM_HUMAN [Term] id: CCO:I0020524 name: c9orf74-tbl3 physical interaction xref: IntAct:EBI-736436 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006309 ! TBL3_HUMAN relationship: has_participant CCO:B0006312 ! URM1_HUMAN [Term] id: CCO:I0020525 name: rp1_69m21_1-mdfi physical interaction xref: IntAct:EBI-736442 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0063502 ! Q9UJD7_HUMAN [Term] id: CCO:I0020526 name: cbr1-ercc8 physical interaction xref: IntAct:EBI-736451 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055887 ! ERCC8_HUMAN relationship: has_participant CCO:B0063371 ! CBR1_HUMAN [Term] id: CCO:I0020527 name: cdk5rap2-nefl physical interaction xref: IntAct:EBI-736466 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN relationship: has_participant CCO:B0006343 ! NFL_HUMAN [Term] id: CCO:I0020528 name: celsr2-klf6 physical interaction xref: IntAct:EBI-736481 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0058431 ! KLF6_HUMAN [Term] id: CCO:I0020529 name: celsr2-gars physical interaction xref: IntAct:EBI-736484 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0038779 ! SYG_HUMAN [Term] id: CCO:I0020530 name: celsr2-phf10 physical interaction xref: IntAct:EBI-736487 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0057976 ! PHF10_HUMAN [Term] id: CCO:I0020531 name: chrnb1-cops6 physical interaction xref: IntAct:EBI-736505 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006133 ! CSN6_HUMAN relationship: has_participant CCO:B0054987 ! ACHB_HUMAN [Term] id: CCO:I0020532 name: ercc8-qp_c physical interaction xref: IntAct:EBI-736508 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055887 ! ERCC8_HUMAN relationship: has_participant CCO:B0063503 ! QCR8_HUMAN [Term] id: CCO:I0020533 name: creb1-hps6 physical interaction xref: IntAct:EBI-736523 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0006286 ! HPS6_HUMAN [Term] id: CCO:I0020534 name: cutl1-ca12 physical interaction xref: IntAct:EBI-736529 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040687 ! CUX1_HUMAN relationship: has_participant CCO:B0063504 ! CAH12_HUMAN [Term] id: CCO:I0020535 name: dazap2-tle1 physical interaction xref: IntAct:EBI-736532 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005180 ! DAZP2_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN [Term] id: CCO:I0020536 name: ddr1-c1orf165 physical interaction xref: IntAct:EBI-736544 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006158 ! DDR1_HUMAN relationship: has_participant CCO:B0062795 ! CA165_HUMAN [Term] id: CCO:I0020537 name: ddx18-inadl physical interaction xref: IntAct:EBI-736550 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0057881 ! INADL_HUMAN relationship: has_participant CCO:B0063505 ! DDX18_HUMAN [Term] id: CCO:I0020538 name: ddx18-mta1 physical interaction xref: IntAct:EBI-736553 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055899 ! MTA1_HUMAN relationship: has_participant CCO:B0063505 ! DDX18_HUMAN [Term] id: CCO:I0020539 name: ddx24-c11orf15 physical interaction xref: IntAct:EBI-736568 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006183 ! DDX24_HUMAN relationship: has_participant CCO:B0058861 ! TMM9B_HUMAN [Term] id: CCO:I0020540 name: ddx24-fadd physical interaction xref: IntAct:EBI-736574 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006183 ! DDX24_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN [Term] id: CCO:I0020541 name: dhx29-tbc1d17 physical interaction xref: IntAct:EBI-736598 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0063506 ! DHX29_HUMAN [Term] id: CCO:I0020542 name: dmpk-gabarap physical interaction xref: IntAct:EBI-736628 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006196 ! GBRAP_HUMAN relationship: has_participant CCO:B0055804 ! DMPK_HUMAN [Term] id: CCO:I0020543 name: dnm1l-sirt3 physical interaction xref: IntAct:EBI-736637 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054320 ! DNM1L_HUMAN relationship: has_participant CCO:B0058924 ! SIRT3_HUMAN [Term] id: CCO:I0020544 name: doc_1r-wars physical interaction xref: IntAct:EBI-736652 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021811 ! SYWC_HUMAN relationship: has_participant CCO:B0030691 ! Q6IAV4_HUMAN [Term] id: CCO:I0020545 name: dpysl5-hspa5 physical interaction xref: IntAct:EBI-736655 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005843 ! GRP78_HUMAN relationship: has_participant CCO:B0058468 ! DPYL5_HUMAN [Term] id: CCO:I0020546 name: dvl3-ly6h physical interaction xref: IntAct:EBI-736658 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058118 ! DVL3_HUMAN relationship: has_participant CCO:B0063507 ! LY6H_HUMAN [Term] id: CCO:I0020547 name: eif4a2-clns1a physical interaction xref: IntAct:EBI-736661 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN relationship: has_participant CCO:B0063508 ! ICLN_HUMAN [Term] id: CCO:I0020548 name: eif4ebp1-mvd physical interaction xref: IntAct:EBI-736664 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0025709 ! ERG19_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN [Term] id: CCO:I0020549 name: eif4g1-anxa5 physical interaction xref: IntAct:EBI-736667 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015822 ! ANXA5_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN [Term] id: CCO:I0020550 name: epb49-snrpd2 physical interaction xref: IntAct:EBI-736673 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018244 ! SMD2_HUMAN relationship: has_participant CCO:B0055791 ! DEMA_HUMAN [Term] id: CCO:I0020551 name: f10-mgst3 physical interaction xref: IntAct:EBI-736688 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054386 ! MGST3_HUMAN relationship: has_participant CCO:B0063456 ! FA10_HUMAN [Term] id: CCO:I0020552 name: fcgr2b-c14orf1 physical interaction xref: IntAct:EBI-736697 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006287 ! ERG28_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN [Term] id: CCO:I0020553 name: fkbp8-mapk14 physical interaction xref: IntAct:EBI-736703 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0055978 ! FKBP8_HUMAN [Term] id: CCO:I0020554 name: kiaa1626-anxa9 physical interaction xref: IntAct:EBI-736718 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015830 ! ANXA9_HUMAN relationship: has_participant CCO:B0058804 ! ARGAL_HUMAN [Term] id: CCO:I0020555 name: kiaa1626-drap1 physical interaction xref: IntAct:EBI-736721 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040686 ! NC2A_HUMAN relationship: has_participant CCO:B0058804 ! ARGAL_HUMAN [Term] id: CCO:I0020556 name: kiaa1626-nr4a1 physical interaction xref: IntAct:EBI-736724 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055150 ! NR4A1_HUMAN relationship: has_participant CCO:B0058804 ! ARGAL_HUMAN [Term] id: CCO:I0020557 name: flj10842-pdlim1 physical interaction xref: IntAct:EBI-736733 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005319 ! PDLI1_HUMAN relationship: has_participant CCO:B0063509 ! Q75KN0_HUMAN [Term] id: CCO:I0020558 name: flj20758-tbpl1 physical interaction xref: IntAct:EBI-736763 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055618 ! TBPL1_HUMAN relationship: has_participant CCO:B0063510 ! PTCD3_HUMAN [Term] id: CCO:I0020559 name: flj38944-eef1g physical interaction xref: IntAct:EBI-736778 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006079 ! EF1G_HUMAN relationship: has_participant CCO:B0058190 ! EID2B_HUMAN [Term] id: CCO:I0020560 name: flt3lg-pfn2 physical interaction xref: IntAct:EBI-736784 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0055435 ! FLT3L_HUMAN [Term] id: CCO:I0020561 name: glra2-bat3 physical interaction xref: IntAct:EBI-736799 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006127 ! BAT3_HUMAN relationship: has_participant CCO:B0022917 ! GLRA2_HUMAN [Term] id: CCO:I0020562 name: glra2-gpr108 physical interaction xref: IntAct:EBI-736802 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0022917 ! GLRA2_HUMAN relationship: has_participant CCO:B0063511 ! Q96I30_HUMAN [Term] id: CCO:I0020563 name: btbd10-acin1 physical interaction xref: IntAct:EBI-736805 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006271 ! BTBDA_HUMAN relationship: has_participant CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:I0020564 name: btbd10-lama5 physical interaction xref: IntAct:EBI-736808 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006271 ! BTBDA_HUMAN relationship: has_participant CCO:B0054418 ! LAMA5_HUMAN [Term] id: CCO:I0020565 name: gnb5-eif3s1 physical interaction xref: IntAct:EBI-736811 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006142 ! GBB5_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN [Term] id: CCO:I0020566 name: gnb5-nr6a1 physical interaction xref: IntAct:EBI-736814 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006142 ! GBB5_HUMAN relationship: has_participant CCO:B0024873 ! NR6A1_HUMAN [Term] id: CCO:I0020567 name: golgb1-cav2 physical interaction xref: IntAct:EBI-736817 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005462 ! CAV2_HUMAN relationship: has_participant CCO:B0006272 ! GOGB1_HUMAN [Term] id: CCO:I0020568 name: golgb1-vti1b physical interaction xref: IntAct:EBI-736826 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006272 ! GOGB1_HUMAN relationship: has_participant CCO:B0059110 ! VTI1B_HUMAN [Term] id: CCO:I0020569 name: golph2-wdr39 physical interaction xref: IntAct:EBI-736838 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006331 ! GOLM1_HUMAN relationship: has_participant CCO:B0054691 ! CIAO1_HUMAN [Term] id: CCO:I0020570 name: herpud1-impa2 physical interaction xref: IntAct:EBI-736889 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0026851 ! HERP1_HUMAN relationship: has_participant CCO:B0042283 ! IMPA2_HUMAN [Term] id: CCO:I0020571 name: hist1h2ac-tfap2b physical interaction xref: IntAct:EBI-736895 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005680 ! AP2B_HUMAN relationship: has_participant CCO:B0021917 ! H2A1C_HUMAN [Term] id: CCO:I0020572 name: hk1-scmh1 physical interaction xref: IntAct:EBI-736898 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018524 ! HXK1_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:I0020573 name: znhit4-rxrip110 physical interaction xref: IntAct:EBI-736901 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058381 ! UIMC1_HUMAN relationship: has_participant CCO:B0061990 ! IN80B_HUMAN [Term] id: CCO:I0020574 name: hnrph3-ccl13 physical interaction xref: IntAct:EBI-736913 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006277 ! HNRH3_HUMAN relationship: has_participant CCO:B0038966 ! CCL13_HUMAN [Term] id: CCO:I0020575 name: hrmt1l2-idh3b physical interaction xref: IntAct:EBI-736922 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0063220 ! IDH3B_HUMAN [Term] id: CCO:I0020576 name: igfbp5-loc56902 physical interaction xref: IntAct:EBI-736943 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006240 ! PNO1_HUMAN relationship: has_participant CCO:B0055174 ! IBP5_HUMAN [Term] id: CCO:I0020577 name: irak4-tbpl1 physical interaction xref: IntAct:EBI-736955 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055618 ! TBPL1_HUMAN relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN [Term] id: CCO:I0020578 name: itgb3bp-os_9 physical interaction xref: IntAct:EBI-736958 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0063512 ! Q6IBL2_HUMAN [Term] id: CCO:I0020579 name: kars-frs3 physical interaction xref: IntAct:EBI-736967 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006279 ! SYK_HUMAN relationship: has_participant CCO:B0054491 ! FRS3_HUMAN [Term] id: CCO:I0020580 name: kctd15-rfp physical interaction xref: IntAct:EBI-736973 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005981 ! TRI27_HUMAN relationship: has_participant CCO:B0063417 ! KCD15_HUMAN [Term] id: CCO:I0020581 name: lama3-slc35e1 physical interaction xref: IntAct:EBI-737021 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0063513 ! S35E1_HUMAN relationship: has_participant CCO:B0063514 ! LAMA3_HUMAN [Term] id: CCO:I0020582 name: litaf-comt physical interaction xref: IntAct:EBI-737030 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058449 ! LITAF_HUMAN relationship: has_participant CCO:B0063160 ! COMT_HUMAN [Term] id: CCO:I0020583 name: litaf-flj10324 physical interaction xref: IntAct:EBI-737033 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0043449 ! Q75LH2_HUMAN relationship: has_participant CCO:B0058449 ! LITAF_HUMAN [Term] id: CCO:I0020584 name: loc124402-med8 physical interaction xref: IntAct:EBI-737039 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0063515 ! F100A_HUMAN [Term] id: CCO:I0020585 name: lrsam1-myl2 physical interaction xref: IntAct:EBI-737078 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006335 ! LRSM1_HUMAN relationship: has_participant CCO:B0054982 ! MLRV_HUMAN [Term] id: CCO:I0020586 name: lrsam1-rxrg physical interaction xref: IntAct:EBI-737081 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006335 ! LRSM1_HUMAN relationship: has_participant CCO:B0024881 ! RXRG_HUMAN [Term] id: CCO:I0020587 name: m6prbp1-tbpl1 physical interaction xref: IntAct:EBI-737090 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055618 ! TBPL1_HUMAN relationship: has_participant CCO:B0063516 ! M6PBP_HUMAN [Term] id: CCO:I0020588 name: map3k12-rpl18a physical interaction xref: IntAct:EBI-737099 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006300 ! RL18A_HUMAN relationship: has_participant CCO:B0018778 ! M3K12_HUMAN [Term] id: CCO:I0020589 name: mark3-asb13 physical interaction xref: IntAct:EBI-737105 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005229 ! MARK3_HUMAN relationship: has_participant CCO:B0058029 ! ASB13_HUMAN [Term] id: CCO:I0020590 name: mark4-hps6 physical interaction xref: IntAct:EBI-737117 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0006286 ! HPS6_HUMAN [Term] id: CCO:I0020591 name: mcm3ap-crmp1 physical interaction xref: IntAct:EBI-737126 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006074 ! DPYL1_HUMAN relationship: has_participant CCO:B0054547 ! MCM3A_HUMAN [Term] id: CCO:I0020592 name: mgc5309-jmjd2b physical interaction xref: IntAct:EBI-737147 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0054713 ! JHD3B_HUMAN [Term] id: CCO:I0020593 name: mgc5309-pbp physical interaction xref: IntAct:EBI-737150 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0027514 ! PEBP1_HUMAN [Term] id: CCO:I0020594 name: mpp3-b3gntl1 physical interaction xref: IntAct:EBI-737165 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063517 ! B3GNL_HUMAN [Term] id: CCO:I0020595 name: mpp3-crabp1 physical interaction xref: IntAct:EBI-737168 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0034076 ! RABP1_HUMAN [Term] id: CCO:I0020596 name: mpp3-idua physical interaction xref: IntAct:EBI-737171 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063518 ! IDUA_HUMAN [Term] id: CCO:I0020597 name: mpp3-insm1 physical interaction xref: IntAct:EBI-737174 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0055685 ! INSM1_HUMAN [Term] id: CCO:I0020598 name: mpp3-kbtbd4 physical interaction xref: IntAct:EBI-737177 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063519 ! KBTB4_HUMAN [Term] id: CCO:I0020599 name: mpp3-mopt physical interaction xref: IntAct:EBI-737180 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063520 ! MORN2_HUMAN [Term] id: CCO:I0020600 name: mpp3-rab31 physical interaction xref: IntAct:EBI-737183 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0063521 ! RAB31_HUMAN [Term] id: CCO:I0020601 name: mpp3-sf3b3 physical interaction xref: IntAct:EBI-737189 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0026181 ! SF3B3_HUMAN [Term] id: CCO:I0020602 name: mpp3-trim41 physical interaction xref: IntAct:EBI-737192 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0062904 ! TRI41_HUMAN [Term] id: CCO:I0020603 name: mrpl12-tmem51 physical interaction xref: IntAct:EBI-737198 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055501 ! RM12_HUMAN relationship: has_participant CCO:B0063522 ! TMM51_HUMAN [Term] id: CCO:I0020604 name: mrpl38-prim1 physical interaction xref: IntAct:EBI-737201 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005507 ! PRI1_HUMAN relationship: has_participant CCO:B0063523 ! RM38_HUMAN [Term] id: CCO:I0020605 name: sept9-rab10 physical interaction xref: IntAct:EBI-737213 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0032549 ! RAB10_HUMAN relationship: has_participant CCO:B0063524 ! Q9HC74_HUMAN [Term] id: CCO:I0020606 name: nap1l1-hba1 physical interaction xref: IntAct:EBI-737222 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0006221 ! HBA_HUMAN [Term] id: CCO:I0020607 name: nipsnap1-tbc1d17 physical interaction xref: IntAct:EBI-737231 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0006298 ! NIPS1_HUMAN [Term] id: CCO:I0020608 name: nol4-hrmt1l2 physical interaction xref: IntAct:EBI-737234 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0062875 ! NOL4_HUMAN [Term] id: CCO:I0020609 name: nova1-smarcc2 physical interaction xref: IntAct:EBI-737237 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0063525 ! NOVA1_HUMAN [Term] id: CCO:I0020610 name: nsfl1c-anp32a physical interaction xref: IntAct:EBI-737240 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006073 ! AN32A_HUMAN relationship: has_participant CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:I0020611 name: nsfl1c-glmn physical interaction xref: IntAct:EBI-737246 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058117 ! GLMN_HUMAN relationship: has_participant CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:I0020612 name: nsfl1c-srp14 physical interaction xref: IntAct:EBI-737249 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055316 ! SRP14_HUMAN relationship: has_participant CCO:B0063526 ! NSF1C_HUMAN [Term] id: CCO:I0020613 name: olfm2-gnb5 physical interaction xref: IntAct:EBI-737261 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006142 ! GBB5_HUMAN relationship: has_participant CCO:B0031787 ! NOE2_HUMAN [Term] id: CCO:I0020614 name: olfm2-robo2 physical interaction xref: IntAct:EBI-737270 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031787 ! NOE2_HUMAN relationship: has_participant CCO:B0058810 ! ROBO2_HUMAN [Term] id: CCO:I0020615 name: olfm2-sui1 physical interaction xref: IntAct:EBI-737276 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0019928 ! EIF1_HUMAN relationship: has_participant CCO:B0031787 ! NOE2_HUMAN [Term] id: CCO:I0020616 name: pak4-p66alpha physical interaction xref: IntAct:EBI-737288 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005907 ! P66A_HUMAN relationship: has_participant CCO:B0054821 ! PAK4_HUMAN [Term] id: CCO:I0020617 name: pank4-pea15 physical interaction xref: IntAct:EBI-737291 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050004 ! PANK4_HUMAN relationship: has_participant CCO:B0056045 ! PEA15_HUMAN [Term] id: CCO:I0020618 name: pcmt1-apoa1 physical interaction xref: IntAct:EBI-737297 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0028600 ! APOA1_HUMAN relationship: has_participant CCO:B0062985 ! PIMT_HUMAN [Term] id: CCO:I0020619 name: pdcd6ip-ramp3 physical interaction xref: IntAct:EBI-737303 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0049915 ! RAMP3_HUMAN relationship: has_participant CCO:B0063149 ! PDC6I_HUMAN [Term] id: CCO:I0020620 name: pdcd8-c4orf14 physical interaction xref: IntAct:EBI-737306 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN relationship: has_participant CCO:B0026813 ! CD014_HUMAN [Term] id: CCO:I0020621 name: pdcd8-kibra physical interaction xref: IntAct:EBI-737309 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006200 ! WWC1_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN [Term] id: CCO:I0020622 name: pdk2-hd physical interaction xref: IntAct:EBI-737315 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0016811 ! PDK2_HUMAN [Term] id: CCO:I0020623 name: pdk2-hic2 physical interaction xref: IntAct:EBI-737318 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0016811 ! PDK2_HUMAN relationship: has_participant CCO:B0023371 ! HIC2_HUMAN [Term] id: CCO:I0020624 name: pdpk1-cdan1 physical interaction xref: IntAct:EBI-737321 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006233 ! PDPK1_HUMAN relationship: has_participant CCO:B0063527 ! CDAN1_HUMAN [Term] id: CCO:I0020625 name: phyhip-nfe2 physical interaction xref: IntAct:EBI-737348 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006241 ! PHYIP_HUMAN relationship: has_participant CCO:B0056162 ! NFE2_HUMAN [Term] id: CCO:I0020626 name: pja1-znf440 physical interaction xref: IntAct:EBI-737363 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006202 ! PJA1_HUMAN relationship: has_participant CCO:B0057388 ! ZN440_HUMAN [Term] id: CCO:I0020627 name: pla2g10-myo10 physical interaction xref: IntAct:EBI-737372 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058826 ! MYO10_HUMAN relationship: has_participant CCO:B0063528 ! PA2GX_HUMAN [Term] id: CCO:I0020628 name: plaur-surf2 physical interaction xref: IntAct:EBI-737378 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0055723 ! UPAR_HUMAN relationship: has_participant CCO:B0063529 ! SURF2_HUMAN [Term] id: CCO:I0020629 name: por-g22p1 physical interaction xref: IntAct:EBI-737402 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0063530 ! NCPR_HUMAN [Term] id: CCO:I0020630 name: ppp1r1b-robo2 physical interaction xref: IntAct:EBI-737420 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058810 ! ROBO2_HUMAN relationship: has_participant CCO:B0059099 ! PPR1B_HUMAN [Term] id: CCO:I0020631 name: pqbp1-cltb physical interaction xref: IntAct:EBI-737423 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN relationship: has_participant CCO:B0063531 ! CLCB_HUMAN [Term] id: CCO:I0020632 name: pqbp1-rab8a physical interaction xref: IntAct:EBI-737426 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN relationship: has_participant CCO:B0032548 ! RAB8A_HUMAN [Term] id: CCO:I0020633 name: prei3-egln2 physical interaction xref: IntAct:EBI-737429 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0029357 ! EGLN2_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0020634 name: prei3-elk1 physical interaction xref: IntAct:EBI-737432 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005637 ! ELK1_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0020635 name: prei3-myo9b physical interaction xref: IntAct:EBI-737438 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031122 ! MYO9B_HUMAN relationship: has_participant CCO:B0031198 ! MOBL3_HUMAN [Term] id: CCO:I0020636 name: ptov1-tmcc2 physical interaction xref: IntAct:EBI-737468 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006294 ! PTOV1_HUMAN relationship: has_participant CCO:B0051710 ! TMCC2_HUMAN [Term] id: CCO:I0020637 name: rab11b-olfm2 physical interaction xref: IntAct:EBI-737474 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0031787 ! NOE2_HUMAN relationship: has_participant CCO:B0038434 ! RB11B_HUMAN [Term] id: CCO:I0020638 name: rab18-tom1l1 physical interaction xref: IntAct:EBI-737477 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006203 ! TM1L1_HUMAN relationship: has_participant CCO:B0058836 ! RAB18_HUMAN [Term] id: CCO:I0020639 name: rab1a-syt5 physical interaction xref: IntAct:EBI-737486 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0040093 ! SYT5_HUMAN [Term] id: CCO:I0020640 name: rab1a-znf593 physical interaction xref: IntAct:EBI-737489 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0054328 ! ZN593_HUMAN [Term] id: CCO:I0020641 name: rab35-flj21945 physical interaction xref: IntAct:EBI-737492 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056054 ! RAB35_HUMAN relationship: has_participant CCO:B0063461 ! CB044_HUMAN [Term] id: CCO:I0020642 name: rab35-gnpat physical interaction xref: IntAct:EBI-737495 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040018 ! GNPAT_HUMAN relationship: has_participant CCO:B0056054 ! RAB35_HUMAN [Term] id: CCO:I0020643 name: rab35-idh3b physical interaction xref: IntAct:EBI-737498 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0056054 ! RAB35_HUMAN relationship: has_participant CCO:B0063220 ! IDH3B_HUMAN [Term] id: CCO:I0020644 name: rab35-ptprs physical interaction xref: IntAct:EBI-737501 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006104 ! PTPRS_HUMAN relationship: has_participant CCO:B0056054 ! RAB35_HUMAN [Term] id: CCO:I0020645 name: rab4a-sod2 physical interaction xref: IntAct:EBI-737507 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006295 ! RAB4A_HUMAN relationship: has_participant CCO:B0033778 ! SODM_HUMAN [Term] id: CCO:I0020646 name: raly-pik3cd physical interaction xref: IntAct:EBI-737513 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018352 ! PK3CD_HUMAN relationship: has_participant CCO:B0021291 ! RALY_HUMAN [Term] id: CCO:I0020647 name: rasa4-c16orf34 physical interaction xref: IntAct:EBI-737522 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054478 ! RASL2_HUMAN relationship: has_participant CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:I0020648 name: rasa4-apmap physical interaction xref: IntAct:EBI-737525 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054478 ! RASL2_HUMAN relationship: has_participant CCO:B0063532 ! APMAP_HUMAN [Term] id: CCO:I0020649 name: rasa4-erbb3 physical interaction xref: IntAct:EBI-737528 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0054478 ! RASL2_HUMAN [Term] id: CCO:I0020650 name: rasa4-ovgp1 physical interaction xref: IntAct:EBI-737531 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0029646 ! OVGP1_HUMAN relationship: has_participant CCO:B0054478 ! RASL2_HUMAN [Term] id: CCO:I0020651 name: recql5-stambp physical interaction xref: IntAct:EBI-737546 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006224 ! RECQ5_HUMAN relationship: has_participant CCO:B0054776 ! STABP_HUMAN [Term] id: CCO:I0020652 name: rit1-ap2a1 physical interaction xref: IntAct:EBI-737564 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006229 ! RIT1_HUMAN relationship: has_participant CCO:B0063354 ! AP2A1_HUMAN [Term] id: CCO:I0020653 name: rit1-ifrd1 physical interaction xref: IntAct:EBI-737567 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006229 ! RIT1_HUMAN relationship: has_participant CCO:B0063533 ! IFRD1_HUMAN [Term] id: CCO:I0020654 name: rnf2-sumo2 physical interaction xref: IntAct:EBI-737579 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0020552 ! RING2_HUMAN relationship: has_participant CCO:B0063001 ! SUMO2_HUMAN [Term] id: CCO:I0020655 name: rpn1-dpf1 physical interaction xref: IntAct:EBI-737603 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040688 ! RPN1_HUMAN relationship: has_participant CCO:B0058092 ! DPF1_HUMAN [Term] id: CCO:I0020656 name: rpn1-sigirr physical interaction xref: IntAct:EBI-737612 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040688 ! RPN1_HUMAN relationship: has_participant CCO:B0056756 ! SIGIR_HUMAN [Term] id: CCO:I0020657 name: rpn1-wsb2 physical interaction xref: IntAct:EBI-737615 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0040688 ! RPN1_HUMAN relationship: has_participant CCO:B0058971 ! WSB2_HUMAN [Term] id: CCO:I0020658 name: rps27-masa physical interaction xref: IntAct:EBI-737618 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0033001 ! RS27_HUMAN relationship: has_participant CCO:B0042028 ! ENOPH_HUMAN [Term] id: CCO:I0020659 name: rras2-pawr physical interaction xref: IntAct:EBI-737624 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN relationship: has_participant CCO:B0058234 ! PAWR_HUMAN [Term] id: CCO:I0020660 name: rxrg-chgb physical interaction xref: IntAct:EBI-737630 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006217 ! SCG1_HUMAN relationship: has_participant CCO:B0024881 ! RXRG_HUMAN [Term] id: CCO:I0020661 name: rxrg-loc56902 physical interaction xref: IntAct:EBI-737633 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006240 ! PNO1_HUMAN relationship: has_participant CCO:B0024881 ! RXRG_HUMAN [Term] id: CCO:I0020662 name: s100a8-rab17 physical interaction xref: IntAct:EBI-737639 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006159 ! S10A8_HUMAN relationship: has_participant CCO:B0058657 ! RAB17_HUMAN [Term] id: CCO:I0020663 name: sh3bp2-tf physical interaction xref: IntAct:EBI-737660 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054876 ! TRFE_HUMAN relationship: has_participant CCO:B0055636 ! 3BP2_HUMAN [Term] id: CCO:I0020664 name: slc1a5-tbc1d17 physical interaction xref: IntAct:EBI-737669 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0063082 ! AAAT_HUMAN [Term] id: CCO:I0020665 name: slc25a20-c16orf34 physical interaction xref: IntAct:EBI-737672 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0054520 ! MCAT_HUMAN relationship: has_participant CCO:B0063499 ! HN1L_HUMAN [Term] id: CCO:I0020666 name: sncaip-aes physical interaction xref: IntAct:EBI-737681 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005987 ! AES_HUMAN relationship: has_participant CCO:B0006235 ! SNCAP_HUMAN [Term] id: CCO:I0020667 name: sncaip-agxt physical interaction xref: IntAct:EBI-737684 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006235 ! SNCAP_HUMAN relationship: has_participant CCO:B0063534 ! SPYA_HUMAN [Term] id: CCO:I0020668 name: snta1-med8 physical interaction xref: IntAct:EBI-737690 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0063265 ! SNTA1_HUMAN [Term] id: CCO:I0020669 name: snx24-sh3gl3 physical interaction xref: IntAct:EBI-737693 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0063535 ! SNX24_HUMAN [Term] id: CCO:I0020670 name: ssrp1-robo2 physical interaction xref: IntAct:EBI-737705 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN relationship: has_participant CCO:B0058810 ! ROBO2_HUMAN [Term] id: CCO:I0020671 name: strn4-dffa physical interaction xref: IntAct:EBI-737708 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0054307 ! DFFA_HUMAN [Term] id: CCO:I0020672 name: strn4-flj23342 physical interaction xref: IntAct:EBI-737717 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063536 ! CK061_HUMAN [Term] id: CCO:I0020673 name: strn4-cxorf26 physical interaction xref: IntAct:EBI-737720 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0063537 ! CX026_HUMAN [Term] id: CCO:I0020674 name: strn4-mif physical interaction xref: IntAct:EBI-737723 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0055021 ! MIF_HUMAN [Term] id: CCO:I0020675 name: strn4-wnt7a physical interaction xref: IntAct:EBI-737729 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0054341 ! WNT7A_HUMAN [Term] id: CCO:I0020676 name: supt4h1-anxa5 physical interaction xref: IntAct:EBI-737738 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015822 ! ANXA5_HUMAN relationship: has_participant CCO:B0051010 ! SPT4H_HUMAN [Term] id: CCO:I0020677 name: th1l-aamp physical interaction xref: IntAct:EBI-737759 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0050226 ! AAMP_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN [Term] id: CCO:I0020678 name: tmem22-centb5 physical interaction xref: IntAct:EBI-737771 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0058318 ! CENB5_HUMAN relationship: has_participant CCO:B0063538 ! TMM22_HUMAN [Term] id: CCO:I0020679 name: tnpo2-pik3cd physical interaction xref: IntAct:EBI-737780 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0018352 ! PK3CD_HUMAN relationship: has_participant CCO:B0024778 ! TNPO2_HUMAN [Term] id: CCO:I0020680 name: tpi1-ccl11 physical interaction xref: IntAct:EBI-737804 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0015866 ! TPIS_HUMAN relationship: has_participant CCO:B0038969 ! CCL11_HUMAN [Term] id: CCO:I0020681 name: trim16-setdb1 physical interaction xref: IntAct:EBI-737810 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0063539 ! TRI16_HUMAN [Term] id: CCO:I0020682 name: ubtf-chgb physical interaction xref: IntAct:EBI-737828 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006217 ! SCG1_HUMAN relationship: has_participant CCO:B0055088 ! UBF1_HUMAN [Term] id: CCO:I0020683 name: ulk2-eef1b2 physical interaction xref: IntAct:EBI-737831 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005752 ! EF1B_HUMAN relationship: has_participant CCO:B0006252 ! ULK2_HUMAN [Term] id: CCO:I0020684 name: usp11-tbl3 physical interaction xref: IntAct:EBI-737840 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0006309 ! TBL3_HUMAN relationship: has_participant CCO:B0063143 ! UBP11_HUMAN [Term] id: CCO:I0020685 name: vps11-tfap2b physical interaction xref: IntAct:EBI-737846 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0005680 ! AP2B_HUMAN relationship: has_participant CCO:B0063398 ! VPS11_HUMAN [Term] id: CCO:I0020686 name: vps28-fabp3 physical interaction xref: IntAct:EBI-737852 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0034070 ! FABPH_HUMAN relationship: has_participant CCO:B0062968 ! VPS28_HUMAN [Term] id: CCO:I0020687 name: wdr3-pde10a physical interaction xref: IntAct:EBI-737861 is_a: CCO:Y0000060 ! physical association relationship: has_participant CCO:B0059289 ! PDE10_HUMAN relationship: has_participant CCO:B0063540 ! WDR3_HUMAN [Term] id: CCO:P0000001 name: mitotic spindle elongation namespace: biological_process def: "Lengthening of the distance between poles of the mitotic spindle." [GOC:mah] synonym: "spindle elongation during mitosis" EXACT [] xref: GO:0000022 is_a: CCO:P0000293 ! spindle elongation relationship: has_participant CCO:B0001394 ! PRC1_HUMAN relationship: has_participant CCO:B0001716 ! KIF23_HUMAN relationship: part_of CCO:P0000068 ! mitotic spindle organization and biogenesis [Term] id: CCO:P0000002 name: mitotic sister chromatid segregation namespace: biological_process def: "The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai] synonym: "mitotic chromosome segregation" EXACT [] synonym: "mitotic sister-chromatid adhesion release" NARROW [] xref: GO:0000070 xref: GO:0016359 is_a: CCO:P0000054 ! sister chromatid segregation relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001396 ! BUB3_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001787 ! ESPL1_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0002037 ! DDX11_HUMAN relationship: has_participant CCO:B0002105 ! KIFC1_HUMAN relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: has_participant CCO:B0002168 ! SMC4_HUMAN relationship: has_participant CCO:B0002208 ! KIF25_HUMAN relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000003 name: M phase specific microtubule process namespace: biological_process def: "A microtubule-based process that occurs only during M phase of the cell cycle." [GOC:mah] synonym: "M-phase specific microtubule process" EXACT [] xref: GO:0000072 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: part_of CCO:P0000039 ! M phase [Term] id: CCO:P0000004 name: spindle pole body separation namespace: biological_process def: "A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble." [GOC:sgd_curators] synonym: "spindle pole body separation (sensu Fungi)" EXACT [] synonym: "spindle pole body separation (sensu Saccharomyces)" NARROW [] xref: GO:0000073 xref: GO:0030475 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000302 ! spindle pole body organization and biogenesis [Term] id: CCO:P0000006 name: cell cycle checkpoint namespace: biological_process def: "A point in the eukaryotic cell cycle where progress through the cycle can be halted until conditions are suitable for the cell to proceed to the next stage." [GOC:mah, ISBN:0815316194] xref: GO:0000075 xref: Reactome:212094 xref: Reactome:221853 xref: Reactome:230421 xref: Reactome:238463 xref: Reactome:245004 xref: Reactome:249905 xref: Reactome:252621 xref: Reactome:255806 xref: Reactome:259199 xref: Reactome:262557 xref: Reactome:265381 xref: Reactome:268515 xref: Reactome:274237 xref: Reactome:280705 xref: Reactome:282912 xref: Reactome:286730 xref: Reactome:69620 is_a: CCO:P0000346 ! regulation of cell cycle relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0001413 ! RAD1_HUMAN relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001714 ! XPC_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001821 ! CCNG2_HUMAN relationship: has_participant CCO:B0002077 ! RAD9A_HUMAN relationship: has_participant CCO:B0002084 ! RBBP8_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0005584 ! DDB1_HUMAN relationship: has_participant CCO:B0026248 ! ERCC2_HUMAN relationship: has_participant CCO:B0028502 ! ERCC3_HUMAN [Term] id: CCO:P0000007 name: DNA replication checkpoint namespace: biological_process def: "A signal transduction based surveillance mechanism that prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome." [GOC:rn, PMID:11728327, PMID:12537518] xref: GO:0000076 is_a: CCO:P0000183 ! DNA integrity checkpoint is_a: CCO:P0001581 ! negative regulation of DNA replication initiation relationship: has_participant CCO:B0001426 ! CC45L_HUMAN relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0002077 ! RAD9A_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN [Term] id: CCO:P0000008 name: DNA damage checkpoint namespace: biological_process def: "A signal transduction pathway, induced by DNA damage, that blocks cell cycle progression (in G1, G2 or metaphase) or slows the rate at which S phase proceeds." [PMID:11891124] synonym: "DNA damage response, signal transduction resulting in cell cycle arrest" NARROW [] xref: GO:0000077 is_a: CCO:P0000183 ! DNA integrity checkpoint is_a: CCO:P0002125 ! DNA damage response, signal transduction relationship: has_participant CCO:B0001347 ! FOXN3_HUMAN relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001413 ! RAD1_HUMAN relationship: has_participant CCO:B0001419 ! HUS1_HUMAN relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0001756 ! ATR_HUMAN relationship: has_participant CCO:B0002009 ! ATRIP_HUMAN relationship: has_participant CCO:B0002077 ! RAD9A_HUMAN relationship: has_participant CCO:B0002107 ! FANCJ_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN [Term] id: CCO:P0000009 name: cell morphogenesis checkpoint namespace: biological_process def: "A cell cycle checkpoint observed when aspects of polarity control are defective, which maintains coordination between the process of cellular morphogenesis and the nuclear events of the cell cycle. For example, in budding yeast cell-cycle delay or arrest is induced when aspects of bud formation are defective." [GOC:vw, PMID:14644188] xref: GO:0000078 is_a: CCO:P0000104 ! mitotic cell cycle checkpoint [Term] id: CCO:P0000010 name: regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of CDK activity." [GOC:go_curators] synonym: "regulation of CDK activity" EXACT [] xref: GO:0000079 is_a: CCO:P0000346 ! regulation of cell cycle relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001410 ! CCNT1_HUMAN relationship: has_participant CCO:B0001412 ! CCNT2_HUMAN relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0001453 ! DIRA3_HUMAN relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001552 ! GA45A_HUMAN relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0001585 ! TF2H1_HUMAN relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0001656 ! CCNG1_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001751 ! CD5R2_HUMAN relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN relationship: has_participant CCO:B0001819 ! CDC37_HUMAN relationship: has_participant CCO:B0001823 ! CDKN3_HUMAN relationship: has_participant CCO:B0002044 ! CK5P3_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002116 ! NOG1_HUMAN relationship: has_participant CCO:B0002137 ! RGC32_HUMAN relationship: has_participant CCO:B0002187 ! BCCIP_HUMAN relationship: has_participant CCO:B0002202 ! SRTD1_HUMAN relationship: has_participant CCO:B0002206 ! HERC5_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:P0000011 name: G1 phase of mitotic cell cycle namespace: biological_process def: "Progression through G1 phase, one of two 'gap' phases in the mitotic cell cycle; G1 is the interval between the completion of mitosis and the beginning of DNA synthesis." [ISBN:0815316194] xref: GO:0000080 xref: Reactome:212033 xref: Reactome:221797 xref: Reactome:230372 xref: Reactome:238411 xref: Reactome:69236 is_a: CCO:P0000313 ! G1 phase relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001706 ! FOXO4_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0001815 ! Q16164_HUMAN relationship: has_participant CCO:B0001820 ! M3K11_HUMAN relationship: has_participant CCO:B0002030 ! TBRG4_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: part_of CCO:P0000324 ! interphase of mitotic cell cycle [Term] id: CCO:P0000012 name: G1/S transition of mitotic cell cycle namespace: biological_process def: "Progression from G1 phase to S phase of the mitotic cell cycle." [GOC:mah] xref: GO:0000082 xref: Reactome:212021 xref: Reactome:221784 xref: Reactome:230362 xref: Reactome:238403 xref: Reactome:244953 xref: Reactome:249850 xref: Reactome:252607 xref: Reactome:255745 xref: Reactome:259140 xref: Reactome:262495 xref: Reactome:265325 xref: Reactome:268498 xref: Reactome:274174 xref: Reactome:280647 xref: Reactome:282899 xref: Reactome:286666 xref: Reactome:288375 xref: Reactome:289876 xref: Reactome:290408 xref: Reactome:291794 xref: Reactome:293774 xref: Reactome:69206 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001353 ! PPP6_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001520 ! ERF3A_HUMAN relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001628 ! UB2R1_HUMAN relationship: has_participant CCO:B0001671 ! BCAT1_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0001760 ! CUL2_HUMAN relationship: has_participant CCO:B0001761 ! CUL3_HUMAN relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001823 ! CDKN3_HUMAN relationship: has_participant CCO:B0001862 ! SPDYA_HUMAN relationship: has_participant CCO:B0002027 ! CUL5_HUMAN relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0002194 ! DBF4A_HUMAN relationship: has_participant CCO:B0002236 ! GP132_HUMAN relationship: part_of CCO:P0000324 ! interphase of mitotic cell cycle [Term] id: CCO:P0000013 name: G1/S-specific transcription in mitotic cell cycle namespace: biological_process def: "Any process that regulates transcription such that the target genes are transcribed during the G1/S phase of the mitotic cell cycle." [GOC:mah] xref: GO:0000083 xref: Reactome:69205 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0001817 ! E2F4_HUMAN relationship: has_participant CCO:B0002083 ! GFI1_HUMAN relationship: part_of CCO:P0000012 ! G1/S transition of mitotic cell cycle [Term] id: CCO:P0000014 name: S phase of mitotic cell cycle namespace: biological_process def: "Progression through S phase, the part of the mitotic cell cycle during which DNA synthesis takes place." [ISBN:0815316194] xref: GO:0000084 is_a: CCO:P0000315 ! S phase relationship: has_participant CCO:B0001355 ! CDKA1_HUMAN relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0001776 ! TFDP1_HUMAN relationship: has_participant CCO:B0002037 ! DDX11_HUMAN relationship: part_of CCO:P0000324 ! interphase of mitotic cell cycle [Term] id: CCO:P0000015 name: G2 phase of mitotic cell cycle namespace: biological_process def: "Progression through G2 phase, one of two 'gap' phases in the mitotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of mitosis." [ISBN:0815316194] xref: GO:0000085 xref: Reactome:211891 xref: Reactome:221655 xref: Reactome:230246 xref: Reactome:238281 xref: Reactome:244852 xref: Reactome:249746 xref: Reactome:268392 xref: Reactome:274099 xref: Reactome:280573 xref: Reactome:68911 is_a: CCO:P0000314 ! G2 phase relationship: has_participant CCO:B0001347 ! FOXN3_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0002180 ! GTSE1_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: part_of CCO:P0000324 ! interphase of mitotic cell cycle [Term] id: CCO:P0000016 name: G2/M transition of mitotic cell cycle namespace: biological_process def: "Progression from G2 phase to M phase of the mitotic cell cycle." [GOC:mah] xref: GO:0000086 xref: Reactome:211972 xref: Reactome:221737 xref: Reactome:230316 xref: Reactome:238398 xref: Reactome:244912 xref: Reactome:249804 xref: Reactome:252543 xref: Reactome:255721 xref: Reactome:259114 xref: Reactome:262473 xref: Reactome:265322 xref: Reactome:268466 xref: Reactome:274171 xref: Reactome:280644 xref: Reactome:282855 xref: Reactome:286663 xref: Reactome:69275 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0001825 ! TPD53_HUMAN relationship: has_participant CCO:B0002037 ! DDX11_HUMAN relationship: has_participant CCO:B0002214 ! APC5_HUMAN relationship: has_participant CCO:B0002215 ! APC4_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0002265 ! USH1C_HUMAN relationship: part_of CCO:P0000324 ! interphase of mitotic cell cycle [Term] id: CCO:P0000017 name: M phase of mitotic cell cycle namespace: biological_process def: "Progression through M phase, the part of the mitotic cell cycle during which mitosis takes place." [GOC:mah, ISBN:0815316194] synonym: "M-phase of mitotic cell cycle" EXACT [] xref: GO:0000087 xref: Reactome:212043 xref: Reactome:221806 xref: Reactome:230379 xref: Reactome:238418 xref: Reactome:244995 xref: Reactome:249877 xref: Reactome:252596 xref: Reactome:255795 xref: Reactome:259176 xref: Reactome:262532 xref: Reactome:265359 xref: Reactome:268488 xref: Reactome:282892 xref: Reactome:286702 xref: Reactome:68886 is_a: CCO:P0000039 ! M phase relationship: has_participant CCO:B0001393 ! O43550_HUMAN relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0001577 ! MPIP2_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001807 ! DLGP5_HUMAN relationship: has_participant CCO:B0002056 ! MPPH1_HUMAN relationship: has_participant CCO:B0002071 ! MPH6_HUMAN relationship: has_participant CCO:B0002127 ! Q9H2F0_HUMAN relationship: part_of CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000018 name: mitotic prophase namespace: biological_process def: "Progression through prophase, the initial stage of mitosis in which the chromosomes are condensed but are not yet attached to a mitotic spindle." [ISBN:0815316194] xref: GO:0000088 xref: Reactome:211977 xref: Reactome:221742 xref: Reactome:230322 xref: Reactome:238359 xref: Reactome:244917 xref: Reactome:249807 xref: Reactome:252546 xref: Reactome:255723 xref: Reactome:259116 xref: Reactome:262475 xref: Reactome:268434 xref: Reactome:286639 xref: Reactome:68875 is_a: CCO:P0000319 ! prophase relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000019 name: mitotic metaphase namespace: biological_process def: "Progression through metaphase, the stage of mitosis at which chromosomes are firmly attached to the mitotic spindle at its equator but have not yet segregated to opposite poles." [ISBN:0815316194] xref: GO:0000089 xref: Reactome:68879 is_a: CCO:P0000318 ! metaphase relationship: has_participant CCO:B0001351 ! PESC_HUMAN relationship: has_participant CCO:B0001715 ! CENPE_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000020 name: mitotic anaphase namespace: biological_process def: "Progression through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other." [ISBN:0815316194] xref: GO:0000090 xref: Reactome:68882 is_a: CCO:P0000317 ! anaphase relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN relationship: has_participant CCO:B0002214 ! APC5_HUMAN relationship: has_participant CCO:B0002215 ! APC4_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000021 name: mitotic anaphase A namespace: biological_process def: "Progression through anaphase A, the part of mitotic anaphase in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles." [ISBN:0815316194] xref: GO:0000091 is_a: CCO:P0000020 ! mitotic anaphase [Term] id: CCO:P0000022 name: mitotic anaphase B namespace: biological_process def: "Progression through anaphase B, the part of mitotic anaphase in which the polar microtubules elongate and the two poles of the spindle move farther apart." [ISBN:0815316194] xref: GO:0000092 is_a: CCO:P0000020 ! mitotic anaphase [Term] id: CCO:P0000023 name: mitotic telophase namespace: biological_process def: "Progression through telophase, the last of the stages of mitosis; in the canonical cell cycle, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0000093 is_a: CCO:P0000321 ! telophase relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000024 name: G1-specific transcription in mitotic cell cycle namespace: biological_process def: "Any process that regulates transcription such that the target genes are transcribed during the G1 phase of the mitotic cell cycle." [GOC:mah] xref: GO:0000114 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: part_of CCO:P0000011 ! G1 phase of mitotic cell cycle [Term] id: CCO:P0000025 name: S-phase-specific transcription in mitotic cell cycle namespace: biological_process def: "A cell cycle process that regulates transcription such that the target genes are transcribed during the S phase of the mitotic cell cycle." [GOC:mah] synonym: "S-specific transcription in mitotic cell cycle" EXACT [] xref: GO:0000115 xref: Reactome:69241 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: part_of CCO:P0000014 ! S phase of mitotic cell cycle [Term] id: CCO:P0000026 name: G2-specific transcription in mitotic cell cycle namespace: biological_process def: "Any process that regulates transcription such that the target genes are transcribed during the G2 phase of the mitotic cell cycle." [GOC:mah] xref: GO:0000116 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: part_of CCO:P0000015 ! G2 phase of mitotic cell cycle [Term] id: CCO:P0000027 name: G2/M-specific transcription in mitotic cell cycle namespace: biological_process def: "Any process that regulates transcription such that the target genes are transcribed during the G2/M phase of the mitotic cell cycle." [GOC:mah] xref: GO:0000117 xref: Reactome:69274 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: part_of CCO:P0000016 ! G2/M transition of mitotic cell cycle [Term] id: CCO:P0000028 name: establishment of mitotic spindle orientation namespace: biological_process def: "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures." [GOC:ems] synonym: "establishment of spindle orientation during mitosis" EXACT [] synonym: "mitotic spindle orientation" EXACT [] synonym: "mitotic spindle orientation (sensu Fungi)" NARROW [] synonym: "mitotic spindle orientation (sensu Saccharomyces)" NARROW [] synonym: "orienting of mitotic spindle" EXACT [] xref: GO:0000132 xref: GO:0030607 xref: GO:0030609 is_a: CCO:P0000225 ! establishment of mitotic spindle localization relationship: has_participant CCO:B0001618 ! LIS1_HUMAN [Term] id: CCO:P0000029 name: septin checkpoint namespace: biological_process def: "A cell cycle checkpoint that detects septin defects and responds by inhibiting the mitotic CDK. In Saccharomyces cerevisiae, correct formation of a functional septin cytoskeleton permits the cell to switch to isotropic bud growth and the onset of mitotic chromosome segregation. In the presence of septin defects, the mitotic CDK is inhibited and both the switch to isotropic bud growth and the onset of mitotic chromosome segregation is delayed." [PMID:9925642] xref: GO:0000135 is_a: CCO:P0000178 ! cytokinesis checkpoint [Term] id: CCO:P0000030 name: meiotic spindle organization and biogenesis namespace: biological_process def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle." [GOC:mah] synonym: "meiotic spindle organisation and biogenesis" EXACT [] synonym: "spindle organization and biogenesis during meiosis" EXACT [] xref: GO:0000212 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000385 ! spindle organization and biogenesis relationship: has_participant CCO:B0001548 ! TBG1_HUMAN relationship: part_of CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000031 name: M/G1 transition of mitotic cell cycle namespace: biological_process def: "Progression from M phase to G1 phase of the mitotic cell cycle." [GOC:mah] xref: GO:0000216 xref: Reactome:211997 xref: Reactome:221761 xref: Reactome:230342 xref: Reactome:238378 xref: Reactome:244933 xref: Reactome:249898 xref: Reactome:252623 xref: Reactome:255800 xref: Reactome:259165 xref: Reactome:262551 xref: Reactome:265375 xref: Reactome:274161 xref: Reactome:280634 xref: Reactome:286652 xref: Reactome:68874 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000324 ! interphase of mitotic cell cycle [Term] id: CCO:P0000032 name: mitotic prometaphase namespace: biological_process def: "Progression through prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles." [GOC:mah, ISBN:0198547684] xref: GO:0000236 xref: Reactome:68877 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000033 name: leptotene namespace: biological_process def: "Progression through the first stage of prophase I in meiosis, in which chromosomes first become visible." [ISBN:0198547684] xref: GO:0000237 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000119 ! meiotic prophase I [Term] id: CCO:P0000034 name: zygotene namespace: biological_process def: "Progression through the second stage of prophase I in meiosis, in which each chromosome pairs with its homolog; the two become aligned and crossing over may occur." [ISBN:0198547684] xref: GO:0000238 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000119 ! meiotic prophase I [Term] id: CCO:P0000035 name: pachytene namespace: biological_process def: "Progression through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." [ISBN:0198547684] xref: GO:0000239 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001358 ! OVOL1_HUMAN relationship: part_of CCO:P0000119 ! meiotic prophase I [Term] id: CCO:P0000036 name: diplotene namespace: biological_process def: "Progression through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." [ISBN:0198547684] xref: GO:0000240 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000119 ! meiotic prophase I [Term] id: CCO:P0000037 name: diakinesis namespace: biological_process def: "Progression through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." [ISBN:0198547684] xref: GO:0000241 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000119 ! meiotic prophase I [Term] id: CCO:P0000038 name: mitotic cell cycle namespace: biological_process def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278] xref: GO:0000278 xref: Reactome:212083 xref: Reactome:221841 xref: Reactome:230408 xref: Reactome:238450 xref: Reactome:244991 xref: Reactome:249871 xref: Reactome:252608 xref: Reactome:255794 xref: Reactome:259188 xref: Reactome:262544 xref: Reactome:265374 xref: Reactome:268486 xref: Reactome:274210 xref: Reactome:280680 xref: Reactome:282900 xref: Reactome:286715 xref: Reactome:288392 xref: Reactome:289890 xref: Reactome:290421 xref: Reactome:291802 xref: Reactome:293782 xref: Reactome:69278 is_a: CCO:P0000066 ! cell cycle relationship: has_participant CCO:B0001577 ! MPIP2_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001797 ! CND2_HUMAN relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0002099 ! CP250_HUMAN relationship: has_participant CCO:B0002179 ! PLK2_HUMAN [Term] id: CCO:P0000039 name: M phase namespace: biological_process def: "Progression through M phase, the part of the cell cycle comprising nuclear division." [ISBN:0815316194] synonym: "M-phase" EXACT [] xref: GO:0000279 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0002068 ! Q99539_HUMAN relationship: has_participant CCO:B0002069 ! Q99540_HUMAN [Term] id: CCO:P0000040 name: cytokinesis after mitosis namespace: biological_process def: "A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." [GOC:ai] xref: GO:0000281 is_a: CCO:P0000212 ! cytokinesis during cell cycle relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN [Term] id: CCO:P0000041 name: re-entry into mitotic cell cycle namespace: biological_process def: "The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state." [GOC:krc] xref: GO:0000320 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001551 ! CCND1_HUMAN [Term] id: CCO:P0000042 name: re-entry into mitotic cell cycle after pheromone arrest namespace: biological_process def: "The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated." [GOC:krc, PMID:9927449] synonym: "re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)" NARROW [] xref: GO:0000321 is_a: CCO:P0000041 ! re-entry into mitotic cell cycle is_a: CCO:P0000446 ! adaptation to pheromone during conjugation with cellular fusion [Term] id: CCO:P0000043 name: achiasmate meiosis I namespace: biological_process def: "The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata." [GOC:elh, GOC:sart, PMID:10690419] xref: GO:0000705 is_a: CCO:P0000118 ! meiosis I relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN [Term] id: CCO:P0000044 name: meiotic DNA double-strand break processing namespace: biological_process def: "The cell cycle process whereby the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis." [GOC:elh, PMID:9334324] xref: GO:0000706 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000063 ! meiotic gene conversion relationship: part_of CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000045 name: meiotic DNA recombinase assembly namespace: biological_process def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA." [GOC:elh, PMID:11459983] xref: GO:0000707 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000063 ! meiotic gene conversion relationship: part_of CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000046 name: meiotic strand invasion namespace: biological_process def: "The cell cycle process whereby the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis." [GOC:elh, PMID:10915877] synonym: "meiotic D-loop biosynthesis" RELATED [] synonym: "meiotic D-loop formation" RELATED [] xref: GO:0000708 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000063 ! meiotic gene conversion relationship: part_of CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000047 name: meiotic joint molecule formation namespace: biological_process def: "The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA." [GOC:elh, PMID:8521495] xref: GO:0000709 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000048 name: meiotic mismatch repair namespace: biological_process def: "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis." [GOC:elh, PMID:10357855] xref: GO:0000710 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000645 ! mismatch repair relationship: part_of CCO:P0000063 ! meiotic gene conversion relationship: part_of CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000049 name: meiotic DNA repair synthesis namespace: biological_process def: "During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template." [GOC:elh, PMID:9334324] xref: GO:0000711 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000442 ! DNA synthesis during DNA repair relationship: part_of CCO:P0000063 ! meiotic gene conversion relationship: part_of CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000050 name: resolution of meiotic joint molecules as recombinants namespace: biological_process def: "The cleavage and rejoining of Holliday junctions formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged." [GOC:elh, PMID:11733053] synonym: "crossover biosynthesis" NARROW [] synonym: "crossover formation" NARROW [] synonym: "formation of chiasmata" NARROW [] synonym: "homologous chromosome separation at meiosis I" EXACT [] synonym: "meiotic homologous chromosome separation" RELATED [] xref: GO:0000712 is_a: CCO:P0000305 ! meiotic chromosome separation relationship: part_of CCO:P0000122 ! meiotic recombination relationship: part_of CCO:P0000239 ! homologous chromosome segregation [Term] id: CCO:P0000051 name: meiotic heteroduplex formation namespace: biological_process def: "During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules." [GOC:elh, PMID:9334324] xref: GO:0000713 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0001268 ! heteroduplex formation relationship: part_of CCO:P0000063 ! meiotic gene conversion [Term] id: CCO:P0000052 name: meiotic strand displacement namespace: biological_process def: "The cell cycle process whereby the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis." [GOC:elh, PMID:10357855] xref: GO:0000714 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000063 ! meiotic gene conversion [Term] id: CCO:P0000053 name: cell cycle arrest in response to pheromone namespace: biological_process def: "The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a pheromone stimulus." [GOC:clt, GOC:dph, GOC:tb] synonym: "cell cycle arrest (sensu Saccharomyces)" RELATED [] xref: GO:0000751 xref: GO:0030571 is_a: CCO:P0000067 ! cell cycle arrest [Term] id: CCO:P0000054 name: sister chromatid segregation namespace: biological_process def: "The process by which sister chromatids are organized and then physically separated and apportioned to two or more sets." [GOC:ai, GOC:elh] xref: GO:0000819 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: part_of CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0000055 name: cytokinesis by cell plate formation namespace: biological_process def: "The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells." [GOC:clt] synonym: "cytokinesis (sensu Viridiplantae)" NARROW [] xref: GO:0000911 is_a: CCO:P0000212 ! cytokinesis during cell cycle [Term] id: CCO:P0000056 name: formation of actomyosin apparatus involved in cytokinesis namespace: biological_process def: "The formation of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis." [GOC:clt] synonym: "cytokinesis, formation of actomyosin apparatus" EXACT [GOC:dph, GOC:tb] xref: GO:0000912 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000212 ! cytokinesis during cell cycle [Term] id: CCO:P0000057 name: preprophase band formation namespace: biological_process def: "The process of marking the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation." [GOC:clt] xref: GO:0000913 is_a: CCO:P0000696 ! cytokinesis, site selection relationship: part_of CCO:P0000055 ! cytokinesis by cell plate formation [Term] id: CCO:P0000058 name: phragmoplast formation namespace: biological_process def: "The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles)." [GOC:clt] xref: GO:0000914 is_a: CCO:P0000056 ! formation of actomyosin apparatus involved in cytokinesis relationship: part_of CCO:P0000055 ! cytokinesis by cell plate formation [Term] id: CCO:P0000059 name: cytokinesis, contractile ring formation namespace: biological_process def: "The process of formation of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis." [GOC:clt] synonym: "constriction ring assembly" NARROW [] synonym: "cytokinesis, actomyosin ring biosynthesis" EXACT [] synonym: "cytokinesis, actomyosin ring formation" EXACT [] synonym: "cytokinesis, contractile ring assembly" NARROW [] xref: GO:0000915 xref: GO:0045573 is_a: CCO:P0000056 ! formation of actomyosin apparatus involved in cytokinesis relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN [Term] id: CCO:P0000060 name: contractile ring contraction involved in cytokinesis namespace: biological_process def: "The process of an actomyosin ring, which functions in cytokinesis, getting smaller in diameter." [GOC:clt, GOC:dph, GOC:tb] synonym: "cytokinesis, actomyosin ring contraction" EXACT [] synonym: "cytokinesis, contractile ring contraction" EXACT [GOC:dph, GOC:tb] xref: GO:0000916 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000212 ! cytokinesis during cell cycle [Term] id: CCO:P0000061 name: cell plate formation namespace: biological_process def: "The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast." [GOC:clt] xref: GO:0000919 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000055 ! cytokinesis by cell plate formation [Term] id: CCO:P0000062 name: negative regulation of exit from mitosis namespace: biological_process def: "Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:rn] synonym: "down regulation of exit from mitosis" EXACT [] synonym: "down-regulation of exit from mitosis" EXACT [] synonym: "downregulation of exit from mitosis" EXACT [] synonym: "inhibition of exit from mitosis" NARROW [] xref: GO:0001100 is_a: CCO:P0000107 ! regulation of exit from mitosis is_a: CCO:P0000250 ! negative regulation of mitosis relationship: negatively_regulates CCO:P0000152 ! exit from mitosis [Term] id: CCO:P0000063 name: meiotic gene conversion namespace: biological_process def: "The cell cycle process whereby genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele." [ISBN:0815316194] synonym: "gene conversion without reciprocal crossover" EXACT [] xref: GO:0006311 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000064 name: S-phase-specific histone modification namespace: biological_process def: "The covalent alteration of one or more amino acid residues within a histone protein that takes place during, and results in a modification pattern characteristic of, S phase of the cell cycle." [GOC:mah, PMID:9990026] xref: GO:0006324 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000315 ! S phase [Term] id: CCO:P0000065 name: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest namespace: biological_process def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle." [GOC:go_curators] xref: GO:0006977 is_a: CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator relationship: has_participant CCO:B0001398 ! TRIA1_HUMAN relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0002064 ! GML_HUMAN relationship: has_participant CCO:B0002121 ! Q9GZT1_HUMAN relationship: has_participant CCO:B0002180 ! GTSE1_HUMAN relationship: has_participant CCO:B0017902 ! RBM38_HUMAN relationship: part_of CCO:P0000184 ! G1 DNA damage checkpoint [Term] id: CCO:P0000066 name: cell cycle namespace: biological_process def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "cell-division cycle" EXACT [] xref: GO:0007049 is_a: CCO:P0000887 ! cellular process relationship: has_participant CCO:B0001317 ! E2F8_HUMAN relationship: has_participant CCO:B0001318 ! A4D1Y2_HUMAN relationship: has_participant CCO:B0001319 ! A6NC65_HUMAN relationship: has_participant CCO:B0001324 ! A6NFQ9_HUMAN relationship: has_participant CCO:B0001328 ! A6NHZ8_HUMAN relationship: has_participant CCO:B0001334 ! SAC31_HUMAN relationship: has_participant CCO:B0001335 ! A6NKP6_HUMAN relationship: has_participant CCO:B0001339 ! A6NMH6_HUMAN relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001347 ! FOXN3_HUMAN relationship: has_participant CCO:B0001349 ! BIN1_HUMAN relationship: has_participant CCO:B0001350 ! LHR2A_HUMAN relationship: has_participant CCO:B0001352 ! E2F3_HUMAN relationship: has_participant CCO:B0001353 ! PPP6_HUMAN relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001355 ! CDKA1_HUMAN relationship: has_participant CCO:B0001356 ! CTRO_HUMAN relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0001364 ! GAK_HUMAN relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0001369 ! MK13_HUMAN relationship: has_participant CCO:B0001372 ! PPM1D_HUMAN relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001382 ! SEPT4_HUMAN relationship: has_participant CCO:B0001383 ! KLK10_HUMAN relationship: has_participant CCO:B0001384 ! SIAH2_HUMAN relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0001386 ! LEU2_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0001394 ! PRC1_HUMAN relationship: has_participant CCO:B0001395 ! BUB1_HUMAN relationship: has_participant CCO:B0001401 ! GAS2_HUMAN relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0001408 ! EVI5_HUMAN relationship: has_participant CCO:B0001409 ! DBC1_HUMAN relationship: has_participant CCO:B0001410 ! CCNT1_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001412 ! CCNT2_HUMAN relationship: has_participant CCO:B0001416 ! TRI13_HUMAN relationship: has_participant CCO:B0001420 ! PFD1_HUMAN relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001422 ! CLAP2_HUMAN relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001426 ! CC45L_HUMAN relationship: has_participant CCO:B0001427 ! KTNA1_HUMAN relationship: has_participant CCO:B0001429 ! E2F6_HUMAN relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0001435 ! CD123_HUMAN relationship: has_participant CCO:B0001438 ! TUSC2_HUMAN relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0001440 ! DCTN3_HUMAN relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0001444 ! SASH1_HUMAN relationship: has_participant CCO:B0001446 ! CCNB2_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0001452 ! O95648_HUMAN relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001455 ! RECK_HUMAN relationship: has_participant CCO:B0001457 ! PTTG1_HUMAN relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001479 ! ANXA1_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0001496 ! FUMH_HUMAN relationship: has_participant CCO:B0001510 ! IRF1_HUMAN relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001534 ! DNLI1_HUMAN relationship: has_participant CCO:B0001536 ! WT1_HUMAN relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0001549 ! CRCM_HUMAN relationship: has_participant CCO:B0001550 ! KTHY_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001552 ! GA45A_HUMAN relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0001561 ! G0S2_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001566 ! DUS1_HUMAN relationship: has_participant CCO:B0001567 ! RBL1_HUMAN relationship: has_participant CCO:B0001568 ! EPHB2_HUMAN relationship: has_participant CCO:B0001573 ! CCND2_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0001577 ! MPIP2_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001582 ! MK04_HUMAN relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0001596 ! PP1G_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0001602 ! CCNF_HUMAN relationship: has_participant CCO:B0001604 ! CETN2_HUMAN relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0001607 ! NBL1_HUMAN relationship: has_participant CCO:B0001614 ! CNDD3_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0001619 ! DCC_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0001622 ! KI67_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001626 ! NASP_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001636 ! FHIT_HUMAN relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0001638 ! DNLI3_HUMAN relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001645 ! KNTC1_HUMAN relationship: has_participant CCO:B0001646 ! RASF2_HUMAN relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001652 ! CCNH_HUMAN relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001655 ! NEK4_HUMAN relationship: has_participant CCO:B0001656 ! CCNG1_HUMAN relationship: has_participant CCO:B0001659 ! KIF11_HUMAN relationship: has_participant CCO:B0001660 ! RBM5_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0001665 ! MK12_HUMAN relationship: has_participant CCO:B0001666 ! HRSL3_HUMAN relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001668 ! PMS1_HUMAN relationship: has_participant CCO:B0001669 ! PMS2_HUMAN relationship: has_participant CCO:B0001672 ! GAS1_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0001684 ! MLF1_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001688 ! PP1A_HUMAN relationship: has_participant CCO:B0001689 ! PP1B_HUMAN relationship: has_participant CCO:B0001692 ! RHOB_HUMAN relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0001698 ! MORN_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0001702 ! TXN4A_HUMAN relationship: has_participant CCO:B0001706 ! FOXO4_HUMAN relationship: has_participant CCO:B0001707 ! CDK3_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0001715 ! CENPE_HUMAN relationship: has_participant CCO:B0001716 ! KIF23_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0001725 ! RBL2_HUMAN relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0001729 ! CT069_HUMAN relationship: has_participant CCO:B0001731 ! CETN1_HUMAN relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001733 ! CDC20_HUMAN relationship: has_participant CCO:B0001737 ! STRN3_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0001740 ! CSN1_HUMAN relationship: has_participant CCO:B0001742 ! CAF1A_HUMAN relationship: has_participant CCO:B0001743 ! CAF1B_HUMAN relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0001756 ! ATR_HUMAN relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0001763 ! CUL4B_HUMAN relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0001765 ! PTC1_HUMAN relationship: has_participant CCO:B0001775 ! SEPT6_HUMAN relationship: has_participant CCO:B0001776 ! TFDP1_HUMAN relationship: has_participant CCO:B0001777 ! TFDP2_HUMAN relationship: has_participant CCO:B0001781 ! E2F2_HUMAN relationship: has_participant CCO:B0001782 ! CASL_HUMAN relationship: has_participant CCO:B0001783 ! HIC1_HUMAN relationship: has_participant CCO:B0001784 ! DMC1_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0001788 ! MDC1_HUMAN relationship: has_participant CCO:B0001789 ! KANK1_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001793 ! NOLC1_HUMAN relationship: has_participant CCO:B0001796 ! HECAM_HUMAN relationship: has_participant CCO:B0001797 ! CND2_HUMAN relationship: has_participant CCO:B0001798 ! FL2D_HUMAN relationship: has_participant CCO:B0001800 ! SEPT2_HUMAN relationship: has_participant CCO:B0001801 ! CND1_HUMAN relationship: has_participant CCO:B0001807 ! DLGP5_HUMAN relationship: has_participant CCO:B0001808 ! SYCP1_HUMAN relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0001812 ! MARE1_HUMAN relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001816 ! SEPT7_HUMAN relationship: has_participant CCO:B0001817 ! E2F4_HUMAN relationship: has_participant CCO:B0001818 ! EXT1_HUMAN relationship: has_participant CCO:B0001821 ! CCNG2_HUMAN relationship: has_participant CCO:B0001822 ! MK06_HUMAN relationship: has_participant CCO:B0001823 ! CDKN3_HUMAN relationship: has_participant CCO:B0001827 ! Q1WWK5_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001831 ! Q3LRW5_HUMAN relationship: has_participant CCO:B0001832 ! TBRG1_HUMAN relationship: has_participant CCO:B0001834 ! MAP9_HUMAN relationship: has_participant CCO:B0001836 ! PDCD4_HUMAN relationship: has_participant CCO:B0001837 ! CEP55_HUMAN relationship: has_participant CCO:B0001838 ! PKHO1_HUMAN relationship: has_participant CCO:B0001839 ! BOREA_HUMAN relationship: has_participant CCO:B0001840 ! SGOL2_HUMAN relationship: has_participant CCO:B0001841 ! ESCO2_HUMAN relationship: has_participant CCO:B0001845 ! Q59FW7_HUMAN relationship: has_participant CCO:B0001846 ! Q59GE1_HUMAN relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0001848 ! ESCO1_HUMAN relationship: has_participant CCO:B0001861 ! SPDYC_HUMAN relationship: has_participant CCO:B0001862 ! SPDYA_HUMAN relationship: has_participant CCO:B0001867 ! Q5T179_HUMAN relationship: has_participant CCO:B0001879 ! AVPI1_HUMAN relationship: has_participant CCO:B0001883 ! QN1_HUMAN relationship: has_participant CCO:B0001894 ! LIN9_HUMAN relationship: has_participant CCO:B0001895 ! CROCC_HUMAN relationship: has_participant CCO:B0001896 ! Q5TZP9_HUMAN relationship: has_participant CCO:B0001897 ! RIF1_HUMAN relationship: has_participant CCO:B0001899 ! DAB2P_HUMAN relationship: has_participant CCO:B0001901 ! Q5W161_HUMAN relationship: has_participant CCO:B0001902 ! POLS_HUMAN relationship: has_participant CCO:B0001903 ! STEA3_HUMAN relationship: has_participant CCO:B0001904 ! KCD11_HUMAN relationship: has_participant CCO:B0001905 ! CDCA2_HUMAN relationship: has_participant CCO:B0001906 ! CYTSA_HUMAN relationship: has_participant CCO:B0001908 ! NIPBL_HUMAN relationship: has_participant CCO:B0001909 ! RINT1_HUMAN relationship: has_participant CCO:B0001910 ! Q6NVV2_HUMAN relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0001913 ! L2GL2_HUMAN relationship: has_participant CCO:B0001914 ! BORA_HUMAN relationship: has_participant CCO:B0001915 ! SYCE2_HUMAN relationship: has_participant CCO:B0001916 ! DCR1A_HUMAN relationship: has_participant CCO:B0001918 ! SAS6_HUMAN relationship: has_participant CCO:B0001922 ! TM11A_HUMAN relationship: has_participant CCO:B0001925 ! SEP14_HUMAN relationship: has_participant CCO:B0001930 ! MAEA_HUMAN relationship: has_participant CCO:B0001931 ! VASH1_HUMAN relationship: has_participant CCO:B0001932 ! STRAD_HUMAN relationship: has_participant CCO:B0001933 ! CLAP1_HUMAN relationship: has_participant CCO:B0001935 ! Q7Z774_HUMAN relationship: has_participant CCO:B0001939 ! TLK2_HUMAN relationship: has_participant CCO:B0001940 ! CUZD1_HUMAN relationship: has_participant CCO:B0001941 ! NIPA_HUMAN relationship: has_participant CCO:B0001943 ! CNDG2_HUMAN relationship: has_participant CCO:B0001946 ! SIAH1_HUMAN relationship: has_participant CCO:B0001947 ! EGFL6_HUMAN relationship: has_participant CCO:B0001950 ! CCAR1_HUMAN relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0001952 ! RM41_HUMAN relationship: has_participant CCO:B0001954 ! XRN1_HUMAN relationship: has_participant CCO:B0001955 ! CCRK_HUMAN relationship: has_participant CCO:B0001956 ! ASPM_HUMAN relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: has_participant CCO:B0001959 ! TAF1L_HUMAN relationship: has_participant CCO:B0001960 ! SYCE1_HUMAN relationship: has_participant CCO:B0001961 ! CNTRB_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0001963 ! KIF2B_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0001969 ! Q8N855_HUMAN relationship: has_participant CCO:B0001971 ! BANP_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0001975 ! PAPD5_HUMAN relationship: has_participant CCO:B0001976 ! RCBT1_HUMAN relationship: has_participant CCO:B0001977 ! SMC1B_HUMAN relationship: has_participant CCO:B0001978 ! PPC1B_HUMAN relationship: has_participant CCO:B0001980 ! DP13B_HUMAN relationship: has_participant CCO:B0001981 ! FLCN_HUMAN relationship: has_participant CCO:B0001983 ! CADM4_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN relationship: has_participant CCO:B0001986 ! CDC26_HUMAN relationship: has_participant CCO:B0001987 ! G45IP_HUMAN relationship: has_participant CCO:B0001989 ! UBA3_HUMAN relationship: has_participant CCO:B0001991 ! NEK9_HUMAN relationship: has_participant CCO:B0001994 ! CABL1_HUMAN relationship: has_participant CCO:B0001995 ! RBCC1_HUMAN relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0001997 ! PAR3L_HUMAN relationship: has_participant CCO:B0001999 ! HASP_HUMAN relationship: has_participant CCO:B0002000 ! TUSC4_HUMAN relationship: has_participant CCO:B0002001 ! Q8WUE3_HUMAN relationship: has_participant CCO:B0002003 ! SKA2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002005 ! PCNP_HUMAN relationship: has_participant CCO:B0002006 ! CKAP2_HUMAN relationship: has_participant CCO:B0002007 ! CCNB3_HUMAN relationship: has_participant CCO:B0002008 ! RASF5_HUMAN relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0002015 ! SEPT8_HUMAN relationship: has_participant CCO:B0002017 ! DDX12_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0002026 ! NAT6_HUMAN relationship: has_participant CCO:B0002028 ! EXT2_HUMAN relationship: has_participant CCO:B0002029 ! TP4A1_HUMAN relationship: has_participant CCO:B0002031 ! E2F7_HUMAN relationship: has_participant CCO:B0002032 ! SKA1_HUMAN relationship: has_participant CCO:B0002033 ! PINX1_HUMAN relationship: has_participant CCO:B0002034 ! CCDC5_HUMAN relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0002037 ! DDX11_HUMAN relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN relationship: has_participant CCO:B0002041 ! SENP5_HUMAN relationship: has_participant CCO:B0002042 ! SGSM3_HUMAN relationship: has_participant CCO:B0002043 ! NSL1_HUMAN relationship: has_participant CCO:B0002047 ! LMLN_HUMAN relationship: has_participant CCO:B0002050 ! Q96MY5_HUMAN relationship: has_participant CCO:B0002051 ! ZN830_HUMAN relationship: has_participant CCO:B0002054 ! UHRF2_HUMAN relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0002056 ! MPPH1_HUMAN relationship: has_participant CCO:B0002057 ! Q96Q97_HUMAN relationship: has_participant CCO:B0002058 ! SPAG5_HUMAN relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0002063 ! UHRF1_HUMAN relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0002070 ! ZWIA_HUMAN relationship: has_participant CCO:B0002072 ! MPP8_HUMAN relationship: has_participant CCO:B0002076 ! CDCA3_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN relationship: has_participant CCO:B0002079 ! Q99648_HUMAN relationship: has_participant CCO:B0002081 ! CGRE1_HUMAN relationship: has_participant CCO:B0002082 ! CGRF1_HUMAN relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002090 ! SPI2A_HUMAN relationship: has_participant CCO:B0002092 ! CND3_HUMAN relationship: has_participant CCO:B0002093 ! SPI2B_HUMAN relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0002095 ! APC13_HUMAN relationship: has_participant CCO:B0002097 ! CABL2_HUMAN relationship: has_participant CCO:B0002098 ! HTAI2_HUMAN relationship: has_participant CCO:B0002099 ! CP250_HUMAN relationship: has_participant CCO:B0002100 ! KTNB1_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: has_participant CCO:B0002105 ! KIFC1_HUMAN relationship: has_participant CCO:B0002106 ! SYCP2_HUMAN relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: has_participant CCO:B0002109 ! FACD2_HUMAN relationship: has_participant CCO:B0002110 ! CADM1_HUMAN relationship: has_participant CCO:B0002112 ! PAR6G_HUMAN relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002117 ! DPH1_HUMAN relationship: has_participant CCO:B0002118 ! Q9BZU3_HUMAN relationship: has_participant CCO:B0002119 ! STRAB_HUMAN relationship: has_participant CCO:B0002122 ! MIS12_HUMAN relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN relationship: has_participant CCO:B0002125 ! APC1_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN relationship: has_participant CCO:B0002128 ! TSYL2_HUMAN relationship: has_participant CCO:B0002129 ! RASF4_HUMAN relationship: has_participant CCO:B0002131 ! PININ_HUMAN relationship: has_participant CCO:B0002132 ! Q9H315_HUMAN relationship: has_participant CCO:B0002133 ! TXNIP_HUMAN relationship: has_participant CCO:B0002134 ! DSN1_HUMAN relationship: has_participant CCO:B0002137 ! RGC32_HUMAN relationship: has_participant CCO:B0002139 ! SUV92_HUMAN relationship: has_participant CCO:B0002142 ! CLSPN_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0002148 ! CHM1A_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0002153 ! CYLD_HUMAN relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0002155 ! ANLN_HUMAN relationship: has_participant CCO:B0002156 ! BIN3_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0002161 ! HELLS_HUMAN relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0002166 ! Q9NSH2_HUMAN relationship: has_participant CCO:B0002168 ! SMC4_HUMAN relationship: has_participant CCO:B0002169 ! SEP11_HUMAN relationship: has_participant CCO:B0002170 ! FANCI_HUMAN relationship: has_participant CCO:B0002172 ! TXN4B_HUMAN relationship: has_participant CCO:B0002173 ! NDE1_HUMAN relationship: has_participant CCO:B0002175 ! NSMA2_HUMAN relationship: has_participant CCO:B0002177 ! APC11_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0002181 ! WWOX_HUMAN relationship: has_participant CCO:B0002182 ! SH3B4_HUMAN relationship: has_participant CCO:B0002183 ! SEP10_HUMAN relationship: has_participant CCO:B0002184 ! HM20B_HUMAN relationship: has_participant CCO:B0002186 ! RCC2_HUMAN relationship: has_participant CCO:B0002187 ! BCCIP_HUMAN relationship: has_participant CCO:B0002188 ! RHG20_HUMAN relationship: has_participant CCO:B0002189 ! DEC1_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN relationship: has_participant CCO:B0002194 ! DBF4A_HUMAN relationship: has_participant CCO:B0002197 ! DMBT1_HUMAN relationship: has_participant CCO:B0002198 ! SEPT3_HUMAN relationship: has_participant CCO:B0002201 ! SEPT9_HUMAN relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0002205 ! MUTYH_HUMAN relationship: has_participant CCO:B0002209 ! STAG3_HUMAN relationship: has_participant CCO:B0002210 ! MCM8_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002213 ! APC7_HUMAN relationship: has_participant CCO:B0002214 ! APC5_HUMAN relationship: has_participant CCO:B0002215 ! APC4_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN relationship: has_participant CCO:B0002217 ! ING1_HUMAN relationship: has_participant CCO:B0002219 ! DP13A_HUMAN relationship: has_participant CCO:B0002220 ! TLK1_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN relationship: has_participant CCO:B0002224 ! MTUS1_HUMAN relationship: has_participant CCO:B0002225 ! CCPG1_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0002229 ! FZR_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0002233 ! CC14A_HUMAN relationship: has_participant CCO:B0002234 ! ING4_HUMAN relationship: has_participant CCO:B0002235 ! TIM_HUMAN relationship: has_participant CCO:B0002238 ! MARE3_HUMAN relationship: has_participant CCO:B0002241 ! CD2L2_HUMAN relationship: has_participant CCO:B0002242 ! AURKC_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0002245 ! JAG2_HUMAN relationship: has_participant CCO:B0002247 ! DLEC1_HUMAN relationship: has_participant CCO:B0002248 ! LZTS1_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0002250 ! NUDC_HUMAN relationship: has_participant CCO:B0002253 ! STA13_HUMAN relationship: has_participant CCO:B0002254 ! RBGP1_HUMAN relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN relationship: has_participant CCO:B0002259 ! UBP16_HUMAN relationship: has_participant CCO:B0002262 ! SPIN1_HUMAN relationship: has_participant CCO:B0002263 ! EID1_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0022296 ! Q3LRW1_HUMAN relationship: has_participant CCO:B0022298 ! Q3LRW4_HUMAN relationship: has_participant CCO:B0022308 ! Q1MSW9_HUMAN relationship: has_participant CCO:B0022312 ! Q3LRW3_HUMAN relationship: has_participant CCO:B0023340 ! Q59H84_HUMAN relationship: has_participant CCO:B0023347 ! Q9H9P7_HUMAN relationship: has_participant CCO:B0023348 ! Q8NFH9_HUMAN relationship: has_participant CCO:B0023351 ! Q6B514_HUMAN relationship: has_participant CCO:B0023650 ! Q53QU3_HUMAN relationship: has_participant CCO:B0026249 ! ZMY11_HUMAN relationship: has_participant CCO:B0026250 ! Q5JXL7_HUMAN relationship: has_participant CCO:B0026252 ! NOXIN_HUMAN relationship: has_participant CCO:B0026253 ! SEP12_HUMAN relationship: has_participant CCO:B0026254 ! JUB_HUMAN relationship: has_participant CCO:B0026257 ! PDS5B_HUMAN relationship: has_participant CCO:B0028285 ! SEP13_HUMAN relationship: has_participant CCO:B0030400 ! A8K7M3_HUMAN relationship: has_participant CCO:B0032821 ! ZWILC_HUMAN relationship: has_participant CCO:B0033478 ! DBF4B_HUMAN relationship: has_participant CCO:B0033797 ! Q548C9_HUMAN relationship: has_participant CCO:B0033798 ! Q541S4_HUMAN relationship: has_participant CCO:B0035936 ! RNF8_HUMAN relationship: has_participant CCO:B0035938 ! SETD8_HUMAN relationship: has_participant CCO:B0035939 ! C8AP2_HUMAN relationship: has_participant CCO:B0039945 ! CRBL2_HUMAN relationship: has_participant CCO:B0039946 ! NPAT_HUMAN relationship: has_participant CCO:B0039949 ! FSD1_HUMAN relationship: has_participant CCO:B0039950 ! DCC1_HUMAN relationship: has_participant CCO:B0041227 ! B1AHR1_HUMAN relationship: has_participant CCO:B0041234 ! B1AMS2_HUMAN relationship: has_participant CCO:B0041241 ! CCDB1_HUMAN relationship: has_participant CCO:B0041249 ! HMGA2_HUMAN relationship: has_participant CCO:B0041254 ! PTOR1_HUMAN relationship: has_participant CCO:B0041256 ! ERC6L_HUMAN relationship: has_participant CCO:B0041257 ! E4F1_HUMAN relationship: has_participant CCO:B0041258 ! XAF1_HUMAN relationship: has_participant CCO:B0041260 ! CP110_HUMAN relationship: has_participant CCO:B0041261 ! ERF3B_HUMAN relationship: has_participant CCO:B0041262 ! CTF8_HUMAN relationship: has_participant CCO:B0041264 ! PRDBP_HUMAN relationship: has_participant CCO:B0041265 ! MTBP_HUMAN relationship: has_participant CCO:B0041266 ! CINP_HUMAN relationship: has_participant CCO:B0041267 ! DMTF1_HUMAN relationship: has_participant CCO:B0041710 ! B1AHR2_HUMAN relationship: has_participant CCO:B0043816 ! ZBT7C_HUMAN relationship: has_participant CCO:B0043820 ! AIM2_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: has_participant CCO:B0043828 ! IFIX_HUMAN relationship: has_participant CCO:B0043829 ! PSRC1_HUMAN relationship: has_participant CCO:B0043832 ! MLL5_HUMAN relationship: has_participant CCO:B0043833 ! SC5A8_HUMAN relationship: has_participant CCO:B0043834 ! URG4_HUMAN relationship: has_participant CCO:B0043835 ! CTF18_HUMAN relationship: has_participant CCO:B0043837 ! ST20_HUMAN [Term] id: CCO:P0000067 name: cell cycle arrest namespace: biological_process def: "The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M)." [GOC:dph, GOC:mah, GOC:tb] synonym: "arrest of cell cycle progression" EXACT [] synonym: "cessation of cell cycle" EXACT [] synonym: "termination of cell cycle" EXACT [] xref: GO:0007050 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001333 ! A6NK88_HUMAN relationship: has_participant CCO:B0001343 ! A7KMP4_HUMAN relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0001375 ! PPM1G_HUMAN relationship: has_participant CCO:B0001388 ! SNUT1_HUMAN relationship: has_participant CCO:B0001401 ! GAS2_HUMAN relationship: has_participant CCO:B0001407 ! HBP1_HUMAN relationship: has_participant CCO:B0001409 ! DBC1_HUMAN relationship: has_participant CCO:B0001417 ! GAS7_HUMAN relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001428 ! ERN1_HUMAN relationship: has_participant CCO:B0001435 ! CD123_HUMAN relationship: has_participant CCO:B0001436 ! PR15A_HUMAN relationship: has_participant CCO:B0001443 ! BPAEA_HUMAN relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001484 ! IFNW1_HUMAN relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001504 ! IL8_HUMAN relationship: has_participant CCO:B0001552 ! GA45A_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0001665 ! MK12_HUMAN relationship: has_participant CCO:B0001672 ! GAS1_HUMAN relationship: has_participant CCO:B0001673 ! AIF1_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001681 ! SESN2_HUMAN relationship: has_participant CCO:B0001682 ! SESN3_HUMAN relationship: has_participant CCO:B0001684 ! MLF1_HUMAN relationship: has_participant CCO:B0001699 ! IF4G2_HUMAN relationship: has_participant CCO:B0001706 ! FOXO4_HUMAN relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0001757 ! PKD2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0001760 ! CUL2_HUMAN relationship: has_participant CCO:B0001761 ! CUL3_HUMAN relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001796 ! HECAM_HUMAN relationship: has_participant CCO:B0001806 ! DHC24_HUMAN relationship: has_participant CCO:B0001814 ! STK11_HUMAN relationship: has_participant CCO:B0001823 ! CDKN3_HUMAN relationship: has_participant CCO:B0001832 ! TBRG1_HUMAN relationship: has_participant CCO:B0001872 ! Q5T317_HUMAN relationship: has_participant CCO:B0001884 ! Q5TBT1_HUMAN relationship: has_participant CCO:B0001885 ! Q5TBT2_HUMAN relationship: has_participant CCO:B0001924 ! Q6ZQZ4_HUMAN relationship: has_participant CCO:B0001928 ! ERN2_HUMAN relationship: has_participant CCO:B0001931 ! VASH1_HUMAN relationship: has_participant CCO:B0001944 ! GA2L3_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0001985 ! GA2L2_HUMAN relationship: has_participant CCO:B0001988 ! UHMK1_HUMAN relationship: has_participant CCO:B0001998 ! Q8TEY4_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0002027 ! CUL5_HUMAN relationship: has_participant CCO:B0002030 ! TBRG4_HUMAN relationship: has_participant CCO:B0002042 ! SGSM3_HUMAN relationship: has_participant CCO:B0002048 ! Q96LE1_HUMAN relationship: has_participant CCO:B0002053 ! MACF4_HUMAN relationship: has_participant CCO:B0002056 ! MPPH1_HUMAN relationship: has_participant CCO:B0002060 ! NEB2_HUMAN relationship: has_participant CCO:B0002067 ! GA2L1_HUMAN relationship: has_participant CCO:B0002081 ! CGRE1_HUMAN relationship: has_participant CCO:B0002082 ! CGRF1_HUMAN relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0002096 ! Q9BSP9_HUMAN relationship: has_participant CCO:B0002121 ! Q9GZT1_HUMAN relationship: has_participant CCO:B0002141 ! Q9H8U2_HUMAN relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0002174 ! BTG4_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0002231 ! PLAL1_HUMAN relationship: has_participant CCO:B0002234 ! ING4_HUMAN relationship: has_participant CCO:B0002237 ! MACF1_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0002258 ! P2R3B_HUMAN relationship: has_participant CCO:B0002266 ! SESN1_HUMAN relationship: has_participant CCO:B0025035 ! Q7Z324_HUMAN relationship: has_participant CCO:B0026252 ! NOXIN_HUMAN relationship: has_participant CCO:B0026256 ! RPRM_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0040022 ! JMY_HUMAN relationship: has_participant CCO:B0041233 ! B1ALC7_HUMAN relationship: has_participant CCO:B0041235 ! B1ANQ7_HUMAN relationship: has_participant CCO:B0041236 ! B1ANR2_HUMAN relationship: has_participant CCO:B0041265 ! MTBP_HUMAN relationship: has_participant CCO:B0043819 ! B2D1N3_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0043832 ! MLL5_HUMAN [Term] id: CCO:P0000068 name: mitotic spindle organization and biogenesis namespace: biological_process def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." [GOC:mah] synonym: "mitotic spindle organisation and biogenesis" EXACT [] synonym: "spindle organization and biogenesis during mitosis" EXACT [] xref: GO:0007052 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000385 ! spindle organization and biogenesis relationship: has_participant CCO:B0001528 ! STMN1_HUMAN relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001587 ! TTK_HUMAN relationship: has_participant CCO:B0001659 ! KIF11_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0001780 ! DYHC1_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0002199 ! UN84B_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: part_of CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000069 name: spindle assembly involved in male meiosis namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah] synonym: "male meiotic spindle assembly (sensu Metazoa)" RELATED [] xref: GO:0007053 is_a: CCO:P0000392 ! spindle assembly relationship: part_of CCO:P0000131 ! male meiosis [Term] id: CCO:P0000070 name: spindle assembly involved in male meiosis I namespace: biological_process def: "The formation of the spindle during meiosis I of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah] synonym: "male meiosis I spindle assembly (sensu Metazoa)" RELATED [] xref: GO:0007054 is_a: CCO:P0000069 ! spindle assembly involved in male meiosis relationship: part_of CCO:P0000132 ! male meiosis I [Term] id: CCO:P0000071 name: spindle assembly involved male meiosis II namespace: biological_process def: "The formation of the spindle during meiosis II of a meiotic cell cycle in males. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah] synonym: "male meiosis II spindle assembly (sensu Metazoa)" RELATED [] xref: GO:0007055 is_a: CCO:P0000069 ! spindle assembly involved in male meiosis relationship: part_of CCO:P0000133 ! male meiosis II [Term] id: CCO:P0000072 name: spindle assembly involved in female meiosis namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah] synonym: "female meiotic spindle assembly (sensu Metazoa)" RELATED [] xref: GO:0007056 is_a: CCO:P0000392 ! spindle assembly relationship: part_of CCO:P0000134 ! female meiosis [Term] id: CCO:P0000073 name: spindle assembly involved in female meiosis I namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah] synonym: "female meiosis I spindle assembly (sensu Metazoa)" RELATED [] xref: GO:0007057 is_a: CCO:P0000072 ! spindle assembly involved in female meiosis relationship: part_of CCO:P0000135 ! female meiosis I [Term] id: CCO:P0000074 name: spindle assembly involved in female meiosis II namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. As in, but not restricted to, the multicellular animals (Metazoa, ncbi_taxonomy_id:33208)." [GOC:mah] synonym: "female meiosis II spindle assembly (sensu Metazoa)" RELATED [] xref: GO:0007058 is_a: CCO:P0000072 ! spindle assembly involved in female meiosis relationship: part_of CCO:P0000137 ! female meiosis II [Term] id: CCO:P0000075 name: male meiosis chromosome segregation namespace: biological_process def: "The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male." [GOC:ai] xref: GO:0007060 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000237 ! meiotic chromosome segregation relationship: part_of CCO:P0000131 ! male meiosis [Term] id: CCO:P0000076 name: sister chromatid cohesion namespace: biological_process def: "The cell cycle process by which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome." [GOC:mah, ISBN:0815316194] xref: GO:0007062 xref: Reactome:163048 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001447 ! REC8_HUMAN relationship: has_participant CCO:B0001902 ! POLS_HUMAN relationship: has_participant CCO:B0001977 ! SMC1B_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: part_of CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0000077 name: regulation of sister chromatid cohesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid cohesion." [GOC:go_curators] xref: GO:0007063 is_a: CCO:P0000382 ! regulation of cell cycle process is_a: CCO:P0001766 ! regulation of chromosome organization and biogenesis relationship: regulates CCO:P0000076 ! sister chromatid cohesion [Term] id: CCO:P0000078 name: mitotic sister chromatid cohesion namespace: biological_process def: "The cell cycle process whereby the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission." [GOC:ai, GOC:rn, PMID:10827941, PMID:11389843, PMID:14623866] xref: GO:0007064 is_a: CCO:P0000076 ! sister chromatid cohesion relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0026257 ! PDS5B_HUMAN relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000079 name: male meiosis sister chromatid cohesion namespace: biological_process def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male." [GOC:ai] xref: GO:0007065 is_a: CCO:P0000289 ! meiotic sister chromatid cohesion relationship: part_of CCO:P0000131 ! male meiosis [Term] id: CCO:P0000080 name: female meiosis sister chromatid cohesion namespace: biological_process def: "The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female." [GOC:ai] xref: GO:0007066 is_a: CCO:P0000289 ! meiotic sister chromatid cohesion relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: part_of CCO:P0000134 ! female meiosis [Term] id: CCO:P0000081 name: mitosis namespace: biological_process def: "Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:ma, ISBN:0198547684] xref: GO:0007067 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001321 ! A6NE16_HUMAN relationship: has_participant CCO:B0001334 ! SAC31_HUMAN relationship: has_participant CCO:B0001340 ! A6NMK2_HUMAN relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001356 ! CTRO_HUMAN relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001361 ! O14835_HUMAN relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001395 ! BUB1_HUMAN relationship: has_participant CCO:B0001396 ! BUB3_HUMAN relationship: has_participant CCO:B0001399 ! AKAP8_HUMAN relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001422 ! CLAP2_HUMAN relationship: has_participant CCO:B0001427 ! KTNA1_HUMAN relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0001440 ! DCTN3_HUMAN relationship: has_participant CCO:B0001446 ! CCNB2_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001457 ! PTTG1_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001518 ! HGF_HUMAN relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0001577 ! MPIP2_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001580 ! CLIP1_HUMAN relationship: has_participant CCO:B0001602 ! CCNF_HUMAN relationship: has_participant CCO:B0001604 ! CETN2_HUMAN relationship: has_participant CCO:B0001614 ! CNDD3_HUMAN relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001645 ! KNTC1_HUMAN relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001655 ! NEK4_HUMAN relationship: has_participant CCO:B0001656 ! CCNG1_HUMAN relationship: has_participant CCO:B0001659 ! KIF11_HUMAN relationship: has_participant CCO:B0001662 ! PPP5_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0001698 ! MORN_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0001702 ! TXN4A_HUMAN relationship: has_participant CCO:B0001707 ! CDK3_HUMAN relationship: has_participant CCO:B0001715 ! CENPE_HUMAN relationship: has_participant CCO:B0001716 ! KIF23_HUMAN relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0001731 ! CETN1_HUMAN relationship: has_participant CCO:B0001733 ! CDC20_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0001754 ! TBB3_HUMAN relationship: has_participant CCO:B0001769 ! TBB2A_HUMAN relationship: has_participant CCO:B0001779 ! DCTN1_HUMAN relationship: has_participant CCO:B0001782 ! CASL_HUMAN relationship: has_participant CCO:B0001786 ! Q14569_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001792 ! KIF22_HUMAN relationship: has_participant CCO:B0001793 ! NOLC1_HUMAN relationship: has_participant CCO:B0001797 ! CND2_HUMAN relationship: has_participant CCO:B0001801 ! CND1_HUMAN relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0001812 ! MARE1_HUMAN relationship: has_participant CCO:B0001821 ! CCNG2_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001834 ! MAP9_HUMAN relationship: has_participant CCO:B0001837 ! CEP55_HUMAN relationship: has_participant CCO:B0001839 ! BOREA_HUMAN relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0001883 ! QN1_HUMAN relationship: has_participant CCO:B0001902 ! POLS_HUMAN relationship: has_participant CCO:B0001905 ! CDCA2_HUMAN relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0001914 ! BORA_HUMAN relationship: has_participant CCO:B0001916 ! DCR1A_HUMAN relationship: has_participant CCO:B0001926 ! Q6ZV00_HUMAN relationship: has_participant CCO:B0001933 ! CLAP1_HUMAN relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0001941 ! NIPA_HUMAN relationship: has_participant CCO:B0001942 ! HORM1_HUMAN relationship: has_participant CCO:B0001943 ! CNDG2_HUMAN relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0001956 ! ASPM_HUMAN relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: has_participant CCO:B0001958 ! Q8IZX3_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0001963 ! KIF2B_HUMAN relationship: has_participant CCO:B0001967 ! HORM2_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0001975 ! PAPD5_HUMAN relationship: has_participant CCO:B0001986 ! CDC26_HUMAN relationship: has_participant CCO:B0001991 ! NEK9_HUMAN relationship: has_participant CCO:B0002003 ! SKA2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0002032 ! SKA1_HUMAN relationship: has_participant CCO:B0002034 ! CCDC5_HUMAN relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN relationship: has_participant CCO:B0002043 ! NSL1_HUMAN relationship: has_participant CCO:B0002045 ! TOPK_HUMAN relationship: has_participant CCO:B0002047 ! LMLN_HUMAN relationship: has_participant CCO:B0002051 ! ZN830_HUMAN relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0002056 ! MPPH1_HUMAN relationship: has_participant CCO:B0002058 ! SPAG5_HUMAN relationship: has_participant CCO:B0002076 ! CDCA3_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN relationship: has_participant CCO:B0002080 ! KIF2C_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002092 ! CND3_HUMAN relationship: has_participant CCO:B0002095 ! APC13_HUMAN relationship: has_participant CCO:B0002100 ! KTNB1_HUMAN relationship: has_participant CCO:B0002101 ! TBB2B_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: has_participant CCO:B0002105 ! KIFC1_HUMAN relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002122 ! MIS12_HUMAN relationship: has_participant CCO:B0002125 ! APC1_HUMAN relationship: has_participant CCO:B0002134 ! DSN1_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN relationship: has_participant CCO:B0002144 ! EMAL4_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0002155 ! ANLN_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0002161 ! HELLS_HUMAN relationship: has_participant CCO:B0002165 ! KIF15_HUMAN relationship: has_participant CCO:B0002168 ! SMC4_HUMAN relationship: has_participant CCO:B0002172 ! TXN4B_HUMAN relationship: has_participant CCO:B0002173 ! NDE1_HUMAN relationship: has_participant CCO:B0002177 ! APC11_HUMAN relationship: has_participant CCO:B0002186 ! RCC2_HUMAN relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002213 ! APC7_HUMAN relationship: has_participant CCO:B0002214 ! APC5_HUMAN relationship: has_participant CCO:B0002215 ! APC4_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN relationship: has_participant CCO:B0002227 ! TPX2_HUMAN relationship: has_participant CCO:B0002229 ! FZR_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0002235 ! TIM_HUMAN relationship: has_participant CCO:B0002238 ! MARE3_HUMAN relationship: has_participant CCO:B0002241 ! CD2L2_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0002250 ! NUDC_HUMAN relationship: has_participant CCO:B0002252 ! SUGT1_HUMAN relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0026257 ! PDS5B_HUMAN relationship: has_participant CCO:B0032821 ! ZWILC_HUMAN relationship: has_participant CCO:B0035936 ! RNF8_HUMAN relationship: has_participant CCO:B0035938 ! SETD8_HUMAN relationship: has_participant CCO:B0039949 ! FSD1_HUMAN relationship: has_participant CCO:B0041228 ! B1AK43_HUMAN relationship: has_participant CCO:B0041229 ! B1AK44_HUMAN relationship: has_participant CCO:B0041230 ! B1AK45_HUMAN relationship: has_participant CCO:B0041231 ! B1AK46_HUMAN relationship: has_participant CCO:B0041232 ! B1AK47_HUMAN relationship: has_participant CCO:B0041237 ! B1AQT3_HUMAN relationship: has_participant CCO:B0041238 ! B1AQT4_HUMAN relationship: has_participant CCO:B0041249 ! HMGA2_HUMAN relationship: has_participant CCO:B0041256 ! ERC6L_HUMAN relationship: has_participant CCO:B0041257 ! E4F1_HUMAN relationship: part_of CCO:P0000017 ! M phase of mitotic cell cycle [Term] id: CCO:P0000082 name: negative regulation of transcription, mitotic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription during mitosis." [GOC:go_curators] synonym: "down regulation of transcription, mitotic" EXACT [] synonym: "down-regulation of transcription, mitotic" EXACT [] synonym: "downregulation of transcription, mitotic" EXACT [] synonym: "inhibition of transcription, mitotic" NARROW [] synonym: "mitotic repression of transcription" EXACT [] xref: GO:0007068 is_a: CCO:P0000256 ! regulation of transcription, mitotic is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:P0000083 name: negative regulation of transcription from RNA polymerase I promoter, mitotic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators] synonym: "down regulation of transcription from RNA polymerase I promoter, mitotic" EXACT [] synonym: "down-regulation of transcription from RNA polymerase I promoter, mitotic" EXACT [] synonym: "downregulation of transcription from RNA polymerase I promoter, mitotic" EXACT [] synonym: "inhibition of transcription from RNA polymerase I promoter, mitotic" NARROW [] synonym: "mitotic repression of transcription from Pol I promoter" EXACT [] synonym: "negative regulation of transcription from Pol I promoter, mitotic" EXACT [] xref: GO:0007069 is_a: CCO:P0000082 ! negative regulation of transcription, mitotic is_a: CCO:P0000266 ! regulation of transcription from RNA polymerase I promoter, mitotic is_a: CCO:P0001127 ! negative regulation of transcription from RNA polymerase I promoter [Term] id: CCO:P0000084 name: negative regulation of transcription from RNA polymerase II promoter, mitotic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators] synonym: "down regulation of transcription from RNA polymerase II promoter, mitotic" EXACT [] synonym: "down-regulation of transcription from RNA polymerase II promoter, mitotic" EXACT [] synonym: "downregulation of transcription from RNA polymerase II promoter, mitotic" EXACT [] synonym: "inhibition of transcription from RNA polymerase II promoter, mitotic" NARROW [] synonym: "mitotic repression of transcription from Pol II promoter" EXACT [] synonym: "negative regulation of transcription from Pol II promoter, mitotic" EXACT [] xref: GO:0007070 is_a: CCO:P0000082 ! negative regulation of transcription, mitotic is_a: CCO:P0000268 ! regulation of transcription from RNA polymerase II promoter, mitotic is_a: CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter [Term] id: CCO:P0000085 name: negative regulation of transcription from RNA polymerase III promoter, mitotic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators] synonym: "down regulation of transcription from RNA polymerase III promoter, mitotic" EXACT [] synonym: "down-regulation of transcription from RNA polymerase III promoter, mitotic" EXACT [] synonym: "downregulation of transcription from RNA polymerase III promoter, mitotic" EXACT [] synonym: "inhibition of transcription from RNA polymerase III promoter, mitotic" NARROW [] synonym: "mitotic repression of transcription from Pol III promoter" EXACT [] synonym: "negative regulation of transcription from Pol III promoter, mitotic" EXACT [] xref: GO:0007071 is_a: CCO:P0000082 ! negative regulation of transcription, mitotic is_a: CCO:P0000270 ! regulation of transcription from RNA polymerase III promoter, mitotic is_a: CCO:P0001128 ! negative regulation of transcription from RNA polymerase III promoter [Term] id: CCO:P0000086 name: positive regulation of transcription on exit from mitosis namespace: biological_process def: "Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:isa_complete, GOC:tb] synonym: "activation of transcription on exit from mitosis" NARROW [GOC:dph, GOC:tb] xref: GO:0007072 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0002625 ! positive regulation of transcription relationship: part_of CCO:P0000152 ! exit from mitosis [Term] id: CCO:P0000087 name: positive regulation of transcription on exit from mitosis, from RNA polymerase I promoter namespace: biological_process def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] synonym: "activation of transcription on exit from mitosis, from Pol I promoter" NARROW [GOC:dph, GOC:tb] synonym: "activation of transcription on exit from mitosis, from RNA polymerase I promoter" NARROW [] xref: GO:0007073 is_a: CCO:P0000086 ! positive regulation of transcription on exit from mitosis [Term] id: CCO:P0000088 name: positive regulation of transcription on exit from mitosis, from RNA polymerase II promoter namespace: biological_process def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] synonym: "activation of transcription on exit from mitosis, from Pol II promoter" NARROW [] synonym: "activation of transcription on exit from mitosis, from RNA polymerase II promoter" NARROW [] xref: GO:0007074 is_a: CCO:P0000086 ! positive regulation of transcription on exit from mitosis [Term] id: CCO:P0000089 name: positive regulation of transcription on exit from mitosis, from RNA polymerase III promoter namespace: biological_process def: "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] synonym: "activation of transcription on exit from mitosis, from Pol III promoter" NARROW [] synonym: "activation of transcription on exit from mitosis, from RNA polymerase III promoter" NARROW [GOC:dph, GOC:tb] xref: GO:0007075 is_a: CCO:P0000086 ! positive regulation of transcription on exit from mitosis [Term] id: CCO:P0000090 name: mitotic chromosome condensation namespace: biological_process def: "The cell cycle process whereby chromatin structure is compacted prior to mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194] xref: GO:0007076 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001399 ! AKAP8_HUMAN relationship: has_participant CCO:B0001400 ! O43832_HUMAN relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0001481 ! HSP1_HUMAN relationship: has_participant CCO:B0001482 ! PRM2_HUMAN relationship: has_participant CCO:B0001614 ! CNDD3_HUMAN relationship: has_participant CCO:B0001797 ! CND2_HUMAN relationship: has_participant CCO:B0001801 ! CND1_HUMAN relationship: has_participant CCO:B0001902 ! POLS_HUMAN relationship: has_participant CCO:B0001943 ! CNDG2_HUMAN relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: has_participant CCO:B0002092 ! CND3_HUMAN relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: has_participant CCO:B0002148 ! CHM1A_HUMAN relationship: has_participant CCO:B0002149 ! PRM3_HUMAN relationship: has_participant CCO:B0002168 ! SMC4_HUMAN relationship: has_participant CCO:B0041259 ! CNDH2_HUMAN relationship: has_participant CCO:B0043830 ! H1FNT_HUMAN relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000091 name: mitotic nuclear envelope disassembly namespace: biological_process def: "The cell cycle process whereby the controlled breakdown of the nuclear envelope during mitotic cell division occurs." [GOC:bf] synonym: "mitotic nuclear envelope breakdown" EXACT [] synonym: "mitotic nuclear envelope catabolism" EXACT [] synonym: "mitotic nuclear envelope degradation" EXACT [] xref: GO:0007077 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000092 name: lamin depolymerization namespace: biological_process def: "The cell cycle process whereby lamin is depolymerized." [GOC:jic] xref: GO:0007078 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000091 ! mitotic nuclear envelope disassembly [Term] id: CCO:P0000093 name: mitotic chromosome movement towards spindle pole namespace: biological_process def: "The cell cycle process whereby the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis." [GOC:ai] synonym: "chromosome migration to spindle pole during mitosis" EXACT [] synonym: "chromosome movement towards spindle pole during mitosis" EXACT [] synonym: "mitotic chromosome movement" BROAD [] synonym: "mitotic chromosome movement to spindle pole" EXACT [] synonym: "mitotic sister chromosome movement towards spindle pole" EXACT [] synonym: "sister chromosome movement towards spindle pole during mitosis" EXACT [] xref: GO:0007079 xref: GO:0007082 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0003079 ! chromosome movement towards spindle pole relationship: has_participant CCO:B0001715 ! CENPE_HUMAN relationship: has_participant CCO:B0001807 ! DLGP5_HUMAN relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000094 name: mitotic metaphase plate congression namespace: biological_process def: "The cell cycle process whereby chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis." [GOC:mah, ISBN:0815316194] xref: GO:0007080 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0003080 ! metaphase plate congression relationship: has_participant CCO:B0001715 ! CENPE_HUMAN relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000095 name: mitotic chromosome decondensation namespace: biological_process def: "The cell cycle process whereby chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells." [GOC:ai] xref: GO:0007083 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000096 name: mitotic nuclear envelope reassembly namespace: biological_process def: "The cell cycle process whereby the nuclear envelope reforms during mitotic cell division." [GOC:ai] xref: GO:0007084 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000097 name: vesicle fusion with nuclear membrane namespace: biological_process def: "The cell cycle process whereby the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus occurs." [GOC:jic] xref: GO:0007086 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000096 ! mitotic nuclear envelope reassembly [Term] id: CCO:P0000098 name: mitotic nuclear pore complex reassembly namespace: biological_process def: "The cell cycle process whereby nuclear pore complexes reform during mitotic cell division." [GOC:ai] xref: GO:0007087 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000096 ! mitotic nuclear envelope reassembly [Term] id: CCO:P0000099 name: regulation of mitosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators] xref: GO:0007088 is_a: CCO:P0000138 ! regulation of mitotic cell cycle is_a: CCO:P0000382 ! regulation of cell cycle process relationship: has_participant CCO:B0001357 ! ANM5_HUMAN relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0001755 ! PIN1_HUMAN relationship: has_participant CCO:B0001771 ! CD2L5_HUMAN relationship: has_participant CCO:B0002056 ! MPPH1_HUMAN relationship: has_participant CCO:B0002078 ! PMYT1_HUMAN relationship: regulates CCO:P0000081 ! mitosis [Term] id: CCO:P0000100 name: traversing start control point of mitotic cell cycle namespace: biological_process def: "Passage through a cell cycle control point late in G1 phase of the mitotic cell cycle just before entry into S phase; in most organisms studied, including budding yeast and animal cells, passage through start normally commits the cell to progressing through the entire cell cycle." [GOC:mah, ISBN:0815316194] synonym: "G1 checkpoint" RELATED [] xref: GO:0000081 xref: GO:0007089 is_a: CCO:P0000138 ! regulation of mitotic cell cycle relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001803 ! CDK10_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: part_of CCO:P0000011 ! G1 phase of mitotic cell cycle [Term] id: CCO:P0000101 name: regulation of S phase of mitotic cell cycle namespace: biological_process def: "A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle." [GOC:go_curators] xref: GO:0007090 is_a: CCO:P0000215 ! regulation of S phase relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0002123 ! ILKAP_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN relationship: part_of CCO:P0000138 ! regulation of mitotic cell cycle relationship: regulates CCO:P0000014 ! S phase of mitotic cell cycle [Term] id: CCO:P0000102 name: mitotic metaphase/anaphase transition namespace: biological_process def: "The cell cycle process whereby a cell progresses from metaphase to anaphase during mitosis, triggered by the destruction of mitotic cyclins." [PMID:10465783] xref: GO:0007091 xref: Reactome:211778 xref: Reactome:221543 xref: Reactome:230154 xref: Reactome:238183 xref: Reactome:68881 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001572 ! CDC27_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000103 name: activation of anaphase-promoting complex during mitotic cell cycle namespace: biological_process def: "Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the mitotic cell cycle." [GOC:dph, GOC:mah, GOC:tb, PMID:10871297] synonym: "activation of ubiquitin ligase activity of anaphase promoting complex during mitotic cell cycle" EXACT [] synonym: "activation of ubiquitin ligase activity of anaphase-promoting complex during mitotic cell cycle" EXACT [] synonym: "activation of ubiquitin ligase activity of APC during mitotic cell cycle" EXACT [] synonym: "anaphase promoting complex activation during mitotic cell cycle" EXACT [] synonym: "anaphase-promoting complex activation during mitotic cell cycle" EXACT [] synonym: "APC activation during mitotic cell cycle" EXACT [] synonym: "mitotic anaphase promoting complex activation" EXACT [] synonym: "mitotic anaphase promoting complex activator" NARROW [] synonym: "mitotic anaphase-promoting complex activation" EXACT [] synonym: "mitotic anaphase-promoting complex activator" NARROW [] synonym: "mitotic APC activation" EXACT [] synonym: "mitotic APC activator" NARROW [] xref: GO:0007092 xref: Reactome:162659 xref: Reactome:163010 xref: Reactome:204411 xref: Reactome:207643 xref: Reactome:213411 xref: Reactome:217136 xref: Reactome:223197 xref: Reactome:225891 xref: Reactome:231660 xref: Reactome:234574 xref: Reactome:239612 xref: Reactome:245838 xref: Reactome:250346 xref: Reactome:253161 xref: Reactome:256356 xref: Reactome:259780 xref: Reactome:265942 xref: Reactome:283716 is_a: CCO:P0000334 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: part_of CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition [Term] id: CCO:P0000104 name: mitotic cell cycle checkpoint namespace: biological_process def: "A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage." [GOC:mah, GOC:rn, PMID:12360190] synonym: "mitotic checkpoint" RELATED [] xref: GO:0007093 is_a: CCO:P0000006 ! cell cycle checkpoint is_a: CCO:P0000138 ! regulation of mitotic cell cycle relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001395 ! BUB1_HUMAN relationship: has_participant CCO:B0001396 ! BUB3_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001645 ! KNTC1_HUMAN relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0032821 ! ZWILC_HUMAN [Term] id: CCO:P0000105 name: mitotic cell cycle spindle assembly checkpoint namespace: biological_process def: "A signal transduction based surveillance mechanism that ensures the fidelity of cell division by preventing the premature advance of cells from metaphase to anaphase prior to the successful attachment of kinetochores to spindle microtubules (spindle assembly)." [GOC:rn, PMID:12360190] synonym: "Mad2-dependent checkpoint" NARROW [] synonym: "mitotic spindle checkpoint" RELATED [] xref: GO:0007094 xref: Reactome:212060 xref: Reactome:221823 xref: Reactome:230392 xref: Reactome:238432 xref: Reactome:244975 xref: Reactome:252583 xref: Reactome:255764 xref: Reactome:259160 xref: Reactome:262517 xref: Reactome:265345 xref: Reactome:268471 xref: Reactome:274195 xref: Reactome:280667 xref: Reactome:286686 xref: Reactome:69618 is_a: CCO:P0000104 ! mitotic cell cycle checkpoint is_a: CCO:P0000190 ! spindle checkpoint relationship: has_participant CCO:B0001395 ! BUB1_HUMAN relationship: has_participant CCO:B0001587 ! TTK_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN [Term] id: CCO:P0000106 name: mitotic cell cycle G2/M transition DNA damage checkpoint namespace: biological_process def: "A signal transduction-based surveillance mechanism that acts during a mitotic cell cycle to ensure accurate chromosome segregation by preventing entry into mitosis in the presence of damaged DNA." [GOC:mah, PMID:10856933, PMID:11406266] synonym: "mitotic G2 checkpoint" RELATED [] xref: GO:0007095 is_a: CCO:P0000185 ! G2/M transition DNA damage checkpoint relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN [Term] id: CCO:P0000107 name: regulation of exit from mitosis namespace: biological_process def: "Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity." [GOC:rn] xref: GO:0007096 is_a: CCO:P0000099 ! regulation of mitosis relationship: has_participant CCO:B0001341 ! A6NMP7_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001645 ! KNTC1_HUMAN relationship: has_participant CCO:B0001799 ! MD2BP_HUMAN relationship: has_participant CCO:B0001936 ! NPM2_HUMAN relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002060 ! NEB2_HUMAN relationship: has_participant CCO:B0002155 ! ANLN_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: regulates CCO:P0000152 ! exit from mitosis [Term] id: CCO:P0000108 name: centrosome cycle namespace: biological_process def: "The cell cycle process whereby centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle." [ISBN:0815316194] xref: GO:0007098 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0002114 ! Q9BYG9_HUMAN relationship: has_participant CCO:B0002211 ! TBE_HUMAN [Term] id: CCO:P0000109 name: centriole replication namespace: biological_process def: "The cell cycle process whereby a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type." [GOC:kva, ISBN:0815316194] synonym: "centriole duplication" EXACT [] xref: GO:0007099 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001961 ! CNTRB_HUMAN relationship: part_of CCO:P0000300 ! centrosome duplication [Term] id: CCO:P0000110 name: mitotic centrosome separation namespace: biological_process def: "Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [ISBN:0815316194] xref: GO:0007100 is_a: CCO:P0000301 ! centrosome separation relationship: has_participant CCO:B0001659 ! KIF11_HUMAN relationship: has_participant CCO:B0001731 ! CETN1_HUMAN [Term] id: CCO:P0000111 name: male meiosis centrosome cycle namespace: biological_process def: "Centrosome duplication and separation in the context of male meiosis." [GOC:mah] xref: GO:0007101 is_a: CCO:P0000108 ! centrosome cycle [Term] id: CCO:P0000112 name: spindle pole body duplication in nuclear envelope namespace: biological_process def: "Construction of a new spindle pole body adjacent to the existing spindle pole body in the nuclear envelope; usually occurs about the time of bud emergence." [ISBN:0879693649] synonym: "spindle pole body duplication (sensu Saccharomyces)" EXACT [] xref: GO:0007103 is_a: CCO:P0000164 ! spindle pole body duplication [Term] id: CCO:P0000113 name: cytokinesis after meiosis I namespace: biological_process def: "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells." [GOC:ai] xref: GO:0007110 is_a: CCO:P0000213 ! cytokinesis after meiosis [Term] id: CCO:P0000114 name: cytokinesis after meiosis II namespace: biological_process def: "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells." [GOC:ai] xref: GO:0007111 is_a: CCO:P0000213 ! cytokinesis after meiosis [Term] id: CCO:P0000115 name: male meiosis cytokinesis namespace: biological_process def: "A cell cycle process that occurs during male meiosis and results in the division of the cytoplasm of a cell to produce two daughter cells." [GOC:ai] xref: GO:0007112 is_a: CCO:P0000213 ! cytokinesis after meiosis [Term] id: CCO:P0000116 name: endomitotic cell cycle namespace: biological_process def: "A cell cycle in which chromosomes are replicated and sister chromatids separate, but neither spindle formation nor nuclear membrane breakdown, and nuclear division does not occur, resulting in an increased number of chromosomes in the cell." [GOC:expert_vm, http://www.onelook.com] synonym: "endomitosis" EXACT [] xref: GO:0007113 is_a: CCO:P0000066 ! cell cycle [Term] id: CCO:P0000117 name: meiosis namespace: biological_process def: "Progression through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations." [PMID:9334324] subset: goslim_yeast xref: GO:0007126 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001378 ! MSH4_HUMAN relationship: has_participant CCO:B0001381 ! MSH5_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001392 ! XRCC2_HUMAN relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001447 ! REC8_HUMAN relationship: has_participant CCO:B0001526 ! H2AX_HUMAN relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN relationship: has_participant CCO:B0001726 ! DMWD_HUMAN relationship: has_participant CCO:B0001753 ! TOP3A_HUMAN relationship: has_participant CCO:B0001784 ! DMC1_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001808 ! SYCP1_HUMAN relationship: has_participant CCO:B0001835 ! FBX43_HUMAN relationship: has_participant CCO:B0001882 ! UT14C_HUMAN relationship: has_participant CCO:B0001907 ! WBP2L_HUMAN relationship: has_participant CCO:B0001915 ! SYCE2_HUMAN relationship: has_participant CCO:B0001923 ! Q6ZNA8_HUMAN relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: has_participant CCO:B0001960 ! SYCE1_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0001972 ! BOLL_HUMAN relationship: has_participant CCO:B0001977 ! SMC1B_HUMAN relationship: has_participant CCO:B0001979 ! MNS1_HUMAN relationship: has_participant CCO:B0002007 ! CCNB3_HUMAN relationship: has_participant CCO:B0002012 ! RSPH1_HUMAN relationship: has_participant CCO:B0002016 ! RAD54_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN relationship: has_participant CCO:B0002106 ! SYCP2_HUMAN relationship: has_participant CCO:B0002207 ! DUS13_HUMAN relationship: has_participant CCO:B0002209 ! STAG3_HUMAN relationship: has_participant CCO:B0002240 ! EXO1_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0002246 ! OSGI2_HUMAN relationship: has_participant CCO:B0002255 ! RBM7_HUMAN relationship: has_participant CCO:B0002256 ! SPO11_HUMAN relationship: has_participant CCO:B0026255 ! KLDC3_HUMAN relationship: has_participant CCO:B0032571 ! HOP2_HUMAN relationship: has_participant CCO:B0032820 ! ZN318_HUMAN relationship: has_participant CCO:B0032873 ! MND1_HUMAN relationship: has_participant CCO:B0035937 ! S26A8_HUMAN relationship: has_participant CCO:B0039947 ! STRA8_HUMAN relationship: has_participant CCO:B0039948 ! ZFP42_HUMAN relationship: has_participant CCO:B0043818 ! MERP_HUMAN relationship: has_participant CCO:B0043831 ! H1FOO_HUMAN relationship: part_of CCO:P0000322 ! M phase of meiotic cell cycle [Term] id: CCO:P0000118 name: meiosis I namespace: biological_process def: "Progression through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." [PMID:9334324] xref: GO:0007127 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: part_of CCO:P0000117 ! meiosis [Term] id: CCO:P0000119 name: meiotic prophase I namespace: biological_process def: "Progression through prophase of meiosis I; divided into several stages." [GOC:mah] xref: GO:0007128 is_a: CCO:P0000319 ! prophase relationship: has_participant CCO:B0001413 ! RAD1_HUMAN relationship: has_participant CCO:B0001915 ! SYCE2_HUMAN relationship: has_participant CCO:B0001960 ! SYCE1_HUMAN relationship: has_participant CCO:B0001990 ! PIWL2_HUMAN relationship: has_participant CCO:B0002106 ! SYCP2_HUMAN relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000120 name: synapsis namespace: biological_process def: "The cell cycle process whereby the side by side pairing and physical juxtaposition of homologous chromosomes is created at the metaphase plate." [GOC:elh] synonym: "homologous chromosome pairing at meiosis" EXACT [] xref: GO:0007129 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001378 ! MSH4_HUMAN relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000121 name: synaptonemal complex assembly namespace: biological_process def: "The cell cycle process whereby the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "synaptonemal complex formation" EXACT [] xref: GO:0007130 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001808 ! SYCP1_HUMAN relationship: has_participant CCO:B0001900 ! Q5VXJ5_HUMAN relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: has_participant CCO:B0002018 ! SC65_HUMAN relationship: has_participant CCO:B0002106 ! SYCP2_HUMAN relationship: has_participant CCO:B0002209 ! STAG3_HUMAN relationship: part_of CCO:P0000120 ! synapsis [Term] id: CCO:P0000122 name: meiotic recombination namespace: biological_process def: "The cell cycle process whereby double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity." [PMID:2087779] synonym: "female meiotic recombination" NARROW [] synonym: "gene conversion with reciprocal crossover" EXACT [] xref: GO:0000021 xref: GO:0007131 xref: GO:0007145 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001337 ! A6NLT8_HUMAN relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001373 ! RA51B_HUMAN relationship: has_participant CCO:B0001378 ! MSH4_HUMAN relationship: has_participant CCO:B0001381 ! MSH5_HUMAN relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001434 ! RA51D_HUMAN relationship: has_participant CCO:B0001447 ! REC8_HUMAN relationship: has_participant CCO:B0001621 ! RAD52_HUMAN relationship: has_participant CCO:B0001638 ! DNLI3_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0001784 ! DMC1_HUMAN relationship: has_participant CCO:B0001808 ! SYCP1_HUMAN relationship: has_participant CCO:B0001886 ! Q5TCH6_HUMAN relationship: has_participant CCO:B0001887 ! Q5TCH7_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN relationship: has_participant CCO:B0002200 ! MLH3_HUMAN relationship: has_participant CCO:B0002256 ! SPO11_HUMAN relationship: has_participant CCO:B0002260 ! RA54B_HUMAN relationship: has_participant CCO:B0026255 ! KLDC3_HUMAN relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000123 name: meiotic metaphase I namespace: biological_process def: "Progression through metaphase of meiosis I; analogous to mitotic metaphase." [GOC:mah] xref: GO:0007132 is_a: CCO:P0000318 ! metaphase relationship: has_participant CCO:B0043838 ! FMN2_HUMAN relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000124 name: meiotic anaphase I namespace: biological_process def: "Progression through anaphase of meiosis I; analogous to mitotic anaphase." [GOC:mah] xref: GO:0007133 is_a: CCO:P0000317 ! anaphase relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000125 name: meiotic telophase I namespace: biological_process def: "Progression through telophase of meiosis I; analogous to mitotic telophase." [GOC:mah] xref: GO:0007134 is_a: CCO:P0000321 ! telophase relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000126 name: meiosis II namespace: biological_process def: "Progression through the second phase of meiosis, in which cells divide and separate the two chromatids in each chromosome." [ISBN:0198547684] xref: GO:0007135 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000117 ! meiosis [Term] id: CCO:P0000127 name: meiotic prophase II namespace: biological_process def: "Progression through prophase of meiosis II; analogous to mitotic prophase." [GOC:mah] xref: GO:0007136 is_a: CCO:P0000319 ! prophase relationship: has_participant CCO:B0001381 ! MSH5_HUMAN relationship: part_of CCO:P0000126 ! meiosis II [Term] id: CCO:P0000128 name: meiotic metaphase II namespace: biological_process def: "Progression through metaphase of meiosis II; analogous to mitotic metaphase." [GOC:mah] xref: GO:0007137 is_a: CCO:P0000318 ! metaphase relationship: part_of CCO:P0000126 ! meiosis II [Term] id: CCO:P0000129 name: meiotic anaphase II namespace: biological_process def: "Progression through anaphase of meiosis II; analogous to mitotic anaphase." [GOC:mah] xref: GO:0007138 is_a: CCO:P0000317 ! anaphase relationship: part_of CCO:P0000126 ! meiosis II [Term] id: CCO:P0000130 name: meiotic telophase II namespace: biological_process def: "Progression through telophase of meiosis II; analogous to mitotic telophase." [GOC:mah] xref: GO:0007139 is_a: CCO:P0000321 ! telophase relationship: part_of CCO:P0000126 ! meiosis II [Term] id: CCO:P0000131 name: male meiosis namespace: biological_process def: "Progression through the nuclear division phase of a meiotic cell cycle in the male germline." [GOC:mah] xref: GO:0007140 is_a: CCO:P0000117 ! meiosis relationship: has_participant CCO:B0001670 ! HSP72_HUMAN relationship: has_participant CCO:B0001959 ! TAF1L_HUMAN relationship: has_participant CCO:B0002157 ! CP26B_HUMAN relationship: has_participant CCO:B0002185 ! PIM2_HUMAN [Term] id: CCO:P0000132 name: male meiosis I namespace: biological_process def: "Progression through male meiosis I, the first meiotic division in the male germline." [GOC:mah] xref: GO:0007141 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: part_of CCO:P0000131 ! male meiosis [Term] id: CCO:P0000133 name: male meiosis II namespace: biological_process def: "Progression through male meiosis II, the second meiotic division in the male germline." [GOC:mah] xref: GO:0007142 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000131 ! male meiosis [Term] id: CCO:P0000134 name: female meiosis namespace: biological_process def: "Progression through the nuclear division phase of a meiotic cell cycle in the female germline." [GOC:ems, GOC:mah] comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaprodites such as those of C. elegans. See also the biological process term 'meiosis ; GO:0007126'. xref: GO:0007143 is_a: CCO:P0000117 ! meiosis relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001406 ! ADCY3_HUMAN [Term] id: CCO:P0000135 name: female meiosis I namespace: biological_process def: "The cell cycle process whereby the first meiotic division occurs in the female germline." [GOC:mah] xref: GO:0007144 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000134 ! female meiosis [Term] id: CCO:P0000136 name: meiotic recombination nodule assembly namespace: biological_process def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes." [GOC:jl, PMID:9334324] xref: GO:0007146 is_a: CCO:P0000045 ! meiotic DNA recombinase assembly [Term] id: CCO:P0000137 name: female meiosis II namespace: biological_process def: "The cell cycle process whereby the second meiotic division occurs in the female germline." [GOC:mah] xref: GO:0007147 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000134 ! female meiosis [Term] id: CCO:P0000138 name: regulation of mitotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "control of mitotic cell cycle progression" EXACT [] synonym: "mitotic cell cycle control" EXACT [] synonym: "mitotic cell cycle modulation" EXACT [] synonym: "mitotic cell cycle regulation" EXACT [] synonym: "mitotic cell cycle regulator" RELATED [] synonym: "modulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: GO:0007346 is_a: CCO:P0000346 ! regulation of cell cycle relationship: has_participant CCO:B0001435 ! CD123_HUMAN relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0001930 ! MAEA_HUMAN relationship: has_participant CCO:B0001964 ! AF1L2_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN relationship: has_participant CCO:B0043817 ! NGX6_HUMAN relationship: regulates CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000139 name: regulation of preblastoderm mitotic cell cycle namespace: biological_process def: "A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "control of preblastoderm mitotic cell cycle progression" EXACT [] synonym: "modulation of preblastoderm mitotic cell cycle progression" EXACT [] synonym: "preblastoderm mitotic cell cycle control" EXACT [] synonym: "preblastoderm mitotic cell cycle modulation" EXACT [] synonym: "preblastoderm mitotic cell cycle regulation" EXACT [] synonym: "preblastoderm mitotic cell cycle regulator" RELATED [] synonym: "regulation of preblastoderm mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through preblastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: GO:0007347 is_a: CCO:P0000145 ! regulation of mitotic cell cycle, embryonic relationship: regulates CCO:P0000223 ! preblastoderm mitotic cell cycle [Term] id: CCO:P0000140 name: regulation of syncytial blastoderm mitotic cell cycle namespace: biological_process def: "A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "control of syncytial blastoderm cell cycle progression" EXACT [] synonym: "modulation of syncytial blastoderm cell cycle progression" EXACT [] synonym: "regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "regulation of syncytial blastoderm cell cycle" EXACT [] synonym: "regulation of syncytial blastoderm cell cycle progression" EXACT [] synonym: "syncytial blastoderm cell cycle control" EXACT [] synonym: "syncytial blastoderm cell cycle modulation" EXACT [] synonym: "syncytial blastoderm cell cycle regulation" EXACT [] synonym: "syncytial blastoderm cell cycle regulator" RELATED [] xref: GO:0007348 is_a: CCO:P0000145 ! regulation of mitotic cell cycle, embryonic is_a: CCO:P0000159 ! cell cycle process relationship: regulates CCO:P0000224 ! syncytial blastoderm mitotic cell cycle [Term] id: CCO:P0000141 name: cyclin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of cyclins, proteins whose levels in a cell varies markedly during the cell cycle, and which play key roles in regulating cell cycle phase transitions." [GOC:mah, http://cancerweb.ncl.ac.uk/] synonym: "cyclin breakdown" EXACT [] synonym: "cyclin catabolism" EXACT [] synonym: "cyclin degradation" EXACT [] synonym: "degradation of cyclin" EXACT [] xref: GO:0008054 is_a: CCO:P0000346 ! regulation of cell cycle relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN [Term] id: CCO:P0000142 name: meiotic G2/MI transition namespace: biological_process def: "The cell cycle process whereby a cell progresses from meiotic prophase to metaphase I." [PMID:15088480] xref: GO:0008315 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000143 name: megasporogenesis namespace: biological_process def: "The process by which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus." [GOC:mtg_plant, GOC:tb] synonym: "megaspore development" EXACT [] synonym: "megaspore mother cell meiosis" EXACT [] synonym: "meiosis of the megasporocyte" EXACT [] synonym: "meiotic division of the megasporocyte" EXACT [] xref: GO:0009554 is_a: CCO:P0000362 ! plant-type spore development [Term] id: CCO:P0000144 name: microsporogenesis namespace: biological_process def: "The process by which the microsporocyte undergoes meiosis, giving rise to four haploid microspores." [GOC:mtg_plant, GOC:tb] synonym: "microspore development" EXACT systematic_synonym [] xref: GO:0009556 is_a: CCO:P0000362 ! plant-type spore development [Term] id: CCO:P0000145 name: regulation of mitotic cell cycle, embryonic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "control of embryonic mitotic cell cycle progression" EXACT [] synonym: "embryonic mitotic cell cycle control" EXACT [] synonym: "embryonic mitotic cell cycle modulation" EXACT [] synonym: "embryonic mitotic cell cycle regulation" EXACT [] synonym: "embryonic mitotic cell cycle regulator" RELATED [] synonym: "modulation of embryonic mitotic cell cycle progression" EXACT [] synonym: "regulation of embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "regulation of embryonic mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through embryonic mitotic cell cycle" EXACT [] xref: GO:0009794 is_a: CCO:P0000138 ! regulation of mitotic cell cycle relationship: regulates CCO:P0000241 ! mitotic cell cycle, embryonic [Term] id: CCO:P0000146 name: cell plate formation involved in plant-type cell wall biogenesis namespace: biological_process def: "The cell cycle process whereby the cell plate is formed at the equator of the spindle in the dividing cells during early telophase." [GOC:mtg_sensu, GOC:tb, ISBN:0879015322] synonym: "cell plate formation (sensu Magnoliophyta)" RELATED [] synonym: "cell plate formation involved in cellulose and pectin-containing cell wall biogenesis" EXACT [] xref: GO:0009920 is_a: CCO:P0000061 ! cell plate formation is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000147 name: anastral spindle assembly involved in male meiosis namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells." [GOC:tb, PMID:11973272] synonym: "male meiotic spindle assembly (sensu Viridiplantae)" EXACT [] xref: GO:0009971 is_a: CCO:P0000394 ! anastral spindle assembly relationship: part_of CCO:P0000131 ! male meiosis [Term] id: CCO:P0000148 name: zygote asymmetric cytokinesis in the embryo sac namespace: biological_process def: "The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm." [GOC:mtg_sensu, GOC:tb, ISBN:0865427429] synonym: "zygote asymmetric cytokinesis (sensu Magnoliophyta)" EXACT [] xref: GO:0010069 is_a: CCO:P0000212 ! cytokinesis during cell cycle is_a: CCO:P0000901 ! zygote asymmetric cell division [Term] id: CCO:P0000149 name: guard mother cell cytokinesis namespace: biological_process def: "The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells." [GOC:tb] synonym: "guard mother cell division" EXACT [] xref: GO:0010235 is_a: CCO:P0000055 ! cytokinesis by cell plate formation [Term] id: CCO:P0000150 name: regulation of G2/M transition of mitotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle." [PMID:17329565] xref: GO:0010389 is_a: CCO:P0000138 ! regulation of mitotic cell cycle is_a: CCO:P0000382 ! regulation of cell cycle process relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: regulates CCO:P0000016 ! G2/M transition of mitotic cell cycle [Term] id: CCO:P0000151 name: meristemoid mother cell division namespace: biological_process def: "The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC." [GOC:expert_db, GOC:tb] synonym: "meristemoid division" RELATED [] xref: GO:0010443 is_a: CCO:P0000055 ! cytokinesis by cell plate formation [Term] id: CCO:P0000152 name: exit from mitosis namespace: biological_process def: "The cell cycle process where a cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place." [GOC:dph, GOC:tb] xref: GO:0010458 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001933 ! CLAP1_HUMAN relationship: part_of CCO:P0000017 ! M phase of mitotic cell cycle [Term] id: CCO:P0000153 name: female meiosis chromosome segregation namespace: biological_process def: "The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai] xref: GO:0016321 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000237 ! meiotic chromosome segregation relationship: part_of CCO:P0000134 ! female meiosis [Term] id: CCO:P0000154 name: second mitotic wave during compound eye morphogenesis namespace: biological_process def: "A discrete cell cycle that occurs during the third instar eye imaginal disc after progression of the morphogenetic furrow. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia." [PMID:11257224] synonym: "second mitotic wave (sensu Endopterygota)" EXACT [] xref: GO:0016330 is_a: CCO:P0000066 ! cell cycle [Term] id: CCO:P0000155 name: meiotic chromosome movement towards spindle pole namespace: biological_process def: "The cell cycle process whereby the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis." [GOC:ai] synonym: "chromosome migration to spindle pole during meiosis" EXACT [] synonym: "chromosome movement towards spindle pole during meiosis" EXACT [] synonym: "meiotic chromosome movement" BROAD [] synonym: "meiotic chromosome movement to spindle pole" EXACT [] xref: GO:0016344 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0003079 ! chromosome movement towards spindle pole relationship: has_participant CCO:B0043838 ! FMN2_HUMAN relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000156 name: female meiotic chromosome movement towards spindle pole namespace: biological_process def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis." [GOC:ai] synonym: "chromosome movement towards spindle pole during female meiosis" EXACT [] synonym: "female meiotic chromosome movement" BROAD [] synonym: "female meiotic chromosome movement to spindle pole" EXACT [] xref: GO:0016345 is_a: CCO:P0000155 ! meiotic chromosome movement towards spindle pole relationship: part_of CCO:P0000153 ! female meiosis chromosome segregation [Term] id: CCO:P0000157 name: male meiotic chromosome movement towards spindle pole namespace: biological_process def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis." [GOC:ai] synonym: "chromosome movement towards spindle pole during male meiosis" EXACT [] synonym: "male meiotic chromosome movement" BROAD [] synonym: "male meiotic chromosome movement to spindle pole" EXACT [] xref: GO:0016346 is_a: CCO:P0000155 ! meiotic chromosome movement towards spindle pole relationship: part_of CCO:P0000075 ! male meiosis chromosome segregation [Term] id: CCO:P0000158 name: cell cycle arrest of committed forebrain neuronal progenitor cell namespace: biological_process def: "The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, GOC:tb, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021883 is_a: CCO:P0000067 ! cell cycle arrest [Term] id: CCO:P0000159 name: cell cycle process namespace: biological_process def: "A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:isa_complete] subset: gosubset_prok xref: GO:0022402 is_a: CCO:P0000887 ! cellular process relationship: part_of CCO:P0000066 ! cell cycle [Term] id: CCO:P0000160 name: cell cycle phase namespace: biological_process def: "A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events." [GOC:isa_complete] xref: GO:0022403 is_a: CCO:P0000159 ! cell cycle process [Term] id: CCO:P0000161 name: actin filament reorganization during cell cycle namespace: biological_process def: "The cell cycle process whereby rearrangement of the spatial distribution of actin filaments and associated proteins occurs." [GOC:mah] synonym: "actin filament reorganisation during cell cycle" EXACT [] xref: GO:0030037 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0002052 ! CEND2_HUMAN [Term] id: CCO:P0000162 name: regulation of mitotic metaphase/anaphase transition namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the onset of anaphase (chromosome movement) in the mitotic cell cycle." [GOC:mah] xref: GO:0030071 is_a: CCO:P0000099 ! regulation of mitosis relationship: has_participant CCO:B0001380 ! ZZEF1_HUMAN relationship: has_participant CCO:B0001875 ! HECD3_HUMAN relationship: has_participant CCO:B0001888 ! Q5TCY3_HUMAN relationship: has_participant CCO:B0001949 ! PARC_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0019420 ! Q53FN2_HUMAN relationship: regulates CCO:P0000102 ! mitotic metaphase/anaphase transition [Term] id: CCO:P0000163 name: mitotic spindle organization and biogenesis in nucleus namespace: biological_process def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the microtubule spindle in the nucleus during a mitotic cell cycle, as seen in Fungi." [GOC:mah] synonym: "mitotic spindle assembly (sensu Fungi)" NARROW [] synonym: "mitotic spindle assembly (sensu Saccharomyces)" NARROW [] synonym: "mitotic spindle organisation and biogenesis in nucleus" EXACT [] synonym: "mitotic spindle organization and biogenesis in cell nucleus" EXACT [] synonym: "spindle organization and biogenesis in nucleus during mitosis" EXACT [] xref: GO:0000071 xref: GO:0030472 is_a: CCO:P0000068 ! mitotic spindle organization and biogenesis [Term] id: CCO:P0000164 name: spindle pole body duplication namespace: biological_process def: "Construction of a new spindle pole body." [GOC:clt] synonym: "spindle pole body assembly" EXACT [] synonym: "spindle pole body biogenesis" EXACT [] synonym: "spindle pole body biosynthesis" EXACT [] synonym: "spindle pole body duplication (sensu Fungi)" EXACT [] synonym: "spindle pole body formation" EXACT [] synonym: "spindle pole body replication" EXACT [] xref: GO:0030474 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000302 ! spindle pole body organization and biogenesis [Term] id: CCO:P0000165 name: horsetail nuclear movement namespace: biological_process def: "The cell cycle process whereby oscillatory movement of the nucleus during meiotic prophase I occurs. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, which may facilitate synapsis necessary for efficient meiotic recombination; as observed in S. pombe." [PMID:16111942, PMID:9572142] synonym: "HNM" EXACT [] synonym: "horsetail movement" EXACT [] xref: GO:0030989 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000117 ! meiosis [Term] id: CCO:P0000166 name: cell cycle arrest in response to nitrogen starvation namespace: biological_process def: "The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen." [GOC:dph, GOC:tb, GOC:vw] xref: GO:0030996 is_a: CCO:P0000067 ! cell cycle arrest [Term] id: CCO:P0000167 name: regulation of centriole-centriole cohesion namespace: biological_process def: "Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker." [PMID:11076968] xref: GO:0030997 is_a: CCO:P0001703 ! regulation of microtubule-based process relationship: has_participant CCO:B0002099 ! CP250_HUMAN relationship: part_of CCO:P0000108 ! centrosome cycle [Term] id: CCO:P0000168 name: linear element formation namespace: biological_process def: "The cell cycle process whereby a proteinaceous scaffold, related to the synaptonemal complex, is formed in association with S. pombe chromosomes during meiotic prophase." [GOC:mah, Sanger:jb "Jurg Bahler"] xref: GO:0030999 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000120 ! synapsis [Term] id: CCO:P0000169 name: septation initiation signaling namespace: biological_process def: "The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the begining of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis." [GOC:mah, GOC:vw, PMID:16775007] synonym: "septation initiation network" EXACT [] synonym: "septation initiation signalling" EXACT [] synonym: "SIN" EXACT [] xref: GO:0031028 is_a: CCO:P0000107 ! regulation of exit from mitosis is_a: CCO:P0000199 ! regulation of contractile ring contraction involved in cytokinesis is_a: CCO:P0000782 ! Ras protein signal transduction relationship: part_of CCO:P0000454 ! barrier septum formation [Term] id: CCO:P0000170 name: regulation of septation initiation signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of septation initiation signaling." [GOC:mah] synonym: "regulation of septation initiation network" EXACT [] synonym: "regulation of septation initiation signalling" EXACT [] xref: GO:0031029 is_a: CCO:P0001734 ! regulation of cytokinetic process is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: regulates CCO:P0000169 ! septation initiation signaling [Term] id: CCO:P0000171 name: negative regulation of septation initiation signaling namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of septation initiation signaling." [GOC:mah] synonym: "down regulation of septation initiation signaling" EXACT [] synonym: "down-regulation of septation initiation signaling" EXACT [] synonym: "downregulation of septation initiation signaling" EXACT [] synonym: "inhibition of septation initiation signaling" NARROW [] synonym: "negative regulation of septation initiation network" EXACT [] synonym: "negative regulation of septation initiation signalling" EXACT [] xref: GO:0031030 is_a: CCO:P0000170 ! regulation of septation initiation signaling is_a: CCO:P0002700 ! negative regulation of Ras protein signal transduction relationship: negatively_regulates CCO:P0000169 ! septation initiation signaling [Term] id: CCO:P0000172 name: positive regulation of septation initiation signaling namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of septation initiation signaling." [GOC:mah] synonym: "activation of septation initiation signaling" NARROW [] synonym: "positive regulation of septation initiation network" EXACT [] synonym: "positive regulation of septation initiation signalling" EXACT [] synonym: "stimulation of septation initiation signaling" NARROW [] synonym: "up regulation of septation initiation signaling" EXACT [] synonym: "up-regulation of septation initiation signaling" EXACT [] synonym: "upregulation of septation initiation signaling" EXACT [] xref: GO:0031031 is_a: CCO:P0000170 ! regulation of septation initiation signaling is_a: CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: positively_regulates CCO:P0000169 ! septation initiation signaling [Term] id: CCO:P0000173 name: spindle pole body duplication in cytoplasm namespace: biological_process def: "Construction of a new spindle pole body adjacent to the existing spindle pole body exterior to the outer nuclear envelope." [GOC:clt] synonym: "spindle pole body duplication (sensu Schizosaccharomyces)" EXACT [] xref: GO:0031046 is_a: CCO:P0000164 ! spindle pole body duplication [Term] id: CCO:P0000174 name: sister chromatid biorientation namespace: biological_process def: "The cell cycle process whereby sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles." [PMID:15309047] synonym: "chromosome biorientation" EXACT [] synonym: "sister kinetochore biorientation" EXACT [] xref: GO:0031134 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0003081 ! attachment of spindle microtubules to chromosome relationship: part_of CCO:P0000094 ! mitotic metaphase plate congression [Term] id: CCO:P0000176 name: ascospore-type prospore-specific spindle pole body modification namespace: biological_process def: "Structural modification of the spindle pole body that takes place during the second meiotic division during ascospore formation; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP)." [GOC:mah, PMID:14702385] synonym: "forespore specific spindle pole body modification" EXACT [] synonym: "forespore-specific spindle pole body modification" EXACT [] synonym: "prospore specific spindle pole body modification" EXACT [] synonym: "sporulation specific spindle pole body modification " EXACT [] xref: GO:0031322 is_a: CCO:P0000302 ! spindle pole body organization and biogenesis relationship: part_of CCO:P0001403 ! ascospore-type prospore formation [Term] id: CCO:P0000177 name: positive regulation of exit from mitosis namespace: biological_process def: "Any processactivates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity)." [GOC:mah] synonym: "activation of exit from mitosis" NARROW [] synonym: "stimulation of exit from mitosis" NARROW [] synonym: "up regulation of exit from mitosis" EXACT [] synonym: "up-regulation of exit from mitosis" EXACT [] synonym: "upregulation of exit from mitosis" EXACT [] xref: GO:0031536 is_a: CCO:P0000107 ! regulation of exit from mitosis is_a: CCO:P0000251 ! positive regulation of mitosis relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0002022 ! NGN1_HUMAN relationship: positively_regulates CCO:P0000152 ! exit from mitosis [Term] id: CCO:P0000178 name: cytokinesis checkpoint namespace: biological_process def: "A cell cycle checkpoint that ensures the correct temporal ordering of nuclear division and cytokinesis; arrests the cell cycle in G2 upon perturbation of cytokinetic structures. In Schizosaccharomyces, the checkpoint monitors formation and integrity of medial actomyosin ring and septum." [GOC:mah, PMID:15647375] synonym: "contractile ring checkpoint" EXACT [] xref: GO:0031565 is_a: CCO:P0000006 ! cell cycle checkpoint [Term] id: CCO:P0000179 name: contractile ring maintenance involved in cytokinesis namespace: biological_process def: "The cell cycle process whereby the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures." [GOC:dph, GOC:tb, GOC:vw] synonym: "cytokinesis, contractile ring maintenance" EXACT [GOC:dph, GOC:tb] xref: GO:0031566 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000212 ! cytokinesis during cell cycle [Term] id: CCO:P0000180 name: cell size control checkpoint namespace: biological_process def: "Any cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size." [GOC:mah] xref: GO:0031567 is_a: CCO:P0000104 ! mitotic cell cycle checkpoint [Term] id: CCO:P0000181 name: G1/S transition size control checkpoint namespace: biological_process def: "A cell cycle checkpoint that blocks cell cycle progression from G1 to S phase until cells have reached a critical size." [GOC:mah] xref: GO:0031568 is_a: CCO:P0000180 ! cell size control checkpoint is_a: CCO:P0000188 ! G1/S transition checkpoint [Term] id: CCO:P0000182 name: G2/M transition size control checkpoint namespace: biological_process def: "A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase until cells have reached a critical size." [GOC:mah] xref: GO:0031569 is_a: CCO:P0000180 ! cell size control checkpoint is_a: CCO:P0000189 ! G2/M transition checkpoint [Term] id: CCO:P0000183 name: DNA integrity checkpoint namespace: biological_process def: "Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure." [GOC:mah, GOC:vw] xref: GO:0031570 is_a: CCO:P0000006 ! cell cycle checkpoint [Term] id: CCO:P0000184 name: G1 DNA damage checkpoint namespace: biological_process def: "A cell cycle checkpoint that arrests cell cycle progression G1 phase in response to DNA damage." [GOC:mah] xref: GO:0031571 is_a: CCO:P0000008 ! DNA damage checkpoint is_a: CCO:P0000188 ! G1/S transition checkpoint [Term] id: CCO:P0000185 name: G2/M transition DNA damage checkpoint namespace: biological_process def: "A cell cycle checkpoint that blocks cell cycle progression from G2 to M phase in response to DNA damage." [GOC:mah] xref: GO:0031572 is_a: CCO:P0000008 ! DNA damage checkpoint is_a: CCO:P0000189 ! G2/M transition checkpoint relationship: has_participant CCO:B0001909 ! RINT1_HUMAN relationship: has_participant CCO:B0001992 ! BRSK1_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:P0000186 name: intra-S DNA damage checkpoint namespace: biological_process def: "The slowing of DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progession." [GOC:vw] xref: GO:0031573 is_a: CCO:P0000008 ! DNA damage checkpoint relationship: has_participant CCO:B0001714 ! XPC_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN [Term] id: CCO:P0000187 name: S-M checkpoint namespace: biological_process def: "A cell cycle checkpoint which halts replication in response to nucleotide depletion." [GOC:vw] xref: GO:0031574 is_a: CCO:P0000008 ! DNA damage checkpoint is_a: CCO:P0000104 ! mitotic cell cycle checkpoint relationship: has_participant CCO:B0001758 ! ULA1_HUMAN [Term] id: CCO:P0000188 name: G1/S transition checkpoint namespace: biological_process def: "Any cell cycle checkpoint that blocks entry into S phase." [GOC:mah] xref: GO:0031575 is_a: CCO:P0000104 ! mitotic cell cycle checkpoint relationship: has_participant CCO:B0001419 ! HUS1_HUMAN relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001736 ! DLG1_HUMAN [Term] id: CCO:P0000189 name: G2/M transition checkpoint namespace: biological_process def: "Any cell cycle checkpoint that blocks entry into M phase." [GOC:mah] synonym: "G2/M checkpoint" EXACT [] xref: GO:0031576 is_a: CCO:P0000104 ! mitotic cell cycle checkpoint [Term] id: CCO:P0000190 name: spindle checkpoint namespace: biological_process def: "A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle." [GOC:mah, PMID:15897186] synonym: "SAC" BROAD [] synonym: "spindle assembly checkpoint" EXACT [] xref: GO:0031577 is_a: CCO:P0000006 ! cell cycle checkpoint relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN [Term] id: CCO:P0000191 name: mitotic cell cycle spindle orientation checkpoint namespace: biological_process def: "A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. The result is a cell cycle delay, usually in mitosis, until errors are corrected." [GOC:clt, PMID:14616062] synonym: "SOC" EXACT [] synonym: "spindle position checkpoint" EXACT [] synonym: "SPOC" EXACT [] xref: GO:0031578 is_a: CCO:P0000104 ! mitotic cell cycle checkpoint is_a: CCO:P0000190 ! spindle checkpoint [Term] id: CCO:P0000192 name: homologous chromosome orientation during meiosis namespace: biological_process def: "The cell cycle process whereby the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I." [PMID:15062096] synonym: "homologous chromosome orientation during meiosis I" EXACT [] xref: GO:0031619 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000231 ! meiotic metaphase I plate congression [Term] id: CCO:P0000193 name: G1/S-specific regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah] xref: GO:0031657 is_a: CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: part_of CCO:P0000012 ! G1/S transition of mitotic cell cycle [Term] id: CCO:P0000194 name: G1/S-specific negative regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah] synonym: "G1/S-specific down regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G1/S-specific down-regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G1/S-specific downregulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G1/S-specific inhibition of cyclin-dependent protein kinase activity" NARROW [] xref: GO:0031658 is_a: CCO:P0000193 ! G1/S-specific regulation of cyclin-dependent protein kinase activity is_a: CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity [Term] id: CCO:P0000195 name: G1/S-specific positive regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of CDK activity during the G1/S transition of the cell cycle." [GOC:mah] synonym: "G1/S-specific activation of cyclin-dependent protein kinase activity" NARROW [] synonym: "G1/S-specific stimulation of cyclin-dependent protein kinase activity" NARROW [] synonym: "G1/S-specific up regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G1/S-specific up-regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G1/S-specific upregulation of cyclin-dependent protein kinase activity" EXACT [] xref: GO:0031659 is_a: CCO:P0000193 ! G1/S-specific regulation of cyclin-dependent protein kinase activity is_a: CCO:P0000243 ! positive regulation of cyclin-dependent protein kinase activity [Term] id: CCO:P0000196 name: G2/M-specific regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah] xref: GO:0031660 is_a: CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity relationship: part_of CCO:P0000016 ! G2/M transition of mitotic cell cycle [Term] id: CCO:P0000197 name: G2/M-specific negative regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah] synonym: "G2/M-specific down regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G2/M-specific down-regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G2/M-specific downregulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G2/M-specific inhibition of cyclin-dependent protein kinase activity" NARROW [] xref: GO:0031661 is_a: CCO:P0000196 ! G2/M-specific regulation of cyclin-dependent protein kinase activity is_a: CCO:P0000242 ! negative regulation of cyclin-dependent protein kinase activity [Term] id: CCO:P0000198 name: G2/M-specific positive regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of CDK activity during the G2/M transition of the cell cycle." [GOC:mah] synonym: "G2/M-specific activation of cyclin-dependent protein kinase activity" NARROW [] synonym: "G2/M-specific stimulation of cyclin-dependent protein kinase activity" NARROW [] synonym: "G2/M-specific up regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G2/M-specific up-regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "G2/M-specific upregulation of cyclin-dependent protein kinase activity" EXACT [] xref: GO:0031662 is_a: CCO:P0000196 ! G2/M-specific regulation of cyclin-dependent protein kinase activity is_a: CCO:P0000243 ! positive regulation of cyclin-dependent protein kinase activity [Term] id: CCO:P0000199 name: regulation of contractile ring contraction involved in cytokinesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis." [GOC:dph, GOC:mah, GOC:tb] xref: GO:0031991 is_a: CCO:P0000346 ! regulation of cell cycle is_a: CCO:P0001625 ! regulation of cytokinesis is_a: CCO:P0001637 ! cytokinetic process is_a: CCO:P0001734 ! regulation of cytokinetic process relationship: regulates CCO:P0000060 ! contractile ring contraction involved in cytokinesis [Term] id: CCO:P0000200 name: attachment of telomeres to spindle pole body namespace: biological_process def: "The cell cycle process whereby physical connections are formed between telomeres and the spindle pole body, facilitating bouquet formation." [PMID:16615890] xref: GO:0032121 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000238 ! meiotic telomere clustering [Term] id: CCO:P0000201 name: cellular bud neck septin ring organization namespace: biological_process def: "Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck." [GOC:mah] xref: GO:0032186 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000212 ! cytokinesis during cell cycle relationship: part_of CCO:P0000696 ! cytokinesis, site selection [Term] id: CCO:P0000202 name: establishment of contractile ring localization namespace: biological_process def: "The process by which a contractile ring is assembled in a specific location." [GOC:mah] xref: GO:0032188 is_a: CCO:P0001544 ! contractile ring localization relationship: part_of CCO:P0000059 ! cytokinesis, contractile ring formation relationship: part_of CCO:P0000696 ! cytokinesis, site selection [Term] id: CCO:P0000203 name: maintenance of contractile ring localization namespace: biological_process def: "Any process by which a contractile ring is maintained in a location and prevented from moving elsewhere." [GOC:mah] synonym: "cytokinetic ring anchoring" RELATED [] xref: GO:0032189 is_a: CCO:P0001544 ! contractile ring localization relationship: part_of CCO:P0000179 ! contractile ring maintenance involved in cytokinesis [Term] id: CCO:P0000204 name: distributive segregation namespace: biological_process def: "The cell cycle process whereby genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a \"backup\" mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally." [GOC:expert_rsh, GOC:ma, GOC:sart] xref: GO:0032837 is_a: CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000205 name: regulation of spindle elongation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the cell cycle process whereby the distance is lengthened between poles of the spindle." [GOC:mah] xref: GO:0032887 is_a: CCO:P0000382 ! regulation of cell cycle process is_a: CCO:P0001703 ! regulation of microtubule-based process relationship: regulates CCO:P0000293 ! spindle elongation [Term] id: CCO:P0000206 name: regulation of mitotic spindle elongation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the cell cycle process whereby the distance is lengthened between poles of the mitotic spindle." [GOC:mah] xref: GO:0032888 is_a: CCO:P0000205 ! regulation of spindle elongation relationship: regulates CCO:P0000001 ! mitotic spindle elongation [Term] id: CCO:P0000207 name: dipyrromethane cofactor binding namespace: biological_process def: "Interacting selectively with the dipyrromethane cofactor, 3,8-bis(carboxymethyl)-9-methyl-5,10-dihydrodipyrrin-2,7-dipropionic acid." [ChEBI:30410, GOC:mah] xref: GO:0033035 is_a: CCO:P0000169 ! septation initiation signaling [Term] id: CCO:P0000208 name: regulation of sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation." [GOC:mah] xref: GO:0033045 is_a: CCO:P0000382 ! regulation of cell cycle process is_a: CCO:P0001766 ! regulation of chromosome organization and biogenesis relationship: regulates CCO:P0000054 ! sister chromatid segregation [Term] id: CCO:P0000209 name: negative regulation of sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." [GOC:mah] xref: GO:0033046 is_a: CCO:P0000208 ! regulation of sister chromatid segregation is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis relationship: negatively_regulates CCO:P0000054 ! sister chromatid segregation [Term] id: CCO:P0000210 name: regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] xref: GO:0033047 is_a: CCO:P0000208 ! regulation of sister chromatid segregation relationship: regulates CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000211 name: negative regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] xref: GO:0033048 is_a: CCO:P0000209 ! negative regulation of sister chromatid segregation is_a: CCO:P0000210 ! regulation of mitotic sister chromatid segregation relationship: negatively_regulates CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000212 name: cytokinesis during cell cycle namespace: biological_process def: "Cytokinesis that occurs in the context of cell cycle progression and result in the division of the cytoplasm of a cell and its separation into two daughter cells." [GOC:mah] xref: GO:0033205 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000453 ! cytokinesis relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0043836 ! BBS4_HUMAN [Term] id: CCO:P0000213 name: cytokinesis after meiosis namespace: biological_process def: "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells." [GOC:mah] xref: GO:0033206 is_a: CCO:P0000212 ! cytokinesis during cell cycle [Term] id: CCO:P0000214 name: DNA replication during S phase namespace: biological_process def: "The process whereby new strands of genomic DNA are synthesized, using parental DNA as a template for DNA-dependent DNA polymerases, during progression through S phase of the cell cycle." [GOC:mah] xref: GO:0033260 is_a: CCO:P0000629 ! DNA-dependent DNA replication relationship: part_of CCO:P0000315 ! S phase [Term] id: CCO:P0000215 name: regulation of S phase namespace: biological_process def: "A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of progression through S phase" EXACT [GOC:dph, GOC:tb] xref: GO:0033261 xref: MetaCyc:PWY-5043 xref: MetaCyc:SALVADEHYPOX-PWY xref: MetaCyc:SALVPURINE2-PWY is_a: CCO:P0000346 ! regulation of cell cycle is_a: CCO:P0000382 ! regulation of cell cycle process relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: has_participant CCO:B0002235 ! TIM_HUMAN relationship: regulates CCO:P0000315 ! S phase [Term] id: CCO:P0000216 name: regulation of DNA replication during S phase namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA replication during progression through S phase of the cell cycle." [GOC:mah] xref: GO:0033262 is_a: CCO:P0000215 ! regulation of S phase is_a: CCO:P0000639 ! regulation of DNA replication relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: regulates CCO:P0000214 ! DNA replication during S phase [Term] id: CCO:P0000217 name: abortive mitotic cell cycle namespace: biological_process def: "A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy." [GOC:mah, PMID:9573008] comment: Note that this term should be used only for abortive mitotic events that occur normally, e.g. during megakaryocyte differentiation; it should not be used for incomplete mitosis resulting from mutation or other abnormal occurrences. synonym: "abortive mitosis" RELATED [] xref: GO:0033277 is_a: CCO:P0000066 ! cell cycle [Term] id: CCO:P0000218 name: cell cycle comprising mitosis without cytokinesis namespace: biological_process def: "A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N)." [GOC:expert_vm, GOC:mah] comment: Note that this term should be used for naturally occurring instances of mitosis without cytokinesis, e.g. in the tapetum of flowers and in a number of lower eukaryotes; it should not be used for abnormal events such as may occur in cancers. xref: GO:0033301 is_a: CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000219 name: meiotic cell cycle checkpoint namespace: biological_process def: "A signal transduction-based surveillance mechanism that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage." [GOC:mah] xref: GO:0033313 is_a: CCO:P0000006 ! cell cycle checkpoint [Term] id: CCO:P0000220 name: mitotic cell cycle DNA replication checkpoint namespace: biological_process def: "A signal transduction based surveillance mechanism that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome." [GOC:mah] xref: GO:0033314 is_a: CCO:P0000007 ! DNA replication checkpoint is_a: CCO:P0000104 ! mitotic cell cycle checkpoint [Term] id: CCO:P0000221 name: meiotic cell cycle DNA replication checkpoint namespace: biological_process def: "A signal transduction based surveillance mechanism that acts during a meiotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the haploid genome." [GOC:mah] xref: GO:0033315 is_a: CCO:P0000007 ! DNA replication checkpoint is_a: CCO:P0000219 ! meiotic cell cycle checkpoint [Term] id: CCO:P0000222 name: meiotic spindle checkpoint namespace: biological_process def: "A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle." [GOC:mah] xref: GO:0033316 is_a: CCO:P0000190 ! spindle checkpoint [Term] id: CCO:P0000223 name: preblastoderm mitotic cell cycle namespace: biological_process def: "The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis." [ISBN:0879694238] xref: GO:0035185 is_a: CCO:P0000218 ! cell cycle comprising mitosis without cytokinesis is_a: CCO:P0000241 ! mitotic cell cycle, embryonic [Term] id: CCO:P0000224 name: syncytial blastoderm mitotic cell cycle namespace: biological_process def: "Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively." [ISBN:0879694238] xref: GO:0035186 is_a: CCO:P0000218 ! cell cycle comprising mitosis without cytokinesis is_a: CCO:P0000241 ! mitotic cell cycle, embryonic [Term] id: CCO:P0000225 name: establishment of mitotic spindle localization namespace: biological_process def: "The cell cycle process whereby the directed movement of the mitotic spindle to a specific location in the cell occurs." [GOC:ai] synonym: "mitotic spindle positioning" EXACT [] synonym: "mitotic spindle positioning (sensu Fungi)" NARROW [] synonym: "mitotic spindle positioning (sensu Saccharomyces)" NARROW [] synonym: "mitotic spindle positioning and orientation (sensu Saccharomyces)" NARROW [] synonym: "mitotic spindle positioning or orientation" EXACT [] synonym: "mitotic spindle positioning or orientation (sensu Fungi)" NARROW [] synonym: "spindle positioning during mitosis" EXACT [] xref: GO:0018986 xref: GO:0030605 xref: GO:0030606 xref: GO:0030608 xref: GO:0030610 xref: GO:0040001 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001787 ! ESPL1_HUMAN relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: part_of CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000226 name: regulation of meiosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of meiosis, the process by which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma] xref: GO:0040020 is_a: CCO:P0000339 ! regulation of meiotic cell cycle is_a: CCO:P0000382 ! regulation of cell cycle process relationship: has_participant CCO:B0001563 ! CALR_HUMAN relationship: regulates CCO:P0000117 ! meiosis [Term] id: CCO:P0000227 name: polar body extrusion after meiotic divisions namespace: biological_process def: "The cell cycle process whereby two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes." [GOC:ems, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] xref: GO:0040038 is_a: CCO:P0000213 ! cytokinesis after meiosis relationship: has_participant CCO:B0043838 ! FMN2_HUMAN relationship: part_of CCO:P0000134 ! female meiosis [Term] id: CCO:P0000228 name: meiotic DNA double-strand break formation namespace: biological_process def: "The cell cycle process whereby double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination." [GOC:elh, GOC:jl, PMID:11529427] xref: GO:0042138 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000063 ! meiotic gene conversion relationship: part_of CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000229 name: early meiotic recombination nodule assembly namespace: biological_process def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene." [GOC:jl, PMID:9334324] xref: GO:0042139 is_a: CCO:P0000136 ! meiotic recombination nodule assembly [Term] id: CCO:P0000230 name: late meiotic recombination nodule assembly namespace: biological_process def: "During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over." [GOC:jl, PMID:9334324] xref: GO:0042140 is_a: CCO:P0000136 ! meiotic recombination nodule assembly [Term] id: CCO:P0000231 name: meiotic metaphase I plate congression namespace: biological_process def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I." [GOC:cab1, PMID:10809666] xref: GO:0043060 is_a: CCO:P0000308 ! meiotic metaphase plate congression relationship: part_of CCO:P0000239 ! homologous chromosome segregation [Term] id: CCO:P0000232 name: meiotic metaphase II plate congression namespace: biological_process def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II." [GOC:cab1, PMID:10809666] xref: GO:0043061 is_a: CCO:P0000308 ! meiotic metaphase plate congression relationship: part_of CCO:P0000240 ! meiotic sister chromatid segregation [Term] id: CCO:P0000233 name: meiotic spindle stabilization namespace: biological_process def: "The cell cycle process whereby spindle integrity is maintained during M phase of meiosis." [GOC:go_curators] xref: GO:0043147 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000391 ! spindle stabilization relationship: part_of CCO:P0000030 ! meiotic spindle organization and biogenesis [Term] id: CCO:P0000234 name: mitotic spindle stabilization namespace: biological_process def: "The cell cycle process whereby spindle integrity is maintained during M phase of mitosis." [GOC:go_curators] xref: GO:0043148 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000391 ! spindle stabilization relationship: has_participant CCO:B0025212 ! SBDS_HUMAN relationship: part_of CCO:P0000068 ! mitotic spindle organization and biogenesis [Term] id: CCO:P0000235 name: G0 to G1 transition namespace: biological_process def: "The transition from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression." [ISBN:0716731363] xref: GO:0045023 is_a: CCO:P0000041 ! re-entry into mitotic cell cycle relationship: has_participant CCO:B0001366 ! MDM4_HUMAN [Term] id: CCO:P0000236 name: negative regulation of meiotic recombination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of recombination during meiosis." [GOC:ai] synonym: "down regulation of meiotic recombination" EXACT [] synonym: "down-regulation of meiotic recombination" EXACT [] synonym: "downregulation of meiotic recombination" EXACT [] synonym: "inhibition of meiotic recombination" NARROW [] synonym: "suppression of meiotic recombination" EXACT [] xref: GO:0045128 is_a: CCO:P0000248 ! negative regulation of meiosis is_a: CCO:P0000381 ! regulation of meiotic recombination is_a: CCO:P0002607 ! negative regulation of DNA recombination relationship: negatively_regulates CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000237 name: meiotic chromosome segregation namespace: biological_process def: "The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle." [GOC:ai] xref: GO:0045132 is_a: CCO:P0000695 ! chromosome segregation relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: part_of CCO:P0000117 ! meiosis [Term] id: CCO:P0000238 name: meiotic telomere clustering namespace: biological_process def: "The cell cycle process whereby the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in homologous chromosome pairing and therefore progression through meiosis." [GOC:vw, PMID:10690419] synonym: "bouquet biosynthesis" NARROW [] synonym: "bouquet formation" NARROW [] xref: GO:0045141 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000117 ! meiosis [Term] id: CCO:P0000239 name: homologous chromosome segregation namespace: biological_process def: "The cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, ISBN:0815316194] synonym: "meiosis I, chromosome segregation" EXACT [] xref: GO:0007061 xref: GO:0045143 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000118 ! meiosis I relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000240 name: meiotic sister chromatid segregation namespace: biological_process def: "The cell cycle process whereby sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194] synonym: "meiosis II, chromosome segregation" EXACT [] xref: GO:0045144 is_a: CCO:P0000054 ! sister chromatid segregation relationship: part_of CCO:P0000126 ! meiosis II relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000241 name: mitotic cell cycle, embryonic namespace: biological_process def: "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo." [GOC:go_curators] xref: GO:0045448 is_a: CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000242 name: negative regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of CDK activity." [GOC:go_curators] synonym: "CDK inhibitor" RELATED [] synonym: "cyclin-dependent kinase inhibitor" RELATED [] synonym: "down regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "down-regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "downregulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "inhibition of cyclin-dependent protein kinase activity" NARROW [] synonym: "negative regulation of CDK activity" EXACT [] xref: GO:0045736 is_a: CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity is_a: CCO:P0000246 ! negative regulation of cell cycle relationship: has_participant CCO:B0001445 ! HEXI1_HUMAN relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0002049 ! HEXI2_HUMAN relationship: has_participant CCO:B0002062 ! CK5P1_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN [Term] id: CCO:P0000243 name: positive regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of CDK activity." [GOC:go_curators] synonym: "activation of cyclin-dependent protein kinase activity" NARROW [] synonym: "positive regulation of CDK activity" EXACT [] synonym: "stimulation of cyclin-dependent protein kinase activity" NARROW [] synonym: "up regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "up-regulation of cyclin-dependent protein kinase activity" EXACT [] synonym: "upregulation of cyclin-dependent protein kinase activity" EXACT [] xref: GO:0045737 is_a: CCO:P0000010 ! regulation of cyclin-dependent protein kinase activity is_a: CCO:P0000247 ! positive regulation of cell cycle relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001573 ! CCND2_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN [Term] id: CCO:P0000244 name: negative regulation of S phase of mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators] synonym: "down regulation of S phase of mitotic cell cycle" EXACT [] synonym: "down-regulation of S phase of mitotic cell cycle" EXACT [] synonym: "downregulation of S phase of mitotic cell cycle" EXACT [] synonym: "inhibition of S phase of mitotic cell cycle" NARROW [] xref: GO:0045749 is_a: CCO:P0000101 ! regulation of S phase of mitotic cell cycle is_a: CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001672 ! GAS1_HUMAN relationship: has_participant CCO:B0001998 ! Q8TEY4_HUMAN relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0002148 ! CHM1A_HUMAN relationship: has_participant CCO:B0002267 ! MYO16_HUMAN relationship: has_participant CCO:B0025035 ! Q7Z324_HUMAN relationship: negatively_regulates CCO:P0000014 ! S phase of mitotic cell cycle [Term] id: CCO:P0000245 name: positive regulation of S phase of mitotic cell cycle namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity." [GOC:go_curators] synonym: "activation of S phase of mitotic cell cycle" NARROW [] synonym: "stimulation of S phase of mitotic cell cycle" NARROW [] synonym: "up regulation of S phase of mitotic cell cycle" EXACT [] synonym: "up-regulation of S phase of mitotic cell cycle" EXACT [] synonym: "upregulation of S phase of mitotic cell cycle" EXACT [] xref: GO:0045750 is_a: CCO:P0000101 ! regulation of S phase of mitotic cell cycle is_a: CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: positively_regulates CCO:P0000014 ! S phase of mitotic cell cycle [Term] id: CCO:P0000246 name: negative regulation of cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through cell cycle" EXACT [] synonym: "down-regulation of progression through cell cycle" EXACT [] synonym: "downregulation of progression through cell cycle" EXACT [] synonym: "inhibition of progression through cell cycle" NARROW [] synonym: "negative regulation of cell cycle progression" EXACT [] synonym: "negative regulation of progression through cell cycle" EXACT [] xref: GO:0045786 is_a: CCO:P0000346 ! regulation of cell cycle is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0001349 ! BIN1_HUMAN relationship: has_participant CCO:B0001350 ! LHR2A_HUMAN relationship: has_participant CCO:B0001355 ! CDKA1_HUMAN relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0001371 ! LX15B_HUMAN relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001383 ! KLK10_HUMAN relationship: has_participant CCO:B0001385 ! LEU1_HUMAN relationship: has_participant CCO:B0001386 ! LEU2_HUMAN relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0001409 ! DBC1_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001416 ! TRI13_HUMAN relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0001438 ! TUSC2_HUMAN relationship: has_participant CCO:B0001444 ! SASH1_HUMAN relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001455 ! RECK_HUMAN relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001496 ! FUMH_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001510 ! IRF1_HUMAN relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0001516 ! BMP4_HUMAN relationship: has_participant CCO:B0001523 ! PGDH_HUMAN relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0001531 ! BMP7_HUMAN relationship: has_participant CCO:B0001532 ! PACA_HUMAN relationship: has_participant CCO:B0001536 ! WT1_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0001549 ! CRCM_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001567 ! RBL1_HUMAN relationship: has_participant CCO:B0001568 ! EPHB2_HUMAN relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0001607 ! NBL1_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001619 ! DCC_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0001636 ! FHIT_HUMAN relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001646 ! RASF2_HUMAN relationship: has_participant CCO:B0001660 ! RBM5_HUMAN relationship: has_participant CCO:B0001666 ! HRSL3_HUMAN relationship: has_participant CCO:B0001668 ! PMS1_HUMAN relationship: has_participant CCO:B0001669 ! PMS2_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001692 ! RHOB_HUMAN relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0001725 ! RBL2_HUMAN relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0001765 ! PTC1_HUMAN relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0001783 ! HIC1_HUMAN relationship: has_participant CCO:B0001789 ! KANK1_HUMAN relationship: has_participant CCO:B0001818 ! EXT1_HUMAN relationship: has_participant CCO:B0001831 ! Q3LRW5_HUMAN relationship: has_participant CCO:B0001832 ! TBRG1_HUMAN relationship: has_participant CCO:B0001836 ! PDCD4_HUMAN relationship: has_participant CCO:B0001838 ! PKHO1_HUMAN relationship: has_participant CCO:B0001894 ! LIN9_HUMAN relationship: has_participant CCO:B0001899 ! DAB2P_HUMAN relationship: has_participant CCO:B0001904 ! KCD11_HUMAN relationship: has_participant CCO:B0001911 ! CDC73_HUMAN relationship: has_participant CCO:B0001954 ! XRN1_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0001971 ! BANP_HUMAN relationship: has_participant CCO:B0001978 ! PPC1B_HUMAN relationship: has_participant CCO:B0001981 ! FLCN_HUMAN relationship: has_participant CCO:B0001983 ! CADM4_HUMAN relationship: has_participant CCO:B0001995 ! RBCC1_HUMAN relationship: has_participant CCO:B0002000 ! TUSC4_HUMAN relationship: has_participant CCO:B0002008 ! RASF5_HUMAN relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0002026 ! NAT6_HUMAN relationship: has_participant CCO:B0002028 ! EXT2_HUMAN relationship: has_participant CCO:B0002033 ! PINX1_HUMAN relationship: has_participant CCO:B0002039 ! SIPA1_HUMAN relationship: has_participant CCO:B0002046 ! ASPP1_HUMAN relationship: has_participant CCO:B0002094 ! LZTS2_HUMAN relationship: has_participant CCO:B0002098 ! HTAI2_HUMAN relationship: has_participant CCO:B0002110 ! CADM1_HUMAN relationship: has_participant CCO:B0002117 ! DPH1_HUMAN relationship: has_participant CCO:B0002123 ! ILKAP_HUMAN relationship: has_participant CCO:B0002128 ! TSYL2_HUMAN relationship: has_participant CCO:B0002129 ! RASF4_HUMAN relationship: has_participant CCO:B0002131 ! PININ_HUMAN relationship: has_participant CCO:B0002147 ! BRMS1_HUMAN relationship: has_participant CCO:B0002153 ! CYLD_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0002181 ! WWOX_HUMAN relationship: has_participant CCO:B0002188 ! RHG20_HUMAN relationship: has_participant CCO:B0002189 ! DEC1_HUMAN relationship: has_participant CCO:B0002197 ! DMBT1_HUMAN relationship: has_participant CCO:B0002201 ! SEPT9_HUMAN relationship: has_participant CCO:B0002205 ! MUTYH_HUMAN relationship: has_participant CCO:B0002217 ! ING1_HUMAN relationship: has_participant CCO:B0002224 ! MTUS1_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0002234 ! ING4_HUMAN relationship: has_participant CCO:B0002247 ! DLEC1_HUMAN relationship: has_participant CCO:B0002248 ! LZTS1_HUMAN relationship: has_participant CCO:B0002253 ! STA13_HUMAN relationship: has_participant CCO:B0022296 ! Q3LRW1_HUMAN relationship: has_participant CCO:B0022298 ! Q3LRW4_HUMAN relationship: has_participant CCO:B0022308 ! Q1MSW9_HUMAN relationship: has_participant CCO:B0022312 ! Q3LRW3_HUMAN relationship: has_participant CCO:B0026249 ! ZMY11_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0039945 ! CRBL2_HUMAN relationship: has_participant CCO:B0041254 ! PTOR1_HUMAN relationship: has_participant CCO:B0041258 ! XAF1_HUMAN relationship: has_participant CCO:B0041264 ! PRDBP_HUMAN relationship: has_participant CCO:B0041267 ! DMTF1_HUMAN relationship: has_participant CCO:B0043816 ! ZBT7C_HUMAN relationship: has_participant CCO:B0043820 ! AIM2_HUMAN relationship: has_participant CCO:B0043828 ! IFIX_HUMAN relationship: has_participant CCO:B0043833 ! SC5A8_HUMAN relationship: has_participant CCO:B0043837 ! ST20_HUMAN relationship: negatively_regulates CCO:P0000066 ! cell cycle [Term] id: CCO:P0000247 name: positive regulation of cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators] synonym: "activation of progression through cell cycle" NARROW [] synonym: "positive regulation of cell cycle progression" EXACT [] synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through cell cycle" NARROW [] synonym: "up regulation of progression through cell cycle" EXACT [] synonym: "up-regulation of progression through cell cycle" EXACT [] synonym: "upregulation of progression through cell cycle" EXACT [] xref: GO:0045787 is_a: CCO:P0000346 ! regulation of cell cycle is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN relationship: positively_regulates CCO:P0000066 ! cell cycle [Term] id: CCO:P0000248 name: negative regulation of meiosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "down regulation of meiosis" EXACT [] synonym: "down-regulation of meiosis" EXACT [] synonym: "downregulation of meiosis" EXACT [] synonym: "inhibition of meiosis" NARROW [] xref: GO:0045835 is_a: CCO:P0000226 ! regulation of meiosis is_a: CCO:P0002853 ! negative regulation of cellular process relationship: negatively_regulates CCO:P0000117 ! meiosis [Term] id: CCO:P0000249 name: positive regulation of meiosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "activation of meiosis" NARROW [] synonym: "stimulation of meiosis" NARROW [] synonym: "up regulation of meiosis" EXACT [] synonym: "up-regulation of meiosis" EXACT [] synonym: "upregulation of meiosis" EXACT [] xref: GO:0045836 is_a: CCO:P0000226 ! regulation of meiosis is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0001936 ! NPM2_HUMAN relationship: positively_regulates CCO:P0000117 ! meiosis [Term] id: CCO:P0000250 name: negative regulation of mitosis namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of mitosis" EXACT [] synonym: "down-regulation of mitosis" EXACT [] synonym: "downregulation of mitosis" EXACT [] synonym: "inhibition of mitosis" NARROW [] xref: GO:0045839 is_a: CCO:P0000099 ! regulation of mitosis is_a: CCO:P0000246 ! negative regulation of cell cycle relationship: has_participant CCO:B0002171 ! AKIP_HUMAN relationship: negatively_regulates CCO:P0000081 ! mitosis [Term] id: CCO:P0000251 name: positive regulation of mitosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "activation of mitosis" NARROW [] synonym: "mitogenic activity" NARROW [] synonym: "stimulation of mitosis" NARROW [] synonym: "up regulation of mitosis" EXACT [] synonym: "up-regulation of mitosis" EXACT [] synonym: "upregulation of mitosis" EXACT [] xref: GO:0045840 is_a: CCO:P0000099 ! regulation of mitosis is_a: CCO:P0000247 ! positive regulation of cell cycle relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001508 ! CD28_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001927 ! Q70WG0_HUMAN relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: has_participant CCO:B0005870 ! TGFA_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0043823 ! EDN3_HUMAN relationship: positively_regulates CCO:P0000081 ! mitosis [Term] id: CCO:P0000252 name: negative regulation of mitotic metaphase/anaphase transition namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the mitotic metaphase to anaphase transition." [GOC:go_curators] synonym: "down regulation of mitotic metaphase/anaphase transition" EXACT [] synonym: "down-regulation of mitotic metaphase/anaphase transition" EXACT [] synonym: "downregulation of mitotic metaphase/anaphase transition" EXACT [] synonym: "inhibition of mitotic metaphase/anaphase transition" NARROW [] xref: GO:0045841 is_a: CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition is_a: CCO:P0000250 ! negative regulation of mitosis relationship: negatively_regulates CCO:P0000102 ! mitotic metaphase/anaphase transition [Term] id: CCO:P0000253 name: positive regulation of mitotic metaphase/anaphase transition namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the mitotic metaphase to anaphase transition." [GOC:go_curators] synonym: "activation of mitotic metaphase/anaphase transition" NARROW [] synonym: "stimulation of mitotic metaphase/anaphase transition" NARROW [] synonym: "up regulation of mitotic metaphase/anaphase transition" EXACT [] synonym: "up-regulation of mitotic metaphase/anaphase transition" EXACT [] synonym: "upregulation of mitotic metaphase/anaphase transition" EXACT [] xref: GO:0045842 is_a: CCO:P0000162 ! regulation of mitotic metaphase/anaphase transition is_a: CCO:P0000251 ! positive regulation of mitosis relationship: has_participant CCO:B0001787 ! ESPL1_HUMAN relationship: has_participant CCO:B0001807 ! DLGP5_HUMAN relationship: positively_regulates CCO:P0000102 ! mitotic metaphase/anaphase transition [Term] id: CCO:P0000254 name: negative regulation of sister chromatid cohesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sister chromatid cohesion." [GOC:go_curators] synonym: "down regulation of sister chromatid cohesion" EXACT [] synonym: "down-regulation of sister chromatid cohesion" EXACT [] synonym: "downregulation of sister chromatid cohesion" EXACT [] synonym: "inhibition of sister chromatid cohesion" NARROW [] xref: GO:0045875 is_a: CCO:P0000077 ! regulation of sister chromatid cohesion is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis relationship: has_participant CCO:B0001442 ! RECQ4_HUMAN relationship: has_participant CCO:B0001787 ! ESPL1_HUMAN relationship: negatively_regulates CCO:P0000076 ! sister chromatid cohesion [Term] id: CCO:P0000255 name: positive regulation of sister chromatid cohesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion." [GOC:go_curators] synonym: "activation of sister chromatid cohesion" NARROW [] synonym: "stimulation of sister chromatid cohesion" NARROW [] synonym: "up regulation of sister chromatid cohesion" EXACT [] synonym: "up-regulation of sister chromatid cohesion" EXACT [] synonym: "upregulation of sister chromatid cohesion" EXACT [] xref: GO:0045876 is_a: CCO:P0000077 ! regulation of sister chromatid cohesion is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis relationship: positively_regulates CCO:P0000076 ! sister chromatid cohesion [Term] id: CCO:P0000256 name: regulation of transcription, mitotic namespace: biological_process def: "A cell cycle process that modulates the frequency, rate or extent of transcription during mitosis." [GOC:go_curators] synonym: "mitotic regulation of transcription" EXACT [] xref: GO:0045896 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: part_of CCO:P0000081 ! mitosis [Term] id: CCO:P0000257 name: positive regulation of transcription, mitotic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription during mitosis." [GOC:go_curators] synonym: "activation of transcription, mitotic" NARROW [] synonym: "mitotic activation of transcription" EXACT [] synonym: "stimulation of transcription, mitotic" NARROW [] synonym: "up regulation of transcription, mitotic" EXACT [] synonym: "up-regulation of transcription, mitotic" EXACT [] synonym: "upregulation of transcription, mitotic" EXACT [] xref: GO:0045897 is_a: CCO:P0000256 ! regulation of transcription, mitotic is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:P0000258 name: negative regulation of mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through mitotic cell cycle" EXACT [] synonym: "downregulation of progression through mitotic cell cycle" EXACT [] synonym: "inhibition of progression through mitotic cell cycle" NARROW [] synonym: "negative regulation of mitotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: GO:0045930 is_a: CCO:P0000138 ! regulation of mitotic cell cycle is_a: CCO:P0000246 ! negative regulation of cell cycle relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0001736 ! DLG1_HUMAN relationship: has_participant CCO:B0001778 ! BTG3_HUMAN relationship: has_participant CCO:B0002174 ! BTG4_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: negatively_regulates CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000259 name: positive regulation of mitotic cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of progression through mitotic cell cycle" NARROW [] synonym: "positive regulation of mitotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through mitotic cell cycle" NARROW [] synonym: "up regulation of progression through mitotic cell cycle" EXACT [] synonym: "up-regulation of progression through mitotic cell cycle" EXACT [] synonym: "upregulation of progression through mitotic cell cycle" EXACT [] xref: GO:0045931 is_a: CCO:P0000138 ! regulation of mitotic cell cycle is_a: CCO:P0000247 ! positive regulation of cell cycle relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0024005 ! UBP22_HUMAN relationship: has_participant CCO:B0032819 ! ASNS_HUMAN relationship: positively_regulates CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000260 name: negative regulation of mitotic cell cycle, embryonic namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through embryonic mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through embryonic mitotic cell cycle" EXACT [] synonym: "downregulation of progression through embryonic mitotic cell cycle" EXACT [] synonym: "inhibition of progression through embryonic mitotic cell cycle" NARROW [] synonym: "negative regulation of embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of embryonic mitotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: GO:0045976 is_a: CCO:P0000145 ! regulation of mitotic cell cycle, embryonic is_a: CCO:P0000258 ! negative regulation of mitotic cell cycle relationship: negatively_regulates CCO:P0000241 ! mitotic cell cycle, embryonic [Term] id: CCO:P0000261 name: positive regulation of mitotic cell cycle, embryonic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of mitotic cell cycle, embryonic" NARROW [] synonym: "positive regulation of embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of embryonic mitotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through embryonic mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of mitotic cell cycle, embryonic" NARROW [] synonym: "up regulation of mitotic cell cycle, embryonic" EXACT [] synonym: "up-regulation of mitotic cell cycle, embryonic" EXACT [] synonym: "upregulation of mitotic cell cycle, embryonic" EXACT [] xref: GO:0045977 is_a: CCO:P0000145 ! regulation of mitotic cell cycle, embryonic is_a: CCO:P0000259 ! positive regulation of mitotic cell cycle relationship: positively_regulates CCO:P0000241 ! mitotic cell cycle, embryonic [Term] id: CCO:P0000262 name: negative regulation of preblastoderm mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through preblastoderm mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through preblastoderm mitotic cell cycle" EXACT [] synonym: "downregulation of progression through preblastoderm mitotic cell cycle" EXACT [] synonym: "inhibition of progression through preblastoderm mitotic cell cycle" NARROW [] synonym: "negative regulation of preblastoderm mitotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through preblastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: GO:0046001 is_a: CCO:P0000139 ! regulation of preblastoderm mitotic cell cycle is_a: CCO:P0000260 ! negative regulation of mitotic cell cycle, embryonic relationship: negatively_regulates CCO:P0000223 ! preblastoderm mitotic cell cycle [Term] id: CCO:P0000263 name: positive regulation of preblastoderm mitotic cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of progression through preblastoderm mitotic cell cycle" NARROW [] synonym: "positive regulation of preblastoderm mitotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through preblastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through preblastoderm mitotic cell cycle" NARROW [] synonym: "up regulation of progression through preblastoderm mitotic cell cycle" EXACT [] synonym: "up-regulation of progression through preblastoderm mitotic cell cycle" EXACT [] synonym: "upregulation of progression through preblastoderm mitotic cell cycle" EXACT [] xref: GO:0046002 is_a: CCO:P0000139 ! regulation of preblastoderm mitotic cell cycle is_a: CCO:P0000261 ! positive regulation of mitotic cell cycle, embryonic relationship: positively_regulates CCO:P0000223 ! preblastoderm mitotic cell cycle [Term] id: CCO:P0000264 name: negative regulation of syncytial blastoderm mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] synonym: "downregulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] synonym: "inhibition of progression through syncytial blastoderm mitotic cell cycle" NARROW [] synonym: "negative regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of syncytial blastoderm cell cycle progression" EXACT [] xref: GO:0046003 is_a: CCO:P0000140 ! regulation of syncytial blastoderm mitotic cell cycle is_a: CCO:P0000260 ! negative regulation of mitotic cell cycle, embryonic relationship: negatively_regulates CCO:P0000224 ! syncytial blastoderm mitotic cell cycle [Term] id: CCO:P0000265 name: positive regulation of syncytial blastoderm mitotic cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of progression through syncytial blastoderm mitotic cell cycle" NARROW [] synonym: "positive regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of syncytial blastoderm cell cycle progression" EXACT [] synonym: "stimulation of progression through syncytial blastoderm mitotic cell cycle" NARROW [] synonym: "up regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] synonym: "up-regulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] synonym: "upregulation of progression through syncytial blastoderm mitotic cell cycle" EXACT [] xref: GO:0046004 is_a: CCO:P0000140 ! regulation of syncytial blastoderm mitotic cell cycle is_a: CCO:P0000261 ! positive regulation of mitotic cell cycle, embryonic relationship: positively_regulates CCO:P0000224 ! syncytial blastoderm mitotic cell cycle [Term] id: CCO:P0000266 name: regulation of transcription from RNA polymerase I promoter, mitotic namespace: biological_process def: "A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators] synonym: "mitotic regulation of transcription from Pol I promoter" EXACT [] synonym: "regulation of transcription from Pol I promoter, mitotic" EXACT [] xref: GO:0046017 is_a: CCO:P0000256 ! regulation of transcription, mitotic is_a: CCO:P0000656 ! regulation of transcription from RNA polymerase I promoter [Term] id: CCO:P0000267 name: positive regulation of transcription from RNA polymerase I promoter, mitotic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter during mitosis." [GOC:go_curators] synonym: "activation of transcription from RNA polymerase I promoter, mitotic" NARROW [] synonym: "mitotic activation of transcription from Pol I promoter" EXACT [] synonym: "positive regulation of transcription from Pol I promoter, mitotic" EXACT [] synonym: "stimulation of transcription from RNA polymerase I promoter, mitotic" NARROW [] synonym: "up regulation of transcription from RNA polymerase I promoter, mitotic" EXACT [] synonym: "up-regulation of transcription from RNA polymerase I promoter, mitotic" EXACT [] synonym: "upregulation of transcription from RNA polymerase I promoter, mitotic" EXACT [] xref: GO:0046018 is_a: CCO:P0000257 ! positive regulation of transcription, mitotic is_a: CCO:P0000266 ! regulation of transcription from RNA polymerase I promoter, mitotic is_a: CCO:P0002627 ! positive regulation of transcription from RNA polymerase I promoter [Term] id: CCO:P0000268 name: regulation of transcription from RNA polymerase II promoter, mitotic namespace: biological_process def: "A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators] synonym: "mitotic regulation of transcription from Pol II promoter" EXACT [] synonym: "regulation of transcription from Pol II promoter, mitotic" EXACT [] xref: GO:0046021 is_a: CCO:P0000256 ! regulation of transcription, mitotic is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:P0000269 name: positive regulation of transcription from RNA polymerase II promoter, mitotic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter during mitosis." [GOC:go_curators] synonym: "activation of transcription from RNA polymerase II promoter, mitotic" NARROW [] synonym: "mitotic activation of transcription from Pol II promoter" EXACT [] synonym: "positive regulation of transcription from Pol II promoter, mitotic" EXACT [] synonym: "stimulation of transcription from RNA polymerase II promoter, mitotic" NARROW [] synonym: "up regulation of transcription from RNA polymerase II promoter, mitotic" EXACT [] synonym: "up-regulation of transcription from RNA polymerase II promoter, mitotic" EXACT [] synonym: "upregulation of transcription from RNA polymerase II promoter, mitotic" EXACT [] xref: GO:0046022 is_a: CCO:P0000257 ! positive regulation of transcription, mitotic is_a: CCO:P0000268 ! regulation of transcription from RNA polymerase II promoter, mitotic is_a: CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0001522 ! FOSL1_HUMAN relationship: has_participant CCO:B0002146 ! TF7L1_HUMAN [Term] id: CCO:P0000270 name: regulation of transcription from RNA polymerase III promoter, mitotic namespace: biological_process def: "A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators] synonym: "mitotic regulation of transcription from Pol III promoter" EXACT [] synonym: "regulation of transcription from Pol III promoter, mitotic" EXACT [] xref: GO:0046023 is_a: CCO:P0000256 ! regulation of transcription, mitotic is_a: CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter [Term] id: CCO:P0000271 name: positive regulation of transcription from RNA polymerase III promoter, mitotic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III promoter during mitosis." [GOC:go_curators] synonym: "activation of transcription from RNA polymerase III promoter, mitotic" NARROW [] synonym: "mitotic activation of transcription from Pol III promoter" EXACT [] synonym: "positive regulation of transcription from Pol III promoter, mitotic" EXACT [] synonym: "stimulation of transcription from RNA polymerase III promoter, mitotic" NARROW [] synonym: "up regulation of transcription from RNA polymerase III promoter, mitotic" EXACT [] synonym: "up-regulation of transcription from RNA polymerase III promoter, mitotic" EXACT [] synonym: "upregulation of transcription from RNA polymerase III promoter, mitotic" EXACT [] xref: GO:0046024 is_a: CCO:P0000257 ! positive regulation of transcription, mitotic is_a: CCO:P0000270 ! regulation of transcription from RNA polymerase III promoter, mitotic is_a: CCO:P0002629 ! positive regulation of transcription from RNA polymerase III promoter [Term] id: CCO:P0000272 name: regulation of centriole replication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole." [GOC:ai] xref: GO:0046599 is_a: CCO:P0000278 ! regulation of centrosome cycle is_a: CCO:P0001703 ! regulation of microtubule-based process relationship: regulates CCO:P0000109 ! centriole replication [Term] id: CCO:P0000273 name: negative regulation of centriole replication namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of centriole replication." [GOC:ai] synonym: "down regulation of centriole replication" EXACT [] synonym: "down-regulation of centriole replication" EXACT [] synonym: "downregulation of centriole replication" EXACT [] synonym: "inhibition of centriole replication" NARROW [] xref: GO:0046600 is_a: CCO:P0000272 ! regulation of centriole replication is_a: CCO:P0000279 ! negative regulation of centrosome cycle is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: negatively_regulates CCO:P0000109 ! centriole replication [Term] id: CCO:P0000274 name: positive regulation of centriole replication namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of centriole replication." [GOC:ai] synonym: "activation of centriole replication" NARROW [] synonym: "stimulation of centriole replication" NARROW [] synonym: "up regulation of centriole replication" EXACT [] synonym: "up-regulation of centriole replication" EXACT [] synonym: "upregulation of centriole replication" EXACT [] xref: GO:0046601 is_a: CCO:P0000272 ! regulation of centriole replication is_a: CCO:P0000280 ! positive regulation of centrosome cycle is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis relationship: positively_regulates CCO:P0000109 ! centriole replication [Term] id: CCO:P0000275 name: regulation of mitotic centrosome separation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis." [GOC:ai] xref: GO:0046602 is_a: CCO:P0000278 ! regulation of centrosome cycle relationship: regulates CCO:P0000110 ! mitotic centrosome separation [Term] id: CCO:P0000276 name: negative regulation of mitotic centrosome separation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of centrosome separation." [GOC:ai] synonym: "down regulation of mitotic centrosome separation" EXACT [] synonym: "down-regulation of mitotic centrosome separation" EXACT [] synonym: "downregulation of mitotic centrosome separation" EXACT [] synonym: "inhibition of mitotic centrosome separation" NARROW [] xref: GO:0046603 is_a: CCO:P0000275 ! regulation of mitotic centrosome separation is_a: CCO:P0000279 ! negative regulation of centrosome cycle relationship: negatively_regulates CCO:P0000110 ! mitotic centrosome separation [Term] id: CCO:P0000277 name: positive regulation of mitotic centrosome separation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of centrosome separation." [GOC:ai] synonym: "activation of mitotic centrosome separation" NARROW [] synonym: "stimulation of mitotic centrosome separation" NARROW [] synonym: "up regulation of mitotic centrosome separation" EXACT [] synonym: "up-regulation of mitotic centrosome separation" EXACT [] synonym: "upregulation of mitotic centrosome separation" EXACT [] xref: GO:0046604 is_a: CCO:P0000275 ! regulation of mitotic centrosome separation is_a: CCO:P0000280 ! positive regulation of centrosome cycle relationship: positively_regulates CCO:P0000110 ! mitotic centrosome separation [Term] id: CCO:P0000278 name: regulation of centrosome cycle namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation." [GOC:ai] xref: GO:0046605 is_a: CCO:P0000382 ! regulation of cell cycle process is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis relationship: regulates CCO:P0000108 ! centrosome cycle [Term] id: CCO:P0000279 name: negative regulation of centrosome cycle namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the centrosome cycle." [GOC:ai] synonym: "down regulation of centrosome cycle" EXACT [] synonym: "down-regulation of centrosome cycle" EXACT [] synonym: "downregulation of centrosome cycle" EXACT [] synonym: "inhibition of centrosome cycle" NARROW [] xref: GO:0046606 is_a: CCO:P0000278 ! regulation of centrosome cycle is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis relationship: negatively_regulates CCO:P0000108 ! centrosome cycle [Term] id: CCO:P0000280 name: positive regulation of centrosome cycle namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the centrosome cycle." [GOC:ai] synonym: "activation of centrosome cycle" NARROW [] synonym: "stimulation of centrosome cycle" NARROW [] synonym: "up regulation of centrosome cycle" EXACT [] synonym: "up-regulation of centrosome cycle" EXACT [] synonym: "upregulation of centrosome cycle" EXACT [] xref: GO:0046607 is_a: CCO:P0000278 ! regulation of centrosome cycle is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis relationship: positively_regulates CCO:P0000108 ! centrosome cycle [Term] id: CCO:P0000282 name: chiasma formation namespace: biological_process def: "The cell cycle process whereby a connection between chromatids forms, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids." [http://www.onelook.com] xref: GO:0051026 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000120 ! synapsis [Term] id: CCO:P0000286 name: meiotic nuclear envelope disassembly namespace: biological_process def: "The cell cycle process whereby the controlled breakdown of the nuclear envelope during meiotic cell division occurs." [GOC:bf] synonym: "meiotic nuclear envelope breakdown" EXACT [] synonym: "meiotic nuclear envelope catabolism" EXACT [] synonym: "meiotic nuclear envelope degradation" EXACT [] xref: GO:0051078 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000287 name: meiosis I nuclear envelope disassembly namespace: biological_process def: "The controlled breakdown of the nuclear envelope during the first division of meiosis." [GOC:bf] synonym: "meiosis I nuclear envelope breakdown" EXACT [] synonym: "meiosis I nuclear envelope catabolism" EXACT [] synonym: "meiosis I nuclear envelope degradation" EXACT [] xref: GO:0051079 is_a: CCO:P0000286 ! meiotic nuclear envelope disassembly relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000288 name: meiosis II nuclear envelope disassembly namespace: biological_process def: "The controlled breakdown of the nuclear envelope during the second division of meiosis." [GOC:bf] synonym: "meiosis II nuclear envelope breakdown" EXACT [] synonym: "meiosis II nuclear envelope catabolism" EXACT [] synonym: "meiosis II nuclear envelope degradation" EXACT [] xref: GO:0051080 is_a: CCO:P0000286 ! meiotic nuclear envelope disassembly relationship: part_of CCO:P0000126 ! meiosis II [Term] id: CCO:P0000289 name: meiotic sister chromatid cohesion namespace: biological_process def: "The cell cycle process whereby sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis." [GOC:ai] xref: GO:0051177 is_a: CCO:P0000076 ! sister chromatid cohesion relationship: part_of CCO:P0000118 ! meiosis I relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000290 name: meiotic chromosome decondensation namespace: biological_process def: "The cell cycle process whereby chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells." [GOC:ai] xref: GO:0051178 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000291 name: mitotic spindle disassembly namespace: biological_process def: "The controlled breakdown of the spindle during a mitotic cell cycle." [GOC:ai] synonym: "mitotic spindle breakdown" EXACT [] synonym: "mitotic spindle catabolism" EXACT [] synonym: "mitotic spindle degradation" EXACT [] synonym: "spindle breakdown during mitosis" EXACT [] synonym: "spindle degradation during mitosis" EXACT [] synonym: "spindle disassembly during mitosis" EXACT [] xref: GO:0051228 is_a: CCO:P0000068 ! mitotic spindle organization and biogenesis is_a: CCO:P0000393 ! spindle disassembly [Term] id: CCO:P0000292 name: meiotic spindle disassembly namespace: biological_process def: "The controlled breakdown of the spindle during a meiotic cell cycle." [GOC:ai] synonym: "meiotic spindle breakdown" EXACT [] synonym: "meiotic spindle catabolism" EXACT [] synonym: "meiotic spindle degradation" EXACT [] synonym: "spindle breakdown during meiosis" EXACT [] synonym: "spindle degradation during meiosis" EXACT [] synonym: "spindle disassembly during meiosis" EXACT [] xref: GO:0051229 is_a: CCO:P0000030 ! meiotic spindle organization and biogenesis is_a: CCO:P0000393 ! spindle disassembly [Term] id: CCO:P0000293 name: spindle elongation namespace: biological_process def: "The cell cycle process whereby the distance is lengthened between poles of the spindle." [GOC:ai] xref: GO:0051231 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000385 ! spindle organization and biogenesis [Term] id: CCO:P0000294 name: meiotic spindle elongation namespace: biological_process def: "The lengthening of the distance between poles of the spindle during a meiotic cell cycle." [GOC:ai] synonym: "spindle elongation during meiosis" EXACT [] xref: GO:0051232 is_a: CCO:P0000293 ! spindle elongation relationship: part_of CCO:P0000030 ! meiotic spindle organization and biogenesis [Term] id: CCO:P0000295 name: spindle midzone assembly namespace: biological_process def: "The cell cycle process whereby aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap." [GOC:ai, PMID:15296749] synonym: "spindle midzone biogenesis" EXACT [] synonym: "spindle midzone biosynthesis" EXACT [] synonym: "spindle midzone formation" EXACT [] xref: GO:0051255 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000392 ! spindle assembly [Term] id: CCO:P0000296 name: spindle midzone assembly involved in mitosis namespace: biological_process def: "The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, during the process of mitosis." [GOC:ai, GOC:rg, GOC:tb] synonym: "mitotic spindle midzone assembly" RELATED [] synonym: "mitotic spindle midzone biogenesis" EXACT [] synonym: "mitotic spindle midzone biosynthesis" EXACT [] synonym: "mitotic spindle midzone formation" EXACT [] synonym: "spindle midzone biogenesis involved in mitosis" EXACT [] synonym: "spindle midzone formation involved in mitosis" EXACT [] xref: GO:0051256 is_a: CCO:P0000295 ! spindle midzone assembly [Term] id: CCO:P0000297 name: spindle midzone assembly involved in meiosis namespace: biological_process def: "The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, during the process of meiosis." [GOC:ai, GOC:rg, GOC:tb] synonym: "meiotic spindle midzone assembly" RELATED [] synonym: "meiotic spindle midzone biogenesis" EXACT [] synonym: "meiotic spindle midzone biosynthesis" EXACT [] synonym: "meiotic spindle midzone formation" EXACT [] synonym: "spindle midzone biogenesis involved in meiosis" EXACT [] synonym: "spindle midzone biosynthesis involved in meiosis" EXACT [] synonym: "spindle midzone formation involved in meiosis" EXACT [] xref: GO:0051257 is_a: CCO:P0000295 ! spindle midzone assembly [Term] id: CCO:P0000298 name: establishment of meiotic spindle localization namespace: biological_process def: "The cell cycle process whereby the directed movement of the meiotic spindle to a specific location in the cell occurs." [GOC:ai] synonym: "meiotic spindle positioning" EXACT [] synonym: "spindle positioning during meiosis" EXACT [] xref: GO:0051295 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0043838 ! FMN2_HUMAN relationship: part_of CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000299 name: establishment of meiotic spindle orientation namespace: biological_process def: "Any process that set the alignment of meiotic spindle relative to other cellular structures." [GOC:ai] synonym: "establishment of spindle orientation during meiosis" EXACT [] synonym: "meiotic spindle orientation" EXACT [] synonym: "orienting of meiotic spindle" EXACT [] xref: GO:0051296 is_a: CCO:P0000298 ! establishment of meiotic spindle localization [Term] id: CCO:P0000300 name: centrosome duplication namespace: biological_process def: "The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:ai] synonym: "centrosome replication" EXACT [] xref: GO:0051298 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001389 ! CE110_HUMAN relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001918 ! SAS6_HUMAN relationship: has_participant CCO:B0002088 ! Q99773_HUMAN relationship: has_participant CCO:B0002173 ! NDE1_HUMAN relationship: part_of CCO:P0000108 ! centrosome cycle [Term] id: CCO:P0000301 name: centrosome separation namespace: biological_process def: "The process by which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle." [GOC:ai] xref: GO:0051299 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001961 ! CNTRB_HUMAN relationship: part_of CCO:P0000108 ! centrosome cycle [Term] id: CCO:P0000302 name: spindle pole body organization and biogenesis namespace: biological_process def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome." [GOC:ai, GOC:mah] synonym: "SPB organization and biogenesis" EXACT [] synonym: "spindle pole body organisation and biogenesis" EXACT [] xref: GO:0051300 is_a: CCO:P0000159 ! cell cycle process relationship: has_participant CCO:B0001659 ! KIF11_HUMAN relationship: has_participant CCO:B0001772 ! CKAP5_HUMAN [Term] id: CCO:P0000303 name: chromosome separation namespace: biological_process def: "The cell cycle process whereby paired chromosomes are detached from each other. In budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions." [GOC:ai] xref: GO:0051304 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0000304 name: mitotic sister chromatid separation namespace: biological_process def: "The process by which sister chromatids are physically detached from each other during mitosis." [GOC:ai] synonym: "chromosome separation during mitosis" RELATED [] synonym: "mitotic chromosome separation" RELATED [] synonym: "sister chromatid separation during mitosis" EXACT [] xref: GO:0051306 is_a: CCO:P0000303 ! chromosome separation relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000305 name: meiotic chromosome separation namespace: biological_process def: "The process by which chromosomes are physically detached from each other during meiosis." [GOC:ai] synonym: "chromosome separation during meiosis" EXACT [] xref: GO:0051307 is_a: CCO:P0000303 ! chromosome separation relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000306 name: male meiosis chromosome separation namespace: biological_process def: "The process by which paired chromosomes are physically detached from each other during male meiosis." [GOC:ai] synonym: "chromosome separation during male meiosis" EXACT [] xref: GO:0051308 is_a: CCO:P0000075 ! male meiosis chromosome segregation is_a: CCO:P0000305 ! meiotic chromosome separation [Term] id: CCO:P0000307 name: female meiosis chromosome separation namespace: biological_process def: "The process by which paired chromosomes are physically detached from each other during female meiosis." [GOC:ai] synonym: "chromosome separation during female meiosis" EXACT [] xref: GO:0051309 is_a: CCO:P0000153 ! female meiosis chromosome segregation is_a: CCO:P0000305 ! meiotic chromosome separation [Term] id: CCO:P0000308 name: meiotic metaphase plate congression namespace: biological_process def: "The cell cycle process whereby chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis." [GOC:ai] synonym: "metaphase plate congression during meiosis" EXACT [] xref: GO:0051311 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0003080 ! metaphase plate congression relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000309 name: attachment of spindle microtubules to mitotic chromosome namespace: biological_process def: "The cell cycle process whereby spindle microtubules become physically associated with a chromosome during mitosis." [GOC:ai] xref: GO:0051314 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0003081 ! attachment of spindle microtubules to chromosome relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000310 name: attachment of spindle microtubules to kinetochore during mitosis namespace: biological_process def: "The cell cycle process whereby spindle microtubules become physically associated with the proteins making up the kinetochore complex during mitosis. During mitosis, the kinetochores of sister chromosomes are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs." [GOC:ai, GOC:clt] xref: GO:0051315 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000830 ! attachment of spindle microtubules to kinetochore relationship: part_of CCO:P0000002 ! mitotic sister chromatid segregation [Term] id: CCO:P0000311 name: attachment of spindle microtubules to kinetochore during meiotic chromosome segregation namespace: biological_process def: "The cell cycle process whereby spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiotic chromosome segregation." [GOC:ai] synonym: "attachment of spindle microtubules to kinetochore during meiosis" RELATED [] xref: GO:0051316 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0000830 ! attachment of spindle microtubules to kinetochore relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000312 name: attachment of spindle microtubules to meiotic chromosome namespace: biological_process def: "The cell cycle process whereby spindle microtubules become physically associated with a chromosome during meiosis." [GOC:ai] xref: GO:0051317 is_a: CCO:P0000159 ! cell cycle process is_a: CCO:P0003081 ! attachment of spindle microtubules to chromosome relationship: part_of CCO:P0000237 ! meiotic chromosome segregation [Term] id: CCO:P0000313 name: G1 phase namespace: biological_process def: "Progression through G1 phase, one of two 'gap' phases in the cell cycle; G1 is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis." [GOC:ai] xref: GO:0051318 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001842 ! BMCC1_HUMAN relationship: part_of CCO:P0000320 ! interphase [Term] id: CCO:P0000314 name: G2 phase namespace: biological_process def: "Progression through G2 phase, one of two 'gap' phases in the cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis)." [GOC:ai] xref: GO:0051319 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000320 ! interphase [Term] id: CCO:P0000315 name: S phase namespace: biological_process def: "Progression through S phase, the part of the cell cycle during which DNA synthesis takes place." [GOC:ai] xref: GO:0051320 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000320 ! interphase [Term] id: CCO:P0000316 name: meiotic cell cycle namespace: biological_process def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell." [GOC:ai] xref: GO:0051321 is_a: CCO:P0000066 ! cell cycle relationship: has_participant CCO:B0001794 ! NUMA1_HUMAN [Term] id: CCO:P0000317 name: anaphase namespace: biological_process def: "Progression through anaphase, the third stage of chromosome segregation in the cell cycle. Canonically, sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle." [http://www.onelook.com] xref: GO:0051322 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000039 ! M phase [Term] id: CCO:P0000318 name: metaphase namespace: biological_process def: "Progression through metaphase, the second stage of chromosome segregation in the cell cycle. Canonically, chromosomes become aligned on the equatorial plate of the cell." [http://www.onelook.com] xref: GO:0051323 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000039 ! M phase [Term] id: CCO:P0000319 name: prophase namespace: biological_process def: "Progression through prophase, the first stage of chromosome segregation in the cell cycle. Canonically, chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell." [GOC:ai] xref: GO:0051324 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000039 ! M phase [Term] id: CCO:P0000320 name: interphase namespace: biological_process def: "Progression through interphase, the stage of cell cycle between successive rounds of chromosome segregation. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [http://www.onelook.com] synonym: "karyostasis" EXACT [] synonym: "resting phase" BROAD [] xref: GO:0051325 is_a: CCO:P0000160 ! cell cycle phase relationship: has_participant CCO:B0001501 ! K2C7_HUMAN [Term] id: CCO:P0000321 name: telophase namespace: biological_process def: "Progression through telophase, the last stage of chromosome segregation in the cell cycle. Canonically, telophase begins when the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." [http://www.onelook.com] xref: GO:0051326 is_a: CCO:P0000160 ! cell cycle phase relationship: part_of CCO:P0000039 ! M phase [Term] id: CCO:P0000322 name: M phase of meiotic cell cycle namespace: biological_process def: "Progression through M phase, the part of the meiotic cell cycle during which meiosis takes place." [GOC:ai] xref: GO:0051327 is_a: CCO:P0000039 ! M phase relationship: part_of CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000323 name: interphase of meiotic cell cycle namespace: biological_process def: "Progression through interphase, the stage of cell cycle between successive rounds of meiosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [GOC:ai] xref: GO:0051328 is_a: CCO:P0000320 ! interphase relationship: part_of CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000324 name: interphase of mitotic cell cycle namespace: biological_process def: "Progression through interphase, the stage of cell cycle between successive rounds of mitosis. Canonically, interphase is the stage of the cell cycle during which the biochemical and physiologic functions of the cell are performed and replication of chromatin occurs." [GOC:ai] xref: GO:0051329 is_a: CCO:P0000320 ! interphase relationship: has_participant CCO:B0001427 ! KTNA1_HUMAN relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: part_of CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000325 name: G1 phase of meiotic cell cycle namespace: biological_process def: "Progression through G1 phase, one of two 'gap' phases in the meiotic cell cycle; G1 is the interval between the completion of meiosis and the beginning of DNA synthesis." [GOC:ai] xref: GO:0051330 is_a: CCO:P0000313 ! G1 phase relationship: part_of CCO:P0000323 ! interphase of meiotic cell cycle [Term] id: CCO:P0000326 name: G2 phase of meiotic cell cycle namespace: biological_process def: "Progression through G2 phase, one of two 'gap' phases in the meiotic cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of meiosis." [GOC:ai] xref: GO:0051331 is_a: CCO:P0000314 ! G2 phase relationship: part_of CCO:P0000323 ! interphase of meiotic cell cycle [Term] id: CCO:P0000327 name: S phase of meiotic cell cycle namespace: biological_process def: "Progression through S phase, the part of the meiotic cell cycle during which DNA synthesis takes place." [GOC:ai] xref: GO:0051332 is_a: CCO:P0000315 ! S phase relationship: part_of CCO:P0000323 ! interphase of meiotic cell cycle [Term] id: CCO:P0000328 name: meiotic nuclear envelope reassembly namespace: biological_process def: "The cell cycle process whereby the reformation of the nuclear envelope during meiosis occurs." [GOC:ai] xref: GO:0051333 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000329 name: meiosis I nuclear envelope reassembly namespace: biological_process def: "The reformation of the nuclear envelope during meiosis I." [GOC:ai] xref: GO:0051334 is_a: CCO:P0000328 ! meiotic nuclear envelope reassembly relationship: part_of CCO:P0000118 ! meiosis I [Term] id: CCO:P0000330 name: meiosis II nuclear envelope reassembly namespace: biological_process def: "The reformation of the nuclear envelope during meiosis II." [GOC:ai] xref: GO:0051335 is_a: CCO:P0000328 ! meiotic nuclear envelope reassembly relationship: part_of CCO:P0000126 ! meiosis II [Term] id: CCO:P0000331 name: interphase microtubule nucleation by interphase microtubule organizing center namespace: biological_process def: "The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation." [GOC:ai] synonym: "IMTOC-mediated microtubule nucleation during interphase" EXACT [] synonym: "interphase microtubule nucleation by interphase microtubule organising centre" EXACT [] synonym: "interphase microtubule organizing center-mediated microtubule nucleation during interphase" EXACT [] synonym: "microtubule nucleation during interphase by IMTOC" EXACT [] synonym: "microtubule nucleation during interphase by interphase microtubule organizing center" EXACT [] xref: GO:0051415 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000320 ! interphase [Term] id: CCO:P0000332 name: spindle pole body maturation namespace: biological_process def: "Any process by which the newly duplicated spindle pole body (SPB) is processed to attain its full functional capacity. In S. pombe, early maturation includes increase in size of the lamellar bodies, invagination of the nuclear envelope, and accumulation of material in a pocket under the SPB. Late maturation includes fenestration of the nuclear envelope, SPB separation and entry into the nucleus, giving rise to the spindle." [GOC:ai, PMID:15132994, PMID:15385623] synonym: "SPB maturation" EXACT [] xref: GO:0051426 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000302 ! spindle pole body organization and biogenesis [Term] id: CCO:P0000333 name: negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai, GOC:tb] synonym: "anaphase promoting complex inhibition during mitotic cell cycle" NARROW [] synonym: "anaphase-promoting complex inhibition during mitotic cell cycle" NARROW [] synonym: "APC inhibition during mitotic cell cycle" NARROW [] synonym: "down regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [] synonym: "down-regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [] synonym: "downregulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [] synonym: "inhibition of ubiquitin ligase activity during mitotic cell cycle" NARROW [] synonym: "mitotic anaphase promoting complex inhibition" NARROW [] synonym: "mitotic anaphase promoting complex inhibitor" NARROW [] synonym: "mitotic anaphase-promoting complex inhibition" NARROW [] synonym: "mitotic anaphase-promoting complex inhibitor" NARROW [] synonym: "mitotic APC inhibition" NARROW [] synonym: "mitotic APC inhibitor" NARROW [] synonym: "mitotic SCF complex inhibitor" NARROW [] synonym: "mitotic ubiquitin ligase inhibitor" NARROW [] synonym: "negative regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [GOC:tb] xref: GO:0051436 xref: Reactome:141405 xref: Reactome:174079 xref: Reactome:174084 xref: Reactome:174097 xref: Reactome:174139 xref: Reactome:174235 xref: Reactome:174251 xref: Reactome:205333 xref: Reactome:205338 xref: Reactome:207432 xref: Reactome:210208 xref: Reactome:210209 xref: Reactome:211754 xref: Reactome:211831 xref: Reactome:214680 xref: Reactome:214685 xref: Reactome:217035 xref: Reactome:220042 xref: Reactome:220043 xref: Reactome:221521 xref: Reactome:221596 xref: Reactome:224156 xref: Reactome:224161 xref: Reactome:225859 xref: Reactome:228630 xref: Reactome:228631 xref: Reactome:230140 xref: Reactome:230196 xref: Reactome:232620 xref: Reactome:232625 xref: Reactome:234526 xref: Reactome:236793 xref: Reactome:236794 xref: Reactome:238166 xref: Reactome:238230 xref: Reactome:242235 xref: Reactome:243841 xref: Reactome:243842 xref: Reactome:244755 xref: Reactome:244807 xref: Reactome:248864 xref: Reactome:251887 xref: Reactome:252478 xref: Reactome:255069 xref: Reactome:255640 xref: Reactome:258367 xref: Reactome:259034 xref: Reactome:261840 xref: Reactome:262399 xref: Reactome:264678 xref: Reactome:265238 xref: Reactome:267832 xref: Reactome:267834 xref: Reactome:268363 xref: Reactome:272160 xref: Reactome:273334 xref: Reactome:273335 xref: Reactome:274029 xref: Reactome:274074 xref: Reactome:278147 xref: Reactome:279794 xref: Reactome:279795 xref: Reactome:280507 xref: Reactome:280548 xref: Reactome:282372 xref: Reactome:285037 xref: Reactome:285935 xref: Reactome:285936 xref: Reactome:286529 xref: Reactome:286565 is_a: CCO:P0000335 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001396 ! BUB3_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001572 ! CDC27_HUMAN relationship: has_participant CCO:B0001625 ! PSMD8_HUMAN relationship: has_participant CCO:B0001733 ! CDC20_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0001986 ! CDC26_HUMAN relationship: has_participant CCO:B0002066 ! PSMD1_HUMAN relationship: has_participant CCO:B0002125 ! APC1_HUMAN relationship: has_participant CCO:B0002177 ! APC11_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002213 ! APC7_HUMAN relationship: has_participant CCO:B0002214 ! APC5_HUMAN relationship: has_participant CCO:B0002215 ! APC4_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN relationship: has_participant CCO:B0002229 ! FZR_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0005314 ! PRS4_HUMAN relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0006215 ! PSME1_HUMAN relationship: has_participant CCO:B0006219 ! PSB10_HUMAN relationship: has_participant CCO:B0019462 ! UB2D1_HUMAN relationship: has_participant CCO:B0021560 ! PSMD3_HUMAN relationship: has_participant CCO:B0022204 ! PSA5_HUMAN relationship: has_participant CCO:B0023606 ! PSDE_HUMAN relationship: has_participant CCO:B0030768 ! PSA7_HUMAN relationship: has_participant CCO:B0030800 ! PSB2_HUMAN relationship: has_participant CCO:B0030804 ! PSB8_HUMAN relationship: has_participant CCO:B0030806 ! PSB5_HUMAN relationship: has_participant CCO:B0030905 ! PRS10_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN relationship: has_participant CCO:B0031003 ! PSD7_HUMAN relationship: has_participant CCO:B0031007 ! PSB9_HUMAN relationship: has_participant CCO:B0031015 ! PSB6_HUMAN relationship: has_participant CCO:B0032651 ! PSMD6_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN relationship: has_participant CCO:B0038144 ! PSD12_HUMAN relationship: has_participant CCO:B0041239 ! PSMD9_HUMAN relationship: has_participant CCO:B0041240 ! PSD10_HUMAN relationship: has_participant CCO:B0041242 ! PRS6A_HUMAN relationship: has_participant CCO:B0041243 ! PSA2_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN relationship: has_participant CCO:B0041245 ! PSB4_HUMAN relationship: has_participant CCO:B0041246 ! PRS7_HUMAN relationship: has_participant CCO:B0041247 ! PRS6B_HUMAN relationship: has_participant CCO:B0041248 ! UB2E1_HUMAN relationship: has_participant CCO:B0041250 ! PSMD4_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN relationship: has_participant CCO:B0041255 ! PSMD5_HUMAN relationship: has_participant CCO:B0041263 ! PSMF1_HUMAN [Term] id: CCO:P0000334 name: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle namespace: biological_process def: "Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai, GOC:tb] synonym: "activation of ubiquitin ligase activity during mitotic cell cycle" NARROW [] synonym: "mitotic SCF complex activator" NARROW [] synonym: "mitotic ubiquitin ligase activator" NARROW [] synonym: "positive regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [GOC:tb] synonym: "stimulation of ubiquitin ligase activity during mitotic cell cycle" NARROW [] synonym: "up regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [] synonym: "up-regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [] synonym: "upregulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [] xref: GO:0051437 xref: Reactome:174113 xref: Reactome:174238 xref: Reactome:176412 xref: Reactome:204045 xref: Reactome:211808 xref: Reactome:211883 xref: Reactome:213017 xref: Reactome:221572 xref: Reactome:221647 xref: Reactome:222830 xref: Reactome:230174 xref: Reactome:230238 xref: Reactome:231347 xref: Reactome:238210 xref: Reactome:238277 xref: Reactome:239364 xref: Reactome:244788 xref: Reactome:244876 xref: Reactome:249766 xref: Reactome:255691 xref: Reactome:259083 xref: Reactome:262443 xref: Reactome:265278 xref: Reactome:269402 xref: Reactome:274058 xref: Reactome:275312 xref: Reactome:280534 xref: Reactome:283577 xref: Reactome:286552 xref: Reactome:286607 is_a: CCO:P0000335 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0001572 ! CDC27_HUMAN relationship: has_participant CCO:B0001625 ! PSMD8_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0001733 ! CDC20_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0001745 ! PSMD2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0001986 ! CDC26_HUMAN relationship: has_participant CCO:B0002066 ! PSMD1_HUMAN relationship: has_participant CCO:B0002125 ! APC1_HUMAN relationship: has_participant CCO:B0002177 ! APC11_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002213 ! APC7_HUMAN relationship: has_participant CCO:B0002214 ! APC5_HUMAN relationship: has_participant CCO:B0002215 ! APC4_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN relationship: has_participant CCO:B0002229 ! FZR_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0005233 ! PSA1_HUMAN relationship: has_participant CCO:B0005314 ! PRS4_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0005634 ! SKP1_HUMAN relationship: has_participant CCO:B0005991 ! PSA3_HUMAN relationship: has_participant CCO:B0006215 ! PSME1_HUMAN relationship: has_participant CCO:B0006219 ! PSB10_HUMAN relationship: has_participant CCO:B0019462 ! UB2D1_HUMAN relationship: has_participant CCO:B0021560 ! PSMD3_HUMAN relationship: has_participant CCO:B0022204 ! PSA5_HUMAN relationship: has_participant CCO:B0023606 ! PSDE_HUMAN relationship: has_participant CCO:B0030768 ! PSA7_HUMAN relationship: has_participant CCO:B0030800 ! PSB2_HUMAN relationship: has_participant CCO:B0030804 ! PSB8_HUMAN relationship: has_participant CCO:B0030806 ! PSB5_HUMAN relationship: has_participant CCO:B0030905 ! PRS10_HUMAN relationship: has_participant CCO:B0030929 ! PSB3_HUMAN relationship: has_participant CCO:B0030961 ! PSB1_HUMAN relationship: has_participant CCO:B0031003 ! PSD7_HUMAN relationship: has_participant CCO:B0031007 ! PSB9_HUMAN relationship: has_participant CCO:B0031015 ! PSB6_HUMAN relationship: has_participant CCO:B0032651 ! PSMD6_HUMAN relationship: has_participant CCO:B0034007 ! PSB7_HUMAN relationship: has_participant CCO:B0038144 ! PSD12_HUMAN relationship: has_participant CCO:B0041239 ! PSMD9_HUMAN relationship: has_participant CCO:B0041240 ! PSD10_HUMAN relationship: has_participant CCO:B0041242 ! PRS6A_HUMAN relationship: has_participant CCO:B0041243 ! PSA2_HUMAN relationship: has_participant CCO:B0041244 ! PSA4_HUMAN relationship: has_participant CCO:B0041245 ! PSB4_HUMAN relationship: has_participant CCO:B0041246 ! PRS7_HUMAN relationship: has_participant CCO:B0041247 ! PRS6B_HUMAN relationship: has_participant CCO:B0041248 ! UB2E1_HUMAN relationship: has_participant CCO:B0041250 ! PSMD4_HUMAN relationship: has_participant CCO:B0041251 ! PSA6_HUMAN relationship: has_participant CCO:B0041252 ! PSME3_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN relationship: has_participant CCO:B0041255 ! PSMD5_HUMAN relationship: has_participant CCO:B0041263 ! PSMF1_HUMAN [Term] id: CCO:P0000335 name: regulation of ubiquitin-protein ligase activity during mitotic cell cycle namespace: biological_process def: "A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the mitotic cell cycle." [GOC:ai] synonym: "mitotic anaphase-promoting complex regulator" NARROW [] synonym: "mitotic APC regulator" NARROW [] synonym: "mitotic SCF complex regulator" NARROW [] synonym: "mitotic ubiquitin ligase regulator" RELATED [] synonym: "mitotic ubiquitin-protein ligase regulator" RELATED [] synonym: "regulation of ubiquitin ligase activity during mitotic cell cycle" EXACT [GOC:tb] xref: GO:0051439 xref: Reactome:176407 xref: Reactome:176408 xref: Reactome:211657 xref: Reactome:211661 xref: Reactome:221429 xref: Reactome:221433 xref: Reactome:230061 xref: Reactome:230065 xref: Reactome:238081 xref: Reactome:238084 xref: Reactome:244690 xref: Reactome:244694 xref: Reactome:249666 xref: Reactome:249745 xref: Reactome:252447 xref: Reactome:252500 xref: Reactome:255612 xref: Reactome:255673 xref: Reactome:258992 xref: Reactome:259065 xref: Reactome:262363 xref: Reactome:262427 xref: Reactome:265207 xref: Reactome:265263 xref: Reactome:268331 xref: Reactome:268391 xref: Reactome:273978 xref: Reactome:273981 xref: Reactome:280457 xref: Reactome:280460 xref: Reactome:282833 xref: Reactome:286479 xref: Reactome:286539 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000038 ! mitotic cell cycle [Term] id: CCO:P0000336 name: regulation of ubiquitin-protein ligase activity during meiotic cell cycle namespace: biological_process def: "A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [EC:6.3.2.19, GOC:ai, GOC:tb] synonym: "meiotic anaphase-promoting complex regulator" NARROW [] synonym: "meiotic APC regulator" NARROW [] synonym: "meiotic SCF complex regulator" NARROW [] synonym: "meiotic ubiquitin ligase regulator" RELATED [] synonym: "meiotic ubiquitin-protein ligase regulator" RELATED [] synonym: "regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [GOC:tb] xref: GO:0051440 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000337 name: positive regulation of ubiquitin-protein ligase activity during meiotic cell cycle namespace: biological_process def: "Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai, GOC:tb] synonym: "activation of ubiquitin ligase activity during meiotic cell cycle" NARROW [] synonym: "meiotic SCF complex activator" NARROW [] synonym: "meiotic ubiquitin ligase activator" NARROW [] synonym: "positive regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [GOC:tb] synonym: "stimulation of ubiquitin ligase activity during meiotic cell cycle" NARROW [] synonym: "up regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [] synonym: "up-regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [] synonym: "upregulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [] xref: GO:0051441 is_a: CCO:P0000336 ! regulation of ubiquitin-protein ligase activity during meiotic cell cycle [Term] id: CCO:P0000338 name: negative regulation of ubiquitin-protein ligase activity during meiotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle." [GOC:ai, GOC:tb] synonym: "anaphase promoting complex inhibition during meiotic cell cycle" NARROW [] synonym: "anaphase-promoting complex inhibition during meiotic cell cycle" NARROW [] synonym: "APC inhibition during meiotic cell cycle" NARROW [] synonym: "down regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [] synonym: "down-regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [] synonym: "downregulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [] synonym: "inhibition of ubiquitin ligase activity during meiotic cell cycle" NARROW [] synonym: "meiotic anaphase promoting complex inhibition" NARROW [] synonym: "meiotic anaphase promoting complex inhibitor" NARROW [] synonym: "meiotic anaphase-promoting complex inhibition" NARROW [] synonym: "meiotic anaphase-promoting complex inhibitor" NARROW [] synonym: "meiotic APC inhibition" NARROW [] synonym: "meiotic APC inhibitor" NARROW [] synonym: "meiotic SCF complex inhibitor" NARROW [] synonym: "meiotic ubiquitin ligase inhibitor" NARROW [] synonym: "negative regulation of ubiquitin ligase activity during meiotic cell cycle" EXACT [GOC:tb] xref: GO:0051442 is_a: CCO:P0000336 ! regulation of ubiquitin-protein ligase activity during meiotic cell cycle [Term] id: CCO:P0000339 name: regulation of meiotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "control of meiotic cell cycle progression" EXACT [] synonym: "meiotic cell cycle control" EXACT [] synonym: "meiotic cell cycle modulation" EXACT [] synonym: "meiotic cell cycle regulation" EXACT [] synonym: "meiotic cell cycle regulator" RELATED [] synonym: "modulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: GO:0051445 is_a: CCO:P0000346 ! regulation of cell cycle relationship: regulates CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000340 name: positive regulation of meiotic cell cycle namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "activation of progression through meiotic cell cycle" NARROW [] synonym: "positive regulation of meiotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through meiotic cell cycle" NARROW [] synonym: "up regulation of progression through meiotic cell cycle" EXACT [] synonym: "up-regulation of progression through meiotic cell cycle" EXACT [] synonym: "upregulation of progression through meiotic cell cycle" EXACT [] xref: GO:0051446 is_a: CCO:P0000247 ! positive regulation of cell cycle is_a: CCO:P0000339 ! regulation of meiotic cell cycle relationship: positively_regulates CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000341 name: negative regulation of meiotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "down regulation of progression through meiotic cell cycle" EXACT [] synonym: "down-regulation of progression through meiotic cell cycle" EXACT [] synonym: "downregulation of progression through meiotic cell cycle" EXACT [] synonym: "inhibition of progression through meiotic cell cycle" NARROW [] synonym: "negative regulation of meiotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] xref: GO:0051447 is_a: CCO:P0000246 ! negative regulation of cell cycle is_a: CCO:P0000339 ! regulation of meiotic cell cycle relationship: negatively_regulates CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000342 name: attachment of spindle microtubules to kinetochore during meiosis I namespace: biological_process def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs." [GOC:ai, GOC:clt] comment: Note that the synonym 'monopolar attachment' refers to the normal attachment of sister chromosomes to the spindle in meiosis I, and not to the aberrant attachment of sister kinetochores to a single pole in mitosis. synonym: "monopolar attachment" EXACT [] synonym: "sister kinetochore monoorientation" EXACT [] xref: GO:0051455 is_a: CCO:P0000311 ! attachment of spindle microtubules to kinetochore during meiotic chromosome segregation relationship: part_of CCO:P0000239 ! homologous chromosome segregation [Term] id: CCO:P0000343 name: attachment of spindle microtubules to kinetochore during meiosis II namespace: biological_process def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs." [GOC:ai, GOC:clt] xref: GO:0051456 is_a: CCO:P0000311 ! attachment of spindle microtubules to kinetochore during meiotic chromosome segregation relationship: part_of CCO:P0000240 ! meiotic sister chromatid segregation [Term] id: CCO:P0000344 name: activation of anaphase-promoting complex during meiotic cell cycle namespace: biological_process def: "Any process that initiates the ubiquitin ligase activity of the anaphase-promoting complex during the meiotic cell cycle." [GOC:dph, GOC:mah, GOC:tb, PMID:10871297] synonym: "activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle" EXACT [] synonym: "activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle" EXACT [] synonym: "activation of ubiquitin ligase activity of APC during meiotic cell cycle" EXACT [] synonym: "anaphase promoting complex activation during meiotic cell cycle" EXACT [] synonym: "anaphase-promoting complex activation during meiotic cell cycle" EXACT [] synonym: "APC activation during meiotic cell cycle" EXACT [] synonym: "meiotic anaphase promoting complex activation" EXACT [] synonym: "meiotic anaphase promoting complex activator" NARROW [] synonym: "meiotic anaphase-promoting complex activator" NARROW [] synonym: "meiotic APC activation" EXACT [] synonym: "meiotic APC activator" NARROW [] xref: GO:0051487 is_a: CCO:P0000337 ! positive regulation of ubiquitin-protein ligase activity during meiotic cell cycle [Term] id: CCO:P0000345 name: meiotic recombination checkpoint namespace: biological_process def: "A checkpoint during late prophase I (pachytene) which prevents segregation of homologous chromosomes until recombination is completed and ensures proper distribution of the genetic material to the gametes." [PMID:14718568] synonym: "pachytene checkpoint" EXACT [] xref: GO:0051598 is_a: CCO:P0000219 ! meiotic cell cycle checkpoint is_a: CCO:P0000248 ! negative regulation of meiosis relationship: part_of CCO:P0000119 ! meiotic prophase I [Term] id: CCO:P0000346 name: regulation of cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb] subset: gosubset_prok synonym: "cell cycle control" EXACT [] synonym: "cell cycle modulation" EXACT [] synonym: "cell cycle regulation" EXACT [] synonym: "cell cycle regulator" RELATED [] synonym: "control of cell cycle progression" EXACT [] synonym: "modulation of cell cycle progression" EXACT [] synonym: "regulation of cell cycle progression" EXACT [] synonym: "regulation of progression through cell cycle" EXACT [] synonym: "tumor suppressor" RELATED [] xref: GO:0000074 xref: GO:0051726 xref: Reactome:156678 xref: Reactome:156699 xref: Reactome:156711 xref: Reactome:162657 xref: Reactome:204139 xref: Reactome:209045 xref: Reactome:209050 xref: Reactome:211608 xref: Reactome:213123 xref: Reactome:218715 xref: Reactome:218726 xref: Reactome:221382 xref: Reactome:222877 xref: Reactome:227596 xref: Reactome:230018 xref: Reactome:235842 xref: Reactome:235853 xref: Reactome:238231 xref: Reactome:239383 xref: Reactome:243028 xref: Reactome:243033 xref: Reactome:244651 xref: Reactome:245640 xref: Reactome:248176 xref: Reactome:248181 xref: Reactome:249585 xref: Reactome:250281 xref: Reactome:251600 xref: Reactome:252387 xref: Reactome:253031 xref: Reactome:254679 xref: Reactome:255542 xref: Reactome:256281 xref: Reactome:257921 xref: Reactome:258917 xref: Reactome:259656 xref: Reactome:261512 xref: Reactome:262291 xref: Reactome:264389 xref: Reactome:265239 xref: Reactome:267430 xref: Reactome:267435 xref: Reactome:268364 xref: Reactome:280849 xref: Reactome:282764 xref: Reactome:285431 xref: Reactome:285436 xref: Reactome:286566 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0001994 ! CABL1_HUMAN relationship: has_participant CCO:B0002010 ! MADD_HUMAN relationship: has_participant CCO:B0002054 ! UHRF2_HUMAN relationship: has_participant CCO:B0002097 ! CABL2_HUMAN relationship: regulates CCO:P0000066 ! cell cycle [Term] id: CCO:P0000347 name: cell cycle switching, meiotic to mitotic cell cycle namespace: biological_process def: "The process by which a cell switches cell cycle mode from meiotic to mitotic division." [GOC:ai] synonym: "cell cycle switching, meiotis to mitosis" NARROW [] synonym: "conversion to mitosis" NARROW [] synonym: "conversion to mitotic cell cycle" EXACT [] synonym: "entry into mitosis" NARROW [] synonym: "entry into mitotic cell cycle" EXACT [] synonym: "initiation of mitosis" NARROW [] synonym: "initiation of mitotic cell cycle" EXACT [] synonym: "mitotic entry" NARROW [] xref: GO:0051727 is_a: CCO:P0000361 ! cell cycle switching [Term] id: CCO:P0000348 name: cell cycle switching, mitotic to meiotic cell cycle namespace: biological_process def: "The process by which a cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai] synonym: "cell cycle switching, mitotis to meiosis" NARROW [] synonym: "conversion to meiosis" NARROW [] synonym: "conversion to meiotic cell cycle" EXACT [] synonym: "entry into meiosis" NARROW [] synonym: "entry into meiotic cell cycle" EXACT [] synonym: "initiation of meiosis" NARROW [] synonym: "initiation of meiotic cell cycle" EXACT [] synonym: "meiotic entry" NARROW [] xref: GO:0042061 xref: GO:0051728 is_a: CCO:P0000361 ! cell cycle switching [Term] id: CCO:P0000349 name: germline cell cycle switching, mitotic to meiotic cell cycle namespace: biological_process def: "The process by which a germline cell switches cell cycle mode from mitotic to meiotic division." [GOC:ai] synonym: "germline cell cycle switching, mitotis to meiosis" NARROW [] synonym: "germline conversion to meiosis" NARROW [] synonym: "germline conversion to meiotic cell cycle" EXACT [] synonym: "germline entry into meiosis" NARROW [] synonym: "germline entry into meiotic cell cycle" EXACT [] synonym: "germline initiation of meiosis" NARROW [] synonym: "germline initiation of meiotic cell cycle" EXACT [] synonym: "germline meiotic entry" NARROW [] xref: GO:0051729 is_a: CCO:P0000348 ! cell cycle switching, mitotic to meiotic cell cycle [Term] id: CCO:P0000350 name: meiotic sister chromatid cohesion, centromeric namespace: biological_process def: "The cell cycle process whereby centromeres of sister chromatids are joined during meiosis." [PMID:14730319, PMID:16325576] synonym: "meiotic sister chromatid cohesion at centromere" EXACT [] synonym: "sister chromatid cohesion at centromere at meiosis I" EXACT [] xref: GO:0051754 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000289 ! meiotic sister chromatid cohesion [Term] id: CCO:P0000351 name: meiotic sister chromatid arm separation namespace: biological_process def: "The cell cycle process whereby sister chromatid arms are physically detached from each other during meiosis." [GOC:ai] xref: GO:0051755 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000118 ! meiosis I relationship: part_of CCO:P0000353 ! meiotic sister chromatid separation [Term] id: CCO:P0000352 name: meiotic sister chromatid centromere separation namespace: biological_process def: "The cell cycle process whereby the centromeres of sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576] xref: GO:0051756 is_a: CCO:P0000390 ! centromere separation relationship: part_of CCO:P0000240 ! meiotic sister chromatid segregation relationship: part_of CCO:P0000353 ! meiotic sister chromatid separation [Term] id: CCO:P0000353 name: meiotic sister chromatid separation namespace: biological_process def: "The process by which sister chromatids are physically detached from each other during meiosis." [GOC:ai, PMID:14730319, PMID:16325576] xref: GO:0051757 is_a: CCO:P0000305 ! meiotic chromosome separation [Term] id: CCO:P0000354 name: homologous chromosome movement towards spindle pole during meiosis I namespace: biological_process def: "The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I." [GOC:ai] synonym: "meiosis I, homologous chromosome movement towards spindle pole" EXACT [] xref: GO:0051758 is_a: CCO:P0000155 ! meiotic chromosome movement towards spindle pole relationship: part_of CCO:P0000239 ! homologous chromosome segregation [Term] id: CCO:P0000355 name: sister chromosome movement towards spindle pole during meiosis II namespace: biological_process def: "The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II." [GOC:ai] synonym: "meiosis II, sister chromosome movement towards spindle pole" EXACT [] xref: GO:0051759 is_a: CCO:P0000155 ! meiotic chromosome movement towards spindle pole relationship: part_of CCO:P0000240 ! meiotic sister chromatid segregation [Term] id: CCO:P0000356 name: meiotic sister chromatid cohesion, arms namespace: biological_process def: "The cell cycle process whereby the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis." [PMID:14730319, PMID:16325576] synonym: "meiotic sister chromatid cohesion along arms" EXACT [] synonym: "sister chromatid cohesion along arms at meiosis I" EXACT [] xref: GO:0051760 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000289 ! meiotic sister chromatid cohesion [Term] id: CCO:P0000357 name: lateral element assembly namespace: biological_process def: "The cell cycle process whereby lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements." [PMID:11463847] xref: GO:0051878 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000121 ! synaptonemal complex assembly [Term] id: CCO:P0000358 name: generative cell mitosis namespace: biological_process def: "The process whereby the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells." [GOC:mtg_plant] xref: GO:0055047 is_a: CCO:P0000081 ! mitosis [Term] id: CCO:P0000359 name: viral process regulating host cell cycle namespace: biological_process def: "Any viral process that modulates the rate or extent of progression through the cell cycle." [GOC:dph] xref: GO:0060153 is_a: CCO:P0000346 ! regulation of cell cycle [Term] id: CCO:P0000360 name: cellular process regulating host cell cycle in response to virus namespace: biological_process def: "Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus." [GOC:dph] xref: GO:0060154 is_a: CCO:P0000346 ! regulation of cell cycle [Term] id: CCO:P0000361 name: cell cycle switching namespace: biological_process def: "The process by which a cell switches cell cycle mode." [GOC:dph, GOC:kmv, GOC:tb] xref: GO:0060184 is_a: CCO:P0000159 ! cell cycle process [Term] id: CCO:P0000362 name: plant-type spore development namespace: biological_process def: "The process whose specific outcome is the progression of the spore over time, from its formation to the mature structure. The spore gives rise to gametophytes." [GOC:jic, http://www.m-w.com] synonym: "plant spore development" EXACT [] synonym: "spore development (sensu Magnoliophyta)" EXACT [] xref: GO:0048236 is_a: CCO:P0000316 ! meiotic cell cycle [Term] id: CCO:P0000363 name: negative regulation of cell cycle arrest in response to nitrogen starvation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation." [GOC:dph, GOC:tb] xref: GO:0010503 is_a: CCO:P0000364 ! regulation of cell cycle arrest in response to nitrogen starvation is_a: CCO:P0000960 ! negative regulation of cellular response to nitrogen starvation relationship: negatively_regulates CCO:P0000166 ! cell cycle arrest in response to nitrogen starvation [Term] id: CCO:P0000364 name: regulation of cell cycle arrest in response to nitrogen starvation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation." [GOC:dph, GOC:tb] xref: GO:0010504 is_a: CCO:P0000382 ! regulation of cell cycle process relationship: regulates CCO:P0000166 ! cell cycle arrest in response to nitrogen starvation [Term] id: CCO:P0000365 name: positive regulation of cell cycle arrest in response to nitrogen starvation namespace: biological_process def: "Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation." [GOC:dph, GOC:tb] xref: GO:0010505 is_a: CCO:P0000364 ! regulation of cell cycle arrest in response to nitrogen starvation is_a: CCO:P0002852 ! positive regulation of cellular process relationship: positively_regulates CCO:P0000166 ! cell cycle arrest in response to nitrogen starvation [Term] id: CCO:P0000366 name: establishment of sister chromatid cohesion namespace: biological_process def: "The process by which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase." [GOC:mah, PMID:14623866] xref: GO:0034085 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000076 ! sister chromatid cohesion [Term] id: CCO:P0000367 name: maintenance of sister chromatid cohesion namespace: biological_process def: "The process by which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate." [GOC:mah, PMID:14623866] xref: GO:0034086 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000076 ! sister chromatid cohesion [Term] id: CCO:P0000368 name: establishment of mitotic sister chromatid cohesion namespace: biological_process def: "The process by which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle." [GOC:mah] xref: GO:0034087 is_a: CCO:P0000366 ! establishment of sister chromatid cohesion relationship: part_of CCO:P0000078 ! mitotic sister chromatid cohesion [Term] id: CCO:P0000369 name: maintenance of mitotic sister chromatid cohesion namespace: biological_process def: "The process by which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle." [GOC:mah] synonym: "mitotic cohesion stability" RELATED [] xref: GO:0034088 is_a: CCO:P0000367 ! maintenance of sister chromatid cohesion relationship: part_of CCO:P0000078 ! mitotic sister chromatid cohesion [Term] id: CCO:P0000370 name: establishment of meiotic sister chromatid cohesion namespace: biological_process def: "The process by which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle." [GOC:mah] xref: GO:0034089 is_a: CCO:P0000366 ! establishment of sister chromatid cohesion relationship: part_of CCO:P0000289 ! meiotic sister chromatid cohesion [Term] id: CCO:P0000371 name: maintenance of meiotic sister chromatid cohesion namespace: biological_process def: "The process by which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle." [GOC:mah] xref: GO:0034090 is_a: CCO:P0000367 ! maintenance of sister chromatid cohesion relationship: part_of CCO:P0000289 ! meiotic sister chromatid cohesion [Term] id: CCO:P0000372 name: regulation of maintenance of sister chromatid cohesion namespace: biological_process def: "Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained." [GOC:mah, GOC:vw] xref: GO:0034091 is_a: CCO:P0000077 ! regulation of sister chromatid cohesion relationship: regulates CCO:P0000367 ! maintenance of sister chromatid cohesion [Term] id: CCO:P0000373 name: negative regulation of maintenance of sister chromatid cohesion namespace: biological_process def: "Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained." [GOC:mah, GOC:vw] xref: GO:0034092 is_a: CCO:P0000254 ! negative regulation of sister chromatid cohesion is_a: CCO:P0000372 ! regulation of maintenance of sister chromatid cohesion relationship: negatively_regulates CCO:P0000367 ! maintenance of sister chromatid cohesion [Term] id: CCO:P0000374 name: positive regulation of maintenance of sister chromatid cohesion namespace: biological_process def: "Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained." [GOC:mah, GOC:vw] xref: GO:0034093 is_a: CCO:P0000255 ! positive regulation of sister chromatid cohesion is_a: CCO:P0000372 ! regulation of maintenance of sister chromatid cohesion relationship: positively_regulates CCO:P0000367 ! maintenance of sister chromatid cohesion [Term] id: CCO:P0000375 name: regulation of maintenance of meiotic sister chromatid cohesion namespace: biological_process def: "Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle." [GOC:mah, GOC:vw] xref: GO:0034094 is_a: CCO:P0000372 ! regulation of maintenance of sister chromatid cohesion relationship: regulates CCO:P0000371 ! maintenance of meiotic sister chromatid cohesion [Term] id: CCO:P0000376 name: negative regulation of maintenance of meiotic sister chromatid cohesion namespace: biological_process def: "Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle." [GOC:mah, GOC:vw] xref: GO:0034095 is_a: CCO:P0000373 ! negative regulation of maintenance of sister chromatid cohesion is_a: CCO:P0000375 ! regulation of maintenance of meiotic sister chromatid cohesion relationship: negatively_regulates CCO:P0000371 ! maintenance of meiotic sister chromatid cohesion [Term] id: CCO:P0000377 name: positive regulation of maintenance of meiotic sister chromatid cohesion namespace: biological_process def: "Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle." [GOC:mah, GOC:vw] xref: GO:0034096 is_a: CCO:P0000374 ! positive regulation of maintenance of sister chromatid cohesion is_a: CCO:P0000375 ! regulation of maintenance of meiotic sister chromatid cohesion relationship: positively_regulates CCO:P0000371 ! maintenance of meiotic sister chromatid cohesion [Term] id: CCO:P0000378 name: regulation of maintenance of mitotic sister chromatid cohesion namespace: biological_process def: "Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle." [GOC:mah, GOC:vw] xref: GO:0034182 is_a: CCO:P0000372 ! regulation of maintenance of sister chromatid cohesion relationship: regulates CCO:P0000369 ! maintenance of mitotic sister chromatid cohesion [Term] id: CCO:P0000379 name: negative regulation of maintenance of mitotic sister chromatid cohesion namespace: biological_process def: "Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle." [GOC:mah, GOC:vw] xref: GO:0034183 is_a: CCO:P0000373 ! negative regulation of maintenance of sister chromatid cohesion is_a: CCO:P0000378 ! regulation of maintenance of mitotic sister chromatid cohesion relationship: negatively_regulates CCO:P0000369 ! maintenance of mitotic sister chromatid cohesion [Term] id: CCO:P0000380 name: positive regulation of maintenance of mitotic sister chromatid cohesion namespace: biological_process def: "Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle." [GOC:mah, GOC:vw] xref: GO:0034184 is_a: CCO:P0000374 ! positive regulation of maintenance of sister chromatid cohesion is_a: CCO:P0000378 ! regulation of maintenance of mitotic sister chromatid cohesion relationship: positively_regulates CCO:P0000369 ! maintenance of mitotic sister chromatid cohesion [Term] id: CCO:P0000381 name: regulation of meiotic recombination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of recombination during meiosis." [GOC:dph, GOC:tb] xref: GO:0010520 is_a: CCO:P0000226 ! regulation of meiosis is_a: CCO:P0000398 ! regulation of DNA recombination relationship: regulates CCO:P0000122 ! meiotic recombination [Term] id: CCO:P0000382 name: regulation of cell cycle process namespace: biological_process def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] xref: GO:0010564 is_a: CCO:P0002955 ! regulation of cellular process relationship: regulates CCO:P0000159 ! cell cycle process [Term] id: CCO:P0000383 name: positive regulation of DNA replication during S phase namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA replication during progression through S phase of the cell cycle." [GOC:dph, GOC:jp, GOC:tb] xref: GO:0010571 is_a: CCO:P0000216 ! regulation of DNA replication during S phase is_a: CCO:P0002528 ! positive regulation of DNA replication relationship: positively_regulates CCO:P0000214 ! DNA replication during S phase [Term] id: CCO:P0000384 name: regulation of mitotic spindle organization and biogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the microtubule spindle during a mitotic cell cycle." [GOC:dph, GOC:tb] xref: GO:0060236 is_a: CCO:P0000382 ! regulation of cell cycle process is_a: CCO:P0001703 ! regulation of microtubule-based process relationship: regulates CCO:P0000068 ! mitotic spindle organization and biogenesis [Term] id: CCO:P0000385 name: spindle organization and biogenesis namespace: biological_process def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart." [GOC:mah] synonym: "spindle organisation and biogenesis" EXACT [] xref: GO:0007051 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0001587 ! TTK_HUMAN relationship: has_participant CCO:B0002058 ! SPAG5_HUMAN relationship: part_of CCO:P0000039 ! M phase [Term] id: CCO:P0000386 name: astral microtubule organization and biogenesis namespace: biological_process def: "A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles." [GOC:mah] synonym: "astral microtubule organisation and biogenesis" EXACT [] xref: GO:0030953 is_a: CCO:P0000385 ! spindle organization and biogenesis [Term] id: CCO:P0000387 name: astral microtubule nucleation namespace: biological_process def: "The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule." [GOC:mah] xref: GO:0030954 is_a: CCO:P0000386 ! astral microtubule organization and biogenesis [Term] id: CCO:P0000388 name: negative regulation of astral microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the depolymerization of astral microtubules." [GOC:mah] synonym: "astral microtubule stabilization" EXACT [] xref: GO:0032932 is_a: CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: negatively_regulates CCO:P0000397 ! astral microtubule depolymerization [Term] id: CCO:P0000389 name: rDNA separation namespace: biological_process def: "The cell cycle process whereby rDNA repeat regions are physically detached from each other during chromosome separation." [GOC:mah] xref: GO:0034500 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000303 ! chromosome separation [Term] id: CCO:P0000390 name: centromere separation namespace: biological_process def: "The cell cycle process whereby centromeres are physically detached from each other during chromosome separation." [GOC:mah] xref: GO:0034510 is_a: CCO:P0000159 ! cell cycle process relationship: part_of CCO:P0000303 ! chromosome separation [Term] id: CCO:P0000391 name: spindle stabilization namespace: biological_process def: "Any process involved in maintaining the structure and integrity of the spindle." [GOC:go_curators] xref: GO:0043146 is_a: CCO:P0000693 ! negative regulation of microtubule depolymerization relationship: part_of CCO:P0000385 ! spindle organization and biogenesis [Term] id: CCO:P0000392 name: spindle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." [GOC:ai, GOC:mtg_sensu, GOC:rg, GOC:tb] synonym: "bipolar spindle biosynthesis" EXACT [] synonym: "bipolar spindle formation" EXACT [] synonym: "meiotic spindle assembly" NARROW [] synonym: "meiotic spindle biogenesis" NARROW [] synonym: "meiotic spindle biosynthesis" NARROW [] synonym: "meiotic spindle formation" NARROW [] synonym: "mitotic spindle assembly" NARROW [] synonym: "mitotic spindle biogenesis" NARROW [] synonym: "mitotic spindle biosynthesis" NARROW [] synonym: "mitotic spindle formation" NARROW [] synonym: "spindle assembly involved in meiosis" NARROW [] synonym: "spindle assembly involved in mitosis" NARROW [] synonym: "spindle biogenesis" EXACT [] synonym: "spindle biogenesis involved in meiosis" NARROW [] synonym: "spindle biogenesis involved in mitosis" NARROW [] synonym: "spindle biosynthesis" EXACT [] synonym: "spindle formation" EXACT [] synonym: "spindle formation involved in meiosis" NARROW [] synonym: "spindle formation involved in mitosis" NARROW [] xref: GO:0051225 xref: GO:0051226 xref: GO:0051227 is_a: CCO:P0000385 ! spindle organization and biogenesis [Term] id: CCO:P0000393 name: spindle disassembly namespace: biological_process def: "The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." [GOC:ai] synonym: "spindle breakdown" EXACT [] synonym: "spindle catabolism" EXACT [] synonym: "spindle degradation" EXACT [] xref: GO:0051230 is_a: CCO:P0000385 ! spindle organization and biogenesis [Term] id: CCO:P0000394 name: anastral spindle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins." [GOC:mtg_sensu, GOC:rg, GOC:tb, PMID:15034926] xref: GO:0055048 is_a: CCO:P0000392 ! spindle assembly [Term] id: CCO:P0000395 name: astral spindle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes." [GOC:tb] xref: GO:0055049 is_a: CCO:P0000392 ! spindle assembly [Term] id: CCO:P0000396 name: astral spindle assembly involved in male meiosis namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells." [GOC:tb] xref: GO:0055050 is_a: CCO:P0000395 ! astral spindle assembly [Term] id: CCO:P0000397 name: astral microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [GOC:dph] xref: GO:0060172 is_a: CCO:P0000386 ! astral microtubule organization and biogenesis [Term] id: CCO:P0000398 name: regulation of DNA recombination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA recombination, a process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0000018 is_a: CCO:P0003015 ! regulation of DNA metabolic process relationship: has_participant CCO:B0001657 ! IMA2_HUMAN relationship: has_participant CCO:B0020532 ! IMA1_HUMAN relationship: has_participant CCO:B0055060 ! IL7RA_HUMAN relationship: has_participant CCO:B0058717 ! SMRCD_HUMAN [Term] id: CCO:P0000399 name: regulation of mitotic recombination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA recombination during mitosis." [GOC:go_curators] synonym: "regulation of recombination within rDNA repeats" NARROW [] xref: GO:0000019 is_a: CCO:P0000398 ! regulation of DNA recombination relationship: has_participant CCO:B0001641 ! MRE11_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN [Term] id: CCO:P0000400 name: negative regulation of transcription from RNA polymerase II promoter namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators] synonym: "down regulation of transcription from RNA polymerase II promoter" EXACT [] synonym: "down-regulation of transcription from RNA polymerase II promoter" EXACT [] synonym: "downregulation of transcription from RNA polymerase II promoter" EXACT [] synonym: "inhibition of transcription from RNA polymerase II promoter" NARROW [] synonym: "negative regulation of transcription from Pol II promoter" EXACT [] xref: GO:0000122 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0001358 ! OVOL1_HUMAN relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001429 ! E2F6_HUMAN relationship: has_participant CCO:B0001445 ! HEXI1_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001536 ! WT1_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001664 ! FOSB_HUMAN relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0001717 ! ID3_HUMAN relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0002049 ! HEXI2_HUMAN relationship: has_participant CCO:B0002263 ! EID1_HUMAN relationship: has_participant CCO:B0005191 ! SATB1_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0005779 ! ENOA_HUMAN relationship: has_participant CCO:B0005981 ! TRI27_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN relationship: has_participant CCO:B0006149 ! ID2_HUMAN relationship: has_participant CCO:B0006246 ! TGIF1_HUMAN relationship: has_participant CCO:B0015399 ! MAD4_HUMAN relationship: has_participant CCO:B0016695 ! FOXE1_HUMAN relationship: has_participant CCO:B0016733 ! FOXD3_HUMAN relationship: has_participant CCO:B0020283 ! SOX15_HUMAN relationship: has_participant CCO:B0020932 ! GLIS1_HUMAN relationship: has_participant CCO:B0022559 ! SLAP2_HUMAN relationship: has_participant CCO:B0022832 ! BCL6B_HUMAN relationship: has_participant CCO:B0024873 ! NR6A1_HUMAN relationship: has_participant CCO:B0026249 ! ZMY11_HUMAN relationship: has_participant CCO:B0032499 ! MEIS2_HUMAN relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0034126 ! RARG_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0036793 ! HXA7_HUMAN relationship: has_participant CCO:B0037928 ! IRF7_HUMAN relationship: has_participant CCO:B0037929 ! IRF8_HUMAN relationship: has_participant CCO:B0040686 ! NC2A_HUMAN relationship: has_participant CCO:B0040687 ! CUX1_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0049892 ! DBPA_HUMAN relationship: has_participant CCO:B0051010 ! SPT4H_HUMAN relationship: has_participant CCO:B0054328 ! ZN593_HUMAN relationship: has_participant CCO:B0054387 ! KLF11_HUMAN relationship: has_participant CCO:B0054504 ! SNAI2_HUMAN relationship: has_participant CCO:B0054523 ! ZF161_HUMAN relationship: has_participant CCO:B0054540 ! ST18_HUMAN relationship: has_participant CCO:B0054564 ! VINEX_HUMAN relationship: has_participant CCO:B0054622 ! PROP1_HUMAN relationship: has_participant CCO:B0054635 ! ZN254_HUMAN relationship: has_participant CCO:B0054646 ! HSBP1_HUMAN relationship: has_participant CCO:B0054658 ! PRDM1_HUMAN relationship: has_participant CCO:B0054671 ! ZN189_HUMAN relationship: has_participant CCO:B0054698 ! MTA2_HUMAN relationship: has_participant CCO:B0054725 ! ZN202_HUMAN relationship: has_participant CCO:B0054751 ! ZBT7A_HUMAN relationship: has_participant CCO:B0054819 ! HAND1_HUMAN relationship: has_participant CCO:B0054965 ! GLI2_HUMAN relationship: has_participant CCO:B0055009 ! NR2C1_HUMAN relationship: has_participant CCO:B0055022 ! IRF2_HUMAN relationship: has_participant CCO:B0055083 ! ZNF8_HUMAN relationship: has_participant CCO:B0055095 ! SPI1_HUMAN relationship: has_participant CCO:B0055100 ! EGR1_HUMAN relationship: has_participant CCO:B0055111 ! FST_HUMAN relationship: has_participant CCO:B0055203 ! MSX1_HUMAN relationship: has_participant CCO:B0055317 ! ZEB1_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN relationship: has_participant CCO:B0055470 ! MECP2_HUMAN relationship: has_participant CCO:B0055478 ! ZN157_HUMAN relationship: has_participant CCO:B0055491 ! ZN136_HUMAN relationship: has_participant CCO:B0055506 ! NKX25_HUMAN relationship: has_participant CCO:B0055692 ! NC2B_HUMAN relationship: has_participant CCO:B0055722 ! PPARD_HUMAN relationship: has_participant CCO:B0055846 ! BPTF_HUMAN relationship: has_participant CCO:B0055847 ! PO4F2_HUMAN relationship: has_participant CCO:B0055863 ! NFX1_HUMAN relationship: has_participant CCO:B0055875 ! KLF10_HUMAN relationship: has_participant CCO:B0055901 ! ZN177_HUMAN relationship: has_participant CCO:B0055921 ! OLIG2_HUMAN relationship: has_participant CCO:B0055969 ! SIM2_HUMAN relationship: has_participant CCO:B0055986 ! HES1_HUMAN relationship: has_participant CCO:B0055997 ! ZN345_HUMAN relationship: has_participant CCO:B0056036 ! SUZ12_HUMAN relationship: has_participant CCO:B0056048 ! TCAL1_HUMAN relationship: has_participant CCO:B0056067 ! NR0B2_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0056095 ! TWST1_HUMAN relationship: has_participant CCO:B0056096 ! ZN174_HUMAN relationship: has_participant CCO:B0056097 ! ALX1_HUMAN relationship: has_participant CCO:B0056118 ! ZFHX3_HUMAN relationship: has_participant CCO:B0057269 ! JAZF1_HUMAN relationship: has_participant CCO:B0057465 ! RYBP_HUMAN relationship: has_participant CCO:B0058162 ! PF21A_HUMAN relationship: has_participant CCO:B0058234 ! PAWR_HUMAN relationship: has_participant CCO:B0058246 ! LCOR_HUMAN relationship: has_participant CCO:B0058266 ! NSD1_HUMAN relationship: has_participant CCO:B0058376 ! NR1H4_HUMAN relationship: has_participant CCO:B0058428 ! ZN238_HUMAN relationship: has_participant CCO:B0058451 ! NPAS1_HUMAN relationship: has_participant CCO:B0058475 ! TCF25_HUMAN relationship: has_participant CCO:B0058569 ! HDAC8_HUMAN relationship: has_participant CCO:B0058576 ! HES7_HUMAN relationship: has_participant CCO:B0058638 ! WWTR1_HUMAN relationship: has_participant CCO:B0058659 ! GZF1_HUMAN relationship: has_participant CCO:B0058998 ! TF2L1_HUMAN relationship: has_participant CCO:B0059018 ! LMCD1_HUMAN relationship: has_participant CCO:B0059141 ! DDX20_HUMAN relationship: has_participant CCO:B0059166 ! VAX2_HUMAN relationship: has_participant CCO:B0059175 ! LEF1_HUMAN relationship: has_participant CCO:B0059285 ! ZN148_HUMAN relationship: has_participant CCO:B0059321 ! ZN281_HUMAN relationship: has_participant CCO:B0059324 ! ZBT32_HUMAN relationship: has_participant CCO:B0059366 ! KLF12_HUMAN [Term] id: CCO:P0000401 name: two-component signal transduction system (phosphorelay) namespace: biological_process def: "A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins." [PMID:9191038] subset: gosubset_prok synonym: "histidyl-aspartyl phosphorelay" EXACT [] xref: GO:0000160 is_a: CCO:P0000708 ! signal transduction relationship: has_participant CCO:B0054571 ! PDE8A_HUMAN relationship: has_participant CCO:B0054741 ! KCNH1_HUMAN relationship: has_participant CCO:B0054742 ! PDE8B_HUMAN relationship: has_participant CCO:B0055844 ! KCNH2_HUMAN relationship: has_participant CCO:B0057288 ! Q86XI1_HUMAN relationship: has_participant CCO:B0057570 ! KCNH5_HUMAN relationship: has_participant CCO:B0058265 ! KCNH8_HUMAN relationship: has_participant CCO:B0058403 ! MMS19_HUMAN relationship: has_participant CCO:B0059042 ! Q9P1T1_HUMAN relationship: has_participant CCO:B0059223 ! KCNH3_HUMAN relationship: has_participant CCO:B0059273 ! KCNH4_HUMAN [Term] id: CCO:P0000402 name: MAPKKK cascade during osmolarity sensing namespace: biological_process def: "MAPKKK cascade involved in signal transduction in response to change in osmotic conditions." [PMID:9561267] synonym: "osmolarity sensing, MAPKKK cascade" EXACT [] xref: GO:0000161 is_a: CCO:P0000403 ! MAPKKK cascade relationship: part_of CCO:P0000763 ! osmosensory signaling pathway [Term] id: CCO:P0000403 name: MAPKKK cascade namespace: biological_process def: "Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways." [GOC:mah, PMID:9561267] synonym: "ERK/MAPK cascade" EXACT [] synonym: "MAP kinase cascade" EXACT [] synonym: "MAP kinase kinase kinase cascade" EXACT [] synonym: "MAPK cascade" EXACT [] synonym: "MAPK signaling" RELATED [] synonym: "MAPK signalling" RELATED [] synonym: "MAPKKK cascade during sporulation (sensu Fungi)" NARROW [] synonym: "MAPKKK cascade during sporulation (sensu Saccharomyces)" NARROW [] xref: GO:0000165 xref: Reactome:109869 xref: Reactome:211967 xref: Reactome:221732 xref: Reactome:230313 xref: Reactome:238351 xref: Reactome:244909 xref: Reactome:249802 xref: Reactome:252619 xref: Reactome:255804 xref: Reactome:259197 xref: Reactome:262555 xref: Reactome:268509 xref: Reactome:274234 xref: Reactome:280703 xref: Reactome:286727 is_a: CCO:P0000767 ! protein kinase cascade relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001744 ! DUS4_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN relationship: has_participant CCO:B0005868 ! FGFR1_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0017676 ! FGF13_HUMAN relationship: has_participant CCO:B0019510 ! TAOK3_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0055014 ! SCG2_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN relationship: has_participant CCO:B0055904 ! JIP2_HUMAN relationship: has_participant CCO:B0056114 ! SMAD1_HUMAN relationship: has_participant CCO:B0056531 ! LRRK2_HUMAN relationship: has_participant CCO:B0057337 ! GRP3_HUMAN relationship: has_participant CCO:B0057957 ! DOK4_HUMAN relationship: has_participant CCO:B0058383 ! KKCC2_HUMAN relationship: has_participant CCO:B0058453 ! NRTN_HUMAN relationship: has_participant CCO:B0058573 ! SHAN3_HUMAN relationship: has_participant CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:P0000404 name: activation of MAPKKK activity during osmolarity sensing namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during osmolarity sensing." [PMID:9561267] synonym: "activation of MAP kinase kinase kinase activity during osmolarity sensing" EXACT [] synonym: "osmolarity sensing, activation of MAP kinase kinase kinase activity" EXACT [] synonym: "osmolarity sensing, activation of MAPKKK activity" EXACT [] xref: GO:0000167 is_a: CCO:P0000409 ! activation of MAPKKK activity relationship: part_of CCO:P0000402 ! MAPKKK cascade during osmolarity sensing [Term] id: CCO:P0000405 name: activation of MAPKK activity during osmolarity sensing namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase during osmolarity sensing." [PMID:9561267] synonym: "activation of MAP kinase kinase activity during osmolarity sensing" EXACT [] synonym: "activation of Pbs2 kinase" NARROW [] synonym: "osmolarity sensing, activation of MAP kinase kinase activity" EXACT [] synonym: "osmolarity sensing, activation of MAPKK activity" EXACT [] xref: GO:0000168 xref: GO:0007233 is_a: CCO:P0000410 ! activation of MAPKK activity relationship: part_of CCO:P0000402 ! MAPKKK cascade during osmolarity sensing [Term] id: CCO:P0000406 name: activation of MAPK activity during osmolarity sensing namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme MAP kinase activity during osmolarity sensing." [PMID:9561267] synonym: "osmolarity sensing, activation of MAPK activity" EXACT [] xref: GO:0000169 is_a: CCO:P0000411 ! activation of MAPK activity relationship: part_of CCO:P0000402 ! MAPKKK cascade during osmolarity sensing [Term] id: CCO:P0000407 name: inactivation of MAPK activity during osmolarity sensing namespace: biological_process def: "Any process that terminates the activity of the active enzyme MAP kinase during osmolarity sensing." [PMID:9561267] synonym: "osmolarity sensing, inactivation of MAPK" EXACT [] synonym: "osmolarity sensing, termination of MAPK activity" EXACT [] synonym: "termination of MAPK activity during osmolarity sensing" EXACT [] xref: GO:0000173 is_a: CCO:P0000412 ! inactivation of MAPK activity relationship: has_participant CCO:B0005271 ! MBIP1_HUMAN relationship: part_of CCO:P0000402 ! MAPKKK cascade during osmolarity sensing [Term] id: CCO:P0000408 name: chromatin silencing at rDNA namespace: biological_process def: "Repression of transcription of ribosomal DNA by the formation of heterochromatin." [PMID:10219245] synonym: "chromatin silencing at ribosomal DNA" EXACT [] synonym: "heterochromatic silencing at rDNA" EXACT [] xref: GO:0000183 is_a: CCO:P0000648 ! chromatin silencing relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN [Term] id: CCO:P0000409 name: activation of MAPKKK activity namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase." [PMID:9561267] synonym: "activation of MAP kinase kinase kinase" EXACT [] synonym: "activation of MAPKKK during sporulation (sensu Fungi)" NARROW [] synonym: "activation of MAPKKK during sporulation (sensu Saccharomyces)" NARROW [] synonym: "positive regulation of MAP kinase kinase kinase activity" BROAD [] synonym: "positive regulation of MAPKKK activity" BROAD [] xref: GO:0000185 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001424 ! GA45B_HUMAN relationship: has_participant CCO:B0005411 ! GA45G_HUMAN relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0056926 ! TRAF7_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN relationship: part_of CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0000410 name: activation of MAPKK activity namespace: biological_process def: "The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK." [PMID:9561267] synonym: "activation of MAP kinase kinase activity" EXACT [] synonym: "activation of MAP/ERK kinase kinase" EXACT [] synonym: "activation of MAPKK during sporulation (sensu Fungi)" NARROW [] synonym: "activation of MAPKK during sporulation (sensu Saccharomyces)" NARROW [] synonym: "positive regulation of MAPKK activity" BROAD [] xref: GO:0000186 xref: GO:0007255 xref: Reactome:110049 xref: Reactome:211601 xref: Reactome:221376 xref: Reactome:230014 xref: Reactome:238032 xref: Reactome:244648 xref: Reactome:249583 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001424 ! GA45B_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0005915 ! M3K4_HUMAN relationship: has_participant CCO:B0018761 ! M3K13_HUMAN relationship: has_participant CCO:B0019513 ! TAOK2_HUMAN relationship: has_participant CCO:B0056152 ! CART_HUMAN relationship: has_participant CCO:B0059131 ! MK1I1_HUMAN relationship: part_of CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0000411 name: activation of MAPK activity namespace: biological_process def: "The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK." [PMID:9561267] synonym: "activation of MAP kinase" EXACT [] synonym: "activation of MAPK during sporulation (sensu Fungi)" NARROW [] synonym: "activation of MAPK during sporulation (sensu Saccharomyces)" NARROW [] synonym: "MAPK activation" EXACT [] xref: GO:0000187 xref: Reactome:112409 xref: Reactome:212039 xref: Reactome:221803 xref: Reactome:230377 xref: Reactome:238416 xref: Reactome:244963 xref: Reactome:249842 xref: Reactome:252574 xref: Reactome:255755 xref: Reactome:259149 xref: Reactome:262506 xref: Reactome:268461 xref: Reactome:274183 xref: Reactome:280656 xref: Reactome:286675 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001610 ! PK3CB_HUMAN relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0001683 ! PROK1_HUMAN relationship: has_participant CCO:B0001820 ! M3K11_HUMAN relationship: has_participant CCO:B0001879 ! AVPI1_HUMAN relationship: has_participant CCO:B0002010 ! MADD_HUMAN relationship: has_participant CCO:B0005438 ! MET_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005870 ! TGFA_HUMAN relationship: has_participant CCO:B0005872 ! AAPK1_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN relationship: has_participant CCO:B0006262 ! CD81_HUMAN relationship: has_participant CCO:B0017123 ! PROK2_HUMAN relationship: has_participant CCO:B0027200 ! FPR1_HUMAN relationship: has_participant CCO:B0033014 ! SODC_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0037429 ! CNRG_HUMAN relationship: has_participant CCO:B0037430 ! CNCG_HUMAN relationship: has_participant CCO:B0042225 ! GRM4_HUMAN relationship: has_participant CCO:B0049019 ! IGHM_HUMAN relationship: has_participant CCO:B0054727 ! S1PR2_HUMAN relationship: has_participant CCO:B0054830 ! CO5_HUMAN relationship: has_participant CCO:B0054883 ! PA21B_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054937 ! ADA2A_HUMAN relationship: has_participant CCO:B0055104 ! ADA2C_HUMAN relationship: has_participant CCO:B0055137 ! C5AR_HUMAN relationship: has_participant CCO:B0055211 ! AA2BR_HUMAN relationship: has_participant CCO:B0055310 ! ACHA7_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN relationship: has_participant CCO:B0055632 ! GBG3_HUMAN relationship: has_participant CCO:B0057975 ! FRS2_HUMAN relationship: has_participant CCO:B0058555 ! C1QT2_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059318 ! M3K2_HUMAN relationship: part_of CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0000412 name: inactivation of MAPK activity namespace: biological_process def: "Any process that terminates the activity of the active enzyme MAP kinase." [PMID:9561267] synonym: "inactivation of MAPK during sporulation (sensu Fungi)" NARROW [] synonym: "inactivation of MAPK during sporulation (sensu Saccharomyces)" NARROW [] synonym: "termination of MAPK activity" EXACT [] xref: GO:0000188 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0001740 ! CSN1_HUMAN relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0001824 ! DUS6_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0020771 ! RGS3_HUMAN relationship: has_participant CCO:B0021669 ! DUS2_HUMAN relationship: has_participant CCO:B0026710 ! RGS4_HUMAN relationship: has_participant CCO:B0037152 ! DUS16_HUMAN relationship: has_participant CCO:B0037159 ! DUS8_HUMAN relationship: has_participant CCO:B0057194 ! SPRE2_HUMAN relationship: has_participant CCO:B0057195 ! SPRE1_HUMAN relationship: has_participant CCO:B0057364 ! LAX1_HUMAN relationship: has_participant CCO:B0057969 ! DUS19_HUMAN relationship: has_participant CCO:B0058464 ! DUS9_HUMAN relationship: has_participant CCO:B0058906 ! DUS22_HUMAN relationship: part_of CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0000413 name: nuclear translocation of MAPK namespace: biological_process def: "The directed movement of a MAP kinase to the nucleus upon activation." [PMID:9561267] xref: GO:0000189 xref: Reactome:109867 xref: Reactome:109868 xref: Reactome:112353 xref: Reactome:209891 xref: Reactome:209896 xref: Reactome:228348 xref: Reactome:228351 xref: Reactome:236568 xref: Reactome:236573 xref: Reactome:243599 xref: Reactome:243605 xref: Reactome:248698 xref: Reactome:248703 xref: Reactome:251790 xref: Reactome:251793 xref: Reactome:254938 xref: Reactome:254943 xref: Reactome:258208 xref: Reactome:258211 xref: Reactome:261726 xref: Reactome:261729 xref: Reactome:267714 xref: Reactome:267717 xref: Reactome:273179 xref: Reactome:273186 xref: Reactome:279660 xref: Reactome:279666 xref: Reactome:285768 xref: Reactome:285771 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0000414 name: MAPKKK cascade during cell wall biogenesis namespace: biological_process def: "Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase that occurs during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267] synonym: "cell wall biogenesis, MAPKKK cascade" EXACT [] xref: GO:0000196 is_a: CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0000415 name: activation of MAPKKK activity during cell wall biogenesis namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267] synonym: "activation of MAP kinase kinase kinase activity during cell wall biogenesis" EXACT [] synonym: "cell wall biogenesis, activation of MAP kinase kinase kinase activity" EXACT [] synonym: "cell wall biogenesis, activation of MAPKKK activity" EXACT [] xref: GO:0000197 is_a: CCO:P0000409 ! activation of MAPKKK activity relationship: part_of CCO:P0000414 ! MAPKKK cascade during cell wall biogenesis [Term] id: CCO:P0000416 name: activation of MAPKK activity during cell wall biogenesis namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme MAP kinase kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267] synonym: "activation of MAP kinase kinase activity during cell wall biogenesis" EXACT [] synonym: "cell wall biogenesis, activation of MAP kinase kinase activity" EXACT [] synonym: "cell wall biogenesis, activation of MAPKK activity" EXACT [] xref: GO:0000198 is_a: CCO:P0000410 ! activation of MAPKK activity relationship: part_of CCO:P0000414 ! MAPKKK cascade during cell wall biogenesis [Term] id: CCO:P0000417 name: activation of MAPK activity during cell wall biogenesis namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267] synonym: "cell wall biogenesis, activation of MAPK activity" EXACT [] xref: GO:0000199 is_a: CCO:P0000411 ! activation of MAPK activity relationship: part_of CCO:P0000414 ! MAPKKK cascade during cell wall biogenesis [Term] id: CCO:P0000418 name: inactivation of MAPK activity during cell wall biogenesis namespace: biological_process def: "Any process that terminates the activity of the active enzyme MAP kinase during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267] synonym: "cell wall biogenesis, inactivation of MAPK activity" EXACT [] synonym: "cell wall biogenesis, termination of MAPK activity" EXACT [] synonym: "termination of MAPK activity during cell wall biogenesis" EXACT [] xref: GO:0000200 is_a: CCO:P0000412 ! inactivation of MAPK activity relationship: part_of CCO:P0000414 ! MAPKKK cascade during cell wall biogenesis [Term] id: CCO:P0000419 name: nuclear translocation of MAPK during cell wall biogenesis namespace: biological_process def: "The directed movement of a MAP kinase to the nucleus during cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells." [PMID:9561267] synonym: "cell wall biogenesis, nuclear translocation of MAPK" EXACT [] xref: GO:0000201 is_a: CCO:P0000413 ! nuclear translocation of MAPK relationship: part_of CCO:P0000414 ! MAPKKK cascade during cell wall biogenesis [Term] id: CCO:P0000420 name: nuclear translocation of MAPK during osmolarity sensing namespace: biological_process def: "The directed movement of a MAP kinase to the nucleus during osmolarity sensing." [PMID:9561267] synonym: "osmolarity sensing, nuclear translocation of MAPK" EXACT [] xref: GO:0000208 is_a: CCO:P0000413 ! nuclear translocation of MAPK relationship: part_of CCO:P0000402 ! MAPKKK cascade during osmolarity sensing [Term] id: CCO:P0000421 name: cellular bud site selection namespace: biological_process def: "The specification of the site where a daughter cell will form, in organisms that reproduce by budding." [GOC:mah] comment: Note that this term was split from 'bud site selection/establishment of cell polarity (sensu Saccharomyces) ; GO:0007115' (sibling term 'establishment of cell polarity (sensu Saccharomyces) ; GO:0000283'). synonym: "bud site selection/establishment of cell polarity (sensu Saccharomyces)" BROAD [] xref: GO:0000282 is_a: CCO:P0000696 ! cytokinesis, site selection [Term] id: CCO:P0000422 name: negative regulation of transposition, DNA-mediated namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA transposition." [GOC:dph, GOC:krc, GOC:tb] subset: gosubset_prok synonym: "down regulation of DNA transposition" EXACT [] synonym: "down-regulation of DNA transposition" EXACT [] synonym: "downregulation of DNA transposition" EXACT [] synonym: "inhibition of DNA transposition" NARROW [] synonym: "negative regulation of DNA transposition" EXACT [GOC:dph] xref: GO:0000335 is_a: CCO:P0000424 ! regulation of transposition, DNA-mediated is_a: CCO:P0000965 ! negative regulation of transposition [Term] id: CCO:P0000423 name: positive regulation of transposition, DNA-mediated namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA transposition." [GOC:dph, GOC:krc] subset: gosubset_prok synonym: "activation of DNA transposition" NARROW [] synonym: "positive regulation of DNA transposition" EXACT [GOC:dph] synonym: "stimulation of DNA transposition" NARROW [] synonym: "up regulation of DNA transposition" EXACT [] synonym: "up-regulation of DNA transposition" EXACT [] synonym: "upregulation of DNA transposition" EXACT [] xref: GO:0000336 is_a: CCO:P0000424 ! regulation of transposition, DNA-mediated is_a: CCO:P0000966 ! positive regulation of transposition [Term] id: CCO:P0000424 name: regulation of transposition, DNA-mediated namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule." [GOC:dph, GOC:krc] subset: gosubset_prok synonym: "regulation of DNA transposition" EXACT [GOC:dph] xref: GO:0000337 is_a: CCO:P0000964 ! regulation of transposition [Term] id: CCO:P0000425 name: regulation of alternative nuclear mRNA splicing, via spliceosome namespace: biological_process def: "Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs." [GOC:krc] synonym: "splice site selection" BROAD [] xref: GO:0000381 is_a: CCO:P0002767 ! regulation of nuclear mRNA splicing, via spliceosome [Term] id: CCO:P0000426 name: regulation of transcription by galactose namespace: biological_process def: "Any process involving galactose that modulates the frequency, rate or extent or transcription." [GOC:go_curators] subset: gosubset_prok xref: GO:0000409 is_a: CCO:P0002662 ! regulation of transcription by carbon catabolites [Term] id: CCO:P0000427 name: negative regulation of transcription by galactose namespace: biological_process def: "Any process involving galactose that stops, prevents or reduces the rate of transcription." [GOC:mah] synonym: "down regulation of transcription by galactose" EXACT [] synonym: "down-regulation of transcription by galactose" EXACT [] synonym: "downregulation of transcription by galactose" EXACT [] synonym: "inhibition of transcription by galactose" NARROW [] xref: GO:0000410 is_a: CCO:P0000426 ! regulation of transcription by galactose is_a: CCO:P0002260 ! negative regulation of transcription by carbon catabolites [Term] id: CCO:P0000428 name: positive regulation of transcription by galactose namespace: biological_process def: "Any process involving galactose that activates or increases the rate of transcription." [GOC:go_curators] synonym: "activation of transcription by galactose" NARROW [] synonym: "stimulation of transcription by galactose" NARROW [] synonym: "up regulation of transcription by galactose" EXACT [] synonym: "up-regulation of transcription by galactose" EXACT [] synonym: "upregulation of transcription by galactose" EXACT [] xref: GO:0000411 is_a: CCO:P0000426 ! regulation of transcription by galactose is_a: CCO:P0002663 ! positive regulation of transcription by carbon catabolites [Term] id: CCO:P0000429 name: regulation of histone H3-K36 methylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc] xref: GO:0000414 is_a: CCO:P0001370 ! regulation of histone methylation [Term] id: CCO:P0000430 name: negative regulation of histone H3-K36 methylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc] synonym: "down regulation of histone H3-K36 methylation" EXACT [] synonym: "down-regulation of histone H3-K36 methylation" EXACT [] synonym: "downregulation of histone H3-K36 methylation" EXACT [] synonym: "inhibition of histone H3-K36 methylation" NARROW [] xref: GO:0000415 is_a: CCO:P0000429 ! regulation of histone H3-K36 methylation is_a: CCO:P0001371 ! negative regulation of histone methylation [Term] id: CCO:P0000431 name: positive regulation of histone H3-K36 methylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3." [GOC:krc] synonym: "activation of histone H3-K36 methylation" NARROW [] synonym: "stimulation of histone H3-K36 methylation" NARROW [] synonym: "up regulation of histone H3-K36 methylation" EXACT [] synonym: "up-regulation of histone H3-K36 methylation" EXACT [] synonym: "upregulation of histone H3-K36 methylation" EXACT [] xref: GO:0000416 is_a: CCO:P0000429 ! regulation of histone H3-K36 methylation is_a: CCO:P0001372 ! positive regulation of histone methylation [Term] id: CCO:P0000432 name: regulation of transcription from RNA polymerase II promoter by carbon catabolites namespace: biological_process def: "Any process involving carbon catabolites that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] xref: GO:0000429 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter is_a: CCO:P0002662 ! regulation of transcription by carbon catabolites [Term] id: CCO:P0000433 name: regulation of transcription from RNA polymerase II promoter by glucose namespace: biological_process def: "Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] xref: GO:0000430 is_a: CCO:P0000432 ! regulation of transcription from RNA polymerase II promoter by carbon catabolites is_a: CCO:P0002677 ! regulation of transcription by glucose relationship: has_participant CCO:B0055146 ! USF1_HUMAN relationship: has_participant CCO:B0056117 ! USF2_HUMAN [Term] id: CCO:P0000434 name: regulation of transcription from RNA polymerase II promoter by galactose namespace: biological_process def: "Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] xref: GO:0000431 is_a: CCO:P0000426 ! regulation of transcription by galactose is_a: CCO:P0000432 ! regulation of transcription from RNA polymerase II promoter by carbon catabolites [Term] id: CCO:P0000435 name: positive regulation of transcription from RNA polymerase II promoter by glucose namespace: biological_process def: "Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:krc] synonym: "activation of transcription from RNA polymerase II promoter by glucose" NARROW [] synonym: "stimulation of transcription from RNA polymerase II promoter by glucose" NARROW [] synonym: "up regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] synonym: "up-regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] synonym: "upregulation of transcription from RNA polymerase II promoter by glucose" EXACT [] xref: GO:0000432 is_a: CCO:P0000433 ! regulation of transcription from RNA polymerase II promoter by glucose is_a: CCO:P0000439 ! positive regulation of transcription from RNA polymerase II promoter by carbon catabolites is_a: CCO:P0002678 ! positive regulation of transcription by glucose relationship: has_participant CCO:B0055146 ! USF1_HUMAN relationship: has_participant CCO:B0056117 ! USF2_HUMAN [Term] id: CCO:P0000436 name: negative regulation of transcription from RNA polymerase II promoter by glucose namespace: biological_process def: "Any process involving glucose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:krc] synonym: "down regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] synonym: "down-regulation of transcription from RNA polymerase II promoter by glucose" EXACT [] synonym: "downregulation of transcription from RNA polymerase II promoter by glucose" EXACT [] synonym: "inhibition of transcription from RNA polymerase II promoter by glucose" NARROW [] xref: GO:0000433 is_a: CCO:P0000433 ! regulation of transcription from RNA polymerase II promoter by glucose is_a: CCO:P0000440 ! negative regulation of transcription from RNA polymerase II promoter by carbon catabolites is_a: CCO:P0002261 ! negative regulation of transcription by glucose [Term] id: CCO:P0000437 name: negative regulation of transcription from RNA polymerase II promoter by galactose namespace: biological_process def: "Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:krc] synonym: "down regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] synonym: "down-regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] synonym: "downregulation of transcription from RNA polymerase II promoter by galactose" EXACT [] synonym: "inhibition of transcription from RNA polymerase II promoter by galactose" NARROW [] xref: GO:0000434 is_a: CCO:P0000427 ! negative regulation of transcription by galactose is_a: CCO:P0000434 ! regulation of transcription from RNA polymerase II promoter by galactose is_a: CCO:P0000440 ! negative regulation of transcription from RNA polymerase II promoter by carbon catabolites [Term] id: CCO:P0000438 name: positive regulation of transcription from RNA polymerase II promoter by galactose namespace: biological_process def: "Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:krc] synonym: "activation of transcription from RNA polymerase II promoter by galactose" NARROW [] synonym: "stimulation of transcription from RNA polymerase II promoter by galactose" NARROW [] synonym: "up regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] synonym: "up-regulation of transcription from RNA polymerase II promoter by galactose" EXACT [] synonym: "upregulation of transcription from RNA polymerase II promoter by galactose" EXACT [] xref: GO:0000435 is_a: CCO:P0000428 ! positive regulation of transcription by galactose is_a: CCO:P0000434 ! regulation of transcription from RNA polymerase II promoter by galactose is_a: CCO:P0000439 ! positive regulation of transcription from RNA polymerase II promoter by carbon catabolites [Term] id: CCO:P0000439 name: positive regulation of transcription from RNA polymerase II promoter by carbon catabolites namespace: biological_process def: "Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] synonym: "activation of transcription from RNA polymerase II promoter by carbon catabolites" NARROW [] synonym: "stimulation of transcription from RNA polymerase II promoter by carbon catabolites" NARROW [] synonym: "up regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [] synonym: "up-regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [] synonym: "upregulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [] xref: GO:0000436 is_a: CCO:P0000432 ! regulation of transcription from RNA polymerase II promoter by carbon catabolites is_a: CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter [Term] id: CCO:P0000440 name: negative regulation of transcription from RNA polymerase II promoter by carbon catabolites namespace: biological_process def: "Any process involving carbon catabolites that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:krc] synonym: "down regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [] synonym: "down-regulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [] synonym: "downregulation of transcription from RNA polymerase II promoter by carbon catabolites" EXACT [] synonym: "inhibition of transcription from RNA polymerase II promoter by carbon catabolites" NARROW [] xref: GO:0000437 is_a: CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter is_a: CCO:P0000432 ! regulation of transcription from RNA polymerase II promoter by carbon catabolites [Term] id: CCO:P0000441 name: gene conversion at mating-type locus, DNA double-strand break formation namespace: biological_process def: "The site-specific endonucleolytic cleavage of DNA at the mating-type locus which initiates the conversion of one mating-type allele to another." [GOC:elh, PMID:7646483] xref: GO:0000728 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000799 ! gene conversion at mating-type locus [Term] id: CCO:P0000442 name: DNA synthesis during DNA repair namespace: biological_process def: "Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template." [PMID:10357855] subset: gosubset_prok synonym: "DNA repair synthesis" BROAD [] xref: GO:0000731 xref: Reactome:76011 is_a: CCO:P0000628 ! DNA replication relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN relationship: has_participant CCO:B0014914 ! POLH_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0058386 ! WRIP1_HUMAN [Term] id: CCO:P0000443 name: gene conversion at mating-type locus, DNA repair synthesis namespace: biological_process def: "Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template during gene conversion at the mating-type locus." [GOC:elh] xref: GO:0000734 is_a: CCO:P0000442 ! DNA synthesis during DNA repair relationship: part_of CCO:P0000799 ! gene conversion at mating-type locus [Term] id: CCO:P0000444 name: removal of nonhomologous ends namespace: biological_process def: "The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur." [PMID:10357855] xref: GO:0000735 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000799 ! gene conversion at mating-type locus [Term] id: CCO:P0000445 name: pheromone-dependent signal transduction during conjugation with cellular fusion namespace: biological_process def: "A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion." [GOC:clt] synonym: "MAPKKK cascade (mating sensu Fungi)" RELATED [] synonym: "MAPKKK cascade (mating sensu Saccharomyces)" RELATED [] synonym: "signal transduction of mating signal (sensu Saccharomyces)" NARROW [] synonym: "transduction of mating signal (sensu Fungi)" NARROW [] xref: GO:0000750 xref: GO:0007330 xref: GO:0030454 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway is_a: CCO:P0001521 ! signal transduction during conjugation with cellular fusion [Term] id: CCO:P0000446 name: adaptation to pheromone during conjugation with cellular fusion namespace: biological_process def: "In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses." [GOC:clt] synonym: "adaptation to mating signal (sensu Fungi)" NARROW [] synonym: "adaptation to mating signal (sensu Saccharomyces)" NARROW [] synonym: "desensitization to pheromone during conjugation with cellular fusion" EXACT [] xref: GO:0000754 xref: GO:0007331 xref: GO:0030453 is_a: CCO:P0001236 ! adaptation of signaling pathway [Term] id: CCO:P0000447 name: cytogamy namespace: biological_process def: "During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing." [GOC:elh] synonym: "zygote formation (sensu Fungi)" NARROW [] xref: GO:0000218 xref: GO:0000755 xref: GO:0030462 is_a: CCO:P0001240 ! reproductive process in single-celled organism [Term] id: CCO:P0000448 name: signal transduction during conjugation without cellular fusion namespace: biological_process def: "A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion." [GOC:clt] xref: GO:0000757 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0000449 name: adaptation to pheromone during conjugation without cellular fusion namespace: biological_process def: "In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses." [GOC:clt] synonym: "desensitization to pheromone during conjugation without cellular fusion" EXACT [] xref: GO:0000760 is_a: CCO:P0001236 ! adaptation of signaling pathway [Term] id: CCO:P0000450 name: adaptation to pheromone during pheromone-induced unidirectional conjugation namespace: biological_process def: "In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses." [GOC:clt] synonym: "desensitization to pheromone during pheromone-induced unidirectional conjugation" EXACT [] xref: GO:0000766 is_a: CCO:P0001236 ! adaptation of signaling pathway [Term] id: CCO:P0000451 name: regulation of glutamine family amino acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline." [GOC:goc_curators] synonym: "regulation of glutamine family amino acid metabolism" EXACT [] xref: GO:0000820 is_a: CCO:P0000668 ! regulation of amino acid metabolic process [Term] id: CCO:P0000452 name: regulation of arginine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid." [ChEBI:29016, GOC:go_curators] synonym: "regulation of arginine metabolism" EXACT [] xref: GO:0000821 is_a: CCO:P0000451 ! regulation of glutamine family amino acid metabolic process [Term] id: CCO:P0000453 name: cytokinesis namespace: biological_process def: "A cellular process resulting in the division of the cytoplasm of a cell and its separation into two daughter cells. Cytokinesis usually occurs after growth, replication, and segregation of cellular components." [GOC:ai] subset: goslim_candida subset: goslim_yeast subset: gosubset_prok xref: GO:0000910 xref: GO:0007104 xref: GO:0016288 xref: Reactome:211912 xref: Reactome:221676 xref: Reactome:230265 xref: Reactome:238302 xref: Reactome:244868 xref: Reactome:249758 xref: Reactome:252506 xref: Reactome:259076 xref: Reactome:262434 xref: Reactome:265269 xref: Reactome:268395 xref: Reactome:282835 xref: Reactome:286599 xref: Reactome:68884 is_a: CCO:P0003077 ! cell division relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001382 ! SEPT4_HUMAN relationship: has_participant CCO:B0001394 ! PRC1_HUMAN relationship: has_participant CCO:B0001440 ! DCTN3_HUMAN relationship: has_participant CCO:B0001775 ! SEPT6_HUMAN relationship: has_participant CCO:B0001787 ! ESPL1_HUMAN relationship: has_participant CCO:B0001816 ! SEPT7_HUMAN relationship: has_participant CCO:B0001961 ! CNTRB_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0002155 ! ANLN_HUMAN relationship: has_participant CCO:B0002156 ! BIN3_HUMAN relationship: has_participant CCO:B0002198 ! SEPT3_HUMAN relationship: has_participant CCO:B0002242 ! AURKC_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0033316 ! DEST_HUMAN relationship: has_participant CCO:B0054197 ! B0YJ91_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN relationship: has_participant CCO:B0054584 ! DIAP2_HUMAN relationship: has_participant CCO:B0054602 ! ROCK2_HUMAN relationship: has_participant CCO:B0055261 ! STX2_HUMAN relationship: has_participant CCO:B0055910 ! ROCK1_HUMAN relationship: has_participant CCO:B0056034 ! Q14DU5_HUMAN relationship: has_participant CCO:B0056054 ! RAB35_HUMAN relationship: has_participant CCO:B0058335 ! NOX5_HUMAN relationship: has_participant CCO:B0058552 ! CECR2_HUMAN relationship: has_participant CCO:B0058611 ! ROP1B_HUMAN [Term] id: CCO:P0000454 name: barrier septum formation namespace: biological_process def: "The process of making a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a barrier septum are not able to exchange intracellular material." [GOC:clt] synonym: "formation of barrier septum" EXACT [] synonym: "septation" BROAD [] synonym: "septin assembly and septum biosynthesis" RELATED [] synonym: "septin assembly and septum formation" RELATED [] xref: GO:0000917 is_a: CCO:P0001637 ! cytokinetic process relationship: has_participant CCO:B0002156 ! BIN3_HUMAN [Term] id: CCO:P0000455 name: selection of site for barrier septum formation namespace: biological_process def: "The process of marking the site where a barrier septum will form." [GOC:clt] synonym: "selection of site for barrier cell septum biosynthesis" EXACT [] synonym: "selection of site for barrier cell septum formation" EXACT [] synonym: "septin assembly and septum biosynthesis" BROAD [] synonym: "septin assembly and septum formation" BROAD [] synonym: "septum positioning" EXACT [] xref: GO:0000918 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000454 ! barrier septum formation [Term] id: CCO:P0000456 name: cell separation during cytokinesis namespace: biological_process def: "The process of physically separating progeny cells during cytokinesis; this may involve enzymatic digestion of septum or cell wall components." [GOC:clt] synonym: "rotokinesis" NARROW [] xref: GO:0000920 is_a: CCO:P0001637 ! cytokinetic process relationship: has_participant CCO:B0055261 ! STX2_HUMAN [Term] id: CCO:P0000457 name: regulation of mitochondrial RNA catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." [GOC:krc, GOC:mah] xref: GO:0000960 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0003068 ! regulation of RNA metabolic process [Term] id: CCO:P0000458 name: negative regulation of mitochondrial RNA catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." [GOC:krc, GOC:mah] xref: GO:0000961 is_a: CCO:P0000457 ! regulation of mitochondrial RNA catabolic process is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0003069 ! negative regulation of RNA metabolic process [Term] id: CCO:P0000459 name: positive regulation of mitochondrial RNA catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." [GOC:krc, GOC:mah] xref: GO:0000962 is_a: CCO:P0000457 ! regulation of mitochondrial RNA catabolic process is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0003070 ! positive regulation of RNA metabolic process [Term] id: CCO:P0000460 name: loss of chromatin silencing during replicative cell aging namespace: biological_process def: "The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins." [GOC:jh, PMID:12044934] synonym: "loss of chromatin silencing during replicative cell ageing" EXACT [] xref: GO:0001308 is_a: CCO:P0000651 ! loss of chromatin silencing [Term] id: CCO:P0000461 name: replication of extrachromosomal rDNA circles during replicative cell aging namespace: biological_process def: "Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication." [GOC:jh, PMID:12044934] synonym: "replication of extrachromosomal rDNA circles during replicative cell ageing" EXACT [] synonym: "replication of extrachromosomal ribosomal DNA circles during replicative cell aging" EXACT [] xref: GO:0001312 is_a: CCO:P0000462 ! replication of extrachromosomal circular DNA during replicative cell aging [Term] id: CCO:P0000462 name: replication of extrachromosomal circular DNA during replicative cell aging namespace: biological_process def: "Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication." [GOC:jh] synonym: "replication of extrachromosomal circular DNA during replicative cell ageing" EXACT [] xref: GO:0001314 is_a: CCO:P0000463 ! replication of extrachromosomal circular DNA [Term] id: CCO:P0000463 name: replication of extrachromosomal circular DNA namespace: biological_process def: "Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication." [GOC:jh] subset: gosubset_prok xref: GO:0001326 is_a: CCO:P0000628 ! DNA replication [Term] id: CCO:P0000464 name: signal transduction during filamentous growth namespace: biological_process def: "Relaying of environmental signals promoting filamentous growth." [GOC:mcc, PMID:9728395] synonym: "MAPKKK cascade (pseudohyphal growth)" RELATED [] xref: GO:0001402 is_a: CCO:P0000708 ! signal transduction [Term] id: CCO:P0000465 name: selenocysteine incorporation namespace: biological_process def: "The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine." [RESID:AA0022] subset: gosubset_prok xref: GO:0001514 xref: RESID:AA0022 is_a: CCO:P0000666 ! translational readthrough relationship: has_participant CCO:B0026033 ! SPCS_HUMAN relationship: has_participant CCO:B0029172 ! TSAP1_HUMAN relationship: has_participant CCO:B0055561 ! SELB_HUMAN relationship: has_participant CCO:B0055617 ! SELT_HUMAN relationship: has_participant CCO:B0057334 ! PSTK_HUMAN relationship: has_participant CCO:B0058097 ! IOD2_HUMAN [Term] id: CCO:P0000466 name: regulation of cell growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell growth." [GOC:go_curators] subset: gosubset_prok xref: GO:0001558 xref: Reactome:110498 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001634 ! VEGFB_HUMAN relationship: has_participant CCO:B0001782 ! CASL_HUMAN relationship: has_participant CCO:B0001796 ! HECAM_HUMAN relationship: has_participant CCO:B0001904 ! KCD11_HUMAN relationship: has_participant CCO:B0002075 ! NECD_HUMAN relationship: has_participant CCO:B0002241 ! CD2L2_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0005283 ! TS101_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005917 ! MO4L1_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN relationship: has_participant CCO:B0016505 ! KCC2D_HUMAN relationship: has_participant CCO:B0017118 ! ING2_HUMAN relationship: has_participant CCO:B0019513 ! TAOK2_HUMAN relationship: has_participant CCO:B0021692 ! WISP1_HUMAN relationship: has_participant CCO:B0021695 ! Q6PEG3_HUMAN relationship: has_participant CCO:B0021696 ! CTGF_HUMAN relationship: has_participant CCO:B0021697 ! NOV_HUMAN relationship: has_participant CCO:B0021699 ! WISP2_HUMAN relationship: has_participant CCO:B0021887 ! I17RB_HUMAN relationship: has_participant CCO:B0022431 ! OSGI1_HUMAN relationship: has_participant CCO:B0022490 ! MAGG1_HUMAN relationship: has_participant CCO:B0023930 ! BRM1L_HUMAN relationship: has_participant CCO:B0024022 ! PAK2_HUMAN relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0028029 ! GO45_HUMAN relationship: has_participant CCO:B0029357 ! EGLN2_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0034258 ! GAS6_HUMAN relationship: has_participant CCO:B0041249 ! HMGA2_HUMAN relationship: has_participant CCO:B0041257 ! E4F1_HUMAN relationship: has_participant CCO:B0043535 ! UB2E3_HUMAN relationship: has_participant CCO:B0043817 ! NGX6_HUMAN relationship: has_participant CCO:B0054331 ! RCAS1_HUMAN relationship: has_participant CCO:B0054337 ! CYR61_HUMAN relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0054347 ! SOCS7_HUMAN relationship: has_participant CCO:B0054349 ! SOCS6_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN relationship: has_participant CCO:B0054430 ! CHAD_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN relationship: has_participant CCO:B0054660 ! CREG1_HUMAN relationship: has_participant CCO:B0054734 ! CSPG5_HUMAN relationship: has_participant CCO:B0054755 ! WISP3_HUMAN relationship: has_participant CCO:B0054808 ! O95958_HUMAN relationship: has_participant CCO:B0054816 ! F107A_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0054932 ! IBP1_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055091 ! NEUM_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN relationship: has_participant CCO:B0055098 ! IBP2_HUMAN relationship: has_participant CCO:B0055149 ! IBP4_HUMAN relationship: has_participant CCO:B0055173 ! IBP6_HUMAN relationship: has_participant CCO:B0055174 ! IBP5_HUMAN relationship: has_participant CCO:B0055223 ! AGTR1_HUMAN relationship: has_participant CCO:B0055554 ! NRG3_HUMAN relationship: has_participant CCO:B0055659 ! HTRA3_HUMAN relationship: has_participant CCO:B0056127 ! ENOX2_HUMAN relationship: has_participant CCO:B0056131 ! IBP7_HUMAN relationship: has_participant CCO:B0056257 ! Q3KR29_HUMAN relationship: has_participant CCO:B0056258 ! Q3KR30_HUMAN relationship: has_participant CCO:B0056277 ! Q3V4E3_HUMAN relationship: has_participant CCO:B0056391 ! Q59FF1_HUMAN relationship: has_participant CCO:B0056418 ! TMM97_HUMAN relationship: has_participant CCO:B0056422 ! IGS11_HUMAN relationship: has_participant CCO:B0056450 ! Q5JBS6_HUMAN relationship: has_participant CCO:B0056819 ! CAPR2_HUMAN relationship: has_participant CCO:B0057053 ! Q6ZSD0_HUMAN relationship: has_participant CCO:B0057123 ! GRP2_HUMAN relationship: has_participant CCO:B0057190 ! ARHG8_HUMAN relationship: has_participant CCO:B0057443 ! ARM10_HUMAN relationship: has_participant CCO:B0057449 ! LTBP4_HUMAN relationship: has_participant CCO:B0057462 ! FGRL1_HUMAN relationship: has_participant CCO:B0057532 ! ABTB2_HUMAN relationship: has_participant CCO:B0057978 ! CHPT1_HUMAN relationship: has_participant CCO:B0058010 ! IBPL1_HUMAN relationship: has_participant CCO:B0058020 ! SOCS4_HUMAN relationship: has_participant CCO:B0058044 ! Q8WYK7_HUMAN relationship: has_participant CCO:B0058087 ! HTRA1_HUMAN relationship: has_participant CCO:B0058226 ! KAZD1_HUMAN relationship: has_participant CCO:B0058235 ! ITCH_HUMAN relationship: has_participant CCO:B0058562 ! PAPP2_HUMAN relationship: has_participant CCO:B0058651 ! BRD8_HUMAN relationship: has_participant CCO:B0058759 ! ZMAT3_HUMAN relationship: has_participant CCO:B0058849 ! CD320_HUMAN relationship: has_participant CCO:B0058859 ! ESM1_HUMAN relationship: has_participant CCO:B0058919 ! CISH_HUMAN relationship: has_participant CCO:B0059017 ! OGFR_HUMAN relationship: has_participant CCO:B0059020 ! CRIM1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059157 ! Q9UID7_HUMAN relationship: has_participant CCO:B0059196 ! MUC12_HUMAN [Term] id: CCO:P0000467 name: regulation of cell growth by detection of nuclear:cytoplasmic ratio namespace: biological_process def: "Any process whereby the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time." [GOC:dph] synonym: "detection of nuclear:cytoplasmic ratio to regulate cell growth" EXACT [] synonym: "interpretation of nuclear:cytoplasmic ratio to regulate cell growth" EXACT [] synonym: "regulation of cell growth by nuclear:cytoplasmic ratio" EXACT [] synonym: "regulation of cell growth by sensing of nuclear:cytoplasmic ratio" EXACT [] xref: GO:0001559 is_a: CCO:P0000466 ! regulation of cell growth [Term] id: CCO:P0000468 name: regulation of cell growth by extracellular stimulus namespace: biological_process def: "Any process whereby external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time." [GOC:dph] synonym: "interpretation of external signals that regulate cell growth" EXACT [] synonym: "regulation of cell growth by detection of exogenous stimulus" EXACT [] synonym: "regulation of cell growth by sensing of exogenous stimulus" EXACT [] synonym: "regulation of growth by exogenous signal" EXACT [] synonym: "regulation of growth by exogenous stimuli" EXACT [] synonym: "regulation of growth by exogenous stimulus" EXACT [] synonym: "regulation of growth by external signal" EXACT [] synonym: "regulation of growth by external stimuli" EXACT [] synonym: "regulation of growth by external stimulus" EXACT [] xref: GO:0001560 is_a: CCO:P0000466 ! regulation of cell growth is_a: CCO:P0000708 ! signal transduction relationship: has_participant CCO:B0002060 ! NEB2_HUMAN [Term] id: CCO:P0000469 name: regulation of chromatin assembly or disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly." [GOC:go_curators] synonym: "regulation of chromatin assembly/disassembly" EXACT [] xref: GO:0001672 is_a: CCO:P0001766 ! regulation of chromosome organization and biogenesis relationship: has_participant CCO:B0001939 ! TLK2_HUMAN relationship: has_participant CCO:B0002220 ! TLK1_HUMAN [Term] id: CCO:P0000470 name: T cell homeostatic proliferation namespace: biological_process def: "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." [GOC:mgi_curators, ISBN:0781735149 "Fundamental Immunology"] synonym: "resting T cell proliferation" EXACT [] synonym: "resting T-cell proliferation" EXACT [] synonym: "T lymphocyte homeostatic proliferation" EXACT [] synonym: "T-cell homeostatic proliferation" EXACT [] synonym: "T-lymphocyte homeostatic proliferation" EXACT [] xref: GO:0001777 is_a: CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0000471 name: natural killer cell proliferation namespace: biological_process def: "The expansion of a natural killer cell population by cell division." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "NK cell proliferation" EXACT [] xref: GO:0001787 is_a: CCO:P0002724 ! lymphocyte proliferation relationship: has_participant CCO:B0058430 ! ELF4_HUMAN [Term] id: CCO:P0000472 name: antibody-dependent cellular cytotoxicity namespace: biological_process def: "Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells." [ISBN:0781735149 "Fundamental Immunology", PMID:11677095, PMID:9581795] synonym: "ADCC" EXACT [] synonym: "antibody dependent cell death" EXACT [] synonym: "antibody dependent cell killing" EXACT [] synonym: "antibody-dependent cell death" EXACT [] synonym: "antibody-dependent cell killing" EXACT [] synonym: "type VI hypersensitivity" EXACT [] xref: GO:0001788 is_a: CCO:P0000672 ! induction of apoptosis [Term] id: CCO:P0000473 name: G-protein signaling, coupled to S1P second messenger (sphingosine kinase activating) namespace: biological_process def: "A G-protein coupled signaling pathway that results in the activation of sphingosine kinase, causing an increase in cellular levels of sphingosine-1-phosphate." [GOC:dph, PMID:14592418] synonym: "G protein signaling, coupled to S1P second messenger (sphingosine kinase activating)" EXACT [] synonym: "G protein signalling, coupled to S1P second messenger (sphingosine kinase activating)" EXACT [] synonym: "G-protein signalling, coupled to S1P second messenger (sphingosine kinase activating)" EXACT [] xref: GO:0001789 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0000474 name: regulation of antibody-dependent cellular cytotoxicity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of antibody dependent cell death" EXACT [] synonym: "regulation of antibody dependent cell killing" EXACT [] synonym: "regulation of antibody-dependent cell death" EXACT [] synonym: "regulation of antibody-dependent cell killing" EXACT [] xref: GO:0001813 is_a: CCO:U0000002 ! biological process relationship: regulates CCO:P0000472 ! antibody-dependent cellular cytotoxicity [Term] id: CCO:P0000475 name: negative regulation of antibody-dependent cellular cytotoxicity namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of antibody-dependent cellular cytotoxicity" EXACT [] synonym: "down-regulation of antibody-dependent cellular cytotoxicity" EXACT [] synonym: "downregulation of antibody-dependent cellular cytotoxicity" EXACT [] synonym: "inhibition of antibody-dependent cellular cytotoxicity" NARROW [] synonym: "negative regulation of antibody dependent cell death" EXACT [] synonym: "negative regulation of antibody dependent cell killing" EXACT [] synonym: "negative regulation of antibody-dependent cell death" EXACT [] synonym: "negative regulation of antibody-dependent cell killing" EXACT [] xref: GO:0001814 is_a: CCO:P0000474 ! regulation of antibody-dependent cellular cytotoxicity relationship: negatively_regulates CCO:P0000472 ! antibody-dependent cellular cytotoxicity [Term] id: CCO:P0000476 name: positive regulation of antibody-dependent cellular cytotoxicity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of antibody-dependent cellular cytotoxicity" NARROW [] synonym: "positive regulation of antibody dependent cell death" EXACT [] synonym: "positive regulation of antibody dependent cell killing" EXACT [] synonym: "positive regulation of antibody-dependent cell death" EXACT [] synonym: "positive regulation of antibody-dependent cell killing" EXACT [] synonym: "stimulation of antibody-dependent cellular cytotoxicity" NARROW [] synonym: "up regulation of antibody-dependent cellular cytotoxicity" EXACT [] synonym: "up-regulation of antibody-dependent cellular cytotoxicity" EXACT [] synonym: "upregulation of antibody-dependent cellular cytotoxicity" EXACT [] xref: GO:0001815 is_a: CCO:P0000474 ! regulation of antibody-dependent cellular cytotoxicity relationship: positively_regulates CCO:P0000472 ! antibody-dependent cellular cytotoxicity [Term] id: CCO:P0000477 name: inner cell mass cell proliferation namespace: biological_process def: "The proliferation of cells in the inner cell mass." [GOC:dph, GOC:isa_complete, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'. xref: GO:0001833 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0016149 ! PRP19_HUMAN relationship: has_participant CCO:B0025212 ! SBDS_HUMAN relationship: has_participant CCO:B0056011 ! PSF1_HUMAN [Term] id: CCO:P0000478 name: trophectodermal cell proliferation namespace: biological_process def: "The proliferation of cells in the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. synonym: "trophectoderm cell proliferation" EXACT [] xref: GO:0001834 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0000479 name: release of cytochrome c from mitochondria namespace: biological_process def: "The process by which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation." [GOC:add, GOC:mah, ISBN:0721639976, PMID:12925707, PMID:9560217] xref: GO:0001836 is_a: CCO:P0000844 ! apoptotic mitochondrial changes relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN relationship: has_participant CCO:B0006340 ! APR_HUMAN relationship: has_participant CCO:B0033778 ! SODM_HUMAN relationship: has_participant CCO:B0054910 ! GPX1_HUMAN relationship: has_participant CCO:B0054951 ! IFI6_HUMAN [Term] id: CCO:P0000480 name: epithelial to mesenchymal transition namespace: biological_process def: "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, PMID:14701881] synonym: "EMT" EXACT [] synonym: "epithelial-mesenchymal transition" EXACT [] xref: GO:0001837 is_a: CCO:P0003288 ! delamination relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0001518 ! HGF_HUMAN relationship: has_participant CCO:B0001531 ! BMP7_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0019310 ! S10A4_HUMAN relationship: has_participant CCO:B0055403 ! SOX9_HUMAN relationship: has_participant CCO:B0058447 ! ROAA_HUMAN [Term] id: CCO:P0000481 name: protein insertion into mitochondrial membrane during induction of apoptosis namespace: biological_process def: "The process by which a protein is incorporated into a mitochondrial membrane as an early step in apoptosis." [GOC:add, PMID:12952892] comment: Note that this term is intended to cover the insertion of pro-apoptotic proteins such as Bax or its homologs into mitochondrial membranes which occurs as an early step in the apoptotic program. synonym: "insertion of proteins into mitochondrial membranes during the induction of apoptosis" EXACT [] synonym: "protein insertion into mitochondrion membrane during induction of apoptosis" EXACT [] xref: GO:0001844 xref: Reactome:114264 xref: Reactome:139905 xref: Reactome:139909 xref: Reactome:139914 xref: Reactome:139919 xref: Reactome:140216 xref: Reactome:211289 xref: Reactome:211290 xref: Reactome:211292 xref: Reactome:211294 xref: Reactome:211310 xref: Reactome:211313 xref: Reactome:221100 xref: Reactome:221101 xref: Reactome:221103 xref: Reactome:221105 xref: Reactome:221120 xref: Reactome:229760 xref: Reactome:229762 xref: Reactome:237763 xref: Reactome:237765 is_a: CCO:P0000844 ! apoptotic mitochondrial changes relationship: has_participant CCO:B0059333 ! SHLB1_HUMAN relationship: part_of CCO:P0000672 ! induction of apoptosis [Term] id: CCO:P0000482 name: NK T cell proliferation namespace: biological_process def: "The expansion of a NK T cell population by cell division." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:10704459] comment: Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. synonym: "natural killer T cell proliferation" EXACT [] synonym: "natural T cell proliferation" EXACT [] synonym: "NK T lymphocyte proliferation" EXACT [] synonym: "NK T-cell proliferation" EXACT [] synonym: "NK T-lymphocyte proliferation" EXACT [] synonym: "NKT cell proliferation" EXACT [] synonym: "NT cell proliferation" EXACT [] xref: GO:0001866 is_a: CCO:P0002708 ! alpha-beta T cell proliferation relationship: has_participant CCO:B0058430 ! ELF4_HUMAN [Term] id: CCO:P0000483 name: regulation of complement activation, lectin pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001868 is_a: CCO:P0001263 ! regulation of complement activation [Term] id: CCO:P0000484 name: negative regulation of complement activation, lectin pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of complement activation, lectin pathway" EXACT [] synonym: "down-regulation of complement activation, lectin pathway" EXACT [] synonym: "downregulation of complement activation, lectin pathway" EXACT [] synonym: "inhibition of complement activation, lectin pathway" NARROW [] xref: GO:0001869 is_a: CCO:P0000483 ! regulation of complement activation, lectin pathway is_a: CCO:P0002611 ! negative regulation of complement activation [Term] id: CCO:P0000485 name: positive regulation of complement activation, lectin pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of complement activation, lectin pathway" NARROW [] synonym: "stimulation of complement activation, lectin pathway" NARROW [] synonym: "up regulation of complement activation, lectin pathway" EXACT [] synonym: "up-regulation of complement activation, lectin pathway" EXACT [] synonym: "upregulation of complement activation, lectin pathway" EXACT [] xref: GO:0001870 is_a: CCO:P0000483 ! regulation of complement activation, lectin pathway is_a: CCO:P0002612 ! positive regulation of complement activation [Term] id: CCO:P0000486 name: receptor recycling namespace: biological_process def: "The process by which receptor molecules are returned to an active state and in an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal." [GOC:dph] xref: GO:0001881 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0055415 ! CAMLG_HUMAN relationship: has_participant CCO:B0058350 ! ALS2_HUMAN relationship: part_of CCO:P0000708 ! signal transduction [Term] id: CCO:P0000487 name: T cell mediated cytotoxicity namespace: biological_process def: "The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:11911826] comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, independently of their definition as 'helper' T cells or not. synonym: "T cell mediated apoptosis" EXACT [] synonym: "T cell mediated cell death" EXACT [] synonym: "T cell mediated cell killing" EXACT [] synonym: "T cell mediated cytolysis" RELATED [] synonym: "T lymphocyte mediated cytotoxicity" EXACT [] synonym: "T-cell mediated apoptosis" EXACT [] synonym: "T-cell mediated cell death" EXACT [] synonym: "T-cell mediated cell killing" EXACT [] synonym: "T-cell mediated cytotoxicity" EXACT [] synonym: "T-lymphocyte mediated cytotoxicity" EXACT [] xref: GO:0001913 is_a: CCO:P0000672 ! induction of apoptosis [Term] id: CCO:P0000488 name: regulation of T cell mediated cytotoxicity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of T cell mediated apoptosis" EXACT [] synonym: "regulation of T cell mediated cell death" EXACT [] synonym: "regulation of T cell mediated cell killing" EXACT [] synonym: "regulation of T cell mediated cytolysis" RELATED [] synonym: "regulation of T lymphocyte mediated cytotoxicity" EXACT [] synonym: "regulation of T-cell mediated apoptosis" EXACT [] synonym: "regulation of T-cell mediated cell death" EXACT [] synonym: "regulation of T-cell mediated cell killing" EXACT [] synonym: "regulation of T-cell mediated cytolysis" RELATED [] synonym: "regulation of T-cell mediated cytotoxicity" EXACT [] synonym: "regulation of T-lymphocyte mediated cytotoxicity" EXACT [] xref: GO:0001914 is_a: CCO:U0000002 ! biological process relationship: regulates CCO:P0000487 ! T cell mediated cytotoxicity [Term] id: CCO:P0000489 name: negative regulation of T cell mediated cytotoxicity namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of T cell mediated cytotoxicity" EXACT [] synonym: "down-regulation of T cell mediated cytotoxicity" EXACT [] synonym: "downregulation of T cell mediated cytotoxicity" EXACT [] synonym: "inhibition of T cell mediated cytotoxicity" NARROW [] synonym: "negative regulation of T cell mediated apoptosis" EXACT [] synonym: "negative regulation of T cell mediated cell death" EXACT [] synonym: "negative regulation of T cell mediated cell killing" EXACT [] synonym: "negative regulation of T cell mediated cytolysis" RELATED [] synonym: "negative regulation of T lymphocyte mediated cytotoxicity" EXACT [] synonym: "negative regulation of T-cell mediated apoptosis" EXACT [] synonym: "negative regulation of T-cell mediated cell death" EXACT [] synonym: "negative regulation of T-cell mediated cell killing" EXACT [] synonym: "negative regulation of T-cell mediated cytolysis" RELATED [] synonym: "negative regulation of T-cell mediated cytotoxicity" EXACT [] synonym: "negative regulation of T-lymphocyte mediated cytotoxicity" EXACT [] xref: GO:0001915 is_a: CCO:P0000488 ! regulation of T cell mediated cytotoxicity relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: negatively_regulates CCO:P0000487 ! T cell mediated cytotoxicity [Term] id: CCO:P0000490 name: positive regulation of T cell mediated cytotoxicity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of T cell mediated cytotoxicity" NARROW [] synonym: "positive regulation of T cell mediated apoptosis" EXACT [] synonym: "positive regulation of T cell mediated cell death" EXACT [] synonym: "positive regulation of T cell mediated cell killing" EXACT [] synonym: "positive regulation of T cell mediated cytolysis" RELATED [] synonym: "positive regulation of T lymphocyte mediated cytotoxicity" EXACT [] synonym: "positive regulation of T-cell mediated apoptosis" EXACT [] synonym: "positive regulation of T-cell mediated cell death" EXACT [] synonym: "positive regulation of T-cell mediated cell killing" EXACT [] synonym: "positive regulation of T-cell mediated cytolysis" RELATED [] synonym: "positive regulation of T-cell mediated cytotoxicity" EXACT [] synonym: "positive regulation of T-lymphocyte mediated cytotoxicity" EXACT [] synonym: "stimulation of T cell mediated cytotoxicity" NARROW [] synonym: "up regulation of T cell mediated cytotoxicity" EXACT [] synonym: "up-regulation of T cell mediated cytotoxicity" EXACT [] synonym: "upregulation of T cell mediated cytotoxicity" EXACT [] xref: GO:0001916 is_a: CCO:P0000488 ! regulation of T cell mediated cytotoxicity relationship: positively_regulates CCO:P0000487 ! T cell mediated cytotoxicity [Term] id: CCO:P0000491 name: regulation of receptor recycling namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of receptor recyling." [GOC:add] xref: GO:0001919 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process relationship: has_participant CCO:B0059023 ! CHMP5_HUMAN relationship: regulates CCO:P0000486 ! receptor recycling [Term] id: CCO:P0000492 name: negative regulation of receptor recycling namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of receptor recyling." [GOC:add] synonym: "down regulation of receptor recycling" EXACT [] synonym: "down-regulation of receptor recycling" EXACT [] synonym: "downregulation of receptor recycling" EXACT [] synonym: "inhibition of receptor recycling" NARROW [] xref: GO:0001920 is_a: CCO:P0000491 ! regulation of receptor recycling is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process relationship: has_participant CCO:B0056916 ! TRAT1_HUMAN relationship: negatively_regulates CCO:P0000486 ! receptor recycling [Term] id: CCO:P0000493 name: positive regulation of receptor recycling namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of receptor recyling." [GOC:add] synonym: "activation of receptor recycling" NARROW [] synonym: "stimulation of receptor recycling" NARROW [] synonym: "up regulation of receptor recycling" EXACT [] synonym: "up-regulation of receptor recycling" EXACT [] synonym: "upregulation of receptor recycling" EXACT [] xref: GO:0001921 is_a: CCO:P0000491 ! regulation of receptor recycling is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process relationship: positively_regulates CCO:P0000486 ! receptor recycling [Term] id: CCO:P0000494 name: regulation of B-1 B cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of B-1 B lymphocyte differentiation" EXACT [] synonym: "regulation of B-1 B-cell differentiation" EXACT [] synonym: "regulation of B-1 B-lymphocyte differentiation" EXACT [] xref: GO:0001924 is_a: CCO:P0002391 ! regulation of B cell differentiation [Term] id: CCO:P0000495 name: negative regulation of B-1 B cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of B-1 B cell differentiation" EXACT [] synonym: "down-regulation of B-1 B cell differentiation" EXACT [] synonym: "downregulation of B-1 B cell differentiation" EXACT [] synonym: "inhibition of B-1 B cell differentiation" NARROW [] synonym: "negative regulation of B-1 B lymphocyte differentiation" EXACT [] synonym: "negative regulation of B-1 B-cell differentiation" EXACT [] synonym: "negative regulation of B-1 B-lymphocyte differentiation" EXACT [] xref: GO:0001925 is_a: CCO:P0000494 ! regulation of B-1 B cell differentiation is_a: CCO:P0002392 ! negative regulation of B cell differentiation [Term] id: CCO:P0000496 name: positive regulation of B-1 B cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of B-1 B cell differentiation" NARROW [] synonym: "positive regulation of B-1 B lymphocyte differentiation" EXACT [] synonym: "positive regulation of B-1 B-cell differentiation" EXACT [] synonym: "positive regulation of B-1 B-lymphocyte differentiation" EXACT [] synonym: "stimulation of B-1 B cell differentiation" NARROW [] synonym: "up regulation of B-1 B cell differentiation" EXACT [] synonym: "up-regulation of B-1 B cell differentiation" EXACT [] synonym: "upregulation of B-1 B cell differentiation" EXACT [] xref: GO:0001926 is_a: CCO:P0000494 ! regulation of B-1 B cell differentiation is_a: CCO:P0002393 ! positive regulation of B cell differentiation [Term] id: CCO:P0000497 name: regulation of exocyst assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of exocyst assembly." [GOC:hjd] comment: Note that the assembly is regulated by several small GTPases of the Rab and Rho families. xref: GO:0001928 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process is_a: CCO:P0002176 ! regulation of protein complex assembly [Term] id: CCO:P0000498 name: negative regulation of exocyst assembly namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of exocyst assembly." [GOC:hjd] synonym: "down regulation of exocyst assembly" EXACT [] synonym: "down-regulation of exocyst assembly" EXACT [] synonym: "downregulation of exocyst assembly" EXACT [] synonym: "inhibition of exocyst assembly" NARROW [] xref: GO:0001929 is_a: CCO:P0000497 ! regulation of exocyst assembly is_a: CCO:P0001413 ! negative regulation of protein complex assembly is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process [Term] id: CCO:P0000499 name: positive regulation of exocyst assembly namespace: biological_process def: "Any process that increases the rate or extent of exocyst assembly." [GOC:hjd] synonym: "activation of exocyst assembly" NARROW [] synonym: "stimulation of exocyst assembly" NARROW [] synonym: "up regulation of exocyst assembly" EXACT [] synonym: "up-regulation of exocyst assembly" EXACT [] synonym: "upregulation of exocyst assembly" EXACT [] xref: GO:0001930 is_a: CCO:P0000497 ! regulation of exocyst assembly is_a: CCO:P0001414 ! positive regulation of protein complex assembly is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process [Term] id: CCO:P0000500 name: regulation of protein amino acid phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." [GOC:hjd] subset: gosubset_prok xref: GO:0001932 is_a: CCO:P0001433 ! regulation of protein modification process is_a: CCO:P0002057 ! regulation of phosphorylation relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN relationship: has_participant CCO:B0014816 ! KGP1A_HUMAN relationship: has_participant CCO:B0014822 ! KGP1B_HUMAN relationship: has_participant CCO:B0017343 ! Q15300_HUMAN relationship: has_participant CCO:B0021337 ! KAP1_HUMAN relationship: has_participant CCO:B0021338 ! Q8N422_HUMAN relationship: has_participant CCO:B0022454 ! KAP3_HUMAN relationship: has_participant CCO:B0022455 ! KAP2_HUMAN relationship: has_participant CCO:B0022458 ! Q9BUB1_HUMAN relationship: has_participant CCO:B0053748 ! A3R6R8_HUMAN relationship: has_participant CCO:B0054240 ! B1ALS0_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054454 ! NDUS4_HUMAN relationship: has_participant CCO:B0054757 ! RPGF3_HUMAN relationship: has_participant CCO:B0056278 ! GRDN_HUMAN relationship: has_participant CCO:B0056372 ! Q569L6_HUMAN relationship: has_participant CCO:B0056861 ! Q6NUQ6_HUMAN relationship: has_participant CCO:B0058055 ! RPGF4_HUMAN relationship: has_participant CCO:B0059050 ! DAPLE_HUMAN [Term] id: CCO:P0000501 name: negative regulation of protein amino acid phosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to amino acids within a protein." [GOC:hjd] subset: gosubset_prok synonym: "down regulation of protein amino acid phosphorylation" EXACT [] synonym: "down-regulation of protein amino acid phosphorylation" EXACT [] synonym: "downregulation of protein amino acid phosphorylation" EXACT [] synonym: "inhibition of protein amino acid phosphorylation" NARROW [] xref: GO:0001933 is_a: CCO:P0000500 ! regulation of protein amino acid phosphorylation is_a: CCO:P0001434 ! negative regulation of protein modification process is_a: CCO:P0002058 ! negative regulation of phosphorylation relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN [Term] id: CCO:P0000502 name: positive regulation of protein amino acid phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein." [GOC:hjd] subset: gosubset_prok synonym: "activation of protein amino acid phosphorylation" NARROW [] synonym: "stimulation of protein amino acid phosphorylation" NARROW [] synonym: "up regulation of protein amino acid phosphorylation" EXACT [] synonym: "up-regulation of protein amino acid phosphorylation" EXACT [] synonym: "upregulation of protein amino acid phosphorylation" EXACT [] xref: GO:0001934 is_a: CCO:P0000500 ! regulation of protein amino acid phosphorylation is_a: CCO:P0001435 ! positive regulation of protein modification process is_a: CCO:P0002059 ! positive regulation of phosphorylation relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001516 ! BMP4_HUMAN relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001573 ! CCND2_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001995 ! RBCC1_HUMAN relationship: has_participant CCO:B0056340 ! Q503B1_HUMAN relationship: has_participant CCO:B0058002 ! ITLN1_HUMAN relationship: has_participant CCO:B0058558 ! CAR14_HUMAN [Term] id: CCO:P0000503 name: endothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0001935 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0001736 ! DLG1_HUMAN relationship: has_participant CCO:B0054907 ! CALCA_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0055446 ! MMP14_HUMAN [Term] id: CCO:P0000504 name: regulation of endothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." [GOC:add] xref: GO:0001936 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0000503 ! endothelial cell proliferation [Term] id: CCO:P0000505 name: negative regulation of endothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "down regulation of endothelial cell proliferation" EXACT [] synonym: "down-regulation of endothelial cell proliferation" EXACT [] synonym: "downregulation of endothelial cell proliferation" EXACT [] synonym: "inhibition of endothelial cell proliferation" NARROW [] xref: GO:0001937 is_a: CCO:P0000504 ! regulation of endothelial cell proliferation is_a: CCO:P0000817 ! negative regulation of cell proliferation relationship: has_participant CCO:B0001448 ! TNF15_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0005462 ! CAV2_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0005778 ! ATPA_HUMAN relationship: has_participant CCO:B0027467 ! MCA1_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0054945 ! WNT2_HUMAN relationship: has_participant CCO:B0055014 ! SCG2_HUMAN relationship: has_participant CCO:B0058004 ! ASZ1_HUMAN relationship: has_participant CCO:B0058050 ! CTTB2_HUMAN relationship: negatively_regulates CCO:P0000503 ! endothelial cell proliferation [Term] id: CCO:P0000506 name: positive regulation of endothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "activation of endothelial cell proliferation" NARROW [] synonym: "stimulation of endothelial cell proliferation" NARROW [] synonym: "up regulation of endothelial cell proliferation" EXACT [] synonym: "up-regulation of endothelial cell proliferation" EXACT [] synonym: "upregulation of endothelial cell proliferation" EXACT [] xref: GO:0001938 is_a: CCO:P0000504 ! regulation of endothelial cell proliferation is_a: CCO:P0000816 ! positive regulation of cell proliferation relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN relationship: has_participant CCO:B0054484 ! TNF12_HUMAN relationship: has_participant CCO:B0055014 ! SCG2_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0057450 ! AGGF1_HUMAN relationship: positively_regulates CCO:P0000503 ! endothelial cell proliferation [Term] id: CCO:P0000507 name: regulation of cell-matrix adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix." [GOC:hjd] xref: GO:0001952 is_a: CCO:P0001245 ! regulation of cell adhesion relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001610 ! PK3CB_HUMAN relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0055012 ! MYF5_HUMAN [Term] id: CCO:P0000508 name: negative regulation of cell-matrix adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to the extracellular matrix." [GOC:hjd] synonym: "down regulation of cell-matrix adhesion" EXACT [] synonym: "down-regulation of cell-matrix adhesion" EXACT [] synonym: "downregulation of cell-matrix adhesion" EXACT [] synonym: "inhibition of cell-matrix adhesion" NARROW [] xref: GO:0001953 is_a: CCO:P0000507 ! regulation of cell-matrix adhesion is_a: CCO:P0000707 ! negative regulation of cell adhesion relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN [Term] id: CCO:P0000509 name: positive regulation of cell-matrix adhesion namespace: biological_process def: "Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix." [GOC:hjd] synonym: "activation of cell-matrix adhesion" NARROW [] synonym: "stimulation of cell-matrix adhesion" NARROW [] synonym: "up regulation of cell-matrix adhesion" EXACT [] synonym: "up-regulation of cell-matrix adhesion" EXACT [] synonym: "upregulation of cell-matrix adhesion" EXACT [] xref: GO:0001954 is_a: CCO:P0000507 ! regulation of cell-matrix adhesion is_a: CCO:P0002553 ! positive regulation of cell adhesion relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN [Term] id: CCO:P0000510 name: positive regulation of neurotransmitter secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:hjd] synonym: "activation of neurotransmitter secretion" NARROW [] synonym: "stimulation of neurotransmitter secretion" NARROW [] synonym: "up regulation of neurotransmitter secretion" EXACT [] synonym: "up-regulation of neurotransmitter secretion" EXACT [] synonym: "upregulation of neurotransmitter secretion" EXACT [] xref: GO:0001956 is_a: CCO:P0002749 ! regulation of neurotransmitter secretion is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0018239 ! SYUA_HUMAN [Term] id: CCO:P0000511 name: regulation of cytokine and chemokine mediated signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the cytokine and chemokine mediated signaling pathway." [GOC:hjd] synonym: "regulation of cytokine and chemokine mediated signalling pathway" EXACT [] xref: GO:0001959 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: regulates CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:P0000512 name: negative regulation of cytokine and chemokine mediated signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the cytokine and chemokine mediated signaling pathway." [GOC:hjd] synonym: "down regulation of cytokine and chemokine mediated signaling pathway" EXACT [] synonym: "down-regulation of cytokine and chemokine mediated signaling pathway" EXACT [] synonym: "downregulation of cytokine and chemokine mediated signaling pathway" EXACT [] synonym: "inhibition of cytokine and chemokine mediated signaling pathway" NARROW [] synonym: "negative regulation of cytokine and chemokine mediated signalling pathway" EXACT [] xref: GO:0001960 is_a: CCO:P0000511 ! regulation of cytokine and chemokine mediated signaling pathway is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0056756 ! SIGIR_HUMAN relationship: negatively_regulates CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:P0000513 name: positive regulation of cytokine and chemokine mediated signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a cytokine and chemokine mediated signaling pathway." [GOC:hjd] synonym: "activation of cytokine and chemokine mediated signaling pathway" NARROW [] synonym: "positive regulation of cytokine and chemokine mediated signalling pathway" EXACT [] synonym: "stimulation of cytokine and chemokine mediated signaling pathway" NARROW [] synonym: "up regulation of cytokine and chemokine mediated signaling pathway" EXACT [] synonym: "up-regulation of cytokine and chemokine mediated signaling pathway" EXACT [] synonym: "upregulation of cytokine and chemokine mediated signaling pathway" EXACT [] xref: GO:0001961 is_a: CCO:P0000511 ! regulation of cytokine and chemokine mediated signaling pathway is_a: CCO:P0000885 ! positive regulation of signal transduction relationship: positively_regulates CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:P0000514 name: regulation of activation of membrane attack complex namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade." [GOC:hjd] xref: GO:0001969 is_a: CCO:P0001263 ! regulation of complement activation is_a: CCO:P0002051 ! regulation of cytolysis [Term] id: CCO:P0000515 name: positive regulation of activation of membrane attack complex namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade." [GOC:hjd] synonym: "activation of activation of membrane attack complex" NARROW [] synonym: "stimulation of activation of membrane attack complex" NARROW [] synonym: "up regulation of activation of membrane attack complex" EXACT [] synonym: "up-regulation of activation of membrane attack complex" EXACT [] synonym: "upregulation of activation of membrane attack complex" EXACT [] xref: GO:0001970 is_a: CCO:P0000514 ! regulation of activation of membrane attack complex is_a: CCO:P0002612 ! positive regulation of complement activation is_a: CCO:P0002614 ! positive regulation of cytolysis [Term] id: CCO:P0000516 name: negative regulation of activation of membrane attack complex namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade." [GOC:hjd] synonym: "down regulation of activation of membrane attack complex" EXACT [] synonym: "down-regulation of activation of membrane attack complex" EXACT [] synonym: "downregulation of activation of membrane attack complex" EXACT [] synonym: "inhibition of activation of membrane attack complex" NARROW [] xref: GO:0001971 is_a: CCO:P0000514 ! regulation of activation of membrane attack complex is_a: CCO:P0002611 ! negative regulation of complement activation is_a: CCO:P0002613 ! negative regulation of cytolysis [Term] id: CCO:P0000517 name: adenosine receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph] synonym: "adenosine receptor signalling pathway" EXACT [] xref: GO:0001973 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0054773 ! ADCY5_HUMAN relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN [Term] id: CCO:P0000518 name: desensitization of G-protein coupled receptor protein signaling pathway namespace: biological_process def: "The process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity after prolonged stimulation with an agonist of the pathway." [PMID:8396717] synonym: "desensitisation of G-protein coupled receptor protein signalling pathway" EXACT [] xref: GO:0002029 is_a: CCO:P0001236 ! adaptation of signaling pathway is_a: CCO:P0002532 ! negative regulation of G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0055180 ! ARBK1_HUMAN [Term] id: CCO:P0000519 name: inhibitory G-protein coupled receptor phosphorylation namespace: biological_process def: "The process that inhibits the signaling function of a G-protein coupled receptor by addition of a phosphate group to its third intracellular loop consensu thes site." [PMID:8396717] xref: GO:0002030 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000518 ! desensitization of G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0000520 name: G-protein coupled receptor internalization namespace: biological_process def: "The process by which a G-protein coupled receptor is taken up into an endocytic vesicle." [PMID:8396717] xref: GO:0002031 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0020561 ! PLD2_HUMAN relationship: part_of CCO:P0000518 ! desensitization of G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0000521 name: desensitization of G-protein coupled receptor protein signaling pathway by arrestin namespace: biological_process def: "The process that inhibits the signaling function of a G-protein coupled receptor by uncoupling the receptor from its downstream G proteins." [GOC:dph, GOC:tb, PMID:8396717] synonym: "arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway" EXACT [] synonym: "arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway" EXACT [GOC:dph, GOC:tb] synonym: "arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway" EXACT [] xref: GO:0002032 is_a: CCO:P0000518 ! desensitization of G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN [Term] id: CCO:P0000522 name: blood vessel endothelial cell proliferation during sprouting angiogenesis namespace: biological_process def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population during sprouting angiogenesis." [PMID:16391003] xref: GO:0002043 is_a: CCO:P0000503 ! endothelial cell proliferation [Term] id: CCO:P0000523 name: regulation of cell adhesion during intussusceptive angiogenesis namespace: biological_process def: "The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix during intussusceptive angiogenesis." [PMID:16391003] xref: GO:0002045 is_a: CCO:P0001245 ! regulation of cell adhesion [Term] id: CCO:P0000524 name: positive regulation of neuroblast proliferation namespace: biological_process def: "Any process that activates or increases the rate of neuroblast proliferation." [GOC:dph] synonym: "activation of neuroblast proliferation" NARROW [] synonym: "stimulation of neuroblast proliferation" NARROW [] synonym: "up regulation of neuroblast proliferation" EXACT [] synonym: "up-regulation of neuroblast proliferation" EXACT [] synonym: "upregulation of neuroblast proliferation" EXACT [] xref: GO:0002052 is_a: CCO:P0000816 ! positive regulation of cell proliferation relationship: has_participant CCO:B0001635 ! VEGFC_HUMAN relationship: has_participant CCO:B0006039 ! SMO_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056683 ! OTP_HUMAN relationship: positively_regulates CCO:P0000793 ! neuroblast proliferation [Term] id: CCO:P0000525 name: positive regulation of mesenchymal cell proliferation namespace: biological_process def: "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." [GOC:dph] synonym: "activation of mesenchymal cell proliferation" NARROW [] synonym: "stimulation of mesenchymal cell proliferation" NARROW [] synonym: "up regulation of mesenchymal cell proliferation" EXACT [] synonym: "up-regulation of mesenchymal cell proliferation" EXACT [] synonym: "upregulation of mesenchymal cell proliferation" EXACT [] xref: GO:0002053 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0000946 ! regulation of mesenchymal cell proliferation relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0018677 ! TBX18_HUMAN relationship: positively_regulates CCO:P0000945 ! mesenchymal cell proliferation [Term] id: CCO:P0000526 name: regulation of oxidative phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis." [GOC:dph] xref: GO:0002082 is_a: CCO:P0002057 ! regulation of phosphorylation is_a: CCO:P0002217 ! regulation of generation of precursor metabolites and energy relationship: has_participant CCO:B0055732 ! ATP7A_HUMAN [Term] id: CCO:P0000527 name: repression of premature neural plate formation namespace: biological_process def: "The process that prevents cells of the epiblast from differentiating into neuroepithelial cells before the appropriate time." [GOC:dph, PMID:16678814] synonym: "negative regulation of neural plate biosynthesis" EXACT [] synonym: "negative regulation of neural plate formation" EXACT [] xref: GO:0002085 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002851 ! regulation of timing of cell differentiation relationship: has_participant CCO:B0042120 ! NODAL_HUMAN [Term] id: CCO:P0000528 name: regulation of receptor internalization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of receptor internalization." [GOC:hjd] xref: GO:0002090 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process is_a: CCO:P0002801 ! regulation of receptor-mediated endocytosis [Term] id: CCO:P0000529 name: negative regulation of receptor internalization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor internalization." [GOC:hjd] synonym: "down regulation of receptor internalization" EXACT [] synonym: "down-regulation of receptor internalization" EXACT [] synonym: "downregulation of receptor internalization" EXACT [] synonym: "inhibition of receptor internalization" NARROW [] xref: GO:0002091 is_a: CCO:P0000528 ! regulation of receptor internalization is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process is_a: CCO:P0002803 ! negative regulation of receptor-mediated endocytosis [Term] id: CCO:P0000530 name: positive regulation of receptor internalization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of receptor internalization." [GOC:hjd] synonym: "activation of receptor internalization" NARROW [] synonym: "stimulation of receptor internalization" NARROW [] synonym: "up regulation of receptor internalization" EXACT [] synonym: "up-regulation of receptor internalization" EXACT [] synonym: "upregulation of receptor internalization" EXACT [] xref: GO:0002092 is_a: CCO:P0000528 ! regulation of receptor internalization is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process is_a: CCO:P0002802 ! positive regulation of receptor-mediated endocytosis [Term] id: CCO:P0000531 name: innate immune response activating cell surface receptor signaling pathway namespace: biological_process def: "Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15199967] synonym: "activation of innate immune response by cell surface receptor signaling pathway" EXACT [] synonym: "innate immune response activating cell surface receptor signalling pathway" EXACT [] xref: GO:0002220 is_a: CCO:P0000547 ! immune response-activating cell surface receptor signaling pathway is_a: CCO:P0000574 ! innate immune response-activating signal transduction [Term] id: CCO:P0000532 name: pattern recognition receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a cell surface or intracellular pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15199967] synonym: "PAMP receptor signaling pathway" EXACT [ISBN:0781735149 "Fundamental Immunology", PMID:15199967, PMID:15728447] synonym: "pathogen receptor signaling pathway" EXACT [ISBN:0781735149 "Fundamental Immunology", PMID:15199967, PMID:15728447] synonym: "pathogen receptor signalling pathway" EXACT [ISBN:0781735149 "Fundamental Immunology", PMID:15199967, PMID:15728447] synonym: "PRR signaling pathway" EXACT [ISBN:0781735149 "Fundamental Immunology", PMID:15199967, PMID:15728447] xref: GO:0002221 is_a: CCO:P0000574 ! innate immune response-activating signal transduction [Term] id: CCO:P0000533 name: stimulatory killer cell immunoglobulin-like receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a killer cell immunoglobulin-like receptor capable of cellular activation." [GOC:add, GOC:mtg_15nov05, ISBN:0781735149 "Fundamental Immunology"] comment: This term was added by GO_REF:0000022. synonym: "stimulatory killer cell immunoglobulin-like receptor signalling pathway" EXACT [] synonym: "stimulatory KIR signaling pathway" EXACT [ISBN:0781735149 "Fundamental Immunology"] xref: GO:0002222 is_a: CCO:P0000531 ! innate immune response activating cell surface receptor signaling pathway [Term] id: CCO:P0000534 name: stimulatory C-type lectin receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation." [GOC:add, GOC:mtg_15nov05, ISBN:0781735149 "Fundamental Immunology"] comment: This term was added by GO_REF:0000022. synonym: "stimulatory C-type lectin receptor signalling pathway" EXACT [] synonym: "stimulatory Ly49 family receptor signaling pathway." NARROW [ISBN:0781735149 "Fundamental Immunology"] xref: GO:0002223 is_a: CCO:P0000531 ! innate immune response activating cell surface receptor signaling pathway relationship: has_participant CCO:B0055192 ! NKG2D_HUMAN relationship: has_participant CCO:B0056200 ! MICA_HUMAN [Term] id: CCO:P0000535 name: toll-like receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:add, GOC:mtg_15nov05, ISBN:0781735149 "Fundamental Immunology", PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] comment: This term was added by GO_REF:0000022. Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses. synonym: "TLR signaling pathway" EXACT [ISBN:0781735149 "Fundamental Immunology"] synonym: "toll-like receptor signalling pathway" EXACT [] xref: GO:0002224 is_a: CCO:P0000532 ! pattern recognition receptor signaling pathway relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0058795 ! NOD2_HUMAN [Term] id: CCO:P0000536 name: detection of endoplasmic reticulum overloading namespace: biological_process def: "The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal." [GOC:add, PMID:10390516] synonym: "detection of ER overloading" EXACT [] xref: GO:0002234 is_a: CCO:P0000684 ! ER overload response [Term] id: CCO:P0000537 name: NK T cell proliferation during immune response namespace: biological_process def: "The expansion of a NK T cell population by cell division during an immune response." [GOC:add, PMID:15771592] synonym: "natural killer T lymphocyte proliferation during immune response" EXACT [] synonym: "natural killer T-cell proliferation during immune response" EXACT [] synonym: "natural killer T-lymphocyte proliferation during immune response" EXACT [] synonym: "NK T lymphocyte proliferation during immune response" EXACT [] synonym: "NK T-cell proliferation during immune response" EXACT [] synonym: "NK T-lymphocyte proliferation during immune response" EXACT [] xref: GO:0002289 is_a: CCO:P0000482 ! NK T cell proliferation is_a: CCO:P0000539 ! alpha-beta T cell proliferation during immune response [Term] id: CCO:P0000538 name: T cell proliferation during immune response namespace: biological_process def: "The expansion of a T cell population by cell division during an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "T lymphocyte proliferation during immune response" EXACT [] synonym: "T-cell proliferation during immune response" EXACT [] synonym: "T-lymphocyte proliferation during immune response" EXACT [] xref: GO:0002309 is_a: CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0000539 name: alpha-beta T cell proliferation during immune response namespace: biological_process def: "The expansion of an alpha-beta T cell population by cell division during an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "alpha-beta T lymphocyte proliferation during immune response" EXACT [] synonym: "alpha-beta T-cell proliferation during immune response" EXACT [] synonym: "alpha-beta T-lymphocyte proliferation during immune response" EXACT [] xref: GO:0002310 is_a: CCO:P0000538 ! T cell proliferation during immune response is_a: CCO:P0002708 ! alpha-beta T cell proliferation [Term] id: CCO:P0000540 name: gamma-delta T cell proliferation during immune response namespace: biological_process def: "The expansion of an gamma-delta T cell population by cell division during an immune response." [GOC:add] synonym: "gamma-delta T lymphocyte proliferation during immune response" EXACT [] synonym: "gamma-delta T-cell proliferation during immune response" EXACT [] synonym: "gamma-delta T-lymphocyte proliferation during immune response" EXACT [] xref: GO:0002311 is_a: CCO:P0000538 ! T cell proliferation during immune response is_a: CCO:P0002707 ! gamma-delta T cell proliferation [Term] id: CCO:P0000541 name: B cell proliferation during immune response namespace: biological_process def: "The expansion of a B cell population by cell division following B cell activation during an immune response." [GOC:jal] synonym: "B lymphocyte proliferation during immune response" EXACT [] synonym: "B-cell proliferation during immune response" EXACT [] synonym: "B-lymphocyte proliferation during immune response" EXACT [] xref: GO:0002322 is_a: CCO:P0002040 ! B cell proliferation [Term] id: CCO:P0000542 name: natural killer cell proliferation during immune response namespace: biological_process def: "The expansion of a natural killer cell population by cell division during an immune response." [GOC:add, PMID:15032583] synonym: "NK cell proliferation during immune response" EXACT [] xref: GO:0002324 is_a: CCO:P0000471 ! natural killer cell proliferation [Term] id: CCO:P0000543 name: B cell homeostatic proliferation namespace: biological_process def: "The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus." [GOC:jal] synonym: "B lymphocyte homeostatic proliferation" EXACT [] synonym: "B-cell homeostatic proliferation" EXACT [] synonym: "B-lymphocyte homeostatic proliferation" EXACT [] xref: GO:0002358 is_a: CCO:P0002040 ! B cell proliferation [Term] id: CCO:P0000544 name: B-1 B cell proliferation namespace: biological_process def: "The expansion of a B-1 B cell by cell division. Follows B cell activation." [GOC:jal] synonym: "B-1 B lymphocyte proliferation" EXACT [] synonym: "B-1 B-cell proliferation" EXACT [] synonym: "B-1 B-lymphocyte proliferation" EXACT [] xref: GO:0002359 is_a: CCO:P0002040 ! B cell proliferation [Term] id: CCO:P0000545 name: T cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:16730260] comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell. synonym: "T lymphocyte mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "T-cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "T-lymphocyte mediated cytotoxicity directed against tumor cell target" EXACT [] xref: GO:0002419 is_a: CCO:P0000487 ! T cell mediated cytotoxicity [Term] id: CCO:P0000546 name: natural killer cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:16730260] comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell. synonym: "NK cell mediated cytotoxicity directed against tumor cell target" EXACT [] xref: GO:0002420 is_a: CCO:P0002050 ! natural killer cell mediated cytotoxicity [Term] id: CCO:P0000547 name: immune response-activating cell surface receptor signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response." [GOC:add, GOC:mtg_15nov05, ISBN:0781735149 "Fundamental Immunology"] comment: This term was added by GO_REF:0000022. synonym: "activation of immune response by cell surface receptor signaling pathway" EXACT [] synonym: "immune response-activating cell surface receptor signalling pathway" EXACT [] xref: GO:0002429 is_a: CCO:P0000573 ! immune response-activating signal transduction is_a: CCO:P0000582 ! immune response-regulating cell surface receptor signaling pathway relationship: has_participant CCO:B0056199 ! MICB_HUMAN [Term] id: CCO:P0000548 name: complement receptor mediated signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway." [GOC:add, GOC:mtg_15nov05, ISBN:0781735149 "Fundamental Immunology"] comment: This term was added by GO_REF:0000022. synonym: "complement receptor mediated signalling pathway" EXACT [] synonym: "immune response-regulating cell surface receptor signalling pathway" BROAD [] xref: GO:0002430 is_a: CCO:P0000547 ! immune response-activating cell surface receptor signaling pathway [Term] id: CCO:P0000549 name: Fc receptor mediated stimulatory signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:add, GOC:mtg_15nov05, ISBN:0781735149 "Fundamental Immunology"] comment: This term was added by GO_REF:0000022. synonym: "Fc receptor mediated stimulatory signalling pathway" EXACT [] xref: GO:0002431 is_a: CCO:P0000547 ! immune response-activating cell surface receptor signaling pathway relationship: has_participant CCO:B0055217 ! FCERG_HUMAN [Term] id: CCO:P0000550 name: regulation of proteolysis associated with antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation." [GOC:add] xref: GO:0002628 is_a: CCO:P0001246 ! regulation of proteolysis is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0000551 name: negative regulation of proteolysis associated with antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation." [GOC:add] synonym: "down regulation of proteolysis associated with antigen processing and presentation" EXACT [] synonym: "down-regulation of proteolysis associated with antigen processing and presentation" EXACT [] synonym: "downregulation of proteolysis associated with antigen processing and presentation" EXACT [] synonym: "inhibition of proteolysis associated with antigen processing and presentation" NARROW [] xref: GO:0002629 is_a: CCO:P0000550 ! regulation of proteolysis associated with antigen processing and presentation is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0002578 ! negative regulation of proteolysis [Term] id: CCO:P0000552 name: positive regulation of proteolysis associated with antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation." [GOC:add] synonym: "activation of proteolysis associated with antigen processing and presentation" NARROW [] synonym: "stimulation of proteolysis associated with antigen processing and presentation" NARROW [] synonym: "up regulation of proteolysis associated with antigen processing and presentation" EXACT [] synonym: "up-regulation of proteolysis associated with antigen processing and presentation" EXACT [] synonym: "upregulation of proteolysis associated with antigen processing and presentation" EXACT [] xref: GO:0002630 is_a: CCO:P0000550 ! regulation of proteolysis associated with antigen processing and presentation is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0002579 ! positive regulation of proteolysis [Term] id: CCO:P0000553 name: regulation of leukocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "regulation of immune cell migration" EXACT [] synonym: "regulation of leucocyte migration" EXACT [] xref: GO:0002685 is_a: CCO:P0001257 ! regulation of cell migration [Term] id: CCO:P0000554 name: negative regulation of leukocyte migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "down regulation of leukocyte migration" EXACT [] synonym: "down-regulation of leukocyte migration" EXACT [] synonym: "downregulation of leukocyte migration" EXACT [] synonym: "inhibition of leukocyte migration" NARROW [] synonym: "negative regulation of immune cell migration" EXACT [] synonym: "negative regulation of leucocyte migration" EXACT [] xref: GO:0002686 is_a: CCO:P0000553 ! regulation of leukocyte migration is_a: CCO:P0001259 ! negative regulation of cell migration relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN [Term] id: CCO:P0000555 name: positive regulation of leukocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "activation of leukocyte migration" NARROW [] synonym: "positive regulation of immune cell migration" EXACT [] synonym: "positive regulation of leucocyte migration" EXACT [] synonym: "stimulation of leukocyte migration" NARROW [] synonym: "up regulation of leukocyte migration" EXACT [] synonym: "up-regulation of leukocyte migration" EXACT [] synonym: "upregulation of leukocyte migration" EXACT [] xref: GO:0002687 is_a: CCO:P0000553 ! regulation of leukocyte migration is_a: CCO:P0001258 ! positive regulation of cell migration relationship: has_participant CCO:B0056463 ! MIA3_HUMAN [Term] id: CCO:P0000556 name: regulation of leukocyte chemotaxis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis." [GOC:add] synonym: "regulation of immune cell chemotaxis" EXACT [] synonym: "regulation of leucocyte chemotaxis" EXACT [] xref: GO:0002688 is_a: CCO:P0000553 ! regulation of leukocyte migration [Term] id: CCO:P0000557 name: negative regulation of leukocyte chemotaxis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis." [GOC:add] synonym: "down regulation of leukocyte chemotaxis" EXACT [] synonym: "down-regulation of leukocyte chemotaxis" EXACT [] synonym: "downregulation of leukocyte chemotaxis" EXACT [] synonym: "inhibition of leukocyte chemotaxis" NARROW [] synonym: "negative regulation of immune cell chemotaxis" EXACT [] synonym: "negative regulation of leucocyte chemotaxis" EXACT [] xref: GO:0002689 is_a: CCO:P0000554 ! negative regulation of leukocyte migration is_a: CCO:P0000556 ! regulation of leukocyte chemotaxis [Term] id: CCO:P0000558 name: positive regulation of leukocyte chemotaxis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis." [GOC:add] synonym: "activation of leukocyte chemotaxis" NARROW [] synonym: "positive regulation of immune cell chemotaxis" EXACT [] synonym: "positive regulation of leucocyte chemotaxis" EXACT [] synonym: "stimulation of leukocyte chemotaxis" NARROW [] synonym: "up regulation of leukocyte chemotaxis" EXACT [] synonym: "up-regulation of leukocyte chemotaxis" EXACT [] synonym: "upregulation of leukocyte chemotaxis" EXACT [] xref: GO:0002690 is_a: CCO:P0000555 ! positive regulation of leukocyte migration is_a: CCO:P0000556 ! regulation of leukocyte chemotaxis [Term] id: CCO:P0000559 name: regulation of cellular extravasation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of cellular extravasation." [GOC:add] xref: GO:0002691 is_a: CCO:P0000553 ! regulation of leukocyte migration [Term] id: CCO:P0000560 name: negative regulation of cellular extravasation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation." [GOC:add] synonym: "down regulation of cellular extravasation" EXACT [] synonym: "down-regulation of cellular extravasation" EXACT [] synonym: "downregulation of cellular extravasation" EXACT [] synonym: "inhibition of cellular extravasation" NARROW [] xref: GO:0002692 is_a: CCO:P0000554 ! negative regulation of leukocyte migration is_a: CCO:P0000559 ! regulation of cellular extravasation [Term] id: CCO:P0000561 name: positive regulation of cellular extravasation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of cellular extravasation." [GOC:add] synonym: "activation of cellular extravasation" NARROW [] synonym: "stimulation of cellular extravasation" NARROW [] synonym: "up regulation of cellular extravasation" EXACT [] synonym: "up-regulation of cellular extravasation" EXACT [] synonym: "upregulation of cellular extravasation" EXACT [] xref: GO:0002693 is_a: CCO:P0000555 ! positive regulation of leukocyte migration is_a: CCO:P0000559 ! regulation of cellular extravasation [Term] id: CCO:P0000562 name: regulation of leukocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "regulation of immune cell activation" EXACT [] synonym: "regulation of leucocyte activation" EXACT [] xref: GO:0002694 is_a: CCO:P0002983 ! regulation of cell activation [Term] id: CCO:P0000563 name: negative regulation of leukocyte activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "down regulation of leukocyte activation" EXACT [] synonym: "down-regulation of leukocyte activation" EXACT [] synonym: "downregulation of leukocyte activation" EXACT [] synonym: "inhibition of leukocyte activation" NARROW [] synonym: "negative regulation of immune cell activation" EXACT [] synonym: "negative regulation of leucocyte activation" EXACT [] xref: GO:0002695 is_a: CCO:P0000562 ! regulation of leukocyte activation is_a: CCO:P0002984 ! negative regulation of cell activation [Term] id: CCO:P0000564 name: positive regulation of leukocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "activation of leukocyte activation" NARROW [] synonym: "positive regulation of immune cell activation" EXACT [] synonym: "positive regulation of leucocyte activation" EXACT [] synonym: "stimulation of leukocyte activation" NARROW [] synonym: "up regulation of leukocyte activation" EXACT [] synonym: "up-regulation of leukocyte activation" EXACT [] synonym: "upregulation of leukocyte activation" EXACT [] xref: GO:0002696 is_a: CCO:P0000562 ! regulation of leukocyte activation is_a: CCO:P0002985 ! positive regulation of cell activation [Term] id: CCO:P0000565 name: regulation of cytokine biosynthetic process during immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of cytokine biosynthesis during immune response." [GOC:add] xref: GO:0002742 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0000566 name: negative regulation of cytokine biosynthetic process during immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine biosynthesis during immune response." [GOC:add] synonym: "down regulation of cytokine biosynthetic process during immune response" EXACT [] synonym: "down-regulation of cytokine biosynthetic process during immune response" EXACT [] synonym: "downregulation of cytokine biosynthetic process during immune response" EXACT [] synonym: "inhibition of cytokine biosynthetic process during immune response" NARROW [] xref: GO:0002743 is_a: CCO:P0000565 ! regulation of cytokine biosynthetic process during immune response is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process [Term] id: CCO:P0000567 name: positive regulation of cytokine biosynthetic process during immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of cytokine biosynthesis during immune response." [GOC:add] synonym: "activation of cytokine biosynthetic process during immune response" NARROW [] synonym: "stimulation of cytokine biosynthetic process during immune response" NARROW [] synonym: "up regulation of cytokine biosynthetic process during immune response" EXACT [] synonym: "up-regulation of cytokine biosynthetic process during immune response" EXACT [] synonym: "upregulation of cytokine biosynthetic process during immune response" EXACT [] xref: GO:0002744 is_a: CCO:P0000565 ! regulation of cytokine biosynthetic process during immune response is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process [Term] id: CCO:P0000568 name: cell surface pattern recognition receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a cell surface pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15199967] synonym: "cell surface PAMP receptor signaling pathway" EXACT [] synonym: "cell surface pathogen receptor signaling pathway" EXACT [] synonym: "cell surface pattern recognition receptor signalling pathway" EXACT [] synonym: "cell surface PRR signaling pathway" EXACT [] xref: GO:0002752 is_a: CCO:P0000531 ! innate immune response activating cell surface receptor signaling pathway is_a: CCO:P0000532 ! pattern recognition receptor signaling pathway relationship: has_participant CCO:B0030171 ! TLR2_HUMAN [Term] id: CCO:P0000569 name: cytoplasmic pattern recognition receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a cytoplasmic pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15199967] synonym: "cytoplasmic PAMP receptor signaling pathway" EXACT [] synonym: "cytoplasmic pathogen receptor signaling pathway" EXACT [] synonym: "cytoplasmic pattern recognition receptor signalling pathway" EXACT [] synonym: "cytoplasmic PRR signaling pathway" EXACT [] xref: GO:0002753 is_a: CCO:P0000532 ! pattern recognition receptor signaling pathway [Term] id: CCO:P0000570 name: intracellular vesicle pattern recognition receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a pattern recognition receptor (PRR) located within the membrane of an intracellular vesicle such as an endosome or lysosome. Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15199967] synonym: "intracellular vesicle PAMP receptor signaling pathway" EXACT [] synonym: "intracellular vesicle pathogen receptor signaling pathway" EXACT [] synonym: "intracellular vesicle pattern recognition receptor signalling pathway" EXACT [] synonym: "intracellular vesicle PRR signaling pathway" EXACT [] xref: GO:0002754 is_a: CCO:P0000532 ! pattern recognition receptor signaling pathway [Term] id: CCO:P0000571 name: MyD88-dependent toll-like receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor and relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] synonym: "MyD88-dependent TLR signaling pathway" EXACT [] synonym: "MyD88-dependent toll-like receptor signalling pathway" EXACT [] xref: GO:0002755 is_a: CCO:P0000535 ! toll-like receptor signaling pathway relationship: has_participant CCO:B0030171 ! TLR2_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:P0000572 name: MyD88-independent toll-like receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:12467241, PMID:12524386, PMID:12855817, PMID:15585605, PMID:15728447] synonym: "MyD88-independent TLR signaling pathway" EXACT [] synonym: "MyD88-independent toll-like receptor signalling pathway" EXACT [] xref: GO:0002756 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0000573 name: immune response-activating signal transduction namespace: biological_process def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response." [GOC:add] xref: GO:0002757 is_a: CCO:P0000578 ! immune response-regulating signal transduction [Term] id: CCO:P0000574 name: innate immune response-activating signal transduction namespace: biological_process def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response." [GOC:add, GOC:mtg_15nov05] comment: This term was added by GO_REF:0000022. xref: GO:0002758 is_a: CCO:P0000573 ! immune response-activating signal transduction [Term] id: CCO:P0000575 name: regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] xref: GO:0002761 is_a: CCO:P0002451 ! regulation of myeloid cell differentiation [Term] id: CCO:P0000576 name: negative regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "down regulation of myeloid leukocyte differentiation" EXACT [] synonym: "down-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "downregulation of myeloid leukocyte differentiation" EXACT [] synonym: "inhibition of myeloid leukocyte differentiation" NARROW [] xref: GO:0002762 is_a: CCO:P0000575 ! regulation of myeloid leukocyte differentiation is_a: CCO:P0002452 ! negative regulation of myeloid cell differentiation [Term] id: CCO:P0000577 name: positive regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "activation of myeloid leukocyte differentiation" NARROW [] synonym: "stimulation of myeloid leukocyte differentiation" NARROW [] synonym: "up regulation of myeloid leukocyte differentiation" EXACT [] synonym: "up-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "upregulation of myeloid leukocyte differentiation" EXACT [] xref: GO:0002763 is_a: CCO:P0000575 ! regulation of myeloid leukocyte differentiation is_a: CCO:P0002453 ! positive regulation of myeloid cell differentiation [Term] id: CCO:P0000578 name: immune response-regulating signal transduction namespace: biological_process def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15771571] xref: GO:0002764 is_a: CCO:P0000708 ! signal transduction [Term] id: CCO:P0000579 name: immune response-inhibiting signal transduction namespace: biological_process def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0002765 is_a: CCO:P0000578 ! immune response-regulating signal transduction [Term] id: CCO:P0000580 name: innate immune response-inhibiting signal transduction namespace: biological_process def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15771571] xref: GO:0002766 is_a: CCO:P0000579 ! immune response-inhibiting signal transduction [Term] id: CCO:P0000581 name: immune response-inhibiting cell surface receptor signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15771571] synonym: "immune response-inhibiting cell surface receptor signalling pathway" EXACT [] xref: GO:0002767 is_a: CCO:P0000579 ! immune response-inhibiting signal transduction is_a: CCO:P0000582 ! immune response-regulating cell surface receptor signaling pathway [Term] id: CCO:P0000582 name: immune response-regulating cell surface receptor signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15771571] synonym: "immune response-regulating cell surface receptor signalling pathway" EXACT [] xref: GO:0002768 is_a: CCO:P0000578 ! immune response-regulating signal transduction is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0055177 ! CD24_HUMAN [Term] id: CCO:P0000583 name: natural killer cell inhibitory signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15771571] synonym: "inhibitory KIR signaling pathway" NARROW [] synonym: "killer cell inhibitory receptor signaling pathway" NARROW [] synonym: "Ly49 inhibitory receptor signaling pathway" NARROW [] synonym: "natural killer cell inhibitory signalling pathway" EXACT [] synonym: "NK cell inhibitory signaling pathway" EXACT [] xref: GO:0002769 is_a: CCO:P0000581 ! immune response-inhibiting cell surface receptor signaling pathway [Term] id: CCO:P0000584 name: T cell inhibitory signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, PMID:15258309] synonym: "T cell inhibitory signalling pathway" EXACT [] synonym: "T lymphocyte inhibitory signaling pathway" EXACT [] synonym: "T-cell inhibitory signaling pathway" EXACT [] synonym: "T-lymphocyte inhibitory signaling pathway" EXACT [] xref: GO:0002770 is_a: CCO:P0000581 ! immune response-inhibiting cell surface receptor signaling pathway [Term] id: CCO:P0000585 name: inhibitory killer cell immunoglobulin-like receptor signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15771571] synonym: "inhibitory killer cell immunoglobulin-like receptor signalling pathway" EXACT [] synonym: "killer cell inhibitory receptor signaling pathway" EXACT [] synonym: "KIR signaling pathway" EXACT [] xref: GO:0002771 is_a: CCO:P0000581 ! immune response-inhibiting cell surface receptor signaling pathway [Term] id: CCO:P0000586 name: inhibitory C-type lectin receptor signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:15771571] synonym: "inhibitory C-type lectin receptor signalling pathway" EXACT [] synonym: "Ly49 inhibitory receptor signaling pathway" NARROW [] xref: GO:0002772 is_a: CCO:P0000581 ! immune response-inhibiting cell surface receptor signaling pathway [Term] id: CCO:P0000587 name: B cell inhibitory signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response." [GOC:add, PMID:16413920] synonym: "B cell inhibitory signalling pathway" EXACT [] synonym: "B lymphocyte inhibitory signaling pathwayBT-lymphocyte inhibitory signaling pathway" EXACT [] synonym: "B-cell inhibitory signaling pathway" EXACT [] xref: GO:0002773 is_a: CCO:P0000581 ! immune response-inhibiting cell surface receptor signaling pathway [Term] id: CCO:P0000588 name: Fc receptor mediated inhibitory signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "Fc receptor mediated inhibitory signalling pathway" EXACT [] xref: GO:0002774 is_a: CCO:P0000581 ! immune response-inhibiting cell surface receptor signaling pathway [Term] id: CCO:P0000589 name: regulation of antimicrobial peptide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis." [GOC:add] xref: GO:0002805 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000590 name: negative regulation of antimicrobial peptide biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis." [GOC:add] synonym: "down regulation of antimicrobial peptide biosynthetic process" EXACT [] synonym: "down-regulation of antimicrobial peptide biosynthetic process" EXACT [] synonym: "downregulation of antimicrobial peptide biosynthetic process" EXACT [] synonym: "inhibition of antimicrobial peptide biosynthetic process" NARROW [] xref: GO:0002806 is_a: CCO:P0000589 ! regulation of antimicrobial peptide biosynthetic process is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process [Term] id: CCO:P0000591 name: positive regulation of antimicrobial peptide biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis." [GOC:add] synonym: "activation of antimicrobial peptide biosynthetic process" NARROW [] synonym: "stimulation of antimicrobial peptide biosynthetic process" NARROW [] synonym: "up regulation of antimicrobial peptide biosynthetic process" EXACT [] synonym: "up-regulation of antimicrobial peptide biosynthetic process" EXACT [] synonym: "upregulation of antimicrobial peptide biosynthetic process" EXACT [] xref: GO:0002807 is_a: CCO:P0000589 ! regulation of antimicrobial peptide biosynthetic process is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process [Term] id: CCO:P0000592 name: regulation of antibacterial peptide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis." [GOC:add] xref: GO:0002808 is_a: CCO:P0000589 ! regulation of antimicrobial peptide biosynthetic process [Term] id: CCO:P0000593 name: negative regulation of antibacterial peptide biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis." [GOC:add] synonym: "down regulation of antibacterial peptide biosynthetic process" EXACT [] synonym: "down-regulation of antibacterial peptide biosynthetic process" EXACT [] synonym: "downregulation of antibacterial peptide biosynthetic process" EXACT [] synonym: "inhibition of antibacterial peptide biosynthetic process" NARROW [] xref: GO:0002809 is_a: CCO:P0000590 ! negative regulation of antimicrobial peptide biosynthetic process is_a: CCO:P0000592 ! regulation of antibacterial peptide biosynthetic process [Term] id: CCO:P0000594 name: regulation of antifungal peptide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis." [GOC:add] xref: GO:0002810 is_a: CCO:P0000589 ! regulation of antimicrobial peptide biosynthetic process [Term] id: CCO:P0000595 name: negative regulation of antifungal peptide biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis." [GOC:add] synonym: "down regulation of antifungal peptide biosynthetic process" EXACT [] synonym: "down-regulation of antifungal peptide biosynthetic process" EXACT [] synonym: "downregulation of antifungal peptide biosynthetic process" EXACT [] synonym: "inhibition of antifungal peptide biosynthetic process" NARROW [] xref: GO:0002811 is_a: CCO:P0000590 ! negative regulation of antimicrobial peptide biosynthetic process is_a: CCO:P0000594 ! regulation of antifungal peptide biosynthetic process [Term] id: CCO:P0000596 name: regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria." [GOC:add] xref: GO:0002813 is_a: CCO:P0000592 ! regulation of antibacterial peptide biosynthetic process [Term] id: CCO:P0000597 name: negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria." [GOC:add] synonym: "down regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] synonym: "down-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] synonym: "downregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] synonym: "inhibition of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" NARROW [] xref: GO:0002814 is_a: CCO:P0000593 ! negative regulation of antibacterial peptide biosynthetic process is_a: CCO:P0000596 ! regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [Term] id: CCO:P0000598 name: regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria." [GOC:add] xref: GO:0002816 is_a: CCO:P0000592 ! regulation of antibacterial peptide biosynthetic process [Term] id: CCO:P0000599 name: negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria." [GOC:add] synonym: "down regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] synonym: "down-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] synonym: "downregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] synonym: "inhibition of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" NARROW [] xref: GO:0002817 is_a: CCO:P0000593 ! negative regulation of antibacterial peptide biosynthetic process is_a: CCO:P0000598 ! regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [Term] id: CCO:P0000600 name: regulation of T cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target." [GOC:add] xref: GO:0002852 is_a: CCO:P0000488 ! regulation of T cell mediated cytotoxicity relationship: regulates CCO:P0000545 ! T cell mediated cytotoxicity directed against tumor cell target [Term] id: CCO:P0000601 name: negative regulation of T cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target." [GOC:add] synonym: "down regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "down-regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "downregulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "inhibition of T cell mediated cytotoxicity directed against tumor cell target" NARROW [] xref: GO:0002853 is_a: CCO:P0000489 ! negative regulation of T cell mediated cytotoxicity is_a: CCO:P0000600 ! regulation of T cell mediated cytotoxicity directed against tumor cell target relationship: negatively_regulates CCO:P0000545 ! T cell mediated cytotoxicity directed against tumor cell target [Term] id: CCO:P0000602 name: positive regulation of T cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target." [GOC:add] synonym: "activation of T cell mediated cytotoxicity directed against tumor cell target" NARROW [] synonym: "stimulation of T cell mediated cytotoxicity directed against tumor cell target" NARROW [] synonym: "up regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "up-regulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "upregulation of T cell mediated cytotoxicity directed against tumor cell target" EXACT [] xref: GO:0002854 is_a: CCO:P0000490 ! positive regulation of T cell mediated cytotoxicity is_a: CCO:P0000600 ! regulation of T cell mediated cytotoxicity directed against tumor cell target relationship: positively_regulates CCO:P0000545 ! T cell mediated cytotoxicity directed against tumor cell target [Term] id: CCO:P0000603 name: regulation of natural killer cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target." [GOC:add] xref: GO:0002858 is_a: CCO:P0002052 ! regulation of natural killer cell mediated cytotoxicity relationship: regulates CCO:P0000546 ! natural killer cell mediated cytotoxicity directed against tumor cell target [Term] id: CCO:P0000604 name: negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target." [GOC:add] synonym: "down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target" NARROW [] xref: GO:0002859 is_a: CCO:P0000603 ! regulation of natural killer cell mediated cytotoxicity directed against tumor cell target is_a: CCO:P0002636 ! negative regulation of natural killer cell mediated cytotoxicity relationship: negatively_regulates CCO:P0000546 ! natural killer cell mediated cytotoxicity directed against tumor cell target [Term] id: CCO:P0000605 name: positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target." [GOC:add] synonym: "activation of natural killer cell mediated cytotoxicity directed against tumor cell target" NARROW [] synonym: "stimulation of natural killer cell mediated cytotoxicity directed against tumor cell target" NARROW [] synonym: "up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] synonym: "upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target" EXACT [] xref: GO:0002860 is_a: CCO:P0000603 ! regulation of natural killer cell mediated cytotoxicity directed against tumor cell target is_a: CCO:P0002637 ! positive regulation of natural killer cell mediated cytotoxicity relationship: has_participant CCO:B0015065 ! CRTAM_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: positively_regulates CCO:P0000546 ! natural killer cell mediated cytotoxicity directed against tumor cell target [Term] id: CCO:P0000606 name: regulation of B cell deletion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of B cell deletion." [GOC:add] synonym: "regulation of B lymphocyte deletion" EXACT [] synonym: "regulation of B-cell deletion" EXACT [] synonym: "regulation of B-lymphocyte deletion" EXACT [] xref: GO:0002867 is_a: CCO:P0000612 ! regulation of B cell apoptosis [Term] id: CCO:P0000607 name: negative regulation of B cell deletion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion." [GOC:add] synonym: "down regulation of B cell deletion" EXACT [] synonym: "down-regulation of B cell deletion" EXACT [] synonym: "downregulation of B cell deletion" EXACT [] synonym: "inhibition of B cell deletion" NARROW [] synonym: "negative regulation of B lymphocyte deletion" EXACT [] synonym: "negative regulation of B-cell deletion" EXACT [] synonym: "negative regulation of B-lymphocyte deletion" EXACT [] xref: GO:0002868 is_a: CCO:P0000606 ! regulation of B cell deletion is_a: CCO:P0000613 ! negative regulation of B cell apoptosis [Term] id: CCO:P0000608 name: positive regulation of B cell deletion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of B cell deletion." [GOC:add] synonym: "activation of B cell deletion" NARROW [] synonym: "positive regulation of B lymphocyte deletion" EXACT [] synonym: "positive regulation of B-cell deletion" EXACT [] synonym: "positive regulation of B-lymphocyte deletion" EXACT [] synonym: "stimulation of B cell deletion" NARROW [] synonym: "up regulation of B cell deletion" EXACT [] synonym: "up-regulation of B cell deletion" EXACT [] synonym: "upregulation of B cell deletion" EXACT [] xref: GO:0002869 is_a: CCO:P0000606 ! regulation of B cell deletion is_a: CCO:P0000614 ! positive regulation of B cell apoptosis [Term] id: CCO:P0000609 name: regulation of central B cell deletion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of central B cell deletion." [GOC:add] xref: GO:0002898 is_a: CCO:P0000606 ! regulation of B cell deletion [Term] id: CCO:P0000610 name: negative regulation of central B cell deletion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion." [GOC:add] synonym: "down regulation of central B cell deletion" EXACT [] synonym: "down-regulation of central B cell deletion" EXACT [] synonym: "downregulation of central B cell deletion" EXACT [] synonym: "inhibition of central B cell deletion" NARROW [] xref: GO:0002899 is_a: CCO:P0000607 ! negative regulation of B cell deletion is_a: CCO:P0000609 ! regulation of central B cell deletion [Term] id: CCO:P0000611 name: positive regulation of central B cell deletion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of central B cell deletion." [GOC:add] synonym: "activation of central B cell deletion" NARROW [] synonym: "stimulation of central B cell deletion" NARROW [] synonym: "up regulation of central B cell deletion" EXACT [] synonym: "up-regulation of central B cell deletion" EXACT [] synonym: "upregulation of central B cell deletion" EXACT [] xref: GO:0002900 is_a: CCO:P0000608 ! positive regulation of B cell deletion is_a: CCO:P0000609 ! regulation of central B cell deletion [Term] id: CCO:P0000612 name: regulation of B cell apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of B cell apoptosis." [GOC:add] xref: GO:0002902 is_a: CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:P0000613 name: negative regulation of B cell apoptosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptosis." [GOC:add] synonym: "down regulation of B cell apoptosis" EXACT [] synonym: "down-regulation of B cell apoptosis" EXACT [] synonym: "downregulation of B cell apoptosis" EXACT [] synonym: "inhibition of B cell apoptosis" NARROW [] xref: GO:0002903 is_a: CCO:P0000612 ! regulation of B cell apoptosis is_a: CCO:P0002148 ! negative regulation of apoptosis relationship: has_participant CCO:B0001603 ! BCL6_HUMAN [Term] id: CCO:P0000614 name: positive regulation of B cell apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of B cell apoptosis." [GOC:add] synonym: "activation of B cell apoptosis" NARROW [] synonym: "stimulation of B cell apoptosis" NARROW [] synonym: "up regulation of B cell apoptosis" EXACT [] synonym: "up-regulation of B cell apoptosis" EXACT [] synonym: "upregulation of B cell apoptosis" EXACT [] xref: GO:0002904 is_a: CCO:P0000612 ! regulation of B cell apoptosis is_a: CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:P0000615 name: regulation of mature B cell apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of mature B cell apoptosis." [GOC:add] xref: GO:0002905 is_a: CCO:P0000612 ! regulation of B cell apoptosis [Term] id: CCO:P0000616 name: negative regulation of mature B cell apoptosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptosis." [GOC:add] synonym: "down regulation of mature B cell apoptosis" EXACT [] synonym: "down-regulation of mature B cell apoptosis" EXACT [] synonym: "downregulation of mature B cell apoptosis" EXACT [] synonym: "inhibition of mature B cell apoptosis" NARROW [] xref: GO:0002906 is_a: CCO:P0000613 ! negative regulation of B cell apoptosis is_a: CCO:P0000615 ! regulation of mature B cell apoptosis relationship: has_participant CCO:B0001458 ! BCL10_HUMAN [Term] id: CCO:P0000617 name: positive regulation of mature B cell apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of mature B cell apoptosis." [GOC:add] synonym: "activation of mature B cell apoptosis" NARROW [] synonym: "stimulation of mature B cell apoptosis" NARROW [] synonym: "up regulation of mature B cell apoptosis" EXACT [] synonym: "up-regulation of mature B cell apoptosis" EXACT [] synonym: "upregulation of mature B cell apoptosis" EXACT [] xref: GO:0002907 is_a: CCO:P0000614 ! positive regulation of B cell apoptosis is_a: CCO:P0000615 ! regulation of mature B cell apoptosis [Term] id: CCO:P0000618 name: regulation of peripheral B cell deletion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of peripheral B cell deletion." [GOC:add] xref: GO:0002908 is_a: CCO:P0000606 ! regulation of B cell deletion [Term] id: CCO:P0000619 name: negative regulation of peripheral B cell deletion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion." [GOC:add] synonym: "down regulation of peripheral B cell deletion" EXACT [] synonym: "down-regulation of peripheral B cell deletion" EXACT [] synonym: "downregulation of peripheral B cell deletion" EXACT [] synonym: "inhibition of peripheral B cell deletion" NARROW [] xref: GO:0002909 is_a: CCO:P0000607 ! negative regulation of B cell deletion is_a: CCO:P0000618 ! regulation of peripheral B cell deletion [Term] id: CCO:P0000620 name: positive regulation of peripheral B cell deletion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion." [GOC:add] synonym: "activation of peripheral B cell deletion" NARROW [] synonym: "stimulation of peripheral B cell deletion" NARROW [] synonym: "up regulation of peripheral B cell deletion" EXACT [] synonym: "up-regulation of peripheral B cell deletion" EXACT [] synonym: "upregulation of peripheral B cell deletion" EXACT [] xref: GO:0002910 is_a: CCO:P0000608 ! positive regulation of B cell deletion is_a: CCO:P0000618 ! regulation of peripheral B cell deletion [Term] id: CCO:P0000621 name: regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of glycogen anabolism" EXACT [] synonym: "regulation of glycogen biosynthesis" EXACT [] synonym: "regulation of glycogen formation" EXACT [] synonym: "regulation of glycogen synthesis" EXACT [] xref: GO:0005979 is_a: CCO:P0002217 ! regulation of generation of precursor metabolites and energy [Term] id: CCO:P0000622 name: regulation of glycogen catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of glycogen breakdown" EXACT [] synonym: "regulation of glycogen catabolism" EXACT [] synonym: "regulation of glycogen degradation" EXACT [] xref: GO:0005981 is_a: CCO:P0002217 ! regulation of generation of precursor metabolites and energy is_a: CCO:P0002220 ! regulation of cellular carbohydrate catabolic process [Term] id: CCO:P0000623 name: regulation of glycolysis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glycolysis." [GOC:go_curators] subset: gosubset_prok xref: GO:0006110 is_a: CCO:P0002220 ! regulation of cellular carbohydrate catabolic process relationship: has_participant CCO:B0034104 ! K6PL_HUMAN relationship: has_participant CCO:B0034112 ! K6PF_HUMAN relationship: has_participant CCO:B0054803 ! SGT1_HUMAN [Term] id: CCO:P0000624 name: regulation of gluconeogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of glucose biosynthesis" BROAD [] synonym: "regulation of glucose biosynthetic process" BROAD [] xref: GO:0006111 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000625 name: regulation of nucleotide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of nucleotide metabolism" EXACT [] xref: GO:0006140 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0000626 name: regulation of purine base metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of purine base metabolism" EXACT [] xref: GO:0006141 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0000627 name: regulation of pyrimidine base metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidines." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of pyrimidine base metabolism" EXACT [] xref: GO:0006142 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0000628 name: DNA replication namespace: biological_process def: "The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] comment: See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'. subset: goslim_pir subset: gosubset_prok synonym: "DNA biosynthesis" RELATED [] synonym: "DNA biosynthetic process" RELATED [] synonym: "DNA synthesis" RELATED [] xref: GO:0006260 xref: Reactome:176101 xref: Reactome:176116 xref: Reactome:176175 xref: Reactome:176187 xref: Reactome:176250 xref: Reactome:176264 xref: Reactome:176298 xref: Reactome:176318 xref: Reactome:204211 xref: Reactome:205947 xref: Reactome:209363 xref: Reactome:210696 xref: Reactome:210713 xref: Reactome:211049 xref: Reactome:211609 xref: Reactome:213204 xref: Reactome:215512 xref: Reactome:219112 xref: Reactome:220587 xref: Reactome:220604 xref: Reactome:220896 xref: Reactome:221383 xref: Reactome:222984 xref: Reactome:224670 xref: Reactome:227905 xref: Reactome:229236 xref: Reactome:229253 xref: Reactome:229565 xref: Reactome:230019 xref: Reactome:231470 xref: Reactome:236114 xref: Reactome:237238 xref: Reactome:238037 xref: Reactome:239451 xref: Reactome:243273 xref: Reactome:244047 xref: Reactome:244652 xref: Reactome:249742 xref: Reactome:252497 xref: Reactome:255670 xref: Reactome:259062 xref: Reactome:262424 is_a: CCO:P0000887 ! cellular process relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001413 ! RAD1_HUMAN relationship: has_participant CCO:B0001419 ! HUS1_HUMAN relationship: has_participant CCO:B0001426 ! CC45L_HUMAN relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001501 ! K2C7_HUMAN relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0001513 ! PCNA_HUMAN relationship: has_participant CCO:B0001534 ! DNLI1_HUMAN relationship: has_participant CCO:B0001539 ! PTMS_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0001564 ! DPOD1_HUMAN relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0001626 ! NASP_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001638 ! DNLI3_HUMAN relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0001724 ! DPOE1_HUMAN relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0001742 ! CAF1A_HUMAN relationship: has_participant CCO:B0001743 ! CAF1B_HUMAN relationship: has_participant CCO:B0001756 ! ATR_HUMAN relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0001809 ! SPHAR_HUMAN relationship: has_participant CCO:B0001832 ! TBRG1_HUMAN relationship: has_participant CCO:B0001894 ! LIN9_HUMAN relationship: has_participant CCO:B0001902 ! POLS_HUMAN relationship: has_participant CCO:B0001919 ! RAD9B_HUMAN relationship: has_participant CCO:B0001929 ! MCM10_HUMAN relationship: has_participant CCO:B0001975 ! PAPD5_HUMAN relationship: has_participant CCO:B0002009 ! ATRIP_HUMAN relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0002069 ! Q99540_HUMAN relationship: has_participant CCO:B0002077 ! RAD9A_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN relationship: has_participant CCO:B0002142 ! CLSPN_HUMAN relationship: has_participant CCO:B0002194 ! DBF4A_HUMAN relationship: has_participant CCO:B0002210 ! MCM8_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0005388 ! ORC6_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN relationship: has_participant CCO:B0005392 ! ORC3_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005501 ! RFA3_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005507 ! PRI1_HUMAN relationship: has_participant CCO:B0005508 ! PRI2_HUMAN relationship: has_participant CCO:B0005509 ! DPOA2_HUMAN relationship: has_participant CCO:B0005519 ! SET_HUMAN relationship: has_participant CCO:B0005656 ! DTL_HUMAN relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0005809 ! RBBP7_HUMAN relationship: has_participant CCO:B0005882 ! DPOD4_HUMAN relationship: has_participant CCO:B0005883 ! DPOD2_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN relationship: has_participant CCO:B0005885 ! DPOE3_HUMAN relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0005904 ! DPOE2_HUMAN relationship: has_participant CCO:B0006105 ! RFC5_HUMAN relationship: has_participant CCO:B0006114 ! KITH_HUMAN relationship: has_participant CCO:B0006232 ! RIR1_HUMAN relationship: has_participant CCO:B0014914 ! POLH_HUMAN relationship: has_participant CCO:B0015073 ! RBMS1_HUMAN relationship: has_participant CCO:B0017050 ! Q6LES9_HUMAN relationship: has_participant CCO:B0017087 ! Q9Y5S5_HUMAN relationship: has_participant CCO:B0017093 ! Q59EA9_HUMAN relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0017505 ! PSF2_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0019813 ! A6NMQ1_HUMAN relationship: has_participant CCO:B0021696 ! CTGF_HUMAN relationship: has_participant CCO:B0021778 ! RNH2A_HUMAN relationship: has_participant CCO:B0024762 ! POLK_HUMAN relationship: has_participant CCO:B0024942 ! Q6NVK3_HUMAN relationship: has_participant CCO:B0024944 ! Q6ZUA5_HUMAN relationship: has_participant CCO:B0024964 ! Q59FA0_HUMAN relationship: has_participant CCO:B0024966 ! Q308M6_HUMAN relationship: has_participant CCO:B0025407 ! NFIX_HUMAN relationship: has_participant CCO:B0025409 ! Q7Z3K7_HUMAN relationship: has_participant CCO:B0025410 ! Q5W0Y9_HUMAN relationship: has_participant CCO:B0025412 ! NFIC_HUMAN relationship: has_participant CCO:B0025414 ! NFIB_HUMAN relationship: has_participant CCO:B0025416 ! NFIA_HUMAN relationship: has_participant CCO:B0025417 ! Q8TA97_HUMAN relationship: has_participant CCO:B0025419 ! Q6ZNF9_HUMAN relationship: has_participant CCO:B0025421 ! Q5VW27_HUMAN relationship: has_participant CCO:B0025422 ! Q13051_HUMAN relationship: has_participant CCO:B0025423 ! Q5VW31_HUMAN relationship: has_participant CCO:B0025428 ! Q5VW30_HUMAN relationship: has_participant CCO:B0025429 ! Q5VW29_HUMAN relationship: has_participant CCO:B0025430 ! Q5VW26_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: has_participant CCO:B0028704 ! A8MX32_HUMAN relationship: has_participant CCO:B0030757 ! RIR2_HUMAN relationship: has_participant CCO:B0030758 ! RIR2B_HUMAN relationship: has_participant CCO:B0030933 ! DNA2L_HUMAN relationship: has_participant CCO:B0032537 ! SP16H_HUMAN relationship: has_participant CCO:B0034177 ! Q14869_HUMAN relationship: has_participant CCO:B0036627 ! RFC2_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN relationship: has_participant CCO:B0039947 ! STRA8_HUMAN relationship: has_participant CCO:B0039950 ! DCC1_HUMAN relationship: has_participant CCO:B0041262 ! CTF8_HUMAN relationship: has_participant CCO:B0041266 ! CINP_HUMAN relationship: has_participant CCO:B0043835 ! CTF18_HUMAN relationship: has_participant CCO:B0050294 ! HMGB2_HUMAN relationship: has_participant CCO:B0053891 ! A6NL09_HUMAN relationship: has_participant CCO:B0054228 ! B1AKN5_HUMAN relationship: has_participant CCO:B0054229 ! B1AKN6_HUMAN relationship: has_participant CCO:B0054230 ! B1AKN7_HUMAN relationship: has_participant CCO:B0054231 ! B1AKN8_HUMAN relationship: has_participant CCO:B0054290 ! KITM_HUMAN relationship: has_participant CCO:B0054410 ! MYT2_HUMAN relationship: has_participant CCO:B0054547 ! MCM3A_HUMAN relationship: has_participant CCO:B0054574 ! DPOLZ_HUMAN relationship: has_participant CCO:B0054583 ! KIN17_HUMAN relationship: has_participant CCO:B0054732 ! O95165_HUMAN relationship: has_participant CCO:B0054744 ! O95268_HUMAN relationship: has_participant CCO:B0054853 ! IGF1A_HUMAN relationship: has_participant CCO:B0054882 ! TDT_HUMAN relationship: has_participant CCO:B0054893 ! TYSY_HUMAN relationship: has_participant CCO:B0054905 ! DPOLB_HUMAN relationship: has_participant CCO:B0055112 ! TYPH_HUMAN relationship: has_participant CCO:B0055143 ! ACES_HUMAN relationship: has_participant CCO:B0055266 ! DUT_HUMAN relationship: has_participant CCO:B0055321 ! SMBP2_HUMAN relationship: has_participant CCO:B0055505 ! NUP98_HUMAN relationship: has_participant CCO:B0055736 ! SSB_HUMAN relationship: has_participant CCO:B0055880 ! RFA4_HUMAN relationship: has_participant CCO:B0055946 ! TNAP1_HUMAN relationship: has_participant CCO:B0056011 ! PSF1_HUMAN relationship: has_participant CCO:B0056278 ! GRDN_HUMAN relationship: has_participant CCO:B0056354 ! Q53F98_HUMAN relationship: has_participant CCO:B0056457 ! Q5JQP3_HUMAN relationship: has_participant CCO:B0056458 ! Q5JQP8_HUMAN relationship: has_participant CCO:B0056527 ! Q5QJV5_HUMAN relationship: has_participant CCO:B0056891 ! Q6P5X8_HUMAN relationship: has_participant CCO:B0056961 ! Q6VMB5_HUMAN relationship: has_participant CCO:B0057103 ! NOL8_HUMAN relationship: has_participant CCO:B0057185 ! DPOLN_HUMAN relationship: has_participant CCO:B0057279 ! Q86WQ9_HUMAN relationship: has_participant CCO:B0057611 ! HELB_HUMAN relationship: has_participant CCO:B0058049 ! KCD13_HUMAN relationship: has_participant CCO:B0058275 ! CC111_HUMAN relationship: has_participant CCO:B0058337 ! RBM14_HUMAN relationship: has_participant CCO:B0058382 ! PEO1_HUMAN relationship: has_participant CCO:B0058386 ! WRIP1_HUMAN relationship: has_participant CCO:B0058391 ! Q96SE4_HUMAN relationship: has_participant CCO:B0058497 ! SLD5_HUMAN relationship: has_participant CCO:B0058500 ! PSF3_HUMAN relationship: has_participant CCO:B0058515 ! Q9BTN8_HUMAN relationship: has_participant CCO:B0058531 ! REPI1_HUMAN relationship: has_participant CCO:B0058705 ! TXND1_HUMAN relationship: has_participant CCO:B0058749 ! Q9H806_HUMAN relationship: has_participant CCO:B0058762 ! Q9HAJ3_HUMAN relationship: has_participant CCO:B0058787 ! Q9HBN3_HUMAN relationship: has_participant CCO:B0058840 ! DPOLM_HUMAN relationship: has_participant CCO:B0058844 ! NT5M_HUMAN relationship: has_participant CCO:B0058923 ! TREX1_HUMAN relationship: has_participant CCO:B0059092 ! REV1_HUMAN relationship: has_participant CCO:B0059125 ! DPOLL_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN relationship: has_participant CCO:B0059249 ! POLI_HUMAN [Term] id: CCO:P0000629 name: DNA-dependent DNA replication namespace: biological_process def: "The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0006261 xref: GO:0006262 xref: GO:0006263 is_a: CCO:P0000628 ! DNA replication relationship: has_participant CCO:B0001355 ! CDKA1_HUMAN relationship: has_participant CCO:B0001562 ! RFA1_HUMAN relationship: has_participant CCO:B0005500 ! RFA2_HUMAN relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN relationship: has_participant CCO:B0054574 ! DPOLZ_HUMAN relationship: has_participant CCO:B0054905 ! DPOLB_HUMAN relationship: has_participant CCO:B0055678 ! TFAM_HUMAN relationship: has_participant CCO:B0057245 ! RIP_HUMAN relationship: has_participant CCO:B0058402 ! PNKP_HUMAN relationship: has_participant CCO:B0059145 ! DPOG2_HUMAN [Term] id: CCO:P0000630 name: mitochondrial DNA replication namespace: biological_process def: "The process whereby new strands of DNA are synthesized in the mitochondrion." [GOC:ai] synonym: "mitochondrial DNA synthesis" RELATED [] synonym: "mtDNA replication" EXACT [] synonym: "mtDNA synthesis" RELATED [] synonym: "replication of mitochondrial DNA" EXACT [] xref: GO:0006264 is_a: CCO:P0000629 ! DNA-dependent DNA replication relationship: has_participant CCO:B0017165 ! DPOG1_HUMAN [Term] id: CCO:P0000631 name: pre-replicative complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, multiprotein complex that forms at eukaryotic DNA replication origins during late M phase; its presence is required for replication initiation." [GOC:mah] subset: gosubset_prok synonym: "pre-replicative complex formation" EXACT [] xref: GO:0006267 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0000632 name: DNA unwinding during replication namespace: biological_process def: "The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication." [ISBN:071673706X, ISBN:0815316194] subset: gosubset_prok synonym: "DNA unwinding factor" RELATED [] xref: GO:0006268 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001721 ! RAD51_HUMAN relationship: has_participant CCO:B0001753 ! TOP3A_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0001923 ! Q6ZNA8_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN relationship: has_participant CCO:B0005587 ! TOP1_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0024782 ! TOP1M_HUMAN relationship: has_participant CCO:B0050294 ! HMGB2_HUMAN relationship: has_participant CCO:B0054815 ! TOP3B_HUMAN relationship: has_participant CCO:B0055082 ! HMGA1_HUMAN relationship: has_participant CCO:B0055679 ! PURA_HUMAN relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0000633 name: DNA replication, synthesis of RNA primer namespace: biological_process def: "The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis." [PMID:11395402] subset: gosubset_prok synonym: "replication priming" RELATED [] xref: GO:0006269 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005507 ! PRI1_HUMAN relationship: has_participant CCO:B0005508 ! PRI2_HUMAN relationship: has_participant CCO:B0056354 ! Q53F98_HUMAN relationship: has_participant CCO:B0057611 ! HELB_HUMAN relationship: has_participant CCO:B0058275 ! CC111_HUMAN relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0000634 name: DNA replication initiation namespace: biological_process def: "The process by which DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action." [ISBN:071673706X, ISBN:0815316194] subset: gosubset_prok xref: GO:0006270 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001426 ! CC45L_HUMAN relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001628 ! UB2R1_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0005352 ! ORC1_HUMAN relationship: has_participant CCO:B0005353 ! ORC2_HUMAN relationship: has_participant CCO:B0005389 ! ORC4_HUMAN relationship: has_participant CCO:B0005390 ! ORC5_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN relationship: has_participant CCO:B0017892 ! A4D2A2_HUMAN relationship: has_participant CCO:B0025434 ! Q59F49_HUMAN relationship: has_participant CCO:B0048576 ! B1AHB1_HUMAN relationship: has_participant CCO:B0054209 ! B1AHA9_HUMAN relationship: has_participant CCO:B0054410 ! MYT2_HUMAN relationship: has_participant CCO:B0055679 ! PURA_HUMAN relationship: has_participant CCO:B0055880 ! RFA4_HUMAN relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0000635 name: DNA strand elongation during DNA replication namespace: biological_process def: "The process by which a DNA strand is synthesized from template DNA during replication by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand." [ISBN:071673706X, ISBN:0815316194] subset: gosubset_prok synonym: "DNA replication elongation" EXACT [] xref: GO:0006271 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0026184 ! RFC3_HUMAN relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0000636 name: leading strand elongation namespace: biological_process def: "The synthesis of DNA from a template strand in the 5' to 3' direction; leading strand elongation is continuous as it proceeds in the same direction as the replication fork." [ISBN:071673706X, ISBN:0815316194] subset: gosubset_prok xref: GO:0006272 is_a: CCO:P0000635 ! DNA strand elongation during DNA replication relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN [Term] id: CCO:P0000637 name: lagging strand elongation namespace: biological_process def: "The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork." [ISBN:071673706X, ISBN:0815316194] subset: gosubset_prok xref: GO:0006273 is_a: CCO:P0000635 ! DNA strand elongation during DNA replication relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN [Term] id: CCO:P0000638 name: DNA replication termination namespace: biological_process def: "The process by which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet." [GOC:mah, PMID:10209736, PMID:12009298] subset: gosubset_prok xref: GO:0006274 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0000639 name: regulation of DNA replication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA replication." [GOC:go_curators] subset: gosubset_prok xref: GO:0006275 is_a: CCO:P0003015 ! regulation of DNA metabolic process relationship: has_participant CCO:B0001513 ! PCNA_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0001717 ! ID3_HUMAN relationship: has_participant CCO:B0056278 ! GRDN_HUMAN relationship: regulates CCO:P0000628 ! DNA replication [Term] id: CCO:P0000640 name: DNA amplification namespace: biological_process def: "The process by which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment." [ISBN:0721601464] subset: gosubset_prok xref: GO:0006277 is_a: CCO:P0000628 ! DNA replication [Term] id: CCO:P0000641 name: RNA-dependent DNA replication namespace: biological_process def: "The process whereby new strands of DNA are synthesized, using RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0006278 xref: Reactome:162589 xref: Reactome:164516 xref: Reactome:164525 is_a: CCO:P0000628 ! DNA replication relationship: has_participant CCO:B0015556 ! Q86UH8_HUMAN relationship: has_participant CCO:B0053734 ! A2RQR4_HUMAN relationship: has_participant CCO:B0054294 ! O00172_HUMAN relationship: has_participant CCO:B0054312 ! O00360_HUMAN relationship: has_participant CCO:B0054313 ! O00362_HUMAN relationship: has_participant CCO:B0054314 ! O00363_HUMAN relationship: has_participant CCO:B0054315 ! O00366_HUMAN relationship: has_participant CCO:B0054372 ! TERT_HUMAN relationship: has_participant CCO:B0054424 ! O15309_HUMAN relationship: has_participant CCO:B0054425 ! O15310_HUMAN relationship: has_participant CCO:B0054426 ! O15311_HUMAN relationship: has_participant CCO:B0054427 ! O15313_HUMAN relationship: has_participant CCO:B0054786 ! O95724_HUMAN relationship: has_participant CCO:B0054787 ! O95725_HUMAN relationship: has_participant CCO:B0054973 ! POK10_HUMAN relationship: has_participant CCO:B0055625 ! POK4_HUMAN relationship: has_participant CCO:B0055626 ! POK5_HUMAN relationship: has_participant CCO:B0055627 ! POK6_HUMAN relationship: has_participant CCO:B0055628 ! POK9_HUMAN relationship: has_participant CCO:B0055629 ! POK12_HUMAN relationship: has_participant CCO:B0055630 ! POK17_HUMAN relationship: has_participant CCO:B0055665 ! POK11_HUMAN relationship: has_participant CCO:B0055817 ! Q0PKG6_HUMAN relationship: has_participant CCO:B0055823 ! DYH14_HUMAN relationship: has_participant CCO:B0056317 ! Q4JNY2_HUMAN relationship: has_participant CCO:B0056911 ! Q6PID2_HUMAN relationship: has_participant CCO:B0057020 ! Q6ZNE3_HUMAN relationship: has_participant CCO:B0057030 ! Q6ZNU3_HUMAN relationship: has_participant CCO:B0057036 ! Q6ZQX8_HUMAN relationship: has_participant CCO:B0057044 ! Q6ZRZ7_HUMAN relationship: has_participant CCO:B0057047 ! Q6ZS35_HUMAN relationship: has_participant CCO:B0057054 ! Q6ZSG5_HUMAN relationship: has_participant CCO:B0057056 ! Q6ZSN9_HUMAN relationship: has_participant CCO:B0057069 ! Q6ZT97_HUMAN relationship: has_participant CCO:B0057101 ! Q71VD1_HUMAN relationship: has_participant CCO:B0057432 ! Q8N1T7_HUMAN relationship: has_participant CCO:B0057513 ! Q8N886_HUMAN relationship: has_participant CCO:B0057525 ! Q8N8P1_HUMAN relationship: has_participant CCO:B0057530 ! Q8N929_HUMAN relationship: has_participant CCO:B0057607 ! Q8NFP1_HUMAN relationship: has_participant CCO:B0058563 ! POK2_HUMAN relationship: has_participant CCO:B0059064 ! POK7_HUMAN relationship: has_participant CCO:B0059100 ! Q9UDC8_HUMAN relationship: has_participant CCO:B0059101 ! Q9UDC9_HUMAN relationship: has_participant CCO:B0059281 ! POK20_HUMAN relationship: has_participant CCO:B0059287 ! POK3_HUMAN [Term] id: CCO:P0000642 name: premeiotic DNA synthesis namespace: biological_process def: "The replication of DNA that precedes meiotic cell division." [GOC:ai] synonym: "meiotic DNA replication" EXACT [] synonym: "meiotic DNA synthesis" EXACT [] synonym: "premeiotic DNA replication" EXACT [] xref: GO:0006279 is_a: CCO:P0000628 ! DNA replication [Term] id: CCO:P0000643 name: regulation of DNA repair namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA repair." [GOC:go_curators] subset: gosubset_prok xref: GO:0006282 is_a: CCO:P0003015 ! regulation of DNA metabolic process relationship: has_participant CCO:B0001752 ! UB2V1_HUMAN relationship: has_participant CCO:B0001813 ! UB2V2_HUMAN relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN relationship: has_participant CCO:B0014914 ! POLH_HUMAN relationship: has_participant CCO:B0054496 ! O43594_HUMAN [Term] id: CCO:P0000644 name: nucleotide-excision repair, preincision complex stabilization namespace: biological_process def: "The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage." [GOC:elh, PMID:10197977] subset: gosubset_prok xref: GO:0006293 xref: Reactome:109953 is_a: CCO:P0001414 ! positive regulation of protein complex assembly [Term] id: CCO:P0000645 name: mismatch repair namespace: biological_process def: "A system for the correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:11687886] subset: gosubset_prok synonym: "long patch mismatch repair system" NARROW [] synonym: "mismatch repair, MutL-like pathway" RELATED [] synonym: "MMR" EXACT [] synonym: "MutS/MutL/MutH pathway" RELATED [] xref: GO:0006298 xref: GO:0006300 is_a: CCO:P0002259 ! maintenance of fidelity during DNA-dependent DNA replication relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001378 ! MSH4_HUMAN relationship: has_participant CCO:B0001381 ! MSH5_HUMAN relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0001601 ! MLH1_HUMAN relationship: has_participant CCO:B0001620 ! MSH2_HUMAN relationship: has_participant CCO:B0001668 ! PMS1_HUMAN relationship: has_participant CCO:B0001669 ! PMS2_HUMAN relationship: has_participant CCO:B0002200 ! MLH3_HUMAN relationship: has_participant CCO:B0002205 ! MUTYH_HUMAN relationship: has_participant CCO:B0002240 ! EXO1_HUMAN relationship: has_participant CCO:B0005639 ! MSH6_HUMAN relationship: has_participant CCO:B0005720 ! MSH3_HUMAN relationship: has_participant CCO:B0005884 ! DPOD3_HUMAN relationship: has_participant CCO:B0017727 ! A6NMM6_HUMAN relationship: has_participant CCO:B0018492 ! Q9Y6S7_HUMAN relationship: has_participant CCO:B0020445 ! Q5XG96_HUMAN relationship: has_participant CCO:B0020446 ! Q5FBZ4_HUMAN relationship: has_participant CCO:B0020448 ! Q96HL0_HUMAN relationship: has_participant CCO:B0020453 ! Q3BDU4_HUMAN relationship: has_participant CCO:B0023202 ! Q53FK0_HUMAN relationship: has_participant CCO:B0024423 ! Q59EG3_HUMAN relationship: has_participant CCO:B0024426 ! Q53GX1_HUMAN relationship: has_participant CCO:B0024428 ! Q0ZAJ5_HUMAN relationship: has_participant CCO:B0024896 ! A3KGN0_HUMAN relationship: has_participant CCO:B0024897 ! A2ABE9_HUMAN relationship: has_participant CCO:B0024899 ! A3KGM9_HUMAN relationship: has_participant CCO:B0024900 ! A2BEX2_HUMAN relationship: has_participant CCO:B0024901 ! A3KGM6_HUMAN relationship: has_participant CCO:B0024902 ! Q5SSR2_HUMAN relationship: has_participant CCO:B0024905 ! A2BEX3_HUMAN relationship: has_participant CCO:B0024906 ! A2ABF0_HUMAN relationship: has_participant CCO:B0024907 ! A2BEX4_HUMAN relationship: has_participant CCO:B0024909 ! A3KGM5_HUMAN relationship: has_participant CCO:B0024910 ! Q5SSQ8_HUMAN relationship: has_participant CCO:B0024911 ! A2BEX1_HUMAN relationship: has_participant CCO:B0024912 ! A3KGM4_HUMAN relationship: has_participant CCO:B0024914 ! A3KGM7_HUMAN relationship: has_participant CCO:B0025452 ! Q15157_HUMAN relationship: has_participant CCO:B0025454 ! A4D2C1_HUMAN relationship: has_participant CCO:B0025455 ! PMS2L_HUMAN relationship: has_participant CCO:B0025457 ! PMS4L_HUMAN relationship: has_participant CCO:B0025458 ! Q5FBW8_HUMAN relationship: has_participant CCO:B0025459 ! PM2L2_HUMAN relationship: has_participant CCO:B0025462 ! Q16603_HUMAN relationship: has_participant CCO:B0025463 ! PM2L1_HUMAN relationship: has_participant CCO:B0025464 ! PM2L8_HUMAN relationship: has_participant CCO:B0025465 ! Q7Z3Q2_HUMAN relationship: has_participant CCO:B0025467 ! Q6DHX9_HUMAN relationship: has_participant CCO:B0032066 ! A8W2K5_HUMAN relationship: has_participant CCO:B0042401 ! B0V0L9_HUMAN relationship: has_participant CCO:B0042404 ! B0UXD5_HUMAN relationship: has_participant CCO:B0048735 ! PM2L5_HUMAN relationship: has_participant CCO:B0053721 ! A2ABF1_HUMAN relationship: has_participant CCO:B0053743 ! A3KGN1_HUMAN relationship: has_participant CCO:B0053744 ! A3KGN2_HUMAN relationship: has_participant CCO:B0053898 ! A6NLR4_HUMAN relationship: has_participant CCO:B0054147 ! A8W2L5_HUMAN relationship: has_participant CCO:B0054329 ! O00497_HUMAN relationship: has_participant CCO:B0054612 ! ANR17_HUMAN relationship: has_participant CCO:B0054789 ! O95745_HUMAN relationship: has_participant CCO:B0054790 ! PM2LG_HUMAN relationship: has_participant CCO:B0055828 ! Q0ZAJ0_HUMAN relationship: has_participant CCO:B0055829 ! Q0ZAJ1_HUMAN relationship: has_participant CCO:B0055830 ! Q0ZAJ2_HUMAN relationship: has_participant CCO:B0055831 ! Q0ZAJ4_HUMAN relationship: has_participant CCO:B0055832 ! Q0ZAJ7_HUMAN relationship: has_participant CCO:B0055930 ! TDG_HUMAN relationship: has_participant CCO:B0055938 ! PM2LB_HUMAN relationship: has_participant CCO:B0056147 ! Q16544_HUMAN relationship: has_participant CCO:B0056156 ! Q16590_HUMAN relationship: has_participant CCO:B0056174 ! Q16673_HUMAN relationship: has_participant CCO:B0056721 ! Q6DCA4_HUMAN relationship: has_participant CCO:B0056838 ! Q6LAI4_HUMAN relationship: has_participant CCO:B0057217 ! Q7Z7L0_HUMAN relationship: has_participant CCO:B0058923 ! TREX1_HUMAN [Term] id: CCO:P0000646 name: DNA methylation namespace: biological_process def: "The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine." [GOC:ems, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0006306 is_a: CCO:P0002023 ! regulation of gene expression, epigenetic relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005423 ! DNM3B_HUMAN relationship: has_participant CCO:B0005879 ! ATRX_HUMAN relationship: has_participant CCO:B0005907 ! P66A_HUMAN relationship: has_participant CCO:B0006138 ! TRDMT_HUMAN relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0037706 ! DNM3A_HUMAN relationship: has_participant CCO:B0037709 ! Q59HC6_HUMAN relationship: has_participant CCO:B0037714 ! DNM3L_HUMAN relationship: has_participant CCO:B0054194 ! B0YJ06_HUMAN relationship: has_participant CCO:B0054833 ! FOS_HUMAN relationship: has_participant CCO:B0056496 ! Q5JVT4_HUMAN relationship: has_participant CCO:B0056504 ! Q5JY03_HUMAN relationship: has_participant CCO:B0056962 ! MCAF1_HUMAN relationship: has_participant CCO:B0057148 ! Q7Z3E4_HUMAN relationship: has_participant CCO:B0059382 ! HEMK1_HUMAN [Term] id: CCO:P0000647 name: DNA fragmentation during apoptosis namespace: biological_process def: "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." [GOC:mah, ISBN:0721639976] synonym: "DNA catabolic process during apoptosis" EXACT [] synonym: "DNA catabolism during apoptosis" EXACT [] synonym: "DNA fragmentation" BROAD [] xref: GO:0006309 xref: GO:0008178 xref: Reactome:140342 is_a: CCO:P0000674 ! cell structure disassembly during apoptosis relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN relationship: has_participant CCO:B0015270 ! DFFB_HUMAN relationship: has_participant CCO:B0021316 ! Q9C054_HUMAN relationship: has_participant CCO:B0033014 ! SODC_HUMAN relationship: has_participant CCO:B0049794 ! PPT1_HUMAN relationship: has_participant CCO:B0054307 ! DFFA_HUMAN relationship: has_participant CCO:B0054566 ! CIDEA_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN relationship: has_participant CCO:B0055935 ! DNSL3_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058552 ! CECR2_HUMAN relationship: part_of CCO:P0001250 ! apoptotic nuclear changes [Term] id: CCO:P0000648 name: chromatin silencing namespace: biological_process def: "Repression of transcription by conversion of large regions of DNA into an inaccessible state often called heterochromatin." [PMID:10219245] comment: Note that this process is the opposite of chromatin-mediated maintenance of transcription. This regulation is exemplified by members of the Polycomb group, which maintain the inactive state of homeotic gene transcription. synonym: "chromatin-mediated maintenance of transcriptional inactivation" EXACT [] synonym: "chromatin-mediated silencing" EXACT [] synonym: "heterochromatic silencing" EXACT [] synonym: "TGS" EXACT [] synonym: "transcriptional gene silencing" EXACT [] xref: GO:0006342 xref: GO:0016440 is_a: CCO:P0001125 ! gene silencing is_a: CCO:P0002562 ! negative regulation of gene expression, epigenetic is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002244 ! HDAC5_HUMAN relationship: has_participant CCO:B0017935 ! A7VJH3_HUMAN relationship: has_participant CCO:B0036287 ! HILS1_HUMAN relationship: has_participant CCO:B0054178 ! B0QZ35_HUMAN relationship: has_participant CCO:B0054943 ! STP1_HUMAN relationship: has_participant CCO:B0056995 ! Q6ZMU6_HUMAN relationship: has_participant CCO:B0056999 ! Q6ZMZ2_HUMAN relationship: has_participant CCO:B0057009 ! Q6ZN34_HUMAN relationship: has_participant CCO:B0057492 ! SIRT6_HUMAN relationship: has_participant CCO:B0057562 ! Q8NC36_HUMAN relationship: has_participant CCO:B0058204 ! SIRT1_HUMAN relationship: has_participant CCO:B0058895 ! SIRT7_HUMAN relationship: has_participant CCO:B0058924 ! SIRT3_HUMAN relationship: has_participant CCO:B0058951 ! SIRT5_HUMAN relationship: has_participant CCO:B0059404 ! SIRT4_HUMAN [Term] id: CCO:P0000649 name: establishment of chromatin silencing namespace: biological_process def: "The initial formation of transcriptionally silent heterochromatin." [GOC:mah] synonym: "establishment of heterochromatic silencing" EXACT [] xref: GO:0006343 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000648 ! chromatin silencing [Term] id: CCO:P0000650 name: maintenance of chromatin silencing namespace: biological_process def: "The maintenance of chromatin in a transciptionally silent heterochromatin state." [GOC:mah] synonym: "maintenance of heterochromatic silencing" EXACT [] xref: GO:0006344 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000648 ! chromatin silencing [Term] id: CCO:P0000651 name: loss of chromatin silencing namespace: biological_process def: "The process leading to expression of genes that are typically not expressed due to silencing by regulatory proteins." [GOC:go_curators] xref: GO:0006345 is_a: CCO:P0002563 ! positive regulation of gene expression, epigenetic is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: has_participant CCO:B0005268 ! ASF1A_HUMAN relationship: has_participant CCO:B0055082 ! HMGA1_HUMAN [Term] id: CCO:P0000652 name: methylation-dependent chromatin silencing namespace: biological_process def: "Repression of transcription by methylation of DNA, leading to the formation of heterochromatin." [GOC:mah] synonym: "methylation-dependent heterochromatic silencing" EXACT [] xref: GO:0006346 is_a: CCO:P0000648 ! chromatin silencing relationship: has_participant CCO:B0002161 ! HELLS_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN [Term] id: CCO:P0000653 name: chromatin silencing at telomere namespace: biological_process def: "Repression of transcription of telomeric DNA by the formation of heterochromatin." [PMID:10219245] synonym: "heterochromatic silencing at telomere" EXACT [] xref: GO:0006348 is_a: CCO:P0000648 ! chromatin silencing relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN [Term] id: CCO:P0000654 name: genetic imprinting namespace: biological_process def: "Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself." [GOC:ems, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:11498578] synonym: "DNA imprinting" EXACT [] xref: GO:0006349 is_a: CCO:P0002023 ! regulation of gene expression, epigenetic relationship: has_participant CCO:B0001453 ! DIRA3_HUMAN relationship: has_participant CCO:B0001472 ! IGF2_HUMAN relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0037714 ! DNM3L_HUMAN [Term] id: CCO:P0000655 name: regulation of transcription, DNA-dependent namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA-dependent transcription." [GOC:go_curators] subset: gosubset_prok synonym: "transcriptional control" BROAD [] xref: GO:0006355 is_a: CCO:P0002369 ! regulation of transcription is_a: CCO:P0003068 ! regulation of RNA metabolic process relationship: has_participant CCO:B0001317 ! E2F8_HUMAN relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0001347 ! FOXN3_HUMAN relationship: has_participant CCO:B0001352 ! E2F3_HUMAN relationship: has_participant CCO:B0001357 ! ANM5_HUMAN relationship: has_participant CCO:B0001358 ! OVOL1_HUMAN relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001376 ! HDAC3_HUMAN relationship: has_participant CCO:B0001391 ! SUV91_HUMAN relationship: has_participant CCO:B0001407 ! HBP1_HUMAN relationship: has_participant CCO:B0001410 ! CCNT1_HUMAN relationship: has_participant CCO:B0001412 ! CCNT2_HUMAN relationship: has_participant CCO:B0001428 ! ERN1_HUMAN relationship: has_participant CCO:B0001429 ! E2F6_HUMAN relationship: has_participant CCO:B0001431 ! SUPT3_HUMAN relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0001445 ! HEXI1_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001487 ! JUN_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001505 ! MYBB_HUMAN relationship: has_participant CCO:B0001510 ! IRF1_HUMAN relationship: has_participant CCO:B0001522 ! FOSL1_HUMAN relationship: has_participant CCO:B0001530 ! JUNB_HUMAN relationship: has_participant CCO:B0001536 ! WT1_HUMAN relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0001543 ! TAF1_HUMAN relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0001553 ! CCNC_HUMAN relationship: has_participant CCO:B0001558 ! MCM3_HUMAN relationship: has_participant CCO:B0001563 ! CALR_HUMAN relationship: has_participant CCO:B0001567 ! RBL1_HUMAN relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0001585 ! TF2H1_HUMAN relationship: has_participant CCO:B0001588 ! MCM5_HUMAN relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001627 ! CDK8_HUMAN relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0001631 ! MCM2_HUMAN relationship: has_participant CCO:B0001642 ! ERF_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001647 ! CDK9_HUMAN relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001652 ! CCNH_HUMAN relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0001664 ! FOSB_HUMAN relationship: has_participant CCO:B0001668 ! PMS1_HUMAN relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0001706 ! FOXO4_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0001725 ! RBL2_HUMAN relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0001741 ! ZBT17_HUMAN relationship: has_participant CCO:B0001742 ! CAF1A_HUMAN relationship: has_participant CCO:B0001743 ! CAF1B_HUMAN relationship: has_participant CCO:B0001752 ! UB2V1_HUMAN relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0001770 ! NFYC_HUMAN relationship: has_participant CCO:B0001776 ! TFDP1_HUMAN relationship: has_participant CCO:B0001777 ! TFDP2_HUMAN relationship: has_participant CCO:B0001781 ! E2F2_HUMAN relationship: has_participant CCO:B0001783 ! HIC1_HUMAN relationship: has_participant CCO:B0001785 ! MCM6_HUMAN relationship: has_participant CCO:B0001804 ! E2F5_HUMAN relationship: has_participant CCO:B0001817 ! E2F4_HUMAN relationship: has_participant CCO:B0001831 ! Q3LRW5_HUMAN relationship: has_participant CCO:B0001833 ! Q499G5_HUMAN relationship: has_participant CCO:B0001849 ! TFDP3_HUMAN relationship: has_participant CCO:B0001854 ! Q5JSB5_HUMAN relationship: has_participant CCO:B0001855 ! Q5JSB6_HUMAN relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0001917 ! Q6Q9Z6_HUMAN relationship: has_participant CCO:B0001928 ! ERN2_HUMAN relationship: has_participant CCO:B0001938 ! PB1_HUMAN relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0001959 ! TAF1L_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0001971 ! BANP_HUMAN relationship: has_participant CCO:B0001976 ! RCBT1_HUMAN relationship: has_participant CCO:B0001995 ! RBCC1_HUMAN relationship: has_participant CCO:B0002002 ! HDAC7_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0002022 ! NGN1_HUMAN relationship: has_participant CCO:B0002031 ! E2F7_HUMAN relationship: has_participant CCO:B0002049 ! HEXI2_HUMAN relationship: has_participant CCO:B0002063 ! UHRF1_HUMAN relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0002074 ! MNT_HUMAN relationship: has_participant CCO:B0002075 ! NECD_HUMAN relationship: has_participant CCO:B0002083 ! GFI1_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0002111 ! PCGF6_HUMAN relationship: has_participant CCO:B0002128 ! TSYL2_HUMAN relationship: has_participant CCO:B0002130 ! HIPK2_HUMAN relationship: has_participant CCO:B0002131 ! PININ_HUMAN relationship: has_participant CCO:B0002133 ! TXNIP_HUMAN relationship: has_participant CCO:B0002139 ! SUV92_HUMAN relationship: has_participant CCO:B0002146 ! TF7L1_HUMAN relationship: has_participant CCO:B0002148 ! CHM1A_HUMAN relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0002161 ! HELLS_HUMAN relationship: has_participant CCO:B0002184 ! HM20B_HUMAN relationship: has_participant CCO:B0002192 ! HDAC6_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0002202 ! SRTD1_HUMAN relationship: has_participant CCO:B0002210 ! MCM8_HUMAN relationship: has_participant CCO:B0002218 ! CCNL1_HUMAN relationship: has_participant CCO:B0002222 ! HDAC9_HUMAN relationship: has_participant CCO:B0002231 ! PLAL1_HUMAN relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0002235 ! TIM_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0002241 ! CD2L2_HUMAN relationship: has_participant CCO:B0002244 ! HDAC5_HUMAN relationship: has_participant CCO:B0002248 ! LZTS1_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0002263 ! EID1_HUMAN relationship: has_participant CCO:B0005176 ! T22D4_HUMAN relationship: has_participant CCO:B0005191 ! SATB1_HUMAN relationship: has_participant CCO:B0005195 ! DACH1_HUMAN relationship: has_participant CCO:B0005209 ! GABP2_HUMAN relationship: has_participant CCO:B0005213 ! IKZF1_HUMAN relationship: has_participant CCO:B0005214 ! ZN581_HUMAN relationship: has_participant CCO:B0005218 ! ZMIZ2_HUMAN relationship: has_participant CCO:B0005225 ! EWS_HUMAN relationship: has_participant CCO:B0005228 ! ZN580_HUMAN relationship: has_participant CCO:B0005234 ! NONO_HUMAN relationship: has_participant CCO:B0005263 ! ZN567_HUMAN relationship: has_participant CCO:B0005268 ! ASF1A_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0005275 ! KHDR3_HUMAN relationship: has_participant CCO:B0005276 ! ZN764_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005296 ! HM20A_HUMAN relationship: has_participant CCO:B0005297 ! ZN263_HUMAN relationship: has_participant CCO:B0005301 ! MAF1_HUMAN relationship: has_participant CCO:B0005308 ! ZN451_HUMAN relationship: has_participant CCO:B0005320 ! BATF_HUMAN relationship: has_participant CCO:B0005321 ! PIAS2_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN relationship: has_participant CCO:B0005336 ! MAX_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005340 ! PAX5_HUMAN relationship: has_participant CCO:B0005341 ! HDA10_HUMAN relationship: has_participant CCO:B0005343 ! HDAC2_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005354 ! T2FA_HUMAN relationship: has_participant CCO:B0005355 ! CAND1_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005363 ! EAF1_HUMAN relationship: has_participant CCO:B0005364 ! RUVB2_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005368 ! ING3_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005370 ! MO4L2_HUMAN relationship: has_participant CCO:B0005371 ! EPC2_HUMAN relationship: has_participant CCO:B0005377 ! AP2C_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005382 ! NFYB_HUMAN relationship: has_participant CCO:B0005384 ! NFYA_HUMAN relationship: has_participant CCO:B0005391 ! MCM4_HUMAN relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005396 ! TCRG1_HUMAN relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005399 ! MYST2_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005404 ! SETB1_HUMAN relationship: has_participant CCO:B0005412 ! TP53B_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005419 ! SMRD2_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005444 ! CHD8_HUMAN relationship: has_participant CCO:B0005451 ! HXC10_HUMAN relationship: has_participant CCO:B0005468 ! MED28_HUMAN relationship: has_participant CCO:B0005475 ! MED9_HUMAN relationship: has_participant CCO:B0005477 ! TRIB3_HUMAN relationship: has_participant CCO:B0005481 ! TBP_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005485 ! SP1_HUMAN relationship: has_participant CCO:B0005486 ! HRX_HUMAN relationship: has_participant CCO:B0005497 ! ARID2_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005552 ! NCOA7_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0005573 ! MED10_HUMAN relationship: has_participant CCO:B0005574 ! MED29_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005578 ! ZN655_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0005589 ! LSD1_HUMAN relationship: has_participant CCO:B0005601 ! MYT1L_HUMAN relationship: has_participant CCO:B0005607 ! MYT1_HUMAN relationship: has_participant CCO:B0005613 ! SET1A_HUMAN relationship: has_participant CCO:B0005614 ! ASH2L_HUMAN relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0005623 ! MEOX2_HUMAN relationship: has_participant CCO:B0005629 ! KS6A4_HUMAN relationship: has_participant CCO:B0005632 ! MYB_HUMAN relationship: has_participant CCO:B0005637 ! ELK1_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005668 ! ELOB_HUMAN relationship: has_participant CCO:B0005675 ! HIPK1_HUMAN relationship: has_participant CCO:B0005680 ! AP2B_HUMAN relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0005686 ! HNRPD_HUMAN relationship: has_participant CCO:B0005690 ! TLE3_HUMAN relationship: has_participant CCO:B0005693 ! ARI4A_HUMAN relationship: has_participant CCO:B0005694 ! SDS3_HUMAN relationship: has_participant CCO:B0005701 ! HDA11_HUMAN relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0005742 ! YBOX1_HUMAN relationship: has_participant CCO:B0005755 ! LPPRC_HUMAN relationship: has_participant CCO:B0005769 ! SSRP1_HUMAN relationship: has_participant CCO:B0005779 ! ENOA_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005787 ! MED18_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005790 ! MED15_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005795 ! MED22_HUMAN relationship: has_participant CCO:B0005796 ! MED11_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005798 ! MED8_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005801 ! MD13L_HUMAN relationship: has_participant CCO:B0005807 ! SIN3B_HUMAN relationship: has_participant CCO:B0005809 ! RBBP7_HUMAN relationship: has_participant CCO:B0005830 ! FHL2_HUMAN relationship: has_participant CCO:B0005839 ! CTND1_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0005878 ! GABPA_HUMAN relationship: has_participant CCO:B0005879 ! ATRX_HUMAN relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0005895 ! PBX2_HUMAN relationship: has_participant CCO:B0005907 ! P66A_HUMAN relationship: has_participant CCO:B0005908 ! P66B_HUMAN relationship: has_participant CCO:B0005917 ! MO4L1_HUMAN relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0005937 ! TAF10_HUMAN relationship: has_participant CCO:B0005938 ! TAF9_HUMAN relationship: has_participant CCO:B0005942 ! WASL_HUMAN relationship: has_participant CCO:B0005945 ! ATX7_HUMAN relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0005981 ! TRI27_HUMAN relationship: has_participant CCO:B0005984 ! TMF1_HUMAN relationship: has_participant CCO:B0005987 ! AES_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0006011 ! TYY1_HUMAN relationship: has_participant CCO:B0006014 ! ZN443_HUMAN relationship: has_participant CCO:B0006016 ! ATF7_HUMAN relationship: has_participant CCO:B0006020 ! BC11A_HUMAN relationship: has_participant CCO:B0006027 ! ELF1_HUMAN relationship: has_participant CCO:B0006030 ! COE1_HUMAN relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0006033 ! ARNT2_HUMAN relationship: has_participant CCO:B0006035 ! PR285_HUMAN relationship: has_participant CCO:B0006038 ! NKRF_HUMAN relationship: has_participant CCO:B0006041 ! TBL1R_HUMAN relationship: has_participant CCO:B0006042 ! MINT_HUMAN relationship: has_participant CCO:B0006048 ! HSF4_HUMAN relationship: has_participant CCO:B0006049 ! PO2F3_HUMAN relationship: has_participant CCO:B0006051 ! JHD1A_HUMAN relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0006069 ! PO2F1_HUMAN relationship: has_participant CCO:B0006070 ! EGR2_HUMAN relationship: has_participant CCO:B0006073 ! AN32A_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN relationship: has_participant CCO:B0006077 ! EPAS1_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0006086 ! ASCC2_HUMAN relationship: has_participant CCO:B0006113 ! SAP18_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN relationship: has_participant CCO:B0006161 ! SFPQ_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0006206 ! AF9_HUMAN relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN relationship: has_participant CCO:B0006218 ! PQBP1_HUMAN relationship: has_participant CCO:B0006243 ! RFX1_HUMAN relationship: has_participant CCO:B0006246 ! TGIF1_HUMAN relationship: has_participant CCO:B0006254 ! ZNF7_HUMAN relationship: has_participant CCO:B0006294 ! PTOV1_HUMAN relationship: has_participant CCO:B0006301 ! ST65G_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN relationship: has_participant CCO:B0006341 ! PO3F3_HUMAN relationship: has_participant CCO:B0014838 ! SPT6H_HUMAN relationship: has_participant CCO:B0014847 ! SETD2_HUMAN relationship: has_participant CCO:B0014928 ! TAF9B_HUMAN relationship: has_participant CCO:B0015066 ! FOXN2_HUMAN relationship: has_participant CCO:B0015067 ! Q6P4Q2_HUMAN relationship: has_participant CCO:B0015238 ! FOXK2_HUMAN relationship: has_participant CCO:B0015239 ! FOXK1_HUMAN relationship: has_participant CCO:B0015243 ! TCEA3_HUMAN relationship: has_participant CCO:B0015398 ! MXI1_HUMAN relationship: has_participant CCO:B0015399 ! MAD4_HUMAN relationship: has_participant CCO:B0015400 ! MAD1_HUMAN relationship: has_participant CCO:B0015493 ! SUV42_HUMAN relationship: has_participant CCO:B0015494 ! SUV41_HUMAN relationship: has_participant CCO:B0015655 ! HIPK3_HUMAN relationship: has_participant CCO:B0015701 ! Q8N6B5_HUMAN relationship: has_participant CCO:B0015705 ! Q8NAN6_HUMAN relationship: has_participant CCO:B0015706 ! Q0PRL4_HUMAN relationship: has_participant CCO:B0015709 ! Q8N2P0_HUMAN relationship: has_participant CCO:B0015710 ! Q7Z7F8_HUMAN relationship: has_participant CCO:B0015712 ! FOXP1_HUMAN relationship: has_participant CCO:B0015713 ! FOXP4_HUMAN relationship: has_participant CCO:B0015715 ! Q96AP5_HUMAN relationship: has_participant CCO:B0015717 ! FOXP2_HUMAN relationship: has_participant CCO:B0015718 ! Q68DX8_HUMAN relationship: has_participant CCO:B0015719 ! Q8IW55_HUMAN relationship: has_participant CCO:B0015721 ! A3KMG1_HUMAN relationship: has_participant CCO:B0015979 ! MNDA_HUMAN relationship: has_participant CCO:B0016000 ! MTERF_HUMAN relationship: has_participant CCO:B0016003 ! MTER3_HUMAN relationship: has_participant CCO:B0016028 ! HIRA_HUMAN relationship: has_participant CCO:B0016195 ! KHDR2_HUMAN relationship: has_participant CCO:B0016694 ! FOXI1_HUMAN relationship: has_participant CCO:B0016695 ! FOXE1_HUMAN relationship: has_participant CCO:B0016696 ! FOXD2_HUMAN relationship: has_participant CCO:B0016698 ! FX4L4_HUMAN relationship: has_participant CCO:B0016699 ! FOXF1_HUMAN relationship: has_participant CCO:B0016702 ! Q4JHB7_HUMAN relationship: has_participant CCO:B0016703 ! Q6VB86_HUMAN relationship: has_participant CCO:B0016706 ! FOXD1_HUMAN relationship: has_participant CCO:B0016708 ! FX4L1_HUMAN relationship: has_participant CCO:B0016714 ! FOXB2_HUMAN relationship: has_participant CCO:B0016715 ! FOXQ1_HUMAN relationship: has_participant CCO:B0016719 ! FOXF2_HUMAN relationship: has_participant CCO:B0016720 ! FX4L5_HUMAN relationship: has_participant CCO:B0016722 ! FOXL1_HUMAN relationship: has_participant CCO:B0016723 ! Q8WXT4_HUMAN relationship: has_participant CCO:B0016724 ! FX4L6_HUMAN relationship: has_participant CCO:B0016726 ! Q14CL2_HUMAN relationship: has_participant CCO:B0016727 ! FOXE3_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0016733 ! FOXD3_HUMAN relationship: has_participant CCO:B0016737 ! FX4L3_HUMAN relationship: has_participant CCO:B0016740 ! FOXG1_HUMAN relationship: has_participant CCO:B0016741 ! Q5T109_HUMAN relationship: has_participant CCO:B0016794 ! PLAG1_HUMAN relationship: has_participant CCO:B0016798 ! PLAL2_HUMAN relationship: has_participant CCO:B0016881 ! FOXO1_HUMAN relationship: has_participant CCO:B0016924 ! TLE4_HUMAN relationship: has_participant CCO:B0017097 ! Z816A_HUMAN relationship: has_participant CCO:B0017101 ! ZN528_HUMAN relationship: has_participant CCO:B0017103 ! ZNF83_HUMAN relationship: has_participant CCO:B0017118 ! ING2_HUMAN relationship: has_participant CCO:B0017601 ! ZNFX1_HUMAN relationship: has_participant CCO:B0017820 ! NOTC3_HUMAN relationship: has_participant CCO:B0017875 ! ZFP62_HUMAN relationship: has_participant CCO:B0017876 ! Q6ZN27_HUMAN relationship: has_participant CCO:B0017883 ! ZN616_HUMAN relationship: has_participant CCO:B0017884 ! ZN546_HUMAN relationship: has_participant CCO:B0017927 ! MYST3_HUMAN relationship: has_participant CCO:B0017931 ! MYST4_HUMAN relationship: has_participant CCO:B0017935 ! A7VJH3_HUMAN relationship: has_participant CCO:B0017945 ! PURB_HUMAN relationship: has_participant CCO:B0017947 ! PHF5A_HUMAN relationship: has_participant CCO:B0018285 ! TF2H2_HUMAN relationship: has_participant CCO:B0018367 ! ATF2_HUMAN relationship: has_participant CCO:B0018381 ! A1L3Z2_HUMAN relationship: has_participant CCO:B0018382 ! CREB5_HUMAN relationship: has_participant CCO:B0018461 ! PIAS3_HUMAN relationship: has_participant CCO:B0018465 ! ZN326_HUMAN relationship: has_participant CCO:B0018552 ! Q4VXV6_HUMAN relationship: has_participant CCO:B0018555 ! Q4VXV5_HUMAN relationship: has_participant CCO:B0018582 ! TAF12_HUMAN relationship: has_participant CCO:B0018662 ! Q8IW86_HUMAN relationship: has_participant CCO:B0018664 ! TBX22_HUMAN relationship: has_participant CCO:B0018665 ! Q9HA44_HUMAN relationship: has_participant CCO:B0018667 ! Q5JT54_HUMAN relationship: has_participant CCO:B0018668 ! TBX1_HUMAN relationship: has_participant CCO:B0018669 ! TBX15_HUMAN relationship: has_participant CCO:B0018670 ! TBX6_HUMAN relationship: has_participant CCO:B0018671 ! Q5JZ06_HUMAN relationship: has_participant CCO:B0018672 ! Q000T4_HUMAN relationship: has_participant CCO:B0018676 ! TBX10_HUMAN relationship: has_participant CCO:B0018677 ! TBX18_HUMAN relationship: has_participant CCO:B0018678 ! TBX20_HUMAN relationship: has_participant CCO:B0018951 ! ATF6A_HUMAN relationship: has_participant CCO:B0018982 ! SNF8_HUMAN relationship: has_participant CCO:B0019065 ! Q495X4_HUMAN relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0019068 ! RORB_HUMAN relationship: has_participant CCO:B0019074 ! CNOT6_HUMAN relationship: has_participant CCO:B0019239 ! Q5FBX3_HUMAN relationship: has_participant CCO:B0019363 ! TAF5L_HUMAN relationship: has_participant CCO:B0019365 ! TAF5_HUMAN relationship: has_participant CCO:B0019407 ! Q6W9G7_HUMAN relationship: has_participant CCO:B0019411 ! Q6P1W9_HUMAN relationship: has_participant CCO:B0019498 ! SCND1_HUMAN relationship: has_participant CCO:B0019767 ! WDHD1_HUMAN relationship: has_participant CCO:B0020218 ! CSEN_HUMAN relationship: has_participant CCO:B0020253 ! SOX12_HUMAN relationship: has_participant CCO:B0020254 ! SOX11_HUMAN relationship: has_participant CCO:B0020256 ! SOX1_HUMAN relationship: has_participant CCO:B0020258 ! O95131_HUMAN relationship: has_participant CCO:B0020259 ! SOX18_HUMAN relationship: has_participant CCO:B0020263 ! SOX21_HUMAN relationship: has_participant CCO:B0020265 ! Q5W0Q1_HUMAN relationship: has_participant CCO:B0020266 ! SOX30_HUMAN relationship: has_participant CCO:B0020267 ! SOX14_HUMAN relationship: has_participant CCO:B0020275 ! SOX3_HUMAN relationship: has_participant CCO:B0020282 ! SRY_HUMAN relationship: has_participant CCO:B0020283 ! SOX15_HUMAN relationship: has_participant CCO:B0020286 ! O95130_HUMAN relationship: has_participant CCO:B0020290 ! Q7Z5C6_HUMAN relationship: has_participant CCO:B0020291 ! O95132_HUMAN relationship: has_participant CCO:B0020292 ! SOX4_HUMAN relationship: has_participant CCO:B0020295 ! SOX2_HUMAN relationship: has_participant CCO:B0020296 ! Q52MY2_HUMAN relationship: has_participant CCO:B0020321 ! MIER1_HUMAN relationship: has_participant CCO:B0020453 ! Q3BDU4_HUMAN relationship: has_participant CCO:B0020552 ! RING2_HUMAN relationship: has_participant CCO:B0020553 ! RING1_HUMAN relationship: has_participant CCO:B0020930 ! GLIS2_HUMAN relationship: has_participant CCO:B0020932 ! GLIS1_HUMAN relationship: has_participant CCO:B0020975 ! T2FB_HUMAN relationship: has_participant CCO:B0020998 ! HELC1_HUMAN relationship: has_participant CCO:B0021154 ! Q6PIQ2_HUMAN relationship: has_participant CCO:B0021155 ! Q86VG0_HUMAN relationship: has_participant CCO:B0021156 ! SCND2_HUMAN relationship: has_participant CCO:B0021159 ! Q86V93_HUMAN relationship: has_participant CCO:B0021160 ! Q07644_HUMAN relationship: has_participant CCO:B0021241 ! TF2LX_HUMAN relationship: has_participant CCO:B0021248 ! Q3ZCM9_HUMAN relationship: has_participant CCO:B0021260 ! TF2LY_HUMAN relationship: has_participant CCO:B0021266 ! TGIF2_HUMAN relationship: has_participant CCO:B0021340 ! CHSP1_HUMAN relationship: has_participant CCO:B0021341 ! CSDC2_HUMAN relationship: has_participant CCO:B0021435 ! ATF4_HUMAN relationship: has_participant CCO:B0021690 ! RPB1_HUMAN relationship: has_participant CCO:B0021707 ! CITE4_HUMAN relationship: has_participant CCO:B0021755 ! A0N2G3_HUMAN relationship: has_participant CCO:B0021859 ! IKZF2_HUMAN relationship: has_participant CCO:B0021866 ! IKZF4_HUMAN relationship: has_participant CCO:B0022038 ! ZHX2_HUMAN relationship: has_participant CCO:B0022040 ! ZHX3_HUMAN relationship: has_participant CCO:B0022042 ! Q6NUJ7_HUMAN relationship: has_participant CCO:B0022045 ! Q5JZ70_HUMAN relationship: has_participant CCO:B0022046 ! Q5JZ69_HUMAN relationship: has_participant CCO:B0022296 ! Q3LRW1_HUMAN relationship: has_participant CCO:B0022298 ! Q3LRW4_HUMAN relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0022308 ! Q1MSW9_HUMAN relationship: has_participant CCO:B0022312 ! Q3LRW3_HUMAN relationship: has_participant CCO:B0022381 ! ZN667_HUMAN relationship: has_participant CCO:B0022382 ! Q9ULA1_HUMAN relationship: has_participant CCO:B0022444 ! TF2B_HUMAN relationship: has_participant CCO:B0022449 ! A2I2N5_HUMAN relationship: has_participant CCO:B0022450 ! Q5H8X5_HUMAN relationship: has_participant CCO:B0022451 ! Q8TAR6_HUMAN relationship: has_participant CCO:B0022452 ! PER3_HUMAN relationship: has_participant CCO:B0022490 ! MAGG1_HUMAN relationship: has_participant CCO:B0022617 ! A6ZIS4_HUMAN relationship: has_participant CCO:B0022629 ! A6ZIT3_HUMAN relationship: has_participant CCO:B0023365 ! PPRC1_HUMAN relationship: has_participant CCO:B0023371 ! HIC2_HUMAN relationship: has_participant CCO:B0023418 ! STAT4_HUMAN relationship: has_participant CCO:B0023422 ! STAT2_HUMAN relationship: has_participant CCO:B0023430 ! Q67C41_HUMAN relationship: has_participant CCO:B0023501 ! TAF6L_HUMAN relationship: has_participant CCO:B0023930 ! BRM1L_HUMAN relationship: has_participant CCO:B0023940 ! CCNL2_HUMAN relationship: has_participant CCO:B0023973 ! TF2H3_HUMAN relationship: has_participant CCO:B0024344 ! Q9UG28_HUMAN relationship: has_participant CCO:B0024472 ! BNC1_HUMAN relationship: has_participant CCO:B0024477 ! BNC2_HUMAN relationship: has_participant CCO:B0024549 ! Q4LE28_HUMAN relationship: has_participant CCO:B0024552 ! O60424_HUMAN relationship: has_participant CCO:B0024794 ! ZIC3_HUMAN relationship: has_participant CCO:B0024821 ! CEBPZ_HUMAN relationship: has_participant CCO:B0024842 ! RARB_HUMAN relationship: has_participant CCO:B0024846 ! Q3SB16_HUMAN relationship: has_participant CCO:B0024847 ! Q15156_HUMAN relationship: has_participant CCO:B0024850 ! Q658K5_HUMAN relationship: has_participant CCO:B0024853 ! RARA_HUMAN relationship: has_participant CCO:B0024873 ! NR6A1_HUMAN relationship: has_participant CCO:B0024874 ! COT1_HUMAN relationship: has_participant CCO:B0024875 ! COT2_HUMAN relationship: has_participant CCO:B0024877 ! Q7Z5U9_HUMAN relationship: has_participant CCO:B0024878 ! RXRB_HUMAN relationship: has_participant CCO:B0024881 ! RXRG_HUMAN relationship: has_participant CCO:B0024884 ! Q5STQ1_HUMAN relationship: has_participant CCO:B0024886 ! RXRA_HUMAN relationship: has_participant CCO:B0024889 ! Q3KQR7_HUMAN relationship: has_participant CCO:B0024893 ! NR2F6_HUMAN relationship: has_participant CCO:B0025086 ! Q6Q9Z7_HUMAN relationship: has_participant CCO:B0025365 ! OVOL2_HUMAN relationship: has_participant CCO:B0025407 ! NFIX_HUMAN relationship: has_participant CCO:B0025409 ! Q7Z3K7_HUMAN relationship: has_participant CCO:B0025410 ! Q5W0Y9_HUMAN relationship: has_participant CCO:B0025412 ! NFIC_HUMAN relationship: has_participant CCO:B0025414 ! NFIB_HUMAN relationship: has_participant CCO:B0025416 ! NFIA_HUMAN relationship: has_participant CCO:B0025417 ! Q8TA97_HUMAN relationship: has_participant CCO:B0025419 ! Q6ZNF9_HUMAN relationship: has_participant CCO:B0025421 ! Q5VW27_HUMAN relationship: has_participant CCO:B0025422 ! Q13051_HUMAN relationship: has_participant CCO:B0025423 ! Q5VW31_HUMAN relationship: has_participant CCO:B0025428 ! Q5VW30_HUMAN relationship: has_participant CCO:B0025429 ! Q5VW29_HUMAN relationship: has_participant CCO:B0025430 ! Q5VW26_HUMAN relationship: has_participant CCO:B0025485 ! Q2A130_HUMAN relationship: has_participant CCO:B0026248 ! ERCC2_HUMAN relationship: has_participant CCO:B0026249 ! ZMY11_HUMAN relationship: has_participant CCO:B0026258 ! TCF19_HUMAN relationship: has_participant CCO:B0026467 ! HSF1_HUMAN relationship: has_participant CCO:B0026475 ! Q6ZTI4_HUMAN relationship: has_participant CCO:B0026476 ! A8MW26_HUMAN relationship: has_participant CCO:B0026489 ! HSF2_HUMAN relationship: has_participant CCO:B0026530 ! NPAS2_HUMAN relationship: has_participant CCO:B0026531 ! CLOCK_HUMAN relationship: has_participant CCO:B0026532 ! Q53EU0_HUMAN relationship: has_participant CCO:B0026534 ! A6NP27_HUMAN relationship: has_participant CCO:B0026837 ! A8MRA5_HUMAN relationship: has_participant CCO:B0026855 ! ARI4B_HUMAN relationship: has_participant CCO:B0026862 ! A8K7L7_HUMAN relationship: has_participant CCO:B0026863 ! A8MUP8_HUMAN relationship: has_participant CCO:B0027079 ! GT2D1_HUMAN relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN relationship: has_participant CCO:B0028073 ! RFX3_HUMAN relationship: has_participant CCO:B0028074 ! RFX2_HUMAN relationship: has_participant CCO:B0028081 ! A8K581_HUMAN relationship: has_participant CCO:B0028183 ! A8K5Y0_HUMAN relationship: has_participant CCO:B0028295 ! A8MSJ8_HUMAN relationship: has_participant CCO:B0028341 ! Q59GI1_HUMAN relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0028354 ! ETV6_HUMAN relationship: has_participant CCO:B0028502 ! ERCC3_HUMAN relationship: has_participant CCO:B0028510 ! MYBA_HUMAN relationship: has_participant CCO:B0028677 ! PADI4_HUMAN relationship: has_participant CCO:B0028736 ! CDYL1_HUMAN relationship: has_participant CCO:B0029283 ! ZSC20_HUMAN relationship: has_participant CCO:B0029287 ! A6NJN6_HUMAN relationship: has_participant CCO:B0029479 ! LMO4_HUMAN relationship: has_participant CCO:B0029480 ! Q8NHM1_HUMAN relationship: has_participant CCO:B0029482 ! LHX3_HUMAN relationship: has_participant CCO:B0029488 ! Q9HBU2_HUMAN relationship: has_participant CCO:B0029683 ! Q56TK0_HUMAN relationship: has_participant CCO:B0029685 ! STAT6_HUMAN relationship: has_participant CCO:B0030140 ! Q5C8S5_HUMAN relationship: has_participant CCO:B0030141 ! Q0H8T6_HUMAN relationship: has_participant CCO:B0030142 ! Q9UE35_HUMAN relationship: has_participant CCO:B0030143 ! Q6MZQ9_HUMAN relationship: has_participant CCO:B0030185 ! A8MS99_HUMAN relationship: has_participant CCO:B0030312 ! ETV3_HUMAN relationship: has_participant CCO:B0030313 ! ETS1_HUMAN relationship: has_participant CCO:B0030315 ! ETV2_HUMAN relationship: has_participant CCO:B0030316 ! ETS2_HUMAN relationship: has_participant CCO:B0030317 ! Q6N087_HUMAN relationship: has_participant CCO:B0030323 ! Q3KNT2_HUMAN relationship: has_participant CCO:B0030326 ! A6NFN5_HUMAN relationship: has_participant CCO:B0030506 ! NGN2_HUMAN relationship: has_participant CCO:B0030509 ! NGN3_HUMAN relationship: has_participant CCO:B0031064 ! LIMD1_HUMAN relationship: has_participant CCO:B0031066 ! MKX_HUMAN relationship: has_participant CCO:B0031067 ! IRX5_HUMAN relationship: has_participant CCO:B0031069 ! IRX2_HUMAN relationship: has_participant CCO:B0031070 ! IRX3_HUMAN relationship: has_participant CCO:B0031071 ! IRX1_HUMAN relationship: has_participant CCO:B0031563 ! NTKL_HUMAN relationship: has_participant CCO:B0031623 ! FX4L2_HUMAN relationship: has_participant CCO:B0031624 ! FOXA1_HUMAN relationship: has_participant CCO:B0031625 ! FOXA3_HUMAN relationship: has_participant CCO:B0031646 ! 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ZN277_HUMAN relationship: has_participant CCO:B0053697 ! A0AUX1_HUMAN relationship: has_participant CCO:B0053699 ! A0AVJ9_HUMAN relationship: has_participant CCO:B0053702 ! MED19_HUMAN relationship: has_participant CCO:B0053704 ! FEZF1_HUMAN relationship: has_participant CCO:B0053707 ! A1A4T9_HUMAN relationship: has_participant CCO:B0053708 ! A1ECB1_HUMAN relationship: has_participant CCO:B0053709 ! A1ECB2_HUMAN relationship: has_participant CCO:B0053713 ! A1L4L9_HUMAN relationship: has_participant CCO:B0053715 ! A2A2C9_HUMAN relationship: has_participant CCO:B0053717 ! A2A3I7_HUMAN relationship: has_participant CCO:B0053718 ! A2A3Q3_HUMAN relationship: has_participant CCO:B0053719 ! A2A3Q4_HUMAN relationship: has_participant CCO:B0053720 ! A2A3Q5_HUMAN relationship: has_participant CCO:B0053722 ! A2ABL5_HUMAN relationship: has_participant CCO:B0053723 ! A2AGP5_HUMAN relationship: has_participant CCO:B0053729 ! A2BFK5_HUMAN relationship: has_participant CCO:B0053730 ! 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A5PKU7_HUMAN relationship: has_participant CCO:B0053776 ! A5PLP1_HUMAN relationship: has_participant CCO:B0053780 ! BDP1_HUMAN relationship: has_participant CCO:B0053785 ! NKX26_HUMAN relationship: has_participant CCO:B0053787 ! YB041_HUMAN relationship: has_participant CCO:B0053789 ! A6ND77_HUMAN relationship: has_participant CCO:B0053798 ! YT007_HUMAN relationship: has_participant CCO:B0053799 ! A6NDX7_HUMAN relationship: has_participant CCO:B0053801 ! A6NE42_HUMAN relationship: has_participant CCO:B0053808 ! SSX10_HUMAN relationship: has_participant CCO:B0053812 ! A6NF07_HUMAN relationship: has_participant CCO:B0053814 ! YS053_HUMAN relationship: has_participant CCO:B0053815 ! ZN734_HUMAN relationship: has_participant CCO:B0053819 ! HELT_HUMAN relationship: has_participant CCO:B0053820 ! A6NFE1_HUMAN relationship: has_participant CCO:B0053821 ! ZN316_HUMAN relationship: has_participant CCO:B0053823 ! DPRX_HUMAN relationship: has_participant CCO:B0053825 ! 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YI017_HUMAN relationship: has_participant CCO:B0053877 ! YM010_HUMAN relationship: has_participant CCO:B0053878 ! ZN233_HUMAN relationship: has_participant CCO:B0053881 ! A6NKB0_HUMAN relationship: has_participant CCO:B0053883 ! ARI3C_HUMAN relationship: has_participant CCO:B0053889 ! ZN733_HUMAN relationship: has_participant CCO:B0053895 ! EA3L2_HUMAN relationship: has_participant CCO:B0053896 ! A6NLG4_HUMAN relationship: has_participant CCO:B0053899 ! A6NLU7_HUMAN relationship: has_participant CCO:B0053900 ! A6NLV7_HUMAN relationship: has_participant CCO:B0053901 ! DUXA_HUMAN relationship: has_participant CCO:B0053903 ! ZFP92_HUMAN relationship: has_participant CCO:B0053905 ! A6NM80_HUMAN relationship: has_participant CCO:B0053912 ! YS032_HUMAN relationship: has_participant CCO:B0053913 ! DRGX_HUMAN relationship: has_participant CCO:B0053915 ! YS047_HUMAN relationship: has_participant CCO:B0053918 ! A6NNU8_HUMAN relationship: has_participant CCO:B0053919 ! SSX11_HUMAN relationship: has_participant CCO:B0053923 ! ZN716_HUMAN relationship: has_participant CCO:B0053924 ! A6PVD2_HUMAN relationship: has_participant CCO:B0053925 ! A6PVD3_HUMAN relationship: has_participant CCO:B0053926 ! A6PVQ1_HUMAN relationship: has_participant CCO:B0053927 ! A6PVQ2_HUMAN relationship: has_participant CCO:B0053929 ! A6PVW1_HUMAN relationship: has_participant CCO:B0053930 ! A6PVW2_HUMAN relationship: has_participant CCO:B0053931 ! A6PVW3_HUMAN relationship: has_participant CCO:B0053932 ! A6PVW4_HUMAN relationship: has_participant CCO:B0053933 ! A6PVW5_HUMAN relationship: has_participant CCO:B0053934 ! A6PVW7_HUMAN relationship: has_participant CCO:B0053940 ! A6XAE6_HUMAN relationship: has_participant CCO:B0053941 ! A6YCE1_HUMAN relationship: has_participant CCO:B0053945 ! A7E2C7_HUMAN relationship: has_participant CCO:B0053949 ! A7LQ08_HUMAN relationship: has_participant CCO:B0053950 ! A7XAK3_HUMAN relationship: has_participant CCO:B0053952 ! 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A8MTK7_HUMAN relationship: has_participant CCO:B0054030 ! A8MTL8_HUMAN relationship: has_participant CCO:B0054033 ! NOTO_HUMAN relationship: has_participant CCO:B0054034 ! A8MTT8_HUMAN relationship: has_participant CCO:B0054035 ! YS033_HUMAN relationship: has_participant CCO:B0054040 ! A8MUG1_HUMAN relationship: has_participant CCO:B0054048 ! ZN735_HUMAN relationship: has_participant CCO:B0054051 ! Z705G_HUMAN relationship: has_participant CCO:B0054054 ! A8MV38_HUMAN relationship: has_participant CCO:B0054055 ! A8MV43_HUMAN relationship: has_participant CCO:B0054056 ! VGLL3_HUMAN relationship: has_participant CCO:B0054057 ! A8MVA1_HUMAN relationship: has_participant CCO:B0054059 ! A8MVM0_HUMAN relationship: has_participant CCO:B0054063 ! YA035_HUMAN relationship: has_participant CCO:B0054065 ! Z705F_HUMAN relationship: has_participant CCO:B0054069 ! A8MVX5_HUMAN relationship: has_participant CCO:B0054070 ! A8MVZ3_HUMAN relationship: has_participant CCO:B0054071 ! A8MW10_HUMAN relationship: has_participant CCO:B0054074 ! A8MW67_HUMAN relationship: has_participant CCO:B0054075 ! A8MW73_HUMAN relationship: has_participant CCO:B0054076 ! A8MW98_HUMAN relationship: has_participant CCO:B0054077 ! Z705H_HUMAN relationship: has_participant CCO:B0054078 ! A8MWF9_HUMAN relationship: has_participant CCO:B0054081 ! A8MWR6_HUMAN relationship: has_participant CCO:B0054083 ! A8MWV7_HUMAN relationship: has_participant CCO:B0054085 ! A8MWY6_HUMAN relationship: has_participant CCO:B0054087 ! A8MX14_HUMAN relationship: has_participant CCO:B0054088 ! A8MX22_HUMAN relationship: has_participant CCO:B0054089 ! A8MX31_HUMAN relationship: has_participant CCO:B0054090 ! A8MX39_HUMAN relationship: has_participant CCO:B0054092 ! A8MX67_HUMAN relationship: has_participant CCO:B0054102 ! A8MXS9_HUMAN relationship: has_participant CCO:B0054107 ! A8MXY6_HUMAN relationship: has_participant CCO:B0054110 ! A8MY01_HUMAN relationship: has_participant CCO:B0054112 ! A8MY44_HUMAN relationship: has_participant CCO:B0054113 ! A8MY63_HUMAN relationship: has_participant CCO:B0054115 ! A8MY82_HUMAN relationship: has_participant CCO:B0054119 ! A8MY91_HUMAN relationship: has_participant CCO:B0054120 ! A8MYD4_HUMAN relationship: has_participant CCO:B0054121 ! YA039_HUMAN relationship: has_participant CCO:B0054122 ! A8MYG0_HUMAN relationship: has_participant CCO:B0054123 ! A8MYJ4_HUMAN relationship: has_participant CCO:B0054124 ! A8MYJ5_HUMAN relationship: has_participant CCO:B0054125 ! A8MYM2_HUMAN relationship: has_participant CCO:B0054128 ! A8MYS6_HUMAN relationship: has_participant CCO:B0054129 ! A8MYT0_HUMAN relationship: has_participant CCO:B0054131 ! A8MYT8_HUMAN relationship: has_participant CCO:B0054137 ! LEUTX_HUMAN relationship: has_participant CCO:B0054139 ! A8MZF2_HUMAN relationship: has_participant CCO:B0054140 ! A8MZF4_HUMAN relationship: has_participant CCO:B0054145 ! A8VJE6_HUMAN relationship: has_participant CCO:B0054146 ! 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BRAC_HUMAN relationship: has_participant CCO:B0054414 ! SMAD9_HUMAN relationship: has_participant CCO:B0054415 ! ZBT22_HUMAN relationship: has_participant CCO:B0054422 ! SHOX_HUMAN relationship: has_participant CCO:B0054431 ! FOXN1_HUMAN relationship: has_participant CCO:B0054435 ! TOX3_HUMAN relationship: has_participant CCO:B0054439 ! GSC2_HUMAN relationship: has_participant CCO:B0054445 ! PER1_HUMAN relationship: has_participant CCO:B0054446 ! ZN193_HUMAN relationship: has_participant CCO:B0054453 ! ZBT24_HUMAN relationship: has_participant CCO:B0054456 ! CRX_HUMAN relationship: has_participant CCO:B0054461 ! O43245_HUMAN relationship: has_participant CCO:B0054462 ! HXC11_HUMAN relationship: has_participant CCO:B0054467 ! ZN264_HUMAN relationship: has_participant CCO:B0054468 ! ZBT43_HUMAN relationship: has_participant CCO:B0054470 ! ZSC12_HUMAN relationship: has_participant CCO:B0054471 ! PAX4_HUMAN relationship: has_participant CCO:B0054473 ! 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ZF161_HUMAN relationship: has_participant CCO:B0054524 ! ZNF73_HUMAN relationship: has_participant CCO:B0054525 ! O43831_HUMAN relationship: has_participant CCO:B0054531 ! AIRE_HUMAN relationship: has_participant CCO:B0054532 ! SSX4_HUMAN relationship: has_participant CCO:B0054533 ! SSX5_HUMAN relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0054539 ! ZN292_HUMAN relationship: has_participant CCO:B0054540 ! ST18_HUMAN relationship: has_participant CCO:B0054541 ! ZN862_HUMAN relationship: has_participant CCO:B0054543 ! ZN500_HUMAN relationship: has_participant CCO:B0054546 ! ZEB2_HUMAN relationship: has_participant CCO:B0054551 ! NOBOX_HUMAN relationship: has_participant CCO:B0054568 ! O60587_HUMAN relationship: has_participant CCO:B0054571 ! PDE8A_HUMAN relationship: has_participant CCO:B0054572 ! LMX1B_HUMAN relationship: has_participant CCO:B0054575 ! MUSC_HUMAN relationship: has_participant CCO:B0054579 ! Z354A_HUMAN relationship: has_participant CCO:B0054580 ! TBX19_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN relationship: has_participant CCO:B0054588 ! SHOX2_HUMAN relationship: has_participant CCO:B0054590 ! TBL1X_HUMAN relationship: has_participant CCO:B0054595 ! MITF_HUMAN relationship: has_participant CCO:B0054601 ! MTG16_HUMAN relationship: has_participant CCO:B0054603 ! ZN623_HUMAN relationship: has_participant CCO:B0054606 ! CAND2_HUMAN relationship: has_participant CCO:B0054607 ! T22D2_HUMAN relationship: has_participant CCO:B0054610 ! JHD3A_HUMAN relationship: has_participant CCO:B0054611 ! CNOT3_HUMAN relationship: has_participant CCO:B0054614 ! Z780A_HUMAN relationship: has_participant CCO:B0054616 ! O75321_HUMAN relationship: has_participant CCO:B0054620 ! ZN253_HUMAN relationship: has_participant CCO:B0054622 ! PROP1_HUMAN relationship: has_participant CCO:B0054623 ! ZN217_HUMAN relationship: has_participant CCO:B0054624 ! PITX3_HUMAN relationship: has_participant CCO:B0054626 ! NCOR1_HUMAN relationship: has_participant CCO:B0054629 ! TULP3_HUMAN relationship: has_participant CCO:B0054631 ! DEAF1_HUMAN relationship: has_participant CCO:B0054635 ! ZN254_HUMAN relationship: has_participant CCO:B0054637 ! SAP30_HUMAN relationship: has_participant CCO:B0054638 ! Z324A_HUMAN relationship: has_participant CCO:B0054639 ! NR1I2_HUMAN relationship: has_participant CCO:B0054642 ! PSIP1_HUMAN relationship: has_participant CCO:B0054645 ! DUX2_HUMAN relationship: has_participant CCO:B0054648 ! CSDE1_HUMAN relationship: has_participant CCO:B0054649 ! ZN821_HUMAN relationship: has_participant CCO:B0054653 ! KS6A5_HUMAN relationship: has_participant CCO:B0054654 ! MYCB2_HUMAN relationship: has_participant CCO:B0054655 ! FOXH1_HUMAN relationship: has_participant CCO:B0054656 ! GCM2_HUMAN relationship: has_participant CCO:B0054658 ! PRDM1_HUMAN relationship: has_participant CCO:B0054669 ! O75806_HUMAN relationship: has_participant CCO:B0054671 ! ZN189_HUMAN relationship: has_participant CCO:B0054673 ! KLF7_HUMAN relationship: has_participant CCO:B0054683 ! SNPC5_HUMAN relationship: has_participant CCO:B0054690 ! S14L2_HUMAN relationship: has_participant CCO:B0054698 ! MTA2_HUMAN relationship: has_participant CCO:B0054703 ! TOX4_HUMAN relationship: has_participant CCO:B0054706 ! ZN432_HUMAN relationship: has_participant CCO:B0054707 ! TOX_HUMAN relationship: has_participant CCO:B0054711 ! FRYL_HUMAN relationship: has_participant CCO:B0054712 ! NFAT5_HUMAN relationship: has_participant CCO:B0054713 ! JHD3B_HUMAN relationship: has_participant CCO:B0054714 ! CMTA2_HUMAN relationship: has_participant CCO:B0054720 ! FSBP_HUMAN relationship: has_participant CCO:B0054721 ! ALX3_HUMAN relationship: has_participant CCO:B0054723 ! NKX22_HUMAN relationship: has_participant CCO:B0054725 ! ZN202_HUMAN relationship: has_participant CCO:B0054726 ! O95133_HUMAN relationship: has_participant CCO:B0054735 ! ZN205_HUMAN relationship: has_participant CCO:B0054738 ! VENTX_HUMAN relationship: has_participant CCO:B0054739 ! SPDEF_HUMAN relationship: has_participant CCO:B0054741 ! KCNH1_HUMAN relationship: has_participant CCO:B0054742 ! PDE8B_HUMAN relationship: has_participant CCO:B0054749 ! SIX3_HUMAN relationship: has_participant CCO:B0054751 ! ZBT7A_HUMAN relationship: has_participant CCO:B0054766 ! SIX6_HUMAN relationship: has_participant CCO:B0054770 ! CBX6_HUMAN relationship: has_participant CCO:B0054772 ! KLF8_HUMAN relationship: has_participant CCO:B0054774 ! ZBT11_HUMAN relationship: has_participant CCO:B0054775 ! CNOT4_HUMAN relationship: has_participant CCO:B0054779 ! NFAC1_HUMAN relationship: has_participant CCO:B0054782 ! EYA4_HUMAN relationship: has_participant CCO:B0054805 ! CBX7_HUMAN relationship: has_participant CCO:B0054806 ! EOMES_HUMAN relationship: has_participant CCO:B0054814 ! MBD3_HUMAN relationship: has_participant CCO:B0054819 ! HAND1_HUMAN relationship: has_participant CCO:B0054823 ! NSD2_HUMAN relationship: has_participant CCO:B0054833 ! FOS_HUMAN relationship: has_participant CCO:B0054886 ! GCR_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN relationship: has_participant CCO:B0054898 ! HMGN2_HUMAN relationship: has_participant CCO:B0054904 ! PRGR_HUMAN relationship: has_participant CCO:B0054918 ! ZFY_HUMAN relationship: has_participant CCO:B0054922 ! GLI1_HUMAN relationship: has_participant CCO:B0054925 ! MCR_HUMAN relationship: has_participant CCO:B0054940 ! PO2F2_HUMAN relationship: has_participant CCO:B0054962 ! GLP1_HUMAN relationship: has_participant CCO:B0054963 ! RHF2B_HUMAN relationship: has_participant CCO:B0054965 ! GLI2_HUMAN relationship: has_participant CCO:B0054966 ! HKR1_HUMAN relationship: has_participant CCO:B0054967 ! ZSC22_HUMAN relationship: has_participant CCO:B0054968 ! ZBT48_HUMAN relationship: has_participant CCO:B0054978 ! THA_HUMAN relationship: has_participant CCO:B0054979 ! THB_HUMAN relationship: has_participant CCO:B0054991 ! ERG_HUMAN relationship: has_participant CCO:B0054992 ! VDR_HUMAN relationship: has_participant CCO:B0055000 ! MYCL1_HUMAN relationship: has_participant CCO:B0055001 ! MYCL2_HUMAN relationship: has_participant CCO:B0055008 ! LYL1_HUMAN relationship: has_participant CCO:B0055009 ! NR2C1_HUMAN relationship: has_participant CCO:B0055012 ! MYF5_HUMAN relationship: has_participant CCO:B0055017 ! ZNF35_HUMAN relationship: has_participant CCO:B0055022 ! IRF2_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0055026 ! HXB3_HUMAN relationship: has_participant CCO:B0055027 ! HXB2_HUMAN relationship: has_participant CCO:B0055028 ! HXB1_HUMAN relationship: has_participant CCO:B0055031 ! MYOG_HUMAN relationship: has_participant CCO:B0055036 ! FOSL2_HUMAN relationship: has_participant CCO:B0055040 ! ZNF44_HUMAN relationship: has_participant CCO:B0055041 ! ZN250_HUMAN relationship: has_participant CCO:B0055042 ! ZEP1_HUMAN relationship: has_participant CCO:B0055043 ! PAX1_HUMAN relationship: has_participant CCO:B0055045 ! GATA1_HUMAN relationship: has_participant CCO:B0055049 ! GCF_HUMAN relationship: has_participant CCO:B0055050 ! ZN823_HUMAN relationship: has_participant CCO:B0055062 ! ZFX_HUMAN relationship: has_participant CCO:B0055063 ! ZNF12_HUMAN relationship: has_participant CCO:B0055064 ! ZNF14_HUMAN relationship: has_participant CCO:B0055065 ! ZN708_HUMAN relationship: has_participant CCO:B0055066 ! ZNF16_HUMAN relationship: has_participant CCO:B0055067 ! ZNF17_HUMAN relationship: has_participant CCO:B0055068 ! ZNF18_HUMAN relationship: has_participant CCO:B0055069 ! ZNF20_HUMAN relationship: has_participant CCO:B0055070 ! ZN182_HUMAN relationship: has_participant CCO:B0055071 ! ZNF22_HUMAN relationship: has_participant CCO:B0055072 ! ZNF23_HUMAN relationship: has_participant CCO:B0055073 ! ZKSC1_HUMAN relationship: has_participant CCO:B0055074 ! ZNF25_HUMAN relationship: has_participant CCO:B0055075 ! ZN37A_HUMAN relationship: has_participant CCO:B0055076 ! ZNF28_HUMAN relationship: has_participant CCO:B0055077 ! ZNF3_HUMAN relationship: has_participant CCO:B0055078 ! ZNF43_HUMAN relationship: has_participant CCO:B0055079 ! ZNF30_HUMAN relationship: has_participant CCO:B0055080 ! ZNF32_HUMAN relationship: has_participant CCO:B0055082 ! HMGA1_HUMAN relationship: has_participant CCO:B0055083 ! ZNF8_HUMAN relationship: has_participant CCO:B0055088 ! UBF1_HUMAN relationship: has_participant CCO:B0055089 ! JUND_HUMAN relationship: has_participant CCO:B0055090 ! TAL1_HUMAN relationship: has_participant CCO:B0055093 ! XBP1_HUMAN relationship: has_participant CCO:B0055095 ! SPI1_HUMAN relationship: has_participant CCO:B0055100 ! EGR1_HUMAN relationship: has_participant CCO:B0055102 ! NELFE_HUMAN relationship: has_participant CCO:B0055105 ! ATF1_HUMAN relationship: has_participant CCO:B0055109 ! HME2_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0055121 ! NR1D1_HUMAN relationship: has_participant CCO:B0055132 ! ZNF10_HUMAN relationship: has_participant CCO:B0055146 ! USF1_HUMAN relationship: has_participant CCO:B0055150 ! NR4A1_HUMAN relationship: has_participant CCO:B0055153 ! TCEA1_HUMAN relationship: has_participant CCO:B0055156 ! MYF6_HUMAN relationship: has_participant CCO:B0055159 ! SP100_HUMAN relationship: has_participant CCO:B0055163 ! PAX7_HUMAN relationship: has_participant CCO:B0055164 ! PAX3_HUMAN relationship: has_participant CCO:B0055165 ! GATA2_HUMAN relationship: has_participant CCO:B0055166 ! GATA3_HUMAN relationship: has_participant CCO:B0055169 ! ZBT25_HUMAN relationship: has_participant CCO:B0055200 ! ELK4_HUMAN relationship: has_participant CCO:B0055202 ! HXD10_HUMAN relationship: has_participant CCO:B0055203 ! MSX1_HUMAN relationship: has_participant CCO:B0055204 ! SMCA1_HUMAN relationship: has_participant CCO:B0055206 ! MZF1_HUMAN relationship: has_participant CCO:B0055208 ! T2EA_HUMAN relationship: has_participant CCO:B0055209 ! T2EB_HUMAN relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN relationship: has_participant CCO:B0055212 ! RABP2_HUMAN relationship: has_participant CCO:B0055213 ! JAD1A_HUMAN relationship: has_participant CCO:B0055234 ! HXD3_HUMAN relationship: has_participant CCO:B0055235 ! HXA10_HUMAN relationship: has_participant CCO:B0055236 ! HXA9_HUMAN relationship: has_participant CCO:B0055237 ! HXA11_HUMAN relationship: has_participant CCO:B0055238 ! HXA13_HUMAN relationship: has_participant CCO:B0055239 ! HXC9_HUMAN relationship: has_participant CCO:B0055240 ! HXC12_HUMAN relationship: has_participant CCO:B0055241 ! HXC13_HUMAN relationship: has_participant CCO:B0055242 ! HXD11_HUMAN relationship: has_participant CCO:B0055243 ! TLX1_HUMAN relationship: has_participant CCO:B0055245 ! ZEP2_HUMAN relationship: has_participant CCO:B0055254 ! OTX1_HUMAN relationship: has_participant CCO:B0055255 ! OTX2_HUMAN relationship: has_participant CCO:B0055279 ! BMI1_HUMAN relationship: has_participant CCO:B0055280 ! PCGF2_HUMAN relationship: has_participant CCO:B0055283 ! ZN123_HUMAN relationship: has_participant CCO:B0055284 ! ZN125_HUMAN relationship: has_participant CCO:B0055285 ! ZN126_HUMAN relationship: has_participant CCO:B0055291 ! HXD12_HUMAN relationship: has_participant CCO:B0055292 ! HXD13_HUMAN relationship: has_participant CCO:B0055294 ! MSX2_HUMAN relationship: has_participant CCO:B0055299 ! HNF1B_HUMAN relationship: has_participant CCO:B0055300 ! SOX5_HUMAN relationship: has_participant CCO:B0055301 ! SOX6_HUMAN relationship: has_participant CCO:B0055302 ! ZNF93_HUMAN relationship: has_participant CCO:B0055306 ! TCF7_HUMAN relationship: has_participant CCO:B0055309 ! ZNF76_HUMAN relationship: has_participant CCO:B0055317 ! ZEB1_HUMAN relationship: has_participant CCO:B0055321 ! SMBP2_HUMAN relationship: has_participant CCO:B0055329 ! PBX1_HUMAN relationship: has_participant CCO:B0055330 ! PBX3_HUMAN relationship: has_participant CCO:B0055334 ! ETV5_HUMAN relationship: has_participant CCO:B0055337 ! JAD1C_HUMAN relationship: has_participant CCO:B0055345 ! ELK3_HUMAN relationship: has_participant CCO:B0055362 ! ETV4_HUMAN relationship: has_participant CCO:B0055363 ! NR4A2_HUMAN relationship: has_participant CCO:B0055369 ! GATA4_HUMAN relationship: has_participant CCO:B0055370 ! NKX21_HUMAN relationship: has_participant CCO:B0055402 ! RFX5_HUMAN relationship: has_participant CCO:B0055403 ! SOX9_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN relationship: has_participant CCO:B0055411 ! LHX1_HUMAN relationship: has_participant CCO:B0055416 ! NR2C2_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN relationship: has_participant CCO:B0055427 ! EVX1_HUMAN relationship: has_participant CCO:B0055431 ! CEBPA_HUMAN relationship: has_participant CCO:B0055432 ! CEBPD_HUMAN relationship: has_participant CCO:B0055440 ! TAF6_HUMAN relationship: has_participant CCO:B0055441 ! ZN165_HUMAN relationship: has_participant CCO:B0055445 ! MEOX1_HUMAN relationship: has_participant CCO:B0055451 ! LHX2_HUMAN relationship: has_participant CCO:B0055452 ! ETV1_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN relationship: has_participant CCO:B0055465 ! RORG_HUMAN relationship: has_participant CCO:B0055466 ! ZNF80_HUMAN relationship: has_participant CCO:B0055467 ! ZNF84_HUMAN relationship: has_participant CCO:B0055470 ! MECP2_HUMAN relationship: has_participant CCO:B0055478 ! ZN157_HUMAN relationship: has_participant CCO:B0055481 ! ZNF41_HUMAN relationship: has_participant CCO:B0055482 ! AFF3_HUMAN relationship: has_participant CCO:B0055483 ! NR0B1_HUMAN relationship: has_participant CCO:B0055484 ! HDGF_HUMAN relationship: has_participant CCO:B0055488 ! TF2AA_HUMAN relationship: has_participant CCO:B0055490 ! ZN133_HUMAN relationship: has_participant CCO:B0055491 ! ZN136_HUMAN relationship: has_participant CCO:B0055492 ! ZN140_HUMAN relationship: has_participant CCO:B0055493 ! ZN131_HUMAN relationship: has_participant CCO:B0055494 ! ZN132_HUMAN relationship: has_participant CCO:B0055495 ! ZN135_HUMAN relationship: has_participant CCO:B0055496 ! ZN137_HUMAN relationship: has_participant CCO:B0055497 ! ZN138_HUMAN relationship: has_participant CCO:B0055498 ! ZN142_HUMAN relationship: has_participant CCO:B0055499 ! ZN143_HUMAN relationship: has_participant CCO:B0055506 ! NKX25_HUMAN relationship: has_participant CCO:B0055507 ! LBX1_HUMAN relationship: has_participant CCO:B0055517 ! PRRX1_HUMAN relationship: has_participant CCO:B0055518 ! NRL_HUMAN relationship: has_participant CCO:B0055525 ! NR1H2_HUMAN relationship: has_participant CCO:B0055529 ! ELL_HUMAN relationship: has_participant CCO:B0055535 ! PKNX1_HUMAN relationship: has_participant CCO:B0055536 ! PAX9_HUMAN relationship: has_participant CCO:B0055539 ! DLX1_HUMAN relationship: has_participant CCO:B0055543 ! MAZ_HUMAN relationship: has_participant CCO:B0055547 ! SOX10_HUMAN relationship: has_participant CCO:B0055553 ! GSC_HUMAN relationship: has_participant CCO:B0055556 ! PRD15_HUMAN relationship: has_participant CCO:B0055557 ! SOX8_HUMAN relationship: has_participant CCO:B0055559 ! KLF3_HUMAN relationship: has_participant CCO:B0055569 ! VSX2_HUMAN relationship: has_participant CCO:B0055570 ! ZN121_HUMAN relationship: has_participant CCO:B0055590 ! Z280A_HUMAN relationship: has_participant CCO:B0055593 ! ZN445_HUMAN relationship: has_participant CCO:B0055594 ! ELOF1_HUMAN relationship: has_participant CCO:B0055608 ! HAND2_HUMAN relationship: has_participant CCO:B0055610 ! ISL1_HUMAN relationship: has_participant CCO:B0055618 ! TBPL1_HUMAN relationship: has_participant CCO:B0055620 ! CNBP_HUMAN relationship: has_participant CCO:B0055638 ! PITX1_HUMAN relationship: has_participant CCO:B0055642 ! NKX32_HUMAN relationship: has_participant CCO:B0055643 ! IRX6_HUMAN relationship: has_participant CCO:B0055644 ! IRX4_HUMAN relationship: has_participant CCO:B0055646 ! PO6F2_HUMAN relationship: has_participant CCO:B0055649 ! BTG2_HUMAN relationship: has_participant CCO:B0055650 ! ELF3_HUMAN relationship: has_participant CCO:B0055654 ! SIM1_HUMAN relationship: has_participant CCO:B0055657 ! NSBP1_HUMAN relationship: has_participant CCO:B0055658 ! HCC1_HUMAN relationship: has_participant CCO:B0055663 ! LBXCO_HUMAN relationship: has_participant CCO:B0055672 ! ZXDA_HUMAN relationship: has_participant CCO:B0055673 ! ZXDB_HUMAN relationship: has_participant CCO:B0055678 ! TFAM_HUMAN relationship: has_participant CCO:B0055679 ! PURA_HUMAN relationship: has_participant CCO:B0055685 ! INSM1_HUMAN relationship: has_participant CCO:B0055690 ! FLI1_HUMAN relationship: has_participant CCO:B0055692 ! NC2B_HUMAN relationship: has_participant CCO:B0055693 ! TFAP4_HUMAN relationship: has_participant CCO:B0055695 ! SPIB_HUMAN relationship: has_participant CCO:B0055701 ! SF17A_HUMAN relationship: has_participant CCO:B0055702 ! MEF2A_HUMAN relationship: has_participant CCO:B0055703 ! MEF2B_HUMAN relationship: has_participant CCO:B0055704 ! SP2_HUMAN relationship: has_participant CCO:B0055708 ! ZNF45_HUMAN relationship: has_participant CCO:B0055709 ! SP4_HUMAN relationship: has_participant CCO:B0055710 ! SP3_HUMAN relationship: has_participant CCO:B0055711 ! HEN1_HUMAN relationship: has_participant CCO:B0055712 ! HEN2_HUMAN relationship: has_participant CCO:B0055716 ! RASF7_HUMAN relationship: has_participant CCO:B0055717 ! RL6_HUMAN relationship: has_participant CCO:B0055719 ! CREM_HUMAN relationship: has_participant CCO:B0055720 ! ENL_HUMAN relationship: has_participant CCO:B0055722 ! PPARD_HUMAN relationship: has_participant CCO:B0055725 ! ERCC6_HUMAN relationship: has_participant CCO:B0055726 ! EVX2_HUMAN relationship: has_participant CCO:B0055727 ! ZNF85_HUMAN relationship: has_participant CCO:B0055728 ! ZN117_HUMAN relationship: has_participant CCO:B0055729 ! ZNF90_HUMAN relationship: has_participant CCO:B0055730 ! ARI5A_HUMAN relationship: has_participant CCO:B0055733 ! EMX1_HUMAN relationship: has_participant CCO:B0055734 ! EMX2_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0055741 ! EGR4_HUMAN relationship: has_participant CCO:B0055742 ! ZNF91_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN relationship: has_participant CCO:B0055746 ! HME1_HUMAN relationship: has_participant CCO:B0055749 ! Q05BE4_HUMAN relationship: has_participant CCO:B0055751 ! Q05BS4_HUMAN relationship: has_participant CCO:B0055754 ! Q05BY5_HUMAN relationship: has_participant CCO:B0055755 ! Q05C29_HUMAN relationship: has_participant CCO:B0055757 ! Q05CQ7_HUMAN relationship: has_participant CCO:B0055758 ! Q05CR2_HUMAN relationship: has_participant CCO:B0055760 ! Q05D58_HUMAN relationship: has_participant CCO:B0055762 ! Q05DA6_HUMAN relationship: has_participant CCO:B0055763 ! Q05DF4_HUMAN relationship: has_participant CCO:B0055764 ! Q05DL7_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN relationship: has_participant CCO:B0055768 ! MEF2C_HUMAN relationship: has_participant CCO:B0055769 ! MTG8_HUMAN relationship: has_participant CCO:B0055771 ! PAX8_HUMAN relationship: has_participant CCO:B0055772 ! ZN33A_HUMAN relationship: has_participant CCO:B0055773 ! ZN33B_HUMAN relationship: has_participant CCO:B0055776 ! EGR3_HUMAN relationship: has_participant CCO:B0055778 ! Q06DQ3_HUMAN relationship: has_participant CCO:B0055786 ! PPARA_HUMAN relationship: has_participant CCO:B0055788 ! FOXM1_HUMAN relationship: has_participant CCO:B0055798 ! ZN844_HUMAN relationship: has_participant CCO:B0055803 ! ZN543_HUMAN relationship: has_participant CCO:B0055806 ! ZN415_HUMAN relationship: has_participant CCO:B0055808 ! ZN763_HUMAN relationship: has_participant CCO:B0055809 ! RIPP1_HUMAN relationship: has_participant CCO:B0055811 ! Q0GM61_HUMAN relationship: has_participant CCO:B0055815 ! Q0P5U9_HUMAN relationship: has_participant CCO:B0055816 ! Q0P6G1_HUMAN relationship: has_participant CCO:B0055820 ! Q0VAC9_HUMAN relationship: has_participant CCO:B0055821 ! Q0VAJ6_HUMAN relationship: has_participant CCO:B0055825 ! Q0VFW9_HUMAN relationship: has_participant CCO:B0055827 ! MESP2_HUMAN relationship: has_participant CCO:B0055834 ! DBP_HUMAN relationship: has_participant CCO:B0055835 ! TEF_HUMAN relationship: has_participant CCO:B0055837 ! SMF_HUMAN relationship: has_participant CCO:B0055841 ! PNRC1_HUMAN relationship: has_participant CCO:B0055842 ! TFCP2_HUMAN relationship: has_participant CCO:B0055844 ! KCNH2_HUMAN relationship: has_participant CCO:B0055846 ! BPTF_HUMAN relationship: has_participant CCO:B0055847 ! PO4F2_HUMAN relationship: has_participant CCO:B0055852 ! TCF15_HUMAN relationship: has_participant CCO:B0055853 ! SFRS8_HUMAN relationship: has_participant CCO:B0055854 ! ZN155_HUMAN relationship: has_participant CCO:B0055855 ! ILF2_HUMAN relationship: has_participant CCO:B0055858 ! ELAV2_HUMAN relationship: has_participant CCO:B0055859 ! NFAC3_HUMAN relationship: has_participant CCO:B0055860 ! PP1R8_HUMAN relationship: has_participant CCO:B0055863 ! NFX1_HUMAN relationship: has_participant CCO:B0055868 ! PRDM2_HUMAN relationship: has_participant CCO:B0055869 ! FLII_HUMAN relationship: has_participant CCO:B0055875 ! KLF10_HUMAN relationship: has_participant CCO:B0055876 ! REST_HUMAN relationship: has_participant CCO:B0055877 ! RLF_HUMAN relationship: has_participant CCO:B0055878 ! NR1H3_HUMAN relationship: has_participant CCO:B0055884 ! CBX3_HUMAN relationship: has_participant CCO:B0055886 ! TBX2_HUMAN relationship: has_participant CCO:B0055887 ! ERCC8_HUMAN relationship: has_participant CCO:B0055892 ! STF1_HUMAN relationship: has_participant CCO:B0055899 ! MTA1_HUMAN relationship: has_participant CCO:B0055900 ! KLF1_HUMAN relationship: has_participant CCO:B0055901 ! ZN177_HUMAN relationship: has_participant CCO:B0055906 ! PM2L3_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN relationship: has_participant CCO:B0055915 ! SNPC2_HUMAN relationship: has_participant CCO:B0055920 ! NAB1_HUMAN relationship: has_participant CCO:B0055921 ! OLIG2_HUMAN relationship: has_participant CCO:B0055929 ! NDF1_HUMAN relationship: has_participant CCO:B0055949 ! KLF9_HUMAN relationship: has_participant CCO:B0055950 ! KLF5_HUMAN relationship: has_participant CCO:B0055951 ! BT3L2_HUMAN relationship: has_participant CCO:B0055952 ! C1D_HUMAN relationship: has_participant CCO:B0055958 ! VEZF1_HUMAN relationship: has_participant CCO:B0055960 ! VGLL4_HUMAN relationship: has_participant CCO:B0055961 ! SRTD2_HUMAN relationship: has_participant CCO:B0055962 ! KEAP1_HUMAN relationship: has_participant CCO:B0055964 ! SAFB2_HUMAN relationship: has_participant CCO:B0055969 ! SIM2_HUMAN relationship: has_participant CCO:B0055974 ! ELOA1_HUMAN relationship: has_participant CCO:B0055980 ! Q14333_HUMAN relationship: has_participant CCO:B0055986 ! HES1_HUMAN relationship: has_participant CCO:B0055987 ! RBM39_HUMAN relationship: has_participant CCO:B0055988 ! Q14501_HUMAN relationship: has_participant CCO:B0055989 ! HLTF_HUMAN relationship: has_participant CCO:B0055991 ! Q14547_HUMAN relationship: has_participant CCO:B0055992 ! 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PO6F1_HUMAN relationship: has_participant CCO:B0056022 ! MTF1_HUMAN relationship: has_participant CCO:B0056024 ! Q14901_HUMAN relationship: has_participant CCO:B0056025 ! ZN169_HUMAN relationship: has_participant CCO:B0056026 ! NFAC4_HUMAN relationship: has_participant CCO:B0056030 ! NR1I3_HUMAN relationship: has_participant CCO:B0056031 ! NR1D2_HUMAN relationship: has_participant CCO:B0056035 ! Q14DW8_HUMAN relationship: has_participant CCO:B0056036 ! SUZ12_HUMAN relationship: has_participant CCO:B0056041 ! OZF_HUMAN relationship: has_participant CCO:B0056048 ! TCAL1_HUMAN relationship: has_participant CCO:B0056051 ! NKX11_HUMAN relationship: has_participant CCO:B0056055 ! Q15299_HUMAN relationship: has_participant CCO:B0056056 ! IRF4_HUMAN relationship: has_participant CCO:B0056062 ! SAFB1_HUMAN relationship: has_participant CCO:B0056067 ! NR0B2_HUMAN relationship: has_participant CCO:B0056069 ! SIX1_HUMAN relationship: has_participant CCO:B0056072 ! TAF11_HUMAN relationship: has_participant CCO:B0056073 ! TAF7_HUMAN relationship: has_participant CCO:B0056074 ! Q15552_HUMAN relationship: has_participant CCO:B0056075 ! TAF1A_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0056083 ! Q15625_HUMAN relationship: has_participant CCO:B0056084 ! Q15626_HUMAN relationship: has_participant CCO:B0056085 ! Q15627_HUMAN relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0056088 ! Q15636_HUMAN relationship: has_participant CCO:B0056089 ! SF01_HUMAN relationship: has_participant CCO:B0056091 ! ZNHI3_HUMAN relationship: has_participant CCO:B0056092 ! TRIP4_HUMAN relationship: has_participant CCO:B0056093 ! JHD2C_HUMAN relationship: has_participant CCO:B0056095 ! TWST1_HUMAN relationship: has_participant CCO:B0056096 ! ZN174_HUMAN relationship: has_participant CCO:B0056097 ! ALX1_HUMAN relationship: has_participant CCO:B0056098 ! T22D1_HUMAN relationship: has_participant CCO:B0056101 ! ELF2_HUMAN relationship: has_participant CCO:B0056102 ! NAB2_HUMAN relationship: has_participant CCO:B0056103 ! CEBPE_HUMAN relationship: has_participant CCO:B0056110 ! ZN192_HUMAN relationship: has_participant CCO:B0056111 ! NDF2_HUMAN relationship: has_participant CCO:B0056112 ! NCOA1_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056114 ! SMAD1_HUMAN relationship: has_participant CCO:B0056117 ! USF2_HUMAN relationship: has_participant CCO:B0056118 ! ZFHX3_HUMAN relationship: has_participant CCO:B0056119 ! ZBTB6_HUMAN relationship: has_participant CCO:B0056120 ! ZN141_HUMAN relationship: has_participant CCO:B0056121 ! ZNF77_HUMAN relationship: has_participant CCO:B0056122 ! ZNF79_HUMAN relationship: has_participant CCO:B0056123 ! ZN124_HUMAN relationship: has_participant CCO:B0056128 ! Q16219_HUMAN relationship: has_participant CCO:B0056129 ! 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OLIG1_HUMAN relationship: has_participant CCO:B0057890 ! LMO3_HUMAN relationship: has_participant CCO:B0057891 ! ZN420_HUMAN relationship: has_participant CCO:B0057892 ! NKX23_HUMAN relationship: has_participant CCO:B0057893 ! ZN417_HUMAN relationship: has_participant CCO:B0057895 ! ZN671_HUMAN relationship: has_participant CCO:B0057899 ! ZN519_HUMAN relationship: has_participant CCO:B0057901 ! ZSC18_HUMAN relationship: has_participant CCO:B0057903 ! Q8TBJ3_HUMAN relationship: has_participant CCO:B0057904 ! FEZF2_HUMAN relationship: has_participant CCO:B0057907 ! Q8TBS2_HUMAN relationship: has_participant CCO:B0057908 ! ZN502_HUMAN relationship: has_participant CCO:B0057909 ! ZN564_HUMAN relationship: has_participant CCO:B0057911 ! ZN596_HUMAN relationship: has_participant CCO:B0057912 ! Q8TC43_HUMAN relationship: has_participant CCO:B0057915 ! ZN507_HUMAN relationship: has_participant CCO:B0057920 ! ZN398_HUMAN relationship: has_participant CCO:B0057921 ! CHD6_HUMAN relationship: has_participant CCO:B0057922 ! KLF14_HUMAN relationship: has_participant CCO:B0057925 ! DDX54_HUMAN relationship: has_participant CCO:B0057926 ! SP7_HUMAN relationship: has_participant CCO:B0057928 ! CHD5_HUMAN relationship: has_participant CCO:B0057931 ! Q8TDS3_HUMAN relationship: has_participant CCO:B0057948 ! DERP6_HUMAN relationship: has_participant CCO:B0057949 ! LMX1A_HUMAN relationship: has_participant CCO:B0057951 ! GRHL3_HUMAN relationship: has_participant CCO:B0057958 ! CR3L4_HUMAN relationship: has_participant CCO:B0057960 ! ZN721_HUMAN relationship: has_participant CCO:B0057962 ! ZN483_HUMAN relationship: has_participant CCO:B0057963 ! ZN418_HUMAN relationship: has_participant CCO:B0057964 ! ZFP90_HUMAN relationship: has_participant CCO:B0057965 ! ZN526_HUMAN relationship: has_participant CCO:B0057966 ! ZN384_HUMAN relationship: has_participant CCO:B0057971 ! ZN473_HUMAN relationship: has_participant CCO:B0057972 ! SETD7_HUMAN relationship: has_participant CCO:B0057973 ! YS049_HUMAN relationship: has_participant CCO:B0057976 ! PHF10_HUMAN relationship: has_participant CCO:B0057979 ! IASPP_HUMAN relationship: has_participant CCO:B0057980 ! CHUR_HUMAN relationship: has_participant CCO:B0057983 ! ZN296_HUMAN relationship: has_participant CCO:B0057984 ! GATD1_HUMAN relationship: has_participant CCO:B0057985 ! NAT14_HUMAN relationship: has_participant CCO:B0057987 ! ZN688_HUMAN relationship: has_participant CCO:B0057989 ! ZN480_HUMAN relationship: has_participant CCO:B0057990 ! LEO1_HUMAN relationship: has_participant CCO:B0057994 ! TWST2_HUMAN relationship: has_participant CCO:B0057995 ! TFB1M_HUMAN relationship: has_participant CCO:B0057998 ! Q8WVQ2_HUMAN relationship: has_participant CCO:B0057999 ! FOG2_HUMAN relationship: has_participant CCO:B0058003 ! Q8WWE6_HUMAN relationship: has_participant CCO:B0058008 ! MB3L1_HUMAN relationship: has_participant CCO:B0058011 ! 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ESR2_HUMAN relationship: has_participant CCO:B0058088 ! TAF4B_HUMAN relationship: has_participant CCO:B0058091 ! RREB1_HUMAN relationship: has_participant CCO:B0058092 ! DPF1_HUMAN relationship: has_participant CCO:B0058094 ! REQU_HUMAN relationship: has_participant CCO:B0058095 ! PROX1_HUMAN relationship: has_participant CCO:B0058096 ! EZH1_HUMAN relationship: has_participant CCO:B0058098 ! HXB13_HUMAN relationship: has_participant CCO:B0058099 ! JARD2_HUMAN relationship: has_participant CCO:B0058108 ! ATOH1_HUMAN relationship: has_participant CCO:B0058114 ! FUBP2_HUMAN relationship: has_participant CCO:B0058116 ! SNPC3_HUMAN relationship: has_participant CCO:B0058127 ! TCAL3_HUMAN relationship: has_participant CCO:B0058133 ! ZKSC4_HUMAN relationship: has_participant CCO:B0058140 ! LMBL2_HUMAN relationship: has_participant CCO:B0058143 ! MKL1_HUMAN relationship: has_participant CCO:B0058146 ! ISL2_HUMAN relationship: has_participant CCO:B0058151 ! FUBP1_HUMAN relationship: has_participant CCO:B0058152 ! Q96AG7_HUMAN relationship: has_participant CCO:B0058156 ! ECOP_HUMAN relationship: has_participant CCO:B0058161 ! CR3L1_HUMAN relationship: has_participant CCO:B0058162 ! PF21A_HUMAN relationship: has_participant CCO:B0058163 ! Q96BH8_HUMAN relationship: has_participant CCO:B0058167 ! TAD1L_HUMAN relationship: has_participant CCO:B0058170 ! ZN669_HUMAN relationship: has_participant CCO:B0058171 ! ZN775_HUMAN relationship: has_participant CCO:B0058173 ! ZBTB9_HUMAN relationship: has_participant CCO:B0058175 ! ZN707_HUMAN relationship: has_participant CCO:B0058176 ! ZN524_HUMAN relationship: has_participant CCO:B0058178 ! Q96C84_HUMAN relationship: has_participant CCO:B0058183 ! EAF2_HUMAN relationship: has_participant CCO:B0058184 ! ZN653_HUMAN relationship: has_participant CCO:B0058185 ! ZN689_HUMAN relationship: has_participant CCO:B0058186 ! ZN501_HUMAN relationship: has_participant CCO:B0058187 ! Q96CY8_HUMAN relationship: has_participant CCO:B0058190 ! EID2B_HUMAN relationship: has_participant CCO:B0058198 ! ZBT10_HUMAN relationship: has_participant CCO:B0058203 ! ELP4_HUMAN relationship: has_participant CCO:B0058204 ! SIRT1_HUMAN relationship: has_participant CCO:B0058205 ! ZN837_HUMAN relationship: has_participant CCO:B0058206 ! TCAL4_HUMAN relationship: has_participant CCO:B0058207 ! F120B_HUMAN relationship: has_participant CCO:B0058208 ! SGF29_HUMAN relationship: has_participant CCO:B0058209 ! NRBF2_HUMAN relationship: has_participant CCO:B0058210 ! ZN503_HUMAN relationship: has_participant CCO:B0058212 ! Q96G73_HUMAN relationship: has_participant CCO:B0058214 ! ZN274_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN relationship: has_participant CCO:B0058216 ! ZN799_HUMAN relationship: has_participant CCO:B0058217 ! Q96GH8_HUMAN relationship: has_participant CCO:B0058218 ! Q96GL3_HUMAN relationship: has_participant CCO:B0058219 ! CDA7L_HUMAN relationship: has_participant CCO:B0058220 ! ZN486_HUMAN relationship: has_participant CCO:B0058223 ! HES6_HUMAN relationship: has_participant CCO:B0058224 ! FUBP3_HUMAN relationship: has_participant CCO:B0058225 ! ZN625_HUMAN relationship: has_participant CCO:B0058231 ! ZN414_HUMAN relationship: has_participant CCO:B0058232 ! RAX2_HUMAN relationship: has_participant CCO:B0058233 ! ZN496_HUMAN relationship: has_participant CCO:B0058234 ! PAWR_HUMAN relationship: has_participant CCO:B0058238 ! ZN594_HUMAN relationship: has_participant CCO:B0058239 ! ZN469_HUMAN relationship: has_participant CCO:B0058241 ! Q96JJ8_HUMAN relationship: has_participant CCO:B0058242 ! MAML3_HUMAN relationship: has_participant CCO:B0058243 ! ZN333_HUMAN relationship: has_participant CCO:B0058244 ! ZN462_HUMAN relationship: has_participant CCO:B0058246 ! LCOR_HUMAN relationship: has_participant CCO:B0058247 ! ZFP91_HUMAN relationship: has_participant CCO:B0058249 ! PGBD1_HUMAN relationship: has_participant CCO:B0058251 ! ZN668_HUMAN relationship: has_participant CCO:B0058252 ! ZBT45_HUMAN relationship: has_participant CCO:B0058253 ! Q96K65_HUMAN relationship: has_participant CCO:B0058254 ! ZN514_HUMAN relationship: has_participant CCO:B0058256 ! ZN521_HUMAN relationship: has_participant CCO:B0058260 ! Z512B_HUMAN relationship: has_participant CCO:B0058261 ! PKNX2_HUMAN relationship: has_participant CCO:B0058263 ! Q96KW0_HUMAN relationship: has_participant CCO:B0058265 ! KCNH8_HUMAN relationship: has_participant CCO:B0058266 ! NSD1_HUMAN relationship: has_participant CCO:B0058272 ! HSFY1_HUMAN relationship: has_participant CCO:B0058273 ! Q96LU8_HUMAN relationship: has_participant CCO:B0058274 ! Z354B_HUMAN relationship: has_participant CCO:B0058277 ! ZN323_HUMAN relationship: has_participant CCO:B0058278 ! ZN597_HUMAN relationship: has_participant CCO:B0058283 ! DMRTB_HUMAN relationship: has_participant CCO:B0058285 ! Q96MC1_HUMAN relationship: has_participant CCO:B0058287 ! ZN512_HUMAN relationship: has_participant CCO:B0058289 ! Q96ML5_HUMAN relationship: has_participant CCO:B0058290 ! Q96MM8_HUMAN relationship: has_participant CCO:B0058291 ! ZN488_HUMAN relationship: has_participant CCO:B0058292 ! ZN560_HUMAN relationship: has_participant CCO:B0058293 ! ZN778_HUMAN relationship: has_participant CCO:B0058296 ! ZNF48_HUMAN relationship: has_participant CCO:B0058298 ! ZN681_HUMAN relationship: has_participant CCO:B0058299 ! ZN578_HUMAN relationship: has_participant CCO:B0058301 ! ZN641_HUMAN relationship: has_participant CCO:B0058302 ! ZN396_HUMAN relationship: has_participant CCO:B0058303 ! ZN583_HUMAN relationship: has_participant CCO:B0058304 ! ZN558_HUMAN relationship: has_participant CCO:B0058306 ! ZN570_HUMAN relationship: has_participant CCO:B0058307 ! ZFP3_HUMAN relationship: has_participant CCO:B0058308 ! NDF6_HUMAN relationship: has_participant CCO:B0058309 ! ZN599_HUMAN relationship: has_participant CCO:B0058310 ! TOX2_HUMAN relationship: has_participant CCO:B0058314 ! DACH2_HUMAN relationship: has_participant CCO:B0058315 ! FOXN4_HUMAN relationship: has_participant CCO:B0058332 ! ZIM3_HUMAN relationship: has_participant CCO:B0058337 ! RBM14_HUMAN relationship: has_participant CCO:B0058338 ! Z385A_HUMAN relationship: has_participant CCO:B0058340 ! TREF1_HUMAN relationship: has_participant CCO:B0058342 ! ZN317_HUMAN relationship: has_participant CCO:B0058343 ! DUX5_HUMAN relationship: has_participant CCO:B0058344 ! DUX3_HUMAN relationship: has_participant CCO:B0058348 ! FMNL2_HUMAN relationship: has_participant CCO:B0058354 ! Q96QH7_HUMAN relationship: has_participant CCO:B0058355 ! Q96QI0_HUMAN relationship: has_participant CCO:B0058357 ! ARX_HUMAN relationship: has_participant CCO:B0058374 ! BTB14_HUMAN relationship: has_participant CCO:B0058375 ! PASK_HUMAN relationship: has_participant CCO:B0058376 ! NR1H4_HUMAN relationship: has_participant CCO:B0058380 ! FER3L_HUMAN relationship: has_participant CCO:B0058381 ! UIMC1_HUMAN relationship: has_participant CCO:B0058387 ! AXUD1_HUMAN relationship: has_participant CCO:B0058390 ! DMTA2_HUMAN relationship: has_participant CCO:B0058392 ! FIZ1_HUMAN relationship: has_participant CCO:B0058393 ! ZN587_HUMAN relationship: has_participant CCO:B0058394 ! ATOH8_HUMAN relationship: has_participant CCO:B0058395 ! ZN382_HUMAN relationship: has_participant CCO:B0058397 ! ZSC10_HUMAN relationship: has_participant CCO:B0058398 ! RSF1_HUMAN relationship: has_participant CCO:B0058403 ! MMS19_HUMAN relationship: has_participant CCO:B0058404 ! INSM2_HUMAN relationship: has_participant CCO:B0058405 ! Q96TB0_HUMAN relationship: has_participant CCO:B0058408 ! HTF4_HUMAN relationship: has_participant CCO:B0058411 ! Q99419_HUMAN relationship: has_participant CCO:B0058412 ! PHX2B_HUMAN relationship: has_participant CCO:B0058414 ! NOTC4_HUMAN relationship: has_participant CCO:B0058416 ! PFD5_HUMAN relationship: has_participant CCO:B0058419 ! EYA1_HUMAN relationship: has_participant CCO:B0058420 ! EYA3_HUMAN relationship: has_participant CCO:B0058425 ! T22D3_HUMAN relationship: has_participant CCO:B0058427 ! FEV_HUMAN relationship: has_participant CCO:B0058428 ! ZN238_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: has_participant CCO:B0058430 ! ELF4_HUMAN relationship: has_participant CCO:B0058431 ! KLF6_HUMAN relationship: has_participant CCO:B0058432 ! PHB2_HUMAN relationship: has_participant CCO:B0058437 ! ZN184_HUMAN relationship: has_participant CCO:B0058441 ! PITX2_HUMAN relationship: has_participant CCO:B0058446 ! SMAD5_HUMAN relationship: has_participant CCO:B0058449 ! LITAF_HUMAN relationship: has_participant CCO:B0058451 ! NPAS1_HUMAN relationship: has_participant CCO:B0058455 ! NKX31_HUMAN relationship: has_participant CCO:B0058456 ! PRRX2_HUMAN relationship: has_participant CCO:B0058459 ! ARI3A_HUMAN relationship: has_participant CCO:B0058460 ! SSX3_HUMAN relationship: has_participant CCO:B0058461 ! ASCL2_HUMAN relationship: has_participant CCO:B0058463 ! ATF6B_HUMAN relationship: has_participant CCO:B0058467 ! VGLL1_HUMAN relationship: has_participant CCO:B0058472 ! HOP_HUMAN relationship: has_participant CCO:B0058475 ! TCF25_HUMAN relationship: has_participant CCO:B0058476 ! Q9BQ85_HUMAN relationship: has_participant CCO:B0058477 ! TBL1Y_HUMAN relationship: has_participant CCO:B0058478 ! MIZF_HUMAN relationship: has_participant CCO:B0058481 ! MBB1A_HUMAN relationship: has_participant CCO:B0058483 ! COE4_HUMAN relationship: has_participant CCO:B0058485 ! ZN559_HUMAN relationship: has_participant CCO:B0058486 ! Q9BR93_HUMAN relationship: has_participant CCO:B0058487 ! Q9BR99_HUMAN relationship: has_participant CCO:B0058490 ! VPS25_HUMAN relationship: has_participant CCO:B0058492 ! ZN251_HUMAN relationship: has_participant CCO:B0058493 ! MESP1_HUMAN relationship: has_participant CCO:B0058495 ! ZKSC3_HUMAN relationship: has_participant CCO:B0058498 ! TCAL7_HUMAN relationship: has_participant CCO:B0058499 ! Q9BRW7_HUMAN relationship: has_participant CCO:B0058503 ! ZN649_HUMAN relationship: has_participant CCO:B0058504 ! ZN670_HUMAN relationship: has_participant CCO:B0058505 ! ZNF2_HUMAN relationship: has_participant CCO:B0058506 ! ZN577_HUMAN relationship: has_participant CCO:B0058507 ! PCGF1_HUMAN relationship: has_participant CCO:B0058508 ! Q9BSN8_HUMAN relationship: has_participant CCO:B0058511 ! THAP7_HUMAN relationship: has_participant CCO:B0058513 ! SOX7_HUMAN relationship: has_participant CCO:B0058514 ! MTA3_HUMAN relationship: has_participant CCO:B0058516 ! ZN692_HUMAN relationship: has_participant CCO:B0058520 ! ZSA5A_HUMAN relationship: has_participant CCO:B0058522 ! HNRL1_HUMAN relationship: has_participant CCO:B0058524 ! ZN426_HUMAN relationship: has_participant CCO:B0058526 ! ZN747_HUMAN relationship: has_participant CCO:B0058527 ! PHF20_HUMAN relationship: has_participant CCO:B0058528 ! Q9BVY9_HUMAN relationship: has_participant CCO:B0058529 ! MAD3_HUMAN relationship: has_participant CCO:B0058534 ! ZN416_HUMAN relationship: has_participant CCO:B0058536 ! CDCA7_HUMAN relationship: has_participant CCO:B0058541 ! SSBP3_HUMAN relationship: has_participant CCO:B0058542 ! SCRT1_HUMAN relationship: has_participant CCO:B0058543 ! GATA5_HUMAN relationship: has_participant CCO:B0058546 ! ZN471_HUMAN relationship: has_participant CCO:B0058547 ! SALL3_HUMAN relationship: has_participant CCO:B0058553 ! SPZ1_HUMAN relationship: has_participant CCO:B0058556 ! NARG1_HUMAN relationship: has_participant CCO:B0058557 ! KLF16_HUMAN relationship: has_participant CCO:B0058564 ! AN30A_HUMAN relationship: has_participant CCO:B0058568 ! ZN717_HUMAN relationship: has_participant CCO:B0058569 ! HDAC8_HUMAN relationship: has_participant CCO:B0058576 ! HES7_HUMAN relationship: has_participant CCO:B0058579 ! IKBZ_HUMAN relationship: has_participant CCO:B0058580 ! ZN341_HUMAN relationship: has_participant CCO:B0058582 ! PBX4_HUMAN relationship: has_participant CCO:B0058585 ! BACH2_HUMAN relationship: has_participant CCO:B0058589 ! Q9BZ69_HUMAN relationship: has_participant CCO:B0058592 ! NSD3_HUMAN relationship: has_participant CCO:B0058596 ! Q9BZD1_HUMAN relationship: has_participant CCO:B0058597 ! BARH1_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN relationship: has_participant CCO:B0058607 ! Q9BZT2_HUMAN relationship: has_participant CCO:B0058608 ! PO5L3_HUMAN relationship: has_participant CCO:B0058609 ! PO5L4_HUMAN relationship: has_participant CCO:B0058615 ! ZFHX2_HUMAN relationship: has_participant CCO:B0058616 ! Z518B_HUMAN relationship: has_participant CCO:B0058617 ! ASXL3_HUMAN relationship: has_participant CCO:B0058618 ! ZN436_HUMAN relationship: has_participant CCO:B0058619 ! ZN407_HUMAN relationship: has_participant CCO:B0058621 ! BHLH3_HUMAN relationship: has_participant CCO:B0058622 ! BC11B_HUMAN relationship: has_participant CCO:B0058634 ! REXO4_HUMAN relationship: has_participant CCO:B0058635 ! SLIRP_HUMAN relationship: has_participant CCO:B0058637 ! PEG3_HUMAN relationship: has_participant CCO:B0058638 ! WWTR1_HUMAN relationship: has_participant CCO:B0058639 ! PRD14_HUMAN relationship: has_participant CCO:B0058641 ! ZN350_HUMAN relationship: has_participant CCO:B0058645 ! HXD1_HUMAN relationship: has_participant CCO:B0058650 ! SP130_HUMAN relationship: has_participant CCO:B0058651 ! BRD8_HUMAN relationship: has_participant CCO:B0058654 ! ZN700_HUMAN relationship: has_participant CCO:B0058659 ! GZF1_HUMAN relationship: has_participant CCO:B0058660 ! ALX4_HUMAN relationship: has_participant CCO:B0058661 ! CSRN2_HUMAN relationship: has_participant CCO:B0058664 ! Q9H1C9_HUMAN relationship: has_participant CCO:B0058676 ! KCNH6_HUMAN relationship: has_participant CCO:B0058680 ! LHX5_HUMAN relationship: has_participant CCO:B0058688 ! ADNP_HUMAN relationship: has_participant CCO:B0058690 ! MIXL1_HUMAN relationship: has_participant CCO:B0058702 ! TCAL2_HUMAN relationship: has_participant CCO:B0058703 ! Q9H3I5_HUMAN relationship: has_participant CCO:B0058707 ! NELFA_HUMAN relationship: has_participant CCO:B0058709 ! JHD3C_HUMAN relationship: has_participant CCO:B0058714 ! Q9H4A8_HUMAN relationship: has_participant CCO:B0058718 ! PRD13_HUMAN relationship: has_participant CCO:B0058719 ! PRD12_HUMAN relationship: has_participant CCO:B0058720 ! COE3_HUMAN relationship: has_participant CCO:B0058721 ! ZN335_HUMAN relationship: has_participant CCO:B0058722 ! ESF1_HUMAN relationship: has_participant CCO:B0058723 ! ZN644_HUMAN relationship: has_participant CCO:B0058725 ! ZN768_HUMAN relationship: has_participant CCO:B0058726 ! Q9H5I4_HUMAN relationship: has_participant CCO:B0058727 ! ZBTB3_HUMAN relationship: has_participant CCO:B0058728 ! TFB2M_HUMAN relationship: has_participant CCO:B0058729 ! IKZF5_HUMAN relationship: has_participant CCO:B0058730 ! ZN576_HUMAN relationship: has_participant CCO:B0058735 ! Q9H6M4_HUMAN relationship: has_participant CCO:B0058736 ! NO66_HUMAN relationship: has_participant CCO:B0058737 ! ZN552_HUMAN relationship: has_participant CCO:B0058740 ! Q9H7I9_HUMAN relationship: has_participant CCO:B0058744 ! ZN442_HUMAN relationship: has_participant CCO:B0058745 ! ZN665_HUMAN relationship: has_participant CCO:B0058746 ! ZN703_HUMAN relationship: has_participant CCO:B0058747 ! ZN696_HUMAN relationship: has_participant CCO:B0058748 ! MYST1_HUMAN relationship: has_participant CCO:B0058750 ! ZN395_HUMAN relationship: has_participant CCO:B0058751 ! Q9H8R0_HUMAN relationship: has_participant CCO:B0058752 ! Q9H942_HUMAN relationship: has_participant CCO:B0058753 ! ZN702_HUMAN relationship: has_participant CCO:B0058754 ! ZN408_HUMAN relationship: has_participant CCO:B0058756 ! NANOG_HUMAN relationship: has_participant CCO:B0058757 ! ELP3_HUMAN relationship: has_participant CCO:B0058758 ! LN28A_HUMAN relationship: has_participant CCO:B0058761 ! ZN556_HUMAN relationship: has_participant CCO:B0058763 ! SP30L_HUMAN relationship: has_participant CCO:B0058764 ! COE2_HUMAN relationship: has_participant CCO:B0058765 ! MLXIP_HUMAN relationship: has_participant CCO:B0058771 ! BRF2_HUMAN relationship: has_participant CCO:B0058772 ! PRD16_HUMAN relationship: has_participant CCO:B0058774 ! SEBOX_HUMAN relationship: has_participant CCO:B0058777 ! SP110_HUMAN relationship: has_participant CCO:B0058778 ! ELL3_HUMAN relationship: has_participant CCO:B0058782 ! PATZ1_HUMAN relationship: has_participant CCO:B0058789 ! Q9HBR4_HUMAN relationship: has_participant CCO:B0058790 ! ZN287_HUMAN relationship: has_participant CCO:B0058791 ! Z286A_HUMAN relationship: has_participant CCO:B0058792 ! BARX1_HUMAN relationship: has_participant CCO:B0058796 ! GPBL1_HUMAN relationship: has_participant CCO:B0058797 ! CBX8_HUMAN relationship: has_participant CCO:B0058799 ! ZBT20_HUMAN relationship: has_participant CCO:B0058801 ! HES4_HUMAN relationship: has_participant CCO:B0058802 ! NCOA5_HUMAN relationship: has_participant CCO:B0058803 ! ZN532_HUMAN relationship: has_participant CCO:B0058806 ! ZN160_HUMAN relationship: has_participant CCO:B0058809 ! ZBT26_HUMAN relationship: has_participant CCO:B0058811 ! ZFP14_HUMAN relationship: has_participant CCO:B0058819 ! PREB_HUMAN relationship: has_participant CCO:B0058820 ! ZN304_HUMAN relationship: has_participant CCO:B0058821 ! Q9HCY4_HUMAN relationship: has_participant CCO:B0058822 ! ZN334_HUMAN relationship: has_participant CCO:B0058823 ! SRA1_HUMAN relationship: has_participant CCO:B0058827 ! Q9HD74_HUMAN relationship: has_participant CCO:B0058828 ! NDF4_HUMAN relationship: has_participant CCO:B0058830 ! HMX1_HUMAN relationship: has_participant CCO:B0058834 ! GCM1_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN relationship: has_participant CCO:B0058843 ! ENY2_HUMAN relationship: has_participant CCO:B0058847 ! MYNN_HUMAN relationship: has_participant CCO:B0058848 ! SIX2_HUMAN relationship: has_participant CCO:B0058855 ! PNRC2_HUMAN relationship: has_participant CCO:B0058857 ! SCRT2_HUMAN relationship: has_participant CCO:B0058860 ! ASCL3_HUMAN relationship: has_participant CCO:B0058863 ! LHX9_HUMAN relationship: has_participant CCO:B0058865 ! HEYL_HUMAN relationship: has_participant CCO:B0058868 ! DMRT3_HUMAN relationship: has_participant CCO:B0058870 ! Q9NQR6_HUMAN relationship: has_participant CCO:B0058873 ! PRD10_HUMAN relationship: has_participant CCO:B0058874 ! PRDM9_HUMAN relationship: has_participant CCO:B0058875 ! PRDM8_HUMAN relationship: has_participant CCO:B0058876 ! PRDM7_HUMAN relationship: has_participant CCO:B0058878 ! PRDM6_HUMAN relationship: has_participant CCO:B0058879 ! PRDM5_HUMAN relationship: has_participant CCO:B0058880 ! ZN331_HUMAN relationship: has_participant CCO:B0058881 ! ZNF71_HUMAN relationship: has_participant CCO:B0058882 ! ZN302_HUMAN relationship: has_participant CCO:B0058886 ! ASH1L_HUMAN relationship: has_participant CCO:B0058887 ! BATF3_HUMAN relationship: has_participant CCO:B0058890 ! S2A4R_HUMAN relationship: has_participant CCO:B0058895 ! SIRT7_HUMAN relationship: has_participant CCO:B0058898 ! TSH2_HUMAN relationship: has_participant CCO:B0058900 ! TULP4_HUMAN relationship: has_participant CCO:B0058901 ! BAZ1A_HUMAN relationship: has_participant CCO:B0058908 ! KCNH7_HUMAN relationship: has_participant CCO:B0058914 ! SALL1_HUMAN relationship: has_participant CCO:B0058917 ! ZN275_HUMAN relationship: has_participant CCO:B0058920 ! BRWD1_HUMAN relationship: has_participant CCO:B0058921 ! ZN834_HUMAN relationship: has_participant CCO:B0058924 ! SIRT3_HUMAN relationship: has_participant CCO:B0058926 ! ZFP57_HUMAN relationship: has_participant CCO:B0058929 ! ZN701_HUMAN relationship: has_participant CCO:B0058932 ! ASF1B_HUMAN relationship: has_participant CCO:B0058934 ! RNF12_HUMAN relationship: has_participant CCO:B0058935 ! ZN358_HUMAN relationship: has_participant CCO:B0058936 ! IFT57_HUMAN relationship: has_participant CCO:B0058937 ! Q9NWF0_HUMAN relationship: has_participant CCO:B0058938 ! SLTM_HUMAN relationship: has_participant CCO:B0058941 ! HIF1N_HUMAN relationship: has_participant CCO:B0058947 ! SOLH2_HUMAN relationship: has_participant CCO:B0058950 ! ZN434_HUMAN relationship: has_participant CCO:B0058951 ! SIRT5_HUMAN relationship: has_participant CCO:B0058956 ! ZN586_HUMAN relationship: has_participant CCO:B0058958 ! BARH2_HUMAN relationship: has_participant CCO:B0058962 ! BCLF1_HUMAN relationship: has_participant CCO:B0058973 ! ZN226_HUMAN relationship: has_participant CCO:B0058974 ! RRN3_HUMAN relationship: has_participant CCO:B0058985 ! RBAK_HUMAN relationship: has_participant CCO:B0058991 ! EHF_HUMAN relationship: has_participant CCO:B0058997 ! GRHL1_HUMAN relationship: has_participant CCO:B0058998 ! TF2L1_HUMAN relationship: has_participant CCO:B0058999 ! UBIP1_HUMAN relationship: has_participant CCO:B0059004 ! ZN224_HUMAN relationship: has_participant CCO:B0059013 ! VSX1_HUMAN relationship: has_participant CCO:B0059021 ! ZIM2_HUMAN relationship: has_participant CCO:B0059025 ! TAP26_HUMAN relationship: has_participant CCO:B0059030 ! ZN167_HUMAN relationship: has_participant CCO:B0059034 ! CXXC1_HUMAN relationship: has_participant CCO:B0059042 ! Q9P1T1_HUMAN relationship: has_participant CCO:B0059043 ! MDFIC_HUMAN relationship: has_participant CCO:B0059046 ! ZBTB4_HUMAN relationship: has_participant CCO:B0059049 ! POGK_HUMAN relationship: has_participant CCO:B0059052 ! ZFAT_HUMAN relationship: has_participant CCO:B0059053 ! ZN492_HUMAN relationship: has_participant CCO:B0059056 ! CHD7_HUMAN relationship: has_participant CCO:B0059057 ! ZN319_HUMAN relationship: has_participant CCO:B0059058 ! RCOR3_HUMAN relationship: has_participant CCO:B0059063 ! ZN219_HUMAN relationship: has_participant CCO:B0059065 ! MBD2_HUMAN relationship: has_participant CCO:B0059067 ! HSFX1_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN relationship: has_participant CCO:B0059073 ! RBPJL_HUMAN relationship: has_participant CCO:B0059081 ! HEY2_HUMAN relationship: has_participant CCO:B0059083 ! RNF14_HUMAN relationship: has_participant CCO:B0059088 ! ZMYM2_HUMAN relationship: has_participant CCO:B0059089 ! HESX1_HUMAN relationship: has_participant CCO:B0059090 ! DUX4_HUMAN relationship: has_participant CCO:B0059093 ! Q9UC05_HUMAN relationship: has_participant CCO:B0059094 ! ZNF70_HUMAN relationship: has_participant CCO:B0059095 ! ZNF69_HUMAN relationship: has_participant CCO:B0059096 ! Q9UCY6_HUMAN relationship: has_participant CCO:B0059097 ! Q9UD04_HUMAN relationship: has_participant CCO:B0059098 ! NKX12_HUMAN relationship: has_participant CCO:B0059104 ! ZN212_HUMAN relationship: has_participant CCO:B0059105 ! ZN282_HUMAN relationship: has_participant CCO:B0059109 ! ZN629_HUMAN relationship: has_participant CCO:B0059114 ! ZBT47_HUMAN relationship: has_participant CCO:B0059115 ! Q9UFT8_HUMAN relationship: has_participant CCO:B0059117 ! CGBP1_HUMAN relationship: has_participant CCO:B0059124 ! JAD1B_HUMAN relationship: has_participant CCO:B0059126 ! TCF20_HUMAN relationship: has_participant CCO:B0059127 ! HM2L1_HUMAN relationship: has_participant CCO:B0059130 ! MLX_HUMAN relationship: has_participant CCO:B0059133 ! AFF4_HUMAN relationship: has_participant CCO:B0059138 ! TRPS1_HUMAN relationship: has_participant CCO:B0059148 ! S30BP_HUMAN relationship: has_participant CCO:B0059151 ! PUF60_HUMAN relationship: has_participant CCO:B0059156 ! ZN639_HUMAN relationship: has_participant CCO:B0059158 ! ZN230_HUMAN relationship: has_participant CCO:B0059159 ! BAZ2B_HUMAN relationship: has_participant CCO:B0059160 ! BAZ2A_HUMAN relationship: has_participant CCO:B0059161 ! BAZ1B_HUMAN relationship: has_participant CCO:B0059162 ! KLF15_HUMAN relationship: has_participant CCO:B0059163 ! ZN107_HUMAN relationship: has_participant CCO:B0059164 ! SIX4_HUMAN relationship: has_participant CCO:B0059166 ! VAX2_HUMAN relationship: has_participant CCO:B0059172 ! ZN643_HUMAN relationship: has_participant CCO:B0059173 ! ZN391_HUMAN relationship: has_participant CCO:B0059174 ! SALL4_HUMAN relationship: has_participant CCO:B0059175 ! LEF1_HUMAN relationship: has_participant CCO:B0059176 ! ZF112_HUMAN relationship: has_participant CCO:B0059178 ! ZN229_HUMAN relationship: has_participant CCO:B0059179 ! ZN180_HUMAN relationship: has_participant CCO:B0059180 ! SRTD3_HUMAN relationship: has_participant CCO:B0059183 ! ZN225_HUMAN relationship: has_participant CCO:B0059184 ! ZN223_HUMAN relationship: has_participant CCO:B0059185 ! ZN222_HUMAN relationship: has_participant CCO:B0059186 ! ZN221_HUMAN relationship: has_participant CCO:B0059191 ! GMEB2_HUMAN relationship: has_participant CCO:B0059194 ! RCOR1_HUMAN relationship: has_participant CCO:B0059197 ! PRDM4_HUMAN relationship: has_participant CCO:B0059203 ! ACAD8_HUMAN relationship: has_participant CCO:B0059208 ! ELF5_HUMAN relationship: has_participant CCO:B0059213 ! TBX21_HUMAN relationship: has_participant CCO:B0059216 ! ZN236_HUMAN relationship: has_participant CCO:B0059217 ! TCFL5_HUMAN relationship: has_participant CCO:B0059218 ! ZN215_HUMAN relationship: has_participant CCO:B0059219 ! ZN214_HUMAN relationship: has_participant CCO:B0059222 ! ZN777_HUMAN relationship: has_participant CCO:B0059223 ! KCNH3_HUMAN relationship: has_participant CCO:B0059226 ! MKL2_HUMAN relationship: has_participant CCO:B0059227 ! ZMIZ1_HUMAN relationship: has_participant CCO:B0059229 ! ZN490_HUMAN relationship: has_participant CCO:B0059230 ! YETS2_HUMAN relationship: has_participant CCO:B0059235 ! ABT1_HUMAN relationship: has_participant CCO:B0059242 ! PHTF1_HUMAN relationship: has_participant CCO:B0059246 ! SCML1_HUMAN relationship: has_participant CCO:B0059247 ! SOX13_HUMAN relationship: has_participant CCO:B0059253 ! TF2AY_HUMAN relationship: has_participant CCO:B0059256 ! TTF2_HUMAN relationship: has_participant CCO:B0059257 ! ZN232_HUMAN relationship: has_participant CCO:B0059261 ! LHX61_HUMAN relationship: has_participant CCO:B0059267 ! ZN409_HUMAN relationship: has_participant CCO:B0059270 ! SATB2_HUMAN relationship: has_participant CCO:B0059273 ! KCNH4_HUMAN relationship: has_participant CCO:B0059277 ! CTND2_HUMAN relationship: has_participant CCO:B0059279 ! Q9UQD2_HUMAN relationship: has_participant CCO:B0059284 ! SCML2_HUMAN relationship: has_participant CCO:B0059285 ! ZN148_HUMAN relationship: has_participant CCO:B0059300 ! ZN652_HUMAN relationship: has_participant CCO:B0059304 ! ZFP30_HUMAN relationship: has_participant CCO:B0059305 ! SBNO2_HUMAN relationship: has_participant CCO:B0059306 ! ZN510_HUMAN relationship: has_participant CCO:B0059309 ! ZBTB1_HUMAN relationship: has_participant CCO:B0059310 ! ZKSC5_HUMAN relationship: has_participant CCO:B0059311 ! ZN835_HUMAN relationship: has_participant CCO:B0059312 ! ZN256_HUMAN relationship: has_participant CCO:B0059313 ! ZN257_HUMAN relationship: has_participant CCO:B0059319 ! RX_HUMAN relationship: has_participant CCO:B0059320 ! TR150_HUMAN relationship: has_participant CCO:B0059321 ! ZN281_HUMAN relationship: has_participant CCO:B0059324 ! ZBT32_HUMAN relationship: has_participant CCO:B0059326 ! KLF13_HUMAN relationship: has_participant CCO:B0059329 ! ZBT12_HUMAN relationship: has_participant CCO:B0059340 ! ZN337_HUMAN relationship: has_participant CCO:B0059348 ! ZN711_HUMAN relationship: has_participant CCO:B0059350 ! NR2E1_HUMAN relationship: has_participant CCO:B0059351 ! SALL2_HUMAN relationship: has_participant CCO:B0059352 ! LMBL1_HUMAN relationship: has_participant CCO:B0059354 ! Q9Y4A3_HUMAN relationship: has_participant CCO:B0059355 ! NF2L3_HUMAN relationship: has_participant CCO:B0059357 ! JHD2A_HUMAN relationship: has_participant CCO:B0059366 ! KLF12_HUMAN relationship: has_participant CCO:B0059367 ! Q9Y4Y3_HUMAN relationship: has_participant CCO:B0059368 ! HES2_HUMAN relationship: has_participant CCO:B0059375 ! ZSC21_HUMAN relationship: has_participant CCO:B0059376 ! GCFC_HUMAN relationship: has_participant CCO:B0059378 ! HEY1_HUMAN relationship: has_participant CCO:B0059383 ! DMRT2_HUMAN relationship: has_participant CCO:B0059384 ! DMRT1_HUMAN relationship: has_participant CCO:B0059388 ! KLF2_HUMAN relationship: has_participant CCO:B0059391 ! NR2E3_HUMAN relationship: has_participant CCO:B0059395 ! ETV7_HUMAN relationship: has_participant CCO:B0059401 ! GMEB1_HUMAN relationship: has_participant CCO:B0059404 ! SIRT4_HUMAN relationship: has_participant CCO:B0059415 ! Z780B_HUMAN relationship: has_participant CCO:B0059420 ! CMTA1_HUMAN relationship: has_participant CCO:B0061983 ! RFX6_HUMAN [Term] id: CCO:P0000656 name: regulation of transcription from RNA polymerase I promoter namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter." [GOC:go_curators] synonym: "regulation of transcription from Pol I promoter" EXACT [] xref: GO:0006356 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: has_participant CCO:B0055088 ! UBF1_HUMAN relationship: has_participant CCO:B0055511 ! RPAB4_HUMAN relationship: has_participant CCO:B0055622 ! RPAB5_HUMAN relationship: has_participant CCO:B0055678 ! TFAM_HUMAN [Term] id: CCO:P0000657 name: regulation of transcription from RNA polymerase II promoter namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators] synonym: "regulation of transcription from Pol II promoter" EXACT [] xref: GO:0006357 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001431 ! SUPT3_HUMAN relationship: has_participant CCO:B0001433 ! TAD3L_HUMAN relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001522 ! FOSL1_HUMAN relationship: has_participant CCO:B0001530 ! JUNB_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001642 ! ERF_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001770 ! NFYC_HUMAN relationship: has_participant CCO:B0001776 ! TFDP1_HUMAN relationship: has_participant CCO:B0001959 ! TAF1L_HUMAN relationship: has_participant CCO:B0002022 ! NGN1_HUMAN relationship: has_participant CCO:B0002063 ! UHRF1_HUMAN relationship: has_participant CCO:B0002084 ! RBBP8_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0002098 ! HTAI2_HUMAN relationship: has_participant CCO:B0002107 ! FANCJ_HUMAN relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN relationship: has_participant CCO:B0005342 ! DEK_HUMAN relationship: has_participant CCO:B0005377 ! AP2C_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005398 ! ELP1_HUMAN relationship: has_participant CCO:B0005400 ! BRD7_HUMAN relationship: has_participant CCO:B0005414 ! SMCA4_HUMAN relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005419 ! SMRD2_HUMAN relationship: has_participant CCO:B0005485 ! SP1_HUMAN relationship: has_participant CCO:B0005575 ! MED26_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0005640 ! AP2A_HUMAN relationship: has_participant CCO:B0005647 ! GCNL2_HUMAN relationship: has_participant CCO:B0005667 ! ELOC_HUMAN relationship: has_participant CCO:B0005680 ! AP2B_HUMAN relationship: has_participant CCO:B0005780 ! MED27_HUMAN relationship: has_participant CCO:B0005781 ! MED20_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005793 ! MED23_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005878 ! GABPA_HUMAN relationship: has_participant CCO:B0005925 ! SMCA2_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0006011 ! TYY1_HUMAN relationship: has_participant CCO:B0006049 ! PO2F3_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006113 ! SAP18_HUMAN relationship: has_participant CCO:B0006154 ! PROF1_HUMAN relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN relationship: has_participant CCO:B0014838 ! SPT6H_HUMAN relationship: has_participant CCO:B0015238 ! FOXK2_HUMAN relationship: has_participant CCO:B0015239 ! FOXK1_HUMAN relationship: has_participant CCO:B0015243 ! TCEA3_HUMAN relationship: has_participant CCO:B0016028 ! HIRA_HUMAN relationship: has_participant CCO:B0018668 ! TBX1_HUMAN relationship: has_participant CCO:B0018676 ! TBX10_HUMAN relationship: has_participant CCO:B0018951 ! ATF6A_HUMAN relationship: has_participant CCO:B0018982 ! SNF8_HUMAN relationship: has_participant CCO:B0019606 ! BUD31_HUMAN relationship: has_participant CCO:B0020218 ! CSEN_HUMAN relationship: has_participant CCO:B0020253 ! SOX12_HUMAN relationship: has_participant CCO:B0020259 ! SOX18_HUMAN relationship: has_participant CCO:B0020263 ! SOX21_HUMAN relationship: has_participant CCO:B0020283 ! SOX15_HUMAN relationship: has_participant CCO:B0021030 ! CHD1_HUMAN relationship: has_participant CCO:B0021032 ! CHD2_HUMAN relationship: has_participant CCO:B0021706 ! CITE1_HUMAN relationship: has_participant CCO:B0022226 ! ID4_HUMAN relationship: has_participant CCO:B0023422 ! STAT2_HUMAN relationship: has_participant CCO:B0023501 ! TAF6L_HUMAN relationship: has_participant CCO:B0024875 ! COT2_HUMAN relationship: has_participant CCO:B0026258 ! TCF19_HUMAN relationship: has_participant CCO:B0026531 ! CLOCK_HUMAN relationship: has_participant CCO:B0028029 ! GO45_HUMAN relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0029685 ! STAT6_HUMAN relationship: has_participant CCO:B0032261 ! TEAD3_HUMAN relationship: has_participant CCO:B0032520 ! LRRF1_HUMAN relationship: has_participant CCO:B0033778 ! SODM_HUMAN relationship: has_participant CCO:B0036469 ! HCFC2_HUMAN relationship: has_participant CCO:B0036813 ! HXC5_HUMAN relationship: has_participant CCO:B0036818 ! HXC6_HUMAN relationship: has_participant CCO:B0036823 ! MNX1_HUMAN relationship: has_participant CCO:B0036939 ! HNF4G_HUMAN relationship: has_participant CCO:B0038370 ! IKZF3_HUMAN relationship: has_participant CCO:B0040022 ! JMY_HUMAN relationship: has_participant CCO:B0040683 ! GABP1_HUMAN relationship: has_participant CCO:B0040687 ! CUX1_HUMAN relationship: has_participant CCO:B0048571 ! SNW1_HUMAN relationship: has_participant CCO:B0048582 ! ELP2_HUMAN relationship: has_participant CCO:B0048650 ! PO4F1_HUMAN relationship: has_participant CCO:B0048651 ! PO4F3_HUMAN relationship: has_participant CCO:B0048655 ! PO3F2_HUMAN relationship: has_participant CCO:B0048676 ! TCP4_HUMAN relationship: has_participant CCO:B0049069 ! ONEC3_HUMAN relationship: has_participant CCO:B0049848 ! RNF4_HUMAN relationship: has_participant CCO:B0049929 ! SRBP1_HUMAN relationship: has_participant CCO:B0049934 ! SRBP2_HUMAN relationship: has_participant CCO:B0050294 ! HMGB2_HUMAN relationship: has_participant CCO:B0051010 ! SPT4H_HUMAN relationship: has_participant CCO:B0054431 ! FOXN1_HUMAN relationship: has_participant CCO:B0054439 ! GSC2_HUMAN relationship: has_participant CCO:B0054514 ! HTSF1_HUMAN relationship: has_participant CCO:B0054538 ! SMCA5_HUMAN relationship: has_participant CCO:B0054579 ! Z354A_HUMAN relationship: has_participant CCO:B0054580 ! TBX19_HUMAN relationship: has_participant CCO:B0054660 ! CREG1_HUMAN relationship: has_participant CCO:B0054673 ! KLF7_HUMAN relationship: has_participant CCO:B0054691 ! CIAO1_HUMAN relationship: has_participant CCO:B0054697 ! RMP_HUMAN relationship: has_participant CCO:B0054833 ! FOS_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN relationship: has_participant CCO:B0055012 ! MYF5_HUMAN relationship: has_participant CCO:B0055036 ! FOSL2_HUMAN relationship: has_participant CCO:B0055045 ! GATA1_HUMAN relationship: has_participant CCO:B0055089 ! JUND_HUMAN relationship: has_participant CCO:B0055153 ! TCEA1_HUMAN relationship: has_participant CCO:B0055156 ! MYF6_HUMAN relationship: has_participant CCO:B0055254 ! OTX1_HUMAN relationship: has_participant CCO:B0055255 ! OTX2_HUMAN relationship: has_participant CCO:B0055306 ! TCF7_HUMAN relationship: has_participant CCO:B0055309 ! ZNF76_HUMAN relationship: has_participant CCO:B0055317 ! ZEB1_HUMAN relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0055403 ! SOX9_HUMAN relationship: has_participant CCO:B0055499 ! ZN143_HUMAN relationship: has_participant CCO:B0055506 ! NKX25_HUMAN relationship: has_participant CCO:B0055535 ! PKNX1_HUMAN relationship: has_participant CCO:B0055547 ! SOX10_HUMAN relationship: has_participant CCO:B0055557 ! SOX8_HUMAN relationship: has_participant CCO:B0055684 ! TIAR_HUMAN relationship: has_participant CCO:B0055693 ! TFAP4_HUMAN relationship: has_participant CCO:B0055695 ! SPIB_HUMAN relationship: has_participant CCO:B0055704 ! SP2_HUMAN relationship: has_participant CCO:B0055709 ! SP4_HUMAN relationship: has_participant CCO:B0055722 ! PPARD_HUMAN relationship: has_participant CCO:B0055834 ! DBP_HUMAN relationship: has_participant CCO:B0055835 ! TEF_HUMAN relationship: has_participant CCO:B0055842 ! TFCP2_HUMAN relationship: has_participant CCO:B0055852 ! TCF15_HUMAN relationship: has_participant CCO:B0055859 ! NFAC3_HUMAN relationship: has_participant CCO:B0055892 ! STF1_HUMAN relationship: has_participant CCO:B0055905 ! TARB1_HUMAN relationship: has_participant CCO:B0055949 ! KLF9_HUMAN relationship: has_participant CCO:B0055958 ! VEZF1_HUMAN relationship: has_participant CCO:B0055974 ! ELOA1_HUMAN relationship: has_participant CCO:B0055989 ! HLTF_HUMAN relationship: has_participant CCO:B0056018 ! CHD4_HUMAN relationship: has_participant CCO:B0056022 ! MTF1_HUMAN relationship: has_participant CCO:B0056058 ! ANKR1_HUMAN relationship: has_participant CCO:B0056086 ! TRBP2_HUMAN relationship: has_participant CCO:B0056101 ! ELF2_HUMAN relationship: has_participant CCO:B0056111 ! NDF2_HUMAN relationship: has_participant CCO:B0056162 ! NFE2_HUMAN relationship: has_participant CCO:B0056169 ! NRF1_HUMAN relationship: has_participant CCO:B0056464 ! Q5JRI7_HUMAN relationship: has_participant CCO:B0056565 ! UTF1_HUMAN relationship: has_participant CCO:B0056941 ! SMRD3_HUMAN relationship: has_participant CCO:B0057042 ! SRCAP_HUMAN relationship: has_participant CCO:B0057138 ! ZN367_HUMAN relationship: has_participant CCO:B0057262 ! Q86VL0_HUMAN relationship: has_participant CCO:B0057515 ! TFSC1_HUMAN relationship: has_participant CCO:B0057926 ! SP7_HUMAN relationship: has_participant CCO:B0057999 ! FOG2_HUMAN relationship: has_participant CCO:B0058203 ! ELP4_HUMAN relationship: has_participant CCO:B0058223 ! HES6_HUMAN relationship: has_participant CCO:B0058408 ! HTF4_HUMAN relationship: has_participant CCO:B0058449 ! LITAF_HUMAN relationship: has_participant CCO:B0058513 ! SOX7_HUMAN relationship: has_participant CCO:B0058557 ! KLF16_HUMAN relationship: has_participant CCO:B0058595 ! ABCA2_HUMAN relationship: has_participant CCO:B0058651 ! BRD8_HUMAN relationship: has_participant CCO:B0058660 ! ALX4_HUMAN relationship: has_participant CCO:B0058757 ! ELP3_HUMAN relationship: has_participant CCO:B0058852 ! UBN1_HUMAN relationship: has_participant CCO:B0058860 ! ASCL3_HUMAN relationship: has_participant CCO:B0058992 ! SMAL1_HUMAN relationship: has_participant CCO:B0058998 ! TF2L1_HUMAN relationship: has_participant CCO:B0058999 ! UBIP1_HUMAN relationship: has_participant CCO:B0059083 ! RNF14_HUMAN relationship: has_participant CCO:B0059269 ! TRAK1_HUMAN relationship: has_participant CCO:B0059366 ! KLF12_HUMAN [Term] id: CCO:P0000658 name: regulation of transcription from RNA polymerase II promoter, global namespace: biological_process def: "Any process that modulates the frequency, rate or extent of global transcription from Pol II promoter." [GOC:go_curators] synonym: "global transcription regulation from Pol II promoter" EXACT [] synonym: "regulation of global transcription from Pol II promoter" EXACT [] xref: GO:0006358 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0049757 ! CNOT2_HUMAN [Term] id: CCO:P0000659 name: regulation of transcription from RNA polymerase III promoter namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA ploymerase III promoter." [GOC:go_curators] synonym: "regulation of transcription from Pol III promoter" EXACT [] xref: GO:0006359 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0006101 ! RPC6_HUMAN relationship: has_participant CCO:B0054428 ! RPC7_HUMAN relationship: has_participant CCO:B0055309 ! ZNF76_HUMAN relationship: has_participant CCO:B0055499 ! ZN143_HUMAN relationship: has_participant CCO:B0055997 ! ZN345_HUMAN relationship: has_participant CCO:B0058521 ! RPC3_HUMAN [Term] id: CCO:P0000660 name: regulation of translation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA." [GOC:isa_complete] subset: gosubset_prok synonym: "regulation of protein anabolism" EXACT [] synonym: "regulation of protein biosynthesis" EXACT [] synonym: "regulation of protein formation" EXACT [] synonym: "regulation of protein synthesis" EXACT [] xref: GO:0006417 xref: GO:0006445 is_a: CCO:P0001008 ! posttranscriptional regulation of gene expression is_a: CCO:P0001407 ! regulation of cellular biosynthetic process is_a: CCO:P0001572 ! regulation of cellular protein metabolic process relationship: has_participant CCO:B0001436 ! PR15A_HUMAN relationship: has_participant CCO:B0001501 ! K2C7_HUMAN relationship: has_participant CCO:B0001699 ! IF4G2_HUMAN relationship: has_participant CCO:B0001972 ! BOLL_HUMAN relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005674 ! E2AK1_HUMAN relationship: has_participant CCO:B0005988 ! ATX2_HUMAN relationship: has_participant CCO:B0006179 ! APLP1_HUMAN relationship: has_participant CCO:B0016186 ! IF4E_HUMAN relationship: has_participant CCO:B0016191 ! I4E1B_HUMAN relationship: has_participant CCO:B0016344 ! IF4G3_HUMAN relationship: has_participant CCO:B0024383 ! PUM2_HUMAN relationship: has_participant CCO:B0024392 ! PUM1_HUMAN relationship: has_participant CCO:B0026498 ! TISB_HUMAN relationship: has_participant CCO:B0029151 ! AMPM1_HUMAN relationship: has_participant CCO:B0041436 ! IF2A_HUMAN relationship: has_participant CCO:B0054154 ! MI4GD_HUMAN relationship: has_participant CCO:B0054319 ! IF2B3_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0054565 ! 4EBP3_HUMAN relationship: has_participant CCO:B0054567 ! IF4E2_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0055571 ! MTPN_HUMAN relationship: has_participant CCO:B0055596 ! NANO2_HUMAN relationship: has_participant CCO:B0055597 ! NANO3_HUMAN relationship: has_participant CCO:B0055658 ! HCC1_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN relationship: has_participant CCO:B0055928 ! 4EBP2_HUMAN relationship: has_participant CCO:B0056548 ! PR15B_HUMAN relationship: has_participant CCO:B0057184 ! CPEB2_HUMAN relationship: has_participant CCO:B0057481 ! IF4E3_HUMAN relationship: has_participant CCO:B0057591 ! NGDN_HUMAN relationship: has_participant CCO:B0058039 ! NANO1_HUMAN relationship: has_participant CCO:B0058073 ! GCN1L_HUMAN relationship: has_participant CCO:B0058111 ! DAZL_HUMAN relationship: has_participant CCO:B0058345 ! QKI_HUMAN relationship: has_participant CCO:B0058473 ! PAIP2_HUMAN relationship: has_participant CCO:B0058519 ! MKNK1_HUMAN relationship: has_participant CCO:B0058570 ! EIF2A_HUMAN relationship: has_participant CCO:B0058593 ! CPEB1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN relationship: has_participant CCO:B0058786 ! MKNK2_HUMAN relationship: has_participant CCO:B0059000 ! IF2B1_HUMAN relationship: has_participant CCO:B0059062 ! IMPCT_HUMAN relationship: has_participant CCO:B0059144 ! DDX25_HUMAN relationship: has_participant CCO:B0059154 ! EI2BD_HUMAN relationship: has_participant CCO:B0059410 ! IF2B2_HUMAN [Term] id: CCO:P0000661 name: regulation of translational initiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] subset: gosubset_prok xref: GO:0006446 is_a: CCO:P0000660 ! regulation of translation is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0001699 ! IF4G2_HUMAN relationship: has_participant CCO:B0005728 ! IF4A2_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0016057 ! I2C1_HUMAN relationship: has_participant CCO:B0016344 ! IF4G3_HUMAN relationship: has_participant CCO:B0019928 ! EIF1_HUMAN relationship: has_participant CCO:B0019930 ! EIF1B_HUMAN relationship: has_participant CCO:B0023063 ! IF2M_HUMAN relationship: has_participant CCO:B0026269 ! EIF3G_HUMAN relationship: has_participant CCO:B0026270 ! EIF3D_HUMAN relationship: has_participant CCO:B0026271 ! EIF3C_HUMAN relationship: has_participant CCO:B0026272 ! EIF3E_HUMAN relationship: has_participant CCO:B0026273 ! EIF3I_HUMAN relationship: has_participant CCO:B0026274 ! EIF3K_HUMAN relationship: has_participant CCO:B0026277 ! EIF3F_HUMAN relationship: has_participant CCO:B0026278 ! EIF3J_HUMAN relationship: has_participant CCO:B0050510 ! IF4B_HUMAN relationship: has_participant CCO:B0051549 ! IF5_HUMAN relationship: has_participant CCO:B0054433 ! EIF3H_HUMAN relationship: has_participant CCO:B0054581 ! IF2P_HUMAN relationship: has_participant CCO:B0055434 ! EI2BB_HUMAN relationship: has_participant CCO:B0055731 ! IF4G1_HUMAN relationship: has_participant CCO:B0055965 ! EIF3A_HUMAN relationship: has_participant CCO:B0056040 ! IF4H_HUMAN relationship: has_participant CCO:B0058058 ! DDX1_HUMAN relationship: has_participant CCO:B0058687 ! IF3M_HUMAN relationship: has_participant CCO:B0059059 ! E2AK4_HUMAN relationship: has_participant CCO:B0059170 ! TRM6_HUMAN [Term] id: CCO:P0000662 name: regulation of translational initiation by iron namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron." [GOC:jl] subset: gosubset_prok xref: GO:0006447 is_a: CCO:P0000661 ! regulation of translational initiation [Term] id: CCO:P0000663 name: regulation of translational elongation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational elongation." [GOC:go_curators] subset: gosubset_prok xref: GO:0006448 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0000664 name: regulation of translational termination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational termination." [GOC:go_curators] subset: gosubset_prok xref: GO:0006449 is_a: CCO:P0000660 ! regulation of translation is_a: CCO:P0002175 ! regulation of protein complex disassembly relationship: has_participant CCO:B0002024 ! RENT1_HUMAN relationship: has_participant CCO:B0026435 ! UK114_HUMAN relationship: has_participant CCO:B0040310 ! RF1M_HUMAN relationship: has_participant CCO:B0055619 ! ERF1_HUMAN [Term] id: CCO:P0000665 name: regulation of translational fidelity namespace: biological_process def: "Any process that modulates the ability of the translational apparatus to interpret the genetic code." [GOC:dph, GOC:tb] subset: gosubset_prok synonym: "regulation of translational accuracy" EXACT [] xref: GO:0000029 xref: GO:0006450 is_a: CCO:P0000660 ! regulation of translation relationship: has_participant CCO:B0054513 ! GATCL_HUMAN [Term] id: CCO:P0000666 name: translational readthrough namespace: biological_process def: "The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons." [GOC:jsg] subset: gosubset_prok synonym: "natural nonsense suppression" RELATED [] xref: GO:0006451 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0000667 name: translational frameshifting namespace: biological_process def: "A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon." [GOC:hjd, ISBN:0195094425] subset: gosubset_prok xref: GO:0006452 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0000668 name: regulation of amino acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of amino acid metabolism" EXACT [] xref: GO:0006521 is_a: CCO:P0001817 ! regulation of amine metabolic process relationship: has_participant CCO:B0054852 ! INS_HUMAN [Term] id: CCO:P0000669 name: regulation of sulfur utilization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sulfur utilization." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of sulphur utilization" EXACT [] xref: GO:0006792 is_a: CCO:P0002124 ! regulation of sulfur metabolic process [Term] id: CCO:P0000670 name: regulation of phosphorus utilization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phosphorus utilization." [GOC:go_curators] subset: gosubset_prok xref: GO:0006795 is_a: CCO:P0003053 ! regulation of phosphorus metabolic process [Term] id: CCO:P0000671 name: anti-apoptosis namespace: biological_process def: "A process which directly inhibits any of the steps required for cell death by apoptosis." [GOC:go_curators] synonym: "apoptosis inhibitor activity" RELATED [] xref: GO:0006916 is_a: CCO:P0002148 ! negative regulation of apoptosis relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001376 ! HDAC3_HUMAN relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001398 ! TRIA1_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001475 ! IL1A_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001479 ! ANXA1_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0001806 ! DHC24_HUMAN relationship: has_participant CCO:B0002098 ! HTAI2_HUMAN relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0002251 ! ATF5_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005446 ! AATF_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005484 ! HDAC1_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN relationship: has_participant CCO:B0005677 ! BNIP2_HUMAN relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0005822 ! HSP71_HUMAN relationship: has_participant CCO:B0005828 ! GRP75_HUMAN relationship: has_participant CCO:B0005842 ! HSPB1_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN relationship: has_participant CCO:B0005913 ! BRAF1_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0005950 ! BECN1_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0006145 ! GSTP1_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN relationship: has_participant CCO:B0015655 ! HIPK3_HUMAN relationship: has_participant CCO:B0015822 ! ANXA5_HUMAN relationship: has_participant CCO:B0015859 ! ANXA4_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0016881 ! FOXO1_HUMAN relationship: has_participant CCO:B0017123 ! PROK2_HUMAN relationship: has_participant CCO:B0018239 ! SYUA_HUMAN relationship: has_participant CCO:B0019428 ! CPIN1_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN relationship: has_participant CCO:B0036188 ! TCTP_HUMAN relationship: has_participant CCO:B0036431 ! SPHK2_HUMAN relationship: has_participant CCO:B0038965 ! CCL2_HUMAN relationship: has_participant CCO:B0039811 ! BIRC6_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN relationship: has_participant CCO:B0042870 ! EF1A2_HUMAN relationship: has_participant CCO:B0043436 ! PRIO_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0050340 ! CD40L_HUMAN relationship: has_participant CCO:B0054304 ! CBX4_HUMAN relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0054573 ! FAIM3_HUMAN relationship: has_participant CCO:B0054591 ! NOL3_HUMAN relationship: has_participant CCO:B0054621 ! O75353_HUMAN relationship: has_participant CCO:B0054632 ! NDK6_HUMAN relationship: has_participant CCO:B0054753 ! TFIP8_HUMAN relationship: has_participant CCO:B0054760 ! TNR6B_HUMAN relationship: has_participant CCO:B0054761 ! TIAF1_HUMAN relationship: has_participant CCO:B0054763 ! BAG4_HUMAN relationship: has_participant CCO:B0054768 ! VNN1_HUMAN relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0054796 ! BAG3_HUMAN relationship: has_participant CCO:B0054801 ! DDAH2_HUMAN relationship: has_participant CCO:B0054802 ! O95880_HUMAN relationship: has_participant CCO:B0054860 ! CRYAA_HUMAN relationship: has_participant CCO:B0054861 ! CRYAB_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0054896 ! PAI2_HUMAN relationship: has_participant CCO:B0054897 ! PERM_HUMAN relationship: has_participant CCO:B0054905 ! DPOLB_HUMAN relationship: has_participant CCO:B0054910 ! GPX1_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0054951 ! IFI6_HUMAN relationship: has_participant CCO:B0054980 ! CLUS_HUMAN relationship: has_participant CCO:B0055025 ! ENPL_HUMAN relationship: has_participant CCO:B0055053 ! PRLR_HUMAN relationship: has_participant CCO:B0055097 ! LOX12_HUMAN relationship: has_participant CCO:B0055101 ! SON_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0055114 ! CAP7_HUMAN relationship: has_participant CCO:B0055134 ! TNAP3_HUMAN relationship: has_participant CCO:B0055142 ! IL10_HUMAN relationship: has_participant CCO:B0055163 ! PAX7_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN relationship: has_participant CCO:B0055249 ! PRDX2_HUMAN relationship: has_participant CCO:B0055323 ! GDNF_HUMAN relationship: has_participant CCO:B0055379 ! IEX1_HUMAN relationship: has_participant CCO:B0055404 ! GSH1_HUMAN relationship: has_participant CCO:B0055546 ! NDK5_HUMAN relationship: has_participant CCO:B0055612 ! DAD1_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN relationship: has_participant CCO:B0055735 ! LGUL_HUMAN relationship: has_participant CCO:B0055785 ! MCL1_HUMAN relationship: has_participant CCO:B0055862 ! SEC20_HUMAN relationship: has_participant CCO:B0055870 ! BIRC1_HUMAN relationship: has_participant CCO:B0055883 ! Q13169_HUMAN relationship: has_participant CCO:B0055917 ! BIRC3_HUMAN relationship: has_participant CCO:B0056045 ! PEA15_HUMAN relationship: has_participant CCO:B0056148 ! B2LA1_HUMAN relationship: has_participant CCO:B0056955 ! GFRAL_HUMAN relationship: has_participant CCO:B0057266 ! TAXB1_HUMAN relationship: has_participant CCO:B0057344 ! HUNIN_HUMAN relationship: has_participant CCO:B0057464 ! SFRP1_HUMAN relationship: has_participant CCO:B0057559 ! TXND5_HUMAN relationship: has_participant CCO:B0058072 ! MY18A_HUMAN relationship: has_participant CCO:B0058107 ! SEM4D_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0058462 ! BAG1_HUMAN relationship: has_participant CCO:B0058480 ! SELS_HUMAN relationship: has_participant CCO:B0058535 ! FAIM2_HUMAN relationship: has_participant CCO:B0058603 ! Q9BZL0_HUMAN relationship: has_participant CCO:B0058612 ! API5_HUMAN relationship: has_participant CCO:B0058705 ! TXND1_HUMAN relationship: has_participant CCO:B0058871 ! AVEN_HUMAN relationship: has_participant CCO:B0059015 ! BFAR_HUMAN relationship: has_participant CCO:B0059054 ! PAK7_HUMAN relationship: has_participant CCO:B0059071 ! RBX2_HUMAN relationship: has_participant CCO:B0059079 ! TR10D_HUMAN relationship: has_participant CCO:B0059106 ! MALT1_HUMAN relationship: has_participant CCO:B0059107 ! CFDP1_HUMAN relationship: has_participant CCO:B0059333 ! SHLB1_HUMAN relationship: has_participant CCO:B0059387 ! TNR18_HUMAN [Term] id: CCO:P0000672 name: induction of apoptosis namespace: biological_process def: "A process that directly activates any of the steps required for cell death by apoptosis." [GOC:go_curators] synonym: "activation of apoptosis" EXACT [] synonym: "apoptosis activator activity" RELATED [] synonym: "apoptosis signaling" BROAD [] synonym: "commitment to apoptosis" EXACT [] synonym: "induction of apoptosis by p53" NARROW [] xref: GO:0006917 is_a: CCO:P0001050 ! induction of programmed cell death is_a: CCO:P0002147 ! positive regulation of apoptosis relationship: has_participant CCO:B0001371 ! LX15B_HUMAN relationship: has_participant CCO:B0001428 ! ERN1_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001619 ! DCC_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0001842 ! BMCC1_HUMAN relationship: has_participant CCO:B0001928 ! ERN2_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0002046 ! ASPP1_HUMAN relationship: has_participant CCO:B0002098 ! HTAI2_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0002231 ! PLAL1_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN relationship: has_participant CCO:B0005316 ! NDK3_HUMAN relationship: has_participant CCO:B0005407 ! HD_HUMAN relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0005768 ! RS3A_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0006003 ! BIM_HUMAN relationship: has_participant CCO:B0006014 ! ZN443_HUMAN relationship: has_participant CCO:B0006060 ! DAPK3_HUMAN relationship: has_participant CCO:B0006152 ! PDCD5_HUMAN relationship: has_participant CCO:B0006340 ! APR_HUMAN relationship: has_participant CCO:B0015966 ! IFNB_HUMAN relationship: has_participant CCO:B0015973 ! IFNA2_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0016798 ! PLAL2_HUMAN relationship: has_participant CCO:B0018770 ! M3K10_HUMAN relationship: has_participant CCO:B0021316 ! Q9C054_HUMAN relationship: has_participant CCO:B0021348 ! Q15959_HUMAN relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0023521 ! CD2_HUMAN relationship: has_participant CCO:B0025054 ! KPCE_HUMAN relationship: has_participant CCO:B0026248 ! ERCC2_HUMAN relationship: has_participant CCO:B0026744 ! B2L13_HUMAN relationship: has_participant CCO:B0028502 ! ERCC3_HUMAN relationship: has_participant CCO:B0029119 ! Q9UL32_HUMAN relationship: has_participant CCO:B0029122 ! BOK_HUMAN relationship: has_participant CCO:B0030171 ! TLR2_HUMAN relationship: has_participant CCO:B0036514 ! ST17A_HUMAN relationship: has_participant CCO:B0036523 ! ST17B_HUMAN relationship: has_participant CCO:B0036525 ! DAPK2_HUMAN relationship: has_participant CCO:B0036567 ! IF5A1_HUMAN relationship: has_participant CCO:B0040022 ! JMY_HUMAN relationship: has_participant CCO:B0040471 ! CASP4_HUMAN relationship: has_participant CCO:B0043604 ! DEDD_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0048975 ! TGM2_HUMAN relationship: has_participant CCO:B0050722 ! GCH1_HUMAN relationship: has_participant CCO:B0054298 ! HRK_HUMAN relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0054365 ! EI24_HUMAN relationship: has_participant CCO:B0054377 ! UN13B_HUMAN relationship: has_participant CCO:B0054423 ! SIVA_HUMAN relationship: has_participant CCO:B0054484 ! TNF12_HUMAN relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0054550 ! NUPR1_HUMAN relationship: has_participant CCO:B0054644 ! NDUS3_HUMAN relationship: has_participant CCO:B0054651 ! PRKRA_HUMAN relationship: has_participant CCO:B0054679 ! SPF30_HUMAN relationship: has_participant CCO:B0054825 ! LALBA_HUMAN relationship: has_participant CCO:B0054826 ! PLMN_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0054870 ! CO9_HUMAN relationship: has_participant CCO:B0054921 ! TNR16_HUMAN relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0055131 ! MAL_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN relationship: has_participant CCO:B0055244 ! TIA1_HUMAN relationship: has_participant CCO:B0055262 ! CD70_HUMAN relationship: has_participant CCO:B0055263 ! TNFL8_HUMAN relationship: has_participant CCO:B0055351 ! CASP3_HUMAN relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0055454 ! AP4A_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055531 ! CASP6_HUMAN relationship: has_participant CCO:B0055684 ! TIAR_HUMAN relationship: has_participant CCO:B0055696 ! CO4A3_HUMAN relationship: has_participant CCO:B0055780 ! TNR9_HUMAN relationship: has_participant CCO:B0055862 ! SEC20_HUMAN relationship: has_participant CCO:B0055866 ! BAK2_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0055925 ! SERC3_HUMAN relationship: has_participant CCO:B0056712 ! NAIF1_HUMAN relationship: has_participant CCO:B0056967 ! Q6W3F3_HUMAN relationship: has_participant CCO:B0057517 ! PDCD7_HUMAN relationship: has_participant CCO:B0057558 ! PCSK9_HUMAN relationship: has_participant CCO:B0058092 ! DPF1_HUMAN relationship: has_participant CCO:B0058094 ! REQU_HUMAN relationship: has_participant CCO:B0058106 ! CASPA_HUMAN relationship: has_participant CCO:B0058121 ! TNR25_HUMAN relationship: has_participant CCO:B0058155 ! CIDEC_HUMAN relationship: has_participant CCO:B0058311 ! AIFM3_HUMAN relationship: has_participant CCO:B0058316 ! NALP3_HUMAN relationship: has_participant CCO:B0058335 ! NOX5_HUMAN relationship: has_participant CCO:B0058389 ! PKHF1_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: has_participant CCO:B0058494 ! AIFM2_HUMAN relationship: has_participant CCO:B0058532 ! TRAIP_HUMAN relationship: has_participant CCO:B0058613 ! NALP1_HUMAN relationship: has_participant CCO:B0058693 ! LITFL_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN relationship: has_participant CCO:B0058911 ! TNR19_HUMAN relationship: has_participant CCO:B0058962 ! BCLF1_HUMAN relationship: has_participant CCO:B0059028 ! NDUAD_HUMAN relationship: has_participant CCO:B0059136 ! IL19_HUMAN relationship: has_participant CCO:B0059137 ! CIDEB_HUMAN relationship: has_participant CCO:B0059141 ! DDX20_HUMAN relationship: has_participant CCO:B0059148 ! S30BP_HUMAN relationship: has_participant CCO:B0059188 ! FEM1B_HUMAN relationship: has_participant CCO:B0059264 ! TRI35_HUMAN relationship: has_participant CCO:B0059334 ! UTP11_HUMAN [Term] id: CCO:P0000673 name: caspase activation namespace: biological_process def: "Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis." [GOC:jl, http://en.wikipedia.org/wiki/ "Wikipedia"] xref: GO:0006919 xref: Reactome:211794 xref: Reactome:221558 xref: Reactome:230166 xref: Reactome:69416 is_a: CCO:P0002178 ! positive regulation of caspase activity relationship: has_participant CCO:B0001370 ! FANCG_HUMAN relationship: has_participant CCO:B0001448 ! TNF15_HUMAN relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001520 ! ERF3A_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0006092 ! CH10_HUMAN relationship: has_participant CCO:B0006340 ! APR_HUMAN relationship: has_participant CCO:B0015966 ! IFNB_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN relationship: has_participant CCO:B0021834 ! MOAP1_HUMAN relationship: has_participant CCO:B0026744 ! B2L13_HUMAN relationship: has_participant CCO:B0035939 ! C8AP2_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0054870 ! CO9_HUMAN relationship: has_participant CCO:B0055574 ! NAL12_HUMAN relationship: has_participant CCO:B0055696 ! CO4A3_HUMAN relationship: has_participant CCO:B0056967 ! Q6W3F3_HUMAN relationship: has_participant CCO:B0057354 ! Q8IW90_HUMAN relationship: has_participant CCO:B0058613 ! NALP1_HUMAN relationship: has_participant CCO:B0058856 ! NLRC4_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN relationship: has_participant CCO:B0058936 ! IFT57_HUMAN relationship: has_participant CCO:B0059001 ! MTCH1_HUMAN relationship: part_of CCO:P0000839 ! apoptotic program [Term] id: CCO:P0000674 name: cell structure disassembly during apoptosis namespace: biological_process def: "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." [GOC:mah] synonym: "disassembly of cell structures" BROAD [] xref: GO:0006921 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0006340 ! APR_HUMAN relationship: has_participant CCO:B0021834 ! MOAP1_HUMAN relationship: part_of CCO:P0000839 ! apoptotic program [Term] id: CCO:P0000675 name: cleavage of lamin namespace: biological_process def: "The proteolytic degradation of lamins during apoptosis, leading to the irreversible breakdown of the nuclear lamina." [GOC:mah, ISBN:0815332181] xref: GO:0006922 is_a: CCO:P0000676 ! cleavage of cytoskeletal proteins during apoptosis relationship: has_participant CCO:B0054971 ! GRAB_HUMAN relationship: has_participant CCO:B0055002 ! GRAA_HUMAN [Term] id: CCO:P0000676 name: cleavage of cytoskeletal proteins during apoptosis namespace: biological_process def: "The proteolytic degradation of cytoskeletal proteins during apoptosis, leading to the collapse of cytoskeletal structures." [GOC:mah, ISBN:0815332181] synonym: "apoptotic cleavage of cytoskeletal proteins" EXACT [] xref: GO:0006923 is_a: CCO:P0000674 ! cell structure disassembly during apoptosis [Term] id: CCO:P0000677 name: negative regulation of cell adhesion involved in substrate-bound cell migration namespace: biological_process def: "The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction." [GOC:dph, GOC:tb, ISBN:0815316194, PMID:11944043, PMID:14657486] synonym: "substrate-bound cell migration, cell release from substrate" EXACT [GOC:dph, GOC:tb] xref: GO:0006933 is_a: CCO:P0000707 ! negative regulation of cell adhesion [Term] id: CCO:P0000678 name: substrate-bound cell migration, adhesion receptor recycling namespace: biological_process def: "The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions." [PMID:11944043] xref: GO:0006934 is_a: CCO:P0000486 ! receptor recycling relationship: part_of CCO:P0000677 ! negative regulation of cell adhesion involved in substrate-bound cell migration [Term] id: CCO:P0000679 name: positive regulation of antibacterial peptide biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis." [GOC:mah, PMID:10973475] synonym: "activation of antibacterial peptide biosynthetic process" NARROW [] synonym: "antibacterial peptide induction" EXACT [] synonym: "antibacterial polypeptide induction" EXACT [] synonym: "stimulation of antibacterial peptide biosynthetic process" NARROW [] synonym: "up regulation of antibacterial peptide biosynthetic process" EXACT [] synonym: "up-regulation of antibacterial peptide biosynthetic process" EXACT [] synonym: "upregulation of antibacterial peptide biosynthetic process" EXACT [] xref: GO:0006963 is_a: CCO:P0000591 ! positive regulation of antimicrobial peptide biosynthetic process is_a: CCO:P0000592 ! regulation of antibacterial peptide biosynthetic process [Term] id: CCO:P0000680 name: positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria." [GOC:mah, PMID:10973475] synonym: "activation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" NARROW [] synonym: "anti-Gram-negative bacterial peptide induction" EXACT [] synonym: "anti-Gram-negative bacterial polypeptide induction" EXACT [] synonym: "stimulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" NARROW [] synonym: "up regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] synonym: "up-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] synonym: "upregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria" EXACT [] xref: GO:0006964 is_a: CCO:P0000596 ! regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria is_a: CCO:P0000679 ! positive regulation of antibacterial peptide biosynthetic process [Term] id: CCO:P0000681 name: positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria." [GOC:mah, PMID:10973475] synonym: "activation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" NARROW [] synonym: "anti-Gram-positive bacterial peptide induction" EXACT [] synonym: "anti-Gram-positive bacterial polypeptide induction" EXACT [] synonym: "stimulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" NARROW [] synonym: "up regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] synonym: "up-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] synonym: "upregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria" EXACT [] xref: GO:0006965 is_a: CCO:P0000598 ! regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria is_a: CCO:P0000679 ! positive regulation of antibacterial peptide biosynthetic process relationship: has_participant CCO:B0055655 ! D103A_HUMAN [Term] id: CCO:P0000682 name: positive regulation of antifungal peptide biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis." [GOC:mah] synonym: "activation of antifungal peptide biosynthetic process" NARROW [] synonym: "antifungal peptide induction" EXACT [] synonym: "antifungal polypeptide induction" EXACT [] synonym: "stimulation of antifungal peptide biosynthetic process" NARROW [] synonym: "up regulation of antifungal peptide biosynthetic process" EXACT [] synonym: "up-regulation of antifungal peptide biosynthetic process" EXACT [] synonym: "upregulation of antifungal peptide biosynthetic process" EXACT [] xref: GO:0006967 is_a: CCO:P0000591 ! positive regulation of antimicrobial peptide biosynthetic process is_a: CCO:P0000594 ! regulation of antifungal peptide biosynthetic process [Term] id: CCO:P0000683 name: DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator namespace: biological_process def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage." [PMID:10967424] xref: GO:0006978 is_a: CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator is_a: CCO:P0002127 ! DNA damage response, signal transduction resulting in transcription relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0017902 ! RBM38_HUMAN [Term] id: CCO:P0000684 name: ER overload response namespace: biological_process def: "The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB." [PMID:10390516] synonym: "endoplasmic reticulum overload response" EXACT [] synonym: "EOR" EXACT [] synonym: "ER stress response" BROAD [] synonym: "ER-overload response" EXACT [] xref: GO:0006983 is_a: CCO:P0000685 ! ER-nuclear signaling pathway relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0054687 ! WFS1_HUMAN relationship: has_participant CCO:B0058480 ! SELS_HUMAN [Term] id: CCO:P0000685 name: ER-nuclear signaling pathway namespace: biological_process def: "Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation." [GOC:mah] synonym: "endoplasmic reticulum to nucleus signaling pathway" EXACT [] synonym: "endoplasmic reticulum-nuclear signaling pathway" EXACT [] synonym: "ER to nucleus signaling pathway" EXACT [] synonym: "ER to nucleus signalling pathway" EXACT [] synonym: "ER-nuclear signalling pathway" EXACT [] xref: GO:0006984 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0005469 ! PAK1_HUMAN relationship: has_participant CCO:B0005840 ! AT2A2_HUMAN relationship: has_participant CCO:B0057431 ! CRPAK_HUMAN [Term] id: CCO:P0000686 name: positive regulation of NF-kappaB transcription factor activity by ER overload response namespace: biological_process def: "The conversion of inactive NF-kappaB to the active form, thereby allowing it to activate transcription of target genes, as a result of signaling from the endoplasmic reticulum." [GOC:dph, GOC:mah, GOC:tb, PMID:10390516] synonym: "EOR-mediated activation of NF-kappaB " EXACT [GOC:dph, GOC:tb] synonym: "EOR-mediated NF-kappaB activation" EXACT [] synonym: "positive regulation of NF-kappaB transcription factor activity by EOR" EXACT [GOC:dph, GOC:tb] xref: GO:0006985 is_a: CCO:P0003023 ! positive regulation of NF-kappaB transcription factor activity relationship: part_of CCO:P0000684 ! ER overload response [Term] id: CCO:P0000687 name: activation of signaling protein activity involved in unfolded protein response namespace: biological_process def: "The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response." [GOC:dph, GOC:mah, GOC:tb, PMID:12042763] synonym: "unfolded protein response, activation of signaling protein activity" EXACT [GOC:dph, GOC:tb] synonym: "unfolded protein response, activation of signaling protein kinase/endonuclease" EXACT [] synonym: "unfolded protein response, activation of signalling protein kinase/endonuclease" EXACT [] xref: GO:0006987 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001428 ! ERN1_HUMAN relationship: part_of CCO:P0001358 ! endoplasmic reticulum unfolded protein response [Term] id: CCO:P0000688 name: positive regulation of gene-specific transcription involved in unfolded protein response namespace: biological_process def: "The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensu thes CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response." [GOC:dph, GOC:mah, GOC:tb, PMID:12042763] synonym: "positive regulation of transcription of target genes involved in unfolded protein response" EXACT [GOC:dph, GOC:tb] synonym: "unfolded protein response, activation of target gene transcription" NARROW [] synonym: "unfolded protein response, positive regulation of target gene transcription" EXACT [GOC:tb] synonym: "unfolded protein response, stimulation of target gene transcription" NARROW [] synonym: "unfolded protein response, target gene transcriptional activation" BROAD [] synonym: "unfolded protein response, up regulation of target gene transcription" EXACT [] synonym: "unfolded protein response, up-regulation of target gene transcription" EXACT [] synonym: "unfolded protein response, upregulation of target gene transcription" EXACT [] xref: GO:0006990 is_a: CCO:P0002172 ! positive regulation of gene-specific transcription is_a: CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0018951 ! ATF6A_HUMAN relationship: part_of CCO:P0001358 ! endoplasmic reticulum unfolded protein response [Term] id: CCO:P0000689 name: sterol depletion response, sterol regulatory element binding protein cleavage namespace: biological_process def: "The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus and upregulate transcription of target genes, in response to depleted sterol levels." [GOC:bf, PMID:12923525] synonym: "sterol depletion response, SREBP cleavage" EXACT [] xref: GO:0006992 is_a: CCO:P0001996 ! sterol regulatory element binding protein cleavage relationship: part_of CCO:P0001357 ! ER-nuclear sterol response pathway [Term] id: CCO:P0000690 name: sterol depletion response, sterol regulatory element binding protein nuclear translocation namespace: biological_process def: "The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus across the nuclear membrane, in response to sterol depletion. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, PMID:12923525] synonym: "sterol depletion response, SREBP nuclear translocation" EXACT [] xref: GO:0006993 is_a: CCO:P0001998 ! sterol regulatory element binding protein nuclear translocation relationship: part_of CCO:P0001357 ! ER-nuclear sterol response pathway [Term] id: CCO:P0000691 name: positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response namespace: biological_process def: "The process by which a sterol regulatory element binding protein (SREBP) mediates an increase in rate or extent of transcription of nuclear target genes in response to sterol depletion. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, PMID:12923525] synonym: "sterol depletion response, SREBP target gene transcriptional activation" EXACT [GOC:dph, GOC:mtg_lung] xref: GO:0006994 is_a: CCO:P0001997 ! positive regulation of sterol regulatory element binding protein target gene transcription relationship: has_participant CCO:B0055838 ! SCAP_HUMAN relationship: part_of CCO:P0001357 ! ER-nuclear sterol response pathway [Term] id: CCO:P0000692 name: telomere maintenance via telomerase namespace: biological_process def: "The maintenace of proper telomeric length by the addition of telomeric repeats by telomerase." [GOC:elh] synonym: "telomerase-dependent telomere maintenance" EXACT [] xref: GO:0007004 xref: Reactome:163090 xref: Reactome:163096 xref: Reactome:163099 xref: Reactome:163120 xref: Reactome:164616 xref: Reactome:164617 xref: Reactome:164620 xref: Reactome:171319 xref: Reactome:204681 xref: Reactome:207368 xref: Reactome:207812 xref: Reactome:207815 xref: Reactome:210720 xref: Reactome:211317 xref: Reactome:211638 xref: Reactome:213765 xref: Reactome:216960 xref: Reactome:217340 xref: Reactome:217343 xref: Reactome:220611 xref: Reactome:221126 xref: Reactome:221410 xref: Reactome:223502 xref: Reactome:225815 xref: Reactome:226015 xref: Reactome:226016 xref: Reactome:229293 xref: Reactome:229780 xref: Reactome:230045 xref: Reactome:231985 xref: Reactome:234484 xref: Reactome:234714 xref: Reactome:234717 xref: Reactome:237268 xref: Reactome:237781 xref: Reactome:238063 xref: Reactome:250481 xref: Reactome:251276 xref: Reactome:251340 xref: Reactome:251341 xref: Reactome:252051 xref: Reactome:252274 xref: Reactome:252403 xref: Reactome:253320 xref: Reactome:254353 xref: Reactome:254423 xref: Reactome:254433 xref: Reactome:255254 xref: Reactome:255428 xref: Reactome:255561 xref: Reactome:256500 xref: Reactome:257473 xref: Reactome:257575 xref: Reactome:257585 xref: Reactome:258550 xref: Reactome:258778 xref: Reactome:258935 xref: Reactome:259951 xref: Reactome:261147 xref: Reactome:261239 xref: Reactome:261249 xref: Reactome:261963 xref: Reactome:262182 xref: Reactome:262309 xref: Reactome:263242 xref: Reactome:264067 xref: Reactome:264128 xref: Reactome:264129 xref: Reactome:264762 xref: Reactome:264997 xref: Reactome:265160 xref: Reactome:266139 xref: Reactome:267091 xref: Reactome:267162 xref: Reactome:267163 xref: Reactome:267939 xref: Reactome:268129 xref: Reactome:268286 xref: Reactome:269901 xref: Reactome:272146 xref: Reactome:272282 xref: Reactome:272292 xref: Reactome:273491 xref: Reactome:273780 xref: Reactome:273967 xref: Reactome:275803 xref: Reactome:278135 xref: Reactome:278288 xref: Reactome:278298 xref: Reactome:279958 xref: Reactome:280233 xref: Reactome:280446 xref: Reactome:283872 xref: Reactome:285016 xref: Reactome:285107 xref: Reactome:285117 xref: Reactome:286058 xref: Reactome:286303 xref: Reactome:286468 is_a: CCO:P0000641 ! RNA-dependent DNA replication relationship: has_participant CCO:B0001415 ! DKC1_HUMAN relationship: has_participant CCO:B0001641 ! MRE11_HUMAN relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0002021 ! RAD50_HUMAN relationship: has_participant CCO:B0005503 ! POTE1_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN relationship: has_participant CCO:B0005887 ! RFC1_HUMAN relationship: has_participant CCO:B0006245 ! TINF2_HUMAN relationship: has_participant CCO:B0014982 ! TB182_HUMAN relationship: has_participant CCO:B0027184 ! Q6ZQQ5_HUMAN relationship: has_participant CCO:B0038614 ! A6NJ87_HUMAN relationship: has_participant CCO:B0054745 ! TNKS1_HUMAN [Term] id: CCO:P0000693 name: negative regulation of microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." [GOC:mah, ISBN:0815316194] synonym: "down regulation of microtubule depolymerization" EXACT [] synonym: "down-regulation of microtubule depolymerization" EXACT [] synonym: "downregulation of microtubule depolymerization" EXACT [] synonym: "inhibition of microtubule depolymerization" NARROW [] synonym: "microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule disassembly" EXACT [] xref: GO:0007026 is_a: CCO:P0001381 ! negative regulation of microtubule polymerization or depolymerization is_a: CCO:P0001384 ! regulation of microtubule depolymerization is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process relationship: has_participant CCO:B0001422 ! CLAP2_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001933 ! CLAP1_HUMAN relationship: has_participant CCO:B0002100 ! KTNB1_HUMAN relationship: has_participant CCO:B0005281 ! M1IP1_HUMAN relationship: has_participant CCO:B0050955 ! MAP2_HUMAN relationship: has_participant CCO:B0054976 ! TAU_HUMAN relationship: has_participant CCO:B0055196 ! MAP4_HUMAN relationship: has_participant CCO:B0055380 ! MAP1B_HUMAN relationship: has_participant CCO:B0056135 ! Q16296_HUMAN relationship: has_participant CCO:B0056188 ! Q17S04_HUMAN relationship: has_participant CCO:B0057329 ! Q8IUX2_HUMAN relationship: has_participant CCO:B0057579 ! Q8NDS5_HUMAN relationship: has_participant CCO:B0057897 ! Q8TB56_HUMAN relationship: has_participant CCO:B0057924 ! Q8TDA3_HUMAN relationship: has_participant CCO:B0058583 ! TRI54_HUMAN relationship: has_participant CCO:B0058647 ! Q9H023_HUMAN relationship: has_participant CCO:B0058755 ! MA6D1_HUMAN [Term] id: CCO:P0000694 name: negative regulation of microtubule depolymerization in axoneme namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." [GOC:dph, GOC:mah] synonym: "axonemal microtubule stabilization" EXACT [] synonym: "negative regulation of axonemal microtubule depolymerization" RELATED [GOC:dph] xref: GO:0007027 is_a: CCO:P0000693 ! negative regulation of microtubule depolymerization [Term] id: CCO:P0000695 name: chromosome segregation namespace: biological_process def: "The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] subset: goslim_pir subset: gosubset_prok synonym: "chromosome division" EXACT [] synonym: "chromosome transmission" RELATED [] xref: GO:0007059 is_a: CCO:P0000887 ! cellular process relationship: has_participant CCO:B0001396 ! BUB3_HUMAN relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001447 ! REC8_HUMAN relationship: has_participant CCO:B0001457 ! PTTG1_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0001787 ! ESPL1_HUMAN relationship: has_participant CCO:B0001840 ! SGOL2_HUMAN relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002043 ! NSL1_HUMAN relationship: has_participant CCO:B0002061 ! SRPK1_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002122 ! MIS12_HUMAN relationship: has_participant CCO:B0002134 ! DSN1_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0002209 ! STAG3_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0006324 ! ARL8B_HUMAN relationship: has_participant CCO:B0051572 ! RIOK3_HUMAN relationship: has_participant CCO:B0055439 ! PSN2_HUMAN relationship: has_participant CCO:B0058166 ! ARL8A_HUMAN [Term] id: CCO:P0000696 name: cytokinesis, site selection namespace: biological_process def: "The process of marking the place where cytokinesis will occur." [GOC:clt, GOC:dph, GOC:tb] subset: gosubset_prok synonym: "actomyosin ring positioning" NARROW [] synonym: "contractile ring positioning" NARROW [] synonym: "site selection involved in cytokinesis" EXACT [GOC:dph, GOC:tb] xref: GO:0007105 is_a: CCO:P0001637 ! cytokinetic process [Term] id: CCO:P0000697 name: membrane addition at site of cytokinesis namespace: biological_process def: "Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion." [GOC:clt] synonym: "cytokinesis, membrane recruitment/generation" EXACT [] xref: GO:0007107 is_a: CCO:P0001637 ! cytokinetic process [Term] id: CCO:P0000698 name: cytokinesis, initiation of separation namespace: biological_process def: "The process involved in starting cell separation." [GOC:clt, GOC:dph, GOC:tb] synonym: "initiation of separation involved in cytokinesis" EXACT [GOC:dph, GOC:tb] xref: GO:0007108 is_a: CCO:P0001637 ! cytokinetic process relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN relationship: part_of CCO:P0000456 ! cell separation during cytokinesis [Term] id: CCO:P0000699 name: cytokinesis, completion of separation namespace: biological_process def: "The process of finishing cell separation, which results in two physically separated cells." [GOC:clt, GOC:dph, GOC:tb] synonym: "completion of separation involved in cytokinesis" EXACT [GOC:dph, GOC:tb] xref: GO:0007109 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000456 ! cell separation during cytokinesis [Term] id: CCO:P0000700 name: cell budding namespace: biological_process def: "A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: goslim_candida subset: goslim_yeast subset: gosubset_prok synonym: "budding" BROAD [] xref: GO:0007114 is_a: CCO:P0001636 ! reproduction of a single-celled organism [Term] id: CCO:P0000701 name: regulation of cell budding namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation and growth of cell buds." [GOC:mah] synonym: "regulation of budding" BROAD [] xref: GO:0007116 is_a: CCO:P0003078 ! regulation of cell division relationship: regulates CCO:P0000700 ! cell budding [Term] id: CCO:P0000702 name: budding cell bud growth namespace: biological_process def: "The process by which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:go_curators] synonym: "bud growth" BROAD [] xref: GO:0007117 is_a: CCO:P0001240 ! reproductive process in single-celled organism relationship: part_of CCO:P0000700 ! cell budding [Term] id: CCO:P0000703 name: budding cell apical bud growth namespace: biological_process def: "Growth at the tip of a bud, in a cell that reproduces by budding." [GOC:go_curators] synonym: "apical bud growth" BROAD [] xref: GO:0007118 is_a: CCO:P0000702 ! budding cell bud growth [Term] id: CCO:P0000704 name: budding cell isotropic bud growth namespace: biological_process def: "Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding." [GOC:go_curators] synonym: "isotropic bud growth" BROAD [] xref: GO:0007119 is_a: CCO:P0000702 ! budding cell bud growth [Term] id: CCO:P0000705 name: axial cellular bud site selection namespace: biological_process def: "The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell." [GOC:clt] synonym: "axial bud site selection" EXACT [] synonym: "axial budding" BROAD [] xref: GO:0007120 is_a: CCO:P0000421 ! cellular bud site selection is_a: CCO:P0000700 ! cell budding [Term] id: CCO:P0000706 name: bipolar cellular bud site selection namespace: biological_process def: "The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell." [GOC:clt] synonym: "bipolar bud site selection" EXACT [] synonym: "bipolar budding" BROAD [] synonym: "polar budding" BROAD [] xref: GO:0007121 is_a: CCO:P0000421 ! cellular bud site selection is_a: CCO:P0000700 ! cell budding [Term] id: CCO:P0000707 name: negative regulation of cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "cell adhesion receptor inhibitor activity" RELATED [] synonym: "down regulation of cell adhesion" EXACT [] synonym: "down-regulation of cell adhesion" EXACT [] synonym: "downregulation of cell adhesion" EXACT [] synonym: "inhibition of cell adhesion" NARROW [] xref: GO:0007162 is_a: CCO:P0001245 ! regulation of cell adhesion is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0002039 ! SIPA1_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0024051 ! ADEC1_HUMAN relationship: has_participant CCO:B0030278 ! RND1_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN relationship: has_participant CCO:B0037751 ! BGH3_HUMAN relationship: has_participant CCO:B0038558 ! ADA22_HUMAN relationship: has_participant CCO:B0054336 ! PODXL_HUMAN relationship: has_participant CCO:B0054364 ! ADA10_HUMAN relationship: has_participant CCO:B0054832 ! KNG1_HUMAN relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055486 ! GDIR2_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0056463 ! MIA3_HUMAN relationship: has_participant CCO:B0057600 ! Q8NFD8_HUMAN relationship: has_participant CCO:B0058457 ! GDIR3_HUMAN relationship: has_participant CCO:B0058883 ! Q9NR26_HUMAN [Term] id: CCO:P0000708 name: signal transduction namespace: biological_process def: "The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately effecting a change in the functioning of the cell." [GOC:go_curators] subset: goslim_candida subset: goslim_generic subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "signaling" EXACT [] synonym: "signaling cascade" EXACT [] synonym: "signalling" EXACT [] synonym: "signalling cascade" EXACT [] xref: GO:0007165 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0001399 ! AKAP8_HUMAN relationship: has_participant CCO:B0001406 ! ADCY3_HUMAN relationship: has_participant CCO:B0001437 ! BCAR3_HUMAN relationship: has_participant CCO:B0001448 ! TNF15_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001479 ! ANXA1_HUMAN relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001500 ! FGF4_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001504 ! IL8_HUMAN relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0001509 ! FGF6_HUMAN relationship: has_participant CCO:B0001511 ! FGF3_HUMAN relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0001527 ! PP2BB_HUMAN relationship: has_participant CCO:B0001528 ! STMN1_HUMAN relationship: has_participant CCO:B0001537 ! CSK22_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001544 ! MK_HUMAN relationship: has_participant CCO:B0001545 ! FGF7_HUMAN relationship: has_participant CCO:B0001549 ! CRCM_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001579 ! UFO_HUMAN relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001610 ! PK3CB_HUMAN relationship: has_participant CCO:B0001611 ! FRAP_HUMAN relationship: has_participant CCO:B0001633 ! PLGF_HUMAN relationship: has_participant CCO:B0001634 ! VEGFB_HUMAN relationship: has_participant CCO:B0001635 ! VEGFC_HUMAN relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0001646 ! RASF2_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001658 ! MP2K6_HUMAN relationship: has_participant CCO:B0001665 ! MK12_HUMAN relationship: has_participant CCO:B0001674 ! FGF8_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0001747 ! KGP2_HUMAN relationship: has_participant CCO:B0001750 ! ATM_HUMAN relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0001764 ! ASPP2_HUMAN relationship: has_participant CCO:B0001765 ! PTC1_HUMAN relationship: has_participant CCO:B0001782 ! CASL_HUMAN relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0001818 ! EXT1_HUMAN relationship: has_participant CCO:B0001822 ! MK06_HUMAN relationship: has_participant CCO:B0001899 ! DAB2P_HUMAN relationship: has_participant CCO:B0001980 ! DP13B_HUMAN relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0002008 ! RASF5_HUMAN relationship: has_participant CCO:B0002028 ! EXT2_HUMAN relationship: has_participant CCO:B0002039 ! SIPA1_HUMAN relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN relationship: has_participant CCO:B0002129 ! RASF4_HUMAN relationship: has_participant CCO:B0002151 ! PLCB1_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0002188 ! RHG20_HUMAN relationship: has_participant CCO:B0002193 ! KS6B2_HUMAN relationship: has_participant CCO:B0002219 ! DP13A_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0002232 ! SUFU_HUMAN relationship: has_participant CCO:B0002236 ! GP132_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0002253 ! STA13_HUMAN relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005235 ! HNRPK_HUMAN relationship: has_participant CCO:B0005272 ! KC1E_HUMAN relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005342 ! DEK_HUMAN relationship: has_participant CCO:B0005350 ! TRRAP_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005366 ! ACL6A_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005385 ! RIN1_HUMAN relationship: has_participant CCO:B0005394 ! FEZ2_HUMAN relationship: has_participant CCO:B0005413 ! 1433Z_HUMAN relationship: has_participant CCO:B0005428 ! CSK21_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005438 ! MET_HUMAN relationship: has_participant CCO:B0005447 ! NRP1_HUMAN relationship: has_participant CCO:B0005455 ! CD166_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005476 ! SH22A_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN relationship: has_participant CCO:B0005506 ! FSHR_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005515 ! 2A5D_HUMAN relationship: has_participant CCO:B0005516 ! 2A5A_HUMAN relationship: has_participant CCO:B0005518 ! 2A5E_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005537 ! IKBB_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005546 ! CELR3_HUMAN relationship: has_participant CCO:B0005547 ! PLXB3_HUMAN relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005564 ! RHG18_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN relationship: has_participant CCO:B0005588 ! AKAP9_HUMAN relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0005610 ! PLCG1_HUMAN relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0005630 ! ANM2_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005638 ! MK08_HUMAN relationship: has_participant CCO:B0005646 ! FGFP1_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0005653 ! RANG_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN relationship: has_participant CCO:B0005661 ! IPO7_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005681 ! CREB1_HUMAN relationship: has_participant CCO:B0005685 ! ABL2_HUMAN relationship: has_participant CCO:B0005690 ! TLE3_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0005702 ! STK4_HUMAN relationship: has_participant CCO:B0005704 ! ZYX_HUMAN relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0005723 ! MTR1A_HUMAN relationship: has_participant CCO:B0005724 ! MTR1B_HUMAN relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN relationship: has_participant CCO:B0005806 ! OGT1_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN relationship: has_participant CCO:B0005819 ! CBLB_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN relationship: has_participant CCO:B0005832 ! EPHA2_HUMAN relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0005846 ! FAK2_HUMAN relationship: has_participant CCO:B0005849 ! KI13B_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0005872 ! AAPK1_HUMAN relationship: has_participant CCO:B0005891 ! MAPK5_HUMAN relationship: has_participant CCO:B0005892 ! MK11_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0005911 ! AKT3_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0005913 ! BRAF1_HUMAN relationship: has_participant CCO:B0005914 ! AFAD_HUMAN relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0005949 ! AGRIN_HUMAN relationship: has_participant CCO:B0005951 ! BRE_HUMAN relationship: has_participant CCO:B0005954 ! DTNA_HUMAN relationship: has_participant CCO:B0005961 ! GRN_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0006010 ! TNR8_HUMAN relationship: has_participant CCO:B0006033 ! ARNT2_HUMAN relationship: has_participant CCO:B0006039 ! SMO_HUMAN relationship: has_participant CCO:B0006068 ! PKN1_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN relationship: has_participant CCO:B0006077 ! EPAS1_HUMAN relationship: has_participant CCO:B0006087 ! CCL18_HUMAN relationship: has_participant CCO:B0006108 ! SPB9_HUMAN relationship: has_participant CCO:B0006119 ! ANXA3_HUMAN relationship: has_participant CCO:B0006123 ! BCR_HUMAN relationship: has_participant CCO:B0006142 ! GBB5_HUMAN relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0006187 ! SH3G3_HUMAN relationship: has_participant CCO:B0006188 ! SH3G2_HUMAN relationship: has_participant CCO:B0006198 ! CENPR_HUMAN relationship: has_participant CCO:B0006207 ! MPP3_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN relationship: has_participant CCO:B0006252 ! ULK2_HUMAN relationship: has_participant CCO:B0006263 ! GLHA_HUMAN relationship: has_participant CCO:B0006292 ! PLXB2_HUMAN relationship: has_participant CCO:B0006306 ! GP135_HUMAN relationship: has_participant CCO:B0006310 ! SH3G1_HUMAN relationship: has_participant CCO:B0006317 ! GABR1_HUMAN relationship: has_participant CCO:B0006332 ! INPP_HUMAN relationship: has_participant CCO:B0006352 ! STRN4_HUMAN relationship: has_participant CCO:B0014816 ! KGP1A_HUMAN relationship: has_participant CCO:B0014822 ! KGP1B_HUMAN relationship: has_participant CCO:B0014942 ! EPHA4_HUMAN relationship: has_participant CCO:B0014967 ! EPHA3_HUMAN relationship: has_participant CCO:B0014968 ! EPHB3_HUMAN relationship: has_participant CCO:B0014969 ! EPHB1_HUMAN relationship: has_participant CCO:B0014973 ! EPHA1_HUMAN relationship: has_participant CCO:B0015018 ! PPIP1_HUMAN relationship: has_participant CCO:B0015122 ! GLR_HUMAN relationship: has_participant CCO:B0015123 ! GLP1R_HUMAN relationship: has_participant CCO:B0015124 ! GIPR_HUMAN relationship: has_participant CCO:B0015126 ! Q8NHB4_HUMAN relationship: has_participant CCO:B0015134 ! GLP2R_HUMAN relationship: has_participant CCO:B0015136 ! SCTR_HUMAN relationship: has_participant CCO:B0015164 ! HHIP_HUMAN relationship: has_participant CCO:B0015673 ! CHL1_HUMAN relationship: has_participant CCO:B0015779 ! PILRA_HUMAN relationship: has_participant CCO:B0015822 ! ANXA5_HUMAN relationship: has_participant CCO:B0015859 ! ANXA4_HUMAN relationship: has_participant CCO:B0016329 ! AAKG1_HUMAN relationship: has_participant CCO:B0016356 ! Q6KH11_HUMAN relationship: has_participant CCO:B0016357 ! Q6PCE1_HUMAN relationship: has_participant CCO:B0016367 ! RGL3_HUMAN relationship: has_participant CCO:B0016368 ! Q8TEP0_HUMAN relationship: has_participant CCO:B0016369 ! Q6ZSD5_HUMAN relationship: has_participant CCO:B0016370 ! Q8TEK8_HUMAN relationship: has_participant CCO:B0016540 ! KCC4_HUMAN relationship: has_participant CCO:B0016545 ! KCC2B_HUMAN relationship: has_participant CCO:B0016556 ! KCC1A_HUMAN relationship: has_participant CCO:B0016638 ! Q0VAF8_HUMAN relationship: has_participant CCO:B0016650 ! FCERB_HUMAN relationship: has_participant CCO:B0016681 ! ANPRB_HUMAN relationship: has_participant CCO:B0016789 ! Q7Z5R8_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0016804 ! Q308M4_HUMAN relationship: has_participant CCO:B0016805 ! PDK4_HUMAN relationship: has_participant CCO:B0016807 ! PDK1_HUMAN relationship: has_participant CCO:B0016810 ! PDK3_HUMAN relationship: has_participant CCO:B0016811 ! PDK2_HUMAN relationship: has_participant CCO:B0016974 ! PK2L1_HUMAN relationship: has_participant CCO:B0016983 ! Q8NH25_HUMAN relationship: has_participant CCO:B0016986 ! P2RY8_HUMAN relationship: has_participant CCO:B0017118 ! ING2_HUMAN relationship: has_participant CCO:B0017140 ! NEU2_HUMAN relationship: has_participant CCO:B0017141 ! NEU1_HUMAN relationship: has_participant CCO:B0017343 ! Q15300_HUMAN relationship: has_participant CCO:B0017344 ! RET_HUMAN relationship: has_participant CCO:B0017481 ! KC1D_HUMAN relationship: has_participant CCO:B0017509 ! FGF20_HUMAN relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN relationship: has_participant CCO:B0017668 ! FGF12_HUMAN relationship: has_participant CCO:B0017671 ! FGF16_HUMAN relationship: has_participant CCO:B0017676 ! FGF13_HUMAN relationship: has_participant CCO:B0017677 ! FGF14_HUMAN relationship: has_participant CCO:B0017679 ! FGF11_HUMAN relationship: has_participant CCO:B0017773 ! T2R40_HUMAN relationship: has_participant CCO:B0017845 ! LPXN_HUMAN relationship: has_participant CCO:B0018024 ! ZPR1_HUMAN relationship: has_participant CCO:B0018166 ! ICK_HUMAN relationship: has_participant CCO:B0018345 ! O00334_HUMAN relationship: has_participant CCO:B0018350 ! PK3CA_HUMAN relationship: has_participant CCO:B0018352 ! PK3CD_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN relationship: has_participant CCO:B0018391 ! IQGA2_HUMAN relationship: has_participant CCO:B0018395 ! IQGA3_HUMAN relationship: has_participant CCO:B0018438 ! CCRL1_HUMAN relationship: has_participant CCO:B0018440 ! CCR10_HUMAN relationship: has_participant CCO:B0018485 ! CLTR2_HUMAN relationship: has_participant CCO:B0018486 ! CLTR1_HUMAN relationship: has_participant CCO:B0018534 ! KAPCB_HUMAN relationship: has_participant CCO:B0018655 ! RYK_HUMAN relationship: has_participant CCO:B0018692 ! Q5W0G9_HUMAN relationship: has_participant CCO:B0018695 ! EDNRA_HUMAN relationship: has_participant CCO:B0018697 ! EDNRB_HUMAN relationship: has_participant CCO:B0018770 ! M3K10_HUMAN relationship: has_participant CCO:B0018951 ! ATF6A_HUMAN relationship: has_participant CCO:B0018956 ! RASF3_HUMAN relationship: has_participant CCO:B0019045 ! EM55_HUMAN relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0019132 ! RHG17_HUMAN relationship: has_participant CCO:B0019134 ! A6NCP5_HUMAN relationship: has_participant CCO:B0019135 ! RICH2_HUMAN relationship: has_participant CCO:B0019340 ! SYGP1_HUMAN relationship: has_participant CCO:B0019348 ! A2AB18_HUMAN relationship: has_participant CCO:B0019350 ! NGAP_HUMAN relationship: has_participant CCO:B0019358 ! RASF6_HUMAN relationship: has_participant CCO:B0019359 ! Q8IZA5_HUMAN relationship: has_participant CCO:B0019360 ! Q59FL4_HUMAN relationship: has_participant CCO:B0019383 ! RHG05_HUMAN relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0019877 ! Q7KZS6_HUMAN relationship: has_participant CCO:B0020112 ! FCN2_HUMAN relationship: has_participant CCO:B0020113 ! FBCD1_HUMAN relationship: has_participant CCO:B0020115 ! ANGL5_HUMAN relationship: has_participant CCO:B0020117 ! Q92531_HUMAN relationship: has_participant CCO:B0020119 ! Q68DD1_HUMAN relationship: has_participant CCO:B0020121 ! A3KFJ8_HUMAN relationship: has_participant CCO:B0020122 ! FCN1_HUMAN relationship: has_participant CCO:B0020123 ! MFAP4_HUMAN relationship: has_participant CCO:B0020207 ! KCIP1_HUMAN relationship: has_participant CCO:B0020218 ! CSEN_HUMAN relationship: has_participant CCO:B0020223 ! KCIP2_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0020370 ! TGFR1_HUMAN relationship: has_participant CCO:B0020414 ! KC1G3_HUMAN relationship: has_participant CCO:B0020420 ! KC1G2_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN relationship: has_participant CCO:B0020601 ! GRIA2_HUMAN relationship: has_participant CCO:B0020627 ! GRIA1_HUMAN relationship: has_participant CCO:B0020731 ! TAGAP_HUMAN relationship: has_participant CCO:B0020780 ! RGS1_HUMAN relationship: has_participant CCO:B0020855 ! GTPB1_HUMAN relationship: has_participant CCO:B0020879 ! ADCY7_HUMAN relationship: has_participant CCO:B0020948 ! MP2K3_HUMAN relationship: has_participant CCO:B0020951 ! MP2K7_HUMAN relationship: has_participant CCO:B0021009 ! Q9UHS4_HUMAN relationship: has_participant CCO:B0021015 ! Q5TBX5_HUMAN relationship: has_participant CCO:B0021018 ! PKN3_HUMAN relationship: has_participant CCO:B0021020 ! PKN2_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0021202 ! A2A3C6_HUMAN relationship: has_participant CCO:B0021203 ! A2A3C1_HUMAN relationship: has_participant CCO:B0021208 ! A2A3C2_HUMAN relationship: has_participant CCO:B0021209 ! A2A3C3_HUMAN relationship: has_participant CCO:B0021210 ! BAI2_HUMAN relationship: has_participant CCO:B0021303 ! ZFAN6_HUMAN relationship: has_participant CCO:B0021337 ! KAP1_HUMAN relationship: has_participant CCO:B0021338 ! Q8N422_HUMAN relationship: has_participant CCO:B0021417 ! CALRL_HUMAN relationship: has_participant CCO:B0021419 ! A4D1G6_HUMAN relationship: has_participant CCO:B0021671 ! HBEGF_HUMAN relationship: has_participant CCO:B0021692 ! WISP1_HUMAN relationship: has_participant CCO:B0021699 ! WISP2_HUMAN relationship: has_participant CCO:B0022069 ! Q5VZI8_HUMAN relationship: has_participant CCO:B0022071 ! TLR4_HUMAN relationship: has_participant CCO:B0022449 ! A2I2N5_HUMAN relationship: has_participant CCO:B0022450 ! Q5H8X5_HUMAN relationship: has_participant CCO:B0022451 ! Q8TAR6_HUMAN relationship: has_participant CCO:B0022452 ! PER3_HUMAN relationship: has_participant CCO:B0022454 ! KAP3_HUMAN relationship: has_participant CCO:B0022455 ! KAP2_HUMAN relationship: has_participant CCO:B0022458 ! Q9BUB1_HUMAN relationship: has_participant CCO:B0022719 ! Q6IF88_HUMAN relationship: has_participant CCO:B0022721 ! OR5K3_HUMAN relationship: has_participant CCO:B0022723 ! OR5K1_HUMAN relationship: has_participant CCO:B0022725 ! Q8NHB6_HUMAN relationship: has_participant CCO:B0022726 ! O5AC2_HUMAN relationship: has_participant CCO:B0022728 ! OR5H1_HUMAN relationship: has_participant CCO:B0022729 ! O5H15_HUMAN relationship: has_participant CCO:B0022730 ! Q6IF87_HUMAN relationship: has_participant CCO:B0022731 ! OR5K2_HUMAN relationship: has_participant CCO:B0022743 ! STK24_HUMAN relationship: has_participant CCO:B0022748 ! STK25_HUMAN relationship: has_participant CCO:B0022762 ! CASS4_HUMAN relationship: has_participant CCO:B0022838 ! Q8NEI9_HUMAN relationship: has_participant CCO:B0022839 ! Q8NHC0_HUMAN relationship: has_participant CCO:B0022840 ! Q8NH98_HUMAN relationship: has_participant CCO:B0022842 ! Q8NH65_HUMAN relationship: has_participant CCO:B0022843 ! Q9UPJ0_HUMAN relationship: has_participant CCO:B0022845 ! Q8NHB5_HUMAN relationship: has_participant CCO:B0022847 ! Q8NH99_HUMAN relationship: has_participant CCO:B0022848 ! Q9P1R1_HUMAN relationship: has_participant CCO:B0022849 ! Q8NH46_HUMAN relationship: has_participant CCO:B0022852 ! Q8NGT4_HUMAN relationship: has_participant CCO:B0022854 ! Q8NHC1_HUMAN relationship: has_participant CCO:B0022857 ! Q8NHB9_HUMAN relationship: has_participant CCO:B0022858 ! Q8NH45_HUMAN relationship: has_participant CCO:B0022861 ! O7E24_HUMAN relationship: has_participant CCO:B0022862 ! Q9UDD8_HUMAN relationship: has_participant CCO:B0022865 ! Q8NHA1_HUMAN relationship: has_participant CCO:B0022866 ! Q8NG89_HUMAN relationship: has_participant CCO:B0022870 ! Q96N54_HUMAN relationship: has_participant CCO:B0022873 ! Q8NGD7_HUMAN relationship: has_participant CCO:B0022899 ! GBRR2_HUMAN relationship: has_participant CCO:B0022903 ! GBRT_HUMAN relationship: has_participant CCO:B0022907 ! GBRA6_HUMAN relationship: has_participant CCO:B0022915 ! GBRA5_HUMAN relationship: has_participant CCO:B0022931 ! GBRD_HUMAN relationship: has_participant CCO:B0022985 ! FGF17_HUMAN relationship: has_participant CCO:B0022986 ! FGF18_HUMAN relationship: has_participant CCO:B0023311 ! DLG4_HUMAN relationship: has_participant CCO:B0023418 ! STAT4_HUMAN relationship: has_participant CCO:B0023422 ! STAT2_HUMAN relationship: has_participant CCO:B0023430 ! Q67C41_HUMAN relationship: has_participant CCO:B0023770 ! NOSTN_HUMAN relationship: has_participant CCO:B0023915 ! CAP1_HUMAN relationship: has_participant CCO:B0023918 ! CAP2_HUMAN relationship: has_participant CCO:B0023936 ! Q9BZ74_HUMAN relationship: has_participant CCO:B0023937 ! Q9H9L9_HUMAN relationship: has_participant CCO:B0024022 ! PAK2_HUMAN relationship: has_participant CCO:B0024303 ! Q4VBB4_HUMAN relationship: has_participant CCO:B0024306 ! PSYR_HUMAN relationship: has_participant CCO:B0024308 ! GPR4_HUMAN relationship: has_participant CCO:B0024398 ! RAP2B_HUMAN relationship: has_participant CCO:B0024404 ! RAP2A_HUMAN relationship: has_participant CCO:B0024481 ! Q6ZNQ9_HUMAN relationship: has_participant CCO:B0024484 ! PLCB3_HUMAN relationship: has_participant CCO:B0024486 ! Q8N1A4_HUMAN relationship: has_participant CCO:B0024595 ! Q2M2Z8_HUMAN relationship: has_participant CCO:B0024597 ! CEND3_HUMAN relationship: has_participant CCO:B0024600 ! CEND1_HUMAN relationship: has_participant CCO:B0024842 ! RARB_HUMAN relationship: has_participant CCO:B0024853 ! RARA_HUMAN relationship: has_participant CCO:B0024874 ! COT1_HUMAN relationship: has_participant CCO:B0024875 ! COT2_HUMAN relationship: has_participant CCO:B0024893 ! NR2F6_HUMAN relationship: has_participant CCO:B0025042 ! IL3RB_HUMAN relationship: has_participant CCO:B0025045 ! KPCB_HUMAN relationship: has_participant CCO:B0025046 ! KPCL_HUMAN relationship: has_participant CCO:B0025054 ! KPCE_HUMAN relationship: has_participant CCO:B0025098 ! LETM1_HUMAN relationship: has_participant CCO:B0025120 ! Q59FX3_HUMAN relationship: has_participant CCO:B0025184 ! IL6RB_HUMAN relationship: has_participant CCO:B0025401 ! MS4A7_HUMAN relationship: has_participant CCO:B0025403 ! A6NP53_HUMAN relationship: has_participant CCO:B0025802 ! RAC2_HUMAN relationship: has_participant CCO:B0025951 ! LRP5_HUMAN relationship: has_participant CCO:B0025990 ! 2A5B_HUMAN relationship: has_participant CCO:B0025993 ! Q59EK0_HUMAN relationship: has_participant CCO:B0025995 ! Q96B13_HUMAN relationship: has_participant CCO:B0025996 ! Q6ZN33_HUMAN relationship: has_participant CCO:B0026004 ! 2A5G_HUMAN relationship: has_participant CCO:B0026103 ! SORCN_HUMAN relationship: has_participant CCO:B0026109 ! Q8NEC4_HUMAN relationship: has_participant CCO:B0026111 ! 2ABD_HUMAN relationship: has_participant CCO:B0026113 ! Q59GC6_HUMAN relationship: has_participant CCO:B0026114 ! 2ABA_HUMAN relationship: has_participant CCO:B0026115 ! Q56VW8_HUMAN relationship: has_participant CCO:B0026116 ! 2ABB_HUMAN relationship: has_participant CCO:B0026117 ! Q6ZP32_HUMAN relationship: has_participant CCO:B0026121 ! 2ABG_HUMAN relationship: has_participant CCO:B0026125 ! A6NEJ2_HUMAN relationship: has_participant CCO:B0026530 ! NPAS2_HUMAN relationship: has_participant CCO:B0026531 ! CLOCK_HUMAN relationship: has_participant CCO:B0026532 ! Q53EU0_HUMAN relationship: has_participant CCO:B0026533 ! PASD1_HUMAN relationship: has_participant CCO:B0026534 ! A6NP27_HUMAN relationship: has_participant CCO:B0026602 ! P85B_HUMAN relationship: has_participant CCO:B0026606 ! Q05BV6_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0026617 ! A8K6J2_HUMAN relationship: has_participant CCO:B0026618 ! Q5JYS9_HUMAN relationship: has_participant CCO:B0026626 ! PECA1_HUMAN relationship: has_participant CCO:B0026726 ! MRGRF_HUMAN relationship: has_participant CCO:B0026768 ! MK10_HUMAN relationship: has_participant CCO:B0026846 ! CNTFR_HUMAN relationship: has_participant CCO:B0027081 ! GTF2I_HUMAN relationship: has_participant CCO:B0027165 ! CDKL2_HUMAN relationship: has_participant CCO:B0027200 ! FPR1_HUMAN relationship: has_participant CCO:B0027467 ! MCA1_HUMAN relationship: has_participant CCO:B0027476 ! A1E5M1_HUMAN relationship: has_participant CCO:B0027477 ! PDE7B_HUMAN relationship: has_participant CCO:B0027478 ! PDE7A_HUMAN relationship: has_participant CCO:B0027481 ! Q4VXJ0_HUMAN relationship: has_participant CCO:B0027486 ! Q96T72_HUMAN relationship: has_participant CCO:B0027493 ! TYRO3_HUMAN relationship: has_participant CCO:B0027548 ! Q5JWE9_HUMAN relationship: has_participant CCO:B0027550 ! GNAS2_HUMAN relationship: has_participant CCO:B0027551 ! GNAL_HUMAN relationship: has_participant CCO:B0027553 ! Q5FWY2_HUMAN relationship: has_participant CCO:B0027554 ! GNAS1_HUMAN relationship: has_participant CCO:B0027555 ! O60726_HUMAN relationship: has_participant CCO:B0027556 ! A6NI00_HUMAN relationship: has_participant CCO:B0027558 ! Q14455_HUMAN relationship: has_participant CCO:B0027562 ! Q86XU3_HUMAN relationship: has_participant CCO:B0027564 ! Q5JWE8_HUMAN relationship: has_participant CCO:B0027846 ! A8K4V1_HUMAN relationship: has_participant CCO:B0028201 ! OR1D2_HUMAN relationship: has_participant CCO:B0028205 ! Q6IFM2_HUMAN relationship: has_participant CCO:B0028206 ! Q6IFL7_HUMAN relationship: has_participant CCO:B0028291 ! DLL4_HUMAN relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0028618 ! KS6A3_HUMAN relationship: has_participant CCO:B0028620 ! KS6A6_HUMAN relationship: has_participant CCO:B0028627 ! KS6A1_HUMAN relationship: has_participant CCO:B0028628 ! Q7Z721_HUMAN relationship: has_participant CCO:B0028633 ! KS6B1_HUMAN relationship: has_participant CCO:B0028634 ! KS6A2_HUMAN relationship: has_participant CCO:B0028910 ! Q9NWJ6_HUMAN relationship: has_participant CCO:B0028914 ! AB1IP_HUMAN relationship: has_participant CCO:B0029013 ! OR9I1_HUMAN relationship: has_participant CCO:B0029014 ! Q6IF62_HUMAN relationship: has_participant CCO:B0029015 ! OR5W2_HUMAN relationship: has_participant CCO:B0029017 ! OR5B3_HUMAN relationship: has_participant CCO:B0029019 ! Q8NH91_HUMAN relationship: has_participant CCO:B0029022 ! OR8K5_HUMAN relationship: has_participant CCO:B0029023 ! OR5L1_HUMAN relationship: has_participant CCO:B0029024 ! OR5B2_HUMAN relationship: has_participant CCO:B0029025 ! OR8U1_HUMAN relationship: has_participant CCO:B0029027 ! A8MUX1_HUMAN relationship: has_participant CCO:B0029028 ! OR5BC_HUMAN relationship: has_participant CCO:B0029029 ! OR5R1_HUMAN relationship: has_participant CCO:B0029030 ! OR5C1_HUMAN relationship: has_participant CCO:B0029031 ! OR8G5_HUMAN relationship: has_participant CCO:B0029032 ! Q6IEU2_HUMAN relationship: has_participant CCO:B0029033 ! OR5J2_HUMAN relationship: has_participant CCO:B0029034 ! OR8D4_HUMAN relationship: has_participant CCO:B0029035 ! O5AR1_HUMAN relationship: has_participant CCO:B0029036 ! Q6IFM9_HUMAN relationship: has_participant CCO:B0029037 ! A8MXK6_HUMAN relationship: has_participant CCO:B0029038 ! O5AS1_HUMAN relationship: has_participant CCO:B0029039 ! OR5BH_HUMAN relationship: has_participant CCO:B0029040 ! OR5L2_HUMAN relationship: has_participant CCO:B0029082 ! ROS_HUMAN relationship: has_participant CCO:B0029136 ! A8MZB4_HUMAN relationship: has_participant CCO:B0029137 ! A8MU22_HUMAN relationship: has_participant CCO:B0029138 ! A8KAK0_HUMAN relationship: has_participant CCO:B0029139 ! A8MSY7_HUMAN relationship: has_participant CCO:B0029141 ! A8MW32_HUMAN relationship: has_participant CCO:B0029277 ! MKLN1_HUMAN relationship: has_participant CCO:B0029683 ! Q56TK0_HUMAN relationship: has_participant CCO:B0029685 ! STAT6_HUMAN relationship: has_participant CCO:B0029695 ! CEAM6_HUMAN relationship: has_participant CCO:B0029881 ! O15302_HUMAN relationship: has_participant CCO:B0030075 ! A8MTR7_HUMAN relationship: has_participant CCO:B0030164 ! TLR1_HUMAN relationship: has_participant CCO:B0030165 ! TLR10_HUMAN relationship: has_participant CCO:B0030167 ! Q2NKL3_HUMAN relationship: has_participant CCO:B0030171 ! TLR2_HUMAN relationship: has_participant CCO:B0030172 ! TLR6_HUMAN relationship: has_participant CCO:B0030243 ! Q6NT27_HUMAN relationship: has_participant CCO:B0030249 ! GNAZ_HUMAN relationship: has_participant CCO:B0030251 ! GNA11_HUMAN relationship: has_participant CCO:B0030261 ! GNA14_HUMAN relationship: has_participant CCO:B0030262 ! GNAT2_HUMAN relationship: has_participant CCO:B0030265 ! Q6B6N3_HUMAN relationship: has_participant CCO:B0030266 ! GNAT1_HUMAN relationship: has_participant CCO:B0030269 ! GNAI3_HUMAN relationship: has_participant CCO:B0030280 ! RND2_HUMAN relationship: has_participant CCO:B0030552 ! MC3R_HUMAN relationship: has_participant CCO:B0030561 ! MSHR_HUMAN relationship: has_participant CCO:B0030569 ! MC5R_HUMAN relationship: has_participant CCO:B0030574 ! MC4R_HUMAN relationship: has_participant CCO:B0030577 ! ACTHR_HUMAN relationship: has_participant CCO:B0030604 ! A8K7W5_HUMAN relationship: has_participant CCO:B0030651 ! AMHR2_HUMAN relationship: has_participant CCO:B0030742 ! IDE_HUMAN relationship: has_participant CCO:B0030750 ! CSN3_HUMAN relationship: has_participant CCO:B0030838 ! OPTN_HUMAN relationship: has_participant CCO:B0031064 ! LIMD1_HUMAN relationship: has_participant CCO:B0031117 ! Q4LE74_HUMAN relationship: has_participant CCO:B0031122 ! MYO9B_HUMAN relationship: has_participant CCO:B0031540 ! APC2_HUMAN relationship: has_participant CCO:B0031607 ! TA2R5_HUMAN relationship: has_participant CCO:B0031630 ! LIPA1_HUMAN relationship: has_participant CCO:B0032345 ! Q5Y190_HUMAN relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0032797 ! ACHB4_HUMAN relationship: has_participant CCO:B0032798 ! ACHA6_HUMAN relationship: has_participant CCO:B0032799 ! ACHB3_HUMAN relationship: has_participant CCO:B0032804 ! ACHA3_HUMAN relationship: has_participant CCO:B0032806 ! ACHA5_HUMAN relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN relationship: has_participant CCO:B0032809 ! ACHA2_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN relationship: has_participant CCO:B0033173 ! Q59FU8_HUMAN relationship: has_participant CCO:B0033174 ! Q5T9P3_HUMAN relationship: has_participant CCO:B0033252 ! OPSX_HUMAN relationship: has_participant CCO:B0033253 ! A6NEB4_HUMAN relationship: has_participant CCO:B0033254 ! OPN4_HUMAN relationship: has_participant CCO:B0033323 ! RGS12_HUMAN relationship: has_participant CCO:B0033332 ! RGS14_HUMAN relationship: has_participant CCO:B0033334 ! Q147X0_HUMAN relationship: has_participant CCO:B0033335 ! Q6IFC7_HUMAN relationship: has_participant CCO:B0033337 ! A8MTX1_HUMAN relationship: has_participant CCO:B0033338 ! OR5T1_HUMAN relationship: has_participant CCO:B0033339 ! A8MW53_HUMAN relationship: has_participant CCO:B0033340 ! O5AK3_HUMAN relationship: has_participant CCO:B0033341 ! OR5K4_HUMAN relationship: has_participant CCO:B0033342 ! A8MWJ9_HUMAN relationship: has_participant CCO:B0033343 ! Q6IFC8_HUMAN relationship: has_participant CCO:B0033344 ! OR9Q2_HUMAN relationship: has_participant CCO:B0033345 ! A8MXY9_HUMAN relationship: has_participant CCO:B0033346 ! OR5I1_HUMAN relationship: has_participant CCO:B0033347 ! O5AC1_HUMAN relationship: has_participant CCO:B0033348 ! A8MVK2_HUMAN relationship: has_participant CCO:B0033349 ! O5H14_HUMAN relationship: has_participant CCO:B0033351 ! Q8IXE7_HUMAN relationship: has_participant CCO:B0033405 ! GP126_HUMAN relationship: has_participant CCO:B0033412 ! GP112_HUMAN relationship: has_participant CCO:B0033418 ! GPR64_HUMAN relationship: has_participant CCO:B0033433 ! NMDE4_HUMAN relationship: has_participant CCO:B0033477 ! LRP8_HUMAN relationship: has_participant CCO:B0033592 ! PPIC_HUMAN relationship: has_participant CCO:B0033903 ! CENB1_HUMAN relationship: has_participant CCO:B0034076 ! RABP1_HUMAN relationship: has_participant CCO:B0034094 ! RHG28_HUMAN relationship: has_participant CCO:B0034095 ! A8MQB7_HUMAN relationship: has_participant CCO:B0034099 ! A8MU88_HUMAN relationship: has_participant CCO:B0034172 ! A9UF07_HUMAN relationship: has_participant CCO:B0034175 ! A9UF02_HUMAN relationship: has_participant CCO:B0034258 ! GAS6_HUMAN relationship: has_participant CCO:B0035939 ! C8AP2_HUMAN relationship: has_participant CCO:B0036109 ! CO3_HUMAN relationship: has_participant CCO:B0036515 ! Q14CQ7_HUMAN relationship: has_participant CCO:B0036527 ! Q5T8F1_HUMAN relationship: has_participant CCO:B0036594 ! NKG2C_HUMAN relationship: has_participant CCO:B0036631 ! LRRN2_HUMAN relationship: has_participant CCO:B0037083 ! RXFP2_HUMAN relationship: has_participant CCO:B0037085 ! RXFP1_HUMAN relationship: has_participant CCO:B0037087 ! Q3KU23_HUMAN relationship: has_participant CCO:B0037229 ! PE2R3_HUMAN relationship: has_participant CCO:B0037300 ! RRBP1_HUMAN relationship: has_participant CCO:B0037521 ! RAGP1_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN relationship: has_participant CCO:B0038258 ! ADA1A_HUMAN relationship: has_participant CCO:B0038260 ! 5HT2C_HUMAN relationship: has_participant CCO:B0038261 ! Q7Z5R9_HUMAN relationship: has_participant CCO:B0038262 ! HRH2_HUMAN relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN relationship: has_participant CCO:B0038265 ! ADA1D_HUMAN relationship: has_participant CCO:B0038266 ! 5HT1D_HUMAN relationship: has_participant CCO:B0038267 ! ADA2B_HUMAN relationship: has_participant CCO:B0038385 ! RPGF1_HUMAN relationship: has_participant CCO:B0038590 ! Q6IFJ9_HUMAN relationship: has_participant CCO:B0038591 ! Q8NG79_HUMAN relationship: has_participant CCO:B0038592 ! OR6M1_HUMAN relationship: has_participant CCO:B0038594 ! A6NJJ1_HUMAN relationship: has_participant CCO:B0038671 ! REL1_HUMAN relationship: has_participant CCO:B0038854 ! FZD5_HUMAN relationship: has_participant CCO:B0038855 ! FZD1_HUMAN relationship: has_participant CCO:B0038856 ! FZD7_HUMAN relationship: has_participant CCO:B0038857 ! FZD2_HUMAN relationship: has_participant CCO:B0038861 ! FZD9_HUMAN relationship: has_participant CCO:B0038863 ! FZD8_HUMAN relationship: has_participant CCO:B0038865 ! FZD10_HUMAN relationship: has_participant CCO:B0038963 ! CCL7_HUMAN relationship: has_participant CCO:B0038965 ! CCL2_HUMAN relationship: has_participant CCO:B0038966 ! CCL13_HUMAN relationship: has_participant CCO:B0038969 ! CCL11_HUMAN relationship: has_participant CCO:B0038971 ! CCL8_HUMAN relationship: has_participant CCO:B0039174 ! MTSSL_HUMAN relationship: has_participant CCO:B0039239 ! GBRB1_HUMAN relationship: has_participant CCO:B0039240 ! GBRB3_HUMAN relationship: has_participant CCO:B0039886 ! RHEB_HUMAN relationship: has_participant CCO:B0039945 ! CRBL2_HUMAN relationship: has_participant CCO:B0040141 ! B0I1T6_HUMAN relationship: has_participant CCO:B0040467 ! CASP1_HUMAN relationship: has_participant CCO:B0041368 ! RHG27_HUMAN relationship: has_participant CCO:B0041371 ! RHG15_HUMAN relationship: has_participant CCO:B0041373 ! Q1RLN5_HUMAN relationship: has_participant CCO:B0041376 ! RHG12_HUMAN relationship: has_participant CCO:B0041417 ! FLNB_HUMAN relationship: has_participant CCO:B0041421 ! STAR8_HUMAN relationship: has_participant CCO:B0041474 ! B1AHC4_HUMAN relationship: has_participant CCO:B0041516 ! ANK2_HUMAN relationship: has_participant CCO:B0041521 ! Q7Z3L5_HUMAN relationship: has_participant CCO:B0041523 ! ANK1_HUMAN relationship: has_participant CCO:B0041526 ! ANK3_HUMAN relationship: has_participant CCO:B0041528 ! Q7Z3G4_HUMAN relationship: has_participant CCO:B0041531 ! Q5CZH9_HUMAN relationship: has_participant CCO:B0041532 ! B1AQT2_HUMAN relationship: has_participant CCO:B0041666 ! CXCL5_HUMAN relationship: has_participant CCO:B0041668 ! GROA_HUMAN relationship: has_participant CCO:B0041670 ! CXCL6_HUMAN relationship: has_participant CCO:B0041822 ! CAN5_HUMAN relationship: has_participant CCO:B0041921 ! B0UXY8_HUMAN relationship: has_participant CCO:B0041922 ! GABR2_HUMAN relationship: has_participant CCO:B0041924 ! Q8NHA5_HUMAN relationship: has_participant CCO:B0041925 ! B0UXY7_HUMAN relationship: has_participant CCO:B0041927 ! A6NNW8_HUMAN relationship: has_participant CCO:B0042031 ! PDIA3_HUMAN relationship: has_participant CCO:B0042222 ! GRM3_HUMAN relationship: has_participant CCO:B0042225 ! GRM4_HUMAN relationship: has_participant CCO:B0042226 ! Q8N0Z0_HUMAN relationship: has_participant CCO:B0042227 ! GRM7_HUMAN relationship: has_participant CCO:B0042228 ! A4D0Y3_HUMAN relationship: has_participant CCO:B0042229 ! Q8NHA9_HUMAN relationship: has_participant CCO:B0042230 ! GRM5_HUMAN relationship: has_participant CCO:B0042237 ! Q86YG3_HUMAN relationship: has_participant CCO:B0042238 ! Q6J164_HUMAN relationship: has_participant CCO:B0042239 ! GRM2_HUMAN relationship: has_participant CCO:B0042241 ! GRM8_HUMAN relationship: has_participant CCO:B0042244 ! GRM6_HUMAN relationship: has_participant CCO:B0042245 ! GRM1_HUMAN relationship: has_participant CCO:B0042246 ! A8K1R9_HUMAN relationship: has_participant CCO:B0042251 ! Q6ZMQ2_HUMAN relationship: has_participant CCO:B0042255 ! Q59HC2_HUMAN relationship: has_participant CCO:B0042283 ! IMPA2_HUMAN relationship: has_participant CCO:B0042291 ! IMPA1_HUMAN relationship: has_participant CCO:B0042293 ! ACHG_HUMAN relationship: has_participant CCO:B0042294 ! ACHE_HUMAN relationship: has_participant CCO:B0042408 ! HIF3A_HUMAN relationship: has_participant CCO:B0042415 ! A8MYV6_HUMAN relationship: has_participant CCO:B0042416 ! A8MPQ1_HUMAN relationship: has_participant CCO:B0042545 ! B1AL79_HUMAN relationship: has_participant CCO:B0042813 ! IL2RB_HUMAN relationship: has_participant CCO:B0042824 ! FCGR1_HUMAN relationship: has_participant CCO:B0043423 ! RASF8_HUMAN relationship: has_participant CCO:B0043425 ! IP3KB_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN relationship: has_participant CCO:B0043552 ! PI51A_HUMAN relationship: has_participant CCO:B0043823 ! EDN3_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN relationship: has_participant CCO:B0043867 ! LPAR4_HUMAN relationship: has_participant CCO:B0048872 ! ALS_HUMAN relationship: has_participant CCO:B0049157 ! PAR4_HUMAN relationship: has_participant CCO:B0049161 ! PAR2_HUMAN relationship: has_participant CCO:B0049379 ! GNAT3_HUMAN relationship: has_participant CCO:B0049381 ! GNAO_HUMAN relationship: has_participant CCO:B0049425 ! CNTF_HUMAN relationship: has_participant CCO:B0049439 ! RYR2_HUMAN relationship: has_participant CCO:B0049448 ! Q53TQ2_HUMAN relationship: has_participant CCO:B0049452 ! NK2R_HUMAN relationship: has_participant CCO:B0049455 ! NK3R_HUMAN relationship: has_participant CCO:B0049457 ! NK1R_HUMAN relationship: has_participant CCO:B0049558 ! HG2A_HUMAN relationship: has_participant CCO:B0049806 ! OR8H1_HUMAN relationship: has_participant CCO:B0049809 ! A8MYY4_HUMAN relationship: has_participant CCO:B0049812 ! A8MYM5_HUMAN relationship: has_participant CCO:B0049813 ! OR8B4_HUMAN relationship: has_participant CCO:B0049814 ! OR8H3_HUMAN relationship: has_participant CCO:B0049816 ! OR8H2_HUMAN relationship: has_participant CCO:B0049817 ! OR5MB_HUMAN relationship: has_participant CCO:B0049905 ! Q24JP0_HUMAN relationship: has_participant CCO:B0050202 ! ITAL_HUMAN relationship: has_participant CCO:B0050216 ! A7MBN2_HUMAN relationship: has_participant CCO:B0050218 ! TENA_HUMAN relationship: has_participant CCO:B0050242 ! MP2K5_HUMAN relationship: has_participant CCO:B0050348 ! AHRR_HUMAN relationship: has_participant CCO:B0050528 ! CNOT7_HUMAN relationship: has_participant CCO:B0050581 ! IPO8_HUMAN relationship: has_participant CCO:B0050753 ! OPRD_HUMAN relationship: has_participant CCO:B0050755 ! SSR2_HUMAN relationship: has_participant CCO:B0050756 ! Q9H573_HUMAN relationship: has_participant CCO:B0050758 ! OPRK_HUMAN relationship: has_participant CCO:B0050760 ! A6NL10_HUMAN relationship: has_participant CCO:B0050761 ! Q8IXB0_HUMAN relationship: has_participant CCO:B0050764 ! NPBW2_HUMAN relationship: has_participant CCO:B0050772 ! Q8IWW3_HUMAN relationship: has_participant CCO:B0050781 ! OPRX_HUMAN relationship: has_participant CCO:B0050782 ! NPBW1_HUMAN relationship: has_participant CCO:B0050784 ! Q8IWP3_HUMAN relationship: has_participant CCO:B0050785 ! SSR5_HUMAN relationship: has_participant CCO:B0050788 ! SSR1_HUMAN relationship: has_participant CCO:B0050791 ! Q5TBX0_HUMAN relationship: has_participant CCO:B0050792 ! Q8IWW4_HUMAN relationship: has_participant CCO:B0050793 ! SSR4_HUMAN relationship: has_participant CCO:B0050794 ! SSR3_HUMAN relationship: has_participant CCO:B0051400 ! YS018_HUMAN relationship: has_participant CCO:B0051401 ! B1AKC7_HUMAN relationship: has_participant CCO:B0051810 ! IRS1_HUMAN relationship: has_participant CCO:B0051815 ! IRS4_HUMAN relationship: has_participant CCO:B0051877 ! OR8D2_HUMAN relationship: has_participant CCO:B0051880 ! OR8G1_HUMAN relationship: has_participant CCO:B0051882 ! OR8G2_HUMAN relationship: has_participant CCO:B0051883 ! OR8U9_HUMAN relationship: has_participant CCO:B0051887 ! O5AK2_HUMAN relationship: has_participant CCO:B0051892 ! OR8U8_HUMAN relationship: has_participant CCO:B0051893 ! O5AP2_HUMAN relationship: has_participant CCO:B0053696 ! A0A502_HUMAN relationship: has_participant CCO:B0053698 ! A0AVG4_HUMAN relationship: has_participant CCO:B0053701 ! A0JLR9_HUMAN relationship: has_participant CCO:B0053705 ! RHG10_HUMAN relationship: has_participant CCO:B0053706 ! A1A4T0_HUMAN relationship: has_participant CCO:B0053714 ! A2A284_HUMAN relationship: has_participant CCO:B0053724 ! A2BDZ0_HUMAN relationship: has_participant CCO:B0053725 ! A2BDZ2_HUMAN relationship: has_participant CCO:B0053726 ! A2BEC2_HUMAN relationship: has_participant CCO:B0053727 ! A2BF33_HUMAN relationship: has_participant CCO:B0053728 ! A2BF34_HUMAN relationship: has_participant CCO:B0053730 ! A2I2N6_HUMAN relationship: has_participant CCO:B0053738 ! A2RTX9_HUMAN relationship: has_participant CCO:B0053739 ! A2RU51_HUMAN relationship: has_participant CCO:B0053742 ! OR2M5_HUMAN relationship: has_participant CCO:B0053747 ! A3KN82_HUMAN relationship: has_participant CCO:B0053751 ! YG015_HUMAN relationship: has_participant CCO:B0053755 ! A4D258_HUMAN relationship: has_participant CCO:B0053758 ! A4D2G2_HUMAN relationship: has_participant CCO:B0053759 ! O2A25_HUMAN relationship: has_participant CCO:B0053764 ! A4FU63_HUMAN relationship: has_participant CCO:B0053783 ! A6NC31_HUMAN relationship: has_participant CCO:B0053784 ! A6NC89_HUMAN relationship: has_participant CCO:B0053786 ! O6C74_HUMAN relationship: has_participant CCO:B0053788 ! O14I1_HUMAN relationship: has_participant CCO:B0053790 ! A6NDI7_HUMAN relationship: has_participant CCO:B0053793 ! O6C68_HUMAN relationship: has_participant CCO:B0053800 ! A6NE11_HUMAN relationship: has_participant CCO:B0053805 ! A6NE96_HUMAN relationship: has_participant CCO:B0053806 ! A6NEC7_HUMAN relationship: has_participant CCO:B0053816 ! OR6C6_HUMAN relationship: has_participant CCO:B0053817 ! OR2W5_HUMAN relationship: has_participant CCO:B0053824 ! A6NFR0_HUMAN relationship: has_participant CCO:B0053834 ! A6NGT9_HUMAN relationship: has_participant CCO:B0053835 ! O51F1_HUMAN relationship: has_participant CCO:B0053836 ! OR2T8_HUMAN relationship: has_participant CCO:B0053842 ! A6NH69_HUMAN relationship: has_participant CCO:B0053845 ! O4C46_HUMAN relationship: has_participant CCO:B0053847 ! A6NHG8_HUMAN relationship: has_participant CCO:B0053852 ! A6NHV0_HUMAN relationship: has_participant CCO:B0053854 ! YE015_HUMAN relationship: has_participant CCO:B0053857 ! RH10L_HUMAN relationship: has_participant CCO:B0053861 ! A6NIH4_HUMAN relationship: has_participant CCO:B0053862 ! O6C70_HUMAN relationship: has_participant CCO:B0053863 ! A6NIQ0_HUMAN relationship: has_participant CCO:B0053866 ! A6NJ05_HUMAN relationship: has_participant CCO:B0053868 ! A6NJ38_HUMAN relationship: has_participant CCO:B0053872 ! A6NJJ3_HUMAN relationship: has_participant CCO:B0053875 ! O6C65_HUMAN relationship: has_participant CCO:B0053880 ! RASFA_HUMAN relationship: has_participant CCO:B0053886 ! A6NKK7_HUMAN relationship: has_participant CCO:B0053887 ! A6NKM1_HUMAN relationship: has_participant CCO:B0053890 ! O6C75_HUMAN relationship: has_participant CCO:B0053892 ! OR5BL_HUMAN relationship: has_participant CCO:B0053893 ! A6NL96_HUMAN relationship: has_participant CCO:B0053902 ! O2AG2_HUMAN relationship: has_participant CCO:B0053904 ! O6C76_HUMAN relationship: has_participant CCO:B0053908 ! O52A4_HUMAN relationship: has_participant CCO:B0053909 ! A6NMV7_HUMAN relationship: has_participant CCO:B0053910 ! O4C45_HUMAN relationship: has_participant CCO:B0053911 ! A6NN09_HUMAN relationship: has_participant CCO:B0053914 ! O2AT4_HUMAN relationship: has_participant CCO:B0053916 ! A6NNH7_HUMAN relationship: has_participant CCO:B0053920 ! YA036_HUMAN relationship: has_participant CCO:B0053935 ! A6PVX5_HUMAN relationship: has_participant CCO:B0053938 ! A6QRG9_HUMAN relationship: has_participant CCO:B0053939 ! A6QRH2_HUMAN relationship: has_participant CCO:B0053941 ! A6YCE1_HUMAN relationship: has_participant CCO:B0053942 ! A6YCE2_HUMAN relationship: has_participant CCO:B0053943 ! A6ZJ79_HUMAN relationship: has_participant CCO:B0053947 ! RICS_HUMAN relationship: has_participant CCO:B0053957 ! A8K2J1_HUMAN relationship: has_participant CCO:B0053958 ! A8K2Y1_HUMAN relationship: has_participant CCO:B0053960 ! A8K305_HUMAN relationship: has_participant CCO:B0053967 ! A8K4X3_HUMAN relationship: has_participant CCO:B0053977 ! A8K7K1_HUMAN relationship: has_participant CCO:B0053980 ! A8K8M5_HUMAN relationship: has_participant CCO:B0053982 ! A8K9D9_HUMAN relationship: has_participant CCO:B0053987 ! A8MPQ3_HUMAN relationship: has_participant CCO:B0053988 ! A8MPS8_HUMAN relationship: has_participant CCO:B0053998 ! A8MQB2_HUMAN relationship: has_participant CCO:B0053999 ! A8MQT8_HUMAN relationship: has_participant CCO:B0054004 ! A8MS86_HUMAN relationship: has_participant CCO:B0054007 ! A8MSJ7_HUMAN relationship: has_participant CCO:B0054008 ! A8MSL1_HUMAN relationship: has_participant CCO:B0054015 ! A8MSW6_HUMAN relationship: has_participant CCO:B0054018 ! A8MSZ9_HUMAN relationship: has_participant CCO:B0054020 ! A8MT47_HUMAN relationship: has_participant CCO:B0054024 ! A8MTE1_HUMAN relationship: has_participant CCO:B0054027 ! A8MTI0_HUMAN relationship: has_participant CCO:B0054032 ! A8MTP8_HUMAN relationship: has_participant CCO:B0054037 ! A8MU07_HUMAN relationship: has_participant CCO:B0054038 ! A8MU91_HUMAN relationship: has_participant CCO:B0054039 ! A8MUF8_HUMAN relationship: has_participant CCO:B0054042 ! A8MUM9_HUMAN relationship: has_participant CCO:B0054044 ! BCRL2_HUMAN relationship: has_participant CCO:B0054045 ! A8MUS4_HUMAN relationship: has_participant CCO:B0054049 ! A8MUW4_HUMAN relationship: has_participant CCO:B0054050 ! A8MUY8_HUMAN relationship: has_participant CCO:B0054052 ! A8MV06_HUMAN relationship: has_participant CCO:B0054058 ! A8MVF0_HUMAN relationship: has_participant CCO:B0054060 ! A8MVM2_HUMAN relationship: has_participant CCO:B0054061 ! A8MVM5_HUMAN relationship: has_participant CCO:B0054066 ! A8MVV5_HUMAN relationship: has_participant CCO:B0054073 ! A8MW54_HUMAN relationship: has_participant CCO:B0054079 ! A8MWG5_HUMAN relationship: has_participant CCO:B0054080 ! A8MWI1_HUMAN relationship: has_participant CCO:B0054086 ! A8MX01_HUMAN relationship: has_participant CCO:B0054091 ! A8MX59_HUMAN relationship: has_participant CCO:B0054093 ! A8MX88_HUMAN relationship: has_participant CCO:B0054094 ! A8MXA6_HUMAN relationship: has_participant CCO:B0054095 ! A8MXE9_HUMAN relationship: has_participant CCO:B0054097 ! A8MXI2_HUMAN relationship: has_participant CCO:B0054100 ! A8MXL5_HUMAN relationship: has_participant CCO:B0054104 ! A8MXU4_HUMAN relationship: has_participant CCO:B0054105 ! A8MXV8_HUMAN relationship: has_participant CCO:B0054108 ! A8MXZ2_HUMAN relationship: has_participant CCO:B0054109 ! A8MXZ4_HUMAN relationship: has_participant CCO:B0054111 ! A8MY27_HUMAN relationship: has_participant CCO:B0054114 ! A8MY69_HUMAN relationship: has_participant CCO:B0054116 ! A8MY83_HUMAN relationship: has_participant CCO:B0054117 ! A8MY84_HUMAN relationship: has_participant CCO:B0054135 ! A8MZ16_HUMAN relationship: has_participant CCO:B0054138 ! A8MZD7_HUMAN relationship: has_participant CCO:B0054142 ! A8MZG7_HUMAN relationship: has_participant CCO:B0054152 ! A9UF01_HUMAN relationship: has_participant CCO:B0054153 ! A9UF05_HUMAN relationship: has_participant CCO:B0054155 ! A9UJY7_HUMAN relationship: has_participant CCO:B0054162 ! B0AZW0_HUMAN relationship: has_participant CCO:B0054179 ! B0QZ65_HUMAN relationship: has_participant CCO:B0054180 ! B0QZ66_HUMAN relationship: has_participant CCO:B0054181 ! B0QZ67_HUMAN relationship: has_participant CCO:B0054182 ! B0QZD1_HUMAN relationship: has_participant CCO:B0054186 ! B0UY34_HUMAN relationship: has_participant CCO:B0054187 ! B0UYX3_HUMAN relationship: has_participant CCO:B0054188 ! B0V046_HUMAN relationship: has_participant CCO:B0054189 ! B0V1T2_HUMAN relationship: has_participant CCO:B0054190 ! B0V1T3_HUMAN relationship: has_participant CCO:B0054197 ! B0YJ91_HUMAN relationship: has_participant CCO:B0054198 ! B0ZBD2_HUMAN relationship: has_participant CCO:B0054199 ! B0ZBD3_HUMAN relationship: has_participant CCO:B0054200 ! B0ZBD8_HUMAN relationship: has_participant CCO:B0054210 ! B1AHB8_HUMAN relationship: has_participant CCO:B0054211 ! B1AHC3_HUMAN relationship: has_participant CCO:B0054241 ! B1ALU1_HUMAN relationship: has_participant CCO:B0054242 ! B1ALU2_HUMAN relationship: has_participant CCO:B0054243 ! B1ALU3_HUMAN relationship: has_participant CCO:B0054244 ! B1ALU4_HUMAN relationship: has_participant CCO:B0054245 ! B1ALU5_HUMAN relationship: has_participant CCO:B0054247 ! B1ALX0_HUMAN relationship: has_participant CCO:B0054249 ! B1AM21_HUMAN relationship: has_participant CCO:B0054251 ! B1AMA2_HUMAN relationship: has_participant CCO:B0054258 ! B1AMX9_HUMAN relationship: has_participant CCO:B0054268 ! B1AP63_HUMAN relationship: has_participant CCO:B0054283 ! B1B1F0_HUMAN relationship: has_participant CCO:B0054287 ! B1NLD0_HUMAN relationship: has_participant CCO:B0054291 ! GPR25_HUMAN relationship: has_participant CCO:B0054295 ! CCL24_HUMAN relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0054302 ! SIRB1_HUMAN relationship: has_participant CCO:B0054306 ! GPR31_HUMAN relationship: has_participant CCO:B0054309 ! CLIC1_HUMAN relationship: has_participant CCO:B0054310 ! TR11B_HUMAN relationship: has_participant CCO:B0054311 ! BMAL1_HUMAN relationship: has_participant CCO:B0054316 ! P2Y10_HUMAN relationship: has_participant CCO:B0054317 ! PDE2A_HUMAN relationship: has_participant CCO:B0054318 ! CCRL2_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN relationship: has_participant CCO:B0054333 ! CXCR6_HUMAN relationship: has_participant CCO:B0054334 ! CCL21_HUMAN relationship: has_participant CCO:B0054335 ! CCBP2_HUMAN relationship: has_participant CCO:B0054338 ! CCL22_HUMAN relationship: has_participant CCO:B0054340 ! WN10B_HUMAN relationship: has_participant CCO:B0054341 ! WNT7A_HUMAN relationship: has_participant CCO:B0054343 ! SH2B2_HUMAN relationship: has_participant CCO:B0054346 ! NRG2_HUMAN relationship: has_participant CCO:B0054348 ! BAI1_HUMAN relationship: has_participant CCO:B0054352 ! TCGAP_HUMAN relationship: has_participant CCO:B0054353 ! OR7AH_HUMAN relationship: has_participant CCO:B0054356 ! GBGT2_HUMAN relationship: has_participant CCO:B0054359 ! CXL11_HUMAN relationship: has_participant CCO:B0054360 ! GP171_HUMAN relationship: has_participant CCO:B0054363 ! DVL1_HUMAN relationship: has_participant CCO:B0054367 ! PTGES_HUMAN relationship: has_participant CCO:B0054368 ! O14694_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0054377 ! UN13B_HUMAN relationship: has_participant CCO:B0054378 ! TAAR5_HUMAN relationship: has_participant CCO:B0054382 ! FFAR1_HUMAN relationship: has_participant CCO:B0054383 ! FFAR3_HUMAN relationship: has_participant CCO:B0054385 ! BCKD_HUMAN relationship: has_participant CCO:B0054386 ! MGST3_HUMAN relationship: has_participant CCO:B0054400 ! PER2_HUMAN relationship: has_participant CCO:B0054407 ! FYB_HUMAN relationship: has_participant CCO:B0054408 ! ANGP2_HUMAN relationship: has_participant CCO:B0054413 ! BRAC_HUMAN relationship: has_participant CCO:B0054416 ! RGL2_HUMAN relationship: has_participant CCO:B0054417 ! GP182_HUMAN relationship: has_participant CCO:B0054419 ! CLIC2_HUMAN relationship: has_participant CCO:B0054420 ! NPHP1_HUMAN relationship: has_participant CCO:B0054429 ! INP4B_HUMAN relationship: has_participant CCO:B0054432 ! GPR37_HUMAN relationship: has_participant CCO:B0054434 ! O15376_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0054444 ! GPR42_HUMAN relationship: has_participant CCO:B0054445 ! PER1_HUMAN relationship: has_participant CCO:B0054447 ! P2RX6_HUMAN relationship: has_participant CCO:B0054448 ! FFAR2_HUMAN relationship: has_participant CCO:B0054451 ! PLXB1_HUMAN relationship: has_participant CCO:B0054455 ! RHG06_HUMAN relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0054458 ! O43192_HUMAN relationship: has_participant CCO:B0054459 ! MTLR_HUMAN relationship: has_participant CCO:B0054460 ! GPR39_HUMAN relationship: has_participant CCO:B0054466 ! SRGP2_HUMAN relationship: has_participant CCO:B0054478 ! RASL2_HUMAN relationship: has_participant CCO:B0054479 ! O43392_HUMAN relationship: has_participant CCO:B0054480 ! P52K_HUMAN relationship: has_participant CCO:B0054484 ! TNF12_HUMAN relationship: has_participant CCO:B0054487 ! O43535_HUMAN relationship: has_participant CCO:B0054489 ! GON2_HUMAN relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0054491 ! FRS3_HUMAN relationship: has_participant CCO:B0054492 ! LAT_HUMAN relationship: has_participant CCO:B0054493 ! AKA10_HUMAN relationship: has_participant CCO:B0054498 ! GALR2_HUMAN relationship: has_participant CCO:B0054502 ! OX1R_HUMAN relationship: has_participant CCO:B0054503 ! OX2R_HUMAN relationship: has_participant CCO:B0054505 ! O43627_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0054507 ! O43649_HUMAN relationship: has_participant CCO:B0054517 ! AAKB2_HUMAN relationship: has_participant CCO:B0054518 ! OR1F1_HUMAN relationship: has_participant CCO:B0054522 ! ANGL7_HUMAN relationship: has_participant CCO:B0054527 ! O43851_HUMAN relationship: has_participant CCO:B0054528 ! OR2T1_HUMAN relationship: has_participant CCO:B0054530 ! TYOBP_HUMAN relationship: has_participant CCO:B0054534 ! KALRN_HUMAN relationship: has_participant CCO:B0054535 ! MYPT2_HUMAN relationship: has_participant CCO:B0054536 ! BAI3_HUMAN relationship: has_participant CCO:B0054537 ! GBG7_HUMAN relationship: has_participant CCO:B0054549 ! FZD6_HUMAN relationship: has_participant CCO:B0054552 ! O10H2_HUMAN relationship: has_participant CCO:B0054553 ! O10H3_HUMAN relationship: has_participant CCO:B0054554 ! O60411_HUMAN relationship: has_participant CCO:B0054555 ! OR7C2_HUMAN relationship: has_participant CCO:B0054558 ! OR1I1_HUMAN relationship: has_participant CCO:B0054559 ! O60432_HUMAN relationship: has_participant CCO:B0054560 ! O60466_HUMAN relationship: has_participant CCO:B0054561 ! PLXC1_HUMAN relationship: has_participant CCO:B0054562 ! DOK2_HUMAN relationship: has_participant CCO:B0054563 ! ADCY9_HUMAN relationship: has_participant CCO:B0054569 ! TLR5_HUMAN relationship: has_participant CCO:B0054570 ! GFRA3_HUMAN relationship: has_participant CCO:B0054571 ! PDE8A_HUMAN relationship: has_participant CCO:B0054576 ! GALR3_HUMAN relationship: has_participant CCO:B0054578 ! PTGD2_HUMAN relationship: has_participant CCO:B0054585 ! ETBR2_HUMAN relationship: has_participant CCO:B0054586 ! OPHN1_HUMAN relationship: has_participant CCO:B0054590 ! TBL1X_HUMAN relationship: has_participant CCO:B0054596 ! PLCH2_HUMAN relationship: has_participant CCO:B0054598 ! FNBP2_HUMAN relationship: has_participant CCO:B0054599 ! PLXA2_HUMAN relationship: has_participant CCO:B0054600 ! O75062_HUMAN relationship: has_participant CCO:B0054602 ! ROCK2_HUMAN relationship: has_participant CCO:B0054605 ! ICOSL_HUMAN relationship: has_participant CCO:B0054609 ! NPHP4_HUMAN relationship: has_participant CCO:B0054613 ! PX11A_HUMAN relationship: has_participant CCO:B0054615 ! RTN2_HUMAN relationship: has_participant CCO:B0054628 ! ULK1_HUMAN relationship: has_participant CCO:B0054630 ! GPR32_HUMAN relationship: has_participant CCO:B0054639 ! NR1I2_HUMAN relationship: has_participant CCO:B0054640 ! LGR5_HUMAN relationship: has_participant CCO:B0054647 ! TNR21_HUMAN relationship: has_participant CCO:B0054650 ! SKAP2_HUMAN relationship: has_participant CCO:B0054661 ! FCN3_HUMAN relationship: has_participant CCO:B0054666 ! RHBL1_HUMAN relationship: has_participant CCO:B0054674 ! TNF13_HUMAN relationship: has_participant CCO:B0054676 ! RASF9_HUMAN relationship: has_participant CCO:B0054680 ! CABYR_HUMAN relationship: has_participant CCO:B0054684 ! OR2B3_HUMAN relationship: has_participant CCO:B0054685 ! OR2J3_HUMAN relationship: has_participant CCO:B0054686 ! OR2J2_HUMAN relationship: has_participant CCO:B0054688 ! NCTR1_HUMAN relationship: has_participant CCO:B0054692 ! PDE5A_HUMAN relationship: has_participant CCO:B0054693 ! PDE9A_HUMAN relationship: has_participant CCO:B0054694 ! OR7C1_HUMAN relationship: has_participant CCO:B0054695 ! OR7AA_HUMAN relationship: has_participant CCO:B0054710 ! LPHN1_HUMAN relationship: has_participant CCO:B0054712 ! NFAT5_HUMAN relationship: has_participant CCO:B0054715 ! OR2F2_HUMAN relationship: has_participant CCO:B0054716 ! O4F21_HUMAN relationship: has_participant CCO:B0054717 ! OR2A4_HUMAN relationship: has_participant CCO:B0054727 ! S1PR2_HUMAN relationship: has_participant CCO:B0054733 ! UNC5C_HUMAN relationship: has_participant CCO:B0054736 ! OR5F1_HUMAN relationship: has_participant CCO:B0054737 ! OR6A2_HUMAN relationship: has_participant CCO:B0054740 ! I18RA_HUMAN relationship: has_participant CCO:B0054741 ! KCNH1_HUMAN relationship: has_participant CCO:B0054742 ! PDE8B_HUMAN relationship: has_participant CCO:B0054743 ! GRP1_HUMAN relationship: has_participant CCO:B0054747 ! RASL1_HUMAN relationship: has_participant CCO:B0054752 ! OR2C1_HUMAN relationship: has_participant CCO:B0054754 ! M3K6_HUMAN relationship: has_participant CCO:B0054755 ! WISP3_HUMAN relationship: has_participant CCO:B0054757 ! RPGF3_HUMAN relationship: has_participant CCO:B0054759 ! CNIH_HUMAN relationship: has_participant CCO:B0054767 ! LPHN2_HUMAN relationship: has_participant CCO:B0054769 ! O95499_HUMAN relationship: has_participant CCO:B0054780 ! NTR2_HUMAN relationship: has_participant CCO:B0054794 ! GPR75_HUMAN relationship: has_participant CCO:B0054798 ! CLIC3_HUMAN relationship: has_participant CCO:B0054799 ! ANGL1_HUMAN relationship: has_participant CCO:B0054800 ! GUC1C_HUMAN relationship: has_participant CCO:B0054804 ! OR2H2_HUMAN relationship: has_participant CCO:B0054807 ! NCTR2_HUMAN relationship: has_participant CCO:B0054813 ! S1PR4_HUMAN relationship: has_participant CCO:B0054818 ! GSUB_HUMAN relationship: has_participant CCO:B0054820 ! PX11B_HUMAN relationship: has_participant CCO:B0054821 ! PAK4_HUMAN relationship: has_participant CCO:B0054822 ! WNT11_HUMAN relationship: has_participant CCO:B0054825 ! LALBA_HUMAN relationship: has_participant CCO:B0054827 ! UROK_HUMAN relationship: has_participant CCO:B0054835 ! GON1_HUMAN relationship: has_participant CCO:B0054836 ! PENK_HUMAN relationship: has_participant CCO:B0054839 ! FSHB_HUMAN relationship: has_participant CCO:B0054840 ! LSHB_HUMAN relationship: has_participant CCO:B0054841 ! CGHB_HUMAN relationship: has_participant CCO:B0054843 ! SOMA_HUMAN relationship: has_participant CCO:B0054844 ! CSH_HUMAN relationship: has_participant CCO:B0054846 ! THYG_HUMAN relationship: has_participant CCO:B0054848 ! GLUC_HUMAN relationship: has_participant CCO:B0054853 ! IGF1A_HUMAN relationship: has_participant CCO:B0054854 ! GAST_HUMAN relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0054858 ! 2B32_HUMAN relationship: has_participant CCO:B0054865 ! FIBA_HUMAN relationship: has_participant CCO:B0054866 ! FIBB_HUMAN relationship: has_participant CCO:B0054867 ! FIBG_HUMAN relationship: has_participant CCO:B0054868 ! ACHA_HUMAN relationship: has_participant CCO:B0054875 ! CXL10_HUMAN relationship: has_participant CCO:B0054879 ! OPSB_HUMAN relationship: has_participant CCO:B0054880 ! OPSR_HUMAN relationship: has_participant CCO:B0054881 ! OPSG_HUMAN relationship: has_participant CCO:B0054883 ! PA21B_HUMAN relationship: has_participant CCO:B0054886 ! GCR_HUMAN relationship: has_participant CCO:B0054888 ! MAS_HUMAN relationship: has_participant CCO:B0054903 ! CCKN_HUMAN relationship: has_participant CCO:B0054904 ! PRGR_HUMAN relationship: has_participant CCO:B0054906 ! CRF_HUMAN relationship: has_participant CCO:B0054912 ! CSF1R_HUMAN relationship: has_participant CCO:B0054913 ! GRP_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054919 ! OPSD_HUMAN relationship: has_participant CCO:B0054921 ! TNR16_HUMAN relationship: has_participant CCO:B0054923 ! ACM2_HUMAN relationship: has_participant CCO:B0054924 ! ACM4_HUMAN relationship: has_participant CCO:B0054925 ! MCR_HUMAN relationship: has_participant CCO:B0054929 ! ADRB1_HUMAN relationship: has_participant CCO:B0054932 ! IBP1_HUMAN relationship: has_participant CCO:B0054934 ! 5HT1A_HUMAN relationship: has_participant CCO:B0054936 ! ACM5_HUMAN relationship: has_participant CCO:B0054937 ! ADA2A_HUMAN relationship: has_participant CCO:B0054938 ! NMB_HUMAN relationship: has_participant CCO:B0054948 ! GIP_HUMAN relationship: has_participant CCO:B0054955 ! OR4A8_HUMAN relationship: has_participant CCO:B0054956 ! O5AL1_HUMAN relationship: has_participant CCO:B0054957 ! OR4Q2_HUMAN relationship: has_participant CCO:B0054958 ! OR5G3_HUMAN relationship: has_participant CCO:B0054959 ! O10J4_HUMAN relationship: has_participant CCO:B0054960 ! OR4E1_HUMAN relationship: has_participant CCO:B0054961 ! O52Z1_HUMAN relationship: has_participant CCO:B0054964 ! OR9G9_HUMAN relationship: has_participant CCO:B0054970 ! CALCB_HUMAN relationship: has_participant CCO:B0054972 ! CCL3_HUMAN relationship: has_participant CCO:B0054974 ! ARRS_HUMAN relationship: has_participant CCO:B0054977 ! KIT_HUMAN relationship: has_participant CCO:B0054984 ! IAPP_HUMAN relationship: has_participant CCO:B0054986 ! ACM1_HUMAN relationship: has_participant CCO:B0054987 ! ACHB_HUMAN relationship: has_participant CCO:B0054988 ! RALA_HUMAN relationship: has_participant CCO:B0054989 ! RALB_HUMAN relationship: has_participant CCO:B0054991 ! ERG_HUMAN relationship: has_participant CCO:B0054992 ! VDR_HUMAN relationship: has_participant CCO:B0054993 ! UTER_HUMAN relationship: has_participant CCO:B0054994 ! MPRI_HUMAN relationship: has_participant CCO:B0054995 ! CD20_HUMAN relationship: has_participant CCO:B0055005 ! SKIL_HUMAN relationship: has_participant CCO:B0055011 ! CCL4_HUMAN relationship: has_participant CCO:B0055013 ! CCL5_HUMAN relationship: has_participant CCO:B0055019 ! 2B14_HUMAN relationship: has_participant CCO:B0055020 ! ADRB3_HUMAN relationship: has_participant CCO:B0055024 ! DRD2_HUMAN relationship: has_participant CCO:B0055033 ! INGR1_HUMAN relationship: has_participant CCO:B0055044 ! CHIN_HUMAN relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055054 ! TSHR_HUMAN relationship: has_participant CCO:B0055055 ! PDE6A_HUMAN relationship: has_participant CCO:B0055056 ! GBB3_HUMAN relationship: has_participant CCO:B0055060 ! IL7RA_HUMAN relationship: has_participant CCO:B0055061 ! PLCG2_HUMAN relationship: has_participant CCO:B0055084 ! TMM11_HUMAN relationship: has_participant CCO:B0055087 ! ASM_HUMAN relationship: has_participant CCO:B0055096 ! PTN1_HUMAN relationship: has_participant CCO:B0055098 ! IBP2_HUMAN relationship: has_participant CCO:B0055104 ! ADA2C_HUMAN relationship: has_participant CCO:B0055106 ! EPOR_HUMAN relationship: has_participant CCO:B0055108 ! CD53_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0055113 ! CD33_HUMAN relationship: has_participant CCO:B0055115 ! ACM3_HUMAN relationship: has_participant CCO:B0055120 ! MCH_HUMAN relationship: has_participant CCO:B0055122 ! TRH_HUMAN relationship: has_participant CCO:B0055123 ! MX1_HUMAN relationship: has_participant CCO:B0055124 ! NTF3_HUMAN relationship: has_participant CCO:B0055128 ! YYY3_HUMAN relationship: has_participant CCO:B0055133 ! CNR1_HUMAN relationship: has_participant CCO:B0055135 ! SCF_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055137 ! C5AR_HUMAN relationship: has_participant CCO:B0055138 ! TA2R_HUMAN relationship: has_participant CCO:B0055139 ! DRD4_HUMAN relationship: has_participant CCO:B0055140 ! DRD5_HUMAN relationship: has_participant CCO:B0055141 ! TENX_HUMAN relationship: has_participant CCO:B0055144 ! CCL1_HUMAN relationship: has_participant CCO:B0055149 ! IBP4_HUMAN relationship: has_participant CCO:B0055150 ! NR4A1_HUMAN relationship: has_participant CCO:B0055152 ! LSHR_HUMAN relationship: has_participant CCO:B0055160 ! TNFL4_HUMAN relationship: has_participant CCO:B0055161 ! IP3KA_HUMAN relationship: has_participant CCO:B0055170 ! CRHBP_HUMAN relationship: has_participant CCO:B0055171 ! IL4RA_HUMAN relationship: has_participant CCO:B0055172 ! AKAP5_HUMAN relationship: has_participant CCO:B0055173 ! IBP6_HUMAN relationship: has_participant CCO:B0055174 ! IBP5_HUMAN relationship: has_participant CCO:B0055175 ! CXCR1_HUMAN relationship: has_participant CCO:B0055176 ! CXCR2_HUMAN relationship: has_participant CCO:B0055178 ! FPR3_HUMAN relationship: has_participant CCO:B0055179 ! FPR2_HUMAN relationship: has_participant CCO:B0055180 ! ARBK1_HUMAN relationship: has_participant CCO:B0055181 ! PTAFR_HUMAN relationship: has_participant CCO:B0055182 ! CXCR7_HUMAN relationship: has_participant CCO:B0055187 ! NPY1R_HUMAN relationship: has_participant CCO:B0055188 ! TNR5_HUMAN relationship: has_participant CCO:B0055191 ! AMFR1_HUMAN relationship: has_participant CCO:B0055192 ! NKG2D_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN relationship: has_participant CCO:B0055195 ! PDE4A_HUMAN relationship: has_participant CCO:B0055197 ! 5HT1B_HUMAN relationship: has_participant CCO:B0055198 ! 5HT2A_HUMAN relationship: has_participant CCO:B0055201 ! NMBR_HUMAN relationship: has_participant CCO:B0055205 ! 5HT1E_HUMAN relationship: has_participant CCO:B0055207 ! CD38_HUMAN relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN relationship: has_participant CCO:B0055211 ! AA2BR_HUMAN relationship: has_participant CCO:B0055212 ! RABP2_HUMAN relationship: has_participant CCO:B0055214 ! LTK_HUMAN relationship: has_participant CCO:B0055215 ! NOS3_HUMAN relationship: has_participant CCO:B0055218 ! BKRB2_HUMAN relationship: has_participant CCO:B0055219 ! V2R_HUMAN relationship: has_participant CCO:B0055221 ! AA1R_HUMAN relationship: has_participant CCO:B0055222 ! GRPR_HUMAN relationship: has_participant CCO:B0055223 ! AGTR1_HUMAN relationship: has_participant CCO:B0055224 ! OXYR_HUMAN relationship: has_participant CCO:B0055225 ! GNA15_HUMAN relationship: has_participant CCO:B0055226 ! 5HT1F_HUMAN relationship: has_participant CCO:B0055227 ! OR1E1_HUMAN relationship: has_participant CCO:B0055228 ! O10J1_HUMAN relationship: has_participant CCO:B0055229 ! GNRHR_HUMAN relationship: has_participant CCO:B0055230 ! CALCR_HUMAN relationship: has_participant CCO:B0055231 ! NTR1_HUMAN relationship: has_participant CCO:B0055232 ! NEUT_HUMAN relationship: has_participant CCO:B0055233 ! GDIA_HUMAN relationship: has_participant CCO:B0055246 ! IL2RG_HUMAN relationship: has_participant CCO:B0055247 ! FCG2B_HUMAN relationship: has_participant CCO:B0055248 ! I5P2_HUMAN relationship: has_participant CCO:B0055250 ! ARRB2_HUMAN relationship: has_participant CCO:B0055251 ! CCKAR_HUMAN relationship: has_participant CCO:B0055252 ! GASR_HUMAN relationship: has_participant CCO:B0055253 ! VIPR1_HUMAN relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055257 ! BRS3_HUMAN relationship: has_participant CCO:B0055258 ! CCR7_HUMAN relationship: has_participant CCO:B0055259 ! GRK4_HUMAN relationship: has_participant CCO:B0055260 ! CXCR5_HUMAN relationship: has_participant CCO:B0055261 ! STX2_HUMAN relationship: has_participant CCO:B0055262 ! CD70_HUMAN relationship: has_participant CCO:B0055263 ! TNFL8_HUMAN relationship: has_participant CCO:B0055265 ! LSP1_HUMAN relationship: has_participant CCO:B0055267 ! GCYA2_HUMAN relationship: has_participant CCO:B0055269 ! AA3R_HUMAN relationship: has_participant CCO:B0055271 ! GRK5_HUMAN relationship: has_participant CCO:B0055272 ! 5HT7R_HUMAN relationship: has_participant CCO:B0055273 ! CNR2_HUMAN relationship: has_participant CCO:B0055274 ! TRFR_HUMAN relationship: has_participant CCO:B0055275 ! PE2R1_HUMAN relationship: has_participant CCO:B0055276 ! CRFR1_HUMAN relationship: has_participant CCO:B0055281 ! RECO_HUMAN relationship: has_participant CCO:B0055286 ! ADML_HUMAN relationship: has_participant CCO:B0055287 ! HRH1_HUMAN relationship: has_participant CCO:B0055288 ! PE2R4_HUMAN relationship: has_participant CCO:B0055289 ! MAS1L_HUMAN relationship: has_participant CCO:B0055290 ! APJ_HUMAN relationship: has_participant CCO:B0055293 ! DRD3_HUMAN relationship: has_participant CCO:B0055295 ! TIE1_HUMAN relationship: has_participant CCO:B0055298 ! ARBK2_HUMAN relationship: has_participant CCO:B0055303 ! PDE6B_HUMAN relationship: has_participant CCO:B0055310 ! ACHA7_HUMAN relationship: has_participant CCO:B0055311 ! ARRC_HUMAN relationship: has_participant CCO:B0055312 ! GNL1_HUMAN relationship: has_participant CCO:B0055313 ! TNR3_HUMAN relationship: has_participant CCO:B0055318 ! V1AR_HUMAN relationship: has_participant CCO:B0055323 ! GDNF_HUMAN relationship: has_participant CCO:B0055325 ! ADCY8_HUMAN relationship: has_participant CCO:B0055328 ! CD79B_HUMAN relationship: has_participant CCO:B0055332 ! IL15_HUMAN relationship: has_participant CCO:B0055333 ! LEP_HUMAN relationship: has_participant CCO:B0055335 ! CASR_HUMAN relationship: has_participant CCO:B0055336 ! WNT5A_HUMAN relationship: has_participant CCO:B0055338 ! P2RY2_HUMAN relationship: has_participant CCO:B0055340 ! TNFL9_HUMAN relationship: has_participant CCO:B0055341 ! PACR_HUMAN relationship: has_participant CCO:B0055342 ! VIPR2_HUMAN relationship: has_participant CCO:B0055343 ! 5HT2B_HUMAN relationship: has_participant CCO:B0055344 ! CCR2_HUMAN relationship: has_participant CCO:B0055345 ! ELK3_HUMAN relationship: has_participant CCO:B0055347 ! ASIP_HUMAN relationship: has_participant CCO:B0055349 ! RHG25_HUMAN relationship: has_participant CCO:B0055350 ! PI4KA_HUMAN relationship: has_participant CCO:B0055354 ! I12R1_HUMAN relationship: has_participant CCO:B0055357 ! GUC1A_HUMAN relationship: has_participant CCO:B0055358 ! PF2R_HUMAN relationship: has_participant CCO:B0055359 ! PE2R2_HUMAN relationship: has_participant CCO:B0055360 ! PI2R_HUMAN relationship: has_participant CCO:B0055361 ! GRK6_HUMAN relationship: has_participant CCO:B0055363 ! NR4A2_HUMAN relationship: has_participant CCO:B0055364 ! ZAP70_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0055366 ! NAMPT_HUMAN relationship: has_participant CCO:B0055367 ! P2RY5_HUMAN relationship: has_participant CCO:B0055368 ! ACHA4_HUMAN relationship: has_participant CCO:B0055372 ! GPR3_HUMAN relationship: has_participant CCO:B0055373 ! GPR1_HUMAN relationship: has_participant CCO:B0055374 ! XCR1_HUMAN relationship: has_participant CCO:B0055375 ! GPR6_HUMAN relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0055378 ! BKRB1_HUMAN relationship: has_participant CCO:B0055382 ! GALR1_HUMAN relationship: has_participant CCO:B0055384 ! RPGP1_HUMAN relationship: has_participant CCO:B0055385 ! GPR12_HUMAN relationship: has_participant CCO:B0055386 ! RGR_HUMAN relationship: has_participant CCO:B0055387 ! OMP_HUMAN relationship: has_participant CCO:B0055388 ! OR3A1_HUMAN relationship: has_participant CCO:B0055389 ! OR3A4_HUMAN relationship: has_participant CCO:B0055390 ! OR1G1_HUMAN relationship: has_participant CCO:B0055391 ! OR3A2_HUMAN relationship: has_participant CCO:B0055393 ! 5HT5A_HUMAN relationship: has_participant CCO:B0055394 ! P2RY1_HUMAN relationship: has_participant CCO:B0055395 ! V1BR_HUMAN relationship: has_participant CCO:B0055397 ! XCL1_HUMAN relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0055399 ! SDF1_HUMAN relationship: has_participant CCO:B0055409 ! NMU_HUMAN relationship: has_participant CCO:B0055410 ! KC1A_HUMAN relationship: has_participant CCO:B0055413 ! CD97_HUMAN relationship: has_participant CCO:B0055414 ! G109B_HUMAN relationship: has_participant CCO:B0055415 ! CAMLG_HUMAN relationship: has_participant CCO:B0055418 ! NPY2R_HUMAN relationship: has_participant CCO:B0055419 ! PTH2R_HUMAN relationship: has_participant CCO:B0055420 ! CX3C1_HUMAN relationship: has_participant CCO:B0055424 ! ARRB1_HUMAN relationship: has_participant CCO:B0055425 ! DGKG_HUMAN relationship: has_participant CCO:B0055428 ! CXCR3_HUMAN relationship: has_participant CCO:B0055429 ! PRLHR_HUMAN relationship: has_participant CCO:B0055430 ! GPR15_HUMAN relationship: has_participant CCO:B0055435 ! FLT3L_HUMAN relationship: has_participant CCO:B0055436 ! HINT1_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055443 ! GBG4_HUMAN relationship: has_participant CCO:B0055444 ! GBG10_HUMAN relationship: has_participant CCO:B0055447 ! NPY4R_HUMAN relationship: has_participant CCO:B0055448 ! GDIB_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055456 ! LU_HUMAN relationship: has_participant CCO:B0055460 ! PDE6C_HUMAN relationship: has_participant CCO:B0055462 ! PLCD1_HUMAN relationship: has_participant CCO:B0055468 ! P2RX1_HUMAN relationship: has_participant CCO:B0055469 ! P2RY4_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0055472 ! CCR3_HUMAN relationship: has_participant CCO:B0055473 ! CCR4_HUMAN relationship: has_participant CCO:B0055474 ! CCR5_HUMAN relationship: has_participant CCO:B0055475 ! CCR6_HUMAN relationship: has_participant CCO:B0055476 ! CCR8_HUMAN relationship: has_participant CCO:B0055477 ! CCR9_HUMAN relationship: has_participant CCO:B0055479 ! CLCN6_HUMAN relationship: has_participant CCO:B0055480 ! PLXA3_HUMAN relationship: has_participant CCO:B0055484 ! HDGF_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN relationship: has_participant CCO:B0055500 ! CHIO_HUMAN relationship: has_participant CCO:B0055503 ! DGKQ_HUMAN relationship: has_participant CCO:B0055512 ! RCAN1_HUMAN relationship: has_participant CCO:B0055514 ! AAPK2_HUMAN relationship: has_participant CCO:B0055515 ! PDE1A_HUMAN relationship: has_participant CCO:B0055516 ! DVL1L_HUMAN relationship: has_participant CCO:B0055522 ! DRG2_HUMAN relationship: has_participant CCO:B0055523 ! GEM_HUMAN relationship: has_participant CCO:B0055537 ! CCL23_HUMAN relationship: has_participant CCO:B0055540 ! TPTE_HUMAN relationship: has_participant CCO:B0055544 ! P2RX3_HUMAN relationship: has_participant CCO:B0055555 ! HUNK_HUMAN relationship: has_participant CCO:B0055563 ! KCNKA_HUMAN relationship: has_participant CCO:B0055564 ! CABP4_HUMAN relationship: has_participant CCO:B0055565 ! OR2B6_HUMAN relationship: has_participant CCO:B0055566 ! OR4D2_HUMAN relationship: has_participant CCO:B0055567 ! O10A3_HUMAN relationship: has_participant CCO:B0055568 ! O12D2_HUMAN relationship: has_participant CCO:B0055572 ! TIRAP_HUMAN relationship: has_participant CCO:B0055573 ! RHBL3_HUMAN relationship: has_participant CCO:B0055574 ! NAL12_HUMAN relationship: has_participant CCO:B0055576 ! T2R12_HUMAN relationship: has_participant CCO:B0055577 ! T2R38_HUMAN relationship: has_participant CCO:B0055578 ! T2R39_HUMAN relationship: has_participant CCO:B0055579 ! T2R41_HUMAN relationship: has_participant CCO:B0055580 ! T2R43_HUMAN relationship: has_participant CCO:B0055581 ! T2R44_HUMAN relationship: has_participant CCO:B0055582 ! T2R45_HUMAN relationship: has_participant CCO:B0055583 ! T2R46_HUMAN relationship: has_participant CCO:B0055584 ! T2R47_HUMAN relationship: has_participant CCO:B0055585 ! T2R48_HUMAN relationship: has_participant CCO:B0055586 ! T2R49_HUMAN relationship: has_participant CCO:B0055587 ! T2R50_HUMAN relationship: has_participant CCO:B0055588 ! T2R60_HUMAN relationship: has_participant CCO:B0055589 ! GBG2_HUMAN relationship: has_participant CCO:B0055592 ! OR2B8_HUMAN relationship: has_participant CCO:B0055599 ! GPR85_HUMAN relationship: has_participant CCO:B0055600 ! S10AA_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN relationship: has_participant CCO:B0055605 ! CSN2_HUMAN relationship: has_participant CCO:B0055614 ! GBG11_HUMAN relationship: has_participant CCO:B0055621 ! GBB1_HUMAN relationship: has_participant CCO:B0055623 ! GBB2_HUMAN relationship: has_participant CCO:B0055631 ! GBG1_HUMAN relationship: has_participant CCO:B0055632 ! GBG3_HUMAN relationship: has_participant CCO:B0055633 ! GBG5_HUMAN relationship: has_participant CCO:B0055636 ! 3BP2_HUMAN relationship: has_participant CCO:B0055637 ! IGBP1_HUMAN relationship: has_participant CCO:B0055639 ! ACCN2_HUMAN relationship: has_participant CCO:B0055641 ! CNTP1_HUMAN relationship: has_participant CCO:B0055651 ! P78548_HUMAN relationship: has_participant CCO:B0055653 ! CCL20_HUMAN relationship: has_participant CCO:B0055654 ! SIM1_HUMAN relationship: has_participant CCO:B0055664 ! RHG08_HUMAN relationship: has_participant CCO:B0055666 ! TSG6_HUMAN relationship: has_participant CCO:B0055669 ! VLDLR_HUMAN relationship: has_participant CCO:B0055675 ! RHG04_HUMAN relationship: has_participant CCO:B0055676 ! FGD1_HUMAN relationship: has_participant CCO:B0055681 ! NDP_HUMAN relationship: has_participant CCO:B0055683 ! PDE1B_HUMAN relationship: has_participant CCO:B0055686 ! IL9R_HUMAN relationship: has_participant CCO:B0055687 ! CD83_HUMAN relationship: has_participant CCO:B0055688 ! IL5RA_HUMAN relationship: has_participant CCO:B0055691 ! ILRL1_HUMAN relationship: has_participant CCO:B0055698 ! OCRL_HUMAN relationship: has_participant CCO:B0055700 ! ROR2_HUMAN relationship: has_participant CCO:B0055701 ! SF17A_HUMAN relationship: has_participant CCO:B0055707 ! TNR17_HUMAN relationship: has_participant CCO:B0055713 ! GHRHR_HUMAN relationship: has_participant CCO:B0055714 ! GUC2A_HUMAN relationship: has_participant CCO:B0055715 ! TIE2_HUMAN relationship: has_participant CCO:B0055716 ! RASF7_HUMAN relationship: has_participant CCO:B0055718 ! AKA12_HUMAN relationship: has_participant CCO:B0055719 ! CREM_HUMAN relationship: has_participant CCO:B0055721 ! GNA12_HUMAN relationship: has_participant CCO:B0055723 ! UPAR_HUMAN relationship: has_participant CCO:B0055724 ! PTHR1_HUMAN relationship: has_participant CCO:B0055738 ! MUC24_HUMAN relationship: has_participant CCO:B0055739 ! RON_HUMAN relationship: has_participant CCO:B0055745 ! KPCD_HUMAN relationship: has_participant CCO:B0055747 ! Q05AH0_HUMAN relationship: has_participant CCO:B0055748 ! Q05B42_HUMAN relationship: has_participant CCO:B0055749 ! Q05BE4_HUMAN relationship: has_participant CCO:B0055765 ! PTN11_HUMAN relationship: has_participant CCO:B0055770 ! TNFC_HUMAN relationship: has_participant CCO:B0055777 ! Q06976_HUMAN relationship: has_participant CCO:B0055779 ! ACHD_HUMAN relationship: has_participant CCO:B0055783 ! CXCL9_HUMAN relationship: has_participant CCO:B0055784 ! PDE4B_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN relationship: has_participant CCO:B0055789 ! LG3BP_HUMAN relationship: has_participant CCO:B0055790 ! PDE4C_HUMAN relationship: has_participant CCO:B0055792 ! PDE4D_HUMAN relationship: has_participant CCO:B0055795 ! FGL1_HUMAN relationship: has_participant CCO:B0055796 ! ITK_HUMAN relationship: has_participant CCO:B0055797 ! Q08AC8_HUMAN relationship: has_participant CCO:B0055799 ! VAC14_HUMAN relationship: has_participant CCO:B0055800 ! Q08AQ7_HUMAN relationship: has_participant CCO:B0055807 ! Q09LL4_HUMAN relationship: has_participant CCO:B0055810 ! Q0EFC9_HUMAN relationship: has_participant CCO:B0055818 ! PLCX2_HUMAN relationship: has_participant CCO:B0055826 ! Q0VFZ9_HUMAN relationship: has_participant CCO:B0055844 ! KCNH2_HUMAN relationship: has_participant CCO:B0055849 ! Q12843_HUMAN relationship: has_participant CCO:B0055861 ! ABR_HUMAN relationship: has_participant CCO:B0055865 ! TIAM1_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0055885 ! STK3_HUMAN relationship: has_participant CCO:B0055890 ! PD2R_HUMAN relationship: has_participant CCO:B0055891 ! I15RA_HUMAN relationship: has_participant CCO:B0055892 ! STF1_HUMAN relationship: has_participant CCO:B0055895 ! GPR17_HUMAN relationship: has_participant CCO:B0055896 ! PTK7_HUMAN relationship: has_participant CCO:B0055897 ! GRB10_HUMAN relationship: has_participant CCO:B0055898 ! CRFR2_HUMAN relationship: has_participant CCO:B0055899 ! MTA1_HUMAN relationship: has_participant CCO:B0055902 ! PDE3B_HUMAN relationship: has_participant CCO:B0055903 ! PHLP_HUMAN relationship: has_participant CCO:B0055908 ! HAP28_HUMAN relationship: has_participant CCO:B0055909 ! TMED1_HUMAN relationship: has_participant CCO:B0055910 ! ROCK1_HUMAN relationship: has_participant CCO:B0055912 ! MADCA_HUMAN relationship: has_participant CCO:B0055913 ! IL18R_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN relationship: has_participant CCO:B0055923 ! PNOC_HUMAN relationship: has_participant CCO:B0055924 ! PPR1A_HUMAN relationship: has_participant CCO:B0055931 ! ITPK1_HUMAN relationship: has_participant CCO:B0055932 ! DGKZ_HUMAN relationship: has_participant CCO:B0055934 ! OR2F1_HUMAN relationship: has_participant CCO:B0055937 ! 5HT4R_HUMAN relationship: has_participant CCO:B0055940 ! AVR2B_HUMAN relationship: has_participant CCO:B0055942 ! ARFRP_HUMAN relationship: has_participant CCO:B0055947 ! PKP1_HUMAN relationship: has_participant CCO:B0055948 ! Q13850_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: has_participant CCO:B0055959 ! PDE1C_HUMAN relationship: has_participant CCO:B0055966 ! ARHG7_HUMAN relationship: has_participant CCO:B0055968 ! MPP2_HUMAN relationship: has_participant CCO:B0055969 ! SIM2_HUMAN relationship: has_participant CCO:B0055970 ! DPYL3_HUMAN relationship: has_participant CCO:B0055973 ! EPAG_HUMAN relationship: has_participant CCO:B0055975 ! EMR1_HUMAN relationship: has_participant CCO:B0055976 ! FASTK_HUMAN relationship: has_participant CCO:B0055977 ! FGL2_HUMAN relationship: has_participant CCO:B0055979 ! GPR18_HUMAN relationship: has_participant CCO:B0055982 ! PDE3A_HUMAN relationship: has_participant CCO:B0055983 ! GP176_HUMAN relationship: has_participant CCO:B0055984 ! GRB14_HUMAN relationship: has_participant CCO:B0055985 ! GRB7_HUMAN relationship: has_participant CCO:B0055994 ! ITPR2_HUMAN relationship: has_participant CCO:B0055995 ! ITPR3_HUMAN relationship: has_participant CCO:B0056006 ! INSL4_HUMAN relationship: has_participant CCO:B0056007 ! ITPR1_HUMAN relationship: has_participant CCO:B0056008 ! RASA3_HUMAN relationship: has_participant CCO:B0056030 ! NR1I3_HUMAN relationship: has_participant CCO:B0056032 ! GAPD1_HUMAN relationship: has_participant CCO:B0056033 ! RHG19_HUMAN relationship: has_participant CCO:B0056037 ! SNX17_HUMAN relationship: has_participant CCO:B0056042 ! P2RY6_HUMAN relationship: has_participant CCO:B0056044 ! PLCL1_HUMAN relationship: has_participant CCO:B0056047 ! PLCB4_HUMAN relationship: has_participant CCO:B0056049 ! TEBP_HUMAN relationship: has_participant CCO:B0056050 ! PWP2_HUMAN relationship: has_participant CCO:B0056052 ! RASA2_HUMAN relationship: has_participant CCO:B0056057 ! RBP1_HUMAN relationship: has_participant CCO:B0056058 ! ANKR1_HUMAN relationship: has_participant CCO:B0056059 ! ANGP1_HUMAN relationship: has_participant CCO:B0056060 ! P2Y14_HUMAN relationship: has_participant CCO:B0056061 ! RSU1_HUMAN relationship: has_participant CCO:B0056065 ! SHB_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056071 ! SP17_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0056078 ! OR1Q1_HUMAN relationship: has_participant CCO:B0056079 ! OR4D1_HUMAN relationship: has_participant CCO:B0056080 ! OR1C1_HUMAN relationship: has_participant CCO:B0056081 ! OR8B8_HUMAN relationship: has_participant CCO:B0056082 ! OR7A5_HUMAN relationship: has_participant CCO:B0056090 ! CIP4_HUMAN relationship: has_participant CCO:B0056100 ! LT4R1_HUMAN relationship: has_participant CCO:B0056104 ! GPR19_HUMAN relationship: has_participant CCO:B0056105 ! NPY5R_HUMAN relationship: has_participant CCO:B0056106 ! CD226_HUMAN relationship: has_participant CCO:B0056112 ! NCOA1_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056114 ! SMAD1_HUMAN relationship: has_participant CCO:B0056115 ! RK_HUMAN relationship: has_participant CCO:B0056124 ! Q16002_HUMAN relationship: has_participant CCO:B0056125 ! Q16003_HUMAN relationship: has_participant CCO:B0056132 ! CNGA3_HUMAN relationship: has_participant CCO:B0056134 ! Q16293_HUMAN relationship: has_participant CCO:B0056146 ! GP162_HUMAN relationship: has_participant CCO:B0056150 ! DPYL2_HUMAN relationship: has_participant CCO:B0056152 ! CART_HUMAN relationship: has_participant CCO:B0056153 ! DUFFY_HUMAN relationship: has_participant CCO:B0056154 ! C3AR_HUMAN relationship: has_participant CCO:B0056166 ! MAPK3_HUMAN relationship: has_participant CCO:B0056171 ! CCL15_HUMAN relationship: has_participant CCO:B0056176 ! DGKD_HUMAN relationship: has_participant CCO:B0056177 ! RTN1_HUMAN relationship: has_participant CCO:B0056178 ! DDR2_HUMAN relationship: has_participant CCO:B0056179 ! TRXR1_HUMAN relationship: has_participant CCO:B0056181 ! Q17R53_HUMAN relationship: has_participant CCO:B0056186 ! Q17RR2_HUMAN relationship: has_participant CCO:B0056189 ! Q17S10_HUMAN relationship: has_participant CCO:B0056196 ! Q1WD23_HUMAN relationship: has_participant CCO:B0056207 ! CDGAP_HUMAN relationship: has_participant CCO:B0056211 ! Q2M3M4_HUMAN relationship: has_participant CCO:B0056212 ! Q2M3U3_HUMAN relationship: has_participant CCO:B0056219 ! Q2NL85_HUMAN relationship: has_participant CCO:B0056231 ! Q2TBE4_HUMAN relationship: has_participant CCO:B0056241 ! OR4FL_HUMAN relationship: has_participant CCO:B0056247 ! Q3C1V0_HUMAN relationship: has_participant CCO:B0056259 ! Q3KRA7_HUMAN relationship: has_participant CCO:B0056260 ! RHGBB_HUMAN relationship: has_participant CCO:B0056284 ! Q3ZCR0_HUMAN relationship: has_participant CCO:B0056293 ! AKD1A_HUMAN relationship: has_participant CCO:B0056294 ! Q495I2_HUMAN relationship: has_participant CCO:B0056295 ! Q495P6_HUMAN relationship: has_participant CCO:B0056306 ! Q49AP2_HUMAN relationship: has_participant CCO:B0056308 ! GPR33_HUMAN relationship: has_participant CCO:B0056316 ! Q4JF27_HUMAN relationship: has_participant CCO:B0056320 ! PLCH1_HUMAN relationship: has_participant CCO:B0056330 ! Q4VBL7_HUMAN relationship: has_participant CCO:B0056333 ! Q4VY10_HUMAN relationship: has_participant CCO:B0056336 ! Q4W5L4_HUMAN relationship: has_participant CCO:B0056342 ! Q50KZ9_HUMAN relationship: has_participant CCO:B0056343 ! RHG29_HUMAN relationship: has_participant CCO:B0056345 ! Q52R92_HUMAN relationship: has_participant CCO:B0056346 ! Q52R94_HUMAN relationship: has_participant CCO:B0056353 ! Q53F22_HUMAN relationship: has_participant CCO:B0056355 ! Q53F99_HUMAN relationship: has_participant CCO:B0056370 ! Q54AJ0_HUMAN relationship: has_participant CCO:B0056378 ! Q59ED4_HUMAN relationship: has_participant CCO:B0056381 ! Q59EM3_HUMAN relationship: has_participant CCO:B0056388 ! Q59F62_HUMAN relationship: has_participant CCO:B0056392 ! Q59FL5_HUMAN relationship: has_participant CCO:B0056396 ! Q59G20_HUMAN relationship: has_participant CCO:B0056408 ! Q59GK8_HUMAN relationship: has_participant CCO:B0056417 ! Q59HG6_HUMAN relationship: has_participant CCO:B0056429 ! Q5GJ68_HUMAN relationship: has_participant CCO:B0056437 ! Q5H9B2_HUMAN relationship: has_participant CCO:B0056443 ! Q5HYD7_HUMAN relationship: has_participant CCO:B0056449 ! M4A13_HUMAN relationship: has_participant CCO:B0056456 ! AKAP4_HUMAN relationship: has_participant CCO:B0056459 ! OR2BB_HUMAN relationship: has_participant CCO:B0056469 ! Q5JRM1_HUMAN relationship: has_participant CCO:B0056470 ! O10J3_HUMAN relationship: has_participant CCO:B0056477 ! Q5JSD4_HUMAN relationship: has_participant CCO:B0056478 ! Q5JSD8_HUMAN relationship: has_participant CCO:B0056479 ! Q5JSM8_HUMAN relationship: has_participant CCO:B0056511 ! Q5JYT3_HUMAN relationship: has_participant CCO:B0056519 ! Q5KU21_HUMAN relationship: has_participant CCO:B0056524 ! GP120_HUMAN relationship: has_participant CCO:B0056525 ! Q5QD39_HUMAN relationship: has_participant CCO:B0056536 ! Q5SSB9_HUMAN relationship: has_participant CCO:B0056537 ! Q5ST39_HUMAN relationship: has_participant CCO:B0056539 ! Q5SUJ6_HUMAN relationship: has_participant CCO:B0056540 ! Q5SUJ7_HUMAN relationship: has_participant CCO:B0056541 ! Q5SUK1_HUMAN relationship: has_participant CCO:B0056542 ! Q5SUN7_HUMAN relationship: has_participant CCO:B0056543 ! Q5SUN9_HUMAN relationship: has_participant CCO:B0056563 ! Q5T1N8_HUMAN relationship: has_participant CCO:B0056570 ! Q5T3S6_HUMAN relationship: has_participant CCO:B0056571 ! Q5T3S7_HUMAN relationship: has_participant CCO:B0056572 ! Q5T3S9_HUMAN relationship: has_participant CCO:B0056573 ! Q5T3T0_HUMAN relationship: has_participant CCO:B0056574 ! Q5T3T1_HUMAN relationship: has_participant CCO:B0056575 ! SFRP5_HUMAN relationship: has_participant CCO:B0056578 ! ARTN_HUMAN relationship: has_participant CCO:B0056584 ! RHG21_HUMAN relationship: has_participant CCO:B0056585 ! Q5T5Y4_HUMAN relationship: has_participant CCO:B0056586 ! GP110_HUMAN relationship: has_participant CCO:B0056592 ! GPC6A_HUMAN relationship: has_participant CCO:B0056596 ! GP158_HUMAN relationship: has_participant CCO:B0056604 ! DEP1A_HUMAN relationship: has_participant CCO:B0056614 ! Q5TEK5_HUMAN relationship: has_participant CCO:B0056619 ! RG18L_HUMAN relationship: has_participant CCO:B0056629 ! Q5TIG5_HUMAN relationship: has_participant CCO:B0056630 ! Q5TIG7_HUMAN relationship: has_participant CCO:B0056631 ! Q5TIH0_HUMAN relationship: has_participant CCO:B0056632 ! Q5TIH1_HUMAN relationship: has_participant CCO:B0056637 ! OR2G6_HUMAN relationship: has_participant CCO:B0056639 ! RAIN_HUMAN relationship: has_participant CCO:B0056640 ! GP157_HUMAN relationship: has_participant CCO:B0056643 ! GKAP1_HUMAN relationship: has_participant CCO:B0056645 ! Q5VT14_HUMAN relationship: has_participant CCO:B0056649 ! SYDE2_HUMAN relationship: has_participant CCO:B0056664 ! Q5VWL4_HUMAN relationship: has_participant CCO:B0056665 ! Q5VX04_HUMAN relationship: has_participant CCO:B0056673 ! Q5VZB4_HUMAN relationship: has_participant CCO:B0056676 ! RRAGB_HUMAN relationship: has_participant CCO:B0056684 ! Q5YLW1_HUMAN relationship: has_participant CCO:B0056688 ! PLCX3_HUMAN relationship: has_participant CCO:B0056691 ! Q63ZY2_HUMAN relationship: has_participant CCO:B0056704 ! Q68DL5_HUMAN relationship: has_participant CCO:B0056706 ! Q68DZ5_HUMAN relationship: has_participant CCO:B0056730 ! GP139_HUMAN relationship: has_participant CCO:B0056733 ! SFRP4_HUMAN relationship: has_participant CCO:B0056752 ! Q6I939_HUMAN relationship: has_participant CCO:B0056753 ! Q6I940_HUMAN relationship: has_participant CCO:B0056754 ! Q6I941_HUMAN relationship: has_participant CCO:B0056756 ! SIGIR_HUMAN relationship: has_participant CCO:B0056758 ! Q6IB99_HUMAN relationship: has_participant CCO:B0056760 ! OR5MA_HUMAN relationship: has_participant CCO:B0056762 ! Q6IEV1_HUMAN relationship: has_participant CCO:B0056763 ! Q6IEV3_HUMAN relationship: has_participant CCO:B0056764 ! OR4CB_HUMAN relationship: has_participant CCO:B0056765 ! Q6IEW7_HUMAN relationship: has_participant CCO:B0056766 ! Q6IEX0_HUMAN relationship: has_participant CCO:B0056767 ! Q6IEX5_HUMAN relationship: has_participant CCO:B0056768 ! OR4F3_HUMAN relationship: has_participant CCO:B0056769 ! Q6IEZ1_HUMAN relationship: has_participant CCO:B0056770 ! Q6IEZ4_HUMAN relationship: has_participant CCO:B0056771 ! OR2T5_HUMAN relationship: has_participant CCO:B0056772 ! OR2T2_HUMAN relationship: has_participant CCO:B0056773 ! Q6IF09_HUMAN relationship: has_participant CCO:B0056774 ! Q6IF12_HUMAN relationship: has_participant CCO:B0056775 ! Q6IF17_HUMAN relationship: has_participant CCO:B0056776 ! Q6IF36_HUMAN relationship: has_participant CCO:B0056777 ! Q6IF40_HUMAN relationship: has_participant CCO:B0056778 ! OR2A2_HUMAN relationship: has_participant CCO:B0056779 ! Q6IF52_HUMAN relationship: has_participant CCO:B0056780 ! O52W1_HUMAN relationship: has_participant CCO:B0056781 ! Q6IF70_HUMAN relationship: has_participant CCO:B0056782 ! Q6IF79_HUMAN relationship: has_participant CCO:B0056783 ! O4A47_HUMAN relationship: has_participant CCO:B0056784 ! O10K2_HUMAN relationship: has_participant CCO:B0056785 ! Q6IFB0_HUMAN relationship: has_participant CCO:B0056786 ! Q6IFD1_HUMAN relationship: has_participant CCO:B0056787 ! Q6IFD3_HUMAN relationship: has_participant CCO:B0056788 ! Q6IFD6_HUMAN relationship: has_participant CCO:B0056789 ! O52E8_HUMAN relationship: has_participant CCO:B0056790 ! Q6IFG3_HUMAN relationship: has_participant CCO:B0056791 ! Q6IFG5_HUMAN relationship: has_participant CCO:B0056792 ! Q6IFG6_HUMAN relationship: has_participant CCO:B0056793 ! Q6IFG8_HUMAN relationship: has_participant CCO:B0056794 ! OR6B2_HUMAN relationship: has_participant CCO:B0056795 ! Q6IFH9_HUMAN relationship: has_participant CCO:B0056796 ! Q6IFI0_HUMAN relationship: has_participant CCO:B0056797 ! Q6IFI1_HUMAN relationship: has_participant CCO:B0056798 ! Q6IFI5_HUMAN relationship: has_participant CCO:B0056799 ! Q6IFI7_HUMAN relationship: has_participant CCO:B0056800 ! Q6IFI8_HUMAN relationship: has_participant CCO:B0056801 ! Q6IFJ4_HUMAN relationship: has_participant CCO:B0056802 ! Q6IFJ8_HUMAN relationship: has_participant CCO:B0056803 ! Q6IFK7_HUMAN relationship: has_participant CCO:B0056804 ! Q6IFK8_HUMAN relationship: has_participant CCO:B0056805 ! Q6IFK9_HUMAN relationship: has_participant CCO:B0056806 ! 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CSPG4_HUMAN relationship: has_participant CCO:B0056954 ! Q6UXT6_HUMAN relationship: has_participant CCO:B0056956 ! BI2L2_HUMAN relationship: has_participant CCO:B0056957 ! UNC5D_HUMAN relationship: has_participant CCO:B0056968 ! NPSR1_HUMAN relationship: has_participant CCO:B0056989 ! Q6ZMP9_HUMAN relationship: has_participant CCO:B0056990 ! Q6ZMR1_HUMAN relationship: has_participant CCO:B0056994 ! YD026_HUMAN relationship: has_participant CCO:B0057004 ! Q6ZN13_HUMAN relationship: has_participant CCO:B0057010 ! UNC5A_HUMAN relationship: has_participant CCO:B0057034 ! Q6ZQV4_HUMAN relationship: has_participant CCO:B0057040 ! RHGXX_HUMAN relationship: has_participant CCO:B0057055 ! Q6ZSK3_HUMAN relationship: has_participant CCO:B0057065 ! Q6ZT60_HUMAN relationship: has_participant CCO:B0057066 ! Q6ZT62_HUMAN relationship: has_participant CCO:B0057070 ! Q6ZTJ5_HUMAN relationship: has_participant CCO:B0057072 ! Q6ZTY0_HUMAN relationship: has_participant CCO:B0057073 ! Q6ZTY7_HUMAN relationship: has_participant CCO:B0057082 ! BCRL1_HUMAN relationship: has_participant CCO:B0057085 ! Q6ZVN1_HUMAN relationship: has_participant CCO:B0057086 ! Q6ZVX3_HUMAN relationship: has_participant CCO:B0057088 ! SYDE1_HUMAN relationship: has_participant CCO:B0057089 ! Q6ZW62_HUMAN relationship: has_participant CCO:B0057092 ! RAPH1_HUMAN relationship: has_participant CCO:B0057094 ! Q711G2_HUMAN relationship: has_participant CCO:B0057095 ! Q712M9_HUMAN relationship: has_participant CCO:B0057099 ! Q71U75_HUMAN relationship: has_participant CCO:B0057107 ! Q76LB3_HUMAN relationship: has_participant CCO:B0057110 ! Q7KYU8_HUMAN relationship: has_participant CCO:B0057123 ! GRP2_HUMAN relationship: has_participant CCO:B0057125 ! T2R42_HUMAN relationship: has_participant CCO:B0057139 ! TS1R3_HUMAN relationship: has_participant CCO:B0057140 ! TS1R1_HUMAN relationship: has_participant CCO:B0057142 ! Q7Z2I8_HUMAN relationship: has_participant CCO:B0057153 ! 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Q86SG0_HUMAN relationship: has_participant CCO:B0057226 ! Q86SG9_HUMAN relationship: has_participant CCO:B0057227 ! Q86SI5_HUMAN relationship: has_participant CCO:B0057229 ! MRGRG_HUMAN relationship: has_participant CCO:B0057230 ! Q86SP4_HUMAN relationship: has_participant CCO:B0057231 ! GP149_HUMAN relationship: has_participant CCO:B0057232 ! EMR4_HUMAN relationship: has_participant CCO:B0057233 ! GP123_HUMAN relationship: has_participant CCO:B0057243 ! Q86U13_HUMAN relationship: has_participant CCO:B0057258 ! Q86UY3_HUMAN relationship: has_participant CCO:B0057281 ! SKAP1_HUMAN relationship: has_participant CCO:B0057288 ! Q86XI1_HUMAN relationship: has_participant CCO:B0057293 ! TCAM2_HUMAN relationship: has_participant CCO:B0057297 ! Q86XV6_HUMAN relationship: has_participant CCO:B0057300 ! GPR97_HUMAN relationship: has_participant CCO:B0057302 ! Q86YC4_HUMAN relationship: has_participant CCO:B0057309 ! GPSM1_HUMAN relationship: has_participant CCO:B0057311 ! RAB43_HUMAN relationship: has_participant CCO:B0057314 ! PLCZ1_HUMAN relationship: has_participant CCO:B0057316 ! Q86YZ7_HUMAN relationship: has_participant CCO:B0057320 ! RHPN2_HUMAN relationship: has_participant CCO:B0057325 ! NPAS4_HUMAN relationship: has_participant CCO:B0057327 ! Q8IUT4_HUMAN relationship: has_participant CCO:B0057331 ! Q8IUY2_HUMAN relationship: has_participant CCO:B0057333 ! Q8IV15_HUMAN relationship: has_participant CCO:B0057335 ! UN5CL_HUMAN relationship: has_participant CCO:B0057341 ! PCP2_HUMAN relationship: has_participant CCO:B0057343 ! TIAM2_HUMAN relationship: has_participant CCO:B0057358 ! TEX2_HUMAN relationship: has_participant CCO:B0057361 ! GP125_HUMAN relationship: has_participant CCO:B0057370 ! Q8IXD9_HUMAN relationship: has_participant CCO:B0057371 ! Q8IXE0_HUMAN relationship: has_participant CCO:B0057372 ! OR4N5_HUMAN relationship: has_participant CCO:B0057375 ! NPAS3_HUMAN relationship: has_participant CCO:B0057382 ! Q8IY43_HUMAN relationship: has_participant CCO:B0057400 ! RTKN2_HUMAN relationship: has_participant CCO:B0057402 ! GP116_HUMAN relationship: has_participant CCO:B0057403 ! GP115_HUMAN relationship: has_participant CCO:B0057404 ! GP114_HUMAN relationship: has_participant CCO:B0057405 ! GP113_HUMAN relationship: has_participant CCO:B0057406 ! GP111_HUMAN relationship: has_participant CCO:B0057407 ! UNC5B_HUMAN relationship: has_participant CCO:B0057413 ! Q8N0W0_HUMAN relationship: has_participant CCO:B0057414 ! Q8N0W1_HUMAN relationship: has_participant CCO:B0057415 ! Q8N0X1_HUMAN relationship: has_participant CCO:B0057417 ! OR4N4_HUMAN relationship: has_participant CCO:B0057418 ! OR8I2_HUMAN relationship: has_participant CCO:B0057423 ! LIRA2_HUMAN relationship: has_participant CCO:B0057424 ! Q8N164_HUMAN relationship: has_participant CCO:B0057438 ! RHG24_HUMAN relationship: has_participant CCO:B0057453 ! OR2LD_HUMAN relationship: has_participant CCO:B0057455 ! PLCD3_HUMAN relationship: has_participant CCO:B0057464 ! SFRP1_HUMAN relationship: has_participant CCO:B0057477 ! Q8N5M2_HUMAN relationship: has_participant CCO:B0057479 ! M4A15_HUMAN relationship: has_participant CCO:B0057483 ! OR2C3_HUMAN relationship: has_participant CCO:B0057486 ! IGSF1_HUMAN relationship: has_participant CCO:B0057487 ! LIRA3_HUMAN relationship: has_participant CCO:B0057491 ! Q8N6P3_HUMAN relationship: has_participant CCO:B0057493 ! Q8N6U1_HUMAN relationship: has_participant CCO:B0057494 ! GP161_HUMAN relationship: has_participant CCO:B0057507 ! Q8N7S5_HUMAN relationship: has_participant CCO:B0057509 ! Q8N7X7_HUMAN relationship: has_participant CCO:B0057551 ! Q8NB10_HUMAN relationship: has_participant CCO:B0057567 ! Q8NCH7_HUMAN relationship: has_participant CCO:B0057570 ! KCNH5_HUMAN relationship: has_participant CCO:B0057576 ! Q8NDC7_HUMAN relationship: has_participant CCO:B0057581 ! GPR26_HUMAN relationship: has_participant CCO:B0057595 ! NFAM1_HUMAN relationship: has_participant CCO:B0057603 ! RAI3_HUMAN relationship: has_participant CCO:B0057604 ! PKR2_HUMAN relationship: has_participant CCO:B0057606 ! GP156_HUMAN relationship: has_participant CCO:B0057610 ! VN1R2_HUMAN relationship: has_participant CCO:B0057615 ! Q8NG71_HUMAN relationship: has_participant CCO:B0057616 ! Q8NG73_HUMAN relationship: has_participant CCO:B0057617 ! O2T33_HUMAN relationship: has_participant CCO:B0057618 ! O2T12_HUMAN relationship: has_participant CCO:B0057619 ! OR2L5_HUMAN relationship: has_participant CCO:B0057620 ! OR2M7_HUMAN relationship: has_participant CCO:B0057621 ! OR2M3_HUMAN relationship: has_participant CCO:B0057622 ! O2AK2_HUMAN relationship: has_participant CCO:B0057623 ! OR2L3_HUMAN relationship: has_participant CCO:B0057624 ! Q8NG91_HUMAN relationship: has_participant CCO:B0057625 ! O13H1_HUMAN relationship: has_participant CCO:B0057626 ! OR7G3_HUMAN relationship: has_participant CCO:B0057627 ! OR2Z1_HUMAN relationship: has_participant CCO:B0057628 ! OR7D4_HUMAN relationship: has_participant CCO:B0057629 ! OR7G1_HUMAN relationship: has_participant CCO:B0057630 ! OR1M1_HUMAN relationship: has_participant CCO:B0057631 ! OR7A2_HUMAN relationship: has_participant CCO:B0057632 ! Q8NGA3_HUMAN relationship: has_participant CCO:B0057634 ! O10H4_HUMAN relationship: has_participant CCO:B0057635 ! O10H5_HUMAN relationship: has_participant CCO:B0057636 ! O4F17_HUMAN relationship: has_participant CCO:B0057639 ! OR4C5_HUMAN relationship: has_participant CCO:B0057640 ! OR4S1_HUMAN relationship: has_participant CCO:B0057641 ! Q8NGB5_HUMAN relationship: has_participant CCO:B0057642 ! OR4M2_HUMAN relationship: has_participant CCO:B0057643 ! O4F15_HUMAN relationship: has_participant CCO:B0057644 ! OR4F6_HUMAN relationship: has_participant CCO:B0057645 ! OR4E2_HUMAN relationship: has_participant CCO:B0057646 ! O10G2_HUMAN relationship: has_participant CCO:B0057647 ! O10G3_HUMAN relationship: has_participant CCO:B0057648 ! OR6J1_HUMAN relationship: has_participant CCO:B0057649 ! O11H6_HUMAN relationship: has_participant CCO:B0057650 ! O11H7_HUMAN relationship: has_participant CCO:B0057651 ! O11H4_HUMAN relationship: has_participant CCO:B0057652 ! OR4M1_HUMAN relationship: has_participant CCO:B0057653 ! OR4N2_HUMAN relationship: has_participant CCO:B0057654 ! OR4K2_HUMAN relationship: has_participant CCO:B0057655 ! OR4K5_HUMAN relationship: has_participant CCO:B0057656 ! OR4K1_HUMAN relationship: has_participant CCO:B0057657 ! OR4KE_HUMAN relationship: has_participant CCO:B0057658 ! O10AD_HUMAN relationship: has_participant CCO:B0057659 ! OR6C4_HUMAN relationship: has_participant CCO:B0057660 ! O2AP1_HUMAN relationship: has_participant CCO:B0057661 ! O10A7_HUMAN relationship: has_participant CCO:B0057662 ! Q8NGE6_HUMAN relationship: has_participant CCO:B0057663 ! OR4D9_HUMAN relationship: has_participant CCO:B0057664 ! Q8NGF2_HUMAN relationship: has_participant CCO:B0057665 ! O51D1_HUMAN relationship: has_participant CCO:B0057666 ! O10W1_HUMAN relationship: has_participant CCO:B0057667 ! OR4B1_HUMAN relationship: has_participant CCO:B0057668 ! OR4X2_HUMAN relationship: has_participant CCO:B0057669 ! OR8J3_HUMAN relationship: has_participant CCO:B0057670 ! OR8J2_HUMAN relationship: has_participant CCO:B0057671 ! OR8K1_HUMAN relationship: has_participant CCO:B0057672 ! OR8BC_HUMAN relationship: has_participant CCO:B0057673 ! OR8B3_HUMAN relationship: has_participant CCO:B0057674 ! Q8NGG9_HUMAN relationship: has_participant CCO:B0057675 ! Q8NGH2_HUMAN relationship: has_participant CCO:B0057676 ! O52E4_HUMAN relationship: has_participant CCO:B0057677 ! O52N2_HUMAN relationship: has_participant CCO:B0057678 ! O56B2_HUMAN relationship: has_participant CCO:B0057679 ! O52N4_HUMAN relationship: has_participant CCO:B0057680 ! O56B1_HUMAN relationship: has_participant CCO:B0057681 ! OR4DB_HUMAN relationship: has_participant CCO:B0057682 ! Q8NGI5_HUMAN relationship: has_participant CCO:B0057683 ! OR4DA_HUMAN relationship: has_participant CCO:B0057684 ! O10V1_HUMAN relationship: has_participant CCO:B0057685 ! O5AN1_HUMAN relationship: has_participant CCO:B0057686 ! OR5A2_HUMAN relationship: has_participant CCO:B0057687 ! OR5A1_HUMAN relationship: has_participant CCO:B0057688 ! OR4D6_HUMAN relationship: has_participant CCO:B0057689 ! O52E1_HUMAN relationship: has_participant CCO:B0057690 ! O52E2_HUMAN relationship: has_participant CCO:B0057691 ! O51L1_HUMAN relationship: has_participant CCO:B0057692 ! O51A4_HUMAN relationship: has_participant CCO:B0057693 ! O51A2_HUMAN relationship: has_participant CCO:B0057694 ! O51S1_HUMAN relationship: has_participant CCO:B0057695 ! O51G2_HUMAN relationship: has_participant CCO:B0057696 ! O51G1_HUMAN relationship: has_participant CCO:B0057697 ! O52B4_HUMAN relationship: has_participant CCO:B0057698 ! O52K2_HUMAN relationship: has_participant CCO:B0057699 ! O52K1_HUMAN relationship: has_participant CCO:B0057700 ! O52M1_HUMAN relationship: has_participant CCO:B0057701 ! O52I1_HUMAN relationship: has_participant CCO:B0057702 ! Q8NGK8_HUMAN relationship: has_participant CCO:B0057703 ! OR5DG_HUMAN relationship: has_participant CCO:B0057704 ! OR5DI_HUMAN relationship: has_participant CCO:B0057705 ! OR5DE_HUMAN relationship: has_participant CCO:B0057706 ! OR5DD_HUMAN relationship: has_participant CCO:B0057707 ! Q8NGL5_HUMAN relationship: has_participant CCO:B0057708 ! O4A15_HUMAN relationship: has_participant CCO:B0057709 ! OR4P4_HUMAN relationship: has_participant CCO:B0057710 ! OR4CG_HUMAN relationship: has_participant CCO:B0057711 ! Q8NGM0_HUMAN relationship: has_participant CCO:B0057712 ! OR4CF_HUMAN relationship: has_participant CCO:B0057713 ! Q8NGM3_HUMAN relationship: has_participant CCO:B0057714 ! Q8NGM4_HUMAN relationship: has_participant CCO:B0057715 ! Q8NGM5_HUMAN relationship: has_participant CCO:B0057716 ! Q8NGM6_HUMAN relationship: has_participant CCO:B0057717 ! Q8NGM7_HUMAN relationship: has_participant CCO:B0057718 ! OR4D5_HUMAN relationship: has_participant CCO:B0057719 ! OR6T1_HUMAN relationship: has_participant CCO:B0057720 ! O10G4_HUMAN relationship: has_participant CCO:B0057721 ! O10G9_HUMAN relationship: has_participant CCO:B0057722 ! O10G8_HUMAN relationship: has_participant CCO:B0057723 ! O10G7_HUMAN relationship: has_participant CCO:B0057724 ! O10D4_HUMAN relationship: has_participant CCO:B0057725 ! OR4A4_HUMAN relationship: has_participant CCO:B0057726 ! Q8NGN9_HUMAN relationship: has_participant CCO:B0057727 ! OR4CD_HUMAN relationship: has_participant CCO:B0057728 ! OR8J1_HUMAN relationship: has_participant CCO:B0057729 ! OR5M9_HUMAN relationship: has_participant CCO:B0057730 ! OR5M3_HUMAN relationship: has_participant CCO:B0057731 ! Q8NGP5_HUMAN relationship: has_participant CCO:B0057732 ! OR5M8_HUMAN relationship: has_participant CCO:B0057733 ! Q8NGP7_HUMAN relationship: has_participant CCO:B0057734 ! OR5M1_HUMAN relationship: has_participant CCO:B0057735 ! OR6Q1_HUMAN relationship: has_participant CCO:B0057736 ! O10Q1_HUMAN relationship: has_participant CCO:B0057737 ! OR9Q1_HUMAN relationship: has_participant CCO:B0057738 ! Q8NGQ7_HUMAN relationship: has_participant CCO:B0057739 ! OR1K1_HUMAN relationship: has_participant CCO:B0057740 ! OR1L4_HUMAN relationship: has_participant CCO:B0057741 ! OR1B1_HUMAN relationship: has_participant CCO:B0057742 ! OR1L8_HUMAN relationship: has_participant CCO:B0057743 ! OR1N1_HUMAN relationship: has_participant CCO:B0057744 ! OR1J4_HUMAN relationship: has_participant CCO:B0057745 ! OR1J2_HUMAN relationship: has_participant CCO:B0057746 ! OR1J1_HUMAN relationship: has_participant CCO:B0057747 ! O13F1_HUMAN relationship: has_participant CCO:B0057748 ! O13C4_HUMAN relationship: has_participant CCO:B0057749 ! O13C8_HUMAN relationship: has_participant CCO:B0057750 ! O13C5_HUMAN relationship: has_participant CCO:B0057751 ! O13C2_HUMAN relationship: has_participant CCO:B0057752 ! O13C9_HUMAN relationship: has_participant CCO:B0057753 ! OR2K1_HUMAN relationship: has_participant CCO:B0057754 ! O13J1_HUMAN relationship: has_participant CCO:B0057755 ! OR9A2_HUMAN relationship: has_participant CCO:B0057756 ! O2A12_HUMAN relationship: has_participant CCO:B0057757 ! OR2A1_HUMAN relationship: has_participant CCO:B0057758 ! Q8NGU0_HUMAN relationship: has_participant CCO:B0057759 ! OR9A1_HUMAN relationship: has_participant CCO:B0057760 ! OR9A4_HUMAN relationship: has_participant CCO:B0057762 ! OR2I1_HUMAN relationship: has_participant CCO:B0057763 ! Q8NGU6_HUMAN relationship: has_participant CCO:B0057764 ! Q8NGU7_HUMAN relationship: has_participant CCO:B0057765 ! GP150_HUMAN relationship: has_participant CCO:B0057766 ! OR2Y1_HUMAN relationship: has_participant CCO:B0057768 ! CSRL1_HUMAN relationship: has_participant CCO:B0057769 ! OR6B3_HUMAN relationship: has_participant CCO:B0057771 ! Q8NGW3_HUMAN relationship: has_participant CCO:B0057772 ! O11L1_HUMAN relationship: has_participant CCO:B0057773 ! O2T34_HUMAN relationship: has_participant CCO:B0057774 ! O2T35_HUMAN relationship: has_participant CCO:B0057775 ! O10T2_HUMAN relationship: has_participant CCO:B0057776 ! Q8NGX4_HUMAN relationship: has_participant CCO:B0057777 ! O10K1_HUMAN relationship: has_participant CCO:B0057778 ! Q8NGX7_HUMAN relationship: has_participant CCO:B0057779 ! OR6Y1_HUMAN relationship: has_participant CCO:B0057780 ! OR6P1_HUMAN relationship: has_participant CCO:B0057781 ! O10X1_HUMAN relationship: has_participant CCO:B0057782 ! O10Z1_HUMAN relationship: has_participant CCO:B0057783 ! OR6K2_HUMAN relationship: has_participant CCO:B0057784 ! Q8NGY4_HUMAN relationship: has_participant CCO:B0057785 ! OR6N1_HUMAN relationship: has_participant CCO:B0057786 ! OR6N2_HUMAN relationship: has_participant CCO:B0057787 ! O10J6_HUMAN relationship: has_participant CCO:B0057788 ! OR2L8_HUMAN relationship: has_participant CCO:B0057789 ! O2AJ1_HUMAN relationship: has_participant CCO:B0057790 ! O14K1_HUMAN relationship: has_participant CCO:B0057791 ! O13G1_HUMAN relationship: has_participant CCO:B0057792 ! OR2G3_HUMAN relationship: has_participant CCO:B0057793 ! OR2G2_HUMAN relationship: has_participant CCO:B0057794 ! OR6F1_HUMAN relationship: has_participant CCO:B0057795 ! O2T10_HUMAN relationship: has_participant CCO:B0057796 ! OR2T4_HUMAN relationship: has_participant CCO:B0057797 ! O2T11_HUMAN relationship: has_participant CCO:B0057798 ! O2T29_HUMAN relationship: has_participant CCO:B0057799 ! OR2T3_HUMAN relationship: has_participant CCO:B0057800 ! O2T27_HUMAN relationship: has_participant CCO:B0057801 ! OR4Q3_HUMAN relationship: has_participant CCO:B0057802 ! OR1P1_HUMAN relationship: has_participant CCO:B0057803 ! O11H2_HUMAN relationship: has_participant CCO:B0057804 ! O10AC_HUMAN relationship: has_participant CCO:B0057805 ! OR8S1_HUMAN relationship: has_participant CCO:B0057806 ! Q8NH11_HUMAN relationship: has_participant CCO:B0057807 ! Q8NH14_HUMAN relationship: has_participant CCO:B0057808 ! OR2L2_HUMAN relationship: has_participant CCO:B0057809 ! Q8NH17_HUMAN relationship: has_participant CCO:B0057810 ! O10AG_HUMAN relationship: has_participant CCO:B0057811 ! OR4F5_HUMAN relationship: has_participant CCO:B0057813 ! Q8NH23_HUMAN relationship: has_participant CCO:B0057814 ! Q8NH24_HUMAN relationship: has_participant CCO:B0057816 ! Q8NH29_HUMAN relationship: has_participant CCO:B0057817 ! Q8NH32_HUMAN relationship: has_participant CCO:B0057818 ! Q8NH33_HUMAN relationship: has_participant CCO:B0057819 ! Q8NH36_HUMAN relationship: has_participant CCO:B0057820 ! OR4C3_HUMAN relationship: has_participant CCO:B0057821 ! Q8NH38_HUMAN relationship: has_participant CCO:B0057822 ! OR4KD_HUMAN relationship: has_participant CCO:B0057823 ! OR4L1_HUMAN relationship: has_participant CCO:B0057824 ! Q8NH44_HUMAN relationship: has_participant CCO:B0057825 ! Q8NH47_HUMAN relationship: has_participant CCO:B0057826 ! OR4X1_HUMAN relationship: has_participant CCO:B0057827 ! OR8K3_HUMAN relationship: has_participant CCO:B0057828 ! O52N1_HUMAN relationship: has_participant CCO:B0057829 ! O56A3_HUMAN relationship: has_participant CCO:B0057830 ! O52E5_HUMAN relationship: has_participant CCO:B0057831 ! O52N5_HUMAN relationship: has_participant CCO:B0057832 ! O52P1_HUMAN relationship: has_participant CCO:B0057833 ! Q8NH58_HUMAN relationship: has_participant CCO:B0057834 ! O51Q1_HUMAN relationship: has_participant CCO:B0057835 ! O52J3_HUMAN relationship: has_participant CCO:B0057836 ! Q8NH62_HUMAN relationship: has_participant CCO:B0057837 ! O51H1_HUMAN relationship: has_participant CCO:B0057838 ! O51A7_HUMAN relationship: has_participant CCO:B0057839 ! Q8NH66_HUMAN relationship: has_participant CCO:B0057840 ! Q8NH68_HUMAN relationship: has_participant CCO:B0057841 ! O4A16_HUMAN relationship: has_participant CCO:B0057842 ! Q8NH71_HUMAN relationship: has_participant CCO:B0057843 ! OR4C6_HUMAN relationship: has_participant CCO:B0057844 ! OR4S2_HUMAN relationship: has_participant CCO:B0057845 ! O10A6_HUMAN relationship: has_participant CCO:B0057846 ! Q8NH75_HUMAN relationship: has_participant CCO:B0057847 ! O56B4_HUMAN relationship: has_participant CCO:B0057848 ! Q8NH77_HUMAN relationship: has_participant CCO:B0057849 ! Q8NH78_HUMAN relationship: has_participant CCO:B0057850 ! OR6X1_HUMAN relationship: has_participant CCO:B0057851 ! O10D3_HUMAN relationship: has_participant CCO:B0057852 ! O10G6_HUMAN relationship: has_participant CCO:B0057853 ! Q8NH82_HUMAN relationship: has_participant CCO:B0057854 ! OR4A5_HUMAN relationship: has_participant CCO:B0057855 ! Q8NH84_HUMAN relationship: has_participant CCO:B0057856 ! Q8NH86_HUMAN relationship: has_participant CCO:B0057857 ! OR9G1_HUMAN relationship: has_participant CCO:B0057858 ! Q8NH88_HUMAN relationship: has_participant CCO:B0057859 ! OR1L3_HUMAN relationship: has_participant CCO:B0057860 ! YI035_HUMAN relationship: has_participant CCO:B0057861 ! O2AE1_HUMAN relationship: has_participant CCO:B0057862 ! OR2W6_HUMAN relationship: has_participant CCO:B0057863 ! Q8NHA7_HUMAN relationship: has_participant CCO:B0057864 ! OR1FC_HUMAN relationship: has_participant CCO:B0057866 ! OR2V1_HUMAN relationship: has_participant CCO:B0057867 ! Q8NHB3_HUMAN relationship: has_participant CCO:B0057868 ! Q8NHC2_HUMAN relationship: has_participant CCO:B0057869 ! Q8NHC3_HUMAN relationship: has_participant CCO:B0057870 ! O10J5_HUMAN relationship: has_participant CCO:B0057871 ! O14AG_HUMAN relationship: has_participant CCO:B0057872 ! O14L1_HUMAN relationship: has_participant CCO:B0057873 ! O14CZ_HUMAN relationship: has_participant CCO:B0057874 ! OR2T6_HUMAN relationship: has_participant CCO:B0057875 ! LIRB4_HUMAN relationship: has_participant CCO:B0057882 ! Q8NI49_HUMAN relationship: has_participant CCO:B0057883 ! Q8NI50_HUMAN relationship: has_participant CCO:B0057884 ! ANGL6_HUMAN relationship: has_participant CCO:B0057894 ! STML3_HUMAN relationship: has_participant CCO:B0057896 ! RIN3_HUMAN relationship: has_participant CCO:B0057913 ! O51E1_HUMAN relationship: has_participant CCO:B0057917 ! PKR1_HUMAN relationship: has_participant CCO:B0057918 ! RHPN1_HUMAN relationship: has_participant CCO:B0057923 ! Q8TDA2_HUMAN relationship: has_participant CCO:B0057929 ! Q8TDP6_HUMAN relationship: has_participant CCO:B0057930 ! Q8TDP8_HUMAN relationship: has_participant CCO:B0057932 ! G109A_HUMAN relationship: has_participant CCO:B0057933 ! OXER1_HUMAN relationship: has_participant CCO:B0057934 ! MRGRD_HUMAN relationship: has_participant CCO:B0057935 ! GP152_HUMAN relationship: has_participant CCO:B0057937 ! Q8TDT9_HUMAN relationship: has_participant CCO:B0057938 ! VNRL4_HUMAN relationship: has_participant CCO:B0057939 ! GPBAR_HUMAN relationship: has_participant CCO:B0057940 ! RL3R2_HUMAN relationship: has_participant CCO:B0057941 ! GP151_HUMAN relationship: has_participant CCO:B0057943 ! GP148_HUMAN relationship: has_participant CCO:B0057944 ! GP119_HUMAN relationship: has_participant CCO:B0057947 ! MICA1_HUMAN relationship: has_participant CCO:B0057950 ! TS1R2_HUMAN relationship: has_participant CCO:B0057952 ! Q8TEA3_HUMAN relationship: has_participant CCO:B0057956 ! RPGF6_HUMAN relationship: has_participant CCO:B0057959 ! PP4R1_HUMAN relationship: has_participant CCO:B0057968 ! GRK7_HUMAN relationship: has_participant CCO:B0057986 ! DEP1B_HUMAN relationship: has_participant CCO:B0057993 ! PPR1C_HUMAN relationship: has_participant CCO:B0058001 ! Q8WW76_HUMAN relationship: has_participant CCO:B0058002 ! ITLN1_HUMAN relationship: has_participant CCO:B0058006 ! ITLN2_HUMAN relationship: has_participant CCO:B0058009 ! EDAD_HUMAN relationship: has_participant CCO:B0058012 ! Q8WX98_HUMAN relationship: has_participant CCO:B0058015 ! CSKI1_HUMAN relationship: has_participant CCO:B0058018 ! GPR98_HUMAN relationship: has_participant CCO:B0058036 ! Q8WXZ9_HUMAN relationship: has_participant CCO:B0058041 ! BMAL2_HUMAN relationship: has_participant CCO:B0058042 ! CNTP5_HUMAN relationship: has_participant CCO:B0058047 ! RIN2_HUMAN relationship: has_participant CCO:B0058052 ! OR8D1_HUMAN relationship: has_participant CCO:B0058053 ! OR5P2_HUMAN relationship: has_participant CCO:B0058054 ! OR5P3_HUMAN relationship: has_participant CCO:B0058055 ! RPGF4_HUMAN relationship: has_participant CCO:B0058056 ! OR1E3_HUMAN relationship: has_participant CCO:B0058075 ! HMHA1_HUMAN relationship: has_participant CCO:B0058076 ! LPAR1_HUMAN relationship: has_participant CCO:B0058077 ! FAN_HUMAN relationship: has_participant CCO:B0058082 ! NEUG_HUMAN relationship: has_participant CCO:B0058084 ! ESR2_HUMAN relationship: has_participant CCO:B0058089 ! TENR_HUMAN relationship: has_participant CCO:B0058093 ! STAM1_HUMAN relationship: has_participant CCO:B0058100 ! SHIP1_HUMAN relationship: has_participant CCO:B0058102 ! EDA_HUMAN relationship: has_participant CCO:B0058103 ! TANK_HUMAN relationship: has_participant CCO:B0058104 ! KIFA3_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN relationship: has_participant CCO:B0058109 ! OSTF1_HUMAN relationship: has_participant CCO:B0058110 ! CDS1_HUMAN relationship: has_participant CCO:B0058113 ! Q92942_HUMAN relationship: has_participant CCO:B0058118 ! DVL3_HUMAN relationship: has_participant CCO:B0058119 ! Q93003_HUMAN relationship: has_participant CCO:B0058121 ! TNR25_HUMAN relationship: has_participant CCO:B0058122 ! P2RX5_HUMAN relationship: has_participant CCO:B0058125 ! WNT8B_HUMAN relationship: has_participant CCO:B0058129 ! KISSR_HUMAN relationship: has_participant CCO:B0058135 ! TAAR8_HUMAN relationship: has_participant CCO:B0058137 ! TRI63_HUMAN relationship: has_participant CCO:B0058141 ! MCHR2_HUMAN relationship: has_participant CCO:B0058174 ! Q96C06_HUMAN relationship: has_participant CCO:B0058177 ! ROP1L_HUMAN relationship: has_participant CCO:B0058180 ! Q96C95_HUMAN relationship: has_participant CCO:B0058182 ! GP146_HUMAN relationship: has_participant CCO:B0058196 ! M4A6E_HUMAN relationship: has_participant CCO:B0058211 ! THOC1_HUMAN relationship: has_participant CCO:B0058213 ! P2Y11_HUMAN relationship: has_participant CCO:B0058222 ! MS4A3_HUMAN relationship: has_participant CCO:B0058228 ! Q96II5_HUMAN relationship: has_participant CCO:B0058236 ! M4A14_HUMAN relationship: has_participant CCO:B0058240 ! RADIL_HUMAN relationship: has_participant CCO:B0058248 ! M4A4A_HUMAN relationship: has_participant CCO:B0058255 ! GP128_HUMAN relationship: has_participant CCO:B0058259 ! O10C1_HUMAN relationship: has_participant CCO:B0058262 ! Q96KP3_HUMAN relationship: has_participant CCO:B0058265 ! KCNH8_HUMAN relationship: has_participant CCO:B0058267 ! SNX27_HUMAN relationship: has_participant CCO:B0058268 ! MRGX4_HUMAN relationship: has_participant CCO:B0058269 ! MRGX3_HUMAN relationship: has_participant CCO:B0058270 ! MRGX2_HUMAN relationship: has_participant CCO:B0058271 ! MRGX1_HUMAN relationship: has_participant CCO:B0058280 ! YK021_HUMAN relationship: has_participant CCO:B0058281 ! Q96M80_HUMAN relationship: has_participant CCO:B0058313 ! CNT3B_HUMAN relationship: has_participant CCO:B0058316 ! NALP3_HUMAN relationship: has_participant CCO:B0058319 ! Q96P62_HUMAN relationship: has_participant CCO:B0058320 ! QRFPR_HUMAN relationship: has_participant CCO:B0058321 ! GP101_HUMAN relationship: has_participant CCO:B0058322 ! GPR82_HUMAN relationship: has_participant CCO:B0058323 ! OXGR1_HUMAN relationship: has_participant CCO:B0058324 ! GPR78_HUMAN relationship: has_participant CCO:B0058326 ! GNRR2_HUMAN relationship: has_participant CCO:B0058329 ! GP124_HUMAN relationship: has_participant CCO:B0058331 ! INP4A_HUMAN relationship: has_participant CCO:B0058333 ! M4A4E_HUMAN relationship: has_participant CCO:B0058334 ! M4A10_HUMAN relationship: has_participant CCO:B0058346 ! Q96PV9_HUMAN relationship: has_participant CCO:B0058349 ! ASB2_HUMAN relationship: has_participant CCO:B0058359 ! OR2M4_HUMAN relationship: has_participant CCO:B0058360 ! OR2M2_HUMAN relationship: has_participant CCO:B0058361 ! OR2V2_HUMAN relationship: has_participant CCO:B0058362 ! OR2A7_HUMAN relationship: has_participant CCO:B0058363 ! O2A14_HUMAN relationship: has_participant CCO:B0058364 ! OR2A5_HUMAN relationship: has_participant CCO:B0058365 ! O14A2_HUMAN relationship: has_participant CCO:B0058366 ! OR4CC_HUMAN relationship: has_participant CCO:B0058367 ! OR4F4_HUMAN relationship: has_participant CCO:B0058368 ! OR4K3_HUMAN relationship: has_participant CCO:B0058369 ! OR1F2_HUMAN relationship: has_participant CCO:B0058370 ! OR7D2_HUMAN relationship: has_participant CCO:B0058371 ! OR8B2_HUMAN relationship: has_participant CCO:B0058372 ! OR6C1_HUMAN relationship: has_participant CCO:B0058373 ! O52E6_HUMAN relationship: has_participant CCO:B0058375 ! PASK_HUMAN relationship: has_participant CCO:B0058376 ! NR1H4_HUMAN relationship: has_participant CCO:B0058377 ! TAAR6_HUMAN relationship: has_participant CCO:B0058378 ! TAAR9_HUMAN relationship: has_participant CCO:B0058379 ! TAAR1_HUMAN relationship: has_participant CCO:B0058385 ! KS6C1_HUMAN relationship: has_participant CCO:B0058401 ! PP16B_HUMAN relationship: has_participant CCO:B0058406 ! Q99061_HUMAN relationship: has_participant CCO:B0058407 ! CSF3R_HUMAN relationship: has_participant CCO:B0058415 ! STAC_HUMAN relationship: has_participant CCO:B0058417 ! CENG1_HUMAN relationship: has_participant CCO:B0058418 ! S1PR3_HUMAN relationship: has_participant CCO:B0058422 ! GPER_HUMAN relationship: has_participant CCO:B0058423 ! P2RX4_HUMAN relationship: has_participant CCO:B0058426 ! RIT2_HUMAN relationship: has_participant CCO:B0058438 ! GPR20_HUMAN relationship: has_participant CCO:B0058439 ! GPR21_HUMAN relationship: has_participant CCO:B0058440 ! GPR22_HUMAN relationship: has_participant CCO:B0058443 ! DOK1_HUMAN relationship: has_participant CCO:B0058444 ! MCHR1_HUMAN relationship: has_participant CCO:B0058445 ! KI2L4_HUMAN relationship: has_participant CCO:B0058446 ! SMAD5_HUMAN relationship: has_participant CCO:B0058448 ! CCL19_HUMAN relationship: has_participant CCO:B0058450 ! MGST2_HUMAN relationship: has_participant CCO:B0058451 ! NPAS1_HUMAN relationship: has_participant CCO:B0058454 ! CML1_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058463 ! ATF6B_HUMAN relationship: has_participant CCO:B0058466 ! GDF15_HUMAN relationship: has_participant CCO:B0058468 ! DPYL5_HUMAN relationship: has_participant CCO:B0058469 ! P2Y13_HUMAN relationship: has_participant CCO:B0058489 ! PLCD4_HUMAN relationship: has_participant CCO:B0058496 ! RHG09_HUMAN relationship: has_participant CCO:B0058510 ! RTKN_HUMAN relationship: has_participant CCO:B0058525 ! TRAF4_HUMAN relationship: has_participant CCO:B0058532 ! TRAIP_HUMAN relationship: has_participant CCO:B0058533 ! Q9BWG3_HUMAN relationship: has_participant CCO:B0058548 ! LGR4_HUMAN relationship: has_participant CCO:B0058549 ! GPR81_HUMAN relationship: has_participant CCO:B0058550 ! GP174_HUMAN relationship: has_participant CCO:B0058551 ! VN1R3_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN relationship: has_participant CCO:B0058565 ! EMR3_HUMAN relationship: has_participant CCO:B0058566 ! M4A8B_HUMAN relationship: has_participant CCO:B0058567 ! GPR87_HUMAN relationship: has_participant CCO:B0058572 ! ANGL4_HUMAN relationship: has_participant CCO:B0058583 ! TRI54_HUMAN relationship: has_participant CCO:B0058584 ! TRI55_HUMAN relationship: has_participant CCO:B0058589 ! Q9BZ69_HUMAN relationship: has_participant CCO:B0058590 ! CNTP3_HUMAN relationship: has_participant CCO:B0058600 ! GPR63_HUMAN relationship: has_participant CCO:B0058601 ! GPR62_HUMAN relationship: has_participant CCO:B0058602 ! GPR61_HUMAN relationship: has_participant CCO:B0058610 ! CD244_HUMAN relationship: has_participant CCO:B0058611 ! ROP1B_HUMAN relationship: has_participant CCO:B0058620 ! K1688_HUMAN relationship: has_participant CCO:B0058624 ! OR2B2_HUMAN relationship: has_participant CCO:B0058625 ! OR2H1_HUMAN relationship: has_participant CCO:B0058626 ! OR2J1_HUMAN relationship: has_participant CCO:B0058627 ! O11A1_HUMAN relationship: has_participant CCO:B0058629 ! GPR88_HUMAN relationship: has_participant CCO:B0058630 ! VN1R1_HUMAN relationship: has_participant CCO:B0058632 ! NMUR2_HUMAN relationship: has_participant CCO:B0058633 ! NPFF1_HUMAN relationship: has_participant CCO:B0058651 ! BRD8_HUMAN relationship: has_participant CCO:B0058653 ! WWP1_HUMAN relationship: has_participant CCO:B0058663 ! LPAR5_HUMAN relationship: has_participant CCO:B0058667 ! OPN3_HUMAN relationship: has_participant CCO:B0058668 ! O2AG1_HUMAN relationship: has_participant CCO:B0058669 ! O10A5_HUMAN relationship: has_participant CCO:B0058670 ! O10A2_HUMAN relationship: has_participant CCO:B0058671 ! O10A4_HUMAN relationship: has_participant CCO:B0058672 ! OR2D2_HUMAN relationship: has_participant CCO:B0058673 ! S1PR5_HUMAN relationship: has_participant CCO:B0058675 ! P2Y12_HUMAN relationship: has_participant CCO:B0058676 ! KCNH6_HUMAN relationship: has_participant CCO:B0058678 ! O51E2_HUMAN relationship: has_participant CCO:B0058681 ! O52A5_HUMAN relationship: has_participant CCO:B0058682 ! Q9H2C6_HUMAN relationship: has_participant CCO:B0058683 ! O51V1_HUMAN relationship: has_participant CCO:B0058689 ! M4A6A_HUMAN relationship: has_participant CCO:B0058694 ! O51B5_HUMAN relationship: has_participant CCO:B0058695 ! O51B6_HUMAN relationship: has_participant CCO:B0058696 ! O51M1_HUMAN relationship: has_participant CCO:B0058697 ! O51J1_HUMAN relationship: has_participant CCO:B0058698 ! O51I1_HUMAN relationship: has_participant CCO:B0058699 ! O51I2_HUMAN relationship: has_participant CCO:B0058700 ! Q9H345_HUMAN relationship: has_participant CCO:B0058701 ! O52D1_HUMAN relationship: has_participant CCO:B0058705 ! TXND1_HUMAN relationship: has_participant CCO:B0058706 ! HRH4_HUMAN relationship: has_participant CCO:B0058711 ! MS4A5_HUMAN relationship: has_participant CCO:B0058715 ! SAV1_HUMAN relationship: has_participant CCO:B0058724 ! DUS21_HUMAN relationship: has_participant CCO:B0058733 ! Q9H661_HUMAN relationship: has_participant CCO:B0058766 ! LPHN3_HUMAN relationship: has_participant CCO:B0058767 ! ROP1A_HUMAN relationship: has_participant CCO:B0058769 ! GBB4_HUMAN relationship: has_participant CCO:B0058773 ! ILRL2_HUMAN relationship: has_participant CCO:B0058776 ! Q9HB44_HUMAN relationship: has_participant CCO:B0058779 ! PIDD_HUMAN relationship: has_participant CCO:B0058780 ! NMUR1_HUMAN relationship: has_participant CCO:B0058783 ! IL21_HUMAN relationship: has_participant CCO:B0058788 ! Q9HBP3_HUMAN relationship: has_participant CCO:B0058793 ! ELTD1_HUMAN relationship: has_participant CCO:B0058794 ! LGR6_HUMAN relationship: has_participant CCO:B0058812 ! PLXA4_HUMAN relationship: has_participant CCO:B0058816 ! Q9HCP9_HUMAN relationship: has_participant CCO:B0058818 ! PDE11_HUMAN relationship: has_participant CCO:B0058824 ! Q9HD50_HUMAN relationship: has_participant CCO:B0058826 ! MYO10_HUMAN relationship: has_participant CCO:B0058832 ! IRPL2_HUMAN relationship: has_participant CCO:B0058839 ! CABP5_HUMAN relationship: has_participant CCO:B0058845 ! CABP2_HUMAN relationship: has_participant CCO:B0058846 ! LT4R2_HUMAN relationship: has_participant CCO:B0058851 ! FZD3_HUMAN relationship: has_participant CCO:B0058853 ! IL1AP_HUMAN relationship: has_participant CCO:B0058864 ! GPC5C_HUMAN relationship: has_participant CCO:B0058869 ! OR2S1_HUMAN relationship: has_participant CCO:B0058872 ! GPR84_HUMAN relationship: has_participant CCO:B0058877 ! CNGB3_HUMAN relationship: has_participant CCO:B0058888 ! ASAH2_HUMAN relationship: has_participant CCO:B0058891 ! TLR9_HUMAN relationship: has_participant CCO:B0058892 ! TLR8_HUMAN relationship: has_participant CCO:B0058893 ! Q9NRB8_HUMAN relationship: has_participant CCO:B0058902 ! CYTL1_HUMAN relationship: has_participant CCO:B0058904 ! C42S1_HUMAN relationship: has_participant CCO:B0058908 ! KCNH7_HUMAN relationship: has_participant CCO:B0058909 ! GP173_HUMAN relationship: has_participant CCO:B0058910 ! GPR27_HUMAN relationship: has_participant CCO:B0058912 ! FGF21_HUMAN relationship: has_participant CCO:B0058916 ! Q9NSC9_HUMAN relationship: has_participant CCO:B0058918 ! RL3R1_HUMAN relationship: has_participant CCO:B0058927 ! PLCX1_HUMAN relationship: has_participant CCO:B0058939 ! PAG1_HUMAN relationship: has_participant CCO:B0058948 ! RHBL2_HUMAN relationship: has_participant CCO:B0058952 ! CNTLN_HUMAN relationship: has_participant CCO:B0058954 ! M4A12_HUMAN relationship: has_participant CCO:B0058957 ! CLC5A_HUMAN relationship: has_participant CCO:B0058961 ! FA13B_HUMAN relationship: has_participant CCO:B0058964 ! TLR7_HUMAN relationship: has_participant CCO:B0058965 ! GPR83_HUMAN relationship: has_participant CCO:B0058967 ! Q9NYN8_HUMAN relationship: has_participant CCO:B0058968 ! CELR1_HUMAN relationship: has_participant CCO:B0058975 ! T2R16_HUMAN relationship: has_participant CCO:B0058976 ! T2R14_HUMAN relationship: has_participant CCO:B0058977 ! T2R13_HUMAN relationship: has_participant CCO:B0058978 ! T2R10_HUMAN relationship: has_participant CCO:B0058979 ! TA2R9_HUMAN relationship: has_participant CCO:B0058980 ! TA2R8_HUMAN relationship: has_participant CCO:B0058981 ! TA2R7_HUMAN relationship: has_participant CCO:B0058982 ! TA2R4_HUMAN relationship: has_participant CCO:B0058983 ! TA2R3_HUMAN relationship: has_participant CCO:B0058984 ! TA2R1_HUMAN relationship: has_participant CCO:B0058988 ! SIGL8_HUMAN relationship: has_participant CCO:B0058990 ! Q9NZ48_HUMAN relationship: has_participant CCO:B0058993 ! GPC5D_HUMAN relationship: has_participant CCO:B0058996 ! GPC5B_HUMAN relationship: has_participant CCO:B0059005 ! IRPL1_HUMAN relationship: has_participant CCO:B0059007 ! OR6C3_HUMAN relationship: has_participant CCO:B0059008 ! OR6C2_HUMAN relationship: has_participant CCO:B0059010 ! SPN90_HUMAN relationship: has_participant CCO:B0059011 ! PD1L1_HUMAN relationship: has_participant CCO:B0059016 ! CALL5_HUMAN relationship: has_participant CCO:B0059019 ! CABP3_HUMAN relationship: has_participant CCO:B0059027 ! Q9P0G0_HUMAN relationship: has_participant CCO:B0059035 ! CAC1I_HUMAN relationship: has_participant CCO:B0059036 ! GMIP_HUMAN relationship: has_participant CCO:B0059038 ! TAAR3_HUMAN relationship: has_participant CCO:B0059039 ! TAAR2_HUMAN relationship: has_participant CCO:B0059040 ! OR1A1_HUMAN relationship: has_participant CCO:B0059041 ! Q9P1T0_HUMAN relationship: has_participant CCO:B0059044 ! Q9P1V4_HUMAN relationship: has_participant CCO:B0059047 ! CACO1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059051 ! RHG23_HUMAN relationship: has_participant CCO:B0059055 ! C5ARL_HUMAN relationship: has_participant CCO:B0059061 ! GBG13_HUMAN relationship: has_participant CCO:B0059068 ! XCL2_HUMAN relationship: has_participant CCO:B0059072 ! PI4KB_HUMAN relationship: has_participant CCO:B0059073 ! RBPJL_HUMAN relationship: has_participant CCO:B0059075 ! GBG12_HUMAN relationship: has_participant CCO:B0059079 ! TR10D_HUMAN relationship: has_participant CCO:B0059083 ! RNF14_HUMAN relationship: has_participant CCO:B0059099 ! PPR1B_HUMAN relationship: has_participant CCO:B0059102 ! Q9UDD7_HUMAN relationship: has_participant CCO:B0059111 ! Q9UEV7_HUMAN relationship: has_participant CCO:B0059112 ! Q9UEV8_HUMAN relationship: has_participant CCO:B0059118 ! Q9UFY1_HUMAN relationship: has_participant CCO:B0059120 ! O14J1_HUMAN relationship: has_participant CCO:B0059121 ! OR5V1_HUMAN relationship: has_participant CCO:B0059122 ! O12D3_HUMAN relationship: has_participant CCO:B0059123 ! SRGEF_HUMAN relationship: has_participant CCO:B0059129 ! Q9UH66_HUMAN relationship: has_participant CCO:B0059134 ! ACCN3_HUMAN relationship: has_participant CCO:B0059135 ! CNTP2_HUMAN relationship: has_participant CCO:B0059136 ! IL19_HUMAN relationship: has_participant CCO:B0059147 ! BI2L1_HUMAN relationship: has_participant CCO:B0059149 ! Q9UHV4_HUMAN relationship: has_participant CCO:B0059150 ! RPGFL_HUMAN relationship: has_participant CCO:B0059152 ! EMR2_HUMAN relationship: has_participant CCO:B0059167 ! PLXA1_HUMAN relationship: has_participant CCO:B0059168 ! GP160_HUMAN relationship: has_participant CCO:B0059182 ! GBG8_HUMAN relationship: has_participant CCO:B0059192 ! PITC1_HUMAN relationship: has_participant CCO:B0059193 ! BORG2_HUMAN relationship: has_participant CCO:B0059195 ! O52A1_HUMAN relationship: has_participant CCO:B0059197 ! PRDM4_HUMAN relationship: has_participant CCO:B0059198 ! ITBP2_HUMAN relationship: has_participant CCO:B0059199 ! UR2R_HUMAN relationship: has_participant CCO:B0059202 ! TRHDE_HUMAN relationship: has_participant CCO:B0059204 ! ANGL2_HUMAN relationship: has_participant CCO:B0059221 ! RAB23_HUMAN relationship: has_participant CCO:B0059223 ! KCNH3_HUMAN relationship: has_participant CCO:B0059233 ! FZD4_HUMAN relationship: has_participant CCO:B0059237 ! Q9ULW9_HUMAN relationship: has_participant CCO:B0059238 ! APEL_HUMAN relationship: has_participant CCO:B0059239 ! STAP1_HUMAN relationship: has_participant CCO:B0059240 ! Q9UM77_HUMAN relationship: has_participant CCO:B0059245 ! DAPP1_HUMAN relationship: has_participant CCO:B0059248 ! RHG26_HUMAN relationship: has_participant CCO:B0059250 ! EDAR_HUMAN relationship: has_participant CCO:B0059252 ! Q9UNJ2_HUMAN relationship: has_participant CCO:B0059259 ! GPR34_HUMAN relationship: has_participant CCO:B0059265 ! PLCL2_HUMAN relationship: has_participant CCO:B0059273 ! KCNH4_HUMAN relationship: has_participant CCO:B0059274 ! MOK_HUMAN relationship: has_participant CCO:B0059277 ! CTND2_HUMAN relationship: has_participant CCO:B0059278 ! BAIP2_HUMAN relationship: has_participant CCO:B0059282 ! TENN_HUMAN relationship: has_participant CCO:B0059288 ! Q9Y220_HUMAN relationship: has_participant CCO:B0059289 ! PDE10_HUMAN relationship: has_participant CCO:B0059290 ! NOD1_HUMAN relationship: has_participant CCO:B0059292 ! CCL26_HUMAN relationship: has_participant CCO:B0059293 ! PLAP_HUMAN relationship: has_participant CCO:B0059294 ! ANGP4_HUMAN relationship: has_participant CCO:B0059295 ! RASD1_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN relationship: has_participant CCO:B0059314 ! PTN22_HUMAN relationship: has_participant CCO:B0059315 ! AXN2_HUMAN relationship: has_participant CCO:B0059316 ! GPR52_HUMAN relationship: has_participant CCO:B0059317 ! GPR55_HUMAN relationship: has_participant CCO:B0059322 ! AR2BP_HUMAN relationship: has_participant CCO:B0059338 ! 3BP1_HUMAN relationship: has_participant CCO:B0059341 ! OR2W1_HUMAN relationship: has_participant CCO:B0059342 ! SIT1_HUMAN relationship: has_participant CCO:B0059347 ! HBS1L_HUMAN relationship: has_participant CCO:B0059353 ! AAKB1_HUMAN relationship: has_participant CCO:B0059356 ! O10H1_HUMAN relationship: has_participant CCO:B0059359 ! PLXD1_HUMAN relationship: has_participant CCO:B0059362 ! RPGF2_HUMAN relationship: has_participant CCO:B0059363 ! GPSM3_HUMAN relationship: has_participant CCO:B0059364 ! Q9Y4I4_HUMAN relationship: has_participant CCO:B0059369 ! LRP12_HUMAN relationship: has_participant CCO:B0059370 ! RIPK3_HUMAN relationship: has_participant CCO:B0059374 ! OR1A2_HUMAN relationship: has_participant CCO:B0059377 ! ANGL3_HUMAN relationship: has_participant CCO:B0059379 ! HRH3_HUMAN relationship: has_participant CCO:B0059380 ! O51B4_HUMAN relationship: has_participant CCO:B0059381 ! O51B2_HUMAN relationship: has_participant CCO:B0059385 ! MRCKB_HUMAN relationship: has_participant CCO:B0059386 ! NOX1_HUMAN relationship: has_participant CCO:B0059387 ! TNR18_HUMAN relationship: has_participant CCO:B0059389 ! WIF1_HUMAN relationship: has_participant CCO:B0059391 ! NR2E3_HUMAN relationship: has_participant CCO:B0059392 ! NPFF2_HUMAN relationship: has_participant CCO:B0059393 ! GPR44_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN relationship: has_participant CCO:B0059397 ! GPR56_HUMAN relationship: has_participant CCO:B0059408 ! SMA5O_HUMAN relationship: has_participant CCO:B0059413 ! TNR11_HUMAN [Term] id: CCO:P0000709 name: cell surface receptor linked signal transduction namespace: biological_process def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell." [GOC:mah] subset: gosubset_prok xref: GO:0007166 xref: Reactome:110437 is_a: CCO:P0000708 ! signal transduction relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0001477 ! IL2RA_HUMAN relationship: has_participant CCO:B0001479 ! ANXA1_HUMAN relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0001508 ! CD28_HUMAN relationship: has_participant CCO:B0001517 ! IFM1_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0002010 ! MADD_HUMAN relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN relationship: has_participant CCO:B0005438 ! MET_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005611 ! CBL_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005707 ! TNR14_HUMAN relationship: has_participant CCO:B0005713 ! ANM1_HUMAN relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0005819 ! CBLB_HUMAN relationship: has_participant CCO:B0005875 ! CD59_HUMAN relationship: has_participant CCO:B0005902 ! LEPR_HUMAN relationship: has_participant CCO:B0006039 ! SMO_HUMAN relationship: has_participant CCO:B0006237 ! STC2_HUMAN relationship: has_participant CCO:B0015124 ! GIPR_HUMAN relationship: has_participant CCO:B0015966 ! IFNB_HUMAN relationship: has_participant CCO:B0015973 ! IFNA2_HUMAN relationship: has_participant CCO:B0016650 ! FCERB_HUMAN relationship: has_participant CCO:B0016680 ! ANPRA_HUMAN relationship: has_participant CCO:B0016681 ! ANPRB_HUMAN relationship: has_participant CCO:B0018657 ! MERTK_HUMAN relationship: has_participant CCO:B0018660 ! Q15516_HUMAN relationship: has_participant CCO:B0018697 ! EDNRB_HUMAN relationship: has_participant CCO:B0019143 ! ASGR2_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0023521 ! CD2_HUMAN relationship: has_participant CCO:B0025184 ! IL6RB_HUMAN relationship: has_participant CCO:B0031622 ! CDD_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0032298 ! I17RA_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0034147 ! I12R2_HUMAN relationship: has_participant CCO:B0036600 ! NKG2A_HUMAN relationship: has_participant CCO:B0037934 ! IRF9_HUMAN relationship: has_participant CCO:B0038854 ! FZD5_HUMAN relationship: has_participant CCO:B0038855 ! FZD1_HUMAN relationship: has_participant CCO:B0038856 ! FZD7_HUMAN relationship: has_participant CCO:B0038857 ! FZD2_HUMAN relationship: has_participant CCO:B0038861 ! FZD9_HUMAN relationship: has_participant CCO:B0038863 ! FZD8_HUMAN relationship: has_participant CCO:B0038865 ! FZD10_HUMAN relationship: has_participant CCO:B0038932 ! TRPV1_HUMAN relationship: has_participant CCO:B0038965 ! CCL2_HUMAN relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: has_participant CCO:B0042830 ! FCERA_HUMAN relationship: has_participant CCO:B0043443 ! CENA1_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0050788 ! SSR1_HUMAN relationship: has_participant CCO:B0053745 ! A3KMP8_HUMAN relationship: has_participant CCO:B0054041 ! A8MUH3_HUMAN relationship: has_participant CCO:B0054064 ! A8MVP6_HUMAN relationship: has_participant CCO:B0054225 ! B1AK49_HUMAN relationship: has_participant CCO:B0054302 ! SIRB1_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0054417 ! GP182_HUMAN relationship: has_participant CCO:B0054436 ! CCL25_HUMAN relationship: has_participant CCO:B0054498 ! GALR2_HUMAN relationship: has_participant CCO:B0054549 ! FZD6_HUMAN relationship: has_participant CCO:B0054562 ! DOK2_HUMAN relationship: has_participant CCO:B0054592 ! LIRA1_HUMAN relationship: has_participant CCO:B0054593 ! LIRB3_HUMAN relationship: has_participant CCO:B0054594 ! LIRB5_HUMAN relationship: has_participant CCO:B0054675 ! O75889_HUMAN relationship: has_participant CCO:B0054740 ! I18RA_HUMAN relationship: has_participant CCO:B0054771 ! TTRAP_HUMAN relationship: has_participant CCO:B0054780 ! NTR2_HUMAN relationship: has_participant CCO:B0054811 ! BY55_HUMAN relationship: has_participant CCO:B0054812 ! IGSF6_HUMAN relationship: has_participant CCO:B0054830 ! CO5_HUMAN relationship: has_participant CCO:B0054842 ! PRL_HUMAN relationship: has_participant CCO:B0054875 ! CXL10_HUMAN relationship: has_participant CCO:B0054890 ! CD3D_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054916 ! CD3E_HUMAN relationship: has_participant CCO:B0054924 ! ACM4_HUMAN relationship: has_participant CCO:B0054928 ! CD14_HUMAN relationship: has_participant CCO:B0054933 ! IL6RA_HUMAN relationship: has_participant CCO:B0054949 ! CD3G_HUMAN relationship: has_participant CCO:B0054950 ! TACD2_HUMAN relationship: has_participant CCO:B0054974 ! ARRS_HUMAN relationship: has_participant CCO:B0054996 ! CD79A_HUMAN relationship: has_participant CCO:B0055010 ! GP1BB_HUMAN relationship: has_participant CCO:B0055021 ! MIF_HUMAN relationship: has_participant CCO:B0055035 ! CD19_HUMAN relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055053 ! PRLR_HUMAN relationship: has_participant CCO:B0055059 ! ANFB_HUMAN relationship: has_participant CCO:B0055060 ! IL7RA_HUMAN relationship: has_participant CCO:B0055085 ! INAR1_HUMAN relationship: has_participant CCO:B0055103 ! LAG3_HUMAN relationship: has_participant CCO:B0055130 ! CD3Z_HUMAN relationship: has_participant CCO:B0055139 ! DRD4_HUMAN relationship: has_participant CCO:B0055175 ! CXCR1_HUMAN relationship: has_participant CCO:B0055176 ! CXCR2_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN relationship: has_participant CCO:B0055217 ! FCERG_HUMAN relationship: has_participant CCO:B0055218 ! BKRB2_HUMAN relationship: has_participant CCO:B0055224 ! OXYR_HUMAN relationship: has_participant CCO:B0055252 ! GASR_HUMAN relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055296 ! BASI_HUMAN relationship: has_participant CCO:B0055319 ! INGR2_HUMAN relationship: has_participant CCO:B0055327 ! TPOR_HUMAN relationship: has_participant CCO:B0055328 ! CD79B_HUMAN relationship: has_participant CCO:B0055341 ! PACR_HUMAN relationship: has_participant CCO:B0055354 ! I12R1_HUMAN relationship: has_participant CCO:B0055355 ! LIFR_HUMAN relationship: has_participant CCO:B0055394 ! P2RY1_HUMAN relationship: has_participant CCO:B0055406 ! INAR2_HUMAN relationship: has_participant CCO:B0055410 ! KC1A_HUMAN relationship: has_participant CCO:B0055413 ! CD97_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055474 ! CCR5_HUMAN relationship: has_participant CCO:B0055502 ! STC1_HUMAN relationship: has_participant CCO:B0055523 ! GEM_HUMAN relationship: has_participant CCO:B0055538 ! GFRA1_HUMAN relationship: has_participant CCO:B0055607 ! SMS_HUMAN relationship: has_participant CCO:B0055640 ! PI42B_HUMAN relationship: has_participant CCO:B0055652 ! I13R1_HUMAN relationship: has_participant CCO:B0055696 ! CO4A3_HUMAN relationship: has_participant CCO:B0055857 ! KLRB1_HUMAN relationship: has_participant CCO:B0055889 ! KLRD1_HUMAN relationship: has_participant CCO:B0055917 ! BIRC3_HUMAN relationship: has_participant CCO:B0055941 ! Q13731_HUMAN relationship: has_participant CCO:B0056021 ! Q14868_HUMAN relationship: has_participant CCO:B0056043 ! RAGE_HUMAN relationship: has_participant CCO:B0056064 ! Q15452_HUMAN relationship: has_participant CCO:B0056149 ! LY6E_HUMAN relationship: has_participant CCO:B0056833 ! Q6KAV0_HUMAN relationship: has_participant CCO:B0056849 ! Q6N0A5_HUMAN relationship: has_participant CCO:B0056871 ! JMJD6_HUMAN relationship: has_participant CCO:B0056952 ! I27RA_HUMAN relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0057298 ! DTX1_HUMAN relationship: has_participant CCO:B0057459 ! LIRB2_HUMAN relationship: has_participant CCO:B0057560 ! CLC1A_HUMAN relationship: has_participant CCO:B0057595 ! NFAM1_HUMAN relationship: has_participant CCO:B0057937 ! Q8TDT9_HUMAN relationship: has_participant CCO:B0058120 ! IGSF2_HUMAN relationship: has_participant CCO:B0058121 ! TNR25_HUMAN relationship: has_participant CCO:B0058202 ! KLRG1_HUMAN relationship: has_participant CCO:B0058358 ! MAGI1_HUMAN relationship: has_participant CCO:B0058424 ! P2RX7_HUMAN relationship: has_participant CCO:B0058434 ! OSMR_HUMAN relationship: has_participant CCO:B0058443 ! DOK1_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058462 ! BAG1_HUMAN relationship: has_participant CCO:B0058651 ! BRD8_HUMAN relationship: has_participant CCO:B0058685 ! SEM6A_HUMAN relationship: has_participant CCO:B0058786 ! MKNK2_HUMAN relationship: has_participant CCO:B0058851 ! FZD3_HUMAN relationship: has_participant CCO:B0059011 ! PD1L1_HUMAN relationship: has_participant CCO:B0059014 ! KLRF1_HUMAN relationship: has_participant CCO:B0059031 ! IL17C_HUMAN relationship: has_participant CCO:B0059037 ! CLC1B_HUMAN relationship: has_participant CCO:B0059069 ! CLCF1_HUMAN relationship: has_participant CCO:B0059113 ! MARCO_HUMAN relationship: has_participant CCO:B0059146 ! CLC2D_HUMAN relationship: has_participant CCO:B0059153 ! EVL_HUMAN relationship: has_participant CCO:B0059233 ! FZD4_HUMAN relationship: has_participant CCO:B0059234 ! CBLC_HUMAN relationship: has_participant CCO:B0059241 ! CLC4A_HUMAN relationship: has_participant CCO:B0059330 ! SIGL9_HUMAN relationship: has_participant CCO:B0059407 ! CABIN_HUMAN relationship: has_participant CCO:B0059423 ! LY96_HUMAN [Term] id: CCO:P0000710 name: enzyme linked receptor protein signaling pathway namespace: biological_process def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase." [GOC:mah, ISBN:0185316194] synonym: "enzyme linked receptor protein signalling pathway" EXACT [] xref: GO:0007167 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0058814 ! GPVI_HUMAN [Term] id: CCO:P0000711 name: receptor guanylyl cyclase signaling pathway namespace: biological_process def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses guanylyl cyclase activity." [GOC:mah] synonym: "receptor guanylyl cyclase signalling pathway" EXACT [] xref: GO:0007168 is_a: CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: has_participant CCO:B0016682 ! GUC2D_HUMAN relationship: has_participant CCO:B0016684 ! GUC2F_HUMAN relationship: has_participant CCO:B0016685 ! GUC2C_HUMAN relationship: has_participant CCO:B0025070 ! PDZD3_HUMAN relationship: has_participant CCO:B0054537 ! GBG7_HUMAN relationship: has_participant CCO:B0059244 ! GUC1B_HUMAN [Term] id: CCO:P0000712 name: transmembrane receptor protein tyrosine kinase signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand." [GOC:ceb] synonym: "transmembrane receptor protein tyrosine kinase signalling pathway" EXACT [] xref: GO:0007169 is_a: CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: has_participant CCO:B0001390 ! MTSS1_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001532 ! PACA_HUMAN relationship: has_participant CCO:B0001568 ! EPHB2_HUMAN relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005628 ! ALK_HUMAN relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0005719 ! VGFR1_HUMAN relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0005832 ! EPHA2_HUMAN relationship: has_participant CCO:B0005833 ! EPHB4_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0006024 ! EPHB6_HUMAN relationship: has_participant CCO:B0006158 ! DDR1_HUMAN relationship: has_participant CCO:B0014941 ! EPHA6_HUMAN relationship: has_participant CCO:B0014942 ! EPHA4_HUMAN relationship: has_participant CCO:B0014944 ! EPHA5_HUMAN relationship: has_participant CCO:B0014946 ! EPHAA_HUMAN relationship: has_participant CCO:B0014947 ! Q6UWM0_HUMAN relationship: has_participant CCO:B0014952 ! Q6P4R6_HUMAN relationship: has_participant CCO:B0014956 ! Q96L35_HUMAN relationship: has_participant CCO:B0014957 ! EPHA8_HUMAN relationship: has_participant CCO:B0014960 ! Q8N3Z2_HUMAN relationship: has_participant CCO:B0014961 ! EPHA7_HUMAN relationship: has_participant CCO:B0014962 ! A8CDT5_HUMAN relationship: has_participant CCO:B0014963 ! Q8IUX6_HUMAN relationship: has_participant CCO:B0014967 ! EPHA3_HUMAN relationship: has_participant CCO:B0014968 ! EPHB3_HUMAN relationship: has_participant CCO:B0014969 ! EPHB1_HUMAN relationship: has_participant CCO:B0014973 ! EPHA1_HUMAN relationship: has_participant CCO:B0015778 ! PILRB_HUMAN relationship: has_participant CCO:B0018701 ! Q9BUD7_HUMAN relationship: has_participant CCO:B0018717 ! Q9UK79_HUMAN relationship: has_participant CCO:B0019991 ! A2ABL4_HUMAN relationship: has_participant CCO:B0020505 ! PGFRA_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN relationship: has_participant CCO:B0023006 ! PTPRT_HUMAN relationship: has_participant CCO:B0029064 ! Q17RW0_HUMAN relationship: has_participant CCO:B0029069 ! INSRR_HUMAN relationship: has_participant CCO:B0029082 ! ROS_HUMAN relationship: has_participant CCO:B0031949 ! FINC_HUMAN relationship: has_participant CCO:B0038385 ! RPGF1_HUMAN relationship: has_participant CCO:B0041593 ! NCOA4_HUMAN relationship: has_participant CCO:B0048923 ! B1AKC9_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0049552 ! A9YLN5_HUMAN relationship: has_participant CCO:B0049553 ! A9YLN4_HUMAN relationship: has_participant CCO:B0049556 ! Q5H8Y1_HUMAN relationship: has_participant CCO:B0049557 ! A9YLN6_HUMAN relationship: has_participant CCO:B0053813 ! A6NF12_HUMAN relationship: has_participant CCO:B0054098 ! A8MXI6_HUMAN relationship: has_participant CCO:B0054321 ! GFRA2_HUMAN relationship: has_participant CCO:B0054437 ! RPA34_HUMAN relationship: has_participant CCO:B0054562 ! DOK2_HUMAN relationship: has_participant CCO:B0054670 ! O75810_HUMAN relationship: has_participant CCO:B0054748 ! MPZL1_HUMAN relationship: has_participant CCO:B0054824 ! DHE3_HUMAN relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0054856 ! CD8A_HUMAN relationship: has_participant CCO:B0054861 ! CRYAB_HUMAN relationship: has_participant CCO:B0054892 ! NTRK1_HUMAN relationship: has_participant CCO:B0054912 ! CSF1R_HUMAN relationship: has_participant CCO:B0054916 ! CD3E_HUMAN relationship: has_participant CCO:B0054920 ! CO1A2_HUMAN relationship: has_participant CCO:B0054944 ! SPRC_HUMAN relationship: has_participant CCO:B0054946 ! CD7_HUMAN relationship: has_participant CCO:B0054977 ! KIT_HUMAN relationship: has_participant CCO:B0054983 ! CD8B_HUMAN relationship: has_participant CCO:B0055082 ! HMGA1_HUMAN relationship: has_participant CCO:B0055125 ! EDN2_HUMAN relationship: has_participant CCO:B0055158 ! PTPRG_HUMAN relationship: has_participant CCO:B0055199 ! LYOX_HUMAN relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN relationship: has_participant CCO:B0055214 ! LTK_HUMAN relationship: has_participant CCO:B0055218 ! BKRB2_HUMAN relationship: has_participant CCO:B0055297 ! TIMP3_HUMAN relationship: has_participant CCO:B0055304 ! VGFR3_HUMAN relationship: has_participant CCO:B0055305 ! VGFR2_HUMAN relationship: has_participant CCO:B0055341 ! PACR_HUMAN relationship: has_participant CCO:B0055699 ! ROR1_HUMAN relationship: has_participant CCO:B0055715 ! TIE2_HUMAN relationship: has_participant CCO:B0055856 ! PTPRJ_HUMAN relationship: has_participant CCO:B0055872 ! LCP2_HUMAN relationship: has_participant CCO:B0056133 ! NTRK3_HUMAN relationship: has_participant CCO:B0056161 ! NTRK2_HUMAN relationship: has_participant CCO:B0056178 ! DDR2_HUMAN relationship: has_participant CCO:B0056407 ! Q59GJ1_HUMAN relationship: has_participant CCO:B0056641 ! Q5UBV6_HUMAN relationship: has_participant CCO:B0056650 ! Q5VTU6_HUMAN relationship: has_participant CCO:B0056843 ! Q6MZT2_HUMAN relationship: has_participant CCO:B0057270 ! Q86W07_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: has_participant CCO:B0057957 ! DOK4_HUMAN relationship: has_participant CCO:B0058025 ! Q8WXJ7_HUMAN relationship: has_participant CCO:B0058060 ! SHC3_HUMAN relationship: has_participant CCO:B0058131 ! CNKR1_HUMAN relationship: has_participant CCO:B0058436 ! Q99662_HUMAN relationship: has_participant CCO:B0058443 ! DOK1_HUMAN relationship: has_participant CCO:B0058453 ! NRTN_HUMAN relationship: has_participant CCO:B0058465 ! SEM3C_HUMAN [Term] id: CCO:P0000713 name: activation of transmembrane receptor protein tyrosine kinase activity namespace: biological_process def: "Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity." [GOC:dph, GOC:tb] synonym: "transmembrane receptor protein tyrosine kinase activation" RELATED [GOC:dph, GOC:tb] synonym: "transmembrane receptor protein tyrosine kinase dimerization" RELATED [GOC:dph, GOC:mtg_lung] xref: GO:0007171 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0015778 ! PILRB_HUMAN relationship: has_participant CCO:B0032804 ! ACHA3_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0055053 ! PRLR_HUMAN relationship: part_of CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:P0000714 name: signal complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. Complex formation involves dimerization of a receptor protein tyrosine kinase followed by the association of several different intracellular signaling molecules with the cytoplasmic tails of the receptors." [PMID:9646862] synonym: "signal complex formation" EXACT [] xref: GO:0007172 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005812 ! FAK1_HUMAN relationship: has_participant CCO:B0005837 ! PAXI_HUMAN relationship: has_participant CCO:B0005846 ! FAK2_HUMAN relationship: has_participant CCO:B0054133 ! A8MYY5_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0054916 ! CD3E_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0055904 ! JIP2_HUMAN relationship: has_participant CCO:B0056411 ! Q59GM6_HUMAN relationship: has_participant CCO:B0056693 ! Q658W2_HUMAN relationship: has_participant CCO:B0057392 ! Q8IYN9_HUMAN relationship: part_of CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:P0000715 name: epidermal growth factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands." [GOC:ceb] synonym: "EGF receptor signaling pathway" EXACT [] synonym: "EGF receptor signalling pathway" EXACT [] synonym: "EGFR signaling pathway" EXACT [] synonym: "epidermal growth factor receptor signalling pathway" EXACT [] xref: GO:0007173 xref: Reactome:177929 xref: Reactome:211781 xref: Reactome:221546 xref: Reactome:230157 xref: Reactome:238186 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0005424 ! EP15_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005611 ! CBL_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0021671 ! HBEGF_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN relationship: has_participant CCO:B0054653 ! KS6A5_HUMAN relationship: has_participant CCO:B0055415 ! CAMLG_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN relationship: has_participant CCO:B0055985 ! GRB7_HUMAN relationship: has_participant CCO:B0056176 ! DGKD_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0057602 ! REPS2_HUMAN relationship: has_participant CCO:B0058060 ! SHC3_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN [Term] id: CCO:P0000716 name: epidermal growth factor ligand processing namespace: biological_process def: "The proteolysis of epidermal growth factor after its internalization via binding to its receptor." [GOC:isa_complete, PMID:2985587] synonym: "EGF receptor ligand processing" EXACT [] xref: GO:0007174 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000715 ! epidermal growth factor receptor signaling pathway [Term] id: CCO:P0000717 name: negative regulation of epidermal growth factor receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of EGF receptor activity." [GOC:go_curators] synonym: "down regulation of epidermal growth factor receptor activity" EXACT [] synonym: "down-regulation of epidermal growth factor receptor activity" EXACT [] synonym: "downregulation of epidermal growth factor receptor activity" EXACT [] synonym: "EGF receptor downregulation" EXACT [] synonym: "inhibition of epidermal growth factor receptor activity" NARROW [] synonym: "negative regulation of EGF receptor activity" EXACT [] synonym: "negative regulation of EGFR activity" EXACT [] xref: GO:0007175 xref: GO:0007177 is_a: CCO:P0000718 ! regulation of epidermal growth factor receptor activity is_a: CCO:P0002034 ! negative regulation of epidermal growth factor receptor signaling pathway relationship: has_participant CCO:B0026583 ! SNX6_HUMAN relationship: has_participant CCO:B0059234 ! CBLC_HUMAN [Term] id: CCO:P0000718 name: regulation of epidermal growth factor receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of EGF receptor activity." [GOC:dph, GOC:go_curators] synonym: "regulation of EGF receptor activity" EXACT [] synonym: "regulation of EGFR activity" EXACT [] xref: GO:0007176 is_a: CCO:P0002033 ! regulation of epidermal growth factor receptor signaling pathway relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN [Term] id: CCO:P0000719 name: transmembrane receptor protein serine/threonine kinase signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand." [GOC:mah] synonym: "transmembrane receptor protein serine/threonine kinase signalling pathway" EXACT [] xref: GO:0007178 is_a: CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0001767 ! BMPR2_HUMAN relationship: has_participant CCO:B0005437 ! BMR1A_HUMAN relationship: has_participant CCO:B0005542 ! TGFR2_HUMAN relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0020367 ! Q6IR47_HUMAN relationship: has_participant CCO:B0020370 ! TGFR1_HUMAN relationship: has_participant CCO:B0020371 ! BMR1B_HUMAN relationship: has_participant CCO:B0030652 ! Q13161_HUMAN relationship: has_participant CCO:B0054682 ! AKAP3_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0055940 ! AVR2B_HUMAN [Term] id: CCO:P0000720 name: transforming growth factor beta receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands." [GOC:mah] synonym: "TGF-beta receptor signaling pathway" EXACT [] synonym: "TGF-beta receptor signalling pathway" EXACT [] synonym: "TGFbeta receptor signaling pathway" EXACT [] synonym: "TGFbeta receptor signalling pathway" EXACT [] synonym: "transforming growth factor beta receptor signalling pathway" EXACT [] xref: GO:0007179 xref: Reactome:170834 xref: Reactome:211602 xref: Reactome:221377 xref: Reactome:230015 xref: Reactome:238033 xref: Reactome:244845 is_a: CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001523 ! PGDH_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0001791 ! LTBP2_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005437 ! BMR1A_HUMAN relationship: has_participant CCO:B0005531 ! TAB1_HUMAN relationship: has_participant CCO:B0006180 ! GDF9_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0042116 ! GDF5_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0054151 ! A9J6M5_HUMAN relationship: has_participant CCO:B0054308 ! LFTY2_HUMAN relationship: has_participant CCO:B0054376 ! GDF8_HUMAN relationship: has_participant CCO:B0054406 ! SMAD7_HUMAN relationship: has_participant CCO:B0054414 ! SMAD9_HUMAN relationship: has_participant CCO:B0054488 ! SMAD6_HUMAN relationship: has_participant CCO:B0054560 ! O60466_HUMAN relationship: has_participant CCO:B0054655 ! FOXH1_HUMAN relationship: has_participant CCO:B0054657 ! LFTY1_HUMAN relationship: has_participant CCO:B0054758 ! ZFYV9_HUMAN relationship: has_participant CCO:B0054859 ! CO3A1_HUMAN relationship: has_participant CCO:B0055421 ! FNTA_HUMAN relationship: has_participant CCO:B0055528 ! BMP3B_HUMAN relationship: has_participant CCO:B0055875 ! KLF10_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056114 ! SMAD1_HUMAN relationship: has_participant CCO:B0057218 ! Q7Z7L4_HUMAN relationship: has_participant CCO:B0058446 ! SMAD5_HUMAN relationship: has_participant CCO:B0058466 ! GDF15_HUMAN [Term] id: CCO:P0000721 name: transforming growth factor beta receptor complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a type II transforming growth factor beta (TGFbeta) receptor dimer with a type I TGFbeta receptor dimer, following ligand binding, to form a heterotetrameric TGFbeta receptor complex." [GOC:jl, http://en.wikipedia.org/wiki/TGF_beta_signaling_pathway] synonym: "TGF-beta receptor complex assembly" EXACT [] synonym: "TGFbeta receptor complex assembly" EXACT [] xref: GO:0007181 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0020370 ! TGFR1_HUMAN relationship: has_participant CCO:B0054758 ! ZFYV9_HUMAN relationship: has_participant CCO:B0055774 ! FMOD_HUMAN relationship: has_participant CCO:B0057490 ! EID2_HUMAN relationship: part_of CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0000722 name: common-partner SMAD protein phosphorylation namespace: biological_process xref: GO:0007182 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0000723 name: SMAD protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins." [GOC:isa_complete] synonym: "SMAD protein heteromerization" EXACT [] xref: GO:0007183 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0054758 ! ZFYV9_HUMAN relationship: has_participant CCO:B0057490 ! EID2_HUMAN relationship: part_of CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0000724 name: SMAD protein nuclear translocation namespace: biological_process xref: GO:0007184 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0025823 ! TOB1_HUMAN relationship: has_participant CCO:B0054758 ! ZFYV9_HUMAN relationship: part_of CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0000725 name: transmembrane receptor protein tyrosine phosphatase signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine phosphatase binding to its physiological ligand." [GOC:mah] synonym: "transmembrane receptor protein tyrosine phosphatase signalling pathway" EXACT [] xref: GO:0007185 is_a: CCO:P0000710 ! enzyme linked receptor protein signaling pathway relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0023019 ! PTPRU_HUMAN relationship: has_participant CCO:B0054681 ! TRIO_HUMAN relationship: has_participant CCO:B0054975 ! PTPRF_HUMAN relationship: has_participant CCO:B0055157 ! PTPRD_HUMAN relationship: has_participant CCO:B0057975 ! FRS2_HUMAN [Term] id: CCO:P0000726 name: G-protein coupled receptor protein signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand." [GOC:mah] synonym: "G protein coupled receptor protein signaling pathway" EXACT [] synonym: "G protein coupled receptor protein signalling pathway" EXACT [] synonym: "G-protein coupled receptor protein signalling pathway" EXACT [] synonym: "G-protein-coupled receptor protein signaling pathway" EXACT [] synonym: "G-protein-coupled receptor protein signalling pathway" EXACT [] synonym: "GPCR protein signaling pathway" EXACT [] synonym: "GPCR protein signalling pathway" EXACT [] xref: GO:0007186 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001504 ! IL8_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0001610 ! PK3CB_HUMAN relationship: has_participant CCO:B0001690 ! CALM_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0002236 ! GP132_HUMAN relationship: has_participant CCO:B0005326 ! PK3CG_HUMAN relationship: has_participant CCO:B0005374 ! APLP2_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005492 ! GPSM2_HUMAN relationship: has_participant CCO:B0005493 ! GNAI1_HUMAN relationship: has_participant CCO:B0005506 ! FSHR_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005546 ! CELR3_HUMAN relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN relationship: has_participant CCO:B0005723 ! MTR1A_HUMAN relationship: has_participant CCO:B0005724 ! MTR1B_HUMAN relationship: has_participant CCO:B0005754 ! GNAI2_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0006039 ! SMO_HUMAN relationship: has_participant CCO:B0006120 ! ARL3_HUMAN relationship: has_participant CCO:B0006306 ! GP135_HUMAN relationship: has_participant CCO:B0006317 ! GABR1_HUMAN relationship: has_participant CCO:B0015122 ! GLR_HUMAN relationship: has_participant CCO:B0015123 ! GLP1R_HUMAN relationship: has_participant CCO:B0015124 ! GIPR_HUMAN relationship: has_participant CCO:B0015126 ! Q8NHB4_HUMAN relationship: has_participant CCO:B0015129 ! Q6ZN22_HUMAN relationship: has_participant CCO:B0015134 ! GLP2R_HUMAN relationship: has_participant CCO:B0015136 ! SCTR_HUMAN relationship: has_participant CCO:B0016067 ! Q4G0Q6_HUMAN relationship: has_participant CCO:B0016073 ! Q6P5R4_HUMAN relationship: has_participant CCO:B0016650 ! FCERB_HUMAN relationship: has_participant CCO:B0016983 ! Q8NH25_HUMAN relationship: has_participant CCO:B0016986 ! P2RY8_HUMAN relationship: has_participant CCO:B0017123 ! PROK2_HUMAN relationship: has_participant CCO:B0017773 ! T2R40_HUMAN relationship: has_participant CCO:B0018438 ! CCRL1_HUMAN relationship: has_participant CCO:B0018440 ! CCR10_HUMAN relationship: has_participant CCO:B0018485 ! CLTR2_HUMAN relationship: has_participant CCO:B0018486 ! CLTR1_HUMAN relationship: has_participant CCO:B0018692 ! Q5W0G9_HUMAN relationship: has_participant CCO:B0018695 ! EDNRA_HUMAN relationship: has_participant CCO:B0018697 ! EDNRB_HUMAN relationship: has_participant CCO:B0019877 ! Q7KZS6_HUMAN relationship: has_participant CCO:B0020776 ! RGS19_HUMAN relationship: has_participant CCO:B0020777 ! RGS13_HUMAN relationship: has_participant CCO:B0021202 ! A2A3C6_HUMAN relationship: has_participant CCO:B0021203 ! A2A3C1_HUMAN relationship: has_participant CCO:B0021208 ! A2A3C2_HUMAN relationship: has_participant CCO:B0021209 ! A2A3C3_HUMAN relationship: has_participant CCO:B0021210 ! BAI2_HUMAN relationship: has_participant CCO:B0021417 ! CALRL_HUMAN relationship: has_participant CCO:B0021419 ! A4D1G6_HUMAN relationship: has_participant CCO:B0022719 ! Q6IF88_HUMAN relationship: has_participant CCO:B0022721 ! OR5K3_HUMAN relationship: has_participant CCO:B0022723 ! OR5K1_HUMAN relationship: has_participant CCO:B0022725 ! Q8NHB6_HUMAN relationship: has_participant CCO:B0022726 ! O5AC2_HUMAN relationship: has_participant CCO:B0022728 ! OR5H1_HUMAN relationship: has_participant CCO:B0022729 ! O5H15_HUMAN relationship: has_participant CCO:B0022730 ! Q6IF87_HUMAN relationship: has_participant CCO:B0022731 ! OR5K2_HUMAN relationship: has_participant CCO:B0022838 ! Q8NEI9_HUMAN relationship: has_participant CCO:B0022839 ! Q8NHC0_HUMAN relationship: has_participant CCO:B0022840 ! Q8NH98_HUMAN relationship: has_participant CCO:B0022842 ! Q8NH65_HUMAN relationship: has_participant CCO:B0022843 ! Q9UPJ0_HUMAN relationship: has_participant CCO:B0022844 ! Q8WZ85_HUMAN relationship: has_participant CCO:B0022845 ! Q8NHB5_HUMAN relationship: has_participant CCO:B0022846 ! Q8NH97_HUMAN relationship: has_participant CCO:B0022847 ! Q8NH99_HUMAN relationship: has_participant CCO:B0022848 ! Q9P1R1_HUMAN relationship: has_participant CCO:B0022849 ! Q8NH46_HUMAN relationship: has_participant CCO:B0022852 ! Q8NGT4_HUMAN relationship: has_participant CCO:B0022854 ! Q8NHC1_HUMAN relationship: has_participant CCO:B0022856 ! Q8NGP1_HUMAN relationship: has_participant CCO:B0022857 ! Q8NHB9_HUMAN relationship: has_participant CCO:B0022858 ! Q8NH45_HUMAN relationship: has_participant CCO:B0022861 ! O7E24_HUMAN relationship: has_participant CCO:B0022862 ! Q9UDD8_HUMAN relationship: has_participant CCO:B0022863 ! Q15618_HUMAN relationship: has_participant CCO:B0022865 ! Q8NHA1_HUMAN relationship: has_participant CCO:B0022866 ! Q8NG89_HUMAN relationship: has_participant CCO:B0022870 ! Q96N54_HUMAN relationship: has_participant CCO:B0022873 ! Q8NGD7_HUMAN relationship: has_participant CCO:B0024303 ! Q4VBB4_HUMAN relationship: has_participant CCO:B0024306 ! PSYR_HUMAN relationship: has_participant CCO:B0024308 ! GPR4_HUMAN relationship: has_participant CCO:B0026166 ! LANC1_HUMAN relationship: has_participant CCO:B0026726 ! MRGRF_HUMAN relationship: has_participant CCO:B0027200 ! FPR1_HUMAN relationship: has_participant CCO:B0027548 ! Q5JWE9_HUMAN relationship: has_participant CCO:B0027550 ! GNAS2_HUMAN relationship: has_participant CCO:B0027551 ! GNAL_HUMAN relationship: has_participant CCO:B0027553 ! Q5FWY2_HUMAN relationship: has_participant CCO:B0027554 ! GNAS1_HUMAN relationship: has_participant CCO:B0027555 ! O60726_HUMAN relationship: has_participant CCO:B0027556 ! A6NI00_HUMAN relationship: has_participant CCO:B0027557 ! Q5JW64_HUMAN relationship: has_participant CCO:B0027558 ! Q14455_HUMAN relationship: has_participant CCO:B0027559 ! Q5JWD1_HUMAN relationship: has_participant CCO:B0027560 ! O75632_HUMAN relationship: has_participant CCO:B0027561 ! O75633_HUMAN relationship: has_participant CCO:B0027562 ! Q86XU3_HUMAN relationship: has_participant CCO:B0027564 ! Q5JWE8_HUMAN relationship: has_participant CCO:B0027571 ! SLIT2_HUMAN relationship: has_participant CCO:B0027573 ! Q5T0V3_HUMAN relationship: has_participant CCO:B0027574 ! Q5T0V2_HUMAN relationship: has_participant CCO:B0028201 ! OR1D2_HUMAN relationship: has_participant CCO:B0028205 ! Q6IFM2_HUMAN relationship: has_participant CCO:B0028206 ! Q6IFL7_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN relationship: has_participant CCO:B0029013 ! OR9I1_HUMAN relationship: has_participant CCO:B0029014 ! Q6IF62_HUMAN relationship: has_participant CCO:B0029015 ! OR5W2_HUMAN relationship: has_participant CCO:B0029017 ! OR5B3_HUMAN relationship: has_participant CCO:B0029019 ! Q8NH91_HUMAN relationship: has_participant CCO:B0029022 ! OR8K5_HUMAN relationship: has_participant CCO:B0029023 ! OR5L1_HUMAN relationship: has_participant CCO:B0029024 ! OR5B2_HUMAN relationship: has_participant CCO:B0029025 ! OR8U1_HUMAN relationship: has_participant CCO:B0029027 ! A8MUX1_HUMAN relationship: has_participant CCO:B0029028 ! OR5BC_HUMAN relationship: has_participant CCO:B0029029 ! OR5R1_HUMAN relationship: has_participant CCO:B0029030 ! OR5C1_HUMAN relationship: has_participant CCO:B0029031 ! OR8G5_HUMAN relationship: has_participant CCO:B0029032 ! Q6IEU2_HUMAN relationship: has_participant CCO:B0029033 ! OR5J2_HUMAN relationship: has_participant CCO:B0029034 ! OR8D4_HUMAN relationship: has_participant CCO:B0029035 ! O5AR1_HUMAN relationship: has_participant CCO:B0029036 ! Q6IFM9_HUMAN relationship: has_participant CCO:B0029037 ! A8MXK6_HUMAN relationship: has_participant CCO:B0029038 ! O5AS1_HUMAN relationship: has_participant CCO:B0029039 ! OR5BH_HUMAN relationship: has_participant CCO:B0029040 ! OR5L2_HUMAN relationship: has_participant CCO:B0030075 ! A8MTR7_HUMAN relationship: has_participant CCO:B0030243 ! Q6NT27_HUMAN relationship: has_participant CCO:B0030246 ! Q6LCB5_HUMAN relationship: has_participant CCO:B0030249 ! GNAZ_HUMAN relationship: has_participant CCO:B0030251 ! GNA11_HUMAN relationship: has_participant CCO:B0030261 ! GNA14_HUMAN relationship: has_participant CCO:B0030262 ! GNAT2_HUMAN relationship: has_participant CCO:B0030265 ! Q6B6N3_HUMAN relationship: has_participant CCO:B0030266 ! GNAT1_HUMAN relationship: has_participant CCO:B0030269 ! GNAI3_HUMAN relationship: has_participant CCO:B0030552 ! MC3R_HUMAN relationship: has_participant CCO:B0030561 ! MSHR_HUMAN relationship: has_participant CCO:B0030569 ! MC5R_HUMAN relationship: has_participant CCO:B0030574 ! MC4R_HUMAN relationship: has_participant CCO:B0030577 ! ACTHR_HUMAN relationship: has_participant CCO:B0031607 ! TA2R5_HUMAN relationship: has_participant CCO:B0032345 ! Q5Y190_HUMAN relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0033252 ! OPSX_HUMAN relationship: has_participant CCO:B0033253 ! A6NEB4_HUMAN relationship: has_participant CCO:B0033254 ! OPN4_HUMAN relationship: has_participant CCO:B0033335 ! Q6IFC7_HUMAN relationship: has_participant CCO:B0033337 ! A8MTX1_HUMAN relationship: has_participant CCO:B0033338 ! OR5T1_HUMAN relationship: has_participant CCO:B0033339 ! A8MW53_HUMAN relationship: has_participant CCO:B0033340 ! O5AK3_HUMAN relationship: has_participant CCO:B0033341 ! OR5K4_HUMAN relationship: has_participant CCO:B0033342 ! A8MWJ9_HUMAN relationship: has_participant CCO:B0033343 ! Q6IFC8_HUMAN relationship: has_participant CCO:B0033344 ! OR9Q2_HUMAN relationship: has_participant CCO:B0033345 ! A8MXY9_HUMAN relationship: has_participant CCO:B0033346 ! OR5I1_HUMAN relationship: has_participant CCO:B0033347 ! O5AC1_HUMAN relationship: has_participant CCO:B0033348 ! A8MVK2_HUMAN relationship: has_participant CCO:B0033349 ! O5H14_HUMAN relationship: has_participant CCO:B0033351 ! Q8IXE7_HUMAN relationship: has_participant CCO:B0033405 ! GP126_HUMAN relationship: has_participant CCO:B0033412 ! GP112_HUMAN relationship: has_participant CCO:B0033418 ! GPR64_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0036109 ! CO3_HUMAN relationship: has_participant CCO:B0037018 ! PREX2_HUMAN relationship: has_participant CCO:B0037083 ! RXFP2_HUMAN relationship: has_participant CCO:B0037085 ! RXFP1_HUMAN relationship: has_participant CCO:B0037087 ! Q3KU23_HUMAN relationship: has_participant CCO:B0037223 ! A8MSY3_HUMAN relationship: has_participant CCO:B0037226 ! O00325_HUMAN relationship: has_participant CCO:B0037228 ! Q5CZ60_HUMAN relationship: has_participant CCO:B0037229 ! PE2R3_HUMAN relationship: has_participant CCO:B0037230 ! Q5CZ59_HUMAN relationship: has_participant CCO:B0037231 ! Q5CZ62_HUMAN relationship: has_participant CCO:B0037235 ! A8K3L9_HUMAN relationship: has_participant CCO:B0037236 ! Q147X8_HUMAN relationship: has_participant CCO:B0038258 ! ADA1A_HUMAN relationship: has_participant CCO:B0038260 ! 5HT2C_HUMAN relationship: has_participant CCO:B0038261 ! Q7Z5R9_HUMAN relationship: has_participant CCO:B0038262 ! HRH2_HUMAN relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN relationship: has_participant CCO:B0038265 ! ADA1D_HUMAN relationship: has_participant CCO:B0038266 ! 5HT1D_HUMAN relationship: has_participant CCO:B0038267 ! ADA2B_HUMAN relationship: has_participant CCO:B0038590 ! Q6IFJ9_HUMAN relationship: has_participant CCO:B0038591 ! Q8NG79_HUMAN relationship: has_participant CCO:B0038592 ! OR6M1_HUMAN relationship: has_participant CCO:B0038594 ! A6NJJ1_HUMAN relationship: has_participant CCO:B0038854 ! FZD5_HUMAN relationship: has_participant CCO:B0038855 ! FZD1_HUMAN relationship: has_participant CCO:B0038856 ! FZD7_HUMAN relationship: has_participant CCO:B0038857 ! FZD2_HUMAN relationship: has_participant CCO:B0038861 ! FZD9_HUMAN relationship: has_participant CCO:B0038863 ! FZD8_HUMAN relationship: has_participant CCO:B0038865 ! FZD10_HUMAN relationship: has_participant CCO:B0038965 ! CCL2_HUMAN relationship: has_participant CCO:B0041668 ! GROA_HUMAN relationship: has_participant CCO:B0041921 ! B0UXY8_HUMAN relationship: has_participant CCO:B0041922 ! GABR2_HUMAN relationship: has_participant CCO:B0041924 ! Q8NHA5_HUMAN relationship: has_participant CCO:B0041925 ! B0UXY7_HUMAN relationship: has_participant CCO:B0041927 ! A6NNW8_HUMAN relationship: has_participant CCO:B0042221 ! A8MT20_HUMAN relationship: has_participant CCO:B0042222 ! GRM3_HUMAN relationship: has_participant CCO:B0042225 ! GRM4_HUMAN relationship: has_participant CCO:B0042226 ! Q8N0Z0_HUMAN relationship: has_participant CCO:B0042227 ! GRM7_HUMAN relationship: has_participant CCO:B0042228 ! A4D0Y3_HUMAN relationship: has_participant CCO:B0042229 ! Q8NHA9_HUMAN relationship: has_participant CCO:B0042230 ! GRM5_HUMAN relationship: has_participant CCO:B0042232 ! Q59GK5_HUMAN relationship: has_participant CCO:B0042233 ! Q99997_HUMAN relationship: has_participant CCO:B0042237 ! Q86YG3_HUMAN relationship: has_participant CCO:B0042238 ! Q6J164_HUMAN relationship: has_participant CCO:B0042239 ! GRM2_HUMAN relationship: has_participant CCO:B0042241 ! GRM8_HUMAN relationship: has_participant CCO:B0042244 ! GRM6_HUMAN relationship: has_participant CCO:B0042245 ! GRM1_HUMAN relationship: has_participant CCO:B0042246 ! A8K1R9_HUMAN relationship: has_participant CCO:B0042247 ! Q2PNZ6_HUMAN relationship: has_participant CCO:B0042251 ! Q6ZMQ2_HUMAN relationship: has_participant CCO:B0042255 ! Q59HC2_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN relationship: has_participant CCO:B0043867 ! LPAR4_HUMAN relationship: has_participant CCO:B0049157 ! PAR4_HUMAN relationship: has_participant CCO:B0049159 ! Q7Z3W3_HUMAN relationship: has_participant CCO:B0049161 ! PAR2_HUMAN relationship: has_participant CCO:B0049379 ! GNAT3_HUMAN relationship: has_participant CCO:B0049381 ! GNAO_HUMAN relationship: has_participant CCO:B0049445 ! A6NEW7_HUMAN relationship: has_participant CCO:B0049448 ! Q53TQ2_HUMAN relationship: has_participant CCO:B0049452 ! NK2R_HUMAN relationship: has_participant CCO:B0049455 ! NK3R_HUMAN relationship: has_participant CCO:B0049457 ! NK1R_HUMAN relationship: has_participant CCO:B0049806 ! OR8H1_HUMAN relationship: has_participant CCO:B0049809 ! A8MYY4_HUMAN relationship: has_participant CCO:B0049812 ! A8MYM5_HUMAN relationship: has_participant CCO:B0049813 ! OR8B4_HUMAN relationship: has_participant CCO:B0049814 ! OR8H3_HUMAN relationship: has_participant CCO:B0049816 ! OR8H2_HUMAN relationship: has_participant CCO:B0049817 ! OR5MB_HUMAN relationship: has_participant CCO:B0050753 ! OPRD_HUMAN relationship: has_participant CCO:B0050755 ! SSR2_HUMAN relationship: has_participant CCO:B0050756 ! Q9H573_HUMAN relationship: has_participant CCO:B0050758 ! OPRK_HUMAN relationship: has_participant CCO:B0050760 ! A6NL10_HUMAN relationship: has_participant CCO:B0050761 ! Q8IXB0_HUMAN relationship: has_participant CCO:B0050764 ! NPBW2_HUMAN relationship: has_participant CCO:B0050772 ! Q8IWW3_HUMAN relationship: has_participant CCO:B0050781 ! OPRX_HUMAN relationship: has_participant CCO:B0050782 ! NPBW1_HUMAN relationship: has_participant CCO:B0050784 ! Q8IWP3_HUMAN relationship: has_participant CCO:B0050785 ! SSR5_HUMAN relationship: has_participant CCO:B0050788 ! SSR1_HUMAN relationship: has_participant CCO:B0050791 ! Q5TBX0_HUMAN relationship: has_participant CCO:B0050792 ! Q8IWW4_HUMAN relationship: has_participant CCO:B0050793 ! SSR4_HUMAN relationship: has_participant CCO:B0050794 ! SSR3_HUMAN relationship: has_participant CCO:B0051877 ! OR8D2_HUMAN relationship: has_participant CCO:B0051880 ! OR8G1_HUMAN relationship: has_participant CCO:B0051882 ! OR8G2_HUMAN relationship: has_participant CCO:B0051883 ! OR8U9_HUMAN relationship: has_participant CCO:B0051887 ! O5AK2_HUMAN relationship: has_participant CCO:B0051892 ! OR8U8_HUMAN relationship: has_participant CCO:B0051893 ! O5AP2_HUMAN relationship: has_participant CCO:B0053696 ! A0A502_HUMAN relationship: has_participant CCO:B0053703 ! A0PJU7_HUMAN relationship: has_participant CCO:B0053711 ! A1L156_HUMAN relationship: has_participant CCO:B0053724 ! A2BDZ0_HUMAN relationship: has_participant CCO:B0053725 ! A2BDZ2_HUMAN relationship: has_participant CCO:B0053726 ! A2BEC2_HUMAN relationship: has_participant CCO:B0053727 ! A2BF33_HUMAN relationship: has_participant CCO:B0053728 ! A2BF34_HUMAN relationship: has_participant CCO:B0053742 ! OR2M5_HUMAN relationship: has_participant CCO:B0053754 ! A4D225_HUMAN relationship: has_participant CCO:B0053758 ! A4D2G2_HUMAN relationship: has_participant CCO:B0053759 ! O2A25_HUMAN relationship: has_participant CCO:B0053771 ! A4QMS5_HUMAN relationship: has_participant CCO:B0053782 ! A6NC00_HUMAN relationship: has_participant CCO:B0053783 ! A6NC31_HUMAN relationship: has_participant CCO:B0053786 ! O6C74_HUMAN relationship: has_participant CCO:B0053788 ! O14I1_HUMAN relationship: has_participant CCO:B0053793 ! O6C68_HUMAN relationship: has_participant CCO:B0053797 ! A6NDW2_HUMAN relationship: has_participant CCO:B0053800 ! A6NE11_HUMAN relationship: has_participant CCO:B0053805 ! A6NE96_HUMAN relationship: has_participant CCO:B0053807 ! A6NEF2_HUMAN relationship: has_participant CCO:B0053816 ! OR6C6_HUMAN relationship: has_participant CCO:B0053817 ! OR2W5_HUMAN relationship: has_participant CCO:B0053818 ! A6NFD6_HUMAN relationship: has_participant CCO:B0053824 ! A6NFR0_HUMAN relationship: has_participant CCO:B0053834 ! A6NGT9_HUMAN relationship: has_participant CCO:B0053835 ! O51F1_HUMAN relationship: has_participant CCO:B0053836 ! OR2T8_HUMAN relationship: has_participant CCO:B0053839 ! A6NH54_HUMAN relationship: has_participant CCO:B0053842 ! A6NH69_HUMAN relationship: has_participant CCO:B0053845 ! O4C46_HUMAN relationship: has_participant CCO:B0053849 ! A6NHK6_HUMAN relationship: has_participant CCO:B0053861 ! A6NIH4_HUMAN relationship: has_participant CCO:B0053862 ! O6C70_HUMAN relationship: has_participant CCO:B0053863 ! A6NIQ0_HUMAN relationship: has_participant CCO:B0053866 ! A6NJ05_HUMAN relationship: has_participant CCO:B0053872 ! A6NJJ3_HUMAN relationship: has_participant CCO:B0053875 ! O6C65_HUMAN relationship: has_participant CCO:B0053886 ! A6NKK7_HUMAN relationship: has_participant CCO:B0053887 ! A6NKM1_HUMAN relationship: has_participant CCO:B0053890 ! O6C75_HUMAN relationship: has_participant CCO:B0053892 ! OR5BL_HUMAN relationship: has_participant CCO:B0053893 ! A6NL96_HUMAN relationship: has_participant CCO:B0053902 ! O2AG2_HUMAN relationship: has_participant CCO:B0053904 ! O6C76_HUMAN relationship: has_participant CCO:B0053908 ! O52A4_HUMAN relationship: has_participant CCO:B0053909 ! A6NMV7_HUMAN relationship: has_participant CCO:B0053910 ! O4C45_HUMAN relationship: has_participant CCO:B0053911 ! A6NN09_HUMAN relationship: has_participant CCO:B0053914 ! O2AT4_HUMAN relationship: has_participant CCO:B0053917 ! A6NNL3_HUMAN relationship: has_participant CCO:B0053921 ! A6NNY4_HUMAN relationship: has_participant CCO:B0053957 ! A8K2J1_HUMAN relationship: has_participant CCO:B0053959 ! A8K2Y6_HUMAN relationship: has_participant CCO:B0053960 ! A8K305_HUMAN relationship: has_participant CCO:B0053962 ! A8K3C0_HUMAN relationship: has_participant CCO:B0053966 ! A8K4E4_HUMAN relationship: has_participant CCO:B0054018 ! A8MSZ9_HUMAN relationship: has_participant CCO:B0054022 ! A8MT74_HUMAN relationship: has_participant CCO:B0054024 ! A8MTE1_HUMAN relationship: has_participant CCO:B0054037 ! A8MU07_HUMAN relationship: has_participant CCO:B0054039 ! A8MUF8_HUMAN relationship: has_participant CCO:B0054042 ! A8MUM9_HUMAN relationship: has_participant CCO:B0054045 ! A8MUS4_HUMAN relationship: has_participant CCO:B0054049 ! A8MUW4_HUMAN relationship: has_participant CCO:B0054050 ! A8MUY8_HUMAN relationship: has_participant CCO:B0054052 ! A8MV06_HUMAN relationship: has_participant CCO:B0054058 ! A8MVF0_HUMAN relationship: has_participant CCO:B0054061 ! A8MVM5_HUMAN relationship: has_participant CCO:B0054066 ! A8MVV5_HUMAN relationship: has_participant CCO:B0054073 ! A8MW54_HUMAN relationship: has_participant CCO:B0054079 ! A8MWG5_HUMAN relationship: has_participant CCO:B0054080 ! A8MWI1_HUMAN relationship: has_participant CCO:B0054086 ! A8MX01_HUMAN relationship: has_participant CCO:B0054093 ! A8MX88_HUMAN relationship: has_participant CCO:B0054094 ! A8MXA6_HUMAN relationship: has_participant CCO:B0054095 ! A8MXE9_HUMAN relationship: has_participant CCO:B0054097 ! A8MXI2_HUMAN relationship: has_participant CCO:B0054100 ! A8MXL5_HUMAN relationship: has_participant CCO:B0054104 ! A8MXU4_HUMAN relationship: has_participant CCO:B0054108 ! A8MXZ2_HUMAN relationship: has_participant CCO:B0054109 ! A8MXZ4_HUMAN relationship: has_participant CCO:B0054111 ! A8MY27_HUMAN relationship: has_participant CCO:B0054116 ! A8MY83_HUMAN relationship: has_participant CCO:B0054135 ! A8MZ16_HUMAN relationship: has_participant CCO:B0054142 ! A8MZG7_HUMAN relationship: has_participant CCO:B0054144 ! A8MZL3_HUMAN relationship: has_participant CCO:B0054186 ! B0UY34_HUMAN relationship: has_participant CCO:B0054189 ! B0V1T2_HUMAN relationship: has_participant CCO:B0054190 ! B0V1T3_HUMAN relationship: has_participant CCO:B0054192 ! B0V386_HUMAN relationship: has_participant CCO:B0054198 ! B0ZBD2_HUMAN relationship: has_participant CCO:B0054199 ! B0ZBD3_HUMAN relationship: has_participant CCO:B0054200 ! B0ZBD8_HUMAN relationship: has_participant CCO:B0054224 ! B1AK19_HUMAN relationship: has_participant CCO:B0054241 ! B1ALU1_HUMAN relationship: has_participant CCO:B0054242 ! B1ALU2_HUMAN relationship: has_participant CCO:B0054243 ! B1ALU3_HUMAN relationship: has_participant CCO:B0054244 ! B1ALU4_HUMAN relationship: has_participant CCO:B0054245 ! B1ALU5_HUMAN relationship: has_participant CCO:B0054246 ! B1ALU6_HUMAN relationship: has_participant CCO:B0054249 ! B1AM21_HUMAN relationship: has_participant CCO:B0054256 ! B1AMW4_HUMAN relationship: has_participant CCO:B0054259 ! B1AN12_HUMAN relationship: has_participant CCO:B0054268 ! B1AP63_HUMAN relationship: has_participant CCO:B0054282 ! B1B0A5_HUMAN relationship: has_participant CCO:B0054283 ! B1B1F0_HUMAN relationship: has_participant CCO:B0054291 ! GPR25_HUMAN relationship: has_participant CCO:B0054306 ! GPR31_HUMAN relationship: has_participant CCO:B0054316 ! P2Y10_HUMAN relationship: has_participant CCO:B0054318 ! CCRL2_HUMAN relationship: has_participant CCO:B0054333 ! CXCR6_HUMAN relationship: has_participant CCO:B0054335 ! CCBP2_HUMAN relationship: has_participant CCO:B0054348 ! BAI1_HUMAN relationship: has_participant CCO:B0054353 ! OR7AH_HUMAN relationship: has_participant CCO:B0054356 ! GBGT2_HUMAN relationship: has_participant CCO:B0054360 ! GP171_HUMAN relationship: has_participant CCO:B0054368 ! O14694_HUMAN relationship: has_participant CCO:B0054378 ! TAAR5_HUMAN relationship: has_participant CCO:B0054382 ! FFAR1_HUMAN relationship: has_participant CCO:B0054383 ! FFAR3_HUMAN relationship: has_participant CCO:B0054391 ! GIPC1_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN relationship: has_participant CCO:B0054417 ! GP182_HUMAN relationship: has_participant CCO:B0054421 ! DEFB2_HUMAN relationship: has_participant CCO:B0054432 ! GPR37_HUMAN relationship: has_participant CCO:B0054436 ! CCL25_HUMAN relationship: has_participant CCO:B0054444 ! GPR42_HUMAN relationship: has_participant CCO:B0054448 ! FFAR2_HUMAN relationship: has_participant CCO:B0054458 ! O43192_HUMAN relationship: has_participant CCO:B0054459 ! MTLR_HUMAN relationship: has_participant CCO:B0054460 ! GPR39_HUMAN relationship: has_participant CCO:B0054498 ! GALR2_HUMAN relationship: has_participant CCO:B0054502 ! OX1R_HUMAN relationship: has_participant CCO:B0054503 ! OX2R_HUMAN relationship: has_participant CCO:B0054505 ! O43627_HUMAN relationship: has_participant CCO:B0054518 ! OR1F1_HUMAN relationship: has_participant CCO:B0054528 ! OR2T1_HUMAN relationship: has_participant CCO:B0054529 ! O43898_HUMAN relationship: has_participant CCO:B0054536 ! BAI3_HUMAN relationship: has_participant CCO:B0054537 ! GBG7_HUMAN relationship: has_participant CCO:B0054549 ! FZD6_HUMAN relationship: has_participant CCO:B0054552 ! O10H2_HUMAN relationship: has_participant CCO:B0054553 ! O10H3_HUMAN relationship: has_participant CCO:B0054554 ! O60411_HUMAN relationship: has_participant CCO:B0054555 ! OR7C2_HUMAN relationship: has_participant CCO:B0054558 ! OR1I1_HUMAN relationship: has_participant CCO:B0054576 ! GALR3_HUMAN relationship: has_participant CCO:B0054585 ! ETBR2_HUMAN relationship: has_participant CCO:B0054629 ! TULP3_HUMAN relationship: has_participant CCO:B0054630 ! GPR32_HUMAN relationship: has_participant CCO:B0054640 ! LGR5_HUMAN relationship: has_participant CCO:B0054678 ! RGS9_HUMAN relationship: has_participant CCO:B0054684 ! OR2B3_HUMAN relationship: has_participant CCO:B0054685 ! OR2J3_HUMAN relationship: has_participant CCO:B0054686 ! OR2J2_HUMAN relationship: has_participant CCO:B0054694 ! OR7C1_HUMAN relationship: has_participant CCO:B0054695 ! OR7AA_HUMAN relationship: has_participant CCO:B0054700 ! RGS11_HUMAN relationship: has_participant CCO:B0054710 ! LPHN1_HUMAN relationship: has_participant CCO:B0054715 ! OR2F2_HUMAN relationship: has_participant CCO:B0054716 ! O4F21_HUMAN relationship: has_participant CCO:B0054717 ! OR2A4_HUMAN relationship: has_participant CCO:B0054718 ! KCNK2_HUMAN relationship: has_participant CCO:B0054727 ! S1PR2_HUMAN relationship: has_participant CCO:B0054736 ! OR5F1_HUMAN relationship: has_participant CCO:B0054737 ! OR6A2_HUMAN relationship: has_participant CCO:B0054752 ! OR2C1_HUMAN relationship: has_participant CCO:B0054767 ! LPHN2_HUMAN relationship: has_participant CCO:B0054769 ! O95499_HUMAN relationship: has_participant CCO:B0054780 ! NTR2_HUMAN relationship: has_participant CCO:B0054794 ! GPR75_HUMAN relationship: has_participant CCO:B0054804 ! OR2H2_HUMAN relationship: has_participant CCO:B0054813 ! S1PR4_HUMAN relationship: has_participant CCO:B0054830 ! CO5_HUMAN relationship: has_participant CCO:B0054838 ! TSHB_HUMAN relationship: has_participant CCO:B0054847 ! PTHY_HUMAN relationship: has_participant CCO:B0054848 ! GLUC_HUMAN relationship: has_participant CCO:B0054849 ! VIP_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0054864 ! APOC3_HUMAN relationship: has_participant CCO:B0054879 ! OPSB_HUMAN relationship: has_participant CCO:B0054880 ! OPSR_HUMAN relationship: has_participant CCO:B0054881 ! OPSG_HUMAN relationship: has_participant CCO:B0054888 ! MAS_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054916 ! CD3E_HUMAN relationship: has_participant CCO:B0054919 ! OPSD_HUMAN relationship: has_participant CCO:B0054923 ! ACM2_HUMAN relationship: has_participant CCO:B0054924 ! ACM4_HUMAN relationship: has_participant CCO:B0054929 ! ADRB1_HUMAN relationship: has_participant CCO:B0054934 ! 5HT1A_HUMAN relationship: has_participant CCO:B0054936 ! ACM5_HUMAN relationship: has_participant CCO:B0054937 ! ADA2A_HUMAN relationship: has_participant CCO:B0054955 ! OR4A8_HUMAN relationship: has_participant CCO:B0054956 ! O5AL1_HUMAN relationship: has_participant CCO:B0054957 ! OR4Q2_HUMAN relationship: has_participant CCO:B0054958 ! OR5G3_HUMAN relationship: has_participant CCO:B0054959 ! O10J4_HUMAN relationship: has_participant CCO:B0054960 ! OR4E1_HUMAN relationship: has_participant CCO:B0054961 ! O52Z1_HUMAN relationship: has_participant CCO:B0054964 ! OR9G9_HUMAN relationship: has_participant CCO:B0054969 ! PYY_HUMAN relationship: has_participant CCO:B0054972 ! CCL3_HUMAN relationship: has_participant CCO:B0054986 ! ACM1_HUMAN relationship: has_participant CCO:B0055007 ! MOTI_HUMAN relationship: has_participant CCO:B0055020 ! ADRB3_HUMAN relationship: has_participant CCO:B0055024 ! DRD2_HUMAN relationship: has_participant CCO:B0055054 ! TSHR_HUMAN relationship: has_participant CCO:B0055056 ! GBB3_HUMAN relationship: has_participant CCO:B0055104 ! ADA2C_HUMAN relationship: has_participant CCO:B0055115 ! ACM3_HUMAN relationship: has_participant CCO:B0055129 ! PHOS_HUMAN relationship: has_participant CCO:B0055133 ! CNR1_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055137 ! C5AR_HUMAN relationship: has_participant CCO:B0055138 ! TA2R_HUMAN relationship: has_participant CCO:B0055139 ! DRD4_HUMAN relationship: has_participant CCO:B0055140 ! DRD5_HUMAN relationship: has_participant CCO:B0055152 ! LSHR_HUMAN relationship: has_participant CCO:B0055175 ! CXCR1_HUMAN relationship: has_participant CCO:B0055176 ! CXCR2_HUMAN relationship: has_participant CCO:B0055178 ! FPR3_HUMAN relationship: has_participant CCO:B0055179 ! FPR2_HUMAN relationship: has_participant CCO:B0055180 ! ARBK1_HUMAN relationship: has_participant CCO:B0055181 ! PTAFR_HUMAN relationship: has_participant CCO:B0055182 ! CXCR7_HUMAN relationship: has_participant CCO:B0055187 ! NPY1R_HUMAN relationship: has_participant CCO:B0055197 ! 5HT1B_HUMAN relationship: has_participant CCO:B0055198 ! 5HT2A_HUMAN relationship: has_participant CCO:B0055201 ! NMBR_HUMAN relationship: has_participant CCO:B0055205 ! 5HT1E_HUMAN relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN relationship: has_participant CCO:B0055211 ! AA2BR_HUMAN relationship: has_participant CCO:B0055218 ! BKRB2_HUMAN relationship: has_participant CCO:B0055219 ! V2R_HUMAN relationship: has_participant CCO:B0055221 ! AA1R_HUMAN relationship: has_participant CCO:B0055222 ! GRPR_HUMAN relationship: has_participant CCO:B0055223 ! AGTR1_HUMAN relationship: has_participant CCO:B0055224 ! OXYR_HUMAN relationship: has_participant CCO:B0055225 ! GNA15_HUMAN relationship: has_participant CCO:B0055226 ! 5HT1F_HUMAN relationship: has_participant CCO:B0055227 ! OR1E1_HUMAN relationship: has_participant CCO:B0055228 ! O10J1_HUMAN relationship: has_participant CCO:B0055229 ! GNRHR_HUMAN relationship: has_participant CCO:B0055230 ! CALCR_HUMAN relationship: has_participant CCO:B0055231 ! NTR1_HUMAN relationship: has_participant CCO:B0055251 ! CCKAR_HUMAN relationship: has_participant CCO:B0055252 ! GASR_HUMAN relationship: has_participant CCO:B0055253 ! VIPR1_HUMAN relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055257 ! BRS3_HUMAN relationship: has_participant CCO:B0055258 ! CCR7_HUMAN relationship: has_participant CCO:B0055260 ! CXCR5_HUMAN relationship: has_participant CCO:B0055269 ! AA3R_HUMAN relationship: has_participant CCO:B0055272 ! 5HT7R_HUMAN relationship: has_participant CCO:B0055273 ! CNR2_HUMAN relationship: has_participant CCO:B0055274 ! TRFR_HUMAN relationship: has_participant CCO:B0055275 ! PE2R1_HUMAN relationship: has_participant CCO:B0055276 ! CRFR1_HUMAN relationship: has_participant CCO:B0055287 ! HRH1_HUMAN relationship: has_participant CCO:B0055288 ! PE2R4_HUMAN relationship: has_participant CCO:B0055289 ! MAS1L_HUMAN relationship: has_participant CCO:B0055290 ! APJ_HUMAN relationship: has_participant CCO:B0055293 ! DRD3_HUMAN relationship: has_participant CCO:B0055318 ! V1AR_HUMAN relationship: has_participant CCO:B0055335 ! CASR_HUMAN relationship: has_participant CCO:B0055338 ! P2RY2_HUMAN relationship: has_participant CCO:B0055341 ! PACR_HUMAN relationship: has_participant CCO:B0055342 ! VIPR2_HUMAN relationship: has_participant CCO:B0055343 ! 5HT2B_HUMAN relationship: has_participant CCO:B0055344 ! CCR2_HUMAN relationship: has_participant CCO:B0055358 ! PF2R_HUMAN relationship: has_participant CCO:B0055359 ! PE2R2_HUMAN relationship: has_participant CCO:B0055360 ! PI2R_HUMAN relationship: has_participant CCO:B0055367 ! P2RY5_HUMAN relationship: has_participant CCO:B0055372 ! GPR3_HUMAN relationship: has_participant CCO:B0055373 ! GPR1_HUMAN relationship: has_participant CCO:B0055374 ! XCR1_HUMAN relationship: has_participant CCO:B0055375 ! GPR6_HUMAN relationship: has_participant CCO:B0055378 ! BKRB1_HUMAN relationship: has_participant CCO:B0055382 ! GALR1_HUMAN relationship: has_participant CCO:B0055385 ! GPR12_HUMAN relationship: has_participant CCO:B0055386 ! RGR_HUMAN relationship: has_participant CCO:B0055388 ! OR3A1_HUMAN relationship: has_participant CCO:B0055389 ! OR3A4_HUMAN relationship: has_participant CCO:B0055390 ! OR1G1_HUMAN relationship: has_participant CCO:B0055391 ! OR3A2_HUMAN relationship: has_participant CCO:B0055393 ! 5HT5A_HUMAN relationship: has_participant CCO:B0055394 ! P2RY1_HUMAN relationship: has_participant CCO:B0055395 ! V1BR_HUMAN relationship: has_participant CCO:B0055399 ! SDF1_HUMAN relationship: has_participant CCO:B0055409 ! NMU_HUMAN relationship: has_participant CCO:B0055413 ! CD97_HUMAN relationship: has_participant CCO:B0055414 ! G109B_HUMAN relationship: has_participant CCO:B0055418 ! NPY2R_HUMAN relationship: has_participant CCO:B0055419 ! PTH2R_HUMAN relationship: has_participant CCO:B0055420 ! CX3C1_HUMAN relationship: has_participant CCO:B0055428 ! CXCR3_HUMAN relationship: has_participant CCO:B0055429 ! PRLHR_HUMAN relationship: has_participant CCO:B0055430 ! GPR15_HUMAN relationship: has_participant CCO:B0055433 ! RGS6_HUMAN relationship: has_participant CCO:B0055438 ! RGS7_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055443 ! GBG4_HUMAN relationship: has_participant CCO:B0055444 ! GBG10_HUMAN relationship: has_participant CCO:B0055447 ! NPY4R_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN relationship: has_participant CCO:B0055469 ! P2RY4_HUMAN relationship: has_participant CCO:B0055472 ! CCR3_HUMAN relationship: has_participant CCO:B0055473 ! CCR4_HUMAN relationship: has_participant CCO:B0055474 ! CCR5_HUMAN relationship: has_participant CCO:B0055475 ! CCR6_HUMAN relationship: has_participant CCO:B0055476 ! CCR8_HUMAN relationship: has_participant CCO:B0055477 ! CCR9_HUMAN relationship: has_participant CCO:B0055527 ! UCN1_HUMAN relationship: has_participant CCO:B0055537 ! CCL23_HUMAN relationship: has_participant CCO:B0055565 ! OR2B6_HUMAN relationship: has_participant CCO:B0055566 ! OR4D2_HUMAN relationship: has_participant CCO:B0055567 ! O10A3_HUMAN relationship: has_participant CCO:B0055568 ! O12D2_HUMAN relationship: has_participant CCO:B0055576 ! T2R12_HUMAN relationship: has_participant CCO:B0055577 ! T2R38_HUMAN relationship: has_participant CCO:B0055578 ! T2R39_HUMAN relationship: has_participant CCO:B0055579 ! T2R41_HUMAN relationship: has_participant CCO:B0055580 ! T2R43_HUMAN relationship: has_participant CCO:B0055581 ! T2R44_HUMAN relationship: has_participant CCO:B0055582 ! T2R45_HUMAN relationship: has_participant CCO:B0055583 ! T2R46_HUMAN relationship: has_participant CCO:B0055584 ! T2R47_HUMAN relationship: has_participant CCO:B0055585 ! T2R48_HUMAN relationship: has_participant CCO:B0055586 ! T2R49_HUMAN relationship: has_participant CCO:B0055587 ! T2R50_HUMAN relationship: has_participant CCO:B0055588 ! T2R60_HUMAN relationship: has_participant CCO:B0055589 ! GBG2_HUMAN relationship: has_participant CCO:B0055592 ! OR2B8_HUMAN relationship: has_participant CCO:B0055595 ! DEFB1_HUMAN relationship: has_participant CCO:B0055599 ! GPR85_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN relationship: has_participant CCO:B0055607 ! SMS_HUMAN relationship: has_participant CCO:B0055614 ! GBG11_HUMAN relationship: has_participant CCO:B0055623 ! GBB2_HUMAN relationship: has_participant CCO:B0055631 ! GBG1_HUMAN relationship: has_participant CCO:B0055632 ! GBG3_HUMAN relationship: has_participant CCO:B0055633 ! GBG5_HUMAN relationship: has_participant CCO:B0055713 ! GHRHR_HUMAN relationship: has_participant CCO:B0055718 ! AKA12_HUMAN relationship: has_participant CCO:B0055721 ! GNA12_HUMAN relationship: has_participant CCO:B0055724 ! PTHR1_HUMAN relationship: has_participant CCO:B0055747 ! Q05AH0_HUMAN relationship: has_participant CCO:B0055756 ! Q05C50_HUMAN relationship: has_participant CCO:B0055783 ! CXCL9_HUMAN relationship: has_participant CCO:B0055819 ! Q0VAB0_HUMAN relationship: has_participant CCO:B0055867 ! Q13027_HUMAN relationship: has_participant CCO:B0055890 ! PD2R_HUMAN relationship: has_participant CCO:B0055895 ! GPR17_HUMAN relationship: has_participant CCO:B0055898 ! CRFR2_HUMAN relationship: has_participant CCO:B0055934 ! OR2F1_HUMAN relationship: has_participant CCO:B0055937 ! 5HT4R_HUMAN relationship: has_participant CCO:B0055945 ! ENPP2_HUMAN relationship: has_participant CCO:B0055975 ! EMR1_HUMAN relationship: has_participant CCO:B0055979 ! GPR18_HUMAN relationship: has_participant CCO:B0055981 ! Q14396_HUMAN relationship: has_participant CCO:B0055983 ! GP176_HUMAN relationship: has_participant CCO:B0056029 ! Q14968_HUMAN relationship: has_participant CCO:B0056042 ! P2RY6_HUMAN relationship: has_participant CCO:B0056060 ! P2Y14_HUMAN relationship: has_participant CCO:B0056078 ! OR1Q1_HUMAN relationship: has_participant CCO:B0056079 ! OR4D1_HUMAN relationship: has_participant CCO:B0056080 ! OR1C1_HUMAN relationship: has_participant CCO:B0056081 ! OR8B8_HUMAN relationship: has_participant CCO:B0056082 ! OR7A5_HUMAN relationship: has_participant CCO:B0056100 ! LT4R1_HUMAN relationship: has_participant CCO:B0056104 ! GPR19_HUMAN relationship: has_participant CCO:B0056105 ! NPY5R_HUMAN relationship: has_participant CCO:B0056139 ! Q16503_HUMAN relationship: has_participant CCO:B0056146 ! GP162_HUMAN relationship: has_participant CCO:B0056152 ! CART_HUMAN relationship: has_participant CCO:B0056153 ! DUFFY_HUMAN relationship: has_participant CCO:B0056154 ! C3AR_HUMAN relationship: has_participant CCO:B0056181 ! Q17R53_HUMAN relationship: has_participant CCO:B0056182 ! Q17R96_HUMAN relationship: has_participant CCO:B0056189 ! Q17S10_HUMAN relationship: has_participant CCO:B0056211 ! Q2M3M4_HUMAN relationship: has_participant CCO:B0056216 ! Q2MZ38_HUMAN relationship: has_participant CCO:B0056219 ! Q2NL85_HUMAN relationship: has_participant CCO:B0056241 ! OR4FL_HUMAN relationship: has_participant CCO:B0056248 ! YK037_HUMAN relationship: has_participant CCO:B0056266 ! Q3SAH2_HUMAN relationship: has_participant CCO:B0056280 ! Q3ZAR0_HUMAN relationship: has_participant CCO:B0056294 ! Q495I2_HUMAN relationship: has_participant CCO:B0056308 ! GPR33_HUMAN relationship: has_participant CCO:B0056323 ! Q4TT72_HUMAN relationship: has_participant CCO:B0056328 ! Q4VAM2_HUMAN relationship: has_participant CCO:B0056330 ! Q4VBL7_HUMAN relationship: has_participant CCO:B0056337 ! Q4ZFZ2_HUMAN relationship: has_participant CCO:B0056342 ! Q50KZ9_HUMAN relationship: has_participant CCO:B0056345 ! Q52R92_HUMAN relationship: has_participant CCO:B0056346 ! Q52R94_HUMAN relationship: has_participant CCO:B0056355 ! Q53F99_HUMAN relationship: has_participant CCO:B0056374 ! Q57Z87_HUMAN relationship: has_participant CCO:B0056397 ! Q59G72_HUMAN relationship: has_participant CCO:B0056446 ! Q5IFH6_HUMAN relationship: has_participant CCO:B0056459 ! OR2BB_HUMAN relationship: has_participant CCO:B0056470 ! O10J3_HUMAN relationship: has_participant CCO:B0056479 ! Q5JSM8_HUMAN relationship: has_participant CCO:B0056488 ! Q5JUH9_HUMAN relationship: has_participant CCO:B0056505 ! Q5JY94_HUMAN relationship: has_participant CCO:B0056516 ! Q5KU14_HUMAN relationship: has_participant CCO:B0056519 ! Q5KU21_HUMAN relationship: has_participant CCO:B0056524 ! GP120_HUMAN relationship: has_participant CCO:B0056537 ! Q5ST39_HUMAN relationship: has_participant CCO:B0056539 ! Q5SUJ6_HUMAN relationship: has_participant CCO:B0056540 ! Q5SUJ7_HUMAN relationship: has_participant CCO:B0056541 ! Q5SUK1_HUMAN relationship: has_participant CCO:B0056542 ! Q5SUN7_HUMAN relationship: has_participant CCO:B0056543 ! Q5SUN9_HUMAN relationship: has_participant CCO:B0056568 ! Q5T3H4_HUMAN relationship: has_participant CCO:B0056569 ! Q5T3H5_HUMAN relationship: has_participant CCO:B0056585 ! Q5T5Y4_HUMAN relationship: has_participant CCO:B0056586 ! GP110_HUMAN relationship: has_participant CCO:B0056592 ! GPC6A_HUMAN relationship: has_participant CCO:B0056596 ! GP158_HUMAN relationship: has_participant CCO:B0056624 ! Q5TGK2_HUMAN relationship: has_participant CCO:B0056637 ! OR2G6_HUMAN relationship: has_participant CCO:B0056640 ! GP157_HUMAN relationship: has_participant CCO:B0056644 ! Q5VT13_HUMAN relationship: has_participant CCO:B0056645 ! Q5VT14_HUMAN relationship: has_participant CCO:B0056665 ! Q5VX04_HUMAN relationship: has_participant CCO:B0056691 ! Q63ZY2_HUMAN relationship: has_participant CCO:B0056730 ! GP139_HUMAN relationship: has_participant CCO:B0056734 ! Q6GMT1_HUMAN relationship: has_participant CCO:B0056752 ! Q6I939_HUMAN relationship: has_participant CCO:B0056753 ! Q6I940_HUMAN relationship: has_participant CCO:B0056754 ! Q6I941_HUMAN relationship: has_participant CCO:B0056760 ! OR5MA_HUMAN relationship: has_participant CCO:B0056761 ! Q6IEV0_HUMAN relationship: has_participant CCO:B0056762 ! Q6IEV1_HUMAN relationship: has_participant CCO:B0056763 ! Q6IEV3_HUMAN relationship: has_participant CCO:B0056764 ! OR4CB_HUMAN relationship: has_participant CCO:B0056765 ! Q6IEW7_HUMAN relationship: has_participant CCO:B0056766 ! Q6IEX0_HUMAN relationship: has_participant CCO:B0056767 ! Q6IEX5_HUMAN relationship: has_participant CCO:B0056768 ! OR4F3_HUMAN relationship: has_participant CCO:B0056769 ! Q6IEZ1_HUMAN relationship: has_participant CCO:B0056770 ! Q6IEZ4_HUMAN relationship: has_participant CCO:B0056771 ! OR2T5_HUMAN relationship: has_participant CCO:B0056772 ! OR2T2_HUMAN relationship: has_participant CCO:B0056773 ! Q6IF09_HUMAN relationship: has_participant CCO:B0056774 ! Q6IF12_HUMAN relationship: has_participant CCO:B0056775 ! Q6IF17_HUMAN relationship: has_participant CCO:B0056776 ! Q6IF36_HUMAN relationship: has_participant CCO:B0056777 ! Q6IF40_HUMAN relationship: has_participant CCO:B0056778 ! OR2A2_HUMAN relationship: has_participant CCO:B0056779 ! Q6IF52_HUMAN relationship: has_participant CCO:B0056780 ! O52W1_HUMAN relationship: has_participant CCO:B0056781 ! Q6IF70_HUMAN relationship: has_participant CCO:B0056782 ! Q6IF79_HUMAN relationship: has_participant CCO:B0056783 ! O4A47_HUMAN relationship: has_participant CCO:B0056784 ! O10K2_HUMAN relationship: has_participant CCO:B0056785 ! Q6IFB0_HUMAN relationship: has_participant CCO:B0056786 ! Q6IFD1_HUMAN relationship: has_participant CCO:B0056787 ! Q6IFD3_HUMAN relationship: has_participant CCO:B0056788 ! Q6IFD6_HUMAN relationship: has_participant CCO:B0056789 ! O52E8_HUMAN relationship: has_participant CCO:B0056790 ! Q6IFG3_HUMAN relationship: has_participant CCO:B0056791 ! Q6IFG5_HUMAN relationship: has_participant CCO:B0056792 ! Q6IFG6_HUMAN relationship: has_participant CCO:B0056793 ! Q6IFG8_HUMAN relationship: has_participant CCO:B0056794 ! OR6B2_HUMAN relationship: has_participant CCO:B0056795 ! Q6IFH9_HUMAN relationship: has_participant CCO:B0056796 ! Q6IFI0_HUMAN relationship: has_participant CCO:B0056797 ! Q6IFI1_HUMAN relationship: has_participant CCO:B0056798 ! Q6IFI5_HUMAN relationship: has_participant CCO:B0056799 ! Q6IFI7_HUMAN relationship: has_participant CCO:B0056800 ! Q6IFI8_HUMAN relationship: has_participant CCO:B0056801 ! Q6IFJ4_HUMAN relationship: has_participant CCO:B0056802 ! Q6IFJ8_HUMAN relationship: has_participant CCO:B0056803 ! Q6IFK7_HUMAN relationship: has_participant CCO:B0056804 ! Q6IFK8_HUMAN relationship: has_participant CCO:B0056805 ! Q6IFK9_HUMAN relationship: has_participant CCO:B0056806 ! Q6IFL0_HUMAN relationship: has_participant CCO:B0056807 ! Q6IFL1_HUMAN relationship: has_participant CCO:B0056808 ! Q6IFL9_HUMAN relationship: has_participant CCO:B0056809 ! Q6IFM6_HUMAN relationship: has_participant CCO:B0056810 ! Q6IFM8_HUMAN relationship: has_participant CCO:B0056811 ! Q6IFN2_HUMAN relationship: has_participant CCO:B0056812 ! Q6IFN7_HUMAN relationship: has_participant CCO:B0056813 ! Q6IFP3_HUMAN relationship: has_participant CCO:B0056814 ! Q6IFP9_HUMAN relationship: has_participant CCO:B0056815 ! Q6IFR1_HUMAN relationship: has_participant CCO:B0056816 ! Q6IFR4_HUMAN relationship: has_participant CCO:B0056817 ! Q6IFR5_HUMAN relationship: has_participant CCO:B0056818 ! Q6IFS1_HUMAN relationship: has_participant CCO:B0056839 ! Q6LEE7_HUMAN relationship: has_participant CCO:B0056849 ! Q6N0A5_HUMAN relationship: has_participant CCO:B0056859 ! Q6NTB5_HUMAN relationship: has_participant CCO:B0056860 ! Q6NUP5_HUMAN relationship: has_participant CCO:B0056862 ! GP153_HUMAN relationship: has_participant CCO:B0056864 ! Q6NWR3_HUMAN relationship: has_participant CCO:B0056886 ! Q6P2M6_HUMAN relationship: has_participant CCO:B0056890 ! Q6P5W7_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056923 ! Q6PK25_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0056934 ! GP133_HUMAN relationship: has_participant CCO:B0056936 ! Q6RKA3_HUMAN relationship: has_participant CCO:B0056937 ! Q6RYQ6_HUMAN relationship: has_participant CCO:B0056939 ! Q6S992_HUMAN relationship: has_participant CCO:B0056946 ! OPN5_HUMAN relationship: has_participant CCO:B0056954 ! Q6UXT6_HUMAN relationship: has_participant CCO:B0056968 ! NPSR1_HUMAN relationship: has_participant CCO:B0056984 ! Q6ZMN0_HUMAN relationship: has_participant CCO:B0056989 ! Q6ZMP9_HUMAN relationship: has_participant CCO:B0057034 ! Q6ZQV4_HUMAN relationship: has_participant CCO:B0057089 ! Q6ZW62_HUMAN relationship: has_participant CCO:B0057094 ! Q711G2_HUMAN relationship: has_participant CCO:B0057095 ! Q712M9_HUMAN relationship: has_participant CCO:B0057099 ! Q71U75_HUMAN relationship: has_participant CCO:B0057100 ! Q71V81_HUMAN relationship: has_participant CCO:B0057106 ! Q76L88_HUMAN relationship: has_participant CCO:B0057112 ! YA043_HUMAN relationship: has_participant CCO:B0057125 ! T2R42_HUMAN relationship: has_participant CCO:B0057126 ! BHLH8_HUMAN relationship: has_participant CCO:B0057139 ! TS1R3_HUMAN relationship: has_participant CCO:B0057140 ! TS1R1_HUMAN relationship: has_participant CCO:B0057154 ! OR2W3_HUMAN relationship: has_participant CCO:B0057174 ! Q7Z581_HUMAN relationship: has_participant CCO:B0057181 ! VN1R5_HUMAN relationship: has_participant CCO:B0057182 ! VN1R4_HUMAN relationship: has_participant CCO:B0057188 ! GP142_HUMAN relationship: has_participant CCO:B0057189 ! GP141_HUMAN relationship: has_participant CCO:B0057220 ! GP144_HUMAN relationship: has_participant CCO:B0057221 ! Q86SE3_HUMAN relationship: has_participant CCO:B0057223 ! Q86SF1_HUMAN relationship: has_participant CCO:B0057224 ! Q86SF3_HUMAN relationship: has_participant CCO:B0057225 ! Q86SG0_HUMAN relationship: has_participant CCO:B0057226 ! Q86SG9_HUMAN relationship: has_participant CCO:B0057227 ! Q86SI5_HUMAN relationship: has_participant CCO:B0057229 ! MRGRG_HUMAN relationship: has_participant CCO:B0057230 ! Q86SP4_HUMAN relationship: has_participant CCO:B0057231 ! GP149_HUMAN relationship: has_participant CCO:B0057232 ! EMR4_HUMAN relationship: has_participant CCO:B0057233 ! GP123_HUMAN relationship: has_participant CCO:B0057300 ! GPR97_HUMAN relationship: has_participant CCO:B0057338 ! Q8IV68_HUMAN relationship: has_participant CCO:B0057340 ! WASF4_HUMAN relationship: has_participant CCO:B0057361 ! GP125_HUMAN relationship: has_participant CCO:B0057370 ! Q8IXD9_HUMAN relationship: has_participant CCO:B0057371 ! Q8IXE0_HUMAN relationship: has_participant CCO:B0057372 ! OR4N5_HUMAN relationship: has_participant CCO:B0057374 ! Q8IXE5_HUMAN relationship: has_participant CCO:B0057399 ! Q8IZB1_HUMAN relationship: has_participant CCO:B0057402 ! 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G109A_HUMAN relationship: has_participant CCO:B0057933 ! OXER1_HUMAN relationship: has_participant CCO:B0057934 ! MRGRD_HUMAN relationship: has_participant CCO:B0057935 ! GP152_HUMAN relationship: has_participant CCO:B0057937 ! Q8TDT9_HUMAN relationship: has_participant CCO:B0057938 ! VNRL4_HUMAN relationship: has_participant CCO:B0057939 ! GPBAR_HUMAN relationship: has_participant CCO:B0057940 ! RL3R2_HUMAN relationship: has_participant CCO:B0057941 ! GP151_HUMAN relationship: has_participant CCO:B0057942 ! Q8TDV1_HUMAN relationship: has_participant CCO:B0057943 ! GP148_HUMAN relationship: has_participant CCO:B0057944 ! GP119_HUMAN relationship: has_participant CCO:B0057950 ! TS1R2_HUMAN relationship: has_participant CCO:B0057970 ! Q8WTR3_HUMAN relationship: has_participant CCO:B0057975 ! FRS2_HUMAN relationship: has_participant CCO:B0058018 ! GPR98_HUMAN relationship: has_participant CCO:B0058031 ! Q8WXL5_HUMAN relationship: has_participant CCO:B0058032 ! Q8WXL8_HUMAN relationship: has_participant CCO:B0058033 ! Q8WXN2_HUMAN relationship: has_participant CCO:B0058034 ! Q8WXV1_HUMAN relationship: has_participant CCO:B0058035 ! Q8WXV2_HUMAN relationship: has_participant CCO:B0058036 ! Q8WXZ9_HUMAN relationship: has_participant CCO:B0058052 ! OR8D1_HUMAN relationship: has_participant CCO:B0058053 ! OR5P2_HUMAN relationship: has_participant CCO:B0058054 ! OR5P3_HUMAN relationship: has_participant CCO:B0058055 ! RPGF4_HUMAN relationship: has_participant CCO:B0058056 ! OR1E3_HUMAN relationship: has_participant CCO:B0058067 ! CCL17_HUMAN relationship: has_participant CCO:B0058076 ! LPAR1_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN relationship: has_participant CCO:B0058119 ! Q93003_HUMAN relationship: has_participant CCO:B0058129 ! KISSR_HUMAN relationship: has_participant CCO:B0058135 ! TAAR8_HUMAN relationship: has_participant CCO:B0058141 ! MCHR2_HUMAN relationship: has_participant CCO:B0058168 ! Q96BN9_HUMAN relationship: has_participant CCO:B0058182 ! GP146_HUMAN relationship: has_participant CCO:B0058213 ! P2Y11_HUMAN relationship: has_participant CCO:B0058255 ! GP128_HUMAN relationship: has_participant CCO:B0058259 ! O10C1_HUMAN relationship: has_participant CCO:B0058268 ! MRGX4_HUMAN relationship: has_participant CCO:B0058269 ! MRGX3_HUMAN relationship: has_participant CCO:B0058270 ! MRGX2_HUMAN relationship: has_participant CCO:B0058271 ! MRGX1_HUMAN relationship: has_participant CCO:B0058320 ! QRFPR_HUMAN relationship: has_participant CCO:B0058321 ! GP101_HUMAN relationship: has_participant CCO:B0058322 ! GPR82_HUMAN relationship: has_participant CCO:B0058323 ! OXGR1_HUMAN relationship: has_participant CCO:B0058324 ! GPR78_HUMAN relationship: has_participant CCO:B0058326 ! GNRR2_HUMAN relationship: has_participant CCO:B0058329 ! GP124_HUMAN relationship: has_participant CCO:B0058359 ! OR2M4_HUMAN relationship: has_participant CCO:B0058360 ! OR2M2_HUMAN relationship: has_participant CCO:B0058361 ! OR2V2_HUMAN relationship: has_participant CCO:B0058362 ! OR2A7_HUMAN relationship: has_participant CCO:B0058363 ! O2A14_HUMAN relationship: has_participant CCO:B0058364 ! OR2A5_HUMAN relationship: has_participant CCO:B0058365 ! O14A2_HUMAN relationship: has_participant CCO:B0058366 ! OR4CC_HUMAN relationship: has_participant CCO:B0058367 ! OR4F4_HUMAN relationship: has_participant CCO:B0058368 ! OR4K3_HUMAN relationship: has_participant CCO:B0058369 ! OR1F2_HUMAN relationship: has_participant CCO:B0058370 ! OR7D2_HUMAN relationship: has_participant CCO:B0058371 ! OR8B2_HUMAN relationship: has_participant CCO:B0058372 ! OR6C1_HUMAN relationship: has_participant CCO:B0058373 ! O52E6_HUMAN relationship: has_participant CCO:B0058377 ! TAAR6_HUMAN relationship: has_participant CCO:B0058378 ! TAAR9_HUMAN relationship: has_participant CCO:B0058379 ! TAAR1_HUMAN relationship: has_participant CCO:B0058406 ! Q99061_HUMAN relationship: has_participant CCO:B0058413 ! NPY6R_HUMAN relationship: has_participant CCO:B0058418 ! S1PR3_HUMAN relationship: has_participant CCO:B0058421 ! SORT_HUMAN relationship: has_participant CCO:B0058422 ! GPER_HUMAN relationship: has_participant CCO:B0058433 ! Q99642_HUMAN relationship: has_participant CCO:B0058438 ! GPR20_HUMAN relationship: has_participant CCO:B0058439 ! GPR21_HUMAN relationship: has_participant CCO:B0058440 ! GPR22_HUMAN relationship: has_participant CCO:B0058444 ! MCHR1_HUMAN relationship: has_participant CCO:B0058454 ! CML1_HUMAN relationship: has_participant CCO:B0058469 ! P2Y13_HUMAN relationship: has_participant CCO:B0058545 ! Q9BX81_HUMAN relationship: has_participant CCO:B0058548 ! LGR4_HUMAN relationship: has_participant CCO:B0058549 ! GPR81_HUMAN relationship: has_participant CCO:B0058550 ! GP174_HUMAN relationship: has_participant CCO:B0058551 ! VN1R3_HUMAN relationship: has_participant CCO:B0058565 ! EMR3_HUMAN relationship: has_participant CCO:B0058567 ! GPR87_HUMAN relationship: has_participant CCO:B0058574 ! GNB1L_HUMAN relationship: has_participant CCO:B0058591 ! Q9BZ77_HUMAN relationship: has_participant CCO:B0058594 ! Q9BZC5_HUMAN relationship: has_participant CCO:B0058600 ! GPR63_HUMAN relationship: has_participant CCO:B0058601 ! GPR62_HUMAN relationship: has_participant CCO:B0058602 ! GPR61_HUMAN relationship: has_participant CCO:B0058624 ! OR2B2_HUMAN relationship: has_participant CCO:B0058625 ! OR2H1_HUMAN relationship: has_participant CCO:B0058626 ! OR2J1_HUMAN relationship: has_participant CCO:B0058627 ! O11A1_HUMAN relationship: has_participant CCO:B0058629 ! GPR88_HUMAN relationship: has_participant CCO:B0058630 ! VN1R1_HUMAN relationship: has_participant CCO:B0058632 ! NMUR2_HUMAN relationship: has_participant CCO:B0058633 ! NPFF1_HUMAN relationship: has_participant CCO:B0058663 ! LPAR5_HUMAN relationship: has_participant CCO:B0058667 ! OPN3_HUMAN relationship: has_participant CCO:B0058668 ! O2AG1_HUMAN relationship: has_participant CCO:B0058669 ! O10A5_HUMAN relationship: has_participant CCO:B0058670 ! O10A2_HUMAN relationship: has_participant CCO:B0058671 ! O10A4_HUMAN relationship: has_participant CCO:B0058672 ! OR2D2_HUMAN relationship: has_participant CCO:B0058673 ! S1PR5_HUMAN relationship: has_participant CCO:B0058675 ! P2Y12_HUMAN relationship: has_participant CCO:B0058678 ! O51E2_HUMAN relationship: has_participant CCO:B0058681 ! O52A5_HUMAN relationship: has_participant CCO:B0058682 ! Q9H2C6_HUMAN relationship: has_participant CCO:B0058683 ! O51V1_HUMAN relationship: has_participant CCO:B0058694 ! O51B5_HUMAN relationship: has_participant CCO:B0058695 ! O51B6_HUMAN relationship: has_participant CCO:B0058696 ! O51M1_HUMAN relationship: has_participant CCO:B0058697 ! O51J1_HUMAN relationship: has_participant CCO:B0058698 ! O51I1_HUMAN relationship: has_participant CCO:B0058699 ! O51I2_HUMAN relationship: has_participant CCO:B0058700 ! Q9H345_HUMAN relationship: has_participant CCO:B0058701 ! O52D1_HUMAN relationship: has_participant CCO:B0058706 ! HRH4_HUMAN relationship: has_participant CCO:B0058743 ! Q9H7Q2_HUMAN relationship: has_participant CCO:B0058766 ! LPHN3_HUMAN relationship: has_participant CCO:B0058775 ! Q9HB42_HUMAN relationship: has_participant CCO:B0058776 ! Q9HB44_HUMAN relationship: has_participant CCO:B0058780 ! NMUR1_HUMAN relationship: has_participant CCO:B0058793 ! ELTD1_HUMAN relationship: has_participant CCO:B0058794 ! LGR6_HUMAN relationship: has_participant CCO:B0058824 ! Q9HD50_HUMAN relationship: has_participant CCO:B0058846 ! LT4R2_HUMAN relationship: has_participant CCO:B0058851 ! FZD3_HUMAN relationship: has_participant CCO:B0058864 ! GPC5C_HUMAN relationship: has_participant CCO:B0058869 ! OR2S1_HUMAN relationship: has_participant CCO:B0058872 ! GPR84_HUMAN relationship: has_participant CCO:B0058893 ! Q9NRB8_HUMAN relationship: has_participant CCO:B0058909 ! GP173_HUMAN relationship: has_participant CCO:B0058910 ! GPR27_HUMAN relationship: has_participant CCO:B0058916 ! Q9NSC9_HUMAN relationship: has_participant CCO:B0058918 ! RL3R1_HUMAN relationship: has_participant CCO:B0058965 ! GPR83_HUMAN relationship: has_participant CCO:B0058967 ! Q9NYN8_HUMAN relationship: has_participant CCO:B0058968 ! CELR1_HUMAN relationship: has_participant CCO:B0058975 ! T2R16_HUMAN relationship: has_participant CCO:B0058976 ! T2R14_HUMAN relationship: has_participant CCO:B0058977 ! T2R13_HUMAN relationship: has_participant CCO:B0058978 ! T2R10_HUMAN relationship: has_participant CCO:B0058979 ! TA2R9_HUMAN relationship: has_participant CCO:B0058980 ! TA2R8_HUMAN relationship: has_participant CCO:B0058981 ! TA2R7_HUMAN relationship: has_participant CCO:B0058982 ! TA2R4_HUMAN relationship: has_participant CCO:B0058983 ! TA2R3_HUMAN relationship: has_participant CCO:B0058984 ! TA2R1_HUMAN relationship: has_participant CCO:B0058993 ! GPC5D_HUMAN relationship: has_participant CCO:B0058996 ! GPC5B_HUMAN relationship: has_participant CCO:B0059007 ! OR6C3_HUMAN relationship: has_participant CCO:B0059008 ! OR6C2_HUMAN relationship: has_participant CCO:B0059038 ! TAAR3_HUMAN relationship: has_participant CCO:B0059039 ! TAAR2_HUMAN relationship: has_participant CCO:B0059040 ! OR1A1_HUMAN relationship: has_participant CCO:B0059044 ! Q9P1V4_HUMAN relationship: has_participant CCO:B0059055 ! C5ARL_HUMAN relationship: has_participant CCO:B0059061 ! GBG13_HUMAN relationship: has_participant CCO:B0059074 ! XPR1_HUMAN relationship: has_participant CCO:B0059075 ! GBG12_HUMAN relationship: has_participant CCO:B0059102 ! Q9UDD7_HUMAN relationship: has_participant CCO:B0059120 ! O14J1_HUMAN relationship: has_participant CCO:B0059121 ! OR5V1_HUMAN relationship: has_participant CCO:B0059122 ! O12D3_HUMAN relationship: has_participant CCO:B0059150 ! RPGFL_HUMAN relationship: has_participant CCO:B0059152 ! EMR2_HUMAN relationship: has_participant CCO:B0059168 ! GP160_HUMAN relationship: has_participant CCO:B0059169 ! Q9UJ49_HUMAN relationship: has_participant CCO:B0059182 ! GBG8_HUMAN relationship: has_participant CCO:B0059195 ! O52A1_HUMAN relationship: has_participant CCO:B0059199 ! UR2R_HUMAN relationship: has_participant CCO:B0059212 ! Q9UL14_HUMAN relationship: has_participant CCO:B0059220 ! Q9ULA3_HUMAN relationship: has_participant CCO:B0059233 ! FZD4_HUMAN relationship: has_participant CCO:B0059240 ! Q9UM77_HUMAN relationship: has_participant CCO:B0059259 ! GPR34_HUMAN relationship: has_participant CCO:B0059260 ! Q9UPH3_HUMAN relationship: has_participant CCO:B0059295 ! RASD1_HUMAN relationship: has_participant CCO:B0059316 ! GPR52_HUMAN relationship: has_participant CCO:B0059317 ! GPR55_HUMAN relationship: has_participant CCO:B0059331 ! Q9Y347_HUMAN relationship: has_participant CCO:B0059337 ! GBG5L_HUMAN relationship: has_participant CCO:B0059341 ! OR2W1_HUMAN relationship: has_participant CCO:B0059356 ! O10H1_HUMAN relationship: has_participant CCO:B0059374 ! OR1A2_HUMAN relationship: has_participant CCO:B0059379 ! HRH3_HUMAN relationship: has_participant CCO:B0059380 ! O51B4_HUMAN relationship: has_participant CCO:B0059381 ! O51B2_HUMAN relationship: has_participant CCO:B0059392 ! NPFF2_HUMAN relationship: has_participant CCO:B0059393 ! GPR44_HUMAN relationship: has_participant CCO:B0059397 ! GPR56_HUMAN [Term] id: CCO:P0000727 name: G-protein signaling, coupled to cyclic nucleotide second messenger namespace: biological_process def: "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide." [GOC:mah, ISBN:0815316194] synonym: "G protein signaling, coupled to cyclic nucleotide second messenger" EXACT [] synonym: "G protein signalling, coupled to cyclic nucleotide second messenger" EXACT [] synonym: "G-protein signalling, coupled to cyclic nucleotide second messenger" EXACT [] xref: GO:0007187 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway is_a: CCO:P0001151 ! cyclic-nucleotide-mediated signaling relationship: has_participant CCO:B0005723 ! MTR1A_HUMAN relationship: has_participant CCO:B0005724 ! MTR1B_HUMAN relationship: has_participant CCO:B0021417 ! CALRL_HUMAN relationship: has_participant CCO:B0030552 ! MC3R_HUMAN relationship: has_participant CCO:B0030561 ! MSHR_HUMAN relationship: has_participant CCO:B0030569 ! MC5R_HUMAN relationship: has_participant CCO:B0030577 ! ACTHR_HUMAN relationship: has_participant CCO:B0038262 ! HRH2_HUMAN relationship: has_participant CCO:B0038266 ! 5HT1D_HUMAN relationship: has_participant CCO:B0038965 ! CCL2_HUMAN relationship: has_participant CCO:B0050753 ! OPRD_HUMAN relationship: has_participant CCO:B0050755 ! SSR2_HUMAN relationship: has_participant CCO:B0050785 ! SSR5_HUMAN relationship: has_participant CCO:B0050788 ! SSR1_HUMAN relationship: has_participant CCO:B0050793 ! SSR4_HUMAN relationship: has_participant CCO:B0050794 ! SSR3_HUMAN relationship: has_participant CCO:B0054851 ! NPY_HUMAN relationship: has_participant CCO:B0054923 ! ACM2_HUMAN relationship: has_participant CCO:B0055020 ! ADRB3_HUMAN relationship: has_participant CCO:B0055054 ! TSHR_HUMAN relationship: has_participant CCO:B0055133 ! CNR1_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055152 ! LSHR_HUMAN relationship: has_participant CCO:B0055187 ! NPY1R_HUMAN relationship: has_participant CCO:B0055197 ! 5HT1B_HUMAN relationship: has_participant CCO:B0055205 ! 5HT1E_HUMAN relationship: has_participant CCO:B0055226 ! 5HT1F_HUMAN relationship: has_participant CCO:B0055253 ! VIPR1_HUMAN relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055272 ! 5HT7R_HUMAN relationship: has_participant CCO:B0055273 ! CNR2_HUMAN relationship: has_participant CCO:B0055360 ! PI2R_HUMAN relationship: has_participant CCO:B0055374 ! XCR1_HUMAN relationship: has_participant CCO:B0055449 ! 5HT6R_HUMAN relationship: has_participant CCO:B0055724 ! PTHR1_HUMAN relationship: has_participant CCO:B0055937 ! 5HT4R_HUMAN relationship: has_participant CCO:B0059379 ! HRH3_HUMAN [Term] id: CCO:P0000728 name: G-protein signaling, coupled to cAMP nucleotide second messenger namespace: biological_process def: "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by modulation of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP." [GOC:mah, ISBN:0815316194] synonym: "G protein signaling, coupled to cAMP nucleotide second messenger" EXACT [] synonym: "G protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT [] synonym: "G protein signalling, coupled to cAMP nucleotide second messenger" EXACT [] synonym: "G protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT [] synonym: "G-protein signaling, coupled to cyclic AMP nucleotide second messenger" EXACT [] synonym: "G-protein signalling, coupled to cAMP nucleotide second messenger" EXACT [] synonym: "G-protein signalling, coupled to cyclic AMP nucleotide second messenger" EXACT [] xref: GO:0007188 is_a: CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger is_a: CCO:P0001149 ! cAMP-mediated signaling relationship: has_participant CCO:B0015122 ! GLR_HUMAN relationship: has_participant CCO:B0015134 ! GLP2R_HUMAN relationship: has_participant CCO:B0018534 ! KAPCB_HUMAN relationship: has_participant CCO:B0027200 ! FPR1_HUMAN relationship: has_participant CCO:B0030574 ! MC4R_HUMAN relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN relationship: has_participant CCO:B0038265 ! ADA1D_HUMAN relationship: has_participant CCO:B0054498 ! GALR2_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054923 ! ACM2_HUMAN relationship: has_participant CCO:B0055020 ! ADRB3_HUMAN relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN relationship: has_participant CCO:B0055219 ! V2R_HUMAN relationship: has_participant CCO:B0055271 ! GRK5_HUMAN relationship: has_participant CCO:B0055276 ! CRFR1_HUMAN relationship: has_participant CCO:B0055288 ! PE2R4_HUMAN relationship: has_participant CCO:B0055472 ! CCR3_HUMAN relationship: has_participant CCO:B0055694 ! CAC1D_HUMAN relationship: has_participant CCO:B0055898 ! CRFR2_HUMAN relationship: has_participant CCO:B0058675 ! P2Y12_HUMAN relationship: has_participant CCO:B0059418 ! WASF2_HUMAN [Term] id: CCO:P0000729 name: G-protein signaling, adenylate cyclase activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP." [GOC:mah, ISBN:0815316194] synonym: "G protein signaling, adenylate cyclase activating pathway" EXACT [] synonym: "G protein signaling, adenylyl cyclase activating pathway" EXACT [] synonym: "G protein signalling, adenylate cyclase activating pathway" EXACT [] synonym: "G protein signalling, adenylyl cyclase activating pathway" EXACT [] synonym: "G-protein signaling, adenylyl cyclase activating pathway" EXACT [] synonym: "G-protein signalling, adenylate cyclase activating pathway" EXACT [] synonym: "G-protein signalling, adenylyl cyclase activating pathway" EXACT [] xref: GO:0007189 is_a: CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: has_participant CCO:B0021417 ! CALRL_HUMAN relationship: has_participant CCO:B0027558 ! Q14455_HUMAN relationship: has_participant CCO:B0054765 ! GNAS3_HUMAN relationship: has_participant CCO:B0054813 ! S1PR4_HUMAN relationship: has_participant CCO:B0054847 ! PTHY_HUMAN relationship: has_participant CCO:B0054850 ! SLIB_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054929 ! ADRB1_HUMAN relationship: has_participant CCO:B0054999 ! PTHR_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055140 ! DRD5_HUMAN relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN relationship: has_participant CCO:B0055230 ! CALCR_HUMAN relationship: has_participant CCO:B0055372 ! GPR3_HUMAN relationship: has_participant CCO:B0055419 ! PTH2R_HUMAN relationship: has_participant CCO:B0058126 ! UCN3_HUMAN [Term] id: CCO:P0000730 name: dopamine receptor, adenylate cyclase activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, followed by activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP." [GOC:mah] synonym: "dopamine receptor, adenylyl cyclase activating pathway" EXACT [] xref: GO:0007191 is_a: CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway is_a: CCO:P0000747 ! dopamine receptor signaling pathway relationship: has_participant CCO:B0027551 ! GNAL_HUMAN relationship: has_participant CCO:B0054773 ! ADCY5_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055140 ! DRD5_HUMAN [Term] id: CCO:P0000731 name: serotonin receptor, adenylate cyclase activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, followed by activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP." [GOC:mah] synonym: "serotonin receptor, adenylyl cyclase activating pathway" EXACT [] xref: GO:0007192 is_a: CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway [Term] id: CCO:P0000732 name: G-protein signaling, adenylate cyclase inhibiting pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP." [GOC:mah, ISBN:0815316194] synonym: "G protein signaling, adenylate cyclase inhibiting pathway" EXACT [] synonym: "G protein signaling, adenylyl cyclase inhibiting pathway" EXACT [] synonym: "G protein signalling, adenylate cyclase inhibiting pathway" EXACT [] synonym: "G protein signalling, adenylyl cyclase inhibiting pathway" EXACT [] synonym: "G-protein signaling, adenylyl cyclase inhibiting pathway" EXACT [] synonym: "G-protein signalling, adenylate cyclase inhibiting pathway" EXACT [] synonym: "G-protein signalling, adenylyl cyclase inhibiting pathway" EXACT [] xref: GO:0007193 is_a: CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger relationship: has_participant CCO:B0020780 ! RGS1_HUMAN relationship: has_participant CCO:B0050753 ! OPRD_HUMAN relationship: has_participant CCO:B0050755 ! SSR2_HUMAN relationship: has_participant CCO:B0050758 ! OPRK_HUMAN relationship: has_participant CCO:B0050781 ! OPRX_HUMAN relationship: has_participant CCO:B0055086 ! ANPRC_HUMAN relationship: has_participant CCO:B0055187 ! NPY1R_HUMAN relationship: has_participant CCO:B0055418 ! NPY2R_HUMAN relationship: has_participant CCO:B0058418 ! S1PR3_HUMAN relationship: has_participant CCO:B0058444 ! MCHR1_HUMAN relationship: has_participant CCO:B0059393 ! GPR44_HUMAN [Term] id: CCO:P0000733 name: dopamine receptor, adenylate cyclase inhibiting pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP." [GOC:mah] synonym: "dopamine receptor, adenylyl cyclase inhibiting pathway" EXACT [] xref: GO:0007195 is_a: CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway is_a: CCO:P0000747 ! dopamine receptor signaling pathway relationship: has_participant CCO:B0054773 ! ADCY5_HUMAN relationship: has_participant CCO:B0055024 ! DRD2_HUMAN [Term] id: CCO:P0000734 name: metabotropic glutamate receptor, adenylate cyclase inhibiting pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a metabotropic glutamate receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP." [GOC:mah] synonym: "metabotropic glutamate receptor, adenylyl cyclase inhibiting pathway" EXACT [] xref: GO:0007196 is_a: CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway is_a: CCO:P0000751 ! metabotropic glutamate receptor signaling pathway relationship: has_participant CCO:B0042225 ! GRM4_HUMAN [Term] id: CCO:P0000735 name: muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP." [GOC:mah] synonym: "muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway" EXACT [] xref: GO:0007197 is_a: CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway relationship: has_participant CCO:B0054936 ! ACM5_HUMAN [Term] id: CCO:P0000736 name: serotonin receptor, adenylate cyclase inhibiting pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP." [GOC:mah] synonym: "serotonin receptor, adenylyl cyclase inhibiting pathway" EXACT [] xref: GO:0007198 is_a: CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway [Term] id: CCO:P0000737 name: G-protein signaling, coupled to cGMP nucleotide second messenger namespace: biological_process def: "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase and a subsequent increase in the concentration of cyclic GMP." [GOC:mah, ISBN:0815316194] synonym: "G protein signaling, coupled to cGMP nucleotide second messenger" EXACT [] synonym: "G protein signalling, coupled to cGMP nucleotide second messenger" EXACT [] synonym: "G-protein signalling, coupled to cGMP nucleotide second messenger" EXACT [] xref: GO:0007199 is_a: CCO:P0000727 ! G-protein signaling, coupled to cyclic nucleotide second messenger is_a: CCO:P0001150 ! cGMP-mediated signaling relationship: has_participant CCO:B0006309 ! TBL3_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN [Term] id: CCO:P0000738 name: G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) namespace: biological_process def: "The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate." [GOC:mah, ISBN:0815316194] synonym: "G protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] synonym: "G protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] synonym: "G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] xref: GO:0007200 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway is_a: CCO:P0002761 ! phosphoinositide-mediated signaling relationship: has_participant CCO:B0018697 ! EDNRB_HUMAN relationship: has_participant CCO:B0030552 ! MC3R_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0049157 ! PAR4_HUMAN relationship: has_participant CCO:B0049457 ! NK1R_HUMAN relationship: has_participant CCO:B0054503 ! OX2R_HUMAN relationship: has_participant CCO:B0055086 ! ANPRC_HUMAN relationship: has_participant CCO:B0055176 ! CXCR2_HUMAN relationship: has_participant CCO:B0055201 ! NMBR_HUMAN relationship: has_participant CCO:B0055223 ! AGTR1_HUMAN relationship: has_participant CCO:B0055225 ! GNA15_HUMAN relationship: has_participant CCO:B0055251 ! CCKAR_HUMAN relationship: has_participant CCO:B0055252 ! GASR_HUMAN relationship: has_participant CCO:B0055287 ! HRH1_HUMAN relationship: has_participant CCO:B0055338 ! P2RY2_HUMAN relationship: has_participant CCO:B0055343 ! 5HT2B_HUMAN relationship: has_participant CCO:B0055394 ! P2RY1_HUMAN relationship: has_participant CCO:B0055419 ! PTH2R_HUMAN relationship: has_participant CCO:B0055469 ! P2RY4_HUMAN relationship: has_participant CCO:B0056042 ! P2RY6_HUMAN relationship: has_participant CCO:B0056100 ! LT4R1_HUMAN relationship: has_participant CCO:B0056730 ! GP139_HUMAN relationship: has_participant CCO:B0058213 ! P2Y11_HUMAN relationship: has_participant CCO:B0058632 ! NMUR2_HUMAN relationship: has_participant CCO:B0058780 ! NMUR1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059061 ! GBG13_HUMAN [Term] id: CCO:P0000739 name: activation of phospholipase C activity namespace: biological_process def: "The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand." [GOC:dph, GOC:mah, GOC:tb, PMID:8280098] comment: Note that this term refers to a signaling pathway, and should not be confused with function terms such as 'phospholipase activator activity ; GO:0016004'. synonym: "phospholipase C activation" EXACT [GOC:dph, GOC:tb] xref: GO:0007202 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN relationship: has_participant CCO:B0018695 ! EDNRA_HUMAN relationship: has_participant CCO:B0043866 ! LPAR2_HUMAN relationship: has_participant CCO:B0054813 ! S1PR4_HUMAN relationship: has_participant CCO:B0055137 ! C5AR_HUMAN relationship: has_participant CCO:B0055225 ! GNA15_HUMAN relationship: has_participant CCO:B0055252 ! GASR_HUMAN relationship: has_participant CCO:B0055318 ! V1AR_HUMAN relationship: has_participant CCO:B0055395 ! V1BR_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: has_participant CCO:B0058076 ! LPAR1_HUMAN relationship: has_participant CCO:B0058780 ! NMUR1_HUMAN relationship: part_of CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:P0000740 name: activation of protein kinase C activity namespace: biological_process def: "The initiation of the activity of the inactive enzyme protein kinase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand." [GOC:mah] synonym: "PKC activation" EXACT [] synonym: "protein kinase C activation" EXACT [GOC:dph, GOC:tb] xref: GO:0007205 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0020756 ! Q96GK1_HUMAN relationship: has_participant CCO:B0020760 ! Q8N632_HUMAN relationship: has_participant CCO:B0036431 ! SPHK2_HUMAN relationship: has_participant CCO:B0036434 ! A0T4C8_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0054103 ! A8MXU2_HUMAN relationship: has_participant CCO:B0054344 ! LPP1_HUMAN relationship: has_participant CCO:B0054677 ! DGKI_HUMAN relationship: has_participant CCO:B0054699 ! KPCD3_HUMAN relationship: has_participant CCO:B0054986 ! ACM1_HUMAN relationship: has_participant CCO:B0055091 ! NEUM_HUMAN relationship: has_participant CCO:B0055114 ! CAP7_HUMAN relationship: has_participant CCO:B0055125 ! EDN2_HUMAN relationship: has_participant CCO:B0055162 ! DGKA_HUMAN relationship: has_participant CCO:B0055425 ! DGKG_HUMAN relationship: has_participant CCO:B0055485 ! DGKE_HUMAN relationship: has_participant CCO:B0055503 ! DGKQ_HUMAN relationship: has_participant CCO:B0055932 ! DGKZ_HUMAN relationship: has_participant CCO:B0056176 ! DGKD_HUMAN relationship: has_participant CCO:B0056204 ! Q2M1H4_HUMAN relationship: has_participant CCO:B0056307 ! CERKL_HUMAN relationship: has_participant CCO:B0056362 ! AGK_HUMAN relationship: has_participant CCO:B0056385 ! Q59F26_HUMAN relationship: has_participant CCO:B0056403 ! Q59GE2_HUMAN relationship: has_participant CCO:B0056428 ! Q5FWG1_HUMAN relationship: has_participant CCO:B0056515 ! DGKK_HUMAN relationship: has_participant CCO:B0057063 ! Q6ZT25_HUMAN relationship: has_participant CCO:B0057186 ! Q7Z5X8_HUMAN relationship: has_participant CCO:B0057292 ! DGKH_HUMAN relationship: has_participant CCO:B0057350 ! Q8IVW9_HUMAN relationship: has_participant CCO:B0057916 ! CERK1_HUMAN relationship: has_participant CCO:B0058919 ! CISH_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059417 ! DGKB_HUMAN relationship: part_of CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:P0000741 name: metabotropic glutamate receptor, phospholipase C activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a metabotropic glutamate receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate." [GOC:mah] xref: GO:0007206 is_a: CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) is_a: CCO:P0000751 ! metabotropic glutamate receptor signaling pathway relationship: has_participant CCO:B0042230 ! GRM5_HUMAN relationship: has_participant CCO:B0057307 ! HOME1_HUMAN [Term] id: CCO:P0000742 name: muscarinic acetylcholine receptor, phospholipase C activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate." [GOC:mah] xref: GO:0007207 is_a: CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: has_participant CCO:B0054923 ! ACM2_HUMAN relationship: has_participant CCO:B0054986 ! ACM1_HUMAN relationship: has_participant CCO:B0055225 ! GNA15_HUMAN [Term] id: CCO:P0000743 name: serotonin receptor, phospholipase C activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate." [GOC:mah] xref: GO:0007208 is_a: CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: has_participant CCO:B0055198 ! 5HT2A_HUMAN [Term] id: CCO:P0000744 name: tachykinin receptor, phospholipase C activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate." [GOC:mah] xref: GO:0007209 is_a: CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:P0000745 name: serotonin receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands." [GOC:mah] synonym: "serotonin receptor signalling pathway" EXACT [] xref: GO:0007210 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0055198 ! 5HT2A_HUMAN [Term] id: CCO:P0000746 name: octopamine/tyramine signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of an octopamine/tyramine receptor binding to one of its physiological ligands." [GOC:mah] synonym: "octopamine/tyramine signalling pathway" EXACT [] xref: GO:0007211 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0000747 name: dopamine receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:mah] synonym: "dopamine receptor signalling pathway" EXACT [] xref: GO:0007212 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0055024 ! DRD2_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055139 ! DRD4_HUMAN relationship: has_participant CCO:B0055293 ! DRD3_HUMAN relationship: has_participant CCO:B0055356 ! NSG1_HUMAN relationship: has_participant CCO:B0058557 ! KLF16_HUMAN relationship: has_participant CCO:B0058986 ! CALY_HUMAN relationship: has_participant CCO:B0059328 ! NSG2_HUMAN [Term] id: CCO:P0000748 name: acetylcholine receptor signaling, muscarinic pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a muscarinic acetylcholine receptor binding to one of its physiological ligands; muscarinic acetylcholine receptors activate inhibitory G proteins and can be activated by the fungal alkaloid muscarine." [GOC:mah, ISBN:0815316194] synonym: "acetylcholine receptor signalling, muscarinic pathway" EXACT [] xref: GO:0007213 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN relationship: has_participant CCO:B0005949 ! AGRIN_HUMAN relationship: has_participant CCO:B0054923 ! ACM2_HUMAN relationship: has_participant CCO:B0054924 ! ACM4_HUMAN relationship: has_participant CCO:B0054936 ! ACM5_HUMAN relationship: has_participant CCO:B0054986 ! ACM1_HUMAN relationship: has_participant CCO:B0055180 ! ARBK1_HUMAN relationship: has_participant CCO:B0055621 ! GBB1_HUMAN [Term] id: CCO:P0000749 name: gamma-aminobutyric acid signaling pathway namespace: biological_process def: "The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor." [GOC:mah] synonym: "4-aminobutanoate signaling pathway" EXACT [] synonym: "4-aminobutanoate signalling pathway" EXACT [] synonym: "4-aminobutyrate signaling pathway" EXACT [] synonym: "4-aminobutyrate signalling pathway" EXACT [] synonym: "GABA signaling pathway" EXACT [] synonym: "GABA signalling pathway" EXACT [] synonym: "gamma-aminobutyric acid signalling pathway" EXACT [] xref: GO:0007214 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0006317 ! GABR1_HUMAN relationship: has_participant CCO:B0022898 ! GBRA4_HUMAN relationship: has_participant CCO:B0022899 ! GBRR2_HUMAN relationship: has_participant CCO:B0022900 ! GBRG3_HUMAN relationship: has_participant CCO:B0022901 ! GBRE_HUMAN relationship: has_participant CCO:B0022902 ! Q8IYR7_HUMAN relationship: has_participant CCO:B0022906 ! GBRG1_HUMAN relationship: has_participant CCO:B0022907 ! GBRA6_HUMAN relationship: has_participant CCO:B0022908 ! Q5H9T8_HUMAN relationship: has_participant CCO:B0022909 ! GBRG2_HUMAN relationship: has_participant CCO:B0022914 ! GBRA1_HUMAN relationship: has_participant CCO:B0022915 ! GBRA5_HUMAN relationship: has_participant CCO:B0022924 ! GBRA2_HUMAN relationship: has_participant CCO:B0022926 ! GBRR1_HUMAN relationship: has_participant CCO:B0022933 ! GBRA3_HUMAN relationship: has_participant CCO:B0022935 ! Q6PCC3_HUMAN relationship: has_participant CCO:B0027056 ! A8MWU7_HUMAN relationship: has_participant CCO:B0027058 ! A8MX51_HUMAN relationship: has_participant CCO:B0039233 ! GBRB2_HUMAN relationship: has_participant CCO:B0041922 ! GABR2_HUMAN [Term] id: CCO:P0000750 name: glutamate signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor." [GOC:mah, PMID:9131252] synonym: "glutamate signalling pathway" EXACT [] xref: GO:0007215 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0020605 ! GRIK3_HUMAN relationship: has_participant CCO:B0020611 ! GRIK2_HUMAN relationship: has_participant CCO:B0020614 ! GRIK1_HUMAN relationship: has_participant CCO:B0020617 ! GRIK4_HUMAN relationship: has_participant CCO:B0020622 ! GRIA3_HUMAN relationship: has_participant CCO:B0020623 ! GRIA4_HUMAN relationship: has_participant CCO:B0033427 ! NMDE1_HUMAN relationship: has_participant CCO:B0033431 ! NMDE2_HUMAN relationship: has_participant CCO:B0050788 ! SSR1_HUMAN relationship: has_participant CCO:B0054481 ! GRID2_HUMAN [Term] id: CCO:P0000751 name: metabotropic glutamate receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor coupled to effectors through GTP-binding proteins." [GOC:mah, PMID:9131252] synonym: "metabotropic glutamate receptor signalling pathway" EXACT [] xref: GO:0007216 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway is_a: CCO:P0000750 ! glutamate signaling pathway relationship: has_participant CCO:B0042244 ! GRM6_HUMAN relationship: has_participant CCO:B0058913 ! HOME2_HUMAN relationship: has_participant CCO:B0058915 ! HOME3_HUMAN [Term] id: CCO:P0000752 name: tachykinin signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a tachykinin, i.e. a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2), binding to a cell surface receptor." [GOC:mah, PMID:14723970] synonym: "tachykinin signalling pathway" EXACT [] xref: GO:0007217 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0006242 ! TKNK_HUMAN relationship: has_participant CCO:B0049452 ! NK2R_HUMAN relationship: has_participant CCO:B0049455 ! NK3R_HUMAN relationship: has_participant CCO:B0049457 ! NK1R_HUMAN relationship: has_participant CCO:B0055119 ! TKN1_HUMAN relationship: has_participant CCO:B0055180 ! ARBK1_HUMAN relationship: has_participant CCO:B0055271 ! GRK5_HUMAN relationship: has_participant CCO:B0057168 ! Q7Z4W6_HUMAN [Term] id: CCO:P0000753 name: neuropeptide signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor." [GOC:mah, ISBN:0815316194] synonym: "neuropeptide signalling pathway" EXACT [] xref: GO:0007218 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0005546 ! CELR3_HUMAN relationship: has_participant CCO:B0006081 ! CBPE_HUMAN relationship: has_participant CCO:B0006242 ! TKNK_HUMAN relationship: has_participant CCO:B0017123 ! PROK2_HUMAN relationship: has_participant CCO:B0021202 ! A2A3C6_HUMAN relationship: has_participant CCO:B0021203 ! A2A3C1_HUMAN relationship: has_participant CCO:B0021206 ! A2A3C4_HUMAN relationship: has_participant CCO:B0021208 ! A2A3C2_HUMAN relationship: has_participant CCO:B0021209 ! A2A3C3_HUMAN relationship: has_participant CCO:B0021210 ! BAI2_HUMAN relationship: has_participant CCO:B0022911 ! GLRB_HUMAN relationship: has_participant CCO:B0022913 ! GLRA1_HUMAN relationship: has_participant CCO:B0022917 ! GLRA2_HUMAN relationship: has_participant CCO:B0026865 ! SORC1_HUMAN relationship: has_participant CCO:B0026866 ! SORC3_HUMAN relationship: has_participant CCO:B0026867 ! SORC2_HUMAN relationship: has_participant CCO:B0032345 ! Q5Y190_HUMAN relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0033402 ! Q14CE0_HUMAN relationship: has_participant CCO:B0033403 ! Q6F3F5_HUMAN relationship: has_participant CCO:B0033404 ! Q6F3F6_HUMAN relationship: has_participant CCO:B0033405 ! GP126_HUMAN relationship: has_participant CCO:B0033406 ! A2A2J1_HUMAN relationship: has_participant CCO:B0033407 ! A2A2J2_HUMAN relationship: has_participant CCO:B0033410 ! A9Z1X2_HUMAN relationship: has_participant CCO:B0033411 ! Q6F3F8_HUMAN relationship: has_participant CCO:B0033412 ! GP112_HUMAN relationship: has_participant CCO:B0033414 ! Q499H0_HUMAN relationship: has_participant CCO:B0033415 ! Q5EGP2_HUMAN relationship: has_participant CCO:B0033418 ! GPR64_HUMAN relationship: has_participant CCO:B0033419 ! Q6F3F7_HUMAN relationship: has_participant CCO:B0037954 ! 7B2_HUMAN relationship: has_participant CCO:B0050753 ! OPRD_HUMAN relationship: has_participant CCO:B0050755 ! SSR2_HUMAN relationship: has_participant CCO:B0050788 ! SSR1_HUMAN relationship: has_participant CCO:B0050793 ! SSR4_HUMAN relationship: has_participant CCO:B0053781 ! A6MW40_HUMAN relationship: has_participant CCO:B0053800 ! A6NE11_HUMAN relationship: has_participant CCO:B0053827 ! A6NG39_HUMAN relationship: has_participant CCO:B0053865 ! A6NIT7_HUMAN relationship: has_participant CCO:B0053959 ! A8K2Y6_HUMAN relationship: has_participant CCO:B0053966 ! A8K4E4_HUMAN relationship: has_participant CCO:B0053973 ! A8K6W1_HUMAN relationship: has_participant CCO:B0054001 ! A8MQV3_HUMAN relationship: has_participant CCO:B0054018 ! A8MSZ9_HUMAN relationship: has_participant CCO:B0054049 ! A8MUW4_HUMAN relationship: has_participant CCO:B0054136 ! A8MZ46_HUMAN relationship: has_participant CCO:B0054241 ! B1ALU1_HUMAN relationship: has_participant CCO:B0054242 ! B1ALU2_HUMAN relationship: has_participant CCO:B0054243 ! B1ALU3_HUMAN relationship: has_participant CCO:B0054244 ! B1ALU4_HUMAN relationship: has_participant CCO:B0054245 ! B1ALU5_HUMAN relationship: has_participant CCO:B0054246 ! B1ALU6_HUMAN relationship: has_participant CCO:B0054278 ! B1AWB3_HUMAN relationship: has_participant CCO:B0054279 ! B1AWB4_HUMAN relationship: has_participant CCO:B0054280 ! B1AWB6_HUMAN relationship: has_participant CCO:B0054281 ! B1AWB7_HUMAN relationship: has_participant CCO:B0054303 ! AGRP_HUMAN relationship: has_participant CCO:B0054348 ! BAI1_HUMAN relationship: has_participant CCO:B0054409 ! NPFF_HUMAN relationship: has_participant CCO:B0054501 ! OREX_HUMAN relationship: has_participant CCO:B0054502 ! OX1R_HUMAN relationship: has_participant CCO:B0054503 ! OX2R_HUMAN relationship: has_participant CCO:B0054536 ! BAI3_HUMAN relationship: has_participant CCO:B0054576 ! GALR3_HUMAN relationship: has_participant CCO:B0054710 ! LPHN1_HUMAN relationship: has_participant CCO:B0054728 ! NXPH2_HUMAN relationship: has_participant CCO:B0054729 ! NXPH3_HUMAN relationship: has_participant CCO:B0054730 ! NXPH4_HUMAN relationship: has_participant CCO:B0054767 ! LPHN2_HUMAN relationship: has_participant CCO:B0054781 ! ECEL1_HUMAN relationship: has_participant CCO:B0054836 ! PENK_HUMAN relationship: has_participant CCO:B0054837 ! PDYN_HUMAN relationship: has_participant CCO:B0054845 ! CALC_HUMAN relationship: has_participant CCO:B0054851 ! NPY_HUMAN relationship: has_participant CCO:B0054913 ! GRP_HUMAN relationship: has_participant CCO:B0054938 ! NMB_HUMAN relationship: has_participant CCO:B0054954 ! NPS_HUMAN relationship: has_participant CCO:B0055119 ! TKN1_HUMAN relationship: has_participant CCO:B0055120 ! MCH_HUMAN relationship: has_participant CCO:B0055148 ! GALA_HUMAN relationship: has_participant CCO:B0055382 ! GALR1_HUMAN relationship: has_participant CCO:B0055409 ! NMU_HUMAN relationship: has_participant CCO:B0055413 ! CD97_HUMAN relationship: has_participant CCO:B0055661 ! OX26_HUMAN relationship: has_participant CCO:B0055670 ! PKD1_HUMAN relationship: has_participant CCO:B0055813 ! Q0IJ52_HUMAN relationship: has_participant CCO:B0055923 ! PNOC_HUMAN relationship: has_participant CCO:B0055975 ! EMR1_HUMAN relationship: has_participant CCO:B0056046 ! Q15142_HUMAN relationship: has_participant CCO:B0056152 ! CART_HUMAN relationship: has_participant CCO:B0056221 ! Q2PNZ1_HUMAN relationship: has_participant CCO:B0056268 ! Q3SXL4_HUMAN relationship: has_participant CCO:B0056311 ! Q4G0K7_HUMAN relationship: has_participant CCO:B0056361 ! Q53GP0_HUMAN relationship: has_participant CCO:B0056368 ! Q53YA0_HUMAN relationship: has_participant CCO:B0056397 ! Q59G72_HUMAN relationship: has_participant CCO:B0056430 ! NMS_HUMAN relationship: has_participant CCO:B0056446 ! Q5IFH6_HUMAN relationship: has_participant CCO:B0056517 ! Q5KU19_HUMAN relationship: has_participant CCO:B0056518 ! Q5KU20_HUMAN relationship: has_participant CCO:B0056520 ! Q5KU22_HUMAN relationship: has_participant CCO:B0056586 ! GP110_HUMAN relationship: has_participant CCO:B0056694 ! Q658W4_HUMAN relationship: has_participant CCO:B0056934 ! GP133_HUMAN relationship: has_participant CCO:B0056978 ! Q6ZMK5_HUMAN relationship: has_participant CCO:B0056984 ! Q6ZMN0_HUMAN relationship: has_participant CCO:B0056986 ! Q6ZMP1_HUMAN relationship: has_participant CCO:B0057028 ! YP009_HUMAN relationship: has_participant CCO:B0057068 ! Q6ZT94_HUMAN relationship: has_participant CCO:B0057084 ! Q6ZVJ0_HUMAN relationship: has_participant CCO:B0057159 ! PK1L2_HUMAN relationship: has_participant CCO:B0057160 ! PK1L3_HUMAN relationship: has_participant CCO:B0057220 ! GP144_HUMAN relationship: has_participant CCO:B0057232 ! EMR4_HUMAN relationship: has_participant CCO:B0057300 ! GPR97_HUMAN relationship: has_participant CCO:B0057361 ! GP125_HUMAN relationship: has_participant CCO:B0057373 ! Q8IXE4_HUMAN relationship: has_participant CCO:B0057402 ! GP116_HUMAN relationship: has_participant CCO:B0057403 ! GP115_HUMAN relationship: has_participant CCO:B0057404 ! GP114_HUMAN relationship: has_participant CCO:B0057405 ! GP113_HUMAN relationship: has_participant CCO:B0057406 ! GP111_HUMAN relationship: has_participant CCO:B0057497 ! NPW_HUMAN relationship: has_participant CCO:B0057612 ! NPB_HUMAN relationship: has_participant CCO:B0057637 ! Q8NGA9_HUMAN relationship: has_participant CCO:B0057936 ! Q8TDT4_HUMAN relationship: has_participant CCO:B0058018 ! GPR98_HUMAN relationship: has_participant CCO:B0058148 ! TIP39_HUMAN relationship: has_participant CCO:B0058255 ! GP128_HUMAN relationship: has_participant CCO:B0058329 ! GP124_HUMAN relationship: has_participant CCO:B0058421 ! SORT_HUMAN relationship: has_participant CCO:B0058444 ! MCHR1_HUMAN relationship: has_participant CCO:B0058565 ! EMR3_HUMAN relationship: has_participant CCO:B0058632 ! NMUR2_HUMAN relationship: has_participant CCO:B0058766 ! LPHN3_HUMAN relationship: has_participant CCO:B0058780 ! NMUR1_HUMAN relationship: has_participant CCO:B0058793 ! ELTD1_HUMAN relationship: has_participant CCO:B0058817 ! RFRP_HUMAN relationship: has_participant CCO:B0058922 ! Q9NSM3_HUMAN relationship: has_participant CCO:B0058968 ! CELR1_HUMAN relationship: has_participant CCO:B0059066 ! GALP_HUMAN relationship: has_participant CCO:B0059139 ! PCSK1_HUMAN relationship: has_participant CCO:B0059152 ! EMR2_HUMAN relationship: has_participant CCO:B0059397 ! GPR56_HUMAN [Term] id: CCO:P0000754 name: Notch signaling pathway namespace: biological_process def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell." [GOC:go_curators] synonym: "N signaling pathway" EXACT [] synonym: "N signalling pathway" EXACT [] synonym: "Notch receptor signaling pathway" EXACT [] synonym: "Notch receptor signalling pathway" EXACT [] synonym: "Notch signalling pathway" EXACT [] synonym: "Notch-receptor signaling pathway" EXACT [] synonym: "Notch-receptor signalling pathway" EXACT [] xref: GO:0007219 xref: GO:0030179 xref: Reactome:157118 xref: Reactome:212079 xref: Reactome:221837 xref: Reactome:230401 xref: Reactome:238447 xref: Reactome:244988 xref: Reactome:249867 xref: Reactome:286699 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0002245 ! JAG2_HUMAN relationship: has_participant CCO:B0005474 ! A4_HUMAN relationship: has_participant CCO:B0005712 ! ADA17_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0006042 ! MINT_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0017820 ! NOTC3_HUMAN relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0024312 ! DLL3_HUMAN relationship: has_participant CCO:B0028290 ! JAG1_HUMAN relationship: has_participant CCO:B0028291 ! DLL4_HUMAN relationship: has_participant CCO:B0028292 ! DLL1_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: has_participant CCO:B0049576 ! NRG1_HUMAN relationship: has_participant CCO:B0050490 ! NLE1_HUMAN relationship: has_participant CCO:B0050820 ! NT2NL_HUMAN relationship: has_participant CCO:B0054185 ! B0S882_HUMAN relationship: has_participant CCO:B0054191 ! B0V1X5_HUMAN relationship: has_participant CCO:B0054364 ! ADA10_HUMAN relationship: has_participant CCO:B0055439 ! PSN2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN relationship: has_participant CCO:B0055827 ! MESP2_HUMAN relationship: has_participant CCO:B0055851 ! CNTN1_HUMAN relationship: has_participant CCO:B0056532 ! Q5SPL1_HUMAN relationship: has_participant CCO:B0056538 ! Q5STG5_HUMAN relationship: has_participant CCO:B0057257 ! DTX2_HUMAN relationship: has_participant CCO:B0057298 ! DTX1_HUMAN relationship: has_participant CCO:B0057312 ! MIB1_HUMAN relationship: has_participant CCO:B0057409 ! MAML2_HUMAN relationship: has_participant CCO:B0057537 ! DTX3_HUMAN relationship: has_participant CCO:B0057608 ! DNER_HUMAN relationship: has_participant CCO:B0058000 ! APH1B_HUMAN relationship: has_participant CCO:B0058062 ! NICA_HUMAN relationship: has_participant CCO:B0058068 ! MAML1_HUMAN relationship: has_participant CCO:B0058158 ! MIB2_HUMAN relationship: has_participant CCO:B0058164 ! APH1A_HUMAN relationship: has_participant CCO:B0058242 ! MAML3_HUMAN relationship: has_participant CCO:B0058414 ! NOTC4_HUMAN relationship: has_participant CCO:B0058493 ! MESP1_HUMAN relationship: has_participant CCO:B0058576 ! HES7_HUMAN relationship: has_participant CCO:B0058628 ! WDR12_HUMAN relationship: has_participant CCO:B0058712 ! OFUT1_HUMAN relationship: has_participant CCO:B0058828 ! NDF4_HUMAN relationship: has_participant CCO:B0058865 ! HEYL_HUMAN relationship: has_participant CCO:B0058989 ! PEN2_HUMAN relationship: has_participant CCO:B0059081 ! HEY2_HUMAN relationship: has_participant CCO:B0059086 ! SE1L1_HUMAN relationship: has_participant CCO:B0059276 ! CNTN6_HUMAN relationship: has_participant CCO:B0059301 ! DTX4_HUMAN relationship: has_participant CCO:B0059378 ! HEY1_HUMAN [Term] id: CCO:P0000755 name: Notch receptor processing namespace: biological_process def: "The series of successive proteolytic cleavage events that take place after a Notch receptor binds a ligand, and which lead to the release of the Notch Intracellular Domain (NICD), which is the active form of the receptor." [PMID:12651094, PMID:14986688] synonym: "N receptor processing" EXACT [] xref: GO:0007220 xref: Reactome:156988 xref: Reactome:157212 xref: Reactome:211864 xref: Reactome:211871 xref: Reactome:221629 xref: Reactome:221636 xref: Reactome:230222 xref: Reactome:230229 xref: Reactome:238261 xref: Reactome:238268 xref: Reactome:244833 xref: Reactome:244840 xref: Reactome:249732 xref: Reactome:286586 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0055439 ! PSN2_HUMAN relationship: has_participant CCO:B0057608 ! DNER_HUMAN relationship: has_participant CCO:B0058062 ! NICA_HUMAN relationship: has_participant CCO:B0058164 ! APH1A_HUMAN relationship: has_participant CCO:B0058989 ! PEN2_HUMAN relationship: part_of CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:P0000756 name: positive regulation of transcription of Notch receptor target namespace: biological_process def: "The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain." [PMID:12651094] synonym: "N receptor target transcription factor activation" RELATED [] synonym: "Notch receptor target transcription factor activation" RELATED [] xref: GO:0007221 is_a: CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: part_of CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:P0000757 name: Wnt receptor signaling pathway, calcium modulating pathway namespace: biological_process def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:bf, GOC:dph, GOC:go_curators, PMID:11532397] synonym: "frizzled-2 signaling pathway" NARROW [] synonym: "frizzled-2 signalling pathway" NARROW [] synonym: "non-canonical Wnt signaling pathway" RELATED [] xref: GO:0007223 is_a: CCO:P0001111 ! Wnt receptor signaling pathway relationship: has_participant CCO:B0006047 ! WNT16_HUMAN relationship: has_participant CCO:B0053803 ! A6NE61_HUMAN relationship: has_participant CCO:B0053810 ! A6NEV2_HUMAN relationship: has_participant CCO:B0053953 ! A8K0G1_HUMAN relationship: has_participant CCO:B0054223 ! B1AJZ6_HUMAN relationship: has_participant CCO:B0054340 ! WN10B_HUMAN relationship: has_participant CCO:B0054341 ! WNT7A_HUMAN relationship: has_participant CCO:B0054388 ! WNT9A_HUMAN relationship: has_participant CCO:B0054389 ! WNT9B_HUMAN relationship: has_participant CCO:B0054822 ! WNT11_HUMAN relationship: has_participant CCO:B0054891 ! WNT1_HUMAN relationship: has_participant CCO:B0054945 ! WNT2_HUMAN relationship: has_participant CCO:B0055336 ! WNT5A_HUMAN relationship: has_participant CCO:B0055548 ! WNT3_HUMAN relationship: has_participant CCO:B0055549 ! WNT3A_HUMAN relationship: has_participant CCO:B0055550 ! WNT4_HUMAN relationship: has_participant CCO:B0055551 ! WNT7B_HUMAN relationship: has_participant CCO:B0055700 ! ROR2_HUMAN relationship: has_participant CCO:B0056271 ! Q3SY79_HUMAN relationship: has_participant CCO:B0056327 ! Q4VAJ4_HUMAN relationship: has_participant CCO:B0056399 ! Q59G81_HUMAN relationship: has_participant CCO:B0056513 ! Q5JYX2_HUMAN relationship: has_participant CCO:B0056613 ! Q5TEH8_HUMAN relationship: has_participant CCO:B0057051 ! Q6ZS96_HUMAN relationship: has_participant CCO:B0057057 ! Q6ZSP0_HUMAN relationship: has_participant CCO:B0057442 ! Q8N2D3_HUMAN relationship: has_participant CCO:B0058124 ! WNT2B_HUMAN relationship: has_participant CCO:B0058125 ! WNT8B_HUMAN relationship: has_participant CCO:B0058636 ! WN10A_HUMAN relationship: has_participant CCO:B0058665 ! WNT8A_HUMAN relationship: has_participant CCO:B0058666 ! WNT5B_HUMAN relationship: has_participant CCO:B0059405 ! WNT6_HUMAN [Term] id: CCO:P0000758 name: smoothened signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened." [GOC:mah, PMID:15205520] synonym: "hedgehog signaling pathway" EXACT [] synonym: "hh signaling pathway" EXACT [] synonym: "hh signalling pathway" EXACT [] synonym: "smoothened signalling pathway" EXACT [] xref: GO:0007224 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001765 ! PTC1_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN relationship: has_participant CCO:B0015164 ! HHIP_HUMAN relationship: has_participant CCO:B0054965 ! GLI2_HUMAN relationship: has_participant CCO:B0055873 ! IFT88_HUMAN relationship: has_participant CCO:B0055978 ! FKBP8_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0059332 ! IFT52_HUMAN [Term] id: CCO:P0000759 name: patched ligand processing namespace: biological_process def: "The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol moieties." [PMID:15057936] synonym: "Hedgehog protein processing" NARROW [] xref: GO:0007225 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000758 ! smoothened signaling pathway [Term] id: CCO:P0000760 name: signal transduction downstream of smoothened namespace: biological_process def: "The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway." [PMID:15057936] xref: GO:0007227 is_a: CCO:P0000708 ! signal transduction relationship: part_of CCO:P0000758 ! smoothened signaling pathway [Term] id: CCO:P0000761 name: positive regulation of hh target transcription factor activity namespace: biological_process def: "Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited." [GOC:dph, GOC:tb, PMID:11912487, PMID:15057936] synonym: "activation of hh target transcription factor" EXACT [GOC:dph, GOC:tb] xref: GO:0007228 is_a: CCO:P0003022 ! positive regulation of transcription factor activity relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: part_of CCO:P0000760 ! signal transduction downstream of smoothened [Term] id: CCO:P0000762 name: integrin-mediated signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of an integrin binding to one of its physiological ligands." [GOC:mah] synonym: "integrin-mediated signalling pathway" EXACT [] xref: GO:0007229 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001782 ! CASL_HUMAN relationship: has_participant CCO:B0002059 ! LAP2_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN relationship: has_participant CCO:B0005812 ! FAK1_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0006318 ! ITAE_HUMAN relationship: has_participant CCO:B0017433 ! BPA1_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0019660 ! Q59FG3_HUMAN relationship: has_participant CCO:B0019689 ! ATS1_HUMAN relationship: has_participant CCO:B0019703 ! Q59FE5_HUMAN relationship: has_participant CCO:B0021696 ! CTGF_HUMAN relationship: has_participant CCO:B0024051 ! ADEC1_HUMAN relationship: has_participant CCO:B0026210 ! Q59FA8_HUMAN relationship: has_participant CCO:B0026213 ! ITA8_HUMAN relationship: has_participant CCO:B0026215 ! ITA2B_HUMAN relationship: has_participant CCO:B0026216 ! Q17R67_HUMAN relationship: has_participant CCO:B0026217 ! ITA5_HUMAN relationship: has_participant CCO:B0026218 ! ITAV_HUMAN relationship: has_participant CCO:B0029727 ! CEAM1_HUMAN relationship: has_participant CCO:B0033110 ! Q16157_HUMAN relationship: has_participant CCO:B0033114 ! ITB4_HUMAN relationship: has_participant CCO:B0033120 ! ITB5_HUMAN relationship: has_participant CCO:B0033122 ! ITB2_HUMAN relationship: has_participant CCO:B0033125 ! ITB8_HUMAN relationship: has_participant CCO:B0033128 ! Q59FN1_HUMAN relationship: has_participant CCO:B0033131 ! Q5T3E5_HUMAN relationship: has_participant CCO:B0033132 ! Q59H50_HUMAN relationship: has_participant CCO:B0033133 ! ITB6_HUMAN relationship: has_participant CCO:B0033134 ! A8MYE6_HUMAN relationship: has_participant CCO:B0033136 ! Q8WUM6_HUMAN relationship: has_participant CCO:B0033137 ! ITB7_HUMAN relationship: has_participant CCO:B0033138 ! ITB1_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN relationship: has_participant CCO:B0033143 ! Q5T3E4_HUMAN relationship: has_participant CCO:B0038563 ! ADA11_HUMAN relationship: has_participant CCO:B0049000 ! Q59EX1_HUMAN relationship: has_participant CCO:B0050187 ! Q8N882_HUMAN relationship: has_participant CCO:B0050188 ! Q4VAK1_HUMAN relationship: has_participant CCO:B0050189 ! ITAM_HUMAN relationship: has_participant CCO:B0050190 ! ITAD_HUMAN relationship: has_participant CCO:B0050191 ! ITA11_HUMAN relationship: has_participant CCO:B0050192 ! ITAX_HUMAN relationship: has_participant CCO:B0050193 ! Q59H14_HUMAN relationship: has_participant CCO:B0050195 ! Q8TES5_HUMAN relationship: has_participant CCO:B0050196 ! ITA2_HUMAN relationship: has_participant CCO:B0050197 ! A8MPT3_HUMAN relationship: has_participant CCO:B0050198 ! A8MTX2_HUMAN relationship: has_participant CCO:B0050199 ! Q96HB1_HUMAN relationship: has_participant CCO:B0050200 ! A8MZ95_HUMAN relationship: has_participant CCO:B0050202 ! ITAL_HUMAN relationship: has_participant CCO:B0053990 ! A8MPU2_HUMAN relationship: has_participant CCO:B0054350 ! O14549_HUMAN relationship: has_participant CCO:B0054364 ! ADA10_HUMAN relationship: has_participant CCO:B0054492 ! LAT_HUMAN relationship: has_participant CCO:B0054652 ! ITA10_HUMAN relationship: has_participant CCO:B0054809 ! ITGBL_HUMAN relationship: has_participant CCO:B0054859 ! CO3A1_HUMAN relationship: has_participant CCO:B0055015 ! ITA4_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN relationship: has_participant CCO:B0055154 ! ITA6_HUMAN relationship: has_participant CCO:B0055189 ! ITA3_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0055541 ! ITA1_HUMAN relationship: has_participant CCO:B0055752 ! Q05BT6_HUMAN relationship: has_participant CCO:B0055782 ! COGA1_HUMAN relationship: has_participant CCO:B0055793 ! CD47_HUMAN relationship: has_participant CCO:B0055907 ! ILK_HUMAN relationship: has_participant CCO:B0055939 ! ITA7_HUMAN relationship: has_participant CCO:B0055943 ! ITA9_HUMAN relationship: has_participant CCO:B0056384 ! Q59F03_HUMAN relationship: has_participant CCO:B0056393 ! Q59FP4_HUMAN relationship: has_participant CCO:B0056829 ! Q6ISP1_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0057108 ! ATS13_HUMAN relationship: has_participant CCO:B0057164 ! Q7Z4J1_HUMAN relationship: has_participant CCO:B0057210 ! Q7Z7E1_HUMAN relationship: has_participant CCO:B0057211 ! Q7Z7E3_HUMAN relationship: has_participant CCO:B0057212 ! Q7Z7E5_HUMAN relationship: has_participant CCO:B0058353 ! PRAM_HUMAN relationship: has_participant CCO:B0058509 ! CCM2_HUMAN relationship: has_participant CCO:B0059377 ! ANGL3_HUMAN [Term] id: CCO:P0000763 name: osmosensory signaling pathway namespace: biological_process def: "The series of molecular signals initiated in response to osmotic change." [GOC:jl] subset: gosubset_prok synonym: "osmolarity sensing" EXACT [] synonym: "osmolarity sensing signaling pathway" EXACT [] synonym: "osmolarity sensing signalling pathway" EXACT [] synonym: "osmosensory signalling pathway" EXACT [] synonym: "signal transduction during osmotic stress" EXACT [] xref: GO:0007231 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0038926 ! TRPV4_HUMAN [Term] id: CCO:P0000764 name: osmosensory signaling pathway via Sho1 osmosensor namespace: biological_process def: "A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system." [GOC:jl] synonym: "osmosensory signalling pathway via Sho1 osmosensor" EXACT [] synonym: "signal transduction during osmotic stress via Sho1 osmosensor" EXACT [] xref: GO:0007232 is_a: CCO:P0000763 ! osmosensory signaling pathway [Term] id: CCO:P0000765 name: osmosensory signaling pathway via two-component system namespace: biological_process def: "A series of molecular signals generated in response to osmotic change, as mediated through a two-component (phosphorelay) system." [PMID:9843501] subset: gosubset_prok synonym: "osmolarity sensing via two-component system" EXACT [] synonym: "osmolarity signaling pathway via two-component system" EXACT [] synonym: "osmolarity signalling pathway via two-component system" EXACT [] synonym: "osmosensory signalling pathway via two-component system" EXACT [] synonym: "signal transduction during osmotic stress via two-component system" EXACT [] xref: GO:0007234 is_a: CCO:P0000763 ! osmosensory signaling pathway relationship: part_of CCO:P0000401 ! two-component signal transduction system (phosphorelay) [Term] id: CCO:P0000766 name: intracellular signaling cascade namespace: biological_process def: "A series of reactions within the cell that occur as a result of a single trigger reaction or compound." [GOC:jl, http://cancerweb.ncl.ac.uk/] subset: gosubset_prok synonym: "intracellular signalling cascade" EXACT [] xref: GO:0007242 is_a: CCO:P0000708 ! signal transduction relationship: has_participant CCO:B0001356 ! CTRO_HUMAN relationship: has_participant CCO:B0001369 ! MK13_HUMAN relationship: has_participant CCO:B0001406 ! ADCY3_HUMAN relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001504 ! IL8_HUMAN relationship: has_participant CCO:B0001528 ! STMN1_HUMAN relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001566 ! DUS1_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001665 ! MK12_HUMAN relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0001939 ! TLK2_HUMAN relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0002008 ! RASF5_HUMAN relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0002039 ! SIPA1_HUMAN relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN relationship: has_participant CCO:B0002151 ! PLCB1_HUMAN relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0002220 ! TLK1_HUMAN relationship: has_participant CCO:B0005173 ! KPCI_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005273 ! TOLIP_HUMAN relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0005315 ! KPCZ_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005488 ! 1433E_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005608 ! PTN6_HUMAN relationship: has_participant CCO:B0005610 ! PLCG1_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005708 ! ARAF_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0005892 ! MK11_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0005913 ! BRAF1_HUMAN relationship: has_participant CCO:B0005923 ! BMX_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0006073 ! AN32A_HUMAN relationship: has_participant CCO:B0006123 ! BCR_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN relationship: has_participant CCO:B0006233 ! PDPK1_HUMAN relationship: has_participant CCO:B0015270 ! DFFB_HUMAN relationship: has_participant CCO:B0015783 ! Q5T188_HUMAN relationship: has_participant CCO:B0015787 ! Q5T182_HUMAN relationship: has_participant CCO:B0015789 ! Q5T187_HUMAN relationship: has_participant CCO:B0015792 ! Q5T181_HUMAN relationship: has_participant CCO:B0016679 ! A6NJF2_HUMAN relationship: has_participant CCO:B0016680 ! ANPRA_HUMAN relationship: has_participant CCO:B0016681 ! ANPRB_HUMAN relationship: has_participant CCO:B0016682 ! GUC2D_HUMAN relationship: has_participant CCO:B0016684 ! GUC2F_HUMAN relationship: has_participant CCO:B0016685 ! GUC2C_HUMAN relationship: has_participant CCO:B0016816 ! APBA3_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN relationship: has_participant CCO:B0017622 ! 3BP5_HUMAN relationship: has_participant CCO:B0018804 ! Q5T3Y5_HUMAN relationship: has_participant CCO:B0018806 ! DCDC2_HUMAN relationship: has_participant CCO:B0018807 ! DCD2B_HUMAN relationship: has_participant CCO:B0018931 ! Q9P235_HUMAN relationship: has_participant CCO:B0019541 ! TMPS6_HUMAN relationship: has_participant CCO:B0020873 ! Q6ZTM6_HUMAN relationship: has_participant CCO:B0020874 ! ADCY2_HUMAN relationship: has_participant CCO:B0020879 ! ADCY7_HUMAN relationship: has_participant CCO:B0020880 ! ADCY4_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0021340 ! CHSP1_HUMAN relationship: has_participant CCO:B0021696 ! CTGF_HUMAN relationship: has_participant CCO:B0022454 ! KAP3_HUMAN relationship: has_participant CCO:B0022455 ! KAP2_HUMAN relationship: has_participant CCO:B0023033 ! A2A2D2_HUMAN relationship: has_participant CCO:B0023034 ! STMN2_HUMAN relationship: has_participant CCO:B0023035 ! A2A2D0_HUMAN relationship: has_participant CCO:B0023036 ! Q59G27_HUMAN relationship: has_participant CCO:B0023038 ! STMN4_HUMAN relationship: has_participant CCO:B0023039 ! STMN3_HUMAN relationship: has_participant CCO:B0024481 ! Q6ZNQ9_HUMAN relationship: has_participant CCO:B0024484 ! PLCB3_HUMAN relationship: has_participant CCO:B0024486 ! Q8N1A4_HUMAN relationship: has_participant CCO:B0024696 ! BIG2_HUMAN relationship: has_participant CCO:B0025044 ! KPCG_HUMAN relationship: has_participant CCO:B0025045 ! KPCB_HUMAN relationship: has_participant CCO:B0025046 ! KPCL_HUMAN relationship: has_participant CCO:B0025049 ! A6PVX6_HUMAN relationship: has_participant CCO:B0025051 ! Q5JUN8_HUMAN relationship: has_participant CCO:B0025052 ! Q7Z727_HUMAN relationship: has_participant CCO:B0025053 ! KPCT_HUMAN relationship: has_participant CCO:B0025054 ! KPCE_HUMAN relationship: has_participant CCO:B0025112 ! COR2A_HUMAN relationship: has_participant CCO:B0025814 ! RAC3_HUMAN relationship: has_participant CCO:B0026418 ! NUDT4_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0026617 ! A8K6J2_HUMAN relationship: has_participant CCO:B0026618 ! Q5JYS9_HUMAN relationship: has_participant CCO:B0027936 ! Q14BD4_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN relationship: has_participant CCO:B0028634 ! KS6A2_HUMAN relationship: has_participant CCO:B0028938 ! EFS_HUMAN relationship: has_participant CCO:B0029125 ! Q2M5E1_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN relationship: has_participant CCO:B0029425 ! Q5JY90_HUMAN relationship: has_participant CCO:B0030607 ! Q5VZY9_HUMAN relationship: has_participant CCO:B0030613 ! DCLK1_HUMAN relationship: has_participant CCO:B0030615 ! DCX_HUMAN relationship: has_participant CCO:B0030617 ! DCLK2_HUMAN relationship: has_participant CCO:B0030618 ! Q4W5L5_HUMAN relationship: has_participant CCO:B0031117 ! Q4LE74_HUMAN relationship: has_participant CCO:B0031122 ! MYO9B_HUMAN relationship: has_participant CCO:B0033903 ! CENB1_HUMAN relationship: has_participant CCO:B0037015 ! Q1ZYL3_HUMAN relationship: has_participant CCO:B0037017 ! ARHG4_HUMAN relationship: has_participant CCO:B0037018 ! PREX2_HUMAN relationship: has_participant CCO:B0037020 ! DEPD6_HUMAN relationship: has_participant CCO:B0037021 ! PREX1_HUMAN relationship: has_participant CCO:B0038385 ! RPGF1_HUMAN relationship: has_participant CCO:B0040141 ! B0I1T6_HUMAN relationship: has_participant CCO:B0041668 ! GROA_HUMAN relationship: has_participant CCO:B0042773 ! B0ZBF1_HUMAN relationship: has_participant CCO:B0043529 ! SPSB3_HUMAN relationship: has_participant CCO:B0043530 ! Q96LS6_HUMAN relationship: has_participant CCO:B0043605 ! DEDD2_HUMAN relationship: has_participant CCO:B0043706 ! SPSB4_HUMAN relationship: has_participant CCO:B0043707 ! SPSB2_HUMAN relationship: has_participant CCO:B0043708 ! SPSB1_HUMAN relationship: has_participant CCO:B0050358 ! MLL3_HUMAN relationship: has_participant CCO:B0053700 ! A0JLP1_HUMAN relationship: has_participant CCO:B0053714 ! A2A284_HUMAN relationship: has_participant CCO:B0053762 ! A4FU15_HUMAN relationship: has_participant CCO:B0053852 ! A6NHV0_HUMAN relationship: has_participant CCO:B0053869 ! A6NJ96_HUMAN relationship: has_participant CCO:B0053879 ! A6NK59_HUMAN relationship: has_participant CCO:B0053882 ! A6NKC6_HUMAN relationship: has_participant CCO:B0053884 ! A6NKG8_HUMAN relationship: has_participant CCO:B0053885 ! A6NKJ3_HUMAN relationship: has_participant CCO:B0053897 ! A6NLH6_HUMAN relationship: has_participant CCO:B0053962 ! A8K3C0_HUMAN relationship: has_participant CCO:B0053977 ! A8K7K1_HUMAN relationship: has_participant CCO:B0053978 ! A8K8D4_HUMAN relationship: has_participant CCO:B0053991 ! A8MPW5_HUMAN relationship: has_participant CCO:B0053994 ! A8MQ12_HUMAN relationship: has_participant CCO:B0054000 ! A8MQU9_HUMAN relationship: has_participant CCO:B0054007 ! A8MSJ7_HUMAN relationship: has_participant CCO:B0054036 ! A8MU01_HUMAN relationship: has_participant CCO:B0054062 ! A8MVN0_HUMAN relationship: has_participant CCO:B0054067 ! A8MVW4_HUMAN relationship: has_participant CCO:B0054103 ! A8MXU2_HUMAN relationship: has_participant CCO:B0054118 ! A8MY87_HUMAN relationship: has_participant CCO:B0054127 ! A8MYR5_HUMAN relationship: has_participant CCO:B0054132 ! DCDCX_HUMAN relationship: has_participant CCO:B0054163 ! B0KZ81_HUMAN relationship: has_participant CCO:B0054164 ! B0LPH5_HUMAN relationship: has_participant CCO:B0054197 ! B0YJ91_HUMAN relationship: has_participant CCO:B0054208 ! B1AH81_HUMAN relationship: has_participant CCO:B0054250 ! B1AM27_HUMAN relationship: has_participant CCO:B0054267 ! B1AP22_HUMAN relationship: has_participant CCO:B0054307 ! DFFA_HUMAN relationship: has_participant CCO:B0054332 ! SDCB1_HUMAN relationship: has_participant CCO:B0054343 ! SH2B2_HUMAN relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0054347 ! SOCS7_HUMAN relationship: has_participant CCO:B0054349 ! SOCS6_HUMAN relationship: has_participant CCO:B0054363 ! DVL1_HUMAN relationship: has_participant CCO:B0054377 ! UN13B_HUMAN relationship: has_participant CCO:B0054403 ! MCF2L_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054451 ! PLXB1_HUMAN relationship: has_participant CCO:B0054469 ! ADCY6_HUMAN relationship: has_participant CCO:B0054478 ! RASL2_HUMAN relationship: has_participant CCO:B0054492 ! LAT_HUMAN relationship: has_participant CCO:B0054511 ! AKA7A_HUMAN relationship: has_participant CCO:B0054515 ! CIKS_HUMAN relationship: has_participant CCO:B0054530 ! TYOBP_HUMAN relationship: has_participant CCO:B0054534 ! KALRN_HUMAN relationship: has_participant CCO:B0054563 ! ADCY9_HUMAN relationship: has_participant CCO:B0054596 ! PLCH2_HUMAN relationship: has_participant CCO:B0054597 ! O75039_HUMAN relationship: has_participant CCO:B0054602 ! ROCK2_HUMAN relationship: has_participant CCO:B0054604 ! DEPD5_HUMAN relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN relationship: has_participant CCO:B0054619 ! GCYB2_HUMAN relationship: has_participant CCO:B0054677 ! DGKI_HUMAN relationship: has_participant CCO:B0054678 ! RGS9_HUMAN relationship: has_participant CCO:B0054699 ! KPCD3_HUMAN relationship: has_participant CCO:B0054700 ! RGS11_HUMAN relationship: has_participant CCO:B0054743 ! GRP1_HUMAN relationship: has_participant CCO:B0054747 ! RASL1_HUMAN relationship: has_participant CCO:B0054757 ! RPGF3_HUMAN relationship: has_participant CCO:B0054759 ! CNIH_HUMAN relationship: has_participant CCO:B0054773 ! ADCY5_HUMAN relationship: has_participant CCO:B0054779 ! NFAC1_HUMAN relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0054892 ! NTRK1_HUMAN relationship: has_participant CCO:B0054927 ! PLEK_HUMAN relationship: has_participant CCO:B0054953 ! RB40L_HUMAN relationship: has_participant CCO:B0054981 ! MCF2_HUMAN relationship: has_participant CCO:B0054988 ! RALA_HUMAN relationship: has_participant CCO:B0054989 ! RALB_HUMAN relationship: has_participant CCO:B0055014 ! SCG2_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN relationship: has_participant CCO:B0055044 ! CHIN_HUMAN relationship: has_participant CCO:B0055057 ! FER_HUMAN relationship: has_participant CCO:B0055061 ! PLCG2_HUMAN relationship: has_participant CCO:B0055155 ! S10A1_HUMAN relationship: has_participant CCO:B0055162 ! DGKA_HUMAN relationship: has_participant CCO:B0055267 ! GCYA2_HUMAN relationship: has_participant CCO:B0055268 ! CD80_HUMAN relationship: has_participant CCO:B0055325 ! ADCY8_HUMAN relationship: has_participant CCO:B0055353 ! TEC_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0055376 ! CRK_HUMAN relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN relationship: has_participant CCO:B0055425 ! DGKG_HUMAN relationship: has_participant CCO:B0055433 ! RGS6_HUMAN relationship: has_participant CCO:B0055438 ! RGS7_HUMAN relationship: has_participant CCO:B0055439 ! PSN2_HUMAN relationship: has_participant CCO:B0055462 ! PLCD1_HUMAN relationship: has_participant CCO:B0055485 ! DGKE_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN relationship: has_participant CCO:B0055500 ! CHIO_HUMAN relationship: has_participant CCO:B0055503 ! DGKQ_HUMAN relationship: has_participant CCO:B0055516 ! DVL1L_HUMAN relationship: has_participant CCO:B0055552 ! RP1_HUMAN relationship: has_participant CCO:B0055591 ! DCDC1_HUMAN relationship: has_participant CCO:B0055667 ! SHC2_HUMAN relationship: has_participant CCO:B0055705 ! GCYA3_HUMAN relationship: has_participant CCO:B0055706 ! GCYB1_HUMAN relationship: has_participant CCO:B0055745 ! KPCD_HUMAN relationship: has_participant CCO:B0055794 ! ADCY1_HUMAN relationship: has_participant CCO:B0055796 ! ITK_HUMAN relationship: has_participant CCO:B0055800 ! Q08AQ7_HUMAN relationship: has_participant CCO:B0055801 ! Q08AR7_HUMAN relationship: has_participant CCO:B0055802 ! Q08AR8_HUMAN relationship: has_participant CCO:B0055818 ! PLCX2_HUMAN relationship: has_participant CCO:B0055843 ! AKP13_HUMAN relationship: has_participant CCO:B0055845 ! RB40B_HUMAN relationship: has_participant CCO:B0055849 ! Q12843_HUMAN relationship: has_participant CCO:B0055861 ! ABR_HUMAN relationship: has_participant CCO:B0055865 ! TIAM1_HUMAN relationship: has_participant CCO:B0055910 ! ROCK1_HUMAN relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN relationship: has_participant CCO:B0055922 ! Q13518_HUMAN relationship: has_participant CCO:B0055932 ! DGKZ_HUMAN relationship: has_participant CCO:B0055953 ! CAYP1_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: has_participant CCO:B0055978 ! FKBP8_HUMAN relationship: has_participant CCO:B0056008 ! RASA3_HUMAN relationship: has_participant CCO:B0056034 ! Q14DU5_HUMAN relationship: has_participant CCO:B0056044 ! PLCL1_HUMAN relationship: has_participant CCO:B0056047 ! PLCB4_HUMAN relationship: has_participant CCO:B0056052 ! RASA2_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056166 ! MAPK3_HUMAN relationship: has_participant CCO:B0056176 ! DGKD_HUMAN relationship: has_participant CCO:B0056190 ! Q1KKQ2_HUMAN relationship: has_participant CCO:B0056204 ! Q2M1H4_HUMAN relationship: has_participant CCO:B0056225 ! Q2TAI4_HUMAN relationship: has_participant CCO:B0056283 ! Q3ZCN8_HUMAN relationship: has_participant CCO:B0056303 ! Q49AA3_HUMAN relationship: has_participant CCO:B0056310 ! Q4F7X0_HUMAN relationship: has_participant CCO:B0056320 ! PLCH1_HUMAN relationship: has_participant CCO:B0056323 ! Q4TT72_HUMAN relationship: has_participant CCO:B0056343 ! RHG29_HUMAN relationship: has_participant CCO:B0056367 ! Q53TN0_HUMAN relationship: has_participant CCO:B0056372 ! Q569L6_HUMAN relationship: has_participant CCO:B0056381 ! Q59EM3_HUMAN relationship: has_participant CCO:B0056386 ! Q59F39_HUMAN relationship: has_participant CCO:B0056388 ! Q59F62_HUMAN relationship: has_participant CCO:B0056400 ! Q59G99_HUMAN relationship: has_participant CCO:B0056403 ! Q59GE2_HUMAN relationship: has_participant CCO:B0056404 ! Q59GE8_HUMAN relationship: has_participant CCO:B0056414 ! Q59GZ2_HUMAN relationship: has_participant CCO:B0056428 ! Q5FWG1_HUMAN relationship: has_participant CCO:B0056437 ! Q5H9B2_HUMAN relationship: has_participant CCO:B0056443 ! Q5HYD7_HUMAN relationship: has_participant CCO:B0056506 ! Q5JYJ2_HUMAN relationship: has_participant CCO:B0056507 ! Q5JYJ3_HUMAN relationship: has_participant CCO:B0056508 ! Q5JYJ5_HUMAN relationship: has_participant CCO:B0056509 ! Q5JYJ6_HUMAN relationship: has_participant CCO:B0056510 ! Q5JYJ7_HUMAN relationship: has_participant CCO:B0056511 ! Q5JYT3_HUMAN relationship: has_participant CCO:B0056514 ! Q5JYZ5_HUMAN relationship: has_participant CCO:B0056515 ! DGKK_HUMAN relationship: has_participant CCO:B0056533 ! Q5SQI6_HUMAN relationship: has_participant CCO:B0056552 ! Q5SYV3_HUMAN relationship: has_participant CCO:B0056568 ! Q5T3H4_HUMAN relationship: has_participant CCO:B0056593 ! Q5T7A0_HUMAN relationship: has_participant CCO:B0056604 ! DEP1A_HUMAN relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN relationship: has_participant CCO:B0056664 ! Q5VWL4_HUMAN relationship: has_participant CCO:B0056668 ! Q5VY92_HUMAN relationship: has_participant CCO:B0056669 ! Q5VY93_HUMAN relationship: has_participant CCO:B0056688 ! PLCX3_HUMAN relationship: has_participant CCO:B0056690 ! TENC1_HUMAN relationship: has_participant CCO:B0056701 ! Q68D02_HUMAN relationship: has_participant CCO:B0056713 ! PKHM4_HUMAN relationship: has_participant CCO:B0056729 ! MRCKG_HUMAN relationship: has_participant CCO:B0056861 ! Q6NUQ6_HUMAN relationship: has_participant CCO:B0056908 ! CNIH2_HUMAN relationship: has_participant CCO:B0056933 ! Q6QME9_HUMAN relationship: has_participant CCO:B0056938 ! SHC4_HUMAN relationship: has_participant CCO:B0056960 ! KSR2_HUMAN relationship: has_participant CCO:B0056974 ! DNMBP_HUMAN relationship: has_participant CCO:B0056976 ! Q6ZMJ1_HUMAN relationship: has_participant CCO:B0056987 ! Q6ZMP3_HUMAN relationship: has_participant CCO:B0056992 ! STAC2_HUMAN relationship: has_participant CCO:B0057011 ! DEFI8_HUMAN relationship: has_participant CCO:B0057041 ! DCDC5_HUMAN relationship: has_participant CCO:B0057046 ! Q6ZS32_HUMAN relationship: has_participant CCO:B0057059 ! Q6ZSX2_HUMAN relationship: has_participant CCO:B0057063 ! Q6ZT25_HUMAN relationship: has_participant CCO:B0057065 ! Q6ZT60_HUMAN relationship: has_participant CCO:B0057075 ! Q6ZUK8_HUMAN relationship: has_participant CCO:B0057076 ! Q6ZUL6_HUMAN relationship: has_participant CCO:B0057087 ! ASB18_HUMAN relationship: has_participant CCO:B0057090 ! PKHM3_HUMAN relationship: has_participant CCO:B0057123 ! GRP2_HUMAN relationship: has_participant CCO:B0057149 ! GP155_HUMAN relationship: has_participant CCO:B0057192 ! Q7Z670_HUMAN relationship: has_participant CCO:B0057213 ! MIST_HUMAN relationship: has_participant CCO:B0057236 ! KAISO_HUMAN relationship: has_participant CCO:B0057238 ! Q86TH3_HUMAN relationship: has_participant CCO:B0057242 ! Q86TY6_HUMAN relationship: has_participant CCO:B0057290 ! Q86XJ6_HUMAN relationship: has_participant CCO:B0057292 ! DGKH_HUMAN relationship: has_participant CCO:B0057314 ! PLCZ1_HUMAN relationship: has_participant CCO:B0057328 ! Q8IUU5_HUMAN relationship: has_participant CCO:B0057331 ! Q8IUY2_HUMAN relationship: has_participant CCO:B0057337 ! GRP3_HUMAN relationship: has_participant CCO:B0057343 ! TIAM2_HUMAN relationship: has_participant CCO:B0057348 ! KSR1_HUMAN relationship: has_participant CCO:B0057350 ! Q8IVW9_HUMAN relationship: has_participant CCO:B0057359 ! Q8IWC5_HUMAN relationship: has_participant CCO:B0057362 ! RP1L1_HUMAN relationship: has_participant CCO:B0057364 ! LAX1_HUMAN relationship: has_participant CCO:B0057433 ! RGNEF_HUMAN relationship: has_participant CCO:B0057441 ! DEPD4_HUMAN relationship: has_participant CCO:B0057455 ! PLCD3_HUMAN relationship: has_participant CCO:B0057472 ! Q8N5H0_HUMAN relationship: has_participant CCO:B0057507 ! Q8N7S5_HUMAN relationship: has_participant CCO:B0057509 ! Q8N7X7_HUMAN relationship: has_participant CCO:B0057518 ! Q8N8F5_HUMAN relationship: has_participant CCO:B0057556 ! UN13C_HUMAN relationship: has_participant CCO:B0057569 ! Q8NCK8_HUMAN relationship: has_participant CCO:B0057592 ! PDZD8_HUMAN relationship: has_participant CCO:B0057595 ! NFAM1_HUMAN relationship: has_participant CCO:B0057881 ! INADL_HUMAN relationship: has_participant CCO:B0057902 ! CNIH3_HUMAN relationship: has_participant CCO:B0057905 ! Q8TBM4_HUMAN relationship: has_participant CCO:B0057924 ! Q8TDA3_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: has_participant CCO:B0057975 ! FRS2_HUMAN relationship: has_participant CCO:B0057981 ! Q8WUM3_HUMAN relationship: has_participant CCO:B0057986 ! DEP1B_HUMAN relationship: has_participant CCO:B0057988 ! BLNK_HUMAN relationship: has_participant CCO:B0058007 ! ASB5_HUMAN relationship: has_participant CCO:B0058019 ! ASB11_HUMAN relationship: has_participant CCO:B0058020 ! SOCS4_HUMAN relationship: has_participant CCO:B0058021 ! RB40A_HUMAN relationship: has_participant CCO:B0058023 ! ASB10_HUMAN relationship: has_participant CCO:B0058024 ! ACO11_HUMAN relationship: has_participant CCO:B0058026 ! ASB17_HUMAN relationship: has_participant CCO:B0058027 ! ASB15_HUMAN relationship: has_participant CCO:B0058028 ! DYH12_HUMAN relationship: has_participant CCO:B0058029 ! ASB13_HUMAN relationship: has_participant CCO:B0058030 ! ASB12_HUMAN relationship: has_participant CCO:B0058055 ! RPGF4_HUMAN relationship: has_participant CCO:B0058060 ! SHC3_HUMAN relationship: has_participant CCO:B0058075 ! HMHA1_HUMAN relationship: has_participant CCO:B0058113 ! Q92942_HUMAN relationship: has_participant CCO:B0058118 ! DVL3_HUMAN relationship: has_participant CCO:B0058199 ! ASB9_HUMAN relationship: has_participant CCO:B0058228 ! Q96II5_HUMAN relationship: has_participant CCO:B0058288 ! STAC3_HUMAN relationship: has_participant CCO:B0058312 ! ASB16_HUMAN relationship: has_participant CCO:B0058339 ! ADCYA_HUMAN relationship: has_participant CCO:B0058349 ! ASB2_HUMAN relationship: has_participant CCO:B0058352 ! DEPD7_HUMAN relationship: has_participant CCO:B0058384 ! RB40C_HUMAN relationship: has_participant CCO:B0058415 ! STAC_HUMAN relationship: has_participant CCO:B0058484 ! NEUL2_HUMAN relationship: has_participant CCO:B0058489 ! PLCD4_HUMAN relationship: has_participant CCO:B0058574 ! GNB1L_HUMAN relationship: has_participant CCO:B0058575 ! Q9BYD4_HUMAN relationship: has_participant CCO:B0058604 ! KPCD2_HUMAN relationship: has_participant CCO:B0058644 ! NTAL_HUMAN relationship: has_participant CCO:B0058647 ! Q9H023_HUMAN relationship: has_participant CCO:B0058662 ! SDCB2_HUMAN relationship: has_participant CCO:B0058691 ! CLC4M_HUMAN relationship: has_participant CCO:B0058734 ! ASB7_HUMAN relationship: has_participant CCO:B0058738 ! ASB8_HUMAN relationship: has_participant CCO:B0058795 ! NOD2_HUMAN relationship: has_participant CCO:B0058829 ! CD209_HUMAN relationship: has_participant CCO:B0058842 ! TREM1_HUMAN relationship: has_participant CCO:B0058899 ! SH2B1_HUMAN relationship: has_participant CCO:B0058900 ! TULP4_HUMAN relationship: has_participant CCO:B0058919 ! CISH_HUMAN relationship: has_participant CCO:B0058927 ! PLCX1_HUMAN relationship: has_participant CCO:B0058939 ! PAG1_HUMAN relationship: has_participant CCO:B0058943 ! ASB6_HUMAN relationship: has_participant CCO:B0058971 ! WSB2_HUMAN relationship: has_participant CCO:B0058972 ! PLEK2_HUMAN relationship: has_participant CCO:B0059024 ! CNIH4_HUMAN relationship: has_participant CCO:B0059036 ! GMIP_HUMAN relationship: has_participant CCO:B0059045 ! SIRPG_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059118 ! Q9UFY1_HUMAN relationship: has_participant CCO:B0059119 ! Q9UG07_HUMAN relationship: has_participant CCO:B0059207 ! VAV3_HUMAN relationship: has_participant CCO:B0059224 ! ARMS_HUMAN relationship: has_participant CCO:B0059252 ! Q9UNJ2_HUMAN relationship: has_participant CCO:B0059258 ! PA24C_HUMAN relationship: has_participant CCO:B0059265 ! PLCL2_HUMAN relationship: has_participant CCO:B0059271 ! UN13A_HUMAN relationship: has_participant CCO:B0059272 ! SHAN2_HUMAN relationship: has_participant CCO:B0059283 ! SH2B3_HUMAN relationship: has_participant CCO:B0059290 ! NOD1_HUMAN relationship: has_participant CCO:B0059299 ! T53G5_HUMAN relationship: has_participant CCO:B0059307 ! FYV1_HUMAN relationship: has_participant CCO:B0059343 ! GRIP1_HUMAN relationship: has_participant CCO:B0059361 ! PKHM1_HUMAN relationship: has_participant CCO:B0059362 ! RPGF2_HUMAN relationship: has_participant CCO:B0059371 ! ASB4_HUMAN relationship: has_participant CCO:B0059372 ! ASB3_HUMAN relationship: has_participant CCO:B0059373 ! ASB1_HUMAN relationship: has_participant CCO:B0059385 ! MRCKB_HUMAN relationship: has_participant CCO:B0059398 ! Q9Y656_HUMAN relationship: has_participant CCO:B0059406 ! WSB1_HUMAN relationship: has_participant CCO:B0059409 ! STYL1_HUMAN relationship: has_participant CCO:B0059417 ! DGKB_HUMAN [Term] id: CCO:P0000767 name: protein kinase cascade namespace: biological_process def: "A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound." [GOC:jl, http://cancerweb.ncl.ac.uk/] xref: GO:0007243 xref: Reactome:163358 xref: Reactome:211745 xref: Reactome:221512 xref: Reactome:230132 xref: Reactome:238158 xref: Reactome:244747 xref: Reactome:249654 xref: Reactome:252437 xref: Reactome:255603 xref: Reactome:258983 xref: Reactome:262353 xref: Reactome:265200 xref: Reactome:268322 xref: Reactome:274021 xref: Reactome:280499 xref: Reactome:282794 xref: Reactome:286520 xref: Reactome:288299 xref: Reactome:291709 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0001369 ! MK13_HUMAN relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0001984 ! NEK11_HUMAN relationship: has_participant CCO:B0001999 ! HASP_HUMAN relationship: has_participant CCO:B0002061 ! SRPK1_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0005372 ! ADAM9_HUMAN relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0005629 ! KS6A4_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN relationship: has_participant CCO:B0005702 ! STK4_HUMAN relationship: has_participant CCO:B0005706 ! M4K2_HUMAN relationship: has_participant CCO:B0005873 ! SN1L2_HUMAN relationship: has_participant CCO:B0005892 ! MK11_HUMAN relationship: has_participant CCO:B0005934 ! WNK4_HUMAN relationship: has_participant CCO:B0006060 ! DAPK3_HUMAN relationship: has_participant CCO:B0006228 ! GLU2B_HUMAN relationship: has_participant CCO:B0015573 ! ST38L_HUMAN relationship: has_participant CCO:B0015584 ! STK38_HUMAN relationship: has_participant CCO:B0016331 ! AAKG3_HUMAN relationship: has_participant CCO:B0018166 ! ICK_HUMAN relationship: has_participant CCO:B0018532 ! KAPCG_HUMAN relationship: has_participant CCO:B0018534 ! KAPCB_HUMAN relationship: has_participant CCO:B0018543 ! KAPCA_HUMAN relationship: has_participant CCO:B0018778 ! M3K12_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0022813 ! SRPK2_HUMAN relationship: has_participant CCO:B0026499 ! TTP_HUMAN relationship: has_participant CCO:B0028618 ! KS6A3_HUMAN relationship: has_participant CCO:B0028620 ! KS6A6_HUMAN relationship: has_participant CCO:B0028627 ! KS6A1_HUMAN relationship: has_participant CCO:B0028634 ! KS6A2_HUMAN relationship: has_participant CCO:B0028635 ! A6NGG4_HUMAN relationship: has_participant CCO:B0033210 ! SGK2_HUMAN relationship: has_participant CCO:B0033471 ! F261_HUMAN relationship: has_participant CCO:B0036514 ! ST17A_HUMAN relationship: has_participant CCO:B0036523 ! ST17B_HUMAN relationship: has_participant CCO:B0036525 ! DAPK2_HUMAN relationship: has_participant CCO:B0036609 ! MAST1_HUMAN relationship: has_participant CCO:B0037391 ! MARK2_HUMAN relationship: has_participant CCO:B0037393 ! MARK1_HUMAN relationship: has_participant CCO:B0038258 ! ADA1A_HUMAN relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN relationship: has_participant CCO:B0041947 ! MINK1_HUMAN relationship: has_participant CCO:B0041953 ! M4K4_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0054370 ! ITBP1_HUMAN relationship: has_participant CCO:B0054407 ! FYB_HUMAN relationship: has_participant CCO:B0054589 ! NSMA_HUMAN relationship: has_participant CCO:B0054653 ! KS6A5_HUMAN relationship: has_participant CCO:B0054791 ! OXSR1_HUMAN relationship: has_participant CCO:B0054818 ! GSUB_HUMAN relationship: has_participant CCO:B0054883 ! PA21B_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0054977 ! KIT_HUMAN relationship: has_participant CCO:B0055353 ! TEC_HUMAN relationship: has_participant CCO:B0055364 ! ZAP70_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055554 ! NRG3_HUMAN relationship: has_participant CCO:B0055885 ! STK3_HUMAN relationship: has_participant CCO:B0057345 ! M4K3_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN relationship: has_participant CCO:B0058519 ! MKNK1_HUMAN relationship: has_participant CCO:B0058560 ! PINK1_HUMAN relationship: has_participant CCO:B0058581 ! WNK3_HUMAN relationship: has_participant CCO:B0058713 ! WNK1_HUMAN relationship: has_participant CCO:B0058786 ! MKNK2_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN relationship: has_participant CCO:B0059189 ! AKA11_HUMAN relationship: has_participant CCO:B0059344 ! WNK2_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN [Term] id: CCO:P0000768 name: I-kappaB kinase/NF-kappaB cascade namespace: biological_process def: "A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB, and is released when I-kappaB is phosphorylated by activated I-kappaB kinase." [GOC:jl, PMID:12773372] synonym: "activation of the inhibitor of kappa kinase" RELATED [] synonym: "NIK-I-kappaB/NF-kappaB cascade" EXACT [] xref: GO:0007249 xref: Reactome:166058 xref: Reactome:166166 xref: Reactome:211840 xref: Reactome:238238 is_a: CCO:P0000767 ! protein kinase cascade relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0005335 ! SNIP1_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005525 ! M3K1_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0022071 ! TLR4_HUMAN relationship: has_participant CCO:B0030165 ! TLR10_HUMAN relationship: has_participant CCO:B0030171 ! TLR2_HUMAN relationship: has_participant CCO:B0030172 ! TLR6_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN relationship: has_participant CCO:B0054457 ! IRAK2_HUMAN relationship: has_participant CCO:B0054761 ! TIAF1_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0055572 ! TIRAP_HUMAN relationship: has_participant CCO:B0056009 ! IRF3_HUMAN relationship: has_participant CCO:B0056658 ! IKBP1_HUMAN relationship: has_participant CCO:B0057124 ! NLRC3_HUMAN relationship: has_participant CCO:B0057293 ! TCAM2_HUMAN relationship: has_participant CCO:B0057321 ! TCAM1_HUMAN relationship: has_participant CCO:B0058009 ! EDAD_HUMAN relationship: has_participant CCO:B0058891 ! TLR9_HUMAN relationship: has_participant CCO:B0058892 ! TLR8_HUMAN relationship: has_participant CCO:B0058944 ! IRAK4_HUMAN relationship: has_participant CCO:B0058964 ! TLR7_HUMAN relationship: has_participant CCO:B0058969 ! KBRS2_HUMAN relationship: has_participant CCO:B0058970 ! KBRS1_HUMAN relationship: has_participant CCO:B0059026 ! PTAD1_HUMAN relationship: has_participant CCO:B0059423 ! LY96_HUMAN [Term] id: CCO:P0000769 name: activation of NF-kappaB-inducing kinase activity namespace: biological_process def: "The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues." [GOC:jl, PMID:12773372] synonym: "positive regulation of NF-kappaB-inducing kinase activity" EXACT [] xref: GO:0007250 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001448 ! TNF15_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0030172 ! TLR6_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0057563 ! Q8NC81_HUMAN relationship: has_participant CCO:B0058537 ! CAR10_HUMAN relationship: has_participant CCO:B0058558 ! CAR14_HUMAN relationship: has_participant CCO:B0059106 ! MALT1_HUMAN relationship: part_of CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:P0000770 name: I-kappaB phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into an I-kappaB protein." [GOC:jl] xref: GO:0007252 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005539 ! IKKA_HUMAN relationship: has_participant CCO:B0055882 ! PRDX4_HUMAN relationship: has_participant CCO:B0057322 ! RB6I2_HUMAN relationship: part_of CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:P0000771 name: cytoplasmic sequestering of NF-kappaB namespace: biological_process def: "The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus." [GOC:jl] synonym: "cytoplasmic NF-kappaB retention" EXACT [] synonym: "cytoplasmic NF-kappaB sequestration" EXACT [] synonym: "cytoplasmic NF-kappaB storage" EXACT [] synonym: "cytoplasmic retention of NF-kappaB" EXACT [] synonym: "cytoplasmic sequestration of NF-kappaB" EXACT [] synonym: "cytoplasmic storage of NF-kappaB" EXACT [] synonym: "maintenance of NF-kappaB location in cytoplasm" EXACT [GOC:dph, GOC:tb] xref: GO:0007253 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0028327 ! G3BP2_HUMAN relationship: has_participant CCO:B0055142 ! IL10_HUMAN relationship: has_participant CCO:B0059254 ! FAF1_HUMAN relationship: part_of CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:P0000772 name: JNK cascade namespace: biological_process def: "A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress." [GOC:bf, PMID:11790549] synonym: "SAPK cascade" BROAD [] synonym: "stress-activated protein kinase cascade" BROAD [] xref: GO:0007254 is_a: CCO:P0000403 ! MAPKKK cascade is_a: CCO:P0001379 ! stress-activated protein kinase signaling pathway relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001740 ! CSN1_HUMAN relationship: has_participant CCO:B0001746 ! GPS2_HUMAN relationship: has_participant CCO:B0001820 ! M3K11_HUMAN relationship: has_participant CCO:B0001995 ! RBCC1_HUMAN relationship: has_participant CCO:B0005603 ! TNIK_HUMAN relationship: has_participant CCO:B0005638 ! MK08_HUMAN relationship: has_participant CCO:B0005706 ! M4K2_HUMAN relationship: has_participant CCO:B0005915 ! M3K4_HUMAN relationship: has_participant CCO:B0006002 ! TRIB1_HUMAN relationship: has_participant CCO:B0018761 ! M3K13_HUMAN relationship: has_participant CCO:B0018770 ! M3K10_HUMAN relationship: has_participant CCO:B0018778 ! M3K12_HUMAN relationship: has_participant CCO:B0019510 ! TAOK3_HUMAN relationship: has_participant CCO:B0026768 ! MK10_HUMAN relationship: has_participant CCO:B0026769 ! MK09_HUMAN relationship: has_participant CCO:B0038116 ! MP2K4_HUMAN relationship: has_participant CCO:B0041947 ! MINK1_HUMAN relationship: has_participant CCO:B0055211 ! AA2BR_HUMAN relationship: has_participant CCO:B0055336 ! WNT5A_HUMAN relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0055700 ! ROR2_HUMAN relationship: has_participant CCO:B0056039 ! ARHG6_HUMAN relationship: has_participant CCO:B0056874 ! BORG3_HUMAN relationship: has_participant CCO:B0057345 ! M4K3_HUMAN relationship: has_participant CCO:B0057474 ! SH2D3_HUMAN relationship: has_participant CCO:B0057969 ! DUS19_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058464 ! DUS9_HUMAN relationship: has_participant CCO:B0058491 ! SH23A_HUMAN relationship: has_participant CCO:B0058911 ! TNR19_HUMAN relationship: has_participant CCO:B0059419 ! DUS10_HUMAN [Term] id: CCO:P0000773 name: activation of JNKK activity namespace: biological_process def: "The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress." [GOC:bf, PMID:11790549] synonym: "activation of JUN kinase kinase activity" EXACT [] synonym: "positive regulation of JUNKK activity" BROAD [] xref: GO:0007256 is_a: CCO:P0000410 ! activation of MAPKK activity relationship: has_participant CCO:B0057451 ! PGBD3_HUMAN relationship: part_of CCO:P0000772 ! JNK cascade [Term] id: CCO:P0000774 name: activation of JNK activity namespace: biological_process def: "The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK)." [GOC:bf] synonym: "activation of JUN kinase activity" EXACT [] synonym: "activation of SAPK activity" BROAD [] xref: GO:0007257 is_a: CCO:P0000411 ! activation of MAPK activity relationship: has_participant CCO:B0001820 ! M3K11_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN relationship: has_participant CCO:B0006068 ! PKN1_HUMAN relationship: has_participant CCO:B0018759 ! M3KL4_HUMAN relationship: has_participant CCO:B0018770 ! M3K10_HUMAN relationship: has_participant CCO:B0038544 ! M3K9_HUMAN relationship: has_participant CCO:B0042830 ! FCERA_HUMAN relationship: has_participant CCO:B0054754 ! M3K6_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN relationship: has_participant CCO:B0057451 ! PGBD3_HUMAN relationship: has_participant CCO:B0058112 ! M4K1_HUMAN relationship: has_participant CCO:B0058181 ! BIRC7_HUMAN relationship: has_participant CCO:B0059026 ! PTAD1_HUMAN relationship: has_participant CCO:B0059043 ! MDFIC_HUMAN relationship: has_participant CCO:B0059177 ! DBNL_HUMAN relationship: has_participant CCO:B0059318 ! M3K2_HUMAN relationship: has_participant CCO:B0059365 ! M4K5_HUMAN relationship: part_of CCO:P0000772 ! JNK cascade [Term] id: CCO:P0000775 name: JUN phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into a JUN protein." [GOC:jl] xref: GO:0007258 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005638 ! MK08_HUMAN relationship: part_of CCO:P0000772 ! JNK cascade [Term] id: CCO:P0000776 name: JAK-STAT cascade namespace: biological_process def: "Any process by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of cytokines to their cognate receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes." [GOC:jl, PMID:12039028] xref: GO:0007259 is_a: CCO:P0000767 ! protein kinase cascade relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001757 ! PKD2_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN relationship: has_participant CCO:B0005695 ! NMI_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN relationship: has_participant CCO:B0023418 ! STAT4_HUMAN relationship: has_participant CCO:B0023422 ! STAT2_HUMAN relationship: has_participant CCO:B0038965 ! CCL2_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0054349 ! SOCS6_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0055085 ! INAR1_HUMAN relationship: has_participant CCO:B0055344 ! CCR2_HUMAN relationship: has_participant CCO:B0055406 ! INAR2_HUMAN relationship: has_participant CCO:B0059022 ! Q9NZX6_HUMAN relationship: has_participant CCO:B0059069 ! CLCF1_HUMAN [Term] id: CCO:P0000777 name: tyrosine phosphorylation of STAT protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:10918594] xref: GO:0007260 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: part_of CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0000778 name: JAK-induced STAT protein dimerization namespace: biological_process def: "The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases." [GOC:jl, PMID:12039028] xref: GO:0007261 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0000779 name: STAT protein nuclear translocation namespace: biological_process def: "The transport of dimerized STAT (Signal Transducers and Activators of Transcription) proteins into the nucleus following activation by members of the janus activated kinase (JAK) family of tyrosine kinases." [GOC:jl, PMID:12039028] xref: GO:0007262 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: part_of CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0000780 name: nitric oxide mediated signal transduction namespace: biological_process def: "A series of molecular signals mediated by the detection of nitric oxide (NO)." [GOC:jl] synonym: "nitric oxide-mediated signal transduction" EXACT [] synonym: "NO mediated signal transduction" EXACT [] synonym: "NO-mediated signal transduction" EXACT [] xref: GO:0007263 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0027200 ! FPR1_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0036805 ! PDX1_HUMAN relationship: has_participant CCO:B0042185 ! MAFA_HUMAN relationship: has_participant CCO:B0054696 ! DDAH1_HUMAN relationship: has_participant CCO:B0054801 ! DDAH2_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0054877 ! MT2_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055705 ! GCYA3_HUMAN relationship: has_participant CCO:B0055706 ! GCYB1_HUMAN relationship: has_participant CCO:B0055929 ! NDF1_HUMAN [Term] id: CCO:P0000781 name: small GTPase mediated signal transduction namespace: biological_process def: "Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals." [GOC:mah] subset: gosubset_prok xref: GO:0007264 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0001384 ! SIAH2_HUMAN relationship: has_participant CCO:B0001437 ! BCAR3_HUMAN relationship: has_participant CCO:B0001453 ! DIRA3_HUMAN relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001692 ! RHOB_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0001694 ! RAP1A_HUMAN relationship: has_participant CCO:B0001704 ! RHOG_HUMAN relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0005237 ! RB22A_HUMAN relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN relationship: has_participant CCO:B0005802 ! DOCK1_HUMAN relationship: has_participant CCO:B0005836 ! ACK1_HUMAN relationship: has_participant CCO:B0005851 ! DIRA2_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0005913 ! BRAF1_HUMAN relationship: has_participant CCO:B0006120 ! ARL3_HUMAN relationship: has_participant CCO:B0006222 ! RAB1A_HUMAN relationship: has_participant CCO:B0006223 ! RB27A_HUMAN relationship: has_participant CCO:B0006229 ! RIT1_HUMAN relationship: has_participant CCO:B0006256 ! ARL4D_HUMAN relationship: has_participant CCO:B0006324 ! ARL8B_HUMAN relationship: has_participant CCO:B0015284 ! ARF3_HUMAN relationship: has_participant CCO:B0015288 ! ARF1_HUMAN relationship: has_participant CCO:B0016257 ! Q9BR65_HUMAN relationship: has_participant CCO:B0016356 ! Q6KH11_HUMAN relationship: has_participant CCO:B0016357 ! Q6PCE1_HUMAN relationship: has_participant CCO:B0016358 ! Q495L7_HUMAN relationship: has_participant CCO:B0016364 ! Q5T7U6_HUMAN relationship: has_participant CCO:B0016366 ! Q9P2N8_HUMAN relationship: has_participant CCO:B0016367 ! RGL3_HUMAN relationship: has_participant CCO:B0016368 ! Q8TEP0_HUMAN relationship: has_participant CCO:B0016369 ! Q6ZSD5_HUMAN relationship: has_participant CCO:B0016807 ! PDK1_HUMAN relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN relationship: has_participant CCO:B0018007 ! RRAS_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN relationship: has_participant CCO:B0018391 ! IQGA2_HUMAN relationship: has_participant CCO:B0018395 ! IQGA3_HUMAN relationship: has_participant CCO:B0019383 ! RHG05_HUMAN relationship: has_participant CCO:B0020556 ! PLD1_HUMAN relationship: has_participant CCO:B0020561 ! PLD2_HUMAN relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0020594 ! RHOC_HUMAN relationship: has_participant CCO:B0020597 ! Q5JR08_HUMAN relationship: has_participant CCO:B0020776 ! RGS19_HUMAN relationship: has_participant CCO:B0020850 ! Q9P1K2_HUMAN relationship: has_participant CCO:B0022936 ! Q5TEW3_HUMAN relationship: has_participant CCO:B0023550 ! RAB5C_HUMAN relationship: has_participant CCO:B0023551 ! RAB5A_HUMAN relationship: has_participant CCO:B0023553 ! RAB5B_HUMAN relationship: has_participant CCO:B0023961 ! Q8NIA3_HUMAN relationship: has_participant CCO:B0024398 ! RAP2B_HUMAN relationship: has_participant CCO:B0024399 ! Q5U0C3_HUMAN relationship: has_participant CCO:B0024403 ! A6NNR4_HUMAN relationship: has_participant CCO:B0024404 ! RAP2A_HUMAN relationship: has_participant CCO:B0024407 ! RAP2C_HUMAN relationship: has_participant CCO:B0024408 ! Q9BXV4_HUMAN relationship: has_participant CCO:B0024410 ! RAP1B_HUMAN relationship: has_participant CCO:B0025350 ! DIRA1_HUMAN relationship: has_participant CCO:B0025802 ! RAC2_HUMAN relationship: has_participant CCO:B0025814 ! RAC3_HUMAN relationship: has_participant CCO:B0026021 ! RAB1B_HUMAN relationship: has_participant CCO:B0027846 ! A8K4V1_HUMAN relationship: has_participant CCO:B0028281 ! ARL1_HUMAN relationship: has_participant CCO:B0030277 ! RND3_HUMAN relationship: has_participant CCO:B0030278 ! RND1_HUMAN relationship: has_participant CCO:B0030280 ! RND2_HUMAN relationship: has_participant CCO:B0031984 ! RBL2A_HUMAN relationship: has_participant CCO:B0031985 ! Q8WUI7_HUMAN relationship: has_participant CCO:B0031988 ! RBL2B_HUMAN relationship: has_participant CCO:B0032548 ! RAB8A_HUMAN relationship: has_participant CCO:B0032549 ! RAB10_HUMAN relationship: has_participant CCO:B0032550 ! RAB8B_HUMAN relationship: has_participant CCO:B0032555 ! RAB13_HUMAN relationship: has_participant CCO:B0032556 ! Q504R6_HUMAN relationship: has_participant CCO:B0037994 ! RGPS2_HUMAN relationship: has_participant CCO:B0037997 ! Q5JT61_HUMAN relationship: has_participant CCO:B0038000 ! Q5JS12_HUMAN relationship: has_participant CCO:B0038002 ! Q8N7G9_HUMAN relationship: has_participant CCO:B0038385 ! RPGF1_HUMAN relationship: has_participant CCO:B0038386 ! Q5JUE5_HUMAN relationship: has_participant CCO:B0038390 ! Q5JUE9_HUMAN relationship: has_participant CCO:B0038391 ! Q8IV73_HUMAN relationship: has_participant CCO:B0038434 ! RB11B_HUMAN relationship: has_participant CCO:B0038438 ! RB11A_HUMAN relationship: has_participant CCO:B0039886 ! RHEB_HUMAN relationship: has_participant CCO:B0040684 ! REBL1_HUMAN relationship: has_participant CCO:B0042581 ! B1AMV0_HUMAN relationship: has_participant CCO:B0042582 ! B1AMV1_HUMAN relationship: has_participant CCO:B0042583 ! B1AMV2_HUMAN relationship: has_participant CCO:B0048898 ! RGPS1_HUMAN relationship: has_participant CCO:B0051199 ! RP1BL_HUMAN relationship: has_participant CCO:B0053747 ! A3KN82_HUMAN relationship: has_participant CCO:B0053752 ! RAB19_HUMAN relationship: has_participant CCO:B0053753 ! A4D1S6_HUMAN relationship: has_participant CCO:B0053761 ! A4D2P2_HUMAN relationship: has_participant CCO:B0053777 ! A5XEI4_HUMAN relationship: has_participant CCO:B0053778 ! A5XEI5_HUMAN relationship: has_participant CCO:B0053779 ! A5XEI9_HUMAN relationship: has_participant CCO:B0053791 ! RB43L_HUMAN relationship: has_participant CCO:B0053794 ! A6NDQ6_HUMAN relationship: has_participant CCO:B0053795 ! A6NDS3_HUMAN relationship: has_participant CCO:B0053840 ! ARL5C_HUMAN relationship: has_participant CCO:B0053846 ! A6NHE2_HUMAN relationship: has_participant CCO:B0053859 ! A6NIB0_HUMAN relationship: has_participant CCO:B0053867 ! A6NJ28_HUMAN relationship: has_participant CCO:B0053906 ! A6NMI4_HUMAN relationship: has_participant CCO:B0053922 ! A6NNY6_HUMAN relationship: has_participant CCO:B0053983 ! A8K9Z8_HUMAN relationship: has_participant CCO:B0053993 ! A8MQ07_HUMAN relationship: has_participant CCO:B0054010 ! A8MSP2_HUMAN relationship: has_participant CCO:B0054012 ! A8MST8_HUMAN relationship: has_participant CCO:B0054013 ! A8MSV0_HUMAN relationship: has_participant CCO:B0054014 ! A8MSV4_HUMAN relationship: has_participant CCO:B0054023 ! A8MTC6_HUMAN relationship: has_participant CCO:B0054047 ! A8MUU7_HUMAN relationship: has_participant CCO:B0054096 ! A8MXF5_HUMAN relationship: has_participant CCO:B0054126 ! A8MYQ9_HUMAN relationship: has_participant CCO:B0054129 ! A8MYT0_HUMAN relationship: has_participant CCO:B0054141 ! A8MZG4_HUMAN relationship: has_participant CCO:B0054143 ! A8MZI4_HUMAN relationship: has_participant CCO:B0054203 ! B1AH57_HUMAN relationship: has_participant CCO:B0054204 ! B1AH58_HUMAN relationship: has_participant CCO:B0054205 ! B1AH77_HUMAN relationship: has_participant CCO:B0054206 ! B1AH78_HUMAN relationship: has_participant CCO:B0054207 ! B1AH80_HUMAN relationship: has_participant CCO:B0054257 ! B1AMX3_HUMAN relationship: has_participant CCO:B0054297 ! RB27B_HUMAN relationship: has_participant CCO:B0054300 ! RHOD_HUMAN relationship: has_participant CCO:B0054330 ! KRIT1_HUMAN relationship: has_participant CCO:B0054379 ! RASM_HUMAN relationship: has_participant CCO:B0054381 ! RGRF2_HUMAN relationship: has_participant CCO:B0054394 ! RAB7L_HUMAN relationship: has_participant CCO:B0054416 ! RGL2_HUMAN relationship: has_participant CCO:B0054659 ! REM1_HUMAN relationship: has_participant CCO:B0054664 ! O75761_HUMAN relationship: has_participant CCO:B0054704 ! RHBT1_HUMAN relationship: has_participant CCO:B0054743 ! GRP1_HUMAN relationship: has_participant CCO:B0054757 ! RPGF3_HUMAN relationship: has_participant CCO:B0054785 ! RAB3D_HUMAN relationship: has_participant CCO:B0054792 ! RAB36_HUMAN relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0054892 ! NTRK1_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0054953 ! RB40L_HUMAN relationship: has_participant CCO:B0054988 ! RALA_HUMAN relationship: has_participant CCO:B0054989 ! RALB_HUMAN relationship: has_participant CCO:B0055081 ! RHOQ_HUMAN relationship: has_participant CCO:B0055099 ! ARF4_HUMAN relationship: has_participant CCO:B0055116 ! RAB3A_HUMAN relationship: has_participant CCO:B0055117 ! RAB3B_HUMAN relationship: has_participant CCO:B0055118 ! RAB6A_HUMAN relationship: has_participant CCO:B0055233 ! GDIA_HUMAN relationship: has_participant CCO:B0055307 ! ARL2_HUMAN relationship: has_participant CCO:B0055308 ! ARD1_HUMAN relationship: has_participant CCO:B0055331 ! ARL4A_HUMAN relationship: has_participant CCO:B0055383 ! MSS4_HUMAN relationship: has_participant CCO:B0055457 ! RAB7A_HUMAN relationship: has_participant CCO:B0055458 ! RAB9A_HUMAN relationship: has_participant CCO:B0055459 ! RAB28_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN relationship: has_participant CCO:B0055508 ! ARFP2_HUMAN relationship: has_participant CCO:B0055523 ! GEM_HUMAN relationship: has_participant CCO:B0055524 ! RAD_HUMAN relationship: has_participant CCO:B0055560 ! RAB25_HUMAN relationship: has_participant CCO:B0055575 ! RAB15_HUMAN relationship: has_participant CCO:B0055601 ! RAB4B_HUMAN relationship: has_participant CCO:B0055602 ! RAB2A_HUMAN relationship: has_participant CCO:B0055604 ! RAB14_HUMAN relationship: has_participant CCO:B0055616 ! ARF6_HUMAN relationship: has_participant CCO:B0055662 ! ARF5_HUMAN relationship: has_participant CCO:B0055759 ! Q05D03_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN relationship: has_participant CCO:B0055810 ! Q0EFC9_HUMAN relationship: has_participant CCO:B0055822 ! RGF1B_HUMAN relationship: has_participant CCO:B0055845 ! RB40B_HUMAN relationship: has_participant CCO:B0055861 ! ABR_HUMAN relationship: has_participant CCO:B0055936 ! RAB32_HUMAN relationship: has_participant CCO:B0055942 ! ARFRP_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: has_participant CCO:B0055955 ! Q14007_HUMAN relationship: has_participant CCO:B0055956 ! RB33A_HUMAN relationship: has_participant CCO:B0056028 ! RB39A_HUMAN relationship: has_participant CCO:B0056053 ! Q15285_HUMAN relationship: has_participant CCO:B0056054 ! RAB35_HUMAN relationship: has_participant CCO:B0056057 ! RBP1_HUMAN relationship: has_participant CCO:B0056094 ! RHOH_HUMAN relationship: has_participant CCO:B0056108 ! RAB30_HUMAN relationship: has_participant CCO:B0056141 ! Q16525_HUMAN relationship: has_participant CCO:B0056195 ! Q1W5D8_HUMAN relationship: has_participant CCO:B0056243 ! LRRK1_HUMAN relationship: has_participant CCO:B0056279 ! PARF_HUMAN relationship: has_participant CCO:B0056282 ! Q3ZCN2_HUMAN relationship: has_participant CCO:B0056299 ! ARF1L_HUMAN relationship: has_participant CCO:B0056309 ! Q4A519_HUMAN relationship: has_participant CCO:B0056314 ! Q4G0R5_HUMAN relationship: has_participant CCO:B0056352 ! Q53EY4_HUMAN relationship: has_participant CCO:B0056359 ! Q53GC2_HUMAN relationship: has_participant CCO:B0056364 ! Q53S08_HUMAN relationship: has_participant CCO:B0056370 ! Q54AJ0_HUMAN relationship: has_participant CCO:B0056372 ! Q569L6_HUMAN relationship: has_participant CCO:B0056373 ! Q56UN9_HUMAN relationship: has_participant CCO:B0056380 ! RUN3A_HUMAN relationship: has_participant CCO:B0056382 ! Q59EP4_HUMAN relationship: has_participant CCO:B0056394 ! Q59FQ0_HUMAN relationship: has_participant CCO:B0056444 ! RABL3_HUMAN relationship: has_participant CCO:B0056452 ! Q5JPD2_HUMAN relationship: has_participant CCO:B0056460 ! Q5JR05_HUMAN relationship: has_participant CCO:B0056461 ! Q5JR06_HUMAN relationship: has_participant CCO:B0056462 ! Q5JR07_HUMAN relationship: has_participant CCO:B0056481 ! RAB41_HUMAN relationship: has_participant CCO:B0056484 ! Q5JU31_HUMAN relationship: has_participant CCO:B0056487 ! Q5JUE7_HUMAN relationship: has_participant CCO:B0056512 ! Q5JYX0_HUMAN relationship: has_participant CCO:B0056531 ! LRRK2_HUMAN relationship: has_participant CCO:B0056617 ! Q5TEV6_HUMAN relationship: has_participant CCO:B0056664 ! Q5VWL4_HUMAN relationship: has_participant CCO:B0056667 ! Q5VY89_HUMAN relationship: has_participant CCO:B0056678 ! Q5W0I9_HUMAN relationship: has_participant CCO:B0056679 ! Q5W0J0_HUMAN relationship: has_participant CCO:B0056826 ! RAB12_HUMAN relationship: has_participant CCO:B0056840 ! Q6MZH2_HUMAN relationship: has_participant CCO:B0056861 ! Q6NUQ6_HUMAN relationship: has_participant CCO:B0056872 ! Q6NZ33_HUMAN relationship: has_participant CCO:B0056913 ! Q6PIK3_HUMAN relationship: has_participant CCO:B0056944 ! RSLBA_HUMAN relationship: has_participant CCO:B0056945 ! ARL9_HUMAN relationship: has_participant CCO:B0057014 ! Q6ZN78_HUMAN relationship: has_participant CCO:B0057049 ! Q6ZS74_HUMAN relationship: has_participant CCO:B0057097 ! Q71SP6_HUMAN relationship: has_participant CCO:B0057109 ! VKIND_HUMAN relationship: has_participant CCO:B0057113 ! RHOU_HUMAN relationship: has_participant CCO:B0057123 ! GRP2_HUMAN relationship: has_participant CCO:B0057161 ! RASE_HUMAN relationship: has_participant CCO:B0057169 ! Q7Z4W7_HUMAN relationship: has_participant CCO:B0057199 ! RAB44_HUMAN relationship: has_participant CCO:B0057235 ! Q86ST5_HUMAN relationship: has_participant CCO:B0057311 ! RAB43_HUMAN relationship: has_participant CCO:B0057328 ! Q8IUU5_HUMAN relationship: has_participant CCO:B0057337 ! GRP3_HUMAN relationship: has_participant CCO:B0057357 ! Q8IWA7_HUMAN relationship: has_participant CCO:B0057377 ! MIRO2_HUMAN relationship: has_participant CCO:B0057378 ! MIRO1_HUMAN relationship: has_participant CCO:B0057389 ! REM2_HUMAN relationship: has_participant CCO:B0057398 ! RASEF_HUMAN relationship: has_participant CCO:B0057408 ! RGDSR_HUMAN relationship: has_participant CCO:B0057460 ! RGF1C_HUMAN relationship: has_participant CCO:B0057461 ! Q8N437_HUMAN relationship: has_participant CCO:B0057463 ! GUF1_HUMAN relationship: has_participant CCO:B0057466 ! ARL14_HUMAN relationship: has_participant CCO:B0057468 ! RAB42_HUMAN relationship: has_participant CCO:B0057474 ! SH2D3_HUMAN relationship: has_participant CCO:B0057500 ! Q8N798_HUMAN relationship: has_participant CCO:B0057524 ! ARL10_HUMAN relationship: has_participant CCO:B0057535 ! RGF1A_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: has_participant CCO:B0057952 ! Q8TEA3_HUMAN relationship: has_participant CCO:B0057956 ! RPGF6_HUMAN relationship: has_participant CCO:B0057977 ! RAB2B_HUMAN relationship: has_participant CCO:B0057991 ! Q8WVF3_HUMAN relationship: has_participant CCO:B0058021 ! RB40A_HUMAN relationship: has_participant CCO:B0058040 ! Q8WY67_HUMAN relationship: has_participant CCO:B0058047 ! RIN2_HUMAN relationship: has_participant CCO:B0058055 ! RPGF4_HUMAN relationship: has_participant CCO:B0058064 ! RPGF5_HUMAN relationship: has_participant CCO:B0058080 ! Q92668_HUMAN relationship: has_participant CCO:B0058085 ! RSLAA_HUMAN relationship: has_participant CCO:B0058113 ! Q92942_HUMAN relationship: has_participant CCO:B0058138 ! ARL11_HUMAN relationship: has_participant CCO:B0058139 ! RAB24_HUMAN relationship: has_participant CCO:B0058147 ! RERG_HUMAN relationship: has_participant CCO:B0058153 ! RAB7B_HUMAN relationship: has_participant CCO:B0058157 ! RAB37_HUMAN relationship: has_participant CCO:B0058166 ! ARL8A_HUMAN relationship: has_participant CCO:B0058189 ! RHES_HUMAN relationship: has_participant CCO:B0058191 ! RB39B_HUMAN relationship: has_participant CCO:B0058200 ! RAB3C_HUMAN relationship: has_participant CCO:B0058250 ! Q96K32_HUMAN relationship: has_participant CCO:B0058257 ! ARL5B_HUMAN relationship: has_participant CCO:B0058264 ! RHOV_HUMAN relationship: has_participant CCO:B0058317 ! CENG3_HUMAN relationship: has_participant CCO:B0058336 ! Q96PJ7_HUMAN relationship: has_participant CCO:B0058384 ! RB40C_HUMAN relationship: has_participant CCO:B0058388 ! RSLAB_HUMAN relationship: has_participant CCO:B0058399 ! Q96T27_HUMAN relationship: has_participant CCO:B0058417 ! CENG1_HUMAN relationship: has_participant CCO:B0058426 ! RIT2_HUMAN relationship: has_participant CCO:B0058435 ! CHP1_HUMAN relationship: has_participant CCO:B0058470 ! RSLBB_HUMAN relationship: has_participant CCO:B0058491 ! SH23A_HUMAN relationship: has_participant CCO:B0058517 ! CA089_HUMAN relationship: has_participant CCO:B0058530 ! RAYL_HUMAN relationship: has_participant CCO:B0058588 ! RHBT2_HUMAN relationship: has_participant CCO:B0058598 ! RAB34_HUMAN relationship: has_participant CCO:B0058607 ! Q9BZT2_HUMAN relationship: has_participant CCO:B0058649 ! RB33B_HUMAN relationship: has_participant CCO:B0058652 ! ARL6_HUMAN relationship: has_participant CCO:B0058655 ! RAB6C_HUMAN relationship: has_participant CCO:B0058657 ! RAB17_HUMAN relationship: has_participant CCO:B0058664 ! Q9H1C9_HUMAN relationship: has_participant CCO:B0058716 ! RHOJ_HUMAN relationship: has_participant CCO:B0058732 ! RERGL_HUMAN relationship: has_participant CCO:B0058760 ! Q9HAG2_HUMAN relationship: has_participant CCO:B0058781 ! RRAGC_HUMAN relationship: has_participant CCO:B0058784 ! RHOF_HUMAN relationship: has_participant CCO:B0058813 ! GPN1_HUMAN relationship: has_participant CCO:B0058825 ! Q9HD57_HUMAN relationship: has_participant CCO:B0058836 ! RAB18_HUMAN relationship: has_participant CCO:B0058841 ! RAB9B_HUMAN relationship: has_participant CCO:B0058885 ! SAR1A_HUMAN relationship: has_participant CCO:B0058905 ! RAB6B_HUMAN relationship: has_participant CCO:B0058949 ! RAB20_HUMAN relationship: has_participant CCO:B0058966 ! RASLC_HUMAN relationship: has_participant CCO:B0058969 ! KBRS2_HUMAN relationship: has_participant CCO:B0058970 ! KBRS1_HUMAN relationship: has_participant CCO:B0059009 ! RABJ_HUMAN relationship: has_participant CCO:B0059026 ! PTAD1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059149 ! Q9UHV4_HUMAN relationship: has_participant CCO:B0059150 ! RPGFL_HUMAN relationship: has_participant CCO:B0059207 ! VAV3_HUMAN relationship: has_participant CCO:B0059214 ! RAB21_HUMAN relationship: has_participant CCO:B0059215 ! Q9UL31_HUMAN relationship: has_participant CCO:B0059221 ! RAB23_HUMAN relationship: has_participant CCO:B0059236 ! RAB26_HUMAN relationship: has_participant CCO:B0059263 ! CENG2_HUMAN relationship: has_participant CCO:B0059295 ! RASD1_HUMAN relationship: has_participant CCO:B0059358 ! MFHA1_HUMAN relationship: has_participant CCO:B0059362 ! RPGF2_HUMAN relationship: has_participant CCO:B0059399 ! ARL5A_HUMAN relationship: has_participant CCO:B0059403 ! SAR1B_HUMAN [Term] id: CCO:P0000782 name: Ras protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state." [GOC:bf] synonym: "Ras mediated signal transduction" EXACT [] xref: GO:0007265 is_a: CCO:P0000781 ! small GTPase mediated signal transduction relationship: has_participant CCO:B0001369 ! MK13_HUMAN relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001467 ! RASH_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001560 ! MK03_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001665 ! MK12_HUMAN relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0002162 ! RASF1_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005443 ! PARK7_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005464 ! SRC_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005650 ! SHOC2_HUMAN relationship: has_participant CCO:B0005892 ! MK11_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0017421 ! MP2K2_HUMAN relationship: has_participant CCO:B0018007 ! RRAS_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN relationship: has_participant CCO:B0020556 ! PLD1_HUMAN relationship: has_participant CCO:B0021108 ! MK14_HUMAN relationship: has_participant CCO:B0028327 ! G3BP2_HUMAN relationship: has_participant CCO:B0028328 ! G3BP1_HUMAN relationship: has_participant CCO:B0054379 ! RASM_HUMAN relationship: has_participant CCO:B0054416 ! RGL2_HUMAN relationship: has_participant CCO:B0054492 ! LAT_HUMAN relationship: has_participant CCO:B0054562 ! DOK2_HUMAN relationship: has_participant CCO:B0054628 ! ULK1_HUMAN relationship: has_participant CCO:B0054668 ! GRAP2_HUMAN relationship: has_participant CCO:B0054743 ! GRP1_HUMAN relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0054853 ! IGF1A_HUMAN relationship: has_participant CCO:B0054892 ! NTRK1_HUMAN relationship: has_participant CCO:B0054937 ! ADA2A_HUMAN relationship: has_participant CCO:B0054988 ! RALA_HUMAN relationship: has_participant CCO:B0054989 ! RALB_HUMAN relationship: has_participant CCO:B0055377 ! CRKL_HUMAN relationship: has_participant CCO:B0055417 ! MAPK2_HUMAN relationship: has_participant CCO:B0055621 ! GBB1_HUMAN relationship: has_participant CCO:B0055667 ! SHC2_HUMAN relationship: has_participant CCO:B0055933 ! GRAP_HUMAN relationship: has_participant CCO:B0056166 ! MAPK3_HUMAN relationship: has_participant CCO:B0057120 ! DOK3_HUMAN relationship: has_participant CCO:B0057123 ! GRP2_HUMAN relationship: has_participant CCO:B0057337 ! GRP3_HUMAN relationship: has_participant CCO:B0057348 ! KSR1_HUMAN relationship: has_participant CCO:B0057956 ! RPGF6_HUMAN relationship: has_participant CCO:B0058060 ! SHC3_HUMAN relationship: has_participant CCO:B0058091 ! RREB1_HUMAN relationship: has_participant CCO:B0058131 ! CNKR1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN [Term] id: CCO:P0000783 name: Rho protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state." [GOC:bf] synonym: "Rho mediated signal transduction" EXACT [] xref: GO:0007266 is_a: CCO:P0000782 ! Ras protein signal transduction relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001692 ! RHOB_HUMAN relationship: has_participant CCO:B0001704 ! RHOG_HUMAN relationship: has_participant CCO:B0002023 ! ARHG1_HUMAN relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN relationship: has_participant CCO:B0019383 ! RHG05_HUMAN relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0031122 ! MYO9B_HUMAN relationship: has_participant CCO:B0032833 ! GDIR1_HUMAN relationship: has_participant CCO:B0033320 ! COF1_HUMAN relationship: has_participant CCO:B0054300 ! RHOD_HUMAN relationship: has_participant CCO:B0054390 ! TX1B3_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN relationship: has_participant CCO:B0054455 ! RHG06_HUMAN relationship: has_participant CCO:B0054847 ! PTHY_HUMAN relationship: has_participant CCO:B0054937 ! ADA2A_HUMAN relationship: has_participant CCO:B0055486 ! GDIR2_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0055558 ! SYJ2B_HUMAN relationship: has_participant CCO:B0055675 ! RHG04_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN relationship: has_participant CCO:B0055787 ! RHG01_HUMAN relationship: has_participant CCO:B0055910 ! ROCK1_HUMAN relationship: has_participant CCO:B0056343 ! RHG29_HUMAN relationship: has_participant CCO:B0056874 ! BORG3_HUMAN relationship: has_participant CCO:B0058131 ! CNKR1_HUMAN relationship: has_participant CCO:B0058457 ! GDIR3_HUMAN relationship: has_participant CCO:B0058510 ! RTKN_HUMAN relationship: has_participant CCO:B0058611 ! ROP1B_HUMAN relationship: has_participant CCO:B0058716 ! RHOJ_HUMAN relationship: has_participant CCO:B0058889 ! ARHG3_HUMAN [Term] id: CCO:P0000784 name: cystoblast division namespace: biological_process def: "The four rounds of incomplete mitosis undergone by the cystoblast to form a 16-cell cyst. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells." [PMID:11131529] synonym: "cystoblast cell division" EXACT [] xref: GO:0007282 is_a: CCO:P0000821 ! asymmetric cell division [Term] id: CCO:P0000785 name: spermatogonial cell division namespace: biological_process def: "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form a cyst of secondary spermatogonia (primary spermatocytes)." [GOC:bf, ISBN:0879694238] comment: See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'. xref: GO:0007284 is_a: CCO:P0003077 ! cell division relationship: part_of CCO:P0002777 ! male germ-line cyst formation [Term] id: CCO:P0000786 name: eggshell chorion gene amplification namespace: biological_process def: "Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster." [GOC:mtg_sensu, PMID:11157771] xref: GO:0007307 is_a: CCO:P0000640 ! DNA amplification [Term] id: CCO:P0000787 name: negative regulation of oskar mRNA translation namespace: biological_process def: "Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein." [GOC:ems] synonym: "down regulation of oskar mRNA translation" EXACT [] synonym: "down-regulation of oskar mRNA translation" EXACT [] synonym: "downregulation of oskar mRNA translation" EXACT [] synonym: "inhibition of oskar mRNA translation" NARROW [] xref: GO:0007319 is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0002673 ! regulation of oskar mRNA translation [Term] id: CCO:P0000788 name: positive regulation of transcription from RNA polymerase II promoter by pheromones namespace: biological_process def: "Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter." [GOC:go_curators] synonym: "activation of transcription from RNA polymerase II promoter by pheromones" NARROW [] synonym: "positive regulation of transcription from Pol II promoter by pheromones" EXACT [] synonym: "stimulation of transcription from RNA polymerase II promoter by pheromones" NARROW [] synonym: "up regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] synonym: "up-regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] synonym: "upregulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] xref: GO:0007329 is_a: CCO:P0000848 ! positive regulation of transcription by pheromones is_a: CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter is_a: CCO:P0002679 ! regulation of transcription from RNA polymerase II promoter by pheromones [Term] id: CCO:P0000789 name: positive regulation of central gap gene transcription namespace: biological_process def: "The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] synonym: "activation of central gap gene" BROAD [] synonym: "activation of central gap gene transcription" NARROW [] synonym: "stimulation of central gap gene transcription" NARROW [] synonym: "up regulation of central gap gene transcription" EXACT [] synonym: "up-regulation of central gap gene transcription" EXACT [] synonym: "upregulation of central gap gene transcription" EXACT [] xref: GO:0007357 is_a: CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0000790 name: positive regulation of posterior gap gene transcription namespace: biological_process def: "The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] synonym: "activation of posterior gap gene" BROAD [] synonym: "activation of posterior gap gene transcription" NARROW [] synonym: "knirps activation" NARROW [] synonym: "stimulation of posterior gap gene transcription" NARROW [] synonym: "up regulation of posterior gap gene transcription" EXACT [] synonym: "up-regulation of posterior gap gene transcription" EXACT [] synonym: "upregulation of posterior gap gene transcription" EXACT [] xref: GO:0007360 is_a: CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0000791 name: positive regulation of terminal gap gene transcription namespace: biological_process def: "The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] synonym: "activation of terminal gap gene" BROAD [] synonym: "activation of terminal gap gene transcription" NARROW [] synonym: "stimulation of terminal gap gene transcription" NARROW [] synonym: "up regulation of terminal gap gene transcription" EXACT [] synonym: "up-regulation of terminal gap gene transcription" EXACT [] synonym: "upregulation of terminal gap gene transcription" EXACT [] xref: GO:0007363 is_a: CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0000792 name: dorsal closure, elongation of leading edge cells namespace: biological_process def: "The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis." [PMID:12147138] xref: GO:0007394 is_a: CCO:P0001126 ! regulation of embryonic cell shape [Term] id: CCO:P0000793 name: neuroblast proliferation namespace: biological_process def: "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart] synonym: "neuroblast proliferation (sensu Nematoda and Protostomia)" EXACT [] synonym: "neuroblast proliferation (sensu Vertebrata)" EXACT [] xref: GO:0007405 xref: GO:0043349 xref: GO:0043350 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN relationship: has_participant CCO:B0015164 ! HHIP_HUMAN relationship: has_participant CCO:B0022226 ! ID4_HUMAN relationship: has_participant CCO:B0038861 ! FZD9_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056578 ! ARTN_HUMAN relationship: has_participant CCO:B0057975 ! FRS2_HUMAN relationship: has_participant CCO:B0058828 ! NDF4_HUMAN relationship: has_participant CCO:B0059201 ! ACSL6_HUMAN relationship: has_participant CCO:B0059414 ! NUMBL_HUMAN [Term] id: CCO:P0000794 name: negative regulation of neuroblast proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai] synonym: "down regulation of neuroblast proliferation" EXACT [] synonym: "down-regulation of neuroblast proliferation" EXACT [] synonym: "downregulation of neuroblast proliferation" EXACT [] synonym: "inhibition of neuroblast proliferation" NARROW [] synonym: "suppression of neuroblast proliferation" EXACT [] xref: GO:0007406 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0002946 ! negative regulation of neurogenesis relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005824 ! CTNA1_HUMAN relationship: negatively_regulates CCO:P0000793 ! neuroblast proliferation [Term] id: CCO:P0000795 name: regulation of rhodopsin gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of rhodopsin gene activity" EXACT [GOC:dph, GOC:tb] xref: GO:0007468 is_a: CCO:P0000947 ! regulation of gene expression relationship: has_participant CCO:B0055518 ! NRL_HUMAN relationship: has_participant CCO:B0056140 ! RPE65_HUMAN [Term] id: CCO:P0000796 name: maintenance of imaginal histoblast diploidy namespace: biological_process def: "The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells." [GOC:bf, ISBN:0879694238] xref: GO:0007489 is_a: CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:P0000797 name: regulation of transcription, mating-type specific namespace: biological_process def: "Any mating-type specific process that modulates the frequency, rate or extent of transcription." [GOC:go_curators] synonym: "mating-type specific transcriptional control" EXACT [] xref: GO:0007532 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:P0000798 name: mating type switching namespace: biological_process def: "The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus." [PMID:9928492] synonym: "mating type switching and recombination" RELATED [] xref: GO:0007533 is_a: CCO:P0001240 ! reproductive process in single-celled organism [Term] id: CCO:P0000799 name: gene conversion at mating-type locus namespace: biological_process def: "The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged." [GOC:elh, PMID:9928492] xref: GO:0007534 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000798 ! mating type switching [Term] id: CCO:P0000800 name: donor selection namespace: biological_process def: "The process by which a cell uses one locus in preference to another as the donor in mating type switching." [GOC:mah, PMID:9928492] synonym: "donor preference" RELATED [] xref: GO:0007535 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000798 ! mating type switching [Term] id: CCO:P0000801 name: activation of recombination (HML) namespace: biological_process def: "The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae." [GOC:mah, PMID:9928492] xref: GO:0007536 is_a: CCO:P0000800 ! donor selection is_a: CCO:P0002608 ! positive regulation of DNA recombination [Term] id: CCO:P0000802 name: inactivation of recombination (HML) namespace: biological_process def: "The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae." [GOC:mah, PMID:9928492] xref: GO:0007537 is_a: CCO:P0000800 ! donor selection is_a: CCO:P0002607 ! negative regulation of DNA recombination [Term] id: CCO:P0000803 name: dosage compensation namespace: biological_process def: "Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes." [GOC:ems, ISBN:0140512888, PMID:11498577] xref: GO:0007549 is_a: CCO:P0002023 ! regulation of gene expression, epigenetic relationship: has_participant CCO:B0054625 ! H2AY_HUMAN relationship: has_participant CCO:B0059032 ! H2AW_HUMAN [Term] id: CCO:P0000804 name: regulation of ecdysteroid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "regulation of ecdysteroid metabolism" EXACT [] xref: GO:0007553 is_a: CCO:P0000987 ! regulation of ketone metabolic process is_a: CCO:P0001141 ! regulation of steroid metabolic process is_a: CCO:P0001608 ! regulation of hormone metabolic process [Term] id: CCO:P0000805 name: regulation of ecdysteroid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids." [GOC:go_curators] synonym: "regulation of ecdysteroid anabolism" EXACT [] synonym: "regulation of ecdysteroid biosynthesis" EXACT [] synonym: "regulation of ecdysteroid formation" EXACT [] synonym: "regulation of ecdysteroid synthesis" EXACT [] xref: GO:0007554 is_a: CCO:P0000804 ! regulation of ecdysteroid metabolic process is_a: CCO:P0000988 ! regulation of ketone biosynthetic process is_a: CCO:P0002745 ! regulation of hormone biosynthetic process is_a: CCO:P0002962 ! regulation of steroid biosynthetic process [Term] id: CCO:P0000806 name: regulation of ecdysteroid secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell or group of cells." [GOC:go_curators] xref: GO:0007555 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0000807 name: regulation of juvenile hormone metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators] synonym: "regulation of juvenile hormone metabolism" EXACT [] xref: GO:0007556 is_a: CCO:P0001146 ! regulation of isoprenoid metabolic process is_a: CCO:P0001608 ! regulation of hormone metabolic process [Term] id: CCO:P0000808 name: regulation of juvenile hormone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone." [GOC:go_curators] synonym: "regulation of juvenile hormone anabolism" EXACT [] synonym: "regulation of juvenile hormone biosynthesis" EXACT [] synonym: "regulation of juvenile hormone formation" EXACT [] synonym: "regulation of juvenile hormone synthesis" EXACT [] xref: GO:0007557 is_a: CCO:P0000807 ! regulation of juvenile hormone metabolic process is_a: CCO:P0002745 ! regulation of hormone biosynthetic process [Term] id: CCO:P0000809 name: regulation of juvenile hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of juvenile hormone secretion." [GOC:go_curators] xref: GO:0007558 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0000810 name: Toll signaling pathway namespace: biological_process def: "The series of molecular signals initiated by binding of a ligand to an extracellular ligand to the Toll receptor on the surface of the target cell." [GOC:go_curators] synonym: "Tl signaling pathway" EXACT [] synonym: "Tl signalling pathway" EXACT [] synonym: "Toll signalling pathway" EXACT [] xref: GO:0008063 xref: Reactome:166016 xref: Reactome:211663 xref: Reactome:221435 xref: Reactome:230067 xref: Reactome:238087 xref: Reactome:273985 xref: Reactome:280464 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:P0000811 name: regulation of actin polymerization and/or depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament." [GOC:mah] xref: GO:0008064 is_a: CCO:P0001325 ! regulation of actin filament length is_a: CCO:P0001572 ! regulation of cellular protein metabolic process relationship: has_participant CCO:B0006155 ! PROF2_HUMAN relationship: has_participant CCO:B0049176 ! TYB4Y_HUMAN relationship: has_participant CCO:B0055399 ! SDF1_HUMAN [Term] id: CCO:P0000812 name: decapentaplegic receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a decapentaplegic receptor binding to one of its physiological ligands." [GOC:ai] synonym: "decapentaplegic receptor signalling pathway" EXACT [] synonym: "dpp receptor signaling pathway" EXACT [] synonym: "dpp receptor signalling pathway" EXACT [] xref: GO:0008101 is_a: CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0000813 name: negative regulation of DNA replication namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication." [GOC:go_curators] subset: gosubset_prok synonym: "DNA replication inhibitor" RELATED [] synonym: "down regulation of DNA replication" EXACT [] synonym: "down-regulation of DNA replication" EXACT [] synonym: "downregulation of DNA replication" EXACT [] synonym: "inhibition of DNA replication" NARROW [] xref: GO:0008156 is_a: CCO:P0000639 ! regulation of DNA replication is_a: CCO:P0003016 ! negative regulation of DNA metabolic process relationship: has_participant CCO:B0001419 ! HUS1_HUMAN relationship: has_participant CCO:B0001432 ! GEMI_HUMAN relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0001756 ! ATR_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002116 ! NOG1_HUMAN relationship: has_participant CCO:B0002128 ! TSYL2_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN relationship: has_participant CCO:B0043733 ! TTF1_HUMAN relationship: has_participant CCO:B0056953 ! ENPP7_HUMAN relationship: negatively_regulates CCO:P0000628 ! DNA replication [Term] id: CCO:P0000814 name: regulation of G-protein coupled receptor protein signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity." [GOC:go_curators] synonym: "regulation of G protein coupled receptor protein signaling pathway" EXACT [] synonym: "regulation of G protein coupled receptor protein signalling pathway" EXACT [] synonym: "regulation of G-protein coupled receptor protein signalling pathway" EXACT [] synonym: "regulation of G-protein-coupled receptor protein signaling pathway" EXACT [] synonym: "regulation of G-protein-coupled receptor protein signalling pathway" EXACT [] synonym: "regulation of GPCR protein signaling pathway" EXACT [] synonym: "regulation of GPCR protein signalling pathway" EXACT [] xref: GO:0008277 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0020764 ! RGS20_HUMAN relationship: has_participant CCO:B0020766 ! RGS5_HUMAN relationship: has_participant CCO:B0020768 ! RGS16_HUMAN relationship: has_participant CCO:B0020771 ! RGS3_HUMAN relationship: has_participant CCO:B0020787 ! RGS18_HUMAN relationship: has_participant CCO:B0026710 ! RGS4_HUMAN relationship: has_participant CCO:B0033323 ! RGS12_HUMAN relationship: has_participant CCO:B0033332 ! RGS14_HUMAN relationship: has_participant CCO:B0049915 ! RAMP3_HUMAN relationship: has_participant CCO:B0053948 ! A7L9S6_HUMAN relationship: has_participant CCO:B0054537 ! GBG7_HUMAN relationship: has_participant CCO:B0054587 ! RAMP1_HUMAN relationship: has_participant CCO:B0054678 ! RGS9_HUMAN relationship: has_participant CCO:B0054700 ! RGS11_HUMAN relationship: has_participant CCO:B0055259 ! GRK4_HUMAN relationship: has_participant CCO:B0055271 ! GRK5_HUMAN relationship: has_participant CCO:B0055361 ! GRK6_HUMAN relationship: has_participant CCO:B0055433 ! RGS6_HUMAN relationship: has_participant CCO:B0055438 ! RGS7_HUMAN relationship: has_participant CCO:B0055443 ! GBG4_HUMAN relationship: has_participant CCO:B0055967 ! GIT2_HUMAN relationship: has_participant CCO:B0056115 ! RK_HUMAN relationship: has_participant CCO:B0056365 ! Q53SN3_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: has_participant CCO:B0058931 ! RIC8B_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: regulates CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0000815 name: cell proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb] subset: goslim_generic subset: goslim_pir subset: gosubset_prok xref: GO:0008283 is_a: CCO:P0000887 ! cellular process relationship: has_participant CCO:B0001349 ! BIN1_HUMAN relationship: has_participant CCO:B0001351 ! PESC_HUMAN relationship: has_participant CCO:B0001357 ! ANM5_HUMAN relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001395 ! BUB1_HUMAN relationship: has_participant CCO:B0001396 ! BUB3_HUMAN relationship: has_participant CCO:B0001402 ! VEGFD_HUMAN relationship: has_participant CCO:B0001408 ! EVI5_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001415 ! DKC1_HUMAN relationship: has_participant CCO:B0001438 ! TUSC2_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001472 ! IGF2_HUMAN relationship: has_participant CCO:B0001475 ! IL1A_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001477 ! IL2RA_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0001500 ! FGF4_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001503 ! DPOLA_HUMAN relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0001509 ! FGF6_HUMAN relationship: has_participant CCO:B0001511 ! FGF3_HUMAN relationship: has_participant CCO:B0001513 ! PCNA_HUMAN relationship: has_participant CCO:B0001514 ! FGF5_HUMAN relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0001544 ! MK_HUMAN relationship: has_participant CCO:B0001545 ! FGF7_HUMAN relationship: has_participant CCO:B0001550 ! KTHY_HUMAN relationship: has_participant CCO:B0001572 ! CDC27_HUMAN relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0001590 ! BTC_HUMAN relationship: has_participant CCO:B0001612 ! MATK_HUMAN relationship: has_participant CCO:B0001622 ! KI67_HUMAN relationship: has_participant CCO:B0001626 ! NASP_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001632 ! CLK1_HUMAN relationship: has_participant CCO:B0001633 ! PLGF_HUMAN relationship: has_participant CCO:B0001634 ! VEGFB_HUMAN relationship: has_participant CCO:B0001635 ! VEGFC_HUMAN relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0001642 ! ERF_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001647 ! CDK9_HUMAN relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0001671 ! BCAT1_HUMAN relationship: has_participant CCO:B0001674 ! FGF8_HUMAN relationship: has_participant CCO:B0001677 ! MTCPA_HUMAN relationship: has_participant CCO:B0001678 ! MTCPB_HUMAN relationship: has_participant CCO:B0001683 ! PROK1_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001691 ! RS4X_HUMAN relationship: has_participant CCO:B0001707 ! CDK3_HUMAN relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0001718 ! MP2K1_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0001749 ! SKP2_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0001765 ! PTC1_HUMAN relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0001776 ! TFDP1_HUMAN relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN relationship: has_participant CCO:B0001805 ! Q15354_HUMAN relationship: has_participant CCO:B0001807 ! DLGP5_HUMAN relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0001812 ! MARE1_HUMAN relationship: has_participant CCO:B0001813 ! UB2V2_HUMAN relationship: has_participant CCO:B0001820 ! M3K11_HUMAN relationship: has_participant CCO:B0001830 ! Q32M96_HUMAN relationship: has_participant CCO:B0001844 ! Q59FH5_HUMAN relationship: has_participant CCO:B0001898 ! GFI1B_HUMAN relationship: has_participant CCO:B0001920 ! Q6WZM0_HUMAN relationship: has_participant CCO:B0001940 ! CUZD1_HUMAN relationship: has_participant CCO:B0001980 ! DP13B_HUMAN relationship: has_participant CCO:B0002023 ! ARHG1_HUMAN relationship: has_participant CCO:B0002027 ! CUL5_HUMAN relationship: has_participant CCO:B0002039 ! SIPA1_HUMAN relationship: has_participant CCO:B0002054 ! UHRF2_HUMAN relationship: has_participant CCO:B0002063 ! UHRF1_HUMAN relationship: has_participant CCO:B0002080 ! KIF2C_HUMAN relationship: has_participant CCO:B0002120 ! PDGFD_HUMAN relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0002158 ! PDGFC_HUMAN relationship: has_participant CCO:B0002164 ! GKN1_HUMAN relationship: has_participant CCO:B0002165 ! KIF15_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0002219 ! DP13A_HUMAN relationship: has_participant CCO:B0002227 ! TPX2_HUMAN relationship: has_participant CCO:B0002233 ! CC14A_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0002250 ! NUDC_HUMAN relationship: has_participant CCO:B0005356 ! ANDR_HUMAN relationship: has_participant CCO:B0005378 ! S100B_HUMAN relationship: has_participant CCO:B0005424 ! EP15_HUMAN relationship: has_participant CCO:B0005438 ! MET_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005662 ! XPO2_HUMAN relationship: has_participant CCO:B0005808 ! THIO_HUMAN relationship: has_participant CCO:B0005809 ! RBBP7_HUMAN relationship: has_participant CCO:B0005833 ! EPHB4_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005870 ! TGFA_HUMAN relationship: has_participant CCO:B0005906 ! ERBB4_HUMAN relationship: has_participant CCO:B0005981 ! TRI27_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN relationship: has_participant CCO:B0006262 ! CD81_HUMAN relationship: has_participant CCO:B0006334 ! AMRP_HUMAN relationship: has_participant CCO:B0015400 ! MAD1_HUMAN relationship: has_participant CCO:B0016650 ! FCERB_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0017123 ! PROK2_HUMAN relationship: has_participant CCO:B0018024 ! ZPR1_HUMAN relationship: has_participant CCO:B0018695 ! EDNRA_HUMAN relationship: has_participant CCO:B0019772 ! EPS8_HUMAN relationship: has_participant CCO:B0019963 ! TISD_HUMAN relationship: has_participant CCO:B0020040 ! A3RLL6_HUMAN relationship: has_participant CCO:B0020438 ! A6NNS1_HUMAN relationship: has_participant CCO:B0021138 ! PDXK_HUMAN relationship: has_participant CCO:B0022781 ! PIM1_HUMAN relationship: has_participant CCO:B0023418 ! STAT4_HUMAN relationship: has_participant CCO:B0023704 ! K1C16_HUMAN relationship: has_participant CCO:B0023793 ! FURIN_HUMAN relationship: has_participant CCO:B0024873 ! NR6A1_HUMAN relationship: has_participant CCO:B0025068 ! PDZD1_HUMAN relationship: has_participant CCO:B0025531 ! A2A2V4_HUMAN relationship: has_participant CCO:B0025953 ! LRP1_HUMAN relationship: has_participant CCO:B0026247 ! A2NWD3_HUMAN relationship: has_participant CCO:B0026249 ! ZMY11_HUMAN relationship: has_participant CCO:B0026257 ! PDS5B_HUMAN relationship: has_participant CCO:B0026258 ! TCF19_HUMAN relationship: has_participant CCO:B0026622 ! A8MTK9_HUMAN relationship: has_participant CCO:B0026670 ! TICN1_HUMAN relationship: has_participant CCO:B0028029 ! GO45_HUMAN relationship: has_participant CCO:B0030266 ! GNAT1_HUMAN relationship: has_participant CCO:B0033001 ! RS27_HUMAN relationship: has_participant CCO:B0033704 ! FRIH_HUMAN relationship: has_participant CCO:B0034258 ! GAS6_HUMAN relationship: has_participant CCO:B0035955 ! CXCL7_HUMAN relationship: has_participant CCO:B0036431 ! SPHK2_HUMAN relationship: has_participant CCO:B0036567 ! IF5A1_HUMAN relationship: has_participant CCO:B0036577 ! IF5A2_HUMAN relationship: has_participant CCO:B0037751 ! BGH3_HUMAN relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN relationship: has_participant CCO:B0038265 ! ADA1D_HUMAN relationship: has_participant CCO:B0038878 ! CSF1_HUMAN relationship: has_participant CCO:B0040082 ! UBP8_HUMAN relationship: has_participant CCO:B0040520 ! A9UJN9_HUMAN relationship: has_participant CCO:B0041257 ! E4F1_HUMAN relationship: has_participant CCO:B0041668 ! GROA_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: has_participant CCO:B0048870 ! CRIP1_HUMAN relationship: has_participant CCO:B0049558 ! HG2A_HUMAN relationship: has_participant CCO:B0049672 ! TPO_HUMAN relationship: has_participant CCO:B0049674 ! Q5FBX8_HUMAN relationship: has_participant CCO:B0050818 ! WIT1_HUMAN relationship: has_participant CCO:B0054337 ! CYR61_HUMAN relationship: has_participant CCO:B0054410 ! MYT2_HUMAN relationship: has_participant CCO:B0054412 ! PSPHL_HUMAN relationship: has_participant CCO:B0054440 ! INSI1_HUMAN relationship: has_participant CCO:B0054497 ! RCL_HUMAN relationship: has_participant CCO:B0054526 ! NRDC_HUMAN relationship: has_participant CCO:B0054601 ! MTG16_HUMAN relationship: has_participant CCO:B0054641 ! FRAT2_HUMAN relationship: has_participant CCO:B0054643 ! GPC4_HUMAN relationship: has_participant CCO:B0054660 ! CREG1_HUMAN relationship: has_participant CCO:B0054719 ! UBR5_HUMAN relationship: has_participant CCO:B0054757 ! RPGF3_HUMAN relationship: has_participant CCO:B0054784 ! LY86_HUMAN relationship: has_participant CCO:B0054810 ! LGI1_HUMAN relationship: has_participant CCO:B0054811 ! BY55_HUMAN relationship: has_participant CCO:B0054842 ! PRL_HUMAN relationship: has_participant CCO:B0054848 ! GLUC_HUMAN relationship: has_participant CCO:B0054851 ! NPY_HUMAN relationship: has_participant CCO:B0054888 ! MAS_HUMAN relationship: has_participant CCO:B0054901 ! CD5_HUMAN relationship: has_participant CCO:B0054911 ! FES_HUMAN relationship: has_participant CCO:B0054912 ! CSF1R_HUMAN relationship: has_participant CCO:B0054924 ! ACM4_HUMAN relationship: has_participant CCO:B0054933 ! IL6RA_HUMAN relationship: has_participant CCO:B0054936 ! ACM5_HUMAN relationship: has_participant CCO:B0054950 ! TACD2_HUMAN relationship: has_participant CCO:B0054965 ! GLI2_HUMAN relationship: has_participant CCO:B0054969 ! PYY_HUMAN relationship: has_participant CCO:B0054986 ! ACM1_HUMAN relationship: has_participant CCO:B0054991 ! ERG_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055021 ! MIF_HUMAN relationship: has_participant CCO:B0055022 ! IRF2_HUMAN relationship: has_participant CCO:B0055038 ! ELN_HUMAN relationship: has_participant CCO:B0055039 ! AREG_HUMAN relationship: has_participant CCO:B0055090 ! TAL1_HUMAN relationship: has_participant CCO:B0055115 ! ACM3_HUMAN relationship: has_participant CCO:B0055135 ! SCF_HUMAN relationship: has_participant CCO:B0055143 ! ACES_HUMAN relationship: has_participant CCO:B0055149 ! IBP4_HUMAN relationship: has_participant CCO:B0055185 ! MT3_HUMAN relationship: has_participant CCO:B0055186 ! RBTN1_HUMAN relationship: has_participant CCO:B0055220 ! TSPO_HUMAN relationship: has_participant CCO:B0055222 ! GRPR_HUMAN relationship: has_participant CCO:B0055252 ! GASR_HUMAN relationship: has_participant CCO:B0055262 ! CD70_HUMAN relationship: has_participant CCO:B0055263 ! TNFL8_HUMAN relationship: has_participant CCO:B0055315 ! PEDF_HUMAN relationship: has_participant CCO:B0055317 ! ZEB1_HUMAN relationship: has_participant CCO:B0055326 ! TXLNA_HUMAN relationship: has_participant CCO:B0055327 ! TPOR_HUMAN relationship: has_participant CCO:B0055340 ! TNFL9_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0055401 ! REG1B_HUMAN relationship: has_participant CCO:B0055484 ! HDGF_HUMAN relationship: has_participant CCO:B0055519 ! EMP1_HUMAN relationship: has_participant CCO:B0055520 ! EMP2_HUMAN relationship: has_participant CCO:B0055589 ! GBG2_HUMAN relationship: has_participant CCO:B0055668 ! DAB2_HUMAN relationship: has_participant CCO:B0055671 ! LRP2_HUMAN relationship: has_participant CCO:B0055681 ! NDP_HUMAN relationship: has_participant CCO:B0055686 ! IL9R_HUMAN relationship: has_participant CCO:B0055688 ! IL5RA_HUMAN relationship: has_participant CCO:B0055689 ! TSPY1_HUMAN relationship: has_participant CCO:B0055696 ! CO4A3_HUMAN relationship: has_participant CCO:B0055707 ! TNR17_HUMAN relationship: has_participant CCO:B0055722 ! PPARD_HUMAN relationship: has_participant CCO:B0055766 ! REG3A_HUMAN relationship: has_participant CCO:B0055775 ! PRDX1_HUMAN relationship: has_participant CCO:B0055781 ! AMPE_HUMAN relationship: has_participant CCO:B0055836 ! BST2_HUMAN relationship: has_participant CCO:B0055850 ! Q12845_HUMAN relationship: has_participant CCO:B0055875 ! KLF10_HUMAN relationship: has_participant CCO:B0055891 ! I15RA_HUMAN relationship: has_participant CCO:B0055907 ! ILK_HUMAN relationship: has_participant CCO:B0055908 ! HAP28_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN relationship: has_participant CCO:B0055990 ! S29A2_HUMAN relationship: has_participant CCO:B0056005 ! Q14632_HUMAN relationship: has_participant CCO:B0056006 ! INSL4_HUMAN relationship: has_participant CCO:B0056068 ! STIL_HUMAN relationship: has_participant CCO:B0056102 ! NAB2_HUMAN relationship: has_participant CCO:B0056143 ! CSRP2_HUMAN relationship: has_participant CCO:B0056160 ! CTF1_HUMAN relationship: has_participant CCO:B0056170 ! FSCN1_HUMAN relationship: has_participant CCO:B0056172 ! IF16_HUMAN relationship: has_participant CCO:B0056175 ! MIA_HUMAN relationship: has_participant CCO:B0056179 ! TRXR1_HUMAN relationship: has_participant CCO:B0056685 ! CD276_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: has_participant CCO:B0057945 ! CGAT1_HUMAN relationship: has_participant CCO:B0058115 ! PRG4_HUMAN relationship: has_participant CCO:B0058136 ! IGSF8_HUMAN relationship: has_participant CCO:B0058159 ! ISG20_HUMAN relationship: has_participant CCO:B0058335 ! NOX5_HUMAN relationship: has_participant CCO:B0058434 ! OSMR_HUMAN relationship: has_participant CCO:B0058474 ! RETNB_HUMAN relationship: has_participant CCO:B0058532 ! TRAIP_HUMAN relationship: has_participant CCO:B0058621 ! BHLH3_HUMAN relationship: has_participant CCO:B0058705 ! TXND1_HUMAN relationship: has_participant CCO:B0058756 ! NANOG_HUMAN relationship: has_participant CCO:B0058823 ! SRA1_HUMAN relationship: has_participant CCO:B0058851 ! FZD3_HUMAN relationship: has_participant CCO:B0058906 ! DUS22_HUMAN relationship: has_participant CCO:B0058991 ! EHF_HUMAN relationship: has_participant CCO:B0059011 ! PD1L1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059077 ! PEMT_HUMAN relationship: has_participant CCO:B0059082 ! CKLF_HUMAN relationship: has_participant CCO:B0059110 ! VTI1B_HUMAN relationship: has_participant CCO:B0059197 ! PRDM4_HUMAN relationship: has_participant CCO:B0059208 ! ELF5_HUMAN relationship: has_participant CCO:B0059209 ! CDV3_HUMAN relationship: has_participant CCO:B0059210 ! CB029_HUMAN relationship: has_participant CCO:B0059286 ! LAMP3_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN relationship: has_participant CCO:B0059336 ! HDGR3_HUMAN relationship: has_participant CCO:B0059400 ! MORF4_HUMAN [Term] id: CCO:P0000816 name: positive regulation of cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators] subset: gosubset_prok synonym: "activation of cell proliferation" NARROW [] synonym: "stimulation of cell proliferation" NARROW [] synonym: "up regulation of cell proliferation" EXACT [] synonym: "up-regulation of cell proliferation" EXACT [] synonym: "upregulation of cell proliferation" EXACT [] xref: GO:0008284 is_a: CCO:P0002045 ! regulation of cell proliferation is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001402 ! VEGFD_HUMAN relationship: has_participant CCO:B0001418 ! DNJA2_HUMAN relationship: has_participant CCO:B0001435 ! CD123_HUMAN relationship: has_participant CCO:B0001442 ! RECQ4_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001500 ! FGF4_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001522 ! FOSL1_HUMAN relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0001541 ! PTN_HUMAN relationship: has_participant CCO:B0001545 ! FGF7_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001569 ! SHC1_HUMAN relationship: has_participant CCO:B0001573 ! CCND2_HUMAN relationship: has_participant CCO:B0001577 ! MPIP2_HUMAN relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0001587 ! TTK_HUMAN relationship: has_participant CCO:B0001590 ! BTC_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001612 ! MATK_HUMAN relationship: has_participant CCO:B0001623 ! NOL1_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001633 ! PLGF_HUMAN relationship: has_participant CCO:B0001634 ! VEGFB_HUMAN relationship: has_participant CCO:B0001635 ! VEGFC_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001683 ! PROK1_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001704 ! RHOG_HUMAN relationship: has_participant CCO:B0001761 ! CUL3_HUMAN relationship: has_participant CCO:B0001771 ! CD2L5_HUMAN relationship: has_participant CCO:B0001862 ! SPDYA_HUMAN relationship: has_participant CCO:B0002030 ! TBRG4_HUMAN relationship: has_participant CCO:B0002037 ! DDX11_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: has_participant CCO:B0002164 ! GKN1_HUMAN relationship: has_participant CCO:B0002202 ! SRTD1_HUMAN relationship: has_participant CCO:B0002223 ! MCTS1_HUMAN relationship: has_participant CCO:B0005376 ! NP1L1_HUMAN relationship: has_participant CCO:B0005447 ! NRP1_HUMAN relationship: has_participant CCO:B0005451 ! HXC10_HUMAN relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0005542 ! TGFR2_HUMAN relationship: has_participant CCO:B0005719 ! VGFR1_HUMAN relationship: has_participant CCO:B0005821 ! K2C6A_HUMAN relationship: has_participant CCO:B0005846 ! FAK2_HUMAN relationship: has_participant CCO:B0006048 ! HSF4_HUMAN relationship: has_participant CCO:B0006088 ! CPNS1_HUMAN relationship: has_participant CCO:B0006163 ! SSRA_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN relationship: has_participant CCO:B0006262 ! CD81_HUMAN relationship: has_participant CCO:B0015134 ! GLP2R_HUMAN relationship: has_participant CCO:B0020370 ! TGFR1_HUMAN relationship: has_participant CCO:B0020505 ! PGFRA_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN relationship: has_participant CCO:B0022226 ! ID4_HUMAN relationship: has_participant CCO:B0022985 ! FGF17_HUMAN relationship: has_participant CCO:B0022986 ! FGF18_HUMAN relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0024472 ! BNC1_HUMAN relationship: has_participant CCO:B0025802 ! RAC2_HUMAN relationship: has_participant CCO:B0025951 ! LRP5_HUMAN relationship: has_participant CCO:B0026846 ! CNTFR_HUMAN relationship: has_participant CCO:B0034147 ! I12R2_HUMAN relationship: has_participant CCO:B0038265 ! ADA1D_HUMAN relationship: has_participant CCO:B0038878 ! CSF1_HUMAN relationship: has_participant CCO:B0039811 ! BIRC6_HUMAN relationship: has_participant CCO:B0041666 ! CXCL5_HUMAN relationship: has_participant CCO:B0041800 ! CAN1_HUMAN relationship: has_participant CCO:B0042120 ! NODAL_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0043825 ! RS15A_HUMAN relationship: has_participant CCO:B0048655 ! PO3F2_HUMAN relationship: has_participant CCO:B0048868 ! CRIP2_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN relationship: has_participant CCO:B0054413 ! BRAC_HUMAN relationship: has_participant CCO:B0054674 ! TNF13_HUMAN relationship: has_participant CCO:B0054691 ! CIAO1_HUMAN relationship: has_participant CCO:B0054727 ! S1PR2_HUMAN relationship: has_participant CCO:B0054776 ! STABP_HUMAN relationship: has_participant CCO:B0054777 ! NET1_HUMAN relationship: has_participant CCO:B0054783 ! FR1OP_HUMAN relationship: has_participant CCO:B0054793 ! TBCD8_HUMAN relationship: has_participant CCO:B0054831 ! TIMP1_HUMAN relationship: has_participant CCO:B0054849 ! VIP_HUMAN relationship: has_participant CCO:B0054853 ! IGF1A_HUMAN relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0054875 ! CXL10_HUMAN relationship: has_participant CCO:B0054885 ! CSF2_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054900 ! REG1A_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054922 ! GLI1_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0054934 ! 5HT1A_HUMAN relationship: has_participant CCO:B0054937 ! ADA2A_HUMAN relationship: has_participant CCO:B0054952 ! CSF3_HUMAN relationship: has_participant CCO:B0054977 ! KIT_HUMAN relationship: has_participant CCO:B0054980 ! CLUS_HUMAN relationship: has_participant CCO:B0054986 ! ACM1_HUMAN relationship: has_participant CCO:B0054997 ! DCOR_HUMAN relationship: has_participant CCO:B0054999 ! PTHR_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN relationship: has_participant CCO:B0055032 ! IL9_HUMAN relationship: has_participant CCO:B0055054 ! TSHR_HUMAN relationship: has_participant CCO:B0055097 ! LOX12_HUMAN relationship: has_participant CCO:B0055126 ! IL11_HUMAN relationship: has_participant CCO:B0055128 ! YYY3_HUMAN relationship: has_participant CCO:B0055160 ! TNFL4_HUMAN relationship: has_participant CCO:B0055168 ! PRTN3_HUMAN relationship: has_participant CCO:B0055176 ! CXCR2_HUMAN relationship: has_participant CCO:B0055198 ! 5HT2A_HUMAN relationship: has_participant CCO:B0055243 ! TLX1_HUMAN relationship: has_participant CCO:B0055252 ! GASR_HUMAN relationship: has_participant CCO:B0055253 ! VIPR1_HUMAN relationship: has_participant CCO:B0055286 ! ADML_HUMAN relationship: has_participant CCO:B0055304 ! VGFR3_HUMAN relationship: has_participant CCO:B0055310 ! ACHA7_HUMAN relationship: has_participant CCO:B0055332 ! IL15_HUMAN relationship: has_participant CCO:B0055346 ! CD86_HUMAN relationship: has_participant CCO:B0055354 ! I12R1_HUMAN relationship: has_participant CCO:B0055355 ! LIFR_HUMAN relationship: has_participant CCO:B0055366 ! NAMPT_HUMAN relationship: has_participant CCO:B0055419 ! PTH2R_HUMAN relationship: has_participant CCO:B0055423 ! DHYS_HUMAN relationship: has_participant CCO:B0055435 ! FLT3L_HUMAN relationship: has_participant CCO:B0055569 ! VSX2_HUMAN relationship: has_participant CCO:B0055679 ! PURA_HUMAN relationship: has_participant CCO:B0055739 ! RON_HUMAN relationship: has_participant CCO:B0055741 ! EGR4_HUMAN relationship: has_participant CCO:B0055793 ! CD47_HUMAN relationship: has_participant CCO:B0055864 ! TSN31_HUMAN relationship: has_participant CCO:B0055883 ! Q13169_HUMAN relationship: has_participant CCO:B0055886 ! TBX2_HUMAN relationship: has_participant CCO:B0055894 ! SLAF1_HUMAN relationship: has_participant CCO:B0055907 ! ILK_HUMAN relationship: has_participant CCO:B0055916 ! VPP3_HUMAN relationship: has_participant CCO:B0055950 ! KLF5_HUMAN relationship: has_participant CCO:B0055986 ! HES1_HUMAN relationship: has_participant CCO:B0056004 ! IHH_HUMAN relationship: has_participant CCO:B0056036 ! SUZ12_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056160 ! CTF1_HUMAN relationship: has_participant CCO:B0056164 ! CCL14_HUMAN relationship: has_participant CCO:B0056178 ! DDR2_HUMAN relationship: has_participant CCO:B0057447 ! OSR2_HUMAN relationship: has_participant CCO:B0058132 ! CS010_HUMAN relationship: has_participant CCO:B0058418 ! S1PR3_HUMAN relationship: has_participant CCO:B0058631 ! DERL2_HUMAN relationship: has_participant CCO:B0058785 ! DEFM_HUMAN relationship: has_participant CCO:B0059045 ! SIRPG_HUMAN relationship: has_participant CCO:B0059291 ! CLC11_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN relationship: has_participant CCO:B0059386 ! NOX1_HUMAN relationship: has_participant CCO:B0059413 ! TNR11_HUMAN relationship: positively_regulates CCO:P0000815 ! cell proliferation [Term] id: CCO:P0000817 name: negative regulation of cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] synonym: "down regulation of cell proliferation" EXACT [] synonym: "down-regulation of cell proliferation" EXACT [] synonym: "downregulation of cell proliferation" EXACT [] synonym: "inhibition of cell proliferation" NARROW [] xref: GO:0008285 is_a: CCO:P0002045 ! regulation of cell proliferation is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0001359 ! CHK1_HUMAN relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001371 ! LX15B_HUMAN relationship: has_participant CCO:B0001372 ! PPM1D_HUMAN relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0001414 ! JAK2_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001475 ! IL1A_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001504 ! IL8_HUMAN relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0001517 ! IFM1_HUMAN relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0001535 ! E2AK2_HUMAN relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0001593 ! PGH2_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001606 ! CSK_HUMAN relationship: has_participant CCO:B0001613 ! FRK_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001672 ! GAS1_HUMAN relationship: has_participant CCO:B0001673 ! AIF1_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001679 ! HDAC4_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001706 ! FOXO4_HUMAN relationship: has_participant CCO:B0001712 ! MDM2_HUMAN relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0001727 ! RBBP4_HUMAN relationship: has_participant CCO:B0001732 ! SNF5_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0001760 ! CUL2_HUMAN relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0001768 ! Q13876_HUMAN relationship: has_participant CCO:B0001774 ! TOB2_HUMAN relationship: has_participant CCO:B0001778 ! BTG3_HUMAN relationship: has_participant CCO:B0001803 ! CDK10_HUMAN relationship: has_participant CCO:B0001823 ! CDKN3_HUMAN relationship: has_participant CCO:B0001832 ! TBRG1_HUMAN relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0002027 ! CUL5_HUMAN relationship: has_participant CCO:B0002033 ! PINX1_HUMAN relationship: has_participant CCO:B0002064 ! GML_HUMAN relationship: has_participant CCO:B0002074 ! MNT_HUMAN relationship: has_participant CCO:B0002075 ! NECD_HUMAN relationship: has_participant CCO:B0002081 ! CGRE1_HUMAN relationship: has_participant CCO:B0002082 ! CGRF1_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002114 ! Q9BYG9_HUMAN relationship: has_participant CCO:B0002116 ! NOG1_HUMAN relationship: has_participant CCO:B0002174 ! BTG4_HUMAN relationship: has_participant CCO:B0002189 ! DEC1_HUMAN relationship: has_participant CCO:B0002217 ! ING1_HUMAN relationship: has_participant CCO:B0002234 ! ING4_HUMAN relationship: has_participant CCO:B0002247 ! DLEC1_HUMAN relationship: has_participant CCO:B0002266 ! SESN1_HUMAN relationship: has_participant CCO:B0002267 ! MYO16_HUMAN relationship: has_participant CCO:B0005202 ! LDOC1_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005284 ! ING5_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005646 ! FGFP1_HUMAN relationship: has_participant CCO:B0005674 ! E2AK1_HUMAN relationship: has_participant CCO:B0005703 ! ABI1_HUMAN relationship: has_participant CCO:B0005825 ! S10AB_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN relationship: has_participant CCO:B0006010 ! TNR8_HUMAN relationship: has_participant CCO:B0015398 ! MXI1_HUMAN relationship: has_participant CCO:B0015399 ! MAD4_HUMAN relationship: has_participant CCO:B0015956 ! IFNK_HUMAN relationship: has_participant CCO:B0015966 ! IFNB_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0017844 ! TGFI1_HUMAN relationship: has_participant CCO:B0019651 ! ATS8_HUMAN relationship: has_participant CCO:B0019689 ! ATS1_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0021721 ! CTBP1_HUMAN relationship: has_participant CCO:B0021723 ! CTBP2_HUMAN relationship: has_participant CCO:B0021811 ! SYWC_HUMAN relationship: has_participant CCO:B0023306 ! DLG3_HUMAN relationship: has_participant CCO:B0025823 ! TOB1_HUMAN relationship: has_participant CCO:B0026257 ! PDS5B_HUMAN relationship: has_participant CCO:B0028314 ! TIG3_HUMAN relationship: has_participant CCO:B0030313 ! ETS1_HUMAN relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0033689 ! Q8TD27_HUMAN relationship: has_participant CCO:B0033704 ! FRIH_HUMAN relationship: has_participant CCO:B0034060 ! FABP7_HUMAN relationship: has_participant CCO:B0034070 ! FABPH_HUMAN relationship: has_participant CCO:B0034126 ! RARG_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0036934 ! HNF4A_HUMAN relationship: has_participant CCO:B0038258 ! ADA1A_HUMAN relationship: has_participant CCO:B0041668 ! GROA_HUMAN relationship: has_participant CCO:B0041672 ! BNIPL_HUMAN relationship: has_participant CCO:B0043520 ! CXA1_HUMAN relationship: has_participant CCO:B0048652 ! PIT1_HUMAN relationship: has_participant CCO:B0050534 ! CNOT8_HUMAN relationship: has_participant CCO:B0050755 ! SSR2_HUMAN relationship: has_participant CCO:B0050785 ! SSR5_HUMAN relationship: has_participant CCO:B0050788 ! SSR1_HUMAN relationship: has_participant CCO:B0050793 ! SSR4_HUMAN relationship: has_participant CCO:B0050794 ! SSR3_HUMAN relationship: has_participant CCO:B0051620 ! ADSV_HUMAN relationship: has_participant CCO:B0054344 ! LPP1_HUMAN relationship: has_participant CCO:B0054348 ! BAI1_HUMAN relationship: has_participant CCO:B0054366 ! P5I11_HUMAN relationship: has_participant CCO:B0054387 ! KLF11_HUMAN relationship: has_participant CCO:B0054472 ! MCA3_HUMAN relationship: has_participant CCO:B0054480 ! P52K_HUMAN relationship: has_participant CCO:B0054483 ! KLF4_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0054650 ! SKAP2_HUMAN relationship: has_participant CCO:B0054651 ! PRKRA_HUMAN relationship: has_participant CCO:B0054662 ! UTP20_HUMAN relationship: has_participant CCO:B0054756 ! GDF11_HUMAN relationship: has_participant CCO:B0054764 ! CXB6_HUMAN relationship: has_participant CCO:B0054795 ! CER1_HUMAN relationship: has_participant CCO:B0054817 ! GAS8_HUMAN relationship: has_participant CCO:B0054826 ! PLMN_HUMAN relationship: has_participant CCO:B0054835 ! GON1_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054917 ! UROM_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0054999 ! PTHR_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055034 ! B4GT1_HUMAN relationship: has_participant CCO:B0055046 ! TIMP2_HUMAN relationship: has_participant CCO:B0055058 ! CL3L1_HUMAN relationship: has_participant CCO:B0055113 ! CD33_HUMAN relationship: has_participant CCO:B0055148 ! GALA_HUMAN relationship: has_participant CCO:B0055173 ! IBP6_HUMAN relationship: has_participant CCO:B0055183 ! ZA2G_HUMAN relationship: has_participant CCO:B0055322 ! COIA1_HUMAN relationship: has_participant CCO:B0055400 ! T4S4_HUMAN relationship: has_participant CCO:B0055419 ! PTH2R_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN relationship: has_participant CCO:B0055437 ! TIG1_HUMAN relationship: has_participant CCO:B0055461 ! FABP6_HUMAN relationship: has_participant CCO:B0055507 ! LBX1_HUMAN relationship: has_participant CCO:B0055521 ! EMP3_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0055537 ! CCL23_HUMAN relationship: has_participant CCO:B0055569 ! VSX2_HUMAN relationship: has_participant CCO:B0055607 ! SMS_HUMAN relationship: has_participant CCO:B0055615 ! BTG1_HUMAN relationship: has_participant CCO:B0055649 ! BTG2_HUMAN relationship: has_participant CCO:B0055696 ! CO4A3_HUMAN relationship: has_participant CCO:B0055738 ! MUC24_HUMAN relationship: has_participant CCO:B0055780 ! TNR9_HUMAN relationship: has_participant CCO:B0055875 ! KLF10_HUMAN relationship: has_participant CCO:B0056027 ! GPNMB_HUMAN relationship: has_participant CCO:B0056109 ! SPEG_HUMAN relationship: has_participant CCO:B0056114 ! SMAD1_HUMAN relationship: has_participant CCO:B0056131 ! IBP7_HUMAN relationship: has_participant CCO:B0056240 ! P3H1_HUMAN relationship: has_participant CCO:B0056690 ! TENC1_HUMAN relationship: has_participant CCO:B0056953 ! ENPP7_HUMAN relationship: has_participant CCO:B0057317 ! IL29_HUMAN relationship: has_participant CCO:B0057318 ! I28RA_HUMAN relationship: has_participant CCO:B0058063 ! BAP1_HUMAN relationship: has_participant CCO:B0058095 ! PROX1_HUMAN relationship: has_participant CCO:B0058129 ! KISSR_HUMAN relationship: has_participant CCO:B0058147 ! RERG_HUMAN relationship: has_participant CCO:B0058234 ! PAWR_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN relationship: has_participant CCO:B0058831 ! Q9NP35_HUMAN relationship: has_participant CCO:B0058854 ! NOX4_HUMAN relationship: has_participant CCO:B0058883 ! Q9NR26_HUMAN relationship: has_participant CCO:B0058925 ! AT8A2_HUMAN relationship: has_participant CCO:B0059045 ! SIRPG_HUMAN relationship: has_participant CCO:B0059187 ! Q9UK67_HUMAN relationship: has_participant CCO:B0059211 ! TEN1_HUMAN relationship: has_participant CCO:B0059264 ! TRI35_HUMAN relationship: negatively_regulates CCO:P0000815 ! cell proliferation [Term] id: CCO:P0000818 name: insulin receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of the insulin receptor binding to insulin." [GOC:ceb] synonym: "daf-2 receptor signaling pathway" NARROW [] synonym: "insulin receptor signalling pathway" EXACT [] xref: GO:0008286 xref: Reactome:211690 xref: Reactome:221461 xref: Reactome:230089 xref: Reactome:238112 xref: Reactome:244710 xref: Reactome:249874 xref: Reactome:252635 xref: Reactome:255820 xref: Reactome:259220 xref: Reactome:262576 xref: Reactome:265392 xref: Reactome:268531 xref: Reactome:274256 xref: Reactome:280719 xref: Reactome:282926 xref: Reactome:286743 xref: Reactome:288405 xref: Reactome:74752 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0001472 ! IGF2_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001706 ! FOXO4_HUMAN relationship: has_participant CCO:B0005454 ! GRB2_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005641 ! SRBS1_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005873 ! SN1L2_HUMAN relationship: has_participant CCO:B0006233 ! PDPK1_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0016881 ! FOXO1_HUMAN relationship: has_participant CCO:B0026600 ! P55G_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0051810 ! IRS1_HUMAN relationship: has_participant CCO:B0054343 ! SH2B2_HUMAN relationship: has_participant CCO:B0055096 ! PTN1_HUMAN relationship: has_participant CCO:B0055897 ! GRB10_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN relationship: has_participant CCO:B0055928 ! 4EBP2_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0058005 ! PHIP_HUMAN relationship: has_participant CCO:B0058066 ! AP3S1_HUMAN relationship: has_participant CCO:B0058692 ! ZF106_HUMAN relationship: has_participant CCO:B0059278 ! BAIP2_HUMAN [Term] id: CCO:P0000819 name: torso signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of the torso transmembrane receptor tyrosine kinase binding to its physiological ligand." [GOC:go_curators] synonym: "torso signalling pathway" EXACT [] xref: GO:0008293 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:P0000820 name: gurken receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to the ligand Gurken." [GOC:bf] synonym: "gurken receptor signalling pathway" EXACT [] xref: GO:0008314 is_a: CCO:P0000715 ! epidermal growth factor receptor signaling pathway [Term] id: CCO:P0000821 name: asymmetric cell division namespace: biological_process def: "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] synonym: "asymmetric cytokinesis" RELATED [] synonym: "asymmetrical cell division" EXACT [] synonym: "asymmetrical cytokinesis" RELATED [] xref: GO:0008356 is_a: CCO:P0003077 ! cell division relationship: has_participant CCO:B0001996 ! PARD3_HUMAN [Term] id: CCO:P0000822 name: regulation of cell shape namespace: biological_process def: "Any process that modulates the surface configuration of a cell." [GOC:dph, GOC:go_curators, GOC:tb] subset: gosubset_prok xref: GO:0008360 xref: GO:0045788 xref: GO:0045789 is_a: CCO:P0001241 ! regulation of cell morphogenesis relationship: has_participant CCO:B0001401 ! GAS2_HUMAN relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN relationship: has_participant CCO:B0005971 ! MYH14_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0018212 ! EZRI_HUMAN relationship: has_participant CCO:B0019193 ! MYH9_HUMAN relationship: has_participant CCO:B0019194 ! MYH10_HUMAN relationship: has_participant CCO:B0019513 ! TAOK2_HUMAN relationship: has_participant CCO:B0024597 ! CEND3_HUMAN relationship: has_participant CCO:B0031065 ! FBLI1_HUMAN relationship: has_participant CCO:B0033122 ! ITB2_HUMAN relationship: has_participant CCO:B0034023 ! S26A5_HUMAN relationship: has_participant CCO:B0037573 ! CYFP1_HUMAN relationship: has_participant CCO:B0054248 ! B1ALY0_HUMAN relationship: has_participant CCO:B0054322 ! LST1_HUMAN relationship: has_participant CCO:B0054357 ! BORG1_HUMAN relationship: has_participant CCO:B0054544 ! AT10A_HUMAN relationship: has_participant CCO:B0054665 ! PALM_HUMAN relationship: has_participant CCO:B0055051 ! EPB42_HUMAN relationship: has_participant CCO:B0055081 ! RHOQ_HUMAN relationship: has_participant CCO:B0055676 ! FGD1_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN relationship: has_participant CCO:B0055939 ! ITA7_HUMAN relationship: has_participant CCO:B0056480 ! FGD3_HUMAN relationship: has_participant CCO:B0056874 ! BORG3_HUMAN relationship: has_participant CCO:B0057029 ! FGD5_HUMAN relationship: has_participant CCO:B0057083 ! FGD6_HUMAN relationship: has_participant CCO:B0057198 ! FGD2_HUMAN relationship: has_participant CCO:B0057306 ! PDPN_HUMAN relationship: has_participant CCO:B0057380 ! PALM2_HUMAN relationship: has_participant CCO:B0057967 ! SHRM3_HUMAN relationship: has_participant CCO:B0058150 ! FERM2_HUMAN relationship: has_participant CCO:B0058282 ! FGD4_HUMAN relationship: has_participant CCO:B0058708 ! BORG4_HUMAN relationship: has_participant CCO:B0058716 ! RHOJ_HUMAN relationship: has_participant CCO:B0058837 ! PALMD_HUMAN relationship: has_participant CCO:B0058903 ! C42S2_HUMAN relationship: has_participant CCO:B0058904 ! C42S1_HUMAN relationship: has_participant CCO:B0059107 ! CFDP1_HUMAN relationship: has_participant CCO:B0059193 ! BORG2_HUMAN [Term] id: CCO:P0000823 name: fibroblast growth factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands." [GOC:ceb] synonym: "FGF receptor signaling pathway" EXACT [] synonym: "FGF receptor signalling pathway" EXACT [] synonym: "FGFR signaling pathway" EXACT [] synonym: "fibroblast growth factor receptor signalling pathway" EXACT [] xref: GO:0008543 xref: Reactome:190236 xref: Reactome:190239 xref: Reactome:190241 xref: Reactome:190242 xref: Reactome:190322 xref: Reactome:190370 xref: Reactome:190371 xref: Reactome:190372 xref: Reactome:190373 xref: Reactome:190374 xref: Reactome:190375 xref: Reactome:190376 xref: Reactome:190377 xref: Reactome:211682 xref: Reactome:211683 xref: Reactome:211684 xref: Reactome:211685 xref: Reactome:211686 xref: Reactome:211687 xref: Reactome:211688 xref: Reactome:211689 xref: Reactome:212006 xref: Reactome:212007 xref: Reactome:212008 xref: Reactome:212009 xref: Reactome:212098 xref: Reactome:221453 xref: Reactome:221454 xref: Reactome:221455 xref: Reactome:221456 xref: Reactome:221457 xref: Reactome:221458 xref: Reactome:221459 xref: Reactome:221460 xref: Reactome:221770 xref: Reactome:221771 xref: Reactome:221772 xref: Reactome:221773 xref: Reactome:221857 xref: Reactome:230082 xref: Reactome:230083 xref: Reactome:230084 xref: Reactome:230085 xref: Reactome:230086 xref: Reactome:230087 xref: Reactome:230088 xref: Reactome:230349 xref: Reactome:230350 xref: Reactome:230351 xref: Reactome:230429 xref: Reactome:230445 xref: Reactome:238105 xref: Reactome:238106 xref: Reactome:238107 xref: Reactome:238108 xref: Reactome:238109 xref: Reactome:238110 xref: Reactome:238111 xref: Reactome:238387 xref: Reactome:238388 xref: Reactome:238389 xref: Reactome:238468 xref: Reactome:238485 xref: Reactome:249626 xref: Reactome:249627 xref: Reactome:249823 xref: Reactome:249824 xref: Reactome:249893 xref: Reactome:249913 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0001486 ! FGF1_HUMAN relationship: has_participant CCO:B0001500 ! FGF4_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001509 ! FGF6_HUMAN relationship: has_participant CCO:B0001511 ! FGF3_HUMAN relationship: has_participant CCO:B0001514 ! FGF5_HUMAN relationship: has_participant CCO:B0001545 ! FGF7_HUMAN relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0001674 ! FGF8_HUMAN relationship: has_participant CCO:B0005381 ! FGFR2_HUMAN relationship: has_participant CCO:B0005650 ! SHOC2_HUMAN relationship: has_participant CCO:B0005868 ! FGFR1_HUMAN relationship: has_participant CCO:B0005920 ! FGFR3_HUMAN relationship: has_participant CCO:B0017509 ! FGF20_HUMAN relationship: has_participant CCO:B0017511 ! FGF22_HUMAN relationship: has_participant CCO:B0017671 ! FGF16_HUMAN relationship: has_participant CCO:B0021696 ! CTGF_HUMAN relationship: has_participant CCO:B0022985 ! FGF17_HUMAN relationship: has_participant CCO:B0022986 ! FGF18_HUMAN relationship: has_participant CCO:B0051370 ! FIBP_HUMAN relationship: has_participant CCO:B0054491 ! FRS3_HUMAN relationship: has_participant CCO:B0055147 ! FGFR4_HUMAN relationship: has_participant CCO:B0057294 ! CEP57_HUMAN relationship: has_participant CCO:B0057975 ! FRS2_HUMAN relationship: has_participant CCO:B0058640 ! FGF23_HUMAN relationship: has_participant CCO:B0059103 ! Q9UDF1_HUMAN relationship: has_participant CCO:B0059108 ! KLOT_HUMAN [Term] id: CCO:P0000824 name: regulation of synaptic growth at neuromuscular junction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions." [GOC:go_curators] xref: GO:0008582 is_a: CCO:P0003166 ! regulation of synaptogenesis [Term] id: CCO:P0000825 name: release of cytoplasmic sequestered NF-kappaB namespace: biological_process def: "The release of NF-kappaB from specific molecules in the cytoplasm to which it was bound, thereby allowing its translocation into the nucleus." [GOC:jl] synonym: "activation of NF-kappa B" RELATED [] synonym: "negative regulation of cytoplasmic NF-kappaB retention" RELATED [] synonym: "negative regulation of cytoplasmic NF-kappaB sequestering" RELATED [] synonym: "negative regulation of cytoplasmic NF-kappaB sequestration" RELATED [] synonym: "negative regulation of cytoplasmic NF-kappaB storage" RELATED [] synonym: "release of NF-kappaB sequestered in cytoplasm" EXACT [] synonym: "release of NF-kappaB stored in cytoplasm" EXACT [] xref: GO:0008588 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN relationship: has_participant CCO:B0055574 ! NAL12_HUMAN relationship: part_of CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:P0000826 name: regulation of smoothened signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smoothened signaling." [GOC:go_curators] synonym: "regulation of smoothened activity" RELATED [] synonym: "regulation of smoothened by patched" RELATED [] synonym: "regulation of smoothened receptor activity by patched" RELATED [] synonym: "regulation of smoothened signalling pathway" EXACT [] xref: GO:0007226 xref: GO:0008589 xref: GO:0043109 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0001765 ! PTC1_HUMAN relationship: has_participant CCO:B0024799 ! ZIC1_HUMAN relationship: has_participant CCO:B0054922 ! GLI1_HUMAN relationship: has_participant CCO:B0055255 ! OTX2_HUMAN relationship: regulates CCO:P0000758 ! smoothened signaling pathway [Term] id: CCO:P0000827 name: regulation of Wnt receptor signaling pathway, calcium modulating pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of frizzled-2 signaling pathway" EXACT [] synonym: "regulation of frizzled-2 signalling pathway" EXACT [] xref: GO:0008591 is_a: CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: regulates CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway [Term] id: CCO:P0000828 name: regulation of Toll signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the Tl signaling pathway." [GOC:go_curators] synonym: "regulation of Tl signaling pathway" EXACT [] synonym: "regulation of Tl signalling pathway" EXACT [] synonym: "regulation of Toll signalling pathway" EXACT [] xref: GO:0008592 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0000810 ! Toll signaling pathway [Term] id: CCO:P0000829 name: regulation of Notch signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the Notch signaling pathway." [GOC:go_curators] synonym: "regulation of N signaling pathway" EXACT [] synonym: "regulation of N signalling pathway" EXACT [] synonym: "regulation of Notch signalling pathway" EXACT [] xref: GO:0008593 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0057298 ! DTX1_HUMAN relationship: regulates CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:P0000830 name: attachment of spindle microtubules to kinetochore namespace: biological_process def: "The process by which spindle microtubules become physically associated with the proteins making up the kinetochore complex." [GOC:vw, PMID:10322137] synonym: "amphotelic attachment" RELATED [] synonym: "bipolar attachment" RELATED [] synonym: "correction of merotelic attachment" NARROW [] synonym: "kinetochore microtubule interaction" BROAD [] synonym: "kinetochore-microtubule interaction" BROAD [] synonym: "microtubule anchoring at kinetochore" EXACT [] synonym: "microtubule and kinetochore interaction" RELATED [] synonym: "microtubule capture" NARROW [] synonym: "prevention of merotelic attachment" NARROW [] synonym: "spindle kinetochore attachment" EXACT [] xref: GO:0008608 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0000831 name: induction of apoptosis by extracellular signals namespace: biological_process def: "Any process induced by extracellular signals that directly activates any of the steps required for cell death by apoptosis." [GOC:ai] xref: GO:0008624 xref: Reactome:109607 xref: Reactome:208328 xref: Reactome:211795 xref: Reactome:212051 xref: Reactome:212052 xref: Reactome:217900 xref: Reactome:221559 xref: Reactome:221814 xref: Reactome:221815 xref: Reactome:226653 xref: Reactome:230167 xref: Reactome:230385 xref: Reactome:230386 xref: Reactome:73887 xref: Reactome:75157 xref: Reactome:75244 is_a: CCO:P0000672 ! induction of apoptosis relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005577 ! M3K5_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN relationship: has_participant CCO:B0035939 ! C8AP2_HUMAN relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0054618 ! PDCD6_HUMAN relationship: has_participant CCO:B0054901 ! CD5_HUMAN relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055207 ! CD38_HUMAN relationship: has_participant CCO:B0055221 ! AA1R_HUMAN relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0055463 ! DAP1_HUMAN relationship: has_participant CCO:B0055464 ! RT29_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0055976 ! FASTK_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0056020 ! Q14867_HUMAN relationship: has_participant CCO:B0058094 ! REQU_HUMAN relationship: has_participant CCO:B0058106 ! CASPA_HUMAN relationship: has_participant CCO:B0058121 ! TNR25_HUMAN relationship: has_participant CCO:B0058421 ! SORT_HUMAN relationship: has_participant CCO:B0059028 ! NDUAD_HUMAN relationship: has_participant CCO:B0059370 ! RIPK3_HUMAN [Term] id: CCO:P0000832 name: induction of apoptosis via death domain receptors namespace: biological_process xref: GO:0008625 is_a: CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0035939 ! C8AP2_HUMAN relationship: has_participant CCO:B0043604 ! DEDD_HUMAN relationship: has_participant CCO:B0043605 ! DEDD2_HUMAN relationship: has_participant CCO:B0054301 ! TR10A_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:P0000833 name: induction of apoptosis by granzyme namespace: biological_process xref: GO:0008626 is_a: CCO:P0000831 ! induction of apoptosis by extracellular signals [Term] id: CCO:P0000834 name: induction of apoptosis by ionic changes namespace: biological_process xref: GO:0008627 is_a: CCO:P0000831 ! induction of apoptosis by extracellular signals relationship: has_participant CCO:B0049439 ! RYR2_HUMAN [Term] id: CCO:P0000835 name: induction of apoptosis by hormones namespace: biological_process def: "Any process induced by hormones that directly activates any of the steps required for cell death by apoptosis." [GOC:bf] xref: GO:0008628 is_a: CCO:P0000831 ! induction of apoptosis by extracellular signals is_a: CCO:P0001994 ! induction of programmed cell death by hormones relationship: has_participant CCO:B0050794 ! SSR3_HUMAN relationship: has_participant CCO:B0054847 ! PTHY_HUMAN relationship: has_participant CCO:B0055607 ! SMS_HUMAN [Term] id: CCO:P0000836 name: induction of apoptosis by intracellular signals namespace: biological_process def: "Any process induced by intracellular signals that directly activates any of the steps required for cell death by apoptosis." [GOC:ai] xref: GO:0008629 xref: Reactome:109606 xref: Reactome:212064 xref: Reactome:221827 xref: Reactome:230395 xref: Reactome:238434 xref: Reactome:244996 xref: Reactome:249878 xref: Reactome:252597 xref: Reactome:255783 xref: Reactome:259177 xref: Reactome:262533 xref: Reactome:265360 xref: Reactome:268489 xref: Reactome:274214 xref: Reactome:280683 xref: Reactome:286703 xref: Reactome:288367 is_a: CCO:P0000672 ! induction of apoptosis relationship: has_participant CCO:B0001388 ! SNUT1_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001759 ! CUL1_HUMAN relationship: has_participant CCO:B0001760 ! CUL2_HUMAN relationship: has_participant CCO:B0001761 ! CUL3_HUMAN relationship: has_participant CCO:B0001762 ! CUL4A_HUMAN relationship: has_participant CCO:B0002027 ! CUL5_HUMAN relationship: has_participant CCO:B0002130 ! HIPK2_HUMAN relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: has_participant CCO:B0058197 ! LEG12_HUMAN [Term] id: CCO:P0000837 name: DNA damage response, signal transduction resulting in induction of apoptosis namespace: biological_process def: "A cascade of processes initiated by the detection of DNA damage and resulting in the induction of apoptosis (programmed cell death)." [GOC:go_curators] xref: GO:0008630 is_a: CCO:P0000836 ! induction of apoptosis by intracellular signals is_a: CCO:P0002125 ! DNA damage response, signal transduction relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0001461 ! ABL1_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0002121 ! Q9GZT1_HUMAN relationship: has_participant CCO:B0014938 ! AIFM1_HUMAN relationship: has_participant CCO:B0054566 ! CIDEA_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0057451 ! PGBD3_HUMAN relationship: has_participant CCO:B0059137 ! CIDEB_HUMAN [Term] id: CCO:P0000838 name: induction of apoptosis by oxidative stress namespace: biological_process def: "The activation, by oxidative stress, of any of the steps required for cell death by apoptosis." [GOC:ai] xref: GO:0008631 is_a: CCO:P0000836 ! induction of apoptosis by intracellular signals relationship: has_participant CCO:B0054465 ! PROD_HUMAN relationship: has_participant CCO:B0054910 ! GPX1_HUMAN relationship: has_participant CCO:B0056356 ! QORX_HUMAN relationship: has_participant CCO:B0059071 ! RBX2_HUMAN [Term] id: CCO:P0000839 name: apoptotic program namespace: biological_process def: "The intracellular signaling cascade that results when a cell is triggered to undergo apoptosis." [GOC:go_curators] xref: GO:0008632 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0005765 ! VDAC1_HUMAN relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0020068 ! PDIA2_HUMAN relationship: has_participant CCO:B0054566 ! CIDEA_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0055439 ! PSN2_HUMAN relationship: has_participant CCO:B0055530 ! CASP7_HUMAN relationship: has_participant CCO:B0055785 ! MCL1_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0058693 ! LITFL_HUMAN [Term] id: CCO:P0000840 name: activation of pro-apoptotic gene products namespace: biological_process def: "The conversion of proteins that induce or sustain apoptosis to an active form." [GOC:mah] synonym: "induction of pro-apoptotic gene products" RELATED [] xref: GO:0008633 xref: Reactome:111446 xref: Reactome:111447 xref: Reactome:111448 xref: Reactome:111452 xref: Reactome:114294 xref: Reactome:114452 xref: Reactome:139893 xref: Reactome:139895 xref: Reactome:139898 xref: Reactome:139910 xref: Reactome:139915 xref: Reactome:140534 xref: Reactome:206265 xref: Reactome:208870 xref: Reactome:211127 xref: Reactome:211606 xref: Reactome:211718 xref: Reactome:211799 xref: Reactome:211872 xref: Reactome:211873 xref: Reactome:211889 xref: Reactome:211890 xref: Reactome:211932 xref: Reactome:211933 xref: Reactome:211970 xref: Reactome:215841 xref: Reactome:218522 xref: Reactome:220975 xref: Reactome:221380 xref: Reactome:221488 xref: Reactome:221563 xref: Reactome:221637 xref: Reactome:221638 xref: Reactome:221653 xref: Reactome:221654 xref: Reactome:221697 xref: Reactome:221735 xref: Reactome:224996 xref: Reactome:227398 xref: Reactome:229645 xref: Reactome:230112 xref: Reactome:230169 xref: Reactome:230230 xref: Reactome:230244 xref: Reactome:230245 xref: Reactome:230407 xref: Reactome:238036 xref: Reactome:238269 xref: Reactome:238354 xref: Reactome:75108 is_a: CCO:P0002147 ! positive regulation of apoptosis relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005175 ! BAD_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005480 ! 1433B_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005638 ! MK08_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0006003 ! BIM_HUMAN relationship: has_participant CCO:B0006226 ! DYL1_HUMAN relationship: has_participant CCO:B0016299 ! PP2BC_HUMAN relationship: has_participant CCO:B0043605 ! DEDD2_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055624 ! CANB1_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: part_of CCO:P0000839 ! apoptotic program [Term] id: CCO:P0000841 name: negative regulation of survival gene product expression namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of survival gene product activity" EXACT [] synonym: "down-regulation of survival gene product activity" EXACT [] synonym: "downregulation of survival gene product activity" EXACT [] synonym: "inhibition of survival gene product activity" NARROW [] synonym: "negative regulation of survival gene product activity" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of survival gene products" EXACT [] xref: GO:0008634 is_a: CCO:P0001019 ! negative regulation of gene expression is_a: CCO:P0002591 ! regulation of survival gene product expression relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN relationship: has_participant CCO:B0054298 ! HRK_HUMAN [Term] id: CCO:P0000842 name: caspase activation via cytochrome c namespace: biological_process def: "Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, mediated by cytochrome c." [GOC:jl, http://en.wikipedia.org/wiki/ "Wikipedia"] xref: GO:0008635 xref: Reactome:111459 xref: Reactome:211727 xref: Reactome:221496 xref: Reactome:230117 xref: Reactome:238141 is_a: CCO:P0000673 ! caspase activation relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0054315 ! O00366_HUMAN relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0055677 ! CYC_HUMAN relationship: has_participant CCO:B0058311 ! AIFM3_HUMAN relationship: has_participant CCO:B0058884 ! DBLOH_HUMAN [Term] id: CCO:P0000843 name: caspase activation via phosphorylation namespace: biological_process def: "Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group." [GOC:jl, http://en.wikipedia.org/wiki/ "Wikipedia"] xref: GO:0008636 is_a: CCO:P0000673 ! caspase activation [Term] id: CCO:P0000844 name: apoptotic mitochondrial changes namespace: biological_process def: "The morphological and physiological alterations undergone by mitochondria during apoptosis." [GOC:mah] xref: GO:0008637 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0002185 ! PIM2_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN relationship: has_participant CCO:B0058494 ! AIFM2_HUMAN relationship: part_of CCO:P0000839 ! apoptotic program [Term] id: CCO:P0000845 name: dosage compensation, by hyperactivation of X chromosome namespace: biological_process def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome." [GOC:jl, ISBN:0140512888, PMID:11498577] synonym: "dosage compensation (sensu Insecta)" EXACT [] xref: GO:0009047 is_a: CCO:P0000803 ! dosage compensation [Term] id: CCO:P0000846 name: dosage compensation, by inactivation of X chromosome namespace: biological_process def: "Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex." [GOC:jl, ISBN:0140512888, PMID:11498577] synonym: "chromosome inactivation" BROAD [] synonym: "X chromosome inactivation" EXACT [] xref: GO:0009048 is_a: CCO:P0000803 ! dosage compensation [Term] id: CCO:P0000847 name: regulation of nucleoside metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of nucleoside metabolism" EXACT [] xref: GO:0009118 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0000848 name: positive regulation of transcription by pheromones namespace: biological_process def: "Any process involving pheromones that activates or increases the rate of transcription." [GOC:go_curators] subset: gosubset_prok synonym: "activation of transcription by pheromones" NARROW [] synonym: "stimulation of transcription by pheromones" NARROW [] synonym: "up regulation of transcription by pheromones" EXACT [] synonym: "up-regulation of transcription by pheromones" EXACT [] synonym: "upregulation of transcription by pheromones" EXACT [] xref: GO:0009371 is_a: CCO:P0000849 ! regulation of transcription by pheromones is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:P0000849 name: regulation of transcription by pheromones namespace: biological_process def: "Any process involving pheromones that modulates the frequency, rate or extent of transcription." [GOC:go_curators] subset: gosubset_prok xref: GO:0009373 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:P0000850 name: translational attenuation namespace: biological_process def: "Translational attentuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation." [PMID:15694341, PMID:15805513] subset: gosubset_prok xref: GO:0009386 is_a: CCO:P0000660 ! regulation of translation relationship: has_participant CCO:B0049899 ! YBOX2_HUMAN [Term] id: CCO:P0000851 name: phosphoenolpyruvate-dependent sugar phosphotransferase system namespace: biological_process def: "The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC." [http://www.ucs.mun.ca/~n55lrb/general_pts.html] subset: gosubset_prok synonym: "PTS system" NARROW [] xref: GO:0009401 is_a: CCO:P0000708 ! signal transduction [Term] id: CCO:P0000852 name: induction of phytoalexin biosynthetic process namespace: biological_process def: "The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection." [ISBN:0943088399] synonym: "induction of phytoalexin anabolism" EXACT [] synonym: "induction of phytoalexin biosynthesis" EXACT [] synonym: "induction of phytoalexin formation" EXACT [] synonym: "induction of phytoalexin synthesis" EXACT [] xref: GO:0009689 is_a: CCO:P0003202 ! positive regulation of phytoalexin biosynthetic process [Term] id: CCO:P0000853 name: auxin mediated signaling pathway namespace: biological_process def: "The series of molecular signals generated in response to detection of auxin." [GOC:mah, GOC:sm] synonym: "auxin mediated signalling" EXACT [] xref: GO:0009734 is_a: CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:P0000854 name: cytokinin mediated signaling namespace: biological_process def: "A series of molecular signals induced by the detection of cytokinin." [GOC:sm] synonym: "cytokinin mediated signalling" EXACT [] xref: GO:0009736 is_a: CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:P0000855 name: abscisic acid mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of abscisic acid." [GOC:sm] synonym: "abscisic acid mediated signalling" EXACT [] xref: GO:0009738 is_a: CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:P0000856 name: gibberellic acid mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of gibberellic acid." [GOC:sm] synonym: "GA-signaling" EXACT [] synonym: "gibberellic acid mediated signalling" EXACT [] synonym: "gibberellic acid signaling" EXACT [] xref: GO:0009740 is_a: CCO:P0000948 ! gibberellin-mediated signaling [Term] id: CCO:P0000857 name: brassinosteroid mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of brassinosteroid." [GOC:sm] synonym: "brassinosteroid mediated signalling" EXACT [] xref: GO:0009742 is_a: CCO:P0002207 ! steroid hormone mediated signaling [Term] id: CCO:P0000858 name: sucrose mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of sucrose." [GOC:sm] synonym: "sucrose mediated signalling" EXACT [] xref: GO:0009745 is_a: CCO:P0000915 ! sugar mediated signaling [Term] id: CCO:P0000859 name: hexokinase-dependent signaling namespace: biological_process def: "A series of molecular signals mediated by hexose and dependent on the detection of hexokinase." [GOC:mah, GOC:sm] synonym: "hexokinase-dependent signalling" EXACT [] xref: GO:0009747 is_a: CCO:P0000863 ! hexose mediated signaling [Term] id: CCO:P0000860 name: hexokinase-independent signaling namespace: biological_process def: "A series of molecular signals mediated by hexose and independent of hexokinase." [GOC:mah, GOC:sm] synonym: "hexokinase-independent signalling" EXACT [] xref: GO:0009748 is_a: CCO:P0000863 ! hexose mediated signaling [Term] id: CCO:P0000861 name: hormone-mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of a hormone." [GOC:sm] synonym: "hormone mediated signalling" EXACT [] xref: GO:0009755 xref: Reactome:163359 xref: Reactome:212022 xref: Reactome:221785 xref: Reactome:230363 xref: Reactome:238400 xref: Reactome:244950 xref: Reactome:249830 xref: Reactome:252563 xref: Reactome:255742 xref: Reactome:259135 xref: Reactome:262492 xref: Reactome:268452 xref: Reactome:286664 xref: Reactome:288341 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0005298 ! KAP0_HUMAN relationship: has_participant CCO:B0015122 ! GLR_HUMAN relationship: has_participant CCO:B0018532 ! KAPCG_HUMAN relationship: has_participant CCO:B0018534 ! KAPCB_HUMAN relationship: has_participant CCO:B0018543 ! KAPCA_HUMAN relationship: has_participant CCO:B0021337 ! KAP1_HUMAN relationship: has_participant CCO:B0021450 ! ADR2_HUMAN relationship: has_participant CCO:B0021461 ! ADR1_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0022454 ! KAP3_HUMAN relationship: has_participant CCO:B0022455 ! KAP2_HUMAN relationship: has_participant CCO:B0027550 ! GNAS2_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0054303 ! AGRP_HUMAN relationship: has_participant CCO:B0054537 ! GBG7_HUMAN relationship: has_participant CCO:B0054848 ! GLUC_HUMAN relationship: has_participant CCO:B0055056 ! GBB3_HUMAN relationship: has_participant CCO:B0055122 ! TRH_HUMAN relationship: has_participant CCO:B0055325 ! ADCY8_HUMAN relationship: has_participant CCO:B0055347 ! ASIP_HUMAN relationship: has_participant CCO:B0055443 ! GBG4_HUMAN relationship: has_participant CCO:B0055444 ! GBG10_HUMAN relationship: has_participant CCO:B0055589 ! GBG2_HUMAN relationship: has_participant CCO:B0055614 ! GBG11_HUMAN relationship: has_participant CCO:B0055621 ! GBB1_HUMAN relationship: has_participant CCO:B0055623 ! GBB2_HUMAN relationship: has_participant CCO:B0055632 ! GBG3_HUMAN relationship: has_participant CCO:B0055633 ! GBG5_HUMAN relationship: has_participant CCO:B0055794 ! ADCY1_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN relationship: has_participant CCO:B0058769 ! GBB4_HUMAN relationship: has_participant CCO:B0059061 ! GBG13_HUMAN relationship: has_participant CCO:B0059075 ! GBG12_HUMAN relationship: has_participant CCO:B0059182 ! GBG8_HUMAN relationship: has_participant CCO:B0059357 ! JHD2A_HUMAN [Term] id: CCO:P0000862 name: carbohydrate mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of carbohydrate." [GOC:sm] synonym: "carbohydrate mediated signalling" EXACT [] xref: GO:0009756 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0056521 ! COL12_HUMAN relationship: has_participant CCO:B0058327 ! Q96PA4_HUMAN relationship: has_participant CCO:B0058561 ! CLC7A_HUMAN [Term] id: CCO:P0000863 name: hexose mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of hexose." [GOC:sm] synonym: "hexose mediated signalling" EXACT [] xref: GO:0009757 is_a: CCO:P0000862 ! carbohydrate mediated signaling [Term] id: CCO:P0000864 name: blue light signaling pathway namespace: biological_process def: "The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 440nm and 500nm." [GOC:lr, GOC:sm] synonym: "blue light signalling pathway" EXACT [] xref: GO:0009785 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0000865 name: regulation of asymmetric cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of asymmetric cell division." [GOC:lr] xref: GO:0009786 is_a: CCO:P0003078 ! regulation of cell division relationship: regulates CCO:P0000821 ! asymmetric cell division [Term] id: CCO:P0000866 name: regulation of abscisic acid mediated signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by abscisic acid." [GOC:lr] synonym: "regulation of abscisic acid mediated signalling" EXACT [] xref: GO:0009787 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0000855 ! abscisic acid mediated signaling [Term] id: CCO:P0000867 name: negative regulation of abscisic acid mediated signaling namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by abscisic acid." [GOC:lr] synonym: "down regulation of abscisic acid mediated signaling" EXACT [] synonym: "down-regulation of abscisic acid mediated signaling" EXACT [] synonym: "downregulation of abscisic acid mediated signaling" EXACT [] synonym: "inhibition of abscisic acid mediated signaling" NARROW [] synonym: "negative regulation of abscisic acid mediated signalling" EXACT [] xref: GO:0009788 is_a: CCO:P0000866 ! regulation of abscisic acid mediated signaling is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: negatively_regulates CCO:P0000855 ! abscisic acid mediated signaling [Term] id: CCO:P0000868 name: positive regulation of abscisic acid mediated signaling namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of abscisic acid mediated signal transduction." [GOC:lr] synonym: "activation of abscisic acid mediated signaling" NARROW [] synonym: "positive regulation of abscisic acid mediated signalling" EXACT [] synonym: "stimulation of abscisic acid mediated signaling" NARROW [] synonym: "up regulation of abscisic acid mediated signaling" EXACT [] synonym: "up-regulation of abscisic acid mediated signaling" EXACT [] synonym: "upregulation of abscisic acid mediated signaling" EXACT [] xref: GO:0009789 is_a: CCO:P0000866 ! regulation of abscisic acid mediated signaling is_a: CCO:P0000885 ! positive regulation of signal transduction relationship: positively_regulates CCO:P0000855 ! abscisic acid mediated signaling [Term] id: CCO:P0000869 name: systemic acquired resistance, salicylic acid mediated signaling pathway namespace: biological_process def: "The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance." [GOC:jy] synonym: "salicylic acid mediated signaling pathway (systemic acquired resistance)" EXACT [] synonym: "systemic acquired resistance, salicylic acid mediated signalling pathway" EXACT [] xref: GO:0009862 is_a: CCO:P0000870 ! salicylic acid mediated signaling pathway [Term] id: CCO:P0000870 name: salicylic acid mediated signaling pathway namespace: biological_process def: "A series of molecular signals mediated by salicylic acid." [GOC:jy] synonym: "salicylic acid mediated signalling pathway" EXACT [] xref: GO:0009863 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0000871 name: induced systemic resistance, jasmonic acid mediated signaling pathway namespace: biological_process def: "The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance." [GOC:jy] synonym: "induced systemic resistance, jasmonic acid mediated signalling pathway" EXACT [] synonym: "jasmonic acid mediated signaling pathway (induced systemic resistance)" EXACT [] xref: GO:0009864 is_a: CCO:P0000873 ! jasmonic acid mediated signaling pathway [Term] id: CCO:P0000872 name: induced systemic resistance, ethylene mediated signaling pathway namespace: biological_process def: "The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance." [GOC:jy] synonym: "ethene mediated signaling pathway (induced systemic resistance)" EXACT [] synonym: "ethylene mediated signaling pathway (induced systemic resistance)" EXACT [] synonym: "induced systemic resistance, ethene mediated signaling pathway" EXACT [] synonym: "induced systemic resistance, ethene mediated signalling pathway" EXACT [] synonym: "induced systemic resistance, ethylene mediated signalling pathway" EXACT [] xref: GO:0009866 is_a: CCO:P0000877 ! ethylene mediated signaling pathway [Term] id: CCO:P0000873 name: jasmonic acid mediated signaling pathway namespace: biological_process def: "A series of molecular signals mediated by jasmonic acid." [GOC:jy] synonym: "jasmonic acid mediated signalling pathway" EXACT [] xref: GO:0009867 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0000874 name: jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway namespace: biological_process def: "The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance." [GOC:jy] synonym: "jasmonic acid and ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway" EXACT [] synonym: "jasmonic acid mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)" EXACT [] synonym: "jasmonic acid mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)" EXACT [] synonym: "jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway" EXACT [] synonym: "jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signalling pathway" EXACT [] synonym: "jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway" EXACT [] synonym: "jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signalling pathway" EXACT [] xref: GO:0009868 is_a: CCO:P0000873 ! jasmonic acid mediated signaling pathway [Term] id: CCO:P0000875 name: defense response signaling pathway, resistance gene-dependent namespace: biological_process def: "A series of molecular signals that depends upon R-genes and is activated during defense response." [GOC:jy, GOC:mah, PMID:11418339] synonym: "defence response signaling pathway, resistance gene-dependent" EXACT [] synonym: "defence response signalling pathway, resistance gene-dependent" EXACT [] synonym: "defense response signalling pathway, resistance gene-dependent" EXACT [] xref: GO:0009870 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0000876 name: jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway namespace: biological_process def: "The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance." [GOC:jy] synonym: "ethene mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)" EXACT [] synonym: "ethylene mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)" EXACT [] synonym: "jasmonic acid and ethene-dependent systemic resistance, ethene mediated signaling pathway" EXACT [] synonym: "jasmonic acid/ethene-dependent systemic resistance, ethene mediated signaling pathway" EXACT [] synonym: "jasmonic acid/ethene-dependent systemic resistance, ethene mediated signalling pathway" EXACT [] synonym: "jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signaling pathway" EXACT [] synonym: "jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signalling pathway" EXACT [] xref: GO:0009871 is_a: CCO:P0000877 ! ethylene mediated signaling pathway [Term] id: CCO:P0000877 name: ethylene mediated signaling pathway namespace: biological_process def: "A series of molecular signals mediated by ethylene (ethene)." [GOC:jy] synonym: "ethene mediated signaling pathway" EXACT [] synonym: "ethene mediated signalling pathway" EXACT [] synonym: "ethylene mediated signalling pathway" EXACT [] xref: GO:0009873 is_a: CCO:P0000401 ! two-component signal transduction system (phosphorelay) is_a: CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:P0000878 name: regulation of gibberellic acid mediated signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling." [GOC:go_curators] synonym: "regulation of gibberellic acid mediated signalling" EXACT [] xref: GO:0009937 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0000856 ! gibberellic acid mediated signaling [Term] id: CCO:P0000879 name: negative regulation of gibberellic acid mediated signaling namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity." [GOC:sm] synonym: "down regulation of gibberellic acid mediated signaling" EXACT [] synonym: "down-regulation of gibberellic acid mediated signaling" EXACT [] synonym: "downregulation of gibberellic acid mediated signaling" EXACT [] synonym: "inhibition of gibberellic acid mediated signaling" NARROW [] synonym: "negative regulation of gibberellic acid mediated signalling" EXACT [] xref: GO:0009938 is_a: CCO:P0000878 ! regulation of gibberellic acid mediated signaling is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: negatively_regulates CCO:P0000856 ! gibberellic acid mediated signaling [Term] id: CCO:P0000880 name: positive regulation of gibberellic acid mediated signaling namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity." [GOC:sm] synonym: "activation of gibberellic acid mediated signaling" NARROW [] synonym: "positive regulation of gibberellic acid mediated signalling" EXACT [] synonym: "stimulation of gibberellic acid mediated signaling" NARROW [] synonym: "up regulation of gibberellic acid mediated signaling" EXACT [] synonym: "up-regulation of gibberellic acid mediated signaling" EXACT [] synonym: "upregulation of gibberellic acid mediated signaling" EXACT [] xref: GO:0009939 is_a: CCO:P0000878 ! regulation of gibberellic acid mediated signaling is_a: CCO:P0000885 ! positive regulation of signal transduction relationship: positively_regulates CCO:P0000856 ! gibberellic acid mediated signaling [Term] id: CCO:P0000881 name: regulation of flavonoid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids." [GOC:tb] subset: gosubset_prok synonym: "regulation of flavonoid anabolism" EXACT [] synonym: "regulation of flavonoid biosynthesis" EXACT [] synonym: "regulation of flavonoid formation" EXACT [] synonym: "regulation of flavonoid synthesis" EXACT [] xref: GO:0009962 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000882 name: positive regulation of flavonoid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids." [GOC:tb] subset: gosubset_prok synonym: "activation of flavonoid biosynthetic process" NARROW [] synonym: "positive regulation of flavonoid anabolism" EXACT [] synonym: "positive regulation of flavonoid biosynthesis" EXACT [] synonym: "positive regulation of flavonoid formation" EXACT [] synonym: "positive regulation of flavonoid synthesis" EXACT [] synonym: "stimulation of flavonoid biosynthetic process" NARROW [] synonym: "up regulation of flavonoid biosynthetic process" EXACT [] synonym: "up-regulation of flavonoid biosynthetic process" EXACT [] synonym: "upregulation of flavonoid biosynthetic process" EXACT [] xref: GO:0009963 is_a: CCO:P0000881 ! regulation of flavonoid biosynthetic process is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process [Term] id: CCO:P0000883 name: negative regulation of flavonoid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids." [GOC:tb] subset: gosubset_prok synonym: "down regulation of flavonoid biosynthetic process" EXACT [] synonym: "down-regulation of flavonoid biosynthetic process" EXACT [] synonym: "downregulation of flavonoid biosynthetic process" EXACT [] synonym: "inhibition of flavonoid biosynthetic process" NARROW [] synonym: "negative regulation of flavonoid anabolism" EXACT [] synonym: "negative regulation of flavonoid biosynthesis" EXACT [] synonym: "negative regulation of flavonoid formation" EXACT [] synonym: "negative regulation of flavonoid synthesis" EXACT [] xref: GO:0009964 is_a: CCO:P0000881 ! regulation of flavonoid biosynthetic process is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process [Term] id: CCO:P0000884 name: regulation of signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm] subset: gosubset_prok xref: GO:0009966 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0002128 ! TSYL2_HUMAN relationship: has_participant CCO:B0005489 ! 1433G_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0053765 ! A4FVB3_HUMAN relationship: has_participant CCO:B0054082 ! A8MWS2_HUMAN relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0054396 ! IPP4_HUMAN relationship: has_participant CCO:B0054499 ! SPY1_HUMAN relationship: has_participant CCO:B0054500 ! SPY3_HUMAN relationship: has_participant CCO:B0055339 ! IPP2_HUMAN relationship: has_participant CCO:B0055637 ! IGBP1_HUMAN relationship: has_participant CCO:B0056215 ! SPRE3_HUMAN relationship: has_participant CCO:B0056454 ! Q5JPN0_HUMAN relationship: has_participant CCO:B0056579 ! Q5T4Y8_HUMAN relationship: has_participant CCO:B0056868 ! IPP2M_HUMAN relationship: has_participant CCO:B0056869 ! Q6NXS2_HUMAN relationship: has_participant CCO:B0056898 ! CNKR3_HUMAN relationship: has_participant CCO:B0057074 ! Q6ZU68_HUMAN relationship: has_participant CCO:B0057077 ! Q6ZUP3_HUMAN relationship: has_participant CCO:B0057194 ! SPRE2_HUMAN relationship: has_participant CCO:B0057195 ! SPRE1_HUMAN relationship: has_participant CCO:B0057208 ! Q7Z783_HUMAN relationship: has_participant CCO:B0058022 ! CNKR2_HUMAN relationship: has_participant CCO:B0058341 ! IPP2L_HUMAN relationship: has_participant CCO:B0058614 ! SPY4_HUMAN relationship: has_participant CCO:B0058903 ! C42S2_HUMAN relationship: has_participant CCO:B0058907 ! GLRX2_HUMAN relationship: has_participant CCO:B0059001 ! MTCH1_HUMAN relationship: regulates CCO:P0000708 ! signal transduction [Term] id: CCO:P0000885 name: positive regulation of signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm] subset: gosubset_prok synonym: "activation of signal transduction" NARROW [] synonym: "stimulation of signal transduction" NARROW [] synonym: "up regulation of signal transduction" EXACT [] synonym: "up-regulation of signal transduction" EXACT [] synonym: "upregulation of signal transduction" EXACT [] xref: GO:0009967 xref: Reactome:110518 is_a: CCO:P0000884 ! regulation of signal transduction is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0055268 ! CD80_HUMAN relationship: positively_regulates CCO:P0000708 ! signal transduction [Term] id: CCO:P0000886 name: negative regulation of signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction." [GOC:sm] subset: gosubset_prok synonym: "down regulation of signal transduction" EXACT [] synonym: "down-regulation of signal transduction" EXACT [] synonym: "downregulation of signal transduction" EXACT [] synonym: "inhibition of signal transduction" NARROW [] xref: GO:0009968 xref: Reactome:110485 is_a: CCO:P0000884 ! regulation of signal transduction is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0001605 ! RGS2_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0005471 ! BRAP_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN relationship: has_participant CCO:B0020764 ! RGS20_HUMAN relationship: has_participant CCO:B0020765 ! RGS21_HUMAN relationship: has_participant CCO:B0020766 ! RGS5_HUMAN relationship: has_participant CCO:B0020768 ! RGS16_HUMAN relationship: has_participant CCO:B0020771 ! RGS3_HUMAN relationship: has_participant CCO:B0020776 ! RGS19_HUMAN relationship: has_participant CCO:B0020777 ! RGS13_HUMAN relationship: has_participant CCO:B0020780 ! RGS1_HUMAN relationship: has_participant CCO:B0020787 ! RGS18_HUMAN relationship: has_participant CCO:B0020790 ! RGS8_HUMAN relationship: has_participant CCO:B0026710 ! RGS4_HUMAN relationship: has_participant CCO:B0026717 ! RGS17_HUMAN relationship: has_participant CCO:B0033323 ! RGS12_HUMAN relationship: has_participant CCO:B0033332 ! RGS14_HUMAN relationship: has_participant CCO:B0033333 ! RGS10_HUMAN relationship: has_participant CCO:B0054345 ! SOCS2_HUMAN relationship: has_participant CCO:B0054347 ! SOCS7_HUMAN relationship: has_participant CCO:B0054349 ! SOCS6_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN relationship: has_participant CCO:B0054678 ! RGS9_HUMAN relationship: has_participant CCO:B0054700 ! RGS11_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN relationship: has_participant CCO:B0055433 ! RGS6_HUMAN relationship: has_participant CCO:B0055438 ! RGS7_HUMAN relationship: has_participant CCO:B0055574 ! NAL12_HUMAN relationship: has_participant CCO:B0056004 ! IHH_HUMAN relationship: has_participant CCO:B0056842 ! R7BP_HUMAN relationship: has_participant CCO:B0057050 ! R9BP_HUMAN relationship: has_participant CCO:B0057587 ! RGS22_HUMAN relationship: has_participant CCO:B0058020 ! SOCS4_HUMAN relationship: has_participant CCO:B0058188 ! DDT4L_HUMAN relationship: has_participant CCO:B0058919 ! CISH_HUMAN relationship: has_participant CCO:B0058940 ! PK1IP_HUMAN relationship: has_participant CCO:B0058946 ! DDT4_HUMAN relationship: has_participant CCO:B0059390 ! SNX13_HUMAN relationship: negatively_regulates CCO:P0000708 ! signal transduction [Term] id: CCO:P0000887 name: cellular process namespace: biological_process def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] subset: goslim_goa subset: goslim_pir subset: goslim_plant subset: gosubset_prok synonym: "cell growth and/or maintenance" NARROW [] synonym: "cell physiology" EXACT [] synonym: "cellular physiological process" EXACT [] xref: GO:0008151 xref: GO:0009987 xref: GO:0050875 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001487 ! JUN_HUMAN relationship: has_participant CCO:B0001530 ! JUNB_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN relationship: has_participant CCO:B0023169 ! A6NMR0_HUMAN relationship: has_participant CCO:B0023175 ! AMD_HUMAN relationship: has_participant CCO:B0053850 ! MOXD2_HUMAN relationship: has_participant CCO:B0054941 ! DOPO_HUMAN relationship: has_participant CCO:B0055504 ! NDST2_HUMAN relationship: has_participant CCO:B0056567 ! Q5T382_HUMAN relationship: has_participant CCO:B0056951 ! MOXD1_HUMAN [Term] id: CCO:P0000888 name: negative regulation of cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from adopting a specific cell fate." [GOC:go_curators] synonym: "down regulation of cell fate specification" EXACT [] synonym: "down-regulation of cell fate specification" EXACT [] synonym: "downregulation of cell fate specification" EXACT [] synonym: "inhibition of cell fate specification" NARROW [] synonym: "suppression of cell fate" EXACT [] xref: GO:0009996 is_a: CCO:P0000941 ! negative regulation of cell fate commitment is_a: CCO:P0002105 ! regulation of cell fate specification relationship: has_participant CCO:B0002083 ! GFI1_HUMAN [Term] id: CCO:P0000889 name: negative regulation of cardioblast cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from specifying into a cardioblast." [GOC:go_curators] synonym: "down regulation of cardioblast cell fate specification" EXACT [] synonym: "down-regulation of cardioblast cell fate specification" EXACT [] synonym: "downregulation of cardioblast cell fate specification" EXACT [] synonym: "inhibition of cardioblast cell fate specification" NARROW [] synonym: "suppression of cardioblast cell fate" EXACT [] xref: GO:0009997 xref: GO:0042687 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0002117 ! regulation of cardioblast cell fate specification [Term] id: CCO:P0000890 name: negative regulation of retinal cone cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell." [GOC:go_curators] synonym: "down regulation of retinal cone cell fate specification" EXACT [] synonym: "down-regulation of retinal cone cell fate specification" EXACT [] synonym: "downregulation of retinal cone cell fate specification" EXACT [] synonym: "inhibition of retinal cone cell fate specification" NARROW [] synonym: "negative regulation of retina cone cell fate specification" EXACT [] synonym: "suppression of retina cone cell fate" EXACT [] synonym: "suppression of retinal cone cell fate" EXACT [] xref: GO:0009998 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0002114 ! regulation of retinal cone cell fate specification [Term] id: CCO:P0000891 name: negative regulation of auditory receptor cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell." [GOC:go_curators] synonym: "down regulation of auditory receptor cell fate specification" EXACT [] synonym: "down-regulation of auditory receptor cell fate specification" EXACT [] synonym: "downregulation of auditory receptor cell fate specification" EXACT [] synonym: "inhibition of auditory receptor cell fate specification" NARROW [] synonym: "negative regulation of auditory hair cell fate specification" EXACT [] synonym: "suppression of auditory receptor cell fate" EXACT [] synonym: "suppression of hair cell fate" EXACT [] xref: GO:0009999 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0002113 ! regulation of auditory receptor cell fate specification [Term] id: CCO:P0000892 name: red or far red light signaling pathway namespace: biological_process def: "The series of molecular signals initiated upon sensing by photoreceptor molecules of red light at 660nm or far red light at 730nm." [GOC:lr, GOC:sm] synonym: "phytochrome signaling pathway" BROAD [] synonym: "red or far red light signalling pathway" EXACT [] synonym: "red/far red light signaling pathway" EXACT [] xref: GO:0010017 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0000893 name: far red light signaling pathway namespace: biological_process def: "The series of molecular signals initiated upon sensing of far red light by photoreceptor molecule at 730 nm." [GOC:lr, GOC:sm] synonym: "far red light signalling pathway" EXACT [] xref: GO:0010018 is_a: CCO:P0000892 ! red or far red light signaling pathway [Term] id: CCO:P0000894 name: chloroplast-nucleus signaling pathway namespace: biological_process def: "The process by which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis." [PMID:8972595] synonym: "chloroplast-nucleus signalling pathway" EXACT [] xref: GO:0010019 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0000895 name: regulation of atrichoblast fate specification namespace: biological_process def: "Any process that modulates atrichoblast fate specification." [GOC:tb] xref: GO:0010058 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0000896 name: positive regulation of atrichoblast fate specification namespace: biological_process def: "Any process that induces or promotes atrichoblast fate specification." [GOC:tb] synonym: "activation of atrichoblast fate" NARROW [] synonym: "stimulation of atrichoblast fate" NARROW [] synonym: "up regulation of atrichoblast fate" EXACT [] synonym: "up-regulation of atrichoblast fate" EXACT [] synonym: "upregulation of atrichoblast fate" EXACT [] xref: GO:0010059 is_a: CCO:P0000895 ! regulation of atrichoblast fate specification is_a: CCO:P0002106 ! positive regulation of cell fate specification [Term] id: CCO:P0000897 name: negative regulation of atrichoblast fate specification namespace: biological_process def: "Any process that suppresses atrichoblast fate specification." [GOC:tb] synonym: "down regulation of atrichoblast fate" EXACT [] synonym: "down-regulation of atrichoblast fate" EXACT [] synonym: "downregulation of atrichoblast fate" EXACT [] synonym: "inhibition of atrichoblast fate" NARROW [] xref: GO:0010060 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0000895 ! regulation of atrichoblast fate specification [Term] id: CCO:P0000898 name: regulation of trichoblast fate specification namespace: biological_process def: "Any process that modulates trichoblast fate specification." [GOC:tb] xref: GO:0010061 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0000899 name: negative regulation of trichoblast fate specification namespace: biological_process def: "Any process that suppresses trichoblast fate specification." [GOC:tb] synonym: "down regulation of trichoblast fate" EXACT [] synonym: "down-regulation of trichoblast fate" EXACT [] synonym: "downregulation of trichoblast fate" EXACT [] synonym: "inhibition of trichoblast fate" NARROW [] xref: GO:0010062 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0000898 ! regulation of trichoblast fate specification [Term] id: CCO:P0000900 name: positive regulation of trichoblast fate specification namespace: biological_process def: "Any process that induces or promotes trichoblast fate specification." [GOC:tb] synonym: "activation of trichoblast fate" NARROW [] synonym: "stimulation of trichoblast fate" NARROW [] synonym: "up regulation of trichoblast fate" EXACT [] synonym: "up-regulation of trichoblast fate" EXACT [] synonym: "upregulation of trichoblast fate" EXACT [] xref: GO:0010063 is_a: CCO:P0000898 ! regulation of trichoblast fate specification is_a: CCO:P0002106 ! positive regulation of cell fate specification [Term] id: CCO:P0000901 name: zygote asymmetric cell division namespace: biological_process def: "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." [GOC:tb] synonym: "zygote asymmetric cytokinesis" RELATED [] xref: GO:0010070 is_a: CCO:P0000821 ! asymmetric cell division [Term] id: CCO:P0000902 name: maintenance of meristem identity namespace: biological_process def: "The process by which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:tb] synonym: "maintenance of meristem cell identity" EXACT [] synonym: "meristem cell maintenance" EXACT [] xref: GO:0010074 xref: GO:0032503 is_a: CCO:P0001147 ! stem cell maintenance [Term] id: CCO:P0000903 name: maintenance of floral meristem identity namespace: biological_process def: "Any process involved in maintaining the identity of a floral meristem. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] xref: GO:0010076 is_a: CCO:P0000902 ! maintenance of meristem identity [Term] id: CCO:P0000904 name: maintenance of inflorescence meristem identity namespace: biological_process def: "Any process involved in maintaining the identity of an inflorescence meristem. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] xref: GO:0010077 is_a: CCO:P0000902 ! maintenance of meristem identity [Term] id: CCO:P0000905 name: maintenance of root meristem identity namespace: biological_process def: "Any process involved in maintaining the identity of a root meristem. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] xref: GO:0010078 is_a: CCO:P0000902 ! maintenance of meristem identity [Term] id: CCO:P0000906 name: maintenance of vegetative meristem identity namespace: biological_process def: "Any process involved in maintaining the identity of a vegetative meristem. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tb] xref: GO:0010079 is_a: CCO:P0000902 ! maintenance of meristem identity [Term] id: CCO:P0000907 name: regulation of ethylene mediated signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ethylene (ethene) mediated signaling." [GOC:tb] synonym: "regulation of ethene mediated signaling pathway" EXACT [] synonym: "regulation of ethene mediated signalling pathway" EXACT [] synonym: "regulation of ethylene mediated signalling pathway" EXACT [] xref: GO:0010104 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0000877 ! ethylene mediated signaling pathway [Term] id: CCO:P0000908 name: negative regulation of ethylene mediated signaling pathway namespace: biological_process def: "Any process that stops or prevents ethylene (ethene) mediated signaling." [GOC:tb] synonym: "down regulation of ethylene mediated signaling pathway" EXACT [] synonym: "down-regulation of ethylene mediated signaling pathway" EXACT [] synonym: "downregulation of ethylene mediated signaling pathway" EXACT [] synonym: "inhibition of ethylene mediated signaling pathway" NARROW [] synonym: "negative regulation of ethene mediated signaling pathway" EXACT [] synonym: "negative regulation of ethene mediated signalling pathway" EXACT [] synonym: "negative regulation of ethylene mediated signalling pathway" EXACT [] xref: GO:0010105 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0000907 ! regulation of ethylene mediated signaling pathway relationship: negatively_regulates CCO:P0000877 ! ethylene mediated signaling pathway [Term] id: CCO:P0000909 name: regulation of photosynthesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of photosynthesis." [GOC:sm] subset: gosubset_prok xref: GO:0010109 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0000910 name: regulation of photosynthesis, dark reaction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of photosynthesis dark reaction." [GOC:sm] xref: GO:0010110 is_a: CCO:P0000909 ! regulation of photosynthesis [Term] id: CCO:P0000911 name: regulation of abscisic acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid." [GOC:sm] subset: gosubset_prok synonym: "regulation of abscisic acid anabolism" EXACT [] synonym: "regulation of abscisic acid biosynthesis" EXACT [] synonym: "regulation of abscisic acid formation" EXACT [] synonym: "regulation of abscisic acid synthesis" EXACT [] xref: GO:0010115 is_a: CCO:P0001146 ! regulation of isoprenoid metabolic process is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000912 name: positive regulation of abscisic acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid." [GOC:sm] subset: gosubset_prok synonym: "activation of abscisic acid biosynthetic process" NARROW [] synonym: "positive regulation of abscisic acid anabolism" EXACT [] synonym: "positive regulation of abscisic acid biosynthesis" EXACT [] synonym: "positive regulation of abscisic acid formation" EXACT [] synonym: "positive regulation of abscisic acid synthesis" EXACT [] synonym: "stimulation of abscisic acid biosynthetic process" NARROW [] synonym: "up regulation of abscisic acid biosynthetic process" EXACT [] synonym: "up-regulation of abscisic acid biosynthetic process" EXACT [] synonym: "upregulation of abscisic acid biosynthetic process" EXACT [] xref: GO:0010116 is_a: CCO:P0000911 ! regulation of abscisic acid biosynthetic process is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0002571 ! positive regulation of isoprenoid metabolic process [Term] id: CCO:P0000913 name: regulation of stomatal movement namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stomatal movement." [GOC:sm] xref: GO:0010119 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0000914 name: red light signaling pathway namespace: biological_process def: "The series of molecular signals initiated upon sensing of red light by photoreceptor molecule at 660 nm." [GOC:sm] synonym: "red light signalling pathway" EXACT [] xref: GO:0010161 is_a: CCO:P0000892 ! red or far red light signaling pathway [Term] id: CCO:P0000915 name: sugar mediated signaling namespace: biological_process def: "The process by which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes." [PMID:9014361] synonym: "sugar mediated signalling" EXACT [] xref: GO:0010182 is_a: CCO:P0000862 ! carbohydrate mediated signaling [Term] id: CCO:P0000916 name: defense response signaling pathway, resistance gene-independent namespace: biological_process def: "A series of molecular signals that is activated during defense response and does not depend upon R-genes." [GOC:mah, GOC:sm] synonym: "defence response signaling pathway, resistance gene-independent" EXACT [] synonym: "defence response signalling pathway, resistance gene-independent" EXACT [] xref: GO:0010204 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0000917 name: photoinhibition namespace: biological_process def: "The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II." [GOC:mtg_electron_transport, PMID:12068126] synonym: "photosystem II inhibition" BROAD [] xref: GO:0010205 is_a: CCO:P0002169 ! negative regulation of photosynthesis, light reaction [Term] id: CCO:P0000918 name: maintenance of DNA methylation namespace: biological_process def: "Any process involved in maintaining the methylation state of a nucleotide sequence." [PMID:11898023] xref: GO:0010216 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0002161 ! HELLS_HUMAN relationship: part_of CCO:P0000646 ! DNA methylation [Term] id: CCO:P0000919 name: glucose mediated signaling namespace: biological_process def: "The process by which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes." [GOC:sm] synonym: "glucose mediated signalling" EXACT [] xref: GO:0010255 is_a: CCO:P0000863 ! hexose mediated signaling [Term] id: CCO:P0000920 name: RNA interference, production of ta-siRNAs namespace: biological_process def: "Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs." [GOC:tb, PMID:16129836] xref: GO:0010267 is_a: CCO:P0001260 ! RNA interference, production of siRNA [Term] id: CCO:P0000921 name: regulation of chlorophyll catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll." [PMID:16361392] xref: GO:0010271 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0003056 ! regulation of cofactor metabolic process [Term] id: CCO:P0000922 name: regulation of hydrogen peroxide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions involving hydrogen peroxide." [PMID:14765119] synonym: "regulation of hydrogen peroxide metabolism" EXACT [] xref: GO:0010310 is_a: CCO:P0001404 ! regulation of cellular metabolic process relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0025802 ! RAC2_HUMAN relationship: has_participant CCO:B0057254 ! NOXA1_HUMAN relationship: has_participant CCO:B0057598 ! NOXO1_HUMAN [Term] id: CCO:P0000923 name: regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)." [PMID:16531478] xref: GO:0010322 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000924 name: negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent)." [PMID:16531478] synonym: "down regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] synonym: "down-regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] synonym: "downregulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" EXACT [] synonym: "inhibition of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway" NARROW [] xref: GO:0010323 is_a: CCO:P0000923 ! regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process [Term] id: CCO:P0000925 name: regulation of salicylic acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions involving salicylic acid." [PMID:14765119] synonym: "regulation of salicylic acid metabolism" RELATED [] xref: GO:0010337 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0000926 name: regulation of plant-type hypersensitive response namespace: biological_process def: "Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response." [PMID:16255244] comment: Note that term is to be used to annotate gene products in the plant. To annotate genes in a symbiont, consider the biological process term 'modulation by symbiont of host programmed cell death ; GO:0052040'. synonym: "regulation of HR" EXACT [] synonym: "regulation of HR-PCD" EXACT [] synonym: "regulation of plant hypersensitive response" EXACT [] xref: GO:0010363 is_a: CCO:P0002149 ! regulation of programmed cell death [Term] id: CCO:P0000927 name: regulation of ethylene biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of ethylene biosynthetic process." [GOC:tair_curators] xref: GO:0010364 is_a: CCO:P0001415 ! regulation of sulfur amino acid metabolic process is_a: CCO:P0002745 ! regulation of hormone biosynthetic process [Term] id: CCO:P0000928 name: positive regulation of ethylene biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ethylene biosynthetic process." [GOC:tair_curators] xref: GO:0010365 is_a: CCO:P0000927 ! regulation of ethylene biosynthetic process is_a: CCO:P0001417 ! positive regulation of sulfur amino acid metabolic process is_a: CCO:P0002746 ! positive regulation of hormone biosynthetic process [Term] id: CCO:P0000929 name: negative regulation of ethylene biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ethylene biosynthetic process." [GOC:tair_curators] xref: GO:0010366 is_a: CCO:P0000927 ! regulation of ethylene biosynthetic process is_a: CCO:P0001416 ! negative regulation of sulfur amino acid metabolic process is_a: CCO:P0001611 ! negative regulation of hormone biosynthetic process [Term] id: CCO:P0000930 name: regulation of gibberellin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins." [GOC:tair_curators] synonym: "regulation of gibberellic acid biosynthetic process" NARROW [] xref: GO:0010371 is_a: CCO:P0001146 ! regulation of isoprenoid metabolic process is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000931 name: positive regulation of gibberellin biosynthetic process namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins." [GOC:tair_curators] synonym: "positive regulation of gibberellic acid biosynthetic process " NARROW [] xref: GO:0010372 is_a: CCO:P0000930 ! regulation of gibberellin biosynthetic process is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0002571 ! positive regulation of isoprenoid metabolic process [Term] id: CCO:P0000932 name: negative regulation of gibberellin biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins." [GOC:tair_curators] synonym: "negative regulation of gibberellic acid biosynthetic process" NARROW [] xref: GO:0010373 is_a: CCO:P0000930 ! regulation of gibberellin biosynthetic process is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0002570 ! negative regulation of isoprenoid metabolic process [Term] id: CCO:P0000933 name: regulation of chlorophyll biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors." [PMID:17291312] xref: GO:0010380 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process is_a: CCO:P0003056 ! regulation of cofactor metabolic process [Term] id: CCO:P0000934 name: regulation of brassinosteroid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids." [PMID:16857903] xref: GO:0010422 is_a: CCO:P0002962 ! regulation of steroid biosynthetic process [Term] id: CCO:P0000935 name: negative regulation of brassinosteroid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids." [PMID:16857903] xref: GO:0010423 is_a: CCO:P0000934 ! regulation of brassinosteroid biosynthetic process is_a: CCO:P0002623 ! negative regulation of steroid metabolic process [Term] id: CCO:P0000936 name: DNA methylation on cytosine within a CG sequence namespace: biological_process def: "The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule." [GOC:dph, GOC:tb, PMID:17239600] synonym: "cytosine methylation within a CG sequence" EXACT [GOC:dph, GOC:tb] xref: GO:0010424 is_a: CCO:P0001646 ! DNA methylation on cytosine [Term] id: CCO:P0000937 name: DNA methylation on cytosine within a CNG sequence namespace: biological_process def: "The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide." [GOC:dph, GOC:tb, PMID:17239600] synonym: "cytosine methylation within a CNG sequence" EXACT [GOC:dph, GOC:tb] xref: GO:0010425 is_a: CCO:P0001646 ! DNA methylation on cytosine [Term] id: CCO:P0000938 name: DNA methylation on cytosine within a CNN sequence namespace: biological_process def: "The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNN sequence in a DNA molecule. N stands for any nucleotide." [GOC:dph, GOC:tb, PMID:17239600] synonym: "cytosine methylation within a CNN sequence" EXACT [GOC:dph, GOC:tb] xref: GO:0010426 is_a: CCO:P0001646 ! DNA methylation on cytosine [Term] id: CCO:P0000939 name: regulation of glucosinolate biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae." [PMID:17420480] xref: GO:0010439 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0000940 name: regulation of cell fate commitment namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] xref: GO:0010453 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0000941 name: negative regulation of cell fate commitment namespace: biological_process def: "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] xref: GO:0010454 is_a: CCO:P0000940 ! regulation of cell fate commitment is_a: CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:P0000942 name: positive regulation of cell fate commitment namespace: biological_process def: "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] xref: GO:0010455 is_a: CCO:P0000940 ! regulation of cell fate commitment is_a: CCO:P0002411 ! positive regulation of cell differentiation [Term] id: CCO:P0000943 name: cell proliferation in dorsal spinal cord namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population." [GOC:dph, GOC:tb] xref: GO:0010456 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0000944 name: regulation of light-activated voltage-gated calcium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity." [GOC:dph, GOC:tb] xref: GO:0010462 is_a: CCO:P0002966 ! regulation of calcium-mediated signaling [Term] id: CCO:P0000945 name: mesenchymal cell proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] xref: GO:0010463 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0000946 name: regulation of mesenchymal cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] xref: GO:0010464 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0000945 ! mesenchymal cell proliferation [Term] id: CCO:P0000947 name: regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] subset: gosubset_prok xref: GO:0010468 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0055142 ! IL10_HUMAN relationship: has_participant CCO:B0055279 ! BMI1_HUMAN relationship: has_participant CCO:B0058421 ! SORT_HUMAN [Term] id: CCO:P0000948 name: gibberellin-mediated signaling namespace: biological_process def: "The series of molecular signals generated as a consequence of gibberellin stimulus." [PMID:17521411] xref: GO:0010476 is_a: CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:P0000949 name: epidermal cell division namespace: biological_process def: "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." [PMID:17450124] xref: GO:0010481 is_a: CCO:P0003077 ! cell division [Term] id: CCO:P0000950 name: regulation of epidermal cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." [PMID:17450124] xref: GO:0010482 is_a: CCO:P0003078 ! regulation of cell division relationship: regulates CCO:P0000949 ! epidermal cell division [Term] id: CCO:P0000951 name: maintenance of shoot apical meristem identity namespace: biological_process def: "Any process involved in maintaining the identity of the shoot apical meristem. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [PMID:17461786] xref: GO:0010492 is_a: CCO:P0000902 ! maintenance of meristem identity [Term] id: CCO:P0000952 name: long-distance posttranscriptional gene silencing namespace: biological_process def: "A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place." [GOC:dph, GOC:tb, PMID:11590235, PMID:17785412] synonym: "long-distance propagation of posttranscriptional gene silencing" EXACT [GOC:dph, GOC:tb] xref: GO:0010495 is_a: CCO:P0001123 ! posttranscriptional gene silencing [Term] id: CCO:P0000953 name: regulation of autophagy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb] xref: GO:0010506 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0054628 ! ULK1_HUMAN [Term] id: CCO:P0000954 name: negative regulation of autophagy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb] xref: GO:0010507 is_a: CCO:P0000953 ! regulation of autophagy is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0000955 name: positive regulation of autophagy namespace: biological_process def: "Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process by which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb] xref: GO:0010508 is_a: CCO:P0000953 ! regulation of autophagy is_a: CCO:P0002852 ! positive regulation of cellular process [Term] id: CCO:P0000956 name: regulation of acetyl-CoA biosynthetic process from pyruvate namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate." [GOC:dph, GOC:tb] xref: GO:0010510 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process is_a: CCO:P0003059 ! regulation of coenzyme metabolic process [Term] id: CCO:P0000957 name: regulation of phosphatidylinositol biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol." [GOC:dph, GOC:tb, GOC:vw] xref: GO:0010511 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0000958 name: negative regulation of phosphatidylinositol biosynthetic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol." [GOC:dph, GOC:tb, GOC:vw] xref: GO:0010512 is_a: CCO:P0000957 ! regulation of phosphatidylinositol biosynthetic process is_a: CCO:P0001405 ! negative regulation of cellular metabolic process relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN [Term] id: CCO:P0000959 name: positive regulation of phosphatidylinositol biosynthetic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol." [GOC:dph, GOC:tb, GOC:vw] xref: GO:0010513 is_a: CCO:P0000957 ! regulation of phosphatidylinositol biosynthetic process is_a: CCO:P0001406 ! positive regulation of cellular metabolic process [Term] id: CCO:P0000960 name: negative regulation of cellular response to nitrogen starvation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to nitrogen starvation." [GOC:dph, GOC:tb] xref: GO:0010516 is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0000961 name: regulation of transposition, RNA-mediated namespace: biological_process def: "Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate." [GOC:dph, GOC:tb] xref: GO:0010525 is_a: CCO:P0000964 ! regulation of transposition [Term] id: CCO:P0000962 name: negative regulation of transposition, RNA-mediated namespace: biological_process def: "Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate." [GOC:dph, GOC:tb] xref: GO:0010526 is_a: CCO:P0000961 ! regulation of transposition, RNA-mediated is_a: CCO:P0000965 ! negative regulation of transposition [Term] id: CCO:P0000963 name: positive regulation of transposition, RNA-mediated namespace: biological_process def: "Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate." [GOC:dph, GOC:tb] xref: GO:0010527 is_a: CCO:P0000961 ! regulation of transposition, RNA-mediated is_a: CCO:P0000966 ! positive regulation of transposition [Term] id: CCO:P0000964 name: regulation of transposition namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites." [GOC:dph, GOC:tb] subset: gosubset_prok xref: GO:0010528 is_a: CCO:P0000398 ! regulation of DNA recombination [Term] id: CCO:P0000965 name: negative regulation of transposition namespace: biological_process def: "Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites." [GOC:dph, GOC:tb] xref: GO:0010529 is_a: CCO:P0000964 ! regulation of transposition is_a: CCO:P0002607 ! negative regulation of DNA recombination [Term] id: CCO:P0000966 name: positive regulation of transposition namespace: biological_process def: "Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites." [GOC:dph, GOC:tb] xref: GO:0010530 is_a: CCO:P0000964 ! regulation of transposition is_a: CCO:P0002608 ! positive regulation of DNA recombination [Term] id: CCO:P0000967 name: activation of JAK1 kinase activity namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] synonym: "activation of JAK1 protein" EXACT [GOC:dph, GOC:tb] synonym: "tyrosine phosphorylation of JAK1 protein" RELATED [GOC:dph, GOC:tb] xref: GO:0010531 is_a: CCO:P0002129 ! activation of Janus kinase activity [Term] id: CCO:P0000968 name: regulation of activation of JAK1 kinase activity namespace: biological_process def: "Any process that modulates the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] synonym: "regulation of activation of JAK1 protein" EXACT [GOC:dph, GOC:tb] synonym: "regulation of tyrosine phosphorylation of JAK1 protein" RELATED [GOC:dph, GOC:tb] xref: GO:0010532 is_a: CCO:P0000969 ! regulation of activation of Janus kinase activity relationship: regulates CCO:P0000967 ! activation of JAK1 kinase activity [Term] id: CCO:P0000969 name: regulation of activation of Janus kinase activity namespace: biological_process def: "Any process that modulates the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] synonym: "regulation of activation of JAK protein" EXACT [GOC:dph, GOC:tb] synonym: "regulation of tyrosine phosphorylation of JAK protein" RELATED [GOC:dph, GOC:tb] xref: GO:0010533 xref: PMID:17190829 is_a: CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation relationship: regulates CCO:P0002129 ! activation of Janus kinase activity [Term] id: CCO:P0000970 name: regulation of activation of JAK2 kinase activity namespace: biological_process def: "Any process that modulates the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] synonym: "regulation of activation of JAK2 protein" EXACT [GOC:dph, GOC:tb] synonym: "regulation of tyrosine phosphorylation of JAK2 protein" RELATED [GOC:dph, GOC:tb] xref: GO:0010534 is_a: CCO:P0000969 ! regulation of activation of Janus kinase activity relationship: regulates CCO:P0002130 ! activation of JAK2 kinase activity [Term] id: CCO:P0000971 name: positive regulation of activation of JAK2 kinase activity namespace: biological_process def: "Any process that increase the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] synonym: "positive regulation of activation of JAK2 protein" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of tyrosine phosphorylation of JAK2 protein" RELATED [GOC:dph, GOC:tb] xref: GO:0010535 is_a: CCO:P0000970 ! regulation of activation of JAK2 kinase activity is_a: CCO:P0000972 ! positive regulation of activation of Janus kinase activity relationship: positively_regulates CCO:P0002130 ! activation of JAK2 kinase activity [Term] id: CCO:P0000972 name: positive regulation of activation of Janus kinase activity namespace: biological_process def: "Any process that increases the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] synonym: "positive regulation of activation of JAK protein" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of tyrosine phosphorylation of JAK protein" RELATED [GOC:dph, GOC:tb] xref: GO:0010536 is_a: CCO:P0000969 ! regulation of activation of Janus kinase activity is_a: CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: positively_regulates CCO:P0002129 ! activation of Janus kinase activity [Term] id: CCO:P0000973 name: positive regulation of activation of JAK1 kinase activity namespace: biological_process def: "Any process that increases the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it." [GOC:dph, GOC:tb, PMID:9135582] synonym: "positive regulation of activation of JAK1 protein" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of tyrosine phosphorylation of JAK1 protein" RELATED [GOC:dph, GOC:tb] xref: GO:0010537 is_a: CCO:P0000968 ! regulation of activation of JAK1 kinase activity is_a: CCO:P0000972 ! positive regulation of activation of Janus kinase activity relationship: positively_regulates CCO:P0000967 ! activation of JAK1 kinase activity [Term] id: CCO:P0000974 name: regulation of platelet activation namespace: biological_process def: "Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue." [GOC:dph, GOC:tb] xref: GO:0010543 is_a: CCO:P0002983 ! regulation of cell activation [Term] id: CCO:P0000975 name: negative regulation of platelet activation namespace: biological_process def: "Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue." [GOC:dph, GOC:tb] xref: GO:0010544 is_a: CCO:P0000974 ! regulation of platelet activation is_a: CCO:P0002984 ! negative regulation of cell activation relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN [Term] id: CCO:P0000976 name: regulation of thylakoid membrane disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly." [GOC:dph, GOC:tb, PMID:17416733] synonym: "regulation of thylakoid membrane degradation" EXACT [GOC:dph, GOC:tb] xref: GO:0010548 is_a: CCO:P0000977 ! regulation of membrane disassembly is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis [Term] id: CCO:P0000977 name: regulation of membrane disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of membrane disassembly." [GOC:dph, GOC:tb] xref: GO:0010549 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0000978 name: regulation of PSII associated light-harvesting complex II catabolic process namespace: biological_process def: "Any process that modulates the catabolism of one or more components of the light-harvesting complex of photosystem II." [GOC:dph, GOC:tb] synonym: "regulation of LHCII catabolism" EXACT [GOC:dph, GOC:tb, PMID:17416733] synonym: "regulation of LHCII degradation" EXACT [PMID:17416733] xref: GO:0010550 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0001572 ! regulation of cellular protein metabolic process [Term] id: CCO:P0000979 name: regulation of specific transcription from RNA polymerase II promoter namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter." [GOC:dph, GOC:tb] xref: GO:0010551 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter is_a: CCO:P0001644 ! regulation of gene-specific transcription relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0036934 ! HNF4A_HUMAN relationship: has_participant CCO:B0055146 ! USF1_HUMAN [Term] id: CCO:P0000980 name: positive regulation of specific transcription from RNA polymerase II promoter namespace: biological_process def: "Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter." [GOC:dph, GOC:tb] xref: GO:0010552 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter is_a: CCO:P0002172 ! positive regulation of gene-specific transcription is_a: CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0036934 ! HNF4A_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: has_participant CCO:B0054883 ! PA21B_HUMAN relationship: has_participant CCO:B0055146 ! USF1_HUMAN relationship: has_participant CCO:B0055165 ! GATA2_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN [Term] id: CCO:P0000981 name: negative regulation of specific transcription from RNA polymerase II promoter namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific gene or set of genes by RNA polymerase II (Pol II), originating at a Pol II-specific promoter." [GOC:dph, GOC:tb] xref: GO:0010553 is_a: CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter is_a: CCO:P0001643 ! negative regulation of gene-specific transcription relationship: has_participant CCO:B0039142 ! FOXJ1_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN [Term] id: CCO:P0000982 name: regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues other than as a moiety of nucleic acid; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] subset: gosubset_prok xref: GO:0010559 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0000983 name: positive regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues other than as a moiety of nucleic acid; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] xref: GO:0010560 is_a: CCO:P0000982 ! regulation of glycoprotein biosynthetic process is_a: CCO:P0001406 ! positive regulation of cellular metabolic process [Term] id: CCO:P0000984 name: negative regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues other than as a moiety of nucleic acid; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] xref: GO:0010561 is_a: CCO:P0000982 ! regulation of glycoprotein biosynthetic process is_a: CCO:P0001405 ! negative regulation of cellular metabolic process [Term] id: CCO:P0000985 name: positive regulation of phosphorus metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] xref: GO:0010562 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0003053 ! regulation of phosphorus metabolic process [Term] id: CCO:P0000986 name: negative regulation of phosphorus metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] xref: GO:0010563 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0003053 ! regulation of phosphorus metabolic process [Term] id: CCO:P0000987 name: regulation of ketone metabolic process namespace: biological_process def: "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:dph, GOC:tb] xref: GO:0010565 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0000988 name: regulation of ketone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] xref: GO:0010566 is_a: CCO:P0000987 ! regulation of ketone metabolic process is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000989 name: regulation of ketone catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] xref: GO:0010567 is_a: CCO:P0000987 ! regulation of ketone metabolic process is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0000990 name: regulation of budding cell apical growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding." [GOC:dph, GOC:jp, GOC:tb, PMID:17417630] xref: GO:0010568 is_a: CCO:P0002955 ! regulation of cellular process relationship: regulates CCO:P0000703 ! budding cell apical bud growth [Term] id: CCO:P0000991 name: regulation of double-strand break repair via homologous recombination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences." [GOC:dph, GOC:jp, GOC:tb] xref: GO:0010569 is_a: CCO:P0000398 ! regulation of DNA recombination is_a: CCO:P0000643 ! regulation of DNA repair [Term] id: CCO:P0000992 name: positive regulation of platelet activation namespace: biological_process def: "Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue." [GOC:dph, GOC:sl, GOC:tb] xref: GO:0010572 is_a: CCO:P0000974 ! regulation of platelet activation is_a: CCO:P0002985 ! positive regulation of cell activation [Term] id: CCO:P0000993 name: regulation of adenylate cyclase activity involved in G-protein signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adenylate cyclase activity that is an integral part of the series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, resulting in a subsequent change in the concentration of cyclic AMP." [GOC:dph, GOC:tb] xref: GO:0010578 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000728 ! G-protein signaling, coupled to cAMP nucleotide second messenger [Term] id: CCO:P0000994 name: positive regulation of adenylate cyclase activity involved in G-protein signaling namespace: biological_process def: "Any process that increases the frequency, rate or extent of adenylate cyclase activity that is an integral part of the series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, resulting in a subsequent change in the concentration of cyclic AMP." [GOC:dph, GOC:tb] xref: GO:0010579 is_a: CCO:P0000993 ! regulation of adenylate cyclase activity involved in G-protein signaling relationship: part_of CCO:P0000729 ! G-protein signaling, adenylate cyclase activating pathway [Term] id: CCO:P0000995 name: activation of adenylate cyclase activity involved in G-protein signaling namespace: biological_process def: "Any process that initiates the activity of an inactive adenylate cyclase that is an integral part of the series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, resulting in a subsequent change in the concentration of cyclic AMP." [GOC:dph, GOC:tb] xref: GO:0010580 is_a: CCO:P0000994 ! positive regulation of adenylate cyclase activity involved in G-protein signaling [Term] id: CCO:P0000996 name: regulation of starch biosynthetic process namespace: biological_process def: "An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch." [GOC:tb] xref: GO:0010581 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0000997 name: regulation of cell separation during cytokinesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the process of physically separating progeny cells during cytokinesis; this may involve enzymatic digestion of septum or cell wall components." [GOC:dph, GOC:tb] xref: GO:0010590 is_a: CCO:P0001734 ! regulation of cytokinetic process relationship: regulates CCO:P0000456 ! cell separation during cytokinesis [Term] id: CCO:P0000998 name: regulation of lamellipodium biogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell." [GOC:dph, GOC:tb] xref: GO:0010591 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis [Term] id: CCO:P0000999 name: positive regulation of lamellipodium biogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell." [GOC:dph, GOC:tb] xref: GO:0010592 is_a: CCO:P0000998 ! regulation of lamellipodium biogenesis is_a: CCO:P0001423 ! positive regulation of cell projection organization and biogenesis [Term] id: CCO:P0001000 name: negative regulation of lamellipodium biogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell." [GOC:dph, GOC:tb] xref: GO:0010593 is_a: CCO:P0000998 ! regulation of lamellipodium biogenesis is_a: CCO:P0001422 ! negative regulation of cell projection organization and biogenesis [Term] id: CCO:P0001001 name: regulation of endothelial cell migration namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the orderly movement of endothelial cells into the extracellular matrix to form an endothelium." [GOC:dph, GOC:tb] xref: GO:0010594 is_a: CCO:P0001257 ! regulation of cell migration [Term] id: CCO:P0001002 name: positive regulation of endothelial cell migration namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the orderly movement of endothelial cells into the extracellular matrix to form an endothelium." [GOC:dph, GOC:tb] xref: GO:0010595 is_a: CCO:P0001001 ! regulation of endothelial cell migration is_a: CCO:P0001258 ! positive regulation of cell migration [Term] id: CCO:P0001003 name: negative regulation of endothelial cell migration namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the orderly movement of endothelial cells into the extracellular matrix to form an endothelium." [GOC:dph, GOC:tb] xref: GO:0010596 is_a: CCO:P0001001 ! regulation of endothelial cell migration is_a: CCO:P0001259 ! negative regulation of cell migration relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: has_participant CCO:B0059181 ! GDF2_HUMAN [Term] id: CCO:P0001004 name: RNA interference, production of lsiRNA namespace: biological_process def: "Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions." [PMID:18003861] xref: GO:0010599 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001122 ! RNA interference [Term] id: CCO:P0001005 name: regulation of auxin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth." [PMID:18287041] xref: GO:0010600 is_a: CCO:P0002745 ! regulation of hormone biosynthetic process [Term] id: CCO:P0001006 name: positive regulation of auxin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth." [PMID:18287041] xref: GO:0010601 is_a: CCO:P0001005 ! regulation of auxin biosynthetic process is_a: CCO:P0002746 ! positive regulation of hormone biosynthetic process [Term] id: CCO:P0001007 name: regulation of 1-aminocyclopropane-1-carboxylate metabolic process namespace: biological_process def: "Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants." [PMID:18055613] xref: GO:0010602 is_a: CCO:P0001608 ! regulation of hormone metabolic process [Term] id: CCO:P0001008 name: posttranscriptional regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." [GOC:dph, GOC:tb] xref: GO:0010608 is_a: CCO:P0000947 ! regulation of gene expression [Term] id: CCO:P0001009 name: posttranscriptional regulation of gene expression by mRNA localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell." [GOC:dph, GOC:tb] xref: GO:0010609 is_a: CCO:P0001008 ! posttranscriptional regulation of gene expression [Term] id: CCO:P0001010 name: regulation of mRNA stability involved in response to stress namespace: biological_process def: "Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance." [GOC:dph, GOC:tb] xref: GO:0010610 is_a: CCO:P0002223 ! regulation of mRNA stability [Term] id: CCO:P0001011 name: activation of adenylate cyclase activity involved in G-protein signaling by glucose namespace: biological_process def: "Any glucose-triggered process that initiates the activity of an inactive adenylate cyclase that is an integral part of the series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, resulting in a subsequent change in the concentration of cyclic AMP." [GOC:dph, GOC:tb] synonym: "activation of adenylate cyclase activity by glucose involved in G-protein signaling" EXACT [GOC:dph, GOC:tb] xref: GO:0010619 is_a: CCO:P0000995 ! activation of adenylate cyclase activity involved in G-protein signaling [Term] id: CCO:P0001012 name: negative regulation of transcription by transcription factor catabolism namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a transcription factor." [GOC:dph, GOC:tb] xref: GO:0010620 is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:P0001013 name: negative regulation of transcription by transcription factor localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor." [GOC:dph, GOC:tb] xref: GO:0010621 is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:P0001014 name: regulation of Schwann cell proliferation namespace: biological_process def: "Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] xref: GO:0010624 is_a: CCO:P0003297 ! regulation of glial cell proliferation relationship: regulates CCO:P0001057 ! Schwann cell proliferation [Term] id: CCO:P0001015 name: positive regulation of Schwann cell proliferation namespace: biological_process def: "Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] xref: GO:0010625 is_a: CCO:P0001014 ! regulation of Schwann cell proliferation is_a: CCO:P0003298 ! positive regulation of glial cell proliferation relationship: positively_regulates CCO:P0001057 ! Schwann cell proliferation [Term] id: CCO:P0001016 name: negative regulation of Schwann cell proliferation namespace: biological_process def: "Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] xref: GO:0010626 is_a: CCO:P0001014 ! regulation of Schwann cell proliferation is_a: CCO:P0003299 ! negative regulation of glial cell proliferation relationship: negatively_regulates CCO:P0001057 ! Schwann cell proliferation [Term] id: CCO:P0001017 name: regulation of protein kinase cascade namespace: biological_process def: "Any process that modulates a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound." [GOC:dph, GOC:tb] xref: GO:0010627 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0000767 ! protein kinase cascade [Term] id: CCO:P0001018 name: positive regulation of gene expression namespace: biological_process def: "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] xref: GO:0010628 is_a: CCO:P0000947 ! regulation of gene expression [Term] id: CCO:P0001019 name: negative regulation of gene expression namespace: biological_process def: "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] xref: GO:0010629 is_a: CCO:P0000947 ! regulation of gene expression [Term] id: CCO:P0001020 name: regulation of transcription, start site selection namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template." [GOC:dph, GOC:tb] xref: GO:0010630 is_a: CCO:P0002369 ! regulation of transcription [Term] id: CCO:P0001021 name: regulation of epithelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell migration." [GOC:dph, GOC:tb] xref: GO:0010632 is_a: CCO:P0001257 ! regulation of cell migration [Term] id: CCO:P0001022 name: negative regulation of epithelial cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell migration." [GOC:dph, GOC:tb] xref: GO:0010633 is_a: CCO:P0001021 ! regulation of epithelial cell migration is_a: CCO:P0001259 ! negative regulation of cell migration [Term] id: CCO:P0001023 name: positive regulation of epithelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." [GOC:dph, GOC:tb] xref: GO:0010634 is_a: CCO:P0001021 ! regulation of epithelial cell migration is_a: CCO:P0001258 ! positive regulation of cell migration [Term] id: CCO:P0001024 name: regulation of mitochondrial fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." [GOC:dph, GOC:tb] xref: GO:0010635 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis [Term] id: CCO:P0001025 name: positive regulation of mitochondrial fusion namespace: biological_process def: "Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." [GOC:dph, GOC:tb] xref: GO:0010636 is_a: CCO:P0001024 ! regulation of mitochondrial fusion is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis [Term] id: CCO:P0001026 name: negative regulation of mitochondrial fusion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment." [GOC:dph, GOC:tb] xref: GO:0010637 is_a: CCO:P0001024 ! regulation of mitochondrial fusion is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis [Term] id: CCO:P0001027 name: positive regulation of organelle organization and biogenesis namespace: biological_process def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] xref: GO:0010638 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis [Term] id: CCO:P0001028 name: negative regulation of organelle organization and biogenesis namespace: biological_process def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] xref: GO:0010639 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis [Term] id: CCO:P0001029 name: regulation of platelet-derived growth factor receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway." [GOC:dph, GOC:hjd, GOC:tb] xref: GO:0010640 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway [Term] id: CCO:P0001030 name: positive regulation of platelet-derived growth factor receptor signaling pathway namespace: biological_process def: "Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway." [GOC:dph, GOC:hjd, GOC:tb] xref: GO:0010641 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001029 ! regulation of platelet-derived growth factor receptor signaling pathway relationship: positively_regulates CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway [Term] id: CCO:P0001031 name: negative regulation of platelet-derived growth factor receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway." [GOC:dph, GOC:hjd, GOC:tb] xref: GO:0010642 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001029 ! regulation of platelet-derived growth factor receptor signaling pathway relationship: negatively_regulates CCO:P0002754 ! platelet-derived growth factor receptor signaling pathway [Term] id: CCO:P0001032 name: regulation of cell communication by chemical coupling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kva, GOC:tb] xref: GO:0010645 is_a: CCO:P0001033 ! regulation of cell communication [Term] id: CCO:P0001033 name: regulation of cell communication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] xref: GO:0010646 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0001034 name: positive regulation of cell communication namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] xref: GO:0010647 is_a: CCO:P0001033 ! regulation of cell communication is_a: CCO:P0002852 ! positive regulation of cellular process [Term] id: CCO:P0001035 name: negative regulation of cell communication namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] xref: GO:0010648 is_a: CCO:P0001033 ! regulation of cell communication is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0001036 name: regulation of cell communication by electrical coupling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kva, GOC:tb] xref: GO:0010649 is_a: CCO:P0001033 ! regulation of cell communication [Term] id: CCO:P0001037 name: positive regulation of cell communication by electrical coupling namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kva, GOC:tb] xref: GO:0010650 is_a: CCO:P0001034 ! positive regulation of cell communication is_a: CCO:P0001036 ! regulation of cell communication by electrical coupling [Term] id: CCO:P0001038 name: negative regulation of cell communication by electrical coupling namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kva, GOC:tb] xref: GO:0010651 is_a: CCO:P0001035 ! negative regulation of cell communication is_a: CCO:P0001036 ! regulation of cell communication by electrical coupling [Term] id: CCO:P0001039 name: positive regulation of cell communication by chemical coupling namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kva, GOC:tb] xref: GO:0010652 is_a: CCO:P0001032 ! regulation of cell communication by chemical coupling is_a: CCO:P0001034 ! positive regulation of cell communication [Term] id: CCO:P0001040 name: negative regulation of cell communication by chemical coupling namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels." [GOC:dph, GOC:kva, GOC:tb] xref: GO:0010653 is_a: CCO:P0001032 ! regulation of cell communication by chemical coupling is_a: CCO:P0001035 ! negative regulation of cell communication [Term] id: CCO:P0001041 name: negative regulation of muscle cell apoptosis namespace: biological_process def: "Any process that decreases the rate or frequency of muscle cell apoptosis. Muscle cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:tb] xref: GO:0010656 is_a: CCO:P0001042 ! regulation of muscle cell apoptosis [Term] id: CCO:P0001042 name: regulation of muscle cell apoptosis namespace: biological_process def: "Any process that modulates the rate or frequency of muscle cell apoptosis. Muscle cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:tb] xref: GO:0010660 is_a: CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:P0001043 name: positive regulation of muscle cell apoptosis namespace: biological_process def: "Any process that increases the rate or frequency of muscle cell apoptosis. Muscle cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:tb] xref: GO:0010661 is_a: CCO:P0001042 ! regulation of muscle cell apoptosis [Term] id: CCO:P0001044 name: regulation of striated muscle cell apoptosis namespace: biological_process def: "Any process that modulates the rate or extent of striated muscle cell apoptosis. Striated muscle cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:tb] xref: GO:0010662 is_a: CCO:P0001042 ! regulation of muscle cell apoptosis [Term] id: CCO:P0001045 name: positive regulation of striated muscle cell apoptosis namespace: biological_process def: "Any process that increases the rate or extent of striated muscle cell apoptosis. Striated muscle cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:tb] xref: GO:0010663 is_a: CCO:P0001043 ! positive regulation of muscle cell apoptosis is_a: CCO:P0001044 ! regulation of striated muscle cell apoptosis [Term] id: CCO:P0001046 name: negative regulation of striated muscle cell apoptosis namespace: biological_process def: "Any process that increases the rate or extent of striated muscle cell apoptosis. Striated muscle cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:rl, GOC:tb] synonym: "down regulation of striated muscle cell apoptosis " EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of striated muscle cell apoptosis " NARROW [GOC:dph, GOC:rl, GOC:tb] xref: GO:0010664 is_a: CCO:P0001041 ! negative regulation of muscle cell apoptosis is_a: CCO:P0001044 ! regulation of striated muscle cell apoptosis [Term] id: CCO:P0001047 name: regulation of cardiac muscle cell apoptosis namespace: biological_process def: "Any process that modulates the rate or extent of cardiac cell apoptosis. Cardiac cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:tb] xref: GO:0010665 is_a: CCO:P0001044 ! regulation of striated muscle cell apoptosis [Term] id: CCO:P0001048 name: positive regulation of cardiac muscle cell apoptosis namespace: biological_process def: "Any process that increases the rate or extent of cardiac cell apoptosis. Cardiac cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:tb] xref: GO:0010666 is_a: CCO:P0001045 ! positive regulation of striated muscle cell apoptosis is_a: CCO:P0001047 ! regulation of cardiac muscle cell apoptosis [Term] id: CCO:P0001049 name: negative regulation of cardiac muscle cell apoptosis namespace: biological_process def: "Any process that decreases the rate or extent of cardiac cell apoptosis. Cardiac cell apoptosis is a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:rl, GOC:tb] synonym: "down regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of cardiac muscle cell apoptosis " NARROW [GOC:dph, GOC:rl, GOC:tb] xref: GO:0010667 is_a: CCO:P0001046 ! negative regulation of striated muscle cell apoptosis is_a: CCO:P0001047 ! regulation of cardiac muscle cell apoptosis [Term] id: CCO:P0001050 name: induction of programmed cell death namespace: biological_process def: "A process which directly activates any of the steps required for programmed cell death." [GOC:lr] xref: GO:0012502 is_a: CCO:P0002150 ! positive regulation of programmed cell death [Term] id: CCO:P0001051 name: induction of non-apoptotic programmed cell death namespace: biological_process def: "A process which directly activates any of the steps required for non-apoptotic programmed cell death." [GOC:lr] synonym: "induction of nonapoptotic programmed cell death" EXACT [] xref: GO:0012503 is_a: CCO:P0001050 ! induction of programmed cell death is_a: CCO:P0002153 ! positive regulation of non-apoptotic programmed cell death [Term] id: CCO:P0001052 name: induction of non-apoptotic programmed cell death by other organism namespace: biological_process def: "A process which directly activates any of the steps required for non-apoptotic programmed cell death in another organism." [GOC:curators, GOC:mtg_pamgo_17jul06] subset: gosubset_prok xref: GO:0012504 is_a: CCO:P0001051 ! induction of non-apoptotic programmed cell death is_a: CCO:P0003186 ! induction by symbiont of host programmed cell death is_a: CCO:P0003192 ! positive regulation by symbiont of host non-apoptotic programmed cell death is_a: CCO:P0003207 ! induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0001053 name: regulation of microglia differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell." [GOC:ef] synonym: "regulation of microglial cell differentiation" EXACT [] xref: GO:0014006 is_a: CCO:P0002493 ! regulation of glial cell differentiation [Term] id: CCO:P0001054 name: negative regulation of microglia differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell." [GOC:ef] synonym: "down regulation of microglia differentiation" EXACT [] synonym: "down-regulation of microglia differentiation" EXACT [] synonym: "downregulation of microglia differentiation" EXACT [] synonym: "inhibition of microglia differentiation" NARROW [] synonym: "negative regulation of microglial cell differentiation" EXACT [] xref: GO:0014007 is_a: CCO:P0001053 ! regulation of microglia differentiation is_a: CCO:P0002494 ! negative regulation of glial cell differentiation [Term] id: CCO:P0001055 name: positive regulation of microglia differentiation namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process whereby a relatively unspecialized cell acquires specialized features of a microglial cell." [GOC:ef] synonym: "activation of microglia differentiation" NARROW [] synonym: "positive regulation of microglial cell differentiation" EXACT [] synonym: "stimulation of microglia differentiation" NARROW [] synonym: "up regulation of microglia differentiation" EXACT [] synonym: "up-regulation of microglia differentiation" EXACT [] synonym: "upregulation of microglia differentiation" EXACT [] xref: GO:0014008 is_a: CCO:P0001053 ! regulation of microglia differentiation is_a: CCO:P0002495 ! positive regulation of glial cell differentiation [Term] id: CCO:P0001056 name: glial cell proliferation namespace: biological_process def: "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." [GOC:ef, ISBN:0878932585] synonym: "glia proliferation" EXACT [] xref: GO:0014009 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001057 name: Schwann cell proliferation namespace: biological_process def: "The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:ef, ISBN:0878932585] xref: GO:0014010 is_a: CCO:P0001056 ! glial cell proliferation relationship: has_participant CCO:B0001592 ! MERL_HUMAN [Term] id: CCO:P0001058 name: Schwann cell proliferation involved in axon regeneration namespace: biological_process def: "The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system." [GOC:ef, ISBN:0878932585] xref: GO:0014011 is_a: CCO:P0001057 ! Schwann cell proliferation [Term] id: CCO:P0001059 name: regulation of gliogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] xref: GO:0014013 is_a: CCO:P0002945 ! regulation of neurogenesis [Term] id: CCO:P0001060 name: negative regulation of gliogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "down regulation of gliogenesis" EXACT [] synonym: "down-regulation of gliogenesis" EXACT [] synonym: "downregulation of gliogenesis" EXACT [] synonym: "inhibition of gliogenesis" NARROW [] xref: GO:0014014 is_a: CCO:P0001059 ! regulation of gliogenesis is_a: CCO:P0002946 ! negative regulation of neurogenesis [Term] id: CCO:P0001061 name: positive regulation of gliogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "activation of gliogenesis" NARROW [] synonym: "stimulation of gliogenesis" NARROW [] synonym: "up regulation of gliogenesis" EXACT [] synonym: "up-regulation of gliogenesis" EXACT [] synonym: "upregulation of gliogenesis" EXACT [] xref: GO:0014015 is_a: CCO:P0001059 ! regulation of gliogenesis is_a: CCO:P0002947 ! positive regulation of neurogenesis [Term] id: CCO:P0001062 name: neural crest formation namespace: biological_process def: "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:dh, GOC:ef] xref: GO:0014029 is_a: CCO:P0000480 ! epithelial to mesenchymal transition [Term] id: CCO:P0001063 name: regulation of Schwann cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] xref: GO:0014038 is_a: CCO:P0002493 ! regulation of glial cell differentiation [Term] id: CCO:P0001064 name: negative regulation of Schwann cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] synonym: "down regulation of Schwann cell differentiation" EXACT [] synonym: "down-regulation of Schwann cell differentiation" EXACT [] synonym: "downregulation of Schwann cell differentiation" EXACT [] synonym: "inhibition of Schwann cell differentiation" NARROW [] xref: GO:0014039 is_a: CCO:P0001063 ! regulation of Schwann cell differentiation is_a: CCO:P0002494 ! negative regulation of glial cell differentiation [Term] id: CCO:P0001065 name: positive regulation of Schwann cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] synonym: "activation of Schwann cell differentiation" NARROW [] synonym: "stimulation of Schwann cell differentiation" NARROW [] synonym: "up regulation of Schwann cell differentiation" EXACT [] synonym: "up-regulation of Schwann cell differentiation" EXACT [] synonym: "upregulation of Schwann cell differentiation" EXACT [] xref: GO:0014040 is_a: CCO:P0001063 ! regulation of Schwann cell differentiation is_a: CCO:P0002495 ! positive regulation of glial cell differentiation [Term] id: CCO:P0001066 name: regulation of neuron maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." [GOC:ef] xref: GO:0014041 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0001067 name: positive regulation of neuron maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "activation of neuron maturation" NARROW [] synonym: "stimulation of neuron maturation" NARROW [] synonym: "up regulation of neuron maturation" EXACT [] synonym: "up-regulation of neuron maturation" EXACT [] synonym: "upregulation of neuron maturation" EXACT [] xref: GO:0014042 is_a: CCO:P0001066 ! regulation of neuron maturation is_a: CCO:P0002852 ! positive regulation of cellular process [Term] id: CCO:P0001068 name: negative regulation of neuron maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "down regulation of neuron maturation" EXACT [] synonym: "down-regulation of neuron maturation" EXACT [] synonym: "downregulation of neuron maturation" EXACT [] synonym: "inhibition of neuron maturation" NARROW [] xref: GO:0014043 is_a: CCO:P0001066 ! regulation of neuron maturation is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0001069 name: regulation of glutamate secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of glutamate." [GOC:ef] xref: GO:0014048 is_a: CCO:P0002749 ! regulation of neurotransmitter secretion [Term] id: CCO:P0001070 name: positive regulation of glutamate secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of glutamate." [GOC:ef] synonym: "activation of glutamate secretion" NARROW [] synonym: "stimulation of glutamate secretion" NARROW [] synonym: "up regulation of glutamate secretion" EXACT [] synonym: "up-regulation of glutamate secretion" EXACT [] synonym: "upregulation of glutamate secretion" EXACT [] xref: GO:0014049 is_a: CCO:P0000510 ! positive regulation of neurotransmitter secretion is_a: CCO:P0001069 ! regulation of glutamate secretion relationship: has_participant CCO:B0033431 ! NMDE2_HUMAN [Term] id: CCO:P0001071 name: negative regulation of glutamate secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of glutamate." [GOC:ef] synonym: "down regulation of glutamate secretion" EXACT [] synonym: "down-regulation of glutamate secretion" EXACT [] synonym: "downregulation of glutamate secretion" EXACT [] synonym: "inhibition of glutamate secretion" NARROW [] xref: GO:0014050 is_a: CCO:P0001069 ! regulation of glutamate secretion is_a: CCO:P0002750 ! negative regulation of neurotransmitter secretion [Term] id: CCO:P0001072 name: regulation of gamma-aminobutyric acid secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." [GOC:ef] synonym: "regulation of GABA secretion" EXACT [] xref: GO:0014052 is_a: CCO:P0002749 ! regulation of neurotransmitter secretion [Term] id: CCO:P0001073 name: negative regulation of gamma-aminobutyric acid secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." [GOC:ef] synonym: "down regulation of gamma-aminobutyric acid secretion" EXACT [] synonym: "down-regulation of gamma-aminobutyric acid secretion" EXACT [] synonym: "downregulation of gamma-aminobutyric acid secretion" EXACT [] synonym: "inhibition of gamma-aminobutyric acid secretion" NARROW [] synonym: "negative regulation of GABA secretion" EXACT [] xref: GO:0014053 is_a: CCO:P0001072 ! regulation of gamma-aminobutyric acid secretion is_a: CCO:P0002750 ! negative regulation of neurotransmitter secretion [Term] id: CCO:P0001074 name: positive regulation of gamma-aminobutyric acid secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." [GOC:ef] synonym: "activation of gamma-aminobutyric acid secretion" NARROW [] synonym: "positive regulation of GABA secretion" EXACT [] synonym: "stimulation of gamma-aminobutyric acid secretion" NARROW [] synonym: "up regulation of gamma-aminobutyric acid secretion" EXACT [] synonym: "up-regulation of gamma-aminobutyric acid secretion" EXACT [] synonym: "upregulation of gamma-aminobutyric acid secretion" EXACT [] xref: GO:0014054 is_a: CCO:P0000510 ! positive regulation of neurotransmitter secretion is_a: CCO:P0001072 ! regulation of gamma-aminobutyric acid secretion [Term] id: CCO:P0001075 name: regulation of acetylcholine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] xref: GO:0014056 is_a: CCO:P0002749 ! regulation of neurotransmitter secretion relationship: has_participant CCO:B0032804 ! ACHA3_HUMAN [Term] id: CCO:P0001076 name: positive regulation of acetylcholine secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "activation of acetylcholine secretion" NARROW [] synonym: "stimulation of acetylcholine secretion" NARROW [] synonym: "up regulation of acetylcholine secretion" EXACT [] synonym: "up-regulation of acetylcholine secretion" EXACT [] synonym: "upregulation of acetylcholine secretion" EXACT [] xref: GO:0014057 is_a: CCO:P0000510 ! positive regulation of neurotransmitter secretion is_a: CCO:P0001075 ! regulation of acetylcholine secretion [Term] id: CCO:P0001077 name: negative regulation of acetylcholine secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "down regulation of acetylcholine secretion" EXACT [] synonym: "down-regulation of acetylcholine secretion" EXACT [] synonym: "downregulation of acetylcholine secretion" EXACT [] synonym: "inhibition of acetylcholine secretion" NARROW [] xref: GO:0014058 is_a: CCO:P0001075 ! regulation of acetylcholine secretion is_a: CCO:P0002750 ! negative regulation of neurotransmitter secretion [Term] id: CCO:P0001078 name: regulation of dopamine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of dopamine." [GOC:ef] xref: GO:0014059 is_a: CCO:P0002744 ! regulation of hormone secretion is_a: CCO:P0002909 ! regulation of catecholamine secretion relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN relationship: has_participant CCO:B0055198 ! 5HT2A_HUMAN relationship: has_participant CCO:B0055368 ! ACHA4_HUMAN [Term] id: CCO:P0001079 name: regulation of epinephrine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of epinephrine." [GOC:ef] synonym: "regulation of adrenaline secretion" EXACT [] xref: GO:0014060 is_a: CCO:P0002744 ! regulation of hormone secretion is_a: CCO:P0002909 ! regulation of catecholamine secretion [Term] id: CCO:P0001080 name: regulation of norepinephrine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." [GOC:ef] synonym: "regulation of noradrenaline secretion" EXACT [] xref: GO:0014061 is_a: CCO:P0002744 ! regulation of hormone secretion is_a: CCO:P0002909 ! regulation of catecholamine secretion relationship: has_participant CCO:B0055310 ! ACHA7_HUMAN [Term] id: CCO:P0001081 name: regulation of serotonin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] xref: GO:0014062 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0001082 name: negative regulation of serotonin secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "down regulation of serotonin secretion" EXACT [] synonym: "down-regulation of serotonin secretion" EXACT [] synonym: "downregulation of serotonin secretion" EXACT [] synonym: "inhibition of serotonin secretion" NARROW [] xref: GO:0014063 is_a: CCO:P0001081 ! regulation of serotonin secretion is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0001083 name: positive regulation of serotonin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "activation of serotonin secretion" NARROW [] synonym: "stimulation of serotonin secretion" NARROW [] synonym: "up regulation of serotonin secretion" EXACT [] synonym: "up-regulation of serotonin secretion" EXACT [] synonym: "upregulation of serotonin secretion" EXACT [] xref: GO:0014064 is_a: CCO:P0001081 ! regulation of serotonin secretion is_a: CCO:P0002852 ! positive regulation of cellular process [Term] id: CCO:P0001084 name: phosphoinositide 3-kinase cascade namespace: biological_process def: "A series of reactions, mediated by the intracellular phosphoinositide 3-kinase (PI3K). PI3K cascades lie downstream of many cell surface receptor linked signaling pathways and regulate numerous cellular functions." [GOC:ef, http://en.wikipedia.org "Wikipedia", http://www.biocarta.com] synonym: "PI 3-kinase cascade" EXACT [] synonym: "PI3K cascade" EXACT [] xref: GO:0014065 is_a: CCO:P0000767 ! protein kinase cascade relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN [Term] id: CCO:P0001085 name: regulation of phosphoinositide 3-kinase cascade namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphoinositide 3-kinase cascade." [GOC:ef] synonym: "regulation of PI 3-kinase cascade" RELATED [] synonym: "regulation of PI3K cascade" EXACT [] xref: GO:0014066 is_a: CCO:P0001017 ! regulation of protein kinase cascade relationship: regulates CCO:P0001084 ! phosphoinositide 3-kinase cascade [Term] id: CCO:P0001086 name: negative regulation of phosphoinositide 3-kinase cascade namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by the phosphoinositide 3-kinase cascade." [GOC:ef] synonym: "down regulation of phosphoinositide 3-kinase cascade" EXACT [] synonym: "down-regulation of phosphoinositide 3-kinase cascade" EXACT [] synonym: "downregulation of phosphoinositide 3-kinase cascade" EXACT [] synonym: "inhibition of phosphoinositide 3-kinase cascade" NARROW [] synonym: "negative regulation of PI 3-kinase cascade" EXACT [] synonym: "negative regulation of PI3K cascade" EXACT [] xref: GO:0014067 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001085 ! regulation of phosphoinositide 3-kinase cascade relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: negatively_regulates CCO:P0001084 ! phosphoinositide 3-kinase cascade [Term] id: CCO:P0001087 name: positive regulation of phosphoinositide 3-kinase cascade namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphoinositide 3-kinase cascade." [GOC:ef] synonym: "activation of phosphoinositide 3-kinase cascade" NARROW [] synonym: "positive regulation of PI 3-kinase cascade" EXACT [] synonym: "positive regulation of PI3K cascade" EXACT [] synonym: "stimulation of phosphoinositide 3-kinase cascade" NARROW [] synonym: "up regulation of phosphoinositide 3-kinase cascade" EXACT [] synonym: "up-regulation of phosphoinositide 3-kinase cascade" EXACT [] synonym: "upregulation of phosphoinositide 3-kinase cascade" EXACT [] xref: GO:0014068 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001085 ! regulation of phosphoinositide 3-kinase cascade relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: positively_regulates CCO:P0001084 ! phosphoinositide 3-kinase cascade [Term] id: CCO:P0001088 name: satellite cell asymmetric division involved in skeletal muscle regeneration namespace: biological_process def: "Satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fibre, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:mtg_muscle] xref: GO:0014716 is_a: CCO:P0001092 ! satellite cell asymmetric division relationship: part_of CCO:P0001093 ! satellite cell maintenance involved in skeletal muscle regeneration [Term] id: CCO:P0001089 name: regulation of satellite cell activation involved in skeletal muscle regeneration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate." [GOC:mtg_muscle] xref: GO:0014717 is_a: CCO:P0002983 ! regulation of cell activation [Term] id: CCO:P0001090 name: positive regulation of satellite cell activation involved in skeletal muscle regeneration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate." [GOC:mtg_muscle] xref: GO:0014718 is_a: CCO:P0001089 ! regulation of satellite cell activation involved in skeletal muscle regeneration is_a: CCO:P0002985 ! positive regulation of cell activation [Term] id: CCO:P0001091 name: initiation of satellite cell activation by growth factor signalling, involved in skeletal muscle regeneration namespace: biological_process def: "Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fibre, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:ef, GOC:mtg_muscle, PMID:16607119] xref: GO:0014815 is_a: CCO:P0001090 ! positive regulation of satellite cell activation involved in skeletal muscle regeneration [Term] id: CCO:P0001092 name: satellite cell asymmetric division namespace: biological_process def: "The asymmetric division of a satellite cell that occurs when a satellite cell divides to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool. Satellite cells are quiescent adult muscle stem cells that become activated to divide and differentiate in response to muscle damage." [GOC:ef, GOC:mtg_muscle, PMID:16607119] xref: GO:0014833 is_a: CCO:P0000821 ! asymmetric cell division [Term] id: CCO:P0001093 name: satellite cell maintenance involved in skeletal muscle regeneration namespace: biological_process def: "The process essential to mantain a ready source of satellite cells. It consists of the return of activated satellite cells to a quiescent state after proliferation to replenish the satellite cell pool. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fibre, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:dph, GOC:ef, GOC:mtg_muscle, GOC:tb, PMID:16607119] synonym: "satellite cell compartment self-renewal involved in skeletal muscle regeneration" EXACT [GOC:dph, GOC:tb] synonym: "satellite cell population maintenance" EXACT [] synonym: "satellite cell self-renewal" BROAD [] xref: GO:0014834 is_a: CCO:P0001981 ! somatic stem cell maintenance relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN [Term] id: CCO:P0001094 name: satellite cell proliferation namespace: biological_process def: "The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fibre, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage." [GOC:ef, GOC:mtg_muscle, PMID:16607119] xref: GO:0014841 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001095 name: regulation of satellite cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of satellite cell proliferation." [GOC:ef, GOC:mtg_muscle, PMID:16607119] xref: GO:0014842 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0001094 ! satellite cell proliferation [Term] id: CCO:P0001096 name: growth factor dependent regulation of satellite cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta." [GOC:ef, GOC:mtg_muscle, PMID:16607119] xref: GO:0014843 is_a: CCO:P0001095 ! regulation of satellite cell proliferation [Term] id: CCO:P0001097 name: myoblast cell proliferation involved in skeletal muscle regeneration namespace: biological_process def: "The multiplication or reproduction of myoblast cells, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle, PMID:16607119] xref: GO:0014844 is_a: CCO:P0003091 ! myoblast proliferation [Term] id: CCO:P0001098 name: striated muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:ef, GOC:mtg_muscle] xref: GO:0014855 is_a: CCO:P0001749 ! muscle cell proliferation [Term] id: CCO:P0001099 name: skeletal muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." [CL:0000188, GOC:ef, GOC:mtg_muscle] xref: GO:0014856 is_a: CCO:P0001098 ! striated muscle cell proliferation [Term] id: CCO:P0001100 name: regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] xref: GO:0014857 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0001099 ! skeletal muscle cell proliferation [Term] id: CCO:P0001101 name: positive regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] xref: GO:0014858 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0001100 ! regulation of skeletal muscle cell proliferation relationship: positively_regulates CCO:P0001099 ! skeletal muscle cell proliferation [Term] id: CCO:P0001102 name: negative regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] xref: GO:0014859 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0001100 ! regulation of skeletal muscle cell proliferation relationship: negatively_regulates CCO:P0001099 ! skeletal muscle cell proliferation [Term] id: CCO:P0001103 name: cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction namespace: biological_process def: "A process whereby cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction." [GOC:mtg_muscle] xref: GO:0014868 is_a: CCO:P0001106 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction [Term] id: CCO:P0001104 name: cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction namespace: biological_process def: "The process whereby actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction." [GOC:mtg_muscle] xref: GO:0014871 is_a: CCO:P0001106 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction [Term] id: CCO:P0001105 name: myoblast cell division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle] xref: GO:0014872 is_a: CCO:P0003077 ! cell division [Term] id: CCO:P0001106 name: regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction." [GOC:dph, GOC:mtg_muscle, GOC:tb] xref: GO:0014880 is_a: CCO:P0001745 ! regulation of muscle filament sliding [Term] id: CCO:P0001107 name: regulation of smooth muscle cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] xref: GO:0014910 is_a: CCO:P0001257 ! regulation of cell migration relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0055006 ! ACE_HUMAN [Term] id: CCO:P0001108 name: positive regulation of smooth muscle cell migration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] xref: GO:0014911 is_a: CCO:P0001107 ! regulation of smooth muscle cell migration is_a: CCO:P0001258 ! positive regulation of cell migration relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN [Term] id: CCO:P0001109 name: negative regulation of smooth muscle cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] xref: GO:0014912 is_a: CCO:P0001107 ! regulation of smooth muscle cell migration is_a: CCO:P0001259 ! negative regulation of cell migration relationship: has_participant CCO:B0006002 ! TRIB1_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN relationship: has_participant CCO:B0055174 ! IBP5_HUMAN [Term] id: CCO:P0001110 name: regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction namespace: biological_process def: "Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction." [GOC:dph, GOC:mtg_muscle, GOC:tb] xref: GO:0014915 is_a: CCO:P0001106 ! regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction is_a: CCO:P0001746 ! regulation of muscle filament sliding speed [Term] id: CCO:P0001111 name: Wnt receptor signaling pathway namespace: biological_process def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state." [GOC:dph, GOC:go_curators, PMID:11532397] synonym: "frizzled signaling pathway" EXACT [] synonym: "frizzled signalling pathway" EXACT [] synonym: "Wnt receptor signalling pathway" EXACT [] xref: GO:0007222 xref: GO:0016055 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0001407 ! HBP1_HUMAN relationship: has_participant CCO:B0001537 ! CSK22_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0002146 ! TF7L1_HUMAN relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005211 ! DVL2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005400 ! BRD7_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005428 ! CSK21_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005633 ! FBW1A_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN relationship: has_participant CCO:B0005690 ! TLE3_HUMAN relationship: has_participant CCO:B0005839 ! CTND1_HUMAN relationship: has_participant CCO:B0005897 ! CSK2B_HUMAN relationship: has_participant CCO:B0005941 ! FBW1B_HUMAN relationship: has_participant CCO:B0005987 ! AES_HUMAN relationship: has_participant CCO:B0006047 ! WNT16_HUMAN relationship: has_participant CCO:B0006061 ! BCL9_HUMAN relationship: has_participant CCO:B0006062 ! PYGO2_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0016924 ! TLE4_HUMAN relationship: has_participant CCO:B0017481 ! KC1D_HUMAN relationship: has_participant CCO:B0017844 ! TGFI1_HUMAN relationship: has_participant CCO:B0020414 ! KC1G3_HUMAN relationship: has_participant CCO:B0020417 ! KC1G1_HUMAN relationship: has_participant CCO:B0020420 ! KC1G2_HUMAN relationship: has_participant CCO:B0021692 ! WISP1_HUMAN relationship: has_participant CCO:B0025071 ! NHERF_HUMAN relationship: has_participant CCO:B0025951 ! LRP5_HUMAN relationship: has_participant CCO:B0025967 ! LRP6_HUMAN relationship: has_participant CCO:B0031540 ! APC2_HUMAN relationship: has_participant CCO:B0031667 ! RSPO2_HUMAN relationship: has_participant CCO:B0031669 ! RSPO1_HUMAN relationship: has_participant CCO:B0031672 ! RSPO4_HUMAN relationship: has_participant CCO:B0031673 ! RSPO3_HUMAN relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0032521 ! LRRF2_HUMAN relationship: has_participant CCO:B0036139 ! SENP2_HUMAN relationship: has_participant CCO:B0038579 ! CBPZ_HUMAN relationship: has_participant CCO:B0038854 ! FZD5_HUMAN relationship: has_participant CCO:B0038855 ! FZD1_HUMAN relationship: has_participant CCO:B0038856 ! FZD7_HUMAN relationship: has_participant CCO:B0038857 ! FZD2_HUMAN relationship: has_participant CCO:B0038861 ! FZD9_HUMAN relationship: has_participant CCO:B0038863 ! FZD8_HUMAN relationship: has_participant CCO:B0038865 ! FZD10_HUMAN relationship: has_participant CCO:B0039905 ! TLE6_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: has_participant CCO:B0053803 ! A6NE61_HUMAN relationship: has_participant CCO:B0053953 ! A8K0G1_HUMAN relationship: has_participant CCO:B0054223 ! B1AJZ6_HUMAN relationship: has_participant CCO:B0054340 ! WN10B_HUMAN relationship: has_participant CCO:B0054341 ! WNT7A_HUMAN relationship: has_participant CCO:B0054363 ! DVL1_HUMAN relationship: has_participant CCO:B0054388 ! WNT9A_HUMAN relationship: has_participant CCO:B0054389 ! WNT9B_HUMAN relationship: has_participant CCO:B0054390 ! TX1B3_HUMAN relationship: has_participant CCO:B0054549 ! FZD6_HUMAN relationship: has_participant CCO:B0054641 ! FRAT2_HUMAN relationship: has_participant CCO:B0054709 ! DKK1_HUMAN relationship: has_participant CCO:B0054822 ! WNT11_HUMAN relationship: has_participant CCO:B0054891 ! WNT1_HUMAN relationship: has_participant CCO:B0054945 ! WNT2_HUMAN relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: has_participant CCO:B0055306 ! TCF7_HUMAN relationship: has_participant CCO:B0055336 ! WNT5A_HUMAN relationship: has_participant CCO:B0055410 ! KC1A_HUMAN relationship: has_participant CCO:B0055516 ! DVL1L_HUMAN relationship: has_participant CCO:B0055548 ! WNT3_HUMAN relationship: has_participant CCO:B0055549 ! WNT3A_HUMAN relationship: has_participant CCO:B0055550 ! WNT4_HUMAN relationship: has_participant CCO:B0055551 ! WNT7B_HUMAN relationship: has_participant CCO:B0055562 ! FBXW4_HUMAN relationship: has_participant CCO:B0055681 ! NDP_HUMAN relationship: has_participant CCO:B0056077 ! DIXC1_HUMAN relationship: has_participant CCO:B0056271 ! Q3SY79_HUMAN relationship: has_participant CCO:B0056327 ! Q4VAJ4_HUMAN relationship: has_participant CCO:B0056358 ! KLH12_HUMAN relationship: has_participant CCO:B0056399 ! Q59G81_HUMAN relationship: has_participant CCO:B0056513 ! Q5JYX2_HUMAN relationship: has_participant CCO:B0056575 ! SFRP5_HUMAN relationship: has_participant CCO:B0056613 ! Q5TEH8_HUMAN relationship: has_participant CCO:B0056725 ! NXN_HUMAN relationship: has_participant CCO:B0056733 ! SFRP4_HUMAN relationship: has_participant CCO:B0056849 ! Q6N0A5_HUMAN relationship: has_participant CCO:B0056970 ! SOSD1_HUMAN relationship: has_participant CCO:B0057051 ! Q6ZS96_HUMAN relationship: has_participant CCO:B0057057 ! Q6ZSP0_HUMAN relationship: has_participant CCO:B0057236 ! KAISO_HUMAN relationship: has_participant CCO:B0057442 ! Q8N2D3_HUMAN relationship: has_participant CCO:B0057464 ! SFRP1_HUMAN relationship: has_participant CCO:B0057498 ! KC1AL_HUMAN relationship: has_participant CCO:B0057574 ! KREM2_HUMAN relationship: has_participant CCO:B0057937 ! Q8TDT9_HUMAN relationship: has_participant CCO:B0058090 ! SFRP3_HUMAN relationship: has_participant CCO:B0058101 ! FRAT1_HUMAN relationship: has_participant CCO:B0058118 ! DVL3_HUMAN relationship: has_participant CCO:B0058124 ! WNT2B_HUMAN relationship: has_participant CCO:B0058125 ! WNT8B_HUMAN relationship: has_participant CCO:B0058128 ! NKD2_HUMAN relationship: has_participant CCO:B0058130 ! NKD1_HUMAN relationship: has_participant CCO:B0058221 ! SFRP2_HUMAN relationship: has_participant CCO:B0058294 ! KREM1_HUMAN relationship: has_participant CCO:B0058636 ! WN10A_HUMAN relationship: has_participant CCO:B0058665 ! WNT8A_HUMAN relationship: has_participant CCO:B0058666 ! WNT5B_HUMAN relationship: has_participant CCO:B0058674 ! PORCN_HUMAN relationship: has_participant CCO:B0058686 ! CXXC4_HUMAN relationship: has_participant CCO:B0058851 ! FZD3_HUMAN relationship: has_participant CCO:B0058960 ! DACT1_HUMAN relationship: has_participant CCO:B0059047 ! CACO1_HUMAN relationship: has_participant CCO:B0059050 ! DAPLE_HUMAN relationship: has_participant CCO:B0059080 ! DKK3_HUMAN relationship: has_participant CCO:B0059084 ! DKK4_HUMAN relationship: has_participant CCO:B0059085 ! DKK2_HUMAN relationship: has_participant CCO:B0059175 ! LEF1_HUMAN relationship: has_participant CCO:B0059233 ! FZD4_HUMAN relationship: has_participant CCO:B0059298 ! INVS_HUMAN relationship: has_participant CCO:B0059315 ! AXN2_HUMAN relationship: has_participant CCO:B0059345 ! PYGO1_HUMAN relationship: has_participant CCO:B0059389 ! WIF1_HUMAN relationship: has_participant CCO:B0059405 ! WNT6_HUMAN [Term] id: CCO:P0001112 name: rhodopsin mediated signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon." [GOC:dph, GOC:hb, GOC:tb] synonym: "rhodopsin mediated signalling pathway" EXACT [GOC:dph, GOC:tb] xref: GO:0016056 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0054919 ! OPSD_HUMAN relationship: has_participant CCO:B0054974 ! ARRS_HUMAN relationship: has_participant CCO:B0056115 ! RK_HUMAN [Term] id: CCO:P0001113 name: regulation of membrane potential in photoreceptor cell namespace: biological_process def: "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] synonym: "changes in polarization state of photoreceptor cell membrane" EXACT [GOC:dph, GOC:tb] xref: GO:0016057 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0054724 ! O95098_HUMAN relationship: part_of CCO:P0001112 ! rhodopsin mediated signaling pathway [Term] id: CCO:P0001114 name: maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling namespace: biological_process def: "Maintenance of the excited state of a photoreceptor cell to produce a steady state current as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] synonym: "maintenance of rhodopsin mediated signaling" RELATED [] synonym: "maintenance of rhodopsin mediated signalling" EXACT [] xref: GO:0016058 is_a: CCO:P0001113 ! regulation of membrane potential in photoreceptor cell relationship: has_participant CCO:B0054724 ! O95098_HUMAN [Term] id: CCO:P0001115 name: deactivation of rhodopsin mediated signaling namespace: biological_process def: "The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon)." [PMID:8316831] synonym: "deactivation of rhodopsin mediated signalling" EXACT [] xref: GO:0016059 is_a: CCO:P0001235 ! regulation of rhodopsin mediated signaling [Term] id: CCO:P0001116 name: metarhodopsin inactivation namespace: biological_process def: "Process by which metarhodopsin is prevented from generating molecular signals." [GOC:hb] xref: GO:0016060 is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: part_of CCO:P0001115 ! deactivation of rhodopsin mediated signaling [Term] id: CCO:P0001117 name: adaptation of rhodopsin mediated signaling namespace: biological_process def: "Process by which the visual system can modulate its sensitivity and response to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation." [PMID:1962207] synonym: "adaptation of rhodopsin mediated signalling" EXACT [] xref: GO:0016062 is_a: CCO:P0001236 ! adaptation of signaling pathway [Term] id: CCO:P0001118 name: positive regulation of macroautophagy namespace: biological_process def: "Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation." [GOC:go_curators, PMID:9412464] synonym: "activation of macroautophagy" NARROW [] synonym: "stimulation of macroautophagy" NARROW [] synonym: "up regulation of macroautophagy" EXACT [] synonym: "up-regulation of macroautophagy" EXACT [] synonym: "upregulation of macroautophagy" EXACT [] xref: GO:0016239 is_a: CCO:P0000955 ! positive regulation of autophagy is_a: CCO:P0001119 ! regulation of macroautophagy [Term] id: CCO:P0001119 name: regulation of macroautophagy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of macroautophagy." [GOC:krc] xref: GO:0016241 is_a: CCO:P0000953 ! regulation of autophagy [Term] id: CCO:P0001120 name: negative regulation of macroautophagy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of macroautophagy." [GOC:go_curators] synonym: "down regulation of macroautophagy" EXACT [] synonym: "down-regulation of macroautophagy" EXACT [] synonym: "downregulation of macroautophagy" EXACT [] synonym: "inhibition of macroautophagy" NARROW [] xref: GO:0016242 is_a: CCO:P0000954 ! negative regulation of autophagy is_a: CCO:P0001119 ! regulation of macroautophagy [Term] id: CCO:P0001121 name: hyperphosphorylation of RNA polymerase II namespace: biological_process def: "The production of an RNA polymerase II enzyme where the C-Terminal Domain (CTD) of the largest subunit is extensively phosphorylated, as a result of activation of kinases, deactivation of phosphatases, or both. This phosphorylation occurs during the initiation phase and is required for the transition to the elongation phase. Specific types of phosphorylation within the CTD are associated with recruitment of complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex." [GOC:krc, PMID:15964991] synonym: "CTD domain phosphorylation of RNA polymerase II" NARROW [] xref: GO:0016245 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:P0001122 name: RNA interference namespace: biological_process def: "The process by which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and occurs through a specific decrease in the level of mRNA of both host genes and transgenes." [GOC:ems, PMID:11201747, PMID:11713190] synonym: "RNAi" EXACT [] xref: GO:0016246 is_a: CCO:P0002002 ! posttranscriptional gene silencing by RNA relationship: has_participant CCO:B0006265 ! CELF1_HUMAN relationship: has_participant CCO:B0057111 ! SND1_HUMAN [Term] id: CCO:P0001123 name: posttranscriptional gene silencing namespace: biological_process def: "The inactivation of gene expression by a posttranscriptional mechanism." [GOC:mah, PMID:15020054] synonym: "cosuppression" RELATED [] synonym: "PTGS" EXACT [] synonym: "quelling" EXACT [] xref: GO:0016441 is_a: CCO:P0001008 ! posttranscriptional regulation of gene expression is_a: CCO:P0001125 ! gene silencing is_a: CCO:P0002023 ! regulation of gene expression, epigenetic [Term] id: CCO:P0001124 name: dosage compensation complex assembly during dosage compensation by hyperactivation of X chromosome namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome." [GOC:jl] synonym: "dosage compensation complex assembly (sensu Insecta)" EXACT [] xref: GO:0016457 is_a: CCO:P0002122 ! dosage compensation complex assembly relationship: part_of CCO:P0000845 ! dosage compensation, by hyperactivation of X chromosome [Term] id: CCO:P0001125 name: gene silencing namespace: biological_process def: "Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation." [GOC:jic] comment: Note that this process is the opposite of long-term maintenance of gene activation. subset: goslim_pir synonym: "long-term maintenance of gene inactivation" RELATED [] xref: GO:0016458 is_a: CCO:P0001019 ! negative regulation of gene expression relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002148 ! CHM1A_HUMAN relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN [Term] id: CCO:P0001126 name: regulation of embryonic cell shape namespace: biological_process def: "Any process that modulates the surface configuration of an embryonic cell." [GOC:dph, GOC:tb] synonym: "shape changes of embryonic cells" RELATED [GOC:dph, GOC:tb] xref: GO:0016476 is_a: CCO:P0000822 ! regulation of cell shape [Term] id: CCO:P0001127 name: negative regulation of transcription from RNA polymerase I promoter namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter." [GOC:go_curators] synonym: "down regulation of transcription from RNA polymerase I promoter" EXACT [] synonym: "down-regulation of transcription from RNA polymerase I promoter" EXACT [] synonym: "downregulation of transcription from RNA polymerase I promoter" EXACT [] synonym: "inhibition of transcription from RNA polymerase I promoter" NARROW [] synonym: "negative regulation of transcription from Pol I promoter" EXACT [] xref: GO:0016479 is_a: CCO:P0000656 ! regulation of transcription from RNA polymerase I promoter is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:P0001128 name: negative regulation of transcription from RNA polymerase III promoter namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter." [GOC:go_curators] synonym: "down regulation of transcription from RNA polymerase III promoter" EXACT [] synonym: "down-regulation of transcription from RNA polymerase III promoter" EXACT [] synonym: "downregulation of transcription from RNA polymerase III promoter" EXACT [] synonym: "inhibition of transcription from RNA polymerase III promoter" NARROW [] synonym: "negative regulation of transcription from Pol III promoter" EXACT [] xref: GO:0016480 is_a: CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: has_participant CCO:B0005301 ! MAF1_HUMAN [Term] id: CCO:P0001129 name: negative regulation of transcription namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of transcription" EXACT [] synonym: "down-regulation of transcription" EXACT [] synonym: "downregulation of transcription" EXACT [] synonym: "inhibition of transcription" NARROW [] xref: GO:0016481 is_a: CCO:P0001019 ! negative regulation of gene expression is_a: CCO:P0002369 ! regulation of transcription is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001722 ! KHDR1_HUMAN relationship: has_participant CCO:B0001836 ! PDCD4_HUMAN relationship: has_participant CCO:B0001928 ! ERN2_HUMAN relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002111 ! PCGF6_HUMAN relationship: has_participant CCO:B0002160 ! GRLF1_HUMAN relationship: has_participant CCO:B0002235 ! TIM_HUMAN relationship: has_participant CCO:B0005317 ! CBX5_HUMAN relationship: has_participant CCO:B0005365 ! DMAP1_HUMAN relationship: has_participant CCO:B0005402 ! PIAS4_HUMAN relationship: has_participant CCO:B0005425 ! ATX1_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN relationship: has_participant CCO:B0005510 ! MBD1_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005694 ! SDS3_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN relationship: has_participant CCO:B0006038 ! NKRF_HUMAN relationship: has_participant CCO:B0006069 ! PO2F1_HUMAN relationship: has_participant CCO:B0006085 ! ZNF24_HUMAN relationship: has_participant CCO:B0015399 ! MAD4_HUMAN relationship: has_participant CCO:B0016937 ! BTAF1_HUMAN relationship: has_participant CCO:B0017927 ! MYST3_HUMAN relationship: has_participant CCO:B0017931 ! MYST4_HUMAN relationship: has_participant CCO:B0020930 ! GLIS2_HUMAN relationship: has_participant CCO:B0026163 ! LANC2_HUMAN relationship: has_participant CCO:B0026583 ! SNX6_HUMAN relationship: has_participant CCO:B0028073 ! RFX3_HUMAN relationship: has_participant CCO:B0032520 ! LRRF1_HUMAN relationship: has_participant CCO:B0033622 ! RUNX2_HUMAN relationship: has_participant CCO:B0034068 ! FABP4_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0037050 ! TRI33_HUMAN relationship: has_participant CCO:B0038855 ! FZD1_HUMAN relationship: has_participant CCO:B0043604 ! DEDD_HUMAN relationship: has_participant CCO:B0043605 ! DEDD2_HUMAN relationship: has_participant CCO:B0048571 ! SNW1_HUMAN relationship: has_participant CCO:B0049576 ! NRG1_HUMAN relationship: has_participant CCO:B0054326 ! O00485_HUMAN relationship: has_participant CCO:B0054327 ! O00486_HUMAN relationship: has_participant CCO:B0054445 ! PER1_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN relationship: has_participant CCO:B0054485 ! AT8B1_HUMAN relationship: has_participant CCO:B0054546 ! ZEB2_HUMAN relationship: has_participant CCO:B0054634 ! LRCH4_HUMAN relationship: has_participant CCO:B0054639 ! NR1I2_HUMAN relationship: has_participant CCO:B0054749 ! SIX3_HUMAN relationship: has_participant CCO:B0054845 ! CALC_HUMAN relationship: has_participant CCO:B0054992 ! VDR_HUMAN relationship: has_participant CCO:B0055156 ! MYF6_HUMAN relationship: has_participant CCO:B0055345 ! ELK3_HUMAN relationship: has_participant CCO:B0055404 ! GSH1_HUMAN relationship: has_participant CCO:B0055483 ! NR0B1_HUMAN relationship: has_participant CCO:B0055525 ! NR1H2_HUMAN relationship: has_participant CCO:B0055884 ! CBX3_HUMAN relationship: has_participant CCO:B0055920 ! NAB1_HUMAN relationship: has_participant CCO:B0056013 ! CBX2_HUMAN relationship: has_participant CCO:B0056102 ! NAB2_HUMAN relationship: has_participant CCO:B0056205 ! ZN423_HUMAN relationship: has_participant CCO:B0056331 ! BCL7A_HUMAN relationship: has_participant CCO:B0056620 ! Q5TG39_HUMAN relationship: has_participant CCO:B0056621 ! Q5TG40_HUMAN relationship: has_participant CCO:B0057268 ! COMD7_HUMAN relationship: has_participant CCO:B0057376 ! NELFD_HUMAN relationship: has_participant CCO:B0057384 ! YAF2_HUMAN relationship: has_participant CCO:B0057490 ! EID2_HUMAN relationship: has_participant CCO:B0057552 ! SMYD1_HUMAN relationship: has_participant CCO:B0057609 ! DMBX1_HUMAN relationship: has_participant CCO:B0058011 ! NELFB_HUMAN relationship: has_participant CCO:B0058154 ! PBIP1_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN relationship: has_participant CCO:B0058227 ! Q96I83_HUMAN relationship: has_participant CCO:B0058380 ! FER3L_HUMAN relationship: has_participant CCO:B0058381 ! UIMC1_HUMAN relationship: has_participant CCO:B0058432 ! PHB2_HUMAN relationship: has_participant CCO:B0058481 ! MBB1A_HUMAN relationship: has_participant CCO:B0058529 ! MAD3_HUMAN relationship: has_participant CCO:B0058641 ! ZN350_HUMAN relationship: has_participant CCO:B0058653 ! WWP1_HUMAN relationship: has_participant CCO:B0058748 ! MYST1_HUMAN relationship: has_participant CCO:B0058768 ! SMUF2_HUMAN relationship: has_participant CCO:B0058878 ! PRDM6_HUMAN relationship: has_participant CCO:B0058934 ! RNF12_HUMAN relationship: has_participant CCO:B0058962 ! BCLF1_HUMAN relationship: has_participant CCO:B0058999 ! UBIP1_HUMAN relationship: has_participant CCO:B0059065 ! MBD2_HUMAN [Term] id: CCO:P0001130 name: protein import into peroxisome matrix, receptor recycling namespace: biological_process def: "The process by which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol." [PMID:11687502] synonym: "peroxisome matrix protein import, receptor recycling" EXACT [] synonym: "peroxisome receptor recycling" RELATED [] synonym: "protein transport into peroxisome matrix, receptor recycling" EXACT [] synonym: "PTS receptor recycling" RELATED [] synonym: "receptor recycling during peroxisome matrix protein import" EXACT [] synonym: "receptor recycling during protein import into peroxisome matrix" EXACT [] synonym: "receptor recycling during protein transport into peroxisome matrix" EXACT [] xref: GO:0016562 is_a: CCO:P0000486 ! receptor recycling [Term] id: CCO:P0001131 name: Rac protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state." [GOC:bf] synonym: "Rac mediated signal transduction" EXACT [] xref: GO:0016601 is_a: CCO:P0000782 ! Ras protein signal transduction relationship: has_participant CCO:B0005669 ! ELMO1_HUMAN relationship: has_participant CCO:B0054705 ! FARP2_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0059026 ! PTAD1_HUMAN relationship: has_participant CCO:B0059177 ! DBNL_HUMAN [Term] id: CCO:P0001132 name: regulation of transforming growth factor beta receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of activity of any TGFbeta receptor signaling pathway." [GOC:mah] synonym: "regulation of TGF-beta receptor signaling pathway" EXACT [] synonym: "regulation of TGFbeta receptor signaling pathway" EXACT [] synonym: "regulation of transforming growth factor beta receptor signalling pathway" EXACT [] xref: GO:0017015 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0055092 ! EGLN_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056159 ! NP311_HUMAN relationship: has_participant CCO:B0057449 ! LTBP4_HUMAN relationship: has_participant CCO:B0057490 ! EID2_HUMAN relationship: has_participant CCO:B0058768 ! SMUF2_HUMAN relationship: regulates CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0001133 name: negative regulation of transcriptional preinitiation complex assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcriptional preinitiation complex assembly." [GOC:go_curators] synonym: "down regulation of transcriptional preinitiation complex assembly" EXACT [] synonym: "down-regulation of transcriptional preinitiation complex assembly" EXACT [] synonym: "downregulation of transcriptional preinitiation complex assembly" EXACT [] synonym: "inhibition of transcriptional preinitiation complex assembly" NARROW [] synonym: "negative regulation of transcriptional pre-initiation complex assembly" EXACT [] synonym: "negative regulation of transcriptional pre-initiation complex biosynthesis" EXACT [] synonym: "negative regulation of transcriptional preinitiation complex formation" EXACT [] xref: GO:0017055 is_a: CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter is_a: CCO:P0002599 ! regulation of transcriptional preinitiation complex assembly is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0005929 ! HMGB1_HUMAN relationship: has_participant CCO:B0050276 ! HMGLX_HUMAN relationship: negatively_regulates CCO:P0003028 ! transcriptional preinitiation complex assembly [Term] id: CCO:P0001134 name: stem cell division namespace: biological_process def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jic, ISBN:0582227089] synonym: "stem cell renewal" EXACT [] xref: GO:0017145 is_a: CCO:P0003077 ! cell division [Term] id: CCO:P0001135 name: negative regulation of translation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA." [GOC:isa_complete] subset: gosubset_prok synonym: "down regulation of protein biosynthetic process" EXACT [] synonym: "down-regulation of protein biosynthetic process" EXACT [] synonym: "downregulation of protein biosynthetic process" EXACT [] synonym: "inhibition of protein biosynthetic process" NARROW [] synonym: "negative regulation of protein anabolism" EXACT [] synonym: "negative regulation of protein biosynthesis" EXACT [] synonym: "negative regulation of protein biosynthetic process" EXACT [] synonym: "negative regulation of protein formation" EXACT [] synonym: "negative regulation of protein synthesis" EXACT [] synonym: "protein biosynthesis inhibitor activity" RELATED [] synonym: "protein biosynthetic process inhibitor activity" RELATED [] xref: GO:0016478 xref: GO:0017148 is_a: CCO:P0000660 ! regulation of translation is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0005674 ! E2AK1_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN relationship: has_participant CCO:B0054319 ! IF2B3_HUMAN relationship: has_participant CCO:B0054565 ! 4EBP3_HUMAN relationship: has_participant CCO:B0055320 ! IF4A3_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN relationship: has_participant CCO:B0055928 ! 4EBP2_HUMAN relationship: has_participant CCO:B0059000 ! IF2B1_HUMAN relationship: has_participant CCO:B0059028 ! NDUAD_HUMAN relationship: has_participant CCO:B0059325 ! PRG3_HUMAN relationship: has_participant CCO:B0059410 ! IF2B2_HUMAN [Term] id: CCO:P0001136 name: suppression by virus of host apoptosis namespace: biological_process def: "Any viral process that results in the inhibition of apoptosis, facilitating prolonged cell survival during viral replication." [ISBN:0781718325] synonym: "negative regulation by virus of host apoptosis" EXACT [] synonym: "negative regulation of apoptosis by virus" EXACT [] synonym: "suppression of apoptosis in host by virus" EXACT [] xref: GO:0019050 is_a: CCO:P0003184 ! negative regulation by symbiont of host programmed cell death [Term] id: CCO:P0001137 name: induction by virus of host apoptosis namespace: biological_process def: "The set of viral processes that result in the induction of apoptosis of infected cells, facilitating release and spread of progeny virions." [ISBN:0781718325] synonym: "activation by virus of host apoptosis" EXACT [] synonym: "activation by virus of host apoptotic programmed cell death" EXACT [] synonym: "activation of apoptosis in host by virus" EXACT [] synonym: "induction by virus of host apoptotic programmed cell death" EXACT [] synonym: "induction of apoptosis in host by virus" EXACT [] xref: GO:0019051 is_a: CCO:P0003182 ! induction by symbiont of host apoptosis [Term] id: CCO:P0001138 name: modulation by virus of host transcription namespace: biological_process def: "The modulation by viral gene products of host RNA polymerase II facilitated transcription." [ISBN:0781718325] synonym: "modification by virus of host transcription" EXACT [] synonym: "viral perturbation of host cell transcription" EXACT [] xref: GO:0019056 is_a: CCO:P0003181 ! modulation by symbiont of host transcription [Term] id: CCO:P0001139 name: regulation of host mRNA translation by virus namespace: biological_process def: "Any process by which a virus modulates the frequency, rate or extent of translation of host mRNA." [ISBN:0781718325] synonym: "host cell protein synthesis shutoff" BROAD [] synonym: "host cell shutoff" BROAD [] synonym: "modification by virus of host cell mRNA translation" EXACT [] synonym: "regulation of host translation by virus" EXACT [] synonym: "regulation of translation in host by virus" EXACT [] synonym: "viral host shutoff protein" RELATED [] synonym: "viral perturbation of host cell mRNA translation" EXACT [] xref: GO:0019057 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0001140 name: regulation of fatty acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of fatty acid metabolism" EXACT [] xref: GO:0006632 xref: GO:0019217 is_a: CCO:P0001404 ! regulation of cellular metabolic process relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0055786 ! PPARA_HUMAN [Term] id: CCO:P0001141 name: regulation of steroid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of steroid metabolism" EXACT [] xref: GO:0019218 is_a: CCO:P0001404 ! regulation of cellular metabolic process relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN [Term] id: CCO:P0001142 name: regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] xref: GO:0019219 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001143 name: regulation of phosphate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of phosphate metabolism" EXACT [] xref: GO:0019220 is_a: CCO:P0003053 ! regulation of phosphorus metabolic process [Term] id: CCO:P0001144 name: cytokine and chemokine mediated signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of a cytokine or chemokine binding to a cell surface receptor." [GOC:mah] synonym: "cytokine and chemokine mediated signalling pathway" EXACT [] xref: GO:0019221 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005325 ! IL1R1_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0015956 ! IFNK_HUMAN relationship: has_participant CCO:B0023418 ! STAT4_HUMAN relationship: has_participant CCO:B0025042 ! IL3RB_HUMAN relationship: has_participant CCO:B0033477 ! LRP8_HUMAN relationship: has_participant CCO:B0041664 ! PLF4_HUMAN relationship: has_participant CCO:B0042813 ! IL2RB_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0054343 ! SH2B2_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0054952 ! CSF3_HUMAN relationship: has_participant CCO:B0054977 ! KIT_HUMAN relationship: has_participant CCO:B0055256 ! CCR1_HUMAN relationship: has_participant CCO:B0055344 ! CCR2_HUMAN relationship: has_participant CCO:B0055355 ! LIFR_HUMAN relationship: has_participant CCO:B0055431 ! CEBPA_HUMAN relationship: has_participant CCO:B0055645 ! X3CL1_HUMAN relationship: has_participant CCO:B0055740 ! PLP2_HUMAN relationship: has_participant CCO:B0056413 ! Q59GU9_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058896 ! DUOX2_HUMAN relationship: has_participant CCO:B0058897 ! DUOX1_HUMAN relationship: has_participant CCO:B0059069 ! CLCF1_HUMAN relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:P0001145 name: calcium-mediated signaling namespace: biological_process def: "A series of molecular signals in which a cell uses calcium ions to convert an extracellular signal into a response." [GOC:ceb] synonym: "calcium signaling" EXACT [] synonym: "calcium signalling" EXACT [] synonym: "calcium-mediated signalling" EXACT [] xref: GO:0019722 is_a: CCO:P0001148 ! second-messenger-mediated signaling relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001504 ! IL8_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0016489 ! PA24B_HUMAN relationship: has_participant CCO:B0026418 ! NUDT4_HUMAN relationship: has_participant CCO:B0029424 ! BTK_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0053766 ! A4GU14_HUMAN relationship: has_participant CCO:B0053767 ! A4LA69_HUMAN relationship: has_participant CCO:B0054492 ! LAT_HUMAN relationship: has_participant CCO:B0055223 ! AGTR1_HUMAN relationship: has_participant CCO:B0055318 ! V1AR_HUMAN relationship: has_participant CCO:B0055335 ! CASR_HUMAN relationship: has_participant CCO:B0055512 ! RCAN1_HUMAN relationship: has_participant CCO:B0055971 ! RCAN2_HUMAN relationship: has_participant CCO:B0056425 ! Q5ECL3_HUMAN relationship: has_participant CCO:B0056726 ! MCTP2_HUMAN relationship: has_participant CCO:B0056727 ! MCTP1_HUMAN relationship: has_participant CCO:B0056982 ! Q6ZMM3_HUMAN relationship: has_participant CCO:B0057126 ! BHLH8_HUMAN relationship: has_participant CCO:B0057171 ! Q7Z555_HUMAN relationship: has_participant CCO:B0057305 ! Q86YJ0_HUMAN relationship: has_participant CCO:B0058383 ! KKCC2_HUMAN relationship: has_participant CCO:B0058632 ! NMUR2_HUMAN relationship: has_participant CCO:B0058644 ! NTAL_HUMAN relationship: has_participant CCO:B0058780 ! NMUR1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: has_participant CCO:B0059190 ! RCAN3_HUMAN relationship: has_participant CCO:B0059393 ! GPR44_HUMAN [Term] id: CCO:P0001146 name: regulation of isoprenoid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of isoprenoid metabolism" EXACT [] xref: GO:0019747 is_a: CCO:P0001404 ! regulation of cellular metabolic process relationship: has_participant CCO:B0055613 ! NPC2_HUMAN [Term] id: CCO:P0001147 name: stem cell maintenance namespace: biological_process def: "The process by which an organism retains a population of stem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate." [GOC:mah, ISBN:0878932437] xref: GO:0019827 is_a: CCO:P0002410 ! negative regulation of cell differentiation relationship: has_participant CCO:B0001500 ! FGF4_HUMAN relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0042120 ! NODAL_HUMAN [Term] id: CCO:P0001148 name: second-messenger-mediated signaling namespace: biological_process def: "A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell." [GOC:mah, ISBN:0815316194] subset: gosubset_prok synonym: "second messenger mediated signaling" EXACT [] synonym: "second messenger mediated signalling" EXACT [] synonym: "second messenger-mediated signaling" EXACT [] synonym: "second messenger-mediated signalling" EXACT [] synonym: "second-messenger-mediated signalling" EXACT [] xref: GO:0019932 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0056176 ! DGKD_HUMAN [Term] id: CCO:P0001149 name: cAMP-mediated signaling namespace: biological_process def: "A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response." [GOC:mah] synonym: "3',5' cAMP-mediated signaling" EXACT [] synonym: "3',5' cAMP-mediated signalling" EXACT [] synonym: "3',5'-cAMP-mediated signaling" EXACT [] synonym: "3',5'-cAMP-mediated signalling" EXACT [] synonym: "adenosine 3',5'-cyclophosphate-mediated signaling" EXACT [] synonym: "adenosine 3',5'-cyclophosphate-mediated signalling" EXACT [] synonym: "cAMP signaling" EXACT [] synonym: "cAMP signalling" EXACT [] synonym: "cAMP-mediated signalling" EXACT [] synonym: "cyclic AMP-mediated signaling" EXACT [] synonym: "cyclic AMP-mediated signalling" EXACT [] xref: GO:0019933 is_a: CCO:P0001151 ! cyclic-nucleotide-mediated signaling relationship: has_participant CCO:B0015123 ! GLP1R_HUMAN relationship: has_participant CCO:B0054454 ! NDUS4_HUMAN relationship: has_participant CCO:B0055928 ! 4EBP2_HUMAN relationship: has_participant CCO:B0059362 ! RPGF2_HUMAN [Term] id: CCO:P0001150 name: cGMP-mediated signaling namespace: biological_process def: "A series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response." [GOC:mah] synonym: "cGMP-mediated signalling" EXACT [] xref: GO:0019934 is_a: CCO:P0001151 ! cyclic-nucleotide-mediated signaling relationship: has_participant CCO:B0025070 ! PDZD3_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN [Term] id: CCO:P0001151 name: cyclic-nucleotide-mediated signaling namespace: biological_process def: "A series of molecular signals in which a cell uses a cyclic nucleotide to convert an extracellular signal into a response." [GOC:ceb] subset: gosubset_prok synonym: "cyclic-nucleotide-mediated signalling" EXACT [] xref: GO:0019935 is_a: CCO:P0001148 ! second-messenger-mediated signaling relationship: has_participant CCO:B0026418 ! NUDT4_HUMAN [Term] id: CCO:P0001152 name: negative regulation of anti-apoptosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of anti-apoptosis." [GOC:go_curators] synonym: "down regulation of anti-apoptosis" EXACT [] synonym: "down-regulation of anti-apoptosis" EXACT [] synonym: "downregulation of anti-apoptosis" EXACT [] synonym: "inhibition of anti-apoptosis" NARROW [] xref: GO:0019987 is_a: CCO:P0002544 ! regulation of anti-apoptosis relationship: has_participant CCO:B0026602 ! P85B_HUMAN relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0054753 ! TFIP8_HUMAN relationship: negatively_regulates CCO:P0000671 ! anti-apoptosis [Term] id: CCO:P0001153 name: schizogony namespace: biological_process def: "Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously." [GOC:mb] xref: GO:0020014 is_a: CCO:P0003077 ! cell division [Term] id: CCO:P0001154 name: cell proliferation in hindbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0021534 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001155 name: retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification namespace: biological_process def: "The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. synonym: "retinoic acid receptor signalling pathway involved in ventral spinal cord interneuron specification" EXACT [] xref: GO:0021774 is_a: CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:P0001156 name: smoothened signaling pathway involved in ventral spinal cord interneuron specification namespace: biological_process def: "The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. synonym: "smoothened signalling pathway involved in ventral spinal cord interneuron specification" EXACT [] xref: GO:0021775 is_a: CCO:P0001190 ! smoothened signaling pathway in ventral spinal cord patterning relationship: has_participant CCO:B0005850 ! GLI3_HUMAN relationship: has_participant CCO:B0054965 ! GLI2_HUMAN [Term] id: CCO:P0001157 name: smoothened signaling pathway involved in spinal cord motor neuron cell fate specification namespace: biological_process def: "The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15936325] comment: This term was added by GO_REF:0000021. synonym: "smoothened signalling pathway involved in spinal cord motor neuron cell fate specification" EXACT [] xref: GO:0021776 is_a: CCO:P0001190 ! smoothened signaling pathway in ventral spinal cord patterning relationship: has_participant CCO:B0005850 ! GLI3_HUMAN [Term] id: CCO:P0001158 name: BMP signaling pathway involved in spinal cord association neuron specification namespace: biological_process def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to its commitment to an association neuron fate." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12593981] comment: This term was added by GO_REF:0000021. synonym: "BMP signalling pathway involved in spinal cord association neuron specification" EXACT [] synonym: "bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification" EXACT [] synonym: "bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification" EXACT [] xref: GO:0021777 is_a: CCO:P0001195 ! BMP signaling pathway in spinal cord dorsal-ventral patterning [Term] id: CCO:P0001159 name: negative regulation of cell adhesion in the ventricular zone namespace: biological_process def: "The process that results in the loss of attachments of a cell in the ventricular zone." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. synonym: "down regulation of cell adhesion in the ventricular zone" EXACT [] synonym: "down-regulation of cell adhesion in the ventricular zone" EXACT [] synonym: "downregulation of cell adhesion in the ventricular zone" EXACT [] synonym: "inhibition of cell adhesion in the ventricular zone" NARROW [] xref: GO:0021804 is_a: CCO:P0000707 ! negative regulation of cell adhesion [Term] id: CCO:P0001160 name: cytosolic calcium signaling involved in the initiation of cell movement in glial-mediated radial cell migration namespace: biological_process def: "The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. synonym: "cytosolic calcium signalling involved in the initiation of cell movement in glial-mediated radial cell migration" EXACT [] xref: GO:0021808 is_a: CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:P0001161 name: negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination namespace: biological_process def: "The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. synonym: "down regulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT [] synonym: "down-regulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT [] synonym: "downregulation of cell-glial cell adhesion involved in cerebral cortex lamination" EXACT [] synonym: "inhibition of cell-glial cell adhesion involved in cerebral cortex lamination" NARROW [] xref: GO:0021821 is_a: CCO:P0001238 ! negative regulation of cell-cell adhesion [Term] id: CCO:P0001162 name: negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration namespace: biological_process def: "The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. synonym: "down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" EXACT [] synonym: "down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" EXACT [] synonym: "downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" EXACT [] synonym: "inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration" NARROW [] synonym: "negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration" EXACT [GOC:dph] xref: GO:0021822 is_a: CCO:P0001259 ! negative regulation of cell migration [Term] id: CCO:P0001163 name: directional guidance of interneurons involved in migration from the subpallium to the cortex namespace: biological_process def: "The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. xref: GO:0021840 is_a: CCO:P0001257 ! regulation of cell migration [Term] id: CCO:P0001164 name: chemoattraction involved in interneuron migration from the subpallium to the cortex namespace: biological_process def: "The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. xref: GO:0021841 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001163 ! directional guidance of interneurons involved in migration from the subpallium to the cortex [Term] id: CCO:P0001165 name: chemorepulsion involved in interneuron migration from the subpallium to the cortex namespace: biological_process def: "The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. xref: GO:0021842 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001163 ! directional guidance of interneurons involved in migration from the subpallium to the cortex [Term] id: CCO:P0001166 name: neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration namespace: biological_process def: "The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. xref: GO:0021845 is_a: CCO:P0001257 ! regulation of cell migration [Term] id: CCO:P0001167 name: cell proliferation in forebrain namespace: biological_process def: "The creation of greater cell numbers in the forebrain due to cell division of progenitor cells." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0021846 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001168 name: neuroblast division in the ventricular zone namespace: biological_process def: "The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. xref: GO:0021847 is_a: CCO:P0001178 ! forebrain ventricular zone progenitor cell division [Term] id: CCO:P0001169 name: neuroblast division in the subpallium namespace: biological_process def: "The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. synonym: "neuroblast division in the ventral telencephalon" EXACT [PMID:16226447] xref: GO:0021848 is_a: CCO:P0003220 ! neuroblast division relationship: part_of CCO:P0001219 ! subpallium cell proliferation in the forebrain [Term] id: CCO:P0001170 name: neuroblast division in the subventricular zone namespace: biological_process def: "The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. xref: GO:0021849 is_a: CCO:P0001179 ! forebrain neuroblast division relationship: part_of CCO:P0001167 ! cell proliferation in forebrain [Term] id: CCO:P0001171 name: glioblast cell division in the subpallium namespace: biological_process def: "The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. synonym: "glioblast cell division in the ventral telencephalon" EXACT [PMID:16226447] xref: GO:0021850 is_a: CCO:P0002904 ! glioblast cell division relationship: part_of CCO:P0001219 ! subpallium cell proliferation in the forebrain [Term] id: CCO:P0001172 name: neuroblast division in the dorsal lateral ganglionic eminence namespace: biological_process def: "The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12626695] comment: This term was added by GO_REF:0000021. xref: GO:0021851 is_a: CCO:P0001169 ! neuroblast division in the subpallium [Term] id: CCO:P0001173 name: radial glial cell division in the forebrain namespace: biological_process def: "The mitotic division of radial glial cells in the developing forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021864 is_a: CCO:P0003077 ! cell division relationship: part_of CCO:P0001167 ! cell proliferation in forebrain [Term] id: CCO:P0001174 name: symmetric radial glial cell division in the forebrain namespace: biological_process def: "The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021865 is_a: CCO:P0001173 ! radial glial cell division in the forebrain [Term] id: CCO:P0001175 name: asymmetric radial glial cell division in the forebrain namespace: biological_process def: "The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021866 is_a: CCO:P0001173 ! radial glial cell division in the forebrain [Term] id: CCO:P0001176 name: neuron-producing asymmetric radial glial cell division in the forebrain namespace: biological_process def: "The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021867 is_a: CCO:P0001175 ! asymmetric radial glial cell division in the forebrain [Term] id: CCO:P0001177 name: ventricular zone cell-producing asymmetric radial glial cell division in the forebrain namespace: biological_process def: "The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021868 is_a: CCO:P0001175 ! asymmetric radial glial cell division in the forebrain [Term] id: CCO:P0001178 name: forebrain ventricular zone progenitor cell division namespace: biological_process def: "The mitotic division of a basal progenitor giving rise to two neurons." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021869 is_a: CCO:P0003077 ! cell division relationship: part_of CCO:P0001167 ! cell proliferation in forebrain [Term] id: CCO:P0001179 name: forebrain neuroblast division namespace: biological_process def: "The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast. As in, but not restricted to, the vertebrates (Vertebrata, ncbi_taxonomy_id:7742)." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0021873 is_a: CCO:P0003220 ! neuroblast division [Term] id: CCO:P0001180 name: Wnt receptor signaling pathway in forebrain neuroblast division namespace: biological_process def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. synonym: "Wnt receptor signalling pathway in forebrain neuroblast division" EXACT [] xref: GO:0021874 is_a: CCO:P0001111 ! Wnt receptor signaling pathway relationship: part_of CCO:P0001179 ! forebrain neuroblast division [Term] id: CCO:P0001181 name: fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division namespace: biological_process def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. synonym: "fibroblast growth factor receptor signalling pathway in forebrain neuroblast division" EXACT [] xref: GO:0021875 is_a: CCO:P0000823 ! fibroblast growth factor receptor signaling pathway relationship: part_of CCO:P0001179 ! forebrain neuroblast division [Term] id: CCO:P0001182 name: Notch signaling pathway in forebrain neuroblast division namespace: biological_process def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. synonym: "Notch signalling pathway in forebrain neuroblast division" EXACT [] xref: GO:0021876 is_a: CCO:P0000754 ! Notch signaling pathway relationship: part_of CCO:P0001179 ! forebrain neuroblast division [Term] id: CCO:P0001183 name: Notch signaling pathway involved in forebrain neuron fate commitment namespace: biological_process def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. synonym: "Notch signalling pathway involved in forebrain neuron fate commitment" EXACT [] xref: GO:0021880 is_a: CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:P0001184 name: Wnt receptor signaling pathway involved in forebrain neuron fate commitment namespace: biological_process def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. synonym: "Wnt receptor signalling pathway involved in forebrain neuron fate commitment" EXACT [] xref: GO:0021881 is_a: CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:P0001185 name: regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. xref: GO:0021882 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001186 name: fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment namespace: biological_process def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447] comment: This term was added by GO_REF:0000021. synonym: "fibroblast growth factor receptor signalling pathway involved in forebrain neuron fate commitment" EXACT [] xref: GO:0021899 is_a: CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:P0001187 name: fibroblast growth factor receptor signaling pathway involved in spinal cord anterior-posterior patterning namespace: biological_process def: "The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. synonym: "fibroblast growth factor receptor signalling pathway in spinal cord anterior-posterior patterning" EXACT [] xref: GO:0021907 is_a: CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:P0001188 name: retinoic acid receptor signaling pathway in spinal cord anterior-posterior patterning namespace: biological_process def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. synonym: "retinoic acid receptor signalling pathway in spinal cord anterior-posterior patterning" EXACT [] xref: GO:0021908 is_a: CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:P0001189 name: regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. xref: GO:0021909 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001190 name: smoothened signaling pathway in ventral spinal cord patterning namespace: biological_process def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. synonym: "smoothened signalling pathway in ventral spinal cord patterning" EXACT [] xref: GO:0021910 is_a: CCO:P0000758 ! smoothened signaling pathway [Term] id: CCO:P0001191 name: regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. xref: GO:0021912 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001192 name: regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. xref: GO:0021913 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001193 name: negative regulation of smoothened signaling pathway in ventral spinal cord patterning namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. synonym: "down regulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT [] synonym: "down-regulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT [] synonym: "downregulation of smoothened signaling pathway in ventral spinal cord patterning" EXACT [] synonym: "inhibition of smoothened signaling pathway in ventral spinal cord patterning" NARROW [] synonym: "negative regulation of smoothened signalling pathway in ventral spinal cord patterning" EXACT [] xref: GO:0021914 is_a: CCO:P0002586 ! negative regulation of smoothened signaling pathway relationship: negatively_regulates CCO:P0001190 ! smoothened signaling pathway in ventral spinal cord patterning [Term] id: CCO:P0001194 name: regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:11262869] comment: This term was added by GO_REF:0000021. xref: GO:0021918 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001195 name: BMP signaling pathway in spinal cord dorsal-ventral patterning namespace: biological_process def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12593981] comment: This term was added by GO_REF:0000021. synonym: "BMP signalling pathway in spinal cord dorsal-ventral patterning" EXACT [] synonym: "bone morphogenetic protein signaling pathway in spinal cord dorsal-ventral patterning" EXACT [] synonym: "bone morphogenetic protein signalling pathway in spinal cord dorsal-ventral patterning" EXACT [] xref: GO:0021919 is_a: CCO:P0001270 ! BMP signaling pathway relationship: part_of CCO:P0001193 ! negative regulation of smoothened signaling pathway in ventral spinal cord patterning [Term] id: CCO:P0001196 name: regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12593981] comment: This term was added by GO_REF:0000021. xref: GO:0021920 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001197 name: regulation of cell proliferation in dorsal spinal cord namespace: biological_process def: "The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0021921 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0000943 ! cell proliferation in dorsal spinal cord [Term] id: CCO:P0001198 name: Wnt receptor signaling pathway involved in regulation of cell proliferation in dorsal spinal cord namespace: biological_process def: "The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12593981] comment: This term was added by GO_REF:0000021. synonym: "Wnt receptor signalling pathway involved in regulation of cell proliferation in dorsal spinal cord" EXACT [] xref: GO:0021922 is_a: CCO:P0001111 ! Wnt receptor signaling pathway relationship: part_of CCO:P0001197 ! regulation of cell proliferation in dorsal spinal cord [Term] id: CCO:P0001199 name: cell proliferation in the hindbrain ventricular zone namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:12593981, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021923 is_a: CCO:P0001154 ! cell proliferation in hindbrain [Term] id: CCO:P0001200 name: cell proliferation in the external granule layer namespace: biological_process def: "The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021924 is_a: CCO:P0001154 ! cell proliferation in hindbrain [Term] id: CCO:P0001201 name: Purkinje cell precursor proliferation namespace: biological_process def: "The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021925 is_a: CCO:P0001199 ! cell proliferation in the hindbrain ventricular zone [Term] id: CCO:P0001202 name: Golgi cell precursor proliferation namespace: biological_process def: "The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021926 is_a: CCO:P0001199 ! cell proliferation in the hindbrain ventricular zone [Term] id: CCO:P0001203 name: deep nuclear neuron precursor proliferation namespace: biological_process def: "The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021927 is_a: CCO:P0001199 ! cell proliferation in the hindbrain ventricular zone [Term] id: CCO:P0001204 name: basket cell precursor proliferation namespace: biological_process def: "The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021928 is_a: CCO:P0001199 ! cell proliferation in the hindbrain ventricular zone [Term] id: CCO:P0001205 name: stellate cell precursor proliferation namespace: biological_process def: "The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021929 is_a: CCO:P0001199 ! cell proliferation in the hindbrain ventricular zone [Term] id: CCO:P0001206 name: granule cell precursor proliferation namespace: biological_process def: "The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021930 is_a: CCO:P0001200 ! cell proliferation in the external granule layer [Term] id: CCO:P0001207 name: rostral hindbrain neuronal precursor cell proliferation namespace: biological_process def: "The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021931 is_a: CCO:P0001200 ! cell proliferation in the external granule layer [Term] id: CCO:P0001208 name: regulation of granule cell precursor proliferation namespace: biological_process def: "The process that modulates the frequency, rate or extent of granule cell precursor proliferation." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. xref: GO:0021936 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0001206 ! granule cell precursor proliferation [Term] id: CCO:P0001209 name: Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation namespace: biological_process def: "The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. synonym: "Purkinje cell-granule cell precursor cell signalling involved in regulation of granule cell precursor cell proliferation" EXACT [] xref: GO:0021937 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001212 ! positive regulation of granule cell precursor proliferation [Term] id: CCO:P0001210 name: smoothened signaling pathway in regulation of granule cell precursor cell proliferation namespace: biological_process def: "The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in granule cells that contributes to the regulation of proliferation of the cells." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. synonym: "smoothened signalling pathway in regulation of granule cell precursor cell proliferation" EXACT [] xref: GO:0021938 is_a: CCO:P0000758 ! smoothened signaling pathway relationship: has_participant CCO:B0006039 ! SMO_HUMAN relationship: has_participant CCO:B0054922 ! GLI1_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: part_of CCO:P0001209 ! Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation [Term] id: CCO:P0001211 name: extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation namespace: biological_process def: "The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. synonym: "extracellular matrix-granule cell signalling involved in regulation of granule cell precursor proliferation" EXACT [] xref: GO:0021939 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001213 ! negative regulation of granule cell precursor proliferation [Term] id: CCO:P0001212 name: positive regulation of granule cell precursor proliferation namespace: biological_process def: "The process that activates or increases the rate or extent of granule cell precursor proliferation." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. synonym: "activation of granule cell precursor proliferation" NARROW [] synonym: "stimulation of granule cell precursor proliferation" NARROW [] synonym: "up regulation of granule cell precursor proliferation" EXACT [] synonym: "up-regulation of granule cell precursor proliferation" EXACT [] synonym: "upregulation of granule cell precursor proliferation" EXACT [] xref: GO:0021940 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0001208 ! regulation of granule cell precursor proliferation relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: positively_regulates CCO:P0001206 ! granule cell precursor proliferation [Term] id: CCO:P0001213 name: negative regulation of granule cell precursor proliferation namespace: biological_process def: "The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15157725] comment: This term was added by GO_REF:0000021. synonym: "down regulation of granule cell precursor proliferation" EXACT [] synonym: "down-regulation of granule cell precursor proliferation" EXACT [] synonym: "downregulation of granule cell precursor proliferation" EXACT [] synonym: "inhibition of granule cell precursor proliferation" NARROW [] xref: GO:0021941 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0001208 ! regulation of granule cell precursor proliferation relationship: negatively_regulates CCO:P0001206 ! granule cell precursor proliferation [Term] id: CCO:P0001214 name: positive regulation of granule cell migration by calcium namespace: biological_process def: "The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, GOC:tb, PMID:15157725] comment: This term was added by GO_REF:0000021. synonym: "calcium-mediated activation of granule cell migration" NARROW [] synonym: "calcium-mediated positive regulation of granule cell migration" EXACT [GOC:dph, GOC:tb] synonym: "calcium-mediated stimulation of granule cell migration" NARROW [] synonym: "calcium-mediated up regulation of granule cell migration" EXACT [] synonym: "calcium-mediated up-regulation of granule cell migration" EXACT [] synonym: "calcium-mediated upregulation of granule cell migration" EXACT [] xref: GO:0021945 is_a: CCO:P0001145 ! calcium-mediated signaling is_a: CCO:P0001258 ! positive regulation of cell migration [Term] id: CCO:P0001215 name: cell proliferation involved in neural plate elongation namespace: biological_process def: "The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:15806586] comment: This term was added by GO_REF:0000021. xref: GO:0021992 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001216 name: negative regulation of anterior neural cell fate commitment of the neural plate namespace: biological_process def: "Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, GOC:tb] comment: This term was added by GO_REF:0000021. synonym: "caudalization of neural plate" EXACT [] synonym: "down regulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "down-regulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "downregulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "inhibition of anterior neural cell fate of the neural plate" NARROW [] synonym: "negative regulation of anterior neural cell fate of the neural plate" EXACT [GOC:dph, GOC:tb] synonym: "posteriorization" BROAD [] xref: GO:0022001 is_a: CCO:P0000941 ! negative regulation of cell fate commitment [Term] id: CCO:P0001217 name: Wnt receptor signaling pathway involved in negative regulation of anterior neural cell fate commitment of the neural plate namespace: biological_process def: "The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, GOC:tb] comment: This term was added by GO_REF:0000021. synonym: "Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate" NARROW [] synonym: "Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [GOC:dph, GOC:tb] synonym: "Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [] xref: GO:0022002 is_a: CCO:P0001111 ! Wnt receptor signaling pathway is_a: CCO:P0001216 ! negative regulation of anterior neural cell fate commitment of the neural plate [Term] id: CCO:P0001218 name: fibroblast growth factor receptor signaling pathway involved in negative regulation of anterior neural cell fate commitment of the neural plate namespace: biological_process def: "The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, GOC:tb] comment: This term was added by GO_REF:0000021. synonym: "fgf receptor signaling involved in down regulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "fgf receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "fgf receptor signaling involved in downregulation of anterior neural cell fate of the neural plate" EXACT [] synonym: "fgf receptor signaling involved in inhibition of anterior neural cell fate of the neural plate" NARROW [] synonym: "fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [GOC:dph, GOC:tb] synonym: "fgf receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate" EXACT [] xref: GO:0022003 is_a: CCO:P0000823 ! fibroblast growth factor receptor signaling pathway is_a: CCO:P0001216 ! negative regulation of anterior neural cell fate commitment of the neural plate [Term] id: CCO:P0001219 name: subpallium cell proliferation in the forebrain namespace: biological_process def: "The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022012 is_a: CCO:P0001167 ! cell proliferation in forebrain [Term] id: CCO:P0001220 name: pallium cell proliferation in the forebrain namespace: biological_process def: "The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022013 is_a: CCO:P0001167 ! cell proliferation in forebrain [Term] id: CCO:P0001221 name: radial glial cell division in the subpallium namespace: biological_process def: "The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022014 is_a: CCO:P0001173 ! radial glial cell division in the forebrain relationship: part_of CCO:P0001219 ! subpallium cell proliferation in the forebrain [Term] id: CCO:P0001222 name: radial glial cell division in the pallium namespace: biological_process def: "The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022015 is_a: CCO:P0003077 ! cell division relationship: part_of CCO:P0001220 ! pallium cell proliferation in the forebrain [Term] id: CCO:P0001223 name: glioblast cell division in the pallium namespace: biological_process def: "The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022016 is_a: CCO:P0002904 ! glioblast cell division relationship: part_of CCO:P0001220 ! pallium cell proliferation in the forebrain [Term] id: CCO:P0001224 name: neuroblast division in the pallium namespace: biological_process def: "The division of neuroblast in the pallium. Neuroblasts are precursor cells that give rise to neurons." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022017 is_a: CCO:P0001134 ! stem cell division relationship: part_of CCO:P0001220 ! pallium cell proliferation in the forebrain [Term] id: CCO:P0001225 name: lateral ganglionic eminence cell proliferation namespace: biological_process def: "The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022018 is_a: CCO:P0001219 ! subpallium cell proliferation in the forebrain [Term] id: CCO:P0001226 name: dorsal lateral ganglionic eminence cell proliferation namespace: biological_process def: "The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022019 is_a: CCO:P0001219 ! subpallium cell proliferation in the forebrain relationship: part_of CCO:P0001225 ! lateral ganglionic eminence cell proliferation [Term] id: CCO:P0001227 name: medial ganglionic eminence cell proliferation namespace: biological_process def: "The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022020 is_a: CCO:P0001219 ! subpallium cell proliferation in the forebrain [Term] id: CCO:P0001228 name: caudal ganglionic eminence cell proliferation namespace: biological_process def: "The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022021 is_a: CCO:P0001219 ! subpallium cell proliferation in the forebrain [Term] id: CCO:P0001229 name: septal cell proliferation namespace: biological_process def: "The multiplication or reproduction of septal cells, resulting in the expansion of a cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. synonym: "septum cell proliferation" EXACT [] xref: GO:0022022 is_a: CCO:P0001219 ! subpallium cell proliferation in the forebrain [Term] id: CCO:P0001230 name: BMP signaling pathway involved in forebrain neuron fate commitment namespace: biological_process def: "The series of molecular signals generated as a consequence of a bone morphogenic protein receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. synonym: "BMP signalling pathway involved in forebrain neuron fate commitment" EXACT [] synonym: "bone morphogenetic protein signaling pathway involved in forebrain neuron fate commitment" EXACT [] synonym: "bone morphogenetic protein signalling pathway involved in forebrain neuron fate commitment" EXACT [] xref: GO:0022024 is_a: CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:P0001231 name: leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment namespace: biological_process def: "The series of molecular signals generated as a consequence of a leukemia inhibitory factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. synonym: "leukemia inhibitory factor signalling pathway involved in forebrain neuron fate commitment" EXACT [] xref: GO:0022025 is_a: CCO:P0002905 ! leukemia inhibitory factor signaling pathway [Term] id: CCO:P0001232 name: epidermal growth factor signaling pathway involved in forebrain neuron fate commitment namespace: biological_process def: "The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. synonym: "epidermal growth factor signalling pathway involved in forebrain neuron fate commitment" EXACT [] xref: GO:0022026 is_a: CCO:P0000715 ! epidermal growth factor receptor signaling pathway [Term] id: CCO:P0001233 name: interkinetic nuclear migration namespace: biological_process def: "The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022027 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001167 ! cell proliferation in forebrain [Term] id: CCO:P0001234 name: rhombomere cell proliferation namespace: biological_process def: "The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population." [GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06] comment: This term was added by GO_REF:0000021. xref: GO:0022034 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001235 name: regulation of rhodopsin mediated signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling." [GOC:mah] synonym: "regulation of rhodopsin mediated signalling" EXACT [] xref: GO:0022400 is_a: CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: part_of CCO:P0001112 ! rhodopsin mediated signaling pathway [Term] id: CCO:P0001236 name: adaptation of signaling pathway namespace: biological_process def: "The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus." [GOC:isa_complete] synonym: "adaptation of signal transduction pathway" EXACT [] synonym: "adaptation of signalling pathway" EXACT [] synonym: "desensitization of signaling pathway" EXACT [] synonym: "desensitization of signalling pathway" EXACT [] xref: GO:0022401 is_a: CCO:P0000886 ! negative regulation of signal transduction [Term] id: CCO:P0001237 name: regulation of cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." [GOC:isa_complete] xref: GO:0022407 is_a: CCO:P0001245 ! regulation of cell adhesion relationship: has_participant CCO:B0032349 ! CELR2_HUMAN [Term] id: CCO:P0001238 name: negative regulation of cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "down regulation of cell-cell adhesion" EXACT [] synonym: "down-regulation of cell-cell adhesion" EXACT [] synonym: "downregulation of cell-cell adhesion" EXACT [] synonym: "inhibition of cell-cell adhesion" NARROW [] xref: GO:0022408 is_a: CCO:P0000707 ! negative regulation of cell adhesion is_a: CCO:P0001237 ! regulation of cell-cell adhesion relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0002116 ! NOG1_HUMAN relationship: has_participant CCO:B0057878 ! B4GN2_HUMAN [Term] id: CCO:P0001239 name: positive regulation of cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "activation of cell-cell adhesion" NARROW [] synonym: "stimulation of cell-cell adhesion" NARROW [] synonym: "up regulation of cell-cell adhesion" EXACT [] synonym: "up-regulation of cell-cell adhesion" EXACT [] synonym: "upregulation of cell-cell adhesion" EXACT [] xref: GO:0022409 is_a: CCO:P0001237 ! regulation of cell-cell adhesion is_a: CCO:P0002553 ! positive regulation of cell adhesion relationship: has_participant CCO:B0055793 ! CD47_HUMAN relationship: has_participant CCO:B0059045 ! SIRPG_HUMAN [Term] id: CCO:P0001240 name: reproductive process in single-celled organism namespace: biological_process def: "A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism." [GOC:isa_complete] subset: gosubset_prok xref: GO:0022413 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001636 ! reproduction of a single-celled organism [Term] id: CCO:P0001241 name: regulation of cell morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process by which the size or shape of a cell is generated and organized." [GOC:isa_complete] subset: gosubset_prok synonym: "negative regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] xref: GO:0022604 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0001242 name: regulation of flagellum biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a flagellum." [GOC:go_curators] synonym: "regulation of flagella biogenesis" EXACT [] xref: GO:0030092 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis [Term] id: CCO:P0001243 name: regulation of endocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endocytosis." [GOC:go_curators] xref: GO:0030100 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0001349 ! BIN1_HUMAN relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0023550 ! RAB5C_HUMAN relationship: has_participant CCO:B0023553 ! RAB5B_HUMAN relationship: has_participant CCO:B0055510 ! AP2S1_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0055558 ! SYJ2B_HUMAN relationship: has_participant CCO:B0056037 ! SNX17_HUMAN relationship: has_participant CCO:B0057155 ! ZFY16_HUMAN relationship: has_participant CCO:B0058016 ! STON2_HUMAN relationship: has_participant CCO:B0059412 ! STON1_HUMAN [Term] id: CCO:P0001244 name: regulation of Wnt receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of the Wnt receptor mediated signal transduction pathway." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of frizzled signaling pathway" EXACT [] synonym: "regulation of frizzled signalling pathway" EXACT [] synonym: "regulation of Wnt receptor signalling pathway" EXACT [] xref: GO:0008590 xref: GO:0030111 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0002146 ! TF7L1_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0006019 ! LPP3_HUMAN relationship: has_participant CCO:B0036139 ! SENP2_HUMAN relationship: has_participant CCO:B0059043 ! MDFIC_HUMAN relationship: has_participant CCO:B0059175 ! LEF1_HUMAN relationship: regulates CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:P0001245 name: regulation of cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." [GOC:mah] subset: gosubset_prok synonym: "cell adhesion receptor regulator activity" RELATED [] xref: GO:0030155 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001504 ! IL8_HUMAN relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0005450 ! ICAM1_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN relationship: has_participant CCO:B0028292 ! DLL1_HUMAN relationship: has_participant CCO:B0053811 ! A6NF00_HUMAN relationship: has_participant CCO:B0053833 ! A6NGS5_HUMAN relationship: has_participant CCO:B0054195 ! B0YJ32_HUMAN relationship: has_participant CCO:B0054196 ! B0YJ33_HUMAN relationship: has_participant CCO:B0054418 ! LAMA5_HUMAN relationship: has_participant CCO:B0054487 ! O43535_HUMAN relationship: has_participant CCO:B0054577 ! CYTIP_HUMAN relationship: has_participant CCO:B0055184 ! LAMA1_HUMAN relationship: has_participant CCO:B0055957 ! IL18_HUMAN relationship: has_participant CCO:B0056063 ! CYH1_HUMAN relationship: has_participant CCO:B0056126 ! Q16161_HUMAN relationship: has_participant CCO:B0056431 ! Q5H8W3_HUMAN relationship: has_participant CCO:B0056656 ! Q5VUM2_HUMAN relationship: has_participant CCO:B0056963 ! Q6VU67_HUMAN relationship: has_participant CCO:B0056964 ! Q6VU68_HUMAN relationship: has_participant CCO:B0056965 ! Q6VU69_HUMAN [Term] id: CCO:P0001246 name: regulation of proteolysis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." [GOC:mah] subset: gosubset_prok synonym: "regulation of peptidolysis" EXACT [] xref: GO:0030162 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process relationship: has_participant CCO:B0054788 ! O95740_HUMAN relationship: has_participant CCO:B0054908 ! GDN_HUMAN relationship: has_participant CCO:B0055408 ! SPB4_HUMAN relationship: has_participant CCO:B0055723 ! UPAR_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0057449 ! LTBP4_HUMAN relationship: has_participant CCO:B0059165 ! SPB13_HUMAN [Term] id: CCO:P0001247 name: regulation of DNA replication initiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of initiation of DNA replication; the process by which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase." [GOC:mah] subset: gosubset_prok synonym: "DNA replication licencing" EXACT [] synonym: "DNA replication licensing" EXACT [] xref: GO:0030174 is_a: CCO:P0000639 ! regulation of DNA replication relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0002126 ! CDT1_HUMAN relationship: has_participant CCO:B0058386 ! WRIP1_HUMAN relationship: regulates CCO:P0000634 ! DNA replication initiation [Term] id: CCO:P0001248 name: positive regulation of Wnt receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Wnt receptor signaling pathway activity." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of frizzled signaling pathway" NARROW [] synonym: "activation of Wnt receptor signaling pathway" NARROW [] synonym: "positive regulation of frizzled signaling pathway" EXACT [] synonym: "positive regulation of frizzled signalling pathway" EXACT [] synonym: "positive regulation of Wnt receptor signalling pathway" EXACT [] synonym: "stimulation of frizzled signaling pathway" NARROW [] synonym: "stimulation of Wnt receptor signaling pathway" NARROW [] synonym: "up regulation of frizzled signaling pathway" EXACT [] synonym: "up regulation of Wnt receptor signaling pathway" EXACT [] synonym: "up-regulation of frizzled signaling pathway" EXACT [] synonym: "up-regulation of Wnt receptor signaling pathway" EXACT [] synonym: "upregulation of frizzled signaling pathway" EXACT [] synonym: "upregulation of Wnt receptor signaling pathway" EXACT [] xref: GO:0030177 xref: GO:0045811 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: positively_regulates CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:P0001249 name: negative regulation of Wnt receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of frizzled signaling pathway" EXACT [] synonym: "down regulation of Wnt receptor signaling pathway" EXACT [] synonym: "down-regulation of frizzled signaling pathway" EXACT [] synonym: "down-regulation of Wnt receptor signaling pathway" EXACT [] synonym: "downregulation of frizzled signaling pathway" EXACT [] synonym: "downregulation of Wnt receptor signaling pathway" EXACT [] synonym: "inhibition of frizzled signaling pathway" NARROW [] synonym: "inhibition of Wnt receptor signaling pathway" NARROW [] synonym: "negative regulation of frizzled signaling pathway" EXACT [] synonym: "negative regulation of frizzled signalling pathway" EXACT [] synonym: "negative regulation of Wnt receptor signalling pathway" EXACT [] xref: GO:0030178 xref: GO:0045810 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001244 ! regulation of Wnt receptor signaling pathway relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0005232 ! MDFI_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0006076 ! CNBP1_HUMAN relationship: has_participant CCO:B0054390 ! TX1B3_HUMAN relationship: has_participant CCO:B0054486 ! O43532_HUMAN relationship: has_participant CCO:B0054709 ! DKK1_HUMAN relationship: has_participant CCO:B0054749 ! SIX3_HUMAN relationship: has_participant CCO:B0057439 ! Q8N294_HUMAN relationship: has_participant CCO:B0058090 ! SFRP3_HUMAN relationship: has_participant CCO:B0058686 ! CXXC4_HUMAN relationship: has_participant CCO:B0058710 ! Q9H3R7_HUMAN relationship: has_participant CCO:B0058792 ! BARX1_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN relationship: has_participant CCO:B0059080 ! DKK3_HUMAN relationship: has_participant CCO:B0059084 ! DKK4_HUMAN relationship: has_participant CCO:B0059085 ! DKK2_HUMAN relationship: has_participant CCO:B0059339 ! CBY1_HUMAN relationship: negatively_regulates CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:P0001250 name: apoptotic nuclear changes namespace: biological_process def: "The morphological and physiological alterations undergone by the nucleus during apoptosis." [GOC:mah] xref: GO:0030262 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0021834 ! MOAP1_HUMAN relationship: has_participant CCO:B0043605 ! DEDD2_HUMAN relationship: has_participant CCO:B0059028 ! NDUAD_HUMAN relationship: part_of CCO:P0000839 ! apoptotic program [Term] id: CCO:P0001251 name: apoptotic chromosome condensation namespace: biological_process def: "The compaction of chromatin during apoptosis." [GOC:mah] synonym: "pyknosis" EXACT [] xref: GO:0030263 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0015270 ! DFFB_HUMAN relationship: has_participant CCO:B0059205 ! ACINU_HUMAN relationship: part_of CCO:P0001250 ! apoptotic nuclear changes [Term] id: CCO:P0001252 name: nuclear fragmentation during apoptosis namespace: biological_process def: "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." [GOC:mah, ISBN:0721639976] synonym: "apoptotic nuclear fragmentation" EXACT [] synonym: "nucleus fragmentation" EXACT [] xref: GO:0030264 is_a: CCO:P0000674 ! cell structure disassembly during apoptosis relationship: has_participant CCO:B0055351 ! CASP3_HUMAN relationship: part_of CCO:P0001250 ! apoptotic nuclear changes [Term] id: CCO:P0001253 name: rhodopsin mediated G-protein signaling, coupled to IP3 second messenger namespace: biological_process def: "The series of molecular signals generated as a consequence of light impinging on rhodopsin molecules in a photoreceptor cell, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate." [GOC:mah] synonym: "rhodopsin mediated G protein signaling, coupled to IP3 second messenger" EXACT [] synonym: "rhodopsin mediated G protein signalling, coupled to IP3 second messenger" EXACT [] synonym: "rhodopsin mediated G-protein signalling, coupled to IP3 second messenger" EXACT [] xref: GO:0030265 is_a: CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) relationship: part_of CCO:P0001112 ! rhodopsin mediated signaling pathway [Term] id: CCO:P0001254 name: positive regulation of cell growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell growth." [GOC:go_curators] subset: gosubset_prok synonym: "activation of cell growth" NARROW [] synonym: "stimulation of cell growth" NARROW [] synonym: "up regulation of cell growth" EXACT [] synonym: "up-regulation of cell growth" EXACT [] synonym: "upregulation of cell growth" EXACT [] xref: GO:0030307 is_a: CCO:P0000466 ! regulation of cell growth is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0055097 ! LOX12_HUMAN relationship: has_participant CCO:B0055883 ! Q13169_HUMAN relationship: has_participant CCO:B0057103 ! NOL8_HUMAN relationship: has_participant CCO:B0058631 ! DERL2_HUMAN [Term] id: CCO:P0001255 name: negative regulation of cell growth namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell growth." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of cell growth" EXACT [] synonym: "down-regulation of cell growth" EXACT [] synonym: "downregulation of cell growth" EXACT [] synonym: "inhibition of cell growth" NARROW [] xref: GO:0030308 xref: Reactome:110491 is_a: CCO:P0000466 ! regulation of cell growth is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0001998 ! Q8TEY4_HUMAN relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0002039 ! SIPA1_HUMAN relationship: has_participant CCO:B0002060 ! NEB2_HUMAN relationship: has_participant CCO:B0002082 ! CGRF1_HUMAN relationship: has_participant CCO:B0002128 ! TSYL2_HUMAN relationship: has_participant CCO:B0002217 ! ING1_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005779 ! ENOA_HUMAN relationship: has_participant CCO:B0016680 ! ANPRA_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0022312 ! Q3LRW3_HUMAN relationship: has_participant CCO:B0022431 ! OSGI1_HUMAN relationship: has_participant CCO:B0025035 ! Q7Z324_HUMAN relationship: has_participant CCO:B0031622 ! CDD_HUMAN relationship: has_participant CCO:B0036934 ! HNF4A_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0043829 ! PSRC1_HUMAN relationship: has_participant CCO:B0049794 ! PPT1_HUMAN relationship: has_participant CCO:B0054315 ! O00366_HUMAN relationship: has_participant CCO:B0054644 ! NDUS3_HUMAN relationship: has_participant CCO:B0054873 ! FETUA_HUMAN relationship: has_participant CCO:B0054982 ! MLRV_HUMAN relationship: has_participant CCO:B0055059 ! ANFB_HUMAN relationship: has_participant CCO:B0055145 ! ENPP1_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055443 ! GBG4_HUMAN relationship: has_participant CCO:B0055615 ! BTG1_HUMAN relationship: has_participant CCO:B0055961 ! SRTD2_HUMAN relationship: has_participant CCO:B0056759 ! JADE1_HUMAN relationship: has_participant CCO:B0056819 ! CAPR2_HUMAN relationship: has_participant CCO:B0058084 ! ESR2_HUMAN relationship: has_participant CCO:B0058147 ! RERG_HUMAN relationship: has_participant CCO:B0058328 ! DCBD2_HUMAN relationship: has_participant CCO:B0058356 ! SG3A1_HUMAN relationship: has_participant CCO:B0058577 ! PCD24_HUMAN relationship: has_participant CCO:B0058798 ! WFDC1_HUMAN relationship: has_participant CCO:B0059028 ! NDUAD_HUMAN relationship: has_participant CCO:B0059128 ! NDRG3_HUMAN relationship: has_participant CCO:B0059140 ! IP6K2_HUMAN relationship: has_participant CCO:B0059180 ! SRTD3_HUMAN relationship: has_participant CCO:B0059181 ! GDF2_HUMAN relationship: has_participant CCO:B0059299 ! T53G5_HUMAN [Term] id: CCO:P0001256 name: DNA damage response, signal transduction by p53 class mediator namespace: biological_process def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:go_curators] synonym: "DNA damage response, activation of p53" RELATED [] synonym: "p53-mediated DNA damage response" BROAD [] xref: GO:0006976 xref: GO:0030330 is_a: CCO:P0002125 ! DNA damage response, signal transduction relationship: has_participant CCO:B0001398 ! TRIA1_HUMAN relationship: has_participant CCO:B0001421 ! NBN_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN [Term] id: CCO:P0001257 name: regulation of cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators] xref: GO:0030334 is_a: CCO:P0003071 ! regulation of cell motility relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0002245 ! JAG2_HUMAN relationship: has_participant CCO:B0005635 ! GNA13_HUMAN relationship: has_participant CCO:B0006093 ! LAMA4_HUMAN relationship: has_participant CCO:B0028290 ! JAG1_HUMAN relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0033141 ! ITB3_HUMAN relationship: has_participant CCO:B0038093 ! ABI3_HUMAN relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0053811 ! A6NF00_HUMAN relationship: has_participant CCO:B0053833 ! A6NGS5_HUMAN relationship: has_participant CCO:B0054195 ! B0YJ32_HUMAN relationship: has_participant CCO:B0054196 ! B0YJ33_HUMAN relationship: has_participant CCO:B0054418 ! LAMA5_HUMAN relationship: has_participant CCO:B0054733 ! UNC5C_HUMAN relationship: has_participant CCO:B0054777 ! NET1_HUMAN relationship: has_participant CCO:B0054908 ! GDN_HUMAN relationship: has_participant CCO:B0055184 ! LAMA1_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN relationship: has_participant CCO:B0055607 ! SMS_HUMAN relationship: has_participant CCO:B0055833 ! NEXN_HUMAN relationship: has_participant CCO:B0055914 ! GAB1_HUMAN relationship: has_participant CCO:B0056431 ! Q5H8W3_HUMAN relationship: has_participant CCO:B0056656 ! Q5VUM2_HUMAN relationship: has_participant CCO:B0056963 ! Q6VU67_HUMAN relationship: has_participant CCO:B0056964 ! Q6VU68_HUMAN relationship: has_participant CCO:B0056965 ! Q6VU69_HUMAN relationship: has_participant CCO:B0058051 ! ROBO4_HUMAN [Term] id: CCO:P0001258 name: positive regulation of cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators] subset: gosubset_prok synonym: "activation of cell migration" NARROW [] synonym: "stimulation of cell migration" NARROW [] synonym: "up regulation of cell migration" EXACT [] synonym: "up-regulation of cell migration" EXACT [] synonym: "upregulation of cell migration" EXACT [] xref: GO:0030335 is_a: CCO:P0001257 ! regulation of cell migration is_a: CCO:P0003073 ! positive regulation of cell motility relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005967 ! LAMB1_HUMAN relationship: has_participant CCO:B0005985 ! TRIP6_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN relationship: has_participant CCO:B0018011 ! RRAS2_HUMAN relationship: has_participant CCO:B0020505 ! PGFRA_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0059377 ! ANGL3_HUMAN [Term] id: CCO:P0001259 name: negative regulation of cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "down regulation of cell migration" EXACT [] synonym: "down-regulation of cell migration" EXACT [] synonym: "downregulation of cell migration" EXACT [] synonym: "inhibition of cell migration" NARROW [] xref: GO:0030336 is_a: CCO:P0001257 ! regulation of cell migration is_a: CCO:P0003072 ! negative regulation of cell motility relationship: has_participant CCO:B0001371 ! LX15B_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0002116 ! NOG1_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0018007 ! RRAS_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0024597 ! CEND3_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: has_participant CCO:B0043439 ! VINC_HUMAN relationship: has_participant CCO:B0054889 ! THY1_HUMAN relationship: has_participant CCO:B0054935 ! ABHD2_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056401 ! Q59GA0_HUMAN relationship: has_participant CCO:B0056463 ! MIA3_HUMAN relationship: has_participant CCO:B0058129 ! KISSR_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: has_participant CCO:B0059402 ! CLIC4_HUMAN [Term] id: CCO:P0001260 name: RNA interference, production of siRNA namespace: biological_process def: "Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides." [PMID:11524674] synonym: "RNA interference, production of guide RNAs" EXACT [] xref: GO:0030422 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001122 ! RNA interference [Term] id: CCO:P0001261 name: RNA interference, targeting of mRNA for destruction namespace: biological_process def: "The process by which small interfering RNAs target cognate mRNA molecules for degradation." [PMID:11524674] xref: GO:0030423 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001122 ! RNA interference [Term] id: CCO:P0001262 name: ascospore formation namespace: biological_process def: "The process by which a diploid cell undergoes meiosis, and the meiotic products acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota)." [GOC:mah, PMID:16339736] synonym: "ascospore biosynthesis" EXACT [] synonym: "spore formation (sensu Fungi)" BROAD [] synonym: "sporulation (sensu Fungi)" BROAD [] synonym: "sporulation (sensu Saccharomyces)" EXACT [] xref: GO:0007151 xref: GO:0030437 is_a: CCO:P0001240 ! reproductive process in single-celled organism [Term] id: CCO:P0001263 name: regulation of complement activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of complement activation." [GOC:go_curators] xref: GO:0030449 is_a: CCO:P0001246 ! regulation of proteolysis [Term] id: CCO:P0001264 name: regulation of complement activation, classical pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the classical pathway of complement activation." [GOC:go_curators] xref: GO:0030450 is_a: CCO:P0001263 ! regulation of complement activation [Term] id: CCO:P0001265 name: regulation of complement activation, alternative pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation." [GOC:go_curators] xref: GO:0030451 is_a: CCO:P0001263 ! regulation of complement activation [Term] id: CCO:P0001266 name: chromatin silencing at silent mating-type cassette namespace: biological_process def: "Repression of transcription at silent mating-type loci by the formation of heterochromatin." [GOC:mcc] synonym: "aging-dependent sterility (sensu Fungi)" RELATED [] synonym: "aging-dependent sterility (sensu Saccharomyces)" RELATED [] synonym: "chromatin silencing at HML and HMR (sensu Saccharomyces)" NARROW [] synonym: "chromatin silencing at silent mating-type cassette (sensu Fungi)" EXACT [] synonym: "heterochromatic silencing at silent mating-type cassette" EXACT [] xref: GO:0006347 xref: GO:0030466 is_a: CCO:P0000648 ! chromatin silencing [Term] id: CCO:P0001267 name: ascospore wall assembly namespace: biological_process def: "The process by which the ascospore nucleus becomes surrounded by a specialized spore wall. Occurs by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane." [GOC:mcc, PMID:14702385] synonym: "spore wall assembly (sensu Fungi)" EXACT [] synonym: "spore wall assembly (sensu Saccharomyces)" NARROW [] xref: GO:0007152 xref: GO:0030476 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001262 ! ascospore formation [Term] id: CCO:P0001268 name: heteroduplex formation namespace: biological_process def: "The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules." [GOC:elh, PMID:10357855] xref: GO:0030491 xref: Reactome:76007 xref: Reactome:76008 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000799 ! gene conversion at mating-type locus [Term] id: CCO:P0001269 name: regulation of cell redox homeostasis namespace: biological_process def: "Any process that modulates the redox environment of a cell or compartment within a cell." [GOC:mah] subset: gosubset_prok synonym: "regulation of redox homeostasis" BROAD [] xref: GO:0030503 xref: GO:0045867 xref: GO:0045868 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0029357 ! EGLN2_HUMAN relationship: has_participant CCO:B0054910 ! GPX1_HUMAN relationship: has_participant CCO:B0055194 ! APEX1_HUMAN relationship: has_participant CCO:B0055404 ! GSH1_HUMAN relationship: has_participant CCO:B0058480 ! SELS_HUMAN relationship: has_participant CCO:B0058502 ! TXND4_HUMAN relationship: has_participant CCO:B0058907 ! GLRX2_HUMAN [Term] id: CCO:P0001270 name: BMP signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor." [ISBN:0878932437] synonym: "BMP receptor signaling pathway" RELATED [] synonym: "BMP signalling pathway" EXACT [] synonym: "bone morphogenetic protein signaling pathway" EXACT [] synonym: "bone morphogenetic protein signalling pathway" EXACT [] xref: GO:0030509 is_a: CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0001516 ! BMP4_HUMAN relationship: has_participant CCO:B0001531 ! BMP7_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0001767 ! BMPR2_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005328 ! NOGG_HUMAN relationship: has_participant CCO:B0005437 ! BMR1A_HUMAN relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN relationship: has_participant CCO:B0019461 ! UB2D3_HUMAN relationship: has_participant CCO:B0019462 ! UB2D1_HUMAN relationship: has_participant CCO:B0020371 ! BMR1B_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: has_participant CCO:B0042130 ! BMP6_HUMAN relationship: has_participant CCO:B0054406 ! SMAD7_HUMAN relationship: has_participant CCO:B0054414 ! SMAD9_HUMAN relationship: has_participant CCO:B0054488 ! SMAD6_HUMAN relationship: has_participant CCO:B0054795 ! CER1_HUMAN relationship: has_participant CCO:B0055004 ! SKI_HUMAN relationship: has_participant CCO:B0055083 ! ZNF8_HUMAN relationship: has_participant CCO:B0055848 ! FSTL1_HUMAN relationship: has_participant CCO:B0055940 ! AVR2B_HUMAN relationship: has_participant CCO:B0056114 ! SMAD1_HUMAN relationship: has_participant CCO:B0056834 ! GDF6_HUMAN relationship: has_participant CCO:B0056863 ! RGMB_HUMAN relationship: has_participant CCO:B0057155 ! ZFY16_HUMAN relationship: has_participant CCO:B0058446 ! SMAD5_HUMAN relationship: has_participant CCO:B0058518 ! CRDL1_HUMAN relationship: has_participant CCO:B0058643 ! TWSG1_HUMAN relationship: has_participant CCO:B0058739 ! GREM2_HUMAN relationship: has_participant CCO:B0058768 ! SMUF2_HUMAN relationship: has_participant CCO:B0058805 ! SMUF1_HUMAN relationship: has_participant CCO:B0059181 ! GDF2_HUMAN [Term] id: CCO:P0001271 name: regulation of BMP signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway." [GOC:mah] synonym: "regulation of BMP receptor signaling pathway" RELATED [] synonym: "regulation of BMP signalling pathway" EXACT [] synonym: "regulation of bone morphogenetic protein signaling pathway" EXACT [] synonym: "regulation of bone morphogenetic protein signalling pathway" EXACT [] xref: GO:0030510 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0023795 ! PCSK6_HUMAN relationship: regulates CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:P0001272 name: positive regulation of transforming growth factor beta receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of TGFbeta receptor signaling pathway activity." [GOC:go_curators] synonym: "activation of transforming growth factor beta receptor signaling pathway" NARROW [] synonym: "positive regulation of TGF-beta receptor signaling pathway" EXACT [] synonym: "positive regulation of TGFbeta receptor signaling pathway" EXACT [] synonym: "positive regulation of transforming growth factor beta receptor signalling pathway" EXACT [] synonym: "stimulation of transforming growth factor beta receptor signaling pathway" NARROW [] synonym: "up regulation of transforming growth factor beta receptor signaling pathway" EXACT [] synonym: "up-regulation of transforming growth factor beta receptor signaling pathway" EXACT [] synonym: "upregulation of transforming growth factor beta receptor signaling pathway" EXACT [] xref: GO:0030511 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0002130 ! HIPK2_HUMAN relationship: has_participant CCO:B0026213 ! ITA8_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: positively_regulates CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0001273 name: negative regulation of transforming growth factor beta receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of any TGFbeta receptor signaling pathway." [GOC:mah] synonym: "down regulation of transforming growth factor beta receptor signaling pathway" EXACT [] synonym: "down-regulation of transforming growth factor beta receptor signaling pathway" EXACT [] synonym: "downregulation of transforming growth factor beta receptor signaling pathway" EXACT [] synonym: "inhibition of transforming growth factor beta receptor signaling pathway" NARROW [] synonym: "negative regulation of TGF-beta receptor signaling pathway" EXACT [] synonym: "negative regulation of TGFbeta receptor signaling pathway" EXACT [] synonym: "negative regulation of transforming growth factor beta receptor signalling pathway" EXACT [] xref: GO:0030512 xref: Reactome:173481 xref: Reactome:173512 xref: Reactome:209023 xref: Reactome:211004 xref: Reactome:218684 xref: Reactome:220848 xref: Reactome:235817 xref: Reactome:237538 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001132 ! regulation of transforming growth factor beta receptor signaling pathway relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0026583 ! SNX6_HUMAN relationship: has_participant CCO:B0054566 ! CIDEA_HUMAN relationship: has_participant CCO:B0057490 ! EID2_HUMAN relationship: has_participant CCO:B0058087 ! HTRA1_HUMAN relationship: negatively_regulates CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0001274 name: positive regulation of BMP signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity." [GOC:go_curators] synonym: "activation of BMP signaling pathway" NARROW [] synonym: "positive regulation of BMP receptor signaling pathway" RELATED [] synonym: "positive regulation of BMP signalling pathway" EXACT [] synonym: "positive regulation of bone morphogenetic protein signaling pathway" EXACT [] synonym: "positive regulation of bone morphogenetic protein signalling pathway" EXACT [] synonym: "stimulation of BMP signaling pathway" NARROW [] synonym: "up regulation of BMP signaling pathway" EXACT [] synonym: "up-regulation of BMP signaling pathway" EXACT [] synonym: "upregulation of BMP signaling pathway" EXACT [] xref: GO:0030513 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001271 ! regulation of BMP signaling pathway relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0055092 ! EGLN_HUMAN relationship: has_participant CCO:B0058643 ! TWSG1_HUMAN relationship: positively_regulates CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:P0001275 name: negative regulation of BMP signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway activity." [GOC:go_curators] synonym: "down regulation of BMP signaling pathway" EXACT [] synonym: "down-regulation of BMP signaling pathway" EXACT [] synonym: "downregulation of BMP signaling pathway" EXACT [] synonym: "inhibition of BMP signaling pathway" NARROW [] synonym: "negative regulation of BMP receptor signaling pathway" RELATED [] synonym: "negative regulation of BMP signalling pathway" EXACT [] synonym: "negative regulation of bone morphogenetic protein signaling pathway" EXACT [] synonym: "negative regulation of bone morphogenetic protein signalling pathway" EXACT [] xref: GO:0030514 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001271 ! regulation of BMP signaling pathway relationship: has_participant CCO:B0005328 ! NOGG_HUMAN relationship: has_participant CCO:B0025823 ! TOB1_HUMAN relationship: has_participant CCO:B0054778 ! FSTL3_HUMAN relationship: has_participant CCO:B0054795 ! CER1_HUMAN relationship: has_participant CCO:B0056226 ! VWC2_HUMAN relationship: has_participant CCO:B0057526 ! BMPER_HUMAN relationship: has_participant CCO:B0058087 ! HTRA1_HUMAN relationship: has_participant CCO:B0058479 ! SOST_HUMAN relationship: has_participant CCO:B0058643 ! TWSG1_HUMAN relationship: has_participant CCO:B0058805 ! SMUF1_HUMAN relationship: negatively_regulates CCO:P0001270 ! BMP signaling pathway [Term] id: CCO:P0001276 name: regulation of axon extension namespace: biological_process def: "Any process that modulates the rate, direction or extent of axon extension." [GOC:go_curators] xref: GO:0030516 is_a: CCO:P0002948 ! regulation of axonogenesis relationship: has_participant CCO:B0015672 ! NRCAM_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0057614 ! TTL_HUMAN relationship: has_participant CCO:B0058958 ! BARH2_HUMAN [Term] id: CCO:P0001277 name: negative regulation of axon extension namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axon outgrowth." [GOC:mah] synonym: "down regulation of axon extension" EXACT [] synonym: "down-regulation of axon extension" EXACT [] synonym: "downregulation of axon extension" EXACT [] synonym: "inhibition of axon extension" NARROW [] xref: GO:0030517 is_a: CCO:P0001276 ! regulation of axon extension is_a: CCO:P0002949 ! negative regulation of axonogenesis relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0054777 ! NET1_HUMAN [Term] id: CCO:P0001278 name: steroid hormone receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor." [GOC:mah] synonym: "steroid hormone receptor signalling pathway" EXACT [] xref: GO:0030518 is_a: CCO:P0001281 ! intracellular receptor-mediated signaling pathway relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0054344 ! LPP1_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0057877 ! RHXF1_HUMAN relationship: has_participant CCO:B0059047 ! CACO1_HUMAN relationship: has_participant CCO:B0059320 ! TR150_HUMAN [Term] id: CCO:P0001279 name: estrogen receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of an estrogen binding to its receptor." [GOC:mah] synonym: "estrogen receptor signalling pathway" EXACT [] xref: GO:0030520 is_a: CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN relationship: has_participant CCO:B0029357 ! EGLN2_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN relationship: has_participant CCO:B0056073 ! TAF7_HUMAN relationship: has_participant CCO:B0057308 ! PRGC2_HUMAN relationship: has_participant CCO:B0057889 ! Q8TAL0_HUMAN relationship: has_participant CCO:B0057925 ! DDX54_HUMAN relationship: has_participant CCO:B0058084 ! ESR2_HUMAN relationship: has_participant CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:P0001280 name: androgen receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of an androgen binding to its receptor." [GOC:mah] synonym: "androgen receptor signalling pathway" EXACT [] xref: GO:0030521 is_a: CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0005277 ! MED4_HUMAN relationship: has_participant CCO:B0005321 ! PIAS2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005791 ! MED16_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005797 ! MED30_HUMAN relationship: has_participant CCO:B0005799 ! MED24_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005830 ! FHL2_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0017844 ! TGFI1_HUMAN relationship: has_participant CCO:B0041593 ! NCOA4_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN relationship: has_participant CCO:B0049848 ! RNF4_HUMAN relationship: has_participant CCO:B0054344 ! LPP1_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN relationship: has_participant CCO:B0056112 ! NCOA1_HUMAN relationship: has_participant CCO:B0057594 ! Q8NER4_HUMAN relationship: has_participant CCO:B0058144 ! PMEPA_HUMAN relationship: has_participant CCO:B0059083 ! RNF14_HUMAN relationship: has_participant CCO:B0059320 ! TR150_HUMAN relationship: has_participant CCO:B0059343 ! GRIP1_HUMAN relationship: has_participant CCO:B0059357 ! JHD2A_HUMAN [Term] id: CCO:P0001281 name: intracellular receptor-mediated signaling pathway namespace: biological_process def: "Any series of molecular signals initiated by a ligand entering the target cell, where it binds to an intracellular receptor." [GOC:mah] synonym: "intracellular receptor-mediated signalling pathway" EXACT [] xref: GO:0030522 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0022559 ! SLAP2_HUMAN relationship: has_participant CCO:B0058328 ! DCBD2_HUMAN [Term] id: CCO:P0001282 name: ubiquitin-dependent SMAD protein catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome." [GOC:go_curators] synonym: "ubiquitin-dependent SMAD protein breakdown" EXACT [] synonym: "ubiquitin-dependent SMAD protein catabolism" EXACT [] synonym: "ubiquitin-dependent SMAD protein degradation" EXACT [] xref: GO:0030579 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0059251 ! STUB1_HUMAN relationship: part_of CCO:P0000720 ! transforming growth factor beta receptor signaling pathway [Term] id: CCO:P0001283 name: lysine methylamine methyltransferase cofactor adduct incorporation namespace: biological_process def: "The incorporation of a lysine methylamine methyltransferase cofactor adduct into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. The lysine methylamine methyltransferase cofactor adduct is synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases." [PMID:11435424, RESID:AA0321] subset: gosubset_prok xref: GO:0030631 xref: RESID:AA0321 is_a: CCO:P0000666 ! translational readthrough [Term] id: CCO:P0001284 name: regulation of vitamin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:mah] subset: gosubset_prok synonym: "regulation of vitamin metabolism" EXACT [] xref: GO:0030656 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001285 name: chromatin silencing at centromere namespace: biological_process def: "Repression of transcription of centromeric DNA by the formation of heterochromatin." [GOC:mah] synonym: "heterochromatic silencing at centromere" EXACT [] xref: GO:0030702 is_a: CCO:P0000648 ! chromatin silencing [Term] id: CCO:P0001286 name: border follicle cell delamination namespace: biological_process def: "The splitting off of border cells from the anterior epithelium, prior to border cell migration." [PMID:10822261] synonym: "border cell delamination" BROAD [] xref: GO:0030709 is_a: CCO:P0003288 ! delamination [Term] id: CCO:P0001287 name: regulation of border follicle cell delamination namespace: biological_process def: "Any process that regulates the frequency, rate or extent of border cell delamination." [PMID:10822261] synonym: "regulation of border cell delamination" BROAD [] xref: GO:0030710 is_a: CCO:U0000002 ! biological process relationship: regulates CCO:P0001286 ! border follicle cell delamination [Term] id: CCO:P0001288 name: positive regulation of border follicle cell delamination namespace: biological_process def: "Any process that increases the frequency, rate or extent of border cell delamination." [PMID:10822261] synonym: "activation of border follicle cell delamination" NARROW [] synonym: "positive regulation of border cell delamination" BROAD [] synonym: "stimulation of border follicle cell delamination" NARROW [] synonym: "up regulation of border follicle cell delamination" EXACT [] synonym: "up-regulation of border follicle cell delamination" EXACT [] synonym: "upregulation of border follicle cell delamination" EXACT [] xref: GO:0030711 is_a: CCO:P0001287 ! regulation of border follicle cell delamination relationship: positively_regulates CCO:P0001286 ! border follicle cell delamination [Term] id: CCO:P0001289 name: negative regulation of border follicle cell delamination namespace: biological_process def: "Any process that decreases the frequency, rate or extent of border cell delamination." [PMID:10822261] synonym: "down regulation of border follicle cell delamination" EXACT [] synonym: "down-regulation of border follicle cell delamination" EXACT [] synonym: "downregulation of border follicle cell delamination" EXACT [] synonym: "inhibition of border follicle cell delamination" NARROW [] synonym: "negative regulation of border cell delamination" BROAD [] xref: GO:0030712 is_a: CCO:P0001287 ! regulation of border follicle cell delamination relationship: negatively_regulates CCO:P0001286 ! border follicle cell delamination [Term] id: CCO:P0001290 name: germ-line stem cell maintenance namespace: biological_process def: "Any process involved in preventing uncommitted germ-line stem cells from differentiating as another cell type." [ISBN:0879694238] xref: GO:0030718 is_a: CCO:P0001147 ! stem cell maintenance [Term] id: CCO:P0001291 name: germarium-derived female germ-line cyst formation namespace: biological_process def: "Formation of a cluster of germ-line cells, in the germarium, derived from a single founder cell (cystoblast)." [GOC:mtg_sensu, PMID:10370240] synonym: "female germ-line cyst formation (sensu Insecta)" EXACT [] xref: GO:0030727 is_a: CCO:P0002776 ! female germ-line cyst formation [Term] id: CCO:P0001292 name: regulation of cyclic nucleotide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "regulation of cyclic nucleotide metabolism" EXACT [] xref: GO:0030799 is_a: CCO:P0000625 ! regulation of nucleotide metabolic process [Term] id: CCO:P0001293 name: negative regulation of cyclic nucleotide metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cyclic nucleotide metabolic process" EXACT [] synonym: "down-regulation of cyclic nucleotide metabolic process" EXACT [] synonym: "downregulation of cyclic nucleotide metabolic process" EXACT [] synonym: "inhibition of cyclic nucleotide metabolic process" NARROW [] synonym: "negative regulation of cyclic nucleotide metabolism" EXACT [] xref: GO:0030800 is_a: CCO:P0001292 ! regulation of cyclic nucleotide metabolic process is_a: CCO:P0002656 ! negative regulation of nucleotide metabolic process [Term] id: CCO:P0001294 name: positive regulation of cyclic nucleotide metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "activation of cyclic nucleotide metabolic process" NARROW [] synonym: "positive regulation of cyclic nucleotide metabolism" EXACT [] synonym: "stimulation of cyclic nucleotide metabolic process" NARROW [] synonym: "up regulation of cyclic nucleotide metabolic process" EXACT [] synonym: "up-regulation of cyclic nucleotide metabolic process" EXACT [] synonym: "upregulation of cyclic nucleotide metabolic process" EXACT [] xref: GO:0030801 is_a: CCO:P0001292 ! regulation of cyclic nucleotide metabolic process is_a: CCO:P0002657 ! positive regulation of nucleotide metabolic process [Term] id: CCO:P0001295 name: regulation of cyclic nucleotide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "regulation of cyclic nucleotide anabolism" EXACT [] synonym: "regulation of cyclic nucleotide biosynthesis" EXACT [] synonym: "regulation of cyclic nucleotide formation" EXACT [] synonym: "regulation of cyclic nucleotide synthesis" EXACT [] xref: GO:0030802 is_a: CCO:P0001292 ! regulation of cyclic nucleotide metabolic process is_a: CCO:P0001301 ! regulation of nucleotide biosynthetic process [Term] id: CCO:P0001296 name: negative regulation of cyclic nucleotide biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cyclic nucleotide biosynthetic process" EXACT [] synonym: "down-regulation of cyclic nucleotide biosynthetic process" EXACT [] synonym: "downregulation of cyclic nucleotide biosynthetic process" EXACT [] synonym: "inhibition of cyclic nucleotide biosynthetic process" NARROW [] synonym: "negative regulation of cyclic nucleotide anabolism" EXACT [] synonym: "negative regulation of cyclic nucleotide biosynthesis" EXACT [] synonym: "negative regulation of cyclic nucleotide formation" EXACT [] synonym: "negative regulation of cyclic nucleotide synthesis" EXACT [] xref: GO:0030803 is_a: CCO:P0001293 ! negative regulation of cyclic nucleotide metabolic process is_a: CCO:P0001295 ! regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001302 ! negative regulation of nucleotide biosynthetic process [Term] id: CCO:P0001297 name: positive regulation of cyclic nucleotide biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "activation of cyclic nucleotide biosynthetic process" NARROW [] synonym: "positive regulation of cyclic nucleotide anabolism" EXACT [] synonym: "positive regulation of cyclic nucleotide biosynthesis" EXACT [] synonym: "positive regulation of cyclic nucleotide formation" EXACT [] synonym: "positive regulation of cyclic nucleotide synthesis" EXACT [] synonym: "stimulation of cyclic nucleotide biosynthetic process" NARROW [] synonym: "up regulation of cyclic nucleotide biosynthetic process" EXACT [] synonym: "up-regulation of cyclic nucleotide biosynthetic process" EXACT [] synonym: "upregulation of cyclic nucleotide biosynthetic process" EXACT [] xref: GO:0030804 is_a: CCO:P0001294 ! positive regulation of cyclic nucleotide metabolic process is_a: CCO:P0001295 ! regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001303 ! positive regulation of nucleotide biosynthetic process [Term] id: CCO:P0001298 name: regulation of cyclic nucleotide catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "regulation of cyclic nucleotide breakdown" EXACT [] synonym: "regulation of cyclic nucleotide catabolism" EXACT [] synonym: "regulation of cyclic nucleotide degradation" EXACT [] xref: GO:0030805 is_a: CCO:P0001292 ! regulation of cyclic nucleotide metabolic process is_a: CCO:P0001304 ! regulation of nucleotide catabolic process [Term] id: CCO:P0001299 name: negative regulation of cyclic nucleotide catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cyclic nucleotide catabolic process" EXACT [] synonym: "down-regulation of cyclic nucleotide catabolic process" EXACT [] synonym: "downregulation of cyclic nucleotide catabolic process" EXACT [] synonym: "inhibition of cyclic nucleotide catabolic process" NARROW [] synonym: "negative regulation of cyclic nucleotide breakdown" EXACT [] synonym: "negative regulation of cyclic nucleotide catabolism" EXACT [] synonym: "negative regulation of cyclic nucleotide degradation" EXACT [] xref: GO:0030806 is_a: CCO:P0001293 ! negative regulation of cyclic nucleotide metabolic process is_a: CCO:P0001298 ! regulation of cyclic nucleotide catabolic process is_a: CCO:P0001305 ! negative regulation of nucleotide catabolic process [Term] id: CCO:P0001300 name: positive regulation of cyclic nucleotide catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides." [GOC:mah] subset: gosubset_prok synonym: "activation of cyclic nucleotide catabolic process" NARROW [] synonym: "positive regulation of cyclic nucleotide breakdown" EXACT [] synonym: "positive regulation of cyclic nucleotide catabolism" EXACT [] synonym: "positive regulation of cyclic nucleotide degradation" EXACT [] synonym: "stimulation of cyclic nucleotide catabolic process" NARROW [] synonym: "up regulation of cyclic nucleotide catabolic process" EXACT [] synonym: "up-regulation of cyclic nucleotide catabolic process" EXACT [] synonym: "upregulation of cyclic nucleotide catabolic process" EXACT [] xref: GO:0030807 is_a: CCO:P0001294 ! positive regulation of cyclic nucleotide metabolic process is_a: CCO:P0001298 ! regulation of cyclic nucleotide catabolic process is_a: CCO:P0001306 ! positive regulation of nucleotide catabolic process [Term] id: CCO:P0001301 name: regulation of nucleotide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides." [GOC:mah] subset: gosubset_prok synonym: "regulation of nucleotide anabolism" EXACT [] synonym: "regulation of nucleotide biosynthesis" EXACT [] synonym: "regulation of nucleotide formation" EXACT [] synonym: "regulation of nucleotide synthesis" EXACT [] xref: GO:0030808 is_a: CCO:P0000625 ! regulation of nucleotide metabolic process is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0001302 name: negative regulation of nucleotide biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides." [GOC:mah] subset: gosubset_prok synonym: "down regulation of nucleotide biosynthetic process" EXACT [] synonym: "down-regulation of nucleotide biosynthetic process" EXACT [] synonym: "downregulation of nucleotide biosynthetic process" EXACT [] synonym: "inhibition of nucleotide biosynthetic process" NARROW [] synonym: "negative regulation of nucleotide anabolism" EXACT [] synonym: "negative regulation of nucleotide biosynthesis" EXACT [] synonym: "negative regulation of nucleotide formation" EXACT [] synonym: "negative regulation of nucleotide synthesis" EXACT [] xref: GO:0030809 is_a: CCO:P0001301 ! regulation of nucleotide biosynthetic process is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0002656 ! negative regulation of nucleotide metabolic process [Term] id: CCO:P0001303 name: positive regulation of nucleotide biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides." [GOC:mah] subset: gosubset_prok synonym: "activation of nucleotide biosynthetic process" NARROW [] synonym: "positive regulation of nucleotide anabolism" EXACT [] synonym: "positive regulation of nucleotide biosynthesis" EXACT [] synonym: "positive regulation of nucleotide formation" EXACT [] synonym: "positive regulation of nucleotide synthesis" EXACT [] synonym: "stimulation of nucleotide biosynthetic process" NARROW [] synonym: "up regulation of nucleotide biosynthetic process" EXACT [] synonym: "up-regulation of nucleotide biosynthetic process" EXACT [] synonym: "upregulation of nucleotide biosynthetic process" EXACT [] xref: GO:0030810 is_a: CCO:P0001301 ! regulation of nucleotide biosynthetic process is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0002657 ! positive regulation of nucleotide metabolic process [Term] id: CCO:P0001304 name: regulation of nucleotide catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides." [GOC:mah] subset: gosubset_prok synonym: "regulation of nucleotide breakdown" EXACT [] synonym: "regulation of nucleotide catabolism" EXACT [] synonym: "regulation of nucleotide degradation" EXACT [] xref: GO:0030811 is_a: CCO:P0000625 ! regulation of nucleotide metabolic process is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0001305 name: negative regulation of nucleotide catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides." [GOC:mah] subset: gosubset_prok synonym: "down regulation of nucleotide catabolic process" EXACT [] synonym: "down-regulation of nucleotide catabolic process" EXACT [] synonym: "downregulation of nucleotide catabolic process" EXACT [] synonym: "inhibition of nucleotide catabolic process" NARROW [] synonym: "negative regulation of nucleotide breakdown" EXACT [] synonym: "negative regulation of nucleotide catabolism" EXACT [] synonym: "negative regulation of nucleotide degradation" EXACT [] xref: GO:0030812 is_a: CCO:P0001304 ! regulation of nucleotide catabolic process is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0002656 ! negative regulation of nucleotide metabolic process [Term] id: CCO:P0001306 name: positive regulation of nucleotide catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides." [GOC:mah] subset: gosubset_prok synonym: "activation of nucleotide catabolic process" NARROW [] synonym: "positive regulation of nucleotide breakdown" EXACT [] synonym: "positive regulation of nucleotide catabolism" EXACT [] synonym: "positive regulation of nucleotide degradation" EXACT [] synonym: "stimulation of nucleotide catabolic process" NARROW [] synonym: "up regulation of nucleotide catabolic process" EXACT [] synonym: "up-regulation of nucleotide catabolic process" EXACT [] synonym: "upregulation of nucleotide catabolic process" EXACT [] xref: GO:0030813 is_a: CCO:P0001304 ! regulation of nucleotide catabolic process is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0002657 ! positive regulation of nucleotide metabolic process [Term] id: CCO:P0001307 name: regulation of cAMP metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "regulation of 3',5' cAMP metabolic process" EXACT [] synonym: "regulation of 3',5' cAMP metabolism" EXACT [] synonym: "regulation of 3',5'-cAMP metabolic process" EXACT [] synonym: "regulation of 3',5'-cAMP metabolism" EXACT [] synonym: "regulation of adenosine 3',5'-cyclophosphate metabolic process" EXACT [] synonym: "regulation of adenosine 3',5'-cyclophosphate metabolism" EXACT [] synonym: "regulation of cAMP metabolism" EXACT [] synonym: "regulation of cyclic AMP metabolic process" EXACT [] synonym: "regulation of cyclic AMP metabolism" EXACT [] xref: GO:0030814 is_a: CCO:P0001292 ! regulation of cyclic nucleotide metabolic process relationship: has_participant CCO:B0055046 ! TIMP2_HUMAN [Term] id: CCO:P0001308 name: negative regulation of cAMP metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cAMP metabolic process" EXACT [] synonym: "down-regulation of cAMP metabolic process" EXACT [] synonym: "downregulation of cAMP metabolic process" EXACT [] synonym: "inhibition of cAMP metabolic process" NARROW [] synonym: "negative regulation of 3',5' cAMP metabolic process" EXACT [] synonym: "negative regulation of 3',5' cAMP metabolism" EXACT [] synonym: "negative regulation of 3',5'-cAMP metabolic process" EXACT [] synonym: "negative regulation of 3',5'-cAMP metabolism" EXACT [] synonym: "negative regulation of adenosine 3',5'-cyclophosphate metabolic process" EXACT [] synonym: "negative regulation of adenosine 3',5'-cyclophosphate metabolism" EXACT [] synonym: "negative regulation of cAMP metabolism" EXACT [] synonym: "negative regulation of cyclic AMP metabolic process" EXACT [] synonym: "negative regulation of cyclic AMP metabolism" EXACT [] xref: GO:0030815 is_a: CCO:P0001293 ! negative regulation of cyclic nucleotide metabolic process is_a: CCO:P0001307 ! regulation of cAMP metabolic process [Term] id: CCO:P0001309 name: positive regulation of cAMP metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "activation of cAMP metabolic process" NARROW [] synonym: "positive regulation of 3',5' cAMP metabolic process" EXACT [] synonym: "positive regulation of 3',5' cAMP metabolism" EXACT [] synonym: "positive regulation of 3',5'-cAMP metabolic process" EXACT [] synonym: "positive regulation of 3',5'-cAMP metabolism" EXACT [] synonym: "positive regulation of adenosine 3',5'-cyclophosphate metabolic process" EXACT [] synonym: "positive regulation of adenosine 3',5'-cyclophosphate metabolism" EXACT [] synonym: "positive regulation of cAMP metabolism" EXACT [] synonym: "positive regulation of cyclic AMP metabolic process" EXACT [] synonym: "positive regulation of cyclic AMP metabolism" EXACT [] synonym: "stimulation of cAMP metabolic process" NARROW [] synonym: "up regulation of cAMP metabolic process" EXACT [] synonym: "up-regulation of cAMP metabolic process" EXACT [] synonym: "upregulation of cAMP metabolic process" EXACT [] xref: GO:0030816 is_a: CCO:P0001294 ! positive regulation of cyclic nucleotide metabolic process is_a: CCO:P0001307 ! regulation of cAMP metabolic process [Term] id: CCO:P0001310 name: regulation of cAMP biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "regulation of 3',5' cAMP biosynthesis" EXACT [] synonym: "regulation of 3',5' cAMP biosynthetic process" EXACT [] synonym: "regulation of 3',5'-cAMP biosynthesis" EXACT [] synonym: "regulation of 3',5'-cAMP biosynthetic process" EXACT [] synonym: "regulation of adenosine 3',5'-cyclophosphate biosynthesis" EXACT [] synonym: "regulation of adenosine 3',5'-cyclophosphate biosynthetic process" EXACT [] synonym: "regulation of cAMP anabolism" EXACT [] synonym: "regulation of cAMP biosynthesis" EXACT [] synonym: "regulation of cAMP formation" EXACT [] synonym: "regulation of cAMP synthesis" EXACT [] synonym: "regulation of cyclic AMP biosynthesis" EXACT [] synonym: "regulation of cyclic AMP biosynthetic process" EXACT [] xref: GO:0030817 is_a: CCO:P0001295 ! regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001307 ! regulation of cAMP metabolic process relationship: has_participant CCO:B0057933 ! OXER1_HUMAN [Term] id: CCO:P0001311 name: negative regulation of cAMP biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cAMP biosynthetic process" EXACT [] synonym: "down-regulation of cAMP biosynthetic process" EXACT [] synonym: "downregulation of cAMP biosynthetic process" EXACT [] synonym: "inhibition of cAMP biosynthetic process" NARROW [] synonym: "negative regulation of 3',5' cAMP biosynthesis" EXACT [] synonym: "negative regulation of 3',5' cAMP biosynthetic process" EXACT [] synonym: "negative regulation of 3',5'-cAMP biosynthesis" EXACT [] synonym: "negative regulation of 3',5'-cAMP biosynthetic process" EXACT [] synonym: "negative regulation of adenosine 3',5'-cyclophosphate biosynthesis" EXACT [] synonym: "negative regulation of adenosine 3',5'-cyclophosphate biosynthetic process" EXACT [] synonym: "negative regulation of cAMP anabolism" EXACT [] synonym: "negative regulation of cAMP biosynthesis" EXACT [] synonym: "negative regulation of cAMP formation" EXACT [] synonym: "negative regulation of cAMP synthesis" EXACT [] synonym: "negative regulation of cyclic AMP biosynthesis" EXACT [] synonym: "negative regulation of cyclic AMP biosynthetic process" EXACT [] xref: GO:0030818 is_a: CCO:P0001296 ! negative regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001308 ! negative regulation of cAMP metabolic process is_a: CCO:P0001310 ! regulation of cAMP biosynthetic process relationship: has_participant CCO:B0042241 ! GRM8_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN [Term] id: CCO:P0001312 name: positive regulation of cAMP biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "activation of cAMP biosynthetic process" NARROW [] synonym: "positive regulation of 3',5' cAMP biosynthesis" EXACT [] synonym: "positive regulation of 3',5' cAMP biosynthetic process" EXACT [] synonym: "positive regulation of 3',5'-cAMP biosynthesis" EXACT [] synonym: "positive regulation of 3',5'-cAMP biosynthetic process" EXACT [] synonym: "positive regulation of adenosine 3',5'-cyclophosphate biosynthesis" EXACT [] synonym: "positive regulation of adenosine 3',5'-cyclophosphate biosynthetic process" EXACT [] synonym: "positive regulation of cAMP anabolism" EXACT [] synonym: "positive regulation of cAMP biosynthesis" EXACT [] synonym: "positive regulation of cAMP formation" EXACT [] synonym: "positive regulation of cAMP synthesis" EXACT [] synonym: "positive regulation of cyclic AMP biosynthesis" EXACT [] synonym: "positive regulation of cyclic AMP biosynthetic process" EXACT [] synonym: "stimulation of cAMP biosynthetic process" NARROW [] synonym: "up regulation of cAMP biosynthetic process" EXACT [] synonym: "up-regulation of cAMP biosynthetic process" EXACT [] synonym: "upregulation of cAMP biosynthetic process" EXACT [] xref: GO:0030819 is_a: CCO:P0001297 ! positive regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001309 ! positive regulation of cAMP metabolic process is_a: CCO:P0001310 ! regulation of cAMP biosynthetic process relationship: has_participant CCO:B0017140 ! NEU2_HUMAN relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN [Term] id: CCO:P0001313 name: regulation of cAMP catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "regulation of 3',5' cAMP catabolic process" EXACT [] synonym: "regulation of 3',5' cAMP catabolism" EXACT [] synonym: "regulation of 3',5'-cAMP catabolic process" EXACT [] synonym: "regulation of 3',5'-cAMP catabolism" EXACT [] synonym: "regulation of adenosine 3',5'-cyclophosphate catabolic process" EXACT [] synonym: "regulation of adenosine 3',5'-cyclophosphate catabolism" EXACT [] synonym: "regulation of cAMP breakdown" EXACT [] synonym: "regulation of cAMP catabolism" EXACT [] synonym: "regulation of cAMP degradation" EXACT [] synonym: "regulation of cyclic AMP catabolic process" EXACT [] synonym: "regulation of cyclic AMP catabolism" EXACT [] xref: GO:0030820 is_a: CCO:P0001298 ! regulation of cyclic nucleotide catabolic process is_a: CCO:P0001307 ! regulation of cAMP metabolic process [Term] id: CCO:P0001314 name: negative regulation of cAMP catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cAMP catabolic process" EXACT [] synonym: "down-regulation of cAMP catabolic process" EXACT [] synonym: "downregulation of cAMP catabolic process" EXACT [] synonym: "inhibition of cAMP catabolic process" NARROW [] synonym: "negative regulation of 3',5' cAMP catabolic process" EXACT [] synonym: "negative regulation of 3',5' cAMP catabolism" EXACT [] synonym: "negative regulation of 3',5'-cAMP catabolic process" EXACT [] synonym: "negative regulation of 3',5'-cAMP catabolism" EXACT [] synonym: "negative regulation of adenosine 3',5'-cyclophosphate catabolic process" EXACT [] synonym: "negative regulation of adenosine 3',5'-cyclophosphate catabolism" EXACT [] synonym: "negative regulation of cAMP breakdown" EXACT [] synonym: "negative regulation of cAMP catabolism" EXACT [] synonym: "negative regulation of cAMP degradation" EXACT [] synonym: "negative regulation of cyclic AMP catabolic process" EXACT [] synonym: "negative regulation of cyclic AMP catabolism" EXACT [] xref: GO:0030821 is_a: CCO:P0001299 ! negative regulation of cyclic nucleotide catabolic process is_a: CCO:P0001308 ! negative regulation of cAMP metabolic process is_a: CCO:P0001313 ! regulation of cAMP catabolic process [Term] id: CCO:P0001315 name: positive regulation of cAMP catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:mah] subset: gosubset_prok synonym: "activation of cAMP catabolic process" NARROW [] synonym: "positive regulation of 3',5' cAMP catabolic process" EXACT [] synonym: "positive regulation of 3',5' cAMP catabolism" EXACT [] synonym: "positive regulation of 3',5'-cAMP catabolic process" EXACT [] synonym: "positive regulation of 3',5'-cAMP catabolism" EXACT [] synonym: "positive regulation of adenosine 3',5'-cyclophosphate catabolic process" EXACT [] synonym: "positive regulation of adenosine 3',5'-cyclophosphate catabolism" EXACT [] synonym: "positive regulation of cAMP breakdown" EXACT [] synonym: "positive regulation of cAMP catabolism" EXACT [] synonym: "positive regulation of cAMP degradation" EXACT [] synonym: "positive regulation of cyclic AMP catabolic process" EXACT [] synonym: "positive regulation of cyclic AMP catabolism" EXACT [] synonym: "stimulation of cAMP catabolic process" NARROW [] synonym: "up regulation of cAMP catabolic process" EXACT [] synonym: "up-regulation of cAMP catabolic process" EXACT [] synonym: "upregulation of cAMP catabolic process" EXACT [] xref: GO:0030822 is_a: CCO:P0001300 ! positive regulation of cyclic nucleotide catabolic process is_a: CCO:P0001309 ! positive regulation of cAMP metabolic process is_a: CCO:P0001313 ! regulation of cAMP catabolic process [Term] id: CCO:P0001316 name: regulation of cGMP metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP." [GOC:mah] subset: gosubset_prok synonym: "regulation of cGMP metabolism" EXACT [] xref: GO:0030823 is_a: CCO:P0001292 ! regulation of cyclic nucleotide metabolic process [Term] id: CCO:P0001317 name: negative regulation of cGMP metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cGMP metabolic process" EXACT [] synonym: "down-regulation of cGMP metabolic process" EXACT [] synonym: "downregulation of cGMP metabolic process" EXACT [] synonym: "inhibition of cGMP metabolic process" NARROW [] synonym: "negative regulation of cGMP metabolism" EXACT [] xref: GO:0030824 is_a: CCO:P0001293 ! negative regulation of cyclic nucleotide metabolic process is_a: CCO:P0001316 ! regulation of cGMP metabolic process [Term] id: CCO:P0001318 name: positive regulation of cGMP metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP." [GOC:mah] subset: gosubset_prok synonym: "activation of cGMP metabolic process" NARROW [] synonym: "positive regulation of cGMP metabolism" EXACT [] synonym: "stimulation of cGMP metabolic process" NARROW [] synonym: "up regulation of cGMP metabolic process" EXACT [] synonym: "up-regulation of cGMP metabolic process" EXACT [] synonym: "upregulation of cGMP metabolic process" EXACT [] xref: GO:0030825 is_a: CCO:P0001294 ! positive regulation of cyclic nucleotide metabolic process is_a: CCO:P0001316 ! regulation of cGMP metabolic process [Term] id: CCO:P0001319 name: regulation of cGMP biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP." [GOC:mah] subset: gosubset_prok synonym: "regulation of cGMP anabolism" EXACT [] synonym: "regulation of cGMP biosynthesis" EXACT [] synonym: "regulation of cGMP formation" EXACT [] synonym: "regulation of cGMP synthesis" EXACT [] xref: GO:0030826 is_a: CCO:P0001295 ! regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001316 ! regulation of cGMP metabolic process [Term] id: CCO:P0001320 name: negative regulation of cGMP biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cGMP biosynthetic process" EXACT [] synonym: "down-regulation of cGMP biosynthetic process" EXACT [] synonym: "downregulation of cGMP biosynthetic process" EXACT [] synonym: "inhibition of cGMP biosynthetic process" NARROW [] synonym: "negative regulation of cGMP anabolism" EXACT [] synonym: "negative regulation of cGMP biosynthesis" EXACT [] synonym: "negative regulation of cGMP formation" EXACT [] synonym: "negative regulation of cGMP synthesis" EXACT [] xref: GO:0030827 is_a: CCO:P0001296 ! negative regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001317 ! negative regulation of cGMP metabolic process is_a: CCO:P0001319 ! regulation of cGMP biosynthetic process relationship: has_participant CCO:B0025070 ! PDZD3_HUMAN [Term] id: CCO:P0001321 name: positive regulation of cGMP biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP." [GOC:mah] subset: gosubset_prok synonym: "activation of cGMP biosynthetic process" NARROW [] synonym: "positive regulation of cGMP anabolism" EXACT [] synonym: "positive regulation of cGMP biosynthesis" EXACT [] synonym: "positive regulation of cGMP formation" EXACT [] synonym: "positive regulation of cGMP synthesis" EXACT [] synonym: "stimulation of cGMP biosynthetic process" NARROW [] synonym: "up regulation of cGMP biosynthetic process" EXACT [] synonym: "up-regulation of cGMP biosynthetic process" EXACT [] synonym: "upregulation of cGMP biosynthetic process" EXACT [] xref: GO:0030828 is_a: CCO:P0001297 ! positive regulation of cyclic nucleotide biosynthetic process is_a: CCO:P0001318 ! positive regulation of cGMP metabolic process is_a: CCO:P0001319 ! regulation of cGMP biosynthetic process relationship: has_participant CCO:B0054862 ! APOE_HUMAN [Term] id: CCO:P0001322 name: regulation of cGMP catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP." [GOC:mah] subset: gosubset_prok synonym: "regulation of cGMP breakdown" EXACT [] synonym: "regulation of cGMP catabolism" EXACT [] synonym: "regulation of cGMP degradation" EXACT [] xref: GO:0030829 is_a: CCO:P0001298 ! regulation of cyclic nucleotide catabolic process is_a: CCO:P0001316 ! regulation of cGMP metabolic process [Term] id: CCO:P0001323 name: negative regulation of cGMP catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cGMP catabolic process" EXACT [] synonym: "down-regulation of cGMP catabolic process" EXACT [] synonym: "downregulation of cGMP catabolic process" EXACT [] synonym: "inhibition of cGMP catabolic process" NARROW [] synonym: "negative regulation of cGMP breakdown" EXACT [] synonym: "negative regulation of cGMP catabolism" EXACT [] synonym: "negative regulation of cGMP degradation" EXACT [] xref: GO:0030830 is_a: CCO:P0001299 ! negative regulation of cyclic nucleotide catabolic process is_a: CCO:P0001317 ! negative regulation of cGMP metabolic process is_a: CCO:P0001322 ! regulation of cGMP catabolic process [Term] id: CCO:P0001324 name: positive regulation of cGMP catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP." [GOC:mah] subset: gosubset_prok synonym: "activation of cGMP catabolic process" NARROW [] synonym: "positive regulation of cGMP breakdown" EXACT [] synonym: "positive regulation of cGMP catabolism" EXACT [] synonym: "positive regulation of cGMP degradation" EXACT [] synonym: "stimulation of cGMP catabolic process" NARROW [] synonym: "up regulation of cGMP catabolic process" EXACT [] synonym: "up-regulation of cGMP catabolic process" EXACT [] synonym: "upregulation of cGMP catabolic process" EXACT [] xref: GO:0030831 is_a: CCO:P0001300 ! positive regulation of cyclic nucleotide catabolic process is_a: CCO:P0001318 ! positive regulation of cGMP metabolic process is_a: CCO:P0001322 ! regulation of cGMP catabolic process [Term] id: CCO:P0001325 name: regulation of actin filament length namespace: biological_process def: "Any process that controls the length of actin filaments in a cell." [GOC:dph, GOC:mah] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. xref: GO:0030832 is_a: CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis relationship: has_participant CCO:B0054689 ! NEBL_HUMAN relationship: has_participant CCO:B0055127 ! NEBU_HUMAN [Term] id: CCO:P0001326 name: regulation of actin filament polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament." [GOC:mah] synonym: "regulation of actin polymerization" EXACT [] xref: GO:0030833 is_a: CCO:P0000811 ! regulation of actin polymerization and/or depolymerization is_a: CCO:P0001575 ! regulation of protein polymerization relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0006172 ! ARPC3_HUMAN relationship: has_participant CCO:B0021495 ! Q96BT2_HUMAN relationship: has_participant CCO:B0021497 ! Q59GD5_HUMAN relationship: has_participant CCO:B0021502 ! ARP3_HUMAN relationship: has_participant CCO:B0021504 ! Q7Z526_HUMAN relationship: has_participant CCO:B0024096 ! Q9BXV5_HUMAN relationship: has_participant CCO:B0024099 ! ARPC2_HUMAN relationship: has_participant CCO:B0031593 ! ARC1B_HUMAN relationship: has_participant CCO:B0031598 ! ARC1A_HUMAN relationship: has_participant CCO:B0049611 ! ARP3B_HUMAN relationship: has_participant CCO:B0054026 ! A8MTG1_HUMAN relationship: has_participant CCO:B0054134 ! A8MYY8_HUMAN relationship: has_participant CCO:B0054238 ! B1ALC0_HUMAN relationship: has_participant CCO:B0054441 ! ARPC5_HUMAN relationship: has_participant CCO:B0056821 ! Q6IPM3_HUMAN relationship: has_participant CCO:B0058471 ! ARP5L_HUMAN relationship: has_participant CCO:B0058538 ! Q9BWW0_HUMAN relationship: has_participant CCO:B0058539 ! Q9BWW1_HUMAN relationship: has_participant CCO:B0058540 ! Q9BWW2_HUMAN relationship: has_participant CCO:B0058623 ! ARP11_HUMAN [Term] id: CCO:P0001327 name: regulation of actin filament depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament." [GOC:mah] synonym: "regulation of actin depolymerization" EXACT [] xref: GO:0030834 is_a: CCO:P0000811 ! regulation of actin polymerization and/or depolymerization [Term] id: CCO:P0001328 name: negative regulation of actin filament depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin depolymerization." [GOC:mah] comment: This term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin polymerization ; GO:0030837'). synonym: "actin filament stabilization" EXACT [] synonym: "down regulation of actin filament depolymerization" EXACT [] synonym: "down-regulation of actin filament depolymerization" EXACT [] synonym: "downregulation of actin filament depolymerization" EXACT [] synonym: "inhibition of actin filament depolymerization" NARROW [] synonym: "negative regulation of actin depolymerization" EXACT [] synonym: "negative regulation of actin polymerization and/or depolymerization" BROAD [] xref: GO:0030044 xref: GO:0030835 is_a: CCO:P0001327 ! regulation of actin filament depolymerization is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis relationship: has_participant CCO:B0059132 ! LIMA1_HUMAN [Term] id: CCO:P0001329 name: positive regulation of actin filament depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of actin depolymerization." [GOC:mah] comment: This term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin polymerization ; GO:0030838'). synonym: "actin filament destabilization" EXACT [] synonym: "activation of actin filament depolymerization" NARROW [] synonym: "positive regulation of actin depolymerization" EXACT [] synonym: "positive regulation of actin polymerization and/or depolymerization" BROAD [] synonym: "stimulation of actin filament depolymerization" NARROW [] synonym: "up regulation of actin filament depolymerization" EXACT [] synonym: "up-regulation of actin filament depolymerization" EXACT [] synonym: "upregulation of actin filament depolymerization" EXACT [] xref: GO:0030045 xref: GO:0030836 is_a: CCO:P0001327 ! regulation of actin filament depolymerization is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis relationship: has_participant CCO:B0033316 ! DEST_HUMAN [Term] id: CCO:P0001330 name: negative regulation of actin filament polymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin polymerization." [GOC:mah] comment: This term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin depolymerization ; GO:0030835'). synonym: "down regulation of actin filament polymerization" EXACT [] synonym: "down-regulation of actin filament polymerization" EXACT [] synonym: "downregulation of actin filament polymerization" EXACT [] synonym: "inhibition of actin filament polymerization" NARROW [] synonym: "negative regulation of actin polymerization" EXACT [] synonym: "negative regulation of actin polymerization and/or depolymerization" BROAD [] xref: GO:0030837 is_a: CCO:P0001326 ! regulation of actin filament polymerization is_a: CCO:P0001576 ! negative regulation of protein polymerization is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001331 name: positive regulation of actin filament polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of actin polymerization." [GOC:mah] comment: This term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin depolymerization ; GO:0030836'). synonym: "activation of actin filament polymerization" NARROW [] synonym: "positive regulation of actin polymerization" EXACT [] synonym: "positive regulation of actin polymerization and/or depolymerization" BROAD [] synonym: "stimulation of actin filament polymerization" NARROW [] synonym: "up regulation of actin filament polymerization" EXACT [] synonym: "up-regulation of actin filament polymerization" EXACT [] synonym: "upregulation of actin filament polymerization" EXACT [] xref: GO:0030838 is_a: CCO:P0001326 ! regulation of actin filament polymerization is_a: CCO:P0001577 ! positive regulation of protein polymerization is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis relationship: has_participant CCO:B0054357 ! BORG1_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0055616 ! ARF6_HUMAN relationship: has_participant CCO:B0056874 ! BORG3_HUMAN [Term] id: CCO:P0001332 name: regulation of intermediate filament polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament." [GOC:mah] xref: GO:0030839 is_a: CCO:P0001575 ! regulation of protein polymerization is_a: CCO:P0002279 ! regulation of intermediate filament polymerization and/or depolymerization [Term] id: CCO:P0001333 name: negative regulation of intermediate filament polymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intermediate filament polymerization." [GOC:mah] comment: This term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament depolymerization ; GO:0030843'). synonym: "down regulation of intermediate filament polymerization" EXACT [] synonym: "down-regulation of intermediate filament polymerization" EXACT [] synonym: "downregulation of intermediate filament polymerization" EXACT [] synonym: "inhibition of intermediate filament polymerization" NARROW [] synonym: "negative regulation of intermediate filament polymerization and/or depolymerization" BROAD [] xref: GO:0030840 is_a: CCO:P0001332 ! regulation of intermediate filament polymerization is_a: CCO:P0001576 ! negative regulation of protein polymerization is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001334 name: positive regulation of intermediate filament polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization." [GOC:mah] comment: This term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament depolymerization ; GO:0030844'). synonym: "activation of intermediate filament polymerization" NARROW [] synonym: "positive regulation of intermediate filament polymerization and/or depolymerization" BROAD [] synonym: "stimulation of intermediate filament polymerization" NARROW [] synonym: "up regulation of intermediate filament polymerization" EXACT [] synonym: "up-regulation of intermediate filament polymerization" EXACT [] synonym: "upregulation of intermediate filament polymerization" EXACT [] xref: GO:0030841 is_a: CCO:P0001332 ! regulation of intermediate filament polymerization is_a: CCO:P0001577 ! positive regulation of protein polymerization is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001335 name: regulation of intermediate filament depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament." [GOC:mah] xref: GO:0030842 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process is_a: CCO:P0002279 ! regulation of intermediate filament polymerization and/or depolymerization [Term] id: CCO:P0001336 name: negative regulation of intermediate filament depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intermediate filament depolymerization." [GOC:mah] comment: This term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament polymerization ; GO:0030840'). synonym: "down regulation of intermediate filament depolymerization" EXACT [] synonym: "down-regulation of intermediate filament depolymerization" EXACT [] synonym: "downregulation of intermediate filament depolymerization" EXACT [] synonym: "inhibition of intermediate filament depolymerization" NARROW [] synonym: "negative regulation of intermediate filament polymerization and/or depolymerization" BROAD [] xref: GO:0030843 is_a: CCO:P0001335 ! regulation of intermediate filament depolymerization is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001337 name: positive regulation of intermediate filament depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization." [GOC:mah] comment: This term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament polymerization ; GO:0030841'). synonym: "activation of intermediate filament depolymerization" NARROW [] synonym: "positive regulation of intermediate filament polymerization and/or depolymerization" BROAD [] synonym: "stimulation of intermediate filament depolymerization" NARROW [] synonym: "up regulation of intermediate filament depolymerization" EXACT [] synonym: "up-regulation of intermediate filament depolymerization" EXACT [] synonym: "upregulation of intermediate filament depolymerization" EXACT [] xref: GO:0030844 is_a: CCO:P0001335 ! regulation of intermediate filament depolymerization is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001338 name: inhibition of phospholipase C activity namespace: biological_process def: "A signaling pathway that results in preventing the activation of phospholipase C in response to the signal." [GOC:dph, GOC:mah, GOC:tb, PMID:8280098] comment: Note that this term refers to a signaling pathway, and should not be confused with function terms such as 'phospholipase inhibitor activity ; GO:0004859'. synonym: "phospholipase C inhibition" EXACT [GOC:dph, GOC:tb] xref: GO:0030845 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:P0001339 name: regulation of granulocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of granulocyte differentiation." [GOC:mah] xref: GO:0030852 is_a: CCO:P0000575 ! regulation of myeloid leukocyte differentiation [Term] id: CCO:P0001340 name: negative regulation of granulocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of granulocyte differentiation." [GOC:mah] synonym: "down regulation of granulocyte differentiation" EXACT [] synonym: "down-regulation of granulocyte differentiation" EXACT [] synonym: "downregulation of granulocyte differentiation" EXACT [] synonym: "inhibition of granulocyte differentiation" NARROW [] xref: GO:0030853 is_a: CCO:P0000576 ! negative regulation of myeloid leukocyte differentiation is_a: CCO:P0001339 ! regulation of granulocyte differentiation [Term] id: CCO:P0001341 name: positive regulation of granulocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of granulocyte differentiation." [GOC:mah] synonym: "activation of granulocyte differentiation" NARROW [] synonym: "stimulation of granulocyte differentiation" NARROW [] synonym: "up regulation of granulocyte differentiation" EXACT [] synonym: "up-regulation of granulocyte differentiation" EXACT [] synonym: "upregulation of granulocyte differentiation" EXACT [] xref: GO:0030854 is_a: CCO:P0000577 ! positive regulation of myeloid leukocyte differentiation is_a: CCO:P0001339 ! regulation of granulocyte differentiation relationship: has_participant CCO:B0033619 ! RUNX1_HUMAN [Term] id: CCO:P0001342 name: regulation of epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] xref: GO:0030856 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0001371 ! LX15B_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: has_participant CCO:B0055396 ! XDH_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN [Term] id: CCO:P0001343 name: negative regulation of epithelial cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "down regulation of epithelial cell differentiation" EXACT [] synonym: "down-regulation of epithelial cell differentiation" EXACT [] synonym: "downregulation of epithelial cell differentiation" EXACT [] synonym: "inhibition of epithelial cell differentiation" NARROW [] xref: GO:0030857 is_a: CCO:P0001342 ! regulation of epithelial cell differentiation is_a: CCO:P0002410 ! negative regulation of cell differentiation relationship: has_participant CCO:B0005456 ! CAV1_HUMAN [Term] id: CCO:P0001344 name: positive regulation of epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "activation of epithelial cell differentiation" NARROW [] synonym: "stimulation of epithelial cell differentiation" NARROW [] synonym: "up regulation of epithelial cell differentiation" EXACT [] synonym: "up-regulation of epithelial cell differentiation" EXACT [] synonym: "upregulation of epithelial cell differentiation" EXACT [] xref: GO:0030858 is_a: CCO:P0001342 ! regulation of epithelial cell differentiation is_a: CCO:P0002411 ! positive regulation of cell differentiation relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:P0001345 name: regulation of polarized epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation." [GOC:mah] xref: GO:0030860 is_a: CCO:P0001342 ! regulation of epithelial cell differentiation [Term] id: CCO:P0001346 name: negative regulation of polarized epithelial cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of polarized epithelial cell differentiation." [GOC:mah] synonym: "down regulation of polarized epithelial cell differentiation" EXACT [] synonym: "down-regulation of polarized epithelial cell differentiation" EXACT [] synonym: "downregulation of polarized epithelial cell differentiation" EXACT [] synonym: "inhibition of polarized epithelial cell differentiation" NARROW [] xref: GO:0030861 is_a: CCO:P0001343 ! negative regulation of epithelial cell differentiation is_a: CCO:P0001345 ! regulation of polarized epithelial cell differentiation [Term] id: CCO:P0001347 name: positive regulation of polarized epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the rate or extent of polarized epithelial cell differentiation." [GOC:mah] synonym: "activation of polarized epithelial cell differentiation" NARROW [] synonym: "stimulation of polarized epithelial cell differentiation" NARROW [] synonym: "up regulation of polarized epithelial cell differentiation" EXACT [] synonym: "up-regulation of polarized epithelial cell differentiation" EXACT [] synonym: "upregulation of polarized epithelial cell differentiation" EXACT [] xref: GO:0030862 is_a: CCO:P0001344 ! positive regulation of epithelial cell differentiation is_a: CCO:P0001345 ! regulation of polarized epithelial cell differentiation [Term] id: CCO:P0001348 name: regulation of myeloid dendritic cell activation namespace: biological_process def: "Any process that modulates the frequency or rate of myeloid dendritic cell activation." [GOC:mah] xref: GO:0030885 is_a: CCO:P0000562 ! regulation of leukocyte activation [Term] id: CCO:P0001349 name: negative regulation of myeloid dendritic cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell activation." [GOC:mah] synonym: "down regulation of myeloid dendritic cell activation" EXACT [] synonym: "down-regulation of myeloid dendritic cell activation" EXACT [] synonym: "downregulation of myeloid dendritic cell activation" EXACT [] synonym: "inhibition of myeloid dendritic cell activation" NARROW [] xref: GO:0030886 is_a: CCO:P0000563 ! negative regulation of leukocyte activation is_a: CCO:P0001348 ! regulation of myeloid dendritic cell activation relationship: has_participant CCO:B0055142 ! IL10_HUMAN [Term] id: CCO:P0001350 name: positive regulation of myeloid dendritic cell activation namespace: biological_process def: "Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation." [GOC:mah] synonym: "activation of myeloid dendritic cell activation" NARROW [] synonym: "stimulation of myeloid dendritic cell activation" NARROW [] synonym: "up regulation of myeloid dendritic cell activation" EXACT [] synonym: "up-regulation of myeloid dendritic cell activation" EXACT [] synonym: "upregulation of myeloid dendritic cell activation" EXACT [] xref: GO:0030887 is_a: CCO:P0000564 ! positive regulation of leukocyte activation is_a: CCO:P0001348 ! regulation of myeloid dendritic cell activation relationship: has_participant CCO:B0023521 ! CD2_HUMAN [Term] id: CCO:P0001351 name: regulation of B cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of B cell proliferation." [GOC:mah] synonym: "regulation of B lymphocyte proliferation" EXACT [] synonym: "regulation of B-cell proliferation" EXACT [] synonym: "regulation of B-lymphocyte proliferation" EXACT [] xref: GO:0030888 is_a: CCO:P0002914 ! regulation of lymphocyte proliferation is_a: CCO:P0002982 ! regulation of B cell activation relationship: regulates CCO:P0002040 ! B cell proliferation [Term] id: CCO:P0001352 name: negative regulation of B cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of B cell proliferation." [GOC:mah] synonym: "down regulation of B cell proliferation" EXACT [] synonym: "down-regulation of B cell proliferation" EXACT [] synonym: "downregulation of B cell proliferation" EXACT [] synonym: "inhibition of B cell proliferation" NARROW [] synonym: "negative regulation of B lymphocyte proliferation" EXACT [] synonym: "negative regulation of B-cell proliferation" EXACT [] synonym: "negative regulation of B-lymphocyte proliferation" EXACT [] xref: GO:0030889 is_a: CCO:P0001351 ! regulation of B cell proliferation is_a: CCO:P0002916 ! negative regulation of lymphocyte proliferation is_a: CCO:P0002987 ! negative regulation of B cell activation relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0039914 ! TR13B_HUMAN relationship: negatively_regulates CCO:P0002040 ! B cell proliferation [Term] id: CCO:P0001353 name: positive regulation of B cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of B cell proliferation." [GOC:mah] synonym: "activation of B cell proliferation" NARROW [] synonym: "positive regulation of B lymphocyte proliferation" EXACT [] synonym: "positive regulation of B-cell proliferation" EXACT [] synonym: "positive regulation of B-lymphocyte proliferation" EXACT [] synonym: "stimulation of B cell proliferation" NARROW [] synonym: "up regulation of B cell proliferation" EXACT [] synonym: "up-regulation of B cell proliferation" EXACT [] synonym: "upregulation of B cell proliferation" EXACT [] xref: GO:0030890 is_a: CCO:P0001351 ! regulation of B cell proliferation is_a: CCO:P0002915 ! positive regulation of lymphocyte proliferation is_a: CCO:P0002989 ! positive regulation of B cell activation relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN relationship: has_participant CCO:B0049019 ! IGHM_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN relationship: positively_regulates CCO:P0002040 ! B cell proliferation [Term] id: CCO:P0001354 name: regulation of vascular endothelial growth factor receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity." [GOC:dgh] synonym: "regulation of vascular endothelial growth factor receptor signalling pathway" EXACT [] synonym: "regulation of VEGF receptor signaling pathway" EXACT [] synonym: "regulation of VEGF receptor signalling pathway" EXACT [] xref: GO:0030947 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:P0001355 name: negative regulation of vascular endothelial growth factor receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity." [GOC:dgh] synonym: "down regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] synonym: "down-regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] synonym: "downregulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] synonym: "inhibition of vascular endothelial growth factor receptor signaling pathway" NARROW [] synonym: "negative regulation of vascular endothelial growth factor receptor signalling pathway" EXACT [] synonym: "negative regulation of VEGF receptor signaling pathway" EXACT [] synonym: "negative regulation of VEGF receptor signalling pathway" EXACT [] xref: GO:0030948 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001354 ! regulation of vascular endothelial growth factor receptor signaling pathway relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: has_participant CCO:B0054672 ! LECT1_HUMAN relationship: negatively_regulates CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:P0001356 name: positive regulation of vascular endothelial growth factor receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity." [GOC:dgh] synonym: "activation of vascular endothelial growth factor receptor signaling pathway" NARROW [] synonym: "positive regulation of vascular endothelial growth factor receptor signalling pathway" EXACT [] synonym: "positive regulation of VEGF receptor signaling pathway" EXACT [] synonym: "positive regulation of VEGF receptor signalling pathway" EXACT [] synonym: "stimulation of vascular endothelial growth factor receptor signaling pathway" NARROW [] synonym: "up regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] synonym: "up-regulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] synonym: "upregulation of vascular endothelial growth factor receptor signaling pathway" EXACT [] xref: GO:0030949 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001354 ! regulation of vascular endothelial growth factor receptor signaling pathway relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0022986 ! FGF18_HUMAN relationship: positively_regulates CCO:P0002756 ! vascular endothelial growth factor receptor signaling pathway [Term] id: CCO:P0001357 name: ER-nuclear sterol response pathway namespace: biological_process def: "The series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of sterol depletion, and resulting in the activation of transcription by SREBP." [GOC:mah, PMID:12923525] synonym: "endoplasmic reticulum to nucleus sterol response pathway" EXACT [] synonym: "endoplasmic reticulum-nuclear sterol response pathway" EXACT [] synonym: "ER to nucleus sterol response pathway" EXACT [] xref: GO:0030967 is_a: CCO:P0001721 ! SREBP-mediated signaling pathway [Term] id: CCO:P0001358 name: endoplasmic reticulum unfolded protein response namespace: biological_process def: "The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation." [GOC:mah, PMID:12042763] comment: Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any cellular response to the presence of unfolded proteins anywhere in the cell. Also see 'ER-associated protein catabolic process ; GO:0030433'. synonym: "ER stress response" BROAD [] synonym: "ER unfolded protein response" EXACT [] synonym: "erUPR" EXACT [] synonym: "SREBP-mediated signalling pathway" RELATED [] xref: GO:0030968 is_a: CCO:P0000685 ! ER-nuclear signaling pathway relationship: has_participant CCO:B0001535 ! E2AK2_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0054746 ! VAPB_HUMAN relationship: has_participant CCO:B0058351 ! DERL3_HUMAN relationship: has_participant CCO:B0058480 ! SELS_HUMAN relationship: has_participant CCO:B0058523 ! DERL1_HUMAN relationship: has_participant CCO:B0058631 ! DERL2_HUMAN relationship: has_participant CCO:B0059206 ! AMFR2_HUMAN [Term] id: CCO:P0001359 name: UFP-specific transcription factor mRNA processing during unfolded protein response namespace: biological_process def: "The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes." [GOC:mah, PMID:12042763] synonym: "unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor" RELATED [] synonym: "unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase" RELATED [] xref: GO:0030969 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001358 ! endoplasmic reticulum unfolded protein response [Term] id: CCO:P0001360 name: cleavage of cytosolic proteins during apoptosis namespace: biological_process def: "The proteolytic degradation of proteins in the cytosol during apoptosis." [GOC:mah, ISBN:0815332181] synonym: "apoptotic cleavage of cytosolic proteins" EXACT [] xref: GO:0030972 is_a: CCO:P0000674 ! cell structure disassembly during apoptosis [Term] id: CCO:P0001361 name: primary cell septum disassembly namespace: biological_process def: "Dissolution of the primary septum during cell separation." [PMID:12665550] synonym: "hydrolysis of primary cell septum" EXACT [] synonym: "primary cell septum hydrolysis" EXACT [] synonym: "primary septum hydrolysis" BROAD [] xref: GO:0030994 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000456 ! cell separation during cytokinesis [Term] id: CCO:P0001362 name: cell septum edging catabolic process namespace: biological_process def: "Dissolution of the septum edging during cell separation." [PMID:15194814] synonym: "cell septum edging hydrolysis" EXACT [] synonym: "hydrolysis of cell septum edging" EXACT [] synonym: "hydrolysis of edging of cell septum" EXACT [] synonym: "septum edging hydrolysis" BROAD [] xref: GO:0030995 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000456 ! cell separation during cytokinesis [Term] id: CCO:P0001363 name: gene silencing by RNA namespace: biological_process def: "Any process by which RNA molecules inactivate expression of target genes." [GOC:dph, GOC:mah, GOC:tb, PMID:15020054] synonym: "RNA-mediated gene silencing" EXACT [GOC:dph, GOC:tb] xref: GO:0031047 is_a: CCO:P0001125 ! gene silencing relationship: has_participant CCO:B0006026 ! RNC_HUMAN relationship: has_participant CCO:B0016049 ! I2C2_HUMAN relationship: has_participant CCO:B0016054 ! I2C3_HUMAN relationship: has_participant CCO:B0016055 ! I2C4_HUMAN relationship: has_participant CCO:B0016057 ! I2C1_HUMAN relationship: has_participant CCO:B0019369 ! PIWL1_HUMAN relationship: has_participant CCO:B0037436 ! XPO5_HUMAN relationship: has_participant CCO:B0055532 ! DSRAD_HUMAN relationship: has_participant CCO:B0057336 ! THEX1_HUMAN [Term] id: CCO:P0001364 name: chromatin silencing by small RNA namespace: biological_process def: "Repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region." [GOC:dph, GOC:mtg_lung, GOC:ns] synonym: "RNA interference-like chromatin silencing" EXACT [] synonym: "RNA-mediated chromatin silencing" EXACT [GOC:dph, GOC:tb] synonym: "RNA-mediated TGS" BROAD [] synonym: "RNA-mediated transcriptional silencing" EXACT [] synonym: "RNAi-like chromatin silencing" EXACT [] synonym: "small RNA-mediated heterochromatic silencing" EXACT [] synonym: "small RNA-mediated heterochromatin biosynthesis" EXACT [] synonym: "small RNA-mediated heterochromatin formation" EXACT [] xref: GO:0031048 is_a: CCO:P0000648 ! chromatin silencing is_a: CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:P0001365 name: primary microRNA processing namespace: biological_process def: "Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule." [PMID:15211354] synonym: "pri-miRNA processing" EXACT [] synonym: "primary miRNA processing" EXACT [] xref: GO:0031053 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0058048 ! DGCR8_HUMAN relationship: part_of CCO:P0002004 ! gene silencing by miRNA, production of miRNAs [Term] id: CCO:P0001366 name: pre-microRNA processing namespace: biological_process def: "Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule." [PMID:15211354] synonym: "pre-miRNA processing" EXACT [] xref: GO:0031054 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002004 ! gene silencing by miRNA, production of miRNAs [Term] id: CCO:P0001367 name: regulation of histone modification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the covalent alteration of a histone." [GOC:mah] xref: GO:0031056 is_a: CCO:P0001433 ! regulation of protein modification process is_a: CCO:P0001766 ! regulation of chromosome organization and biogenesis [Term] id: CCO:P0001368 name: negative regulation of histone modification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the covalent alteration of a histone." [GOC:mah] synonym: "down regulation of histone modification" EXACT [] synonym: "down-regulation of histone modification" EXACT [] synonym: "downregulation of histone modification" EXACT [] synonym: "inhibition of histone modification" NARROW [] xref: GO:0031057 is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis is_a: CCO:P0001367 ! regulation of histone modification is_a: CCO:P0001434 ! negative regulation of protein modification process [Term] id: CCO:P0001369 name: positive regulation of histone modification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone." [GOC:mah] synonym: "activation of histone modification" NARROW [] synonym: "stimulation of histone modification" NARROW [] synonym: "up regulation of histone modification" EXACT [] synonym: "up-regulation of histone modification" EXACT [] synonym: "upregulation of histone modification" EXACT [] xref: GO:0031058 is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis is_a: CCO:P0001367 ! regulation of histone modification is_a: CCO:P0001435 ! positive regulation of protein modification process relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN [Term] id: CCO:P0001370 name: regulation of histone methylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones." [GOC:mah] xref: GO:0031060 is_a: CCO:P0001367 ! regulation of histone modification [Term] id: CCO:P0001371 name: negative regulation of histone methylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones." [GOC:mah] synonym: "down regulation of histone methylation" EXACT [] synonym: "down-regulation of histone methylation" EXACT [] synonym: "downregulation of histone methylation" EXACT [] synonym: "inhibition of histone methylation" NARROW [] xref: GO:0031061 is_a: CCO:P0001368 ! negative regulation of histone modification is_a: CCO:P0001370 ! regulation of histone methylation [Term] id: CCO:P0001372 name: positive regulation of histone methylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones." [GOC:mah] synonym: "activation of histone methylation" NARROW [] synonym: "stimulation of histone methylation" NARROW [] synonym: "up regulation of histone methylation" EXACT [] synonym: "up-regulation of histone methylation" EXACT [] synonym: "upregulation of histone methylation" EXACT [] xref: GO:0031062 is_a: CCO:P0001369 ! positive regulation of histone modification is_a: CCO:P0001370 ! regulation of histone methylation [Term] id: CCO:P0001373 name: regulation of histone deacetylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones." [GOC:mah] xref: GO:0031063 is_a: CCO:P0001367 ! regulation of histone modification [Term] id: CCO:P0001374 name: negative regulation of histone deacetylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the removal of acetyl groups from histones." [GOC:mah] synonym: "down regulation of histone deacetylation" EXACT [] synonym: "down-regulation of histone deacetylation" EXACT [] synonym: "downregulation of histone deacetylation" EXACT [] synonym: "inhibition of histone deacetylation" NARROW [] xref: GO:0031064 is_a: CCO:P0001368 ! negative regulation of histone modification is_a: CCO:P0001373 ! regulation of histone deacetylation [Term] id: CCO:P0001375 name: positive regulation of histone deacetylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones." [GOC:mah] synonym: "activation of histone deacetylation" NARROW [] synonym: "stimulation of histone deacetylation" NARROW [] synonym: "up regulation of histone deacetylation" EXACT [] synonym: "up-regulation of histone deacetylation" EXACT [] synonym: "upregulation of histone deacetylation" EXACT [] xref: GO:0031065 is_a: CCO:P0001369 ! positive regulation of histone modification is_a: CCO:P0001373 ! regulation of histone deacetylation [Term] id: CCO:P0001376 name: regulation of histone deacetylation at centromere namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA." [GOC:mah] xref: GO:0031066 is_a: CCO:P0001373 ! regulation of histone deacetylation [Term] id: CCO:P0001377 name: negative regulation of histone deacetylation at centromere namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA." [GOC:mah] synonym: "down regulation of histone deacetylation at centromere" EXACT [] synonym: "down-regulation of histone deacetylation at centromere" EXACT [] synonym: "downregulation of histone deacetylation at centromere" EXACT [] synonym: "inhibition of histone deacetylation at centromere" NARROW [] xref: GO:0031067 is_a: CCO:P0001374 ! negative regulation of histone deacetylation is_a: CCO:P0001376 ! regulation of histone deacetylation at centromere [Term] id: CCO:P0001378 name: positive regulation of histone deacetylation at centromere namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA." [GOC:mah] synonym: "activation of histone deacetylation at centromere" NARROW [] synonym: "stimulation of histone deacetylation at centromere" NARROW [] synonym: "up regulation of histone deacetylation at centromere" EXACT [] synonym: "up-regulation of histone deacetylation at centromere" EXACT [] synonym: "upregulation of histone deacetylation at centromere" EXACT [] xref: GO:0031068 is_a: CCO:P0001375 ! positive regulation of histone deacetylation is_a: CCO:P0001376 ! regulation of histone deacetylation at centromere [Term] id: CCO:P0001379 name: stress-activated protein kinase signaling pathway namespace: biological_process def: "A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals." [GOC:mah] synonym: "JNK signaling pathway" NARROW [] synonym: "JNK signalling pathway" NARROW [] synonym: "SAPK signaling pathway" EXACT [] synonym: "SAPK signalling pathway" EXACT [] synonym: "stress-activated protein kinase signalling pathway" EXACT [] xref: GO:0031098 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0056955 ! GFRAL_HUMAN [Term] id: CCO:P0001380 name: regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] xref: GO:0031110 is_a: CCO:P0001703 ! regulation of microtubule-based process relationship: has_participant CCO:B0001422 ! CLAP2_HUMAN [Term] id: CCO:P0001381 name: negative regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "down-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "downregulation of microtubule polymerization or depolymerization" EXACT [] synonym: "inhibition of microtubule polymerization or depolymerization" NARROW [] xref: GO:0031111 is_a: CCO:P0001380 ! regulation of microtubule polymerization or depolymerization is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis relationship: has_participant CCO:B0001933 ! CLAP1_HUMAN [Term] id: CCO:P0001382 name: positive regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "activation of microtubule polymerization or depolymerization" NARROW [] synonym: "stimulation of microtubule polymerization or depolymerization" NARROW [] synonym: "up regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "up-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "upregulation of microtubule polymerization or depolymerization" EXACT [] xref: GO:0031112 is_a: CCO:P0001380 ! regulation of microtubule polymerization or depolymerization is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001383 name: regulation of microtubule polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization." [GOC:mah] xref: GO:0031113 is_a: CCO:P0001380 ! regulation of microtubule polymerization or depolymerization is_a: CCO:P0001575 ! regulation of protein polymerization relationship: has_participant CCO:B0054976 ! TAU_HUMAN [Term] id: CCO:P0001384 name: regulation of microtubule depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "regulation of microtubule disassembly" EXACT [] xref: GO:0031114 is_a: CCO:P0001380 ! regulation of microtubule polymerization or depolymerization is_a: CCO:P0001572 ! regulation of cellular protein metabolic process [Term] id: CCO:P0001385 name: negative regulation of microtubule polymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization" EXACT [] synonym: "down-regulation of microtubule polymerization" EXACT [] synonym: "downregulation of microtubule polymerization" EXACT [] synonym: "inhibition of microtubule polymerization" NARROW [] xref: GO:0031115 is_a: CCO:P0001381 ! negative regulation of microtubule polymerization or depolymerization is_a: CCO:P0001383 ! regulation of microtubule polymerization is_a: CCO:P0001576 ! negative regulation of protein polymerization relationship: has_participant CCO:B0001812 ! MARE1_HUMAN [Term] id: CCO:P0001386 name: positive regulation of microtubule polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "activation of microtubule polymerization" NARROW [] synonym: "stimulation of microtubule polymerization" NARROW [] synonym: "up regulation of microtubule polymerization" EXACT [] synonym: "up-regulation of microtubule polymerization" EXACT [] synonym: "upregulation of microtubule polymerization" EXACT [] xref: GO:0031116 is_a: CCO:P0001382 ! positive regulation of microtubule polymerization or depolymerization is_a: CCO:P0001383 ! regulation of microtubule polymerization is_a: CCO:P0001577 ! positive regulation of protein polymerization relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005462 ! CAV2_HUMAN relationship: has_participant CCO:B0005605 ! CFTR_HUMAN relationship: has_participant CCO:B0043829 ! PSRC1_HUMAN relationship: has_participant CCO:B0054945 ! WNT2_HUMAN relationship: has_participant CCO:B0054976 ! TAU_HUMAN relationship: has_participant CCO:B0058004 ! ASZ1_HUMAN relationship: has_participant CCO:B0058050 ! CTTB2_HUMAN [Term] id: CCO:P0001387 name: positive regulation of microtubule depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "activation of microtubule depolymerization" NARROW [] synonym: "microtubule destabilization" EXACT [] synonym: "positive regulation of microtubule disassembly" EXACT [] synonym: "stimulation of microtubule depolymerization" NARROW [] synonym: "up regulation of microtubule depolymerization" EXACT [] synonym: "up-regulation of microtubule depolymerization" EXACT [] synonym: "upregulation of microtubule depolymerization" EXACT [] xref: GO:0031117 is_a: CCO:P0001382 ! positive regulation of microtubule polymerization or depolymerization is_a: CCO:P0001384 ! regulation of microtubule depolymerization is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process relationship: has_participant CCO:B0002100 ! KTNB1_HUMAN [Term] id: CCO:P0001388 name: regulation of axon diameter namespace: biological_process def: "Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained." [GOC:dph, GOC:mah, GOC:tb] xref: GO:0031133 is_a: CCO:P0002948 ! regulation of axonogenesis relationship: has_participant CCO:B0054341 ! WNT7A_HUMAN relationship: has_participant CCO:B0054909 ! NFM_HUMAN [Term] id: CCO:P0001389 name: regulation of pseudopodium formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg] xref: GO:0031272 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis [Term] id: CCO:P0001390 name: negative regulation of pseudopodium formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg] synonym: "down regulation of pseudopodium formation" EXACT [] synonym: "down-regulation of pseudopodium formation" EXACT [] synonym: "downregulation of pseudopodium formation" EXACT [] synonym: "inhibition of pseudopodium formation" NARROW [] xref: GO:0031273 is_a: CCO:P0001389 ! regulation of pseudopodium formation is_a: CCO:P0001422 ! negative regulation of cell projection organization and biogenesis [Term] id: CCO:P0001391 name: positive regulation of pseudopodium formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia." [GOC:pg] synonym: "activation of pseudopodium formation" NARROW [] synonym: "stimulation of pseudopodium formation" NARROW [] synonym: "up regulation of pseudopodium formation" EXACT [] synonym: "up-regulation of pseudopodium formation" EXACT [] synonym: "upregulation of pseudopodium formation" EXACT [] xref: GO:0031274 is_a: CCO:P0001389 ! regulation of pseudopodium formation is_a: CCO:P0001423 ! positive regulation of cell projection organization and biogenesis relationship: has_participant CCO:B0005338 ! CDC42_HUMAN relationship: has_participant CCO:B0054357 ! BORG1_HUMAN relationship: has_participant CCO:B0055680 ! BORG5_HUMAN relationship: has_participant CCO:B0056874 ! BORG3_HUMAN relationship: has_participant CCO:B0058708 ! BORG4_HUMAN [Term] id: CCO:P0001392 name: regulation of lateral pseudopodium formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:pg] xref: GO:0031275 is_a: CCO:P0001389 ! regulation of pseudopodium formation [Term] id: CCO:P0001393 name: negative regulation of lateral pseudopodium formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:pg] synonym: "down regulation of lateral pseudopodium formation" EXACT [] synonym: "down-regulation of lateral pseudopodium formation" EXACT [] synonym: "downregulation of lateral pseudopodium formation" EXACT [] synonym: "inhibition of lateral pseudopodium formation" NARROW [] xref: GO:0031276 is_a: CCO:P0001390 ! negative regulation of pseudopodium formation is_a: CCO:P0001392 ! regulation of lateral pseudopodium formation [Term] id: CCO:P0001394 name: positive regulation of lateral pseudopodium formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell." [GOC:pg] synonym: "activation of lateral pseudopodium formation" NARROW [] synonym: "stimulation of lateral pseudopodium formation" NARROW [] synonym: "up regulation of lateral pseudopodium formation" EXACT [] synonym: "up-regulation of lateral pseudopodium formation" EXACT [] synonym: "upregulation of lateral pseudopodium formation" EXACT [] xref: GO:0031277 is_a: CCO:P0001391 ! positive regulation of pseudopodium formation is_a: CCO:P0001392 ! regulation of lateral pseudopodium formation [Term] id: CCO:P0001395 name: regulation of sorocarp stalk cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation." [DDB_REF:5048 "DictyBase paper repository", GOC:kp, GOC:mtg_sensu] synonym: "regulation of stalk cell differentiation" EXACT [] xref: GO:0031285 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0001396 name: negative regulation of sorocarp stalk cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp stalk cell differentiation." [DDB_REF:5048 "DictyBase paper repository", GOC:kp, GOC:mtg_sensu] synonym: "down regulation of stalk cell differentiation" EXACT [] synonym: "down-regulation of stalk cell differentiation" EXACT [] synonym: "downregulation of stalk cell differentiation" EXACT [] synonym: "inhibition of stalk cell differentiation" NARROW [] synonym: "negative regulation of stalk cell differentiation" EXACT [] xref: GO:0031286 is_a: CCO:P0001395 ! regulation of sorocarp stalk cell differentiation is_a: CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:P0001397 name: positive regulation of sorocarp stalk cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation." [DDB_REF:5048 "DictyBase paper repository", GOC:kp, GOC:mtg_sensu] synonym: "activation of stalk cell differentiation" NARROW [] synonym: "positive regulation of stalk cell differentiation" EXACT [] synonym: "stimulation of stalk cell differentiation" NARROW [] synonym: "up regulation of stalk cell differentiation" EXACT [] synonym: "up-regulation of stalk cell differentiation" EXACT [] synonym: "upregulation of stalk cell differentiation" EXACT [] xref: GO:0031287 is_a: CCO:P0001395 ! regulation of sorocarp stalk cell differentiation is_a: CCO:P0002411 ! positive regulation of cell differentiation [Term] id: CCO:P0001398 name: Ran protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state." [GOC:mah] xref: GO:0031291 is_a: CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:P0001399 name: gene conversion at mating-type locus, DNA double-strand break processing namespace: biological_process def: "The 5' to 3' exonucleolytic resection of the DNA at the site of the break at the mating-type locus to form a 3' single-strand DNA overhang." [GOC:mah] xref: GO:0031292 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000799 ! gene conversion at mating-type locus [Term] id: CCO:P0001400 name: lymphocyte costimulation namespace: biological_process def: "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "lymphocyte co-stimulation" EXACT [] xref: GO:0031294 is_a: CCO:P0003067 ! positive regulation of lymphocyte activation [Term] id: CCO:P0001401 name: T cell costimulation namespace: biological_process def: "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "T cell co-stimulation" EXACT [] synonym: "T lymphocyte costimulation" EXACT [] synonym: "T-cell co-stimulation" EXACT [] synonym: "T-cell costimulation" EXACT [] synonym: "T-lymphocyte costimulation" EXACT [] xref: GO:0031295 is_a: CCO:P0001400 ! lymphocyte costimulation is_a: CCO:P0002988 ! positive regulation of T cell activation relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0054901 ! CD5_HUMAN relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:P0001402 name: B cell costimulation namespace: biological_process def: "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "B cell co-stimulation " EXACT [] synonym: "B lymphocyte co-stimulation" EXACT [] synonym: "B lymphocyte costimulation" EXACT [] synonym: "B-cell co-stimulation" EXACT [] synonym: "B-cell costimulation" EXACT [] synonym: "B-lymphocyte co-stimulation" EXACT [] synonym: "B-lymphocyte costimulation" EXACT [] xref: GO:0031296 is_a: CCO:P0001400 ! lymphocyte costimulation is_a: CCO:P0002989 ! positive regulation of B cell activation relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:P0001403 name: ascospore-type prospore formation namespace: biological_process def: "During ascospore formation, the process by which each haploid nucleus becomes encapsulated by a double membrane." [GOC:mah, PMID:14702385] synonym: "forespore formation (sensu Fungi)" EXACT [] xref: GO:0031321 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001262 ! ascospore formation [Term] id: CCO:P0001404 name: regulation of cellular metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gosubset_prok synonym: "regulation of cellular metabolism" EXACT [] xref: GO:0031323 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0054915 ! HEXB_HUMAN [Term] id: CCO:P0001405 name: negative regulation of cellular metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cellular metabolic process" EXACT [] synonym: "down-regulation of cellular metabolic process" EXACT [] synonym: "downregulation of cellular metabolic process" EXACT [] synonym: "inhibition of cellular metabolic process" NARROW [] synonym: "negative regulation of cellular metabolism" EXACT [] xref: GO:0031324 is_a: CCO:P0001404 ! regulation of cellular metabolic process is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0001406 name: positive regulation of cellular metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gosubset_prok synonym: "activation of cellular metabolic process" NARROW [] synonym: "positive regulation of cellular metabolism" EXACT [] synonym: "stimulation of cellular metabolic process" NARROW [] synonym: "up regulation of cellular metabolic process" EXACT [] synonym: "up-regulation of cellular metabolic process" EXACT [] synonym: "upregulation of cellular metabolic process" EXACT [] xref: GO:0031325 is_a: CCO:P0001404 ! regulation of cellular metabolic process is_a: CCO:P0002852 ! positive regulation of cellular process [Term] id: CCO:P0001407 name: regulation of cellular biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] subset: gosubset_prok synonym: "regulation of cellular anabolism" EXACT [] synonym: "regulation of cellular biosynthesis" EXACT [] synonym: "regulation of cellular formation" EXACT [] synonym: "regulation of cellular synthesis" EXACT [] xref: GO:0031326 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001408 name: negative regulation of cellular biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cellular biosynthetic process" EXACT [] synonym: "down-regulation of cellular biosynthetic process" EXACT [] synonym: "downregulation of cellular biosynthetic process" EXACT [] synonym: "inhibition of cellular biosynthetic process" NARROW [] synonym: "negative regulation of cellular anabolism" EXACT [] synonym: "negative regulation of cellular biosynthesis" EXACT [] synonym: "negative regulation of cellular formation" EXACT [] synonym: "negative regulation of cellular synthesis" EXACT [] xref: GO:0031327 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0001409 name: positive regulation of cellular biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] subset: gosubset_prok synonym: "activation of cellular biosynthetic process" NARROW [] synonym: "positive regulation of cellular anabolism" EXACT [] synonym: "positive regulation of cellular biosynthesis" EXACT [] synonym: "positive regulation of cellular formation" EXACT [] synonym: "positive regulation of cellular synthesis" EXACT [] synonym: "stimulation of cellular biosynthetic process" NARROW [] synonym: "up regulation of cellular biosynthetic process" EXACT [] synonym: "up-regulation of cellular biosynthetic process" EXACT [] synonym: "upregulation of cellular biosynthetic process" EXACT [] xref: GO:0031328 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0001410 name: regulation of cellular catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] subset: gosubset_prok synonym: "regulation of cellular breakdown" EXACT [] synonym: "regulation of cellular catabolism" EXACT [] synonym: "regulation of cellular degradation" EXACT [] xref: GO:0031329 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001411 name: negative regulation of cellular catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] subset: gosubset_prok synonym: "down regulation of cellular catabolic process" EXACT [] synonym: "down-regulation of cellular catabolic process" EXACT [] synonym: "downregulation of cellular catabolic process" EXACT [] synonym: "inhibition of cellular catabolic process" NARROW [] synonym: "negative regulation of cellular breakdown" EXACT [] synonym: "negative regulation of cellular catabolism" EXACT [] synonym: "negative regulation of cellular degradation" EXACT [] xref: GO:0031330 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0001412 name: positive regulation of cellular catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] subset: gosubset_prok synonym: "activation of cellular catabolic process" NARROW [] synonym: "positive regulation of cellular breakdown" EXACT [] synonym: "positive regulation of cellular catabolism" EXACT [] synonym: "positive regulation of cellular degradation" EXACT [] synonym: "stimulation of cellular catabolic process" NARROW [] synonym: "up regulation of cellular catabolic process" EXACT [] synonym: "up-regulation of cellular catabolic process" EXACT [] synonym: "upregulation of cellular catabolic process" EXACT [] xref: GO:0031331 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0001413 name: negative regulation of protein complex assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah] subset: gosubset_prok synonym: "down regulation of protein complex assembly" EXACT [] synonym: "down-regulation of protein complex assembly" EXACT [] synonym: "downregulation of protein complex assembly" EXACT [] synonym: "inhibition of protein complex assembly" NARROW [] xref: GO:0031333 is_a: CCO:P0002176 ! regulation of protein complex assembly is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0005338 ! CDC42_HUMAN [Term] id: CCO:P0001414 name: positive regulation of protein complex assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah] subset: gosubset_prok synonym: "activation of protein complex assembly" NARROW [] synonym: "stimulation of protein complex assembly" NARROW [] synonym: "up regulation of protein complex assembly" EXACT [] synonym: "up-regulation of protein complex assembly" EXACT [] synonym: "upregulation of protein complex assembly" EXACT [] xref: GO:0031334 is_a: CCO:P0002176 ! regulation of protein complex assembly is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0054357 ! BORG1_HUMAN relationship: has_participant CCO:B0054701 ! TPPP_HUMAN relationship: has_participant CCO:B0059254 ! FAF1_HUMAN [Term] id: CCO:P0001415 name: regulation of sulfur amino acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah] subset: gosubset_prok synonym: "regulation of sulfur amino acid metabolism" EXACT [] xref: GO:0031335 is_a: CCO:P0000668 ! regulation of amino acid metabolic process is_a: CCO:P0002124 ! regulation of sulfur metabolic process [Term] id: CCO:P0001416 name: negative regulation of sulfur amino acid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah] subset: gosubset_prok synonym: "down regulation of sulfur amino acid metabolic process" EXACT [] synonym: "down-regulation of sulfur amino acid metabolic process" EXACT [] synonym: "downregulation of sulfur amino acid metabolic process" EXACT [] synonym: "inhibition of sulfur amino acid metabolic process" NARROW [] synonym: "negative regulation of sulfur amino acid metabolism" EXACT [] xref: GO:0031336 is_a: CCO:P0001415 ! regulation of sulfur amino acid metabolic process is_a: CCO:P0002542 ! negative regulation of amino acid metabolic process is_a: CCO:P0003054 ! negative regulation of sulfur metabolic process [Term] id: CCO:P0001417 name: positive regulation of sulfur amino acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids." [GOC:mah] subset: gosubset_prok synonym: "activation of sulfur amino acid metabolic process" NARROW [] synonym: "positive regulation of sulfur amino acid metabolism" EXACT [] synonym: "stimulation of sulfur amino acid metabolic process" NARROW [] synonym: "up regulation of sulfur amino acid metabolic process" EXACT [] synonym: "up-regulation of sulfur amino acid metabolic process" EXACT [] synonym: "upregulation of sulfur amino acid metabolic process" EXACT [] xref: GO:0031337 is_a: CCO:P0001415 ! regulation of sulfur amino acid metabolic process is_a: CCO:P0002543 ! positive regulation of amino acid metabolic process is_a: CCO:P0003055 ! positive regulation of sulfur metabolic process [Term] id: CCO:P0001418 name: regulation of vesicle fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle fusion." [GOC:mah] xref: GO:0031338 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0001419 name: negative regulation of vesicle fusion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "down regulation of vesicle fusion" EXACT [] synonym: "down-regulation of vesicle fusion" EXACT [] synonym: "downregulation of vesicle fusion" EXACT [] synonym: "inhibition of vesicle fusion" NARROW [] xref: GO:0031339 is_a: CCO:P0001418 ! regulation of vesicle fusion is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis [Term] id: CCO:P0001420 name: positive regulation of vesicle fusion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "activation of vesicle fusion" NARROW [] synonym: "stimulation of vesicle fusion" NARROW [] synonym: "up regulation of vesicle fusion" EXACT [] synonym: "up-regulation of vesicle fusion" EXACT [] synonym: "upregulation of vesicle fusion" EXACT [] xref: GO:0031340 is_a: CCO:P0001418 ! regulation of vesicle fusion is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis [Term] id: CCO:P0001421 name: regulation of cell projection organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] subset: gosubset_prok synonym: "regulation of cell projection organisation and biogenesis" EXACT [] xref: GO:0031344 is_a: CCO:P0001241 ! regulation of cell morphogenesis [Term] id: CCO:P0001422 name: negative regulation of cell projection organization and biogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "down regulation of cell projection organization and biogenesis" EXACT [] synonym: "down-regulation of cell projection organization and biogenesis" EXACT [] synonym: "downregulation of cell projection organization and biogenesis" EXACT [] synonym: "inhibition of cell projection organization and biogenesis" NARROW [] synonym: "negative regulation of cell projection organisation and biogenesis" EXACT [] xref: GO:0031345 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis [Term] id: CCO:P0001423 name: positive regulation of cell projection organization and biogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "activation of cell projection organization and biogenesis" NARROW [] synonym: "positive regulation of cell projection organisation and biogenesis" EXACT [] synonym: "stimulation of cell projection organization and biogenesis" NARROW [] synonym: "up regulation of cell projection organization and biogenesis" EXACT [] synonym: "up-regulation of cell projection organization and biogenesis" EXACT [] synonym: "upregulation of cell projection organization and biogenesis" EXACT [] xref: GO:0031346 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis [Term] id: CCO:P0001424 name: regulation of mating projection biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi." [PMID:14734532] xref: GO:0031383 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis [Term] id: CCO:P0001425 name: regulation of initiation of mating projection growth namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi." [PMID:14734532] xref: GO:0031384 is_a: CCO:P0001424 ! regulation of mating projection biogenesis [Term] id: CCO:P0001426 name: regulation of termination of mating projection growth namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi." [PMID:14734532] xref: GO:0031385 is_a: CCO:P0001424 ! regulation of mating projection biogenesis [Term] id: CCO:P0001427 name: regulation of prostaglandin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah] synonym: "regulation of prostaglandin anabolism" EXACT [] synonym: "regulation of prostaglandin biosynthesis" EXACT [] synonym: "regulation of prostaglandin formation" EXACT [] synonym: "regulation of prostaglandin synthesis" EXACT [] xref: GO:0031392 is_a: CCO:P0002055 ! regulation of fatty acid biosynthetic process [Term] id: CCO:P0001428 name: negative regulation of prostaglandin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah] synonym: "down regulation of prostaglandin biosynthetic process" EXACT [] synonym: "down-regulation of prostaglandin biosynthetic process" EXACT [] synonym: "downregulation of prostaglandin biosynthetic process" EXACT [] synonym: "inhibition of prostaglandin biosynthetic process" NARROW [] synonym: "negative regulation of prostaglandin anabolism" EXACT [] synonym: "negative regulation of prostaglandin biosynthesis" EXACT [] synonym: "negative regulation of prostaglandin formation" EXACT [] synonym: "negative regulation of prostaglandin synthesis" EXACT [] xref: GO:0031393 is_a: CCO:P0001427 ! regulation of prostaglandin biosynthetic process is_a: CCO:P0002514 ! negative regulation of fatty acid biosynthetic process [Term] id: CCO:P0001429 name: positive regulation of prostaglandin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin." [GOC:mah] synonym: "activation of prostaglandin biosynthetic process" NARROW [] synonym: "positive regulation of prostaglandin anabolism" EXACT [] synonym: "positive regulation of prostaglandin biosynthesis" EXACT [] synonym: "positive regulation of prostaglandin formation" EXACT [] synonym: "positive regulation of prostaglandin synthesis" EXACT [] synonym: "stimulation of prostaglandin biosynthetic process" NARROW [] synonym: "up regulation of prostaglandin biosynthetic process" EXACT [] synonym: "up-regulation of prostaglandin biosynthetic process" EXACT [] synonym: "upregulation of prostaglandin biosynthetic process" EXACT [] xref: GO:0031394 is_a: CCO:P0001427 ! regulation of prostaglandin biosynthetic process is_a: CCO:P0002520 ! positive regulation of fatty acid biosynthetic process [Term] id: CCO:P0001430 name: regulation of protein ubiquitination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the addition of ubiquitin moieties to a protein." [GOC:mah] xref: GO:0031396 is_a: CCO:P0001433 ! regulation of protein modification process relationship: has_participant CCO:B0057974 ! RN139_HUMAN [Term] id: CCO:P0001431 name: negative regulation of protein ubiquitination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the addition of ubiquitin moieties to a protein." [GOC:mah] synonym: "down regulation of protein ubiquitination" EXACT [] synonym: "down-regulation of protein ubiquitination" EXACT [] synonym: "downregulation of protein ubiquitination" EXACT [] synonym: "inhibition of protein ubiquitination" NARROW [] xref: GO:0031397 is_a: CCO:P0001430 ! regulation of protein ubiquitination is_a: CCO:P0001434 ! negative regulation of protein modification process relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0002116 ! NOG1_HUMAN relationship: has_participant CCO:B0025044 ! KPCG_HUMAN relationship: has_participant CCO:B0055404 ! GSH1_HUMAN [Term] id: CCO:P0001432 name: positive regulation of protein ubiquitination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin moieties to a protein." [GOC:mah] synonym: "activation of protein ubiquitination" NARROW [] synonym: "stimulation of protein ubiquitination" NARROW [] synonym: "up regulation of protein ubiquitination" EXACT [] synonym: "up-regulation of protein ubiquitination" EXACT [] synonym: "upregulation of protein ubiquitination" EXACT [] xref: GO:0031398 is_a: CCO:P0001430 ! regulation of protein ubiquitination is_a: CCO:P0001435 ! positive regulation of protein modification process relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0019462 ! UB2D1_HUMAN relationship: has_participant CCO:B0056531 ! LRRK2_HUMAN relationship: has_participant CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:P0001433 name: regulation of protein modification process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] subset: gosubset_prok xref: GO:0031399 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process [Term] id: CCO:P0001434 name: negative regulation of protein modification process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] synonym: "down regulation of protein modification" EXACT [] synonym: "down-regulation of protein modification" EXACT [] synonym: "downregulation of protein modification" EXACT [] synonym: "inhibition of protein modification" NARROW [] xref: GO:0031400 is_a: CCO:P0001433 ! regulation of protein modification process is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process [Term] id: CCO:P0001435 name: positive regulation of protein modification process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] synonym: "activation of protein modification" NARROW [] synonym: "stimulation of protein modification" NARROW [] synonym: "up regulation of protein modification" EXACT [] synonym: "up-regulation of protein modification" EXACT [] synonym: "upregulation of protein modification" EXACT [] xref: GO:0031401 is_a: CCO:P0001433 ! regulation of protein modification process is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process relationship: has_participant CCO:B0054750 ! ATG7_HUMAN relationship: has_participant CCO:B0058658 ! ATG10_HUMAN [Term] id: CCO:P0001436 name: regulation of mRNA cleavage namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mRNA cleavage, any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner." [GOC:mah] xref: GO:0031437 is_a: CCO:P0002925 ! regulation of mRNA processing [Term] id: CCO:P0001437 name: negative regulation of mRNA cleavage namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cleavage." [GOC:mah] synonym: "down regulation of mRNA cleavage" EXACT [] synonym: "down-regulation of mRNA cleavage" EXACT [] synonym: "downregulation of mRNA cleavage" EXACT [] synonym: "inhibition of mRNA cleavage" NARROW [] xref: GO:0031438 is_a: CCO:P0001436 ! regulation of mRNA cleavage is_a: CCO:P0002927 ! negative regulation of mRNA processing [Term] id: CCO:P0001438 name: positive regulation of mRNA cleavage namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mRNA cleavage." [GOC:mah] synonym: "activation of mRNA cleavage" NARROW [] synonym: "stimulation of mRNA cleavage" NARROW [] synonym: "up regulation of mRNA cleavage" EXACT [] synonym: "up-regulation of mRNA cleavage" EXACT [] synonym: "upregulation of mRNA cleavage" EXACT [] xref: GO:0031439 is_a: CCO:P0001436 ! regulation of mRNA cleavage is_a: CCO:P0002926 ! positive regulation of mRNA processing [Term] id: CCO:P0001439 name: regulation of mRNA 3'-end processing namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule." [GOC:mah] xref: GO:0031440 is_a: CCO:P0002925 ! regulation of mRNA processing [Term] id: CCO:P0001440 name: negative regulation of mRNA 3'-end processing namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-end processing." [GOC:mah] synonym: "down regulation of mRNA 3'-end processing" EXACT [] synonym: "down-regulation of mRNA 3'-end processing" EXACT [] synonym: "downregulation of mRNA 3'-end processing" EXACT [] synonym: "inhibition of mRNA 3'-end processing" NARROW [] xref: GO:0031441 is_a: CCO:P0001439 ! regulation of mRNA 3'-end processing is_a: CCO:P0002927 ! negative regulation of mRNA processing relationship: has_participant CCO:B0002086 ! BARD1_HUMAN [Term] id: CCO:P0001441 name: positive regulation of mRNA 3'-end processing namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing." [GOC:mah] synonym: "activation of mRNA 3'-end processing" NARROW [] synonym: "stimulation of mRNA 3'-end processing" NARROW [] synonym: "up regulation of mRNA 3'-end processing" EXACT [] synonym: "up-regulation of mRNA 3'-end processing" EXACT [] synonym: "upregulation of mRNA 3'-end processing" EXACT [] xref: GO:0031442 is_a: CCO:P0001439 ! regulation of mRNA 3'-end processing is_a: CCO:P0002926 ! positive regulation of mRNA processing relationship: has_participant CCO:B0055805 ! NCBP1_HUMAN [Term] id: CCO:P0001442 name: regulation of heterochromatin formation namespace: biological_process def: "Any process that modulates the frequency, rate, extent or location of heterochromatin formation." [GOC:mah] xref: GO:0031445 is_a: CCO:P0000469 ! regulation of chromatin assembly or disassembly [Term] id: CCO:P0001443 name: negative regulation of heterochromatin formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of heterochromatin formation." [GOC:mah] synonym: "down regulation of heterochromatin formation" EXACT [] synonym: "down-regulation of heterochromatin formation" EXACT [] synonym: "downregulation of heterochromatin formation" EXACT [] synonym: "inhibition of heterochromatin formation" NARROW [] xref: GO:0031452 is_a: CCO:P0001442 ! regulation of heterochromatin formation is_a: CCO:P0002554 ! negative regulation of chromatin assembly or disassembly [Term] id: CCO:P0001444 name: positive regulation of heterochromatin formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of heterochromatin formation." [GOC:mah] synonym: "activation of heterochromatin formation" NARROW [] synonym: "stimulation of heterochromatin formation" NARROW [] synonym: "up regulation of heterochromatin formation" EXACT [] synonym: "up-regulation of heterochromatin formation" EXACT [] synonym: "upregulation of heterochromatin formation" EXACT [] xref: GO:0031453 is_a: CCO:P0001442 ! regulation of heterochromatin formation is_a: CCO:P0002555 ! positive regulation of chromatin assembly or disassembly [Term] id: CCO:P0001445 name: regulation of extent of heterochromatin formation namespace: biological_process def: "Any process that modulates the extent or location of heterochromatin formation." [GOC:mah] synonym: "regulation of heterochromatin spreading" RELATED [] xref: GO:0031454 is_a: CCO:P0001442 ! regulation of heterochromatin formation [Term] id: CCO:P0001446 name: regulation of mating type switching namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus." [GOC:mah] xref: GO:0031494 is_a: CCO:P0002409 ! regulation of cell differentiation is_a: CCO:P0003015 ! regulation of DNA metabolic process relationship: regulates CCO:P0000798 ! mating type switching [Term] id: CCO:P0001447 name: negative regulation of mating type switching namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mating type switching." [GOC:mah] synonym: "down regulation of mating type switching" EXACT [] synonym: "down-regulation of mating type switching" EXACT [] synonym: "downregulation of mating type switching" EXACT [] synonym: "inhibition of mating type switching" NARROW [] xref: GO:0031495 is_a: CCO:P0001446 ! regulation of mating type switching is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0003016 ! negative regulation of DNA metabolic process relationship: negatively_regulates CCO:P0000798 ! mating type switching [Term] id: CCO:P0001448 name: positive regulation of mating type switching namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mating type switching." [GOC:mah] synonym: "activation of mating type switching" NARROW [] synonym: "stimulation of mating type switching" NARROW [] synonym: "up regulation of mating type switching" EXACT [] synonym: "up-regulation of mating type switching" EXACT [] synonym: "upregulation of mating type switching" EXACT [] xref: GO:0031496 is_a: CCO:P0001446 ! regulation of mating type switching is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0003017 ! positive regulation of DNA metabolic process relationship: positively_regulates CCO:P0000798 ! mating type switching [Term] id: CCO:P0001449 name: regulation of anthocyanin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah] synonym: "regulation of anthocyanin metabolism" EXACT [] xref: GO:0031537 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001450 name: negative regulation of anthocyanin metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah] synonym: "down regulation of anthocyanin metabolic process" EXACT [] synonym: "down-regulation of anthocyanin metabolic process" EXACT [] synonym: "downregulation of anthocyanin metabolic process" EXACT [] synonym: "inhibition of anthocyanin metabolic process" NARROW [] synonym: "negative regulation of anthocyanin metabolism" EXACT [] xref: GO:0031538 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001449 ! regulation of anthocyanin metabolic process [Term] id: CCO:P0001451 name: positive regulation of anthocyanin metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins." [GOC:mah] synonym: "activation of anthocyanin metabolic process" NARROW [] synonym: "positive regulation of anthocyanin metabolism" EXACT [] synonym: "stimulation of anthocyanin metabolic process" NARROW [] synonym: "up regulation of anthocyanin metabolic process" EXACT [] synonym: "up-regulation of anthocyanin metabolic process" EXACT [] synonym: "upregulation of anthocyanin metabolic process" EXACT [] xref: GO:0031539 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001449 ! regulation of anthocyanin metabolic process [Term] id: CCO:P0001452 name: regulation of anthocyanin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah] synonym: "regulation of anthocyanin anabolism" EXACT [] synonym: "regulation of anthocyanin biosynthesis" EXACT [] synonym: "regulation of anthocyanin formation" EXACT [] synonym: "regulation of anthocyanin synthesis" EXACT [] xref: GO:0031540 is_a: CCO:P0000881 ! regulation of flavonoid biosynthetic process is_a: CCO:P0001449 ! regulation of anthocyanin metabolic process [Term] id: CCO:P0001453 name: negative regulation of anthocyanin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah] synonym: "down regulation of anthocyanin biosynthetic process" EXACT [] synonym: "down-regulation of anthocyanin biosynthetic process" EXACT [] synonym: "downregulation of anthocyanin biosynthetic process" EXACT [] synonym: "inhibition of anthocyanin biosynthetic process" NARROW [] synonym: "negative regulation of anthocyanin anabolism" EXACT [] synonym: "negative regulation of anthocyanin biosynthesis" EXACT [] synonym: "negative regulation of anthocyanin formation" EXACT [] synonym: "negative regulation of anthocyanin synthesis" EXACT [] xref: GO:0031541 is_a: CCO:P0000883 ! negative regulation of flavonoid biosynthetic process is_a: CCO:P0001450 ! negative regulation of anthocyanin metabolic process is_a: CCO:P0001452 ! regulation of anthocyanin biosynthetic process [Term] id: CCO:P0001454 name: positive regulation of anthocyanin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins." [GOC:mah] synonym: "activation of anthocyanin biosynthetic process" NARROW [] synonym: "positive regulation of anthocyanin anabolism" EXACT [] synonym: "positive regulation of anthocyanin biosynthesis" EXACT [] synonym: "positive regulation of anthocyanin formation" EXACT [] synonym: "positive regulation of anthocyanin synthesis" EXACT [] synonym: "stimulation of anthocyanin biosynthetic process" NARROW [] synonym: "up regulation of anthocyanin biosynthetic process" EXACT [] synonym: "up-regulation of anthocyanin biosynthetic process" EXACT [] synonym: "upregulation of anthocyanin biosynthetic process" EXACT [] xref: GO:0031542 is_a: CCO:P0000882 ! positive regulation of flavonoid biosynthetic process is_a: CCO:P0001451 ! positive regulation of anthocyanin metabolic process is_a: CCO:P0001452 ! regulation of anthocyanin biosynthetic process [Term] id: CCO:P0001455 name: brain-derived neurotrophic factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands." [GOC:mah] synonym: "BDNF receptor signaling pathway" EXACT [] synonym: "BDNF signalling pathway" EXACT [] synonym: "brain-derived neurotrophic factor receptor signalling pathway" EXACT [] xref: GO:0031547 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:P0001456 name: regulation of brain-derived neurotrophic factor receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah] synonym: "regulation of BDNF receptor signaling pathway" EXACT [] synonym: "regulation of BDNF receptor signalling pathway" EXACT [] synonym: "regulation of brain-derived neurotrophic factor receptor signalling pathway" EXACT [] xref: GO:0031548 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0001455 ! brain-derived neurotrophic factor receptor signaling pathway [Term] id: CCO:P0001457 name: negative regulation of brain-derived neurotrophic factor receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah] synonym: "down regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] synonym: "down-regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] synonym: "downregulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] synonym: "inhibition of brain-derived neurotrophic factor receptor signaling pathway" NARROW [] synonym: "negative regulation of BDNF receptor signaling pathway" EXACT [] synonym: "negative regulation of BDNF receptor signalling pathway" EXACT [] synonym: "negative regulation of brain-derived neurotrophic factor receptor signalling pathway" EXACT [] xref: GO:0031549 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001456 ! regulation of brain-derived neurotrophic factor receptor signaling pathway relationship: negatively_regulates CCO:P0001455 ! brain-derived neurotrophic factor receptor signaling pathway [Term] id: CCO:P0001458 name: positive regulation of brain-derived neurotrophic factor receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway." [GOC:mah] synonym: "activation of brain-derived neurotrophic factor receptor signaling pathway" NARROW [] synonym: "positive regulation of BDNF receptor signaling pathway" EXACT [] synonym: "positive regulation of BDNF receptor signalling pathway" EXACT [] synonym: "positive regulation of brain-derived neurotrophic factor receptor signalling pathway" EXACT [] synonym: "stimulation of brain-derived neurotrophic factor receptor signaling pathway" NARROW [] synonym: "up regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] synonym: "up-regulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] synonym: "upregulation of brain-derived neurotrophic factor receptor signaling pathway" EXACT [] xref: GO:0031550 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001456 ! regulation of brain-derived neurotrophic factor receptor signaling pathway relationship: positively_regulates CCO:P0001455 ! brain-derived neurotrophic factor receptor signaling pathway [Term] id: CCO:P0001459 name: regulation of brain-derived neurotrophic factor receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor receptor activity." [GOC:mah] synonym: "regulation of BDNF receptor activity" EXACT [] xref: GO:0031551 is_a: CCO:P0001456 ! regulation of brain-derived neurotrophic factor receptor signaling pathway [Term] id: CCO:P0001460 name: negative regulation of brain-derived neurotrophic factor receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of brain-derived neurotrophic factor receptor activity." [GOC:mah] synonym: "down regulation of brain-derived neurotrophic factor receptor activity" EXACT [] synonym: "down-regulation of brain-derived neurotrophic factor receptor activity" EXACT [] synonym: "downregulation of brain-derived neurotrophic factor receptor activity" EXACT [] synonym: "inhibition of brain-derived neurotrophic factor receptor activity" NARROW [] synonym: "negative regulation of BDNF receptor activity" EXACT [] xref: GO:0031552 is_a: CCO:P0001457 ! negative regulation of brain-derived neurotrophic factor receptor signaling pathway is_a: CCO:P0001459 ! regulation of brain-derived neurotrophic factor receptor activity [Term] id: CCO:P0001461 name: positive regulation of brain-derived neurotrophic factor receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor receptor activity." [GOC:mah] synonym: "activation of brain-derived neurotrophic factor receptor activity" NARROW [] synonym: "positive regulation of BDNF receptor activity" EXACT [] synonym: "stimulation of brain-derived neurotrophic factor receptor activity" NARROW [] synonym: "up regulation of brain-derived neurotrophic factor receptor activity" EXACT [] synonym: "up-regulation of brain-derived neurotrophic factor receptor activity" EXACT [] synonym: "upregulation of brain-derived neurotrophic factor receptor activity" EXACT [] xref: GO:0031553 is_a: CCO:P0001458 ! positive regulation of brain-derived neurotrophic factor receptor signaling pathway is_a: CCO:P0001459 ! regulation of brain-derived neurotrophic factor receptor activity [Term] id: CCO:P0001462 name: regulation of transcription termination namespace: biological_process def: "Any process that modulates the frequency, rate, extent, or location of transcription termination." [GOC:mlg] xref: GO:0031554 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process is_a: CCO:P0002175 ! regulation of protein complex disassembly is_a: CCO:P0002369 ! regulation of transcription [Term] id: CCO:P0001463 name: transcriptional attenuation namespace: biological_process def: "Regulation of transcription through variation in where transcription termination occurs." [GOC:dh, GOC:mlg, ISBN:0198542682] xref: GO:0031555 is_a: CCO:P0001462 ! regulation of transcription termination [Term] id: CCO:P0001464 name: transcriptional attenuation by ribosome namespace: biological_process def: "A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as availabe amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch." [GOC:dh, GOC:mlg, ISBN:0198542682] synonym: "ribosome-mediated transcriptional " EXACT [GOC:dph, GOC:tb] xref: GO:0031556 is_a: CCO:P0001463 ! transcriptional attenuation [Term] id: CCO:P0001465 name: induction of programmed cell death in response to chemical stimulus namespace: biological_process def: "A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus." [GOC:mah] synonym: "induction of programmed cell death in response to chemical substance" EXACT [] xref: GO:0031557 is_a: CCO:P0001050 ! induction of programmed cell death relationship: has_participant CCO:B0020611 ! GRIK2_HUMAN [Term] id: CCO:P0001466 name: induction of apoptosis in response to chemical stimulus namespace: biological_process def: "Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus." [GOC:mah] synonym: "induction of apoptosis in response to chemical substance" EXACT [] xref: GO:0031558 is_a: CCO:P0000831 ! induction of apoptosis by extracellular signals is_a: CCO:P0001465 ! induction of programmed cell death in response to chemical stimulus [Term] id: CCO:P0001467 name: transcription antitermination namespace: biological_process def: "Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond a termination site." [ISBN:0198577788, PMID:12456320] synonym: "transcriptional readthrough" EXACT [] xref: GO:0031564 is_a: CCO:P0001463 ! transcriptional attenuation [Term] id: CCO:P0001468 name: replication fork arrest at rDNA repeats namespace: biological_process def: "A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer." [GOC:mah, GOC:vw] synonym: "replication fork arrest at ribosomal DNA repeats" EXACT [] synonym: "replication fork blocking at rDNA repeats" EXACT [] xref: GO:0031582 is_a: CCO:P0002159 ! replication fork arrest [Term] id: CCO:P0001469 name: G-protein signaling, phospholipase D activating pathway namespace: biological_process def: "A G-protein coupled signaling pathway that results in the activation of phospholipase D, causing an increase in cellular levels of phosphatidic acid." [GOC:mah, PMID:11812783, PMID:15924269] synonym: "G-protein signalling, phospholipase D activating pathway" EXACT [] xref: GO:0031583 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0043822 ! EDN1_HUMAN [Term] id: CCO:P0001470 name: phospholipase D activation namespace: biological_process def: "The series of molecular signals that results in the upregulation of phospholipase D activity in response to the initial signal." [GOC:mah] xref: GO:0031584 is_a: CCO:P0001469 ! G-protein signaling, phospholipase D activating pathway [Term] id: CCO:P0001471 name: regulation of inositol-1,4,5-triphosphate receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of the IP3 receptor." [GOC:dph, GOC:mah] synonym: "regulation of IP3 receptor activity" EXACT [GOC:dph] xref: GO:0031585 is_a: CCO:P0000884 ! regulation of signal transduction [Term] id: CCO:P0001472 name: negative regulation of inositol-1,4,5-triphosphate receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the IP3 receptor." [GOC:dph, GOC:mah] synonym: "down regulation of IP3 receptor activity" EXACT [] synonym: "down-regulation of IP3 receptor activity" EXACT [] synonym: "downregulation of IP3 receptor activity" EXACT [] synonym: "inhibition of IP3 receptor activity" NARROW [] synonym: "negative regulation of IP3 receptor activity" RELATED [GOC:dph] xref: GO:0031586 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001471 ! regulation of inositol-1,4,5-triphosphate receptor activity [Term] id: CCO:P0001473 name: positive regulation of inositol-1,4,5-triphosphate receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of the IP3 receptor." [GOC:dph, GOC:mah] synonym: "activation of IP3 receptor activity" NARROW [] synonym: "positive regulation of IP3 receptor activity" EXACT [GOC:dph] synonym: "stimulation of IP3 receptor activity" NARROW [] synonym: "up regulation of IP3 receptor activity" EXACT [] synonym: "up-regulation of IP3 receptor activity" EXACT [] synonym: "upregulation of IP3 receptor activity" EXACT [] xref: GO:0031587 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001471 ! regulation of inositol-1,4,5-triphosphate receptor activity [Term] id: CCO:P0001474 name: regulation of synaptic vesicle fusion to presynaptic membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah] xref: GO:0031630 is_a: CCO:P0001418 ! regulation of vesicle fusion [Term] id: CCO:P0001475 name: negative regulation of synaptic vesicle fusion to presynaptic membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah] synonym: "down regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] synonym: "down-regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] synonym: "downregulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] synonym: "inhibition of synaptic vesicle fusion to presynaptic membrane" NARROW [] xref: GO:0031631 is_a: CCO:P0001419 ! negative regulation of vesicle fusion is_a: CCO:P0001474 ! regulation of synaptic vesicle fusion to presynaptic membrane [Term] id: CCO:P0001476 name: positive regulation of synaptic vesicle fusion to presynaptic membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane." [GOC:mah] synonym: "activation of synaptic vesicle fusion to presynaptic membrane" NARROW [] synonym: "stimulation of synaptic vesicle fusion to presynaptic membrane" NARROW [] synonym: "up regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] synonym: "up-regulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] synonym: "upregulation of synaptic vesicle fusion to presynaptic membrane" EXACT [] xref: GO:0031632 is_a: CCO:P0001420 ! positive regulation of vesicle fusion is_a: CCO:P0001474 ! regulation of synaptic vesicle fusion to presynaptic membrane [Term] id: CCO:P0001477 name: opioid receptor, adenylate cyclase inhibiting pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP." [GOC:mah] xref: GO:0031635 is_a: CCO:P0000732 ! G-protein signaling, adenylate cyclase inhibiting pathway [Term] id: CCO:P0001478 name: regulation of neuronal synaptic plasticity in response to neurotrophin namespace: biological_process def: "The process by which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah, PMID:8703078] synonym: "neurotrophin-induced neuronal synaptic plasticity" EXACT [] xref: GO:0031637 is_a: CCO:P0002785 ! regulation of neuronal synaptic plasticity [Term] id: CCO:P0001479 name: regulation of myelination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] xref: GO:0031641 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0001480 name: negative regulation of myelination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] synonym: "down regulation of myelination" EXACT [] synonym: "down-regulation of myelination" EXACT [] synonym: "downregulation of myelination" EXACT [] synonym: "inhibition of myelination" NARROW [] xref: GO:0031642 is_a: CCO:P0001479 ! regulation of myelination is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0039858 ! KLK8_HUMAN [Term] id: CCO:P0001481 name: positive regulation of myelination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] synonym: "activation of myelination" NARROW [] synonym: "stimulation of myelination" NARROW [] synonym: "up regulation of myelination" EXACT [] synonym: "up-regulation of myelination" EXACT [] synonym: "upregulation of myelination" EXACT [] xref: GO:0031643 is_a: CCO:P0001479 ! regulation of myelination is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0054876 ! TRFE_HUMAN [Term] id: CCO:P0001482 name: regulation of protein stability namespace: biological_process def: "Any process that affects the structure and integrity of a protein by altering the likelihood of its degradation or aggregation." [GOC:dph, GOC:mah, GOC:tb] subset: goslim_pir subset: gosubset_prok xref: GO:0031647 is_a: CCO:P0001008 ! posttranscriptional regulation of gene expression relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0005442 ! FBX7_HUMAN relationship: has_participant CCO:B0005943 ! APTX_HUMAN relationship: has_participant CCO:B0054863 ! APOA2_HUMAN [Term] id: CCO:P0001483 name: protein destabilization namespace: biological_process def: "Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation." [GOC:mah] synonym: "negative regulation of protein stability" EXACT [] xref: GO:0031648 is_a: CCO:P0001482 ! regulation of protein stability relationship: has_participant CCO:B0058149 ! ISOC2_HUMAN relationship: has_participant CCO:B0059050 ! DAPLE_HUMAN [Term] id: CCO:P0001484 name: lipopolysaccharide-mediated signaling pathway namespace: biological_process def: "The series of molecular signals generated in response to detection of lipopolysaccharide." [GOC:mah] synonym: "lipopolysaccharide-mediated signalling pathway" EXACT [] synonym: "LPS-mediated signaling pathway" EXACT [] xref: GO:0031663 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0055215 ! NOS3_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:P0001485 name: regulation of lipopolysaccharide-mediated signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah] synonym: "regulation of lipopolysaccharide-mediated signalling pathway" EXACT [] synonym: "regulation of LPS-mediated signaling pathway" EXACT [] xref: GO:0031664 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0001484 ! lipopolysaccharide-mediated signaling pathway [Term] id: CCO:P0001486 name: negative regulation of lipopolysaccharide-mediated signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah] synonym: "down regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] synonym: "down-regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] synonym: "downregulation of lipopolysaccharide-mediated signaling pathway" EXACT [] synonym: "inhibition of lipopolysaccharide-mediated signaling pathway" NARROW [] synonym: "negative regulation of lipopolysaccharide-mediated signalling pathway" EXACT [] synonym: "negative regulation of LPS-mediated signaling pathway" EXACT [] xref: GO:0031665 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001485 ! regulation of lipopolysaccharide-mediated signaling pathway relationship: has_participant CCO:B0006002 ! TRIB1_HUMAN relationship: has_participant CCO:B0056756 ! SIGIR_HUMAN relationship: negatively_regulates CCO:P0001484 ! lipopolysaccharide-mediated signaling pathway [Term] id: CCO:P0001487 name: positive regulation of lipopolysaccharide-mediated signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide." [GOC:mah] synonym: "activation of lipopolysaccharide-mediated signaling pathway" NARROW [] synonym: "positive regulation of lipopolysaccharide-mediated signalling pathway" EXACT [] synonym: "positive regulation of LPS-mediated signaling pathway" EXACT [] synonym: "stimulation of lipopolysaccharide-mediated signaling pathway" NARROW [] synonym: "up regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] synonym: "up-regulation of lipopolysaccharide-mediated signaling pathway" EXACT [] synonym: "upregulation of lipopolysaccharide-mediated signaling pathway" EXACT [] xref: GO:0031666 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001485 ! regulation of lipopolysaccharide-mediated signaling pathway relationship: positively_regulates CCO:P0001484 ! lipopolysaccharide-mediated signaling pathway [Term] id: CCO:P0001488 name: primary cell septum biogenesis namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of the constituents of the primary cell septum following nuclear division." [GOC:mah] xref: GO:0031671 is_a: CCO:P0001637 ! cytokinetic process relationship: part_of CCO:P0000454 ! barrier septum formation [Term] id: CCO:P0001489 name: heterotrimeric G-protein complex cycle namespace: biological_process def: "The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits." [GOC:nln] xref: GO:0031684 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0001490 name: negative regulation of synaptic plasticity namespace: biological_process def: "A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah] synonym: "down regulation of synaptic plasticity" EXACT [] synonym: "down-regulation of synaptic plasticity" EXACT [] synonym: "downregulation of synaptic plasticity" EXACT [] synonym: "inhibition of synaptic plasticity" NARROW [] xref: GO:0031914 is_a: CCO:P0002784 ! regulation of synaptic plasticity is_a: CCO:P0002959 ! negative regulation of synaptic transmission [Term] id: CCO:P0001491 name: positive regulation of synaptic plasticity namespace: biological_process def: "A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:mah] synonym: "activation of synaptic plasticity" NARROW [] synonym: "stimulation of synaptic plasticity" NARROW [] synonym: "up regulation of synaptic plasticity" EXACT [] synonym: "up-regulation of synaptic plasticity" EXACT [] synonym: "upregulation of synaptic plasticity" EXACT [] xref: GO:0031915 is_a: CCO:P0002784 ! regulation of synaptic plasticity is_a: CCO:P0002960 ! positive regulation of synaptic transmission [Term] id: CCO:P0001492 name: regulation of synaptic metaplasticity namespace: biological_process def: "A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594] xref: GO:0031916 is_a: CCO:P0002784 ! regulation of synaptic plasticity [Term] id: CCO:P0001493 name: negative regulation of synaptic metaplasticity namespace: biological_process def: "A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594] synonym: "down regulation of synaptic metaplasticity" EXACT [] synonym: "down-regulation of synaptic metaplasticity" EXACT [] synonym: "downregulation of synaptic metaplasticity" EXACT [] synonym: "inhibition of synaptic metaplasticity" NARROW [] xref: GO:0031917 is_a: CCO:P0001490 ! negative regulation of synaptic plasticity is_a: CCO:P0001492 ! regulation of synaptic metaplasticity [Term] id: CCO:P0001494 name: positive regulation of synaptic metaplasticity namespace: biological_process def: "A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require." [GOC:mah, PMID:8658594] synonym: "activation of synaptic metaplasticity" NARROW [] synonym: "stimulation of synaptic metaplasticity" NARROW [] synonym: "up regulation of synaptic metaplasticity" EXACT [] synonym: "up-regulation of synaptic metaplasticity" EXACT [] synonym: "upregulation of synaptic metaplasticity" EXACT [] xref: GO:0031918 is_a: CCO:P0001491 ! positive regulation of synaptic plasticity is_a: CCO:P0001492 ! regulation of synaptic metaplasticity [Term] id: CCO:P0001495 name: TOR signaling pathway namespace: biological_process def: "A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors." [PMID:12372295] comment: Note that this term should not be confused with 'torso signaling pathway ; GO:0008293', although torso is abbreviated 'tor'. synonym: "target of rapamycin signaling pathway" EXACT [] synonym: "target of rapamycin signalling pathway" EXACT [] synonym: "TOR signalling pathway" EXACT [] xref: GO:0031929 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0001496 name: mitochondrial signaling pathway namespace: biological_process def: "A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function." [GOC:jh, PMID:15068799] synonym: "mitochondrial signalling pathway" EXACT [] synonym: "retrograde response" EXACT [] xref: GO:0031930 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0001497 name: regulation of chromatin silencing namespace: biological_process def: "Any process that affects the rate, extent or location of chromatin silencing." [GOC:mah] synonym: "regulation of heterochromatic silencing" RELATED [] xref: GO:0031935 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0001442 ! regulation of heterochromatin formation relationship: regulates CCO:P0000648 ! chromatin silencing [Term] id: CCO:P0001498 name: negative regulation of chromatin silencing namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin silencing." [GOC:mah] synonym: "down regulation of chromatin silencing" EXACT [] synonym: "down-regulation of chromatin silencing" EXACT [] synonym: "downregulation of chromatin silencing" EXACT [] synonym: "inhibition of chromatin silencing" NARROW [] synonym: "negative regulation of heterochromatic silencing" EXACT [] xref: GO:0031936 is_a: CCO:P0001443 ! negative regulation of heterochromatin formation is_a: CCO:P0001497 ! regulation of chromatin silencing relationship: negatively_regulates CCO:P0000648 ! chromatin silencing [Term] id: CCO:P0001499 name: positive regulation of chromatin silencing namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromatin silencing." [GOC:mah] synonym: "activation of chromatin silencing" NARROW [] synonym: "positive regulation of heterochromatic silencing" EXACT [] synonym: "stimulation of chromatin silencing" NARROW [] synonym: "up regulation of chromatin silencing" EXACT [] synonym: "up-regulation of chromatin silencing" EXACT [] synonym: "upregulation of chromatin silencing" EXACT [] xref: GO:0031937 is_a: CCO:P0001444 ! positive regulation of heterochromatin formation is_a: CCO:P0001497 ! regulation of chromatin silencing relationship: positively_regulates CCO:P0000648 ! chromatin silencing [Term] id: CCO:P0001500 name: regulation of chromatin silencing at telomere namespace: biological_process def: "Any process that affects the rate, extent or location of chromatin silencing at telomeres." [GOC:mah] synonym: "regulation of heterochromatic silencing at telomere" EXACT [] xref: GO:0031938 is_a: CCO:P0001497 ! regulation of chromatin silencing relationship: regulates CCO:P0000653 ! chromatin silencing at telomere [Term] id: CCO:P0001501 name: negative regulation of chromatin silencing at telomere namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin silencing at telomeres." [GOC:mah] synonym: "down regulation of chromatin silencing at telomere" EXACT [] synonym: "down-regulation of chromatin silencing at telomere" EXACT [] synonym: "downregulation of chromatin silencing at telomere" EXACT [] synonym: "inhibition of chromatin silencing at telomere" NARROW [] synonym: "negative regulation of heterochromatic silencing at telomere" EXACT [] xref: GO:0031939 is_a: CCO:P0001498 ! negative regulation of chromatin silencing is_a: CCO:P0001500 ! regulation of chromatin silencing at telomere relationship: negatively_regulates CCO:P0000653 ! chromatin silencing at telomere [Term] id: CCO:P0001502 name: positive regulation of chromatin silencing at telomere namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres." [GOC:mah] synonym: "activation of chromatin silencing at telomere" NARROW [] synonym: "positive regulation of heterochromatic silencing at telomere" EXACT [] synonym: "stimulation of chromatin silencing at telomere" NARROW [] synonym: "up regulation of chromatin silencing at telomere" EXACT [] synonym: "up-regulation of chromatin silencing at telomere" EXACT [] synonym: "upregulation of chromatin silencing at telomere" EXACT [] xref: GO:0031940 is_a: CCO:P0001499 ! positive regulation of chromatin silencing is_a: CCO:P0001500 ! regulation of chromatin silencing at telomere relationship: positively_regulates CCO:P0000653 ! chromatin silencing at telomere [Term] id: CCO:P0001503 name: regulation of glucocorticoid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah] synonym: "regulation of glucocorticoid metabolism" EXACT [] xref: GO:0031943 is_a: CCO:P0001141 ! regulation of steroid metabolic process is_a: CCO:P0001608 ! regulation of hormone metabolic process relationship: has_participant CCO:B0055148 ! GALA_HUMAN relationship: has_participant CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:P0001504 name: negative regulation of glucocorticoid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah] synonym: "down regulation of glucocorticoid metabolic process" EXACT [] synonym: "down-regulation of glucocorticoid metabolic process" EXACT [] synonym: "downregulation of glucocorticoid metabolic process" EXACT [] synonym: "inhibition of glucocorticoid metabolic process" NARROW [] synonym: "negative regulation of glucocorticoid metabolism" EXACT [] xref: GO:0031944 is_a: CCO:P0001503 ! regulation of glucocorticoid metabolic process is_a: CCO:P0001609 ! negative regulation of hormone metabolic process is_a: CCO:P0002623 ! negative regulation of steroid metabolic process [Term] id: CCO:P0001505 name: positive regulation of glucocorticoid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids." [GOC:mah] synonym: "activation of glucocorticoid metabolic process" NARROW [] synonym: "positive regulation of glucocorticoid metabolism" EXACT [] synonym: "stimulation of glucocorticoid metabolic process" NARROW [] synonym: "up regulation of glucocorticoid metabolic process" EXACT [] synonym: "up-regulation of glucocorticoid metabolic process" EXACT [] synonym: "upregulation of glucocorticoid metabolic process" EXACT [] xref: GO:0031945 is_a: CCO:P0001503 ! regulation of glucocorticoid metabolic process is_a: CCO:P0001610 ! positive regulation of hormone metabolic process is_a: CCO:P0002624 ! positive regulation of steroid metabolic process [Term] id: CCO:P0001506 name: regulation of glucocorticoid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah] xref: GO:0031946 is_a: CCO:P0001503 ! regulation of glucocorticoid metabolic process is_a: CCO:P0002745 ! regulation of hormone biosynthetic process is_a: CCO:P0002962 ! regulation of steroid biosynthetic process [Term] id: CCO:P0001507 name: negative regulation of glucocorticoid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah] synonym: "down regulation of glucocorticoid biosynthetic process" EXACT [] synonym: "down-regulation of glucocorticoid biosynthetic process" EXACT [] synonym: "downregulation of glucocorticoid biosynthetic process" EXACT [] synonym: "inhibition of glucocorticoid biosynthetic process" NARROW [] xref: GO:0031947 is_a: CCO:P0001504 ! negative regulation of glucocorticoid metabolic process is_a: CCO:P0001506 ! regulation of glucocorticoid biosynthetic process is_a: CCO:P0001611 ! negative regulation of hormone biosynthetic process [Term] id: CCO:P0001508 name: positive regulation of glucocorticoid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids." [GOC:mah] synonym: "activation of glucocorticoid biosynthetic process" NARROW [] synonym: "stimulation of glucocorticoid biosynthetic process" NARROW [] synonym: "up regulation of glucocorticoid biosynthetic process" EXACT [] synonym: "up-regulation of glucocorticoid biosynthetic process" EXACT [] synonym: "upregulation of glucocorticoid biosynthetic process" EXACT [] xref: GO:0031948 is_a: CCO:P0001505 ! positive regulation of glucocorticoid metabolic process is_a: CCO:P0001506 ! regulation of glucocorticoid biosynthetic process is_a: CCO:P0002746 ! positive regulation of hormone biosynthetic process [Term] id: CCO:P0001509 name: regulation of glucocorticoid catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah] xref: GO:0031949 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0001503 ! regulation of glucocorticoid metabolic process [Term] id: CCO:P0001510 name: negative regulation of glucocorticoid catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah] synonym: "down regulation of glucocorticoid catabolic process" EXACT [] synonym: "down-regulation of glucocorticoid catabolic process" EXACT [] synonym: "downregulation of glucocorticoid catabolic process" EXACT [] synonym: "inhibition of glucocorticoid catabolic process" NARROW [] xref: GO:0031950 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0001504 ! negative regulation of glucocorticoid metabolic process is_a: CCO:P0001509 ! regulation of glucocorticoid catabolic process [Term] id: CCO:P0001511 name: positive regulation of glucocorticoid catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids." [GOC:mah] synonym: "activation of glucocorticoid catabolic process" NARROW [] synonym: "stimulation of glucocorticoid catabolic process" NARROW [] synonym: "up regulation of glucocorticoid catabolic process" EXACT [] synonym: "up-regulation of glucocorticoid catabolic process" EXACT [] synonym: "upregulation of glucocorticoid catabolic process" EXACT [] xref: GO:0031951 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0001505 ! positive regulation of glucocorticoid metabolic process is_a: CCO:P0001509 ! regulation of glucocorticoid catabolic process [Term] id: CCO:P0001512 name: regulation of protein amino acid autophosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] xref: GO:0031952 is_a: CCO:P0000500 ! regulation of protein amino acid phosphorylation [Term] id: CCO:P0001513 name: negative regulation of protein amino acid autophosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] synonym: "down regulation of protein amino acid autophosphorylation" EXACT [] synonym: "down-regulation of protein amino acid autophosphorylation" EXACT [] synonym: "downregulation of protein amino acid autophosphorylation" EXACT [] synonym: "inhibition of protein amino acid autophosphorylation" NARROW [] xref: GO:0031953 is_a: CCO:P0000501 ! negative regulation of protein amino acid phosphorylation is_a: CCO:P0001512 ! regulation of protein amino acid autophosphorylation relationship: has_participant CCO:B0001487 ! JUN_HUMAN relationship: has_participant CCO:B0055145 ! ENPP1_HUMAN relationship: has_participant CCO:B0055574 ! NAL12_HUMAN [Term] id: CCO:P0001514 name: positive regulation of protein amino acid autophosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] synonym: "activation of protein amino acid autophosphorylation" NARROW [] synonym: "stimulation of protein amino acid autophosphorylation" NARROW [] synonym: "up regulation of protein amino acid autophosphorylation" EXACT [] synonym: "up-regulation of protein amino acid autophosphorylation" EXACT [] synonym: "upregulation of protein amino acid autophosphorylation" EXACT [] xref: GO:0031954 is_a: CCO:P0000502 ! positive regulation of protein amino acid phosphorylation is_a: CCO:P0001512 ! regulation of protein amino acid autophosphorylation [Term] id: CCO:P0001515 name: corticosteroid receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor." [GOC:mah, PMID:11027914, PMID:12606724] synonym: "corticosteroid receptor signalling pathway" EXACT [] xref: GO:0031958 is_a: CCO:P0001278 ! steroid hormone receptor signaling pathway [Term] id: CCO:P0001516 name: mineralocorticoid receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor." [GOC:mah, PMID:11027914, PMID:12606724] synonym: "mineralocorticoid receptor signalling pathway" EXACT [] xref: GO:0031959 is_a: CCO:P0001515 ! corticosteroid receptor signaling pathway [Term] id: CCO:P0001517 name: bombesin receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands." [GOC:mah] synonym: "bombesin receptor signalling pathway" EXACT [] xref: GO:0031989 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0001518 name: regulation of fatty acid beta-oxidation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation." [GOC:mah] xref: GO:0031998 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0002686 ! regulation of fatty acid oxidation relationship: has_participant CCO:B0054797 ! DCMC_HUMAN [Term] id: CCO:P0001519 name: negative regulation of fatty acid beta-oxidation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation." [GOC:mah] synonym: "down regulation of fatty acid beta-oxidation" EXACT [] synonym: "down-regulation of fatty acid beta-oxidation" EXACT [] synonym: "downregulation of fatty acid beta-oxidation" EXACT [] synonym: "inhibition of fatty acid beta-oxidation" NARROW [] xref: GO:0031999 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0001518 ! regulation of fatty acid beta-oxidation is_a: CCO:P0002688 ! negative regulation of fatty acid oxidation [Term] id: CCO:P0001520 name: positive regulation of fatty acid beta-oxidation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation." [GOC:mah] synonym: "activation of fatty acid beta-oxidation" NARROW [] synonym: "stimulation of fatty acid beta-oxidation" NARROW [] synonym: "up regulation of fatty acid beta-oxidation" EXACT [] synonym: "up-regulation of fatty acid beta-oxidation" EXACT [] synonym: "upregulation of fatty acid beta-oxidation" EXACT [] xref: GO:0032000 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0001518 ! regulation of fatty acid beta-oxidation is_a: CCO:P0002687 ! positive regulation of fatty acid oxidation relationship: has_participant CCO:B0055786 ! PPARA_HUMAN [Term] id: CCO:P0001521 name: signal transduction during conjugation with cellular fusion namespace: biological_process def: "The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:mah] xref: GO:0032005 is_a: CCO:P0000708 ! signal transduction [Term] id: CCO:P0001522 name: regulation of TOR signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the TOR signaling pathway." [GOC:mah] synonym: "regulation of target of rapamycin signaling pathway" EXACT [] synonym: "regulation of target of rapamycin signalling pathway" EXACT [] synonym: "regulation of TOR signalling pathway" EXACT [] xref: GO:0032006 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0001495 ! TOR signaling pathway [Term] id: CCO:P0001523 name: negative regulation of TOR signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the TOR signaling pathway." [GOC:mah] synonym: "down regulation of TOR signaling pathway" EXACT [] synonym: "down-regulation of TOR signaling pathway" EXACT [] synonym: "downregulation of TOR signaling pathway" EXACT [] synonym: "inhibition of TOR signaling pathway" NARROW [] synonym: "negative regulation of target of rapamycin signaling pathway" EXACT [] synonym: "negative regulation of target of rapamycin signalling pathway" EXACT [] synonym: "negative regulation of TOR signalling pathway" EXACT [] xref: GO:0032007 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001522 ! regulation of TOR signaling pathway relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: negatively_regulates CCO:P0001495 ! TOR signaling pathway [Term] id: CCO:P0001524 name: positive regulation of TOR signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the TOR signaling pathway." [GOC:mah] synonym: "activation of TOR signaling pathway" NARROW [] synonym: "positive regulation of target of rapamycin signaling pathway" EXACT [] synonym: "positive regulation of target of rapamycin signalling pathway" EXACT [] synonym: "positive regulation of TOR signalling pathway" EXACT [] synonym: "stimulation of TOR signaling pathway" NARROW [] synonym: "up regulation of TOR signaling pathway" EXACT [] synonym: "up-regulation of TOR signaling pathway" EXACT [] synonym: "upregulation of TOR signaling pathway" EXACT [] xref: GO:0032008 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001522 ! regulation of TOR signaling pathway relationship: positively_regulates CCO:P0001495 ! TOR signaling pathway [Term] id: CCO:P0001525 name: ARF protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state." [GOC:mah] xref: GO:0032011 is_a: CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:P0001526 name: regulation of ARF protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ARF protein signal transduction." [GOC:mah] xref: GO:0032012 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: has_participant CCO:B0005359 ! GBF1_HUMAN relationship: has_participant CCO:B0024694 ! BIG1_HUMAN relationship: has_participant CCO:B0024696 ! BIG2_HUMAN relationship: has_participant CCO:B0032438 ! FBX8_HUMAN relationship: has_participant CCO:B0032439 ! Q8IWE1_HUMAN relationship: has_participant CCO:B0032440 ! Q8IXA8_HUMAN relationship: has_participant CCO:B0053775 ! PSD1_HUMAN relationship: has_participant CCO:B0053860 ! A6NIF2_HUMAN relationship: has_participant CCO:B0053888 ! A6NKV9_HUMAN relationship: has_participant CCO:B0054214 ! B1AHH4_HUMAN relationship: has_participant CCO:B0054215 ! B1AHH5_HUMAN relationship: has_participant CCO:B0054216 ! B1AHH6_HUMAN relationship: has_participant CCO:B0054217 ! B1AHH7_HUMAN relationship: has_participant CCO:B0054218 ! B1AHH8_HUMAN relationship: has_participant CCO:B0054219 ! B1AHI0_HUMAN relationship: has_participant CCO:B0054232 ! B1AKX7_HUMAN relationship: has_participant CCO:B0054516 ! CYH3_HUMAN relationship: has_participant CCO:B0056063 ! CYH1_HUMAN relationship: has_participant CCO:B0056389 ! Q59F87_HUMAN relationship: has_participant CCO:B0056416 ! Q59HG0_HUMAN relationship: has_participant CCO:B0056485 ! IQEC2_HUMAN relationship: has_participant CCO:B0056491 ! Q5JUX1_HUMAN relationship: has_participant CCO:B0056626 ! BIG3_HUMAN relationship: has_participant CCO:B0056728 ! IQEC1_HUMAN relationship: has_participant CCO:B0057584 ! PSD4_HUMAN relationship: has_participant CCO:B0058410 ! CYH2_HUMAN relationship: has_participant CCO:B0058482 ! PSD2_HUMAN relationship: has_participant CCO:B0058963 ! PSD3_HUMAN relationship: has_participant CCO:B0059155 ! CYH4_HUMAN relationship: has_participant CCO:B0059262 ! IQEC3_HUMAN relationship: regulates CCO:P0001525 ! ARF protein signal transduction [Term] id: CCO:P0001527 name: negative regulation of ARF protein signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ARF protein signal transduction." [GOC:mah] synonym: "down regulation of ARF protein signal transduction" EXACT [] synonym: "down-regulation of ARF protein signal transduction" EXACT [] synonym: "downregulation of ARF protein signal transduction" EXACT [] synonym: "inhibition of ARF protein signal transduction" NARROW [] xref: GO:0032013 is_a: CCO:P0001526 ! regulation of ARF protein signal transduction is_a: CCO:P0002700 ! negative regulation of Ras protein signal transduction relationship: negatively_regulates CCO:P0001525 ! ARF protein signal transduction [Term] id: CCO:P0001528 name: positive regulation of ARF protein signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction." [GOC:mah] synonym: "activation of ARF protein signal transduction" NARROW [] synonym: "stimulation of ARF protein signal transduction" NARROW [] synonym: "up regulation of ARF protein signal transduction" EXACT [] synonym: "up-regulation of ARF protein signal transduction" EXACT [] synonym: "upregulation of ARF protein signal transduction" EXACT [] xref: GO:0032014 is_a: CCO:P0001526 ! regulation of ARF protein signal transduction is_a: CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: positively_regulates CCO:P0001525 ! ARF protein signal transduction [Term] id: CCO:P0001529 name: regulation of Ran protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Ran protein signal transduction." [GOC:mah] xref: GO:0032015 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: regulates CCO:P0001398 ! Ran protein signal transduction [Term] id: CCO:P0001530 name: negative regulation of Ran protein signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Ran protein signal transduction." [GOC:mah] synonym: "down regulation of Ran protein signal transduction" EXACT [] synonym: "down-regulation of Ran protein signal transduction" EXACT [] synonym: "downregulation of Ran protein signal transduction" EXACT [] synonym: "inhibition of Ran protein signal transduction" NARROW [] xref: GO:0032016 is_a: CCO:P0001529 ! regulation of Ran protein signal transduction is_a: CCO:P0002700 ! negative regulation of Ras protein signal transduction relationship: negatively_regulates CCO:P0001398 ! Ran protein signal transduction [Term] id: CCO:P0001531 name: positive regulation of Ran protein signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction." [GOC:mah] synonym: "activation of Ran protein signal transduction" NARROW [] synonym: "stimulation of Ran protein signal transduction" NARROW [] synonym: "up regulation of Ran protein signal transduction" EXACT [] synonym: "up-regulation of Ran protein signal transduction" EXACT [] synonym: "upregulation of Ran protein signal transduction" EXACT [] xref: GO:0032017 is_a: CCO:P0001529 ! regulation of Ran protein signal transduction is_a: CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: positively_regulates CCO:P0001398 ! Ran protein signal transduction [Term] id: CCO:P0001532 name: positive regulation of insulin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah] synonym: "activation of insulin secretion" NARROW [] synonym: "stimulation of insulin secretion" NARROW [] synonym: "up regulation of insulin secretion" EXACT [] synonym: "up-regulation of insulin secretion" EXACT [] synonym: "upregulation of insulin secretion" EXACT [] xref: GO:0032024 is_a: CCO:P0002747 ! positive regulation of hormone secretion is_a: CCO:P0002956 ! regulation of insulin secretion relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0018508 ! HXK4_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0041239 ! PSMD9_HUMAN relationship: has_participant CCO:B0058800 ! CAN10_HUMAN [Term] id: CCO:P0001533 name: negative regulation of translation in response to stress namespace: biological_process def: "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "down regulation of translation in response to stress" EXACT [] synonym: "down-regulation of translation in response to stress" EXACT [] synonym: "downregulation of translation in response to stress" EXACT [] synonym: "inhibition of translation in response to stress" NARROW [] xref: GO:0032055 is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0002240 ! regulation of translation in response to stress [Term] id: CCO:P0001534 name: positive regulation of translation in response to stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "activation of translation in response to stress" NARROW [] synonym: "stimulation of translation in response to stress" NARROW [] synonym: "up regulation of translation in response to stress" EXACT [] synonym: "up-regulation of translation in response to stress" EXACT [] synonym: "upregulation of translation in response to stress" EXACT [] xref: GO:0032056 is_a: CCO:P0002240 ! regulation of translation in response to stress is_a: CCO:P0002524 ! positive regulation of translation [Term] id: CCO:P0001535 name: negative regulation of translational initiation in response to stress namespace: biological_process def: "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "down regulation of translation initiation in response to stress" EXACT [] synonym: "down-regulation of translation initiation in response to stress" EXACT [] synonym: "downregulation of translation initiation in response to stress" EXACT [] synonym: "inhibition of translation initiation in response to stress" NARROW [] xref: GO:0032057 is_a: CCO:P0001533 ! negative regulation of translation in response to stress is_a: CCO:P0002243 ! regulation of translational initiation in response to stress is_a: CCO:P0002630 ! negative regulation of translational initiation relationship: has_participant CCO:B0055879 ! EI2BE_HUMAN [Term] id: CCO:P0001536 name: positive regulation of translational initiation in response to stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "activation of translation initiation in response to stress" NARROW [] synonym: "stimulation of translation initiation in response to stress" NARROW [] synonym: "up regulation of translation initiation in response to stress" EXACT [] synonym: "up-regulation of translation initiation in response to stress" EXACT [] synonym: "upregulation of translation initiation in response to stress" EXACT [] xref: GO:0032058 is_a: CCO:P0001534 ! positive regulation of translation in response to stress is_a: CCO:P0002243 ! regulation of translational initiation in response to stress is_a: CCO:P0002631 ! positive regulation of translational initiation [Term] id: CCO:P0001537 name: negative regulation of translation in response to osmotic stress namespace: biological_process def: "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] synonym: "down regulation of translation in response to osmotic stress" EXACT [] synonym: "down-regulation of translation in response to osmotic stress" EXACT [] synonym: "downregulation of translation in response to osmotic stress" EXACT [] synonym: "inhibition of translation in response to osmotic stress" NARROW [] xref: GO:0032061 is_a: CCO:P0001533 ! negative regulation of translation in response to stress is_a: CCO:P0002242 ! regulation of translation in response to osmotic stress [Term] id: CCO:P0001538 name: positive regulation of translation in response to osmotic stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] synonym: "activation of translation in response to osmotic stress" NARROW [] synonym: "stimulation of translation in response to osmotic stress" NARROW [] synonym: "up regulation of translation in response to osmotic stress" EXACT [] synonym: "up-regulation of translation in response to osmotic stress" EXACT [] synonym: "upregulation of translation in response to osmotic stress" EXACT [] xref: GO:0032062 is_a: CCO:P0001534 ! positive regulation of translation in response to stress is_a: CCO:P0002242 ! regulation of translation in response to osmotic stress [Term] id: CCO:P0001539 name: negative regulation of translational initiation in response to osmotic stress namespace: biological_process def: "Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] synonym: "down regulation of translation initiation in response to osmotic stress" EXACT [] synonym: "down-regulation of translation initiation in response to osmotic stress" EXACT [] synonym: "downregulation of translation initiation in response to osmotic stress" EXACT [] synonym: "inhibition of translation initiation in response to osmotic stress" NARROW [] xref: GO:0032063 is_a: CCO:P0001537 ! negative regulation of translation in response to osmotic stress is_a: CCO:P0002244 ! regulation of translational initiation in response to osmotic stress [Term] id: CCO:P0001540 name: positive regulation of translational initiation in response to osmotic stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:mah] synonym: "activation of translation initiation in response to osmotic stress" NARROW [] synonym: "stimulation of translation initiation in response to osmotic stress" NARROW [] synonym: "up regulation of translation initiation in response to osmotic stress" EXACT [] synonym: "up-regulation of translation initiation in response to osmotic stress" EXACT [] synonym: "upregulation of translation initiation in response to osmotic stress" EXACT [] xref: GO:0032064 is_a: CCO:P0001538 ! positive regulation of translation in response to osmotic stress is_a: CCO:P0002244 ! regulation of translational initiation in response to osmotic stress [Term] id: CCO:P0001541 name: negative regulation of NF-kappaB transcription factor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB." [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb] synonym: "NF-kappaB inhibitor" RELATED [] xref: GO:0032088 is_a: CCO:P0002212 ! negative regulation of transcription factor activity relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0018189 ! PYDC1_HUMAN relationship: has_participant CCO:B0039142 ! FOXJ1_HUMAN relationship: has_participant CCO:B0057268 ! COMD7_HUMAN relationship: has_participant CCO:B0058316 ! NALP3_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN [Term] id: CCO:P0001542 name: ascospore-type prospore membrane formation namespace: biological_process def: "The process by which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed." [GOC:clt] synonym: "forespore membrane biosynthesis" EXACT [] synonym: "forespore membrane formation" EXACT [] synonym: "FSM assembly" EXACT [] synonym: "FSM biosynthesis" EXACT [] synonym: "FSM formation" EXACT [] xref: GO:0032120 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001403 ! ascospore-type prospore formation [Term] id: CCO:P0001543 name: medial membrane band formation namespace: biological_process def: "The formation of sterol rich region of the plasma membrane at the cell surface overlying the contractile ring." [PMID:15517003] xref: GO:0032130 is_a: CCO:P0001637 ! cytokinetic process [Term] id: CCO:P0001544 name: contractile ring localization namespace: biological_process def: "The process by which a contractile ring is assembled and/or maintained in a specific location." [GOC:mah] xref: GO:0032187 is_a: CCO:P0001637 ! cytokinetic process [Term] id: CCO:P0001545 name: telomere maintenance via semi-conservative replication namespace: biological_process def: "The process whereby telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors." [GOC:vw, PMID:16598261] synonym: "equal telomere replication" RELATED [] synonym: "telomeric fork progression" NARROW [] synonym: "telomeric replication fork progression" NARROW [] xref: GO:0032201 is_a: CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0001546 name: regulation of telomere maintenance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah] xref: GO:0032204 is_a: CCO:P0001766 ! regulation of chromosome organization and biogenesis is_a: CCO:P0003015 ! regulation of DNA metabolic process relationship: has_participant CCO:B0058731 ! PIF1_HUMAN [Term] id: CCO:P0001547 name: negative regulation of telomere maintenance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah] synonym: "down regulation of telomere maintenance" EXACT [] synonym: "down-regulation of telomere maintenance" EXACT [] synonym: "downregulation of telomere maintenance" EXACT [] synonym: "inhibition of telomere maintenance" NARROW [] xref: GO:0032205 is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis is_a: CCO:P0001546 ! regulation of telomere maintenance is_a: CCO:P0003016 ! negative regulation of DNA metabolic process relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN relationship: has_participant CCO:B0015646 ! ERCC1_HUMAN [Term] id: CCO:P0001548 name: positive regulation of telomere maintenance namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." [GOC:mah] synonym: "activation of telomere maintenance" NARROW [] synonym: "stimulation of telomere maintenance" NARROW [] synonym: "up regulation of telomere maintenance" EXACT [] synonym: "up-regulation of telomere maintenance" EXACT [] synonym: "upregulation of telomere maintenance" EXACT [] xref: GO:0032206 is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis is_a: CCO:P0001546 ! regulation of telomere maintenance is_a: CCO:P0003017 ! positive regulation of DNA metabolic process [Term] id: CCO:P0001549 name: regulation of telomere maintenance via recombination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah] xref: GO:0032207 is_a: CCO:P0000399 ! regulation of mitotic recombination is_a: CCO:P0001546 ! regulation of telomere maintenance [Term] id: CCO:P0001550 name: negative regulation of telomere maintenance via recombination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah] synonym: "down regulation of telomere maintenance via recombination" EXACT [] synonym: "down-regulation of telomere maintenance via recombination" EXACT [] synonym: "downregulation of telomere maintenance via recombination" EXACT [] synonym: "inhibition of telomere maintenance via recombination" NARROW [] xref: GO:0032208 is_a: CCO:P0001547 ! negative regulation of telomere maintenance is_a: CCO:P0001549 ! regulation of telomere maintenance via recombination is_a: CCO:P0002633 ! negative regulation of mitotic recombination [Term] id: CCO:P0001551 name: positive regulation of telomere maintenance via recombination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length." [GOC:mah] synonym: "activation of telomere maintenance via recombination" NARROW [] synonym: "stimulation of telomere maintenance via recombination" NARROW [] synonym: "up regulation of telomere maintenance via recombination" EXACT [] synonym: "up-regulation of telomere maintenance via recombination" EXACT [] synonym: "upregulation of telomere maintenance via recombination" EXACT [] xref: GO:0032209 is_a: CCO:P0001548 ! positive regulation of telomere maintenance is_a: CCO:P0001549 ! regulation of telomere maintenance via recombination is_a: CCO:P0002634 ! positive regulation of mitotic recombination [Term] id: CCO:P0001552 name: regulation of telomere maintenance via telomerase namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah] xref: GO:0032210 is_a: CCO:P0000639 ! regulation of DNA replication is_a: CCO:P0001546 ! regulation of telomere maintenance relationship: regulates CCO:P0000692 ! telomere maintenance via telomerase [Term] id: CCO:P0001553 name: negative regulation of telomere maintenance via telomerase namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah] synonym: "down regulation of telomere maintenance via telomerase activity" EXACT [] synonym: "down-regulation of telomere maintenance via telomerase activity" EXACT [] synonym: "downregulation of telomere maintenance via telomerase activity" EXACT [] synonym: "inhibition of telomere maintenance via telomerase" NARROW [] xref: GO:0032211 is_a: CCO:P0000813 ! negative regulation of DNA replication is_a: CCO:P0001547 ! negative regulation of telomere maintenance is_a: CCO:P0001552 ! regulation of telomere maintenance via telomerase relationship: negatively_regulates CCO:P0000692 ! telomere maintenance via telomerase [Term] id: CCO:P0001554 name: positive regulation of telomere maintenance via telomerase namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase." [GOC:mah] synonym: "activation of telomere maintenance via telomerase" NARROW [] synonym: "stimulation of telomere maintenance via telomerase" NARROW [] synonym: "up regulation of telomere maintenance via telomerase activity" EXACT [] synonym: "up-regulation of telomere maintenance via telomerase activity" EXACT [] synonym: "upregulation of telomere maintenance via telomerase activity" EXACT [] xref: GO:0032212 is_a: CCO:P0001548 ! positive regulation of telomere maintenance is_a: CCO:P0001552 ! regulation of telomere maintenance via telomerase is_a: CCO:P0002528 ! positive regulation of DNA replication relationship: positively_regulates CCO:P0000692 ! telomere maintenance via telomerase [Term] id: CCO:P0001555 name: regulation of telomere maintenance via semi-conservative replication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah] xref: GO:0032213 is_a: CCO:P0000639 ! regulation of DNA replication is_a: CCO:P0001546 ! regulation of telomere maintenance relationship: regulates CCO:P0001545 ! telomere maintenance via semi-conservative replication [Term] id: CCO:P0001556 name: negative regulation of telomere maintenance via semi-conservative replication namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah] synonym: "down regulation of telomere maintenance via semi-conservative replication" EXACT [] synonym: "down-regulation of telomere maintenance via semi-conservative replication" EXACT [] synonym: "downregulation of telomere maintenance via semi-conservative replication" EXACT [] synonym: "inhibition of telomere maintenance via semi-conservative replication" NARROW [] xref: GO:0032214 is_a: CCO:P0000813 ! negative regulation of DNA replication is_a: CCO:P0001547 ! negative regulation of telomere maintenance is_a: CCO:P0001555 ! regulation of telomere maintenance via semi-conservative replication relationship: negatively_regulates CCO:P0001545 ! telomere maintenance via semi-conservative replication [Term] id: CCO:P0001557 name: positive regulation of telomere maintenance via semi-conservative replication namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA." [GOC:mah] synonym: "activation of telomere maintenance via semi-conservative replication" NARROW [] synonym: "stimulation of telomere maintenance via semi-conservative replication" NARROW [] synonym: "up regulation of telomere maintenance via semi-conservative replication" EXACT [] synonym: "up-regulation of telomere maintenance via semi-conservative replication" EXACT [] synonym: "upregulation of telomere maintenance via semi-conservative replication" EXACT [] xref: GO:0032215 is_a: CCO:P0001548 ! positive regulation of telomere maintenance is_a: CCO:P0001555 ! regulation of telomere maintenance via semi-conservative replication is_a: CCO:P0002528 ! positive regulation of DNA replication relationship: positively_regulates CCO:P0001545 ! telomere maintenance via semi-conservative replication [Term] id: CCO:P0001558 name: cell wall catabolic process during cytogamy namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a cell wall during cytogamy." [GOC:mah] xref: GO:0032219 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000447 ! cytogamy [Term] id: CCO:P0001559 name: plasma membrane fusion during cytogamy namespace: biological_process def: "The joining of two or more lipid bilayer membranes that surround cells, during cytogamy." [GOC:mah] xref: GO:0032220 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000447 ! cytogamy [Term] id: CCO:P0001560 name: regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] xref: GO:0032222 is_a: CCO:P0002958 ! regulation of synaptic transmission [Term] id: CCO:P0001561 name: negative regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "down regulation of synaptic transmission, cholinergic" EXACT [] synonym: "down-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "downregulation of synaptic transmission, cholinergic" EXACT [] synonym: "inhibition of synaptic transmission, cholinergic" NARROW [] xref: GO:0032223 is_a: CCO:P0001560 ! regulation of synaptic transmission, cholinergic is_a: CCO:P0002959 ! negative regulation of synaptic transmission relationship: has_participant CCO:B0055143 ! ACES_HUMAN [Term] id: CCO:P0001562 name: positive regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "activation of synaptic transmission, cholinergic" NARROW [] synonym: "stimulation of synaptic transmission, cholinergic" NARROW [] synonym: "up regulation of synaptic transmission, cholinergic" EXACT [] synonym: "up-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "upregulation of synaptic transmission, cholinergic" EXACT [] xref: GO:0032224 is_a: CCO:P0001560 ! regulation of synaptic transmission, cholinergic is_a: CCO:P0002960 ! positive regulation of synaptic transmission [Term] id: CCO:P0001563 name: regulation of synaptic transmission, dopaminergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah] xref: GO:0032225 is_a: CCO:P0002958 ! regulation of synaptic transmission relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN relationship: has_participant CCO:B0055310 ! ACHA7_HUMAN [Term] id: CCO:P0001564 name: positive regulation of synaptic transmission, dopaminergic namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah] synonym: "activation of synaptic transmission, dopaminergic" NARROW [] synonym: "stimulation of synaptic transmission, dopaminergic" NARROW [] synonym: "up regulation of synaptic transmission, dopaminergic" EXACT [] synonym: "up-regulation of synaptic transmission, dopaminergic" EXACT [] synonym: "upregulation of synaptic transmission, dopaminergic" EXACT [] xref: GO:0032226 is_a: CCO:P0001563 ! regulation of synaptic transmission, dopaminergic is_a: CCO:P0002960 ! positive regulation of synaptic transmission [Term] id: CCO:P0001565 name: negative regulation of synaptic transmission, dopaminergic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." [GOC:mah] synonym: "down regulation of synaptic transmission, dopaminergic" EXACT [] synonym: "down-regulation of synaptic transmission, dopaminergic" EXACT [] synonym: "downregulation of synaptic transmission, dopaminergic" EXACT [] synonym: "inhibition of synaptic transmission, dopaminergic" NARROW [] xref: GO:0032227 is_a: CCO:P0001563 ! regulation of synaptic transmission, dopaminergic is_a: CCO:P0002959 ! negative regulation of synaptic transmission [Term] id: CCO:P0001566 name: regulation of synaptic transmission, GABAergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah] xref: GO:0032228 is_a: CCO:P0002958 ! regulation of synaptic transmission relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN [Term] id: CCO:P0001567 name: negative regulation of synaptic transmission, GABAergic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah] synonym: "down regulation of synaptic transmission, GABAergic" EXACT [] synonym: "down-regulation of synaptic transmission, GABAergic" EXACT [] synonym: "downregulation of synaptic transmission, GABAergic" EXACT [] synonym: "inhibition of synaptic transmission, GABAergic" NARROW [] xref: GO:0032229 is_a: CCO:P0001566 ! regulation of synaptic transmission, GABAergic is_a: CCO:P0002959 ! negative regulation of synaptic transmission [Term] id: CCO:P0001568 name: positive regulation of synaptic transmission, GABAergic namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." [GOC:mah] synonym: "activation of synaptic transmission, GABAergic" NARROW [] synonym: "stimulation of synaptic transmission, GABAergic" NARROW [] synonym: "up regulation of synaptic transmission, GABAergic" EXACT [] synonym: "up-regulation of synaptic transmission, GABAergic" EXACT [] synonym: "upregulation of synaptic transmission, GABAergic" EXACT [] xref: GO:0032230 is_a: CCO:P0001566 ! regulation of synaptic transmission, GABAergic is_a: CCO:P0002960 ! positive regulation of synaptic transmission relationship: has_participant CCO:B0055210 ! AA2AR_HUMAN [Term] id: CCO:P0001569 name: regulation of actin filament bundle formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] xref: GO:0032231 is_a: CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis [Term] id: CCO:P0001570 name: negative regulation of actin filament bundle formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "down regulation of actin filament bundle formation" EXACT [] synonym: "down-regulation of actin filament bundle formation" EXACT [] synonym: "downregulation of actin filament bundle formation" EXACT [] synonym: "inhibition of actin filament bundle formation" NARROW [] xref: GO:0032232 is_a: CCO:P0001569 ! regulation of actin filament bundle formation is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001571 name: positive regulation of actin filament bundle formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "activation of actin filament bundle formation" NARROW [] synonym: "stimulation of actin filament bundle formation" NARROW [] synonym: "up regulation of actin filament bundle formation" EXACT [] synonym: "up-regulation of actin filament bundle formation" EXACT [] synonym: "upregulation of actin filament bundle formation" EXACT [] xref: GO:0032233 is_a: CCO:P0001569 ! regulation of actin filament bundle formation is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001572 name: regulation of cellular protein metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah] subset: gosubset_prok synonym: "regulation of cellular protein metabolism" EXACT [] xref: GO:0032268 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001573 name: negative regulation of cellular protein metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah] synonym: "down regulation of cellular protein metabolic process" EXACT [] synonym: "down-regulation of cellular protein metabolic process" EXACT [] synonym: "downregulation of cellular protein metabolic process" EXACT [] synonym: "inhibition of cellular protein metabolic process" NARROW [] synonym: "negative regulation of cellular protein metabolism" EXACT [] xref: GO:0032269 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001572 ! regulation of cellular protein metabolic process [Term] id: CCO:P0001574 name: positive regulation of cellular protein metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." [GOC:mah] synonym: "activation of cellular protein metabolic process" NARROW [] synonym: "positive regulation of cellular protein metabolism" EXACT [] synonym: "stimulation of cellular protein metabolic process" NARROW [] synonym: "up regulation of cellular protein metabolic process" EXACT [] synonym: "up-regulation of cellular protein metabolic process" EXACT [] synonym: "upregulation of cellular protein metabolic process" EXACT [] xref: GO:0032270 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001572 ! regulation of cellular protein metabolic process relationship: has_participant CCO:B0054852 ! INS_HUMAN [Term] id: CCO:P0001575 name: regulation of protein polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "regulation of protein polymerisation" EXACT [] xref: GO:0032271 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process [Term] id: CCO:P0001576 name: negative regulation of protein polymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "down regulation of protein polymerization" EXACT [] synonym: "down-regulation of protein polymerization" EXACT [] synonym: "downregulation of protein polymerization" EXACT [] synonym: "inhibition of protein polymerization" NARROW [] xref: GO:0032272 is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process is_a: CCO:P0001575 ! regulation of protein polymerization [Term] id: CCO:P0001577 name: positive regulation of protein polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "activation of protein polymerization" NARROW [] synonym: "stimulation of protein polymerization" NARROW [] synonym: "up regulation of protein polymerization" EXACT [] synonym: "up-regulation of protein polymerization" EXACT [] synonym: "upregulation of protein polymerization" EXACT [] xref: GO:0032273 is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process is_a: CCO:P0001575 ! regulation of protein polymerization relationship: has_participant CCO:B0054701 ! TPPP_HUMAN [Term] id: CCO:P0001578 name: regulation of gonadotropin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah] synonym: "regulation of gonadotrophin secretion" EXACT [] xref: GO:0032276 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0001579 name: negative regulation of gonadotropin secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah] synonym: "down regulation of gonadotropin secretion" EXACT [] synonym: "down-regulation of gonadotropin secretion" EXACT [] synonym: "downregulation of gonadotropin secretion" EXACT [] synonym: "inhibition of gonadotropin secretion" NARROW [] synonym: "negative regulation of gonadotrophin secretion" EXACT [] xref: GO:0032277 is_a: CCO:P0001578 ! regulation of gonadotropin secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0001580 name: positive regulation of gonadotropin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin." [GOC:mah] synonym: "activation of gonadotropin secretion" NARROW [] synonym: "positive regulation of gonadotrophin secretion" EXACT [] synonym: "stimulation of gonadotropin secretion" NARROW [] synonym: "up regulation of gonadotropin secretion" EXACT [] synonym: "up-regulation of gonadotropin secretion" EXACT [] synonym: "upregulation of gonadotropin secretion" EXACT [] xref: GO:0032278 is_a: CCO:P0001578 ! regulation of gonadotropin secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion [Term] id: CCO:P0001581 name: negative regulation of DNA replication initiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of initiation of DNA replication." [GOC:mah] synonym: "down regulation of DNA replication initiation" EXACT [] synonym: "down-regulation of DNA replication initiation" EXACT [] synonym: "downregulation of DNA replication initiation" EXACT [] synonym: "inhibition of DNA replication initiation" NARROW [] xref: GO:0032297 is_a: CCO:P0000813 ! negative regulation of DNA replication is_a: CCO:P0001247 ! regulation of DNA replication initiation relationship: negatively_regulates CCO:P0000634 ! DNA replication initiation [Term] id: CCO:P0001582 name: positive regulation of DNA replication initiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of initiation of DNA replication." [GOC:mah] synonym: "activation of DNA replication initiation" NARROW [] synonym: "stimulation of DNA replication initiation" NARROW [] synonym: "up regulation of DNA replication initiation" EXACT [] synonym: "up-regulation of DNA replication initiation" EXACT [] synonym: "upregulation of DNA replication initiation" EXACT [] xref: GO:0032298 is_a: CCO:P0001247 ! regulation of DNA replication initiation is_a: CCO:P0002528 ! positive regulation of DNA replication relationship: positively_regulates CCO:P0000634 ! DNA replication initiation [Term] id: CCO:P0001583 name: regulation of ARF GTPase activity namespace: biological_process def: "Any process that modulates the activity of the GTPase ARF." [GOC:mah] xref: GO:0032312 is_a: CCO:P0001589 ! regulation of Ras GTPase activity relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0005397 ! GIT1_HUMAN relationship: has_participant CCO:B0006225 ! ARFG1_HUMAN relationship: has_participant CCO:B0015543 ! SMAP1_HUMAN relationship: has_participant CCO:B0024597 ! CEND3_HUMAN relationship: has_participant CCO:B0024599 ! Q6ZMJ9_HUMAN relationship: has_participant CCO:B0024600 ! CEND1_HUMAN relationship: has_participant CCO:B0033514 ! SMAP2_HUMAN relationship: has_participant CCO:B0033902 ! Q5TA42_HUMAN relationship: has_participant CCO:B0033903 ! CENB1_HUMAN relationship: has_participant CCO:B0033904 ! CENB2_HUMAN relationship: has_participant CCO:B0033965 ! CTLF6_HUMAN relationship: has_participant CCO:B0033967 ! CTLF5_HUMAN relationship: has_participant CCO:B0033969 ! CTLF4_HUMAN relationship: has_participant CCO:B0033970 ! CTLF2_HUMAN relationship: has_participant CCO:B0033972 ! CTLF1_HUMAN relationship: has_participant CCO:B0033973 ! CTLF3_HUMAN relationship: has_participant CCO:B0033974 ! Q86XV2_HUMAN relationship: has_participant CCO:B0043443 ! CENA1_HUMAN relationship: has_participant CCO:B0053961 ! A8K3A2_HUMAN relationship: has_participant CCO:B0054099 ! A8MXL3_HUMAN relationship: has_participant CCO:B0054172 ! B0QYV8_HUMAN relationship: has_participant CCO:B0054173 ! B0QYV9_HUMAN relationship: has_participant CCO:B0054252 ! B1AMF5_HUMAN relationship: has_participant CCO:B0054450 ! DDEF2_HUMAN relationship: has_participant CCO:B0054722 ! HRBL_HUMAN relationship: has_participant CCO:B0055487 ! NUPL_HUMAN relationship: has_participant CCO:B0055967 ! GIT2_HUMAN relationship: has_participant CCO:B0056233 ! Q2V6Q1_HUMAN relationship: has_participant CCO:B0056390 ! Q59FC3_HUMAN relationship: has_participant CCO:B0056566 ! CTLF7_HUMAN relationship: has_participant CCO:B0056980 ! Q6ZMK7_HUMAN relationship: has_participant CCO:B0057021 ! Q6ZNF7_HUMAN relationship: has_participant CCO:B0057296 ! Q86XV5_HUMAN relationship: has_participant CCO:B0057489 ! ARFG2_HUMAN relationship: has_participant CCO:B0057946 ! DDFL1_HUMAN relationship: has_participant CCO:B0057961 ! CTLFX_HUMAN relationship: has_participant CCO:B0058317 ! CENG3_HUMAN relationship: has_participant CCO:B0058318 ! CENB5_HUMAN relationship: has_participant CCO:B0058417 ! CENG1_HUMAN relationship: has_participant CCO:B0058833 ! ARFG3_HUMAN relationship: has_participant CCO:B0058850 ! CENA2_HUMAN relationship: has_participant CCO:B0059225 ! DDEF1_HUMAN relationship: has_participant CCO:B0059263 ! CENG2_HUMAN relationship: part_of CCO:P0001526 ! regulation of ARF protein signal transduction [Term] id: CCO:P0001584 name: regulation of Rab GTPase activity namespace: biological_process def: "Any process that modulates the activity of a GTPase of the Rab family." [GOC:mah] xref: GO:0032313 is_a: CCO:P0001589 ! regulation of Ras GTPase activity relationship: has_participant CCO:B0001408 ! EVI5_HUMAN relationship: has_participant CCO:B0002042 ! SGSM3_HUMAN relationship: has_participant CCO:B0002254 ! RBGP1_HUMAN relationship: has_participant CCO:B0005279 ! TBC17_HUMAN relationship: has_participant CCO:B0015232 ! Q9NSP8_HUMAN relationship: has_participant CCO:B0015235 ! Q8IVV0_HUMAN relationship: has_participant CCO:B0018142 ! EVI5L_HUMAN relationship: has_participant CCO:B0020567 ! Q9NXX9_HUMAN relationship: has_participant CCO:B0027580 ! A0JNU9_HUMAN relationship: has_participant CCO:B0027581 ! TBCD1_HUMAN relationship: has_participant CCO:B0030726 ! TB22B_HUMAN relationship: has_participant CCO:B0030729 ! TB22A_HUMAN relationship: has_participant CCO:B0031753 ! Q5T270_HUMAN relationship: has_participant CCO:B0031754 ! TBC13_HUMAN relationship: has_participant CCO:B0033512 ! RBG1L_HUMAN relationship: has_participant CCO:B0033513 ! Q5JZA9_HUMAN relationship: has_participant CCO:B0041721 ! B0QY80_HUMAN relationship: has_participant CCO:B0053792 ! A6NDL0_HUMAN relationship: has_participant CCO:B0053796 ! TBC3B_HUMAN relationship: has_participant CCO:B0053802 ! A6NE50_HUMAN relationship: has_participant CCO:B0053809 ! TBC3E_HUMAN relationship: has_participant CCO:B0053830 ! A6NG99_HUMAN relationship: has_participant CCO:B0053838 ! TBC3L_HUMAN relationship: has_participant CCO:B0053858 ! TB3L2_HUMAN relationship: has_participant CCO:B0053871 ! A6NJH0_HUMAN relationship: has_participant CCO:B0053944 ! A7E244_HUMAN relationship: has_participant CCO:B0053946 ! A7E2X8_HUMAN relationship: has_participant CCO:B0053951 ! A8K007_HUMAN relationship: has_participant CCO:B0053979 ! A8K8E1_HUMAN relationship: has_participant CCO:B0054028 ! A8MTI5_HUMAN relationship: has_participant CCO:B0054031 ! A8MTM7_HUMAN relationship: has_participant CCO:B0054046 ! A8MUT4_HUMAN relationship: has_participant CCO:B0054053 ! A8MV28_HUMAN relationship: has_participant CCO:B0054101 ! A8MXQ6_HUMAN relationship: has_participant CCO:B0054165 ! B0QYI1_HUMAN relationship: has_participant CCO:B0054166 ! B0QYI3_HUMAN relationship: has_participant CCO:B0054174 ! B0QYW0_HUMAN relationship: has_participant CCO:B0054449 ! SGSM2_HUMAN relationship: has_participant CCO:B0054548 ! TBC12_HUMAN relationship: has_participant CCO:B0054793 ! TBCD8_HUMAN relationship: has_participant CCO:B0055277 ! UBP6_HUMAN relationship: has_participant CCO:B0055812 ! TBC8B_HUMAN relationship: has_participant CCO:B0056087 ! Q15635_HUMAN relationship: has_participant CCO:B0056210 ! TBC28_HUMAN relationship: has_participant CCO:B0056218 ! SGSM1_HUMAN relationship: has_participant CCO:B0056232 ! Q2TU37_HUMAN relationship: has_participant CCO:B0056262 ! TBC25_HUMAN relationship: has_participant CCO:B0056319 ! TB10B_HUMAN relationship: has_participant CCO:B0056326 ! Q4V771_HUMAN relationship: has_participant CCO:B0056554 ! Q5SZL4_HUMAN relationship: has_participant CCO:B0056555 ! Q5SZL5_HUMAN relationship: has_participant CCO:B0056556 ! Q5SZL8_HUMAN relationship: has_participant CCO:B0056557 ! Q5SZM1_HUMAN relationship: has_participant CCO:B0056558 ! Q5SZM2_HUMAN relationship: has_participant CCO:B0056607 ! Q5TBQ6_HUMAN relationship: has_participant CCO:B0056608 ! Q5TBQ7_HUMAN relationship: has_participant CCO:B0056609 ! GRTP1_HUMAN relationship: has_participant CCO:B0056695 ! TBC9B_HUMAN relationship: has_participant CCO:B0056722 ! Q6DCB4_HUMAN relationship: has_participant CCO:B0056724 ! TBC3G_HUMAN relationship: has_participant CCO:B0056822 ! TBC3C_HUMAN relationship: has_participant CCO:B0056900 ! Q6PD72_HUMAN relationship: has_participant CCO:B0057027 ! Q6ZNK8_HUMAN relationship: has_participant CCO:B0057062 ! TBCD9_HUMAN relationship: has_participant CCO:B0057114 ! Q7L1K8_HUMAN relationship: has_participant CCO:B0057247 ! TBC26_HUMAN relationship: has_participant CCO:B0057264 ! Q86VM8_HUMAN relationship: has_participant CCO:B0057313 ! Q86YV2_HUMAN relationship: has_participant CCO:B0057332 ! TB10C_HUMAN relationship: has_participant CCO:B0057394 ! TBC21_HUMAN relationship: has_participant CCO:B0057411 ! TBC3A_HUMAN relationship: has_participant CCO:B0057435 ! Q8N1Y0_HUMAN relationship: has_participant CCO:B0057437 ! Q8N250_HUMAN relationship: has_participant CCO:B0057478 ! TBC19_HUMAN relationship: has_participant CCO:B0057573 ! Q8NCR5_HUMAN relationship: has_participant CCO:B0057906 ! TBC16_HUMAN relationship: has_participant CCO:B0057910 ! TBC15_HUMAN relationship: has_participant CCO:B0057953 ! TBCK_HUMAN relationship: has_participant CCO:B0058070 ! TBCD5_HUMAN relationship: has_participant CCO:B0058086 ! US6NL_HUMAN relationship: has_participant CCO:B0058172 ! TBC20_HUMAN relationship: has_participant CCO:B0058193 ! Q96DH7_HUMAN relationship: has_participant CCO:B0058194 ! WDR67_HUMAN relationship: has_participant CCO:B0058284 ! Q96MB8_HUMAN relationship: has_participant CCO:B0058305 ! CF170_HUMAN relationship: has_participant CCO:B0058350 ! ALS2_HUMAN relationship: has_participant CCO:B0058554 ! TB10A_HUMAN relationship: has_participant CCO:B0058586 ! TBD2A_HUMAN relationship: has_participant CCO:B0058741 ! Q9H7M0_HUMAN relationship: has_participant CCO:B0058928 ! TBC23_HUMAN relationship: has_participant CCO:B0059033 ! TBCD7_HUMAN relationship: has_participant CCO:B0059060 ! TBC14_HUMAN relationship: has_participant CCO:B0059116 ! TBC29_HUMAN relationship: has_participant CCO:B0059231 ! TBC24_HUMAN relationship: has_participant CCO:B0059268 ! TBD2B_HUMAN relationship: has_participant CCO:B0059275 ! Q9UQ19_HUMAN relationship: has_participant CCO:B0059308 ! TBC30_HUMAN relationship: has_participant CCO:B0059421 ! Q9Y6Y5_HUMAN relationship: has_participant CCO:B0059422 ! Q9Y6Y6_HUMAN relationship: part_of CCO:P0001629 ! regulation of Rab protein signal transduction [Term] id: CCO:P0001585 name: regulation of Rac GTPase activity namespace: biological_process def: "Any process that modulates the activity of a GTPase of the Rac family." [GOC:mah] xref: GO:0032314 is_a: CCO:P0001590 ! regulation of Rho GTPase activity relationship: has_participant CCO:B0023039 ! STMN3_HUMAN relationship: part_of CCO:P0001982 ! regulation of Rac protein signal transduction [Term] id: CCO:P0001586 name: regulation of Ral GTPase activity namespace: biological_process def: "Any process that modulates the activity of a GTPase of the Ral family." [GOC:mah] xref: GO:0032315 is_a: CCO:P0001589 ! regulation of Ras GTPase activity relationship: part_of CCO:P0001631 ! regulation of Ral protein signal transduction [Term] id: CCO:P0001587 name: regulation of Ran GTPase activity namespace: biological_process def: "Any process that modulates the activity of a GTPase of the Ran family." [GOC:mah] xref: GO:0032316 is_a: CCO:P0001589 ! regulation of Ras GTPase activity relationship: part_of CCO:P0001529 ! regulation of Ran protein signal transduction [Term] id: CCO:P0001588 name: regulation of Rap GTPase activity namespace: biological_process def: "Any process that modulates the activity of a GTPase of the Rap family." [GOC:mah] xref: GO:0032317 is_a: CCO:P0001589 ! regulation of Ras GTPase activity relationship: part_of CCO:P0001633 ! regulation of Rap protein signal transduction [Term] id: CCO:P0001589 name: regulation of Ras GTPase activity namespace: biological_process def: "Any process that modulates the activity of a GTPase of the Ras superfamily." [GOC:mah] xref: GO:0032318 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: part_of CCO:P0002698 ! regulation of Ras protein signal transduction [Term] id: CCO:P0001590 name: regulation of Rho GTPase activity namespace: biological_process def: "Any process that modulates the activity of a GTPase of the Rho family." [GOC:mah] xref: GO:0032319 is_a: CCO:P0001589 ! regulation of Ras GTPase activity relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: part_of CCO:P0001985 ! regulation of Rho protein signal transduction [Term] id: CCO:P0001591 name: positive regulation of Ras GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of a GTPase of the Ras superfamily." [GOC:mah] synonym: "stimulation of Ras GTPase activity" NARROW [] synonym: "up regulation of Ras GTPase activity" EXACT [] synonym: "up-regulation of Ras GTPase activity" EXACT [] synonym: "upregulation of Ras GTPase activity" EXACT [] xref: GO:0032320 is_a: CCO:P0001589 ! regulation of Ras GTPase activity relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN [Term] id: CCO:P0001592 name: positive regulation of Rho GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of a GTPase of the Rho family." [GOC:mah] synonym: "stimulation of Rho GTPase activity" NARROW [] synonym: "up regulation of Rho GTPase activity" EXACT [] synonym: "up-regulation of Rho GTPase activity" EXACT [] synonym: "upregulation of Rho GTPase activity" EXACT [] xref: GO:0032321 is_a: CCO:P0001590 ! regulation of Rho GTPase activity is_a: CCO:P0001591 ! positive regulation of Ras GTPase activity [Term] id: CCO:P0001593 name: regulation of chondrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] xref: GO:0032330 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0001594 name: negative regulation of chondrocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "down regulation of chondrocyte differentiation" EXACT [] synonym: "down-regulation of chondrocyte differentiation" EXACT [] synonym: "downregulation of chondrocyte differentiation" EXACT [] synonym: "inhibition of chondrocyte differentiation" NARROW [] xref: GO:0032331 is_a: CCO:P0001593 ! regulation of chondrocyte differentiation is_a: CCO:P0002410 ! negative regulation of cell differentiation relationship: has_participant CCO:B0001516 ! BMP4_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN [Term] id: CCO:P0001595 name: positive regulation of chondrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "activation of chondrocyte differentiation" NARROW [] synonym: "stimulation of chondrocyte differentiation" NARROW [] synonym: "up regulation of chondrocyte differentiation" EXACT [] synonym: "up-regulation of chondrocyte differentiation" EXACT [] synonym: "upregulation of chondrocyte differentiation" EXACT [] xref: GO:0032332 is_a: CCO:P0001593 ! regulation of chondrocyte differentiation is_a: CCO:P0002411 ! positive regulation of cell differentiation relationship: has_participant CCO:B0056004 ! IHH_HUMAN [Term] id: CCO:P0001596 name: regulation of activin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell or group of cells." [GOC:mah] xref: GO:0032335 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0001597 name: negative regulation of activin secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of activin from a cell or group of cells." [GOC:mah] synonym: "down regulation of activin secretion" EXACT [] synonym: "down-regulation of activin secretion" EXACT [] synonym: "downregulation of activin secretion" EXACT [] synonym: "inhibition of activin secretion" NARROW [] xref: GO:0032336 is_a: CCO:P0001596 ! regulation of activin secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0001598 name: positive regulation of activin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell or group of cells." [GOC:mah] synonym: "activation of activin secretion" NARROW [] synonym: "stimulation of activin secretion" NARROW [] synonym: "up regulation of activin secretion" EXACT [] synonym: "up-regulation of activin secretion" EXACT [] synonym: "upregulation of activin secretion" EXACT [] xref: GO:0032337 is_a: CCO:P0001596 ! regulation of activin secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion [Term] id: CCO:P0001599 name: regulation of inhibin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells." [GOC:mah] xref: GO:0032338 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0001600 name: negative regulation of inhibin secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells." [GOC:mah] synonym: "down regulation of inhibin secretion" EXACT [] synonym: "down-regulation of inhibin secretion" EXACT [] synonym: "downregulation of inhibin secretion" EXACT [] synonym: "inhibition of inhibin secretion" NARROW [] xref: GO:0032339 is_a: CCO:P0001599 ! regulation of inhibin secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0001601 name: positive regulation of inhibin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell or group of cells." [GOC:mah] synonym: "activation of inhibin secretion" NARROW [] synonym: "stimulation of inhibin secretion" NARROW [] synonym: "up regulation of inhibin secretion" EXACT [] synonym: "up-regulation of inhibin secretion" EXACT [] synonym: "upregulation of inhibin secretion" EXACT [] xref: GO:0032340 is_a: CCO:P0001599 ! regulation of inhibin secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion [Term] id: CCO:P0001602 name: regulation of aldosterone metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah] synonym: "regulation of aldosterone metabolism" EXACT [] xref: GO:0032344 is_a: CCO:P0001141 ! regulation of steroid metabolic process is_a: CCO:P0001608 ! regulation of hormone metabolic process relationship: has_participant CCO:B0055840 ! KCMA1_HUMAN [Term] id: CCO:P0001603 name: negative regulation of aldosterone metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah] synonym: "down regulation of aldosterone metabolic process" EXACT [] synonym: "down-regulation of aldosterone metabolic process" EXACT [] synonym: "downregulation of aldosterone metabolic process" EXACT [] synonym: "inhibition of aldosterone metabolic process" NARROW [] synonym: "negative regulation of aldosterone metabolism" EXACT [] xref: GO:0032345 is_a: CCO:P0001602 ! regulation of aldosterone metabolic process is_a: CCO:P0001609 ! negative regulation of hormone metabolic process is_a: CCO:P0002623 ! negative regulation of steroid metabolic process [Term] id: CCO:P0001604 name: positive regulation of aldosterone metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone." [GOC:mah] synonym: "activation of aldosterone metabolic process" NARROW [] synonym: "positive regulation of aldosterone metabolism" EXACT [] synonym: "stimulation of aldosterone metabolic process" NARROW [] synonym: "up regulation of aldosterone metabolic process" EXACT [] synonym: "up-regulation of aldosterone metabolic process" EXACT [] synonym: "upregulation of aldosterone metabolic process" EXACT [] xref: GO:0032346 is_a: CCO:P0001602 ! regulation of aldosterone metabolic process is_a: CCO:P0001610 ! positive regulation of hormone metabolic process is_a: CCO:P0002624 ! positive regulation of steroid metabolic process [Term] id: CCO:P0001605 name: regulation of aldosterone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah] xref: GO:0032347 is_a: CCO:P0001602 ! regulation of aldosterone metabolic process is_a: CCO:P0002745 ! regulation of hormone biosynthetic process is_a: CCO:P0002962 ! regulation of steroid biosynthetic process [Term] id: CCO:P0001606 name: negative regulation of aldosterone biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah] synonym: "down regulation of aldosterone biosynthetic process" EXACT [] synonym: "down-regulation of aldosterone biosynthetic process" EXACT [] synonym: "downregulation of aldosterone biosynthetic process" EXACT [] synonym: "inhibition of aldosterone biosynthetic process" NARROW [] xref: GO:0032348 is_a: CCO:P0001603 ! negative regulation of aldosterone metabolic process is_a: CCO:P0001605 ! regulation of aldosterone biosynthetic process is_a: CCO:P0001611 ! negative regulation of hormone biosynthetic process [Term] id: CCO:P0001607 name: positive regulation of aldosterone biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone." [GOC:mah] synonym: "activation of aldosterone biosynthetic process" NARROW [] synonym: "stimulation of aldosterone biosynthetic process" NARROW [] synonym: "up regulation of aldosterone biosynthetic process" EXACT [] synonym: "up-regulation of aldosterone biosynthetic process" EXACT [] synonym: "upregulation of aldosterone biosynthetic process" EXACT [] xref: GO:0032349 is_a: CCO:P0001604 ! positive regulation of aldosterone metabolic process is_a: CCO:P0001605 ! regulation of aldosterone biosynthetic process is_a: CCO:P0002746 ! positive regulation of hormone biosynthetic process relationship: has_participant CCO:B0042130 ! BMP6_HUMAN [Term] id: CCO:P0001608 name: regulation of hormone metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah] synonym: "regulation of hormone metabolism" EXACT [] xref: GO:0032350 is_a: CCO:P0001404 ! regulation of cellular metabolic process relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN [Term] id: CCO:P0001609 name: negative regulation of hormone metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah] synonym: "down regulation of hormone metabolic process" EXACT [] synonym: "down-regulation of hormone metabolic process" EXACT [] synonym: "downregulation of hormone metabolic process" EXACT [] synonym: "inhibition of hormone metabolic process" NARROW [] synonym: "negative regulation of hormone metabolism" EXACT [] xref: GO:0032351 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001608 ! regulation of hormone metabolic process [Term] id: CCO:P0001610 name: positive regulation of hormone metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone." [GOC:mah] synonym: "activation of hormone metabolic process" NARROW [] synonym: "positive regulation of hormone metabolism" EXACT [] synonym: "stimulation of hormone metabolic process" NARROW [] synonym: "up regulation of hormone metabolic process" EXACT [] synonym: "up-regulation of hormone metabolic process" EXACT [] synonym: "upregulation of hormone metabolic process" EXACT [] xref: GO:0032352 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001608 ! regulation of hormone metabolic process [Term] id: CCO:P0001611 name: negative regulation of hormone biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." [GOC:ai] synonym: "down regulation of hormone biosynthetic process" EXACT [] synonym: "down-regulation of hormone biosynthetic process" EXACT [] synonym: "downregulation of hormone biosynthetic process" EXACT [] synonym: "inhibition of hormone biosynthetic process" NARROW [] xref: GO:0032353 is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0001609 ! negative regulation of hormone metabolic process is_a: CCO:P0002745 ! regulation of hormone biosynthetic process [Term] id: CCO:P0001612 name: regulation of mismatch repair namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mismatch repair." [GOC:vk] xref: GO:0032423 is_a: CCO:P0000643 ! regulation of DNA repair relationship: regulates CCO:P0000645 ! mismatch repair [Term] id: CCO:P0001613 name: negative regulation of mismatch repair namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mismatch repair." [GOC:vk] synonym: "down regulation of mismatch repair" EXACT [] synonym: "down-regulation of mismatch repair" EXACT [] synonym: "downregulation of mismatch repair" EXACT [] synonym: "inhibition of mismatch repair" NARROW [] xref: GO:0032424 is_a: CCO:P0001612 ! regulation of mismatch repair is_a: CCO:P0002526 ! negative regulation of DNA repair relationship: negatively_regulates CCO:P0000645 ! mismatch repair [Term] id: CCO:P0001614 name: positive regulation of mismatch repair namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mismatch repair." [GOC:vk] synonym: "activation of mismatch repair" NARROW [] synonym: "stimulation of mismatch repair" NARROW [] synonym: "up regulation of mismatch repair" EXACT [] synonym: "up-regulation of mismatch repair" EXACT [] synonym: "upregulation of mismatch repair" EXACT [] xref: GO:0032425 is_a: CCO:P0001612 ! regulation of mismatch repair is_a: CCO:P0002527 ! positive regulation of DNA repair relationship: has_participant CCO:B0025044 ! KPCG_HUMAN relationship: positively_regulates CCO:P0000645 ! mismatch repair [Term] id: CCO:P0001615 name: regulation of proteasomal ubiquitin-dependent protein catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah] xref: GO:0032434 is_a: CCO:P0001246 ! regulation of proteolysis is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0001616 name: negative regulation of proteasomal ubiquitin-dependent protein catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah] synonym: "down regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] synonym: "down-regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] synonym: "downregulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] synonym: "inhibition of proteasomal ubiquitin-dependent protein catabolic process" NARROW [] xref: GO:0032435 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0001615 ! regulation of proteasomal ubiquitin-dependent protein catabolic process is_a: CCO:P0002578 ! negative regulation of proteolysis relationship: has_participant CCO:B0056066 ! SHH_HUMAN [Term] id: CCO:P0001617 name: positive regulation of proteasomal ubiquitin-dependent protein catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah] synonym: "activation of proteasomal ubiquitin-dependent protein catabolic process" NARROW [] synonym: "stimulation of proteasomal ubiquitin-dependent protein catabolic process" NARROW [] synonym: "up regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] synonym: "up-regulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] synonym: "upregulation of proteasomal ubiquitin-dependent protein catabolic process" EXACT [] xref: GO:0032436 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0001615 ! regulation of proteasomal ubiquitin-dependent protein catabolic process is_a: CCO:P0002579 ! positive regulation of proteolysis relationship: has_participant CCO:B0055404 ! GSH1_HUMAN relationship: has_participant CCO:B0059251 ! STUB1_HUMAN [Term] id: CCO:P0001618 name: regulation of ergosterol biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol." [GOC:mah] xref: GO:0032443 is_a: CCO:P0002962 ! regulation of steroid biosynthetic process [Term] id: CCO:P0001619 name: regulation of protein oligomerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein oligomerization." [GOC:mah] subset: gosubset_prok xref: GO:0032459 is_a: CCO:P0002176 ! regulation of protein complex assembly [Term] id: CCO:P0001620 name: negative regulation of protein oligomerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein oligomerization." [GOC:mah] subset: gosubset_prok synonym: "down regulation of protein oligomerization" EXACT [] synonym: "down-regulation of protein oligomerization" EXACT [] synonym: "downregulation of protein oligomerization" EXACT [] synonym: "inhibition of protein oligomerization" NARROW [] xref: GO:0032460 is_a: CCO:P0001413 ! negative regulation of protein complex assembly is_a: CCO:P0001619 ! regulation of protein oligomerization [Term] id: CCO:P0001621 name: positive regulation of protein oligomerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein oligomerization." [GOC:mah] subset: gosubset_prok synonym: "activation of protein oligomerization" NARROW [] synonym: "induction of protein oligomerization" RELATED [] synonym: "stimulation of protein oligomerization" NARROW [] synonym: "up regulation of protein oligomerization" EXACT [] synonym: "up-regulation of protein oligomerization" EXACT [] synonym: "upregulation of protein oligomerization" EXACT [] xref: GO:0032461 is_a: CCO:P0001414 ! positive regulation of protein complex assembly is_a: CCO:P0001619 ! regulation of protein oligomerization [Term] id: CCO:P0001622 name: regulation of protein homooligomerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein homooligomerization." [GOC:mah] subset: gosubset_prok xref: GO:0032462 is_a: CCO:P0001619 ! regulation of protein oligomerization [Term] id: CCO:P0001623 name: negative regulation of protein homooligomerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein homooligomerization." [GOC:mah] subset: gosubset_prok synonym: "down regulation of protein homooligomerization" EXACT [] synonym: "down-regulation of protein homooligomerization" EXACT [] synonym: "downregulation of protein homooligomerization" EXACT [] synonym: "inhibition of protein homooligomerization" NARROW [] xref: GO:0032463 is_a: CCO:P0001620 ! negative regulation of protein oligomerization is_a: CCO:P0001622 ! regulation of protein homooligomerization [Term] id: CCO:P0001624 name: positive regulation of protein homooligomerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein homooligomerization." [GOC:mah] subset: gosubset_prok synonym: "activation of protein homooligomerization" NARROW [] synonym: "induction of protein homooligomerization" RELATED [] synonym: "stimulation of protein homooligomerization" NARROW [] synonym: "up regulation of protein homooligomerization" EXACT [] synonym: "up-regulation of protein homooligomerization" EXACT [] synonym: "upregulation of protein homooligomerization" EXACT [] xref: GO:0032464 is_a: CCO:P0001621 ! positive regulation of protein oligomerization is_a: CCO:P0001622 ! regulation of protein homooligomerization [Term] id: CCO:P0001625 name: regulation of cytokinesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells." [GOC:mah] xref: GO:0032465 is_a: CCO:P0003078 ! regulation of cell division relationship: has_participant CCO:B0043836 ! BBS4_HUMAN relationship: regulates CCO:P0000453 ! cytokinesis [Term] id: CCO:P0001626 name: negative regulation of cytokinesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis." [GOC:mah] synonym: "down regulation of cytokinesis" EXACT [] synonym: "down-regulation of cytokinesis" EXACT [] synonym: "downregulation of cytokinesis" EXACT [] synonym: "inhibition of cytokinesis" NARROW [] xref: GO:0032466 is_a: CCO:P0001625 ! regulation of cytokinesis is_a: CCO:P0003144 ! negative regulation of cell division relationship: negatively_regulates CCO:P0000453 ! cytokinesis [Term] id: CCO:P0001627 name: positive regulation of cytokinesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytokinesis." [GOC:mah] synonym: "activation of cytokinesis" NARROW [] synonym: "stimulation of cytokinesis" NARROW [] synonym: "up regulation of cytokinesis" EXACT [] synonym: "up-regulation of cytokinesis" EXACT [] synonym: "upregulation of cytokinesis" EXACT [] xref: GO:0032467 is_a: CCO:P0001625 ! regulation of cytokinesis is_a: CCO:P0003143 ! positive regulation of cell division relationship: positively_regulates CCO:P0000453 ! cytokinesis [Term] id: CCO:P0001628 name: Rab protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state." [GOC:mah] xref: GO:0032482 is_a: CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:P0001629 name: regulation of Rab protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Rab protein signal transduction." [GOC:mah] xref: GO:0032483 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: has_participant CCO:B0002042 ! SGSM3_HUMAN relationship: regulates CCO:P0001628 ! Rab protein signal transduction [Term] id: CCO:P0001630 name: Ral protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state." [GOC:mah] xref: GO:0032484 is_a: CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:P0001631 name: regulation of Ral protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Ral protein signal transduction." [GOC:mah] xref: GO:0032485 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: regulates CCO:P0001630 ! Ral protein signal transduction [Term] id: CCO:P0001632 name: Rap protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state." [GOC:mah] xref: GO:0032486 is_a: CCO:P0000782 ! Ras protein signal transduction relationship: has_participant CCO:B0002042 ! SGSM3_HUMAN [Term] id: CCO:P0001633 name: regulation of Rap protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Rap protein signal transduction." [GOC:mah] xref: GO:0032487 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: regulates CCO:P0001632 ! Rap protein signal transduction [Term] id: CCO:P0001634 name: Cdc42 protein signal transduction namespace: biological_process def: "A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state." [GOC:mah] xref: GO:0032488 is_a: CCO:P0000783 ! Rho protein signal transduction relationship: has_participant CCO:B0028600 ! APOA1_HUMAN relationship: has_participant CCO:B0034197 ! ABCA1_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0054864 ! APOC3_HUMAN [Term] id: CCO:P0001635 name: regulation of Cdc42 protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction." [GOC:mah] xref: GO:0032489 is_a: CCO:P0001985 ! regulation of Rho protein signal transduction relationship: regulates CCO:P0001634 ! Cdc42 protein signal transduction [Term] id: CCO:P0001636 name: reproduction of a single-celled organism namespace: biological_process def: "The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete] subset: gosubset_prok xref: GO:0032505 is_a: CCO:P0003077 ! cell division [Term] id: CCO:P0001637 name: cytokinetic process namespace: biological_process def: "A cellular process that is involved in the division of the cytoplasm of a cell and its separation into two daughter cells." [GOC:isa_complete, GOC:mah] subset: gosubset_prok xref: GO:0032506 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000453 ! cytokinesis [Term] id: CCO:P0001638 name: regulation of microvillus organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah] xref: GO:0032530 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis [Term] id: CCO:P0001639 name: regulation of follicle cell microvillus organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell." [GOC:mah] xref: GO:0032531 is_a: CCO:P0001638 ! regulation of microvillus organization and biogenesis [Term] id: CCO:P0001640 name: regulation of microvillus length namespace: biological_process def: "A process that modulates the length of a microvillus." [GOC:mah] xref: GO:0032532 is_a: CCO:P0001638 ! regulation of microvillus organization and biogenesis [Term] id: CCO:P0001641 name: regulation of follicle cell microvillus length namespace: biological_process def: "A process that modulates the length of a microvillus on a follicle cell." [GOC:sart, PMID:16260500] xref: GO:0032533 is_a: CCO:P0001639 ! regulation of follicle cell microvillus organization and biogenesis is_a: CCO:P0001640 ! regulation of microvillus length [Term] id: CCO:P0001642 name: regulation of microvillus biogenesis namespace: biological_process def: "A process that modulates the formation of a microvillus." [GOC:mah] xref: GO:0032534 is_a: CCO:P0001638 ! regulation of microvillus organization and biogenesis [Term] id: CCO:P0001643 name: negative regulation of gene-specific transcription namespace: biological_process def: "Any process that stops, prevents or reduces the DNA-dependent transcription of a specific gene or genes." [GOC:mah] synonym: "down regulation of gene-specific transcription" EXACT [] synonym: "down-regulation of gene-specific transcription" EXACT [] synonym: "downregulation of gene-specific transcription" EXACT [] synonym: "inhibition of gene-specific transcription" NARROW [] xref: GO:0032582 is_a: CCO:P0001644 ! regulation of gene-specific transcription is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0054627 ! PEX14_HUMAN [Term] id: CCO:P0001644 name: regulation of gene-specific transcription namespace: biological_process def: "Any process that modulates the DNA-dependent transcription of a specific gene or genes." [GOC:mah] xref: GO:0032583 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001472 ! IGF2_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0032349 ! CELR2_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN [Term] id: CCO:P0001645 name: DNA methylation on adenine namespace: biological_process def: "The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule." [GOC:pf] synonym: "adenine methylation" RELATED [] xref: GO:0032775 is_a: CCO:P0000646 ! DNA methylation [Term] id: CCO:P0001646 name: DNA methylation on cytosine namespace: biological_process def: "The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule." [GOC:pf] synonym: "cytosine methylation" RELATED [] xref: GO:0032776 is_a: CCO:P0000646 ! DNA methylation [Term] id: CCO:P0001647 name: regulation of RNA elongation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides catalyzed by an RNA polymerase." [GOC:mah] synonym: "regulation of transcription elongation" BROAD [] synonym: "regulation of transcriptional elongation" BROAD [] xref: GO:0032784 is_a: CCO:P0003068 ! regulation of RNA metabolic process [Term] id: CCO:P0001648 name: negative regulation of RNA elongation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides catalyzed by an RNA polymerase." [GOC:mah] synonym: "down regulation of RNA elongation" EXACT [] synonym: "down-regulation of RNA elongation" EXACT [] synonym: "downregulation of RNA elongation" EXACT [] synonym: "inhibition of RNA elongation" NARROW [] synonym: "negative regulation of transcription elongation" BROAD [] synonym: "negative regulation of transcriptional elongation" BROAD [] xref: GO:0032785 is_a: CCO:P0001647 ! regulation of RNA elongation is_a: CCO:P0003069 ! negative regulation of RNA metabolic process [Term] id: CCO:P0001649 name: positive regulation of RNA elongation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides catalyzed by an RNA polymerase." [GOC:mah] synonym: "activation of RNA elongation" NARROW [] synonym: "positive regulation of transcription elongation" BROAD [] synonym: "positive regulation of transcriptional elongation" BROAD [] synonym: "stimulation of RNA elongation" NARROW [] synonym: "up regulation of RNA elongation" EXACT [] synonym: "up-regulation of RNA elongation" EXACT [] synonym: "upregulation of RNA elongation" EXACT [] xref: GO:0032786 is_a: CCO:P0001647 ! regulation of RNA elongation is_a: CCO:P0003070 ! positive regulation of RNA metabolic process relationship: has_participant CCO:B0055725 ! ERCC6_HUMAN [Term] id: CCO:P0001650 name: negative regulation of CREB transcription factor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb] synonym: "CREB inhibitor" RELATED [] synonym: "inhibition of CREB transcription factor" EXACT [GOC:dph, GOC:tb] xref: GO:0032792 is_a: CCO:P0002212 ! negative regulation of transcription factor activity relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN [Term] id: CCO:P0001651 name: positive regulation of CREB transcription factor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb] synonym: "activation of CREB" EXACT [] synonym: "activation of CREB transcription factor" EXACT [GOC:dph, GOC:tb] synonym: "CREB activator" RELATED [] xref: GO:0032793 is_a: CCO:P0003022 ! positive regulation of transcription factor activity relationship: has_participant CCO:B0056940 ! TSSK4_HUMAN [Term] id: CCO:P0001652 name: negative regulation of low-density lipoprotein receptor catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors." [GOC:mah] synonym: "down regulation of low-density lipoprotein receptor catabolic process" EXACT [] synonym: "down-regulation of low-density lipoprotein receptor catabolic process" EXACT [] synonym: "downregulation of low-density lipoprotein receptor catabolic process" EXACT [] synonym: "inhibition of low-density lipoprotein receptor catabolic process" NARROW [] synonym: "negative regulation of low-density lipoprotein receptor breakdown" EXACT [] synonym: "negative regulation of low-density lipoprotein receptor catabolism" EXACT [] synonym: "negative regulation of low-density lipoprotein receptor degradation" EXACT [] xref: GO:0032804 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process relationship: has_participant CCO:B0023793 ! FURIN_HUMAN [Term] id: CCO:P0001653 name: positive regulation of low-density lipoprotein receptor catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors." [GOC:mah] synonym: "activation of low-density lipoprotein receptor catabolic process" NARROW [] synonym: "positive regulation of low-density lipoprotein receptor breakdown" EXACT [] synonym: "positive regulation of low-density lipoprotein receptor catabolism" EXACT [] synonym: "positive regulation of low-density lipoprotein receptor degradation" EXACT [] synonym: "stimulation of low-density lipoprotein receptor catabolic process" NARROW [] synonym: "up regulation of low-density lipoprotein receptor catabolic process" EXACT [] synonym: "up-regulation of low-density lipoprotein receptor catabolic process" EXACT [] synonym: "upregulation of low-density lipoprotein receptor catabolic process" EXACT [] xref: GO:0032805 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process [Term] id: CCO:P0001654 name: negative regulation of epinephrine secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of epinephrine." [GOC:vk] synonym: "down regulation of epinephrine secretion" EXACT [] synonym: "down-regulation of epinephrine secretion" EXACT [] synonym: "downregulation of epinephrine secretion" EXACT [] synonym: "inhibition of epinephrine secretion" NARROW [] synonym: "negative regulation of adrenaline secretion" EXACT [] xref: GO:0032811 is_a: CCO:P0001079 ! regulation of epinephrine secretion is_a: CCO:P0001839 ! negative regulation of catecholamine secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0001655 name: positive regulation of epinephrine secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine." [GOC:vk] synonym: "activation of epinephrine secretion" NARROW [] synonym: "positive regulation of adrenaline secretion" EXACT [] synonym: "stimulation of epinephrine secretion" NARROW [] synonym: "up regulation of epinephrine secretion" EXACT [] synonym: "up-regulation of epinephrine secretion" EXACT [] synonym: "upregulation of epinephrine secretion" EXACT [] xref: GO:0032812 is_a: CCO:P0001079 ! regulation of epinephrine secretion is_a: CCO:P0001840 ! positive regulation of catecholamine secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion relationship: has_participant CCO:B0056152 ! CART_HUMAN [Term] id: CCO:P0001656 name: regulation of natural killer cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer cell activation." [GOC:mah] synonym: "regulation of NK cell activation" EXACT [] xref: GO:0032814 is_a: CCO:P0003065 ! regulation of lymphocyte activation [Term] id: CCO:P0001657 name: negative regulation of natural killer cell activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation." [GOC:mah] synonym: "down regulation of natural killer cell activation" EXACT [] synonym: "down-regulation of natural killer cell activation" EXACT [] synonym: "downregulation of natural killer cell activation" EXACT [] synonym: "inhibition of natural killer cell activation" NARROW [] synonym: "negative regulation of NK cell activation" EXACT [] xref: GO:0032815 is_a: CCO:P0001656 ! regulation of natural killer cell activation is_a: CCO:P0003066 ! negative regulation of lymphocyte activation [Term] id: CCO:P0001658 name: positive regulation of natural killer cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer cell activation." [GOC:mah] synonym: "activation of natural killer cell activation" NARROW [] synonym: "positive regulation of NK cell activation" EXACT [] synonym: "stimulation of natural killer cell activation" NARROW [] synonym: "up regulation of natural killer cell activation" EXACT [] synonym: "up-regulation of natural killer cell activation" EXACT [] synonym: "upregulation of natural killer cell activation" EXACT [] xref: GO:0032816 is_a: CCO:P0001656 ! regulation of natural killer cell activation is_a: CCO:P0003067 ! positive regulation of lymphocyte activation relationship: has_participant CCO:B0043824 ! IL12B_HUMAN [Term] id: CCO:P0001659 name: regulation of natural killer cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer cell proliferation." [GOC:mah] synonym: "regulation of NK cell proliferation" EXACT [] xref: GO:0032817 is_a: CCO:P0001656 ! regulation of natural killer cell activation is_a: CCO:P0002914 ! regulation of lymphocyte proliferation relationship: regulates CCO:P0000471 ! natural killer cell proliferation [Term] id: CCO:P0001660 name: negative regulation of natural killer cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation." [GOC:mah] synonym: "down regulation of natural killer cell proliferation" EXACT [] synonym: "down-regulation of natural killer cell proliferation" EXACT [] synonym: "downregulation of natural killer cell proliferation" EXACT [] synonym: "inhibition of natural killer cell proliferation" NARROW [] synonym: "negative regulation of NK cell proliferation" EXACT [] xref: GO:0032818 is_a: CCO:P0001657 ! negative regulation of natural killer cell activation is_a: CCO:P0001659 ! regulation of natural killer cell proliferation is_a: CCO:P0002916 ! negative regulation of lymphocyte proliferation relationship: negatively_regulates CCO:P0000471 ! natural killer cell proliferation [Term] id: CCO:P0001661 name: positive regulation of natural killer cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation." [GOC:mah] synonym: "activation of natural killer cell proliferation" NARROW [] synonym: "positive regulation of NK cell proliferation" EXACT [] synonym: "stimulation of natural killer cell proliferation" NARROW [] synonym: "up regulation of natural killer cell proliferation" EXACT [] synonym: "up-regulation of natural killer cell proliferation" EXACT [] synonym: "upregulation of natural killer cell proliferation" EXACT [] xref: GO:0032819 is_a: CCO:P0001658 ! positive regulation of natural killer cell activation is_a: CCO:P0001659 ! regulation of natural killer cell proliferation is_a: CCO:P0002915 ! positive regulation of lymphocyte proliferation relationship: positively_regulates CCO:P0000471 ! natural killer cell proliferation [Term] id: CCO:P0001662 name: regulation of natural killer cell proliferation during immune response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer cell proliferation during an immune response." [GOC:mah] synonym: "regulation of NK cell proliferation during immune response" EXACT [] xref: GO:0032820 is_a: CCO:P0001659 ! regulation of natural killer cell proliferation relationship: regulates CCO:P0000542 ! natural killer cell proliferation during immune response [Term] id: CCO:P0001663 name: negative regulation of natural killer cell proliferation during immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation during an immune response." [GOC:mah] synonym: "down regulation of natural killer cell proliferation during immune response" EXACT [] synonym: "down-regulation of natural killer cell proliferation during immune response" EXACT [] synonym: "downregulation of natural killer cell proliferation during immune response" EXACT [] synonym: "inhibition of natural killer cell proliferation during immune response" NARROW [] synonym: "negative regulation of NK cell proliferation during immune response" EXACT [] xref: GO:0032821 is_a: CCO:P0001660 ! negative regulation of natural killer cell proliferation is_a: CCO:P0001662 ! regulation of natural killer cell proliferation during immune response relationship: negatively_regulates CCO:P0000542 ! natural killer cell proliferation during immune response [Term] id: CCO:P0001664 name: positive regulation of natural killer cell proliferation during immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation during an immune response." [GOC:mah] synonym: "activation of natural killer cell proliferation during immune response" NARROW [] synonym: "positive regulation of NK cell proliferation during immune response" EXACT [] synonym: "stimulation of natural killer cell proliferation during immune response" NARROW [] synonym: "up regulation of natural killer cell proliferation during immune response" EXACT [] synonym: "up-regulation of natural killer cell proliferation during immune response" EXACT [] synonym: "upregulation of natural killer cell proliferation during immune response" EXACT [] xref: GO:0032822 is_a: CCO:P0001661 ! positive regulation of natural killer cell proliferation is_a: CCO:P0001662 ! regulation of natural killer cell proliferation during immune response relationship: positively_regulates CCO:P0000542 ! natural killer cell proliferation during immune response [Term] id: CCO:P0001665 name: regulation of natural killer cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer cell differentiation." [GOC:mah] synonym: "regulation of NK cell differentiation" EXACT [] xref: GO:0032823 is_a: CCO:P0001656 ! regulation of natural killer cell activation is_a: CCO:P0002433 ! regulation of lymphocyte differentiation [Term] id: CCO:P0001666 name: negative regulation of natural killer cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation." [GOC:mah] synonym: "down regulation of natural killer cell differentiation" EXACT [] synonym: "down-regulation of natural killer cell differentiation" EXACT [] synonym: "downregulation of natural killer cell differentiation" EXACT [] synonym: "inhibition of natural killer cell differentiation" NARROW [] synonym: "negative regulation of NK cell differentiation" EXACT [] xref: GO:0032824 is_a: CCO:P0001657 ! negative regulation of natural killer cell activation is_a: CCO:P0001665 ! regulation of natural killer cell differentiation is_a: CCO:P0002434 ! negative regulation of lymphocyte differentiation [Term] id: CCO:P0001667 name: positive regulation of natural killer cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation." [GOC:mah] synonym: "activation of natural killer cell differentiation" NARROW [] synonym: "positive regulation of NK cell differentiation" EXACT [] synonym: "stimulation of natural killer cell differentiation" NARROW [] synonym: "up regulation of natural killer cell differentiation" EXACT [] synonym: "up-regulation of natural killer cell differentiation" EXACT [] synonym: "upregulation of natural killer cell differentiation" EXACT [] xref: GO:0032825 is_a: CCO:P0001658 ! positive regulation of natural killer cell activation is_a: CCO:P0001665 ! regulation of natural killer cell differentiation is_a: CCO:P0002435 ! positive regulation of lymphocyte differentiation [Term] id: CCO:P0001668 name: regulation of natural killer cell differentiation during immune response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer cell differentiation during an immune response." [GOC:mah] synonym: "regulation of NK cell differentiation during immune response" EXACT [] xref: GO:0032826 is_a: CCO:P0001665 ! regulation of natural killer cell differentiation [Term] id: CCO:P0001669 name: negative regulation of natural killer cell differentiation during immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation during an immune response." [GOC:mah] synonym: "down regulation of natural killer cell differentiation during immune response" EXACT [] synonym: "down-regulation of natural killer cell differentiation during immune response" EXACT [] synonym: "downregulation of natural killer cell differentiation during immune response" EXACT [] synonym: "inhibition of natural killer cell differentiation during immune response" NARROW [] synonym: "negative regulation of NK cell differentiation during immune response" EXACT [] xref: GO:0032827 is_a: CCO:P0001666 ! negative regulation of natural killer cell differentiation is_a: CCO:P0001668 ! regulation of natural killer cell differentiation during immune response [Term] id: CCO:P0001670 name: positive regulation of natural killer cell differentiation during immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation during an immune response." [GOC:mah] synonym: "activation of natural killer cell differentiation during immune response" NARROW [] synonym: "positive regulation of NK cell differentiation during immune response" EXACT [] synonym: "stimulation of natural killer cell differentiation during immune response" NARROW [] synonym: "up regulation of natural killer cell differentiation during immune response" EXACT [] synonym: "up-regulation of natural killer cell differentiation during immune response" EXACT [] synonym: "upregulation of natural killer cell differentiation during immune response" EXACT [] xref: GO:0032828 is_a: CCO:P0001667 ! positive regulation of natural killer cell differentiation is_a: CCO:P0001668 ! regulation of natural killer cell differentiation during immune response [Term] id: CCO:P0001671 name: regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah] synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation" EXACT [] synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] xref: GO:0032829 is_a: CCO:P0002197 ! regulation of CD4-positive, alpha beta T cell differentiation is_a: CCO:P0002403 ! regulation of regulatory T cell differentiation [Term] id: CCO:P0001672 name: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah] synonym: "down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] synonym: "down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] synonym: "downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] synonym: "inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" NARROW [] synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation" EXACT [] synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] xref: GO:0032830 is_a: CCO:P0001671 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation is_a: CCO:P0002198 ! negative regulation of CD4-positive, alpha beta T cell differentiation is_a: CCO:P0002404 ! negative regulation of regulatory T cell differentiation [Term] id: CCO:P0001673 name: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells." [GOC:mah] synonym: "activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" NARROW [] synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation" EXACT [] synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation" EXACT [] synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation" EXACT [] synonym: "stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" NARROW [] synonym: "up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] synonym: "up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] synonym: "upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation" EXACT [] xref: GO:0032831 is_a: CCO:P0001671 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation is_a: CCO:P0002199 ! positive regulation of CD4-positive, alpha beta T cell differentiation is_a: CCO:P0002405 ! positive regulation of regulatory T cell differentiation [Term] id: CCO:P0001674 name: regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells during an immune response." [GOC:mah] synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" EXACT [] synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" EXACT [] synonym: "regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" EXACT [] xref: GO:0032832 is_a: CCO:P0001671 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation [Term] id: CCO:P0001675 name: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells during an immune response." [GOC:mah] synonym: "down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" EXACT [] synonym: "down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" EXACT [] synonym: "downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" EXACT [] synonym: "inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" NARROW [] synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" EXACT [] synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" EXACT [] synonym: "negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" EXACT [] xref: GO:0032833 is_a: CCO:P0001672 ! negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation is_a: CCO:P0001674 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response [Term] id: CCO:P0001676 name: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells during an immune response." [GOC:mah] synonym: "activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" NARROW [] synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response" EXACT [] synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response" EXACT [] synonym: "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response" EXACT [] synonym: "stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" NARROW [] synonym: "up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" EXACT [] synonym: "up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" EXACT [] synonym: "upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response" EXACT [] xref: GO:0032834 is_a: CCO:P0001673 ! positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation is_a: CCO:P0001674 ! regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response [Term] id: CCO:P0001677 name: positive regulation of ARF GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of the GTPase ARF." [GOC:mah] synonym: "stimulation of ARF GTPase activity" NARROW [] synonym: "up regulation of ARF GTPase activity" EXACT [] synonym: "up-regulation of ARF GTPase activity" EXACT [] synonym: "upregulation of ARF GTPase activity" EXACT [] xref: GO:0032850 is_a: CCO:P0001583 ! regulation of ARF GTPase activity is_a: CCO:P0001591 ! positive regulation of Ras GTPase activity [Term] id: CCO:P0001678 name: positive regulation of Rab GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of a GTPase of the Rab family." [GOC:mah] synonym: "stimulation of Rab GTPase activity" NARROW [] synonym: "up regulation of Rab GTPase activity" EXACT [] synonym: "up-regulation of Rab GTPase activity" EXACT [] synonym: "upregulation of Rab GTPase activity" EXACT [] xref: GO:0032851 is_a: CCO:P0001584 ! regulation of Rab GTPase activity is_a: CCO:P0001591 ! positive regulation of Ras GTPase activity [Term] id: CCO:P0001679 name: positive regulation of Ral GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of a GTPase of the Ral family." [GOC:mah] synonym: "stimulation of Ral GTPase activity" NARROW [] synonym: "up regulation of Ral GTPase activity" EXACT [] synonym: "up-regulation of Ral GTPase activity" EXACT [] synonym: "upregulation of Ral GTPase activity" EXACT [] xref: GO:0032852 is_a: CCO:P0001586 ! regulation of Ral GTPase activity is_a: CCO:P0001591 ! positive regulation of Ras GTPase activity [Term] id: CCO:P0001680 name: positive regulation of Ran GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of a GTPase of the Ran family." [GOC:mah] synonym: "stimulation of Ran GTPase activity" NARROW [] synonym: "up regulation of Ran GTPase activity" EXACT [] synonym: "up-regulation of Ran GTPase activity" EXACT [] synonym: "upregulation of Ran GTPase activity" EXACT [] xref: GO:0032853 is_a: CCO:P0001587 ! regulation of Ran GTPase activity is_a: CCO:P0001591 ! positive regulation of Ras GTPase activity [Term] id: CCO:P0001681 name: positive regulation of Rap GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of a GTPase of the Rap family." [GOC:mah] synonym: "stimulation of Rap GTPase activity" NARROW [] synonym: "up regulation of Rap GTPase activity" EXACT [] synonym: "up-regulation of Rap GTPase activity" EXACT [] synonym: "upregulation of Rap GTPase activity" EXACT [] xref: GO:0032854 is_a: CCO:P0001588 ! regulation of Rap GTPase activity is_a: CCO:P0001591 ! positive regulation of Ras GTPase activity [Term] id: CCO:P0001682 name: positive regulation of Rac GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of a GTPase of the Rac family." [GOC:mah] synonym: "stimulation of Rac GTPase activity" NARROW [] synonym: "up regulation of Rac GTPase activity" EXACT [] synonym: "up-regulation of Rac GTPase activity" EXACT [] synonym: "upregulation of Rac GTPase activity" EXACT [] xref: GO:0032855 is_a: CCO:P0001592 ! positive regulation of Rho GTPase activity relationship: has_participant CCO:B0058350 ! ALS2_HUMAN [Term] id: CCO:P0001683 name: activation of Ras GTPase activity namespace: biological_process def: "Any process that initiates the activity of an inactive GTPase of the Ras superfamily through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] comment: Note that this term should not be confused with the molecular function term 'Ras GTPase activator activity ; GO:0005099', which refers specifically to the activity of Ras GAPs. synonym: "Ras GTPase activation" EXACT [] xref: GO:0032856 is_a: CCO:P0001591 ! positive regulation of Ras GTPase activity [Term] id: CCO:P0001684 name: activation of ARF GTPase activity namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme ARF GTPase through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] comment: Note that this term should not be confused with the molecular function term 'ARF GTPase activator activity ; GO:0008060', which refers specifically to the activity of ARF GAPs. synonym: "ARF GTPase activation" EXACT [] xref: GO:0032857 is_a: CCO:P0001677 ! positive regulation of ARF GTPase activity is_a: CCO:P0001683 ! activation of Ras GTPase activity [Term] id: CCO:P0001685 name: activation of Rab GTPase activity namespace: biological_process def: "Any process that initiates the activity of an inactive GTPase of the Rab family through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] comment: Note that this term should not be confused with the molecular function term 'Rab GTPase activator activity ; GO:0005097', which refers specifically to the activity of Rab GAPs. synonym: "Rab GTPase activation" EXACT [] xref: GO:0032858 is_a: CCO:P0001678 ! positive regulation of Rab GTPase activity is_a: CCO:P0001683 ! activation of Ras GTPase activity [Term] id: CCO:P0001686 name: activation of Ral GTPase activity namespace: biological_process def: "Any process that initiates the activity of an inactive GTPase of the Ral family through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] comment: Note that this term should not be confused with the molecular function term 'Ral GTPase activator activity ; GO:0017123', which refers specifically to the activity of Ral GAPs. synonym: "Ral GTPase activation" EXACT [] xref: GO:0032859 is_a: CCO:P0001679 ! positive regulation of Ral GTPase activity is_a: CCO:P0001683 ! activation of Ras GTPase activity [Term] id: CCO:P0001687 name: activation of Ran GTPase activity namespace: biological_process def: "Any process that initiates the activity of an inactive GTPase of the Ran family through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] comment: Note that this term should not be confused with the molecular function term 'Ran GTPase activator activity ; GO:0005098', which refers specifically to the activity of Ran GAPs. synonym: "Ran GTPase activation" EXACT [] xref: GO:0032860 is_a: CCO:P0001680 ! positive regulation of Ran GTPase activity is_a: CCO:P0001683 ! activation of Ras GTPase activity [Term] id: CCO:P0001688 name: activation of Rap GTPase activity namespace: biological_process def: "Any process that initiates the activity of an inactive GTPase of the Rap family through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] comment: Note that this term should not be confused with the molecular function term 'Rap GTPase activator activity ; GO:0046582', which refers specifically to the activity of Rap GAPs. synonym: "Rap GTPase activation" EXACT [] xref: GO:0032861 is_a: CCO:P0001681 ! positive regulation of Rap GTPase activity is_a: CCO:P0001683 ! activation of Ras GTPase activity [Term] id: CCO:P0001689 name: activation of Rho GTPase activity namespace: biological_process def: "Any process that initiates the activity of an inactive GTPase of the Rho family through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] comment: Note that this term should not be confused with the molecular function term 'Rho GTPase activator activity ; GO:0005100', which refers specifically to the activity of Rho GAPs. synonym: "Rho GTPase activation" EXACT [] xref: GO:0032862 is_a: CCO:P0001592 ! positive regulation of Rho GTPase activity is_a: CCO:P0001683 ! activation of Ras GTPase activity relationship: has_participant CCO:B0002014 ! TSC1_HUMAN relationship: has_participant CCO:B0039142 ! FOXJ1_HUMAN relationship: has_participant CCO:B0056649 ! SYDE2_HUMAN relationship: has_participant CCO:B0057088 ! SYDE1_HUMAN [Term] id: CCO:P0001690 name: activation of Rac GTPase activity namespace: biological_process def: "Any process that initiates the activity of an inactive GTPase of the Rac family through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] synonym: "Rac GTPase activation" EXACT [] xref: GO:0032863 is_a: CCO:P0001682 ! positive regulation of Rac GTPase activity is_a: CCO:P0001689 ! activation of Rho GTPase activity relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: has_participant CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:P0001691 name: activation of Cdc42 GTPase activity namespace: biological_process def: "Any process that initiates the activity of the inactive GTPase Cdc42 through the replacement of GDP by GTP." [GOC:mah] synonym: "Cdc42 GTPase activation" EXACT [] xref: GO:0032864 is_a: CCO:P0001689 ! activation of Rho GTPase activity is_a: CCO:P0002157 ! positive regulation of Cdc42 GTPase activity [Term] id: CCO:P0001692 name: regulation of karyogamy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah] xref: GO:0032871 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis [Term] id: CCO:P0001693 name: regulation of stress-activated MAPK cascade namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah] synonym: "regulation of p38 MAPK signaling" EXACT [] synonym: "regulation of p38 MAPK signalling" EXACT [] synonym: "regulation of stress-activated MAPK signaling pathway" EXACT [] synonym: "regulation of stress-activated MAPK signalling pathway" EXACT [] synonym: "regulation of stress-activated MAPKKK cascade" EXACT [] synonym: "regulation of stress-activated MAPKKK signaling pathway" EXACT [] synonym: "regulation of stress-activated MAPKKK signalling pathway" EXACT [] xref: GO:0032872 is_a: CCO:P0002209 ! regulation of MAPKKK cascade relationship: regulates CCO:P0003090 ! stress-activated MAPK cascade [Term] id: CCO:P0001694 name: negative regulation of stress-activated MAPK cascade namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah] synonym: "down regulation of stress-activated MAPK cascade" EXACT [] synonym: "down-regulation of stress-activated MAPK cascade" EXACT [] synonym: "downregulation of stress-activated MAPK cascade" EXACT [] synonym: "inhibition of stress-activated MAPK cascade" NARROW [] synonym: "negative regulation of p38 MAPK signaling" EXACT [] synonym: "negative regulation of p38 MAPK signalling" EXACT [] synonym: "negative regulation of stress-activated MAPK signaling pathway" EXACT [] synonym: "negative regulation of stress-activated MAPK signalling pathway" EXACT [] synonym: "negative regulation of stress-activated MAPKKK cascade" EXACT [] synonym: "negative regulation of stress-activated MAPKKK signaling pathway" EXACT [] synonym: "negative regulation of stress-activated MAPKKK signalling pathway" EXACT [] xref: GO:0032873 is_a: CCO:P0001693 ! regulation of stress-activated MAPK cascade is_a: CCO:P0002210 ! negative regulation of MAPKKK cascade relationship: negatively_regulates CCO:P0003090 ! stress-activated MAPK cascade [Term] id: CCO:P0001695 name: positive regulation of stress-activated MAPK cascade namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." [GOC:mah] synonym: "activation of stress-activated MAPK cascade" NARROW [] synonym: "positive regulation of p38 MAPK signaling" EXACT [] synonym: "positive regulation of p38 MAPK signalling" EXACT [] synonym: "positive regulation of stress-activated MAPK signaling pathway" EXACT [] synonym: "positive regulation of stress-activated MAPK signalling pathway" EXACT [] synonym: "positive regulation of stress-activated MAPKKK cascade" EXACT [] synonym: "positive regulation of stress-activated MAPKKK signaling pathway" EXACT [] synonym: "positive regulation of stress-activated MAPKKK signalling pathway" EXACT [] synonym: "stimulation of stress-activated MAPK cascade" NARROW [] synonym: "up regulation of stress-activated MAPK cascade" EXACT [] synonym: "up-regulation of stress-activated MAPK cascade" EXACT [] synonym: "upregulation of stress-activated MAPK cascade" EXACT [] xref: GO:0032874 is_a: CCO:P0001693 ! regulation of stress-activated MAPK cascade is_a: CCO:P0002211 ! positive regulation of MAPKKK cascade relationship: has_participant CCO:B0058679 ! CARD9_HUMAN relationship: positively_regulates CCO:P0003090 ! stress-activated MAPK cascade [Term] id: CCO:P0001696 name: regulation of DNA endoreduplication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA endoreduplication." [GOC:mah] synonym: "regulation of DNA endoreplication" EXACT [] synonym: "regulation of DNA re-duplication" EXACT [] xref: GO:0032875 is_a: CCO:P0000639 ! regulation of DNA replication relationship: regulates CCO:P0002028 ! DNA endoreduplication [Term] id: CCO:P0001697 name: negative regulation of DNA endoreduplication namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication." [GOC:mah] synonym: "down regulation of DNA endoreduplication" EXACT [] synonym: "down-regulation of DNA endoreduplication" EXACT [] synonym: "downregulation of DNA endoreduplication" EXACT [] synonym: "inhibition of DNA endoreduplication" NARROW [] synonym: "negative regulation of DNA endoreplication" EXACT [] synonym: "negative regulation of DNA re-duplication" EXACT [] xref: GO:0032876 is_a: CCO:P0000813 ! negative regulation of DNA replication is_a: CCO:P0001696 ! regulation of DNA endoreduplication relationship: negatively_regulates CCO:P0002028 ! DNA endoreduplication [Term] id: CCO:P0001698 name: positive regulation of DNA endoreduplication namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA endoreduplication." [GOC:mah] synonym: "activation of DNA endoreduplication" NARROW [] synonym: "positive regulation of DNA endoreplication" EXACT [] synonym: "positive regulation of DNA re-duplication" EXACT [] synonym: "stimulation of DNA endoreduplication" NARROW [] synonym: "up regulation of DNA endoreduplication" EXACT [] synonym: "up-regulation of DNA endoreduplication" EXACT [] synonym: "upregulation of DNA endoreduplication" EXACT [] xref: GO:0032877 is_a: CCO:P0001696 ! regulation of DNA endoreduplication is_a: CCO:P0002528 ! positive regulation of DNA replication relationship: positively_regulates CCO:P0002028 ! DNA endoreduplication [Term] id: CCO:P0001699 name: regulation of establishment and/or maintenance of cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the specification, formation and maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] xref: GO:0032878 is_a: CCO:P0001241 ! regulation of cell morphogenesis [Term] id: CCO:P0001700 name: regulation of chitin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin." [GOC:mah] synonym: "regulation of chitin metabolism" EXACT [] xref: GO:0032882 is_a: CCO:P0001817 ! regulation of amine metabolic process [Term] id: CCO:P0001701 name: regulation of chitin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin." [GOC:mah] synonym: "regulation of chitin anabolism" EXACT [] synonym: "regulation of chitin biosynthes" RELATED [] synonym: "regulation of chitin formation" EXACT [] synonym: "regulation of chitin synthesis" EXACT [] xref: GO:0032883 is_a: CCO:P0001700 ! regulation of chitin metabolic process [Term] id: CCO:P0001702 name: regulation of cell wall chitin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin." [GOC:mah] synonym: "regulation of cell wall chitin anabolism" EXACT [] synonym: "regulation of cell wall chitin biosynthesis" EXACT [] synonym: "regulation of cell wall chitin formation" EXACT [] synonym: "regulation of cell wall chitin synthesis" EXACT [] xref: GO:0032884 is_a: CCO:P0001701 ! regulation of chitin biosynthetic process is_a: CCO:P0001937 ! regulation of cell wall chitin metabolic process [Term] id: CCO:P0001703 name: regulation of microtubule-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah] xref: GO:0032886 is_a: CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001704 name: regulation of vacuole fusion, non-autophagic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole." [GOC:mah] xref: GO:0032889 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis [Term] id: CCO:P0001705 name: negative regulation of viral transcription namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of viral transcription." [GOC:mah] synonym: "down regulation of viral transcription" EXACT [] synonym: "down-regulation of viral transcription" EXACT [] synonym: "downregulation of viral transcription" EXACT [] synonym: "inhibition of viral transcription" NARROW [] xref: GO:0032897 is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent is_a: CCO:P0002738 ! regulation of viral transcription [Term] id: CCO:P0001706 name: neurotrophin production namespace: biological_process def: "The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that block apoptosis in neurons and thus promote nerve growth." [GOC:ecd, GOC:mah, GOC:mtg_mit] xref: GO:0032898 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002233 ! negative regulation of neuron apoptosis [Term] id: CCO:P0001707 name: regulation of neurotrophin production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of production of a neurotrophin." [GOC:mah] xref: GO:0032899 is_a: CCO:U0000002 ! biological process relationship: regulates CCO:P0001706 ! neurotrophin production [Term] id: CCO:P0001708 name: negative regulation of neurotrophin production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin." [GOC:mah] synonym: "down regulation of neurotrophin production" EXACT [] synonym: "down-regulation of neurotrophin production" EXACT [] synonym: "downregulation of neurotrophin production" EXACT [] synonym: "inhibition of neurotrophin production" NARROW [] xref: GO:0032900 is_a: CCO:P0001707 ! regulation of neurotrophin production relationship: negatively_regulates CCO:P0001706 ! neurotrophin production [Term] id: CCO:P0001709 name: positive regulation of neurotrophin production namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin." [GOC:mah] synonym: "activation of neurotrophin production" NARROW [] synonym: "stimulation of neurotrophin production" NARROW [] synonym: "up regulation of neurotrophin production" EXACT [] synonym: "up-regulation of neurotrophin production" EXACT [] synonym: "upregulation of neurotrophin production" EXACT [] xref: GO:0032901 is_a: CCO:P0001707 ! regulation of neurotrophin production relationship: positively_regulates CCO:P0001706 ! neurotrophin production [Term] id: CCO:P0001710 name: nerve growth factor production namespace: biological_process def: "The appearance of nerve growth factor due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels." [GOC:ecd, GOC:mah] synonym: "NGF production" EXACT [] xref: GO:0032902 is_a: CCO:P0001706 ! neurotrophin production relationship: has_participant CCO:B0023793 ! FURIN_HUMAN relationship: has_participant CCO:B0023795 ! PCSK6_HUMAN [Term] id: CCO:P0001711 name: regulation of nerve growth factor production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of production of nerve growth factor." [GOC:mah] synonym: "regulation of NGF production" EXACT [] xref: GO:0032903 is_a: CCO:P0001707 ! regulation of neurotrophin production relationship: regulates CCO:P0001710 ! nerve growth factor production [Term] id: CCO:P0001712 name: negative regulation of nerve growth factor production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor." [GOC:mah] synonym: "down regulation of nerve growth factor production" EXACT [] synonym: "down-regulation of nerve growth factor production" EXACT [] synonym: "downregulation of nerve growth factor production" EXACT [] synonym: "inhibition of nerve growth factor production" NARROW [] synonym: "negative regulation of NGF production" EXACT [] xref: GO:0032904 is_a: CCO:P0001708 ! negative regulation of neurotrophin production is_a: CCO:P0001711 ! regulation of nerve growth factor production relationship: negatively_regulates CCO:P0001710 ! nerve growth factor production [Term] id: CCO:P0001713 name: circadian regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours." [GOC:mah] synonym: "circadian regulation of protein expression" RELATED [] synonym: "diurnal variation of gene expression" RELATED [] synonym: "diurnal variation of protein expression" RELATED [] xref: GO:0032922 is_a: CCO:P0000947 ! regulation of gene expression relationship: has_participant CCO:B0056152 ! CART_HUMAN [Term] id: CCO:P0001714 name: activin receptor signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of any member of the activin family binding to a cell surface receptor." [GOC:rl] synonym: "activin receptor signalling pathway" EXACT [] xref: GO:0032924 is_a: CCO:P0000719 ! transmembrane receptor protein serine/threonine kinase signaling pathway relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: has_participant CCO:B0055940 ! AVR2B_HUMAN relationship: has_participant CCO:B0056834 ! GDF6_HUMAN relationship: has_participant CCO:B0059181 ! GDF2_HUMAN [Term] id: CCO:P0001715 name: regulation of activin receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:rl] synonym: "regulation of activin receptor signalling pathway" EXACT [] synonym: "regulation of activin signaling pathway" RELATED [] synonym: "regulation of activin signalling pathway" RELATED [] xref: GO:0032925 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: regulates CCO:P0001714 ! activin receptor signaling pathway [Term] id: CCO:P0001716 name: negative regulation of activin receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:rl] synonym: "down regulation of activin receptor signaling pathway" EXACT [] synonym: "down-regulation of activin receptor signaling pathway" EXACT [] synonym: "downregulation of activin receptor signaling pathway" EXACT [] synonym: "inhibition of activin receptor signaling pathway" NARROW [] synonym: "negative regulation of activin receptor signalling pathway" EXACT [] synonym: "negative regulation of activin signaling pathway" RELATED [] synonym: "negative regulation of activin signalling pathway" RELATED [] xref: GO:0032926 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001715 ! regulation of activin receptor signaling pathway relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: negatively_regulates CCO:P0001714 ! activin receptor signaling pathway [Term] id: CCO:P0001717 name: positive regulation of activin receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway." [GOC:rl] synonym: "activation of activin receptor signaling pathway" NARROW [] synonym: "positive regulation of activin receptor signalling pathway" EXACT [] synonym: "positive regulation of activin signaling pathway" RELATED [] synonym: "positive regulation of activin signalling pathway" RELATED [] synonym: "stimulation of activin receptor signaling pathway" NARROW [] synonym: "up regulation of activin receptor signaling pathway" EXACT [] synonym: "up-regulation of activin receptor signaling pathway" EXACT [] synonym: "upregulation of activin receptor signaling pathway" EXACT [] xref: GO:0032927 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001715 ! regulation of activin receptor signaling pathway relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN relationship: has_participant CCO:B0055940 ! AVR2B_HUMAN relationship: positively_regulates CCO:P0001714 ! activin receptor signaling pathway [Term] id: CCO:P0001718 name: regulation of superoxide release namespace: biological_process def: "Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah] xref: GO:0032928 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001719 name: negative regulation of superoxide release namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah] synonym: "down regulation of superoxide release" EXACT [] synonym: "down-regulation of superoxide release" EXACT [] synonym: "downregulation of superoxide release" EXACT [] synonym: "inhibition of superoxide release" NARROW [] xref: GO:0032929 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001718 ! regulation of superoxide release [Term] id: CCO:P0001720 name: positive regulation of superoxide release namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell." [GOC:mah] synonym: "activation of superoxide release" NARROW [] synonym: "stimulation of superoxide release" NARROW [] synonym: "up regulation of superoxide release" EXACT [] synonym: "up-regulation of superoxide release" EXACT [] synonym: "upregulation of superoxide release" EXACT [] xref: GO:0032930 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001718 ! regulation of superoxide release [Term] id: CCO:P0001721 name: SREBP-mediated signaling pathway namespace: biological_process def: "A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of altered levels of one or more lipids, and resulting in the activation of transcription by SREBP." [GOC:mah, PMID:12923525] synonym: "SREBP-mediated signalling pathway" EXACT [] xref: GO:0032933 is_a: CCO:P0000685 ! ER-nuclear signaling pathway [Term] id: CCO:P0001722 name: negative regulation of translation in response to oxidative stress namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] xref: GO:0032938 is_a: CCO:P0001533 ! negative regulation of translation in response to stress is_a: CCO:P0002241 ! regulation of translation in response to oxidative stress [Term] id: CCO:P0001723 name: positive regulation of translation in response to oxidative stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:mah] synonym: "activation of translation in response to oxidative stress" NARROW [] synonym: "stimulation of translation in response to oxidative stress" NARROW [] synonym: "up regulation of translation in response to oxidative stress" EXACT [] synonym: "up-regulation of translation in response to oxidative stress" EXACT [] synonym: "upregulation of translation in response to oxidative stress" EXACT [] xref: GO:0032939 is_a: CCO:P0001534 ! positive regulation of translation in response to stress is_a: CCO:P0002241 ! regulation of translation in response to oxidative stress [Term] id: CCO:P0001724 name: mononuclear cell proliferation namespace: biological_process def: "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] synonym: "PBMC proliferation" NARROW [] synonym: "peripheral blood mononuclear cell proliferation" NARROW [] xref: GO:0032943 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0055006 ! ACE_HUMAN [Term] id: CCO:P0001725 name: regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "regulation of PBMC proliferation" NARROW [] synonym: "regulation of peripheral blood mononuclear cell proliferation" NARROW [] xref: GO:0032944 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0001724 ! mononuclear cell proliferation [Term] id: CCO:P0001726 name: negative regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "negative regulation of PBMC proliferation" NARROW [] synonym: "negative regulation of peripheral blood mononuclear cell proliferation" NARROW [] xref: GO:0032945 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0001725 ! regulation of mononuclear cell proliferation relationship: negatively_regulates CCO:P0001724 ! mononuclear cell proliferation [Term] id: CCO:P0001727 name: positive regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "activation of mononuclear cell proliferation" NARROW [] synonym: "positive regulation of PBMC proliferation" NARROW [] synonym: "positive regulation of peripheral blood mononuclear cell proliferation" NARROW [] synonym: "stimulation of mononuclear cell proliferation" NARROW [] synonym: "up regulation of mononuclear cell proliferation" EXACT [] synonym: "up-regulation of mononuclear cell proliferation" EXACT [] synonym: "upregulation of mononuclear cell proliferation" EXACT [] xref: GO:0032946 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0001725 ! regulation of mononuclear cell proliferation relationship: positively_regulates CCO:P0001724 ! mononuclear cell proliferation [Term] id: CCO:P0001728 name: regulation of alpha-glucan metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans." [GOC:mah] subset: gosubset_prok synonym: "regulation of alpha-glucan metabolism" EXACT [] xref: GO:0032948 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001729 name: regulation of alpha-glucan biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans." [GOC:mah] synonym: "regulation of alpha-glucan anabolism" EXACT [] synonym: "regulation of alpha-glucan biosynthesis" EXACT [] synonym: "regulation of alpha-glucan formation" EXACT [] synonym: "regulation of alpha-glucan synthesis" EXACT [] xref: GO:0032949 is_a: CCO:P0001728 ! regulation of alpha-glucan metabolic process [Term] id: CCO:P0001730 name: regulation of beta-glucan metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans." [GOC:mah] subset: gosubset_prok synonym: "regulation of beta-glucan metabolism" EXACT [] xref: GO:0032950 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001731 name: regulation of beta-glucan biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans." [GOC:mah] synonym: "regulation of beta-glucan anabolism" EXACT [] synonym: "regulation of beta-glucan biosynthesis" EXACT [] synonym: "regulation of beta-glucan formation" EXACT [] synonym: "regulation of beta-glucan synthesis" EXACT [] xref: GO:0032951 is_a: CCO:P0001730 ! regulation of beta-glucan metabolic process [Term] id: CCO:P0001732 name: regulation of 1,3-beta-glucan metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-1,3 glucans." [GOC:mah] subset: gosubset_prok synonym: "regulation of 1,3-beta-glucan metabolism" EXACT [] xref: GO:0032952 is_a: CCO:P0001730 ! regulation of beta-glucan metabolic process [Term] id: CCO:P0001733 name: regulation of 1,3-beta-glucan biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-1,3 glucans." [GOC:mah] synonym: "regulation of 1,3-beta-glucan anabolism" EXACT [] synonym: "regulation of 1,3-beta-glucan biosynthesis" EXACT [] synonym: "regulation of 1,3-beta-glucan formation" EXACT [] synonym: "regulation of 1,3-beta-glucan synthesis" EXACT [] xref: GO:0032953 is_a: CCO:P0001731 ! regulation of beta-glucan biosynthetic process is_a: CCO:P0001732 ! regulation of 1,3-beta-glucan metabolic process [Term] id: CCO:P0001734 name: regulation of cytokinetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a cytokinetic process." [GOC:mah] subset: gosubset_prok xref: GO:0032954 is_a: CCO:P0002955 ! regulation of cellular process relationship: regulates CCO:P0001637 ! cytokinetic process [Term] id: CCO:P0001735 name: regulation of barrier septum formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of barrier septum formation." [GOC:mah] xref: GO:0032955 is_a: CCO:P0001734 ! regulation of cytokinetic process relationship: regulates CCO:P0000454 ! barrier septum formation [Term] id: CCO:P0001736 name: regulation of actin cytoskeleton organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah] xref: GO:0032956 is_a: CCO:P0001744 ! regulation of actin filament-based process relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0056278 ! GRDN_HUMAN [Term] id: CCO:P0001737 name: regulation of inositol trisphosphate biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate." [GOC:mah] synonym: "regulation of inositol trisphosphate anabolism" EXACT [] synonym: "regulation of inositol trisphosphate biosynthesis" EXACT [] synonym: "regulation of inositol trisphosphate formation" EXACT [] synonym: "regulation of inositol trisphosphate synthesis" EXACT [] synonym: "regulation of IP3 biosynthesis" EXACT [] synonym: "regulation of IP3 biosynthetic process" EXACT [] synonym: "regulation of myo-inositol trisphosphate biosynthesis" NARROW [] synonym: "regulation of myo-inositol trisphosphate biosynthetic process" NARROW [] xref: GO:0032960 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0001738 name: negative regulation of inositol trisphosphate biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate." [GOC:mah] synonym: "negative regulation of inositol trisphosphate anabolism" EXACT [] synonym: "negative regulation of inositol trisphosphate biosynthesis" EXACT [] synonym: "negative regulation of inositol trisphosphate formation" EXACT [] synonym: "negative regulation of inositol trisphosphate synthesis" EXACT [] synonym: "negative regulation of IP3 biosynthesis" EXACT [] synonym: "negative regulation of IP3 biosynthetic process" EXACT [] synonym: "negative regulation of myo-inositol trisphosphate biosynthesis" NARROW [] synonym: "negative regulation of myo-inositol trisphosphate biosynthetic process" NARROW [] xref: GO:0032961 is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0001737 ! regulation of inositol trisphosphate biosynthetic process [Term] id: CCO:P0001739 name: positive regulation of inositol trisphosphate biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate." [GOC:mah] synonym: "positive regulation of inositol trisphosphate anabolism" EXACT [] synonym: "positive regulation of inositol trisphosphate biosynthesis" EXACT [] synonym: "positive regulation of inositol trisphosphate formation" EXACT [] synonym: "positive regulation of inositol trisphosphate synthesis" EXACT [] synonym: "positive regulation of IP3 biosynthesis" EXACT [] synonym: "positive regulation of IP3 biosynthetic process" EXACT [] synonym: "positive regulation of myo-inositol trisphosphate biosynthesis" NARROW [] synonym: "positive regulation of myo-inositol trisphosphate biosynthetic process" NARROW [] xref: GO:0032962 is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0001737 ! regulation of inositol trisphosphate biosynthetic process [Term] id: CCO:P0001740 name: regulation of collagen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "regulation of collagen anabolism" EXACT [] synonym: "regulation of collagen biosynthesis" EXACT [] synonym: "regulation of collagen formation" EXACT [] synonym: "regulation of collagen synthesis" EXACT [] xref: GO:0032965 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0001741 name: negative regulation of collagen biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "negative regulation of collagen anabolism" EXACT [] synonym: "negative regulation of collagen biosynthesis" EXACT [] synonym: "negative regulation of collagen formation" EXACT [] synonym: "negative regulation of collagen synthesis" EXACT [] xref: GO:0032966 is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0001740 ! regulation of collagen biosynthetic process [Term] id: CCO:P0001742 name: positive regulation of collagen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "positive regulation of collagen anabolism" EXACT [] synonym: "positive regulation of collagen biosynthesis" EXACT [] synonym: "positive regulation of collagen formation" EXACT [] synonym: "positive regulation of collagen synthesis" EXACT [] xref: GO:0032967 is_a: CCO:P0001740 ! regulation of collagen biosynthetic process is_a: CCO:P0002524 ! positive regulation of translation relationship: has_participant CCO:B0001464 ! THRB_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN [Term] id: CCO:P0001743 name: positive regulation of RNA elongation from RNA polymerase II promoter namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides, catalyzed by RNA polymerase II." [GOC:mah] synonym: "positive regulation of transcription elongation from RNA polymerase II promoter" BROAD [] xref: GO:0032968 is_a: CCO:P0001649 ! positive regulation of RNA elongation is_a: CCO:P0001946 ! regulation of RNA elongation from RNA polymerase II promoter [Term] id: CCO:P0001744 name: regulation of actin filament-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah] xref: GO:0032970 is_a: CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0001745 name: regulation of muscle filament sliding namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle filament sliding." [GOC:ecd] xref: GO:0032971 is_a: CCO:P0001744 ! regulation of actin filament-based process relationship: has_participant CCO:B0036526 ! MYLK2_HUMAN relationship: has_participant CCO:B0056023 ! MYPC3_HUMAN [Term] id: CCO:P0001746 name: regulation of muscle filament sliding speed namespace: biological_process def: "Any process that modulates the velocity of muscle filament sliding." [GOC:dph, GOC:ecd, GOC:tb] xref: GO:0032972 is_a: CCO:P0001745 ! regulation of muscle filament sliding relationship: has_participant CCO:B0055634 ! TNNC1_HUMAN [Term] id: CCO:P0001747 name: release of matrix enzymes from mitochondria namespace: biological_process def: "The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol." [GOC:mah, PMID:9843949] synonym: "mAST release from mitochondria" NARROW [] synonym: "release of aspartate aminotransferase from mitochondria" NARROW [] xref: GO:0032976 is_a: CCO:P0000844 ! apoptotic mitochondrial changes [Term] id: CCO:P0001748 name: regulation of fungal-type cell wall biogenesis namespace: biological_process def: "Any process that modulates the chemical reactions and pathways resulting in the formation of the fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of chitin- and beta-glucan-containing cell wall biogenesis" EXACT [] xref: GO:0032995 is_a: CCO:P0003291 ! regulation of fungal-type cell wall organization and biogenesis [Term] id: CCO:P0001749 name: muscle cell proliferation namespace: biological_process def: "The expansion of a muscle cell population by cell division." [CL:0000187, GOC:mah] synonym: "myocyte proliferation" EXACT [] xref: GO:0033002 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001750 name: regulation of mast cell activation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of mast cell activation." [GOC:mah] xref: GO:0033003 is_a: CCO:P0000562 ! regulation of leukocyte activation [Term] id: CCO:P0001751 name: negative regulation of mast cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of mast cell activation." [GOC:mah] xref: GO:0033004 is_a: CCO:P0000563 ! negative regulation of leukocyte activation is_a: CCO:P0001750 ! regulation of mast cell activation [Term] id: CCO:P0001752 name: positive regulation of mast cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of mast cell activation." [GOC:mah] xref: GO:0033005 is_a: CCO:P0000564 ! positive regulation of leukocyte activation is_a: CCO:P0001750 ! regulation of mast cell activation [Term] id: CCO:P0001753 name: regulation of mast cell activation during immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of mast cell activation during an immune response." [GOC:mah] xref: GO:0033006 is_a: CCO:P0001750 ! regulation of mast cell activation [Term] id: CCO:P0001754 name: negative regulation of mast cell activation during immune response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of mast cell activation during an immune response." [GOC:mah] xref: GO:0033007 is_a: CCO:P0001751 ! negative regulation of mast cell activation is_a: CCO:P0001753 ! regulation of mast cell activation during immune response [Term] id: CCO:P0001755 name: positive regulation of mast cell activation during immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of mast cell activation during an immune response." [GOC:mah] xref: GO:0033008 is_a: CCO:P0001752 ! positive regulation of mast cell activation is_a: CCO:P0001753 ! regulation of mast cell activation during immune response [Term] id: CCO:P0001756 name: regulation of mast cell apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of mast cell apoptosis." [GOC:add] xref: GO:0033025 is_a: CCO:P0001762 ! regulation of myeloid cell apoptosis [Term] id: CCO:P0001757 name: negative regulation of mast cell apoptosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a mast cell apoptosis." [GOC:add] synonym: "down regulation of mast cell apoptosis" EXACT [] synonym: "down-regulation of mast cell apoptosis" EXACT [] synonym: "downregulation of mast cell apoptosis" EXACT [] synonym: "inhibition of mast cell apoptosis" NARROW [] xref: GO:0033026 is_a: CCO:P0001756 ! regulation of mast cell apoptosis is_a: CCO:P0001763 ! negative regulation of myeloid cell apoptosis relationship: has_participant CCO:B0055217 ! FCERG_HUMAN [Term] id: CCO:P0001758 name: positive regulation of mast cell apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of mast cell apoptosis." [GOC:add] synonym: "activation of mast cell apoptosis" NARROW [] synonym: "stimulation of mast cell apoptosis" NARROW [] synonym: "up regulation of mast cell apoptosis" EXACT [] synonym: "up-regulation of mast cell apoptosis" EXACT [] synonym: "upregulation of mast cell apoptosis" EXACT [] xref: GO:0033027 is_a: CCO:P0001756 ! regulation of mast cell apoptosis is_a: CCO:P0001764 ! positive regulation of myeloid cell apoptosis [Term] id: CCO:P0001759 name: regulation of neutrophil apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of neutrophil apoptosis." [GOC:add] xref: GO:0033029 is_a: CCO:P0001762 ! regulation of myeloid cell apoptosis [Term] id: CCO:P0001760 name: negative regulation of neutrophil apoptosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a neutrophil apoptosis." [GOC:add] synonym: "down regulation of neutrophil apoptosis" EXACT [] synonym: "down-regulation of neutrophil apoptosis" EXACT [] synonym: "downregulation of neutrophil apoptosis" EXACT [] synonym: "inhibition of neutrophil apoptosis" NARROW [] xref: GO:0033030 is_a: CCO:P0001759 ! regulation of neutrophil apoptosis is_a: CCO:P0001763 ! negative regulation of myeloid cell apoptosis [Term] id: CCO:P0001761 name: positive regulation of neutrophil apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of neutrophil apoptosis." [GOC:add] synonym: "activation of neutrophil apoptosis" NARROW [] synonym: "stimulation of neutrophil apoptosis" NARROW [] synonym: "up regulation of neutrophil apoptosis" EXACT [] synonym: "up-regulation of neutrophil apoptosis" EXACT [] synonym: "upregulation of neutrophil apoptosis" EXACT [] xref: GO:0033031 is_a: CCO:P0001759 ! regulation of neutrophil apoptosis is_a: CCO:P0001764 ! positive regulation of myeloid cell apoptosis [Term] id: CCO:P0001762 name: regulation of myeloid cell apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid cell apoptosis." [GOC:add] xref: GO:0033032 is_a: CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:P0001763 name: negative regulation of myeloid cell apoptosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptosis." [GOC:add] synonym: "down regulation of myeloid cell apoptosis" EXACT [] synonym: "down-regulation of myeloid cell apoptosis" EXACT [] synonym: "downregulation of myeloid cell apoptosis" EXACT [] synonym: "inhibition of myeloid cell apoptosis" NARROW [] xref: GO:0033033 is_a: CCO:P0001762 ! regulation of myeloid cell apoptosis is_a: CCO:P0002148 ! negative regulation of apoptosis relationship: has_participant CCO:B0001930 ! MAEA_HUMAN relationship: has_participant CCO:B0054871 ! APOH_HUMAN [Term] id: CCO:P0001764 name: positive regulation of myeloid cell apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptosis." [GOC:add] synonym: "activation of myeloid cell apoptosis" NARROW [] synonym: "stimulation of myeloid cell apoptosis" NARROW [] synonym: "up regulation of myeloid cell apoptosis" EXACT [] synonym: "up-regulation of myeloid cell apoptosis" EXACT [] synonym: "upregulation of myeloid cell apoptosis" EXACT [] xref: GO:0033034 is_a: CCO:P0001762 ! regulation of myeloid cell apoptosis is_a: CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:P0001765 name: regulation of organelle organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah] xref: GO:0033043 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0001766 name: regulation of chromosome organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." [GOC:mah] xref: GO:0033044 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis [Term] id: CCO:P0001767 name: immature T cell proliferation namespace: biological_process def: "The expansion of an immature T cell population by cell division." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] xref: GO:0033079 is_a: CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0001768 name: immature T cell proliferation in the thymus namespace: biological_process def: "The expansion of an immature T cell population by cell division in the thymus." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "thymic T cell proliferation" EXACT [] synonym: "thymocyte cell proliferation" EXACT [] synonym: "thymocyte proliferation" EXACT [] xref: GO:0033080 is_a: CCO:P0001767 ! immature T cell proliferation [Term] id: CCO:P0001769 name: regulation of T cell differentiation in the thymus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus." [GOC:add, GOC:mah] synonym: "regulation of thymic T cell differentiation" EXACT [] synonym: "regulation of thymocyte cell differentiation" EXACT [] synonym: "regulation of thymocyte differentiation" EXACT [] xref: GO:0033081 is_a: CCO:P0002394 ! regulation of T cell differentiation relationship: has_participant CCO:B0033014 ! SODC_HUMAN relationship: has_participant CCO:B0051232 ! CLPT1_HUMAN [Term] id: CCO:P0001770 name: regulation of extrathymic T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation." [GOC:add, GOC:mah] xref: GO:0033082 is_a: CCO:P0002394 ! regulation of T cell differentiation [Term] id: CCO:P0001771 name: regulation of immature T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of immature T cell proliferation." [GOC:add, GOC:mah] xref: GO:0033083 is_a: CCO:P0002046 ! regulation of T cell proliferation relationship: regulates CCO:P0001767 ! immature T cell proliferation [Term] id: CCO:P0001772 name: regulation of immature T cell proliferation in the thymus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus." [GOC:add, GOC:mah] synonym: "regulation of thymic T cell proliferation" EXACT [] synonym: "regulation of thymocyte cell proliferation" EXACT [] synonym: "regulation of thymocyte proliferation" EXACT [] xref: GO:0033084 is_a: CCO:P0001771 ! regulation of immature T cell proliferation relationship: regulates CCO:P0001768 ! immature T cell proliferation in the thymus [Term] id: CCO:P0001773 name: negative regulation of T cell differentiation in the thymus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus." [GOC:add, GOC:mah] synonym: "negative regulation of thymic T cell differentiation" EXACT [] synonym: "negative regulation of thymocyte cell differentiation" EXACT [] synonym: "negative regulation of thymocyte differentiation" EXACT [] xref: GO:0033085 is_a: CCO:P0001769 ! regulation of T cell differentiation in the thymus is_a: CCO:P0002395 ! negative regulation of T cell differentiation relationship: has_participant CCO:B0039142 ! FOXJ1_HUMAN [Term] id: CCO:P0001774 name: negative regulation of extrathymic T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extrathymic T cell differentiation." [GOC:add, GOC:mah] xref: GO:0033086 is_a: CCO:P0001770 ! regulation of extrathymic T cell differentiation is_a: CCO:P0002395 ! negative regulation of T cell differentiation [Term] id: CCO:P0001775 name: negative regulation of immature T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of immature T cell proliferation." [GOC:add, GOC:mah] xref: GO:0033087 is_a: CCO:P0001771 ! regulation of immature T cell proliferation is_a: CCO:P0002047 ! negative regulation of T cell proliferation relationship: negatively_regulates CCO:P0001767 ! immature T cell proliferation [Term] id: CCO:P0001776 name: negative regulation of immature T cell proliferation in the thymus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of immature T cell proliferation in the thymus." [GOC:add, GOC:mah] synonym: "negative regulation of thymic T cell proliferation" EXACT [] synonym: "negative regulation of thymocyte cell proliferation" EXACT [] synonym: "negative regulation of thymocyte proliferation" EXACT [] xref: GO:0033088 is_a: CCO:P0001772 ! regulation of immature T cell proliferation in the thymus is_a: CCO:P0001775 ! negative regulation of immature T cell proliferation relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: negatively_regulates CCO:P0001768 ! immature T cell proliferation in the thymus [Term] id: CCO:P0001777 name: positive regulation of T cell differentiation in the thymus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus." [GOC:add, GOC:mah] synonym: "positive regulation of thymic T cell differentiation" EXACT [] synonym: "positive regulation of thymocyte cell differentiation" EXACT [] synonym: "positive regulation of thymocyte differentiation" EXACT [] xref: GO:0033089 is_a: CCO:P0001769 ! regulation of T cell differentiation in the thymus is_a: CCO:P0002396 ! positive regulation of T cell differentiation relationship: has_participant CCO:B0054768 ! VNN1_HUMAN [Term] id: CCO:P0001778 name: positive regulation of extrathymic T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation." [GOC:add, GOC:mah] xref: GO:0033090 is_a: CCO:P0001770 ! regulation of extrathymic T cell differentiation is_a: CCO:P0002396 ! positive regulation of T cell differentiation [Term] id: CCO:P0001779 name: positive regulation of immature T cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of immature T cell proliferation." [GOC:add, GOC:mah] xref: GO:0033091 is_a: CCO:P0001771 ! regulation of immature T cell proliferation is_a: CCO:P0002041 ! positive regulation of T cell proliferation relationship: positively_regulates CCO:P0001767 ! immature T cell proliferation [Term] id: CCO:P0001780 name: positive regulation of immature T cell proliferation in the thymus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus." [GOC:add, GOC:mah] synonym: "positive regulation of thymic T cell proliferation" EXACT [] synonym: "positive regulation of thymocyte cell proliferation" EXACT [] synonym: "positive regulation of thymocyte proliferation" EXACT [] xref: GO:0033092 is_a: CCO:P0001772 ! regulation of immature T cell proliferation in the thymus is_a: CCO:P0001779 ! positive regulation of immature T cell proliferation relationship: positively_regulates CCO:P0001768 ! immature T cell proliferation in the thymus [Term] id: CCO:P0001781 name: negative regulation of RNA splicing namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA splicing." [GOC:mah] xref: GO:0033119 is_a: CCO:P0002221 ! regulation of RNA splicing is_a: CCO:P0003069 ! negative regulation of RNA metabolic process [Term] id: CCO:P0001782 name: positive regulation of RNA splicing namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of RNA splicing." [GOC:mah] xref: GO:0033120 is_a: CCO:P0002221 ! regulation of RNA splicing is_a: CCO:P0003070 ! positive regulation of RNA metabolic process [Term] id: CCO:P0001783 name: regulation of purine nucleotide catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides." [GOC:mah] synonym: "regulation of purine nucleotide breakdown" EXACT [] synonym: "regulation of purine nucleotide catabolism" EXACT [] synonym: "regulation of purine nucleotide degradation" EXACT [] xref: GO:0033121 is_a: CCO:P0001304 ! regulation of nucleotide catabolic process [Term] id: CCO:P0001784 name: negative regulation of purine nucleotide catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides." [GOC:mah] synonym: "negative regulation of purine nucleotide breakdown" EXACT [] synonym: "negative regulation of purine nucleotide catabolism" EXACT [] synonym: "negative regulation of purine nucleotide degradation" EXACT [] xref: GO:0033122 is_a: CCO:P0001305 ! negative regulation of nucleotide catabolic process is_a: CCO:P0001783 ! regulation of purine nucleotide catabolic process [Term] id: CCO:P0001785 name: positive regulation of purine nucleotide catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides." [GOC:mah] synonym: "positive regulation of purine nucleotide breakdown" EXACT [] synonym: "positive regulation of purine nucleotide catabolism" EXACT [] synonym: "positive regulation of purine nucleotide degradation" EXACT [] xref: GO:0033123 is_a: CCO:P0001306 ! positive regulation of nucleotide catabolic process is_a: CCO:P0001783 ! regulation of purine nucleotide catabolic process [Term] id: CCO:P0001786 name: regulation of GTP catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [GOC:mah] synonym: "regulation of GTP breakdown" EXACT [] synonym: "regulation of GTP catabolism" EXACT [] synonym: "regulation of GTP degradation" EXACT [] xref: GO:0033124 is_a: CCO:P0001783 ! regulation of purine nucleotide catabolic process [Term] id: CCO:P0001787 name: negative regulation of GTP catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [GOC:mah] synonym: "negative regulation of GTP breakdown" EXACT [] synonym: "negative regulation of GTP catabolism" EXACT [] synonym: "negative regulation of GTP degradation" EXACT [] xref: GO:0033125 is_a: CCO:P0001784 ! negative regulation of purine nucleotide catabolic process is_a: CCO:P0001786 ! regulation of GTP catabolic process [Term] id: CCO:P0001788 name: positive regulation of GTP catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [GOC:mah] synonym: "positive regulation of GTP breakdown" EXACT [] synonym: "positive regulation of GTP catabolism" EXACT [] synonym: "positive regulation of GTP degradation" EXACT [] xref: GO:0033126 is_a: CCO:P0001785 ! positive regulation of purine nucleotide catabolic process is_a: CCO:P0001786 ! regulation of GTP catabolic process [Term] id: CCO:P0001789 name: regulation of histone phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein." [GOC:mah] xref: GO:0033127 is_a: CCO:P0000500 ! regulation of protein amino acid phosphorylation is_a: CCO:P0001367 ! regulation of histone modification [Term] id: CCO:P0001790 name: negative regulation of histone phosphorylation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein." [GOC:mah] xref: GO:0033128 is_a: CCO:P0000501 ! negative regulation of protein amino acid phosphorylation is_a: CCO:P0001368 ! negative regulation of histone modification is_a: CCO:P0001789 ! regulation of histone phosphorylation [Term] id: CCO:P0001791 name: positive regulation of histone phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein." [GOC:mah] xref: GO:0033129 is_a: CCO:P0000502 ! positive regulation of protein amino acid phosphorylation is_a: CCO:P0001369 ! positive regulation of histone modification is_a: CCO:P0001789 ! regulation of histone phosphorylation [Term] id: CCO:P0001792 name: regulation of peptidyl-serine phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] subset: gosubset_prok xref: GO:0033135 is_a: CCO:P0000500 ! regulation of protein amino acid phosphorylation [Term] id: CCO:P0001793 name: serine phosphorylation of STAT3 protein namespace: biological_process def: "The process of introducing a phosphate group to a serine residue of the STAT3 protein." [GOC:jl, GOC:mah] xref: GO:0033136 is_a: CCO:P0002066 ! serine phosphorylation of STAT protein [Term] id: CCO:P0001794 name: negative regulation of peptidyl-serine phosphorylation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] xref: GO:0033137 is_a: CCO:P0000501 ! negative regulation of protein amino acid phosphorylation is_a: CCO:P0001792 ! regulation of peptidyl-serine phosphorylation [Term] id: CCO:P0001795 name: positive regulation of peptidyl-serine phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] xref: GO:0033138 is_a: CCO:P0000502 ! positive regulation of protein amino acid phosphorylation is_a: CCO:P0001792 ! regulation of peptidyl-serine phosphorylation relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN relationship: has_participant CCO:B0055126 ! IL11_HUMAN relationship: has_participant CCO:B0058300 ! DOCK7_HUMAN [Term] id: CCO:P0001796 name: regulation of peptidyl-serine phosphorylation of STAT protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] subset: gosubset_prok xref: GO:0033139 is_a: CCO:P0001792 ! regulation of peptidyl-serine phosphorylation relationship: part_of CCO:P0002066 ! serine phosphorylation of STAT protein [Term] id: CCO:P0001797 name: negative regulation of peptidyl-serine phosphorylation of STAT protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] subset: gosubset_prok xref: GO:0033140 is_a: CCO:P0001794 ! negative regulation of peptidyl-serine phosphorylation is_a: CCO:P0001796 ! regulation of peptidyl-serine phosphorylation of STAT protein [Term] id: CCO:P0001798 name: positive regulation of peptidyl-serine phosphorylation of STAT protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] subset: gosubset_prok xref: GO:0033141 is_a: CCO:P0001795 ! positive regulation of peptidyl-serine phosphorylation is_a: CCO:P0001796 ! regulation of peptidyl-serine phosphorylation of STAT protein [Term] id: CCO:P0001799 name: regulation of steroid hormone receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway." [GOC:mah] synonym: "regulation of steroid hormone receptor signalling pathway" EXACT [] xref: GO:0033143 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0054853 ! IGF1A_HUMAN relationship: regulates CCO:P0001278 ! steroid hormone receptor signaling pathway [Term] id: CCO:P0001800 name: negative regulation of steroid hormone receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway." [GOC:mah] synonym: "negative regulation of steroid hormone receptor signalling pathway" EXACT [] xref: GO:0033144 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001799 ! regulation of steroid hormone receptor signaling pathway relationship: has_participant CCO:B0055483 ! NR0B1_HUMAN relationship: negatively_regulates CCO:P0001278 ! steroid hormone receptor signaling pathway [Term] id: CCO:P0001801 name: positive regulation of steroid hormone receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway." [GOC:mah] synonym: "positive regulation of steroid hormone receptor signalling pathway" EXACT [] xref: GO:0033145 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001799 ! regulation of steroid hormone receptor signaling pathway relationship: positively_regulates CCO:P0001278 ! steroid hormone receptor signaling pathway [Term] id: CCO:P0001802 name: regulation of estrogen receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of an estrogen receptor signaling pathway." [GOC:mah] synonym: "regulation of estrogen receptor signalling pathway" EXACT [] xref: GO:0033146 is_a: CCO:P0001799 ! regulation of steroid hormone receptor signaling pathway relationship: regulates CCO:P0001279 ! estrogen receptor signaling pathway [Term] id: CCO:P0001803 name: negative regulation of estrogen receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an estrogen receptor signaling pathway." [GOC:mah] synonym: "negative regulation of estrogen receptor signalling pathway" EXACT [] xref: GO:0033147 is_a: CCO:P0001800 ! negative regulation of steroid hormone receptor signaling pathway is_a: CCO:P0001802 ! regulation of estrogen receptor signaling pathway relationship: negatively_regulates CCO:P0001279 ! estrogen receptor signaling pathway [Term] id: CCO:P0001804 name: positive regulation of estrogen receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of an estrogen receptor signaling pathway." [GOC:mah] synonym: "positive regulation of estrogen receptor signalling pathway" EXACT [] xref: GO:0033148 is_a: CCO:P0001801 ! positive regulation of steroid hormone receptor signaling pathway is_a: CCO:P0001802 ! regulation of estrogen receptor signaling pathway relationship: positively_regulates CCO:P0001279 ! estrogen receptor signaling pathway [Term] id: CCO:P0001805 name: RNA interference, conversion of ds siRNA to ss siRNA namespace: biological_process def: "The process by which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference." [GOC:mah, PMID:17310250] xref: GO:0033168 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001260 ! RNA interference, production of siRNA [Term] id: CCO:P0001806 name: calcineurin-NFAT signaling pathway namespace: biological_process def: "A series of molecular signals that results in activation of transcription by a member of the NFAT protein family as a consequence of NFAT dephosphorylation by activated calcineurin. The signaling is generated by a receptor binding a ligand, followed by activation of phospholipase C and the subsequent release of inositol trisphosphate, which in turn leads to an increase in intracellular calcium ion concentration that mediates the activation of calcineurin." [GOC:lm, GOC:mah, PMID:15928679] synonym: "calcineurin-NFAT signalling pathway" EXACT [] xref: GO:0033173 is_a: CCO:P0001145 ! calcium-mediated signaling is_a: CCO:P0002762 ! inositol phosphate-mediated signaling [Term] id: CCO:P0001807 name: regulation of histone ubiquitination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the addition of a ubiquitin moiety to a histone protein." [GOC:mah] xref: GO:0033182 is_a: CCO:P0001367 ! regulation of histone modification is_a: CCO:P0001430 ! regulation of protein ubiquitination relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN [Term] id: CCO:P0001808 name: negative regulation of histone ubiquitination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the addition of a ubiquitin moiety to a histone protein." [GOC:mah] xref: GO:0033183 is_a: CCO:P0001368 ! negative regulation of histone modification is_a: CCO:P0001431 ! negative regulation of protein ubiquitination is_a: CCO:P0001807 ! regulation of histone ubiquitination [Term] id: CCO:P0001809 name: positive regulation of histone ubiquitination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin moiety to a histone protein." [GOC:mah] xref: GO:0033184 is_a: CCO:P0001369 ! positive regulation of histone modification is_a: CCO:P0001432 ! positive regulation of protein ubiquitination is_a: CCO:P0001807 ! regulation of histone ubiquitination [Term] id: CCO:P0001810 name: tumor necrosis factor-mediated signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor." [GOC:mah] synonym: "adipocytokine signaling pathway" RELATED [] synonym: "TNF-alpha-mediated signaling pathway" EXACT [] synonym: "tumor necrosis factor alpha-mediated signaling pathway" EXACT [] xref: GO:0033209 is_a: CCO:P0001144 ! cytokine and chemokine mediated signaling pathway relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0018189 ! PYDC1_HUMAN relationship: has_participant CCO:B0057268 ! COMD7_HUMAN relationship: has_participant CCO:B0058488 ! TXD17_HUMAN relationship: has_participant CCO:B0058693 ! LITFL_HUMAN [Term] id: CCO:P0001811 name: leptin-mediated signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of leptin binding to a cell surface receptor." [GOC:mah] synonym: "adipocytokine signaling pathway" RELATED [] xref: GO:0033210 is_a: CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:P0001812 name: adiponectin-mediated signaling pathway namespace: biological_process def: "A series of molecular signals generated as a consequence of adiponectin binding to a cell surface receptor." [GOC:mah] synonym: "adipocytokine signaling pathway" RELATED [] xref: GO:0033211 is_a: CCO:P0001144 ! cytokine and chemokine mediated signaling pathway [Term] id: CCO:P0001813 name: regulation of transcription from RNA polymerase II promoter in response to iron ion starvation namespace: biological_process def: "Modulation of the frequency, rate or extent of transcription from an from RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of iron ions." [GOC:mah] synonym: "regulation of transcription from RNA polymerase II promoter in response to iron deficiency" EXACT [] xref: GO:0033217 is_a: CCO:P0002249 ! regulation of transcription from RNA polymerase II promoter in response to stress [Term] id: CCO:P0001814 name: regulation of protein sumoylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the addition of SUMO moieties to a protein." [GOC:mah] synonym: "regulation of sumoylation" EXACT [] xref: GO:0033233 is_a: CCO:P0001433 ! regulation of protein modification process [Term] id: CCO:P0001815 name: negative regulation of protein sumoylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the addition of SUMO moieties to a protein." [GOC:mah] synonym: "negative regulation of sumoylation" EXACT [] xref: GO:0033234 is_a: CCO:P0001434 ! negative regulation of protein modification process is_a: CCO:P0001814 ! regulation of protein sumoylation [Term] id: CCO:P0001816 name: positive regulation of protein sumoylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the addition of SUMO moieties to a protein." [GOC:mah] synonym: "positive regulation of sumoylation" EXACT [] xref: GO:0033235 is_a: CCO:P0001435 ! positive regulation of protein modification process is_a: CCO:P0001814 ! regulation of protein sumoylation [Term] id: CCO:P0001817 name: regulation of amine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] subset: gosubset_prok synonym: "regulation of amine metabolism" EXACT [] xref: GO:0033238 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001818 name: negative regulation of amine metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "negative regulation of amine metabolism" EXACT [] xref: GO:0033239 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001817 ! regulation of amine metabolic process [Term] id: CCO:P0001819 name: positive regulation of amine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "positive regulation of amine metabolism" EXACT [] xref: GO:0033240 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001817 ! regulation of amine metabolic process [Term] id: CCO:P0001820 name: regulation of amine catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "regulation of amine breakdown" EXACT [] synonym: "regulation of amine catabolism" EXACT [] synonym: "regulation of amine degradation" EXACT [] xref: GO:0033241 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0001817 ! regulation of amine metabolic process [Term] id: CCO:P0001821 name: negative regulation of amine catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "negative regulation of amine breakdown" EXACT [] synonym: "negative regulation of amine catabolism" EXACT [] synonym: "negative regulation of amine degradation" EXACT [] xref: GO:0033242 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0001818 ! negative regulation of amine metabolic process is_a: CCO:P0001820 ! regulation of amine catabolic process [Term] id: CCO:P0001822 name: positive regulation of amine catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "positive regulation of amine breakdown" EXACT [] synonym: "positive regulation of amine catabolism" EXACT [] synonym: "positive regulation of amine degradation" EXACT [] xref: GO:0033243 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0001819 ! positive regulation of amine metabolic process is_a: CCO:P0001820 ! regulation of amine catabolic process [Term] id: CCO:P0001823 name: regulation of penicillin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] synonym: "regulation of penicillin metabolism" EXACT [] xref: GO:0033244 is_a: CCO:P0001817 ! regulation of amine metabolic process [Term] id: CCO:P0001824 name: negative regulation of penicillin metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] synonym: "negative regulation of penicillin metabolism" EXACT [] xref: GO:0033245 is_a: CCO:P0001818 ! negative regulation of amine metabolic process is_a: CCO:P0001823 ! regulation of penicillin metabolic process [Term] id: CCO:P0001825 name: positive regulation of penicillin metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] synonym: "positive regulation of penicillin metabolism" EXACT [] xref: GO:0033246 is_a: CCO:P0001819 ! positive regulation of amine metabolic process is_a: CCO:P0001823 ! regulation of penicillin metabolic process [Term] id: CCO:P0001826 name: regulation of penicillin catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] synonym: "regulation of penicillin breakdown" EXACT [] synonym: "regulation of penicillin catabolism" EXACT [] synonym: "regulation of penicillin degradation" EXACT [] xref: GO:0033247 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0001823 ! regulation of penicillin metabolic process [Term] id: CCO:P0001827 name: negative regulation of penicillin catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] synonym: "negative regulation of penicillin breakdown" EXACT [] synonym: "negative regulation of penicillin catabolism" EXACT [] synonym: "negative regulation of penicillin degradation" EXACT [] xref: GO:0033248 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0001824 ! negative regulation of penicillin metabolic process is_a: CCO:P0001826 ! regulation of penicillin catabolic process [Term] id: CCO:P0001828 name: positive regulation of penicillin catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system." [GOC:mah] synonym: "positive regulation of penicillin breakdown" EXACT [] synonym: "positive regulation of penicillin catabolism" EXACT [] synonym: "positive regulation of penicillin degradation" EXACT [] xref: GO:0033249 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0001825 ! positive regulation of penicillin metabolic process is_a: CCO:P0001826 ! regulation of penicillin catabolic process [Term] id: CCO:P0001829 name: plastid DNA replication namespace: biological_process def: "The process whereby new strands of DNA are synthesized in a plastid." [GOC:mah] synonym: "plastid DNA synthesis" RELATED [] synonym: "replication of plastid DNA" EXACT [] xref: GO:0033259 is_a: CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0001830 name: cell proliferation in midbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." [GOC:df] comment: This term was added by GO_REF:0000021. synonym: "cell proliferation in mesencephalon" EXACT [] synonym: "mesencepahalic cell proliferation" RELATED [] xref: GO:0033278 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001831 name: cotranscriptional gene silencing by small RNA namespace: biological_process def: "A process by which the targeting of nascent transcripts by the RITS complex mediates chromatin modifications and promotes the degradation of nascent transcripts synthesized in heterochromatic regions." [GOC:mah, PMID:17512405] synonym: "small RNA-mediated cotranscriptional gene silencing" EXACT [GOC:dph, GOC:tb] xref: GO:0033562 is_a: CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:P0001832 name: DNA replication, Okazaki fragment processing namespace: biological_process def: "The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand." [GOC:mah, ISBN:0716720094] xref: GO:0033567 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000637 ! lagging strand elongation [Term] id: CCO:P0001833 name: mammary gland epithelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk." [GOC:dph, GOC:mah] xref: GO:0033598 is_a: CCO:P0002917 ! epithelial cell proliferation [Term] id: CCO:P0001834 name: regulation of mammary gland epithelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation." [GOC:mah] xref: GO:0033599 is_a: CCO:P0002922 ! regulation of epithelial cell proliferation relationship: has_participant CCO:B0054910 ! GPX1_HUMAN relationship: regulates CCO:P0001833 ! mammary gland epithelial cell proliferation [Term] id: CCO:P0001835 name: negative regulation of mammary gland epithelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation." [GOC:mah] synonym: "down regulation of mammary gland epithelial cell proliferation" EXACT [] synonym: "down-regulation of mammary gland epithelial cell proliferation" EXACT [] synonym: "downregulation of mammary gland epithelial cell proliferation" EXACT [] synonym: "inhibition of mammary gland epithelial cell proliferation" NARROW [] xref: GO:0033600 is_a: CCO:P0001834 ! regulation of mammary gland epithelial cell proliferation is_a: CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: negatively_regulates CCO:P0001833 ! mammary gland epithelial cell proliferation [Term] id: CCO:P0001836 name: positive regulation of mammary gland epithelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation." [GOC:mah] synonym: "activation of mammary gland epithelial cell proliferation" NARROW [] synonym: "stimulation of mammary gland epithelial cell proliferation" NARROW [] synonym: "up regulation of mammary gland epithelial cell proliferation" EXACT [] synonym: "up-regulation of mammary gland epithelial cell proliferation" EXACT [] synonym: "upregulation of mammary gland epithelial cell proliferation" EXACT [] xref: GO:0033601 is_a: CCO:P0001834 ! regulation of mammary gland epithelial cell proliferation is_a: CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: positively_regulates CCO:P0001833 ! mammary gland epithelial cell proliferation [Term] id: CCO:P0001837 name: negative regulation of dopamine secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of dopamine." [GOC:sl] synonym: "down regulation of dopamine secretion" EXACT [] synonym: "down-regulation of dopamine secretion" EXACT [] synonym: "downregulation of dopamine secretion" EXACT [] synonym: "inhibition of dopamine secretion" NARROW [] xref: GO:0033602 is_a: CCO:P0001078 ! regulation of dopamine secretion is_a: CCO:P0001839 ! negative regulation of catecholamine secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0001838 name: positive regulation of dopamine secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine." [GOC:sl] synonym: "activation of dopamine secretion" NARROW [] synonym: "stimulation of dopamine secretion" NARROW [] synonym: "up regulation of dopamine secretion" EXACT [] synonym: "up-regulation of dopamine secretion" EXACT [] synonym: "upregulation of dopamine secretion" EXACT [] xref: GO:0033603 is_a: CCO:P0001078 ! regulation of dopamine secretion is_a: CCO:P0001840 ! positive regulation of catecholamine secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN [Term] id: CCO:P0001839 name: negative regulation of catecholamine secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "down regulation of catecholamine secretion" EXACT [] synonym: "down-regulation of catecholamine secretion" EXACT [] synonym: "downregulation of catecholamine secretion" EXACT [] synonym: "inhibition of catecholamine secretion" NARROW [] xref: GO:0033604 is_a: CCO:P0002750 ! negative regulation of neurotransmitter secretion is_a: CCO:P0002909 ! regulation of catecholamine secretion [Term] id: CCO:P0001840 name: positive regulation of catecholamine secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "activation of catecholamine secretion" NARROW [] synonym: "stimulation of catecholamine secretion" NARROW [] synonym: "up regulation of catecholamine secretion" EXACT [] synonym: "up-regulation of catecholamine secretion" EXACT [] synonym: "upregulation of catecholamine secretion" EXACT [] xref: GO:0033605 is_a: CCO:P0000510 ! positive regulation of neurotransmitter secretion is_a: CCO:P0002909 ! regulation of catecholamine secretion relationship: has_participant CCO:B0055180 ! ARBK1_HUMAN [Term] id: CCO:P0001841 name: regulation of integrin activation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of integrin activation." [GOC:add] synonym: "regulation of integrin complex activation" EXACT [] xref: GO:0033623 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process [Term] id: CCO:P0001842 name: negative regulation of integrin activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of integrin activation." [GOC:add] synonym: "negative regulation of integrin complex activation" EXACT [] xref: GO:0033624 is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process is_a: CCO:P0001841 ! regulation of integrin activation [Term] id: CCO:P0001843 name: positive regulation of integrin activation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of integrin activation." [GOC:add] synonym: "positive regulation of integrin complex activation" EXACT [] xref: GO:0033625 is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process is_a: CCO:P0001841 ! regulation of integrin activation [Term] id: CCO:P0001844 name: cell surface receptor linked signal transduction leading to integrin activation namespace: biological_process def: "Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands." [GOC:add, PMID:12213832, PMID:14754902] synonym: "cell surface receptor linked signal transduction leading to integrin complex activation" EXACT [] xref: GO:0033626 is_a: CCO:P0000709 ! cell surface receptor linked signal transduction [Term] id: CCO:P0001845 name: regulation of cell adhesion mediated by integrin namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin." [GOC:add] synonym: "regulation of cell adhesion mediated by integrin complex" EXACT [] xref: GO:0033628 is_a: CCO:P0001245 ! regulation of cell adhesion [Term] id: CCO:P0001846 name: negative regulation of cell adhesion mediated by integrin namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of cell adhesion mediated by integrin." [GOC:add] synonym: "negative regulation of cell adhesion mediated by integrin complex" EXACT [] xref: GO:0033629 is_a: CCO:P0000707 ! negative regulation of cell adhesion is_a: CCO:P0001845 ! regulation of cell adhesion mediated by integrin [Term] id: CCO:P0001847 name: positive regulation of cell adhesion mediated by integrin namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin." [GOC:add] synonym: "positive regulation of cell adhesion mediated by integrin complex" EXACT [] xref: GO:0033630 is_a: CCO:P0001845 ! regulation of cell adhesion mediated by integrin is_a: CCO:P0002553 ! positive regulation of cell adhesion [Term] id: CCO:P0001848 name: regulation of cell-cell adhesion mediated by integrin namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin." [GOC:add] synonym: "regulation of cell-cell adhesion mediated by integrin complex" EXACT [] xref: GO:0033632 is_a: CCO:P0001237 ! regulation of cell-cell adhesion is_a: CCO:P0001845 ! regulation of cell adhesion mediated by integrin relationship: has_participant CCO:B0038734 ! DPP4_HUMAN relationship: has_participant CCO:B0054829 ! ADA_HUMAN [Term] id: CCO:P0001849 name: negative regulation of cell-cell adhesion mediated by integrin namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin." [GOC:add] synonym: "negative regulation of cell-cell adhesion mediated by integrin complex" EXACT [] xref: GO:0033633 is_a: CCO:P0001238 ! negative regulation of cell-cell adhesion is_a: CCO:P0001846 ! negative regulation of cell adhesion mediated by integrin is_a: CCO:P0001848 ! regulation of cell-cell adhesion mediated by integrin [Term] id: CCO:P0001850 name: positive regulation of cell-cell adhesion mediated by integrin namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin." [GOC:add] synonym: "positive regulation of cell-cell adhesion mediated by integrin complex" EXACT [] xref: GO:0033634 is_a: CCO:P0001239 ! positive regulation of cell-cell adhesion is_a: CCO:P0001847 ! positive regulation of cell adhesion mediated by integrin is_a: CCO:P0001848 ! regulation of cell-cell adhesion mediated by integrin [Term] id: CCO:P0001851 name: negative regulation by symbiont of host apoptosis namespace: biological_process def: "Any process by which an organism stops, prevents or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] comment: Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of apoptosis ; GO:0043066'. synonym: "down regulation by organism of host apoptotic programmed cell death" EXACT [] synonym: "down-regulation by organism of host apoptotic programmed cell death" EXACT [] synonym: "downregulation by organism of host apoptotic programmed cell death" EXACT [] synonym: "inhibition by organism of host apoptotic programmed cell death" NARROW [] xref: GO:0033668 is_a: CCO:P0002148 ! negative regulation of apoptosis is_a: CCO:P0003184 ! negative regulation by symbiont of host programmed cell death is_a: CCO:P0003189 ! modulation by symbiont of host apoptosis [Term] id: CCO:P0001852 name: regulation of luteinizing hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone." [GOC:mah] xref: GO:0033684 is_a: CCO:P0001578 ! regulation of gonadotropin secretion [Term] id: CCO:P0001853 name: negative regulation of luteinizing hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of luteinizing hormone." [GOC:mah] synonym: "down regulation of luteinizing hormone secretion" EXACT [] synonym: "down-regulation of luteinizing hormone secretion" EXACT [] synonym: "downregulation of luteinizing hormone secretion" EXACT [] synonym: "inhibition of luteinizing hormone secretion" NARROW [] xref: GO:0033685 is_a: CCO:P0001579 ! negative regulation of gonadotropin secretion is_a: CCO:P0001852 ! regulation of luteinizing hormone secretion [Term] id: CCO:P0001854 name: positive regulation of luteinizing hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone." [GOC:mah] synonym: "activation of luteinizing hormone secretion" NARROW [] synonym: "stimulation of luteinizing hormone secretion" NARROW [] synonym: "up regulation of luteinizing hormone secretion" EXACT [] synonym: "up-regulation of luteinizing hormone secretion" EXACT [] synonym: "upregulation of luteinizing hormone secretion" EXACT [] xref: GO:0033686 is_a: CCO:P0001580 ! positive regulation of gonadotropin secretion is_a: CCO:P0001852 ! regulation of luteinizing hormone secretion [Term] id: CCO:P0001855 name: osteoblast proliferation namespace: biological_process def: "The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone." [GOC:mah] xref: GO:0033687 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0001856 name: regulation of osteoblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of osteoblast proliferation." [GOC:mah] xref: GO:0033688 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0001855 ! osteoblast proliferation [Term] id: CCO:P0001857 name: negative regulation of osteoblast proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation." [GOC:mah] synonym: "down regulation of osteoblast proliferation" EXACT [] synonym: "down-regulation of osteoblast proliferation" EXACT [] synonym: "downregulation of osteoblast proliferation" EXACT [] synonym: "inhibition of osteoblast proliferation" NARROW [] xref: GO:0033689 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0001856 ! regulation of osteoblast proliferation relationship: negatively_regulates CCO:P0001855 ! osteoblast proliferation [Term] id: CCO:P0001858 name: positive regulation of osteoblast proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of osteoblast proliferation." [GOC:mah] synonym: "activation of osteoblast proliferation" NARROW [] synonym: "stimulation of osteoblast proliferation" NARROW [] synonym: "up regulation of osteoblast proliferation" EXACT [] synonym: "up-regulation of osteoblast proliferation" EXACT [] synonym: "upregulation of osteoblast proliferation" EXACT [] xref: GO:0033690 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0001856 ! regulation of osteoblast proliferation relationship: positively_regulates CCO:P0001855 ! osteoblast proliferation [Term] id: CCO:P0001859 name: negative regulation of extent of heterochromatin formation namespace: biological_process def: "Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin." [GOC:mah] synonym: "maintenance of heterochromatin boundaries" RELATED [] synonym: "negative regulation of heterochromatin spreading" RELATED [] xref: GO:0033696 is_a: CCO:P0001443 ! negative regulation of heterochromatin formation is_a: CCO:P0001445 ! regulation of extent of heterochromatin formation [Term] id: CCO:P0001860 name: positive regulation of extent of heterochromatin formation namespace: biological_process def: "Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin." [GOC:mah] synonym: "positive regulation of heterochromatin spreading" RELATED [] xref: GO:0033697 is_a: CCO:P0001444 ! positive regulation of heterochromatin formation is_a: CCO:P0001445 ! regulation of extent of heterochromatin formation [Term] id: CCO:P0001861 name: negative regulation of plant-type hypersensitive response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the hypersensitive response in a plant." [GOC:pamgo_curators] synonym: "down regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] synonym: "down-regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] synonym: "downregulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] synonym: "inhibition of plant-type hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "negative regulation of HR" EXACT [GOC:pamgo_curators] synonym: "negative regulation of HR-PCD" EXACT [GOC:pamgo_curators] synonym: "negative regulation of plant hypersensitive response" EXACT [GOC:pamgo_curators] xref: GO:0034051 is_a: CCO:P0000926 ! regulation of plant-type hypersensitive response is_a: CCO:P0002151 ! negative regulation of programmed cell death [Term] id: CCO:P0001862 name: positive regulation of plant-type hypersensitive response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant." [GOC:pamgo_curators] synonym: "activation of plant-type hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "positive regulation of HR" EXACT [GOC:pamgo_curators] synonym: "positive regulation of HR-PCD" RELATED [GOC:pamgo_curators] synonym: "positive regulation of plant hypersensitive response" EXACT [GOC:pamgo_curators] synonym: "stimulation of plant-type hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "up regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] synonym: "up-regulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] synonym: "upregulation of plant-type hypersensitive response" EXACT [GOC:pamgo_curators] xref: GO:0034052 is_a: CCO:P0000926 ! regulation of plant-type hypersensitive response is_a: CCO:P0002150 ! positive regulation of programmed cell death [Term] id: CCO:P0001863 name: modulation by symbiont of host defense-related programmed cell death namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'plant-type hypersensitive response ; GO:0009626'. synonym: "modulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators] synonym: "modulation by symbiont of host HR" NARROW [GOC:pamgo_curators] synonym: "modulation by symbiont of host hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "modulation by symbiont of plant HR" NARROW [GOC:pamgo_curators] synonym: "modulation by symbiont of plant hypersensitive response" NARROW [GOC:pamgo_curators] xref: GO:0034053 is_a: CCO:P0003183 ! modulation by symbiont of host programmed cell death [Term] id: CCO:P0001864 name: negative regulation by symbiont of host defense-related programmed cell death namespace: biological_process def: "Any process by which an organism stops, prevents or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators] comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of plant-type hypersensitive response ; GO:0034051'. synonym: "down regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] synonym: "down-regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] synonym: "downregulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] synonym: "inhibition by symbiont of host defense-related PCD" NARROW [GOC:pamgo_curators] synonym: "inhibition by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] synonym: "inhibition of host defense-related PCD" NARROW [GOC:pamgo_curators] synonym: "inhibition of HR" NARROW [GOC:pamgo_curators] synonym: "inhibition of hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "negative regulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators] synonym: "negative regulation by symbiont of plant HR" NARROW [GOC:pamgo_curators] synonym: "negative regulation by symbiont of plant hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "suppression by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] synonym: "suppression of HR" NARROW [GOC:pamgo_curators] xref: GO:0034054 is_a: CCO:P0001863 ! modulation by symbiont of host defense-related programmed cell death is_a: CCO:P0003184 ! negative regulation by symbiont of host programmed cell death [Term] id: CCO:P0001865 name: positive regulation by symbiont of host defense-related programmed cell death namespace: biological_process comment: Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'positive regulation of plant-type hypersensitive response ; GO:0034052'. synonym: "activation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] synonym: "activation of HR" NARROW [GOC:pamgo_curators] synonym: "activation of hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "enhancement by symbiont of host defense-related PCDprogrammed cell death" NARROW [GOC:pamgo_curators] synonym: "positive regulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators] synonym: "positive regulation by symbiont of plant HR" NARROW [GOC:pamgo_curators] synonym: "positive regulation by symbiont of plant hypersensitive response" NARROW [GOC:pamgo_curators] synonym: "stimulation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators] synonym: "up regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] synonym: "up-regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] synonym: "upregulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators] xref: GO:0034055 is_a: CCO:P0001863 ! modulation by symbiont of host defense-related programmed cell death is_a: CCO:P0003185 ! positive regulation by symbiont of host programmed cell death [Term] id: CCO:P0001866 name: regulation of homotypic cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion." [GOC:add] xref: GO:0034110 is_a: CCO:P0001237 ! regulation of cell-cell adhesion [Term] id: CCO:P0001867 name: negative regulation of homotypic cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of homotypic cell-cell adhesion." [GOC:add] xref: GO:0034111 is_a: CCO:P0001238 ! negative regulation of cell-cell adhesion is_a: CCO:P0001866 ! regulation of homotypic cell-cell adhesion [Term] id: CCO:P0001868 name: positive regulation of homotypic cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion." [GOC:add] xref: GO:0034112 is_a: CCO:P0001239 ! positive regulation of cell-cell adhesion is_a: CCO:P0001866 ! regulation of homotypic cell-cell adhesion [Term] id: CCO:P0001869 name: regulation of heterotypic cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion." [GOC:add] xref: GO:0034114 is_a: CCO:P0001237 ! regulation of cell-cell adhesion [Term] id: CCO:P0001870 name: negative regulation of heterotypic cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion." [GOC:add] xref: GO:0034115 is_a: CCO:P0001238 ! negative regulation of cell-cell adhesion is_a: CCO:P0001869 ! regulation of heterotypic cell-cell adhesion [Term] id: CCO:P0001871 name: positive regulation of heterotypic cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion." [GOC:add] xref: GO:0034116 is_a: CCO:P0001239 ! positive regulation of cell-cell adhesion is_a: CCO:P0001869 ! regulation of heterotypic cell-cell adhesion [Term] id: CCO:P0001872 name: regulation of erythrocyte aggregation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of erythrocyte aggregation." [GOC:add] xref: GO:0034118 is_a: CCO:P0001866 ! regulation of homotypic cell-cell adhesion [Term] id: CCO:P0001873 name: negative regulation of erythrocyte aggregation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of erythrocyte aggregation." [GOC:add] xref: GO:0034119 is_a: CCO:P0001867 ! negative regulation of homotypic cell-cell adhesion is_a: CCO:P0001872 ! regulation of erythrocyte aggregation [Term] id: CCO:P0001874 name: positive regulation of erythrocyte aggregation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation." [GOC:add] xref: GO:0034120 is_a: CCO:P0001868 ! positive regulation of homotypic cell-cell adhesion is_a: CCO:P0001872 ! regulation of erythrocyte aggregation [Term] id: CCO:P0001875 name: regulation of toll-like receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR signaling pathway" EXACT [] synonym: "regulation of toll-like receptor signalling pathway" EXACT [] xref: GO:0034121 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001876 name: negative regulation of toll-like receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor signalling pathway" EXACT [] xref: GO:0034122 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: negatively_regulates CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001877 name: positive regulation of toll-like receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor signalling pathway" EXACT [] xref: GO:0034123 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: positively_regulates CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001878 name: regulation of MyD88-dependent toll-like receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation ofMyD88-dependent TLR signaling pathway" EXACT [] synonym: "regulation ofMyD88-dependent toll-like receptor signalling pathway" EXACT [] xref: GO:0034124 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0000571 ! MyD88-dependent toll-like receptor signaling pathway [Term] id: CCO:P0001879 name: negative regulation of MyD88-dependent toll-like receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of MyD88-dependent TLR signaling pathway" EXACT [] synonym: "negative regulation of MyD88-dependent toll-like receptor signalling pathway" EXACT [] xref: GO:0034125 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001878 ! regulation of MyD88-dependent toll-like receptor signaling pathway relationship: negatively_regulates CCO:P0000571 ! MyD88-dependent toll-like receptor signaling pathway [Term] id: CCO:P0001880 name: positive regulation of MyD88-dependent toll-like receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of MyD88-dependent TLR signaling pathway" EXACT [] synonym: "positive regulation of MyD88-dependent toll-like receptor signalling pathway" EXACT [] xref: GO:0034126 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001878 ! regulation of MyD88-dependent toll-like receptor signaling pathway relationship: positively_regulates CCO:P0000571 ! MyD88-dependent toll-like receptor signaling pathway [Term] id: CCO:P0001881 name: regulation of MyD88-independent toll-like receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation ofMyD88-independent TLR signaling pathway" EXACT [] synonym: "regulation ofMyD88-independent toll-like receptor signalling pathway" EXACT [] xref: GO:0034127 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0000572 ! MyD88-independent toll-like receptor signaling pathway [Term] id: CCO:P0001882 name: negative regulation of MyD88-independent toll-like receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of MyD88-independent TLR signaling pathway" EXACT [] synonym: "negative regulation of MyD88-independent toll-like receptor signalling pathway" EXACT [] xref: GO:0034128 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001881 ! regulation of MyD88-independent toll-like receptor signaling pathway relationship: negatively_regulates CCO:P0000572 ! MyD88-independent toll-like receptor signaling pathway [Term] id: CCO:P0001883 name: positive regulation of MyD88-independent toll-like receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of MyD88-independent TLR signaling pathway" EXACT [] synonym: "positive regulation of MyD88-independent toll-like receptor" EXACT [] xref: GO:0034129 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001881 ! regulation of MyD88-independent toll-like receptor signaling pathway relationship: positively_regulates CCO:P0000572 ! MyD88-independent toll-like receptor signaling pathway [Term] id: CCO:P0001884 name: toll-like receptor 1 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 1." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR1 signaling pathway" EXACT [] synonym: "toll-like receptor 1 signalling pathway" EXACT [] xref: GO:0034130 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001885 name: regulation of toll-like receptor 1 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR1 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 1 signalling pathway" EXACT [] xref: GO:0034131 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001884 ! toll-like receptor 1 signaling pathway [Term] id: CCO:P0001886 name: negative regulation of toll-like receptor 1 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR1 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 1 signalling pathway" EXACT [] xref: GO:0034132 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001885 ! regulation of toll-like receptor 1 signaling pathway relationship: negatively_regulates CCO:P0001884 ! toll-like receptor 1 signaling pathway [Term] id: CCO:P0001887 name: positive regulation of toll-like receptor 1 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR1 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 1 signalling pathway" EXACT [] xref: GO:0034133 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001885 ! regulation of toll-like receptor 1 signaling pathway relationship: positively_regulates CCO:P0001884 ! toll-like receptor 1 signaling pathway [Term] id: CCO:P0001888 name: toll-like receptor 2 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 2." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR2 signaling pathway" EXACT [] synonym: "toll-like receptor 2 signalling pathway" EXACT [] xref: GO:0034134 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001889 name: regulation of toll-like receptor 2 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR2 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 2 signalling pathway" EXACT [] xref: GO:0034135 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001888 ! toll-like receptor 2 signaling pathway [Term] id: CCO:P0001890 name: negative regulation of toll-like receptor 2 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR2 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 2 signalling pathway" EXACT [] xref: GO:0034136 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001889 ! regulation of toll-like receptor 2 signaling pathway relationship: negatively_regulates CCO:P0001888 ! toll-like receptor 2 signaling pathway [Term] id: CCO:P0001891 name: positive regulation of toll-like receptor 2 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR2 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 2 signalling pathway" EXACT [] xref: GO:0034137 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001889 ! regulation of toll-like receptor 2 signaling pathway relationship: positively_regulates CCO:P0001888 ! toll-like receptor 2 signaling pathway [Term] id: CCO:P0001892 name: toll-like receptor 3 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 3." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR3 signaling pathway" EXACT [] synonym: "toll-like receptor 3 signalling pathway" EXACT [] xref: GO:0034138 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001893 name: regulation of toll-like receptor 3 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR3 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 3 signalling pathway" EXACT [] xref: GO:0034139 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001892 ! toll-like receptor 3 signaling pathway [Term] id: CCO:P0001894 name: negative regulation of toll-like receptor 3 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR3 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 3 signalling pathway" EXACT [] xref: GO:0034140 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001893 ! regulation of toll-like receptor 3 signaling pathway relationship: negatively_regulates CCO:P0001892 ! toll-like receptor 3 signaling pathway [Term] id: CCO:P0001895 name: positive regulation of toll-like receptor 3 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR3 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 3 signalling pathway" EXACT [] xref: GO:0034141 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001893 ! regulation of toll-like receptor 3 signaling pathway relationship: positively_regulates CCO:P0001892 ! toll-like receptor 3 signaling pathway [Term] id: CCO:P0001896 name: toll-like receptor 4 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 4." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR4 signaling pathway" EXACT [] synonym: "toll-like receptor 4 signalling pathway" EXACT [] xref: GO:0034142 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001897 name: regulation of toll-like receptor 4 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR4 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 4 signalling pathway" EXACT [] xref: GO:0034143 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001896 ! toll-like receptor 4 signaling pathway [Term] id: CCO:P0001898 name: negative regulation of toll-like receptor 4 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR4 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 4 signalling pathway" EXACT [] xref: GO:0034144 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001897 ! regulation of toll-like receptor 4 signaling pathway relationship: negatively_regulates CCO:P0001896 ! toll-like receptor 4 signaling pathway [Term] id: CCO:P0001899 name: positive regulation of toll-like receptor 4 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR4 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 4 signalling pathway" EXACT [] xref: GO:0034145 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001897 ! regulation of toll-like receptor 4 signaling pathway relationship: positively_regulates CCO:P0001896 ! toll-like receptor 4 signaling pathway [Term] id: CCO:P0001900 name: toll-like receptor 5 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 5." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR5 signaling pathway" EXACT [] synonym: "toll-like receptor 5 signalling pathway" EXACT [] xref: GO:0034146 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001901 name: regulation of toll-like receptor 5 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR5 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 5 signalling pathway" EXACT [] xref: GO:0034147 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001900 ! toll-like receptor 5 signaling pathway [Term] id: CCO:P0001902 name: negative regulation of toll-like receptor 5 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR5 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 5 signalling pathway" EXACT [] xref: GO:0034148 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001901 ! regulation of toll-like receptor 5 signaling pathway relationship: negatively_regulates CCO:P0001900 ! toll-like receptor 5 signaling pathway [Term] id: CCO:P0001903 name: positive regulation of toll-like receptor 5 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR5 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 5 signalling pathway" EXACT [] xref: GO:0034149 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001901 ! regulation of toll-like receptor 5 signaling pathway relationship: positively_regulates CCO:P0001900 ! toll-like receptor 5 signaling pathway [Term] id: CCO:P0001904 name: toll-like receptor 6 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 6." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR6 signaling pathway" EXACT [] synonym: "toll-like receptor 6 signalling pathway" EXACT [] xref: GO:0034150 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001905 name: regulation of toll-like receptor 6 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR6 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 6 signalling pathway" EXACT [] xref: GO:0034151 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001904 ! toll-like receptor 6 signaling pathway [Term] id: CCO:P0001906 name: negative regulation of toll-like receptor 6 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR6 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 6 signalling pathway" EXACT [] xref: GO:0034152 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001905 ! regulation of toll-like receptor 6 signaling pathway relationship: negatively_regulates CCO:P0001904 ! toll-like receptor 6 signaling pathway [Term] id: CCO:P0001907 name: positive regulation of toll-like receptor 6 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR6 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 6 signalling pathway" EXACT [] xref: GO:0034153 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001905 ! regulation of toll-like receptor 6 signaling pathway relationship: positively_regulates CCO:P0001904 ! toll-like receptor 6 signaling pathway [Term] id: CCO:P0001908 name: toll-like receptor 7 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 7." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR7 signaling pathway" EXACT [] synonym: "toll-like receptor 7 signalling pathway" EXACT [] xref: GO:0034154 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001909 name: regulation of toll-like receptor 7 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR7 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 7 signalling pathway" EXACT [] xref: GO:0034155 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001908 ! toll-like receptor 7 signaling pathway [Term] id: CCO:P0001910 name: negative regulation of toll-like receptor 7 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR7 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 7 signalling pathway" EXACT [] xref: GO:0034156 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001909 ! regulation of toll-like receptor 7 signaling pathway relationship: negatively_regulates CCO:P0001908 ! toll-like receptor 7 signaling pathway [Term] id: CCO:P0001911 name: positive regulation of toll-like receptor 7 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR7 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 7 signalling pathway" EXACT [] xref: GO:0034157 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001909 ! regulation of toll-like receptor 7 signaling pathway relationship: positively_regulates CCO:P0001908 ! toll-like receptor 7 signaling pathway [Term] id: CCO:P0001912 name: toll-like receptor 8 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 8." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR8 signaling pathway" EXACT [] synonym: "toll-like receptor 8 signalling pathway" EXACT [] xref: GO:0034158 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001913 name: regulation of toll-like receptor 8 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR8 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 8 signalling pathway" EXACT [] xref: GO:0034159 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001912 ! toll-like receptor 8 signaling pathway [Term] id: CCO:P0001914 name: negative regulation of toll-like receptor 8 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR8 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 8 signalling pathway" EXACT [] xref: GO:0034160 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001913 ! regulation of toll-like receptor 8 signaling pathway relationship: negatively_regulates CCO:P0001912 ! toll-like receptor 8 signaling pathway [Term] id: CCO:P0001915 name: positive regulation of toll-like receptor 8 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR8 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 8 signalling pathway" EXACT [] xref: GO:0034161 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001913 ! regulation of toll-like receptor 8 signaling pathway relationship: positively_regulates CCO:P0001912 ! toll-like receptor 8 signaling pathway [Term] id: CCO:P0001916 name: toll-like receptor 9 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 9." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR9 signaling pathway" EXACT [] synonym: "toll-like receptor 9 signalling pathway" EXACT [] xref: GO:0034162 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001917 name: regulation of toll-like receptor 9 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR9 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 9 signalling pathway" EXACT [] xref: GO:0034163 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001916 ! toll-like receptor 9 signaling pathway [Term] id: CCO:P0001918 name: negative regulation of toll-like receptor 9 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR9 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 9 signalling pathway" EXACT [] xref: GO:0034164 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001917 ! regulation of toll-like receptor 9 signaling pathway relationship: negatively_regulates CCO:P0001916 ! toll-like receptor 9 signaling pathway [Term] id: CCO:P0001919 name: positive regulation of toll-like receptor 9 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR9 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 9 signalling pathway" EXACT [] xref: GO:0034165 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001917 ! regulation of toll-like receptor 9 signaling pathway relationship: positively_regulates CCO:P0001916 ! toll-like receptor 9 signaling pathway [Term] id: CCO:P0001920 name: toll-like receptor 10 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 10." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR10 signaling pathway" EXACT [] synonym: "toll-like receptor 10 signalling pathway" EXACT [] xref: GO:0034166 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001921 name: regulation of toll-like receptor 10 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR10 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 10 signalling pathway" EXACT [] xref: GO:0034167 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001920 ! toll-like receptor 10 signaling pathway [Term] id: CCO:P0001922 name: negative regulation of toll-like receptor 10 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR10 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 10 signalling pathway" EXACT [] xref: GO:0034168 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001921 ! regulation of toll-like receptor 10 signaling pathway relationship: negatively_regulates CCO:P0001920 ! toll-like receptor 10 signaling pathway [Term] id: CCO:P0001923 name: positive regulation of toll-like receptor 10 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR10 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 10 signalling pathway" EXACT [] xref: GO:0034169 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001921 ! regulation of toll-like receptor 10 signaling pathway relationship: positively_regulates CCO:P0001920 ! toll-like receptor 10 signaling pathway [Term] id: CCO:P0001924 name: toll-like receptor 11 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 11." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR11 signaling pathway" EXACT [] synonym: "toll-like receptor 11 signalling pathway" EXACT [] xref: GO:0034170 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001925 name: regulation of toll-like receptor 11 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR11 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 11 signalling pathway" EXACT [] xref: GO:0034171 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001924 ! toll-like receptor 11 signaling pathway [Term] id: CCO:P0001926 name: negative regulation of toll-like receptor 11 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR11 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 11 signalling pathway" EXACT [] xref: GO:0034172 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001925 ! regulation of toll-like receptor 11 signaling pathway relationship: negatively_regulates CCO:P0001924 ! toll-like receptor 11 signaling pathway [Term] id: CCO:P0001927 name: positive regulation of toll-like receptor 11 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR11 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 11 signalling pathway" EXACT [] xref: GO:0034173 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001925 ! regulation of toll-like receptor 11 signaling pathway relationship: positively_regulates CCO:P0001924 ! toll-like receptor 11 signaling pathway [Term] id: CCO:P0001928 name: toll-like receptor 12 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 12." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR12 signaling pathway" EXACT [] synonym: "toll-like receptor 12 signalling pathway" EXACT [] xref: GO:0034174 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001929 name: regulation of toll-like receptor 12 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR12 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 12 signalling pathway" EXACT [] xref: GO:0034175 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001928 ! toll-like receptor 12 signaling pathway [Term] id: CCO:P0001930 name: negative regulation of toll-like receptor 12 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR12 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 12 signalling pathway" EXACT [] xref: GO:0034176 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001929 ! regulation of toll-like receptor 12 signaling pathway relationship: negatively_regulates CCO:P0001928 ! toll-like receptor 12 signaling pathway [Term] id: CCO:P0001931 name: positive regulation of toll-like receptor 12 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR12 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 12 signalling pathway" EXACT [] xref: GO:0034177 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001929 ! regulation of toll-like receptor 12 signaling pathway relationship: positively_regulates CCO:P0001928 ! toll-like receptor 12 signaling pathway [Term] id: CCO:P0001932 name: toll-like receptor 13 signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of binding to toll-like receptor 13." [GOC:add, PMID:16551253, PMID:17328678] synonym: "TLR13 signaling pathway" EXACT [] synonym: "toll-like receptor 13 signalling pathway" EXACT [] xref: GO:0034178 is_a: CCO:P0000535 ! toll-like receptor signaling pathway [Term] id: CCO:P0001933 name: regulation of toll-like receptor 13 signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "regulation of TLR13 signaling pathway" EXACT [] synonym: "regulation of toll-like receptor 13 signalling pathway" EXACT [] xref: GO:0034179 is_a: CCO:P0001875 ! regulation of toll-like receptor signaling pathway relationship: regulates CCO:P0001932 ! toll-like receptor 13 signaling pathway [Term] id: CCO:P0001934 name: negative regulation of toll-like receptor 13 signaling pathway namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "negative regulation of TLR13 signaling pathway" EXACT [] synonym: "negative regulation of toll-like receptor 13 signalling pathway" EXACT [] xref: GO:0034180 is_a: CCO:P0001876 ! negative regulation of toll-like receptor signaling pathway is_a: CCO:P0001933 ! regulation of toll-like receptor 13 signaling pathway relationship: negatively_regulates CCO:P0001932 ! toll-like receptor 13 signaling pathway [Term] id: CCO:P0001935 name: positive regulation of toll-like receptor 13 signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway." [GOC:add, PMID:16551253, PMID:17328678] synonym: "positive regulation of TLR13 signaling pathway" EXACT [] synonym: "positive regulation of toll-like receptor 13 signalling pathway" EXACT [] xref: GO:0034181 is_a: CCO:P0001877 ! positive regulation of toll-like receptor signaling pathway is_a: CCO:P0001933 ! regulation of toll-like receptor 13 signaling pathway relationship: positively_regulates CCO:P0001932 ! toll-like receptor 13 signaling pathway [Term] id: CCO:P0001936 name: ascospore wall chitin biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores." [GOC:mah] synonym: "ascospore wall chitin anabolism" EXACT [] synonym: "ascospore wall chitin biosynthesis" EXACT [] synonym: "ascospore wall chitin formation" EXACT [] synonym: "ascospore wall chitin synthesis" EXACT [] xref: GO:0034217 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001267 ! ascospore wall assembly [Term] id: CCO:P0001937 name: regulation of cell wall chitin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall." [GOC:mah] synonym: "regulation of cell wall chitin metabolism" EXACT [] xref: GO:0034222 is_a: CCO:P0001700 ! regulation of chitin metabolic process is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0001938 name: regulation of ascospore wall chitin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin." [GOC:mah] synonym: "regulation of ascospore wall chitin anabolism" EXACT [] synonym: "regulation of ascospore wall chitin biosynthesis" EXACT [] synonym: "regulation of ascospore wall chitin formation" EXACT [] synonym: "regulation of ascospore wall chitin synthesis" EXACT [] xref: GO:0034223 is_a: CCO:P0001702 ! regulation of cell wall chitin biosynthetic process relationship: regulates CCO:P0001936 ! ascospore wall chitin biosynthetic process [Term] id: CCO:P0001939 name: regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation namespace: biological_process def: "Modulation of the frequency, rate or extent of transcription from an from RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions." [GOC:mah] synonym: "regulation of transcription from RNA polymerase II promoter in response to zinc deficiency" EXACT [] synonym: "regulation of transcription from RNA polymerase II promoter in response to zinc ion limitation" EXACT [] xref: GO:0034225 is_a: CCO:P0002249 ! regulation of transcription from RNA polymerase II promoter in response to stress [Term] id: CCO:P0001940 name: regulation of cell wall chitin catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin." [GOC:mah] synonym: "regulation of cell wall chitin breakdown" EXACT [] synonym: "regulation of cell wall chitin catabolism" EXACT [] synonym: "regulation of cell wall chitin degradation" EXACT [] xref: GO:0034233 is_a: CCO:P0001937 ! regulation of cell wall chitin metabolic process is_a: CCO:P0002220 ! regulation of cellular carbohydrate catabolic process [Term] id: CCO:P0001941 name: regulation of ascospore wall chitin catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin." [GOC:mah] synonym: "regulation of ascospore wall chitin breakdown" EXACT [] synonym: "regulation of ascospore wall chitin catabolism" EXACT [] synonym: "regulation of ascospore wall chitin degradation" EXACT [] xref: GO:0034234 is_a: CCO:P0001940 ! regulation of cell wall chitin catabolic process [Term] id: CCO:P0001942 name: regulation of macrophage fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of macrophage fusion." [GOC:mah] xref: GO:0034239 is_a: CCO:P0003255 ! regulation of syncytium formation by plasma membrane fusion [Term] id: CCO:P0001943 name: negative regulation of macrophage fusion namespace: biological_process def: "Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion." [GOC:mah] xref: GO:0034240 is_a: CCO:P0001942 ! regulation of macrophage fusion is_a: CCO:P0001945 ! negative regulation of syncytium formation by plasma membrane fusion [Term] id: CCO:P0001944 name: positive regulation of macrophage fusion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of macrophage fusion." [GOC:mah] xref: GO:0034241 is_a: CCO:P0001942 ! regulation of macrophage fusion is_a: CCO:P0003256 ! positive regulation of syncytium formation by plasma membrane fusion [Term] id: CCO:P0001945 name: negative regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mah] xref: GO:0034242 is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis is_a: CCO:P0003255 ! regulation of syncytium formation by plasma membrane fusion [Term] id: CCO:P0001946 name: regulation of RNA elongation from RNA polymerase II promoter namespace: biological_process def: "Any process that modulates the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides, catalyzed by RNA polymerase II." [GOC:mah] synonym: "regulation of transcription elongation from RNA polymerase II promoter" BROAD [] xref: GO:0034243 is_a: CCO:P0001647 ! regulation of RNA elongation [Term] id: CCO:P0001947 name: negative regulation of RNA elongation from RNA polymerase II promoter namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of RNA elongation, the extension of an RNA molecule after transcription initiation by the addition of ribonucleotides, catalyzed by RNA polymerase II." [GOC:mah] synonym: "negative regulation of transcription elongation from RNA polymerase II promoter" BROAD [] xref: GO:0034244 is_a: CCO:P0001648 ! negative regulation of RNA elongation is_a: CCO:P0001946 ! regulation of RNA elongation from RNA polymerase II promoter [Term] id: CCO:P0001948 name: regulation of amide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "regulation of amide metabolism" EXACT [] xref: GO:0034248 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001949 name: negative regulation of amide metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "negative regulation of amide metabolism" EXACT [] xref: GO:0034249 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001948 ! regulation of amide metabolic process [Term] id: CCO:P0001950 name: positive regulation of amide metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "positive regulation of amide metabolism" EXACT [] xref: GO:0034250 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001948 ! regulation of amide metabolic process [Term] id: CCO:P0001951 name: regulation of amide catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "regulation of amide breakdown" EXACT [] synonym: "regulation of amide catabolism" EXACT [] synonym: "regulation of amide degradation" EXACT [] xref: GO:0034251 is_a: CCO:P0001948 ! regulation of amide metabolic process [Term] id: CCO:P0001952 name: negative regulation of amide catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "negative regulation of amide breakdown" EXACT [] synonym: "negative regulation of amide catabolism" EXACT [] synonym: "negative regulation of amide degradation" RELATED [] xref: GO:0034252 is_a: CCO:P0001949 ! negative regulation of amide metabolic process is_a: CCO:P0001951 ! regulation of amide catabolic process [Term] id: CCO:P0001953 name: positive regulation of amide catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "positive regulation of amide breakdown" EXACT [] synonym: "positive regulation of amide catabolism" EXACT [] synonym: "positive regulation of amide degradation" RELATED [] xref: GO:0034253 is_a: CCO:P0001950 ! positive regulation of amide metabolic process is_a: CCO:P0001951 ! regulation of amide catabolic process [Term] id: CCO:P0001954 name: regulation of urea catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea." [GOC:mah] synonym: "regulation of urea breakdown" EXACT [] synonym: "regulation of urea catabolism" EXACT [] synonym: "regulation of urea degradation" EXACT [] xref: GO:0034254 is_a: CCO:P0001951 ! regulation of amide catabolic process is_a: CCO:P0001955 ! regulation of urea metabolic process [Term] id: CCO:P0001955 name: regulation of urea metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea." [GOC:mah] synonym: "regulation of urea metabolism" EXACT [] xref: GO:0034255 is_a: CCO:P0001948 ! regulation of amide metabolic process [Term] id: CCO:P0001956 name: negative regulation of Rho GTPase activity namespace: biological_process def: "Any process that stops or reduces the rate of activity of a GTPase of the Rho family." [GOC:mah] synonym: "down regulation of Rho GTPase activity" EXACT [] synonym: "down-regulation of Rho GTPase activity" EXACT [] synonym: "downregulation of Rho GTPase activity" EXACT [] synonym: "inhibition of Rho GTPase activity" NARROW [] xref: GO:0034259 is_a: CCO:P0001590 ! regulation of Rho GTPase activity is_a: CCO:P0001957 ! negative regulation of Ras GTPase activity [Term] id: CCO:P0001957 name: negative regulation of Ras GTPase activity namespace: biological_process def: "Any process that stops or reduces the rate of activity of a GTPase of the Ras superfamily." [GOC:mah] synonym: "down regulation of Ras GTPase activity" EXACT [] synonym: "down-regulation of Ras GTPase activity" EXACT [] synonym: "downregulation of Ras GTPase activity" EXACT [] synonym: "inhibition of Ras GTPase activity" NARROW [] xref: GO:0034261 is_a: CCO:P0001589 ! regulation of Ras GTPase activity [Term] id: CCO:P0001958 name: autophagy in response to ER overload namespace: biological_process def: "The process by which cells digest parts of their own cytoplasm in response to the accumulation of misfolded proteins in the endoplasmic reticulum." [GOC:mah] synonym: "autophagy in response to endoplasmic reticulum overload" EXACT [] synonym: "autophagy in response to ER stress" EXACT [] xref: GO:0034263 is_a: CCO:P0000684 ! ER overload response relationship: has_participant CCO:B0058658 ! ATG10_HUMAN [Term] id: CCO:P0001959 name: actinomycete-type spore formation namespace: biological_process def: "The process by which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales." [GOC:ds, ISBN:0122268008] xref: GO:0034304 is_a: CCO:P0001240 ! reproductive process in single-celled organism [Term] id: CCO:P0001960 name: regulation of asexual sporulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis." [GOC:mah] synonym: "regulation of asexual spore formation" EXACT [] synonym: "regulation of mitotic spore formation" EXACT [] synonym: "regulation of mitotic sporulation" EXACT [] xref: GO:0034305 is_a: CCO:P0002048 ! regulation of sporulation [Term] id: CCO:P0001961 name: regulation of sexual sporulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis." [GOC:mah] synonym: "MAPKKK cascade during sporulation (sensu Fungi)" NARROW [] synonym: "regulation of meiotic spore formation" EXACT [] synonym: "regulation of meiotic sporulation" EXACT [] synonym: "regulation of sexual spore formation" EXACT [] xref: GO:0034306 is_a: CCO:P0002048 ! regulation of sporulation [Term] id: CCO:P0001962 name: regulation of ascospore formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ascospore formation." [GOC:mah] synonym: "MAPKKK cascade during sporulation (sensu Saccharomyces)" NARROW [] xref: GO:0034307 is_a: CCO:P0001961 ! regulation of sexual sporulation relationship: regulates CCO:P0001262 ! ascospore formation [Term] id: CCO:P0001963 name: regulation of Arp2/3 complex-mediated actin nucleation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins." [GOC:mah] xref: GO:0034315 is_a: CCO:P0003029 ! regulation of actin nucleation [Term] id: CCO:P0001964 name: negative regulation of Arp2/3 complex-mediated actin nucleation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins." [GOC:mah, PMID:16959963] xref: GO:0034316 is_a: CCO:P0001963 ! regulation of Arp2/3 complex-mediated actin nucleation is_a: CCO:P0003030 ! negative regulation of actin nucleation [Term] id: CCO:P0001965 name: regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor namespace: biological_process def: "Any process by which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:mah, GOC:mh] comment: This term was added by GO_REF:0000021. xref: GO:0034339 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001966 name: regulation of glial cell apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of glial cell apoptosis." [GOC:mah] xref: GO:0034350 is_a: CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:P0001967 name: negative regulation of glial cell apoptosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptosis." [GOC:mah] synonym: "down regulation of glial cell apoptosis" EXACT [] synonym: "down-regulation of glial cell apoptosis" EXACT [] synonym: "downregulation of glial cell apoptosis" EXACT [] synonym: "inhibition of glial cell apoptosis" NARROW [] xref: GO:0034351 is_a: CCO:P0001966 ! regulation of glial cell apoptosis is_a: CCO:P0002148 ! negative regulation of apoptosis [Term] id: CCO:P0001968 name: positive regulation of glial cell apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of glial cell apoptosis." [GOC:mah] synonym: "activation of glial cell apoptosis" NARROW [] synonym: "stimulation of glial cell apoptosis" NARROW [] synonym: "up regulation of glial cell apoptosis" EXACT [] synonym: "up-regulation of glial cell apoptosis" EXACT [] synonym: "upregulation of glial cell apoptosis" EXACT [] xref: GO:0034352 is_a: CCO:P0001966 ! regulation of glial cell apoptosis is_a: CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:P0001969 name: regulation of smooth muscle cell apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptosis." [GOC:rl] synonym: "regulation of SMC apoptosis" EXACT [] xref: GO:0034391 is_a: CCO:P0001042 ! regulation of muscle cell apoptosis [Term] id: CCO:P0001970 name: negative regulation of smooth muscle cell apoptosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptosis." [GOC:rl] synonym: "down regulation of smooth muscle cell apoptosis" EXACT [] synonym: "down-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "downregulation of smooth muscle cell apoptosis" EXACT [] synonym: "inhibition of smooth muscle cell apoptosis" NARROW [] synonym: "negative regulation of SMC apoptosis" EXACT [] xref: GO:0034392 is_a: CCO:P0001041 ! negative regulation of muscle cell apoptosis is_a: CCO:P0001969 ! regulation of smooth muscle cell apoptosis relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN [Term] id: CCO:P0001971 name: positive regulation of smooth muscle cell apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptosis." [GOC:rl] synonym: "activation of smooth muscle cell apoptosis" NARROW [] synonym: "positive regulation of SMC apoptosis" EXACT [] synonym: "stimulation of smooth muscle cell apoptosis" NARROW [] synonym: "up regulation of smooth muscle cell apoptosis" EXACT [] synonym: "up-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "upregulation of smooth muscle cell apoptosis" EXACT [] xref: GO:0034393 is_a: CCO:P0001043 ! positive regulation of muscle cell apoptosis is_a: CCO:P0001969 ! regulation of smooth muscle cell apoptosis relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN [Term] id: CCO:P0001972 name: regulation of transcription from RNA polymerase II promoter in response to iron namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus." [GOC:mah] comment: This term was added by GO_REF:0000021. synonym: "regulation of specific transcription from RNA polymerase II promoter in response to iron" EXACT [] xref: GO:0034395 is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0001973 name: negative regulation of transcription from RNA polymerase II promoter in response to iron namespace: biological_process def: "Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus." [GOC:mah] synonym: "down regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [] synonym: "down-regulation of transcription from RNA polymerase II promoter in response to iron" EXACT [] synonym: "downregulation of transcription from RNA polymerase II promoter in response to iron" EXACT [] synonym: "inhibition of transcription from RNA polymerase II promoter in response to iron" NARROW [] synonym: "negative regulation of transcription from Pol II promoter in response to iron" EXACT [] xref: GO:0034396 is_a: CCO:P0000981 ! negative regulation of specific transcription from RNA polymerase II promoter is_a: CCO:P0001972 ! regulation of transcription from RNA polymerase II promoter in response to iron [Term] id: CCO:P0001974 name: negative regulation of lipoprotein oxidation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation." [GOC:mah] synonym: "inhibition of lipoprotein oxidation" NARROW [] xref: GO:0034443 is_a: CCO:P0002938 ! negative regulation of lipoprotein metabolic process [Term] id: CCO:P0001975 name: negative regulation of plasma lipoprotein oxidation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma." [GOC:mah] synonym: "inhibition of plasma lipoprotein oxidation" NARROW [] xref: GO:0034445 is_a: CCO:P0001974 ! negative regulation of lipoprotein oxidation [Term] id: CCO:P0001976 name: DNA recombinase assembly involved in gene conversion at mating-type locus namespace: biological_process def: "The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another." [GOC:mah] xref: GO:0034624 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000799 ! gene conversion at mating-type locus [Term] id: CCO:P0001977 name: strand invasion involved in gene conversion at mating-type locus namespace: biological_process def: "The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA at the mating-type locus. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This process occurs as part of gene conversion at the mating-type locus." [GOC:mah] xref: GO:0034636 xref: Reactome:76004 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000799 ! gene conversion at mating-type locus [Term] id: CCO:P0001978 name: regulation of melanization defense response namespace: biological_process def: "Any process that affects the rate, extent or location of the melanization defense response during injury or invasion." [GOC:bf] synonym: "regulation of melanization defence response" EXACT [] xref: GO:0035007 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0001979 name: positive regulation of melanization defense response namespace: biological_process def: "Any process that increases the rate or extent of the melanization defense response during injury or invasion." [GOC:bf] synonym: "activation of melanization defense response" NARROW [] synonym: "positive regulation of melanization defence response" EXACT [] synonym: "stimulation of melanization defense response" NARROW [] synonym: "up regulation of melanization defense response" EXACT [] synonym: "up-regulation of melanization defense response" EXACT [] synonym: "upregulation of melanization defense response" EXACT [] xref: GO:0035008 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0001978 ! regulation of melanization defense response [Term] id: CCO:P0001980 name: negative regulation of melanization defense response namespace: biological_process def: "Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection." [GOC:bf, PMID:12408809] synonym: "down regulation of melanization defense response" EXACT [] synonym: "down-regulation of melanization defense response" EXACT [] synonym: "downregulation of melanization defense response" EXACT [] synonym: "inhibition of melanization defense response" NARROW [] synonym: "negative regulation of melanization defence response" EXACT [] xref: GO:0035009 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0001978 ! regulation of melanization defense response [Term] id: CCO:P0001981 name: somatic stem cell maintenance namespace: biological_process def: "The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089] xref: GO:0035019 is_a: CCO:P0001147 ! stem cell maintenance relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN [Term] id: CCO:P0001982 name: regulation of Rac protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Rac protein signal transduction." [GOC:bf] xref: GO:0035020 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: has_participant CCO:B0055616 ! ARF6_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: regulates CCO:P0001131 ! Rac protein signal transduction [Term] id: CCO:P0001983 name: negative regulation of Rac protein signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Rac protein signal transduction." [GOC:bf] synonym: "down regulation of Rac protein signal transduction" EXACT [] synonym: "down-regulation of Rac protein signal transduction" EXACT [] synonym: "downregulation of Rac protein signal transduction" EXACT [] synonym: "inhibition of Rac protein signal transduction" NARROW [] xref: GO:0035021 is_a: CCO:P0001982 ! regulation of Rac protein signal transduction is_a: CCO:P0002700 ! negative regulation of Ras protein signal transduction relationship: has_participant CCO:B0023039 ! STMN3_HUMAN relationship: has_participant CCO:B0024597 ! CEND3_HUMAN relationship: negatively_regulates CCO:P0001131 ! Rac protein signal transduction [Term] id: CCO:P0001984 name: positive regulation of Rac protein signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction." [GOC:bf] synonym: "activation of Rac protein signal transduction" NARROW [] synonym: "stimulation of Rac protein signal transduction" NARROW [] synonym: "up regulation of Rac protein signal transduction" EXACT [] synonym: "up-regulation of Rac protein signal transduction" EXACT [] synonym: "upregulation of Rac protein signal transduction" EXACT [] xref: GO:0035022 is_a: CCO:P0001982 ! regulation of Rac protein signal transduction is_a: CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0058350 ! ALS2_HUMAN relationship: positively_regulates CCO:P0001131 ! Rac protein signal transduction [Term] id: CCO:P0001985 name: regulation of Rho protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Rho protein signal transduction." [GOC:bf] xref: GO:0035023 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction relationship: has_participant CCO:B0002013 ! TITIN_HUMAN relationship: has_participant CCO:B0002023 ! ARHG1_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005645 ! OBSCN_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN relationship: has_participant CCO:B0006123 ! BCR_HUMAN relationship: has_participant CCO:B0006199 ! ITSN2_HUMAN relationship: has_participant CCO:B0019050 ! A6NKB1_HUMAN relationship: has_participant CCO:B0023961 ! Q8NIA3_HUMAN relationship: has_participant CCO:B0027932 ! Q6J1T2_HUMAN relationship: has_participant CCO:B0027933 ! Q6J1T1_HUMAN relationship: has_participant CCO:B0027936 ! Q14BD4_HUMAN relationship: has_participant CCO:B0027945 ! ITSN1_HUMAN relationship: has_participant CCO:B0029042 ! ARHGF_HUMAN relationship: has_participant CCO:B0037015 ! Q1ZYL3_HUMAN relationship: has_participant CCO:B0037017 ! ARHG4_HUMAN relationship: has_participant CCO:B0037018 ! PREX2_HUMAN relationship: has_participant CCO:B0037019 ! SPT13_HUMAN relationship: has_participant CCO:B0037021 ! PREX1_HUMAN relationship: has_participant CCO:B0037023 ! Q5VX68_HUMAN relationship: has_participant CCO:B0037024 ! ARHG9_HUMAN relationship: has_participant CCO:B0037522 ! A2RQD6_HUMAN relationship: has_participant CCO:B0053710 ! YE018_HUMAN relationship: has_participant CCO:B0053712 ! PKHG3_HUMAN relationship: has_participant CCO:B0053822 ! A6NFK4_HUMAN relationship: has_participant CCO:B0053885 ! A6NKJ3_HUMAN relationship: has_participant CCO:B0053991 ! A8MPW5_HUMAN relationship: has_participant CCO:B0053994 ! A8MQ12_HUMAN relationship: has_participant CCO:B0054005 ! A8MS93_HUMAN relationship: has_participant CCO:B0054006 ! A8MSI4_HUMAN relationship: has_participant CCO:B0054036 ! A8MU01_HUMAN relationship: has_participant CCO:B0054062 ! A8MVN0_HUMAN relationship: has_participant CCO:B0054068 ! YB045_HUMAN relationship: has_participant CCO:B0054150 ! A9CQZ6_HUMAN relationship: has_participant CCO:B0054157 ! A9YD18_HUMAN relationship: has_participant CCO:B0054183 ! B0QZD3_HUMAN relationship: has_participant CCO:B0054184 ! B0QZD4_HUMAN relationship: has_participant CCO:B0054235 ! B1AL37_HUMAN relationship: has_participant CCO:B0054239 ! B1ALK7_HUMAN relationship: has_participant CCO:B0054254 ! B1AMR3_HUMAN relationship: has_participant CCO:B0054255 ! B1AMR4_HUMAN relationship: has_participant CCO:B0054381 ! RGRF2_HUMAN relationship: has_participant CCO:B0054397 ! ARHGA_HUMAN relationship: has_participant CCO:B0054403 ! MCF2L_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN relationship: has_participant CCO:B0054534 ! KALRN_HUMAN relationship: has_participant CCO:B0054681 ! TRIO_HUMAN relationship: has_participant CCO:B0054702 ! PKHG5_HUMAN relationship: has_participant CCO:B0054705 ! FARP2_HUMAN relationship: has_participant CCO:B0054981 ! MCF2_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN relationship: has_participant CCO:B0055489 ! VAV2_HUMAN relationship: has_participant CCO:B0055676 ! FGD1_HUMAN relationship: has_participant CCO:B0055682 ! LFDH_HUMAN relationship: has_participant CCO:B0055814 ! Q0MT80_HUMAN relationship: has_participant CCO:B0055839 ! ARHG5_HUMAN relationship: has_participant CCO:B0055843 ! AKP13_HUMAN relationship: has_participant CCO:B0055849 ! Q12843_HUMAN relationship: has_participant CCO:B0055861 ! ABR_HUMAN relationship: has_participant CCO:B0055865 ! TIAM1_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: has_participant CCO:B0055966 ! ARHG7_HUMAN relationship: has_participant CCO:B0056039 ! ARHG6_HUMAN relationship: has_participant CCO:B0056209 ! Q2M269_HUMAN relationship: has_participant CCO:B0056256 ! PKHG6_HUMAN relationship: has_participant CCO:B0056300 ! Q49A55_HUMAN relationship: has_participant CCO:B0056305 ! Q49AN3_HUMAN relationship: has_participant CCO:B0056375 ! PKHG4_HUMAN relationship: has_participant CCO:B0056408 ! Q59GK8_HUMAN relationship: has_participant CCO:B0056436 ! Q5H999_HUMAN relationship: has_participant CCO:B0056480 ! FGD3_HUMAN relationship: has_participant CCO:B0056492 ! Q5JV91_HUMAN relationship: has_participant CCO:B0056493 ! Q5JV94_HUMAN relationship: has_participant CCO:B0056506 ! Q5JYJ2_HUMAN relationship: has_participant CCO:B0056507 ! Q5JYJ3_HUMAN relationship: has_participant CCO:B0056508 ! Q5JYJ5_HUMAN relationship: has_participant CCO:B0056509 ! Q5JYJ6_HUMAN relationship: has_participant CCO:B0056510 ! Q5JYJ7_HUMAN relationship: has_participant CCO:B0056533 ! Q5SQI6_HUMAN relationship: has_participant CCO:B0056544 ! Q5SVK9_HUMAN relationship: has_participant CCO:B0056551 ! Q5SY18_HUMAN relationship: has_participant CCO:B0056552 ! Q5SYV3_HUMAN relationship: has_participant CCO:B0056615 ! Q5TEV0_HUMAN relationship: has_participant CCO:B0056616 ! Q5TEV1_HUMAN relationship: has_participant CCO:B0056657 ! ARHGG_HUMAN relationship: has_participant CCO:B0056666 ! Q5VXI4_HUMAN relationship: has_participant CCO:B0056668 ! Q5VY92_HUMAN relationship: has_participant CCO:B0056669 ! Q5VY93_HUMAN relationship: has_participant CCO:B0056681 ! Q5W9H1_HUMAN relationship: has_participant CCO:B0056707 ! Q68E09_HUMAN relationship: has_participant CCO:B0056867 ! Q6NX52_HUMAN relationship: has_participant CCO:B0056903 ! Q6PFW2_HUMAN relationship: has_participant CCO:B0056930 ! Q6QJE5_HUMAN relationship: has_participant CCO:B0056931 ! Q6QJE6_HUMAN relationship: has_participant CCO:B0056932 ! Q6QJE8_HUMAN relationship: has_participant CCO:B0056933 ! Q6QME9_HUMAN relationship: has_participant CCO:B0056974 ! DNMBP_HUMAN relationship: has_participant CCO:B0057029 ! FGD5_HUMAN relationship: has_participant CCO:B0057037 ! PKHG7_HUMAN relationship: has_participant CCO:B0057060 ! ARHGI_HUMAN relationship: has_participant CCO:B0057065 ! Q6ZT60_HUMAN relationship: has_participant CCO:B0057079 ! Q6ZUZ8_HUMAN relationship: has_participant CCO:B0057083 ! FGD6_HUMAN relationship: has_participant CCO:B0057143 ! Q7Z2K2_HUMAN relationship: has_participant CCO:B0057190 ! ARHG8_HUMAN relationship: has_participant CCO:B0057198 ! FGD2_HUMAN relationship: has_participant CCO:B0057267 ! GEFT_HUMAN relationship: has_participant CCO:B0057310 ! MF2L2_HUMAN relationship: has_participant CCO:B0057328 ! Q8IUU5_HUMAN relationship: has_participant CCO:B0057343 ! TIAM2_HUMAN relationship: has_participant CCO:B0057355 ! ARHGJ_HUMAN relationship: has_participant CCO:B0057433 ! RGNEF_HUMAN relationship: has_participant CCO:B0057467 ! CI100_HUMAN relationship: has_participant CCO:B0057480 ! NGEF_HUMAN relationship: has_participant CCO:B0057924 ! Q8TDA3_HUMAN relationship: has_participant CCO:B0057955 ! SOLO_HUMAN relationship: has_participant CCO:B0058195 ! SGEF_HUMAN relationship: has_participant CCO:B0058279 ! Q96M35_HUMAN relationship: has_participant CCO:B0058282 ! FGD4_HUMAN relationship: has_participant CCO:B0058330 ! ARHGH_HUMAN relationship: has_participant CCO:B0058347 ! PKH4B_HUMAN relationship: has_participant CCO:B0058350 ! ALS2_HUMAN relationship: has_participant CCO:B0058647 ! Q9H023_HUMAN relationship: has_participant CCO:B0058742 ! PKHG2_HUMAN relationship: has_participant CCO:B0058804 ! ARGAL_HUMAN relationship: has_participant CCO:B0058889 ! ARHG3_HUMAN relationship: has_participant CCO:B0058955 ! YD003_HUMAN relationship: has_participant CCO:B0059006 ! ARHGC_HUMAN relationship: has_participant CCO:B0059207 ! VAV3_HUMAN relationship: has_participant CCO:B0059228 ! PKHG1_HUMAN relationship: has_participant CCO:B0059360 ! FARP1_HUMAN relationship: regulates CCO:P0000783 ! Rho protein signal transduction [Term] id: CCO:P0001986 name: negative regulation of Rho protein signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Rho protein signal transduction." [GOC:bf] synonym: "down regulation of Rho protein signal transduction" EXACT [] synonym: "down-regulation of Rho protein signal transduction" EXACT [] synonym: "downregulation of Rho protein signal transduction" EXACT [] synonym: "inhibition of Rho protein signal transduction" NARROW [] xref: GO:0035024 is_a: CCO:P0001985 ! regulation of Rho protein signal transduction is_a: CCO:P0002700 ! negative regulation of Ras protein signal transduction relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0024597 ! CEND3_HUMAN relationship: negatively_regulates CCO:P0000783 ! Rho protein signal transduction [Term] id: CCO:P0001987 name: positive regulation of Rho protein signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction." [GOC:bf] synonym: "activation of Rho protein signal transduction" NARROW [] synonym: "stimulation of Rho protein signal transduction" NARROW [] synonym: "up regulation of Rho protein signal transduction" EXACT [] synonym: "up-regulation of Rho protein signal transduction" EXACT [] synonym: "upregulation of Rho protein signal transduction" EXACT [] xref: GO:0035025 is_a: CCO:P0001985 ! regulation of Rho protein signal transduction is_a: CCO:P0002699 ! positive regulation of Ras protein signal transduction relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0057419 ! ABRA_HUMAN relationship: positively_regulates CCO:P0000783 ! Rho protein signal transduction [Term] id: CCO:P0001988 name: regulation of histone acetylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf] xref: GO:0035065 is_a: CCO:P0001367 ! regulation of histone modification [Term] id: CCO:P0001989 name: positive regulation of histone acetylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf] synonym: "activation of histone acetylation" NARROW [] synonym: "stimulation of histone acetylation" NARROW [] synonym: "up regulation of histone acetylation" EXACT [] synonym: "up-regulation of histone acetylation" EXACT [] synonym: "upregulation of histone acetylation" EXACT [] xref: GO:0035066 is_a: CCO:P0001369 ! positive regulation of histone modification is_a: CCO:P0001988 ! regulation of histone acetylation relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN [Term] id: CCO:P0001990 name: negative regulation of histone acetylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf] synonym: "down regulation of histone acetylation" EXACT [] synonym: "down-regulation of histone acetylation" EXACT [] synonym: "downregulation of histone acetylation" EXACT [] synonym: "inhibition of histone acetylation" NARROW [] xref: GO:0035067 is_a: CCO:P0001368 ! negative regulation of histone modification is_a: CCO:P0001988 ! regulation of histone acetylation relationship: has_participant CCO:B0005519 ! SET_HUMAN [Term] id: CCO:P0001991 name: ecdysone-mediated induction of salivary gland cell autophagic cell death namespace: biological_process def: "Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis." [GOC:bf] synonym: "ecdysone-mediated induction of autophagic cell death of salivary gland cells" EXACT [] synonym: "ecdysone-mediated induction of programmed cell death of salivary gland cells by autophagy" EXACT [] synonym: "ecdysone-mediated induction of salivary gland cell programmed cell death by autophagy" EXACT [] xref: GO:0035072 is_a: CCO:P0001993 ! induction of programmed cell death by ecdysone [Term] id: CCO:P0001992 name: ecdysone receptor-mediated signaling pathway namespace: biological_process def: "The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex." [GOC:bf] synonym: "ecdysone receptor-mediated signalling pathway" EXACT [] xref: GO:0035076 is_a: CCO:P0001278 ! steroid hormone receptor signaling pathway [Term] id: CCO:P0001993 name: induction of programmed cell death by ecdysone namespace: biological_process def: "Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death." [GOC:bf] xref: GO:0035078 is_a: CCO:P0001994 ! induction of programmed cell death by hormones [Term] id: CCO:P0001994 name: induction of programmed cell death by hormones namespace: biological_process def: "Any process induced by hormones that directly activates any of the steps required for programmed cell death." [GOC:bf] xref: GO:0035081 is_a: CCO:P0001050 ! induction of programmed cell death [Term] id: CCO:P0001995 name: RNA interference, siRNA loading onto RISC namespace: biological_process def: "The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC)." [GOC:bf, PMID:14512631] xref: GO:0035087 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001122 ! RNA interference [Term] id: CCO:P0001996 name: sterol regulatory element binding protein cleavage namespace: biological_process def: "The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus and upregulate transcription of target genes, in response to altered levels of one or more lipids." [GOC:bf, PMID:12923525] synonym: "SREBP cleavage" EXACT [] xref: GO:0035103 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001721 ! SREBP-mediated signaling pathway [Term] id: CCO:P0001997 name: positive regulation of sterol regulatory element binding protein target gene transcription namespace: biological_process def: "The process by which a sterol regulatory element binding protein (SREBP) mediates an increase in rate or extent of transcription of nuclear target genes in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs in the promoters of target genes." [GOC:bf, GOC:mah, PMID:12923525] synonym: "activation of sterol regulatory element binding protein target gene transcription" NARROW [] synonym: "SREBP target gene transcriptional activation" EXACT [] synonym: "sterol regulatory element binding protein target gene transcriptional activation" BROAD [] synonym: "stimulation of sterol regulatory element binding protein target gene transcription" NARROW [] synonym: "up regulation of sterol regulatory element binding protein target gene transcription" EXACT [] synonym: "up-regulation of sterol regulatory element binding protein target gene transcription" EXACT [] synonym: "upregulation of sterol regulatory element binding protein target gene transcription" EXACT [] xref: GO:0035104 is_a: CCO:P0000980 ! positive regulation of specific transcription from RNA polymerase II promoter relationship: has_participant CCO:B0056666 ! Q5VXI4_HUMAN relationship: part_of CCO:P0001721 ! SREBP-mediated signaling pathway [Term] id: CCO:P0001998 name: sterol regulatory element binding protein nuclear translocation namespace: biological_process def: "The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes." [GOC:bf, PMID:12923525] synonym: "SREBP nuclear translocation" EXACT [] xref: GO:0035105 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001721 ! SREBP-mediated signaling pathway [Term] id: CCO:P0001999 name: negative regulation of terminal cell fate specification, open tracheal system namespace: biological_process def: "Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates." [GOC:mtg_sensu, PMID:10684581] synonym: "down regulation of terminal cell fate specification" EXACT [] synonym: "down-regulation of terminal cell fate specification" EXACT [] synonym: "downregulation of terminal cell fate specification" EXACT [] synonym: "inhibition of terminal cell fate specification" NARROW [] synonym: "negative regulation of terminal cell fate specification" EXACT [] xref: GO:0035155 is_a: CCO:P0000888 ! negative regulation of cell fate specification [Term] id: CCO:P0002000 name: negative regulation of fusion cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates." [PMID:10684581] synonym: "down regulation of fusion cell fate specification" EXACT [] synonym: "down-regulation of fusion cell fate specification" EXACT [] synonym: "downregulation of fusion cell fate specification" EXACT [] synonym: "inhibition of fusion cell fate specification" NARROW [] xref: GO:0035157 is_a: CCO:P0000888 ! negative regulation of cell fate specification [Term] id: CCO:P0002001 name: hemocyte proliferation namespace: biological_process def: "The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu] synonym: "arthropod blood cell proliferation" EXACT [] synonym: "hemocyte proliferation (sensu Arthropoda)" EXACT [] xref: GO:0035172 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0002002 name: posttranscriptional gene silencing by RNA namespace: biological_process def: "Any process of gene inactivation (silencing) in which small RNAs trigger degradation of mRNA." [PMID:15020054, PMID:15066275, PMID:15066283] synonym: "RNA-mediated posttranscriptional gene silencing" EXACT [GOC:dph, GOC:tb] synonym: "sense-PTGS" RELATED [] xref: GO:0035194 is_a: CCO:P0001123 ! posttranscriptional gene silencing is_a: CCO:P0001363 ! gene silencing by RNA [Term] id: CCO:P0002003 name: gene silencing by miRNA namespace: biological_process def: "Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression." [PMID:14744438, PMID:15066275, PMID:15066283] synonym: "microRNA-mediated gene silencing" EXACT [] synonym: "miRNA-mediated gene silencing" EXACT [GOC:dph, GOC:tb] xref: GO:0035195 is_a: CCO:P0002002 ! posttranscriptional gene silencing by RNA [Term] id: CCO:P0002004 name: gene silencing by miRNA, production of miRNAs namespace: biological_process def: "Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein." [GOC:dph, GOC:tb, PMID:15066275, PMID:15066283] synonym: "microRNA biosynthesis" RELATED [] synonym: "microRNA biosynthetic process" RELATED [] synonym: "microRNA metabolic process" RELATED [] synonym: "microRNA metabolism" RELATED [] synonym: "microRNA processing" BROAD [] synonym: "microRNA-mediated gene silencing, production of microRNAs" EXACT [] synonym: "miRNA processing" EXACT [] synonym: "miRNA-mediated gene silencing, production of miRNAs" EXACT [GOC:dph, GOC:tb] xref: GO:0030918 xref: GO:0035196 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002003 ! gene silencing by miRNA [Term] id: CCO:P0002005 name: regulation of lamellocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104] xref: GO:0035203 is_a: CCO:P0002424 ! regulation of hemocyte differentiation [Term] id: CCO:P0002006 name: negative regulation of lamellocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104] synonym: "down regulation of lamellocyte differentiation" EXACT [] synonym: "down-regulation of lamellocyte differentiation" EXACT [] synonym: "downregulation of lamellocyte differentiation" EXACT [] synonym: "inhibition of lamellocyte differentiation" NARROW [] xref: GO:0035204 is_a: CCO:P0002005 ! regulation of lamellocyte differentiation is_a: CCO:P0002425 ! negative regulation of hemocyte differentiation [Term] id: CCO:P0002007 name: positive regulation of lamellocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [PMID:14734104] synonym: "activation of lamellocyte differentiation" NARROW [] synonym: "stimulation of lamellocyte differentiation" NARROW [] synonym: "up regulation of lamellocyte differentiation" EXACT [] synonym: "up-regulation of lamellocyte differentiation" EXACT [] synonym: "upregulation of lamellocyte differentiation" EXACT [] xref: GO:0035205 is_a: CCO:P0002005 ! regulation of lamellocyte differentiation is_a: CCO:P0002426 ! positive regulation of hemocyte differentiation [Term] id: CCO:P0002008 name: regulation of hemocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu] synonym: "regulation of arthropod blood cell proliferation" EXACT [] synonym: "regulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] xref: GO:0035206 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0002001 ! hemocyte proliferation [Term] id: CCO:P0002009 name: negative regulation of hemocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu] synonym: "down regulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] synonym: "down-regulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] synonym: "downregulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] synonym: "inhibition of hemocyte proliferation (sensu Arthropoda)" NARROW [] synonym: "negative regulation of arthropod blood cell proliferation" EXACT [] synonym: "negative regulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] xref: GO:0035207 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0002008 ! regulation of hemocyte proliferation relationship: negatively_regulates CCO:P0002001 ! hemocyte proliferation [Term] id: CCO:P0002010 name: positive regulation of hemocyte proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu] synonym: "activation of hemocyte proliferation (sensu Arthropoda)" NARROW [] synonym: "positive regulation of arthropod blood cell proliferation" EXACT [] synonym: "positive regulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] synonym: "stimulation of hemocyte proliferation (sensu Arthropoda)" NARROW [] synonym: "up regulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] synonym: "up-regulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] synonym: "upregulation of hemocyte proliferation (sensu Arthropoda)" EXACT [] xref: GO:0035208 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0002008 ! regulation of hemocyte proliferation relationship: positively_regulates CCO:P0002001 ! hemocyte proliferation [Term] id: CCO:P0002011 name: ionotropic glutamate receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor, followed by the movement of ions through a channel in the receptor complex." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] synonym: "ionotropic glutamate receptor signalling pathway" EXACT [] xref: GO:0035235 is_a: CCO:P0000750 ! glutamate signaling pathway relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN relationship: has_participant CCO:B0055016 ! AT1A3_HUMAN relationship: has_participant CCO:B0055744 ! NMDZ1_HUMAN [Term] id: CCO:P0002012 name: gene silencing by miRNA, negative regulation of translation namespace: biological_process def: "The process by which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs." [PMID:14744438, PMID:15196554] synonym: "miRNA-mediated gene silencing, down regulation of translation" EXACT [] synonym: "miRNA-mediated gene silencing, down-regulation of translation" EXACT [] synonym: "miRNA-mediated gene silencing, downregulation of translation" EXACT [] synonym: "miRNA-mediated gene silencing, inhibition of translation" NARROW [] synonym: "miRNA-mediated gene silencing, negative regulation of translation" RELATED [GOC:dph, GOC:tb] xref: GO:0035278 is_a: CCO:P0002025 ! negative regulation of translation, ncRNA-mediated relationship: part_of CCO:P0002003 ! gene silencing by miRNA [Term] id: CCO:P0002013 name: gene silencing by miRNA, mRNA cleavage namespace: biological_process def: "The process by which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically direct cleavage by base pairing with near-perfect complementarity to the target mRNA. Many plant miRNAs downregulate gene expression through this mechanism." [GOC:dph, GOC:mtg_lung, PMID:14744438, PMID:15196554] synonym: "miRNA-mediated gene silencing, mRNA cleavage" EXACT [GOC:dph, GOC:tb] xref: GO:0035279 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002003 ! gene silencing by miRNA [Term] id: CCO:P0002014 name: gene silencing by miRNA, miRNA loading onto RISC namespace: biological_process def: "The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC)." [PMID:14744438] synonym: "miRISC assembly" BROAD [] synonym: "miRNA-mediated gene silencing, miRNA loading onto RISC" EXACT [GOC:dph, GOC:tb] xref: GO:0035280 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002003 ! gene silencing by miRNA [Term] id: CCO:P0002015 name: pre-microRNA export from nucleus namespace: biological_process def: "Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product." [PMID:14744438] synonym: "pre-microRNA export from cell nucleus" EXACT [] synonym: "pre-microRNA export out of nucleus" EXACT [] synonym: "pre-microRNA transport from nucleus to cytoplasm" EXACT [] synonym: "pre-microRNA-nucleus export" EXACT [] xref: GO:0035281 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002003 ! gene silencing by miRNA [Term] id: CCO:P0002016 name: regulation of dephosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf] subset: gosubset_prok xref: GO:0035303 is_a: CCO:P0001143 ! regulation of phosphate metabolic process relationship: has_participant CCO:B0057255 ! EST1A_HUMAN relationship: has_participant CCO:B0058061 ! SMG7_HUMAN relationship: has_participant CCO:B0059266 ! SMG5_HUMAN [Term] id: CCO:P0002017 name: regulation of protein amino acid dephosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf] subset: gosubset_prok xref: GO:0035304 is_a: CCO:P0001433 ! regulation of protein modification process is_a: CCO:P0002016 ! regulation of dephosphorylation [Term] id: CCO:P0002018 name: negative regulation of dephosphorylation namespace: biological_process def: "Any process the stops, prevents or reduces the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf] subset: gosubset_prok synonym: "down regulation of dephosphorylation" EXACT [] synonym: "down-regulation of dephosphorylation" EXACT [] synonym: "downregulation of dephosphorylation" EXACT [] synonym: "inhibition of dephosphorylation" NARROW [] xref: GO:0035305 is_a: CCO:P0002016 ! regulation of dephosphorylation is_a: CCO:P0002621 ! negative regulation of phosphate metabolic process [Term] id: CCO:P0002019 name: positive regulation of dephosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule." [GOC:bf] subset: gosubset_prok synonym: "activation of dephosphorylation" NARROW [] synonym: "stimulation of dephosphorylation" NARROW [] synonym: "up regulation of dephosphorylation" EXACT [] synonym: "up-regulation of dephosphorylation" EXACT [] synonym: "upregulation of dephosphorylation" EXACT [] xref: GO:0035306 is_a: CCO:P0002016 ! regulation of dephosphorylation is_a: CCO:P0002622 ! positive regulation of phosphate metabolic process [Term] id: CCO:P0002020 name: positive regulation of protein amino acid dephosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf] subset: gosubset_prok synonym: "activation of protein amino acid dephosphorylation" NARROW [] synonym: "stimulation of protein amino acid dephosphorylation" NARROW [] synonym: "up regulation of protein amino acid dephosphorylation" EXACT [] synonym: "up-regulation of protein amino acid dephosphorylation" EXACT [] synonym: "upregulation of protein amino acid dephosphorylation" EXACT [] xref: GO:0035307 is_a: CCO:P0001435 ! positive regulation of protein modification process is_a: CCO:P0002017 ! regulation of protein amino acid dephosphorylation is_a: CCO:P0002019 ! positive regulation of dephosphorylation relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN relationship: has_participant CCO:B0025635 ! PTPA_HUMAN [Term] id: CCO:P0002021 name: negative regulation of protein amino acid dephosphorylation namespace: biological_process def: "Any process the stops, prevents or reduces the frequency, rate or extent of removal of phosphate groups from a protein." [GOC:bf] subset: gosubset_prok synonym: "down regulation of protein amino acid dephosphorylation" EXACT [] synonym: "down-regulation of protein amino acid dephosphorylation" EXACT [] synonym: "downregulation of protein amino acid dephosphorylation" EXACT [] synonym: "inhibition of protein amino acid dephosphorylation" NARROW [] xref: GO:0035308 is_a: CCO:P0001434 ! negative regulation of protein modification process is_a: CCO:P0002017 ! regulation of protein amino acid dephosphorylation is_a: CCO:P0002018 ! negative regulation of dephosphorylation relationship: has_participant CCO:B0025635 ! PTPA_HUMAN [Term] id: CCO:P0002022 name: embryonic cleavage namespace: biological_process def: "The first few specialized divisions of an activated animal egg." [GOC:clt, ISBN:0070524300] xref: GO:0040016 is_a: CCO:P0003077 ! cell division relationship: has_participant CCO:B0001610 ! PK3CB_HUMAN [Term] id: CCO:P0002023 name: regulation of gene expression, epigenetic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence." [PMID:10521337, PMID:11498582] subset: goslim_generic subset: goslim_plant subset: gosubset_prok xref: GO:0040029 is_a: CCO:P0000947 ! regulation of gene expression relationship: has_participant CCO:B0054910 ! GPX1_HUMAN relationship: has_participant CCO:B0058117 ! GLMN_HUMAN [Term] id: CCO:P0002024 name: regulation of molecular function, epigenetic namespace: biological_process def: "Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:ems, GOC:tb, PMID:10611975, PMID:11050225, PMID:11447696, PMID:11685242, PMID:11782551] synonym: "regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb] xref: GO:0040030 is_a: CCO:P0002023 ! regulation of gene expression, epigenetic [Term] id: CCO:P0002025 name: negative regulation of translation, ncRNA-mediated namespace: biological_process def: "Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein." [GOC:dph, GOC:ems, GOC:tb] synonym: "down regulation of mRNA translation, ncRNA-mediated" EXACT [] synonym: "down-regulation of mRNA translation, ncRNA-mediated" EXACT [] synonym: "downregulation of mRNA translation, ncRNA-mediated" EXACT [] synonym: "inhibition of mRNA translation, ncRNA-mediated" NARROW [] xref: GO:0040033 is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0002652 ! regulation of translation, ncRNA-mediated [Term] id: CCO:P0002026 name: regulation of fibroblast growth factor receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity." [GOC:go_curators] synonym: "regulation of FGF receptor signaling pathway" EXACT [] synonym: "regulation of FGF receptor signalling pathway" EXACT [] synonym: "regulation of FGFR signaling pathway" EXACT [] xref: GO:0040036 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0015164 ! HHIP_HUMAN relationship: has_participant CCO:B0055255 ! OTX2_HUMAN relationship: regulates CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:P0002027 name: negative regulation of fibroblast growth factor receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity." [GOC:go_curators] synonym: "down regulation of fibroblast growth factor receptor signaling pathway" EXACT [] synonym: "down-regulation of fibroblast growth factor receptor signaling pathway" EXACT [] synonym: "downregulation of fibroblast growth factor receptor signaling pathway" EXACT [] synonym: "inhibition of fibroblast growth factor receptor signaling pathway" NARROW [] synonym: "negative regulation of FGF receptor signaling pathway" EXACT [] synonym: "negative regulation of FGF receptor signalling pathway" EXACT [] synonym: "negative regulation of FGFR signaling pathway" EXACT [] xref: GO:0040037 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002026 ! regulation of fibroblast growth factor receptor signaling pathway relationship: negatively_regulates CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:P0002028 name: DNA endoreduplication namespace: biological_process def: "Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. For example, occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes." [GOC:jl] comment: Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states. subset: gosubset_prok synonym: "DNA endoreplication" EXACT [] synonym: "DNA re-duplication" EXACT [] xref: GO:0042023 is_a: CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0002029 name: DNA endoreduplication initiation namespace: biological_process def: "The reinitiation of DNA replication within a single cell cycle." [GOC:jl] subset: gosubset_prok synonym: "DNA re-replication initiation" EXACT [] xref: GO:0042024 is_a: CCO:P0000634 ! DNA replication initiation [Term] id: CCO:P0002030 name: regulation of cytokine biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines." [GOC:go_curators] synonym: "regulation of cytokine anabolism" EXACT [] synonym: "regulation of cytokine biosynthesis" EXACT [] synonym: "regulation of cytokine formation" EXACT [] synonym: "regulation of cytokine synthesis" EXACT [] xref: GO:0042035 is_a: CCO:P0001404 ! regulation of cellular metabolic process relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0054319 ! IF2B3_HUMAN relationship: has_participant CCO:B0055166 ! GATA3_HUMAN relationship: has_participant CCO:B0058790 ! ZN287_HUMAN relationship: has_participant CCO:B0059000 ! IF2B1_HUMAN relationship: has_participant CCO:B0059410 ! IF2B2_HUMAN [Term] id: CCO:P0002031 name: negative regulation of cytokine biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines." [GOC:go_curators] synonym: "down regulation of cytokine biosynthetic process" EXACT [] synonym: "down-regulation of cytokine biosynthetic process" EXACT [] synonym: "downregulation of cytokine biosynthetic process" EXACT [] synonym: "inhibition of cytokine biosynthetic process" NARROW [] synonym: "negative regulation of cytokine anabolism" EXACT [] synonym: "negative regulation of cytokine biosynthesis" EXACT [] synonym: "negative regulation of cytokine formation" EXACT [] synonym: "negative regulation of cytokine synthesis" EXACT [] xref: GO:0042036 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: has_participant CCO:B0057954 ! RN128_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN relationship: has_participant CCO:B0059373 ! ASB1_HUMAN [Term] id: CCO:P0002032 name: regulation of dopamine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." [GOC:go_curators] synonym: "regulation of dopamine metabolism" EXACT [] xref: GO:0042053 is_a: CCO:P0002037 ! regulation of catecholamine metabolic process relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN relationship: has_participant CCO:B0055363 ! NR4A2_HUMAN relationship: has_participant CCO:B0055697 ! SC6A3_HUMAN [Term] id: CCO:P0002033 name: regulation of epidermal growth factor receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] synonym: "regulation of EGF receptor signaling pathway" EXACT [] synonym: "regulation of EGF receptor signalling pathway" EXACT [] synonym: "regulation of EGFR signaling pathway" EXACT [] xref: GO:0042058 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: regulates CCO:P0000715 ! epidermal growth factor receptor signaling pathway [Term] id: CCO:P0002034 name: negative regulation of epidermal growth factor receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] synonym: "down regulation of epidermal growth factor receptor signaling pathway" EXACT [] synonym: "down-regulation of epidermal growth factor receptor signaling pathway" EXACT [] synonym: "downregulation of epidermal growth factor receptor signaling pathway" EXACT [] synonym: "inhibition of epidermal growth factor receptor signaling pathway" NARROW [] synonym: "negative regulation of EGF receptor signaling pathway" EXACT [] synonym: "negative regulation of EGF receptor signalling pathway" EXACT [] synonym: "negative regulation of EGFR signaling pathway" EXACT [] xref: GO:0042059 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002033 ! regulation of epidermal growth factor receptor signaling pathway relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: negatively_regulates CCO:P0000715 ! epidermal growth factor receptor signaling pathway [Term] id: CCO:P0002035 name: long-term strengthening of neuromuscular junction namespace: biological_process def: "Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse." [GOC:mtg_15jun06_ch] comment: This term was added by GO_REF:0000021. xref: GO:0042062 is_a: CCO:P0002960 ! positive regulation of synaptic transmission relationship: has_participant CCO:B0055509 ! CO4A4_HUMAN relationship: part_of CCO:P0000824 ! regulation of synaptic growth at neuromuscular junction [Term] id: CCO:P0002036 name: regulation of pteridine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of pteridine metabolism" EXACT [] xref: GO:0042068 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0002037 name: regulation of catecholamine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of catecholamine metabolism" EXACT [] xref: GO:0042069 is_a: CCO:P0001817 ! regulation of amine metabolic process [Term] id: CCO:P0002038 name: germ-line stem cell division namespace: biological_process def: "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jic, PMID:2279698] synonym: "germ-line stem cell renewal" EXACT [] xref: GO:0042078 xref: GO:0048131 is_a: CCO:P0000821 ! asymmetric cell division is_a: CCO:P0001134 ! stem cell division [Term] id: CCO:P0002039 name: T cell proliferation namespace: biological_process def: "The expansion of a T cell population by cell division. Follows T cell activation." [GOC:jl] synonym: "T lymphocyte proliferation" EXACT [] synonym: "T-cell proliferation" EXACT [] synonym: "T-lymphocyte proliferation" EXACT [] xref: GO:0042098 xref: GO:0042111 is_a: CCO:P0002724 ! lymphocyte proliferation relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0054490 ! TNF14_HUMAN relationship: has_participant CCO:B0055603 ! CXCR4_HUMAN [Term] id: CCO:P0002040 name: B cell proliferation namespace: biological_process def: "The expansion of a B cell population by cell division. Follows B cell activation." [GOC:jl] synonym: "B lymphocyte proliferation" EXACT [] synonym: "B-cell proliferation" EXACT [] synonym: "B-lymphocyte proliferation" EXACT [] xref: GO:0042100 xref: GO:0042114 is_a: CCO:P0002724 ! lymphocyte proliferation relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0015966 ! IFNB_HUMAN relationship: has_participant CCO:B0050340 ! CD40L_HUMAN relationship: has_participant CCO:B0054996 ! CD79A_HUMAN relationship: has_participant CCO:B0055142 ! IL10_HUMAN relationship: has_participant CCO:B0055188 ! TNR5_HUMAN [Term] id: CCO:P0002041 name: positive regulation of T cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of T cell proliferation." [GOC:ai] synonym: "activation of T cell proliferation" NARROW [] synonym: "positive regulation of T lymphocyte proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte proliferation" EXACT [] synonym: "stimulation of T cell proliferation" NARROW [] synonym: "up regulation of T cell proliferation" EXACT [] synonym: "up-regulation of T cell proliferation" EXACT [] synonym: "upregulation of T cell proliferation" EXACT [] xref: GO:0042102 is_a: CCO:P0002046 ! regulation of T cell proliferation is_a: CCO:P0002915 ! positive regulation of lymphocyte proliferation is_a: CCO:P0002988 ! positive regulation of T cell activation relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0001508 ! CD28_HUMAN relationship: has_participant CCO:B0001927 ! Q70WG0_HUMAN relationship: has_participant CCO:B0005815 ! EFNB1_HUMAN relationship: has_participant CCO:B0006097 ! PNPH_HUMAN relationship: has_participant CCO:B0054506 ! NCK2_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0054916 ! CD3E_HUMAN relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055048 ! NCK1_HUMAN relationship: has_participant CCO:B0055107 ! VCAM1_HUMAN relationship: has_participant CCO:B0056685 ! CD276_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN relationship: has_participant CCO:B0058783 ! IL21_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN relationship: positively_regulates CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0002042 name: positive regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of resting T cell proliferation." [GOC:jl] synonym: "activation of T cell homeostatic proliferation" NARROW [] synonym: "positive regulation of resting T cell proliferation" EXACT [] synonym: "positive regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "positive regulation of T-cell homeostatic proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte homeostatic proliferation" EXACT [] synonym: "stimulation of T cell homeostatic proliferation" NARROW [] synonym: "up regulation of T cell homeostatic proliferation" EXACT [] synonym: "up-regulation of T cell homeostatic proliferation" EXACT [] synonym: "upregulation of T cell homeostatic proliferation" EXACT [] xref: GO:0042103 is_a: CCO:P0002041 ! positive regulation of T cell proliferation is_a: CCO:P0002675 ! regulation of T cell homeostatic proliferation relationship: positively_regulates CCO:P0000470 ! T cell homeostatic proliferation [Term] id: CCO:P0002043 name: positive regulation of activated T cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of activated T cell proliferation." [GOC:jl] synonym: "activation of activated T cell proliferation" NARROW [] synonym: "positive regulation of activated T lymphocyte proliferation" EXACT [] synonym: "positive regulation of activated T-cell proliferation" EXACT [] synonym: "positive regulation of activated T-lymphocyte proliferation" EXACT [] synonym: "stimulation of activated T cell proliferation" NARROW [] synonym: "up regulation of activated T cell proliferation" EXACT [] synonym: "up-regulation of activated T cell proliferation" EXACT [] synonym: "upregulation of activated T cell proliferation" EXACT [] xref: GO:0042104 is_a: CCO:P0002041 ! positive regulation of T cell proliferation is_a: CCO:P0002671 ! regulation of activated T cell proliferation relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0054605 ! ICOSL_HUMAN relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: has_participant CCO:B0055957 ! IL18_HUMAN relationship: positively_regulates CCO:P0002957 ! activated T cell proliferation [Term] id: CCO:P0002044 name: positive regulation of cytokine biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines." [GOC:go_curators] synonym: "activation of cytokine biosynthetic process" NARROW [] synonym: "positive regulation of cytokine anabolism" EXACT [] synonym: "positive regulation of cytokine biosynthesis" EXACT [] synonym: "positive regulation of cytokine formation" EXACT [] synonym: "positive regulation of cytokine synthesis" EXACT [] synonym: "stimulation of cytokine biosynthetic process" NARROW [] synonym: "up regulation of cytokine biosynthetic process" EXACT [] synonym: "up-regulation of cytokine biosynthetic process" EXACT [] synonym: "upregulation of cytokine biosynthetic process" EXACT [] xref: GO:0042108 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: has_participant CCO:B0001362 ! EREG_HUMAN [Term] id: CCO:P0002045 name: regulation of cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] subset: gosubset_prok xref: GO:0042127 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001479 ! ANXA1_HUMAN relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001767 ! BMPR2_HUMAN relationship: has_participant CCO:B0001817 ! E2F4_HUMAN relationship: has_participant CCO:B0001904 ! KCD11_HUMAN relationship: has_participant CCO:B0002060 ! NEB2_HUMAN relationship: has_participant CCO:B0002103 ! GNL3_HUMAN relationship: has_participant CCO:B0002245 ! JAG2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0016881 ! FOXO1_HUMAN relationship: has_participant CCO:B0028290 ! JAG1_HUMAN relationship: has_participant CCO:B0029685 ! STAT6_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0036805 ! PDX1_HUMAN relationship: has_participant CCO:B0042178 ! MAFG_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: has_participant CCO:B0054463 ! RBM9_HUMAN relationship: has_participant CCO:B0055222 ! GRPR_HUMAN relationship: has_participant CCO:B0055223 ! AGTR1_HUMAN relationship: has_participant CCO:B0055292 ! HXD13_HUMAN relationship: has_participant CCO:B0055403 ! SOX9_HUMAN relationship: has_participant CCO:B0055834 ! DBP_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056278 ! GRDN_HUMAN relationship: has_participant CCO:B0057241 ! Q86TP4_HUMAN relationship: has_participant CCO:B0057490 ! EID2_HUMAN relationship: has_participant CCO:B0057924 ! Q8TDA3_HUMAN relationship: has_participant CCO:B0058356 ! SG3A1_HUMAN relationship: has_participant CCO:B0058357 ! ARX_HUMAN relationship: has_participant CCO:B0058536 ! CDCA7_HUMAN relationship: has_participant CCO:B0058578 ! ACE2_HUMAN relationship: has_participant CCO:B0058646 ! ACH10_HUMAN relationship: has_participant CCO:B0059078 ! DHCR7_HUMAN relationship: has_participant CCO:B0059107 ! CFDP1_HUMAN relationship: has_participant CCO:B0059217 ! TCFL5_HUMAN relationship: regulates CCO:P0000815 ! cell proliferation [Term] id: CCO:P0002046 name: regulation of T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell proliferation." [GOC:jl] synonym: "regulation of T lymphocyte proliferation" EXACT [] synonym: "regulation of T-cell proliferation" EXACT [] synonym: "regulation of T-lymphocyte proliferation" EXACT [] xref: GO:0042129 is_a: CCO:P0002914 ! regulation of lymphocyte proliferation is_a: CCO:P0002981 ! regulation of T cell activation relationship: has_participant CCO:B0057596 ! IL27A_HUMAN relationship: regulates CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0002047 name: negative regulation of T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." [GOC:jl] synonym: "down regulation of T cell proliferation" EXACT [] synonym: "down-regulation of T cell proliferation" EXACT [] synonym: "downregulation of T cell proliferation" EXACT [] synonym: "inhibition of T cell proliferation" NARROW [] synonym: "negative regulation of T lymphocyte proliferation" EXACT [] synonym: "negative regulation of T-cell proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte proliferation" EXACT [] xref: GO:0042130 is_a: CCO:P0002046 ! regulation of T cell proliferation is_a: CCO:P0002916 ! negative regulation of lymphocyte proliferation is_a: CCO:P0002986 ! negative regulation of T cell activation relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055142 ! IL10_HUMAN relationship: has_participant CCO:B0055282 ! SFTPD_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0058117 ! GLMN_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN relationship: has_participant CCO:B0059011 ! PD1L1_HUMAN relationship: has_participant CCO:B0059297 ! VSIG4_HUMAN relationship: negatively_regulates CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0002048 name: regulation of sporulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of spore formation." [GOC:jl] subset: gosubset_prok xref: GO:0042173 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002049 name: negative regulation of sporulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sporulation." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of sporulation" EXACT [] synonym: "down-regulation of sporulation" EXACT [] synonym: "downregulation of sporulation" EXACT [] synonym: "inhibition of sporulation" NARROW [] xref: GO:0042174 is_a: CCO:P0002048 ! regulation of sporulation is_a: CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:P0002050 name: natural killer cell mediated cytotoxicity namespace: biological_process def: "The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add] comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell. synonym: "killer activity" RELATED [] synonym: "natural killer cell mediated cell death" EXACT [] synonym: "natural killer cell mediated cell killing" EXACT [] synonym: "natural killer cell mediated cytolysis" RELATED [] synonym: "natural killer-cell mediated cytolysis" RELATED [] synonym: "NK cell mediated cell death" EXACT [] synonym: "NK cell mediated cell killing" EXACT [] synonym: "NK cell mediated cytolysis" RELATED [] synonym: "NK cell mediated cytotoxicity" EXACT [] xref: GO:0042267 is_a: CCO:P0000672 ! induction of apoptosis relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN relationship: has_participant CCO:B0005727 ! TBB5_HUMAN relationship: has_participant CCO:B0019878 ! TBB2C_HUMAN relationship: has_participant CCO:B0058442 ! LYST_HUMAN relationship: has_participant CCO:B0058858 ! SLAF7_HUMAN [Term] id: CCO:P0002051 name: regulation of cytolysis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm." [GOC:jl] subset: gosubset_prok xref: GO:0042268 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0002052 name: regulation of natural killer cell mediated cytotoxicity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of natural killer cell mediated cell death" EXACT [] synonym: "regulation of natural killer cell mediated cell killing" EXACT [] synonym: "regulation of natural killer cell mediated cytolysis" RELATED [] synonym: "regulation of natural killer-cell mediated cytolysis" RELATED [] synonym: "regulation of NK cell mediated cell death" EXACT [] synonym: "regulation of NK cell mediated cell killing" EXACT [] synonym: "regulation of NK cell mediated cytolysis" RELATED [] synonym: "regulation of NK cell mediated cytotoxicity" RELATED [] xref: GO:0042269 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0054688 ! NCTR1_HUMAN relationship: regulates CCO:P0002050 ! natural killer cell mediated cytotoxicity [Term] id: CCO:P0002053 name: protection from natural killer cell mediated cytotoxicity namespace: biological_process def: "The process of protecting a cell from natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "protection from natural killer cell mediated cell death" EXACT [] synonym: "protection from natural killer cell mediated cell killing" EXACT [] synonym: "protection from natural killer cell mediated cytolysis" RELATED [] synonym: "protection from NK cell mediated cell death" EXACT [] synonym: "protection from NK cell mediated cell killing" EXACT [] synonym: "protection from NK cell mediated cytolysis" RELATED [] synonym: "protection from NK cell mediated cytotoxicity" EXACT [] xref: GO:0042270 is_a: CCO:P0002636 ! negative regulation of natural killer cell mediated cytotoxicity [Term] id: CCO:P0002054 name: susceptibility to natural killer cell mediated cytotoxicity namespace: biological_process def: "The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] comment: Note that this term is intended for cell-surface molecules on a target cell which interact with activating receptors on a natural killer cell to promote natural killer cell mediated cytotoxicity. synonym: "susceptibility to natural killer cell mediated cell death" EXACT [] synonym: "susceptibility to natural killer cell mediated cell killing" EXACT [] synonym: "susceptibility to natural killer cell mediated cytolysis" RELATED [] synonym: "susceptibility to NK cell mediated cell death" EXACT [] synonym: "susceptibility to NK cell mediated cell killing" EXACT [] synonym: "susceptibility to NK cell mediated cytolysis" EXACT [] synonym: "susceptibility to NK cell mediated cytotoxicity" EXACT [] xref: GO:0042271 is_a: CCO:P0002637 ! positive regulation of natural killer cell mediated cytotoxicity relationship: has_participant CCO:B0002110 ! CADM1_HUMAN [Term] id: CCO:P0002055 name: regulation of fatty acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils." [GOC:go_curators, GOC:jl] subset: gosubset_prok synonym: "regulation of fatty acid anabolism" EXACT [] synonym: "regulation of fatty acid biosynthesis" EXACT [] synonym: "regulation of fatty acid formation" EXACT [] synonym: "regulation of fatty acid synthesis" EXACT [] xref: GO:0042304 xref: Reactome:163680 xref: Reactome:211646 xref: Reactome:221418 xref: Reactome:230053 xref: Reactome:238071 xref: Reactome:244683 xref: Reactome:249611 xref: Reactome:252409 xref: Reactome:255568 xref: Reactome:258941 xref: Reactome:262316 xref: Reactome:265166 xref: Reactome:268292 xref: Reactome:273973 xref: Reactome:280452 xref: Reactome:286474 is_a: CCO:P0001140 ! regulation of fatty acid metabolic process is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0002056 name: protein kinase C deactivation namespace: biological_process def: "Any process resulting in the inhibition or termination of the activity of protein kinase C." [GOC:bf] synonym: "PKC deactivation" EXACT [] xref: GO:0042313 is_a: CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: has_participant CCO:B0043822 ! EDN1_HUMAN [Term] id: CCO:P0002057 name: regulation of phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl] subset: gosubset_prok xref: GO:0042325 is_a: CCO:P0001143 ! regulation of phosphate metabolic process relationship: has_participant CCO:B0001441 ! RAD17_HUMAN relationship: has_participant CCO:B0001589 ! MCM7_HUMAN relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0005716 ! PSN1_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: has_participant CCO:B0057117 ! Q7L3H5_HUMAN relationship: has_participant CCO:B0057886 ! PP14C_HUMAN relationship: has_participant CCO:B0058145 ! PP14A_HUMAN relationship: has_participant CCO:B0058179 ! PP14B_HUMAN relationship: has_participant CCO:B0058953 ! PP14D_HUMAN [Term] id: CCO:P0002058 name: negative regulation of phosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl] subset: gosubset_prok synonym: "down regulation of phosphorylation" EXACT [] synonym: "down-regulation of phosphorylation" EXACT [] synonym: "downregulation of phosphorylation" EXACT [] synonym: "inhibition of phosphorylation" NARROW [] xref: GO:0042326 is_a: CCO:P0002057 ! regulation of phosphorylation is_a: CCO:P0002621 ! negative regulation of phosphate metabolic process relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001615 ! CD2A1_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001617 ! CDN2C_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0006226 ! DYL1_HUMAN [Term] id: CCO:P0002059 name: positive regulation of phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." [GOC:jl] subset: gosubset_prok synonym: "activation of phosphorylation" NARROW [] synonym: "stimulation of phosphorylation" NARROW [] synonym: "up regulation of phosphorylation" EXACT [] synonym: "up-regulation of phosphorylation" EXACT [] synonym: "upregulation of phosphorylation" EXACT [] xref: GO:0042327 is_a: CCO:P0002057 ! regulation of phosphorylation is_a: CCO:P0002622 ! positive regulation of phosphate metabolic process relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN relationship: has_participant CCO:B0058117 ! GLMN_HUMAN [Term] id: CCO:P0002060 name: gibberellic acid mediated signaling, G-alpha-dependent namespace: biological_process def: "A series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors." [GOC:pj, PMID:11027362] synonym: "gibberellic acid mediated signalling, G-alpha-dependent" EXACT [] xref: GO:0042388 is_a: CCO:P0000856 ! gibberellic acid mediated signaling [Term] id: CCO:P0002061 name: gibberellic acid mediated signaling, G-alpha-independent namespace: biological_process def: "A series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors." [GOC:pj, PMID:11027362] synonym: "gibberellic acid mediated signalling, G-alpha-independent" EXACT [] xref: GO:0042390 is_a: CCO:P0000856 ! gibberellic acid mediated signaling [Term] id: CCO:P0002062 name: dosage compensation, by hypoactivation of X chromosome namespace: biological_process def: "Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes." [GOC:jl, PMID:11102361] synonym: "dosage compensation (sensu Nematoda)" EXACT [] xref: GO:0042464 is_a: CCO:P0000803 ! dosage compensation [Term] id: CCO:P0002063 name: regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "regulation of eye photoreceptor development" EXACT [] xref: GO:0042478 is_a: CCO:P0001241 ! regulation of cell morphogenesis [Term] id: CCO:P0002064 name: positive regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "activation of eye photoreceptor cell development" NARROW [] synonym: "positive regulation of eye photoreceptor development" EXACT [] synonym: "stimulation of eye photoreceptor cell development" NARROW [] synonym: "up regulation of eye photoreceptor cell development" EXACT [] synonym: "up-regulation of eye photoreceptor cell development" EXACT [] synonym: "upregulation of eye photoreceptor cell development" EXACT [] xref: GO:0042479 is_a: CCO:P0002063 ! regulation of eye photoreceptor cell development is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis [Term] id: CCO:P0002065 name: negative regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "down regulation of eye photoreceptor cell development" EXACT [] synonym: "down-regulation of eye photoreceptor cell development" EXACT [] synonym: "downregulation of eye photoreceptor cell development" EXACT [] synonym: "inhibition of eye photoreceptor cell development" NARROW [] synonym: "negative regulation of eye photoreceptor development" EXACT [] xref: GO:0042480 is_a: CCO:P0002063 ! regulation of eye photoreceptor cell development is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis [Term] id: CCO:P0002066 name: serine phosphorylation of STAT protein namespace: biological_process def: "The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:10918594] xref: GO:0042501 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0002067 name: tyrosine phosphorylation of Stat2 protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a Stat2 protein." [GOC:jl, PMID:10918594] xref: GO:0042502 is_a: CCO:P0000777 ! tyrosine phosphorylation of STAT protein [Term] id: CCO:P0002068 name: tyrosine phosphorylation of Stat3 protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a Stat3 protein." [GOC:jl, PMID:11426647] xref: GO:0042503 is_a: CCO:P0000777 ! tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0055018 ! ONCM_HUMAN [Term] id: CCO:P0002069 name: tyrosine phosphorylation of Stat4 protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a Stat4 protein." [GOC:jl, PMID:11426647] xref: GO:0042504 is_a: CCO:P0000777 ! tyrosine phosphorylation of STAT protein [Term] id: CCO:P0002070 name: tyrosine phosphorylation of Stat6 protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a Stat6 protein." [GOC:jl, PMID:11426647] xref: GO:0042505 is_a: CCO:P0000777 ! tyrosine phosphorylation of STAT protein [Term] id: CCO:P0002071 name: tyrosine phosphorylation of Stat5 protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a Stat5 protein." [GOC:jl, PMID:11426647] xref: GO:0042506 is_a: CCO:P0000777 ! tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0055018 ! ONCM_HUMAN [Term] id: CCO:P0002072 name: tyrosine phosphorylation of Stat7 protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a Stat7 protein." [GOC:jl, PMID:11426647] xref: GO:0042507 is_a: CCO:P0000777 ! tyrosine phosphorylation of STAT protein [Term] id: CCO:P0002073 name: tyrosine phosphorylation of Stat1 protein namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594] xref: GO:0042508 is_a: CCO:P0000777 ! tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0055018 ! ONCM_HUMAN [Term] id: CCO:P0002074 name: regulation of tyrosine phosphorylation of STAT protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] xref: GO:0042509 is_a: CCO:P0002692 ! regulation of JAK-STAT cascade is_a: CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation relationship: regulates CCO:P0000777 ! tyrosine phosphorylation of STAT protein [Term] id: CCO:P0002075 name: regulation of tyrosine phosphorylation of Stat1 protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594] xref: GO:0042510 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein relationship: regulates CCO:P0002073 ! tyrosine phosphorylation of Stat1 protein [Term] id: CCO:P0002076 name: positive regulation of tyrosine phosphorylation of Stat1 protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594] synonym: "activation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat1 protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat1 protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat1 protein" EXACT [] xref: GO:0042511 is_a: CCO:P0002075 ! regulation of tyrosine phosphorylation of Stat1 protein is_a: CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: positively_regulates CCO:P0002073 ! tyrosine phosphorylation of Stat1 protein [Term] id: CCO:P0002077 name: negative regulation of tyrosine phosphorylation of Stat1 protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein." [GOC:jl, PMID:10918594] synonym: "down regulation of tyrosine phosphorylation of Stat1 protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat1 protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat1 protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of Stat1 protein" NARROW [] xref: GO:0042512 is_a: CCO:P0002075 ! regulation of tyrosine phosphorylation of Stat1 protein is_a: CCO:P0002097 ! negative regulation of tyrosine phosphorylation of STAT protein relationship: negatively_regulates CCO:P0002073 ! tyrosine phosphorylation of Stat1 protein [Term] id: CCO:P0002078 name: regulation of tyrosine phosphorylation of Stat2 protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat2 protein." [GOC:jl, PMID:10918594] xref: GO:0042513 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein relationship: regulates CCO:P0002067 ! tyrosine phosphorylation of Stat2 protein [Term] id: CCO:P0002079 name: negative regulation of tyrosine phosphorylation of Stat2 protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat2 protein." [GOC:jl, PMID:10918594] synonym: "down regulation of tyrosine phosphorylation of Stat2 protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat2 protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat2 protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of Stat2 protein" NARROW [] xref: GO:0042514 is_a: CCO:P0002078 ! regulation of tyrosine phosphorylation of Stat2 protein is_a: CCO:P0002097 ! negative regulation of tyrosine phosphorylation of STAT protein relationship: negatively_regulates CCO:P0002067 ! tyrosine phosphorylation of Stat2 protein [Term] id: CCO:P0002080 name: positive regulation of tyrosine phosphorylation of Stat2 protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat2 protein." [GOC:jl, PMID:10918594] synonym: "activation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat2 protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat2 protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat2 protein" EXACT [] xref: GO:0042515 is_a: CCO:P0002078 ! regulation of tyrosine phosphorylation of Stat2 protein is_a: CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: positively_regulates CCO:P0002067 ! tyrosine phosphorylation of Stat2 protein [Term] id: CCO:P0002081 name: regulation of tyrosine phosphorylation of Stat3 protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat3 protein." [GOC:jl, PMID:11426647] xref: GO:0042516 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0058134 ! I22R2_HUMAN relationship: has_participant CCO:B0058642 ! IL22_HUMAN relationship: regulates CCO:P0002068 ! tyrosine phosphorylation of Stat3 protein [Term] id: CCO:P0002082 name: positive regulation of tyrosine phosphorylation of Stat3 protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat3 protein." [GOC:jl, PMID:11426647] synonym: "activation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat3 protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat3 protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat3 protein" EXACT [] xref: GO:0042517 is_a: CCO:P0002081 ! regulation of tyrosine phosphorylation of Stat3 protein is_a: CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0058987 ! IL20_HUMAN relationship: has_participant CCO:B0059069 ! CLCF1_HUMAN relationship: positively_regulates CCO:P0002068 ! tyrosine phosphorylation of Stat3 protein [Term] id: CCO:P0002083 name: negative regulation of tyrosine phosphorylation of Stat3 protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat3 protein." [GOC:jl, PMID:11426647] synonym: "down regulation of tyrosine phosphorylation of Stat3 protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat3 protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat3 protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of Stat3 protein" NARROW [] xref: GO:0042518 is_a: CCO:P0002081 ! regulation of tyrosine phosphorylation of Stat3 protein is_a: CCO:P0002097 ! negative regulation of tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: negatively_regulates CCO:P0002068 ! tyrosine phosphorylation of Stat3 protein [Term] id: CCO:P0002084 name: regulation of tyrosine phosphorylation of Stat4 protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat4 protein." [GOC:jl, PMID:11426647] xref: GO:0042519 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein relationship: regulates CCO:P0002069 ! tyrosine phosphorylation of Stat4 protein [Term] id: CCO:P0002085 name: positive regulation of tyrosine phosphorylation of Stat4 protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat4 protein." [GOC:jl, PMID:11426647] synonym: "activation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat4 protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat4 protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat4 protein" EXACT [] xref: GO:0042520 is_a: CCO:P0002084 ! regulation of tyrosine phosphorylation of Stat4 protein is_a: CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: positively_regulates CCO:P0002069 ! tyrosine phosphorylation of Stat4 protein [Term] id: CCO:P0002086 name: negative regulation of tyrosine phosphorylation of Stat4 protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat4 protein." [GOC:jl, PMID:11426647] synonym: "down regulation of tyrosine phosphorylation of Stat4 protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat4 protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat4 protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of Stat4 protein" NARROW [] xref: GO:0042521 is_a: CCO:P0002084 ! regulation of tyrosine phosphorylation of Stat4 protein is_a: CCO:P0002097 ! negative regulation of tyrosine phosphorylation of STAT protein relationship: negatively_regulates CCO:P0002069 ! tyrosine phosphorylation of Stat4 protein [Term] id: CCO:P0002087 name: regulation of tyrosine phosphorylation of Stat5 protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat5 protein." [GOC:jl, PMID:11426647] xref: GO:0042522 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein relationship: regulates CCO:P0002071 ! tyrosine phosphorylation of Stat5 protein [Term] id: CCO:P0002088 name: positive regulation of tyrosine phosphorylation of Stat5 protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat5 protein." [GOC:jl, PMID:11426647] synonym: "activation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat5 protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat5 protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat5 protein" EXACT [] xref: GO:0042523 is_a: CCO:P0002087 ! regulation of tyrosine phosphorylation of Stat5 protein is_a: CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0054885 ! CSF2_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: positively_regulates CCO:P0002071 ! tyrosine phosphorylation of Stat5 protein [Term] id: CCO:P0002089 name: negative regulation of tyrosine phosphorylation of Stat5 protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat5 protein." [GOC:jl, PMID:11426647] synonym: "down regulation of tyrosine phosphorylation of Stat5 protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat5 protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat5 protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of Stat5 protein" NARROW [] xref: GO:0042524 is_a: CCO:P0002087 ! regulation of tyrosine phosphorylation of Stat5 protein is_a: CCO:P0002097 ! negative regulation of tyrosine phosphorylation of STAT protein relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: negatively_regulates CCO:P0002071 ! tyrosine phosphorylation of Stat5 protein [Term] id: CCO:P0002090 name: regulation of tyrosine phosphorylation of Stat6 protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat6 protein." [GOC:jl, PMID:11426647] xref: GO:0042525 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein relationship: regulates CCO:P0002070 ! tyrosine phosphorylation of Stat6 protein [Term] id: CCO:P0002091 name: positive regulation of tyrosine phosphorylation of Stat6 protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat6 protein." [GOC:jl, PMID:11426647] synonym: "activation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat6 protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat6 protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat6 protein" EXACT [] xref: GO:0042526 is_a: CCO:P0002090 ! regulation of tyrosine phosphorylation of Stat6 protein is_a: CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: positively_regulates CCO:P0002070 ! tyrosine phosphorylation of Stat6 protein [Term] id: CCO:P0002092 name: negative regulation of tyrosine phosphorylation of Stat6 protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat6 protein." [GOC:jl, PMID:11426647] synonym: "down regulation of tyrosine phosphorylation of Stat6 protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat6 protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat6 protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of Stat6 protein" NARROW [] xref: GO:0042527 is_a: CCO:P0002090 ! regulation of tyrosine phosphorylation of Stat6 protein is_a: CCO:P0002097 ! negative regulation of tyrosine phosphorylation of STAT protein relationship: negatively_regulates CCO:P0002070 ! tyrosine phosphorylation of Stat6 protein [Term] id: CCO:P0002093 name: regulation of tyrosine phosphorylation of Stat7 protein namespace: biological_process def: "Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat7 protein." [GOC:jl, PMID:11426647] xref: GO:0042528 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein relationship: regulates CCO:P0002072 ! tyrosine phosphorylation of Stat7 protein [Term] id: CCO:P0002094 name: positive regulation of tyrosine phosphorylation of Stat7 protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat7 protein." [GOC:jl, PMID:11426647] synonym: "activation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat7 protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat7 protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat7 protein" EXACT [] xref: GO:0042529 is_a: CCO:P0002093 ! regulation of tyrosine phosphorylation of Stat7 protein is_a: CCO:P0002096 ! positive regulation of tyrosine phosphorylation of STAT protein relationship: positively_regulates CCO:P0002072 ! tyrosine phosphorylation of Stat7 protein [Term] id: CCO:P0002095 name: negative regulation of tyrosine phosphorylation of Stat7 protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat7 protein." [GOC:jl, PMID:11426647] synonym: "down regulation of tyrosine phosphorylation of Stat7 protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat7 protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat7 protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of Stat7 protein" NARROW [] xref: GO:0042530 is_a: CCO:P0002093 ! regulation of tyrosine phosphorylation of Stat7 protein is_a: CCO:P0002097 ! negative regulation of tyrosine phosphorylation of STAT protein relationship: negatively_regulates CCO:P0002072 ! tyrosine phosphorylation of Stat7 protein [Term] id: CCO:P0002096 name: positive regulation of tyrosine phosphorylation of STAT protein namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] synonym: "activation of tyrosine phosphorylation of STAT protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of STAT protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of STAT protein" EXACT [] xref: GO:0042531 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein is_a: CCO:P0002694 ! positive regulation of JAK-STAT cascade is_a: CCO:P0002935 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: has_participant CCO:B0005457 ! LYN_HUMAN relationship: has_participant CCO:B0055023 ! HCLS1_HUMAN relationship: has_participant CCO:B0057317 ! IL29_HUMAN relationship: positively_regulates CCO:P0000777 ! tyrosine phosphorylation of STAT protein [Term] id: CCO:P0002097 name: negative regulation of tyrosine phosphorylation of STAT protein namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] synonym: "down regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "inhibition of tyrosine phosphorylation of STAT protein" NARROW [] xref: GO:0042532 is_a: CCO:P0002074 ! regulation of tyrosine phosphorylation of STAT protein is_a: CCO:P0002693 ! negative regulation of JAK-STAT cascade is_a: CCO:P0002936 ! negative regulation of peptidyl-tyrosine phosphorylation relationship: negatively_regulates CCO:P0000777 ! tyrosine phosphorylation of STAT protein [Term] id: CCO:P0002098 name: regulation of tumor necrosis factor biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884] comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). synonym: "regulation of TNF alpha biosynthesis" EXACT [] synonym: "regulation of TNF alpha biosynthetic process" EXACT [] synonym: "regulation of TNF biosynthesis" EXACT [] synonym: "regulation of TNF biosynthetic process" EXACT [] synonym: "regulation of TNF-alpha biosynthesis" EXACT [] synonym: "regulation of TNF-alpha biosynthetic process" EXACT [] synonym: "regulation of tumor necrosis factor anabolism" EXACT [] synonym: "regulation of tumor necrosis factor biosynthesis" EXACT [] synonym: "regulation of tumor necrosis factor formation" EXACT [] synonym: "regulation of tumor necrosis factor synthesis" EXACT [] synonym: "regulation of tumor necrosis factor-alpha biosynthesis" EXACT [] synonym: "regulation of tumor necrosis factor-alpha biosynthetic process" EXACT [] xref: GO:0042534 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002099 name: positive regulation of tumor necrosis factor biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884] comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). synonym: "activation of tumor necrosis factor biosynthetic process" NARROW [] synonym: "positive regulation of TNF alpha biosynthesis" EXACT [] synonym: "positive regulation of TNF alpha biosynthetic process" EXACT [] synonym: "positive regulation of TNF biosynthesis" EXACT [] synonym: "positive regulation of TNF biosynthetic process" EXACT [] synonym: "positive regulation of TNF-alpha biosynthesis" EXACT [] synonym: "positive regulation of TNF-alpha biosynthetic process" EXACT [] synonym: "positive regulation of tumor necrosis factor anabolism" EXACT [] synonym: "positive regulation of tumor necrosis factor biosynthesis" EXACT [] synonym: "positive regulation of tumor necrosis factor formation" EXACT [] synonym: "positive regulation of tumor necrosis factor synthesis" EXACT [] synonym: "positive regulation of tumor necrosis factor-alpha biosynthesis" EXACT [] synonym: "positive regulation of tumor necrosis factor-alpha biosynthetic process" EXACT [] synonym: "stimulation of tumor necrosis factor biosynthetic process" NARROW [] synonym: "up regulation of tumor necrosis factor biosynthetic process" EXACT [] synonym: "up-regulation of tumor necrosis factor biosynthetic process" EXACT [] synonym: "upregulation of tumor necrosis factor biosynthetic process" EXACT [] xref: GO:0042535 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002098 ! regulation of tumor necrosis factor biosynthetic process relationship: has_participant CCO:B0006010 ! TNR8_HUMAN relationship: has_participant CCO:B0022071 ! TLR4_HUMAN relationship: has_participant CCO:B0030164 ! TLR1_HUMAN relationship: has_participant CCO:B0055047 ! LEUK_HUMAN relationship: has_participant CCO:B0055114 ! CAP7_HUMAN relationship: has_participant CCO:B0057234 ! Q86SR2_HUMAN [Term] id: CCO:P0002100 name: negative regulation of tumor necrosis factor biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis." [GOC:jl, PMID:10891884] comment: Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). synonym: "down regulation of tumor necrosis factor biosynthetic process" EXACT [] synonym: "down-regulation of tumor necrosis factor biosynthetic process" EXACT [] synonym: "downregulation of tumor necrosis factor biosynthetic process" EXACT [] synonym: "inhibition of tumor necrosis factor biosynthetic process" NARROW [] synonym: "negative regulation of TNF alpha biosynthesis" EXACT [] synonym: "negative regulation of TNF alpha biosynthetic process" EXACT [] synonym: "negative regulation of TNF biosynthesis" EXACT [] synonym: "negative regulation of TNF biosynthetic process" EXACT [] synonym: "negative regulation of TNF-alpha biosynthesis" EXACT [] synonym: "negative regulation of TNF-alpha biosynthetic process" EXACT [] synonym: "negative regulation of tumor necrosis factor anabolism" EXACT [] synonym: "negative regulation of tumor necrosis factor biosynthesis" EXACT [] synonym: "negative regulation of tumor necrosis factor formation" EXACT [] synonym: "negative regulation of tumor necrosis factor synthesis" EXACT [] synonym: "negative regulation of tumor necrosis factor-alpha biosynthesis" EXACT [] synonym: "negative regulation of tumor necrosis factor-alpha biosynthetic process" EXACT [] xref: GO:0042536 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002098 ! regulation of tumor necrosis factor biosynthetic process relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN [Term] id: CCO:P0002101 name: regulation of photosynthesis, light reaction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis." [GOC:jl] xref: GO:0042548 is_a: CCO:P0000909 ! regulation of photosynthesis is_a: CCO:P0002217 ! regulation of generation of precursor metabolites and energy [Term] id: CCO:P0002102 name: photosystem II stabilization namespace: biological_process def: "The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis." [GOC:go_curators] xref: GO:0042549 is_a: CCO:P0002101 ! regulation of photosynthesis, light reaction [Term] id: CCO:P0002103 name: photosystem I stabilization namespace: biological_process def: "The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis." [GOC:go_curators] xref: GO:0042550 is_a: CCO:P0002101 ! regulation of photosynthesis, light reaction [Term] id: CCO:P0002104 name: activation of JNKKK activity namespace: biological_process def: "The initiation of the activity of the inactive enzyme JUN kinase kinase kinase activity in response to phosphorylation by a member of the MAP kinase kinase kinase kinase (MAPKKKK) family or another upstream kinase." [GOC:bf] synonym: "activation of JUN kinase kinase kinase activity" EXACT [] synonym: "positive regulation of JUNKKK activity" BROAD [] xref: GO:0042655 is_a: CCO:P0000409 ! activation of MAPKKK activity relationship: part_of CCO:P0000772 ! JNK cascade [Term] id: CCO:P0002105 name: regulation of cell fate specification namespace: biological_process def: "Any process that mediates the adoption of a specific fate by a cell." [GOC:go_curators] xref: GO:0042659 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002106 name: positive regulation of cell fate specification namespace: biological_process def: "Any process that activates or enables a cell to adopt a specific fate." [GOC:go_curators] synonym: "activation of cell fate specification" NARROW [] synonym: "stimulation of cell fate specification" NARROW [] synonym: "up regulation of cell fate specification" EXACT [] synonym: "up-regulation of cell fate specification" EXACT [] synonym: "upregulation of cell fate specification" EXACT [] xref: GO:0042660 is_a: CCO:P0002105 ! regulation of cell fate specification is_a: CCO:P0002411 ! positive regulation of cell differentiation relationship: has_participant CCO:B0002083 ! GFI1_HUMAN [Term] id: CCO:P0002107 name: regulation of mesodermal cell fate specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm cell fate specification." [GOC:go_curators] xref: GO:0042661 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0002108 name: negative regulation of mesodermal cell fate specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm cell fate specification." [GOC:go_curators] synonym: "down regulation of mesodermal cell fate specification" EXACT [] synonym: "down-regulation of mesodermal cell fate specification" EXACT [] synonym: "downregulation of mesodermal cell fate specification" EXACT [] synonym: "inhibition of mesodermal cell fate specification" NARROW [] synonym: "suppression of mesodermal cell fate" EXACT [] xref: GO:0042662 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0002107 ! regulation of mesodermal cell fate specification [Term] id: CCO:P0002109 name: regulation of endodermal cell fate specification namespace: biological_process def: "Any process that mediates the specification of a cell into an endoderm cell." [GOC:go_curators] synonym: "regulation of endoderm cell fate specification" EXACT [] xref: GO:0042663 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0002110 name: negative regulation of endodermal cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from specifying into an endoderm cell." [GOC:go_curators] synonym: "down regulation of endodermal cell fate specification" EXACT [] synonym: "down-regulation of endodermal cell fate specification" EXACT [] synonym: "downregulation of endodermal cell fate specification" EXACT [] synonym: "inhibition of endodermal cell fate specification" NARROW [] synonym: "negative regulation of endoderm cell fate specification" EXACT [] synonym: "suppression of endoderm cell fate" EXACT [] synonym: "suppression of endodermal cell fate" EXACT [] xref: GO:0042664 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0002109 ! regulation of endodermal cell fate specification [Term] id: CCO:P0002111 name: regulation of ectodermal cell fate specification namespace: biological_process def: "Any process that mediates the specification of a cell into an ectoderm cell." [GOC:go_curators] synonym: "regulation of ectoderm cell fate specification" EXACT [] xref: GO:0042665 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0002112 name: negative regulation of ectodermal cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell." [GOC:go_curators] synonym: "down regulation of ectodermal cell fate specification" EXACT [] synonym: "down-regulation of ectodermal cell fate specification" EXACT [] synonym: "downregulation of ectodermal cell fate specification" EXACT [] synonym: "inhibition of ectodermal cell fate specification" NARROW [] synonym: "negative regulation of ectoderm cell fate specification" EXACT [] synonym: "suppression of ectoderm cell fate" EXACT [] synonym: "suppression of ectodermal cell fate" EXACT [] xref: GO:0042666 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0002111 ! regulation of ectodermal cell fate specification [Term] id: CCO:P0002113 name: regulation of auditory receptor cell fate specification namespace: biological_process def: "Any process that mediates the specification of a cell into an auditory hair cell." [GOC:go_curators] synonym: "regulation of auditory hair cell fate specification" EXACT [] xref: GO:0042669 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0002114 name: regulation of retinal cone cell fate specification namespace: biological_process def: "Any process that mediates the specification of a cell into a retinal cone cell." [GOC:go_curators] xref: GO:0042673 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0002115 name: regulation of compound eye cone cell fate specification namespace: biological_process def: "Any process that mediates the specification of a cell into a compound eye cone cell." [GOC:mtg_sensu] synonym: "regulation of cone cell fate specification (sensu Endopterygota)" EXACT [] xref: GO:0042681 xref: GO:0042682 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0002116 name: negative regulation of compound eye cone cell fate specification namespace: biological_process def: "Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell." [GOC:mtg_sensu] synonym: "down regulation of cone cell fate specification" EXACT [] synonym: "down regulation of cone cell fate specification (sensu Endopterygota)" EXACT [] synonym: "down-regulation of cone cell fate specification" EXACT [] synonym: "down-regulation of cone cell fate specification (sensu Endopterygota)" EXACT [] synonym: "downregulation of cone cell fate specification" EXACT [] synonym: "downregulation of cone cell fate specification (sensu Endopterygota)" EXACT [] synonym: "inhibition of cone cell fate specification" NARROW [] synonym: "inhibition of cone cell fate specification (sensu Endopterygota)" NARROW [] synonym: "negative regulation of cone cell fate specification (sensu Endopterygota)" EXACT [] synonym: "suppression of cone cell fate (sensu Drosophila)" EXACT [] xref: GO:0010000 xref: GO:0042683 is_a: CCO:P0000888 ! negative regulation of cell fate specification is_a: CCO:P0002115 ! regulation of compound eye cone cell fate specification [Term] id: CCO:P0002117 name: regulation of cardioblast cell fate specification namespace: biological_process def: "Any process that mediates the specification of a cell into a cardioblast." [GOC:go_curators] xref: GO:0042686 is_a: CCO:P0002105 ! regulation of cell fate specification [Term] id: CCO:P0002118 name: regulation of crystal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of crystal cell differentiation." [GOC:go_curators] xref: GO:0042689 is_a: CCO:P0002424 ! regulation of hemocyte differentiation [Term] id: CCO:P0002119 name: negative regulation of crystal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of crystal cell differentiation." [GOC:go_curators] synonym: "down regulation of crystal cell differentiation" EXACT [] synonym: "down-regulation of crystal cell differentiation" EXACT [] synonym: "downregulation of crystal cell differentiation" EXACT [] synonym: "inhibition of crystal cell differentiation" NARROW [] xref: GO:0042690 is_a: CCO:P0002118 ! regulation of crystal cell differentiation is_a: CCO:P0002425 ! negative regulation of hemocyte differentiation [Term] id: CCO:P0002120 name: positive regulation of crystal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of crystal cell differentiation." [GOC:go_curators] synonym: "activation of crystal cell differentiation" NARROW [] synonym: "stimulation of crystal cell differentiation" NARROW [] synonym: "up regulation of crystal cell differentiation" EXACT [] synonym: "up-regulation of crystal cell differentiation" EXACT [] synonym: "upregulation of crystal cell differentiation" EXACT [] xref: GO:0042691 is_a: CCO:P0002118 ! regulation of crystal cell differentiation is_a: CCO:P0002426 ! positive regulation of hemocyte differentiation [Term] id: CCO:P0002121 name: follicle-stimulating hormone signaling pathway namespace: biological_process def: "The series of molecular signals mediated by follicle-stimulating hormone." [GOC:dph] synonym: "follicle stimulating hormone signaling pathway" EXACT [] synonym: "follicle-stimulating hormone signalling pathway" EXACT [] xref: GO:0042699 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0002122 name: dosage compensation complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes." [GOC:jl, PMID:11102361, PMID:12672493] xref: GO:0042714 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000803 ! dosage compensation [Term] id: CCO:P0002123 name: dosage compensation complex assembly during dosage compensation by hypoactivation of X chromosome namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on both X chromosomes in the monogametic sex, ultimately resulting in a two-fold reduction in transcription from these chromosomes." [GOC:jl, PMID:11102361, PMID:12672493] synonym: "dosage compensation complex assembly (sensu Nematoda)" EXACT [] xref: GO:0042715 is_a: CCO:P0002122 ! dosage compensation complex assembly relationship: part_of CCO:P0002062 ! dosage compensation, by hypoactivation of X chromosome [Term] id: CCO:P0002124 name: regulation of sulfur metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of sulfur metabolism" EXACT [] synonym: "regulation of sulphur metabolic process" EXACT [] synonym: "regulation of sulphur metabolism" EXACT [] xref: GO:0042762 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0002125 name: DNA damage response, signal transduction namespace: biological_process def: "A cascade of processes induced by the detection of DNA damage within a cell." [GOC:go_curators] xref: GO:0042770 is_a: CCO:P0000766 ! intracellular signaling cascade relationship: has_participant CCO:B0001459 ! CHK2_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN [Term] id: CCO:P0002126 name: DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis namespace: biological_process def: "A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the initiation of apoptosis (programmed cell death)." [GOC:go_curators] xref: GO:0042771 is_a: CCO:P0000837 ! DNA damage response, signal transduction resulting in induction of apoptosis is_a: CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001570 ! PML_HUMAN relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0005265 ! DYRK2_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0056172 ! IF16_HUMAN relationship: has_participant CCO:B0058693 ! LITFL_HUMAN [Term] id: CCO:P0002127 name: DNA damage response, signal transduction resulting in transcription namespace: biological_process def: "A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription." [GOC:go_curators] xref: GO:0042772 is_a: CCO:P0002125 ! DNA damage response, signal transduction [Term] id: CCO:P0002128 name: glucocorticoid receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor." [GOC:mah] synonym: "glucocorticoid receptor signalling pathway" EXACT [] xref: GO:0042921 is_a: CCO:P0001515 ! corticosteroid receptor signaling pathway relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN relationship: has_participant CCO:B0058337 ! RBM14_HUMAN [Term] id: CCO:P0002129 name: activation of Janus kinase activity namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it." [GOC:jl, PMID:12479803] synonym: "activation of JAK protein" EXACT [GOC:dph, GOC:tb] synonym: "activation of JAK protein by tyrosine phosphorylation" EXACT [] synonym: "positive regulation of JAK protein activity by tyrosine phosphorylation" BROAD [] synonym: "tyrosine phosphorylation of JAK protein" RELATED [] xref: GO:0042976 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0002130 name: activation of JAK2 kinase activity namespace: biological_process def: "The process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it." [GOC:jl, PMID:12479803] synonym: "activation of JAK2 protein" EXACT [GOC:dph, GOC:tb] synonym: "tyrosine phosphorylation of JAK2 protein" RELATED [] xref: GO:0042977 is_a: CCO:P0002129 ! activation of Janus kinase activity relationship: has_participant CCO:B0055053 ! PRLR_HUMAN [Term] id: CCO:P0002131 name: regulation of apoptosis namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptosis." [GOC:jl] synonym: "apoptosis regulator activity" RELATED [] xref: GO:0042981 is_a: CCO:P0002149 ! regulation of programmed cell death relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0001520 ! ERF3A_HUMAN relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0001563 ! CALR_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0001758 ! ULA1_HUMAN relationship: has_participant CCO:B0001993 ! DLG5_HUMAN relationship: has_participant CCO:B0002010 ! MADD_HUMAN relationship: has_participant CCO:B0002074 ! MNT_HUMAN relationship: has_participant CCO:B0002098 ! HTAI2_HUMAN relationship: has_participant CCO:B0002132 ! Q9H315_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005358 ! WRN_HUMAN relationship: has_participant CCO:B0005421 ! BIK_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0005479 ! TNR6_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005642 ! ACTN2_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005730 ! CH60_HUMAN relationship: has_participant CCO:B0005818 ! DNJA3_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005901 ! BCLX_HUMAN relationship: has_participant CCO:B0005903 ! CASP9_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0005992 ! TRAF1_HUMAN relationship: has_participant CCO:B0006182 ! CRADD_HUMAN relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0006345 ! CATB_HUMAN relationship: has_participant CCO:B0016462 ! Q9NYG7_HUMAN relationship: has_participant CCO:B0020080 ! ACTN3_HUMAN relationship: has_participant CCO:B0020368 ! ACV1C_HUMAN relationship: has_participant CCO:B0021184 ! TERA_HUMAN relationship: has_participant CCO:B0022753 ! MST4_HUMAN relationship: has_participant CCO:B0026578 ! A8MU92_HUMAN relationship: has_participant CCO:B0026744 ! B2L13_HUMAN relationship: has_participant CCO:B0028579 ! Q9H1R6_HUMAN relationship: has_participant CCO:B0028580 ! Q5QP56_HUMAN relationship: has_participant CCO:B0028581 ! Q5QP59_HUMAN relationship: has_participant CCO:B0028582 ! Q5TE64_HUMAN relationship: has_participant CCO:B0028585 ! BCLW_HUMAN relationship: has_participant CCO:B0029119 ! Q9UL32_HUMAN relationship: has_participant CCO:B0029122 ! BOK_HUMAN relationship: has_participant CCO:B0036188 ! TCTP_HUMAN relationship: has_participant CCO:B0040467 ! CASP1_HUMAN relationship: has_participant CCO:B0040469 ! Q5FBZ0_HUMAN relationship: has_participant CCO:B0040471 ! CASP4_HUMAN relationship: has_participant CCO:B0040472 ! INCA_HUMAN relationship: has_participant CCO:B0040474 ! ICBR_HUMAN relationship: has_participant CCO:B0040476 ! O95601_HUMAN relationship: has_participant CCO:B0040477 ! Q0QVY8_HUMAN relationship: has_participant CCO:B0040479 ! Q0QVY7_HUMAN relationship: has_participant CCO:B0040484 ! CASP5_HUMAN relationship: has_participant CCO:B0040485 ! CASPC_HUMAN relationship: has_participant CCO:B0040488 ! Q96RJ9_HUMAN relationship: has_participant CCO:B0040491 ! COP_HUMAN relationship: has_participant CCO:B0041735 ! RTN4_HUMAN relationship: has_participant CCO:B0042116 ! GDF5_HUMAN relationship: has_participant CCO:B0043604 ! DEDD_HUMAN relationship: has_participant CCO:B0043605 ! DEDD2_HUMAN relationship: has_participant CCO:B0043606 ! B1AQP5_HUMAN relationship: has_participant CCO:B0053847 ! A6NHG8_HUMAN relationship: has_participant CCO:B0054233 ! B1AKZ3_HUMAN relationship: has_participant CCO:B0054234 ! B1AKZ5_HUMAN relationship: has_participant CCO:B0054258 ! B1AMX9_HUMAN relationship: has_participant CCO:B0054298 ! HRK_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN relationship: has_participant CCO:B0054371 ! APAF_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0054591 ! NOL3_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054916 ! CD3E_HUMAN relationship: has_participant CCO:B0054942 ! LEG1_HUMAN relationship: has_participant CCO:B0054949 ! CD3G_HUMAN relationship: has_participant CCO:B0055249 ! PRDX2_HUMAN relationship: has_participant CCO:B0055352 ! CASP2_HUMAN relationship: has_participant CCO:B0055403 ! SOX9_HUMAN relationship: has_participant CCO:B0055615 ! BTG1_HUMAN relationship: has_participant CCO:B0055785 ! MCL1_HUMAN relationship: has_participant CCO:B0055866 ! BAK2_HUMAN relationship: has_participant CCO:B0055874 ! TRAF3_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0055917 ! BIRC3_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0056045 ! PEA15_HUMAN relationship: has_participant CCO:B0056148 ! B2LA1_HUMAN relationship: has_participant CCO:B0056236 ! Q2YD93_HUMAN relationship: has_participant CCO:B0056267 ! Q3SX80_HUMAN relationship: has_participant CCO:B0056313 ! Q4G0N6_HUMAN relationship: has_participant CCO:B0056387 ! Q59F61_HUMAN relationship: has_participant CCO:B0056405 ! Q59GG2_HUMAN relationship: has_participant CCO:B0056441 ! Q5HCI0_HUMAN relationship: has_participant CCO:B0056471 ! Q5JRU8_HUMAN relationship: has_participant CCO:B0056711 ! Q68HC0_HUMAN relationship: has_participant CCO:B0056835 ! Q6KF62_HUMAN relationship: has_participant CCO:B0056836 ! Q6KF63_HUMAN relationship: has_participant CCO:B0056926 ! TRAF7_HUMAN relationship: has_participant CCO:B0056973 ! Q6XZE5_HUMAN relationship: has_participant CCO:B0057272 ! Q86W13_HUMAN relationship: has_participant CCO:B0057326 ! Q8IUP5_HUMAN relationship: has_participant CCO:B0057382 ! Q8IY43_HUMAN relationship: has_participant CCO:B0057601 ! Q8NFF3_HUMAN relationship: has_participant CCO:B0058106 ! CASPA_HUMAN relationship: has_participant CCO:B0058121 ! TNR25_HUMAN relationship: has_participant CCO:B0058423 ! P2RX4_HUMAN relationship: has_participant CCO:B0058424 ! P2RX7_HUMAN relationship: has_participant CCO:B0058525 ! TRAF4_HUMAN relationship: has_participant CCO:B0058537 ! CAR10_HUMAN relationship: has_participant CCO:B0058544 ! CARD6_HUMAN relationship: has_participant CCO:B0058558 ! CAR14_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN relationship: has_participant CCO:B0058571 ! PECR_HUMAN relationship: has_participant CCO:B0058587 ! IFIH1_HUMAN relationship: has_participant CCO:B0058603 ! Q9BZL0_HUMAN relationship: has_participant CCO:B0058605 ! B2L14_HUMAN relationship: has_participant CCO:B0058613 ! NALP1_HUMAN relationship: has_participant CCO:B0058679 ! CARD9_HUMAN relationship: has_participant CCO:B0058795 ! NOD2_HUMAN relationship: has_participant CCO:B0058856 ! NLRC4_HUMAN relationship: has_participant CCO:B0058936 ! IFT57_HUMAN relationship: has_participant CCO:B0059106 ! MALT1_HUMAN relationship: has_participant CCO:B0059188 ! FEM1B_HUMAN relationship: has_participant CCO:B0059290 ! NOD1_HUMAN relationship: has_participant CCO:B0059303 ! CARD8_HUMAN relationship: has_participant CCO:B0059364 ! Q9Y4I4_HUMAN [Term] id: CCO:P0002132 name: regulation of amyloid precursor protein biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of beta-amyloid." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of amyloid precursor protein anabolism" EXACT [] synonym: "regulation of amyloid precursor protein biosynthesis" EXACT [] synonym: "regulation of amyloid precursor protein formation" EXACT [] synonym: "regulation of amyloid precursor protein synthesis" EXACT [] synonym: "regulation of APP biosynthesis" EXACT [] synonym: "regulation of APP biosynthetic process" EXACT [] xref: GO:0042984 is_a: CCO:P0000982 ! regulation of glycoprotein biosynthetic process relationship: has_participant CCO:B0058325 ! NECA3_HUMAN [Term] id: CCO:P0002133 name: negative regulation of amyloid precursor protein biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of beta-amyloid." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of amyloid precursor protein biosynthetic process" EXACT [] synonym: "down-regulation of amyloid precursor protein biosynthetic process" EXACT [] synonym: "downregulation of amyloid precursor protein biosynthetic process" EXACT [] synonym: "inhibition of amyloid precursor protein biosynthetic process" NARROW [] synonym: "negative regulation of amyloid precursor protein anabolism" EXACT [] synonym: "negative regulation of amyloid precursor protein biosynthesis" EXACT [] synonym: "negative regulation of amyloid precursor protein formation" EXACT [] synonym: "negative regulation of amyloid precursor protein synthesis" EXACT [] synonym: "negative regulation of APP biosynthesis" EXACT [] synonym: "negative regulation of APP biosynthetic process" EXACT [] xref: GO:0042985 is_a: CCO:P0000984 ! negative regulation of glycoprotein biosynthetic process is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process is_a: CCO:P0002132 ! regulation of amyloid precursor protein biosynthetic process relationship: has_participant CCO:B0059002 ! Q9NZL1_HUMAN relationship: has_participant CCO:B0059003 ! Q9NZL2_HUMAN relationship: has_participant CCO:B0059394 ! BACE2_HUMAN [Term] id: CCO:P0002134 name: positive regulation of amyloid precursor protein biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of beta-amyloid." [GOC:go_curators] subset: gosubset_prok synonym: "activation of amyloid precursor protein biosynthetic process" NARROW [] synonym: "positive regulation of amyloid precursor protein anabolism" EXACT [] synonym: "positive regulation of amyloid precursor protein biosynthesis" EXACT [] synonym: "positive regulation of amyloid precursor protein formation" EXACT [] synonym: "positive regulation of amyloid precursor protein synthesis" EXACT [] synonym: "positive regulation of APP biosynthesis" EXACT [] synonym: "positive regulation of APP biosynthetic process" EXACT [] synonym: "stimulation of amyloid precursor protein biosynthetic process" NARROW [] synonym: "up regulation of amyloid precursor protein biosynthetic process" EXACT [] synonym: "up-regulation of amyloid precursor protein biosynthetic process" EXACT [] synonym: "upregulation of amyloid precursor protein biosynthetic process" EXACT [] xref: GO:0042986 is_a: CCO:P0000983 ! positive regulation of glycoprotein biosynthetic process is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process is_a: CCO:P0002132 ! regulation of amyloid precursor protein biosynthetic process [Term] id: CCO:P0002135 name: sequestering of actin monomers namespace: biological_process def: "The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers." [GOC:go_curators] synonym: "actin monomer retention" EXACT [] synonym: "actin monomer sequestering" EXACT [] synonym: "actin monomer sequestering activity" RELATED [] synonym: "actin monomer sequestration" EXACT [] synonym: "actin monomer storage" EXACT [] synonym: "retention of actin monomers" EXACT [] synonym: "sequestration of actin monomers" EXACT [] synonym: "storage of actin monomers" EXACT [] xref: GO:0042989 is_a: CCO:P0001330 ! negative regulation of actin filament polymerization relationship: has_participant CCO:B0006115 ! TYB4_HUMAN relationship: has_participant CCO:B0049166 ! Q5T4B6_HUMAN relationship: has_participant CCO:B0049167 ! TMSL2_HUMAN relationship: has_participant CCO:B0049174 ! TMSL1_HUMAN relationship: has_participant CCO:B0049175 ! TMSL3_HUMAN relationship: has_participant CCO:B0049176 ! TYB4Y_HUMAN relationship: has_participant CCO:B0049178 ! TYB10_HUMAN relationship: has_participant CCO:B0049179 ! TMSL6_HUMAN relationship: has_participant CCO:B0058409 ! TYBN_HUMAN [Term] id: CCO:P0002136 name: calcium-dependent phospholipase A2 activation namespace: biological_process def: "A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal." [GOC:jl] xref: GO:0043006 is_a: CCO:P0001145 ! calcium-mediated signaling relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0058632 ! NMUR2_HUMAN [Term] id: CCO:P0002137 name: regulation of fusion of sperm to egg plasma membrane namespace: biological_process def: "Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane." [GOC:jl, http://arbl.cvmbs.colostate.edu/hbooks/pathphys/reprod/fert/fert.html] synonym: "regulation of sperm-oocyte fusion" NARROW [] xref: GO:0043012 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0058335 ! NOX5_HUMAN [Term] id: CCO:P0002138 name: negative regulation of fusion of sperm to egg plasma membrane namespace: biological_process def: "Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane." [GOC:jl, http://arbl.cvmbs.colostate.edu/hbooks/pathphys/reprod/fert/fert.html] synonym: "down regulation of fusion of sperm to egg plasma membrane" EXACT [] synonym: "down-regulation of fusion of sperm to egg plasma membrane" EXACT [] synonym: "downregulation of fusion of sperm to egg plasma membrane" EXACT [] synonym: "inhibition of fusion of sperm to egg plasma membrane" NARROW [] synonym: "inhibition of sperm-oocyte fusion" NARROW [] synonym: "negative regulation of sperm-oocyte fusion" NARROW [] xref: GO:0043013 is_a: CCO:P0002137 ! regulation of fusion of sperm to egg plasma membrane is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis [Term] id: CCO:P0002139 name: regulation of lymphotoxin A biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A." [GOC:jl] synonym: "regulation of LTA biosynthesis" EXACT [] synonym: "regulation of LTA biosynthetic process" EXACT [] synonym: "regulation of lymphotoxin A anabolism" EXACT [] synonym: "regulation of lymphotoxin A biosynthesis" EXACT [] synonym: "regulation of lymphotoxin A formation" EXACT [] synonym: "regulation of lymphotoxin A synthesis" EXACT [] synonym: "regulation of lymphotoxin-alpha biosynthesis" EXACT [] synonym: "regulation of lymphotoxin-alpha biosynthetic process" EXACT [] synonym: "regulation of TNF-B biosynthesis" EXACT [] synonym: "regulation of TNF-B biosynthetic process" EXACT [] synonym: "regulation of TNF-beta biosynthesis" EXACT [] synonym: "regulation of TNF-beta biosynthetic process" EXACT [] synonym: "regulation of tumor necrosis factor-beta biosynthesis" EXACT [] synonym: "regulation of tumor necrosis factor-beta biosynthetic process" EXACT [] xref: GO:0043016 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002140 name: positive regulation of lymphotoxin A biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A." [GOC:jl] synonym: "activation of lymphotoxin A biosynthetic process" NARROW [] synonym: "positive regulation of LTA biosynthesis" EXACT [] synonym: "positive regulation of LTA biosynthetic process" EXACT [] synonym: "positive regulation of lymphotoxin A anabolism" EXACT [] synonym: "positive regulation of lymphotoxin A biosynthesis" EXACT [] synonym: "positive regulation of lymphotoxin A formation" EXACT [] synonym: "positive regulation of lymphotoxin A synthesis" EXACT [] synonym: "positive regulation of lymphotoxin-alpha biosynthesis" EXACT [] synonym: "positive regulation of lymphotoxin-alpha biosynthetic process" EXACT [] synonym: "positive regulation of TNF-B biosynthesis" EXACT [] synonym: "positive regulation of TNF-B biosynthetic process" EXACT [] synonym: "positive regulation of TNF-beta biosynthesis" EXACT [] synonym: "positive regulation of TNF-beta biosynthetic process" EXACT [] synonym: "positive regulation of tumor necrosis factor-beta biosynthesis" EXACT [] synonym: "positive regulation of tumor necrosis factor-beta biosynthetic process" EXACT [] synonym: "stimulation of lymphotoxin A biosynthetic process" NARROW [] synonym: "up regulation of lymphotoxin A biosynthetic process" EXACT [] synonym: "up-regulation of lymphotoxin A biosynthetic process" EXACT [] synonym: "upregulation of lymphotoxin A biosynthetic process" EXACT [] xref: GO:0043017 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002139 ! regulation of lymphotoxin A biosynthetic process relationship: has_participant CCO:B0055346 ! CD86_HUMAN [Term] id: CCO:P0002141 name: negative regulation of lymphotoxin A biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A." [GOC:jl] synonym: "down regulation of lymphotoxin A biosynthetic process" EXACT [] synonym: "down-regulation of lymphotoxin A biosynthetic process" EXACT [] synonym: "downregulation of lymphotoxin A biosynthetic process" EXACT [] synonym: "inhibition of lymphotoxin A biosynthetic process" NARROW [] synonym: "negative regulation of LTA biosynthesis" EXACT [] synonym: "negative regulation of LTA biosynthetic process" EXACT [] synonym: "negative regulation of lymphotoxin A anabolism" EXACT [] synonym: "negative regulation of lymphotoxin A biosynthesis" EXACT [] synonym: "negative regulation of lymphotoxin A formation" EXACT [] synonym: "negative regulation of lymphotoxin A synthesis" EXACT [] synonym: "negative regulation of lymphotoxin-alpha biosynthesis" EXACT [] synonym: "negative regulation of lymphotoxin-alpha biosynthetic process" EXACT [] synonym: "negative regulation of TNF-B biosynthesis" EXACT [] synonym: "negative regulation of TNF-B biosynthetic process" EXACT [] synonym: "negative regulation of TNF-beta biosynthesis" EXACT [] synonym: "negative regulation of TNF-beta biosynthetic process" EXACT [] synonym: "negative regulation of tumor necrosis factor-beta biosynthesis" EXACT [] synonym: "negative regulation of tumor necrosis factor-beta biosynthetic process" EXACT [] xref: GO:0043018 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002139 ! regulation of lymphotoxin A biosynthetic process [Term] id: CCO:P0002142 name: regulation of macrophage activation namespace: biological_process def: "Any process that modulates the frequency or rate of macrophage activation." [GOC:jl] xref: GO:0043030 is_a: CCO:P0000562 ! regulation of leukocyte activation relationship: has_participant CCO:B0049558 ! HG2A_HUMAN relationship: has_participant CCO:B0055021 ! MIF_HUMAN [Term] id: CCO:P0002143 name: negative regulation of macrophage activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage activation." [GOC:jl] synonym: "down regulation of macrophage activation" EXACT [] synonym: "down-regulation of macrophage activation" EXACT [] synonym: "downregulation of macrophage activation" EXACT [] synonym: "inhibition of macrophage activation" NARROW [] xref: GO:0043031 is_a: CCO:P0000563 ! negative regulation of leukocyte activation is_a: CCO:P0002142 ! regulation of macrophage activation relationship: has_participant CCO:B0048954 ! IL31R_HUMAN [Term] id: CCO:P0002144 name: positive regulation of macrophage activation namespace: biological_process def: "Any process that stimulates, induces or increases the rate of macrophage activation." [GOC:jl] synonym: "activation of macrophage activation" NARROW [] synonym: "stimulation of macrophage activation" NARROW [] synonym: "up regulation of macrophage activation" EXACT [] synonym: "up-regulation of macrophage activation" EXACT [] synonym: "upregulation of macrophage activation" EXACT [] xref: GO:0043032 is_a: CCO:P0000564 ! positive regulation of leukocyte activation is_a: CCO:P0002142 ! regulation of macrophage activation relationship: has_participant CCO:B0057369 ! SACA3_HUMAN [Term] id: CCO:P0002145 name: DNA methylation during embryonic development namespace: biological_process def: "The covalent transfer of a methyl group to C-5 of cytosine during embryogenesis, when DNA methylation patterns are established." [GOC:go_curators, PMID:12138111] synonym: "de novo DNA methylation" NARROW [] xref: GO:0043045 is_a: CCO:P0000646 ! DNA methylation relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:P0002146 name: DNA methylation during gametogenesis namespace: biological_process def: "The covalent transfer of a methyl group to C-5 of cytosine during gamete generation, when DNA methylation patterns are established." [GOC:go_curators, PMID:12138111] synonym: "de novo DNA methylation" NARROW [] xref: GO:0043046 is_a: CCO:P0000646 ! DNA methylation relationship: has_participant CCO:B0005947 ! PICK1_HUMAN [Term] id: CCO:P0002147 name: positive regulation of apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptosis." [GOC:jl] synonym: "activation of apoptosis" NARROW [] synonym: "stimulation of apoptosis" NARROW [] synonym: "up regulation of apoptosis" EXACT [] synonym: "up-regulation of apoptosis" EXACT [] synonym: "upregulation of apoptosis" EXACT [] xref: GO:0043065 is_a: CCO:P0002131 ! regulation of apoptosis is_a: CCO:P0002150 ! positive regulation of programmed cell death relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001507 ! TGFB3_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0001717 ! ID3_HUMAN relationship: has_participant CCO:B0002077 ! RAD9A_HUMAN relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0002178 ! MLTK_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005422 ! BID_HUMAN relationship: has_participant CCO:B0005678 ! BNIP3_HUMAN relationship: has_participant CCO:B0005702 ! STK4_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0005848 ! BBC3_HUMAN relationship: has_participant CCO:B0006010 ! TNR8_HUMAN relationship: has_participant CCO:B0016855 ! Q6TE15_HUMAN relationship: has_participant CCO:B0016857 ! Q0MSE7_HUMAN relationship: has_participant CCO:B0016858 ! Q6JTU6_HUMAN relationship: has_participant CCO:B0016862 ! Q6V402_HUMAN relationship: has_participant CCO:B0016863 ! Q8WYM0_HUMAN relationship: has_participant CCO:B0016865 ! Q6TE14_HUMAN relationship: has_participant CCO:B0019657 ! ATL4_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0033014 ! SODC_HUMAN relationship: has_participant CCO:B0034126 ! RARG_HUMAN relationship: has_participant CCO:B0040022 ! JMY_HUMAN relationship: has_participant CCO:B0042031 ! PDIA3_HUMAN relationship: has_participant CCO:B0048650 ! PO4F1_HUMAN relationship: has_participant CCO:B0051620 ! ADSV_HUMAN relationship: has_participant CCO:B0054161 ! B0AZS9_HUMAN relationship: has_participant CCO:B0054423 ! SIVA_HUMAN relationship: has_participant CCO:B0054472 ! MCA3_HUMAN relationship: has_participant CCO:B0054832 ! KNG1_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0055029 ! MMP9_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN relationship: has_participant CCO:B0055148 ! GALA_HUMAN relationship: has_participant CCO:B0055392 ! AL1A3_HUMAN relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055840 ! KCMA1_HUMAN relationship: has_participant CCO:B0055885 ! STK3_HUMAN relationship: has_participant CCO:B0056497 ! Q5JW63_HUMAN relationship: has_participant CCO:B0057033 ! Q6ZQV2_HUMAN relationship: has_participant CCO:B0057354 ! Q8IW90_HUMAN relationship: has_participant CCO:B0058046 ! CSRN3_HUMAN relationship: has_participant CCO:B0058234 ! PAWR_HUMAN relationship: has_participant CCO:B0058704 ! Q9H3K3_HUMAN relationship: has_participant CCO:B0058800 ! CAN10_HUMAN relationship: has_participant CCO:B0058856 ! NLRC4_HUMAN relationship: has_participant CCO:B0058962 ! BCLF1_HUMAN relationship: has_participant CCO:B0059001 ! MTCH1_HUMAN relationship: has_participant CCO:B0059140 ! IP6K2_HUMAN relationship: has_participant CCO:B0059141 ! DDX20_HUMAN relationship: has_participant CCO:B0059254 ! FAF1_HUMAN [Term] id: CCO:P0002148 name: negative regulation of apoptosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis." [GOC:jl] synonym: "down regulation of apoptosis" EXACT [] synonym: "down-regulation of apoptosis" EXACT [] synonym: "downregulation of apoptosis" EXACT [] synonym: "inhibition of apoptosis" NARROW [] xref: GO:0043066 is_a: CCO:P0002131 ! regulation of apoptosis is_a: CCO:P0002151 ! negative regulation of programmed cell death relationship: has_participant CCO:B0001489 ! K1C18_HUMAN relationship: has_participant CCO:B0001500 ! FGF4_HUMAN relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: has_participant CCO:B0001995 ! RBCC1_HUMAN relationship: has_participant CCO:B0002086 ! BARD1_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0005326 ! PK3CG_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005638 ! MK08_HUMAN relationship: has_participant CCO:B0005824 ! CTNA1_HUMAN relationship: has_participant CCO:B0005874 ! NUAK2_HUMAN relationship: has_participant CCO:B0006036 ! ERCC5_HUMAN relationship: has_participant CCO:B0006039 ! SMO_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0019335 ! CATA_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0022781 ! PIM1_HUMAN relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0032819 ! ASNS_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0033778 ! SODM_HUMAN relationship: has_participant CCO:B0049558 ! HG2A_HUMAN relationship: has_participant CCO:B0049794 ! PPT1_HUMAN relationship: has_participant CCO:B0054043 ! A8MUR1_HUMAN relationship: has_participant CCO:B0054307 ! DFFA_HUMAN relationship: has_participant CCO:B0054566 ! CIDEA_HUMAN relationship: has_participant CCO:B0054622 ! PROP1_HUMAN relationship: has_participant CCO:B0054656 ! GCM2_HUMAN relationship: has_participant CCO:B0054871 ! APOH_HUMAN relationship: has_participant CCO:B0054874 ! ALBU_HUMAN relationship: has_participant CCO:B0054884 ! PROC_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0055014 ! SCG2_HUMAN relationship: has_participant CCO:B0055021 ! MIF_HUMAN relationship: has_participant CCO:B0055351 ! CASP3_HUMAN relationship: has_participant CCO:B0055405 ! GSH0_HUMAN relationship: has_participant CCO:B0055526 ! BI1_HUMAN relationship: has_participant CCO:B0055642 ! NKX32_HUMAN relationship: has_participant CCO:B0055649 ! BTG2_HUMAN relationship: has_participant CCO:B0055893 ! CLN3_HUMAN relationship: has_participant CCO:B0055929 ! NDF1_HUMAN relationship: has_participant CCO:B0056004 ! IHH_HUMAN relationship: has_participant CCO:B0056757 ! Q6IAN2_HUMAN relationship: has_participant CCO:B0058421 ! SORT_HUMAN relationship: has_participant CCO:B0058572 ! ANGL4_HUMAN relationship: has_participant CCO:B0058933 ! FAIM1_HUMAN relationship: has_participant CCO:B0059069 ! CLCF1_HUMAN relationship: has_participant CCO:B0059091 ! CLN8_HUMAN [Term] id: CCO:P0002149 name: regulation of programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] xref: GO:0043067 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0002150 name: positive regulation of programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "activation of programmed cell death" NARROW [] synonym: "stimulation of programmed cell death" NARROW [] synonym: "up regulation of programmed cell death" EXACT [] synonym: "up-regulation of programmed cell death" EXACT [] synonym: "upregulation of programmed cell death" EXACT [] xref: GO:0043068 is_a: CCO:P0002149 ! regulation of programmed cell death is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0005344 ! MARK4_HUMAN relationship: has_participant CCO:B0034126 ! RARG_HUMAN relationship: has_participant CCO:B0056531 ! LRRK2_HUMAN [Term] id: CCO:P0002151 name: negative regulation of programmed cell death namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "down regulation of programmed cell death" EXACT [] synonym: "down-regulation of programmed cell death" EXACT [] synonym: "downregulation of programmed cell death" EXACT [] synonym: "inhibition of programmed cell death" NARROW [] xref: GO:0043069 is_a: CCO:P0002149 ! regulation of programmed cell death is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0041253 ! PRS8_HUMAN relationship: has_participant CCO:B0054687 ! WFS1_HUMAN relationship: has_participant CCO:B0057228 ! AMGO2_HUMAN [Term] id: CCO:P0002152 name: regulation of non-apoptotic programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of non-apoptotic programmed cell death, cell death resulting from activation of endogenous cellular processes, by a mechanism other than apoptosis." [GOC:go_curators] synonym: "regulation of nonapoptotic programmed cell death" EXACT [] xref: GO:0043070 is_a: CCO:P0002149 ! regulation of programmed cell death [Term] id: CCO:P0002153 name: positive regulation of non-apoptotic programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of non-apoptotic programmed cell death, cell death resulting from activation of endogenous cellular processes, by a mechanism other than apoptosis." [GOC:go_curators] synonym: "activation of non-apoptotic programmed cell death" NARROW [] synonym: "positive regulation of nonapoptotic programmed cell death" EXACT [] synonym: "stimulation of non-apoptotic programmed cell death" NARROW [] synonym: "up regulation of non-apoptotic programmed cell death" EXACT [] synonym: "up-regulation of non-apoptotic programmed cell death" EXACT [] synonym: "upregulation of non-apoptotic programmed cell death" EXACT [] xref: GO:0043071 is_a: CCO:P0002150 ! positive regulation of programmed cell death is_a: CCO:P0002152 ! regulation of non-apoptotic programmed cell death relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN [Term] id: CCO:P0002154 name: negative regulation of non-apoptotic programmed cell death namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of non-apoptotic programmed cell death, cell death resulting from activation of endogenous cellular processes, by a mechanism other than apoptosis." [GOC:go_curators] synonym: "down regulation of non-apoptotic programmed cell death" EXACT [] synonym: "down-regulation of non-apoptotic programmed cell death" EXACT [] synonym: "downregulation of non-apoptotic programmed cell death" EXACT [] synonym: "inhibition of non-apoptotic programmed cell death" NARROW [] synonym: "negative regulation of nonapoptotic programmed cell death" EXACT [] xref: GO:0043072 is_a: CCO:P0002151 ! negative regulation of programmed cell death is_a: CCO:P0002152 ! regulation of non-apoptotic programmed cell death relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0054874 ! ALBU_HUMAN [Term] id: CCO:P0002155 name: initiation of acetate catabolic process namespace: biological_process def: "The activation of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:jl] subset: gosubset_prok synonym: "initiation of acetate breakdown" EXACT [] synonym: "initiation of acetate catabolism" EXACT [] synonym: "initiation of acetate degradation" EXACT [] xref: GO:0043077 is_a: CCO:P0002539 ! positive regulation of acetate catabolic process [Term] id: CCO:P0002156 name: regulation of Cdc42 GTPase activity namespace: biological_process def: "Any process that modulates the activity of the GTPase Cdc42." [GOC:jl] xref: GO:0043088 is_a: CCO:P0001590 ! regulation of Rho GTPase activity relationship: has_participant CCO:B0055676 ! FGD1_HUMAN relationship: has_participant CCO:B0056480 ! FGD3_HUMAN relationship: has_participant CCO:B0057029 ! FGD5_HUMAN relationship: has_participant CCO:B0057083 ! FGD6_HUMAN relationship: has_participant CCO:B0057198 ! FGD2_HUMAN relationship: has_participant CCO:B0058282 ! FGD4_HUMAN relationship: part_of CCO:P0001635 ! regulation of Cdc42 protein signal transduction [Term] id: CCO:P0002157 name: positive regulation of Cdc42 GTPase activity namespace: biological_process def: "Any process that activates or increases the activity of the GTPase Cdc42." [GOC:jl] synonym: "stimulation of Cdc42 GTPase activity" NARROW [] synonym: "up regulation of Cdc42 GTPase activity" EXACT [] synonym: "up-regulation of Cdc42 GTPase activity" EXACT [] synonym: "upregulation of Cdc42 GTPase activity" EXACT [] xref: GO:0043089 is_a: CCO:P0001592 ! positive regulation of Rho GTPase activity is_a: CCO:P0002156 ! regulation of Cdc42 GTPase activity relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0041368 ! RHG27_HUMAN relationship: has_participant CCO:B0056057 ! RBP1_HUMAN [Term] id: CCO:P0002158 name: binary fission namespace: biological_process def: "A process in which two similarly sized and shaped cells are formed by the division of one cell, the process by which most bacteria reproduce." [ISBN:0815108893] subset: gosubset_prok xref: GO:0043093 is_a: CCO:P0001636 ! reproduction of a single-celled organism [Term] id: CCO:P0002159 name: replication fork arrest namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork." [GOC:jl, PMID:14645529] subset: gosubset_prok synonym: "replication fork blocking" EXACT [] synonym: "replication fork stalling" EXACT [] xref: GO:0043111 is_a: CCO:P0000813 ! negative regulation of DNA replication [Term] id: CCO:P0002160 name: receptor clustering namespace: biological_process def: "Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response." [GOC:bf] xref: GO:0043113 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0005947 ! PICK1_HUMAN relationship: has_participant CCO:B0005949 ! AGRIN_HUMAN relationship: part_of CCO:P0000714 ! signal complex assembly [Term] id: CCO:P0002161 name: regulation of I-kappaB kinase/NF-kappaB cascade namespace: biological_process def: "Any process that modulates an I-kappaB kinase/NF-kappaB induced cascade." [GOC:jl, PMID:12773372] xref: GO:0043122 is_a: CCO:P0001017 ! regulation of protein kinase cascade relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN relationship: has_participant CCO:B0055919 ! Q13502_HUMAN relationship: has_participant CCO:B0058501 ! Q9BRY4_HUMAN relationship: regulates CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:P0002162 name: positive regulation of I-kappaB kinase/NF-kappaB cascade namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade." [GOC:jl] synonym: "activation of I-kappaB kinase/NF-kappaB cascade" NARROW [] synonym: "stimulation of I-kappaB kinase/NF-kappaB cascade" NARROW [] synonym: "up regulation of I-kappaB kinase/NF-kappaB cascade" EXACT [] synonym: "up-regulation of I-kappaB kinase/NF-kappaB cascade" EXACT [] synonym: "upregulation of I-kappaB kinase/NF-kappaB cascade" EXACT [] xref: GO:0043123 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002161 ! regulation of I-kappaB kinase/NF-kappaB cascade relationship: has_participant CCO:B0001416 ! TRI13_HUMAN relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0001662 ! PPP5_HUMAN relationship: has_participant CCO:B0001752 ! UB2V1_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN relationship: has_participant CCO:B0002179 ! PLK2_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005523 ! IKKE_HUMAN relationship: has_participant CCO:B0005526 ! M3K3_HUMAN relationship: has_participant CCO:B0005532 ! TAB2_HUMAN relationship: has_participant CCO:B0005533 ! TBK1_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005649 ! PPM1A_HUMAN relationship: has_participant CCO:B0005655 ! FKB1A_HUMAN relationship: has_participant CCO:B0005671 ! BIRC2_HUMAN relationship: has_participant CCO:B0005672 ! TRADD_HUMAN relationship: has_participant CCO:B0005673 ! RIPK1_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN relationship: has_participant CCO:B0020321 ! MIER1_HUMAN relationship: has_participant CCO:B0020591 ! RHOA_HUMAN relationship: has_participant CCO:B0020594 ! RHOC_HUMAN relationship: has_participant CCO:B0021069 ! EF1D_HUMAN relationship: has_participant CCO:B0021083 ! Q96I38_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0026448 ! AT2C1_HUMAN relationship: has_participant CCO:B0030172 ! TLR6_HUMAN relationship: has_participant CCO:B0034188 ! TFG_HUMAN relationship: has_participant CCO:B0040467 ! CASP1_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0041769 ! APOL3_HUMAN relationship: has_participant CCO:B0043520 ! CXA1_HUMAN relationship: has_participant CCO:B0048975 ! TGM2_HUMAN relationship: has_participant CCO:B0054296 ! LEG9_HUMAN relationship: has_participant CCO:B0054323 ! TRAF5_HUMAN relationship: has_participant CCO:B0054339 ! TRI38_HUMAN relationship: has_participant CCO:B0054373 ! TR10B_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0054442 ! CFLAR_HUMAN relationship: has_participant CCO:B0054464 ! O43266_HUMAN relationship: has_participant CCO:B0054508 ! TSN6_HUMAN relationship: has_participant CCO:B0054515 ! CIKS_HUMAN relationship: has_participant CCO:B0054702 ! PKHG5_HUMAN relationship: has_participant CCO:B0054942 ! LEG1_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0055188 ! TNR5_HUMAN relationship: has_participant CCO:B0055313 ! TNR3_HUMAN relationship: has_participant CCO:B0055343 ! 5HT2B_HUMAN relationship: has_participant CCO:B0055398 ! TNFL6_HUMAN relationship: has_participant CCO:B0055455 ! TNF10_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0055836 ! BST2_HUMAN relationship: has_participant CCO:B0055881 ! FADD_HUMAN relationship: has_participant CCO:B0056014 ! CASP8_HUMAN relationship: has_participant CCO:B0056116 ! ADIPO_HUMAN relationship: has_participant CCO:B0056158 ! ECM1_HUMAN relationship: has_participant CCO:B0056601 ! GP177_HUMAN relationship: has_participant CCO:B0056880 ! C2D1A_HUMAN relationship: has_participant CCO:B0057158 ! MAVS_HUMAN relationship: has_participant CCO:B0057293 ! TCAM2_HUMAN relationship: has_participant CCO:B0057321 ! TCAM1_HUMAN relationship: has_participant CCO:B0057323 ! ZDH13_HUMAN relationship: has_participant CCO:B0057324 ! ZDH17_HUMAN relationship: has_participant CCO:B0057356 ! CTL2_HUMAN relationship: has_participant CCO:B0057421 ! SHSA5_HUMAN relationship: has_participant CCO:B0057898 ! S35B2_HUMAN relationship: has_participant CCO:B0057914 ! CR032_HUMAN relationship: has_participant CCO:B0057982 ! S20A1_HUMAN relationship: has_participant CCO:B0057996 ! SCTM1_HUMAN relationship: has_participant CCO:B0057997 ! CANT1_HUMAN relationship: has_participant CCO:B0058076 ! LPAR1_HUMAN relationship: has_participant CCO:B0058142 ! MUL1_HUMAN relationship: has_participant CCO:B0058158 ! MIB2_HUMAN relationship: has_participant CCO:B0058229 ! TM101_HUMAN relationship: has_participant CCO:B0058449 ! LITAF_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058512 ! NFIP1_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN relationship: has_participant CCO:B0058679 ! CARD9_HUMAN relationship: has_participant CCO:B0058795 ! NOD2_HUMAN relationship: has_participant CCO:B0058861 ! TMM9B_HUMAN relationship: has_participant CCO:B0058930 ! NFIP2_HUMAN relationship: has_participant CCO:B0059029 ! VAPA_HUMAN relationship: has_participant CCO:B0059106 ! MALT1_HUMAN relationship: has_participant CCO:B0059290 ! NOD1_HUMAN relationship: has_participant CCO:B0059327 ! GPR89_HUMAN relationship: has_participant CCO:B0059335 ! GOT1B_HUMAN relationship: positively_regulates CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:P0002163 name: negative regulation of I-kappaB kinase/NF-kappaB cascade namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade." [GOC:jl] synonym: "down regulation of I-kappaB kinase/NF-kappaB cascade" EXACT [] synonym: "down-regulation of I-kappaB kinase/NF-kappaB cascade" EXACT [] synonym: "downregulation of I-kappaB kinase/NF-kappaB cascade" EXACT [] synonym: "inhibition of I-kappaB kinase/NF-kappaB cascade" NARROW [] xref: GO:0043124 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002161 ! regulation of I-kappaB kinase/NF-kappaB cascade relationship: has_participant CCO:B0055134 ! TNAP3_HUMAN relationship: has_participant CCO:B0055574 ! NAL12_HUMAN relationship: has_participant CCO:B0056094 ! RHOH_HUMAN relationship: has_participant CCO:B0056735 ! OTU7B_HUMAN relationship: has_participant CCO:B0058276 ! BINCA_HUMAN relationship: has_participant CCO:B0059303 ! CARD8_HUMAN relationship: negatively_regulates CCO:P0000768 ! I-kappaB kinase/NF-kappaB cascade [Term] id: CCO:P0002164 name: DNA replication, removal of RNA primer namespace: biological_process def: "Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease." [GOC:jl, PMID:12424238] subset: gosubset_prok synonym: "Okazaki initiator RNA removal" EXACT [] xref: GO:0043137 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0001832 ! DNA replication, Okazaki fragment processing [Term] id: CCO:P0002165 name: translational machinery localization namespace: biological_process def: "Any process by which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." [GOC:jl] subset: gosubset_prok synonym: "establishment and maintenance of translational machinery localization" EXACT [] synonym: "establishment and maintenance of translational protein localization" EXACT [] synonym: "translational protein localization" EXACT [] xref: GO:0043143 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0002166 name: DNA synthesis during double-strand break repair via homologous recombination namespace: biological_process def: "The synthesis of DNA during the process of double-strand break repair via homologous recombination." [GOC:go_curators] subset: gosubset_prok xref: GO:0043150 is_a: CCO:P0000442 ! DNA synthesis during DNA repair [Term] id: CCO:P0002167 name: DNA synthesis during double-strand break repair via single-strand annealing namespace: biological_process def: "The synthesis of DNA during the process of double-strand break repair via single-strand annealing." [GOC:go_curators] subset: gosubset_prok xref: GO:0043151 is_a: CCO:P0000442 ! DNA synthesis during DNA repair [Term] id: CCO:P0002168 name: negative regulation of caspase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of caspase activity." [GOC:jl] synonym: "down regulation of caspase activity" EXACT [] synonym: "down-regulation of caspase activity" EXACT [] synonym: "downregulation of caspase activity" EXACT [] synonym: "inhibition of caspase activation" NARROW [] synonym: "inhibition of caspase activity" NARROW [] synonym: "negative regulation of caspase activation" EXACT [] xref: GO:0001719 xref: GO:0043154 is_a: CCO:P0002179 ! regulation of caspase activity relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001584 ! 1433S_HUMAN relationship: has_participant CCO:B0001675 ! CDN2D_HUMAN relationship: has_participant CCO:B0001806 ! DHC24_HUMAN relationship: has_participant CCO:B0005696 ! DNJB6_HUMAN relationship: has_participant CCO:B0041278 ! HBXIP_HUMAN relationship: has_participant CCO:B0054910 ! GPX1_HUMAN relationship: has_participant CCO:B0054951 ! IFI6_HUMAN relationship: has_participant CCO:B0055674 ! BIRC4_HUMAN [Term] id: CCO:P0002169 name: negative regulation of photosynthesis, light reaction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis." [GOC:jl] synonym: "down regulation of photosynthesis, light reaction" EXACT [] synonym: "down-regulation of photosynthesis, light reaction" EXACT [] synonym: "downregulation of photosynthesis, light reaction" EXACT [] synonym: "inhibition of photosynthesis, light reaction" NARROW [] xref: GO:0043155 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0002101 ! regulation of photosynthesis, light reaction [Term] id: CCO:P0002170 name: rhythmic excitation namespace: biological_process def: "Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit." [GOC:go_curators, ISBN:0195088433] xref: GO:0043179 is_a: CCO:P0003229 ! rhythmic synaptic transmission relationship: has_participant CCO:B0043822 ! EDN1_HUMAN [Term] id: CCO:P0002171 name: rhythmic inhibition namespace: biological_process def: "Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit." [GOC:go_curators] xref: GO:0043180 is_a: CCO:P0003229 ! rhythmic synaptic transmission [Term] id: CCO:P0002172 name: positive regulation of gene-specific transcription namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the DNA-dependent transcription of a specific gene or genes." [GOC:jl] subset: gosubset_prok synonym: "activation of gene-specific transcription" NARROW [] synonym: "stimulation of gene-specific transcription" NARROW [] synonym: "up regulation of gene-specific transcription" EXACT [] synonym: "up-regulation of gene-specific transcription" EXACT [] synonym: "upregulation of gene-specific transcription" EXACT [] xref: GO:0043193 is_a: CCO:P0001644 ! regulation of gene-specific transcription is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0002238 ! MARE3_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005585 ! TIF1B_HUMAN relationship: has_participant CCO:B0019068 ! RORB_HUMAN relationship: has_participant CCO:B0041253 ! PRS8_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0043829 ! PSRC1_HUMAN relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0055095 ! SPI1_HUMAN relationship: has_participant CCO:B0055204 ! SMCA1_HUMAN relationship: has_participant CCO:B0055369 ! GATA4_HUMAN relationship: has_participant CCO:B0055846 ! BPTF_HUMAN relationship: has_participant CCO:B0058447 ! ROAA_HUMAN [Term] id: CCO:P0002173 name: negative regulation of protein complex disassembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "down regulation of protein complex disassembly" EXACT [] synonym: "down-regulation of protein complex disassembly" EXACT [] synonym: "downregulation of protein complex disassembly" EXACT [] synonym: "inhibition of protein complex disassembly" NARROW [] xref: GO:0043242 is_a: CCO:P0002175 ! regulation of protein complex disassembly is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis [Term] id: CCO:P0002174 name: positive regulation of protein complex disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "activation of protein complex disassembly" NARROW [] synonym: "stimulation of protein complex disassembly" NARROW [] synonym: "up regulation of protein complex disassembly" EXACT [] synonym: "up-regulation of protein complex disassembly" EXACT [] synonym: "upregulation of protein complex disassembly" EXACT [] xref: GO:0043243 is_a: CCO:P0002175 ! regulation of protein complex disassembly is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis [Term] id: CCO:P0002175 name: regulation of protein complex disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] subset: gosubset_prok xref: GO:0043244 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0059396 ! IRAK3_HUMAN [Term] id: CCO:P0002176 name: regulation of protein complex assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl] subset: gosubset_prok xref: GO:0043254 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0040425 ! MDN1_HUMAN [Term] id: CCO:P0002177 name: apoptotic cell clearance namespace: biological_process def: "The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte." [GOC:rk, PMID:14685684] comment: Note that unlike mammals or Drosophila, C. elegans (and many lower organisms) do not have professional macrophages/phagocytes, instead cell corpses are engulfed by neighboring cells. Cell types that can function as engulfing cells include hypodermal cells, gonadal sheath cells, pharyngeal muscle cells, and intestinal cells. synonym: "apoptotic cell removal" EXACT [] synonym: "programmed cell clearance" EXACT [] xref: GO:0043277 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000839 ! apoptotic program [Term] id: CCO:P0002178 name: positive regulation of caspase activity namespace: biological_process def: "Any process that activates or increases the activity of a caspase, any of a group of cysteine proteases involved in apoptosis." [GOC:jl] synonym: "activation of caspase activity" NARROW [] synonym: "stimulation of caspase activity" NARROW [] synonym: "up regulation of caspase activity" EXACT [] synonym: "up-regulation of caspase activity" EXACT [] synonym: "upregulation of caspase activity" EXACT [] xref: GO:0043280 is_a: CCO:P0002179 ! regulation of caspase activity relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0058316 ! NALP3_HUMAN relationship: has_participant CCO:B0058945 ! NALP2_HUMAN relationship: has_participant CCO:B0059303 ! CARD8_HUMAN [Term] id: CCO:P0002179 name: regulation of caspase activity namespace: biological_process def: "Any process that modulates the activity of a caspase, any of a group of cysteine proteases involved in apoptosis." [GOC:jl] synonym: "regulation of caspase activation" NARROW [] xref: GO:0043026 xref: GO:0043281 is_a: CCO:P0002131 ! regulation of apoptosis relationship: has_participant CCO:B0055052 ! MGMT_HUMAN [Term] id: CCO:P0002180 name: regulation of mast cell degranulation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of mast cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of mast cell granule exocytosis" EXACT [] xref: GO:0043304 is_a: CCO:P0001750 ! regulation of mast cell activation [Term] id: CCO:P0002181 name: negative regulation of mast cell degranulation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of mast cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of mast cell degranulation" EXACT [] synonym: "down-regulation of mast cell degranulation" EXACT [] synonym: "downregulation of mast cell degranulation" EXACT [] synonym: "inhibition of mast cell degranulation" NARROW [] synonym: "negative regulation of mast cell granule exocytosis" EXACT [] xref: GO:0043305 is_a: CCO:P0001751 ! negative regulation of mast cell activation is_a: CCO:P0002180 ! regulation of mast cell degranulation relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN [Term] id: CCO:P0002182 name: positive regulation of mast cell degranulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mast cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of mast cell degranulation" NARROW [] synonym: "positive regulation of mast cell granule exocytosis" EXACT [] synonym: "stimulation of mast cell degranulation" NARROW [] synonym: "up regulation of mast cell degranulation" EXACT [] synonym: "up-regulation of mast cell degranulation" EXACT [] synonym: "upregulation of mast cell degranulation" EXACT [] xref: GO:0043306 is_a: CCO:P0001752 ! positive regulation of mast cell activation is_a: CCO:P0002180 ! regulation of mast cell degranulation relationship: has_participant CCO:B0042830 ! FCERA_HUMAN relationship: has_participant CCO:B0055217 ! FCERG_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:P0002183 name: regulation of eosinophil degranulation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of eosinophil degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of eosinophil granule exocytosis" EXACT [] xref: GO:0043309 is_a: CCO:P0000562 ! regulation of leukocyte activation [Term] id: CCO:P0002184 name: negative regulation of eosinophil degranulation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of eosinophil degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of eosinophil degranulation" EXACT [] synonym: "down-regulation of eosinophil degranulation" EXACT [] synonym: "downregulation of eosinophil degranulation" EXACT [] synonym: "inhibition of eosinophil degranulation" NARROW [] synonym: "negative regulation of eosinophil granule exocytosis" EXACT [] xref: GO:0043310 is_a: CCO:P0000563 ! negative regulation of leukocyte activation is_a: CCO:P0002183 ! regulation of eosinophil degranulation [Term] id: CCO:P0002185 name: positive regulation of eosinophil degranulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of eosinophil degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of eosinophil degranulation" NARROW [] synonym: "positive regulation of eosinophil granule exocytosis" EXACT [] synonym: "stimulation of eosinophil degranulation" NARROW [] synonym: "up regulation of eosinophil degranulation" EXACT [] synonym: "up-regulation of eosinophil degranulation" EXACT [] synonym: "upregulation of eosinophil degranulation" EXACT [] xref: GO:0043311 is_a: CCO:P0000564 ! positive regulation of leukocyte activation is_a: CCO:P0002183 ! regulation of eosinophil degranulation [Term] id: CCO:P0002186 name: regulation of neutrophil degranulation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of neutrophil degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of neutrophil granule exocytosis" EXACT [] xref: GO:0043313 is_a: CCO:P0000562 ! regulation of leukocyte activation relationship: has_participant CCO:B0058353 ! PRAM_HUMAN [Term] id: CCO:P0002187 name: negative regulation of neutrophil degranulation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of neutrophil degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of neutrophil degranulation" EXACT [] synonym: "down-regulation of neutrophil degranulation" EXACT [] synonym: "downregulation of neutrophil degranulation" EXACT [] synonym: "inhibition of neutrophil degranulation" NARROW [] synonym: "negative regulation of neutrophil granule exocytosis" EXACT [] xref: GO:0043314 is_a: CCO:P0000563 ! negative regulation of leukocyte activation is_a: CCO:P0002186 ! regulation of neutrophil degranulation [Term] id: CCO:P0002188 name: positive regulation of neutrophil degranulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neutrophil degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of neutrophil degranulation" NARROW [] synonym: "positive regulation of neutrophil granule exocytosis" EXACT [] synonym: "stimulation of neutrophil degranulation" NARROW [] synonym: "up regulation of neutrophil degranulation" EXACT [] synonym: "up-regulation of neutrophil degranulation" EXACT [] synonym: "upregulation of neutrophil degranulation" EXACT [] xref: GO:0043315 is_a: CCO:P0000564 ! positive regulation of leukocyte activation is_a: CCO:P0002186 ! regulation of neutrophil degranulation [Term] id: CCO:P0002189 name: cytotoxic T cell degranulation namespace: biological_process def: "The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell." [ISBN:0781735149 "Fundamental Immunology"] synonym: "cytotoxic T cell granule exocytosis" EXACT [] synonym: "cytotoxic T lymphocyte degranulation" EXACT [] synonym: "cytotoxic T lymphocyte granule exocytosis" EXACT [] synonym: "cytotoxic T-cell degranulation" EXACT [] synonym: "cytotoxic T-cell granule exocytosis" EXACT [] synonym: "cytotoxic T-lymphocyte degranulation" EXACT [] synonym: "cytotoxic T-lymphocyte granule exocytosis" EXACT [] xref: GO:0043316 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000487 ! T cell mediated cytotoxicity [Term] id: CCO:P0002190 name: regulation of cytotoxic T cell degranulation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of cytotoxic T cell granule exocytosis" EXACT [] synonym: "regulation of cytotoxic T lymphocyte degranulation" EXACT [] synonym: "regulation of cytotoxic T lymphocyte granule exocytosis" EXACT [] synonym: "regulation of cytotoxic T-cell degranulation" EXACT [] synonym: "regulation of cytotoxic T-cell granule exocytosis" EXACT [] synonym: "regulation of cytotoxic T-lymphocyte degranulation" EXACT [] synonym: "regulation of cytotoxic T-lymphocyte granule exocytosis" EXACT [] xref: GO:0043317 is_a: CCO:P0002981 ! regulation of T cell activation relationship: regulates CCO:P0002189 ! cytotoxic T cell degranulation [Term] id: CCO:P0002191 name: negative regulation of cytotoxic T cell degranulation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of cytotoxic T cell degranulation" EXACT [] synonym: "down-regulation of cytotoxic T cell degranulation" EXACT [] synonym: "downregulation of cytotoxic T cell degranulation" EXACT [] synonym: "inhibition of cytotoxic T cell degranulation" NARROW [] synonym: "negative regulation of cytotoxic T cell granule exocytosis" EXACT [] synonym: "negative regulation of cytotoxic T lymphocyte degranulation" EXACT [] synonym: "negative regulation of cytotoxic T lymphocyte granule exocytosis" EXACT [] synonym: "negative regulation of cytotoxic T-cell degranulation" EXACT [] synonym: "negative regulation of cytotoxic T-cell granule exocytosis" EXACT [] synonym: "negative regulation of cytotoxic T-lymphocyte degranulation" EXACT [] synonym: "negative regulation of cytotoxic T-lymphocyte granule exocytosis" EXACT [] xref: GO:0043318 is_a: CCO:P0002190 ! regulation of cytotoxic T cell degranulation is_a: CCO:P0002986 ! negative regulation of T cell activation relationship: negatively_regulates CCO:P0002189 ! cytotoxic T cell degranulation [Term] id: CCO:P0002192 name: positive regulation of cytotoxic T cell degranulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of cytotoxic T cell degranulation" NARROW [] synonym: "positive regulation of cytotoxic T cell granule exocytosis" EXACT [] synonym: "positive regulation of cytotoxic T lymphocyte degranulation" EXACT [] synonym: "positive regulation of cytotoxic T lymphocyte granule exocytosis" EXACT [] synonym: "positive regulation of cytotoxic T-cell degranulation" EXACT [] synonym: "positive regulation of cytotoxic T-cell granule exocytosis" EXACT [] synonym: "positive regulation of cytotoxic T-lymphocyte degranulation" EXACT [] synonym: "positive regulation of cytotoxic T-lymphocyte granule exocytosis" EXACT [] synonym: "stimulation of cytotoxic T cell degranulation" NARROW [] synonym: "up regulation of cytotoxic T cell degranulation" EXACT [] synonym: "up-regulation of cytotoxic T cell degranulation" EXACT [] synonym: "upregulation of cytotoxic T cell degranulation" EXACT [] xref: GO:0043319 is_a: CCO:P0002190 ! regulation of cytotoxic T cell degranulation is_a: CCO:P0002988 ! positive regulation of T cell activation relationship: positively_regulates CCO:P0002189 ! cytotoxic T cell degranulation [Term] id: CCO:P0002193 name: natural killer cell degranulation namespace: biological_process def: "The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell." [ISBN:0781735149 "Fundamental Immunology"] synonym: "natural killer cell granule exocytosis" EXACT [] synonym: "NK cell degranulation" EXACT [] synonym: "NK cell granule exocytosis" EXACT [] xref: GO:0043320 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002050 ! natural killer cell mediated cytotoxicity [Term] id: CCO:P0002194 name: regulation of natural killer cell degranulation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of natural killer cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of natural killer cell granule exocytosis" EXACT [] synonym: "regulation of NK cell degranulation" EXACT [] synonym: "regulation of NK cell granule exocytosis" EXACT [] xref: GO:0043321 is_a: CCO:P0001656 ! regulation of natural killer cell activation relationship: regulates CCO:P0002193 ! natural killer cell degranulation [Term] id: CCO:P0002195 name: negative regulation of natural killer cell degranulation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of natural killer cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of natural killer cell degranulation" EXACT [] synonym: "down-regulation of natural killer cell degranulation" EXACT [] synonym: "downregulation of natural killer cell degranulation" EXACT [] synonym: "inhibition of natural killer cell degranulation" NARROW [] synonym: "negative regulation of natural killer cell granule exocytosis" EXACT [] synonym: "negative regulation of NK cell degranulation" EXACT [] synonym: "negative regulation of NK cell granule exocytosis" EXACT [] xref: GO:0043322 is_a: CCO:P0001657 ! negative regulation of natural killer cell activation is_a: CCO:P0002194 ! regulation of natural killer cell degranulation relationship: negatively_regulates CCO:P0002193 ! natural killer cell degranulation [Term] id: CCO:P0002196 name: positive regulation of natural killer cell degranulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of natural killer cell degranulation" NARROW [] synonym: "positive regulation of natural killer cell granule exocytosis" EXACT [] synonym: "positive regulation of NK cell degranulation" EXACT [] synonym: "positive regulation of NK cell granule exocytosis" EXACT [] synonym: "stimulation of natural killer cell degranulation" NARROW [] synonym: "up regulation of natural killer cell degranulation" EXACT [] synonym: "up-regulation of natural killer cell degranulation" EXACT [] synonym: "upregulation of natural killer cell degranulation" EXACT [] xref: GO:0043323 is_a: CCO:P0001658 ! positive regulation of natural killer cell activation is_a: CCO:P0002194 ! regulation of natural killer cell degranulation relationship: positively_regulates CCO:P0002193 ! natural killer cell degranulation [Term] id: CCO:P0002197 name: regulation of CD4-positive, alpha beta T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of CD4-positive, alpha beta T cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of CD4-positive T lymphocyte differentiation" EXACT [] synonym: "regulation of CD4-positive T-cell differentiation" EXACT [] synonym: "regulation of CD4-positive T-lymphocyte differentiation" EXACT [] synonym: "regulation of CD4-positive, alpha beta T lymphocyte differentiation" EXACT [] synonym: "regulation of CD4-positive, alpha beta T-cell differentiation" EXACT [] synonym: "regulation of CD4-positive, alpha beta T-lymphocyte differentiation" EXACT [] xref: GO:0043370 is_a: CCO:P0002712 ! regulation of alpha-beta T cell differentiation [Term] id: CCO:P0002198 name: negative regulation of CD4-positive, alpha beta T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate, or extent of CD4-positive, alpha beta T cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] synonym: "down-regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] synonym: "downregulation of CD4-positive, alpha beta T cell differentiation" EXACT [] synonym: "inhibition of CD4-positive, alpha beta T cell differentiation" NARROW [] synonym: "negative regulation of CD4-positive T lymphocyte differentiation" EXACT [] synonym: "negative regulation of CD4-positive T-cell differentiation" EXACT [] synonym: "negative regulation of CD4-positive T-lymphocyte differentiation" EXACT [] synonym: "negative regulation of CD4-positive, alpha beta T lymphocyte differentiation" EXACT [] synonym: "negative regulation of CD4-positive, alpha beta T-cell differentiation" EXACT [] synonym: "negative regulation of CD4-positive, alpha beta T-lymphocyte differentiation" EXACT [] xref: GO:0043371 is_a: CCO:P0002197 ! regulation of CD4-positive, alpha beta T cell differentiation is_a: CCO:P0002714 ! negative regulation of alpha-beta T cell differentiation [Term] id: CCO:P0002199 name: positive regulation of CD4-positive, alpha beta T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha beta T cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of CD4-positive, alpha beta T cell differentiation" NARROW [] synonym: "positive regulation of CD4-positive T lymphocyte differentiation" EXACT [] synonym: "positive regulation of CD4-positive T-cell differentiation" EXACT [] synonym: "positive regulation of CD4-positive T-lymphocyte differentiation" EXACT [] synonym: "positive regulation of CD4-positive, alpha beta T lymphocyte differentiation" EXACT [] synonym: "positive regulation of CD4-positive, alpha beta T-cell differentiation" EXACT [] synonym: "positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation" EXACT [] synonym: "stimulation of CD4-positive, alpha beta T cell differentiation" NARROW [] synonym: "up regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] synonym: "up-regulation of CD4-positive, alpha beta T cell differentiation" EXACT [] synonym: "upregulation of CD4-positive, alpha beta T cell differentiation" EXACT [] xref: GO:0043372 is_a: CCO:P0002197 ! regulation of CD4-positive, alpha beta T cell differentiation is_a: CCO:P0002713 ! positive regulation of alpha-beta T cell differentiation [Term] id: CCO:P0002200 name: regulation of CD8-positive, alpha-beta T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of CD8-positive T lymphocyte differentiation" EXACT [] synonym: "regulation of CD8-positive T-cell differentiation" EXACT [] synonym: "regulation of CD8-positive T-lymphocyte differentiation" EXACT [] synonym: "regulation of CD8-positive, alpha beta T lymphocyte differentiation" EXACT [] synonym: "regulation of CD8-positive, alpha beta T-cell differentiation" EXACT [] synonym: "regulation of CD8-positive, alpha beta T-lymphocyte differentiation" EXACT [] xref: GO:0043376 is_a: CCO:P0002712 ! regulation of alpha-beta T cell differentiation [Term] id: CCO:P0002201 name: negative regulation of CD8-positive, alpha-beta T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] synonym: "down-regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] synonym: "downregulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] synonym: "inhibition of CD8-positive, alpha-beta T cell differentiation" NARROW [] synonym: "negative regulation of CD8-positive T lymphocyte differentiation" EXACT [] synonym: "negative regulation of CD8-positive T-cell differentiation" EXACT [] synonym: "negative regulation of CD8-positive T-lymphocyte differentiation" EXACT [] synonym: "negative regulation of CD8-positive, alpha beta T lymphocyte differentiation" EXACT [] synonym: "negative regulation of CD8-positive, alpha beta T-cell differentiation" EXACT [] synonym: "negative regulation of CD8-positive, alpha beta T-lymphocyte differentiation" EXACT [] xref: GO:0043377 is_a: CCO:P0002200 ! regulation of CD8-positive, alpha-beta T cell differentiation is_a: CCO:P0002714 ! negative regulation of alpha-beta T cell differentiation [Term] id: CCO:P0002202 name: positive regulation of CD8-positive, alpha-beta T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of CD8-positive, alpha-beta T cell differentiation" NARROW [] synonym: "positive regulation of CD8-positive T lymphocyte differentiation" EXACT [] synonym: "positive regulation of CD8-positive T-cell differentiation" EXACT [] synonym: "positive regulation of CD8-positive T-lymphocyte differentiation" EXACT [] synonym: "positive regulation of CD8-positive, alpha beta T lymphocyte differentiation" EXACT [] synonym: "positive regulation of CD8-positive, alpha beta T-cell differentiation" EXACT [] synonym: "positive regulation of CD8-positive, alpha beta T-lymphocyte differentiation" EXACT [] synonym: "stimulation of CD8-positive, alpha-beta T cell differentiation" NARROW [] synonym: "up regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] synonym: "up-regulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] synonym: "upregulation of CD8-positive, alpha-beta T cell differentiation" EXACT [] xref: GO:0043378 is_a: CCO:P0002200 ! regulation of CD8-positive, alpha-beta T cell differentiation is_a: CCO:P0002713 ! positive regulation of alpha-beta T cell differentiation [Term] id: CCO:P0002203 name: regulation of memory T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of memory T cell differentiation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of memory T lymphocyte differentiation" EXACT [] synonym: "regulation of memory T-cell differentiation" EXACT [] synonym: "regulation of memory T-lymphocyte differentiation" EXACT [] xref: GO:0043380 is_a: CCO:P0002394 ! regulation of T cell differentiation relationship: has_participant CCO:B0001603 ! BCL6_HUMAN [Term] id: CCO:P0002204 name: negative regulation of memory T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of memory T cell differentiation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of memory T cell differentiation" EXACT [] synonym: "down-regulation of memory T cell differentiation" EXACT [] synonym: "downregulation of memory T cell differentiation" EXACT [] synonym: "inhibition of memory T cell differentiation" NARROW [] synonym: "negative regulation of memory T lymphocyte differentiation" EXACT [] synonym: "negative regulation of memory T-cell differentiation" EXACT [] synonym: "negative regulation of memory T-lymphocyte differentiation" EXACT [] xref: GO:0043381 is_a: CCO:P0002203 ! regulation of memory T cell differentiation is_a: CCO:P0002395 ! negative regulation of T cell differentiation [Term] id: CCO:P0002205 name: positive regulation of memory T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of memory T cell differentiation." [ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of memory T cell differentiation" NARROW [] synonym: "positive regulation of memory T lymphocyte differentiation" EXACT [] synonym: "positive regulation of memory T-cell differentiation" EXACT [] synonym: "positive regulation of memory T-lymphocyte differentiation" EXACT [] synonym: "stimulation of memory T cell differentiation" NARROW [] synonym: "up regulation of memory T cell differentiation" EXACT [] synonym: "up-regulation of memory T cell differentiation" EXACT [] synonym: "upregulation of memory T cell differentiation" EXACT [] xref: GO:0043382 is_a: CCO:P0002203 ! regulation of memory T cell differentiation is_a: CCO:P0002396 ! positive regulation of T cell differentiation [Term] id: CCO:P0002206 name: regulation of corticotropin-releasing hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion." [GOC:go_curators, PMID:11027914] synonym: "regulation of corticotropin-releasing factor secretion" EXACT [] synonym: "regulation of CRF secretion" EXACT [] synonym: "regulation of CRH secretion" EXACT [] xref: GO:0043397 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0002207 name: steroid hormone mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of a steroid hormone." [PMID:12606724] synonym: "steroid hormone mediated signalling" EXACT [] xref: GO:0043401 is_a: CCO:P0000861 ! hormone-mediated signaling [Term] id: CCO:P0002208 name: glucocorticoid mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of a glucocorticoid hormone." [PMID:15240347] synonym: "glucocorticoid mediated signalling" EXACT [] xref: GO:0043402 is_a: CCO:P0002207 ! steroid hormone mediated signaling [Term] id: CCO:P0002209 name: regulation of MAPKKK cascade namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade." [GOC:go_curators] synonym: "regulation of MAP kinase kinase kinase cascade" EXACT [] synonym: "regulation of mitogen activated protein kinase kinase kinase cascade" EXACT [] synonym: "regulation of mitogen-activated protein kinase kinase kinase cascade" EXACT [] xref: GO:0043408 is_a: CCO:P0001017 ! regulation of protein kinase cascade relationship: has_participant CCO:B0033431 ! NMDE2_HUMAN relationship: has_participant CCO:B0054667 ! RENR_HUMAN relationship: has_participant CCO:B0054828 ! RENI_HUMAN relationship: has_participant CCO:B0055046 ! TIMP2_HUMAN relationship: has_participant CCO:B0055177 ! CD24_HUMAN relationship: regulates CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0002210 name: negative regulation of MAPKKK cascade namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade." [GOC:go_curators] synonym: "down regulation of MAPKKK cascade" EXACT [] synonym: "down-regulation of MAPKKK cascade" EXACT [] synonym: "downregulation of MAPKKK cascade" EXACT [] synonym: "inhibition of MAPKKK cascade" NARROW [] synonym: "negative regulation of MAP kinase kinase kinase cascade" EXACT [] synonym: "negative regulation of mitogen activated protein kinase kinase kinase cascade" EXACT [] synonym: "negative regulation of mitogen-activated protein kinase kinase kinase cascade" EXACT [] xref: GO:0043409 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002209 ! regulation of MAPKKK cascade relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0055545 ! CAV3_HUMAN relationship: has_participant CCO:B0058424 ! P2RX7_HUMAN relationship: negatively_regulates CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0002211 name: positive regulation of MAPKKK cascade namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade." [GOC:go_curators] synonym: "activation of MAPKKK cascade" NARROW [] synonym: "positive regulation of MAP kinase kinase kinase cascade" EXACT [] synonym: "positive regulation of mitogen activated protein kinase kinase kinase cascade" EXACT [] synonym: "positive regulation of mitogen-activated protein kinase kinase kinase cascade" EXACT [] synonym: "stimulation of MAPKKK cascade" NARROW [] synonym: "up regulation of MAPKKK cascade" EXACT [] synonym: "up-regulation of MAPKKK cascade" EXACT [] synonym: "upregulation of MAPKKK cascade" EXACT [] xref: GO:0043410 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002209 ! regulation of MAPKKK cascade relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0042225 ! GRM4_HUMAN relationship: has_participant CCO:B0054564 ! VINEX_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055020 ! ADRB3_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN relationship: has_participant CCO:B0055126 ! IL11_HUMAN relationship: has_participant CCO:B0056926 ! TRAF7_HUMAN relationship: has_participant CCO:B0059243 ! NENF_HUMAN relationship: positively_regulates CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0002212 name: negative regulation of transcription factor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:jl] synonym: "down regulation of transcription factor activity" EXACT [] synonym: "down-regulation of transcription factor activity" EXACT [] synonym: "downregulation of transcription factor activity" EXACT [] synonym: "inhibition of transcription factor activity" NARROW [] xref: GO:0043433 is_a: CCO:P0003021 ! regulation of transcription factor activity relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN relationship: has_participant CCO:B0005472 ! SUMO1_HUMAN relationship: has_participant CCO:B0006002 ! TRIB1_HUMAN relationship: has_participant CCO:B0029351 ! EGLN1_HUMAN relationship: has_participant CCO:B0031899 ! NARFL_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0041401 ! FLNA_HUMAN relationship: has_participant CCO:B0054627 ! PEX14_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0056756 ! SIGIR_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN [Term] id: CCO:P0002213 name: regulation of pentose-phosphate shunt namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process by which glucose is oxidized, coupled to NADPH synthesis." [GOC:jl] synonym: "regulation of pentose phosphate pathway" EXACT [] synonym: "regulation of pentose phosphate shunt" EXACT [] synonym: "regulation of pentose-phosphate pathway" EXACT [] xref: GO:0043456 is_a: CCO:P0000625 ! regulation of nucleotide metabolic process is_a: CCO:P0001284 ! regulation of vitamin metabolic process is_a: CCO:P0002220 ! regulation of cellular carbohydrate catabolic process is_a: CCO:P0003059 ! regulation of coenzyme metabolic process [Term] id: CCO:P0002214 name: regulation of cellular respiration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds." [GOC:jl] xref: GO:0043457 is_a: CCO:P0002217 ! regulation of generation of precursor metabolites and energy [Term] id: CCO:P0002215 name: regulation of rhamnose catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose." [GOC:jl] synonym: "regulation of rhamnose breakdown" EXACT [] synonym: "regulation of rhamnose catabolism" EXACT [] synonym: "regulation of rhamnose degradation" EXACT [] xref: GO:0043463 is_a: CCO:P0002220 ! regulation of cellular carbohydrate catabolic process [Term] id: CCO:P0002216 name: regulation of fermentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP)." [GOC:jl] xref: GO:0043465 is_a: CCO:P0002217 ! regulation of generation of precursor metabolites and energy [Term] id: CCO:P0002217 name: regulation of generation of precursor metabolites and energy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." [GOC:jl] xref: GO:0043467 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0002218 name: regulation of fucose catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose." [GOC:mlg] xref: GO:0043468 is_a: CCO:P0002220 ! regulation of cellular carbohydrate catabolic process [Term] id: CCO:P0002219 name: regulation of D-xylose catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose." [GOC:mlg] xref: GO:0043469 is_a: CCO:P0002220 ! regulation of cellular carbohydrate catabolic process [Term] id: CCO:P0002220 name: regulation of cellular carbohydrate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells." [GOC:jl] subset: gosubset_prok xref: GO:0043471 is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0002221 name: regulation of RNA splicing namespace: biological_process def: "Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." [GOC:jl] xref: GO:0043484 is_a: CCO:P0003068 ! regulation of RNA metabolic process relationship: has_participant CCO:B0005814 ! HNRPF_HUMAN relationship: has_participant CCO:B0054930 ! RU17_HUMAN [Term] id: CCO:P0002222 name: regulation of RNA stability namespace: biological_process def: "Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs." [GOC:jl] subset: gosubset_prok xref: GO:0043487 is_a: CCO:P0001008 ! posttranscriptional regulation of gene expression is_a: CCO:P0003068 ! regulation of RNA metabolic process [Term] id: CCO:P0002223 name: regulation of mRNA stability namespace: biological_process def: "Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs." [GOC:jl] subset: gosubset_prok xref: GO:0043488 is_a: CCO:P0002222 ! regulation of RNA stability relationship: has_participant CCO:B0026498 ! TISB_HUMAN relationship: has_participant CCO:B0031407 ! PAIRB_HUMAN [Term] id: CCO:P0002224 name: RNA stabilization namespace: biological_process def: "Prevention of degradation of RNA molecules." [GOC:go_curators] subset: gosubset_prok xref: GO:0043489 is_a: CCO:P0002222 ! regulation of RNA stability [Term] id: CCO:P0002225 name: protein kinase B signaling cascade namespace: biological_process def: "A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B, which occurs as a result of a single trigger reaction or compound." [GOC:bf] synonym: "AKT signaling cascade" EXACT [] synonym: "AKT signalling cascade" EXACT [] synonym: "PKB signaling cascade" EXACT [] synonym: "PKB signalling cascade" EXACT [] synonym: "protein kinase B signalling cascade" EXACT [] xref: GO:0043491 is_a: CCO:P0000767 ! protein kinase cascade relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0002193 ! KS6B2_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0051810 ! IRS1_HUMAN [Term] id: CCO:P0002226 name: regulation of DNA damage response, signal transduction by p53 class mediator namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:jl] synonym: "regulation of p53 induced by DNA damage response" EXACT [] xref: GO:0043516 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator [Term] id: CCO:P0002227 name: positive regulation of DNA damage response, signal transduction by p53 class mediator namespace: biological_process def: "Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:jl] synonym: "activation of DNA damage response, signal transduction by p53 class mediator" NARROW [] synonym: "positive regulation of p53 induced by DNA damage response" EXACT [] synonym: "stimulation of DNA damage response, signal transduction by p53 class mediator" NARROW [] synonym: "up regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] synonym: "up-regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] synonym: "upregulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] xref: GO:0043517 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002226 ! regulation of DNA damage response, signal transduction by p53 class mediator relationship: has_participant CCO:B0054472 ! MCA3_HUMAN relationship: positively_regulates CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator [Term] id: CCO:P0002228 name: negative regulation of DNA damage response, signal transduction by p53 class mediator namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage." [GOC:jl] synonym: "down regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] synonym: "down-regulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] synonym: "downregulation of DNA damage response, signal transduction by p53 class mediator" EXACT [] synonym: "inhibition of DNA damage response, signal transduction by p53 class mediator" NARROW [] synonym: "negative regulation of p53 induced by DNA damage response" EXACT [] xref: GO:0043518 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002226 ! regulation of DNA damage response, signal transduction by p53 class mediator relationship: negatively_regulates CCO:P0001256 ! DNA damage response, signal transduction by p53 class mediator [Term] id: CCO:P0002229 name: regulation of myosin II filament assembly or disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation or disassembly of a bipolar filament composed of myosin II molecules." [GOC:jl] xref: GO:0043519 is_a: CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis [Term] id: CCO:P0002230 name: regulation of myosin II filament assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules." [GOC:jl] xref: GO:0043520 is_a: CCO:P0002176 ! regulation of protein complex assembly is_a: CCO:P0002229 ! regulation of myosin II filament assembly or disassembly [Term] id: CCO:P0002231 name: regulation of myosin II filament disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules." [GOC:jl] xref: GO:0043521 is_a: CCO:P0001572 ! regulation of cellular protein metabolic process is_a: CCO:P0002175 ! regulation of protein complex disassembly is_a: CCO:P0002229 ! regulation of myosin II filament assembly or disassembly [Term] id: CCO:P0002232 name: regulation of neuron apoptosis namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptosis in neurons." [GOC:go_curators] synonym: "regulation of apoptosis of neuronal cells" EXACT [] synonym: "regulation of apoptosis of neurons" EXACT [] synonym: "regulation of neuron programmed cell death" EXACT [] synonym: "regulation of neuronal cell programmed cell death" EXACT [] synonym: "regulation of programmed cell death of neuronal cells" EXACT [] synonym: "regulation of programmed cell death, neurons" EXACT [] xref: GO:0043523 is_a: CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:P0002233 name: negative regulation of neuron apoptosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis in neurons." [GOC:go_curators] synonym: "down regulation of neuron apoptosis" EXACT [] synonym: "down-regulation of neuron apoptosis" EXACT [] synonym: "downregulation of neuron apoptosis" EXACT [] synonym: "inhibition of neuron apoptosis" NARROW [] synonym: "negative regulation of programmed cell death, neurons" EXACT [] synonym: "neuron survival" NARROW [] xref: GO:0043524 is_a: CCO:P0002148 ! negative regulation of apoptosis is_a: CCO:P0002232 ! regulation of neuron apoptosis relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0005852 ! ERBB3_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0033014 ! SODC_HUMAN relationship: has_participant CCO:B0049794 ! PPT1_HUMAN relationship: has_participant CCO:B0054687 ! WFS1_HUMAN relationship: has_participant CCO:B0055323 ! GDNF_HUMAN relationship: has_participant CCO:B0055405 ! GSH0_HUMAN [Term] id: CCO:P0002234 name: positive regulation of neuron apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptosis." [GOC:go_curators] synonym: "activation of neuron apoptosis" NARROW [] synonym: "positive regulation of programmed cell death, neurons" EXACT [] synonym: "stimulation of neuron apoptosis" NARROW [] synonym: "up regulation of neuron apoptosis" EXACT [] synonym: "up-regulation of neuron apoptosis" EXACT [] synonym: "upregulation of neuron apoptosis" EXACT [] xref: GO:0043525 is_a: CCO:P0002147 ! positive regulation of apoptosis is_a: CCO:P0002232 ! regulation of neuron apoptosis relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0001723 ! BAX_HUMAN relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN relationship: has_participant CCO:B0057558 ! PCSK9_HUMAN [Term] id: CCO:P0002235 name: neuroprotection namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptosis in the nervous system. It may stop or prevent or reduce the rate of cell death by apoptosis and it is activated by stress to counteract death signals in central nervous systems. Different neuroprotective mechanisms may be activated to combat distinct types of cellular stress, ERK pathway is one of several neuroprotective mechanisms and it is a model system to study neuronal apoptosis, which may contribute to several neurodegenerative diseases and aging-related neuron loss." [MeSH:G04.335.139.160, PMID:10208444, PMID:11909981, PMID:15905876] xref: GO:0043526 is_a: CCO:P0002232 ! regulation of neuron apoptosis relationship: has_participant CCO:B0001806 ! DHC24_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0042225 ! GRM4_HUMAN relationship: has_participant CCO:B0055732 ! ATP7A_HUMAN relationship: has_participant CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:P0002236 name: regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] xref: GO:0043535 is_a: CCO:P0001001 ! regulation of endothelial cell migration relationship: has_participant CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:P0002237 name: positive regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "activation of blood vessel endothelial cell migration" NARROW [] synonym: "stimulation of blood vessel endothelial cell migration" NARROW [] synonym: "up regulation of blood vessel endothelial cell migration" EXACT [] synonym: "up-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "upregulation of blood vessel endothelial cell migration" EXACT [] xref: GO:0043536 is_a: CCO:P0001002 ! positive regulation of endothelial cell migration is_a: CCO:P0002236 ! regulation of blood vessel endothelial cell migration relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0056332 ! AMOT_HUMAN [Term] id: CCO:P0002238 name: negative regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "down regulation of blood vessel endothelial cell migration" EXACT [] synonym: "down-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "downregulation of blood vessel endothelial cell migration" EXACT [] synonym: "inhibition of blood vessel endothelial cell migration" NARROW [] xref: GO:0043537 is_a: CCO:P0001003 ! negative regulation of endothelial cell migration is_a: CCO:P0002236 ! regulation of blood vessel endothelial cell migration relationship: has_participant CCO:B0054826 ! PLMN_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN [Term] id: CCO:P0002239 name: regulation of actin phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule." [GOC:go_curators] xref: GO:0043538 is_a: CCO:P0000500 ! regulation of protein amino acid phosphorylation is_a: CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis [Term] id: CCO:P0002240 name: regulation of translation in response to stress namespace: biological_process def: "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:jl] synonym: "translational stress response" EXACT [] xref: GO:0043555 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0002241 name: regulation of translation in response to oxidative stress namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl] xref: GO:0043556 is_a: CCO:P0002240 ! regulation of translation in response to stress [Term] id: CCO:P0002242 name: regulation of translation in response to osmotic stress namespace: biological_process def: "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:jl] xref: GO:0043557 is_a: CCO:P0002240 ! regulation of translation in response to stress [Term] id: CCO:P0002243 name: regulation of translational initiation in response to stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress." [GOC:jl] xref: GO:0043558 is_a: CCO:P0000661 ! regulation of translational initiation is_a: CCO:P0002240 ! regulation of translation in response to stress relationship: has_participant CCO:B0041436 ! IF2A_HUMAN [Term] id: CCO:P0002244 name: regulation of translational initiation in response to osmotic stress namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." [GOC:dph, GOC:jl, GOC:tb] xref: GO:0043561 is_a: CCO:P0002242 ! regulation of translation in response to osmotic stress is_a: CCO:P0002243 ! regulation of translational initiation in response to stress [Term] id: CCO:P0002245 name: regulation of insulin-like growth factor receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling." [GOC:bf] synonym: "regulation of IGF receptor signaling pathway" EXACT [] synonym: "regulation of IGF receptor signalling pathway" EXACT [] synonym: "regulation of insulin-like growth factor receptor signalling pathway" EXACT [] xref: GO:0043567 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0002755 ! insulin-like growth factor receptor signaling pathway [Term] id: CCO:P0002246 name: positive regulation of insulin-like growth factor receptor signaling pathway namespace: biological_process def: "Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling." [GOC:bf] synonym: "activation of insulin-like growth factor receptor signaling pathway" NARROW [] synonym: "positive regulation of IGF receptor signaling pathway" EXACT [] synonym: "positive regulation of IGF receptor signalling pathway" EXACT [] synonym: "positive regulation of insulin-like growth factor receptor signalling pathway" EXACT [] synonym: "stimulation of insulin-like growth factor receptor signaling pathway" NARROW [] synonym: "up regulation of insulin-like growth factor receptor signaling pathway" EXACT [] synonym: "up-regulation of insulin-like growth factor receptor signaling pathway" EXACT [] synonym: "upregulation of insulin-like growth factor receptor signaling pathway" EXACT [] xref: GO:0043568 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002245 ! regulation of insulin-like growth factor receptor signaling pathway relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN relationship: positively_regulates CCO:P0002755 ! insulin-like growth factor receptor signaling pathway [Term] id: CCO:P0002247 name: negative regulation of insulin-like growth factor receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling." [GOC:bf] synonym: "down regulation of insulin-like growth factor receptor signaling pathway" EXACT [] synonym: "down-regulation of insulin-like growth factor receptor signaling pathway" EXACT [] synonym: "downregulation of insulin-like growth factor receptor signaling pathway" EXACT [] synonym: "inhibition of insulin-like growth factor receptor signaling pathway" NARROW [] synonym: "negative regulation of IGF receptor signaling pathway" EXACT [] synonym: "negative regulation of IGF receptor signalling pathway" EXACT [] synonym: "negative regulation of insulin-like growth factor receptor signalling pathway" EXACT [] xref: GO:0043569 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002245 ! regulation of insulin-like growth factor receptor signaling pathway relationship: has_participant CCO:B0054617 ! CILP1_HUMAN relationship: has_participant CCO:B0055174 ! IBP5_HUMAN relationship: negatively_regulates CCO:P0002755 ! insulin-like growth factor receptor signaling pathway [Term] id: CCO:P0002248 name: keratinocyte proliferation namespace: biological_process def: "The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin." [CL:0000311] xref: GO:0043616 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0021657 ! K22E_HUMAN relationship: has_participant CCO:B0039858 ! KLK8_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN [Term] id: CCO:P0002249 name: regulation of transcription from RNA polymerase II promoter in response to stress namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:jl] xref: GO:0043618 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter is_a: CCO:P0002251 ! regulation of transcription in response to stress [Term] id: CCO:P0002250 name: regulation of transcription from RNA polymerase II promoter in response to oxidative stress namespace: biological_process def: "Modulation of the frequency, rate or extent of transcription from an from RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl] xref: GO:0043619 is_a: CCO:P0002249 ! regulation of transcription from RNA polymerase II promoter in response to stress relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN [Term] id: CCO:P0002251 name: regulation of transcription in response to stress namespace: biological_process def: "Modulation of the frequency, rate or extent of transcription as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:jl] xref: GO:0043620 is_a: CCO:P0002369 ! regulation of transcription [Term] id: CCO:P0002252 name: engulfment of apoptotic cell namespace: biological_process def: "The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte." [GOC:rk, PMID:15536015] synonym: "engulfment of apoptotic cell corpse" EXACT [] synonym: "engulfment of cell corpse" EXACT [] xref: GO:0043652 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002177 ! apoptotic cell clearance [Term] id: CCO:P0002253 name: mitochondrial fragmentation during apoptosis namespace: biological_process def: "The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form." [GOC:rk, PMID:12867994] synonym: "mitochondrial fission during apoptosis" EXACT [] xref: GO:0043653 is_a: CCO:P0000844 ! apoptotic mitochondrial changes relationship: has_participant CCO:B0054320 ! DNM1L_HUMAN [Term] id: CCO:P0002254 name: recognition of apoptotic cell namespace: biological_process def: "The process by which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis." [GOC:rk, PMID:15536015] synonym: "detection of apoptotic cell" EXACT [] synonym: "detection of apoptotic cell corpse" EXACT [] synonym: "detection of cell corpse" EXACT [] synonym: "recognition of apoptotic cell corpse" EXACT [] synonym: "recognition of cell corpse" EXACT [] xref: GO:0043654 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0002177 ! apoptotic cell clearance [Term] id: CCO:P0002255 name: modulation by host of viral transcription namespace: biological_process def: "Any process by which a host organism modulates the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA." [GOC:jl] synonym: "regulation by host of viral transcription" EXACT [] synonym: "regulation of viral transcription by host " EXACT [] xref: GO:0043921 is_a: CCO:P0003212 ! modulation by host of symbiont transcription [Term] id: CCO:P0002256 name: negative regulation by host of viral transcription namespace: biological_process def: "Any process by which a host organism stops, prevents or reduces the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA." [GOC:jl] synonym: "negative regulation of viral transcription by host" EXACT [] xref: GO:0043922 is_a: CCO:P0001129 ! negative regulation of transcription is_a: CCO:P0002255 ! modulation by host of viral transcription [Term] id: CCO:P0002257 name: positive regulation by host of viral transcription namespace: biological_process def: "Any process by which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA." [GOC:jl] synonym: "positive regulation of viral transcription by host" EXACT [] xref: GO:0043923 is_a: CCO:P0002255 ! modulation by host of viral transcription is_a: CCO:P0002625 ! positive regulation of transcription [Term] id: CCO:P0002258 name: DNA replication proofreading namespace: biological_process def: "Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity." [GOC:ai] subset: gosubset_prok xref: GO:0045004 is_a: CCO:P0002259 ! maintenance of fidelity during DNA-dependent DNA replication [Term] id: CCO:P0002259 name: maintenance of fidelity during DNA-dependent DNA replication namespace: biological_process def: "The correction of errors made during DNA replication by either intrinsic DNA polymerase proofreading activity or via mismatch repair." [GOC:ai] subset: gosubset_prok xref: GO:0045005 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0002260 name: negative regulation of transcription by carbon catabolites namespace: biological_process def: "Any process involving carbon catabolites that stops, prevents or reduces the rate of transcription. Carbon catabolite repression is a mechanism of genetic regulation in bacteria in which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:11018147] subset: gosubset_prok synonym: "carbon catabolite repression" EXACT [] synonym: "down regulation of transcription by carbon catabolites" EXACT [] synonym: "down-regulation of transcription by carbon catabolites" EXACT [] synonym: "downregulation of transcription by carbon catabolites" EXACT [] synonym: "inhibition of transcription by carbon catabolites" NARROW [] xref: GO:0045013 is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent is_a: CCO:P0002662 ! regulation of transcription by carbon catabolites [Term] id: CCO:P0002261 name: negative regulation of transcription by glucose namespace: biological_process def: "Any process involving glucose that stops, prevents or reduces the rate of transcription. The presence of glucose in the growth medium inhibits the synthesis of certain enzymes in bacteria growing on the medium. For example, transcription of some catabolic operons is under negative control by specific repressors and glucose is an anti-inducer of xylose utilization and glycerol kinase." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:11018147] subset: gosubset_prok synonym: "down regulation of transcription by glucose" EXACT [] synonym: "down-regulation of transcription by glucose" EXACT [] synonym: "downregulation of transcription by glucose" EXACT [] synonym: "glucose effect" EXACT [] synonym: "glucose repression" EXACT [] synonym: "inhibition of transcription by glucose" NARROW [] xref: GO:0045014 is_a: CCO:P0002260 ! negative regulation of transcription by carbon catabolites is_a: CCO:P0002677 ! regulation of transcription by glucose relationship: has_participant CCO:B0002148 ! CHM1A_HUMAN [Term] id: CCO:P0002262 name: negative regulation of nitric oxide biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] synonym: "down regulation of nitric oxide biosynthetic process" EXACT [] synonym: "down-regulation of nitric oxide biosynthetic process" EXACT [] synonym: "downregulation of nitric oxide biosynthetic process" EXACT [] synonym: "inhibition of nitric oxide biosynthetic process" NARROW [] synonym: "negative regulation of nitric oxide anabolism" EXACT [] synonym: "negative regulation of nitric oxide biosynthesis" EXACT [] synonym: "negative regulation of nitric oxide formation" EXACT [] synonym: "negative regulation of nitric oxide synthesis" EXACT [] xref: GO:0045019 is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0002367 ! regulation of nitric oxide biosynthetic process relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0054902 ! AGAL_HUMAN [Term] id: CCO:P0002263 name: sensory organ precursor cell division namespace: biological_process def: "The series of 4 asymmetric divisions undergone by the sensory organ precursor cells to generate the four external sensory organ cells (the socket, shaft, sheath cells and the external sense neuron), together with one multidendritic neuron." [PMID:11171389] synonym: "sense organ precursor cell division" EXACT [GOC:dph] xref: GO:0045035 is_a: CCO:P0000821 ! asymmetric cell division [Term] id: CCO:P0002264 name: regulation of interferon-gamma biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma." [GOC:go_curators] synonym: "regulation of interferon-gamma anabolism" EXACT [] synonym: "regulation of interferon-gamma biosynthesis" EXACT [] synonym: "regulation of interferon-gamma formation" EXACT [] synonym: "regulation of interferon-gamma synthesis" EXACT [] xref: GO:0045072 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002265 name: regulation of chemokine biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines." [GOC:go_curators] synonym: "regulation of chemokine anabolism" EXACT [] synonym: "regulation of chemokine biosynthesis" EXACT [] synonym: "regulation of chemokine formation" EXACT [] synonym: "regulation of chemokine synthesis" EXACT [] xref: GO:0045073 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002266 name: regulation of interleukin-10 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10." [GOC:go_curators] synonym: "regulation of IL-10 biosynthesis" EXACT [] synonym: "regulation of IL-10 biosynthetic process" EXACT [] synonym: "regulation of interleukin-10 anabolism" EXACT [] synonym: "regulation of interleukin-10 biosynthesis" EXACT [] synonym: "regulation of interleukin-10 formation" EXACT [] synonym: "regulation of interleukin-10 synthesis" EXACT [] xref: GO:0045074 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002267 name: regulation of interleukin-12 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12." [GOC:go_curators] synonym: "regulation of IL-12 biosynthesis" EXACT [] synonym: "regulation of IL-12 biosynthetic process" EXACT [] synonym: "regulation of interleukin-12 anabolism" EXACT [] synonym: "regulation of interleukin-12 biosynthesis" EXACT [] synonym: "regulation of interleukin-12 formation" EXACT [] synonym: "regulation of interleukin-12 synthesis" EXACT [] xref: GO:0045075 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: has_participant CCO:B0056876 ! MAST2_HUMAN [Term] id: CCO:P0002268 name: regulation of interleukin-2 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2." [GOC:go_curators] synonym: "regulation of IL-2 biosynthesis" EXACT [] synonym: "regulation of IL-2 biosynthetic process" EXACT [] synonym: "regulation of interleukin-2 anabolism" EXACT [] synonym: "regulation of interleukin-2 biosynthesis" EXACT [] synonym: "regulation of interleukin-2 formation" EXACT [] synonym: "regulation of interleukin-2 synthesis" EXACT [] xref: GO:0045076 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002269 name: negative regulation of interferon-gamma biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma." [GOC:go_curators] synonym: "down regulation of interferon-gamma biosynthetic process" EXACT [] synonym: "down-regulation of interferon-gamma biosynthetic process" EXACT [] synonym: "downregulation of interferon-gamma biosynthetic process" EXACT [] synonym: "inhibition of interferon-gamma biosynthetic process" NARROW [] synonym: "negative regulation of interferon-gamma anabolism" EXACT [] synonym: "negative regulation of interferon-gamma biosynthesis" EXACT [] synonym: "negative regulation of interferon-gamma formation" EXACT [] synonym: "negative regulation of interferon-gamma synthesis" EXACT [] xref: GO:0045077 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002264 ! regulation of interferon-gamma biosynthetic process relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN [Term] id: CCO:P0002270 name: positive regulation of interferon-gamma biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma." [GOC:go_curators] synonym: "activation of interferon-gamma biosynthetic process" NARROW [] synonym: "positive regulation of interferon-gamma anabolism" EXACT [] synonym: "positive regulation of interferon-gamma biosynthesis" EXACT [] synonym: "positive regulation of interferon-gamma formation" EXACT [] synonym: "positive regulation of interferon-gamma synthesis" EXACT [] synonym: "stimulation of interferon-gamma biosynthetic process" NARROW [] synonym: "up regulation of interferon-gamma biosynthetic process" EXACT [] synonym: "up-regulation of interferon-gamma biosynthetic process" EXACT [] synonym: "upregulation of interferon-gamma biosynthetic process" EXACT [] xref: GO:0045078 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002264 ! regulation of interferon-gamma biosynthetic process relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0055972 ! IL27B_HUMAN relationship: has_participant CCO:B0056685 ! CD276_HUMAN relationship: has_participant CCO:B0057596 ! IL27A_HUMAN relationship: has_participant CCO:B0058783 ! IL21_HUMAN relationship: has_participant CCO:B0058891 ! TLR9_HUMAN relationship: has_participant CCO:B0058892 ! TLR8_HUMAN relationship: has_participant CCO:B0058964 ! TLR7_HUMAN [Term] id: CCO:P0002271 name: negative regulation of chemokine biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines." [GOC:go_curators] synonym: "down regulation of chemokine biosynthetic process" EXACT [] synonym: "down-regulation of chemokine biosynthetic process" EXACT [] synonym: "downregulation of chemokine biosynthetic process" EXACT [] synonym: "inhibition of chemokine biosynthetic process" NARROW [] synonym: "negative regulation of chemokine anabolism" EXACT [] synonym: "negative regulation of chemokine biosynthesis" EXACT [] synonym: "negative regulation of chemokine formation" EXACT [] synonym: "negative regulation of chemokine synthesis" EXACT [] xref: GO:0045079 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002265 ! regulation of chemokine biosynthetic process relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054926 ! ELNE_HUMAN relationship: has_participant CCO:B0056756 ! SIGIR_HUMAN [Term] id: CCO:P0002272 name: positive regulation of chemokine biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines." [GOC:go_curators] synonym: "activation of chemokine biosynthetic process" NARROW [] synonym: "positive regulation of chemokine anabolism" EXACT [] synonym: "positive regulation of chemokine biosynthesis" EXACT [] synonym: "positive regulation of chemokine formation" EXACT [] synonym: "positive regulation of chemokine synthesis" EXACT [] synonym: "stimulation of chemokine biosynthetic process" NARROW [] synonym: "up regulation of chemokine biosynthetic process" EXACT [] synonym: "up-regulation of chemokine biosynthetic process" EXACT [] synonym: "upregulation of chemokine biosynthetic process" EXACT [] xref: GO:0045080 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002265 ! regulation of chemokine biosynthetic process relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN [Term] id: CCO:P0002273 name: negative regulation of interleukin-10 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10." [GOC:go_curators] synonym: "down regulation of interleukin-10 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-10 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-10 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-10 biosynthetic process" NARROW [] synonym: "negative regulation of IL-10 biosynthesis" EXACT [] synonym: "negative regulation of IL-10 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-10 anabolism" EXACT [] synonym: "negative regulation of interleukin-10 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-10 formation" EXACT [] synonym: "negative regulation of interleukin-10 synthesis" EXACT [] xref: GO:0045081 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002266 ! regulation of interleukin-10 biosynthetic process [Term] id: CCO:P0002274 name: positive regulation of interleukin-10 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10." [GOC:go_curators] synonym: "activation of interleukin-10 biosynthetic process" NARROW [] synonym: "positive regulation of IL-10 biosynthesis" EXACT [] synonym: "positive regulation of IL-10 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-10 anabolism" EXACT [] synonym: "positive regulation of interleukin-10 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-10 formation" EXACT [] synonym: "positive regulation of interleukin-10 synthesis" EXACT [] synonym: "stimulation of interleukin-10 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-10 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-10 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-10 biosynthetic process" EXACT [] xref: GO:0045082 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002266 ! regulation of interleukin-10 biosynthetic process relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0056056 ! IRF4_HUMAN relationship: has_participant CCO:B0058411 ! Q99419_HUMAN [Term] id: CCO:P0002275 name: negative regulation of interleukin-12 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12." [GOC:go_curators] synonym: "down regulation of interleukin-12 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-12 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-12 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-12 biosynthetic process" NARROW [] synonym: "negative regulation of IL-12 biosynthesis" EXACT [] synonym: "negative regulation of IL-12 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-12 anabolism" EXACT [] synonym: "negative regulation of interleukin-12 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-12 formation" EXACT [] synonym: "negative regulation of interleukin-12 synthesis" EXACT [] xref: GO:0045083 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002267 ! regulation of interleukin-12 biosynthetic process [Term] id: CCO:P0002276 name: positive regulation of interleukin-12 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12." [GOC:go_curators] synonym: "activation of interleukin-12 biosynthetic process" NARROW [] synonym: "positive regulation of IL-12 biosynthesis" EXACT [] synonym: "positive regulation of IL-12 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-12 anabolism" EXACT [] synonym: "positive regulation of interleukin-12 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-12 formation" EXACT [] synonym: "positive regulation of interleukin-12 synthesis" EXACT [] synonym: "stimulation of interleukin-12 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-12 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-12 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-12 biosynthetic process" EXACT [] xref: GO:0045084 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002267 ! regulation of interleukin-12 biosynthetic process relationship: has_participant CCO:B0001510 ! IRF1_HUMAN relationship: has_participant CCO:B0022071 ! TLR4_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0055770 ! TNFC_HUMAN [Term] id: CCO:P0002277 name: negative regulation of interleukin-2 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2." [GOC:go_curators] synonym: "down regulation of interleukin-2 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-2 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-2 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-2 biosynthetic process" NARROW [] synonym: "negative regulation of IL-2 biosynthesis" EXACT [] synonym: "negative regulation of IL-2 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-2 anabolism" EXACT [] synonym: "negative regulation of interleukin-2 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-2 formation" EXACT [] synonym: "negative regulation of interleukin-2 synthesis" EXACT [] xref: GO:0045085 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002268 ! regulation of interleukin-2 biosynthetic process relationship: has_participant CCO:B0055103 ! LAG3_HUMAN relationship: has_participant CCO:B0055282 ! SFTPD_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN [Term] id: CCO:P0002278 name: positive regulation of interleukin-2 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2." [GOC:go_curators] synonym: "activation of interleukin-2 biosynthetic process" NARROW [] synonym: "positive regulation of IL-2 biosynthesis" EXACT [] synonym: "positive regulation of IL-2 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-2 anabolism" EXACT [] synonym: "positive regulation of interleukin-2 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-2 formation" EXACT [] synonym: "positive regulation of interleukin-2 synthesis" EXACT [] synonym: "stimulation of interleukin-2 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-2 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-2 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-2 biosynthetic process" EXACT [] xref: GO:0045086 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002268 ! regulation of interleukin-2 biosynthetic process relationship: has_participant CCO:B0001508 ! CD28_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001927 ! Q70WG0_HUMAN relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0055268 ! CD80_HUMAN relationship: has_participant CCO:B0055346 ! CD86_HUMAN relationship: has_participant CCO:B0056056 ! IRF4_HUMAN relationship: has_participant CCO:B0058117 ! GLMN_HUMAN relationship: has_participant CCO:B0058411 ! Q99419_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN [Term] id: CCO:P0002279 name: regulation of intermediate filament polymerization and/or depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases." [ISBN:0716731363] xref: GO:0045108 is_a: CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0002280 name: regulation of integrin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins." [GOC:go_curators] synonym: "regulation of integrin anabolism" EXACT [] synonym: "regulation of integrin biosynthesis" EXACT [] synonym: "regulation of integrin formation" EXACT [] synonym: "regulation of integrin synthesis" EXACT [] xref: GO:0045113 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0005461 ! S10A9_HUMAN [Term] id: CCO:P0002281 name: regulation of beta 2 integrin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins." [GOC:go_curators] synonym: "regulation of beta 2 integrin anabolism" EXACT [] synonym: "regulation of beta 2 integrin biosynthesis" EXACT [] synonym: "regulation of beta 2 integrin formation" EXACT [] synonym: "regulation of beta 2 integrin synthesis" EXACT [] xref: GO:0045115 is_a: CCO:P0002280 ! regulation of integrin biosynthetic process [Term] id: CCO:P0002282 name: initiation of acetate catabolic process by acetate namespace: biological_process def: "The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [PMID:11741859] subset: gosubset_prok synonym: "initiation of acetate breakdown by acetate" EXACT [] synonym: "initiation of acetate degradation by acetate" EXACT [] xref: GO:0045146 is_a: CCO:P0002155 ! initiation of acetate catabolic process [Term] id: CCO:P0002283 name: regulation of initiation of acetate catabolic process by acetate namespace: biological_process def: "Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of initiation of acetate breakdown by acetate" EXACT [] synonym: "regulation of initiation of acetate degradation by acetate" EXACT [] xref: GO:0045147 is_a: CCO:P0002525 ! regulation of acetate catabolic process relationship: regulates CCO:P0002282 ! initiation of acetate catabolic process by acetate [Term] id: CCO:P0002284 name: regulation of isotype switching namespace: biological_process def: "Any process that modulates the frequency, rate or extent of isotype switching." [GOC:ai] synonym: "regulation of class switch recombination" EXACT [] synonym: "regulation of class switching" EXACT [] synonym: "regulation of isotype switch recombination" EXACT [] xref: GO:0045191 is_a: CCO:P0000398 ! regulation of DNA recombination is_a: CCO:P0002982 ! regulation of B cell activation relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0055142 ! IL10_HUMAN [Term] id: CCO:P0002285 name: regulation of FasL biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL." [GOC:go_curators] synonym: "regulation of FasL anabolism" EXACT [] synonym: "regulation of FasL biosynthesis" EXACT [] synonym: "regulation of FasL formation" EXACT [] synonym: "regulation of FasL synthesis" EXACT [] xref: GO:0045219 is_a: CCO:P0000982 ! regulation of glycoprotein biosynthetic process [Term] id: CCO:P0002286 name: positive regulation of FasL biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL." [GOC:go_curators] synonym: "activation of FasL biosynthetic process" NARROW [] synonym: "positive regulation of FasL anabolism" EXACT [] synonym: "positive regulation of FasL biosynthesis" EXACT [] synonym: "positive regulation of FasL formation" EXACT [] synonym: "positive regulation of FasL synthesis" EXACT [] synonym: "stimulation of FasL biosynthetic process" NARROW [] synonym: "up regulation of FasL biosynthetic process" EXACT [] synonym: "up-regulation of FasL biosynthetic process" EXACT [] synonym: "upregulation of FasL biosynthetic process" EXACT [] xref: GO:0045220 is_a: CCO:P0000983 ! positive regulation of glycoprotein biosynthetic process is_a: CCO:P0002285 ! regulation of FasL biosynthetic process is_a: CCO:P0002524 ! positive regulation of translation [Term] id: CCO:P0002287 name: negative regulation of FasL biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL." [GOC:go_curators] synonym: "down regulation of FasL biosynthetic process" EXACT [] synonym: "down-regulation of FasL biosynthetic process" EXACT [] synonym: "downregulation of FasL biosynthetic process" EXACT [] synonym: "inhibition of FasL biosynthetic process" NARROW [] synonym: "negative regulation of FasL anabolism" EXACT [] synonym: "negative regulation of FasL biosynthesis" EXACT [] synonym: "negative regulation of FasL formation" EXACT [] synonym: "negative regulation of FasL synthesis" EXACT [] xref: GO:0045221 is_a: CCO:P0000984 ! negative regulation of glycoprotein biosynthetic process is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0002285 ! regulation of FasL biosynthetic process [Term] id: CCO:P0002288 name: regulation of CD4 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "regulation of CD4 anabolism" EXACT [] synonym: "regulation of CD4 biosynthesis" EXACT [] synonym: "regulation of CD4 formation" EXACT [] synonym: "regulation of CD4 synthesis" EXACT [] xref: GO:0045223 is_a: CCO:P0000982 ! regulation of glycoprotein biosynthetic process [Term] id: CCO:P0002289 name: positive regulation of CD4 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "activation of CD4 biosynthetic process" NARROW [] synonym: "positive regulation of CD4 anabolism" EXACT [] synonym: "positive regulation of CD4 biosynthesis" EXACT [] synonym: "positive regulation of CD4 formation" EXACT [] synonym: "positive regulation of CD4 synthesis" EXACT [] synonym: "stimulation of CD4 biosynthetic process" NARROW [] synonym: "up regulation of CD4 biosynthetic process" EXACT [] synonym: "up-regulation of CD4 biosynthetic process" EXACT [] synonym: "upregulation of CD4 biosynthetic process" EXACT [] xref: GO:0045224 is_a: CCO:P0000983 ! positive regulation of glycoprotein biosynthetic process is_a: CCO:P0002288 ! regulation of CD4 biosynthetic process is_a: CCO:P0002524 ! positive regulation of translation [Term] id: CCO:P0002290 name: negative regulation of CD4 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "down regulation of CD4 biosynthetic process" EXACT [] synonym: "down-regulation of CD4 biosynthetic process" EXACT [] synonym: "downregulation of CD4 biosynthetic process" EXACT [] synonym: "inhibition of CD4 biosynthetic process" NARROW [] synonym: "negative regulation of CD4 anabolism" EXACT [] synonym: "negative regulation of CD4 biosynthesis" EXACT [] synonym: "negative regulation of CD4 formation" EXACT [] synonym: "negative regulation of CD4 synthesis" EXACT [] xref: GO:0045225 is_a: CCO:P0000984 ! negative regulation of glycoprotein biosynthetic process is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0002288 ! regulation of CD4 biosynthetic process [Term] id: CCO:P0002291 name: regulation of establishment of competence for transformation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process by which a cell becomes able to take up and incorporate extracellular DNA into its genome." [GOC:mlg] subset: gosubset_prok synonym: "regulator of establishment of competence for transformation activity" RELATED [] xref: GO:0045304 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0002292 name: regulation of compound eye photoreceptor development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor development." [GOC:bf] synonym: "regulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] xref: GO:0045314 is_a: CCO:P0002063 ! regulation of eye photoreceptor cell development relationship: part_of CCO:P0002695 ! regulation of photoreceptor cell differentiation [Term] id: CCO:P0002293 name: positive regulation of compound eye photoreceptor development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development." [GOC:bf] synonym: "activation of eye photoreceptor development (sensu Endopterygota)" NARROW [] synonym: "positive regulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] synonym: "stimulation of eye photoreceptor development (sensu Endopterygota)" NARROW [] synonym: "up regulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] synonym: "up-regulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] synonym: "upregulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] xref: GO:0045315 is_a: CCO:P0002064 ! positive regulation of eye photoreceptor cell development is_a: CCO:P0002292 ! regulation of compound eye photoreceptor development [Term] id: CCO:P0002294 name: negative regulation of compound eye photoreceptor development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye photoreceptor development." [GOC:bf] synonym: "down regulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] synonym: "down-regulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] synonym: "downregulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] synonym: "inhibition of eye photoreceptor development (sensu Endopterygota)" NARROW [] synonym: "negative regulation of eye photoreceptor development (sensu Endopterygota)" EXACT [] xref: GO:0045316 is_a: CCO:P0002065 ! negative regulation of eye photoreceptor cell development is_a: CCO:P0002292 ! regulation of compound eye photoreceptor development [Term] id: CCO:P0002295 name: regulation of interferon-alpha biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha." [GOC:go_curators] synonym: "regulation of interferon-alpha anabolism" EXACT [] synonym: "regulation of interferon-alpha biosynthesis" EXACT [] synonym: "regulation of interferon-alpha formation" EXACT [] synonym: "regulation of interferon-alpha synthesis" EXACT [] xref: GO:0045354 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002296 name: negative regulation of interferon-alpha biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha." [GOC:go_curators] synonym: "down regulation of interferon-alpha biosynthetic process" EXACT [] synonym: "down-regulation of interferon-alpha biosynthetic process" EXACT [] synonym: "downregulation of interferon-alpha biosynthetic process" EXACT [] synonym: "inhibition of interferon-alpha biosynthetic process" NARROW [] synonym: "negative regulation of interferon-alpha anabolism" EXACT [] synonym: "negative regulation of interferon-alpha biosynthesis" EXACT [] synonym: "negative regulation of interferon-alpha formation" EXACT [] synonym: "negative regulation of interferon-alpha synthesis" EXACT [] xref: GO:0045355 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002295 ! regulation of interferon-alpha biosynthetic process relationship: has_participant CCO:B0055142 ! IL10_HUMAN [Term] id: CCO:P0002297 name: positive regulation of interferon-alpha biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha." [GOC:go_curators] synonym: "activation of interferon-alpha biosynthetic process" NARROW [] synonym: "positive regulation of interferon-alpha anabolism" EXACT [] synonym: "positive regulation of interferon-alpha biosynthesis" EXACT [] synonym: "positive regulation of interferon-alpha formation" EXACT [] synonym: "positive regulation of interferon-alpha synthesis" EXACT [] synonym: "stimulation of interferon-alpha biosynthetic process" NARROW [] synonym: "up regulation of interferon-alpha biosynthetic process" EXACT [] synonym: "up-regulation of interferon-alpha biosynthetic process" EXACT [] synonym: "upregulation of interferon-alpha biosynthetic process" EXACT [] xref: GO:0045356 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002295 ! regulation of interferon-alpha biosynthetic process relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0058891 ! TLR9_HUMAN relationship: has_participant CCO:B0058892 ! TLR8_HUMAN relationship: has_participant CCO:B0058964 ! TLR7_HUMAN [Term] id: CCO:P0002298 name: regulation of interferon-beta biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta." [GOC:go_curators] synonym: "regulation of interferon-beta anabolism" EXACT [] synonym: "regulation of interferon-beta biosynthesis" EXACT [] synonym: "regulation of interferon-beta formation" EXACT [] synonym: "regulation of interferon-beta synthesis" EXACT [] xref: GO:0045357 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002299 name: negative regulation of interferon-beta biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta." [GOC:go_curators] synonym: "down regulation of interferon-beta biosynthetic process" EXACT [] synonym: "down-regulation of interferon-beta biosynthetic process" EXACT [] synonym: "downregulation of interferon-beta biosynthetic process" EXACT [] synonym: "inhibition of interferon-beta biosynthetic process" NARROW [] synonym: "negative regulation of interferon-beta anabolism" EXACT [] synonym: "negative regulation of interferon-beta biosynthesis" EXACT [] synonym: "negative regulation of interferon-beta formation" EXACT [] synonym: "negative regulation of interferon-beta synthesis" EXACT [] xref: GO:0045358 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002298 ! regulation of interferon-beta biosynthetic process [Term] id: CCO:P0002300 name: positive regulation of interferon-beta biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta." [GOC:go_curators] synonym: "activation of interferon-beta biosynthetic process" NARROW [] synonym: "positive regulation of interferon-beta anabolism" EXACT [] synonym: "positive regulation of interferon-beta biosynthesis" EXACT [] synonym: "positive regulation of interferon-beta formation" EXACT [] synonym: "positive regulation of interferon-beta synthesis" EXACT [] synonym: "stimulation of interferon-beta biosynthetic process" NARROW [] synonym: "up regulation of interferon-beta biosynthetic process" EXACT [] synonym: "up-regulation of interferon-beta biosynthetic process" EXACT [] synonym: "upregulation of interferon-beta biosynthetic process" EXACT [] xref: GO:0045359 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002298 ! regulation of interferon-beta biosynthetic process relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0058891 ! TLR9_HUMAN relationship: has_participant CCO:B0058892 ! TLR8_HUMAN relationship: has_participant CCO:B0058964 ! TLR7_HUMAN [Term] id: CCO:P0002301 name: regulation of interleukin-1 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1." [GOC:go_curators] synonym: "regulation of IL-1 biosynthesis" EXACT [] synonym: "regulation of IL-1 biosynthetic process" EXACT [] synonym: "regulation of interleukin-1 anabolism" EXACT [] synonym: "regulation of interleukin-1 biosynthesis" EXACT [] synonym: "regulation of interleukin-1 formation" EXACT [] synonym: "regulation of interleukin-1 synthesis" EXACT [] xref: GO:0045360 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002302 name: negative regulation of interleukin-1 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1." [GOC:go_curators] synonym: "down regulation of interleukin-1 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-1 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-1 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-1 biosynthetic process" NARROW [] synonym: "negative regulation of IL-1 biosynthesis" EXACT [] synonym: "negative regulation of IL-1 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-1 anabolism" EXACT [] synonym: "negative regulation of interleukin-1 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-1 formation" EXACT [] synonym: "negative regulation of interleukin-1 synthesis" EXACT [] xref: GO:0045361 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002301 ! regulation of interleukin-1 biosynthetic process [Term] id: CCO:P0002303 name: positive regulation of interleukin-1 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1." [GOC:go_curators] synonym: "activation of interleukin-1 biosynthetic process" NARROW [] synonym: "positive regulation of IL-1 biosynthesis" EXACT [] synonym: "positive regulation of IL-1 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-1 anabolism" EXACT [] synonym: "positive regulation of interleukin-1 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-1 formation" EXACT [] synonym: "positive regulation of interleukin-1 synthesis" EXACT [] synonym: "stimulation of interleukin-1 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-1 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-1 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-1 biosynthetic process" EXACT [] xref: GO:0045362 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002301 ! regulation of interleukin-1 biosynthetic process [Term] id: CCO:P0002304 name: regulation of interleukin-11 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11." [GOC:go_curators] synonym: "regulation of IL-11 biosynthesis" EXACT [] synonym: "regulation of IL-11 biosynthetic process" EXACT [] synonym: "regulation of interleukin-11 anabolism" EXACT [] synonym: "regulation of interleukin-11 biosynthesis" EXACT [] synonym: "regulation of interleukin-11 formation" EXACT [] synonym: "regulation of interleukin-11 synthesis" EXACT [] xref: GO:0045363 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002305 name: negative regulation of interleukin-11 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11." [GOC:go_curators] synonym: "down regulation of interleukin-11 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-11 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-11 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-11 biosynthetic process" NARROW [] synonym: "negative regulation of IL-11 biosynthesis" EXACT [] synonym: "negative regulation of IL-11 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-11 anabolism" EXACT [] synonym: "negative regulation of interleukin-11 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-11 formation" EXACT [] synonym: "negative regulation of interleukin-11 synthesis" EXACT [] xref: GO:0045364 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002304 ! regulation of interleukin-11 biosynthetic process [Term] id: CCO:P0002306 name: positive regulation of interleukin-11 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11." [GOC:go_curators] synonym: "activation of interleukin-11 biosynthetic process" NARROW [] synonym: "positive regulation of IL-11 biosynthesis" EXACT [] synonym: "positive regulation of IL-11 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-11 anabolism" EXACT [] synonym: "positive regulation of interleukin-11 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-11 formation" EXACT [] synonym: "positive regulation of interleukin-11 synthesis" EXACT [] synonym: "stimulation of interleukin-11 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-11 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-11 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-11 biosynthetic process" EXACT [] xref: GO:0045365 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002304 ! regulation of interleukin-11 biosynthetic process [Term] id: CCO:P0002307 name: regulation of interleukin-13 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13." [GOC:go_curators] synonym: "regulation of IL-13 biosynthesis" EXACT [] synonym: "regulation of IL-13 biosynthetic process" EXACT [] synonym: "regulation of interleukin-13 anabolism" EXACT [] synonym: "regulation of interleukin-13 biosynthesis" EXACT [] synonym: "regulation of interleukin-13 formation" EXACT [] synonym: "regulation of interleukin-13 synthesis" EXACT [] xref: GO:0045366 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002308 name: negative regulation of interleukin-13 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13." [GOC:go_curators] synonym: "down regulation of interleukin-13 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-13 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-13 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-13 biosynthetic process" NARROW [] synonym: "negative regulation of IL-13 biosynthesis" EXACT [] synonym: "negative regulation of IL-13 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-13 anabolism" EXACT [] synonym: "negative regulation of interleukin-13 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-13 formation" EXACT [] synonym: "negative regulation of interleukin-13 synthesis" EXACT [] xref: GO:0045367 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002307 ! regulation of interleukin-13 biosynthetic process [Term] id: CCO:P0002309 name: positive regulation of interleukin-13 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13." [GOC:go_curators] synonym: "activation of interleukin-13 biosynthetic process" NARROW [] synonym: "positive regulation of IL-13 biosynthesis" EXACT [] synonym: "positive regulation of IL-13 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-13 anabolism" EXACT [] synonym: "positive regulation of interleukin-13 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-13 formation" EXACT [] synonym: "positive regulation of interleukin-13 synthesis" EXACT [] synonym: "stimulation of interleukin-13 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-13 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-13 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-13 biosynthetic process" EXACT [] xref: GO:0045368 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002307 ! regulation of interleukin-13 biosynthetic process relationship: has_participant CCO:B0056056 ! IRF4_HUMAN relationship: has_participant CCO:B0058411 ! Q99419_HUMAN [Term] id: CCO:P0002310 name: regulation of interleukin-14 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14." [GOC:go_curators] synonym: "regulation of IL-14 biosynthesis" EXACT [] synonym: "regulation of IL-14 biosynthetic process" EXACT [] synonym: "regulation of interleukin-14 anabolism" EXACT [] synonym: "regulation of interleukin-14 biosynthesis" EXACT [] synonym: "regulation of interleukin-14 formation" EXACT [] synonym: "regulation of interleukin-14 synthesis" EXACT [] xref: GO:0045369 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002311 name: negative regulation of interleukin-14 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14." [GOC:go_curators] synonym: "down regulation of interleukin-14 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-14 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-14 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-14 biosynthetic process" NARROW [] synonym: "negative regulation of IL-14 biosynthesis" EXACT [] synonym: "negative regulation of IL-14 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-14 anabolism" EXACT [] synonym: "negative regulation of interleukin-14 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-14 formation" EXACT [] synonym: "negative regulation of interleukin-14 synthesis" EXACT [] xref: GO:0045370 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002310 ! regulation of interleukin-14 biosynthetic process [Term] id: CCO:P0002312 name: positive regulation of interleukin-14 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14." [GOC:go_curators] synonym: "activation of interleukin-14 biosynthetic process" NARROW [] synonym: "positive regulation of IL-14 biosynthesis" EXACT [] synonym: "positive regulation of IL-14 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-14 anabolism" EXACT [] synonym: "positive regulation of interleukin-14 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-14 formation" EXACT [] synonym: "positive regulation of interleukin-14 synthesis" EXACT [] synonym: "stimulation of interleukin-14 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-14 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-14 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-14 biosynthetic process" EXACT [] xref: GO:0045371 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002310 ! regulation of interleukin-14 biosynthetic process [Term] id: CCO:P0002313 name: regulation of interleukin-15 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15." [GOC:go_curators] synonym: "regulation of IL-15 biosynthesis" EXACT [] synonym: "regulation of IL-15 biosynthetic process" EXACT [] synonym: "regulation of interleukin-15 anabolism" EXACT [] synonym: "regulation of interleukin-15 biosynthesis" EXACT [] synonym: "regulation of interleukin-15 formation" EXACT [] synonym: "regulation of interleukin-15 synthesis" EXACT [] xref: GO:0045372 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002314 name: negative regulation of interleukin-15 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15." [GOC:go_curators] synonym: "down regulation of interleukin-15 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-15 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-15 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-15 biosynthetic process" NARROW [] synonym: "negative regulation of IL-15 biosynthesis" EXACT [] synonym: "negative regulation of IL-15 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-15 anabolism" EXACT [] synonym: "negative regulation of interleukin-15 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-15 formation" EXACT [] synonym: "negative regulation of interleukin-15 synthesis" EXACT [] xref: GO:0045373 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002313 ! regulation of interleukin-15 biosynthetic process [Term] id: CCO:P0002315 name: positive regulation of interleukin-15 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15." [GOC:go_curators] synonym: "activation of interleukin-15 biosynthetic process" NARROW [] synonym: "positive regulation of IL-15 biosynthesis" EXACT [] synonym: "positive regulation of IL-15 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-15 anabolism" EXACT [] synonym: "positive regulation of interleukin-15 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-15 formation" EXACT [] synonym: "positive regulation of interleukin-15 synthesis" EXACT [] synonym: "stimulation of interleukin-15 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-15 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-15 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-15 biosynthetic process" EXACT [] xref: GO:0045374 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002313 ! regulation of interleukin-15 biosynthetic process [Term] id: CCO:P0002316 name: regulation of interleukin-16 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16." [GOC:go_curators] synonym: "regulation of IL-16 biosynthesis" EXACT [] synonym: "regulation of IL-16 biosynthetic process" EXACT [] synonym: "regulation of interleukin-16 anabolism" EXACT [] synonym: "regulation of interleukin-16 biosynthesis" EXACT [] synonym: "regulation of interleukin-16 formation" EXACT [] synonym: "regulation of interleukin-16 synthesis" EXACT [] xref: GO:0045375 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002317 name: negative regulation of interleukin-16 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16." [GOC:go_curators] synonym: "down regulation of interleukin-16 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-16 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-16 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-16 biosynthetic process" NARROW [] synonym: "negative regulation of IL-16 biosynthesis" EXACT [] synonym: "negative regulation of IL-16 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-16 anabolism" EXACT [] synonym: "negative regulation of interleukin-16 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-16 formation" EXACT [] synonym: "negative regulation of interleukin-16 synthesis" EXACT [] xref: GO:0045376 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002316 ! regulation of interleukin-16 biosynthetic process [Term] id: CCO:P0002318 name: positive regulation of interleukin-16 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16." [GOC:go_curators] synonym: "activation of interleukin-16 biosynthetic process" NARROW [] synonym: "positive regulation of IL-16 biosynthesis" EXACT [] synonym: "positive regulation of IL-16 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-16 anabolism" EXACT [] synonym: "positive regulation of interleukin-16 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-16 formation" EXACT [] synonym: "positive regulation of interleukin-16 synthesis" EXACT [] synonym: "stimulation of interleukin-16 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-16 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-16 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-16 biosynthetic process" EXACT [] xref: GO:0045377 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002316 ! regulation of interleukin-16 biosynthetic process [Term] id: CCO:P0002319 name: regulation of interleukin-17 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17." [GOC:go_curators] synonym: "regulation of IL-17 biosynthesis" EXACT [] synonym: "regulation of IL-17 biosynthetic process" EXACT [] synonym: "regulation of interleukin-17 anabolism" EXACT [] synonym: "regulation of interleukin-17 biosynthesis" EXACT [] synonym: "regulation of interleukin-17 formation" EXACT [] synonym: "regulation of interleukin-17 synthesis" EXACT [] xref: GO:0045378 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002320 name: negative regulation of interleukin-17 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17." [GOC:go_curators] synonym: "down regulation of interleukin-17 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-17 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-17 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-17 biosynthetic process" NARROW [] synonym: "negative regulation of IL-17 biosynthesis" EXACT [] synonym: "negative regulation of IL-17 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-17 anabolism" EXACT [] synonym: "negative regulation of interleukin-17 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-17 formation" EXACT [] synonym: "negative regulation of interleukin-17 synthesis" EXACT [] xref: GO:0045379 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002319 ! regulation of interleukin-17 biosynthetic process [Term] id: CCO:P0002321 name: positive regulation of interleukin-17 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17." [GOC:go_curators] synonym: "activation of interleukin-17 biosynthetic process" NARROW [] synonym: "positive regulation of IL-17 biosynthesis" EXACT [] synonym: "positive regulation of IL-17 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-17 anabolism" EXACT [] synonym: "positive regulation of interleukin-17 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-17 formation" EXACT [] synonym: "positive regulation of interleukin-17 synthesis" EXACT [] synonym: "stimulation of interleukin-17 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-17 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-17 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-17 biosynthetic process" EXACT [] xref: GO:0045380 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002319 ! regulation of interleukin-17 biosynthetic process [Term] id: CCO:P0002322 name: regulation of interleukin-18 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18." [GOC:go_curators] synonym: "regulation of IL-18 biosynthesis" EXACT [] synonym: "regulation of IL-18 biosynthetic process" EXACT [] synonym: "regulation of interleukin-18 anabolism" EXACT [] synonym: "regulation of interleukin-18 biosynthesis" EXACT [] synonym: "regulation of interleukin-18 formation" EXACT [] synonym: "regulation of interleukin-18 synthesis" EXACT [] xref: GO:0045381 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: has_participant CCO:B0055574 ! NAL12_HUMAN [Term] id: CCO:P0002323 name: negative regulation of interleukin-18 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18." [GOC:go_curators] synonym: "down regulation of interleukin-18 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-18 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-18 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-18 biosynthetic process" NARROW [] synonym: "negative regulation of IL-18 biosynthesis" EXACT [] synonym: "negative regulation of IL-18 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-18 anabolism" EXACT [] synonym: "negative regulation of interleukin-18 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-18 formation" EXACT [] synonym: "negative regulation of interleukin-18 synthesis" EXACT [] xref: GO:0045382 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002322 ! regulation of interleukin-18 biosynthetic process [Term] id: CCO:P0002324 name: positive regulation of interleukin-18 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18." [GOC:go_curators] synonym: "activation of interleukin-18 biosynthetic process" NARROW [] synonym: "positive regulation of IL-18 biosynthesis" EXACT [] synonym: "positive regulation of IL-18 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-18 anabolism" EXACT [] synonym: "positive regulation of interleukin-18 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-18 formation" EXACT [] synonym: "positive regulation of interleukin-18 synthesis" EXACT [] synonym: "stimulation of interleukin-18 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-18 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-18 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-18 biosynthetic process" EXACT [] xref: GO:0045383 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002322 ! regulation of interleukin-18 biosynthetic process [Term] id: CCO:P0002325 name: regulation of interleukin-19 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19." [GOC:go_curators] synonym: "regulation of IL-19 biosynthesis" EXACT [] synonym: "regulation of IL-19 biosynthetic process" EXACT [] synonym: "regulation of interleukin-19 anabolism" EXACT [] synonym: "regulation of interleukin-19 biosynthesis" EXACT [] synonym: "regulation of interleukin-19 formation" EXACT [] synonym: "regulation of interleukin-19 synthesis" EXACT [] xref: GO:0045384 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002326 name: negative regulation of interleukin-19 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19." [GOC:go_curators] synonym: "down regulation of interleukin-19 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-19 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-19 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-19 biosynthetic process" NARROW [] synonym: "negative regulation of IL-19 biosynthesis" EXACT [] synonym: "negative regulation of IL-19 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-19 anabolism" EXACT [] synonym: "negative regulation of interleukin-19 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-19 formation" EXACT [] synonym: "negative regulation of interleukin-19 synthesis" EXACT [] xref: GO:0045385 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002325 ! regulation of interleukin-19 biosynthetic process [Term] id: CCO:P0002327 name: positive regulation of interleukin-19 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19." [GOC:go_curators] synonym: "activation of interleukin-19 biosynthetic process" NARROW [] synonym: "positive regulation of IL-19 biosynthesis" EXACT [] synonym: "positive regulation of IL-19 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-19 anabolism" EXACT [] synonym: "positive regulation of interleukin-19 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-19 formation" EXACT [] synonym: "positive regulation of interleukin-19 synthesis" EXACT [] synonym: "stimulation of interleukin-19 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-19 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-19 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-19 biosynthetic process" EXACT [] xref: GO:0045386 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002325 ! regulation of interleukin-19 biosynthetic process [Term] id: CCO:P0002328 name: regulation of interleukin-20 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20." [GOC:go_curators] synonym: "regulation of IL-20 biosynthesis" EXACT [] synonym: "regulation of IL-20 biosynthetic process" EXACT [] synonym: "regulation of interleukin-20 anabolism" EXACT [] synonym: "regulation of interleukin-20 biosynthesis" EXACT [] synonym: "regulation of interleukin-20 formation" EXACT [] synonym: "regulation of interleukin-20 synthesis" EXACT [] xref: GO:0045387 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002329 name: negative regulation of interleukin-20 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20." [GOC:go_curators] synonym: "down regulation of interleukin-20 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-20 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-20 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-20 biosynthetic process" NARROW [] synonym: "negative regulation of IL-20 biosynthesis" EXACT [] synonym: "negative regulation of IL-20 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-20 anabolism" EXACT [] synonym: "negative regulation of interleukin-20 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-20 formation" EXACT [] synonym: "negative regulation of interleukin-20 synthesis" EXACT [] xref: GO:0045388 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002328 ! regulation of interleukin-20 biosynthetic process [Term] id: CCO:P0002330 name: positive regulation of interleukin-20 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20." [GOC:go_curators] synonym: "activation of interleukin-20 biosynthetic process" NARROW [] synonym: "positive regulation of IL-20 biosynthesis" EXACT [] synonym: "positive regulation of IL-20 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-20 anabolism" EXACT [] synonym: "positive regulation of interleukin-20 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-20 formation" EXACT [] synonym: "positive regulation of interleukin-20 synthesis" EXACT [] synonym: "stimulation of interleukin-20 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-20 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-20 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-20 biosynthetic process" EXACT [] xref: GO:0045389 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002328 ! regulation of interleukin-20 biosynthetic process [Term] id: CCO:P0002331 name: regulation of interleukin-21 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21." [GOC:go_curators] synonym: "regulation of IL-21 biosynthesis" EXACT [] synonym: "regulation of IL-21 biosynthetic process" EXACT [] synonym: "regulation of interleukin-21 anabolism" EXACT [] synonym: "regulation of interleukin-21 biosynthesis" EXACT [] synonym: "regulation of interleukin-21 formation" EXACT [] synonym: "regulation of interleukin-21 synthesis" EXACT [] xref: GO:0045390 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002332 name: negative regulation of interleukin-21 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21." [GOC:go_curators] synonym: "down regulation of interleukin-21 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-21 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-21 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-21 biosynthetic process" NARROW [] synonym: "negative regulation of IL-21 biosynthesis" EXACT [] synonym: "negative regulation of IL-21 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-21 anabolism" EXACT [] synonym: "negative regulation of interleukin-21 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-21 formation" EXACT [] synonym: "negative regulation of interleukin-21 synthesis" EXACT [] xref: GO:0045391 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002331 ! regulation of interleukin-21 biosynthetic process [Term] id: CCO:P0002333 name: positive regulation of interleukin-21 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21." [GOC:go_curators] synonym: "activation of interleukin-21 biosynthetic process" NARROW [] synonym: "positive regulation of IL-21 biosynthesis" EXACT [] synonym: "positive regulation of IL-21 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-21 anabolism" EXACT [] synonym: "positive regulation of interleukin-21 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-21 formation" EXACT [] synonym: "positive regulation of interleukin-21 synthesis" EXACT [] synonym: "stimulation of interleukin-21 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-21 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-21 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-21 biosynthetic process" EXACT [] xref: GO:0045392 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002331 ! regulation of interleukin-21 biosynthetic process [Term] id: CCO:P0002334 name: regulation of interleukin-22 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22." [GOC:go_curators] synonym: "regulation of IL-22 biosynthesis" EXACT [] synonym: "regulation of IL-22 biosynthetic process" EXACT [] synonym: "regulation of interleukin-22 anabolism" EXACT [] synonym: "regulation of interleukin-22 biosynthesis" EXACT [] synonym: "regulation of interleukin-22 formation" EXACT [] synonym: "regulation of interleukin-22 synthesis" EXACT [] xref: GO:0045393 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002335 name: negative regulation of interleukin-22 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22." [GOC:go_curators] synonym: "down regulation of interleukin-22 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-22 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-22 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-22 biosynthetic process" NARROW [] synonym: "negative regulation of IL-22 biosynthesis" EXACT [] synonym: "negative regulation of IL-22 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-22 anabolism" EXACT [] synonym: "negative regulation of interleukin-22 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-22 formation" EXACT [] synonym: "negative regulation of interleukin-22 synthesis" EXACT [] xref: GO:0045394 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002334 ! regulation of interleukin-22 biosynthetic process [Term] id: CCO:P0002336 name: positive regulation of interleukin-22 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22." [GOC:go_curators] synonym: "activation of interleukin-22 biosynthetic process" NARROW [] synonym: "positive regulation of IL-22 biosynthesis" EXACT [] synonym: "positive regulation of IL-22 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-22 anabolism" EXACT [] synonym: "positive regulation of interleukin-22 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-22 formation" EXACT [] synonym: "positive regulation of interleukin-22 synthesis" EXACT [] synonym: "stimulation of interleukin-22 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-22 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-22 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-22 biosynthetic process" EXACT [] xref: GO:0045395 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002334 ! regulation of interleukin-22 biosynthetic process [Term] id: CCO:P0002337 name: regulation of interleukin-23 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23." [GOC:go_curators] synonym: "regulation of IL-23 biosynthesis" EXACT [] synonym: "regulation of IL-23 biosynthetic process" EXACT [] synonym: "regulation of interleukin-23 anabolism" EXACT [] synonym: "regulation of interleukin-23 biosynthesis" EXACT [] synonym: "regulation of interleukin-23 formation" EXACT [] synonym: "regulation of interleukin-23 synthesis" EXACT [] xref: GO:0045396 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002338 name: negative regulation of interleukin-23 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23." [GOC:go_curators] synonym: "down regulation of interleukin-23 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-23 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-23 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-23 biosynthetic process" NARROW [] synonym: "negative regulation of IL-23 biosynthesis" EXACT [] synonym: "negative regulation of IL-23 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-23 anabolism" EXACT [] synonym: "negative regulation of interleukin-23 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-23 formation" EXACT [] synonym: "negative regulation of interleukin-23 synthesis" EXACT [] xref: GO:0045397 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002337 ! regulation of interleukin-23 biosynthetic process [Term] id: CCO:P0002339 name: positive regulation of interleukin-23 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23." [GOC:go_curators] synonym: "activation of interleukin-23 biosynthetic process" NARROW [] synonym: "positive regulation of IL-23 biosynthesis" EXACT [] synonym: "positive regulation of IL-23 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-23 anabolism" EXACT [] synonym: "positive regulation of interleukin-23 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-23 formation" EXACT [] synonym: "positive regulation of interleukin-23 synthesis" EXACT [] synonym: "stimulation of interleukin-23 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-23 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-23 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-23 biosynthetic process" EXACT [] xref: GO:0045398 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002337 ! regulation of interleukin-23 biosynthetic process [Term] id: CCO:P0002340 name: regulation of interleukin-3 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3." [GOC:go_curators] synonym: "regulation of IL-3 biosynthesis" EXACT [] synonym: "regulation of IL-3 biosynthetic process" EXACT [] synonym: "regulation of interleukin-3 anabolism" EXACT [] synonym: "regulation of interleukin-3 biosynthesis" EXACT [] synonym: "regulation of interleukin-3 formation" EXACT [] synonym: "regulation of interleukin-3 synthesis" EXACT [] xref: GO:0045399 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002341 name: negative regulation of interleukin-3 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3." [GOC:go_curators] synonym: "down regulation of interleukin-3 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-3 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-3 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-3 biosynthetic process" NARROW [] synonym: "negative regulation of IL-3 biosynthesis" EXACT [] synonym: "negative regulation of IL-3 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-3 anabolism" EXACT [] synonym: "negative regulation of interleukin-3 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-3 formation" EXACT [] synonym: "negative regulation of interleukin-3 synthesis" EXACT [] xref: GO:0045400 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002340 ! regulation of interleukin-3 biosynthetic process [Term] id: CCO:P0002342 name: positive regulation of interleukin-3 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3." [GOC:go_curators] synonym: "activation of interleukin-3 biosynthetic process" NARROW [] synonym: "positive regulation of IL-3 biosynthesis" EXACT [] synonym: "positive regulation of IL-3 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-3 anabolism" EXACT [] synonym: "positive regulation of interleukin-3 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-3 formation" EXACT [] synonym: "positive regulation of interleukin-3 synthesis" EXACT [] synonym: "stimulation of interleukin-3 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-3 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-3 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-3 biosynthetic process" EXACT [] xref: GO:0045401 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002340 ! regulation of interleukin-3 biosynthetic process relationship: has_participant CCO:B0042830 ! FCERA_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:P0002343 name: regulation of interleukin-4 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4." [GOC:go_curators] synonym: "regulation of IL-4 biosynthesis" EXACT [] synonym: "regulation of IL-4 biosynthetic process" EXACT [] synonym: "regulation of interleukin-4 anabolism" EXACT [] synonym: "regulation of interleukin-4 biosynthesis" EXACT [] synonym: "regulation of interleukin-4 formation" EXACT [] synonym: "regulation of interleukin-4 synthesis" EXACT [] xref: GO:0045402 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002344 name: negative regulation of interleukin-4 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4." [GOC:go_curators] synonym: "down regulation of interleukin-4 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-4 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-4 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-4 biosynthetic process" NARROW [] synonym: "negative regulation of IL-4 biosynthesis" EXACT [] synonym: "negative regulation of IL-4 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-4 anabolism" EXACT [] synonym: "negative regulation of interleukin-4 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-4 formation" EXACT [] synonym: "negative regulation of interleukin-4 synthesis" EXACT [] xref: GO:0045403 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002343 ! regulation of interleukin-4 biosynthetic process [Term] id: CCO:P0002345 name: positive regulation of interleukin-4 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4." [GOC:go_curators] synonym: "activation of interleukin-4 biosynthetic process" NARROW [] synonym: "positive regulation of IL-4 biosynthesis" EXACT [] synonym: "positive regulation of IL-4 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-4 anabolism" EXACT [] synonym: "positive regulation of interleukin-4 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-4 formation" EXACT [] synonym: "positive regulation of interleukin-4 synthesis" EXACT [] synonym: "stimulation of interleukin-4 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-4 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-4 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-4 biosynthetic process" EXACT [] xref: GO:0045404 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002343 ! regulation of interleukin-4 biosynthetic process relationship: has_participant CCO:B0055346 ! CD86_HUMAN relationship: has_participant CCO:B0056056 ! IRF4_HUMAN relationship: has_participant CCO:B0058411 ! Q99419_HUMAN [Term] id: CCO:P0002346 name: regulation of interleukin-5 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5." [GOC:go_curators] synonym: "regulation of IL-5 biosynthesis" EXACT [] synonym: "regulation of IL-5 biosynthetic process" EXACT [] synonym: "regulation of interleukin-5 anabolism" EXACT [] synonym: "regulation of interleukin-5 biosynthesis" EXACT [] synonym: "regulation of interleukin-5 formation" EXACT [] synonym: "regulation of interleukin-5 synthesis" EXACT [] xref: GO:0045405 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002347 name: negative regulation of interleukin-5 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5." [GOC:go_curators] synonym: "down regulation of interleukin-5 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-5 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-5 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-5 biosynthetic process" NARROW [] synonym: "negative regulation of IL-5 biosynthesis" EXACT [] synonym: "negative regulation of IL-5 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-5 anabolism" EXACT [] synonym: "negative regulation of interleukin-5 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-5 formation" EXACT [] synonym: "negative regulation of interleukin-5 synthesis" EXACT [] xref: GO:0045406 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002346 ! regulation of interleukin-5 biosynthetic process [Term] id: CCO:P0002348 name: positive regulation of interleukin-5 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5." [GOC:go_curators] synonym: "activation of interleukin-5 biosynthetic process" NARROW [] synonym: "positive regulation of IL-5 biosynthesis" EXACT [] synonym: "positive regulation of IL-5 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-5 anabolism" EXACT [] synonym: "positive regulation of interleukin-5 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-5 formation" EXACT [] synonym: "positive regulation of interleukin-5 synthesis" EXACT [] synonym: "stimulation of interleukin-5 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-5 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-5 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-5 biosynthetic process" EXACT [] xref: GO:0045407 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002346 ! regulation of interleukin-5 biosynthetic process relationship: has_participant CCO:B0055032 ! IL9_HUMAN [Term] id: CCO:P0002349 name: regulation of interleukin-6 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6." [GOC:go_curators] synonym: "regulation of IL-6 biosynthesis" EXACT [] synonym: "regulation of IL-6 biosynthetic process" EXACT [] synonym: "regulation of interleukin-6 anabolism" EXACT [] synonym: "regulation of interleukin-6 biosynthesis" EXACT [] synonym: "regulation of interleukin-6 formation" EXACT [] synonym: "regulation of interleukin-6 synthesis" EXACT [] xref: GO:0045408 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN [Term] id: CCO:P0002350 name: negative regulation of interleukin-6 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6." [GOC:go_curators] synonym: "down regulation of interleukin-6 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-6 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-6 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-6 biosynthetic process" NARROW [] synonym: "negative regulation of IL-6 biosynthesis" EXACT [] synonym: "negative regulation of IL-6 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-6 anabolism" EXACT [] synonym: "negative regulation of interleukin-6 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-6 formation" EXACT [] synonym: "negative regulation of interleukin-6 synthesis" EXACT [] xref: GO:0045409 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002349 ! regulation of interleukin-6 biosynthetic process relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0039142 ! FOXJ1_HUMAN relationship: has_participant CCO:B0055574 ! NAL12_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN [Term] id: CCO:P0002351 name: positive regulation of interleukin-6 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6." [GOC:go_curators] synonym: "activation of interleukin-6 biosynthetic process" NARROW [] synonym: "positive regulation of IL-6 biosynthesis" EXACT [] synonym: "positive regulation of IL-6 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-6 anabolism" EXACT [] synonym: "positive regulation of interleukin-6 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-6 formation" EXACT [] synonym: "positive regulation of interleukin-6 synthesis" EXACT [] synonym: "stimulation of interleukin-6 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-6 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-6 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-6 biosynthetic process" EXACT [] xref: GO:0045410 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002349 ! regulation of interleukin-6 biosynthetic process relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0030164 ! TLR1_HUMAN relationship: has_participant CCO:B0030172 ! TLR6_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN [Term] id: CCO:P0002352 name: regulation of interleukin-7 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7." [GOC:go_curators] synonym: "regulation of IL-7 biosynthesis" EXACT [] synonym: "regulation of IL-7 biosynthetic process" EXACT [] synonym: "regulation of interleukin-7 anabolism" EXACT [] synonym: "regulation of interleukin-7 biosynthesis" EXACT [] synonym: "regulation of interleukin-7 formation" EXACT [] synonym: "regulation of interleukin-7 synthesis" EXACT [] xref: GO:0045411 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002353 name: negative regulation of interleukin-7 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7." [GOC:go_curators] synonym: "down regulation of interleukin-7 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-7 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-7 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-7 biosynthetic process" NARROW [] synonym: "negative regulation of IL-7 biosynthesis" EXACT [] synonym: "negative regulation of IL-7 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-7 anabolism" EXACT [] synonym: "negative regulation of interleukin-7 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-7 formation" EXACT [] synonym: "negative regulation of interleukin-7 synthesis" EXACT [] xref: GO:0045412 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002352 ! regulation of interleukin-7 biosynthetic process [Term] id: CCO:P0002354 name: positive regulation of interleukin-7 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7." [GOC:go_curators] synonym: "activation of interleukin-7 biosynthetic process" NARROW [] synonym: "positive regulation of IL-7 biosynthesis" EXACT [] synonym: "positive regulation of IL-7 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-7 anabolism" EXACT [] synonym: "positive regulation of interleukin-7 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-7 formation" EXACT [] synonym: "positive regulation of interleukin-7 synthesis" EXACT [] synonym: "stimulation of interleukin-7 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-7 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-7 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-7 biosynthetic process" EXACT [] xref: GO:0045413 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002352 ! regulation of interleukin-7 biosynthetic process [Term] id: CCO:P0002355 name: regulation of interleukin-8 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8." [GOC:go_curators] synonym: "regulation of IL-8 biosynthesis" EXACT [] synonym: "regulation of IL-8 biosynthetic process" EXACT [] synonym: "regulation of interleukin-8 anabolism" EXACT [] synonym: "regulation of interleukin-8 biosynthesis" EXACT [] synonym: "regulation of interleukin-8 formation" EXACT [] synonym: "regulation of interleukin-8 synthesis" EXACT [] xref: GO:0045414 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002356 name: negative regulation of interleukin-8 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8." [GOC:go_curators] synonym: "down regulation of interleukin-8 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-8 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-8 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-8 biosynthetic process" NARROW [] synonym: "negative regulation of IL-8 biosynthesis" EXACT [] synonym: "negative regulation of IL-8 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-8 anabolism" EXACT [] synonym: "negative regulation of interleukin-8 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-8 formation" EXACT [] synonym: "negative regulation of interleukin-8 synthesis" EXACT [] xref: GO:0045415 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002355 ! regulation of interleukin-8 biosynthetic process relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0054926 ! ELNE_HUMAN [Term] id: CCO:P0002357 name: positive regulation of interleukin-8 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8." [GOC:go_curators] synonym: "activation of interleukin-8 biosynthetic process" NARROW [] synonym: "positive regulation of IL-8 biosynthesis" EXACT [] synonym: "positive regulation of IL-8 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-8 anabolism" EXACT [] synonym: "positive regulation of interleukin-8 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-8 formation" EXACT [] synonym: "positive regulation of interleukin-8 synthesis" EXACT [] synonym: "stimulation of interleukin-8 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-8 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-8 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-8 biosynthetic process" EXACT [] xref: GO:0045416 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002355 ! regulation of interleukin-8 biosynthetic process relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0022071 ! TLR4_HUMAN relationship: has_participant CCO:B0054863 ! APOA2_HUMAN relationship: has_participant CCO:B0054926 ! ELNE_HUMAN relationship: has_participant CCO:B0058892 ! TLR8_HUMAN relationship: has_participant CCO:B0058964 ! TLR7_HUMAN relationship: has_participant CCO:B0059325 ! PRG3_HUMAN [Term] id: CCO:P0002358 name: regulation of interleukin-9 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9." [GOC:go_curators] synonym: "regulation of IL-9 biosynthesis" EXACT [] synonym: "regulation of IL-9 biosynthetic process" EXACT [] synonym: "regulation of interleukin-9 anabolism" EXACT [] synonym: "regulation of interleukin-9 biosynthesis" EXACT [] synonym: "regulation of interleukin-9 formation" EXACT [] synonym: "regulation of interleukin-9 synthesis" EXACT [] xref: GO:0045417 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002359 name: negative regulation of interleukin-9 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9." [GOC:go_curators] synonym: "down regulation of interleukin-9 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-9 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-9 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-9 biosynthetic process" NARROW [] synonym: "negative regulation of IL-9 biosynthesis" EXACT [] synonym: "negative regulation of IL-9 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-9 anabolism" EXACT [] synonym: "negative regulation of interleukin-9 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-9 formation" EXACT [] synonym: "negative regulation of interleukin-9 synthesis" EXACT [] xref: GO:0045418 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002358 ! regulation of interleukin-9 biosynthetic process [Term] id: CCO:P0002360 name: positive regulation of interleukin-9 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9." [GOC:go_curators] synonym: "activation of interleukin-9 biosynthetic process" NARROW [] synonym: "positive regulation of IL-9 biosynthesis" EXACT [] synonym: "positive regulation of IL-9 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-9 anabolism" EXACT [] synonym: "positive regulation of interleukin-9 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-9 formation" EXACT [] synonym: "positive regulation of interleukin-9 synthesis" EXACT [] synonym: "stimulation of interleukin-9 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-9 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-9 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-9 biosynthetic process" EXACT [] xref: GO:0045419 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002358 ! regulation of interleukin-9 biosynthetic process [Term] id: CCO:P0002361 name: regulation of connective tissue growth factor biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor." [GOC:go_curators] synonym: "regulation of connective tissue growth factor anabolism" EXACT [] synonym: "regulation of connective tissue growth factor biosynthesis" EXACT [] synonym: "regulation of connective tissue growth factor formation" EXACT [] synonym: "regulation of connective tissue growth factor synthesis" EXACT [] xref: GO:0045420 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002362 name: negative regulation of connective tissue growth factor biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor." [GOC:go_curators] synonym: "down regulation of connective tissue growth factor biosynthetic process" EXACT [] synonym: "down-regulation of connective tissue growth factor biosynthetic process" EXACT [] synonym: "downregulation of connective tissue growth factor biosynthetic process" EXACT [] synonym: "inhibition of connective tissue growth factor biosynthetic process" NARROW [] synonym: "negative regulation of connective tissue growth factor anabolism" EXACT [] synonym: "negative regulation of connective tissue growth factor biosynthesis" EXACT [] synonym: "negative regulation of connective tissue growth factor formation" EXACT [] synonym: "negative regulation of connective tissue growth factor synthesis" EXACT [] xref: GO:0045421 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002361 ! regulation of connective tissue growth factor biosynthetic process [Term] id: CCO:P0002363 name: positive regulation of connective tissue growth factor biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor." [GOC:go_curators] synonym: "activation of connective tissue growth factor biosynthetic process" NARROW [] synonym: "positive regulation of connective tissue growth factor anabolism" EXACT [] synonym: "positive regulation of connective tissue growth factor biosynthesis" EXACT [] synonym: "positive regulation of connective tissue growth factor formation" EXACT [] synonym: "positive regulation of connective tissue growth factor synthesis" EXACT [] synonym: "stimulation of connective tissue growth factor biosynthetic process" NARROW [] synonym: "up regulation of connective tissue growth factor biosynthetic process" EXACT [] synonym: "up-regulation of connective tissue growth factor biosynthetic process" EXACT [] synonym: "upregulation of connective tissue growth factor biosynthetic process" EXACT [] xref: GO:0045422 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002361 ! regulation of connective tissue growth factor biosynthetic process [Term] id: CCO:P0002364 name: regulation of granulocyte macrophage colony-stimulating factor biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor." [GOC:go_curators] synonym: "regulation of granulocyte macrophage colony-stimulating factor anabolism" EXACT [] synonym: "regulation of granulocyte macrophage colony-stimulating factor biosynthesis" EXACT [] synonym: "regulation of granulocyte macrophage colony-stimulating factor formation" EXACT [] synonym: "regulation of granulocyte macrophage colony-stimulating factor synthesis" EXACT [] xref: GO:0045423 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002365 name: negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor." [GOC:go_curators] synonym: "down regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] synonym: "down-regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] synonym: "downregulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] synonym: "inhibition of granulocyte macrophage colony-stimulating factor biosynthetic process" NARROW [] synonym: "negative regulation of granulocyte macrophage colony-stimulating factor anabolism" EXACT [] synonym: "negative regulation of granulocyte macrophage colony-stimulating factor biosynthesis" EXACT [] synonym: "negative regulation of granulocyte macrophage colony-stimulating factor formation" EXACT [] synonym: "negative regulation of granulocyte macrophage colony-stimulating factor synthesis" EXACT [] xref: GO:0045424 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002364 ! regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [Term] id: CCO:P0002366 name: positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor." [GOC:go_curators] synonym: "activation of granulocyte macrophage colony-stimulating factor biosynthetic process" NARROW [] synonym: "positive regulation of granulocyte macrophage colony-stimulating factor anabolism" EXACT [] synonym: "positive regulation of granulocyte macrophage colony-stimulating factor biosynthesis" EXACT [] synonym: "positive regulation of granulocyte macrophage colony-stimulating factor formation" EXACT [] synonym: "positive regulation of granulocyte macrophage colony-stimulating factor synthesis" EXACT [] synonym: "stimulation of granulocyte macrophage colony-stimulating factor biosynthetic process" NARROW [] synonym: "up regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] synonym: "up-regulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] synonym: "upregulation of granulocyte macrophage colony-stimulating factor biosynthetic process" EXACT [] xref: GO:0045425 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002364 ! regulation of granulocyte macrophage colony-stimulating factor biosynthetic process relationship: has_participant CCO:B0042830 ! FCERA_HUMAN relationship: has_participant CCO:B0055268 ! CD80_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:P0002367 name: regulation of nitric oxide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] synonym: "regulation of nitric oxide anabolism" EXACT [] synonym: "regulation of nitric oxide biosynthesis" EXACT [] synonym: "regulation of nitric oxide formation" EXACT [] synonym: "regulation of nitric oxide synthesis" EXACT [] xref: GO:0045428 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process relationship: has_participant CCO:B0055648 ! ARGI2_HUMAN [Term] id: CCO:P0002368 name: positive regulation of nitric oxide biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." [GOC:go_curators] synonym: "activation of nitric oxide biosynthetic process" NARROW [] synonym: "positive regulation of nitric oxide anabolism" EXACT [] synonym: "positive regulation of nitric oxide biosynthesis" EXACT [] synonym: "positive regulation of nitric oxide formation" EXACT [] synonym: "positive regulation of nitric oxide synthesis" EXACT [] synonym: "stimulation of nitric oxide biosynthetic process" NARROW [] synonym: "up regulation of nitric oxide biosynthetic process" EXACT [] synonym: "up-regulation of nitric oxide biosynthetic process" EXACT [] synonym: "upregulation of nitric oxide biosynthetic process" EXACT [] xref: GO:0045429 is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0002367 ! regulation of nitric oxide biosynthetic process relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005580 ! HS90B_HUMAN relationship: has_participant CCO:B0005698 ! HS90A_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN relationship: has_participant CCO:B0055190 ! PTX3_HUMAN relationship: has_participant CCO:B0055192 ! NKG2D_HUMAN relationship: has_participant CCO:B0055287 ! HRH1_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: has_participant CCO:B0055635 ! HBB_HUMAN relationship: has_participant CCO:B0058423 ! P2RX4_HUMAN [Term] id: CCO:P0002369 name: regulation of transcription namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"] subset: gosubset_prok xref: GO:0045449 is_a: CCO:P0000947 ! regulation of gene expression is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process relationship: has_participant CCO:B0001344 ! APBB1_HUMAN relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0001465 ! MYC_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001487 ! JUN_HUMAN relationship: has_participant CCO:B0001505 ! MYBB_HUMAN relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0001530 ! JUNB_HUMAN relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001591 ! PHB_HUMAN relationship: has_participant CCO:B0001595 ! AHR_HUMAN relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0001608 ! STAT1_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001643 ! DYN2_HUMAN relationship: has_participant CCO:B0001650 ! HCFC1_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0001717 ! ID3_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0001810 ! TERF2_HUMAN relationship: has_participant CCO:B0001831 ! Q3LRW5_HUMAN relationship: has_participant CCO:B0001998 ! Q8TEY4_HUMAN relationship: has_participant CCO:B0002020 ! APBB2_HUMAN relationship: has_participant CCO:B0002022 ! NGN1_HUMAN relationship: has_participant CCO:B0002065 ! CDC5L_HUMAN relationship: has_participant CCO:B0002074 ! MNT_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005274 ! RHXF2_HUMAN relationship: has_participant CCO:B0005318 ! Q9BVJ0_HUMAN relationship: has_participant CCO:B0005319 ! PDLI1_HUMAN relationship: has_participant CCO:B0005336 ! MAX_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005340 ! PAX5_HUMAN relationship: has_participant CCO:B0005360 ! MRGBP_HUMAN relationship: has_participant CCO:B0005361 ! VPS72_HUMAN relationship: has_participant CCO:B0005379 ! STAT3_HUMAN relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005431 ! CENPB_HUMAN relationship: has_participant CCO:B0005451 ! HXC10_HUMAN relationship: has_participant CCO:B0005498 ! CREB3_HUMAN relationship: has_participant CCO:B0005505 ! TE2IP_HUMAN relationship: has_participant CCO:B0005511 ! TLE1_HUMAN relationship: has_participant CCO:B0005527 ! NFKB2_HUMAN relationship: has_participant CCO:B0005529 ! RELB_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0005553 ! NCOR2_HUMAN relationship: has_participant CCO:B0005622 ! RPA12_HUMAN relationship: has_participant CCO:B0005623 ! MEOX2_HUMAN relationship: has_participant CCO:B0005632 ! MYB_HUMAN relationship: has_participant CCO:B0005657 ! TLE2_HUMAN relationship: has_participant CCO:B0005690 ! TLE3_HUMAN relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0005784 ! MED31_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN relationship: has_participant CCO:B0005895 ! PBX2_HUMAN relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0006030 ! COE1_HUMAN relationship: has_participant CCO:B0006033 ! ARNT2_HUMAN relationship: has_participant CCO:B0006042 ! MINT_HUMAN relationship: has_participant CCO:B0006049 ! PO2F3_HUMAN relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0006069 ! PO2F1_HUMAN relationship: has_participant CCO:B0006077 ! EPAS1_HUMAN relationship: has_participant CCO:B0006082 ! CHD3_HUMAN relationship: has_participant CCO:B0006121 ! ATF3_HUMAN relationship: has_participant CCO:B0006149 ! ID2_HUMAN relationship: has_participant CCO:B0006209 ! MYCBP_HUMAN relationship: has_participant CCO:B0006243 ! RFX1_HUMAN relationship: has_participant CCO:B0006246 ! TGIF1_HUMAN relationship: has_participant CCO:B0006303 ! TCEA2_HUMAN relationship: has_participant CCO:B0006341 ! PO3F3_HUMAN relationship: has_participant CCO:B0015243 ! TCEA3_HUMAN relationship: has_participant CCO:B0015397 ! Q9H7H9_HUMAN relationship: has_participant CCO:B0015398 ! MXI1_HUMAN relationship: has_participant CCO:B0015399 ! MAD4_HUMAN relationship: has_participant CCO:B0015400 ! MAD1_HUMAN relationship: has_participant CCO:B0015956 ! IFNK_HUMAN relationship: has_participant CCO:B0016028 ! HIRA_HUMAN relationship: has_participant CCO:B0016909 ! A6NFH2_HUMAN relationship: has_participant CCO:B0016914 ! Q9Y6S1_HUMAN relationship: has_participant CCO:B0016921 ! A6NFJ3_HUMAN relationship: has_participant CCO:B0016924 ! TLE4_HUMAN relationship: has_participant CCO:B0016926 ! A6NIY7_HUMAN relationship: has_participant CCO:B0018285 ! TF2H2_HUMAN relationship: has_participant CCO:B0018662 ! Q8IW86_HUMAN relationship: has_participant CCO:B0018664 ! TBX22_HUMAN relationship: has_participant CCO:B0018665 ! Q9HA44_HUMAN relationship: has_participant CCO:B0018667 ! Q5JT54_HUMAN relationship: has_participant CCO:B0018668 ! TBX1_HUMAN relationship: has_participant CCO:B0018669 ! TBX15_HUMAN relationship: has_participant CCO:B0018670 ! TBX6_HUMAN relationship: has_participant CCO:B0018671 ! Q5JZ06_HUMAN relationship: has_participant CCO:B0018672 ! Q000T4_HUMAN relationship: has_participant CCO:B0018676 ! TBX10_HUMAN relationship: has_participant CCO:B0018677 ! TBX18_HUMAN relationship: has_participant CCO:B0018678 ! TBX20_HUMAN relationship: has_participant CCO:B0019363 ! TAF5L_HUMAN relationship: has_participant CCO:B0019365 ! TAF5_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0020370 ! TGFR1_HUMAN relationship: has_participant CCO:B0021241 ! TF2LX_HUMAN relationship: has_participant CCO:B0021248 ! Q3ZCM9_HUMAN relationship: has_participant CCO:B0021260 ! TF2LY_HUMAN relationship: has_participant CCO:B0021266 ! TGIF2_HUMAN relationship: has_participant CCO:B0021706 ! CITE1_HUMAN relationship: has_participant CCO:B0021707 ! CITE4_HUMAN relationship: has_participant CCO:B0022038 ! ZHX2_HUMAN relationship: has_participant CCO:B0022040 ! ZHX3_HUMAN relationship: has_participant CCO:B0022042 ! Q6NUJ7_HUMAN relationship: has_participant CCO:B0022045 ! Q5JZ70_HUMAN relationship: has_participant CCO:B0022223 ! ID1_HUMAN relationship: has_participant CCO:B0022226 ! ID4_HUMAN relationship: has_participant CCO:B0022296 ! Q3LRW1_HUMAN relationship: has_participant CCO:B0022298 ! Q3LRW4_HUMAN relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0022308 ! Q1MSW9_HUMAN relationship: has_participant CCO:B0022312 ! Q3LRW3_HUMAN relationship: has_participant CCO:B0022444 ! TF2B_HUMAN relationship: has_participant CCO:B0023418 ! STAT4_HUMAN relationship: has_participant CCO:B0023422 ! STAT2_HUMAN relationship: has_participant CCO:B0024266 ! POGZ_HUMAN relationship: has_participant CCO:B0024549 ! Q4LE28_HUMAN relationship: has_participant CCO:B0024552 ! O60424_HUMAN relationship: has_participant CCO:B0025035 ! Q7Z324_HUMAN relationship: has_participant CCO:B0026502 ! A8MVD0_HUMAN relationship: has_participant CCO:B0026530 ! NPAS2_HUMAN relationship: has_participant CCO:B0026531 ! CLOCK_HUMAN relationship: has_participant CCO:B0026532 ! Q53EU0_HUMAN relationship: has_participant CCO:B0026534 ! A6NP27_HUMAN relationship: has_participant CCO:B0028072 ! Q5JTM4_HUMAN relationship: has_participant CCO:B0028073 ! RFX3_HUMAN relationship: has_participant CCO:B0028074 ! RFX2_HUMAN relationship: has_participant CCO:B0028081 ! A8K581_HUMAN relationship: has_participant CCO:B0028088 ! Q5JTM3_HUMAN relationship: has_participant CCO:B0028510 ! MYBA_HUMAN relationship: has_participant CCO:B0028526 ! A8MXH7_HUMAN relationship: has_participant CCO:B0028528 ! Q495F9_HUMAN relationship: has_participant CCO:B0028530 ! Q5THS6_HUMAN relationship: has_participant CCO:B0028532 ! Q708E2_HUMAN relationship: has_participant CCO:B0029480 ! Q8NHM1_HUMAN relationship: has_participant CCO:B0029482 ! LHX3_HUMAN relationship: has_participant CCO:B0029488 ! Q9HBU2_HUMAN relationship: has_participant CCO:B0029685 ! STAT6_HUMAN relationship: has_participant CCO:B0030504 ! Q5VVI0_HUMAN relationship: has_participant CCO:B0030506 ! NGN2_HUMAN relationship: has_participant CCO:B0030509 ! NGN3_HUMAN relationship: has_participant CCO:B0030784 ! FUSIP_HUMAN relationship: has_participant CCO:B0031066 ! MKX_HUMAN relationship: has_participant CCO:B0031067 ! IRX5_HUMAN relationship: has_participant CCO:B0031069 ! IRX2_HUMAN relationship: has_participant CCO:B0031070 ! IRX3_HUMAN relationship: has_participant CCO:B0031071 ! IRX1_HUMAN relationship: has_participant CCO:B0031646 ! Q6S731_HUMAN relationship: has_participant CCO:B0031650 ! Q6S729_HUMAN relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0031655 ! Q6S732_HUMAN relationship: has_participant CCO:B0031656 ! Q6S728_HUMAN relationship: has_participant CCO:B0031660 ! Q6S730_HUMAN relationship: has_participant CCO:B0031661 ! PAX2_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0031899 ! NARFL_HUMAN relationship: has_participant CCO:B0032380 ! NF2L1_HUMAN relationship: has_participant CCO:B0032381 ! Q8NF22_HUMAN relationship: has_participant CCO:B0032483 ! ME3L1_HUMAN relationship: has_participant CCO:B0032489 ! MEIS1_HUMAN relationship: has_participant CCO:B0032495 ! Q4G0U8_HUMAN relationship: has_participant CCO:B0032498 ! A8MWD5_HUMAN relationship: has_participant CCO:B0032499 ! MEIS2_HUMAN relationship: has_participant CCO:B0032501 ! MEIS3_HUMAN relationship: has_participant CCO:B0032504 ! ME3L2_HUMAN relationship: has_participant CCO:B0032508 ! Q96DI2_HUMAN relationship: has_participant CCO:B0032530 ! Q7KZF6_HUMAN relationship: has_participant CCO:B0032532 ! Q5VZV8_HUMAN relationship: has_participant CCO:B0033616 ! A8MV94_HUMAN relationship: has_participant CCO:B0033618 ! Q2TAM6_HUMAN relationship: has_participant CCO:B0033619 ! RUNX1_HUMAN relationship: has_participant CCO:B0033620 ! Q5T802_HUMAN relationship: has_participant CCO:B0033622 ! RUNX2_HUMAN relationship: has_participant CCO:B0033733 ! MAFB_HUMAN relationship: has_participant CCO:B0033734 ! MAF_HUMAN relationship: has_participant CCO:B0036287 ! HILS1_HUMAN relationship: has_participant CCO:B0036788 ! GBX2_HUMAN relationship: has_participant CCO:B0036789 ! HXB8_HUMAN relationship: has_participant CCO:B0036790 ! HXB5_HUMAN relationship: has_participant CCO:B0036792 ! HXD4_HUMAN relationship: has_participant CCO:B0036793 ! HXA7_HUMAN relationship: has_participant CCO:B0036796 ! GBX1_HUMAN relationship: has_participant CCO:B0036797 ! HXB4_HUMAN relationship: has_participant CCO:B0036799 ! HXB7_HUMAN relationship: has_participant CCO:B0036801 ! HXA5_HUMAN relationship: has_participant CCO:B0036803 ! Q4VAU3_HUMAN relationship: has_participant CCO:B0036805 ! PDX1_HUMAN relationship: has_participant CCO:B0036807 ! CDX1_HUMAN relationship: has_participant CCO:B0036808 ! Q86TF7_HUMAN relationship: has_participant CCO:B0036810 ! GSX1_HUMAN relationship: has_participant CCO:B0036813 ! HXC5_HUMAN relationship: has_participant CCO:B0036814 ! HXA6_HUMAN relationship: has_participant CCO:B0036816 ! HXC4_HUMAN relationship: has_participant CCO:B0036818 ! HXC6_HUMAN relationship: has_participant CCO:B0036820 ! Q9UD61_HUMAN relationship: has_participant CCO:B0036821 ! HXD8_HUMAN relationship: has_participant CCO:B0036822 ! O75805_HUMAN relationship: has_participant CCO:B0036823 ! MNX1_HUMAN relationship: has_participant CCO:B0036825 ! HXA4_HUMAN relationship: has_participant CCO:B0036826 ! HXB6_HUMAN relationship: has_participant CCO:B0036827 ! HXC8_HUMAN relationship: has_participant CCO:B0036828 ! HXD9_HUMAN relationship: has_participant CCO:B0036829 ! CDX2_HUMAN relationship: has_participant CCO:B0036830 ! A8MYQ3_HUMAN relationship: has_participant CCO:B0036831 ! A1L0T6_HUMAN relationship: has_participant CCO:B0036832 ! GSX2_HUMAN relationship: has_participant CCO:B0036835 ! Q16124_HUMAN relationship: has_participant CCO:B0036838 ! HXB9_HUMAN relationship: has_participant CCO:B0037981 ! DBX1_HUMAN relationship: has_participant CCO:B0037982 ! DLX2_HUMAN relationship: has_participant CCO:B0037983 ! DLX6_HUMAN relationship: has_participant CCO:B0037984 ! DLX4_HUMAN relationship: has_participant CCO:B0037985 ! BSH_HUMAN relationship: has_participant CCO:B0037986 ! Q59HD6_HUMAN relationship: has_participant CCO:B0037988 ! NKX62_HUMAN relationship: has_participant CCO:B0037989 ! DLX5_HUMAN relationship: has_participant CCO:B0037990 ! DLX3_HUMAN relationship: has_participant CCO:B0037991 ! NKX61_HUMAN relationship: has_participant CCO:B0038614 ! A6NJ87_HUMAN relationship: has_participant CCO:B0039136 ! TIGD3_HUMAN relationship: has_participant CCO:B0039905 ! TLE6_HUMAN relationship: has_participant CCO:B0039910 ! A8MSP9_HUMAN relationship: has_participant CCO:B0040687 ! CUX1_HUMAN relationship: has_participant CCO:B0041267 ! DMTF1_HUMAN relationship: has_participant CCO:B0041948 ! NRK_HUMAN relationship: has_participant CCO:B0042178 ! MAFG_HUMAN relationship: has_participant CCO:B0042180 ! MAFF_HUMAN relationship: has_participant CCO:B0042181 ! B0QY71_HUMAN relationship: has_participant CCO:B0042182 ! B0QY70_HUMAN relationship: has_participant CCO:B0042184 ! A8WFP5_HUMAN relationship: has_participant CCO:B0042185 ! MAFA_HUMAN relationship: has_participant CCO:B0042408 ! HIF3A_HUMAN relationship: has_participant CCO:B0042415 ! A8MYV6_HUMAN relationship: has_participant CCO:B0042816 ! T2H2L_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN relationship: has_participant CCO:B0043450 ! RB15B_HUMAN relationship: has_participant CCO:B0043827 ! HHEX_HUMAN relationship: has_participant CCO:B0048650 ! PO4F1_HUMAN relationship: has_participant CCO:B0048651 ! PO4F3_HUMAN relationship: has_participant CCO:B0048652 ! PIT1_HUMAN relationship: has_participant CCO:B0048653 ! PO5L1_HUMAN relationship: has_participant CCO:B0048655 ! PO3F2_HUMAN relationship: has_participant CCO:B0048656 ! PO5F1_HUMAN relationship: has_participant CCO:B0048659 ! Q5TAG2_HUMAN relationship: has_participant CCO:B0048661 ! PO3F4_HUMAN relationship: has_participant CCO:B0048662 ! PO5F2_HUMAN relationship: has_participant CCO:B0048672 ! Q2VIK6_HUMAN relationship: has_participant CCO:B0048883 ! TAD2A_HUMAN relationship: has_participant CCO:B0049067 ! HNF6_HUMAN relationship: has_participant CCO:B0049069 ! ONEC3_HUMAN relationship: has_participant CCO:B0049070 ! ONEC2_HUMAN relationship: has_participant CCO:B0049259 ! B0QYS6_HUMAN relationship: has_participant CCO:B0049260 ! TFEB_HUMAN relationship: has_participant CCO:B0049261 ! B0QYS7_HUMAN relationship: has_participant CCO:B0049262 ! TFE3_HUMAN relationship: has_participant CCO:B0049263 ! B1AKB4_HUMAN relationship: has_participant CCO:B0049264 ! B1AKB5_HUMAN relationship: has_participant CCO:B0049757 ! CNOT2_HUMAN relationship: has_participant CCO:B0049929 ! SRBP1_HUMAN relationship: has_participant CCO:B0049933 ! Q05BD5_HUMAN relationship: has_participant CCO:B0049934 ! SRBP2_HUMAN relationship: has_participant CCO:B0050234 ! A7E2Y4_HUMAN relationship: has_participant CCO:B0050348 ! AHRR_HUMAN relationship: has_participant CCO:B0050546 ! TF3B_HUMAN relationship: has_participant CCO:B0050549 ! Q96KX3_HUMAN relationship: has_participant CCO:B0051378 ! Q29675_HUMAN relationship: has_participant CCO:B0051380 ! C2TA_HUMAN relationship: has_participant CCO:B0051381 ! A0N0N9_HUMAN relationship: has_participant CCO:B0051382 ! Q8SNB7_HUMAN relationship: has_participant CCO:B0051384 ! Q8SNB8_HUMAN relationship: has_participant CCO:B0053708 ! A1ECB1_HUMAN relationship: has_participant CCO:B0053709 ! A1ECB2_HUMAN relationship: has_participant CCO:B0053715 ! A2A2C9_HUMAN relationship: has_participant CCO:B0053730 ! A2I2N6_HUMAN relationship: has_participant CCO:B0053731 ! A2IDC6_HUMAN relationship: has_participant CCO:B0053732 ! A2IDC7_HUMAN relationship: has_participant CCO:B0053735 ! A2RRB4_HUMAN relationship: has_participant CCO:B0053740 ! HMX2_HUMAN relationship: has_participant CCO:B0053749 ! A4D0Z1_HUMAN relationship: has_participant CCO:B0053750 ! A4D182_HUMAN relationship: has_participant CCO:B0053774 ! A5PKU7_HUMAN relationship: has_participant CCO:B0053789 ! A6ND77_HUMAN relationship: has_participant CCO:B0053819 ! HELT_HUMAN relationship: has_participant CCO:B0053843 ! A6NH73_HUMAN relationship: has_participant CCO:B0053844 ! A6NH88_HUMAN relationship: has_participant CCO:B0053855 ! MSGN1_HUMAN relationship: has_participant CCO:B0053894 ! YE016_HUMAN relationship: has_participant CCO:B0053895 ! EA3L2_HUMAN relationship: has_participant CCO:B0053896 ! A6NLG4_HUMAN relationship: has_participant CCO:B0053907 ! A6NMM4_HUMAN relationship: has_participant CCO:B0053926 ! A6PVQ1_HUMAN relationship: has_participant CCO:B0053927 ! A6PVQ2_HUMAN relationship: has_participant CCO:B0053936 ! A6PVY9_HUMAN relationship: has_participant CCO:B0053937 ! A6PW55_HUMAN relationship: has_participant CCO:B0053964 ! A8K3M1_HUMAN relationship: has_participant CCO:B0053982 ! A8K9D9_HUMAN relationship: has_participant CCO:B0054016 ! A8MSX5_HUMAN relationship: has_participant CCO:B0054030 ! A8MTL8_HUMAN relationship: has_participant CCO:B0054033 ! NOTO_HUMAN relationship: has_participant CCO:B0054056 ! VGLL3_HUMAN relationship: has_participant CCO:B0054072 ! A8MW16_HUMAN relationship: has_participant CCO:B0054078 ! A8MWF9_HUMAN relationship: has_participant CCO:B0054084 ! A8MWY4_HUMAN relationship: has_participant CCO:B0054087 ! A8MX14_HUMAN relationship: has_participant CCO:B0054125 ! A8MYM2_HUMAN relationship: has_participant CCO:B0054137 ! LEUTX_HUMAN relationship: has_participant CCO:B0054149 ! A9C4B1_HUMAN relationship: has_participant CCO:B0054159 ! A9Z1Z2_HUMAN relationship: has_participant CCO:B0054167 ! B0QYL8_HUMAN relationship: has_participant CCO:B0054168 ! B0QYL9_HUMAN relationship: has_participant CCO:B0054170 ! B0QYT0_HUMAN relationship: has_participant CCO:B0054171 ! B0QYU3_HUMAN relationship: has_participant CCO:B0054193 ! B0V3I0_HUMAN relationship: has_participant CCO:B0054260 ! B1ANN6_HUMAN relationship: has_participant CCO:B0054261 ! B1ANN7_HUMAN relationship: has_participant CCO:B0054262 ! B1ANN8_HUMAN relationship: has_participant CCO:B0054263 ! B1ANN9_HUMAN relationship: has_participant CCO:B0054264 ! B1ANP5_HUMAN relationship: has_participant CCO:B0054265 ! B1ANP6_HUMAN relationship: has_participant CCO:B0054266 ! B1ANP7_HUMAN relationship: has_participant CCO:B0054269 ! B1APE1_HUMAN relationship: has_participant CCO:B0054270 ! B1APE2_HUMAN relationship: has_participant CCO:B0054277 ! B1AQP1_HUMAN relationship: has_participant CCO:B0054284 ! B1B1I8_HUMAN relationship: has_participant CCO:B0054285 ! B1B1I9_HUMAN relationship: has_participant CCO:B0054286 ! B1B1J0_HUMAN relationship: has_participant CCO:B0054311 ! BMAL1_HUMAN relationship: has_participant CCO:B0054325 ! NR5A2_HUMAN relationship: has_participant CCO:B0054361 ! CDX4_HUMAN relationship: has_participant CCO:B0054380 ! PHX2A_HUMAN relationship: has_participant CCO:B0054384 ! BACH1_HUMAN relationship: has_participant CCO:B0054393 ! TFEC_HUMAN relationship: has_participant CCO:B0054413 ! BRAC_HUMAN relationship: has_participant CCO:B0054422 ! SHOX_HUMAN relationship: has_participant CCO:B0054439 ! GSC2_HUMAN relationship: has_participant CCO:B0054456 ! CRX_HUMAN relationship: has_participant CCO:B0054462 ! HXC11_HUMAN relationship: has_participant CCO:B0054471 ! PAX4_HUMAN relationship: has_participant CCO:B0054475 ! HXA2_HUMAN relationship: has_participant CCO:B0054476 ! HXA3_HUMAN relationship: has_participant CCO:B0054477 ! O43372_HUMAN relationship: has_participant CCO:B0054479 ! O43392_HUMAN relationship: has_participant CCO:B0054494 ! O43582_HUMAN relationship: has_participant CCO:B0054510 ! TCF21_HUMAN relationship: has_participant CCO:B0054512 ! TLX3_HUMAN relationship: has_participant CCO:B0054519 ! TLX2_HUMAN relationship: has_participant CCO:B0054521 ! DUX1_HUMAN relationship: has_participant CCO:B0054551 ! NOBOX_HUMAN relationship: has_participant CCO:B0054556 ! FADS1_HUMAN relationship: has_participant CCO:B0054557 ! O60428_HUMAN relationship: has_participant CCO:B0054560 ! O60466_HUMAN relationship: has_participant CCO:B0054572 ! LMX1B_HUMAN relationship: has_participant CCO:B0054575 ! MUSC_HUMAN relationship: has_participant CCO:B0054580 ! TBX19_HUMAN relationship: has_participant CCO:B0054582 ! EDF1_HUMAN relationship: has_participant CCO:B0054588 ! SHOX2_HUMAN relationship: has_participant CCO:B0054595 ! MITF_HUMAN relationship: has_participant CCO:B0054611 ! CNOT3_HUMAN relationship: has_participant CCO:B0054616 ! O75321_HUMAN relationship: has_participant CCO:B0054622 ! PROP1_HUMAN relationship: has_participant CCO:B0054624 ! PITX3_HUMAN relationship: has_participant CCO:B0054626 ! NCOR1_HUMAN relationship: has_participant CCO:B0054637 ! SAP30_HUMAN relationship: has_participant CCO:B0054645 ! DUX2_HUMAN relationship: has_participant CCO:B0054669 ! O75806_HUMAN relationship: has_participant CCO:B0054712 ! NFAT5_HUMAN relationship: has_participant CCO:B0054721 ! ALX3_HUMAN relationship: has_participant CCO:B0054723 ! NKX22_HUMAN relationship: has_participant CCO:B0054731 ! ZFPL1_HUMAN relationship: has_participant CCO:B0054738 ! VENTX_HUMAN relationship: has_participant CCO:B0054749 ! SIX3_HUMAN relationship: has_participant CCO:B0054766 ! SIX6_HUMAN relationship: has_participant CCO:B0054779 ! NFAC1_HUMAN relationship: has_participant CCO:B0054806 ! EOMES_HUMAN relationship: has_participant CCO:B0054819 ! HAND1_HUMAN relationship: has_participant CCO:B0054887 ! MYCN_HUMAN relationship: has_participant CCO:B0054918 ! ZFY_HUMAN relationship: has_participant CCO:B0054940 ! PO2F2_HUMAN relationship: has_participant CCO:B0054963 ! RHF2B_HUMAN relationship: has_participant CCO:B0055000 ! MYCL1_HUMAN relationship: has_participant CCO:B0055001 ! MYCL2_HUMAN relationship: has_participant CCO:B0055008 ! LYL1_HUMAN relationship: has_participant CCO:B0055012 ! MYF5_HUMAN relationship: has_participant CCO:B0055026 ! HXB3_HUMAN relationship: has_participant CCO:B0055027 ! HXB2_HUMAN relationship: has_participant CCO:B0055028 ! HXB1_HUMAN relationship: has_participant CCO:B0055031 ! MYOG_HUMAN relationship: has_participant CCO:B0055043 ! PAX1_HUMAN relationship: has_participant CCO:B0055049 ! GCF_HUMAN relationship: has_participant CCO:B0055062 ! ZFX_HUMAN relationship: has_participant CCO:B0055071 ! ZNF22_HUMAN relationship: has_participant CCO:B0055089 ! JUND_HUMAN relationship: has_participant CCO:B0055090 ! TAL1_HUMAN relationship: has_participant CCO:B0055092 ! EGLN_HUMAN relationship: has_participant CCO:B0055109 ! HME2_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0055146 ! USF1_HUMAN relationship: has_participant CCO:B0055153 ! TCEA1_HUMAN relationship: has_participant CCO:B0055156 ! MYF6_HUMAN relationship: has_participant CCO:B0055163 ! PAX7_HUMAN relationship: has_participant CCO:B0055164 ! PAX3_HUMAN relationship: has_participant CCO:B0055202 ! HXD10_HUMAN relationship: has_participant CCO:B0055203 ! MSX1_HUMAN relationship: has_participant CCO:B0055234 ! HXD3_HUMAN relationship: has_participant CCO:B0055236 ! HXA9_HUMAN relationship: has_participant CCO:B0055237 ! HXA11_HUMAN relationship: has_participant CCO:B0055238 ! HXA13_HUMAN relationship: has_participant CCO:B0055239 ! HXC9_HUMAN relationship: has_participant CCO:B0055240 ! HXC12_HUMAN relationship: has_participant CCO:B0055241 ! HXC13_HUMAN relationship: has_participant CCO:B0055242 ! HXD11_HUMAN relationship: has_participant CCO:B0055243 ! TLX1_HUMAN relationship: has_participant CCO:B0055254 ! OTX1_HUMAN relationship: has_participant CCO:B0055255 ! OTX2_HUMAN relationship: has_participant CCO:B0055291 ! HXD12_HUMAN relationship: has_participant CCO:B0055292 ! HXD13_HUMAN relationship: has_participant CCO:B0055294 ! MSX2_HUMAN relationship: has_participant CCO:B0055299 ! HNF1B_HUMAN relationship: has_participant CCO:B0055314 ! RPB9_HUMAN relationship: has_participant CCO:B0055329 ! PBX1_HUMAN relationship: has_participant CCO:B0055330 ! PBX3_HUMAN relationship: has_participant CCO:B0055348 ! LAP2A_HUMAN relationship: has_participant CCO:B0055370 ! NKX21_HUMAN relationship: has_participant CCO:B0055371 ! ABCG1_HUMAN relationship: has_participant CCO:B0055411 ! LHX1_HUMAN relationship: has_participant CCO:B0055426 ! HXA1_HUMAN relationship: has_participant CCO:B0055427 ! EVX1_HUMAN relationship: has_participant CCO:B0055445 ! MEOX1_HUMAN relationship: has_participant CCO:B0055451 ! LHX2_HUMAN relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN relationship: has_participant CCO:B0055506 ! NKX25_HUMAN relationship: has_participant CCO:B0055507 ! LBX1_HUMAN relationship: has_participant CCO:B0055517 ! PRRX1_HUMAN relationship: has_participant CCO:B0055518 ! NRL_HUMAN relationship: has_participant CCO:B0055535 ! PKNX1_HUMAN relationship: has_participant CCO:B0055536 ! PAX9_HUMAN relationship: has_participant CCO:B0055539 ! DLX1_HUMAN relationship: has_participant CCO:B0055553 ! GSC_HUMAN relationship: has_participant CCO:B0055569 ! VSX2_HUMAN relationship: has_participant CCO:B0055606 ! RPAB2_HUMAN relationship: has_participant CCO:B0055608 ! HAND2_HUMAN relationship: has_participant CCO:B0055610 ! ISL1_HUMAN relationship: has_participant CCO:B0055615 ! BTG1_HUMAN relationship: has_participant CCO:B0055622 ! RPAB5_HUMAN relationship: has_participant CCO:B0055638 ! PITX1_HUMAN relationship: has_participant CCO:B0055642 ! NKX32_HUMAN relationship: has_participant CCO:B0055643 ! IRX6_HUMAN relationship: has_participant CCO:B0055644 ! IRX4_HUMAN relationship: has_participant CCO:B0055646 ! PO6F2_HUMAN relationship: has_participant CCO:B0055654 ! SIM1_HUMAN relationship: has_participant CCO:B0055656 ! SSBP2_HUMAN relationship: has_participant CCO:B0055693 ! TFAP4_HUMAN relationship: has_participant CCO:B0055711 ! HEN1_HUMAN relationship: has_participant CCO:B0055712 ! HEN2_HUMAN relationship: has_participant CCO:B0055726 ! EVX2_HUMAN relationship: has_participant CCO:B0055733 ! EMX1_HUMAN relationship: has_participant CCO:B0055734 ! EMX2_HUMAN relationship: has_participant CCO:B0055737 ! REL_HUMAN relationship: has_participant CCO:B0055746 ! HME1_HUMAN relationship: has_participant CCO:B0055750 ! MBTD1_HUMAN relationship: has_participant CCO:B0055751 ! Q05BS4_HUMAN relationship: has_participant CCO:B0055753 ! Q05BW2_HUMAN relationship: has_participant CCO:B0055761 ! Q05D88_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN relationship: has_participant CCO:B0055771 ! PAX8_HUMAN relationship: has_participant CCO:B0055811 ! Q0GM61_HUMAN relationship: has_participant CCO:B0055827 ! MESP2_HUMAN relationship: has_participant CCO:B0055846 ! BPTF_HUMAN relationship: has_participant CCO:B0055847 ! PO4F2_HUMAN relationship: has_participant CCO:B0055852 ! TCF15_HUMAN relationship: has_participant CCO:B0055859 ! NFAC3_HUMAN relationship: has_participant CCO:B0055868 ! PRDM2_HUMAN relationship: has_participant CCO:B0055871 ! RM28_HUMAN relationship: has_participant CCO:B0055886 ! TBX2_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN relationship: has_participant CCO:B0055921 ! OLIG2_HUMAN relationship: has_participant CCO:B0055926 ! Q13537_HUMAN relationship: has_participant CCO:B0055929 ! NDF1_HUMAN relationship: has_participant CCO:B0055940 ! AVR2B_HUMAN relationship: has_participant CCO:B0055949 ! KLF9_HUMAN relationship: has_participant CCO:B0055962 ! KEAP1_HUMAN relationship: has_participant CCO:B0055969 ! SIM2_HUMAN relationship: has_participant CCO:B0055974 ! ELOA1_HUMAN relationship: has_participant CCO:B0055980 ! Q14333_HUMAN relationship: has_participant CCO:B0055986 ! HES1_HUMAN relationship: has_participant CCO:B0055991 ! Q14547_HUMAN relationship: has_participant CCO:B0055992 ! Q14548_HUMAN relationship: has_participant CCO:B0056010 ! Q14663_HUMAN relationship: has_participant CCO:B0056012 ! HLX_HUMAN relationship: has_participant CCO:B0056016 ! Q14803_HUMAN relationship: has_participant CCO:B0056018 ! CHD4_HUMAN relationship: has_participant CCO:B0056019 ! PO6F1_HUMAN relationship: has_participant CCO:B0056026 ! NFAC4_HUMAN relationship: has_participant CCO:B0056035 ! Q14DW8_HUMAN relationship: has_participant CCO:B0056051 ! NKX11_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056069 ! SIX1_HUMAN relationship: has_participant CCO:B0056072 ! TAF11_HUMAN relationship: has_participant CCO:B0056073 ! TAF7_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0056092 ! TRIP4_HUMAN relationship: has_participant CCO:B0056094 ! RHOH_HUMAN relationship: has_participant CCO:B0056095 ! TWST1_HUMAN relationship: has_participant CCO:B0056097 ! ALX1_HUMAN relationship: has_participant CCO:B0056111 ! NDF2_HUMAN relationship: has_participant CCO:B0056112 ! NCOA1_HUMAN relationship: has_participant CCO:B0056117 ! USF2_HUMAN relationship: has_participant CCO:B0056118 ! ZFHX3_HUMAN relationship: has_participant CCO:B0056129 ! NF2L2_HUMAN relationship: has_participant CCO:B0056151 ! TAL2_HUMAN relationship: has_participant CCO:B0056162 ! NFE2_HUMAN relationship: has_participant CCO:B0056168 ! TBR1_HUMAN relationship: has_participant CCO:B0056185 ! TIGD6_HUMAN relationship: has_participant CCO:B0056187 ! Q17RU2_HUMAN relationship: has_participant CCO:B0056197 ! Q24JR0_HUMAN relationship: has_participant CCO:B0056206 ! ISX_HUMAN relationship: has_participant CCO:B0056220 ! Q2PJS5_HUMAN relationship: has_participant CCO:B0056227 ! Q2TAM5_HUMAN relationship: has_participant CCO:B0056230 ! Q2TB39_HUMAN relationship: has_participant CCO:B0056238 ! Q32MC2_HUMAN relationship: has_participant CCO:B0056246 ! PROX2_HUMAN relationship: has_participant CCO:B0056249 ! Q3KNR4_HUMAN relationship: has_participant CCO:B0056263 ! Q3MIY3_HUMAN relationship: has_participant CCO:B0056272 ! EA3L1_HUMAN relationship: has_participant CCO:B0056281 ! Q3ZB87_HUMAN relationship: has_participant CCO:B0056289 ! Q494T1_HUMAN relationship: has_participant CCO:B0056291 ! Q494Z3_HUMAN relationship: has_participant CCO:B0056292 ! Q494Z4_HUMAN relationship: has_participant CCO:B0056318 ! Q4KMP4_HUMAN relationship: has_participant CCO:B0056321 ! Q4TT37_HUMAN relationship: has_participant CCO:B0056322 ! Q4TT38_HUMAN relationship: has_participant CCO:B0056329 ! Q4VAU5_HUMAN relationship: has_participant CCO:B0056335 ! TIGD2_HUMAN relationship: has_participant CCO:B0056338 ! Q4ZG35_HUMAN relationship: has_participant CCO:B0056339 ! Q4ZG44_HUMAN relationship: has_participant CCO:B0056348 ! TIGD5_HUMAN relationship: has_participant CCO:B0056378 ! Q59ED4_HUMAN relationship: has_participant CCO:B0056379 ! Q59EI7_HUMAN relationship: has_participant CCO:B0056395 ! Q59FT1_HUMAN relationship: has_participant CCO:B0056398 ! Q59G74_HUMAN relationship: has_participant CCO:B0056406 ! Q59GG3_HUMAN relationship: has_participant CCO:B0056410 ! Q59GM0_HUMAN relationship: has_participant CCO:B0056432 ! Q5H8Y7_HUMAN relationship: has_participant CCO:B0056433 ! Q5H8Y9_HUMAN relationship: has_participant CCO:B0056434 ! Q5H914_HUMAN relationship: has_participant CCO:B0056435 ! Q5H915_HUMAN relationship: has_participant CCO:B0056440 ! TAF7L_HUMAN relationship: has_participant CCO:B0056448 ! Q5ISC7_HUMAN relationship: has_participant CCO:B0056476 ! Q5JS98_HUMAN relationship: has_participant CCO:B0056486 ! Q5JU95_HUMAN relationship: has_participant CCO:B0056489 ! SOLH1_HUMAN relationship: has_participant CCO:B0056498 ! Q5JXE6_HUMAN relationship: has_participant CCO:B0056522 ! Q5M8T3_HUMAN relationship: has_participant CCO:B0056529 ! Q5QPV0_HUMAN relationship: has_participant CCO:B0056530 ! Q5QPV1_HUMAN relationship: has_participant CCO:B0056534 ! VAX1_HUMAN relationship: has_participant CCO:B0056546 ! Q5SW06_HUMAN relationship: has_participant CCO:B0056550 ! SNPC4_HUMAN relationship: has_participant CCO:B0056559 ! Q5SZP2_HUMAN relationship: has_participant CCO:B0056560 ! Q5SZP3_HUMAN relationship: has_participant CCO:B0056576 ! Q5T4L0_HUMAN relationship: has_participant CCO:B0056577 ! Q5T4L1_HUMAN relationship: has_participant CCO:B0056594 ! Q5T7S7_HUMAN relationship: has_participant CCO:B0056597 ! Q5T980_HUMAN relationship: has_participant CCO:B0056598 ! Q5T981_HUMAN relationship: has_participant CCO:B0056603 ! HES5_HUMAN relationship: has_participant CCO:B0056618 ! Q5TF93_HUMAN relationship: has_participant CCO:B0056622 ! Q5TG85_HUMAN relationship: has_participant CCO:B0056625 ! HES3_HUMAN relationship: has_participant CCO:B0056627 ! Q5THJ1_HUMAN relationship: has_participant CCO:B0056633 ! Q5TIH6_HUMAN relationship: has_participant CCO:B0056652 ! Q5VTZ4_HUMAN relationship: has_participant CCO:B0056653 ! Q5VUE2_HUMAN relationship: has_participant CCO:B0056654 ! Q5VUE6_HUMAN relationship: has_participant CCO:B0056655 ! SMBT2_HUMAN relationship: has_participant CCO:B0056659 ! MYSM1_HUMAN relationship: has_participant CCO:B0056660 ! Q5VVT2_HUMAN relationship: has_participant CCO:B0056683 ! OTP_HUMAN relationship: has_participant CCO:B0056696 ! Q66VZ3_HUMAN relationship: has_participant CCO:B0056698 ! CR3L3_HUMAN relationship: has_participant CCO:B0056702 ! K2018_HUMAN relationship: has_participant CCO:B0056710 ! LHX8_HUMAN relationship: has_participant CCO:B0056844 ! Q6N011_HUMAN relationship: has_participant CCO:B0056853 ! NANP8_HUMAN relationship: has_participant CCO:B0056856 ! TIGD7_HUMAN relationship: has_participant CCO:B0056857 ! Q6NT51_HUMAN relationship: has_participant CCO:B0056858 ! HMBX1_HUMAN relationship: has_participant CCO:B0056875 ! Q6P051_HUMAN relationship: has_participant CCO:B0056887 ! Q6P2R4_HUMAN relationship: has_participant CCO:B0056929 ! FIGLA_HUMAN relationship: has_participant CCO:B0056935 ! Q6RFH8_HUMAN relationship: has_participant CCO:B0056971 ! ASCL4_HUMAN relationship: has_participant CCO:B0056972 ! LBX2_HUMAN relationship: has_participant CCO:B0056975 ! Q6YI47_HUMAN relationship: has_participant CCO:B0056977 ! Q6ZMJ6_HUMAN relationship: has_participant CCO:B0057024 ! DBX2_HUMAN relationship: has_participant CCO:B0057071 ! Q6ZTP8_HUMAN relationship: has_participant CCO:B0057093 ! CR3L2_HUMAN relationship: has_participant CCO:B0057126 ! BHLH8_HUMAN relationship: has_participant CCO:B0057127 ! PTF1A_HUMAN relationship: has_participant CCO:B0057132 ! Q7RTU0_HUMAN relationship: has_participant CCO:B0057133 ! TCF23_HUMAN relationship: has_participant CCO:B0057134 ! OLIG3_HUMAN relationship: has_participant CCO:B0057135 ! BHL42_HUMAN relationship: has_participant CCO:B0057136 ! ASCL5_HUMAN relationship: has_participant CCO:B0057137 ! SCX_HUMAN relationship: has_participant CCO:B0057147 ! Q7Z3D9_HUMAN relationship: has_participant CCO:B0057170 ! Q7Z516_HUMAN relationship: has_participant CCO:B0057172 ! Q7Z566_HUMAN relationship: has_participant CCO:B0057173 ! Q7Z567_HUMAN relationship: has_participant CCO:B0057177 ! Q7Z598_HUMAN relationship: has_participant CCO:B0057178 ! HPC14_HUMAN relationship: has_participant CCO:B0057187 ! Q7Z5Y1_HUMAN relationship: has_participant CCO:B0057241 ! Q86TP4_HUMAN relationship: has_participant CCO:B0057248 ! Q86UH2_HUMAN relationship: has_participant CCO:B0057249 ! ZFHX4_HUMAN relationship: has_participant CCO:B0057252 ! Q86UQ2_HUMAN relationship: has_participant CCO:B0057253 ! Q86UQ3_HUMAN relationship: has_participant CCO:B0057263 ! Q86VM2_HUMAN relationship: has_participant CCO:B0057289 ! Q86XJ5_HUMAN relationship: has_participant CCO:B0057315 ! Q86YY0_HUMAN relationship: has_participant CCO:B0057327 ! Q8IUT4_HUMAN relationship: has_participant CCO:B0057360 ! MGAP_HUMAN relationship: has_participant CCO:B0057368 ! HOMEZ_HUMAN relationship: has_participant CCO:B0057375 ! NPAS3_HUMAN relationship: has_participant CCO:B0057383 ! TIGD4_HUMAN relationship: has_participant CCO:B0057386 ! ELOA2_HUMAN relationship: has_participant CCO:B0057397 ! RCOR2_HUMAN relationship: has_participant CCO:B0057420 ! ATOH7_HUMAN relationship: has_participant CCO:B0057426 ! SIX5_HUMAN relationship: has_participant CCO:B0057485 ! ESX1_HUMAN relationship: has_participant CCO:B0057486 ! IGSF1_HUMAN relationship: has_participant CCO:B0057506 ! NANG2_HUMAN relationship: has_participant CCO:B0057508 ! TPRX1_HUMAN relationship: has_participant CCO:B0057519 ! VGLL2_HUMAN relationship: has_participant CCO:B0057540 ! ASCC1_HUMAN relationship: has_participant CCO:B0057542 ! LMBL4_HUMAN relationship: has_participant CCO:B0057543 ! CCD79_HUMAN relationship: has_participant CCO:B0057547 ! Q8NAM2_HUMAN relationship: has_participant CCO:B0057576 ! Q8NDC7_HUMAN relationship: has_participant CCO:B0057586 ! BHLH4_HUMAN relationship: has_participant CCO:B0057588 ! GMCLL_HUMAN relationship: has_participant CCO:B0057605 ! BHLH5_HUMAN relationship: has_participant CCO:B0057609 ! DMBX1_HUMAN relationship: has_participant CCO:B0057613 ! ELOA3_HUMAN relationship: has_participant CCO:B0057877 ! RHXF1_HUMAN relationship: has_participant CCO:B0057880 ! Q8NHZ1_HUMAN relationship: has_participant CCO:B0057888 ! OLIG1_HUMAN relationship: has_participant CCO:B0057892 ! NKX23_HUMAN relationship: has_participant CCO:B0057900 ! Q8TB74_HUMAN relationship: has_participant CCO:B0057928 ! CHD5_HUMAN relationship: has_participant CCO:B0057949 ! LMX1A_HUMAN relationship: has_participant CCO:B0057958 ! CR3L4_HUMAN relationship: has_participant CCO:B0057994 ! TWST2_HUMAN relationship: has_participant CCO:B0058014 ! Q8WXB7_HUMAN relationship: has_participant CCO:B0058041 ! BMAL2_HUMAN relationship: has_participant CCO:B0058045 ! Q8WYM6_HUMAN relationship: has_participant CCO:B0058095 ! PROX1_HUMAN relationship: has_participant CCO:B0058098 ! HXB13_HUMAN relationship: has_participant CCO:B0058108 ! ATOH1_HUMAN relationship: has_participant CCO:B0058140 ! LMBL2_HUMAN relationship: has_participant CCO:B0058161 ! CR3L1_HUMAN relationship: has_participant CCO:B0058187 ! Q96CY8_HUMAN relationship: has_participant CCO:B0058201 ! Q96E53_HUMAN relationship: has_participant CCO:B0058215 ! SCMH1_HUMAN relationship: has_participant CCO:B0058217 ! Q96GH8_HUMAN relationship: has_participant CCO:B0058223 ! HES6_HUMAN relationship: has_participant CCO:B0058230 ! GMCL1_HUMAN relationship: has_participant CCO:B0058232 ! RAX2_HUMAN relationship: has_participant CCO:B0058245 ! LMBL3_HUMAN relationship: has_participant CCO:B0058261 ! PKNX2_HUMAN relationship: has_participant CCO:B0058285 ! Q96MC1_HUMAN relationship: has_participant CCO:B0058286 ! Q96ME4_HUMAN relationship: has_participant CCO:B0058295 ! TIGD1_HUMAN relationship: has_participant CCO:B0058297 ! Q96N14_HUMAN relationship: has_participant CCO:B0058308 ! NDF6_HUMAN relationship: has_participant CCO:B0058343 ! DUX5_HUMAN relationship: has_participant CCO:B0058344 ! DUX3_HUMAN relationship: has_participant CCO:B0058357 ! ARX_HUMAN relationship: has_participant CCO:B0058380 ! FER3L_HUMAN relationship: has_participant CCO:B0058394 ! ATOH8_HUMAN relationship: has_participant CCO:B0058400 ! RBM15_HUMAN relationship: has_participant CCO:B0058405 ! Q96TB0_HUMAN relationship: has_participant CCO:B0058408 ! HTF4_HUMAN relationship: has_participant CCO:B0058412 ! PHX2B_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: has_participant CCO:B0058441 ! PITX2_HUMAN relationship: has_participant CCO:B0058451 ! NPAS1_HUMAN relationship: has_participant CCO:B0058455 ! NKX31_HUMAN relationship: has_participant CCO:B0058456 ! PRRX2_HUMAN relationship: has_participant CCO:B0058461 ! ASCL2_HUMAN relationship: has_participant CCO:B0058467 ! VGLL1_HUMAN relationship: has_participant CCO:B0058472 ! HOP_HUMAN relationship: has_participant CCO:B0058493 ! MESP1_HUMAN relationship: has_participant CCO:B0058529 ! MAD3_HUMAN relationship: has_participant CCO:B0058576 ! HES7_HUMAN relationship: has_participant CCO:B0058582 ! PBX4_HUMAN relationship: has_participant CCO:B0058585 ! BACH2_HUMAN relationship: has_participant CCO:B0058597 ! BARH1_HUMAN relationship: has_participant CCO:B0058599 ! Q9BZI2_HUMAN relationship: has_participant CCO:B0058609 ! PO5L4_HUMAN relationship: has_participant CCO:B0058615 ! ZFHX2_HUMAN relationship: has_participant CCO:B0058621 ! BHLH3_HUMAN relationship: has_participant CCO:B0058645 ! HXD1_HUMAN relationship: has_participant CCO:B0058660 ! ALX4_HUMAN relationship: has_participant CCO:B0058680 ! LHX5_HUMAN relationship: has_participant CCO:B0058690 ! MIXL1_HUMAN relationship: has_participant CCO:B0058712 ! OFUT1_HUMAN relationship: has_participant CCO:B0058720 ! COE3_HUMAN relationship: has_participant CCO:B0058764 ! COE2_HUMAN relationship: has_participant CCO:B0058765 ! MLXIP_HUMAN relationship: has_participant CCO:B0058771 ! BRF2_HUMAN relationship: has_participant CCO:B0058774 ! SEBOX_HUMAN relationship: has_participant CCO:B0058792 ! BARX1_HUMAN relationship: has_participant CCO:B0058801 ! HES4_HUMAN relationship: has_participant CCO:B0058828 ! NDF4_HUMAN relationship: has_participant CCO:B0058830 ! HMX1_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN relationship: has_participant CCO:B0058848 ! SIX2_HUMAN relationship: has_participant CCO:B0058860 ! ASCL3_HUMAN relationship: has_participant CCO:B0058863 ! LHX9_HUMAN relationship: has_participant CCO:B0058865 ! HEYL_HUMAN relationship: has_participant CCO:B0058907 ! GLRX2_HUMAN relationship: has_participant CCO:B0058947 ! SOLH2_HUMAN relationship: has_participant CCO:B0058958 ! BARH2_HUMAN relationship: has_participant CCO:B0058959 ! Q9NY94_HUMAN relationship: has_participant CCO:B0059013 ! VSX1_HUMAN relationship: has_participant CCO:B0059049 ! POGK_HUMAN relationship: has_participant CCO:B0059070 ! NLK_HUMAN relationship: has_participant CCO:B0059073 ! RBPJL_HUMAN relationship: has_participant CCO:B0059081 ! HEY2_HUMAN relationship: has_participant CCO:B0059089 ! HESX1_HUMAN relationship: has_participant CCO:B0059090 ! DUX4_HUMAN relationship: has_participant CCO:B0059098 ! NKX12_HUMAN relationship: has_participant CCO:B0059130 ! MLX_HUMAN relationship: has_participant CCO:B0059142 ! SMBT1_HUMAN relationship: has_participant CCO:B0059164 ! SIX4_HUMAN relationship: has_participant CCO:B0059166 ! VAX2_HUMAN relationship: has_participant CCO:B0059213 ! TBX21_HUMAN relationship: has_participant CCO:B0059217 ! TCFL5_HUMAN relationship: has_participant CCO:B0059255 ! PPIE_HUMAN relationship: has_participant CCO:B0059261 ! LHX61_HUMAN relationship: has_participant CCO:B0059270 ! SATB2_HUMAN relationship: has_participant CCO:B0059284 ! SCML2_HUMAN relationship: has_participant CCO:B0059302 ! CK009_HUMAN relationship: has_participant CCO:B0059319 ! RX_HUMAN relationship: has_participant CCO:B0059323 ! RPC10_HUMAN relationship: has_participant CCO:B0059348 ! ZN711_HUMAN relationship: has_participant CCO:B0059352 ! LMBL1_HUMAN relationship: has_participant CCO:B0059354 ! Q9Y4A3_HUMAN relationship: has_participant CCO:B0059355 ! NF2L3_HUMAN relationship: has_participant CCO:B0059368 ! HES2_HUMAN relationship: has_participant CCO:B0059376 ! GCFC_HUMAN relationship: has_participant CCO:B0059378 ! HEY1_HUMAN relationship: has_participant CCO:B0059416 ! Q9Y6T0_HUMAN [Term] id: CCO:P0002370 name: regulation of nurse cell apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nurse cell apoptosis." [PMID:11973306] xref: GO:0045477 is_a: CCO:P0002131 ! regulation of apoptosis [Term] id: CCO:P0002371 name: sevenless signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of the sevenless receptor binding to one of its physiological ligands." [GOC:bf] synonym: "sev receptor signaling pathway" EXACT [] synonym: "sev signaling pathway" EXACT [] synonym: "sevenless signalling pathway" EXACT [] xref: GO:0045500 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:P0002372 name: regulation of sevenless signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the sevenless signaling pathway." [GOC:go_curators] synonym: "regulation of sev signaling pathway" EXACT [] synonym: "regulation of sevenless signalling pathway" EXACT [] xref: GO:0045501 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0002371 ! sevenless signaling pathway [Term] id: CCO:P0002373 name: regulation of interleukin-24 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24." [GOC:go_curators] synonym: "regulation of IL-24 biosynthesis" EXACT [] synonym: "regulation of IL-24 biosynthetic process" EXACT [] synonym: "regulation of interleukin-24 anabolism" EXACT [] synonym: "regulation of interleukin-24 biosynthesis" EXACT [] synonym: "regulation of interleukin-24 formation" EXACT [] synonym: "regulation of interleukin-24 synthesis" EXACT [] xref: GO:0045528 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002374 name: regulation of interleukin-25 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25." [GOC:go_curators] synonym: "regulation of IL-25 biosynthesis" EXACT [] synonym: "regulation of IL-25 biosynthetic process" EXACT [] synonym: "regulation of interleukin-25 anabolism" EXACT [] synonym: "regulation of interleukin-25 biosynthesis" EXACT [] synonym: "regulation of interleukin-25 formation" EXACT [] synonym: "regulation of interleukin-25 synthesis" EXACT [] xref: GO:0045529 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002375 name: regulation of interleukin-26 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26." [GOC:go_curators] synonym: "regulation of IL-26 biosynthesis" EXACT [] synonym: "regulation of IL-26 biosynthetic process" EXACT [] synonym: "regulation of interleukin-26 anabolism" EXACT [] synonym: "regulation of interleukin-26 biosynthesis" EXACT [] synonym: "regulation of interleukin-26 formation" EXACT [] synonym: "regulation of interleukin-26 synthesis" EXACT [] xref: GO:0045530 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002376 name: regulation of interleukin-27 biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27." [GOC:go_curators] synonym: "regulation of IL-27 biosynthesis" EXACT [] synonym: "regulation of IL-27 biosynthetic process" EXACT [] synonym: "regulation of interleukin-27 anabolism" EXACT [] synonym: "regulation of interleukin-27 biosynthesis" EXACT [] synonym: "regulation of interleukin-27 formation" EXACT [] synonym: "regulation of interleukin-27 synthesis" EXACT [] xref: GO:0045531 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002377 name: negative regulation of interleukin-24 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24." [GOC:go_curators] synonym: "down regulation of interleukin-24 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-24 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-24 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-24 biosynthetic process" NARROW [] synonym: "negative regulation of IL-24 biosynthesis" EXACT [] synonym: "negative regulation of IL-24 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-24 anabolism" EXACT [] synonym: "negative regulation of interleukin-24 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-24 formation" EXACT [] synonym: "negative regulation of interleukin-24 synthesis" EXACT [] xref: GO:0045532 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002373 ! regulation of interleukin-24 biosynthetic process [Term] id: CCO:P0002378 name: negative regulation of interleukin-25 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25." [GOC:go_curators] synonym: "down regulation of interleukin-25 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-25 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-25 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-25 biosynthetic process" NARROW [] synonym: "negative regulation of IL-25 biosynthesis" EXACT [] synonym: "negative regulation of IL-25 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-25 anabolism" EXACT [] synonym: "negative regulation of interleukin-25 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-25 formation" EXACT [] synonym: "negative regulation of interleukin-25 synthesis" EXACT [] xref: GO:0045533 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002374 ! regulation of interleukin-25 biosynthetic process [Term] id: CCO:P0002379 name: negative regulation of interleukin-26 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26." [GOC:go_curators] synonym: "down regulation of interleukin-26 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-26 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-26 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-26 biosynthetic process" NARROW [] synonym: "negative regulation of IL-26 biosynthesis" EXACT [] synonym: "negative regulation of IL-26 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-26 anabolism" EXACT [] synonym: "negative regulation of interleukin-26 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-26 formation" EXACT [] synonym: "negative regulation of interleukin-26 synthesis" EXACT [] xref: GO:0045534 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002375 ! regulation of interleukin-26 biosynthetic process [Term] id: CCO:P0002380 name: negative regulation of interleukin-27 biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27." [GOC:go_curators] synonym: "down regulation of interleukin-27 biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-27 biosynthetic process" EXACT [] synonym: "downregulation of interleukin-27 biosynthetic process" EXACT [] synonym: "inhibition of interleukin-27 biosynthetic process" NARROW [] synonym: "negative regulation of IL-27 biosynthesis" EXACT [] synonym: "negative regulation of IL-27 biosynthetic process" EXACT [] synonym: "negative regulation of interleukin-27 anabolism" EXACT [] synonym: "negative regulation of interleukin-27 biosynthesis" EXACT [] synonym: "negative regulation of interleukin-27 formation" EXACT [] synonym: "negative regulation of interleukin-27 synthesis" EXACT [] xref: GO:0045535 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002376 ! regulation of interleukin-27 biosynthetic process [Term] id: CCO:P0002381 name: positive regulation of interleukin-24 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24." [GOC:go_curators] synonym: "activation of interleukin-24 biosynthetic process" NARROW [] synonym: "positive regulation of IL-24 biosynthesis" EXACT [] synonym: "positive regulation of IL-24 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-24 anabolism" EXACT [] synonym: "positive regulation of interleukin-24 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-24 formation" EXACT [] synonym: "positive regulation of interleukin-24 synthesis" EXACT [] synonym: "stimulation of interleukin-24 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-24 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-24 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-24 biosynthetic process" EXACT [] xref: GO:0045536 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002373 ! regulation of interleukin-24 biosynthetic process [Term] id: CCO:P0002382 name: positive regulation of interleukin-25 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25." [GOC:go_curators] synonym: "activation of interleukin-25 biosynthetic process" NARROW [] synonym: "positive regulation of IL-25 biosynthesis" EXACT [] synonym: "positive regulation of IL-25 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-25 anabolism" EXACT [] synonym: "positive regulation of interleukin-25 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-25 formation" EXACT [] synonym: "positive regulation of interleukin-25 synthesis" EXACT [] synonym: "stimulation of interleukin-25 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-25 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-25 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-25 biosynthetic process" EXACT [] xref: GO:0045537 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002374 ! regulation of interleukin-25 biosynthetic process [Term] id: CCO:P0002383 name: positive regulation of interleukin-26 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26." [GOC:go_curators] synonym: "activation of interleukin-26 biosynthetic process" NARROW [] synonym: "positive regulation of IL-26 biosynthesis" EXACT [] synonym: "positive regulation of IL-26 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-26 anabolism" EXACT [] synonym: "positive regulation of interleukin-26 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-26 formation" EXACT [] synonym: "positive regulation of interleukin-26 synthesis" EXACT [] synonym: "stimulation of interleukin-26 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-26 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-26 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-26 biosynthetic process" EXACT [] xref: GO:0045538 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002375 ! regulation of interleukin-26 biosynthetic process [Term] id: CCO:P0002384 name: positive regulation of interleukin-27 biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27." [GOC:go_curators] synonym: "activation of interleukin-27 biosynthetic process" NARROW [] synonym: "positive regulation of IL-27 biosynthesis" EXACT [] synonym: "positive regulation of IL-27 biosynthetic process" EXACT [] synonym: "positive regulation of interleukin-27 anabolism" EXACT [] synonym: "positive regulation of interleukin-27 biosynthesis" EXACT [] synonym: "positive regulation of interleukin-27 formation" EXACT [] synonym: "positive regulation of interleukin-27 synthesis" EXACT [] synonym: "stimulation of interleukin-27 biosynthetic process" NARROW [] synonym: "up regulation of interleukin-27 biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-27 biosynthetic process" EXACT [] synonym: "upregulation of interleukin-27 biosynthetic process" EXACT [] xref: GO:0045539 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002376 ! regulation of interleukin-27 biosynthetic process [Term] id: CCO:P0002385 name: regulation of cholesterol biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol." [GOC:go_curators] synonym: "regulation of cholesterol anabolism" EXACT [] synonym: "regulation of cholesterol biosynthesis" EXACT [] synonym: "regulation of cholesterol formation" EXACT [] synonym: "regulation of cholesterol synthesis" EXACT [] xref: GO:0045540 is_a: CCO:P0002962 ! regulation of steroid biosynthetic process relationship: has_participant CCO:B0054690 ! S14L2_HUMAN [Term] id: CCO:P0002386 name: negative regulation of cholesterol biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol." [GOC:go_curators] synonym: "down regulation of cholesterol biosynthetic process" EXACT [] synonym: "down-regulation of cholesterol biosynthetic process" EXACT [] synonym: "downregulation of cholesterol biosynthetic process" EXACT [] synonym: "inhibition of cholesterol biosynthetic process" NARROW [] synonym: "negative regulation of cholesterol anabolism" EXACT [] synonym: "negative regulation of cholesterol biosynthesis" EXACT [] synonym: "negative regulation of cholesterol formation" EXACT [] synonym: "negative regulation of cholesterol synthesis" EXACT [] xref: GO:0045541 is_a: CCO:P0002385 ! regulation of cholesterol biosynthetic process is_a: CCO:P0002623 ! negative regulation of steroid metabolic process relationship: has_participant CCO:B0033014 ! SODC_HUMAN relationship: has_participant CCO:B0055838 ! SCAP_HUMAN [Term] id: CCO:P0002387 name: positive regulation of cholesterol biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol." [GOC:go_curators] synonym: "activation of cholesterol biosynthetic process" NARROW [] synonym: "positive regulation of cholesterol anabolism" EXACT [] synonym: "positive regulation of cholesterol biosynthesis" EXACT [] synonym: "positive regulation of cholesterol formation" EXACT [] synonym: "positive regulation of cholesterol synthesis" EXACT [] synonym: "stimulation of cholesterol biosynthetic process" NARROW [] synonym: "up regulation of cholesterol biosynthetic process" EXACT [] synonym: "up-regulation of cholesterol biosynthetic process" EXACT [] synonym: "upregulation of cholesterol biosynthetic process" EXACT [] xref: GO:0045542 is_a: CCO:P0002385 ! regulation of cholesterol biosynthetic process is_a: CCO:P0002624 ! positive regulation of steroid metabolic process relationship: has_participant CCO:B0005872 ! AAPK1_HUMAN relationship: has_participant CCO:B0054690 ! S14L2_HUMAN relationship: has_participant CCO:B0055371 ! ABCG1_HUMAN [Term] id: CCO:P0002388 name: regulation of TRAIL biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand." [GOC:go_curators] synonym: "regulation of TRAIL anabolism" EXACT [] synonym: "regulation of TRAIL biosynthesis" EXACT [] synonym: "regulation of TRAIL formation" EXACT [] synonym: "regulation of TRAIL synthesis" EXACT [] xref: GO:0045554 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002389 name: negative regulation of TRAIL biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand." [GOC:go_curators] synonym: "down regulation of TRAIL biosynthetic process" EXACT [] synonym: "down-regulation of TRAIL biosynthetic process" EXACT [] synonym: "downregulation of TRAIL biosynthetic process" EXACT [] synonym: "inhibition of TRAIL biosynthetic process" NARROW [] synonym: "negative regulation of TRAIL anabolism" EXACT [] synonym: "negative regulation of TRAIL biosynthesis" EXACT [] synonym: "negative regulation of TRAIL formation" EXACT [] synonym: "negative regulation of TRAIL synthesis" EXACT [] xref: GO:0045555 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002388 ! regulation of TRAIL biosynthetic process [Term] id: CCO:P0002390 name: positive regulation of TRAIL biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand." [GOC:go_curators] synonym: "activation of TRAIL biosynthetic process" NARROW [] synonym: "positive regulation of TRAIL anabolism" EXACT [] synonym: "positive regulation of TRAIL biosynthesis" EXACT [] synonym: "positive regulation of TRAIL formation" EXACT [] synonym: "positive regulation of TRAIL synthesis" EXACT [] synonym: "stimulation of TRAIL biosynthetic process" NARROW [] synonym: "up regulation of TRAIL biosynthetic process" EXACT [] synonym: "up-regulation of TRAIL biosynthetic process" EXACT [] synonym: "upregulation of TRAIL biosynthetic process" EXACT [] xref: GO:0045556 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002388 ! regulation of TRAIL biosynthetic process relationship: has_participant CCO:B0006010 ! TNR8_HUMAN [Term] id: CCO:P0002391 name: regulation of B cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of B cell differentiation." [GOC:go_curators] synonym: "regulation of B lymphocyte differentiation" EXACT [] synonym: "regulation of B-cell differentiation" EXACT [] synonym: "regulation of B-lymphocyte differentiation" EXACT [] xref: GO:0045577 is_a: CCO:P0002433 ! regulation of lymphocyte differentiation is_a: CCO:P0002982 ! regulation of B cell activation relationship: has_participant CCO:B0058559 ! CAR11_HUMAN [Term] id: CCO:P0002392 name: negative regulation of B cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of B cell differentiation." [GOC:go_curators] synonym: "down regulation of B cell differentiation" EXACT [] synonym: "down-regulation of B cell differentiation" EXACT [] synonym: "downregulation of B cell differentiation" EXACT [] synonym: "inhibition of B cell differentiation" NARROW [] synonym: "negative regulation of B lymphocyte differentiation" EXACT [] synonym: "negative regulation of B-cell differentiation" EXACT [] synonym: "negative regulation of B-lymphocyte differentiation" EXACT [] xref: GO:0045578 is_a: CCO:P0002391 ! regulation of B cell differentiation is_a: CCO:P0002434 ! negative regulation of lymphocyte differentiation is_a: CCO:P0002987 ! negative regulation of B cell activation relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0050279 ! HMGB3_HUMAN [Term] id: CCO:P0002393 name: positive regulation of B cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of B cell differentiation." [GOC:go_curators] synonym: "activation of B cell differentiation" NARROW [] synonym: "positive regulation of B lymphocyte differentiation" EXACT [] synonym: "positive regulation of B-cell differentiation" EXACT [] synonym: "positive regulation of B-lymphocyte differentiation" EXACT [] synonym: "stimulation of B cell differentiation" NARROW [] synonym: "up regulation of B cell differentiation" EXACT [] synonym: "up-regulation of B cell differentiation" EXACT [] synonym: "upregulation of B cell differentiation" EXACT [] xref: GO:0045579 is_a: CCO:P0002391 ! regulation of B cell differentiation is_a: CCO:P0002435 ! positive regulation of lymphocyte differentiation is_a: CCO:P0002989 ! positive regulation of B cell activation relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:P0002394 name: regulation of T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell differentiation." [GOC:go_curators] synonym: "regulation of T lymphocyte differentiation" EXACT [] synonym: "regulation of T-cell differentiation" EXACT [] synonym: "regulation of T-lymphocyte differentiation" EXACT [] xref: GO:0045580 is_a: CCO:P0002433 ! regulation of lymphocyte differentiation is_a: CCO:P0002981 ! regulation of T cell activation relationship: has_participant CCO:B0023521 ! CD2_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN relationship: has_participant CCO:B0058862 ! ISK5_HUMAN [Term] id: CCO:P0002395 name: negative regulation of T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation." [GOC:go_curators] synonym: "down regulation of T cell differentiation" EXACT [] synonym: "down-regulation of T cell differentiation" EXACT [] synonym: "downregulation of T cell differentiation" EXACT [] synonym: "inhibition of T cell differentiation" NARROW [] synonym: "negative regulation of T lymphocyte differentiation" EXACT [] synonym: "negative regulation of T-cell differentiation" EXACT [] synonym: "negative regulation of T-lymphocyte differentiation" EXACT [] xref: GO:0045581 is_a: CCO:P0002394 ! regulation of T cell differentiation is_a: CCO:P0002434 ! negative regulation of lymphocyte differentiation is_a: CCO:P0002986 ! negative regulation of T cell activation [Term] id: CCO:P0002396 name: positive regulation of T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation." [GOC:go_curators] synonym: "activation of T cell differentiation" NARROW [] synonym: "positive regulation of T lymphocyte differentiation" EXACT [] synonym: "positive regulation of T-cell differentiation" EXACT [] synonym: "positive regulation of T-lymphocyte differentiation" EXACT [] synonym: "stimulation of T cell differentiation" NARROW [] synonym: "up regulation of T cell differentiation" EXACT [] synonym: "up-regulation of T cell differentiation" EXACT [] synonym: "upregulation of T cell differentiation" EXACT [] xref: GO:0045582 is_a: CCO:P0002394 ! regulation of T cell differentiation is_a: CCO:P0002435 ! positive regulation of lymphocyte differentiation is_a: CCO:P0002988 ! positive regulation of T cell activation relationship: has_participant CCO:B0024369 ! IL7_HUMAN relationship: has_participant CCO:B0055364 ! ZAP70_HUMAN [Term] id: CCO:P0002397 name: regulation of cytotoxic T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation." [GOC:go_curators] synonym: "regulation of cytotoxic T lymphocyte differentiation" EXACT [] synonym: "regulation of cytotoxic T-cell differentiation" EXACT [] synonym: "regulation of cytotoxic T-lymphocyte differentiation" EXACT [] xref: GO:0045583 is_a: CCO:P0002394 ! regulation of T cell differentiation [Term] id: CCO:P0002398 name: negative regulation of cytotoxic T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytotoxic T cell differentiation." [GOC:go_curators] synonym: "down regulation of cytotoxic T cell differentiation" EXACT [] synonym: "down-regulation of cytotoxic T cell differentiation" EXACT [] synonym: "downregulation of cytotoxic T cell differentiation" EXACT [] synonym: "inhibition of cytotoxic T cell differentiation" NARROW [] synonym: "negative regulation of cytotoxic T lymphocyte differentiation" EXACT [] synonym: "negative regulation of cytotoxic T-cell differentiation" EXACT [] synonym: "negative regulation of cytotoxic T-lymphocyte differentiation" EXACT [] xref: GO:0045584 is_a: CCO:P0002395 ! negative regulation of T cell differentiation is_a: CCO:P0002397 ! regulation of cytotoxic T cell differentiation [Term] id: CCO:P0002399 name: positive regulation of cytotoxic T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation." [GOC:go_curators] synonym: "activation of cytotoxic T cell differentiation" NARROW [] synonym: "positive regulation of cytotoxic T lymphocyte differentiation" EXACT [] synonym: "positive regulation of cytotoxic T-cell differentiation" EXACT [] synonym: "positive regulation of cytotoxic T-lymphocyte differentiation" EXACT [] synonym: "stimulation of cytotoxic T cell differentiation" NARROW [] synonym: "up regulation of cytotoxic T cell differentiation" EXACT [] synonym: "up-regulation of cytotoxic T cell differentiation" EXACT [] synonym: "upregulation of cytotoxic T cell differentiation" EXACT [] xref: GO:0045585 is_a: CCO:P0002396 ! positive regulation of T cell differentiation is_a: CCO:P0002397 ! regulation of cytotoxic T cell differentiation relationship: has_participant CCO:B0001388 ! SNUT1_HUMAN [Term] id: CCO:P0002400 name: regulation of gamma-delta T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation." [GOC:go_curators] synonym: "regulation of gamma-delta T lymphocyte differentiation" EXACT [] synonym: "regulation of gamma-delta T-cell differentiation" EXACT [] synonym: "regulation of gamma-delta T-lymphocyte differentiation" EXACT [] xref: GO:0045586 is_a: CCO:P0002394 ! regulation of T cell differentiation is_a: CCO:P0002718 ! regulation of gamma-delta T cell activation [Term] id: CCO:P0002401 name: negative regulation of gamma-delta T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell differentiation." [GOC:go_curators] synonym: "down regulation of gamma-delta T cell differentiation" EXACT [] synonym: "down-regulation of gamma-delta T cell differentiation" EXACT [] synonym: "downregulation of gamma-delta T cell differentiation" EXACT [] synonym: "inhibition of gamma-delta T cell differentiation" NARROW [] synonym: "negative regulation of gamma-delta T lymphocyte differentiation" EXACT [] synonym: "negative regulation of gamma-delta T-cell differentiation" EXACT [] synonym: "negative regulation of gamma-delta T-lymphocyte differentiation" EXACT [] xref: GO:0045587 is_a: CCO:P0002395 ! negative regulation of T cell differentiation is_a: CCO:P0002400 ! regulation of gamma-delta T cell differentiation is_a: CCO:P0002719 ! negative regulation of gamma-delta T cell activation [Term] id: CCO:P0002402 name: positive regulation of gamma-delta T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation." [GOC:go_curators] synonym: "activation of gamma-delta T cell differentiation" NARROW [] synonym: "positive regulation of gamma-delta T lymphocyte differentiation" EXACT [] synonym: "positive regulation of gamma-delta T-cell differentiation" EXACT [] synonym: "positive regulation of gamma-delta T-lymphocyte differentiation" EXACT [] synonym: "stimulation of gamma-delta T cell differentiation" NARROW [] synonym: "up regulation of gamma-delta T cell differentiation" EXACT [] synonym: "up-regulation of gamma-delta T cell differentiation" EXACT [] synonym: "upregulation of gamma-delta T cell differentiation" EXACT [] xref: GO:0045588 is_a: CCO:P0002396 ! positive regulation of T cell differentiation is_a: CCO:P0002400 ! regulation of gamma-delta T cell differentiation is_a: CCO:P0002720 ! positive regulation of gamma-delta T cell activation relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:P0002403 name: regulation of regulatory T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells." [ISBN:0781735149 "Fundamental Immunology"] synonym: "regulation of regulatory T lymphocyte differentiation" EXACT [] synonym: "regulation of regulatory T-cell differentiation" EXACT [] synonym: "regulation of regulatory T-lymphocyte differentiation" EXACT [] synonym: "regulation of suppressor T cell differentiation" EXACT [] synonym: "regulation of suppressor T lymphocyte differentiation" EXACT [] synonym: "regulation of suppressor T-cell differentiation" EXACT [] synonym: "regulation of suppressor T-lymphocyte differentiation" EXACT [] xref: GO:0045589 is_a: CCO:P0002394 ! regulation of T cell differentiation [Term] id: CCO:P0002404 name: negative regulation of regulatory T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells." [ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of regulatory T cell differentiation" EXACT [] synonym: "down-regulation of regulatory T cell differentiation" EXACT [] synonym: "downregulation of regulatory T cell differentiation" EXACT [] synonym: "inhibition of regulatory T cell differentiation" NARROW [] synonym: "negative regulation of regulatory T lymphocyte differentiation" EXACT [] synonym: "negative regulation of regulatory T-cell differentiation" EXACT [] synonym: "negative regulation of regulatory T-lymphocyte differentiation" EXACT [] synonym: "negative regulation of suppressor T cell differentiation" EXACT [] synonym: "negative regulation of suppressor T-cell differentiation" EXACT [] xref: GO:0045590 is_a: CCO:P0002395 ! negative regulation of T cell differentiation is_a: CCO:P0002403 ! regulation of regulatory T cell differentiation [Term] id: CCO:P0002405 name: positive regulation of regulatory T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells." [ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of regulatory T cell differentiation" NARROW [] synonym: "positive regulation of regulatory T lymphocyte differentiation" EXACT [] synonym: "positive regulation of regulatory T-cell differentiation" EXACT [] synonym: "positive regulation of regulatory T-lymphocyte differentiation" EXACT [] synonym: "positive regulation of suppressor T cell differentiation" EXACT [] synonym: "positive regulation of suppressor T-cell differentiation" EXACT [] synonym: "stimulation of regulatory T cell differentiation" NARROW [] synonym: "up regulation of regulatory T cell differentiation" EXACT [] synonym: "up-regulation of regulatory T cell differentiation" EXACT [] synonym: "upregulation of regulatory T cell differentiation" EXACT [] xref: GO:0045591 is_a: CCO:P0002396 ! positive regulation of T cell differentiation is_a: CCO:P0002403 ! regulation of regulatory T cell differentiation [Term] id: CCO:P0002406 name: regulation of cumulus cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation." [GOC:go_curators] synonym: "regulation of ovarian cumulus cell differentiation" EXACT [] xref: GO:0045592 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002407 name: negative regulation of cumulus cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ovarian cumulus cell differentiation." [GOC:go_curators] synonym: "down regulation of cumulus cell differentiation" EXACT [] synonym: "down-regulation of cumulus cell differentiation" EXACT [] synonym: "downregulation of cumulus cell differentiation" EXACT [] synonym: "inhibition of cumulus cell differentiation" NARROW [] synonym: "negative regulation of ovarian cumulus cell differentiation" EXACT [] xref: GO:0045593 is_a: CCO:P0002406 ! regulation of cumulus cell differentiation is_a: CCO:P0002410 ! negative regulation of cell differentiation [Term] id: CCO:P0002408 name: positive regulation of cumulus cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation." [GOC:go_curators] synonym: "activation of cumulus cell differentiation" NARROW [] synonym: "positive regulation of ovarian cumulus cell differentiation" EXACT [] synonym: "stimulation of cumulus cell differentiation" NARROW [] synonym: "up regulation of cumulus cell differentiation" EXACT [] synonym: "up-regulation of cumulus cell differentiation" EXACT [] synonym: "upregulation of cumulus cell differentiation" EXACT [] xref: GO:0045594 is_a: CCO:P0002406 ! regulation of cumulus cell differentiation is_a: CCO:P0002411 ! positive regulation of cell differentiation [Term] id: CCO:P0002409 name: regulation of cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] subset: gosubset_prok xref: GO:0045595 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001571 ! 2AAA_HUMAN relationship: has_participant CCO:B0001680 ! SN1L1_HUMAN relationship: has_participant CCO:B0001697 ! PP2AA_HUMAN relationship: has_participant CCO:B0026671 ! TICN2_HUMAN relationship: has_participant CCO:B0039862 ! KLK6_HUMAN relationship: has_participant CCO:B0048655 ! PO3F2_HUMAN relationship: has_participant CCO:B0054556 ! FADS1_HUMAN relationship: has_participant CCO:B0055549 ! WNT3A_HUMAN relationship: has_participant CCO:B0056004 ! IHH_HUMAN relationship: has_participant CCO:B0057241 ! Q86TP4_HUMAN relationship: has_participant CCO:B0057449 ! LTBP4_HUMAN relationship: has_participant CCO:B0058756 ! NANOG_HUMAN relationship: has_participant CCO:B0059217 ! TCFL5_HUMAN [Term] id: CCO:P0002410 name: negative regulation of cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of cell differentiation" EXACT [] synonym: "down-regulation of cell differentiation" EXACT [] synonym: "downregulation of cell differentiation" EXACT [] synonym: "inhibition of cell differentiation" NARROW [] xref: GO:0045596 is_a: CCO:P0002409 ! regulation of cell differentiation is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0001565 ! MK01_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0005328 ! NOGG_HUMAN relationship: has_participant CCO:B0005850 ! GLI3_HUMAN relationship: has_participant CCO:B0028290 ! JAG1_HUMAN relationship: has_participant CCO:B0028292 ! DLL1_HUMAN relationship: has_participant CCO:B0054756 ! GDF11_HUMAN relationship: has_participant CCO:B0054984 ! IAPP_HUMAN relationship: has_participant CCO:B0056004 ! IHH_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0058414 ! NOTC4_HUMAN relationship: has_participant CCO:B0058472 ! HOP_HUMAN [Term] id: CCO:P0002411 name: positive regulation of cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators] subset: gosubset_prok synonym: "activation of cell differentiation" NARROW [] synonym: "stimulation of cell differentiation" NARROW [] synonym: "up regulation of cell differentiation" EXACT [] synonym: "up-regulation of cell differentiation" EXACT [] synonym: "upregulation of cell differentiation" EXACT [] xref: GO:0045597 is_a: CCO:P0002409 ! regulation of cell differentiation is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001516 ! BMP4_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0006048 ! HSF4_HUMAN relationship: has_participant CCO:B0020371 ! BMR1B_HUMAN relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0054723 ! NKX22_HUMAN relationship: has_participant CCO:B0054980 ! CLUS_HUMAN [Term] id: CCO:P0002412 name: regulation of fat cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "regulation of adipocyte cell differentiation" EXACT [] synonym: "regulation of adipocyte differentiation" EXACT [] xref: GO:0045598 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0057209 ! TAF8_HUMAN [Term] id: CCO:P0002413 name: negative regulation of fat cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "down regulation of fat cell differentiation" EXACT [] synonym: "down-regulation of fat cell differentiation" EXACT [] synonym: "downregulation of fat cell differentiation" EXACT [] synonym: "inhibition of fat cell differentiation" NARROW [] synonym: "negative regulation of adipocyte cell differentiation" EXACT [] synonym: "negative regulation of adipocyte differentiation" EXACT [] xref: GO:0045599 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002412 ! regulation of fat cell differentiation relationship: has_participant CCO:B0055145 ! ENPP1_HUMAN relationship: has_participant CCO:B0058638 ! WWTR1_HUMAN [Term] id: CCO:P0002414 name: positive regulation of fat cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "activation of fat cell differentiation" NARROW [] synonym: "positive regulation of adipocyte cell differentiation" EXACT [] synonym: "positive regulation of adipocyte differentiation" EXACT [] synonym: "stimulation of fat cell differentiation" NARROW [] synonym: "up regulation of fat cell differentiation" EXACT [] synonym: "up-regulation of fat cell differentiation" EXACT [] synonym: "upregulation of fat cell differentiation" EXACT [] xref: GO:0045600 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002412 ! regulation of fat cell differentiation relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0055722 ! PPARD_HUMAN relationship: has_participant CCO:B0055824 ! ADIG_HUMAN [Term] id: CCO:P0002415 name: regulation of endothelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] xref: GO:0045601 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002416 name: negative regulation of endothelial cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "down regulation of endothelial cell differentiation" EXACT [] synonym: "down-regulation of endothelial cell differentiation" EXACT [] synonym: "downregulation of endothelial cell differentiation" EXACT [] synonym: "inhibition of endothelial cell differentiation" NARROW [] xref: GO:0045602 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002415 ! regulation of endothelial cell differentiation relationship: has_participant CCO:B0058414 ! NOTC4_HUMAN [Term] id: CCO:P0002417 name: positive regulation of endothelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "activation of endothelial cell differentiation" NARROW [] synonym: "stimulation of endothelial cell differentiation" NARROW [] synonym: "up regulation of endothelial cell differentiation" EXACT [] synonym: "up-regulation of endothelial cell differentiation" EXACT [] synonym: "upregulation of endothelial cell differentiation" EXACT [] xref: GO:0045603 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002415 ! regulation of endothelial cell differentiation relationship: has_participant CCO:B0055615 ! BTG1_HUMAN [Term] id: CCO:P0002418 name: regulation of epidermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] xref: GO:0045604 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0042178 ! MAFG_HUMAN relationship: has_participant CCO:B0042180 ! MAFF_HUMAN relationship: has_participant CCO:B0055962 ! KEAP1_HUMAN [Term] id: CCO:P0002419 name: negative regulation of epidermal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "down regulation of epidermal cell differentiation" EXACT [] synonym: "down-regulation of epidermal cell differentiation" EXACT [] synonym: "downregulation of epidermal cell differentiation" EXACT [] synonym: "inhibition of epidermal cell differentiation" NARROW [] xref: GO:0045605 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002418 ! regulation of epidermal cell differentiation [Term] id: CCO:P0002420 name: positive regulation of epidermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "activation of epidermal cell differentiation" NARROW [] synonym: "stimulation of epidermal cell differentiation" NARROW [] synonym: "up regulation of epidermal cell differentiation" EXACT [] synonym: "up-regulation of epidermal cell differentiation" EXACT [] synonym: "upregulation of epidermal cell differentiation" EXACT [] xref: GO:0045606 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002418 ! regulation of epidermal cell differentiation relationship: has_participant CCO:B0058987 ! IL20_HUMAN [Term] id: CCO:P0002421 name: regulation of auditory receptor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of auditory hair cell differentiation." [GOC:go_curators] synonym: "regulation of auditory hair cell differentiation" EXACT [] xref: GO:0045607 is_a: CCO:P0002445 ! regulation of mechanoreceptor differentiation [Term] id: CCO:P0002422 name: negative regulation of auditory receptor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of auditory hair cell differentiation." [GOC:go_curators] synonym: "down regulation of auditory receptor cell differentiation" EXACT [] synonym: "down-regulation of auditory receptor cell differentiation" EXACT [] synonym: "downregulation of auditory receptor cell differentiation" EXACT [] synonym: "inhibition of auditory receptor cell differentiation" NARROW [] synonym: "negative regulation of auditory hair cell differentiation" EXACT [] xref: GO:0045608 is_a: CCO:P0002421 ! regulation of auditory receptor cell differentiation is_a: CCO:P0002446 ! negative regulation of mechanoreceptor differentiation relationship: has_participant CCO:B0028292 ! DLL1_HUMAN relationship: has_participant CCO:B0055986 ! HES1_HUMAN [Term] id: CCO:P0002423 name: positive regulation of auditory receptor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation." [GOC:go_curators] synonym: "activation of auditory receptor cell differentiation" NARROW [] synonym: "positive regulation of auditory hair cell differentiation" EXACT [] synonym: "stimulation of auditory receptor cell differentiation" NARROW [] synonym: "up regulation of auditory receptor cell differentiation" EXACT [] synonym: "up-regulation of auditory receptor cell differentiation" EXACT [] synonym: "upregulation of auditory receptor cell differentiation" EXACT [] xref: GO:0045609 is_a: CCO:P0002421 ! regulation of auditory receptor cell differentiation is_a: CCO:P0002447 ! positive regulation of mechanoreceptor differentiation relationship: has_participant CCO:B0058108 ! ATOH1_HUMAN [Term] id: CCO:P0002424 name: regulation of hemocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hemocyte differentiation." [GOC:go_curators] synonym: "regulation of arthropod blood cell differentiation" EXACT [] xref: GO:0045610 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0058112 ! M4K1_HUMAN [Term] id: CCO:P0002425 name: negative regulation of hemocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemocyte differentiation." [GOC:go_curators] synonym: "down regulation of hemocyte differentiation" EXACT [] synonym: "down-regulation of hemocyte differentiation" EXACT [] synonym: "downregulation of hemocyte differentiation" EXACT [] synonym: "inhibition of hemocyte differentiation" NARROW [] synonym: "negative regulation of arthropod blood cell differentiation" EXACT [] xref: GO:0045611 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002424 ! regulation of hemocyte differentiation [Term] id: CCO:P0002426 name: positive regulation of hemocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hemocyte differentiation." [GOC:go_curators] synonym: "activation of hemocyte differentiation" NARROW [] synonym: "positive regulation of arthropod blood cell differentiation" EXACT [] synonym: "stimulation of hemocyte differentiation" NARROW [] synonym: "up regulation of hemocyte differentiation" EXACT [] synonym: "up-regulation of hemocyte differentiation" EXACT [] synonym: "upregulation of hemocyte differentiation" EXACT [] xref: GO:0045612 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002424 ! regulation of hemocyte differentiation [Term] id: CCO:P0002427 name: regulation of plasmatocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of plasmatocyte differentiation." [GOC:go_curators] xref: GO:0045613 is_a: CCO:P0002424 ! regulation of hemocyte differentiation [Term] id: CCO:P0002428 name: negative regulation of plasmatocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasmatocyte differentiation." [GOC:go_curators] synonym: "down regulation of plasmatocyte differentiation" EXACT [] synonym: "down-regulation of plasmatocyte differentiation" EXACT [] synonym: "downregulation of plasmatocyte differentiation" EXACT [] synonym: "inhibition of plasmatocyte differentiation" NARROW [] xref: GO:0045614 is_a: CCO:P0002425 ! negative regulation of hemocyte differentiation is_a: CCO:P0002427 ! regulation of plasmatocyte differentiation [Term] id: CCO:P0002429 name: positive regulation of plasmatocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation." [GOC:go_curators] synonym: "activation of plasmatocyte differentiation" NARROW [] synonym: "stimulation of plasmatocyte differentiation" NARROW [] synonym: "up regulation of plasmatocyte differentiation" EXACT [] synonym: "up-regulation of plasmatocyte differentiation" EXACT [] synonym: "upregulation of plasmatocyte differentiation" EXACT [] xref: GO:0045615 is_a: CCO:P0002426 ! positive regulation of hemocyte differentiation is_a: CCO:P0002427 ! regulation of plasmatocyte differentiation [Term] id: CCO:P0002430 name: regulation of keratinocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of keratinocyte differentiation." [GOC:go_curators] xref: GO:0045616 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0058057 ! AQP3_HUMAN [Term] id: CCO:P0002431 name: negative regulation of keratinocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte differentiation." [GOC:go_curators] synonym: "down regulation of keratinocyte differentiation" EXACT [] synonym: "down-regulation of keratinocyte differentiation" EXACT [] synonym: "downregulation of keratinocyte differentiation" EXACT [] synonym: "inhibition of keratinocyte differentiation" NARROW [] xref: GO:0045617 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002430 ! regulation of keratinocyte differentiation relationship: has_participant CCO:B0036793 ! HXA7_HUMAN [Term] id: CCO:P0002432 name: positive regulation of keratinocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation." [GOC:go_curators] synonym: "activation of keratinocyte differentiation" NARROW [] synonym: "stimulation of keratinocyte differentiation" NARROW [] synonym: "up regulation of keratinocyte differentiation" EXACT [] synonym: "up-regulation of keratinocyte differentiation" EXACT [] synonym: "upregulation of keratinocyte differentiation" EXACT [] xref: GO:0045618 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002430 ! regulation of keratinocyte differentiation relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0058987 ! IL20_HUMAN [Term] id: CCO:P0002433 name: regulation of lymphocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] xref: GO:0045619 is_a: CCO:P0002409 ! regulation of cell differentiation is_a: CCO:P0003065 ! regulation of lymphocyte activation [Term] id: CCO:P0002434 name: negative regulation of lymphocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] synonym: "down regulation of lymphocyte differentiation" EXACT [] synonym: "down-regulation of lymphocyte differentiation" EXACT [] synonym: "downregulation of lymphocyte differentiation" EXACT [] synonym: "inhibition of lymphocyte differentiation" NARROW [] xref: GO:0045620 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002433 ! regulation of lymphocyte differentiation is_a: CCO:P0003066 ! negative regulation of lymphocyte activation [Term] id: CCO:P0002435 name: positive regulation of lymphocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] synonym: "activation of lymphocyte differentiation" NARROW [] synonym: "stimulation of lymphocyte differentiation" NARROW [] synonym: "up regulation of lymphocyte differentiation" EXACT [] synonym: "up-regulation of lymphocyte differentiation" EXACT [] synonym: "upregulation of lymphocyte differentiation" EXACT [] xref: GO:0045621 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002433 ! regulation of lymphocyte differentiation is_a: CCO:P0003067 ! positive regulation of lymphocyte activation [Term] id: CCO:P0002436 name: regulation of T-helper cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T-helper cell differentiation." [GOC:go_curators] xref: GO:0045622 is_a: CCO:P0002197 ! regulation of CD4-positive, alpha beta T cell differentiation relationship: has_participant CCO:B0056056 ! IRF4_HUMAN [Term] id: CCO:P0002437 name: negative regulation of T-helper cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper cell differentiation." [GOC:go_curators] synonym: "down regulation of T-helper cell differentiation" EXACT [] synonym: "down-regulation of T-helper cell differentiation" EXACT [] synonym: "downregulation of T-helper cell differentiation" EXACT [] synonym: "inhibition of T-helper cell differentiation" NARROW [] xref: GO:0045623 is_a: CCO:P0002198 ! negative regulation of CD4-positive, alpha beta T cell differentiation is_a: CCO:P0002436 ! regulation of T-helper cell differentiation [Term] id: CCO:P0002438 name: positive regulation of T-helper cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation." [GOC:go_curators] synonym: "activation of T-helper cell differentiation" NARROW [] synonym: "stimulation of T-helper cell differentiation" NARROW [] synonym: "up regulation of T-helper cell differentiation" EXACT [] synonym: "up-regulation of T-helper cell differentiation" EXACT [] synonym: "upregulation of T-helper cell differentiation" EXACT [] xref: GO:0045624 is_a: CCO:P0002199 ! positive regulation of CD4-positive, alpha beta T cell differentiation is_a: CCO:P0002436 ! regulation of T-helper cell differentiation [Term] id: CCO:P0002439 name: regulation of T-helper 1 cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation." [GOC:go_curators] xref: GO:0045625 is_a: CCO:P0002436 ! regulation of T-helper cell differentiation relationship: has_participant CCO:B0057596 ! IL27A_HUMAN [Term] id: CCO:P0002440 name: negative regulation of T-helper 1 cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell differentiation." [GOC:go_curators] synonym: "down regulation of T-helper 1 cell differentiation" EXACT [] synonym: "down-regulation of T-helper 1 cell differentiation" EXACT [] synonym: "downregulation of T-helper 1 cell differentiation" EXACT [] synonym: "inhibition of T-helper 1 cell differentiation" NARROW [] xref: GO:0045626 is_a: CCO:P0002437 ! negative regulation of T-helper cell differentiation is_a: CCO:P0002439 ! regulation of T-helper 1 cell differentiation [Term] id: CCO:P0002441 name: positive regulation of T-helper 1 cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation." [GOC:go_curators] synonym: "activation of T-helper 1 cell differentiation" NARROW [] synonym: "stimulation of T-helper 1 cell differentiation" NARROW [] synonym: "up regulation of T-helper 1 cell differentiation" EXACT [] synonym: "up-regulation of T-helper 1 cell differentiation" EXACT [] synonym: "upregulation of T-helper 1 cell differentiation" EXACT [] xref: GO:0045627 is_a: CCO:P0002438 ! positive regulation of T-helper cell differentiation is_a: CCO:P0002439 ! regulation of T-helper 1 cell differentiation relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN relationship: has_participant CCO:B0055268 ! CD80_HUMAN [Term] id: CCO:P0002442 name: regulation of T-helper 2 cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation." [GOC:go_curators] xref: GO:0045628 is_a: CCO:P0002436 ! regulation of T-helper cell differentiation [Term] id: CCO:P0002443 name: negative regulation of T-helper 2 cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell differentiation." [GOC:go_curators] synonym: "down regulation of T-helper 2 cell differentiation" EXACT [] synonym: "down-regulation of T-helper 2 cell differentiation" EXACT [] synonym: "downregulation of T-helper 2 cell differentiation" EXACT [] synonym: "inhibition of T-helper 2 cell differentiation" NARROW [] xref: GO:0045629 is_a: CCO:P0002437 ! negative regulation of T-helper cell differentiation is_a: CCO:P0002442 ! regulation of T-helper 2 cell differentiation relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0054608 ! SOCS5_HUMAN [Term] id: CCO:P0002444 name: positive regulation of T-helper 2 cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation." [GOC:go_curators] synonym: "activation of T-helper 2 cell differentiation" NARROW [] synonym: "stimulation of T-helper 2 cell differentiation" NARROW [] synonym: "up regulation of T-helper 2 cell differentiation" EXACT [] synonym: "up-regulation of T-helper 2 cell differentiation" EXACT [] synonym: "upregulation of T-helper 2 cell differentiation" EXACT [] xref: GO:0045630 is_a: CCO:P0002438 ! positive regulation of T-helper cell differentiation is_a: CCO:P0002442 ! regulation of T-helper 2 cell differentiation relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0055346 ! CD86_HUMAN [Term] id: CCO:P0002445 name: regulation of mechanoreceptor differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation." [GOC:go_curators] xref: GO:0045631 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002446 name: negative regulation of mechanoreceptor differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mechanoreceptor differentiation." [GOC:go_curators] synonym: "down regulation of mechanoreceptor differentiation" EXACT [] synonym: "down-regulation of mechanoreceptor differentiation" EXACT [] synonym: "downregulation of mechanoreceptor differentiation" EXACT [] synonym: "inhibition of mechanoreceptor differentiation" NARROW [] xref: GO:0045632 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002445 ! regulation of mechanoreceptor differentiation [Term] id: CCO:P0002447 name: positive regulation of mechanoreceptor differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation." [GOC:go_curators] synonym: "activation of mechanoreceptor differentiation" NARROW [] synonym: "stimulation of mechanoreceptor differentiation" NARROW [] synonym: "up regulation of mechanoreceptor differentiation" EXACT [] synonym: "up-regulation of mechanoreceptor differentiation" EXACT [] synonym: "upregulation of mechanoreceptor differentiation" EXACT [] xref: GO:0045633 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002445 ! regulation of mechanoreceptor differentiation [Term] id: CCO:P0002448 name: regulation of melanocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of melanocyte differentiation." [GOC:go_curators] synonym: "regulation of melanophore differentiation" EXACT [] xref: GO:0045634 is_a: CCO:P0002990 ! regulation of pigment cell differentiation relationship: has_participant CCO:B0030251 ! GNA11_HUMAN [Term] id: CCO:P0002449 name: negative regulation of melanocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of melanocyte differentiation." [GOC:go_curators] synonym: "down regulation of melanocyte differentiation" EXACT [] synonym: "down-regulation of melanocyte differentiation" EXACT [] synonym: "downregulation of melanocyte differentiation" EXACT [] synonym: "inhibition of melanocyte differentiation" NARROW [] synonym: "negative regulation of melanophore differentiation" EXACT [] xref: GO:0045635 is_a: CCO:P0002448 ! regulation of melanocyte differentiation is_a: CCO:P0002995 ! negative regulation of pigment cell differentiation [Term] id: CCO:P0002450 name: positive regulation of melanocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of melanocyte differentiation." [GOC:go_curators] synonym: "activation of melanocyte differentiation" NARROW [] synonym: "positive regulation of melanophore differentiation" EXACT [] synonym: "stimulation of melanocyte differentiation" NARROW [] synonym: "up regulation of melanocyte differentiation" EXACT [] synonym: "up-regulation of melanocyte differentiation" EXACT [] synonym: "upregulation of melanocyte differentiation" EXACT [] xref: GO:0045636 is_a: CCO:P0002448 ! regulation of melanocyte differentiation is_a: CCO:P0002996 ! positive regulation of pigment cell differentiation [Term] id: CCO:P0002451 name: regulation of myeloid cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] xref: GO:0045637 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0017945 ! PURB_HUMAN [Term] id: CCO:P0002452 name: negative regulation of myeloid cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "down regulation of myeloid cell differentiation" EXACT [] synonym: "down-regulation of myeloid cell differentiation" EXACT [] synonym: "downregulation of myeloid cell differentiation" EXACT [] synonym: "inhibition of myeloid cell differentiation" NARROW [] xref: GO:0045638 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002451 ! regulation of myeloid cell differentiation relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: has_participant CCO:B0026499 ! TTP_HUMAN relationship: has_participant CCO:B0050279 ! HMGB3_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN [Term] id: CCO:P0002453 name: positive regulation of myeloid cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "activation of myeloid cell differentiation" NARROW [] synonym: "stimulation of myeloid cell differentiation" NARROW [] synonym: "up regulation of myeloid cell differentiation" EXACT [] synonym: "up-regulation of myeloid cell differentiation" EXACT [] synonym: "upregulation of myeloid cell differentiation" EXACT [] xref: GO:0045639 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002451 ! regulation of myeloid cell differentiation relationship: has_participant CCO:B0028290 ! JAG1_HUMAN relationship: has_participant CCO:B0055333 ! LEP_HUMAN [Term] id: CCO:P0002454 name: regulation of basophil differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of basophil differentiation." [GOC:go_curators] xref: GO:0045640 is_a: CCO:P0001339 ! regulation of granulocyte differentiation [Term] id: CCO:P0002455 name: negative regulation of basophil differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of basophil differentiation." [GOC:go_curators] synonym: "down regulation of basophil differentiation" EXACT [] synonym: "down-regulation of basophil differentiation" EXACT [] synonym: "downregulation of basophil differentiation" EXACT [] synonym: "inhibition of basophil differentiation" NARROW [] xref: GO:0045641 is_a: CCO:P0001340 ! negative regulation of granulocyte differentiation is_a: CCO:P0002454 ! regulation of basophil differentiation [Term] id: CCO:P0002456 name: positive regulation of basophil differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of basophil differentiation." [GOC:go_curators] synonym: "activation of basophil differentiation" NARROW [] synonym: "stimulation of basophil differentiation" NARROW [] synonym: "up regulation of basophil differentiation" EXACT [] synonym: "up-regulation of basophil differentiation" EXACT [] synonym: "upregulation of basophil differentiation" EXACT [] xref: GO:0045642 is_a: CCO:P0001341 ! positive regulation of granulocyte differentiation is_a: CCO:P0002454 ! regulation of basophil differentiation [Term] id: CCO:P0002457 name: regulation of eosinophil differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of eosinophil differentiation." [GOC:go_curators] xref: GO:0045643 is_a: CCO:P0001339 ! regulation of granulocyte differentiation [Term] id: CCO:P0002458 name: negative regulation of eosinophil differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil differentiation." [GOC:go_curators] synonym: "down regulation of eosinophil differentiation" EXACT [] synonym: "down-regulation of eosinophil differentiation" EXACT [] synonym: "downregulation of eosinophil differentiation" EXACT [] synonym: "inhibition of eosinophil differentiation" NARROW [] xref: GO:0045644 is_a: CCO:P0001340 ! negative regulation of granulocyte differentiation is_a: CCO:P0002457 ! regulation of eosinophil differentiation [Term] id: CCO:P0002459 name: positive regulation of eosinophil differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of eosinophil differentiation." [GOC:go_curators] synonym: "activation of eosinophil differentiation" NARROW [] synonym: "stimulation of eosinophil differentiation" NARROW [] synonym: "up regulation of eosinophil differentiation" EXACT [] synonym: "up-regulation of eosinophil differentiation" EXACT [] synonym: "upregulation of eosinophil differentiation" EXACT [] xref: GO:0045645 is_a: CCO:P0001341 ! positive regulation of granulocyte differentiation is_a: CCO:P0002457 ! regulation of eosinophil differentiation [Term] id: CCO:P0002460 name: regulation of erythrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] xref: GO:0045646 is_a: CCO:P0002451 ! regulation of myeloid cell differentiation relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0055095 ! SPI1_HUMAN [Term] id: CCO:P0002461 name: negative regulation of erythrocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "down regulation of erythrocyte differentiation" EXACT [] synonym: "down-regulation of erythrocyte differentiation" EXACT [] synonym: "downregulation of erythrocyte differentiation" EXACT [] synonym: "inhibition of erythrocyte differentiation" NARROW [] xref: GO:0045647 is_a: CCO:P0002452 ! negative regulation of myeloid cell differentiation is_a: CCO:P0002460 ! regulation of erythrocyte differentiation relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0033733 ! MAFB_HUMAN relationship: has_participant CCO:B0057244 ! LDB1_HUMAN [Term] id: CCO:P0002462 name: positive regulation of erythrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "activation of erythrocyte differentiation" NARROW [] synonym: "stimulation of erythrocyte differentiation" NARROW [] synonym: "up regulation of erythrocyte differentiation" EXACT [] synonym: "up-regulation of erythrocyte differentiation" EXACT [] synonym: "upregulation of erythrocyte differentiation" EXACT [] xref: GO:0045648 is_a: CCO:P0002453 ! positive regulation of myeloid cell differentiation is_a: CCO:P0002460 ! regulation of erythrocyte differentiation relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001597 ! ACV1B_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0030313 ! ETS1_HUMAN relationship: has_participant CCO:B0050345 ! FOXO3_HUMAN [Term] id: CCO:P0002463 name: regulation of macrophage differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of macrophage differentiation." [GOC:go_curators] xref: GO:0045649 is_a: CCO:P0000575 ! regulation of myeloid leukocyte differentiation [Term] id: CCO:P0002464 name: negative regulation of macrophage differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage differentiation." [GOC:go_curators] synonym: "down regulation of macrophage differentiation" EXACT [] synonym: "down-regulation of macrophage differentiation" EXACT [] synonym: "downregulation of macrophage differentiation" EXACT [] synonym: "inhibition of macrophage differentiation" NARROW [] xref: GO:0045650 is_a: CCO:P0000576 ! negative regulation of myeloid leukocyte differentiation is_a: CCO:P0002463 ! regulation of macrophage differentiation relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN [Term] id: CCO:P0002465 name: positive regulation of macrophage differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of macrophage differentiation." [GOC:go_curators] synonym: "activation of macrophage differentiation" NARROW [] synonym: "stimulation of macrophage differentiation" NARROW [] synonym: "up regulation of macrophage differentiation" EXACT [] synonym: "up-regulation of macrophage differentiation" EXACT [] synonym: "upregulation of macrophage differentiation" EXACT [] xref: GO:0045651 is_a: CCO:P0000577 ! positive regulation of myeloid leukocyte differentiation is_a: CCO:P0002463 ! regulation of macrophage differentiation relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0006149 ! ID2_HUMAN relationship: has_participant CCO:B0054907 ! CALCA_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN [Term] id: CCO:P0002466 name: regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] xref: GO:0045652 is_a: CCO:P0002451 ! regulation of myeloid cell differentiation [Term] id: CCO:P0002467 name: negative regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "down regulation of megakaryocyte differentiation" EXACT [] synonym: "down-regulation of megakaryocyte differentiation" EXACT [] synonym: "downregulation of megakaryocyte differentiation" EXACT [] synonym: "inhibition of megakaryocyte differentiation" NARROW [] xref: GO:0045653 is_a: CCO:P0002452 ! negative regulation of myeloid cell differentiation is_a: CCO:P0002466 ! regulation of megakaryocyte differentiation relationship: has_participant CCO:B0041664 ! PLF4_HUMAN [Term] id: CCO:P0002468 name: positive regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "activation of megakaryocyte differentiation" NARROW [] synonym: "stimulation of megakaryocyte differentiation" NARROW [] synonym: "up regulation of megakaryocyte differentiation" EXACT [] synonym: "up-regulation of megakaryocyte differentiation" EXACT [] synonym: "upregulation of megakaryocyte differentiation" EXACT [] xref: GO:0045654 is_a: CCO:P0002453 ! positive regulation of myeloid cell differentiation is_a: CCO:P0002466 ! regulation of megakaryocyte differentiation relationship: has_participant CCO:B0051620 ! ADSV_HUMAN [Term] id: CCO:P0002469 name: regulation of monocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of monocyte differentiation." [GOC:go_curators] xref: GO:0045655 is_a: CCO:P0000575 ! regulation of myeloid leukocyte differentiation [Term] id: CCO:P0002470 name: negative regulation of monocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of monocyte differentiation." [GOC:go_curators] synonym: "down regulation of monocyte differentiation" EXACT [] synonym: "down-regulation of monocyte differentiation" EXACT [] synonym: "downregulation of monocyte differentiation" EXACT [] synonym: "inhibition of monocyte differentiation" NARROW [] xref: GO:0045656 is_a: CCO:P0000576 ! negative regulation of myeloid leukocyte differentiation is_a: CCO:P0002469 ! regulation of monocyte differentiation [Term] id: CCO:P0002471 name: positive regulation of monocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of monocyte differentiation." [GOC:go_curators] synonym: "activation of monocyte differentiation" NARROW [] synonym: "stimulation of monocyte differentiation" NARROW [] synonym: "up regulation of monocyte differentiation" EXACT [] synonym: "up-regulation of monocyte differentiation" EXACT [] synonym: "upregulation of monocyte differentiation" EXACT [] xref: GO:0045657 is_a: CCO:P0000577 ! positive regulation of myeloid leukocyte differentiation is_a: CCO:P0002469 ! regulation of monocyte differentiation relationship: has_participant CCO:B0059205 ! ACINU_HUMAN [Term] id: CCO:P0002472 name: regulation of neutrophil differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neutrophil differentiation." [GOC:go_curators] xref: GO:0045658 is_a: CCO:P0001339 ! regulation of granulocyte differentiation [Term] id: CCO:P0002473 name: negative regulation of neutrophil differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil differentiation." [GOC:go_curators] synonym: "down regulation of neutrophil differentiation" EXACT [] synonym: "down-regulation of neutrophil differentiation" EXACT [] synonym: "downregulation of neutrophil differentiation" EXACT [] synonym: "inhibition of neutrophil differentiation" NARROW [] xref: GO:0045659 is_a: CCO:P0001340 ! negative regulation of granulocyte differentiation is_a: CCO:P0002472 ! regulation of neutrophil differentiation [Term] id: CCO:P0002474 name: positive regulation of neutrophil differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neutrophil differentiation." [GOC:go_curators] synonym: "activation of neutrophil differentiation" NARROW [] synonym: "stimulation of neutrophil differentiation" NARROW [] synonym: "up regulation of neutrophil differentiation" EXACT [] synonym: "up-regulation of neutrophil differentiation" EXACT [] synonym: "upregulation of neutrophil differentiation" EXACT [] xref: GO:0045660 is_a: CCO:P0001341 ! positive regulation of granulocyte differentiation is_a: CCO:P0002472 ! regulation of neutrophil differentiation [Term] id: CCO:P0002475 name: regulation of myoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] xref: GO:0045661 is_a: CCO:P0003044 ! regulation of muscle cell differentiation [Term] id: CCO:P0002476 name: negative regulation of myoblast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "down regulation of myoblast differentiation" EXACT [] synonym: "down-regulation of myoblast differentiation" EXACT [] synonym: "downregulation of myoblast differentiation" EXACT [] synonym: "inhibition of myoblast differentiation" NARROW [] xref: GO:0045662 is_a: CCO:P0002475 ! regulation of myoblast differentiation is_a: CCO:P0003045 ! negative regulation of muscle cell differentiation relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001516 ! BMP4_HUMAN relationship: has_participant CCO:B0005974 ! NOTC1_HUMAN [Term] id: CCO:P0002477 name: positive regulation of myoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "activation of myoblast differentiation" NARROW [] synonym: "stimulation of myoblast differentiation" NARROW [] synonym: "up regulation of myoblast differentiation" EXACT [] synonym: "up-regulation of myoblast differentiation" EXACT [] synonym: "upregulation of myoblast differentiation" EXACT [] xref: GO:0045663 is_a: CCO:P0002475 ! regulation of myoblast differentiation is_a: CCO:P0003046 ! positive regulation of muscle cell differentiation relationship: has_participant CCO:B0006259 ! BOC_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN relationship: has_participant CCO:B0055615 ! BTG1_HUMAN [Term] id: CCO:P0002478 name: regulation of neuron differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators] xref: GO:0045664 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0001802 ! CD5R1_HUMAN relationship: has_participant CCO:B0002044 ! CK5P3_HUMAN relationship: has_participant CCO:B0002062 ! CK5P1_HUMAN relationship: has_participant CCO:B0005489 ! 1433G_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0006178 ! CK5P2_HUMAN relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0055046 ! TIMP2_HUMAN relationship: has_participant CCO:B0056069 ! SIX1_HUMAN relationship: has_participant CCO:B0057446 ! NLGN1_HUMAN relationship: has_participant CCO:B0058108 ! ATOH1_HUMAN [Term] id: CCO:P0002479 name: negative regulation of neuron differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "down regulation of neuron differentiation" EXACT [] synonym: "down-regulation of neuron differentiation" EXACT [] synonym: "downregulation of neuron differentiation" EXACT [] synonym: "inhibition of neuron differentiation" NARROW [] xref: GO:0045665 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002478 ! regulation of neuron differentiation relationship: has_participant CCO:B0016149 ! PRP19_HUMAN relationship: has_participant CCO:B0017820 ! NOTC3_HUMAN relationship: has_participant CCO:B0022226 ! ID4_HUMAN relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0054512 ! TLX3_HUMAN relationship: has_participant CCO:B0055507 ! LBX1_HUMAN relationship: has_participant CCO:B0055986 ! HES1_HUMAN relationship: has_participant CCO:B0056603 ! HES5_HUMAN relationship: has_participant CCO:B0057298 ! DTX1_HUMAN relationship: has_participant CCO:B0057312 ! MIB1_HUMAN relationship: has_participant CCO:B0057365 ! CNTN4_HUMAN [Term] id: CCO:P0002480 name: positive regulation of neuron differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "activation of neuron differentiation" NARROW [] synonym: "stimulation of neuron differentiation" NARROW [] synonym: "up regulation of neuron differentiation" EXACT [] synonym: "up-regulation of neuron differentiation" EXACT [] synonym: "upregulation of neuron differentiation" EXACT [] xref: GO:0045666 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002478 ! regulation of neuron differentiation relationship: has_participant CCO:B0015672 ! NRCAM_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056226 ! VWC2_HUMAN [Term] id: CCO:P0002481 name: regulation of osteoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of osteoblast differentiation." [GOC:go_curators] xref: GO:0045667 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002482 name: negative regulation of osteoblast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of osteoblast differentiation." [GOC:go_curators] synonym: "down regulation of osteoblast differentiation" EXACT [] synonym: "down-regulation of osteoblast differentiation" EXACT [] synonym: "downregulation of osteoblast differentiation" EXACT [] synonym: "inhibition of osteoblast differentiation" NARROW [] xref: GO:0045668 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002481 ! regulation of osteoblast differentiation relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0025823 ! TOB1_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0055609 ! OSTN_HUMAN relationship: has_participant CCO:B0057994 ! TWST2_HUMAN relationship: has_participant CCO:B0058643 ! TWSG1_HUMAN [Term] id: CCO:P0002483 name: positive regulation of osteoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of osteoblast differentiation." [GOC:go_curators] synonym: "activation of osteoblast differentiation" NARROW [] synonym: "stimulation of osteoblast differentiation" NARROW [] synonym: "up regulation of osteoblast differentiation" EXACT [] synonym: "up-regulation of osteoblast differentiation" EXACT [] synonym: "upregulation of osteoblast differentiation" EXACT [] xref: GO:0045669 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002481 ! regulation of osteoblast differentiation relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0001516 ! BMP4_HUMAN relationship: has_participant CCO:B0001531 ! BMP7_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0001767 ! BMPR2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005437 ! BMR1A_HUMAN relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN relationship: has_participant CCO:B0020371 ! BMR1B_HUMAN relationship: has_participant CCO:B0037989 ! DLX5_HUMAN relationship: has_participant CCO:B0042130 ! BMP6_HUMAN relationship: has_participant CCO:B0055551 ! WNT7B_HUMAN relationship: has_participant CCO:B0055940 ! AVR2B_HUMAN [Term] id: CCO:P0002484 name: regulation of osteoclast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of osteoclast differentiation." [GOC:go_curators] xref: GO:0045670 is_a: CCO:P0000575 ! regulation of myeloid leukocyte differentiation relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0054878 ! OSTC_HUMAN [Term] id: CCO:P0002485 name: negative regulation of osteoclast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation." [GOC:go_curators] synonym: "down regulation of osteoclast differentiation" EXACT [] synonym: "down-regulation of osteoclast differentiation" EXACT [] synonym: "downregulation of osteoclast differentiation" EXACT [] synonym: "inhibition of osteoclast differentiation" NARROW [] xref: GO:0045671 is_a: CCO:P0000576 ! negative regulation of myeloid leukocyte differentiation is_a: CCO:P0002484 ! regulation of osteoclast differentiation relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0022071 ! TLR4_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0054907 ! CALCA_HUMAN relationship: has_participant CCO:B0056152 ! CART_HUMAN [Term] id: CCO:P0002486 name: positive regulation of osteoclast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of osteoclast differentiation." [GOC:go_curators] synonym: "activation of osteoclast differentiation" NARROW [] synonym: "stimulation of osteoclast differentiation" NARROW [] synonym: "up regulation of osteoclast differentiation" EXACT [] synonym: "up-regulation of osteoclast differentiation" EXACT [] synonym: "upregulation of osteoclast differentiation" EXACT [] xref: GO:0045672 is_a: CCO:P0000577 ! positive regulation of myeloid leukocyte differentiation is_a: CCO:P0002484 ! regulation of osteoclast differentiation relationship: has_participant CCO:B0054375 ! TNF11_HUMAN [Term] id: CCO:P0002487 name: regulation of R7 cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of R7 differentiation." [GOC:go_curators] xref: GO:0045676 is_a: CCO:P0002695 ! regulation of photoreceptor cell differentiation [Term] id: CCO:P0002488 name: negative regulation of R7 cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of R7cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of R7 differentiation" EXACT [] synonym: "down-regulation of R7 differentiation" EXACT [] synonym: "downregulation of R7 differentiation" EXACT [] synonym: "inhibition of R7 differentiation" NARROW [] synonym: "negative regulation of R7 differentiation" EXACT [GOC:dph, GOC:tb] xref: GO:0045677 is_a: CCO:P0002487 ! regulation of R7 cell differentiation is_a: CCO:P0002696 ! negative regulation of photoreceptor cell differentiation [Term] id: CCO:P0002489 name: positive regulation of R7 cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of R7 cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of R7 differentiation" NARROW [] synonym: "positive regulation of R7 differentiation" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of R7 differentiation" NARROW [] synonym: "up regulation of R7 differentiation" EXACT [] synonym: "up-regulation of R7 differentiation" EXACT [] synonym: "upregulation of R7 differentiation" EXACT [] xref: GO:0045678 is_a: CCO:P0002487 ! regulation of R7 cell differentiation is_a: CCO:P0002697 ! positive regulation of photoreceptor cell differentiation [Term] id: CCO:P0002490 name: regulation of R8 cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of R8 differentiation." [GOC:go_curators] xref: GO:0045679 is_a: CCO:P0002695 ! regulation of photoreceptor cell differentiation [Term] id: CCO:P0002491 name: negative regulation of R8 cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of R8 cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of R8 differentiation" EXACT [] synonym: "down-regulation of R8 differentiation" EXACT [] synonym: "downregulation of R8 differentiation" EXACT [] synonym: "inhibition of R8 differentiation" NARROW [] synonym: "negative regulation of R8 differentiation" EXACT [GOC:dph, GOC:tb] xref: GO:0045680 is_a: CCO:P0002490 ! regulation of R8 cell differentiation is_a: CCO:P0002696 ! negative regulation of photoreceptor cell differentiation [Term] id: CCO:P0002492 name: positive regulation of R8 cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of R8 cell differentiation." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of R8 differentiation" NARROW [] synonym: "positive regulation of R8 differentiation" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of R8 differentiation" NARROW [] synonym: "up regulation of R8 differentiation" EXACT [] synonym: "up-regulation of R8 differentiation" EXACT [] synonym: "upregulation of R8 differentiation" EXACT [] xref: GO:0045681 is_a: CCO:P0002490 ! regulation of R8 cell differentiation is_a: CCO:P0002697 ! positive regulation of photoreceptor cell differentiation [Term] id: CCO:P0002493 name: regulation of glial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "regulation of glia cell differentiation" EXACT [] synonym: "regulation of neuroglia differentiation" EXACT [] xref: GO:0045685 is_a: CCO:P0001059 ! regulation of gliogenesis is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:P0002494 name: negative regulation of glial cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "down regulation of glial cell differentiation" EXACT [] synonym: "down-regulation of glial cell differentiation" EXACT [] synonym: "downregulation of glial cell differentiation" EXACT [] synonym: "inhibition of glial cell differentiation" NARROW [] synonym: "negative regulation of glia cell differentiation" EXACT [] synonym: "negative regulation of neuroglia differentiation" EXACT [] xref: GO:0045686 is_a: CCO:P0001060 ! negative regulation of gliogenesis is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002493 ! regulation of glial cell differentiation relationship: has_participant CCO:B0037991 ! NKX61_HUMAN [Term] id: CCO:P0002495 name: positive regulation of glial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "activation of glial cell differentiation" NARROW [] synonym: "positive regulation of glia cell differentiation" EXACT [] synonym: "positive regulation of neuroglia differentiation" EXACT [] synonym: "stimulation of glial cell differentiation" NARROW [] synonym: "up regulation of glial cell differentiation" EXACT [] synonym: "up-regulation of glial cell differentiation" EXACT [] synonym: "upregulation of glial cell differentiation" EXACT [] xref: GO:0045687 is_a: CCO:P0001061 ! positive regulation of gliogenesis is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002493 ! regulation of glial cell differentiation relationship: has_participant CCO:B0037991 ! NKX61_HUMAN relationship: has_participant CCO:B0055124 ! NTF3_HUMAN [Term] id: CCO:P0002496 name: regulation of antipodal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of antipodal cell differentiation." [GOC:go_curators, GOC:mtg_plant] xref: GO:0045688 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002497 name: negative regulation of antipodal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of antipodal cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "down regulation of antipodal cell differentiation" EXACT [] synonym: "down-regulation of antipodal cell differentiation" EXACT [] synonym: "downregulation of antipodal cell differentiation" EXACT [] synonym: "inhibition of antipodal cell differentiation" NARROW [] xref: GO:0045689 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002496 ! regulation of antipodal cell differentiation [Term] id: CCO:P0002498 name: positive regulation of antipodal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "activation of antipodal cell differentiation" NARROW [] synonym: "stimulation of antipodal cell differentiation" NARROW [] synonym: "up regulation of antipodal cell differentiation" EXACT [] synonym: "up-regulation of antipodal cell differentiation" EXACT [] synonym: "upregulation of antipodal cell differentiation" EXACT [] xref: GO:0045690 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002496 ! regulation of antipodal cell differentiation [Term] id: CCO:P0002499 name: regulation of embryo sac central cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "regulation of female gametophyte central cell differentiation" EXACT [] xref: GO:0045691 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002500 name: negative regulation of embryo sac central cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryo sac central cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "down regulation of female gametophyte central cell differentiation" EXACT [] synonym: "down-regulation of female gametophyte central cell differentiation" EXACT [] synonym: "downregulation of female gametophyte central cell differentiation" EXACT [] synonym: "inhibition of female gametophyte central cell differentiation" NARROW [] synonym: "negative regulation of female gametophyte central cell differentiation" EXACT [] xref: GO:0045692 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002499 ! regulation of embryo sac central cell differentiation [Term] id: CCO:P0002501 name: positive regulation of embryo sac central cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "activation of female gametophyte central cell differentiation" NARROW [] synonym: "positive regulation of female gametophyte central cell differentiation" EXACT [] synonym: "stimulation of female gametophyte central cell differentiation" NARROW [] synonym: "up regulation of female gametophyte central cell differentiation" EXACT [] synonym: "up-regulation of female gametophyte central cell differentiation" EXACT [] synonym: "upregulation of female gametophyte central cell differentiation" EXACT [] xref: GO:0045693 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002499 ! regulation of embryo sac central cell differentiation [Term] id: CCO:P0002502 name: regulation of embryo sac egg cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "regulation of female gametophyte egg cell differentiation" EXACT [] xref: GO:0045694 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002503 name: negative regulation of embryo sac egg cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryo sac egg cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "down regulation of female gametophyte egg cell differentiation" EXACT [] synonym: "down-regulation of female gametophyte egg cell differentiation" EXACT [] synonym: "downregulation of female gametophyte egg cell differentiation" EXACT [] synonym: "inhibition of female gametophyte egg cell differentiation" NARROW [] synonym: "negative regulation of female gametophyte egg cell differentiation" EXACT [] xref: GO:0045695 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002502 ! regulation of embryo sac egg cell differentiation [Term] id: CCO:P0002504 name: positive regulation of embryo sac egg cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation." [GOC:go_curators, GOC:mtg_plant] synonym: "activation of female gametophyte egg cell differentiation" NARROW [] synonym: "positive regulation of female gametophyte egg cell differentiation" EXACT [] synonym: "stimulation of female gametophyte egg cell differentiation" NARROW [] synonym: "up regulation of female gametophyte egg cell differentiation" EXACT [] synonym: "up-regulation of female gametophyte egg cell differentiation" EXACT [] synonym: "upregulation of female gametophyte egg cell differentiation" EXACT [] xref: GO:0045696 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002502 ! regulation of embryo sac egg cell differentiation [Term] id: CCO:P0002505 name: regulation of synergid differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synergid cell differentiation." [GOC:go_curators] synonym: "regulation of synergid cell differentiation" EXACT [] xref: GO:0045697 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002506 name: negative regulation of synergid differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synergid cell differentiation." [GOC:go_curators] synonym: "down regulation of synergid differentiation" EXACT [] synonym: "down-regulation of synergid differentiation" EXACT [] synonym: "downregulation of synergid differentiation" EXACT [] synonym: "inhibition of synergid differentiation" NARROW [] synonym: "negative regulation of synergid cell differentiation" EXACT [] xref: GO:0045698 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002505 ! regulation of synergid differentiation [Term] id: CCO:P0002507 name: positive regulation of synergid differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synergid cell differentiation." [GOC:go_curators] synonym: "activation of synergid differentiation" NARROW [] synonym: "positive regulation of synergid cell differentiation" EXACT [] synonym: "stimulation of synergid differentiation" NARROW [] synonym: "up regulation of synergid differentiation" EXACT [] synonym: "up-regulation of synergid differentiation" EXACT [] synonym: "upregulation of synergid differentiation" EXACT [] xref: GO:0045699 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002505 ! regulation of synergid differentiation [Term] id: CCO:P0002508 name: regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] xref: GO:0045700 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002509 name: negative regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "down regulation of spermatid nuclear differentiation" EXACT [] synonym: "down-regulation of spermatid nuclear differentiation" EXACT [] synonym: "downregulation of spermatid nuclear differentiation" EXACT [] synonym: "inhibition of spermatid nuclear differentiation" NARROW [] xref: GO:0045701 is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002508 ! regulation of spermatid nuclear differentiation [Term] id: CCO:P0002510 name: positive regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "activation of spermatid nuclear differentiation" NARROW [] synonym: "stimulation of spermatid nuclear differentiation" NARROW [] synonym: "up regulation of spermatid nuclear differentiation" EXACT [] synonym: "up-regulation of spermatid nuclear differentiation" EXACT [] synonym: "upregulation of spermatid nuclear differentiation" EXACT [] xref: GO:0045702 is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002508 ! regulation of spermatid nuclear differentiation [Term] id: CCO:P0002511 name: regulation of low-density lipoprotein receptor biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors." [GOC:go_curators] synonym: "regulation of LDLr biosynthesis" EXACT [] synonym: "regulation of LDLr biosynthetic process" EXACT [] synonym: "regulation of low-density lipoprotein receptor anabolism" EXACT [] synonym: "regulation of low-density lipoprotein receptor biosynthesis" EXACT [] synonym: "regulation of low-density lipoprotein receptor formation" EXACT [] synonym: "regulation of low-density lipoprotein receptor synthesis" EXACT [] xref: GO:0045714 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0002512 name: negative regulation of low-density lipoprotein receptor biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors." [GOC:go_curators] synonym: "down regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] synonym: "down-regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] synonym: "downregulation of low-density lipoprotein receptor biosynthetic process" EXACT [] synonym: "inhibition of low-density lipoprotein receptor biosynthetic process" NARROW [] synonym: "negative regulation of low-density lipoprotein receptor anabolism" EXACT [] synonym: "negative regulation of low-density lipoprotein receptor biosynthesis" EXACT [] synonym: "negative regulation of low-density lipoprotein receptor formation" EXACT [] synonym: "negative regulation of low-density lipoprotein receptor synthesis" EXACT [] xref: GO:0045715 is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0002511 ! regulation of low-density lipoprotein receptor biosynthetic process [Term] id: CCO:P0002513 name: positive regulation of low-density lipoprotein receptor biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors." [GOC:go_curators] synonym: "activation of low-density lipoprotein receptor biosynthetic process" NARROW [] synonym: "positive regulation of low-density lipoprotein receptor anabolism" EXACT [] synonym: "positive regulation of low-density lipoprotein receptor biosynthesis" EXACT [] synonym: "positive regulation of low-density lipoprotein receptor formation" EXACT [] synonym: "positive regulation of low-density lipoprotein receptor synthesis" EXACT [] synonym: "stimulation of low-density lipoprotein receptor biosynthetic process" NARROW [] synonym: "up regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] synonym: "up-regulation of low-density lipoprotein receptor biosynthetic process" EXACT [] synonym: "upregulation of low-density lipoprotein receptor biosynthetic process" EXACT [] xref: GO:0045716 is_a: CCO:P0002511 ! regulation of low-density lipoprotein receptor biosynthetic process is_a: CCO:P0002524 ! positive regulation of translation relationship: has_participant CCO:B0055838 ! SCAP_HUMAN [Term] id: CCO:P0002514 name: negative regulation of fatty acid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of fatty acid biosynthetic process" EXACT [] synonym: "down-regulation of fatty acid biosynthetic process" EXACT [] synonym: "downregulation of fatty acid biosynthetic process" EXACT [] synonym: "inhibition of fatty acid biosynthetic process" NARROW [] synonym: "negative regulation of fatty acid anabolism" EXACT [] synonym: "negative regulation of fatty acid biosynthesis" EXACT [] synonym: "negative regulation of fatty acid formation" EXACT [] synonym: "negative regulation of fatty acid synthesis" EXACT [] xref: GO:0045717 is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0002055 ! regulation of fatty acid biosynthetic process is_a: CCO:P0002615 ! negative regulation of fatty acid metabolic process relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0054864 ! APOC3_HUMAN [Term] id: CCO:P0002515 name: negative regulation of flagellum biogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the formation of a flagellum." [GOC:go_curators] synonym: "down regulation of flagellum biogenesis" EXACT [] synonym: "down-regulation of flagellum biogenesis" EXACT [] synonym: "downregulation of flagellum biogenesis" EXACT [] synonym: "inhibition of flagellum biogenesis" NARROW [] synonym: "negative regulation of flagella biogenesis" EXACT [] xref: GO:0045718 is_a: CCO:P0001242 ! regulation of flagellum biogenesis is_a: CCO:P0001422 ! negative regulation of cell projection organization and biogenesis [Term] id: CCO:P0002516 name: negative regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of glycogen biosynthetic process" EXACT [] synonym: "down-regulation of glycogen biosynthetic process" EXACT [] synonym: "downregulation of glycogen biosynthetic process" EXACT [] synonym: "inhibition of glycogen biosynthetic process" NARROW [] synonym: "negative regulation of glycogen anabolism" EXACT [] synonym: "negative regulation of glycogen biosynthesis" EXACT [] synonym: "negative regulation of glycogen formation" EXACT [] synonym: "negative regulation of glycogen synthesis" EXACT [] xref: GO:0045719 is_a: CCO:P0000621 ! regulation of glycogen biosynthetic process is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process relationship: has_participant CCO:B0055145 ! ENPP1_HUMAN [Term] id: CCO:P0002517 name: negative regulation of integrin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins." [GOC:go_curators] synonym: "down regulation of integrin biosynthetic process" EXACT [] synonym: "down-regulation of integrin biosynthetic process" EXACT [] synonym: "downregulation of integrin biosynthetic process" EXACT [] synonym: "inhibition of integrin biosynthetic process" NARROW [] synonym: "negative regulation of integrin anabolism" EXACT [] synonym: "negative regulation of integrin biosynthesis" EXACT [] synonym: "negative regulation of integrin formation" EXACT [] synonym: "negative regulation of integrin synthesis" EXACT [] xref: GO:0045720 is_a: CCO:P0002280 ! regulation of integrin biosynthetic process is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis [Term] id: CCO:P0002518 name: negative regulation of gluconeogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of gluconeogenesis" EXACT [] synonym: "down-regulation of gluconeogenesis" EXACT [] synonym: "downregulation of gluconeogenesis" EXACT [] synonym: "inhibition of gluconeogenesis" NARROW [] xref: GO:0045721 is_a: CCO:P0000624 ! regulation of gluconeogenesis is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process relationship: has_participant CCO:B0018508 ! HXK4_HUMAN relationship: has_participant CCO:B0056116 ! ADIPO_HUMAN [Term] id: CCO:P0002519 name: positive regulation of gluconeogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] subset: gosubset_prok synonym: "activation of gluconeogenesis" NARROW [] synonym: "stimulation of gluconeogenesis" NARROW [] synonym: "up regulation of gluconeogenesis" EXACT [] synonym: "up-regulation of gluconeogenesis" EXACT [] synonym: "upregulation of gluconeogenesis" EXACT [] xref: GO:0045722 is_a: CCO:P0000624 ! regulation of gluconeogenesis is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0055542 ! ARP19_HUMAN [Term] id: CCO:P0002520 name: positive regulation of fatty acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids." [GOC:go_curators] subset: gosubset_prok synonym: "activation of fatty acid biosynthetic process" NARROW [] synonym: "positive regulation of fatty acid anabolism" EXACT [] synonym: "positive regulation of fatty acid biosynthesis" EXACT [] synonym: "positive regulation of fatty acid formation" EXACT [] synonym: "positive regulation of fatty acid synthesis" EXACT [] synonym: "stimulation of fatty acid biosynthetic process" NARROW [] synonym: "up regulation of fatty acid biosynthetic process" EXACT [] synonym: "up-regulation of fatty acid biosynthetic process" EXACT [] synonym: "upregulation of fatty acid biosynthetic process" EXACT [] xref: GO:0045723 is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0002055 ! regulation of fatty acid biosynthetic process is_a: CCO:P0002616 ! positive regulation of fatty acid metabolic process relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0056927 ! APOA5_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN [Term] id: CCO:P0002521 name: positive regulation of flagellum biogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation of a flagellum." [GOC:go_curators] synonym: "activation of flagellum biogenesis" NARROW [] synonym: "positive regulation of flagella biogenesis" EXACT [] synonym: "stimulation of flagellum biogenesis" NARROW [] synonym: "up regulation of flagellum biogenesis" EXACT [] synonym: "up-regulation of flagellum biogenesis" EXACT [] synonym: "upregulation of flagellum biogenesis" EXACT [] xref: GO:0045724 is_a: CCO:P0001242 ! regulation of flagellum biogenesis is_a: CCO:P0001423 ! positive regulation of cell projection organization and biogenesis [Term] id: CCO:P0002522 name: positive regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] subset: gosubset_prok synonym: "activation of glycogen biosynthetic process" NARROW [] synonym: "positive regulation of glycogen anabolism" EXACT [] synonym: "positive regulation of glycogen biosynthesis" EXACT [] synonym: "positive regulation of glycogen formation" EXACT [] synonym: "positive regulation of glycogen synthesis" EXACT [] synonym: "stimulation of glycogen biosynthetic process" NARROW [] synonym: "up regulation of glycogen biosynthetic process" EXACT [] synonym: "up-regulation of glycogen biosynthetic process" EXACT [] synonym: "upregulation of glycogen biosynthetic process" EXACT [] xref: GO:0045725 is_a: CCO:P0000621 ! regulation of glycogen biosynthetic process is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process relationship: has_participant CCO:B0005265 ! DYRK2_HUMAN relationship: has_participant CCO:B0018508 ! HXK4_HUMAN relationship: has_participant CCO:B0058555 ! C1QT2_HUMAN [Term] id: CCO:P0002523 name: positive regulation of integrin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins." [GOC:go_curators] synonym: "activation of integrin biosynthetic process" NARROW [] synonym: "positive regulation of integrin anabolism" EXACT [] synonym: "positive regulation of integrin biosynthesis" EXACT [] synonym: "positive regulation of integrin formation" EXACT [] synonym: "positive regulation of integrin synthesis" EXACT [] synonym: "stimulation of integrin biosynthetic process" NARROW [] synonym: "up regulation of integrin biosynthetic process" EXACT [] synonym: "up-regulation of integrin biosynthetic process" EXACT [] synonym: "upregulation of integrin biosynthetic process" EXACT [] xref: GO:0045726 is_a: CCO:P0002280 ! regulation of integrin biosynthetic process is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0059386 ! NOX1_HUMAN [Term] id: CCO:P0002524 name: positive regulation of translation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA." [GOC:dph, GOC:go_curators, GOC:tb] subset: gosubset_prok synonym: "activation of protein biosynthetic process" NARROW [] synonym: "positive regulation of protein anabolism" EXACT [] synonym: "positive regulation of protein biosynthesis" EXACT [] synonym: "positive regulation of protein biosynthetic process" EXACT [GOC:tb] synonym: "positive regulation of protein formation" EXACT [] synonym: "positive regulation of protein synthesis" EXACT [] synonym: "stimulation of protein biosynthetic process" NARROW [] synonym: "up regulation of protein biosynthetic process" EXACT [] synonym: "up-regulation of protein biosynthetic process" EXACT [] synonym: "upregulation of protein biosynthetic process" EXACT [] xref: GO:0045727 xref: GO:0045946 xref: Reactome:110506 is_a: CCO:P0000660 ! regulation of translation is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process relationship: has_participant CCO:B0001508 ! CD28_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0058958 ! BARH2_HUMAN [Term] id: CCO:P0002525 name: regulation of acetate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of acetate breakdown" EXACT [] synonym: "regulation of acetate catabolism" EXACT [] synonym: "regulation of acetate degradation" EXACT [] xref: GO:0045734 is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0002526 name: negative regulation of DNA repair namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA repair." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of DNA repair" EXACT [] synonym: "down-regulation of DNA repair" EXACT [] synonym: "downregulation of DNA repair" EXACT [] synonym: "inhibition of DNA repair" NARROW [] xref: GO:0045738 is_a: CCO:P0000643 ! regulation of DNA repair is_a: CCO:P0003016 ! negative regulation of DNA metabolic process [Term] id: CCO:P0002527 name: positive regulation of DNA repair namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA repair." [GOC:go_curators] subset: gosubset_prok synonym: "activation of DNA repair" NARROW [] synonym: "stimulation of DNA repair" NARROW [] synonym: "up regulation of DNA repair" EXACT [] synonym: "up-regulation of DNA repair" EXACT [] synonym: "upregulation of DNA repair" EXACT [] xref: GO:0045739 is_a: CCO:P0000643 ! regulation of DNA repair is_a: CCO:P0003017 ! positive regulation of DNA metabolic process relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN [Term] id: CCO:P0002528 name: positive regulation of DNA replication namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA replication." [GOC:go_curators] subset: gosubset_prok synonym: "activation of DNA replication" NARROW [] synonym: "stimulation of DNA replication" NARROW [] synonym: "up regulation of DNA replication" EXACT [] synonym: "up-regulation of DNA replication" EXACT [] synonym: "upregulation of DNA replication" EXACT [] xref: GO:0045740 is_a: CCO:P0000639 ! regulation of DNA replication is_a: CCO:P0003017 ! positive regulation of DNA metabolic process relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0020505 ! PGFRA_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0054883 ! PA21B_HUMAN relationship: has_participant CCO:B0054885 ! CSF2_HUMAN relationship: has_participant CCO:B0054922 ! GLI1_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0054965 ! GLI2_HUMAN relationship: has_participant CCO:B0055135 ! SCF_HUMAN relationship: positively_regulates CCO:P0000628 ! DNA replication [Term] id: CCO:P0002529 name: positive regulation of epidermal growth factor receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor activity." [GOC:go_curators] synonym: "activation of epidermal growth factor receptor activity" NARROW [] synonym: "positive regulation of EGF receptor activity" EXACT [] synonym: "positive regulation of EGFR activity" EXACT [] synonym: "stimulation of epidermal growth factor receptor activity" NARROW [] synonym: "up regulation of epidermal growth factor receptor activity" EXACT [] synonym: "up-regulation of epidermal growth factor receptor activity" EXACT [] synonym: "upregulation of epidermal growth factor receptor activity" EXACT [] xref: GO:0045741 is_a: CCO:P0000718 ! regulation of epidermal growth factor receptor activity is_a: CCO:P0002530 ! positive regulation of epidermal growth factor receptor signaling pathway relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0005870 ! TGFA_HUMAN [Term] id: CCO:P0002530 name: positive regulation of epidermal growth factor receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] synonym: "activation of epidermal growth factor receptor signaling pathway" NARROW [] synonym: "positive regulation of EGF receptor signaling pathway" EXACT [] synonym: "positive regulation of EGF receptor signalling pathway" EXACT [] synonym: "positive regulation of EGFR signaling pathway" EXACT [] synonym: "stimulation of epidermal growth factor receptor signaling pathway" NARROW [] synonym: "up regulation of epidermal growth factor receptor signaling pathway" EXACT [] synonym: "up-regulation of epidermal growth factor receptor signaling pathway" EXACT [] synonym: "upregulation of epidermal growth factor receptor signaling pathway" EXACT [] xref: GO:0045742 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002033 ! regulation of epidermal growth factor receptor signaling pathway relationship: has_participant CCO:B0001964 ! AF1L2_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0037429 ! CNRG_HUMAN relationship: has_participant CCO:B0037430 ! CNCG_HUMAN relationship: positively_regulates CCO:P0000715 ! epidermal growth factor receptor signaling pathway [Term] id: CCO:P0002531 name: positive regulation of fibroblast growth factor receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity." [GOC:go_curators] synonym: "activation of fibroblast growth factor receptor signaling pathway" NARROW [] synonym: "positive regulation of FGF receptor signaling pathway" EXACT [] synonym: "positive regulation of FGF receptor signalling pathway" EXACT [] synonym: "positive regulation of FGFR signaling pathway" EXACT [] synonym: "stimulation of fibroblast growth factor receptor signaling pathway" NARROW [] synonym: "up regulation of fibroblast growth factor receptor signaling pathway" EXACT [] synonym: "up-regulation of fibroblast growth factor receptor signaling pathway" EXACT [] synonym: "upregulation of fibroblast growth factor receptor signaling pathway" EXACT [] xref: GO:0045743 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002026 ! regulation of fibroblast growth factor receptor signaling pathway relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: positively_regulates CCO:P0000823 ! fibroblast growth factor receptor signaling pathway [Term] id: CCO:P0002532 name: negative regulation of G-protein coupled receptor protein signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity." [GOC:go_curators] synonym: "down regulation of G-protein coupled receptor protein signaling pathway" EXACT [] synonym: "down-regulation of G-protein coupled receptor protein signaling pathway" EXACT [] synonym: "downregulation of G-protein coupled receptor protein signaling pathway" EXACT [] synonym: "inhibition of G-protein coupled receptor protein signaling pathway" NARROW [] synonym: "negative regulation of G protein coupled receptor protein signaling pathway" EXACT [] synonym: "negative regulation of G protein coupled receptor protein signalling pathway" EXACT [] synonym: "negative regulation of G-protein coupled receptor protein signalling pathway" EXACT [] synonym: "negative regulation of G-protein-coupled receptor protein signaling pathway" EXACT [] synonym: "negative regulation of G-protein-coupled receptor protein signalling pathway" EXACT [] synonym: "negative regulation of GPCR protein signaling pathway" EXACT [] synonym: "negative regulation of GPCR protein signalling pathway" EXACT [] xref: GO:0045744 is_a: CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: has_participant CCO:B0020777 ! RGS13_HUMAN relationship: negatively_regulates CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0002533 name: positive regulation of G-protein coupled receptor protein signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity." [GOC:go_curators] synonym: "activation of G-protein coupled receptor protein signaling pathway" NARROW [] synonym: "positive regulation of G protein coupled receptor protein signaling pathway" EXACT [] synonym: "positive regulation of G protein coupled receptor protein signalling pathway" EXACT [] synonym: "positive regulation of G-protein coupled receptor protein signalling pathway" EXACT [] synonym: "positive regulation of G-protein-coupled receptor protein signaling pathway" EXACT [] synonym: "positive regulation of G-protein-coupled receptor protein signalling pathway" EXACT [] synonym: "positive regulation of GPCR protein signaling pathway" EXACT [] synonym: "positive regulation of GPCR protein signalling pathway" EXACT [] synonym: "stimulation of G-protein coupled receptor protein signaling pathway" NARROW [] synonym: "up regulation of G-protein coupled receptor protein signaling pathway" EXACT [] synonym: "up-regulation of G-protein coupled receptor protein signaling pathway" EXACT [] synonym: "upregulation of G-protein coupled receptor protein signaling pathway" EXACT [] xref: GO:0045745 is_a: CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway is_a: CCO:P0000885 ! positive regulation of signal transduction relationship: has_participant CCO:B0037429 ! CNRG_HUMAN relationship: has_participant CCO:B0037430 ! CNCG_HUMAN relationship: has_participant CCO:B0059012 ! TMOD2_HUMAN relationship: has_participant CCO:B0059393 ! GPR44_HUMAN relationship: positively_regulates CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0002534 name: negative regulation of Notch signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the Notch signaling pathway." [GOC:go_curators] synonym: "down regulation of Notch signaling pathway" EXACT [] synonym: "down-regulation of Notch signaling pathway" EXACT [] synonym: "downregulation of Notch signaling pathway" EXACT [] synonym: "inhibition of Notch signaling pathway" NARROW [] synonym: "negative regulation of N signaling pathway" EXACT [] synonym: "negative regulation of N signalling pathway" EXACT [] synonym: "negative regulation of Notch signalling pathway" EXACT [] xref: GO:0045746 is_a: CCO:P0000829 ! regulation of Notch signaling pathway is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: has_participant CCO:B0005521 ! IKBA_HUMAN relationship: negatively_regulates CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:P0002535 name: positive regulation of Notch signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway." [GOC:go_curators] synonym: "activation of Notch signaling pathway" NARROW [] synonym: "positive regulation of N signaling pathway" EXACT [] synonym: "positive regulation of N signalling pathway" EXACT [] synonym: "positive regulation of Notch signalling pathway" EXACT [] synonym: "stimulation of Notch signaling pathway" NARROW [] synonym: "up regulation of Notch signaling pathway" EXACT [] synonym: "up-regulation of Notch signaling pathway" EXACT [] synonym: "upregulation of Notch signaling pathway" EXACT [] xref: GO:0045747 is_a: CCO:P0000829 ! regulation of Notch signaling pathway is_a: CCO:P0000885 ! positive regulation of signal transduction relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0028290 ! JAG1_HUMAN relationship: positively_regulates CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:P0002536 name: negative regulation of Toll signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the Tl signaling pathway." [GOC:go_curators] synonym: "down regulation of Toll signaling pathway" EXACT [] synonym: "down-regulation of Toll signaling pathway" EXACT [] synonym: "downregulation of Toll signaling pathway" EXACT [] synonym: "inhibition of Toll signaling pathway" NARROW [] synonym: "negative regulation of Tl signaling pathway" EXACT [] synonym: "negative regulation of Tl signalling pathway" EXACT [] xref: GO:0045751 is_a: CCO:P0000828 ! regulation of Toll signaling pathway is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: has_participant CCO:B0055574 ! NAL12_HUMAN relationship: negatively_regulates CCO:P0000810 ! Toll signaling pathway [Term] id: CCO:P0002537 name: positive regulation of Toll signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway." [GOC:go_curators] synonym: "activation of Toll signaling pathway" NARROW [] synonym: "positive regulation of Tl signaling pathway" EXACT [] synonym: "positive regulation of Tl signalling pathway" EXACT [] synonym: "stimulation of Toll signaling pathway" NARROW [] synonym: "up regulation of Toll signaling pathway" EXACT [] synonym: "up-regulation of Toll signaling pathway" EXACT [] synonym: "upregulation of Toll signaling pathway" EXACT [] xref: GO:0045752 is_a: CCO:P0000828 ! regulation of Toll signaling pathway is_a: CCO:P0000885 ! positive regulation of signal transduction relationship: positively_regulates CCO:P0000810 ! Toll signaling pathway [Term] id: CCO:P0002538 name: negative regulation of acetate catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of acetate catabolic process" EXACT [] synonym: "down-regulation of acetate catabolic process" EXACT [] synonym: "downregulation of acetate catabolic process" EXACT [] synonym: "inhibition of acetate catabolic process" NARROW [] synonym: "negative regulation of acetate breakdown" EXACT [] synonym: "negative regulation of acetate catabolism" EXACT [] synonym: "negative regulation of acetate degradation" EXACT [] xref: GO:0045753 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0002525 ! regulation of acetate catabolic process [Term] id: CCO:P0002539 name: positive regulation of acetate catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] subset: gosubset_prok synonym: "activation of acetate catabolic process" NARROW [] synonym: "positive regulation of acetate breakdown" EXACT [] synonym: "positive regulation of acetate catabolism" EXACT [] synonym: "positive regulation of acetate degradation" EXACT [] synonym: "stimulation of acetate catabolic process" NARROW [] synonym: "up regulation of acetate catabolic process" EXACT [] synonym: "up-regulation of acetate catabolic process" EXACT [] synonym: "upregulation of acetate catabolic process" EXACT [] xref: GO:0045754 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0002525 ! regulation of acetate catabolic process [Term] id: CCO:P0002540 name: negative regulation of initiation of acetate catabolic process by acetate namespace: biological_process def: "Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of initiation of acetate catabolic process by acetate" EXACT [] synonym: "down-regulation of initiation of acetate catabolic process by acetate" EXACT [] synonym: "downregulation of initiation of acetate catabolic process by acetate" EXACT [] synonym: "inhibition of initiation of acetate catabolic process by acetate" NARROW [] synonym: "negative regulation of initiation of acetate breakdown by acetate" EXACT [] synonym: "negative regulation of initiation of acetate degradation by acetate" EXACT [] xref: GO:0045755 is_a: CCO:P0002283 ! regulation of initiation of acetate catabolic process by acetate relationship: negatively_regulates CCO:P0002282 ! initiation of acetate catabolic process by acetate [Term] id: CCO:P0002541 name: positive regulation of initiation of acetate catabolic process by acetate namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] subset: gosubset_prok synonym: "activation of initiation of acetate catabolic process by acetate" NARROW [] synonym: "positive regulation of initiation of acetate breakdown by acetate" EXACT [] synonym: "positive regulation of initiation of acetate degradation by acetate" EXACT [] synonym: "stimulation of initiation of acetate catabolic process by acetate" NARROW [] synonym: "up regulation of initiation of acetate catabolic process by acetate" EXACT [] synonym: "up-regulation of initiation of acetate catabolic process by acetate" EXACT [] synonym: "upregulation of initiation of acetate catabolic process by acetate" EXACT [] xref: GO:0045756 is_a: CCO:P0002283 ! regulation of initiation of acetate catabolic process by acetate relationship: positively_regulates CCO:P0002282 ! initiation of acetate catabolic process by acetate [Term] id: CCO:P0002542 name: negative regulation of amino acid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of amino acid metabolic process" EXACT [] synonym: "down-regulation of amino acid metabolic process" EXACT [] synonym: "downregulation of amino acid metabolic process" EXACT [] synonym: "inhibition of amino acid metabolic process" NARROW [] synonym: "negative regulation of amino acid metabolism" EXACT [] xref: GO:0045763 is_a: CCO:P0000668 ! regulation of amino acid metabolic process is_a: CCO:P0001818 ! negative regulation of amine metabolic process [Term] id: CCO:P0002543 name: positive regulation of amino acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] subset: gosubset_prok synonym: "activation of amino acid metabolic process" NARROW [] synonym: "positive regulation of amino acid metabolism" EXACT [] synonym: "stimulation of amino acid metabolic process" NARROW [] synonym: "up regulation of amino acid metabolic process" EXACT [] synonym: "up-regulation of amino acid metabolic process" EXACT [] synonym: "upregulation of amino acid metabolic process" EXACT [] xref: GO:0045764 is_a: CCO:P0000668 ! regulation of amino acid metabolic process is_a: CCO:P0001819 ! positive regulation of amine metabolic process [Term] id: CCO:P0002544 name: regulation of anti-apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of anti-apoptosis." [GOC:go_curators] xref: GO:0045767 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0058510 ! RTKN_HUMAN relationship: regulates CCO:P0000671 ! anti-apoptosis [Term] id: CCO:P0002545 name: positive regulation of anti-apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of anti-apoptosis." [GOC:go_curators] synonym: "activation of anti-apoptosis" NARROW [] synonym: "stimulation of anti-apoptosis" NARROW [] synonym: "up regulation of anti-apoptosis" EXACT [] synonym: "up-regulation of anti-apoptosis" EXACT [] synonym: "upregulation of anti-apoptosis" EXACT [] xref: GO:0045768 is_a: CCO:P0002544 ! regulation of anti-apoptosis relationship: has_participant CCO:B0001508 ! CD28_HUMAN relationship: has_participant CCO:B0005872 ! AAPK1_HUMAN relationship: has_participant CCO:B0005951 ! BRE_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0054545 ! OPA1_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0055904 ! JIP2_HUMAN relationship: has_participant CCO:B0057322 ! RB6I2_HUMAN relationship: positively_regulates CCO:P0000671 ! anti-apoptosis [Term] id: CCO:P0002546 name: negative regulation of asymmetric cell division namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "down regulation of asymmetric cell division" EXACT [] synonym: "down-regulation of asymmetric cell division" EXACT [] synonym: "downregulation of asymmetric cell division" EXACT [] synonym: "inhibition of asymmetric cell division" NARROW [] xref: GO:0045769 is_a: CCO:P0000865 ! regulation of asymmetric cell division is_a: CCO:P0003144 ! negative regulation of cell division relationship: negatively_regulates CCO:P0000821 ! asymmetric cell division [Term] id: CCO:P0002547 name: positive regulation of asymmetric cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "activation of asymmetric cell division" NARROW [] synonym: "stimulation of asymmetric cell division" NARROW [] synonym: "up regulation of asymmetric cell division" EXACT [] synonym: "up-regulation of asymmetric cell division" EXACT [] synonym: "upregulation of asymmetric cell division" EXACT [] xref: GO:0045770 is_a: CCO:P0000865 ! regulation of asymmetric cell division is_a: CCO:P0003143 ! positive regulation of cell division relationship: positively_regulates CCO:P0000821 ! asymmetric cell division [Term] id: CCO:P0002548 name: positive regulation of axon extension namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axon extension." [GOC:go_curators] synonym: "activation of axon extension" NARROW [] synonym: "stimulation of axon extension" NARROW [] synonym: "up regulation of axon extension" EXACT [] synonym: "up-regulation of axon extension" EXACT [] synonym: "upregulation of axon extension" EXACT [] xref: GO:0045773 is_a: CCO:P0001276 ! regulation of axon extension is_a: CCO:P0002950 ! positive regulation of axonogenesis relationship: has_participant CCO:B0005606 ! LIMK1_HUMAN relationship: has_participant CCO:B0054777 ! NET1_HUMAN relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0054976 ! TAU_HUMAN relationship: has_participant CCO:B0055533 ! CADH4_HUMAN relationship: has_participant CCO:B0058838 ! TNR12_HUMAN [Term] id: CCO:P0002549 name: negative regulation of beta 2 integrin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins." [GOC:go_curators] synonym: "down regulation of beta 2 integrin biosynthetic process" EXACT [] synonym: "down-regulation of beta 2 integrin biosynthetic process" EXACT [] synonym: "downregulation of beta 2 integrin biosynthetic process" EXACT [] synonym: "inhibition of beta 2 integrin biosynthetic process" NARROW [] synonym: "negative regulation of beta 2 integrin anabolism" EXACT [] synonym: "negative regulation of beta 2 integrin biosynthesis" EXACT [] synonym: "negative regulation of beta 2 integrin formation" EXACT [] synonym: "negative regulation of beta 2 integrin synthesis" EXACT [] xref: GO:0045774 is_a: CCO:P0002281 ! regulation of beta 2 integrin biosynthetic process is_a: CCO:P0002517 ! negative regulation of integrin biosynthetic process [Term] id: CCO:P0002550 name: positive regulation of beta 2 integrin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins." [GOC:go_curators] synonym: "activation of beta 2 integrin biosynthetic process" NARROW [] synonym: "positive regulation of beta 2 integrin anabolism" EXACT [] synonym: "positive regulation of beta 2 integrin biosynthesis" EXACT [] synonym: "positive regulation of beta 2 integrin formation" EXACT [] synonym: "positive regulation of beta 2 integrin synthesis" EXACT [] synonym: "stimulation of beta 2 integrin biosynthetic process" NARROW [] synonym: "up regulation of beta 2 integrin biosynthetic process" EXACT [] synonym: "up-regulation of beta 2 integrin biosynthetic process" EXACT [] synonym: "upregulation of beta 2 integrin biosynthetic process" EXACT [] xref: GO:0045775 is_a: CCO:P0002281 ! regulation of beta 2 integrin biosynthetic process is_a: CCO:P0002523 ! positive regulation of integrin biosynthetic process [Term] id: CCO:P0002551 name: negative regulation of cell budding namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell budding." [GOC:go_curators] synonym: "down regulation of cell budding" EXACT [] synonym: "down-regulation of cell budding" EXACT [] synonym: "downregulation of cell budding" EXACT [] synonym: "inhibition of cell budding" NARROW [] synonym: "negative regulation of budding" BROAD [] xref: GO:0045781 is_a: CCO:P0000701 ! regulation of cell budding is_a: CCO:P0003144 ! negative regulation of cell division relationship: negatively_regulates CCO:P0000700 ! cell budding [Term] id: CCO:P0002552 name: positive regulation of cell budding namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell budding." [GOC:go_curators] synonym: "activation of cell budding" NARROW [] synonym: "positive regulation of budding" BROAD [] synonym: "stimulation of cell budding" NARROW [] synonym: "up regulation of cell budding" EXACT [] synonym: "up-regulation of cell budding" EXACT [] synonym: "upregulation of cell budding" EXACT [] xref: GO:0045782 is_a: CCO:P0000701 ! regulation of cell budding is_a: CCO:P0003143 ! positive regulation of cell division relationship: positively_regulates CCO:P0000700 ! cell budding [Term] id: CCO:P0002553 name: positive regulation of cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "activation of cell adhesion" NARROW [] synonym: "stimulation of cell adhesion" NARROW [] synonym: "up regulation of cell adhesion" EXACT [] synonym: "up-regulation of cell adhesion" EXACT [] synonym: "upregulation of cell adhesion" EXACT [] xref: GO:0045785 is_a: CCO:P0001245 ! regulation of cell adhesion is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0048975 ! TGM2_HUMAN relationship: has_participant CCO:B0054869 ! SAA_HUMAN relationship: has_participant CCO:B0055037 ! VAV_HUMAN relationship: has_participant CCO:B0055097 ! LOX12_HUMAN relationship: has_participant CCO:B0055114 ! CAP7_HUMAN relationship: has_participant CCO:B0057234 ! Q86SR2_HUMAN [Term] id: CCO:P0002554 name: negative regulation of chromatin assembly or disassembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin assembly or disassembly." [GOC:go_curators] synonym: "down regulation of chromatin assembly or disassembly" EXACT [] synonym: "down-regulation of chromatin assembly or disassembly" EXACT [] synonym: "downregulation of chromatin assembly or disassembly" EXACT [] synonym: "inhibition of chromatin assembly or disassembly" NARROW [] synonym: "negative regulation of chromatin assembly/disassembly" EXACT [] xref: GO:0045798 is_a: CCO:P0000469 ! regulation of chromatin assembly or disassembly is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis is_a: CCO:P0003016 ! negative regulation of DNA metabolic process [Term] id: CCO:P0002555 name: positive regulation of chromatin assembly or disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly." [GOC:go_curators] synonym: "activation of chromatin assembly or disassembly" NARROW [] synonym: "positive regulation of chromatin assembly/disassembly" EXACT [] synonym: "stimulation of chromatin assembly or disassembly" NARROW [] synonym: "up regulation of chromatin assembly or disassembly" EXACT [] synonym: "up-regulation of chromatin assembly or disassembly" EXACT [] synonym: "upregulation of chromatin assembly or disassembly" EXACT [] xref: GO:0045799 is_a: CCO:P0000469 ! regulation of chromatin assembly or disassembly is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis is_a: CCO:P0003017 ! positive regulation of DNA metabolic process [Term] id: CCO:P0002556 name: negative regulation of endocytosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "down regulation of endocytosis" EXACT [] synonym: "down-regulation of endocytosis" EXACT [] synonym: "downregulation of endocytosis" EXACT [] synonym: "inhibition of endocytosis" NARROW [] xref: GO:0045806 is_a: CCO:P0001243 ! regulation of endocytosis is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0059200 ! PACN3_HUMAN [Term] id: CCO:P0002557 name: positive regulation of endocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endocytosis." [GOC:go_curators] synonym: "activation of endocytosis" NARROW [] synonym: "stimulation of endocytosis" NARROW [] synonym: "up regulation of endocytosis" EXACT [] synonym: "up-regulation of endocytosis" EXACT [] synonym: "upregulation of endocytosis" EXACT [] xref: GO:0045807 is_a: CCO:P0001243 ! regulation of endocytosis is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0034087 ! NED4L_HUMAN relationship: has_participant CCO:B0049019 ! IGHM_HUMAN relationship: has_participant CCO:B0054939 ! CD63_HUMAN relationship: has_participant CCO:B0057312 ! MIB1_HUMAN relationship: has_participant CCO:B0058986 ! CALY_HUMAN [Term] id: CCO:P0002558 name: negative regulation of establishment of competence for transformation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of competence for transformation." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of establishment of competence for transformation" EXACT [] synonym: "down-regulation of establishment of competence for transformation" EXACT [] synonym: "downregulation of establishment of competence for transformation" EXACT [] synonym: "inhibition of establishment of competence for transformation" NARROW [] synonym: "inhibitor of the establishment of competence for transformation activity" RELATED [] xref: GO:0045808 is_a: CCO:P0002291 ! regulation of establishment of competence for transformation is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0002559 name: positive regulation of establishment of competence for transformation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation." [GOC:go_curators] synonym: "activation of establishment of competence for transformation" NARROW [] synonym: "activator of the establishment of competence for transformation activity" RELATED [] synonym: "stimulation of establishment of competence for transformation" NARROW [] synonym: "up regulation of establishment of competence for transformation" EXACT [] synonym: "up-regulation of establishment of competence for transformation" EXACT [] synonym: "upregulation of establishment of competence for transformation" EXACT [] xref: GO:0045809 is_a: CCO:P0002291 ! regulation of establishment of competence for transformation is_a: CCO:P0002852 ! positive regulation of cellular process [Term] id: CCO:P0002560 name: negative regulation of Wnt receptor signaling pathway, calcium modulating pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC)." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of frizzled-2 signaling pathway" EXACT [] synonym: "down-regulation of frizzled-2 signaling pathway" EXACT [] synonym: "downregulation of frizzled-2 signaling pathway" EXACT [] synonym: "inhibition of frizzled-2 signaling pathway" NARROW [] synonym: "negative regulation of frizzled-2 signaling pathway" EXACT [] synonym: "negative regulation of frizzled-2 signalling pathway" EXACT [] xref: GO:0045812 is_a: CCO:P0000827 ! regulation of Wnt receptor signaling pathway, calcium modulating pathway is_a: CCO:P0001249 ! negative regulation of Wnt receptor signaling pathway relationship: negatively_regulates CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway [Term] id: CCO:P0002561 name: positive regulation of Wnt receptor signaling pathway, calcium modulating pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the frizzled-2 signaling pathway." [GOC:go_curators] synonym: "activation of frizzled-2 signaling pathway" NARROW [] synonym: "positive regulation of frizzled-2 signaling pathway" EXACT [] synonym: "positive regulation of frizzled-2 signalling pathway" EXACT [] synonym: "stimulation of frizzled-2 signaling pathway" NARROW [] synonym: "up regulation of frizzled-2 signaling pathway" EXACT [] synonym: "up-regulation of frizzled-2 signaling pathway" EXACT [] synonym: "upregulation of frizzled-2 signaling pathway" EXACT [] xref: GO:0045813 is_a: CCO:P0000827 ! regulation of Wnt receptor signaling pathway, calcium modulating pathway is_a: CCO:P0001248 ! positive regulation of Wnt receptor signaling pathway relationship: positively_regulates CCO:P0000757 ! Wnt receptor signaling pathway, calcium modulating pathway [Term] id: CCO:P0002562 name: negative regulation of gene expression, epigenetic namespace: biological_process def: "Any epigenetic process that stops, prevents or reduces the rate of gene expression." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of gene expression, epigenetic" EXACT [] synonym: "down-regulation of gene expression, epigenetic" EXACT [] synonym: "downregulation of gene expression, epigenetic" EXACT [] synonym: "inhibition of gene expression, epigenetic" NARROW [] xref: GO:0045814 is_a: CCO:P0001019 ! negative regulation of gene expression is_a: CCO:P0002023 ! regulation of gene expression, epigenetic relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005981 ! TRI27_HUMAN [Term] id: CCO:P0002563 name: positive regulation of gene expression, epigenetic namespace: biological_process def: "Any epigenetic process that activates or increases the rate of gene expression." [GOC:go_curators] synonym: "activation of gene expression, epigenetic" NARROW [] synonym: "stimulation of gene expression, epigenetic" NARROW [] synonym: "up regulation of gene expression, epigenetic" EXACT [] synonym: "up-regulation of gene expression, epigenetic" EXACT [] synonym: "upregulation of gene expression, epigenetic" EXACT [] xref: GO:0045815 is_a: CCO:P0001018 ! positive regulation of gene expression is_a: CCO:P0002023 ! regulation of gene expression, epigenetic [Term] id: CCO:P0002564 name: negative regulation of transcription from RNA polymerase II promoter, global namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of global transcription from an RNA polymerase II promoter." [GOC:go_curators] synonym: "down regulation of global transcription from RNA polymerase II promoter" EXACT [] synonym: "down-regulation of global transcription from RNA polymerase II promoter" EXACT [] synonym: "downregulation of global transcription from RNA polymerase II promoter" EXACT [] synonym: "inhibition of global transcription from RNA polymerase II promoter" NARROW [] synonym: "negative regulation of global transcription from Pol II promoter" EXACT [] xref: GO:0045816 is_a: CCO:P0000400 ! negative regulation of transcription from RNA polymerase II promoter is_a: CCO:P0000658 ! regulation of transcription from RNA polymerase II promoter, global [Term] id: CCO:P0002565 name: positive regulation of transcription from RNA polymerase II promoter, global namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of global transcription from an RNA polymerase II promoter." [GOC:go_curators] synonym: "activation of global transcription from RNA polymerase II promoter" NARROW [] synonym: "positive regulation of global transcription from Pol II promoter" EXACT [] synonym: "stimulation of global transcription from RNA polymerase II promoter" NARROW [] synonym: "up regulation of global transcription from RNA polymerase II promoter" EXACT [] synonym: "up-regulation of global transcription from RNA polymerase II promoter" EXACT [] synonym: "upregulation of global transcription from RNA polymerase II promoter" EXACT [] xref: GO:0045817 is_a: CCO:P0000658 ! regulation of transcription from RNA polymerase II promoter, global is_a: CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter relationship: has_participant CCO:B0005485 ! SP1_HUMAN relationship: has_participant CCO:B0005680 ! AP2B_HUMAN relationship: has_participant CCO:B0058778 ! ELL3_HUMAN [Term] id: CCO:P0002566 name: negative regulation of glycogen catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of glycogen catabolic process" EXACT [] synonym: "down-regulation of glycogen catabolic process" EXACT [] synonym: "downregulation of glycogen catabolic process" EXACT [] synonym: "inhibition of glycogen catabolic process" NARROW [] synonym: "negative regulation of glycogen breakdown" EXACT [] synonym: "negative regulation of glycogen catabolism" EXACT [] synonym: "negative regulation of glycogen degradation" EXACT [] xref: GO:0045818 is_a: CCO:P0000622 ! regulation of glycogen catabolic process is_a: CCO:P0001411 ! negative regulation of cellular catabolic process relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN [Term] id: CCO:P0002567 name: positive regulation of glycogen catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] subset: gosubset_prok synonym: "activation of glycogen catabolic process" NARROW [] synonym: "positive regulation of glycogen breakdown" EXACT [] synonym: "positive regulation of glycogen catabolism" EXACT [] synonym: "positive regulation of glycogen degradation" EXACT [] synonym: "stimulation of glycogen catabolic process" NARROW [] synonym: "up regulation of glycogen catabolic process" EXACT [] synonym: "up-regulation of glycogen catabolic process" EXACT [] synonym: "upregulation of glycogen catabolic process" EXACT [] xref: GO:0045819 is_a: CCO:P0000622 ! regulation of glycogen catabolic process is_a: CCO:P0001412 ! positive regulation of cellular catabolic process relationship: has_participant CCO:B0038263 ! ADA1B_HUMAN [Term] id: CCO:P0002568 name: negative regulation of glycolysis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycolysis." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of glycolysis" EXACT [] synonym: "down-regulation of glycolysis" EXACT [] synonym: "downregulation of glycolysis" EXACT [] synonym: "inhibition of glycolysis" NARROW [] xref: GO:0045820 is_a: CCO:P0000623 ! regulation of glycolysis is_a: CCO:P0001411 ! negative regulation of cellular catabolic process [Term] id: CCO:P0002569 name: positive regulation of glycolysis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glycolysis." [GOC:go_curators] subset: gosubset_prok synonym: "activation of glycolysis" NARROW [] synonym: "stimulation of glycolysis" NARROW [] synonym: "up regulation of glycolysis" EXACT [] synonym: "up-regulation of glycolysis" EXACT [] synonym: "upregulation of glycolysis" EXACT [] xref: GO:0045821 is_a: CCO:P0000623 ! regulation of glycolysis is_a: CCO:P0001412 ! positive regulation of cellular catabolic process relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005478 ! INSR_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0054351 ! G3PT_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN [Term] id: CCO:P0002570 name: negative regulation of isoprenoid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of isoprenoid metabolic process" EXACT [] synonym: "down-regulation of isoprenoid metabolic process" EXACT [] synonym: "downregulation of isoprenoid metabolic process" EXACT [] synonym: "inhibition of isoprenoid metabolic process" NARROW [] synonym: "negative regulation of isoprenoid metabolism" EXACT [] xref: GO:0045827 is_a: CCO:P0001146 ! regulation of isoprenoid metabolic process is_a: CCO:P0001405 ! negative regulation of cellular metabolic process [Term] id: CCO:P0002571 name: positive regulation of isoprenoid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid." [GOC:go_curators] subset: gosubset_prok synonym: "activation of isoprenoid metabolic process" NARROW [] synonym: "positive regulation of isoprenoid metabolism" EXACT [] synonym: "stimulation of isoprenoid metabolic process" NARROW [] synonym: "up regulation of isoprenoid metabolic process" EXACT [] synonym: "up-regulation of isoprenoid metabolic process" EXACT [] synonym: "upregulation of isoprenoid metabolic process" EXACT [] xref: GO:0045828 is_a: CCO:P0001146 ! regulation of isoprenoid metabolic process is_a: CCO:P0001406 ! positive regulation of cellular metabolic process [Term] id: CCO:P0002572 name: negative regulation of isotype switching namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of isotype switching." [GOC:go_curators] synonym: "down regulation of isotype switching" EXACT [] synonym: "down-regulation of isotype switching" EXACT [] synonym: "downregulation of isotype switching" EXACT [] synonym: "inhibition of isotype switching" NARROW [] synonym: "negative regulation of class switch recombination" EXACT [] synonym: "negative regulation of class switching" EXACT [] synonym: "negative regulation of isotype switch recombination" EXACT [] xref: GO:0045829 is_a: CCO:P0002284 ! regulation of isotype switching is_a: CCO:P0002607 ! negative regulation of DNA recombination is_a: CCO:P0002987 ! negative regulation of B cell activation [Term] id: CCO:P0002573 name: positive regulation of isotype switching namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of isotype switching." [GOC:go_curators] synonym: "activation of isotype switching" NARROW [] synonym: "positive regulation of class switch recombination" EXACT [] synonym: "positive regulation of class switching" EXACT [] synonym: "positive regulation of isotype switch recombination" EXACT [] synonym: "stimulation of isotype switching" NARROW [] synonym: "up regulation of isotype switching" EXACT [] synonym: "up-regulation of isotype switching" EXACT [] synonym: "upregulation of isotype switching" EXACT [] xref: GO:0045830 is_a: CCO:P0002284 ! regulation of isotype switching is_a: CCO:P0002608 ! positive regulation of DNA recombination is_a: CCO:P0002989 ! positive regulation of B cell activation [Term] id: CCO:P0002574 name: negative regulation of nurse cell apoptosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of nurse cell apoptosis." [GOC:go_curators] synonym: "down regulation of nurse cell apoptosis" EXACT [] synonym: "down-regulation of nurse cell apoptosis" EXACT [] synonym: "downregulation of nurse cell apoptosis" EXACT [] synonym: "inhibition of nurse cell apoptosis" NARROW [] xref: GO:0045849 is_a: CCO:P0002148 ! negative regulation of apoptosis is_a: CCO:P0002370 ! regulation of nurse cell apoptosis [Term] id: CCO:P0002575 name: positive regulation of nurse cell apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nurse cell apoptosis." [GOC:go_curators] synonym: "activation of nurse cell apoptosis" NARROW [] synonym: "stimulation of nurse cell apoptosis" NARROW [] synonym: "up regulation of nurse cell apoptosis" EXACT [] synonym: "up-regulation of nurse cell apoptosis" EXACT [] synonym: "upregulation of nurse cell apoptosis" EXACT [] xref: GO:0045850 is_a: CCO:P0002147 ! positive regulation of apoptosis is_a: CCO:P0002370 ! regulation of nurse cell apoptosis [Term] id: CCO:P0002576 name: negative regulation of molecular function, epigenetic namespace: biological_process def: "Any heritable epigenetic process that stops, prevents or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of protein activity, epigenetic" EXACT [] synonym: "down-regulation of protein activity, epigenetic" EXACT [] synonym: "downregulation of protein activity, epigenetic" EXACT [] synonym: "inhibition of protein activity, epigenetic" NARROW [] synonym: "negative regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb] xref: GO:0045857 is_a: CCO:P0002024 ! regulation of molecular function, epigenetic is_a: CCO:P0002562 ! negative regulation of gene expression, epigenetic [Term] id: CCO:P0002577 name: positive regulation of molecular function, epigenetic namespace: biological_process def: "Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of protein activity, epigenetic" NARROW [] synonym: "positive regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of protein activity, epigenetic" NARROW [] synonym: "up regulation of protein activity, epigenetic" EXACT [] synonym: "up-regulation of protein activity, epigenetic" EXACT [] synonym: "upregulation of protein activity, epigenetic" EXACT [] xref: GO:0045858 is_a: CCO:P0002024 ! regulation of molecular function, epigenetic is_a: CCO:P0002563 ! positive regulation of gene expression, epigenetic [Term] id: CCO:P0002578 name: negative regulation of proteolysis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of proteolysis" EXACT [] synonym: "down-regulation of proteolysis" EXACT [] synonym: "downregulation of proteolysis" EXACT [] synonym: "inhibition of proteolysis" NARROW [] synonym: "negative regulation of peptidolysis" EXACT [] xref: GO:0045861 is_a: CCO:P0001246 ! regulation of proteolysis is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process relationship: has_participant CCO:B0014899 ! IPSP_HUMAN relationship: has_participant CCO:B0054852 ! INS_HUMAN relationship: has_participant CCO:B0058258 ! DNJC1_HUMAN relationship: has_participant CCO:B0059091 ! CLN8_HUMAN relationship: has_participant CCO:B0059221 ! RAB23_HUMAN [Term] id: CCO:P0002579 name: positive regulation of proteolysis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." [GOC:go_curators] subset: gosubset_prok synonym: "activation of proteolysis" NARROW [] synonym: "positive regulation of peptidolysis" EXACT [] synonym: "stimulation of proteolysis" NARROW [] synonym: "up regulation of proteolysis" EXACT [] synonym: "up-regulation of proteolysis" EXACT [] synonym: "upregulation of proteolysis" EXACT [] xref: GO:0045862 is_a: CCO:P0001246 ! regulation of proteolysis is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process relationship: has_participant CCO:B0002171 ! AKIP_HUMAN relationship: has_participant CCO:B0055873 ! IFT88_HUMAN relationship: has_participant CCO:B0058942 ! CLN6_HUMAN relationship: has_participant CCO:B0059332 ! IFT52_HUMAN [Term] id: CCO:P0002580 name: negative regulation of pteridine metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of pteridine metabolic process" EXACT [] synonym: "down-regulation of pteridine metabolic process" EXACT [] synonym: "downregulation of pteridine metabolic process" EXACT [] synonym: "inhibition of pteridine metabolic process" NARROW [] synonym: "negative regulation of pteridine metabolism" EXACT [] xref: GO:0045863 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0002036 ! regulation of pteridine metabolic process [Term] id: CCO:P0002581 name: positive regulation of pteridine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine." [GOC:go_curators] subset: gosubset_prok synonym: "activation of pteridine metabolic process" NARROW [] synonym: "positive regulation of pteridine metabolism" EXACT [] synonym: "stimulation of pteridine metabolic process" NARROW [] synonym: "up regulation of pteridine metabolic process" EXACT [] synonym: "up-regulation of pteridine metabolic process" EXACT [] synonym: "upregulation of pteridine metabolic process" EXACT [] xref: GO:0045864 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0002036 ! regulation of pteridine metabolic process [Term] id: CCO:P0002582 name: negative regulation of rhodopsin gene expression namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of rhodopsin gene expression." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of rhodopsin gene activity" EXACT [] synonym: "down-regulation of rhodopsin gene activity" EXACT [] synonym: "downregulation of rhodopsin gene activity" EXACT [] synonym: "inhibition of rhodopsin gene activity" NARROW [] synonym: "negative regulation of rhodopsin gene activity" EXACT [GOC:dph, GOC:tb] xref: GO:0045871 is_a: CCO:P0000795 ! regulation of rhodopsin gene expression is_a: CCO:P0001019 ! negative regulation of gene expression [Term] id: CCO:P0002583 name: positive regulation of rhodopsin gene expression namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of rhodopsin gene expression." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of rhodopsin gene activity" NARROW [] synonym: "positive regulation of rhodopsin gene activity" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of rhodopsin gene activity" NARROW [] synonym: "up regulation of rhodopsin gene activity" EXACT [] synonym: "up-regulation of rhodopsin gene activity" EXACT [] synonym: "upregulation of rhodopsin gene activity" EXACT [] xref: GO:0045872 is_a: CCO:P0000795 ! regulation of rhodopsin gene expression is_a: CCO:P0001018 ! positive regulation of gene expression [Term] id: CCO:P0002584 name: negative regulation of sevenless signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the sevenless signaling pathway." [GOC:go_curators] synonym: "down regulation of sevenless signaling pathway" EXACT [] synonym: "down-regulation of sevenless signaling pathway" EXACT [] synonym: "downregulation of sevenless signaling pathway" EXACT [] synonym: "inhibition of sevenless signaling pathway" NARROW [] synonym: "negative regulation of sev signaling pathway" EXACT [] synonym: "negative regulation of sevenless signalling pathway" EXACT [] xref: GO:0045873 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002372 ! regulation of sevenless signaling pathway relationship: negatively_regulates CCO:P0002371 ! sevenless signaling pathway [Term] id: CCO:P0002585 name: positive regulation of sevenless signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway." [GOC:go_curators] synonym: "activation of sevenless signaling pathway" NARROW [] synonym: "positive regulation of sev signaling pathway" EXACT [] synonym: "positive regulation of sevenless signalling pathway" EXACT [] synonym: "stimulation of sevenless signaling pathway" NARROW [] synonym: "up regulation of sevenless signaling pathway" EXACT [] synonym: "up-regulation of sevenless signaling pathway" EXACT [] synonym: "upregulation of sevenless signaling pathway" EXACT [] xref: GO:0045874 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002372 ! regulation of sevenless signaling pathway relationship: positively_regulates CCO:P0002371 ! sevenless signaling pathway [Term] id: CCO:P0002586 name: negative regulation of smoothened signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling." [GOC:go_curators] synonym: "down regulation of smoothened signaling pathway" EXACT [] synonym: "down-regulation of smoothened signaling pathway" EXACT [] synonym: "downregulation of smoothened signaling pathway" EXACT [] synonym: "inhibition of smoothened signaling pathway" NARROW [] synonym: "negative regulation of smoothened activity" RELATED [] synonym: "negative regulation of smoothened by patched" NARROW [] synonym: "negative regulation of smoothened receptor activity by patched" RELATED [] synonym: "negative regulation of smoothened signalling pathway" EXACT [] xref: GO:0045877 xref: GO:0045879 is_a: CCO:P0000826 ! regulation of smoothened signaling pathway is_a: CCO:P0000886 ! negative regulation of signal transduction relationship: has_participant CCO:B0015164 ! HHIP_HUMAN relationship: negatively_regulates CCO:P0000758 ! smoothened signaling pathway [Term] id: CCO:P0002587 name: positive regulation of smoothened signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smoothened signaling." [GOC:go_curators] synonym: "activation of smoothened signaling pathway" NARROW [] synonym: "positive regulation of smoothened by patched" RELATED [] synonym: "positive regulation of smoothened receptor activity by patched" RELATED [] synonym: "positive regulation of smoothened signalling pathway" EXACT [] synonym: "stimulation of smoothened signaling pathway" NARROW [] synonym: "up regulation of smoothened signaling pathway" EXACT [] synonym: "up-regulation of smoothened signaling pathway" EXACT [] synonym: "upregulation of smoothened signaling pathway" EXACT [] xref: GO:0045878 xref: GO:0045880 is_a: CCO:P0000826 ! regulation of smoothened signaling pathway is_a: CCO:P0000885 ! positive regulation of signal transduction relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0005824 ! CTNA1_HUMAN relationship: positively_regulates CCO:P0000758 ! smoothened signaling pathway [Term] id: CCO:P0002588 name: positive regulation of sporulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sporulation." [GOC:go_curators] synonym: "activation of sporulation" NARROW [] synonym: "stimulation of sporulation" NARROW [] synonym: "up regulation of sporulation" EXACT [] synonym: "up-regulation of sporulation" EXACT [] synonym: "upregulation of sporulation" EXACT [] xref: GO:0045881 is_a: CCO:P0002048 ! regulation of sporulation is_a: CCO:P0002411 ! positive regulation of cell differentiation [Term] id: CCO:P0002589 name: negative regulation of sulfur utilization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sulfur utilization." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of sulfur utilization" EXACT [] synonym: "down-regulation of sulfur utilization" EXACT [] synonym: "downregulation of sulfur utilization" EXACT [] synonym: "inhibition of sulfur utilization" NARROW [] synonym: "negative regulation of sulphur utilization" EXACT [] xref: GO:0045882 is_a: CCO:P0000669 ! regulation of sulfur utilization is_a: CCO:P0003054 ! negative regulation of sulfur metabolic process [Term] id: CCO:P0002590 name: positive regulation of sulfur utilization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sulfur utilization." [GOC:go_curators] subset: gosubset_prok synonym: "activation of sulfur utilization" NARROW [] synonym: "positive regulation of sulphur utilization" EXACT [] synonym: "stimulation of sulfur utilization" NARROW [] synonym: "up regulation of sulfur utilization" EXACT [] synonym: "up-regulation of sulfur utilization" EXACT [] synonym: "upregulation of sulfur utilization" EXACT [] xref: GO:0045883 is_a: CCO:P0000669 ! regulation of sulfur utilization is_a: CCO:P0003055 ! positive regulation of sulfur metabolic process [Term] id: CCO:P0002591 name: regulation of survival gene product expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of survival gene product activity" EXACT [GOC:dph, GOC:tb] synonym: "regulation of survival gene products" EXACT [] xref: GO:0045884 is_a: CCO:P0000671 ! anti-apoptosis is_a: CCO:P0000947 ! regulation of gene expression relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0058160 ! AKTS1_HUMAN [Term] id: CCO:P0002592 name: positive regulation of survival gene product expression namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of survival gene product activity" NARROW [] synonym: "positive regulation of survival gene product activity" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of survival gene products" EXACT [] synonym: "stimulation of survival gene product activity" NARROW [] synonym: "up regulation of survival gene product activity" EXACT [] synonym: "up-regulation of survival gene product activity" EXACT [] synonym: "upregulation of survival gene product activity" EXACT [] xref: GO:0045885 is_a: CCO:P0001018 ! positive regulation of gene expression is_a: CCO:P0002591 ! regulation of survival gene product expression relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0005652 ! ESR1_HUMAN relationship: has_participant CCO:B0042813 ! IL2RB_HUMAN relationship: has_participant CCO:B0054885 ! CSF2_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0059296 ! TN13B_HUMAN [Term] id: CCO:P0002593 name: negative regulation of synaptic growth at neuromuscular junction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction." [GOC:go_curators] synonym: "down regulation of synaptic growth at neuromuscular junction" EXACT [] synonym: "down-regulation of synaptic growth at neuromuscular junction" EXACT [] synonym: "downregulation of synaptic growth at neuromuscular junction" EXACT [] synonym: "inhibition of synaptic growth at neuromuscular junction" NARROW [] xref: GO:0045886 is_a: CCO:P0000824 ! regulation of synaptic growth at neuromuscular junction is_a: CCO:P0003167 ! negative regulation of synaptogenesis [Term] id: CCO:P0002594 name: positive regulation of synaptic growth at neuromuscular junction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction." [GOC:go_curators] synonym: "activation of synaptic growth at neuromuscular junction" NARROW [] synonym: "stimulation of synaptic growth at neuromuscular junction" NARROW [] synonym: "up regulation of synaptic growth at neuromuscular junction" EXACT [] synonym: "up-regulation of synaptic growth at neuromuscular junction" EXACT [] synonym: "upregulation of synaptic growth at neuromuscular junction" EXACT [] xref: GO:0045887 is_a: CCO:P0000824 ! regulation of synaptic growth at neuromuscular junction is_a: CCO:P0003168 ! positive regulation of synaptogenesis [Term] id: CCO:P0002595 name: negative regulation of transcription, DNA-dependent namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of transcription, DNA-dependent" EXACT [] synonym: "down-regulation of transcription, DNA-dependent" EXACT [] synonym: "downregulation of transcription, DNA-dependent" EXACT [] synonym: "inhibition of transcription, DNA-dependent" NARROW [] xref: GO:0045892 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent is_a: CCO:P0001129 ! negative regulation of transcription is_a: CCO:P0003069 ! negative regulation of RNA metabolic process relationship: has_participant CCO:B0001347 ! FOXN3_HUMAN relationship: has_participant CCO:B0001365 ! TBX3_HUMAN relationship: has_participant CCO:B0001559 ! 1433T_HUMAN relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0002146 ! TF7L1_HUMAN relationship: has_participant CCO:B0002148 ! CHM1A_HUMAN relationship: has_participant CCO:B0002196 ! DAXX_HUMAN relationship: has_participant CCO:B0002234 ! ING4_HUMAN relationship: has_participant CCO:B0002239 ! PA2G4_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005357 ! SIN3A_HUMAN relationship: has_participant CCO:B0005395 ! ZHX1_HUMAN relationship: has_participant CCO:B0005416 ! SMCE1_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005696 ! DNJB6_HUMAN relationship: has_participant CCO:B0005779 ! ENOA_HUMAN relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN relationship: has_participant CCO:B0005907 ! P66A_HUMAN relationship: has_participant CCO:B0015239 ! FOXK1_HUMAN relationship: has_participant CCO:B0016719 ! FOXF2_HUMAN relationship: has_participant CCO:B0017945 ! PURB_HUMAN relationship: has_participant CCO:B0022038 ! ZHX2_HUMAN relationship: has_participant CCO:B0022040 ! ZHX3_HUMAN relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0023371 ! HIC2_HUMAN relationship: has_participant CCO:B0032607 ! DNMT1_HUMAN relationship: has_participant CCO:B0037049 ! TRI66_HUMAN relationship: has_participant CCO:B0039070 ! PHF12_HUMAN relationship: has_participant CCO:B0040516 ! RS14_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN relationship: has_participant CCO:B0054387 ! KLF11_HUMAN relationship: has_participant CCO:B0054483 ! KLF4_HUMAN relationship: has_participant CCO:B0054751 ! ZBT7A_HUMAN relationship: has_participant CCO:B0054943 ! STP1_HUMAN relationship: has_participant CCO:B0055403 ! SOX9_HUMAN relationship: has_participant CCO:B0055483 ! NR0B1_HUMAN relationship: has_participant CCO:B0055679 ! PURA_HUMAN relationship: has_participant CCO:B0055743 ! ZBT16_HUMAN relationship: has_participant CCO:B0055767 ! SUH_HUMAN relationship: has_participant CCO:B0055809 ! RIPP1_HUMAN relationship: has_participant CCO:B0055886 ! TBX2_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056962 ! MCAF1_HUMAN relationship: has_participant CCO:B0056966 ! BCOR_HUMAN relationship: has_participant CCO:B0057244 ! LDB1_HUMAN relationship: has_participant CCO:B0057286 ! CIR_HUMAN relationship: has_participant CCO:B0057496 ! Q8N717_HUMAN relationship: has_participant CCO:B0057994 ! TWST2_HUMAN relationship: has_participant CCO:B0058302 ! ZN396_HUMAN relationship: has_participant CCO:B0058398 ! RSF1_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN relationship: has_participant CCO:B0059028 ! NDUAD_HUMAN relationship: has_participant CCO:B0059130 ! MLX_HUMAN relationship: has_participant CCO:B0059138 ! TRPS1_HUMAN relationship: has_participant CCO:B0059305 ! SBNO2_HUMAN relationship: has_participant CCO:B0059339 ! CBY1_HUMAN [Term] id: CCO:P0002596 name: positive regulation of transcription, DNA-dependent namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription." [GOC:go_curators] subset: gosubset_prok synonym: "activation of transcription, DNA-dependent" NARROW [] synonym: "stimulation of transcription, DNA-dependent" NARROW [] synonym: "up regulation of transcription, DNA-dependent" EXACT [] synonym: "up-regulation of transcription, DNA-dependent" EXACT [] synonym: "upregulation of transcription, DNA-dependent" EXACT [] xref: GO:0045893 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent is_a: CCO:P0002625 ! positive regulation of transcription is_a: CCO:P0003070 ! positive regulation of RNA metabolic process relationship: has_participant CCO:B0001374 ! P73_HUMAN relationship: has_participant CCO:B0001451 ! YETS4_HUMAN relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0001598 ! BRCA1_HUMAN relationship: has_participant CCO:B0001630 ! CTCF_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001693 ! RAN_HUMAN relationship: has_participant CCO:B0001734 ! ILF3_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0001776 ! TFDP1_HUMAN relationship: has_participant CCO:B0001964 ! AF1L2_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0005260 ! NIF3L_HUMAN relationship: has_participant CCO:B0005321 ! PIAS2_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005351 ! TIP60_HUMAN relationship: has_participant CCO:B0005410 ! KU70_HUMAN relationship: has_participant CCO:B0005412 ! TP53B_HUMAN relationship: has_participant CCO:B0005417 ! SMRC2_HUMAN relationship: has_participant CCO:B0005418 ! SMRC1_HUMAN relationship: has_participant CCO:B0005485 ! SP1_HUMAN relationship: has_participant CCO:B0005579 ! PIAS1_HUMAN relationship: has_participant CCO:B0005715 ! ITF2_HUMAN relationship: has_participant CCO:B0005830 ! FHL2_HUMAN relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0006057 ! TFE2_HUMAN relationship: has_participant CCO:B0015239 ! FOXK1_HUMAN relationship: has_participant CCO:B0016694 ! FOXI1_HUMAN relationship: has_participant CCO:B0016695 ! FOXE1_HUMAN relationship: has_participant CCO:B0016699 ! FOXF1_HUMAN relationship: has_participant CCO:B0016719 ! FOXF2_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0017844 ! TGFI1_HUMAN relationship: has_participant CCO:B0017947 ! PHF5A_HUMAN relationship: has_participant CCO:B0018382 ! CREB5_HUMAN relationship: has_participant CCO:B0020948 ! MP2K3_HUMAN relationship: has_participant CCO:B0022300 ! P63_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0038846 ! ERR3_HUMAN relationship: has_participant CCO:B0041593 ! NCOA4_HUMAN relationship: has_participant CCO:B0043428 ! NCOA3_HUMAN relationship: has_participant CCO:B0048954 ! IL31R_HUMAN relationship: has_participant CCO:B0049848 ! RNF4_HUMAN relationship: has_participant CCO:B0054404 ! ARHGB_HUMAN relationship: has_participant CCO:B0054690 ! S14L2_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0055003 ! ODBA_HUMAN relationship: has_participant CCO:B0055166 ! GATA3_HUMAN relationship: has_participant CCO:B0055299 ! HNF1B_HUMAN relationship: has_participant CCO:B0055369 ! GATA4_HUMAN relationship: has_participant CCO:B0055370 ! NKX21_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN relationship: has_participant CCO:B0055501 ! RM12_HUMAN relationship: has_participant CCO:B0055506 ! NKX25_HUMAN relationship: has_participant CCO:B0055771 ! PAX8_HUMAN relationship: has_participant CCO:B0055855 ! ILF2_HUMAN relationship: has_participant CCO:B0055961 ! SRTD2_HUMAN relationship: has_participant CCO:B0056112 ! NCOA1_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056848 ! NARGL_HUMAN relationship: has_participant CCO:B0056941 ! SMRD3_HUMAN relationship: has_participant CCO:B0056962 ! MCAF1_HUMAN relationship: has_participant CCO:B0057209 ! TAF8_HUMAN relationship: has_participant CCO:B0058266 ! NSD1_HUMAN relationship: has_participant CCO:B0058340 ! TREF1_HUMAN relationship: has_participant CCO:B0058403 ! MMS19_HUMAN relationship: has_participant CCO:B0058414 ! NOTC4_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: has_participant CCO:B0058556 ! NARG1_HUMAN relationship: has_participant CCO:B0058656 ! PHS2_HUMAN relationship: has_participant CCO:B0058705 ! TXND1_HUMAN relationship: has_participant CCO:B0058835 ! WBS14_HUMAN relationship: has_participant CCO:B0058991 ! EHF_HUMAN relationship: has_participant CCO:B0059043 ! MDFIC_HUMAN relationship: has_participant CCO:B0059083 ! RNF14_HUMAN relationship: has_participant CCO:B0059162 ! KLF15_HUMAN relationship: has_participant CCO:B0059343 ! GRIP1_HUMAN relationship: has_participant CCO:B0059349 ! DYR1B_HUMAN [Term] id: CCO:P0002597 name: negative regulation of transcription, mating-type specific namespace: biological_process def: "Any mating-type specific process that stops, prevents or reduces the rate of transcription." [GOC:go_curators] synonym: "down regulation of transcription, mating-type specific" EXACT [] synonym: "down-regulation of transcription, mating-type specific" EXACT [] synonym: "downregulation of transcription, mating-type specific" EXACT [] synonym: "inhibition of transcription, mating-type specific" NARROW [] xref: GO:0045894 is_a: CCO:P0000797 ! regulation of transcription, mating-type specific is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:P0002598 name: positive regulation of transcription, mating-type specific namespace: biological_process def: "Any mating-type specific process that activates or increases the rate of transcription." [GOC:go_curators] synonym: "activation of transcription, mating-type specific" NARROW [] synonym: "stimulation of transcription, mating-type specific" NARROW [] synonym: "up regulation of transcription, mating-type specific" EXACT [] synonym: "up-regulation of transcription, mating-type specific" EXACT [] synonym: "upregulation of transcription, mating-type specific" EXACT [] xref: GO:0045895 is_a: CCO:P0000797 ! regulation of transcription, mating-type specific is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:P0002599 name: regulation of transcriptional preinitiation complex assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcriptional preinitiation complex assebly." [GOC:go_curators] synonym: "regulation of transcriptional pre-initiation complex assembly" EXACT [] synonym: "regulation of transcriptional pre-initiation complex biosynthesis" EXACT [] synonym: "regulation of transcriptional preinitiation complex formation" RELATED [] xref: GO:0045898 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0056962 ! MCAF1_HUMAN relationship: regulates CCO:P0003028 ! transcriptional preinitiation complex assembly [Term] id: CCO:P0002600 name: positive regulation of transcriptional preinitiation complex assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcriptional preinitiation complex assembly." [GOC:go_curators] synonym: "activation of transcriptional preinitiation complex assembly" NARROW [] synonym: "positive regulation of transcriptional pre-initiation complex assembly" EXACT [] synonym: "positive regulation of transcriptional pre-initiation complex biosynthesis" EXACT [] synonym: "positive regulation of transcriptional preinitiation complex formation" EXACT [] synonym: "stimulation of transcriptional preinitiation complex assembly" NARROW [] synonym: "up regulation of transcriptional preinitiation complex assembly" EXACT [] synonym: "up-regulation of transcriptional preinitiation complex assembly" EXACT [] synonym: "upregulation of transcriptional preinitiation complex assembly" EXACT [] xref: GO:0045899 is_a: CCO:P0002599 ! regulation of transcriptional preinitiation complex assembly is_a: CCO:P0002628 ! positive regulation of transcription from RNA polymerase II promoter is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis relationship: positively_regulates CCO:P0003028 ! transcriptional preinitiation complex assembly [Term] id: CCO:P0002601 name: negative regulation of translational elongation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of translational elongation." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of translational elongation" EXACT [] synonym: "down-regulation of translational elongation" EXACT [] synonym: "downregulation of translational elongation" EXACT [] synonym: "inhibition of translational elongation" NARROW [] xref: GO:0045900 is_a: CCO:P0000663 ! regulation of translational elongation is_a: CCO:P0001135 ! negative regulation of translation relationship: has_participant CCO:B0051561 ! Q659G3_HUMAN relationship: has_participant CCO:B0051562 ! SRP09_HUMAN relationship: has_participant CCO:B0051564 ! Q6NVX0_HUMAN relationship: has_participant CCO:B0055316 ! SRP14_HUMAN [Term] id: CCO:P0002602 name: positive regulation of translational elongation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational elongation." [GOC:go_curators] subset: gosubset_prok synonym: "activation of translational elongation" NARROW [] synonym: "stimulation of translational elongation" NARROW [] synonym: "up regulation of translational elongation" EXACT [] synonym: "up-regulation of translational elongation" EXACT [] synonym: "upregulation of translational elongation" EXACT [] xref: GO:0045901 is_a: CCO:P0000663 ! regulation of translational elongation is_a: CCO:P0002524 ! positive regulation of translation [Term] id: CCO:P0002603 name: negative regulation of translational fidelity namespace: biological_process def: "Any process that decreases the ability of the translational apparatus to interpret the genetic code." [GOC:dph, GOC:tb] subset: gosubset_prok synonym: "down regulation of translational fidelity" EXACT [] synonym: "down-regulation of translational fidelity" EXACT [] synonym: "downregulation of translational fidelity" EXACT [] synonym: "inhibition of translational fidelity" NARROW [] xref: GO:0045902 is_a: CCO:P0000665 ! regulation of translational fidelity is_a: CCO:P0001135 ! negative regulation of translation [Term] id: CCO:P0002604 name: positive regulation of translational fidelity namespace: biological_process def: "Any process that increases the ability of the translational apparatus to interpret the genetic code." [GOC:dph, GOC:tb] subset: gosubset_prok synonym: "activation of translational fidelity" NARROW [] synonym: "stimulation of translational fidelity" NARROW [] synonym: "up regulation of translational fidelity" EXACT [] synonym: "up-regulation of translational fidelity" EXACT [] synonym: "upregulation of translational fidelity" EXACT [] xref: GO:0045903 is_a: CCO:P0000665 ! regulation of translational fidelity is_a: CCO:P0002524 ! positive regulation of translation [Term] id: CCO:P0002605 name: negative regulation of translational termination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of translational termination." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of translational termination" EXACT [] synonym: "down-regulation of translational termination" EXACT [] synonym: "downregulation of translational termination" EXACT [] synonym: "inhibition of translational termination" NARROW [] xref: GO:0045904 is_a: CCO:P0000664 ! regulation of translational termination is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0002173 ! negative regulation of protein complex disassembly [Term] id: CCO:P0002606 name: positive regulation of translational termination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational termination." [GOC:go_curators] subset: gosubset_prok synonym: "activation of translational termination" NARROW [] synonym: "stimulation of translational termination" NARROW [] synonym: "up regulation of translational termination" EXACT [] synonym: "up-regulation of translational termination" EXACT [] synonym: "upregulation of translational termination" EXACT [] xref: GO:0045905 is_a: CCO:P0000664 ! regulation of translational termination is_a: CCO:P0002174 ! positive regulation of protein complex disassembly is_a: CCO:P0002524 ! positive regulation of translation [Term] id: CCO:P0002607 name: negative regulation of DNA recombination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombination." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of DNA recombination" EXACT [] synonym: "down-regulation of DNA recombination" EXACT [] synonym: "downregulation of DNA recombination" EXACT [] synonym: "inhibition of DNA recombination" NARROW [] xref: GO:0045910 is_a: CCO:P0000398 ! regulation of DNA recombination is_a: CCO:P0003016 ! negative regulation of DNA metabolic process relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:P0002608 name: positive regulation of DNA recombination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA recombination." [GOC:go_curators] subset: gosubset_prok synonym: "activation of DNA recombination" NARROW [] synonym: "stimulation of DNA recombination" NARROW [] synonym: "up regulation of DNA recombination" EXACT [] synonym: "up-regulation of DNA recombination" EXACT [] synonym: "upregulation of DNA recombination" EXACT [] xref: GO:0045911 is_a: CCO:P0000398 ! regulation of DNA recombination is_a: CCO:P0003017 ! positive regulation of DNA metabolic process [Term] id: CCO:P0002609 name: negative regulation of catecholamine metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of catecholamine metabolic process" EXACT [] synonym: "down-regulation of catecholamine metabolic process" EXACT [] synonym: "downregulation of catecholamine metabolic process" EXACT [] synonym: "inhibition of catecholamine metabolic process" NARROW [] synonym: "negative regulation of catecholamine metabolism" EXACT [] xref: GO:0045914 is_a: CCO:P0001818 ! negative regulation of amine metabolic process is_a: CCO:P0002037 ! regulation of catecholamine metabolic process [Term] id: CCO:P0002610 name: positive regulation of catecholamine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] subset: gosubset_prok synonym: "activation of catecholamine metabolic process" NARROW [] synonym: "positive regulation of catecholamine metabolism" EXACT [] synonym: "stimulation of catecholamine metabolic process" NARROW [] synonym: "up regulation of catecholamine metabolic process" EXACT [] synonym: "up-regulation of catecholamine metabolic process" EXACT [] synonym: "upregulation of catecholamine metabolic process" EXACT [] xref: GO:0045915 is_a: CCO:P0001819 ! positive regulation of amine metabolic process is_a: CCO:P0002037 ! regulation of catecholamine metabolic process [Term] id: CCO:P0002611 name: negative regulation of complement activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of complement activation." [GOC:go_curators] synonym: "down regulation of complement activation" EXACT [] synonym: "down-regulation of complement activation" EXACT [] synonym: "downregulation of complement activation" EXACT [] synonym: "inhibition of complement activation" NARROW [] xref: GO:0045916 is_a: CCO:P0001263 ! regulation of complement activation is_a: CCO:P0002578 ! negative regulation of proteolysis [Term] id: CCO:P0002612 name: positive regulation of complement activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of complement activation." [GOC:go_curators] synonym: "activation of complement activation" NARROW [] synonym: "stimulation of complement activation" NARROW [] synonym: "up regulation of complement activation" EXACT [] synonym: "up-regulation of complement activation" EXACT [] synonym: "upregulation of complement activation" EXACT [] xref: GO:0045917 is_a: CCO:P0001263 ! regulation of complement activation is_a: CCO:P0002579 ! positive regulation of proteolysis [Term] id: CCO:P0002613 name: negative regulation of cytolysis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytolysis." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of cytolysis" EXACT [] synonym: "down-regulation of cytolysis" EXACT [] synonym: "downregulation of cytolysis" EXACT [] synonym: "inhibition of cytolysis" NARROW [] xref: GO:0045918 is_a: CCO:P0002051 ! regulation of cytolysis is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0002614 name: positive regulation of cytolysis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytolysis." [GOC:go_curators] subset: gosubset_prok synonym: "activation of cytolysis" NARROW [] synonym: "stimulation of cytolysis" NARROW [] synonym: "up regulation of cytolysis" EXACT [] synonym: "up-regulation of cytolysis" EXACT [] synonym: "upregulation of cytolysis" EXACT [] xref: GO:0045919 is_a: CCO:P0002051 ! regulation of cytolysis is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0057119 ! RRAGA_HUMAN relationship: has_participant CCO:B0058424 ! P2RX7_HUMAN [Term] id: CCO:P0002615 name: negative regulation of fatty acid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of fatty acid metabolic process" EXACT [] synonym: "down-regulation of fatty acid metabolic process" EXACT [] synonym: "downregulation of fatty acid metabolic process" EXACT [] synonym: "inhibition of fatty acid metabolic process" NARROW [] synonym: "negative regulation of fatty acid metabolism" EXACT [] xref: GO:0045922 is_a: CCO:P0001140 ! regulation of fatty acid metabolic process is_a: CCO:P0001405 ! negative regulation of cellular metabolic process relationship: has_participant CCO:B0054852 ! INS_HUMAN [Term] id: CCO:P0002616 name: positive regulation of fatty acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids." [GOC:go_curators] subset: gosubset_prok synonym: "activation of fatty acid metabolic process" NARROW [] synonym: "positive regulation of fatty acid metabolism" EXACT [] synonym: "stimulation of fatty acid metabolic process" NARROW [] synonym: "up regulation of fatty acid metabolic process" EXACT [] synonym: "up-regulation of fatty acid metabolic process" EXACT [] synonym: "upregulation of fatty acid metabolic process" EXACT [] xref: GO:0045923 is_a: CCO:P0001140 ! regulation of fatty acid metabolic process is_a: CCO:P0001406 ! positive regulation of cellular metabolic process relationship: has_participant CCO:B0056116 ! ADIPO_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN [Term] id: CCO:P0002617 name: negative regulation of juvenile hormone metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators] synonym: "down regulation of juvenile hormone metabolic process" EXACT [] synonym: "down-regulation of juvenile hormone metabolic process" EXACT [] synonym: "downregulation of juvenile hormone metabolic process" EXACT [] synonym: "inhibition of juvenile hormone metabolic process" NARROW [] synonym: "negative regulation of juvenile hormone metabolism" EXACT [] xref: GO:0045928 is_a: CCO:P0000807 ! regulation of juvenile hormone metabolic process is_a: CCO:P0001609 ! negative regulation of hormone metabolic process is_a: CCO:P0002570 ! negative regulation of isoprenoid metabolic process [Term] id: CCO:P0002618 name: positive regulation of juvenile hormone metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone." [GOC:go_curators] synonym: "activation of juvenile hormone metabolic process" NARROW [] synonym: "positive regulation of juvenile hormone metabolism" EXACT [] synonym: "stimulation of juvenile hormone metabolic process" NARROW [] synonym: "up regulation of juvenile hormone metabolic process" EXACT [] synonym: "up-regulation of juvenile hormone metabolic process" EXACT [] synonym: "upregulation of juvenile hormone metabolic process" EXACT [] xref: GO:0045929 is_a: CCO:P0000807 ! regulation of juvenile hormone metabolic process is_a: CCO:P0001610 ! positive regulation of hormone metabolic process is_a: CCO:P0002571 ! positive regulation of isoprenoid metabolic process [Term] id: CCO:P0002619 name: negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] xref: GO:0045934 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0001405 ! negative regulation of cellular metabolic process [Term] id: CCO:P0002620 name: positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] subset: gosubset_prok synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] xref: GO:0045935 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0001406 ! positive regulation of cellular metabolic process [Term] id: CCO:P0002621 name: negative regulation of phosphate metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of phosphate metabolic process" EXACT [] synonym: "down-regulation of phosphate metabolic process" EXACT [] synonym: "downregulation of phosphate metabolic process" EXACT [] synonym: "inhibition of phosphate metabolic process" NARROW [] synonym: "negative regulation of phosphate metabolism" EXACT [] xref: GO:0045936 is_a: CCO:P0000986 ! negative regulation of phosphorus metabolic process is_a: CCO:P0001143 ! regulation of phosphate metabolic process [Term] id: CCO:P0002622 name: positive regulation of phosphate metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] subset: gosubset_prok synonym: "activation of phosphate metabolic process" NARROW [] synonym: "positive regulation of phosphate metabolism" EXACT [] synonym: "stimulation of phosphate metabolic process" NARROW [] synonym: "up regulation of phosphate metabolic process" EXACT [] synonym: "up-regulation of phosphate metabolic process" EXACT [] synonym: "upregulation of phosphate metabolic process" EXACT [] xref: GO:0045937 is_a: CCO:P0000985 ! positive regulation of phosphorus metabolic process is_a: CCO:P0001143 ! regulation of phosphate metabolic process [Term] id: CCO:P0002623 name: negative regulation of steroid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of steroid metabolic process" EXACT [] synonym: "down-regulation of steroid metabolic process" EXACT [] synonym: "downregulation of steroid metabolic process" EXACT [] synonym: "inhibition of steroid metabolic process" NARROW [] synonym: "negative regulation of steroid metabolism" EXACT [] xref: GO:0045939 is_a: CCO:P0001141 ! regulation of steroid metabolic process is_a: CCO:P0001405 ! negative regulation of cellular metabolic process [Term] id: CCO:P0002624 name: positive regulation of steroid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] subset: gosubset_prok synonym: "activation of steroid metabolic process" NARROW [] synonym: "positive regulation of steroid metabolism" EXACT [] synonym: "stimulation of steroid metabolic process" NARROW [] synonym: "up regulation of steroid metabolic process" EXACT [] synonym: "up-regulation of steroid metabolic process" EXACT [] synonym: "upregulation of steroid metabolic process" EXACT [] xref: GO:0045940 is_a: CCO:P0001141 ! regulation of steroid metabolic process is_a: CCO:P0001406 ! positive regulation of cellular metabolic process [Term] id: CCO:P0002625 name: positive regulation of transcription namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription." [GOC:go_curators] subset: gosubset_prok synonym: "activation of transcription" NARROW [] synonym: "stimulation of transcription" NARROW [] synonym: "up regulation of transcription" EXACT [] synonym: "up-regulation of transcription" EXACT [] synonym: "upregulation of transcription" EXACT [] xref: GO:0045941 xref: Reactome:163765 xref: Reactome:211800 xref: Reactome:221564 xref: Reactome:230170 xref: Reactome:238201 xref: Reactome:244782 xref: Reactome:249686 xref: Reactome:252601 xref: Reactome:255788 xref: Reactome:259182 xref: Reactome:262538 xref: Reactome:265363 xref: Reactome:268491 xref: Reactome:274218 xref: Reactome:280687 xref: Reactome:282896 xref: Reactome:286706 xref: Reactome:288369 xref: Reactome:289870 xref: Reactome:290405 xref: Reactome:291788 xref: Reactome:292436 xref: Reactome:293769 is_a: CCO:P0001018 ! positive regulation of gene expression is_a: CCO:P0002369 ! regulation of transcription is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0001531 ! BMP7_HUMAN relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001594 ! DDIT3_HUMAN relationship: has_participant CCO:B0001720 ! ACVR1_HUMAN relationship: has_participant CCO:B0002019 ! PCAF_HUMAN relationship: has_participant CCO:B0002091 ! CITE2_HUMAN relationship: has_participant CCO:B0002202 ! SRTD1_HUMAN relationship: has_participant CCO:B0005339 ! CBP_HUMAN relationship: has_participant CCO:B0005354 ! T2FA_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005514 ! CEBPB_HUMAN relationship: has_participant CCO:B0005782 ! MED7_HUMAN relationship: has_participant CCO:B0006008 ! HNF1A_HUMAN relationship: has_participant CCO:B0006030 ! COE1_HUMAN relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0006033 ! ARNT2_HUMAN relationship: has_participant CCO:B0017118 ! ING2_HUMAN relationship: has_participant CCO:B0017844 ! TGFI1_HUMAN relationship: has_participant CCO:B0017927 ! MYST3_HUMAN relationship: has_participant CCO:B0017931 ! MYST4_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0020930 ! GLIS2_HUMAN relationship: has_participant CCO:B0021707 ! CITE4_HUMAN relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0024005 ! UBP22_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0041239 ! PSMD9_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: has_participant CCO:B0050546 ! TF3B_HUMAN relationship: has_participant CCO:B0051010 ! SPT4H_HUMAN relationship: has_participant CCO:B0054376 ! GDF8_HUMAN relationship: has_participant CCO:B0055082 ! HMGA1_HUMAN relationship: has_participant CCO:B0055100 ! EGR1_HUMAN relationship: has_participant CCO:B0055110 ! NFKB1_HUMAN relationship: has_participant CCO:B0055156 ! MYF6_HUMAN relationship: has_participant CCO:B0055268 ! CD80_HUMAN relationship: has_participant CCO:B0055299 ! HNF1B_HUMAN relationship: has_participant CCO:B0055334 ! ETV5_HUMAN relationship: has_participant CCO:B0055346 ! CD86_HUMAN relationship: has_participant CCO:B0055362 ! ETV4_HUMAN relationship: has_participant CCO:B0055369 ! GATA4_HUMAN relationship: has_participant CCO:B0055412 ! TNNI2_HUMAN relationship: has_participant CCO:B0055471 ! IRAK1_HUMAN relationship: has_participant CCO:B0055611 ! PHS_HUMAN relationship: has_participant CCO:B0055768 ! MEF2C_HUMAN relationship: has_participant CCO:B0055786 ! PPARA_HUMAN relationship: has_participant CCO:B0055888 ! Q13222_HUMAN relationship: has_participant CCO:B0055911 ! NFAC2_HUMAN relationship: has_participant CCO:B0055950 ! KLF5_HUMAN relationship: has_participant CCO:B0056056 ! IRF4_HUMAN relationship: has_participant CCO:B0056112 ! NCOA1_HUMAN relationship: has_participant CCO:B0056136 ! Q16365_HUMAN relationship: has_participant CCO:B0056205 ! ZN423_HUMAN relationship: has_participant CCO:B0056350 ! Q53EU2_HUMAN relationship: has_participant CCO:B0056564 ! ZEP3_HUMAN relationship: has_participant CCO:B0056834 ! GDF6_HUMAN relationship: has_participant CCO:B0056863 ! RGMB_HUMAN relationship: has_participant CCO:B0056941 ! SMRD3_HUMAN relationship: has_participant CCO:B0057080 ! Q6ZV39_HUMAN relationship: has_participant CCO:B0057127 ! PTF1A_HUMAN relationship: has_participant CCO:B0057317 ! IL29_HUMAN relationship: has_participant CCO:B0057384 ! YAF2_HUMAN relationship: has_participant CCO:B0057419 ! ABRA_HUMAN relationship: has_participant CCO:B0057531 ! Q8N950_HUMAN relationship: has_participant CCO:B0057980 ! CHUR_HUMAN relationship: has_participant CCO:B0058383 ! KKCC2_HUMAN relationship: has_participant CCO:B0058411 ! Q99419_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: has_participant CCO:B0058543 ! GATA5_HUMAN relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN relationship: has_participant CCO:B0058717 ! SMRCD_HUMAN relationship: has_participant CCO:B0058748 ! MYST1_HUMAN relationship: has_participant CCO:B0058790 ! ZN287_HUMAN relationship: has_participant CCO:B0059164 ! SIX4_HUMAN relationship: has_participant CCO:B0059180 ! SRTD3_HUMAN relationship: has_participant CCO:B0059181 ! GDF2_HUMAN relationship: has_participant CCO:B0059357 ! JHD2A_HUMAN relationship: has_participant CCO:B0059388 ! KLF2_HUMAN [Term] id: CCO:P0002626 name: negative regulation of phosphorus utilization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphorus utilization." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of phosphorus utilization" EXACT [] synonym: "down-regulation of phosphorus utilization" EXACT [] synonym: "downregulation of phosphorus utilization" EXACT [] synonym: "inhibition of phosphorus utilization" NARROW [] xref: GO:0045942 is_a: CCO:P0000670 ! regulation of phosphorus utilization is_a: CCO:P0000986 ! negative regulation of phosphorus metabolic process [Term] id: CCO:P0002627 name: positive regulation of transcription from RNA polymerase I promoter namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase I promoter." [GOC:go_curators] synonym: "activation of transcription from RNA polymerase I promoter" NARROW [] synonym: "positive regulation of transcription from Pol I promoter" EXACT [] synonym: "stimulation of transcription from RNA polymerase I promoter" NARROW [] synonym: "up regulation of transcription from RNA polymerase I promoter" EXACT [] synonym: "up-regulation of transcription from RNA polymerase I promoter" EXACT [] synonym: "upregulation of transcription from RNA polymerase I promoter" EXACT [] xref: GO:0045943 is_a: CCO:P0000656 ! regulation of transcription from RNA polymerase I promoter is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:P0002628 name: positive regulation of transcription from RNA polymerase II promoter namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase II promoter." [GOC:go_curators] synonym: "activation of transcription from RNA polymerase II promoter" NARROW [] synonym: "positive regulation of transcription from Pol II promoter" EXACT [] synonym: "stimulation of transcription from RNA polymerase II promoter" NARROW [] synonym: "up regulation of transcription from RNA polymerase II promoter" EXACT [] synonym: "up-regulation of transcription from RNA polymerase II promoter" EXACT [] synonym: "upregulation of transcription from RNA polymerase II promoter" EXACT [] xref: GO:0045944 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: has_participant CCO:B0001345 ! SPT5H_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001483 ! P53_HUMAN relationship: has_participant CCO:B0001487 ! JUN_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0001510 ! IRF1_HUMAN relationship: has_participant CCO:B0001585 ! TF2H1_HUMAN relationship: has_participant CCO:B0001609 ! STA5A_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001651 ! STA5B_HUMAN relationship: has_participant CCO:B0001652 ! CCNH_HUMAN relationship: has_participant CCO:B0001653 ! MAT1_HUMAN relationship: has_participant CCO:B0001713 ! E2F1_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0002231 ! PLAL1_HUMAN relationship: has_participant CCO:B0005218 ! ZMIZ2_HUMAN relationship: has_participant CCO:B0005322 ! SMAD4_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0005369 ! EPC1_HUMAN relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005513 ! BCL3_HUMAN relationship: has_participant CCO:B0005534 ! TNR1A_HUMAN relationship: has_participant CCO:B0005616 ! PPARG_HUMAN relationship: has_participant CCO:B0005637 ! ELK1_HUMAN relationship: has_participant CCO:B0005783 ! MED21_HUMAN relationship: has_participant CCO:B0005785 ! MED17_HUMAN relationship: has_participant CCO:B0005786 ! MED1_HUMAN relationship: has_participant CCO:B0005789 ! MED12_HUMAN relationship: has_participant CCO:B0005792 ! MED6_HUMAN relationship: has_participant CCO:B0005794 ! MED13_HUMAN relationship: has_participant CCO:B0005800 ! MED14_HUMAN relationship: has_participant CCO:B0005893 ! NCOA6_HUMAN relationship: has_participant CCO:B0006027 ! ELF1_HUMAN relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0006033 ! ARNT2_HUMAN relationship: has_participant CCO:B0006077 ! EPAS1_HUMAN relationship: has_participant CCO:B0006261 ! MYO6_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0016733 ! FOXD3_HUMAN relationship: has_participant CCO:B0016798 ! PLAL2_HUMAN relationship: has_participant CCO:B0016881 ! FOXO1_HUMAN relationship: has_participant CCO:B0019067 ! RORA_HUMAN relationship: has_participant CCO:B0020283 ! SOX15_HUMAN relationship: has_participant CCO:B0020295 ! SOX2_HUMAN relationship: has_participant CCO:B0020932 ! GLIS1_HUMAN relationship: has_participant CCO:B0021435 ! ATF4_HUMAN relationship: has_participant CCO:B0024886 ! RXRA_HUMAN relationship: has_participant CCO:B0026248 ! ERCC2_HUMAN relationship: has_participant CCO:B0026530 ! NPAS2_HUMAN relationship: has_participant CCO:B0026531 ! CLOCK_HUMAN relationship: has_participant CCO:B0028347 ! SRF_HUMAN relationship: has_participant CCO:B0028502 ! ERCC3_HUMAN relationship: has_participant CCO:B0029685 ! STAT6_HUMAN relationship: has_participant CCO:B0030506 ! NGN2_HUMAN relationship: has_participant CCO:B0030509 ! NGN3_HUMAN relationship: has_participant CCO:B0031624 ! FOXA1_HUMAN relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0032261 ! TEAD3_HUMAN relationship: has_participant CCO:B0032268 ! TEAD2_HUMAN relationship: has_participant CCO:B0033619 ! RUNX1_HUMAN relationship: has_participant CCO:B0033733 ! MAFB_HUMAN relationship: has_participant CCO:B0034126 ! RARG_HUMAN relationship: has_participant CCO:B0036805 ! PDX1_HUMAN relationship: has_participant CCO:B0036810 ! GSX1_HUMAN relationship: has_participant CCO:B0036934 ! HNF4A_HUMAN relationship: has_participant CCO:B0037982 ! DLX2_HUMAN relationship: has_participant CCO:B0042130 ! BMP6_HUMAN relationship: has_participant CCO:B0043733 ! TTF1_HUMAN relationship: has_participant CCO:B0043826 ! SMAD3_HUMAN relationship: has_participant CCO:B0048652 ! PIT1_HUMAN relationship: has_participant CCO:B0050345 ! FOXO3_HUMAN relationship: has_participant CCO:B0050528 ! CNOT7_HUMAN relationship: has_participant CCO:B0051010 ! SPT4H_HUMAN relationship: has_participant CCO:B0054311 ! BMAL1_HUMAN relationship: has_participant CCO:B0054456 ! CRX_HUMAN relationship: has_participant CCO:B0054622 ! PROP1_HUMAN relationship: has_participant CCO:B0054655 ! FOXH1_HUMAN relationship: has_participant CCO:B0054698 ! MTA2_HUMAN relationship: has_participant CCO:B0054708 ! PRP6_HUMAN relationship: has_participant CCO:B0054723 ! NKX22_HUMAN relationship: has_participant CCO:B0054819 ! HAND1_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054914 ! ADRB2_HUMAN relationship: has_participant CCO:B0054922 ! GLI1_HUMAN relationship: has_participant CCO:B0054965 ! GLI2_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN relationship: has_participant CCO:B0055031 ! MYOG_HUMAN relationship: has_participant CCO:B0055100 ! EGR1_HUMAN relationship: has_participant CCO:B0055126 ! IL11_HUMAN relationship: has_participant CCO:B0055243 ! TLX1_HUMAN relationship: has_participant CCO:B0055363 ! NR4A2_HUMAN relationship: has_participant CCO:B0055370 ! NKX21_HUMAN relationship: has_participant CCO:B0055381 ! YAP1_HUMAN relationship: has_participant CCO:B0055403 ! SOX9_HUMAN relationship: has_participant CCO:B0055407 ! NRIP1_HUMAN relationship: has_participant CCO:B0055506 ! NKX25_HUMAN relationship: has_participant CCO:B0055547 ! SOX10_HUMAN relationship: has_participant CCO:B0055557 ! SOX8_HUMAN relationship: has_participant CCO:B0055744 ! NMDZ1_HUMAN relationship: has_participant CCO:B0055768 ! MEF2C_HUMAN relationship: has_participant CCO:B0055786 ! PPARA_HUMAN relationship: has_participant CCO:B0055835 ! TEF_HUMAN relationship: has_participant CCO:B0055918 ! SQSTM_HUMAN relationship: has_participant CCO:B0055929 ! NDF1_HUMAN relationship: has_participant CCO:B0056004 ! IHH_HUMAN relationship: has_participant CCO:B0056066 ! SHH_HUMAN relationship: has_participant CCO:B0056076 ! NCOA2_HUMAN relationship: has_participant CCO:B0056113 ! SMAD2_HUMAN relationship: has_participant CCO:B0056114 ! SMAD1_HUMAN relationship: has_participant CCO:B0056565 ! UTF1_HUMAN relationship: has_participant CCO:B0056949 ! CRTC1_HUMAN relationship: has_participant CCO:B0057126 ! BHLH8_HUMAN relationship: has_participant CCO:B0057308 ! PRGC2_HUMAN relationship: has_participant CCO:B0057409 ! MAML2_HUMAN relationship: has_participant CCO:B0057419 ! ABRA_HUMAN relationship: has_participant CCO:B0057549 ! ZBT38_HUMAN relationship: has_participant CCO:B0057586 ! BHLH4_HUMAN relationship: has_participant CCO:B0057889 ! Q8TAL0_HUMAN relationship: has_participant CCO:B0058046 ! CSRN3_HUMAN relationship: has_participant CCO:B0058068 ! MAML1_HUMAN relationship: has_participant CCO:B0058108 ! ATOH1_HUMAN relationship: has_participant CCO:B0058242 ! MAML3_HUMAN relationship: has_participant CCO:B0058337 ! RBM14_HUMAN relationship: has_participant CCO:B0058387 ! AXUD1_HUMAN relationship: has_participant CCO:B0058430 ! ELF4_HUMAN relationship: has_participant CCO:B0058446 ! SMAD5_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058638 ! WWTR1_HUMAN relationship: has_participant CCO:B0058661 ! CSRN2_HUMAN relationship: has_participant CCO:B0058823 ! SRA1_HUMAN relationship: has_participant CCO:B0059143 ! NUFP1_HUMAN relationship: has_participant CCO:B0059175 ! LEF1_HUMAN relationship: has_participant CCO:B0059226 ! MKL2_HUMAN relationship: has_participant CCO:B0059320 ! TR150_HUMAN relationship: has_participant CCO:B0059326 ! KLF13_HUMAN [Term] id: CCO:P0002629 name: positive regulation of transcription from RNA polymerase III promoter namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription from the RNA polymerase III promoter." [GOC:go_curators] synonym: "activation of transcription from RNA polymerase III promoter" NARROW [] synonym: "positive regulation of transcription from Pol III promoter" EXACT [] synonym: "stimulation of transcription from RNA polymerase III promoter" NARROW [] synonym: "up regulation of transcription from RNA polymerase III promoter" EXACT [] synonym: "up-regulation of transcription from RNA polymerase III promoter" EXACT [] synonym: "upregulation of transcription from RNA polymerase III promoter" EXACT [] xref: GO:0045945 is_a: CCO:P0000659 ! regulation of transcription from RNA polymerase III promoter is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent [Term] id: CCO:P0002630 name: negative regulation of translational initiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of translational initiation." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of translational initiation" EXACT [] synonym: "down-regulation of translational initiation" EXACT [] synonym: "downregulation of translational initiation" EXACT [] synonym: "inhibition of translational initiation" NARROW [] xref: GO:0045947 is_a: CCO:P0000661 ! regulation of translational initiation is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0054565 ! 4EBP3_HUMAN relationship: has_participant CCO:B0055927 ! 4EBP1_HUMAN relationship: has_participant CCO:B0055928 ! 4EBP2_HUMAN relationship: has_participant CCO:B0058473 ! PAIP2_HUMAN relationship: has_participant CCO:B0059232 ! PAI2B_HUMAN [Term] id: CCO:P0002631 name: positive regulation of translational initiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational initiation." [GOC:go_curators] subset: gosubset_prok synonym: "activation of translational initiation" NARROW [] synonym: "stimulation of translational initiation" NARROW [] synonym: "up regulation of translational initiation" EXACT [] synonym: "up-regulation of translational initiation" EXACT [] synonym: "upregulation of translational initiation" EXACT [] xref: GO:0045948 is_a: CCO:P0000661 ! regulation of translational initiation is_a: CCO:P0002524 ! positive regulation of translation is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0001972 ! BOLL_HUMAN relationship: has_participant CCO:B0005886 ! DAZ1_HUMAN relationship: has_participant CCO:B0036567 ! IF5A1_HUMAN relationship: has_participant CCO:B0055879 ! EI2BE_HUMAN relationship: has_participant CCO:B0058111 ! DAZL_HUMAN [Term] id: CCO:P0002632 name: positive regulation of phosphorus utilization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phosphorus utilization." [GOC:go_curators] subset: gosubset_prok synonym: "activation of phosphorus utilization" NARROW [] synonym: "stimulation of phosphorus utilization" NARROW [] synonym: "up regulation of phosphorus utilization" EXACT [] synonym: "up-regulation of phosphorus utilization" EXACT [] synonym: "upregulation of phosphorus utilization" EXACT [] xref: GO:0045949 is_a: CCO:P0000670 ! regulation of phosphorus utilization is_a: CCO:P0000985 ! positive regulation of phosphorus metabolic process [Term] id: CCO:P0002633 name: negative regulation of mitotic recombination namespace: biological_process def: "Any process that inhibits or decreases the rate of DNA recombination during mitosis." [GOC:go_curators, GOC:hjd] synonym: "down regulation of mitotic recombination" EXACT [] synonym: "down-regulation of mitotic recombination" EXACT [] synonym: "downregulation of mitotic recombination" EXACT [] synonym: "inhibition of mitotic recombination" NARROW [] synonym: "negative regulation of recombination within rDNA repeats" NARROW [] xref: GO:0045950 is_a: CCO:P0000399 ! regulation of mitotic recombination is_a: CCO:P0002607 ! negative regulation of DNA recombination relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:P0002634 name: positive regulation of mitotic recombination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis." [GOC:go_curators] synonym: "activation of mitotic recombination" NARROW [] synonym: "positive regulation of recombination within rDNA repeats" NARROW [] synonym: "stimulation of mitotic recombination" NARROW [] synonym: "up regulation of mitotic recombination" EXACT [] synonym: "up-regulation of mitotic recombination" EXACT [] synonym: "upregulation of mitotic recombination" EXACT [] xref: GO:0045951 is_a: CCO:P0000399 ! regulation of mitotic recombination is_a: CCO:P0002608 ! positive regulation of DNA recombination [Term] id: CCO:P0002635 name: regulation of juvenile hormone catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone." [GOC:go_curators] synonym: "regulation of juvenile hormone breakdown" EXACT [] synonym: "regulation of juvenile hormone catabolism" EXACT [] synonym: "regulation of juvenile hormone degradation" EXACT [] xref: GO:0045952 is_a: CCO:P0000807 ! regulation of juvenile hormone metabolic process is_a: CCO:P0001410 ! regulation of cellular catabolic process [Term] id: CCO:P0002636 name: negative regulation of natural killer cell mediated cytotoxicity namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "down regulation of natural killer cell mediated cytotoxicity" EXACT [] synonym: "down-regulation of natural killer cell mediated cytotoxicity" EXACT [] synonym: "downregulation of natural killer cell mediated cytotoxicity" EXACT [] synonym: "inhibition of natural killer cell mediated cytotoxicity" NARROW [] synonym: "negative regulation of natural killer cell mediated cell death" EXACT [] synonym: "negative regulation of natural killer cell mediated cell killing" EXACT [] synonym: "negative regulation of natural killer cell mediated cytolysis" RELATED [] synonym: "negative regulation of NK cell mediated cell death" EXACT [] synonym: "negative regulation of NK cell mediated cell killing" EXACT [] synonym: "negative regulation of NK cell mediated cytolysis" RELATED [] synonym: "negative regulation of NK cell mediated cytotoxicity" EXACT [] xref: GO:0045953 is_a: CCO:P0002052 ! regulation of natural killer cell mediated cytotoxicity relationship: negatively_regulates CCO:P0002050 ! natural killer cell mediated cytotoxicity [Term] id: CCO:P0002637 name: positive regulation of natural killer cell mediated cytotoxicity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity." [GOC:add, ISBN:0781735149 "Fundamental Immunology"] synonym: "activation of natural killer cell mediated cytotoxicity" NARROW [] synonym: "positive regulation of natural killer cell mediated cell death" EXACT [] synonym: "positive regulation of natural killer cell mediated cell killing" EXACT [] synonym: "positive regulation of natural killer cell mediated cytolysis" RELATED [] synonym: "positive regulation of NK cell mediated cell death" EXACT [] synonym: "positive regulation of NK cell mediated cell killing" EXACT [] synonym: "positive regulation of NK cell mediated cytolysis" RELATED [] synonym: "positive regulation of NK cell mediated cytotoxicity" EXACT [] synonym: "stimulation of natural killer cell mediated cytotoxicity" NARROW [] synonym: "up regulation of natural killer cell mediated cytotoxicity" EXACT [] synonym: "up-regulation of natural killer cell mediated cytotoxicity" EXACT [] synonym: "upregulation of natural killer cell mediated cytotoxicity" EXACT [] xref: GO:0045954 is_a: CCO:P0002052 ! regulation of natural killer cell mediated cytotoxicity relationship: has_participant CCO:B0002110 ! CADM1_HUMAN relationship: has_participant CCO:B0015065 ! CRTAM_HUMAN relationship: has_participant CCO:B0055103 ! LAG3_HUMAN relationship: has_participant CCO:B0055192 ! NKG2D_HUMAN relationship: positively_regulates CCO:P0002050 ! natural killer cell mediated cytotoxicity [Term] id: CCO:P0002638 name: negative regulation of complement activation, alternative pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of complement activation by the alternative pathway." [GOC:go_curators] synonym: "down regulation of complement activation, alternative pathway" EXACT [] synonym: "down-regulation of complement activation, alternative pathway" EXACT [] synonym: "downregulation of complement activation, alternative pathway" EXACT [] synonym: "inhibition of complement activation, alternative pathway" NARROW [] xref: GO:0045957 is_a: CCO:P0001265 ! regulation of complement activation, alternative pathway is_a: CCO:P0002611 ! negative regulation of complement activation [Term] id: CCO:P0002639 name: positive regulation of complement activation, alternative pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway." [GOC:go_curators] synonym: "activation of complement activation, alternative pathway" NARROW [] synonym: "stimulation of complement activation, alternative pathway" NARROW [] synonym: "up regulation of complement activation, alternative pathway" EXACT [] synonym: "up-regulation of complement activation, alternative pathway" EXACT [] synonym: "upregulation of complement activation, alternative pathway" EXACT [] xref: GO:0045958 is_a: CCO:P0001265 ! regulation of complement activation, alternative pathway is_a: CCO:P0002612 ! positive regulation of complement activation [Term] id: CCO:P0002640 name: negative regulation of complement activation, classical pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of complement activation by the classical pathway." [GOC:go_curators] synonym: "down regulation of complement activation, classical pathway" EXACT [] synonym: "down-regulation of complement activation, classical pathway" EXACT [] synonym: "downregulation of complement activation, classical pathway" EXACT [] synonym: "inhibition of complement activation, classical pathway" NARROW [] xref: GO:0045959 is_a: CCO:P0001264 ! regulation of complement activation, classical pathway is_a: CCO:P0002611 ! negative regulation of complement activation [Term] id: CCO:P0002641 name: positive regulation of complement activation, classical pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway." [GOC:go_curators] synonym: "activation of complement activation, classical pathway" NARROW [] synonym: "stimulation of complement activation, classical pathway" NARROW [] synonym: "up regulation of complement activation, classical pathway" EXACT [] synonym: "up-regulation of complement activation, classical pathway" EXACT [] synonym: "upregulation of complement activation, classical pathway" EXACT [] xref: GO:0045960 is_a: CCO:P0001264 ! regulation of complement activation, classical pathway is_a: CCO:P0002612 ! positive regulation of complement activation [Term] id: CCO:P0002642 name: negative regulation of dopamine metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine." [GOC:go_curators] synonym: "down regulation of dopamine metabolic process" EXACT [] synonym: "down-regulation of dopamine metabolic process" EXACT [] synonym: "downregulation of dopamine metabolic process" EXACT [] synonym: "inhibition of dopamine metabolic process" NARROW [] synonym: "negative regulation of dopamine metabolism" EXACT [] xref: GO:0045963 is_a: CCO:P0002032 ! regulation of dopamine metabolic process is_a: CCO:P0002609 ! negative regulation of catecholamine metabolic process [Term] id: CCO:P0002643 name: positive regulation of dopamine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine." [GOC:go_curators] synonym: "activation of dopamine metabolic process" NARROW [] synonym: "positive regulation of dopamine metabolism" EXACT [] synonym: "stimulation of dopamine metabolic process" NARROW [] synonym: "up regulation of dopamine metabolic process" EXACT [] synonym: "up-regulation of dopamine metabolic process" EXACT [] synonym: "upregulation of dopamine metabolic process" EXACT [] xref: GO:0045964 is_a: CCO:P0002032 ! regulation of dopamine metabolic process is_a: CCO:P0002610 ! positive regulation of catecholamine metabolic process relationship: has_participant CCO:B0036957 ! HPRT_HUMAN [Term] id: CCO:P0002644 name: negative regulation of ecdysteroid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids." [GOC:go_curators] synonym: "down regulation of ecdysteroid metabolic process" EXACT [] synonym: "down-regulation of ecdysteroid metabolic process" EXACT [] synonym: "downregulation of ecdysteroid metabolic process" EXACT [] synonym: "inhibition of ecdysteroid metabolic process" NARROW [] synonym: "negative regulation of ecdysteroid metabolism" EXACT [] xref: GO:0045965 is_a: CCO:P0000804 ! regulation of ecdysteroid metabolic process is_a: CCO:P0001609 ! negative regulation of hormone metabolic process is_a: CCO:P0002623 ! negative regulation of steroid metabolic process [Term] id: CCO:P0002645 name: positive regulation of ecdysteroid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids." [GOC:go_curators] synonym: "activation of ecdysteroid metabolic process" NARROW [] synonym: "positive regulation of ecdysteroid metabolism" EXACT [] synonym: "stimulation of ecdysteroid metabolic process" NARROW [] synonym: "up regulation of ecdysteroid metabolic process" EXACT [] synonym: "up-regulation of ecdysteroid metabolic process" EXACT [] synonym: "upregulation of ecdysteroid metabolic process" EXACT [] xref: GO:0045966 is_a: CCO:P0000804 ! regulation of ecdysteroid metabolic process is_a: CCO:P0001610 ! positive regulation of hormone metabolic process is_a: CCO:P0002624 ! positive regulation of steroid metabolic process [Term] id: CCO:P0002646 name: negative regulation of juvenile hormone biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone." [GOC:go_curators] synonym: "down regulation of juvenile hormone biosynthetic process" EXACT [] synonym: "down-regulation of juvenile hormone biosynthetic process" EXACT [] synonym: "downregulation of juvenile hormone biosynthetic process" EXACT [] synonym: "inhibition of juvenile hormone biosynthetic process" NARROW [] synonym: "negative regulation of juvenile hormone anabolism" EXACT [] synonym: "negative regulation of juvenile hormone biosynthesis" EXACT [] synonym: "negative regulation of juvenile hormone formation" EXACT [] synonym: "negative regulation of juvenile hormone synthesis" EXACT [] xref: GO:0045968 is_a: CCO:P0000808 ! regulation of juvenile hormone biosynthetic process is_a: CCO:P0001611 ! negative regulation of hormone biosynthetic process is_a: CCO:P0002617 ! negative regulation of juvenile hormone metabolic process [Term] id: CCO:P0002647 name: positive regulation of juvenile hormone biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone." [GOC:go_curators] synonym: "activation of juvenile hormone biosynthetic process" NARROW [] synonym: "positive regulation of juvenile hormone anabolism" EXACT [] synonym: "positive regulation of juvenile hormone biosynthesis" EXACT [] synonym: "positive regulation of juvenile hormone formation" EXACT [] synonym: "positive regulation of juvenile hormone synthesis" EXACT [] synonym: "stimulation of juvenile hormone biosynthetic process" NARROW [] synonym: "up regulation of juvenile hormone biosynthetic process" EXACT [] synonym: "up-regulation of juvenile hormone biosynthetic process" EXACT [] synonym: "upregulation of juvenile hormone biosynthetic process" EXACT [] xref: GO:0045969 is_a: CCO:P0000808 ! regulation of juvenile hormone biosynthetic process is_a: CCO:P0002618 ! positive regulation of juvenile hormone metabolic process is_a: CCO:P0002746 ! positive regulation of hormone biosynthetic process [Term] id: CCO:P0002648 name: negative regulation of juvenile hormone catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone." [GOC:go_curators] synonym: "down regulation of juvenile hormone catabolic process" EXACT [] synonym: "down-regulation of juvenile hormone catabolic process" EXACT [] synonym: "downregulation of juvenile hormone catabolic process" EXACT [] synonym: "inhibition of juvenile hormone catabolic process" NARROW [] synonym: "negative regulation of juvenile hormone breakdown" EXACT [] synonym: "negative regulation of juvenile hormone catabolism" EXACT [] synonym: "negative regulation of juvenile hormone degradation" EXACT [] xref: GO:0045970 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0002617 ! negative regulation of juvenile hormone metabolic process is_a: CCO:P0002635 ! regulation of juvenile hormone catabolic process [Term] id: CCO:P0002649 name: positive regulation of juvenile hormone catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone." [GOC:go_curators] synonym: "activation of juvenile hormone catabolic process" NARROW [] synonym: "positive regulation of juvenile hormone breakdown" EXACT [] synonym: "positive regulation of juvenile hormone catabolism" EXACT [] synonym: "positive regulation of juvenile hormone degradation" EXACT [] synonym: "stimulation of juvenile hormone catabolic process" NARROW [] synonym: "up regulation of juvenile hormone catabolic process" EXACT [] synonym: "up-regulation of juvenile hormone catabolic process" EXACT [] synonym: "upregulation of juvenile hormone catabolic process" EXACT [] xref: GO:0045971 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0002618 ! positive regulation of juvenile hormone metabolic process is_a: CCO:P0002635 ! regulation of juvenile hormone catabolic process [Term] id: CCO:P0002650 name: negative regulation of juvenile hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of juvenile hormone." [GOC:go_curators] synonym: "down regulation of juvenile hormone secretion" EXACT [] synonym: "down-regulation of juvenile hormone secretion" EXACT [] synonym: "downregulation of juvenile hormone secretion" EXACT [] synonym: "inhibition of juvenile hormone secretion" NARROW [] xref: GO:0045972 is_a: CCO:P0000809 ! regulation of juvenile hormone secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0002651 name: positive regulation of juvenile hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone." [GOC:go_curators] synonym: "activation of juvenile hormone secretion" NARROW [] synonym: "stimulation of juvenile hormone secretion" NARROW [] synonym: "up regulation of juvenile hormone secretion" EXACT [] synonym: "up-regulation of juvenile hormone secretion" EXACT [] synonym: "upregulation of juvenile hormone secretion" EXACT [] xref: GO:0045973 is_a: CCO:P0000809 ! regulation of juvenile hormone secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion [Term] id: CCO:P0002652 name: regulation of translation, ncRNA-mediated namespace: biological_process def: "Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein." [GOC:dph, GOC:go_curators, GOC:tb] xref: GO:0045974 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0002653 name: positive regulation of translation, ncRNA-mediated namespace: biological_process def: "Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of mRNA translation, ncRNA-mediated" NARROW [] synonym: "stimulation of mRNA translation, ncRNA-mediated" NARROW [] synonym: "up regulation of mRNA translation, ncRNA-mediated" EXACT [] synonym: "up-regulation of mRNA translation, ncRNA-mediated" EXACT [] synonym: "upregulation of mRNA translation, ncRNA-mediated" EXACT [] xref: GO:0045975 is_a: CCO:P0002524 ! positive regulation of translation is_a: CCO:P0002652 ! regulation of translation, ncRNA-mediated [Term] id: CCO:P0002654 name: negative regulation of nucleoside metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of nucleoside metabolic process" EXACT [] synonym: "down-regulation of nucleoside metabolic process" EXACT [] synonym: "downregulation of nucleoside metabolic process" EXACT [] synonym: "inhibition of nucleoside metabolic process" NARROW [] synonym: "negative regulation of nucleoside metabolism" EXACT [] xref: GO:0045978 is_a: CCO:P0000847 ! regulation of nucleoside metabolic process is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0002655 name: positive regulation of nucleoside metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides." [GOC:go_curators] subset: gosubset_prok synonym: "activation of nucleoside metabolic process" NARROW [] synonym: "positive regulation of nucleoside metabolism" EXACT [] synonym: "stimulation of nucleoside metabolic process" NARROW [] synonym: "up regulation of nucleoside metabolic process" EXACT [] synonym: "up-regulation of nucleoside metabolic process" EXACT [] synonym: "upregulation of nucleoside metabolic process" EXACT [] xref: GO:0045979 is_a: CCO:P0000847 ! regulation of nucleoside metabolic process is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0002656 name: negative regulation of nucleotide metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of nucleotide metabolic process" EXACT [] synonym: "down-regulation of nucleotide metabolic process" EXACT [] synonym: "downregulation of nucleotide metabolic process" EXACT [] synonym: "inhibition of nucleotide metabolic process" NARROW [] synonym: "negative regulation of nucleotide metabolism" EXACT [] xref: GO:0045980 is_a: CCO:P0000625 ! regulation of nucleotide metabolic process is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process relationship: has_participant CCO:B0031622 ! CDD_HUMAN relationship: has_participant CCO:B0053804 ! A6NE74_HUMAN relationship: has_participant CCO:B0056499 ! Q5JXL8_HUMAN [Term] id: CCO:P0002657 name: positive regulation of nucleotide metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides." [GOC:go_curators] subset: gosubset_prok synonym: "activation of nucleotide metabolic process" NARROW [] synonym: "positive regulation of nucleotide metabolism" EXACT [] synonym: "stimulation of nucleotide metabolic process" NARROW [] synonym: "up regulation of nucleotide metabolic process" EXACT [] synonym: "up-regulation of nucleotide metabolic process" EXACT [] synonym: "upregulation of nucleotide metabolic process" EXACT [] xref: GO:0045981 is_a: CCO:P0000625 ! regulation of nucleotide metabolic process is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0002658 name: negative regulation of purine base metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine bases." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of purine base metabolic process" EXACT [] synonym: "down-regulation of purine base metabolic process" EXACT [] synonym: "downregulation of purine base metabolic process" EXACT [] synonym: "inhibition of purine base metabolic process" NARROW [] synonym: "negative regulation of purine base metabolism" EXACT [] xref: GO:0045982 is_a: CCO:P0000626 ! regulation of purine base metabolic process is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0002659 name: positive regulation of purine base metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases." [GOC:go_curators] subset: gosubset_prok synonym: "activation of purine base metabolic process" NARROW [] synonym: "positive regulation of purine base metabolism" EXACT [] synonym: "stimulation of purine base metabolic process" NARROW [] synonym: "up regulation of purine base metabolic process" EXACT [] synonym: "up-regulation of purine base metabolic process" EXACT [] synonym: "upregulation of purine base metabolic process" EXACT [] xref: GO:0045983 is_a: CCO:P0000626 ! regulation of purine base metabolic process is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0002660 name: negative regulation of pyrimidine base metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine bases." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of pyrimidine base metabolic process" EXACT [] synonym: "down-regulation of pyrimidine base metabolic process" EXACT [] synonym: "downregulation of pyrimidine base metabolic process" EXACT [] synonym: "inhibition of pyrimidine base metabolic process" NARROW [] synonym: "negative regulation of pyrimidine base metabolism" EXACT [] xref: GO:0045984 is_a: CCO:P0000627 ! regulation of pyrimidine base metabolic process is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0002661 name: positive regulation of pyrimidine base metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine bases." [GOC:go_curators] subset: gosubset_prok synonym: "activation of pyrimidine base metabolic process" NARROW [] synonym: "positive regulation of pyrimidine base metabolism" EXACT [] synonym: "stimulation of pyrimidine base metabolic process" NARROW [] synonym: "up regulation of pyrimidine base metabolic process" EXACT [] synonym: "up-regulation of pyrimidine base metabolic process" EXACT [] synonym: "upregulation of pyrimidine base metabolic process" EXACT [] xref: GO:0045985 is_a: CCO:P0000627 ! regulation of pyrimidine base metabolic process is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0002662 name: regulation of transcription by carbon catabolites namespace: biological_process def: "Any process involving carbon catabolites that modulates the frequency, rate or extent of transcription." [GOC:go_curators] subset: gosubset_prok xref: GO:0045990 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:P0002663 name: positive regulation of transcription by carbon catabolites namespace: biological_process def: "Any process involving carbon catabolites that activates or increases the rate of transcription." [GOC:go_curators] subset: gosubset_prok synonym: "activation of transcription by carbon catabolites" NARROW [] synonym: "stimulation of transcription by carbon catabolites" NARROW [] synonym: "up regulation of transcription by carbon catabolites" EXACT [] synonym: "up-regulation of transcription by carbon catabolites" EXACT [] synonym: "upregulation of transcription by carbon catabolites" EXACT [] xref: GO:0045991 is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent is_a: CCO:P0002662 ! regulation of transcription by carbon catabolites [Term] id: CCO:P0002664 name: negative regulation of translational initiation by iron namespace: biological_process def: "Any process involving iron that stops, prevents or reduces the rate of translational initiation." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of translational initiation by iron" EXACT [] synonym: "down-regulation of translational initiation by iron" EXACT [] synonym: "downregulation of translational initiation by iron" EXACT [] synonym: "inhibition of translational initiation by iron" NARROW [] xref: GO:0045993 is_a: CCO:P0000662 ! regulation of translational initiation by iron is_a: CCO:P0002630 ! negative regulation of translational initiation relationship: has_participant CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:P0002665 name: positive regulation of translational initiation by iron namespace: biological_process def: "Any process involving iron that activates or increases the rate of translational initiation." [GOC:go_curators] subset: gosubset_prok synonym: "activation of translational initiation by iron" NARROW [] synonym: "stimulation of translational initiation by iron" NARROW [] synonym: "up regulation of translational initiation by iron" EXACT [] synonym: "up-regulation of translational initiation by iron" EXACT [] synonym: "upregulation of translational initiation by iron" EXACT [] xref: GO:0045994 is_a: CCO:P0000662 ! regulation of translational initiation by iron is_a: CCO:P0002631 ! positive regulation of translational initiation relationship: has_participant CCO:B0001474 ! TNFA_HUMAN [Term] id: CCO:P0002666 name: negative regulation of transcription by pheromones namespace: biological_process def: "Any process involving pheromones that stops, prevents or reduces the rate of transcription." [GOC:go_curators] subset: gosubset_prok synonym: "down regulation of transcription by pheromones" EXACT [] synonym: "down-regulation of transcription by pheromones" EXACT [] synonym: "downregulation of transcription by pheromones" EXACT [] synonym: "inhibition of transcription by pheromones" NARROW [] xref: GO:0045996 is_a: CCO:P0000849 ! regulation of transcription by pheromones is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent [Term] id: CCO:P0002667 name: negative regulation of ecdysteroid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids." [GOC:go_curators] synonym: "down regulation of ecdysteroid biosynthetic process" EXACT [] synonym: "down-regulation of ecdysteroid biosynthetic process" EXACT [] synonym: "downregulation of ecdysteroid biosynthetic process" EXACT [] synonym: "inhibition of ecdysteroid biosynthetic process" NARROW [] synonym: "negative regulation of ecdysteroid anabolism" EXACT [] synonym: "negative regulation of ecdysteroid biosynthesis" EXACT [] synonym: "negative regulation of ecdysteroid formation" EXACT [] synonym: "negative regulation of ecdysteroid synthesis" EXACT [] xref: GO:0045997 is_a: CCO:P0000805 ! regulation of ecdysteroid biosynthetic process is_a: CCO:P0001611 ! negative regulation of hormone biosynthetic process is_a: CCO:P0002644 ! negative regulation of ecdysteroid metabolic process [Term] id: CCO:P0002668 name: positive regulation of ecdysteroid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids." [GOC:go_curators] synonym: "activation of ecdysteroid biosynthetic process" NARROW [] synonym: "positive regulation of ecdysteroid anabolism" EXACT [] synonym: "positive regulation of ecdysteroid biosynthesis" EXACT [] synonym: "positive regulation of ecdysteroid formation" EXACT [] synonym: "positive regulation of ecdysteroid synthesis" EXACT [] synonym: "stimulation of ecdysteroid biosynthetic process" NARROW [] synonym: "up regulation of ecdysteroid biosynthetic process" EXACT [] synonym: "up-regulation of ecdysteroid biosynthetic process" EXACT [] synonym: "upregulation of ecdysteroid biosynthetic process" EXACT [] xref: GO:0045998 is_a: CCO:P0000805 ! regulation of ecdysteroid biosynthetic process is_a: CCO:P0002645 ! positive regulation of ecdysteroid metabolic process is_a: CCO:P0002746 ! positive regulation of hormone biosynthetic process [Term] id: CCO:P0002669 name: negative regulation of ecdysteroid secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of ecdysteroid." [GOC:go_curators] synonym: "down regulation of ecdysteroid secretion" EXACT [] synonym: "down-regulation of ecdysteroid secretion" EXACT [] synonym: "downregulation of ecdysteroid secretion" EXACT [] synonym: "inhibition of ecdysteroid secretion" NARROW [] xref: GO:0045999 is_a: CCO:P0000806 ! regulation of ecdysteroid secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0002670 name: positive regulation of ecdysteroid secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid." [GOC:go_curators] synonym: "activation of ecdysteroid secretion" NARROW [] synonym: "stimulation of ecdysteroid secretion" NARROW [] synonym: "up regulation of ecdysteroid secretion" EXACT [] synonym: "up-regulation of ecdysteroid secretion" EXACT [] synonym: "upregulation of ecdysteroid secretion" EXACT [] xref: GO:0046000 is_a: CCO:P0000806 ! regulation of ecdysteroid secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion [Term] id: CCO:P0002671 name: regulation of activated T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of activated T cell proliferation." [GOC:go_curators] synonym: "regulation of activated T lymphocyte proliferation" EXACT [] synonym: "regulation of activated T-cell proliferation" EXACT [] synonym: "regulation of activated T-lymphocyte proliferation" EXACT [] xref: GO:0046006 is_a: CCO:P0002046 ! regulation of T cell proliferation relationship: regulates CCO:P0002957 ! activated T cell proliferation [Term] id: CCO:P0002672 name: negative regulation of activated T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation." [GOC:go_curators] synonym: "down regulation of activated T cell proliferation" EXACT [] synonym: "down-regulation of activated T cell proliferation" EXACT [] synonym: "downregulation of activated T cell proliferation" EXACT [] synonym: "inhibition of activated T cell proliferation" NARROW [] synonym: "negative regulation of activated T lymphocyte proliferation" EXACT [] synonym: "negative regulation of activated T-cell proliferation" EXACT [] synonym: "negative regulation of activated T-lymphocyte proliferation" EXACT [] xref: GO:0046007 is_a: CCO:P0002047 ! negative regulation of T cell proliferation is_a: CCO:P0002671 ! regulation of activated T cell proliferation relationship: has_participant CCO:B0058606 ! FOXP3_HUMAN relationship: negatively_regulates CCO:P0002957 ! activated T cell proliferation [Term] id: CCO:P0002673 name: regulation of oskar mRNA translation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex." [GOC:go_curators, PMID:12538512] xref: GO:0046011 is_a: CCO:P0000660 ! regulation of translation [Term] id: CCO:P0002674 name: positive regulation of oskar mRNA translation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oskar mRNA translation." [GOC:go_curators] synonym: "activation of oskar mRNA translation" NARROW [] synonym: "stimulation of oskar mRNA translation" NARROW [] synonym: "up regulation of oskar mRNA translation" EXACT [] synonym: "up-regulation of oskar mRNA translation" EXACT [] synonym: "upregulation of oskar mRNA translation" EXACT [] xref: GO:0046012 is_a: CCO:P0002524 ! positive regulation of translation is_a: CCO:P0002673 ! regulation of oskar mRNA translation [Term] id: CCO:P0002675 name: regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "regulation of resting T cell proliferation" EXACT [] synonym: "regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "regulation of T-cell homeostatic proliferation" EXACT [] synonym: "regulation of T-lymphocyte homeostatic proliferation" EXACT [] xref: GO:0046013 is_a: CCO:P0002046 ! regulation of T cell proliferation relationship: regulates CCO:P0000470 ! T cell homeostatic proliferation [Term] id: CCO:P0002676 name: negative regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "down regulation of T cell homeostatic proliferation" EXACT [] synonym: "down-regulation of T cell homeostatic proliferation" EXACT [] synonym: "downregulation of T cell homeostatic proliferation" EXACT [] synonym: "inhibition of T cell homeostatic proliferation" NARROW [] synonym: "negative regulation of resting T cell proliferation" EXACT [] synonym: "negative regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "negative regulation of T-cell homeostatic proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte homeostatic proliferation" EXACT [] xref: GO:0046014 is_a: CCO:P0002047 ! negative regulation of T cell proliferation is_a: CCO:P0002675 ! regulation of T cell homeostatic proliferation relationship: negatively_regulates CCO:P0000470 ! T cell homeostatic proliferation [Term] id: CCO:P0002677 name: regulation of transcription by glucose namespace: biological_process def: "Any process involving glucose that modulates the frequency, rate or extent or transcription." [GOC:go_curators] subset: gosubset_prok xref: GO:0046015 is_a: CCO:P0002662 ! regulation of transcription by carbon catabolites [Term] id: CCO:P0002678 name: positive regulation of transcription by glucose namespace: biological_process def: "Any process involving glucose that activates or increases the rate of transcription." [GOC:go_curators] subset: gosubset_prok synonym: "activation of transcription by glucose" NARROW [] synonym: "stimulation of transcription by glucose" NARROW [] synonym: "up regulation of transcription by glucose" EXACT [] synonym: "up-regulation of transcription by glucose" EXACT [] synonym: "upregulation of transcription by glucose" EXACT [] xref: GO:0046016 is_a: CCO:P0002663 ! positive regulation of transcription by carbon catabolites is_a: CCO:P0002677 ! regulation of transcription by glucose [Term] id: CCO:P0002679 name: regulation of transcription from RNA polymerase II promoter by pheromones namespace: biological_process def: "Any process involving pheromones that modulates the frequency, rate or extent or transcription from the RNA polymerase II promoter." [GOC:go_curators] synonym: "regulation of transcription from Pol II promoter by pheromones" EXACT [] xref: GO:0046019 is_a: CCO:P0000849 ! regulation of transcription by pheromones is_a: CCO:P0000979 ! regulation of specific transcription from RNA polymerase II promoter [Term] id: CCO:P0002680 name: negative regulation of transcription from RNA polymerase II promoter by pheromones namespace: biological_process def: "Any process involving pheromones that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter." [GOC:go_curators] synonym: "down regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] synonym: "down-regulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] synonym: "downregulation of transcription from RNA polymerase II promoter by pheromones" EXACT [] synonym: "inhibition of transcription from RNA polymerase II promoter by pheromones" NARROW [] synonym: "negative regulation of transcription from Pol II promoter by pheromones" EXACT [] xref: GO:0046020 is_a: CCO:P0000981 ! negative regulation of specific transcription from RNA polymerase II promoter is_a: CCO:P0002666 ! negative regulation of transcription by pheromones is_a: CCO:P0002679 ! regulation of transcription from RNA polymerase II promoter by pheromones [Term] id: CCO:P0002681 name: positive regulation of vitamin metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] subset: gosubset_prok synonym: "activation of vitamin metabolic process" NARROW [] synonym: "positive regulation of vitamin metabolism" EXACT [] synonym: "stimulation of vitamin metabolic process" NARROW [] synonym: "up regulation of vitamin metabolic process" EXACT [] synonym: "up-regulation of vitamin metabolic process" EXACT [] synonym: "upregulation of vitamin metabolic process" EXACT [] xref: GO:0046136 is_a: CCO:P0001284 ! regulation of vitamin metabolic process is_a: CCO:P0001406 ! positive regulation of cellular metabolic process [Term] id: CCO:P0002682 name: negative regulation of vitamin metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body." [GOC:ai] subset: gosubset_prok synonym: "down regulation of vitamin metabolic process" EXACT [] synonym: "down-regulation of vitamin metabolic process" EXACT [] synonym: "downregulation of vitamin metabolic process" EXACT [] synonym: "inhibition of vitamin metabolic process" NARROW [] synonym: "negative regulation of vitamin metabolism" EXACT [] xref: GO:0046137 is_a: CCO:P0001284 ! regulation of vitamin metabolic process is_a: CCO:P0001405 ! negative regulation of cellular metabolic process [Term] id: CCO:P0002683 name: regulation of glucosylceramide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide." [GOC:ai] subset: gosubset_prok synonym: "regulation of glucosylceramide anabolism" EXACT [] synonym: "regulation of glucosylceramide biosynthesis" EXACT [] synonym: "regulation of glucosylceramide formation" EXACT [] synonym: "regulation of glucosylceramide synthesis" EXACT [] xref: GO:0046317 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0002684 name: negative regulation of glucosylceramide biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide." [GOC:ai] subset: gosubset_prok synonym: "down regulation of glucosylceramide biosynthetic process" EXACT [] synonym: "down-regulation of glucosylceramide biosynthetic process" EXACT [] synonym: "downregulation of glucosylceramide biosynthetic process" EXACT [] synonym: "inhibition of glucosylceramide biosynthetic process" NARROW [] synonym: "negative regulation of glucosylceramide anabolism" EXACT [] synonym: "negative regulation of glucosylceramide biosynthesis" EXACT [] synonym: "negative regulation of glucosylceramide formation" EXACT [] synonym: "negative regulation of glucosylceramide synthesis" EXACT [] xref: GO:0046318 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0002683 ! regulation of glucosylceramide biosynthetic process relationship: has_participant CCO:B0005872 ! AAPK1_HUMAN [Term] id: CCO:P0002685 name: positive regulation of glucosylceramide biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide." [GOC:ai] subset: gosubset_prok synonym: "activation of glucosylceramide biosynthetic process" NARROW [] synonym: "positive regulation of glucosylceramide anabolism" EXACT [] synonym: "positive regulation of glucosylceramide biosynthesis" EXACT [] synonym: "positive regulation of glucosylceramide formation" EXACT [] synonym: "positive regulation of glucosylceramide synthesis" EXACT [] synonym: "stimulation of glucosylceramide biosynthetic process" NARROW [] synonym: "up regulation of glucosylceramide biosynthetic process" EXACT [] synonym: "up-regulation of glucosylceramide biosynthetic process" EXACT [] synonym: "upregulation of glucosylceramide biosynthetic process" EXACT [] xref: GO:0046319 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0002683 ! regulation of glucosylceramide biosynthetic process [Term] id: CCO:P0002686 name: regulation of fatty acid oxidation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fatty acid oxidation." [GOC:ai] subset: gosubset_prok xref: GO:0046320 is_a: CCO:P0001140 ! regulation of fatty acid metabolic process relationship: has_participant CCO:B0016326 ! AAKG2_HUMAN relationship: has_participant CCO:B0054342 ! ACACB_HUMAN relationship: has_participant CCO:B0054517 ! AAKB2_HUMAN relationship: has_participant CCO:B0054520 ! MCAT_HUMAN relationship: has_participant CCO:B0055167 ! CPT2_HUMAN relationship: has_participant CCO:B0055264 ! ACSL1_HUMAN relationship: has_participant CCO:B0055514 ! AAPK2_HUMAN relationship: has_participant CCO:B0058059 ! CPT1B_HUMAN [Term] id: CCO:P0002687 name: positive regulation of fatty acid oxidation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fatty acid oxidation." [GOC:ai] subset: gosubset_prok synonym: "activation of fatty acid oxidation" NARROW [] synonym: "stimulation of fatty acid oxidation" NARROW [] synonym: "up regulation of fatty acid oxidation" EXACT [] synonym: "up-regulation of fatty acid oxidation" EXACT [] synonym: "upregulation of fatty acid oxidation" EXACT [] xref: GO:0046321 is_a: CCO:P0002616 ! positive regulation of fatty acid metabolic process is_a: CCO:P0002686 ! regulation of fatty acid oxidation relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0058555 ! C1QT2_HUMAN [Term] id: CCO:P0002688 name: negative regulation of fatty acid oxidation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid oxidation." [GOC:ai] subset: gosubset_prok synonym: "down regulation of fatty acid oxidation" EXACT [] synonym: "down-regulation of fatty acid oxidation" EXACT [] synonym: "downregulation of fatty acid oxidation" EXACT [] synonym: "inhibition of fatty acid oxidation" NARROW [] xref: GO:0046322 is_a: CCO:P0002615 ! negative regulation of fatty acid metabolic process is_a: CCO:P0002686 ! regulation of fatty acid oxidation [Term] id: CCO:P0002689 name: regulation of JNK cascade namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade." [GOC:bf] synonym: "regulation of SAPK cascade" BROAD [] xref: GO:0046328 is_a: CCO:P0002209 ! regulation of MAPKKK cascade relationship: has_participant CCO:B0001820 ! M3K11_HUMAN relationship: has_participant CCO:B0006034 ! JIP3_HUMAN relationship: has_participant CCO:B0055904 ! JIP2_HUMAN relationship: has_participant CCO:B0059280 ! JIP1_HUMAN relationship: regulates CCO:P0000772 ! JNK cascade [Term] id: CCO:P0002690 name: negative regulation of JNK cascade namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade." [GOC:bf] synonym: "down regulation of JNK cascade" EXACT [] synonym: "down-regulation of JNK cascade" EXACT [] synonym: "downregulation of JNK cascade" EXACT [] synonym: "inhibition of JNK cascade" NARROW [] xref: GO:0046329 is_a: CCO:P0002210 ! negative regulation of MAPKKK cascade is_a: CCO:P0002689 ! regulation of JNK cascade relationship: has_participant CCO:B0019510 ! TAOK3_HUMAN relationship: has_participant CCO:B0035935 ! MEN1_HUMAN relationship: has_participant CCO:B0048588 ! ZN675_HUMAN relationship: has_participant CCO:B0054872 ! AMBP_HUMAN relationship: has_participant CCO:B0058165 ! AIDA_HUMAN relationship: negatively_regulates CCO:P0000772 ! JNK cascade [Term] id: CCO:P0002691 name: positive regulation of JNK cascade namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade." [GOC:bf] synonym: "activation of JNK cascade" NARROW [] synonym: "stimulation of JNK cascade" NARROW [] synonym: "up regulation of JNK cascade" EXACT [] synonym: "up-regulation of JNK cascade" EXACT [] synonym: "upregulation of JNK cascade" EXACT [] xref: GO:0046330 is_a: CCO:P0002211 ! positive regulation of MAPKKK cascade is_a: CCO:P0002689 ! regulation of JNK cascade relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0002130 ! HIPK2_HUMAN relationship: has_participant CCO:B0019510 ! TAOK3_HUMAN relationship: has_participant CCO:B0019513 ! TAOK2_HUMAN relationship: has_participant CCO:B0021316 ! Q9C054_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0055193 ! CD27_HUMAN relationship: has_participant CCO:B0056670 ! Q5VYX9_HUMAN relationship: has_participant CCO:B0056671 ! Q5VYY0_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058679 ! CARD9_HUMAN relationship: has_participant CCO:B0058770 ! TNR27_HUMAN relationship: positively_regulates CCO:P0000772 ! JNK cascade [Term] id: CCO:P0002692 name: regulation of JAK-STAT cascade namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the JAK-STAT signaling pathway." [GOC:bf] xref: GO:0046425 is_a: CCO:P0001017 ! regulation of protein kinase cascade relationship: has_participant CCO:B0002135 ! PIGU_HUMAN relationship: regulates CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0002693 name: negative regulation of JAK-STAT cascade namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the JAK-STAT signaling pathway activity." [GOC:bf] synonym: "down regulation of JAK-STAT cascade" EXACT [] synonym: "down-regulation of JAK-STAT cascade" EXACT [] synonym: "downregulation of JAK-STAT cascade" EXACT [] synonym: "inhibition of JAK-STAT cascade" NARROW [] xref: GO:0046426 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002692 ! regulation of JAK-STAT cascade relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0005280 ! HGS_HUMAN relationship: has_participant CCO:B0005456 ! CAV1_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: negatively_regulates CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0002694 name: positive regulation of JAK-STAT cascade namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity." [GOC:bf] synonym: "activation of JAK-STAT cascade" NARROW [] synonym: "stimulation of JAK-STAT cascade" NARROW [] synonym: "up regulation of JAK-STAT cascade" EXACT [] synonym: "up-regulation of JAK-STAT cascade" EXACT [] synonym: "upregulation of JAK-STAT cascade" EXACT [] xref: GO:0046427 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002692 ! regulation of JAK-STAT cascade relationship: has_participant CCO:B0001557 ! PAR1_HUMAN relationship: has_participant CCO:B0057317 ! IL29_HUMAN relationship: positively_regulates CCO:P0000776 ! JAK-STAT cascade [Term] id: CCO:P0002695 name: regulation of photoreceptor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation." [GOC:go_curators] synonym: "regulation of photoreceptor differentiation" EXACT [] synonym: "regulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] xref: GO:0045673 xref: GO:0046532 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002696 name: negative regulation of photoreceptor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of photoreceptor cell differentiation." [GOC:go_curators] synonym: "down regulation of photoreceptor cell differentiation" EXACT [] synonym: "down regulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] synonym: "down-regulation of photoreceptor cell differentiation" EXACT [] synonym: "down-regulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] synonym: "downregulation of photoreceptor cell differentiation" EXACT [] synonym: "downregulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] synonym: "inhibition of photoreceptor cell differentiation" NARROW [] synonym: "inhibition of photoreceptor differentiation (sensu Endopterygota)" NARROW [] synonym: "negative regulation of photoreceptor differentiation" EXACT [] synonym: "negative regulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] xref: GO:0045674 xref: GO:0046533 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002695 ! regulation of photoreceptor cell differentiation [Term] id: CCO:P0002697 name: positive regulation of photoreceptor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation." [GOC:go_curators] synonym: "activation of photoreceptor cell differentiation" NARROW [] synonym: "activation of photoreceptor differentiation (sensu Endopterygota)" NARROW [] synonym: "positive regulation of photoreceptor differentiation" EXACT [] synonym: "positive regulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] synonym: "stimulation of photoreceptor cell differentiation" NARROW [] synonym: "stimulation of photoreceptor differentiation (sensu Endopterygota)" NARROW [] synonym: "up regulation of photoreceptor cell differentiation" EXACT [] synonym: "up regulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] synonym: "up-regulation of photoreceptor cell differentiation" EXACT [] synonym: "up-regulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] synonym: "upregulation of photoreceptor cell differentiation" EXACT [] synonym: "upregulation of photoreceptor differentiation (sensu Endopterygota)" EXACT [] xref: GO:0045675 xref: GO:0046534 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002695 ! regulation of photoreceptor cell differentiation relationship: has_participant CCO:B0054456 ! CRX_HUMAN [Term] id: CCO:P0002698 name: regulation of Ras protein signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Ras protein signal transduction." [GOC:bf] xref: GO:0046578 is_a: CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN relationship: regulates CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:P0002699 name: positive regulation of Ras protein signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction." [GOC:bf] synonym: "activation of Ras protein signal transduction" NARROW [] synonym: "stimulation of Ras protein signal transduction" NARROW [] synonym: "up regulation of Ras protein signal transduction" EXACT [] synonym: "up-regulation of Ras protein signal transduction" EXACT [] synonym: "upregulation of Ras protein signal transduction" EXACT [] xref: GO:0046579 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction is_a: CCO:P0003019 ! positive regulation of small GTPase mediated signal transduction relationship: has_participant CCO:B0001719 ! NOTC2_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0054855 ! EPO_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: positively_regulates CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:P0002700 name: negative regulation of Ras protein signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Ras protein signal transduction." [GOC:bf] synonym: "down regulation of Ras protein signal transduction" EXACT [] synonym: "down-regulation of Ras protein signal transduction" EXACT [] synonym: "downregulation of Ras protein signal transduction" EXACT [] synonym: "inhibition of Ras protein signal transduction" NARROW [] xref: GO:0046580 is_a: CCO:P0002698 ! regulation of Ras protein signal transduction is_a: CCO:P0003020 ! negative regulation of small GTPase mediated signal transduction relationship: has_participant CCO:B0021718 ! NUP62_HUMAN relationship: has_participant CCO:B0050997 ! MFN2_HUMAN relationship: negatively_regulates CCO:P0000782 ! Ras protein signal transduction [Term] id: CCO:P0002701 name: regulation of calcium-dependent cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction." [GOC:ai] xref: GO:0046586 is_a: CCO:P0001237 ! regulation of cell-cell adhesion [Term] id: CCO:P0002702 name: positive regulation of calcium-dependent cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion." [GOC:ai] synonym: "activation of calcium-dependent cell-cell adhesion" NARROW [] synonym: "stimulation of calcium-dependent cell-cell adhesion" NARROW [] synonym: "up regulation of calcium-dependent cell-cell adhesion" EXACT [] synonym: "up-regulation of calcium-dependent cell-cell adhesion" EXACT [] synonym: "upregulation of calcium-dependent cell-cell adhesion" EXACT [] xref: GO:0046587 is_a: CCO:P0001239 ! positive regulation of cell-cell adhesion is_a: CCO:P0002701 ! regulation of calcium-dependent cell-cell adhesion [Term] id: CCO:P0002703 name: negative regulation of calcium-dependent cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion." [GOC:ai] synonym: "down regulation of calcium-dependent cell-cell adhesion" EXACT [] synonym: "down-regulation of calcium-dependent cell-cell adhesion" EXACT [] synonym: "downregulation of calcium-dependent cell-cell adhesion" EXACT [] synonym: "inhibition of calcium-dependent cell-cell adhesion" NARROW [] xref: GO:0046588 is_a: CCO:P0001238 ! negative regulation of cell-cell adhesion is_a: CCO:P0002701 ! regulation of calcium-dependent cell-cell adhesion relationship: has_participant CCO:B0058192 ! FXYD5_HUMAN [Term] id: CCO:P0002704 name: regulation of insulin receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of insulin receptor signaling." [GOC:bf] synonym: "regulation of insulin receptor signalling pathway" EXACT [] xref: GO:0046626 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0005873 ! SN1L2_HUMAN relationship: regulates CCO:P0000818 ! insulin receptor signaling pathway [Term] id: CCO:P0002705 name: negative regulation of insulin receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling." [GOC:bf] synonym: "down regulation of insulin receptor signaling pathway" EXACT [] synonym: "down-regulation of insulin receptor signaling pathway" EXACT [] synonym: "downregulation of insulin receptor signaling pathway" EXACT [] synonym: "inhibition of insulin receptor signaling pathway" NARROW [] synonym: "negative regulation of insulin receptor signalling pathway" EXACT [] xref: GO:0046627 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002704 ! regulation of insulin receptor signaling pathway relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0006162 ! SOCS3_HUMAN relationship: has_participant CCO:B0054443 ! SOCS1_HUMAN relationship: has_participant CCO:B0054873 ! FETUA_HUMAN relationship: has_participant CCO:B0055145 ! ENPP1_HUMAN relationship: negatively_regulates CCO:P0000818 ! insulin receptor signaling pathway [Term] id: CCO:P0002706 name: positive regulation of insulin receptor signaling pathway namespace: biological_process def: "Any process that increases the frequency, rate or extent of insulin receptor signaling." [GOC:bf] synonym: "activation of insulin receptor signaling pathway" NARROW [] synonym: "positive regulation of insulin receptor signalling pathway" EXACT [] synonym: "stimulation of insulin receptor signaling pathway" NARROW [] synonym: "up regulation of insulin receptor signaling pathway" EXACT [] synonym: "up-regulation of insulin receptor signaling pathway" EXACT [] synonym: "upregulation of insulin receptor signaling pathway" EXACT [] xref: GO:0046628 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002704 ! regulation of insulin receptor signaling pathway relationship: has_participant CCO:B0054852 ! INS_HUMAN relationship: positively_regulates CCO:P0000818 ! insulin receptor signaling pathway [Term] id: CCO:P0002707 name: gamma-delta T cell proliferation namespace: biological_process def: "The expansion of a gamma-delta T cell population by cell division." [GOC:ai] synonym: "gamma-delta T lymphocyte proliferation" EXACT [] synonym: "gamma-delta T-cell proliferation" EXACT [] synonym: "gamma-delta T-lymphocyte proliferation" EXACT [] xref: GO:0046630 is_a: CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0002708 name: alpha-beta T cell proliferation namespace: biological_process def: "The expansion of an alpha-beta T cell population by cell division." [GOC:ai] synonym: "alpha-beta T lymphocyte proliferation" EXACT [] synonym: "alpha-beta T-cell proliferation" EXACT [] synonym: "alpha-beta T-lymphocyte proliferation" EXACT [] xref: GO:0046633 is_a: CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0002709 name: regulation of alpha-beta T cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of alpha-beta T cell activation." [GOC:ai] synonym: "regulation of alpha-beta T lymphocyte activation" EXACT [] synonym: "regulation of alpha-beta T-cell activation" EXACT [] synonym: "regulation of alpha-beta T-lymphocyte activation" EXACT [] xref: GO:0046634 is_a: CCO:P0002981 ! regulation of T cell activation [Term] id: CCO:P0002710 name: positive regulation of alpha-beta T cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation." [GOC:ai] synonym: "activation of alpha-beta T cell activation" NARROW [] synonym: "positive regulation of alpha-beta T lymphocyte activation" EXACT [] synonym: "positive regulation of alpha-beta T-cell activation" EXACT [] synonym: "positive regulation of alpha-beta T-lymphocyte activation" EXACT [] synonym: "stimulation of alpha-beta T cell activation" NARROW [] synonym: "up regulation of alpha-beta T cell activation" EXACT [] synonym: "up-regulation of alpha-beta T cell activation" EXACT [] synonym: "upregulation of alpha-beta T cell activation" EXACT [] xref: GO:0046635 is_a: CCO:P0002709 ! regulation of alpha-beta T cell activation is_a: CCO:P0002988 ! positive regulation of T cell activation [Term] id: CCO:P0002711 name: negative regulation of alpha-beta T cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell activation." [GOC:ai] synonym: "down regulation of alpha-beta T cell activation" EXACT [] synonym: "down-regulation of alpha-beta T cell activation" EXACT [] synonym: "downregulation of alpha-beta T cell activation" EXACT [] synonym: "inhibition of alpha-beta T cell activation" NARROW [] synonym: "negative regulation of alpha-beta T lymphocyte activation" EXACT [] synonym: "negative regulation of alpha-beta T-cell activation" EXACT [] synonym: "negative regulation of alpha-beta T-lymphocyte activation" EXACT [] xref: GO:0046636 is_a: CCO:P0002709 ! regulation of alpha-beta T cell activation is_a: CCO:P0002986 ! negative regulation of T cell activation [Term] id: CCO:P0002712 name: regulation of alpha-beta T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation." [GOC:ai] synonym: "regulation of alpha-beta T lymphocyte differentiation" EXACT [] synonym: "regulation of alpha-beta T-cell differentiation" EXACT [] synonym: "regulation of alpha-beta T-lymphocyte differentiation" EXACT [] xref: GO:0046637 is_a: CCO:P0002394 ! regulation of T cell differentiation is_a: CCO:P0002709 ! regulation of alpha-beta T cell activation [Term] id: CCO:P0002713 name: positive regulation of alpha-beta T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation." [GOC:ai] synonym: "activation of alpha-beta T cell differentiation" NARROW [] synonym: "positive regulation of alpha-beta T lymphocyte differentiation" EXACT [] synonym: "positive regulation of alpha-beta T-cell differentiation" EXACT [] synonym: "positive regulation of alpha-beta T-lymphocyte differentiation" EXACT [] synonym: "stimulation of alpha-beta T cell differentiation" NARROW [] synonym: "up regulation of alpha-beta T cell differentiation" EXACT [] synonym: "up-regulation of alpha-beta T cell differentiation" EXACT [] synonym: "upregulation of alpha-beta T cell differentiation" EXACT [] xref: GO:0046638 is_a: CCO:P0002396 ! positive regulation of T cell differentiation is_a: CCO:P0002710 ! positive regulation of alpha-beta T cell activation is_a: CCO:P0002712 ! regulation of alpha-beta T cell differentiation relationship: has_participant CCO:B0006097 ! PNPH_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:P0002714 name: negative regulation of alpha-beta T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell differentiation." [GOC:ai] synonym: "down regulation of alpha-beta T cell differentiation" EXACT [] synonym: "down-regulation of alpha-beta T cell differentiation" EXACT [] synonym: "downregulation of alpha-beta T cell differentiation" EXACT [] synonym: "inhibition of alpha-beta T cell differentiation" NARROW [] synonym: "negative regulation of alpha-beta T lymphocyte differentiation" EXACT [] synonym: "negative regulation of alpha-beta T-cell differentiation" EXACT [] synonym: "negative regulation of alpha-beta T-lymphocyte differentiation" EXACT [] xref: GO:0046639 is_a: CCO:P0002395 ! negative regulation of T cell differentiation is_a: CCO:P0002711 ! negative regulation of alpha-beta T cell activation is_a: CCO:P0002712 ! regulation of alpha-beta T cell differentiation relationship: has_participant CCO:B0056066 ! SHH_HUMAN [Term] id: CCO:P0002715 name: regulation of alpha-beta T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation." [GOC:ai] synonym: "regulation of alpha-beta T lymphocyte proliferation" EXACT [] synonym: "regulation of alpha-beta T-cell proliferation" EXACT [] synonym: "regulation of alpha-beta T-lymphocyte proliferation" EXACT [] xref: GO:0046640 is_a: CCO:P0002046 ! regulation of T cell proliferation is_a: CCO:P0002709 ! regulation of alpha-beta T cell activation relationship: regulates CCO:P0002708 ! alpha-beta T cell proliferation [Term] id: CCO:P0002716 name: positive regulation of alpha-beta T cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation." [GOC:ai] synonym: "activation of alpha-beta T cell proliferation" NARROW [] synonym: "positive regulation of alpha-beta T lymphocyte proliferation" EXACT [] synonym: "positive regulation of alpha-beta T-cell proliferation" EXACT [] synonym: "positive regulation of alpha-beta T-lymphocyte proliferation" EXACT [] synonym: "stimulation of alpha-beta T cell proliferation" NARROW [] synonym: "up regulation of alpha-beta T cell proliferation" EXACT [] synonym: "up-regulation of alpha-beta T cell proliferation" EXACT [] synonym: "upregulation of alpha-beta T cell proliferation" EXACT [] xref: GO:0046641 is_a: CCO:P0002041 ! positive regulation of T cell proliferation is_a: CCO:P0002710 ! positive regulation of alpha-beta T cell activation is_a: CCO:P0002715 ! regulation of alpha-beta T cell proliferation relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0055972 ! IL27B_HUMAN relationship: positively_regulates CCO:P0002708 ! alpha-beta T cell proliferation [Term] id: CCO:P0002717 name: negative regulation of alpha-beta T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of alpha-beta T cell proliferation." [GOC:ai] synonym: "down regulation of alpha-beta T cell proliferation" EXACT [] synonym: "down-regulation of alpha-beta T cell proliferation" EXACT [] synonym: "downregulation of alpha-beta T cell proliferation" EXACT [] synonym: "inhibition of alpha-beta T cell proliferation" NARROW [] synonym: "negative regulation of alpha-beta T lymphocyte proliferation" EXACT [] synonym: "negative regulation of alpha-beta T-cell proliferation" EXACT [] synonym: "negative regulation of alpha-beta T-lymphocyte proliferation" EXACT [] xref: GO:0046642 is_a: CCO:P0002047 ! negative regulation of T cell proliferation is_a: CCO:P0002711 ! negative regulation of alpha-beta T cell activation is_a: CCO:P0002715 ! regulation of alpha-beta T cell proliferation relationship: negatively_regulates CCO:P0002708 ! alpha-beta T cell proliferation [Term] id: CCO:P0002718 name: regulation of gamma-delta T cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell activation." [GOC:ai] synonym: "regulation of gamma-delta T lymphocyte activation" EXACT [] synonym: "regulation of gamma-delta T-cell activation" EXACT [] synonym: "regulation of gamma-delta T-lymphocyte activation" EXACT [] xref: GO:0046643 is_a: CCO:P0002981 ! regulation of T cell activation [Term] id: CCO:P0002719 name: negative regulation of gamma-delta T cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation." [GOC:ai] synonym: "down regulation of gamma-delta T cell activation" EXACT [] synonym: "down-regulation of gamma-delta T cell activation" EXACT [] synonym: "downregulation of gamma-delta T cell activation" EXACT [] synonym: "inhibition of gamma-delta T cell activation" NARROW [] synonym: "negative regulation of gamma-delta T lymphocyte activation" EXACT [] synonym: "negative regulation of gamma-delta T-cell activation" EXACT [] synonym: "negative regulation of gamma-delta T-lymphocyte activation" EXACT [] xref: GO:0046644 is_a: CCO:P0002718 ! regulation of gamma-delta T cell activation is_a: CCO:P0002986 ! negative regulation of T cell activation [Term] id: CCO:P0002720 name: positive regulation of gamma-delta T cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation." [GOC:ai] synonym: "activation of gamma-delta T cell activation" NARROW [] synonym: "positive regulation of gamma-delta T lymphocyte activation" EXACT [] synonym: "positive regulation of gamma-delta T-cell activation" EXACT [] synonym: "positive regulation of gamma-delta T-lymphocyte activation" EXACT [] synonym: "stimulation of gamma-delta T cell activation" NARROW [] synonym: "up regulation of gamma-delta T cell activation" EXACT [] synonym: "up-regulation of gamma-delta T cell activation" EXACT [] synonym: "upregulation of gamma-delta T cell activation" EXACT [] xref: GO:0046645 is_a: CCO:P0002718 ! regulation of gamma-delta T cell activation is_a: CCO:P0002988 ! positive regulation of T cell activation [Term] id: CCO:P0002721 name: regulation of gamma-delta T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation." [GOC:ai] synonym: "regulation of gamma-delta T lymphocyte proliferation" EXACT [] synonym: "regulation of gamma-delta T-cell proliferation" EXACT [] synonym: "regulation of gamma-delta T-lymphocyte proliferation" EXACT [] xref: GO:0046646 is_a: CCO:P0002046 ! regulation of T cell proliferation is_a: CCO:P0002718 ! regulation of gamma-delta T cell activation relationship: regulates CCO:P0002707 ! gamma-delta T cell proliferation [Term] id: CCO:P0002722 name: negative regulation of gamma-delta T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell proliferation." [GOC:ai] synonym: "down regulation of gamma-delta T cell proliferation" EXACT [] synonym: "down-regulation of gamma-delta T cell proliferation" EXACT [] synonym: "downregulation of gamma-delta T cell proliferation" EXACT [] synonym: "inhibition of gamma-delta T cell proliferation" NARROW [] synonym: "negative regulation of gamma-delta T lymphocyte proliferation" EXACT [] synonym: "negative regulation of gamma-delta T-cell proliferation" EXACT [] synonym: "negative regulation of gamma-delta T-lymphocyte proliferation" EXACT [] xref: GO:0046647 is_a: CCO:P0002047 ! negative regulation of T cell proliferation is_a: CCO:P0002719 ! negative regulation of gamma-delta T cell activation is_a: CCO:P0002721 ! regulation of gamma-delta T cell proliferation relationship: negatively_regulates CCO:P0002707 ! gamma-delta T cell proliferation [Term] id: CCO:P0002723 name: positive regulation of gamma-delta T cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation." [GOC:ai] synonym: "activation of gamma-delta T cell proliferation" NARROW [] synonym: "positive regulation of gamma-delta T lymphocyte proliferation" EXACT [] synonym: "positive regulation of gamma-delta T-cell proliferation" EXACT [] synonym: "positive regulation of gamma-delta T-lymphocyte proliferation" EXACT [] synonym: "stimulation of gamma-delta T cell proliferation" NARROW [] synonym: "up regulation of gamma-delta T cell proliferation" EXACT [] synonym: "up-regulation of gamma-delta T cell proliferation" EXACT [] synonym: "upregulation of gamma-delta T cell proliferation" EXACT [] xref: GO:0046648 is_a: CCO:P0002041 ! positive regulation of T cell proliferation is_a: CCO:P0002720 ! positive regulation of gamma-delta T cell activation is_a: CCO:P0002721 ! regulation of gamma-delta T cell proliferation relationship: positively_regulates CCO:P0002707 ! gamma-delta T cell proliferation [Term] id: CCO:P0002724 name: lymphocyte proliferation namespace: biological_process def: "The expansion of a lymphocyte population by cell division." [GOC:ai] xref: GO:0046651 is_a: CCO:P0001724 ! mononuclear cell proliferation relationship: has_participant CCO:B0002161 ! HELLS_HUMAN relationship: has_participant CCO:B0054998 ! IMDH2_HUMAN [Term] id: CCO:P0002725 name: regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "regulation of retinal programmed cell death" EXACT [GOC:tb] xref: GO:0046668 is_a: CCO:P0002149 ! regulation of programmed cell death relationship: has_participant CCO:B0001502 ! FGF2_HUMAN [Term] id: CCO:P0002726 name: regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "regulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] xref: GO:0046669 is_a: CCO:P0002725 ! regulation of retinal cell programmed cell death [Term] id: CCO:P0002727 name: positive regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "activation of retinal programmed cell death" NARROW [] synonym: "positive regulation of retinal programmed cell death" EXACT [GOC:tb] synonym: "stimulation of retinal programmed cell death" NARROW [] synonym: "up regulation of retinal programmed cell death" EXACT [] synonym: "up-regulation of retinal programmed cell death" EXACT [] synonym: "upregulation of retinal programmed cell death" EXACT [] xref: GO:0046670 is_a: CCO:P0002150 ! positive regulation of programmed cell death is_a: CCO:P0002725 ! regulation of retinal cell programmed cell death [Term] id: CCO:P0002728 name: negative regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "down regulation of retinal programmed cell death" EXACT [] synonym: "down-regulation of retinal programmed cell death" EXACT [] synonym: "downregulation of retinal programmed cell death" EXACT [] synonym: "inhibition of retinal programmed cell death" NARROW [] synonym: "negative regulation of retinal programmed cell death" EXACT [GOC:tb] xref: GO:0046671 is_a: CCO:P0002151 ! negative regulation of programmed cell death is_a: CCO:P0002725 ! regulation of retinal cell programmed cell death relationship: has_participant CCO:B0057586 ! BHLH4_HUMAN [Term] id: CCO:P0002729 name: positive regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "activation of retinal cell programmed cell death (sensu Endopterygota)" NARROW [] synonym: "positive regulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] synonym: "stimulation of retinal cell programmed cell death (sensu Endopterygota)" NARROW [] synonym: "up regulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] synonym: "up-regulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] synonym: "upregulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] xref: GO:0046672 is_a: CCO:P0002726 ! regulation of compound eye retinal cell programmed cell death is_a: CCO:P0002727 ! positive regulation of retinal cell programmed cell death [Term] id: CCO:P0002730 name: negative regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "down regulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] synonym: "down-regulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] synonym: "downregulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] synonym: "inhibition of retinal cell programmed cell death (sensu Endopterygota)" NARROW [] synonym: "negative regulation of retina cell programmed cell death (sensu Endopterygota)" EXACT [] synonym: "negative regulation of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] xref: GO:0046673 is_a: CCO:P0002726 ! regulation of compound eye retinal cell programmed cell death is_a: CCO:P0002728 ! negative regulation of retinal cell programmed cell death [Term] id: CCO:P0002731 name: induction of retinal programmed cell death namespace: biological_process def: "A process which directly activates any of the steps required for programmed cell death in the retina." [GOC:ai] xref: GO:0046674 is_a: CCO:P0001050 ! induction of programmed cell death is_a: CCO:P0002727 ! positive regulation of retinal cell programmed cell death [Term] id: CCO:P0002732 name: induction of compound eye retinal cell programmed cell death namespace: biological_process def: "A process which directly activates any of the steps required for programmed cell death in the compound eye retina." [GOC:ai] synonym: "induction of retinal cell programmed cell death (sensu Endopterygota)" EXACT [] xref: GO:0046675 is_a: CCO:P0002729 ! positive regulation of compound eye retinal cell programmed cell death is_a: CCO:P0002731 ! induction of retinal programmed cell death [Term] id: CCO:P0002733 name: negative regulation of insulin secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of insulin." [GOC:ai] synonym: "down regulation of insulin secretion" EXACT [] synonym: "down-regulation of insulin secretion" EXACT [] synonym: "downregulation of insulin secretion" EXACT [] synonym: "inhibition of insulin secretion" NARROW [] xref: GO:0046676 is_a: CCO:P0002748 ! negative regulation of hormone secretion is_a: CCO:P0002956 ! regulation of insulin secretion relationship: has_participant CCO:B0030971 ! IRK11_HUMAN relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0041239 ! PSMD9_HUMAN relationship: has_participant CCO:B0058169 ! FAM3D_HUMAN [Term] id: CCO:P0002734 name: modification by virus of host mRNA processing namespace: biological_process def: "Any viral process that interferes with the processing of mRNA in the host cell." [ISBN:0781718325] synonym: "viral perturbation of host mRNA processing" EXACT [] xref: GO:0046778 xref: Reactome:168315 xref: Reactome:168859 xref: Reactome:168883 is_a: CCO:P0001138 ! modulation by virus of host transcription [Term] id: CCO:P0002735 name: suppression by virus of expression of host genes with introns namespace: biological_process def: "Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed." [PMID:11598019] synonym: "negative regulation by virus of expression of host genes with introns" EXACT [] synonym: "viral inhibition of expression of host genes with introns" EXACT [] xref: GO:0046779 is_a: CCO:P0001138 ! modulation by virus of host transcription [Term] id: CCO:P0002736 name: suppression by virus of host mRNA splicing namespace: biological_process def: "Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production." [ISBN:0781718325] synonym: "negative regulation by virus of host mRNA splicing" EXACT [] synonym: "viral inhibition of host mRNA splicing" EXACT [] xref: GO:0046780 is_a: CCO:P0002734 ! modification by virus of host mRNA processing [Term] id: CCO:P0002737 name: dispersion by virus of host splicing factors namespace: biological_process def: "Any viral process that disperses host splicing factors (snRNPs) to prevent host mRNA splicing, thus reducing host protein production." [ISBN:0781718325] synonym: "viral dispersion of host splicing factors" EXACT [] xref: GO:0046781 is_a: CCO:P0002734 ! modification by virus of host mRNA processing [Term] id: CCO:P0002738 name: regulation of viral transcription namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the transcription of the viral genome." [GOC:ai] xref: GO:0046782 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent relationship: has_participant CCO:B0058037 ! Q8WY32_HUMAN [Term] id: CCO:P0002739 name: modification by virus of host polysomes namespace: biological_process def: "Any viral process that interferes with and inhibits the assembly and function of polysomes." [PMID:10438802] comment: See also the cellular component term 'polysome ; GO:0005844'. synonym: "viral perturbation of polysomes" EXACT [] xref: GO:0046783 is_a: CCO:P0001139 ! regulation of host mRNA translation by virus [Term] id: CCO:P0002740 name: induction by virus of modification of host RNA polymerase II namespace: biological_process def: "The viral induction of modification to the host RNA polymerase II." [PMID:7637000] synonym: "virus-induced modification of host RNA polymerase II" EXACT [] xref: GO:0046793 is_a: CCO:P0001138 ! modulation by virus of host transcription [Term] id: CCO:P0002741 name: regulation of follicle-stimulating hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone." [GOC:ai] xref: GO:0046880 is_a: CCO:P0001578 ! regulation of gonadotropin secretion [Term] id: CCO:P0002742 name: positive regulation of follicle-stimulating hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone." [GOC:ai] synonym: "activation of follicle-stimulating hormone secretion" NARROW [] synonym: "stimulation of follicle-stimulating hormone secretion" NARROW [] synonym: "up regulation of follicle-stimulating hormone secretion" EXACT [] synonym: "up-regulation of follicle-stimulating hormone secretion" EXACT [] synonym: "upregulation of follicle-stimulating hormone secretion" EXACT [] xref: GO:0046881 is_a: CCO:P0001580 ! positive regulation of gonadotropin secretion is_a: CCO:P0002741 ! regulation of follicle-stimulating hormone secretion relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0039075 ! INHBB_HUMAN [Term] id: CCO:P0002743 name: negative regulation of follicle-stimulating hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone." [GOC:ai] synonym: "down regulation of follicle-stimulating hormone secretion" EXACT [] synonym: "down-regulation of follicle-stimulating hormone secretion" EXACT [] synonym: "downregulation of follicle-stimulating hormone secretion" EXACT [] synonym: "inhibition of follicle-stimulating hormone secretion" NARROW [] xref: GO:0046882 is_a: CCO:P0001579 ! negative regulation of gonadotropin secretion is_a: CCO:P0002741 ! regulation of follicle-stimulating hormone secretion relationship: has_participant CCO:B0001485 ! INHA_HUMAN relationship: has_participant CCO:B0001498 ! INHBA_HUMAN relationship: has_participant CCO:B0039075 ! INHBB_HUMAN relationship: has_participant CCO:B0055111 ! FST_HUMAN [Term] id: CCO:P0002744 name: regulation of hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell or group of cells." [GOC:ai] xref: GO:0046883 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0037954 ! 7B2_HUMAN [Term] id: CCO:P0002745 name: regulation of hormone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." [GOC:ai] synonym: "regulation of hormone anabolism" EXACT [] synonym: "regulation of hormone biosynthesis" EXACT [] synonym: "regulation of hormone formation" EXACT [] synonym: "regulation of hormone synthesis" EXACT [] xref: GO:0046885 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process is_a: CCO:P0001608 ! regulation of hormone metabolic process relationship: has_participant CCO:B0058340 ! TREF1_HUMAN [Term] id: CCO:P0002746 name: positive regulation of hormone biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones." [GOC:ai] synonym: "activation of hormone biosynthetic process" NARROW [] synonym: "positive regulation of hormone anabolism" EXACT [] synonym: "positive regulation of hormone biosynthesis" EXACT [] synonym: "positive regulation of hormone formation" EXACT [] synonym: "positive regulation of hormone synthesis" EXACT [] synonym: "stimulation of hormone biosynthetic process" NARROW [] synonym: "up regulation of hormone biosynthetic process" EXACT [] synonym: "up-regulation of hormone biosynthetic process" EXACT [] synonym: "upregulation of hormone biosynthetic process" EXACT [] xref: GO:0046886 is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0001610 ! positive regulation of hormone metabolic process is_a: CCO:P0002745 ! regulation of hormone biosynthetic process relationship: has_participant CCO:B0005430 ! HIF1A_HUMAN relationship: has_participant CCO:B0005551 ! ARNT_HUMAN [Term] id: CCO:P0002747 name: positive regulation of hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell or group of cells." [GOC:ai] synonym: "activation of hormone secretion" NARROW [] synonym: "stimulation of hormone secretion" NARROW [] synonym: "up regulation of hormone secretion" EXACT [] synonym: "up-regulation of hormone secretion" EXACT [] synonym: "upregulation of hormone secretion" EXACT [] xref: GO:0046887 is_a: CCO:P0002744 ! regulation of hormone secretion is_a: CCO:P0002852 ! positive regulation of cellular process relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0043823 ! EDN3_HUMAN [Term] id: CCO:P0002748 name: negative regulation of hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a hormone from a cell or group of cells." [GOC:ai] synonym: "down regulation of hormone secretion" EXACT [] synonym: "down-regulation of hormone secretion" EXACT [] synonym: "downregulation of hormone secretion" EXACT [] synonym: "inhibition of hormone secretion" NARROW [] xref: GO:0046888 is_a: CCO:P0002744 ! regulation of hormone secretion is_a: CCO:P0002853 ! negative regulation of cellular process relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN relationship: has_participant CCO:B0055126 ! IL11_HUMAN [Term] id: CCO:P0002749 name: regulation of neurotransmitter secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell or group of cells." [GOC:ai] xref: GO:0046928 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0006235 ! SNCAP_HUMAN relationship: has_participant CCO:B0032797 ! ACHB4_HUMAN relationship: has_participant CCO:B0054834 ! NGF_HUMAN relationship: has_participant CCO:B0057214 ! CPLX4_HUMAN relationship: has_participant CCO:B0057273 ! KCMB4_HUMAN relationship: has_participant CCO:B0057992 ! CPLX3_HUMAN [Term] id: CCO:P0002750 name: negative regulation of neurotransmitter secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:ai] synonym: "conotoxin activity" NARROW [] synonym: "down regulation of neurotransmitter secretion" EXACT [] synonym: "down-regulation of neurotransmitter secretion" EXACT [] synonym: "downregulation of neurotransmitter secretion" EXACT [] synonym: "inhibition of neurotransmitter secretion" NARROW [] xref: GO:0046929 is_a: CCO:P0002749 ! regulation of neurotransmitter secretion is_a: CCO:P0002853 ! negative regulation of cellular process [Term] id: CCO:P0002751 name: regulation of hemoglobin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:ai] synonym: "regulation of haemoglobin biosynthesis" EXACT [] synonym: "regulation of haemoglobin biosynthetic process" EXACT [] synonym: "regulation of hemoglobin anabolism" EXACT [] synonym: "regulation of hemoglobin biosynthesis" EXACT [] synonym: "regulation of hemoglobin formation" EXACT [] synonym: "regulation of hemoglobin synthesis" EXACT [] xref: GO:0046984 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0002752 name: positive regulation of hemoglobin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:ai] synonym: "activation of hemoglobin biosynthetic process" NARROW [] synonym: "positive regulation of haemoglobin biosynthesis" EXACT [] synonym: "positive regulation of haemoglobin biosynthetic process" EXACT [] synonym: "positive regulation of hemoglobin anabolism" EXACT [] synonym: "positive regulation of hemoglobin biosynthesis" EXACT [] synonym: "positive regulation of hemoglobin formation" EXACT [] synonym: "positive regulation of hemoglobin synthesis" EXACT [] synonym: "stimulation of hemoglobin biosynthetic process" NARROW [] synonym: "up regulation of hemoglobin biosynthetic process" EXACT [] synonym: "up-regulation of hemoglobin biosynthetic process" EXACT [] synonym: "upregulation of hemoglobin biosynthetic process" EXACT [] xref: GO:0046985 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0002751 ! regulation of hemoglobin biosynthetic process [Term] id: CCO:P0002753 name: negative regulation of hemoglobin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin." [GOC:ai] synonym: "down regulation of hemoglobin biosynthetic process" EXACT [] synonym: "down-regulation of hemoglobin biosynthetic process" EXACT [] synonym: "downregulation of hemoglobin biosynthetic process" EXACT [] synonym: "inhibition of hemoglobin biosynthetic process" NARROW [] synonym: "negative regulation of haemoglobin biosynthesis" EXACT [] synonym: "negative regulation of haemoglobin biosynthetic process" EXACT [] synonym: "negative regulation of hemoglobin anabolism" EXACT [] synonym: "negative regulation of hemoglobin biosynthesis" EXACT [] synonym: "negative regulation of hemoglobin formation" EXACT [] synonym: "negative regulation of hemoglobin synthesis" EXACT [] xref: GO:0046986 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0002751 ! regulation of hemoglobin biosynthetic process relationship: has_participant CCO:B0005674 ! E2AK1_HUMAN [Term] id: CCO:P0002754 name: platelet-derived growth factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands." [GOC:ceb] synonym: "PDGF receptor signaling pathway" EXACT [] synonym: "PDGF receptor signalling pathway" EXACT [] synonym: "PDGFR signaling pathway" EXACT [] xref: GO:0048008 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0001525 ! VEGFA_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0020505 ! PGFRA_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN [Term] id: CCO:P0002755 name: insulin-like growth factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands." [GOC:ceb] synonym: "IGF receptor signaling pathway" EXACT [] synonym: "IGF receptor signalling pathway" EXACT [] xref: GO:0048009 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0005512 ! AKT1_HUMAN relationship: has_participant CCO:B0026608 ! P85A_HUMAN relationship: has_participant CCO:B0051810 ! IRS1_HUMAN relationship: has_participant CCO:B0054633 ! PERQ1_HUMAN [Term] id: CCO:P0002756 name: vascular endothelial growth factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands." [GOC:ceb] synonym: "VEGF receptor signaling pathway" EXACT [] synonym: "VEGF receptor signalling pathway" EXACT [] xref: GO:0048010 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0001402 ! VEGFD_HUMAN relationship: has_participant CCO:B0001635 ! VEGFC_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0001767 ! BMPR2_HUMAN relationship: has_participant CCO:B0005719 ! VGFR1_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0055304 ! VGFR3_HUMAN [Term] id: CCO:P0002757 name: nerve growth factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands." [GOC:ceb] synonym: "nerve growth factor receptor signalling pathway" EXACT [] synonym: "NGF receptor signaling pathway" EXACT [] synonym: "NGF receptor signalling pathway" EXACT [] xref: GO:0048011 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0002075 ! NECD_HUMAN relationship: has_participant CCO:B0005636 ! RAF1_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0058421 ! SORT_HUMAN relationship: has_participant CCO:B0059334 ! UTP11_HUMAN [Term] id: CCO:P0002758 name: hepatocyte growth factor receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands." [GOC:ceb] synonym: "HGF receptor signaling pathway" EXACT [] synonym: "HGF receptor signalling pathway" EXACT [] synonym: "Met signaling pathway" NARROW [] xref: GO:0048012 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0005438 ! MET_HUMAN [Term] id: CCO:P0002759 name: ephrin receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin." [GOC:ceb] synonym: "Eph receptor signaling pathway" EXACT [] synonym: "Eph receptor signalling pathway" EXACT [] xref: GO:0048013 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway relationship: has_participant CCO:B0005832 ! EPHA2_HUMAN relationship: has_participant CCO:B0056107 ! EFNB3_HUMAN [Term] id: CCO:P0002760 name: Tie receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a Tie receptor binding to one of its physiological ligands (angiopoietins)." [GOC:ceb] synonym: "Tek receptor signaling" EXACT [] synonym: "Tie receptor signalling pathway" EXACT [] xref: GO:0048014 is_a: CCO:P0000712 ! transmembrane receptor protein tyrosine kinase signaling pathway [Term] id: CCO:P0002761 name: phosphoinositide-mediated signaling namespace: biological_process def: "A series of molecular signals in which a cell uses a phosphoinositide to convert an extracellular signal into a response." [GOC:ceb, PMID:11331907] subset: gosubset_prok synonym: "inositol phospholipid-mediated signaling" BROAD [] synonym: "phosphoinositide-mediated signalling" EXACT [] xref: GO:0048015 is_a: CCO:P0001148 ! second-messenger-mediated signaling relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001363 ! STK6_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001497 ! IGF1R_HUMAN relationship: has_participant CCO:B0001513 ! PCNA_HUMAN relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0001610 ! PK3CB_HUMAN relationship: has_participant CCO:B0002058 ! SPAG5_HUMAN relationship: has_participant CCO:B0005326 ! PK3CG_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005700 ! H4_HUMAN relationship: has_participant CCO:B0005711 ! P3C2B_HUMAN relationship: has_participant CCO:B0005803 ! TOP2A_HUMAN relationship: has_participant CCO:B0006071 ! P3C2A_HUMAN relationship: has_participant CCO:B0017957 ! RFC4_HUMAN relationship: has_participant CCO:B0018345 ! O00334_HUMAN relationship: has_participant CCO:B0018350 ! PK3CA_HUMAN relationship: has_participant CCO:B0018352 ! PK3CD_HUMAN relationship: has_participant CCO:B0039756 ! FEN1_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0050294 ! HMGB2_HUMAN relationship: has_participant CCO:B0053773 ! PI4P2_HUMAN relationship: has_participant CCO:B0053928 ! A6PVV8_HUMAN relationship: has_participant CCO:B0054130 ! A8MYT4_HUMAN relationship: has_participant CCO:B0054663 ! P3C2G_HUMAN relationship: has_participant CCO:B0054893 ! TYSY_HUMAN relationship: has_participant CCO:B0055181 ! PTAFR_HUMAN relationship: has_participant CCO:B0055278 ! CAH8_HUMAN relationship: has_participant CCO:B0055350 ! PI4KA_HUMAN relationship: has_participant CCO:B0056662 ! Q5VWB9_HUMAN relationship: has_participant CCO:B0056708 ! Q68E11_HUMAN relationship: has_participant CCO:B0057043 ! Q6ZRZ2_HUMAN relationship: has_participant CCO:B0057521 ! PI4P1_HUMAN relationship: has_participant CCO:B0057589 ! PK3C3_HUMAN relationship: has_participant CCO:B0059072 ! PI4KB_HUMAN [Term] id: CCO:P0002762 name: inositol phosphate-mediated signaling namespace: biological_process def: "A series of molecular signals in which a cell uses a water-soluble inositol phosphate to convert an extracellular signal into a response." [GOC:ceb] synonym: "inositol phosphate-mediated signalling" EXACT [] synonym: "inositol phospholipid-mediated signaling" BROAD [] xref: GO:0048016 is_a: CCO:P0002761 ! phosphoinositide-mediated signaling relationship: has_participant CCO:B0058632 ! NMUR2_HUMAN relationship: has_participant CCO:B0058780 ! NMUR1_HUMAN relationship: has_participant CCO:B0059048 ! PLCE1_HUMAN [Term] id: CCO:P0002763 name: inositol lipid-mediated signaling namespace: biological_process def: "A series of molecular signals in which a cell uses an inositol lipid to convert an extracellular signal into a response." [GOC:ceb, PMID:11331907] synonym: "inositol lipid-mediated signalling" EXACT [] synonym: "inositol phospholipid-mediated signaling" BROAD [] xref: GO:0048017 is_a: CCO:P0002761 ! phosphoinositide-mediated signaling [Term] id: CCO:P0002764 name: regulation of melanin biosynthetic process namespace: biological_process def: "Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin." [GOC:jic] subset: gosubset_prok synonym: "regulation of melanin anabolism" EXACT [] synonym: "regulation of melanin biosynthesis" EXACT [] synonym: "regulation of melanin formation" EXACT [] synonym: "regulation of melanin synthesis" EXACT [] xref: GO:0048021 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process [Term] id: CCO:P0002765 name: negative regulation of melanin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin." [GOC:jic] subset: gosubset_prok synonym: "down regulation of melanin biosynthetic process" EXACT [] synonym: "down-regulation of melanin biosynthetic process" EXACT [] synonym: "downregulation of melanin biosynthetic process" EXACT [] synonym: "inhibition of melanin biosynthetic process" NARROW [] synonym: "negative regulation of melanin anabolism" EXACT [] synonym: "negative regulation of melanin biosynthesis" EXACT [] synonym: "negative regulation of melanin formation" EXACT [] synonym: "negative regulation of melanin synthesis" EXACT [] xref: GO:0048022 is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0002764 ! regulation of melanin biosynthetic process [Term] id: CCO:P0002766 name: positive regulation of melanin biosynthetic process namespace: biological_process def: "Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin." [GOC:jic] subset: gosubset_prok synonym: "activation of melanin biosynthetic process" NARROW [] synonym: "positive regulation of melanin anabolism" EXACT [] synonym: "positive regulation of melanin biosynthesis" EXACT [] synonym: "positive regulation of melanin formation" EXACT [] synonym: "positive regulation of melanin synthesis" EXACT [] synonym: "stimulation of melanin biosynthetic process" NARROW [] synonym: "up regulation of melanin biosynthetic process" EXACT [] synonym: "up-regulation of melanin biosynthetic process" EXACT [] synonym: "upregulation of melanin biosynthetic process" EXACT [] xref: GO:0048023 is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0002764 ! regulation of melanin biosynthetic process [Term] id: CCO:P0002767 name: regulation of nuclear mRNA splicing, via spliceosome namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism." [GOC:jic] synonym: "regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "regulation of pre-mRNA splicing" BROAD [] xref: GO:0035055 xref: GO:0048024 is_a: CCO:P0002221 ! regulation of RNA splicing is_a: CCO:P0002925 ! regulation of mRNA processing relationship: has_participant CCO:B0058807 ! NCM_HUMAN [Term] id: CCO:P0002768 name: negative regulation of nuclear mRNA splicing, via spliceosome namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism." [GOC:jic] synonym: "down regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "down regulation of nuclear mRNA splicing, via spliceosome" EXACT [] synonym: "down-regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "down-regulation of nuclear mRNA splicing, via spliceosome" EXACT [] synonym: "downregulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "downregulation of nuclear mRNA splicing, via spliceosome" EXACT [] synonym: "inhibition of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "inhibition of nuclear mRNA splicing, via spliceosome" NARROW [] synonym: "negative regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "negative regulation of pre-mRNA splicing" BROAD [] xref: GO:0035056 xref: GO:0048025 is_a: CCO:P0001781 ! negative regulation of RNA splicing is_a: CCO:P0002767 ! regulation of nuclear mRNA splicing, via spliceosome is_a: CCO:P0002927 ! negative regulation of mRNA processing relationship: has_participant CCO:B0030784 ! FUSIP_HUMAN [Term] id: CCO:P0002769 name: positive regulation of nuclear mRNA splicing, via spliceosome namespace: biological_process def: "Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism." [GOC:jic] synonym: "activation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "activation of nuclear mRNA splicing, via spliceosome" NARROW [] synonym: "positive regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "positive regulation of pre-mRNA splicing" BROAD [] synonym: "stimulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "stimulation of nuclear mRNA splicing, via spliceosome" NARROW [] synonym: "up regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "up regulation of nuclear mRNA splicing, via spliceosome" EXACT [] synonym: "up-regulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "up-regulation of nuclear mRNA splicing, via spliceosome" EXACT [] synonym: "upregulation of nuclear mRNA splicing via U2-type spliceosome" NARROW [] synonym: "upregulation of nuclear mRNA splicing, via spliceosome" EXACT [] xref: GO:0035057 xref: GO:0048026 is_a: CCO:P0001782 ! positive regulation of RNA splicing is_a: CCO:P0002767 ! regulation of nuclear mRNA splicing, via spliceosome is_a: CCO:P0002926 ! positive regulation of mRNA processing [Term] id: CCO:P0002770 name: chromatin-mediated maintenance of transcription namespace: biological_process def: "Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable." [GOC:jic] comment: Note that this process is the opposite of chromatin silencing. This regulation is exemplified by members of the trithorax group, which maintain the active state of homeotic gene transcription. xref: GO:0048096 is_a: CCO:P0002563 ! positive regulation of gene expression, epigenetic is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent relationship: has_participant CCO:B0005415 ! SMRD1_HUMAN relationship: has_participant CCO:B0006007 ! ARI1A_HUMAN relationship: has_participant CCO:B0043865 ! MLL4_HUMAN relationship: has_participant CCO:B0057599 ! ARI1B_HUMAN [Term] id: CCO:P0002771 name: long-term maintenance of gene activation namespace: biological_process def: "Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term." [GOC:jic] comment: Note that this process is the opposite of gene silencing. xref: GO:0048097 is_a: CCO:P0002563 ! positive regulation of gene expression, epigenetic [Term] id: CCO:P0002772 name: somatic stem cell division namespace: biological_process def: "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." [GOC:jic, ISBN:0582227089] synonym: "somatic stem cell renewal" EXACT [] xref: GO:0048103 is_a: CCO:P0001134 ! stem cell division relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001966 ! CD2A2_HUMAN relationship: has_participant CCO:B0036797 ! HXB4_HUMAN relationship: has_participant CCO:B0055549 ! WNT3A_HUMAN [Term] id: CCO:P0002773 name: female germ-line stem cell division namespace: biological_process def: "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." [GOC:jic, GOC:mtg_sensu] synonym: "female germ-line stem cell division (sensu Insecta)" EXACT [] synonym: "female germ-line stem cell renewal" EXACT [] synonym: "female germ-line stem cell renewal (sensu Insecta)" RELATED [] xref: GO:0048132 xref: GO:0048141 is_a: CCO:P0002038 ! germ-line stem cell division [Term] id: CCO:P0002774 name: male germ-line stem cell division namespace: biological_process def: "The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes." [GOC:jic] synonym: "male germ-line stem cell renewal" EXACT [] xref: GO:0048133 is_a: CCO:P0002038 ! germ-line stem cell division [Term] id: CCO:P0002775 name: germ-line cyst formation namespace: biological_process def: "Formation of a cluster of germ-line cells derived from a single founder cell." [GOC:jic, PMID:10370240] xref: GO:0048134 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0002776 name: female germ-line cyst formation namespace: biological_process def: "Formation of a cluster of germ-line cells, in the female gonad, derived from a single founder cell." [GOC:jic] xref: GO:0048135 is_a: CCO:P0002775 ! germ-line cyst formation [Term] id: CCO:P0002777 name: male germ-line cyst formation namespace: biological_process def: "Formation of a cluster of germ-line cells, in the male gonad of an insect, derived from a single founder cell (cystoblast)." [GOC:jic] xref: GO:0048136 is_a: CCO:P0002775 ! germ-line cyst formation [Term] id: CCO:P0002778 name: spermatocyte division namespace: biological_process def: "The meiotic divisions undergone by the primary and secondary spermatocytes to produce a cyst of haploid spermatids." [GOC:jic, ISBN:0879694238] synonym: "spermatocyte cell division" EXACT [] xref: GO:0048137 is_a: CCO:P0003077 ! cell division relationship: part_of CCO:P0002777 ! male germ-line cyst formation [Term] id: CCO:P0002779 name: germarium-derived cystoblast division namespace: biological_process def: "The four rounds of incomplete mitosis undergone by a cystoblast derived from the germarium to form a 16-cell cyst. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells." [GOC:jic, GOC:mtg_sensu, PMID:11131529] synonym: "cystoblast cell division (sensu Insecta)" EXACT [] synonym: "cystoblast division (sensu Insecta)" EXACT [] xref: GO:0048142 is_a: CCO:P0000784 ! cystoblast division relationship: part_of CCO:P0001291 ! germarium-derived female germ-line cyst formation [Term] id: CCO:P0002780 name: fibroblast proliferation namespace: biological_process def: "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." [GOC:jic] xref: GO:0048144 is_a: CCO:P0000815 ! cell proliferation [Term] id: CCO:P0002781 name: regulation of fibroblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jic] xref: GO:0048145 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0002780 ! fibroblast proliferation [Term] id: CCO:P0002782 name: positive regulation of fibroblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jic] synonym: "activation of fibroblast proliferation" NARROW [] synonym: "stimulation of fibroblast proliferation" NARROW [] synonym: "up regulation of fibroblast proliferation" EXACT [] synonym: "up-regulation of fibroblast proliferation" EXACT [] synonym: "upregulation of fibroblast proliferation" EXACT [] xref: GO:0048146 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0002781 ! regulation of fibroblast proliferation relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001469 ! PDGFB_HUMAN relationship: has_participant CCO:B0001480 ! PDGFA_HUMAN relationship: has_participant CCO:B0001494 ! S10A6_HUMAN relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001599 ! CDN1A_HUMAN relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0002176 ! SPHK1_HUMAN relationship: has_participant CCO:B0020505 ! PGFRA_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0054454 ! NDUS4_HUMAN relationship: has_participant CCO:B0054883 ! PA21B_HUMAN relationship: has_participant CCO:B0055279 ! BMI1_HUMAN relationship: has_participant CCO:B0055422 ! FNTB_HUMAN relationship: positively_regulates CCO:P0002780 ! fibroblast proliferation [Term] id: CCO:P0002783 name: negative regulation of fibroblast proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jic] synonym: "down regulation of fibroblast proliferation" EXACT [] synonym: "down-regulation of fibroblast proliferation" EXACT [] synonym: "downregulation of fibroblast proliferation" EXACT [] synonym: "inhibition of fibroblast proliferation" NARROW [] xref: GO:0048147 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0002781 ! regulation of fibroblast proliferation relationship: has_participant CCO:B0055963 ! MORC3_HUMAN relationship: has_participant CCO:B0059087 ! B4GT7_HUMAN relationship: negatively_regulates CCO:P0002780 ! fibroblast proliferation [Term] id: CCO:P0002784 name: regulation of synaptic plasticity namespace: biological_process def: "A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:dph, GOC:jic, GOC:tb, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. xref: GO:0048167 is_a: CCO:P0002958 ! regulation of synaptic transmission relationship: has_participant CCO:B0005489 ! 1433G_HUMAN relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0033427 ! NMDE1_HUMAN relationship: has_participant CCO:B0055270 ! NTF4_HUMAN relationship: has_participant CCO:B0057365 ! CNTN4_HUMAN [Term] id: CCO:P0002785 name: regulation of neuronal synaptic plasticity namespace: biological_process def: "A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers." [GOC:jic, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. xref: GO:0048168 is_a: CCO:P0002784 ! regulation of synaptic plasticity relationship: has_participant CCO:B0005888 ! BHLH2_HUMAN relationship: has_participant CCO:B0006070 ! EGR2_HUMAN relationship: has_participant CCO:B0006302 ! DREB_HUMAN relationship: has_participant CCO:B0054862 ! APOE_HUMAN [Term] id: CCO:P0002786 name: regulation of long-term neuronal synaptic plasticity namespace: biological_process def: "A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers." [GOC:jic, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. xref: GO:0048169 is_a: CCO:P0002785 ! regulation of neuronal synaptic plasticity relationship: has_participant CCO:B0001466 ! RASN_HUMAN relationship: has_participant CCO:B0001468 ! RASK_HUMAN relationship: has_participant CCO:B0018239 ! SYUA_HUMAN [Term] id: CCO:P0002787 name: positive regulation of long-term neuronal synaptic plasticity namespace: biological_process def: "A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers." [GOC:jic, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. synonym: "activation of long-term neuronal synaptic plasticity" NARROW [] synonym: "stimulation of long-term neuronal synaptic plasticity" NARROW [] synonym: "up regulation of long-term neuronal synaptic plasticity" EXACT [] synonym: "up-regulation of long-term neuronal synaptic plasticity" EXACT [] synonym: "upregulation of long-term neuronal synaptic plasticity" EXACT [] xref: GO:0048170 is_a: CCO:P0002786 ! regulation of long-term neuronal synaptic plasticity is_a: CCO:P0002947 ! positive regulation of neurogenesis relationship: has_participant CCO:B0023179 ! NPTN_HUMAN [Term] id: CCO:P0002788 name: negative regulation of long-term neuronal synaptic plasticity namespace: biological_process def: "A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers." [GOC:jic, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. synonym: "down regulation of long-term neuronal synaptic plasticity" EXACT [] synonym: "down-regulation of long-term neuronal synaptic plasticity" EXACT [] synonym: "downregulation of long-term neuronal synaptic plasticity" EXACT [] synonym: "inhibition of long-term neuronal synaptic plasticity" NARROW [] xref: GO:0048171 is_a: CCO:P0002786 ! regulation of long-term neuronal synaptic plasticity is_a: CCO:P0002946 ! negative regulation of neurogenesis [Term] id: CCO:P0002789 name: regulation of short-term neuronal synaptic plasticity namespace: biological_process def: "A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity." [GOC:jic, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. xref: GO:0048172 is_a: CCO:P0002785 ! regulation of neuronal synaptic plasticity relationship: has_participant CCO:B0020611 ! GRIK2_HUMAN [Term] id: CCO:P0002790 name: positive regulation of short-term neuronal synaptic plasticity namespace: biological_process def: "A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity." [GOC:jic, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. synonym: "activation of short-term neuronal synaptic plasticity" NARROW [] synonym: "stimulation of short-term neuronal synaptic plasticity" NARROW [] synonym: "up regulation of short-term neuronal synaptic plasticity" EXACT [] synonym: "up-regulation of short-term neuronal synaptic plasticity" EXACT [] synonym: "upregulation of short-term neuronal synaptic plasticity" EXACT [] xref: GO:0048173 is_a: CCO:P0002789 ! regulation of short-term neuronal synaptic plasticity is_a: CCO:P0002947 ! positive regulation of neurogenesis [Term] id: CCO:P0002791 name: negative regulation of short-term neuronal synaptic plasticity namespace: biological_process def: "A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity." [GOC:jic, http://www.mercksource.com, PMID:11891290] comment: Note that the syntax of the definition of the this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process. synonym: "down regulation of short-term neuronal synaptic plasticity" EXACT [] synonym: "down-regulation of short-term neuronal synaptic plasticity" EXACT [] synonym: "downregulation of short-term neuronal synaptic plasticity" EXACT [] synonym: "inhibition of short-term neuronal synaptic plasticity" NARROW [] xref: GO:0048174 is_a: CCO:P0002789 ! regulation of short-term neuronal synaptic plasticity is_a: CCO:P0002946 ! negative regulation of neurogenesis [Term] id: CCO:P0002792 name: regulation of hepatocyte growth factor biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor." [GOC:jic, http://cancerweb.ncl.ac.uk] synonym: "regulation of hepatocyte growth factor anabolism" EXACT [] synonym: "regulation of hepatocyte growth factor biosynthesis" EXACT [] synonym: "regulation of hepatocyte growth factor formation" EXACT [] synonym: "regulation of hepatocyte growth factor synthesis" EXACT [] synonym: "regulation of HGF biosynthesis" EXACT [] synonym: "regulation of HGF biosynthetic process" EXACT [] synonym: "regulation of scatter factor biosynthesis" EXACT [] synonym: "regulation of scatter factor biosynthetic process" EXACT [] xref: GO:0048176 is_a: CCO:P0002030 ! regulation of cytokine biosynthetic process [Term] id: CCO:P0002793 name: positive regulation of hepatocyte growth factor biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor." [GOC:jic, http://cancerweb.ncl.ac.uk] synonym: "activation of hepatocyte growth factor biosynthetic process" NARROW [] synonym: "positive regulation of hepatocyte growth factor anabolism" EXACT [] synonym: "positive regulation of hepatocyte growth factor biosynthesis" EXACT [] synonym: "positive regulation of hepatocyte growth factor formation" EXACT [] synonym: "positive regulation of hepatocyte growth factor synthesis" EXACT [] synonym: "positive regulation of HGF biosynthesis" EXACT [] synonym: "positive regulation of HGF biosynthetic process" EXACT [] synonym: "positive regulation of scatter factor biosynthesis" EXACT [] synonym: "positive regulation of scatter factor biosynthetic process" EXACT [] synonym: "stimulation of hepatocyte growth factor biosynthetic process" NARROW [] synonym: "up regulation of hepatocyte growth factor biosynthetic process" EXACT [] synonym: "up-regulation of hepatocyte growth factor biosynthetic process" EXACT [] synonym: "upregulation of hepatocyte growth factor biosynthetic process" EXACT [] xref: GO:0048177 is_a: CCO:P0002044 ! positive regulation of cytokine biosynthetic process is_a: CCO:P0002792 ! regulation of hepatocyte growth factor biosynthetic process [Term] id: CCO:P0002794 name: negative regulation of hepatocyte growth factor biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor." [GOC:jic, http://cancerweb.ncl.ac.uk] synonym: "down regulation of hepatocyte growth factor biosynthetic process" EXACT [] synonym: "down-regulation of hepatocyte growth factor biosynthetic process" EXACT [] synonym: "downregulation of hepatocyte growth factor biosynthetic process" EXACT [] synonym: "inhibition of hepatocyte growth factor biosynthetic process" NARROW [] synonym: "negative regulation of hepatocyte growth factor anabolism" EXACT [] synonym: "negative regulation of hepatocyte growth factor biosynthesis" EXACT [] synonym: "negative regulation of hepatocyte growth factor formation" EXACT [] synonym: "negative regulation of hepatocyte growth factor synthesis" EXACT [] synonym: "negative regulation of HGF biosynthesis" EXACT [] synonym: "negative regulation of HGF biosynthetic process" EXACT [] synonym: "negative regulation of scatter factor biosynthesis" EXACT [] synonym: "negative regulation of scatter factor biosynthetic process" EXACT [] xref: GO:0048178 is_a: CCO:P0002031 ! negative regulation of cytokine biosynthetic process is_a: CCO:P0002792 ! regulation of hepatocyte growth factor biosynthetic process relationship: has_participant CCO:B0039075 ! INHBB_HUMAN [Term] id: CCO:P0002795 name: regulation of vesicle targeting, to, from or within Golgi namespace: biological_process def: "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." [GOC:jic, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "regulation of Golgi vesicle targeting" EXACT [] xref: GO:0048209 is_a: CCO:P0001703 ! regulation of microtubule-based process [Term] id: CCO:P0002796 name: regulation of Golgi vesicle fusion to target membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane." [GOC:jic, ISBN:0716731363, PMID:10219233] comment: Note that GTP-binding Rab proteins serve as regulators of vesicle targeting and fusion. xref: GO:0048214 is_a: CCO:P0001418 ! regulation of vesicle fusion [Term] id: CCO:P0002797 name: positive regulation of Golgi vesicle fusion to target membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane." [GOC:jic, ISBN:0716731363, PMID:10219233] synonym: "activation of Golgi vesicle fusion to target membrane" NARROW [] synonym: "stimulation of Golgi vesicle fusion to target membrane" NARROW [] synonym: "up regulation of Golgi vesicle fusion to target membrane" EXACT [] synonym: "up-regulation of Golgi vesicle fusion to target membrane" EXACT [] synonym: "upregulation of Golgi vesicle fusion to target membrane" EXACT [] xref: GO:0048215 is_a: CCO:P0001420 ! positive regulation of vesicle fusion is_a: CCO:P0002796 ! regulation of Golgi vesicle fusion to target membrane [Term] id: CCO:P0002798 name: negative regulation of Golgi vesicle fusion to target membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane." [GOC:jic, ISBN:0716731363, PMID:10219233] synonym: "down regulation of Golgi vesicle fusion to target membrane" EXACT [] synonym: "down-regulation of Golgi vesicle fusion to target membrane" EXACT [] synonym: "downregulation of Golgi vesicle fusion to target membrane" EXACT [] synonym: "inhibition of Golgi vesicle fusion to target membrane" NARROW [] xref: GO:0048216 is_a: CCO:P0001419 ! negative regulation of vesicle fusion is_a: CCO:P0002796 ! regulation of Golgi vesicle fusion to target membrane [Term] id: CCO:P0002799 name: negative regulation of DNA recombination at telomere namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of genetic recombination within the telomere." [GOC:jic, PMID:9635193] synonym: "down regulation of telomeric recombination at telomere" EXACT [] synonym: "down-regulation of telomeric recombination at telomere" EXACT [] synonym: "downregulation of telomeric recombination at telomere" EXACT [] synonym: "inhibition of telomeric recombination at telomere" NARROW [] synonym: "negative regulation of telomeric recombination at telomere" EXACT [GOC:tb] synonym: "suppression of telomeric recombination at telomere" EXACT [] xref: GO:0048239 is_a: CCO:P0002607 ! negative regulation of DNA recombination [Term] id: CCO:P0002800 name: mRNA stabilization namespace: biological_process def: "Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules." [GOC:jic] subset: gosubset_prok xref: GO:0048255 is_a: CCO:P0002223 ! regulation of mRNA stability is_a: CCO:P0002224 ! RNA stabilization relationship: has_participant CCO:B0005854 ! PABP1_HUMAN relationship: has_participant CCO:B0056099 ! ELAV1_HUMAN relationship: has_participant CCO:B0058648 ! PAIP1_HUMAN [Term] id: CCO:P0002801 name: regulation of receptor-mediated endocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." [GOC:go_curators, GOC:tb] synonym: "regulation of receptor mediated endocytosis" EXACT [GOC:tb] xref: GO:0048259 is_a: CCO:P0001243 ! regulation of endocytosis relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN [Term] id: CCO:P0002802 name: positive regulation of receptor-mediated endocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." [GOC:go_curators, GOC:tb] synonym: "activation of receptor mediated endocytosis" NARROW [] synonym: "positive regulation of receptor mediated endocytosis" EXACT [GOC:tb] synonym: "stimulation of receptor mediated endocytosis" NARROW [] synonym: "up regulation of receptor mediated endocytosis" EXACT [] synonym: "up-regulation of receptor mediated endocytosis" EXACT [] synonym: "upregulation of receptor mediated endocytosis" EXACT [] xref: GO:0048260 is_a: CCO:P0002557 ! positive regulation of endocytosis is_a: CCO:P0002801 ! regulation of receptor-mediated endocytosis relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: has_participant CCO:B0005611 ! CBL_HUMAN relationship: has_participant CCO:B0049794 ! PPT1_HUMAN relationship: has_participant CCO:B0056547 ! ARH_HUMAN [Term] id: CCO:P0002803 name: negative regulation of receptor-mediated endocytosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." [GOC:go_curators] synonym: "down regulation of receptor mediated endocytosis" EXACT [] synonym: "down-regulation of receptor mediated endocytosis" EXACT [] synonym: "downregulation of receptor mediated endocytosis" EXACT [] synonym: "inhibition of receptor mediated endocytosis" NARROW [] synonym: "negative regulation of receptor mediated endocytosis" EXACT [] xref: GO:0048261 is_a: CCO:P0002556 ! negative regulation of endocytosis is_a: CCO:P0002801 ! regulation of receptor-mediated endocytosis relationship: has_participant CCO:B0005337 ! RAC1_HUMAN relationship: has_participant CCO:B0055616 ! ARF6_HUMAN [Term] id: CCO:P0002804 name: regulation of isotype switching to IgE isotypes namespace: biological_process def: "Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes." [GOC:jic] synonym: "regulation of class switch recombination to IgE isotypes" EXACT [] synonym: "regulation of class switching to IgE isotypes" EXACT [] synonym: "regulation of isotype switch recombination to IgE isotypes" EXACT [] xref: GO:0048293 is_a: CCO:P0002284 ! regulation of isotype switching [Term] id: CCO:P0002805 name: negative regulation of isotype switching to IgE isotypes namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of isotype switching to IgE isotypes." [GOC:jic] synonym: "down regulation of isotype switching to IgE isotypes" EXACT [] synonym: "down-regulation of isotype switching to IgE isotypes" EXACT [] synonym: "downregulation of isotype switching to IgE isotypes" EXACT [] synonym: "inhibition of isotype switching to IgE isotypes" NARROW [] synonym: "negative regulation of class switch recombination to IgE isotypes" EXACT [] synonym: "negative regulation of class switching to IgE isotypes" EXACT [] synonym: "negative regulation of isotype switch recombination to IgE isotypes" EXACT [] xref: GO:0048294 is_a: CCO:P0002572 ! negative regulation of isotype switching is_a: CCO:P0002804 ! regulation of isotype switching to IgE isotypes relationship: has_participant CCO:B0001603 ! BCL6_HUMAN [Term] id: CCO:P0002806 name: positive regulation of isotype switching to IgE isotypes namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes." [GOC:jic] synonym: "activation of isotype switching to IgE isotypes" NARROW [] synonym: "positive regulation of class switch recombination to IgE isotypes" EXACT [] synonym: "positive regulation of class switching to IgE isotypes" EXACT [] synonym: "positive regulation of isotype switch recombination to IgE isotypes" EXACT [] synonym: "stimulation of isotype switching to IgE isotypes" NARROW [] synonym: "up regulation of isotype switching to IgE isotypes" EXACT [] synonym: "up-regulation of isotype switching to IgE isotypes" EXACT [] synonym: "upregulation of isotype switching to IgE isotypes" EXACT [] xref: GO:0048295 is_a: CCO:P0002573 ! positive regulation of isotype switching is_a: CCO:P0002804 ! regulation of isotype switching to IgE isotypes relationship: has_participant CCO:B0029685 ! STAT6_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN [Term] id: CCO:P0002807 name: regulation of isotype switching to IgA isotypes namespace: biological_process def: "Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes." [GOC:jic] synonym: "regulation of class switch recombination to IgA isotypes" EXACT [] synonym: "regulation of class switching to IgA isotypes" EXACT [] synonym: "regulation of isotype switch recombination to IgA isotypes" EXACT [] xref: GO:0048296 is_a: CCO:P0002284 ! regulation of isotype switching [Term] id: CCO:P0002808 name: negative regulation of isotype switching to IgA isotypes namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of isotype switching to IgA isotypes." [GOC:jic] synonym: "down regulation of isotype switching to IgA isotypes" EXACT [] synonym: "down-regulation of isotype switching to IgA isotypes" EXACT [] synonym: "downregulation of isotype switching to IgA isotypes" EXACT [] synonym: "inhibition of isotype switching to IgA isotypes" NARROW [] synonym: "negative regulation of class switch recombination to IgA isotypes" EXACT [] synonym: "negative regulation of class switching to IgA isotypes" EXACT [] synonym: "negative regulation of isotype switch recombination to IgA isotypes" EXACT [] xref: GO:0048297 is_a: CCO:P0002572 ! negative regulation of isotype switching is_a: CCO:P0002807 ! regulation of isotype switching to IgA isotypes [Term] id: CCO:P0002809 name: positive regulation of isotype switching to IgA isotypes namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes." [GOC:jic] synonym: "activation of isotype switching to IgA isotypes" NARROW [] synonym: "positive regulation of class switch recombination to IgA isotypes" EXACT [] synonym: "positive regulation of class switching to IgA isotypes" EXACT [] synonym: "positive regulation of isotype switch recombination to IgA isotypes" EXACT [] synonym: "stimulation of isotype switching to IgA isotypes" NARROW [] synonym: "up regulation of isotype switching to IgA isotypes" EXACT [] synonym: "up-regulation of isotype switching to IgA isotypes" EXACT [] synonym: "upregulation of isotype switching to IgA isotypes" EXACT [] xref: GO:0048298 is_a: CCO:P0002573 ! positive regulation of isotype switching is_a: CCO:P0002807 ! regulation of isotype switching to IgA isotypes relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0054674 ! TNF13_HUMAN [Term] id: CCO:P0002810 name: regulation of isotype switching to IgD isotypes namespace: biological_process def: "Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes." [GOC:jic] synonym: "regulation of class switch recombination to IgD isotypes" EXACT [] synonym: "regulation of class switching to IgD isotypes" EXACT [] synonym: "regulation of isotype switch recombination to IgD isotypes" EXACT [] xref: GO:0048299 is_a: CCO:P0002284 ! regulation of isotype switching [Term] id: CCO:P0002811 name: negative regulation of isotype switching to IgD isotypes namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of isotype switching to IgD isotypes." [GOC:jic] synonym: "down regulation of isotype switching to IgD isotypes" EXACT [] synonym: "down-regulation of isotype switching to IgD isotypes" EXACT [] synonym: "downregulation of isotype switching to IgD isotypes" EXACT [] synonym: "inhibition of isotype switching to IgD isotypes" NARROW [] synonym: "negative regulation of class switch recombination to IgD isotypes" EXACT [] synonym: "negative regulation of class switching to IgD isotypes" EXACT [] synonym: "negative regulation of isotype switch recombination to IgD isotypes" EXACT [] xref: GO:0048300 is_a: CCO:P0002572 ! negative regulation of isotype switching is_a: CCO:P0002810 ! regulation of isotype switching to IgD isotypes [Term] id: CCO:P0002812 name: positive regulation of isotype switching to IgD isotypes namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes." [GOC:jic] synonym: "activation of isotype switching to IgD isotypes" NARROW [] synonym: "positive regulation of class switch recombination to IgD isotypes" EXACT [] synonym: "positive regulation of class switching to IgD isotypes" EXACT [] synonym: "positive regulation of isotype switch recombination to IgD isotypes" EXACT [] synonym: "stimulation of isotype switching to IgD isotypes" NARROW [] synonym: "up regulation of isotype switching to IgD isotypes" EXACT [] synonym: "up-regulation of isotype switching to IgD isotypes" EXACT [] synonym: "upregulation of isotype switching to IgD isotypes" EXACT [] xref: GO:0048301 is_a: CCO:P0002573 ! positive regulation of isotype switching is_a: CCO:P0002810 ! regulation of isotype switching to IgD isotypes [Term] id: CCO:P0002813 name: regulation of isotype switching to IgG isotypes namespace: biological_process def: "Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes." [GOC:jic] synonym: "regulation of class switch recombination to IgG isotypes" EXACT [] synonym: "regulation of class switching to IgG isotypes" EXACT [] synonym: "regulation of isotype switch recombination to IgG isotypes" EXACT [] xref: GO:0048302 is_a: CCO:P0002284 ! regulation of isotype switching relationship: has_participant CCO:B0056952 ! I27RA_HUMAN [Term] id: CCO:P0002814 name: negative regulation of isotype switching to IgG isotypes namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of isotype switching to IgG isotypes." [GOC:jic] synonym: "down regulation of isotype switching to IgG isotypes" EXACT [] synonym: "down-regulation of isotype switching to IgG isotypes" EXACT [] synonym: "downregulation of isotype switching to IgG isotypes" EXACT [] synonym: "inhibition of isotype switching to IgG isotypes" NARROW [] synonym: "negative regulation of class switch recombination to IgG isotypes" EXACT [] synonym: "negative regulation of class switching to IgG isotypes" EXACT [] synonym: "negative regulation of isotype switch recombination to IgG isotypes" EXACT [] xref: GO:0048303 is_a: CCO:P0002572 ! negative regulation of isotype switching is_a: CCO:P0002813 ! regulation of isotype switching to IgG isotypes [Term] id: CCO:P0002815 name: positive regulation of isotype switching to IgG isotypes namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes." [GOC:jic] synonym: "activation of isotype switching to IgG isotypes" NARROW [] synonym: "positive regulation of class switch recombination to IgG isotypes" EXACT [] synonym: "positive regulation of class switching to IgG isotypes" EXACT [] synonym: "positive regulation of isotype switch recombination to IgG isotypes" EXACT [] synonym: "stimulation of isotype switching to IgG isotypes" NARROW [] synonym: "up regulation of isotype switching to IgG isotypes" EXACT [] synonym: "up-regulation of isotype switching to IgG isotypes" EXACT [] synonym: "upregulation of isotype switching to IgG isotypes" EXACT [] xref: GO:0048304 is_a: CCO:P0002573 ! positive regulation of isotype switching is_a: CCO:P0002813 ! regulation of isotype switching to IgG isotypes relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0054894 ! IL4_HUMAN relationship: has_participant CCO:B0059213 ! TBX21_HUMAN [Term] id: CCO:P0002816 name: regulation of axial mesodermal cell fate determination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination." [GOC:dgh] xref: GO:0048324 is_a: CCO:P0002822 ! regulation of mesodermal cell fate determination [Term] id: CCO:P0002817 name: negative regulation of axial mesodermal cell fate determination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axial mesoderm cell fate determination." [GOC:dgh] synonym: "down regulation of axial mesodermal cell fate determination" EXACT [] synonym: "down-regulation of axial mesodermal cell fate determination" EXACT [] synonym: "downregulation of axial mesodermal cell fate determination" EXACT [] synonym: "inhibition of axial mesodermal cell fate determination" NARROW [] xref: GO:0048325 is_a: CCO:P0002816 ! regulation of axial mesodermal cell fate determination is_a: CCO:P0002823 ! negative regulation of mesodermal cell fate determination [Term] id: CCO:P0002818 name: positive regulation of axial mesodermal cell fate determination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination." [GOC:dgh] synonym: "activation of axial mesodermal cell fate determination" NARROW [] synonym: "stimulation of axial mesodermal cell fate determination" NARROW [] synonym: "up regulation of axial mesodermal cell fate determination" EXACT [] synonym: "up-regulation of axial mesodermal cell fate determination" EXACT [] synonym: "upregulation of axial mesodermal cell fate determination" EXACT [] xref: GO:0048326 is_a: CCO:P0002816 ! regulation of axial mesodermal cell fate determination is_a: CCO:P0002824 ! positive regulation of mesodermal cell fate determination [Term] id: CCO:P0002819 name: regulation of axial mesodermal cell fate specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification." [GOC:dgh] xref: GO:0048328 is_a: CCO:P0002107 ! regulation of mesodermal cell fate specification [Term] id: CCO:P0002820 name: negative regulation of axial mesodermal cell fate specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axial mesoderm cell fate specification." [GOC:dgh] synonym: "down regulation of axial mesodermal cell fate specification" EXACT [] synonym: "down-regulation of axial mesodermal cell fate specification" EXACT [] synonym: "downregulation of axial mesodermal cell fate specification" EXACT [] synonym: "inhibition of axial mesodermal cell fate specification" NARROW [] xref: GO:0048329 is_a: CCO:P0002108 ! negative regulation of mesodermal cell fate specification is_a: CCO:P0002819 ! regulation of axial mesodermal cell fate specification [Term] id: CCO:P0002821 name: positive regulation of axial mesodermal cell fate specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification." [GOC:dgh] synonym: "activation of axial mesodermal cell fate specification" NARROW [] synonym: "stimulation of axial mesodermal cell fate specification" NARROW [] synonym: "up regulation of axial mesodermal cell fate specification" EXACT [] synonym: "up-regulation of axial mesodermal cell fate specification" EXACT [] synonym: "upregulation of axial mesodermal cell fate specification" EXACT [] xref: GO:0048330 is_a: CCO:P0002819 ! regulation of axial mesodermal cell fate specification is_a: CCO:P0002825 ! positive regulation of mesodermal cell fate specification [Term] id: CCO:P0002822 name: regulation of mesodermal cell fate determination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm cell fate determination." [GOC:dgh] xref: GO:0048334 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002823 name: negative regulation of mesodermal cell fate determination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm cell fate determination." [GOC:dgh] synonym: "down regulation of mesodermal cell fate determination" EXACT [] synonym: "down-regulation of mesodermal cell fate determination" EXACT [] synonym: "downregulation of mesodermal cell fate determination" EXACT [] synonym: "inhibition of mesodermal cell fate determination" NARROW [] xref: GO:0048335 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002822 ! regulation of mesodermal cell fate determination [Term] id: CCO:P0002824 name: positive regulation of mesodermal cell fate determination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination." [GOC:dgh] synonym: "activation of mesodermal cell fate determination" NARROW [] synonym: "stimulation of mesodermal cell fate determination" NARROW [] synonym: "up regulation of mesodermal cell fate determination" EXACT [] synonym: "up-regulation of mesodermal cell fate determination" EXACT [] synonym: "upregulation of mesodermal cell fate determination" EXACT [] xref: GO:0048336 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002822 ! regulation of mesodermal cell fate determination [Term] id: CCO:P0002825 name: positive regulation of mesodermal cell fate specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification." [GOC:dgh] synonym: "activation of mesodermal cell fate specification" NARROW [] synonym: "stimulation of mesodermal cell fate specification" NARROW [] synonym: "up regulation of mesodermal cell fate specification" EXACT [] synonym: "up-regulation of mesodermal cell fate specification" EXACT [] synonym: "upregulation of mesodermal cell fate specification" EXACT [] xref: GO:0048337 is_a: CCO:P0002106 ! positive regulation of cell fate specification is_a: CCO:P0002107 ! regulation of mesodermal cell fate specification [Term] id: CCO:P0002826 name: regulation of paraxial mesodermal cell fate determination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination." [GOC:dgh] xref: GO:0048345 is_a: CCO:P0002822 ! regulation of mesodermal cell fate determination [Term] id: CCO:P0002827 name: positive regulation of paraxial mesodermal cell fate determination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination." [GOC:dgh] synonym: "activation of paraxial mesodermal cell fate determination" NARROW [] synonym: "stimulation of paraxial mesodermal cell fate determination" NARROW [] synonym: "up regulation of paraxial mesodermal cell fate determination" EXACT [] synonym: "up-regulation of paraxial mesodermal cell fate determination" EXACT [] synonym: "upregulation of paraxial mesodermal cell fate determination" EXACT [] xref: GO:0048346 is_a: CCO:P0002824 ! positive regulation of mesodermal cell fate determination is_a: CCO:P0002826 ! regulation of paraxial mesodermal cell fate determination [Term] id: CCO:P0002828 name: negative regulation of paraxial mesodermal cell fate determination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination." [GOC:dgh] synonym: "down regulation of paraxial mesodermal cell fate determination" EXACT [] synonym: "down-regulation of paraxial mesodermal cell fate determination" EXACT [] synonym: "downregulation of paraxial mesodermal cell fate determination" EXACT [] synonym: "inhibition of paraxial mesodermal cell fate determination" NARROW [] xref: GO:0048347 is_a: CCO:P0002823 ! negative regulation of mesodermal cell fate determination is_a: CCO:P0002826 ! regulation of paraxial mesodermal cell fate determination [Term] id: CCO:P0002829 name: regulation of paraxial mesodermal cell fate specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification." [GOC:dgh] xref: GO:0048349 is_a: CCO:P0002107 ! regulation of mesodermal cell fate specification [Term] id: CCO:P0002830 name: positive regulation of paraxial mesodermal cell fate specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification." [GOC:dgh] synonym: "activation of paraxial mesodermal cell fate specification" NARROW [] synonym: "stimulation of paraxial mesodermal cell fate specification" NARROW [] synonym: "up regulation of paraxial mesodermal cell fate specification" EXACT [] synonym: "up-regulation of paraxial mesodermal cell fate specification" EXACT [] synonym: "upregulation of paraxial mesodermal cell fate specification" EXACT [] xref: GO:0048350 is_a: CCO:P0002825 ! positive regulation of mesodermal cell fate specification is_a: CCO:P0002829 ! regulation of paraxial mesodermal cell fate specification [Term] id: CCO:P0002831 name: negative regulation of paraxial mesodermal cell fate specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification." [GOC:dgh] synonym: "down regulation of paraxial mesodermal cell fate specification" EXACT [] synonym: "down-regulation of paraxial mesodermal cell fate specification" EXACT [] synonym: "downregulation of paraxial mesodermal cell fate specification" EXACT [] synonym: "inhibition of paraxial mesodermal cell fate specification" NARROW [] xref: GO:0048351 is_a: CCO:P0002108 ! negative regulation of mesodermal cell fate specification is_a: CCO:P0002829 ! regulation of paraxial mesodermal cell fate specification [Term] id: CCO:P0002832 name: regulation of lateral mesodermal cell fate determination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination." [GOC:jic] synonym: "regulation of lateral mesoderm cell fate determination" EXACT [] synonym: "regulation of lateral plate mesoderm cell fate determination" EXACT [] synonym: "regulation of lateral plate mesodermal cell fate determination" EXACT [] xref: GO:0048374 is_a: CCO:P0002822 ! regulation of mesodermal cell fate determination [Term] id: CCO:P0002833 name: negative regulation of lateral mesodermal cell fate determination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lateral mesoderm cell fate determination." [GOC:jic] synonym: "down regulation of lateral mesodermal cell fate determination" EXACT [] synonym: "down-regulation of lateral mesodermal cell fate determination" EXACT [] synonym: "downregulation of lateral mesodermal cell fate determination" EXACT [] synonym: "inhibition of lateral mesodermal cell fate determination" NARROW [] synonym: "negative regulation of lateral plate mesodermal cell fate determination" EXACT [] xref: GO:0048375 is_a: CCO:P0002823 ! negative regulation of mesodermal cell fate determination is_a: CCO:P0002832 ! regulation of lateral mesodermal cell fate determination [Term] id: CCO:P0002834 name: positive regulation of lateral mesodermal cell fate determination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination." [GOC:jic] synonym: "activation of lateral mesodermal cell fate determination" NARROW [] synonym: "positive regulation of lateral plate mesodermal cell fate determination" EXACT [] synonym: "stimulation of lateral mesodermal cell fate determination" NARROW [] synonym: "up regulation of lateral mesodermal cell fate determination" EXACT [] synonym: "up-regulation of lateral mesodermal cell fate determination" EXACT [] synonym: "upregulation of lateral mesodermal cell fate determination" EXACT [] xref: GO:0048376 is_a: CCO:P0002824 ! positive regulation of mesodermal cell fate determination is_a: CCO:P0002832 ! regulation of lateral mesodermal cell fate determination [Term] id: CCO:P0002835 name: regulation of lateral mesodermal cell fate specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification." [GOC:jic] synonym: "regulation of lateral plate mesodermal cell fate specification" EXACT [] xref: GO:0048378 is_a: CCO:P0002107 ! regulation of mesodermal cell fate specification [Term] id: CCO:P0002836 name: positive regulation of lateral mesodermal cell fate specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification." [GOC:jic] synonym: "activation of lateral mesodermal cell fate specification" NARROW [] synonym: "positive regulation of lateral plate mesodermal cell fate specification" EXACT [] synonym: "stimulation of lateral mesodermal cell fate specification" NARROW [] synonym: "up regulation of lateral mesodermal cell fate specification" EXACT [] synonym: "up-regulation of lateral mesodermal cell fate specification" EXACT [] synonym: "upregulation of lateral mesodermal cell fate specification" EXACT [] xref: GO:0048379 is_a: CCO:P0002825 ! positive regulation of mesodermal cell fate specification is_a: CCO:P0002835 ! regulation of lateral mesodermal cell fate specification [Term] id: CCO:P0002837 name: negative regulation of lateral mesodermal cell fate specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lateral mesoderm cell fate specification." [GOC:jic] synonym: "down regulation of lateral mesodermal cell fate specification" EXACT [] synonym: "down-regulation of lateral mesodermal cell fate specification" EXACT [] synonym: "downregulation of lateral mesodermal cell fate specification" EXACT [] synonym: "inhibition of lateral mesodermal cell fate specification" NARROW [] synonym: "negative regulation of lateral plate mesodermal cell fate specification" EXACT [] xref: GO:0048380 is_a: CCO:P0002108 ! negative regulation of mesodermal cell fate specification is_a: CCO:P0002835 ! regulation of lateral mesodermal cell fate specification [Term] id: CCO:P0002838 name: retinoic acid receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands." [GOC:dgh] synonym: "RAR signaling pathway" EXACT [] synonym: "retinoic acid receptor signalling pathway" EXACT [] xref: GO:0048384 is_a: CCO:P0001281 ! intracellular receptor-mediated signaling pathway relationship: has_participant CCO:B0002157 ! CP26B_HUMAN relationship: has_participant CCO:B0024853 ! RARA_HUMAN relationship: has_participant CCO:B0024886 ! RXRA_HUMAN relationship: has_participant CCO:B0034126 ! RARG_HUMAN relationship: has_participant CCO:B0057127 ! PTF1A_HUMAN [Term] id: CCO:P0002839 name: regulation of retinoic acid receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity." [GOC:dgh] synonym: "regulation of RAR signaling pathway" EXACT [] synonym: "regulation of retinoic acid receptor signalling pathway" EXACT [] xref: GO:0048385 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:P0002840 name: positive regulation of retinoic acid receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity." [GOC:dgh] synonym: "activation of retinoic acid receptor signaling pathway" NARROW [] synonym: "positive regulation of RAR signaling pathway" EXACT [] synonym: "positive regulation of retinoic acid receptor signalling pathway" EXACT [] synonym: "stimulation of retinoic acid receptor signaling pathway" NARROW [] synonym: "up regulation of retinoic acid receptor signaling pathway" EXACT [] synonym: "up-regulation of retinoic acid receptor signaling pathway" EXACT [] synonym: "upregulation of retinoic acid receptor signaling pathway" EXACT [] xref: GO:0048386 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002839 ! regulation of retinoic acid receptor signaling pathway relationship: positively_regulates CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:P0002841 name: negative regulation of retinoic acid receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity." [GOC:dgh] synonym: "down regulation of retinoic acid receptor signaling pathway" EXACT [] synonym: "down-regulation of retinoic acid receptor signaling pathway" EXACT [] synonym: "downregulation of retinoic acid receptor signaling pathway" EXACT [] synonym: "inhibition of retinoic acid receptor signaling pathway" NARROW [] synonym: "negative regulation of RAR signaling pathway" EXACT [] synonym: "negative regulation of RAR signalling pathway" EXACT [] synonym: "negative regulation of retinoic acid receptor signalling pathway" EXACT [] xref: GO:0048387 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002839 ! regulation of retinoic acid receptor signaling pathway relationship: negatively_regulates CCO:P0002838 ! retinoic acid receptor signaling pathway [Term] id: CCO:P0002842 name: regulation of intermediate mesodermal cell fate determination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination." [GOC:dgh] xref: GO:0048395 is_a: CCO:P0002822 ! regulation of mesodermal cell fate determination [Term] id: CCO:P0002843 name: negative regulation of intermediate mesodermal cell fate determination namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination." [GOC:dgh] synonym: "down regulation of intermediate mesodermal cell fate determination" EXACT [] synonym: "down-regulation of intermediate mesodermal cell fate determination" EXACT [] synonym: "downregulation of intermediate mesodermal cell fate determination" EXACT [] synonym: "inhibition of intermediate mesodermal cell fate determination" NARROW [] xref: GO:0048396 is_a: CCO:P0002823 ! negative regulation of mesodermal cell fate determination is_a: CCO:P0002842 ! regulation of intermediate mesodermal cell fate determination [Term] id: CCO:P0002844 name: positive regulation of intermediate mesodermal cell fate determination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination." [GOC:dgh] synonym: "activation of intermediate mesodermal cell fate determination" NARROW [] synonym: "stimulation of intermediate mesodermal cell fate determination" NARROW [] synonym: "up regulation of intermediate mesodermal cell fate determination" EXACT [] synonym: "up-regulation of intermediate mesodermal cell fate determination" EXACT [] synonym: "upregulation of intermediate mesodermal cell fate determination" EXACT [] xref: GO:0048397 is_a: CCO:P0002824 ! positive regulation of mesodermal cell fate determination is_a: CCO:P0002842 ! regulation of intermediate mesodermal cell fate determination [Term] id: CCO:P0002845 name: regulation of intermediate mesodermal cell fate specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification." [GOC:dgh] xref: GO:0048399 is_a: CCO:P0002107 ! regulation of mesodermal cell fate specification [Term] id: CCO:P0002846 name: positive regulation of intermediate mesodermal cell fate specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification." [GOC:dgh] synonym: "activation of intermediate mesodermal cell fate specification" NARROW [] synonym: "stimulation of intermediate mesodermal cell fate specification" NARROW [] synonym: "up regulation of intermediate mesodermal cell fate specification" EXACT [] synonym: "up-regulation of intermediate mesodermal cell fate specification" EXACT [] synonym: "upregulation of intermediate mesodermal cell fate specification" EXACT [] xref: GO:0048400 is_a: CCO:P0002825 ! positive regulation of mesodermal cell fate specification is_a: CCO:P0002845 ! regulation of intermediate mesodermal cell fate specification [Term] id: CCO:P0002847 name: negative regulation of intermediate mesodermal cell fate specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification." [GOC:dgh] synonym: "down regulation of intermediate mesodermal cell fate specification" EXACT [] synonym: "down-regulation of intermediate mesodermal cell fate specification" EXACT [] synonym: "downregulation of intermediate mesodermal cell fate specification" EXACT [] synonym: "inhibition of intermediate mesodermal cell fate specification" NARROW [] xref: GO:0048401 is_a: CCO:P0002108 ! negative regulation of mesodermal cell fate specification is_a: CCO:P0002845 ! regulation of intermediate mesodermal cell fate specification [Term] id: CCO:P0002848 name: replication fork protection namespace: biological_process def: "Any process that prevents the collapse of stalled replication forks." [GOC:vw, PMID:14560029] synonym: "replication fork maintenance" BROAD [] synonym: "replication fork stabilization" BROAD [] xref: GO:0048478 is_a: CCO:P0000813 ! negative regulation of DNA replication relationship: has_participant CCO:B0001649 ! BRCA2_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: has_participant CCO:B0005502 ! BLM_HUMAN [Term] id: CCO:P0002849 name: maintenance of organ identity namespace: biological_process def: "The process by which the identity of an organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tair_curators, PMID:9090883] xref: GO:0048496 is_a: CCO:P0002410 ! negative regulation of cell differentiation relationship: has_participant CCO:B0054636 ! USH2A_HUMAN relationship: has_participant CCO:B0056038 ! IQCB1_HUMAN relationship: has_participant CCO:B0057162 ! NPHP3_HUMAN relationship: has_participant CCO:B0058018 ! GPR98_HUMAN [Term] id: CCO:P0002850 name: maintenance of floral organ identity namespace: biological_process def: "The process by which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized." [GOC:tair_curators, PMID:9090883] xref: GO:0048497 is_a: CCO:P0002849 ! maintenance of organ identity [Term] id: CCO:P0002851 name: regulation of timing of cell differentiation namespace: biological_process def: "The process controlling the timing and/or rate at which relatively unspecialized cells acquire specialized features." [GOC:bf, GOC:jic] synonym: "timing of cell differentiation" RELATED [] xref: GO:0048505 is_a: CCO:P0002409 ! regulation of cell differentiation relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0055986 ! HES1_HUMAN [Term] id: CCO:P0002852 name: positive regulation of cellular process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jic] subset: gosubset_prok synonym: "activation of cellular process" NARROW [] synonym: "positive regulation of cellular physiological process" EXACT [] synonym: "stimulation of cellular process" NARROW [] synonym: "up regulation of cellular process" EXACT [] synonym: "up-regulation of cellular process" EXACT [] synonym: "upregulation of cellular process" EXACT [] xref: GO:0048522 xref: GO:0051242 is_a: CCO:P0002955 ! regulation of cellular process relationship: positively_regulates CCO:P0000887 ! cellular process [Term] id: CCO:P0002853 name: negative regulation of cellular process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jic] subset: gosubset_prok synonym: "down regulation of cellular process" EXACT [] synonym: "down-regulation of cellular process" EXACT [] synonym: "downregulation of cellular process" EXACT [] synonym: "inhibition of cellular process" NARROW [] synonym: "negative regulation of cellular physiological process" EXACT [] xref: GO:0048523 xref: GO:0051243 is_a: CCO:P0002955 ! regulation of cellular process relationship: negatively_regulates CCO:P0000887 ! cellular process [Term] id: CCO:P0002854 name: regulation of pinocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process whereby cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes." [GOC:go_curators] xref: GO:0048548 is_a: CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:P0002855 name: positive regulation of pinocytosis namespace: biological_process def: "Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process whereby cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes." [GOC:go_curators] synonym: "activation of pinocytosis" NARROW [] synonym: "stimulation of pinocytosis" NARROW [] synonym: "up regulation of pinocytosis" EXACT [] synonym: "up-regulation of pinocytosis" EXACT [] synonym: "upregulation of pinocytosis" EXACT [] xref: GO:0048549 is_a: CCO:P0002557 ! positive regulation of endocytosis is_a: CCO:P0002854 ! regulation of pinocytosis relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0049794 ! PPT1_HUMAN [Term] id: CCO:P0002856 name: negative regulation of pinocytosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process whereby cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes." [GOC:go_curators] synonym: "down regulation of pinocytosis" EXACT [] synonym: "down-regulation of pinocytosis" EXACT [] synonym: "downregulation of pinocytosis" EXACT [] synonym: "inhibition of pinocytosis" NARROW [] xref: GO:0048550 is_a: CCO:P0002556 ! negative regulation of endocytosis is_a: CCO:P0002854 ! regulation of pinocytosis [Term] id: CCO:P0002857 name: smooth muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." [CL:0000192, GOC:ebc, PMID:1840698] synonym: "SMC proliferation" EXACT [] xref: GO:0048659 is_a: CCO:P0001749 ! muscle cell proliferation relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0056675 ! MAK10_HUMAN [Term] id: CCO:P0002858 name: regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "regulation of SMC proliferation" EXACT [] xref: GO:0048660 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0002857 ! smooth muscle cell proliferation [Term] id: CCO:P0002859 name: positive regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "activation of smooth muscle cell proliferation" NARROW [] synonym: "positive regulation of SMC proliferation" EXACT [] synonym: "stimulation of smooth muscle cell proliferation" NARROW [] synonym: "up regulation of smooth muscle cell proliferation" EXACT [] synonym: "up-regulation of smooth muscle cell proliferation" EXACT [] synonym: "upregulation of smooth muscle cell proliferation" EXACT [] xref: GO:0048661 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0002858 ! regulation of smooth muscle cell proliferation relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0021417 ! CALRL_HUMAN relationship: has_participant CCO:B0021671 ! HBEGF_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0048975 ! TGM2_HUMAN relationship: has_participant CCO:B0054926 ! ELNE_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0059386 ! NOX1_HUMAN relationship: positively_regulates CCO:P0002857 ! smooth muscle cell proliferation [Term] id: CCO:P0002860 name: negative regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "down regulation of smooth muscle cell proliferation" EXACT [] synonym: "down-regulation of smooth muscle cell proliferation" EXACT [] synonym: "downregulation of smooth muscle cell proliferation" EXACT [] synonym: "inhibition of smooth muscle cell proliferation" NARROW [] synonym: "negative regulation of SMC proliferation" EXACT [] xref: GO:0048662 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0002858 ! regulation of smooth muscle cell proliferation relationship: has_participant CCO:B0006002 ! TRIB1_HUMAN relationship: has_participant CCO:B0006220 ! ANGI_HUMAN relationship: has_participant CCO:B0031813 ! IFNG_HUMAN relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: has_participant CCO:B0050997 ! MFN2_HUMAN relationship: has_participant CCO:B0055094 ! IBP3_HUMAN relationship: has_participant CCO:B0055174 ! IBP5_HUMAN relationship: has_participant CCO:B0055215 ! NOS3_HUMAN relationship: has_participant CCO:B0056089 ! SF01_HUMAN relationship: negatively_regulates CCO:P0002857 ! smooth muscle cell proliferation [Term] id: CCO:P0002861 name: regulation of collateral sprouting namespace: biological_process def: "Any process that modulates the frequency, rate or extent of collateral sprouting." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] xref: GO:0048670 is_a: CCO:P0002409 ! regulation of cell differentiation is_a: CCO:P0002948 ! regulation of axonogenesis [Term] id: CCO:P0002862 name: negative regulation of collateral sprouting namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of collateral sprouting." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "down regulation of collateral sprouting" EXACT [] synonym: "down-regulation of collateral sprouting" EXACT [] synonym: "downregulation of collateral sprouting" EXACT [] synonym: "inhibition of collateral sprouting" NARROW [] xref: GO:0048671 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002861 ! regulation of collateral sprouting is_a: CCO:P0002949 ! negative regulation of axonogenesis [Term] id: CCO:P0002863 name: positive regulation of collateral sprouting namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collateral sprouting." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "activation of collateral sprouting" NARROW [] synonym: "stimulation of collateral sprouting" NARROW [] synonym: "up regulation of collateral sprouting" EXACT [] synonym: "up-regulation of collateral sprouting" EXACT [] synonym: "upregulation of collateral sprouting" EXACT [] xref: GO:0048672 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002861 ! regulation of collateral sprouting is_a: CCO:P0002950 ! positive regulation of axonogenesis [Term] id: CCO:P0002864 name: regulation of axon regeneration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axon regeneration." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] xref: GO:0048679 is_a: CCO:P0002948 ! regulation of axonogenesis [Term] id: CCO:P0002865 name: positive regulation of axon regeneration namespace: biological_process def: "Any process that activates, maintains or increases the rate of axon regeneration." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "activation of axon regeneration" NARROW [] synonym: "stimulation of axon regeneration" NARROW [] synonym: "up regulation of axon regeneration" EXACT [] synonym: "up-regulation of axon regeneration" EXACT [] synonym: "upregulation of axon regeneration" EXACT [] xref: GO:0048680 is_a: CCO:P0002864 ! regulation of axon regeneration is_a: CCO:P0002950 ! positive regulation of axonogenesis [Term] id: CCO:P0002866 name: negative regulation of axon regeneration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axon regeneration." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "down regulation of axon regeneration" EXACT [] synonym: "down-regulation of axon regeneration" EXACT [] synonym: "downregulation of axon regeneration" EXACT [] synonym: "inhibition of axon regeneration" NARROW [] xref: GO:0048681 is_a: CCO:P0002864 ! regulation of axon regeneration is_a: CCO:P0002949 ! negative regulation of axonogenesis relationship: has_participant CCO:B0039858 ! KLK8_HUMAN [Term] id: CCO:P0002867 name: regulation of collateral sprouting of intact axon in response to injury namespace: biological_process def: "Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] xref: GO:0048683 is_a: CCO:P0002861 ! regulation of collateral sprouting is_a: CCO:P0002864 ! regulation of axon regeneration [Term] id: CCO:P0002868 name: positive regulation of collateral sprouting of intact axon in response to injury namespace: biological_process def: "Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "activation of collateral sprouting of intact axon in response to injury" NARROW [] synonym: "stimulation of collateral sprouting of intact axon in response to injury" NARROW [] synonym: "up regulation of collateral sprouting of intact axon in response to injury" EXACT [] synonym: "up-regulation of collateral sprouting of intact axon in response to injury" EXACT [] synonym: "upregulation of collateral sprouting of intact axon in response to injury" EXACT [] xref: GO:0048684 is_a: CCO:P0002863 ! positive regulation of collateral sprouting is_a: CCO:P0002865 ! positive regulation of axon regeneration is_a: CCO:P0002867 ! regulation of collateral sprouting of intact axon in response to injury [Term] id: CCO:P0002869 name: negative regulation of collateral sprouting of intact axon in response to injury namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "down regulation of collateral sprouting of intact axon in response to injury" EXACT [] synonym: "down-regulation of collateral sprouting of intact axon in response to injury" EXACT [] synonym: "downregulation of collateral sprouting of intact axon in response to injury" EXACT [] synonym: "inhibition of collateral sprouting of intact axon in response to injury" NARROW [] xref: GO:0048685 is_a: CCO:P0002862 ! negative regulation of collateral sprouting is_a: CCO:P0002866 ! negative regulation of axon regeneration is_a: CCO:P0002867 ! regulation of collateral sprouting of intact axon in response to injury [Term] id: CCO:P0002870 name: regulation of sprouting of injured axon namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] xref: GO:0048686 is_a: CCO:P0002864 ! regulation of axon regeneration [Term] id: CCO:P0002871 name: positive regulation of sprouting of injured axon namespace: biological_process def: "Any process that activates, maintains or increases the rate of sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "activation of sprouting of injured axon" NARROW [] synonym: "stimulation of sprouting of injured axon" NARROW [] synonym: "up regulation of sprouting of injured axon" EXACT [] synonym: "up-regulation of sprouting of injured axon" EXACT [] synonym: "upregulation of sprouting of injured axon" EXACT [] xref: GO:0048687 is_a: CCO:P0002865 ! positive regulation of axon regeneration is_a: CCO:P0002870 ! regulation of sprouting of injured axon [Term] id: CCO:P0002872 name: negative regulation of sprouting of injured axon namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "down regulation of sprouting of injured axon" EXACT [] synonym: "down-regulation of sprouting of injured axon" EXACT [] synonym: "downregulation of sprouting of injured axon" EXACT [] synonym: "inhibition of sprouting of injured axon" NARROW [] xref: GO:0048688 is_a: CCO:P0002866 ! negative regulation of axon regeneration is_a: CCO:P0002870 ! regulation of sprouting of injured axon [Term] id: CCO:P0002873 name: regulation of axon extension involved in regeneration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axon extension involved in regeneration." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] xref: GO:0048690 is_a: CCO:P0001276 ! regulation of axon extension is_a: CCO:P0002870 ! regulation of sprouting of injured axon [Term] id: CCO:P0002874 name: positive regulation of axon extension involved in regeneration namespace: biological_process def: "Any process that activates, maintains or increases the rate of axon extension involved in regeneration." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "activation of axon extension involved in regeneration" NARROW [] synonym: "stimulation of axon extension involved in regeneration" NARROW [] synonym: "up regulation of axon extension involved in regeneration" EXACT [] synonym: "up-regulation of axon extension involved in regeneration" EXACT [] synonym: "upregulation of axon extension involved in regeneration" EXACT [] xref: GO:0048691 is_a: CCO:P0002548 ! positive regulation of axon extension is_a: CCO:P0002871 ! positive regulation of sprouting of injured axon is_a: CCO:P0002873 ! regulation of axon extension involved in regeneration [Term] id: CCO:P0002875 name: negative regulation of axon extension involved in regeneration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axon extension involved in regeneration." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "down regulation of axon extension involved in regeneration" EXACT [] synonym: "down-regulation of axon extension involved in regeneration" EXACT [] synonym: "downregulation of axon extension involved in regeneration" EXACT [] synonym: "inhibition of axon extension involved in regeneration" NARROW [] xref: GO:0048692 is_a: CCO:P0001277 ! negative regulation of axon extension is_a: CCO:P0002872 ! negative regulation of sprouting of injured axon is_a: CCO:P0002873 ! regulation of axon extension involved in regeneration [Term] id: CCO:P0002876 name: regulation of collateral sprouting of injured axon namespace: biological_process def: "Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] xref: GO:0048693 is_a: CCO:P0002861 ! regulation of collateral sprouting is_a: CCO:P0002870 ! regulation of sprouting of injured axon [Term] id: CCO:P0002877 name: positive regulation of collateral sprouting of injured axon namespace: biological_process def: "Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "activation of collateral sprouting of injured axon" NARROW [] synonym: "stimulation of collateral sprouting of injured axon" NARROW [] synonym: "up regulation of collateral sprouting of injured axon" EXACT [] synonym: "up-regulation of collateral sprouting of injured axon" EXACT [] synonym: "upregulation of collateral sprouting of injured axon" EXACT [] xref: GO:0048694 is_a: CCO:P0002863 ! positive regulation of collateral sprouting is_a: CCO:P0002871 ! positive regulation of sprouting of injured axon is_a: CCO:P0002876 ! regulation of collateral sprouting of injured axon [Term] id: CCO:P0002878 name: negative regulation of collateral sprouting of injured axon namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of collateral sprouting of an injured axon." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "down regulation of collateral sprouting of injured axon" EXACT [] synonym: "down-regulation of collateral sprouting of injured axon" EXACT [] synonym: "downregulation of collateral sprouting of injured axon" EXACT [] synonym: "inhibition of collateral sprouting of injured axon" NARROW [] xref: GO:0048695 is_a: CCO:P0002862 ! negative regulation of collateral sprouting is_a: CCO:P0002872 ! negative regulation of sprouting of injured axon is_a: CCO:P0002876 ! regulation of collateral sprouting of injured axon [Term] id: CCO:P0002879 name: regulation of collateral sprouting in the absence of injury namespace: biological_process def: "Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] xref: GO:0048696 is_a: CCO:P0002861 ! regulation of collateral sprouting [Term] id: CCO:P0002880 name: positive regulation of collateral sprouting in the absence of injury namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "activation of collateral sprouting in the absence of injury" NARROW [] synonym: "stimulation of collateral sprouting in the absence of injury" NARROW [] synonym: "up regulation of collateral sprouting in the absence of injury" EXACT [] synonym: "up-regulation of collateral sprouting in the absence of injury" EXACT [] synonym: "upregulation of collateral sprouting in the absence of injury" EXACT [] xref: GO:0048697 is_a: CCO:P0002863 ! positive regulation of collateral sprouting is_a: CCO:P0002879 ! regulation of collateral sprouting in the absence of injury [Term] id: CCO:P0002881 name: negative regulation of collateral sprouting in the absence of injury namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of collateral sprouting in the absence of injury." [GOC:dgh, GOC:dph, GOC:jic, GOC:lm] synonym: "down regulation of collateral sprouting in the absence of injury" EXACT [] synonym: "down-regulation of collateral sprouting in the absence of injury" EXACT [] synonym: "downregulation of collateral sprouting in the absence of injury" EXACT [] synonym: "inhibition of collateral sprouting in the absence of injury" NARROW [] xref: GO:0048698 is_a: CCO:P0002862 ! negative regulation of collateral sprouting is_a: CCO:P0002879 ! regulation of collateral sprouting in the absence of injury [Term] id: CCO:P0002882 name: regulation of astrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of astrocyte differentiation." [GOC:vp, PMID:15139015] xref: GO:0048710 is_a: CCO:P0002493 ! regulation of glial cell differentiation [Term] id: CCO:P0002883 name: positive regulation of astrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of astrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "activation of astrocyte differentiation" NARROW [] synonym: "stimulation of astrocyte differentiation" NARROW [] synonym: "up regulation of astrocyte differentiation" EXACT [] synonym: "up-regulation of astrocyte differentiation" EXACT [] synonym: "upregulation of astrocyte differentiation" EXACT [] xref: GO:0048711 is_a: CCO:P0002495 ! positive regulation of glial cell differentiation is_a: CCO:P0002882 ! regulation of astrocyte differentiation relationship: has_participant CCO:B0001515 ! BMP2_HUMAN relationship: has_participant CCO:B0016149 ! PRP19_HUMAN [Term] id: CCO:P0002884 name: negative regulation of astrocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "down regulation of astrocyte differentiation" EXACT [] synonym: "down-regulation of astrocyte differentiation" EXACT [] synonym: "downregulation of astrocyte differentiation" EXACT [] synonym: "inhibition of astrocyte differentiation" NARROW [] xref: GO:0048712 is_a: CCO:P0002494 ! negative regulation of glial cell differentiation is_a: CCO:P0002882 ! regulation of astrocyte differentiation relationship: has_participant CCO:B0022226 ! ID4_HUMAN [Term] id: CCO:P0002885 name: regulation of oligodendrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] xref: GO:0048713 is_a: CCO:P0002493 ! regulation of glial cell differentiation [Term] id: CCO:P0002886 name: positive regulation of oligodendrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "activation of oligodendrocyte differentiation" NARROW [] synonym: "stimulation of oligodendrocyte differentiation" NARROW [] synonym: "up regulation of oligodendrocyte differentiation" EXACT [] synonym: "up-regulation of oligodendrocyte differentiation" EXACT [] synonym: "upregulation of oligodendrocyte differentiation" EXACT [] xref: GO:0048714 is_a: CCO:P0002495 ! positive regulation of glial cell differentiation is_a: CCO:P0002885 ! regulation of oligodendrocyte differentiation relationship: has_participant CCO:B0058291 ! ZN488_HUMAN [Term] id: CCO:P0002887 name: negative regulation of oligodendrocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "down regulation of oligodendrocyte differentiation" EXACT [] synonym: "down-regulation of oligodendrocyte differentiation" EXACT [] synonym: "downregulation of oligodendrocyte differentiation" EXACT [] synonym: "inhibition of oligodendrocyte differentiation" NARROW [] xref: GO:0048715 is_a: CCO:P0002494 ! negative regulation of glial cell differentiation is_a: CCO:P0002885 ! regulation of oligodendrocyte differentiation relationship: has_participant CCO:B0001542 ! NF1_HUMAN [Term] id: CCO:P0002888 name: regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibres are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jic, GOC:mtg_muscle, GOC:sm] synonym: "regulation of skeletal muscle fibre development" EXACT [] synonym: "regulation of skeletal myofiber development" EXACT [] synonym: "regulation of skeletal myofibre development" EXACT [] xref: GO:0048742 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0002889 name: positive regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibres are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jic, GOC:lm, GOC:mtg_muscle] synonym: "activation of skeletal muscle fiber development" NARROW [] synonym: "positive regulation of skeletal muscle fibre development" EXACT [] synonym: "positive regulation of skeletal myofiber development" EXACT [] synonym: "positive regulation of skeletal myofibre development" EXACT [] synonym: "stimulation of skeletal muscle fiber development" NARROW [] synonym: "up regulation of skeletal muscle fiber development" EXACT [] synonym: "up-regulation of skeletal muscle fiber development" EXACT [] synonym: "upregulation of skeletal muscle fiber development" EXACT [] xref: GO:0048743 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0002888 ! regulation of skeletal muscle fiber development [Term] id: CCO:P0002890 name: negative regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibres are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jic, GOC:lm, GOC:mtg_muscle] synonym: "down regulation of skeletal muscle fiber development" EXACT [] synonym: "down-regulation of skeletal muscle fiber development" EXACT [] synonym: "downregulation of skeletal muscle fiber development" EXACT [] synonym: "inhibition of skeletal muscle fiber development" NARROW [] synonym: "negative regulation of skeletal muscle fibre development" EXACT [] synonym: "negative regulation of skeletal myofiber development" EXACT [] synonym: "negative regulation of skeletal myofibre development" EXACT [] xref: GO:0048744 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0002888 ! regulation of skeletal muscle fiber development [Term] id: CCO:P0002891 name: regulation of leucophore differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leucophore differentiation." [GOC:mh] xref: GO:0048775 is_a: CCO:P0002990 ! regulation of pigment cell differentiation [Term] id: CCO:P0002892 name: negative regulation of leucophore differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of leucophore differentiation." [GOC:mh] synonym: "down regulation of leucophore differentiation" EXACT [] synonym: "down-regulation of leucophore differentiation" EXACT [] synonym: "downregulation of leucophore differentiation" EXACT [] synonym: "inhibition of leucophore differentiation" NARROW [] xref: GO:0048776 is_a: CCO:P0002891 ! regulation of leucophore differentiation is_a: CCO:P0002995 ! negative regulation of pigment cell differentiation [Term] id: CCO:P0002893 name: positive regulation of leucophore differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leucophore differentiation." [GOC:mh] synonym: "activation of leucophore differentiation" NARROW [] synonym: "stimulation of leucophore differentiation" NARROW [] synonym: "up regulation of leucophore differentiation" EXACT [] synonym: "up-regulation of leucophore differentiation" EXACT [] synonym: "upregulation of leucophore differentiation" EXACT [] xref: GO:0048777 is_a: CCO:P0002891 ! regulation of leucophore differentiation is_a: CCO:P0002996 ! positive regulation of pigment cell differentiation [Term] id: CCO:P0002894 name: regulation of erythrophore differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrophore differentiation." [GOC:mh] xref: GO:0048778 is_a: CCO:P0002990 ! regulation of pigment cell differentiation [Term] id: CCO:P0002895 name: negative regulation of erythrophore differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrophore differentiation." [GOC:mh] synonym: "down regulation of erythrophore differentiation" EXACT [] synonym: "down-regulation of erythrophore differentiation" EXACT [] synonym: "downregulation of erythrophore differentiation" EXACT [] synonym: "inhibition of erythrophore differentiation" NARROW [] xref: GO:0048779 is_a: CCO:P0002894 ! regulation of erythrophore differentiation is_a: CCO:P0002995 ! negative regulation of pigment cell differentiation [Term] id: CCO:P0002896 name: positive regulation of erythrophore differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrophore differentiation." [GOC:mh] synonym: "activation of erythrophore differentiation" NARROW [] synonym: "stimulation of erythrophore differentiation" NARROW [] synonym: "up regulation of erythrophore differentiation" EXACT [] synonym: "up-regulation of erythrophore differentiation" EXACT [] synonym: "upregulation of erythrophore differentiation" EXACT [] xref: GO:0048780 is_a: CCO:P0002894 ! regulation of erythrophore differentiation is_a: CCO:P0002996 ! positive regulation of pigment cell differentiation [Term] id: CCO:P0002897 name: regulation of cyanophore differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cyanophore differentiation." [GOC:mh] xref: GO:0048781 is_a: CCO:P0002990 ! regulation of pigment cell differentiation [Term] id: CCO:P0002898 name: negative regulation of cyanophore differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cyanophore differentiation." [GOC:mh] synonym: "down regulation of cyanophore differentiation" EXACT [] synonym: "down-regulation of cyanophore differentiation" EXACT [] synonym: "downregulation of cyanophore differentiation" EXACT [] synonym: "inhibition of cyanophore differentiation" NARROW [] xref: GO:0048782 is_a: CCO:P0002897 ! regulation of cyanophore differentiation is_a: CCO:P0002995 ! negative regulation of pigment cell differentiation [Term] id: CCO:P0002899 name: positive regulation of cyanophore differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cyanophore differentiation." [GOC:mh] synonym: "activation of cyanophore differentiation" NARROW [] synonym: "stimulation of cyanophore differentiation" NARROW [] synonym: "up regulation of cyanophore differentiation" EXACT [] synonym: "up-regulation of cyanophore differentiation" EXACT [] synonym: "upregulation of cyanophore differentiation" EXACT [] xref: GO:0048783 is_a: CCO:P0002897 ! regulation of cyanophore differentiation is_a: CCO:P0002996 ! positive regulation of pigment cell differentiation [Term] id: CCO:P0002900 name: regulation of dendrite morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendrite morphogenesis." [GOC:ai] xref: GO:0048814 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0032804 ! ACHA3_HUMAN relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN relationship: part_of CCO:P0002951 ! regulation of dendrite development [Term] id: CCO:P0002901 name: regulation of axon extension involved in axon guidance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance." [GOC:devbiol] xref: GO:0048841 is_a: CCO:P0001276 ! regulation of axon extension [Term] id: CCO:P0002902 name: positive regulation of axon extension involved in axon guidance namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance." [GOC:devbiol] synonym: "activation of axon extension involved in axon guidance" NARROW [] synonym: "stimulation of axon extension involved in axon guidance" NARROW [] synonym: "up regulation of axon extension involved in axon guidance" EXACT [] synonym: "up-regulation of axon extension involved in axon guidance" EXACT [] synonym: "upregulation of axon extension involved in axon guidance" EXACT [] xref: GO:0048842 is_a: CCO:P0002548 ! positive regulation of axon extension is_a: CCO:P0002901 ! regulation of axon extension involved in axon guidance [Term] id: CCO:P0002903 name: negative regulation of axon extension involved in axon guidance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axon extension involved in axon guidance." [GOC:devbiol] synonym: "down regulation of axon extension involved in axon guidance" EXACT [] synonym: "down-regulation of axon extension involved in axon guidance" EXACT [] synonym: "downregulation of axon extension involved in axon guidance" EXACT [] synonym: "inhibition of axon extension involved in axon guidance" NARROW [] xref: GO:0048843 is_a: CCO:P0001277 ! negative regulation of axon extension is_a: CCO:P0002901 ! regulation of axon extension involved in axon guidance relationship: has_participant CCO:B0055480 ! PLXA3_HUMAN [Term] id: CCO:P0002904 name: glioblast cell division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a glioblast into daughter cells." [GOC:devbiol] xref: GO:0048860 is_a: CCO:P0003077 ! cell division [Term] id: CCO:P0002905 name: leukemia inhibitory factor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a leukemia inhibitory factor receptor binding to one of its physiological ligands." [GOC:devbiol] synonym: "leukemia inhibitory factor signalling pathway" EXACT [] xref: GO:0048861 is_a: CCO:P0000710 ! enzyme linked receptor protein signaling pathway [Term] id: CCO:P0002906 name: neuromast deposition namespace: biological_process def: "The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line." [PMID:15018940] xref: GO:0048885 is_a: CCO:P0001259 ! negative regulation of cell migration [Term] id: CCO:P0002907 name: anterior lateral line neuromast deposition namespace: biological_process def: "The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line." [PMID:15832385] xref: GO:0048902 is_a: CCO:P0002906 ! neuromast deposition [Term] id: CCO:P0002908 name: posterior lateral line neuromast deposition namespace: biological_process def: "The process by which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line." [PMID:15832385] xref: GO:0048922 is_a: CCO:P0002906 ! neuromast deposition [Term] id: CCO:P0002909 name: regulation of catecholamine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." [GOC:ai] xref: GO:0050433 is_a: CCO:P0002749 ! regulation of neurotransmitter secretion [Term] id: CCO:P0002910 name: positive regulation of viral transcription namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of viral transcription." [GOC:ai] synonym: "activation of viral transcription" NARROW [] synonym: "stimulation of viral transcription" NARROW [] synonym: "up regulation of viral transcription" EXACT [] synonym: "up-regulation of viral transcription" EXACT [] synonym: "upregulation of viral transcription" EXACT [] xref: GO:0050434 xref: Reactome:167246 is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent is_a: CCO:P0002738 ! regulation of viral transcription relationship: has_participant CCO:B0058398 ! RSF1_HUMAN relationship: has_participant CCO:B0059043 ! MDFIC_HUMAN [Term] id: CCO:P0002911 name: regulation of homocysteine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid." [GOC:ai] subset: gosubset_prok synonym: "regulation of Hcy metabolic process" EXACT [] synonym: "regulation of Hcy metabolism" EXACT [] synonym: "regulation of homocysteine metabolism" EXACT [] xref: GO:0050666 is_a: CCO:P0001415 ! regulation of sulfur amino acid metabolic process relationship: has_participant CCO:B0058123 ! BHMT1_HUMAN [Term] id: CCO:P0002912 name: positive regulation of homocysteine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine." [GOC:ai] subset: gosubset_prok synonym: "activation of homocysteine metabolic process" NARROW [] synonym: "positive regulation of Hcy metabolic process" EXACT [] synonym: "positive regulation of Hcy metabolism" EXACT [] synonym: "positive regulation of homocysteine metabolism" EXACT [] synonym: "stimulation of homocysteine metabolic process" NARROW [] synonym: "up regulation of homocysteine metabolic process" EXACT [] synonym: "up-regulation of homocysteine metabolic process" EXACT [] synonym: "upregulation of homocysteine metabolic process" EXACT [] xref: GO:0050668 is_a: CCO:P0001417 ! positive regulation of sulfur amino acid metabolic process is_a: CCO:P0002911 ! regulation of homocysteine metabolic process [Term] id: CCO:P0002913 name: negative regulation of homocysteine metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine." [GOC:ai] subset: gosubset_prok synonym: "down regulation of homocysteine metabolic process" EXACT [] synonym: "down-regulation of homocysteine metabolic process" EXACT [] synonym: "downregulation of homocysteine metabolic process" EXACT [] synonym: "inhibition of homocysteine metabolic process" NARROW [] synonym: "negative regulation of Hcy metabolic process" EXACT [] synonym: "negative regulation of Hcy metabolism" EXACT [] synonym: "negative regulation of homocysteine metabolism" EXACT [] xref: GO:0050669 is_a: CCO:P0001416 ! negative regulation of sulfur amino acid metabolic process is_a: CCO:P0002911 ! regulation of homocysteine metabolic process [Term] id: CCO:P0002914 name: regulation of lymphocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." [GOC:ai] xref: GO:0050670 is_a: CCO:P0001725 ! regulation of mononuclear cell proliferation is_a: CCO:P0003065 ! regulation of lymphocyte activation relationship: regulates CCO:P0002724 ! lymphocyte proliferation [Term] id: CCO:P0002915 name: positive regulation of lymphocyte proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "activation of lymphocyte proliferation" NARROW [] synonym: "stimulation of lymphocyte proliferation" NARROW [] synonym: "up regulation of lymphocyte proliferation" EXACT [] synonym: "up-regulation of lymphocyte proliferation" EXACT [] synonym: "upregulation of lymphocyte proliferation" EXACT [] xref: GO:0050671 is_a: CCO:P0001727 ! positive regulation of mononuclear cell proliferation is_a: CCO:P0002914 ! regulation of lymphocyte proliferation is_a: CCO:P0003067 ! positive regulation of lymphocyte activation relationship: has_participant CCO:B0043824 ! IL12B_HUMAN relationship: positively_regulates CCO:P0002724 ! lymphocyte proliferation [Term] id: CCO:P0002916 name: negative regulation of lymphocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "down regulation of lymphocyte proliferation" EXACT [] synonym: "down-regulation of lymphocyte proliferation" EXACT [] synonym: "downregulation of lymphocyte proliferation" EXACT [] synonym: "inhibition of lymphocyte proliferation" NARROW [] xref: GO:0050672 is_a: CCO:P0001726 ! negative regulation of mononuclear cell proliferation is_a: CCO:P0002914 ! regulation of lymphocyte proliferation is_a: CCO:P0003066 ! negative regulation of lymphocyte activation relationship: has_participant CCO:B0054322 ! LST1_HUMAN relationship: has_participant CCO:B0055148 ! GALA_HUMAN relationship: negatively_regulates CCO:P0002724 ! lymphocyte proliferation [Term] id: CCO:P0002917 name: epithelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0050673 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0054431 ! FOXN1_HUMAN relationship: has_participant CCO:B0054977 ! KIT_HUMAN [Term] id: CCO:P0002918 name: urothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria." [ISBN:0721662544 "Dorland's Illustrated Medical Dictionary"] xref: GO:0050674 is_a: CCO:P0002917 ! epithelial cell proliferation relationship: has_participant CCO:B0001379 ! FGF10_HUMAN [Term] id: CCO:P0002919 name: regulation of urothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of urothelial cell proliferation." [GOC:ai] xref: GO:0050675 is_a: CCO:P0002922 ! regulation of epithelial cell proliferation relationship: regulates CCO:P0002918 ! urothelial cell proliferation [Term] id: CCO:P0002920 name: negative regulation of urothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation." [GOC:ai] synonym: "down regulation of urothelial cell proliferation" EXACT [] synonym: "down-regulation of urothelial cell proliferation" EXACT [] synonym: "downregulation of urothelial cell proliferation" EXACT [] synonym: "inhibition of urothelial cell proliferation" NARROW [] xref: GO:0050676 is_a: CCO:P0002919 ! regulation of urothelial cell proliferation is_a: CCO:P0002924 ! negative regulation of epithelial cell proliferation relationship: negatively_regulates CCO:P0002918 ! urothelial cell proliferation [Term] id: CCO:P0002921 name: positive regulation of urothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of urothelial cell proliferation." [GOC:ai] synonym: "activation of urothelial cell proliferation" NARROW [] synonym: "stimulation of urothelial cell proliferation" NARROW [] synonym: "up regulation of urothelial cell proliferation" EXACT [] synonym: "up-regulation of urothelial cell proliferation" EXACT [] synonym: "upregulation of urothelial cell proliferation" EXACT [] xref: GO:0050677 is_a: CCO:P0002919 ! regulation of urothelial cell proliferation is_a: CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: has_participant CCO:B0001379 ! FGF10_HUMAN relationship: positively_regulates CCO:P0002918 ! urothelial cell proliferation [Term] id: CCO:P0002922 name: regulation of epithelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." [GOC:ai] xref: GO:0050678 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0002917 ! epithelial cell proliferation [Term] id: CCO:P0002923 name: positive regulation of epithelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "activation of epithelial cell proliferation" NARROW [] synonym: "stimulation of epithelial cell proliferation" NARROW [] synonym: "up regulation of epithelial cell proliferation" EXACT [] synonym: "up-regulation of epithelial cell proliferation" EXACT [] synonym: "upregulation of epithelial cell proliferation" EXACT [] xref: GO:0050679 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0002922 ! regulation of epithelial cell proliferation relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001502 ! FGF2_HUMAN relationship: has_participant CCO:B0001524 ! NDKA_HUMAN relationship: has_participant CCO:B0001546 ! NDKB_HUMAN relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0005437 ! BMR1A_HUMAN relationship: has_participant CCO:B0005540 ! ERBB2_HUMAN relationship: has_participant CCO:B0005870 ! TGFA_HUMAN relationship: has_participant CCO:B0005967 ! LAMB1_HUMAN relationship: has_participant CCO:B0016727 ! FOXE3_HUMAN relationship: has_participant CCO:B0018677 ! TBX18_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN relationship: has_participant CCO:B0054985 ! LAMC1_HUMAN relationship: has_participant CCO:B0055184 ! LAMA1_HUMAN relationship: has_participant CCO:B0056004 ! IHH_HUMAN relationship: positively_regulates CCO:P0002917 ! epithelial cell proliferation [Term] id: CCO:P0002924 name: negative regulation of epithelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "down regulation of epithelial cell proliferation" EXACT [] synonym: "down-regulation of epithelial cell proliferation" EXACT [] synonym: "downregulation of epithelial cell proliferation" EXACT [] synonym: "inhibition of epithelial cell proliferation" NARROW [] xref: GO:0050680 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0002922 ! regulation of epithelial cell proliferation relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001616 ! CDN2B_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0001640 ! CDN1C_HUMAN relationship: has_participant CCO:B0001672 ! GAS1_HUMAN relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0001766 ! RUNX3_HUMAN relationship: has_participant CCO:B0006204 ! MAGD1_HUMAN relationship: has_participant CCO:B0021644 ! K2C4_HUMAN relationship: negatively_regulates CCO:P0002917 ! epithelial cell proliferation [Term] id: CCO:P0002925 name: regulation of mRNA processing namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide." [GOC:ai] subset: gosubset_prok xref: GO:0050684 is_a: CCO:P0003068 ! regulation of RNA metabolic process relationship: has_participant CCO:B0001540 ! CD2L1_HUMAN relationship: has_participant CCO:B0002061 ! SRPK1_HUMAN relationship: has_participant CCO:B0002241 ! CD2L2_HUMAN [Term] id: CCO:P0002926 name: positive regulation of mRNA processing namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mRNA processing." [GOC:ai] subset: gosubset_prok synonym: "activation of mRNA processing" NARROW [] synonym: "stimulation of mRNA processing" NARROW [] synonym: "up regulation of mRNA processing" EXACT [] synonym: "up-regulation of mRNA processing" EXACT [] synonym: "upregulation of mRNA processing" EXACT [] xref: GO:0050685 is_a: CCO:P0002925 ! regulation of mRNA processing is_a: CCO:P0003070 ! positive regulation of RNA metabolic process [Term] id: CCO:P0002927 name: negative regulation of mRNA processing namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA processing." [GOC:ai] subset: gosubset_prok synonym: "down regulation of mRNA processing" EXACT [] synonym: "down-regulation of mRNA processing" EXACT [] synonym: "downregulation of mRNA processing" EXACT [] synonym: "inhibition of mRNA processing" NARROW [] xref: GO:0050686 is_a: CCO:P0002925 ! regulation of mRNA processing is_a: CCO:P0003069 ! negative regulation of RNA metabolic process [Term] id: CCO:P0002928 name: regulation of interleukin-1 alpha biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha." [GOC:ai] synonym: "regulation of interleukin-1 alpha anabolism" EXACT [] synonym: "regulation of interleukin-1 alpha biosynthesis" EXACT [] synonym: "regulation of interleukin-1 alpha formation" EXACT [] synonym: "regulation of interleukin-1 alpha synthesis" EXACT [] xref: GO:0050721 is_a: CCO:P0002301 ! regulation of interleukin-1 biosynthetic process [Term] id: CCO:P0002929 name: regulation of interleukin-1 beta biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta." [GOC:ai] synonym: "regulation of interleukin-1 beta anabolism" EXACT [] synonym: "regulation of interleukin-1 beta biosynthesis" EXACT [] synonym: "regulation of interleukin-1 beta formation" EXACT [] synonym: "regulation of interleukin-1 beta synthesis" EXACT [] xref: GO:0050722 is_a: CCO:P0002301 ! regulation of interleukin-1 biosynthetic process [Term] id: CCO:P0002930 name: negative regulation of interleukin-1 alpha biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha." [GOC:ai] synonym: "down regulation of interleukin-1 alpha biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-1 alpha biosynthetic process" EXACT [] synonym: "downregulation of interleukin-1 alpha biosynthetic process" EXACT [] synonym: "inhibition of interleukin-1 alpha biosynthetic process" NARROW [] synonym: "negative regulation of interleukin-1 alpha anabolism" EXACT [] synonym: "negative regulation of interleukin-1 alpha biosynthesis" EXACT [] synonym: "negative regulation of interleukin-1 alpha formation" EXACT [] synonym: "negative regulation of interleukin-1 alpha synthesis" EXACT [] xref: GO:0050723 is_a: CCO:P0002302 ! negative regulation of interleukin-1 biosynthetic process is_a: CCO:P0002928 ! regulation of interleukin-1 alpha biosynthetic process [Term] id: CCO:P0002931 name: negative regulation of interleukin-1 beta biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta." [GOC:ai] synonym: "down regulation of interleukin-1 beta biosynthetic process" EXACT [] synonym: "down-regulation of interleukin-1 beta biosynthetic process" EXACT [] synonym: "downregulation of interleukin-1 beta biosynthetic process" EXACT [] synonym: "inhibition of interleukin-1 beta biosynthetic process" NARROW [] synonym: "negative regulation of interleukin-1 beta anabolism" EXACT [] synonym: "negative regulation of interleukin-1 beta biosynthesis" EXACT [] synonym: "negative regulation of interleukin-1 beta formation" EXACT [] synonym: "negative regulation of interleukin-1 beta synthesis" EXACT [] xref: GO:0050724 is_a: CCO:P0002302 ! negative regulation of interleukin-1 biosynthetic process is_a: CCO:P0002929 ! regulation of interleukin-1 beta biosynthetic process [Term] id: CCO:P0002932 name: positive regulation of interleukin-1 beta biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta." [GOC:ai] synonym: "activation of interleukin-1 beta biosynthetic process" NARROW [] synonym: "positive regulation of interleukin-1 beta anabolism" EXACT [] synonym: "positive regulation of interleukin-1 beta biosynthesis" EXACT [] synonym: "positive regulation of interleukin-1 beta formation" EXACT [] synonym: "positive regulation of interleukin-1 beta synthesis" EXACT [] synonym: "stimulation of interleukin-1 beta biosynthetic process" NARROW [] synonym: "up regulation of interleukin-1 beta biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-1 beta biosynthetic process" EXACT [] synonym: "upregulation of interleukin-1 beta biosynthetic process" EXACT [] xref: GO:0050725 is_a: CCO:P0002303 ! positive regulation of interleukin-1 biosynthetic process is_a: CCO:P0002929 ! regulation of interleukin-1 beta biosynthetic process relationship: has_participant CCO:B0055114 ! CAP7_HUMAN relationship: has_participant CCO:B0057234 ! Q86SR2_HUMAN [Term] id: CCO:P0002933 name: positive regulation of interleukin-1 alpha biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha." [GOC:ai] synonym: "activation of interleukin-1 alpha biosynthetic process" NARROW [] synonym: "positive regulation of interleukin-1 alpha anabolism" EXACT [] synonym: "positive regulation of interleukin-1 alpha biosynthesis" EXACT [] synonym: "positive regulation of interleukin-1 alpha formation" EXACT [] synonym: "positive regulation of interleukin-1 alpha synthesis" EXACT [] synonym: "stimulation of interleukin-1 alpha biosynthetic process" NARROW [] synonym: "up regulation of interleukin-1 alpha biosynthetic process" EXACT [] synonym: "up-regulation of interleukin-1 alpha biosynthetic process" EXACT [] synonym: "upregulation of interleukin-1 alpha biosynthetic process" EXACT [] xref: GO:0050726 is_a: CCO:P0002303 ! positive regulation of interleukin-1 biosynthetic process is_a: CCO:P0002928 ! regulation of interleukin-1 alpha biosynthetic process [Term] id: CCO:P0002934 name: regulation of peptidyl-tyrosine phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] subset: gosubset_prok xref: GO:0050730 is_a: CCO:P0000500 ! regulation of protein amino acid phosphorylation relationship: has_participant CCO:B0001462 ! EGFR_HUMAN relationship: has_participant CCO:B0001470 ! EGF_HUMAN relationship: has_participant CCO:B0001529 ! KPCA_HUMAN relationship: has_participant CCO:B0020508 ! PGFRB_HUMAN relationship: has_participant CCO:B0033122 ! ITB2_HUMAN [Term] id: CCO:P0002935 name: positive regulation of peptidyl-tyrosine phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] subset: gosubset_prok synonym: "activation of peptidyl-tyrosine phosphorylation" NARROW [] synonym: "stimulation of peptidyl-tyrosine phosphorylation" NARROW [] synonym: "up regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "up-regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "upregulation of peptidyl-tyrosine phosphorylation" EXACT [] xref: GO:0050731 is_a: CCO:P0000502 ! positive regulation of protein amino acid phosphorylation is_a: CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0005836 ! ACK1_HUMAN relationship: has_participant CCO:B0006244 ! TDGF1_HUMAN relationship: has_participant CCO:B0006262 ! CD81_HUMAN relationship: has_participant CCO:B0042830 ! FCERA_HUMAN relationship: has_participant CCO:B0049019 ! IGHM_HUMAN relationship: has_participant CCO:B0054895 ! IL5_HUMAN relationship: has_participant CCO:B0054899 ! IL6_HUMAN relationship: has_participant CCO:B0054931 ! IL3_HUMAN relationship: has_participant CCO:B0055018 ! ONCM_HUMAN relationship: has_participant CCO:B0055030 ! LIF_HUMAN relationship: has_participant CCO:B0055126 ! IL11_HUMAN relationship: has_participant CCO:B0055268 ! CD80_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN [Term] id: CCO:P0002936 name: negative regulation of peptidyl-tyrosine phosphorylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] subset: gosubset_prok synonym: "down regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "down-regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "downregulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "inhibition of peptidyl-tyrosine phosphorylation" NARROW [] xref: GO:0050732 is_a: CCO:P0000501 ! negative regulation of protein amino acid phosphorylation is_a: CCO:P0002934 ! regulation of peptidyl-tyrosine phosphorylation [Term] id: CCO:P0002937 name: positive regulation of lipoprotein metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids." [GOC:ai] subset: gosubset_prok synonym: "activation of lipoprotein metabolic process" NARROW [] synonym: "positive regulation of lipoprotein metabolism" EXACT [] synonym: "stimulation of lipoprotein metabolic process" NARROW [] synonym: "up regulation of lipoprotein metabolic process" EXACT [] synonym: "up-regulation of lipoprotein metabolic process" EXACT [] synonym: "upregulation of lipoprotein metabolic process" EXACT [] xref: GO:0050747 is_a: CCO:P0001574 ! positive regulation of cellular protein metabolic process [Term] id: CCO:P0002938 name: negative regulation of lipoprotein metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids." [GOC:ai] subset: gosubset_prok synonym: "down regulation of lipoprotein metabolic process" EXACT [] synonym: "down-regulation of lipoprotein metabolic process" EXACT [] synonym: "downregulation of lipoprotein metabolic process" EXACT [] synonym: "inhibition of lipoprotein metabolic process" NARROW [] synonym: "negative regulation of lipoprotein metabolism" EXACT [] xref: GO:0050748 is_a: CCO:P0001573 ! negative regulation of cellular protein metabolic process relationship: has_participant CCO:B0054863 ! APOA2_HUMAN [Term] id: CCO:P0002939 name: regulation of fractalkine biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation." [http://www.copewithcytokines.de] synonym: "regulation of CX3CL1 biosynthesis" EXACT [] synonym: "regulation of CX3CL1 biosynthetic process" EXACT [] synonym: "regulation of fractalkine anabolism" EXACT [] synonym: "regulation of fractalkine biosynthesis" EXACT [] synonym: "regulation of fractalkine formation" EXACT [] synonym: "regulation of fractalkine synthesis" EXACT [] synonym: "regulation of neurotactin biosynthesis" EXACT [] synonym: "regulation of neurotactin biosynthetic process" EXACT [] xref: GO:0050752 is_a: CCO:P0002265 ! regulation of chemokine biosynthetic process [Term] id: CCO:P0002940 name: negative regulation of fractalkine biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation." [http://www.copewithcytokines.de] synonym: "down regulation of fractalkine biosynthetic process" EXACT [] synonym: "down-regulation of fractalkine biosynthetic process" EXACT [] synonym: "downregulation of fractalkine biosynthetic process" EXACT [] synonym: "inhibition of fractalkine biosynthetic process" NARROW [] synonym: "negative regulation of CX3CL1 biosynthesis" EXACT [] synonym: "negative regulation of CX3CL1 biosynthetic process" EXACT [] synonym: "negative regulation of fractalkine anabolism" EXACT [] synonym: "negative regulation of fractalkine biosynthesis" EXACT [] synonym: "negative regulation of fractalkine formation" EXACT [] synonym: "negative regulation of fractalkine synthesis" EXACT [] synonym: "negative regulation of neurotactin biosynthesis" EXACT [] synonym: "negative regulation of neurotactin biosynthetic process" EXACT [] xref: GO:0050753 is_a: CCO:P0002271 ! negative regulation of chemokine biosynthetic process is_a: CCO:P0002939 ! regulation of fractalkine biosynthetic process [Term] id: CCO:P0002941 name: positive regulation of fractalkine biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation." [http://www.copewithcytokines.de] synonym: "activation of fractalkine biosynthetic process" NARROW [] synonym: "positive regulation of CX3CL1 biosynthesis" EXACT [] synonym: "positive regulation of CX3CL1 biosynthetic process" EXACT [] synonym: "positive regulation of fractalkine anabolism" EXACT [] synonym: "positive regulation of fractalkine biosynthesis" EXACT [] synonym: "positive regulation of fractalkine formation" EXACT [] synonym: "positive regulation of fractalkine synthesis" EXACT [] synonym: "positive regulation of neurotactin biosynthesis" EXACT [] synonym: "positive regulation of neurotactin biosynthetic process" EXACT [] synonym: "stimulation of fractalkine biosynthetic process" NARROW [] synonym: "up regulation of fractalkine biosynthetic process" EXACT [] synonym: "up-regulation of fractalkine biosynthetic process" EXACT [] synonym: "upregulation of fractalkine biosynthetic process" EXACT [] xref: GO:0050754 is_a: CCO:P0002272 ! positive regulation of chemokine biosynthetic process is_a: CCO:P0002939 ! regulation of fractalkine biosynthetic process relationship: has_participant CCO:B0055114 ! CAP7_HUMAN relationship: has_participant CCO:B0057234 ! Q86SR2_HUMAN [Term] id: CCO:P0002942 name: regulation of phagocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phagocytosis, the process whereby phagocytes engulf external particulate material." [GOC:ai] xref: GO:0050764 is_a: CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:P0002943 name: negative regulation of phagocytosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "down regulation of phagocytosis" EXACT [] synonym: "down-regulation of phagocytosis" EXACT [] synonym: "downregulation of phagocytosis" EXACT [] synonym: "inhibition of phagocytosis" NARROW [] xref: GO:0050765 is_a: CCO:P0002556 ! negative regulation of endocytosis is_a: CCO:P0002942 ! regulation of phagocytosis relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN [Term] id: CCO:P0002944 name: positive regulation of phagocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phagocytosis." [GOC:ai] synonym: "activation of phagocytosis" NARROW [] synonym: "stimulation of phagocytosis" NARROW [] synonym: "up regulation of phagocytosis" EXACT [] synonym: "up-regulation of phagocytosis" EXACT [] synonym: "upregulation of phagocytosis" EXACT [] xref: GO:0050766 is_a: CCO:P0002557 ! positive regulation of endocytosis is_a: CCO:P0002942 ! regulation of phagocytosis relationship: has_participant CCO:B0036109 ! CO3_HUMAN relationship: has_participant CCO:B0054873 ! FETUA_HUMAN relationship: has_participant CCO:B0055114 ! CAP7_HUMAN relationship: has_participant CCO:B0055165 ! GATA2_HUMAN relationship: has_participant CCO:B0055190 ! PTX3_HUMAN relationship: has_participant CCO:B0055217 ! FCERG_HUMAN relationship: has_participant CCO:B0055282 ! SFTPD_HUMAN relationship: has_participant CCO:B0057234 ! Q86SR2_HUMAN relationship: has_participant CCO:B0057369 ! SACA3_HUMAN [Term] id: CCO:P0002945 name: regulation of neurogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons." [GOC:ai] xref: GO:0050767 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0031654 ! PAX6_HUMAN relationship: has_participant CCO:B0054341 ! WNT7A_HUMAN [Term] id: CCO:P0002946 name: negative regulation of neurogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons." [GOC:ai] synonym: "down regulation of neurogenesis" EXACT [] synonym: "down-regulation of neurogenesis" EXACT [] synonym: "downregulation of neurogenesis" EXACT [] synonym: "inhibition of neurogenesis" NARROW [] xref: GO:0050768 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0002945 ! regulation of neurogenesis relationship: has_participant CCO:B0055185 ! MT3_HUMAN [Term] id: CCO:P0002947 name: positive regulation of neurogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the origin and formation of neurons." [GOC:ai] synonym: "activation of neurogenesis" NARROW [] synonym: "stimulation of neurogenesis" NARROW [] synonym: "up regulation of neurogenesis" EXACT [] synonym: "up-regulation of neurogenesis" EXACT [] synonym: "upregulation of neurogenesis" EXACT [] xref: GO:0050769 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0002945 ! regulation of neurogenesis relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0055315 ! PEDF_HUMAN [Term] id: CCO:P0002948 name: regulation of axonogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." [GOC:ai] xref: GO:0050770 is_a: CCO:P0002945 ! regulation of neurogenesis is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0048655 ! PO3F2_HUMAN relationship: has_participant CCO:B0058808 ! NGL1_HUMAN [Term] id: CCO:P0002949 name: negative regulation of axonogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axonogenesis." [GOC:ai] synonym: "down regulation of axonogenesis" EXACT [] synonym: "down-regulation of axonogenesis" EXACT [] synonym: "downregulation of axonogenesis" EXACT [] synonym: "inhibition of axonogenesis" NARROW [] xref: GO:0050771 is_a: CCO:P0002946 ! negative regulation of neurogenesis is_a: CCO:P0002948 ! regulation of axonogenesis is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0033364 ! RUFY3_HUMAN relationship: has_participant CCO:B0054889 ! THY1_HUMAN relationship: has_participant CCO:B0056401 ! Q59GA0_HUMAN [Term] id: CCO:P0002950 name: positive regulation of axonogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axonogenesis." [GOC:ai] synonym: "activation of axonogenesis" NARROW [] synonym: "stimulation of axonogenesis" NARROW [] synonym: "up regulation of axonogenesis" EXACT [] synonym: "up-regulation of axonogenesis" EXACT [] synonym: "upregulation of axonogenesis" EXACT [] xref: GO:0050772 is_a: CCO:P0002947 ! positive regulation of neurogenesis is_a: CCO:P0002948 ! regulation of axonogenesis is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0027571 ! SLIT2_HUMAN relationship: has_participant CCO:B0054451 ! PLXB1_HUMAN relationship: has_participant CCO:B0057275 ! AMGO1_HUMAN relationship: has_participant CCO:B0058107 ! SEM4D_HUMAN relationship: has_participant CCO:B0058810 ! ROBO2_HUMAN relationship: has_participant CCO:B0059171 ! METRN_HUMAN relationship: has_participant CCO:B0059411 ! ROBO1_HUMAN [Term] id: CCO:P0002951 name: regulation of dendrite development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendrite development." [GOC:ai] xref: GO:0050773 is_a: CCO:P0002945 ! regulation of neurogenesis relationship: has_participant CCO:B0006302 ! DREB_HUMAN [Term] id: CCO:P0002952 name: negative regulation of dendrite morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendrite morphogenesis." [GOC:ai] synonym: "down regulation of dendrite morphogenesis" EXACT [] synonym: "down-regulation of dendrite morphogenesis" EXACT [] synonym: "downregulation of dendrite morphogenesis" EXACT [] synonym: "inhibition of dendrite morphogenesis" NARROW [] xref: GO:0050774 is_a: CCO:P0002900 ! regulation of dendrite morphogenesis is_a: CCO:P0002946 ! negative regulation of neurogenesis is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0005490 ! 1433F_HUMAN relationship: has_participant CCO:B0054519 ! TLX2_HUMAN [Term] id: CCO:P0002953 name: positive regulation of dendrite morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis." [GOC:ai] synonym: "activation of dendrite morphogenesis" NARROW [] synonym: "stimulation of dendrite morphogenesis" NARROW [] synonym: "up regulation of dendrite morphogenesis" EXACT [] synonym: "up-regulation of dendrite morphogenesis" EXACT [] synonym: "upregulation of dendrite morphogenesis" EXACT [] xref: GO:0050775 is_a: CCO:P0002900 ! regulation of dendrite morphogenesis is_a: CCO:P0002947 ! positive regulation of neurogenesis is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis [Term] id: CCO:P0002954 name: RNA destabilization namespace: biological_process def: "Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes." [GOC:ai] subset: gosubset_prok xref: GO:0050779 is_a: CCO:P0002222 ! regulation of RNA stability relationship: has_participant CCO:B0026499 ! TTP_HUMAN [Term] id: CCO:P0002955 name: regulation of cellular process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] subset: gosubset_prok synonym: "regulation of cellular physiological process" EXACT [] xref: GO:0050794 xref: GO:0051244 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0005934 ! WNK4_HUMAN relationship: has_participant CCO:B0058713 ! WNK1_HUMAN relationship: regulates CCO:P0000887 ! cellular process [Term] id: CCO:P0002956 name: regulation of insulin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin." [GOC:ai] xref: GO:0050796 is_a: CCO:P0002744 ! regulation of hormone secretion relationship: has_participant CCO:B0030971 ! IRK11_HUMAN relationship: has_participant CCO:B0050785 ! SSR5_HUMAN relationship: has_participant CCO:B0055450 ! CPT1A_HUMAN relationship: has_participant CCO:B0055598 ! SNP25_HUMAN relationship: has_participant CCO:B0055902 ! PDE3B_HUMAN relationship: has_participant CCO:B0055929 ! NDF1_HUMAN relationship: has_participant CCO:B0056163 ! STX1A_HUMAN [Term] id: CCO:P0002957 name: activated T cell proliferation namespace: biological_process def: "The expansion of a T cell population following activation by an antigenic stimulus." [GOC:add, GOC:dph] comment: Note that this term is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells. synonym: "activated T lymphocyte proliferation" EXACT [] synonym: "activated T-cell proliferation" EXACT [] synonym: "activated T-lymphocyte proliferation" EXACT [] xref: GO:0050798 is_a: CCO:P0002039 ! T cell proliferation [Term] id: CCO:P0002958 name: regulation of synaptic transmission namespace: biological_process def: "Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] xref: GO:0050804 is_a: CCO:P0003172 ! regulation of transmission of nerve impulse relationship: has_participant CCO:B0020611 ! GRIK2_HUMAN relationship: has_participant CCO:B0037398 ! PXK_HUMAN relationship: has_participant CCO:B0055124 ! NTF3_HUMAN [Term] id: CCO:P0002959 name: negative regulation of synaptic transmission namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "down regulation of synaptic transmission" EXACT [] synonym: "down-regulation of synaptic transmission" EXACT [] synonym: "downregulation of synaptic transmission" EXACT [] synonym: "inhibition of synaptic transmission" NARROW [] xref: GO:0050805 is_a: CCO:P0002958 ! regulation of synaptic transmission is_a: CCO:P0003173 ! negative regulation of transmission of nerve impulse [Term] id: CCO:P0002960 name: positive regulation of synaptic transmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "activation of synaptic transmission" NARROW [] synonym: "stimulation of synaptic transmission" NARROW [] synonym: "up regulation of synaptic transmission" EXACT [] synonym: "up-regulation of synaptic transmission" EXACT [] synonym: "upregulation of synaptic transmission" EXACT [] xref: GO:0050806 is_a: CCO:P0002958 ! regulation of synaptic transmission is_a: CCO:P0003174 ! positive regulation of transmission of nerve impulse relationship: has_participant CCO:B0001473 ! TNFB_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0020611 ! GRIK2_HUMAN [Term] id: CCO:P0002961 name: regulation of synapse organization and biogenesis namespace: biological_process def: "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:dph, GOC:tb] synonym: "regulation of synapse structure" EXACT [] xref: GO:0050807 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis relationship: has_participant CCO:B0039858 ! KLK8_HUMAN [Term] id: CCO:P0002962 name: regulation of steroid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:ai] subset: gosubset_prok synonym: "regulation of steroid anabolism" EXACT [] synonym: "regulation of steroid biosynthesis" EXACT [] synonym: "regulation of steroid formation" EXACT [] synonym: "regulation of steroid synthesis" EXACT [] synonym: "regulation of steroidogenesis" EXACT [] xref: GO:0050810 is_a: CCO:P0001141 ! regulation of steroid metabolic process relationship: has_participant CCO:B0055892 ! STF1_HUMAN [Term] id: CCO:P0002963 name: regulation of acyl-CoA biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA." [GOC:ai] subset: gosubset_prok synonym: "regulation of acyl-CoA anabolism" EXACT [] synonym: "regulation of acyl-CoA biosynthesis" EXACT [] synonym: "regulation of acyl-CoA formation" EXACT [] synonym: "regulation of acyl-CoA synthesis" EXACT [] xref: GO:0050812 is_a: CCO:P0002055 ! regulation of fatty acid biosynthetic process is_a: CCO:P0003059 ! regulation of coenzyme metabolic process [Term] id: CCO:P0002964 name: protein stabilization namespace: biological_process def: "Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation." [GOC:ai] subset: gosubset_prok synonym: "lysosomal protein stabilization" NARROW [] synonym: "positive regulation of protein stability" EXACT [] synonym: "protein sequestering" RELATED [] synonym: "protein stabilization activity" RELATED [] xref: GO:0050821 is_a: CCO:P0001482 ! regulation of protein stability relationship: has_participant CCO:B0001366 ! MDM4_HUMAN relationship: has_participant CCO:B0001600 ! VHL_HUMAN relationship: has_participant CCO:B0001832 ! TBRG1_HUMAN relationship: has_participant CCO:B0002116 ! NOG1_HUMAN relationship: has_participant CCO:B0006031 ! PRGC1_HUMAN relationship: has_participant CCO:B0017902 ! RBM38_HUMAN relationship: has_participant CCO:B0026912 ! PEX6_HUMAN relationship: has_participant CCO:B0028600 ! APOA1_HUMAN relationship: has_participant CCO:B0055151 ! CPN2_HUMAN relationship: has_participant CCO:B0055660 ! COG7_HUMAN relationship: has_participant CCO:B0055745 ! KPCD_HUMAN relationship: has_participant CCO:B0055963 ! MORC3_HUMAN relationship: has_participant CCO:B0057301 ! STX12_HUMAN relationship: has_participant CCO:B0058237 ! COG3_HUMAN relationship: has_participant CCO:B0058452 ! SNAG_HUMAN relationship: has_participant CCO:B0058866 ! A1CF_HUMAN relationship: has_participant CCO:B0058867 ! HPS4_HUMAN relationship: has_participant CCO:B0058994 ! AHSP_HUMAN [Term] id: CCO:P0002965 name: progesterone receptor signaling pathway namespace: biological_process def: "Any series of molecular signals generated as a consequence of a progesterone binding to its receptor." [GOC:ai, GOC:mah, PMID:14744870] synonym: "progesterone receptor signalling pathway" EXACT [] xref: GO:0050847 is_a: CCO:P0001278 ! steroid hormone receptor signaling pathway relationship: has_participant CCO:B0054719 ! UBR5_HUMAN relationship: has_participant CCO:B0055949 ! KLF9_HUMAN [Term] id: CCO:P0002966 name: regulation of calcium-mediated signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process by which a cell uses calcium ions to convert an extracellular signal into a response." [GOC:ai] synonym: "regulation of calcium-mediated signalling" EXACT [] xref: GO:0050848 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0056070 ! RGN_HUMAN relationship: regulates CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:P0002967 name: negative regulation of calcium-mediated signaling namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium-mediated signaling." [GOC:ai, PMID:11696592] synonym: "down regulation of calcium-mediated signaling" EXACT [] synonym: "down-regulation of calcium-mediated signaling" EXACT [] synonym: "downregulation of calcium-mediated signaling" EXACT [] synonym: "inhibition of calcium-mediated signaling" NARROW [] synonym: "negative regulation of calcium-mediated signalling" EXACT [] xref: GO:0050849 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002966 ! regulation of calcium-mediated signaling relationship: has_participant CCO:B0022559 ! SLAP2_HUMAN relationship: negatively_regulates CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:P0002968 name: positive regulation of calcium-mediated signaling namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling." [GOC:ai] synonym: "activation of calcium-mediated signaling" NARROW [] synonym: "positive regulation of calcium-mediated signalling" EXACT [] synonym: "stimulation of calcium-mediated signaling" NARROW [] synonym: "up regulation of calcium-mediated signaling" EXACT [] synonym: "up-regulation of calcium-mediated signaling" EXACT [] synonym: "upregulation of calcium-mediated signaling" EXACT [] xref: GO:0050850 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002966 ! regulation of calcium-mediated signaling relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0042830 ! FCERA_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0055534 ! CAD13_HUMAN relationship: has_participant CCO:B0055544 ! P2RX3_HUMAN relationship: has_participant CCO:B0056916 ! TRAT1_HUMAN relationship: has_participant CCO:B0058122 ! P2RX5_HUMAN relationship: has_participant CCO:B0058423 ! P2RX4_HUMAN relationship: has_participant CCO:B0059076 ! P2RX2_HUMAN relationship: positively_regulates CCO:P0001145 ! calcium-mediated signaling [Term] id: CCO:P0002969 name: antigen receptor-mediated signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell." [GOC:add] synonym: "antigen receptor-mediated signalling pathway" EXACT [] xref: GO:0050851 is_a: CCO:P0000547 ! immune response-activating cell surface receptor signaling pathway relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0022559 ! SLAP2_HUMAN relationship: has_participant CCO:B0054343 ! SH2B2_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0058995 ! SPG21_HUMAN [Term] id: CCO:P0002970 name: T cell receptor signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell." [GOC:add] synonym: "T lymphocyte receptor signaling pathway" EXACT [] synonym: "T lymphocyte receptor signalling pathway" EXACT [] synonym: "T-cell receptor signaling pathway" EXACT [] synonym: "T-cell receptor signalling pathway" EXACT [] synonym: "T-lymphocyte receptor signaling pathway" EXACT [] synonym: "T-lymphocyte receptor signalling pathway" EXACT [] synonym: "TCR signaling pathway" EXACT [] xref: GO:0050852 is_a: CCO:P0002969 ! antigen receptor-mediated signaling pathway relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0005524 ! NEMO_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005609 ! FYN_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0054889 ! THY1_HUMAN relationship: has_participant CCO:B0055513 ! CACB3_HUMAN relationship: has_participant CCO:B0056401 ! Q59GA0_HUMAN relationship: has_participant CCO:B0059106 ! MALT1_HUMAN [Term] id: CCO:P0002971 name: B cell receptor signaling pathway namespace: biological_process def: "A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell." [GOC:add] synonym: "B cell receptor signalling pathway" EXACT [] synonym: "B lymphocyte receptor signaling pathway" EXACT [] synonym: "B lymphocyte receptor signalling pathway" EXACT [] synonym: "B-cell receptor signaling pathway" EXACT [] synonym: "B-cell receptor signalling pathway" EXACT [] synonym: "B-lymphocyte receptor signaling pathway" EXACT [] synonym: "B-lymphocyte receptor signalling pathway" EXACT [] xref: GO:0050853 is_a: CCO:P0002969 ! antigen receptor-mediated signaling pathway relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0049019 ! IGHM_HUMAN relationship: has_participant CCO:B0054996 ! CD79A_HUMAN relationship: has_participant CCO:B0055365 ! KSYK_HUMAN relationship: has_participant CCO:B0056892 ! Q6P5Z4_HUMAN relationship: has_participant CCO:B0056928 ! Q6QEF7_HUMAN relationship: has_participant CCO:B0058644 ! NTAL_HUMAN [Term] id: CCO:P0002972 name: regulation of antigen receptor-mediated signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell." [GOC:ai] synonym: "regulation of antigen receptor mediated signalling pathway" EXACT [] xref: GO:0050854 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0002969 ! antigen receptor-mediated signaling pathway [Term] id: CCO:P0002973 name: regulation of B cell receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell." [GOC:ai] synonym: "regulation of B cell receptor signalling pathway" EXACT [] synonym: "regulation of B lymphocyte receptor signaling pathway" EXACT [] synonym: "regulation of B lymphocyte receptor signalling pathway" EXACT [] synonym: "regulation of B-cell receptor signaling pathway" EXACT [] synonym: "regulation of B-cell receptor signalling pathway" EXACT [] synonym: "regulation of B-lymphocyte receptor signaling pathway" EXACT [] synonym: "regulation of B-lymphocyte receptor signalling pathway" EXACT [] xref: GO:0050855 is_a: CCO:P0002972 ! regulation of antigen receptor-mediated signaling pathway relationship: regulates CCO:P0002971 ! B cell receptor signaling pathway [Term] id: CCO:P0002974 name: regulation of T cell receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell." [GOC:ai] synonym: "regulation of T lymphocyte receptor signaling pathway" EXACT [] synonym: "regulation of T lymphocyte receptor signalling pathway" EXACT [] synonym: "regulation of T-cell receptor signaling pathway" EXACT [] synonym: "regulation of T-cell receptor signalling pathway" EXACT [] synonym: "regulation of T-lymphocyte receptor signaling pathway" EXACT [] synonym: "regulation of T-lymphocyte receptor signalling pathway" EXACT [] synonym: "regulation of TCR signaling pathway" EXACT [] xref: GO:0050856 is_a: CCO:P0002972 ! regulation of antigen receptor-mediated signaling pathway relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: regulates CCO:P0002970 ! T cell receptor signaling pathway [Term] id: CCO:P0002975 name: positive regulation of antigen receptor-mediated signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell." [GOC:ai] synonym: "activation of antigen receptor-mediated signaling pathway" NARROW [] synonym: "positive regulation of antigen receptor mediated signalling pathway" EXACT [] synonym: "stimulation of antigen receptor-mediated signaling pathway" NARROW [] synonym: "up regulation of antigen receptor-mediated signaling pathway" EXACT [] synonym: "up-regulation of antigen receptor-mediated signaling pathway" EXACT [] synonym: "upregulation of antigen receptor-mediated signaling pathway" EXACT [] xref: GO:0050857 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0002972 ! regulation of antigen receptor-mediated signaling pathway relationship: has_participant CCO:B0001499 ! CD45_HUMAN relationship: positively_regulates CCO:P0002969 ! antigen receptor-mediated signaling pathway [Term] id: CCO:P0002976 name: negative regulation of antigen receptor-mediated signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell." [GOC:ai] synonym: "down regulation of antigen receptor-mediated signaling pathway" EXACT [] synonym: "down-regulation of antigen receptor-mediated signaling pathway" EXACT [] synonym: "downregulation of antigen receptor-mediated signaling pathway" EXACT [] synonym: "inhibition of antigen receptor-mediated signaling pathway" NARROW [] synonym: "negative regulation of antigen receptor mediated signalling pathway" EXACT [] xref: GO:0050858 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0002972 ! regulation of antigen receptor-mediated signaling pathway relationship: negatively_regulates CCO:P0002969 ! antigen receptor-mediated signaling pathway [Term] id: CCO:P0002977 name: negative regulation of B cell receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell." [GOC:ai] synonym: "down regulation of B cell receptor signaling pathway" EXACT [] synonym: "down-regulation of B cell receptor signaling pathway" EXACT [] synonym: "downregulation of B cell receptor signaling pathway" EXACT [] synonym: "inhibition of B cell receptor signaling pathway" NARROW [] synonym: "negative regulation of B cell receptor signalling pathway" EXACT [] synonym: "negative regulation of B lymphocyte receptor signaling pathway" EXACT [] synonym: "negative regulation of B lymphocyte receptor signalling pathway" EXACT [] synonym: "negative regulation of B-cell receptor signaling pathway" EXACT [] synonym: "negative regulation of B-cell receptor signalling pathway" EXACT [] synonym: "negative regulation of B-lymphocyte receptor signaling pathway" EXACT [] synonym: "negative regulation of B-lymphocyte receptor signalling pathway" EXACT [] xref: GO:0050859 is_a: CCO:P0002973 ! regulation of B cell receptor signaling pathway is_a: CCO:P0002976 ! negative regulation of antigen receptor-mediated signaling pathway relationship: negatively_regulates CCO:P0002971 ! B cell receptor signaling pathway [Term] id: CCO:P0002978 name: negative regulation of T cell receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell." [GOC:ai] synonym: "down regulation of T cell receptor signaling pathway" EXACT [] synonym: "down-regulation of T cell receptor signaling pathway" EXACT [] synonym: "downregulation of T cell receptor signaling pathway" EXACT [] synonym: "inhibition of T cell receptor signaling pathway" NARROW [] synonym: "negative regulation of T cell receptor signalling pathway" EXACT [] synonym: "negative regulation of T lymphocyte receptor signaling pathway" EXACT [] synonym: "negative regulation of T lymphocyte receptor signalling pathway" EXACT [] synonym: "negative regulation of T-cell receptor signaling pathway" EXACT [] synonym: "negative regulation of T-lymphocyte receptor signaling pathway" EXACT [] synonym: "negative regulation of T-lymphocyte receptor signalling pathway" EXACT [] synonym: "negative regulation of TCR signaling pathway" EXACT [] xref: GO:0050860 is_a: CCO:P0002974 ! regulation of T cell receptor signaling pathway is_a: CCO:P0002976 ! negative regulation of antigen receptor-mediated signaling pathway relationship: has_participant CCO:B0006027 ! ELF1_HUMAN relationship: has_participant CCO:B0054889 ! THY1_HUMAN relationship: has_participant CCO:B0056401 ! Q59GA0_HUMAN relationship: negatively_regulates CCO:P0002970 ! T cell receptor signaling pathway [Term] id: CCO:P0002979 name: positive regulation of B cell receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell." [GOC:ai] synonym: "activation of B cell receptor signaling pathway" NARROW [] synonym: "positive regulation of B cell receptor signalling pathway" EXACT [] synonym: "positive regulation of B lymphocyte receptor signaling pathway" EXACT [] synonym: "positive regulation of B lymphocyte receptor signalling pathway" EXACT [] synonym: "positive regulation of B-cell receptor signaling pathway" EXACT [] synonym: "positive regulation of B-cell receptor signalling pathway" EXACT [] synonym: "positive regulation of B-lymphocyte receptor signaling pathway" EXACT [] synonym: "positive regulation of B-lymphocyte receptor signalling pathway" EXACT [] synonym: "stimulation of B cell receptor signaling pathway" NARROW [] synonym: "up regulation of B cell receptor signaling pathway" EXACT [] synonym: "up-regulation of B cell receptor signaling pathway" EXACT [] synonym: "upregulation of B cell receptor signaling pathway" EXACT [] xref: GO:0050861 is_a: CCO:P0002973 ! regulation of B cell receptor signaling pathway is_a: CCO:P0002975 ! positive regulation of antigen receptor-mediated signaling pathway relationship: has_participant CCO:B0057595 ! NFAM1_HUMAN relationship: positively_regulates CCO:P0002971 ! B cell receptor signaling pathway [Term] id: CCO:P0002980 name: positive regulation of T cell receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell." [GOC:ai] synonym: "activation of T cell receptor signaling pathway" NARROW [] synonym: "positive regulation of T cell receptor signalling pathway" EXACT [] synonym: "positive regulation of T lymphocyte receptor signaling pathway" EXACT [] synonym: "positive regulation of T lymphocyte receptor signalling pathway" EXACT [] synonym: "positive regulation of T-cell receptor signaling pathway" EXACT [] synonym: "positive regulation of T-lymphocyte receptor signaling pathway" EXACT [] synonym: "positive regulation of T-lymphocyte receptor signalling pathway" EXACT [] synonym: "positive regulation of TCR signaling pathway" EXACT [] synonym: "stimulation of T cell receptor signaling pathway" NARROW [] synonym: "up regulation of T cell receptor signaling pathway" EXACT [] synonym: "up-regulation of T cell receptor signaling pathway" EXACT [] synonym: "upregulation of T cell receptor signaling pathway" EXACT [] xref: GO:0050862 is_a: CCO:P0002974 ! regulation of T cell receptor signaling pathway is_a: CCO:P0002975 ! positive regulation of antigen receptor-mediated signaling pathway relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0056916 ! TRAT1_HUMAN relationship: positively_regulates CCO:P0002970 ! T cell receptor signaling pathway [Term] id: CCO:P0002981 name: regulation of T cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "regulation of T lymphocyte activation" EXACT [] synonym: "regulation of T-cell activation" EXACT [] synonym: "regulation of T-lymphocyte activation" EXACT [] xref: GO:0050863 is_a: CCO:P0003065 ! regulation of lymphocyte activation relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0054492 ! LAT_HUMAN relationship: has_participant CCO:B0058939 ! PAG1_HUMAN relationship: has_participant CCO:B0059342 ! SIT1_HUMAN [Term] id: CCO:P0002982 name: regulation of B cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of B cell activation." [GOC:ai] synonym: "regulation of B lymphocyte activation" EXACT [] synonym: "regulation of B-cell activation" EXACT [] synonym: "regulation of B-lymphocyte activation" EXACT [] xref: GO:0050864 is_a: CCO:P0003065 ! regulation of lymphocyte activation [Term] id: CCO:P0002983 name: regulation of cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai] xref: GO:0050865 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0002984 name: negative regulation of cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell activation." [GOC:ai] synonym: "down regulation of cell activation" EXACT [] synonym: "down-regulation of cell activation" EXACT [] synonym: "downregulation of cell activation" EXACT [] synonym: "inhibition of cell activation" NARROW [] xref: GO:0050866 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0002983 ! regulation of cell activation [Term] id: CCO:P0002985 name: positive regulation of cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai] synonym: "activation of cell activation" NARROW [] synonym: "stimulation of cell activation" NARROW [] synonym: "up regulation of cell activation" EXACT [] synonym: "up-regulation of cell activation" EXACT [] synonym: "upregulation of cell activation" EXACT [] xref: GO:0050867 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0002983 ! regulation of cell activation [Term] id: CCO:P0002986 name: negative regulation of T cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "down regulation of T cell activation" EXACT [] synonym: "down-regulation of T cell activation" EXACT [] synonym: "downregulation of T cell activation" EXACT [] synonym: "inhibition of T cell activation" NARROW [] synonym: "negative regulation of T lymphocyte activation" EXACT [] synonym: "negative regulation of T-cell activation" EXACT [] synonym: "negative regulation of T-lymphocyte activation" EXACT [] xref: GO:0050868 is_a: CCO:P0002981 ! regulation of T cell activation is_a: CCO:P0003066 ! negative regulation of lymphocyte activation relationship: has_participant CCO:B0055103 ! LAG3_HUMAN relationship: has_participant CCO:B0057364 ! LAX1_HUMAN relationship: has_participant CCO:B0058939 ! PAG1_HUMAN [Term] id: CCO:P0002987 name: negative regulation of B cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of B cell activation." [GOC:ai] synonym: "down regulation of B cell activation" EXACT [] synonym: "down-regulation of B cell activation" EXACT [] synonym: "downregulation of B cell activation" EXACT [] synonym: "inhibition of B cell activation" NARROW [] synonym: "negative regulation of B lymphocyte activation" EXACT [] synonym: "negative regulation of B-cell activation" EXACT [] synonym: "negative regulation of B-lymphocyte activation" EXACT [] xref: GO:0050869 is_a: CCO:P0002982 ! regulation of B cell activation is_a: CCO:P0003066 ! negative regulation of lymphocyte activation relationship: has_participant CCO:B0022559 ! SLAP2_HUMAN relationship: has_participant CCO:B0039142 ! FOXJ1_HUMAN [Term] id: CCO:P0002988 name: positive regulation of T cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "activation of T cell activation" NARROW [] synonym: "positive regulation of T lymphocyte activation" EXACT [] synonym: "positive regulation of T-cell activation" EXACT [] synonym: "positive regulation of T-lymphocyte activation" EXACT [] synonym: "stimulation of T cell activation" NARROW [] synonym: "up regulation of T cell activation" EXACT [] synonym: "up-regulation of T cell activation" EXACT [] synonym: "upregulation of T cell activation" EXACT [] xref: GO:0050870 is_a: CCO:P0002981 ! regulation of T cell activation is_a: CCO:P0003067 ! positive regulation of lymphocyte activation relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001490 ! LCK_HUMAN relationship: has_participant CCO:B0005170 ! TRAF2_HUMAN relationship: has_participant CCO:B0005536 ! TRAF6_HUMAN relationship: has_participant CCO:B0005740 ! CD4_HUMAN relationship: has_participant CCO:B0038746 ! M3K7_HUMAN relationship: has_participant CCO:B0054889 ! THY1_HUMAN relationship: has_participant CCO:B0055793 ! CD47_HUMAN relationship: has_participant CCO:B0056401 ! Q59GA0_HUMAN relationship: has_participant CCO:B0059045 ! SIRPG_HUMAN relationship: has_participant CCO:B0059106 ! MALT1_HUMAN [Term] id: CCO:P0002989 name: positive regulation of B cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of B cell activation." [GOC:ai] synonym: "activation of B cell activation" NARROW [] synonym: "positive regulation of B lymphocyte activation" EXACT [] synonym: "positive regulation of B-cell activation" EXACT [] synonym: "positive regulation of B-lymphocyte activation" EXACT [] synonym: "stimulation of B cell activation" NARROW [] synonym: "up regulation of B cell activation" EXACT [] synonym: "up-regulation of B cell activation" EXACT [] synonym: "upregulation of B cell activation" EXACT [] xref: GO:0050871 is_a: CCO:P0002982 ! regulation of B cell activation is_a: CCO:P0003067 ! positive regulation of lymphocyte activation [Term] id: CCO:P0002990 name: regulation of pigment cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." [GOC:ai] xref: GO:0050932 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0002991 name: regulation of iridophore differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of iridophore differentiation." [GOC:ai] xref: GO:0050937 is_a: CCO:P0002990 ! regulation of pigment cell differentiation [Term] id: CCO:P0002992 name: regulation of xanthophore differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of xanthophore differentiation." [GOC:ai] comment: Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure. xref: GO:0050938 is_a: CCO:P0002990 ! regulation of pigment cell differentiation [Term] id: CCO:P0002993 name: regulation of early stripe melanocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation." [GOC:ai] synonym: "regulation of early stripe melanophore differentiation" EXACT [] xref: GO:0050939 is_a: CCO:P0002448 ! regulation of melanocyte differentiation [Term] id: CCO:P0002994 name: regulation of late stripe melanocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation." [GOC:ai] synonym: "regulation of late stripe melanophore differentiation" EXACT [] xref: GO:0050940 is_a: CCO:P0002448 ! regulation of melanocyte differentiation [Term] id: CCO:P0002995 name: negative regulation of pigment cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "down regulation of pigment cell differentiation" EXACT [] synonym: "down-regulation of pigment cell differentiation" EXACT [] synonym: "downregulation of pigment cell differentiation" EXACT [] synonym: "inhibition of pigment cell differentiation" NARROW [] xref: GO:0050941 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0002990 ! regulation of pigment cell differentiation [Term] id: CCO:P0002996 name: positive regulation of pigment cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "activation of pigment cell differentiation" NARROW [] synonym: "stimulation of pigment cell differentiation" NARROW [] synonym: "up regulation of pigment cell differentiation" EXACT [] synonym: "up-regulation of pigment cell differentiation" EXACT [] synonym: "upregulation of pigment cell differentiation" EXACT [] xref: GO:0050942 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0002990 ! regulation of pigment cell differentiation [Term] id: CCO:P0002997 name: negative regulation of iridophore differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of iridophore differentiation." [GOC:ai] synonym: "down regulation of iridophore differentiation" EXACT [] synonym: "down-regulation of iridophore differentiation" EXACT [] synonym: "downregulation of iridophore differentiation" EXACT [] synonym: "inhibition of iridophore differentiation" NARROW [] xref: GO:0050943 is_a: CCO:P0002991 ! regulation of iridophore differentiation is_a: CCO:P0002995 ! negative regulation of pigment cell differentiation [Term] id: CCO:P0002998 name: negative regulation of xanthophore differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of xanthophore differentiation." [GOC:ai] comment: Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure. synonym: "down regulation of xanthophore differentiation" EXACT [] synonym: "down-regulation of xanthophore differentiation" EXACT [] synonym: "downregulation of xanthophore differentiation" EXACT [] synonym: "inhibition of xanthophore differentiation" NARROW [] xref: GO:0050944 is_a: CCO:P0002992 ! regulation of xanthophore differentiation is_a: CCO:P0002995 ! negative regulation of pigment cell differentiation [Term] id: CCO:P0002999 name: positive regulation of iridophore differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of iridophore differentiation." [GOC:ai] synonym: "activation of iridophore differentiation" NARROW [] synonym: "stimulation of iridophore differentiation" NARROW [] synonym: "up regulation of iridophore differentiation" EXACT [] synonym: "up-regulation of iridophore differentiation" EXACT [] synonym: "upregulation of iridophore differentiation" EXACT [] xref: GO:0050945 is_a: CCO:P0002991 ! regulation of iridophore differentiation is_a: CCO:P0002996 ! positive regulation of pigment cell differentiation [Term] id: CCO:P0003000 name: positive regulation of xanthophore differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of xanthophore differentiation." [GOC:ai] comment: Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure. synonym: "activation of xanthophore differentiation" NARROW [] synonym: "stimulation of xanthophore differentiation" NARROW [] synonym: "up regulation of xanthophore differentiation" EXACT [] synonym: "up-regulation of xanthophore differentiation" EXACT [] synonym: "upregulation of xanthophore differentiation" EXACT [] xref: GO:0050946 is_a: CCO:P0002992 ! regulation of xanthophore differentiation is_a: CCO:P0002996 ! positive regulation of pigment cell differentiation [Term] id: CCO:P0003001 name: negative regulation of early stripe melanocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of early stripe melanocyte differentiation." [GOC:ai] synonym: "down regulation of early stripe melanocyte differentiation" EXACT [] synonym: "down-regulation of early stripe melanocyte differentiation" EXACT [] synonym: "downregulation of early stripe melanocyte differentiation" EXACT [] synonym: "inhibition of early stripe melanocyte differentiation" NARROW [] synonym: "negative regulation of early stripe melanophore differentiation" EXACT [] xref: GO:0050947 is_a: CCO:P0002449 ! negative regulation of melanocyte differentiation is_a: CCO:P0002993 ! regulation of early stripe melanocyte differentiation [Term] id: CCO:P0003002 name: positive regulation of early stripe melanocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation." [GOC:ai] synonym: "activation of early stripe melanocyte differentiation" NARROW [] synonym: "positive regulation of early stripe melanophore differentiation" EXACT [] synonym: "stimulation of early stripe melanocyte differentiation" NARROW [] synonym: "up regulation of early stripe melanocyte differentiation" EXACT [] synonym: "up-regulation of early stripe melanocyte differentiation" EXACT [] synonym: "upregulation of early stripe melanocyte differentiation" EXACT [] xref: GO:0050948 is_a: CCO:P0002450 ! positive regulation of melanocyte differentiation is_a: CCO:P0002993 ! regulation of early stripe melanocyte differentiation [Term] id: CCO:P0003003 name: negative regulation of late stripe melanocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of late stripe melanocyte differentiation." [GOC:ai] synonym: "down regulation of late stripe melanocyte differentiation" EXACT [] synonym: "down-regulation of late stripe melanocyte differentiation" EXACT [] synonym: "downregulation of late stripe melanocyte differentiation" EXACT [] synonym: "inhibition of late stripe melanocyte differentiation" NARROW [] synonym: "negative regulation of late stripe melanophore differentiation" EXACT [] xref: GO:0050949 is_a: CCO:P0002449 ! negative regulation of melanocyte differentiation is_a: CCO:P0002994 ! regulation of late stripe melanocyte differentiation [Term] id: CCO:P0003004 name: positive regulation of late stripe melanocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation." [GOC:ai] synonym: "activation of late stripe melanocyte differentiation" NARROW [] synonym: "positive regulation of late stripe melanophore differentiation" EXACT [] synonym: "stimulation of late stripe melanocyte differentiation" NARROW [] synonym: "up regulation of late stripe melanocyte differentiation" EXACT [] synonym: "up-regulation of late stripe melanocyte differentiation" EXACT [] synonym: "upregulation of late stripe melanocyte differentiation" EXACT [] xref: GO:0050950 is_a: CCO:P0002450 ! positive regulation of melanocyte differentiation is_a: CCO:P0002994 ! regulation of late stripe melanocyte differentiation [Term] id: CCO:P0003005 name: barbed-end actin filament capping namespace: biological_process def: "The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X] synonym: "barbed-end actin capping activity" EXACT [] synonym: "barbed-end F-actin capping activity" EXACT [] synonym: "plus-end actin filament capping activity" EXACT [] synonym: "plus-end F-actin capping activity" EXACT [] xref: GO:0051016 is_a: CCO:P0003139 ! actin filament capping relationship: has_participant CCO:B0005582 ! CAZA2_HUMAN relationship: has_participant CCO:B0005604 ! SPTB2_HUMAN relationship: has_participant CCO:B0006125 ! CAPZB_HUMAN relationship: has_participant CCO:B0037556 ! CAZA3_HUMAN relationship: has_participant CCO:B0037567 ! CAZA1_HUMAN relationship: has_participant CCO:B0051606 ! VILL_HUMAN relationship: has_participant CCO:B0051611 ! GELS_HUMAN relationship: has_participant CCO:B0051612 ! AVIL_HUMAN relationship: has_participant CCO:B0051613 ! VILI_HUMAN relationship: has_participant CCO:B0051620 ! ADSV_HUMAN relationship: has_participant CCO:B0054399 ! SPTN2_HUMAN relationship: has_participant CCO:B0054762 ! SVIL_HUMAN relationship: has_participant CCO:B0054990 ! SPTB1_HUMAN relationship: has_participant CCO:B0055324 ! CAPG_HUMAN relationship: has_participant CCO:B0055791 ! DEMA_HUMAN relationship: has_participant CCO:B0055944 ! SPTA2_HUMAN relationship: has_participant CCO:B0058677 ! SPTN4_HUMAN relationship: has_participant CCO:B0058684 ! TARA_HUMAN relationship: has_participant CCO:B0058894 ! SPTN5_HUMAN [Term] id: CCO:P0003006 name: regulation of transcription, meiotic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transcription during meiosis." [GOC:go_curators] synonym: "meiotic regulation of transcription" EXACT [] xref: GO:0051037 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:P0003007 name: negative regulation of transcription, meiotic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transcription during meiosis." [GOC:ai] synonym: "down regulation of transcription, meiotic" EXACT [] synonym: "down-regulation of transcription, meiotic" EXACT [] synonym: "downregulation of transcription, meiotic" EXACT [] synonym: "inhibition of transcription, meiotic" NARROW [] synonym: "meiotic repression of transcription" EXACT [] synonym: "negative regulation of meiotic transcription" EXACT [] xref: GO:0051038 is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent is_a: CCO:P0003006 ! regulation of transcription, meiotic [Term] id: CCO:P0003008 name: positive regulation of transcription, meiotic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transcription during meiosis." [GOC:ai] synonym: "activation of transcription, meiotic" NARROW [] synonym: "positive regulation of meiotic transcription" EXACT [] synonym: "stimulation of transcription, meiotic" NARROW [] synonym: "up regulation of transcription, meiotic" EXACT [] synonym: "up-regulation of transcription, meiotic" EXACT [] synonym: "upregulation of transcription, meiotic" EXACT [] xref: GO:0051039 is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent is_a: CCO:P0003006 ! regulation of transcription, meiotic [Term] id: CCO:P0003009 name: regulation of calcium-independent cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction." [GOC:ai] xref: GO:0051040 is_a: CCO:P0001237 ! regulation of cell-cell adhesion [Term] id: CCO:P0003010 name: positive regulation of calcium-independent cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion." [GOC:ai] synonym: "activation of calcium-independent cell-cell adhesion" NARROW [] synonym: "stimulation of calcium-independent cell-cell adhesion" NARROW [] synonym: "up regulation of calcium-independent cell-cell adhesion" EXACT [] synonym: "up-regulation of calcium-independent cell-cell adhesion" EXACT [] synonym: "upregulation of calcium-independent cell-cell adhesion" EXACT [] xref: GO:0051041 is_a: CCO:P0001239 ! positive regulation of cell-cell adhesion is_a: CCO:P0003009 ! regulation of calcium-independent cell-cell adhesion relationship: has_participant CCO:B0055645 ! X3CL1_HUMAN [Term] id: CCO:P0003011 name: negative regulation of calcium-independent cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion." [GOC:ai] synonym: "down regulation of calcium-independent cell-cell adhesion" EXACT [] synonym: "down-regulation of calcium-independent cell-cell adhesion" EXACT [] synonym: "downregulation of calcium-independent cell-cell adhesion" EXACT [] synonym: "inhibition of calcium-independent cell-cell adhesion" NARROW [] xref: GO:0051042 is_a: CCO:P0001238 ! negative regulation of cell-cell adhesion is_a: CCO:P0003009 ! regulation of calcium-independent cell-cell adhesion [Term] id: CCO:P0003012 name: regulation of membrane protein ectodomain proteolysis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain)." [GOC:ai] subset: gosubset_prok xref: GO:0051043 is_a: CCO:P0001246 ! regulation of proteolysis [Term] id: CCO:P0003013 name: positive regulation of membrane protein ectodomain proteolysis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis." [GOC:ai] subset: gosubset_prok synonym: "activation of membrane protein ectodomain proteolysis" NARROW [] synonym: "stimulation of membrane protein ectodomain proteolysis" NARROW [] synonym: "up regulation of membrane protein ectodomain proteolysis" EXACT [] synonym: "up-regulation of membrane protein ectodomain proteolysis" EXACT [] synonym: "upregulation of membrane protein ectodomain proteolysis" EXACT [] xref: GO:0051044 is_a: CCO:P0002579 ! positive regulation of proteolysis is_a: CCO:P0003012 ! regulation of membrane protein ectodomain proteolysis relationship: has_participant CCO:B0054862 ! APOE_HUMAN [Term] id: CCO:P0003014 name: negative regulation of membrane protein ectodomain proteolysis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis." [GOC:ai] subset: gosubset_prok synonym: "down regulation of membrane protein ectodomain proteolysis" EXACT [] synonym: "down-regulation of membrane protein ectodomain proteolysis" EXACT [] synonym: "downregulation of membrane protein ectodomain proteolysis" EXACT [] synonym: "inhibition of membrane protein ectodomain proteolysis" NARROW [] xref: GO:0051045 is_a: CCO:P0002578 ! negative regulation of proteolysis is_a: CCO:P0003012 ! regulation of membrane protein ectodomain proteolysis relationship: has_participant CCO:B0054831 ! TIMP1_HUMAN [Term] id: CCO:P0003015 name: regulation of DNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] subset: gosubset_prok synonym: "regulation of DNA metabolism" EXACT [] xref: GO:0051052 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [Term] id: CCO:P0003016 name: negative regulation of DNA metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] subset: gosubset_prok synonym: "down regulation of DNA metabolic process" EXACT [] synonym: "down-regulation of DNA metabolic process" EXACT [] synonym: "downregulation of DNA metabolic process" EXACT [] synonym: "inhibition of DNA metabolic process" NARROW [] synonym: "negative regulation of DNA metabolism" EXACT [] xref: GO:0051053 is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0003015 ! regulation of DNA metabolic process [Term] id: CCO:P0003017 name: positive regulation of DNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] subset: gosubset_prok synonym: "activation of DNA metabolic process" NARROW [] synonym: "positive regulation of DNA metabolism" EXACT [] synonym: "stimulation of DNA metabolic process" NARROW [] synonym: "up regulation of DNA metabolic process" EXACT [] synonym: "up-regulation of DNA metabolic process" EXACT [] synonym: "upregulation of DNA metabolic process" EXACT [] xref: GO:0051054 is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0003015 ! regulation of DNA metabolic process [Term] id: CCO:P0003018 name: regulation of small GTPase mediated signal transduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction." [GOC:go_curators] xref: GO:0051056 is_a: CCO:P0000884 ! regulation of signal transduction relationship: has_participant CCO:B0001542 ! NF1_HUMAN relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0001899 ! DAB2P_HUMAN relationship: has_participant CCO:B0002039 ! SIPA1_HUMAN relationship: has_participant CCO:B0005383 ! SOS1_HUMAN relationship: has_participant CCO:B0005550 ! RGL1_HUMAN relationship: has_participant CCO:B0005666 ! SOS2_HUMAN relationship: has_participant CCO:B0005912 ! GNDS_HUMAN relationship: has_participant CCO:B0005995 ! RASA1_HUMAN relationship: has_participant CCO:B0016356 ! Q6KH11_HUMAN relationship: has_participant CCO:B0016357 ! Q6PCE1_HUMAN relationship: has_participant CCO:B0016367 ! RGL3_HUMAN relationship: has_participant CCO:B0016369 ! Q6ZSD5_HUMAN relationship: has_participant CCO:B0018386 ! IQGA1_HUMAN relationship: has_participant CCO:B0018391 ! IQGA2_HUMAN relationship: has_participant CCO:B0018395 ! IQGA3_HUMAN relationship: has_participant CCO:B0019340 ! SYGP1_HUMAN relationship: has_participant CCO:B0019350 ! NGAP_HUMAN relationship: has_participant CCO:B0022152 ! Q4LE71_HUMAN relationship: has_participant CCO:B0023489 ! SI1L2_HUMAN relationship: has_participant CCO:B0023961 ! Q8NIA3_HUMAN relationship: has_participant CCO:B0025120 ! Q59FX3_HUMAN relationship: has_participant CCO:B0027846 ! A8K4V1_HUMAN relationship: has_participant CCO:B0038385 ! RPGF1_HUMAN relationship: has_participant CCO:B0038391 ! Q8IV73_HUMAN relationship: has_participant CCO:B0051400 ! YS018_HUMAN relationship: has_participant CCO:B0051401 ! B1AKC7_HUMAN relationship: has_participant CCO:B0053716 ! A2A2E9_HUMAN relationship: has_participant CCO:B0053747 ! A3KN82_HUMAN relationship: has_participant CCO:B0053846 ! A6NHE2_HUMAN relationship: has_participant CCO:B0053859 ! A6NIB0_HUMAN relationship: has_participant CCO:B0053867 ! A6NJ28_HUMAN relationship: has_participant CCO:B0053977 ! A8K7K1_HUMAN relationship: has_participant CCO:B0053988 ! A8MPS8_HUMAN relationship: has_participant CCO:B0053993 ! A8MQ07_HUMAN relationship: has_participant CCO:B0054007 ! A8MSJ7_HUMAN relationship: has_participant CCO:B0054009 ! A8MSM5_HUMAN relationship: has_participant CCO:B0054179 ! B0QZ65_HUMAN relationship: has_participant CCO:B0054180 ! B0QZ66_HUMAN relationship: has_participant CCO:B0054181 ! B0QZ67_HUMAN relationship: has_participant CCO:B0054381 ! RGRF2_HUMAN relationship: has_participant CCO:B0054416 ! RGL2_HUMAN relationship: has_participant CCO:B0054452 ! SI1L1_HUMAN relationship: has_participant CCO:B0054478 ! RASL2_HUMAN relationship: has_participant CCO:B0054542 ! SI1L3_HUMAN relationship: has_participant CCO:B0054600 ! O75062_HUMAN relationship: has_participant CCO:B0054743 ! GRP1_HUMAN relationship: has_participant CCO:B0054747 ! RASL1_HUMAN relationship: has_participant CCO:B0054757 ! RPGF3_HUMAN relationship: has_participant CCO:B0055384 ! RPGP1_HUMAN relationship: has_participant CCO:B0055804 ! DMPK_HUMAN relationship: has_participant CCO:B0055822 ! RGF1B_HUMAN relationship: has_participant CCO:B0055954 ! RGRF1_HUMAN relationship: has_participant CCO:B0056008 ! RASA3_HUMAN relationship: has_participant CCO:B0056032 ! GAPD1_HUMAN relationship: has_participant CCO:B0056052 ! RASA2_HUMAN relationship: has_participant CCO:B0056222 ! AS250_HUMAN relationship: has_participant CCO:B0056306 ! Q49AP2_HUMAN relationship: has_participant CCO:B0056314 ! Q4G0R5_HUMAN relationship: has_participant CCO:B0056372 ! Q569L6_HUMAN relationship: has_participant CCO:B0056475 ! Q5JS19_HUMAN relationship: has_participant CCO:B0056570 ! Q5T3S6_HUMAN relationship: has_participant CCO:B0056572 ! Q5T3S9_HUMAN relationship: has_participant CCO:B0056646 ! MRCKA_HUMAN relationship: has_participant CCO:B0056661 ! GARL3_HUMAN relationship: has_participant CCO:B0056697 ! RPGP2_HUMAN relationship: has_participant CCO:B0056729 ! MRCKG_HUMAN relationship: has_participant CCO:B0056736 ! GRIPE_HUMAN relationship: has_participant CCO:B0057109 ! VKIND_HUMAN relationship: has_participant CCO:B0057123 ! GRP2_HUMAN relationship: has_participant CCO:B0057283 ! K1219_HUMAN relationship: has_participant CCO:B0057328 ! Q8IUU5_HUMAN relationship: has_participant CCO:B0057331 ! Q8IUY2_HUMAN relationship: has_participant CCO:B0057337 ! GRP3_HUMAN relationship: has_participant CCO:B0057460 ! RGF1C_HUMAN relationship: has_participant CCO:B0057461 ! Q8N437_HUMAN relationship: has_participant CCO:B0057535 ! RGF1A_HUMAN relationship: has_participant CCO:B0057927 ! GRP4_HUMAN relationship: has_participant CCO:B0057952 ! Q8TEA3_HUMAN relationship: has_participant CCO:B0057956 ! RPGF6_HUMAN relationship: has_participant CCO:B0058055 ! RPGF4_HUMAN relationship: has_participant CCO:B0058064 ! RPGF5_HUMAN relationship: has_participant CCO:B0059149 ! Q9UHV4_HUMAN relationship: has_participant CCO:B0059346 ! Q9Y408_HUMAN relationship: has_participant CCO:B0059362 ! RPGF2_HUMAN relationship: has_participant CCO:B0059385 ! MRCKB_HUMAN relationship: regulates CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:P0003019 name: positive regulation of small GTPase mediated signal transduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction." [GOC:ai] synonym: "activation of small GTPase mediated signal transduction" NARROW [] synonym: "stimulation of small GTPase mediated signal transduction" NARROW [] synonym: "up regulation of small GTPase mediated signal transduction" EXACT [] synonym: "up-regulation of small GTPase mediated signal transduction" EXACT [] synonym: "upregulation of small GTPase mediated signal transduction" EXACT [] xref: GO:0051057 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: has_participant CCO:B0055647 ! RELN_HUMAN relationship: positively_regulates CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:P0003020 name: negative regulation of small GTPase mediated signal transduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase mediated signal transduction." [GOC:ai] synonym: "down regulation of small GTPase mediated signal transduction" EXACT [] synonym: "down-regulation of small GTPase mediated signal transduction" EXACT [] synonym: "downregulation of small GTPase mediated signal transduction" EXACT [] synonym: "inhibition of small GTPase mediated signal transduction" NARROW [] xref: GO:0051058 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0003018 ! regulation of small GTPase mediated signal transduction relationship: negatively_regulates CCO:P0000781 ! small GTPase mediated signal transduction [Term] id: CCO:P0003021 name: regulation of transcription factor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] subset: gosubset_prok xref: GO:0051090 is_a: CCO:P0002369 ! regulation of transcription relationship: has_participant CCO:B0005375 ! STK36_HUMAN relationship: has_participant CCO:B0023496 ! A4D2B3_HUMAN relationship: has_participant CCO:B0023501 ! TAF6L_HUMAN relationship: has_participant CCO:B0053756 ! A4D299_HUMAN relationship: has_participant CCO:B0054947 ! HMOX1_HUMAN relationship: has_participant CCO:B0055440 ! TAF6_HUMAN relationship: has_participant CCO:B0057428 ! S6OS1_HUMAN [Term] id: CCO:P0003022 name: positive regulation of transcription factor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] subset: gosubset_prok synonym: "activation of transcription factor activity" NARROW [] synonym: "stimulation of transcription factor activity" NARROW [] synonym: "up regulation of transcription factor activity" EXACT [] synonym: "up-regulation of transcription factor activity" EXACT [] synonym: "upregulation of transcription factor activity" EXACT [] xref: GO:0051091 is_a: CCO:P0003021 ! regulation of transcription factor activity relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001476 ! IL1B_HUMAN relationship: has_participant CCO:B0001728 ! EP300_HUMAN relationship: has_participant CCO:B0005324 ! CEBPG_HUMAN relationship: has_participant CCO:B0040022 ! JMY_HUMAN relationship: has_participant CCO:B0057419 ! ABRA_HUMAN relationship: has_participant CCO:B0057595 ! NFAM1_HUMAN [Term] id: CCO:P0003023 name: positive regulation of NF-kappaB transcription factor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB." [GOC:dph, GOC:tb, PMID:15087454, PMID:15170030] synonym: "activation of NF-kappaB" EXACT [] synonym: "activation of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb] synonym: "NF-kappaB activation" EXACT [] xref: GO:0051092 is_a: CCO:P0003022 ! positive regulation of transcription factor activity relationship: has_participant CCO:B0001458 ! BCL10_HUMAN relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN relationship: has_participant CCO:B0001474 ! TNFA_HUMAN relationship: has_participant CCO:B0001495 ! NPM_HUMAN relationship: has_participant CCO:B0001752 ! UB2V1_HUMAN relationship: has_participant CCO:B0002228 ! ASC_HUMAN relationship: has_participant CCO:B0005216 ! RIPK2_HUMAN relationship: has_participant CCO:B0005522 ! IKKB_HUMAN relationship: has_participant CCO:B0005865 ! TF65_HUMAN relationship: has_participant CCO:B0005869 ! UBE2N_HUMAN relationship: has_participant CCO:B0016569 ! KCC2A_HUMAN relationship: has_participant CCO:B0018761 ! M3K13_HUMAN relationship: has_participant CCO:B0025051 ! Q5JUN8_HUMAN relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0054438 ! TLR3_HUMAN relationship: has_participant CCO:B0054883 ! PA21B_HUMAN relationship: has_participant CCO:B0055216 ! PRDX3_HUMAN relationship: has_participant CCO:B0056670 ! Q5VYX9_HUMAN relationship: has_participant CCO:B0056671 ! Q5VYY0_HUMAN relationship: has_participant CCO:B0057124 ! NLRC3_HUMAN relationship: has_participant CCO:B0057322 ! RB6I2_HUMAN relationship: has_participant CCO:B0058102 ! EDA_HUMAN relationship: has_participant CCO:B0058458 ! MYD88_HUMAN relationship: has_participant CCO:B0058559 ! CAR11_HUMAN relationship: has_participant CCO:B0058770 ! TNR27_HUMAN relationship: has_participant CCO:B0058795 ! NOD2_HUMAN [Term] id: CCO:P0003024 name: DNA ligation during DNA-dependent DNA replication namespace: biological_process def: "The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, as occurs during DNA-dependent DNA replication." [GOC:ai] subset: gosubset_prok xref: GO:0051104 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000629 ! DNA-dependent DNA replication [Term] id: CCO:P0003025 name: regulation of DNA ligation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase." [GOC:ai] subset: gosubset_prok xref: GO:0051105 is_a: CCO:P0003015 ! regulation of DNA metabolic process [Term] id: CCO:P0003026 name: positive regulation of DNA ligation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase." [GOC:ai] subset: gosubset_prok synonym: "activation of DNA ligation" NARROW [] synonym: "stimulation of DNA ligation" NARROW [] synonym: "up regulation of DNA ligation" EXACT [] synonym: "up-regulation of DNA ligation" EXACT [] synonym: "upregulation of DNA ligation" EXACT [] xref: GO:0051106 is_a: CCO:P0003017 ! positive regulation of DNA metabolic process is_a: CCO:P0003025 ! regulation of DNA ligation relationship: has_participant CCO:B0001721 ! RAD51_HUMAN [Term] id: CCO:P0003027 name: negative regulation of DNA ligation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase." [GOC:ai] subset: gosubset_prok synonym: "down regulation of DNA ligation" EXACT [] synonym: "down-regulation of DNA ligation" EXACT [] synonym: "downregulation of DNA ligation" EXACT [] synonym: "inhibition of DNA ligation" NARROW [] xref: GO:0051107 is_a: CCO:P0003016 ! negative regulation of DNA metabolic process is_a: CCO:P0003025 ! regulation of DNA ligation [Term] id: CCO:P0003028 name: transcriptional preinitiation complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from the RNA polymerase II promoter." [PMID:10882737] synonym: "transcription PIC biosynthesis" EXACT [] synonym: "transcription PIC formation" EXACT [] synonym: "transcriptional preinitiation complex formation" EXACT [] xref: GO:0051123 is_a: CCO:P0000657 ! regulation of transcription from RNA polymerase II promoter [Term] id: CCO:P0003029 name: regulation of actin nucleation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament." [GOC:ai] xref: GO:0051125 is_a: CCO:P0001736 ! regulation of actin cytoskeleton organization and biogenesis [Term] id: CCO:P0003030 name: negative regulation of actin nucleation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament." [GOC:ai] synonym: "down regulation of actin nucleation" EXACT [] synonym: "down-regulation of actin nucleation" EXACT [] synonym: "downregulation of actin nucleation" EXACT [] synonym: "inhibition of actin nucleation" NARROW [] xref: GO:0051126 is_a: CCO:P0003029 ! regulation of actin nucleation is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis relationship: has_participant CCO:B0001581 ! COR1A_HUMAN [Term] id: CCO:P0003031 name: positive regulation of actin nucleation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament." [GOC:ai] synonym: "activation of actin nucleation" NARROW [] synonym: "stimulation of actin nucleation" NARROW [] synonym: "up regulation of actin nucleation" EXACT [] synonym: "up-regulation of actin nucleation" EXACT [] synonym: "upregulation of actin nucleation" EXACT [] xref: GO:0051127 is_a: CCO:P0003029 ! regulation of actin nucleation is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0003032 name: regulation of cellular component organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] subset: gosubset_prok synonym: "regulation of cell organisation and biogenesis" EXACT [] synonym: "regulation of cell organization and biogenesis" EXACT [] synonym: "regulation of cellular component organisation and biogenesis" EXACT [] xref: GO:0051128 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0015573 ! ST38L_HUMAN [Term] id: CCO:P0003033 name: negative regulation of cellular component organization and biogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] subset: gosubset_prok synonym: "down regulation of cell organization and biogenesis" EXACT [] synonym: "down-regulation of cell organization and biogenesis" EXACT [] synonym: "downregulation of cell organization and biogenesis" EXACT [] synonym: "inhibition of cell organization and biogenesis" NARROW [] synonym: "negative regulation of cell organisation and biogenesis" EXACT [] xref: GO:0051129 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0003034 name: positive regulation of cellular component organization and biogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "activation of cell organization and biogenesis" NARROW [] synonym: "positive regulation of cell organisation and biogenesis" EXACT [] synonym: "stimulation of cell organization and biogenesis" NARROW [] synonym: "up regulation of cell organization and biogenesis" EXACT [] synonym: "up-regulation of cell organization and biogenesis" EXACT [] synonym: "upregulation of cell organization and biogenesis" EXACT [] xref: GO:0051130 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0003035 name: regulation of NK T cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer T cell activation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "regulation of natural killer T cell activation" EXACT [] synonym: "regulation of natural T cell activation" EXACT [] synonym: "regulation of NK T lymphocyte activation" EXACT [] synonym: "regulation of NK T-cell activation" EXACT [] synonym: "regulation of NK T-lymphocyte activation" EXACT [] synonym: "regulation of NKT cell activation" EXACT [] synonym: "regulation of NT cell activation" EXACT [] xref: GO:0051133 is_a: CCO:P0002709 ! regulation of alpha-beta T cell activation [Term] id: CCO:P0003036 name: negative regulation of NK T cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of natural killer T cell activation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "down regulation of NK T cell activation" EXACT [] synonym: "down-regulation of NK T cell activation" EXACT [] synonym: "downregulation of NK T cell activation" EXACT [] synonym: "inhibition of NK T cell activation" NARROW [] synonym: "negative regulation of natural killer T cell activation" EXACT [] synonym: "negative regulation of natural T cell activation" EXACT [] synonym: "negative regulation of NK T lymphocyte activation" EXACT [] synonym: "negative regulation of NK T-cell activation" EXACT [] synonym: "negative regulation of NK T-lymphocyte activation" EXACT [] synonym: "negative regulation of NKT cell activation" EXACT [] synonym: "negative regulation of NT cell activation" EXACT [] xref: GO:0051134 is_a: CCO:P0002711 ! negative regulation of alpha-beta T cell activation is_a: CCO:P0003035 ! regulation of NK T cell activation [Term] id: CCO:P0003037 name: positive regulation of NK T cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer T cell activation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "activation of NK T cell activation" NARROW [] synonym: "positive regulation of natural killer T cell activation" EXACT [] synonym: "positive regulation of natural T cell activation" EXACT [] synonym: "positive regulation of NK T lymphocyte activation" EXACT [] synonym: "positive regulation of NK T-cell activation" EXACT [] synonym: "positive regulation of NK T-lymphocyte activation" EXACT [] synonym: "positive regulation of NKT cell activation" EXACT [] synonym: "positive regulation of NT cell activation" EXACT [] synonym: "stimulation of NK T cell activation" NARROW [] synonym: "up regulation of NK T cell activation" EXACT [] synonym: "up-regulation of NK T cell activation" EXACT [] synonym: "upregulation of NK T cell activation" EXACT [] xref: GO:0051135 is_a: CCO:P0002710 ! positive regulation of alpha-beta T cell activation is_a: CCO:P0003035 ! regulation of NK T cell activation [Term] id: CCO:P0003038 name: regulation of NK T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer T cell differentiation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "regulation of natural killer T cell differentiation" EXACT [] synonym: "regulation of natural T cell differentiation" EXACT [] synonym: "regulation of NK T lymphocyte differentiation" EXACT [] synonym: "regulation of NK T-cell differentiation" EXACT [] synonym: "regulation of NK T-lymphocyte differentiation" EXACT [] synonym: "regulation of NKT cell differentiation" EXACT [] synonym: "regulation of NT cell differentiation" EXACT [] xref: GO:0051136 is_a: CCO:P0002712 ! regulation of alpha-beta T cell differentiation [Term] id: CCO:P0003039 name: negative regulation of NK T cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of natural killer T cell differentiation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "down regulation of NK T cell differentiation" EXACT [] synonym: "down-regulation of NK T cell differentiation" EXACT [] synonym: "downregulation of NK T cell differentiation" EXACT [] synonym: "inhibition of NK T cell differentiation" NARROW [] synonym: "negative regulation of natural killer T cell differentiation" EXACT [] synonym: "negative regulation of natural T cell differentiation" EXACT [] synonym: "negative regulation of NK T lymphocyte differentiation" EXACT [] synonym: "negative regulation of NK T-cell differentiation" EXACT [] synonym: "negative regulation of NK T-lymphocyte differentiation" EXACT [] synonym: "negative regulation of NKT cell differentiation" EXACT [] synonym: "negative regulation of NT cell differentiation" EXACT [] xref: GO:0051137 is_a: CCO:P0002714 ! negative regulation of alpha-beta T cell differentiation is_a: CCO:P0003038 ! regulation of NK T cell differentiation [Term] id: CCO:P0003040 name: positive regulation of NK T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "activation of NK T cell differentiation" NARROW [] synonym: "positive regulation of natural killer T cell differentiation" EXACT [] synonym: "positive regulation of natural T cell differentiation" EXACT [] synonym: "positive regulation of NK T lymphocyte differentiation" EXACT [] synonym: "positive regulation of NK T-cell differentiation" EXACT [] synonym: "positive regulation of NK T-lymphocyte differentiation" EXACT [] synonym: "positive regulation of NKT cell differentiation" EXACT [] synonym: "positive regulation of NT cell differentiation" EXACT [] synonym: "stimulation of NK T cell differentiation" NARROW [] synonym: "up regulation of NK T cell differentiation" EXACT [] synonym: "up-regulation of NK T cell differentiation" EXACT [] synonym: "upregulation of NK T cell differentiation" EXACT [] xref: GO:0051138 is_a: CCO:P0002713 ! positive regulation of alpha-beta T cell differentiation is_a: CCO:P0003038 ! regulation of NK T cell differentiation relationship: has_participant CCO:B0054299 ! AP3B1_HUMAN relationship: has_participant CCO:B0054358 ! AP3D1_HUMAN [Term] id: CCO:P0003041 name: regulation of NK T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of natural killer T cell proliferation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "regulation of natural killer T cell proliferation" EXACT [] synonym: "regulation of natural T cell proliferation" EXACT [] synonym: "regulation of NK T lymphocyte proliferation" EXACT [] synonym: "regulation of NK T-cell proliferation" EXACT [] synonym: "regulation of NK T-lymphocyte proliferation" EXACT [] synonym: "regulation of NKT cell proliferation" EXACT [] synonym: "regulation of NT cell proliferation" EXACT [] xref: GO:0051140 is_a: CCO:P0002715 ! regulation of alpha-beta T cell proliferation relationship: regulates CCO:P0000482 ! NK T cell proliferation [Term] id: CCO:P0003042 name: negative regulation of NK T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of natural killer T cell proliferation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "down regulation of NK T cell proliferation" EXACT [] synonym: "down-regulation of NK T cell proliferation" EXACT [] synonym: "downregulation of NK T cell proliferation" EXACT [] synonym: "inhibition of NK T cell proliferation" NARROW [] synonym: "negative regulation of natural killer T cell proliferation" EXACT [] synonym: "negative regulation of natural T cell proliferation" EXACT [] synonym: "negative regulation of NK T lymphocyte proliferation" EXACT [] synonym: "negative regulation of NK T-cell proliferation" EXACT [] synonym: "negative regulation of NK T-lymphocyte proliferation" EXACT [] synonym: "negative regulation of NKT cell proliferation" EXACT [] synonym: "negative regulation of NT cell proliferation" EXACT [] xref: GO:0051141 is_a: CCO:P0002717 ! negative regulation of alpha-beta T cell proliferation is_a: CCO:P0003041 ! regulation of NK T cell proliferation relationship: negatively_regulates CCO:P0000482 ! NK T cell proliferation [Term] id: CCO:P0003043 name: positive regulation of NK T cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation." [ISBN:0781735149 "Fundamental Immunology", PMID:12154375, PMID:9133426] synonym: "activation of NK T cell proliferation" NARROW [] synonym: "positive regulation of natural killer T cell proliferation" EXACT [] synonym: "positive regulation of natural T cell proliferation" EXACT [] synonym: "positive regulation of NK T lymphocyte proliferation" EXACT [] synonym: "positive regulation of NK T-cell proliferation" EXACT [] synonym: "positive regulation of NK T-lymphocyte proliferation" EXACT [] synonym: "positive regulation of NKT cell proliferation" EXACT [] synonym: "positive regulation of NT cell proliferation" EXACT [] synonym: "stimulation of NK T cell proliferation" NARROW [] synonym: "up regulation of NK T cell proliferation" EXACT [] synonym: "up-regulation of NK T cell proliferation" EXACT [] synonym: "upregulation of NK T cell proliferation" EXACT [] xref: GO:0051142 is_a: CCO:P0002716 ! positive regulation of alpha-beta T cell proliferation is_a: CCO:P0003041 ! regulation of NK T cell proliferation relationship: positively_regulates CCO:P0000482 ! NK T cell proliferation [Term] id: CCO:P0003044 name: regulation of muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] xref: GO:0051147 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0003045 name: negative regulation of muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "down regulation of muscle cell differentiation" EXACT [] synonym: "down-regulation of muscle cell differentiation" EXACT [] synonym: "downregulation of muscle cell differentiation" EXACT [] synonym: "inhibition of muscle cell differentiation" NARROW [] xref: GO:0051148 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0003044 ! regulation of muscle cell differentiation [Term] id: CCO:P0003046 name: positive regulation of muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "activation of muscle cell differentiation" NARROW [] synonym: "stimulation of muscle cell differentiation" NARROW [] synonym: "up regulation of muscle cell differentiation" EXACT [] synonym: "up-regulation of muscle cell differentiation" EXACT [] synonym: "upregulation of muscle cell differentiation" EXACT [] xref: GO:0051149 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0003044 ! regulation of muscle cell differentiation [Term] id: CCO:P0003047 name: regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] xref: GO:0051150 is_a: CCO:P0003044 ! regulation of muscle cell differentiation [Term] id: CCO:P0003048 name: negative regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "down regulation of smooth muscle cell differentiation" EXACT [] synonym: "down-regulation of smooth muscle cell differentiation" EXACT [] synonym: "downregulation of smooth muscle cell differentiation" EXACT [] synonym: "inhibition of smooth muscle cell differentiation" NARROW [] xref: GO:0051151 is_a: CCO:P0003045 ! negative regulation of muscle cell differentiation is_a: CCO:P0003047 ! regulation of smooth muscle cell differentiation relationship: has_participant CCO:B0001362 ! EREG_HUMAN relationship: has_participant CCO:B0001706 ! FOXO4_HUMAN relationship: has_participant CCO:B0058878 ! PRDM6_HUMAN [Term] id: CCO:P0003049 name: positive regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "activation of smooth muscle cell differentiation" NARROW [] synonym: "stimulation of smooth muscle cell differentiation" NARROW [] synonym: "up regulation of smooth muscle cell differentiation" EXACT [] synonym: "up-regulation of smooth muscle cell differentiation" EXACT [] synonym: "upregulation of smooth muscle cell differentiation" EXACT [] xref: GO:0051152 is_a: CCO:P0003046 ! positive regulation of muscle cell differentiation is_a: CCO:P0003047 ! regulation of smooth muscle cell differentiation [Term] id: CCO:P0003050 name: regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] xref: GO:0051153 is_a: CCO:P0003044 ! regulation of muscle cell differentiation [Term] id: CCO:P0003051 name: negative regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "down regulation of striated muscle cell differentiation" EXACT [] synonym: "down-regulation of striated muscle cell differentiation" EXACT [] synonym: "downregulation of striated muscle cell differentiation" EXACT [] synonym: "inhibition of striated muscle cell differentiation" NARROW [] xref: GO:0051154 is_a: CCO:P0003045 ! negative regulation of muscle cell differentiation is_a: CCO:P0003050 ! regulation of striated muscle cell differentiation [Term] id: CCO:P0003052 name: positive regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "activation of striated muscle cell differentiation" NARROW [] synonym: "stimulation of striated muscle cell differentiation" NARROW [] synonym: "up regulation of striated muscle cell differentiation" EXACT [] synonym: "up-regulation of striated muscle cell differentiation" EXACT [] synonym: "upregulation of striated muscle cell differentiation" EXACT [] xref: GO:0051155 is_a: CCO:P0003046 ! positive regulation of muscle cell differentiation is_a: CCO:P0003050 ! regulation of striated muscle cell differentiation relationship: has_participant CCO:B0049576 ! NRG1_HUMAN [Term] id: CCO:P0003053 name: regulation of phosphorus metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai] subset: gosubset_prok synonym: "regulation of phosphorus metabolism" EXACT [] xref: GO:0051174 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0003054 name: negative regulation of sulfur metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] subset: gosubset_prok synonym: "down regulation of sulfur metabolic process" EXACT [] synonym: "down-regulation of sulfur metabolic process" EXACT [] synonym: "downregulation of sulfur metabolic process" EXACT [] synonym: "inhibition of sulfur metabolic process" NARROW [] synonym: "negative regulation of sulfur metabolism" EXACT [] synonym: "negative regulation of sulphur metabolic process" EXACT [] synonym: "negative regulation of sulphur metabolism" EXACT [] xref: GO:0051175 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0002124 ! regulation of sulfur metabolic process [Term] id: CCO:P0003055 name: positive regulation of sulfur metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] subset: gosubset_prok synonym: "activation of sulfur metabolic process" NARROW [] synonym: "positive regulation of sulfur metabolism" EXACT [] synonym: "positive regulation of sulphur metabolic process" EXACT [] synonym: "positive regulation of sulphur metabolism" EXACT [] synonym: "stimulation of sulfur metabolic process" NARROW [] synonym: "up regulation of sulfur metabolic process" EXACT [] synonym: "up-regulation of sulfur metabolic process" EXACT [] synonym: "upregulation of sulfur metabolic process" EXACT [] xref: GO:0051176 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0002124 ! regulation of sulfur metabolic process [Term] id: CCO:P0003056 name: regulation of cofactor metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor." [GOC:ai] subset: gosubset_prok synonym: "regulation of cofactor metabolism" EXACT [] xref: GO:0051193 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0003057 name: positive regulation of cofactor metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor." [GOC:ai] subset: gosubset_prok synonym: "activation of cofactor metabolic process" NARROW [] synonym: "positive regulation of cofactor metabolism" EXACT [] synonym: "stimulation of cofactor metabolic process" NARROW [] synonym: "up regulation of cofactor metabolic process" EXACT [] synonym: "up-regulation of cofactor metabolic process" EXACT [] synonym: "upregulation of cofactor metabolic process" EXACT [] xref: GO:0051194 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0003056 ! regulation of cofactor metabolic process [Term] id: CCO:P0003058 name: negative regulation of cofactor metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor." [GOC:ai] subset: gosubset_prok synonym: "down regulation of cofactor metabolic process" EXACT [] synonym: "down-regulation of cofactor metabolic process" EXACT [] synonym: "downregulation of cofactor metabolic process" EXACT [] synonym: "inhibition of cofactor metabolic process" NARROW [] synonym: "negative regulation of cofactor metabolism" EXACT [] xref: GO:0051195 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0003056 ! regulation of cofactor metabolic process [Term] id: CCO:P0003059 name: regulation of coenzyme metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme." [GOC:ai] subset: gosubset_prok synonym: "regulation of coenzyme and prosthetic group metabolic process" BROAD [] synonym: "regulation of coenzyme and prosthetic group metabolism" BROAD [] synonym: "regulation of coenzyme metabolism" EXACT [] xref: GO:0051196 is_a: CCO:P0003056 ! regulation of cofactor metabolic process [Term] id: CCO:P0003060 name: positive regulation of coenzyme metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme." [GOC:ai] subset: gosubset_prok synonym: "activation of coenzyme metabolic process" NARROW [] synonym: "positive regulation of coenzyme and prosthetic group metabolic process" BROAD [] synonym: "positive regulation of coenzyme and prosthetic group metabolism" BROAD [] synonym: "positive regulation of coenzyme metabolism" EXACT [] synonym: "stimulation of coenzyme metabolic process" NARROW [] synonym: "up regulation of coenzyme metabolic process" EXACT [] synonym: "up-regulation of coenzyme metabolic process" EXACT [] synonym: "upregulation of coenzyme metabolic process" EXACT [] xref: GO:0051197 is_a: CCO:P0003057 ! positive regulation of cofactor metabolic process is_a: CCO:P0003059 ! regulation of coenzyme metabolic process [Term] id: CCO:P0003061 name: negative regulation of coenzyme metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme." [GOC:ai] subset: gosubset_prok synonym: "down regulation of coenzyme metabolic process" EXACT [] synonym: "down-regulation of coenzyme metabolic process" EXACT [] synonym: "downregulation of coenzyme metabolic process" EXACT [] synonym: "inhibition of coenzyme metabolic process" NARROW [] synonym: "negative regulation of coenzyme and prosthetic group metabolic process" BROAD [] synonym: "negative regulation of coenzyme and prosthetic group metabolism" BROAD [] synonym: "negative regulation of coenzyme metabolism" EXACT [] xref: GO:0051198 is_a: CCO:P0003058 ! negative regulation of cofactor metabolic process is_a: CCO:P0003059 ! regulation of coenzyme metabolic process [Term] id: CCO:P0003062 name: regulation of prosthetic group metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group." [GOC:ai] subset: gosubset_prok synonym: "regulation of coenzyme and prosthetic group metabolic process" BROAD [] synonym: "regulation of coenzyme and prosthetic group metabolism" BROAD [] synonym: "regulation of prosthetic group metabolism" EXACT [] xref: GO:0051199 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0003063 name: positive regulation of prosthetic group metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group." [GOC:ai] subset: gosubset_prok synonym: "activation of prosthetic group metabolic process" NARROW [] synonym: "positive regulation of coenzyme and prosthetic group metabolic process" BROAD [] synonym: "positive regulation of coenzyme and prosthetic group metabolism" BROAD [] synonym: "positive regulation of prosthetic group metabolism" EXACT [] synonym: "stimulation of prosthetic group metabolic process" NARROW [] synonym: "up regulation of prosthetic group metabolic process" EXACT [] synonym: "up-regulation of prosthetic group metabolic process" EXACT [] synonym: "upregulation of prosthetic group metabolic process" EXACT [] xref: GO:0051200 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0003062 ! regulation of prosthetic group metabolic process [Term] id: CCO:P0003064 name: negative regulation of prosthetic group metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group." [GOC:ai] subset: gosubset_prok synonym: "down regulation of prosthetic group metabolic process" EXACT [] synonym: "down-regulation of prosthetic group metabolic process" EXACT [] synonym: "downregulation of prosthetic group metabolic process" EXACT [] synonym: "inhibition of prosthetic group metabolic process" NARROW [] synonym: "negative regulation of coenzyme and prosthetic group metabolic process" BROAD [] synonym: "negative regulation of coenzyme and prosthetic group metabolism" BROAD [] synonym: "negative regulation of prosthetic group metabolism" EXACT [] xref: GO:0051201 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0003062 ! regulation of prosthetic group metabolic process [Term] id: CCO:P0003065 name: regulation of lymphocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai] xref: GO:0051249 is_a: CCO:P0000562 ! regulation of leukocyte activation relationship: has_participant CCO:B0001490 ! LCK_HUMAN [Term] id: CCO:P0003066 name: negative regulation of lymphocyte activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "down regulation of lymphocyte activation" EXACT [] synonym: "down-regulation of lymphocyte activation" EXACT [] synonym: "downregulation of lymphocyte activation" EXACT [] synonym: "inhibition of lymphocyte activation" NARROW [] xref: GO:0051250 is_a: CCO:P0000563 ! negative regulation of leukocyte activation is_a: CCO:P0003065 ! regulation of lymphocyte activation [Term] id: CCO:P0003067 name: positive regulation of lymphocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "activation of lymphocyte activation" NARROW [] synonym: "stimulation of lymphocyte activation" NARROW [] synonym: "up regulation of lymphocyte activation" EXACT [] synonym: "up-regulation of lymphocyte activation" EXACT [] synonym: "upregulation of lymphocyte activation" EXACT [] xref: GO:0051251 is_a: CCO:P0000564 ! positive regulation of leukocyte activation is_a: CCO:P0003065 ! regulation of lymphocyte activation [Term] id: CCO:P0003068 name: regulation of RNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] subset: gosubset_prok synonym: "regulation of RNA metabolism" EXACT [] xref: GO:0051252 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process relationship: has_participant CCO:B0005995 ! RASA1_HUMAN [Term] id: CCO:P0003069 name: negative regulation of RNA metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] subset: gosubset_prok synonym: "down regulation of RNA metabolic process" EXACT [] synonym: "down-regulation of RNA metabolic process" EXACT [] synonym: "downregulation of RNA metabolic process" EXACT [] synonym: "inhibition of RNA metabolic process" NARROW [] synonym: "negative regulation of RNA metabolism" EXACT [] xref: GO:0051253 is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0003068 ! regulation of RNA metabolic process [Term] id: CCO:P0003070 name: positive regulation of RNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] subset: gosubset_prok synonym: "activation of RNA metabolic process" NARROW [] synonym: "positive regulation of RNA metabolism" EXACT [] synonym: "stimulation of RNA metabolic process" NARROW [] synonym: "up regulation of RNA metabolic process" EXACT [] synonym: "up-regulation of RNA metabolic process" EXACT [] synonym: "upregulation of RNA metabolic process" EXACT [] xref: GO:0051254 is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0003068 ! regulation of RNA metabolic process [Term] id: CCO:P0003071 name: regulation of cell motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the movement of a cell." [GOC:ai] subset: gosubset_prok synonym: "regulation of cell movement" EXACT [] xref: GO:0051270 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0055034 ! B4GT1_HUMAN [Term] id: CCO:P0003072 name: negative regulation of cell motility namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the movement of a cell." [GOC:ai] subset: gosubset_prok synonym: "down regulation of cell motility" EXACT [] synonym: "down-regulation of cell motility" EXACT [] synonym: "downregulation of cell motility" EXACT [] synonym: "inhibition of cell motility" NARROW [] synonym: "negative regulation of cell movement" EXACT [] xref: GO:0051271 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003071 ! regulation of cell motility relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0001624 ! CDN1B_HUMAN relationship: has_participant CCO:B0005948 ! ACTN1_HUMAN relationship: has_participant CCO:B0057919 ! PKHD1_HUMAN [Term] id: CCO:P0003073 name: positive regulation of cell motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the movement of a cell." [GOC:ai] subset: gosubset_prok synonym: "activation of cell motility" NARROW [] synonym: "positive regulation of cell movement" EXACT [] synonym: "stimulation of cell motility" NARROW [] synonym: "up regulation of cell motility" EXACT [] synonym: "up-regulation of cell motility" EXACT [] synonym: "upregulation of cell motility" EXACT [] xref: GO:0051272 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003071 ! regulation of cell motility relationship: has_participant CCO:B0001397 ! ACTN4_HUMAN relationship: has_participant CCO:B0001603 ! BCL6_HUMAN relationship: has_participant CCO:B0005744 ! RS19_HUMAN relationship: has_participant CCO:B0057306 ! PDPN_HUMAN [Term] id: CCO:P0003074 name: regulation of release of sequestered calcium ion into cytosol namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria." [GOC:ai, GOC:tb] synonym: "regulation of calcium ion (Ca2+) mobilization" EXACT [] synonym: "regulation of calcium mobilization" EXACT [] synonym: "regulation of cytoplasmic release of sequestered calcium ion (Ca2+)" EXACT [] synonym: "regulation of cytoplasmic release of stored calcium ion (Ca2+)" EXACT [] synonym: "regulation of release of sequestered calcium ion (Ca2+)" BROAD [] synonym: "regulation of release of stored calcium ion (Ca2+)" BROAD [] synonym: "regulation of release of stored calcium ion (Ca2+) into cytoplasm" EXACT [] synonym: "regulation of release of stored calcium ion (Ca2+) into cytosol" EXACT [] xref: GO:0051279 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0003075 name: negative regulation of release of sequestered calcium ion into cytosol namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria." [GOC:ai] synonym: "down regulation of release of sequestered calcium ion into cytosol" EXACT [] synonym: "down-regulation of release of sequestered calcium ion into cytosol" EXACT [] synonym: "downregulation of release of sequestered calcium ion into cytosol" EXACT [] synonym: "inhibition of release of sequestered calcium ion into cytosol" NARROW [] synonym: "negative regulation of calcium ion (Ca2+) mobilization" BROAD [] synonym: "negative regulation of calcium mobilization" BROAD [] synonym: "negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)" BROAD [] synonym: "negative regulation of cytoplasmic release of stored calcium ion (Ca2+)" BROAD [] synonym: "negative regulation of cytosolic release of sequestered calcium ion (Ca2+)" EXACT [] synonym: "negative regulation of cytosolic release of stored calcium ion (Ca2+)" EXACT [] synonym: "negative regulation of release of sequestered calcium ion (Ca2+)" BROAD [] synonym: "negative regulation of release of sequestered calcium ion into cytoplasm" BROAD [] synonym: "negative regulation of release of stored calcium ion (Ca2+)" BROAD [] synonym: "negative regulation of release of stored calcium ion (Ca2+) into cytoplasm" BROAD [] synonym: "negative regulation of release of stored calcium ion (Ca2+) into cytosol" EXACT [] xref: GO:0051280 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003074 ! regulation of release of sequestered calcium ion into cytosol relationship: has_participant CCO:B0001471 ! TGFB1_HUMAN [Term] id: CCO:P0003076 name: positive regulation of release of sequestered calcium ion into cytosol namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria." [GOC:ai] synonym: "activation of release of sequestered calcium ion into cytosol" NARROW [] synonym: "positive regulation of calcium ion (Ca2+) mobilization" BROAD [] synonym: "positive regulation of calcium mobilization" BROAD [] synonym: "positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)" BROAD [] synonym: "positive regulation of cytoplasmic release of stored calcium ion (Ca2+)" BROAD [] synonym: "positive regulation of cytosolic release of sequestered calcium ion (Ca2+)" EXACT [] synonym: "positive regulation of cytosolic release of stored calcium ion (Ca2+)" EXACT [] synonym: "positive regulation of release of sequestered calcium ion (Ca2+)" BROAD [] synonym: "positive regulation of release of sequestered calcium ion into cytoplasm" BROAD [] synonym: "positive regulation of release of stored calcium ion (Ca2+)" BROAD [] synonym: "positive regulation of release of stored calcium ion (Ca2+) into cytoplasm" BROAD [] synonym: "positive regulation of release of stored calcium ion (Ca2+) into cytosol" EXACT [] synonym: "stimulation of release of sequestered calcium ion into cytosol" NARROW [] synonym: "up regulation of release of sequestered calcium ion into cytosol" EXACT [] synonym: "up-regulation of release of sequestered calcium ion into cytosol" EXACT [] synonym: "upregulation of release of sequestered calcium ion into cytosol" EXACT [] xref: GO:0051281 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003074 ! regulation of release of sequestered calcium ion into cytosol relationship: has_participant CCO:B0054889 ! THY1_HUMAN relationship: has_participant CCO:B0056401 ! Q59GA0_HUMAN [Term] id: CCO:P0003077 name: cell division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators] subset: goslim_pir subset: gosubset_prok xref: GO:0051301 is_a: CCO:P0000887 ! cellular process relationship: has_participant CCO:B0001318 ! A4D1Y2_HUMAN relationship: has_participant CCO:B0001334 ! SAC31_HUMAN relationship: has_participant CCO:B0001346 ! CDC7_HUMAN relationship: has_participant CCO:B0001354 ! UBE2C_HUMAN relationship: has_participant CCO:B0001356 ! CTRO_HUMAN relationship: has_participant CCO:B0001360 ! NDC80_HUMAN relationship: has_participant CCO:B0001368 ! CETN3_HUMAN relationship: has_participant CCO:B0001377 ! BIRC5_HUMAN relationship: has_participant CCO:B0001382 ! SEPT4_HUMAN relationship: has_participant CCO:B0001387 ! ZW10_HUMAN relationship: has_participant CCO:B0001394 ! PRC1_HUMAN relationship: has_participant CCO:B0001395 ! BUB1_HUMAN relationship: has_participant CCO:B0001403 ! RAD21_HUMAN relationship: has_participant CCO:B0001405 ! SSA27_HUMAN relationship: has_participant CCO:B0001408 ! EVI5_HUMAN relationship: has_participant CCO:B0001410 ! CCNT1_HUMAN relationship: has_participant CCO:B0001411 ! BUB1B_HUMAN relationship: has_participant CCO:B0001412 ! CCNT2_HUMAN relationship: has_participant CCO:B0001422 ! CLAP2_HUMAN relationship: has_participant CCO:B0001425 ! TACC1_HUMAN relationship: has_participant CCO:B0001427 ! KTNA1_HUMAN relationship: has_participant CCO:B0001435 ! CD123_HUMAN relationship: has_participant CCO:B0001439 ! CCNK_HUMAN relationship: has_participant CCO:B0001440 ! DCTN3_HUMAN relationship: has_participant CCO:B0001446 ! CCNB2_HUMAN relationship: has_participant CCO:B0001449 ! ZWINT_HUMAN relationship: has_participant CCO:B0001450 ! SMC2_HUMAN relationship: has_participant CCO:B0001454 ! LATS1_HUMAN relationship: has_participant CCO:B0001457 ! PTTG1_HUMAN relationship: has_participant CCO:B0001460 ! CCNE2_HUMAN relationship: has_participant CCO:B0001491 ! RB_HUMAN relationship: has_participant CCO:B0001493 ! CDC2_HUMAN relationship: has_participant CCO:B0001512 ! CDK4_HUMAN relationship: has_participant CCO:B0001519 ! CCNB1_HUMAN relationship: has_participant CCO:B0001533 ! RCC1_HUMAN relationship: has_participant CCO:B0001534 ! DNLI1_HUMAN relationship: has_participant CCO:B0001538 ! CCNA2_HUMAN relationship: has_participant CCO:B0001551 ! CCND1_HUMAN relationship: has_participant CCO:B0001554 ! CCNE1_HUMAN relationship: has_participant CCO:B0001555 ! CDK2_HUMAN relationship: has_participant CCO:B0001573 ! CCND2_HUMAN relationship: has_participant CCO:B0001574 ! CCND3_HUMAN relationship: has_participant CCO:B0001575 ! WEE1_HUMAN relationship: has_participant CCO:B0001576 ! MPIP1_HUMAN relationship: has_participant CCO:B0001577 ! MPIP2_HUMAN relationship: has_participant CCO:B0001578 ! MPIP3_HUMAN relationship: has_participant CCO:B0001586 ! CKS2_HUMAN relationship: has_participant CCO:B0001596 ! PP1G_HUMAN relationship: has_participant CCO:B0001602 ! CCNF_HUMAN relationship: has_participant CCO:B0001604 ! CETN2_HUMAN relationship: has_participant CCO:B0001614 ! CNDD3_HUMAN relationship: has_participant CCO:B0001618 ! LIS1_HUMAN relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: has_participant CCO:B0001638 ! DNLI3_HUMAN relationship: has_participant CCO:B0001639 ! DNLI4_HUMAN relationship: has_participant CCO:B0001644 ! CDK7_HUMAN relationship: has_participant CCO:B0001645 ! KNTC1_HUMAN relationship: has_participant CCO:B0001654 ! NEK2_HUMAN relationship: has_participant CCO:B0001655 ! NEK4_HUMAN relationship: has_participant CCO:B0001656 ! CCNG1_HUMAN relationship: has_participant CCO:B0001659 ! KIF11_HUMAN relationship: has_participant CCO:B0001663 ! PLK1_HUMAN relationship: has_participant CCO:B0001667 ! TERF1_HUMAN relationship: has_participant CCO:B0001686 ! CKS1_HUMAN relationship: has_participant CCO:B0001688 ! PP1A_HUMAN relationship: has_participant CCO:B0001689 ! PP1B_HUMAN relationship: has_participant CCO:B0001696 ! UBC9_HUMAN relationship: has_participant CCO:B0001698 ! MORN_HUMAN relationship: has_participant CCO:B0001701 ! CCNA1_HUMAN relationship: has_participant CCO:B0001702 ! TXN4A_HUMAN relationship: has_participant CCO:B0001707 ! CDK3_HUMAN relationship: has_participant CCO:B0001708 ! CDK6_HUMAN relationship: has_participant CCO:B0001709 ! CDK5_HUMAN relationship: has_participant CCO:B0001715 ! CENPE_HUMAN relationship: has_participant CCO:B0001716 ! KIF23_HUMAN relationship: has_participant CCO:B0001731 ! CETN1_HUMAN relationship: has_participant CCO:B0001733 ! CDC20_HUMAN relationship: has_participant CCO:B0001739 ! CDC16_HUMAN relationship: has_participant CCO:B0001748 ! MD2L1_HUMAN relationship: has_participant CCO:B0001775 ! SEPT6_HUMAN relationship: has_participant CCO:B0001782 ! CASL_HUMAN relationship: has_participant CCO:B0001790 ! SMC1A_HUMAN relationship: has_participant CCO:B0001797 ! CND2_HUMAN relationship: has_participant CCO:B0001800 ! SEPT2_HUMAN relationship: has_participant CCO:B0001801 ! CND1_HUMAN relationship: has_participant CCO:B0001808 ! SYCP1_HUMAN relationship: has_participant CCO:B0001811 ! MARE2_HUMAN relationship: has_participant CCO:B0001812 ! MARE1_HUMAN relationship: has_participant CCO:B0001816 ! SEPT7_HUMAN relationship: has_participant CCO:B0001821 ! CCNG2_HUMAN relationship: has_participant CCO:B0001829 ! PDS5A_HUMAN relationship: has_participant CCO:B0001834 ! MAP9_HUMAN relationship: has_participant CCO:B0001837 ! CEP55_HUMAN relationship: has_participant CCO:B0001839 ! BOREA_HUMAN relationship: has_participant CCO:B0001840 ! SGOL2_HUMAN relationship: has_participant CCO:B0001847 ! SGOL1_HUMAN relationship: has_participant CCO:B0001883 ! QN1_HUMAN relationship: has_participant CCO:B0001896 ! Q5TZP9_HUMAN relationship: has_participant CCO:B0001902 ! POLS_HUMAN relationship: has_participant CCO:B0001905 ! CDCA2_HUMAN relationship: has_participant CCO:B0001906 ! CYTSA_HUMAN relationship: has_participant CCO:B0001912 ! PMF1_HUMAN relationship: has_participant CCO:B0001913 ! L2GL2_HUMAN relationship: has_participant CCO:B0001914 ! BORA_HUMAN relationship: has_participant CCO:B0001915 ! SYCE2_HUMAN relationship: has_participant CCO:B0001916 ! DCR1A_HUMAN relationship: has_participant CCO:B0001925 ! SEP14_HUMAN relationship: has_participant CCO:B0001930 ! MAEA_HUMAN relationship: has_participant CCO:B0001933 ! CLAP1_HUMAN relationship: has_participant CCO:B0001935 ! Q7Z774_HUMAN relationship: has_participant CCO:B0001940 ! CUZD1_HUMAN relationship: has_participant CCO:B0001941 ! NIPA_HUMAN relationship: has_participant CCO:B0001943 ! CNDG2_HUMAN relationship: has_participant CCO:B0001951 ! SIRT2_HUMAN relationship: has_participant CCO:B0001955 ! CCRK_HUMAN relationship: has_participant CCO:B0001956 ! ASPM_HUMAN relationship: has_participant CCO:B0001957 ! SYCP3_HUMAN relationship: has_participant CCO:B0001960 ! SYCE1_HUMAN relationship: has_participant CCO:B0001961 ! CNTRB_HUMAN relationship: has_participant CCO:B0001962 ! STAG2_HUMAN relationship: has_participant CCO:B0001963 ! KIF2B_HUMAN relationship: has_participant CCO:B0001973 ! SPC24_HUMAN relationship: has_participant CCO:B0001975 ! PAPD5_HUMAN relationship: has_participant CCO:B0001986 ! CDC26_HUMAN relationship: has_participant CCO:B0001991 ! NEK9_HUMAN relationship: has_participant CCO:B0001994 ! CABL1_HUMAN relationship: has_participant CCO:B0001996 ! PARD3_HUMAN relationship: has_participant CCO:B0001997 ! PAR3L_HUMAN relationship: has_participant CCO:B0002001 ! Q8WUE3_HUMAN relationship: has_participant CCO:B0002003 ! SKA2_HUMAN relationship: has_participant CCO:B0002004 ! STAG1_HUMAN relationship: has_participant CCO:B0002007 ! CCNB3_HUMAN relationship: has_participant CCO:B0002011 ! SEPT1_HUMAN relationship: has_participant CCO:B0002032 ! SKA1_HUMAN relationship: has_participant CCO:B0002034 ! CCDC5_HUMAN relationship: has_participant CCO:B0002035 ! CHFR_HUMAN relationship: has_participant CCO:B0002038 ! CDCA5_HUMAN relationship: has_participant CCO:B0002040 ! AURKB_HUMAN relationship: has_participant CCO:B0002041 ! SENP5_HUMAN relationship: has_participant CCO:B0002043 ! NSL1_HUMAN relationship: has_participant CCO:B0002047 ! LMLN_HUMAN relationship: has_participant CCO:B0002051 ! ZN830_HUMAN relationship: has_participant CCO:B0002055 ! NEK1_HUMAN relationship: has_participant CCO:B0002056 ! MPPH1_HUMAN relationship: has_participant CCO:B0002058 ! SPAG5_HUMAN relationship: has_participant CCO:B0002076 ! CDCA3_HUMAN relationship: has_participant CCO:B0002085 ! SEPT5_HUMAN relationship: has_participant CCO:B0002087 ! CDC6_HUMAN relationship: has_participant CCO:B0002092 ! CND3_HUMAN relationship: has_participant CCO:B0002095 ! APC13_HUMAN relationship: has_participant CCO:B0002097 ! CABL2_HUMAN relationship: has_participant CCO:B0002100 ! KTNB1_HUMAN relationship: has_participant CCO:B0002104 ! TIPIN_HUMAN relationship: has_participant CCO:B0002105 ! KIFC1_HUMAN relationship: has_participant CCO:B0002106 ! SYCP2_HUMAN relationship: has_participant CCO:B0002108 ! NUSAP_HUMAN relationship: has_participant CCO:B0002112 ! PAR6G_HUMAN relationship: has_participant CCO:B0002113 ! PAR6B_HUMAN relationship: has_participant CCO:B0002115 ! NUF2_HUMAN relationship: has_participant CCO:B0002122 ! MIS12_HUMAN relationship: has_participant CCO:B0002124 ! RGAP1_HUMAN relationship: has_participant CCO:B0002125 ! APC1_HUMAN relationship: has_participant CCO:B0002127 ! Q9H2F0_HUMAN relationship: has_participant CCO:B0002134 ! DSN1_HUMAN relationship: has_participant CCO:B0002143 ! SPC25_HUMAN relationship: has_participant CCO:B0002145 ! NEK6_HUMAN relationship: has_participant CCO:B0002150 ! PAR6A_HUMAN relationship: has_participant CCO:B0002154 ! INCE_HUMAN relationship: has_participant CCO:B0002155 ! ANLN_HUMAN relationship: has_participant CCO:B0002156 ! BIN3_HUMAN relationship: has_participant CCO:B0002159 ! LATS2_HUMAN relationship: has_participant CCO:B0002161 ! HELLS_HUMAN relationship: has_participant CCO:B0002168 ! SMC4_HUMAN relationship: has_participant CCO:B0002169 ! SEP11_HUMAN relationship: has_participant CCO:B0002173 ! NDE1_HUMAN relationship: has_participant CCO:B0002177 ! APC11_HUMAN relationship: has_participant CCO:B0002183 ! SEP10_HUMAN relationship: has_participant CCO:B0002186 ! RCC2_HUMAN relationship: has_participant CCO:B0002198 ! SEPT3_HUMAN relationship: has_participant CCO:B0002201 ! SEPT9_HUMAN relationship: has_participant CCO:B0002204 ! MD2L2_HUMAN relationship: has_participant CCO:B0002212 ! CDC23_HUMAN relationship: has_participant CCO:B0002213 ! APC7_HUMAN relationship: has_participant CCO:B0002214 ! APC5_HUMAN relationship: has_participant CCO:B0002215 ! APC4_HUMAN relationship: has_participant CCO:B0002216 ! ANC2_HUMAN relationship: has_participant CCO:B0002221 ! FBX5_HUMAN relationship: has_participant CCO:B0002229 ! FZR_HUMAN relationship: has_participant CCO:B0002230 ! APC10_HUMAN relationship: has_participant CCO:B0002233 ! CC14A_HUMAN relationship: has_participant CCO:B0002235 ! TIM_HUMAN relationship: has_participant CCO:B0002238 ! MARE3_HUMAN relationship: has_participant CCO:B0002243 ! SMC3_HUMAN relationship: has_participant CCO:B0002249 ! RUVB1_HUMAN relationship: has_participant CCO:B0002250 ! NUDC_HUMAN relationship: has_participant CCO:B0002257 ! CD2AP_HUMAN relationship: has_participant CCO:B0002264 ! MD1L1_HUMAN relationship: has_participant CCO:B0005426 ! CENPJ_HUMAN relationship: has_participant CCO:B0005841 ! BCAR1_HUMAN relationship: has_participant CCO:B0015090 ! Q5QPR4_HUMAN relationship: has_participant CCO:B0015092 ! Q5QPR3_HUMAN relationship: has_participant CCO:B0017386 ! Q7Z651_HUMAN relationship: has_participant CCO:B0018116 ! Q6JSD6_HUMAN relationship: has_participant CCO:B0018148 ! Q5JU07_HUMAN relationship: has_participant CCO:B0018153 ! Q5JU06_HUMAN relationship: has_participant CCO:B0018187 ! Q5JWU1_HUMAN relationship: has_participant CCO:B0019420 ! Q53FN2_HUMAN relationship: has_participant CCO:B0023207 ! Q5JQZ9_HUMAN relationship: has_participant CCO:B0025091 ! Q5SRN1_HUMAN relationship: has_participant CCO:B0026253 ! SEP12_HUMAN relationship: has_participant CCO:B0026257 ! PDS5B_HUMAN relationship: has_participant CCO:B0032821 ! ZWILC_HUMAN relationship: has_participant CCO:B0035936 ! RNF8_HUMAN relationship: has_participant CCO:B0035938 ! SETD8_HUMAN relationship: has_participant CCO:B0039949 ! FSD1_HUMAN relationship: has_participant CCO:B0041249 ! HMGA2_HUMAN relationship: has_participant CCO:B0041256 ! ERC6L_HUMAN relationship: has_participant CCO:B0041257 ! E4F1_HUMAN relationship: has_participant CCO:B0041260 ! CP110_HUMAN relationship: has_participant CCO:B0041266 ! CINP_HUMAN relationship: has_participant CCO:B0041934 ! B1AMW7_HUMAN relationship: has_participant CCO:B0048576 ! B1AHB1_HUMAN relationship: has_participant CCO:B0056409 ! Q59GL4_HUMAN relationship: has_participant CCO:B0056512 ! Q5JYX0_HUMAN relationship: has_participant CCO:B0056535 ! Q5SRM8_HUMAN relationship: has_participant CCO:B0058396 ! Q96SZ0_HUMAN [Term] id: CCO:P0003078 name: regulation of cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators] subset: gosubset_prok xref: GO:0051302 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0001994 ! CABL1_HUMAN relationship: has_participant CCO:B0002097 ! CABL2_HUMAN relationship: regulates CCO:P0003077 ! cell division [Term] id: CCO:P0003079 name: chromosome movement towards spindle pole namespace: biological_process def: "The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes." [GOC:ai] synonym: "chromosome migration to spindle pole" EXACT [] synonym: "chromosome movement" BROAD [] synonym: "chromosome movement to spindle pole" EXACT [] xref: GO:0051305 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0003080 name: metaphase plate congression namespace: biological_process def: "The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle." [GOC:ai] xref: GO:0051310 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0001629 ! CENPF_HUMAN relationship: part_of CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0003081 name: attachment of spindle microtubules to chromosome namespace: biological_process def: "The process by which spindle microtubules become physically associated with a chromosome." [GOC:ai] synonym: "microtubule and chromosome interaction" BROAD [] synonym: "spindle chromosome attachment" EXACT [] synonym: "spindle-chromosome interaction" BROAD [] xref: GO:0051313 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0003082 name: regulation of nerve growth factor receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor receptor signaling pathway." [GOC:ai] synonym: "regulation of nerve growth factor receptor signalling pathway" EXACT [] synonym: "regulation of NGF receptor signaling pathway" EXACT [] synonym: "regulation of NGF receptor signalling pathway" EXACT [] xref: GO:0051386 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0002757 ! nerve growth factor receptor signaling pathway [Term] id: CCO:P0003083 name: negative regulation of nerve growth factor receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the nerve growth factor receptor signaling pathway." [GOC:ai] synonym: "down regulation of nerve growth factor receptor signaling pathway" EXACT [] synonym: "down-regulation of nerve growth factor receptor signaling pathway" EXACT [] synonym: "downregulation of nerve growth factor receptor signaling pathway" EXACT [] synonym: "inhibition of nerve growth factor receptor signaling pathway" NARROW [] synonym: "negative regulation of nerve growth factor receptor signalling pathway" EXACT [] synonym: "negative regulation of NGF receptor signaling pathway" EXACT [] synonym: "negative regulation of NGF receptor signalling pathway" EXACT [] xref: GO:0051387 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0003082 ! regulation of nerve growth factor receptor signaling pathway relationship: has_participant CCO:B0032938 ! ANGT_HUMAN relationship: has_participant CCO:B0055442 ! AGTR2_HUMAN relationship: negatively_regulates CCO:P0002757 ! nerve growth factor receptor signaling pathway [Term] id: CCO:P0003084 name: positive regulation of nerve growth factor receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor receptor signaling pathway." [GOC:ai] synonym: "activation of nerve growth factor receptor signaling pathway" NARROW [] synonym: "positive regulation of nerve growth factor receptor signalling pathway" EXACT [] synonym: "positive regulation of NGF receptor signaling pathway" EXACT [] synonym: "positive regulation of NGF receptor signalling pathway" EXACT [] synonym: "stimulation of nerve growth factor receptor signaling pathway" NARROW [] synonym: "up regulation of nerve growth factor receptor signaling pathway" EXACT [] synonym: "up-regulation of nerve growth factor receptor signaling pathway" EXACT [] synonym: "upregulation of nerve growth factor receptor signaling pathway" EXACT [] xref: GO:0051388 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0003082 ! regulation of nerve growth factor receptor signaling pathway relationship: positively_regulates CCO:P0002757 ! nerve growth factor receptor signaling pathway [Term] id: CCO:P0003085 name: inactivation of MAPKK activity namespace: biological_process def: "Any process that terminates the activity of the active enzyme MAP kinase kinase." [GOC:ai] synonym: "inactivation of MAP kinase kinase activity" EXACT [] synonym: "termination of MAP kinase kinase activity" EXACT [] synonym: "termination of MAPKK activity" EXACT [] xref: GO:0051389 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0003086 name: inactivation of MAPKKK activity namespace: biological_process def: "Any process that terminates the activity of the active enzyme MAP kinase kinase kinase." [GOC:ai] synonym: "inactivation of MAP kinase kinase kinase activity" EXACT [] synonym: "termination of MAP kinase kinase kinase activity" EXACT [] synonym: "termination of MAPKKK activity" EXACT [] xref: GO:0051390 is_a: CCO:U0000002 ! biological process relationship: part_of CCO:P0000403 ! MAPKKK cascade [Term] id: CCO:P0003087 name: regulation of nerve growth factor receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor receptor." [GOC:ai] synonym: "regulation of NGF receptor activity" EXACT [] xref: GO:0051394 is_a: CCO:P0003082 ! regulation of nerve growth factor receptor signaling pathway [Term] id: CCO:P0003088 name: negative regulation of nerve growth factor receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the nerve growth factor receptor." [GOC:ai] synonym: "down regulation of nerve growth factor receptor activity" EXACT [] synonym: "down-regulation of nerve growth factor receptor activity" EXACT [] synonym: "downregulation of nerve growth factor receptor activity" EXACT [] synonym: "inhibition of nerve growth factor receptor activity" NARROW [] synonym: "negative regulation of NGF receptor activity" EXACT [] xref: GO:0051395 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0003087 ! regulation of nerve growth factor receptor activity [Term] id: CCO:P0003089 name: positive regulation of nerve growth factor receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor receptor." [GOC:ai] synonym: "activation of nerve growth factor receptor activity" NARROW [] synonym: "positive regulation of NGF receptor activity" EXACT [] synonym: "stimulation of nerve growth factor receptor activity" NARROW [] synonym: "up regulation of nerve growth factor receptor activity" EXACT [] synonym: "up-regulation of nerve growth factor receptor activity" EXACT [] synonym: "upregulation of nerve growth factor receptor activity" EXACT [] xref: GO:0051396 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0003087 ! regulation of nerve growth factor receptor activity [Term] id: CCO:P0003090 name: stress-activated MAPK cascade namespace: biological_process def: "A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase." [GOC:ai, PMID:15936270] synonym: "p38 MAPK signaling" EXACT [] synonym: "p38 MAPK signalling" EXACT [] synonym: "stress-activated MAPK signaling pathway" EXACT [] synonym: "stress-activated MAPK signalling pathway" EXACT [] synonym: "stress-activated MAPKKK cascade" EXACT [] synonym: "stress-activated MAPKKK signaling pathway" EXACT [] synonym: "stress-activated MAPKKK signalling pathway" EXACT [] xref: GO:0051403 is_a: CCO:P0000403 ! MAPKKK cascade is_a: CCO:P0001379 ! stress-activated protein kinase signaling pathway relationship: has_participant CCO:B0020951 ! MP2K7_HUMAN relationship: has_participant CCO:B0058509 ! CCM2_HUMAN [Term] id: CCO:P0003091 name: myoblast proliferation namespace: biological_process def: "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] xref: GO:0051450 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0005438 ! MET_HUMAN relationship: has_participant CCO:B0043821 ! IGF1B_HUMAN [Term] id: CCO:P0003092 name: regulation of adrenocorticotropin hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of adrenocorticotropic hormone from a cell or group of cells." [GOC:ai, GOC:dph] synonym: "regulation of adrenocorticotropic hormone secreteion" EXACT [GOC:dph] synonym: "regulation of adrenocorticotropin secretion" EXACT [] synonym: "regulation of adrenotropin hormone secretion" EXACT [] synonym: "regulation of adrenotropin secretion" EXACT [] synonym: "regulation of ATCH secretion" EXACT [] synonym: "regulation of corticotropic hormone secretion" EXACT [] synonym: "regulation of corticotropin secretion" EXACT [] xref: GO:0051459 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0003093 name: negative regulation of adrenocorticotropic hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of adrenocorticotropin hormone from a cell or group of cells." [GOC:ai] synonym: "down regulation of adrenocorticotropin hormone secretion" EXACT [] synonym: "down-regulation of adrenocorticotropin hormone secretion" EXACT [] synonym: "downregulation of adrenocorticotropin hormone secretion" EXACT [] synonym: "inhibition of adrenocorticotropin hormone secretion" NARROW [] synonym: "negative regulation of adrenocorticotropin secretion" EXACT [] synonym: "negative regulation of adrenotropic hormone secretion" EXACT [] synonym: "negative regulation of adrenotropin secretion" EXACT [] synonym: "negative regulation of ATCH secretion" EXACT [] synonym: "negative regulation of corticotropic hormone secretion" EXACT [] synonym: "negative regulation of corticotropin secretion" EXACT [] xref: GO:0051460 is_a: CCO:P0002748 ! negative regulation of hormone secretion is_a: CCO:P0003092 ! regulation of adrenocorticotropin hormone secretion [Term] id: CCO:P0003094 name: positive regulation of adrenocorticotropic hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of adrenocorticotropin hormone from a cell or group of cells." [GOC:ai] synonym: "activation of adrenocorticotropin hormone secretion" NARROW [] synonym: "positive regulation of adrenocorticotropin secretion" EXACT [] synonym: "positive regulation of adrenotropic hormone secretion" EXACT [] synonym: "positive regulation of adrenotropin secretion" EXACT [] synonym: "positive regulation of ATCH secretion" EXACT [] synonym: "positive regulation of corticotropic hormone secretion" EXACT [] synonym: "positive regulation of corticotropin secretion" EXACT [] synonym: "stimulation of adrenocorticotropin hormone secretion" NARROW [] synonym: "up regulation of adrenocorticotropin hormone secretion" EXACT [] synonym: "up-regulation of adrenocorticotropin hormone secretion" EXACT [] synonym: "upregulation of adrenocorticotropin hormone secretion" EXACT [] xref: GO:0051461 is_a: CCO:P0002747 ! positive regulation of hormone secretion is_a: CCO:P0003092 ! regulation of adrenocorticotropin hormone secretion [Term] id: CCO:P0003095 name: regulation of cortisol secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell or group of cells." [GOC:ai] xref: GO:0051462 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0003096 name: negative regulation of cortisol secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of cortisol from a cell or group of cells." [GOC:ai] synonym: "down regulation of cortisol secretion" EXACT [] synonym: "down-regulation of cortisol secretion" EXACT [] synonym: "downregulation of cortisol secretion" EXACT [] synonym: "inhibition of cortisol secretion" NARROW [] xref: GO:0051463 is_a: CCO:P0002748 ! negative regulation of hormone secretion is_a: CCO:P0003095 ! regulation of cortisol secretion [Term] id: CCO:P0003097 name: positive regulation of cortisol secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell or group of cells." [GOC:ai] synonym: "activation of cortisol secretion" NARROW [] synonym: "stimulation of cortisol secretion" NARROW [] synonym: "up regulation of cortisol secretion" EXACT [] synonym: "up-regulation of cortisol secretion" EXACT [] synonym: "upregulation of cortisol secretion" EXACT [] xref: GO:0051464 is_a: CCO:P0002747 ! positive regulation of hormone secretion is_a: CCO:P0003095 ! regulation of cortisol secretion [Term] id: CCO:P0003098 name: negative regulation of corticotropin-releasing hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell or group of cells." [GOC:ai] synonym: "down regulation of corticotropin-releasing hormone secretion" EXACT [] synonym: "down-regulation of corticotropin-releasing hormone secretion" EXACT [] synonym: "downregulation of corticotropin-releasing hormone secretion" EXACT [] synonym: "inhibition of corticotropin-releasing hormone secretion" NARROW [] synonym: "negative regulation of corticotropin-releasing factor secretion" EXACT [] synonym: "negative regulation of CRF secretion" EXACT [] synonym: "negative regulation of CRH secretion" EXACT [] xref: GO:0051465 is_a: CCO:P0002206 ! regulation of corticotropin-releasing hormone secretion is_a: CCO:P0002748 ! negative regulation of hormone secretion [Term] id: CCO:P0003099 name: positive regulation of corticotropin-releasing hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell or group of cells." [GOC:ai] synonym: "activation of corticotropin-releasing hormone secretion" NARROW [] synonym: "positive regulation of corticotropin-releasing factor secretion" EXACT [] synonym: "positive regulation of CRF secretion" EXACT [] synonym: "positive regulation of CRH secretion" EXACT [] synonym: "stimulation of corticotropin-releasing hormone secretion" NARROW [] synonym: "up regulation of corticotropin-releasing hormone secretion" EXACT [] synonym: "up-regulation of corticotropin-releasing hormone secretion" EXACT [] synonym: "upregulation of corticotropin-releasing hormone secretion" EXACT [] xref: GO:0051466 is_a: CCO:P0002206 ! regulation of corticotropin-releasing hormone secretion is_a: CCO:P0002747 ! positive regulation of hormone secretion [Term] id: CCO:P0003100 name: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) namespace: biological_process def: "Any process that increases the concentration of calcium ions in the cytosol during the process of G-protein signaling coupled to IP3 second messenger." [GOC:ai] synonym: "elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" BROAD [] synonym: "elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] synonym: "elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)" BROAD [] synonym: "elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" BROAD [] synonym: "elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)" EXACT [] xref: GO:0051482 is_a: CCO:U0000002 ! biological process relationship: has_participant CCO:B0043822 ! EDN1_HUMAN relationship: has_participant CCO:B0048975 ! TGM2_HUMAN relationship: has_participant CCO:B0054845 ! CALC_HUMAN relationship: has_participant CCO:B0054907 ! CALCA_HUMAN relationship: has_participant CCO:B0055223 ! AGTR1_HUMAN relationship: has_participant CCO:B0058918 ! RL3R1_HUMAN relationship: part_of CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) [Term] id: CCO:P0003101 name: regulation of filopodium formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone." [GOC:ai] synonym: "regulation of filopodia biosynthesis" EXACT [] synonym: "regulation of filopodia formation" EXACT [] xref: GO:0051489 is_a: CCO:P0001421 ! regulation of cell projection organization and biogenesis [Term] id: CCO:P0003102 name: negative regulation of filopodium formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone." [GOC:ai] synonym: "down regulation of filopodium formation" EXACT [] synonym: "down-regulation of filopodium formation" EXACT [] synonym: "downregulation of filopodium formation" EXACT [] synonym: "inhibition of filopodium formation" NARROW [] synonym: "negative regulation of filopodia biosynthesis" EXACT [] synonym: "negative regulation of filopodia formation" EXACT [] xref: GO:0051490 is_a: CCO:P0001422 ! negative regulation of cell projection organization and biogenesis is_a: CCO:P0003101 ! regulation of filopodium formation [Term] id: CCO:P0003103 name: positive regulation of filopodium formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone." [GOC:ai] synonym: "activation of filopodium formation" NARROW [] synonym: "positive regulation of filopodia biosynthesis" EXACT [] synonym: "positive regulation of filopodia formation" EXACT [] synonym: "stimulation of filopodium formation" NARROW [] synonym: "up regulation of filopodium formation" EXACT [] synonym: "up-regulation of filopodium formation" EXACT [] synonym: "upregulation of filopodium formation" EXACT [] xref: GO:0051491 is_a: CCO:P0001423 ! positive regulation of cell projection organization and biogenesis is_a: CCO:P0003101 ! regulation of filopodium formation relationship: has_participant CCO:B0002052 ! CEND2_HUMAN [Term] id: CCO:P0003104 name: regulation of stress fiber formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts." [GOC:ai] synonym: "regulation of stress fibre biosynthesis" EXACT [] synonym: "regulation of stress fibre formation" EXACT [] xref: GO:0051492 is_a: CCO:P0001569 ! regulation of actin filament bundle formation relationship: has_participant CCO:B0002014 ! TSC1_HUMAN [Term] id: CCO:P0003105 name: regulation of cytoskeleton organization and biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] xref: GO:0051493 is_a: CCO:P0001765 ! regulation of organelle organization and biogenesis relationship: has_participant CCO:B0023039 ! STMN3_HUMAN relationship: has_participant CCO:B0055833 ! NEXN_HUMAN relationship: has_participant CCO:B0057431 ! CRPAK_HUMAN [Term] id: CCO:P0003106 name: negative regulation of cytoskeleton organization and biogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "down regulation of cytoskeleton organization and biogenesis" EXACT [] synonym: "down-regulation of cytoskeleton organization and biogenesis" EXACT [] synonym: "downregulation of cytoskeleton organization and biogenesis" EXACT [] synonym: "inhibition of cytoskeleton organization and biogenesis" NARROW [] xref: GO:0051494 is_a: CCO:P0001028 ! negative regulation of organelle organization and biogenesis is_a: CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis [Term] id: CCO:P0003107 name: positive regulation of cytoskeleton organization and biogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "activation of cytoskeleton organization and biogenesis" NARROW [] synonym: "stimulation of cytoskeleton organization and biogenesis" NARROW [] synonym: "up regulation of cytoskeleton organization and biogenesis" EXACT [] synonym: "up-regulation of cytoskeleton organization and biogenesis" EXACT [] synonym: "upregulation of cytoskeleton organization and biogenesis" EXACT [] xref: GO:0051495 is_a: CCO:P0001027 ! positive regulation of organelle organization and biogenesis is_a: CCO:P0003105 ! regulation of cytoskeleton organization and biogenesis relationship: has_participant CCO:B0054564 ! VINEX_HUMAN relationship: has_participant CCO:B0058424 ! P2RX7_HUMAN [Term] id: CCO:P0003108 name: positive regulation of stress fiber formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts." [GOC:ai] synonym: "activation of stress fiber formation" NARROW [] synonym: "positive regulation of stress fibre biosynthesis" EXACT [] synonym: "positive regulation of stress fibre formation" EXACT [] synonym: "stimulation of stress fiber formation" NARROW [] synonym: "up regulation of stress fiber formation" EXACT [] synonym: "up-regulation of stress fiber formation" EXACT [] synonym: "upregulation of stress fiber formation" EXACT [] xref: GO:0051496 is_a: CCO:P0001571 ! positive regulation of actin filament bundle formation is_a: CCO:P0003104 ! regulation of stress fiber formation relationship: has_participant CCO:B0001592 ! MERL_HUMAN relationship: has_participant CCO:B0054564 ! VINEX_HUMAN relationship: has_participant CCO:B0056666 ! Q5VXI4_HUMAN [Term] id: CCO:P0003109 name: negative regulation of stress fiber formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts." [GOC:ai] synonym: "down regulation of stress fiber formation" EXACT [] synonym: "down-regulation of stress fiber formation" EXACT [] synonym: "downregulation of stress fiber formation" EXACT [] synonym: "inhibition of stress fiber formation" NARROW [] synonym: "negative regulation of stress fibre biosynthesis" EXACT [] synonym: "negative regulation of stress fibre formation" EXACT [] xref: GO:0051497 is_a: CCO:P0001570 ! negative regulation of actin filament bundle formation is_a: CCO:P0003104 ! regulation of stress fiber formation relationship: has_participant CCO:B0002052 ! CEND2_HUMAN relationship: has_participant CCO:B0016790 ! RHG07_HUMAN [Term] id: CCO:P0003110 name: regulation of unidimensional cell growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process by which a cell irreversibly increases in size in one [spatial] dimension or along one axis." [GOC:ai] xref: GO:0051510 is_a: CCO:P0000466 ! regulation of cell growth [Term] id: CCO:P0003111 name: negative regulation of unidimensional cell growth namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of unidimensional cell growth, the process by which a cell irreversibly increases in size in one [spatial] dimension or along one axis." [GOC:ai] synonym: "down regulation of unidimensional cell growth" EXACT [] synonym: "down-regulation of unidimensional cell growth" EXACT [] synonym: "downregulation of unidimensional cell growth" EXACT [] synonym: "inhibition of unidimensional cell growth" NARROW [] xref: GO:0051511 is_a: CCO:P0001255 ! negative regulation of cell growth is_a: CCO:P0003110 ! regulation of unidimensional cell growth [Term] id: CCO:P0003112 name: positive regulation of unidimensional cell growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process by which a cell irreversibly increases in size in one [spatial] dimension or along one axis." [GOC:ai] synonym: "activation of unidimensional cell growth" NARROW [] synonym: "stimulation of unidimensional cell growth" NARROW [] synonym: "up regulation of unidimensional cell growth" EXACT [] synonym: "up-regulation of unidimensional cell growth" EXACT [] synonym: "upregulation of unidimensional cell growth" EXACT [] xref: GO:0051512 is_a: CCO:P0001254 ! positive regulation of cell growth is_a: CCO:P0003110 ! regulation of unidimensional cell growth [Term] id: CCO:P0003113 name: regulation of monopolar cell growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] xref: GO:0051513 is_a: CCO:P0003110 ! regulation of unidimensional cell growth [Term] id: CCO:P0003114 name: negative regulation of monopolar cell growth namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] synonym: "down regulation of monopolar cell growth" EXACT [] synonym: "down-regulation of monopolar cell growth" EXACT [] synonym: "downregulation of monopolar cell growth" EXACT [] synonym: "inhibition of monopolar cell growth" NARROW [] xref: GO:0051514 is_a: CCO:P0003111 ! negative regulation of unidimensional cell growth is_a: CCO:P0003113 ! regulation of monopolar cell growth [Term] id: CCO:P0003115 name: positive regulation of monopolar cell growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] synonym: "stimulation of monopolar cell growth" NARROW [] synonym: "up regulation of monopolar cell growth" EXACT [] synonym: "up-regulation of monopolar cell growth" EXACT [] synonym: "upregulation of monopolar cell growth" EXACT [] xref: GO:0051515 is_a: CCO:P0003112 ! positive regulation of unidimensional cell growth is_a: CCO:P0003113 ! regulation of monopolar cell growth [Term] id: CCO:P0003116 name: regulation of bipolar cell growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] xref: GO:0051516 is_a: CCO:P0003110 ! regulation of unidimensional cell growth [Term] id: CCO:P0003117 name: negative regulation of bipolar cell growth namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] synonym: "down regulation of bipolar cell growth" EXACT [] synonym: "down-regulation of bipolar cell growth" EXACT [] synonym: "downregulation of bipolar cell growth" EXACT [] synonym: "inhibition of bipolar cell growth" NARROW [] xref: GO:0051517 is_a: CCO:P0003111 ! negative regulation of unidimensional cell growth is_a: CCO:P0003116 ! regulation of bipolar cell growth [Term] id: CCO:P0003118 name: positive regulation of bipolar cell growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] synonym: "stimulation of bipolar cell growth" NARROW [] synonym: "up regulation of bipolar cell growth" EXACT [] synonym: "up-regulation of bipolar cell growth" EXACT [] synonym: "upregulation of bipolar cell growth" EXACT [] xref: GO:0051518 is_a: CCO:P0003112 ! positive regulation of unidimensional cell growth is_a: CCO:P0003116 ! regulation of bipolar cell growth [Term] id: CCO:P0003119 name: activation of bipolar cell growth namespace: biological_process def: "Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] synonym: "NETO" NARROW [] synonym: "new end take off" NARROW [] synonym: "new end take-off" NARROW [] xref: GO:0051519 is_a: CCO:P0003118 ! positive regulation of bipolar cell growth [Term] id: CCO:P0003120 name: termination of bipolar cell growth namespace: biological_process def: "Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell." [GOC:ai] xref: GO:0051520 is_a: CCO:P0003117 ! negative regulation of bipolar cell growth [Term] id: CCO:P0003121 name: termination of monopolar cell growth namespace: biological_process def: "Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell." [GOC:ai] xref: GO:0051521 is_a: CCO:P0003114 ! negative regulation of monopolar cell growth [Term] id: CCO:P0003122 name: activation of monopolar cell growth namespace: biological_process def: "Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell." [GOC:ai] xref: GO:0051522 is_a: CCO:P0003115 ! positive regulation of monopolar cell growth [Term] id: CCO:P0003123 name: cell growth mode switching, monopolar to bipolar namespace: biological_process def: "The process by which a cell switches from monopolar cell growth to bipolar cell growth." [GOC:ai] xref: GO:0051523 is_a: CCO:P0003110 ! regulation of unidimensional cell growth [Term] id: CCO:P0003124 name: cell growth mode switch, bipolar to monopolar namespace: biological_process def: "The process by which a cell switches from bipolar cell growth to monopolar cell growth." [GOC:ai] xref: GO:0051524 is_a: CCO:P0003110 ! regulation of unidimensional cell growth [Term] id: CCO:P0003125 name: regulation of elastin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin." [GOC:ai] xref: GO:0051543 is_a: CCO:P0000982 ! regulation of glycoprotein biosynthetic process [Term] id: CCO:P0003126 name: positive regulation of elastin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin." [GOC:ai] synonym: "activation of elastin biosynthetic process" NARROW [] synonym: "stimulation of elastin biosynthetic process" NARROW [] synonym: "up regulation of elastin biosynthetic process" EXACT [] synonym: "up-regulation of elastin biosynthetic process" EXACT [] synonym: "upregulation of elastin biosynthetic process" EXACT [] xref: GO:0051544 is_a: CCO:P0000983 ! positive regulation of glycoprotein biosynthetic process is_a: CCO:P0002524 ! positive regulation of translation is_a: CCO:P0003125 ! regulation of elastin biosynthetic process [Term] id: CCO:P0003127 name: negative regulation of elastin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin." [GOC:ai] synonym: "down regulation of elastin biosynthetic process" EXACT [] synonym: "down-regulation of elastin biosynthetic process" EXACT [] synonym: "downregulation of elastin biosynthetic process" EXACT [] synonym: "inhibition of elastin biosynthetic process" NARROW [] xref: GO:0051545 is_a: CCO:P0000984 ! negative regulation of glycoprotein biosynthetic process is_a: CCO:P0001135 ! negative regulation of translation is_a: CCO:P0003125 ! regulation of elastin biosynthetic process [Term] id: CCO:P0003128 name: regulation of keratinocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of keratinocyte migration." [GOC:ai] xref: GO:0051547 is_a: CCO:P0001257 ! regulation of cell migration [Term] id: CCO:P0003129 name: negative regulation of keratinocyte migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte migration." [GOC:ai] synonym: "down regulation of keratinocyte migration" EXACT [] synonym: "down-regulation of keratinocyte migration" EXACT [] synonym: "downregulation of keratinocyte migration" EXACT [] synonym: "inhibition of keratinocyte migration" NARROW [] xref: GO:0051548 is_a: CCO:P0001259 ! negative regulation of cell migration is_a: CCO:P0003128 ! regulation of keratinocyte migration [Term] id: CCO:P0003130 name: positive regulation of keratinocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of keratinocyte migration." [GOC:ai] synonym: "activation of keratinocyte migration" NARROW [] synonym: "stimulation of keratinocyte migration" NARROW [] synonym: "up regulation of keratinocyte migration" EXACT [] synonym: "up-regulation of keratinocyte migration" EXACT [] synonym: "upregulation of keratinocyte migration" EXACT [] xref: GO:0051549 is_a: CCO:P0001258 ! positive regulation of cell migration is_a: CCO:P0003128 ! regulation of keratinocyte migration relationship: has_participant CCO:B0021671 ! HBEGF_HUMAN [Term] id: CCO:P0003131 name: regulation of histone H3-K4 methylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3." [GOC:ai] xref: GO:0051569 is_a: CCO:P0001370 ! regulation of histone methylation [Term] id: CCO:P0003132 name: regulation of histone H3-K9 methylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3." [GOC:ai] xref: GO:0051570 is_a: CCO:P0001370 ! regulation of histone methylation [Term] id: CCO:P0003133 name: positive regulation of histone H3-K4 methylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3." [GOC:mah] synonym: "activation of histone H3-K4 methylation" NARROW [] synonym: "stimulation of histone H3-K4 methylation" NARROW [] synonym: "up regulation of histone H3-K4 methylation" EXACT [] synonym: "up-regulation of histone H3-K4 methylation" EXACT [] synonym: "upregulation of histone H3-K4 methylation" EXACT [] xref: GO:0051571 is_a: CCO:P0001372 ! positive regulation of histone methylation is_a: CCO:P0003131 ! regulation of histone H3-K4 methylation [Term] id: CCO:P0003134 name: negative regulation of histone H3-K4 methylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3." [GOC:mah] synonym: "down regulation of histone H3-K4 methylation" EXACT [] synonym: "down-regulation of histone H3-K4 methylation" EXACT [] synonym: "downregulation of histone H3-K4 methylation" EXACT [] synonym: "inhibition of histone H3-K4 methylation" NARROW [] xref: GO:0051572 is_a: CCO:P0001371 ! negative regulation of histone methylation is_a: CCO:P0003131 ! regulation of histone H3-K4 methylation [Term] id: CCO:P0003135 name: negative regulation of histone H3-K9 methylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3." [GOC:ai] synonym: "down regulation of histone H3-K9 methylation" EXACT [] synonym: "down-regulation of histone H3-K9 methylation" EXACT [] synonym: "downregulation of histone H3-K9 methylation" EXACT [] synonym: "inhibition of histone H3-K9 methylation" NARROW [] xref: GO:0051573 is_a: CCO:P0001371 ! negative regulation of histone methylation is_a: CCO:P0003132 ! regulation of histone H3-K9 methylation [Term] id: CCO:P0003136 name: positive regulation of histone H3-K9 methylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3." [GOC:ai] synonym: "activation of histone H3-K9 methylation" NARROW [] synonym: "stimulation of histone H3-K9 methylation" NARROW [] synonym: "up regulation of histone H3-K9 methylation" EXACT [] synonym: "up-regulation of histone H3-K9 methylation" EXACT [] synonym: "upregulation of histone H3-K9 methylation" EXACT [] xref: GO:0051574 is_a: CCO:P0001372 ! positive regulation of histone methylation is_a: CCO:P0003132 ! regulation of histone H3-K9 methylation [Term] id: CCO:P0003137 name: regulation of exocyst localization during endocytosis namespace: biological_process def: "Any process that modulates the localization of exocysts during endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where secretory vesicles dock and fuse." [GOC:ai] synonym: "regulation of site selection of endocytosis" RELATED [] synonym: "relocation of endocytosis" RELATED [] synonym: "spatial regulation of endocytosis" RELATED [] xref: GO:0051600 is_a: CCO:P0001243 ! regulation of endocytosis [Term] id: CCO:P0003138 name: barbed-end actin filament uncapping namespace: biological_process def: "The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits." [GOC:pf] synonym: "barbed end actin filament uncapping" EXACT [] synonym: "barbed end F-actin uncapping" EXACT [] synonym: "barbed-end F-actin uncapping" EXACT [] synonym: "plus end actin filament uncapping" EXACT [] synonym: "plus end F-actin uncapping" EXACT [] synonym: "plus-end actin filament uncapping" EXACT [] synonym: "plus-end F-actin uncapping" EXACT [] xref: GO:0051638 is_a: CCO:P0003141 ! actin filament uncapping [Term] id: CCO:P0003139 name: actin filament capping namespace: biological_process def: "The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X] synonym: "actin capping activity" RELATED [] synonym: "F-actin capping activity" RELATED [] xref: GO:0051693 is_a: CCO:P0001328 ! negative regulation of actin filament depolymerization [Term] id: CCO:P0003140 name: pointed-end actin filament capping namespace: biological_process def: "The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X] synonym: "minus-end actin filament capping activity" EXACT [] synonym: "minus-end F-actin capping activity" EXACT [] synonym: "pointed-end actin capping activity" EXACT [] synonym: "pointed-end F-actin capping activity" EXACT [] xref: GO:0051694 is_a: CCO:P0003139 ! actin filament capping [Term] id: CCO:P0003141 name: actin filament uncapping namespace: biological_process def: "The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits." [GOC:pf] synonym: "F-actin uncapping" EXACT [] xref: GO:0051695 is_a: CCO:P0001329 ! positive regulation of actin filament depolymerization [Term] id: CCO:P0003142 name: pointed-end actin filament uncapping namespace: biological_process def: "The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits." [GOC:pf] synonym: "minus end actin filament uncapping" EXACT [] synonym: "minus end F-actin uncapping" EXACT [] synonym: "minus-end actin filament uncapping" EXACT [] synonym: "minus-end F-actin uncapping" EXACT [] synonym: "pointed end actin filament uncapping" EXACT [] synonym: "pointed end F-actin uncapping" EXACT [] synonym: "pointed-end F-actin uncapping" EXACT [] xref: GO:0051696 is_a: CCO:P0003141 ! actin filament uncapping [Term] id: CCO:P0003143 name: positive regulation of cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai] synonym: "activation of cell division" NARROW [] synonym: "stimulation of cell division" NARROW [] synonym: "up regulation of cell division" EXACT [] synonym: "up-regulation of cell division" EXACT [] synonym: "upregulation of cell division" EXACT [] xref: GO:0051781 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003078 ! regulation of cell division relationship: positively_regulates CCO:P0003077 ! cell division [Term] id: CCO:P0003144 name: negative regulation of cell division namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell division." [GOC:ai] synonym: "down regulation of cell division" EXACT [] synonym: "down-regulation of cell division" EXACT [] synonym: "downregulation of cell division" EXACT [] synonym: "inhibition of cell division" NARROW [] xref: GO:0051782 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003078 ! regulation of cell division relationship: has_participant CCO:B0005502 ! BLM_HUMAN relationship: negatively_regulates CCO:P0003077 ! cell division [Term] id: CCO:P0003145 name: regulation of nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] xref: GO:0051783 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0003146 name: negative regulation of nuclear division namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "down regulation of nuclear division" EXACT [] synonym: "down-regulation of nuclear division" EXACT [] synonym: "downregulation of nuclear division" EXACT [] synonym: "inhibition of nuclear division" NARROW [] xref: GO:0051784 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003145 ! regulation of nuclear division [Term] id: CCO:P0003147 name: positive regulation of nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "activation of nuclear division" NARROW [] synonym: "stimulation of nuclear division" NARROW [] synonym: "up regulation of nuclear division" EXACT [] synonym: "up-regulation of nuclear division" EXACT [] synonym: "upregulation of nuclear division" EXACT [] xref: GO:0051785 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003145 ! regulation of nuclear division [Term] id: CCO:P0003148 name: regulation of synapse structural plasticity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane." [PMID:11063967, PMID:14976517, PMID:9884123] synonym: "regulation of synaptic structural plasticity" EXACT [] xref: GO:0051823 is_a: CCO:P0002961 ! regulation of synapse organization and biogenesis [Term] id: CCO:P0003149 name: negative regulation of synapse structural plasticity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse structural plasticity." [GOC:ai] synonym: "down regulation of synapse structural plasticity" EXACT [] synonym: "down-regulation of synapse structural plasticity" EXACT [] synonym: "downregulation of synapse structural plasticity" EXACT [] synonym: "inhibition of synapse structural plasticity" NARROW [] xref: GO:0051826 is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis is_a: CCO:P0003148 ! regulation of synapse structural plasticity [Term] id: CCO:P0003150 name: positive regulation of synapse structural plasticity namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity." [GOC:ai] synonym: "activation of synapse structural plasticity" NARROW [] synonym: "stimulation of synapse structural plasticity" NARROW [] synonym: "up regulation of synapse structural plasticity" EXACT [] synonym: "up-regulation of synapse structural plasticity" EXACT [] synonym: "upregulation of synapse structural plasticity" EXACT [] xref: GO:0051835 is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis is_a: CCO:P0003148 ! regulation of synapse structural plasticity [Term] id: CCO:P0003151 name: regulation of cardioblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast." [GOC:ai] xref: GO:0051890 is_a: CCO:P0002409 ! regulation of cell differentiation [Term] id: CCO:P0003152 name: positive regulation of cardioblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast." [GOC:ai] synonym: "activation of cardioblast differentiation" NARROW [] synonym: "stimulation of cardioblast differentiation" NARROW [] synonym: "up regulation of cardioblast differentiation" EXACT [] synonym: "up-regulation of cardioblast differentiation" EXACT [] synonym: "upregulation of cardioblast differentiation" EXACT [] xref: GO:0051891 is_a: CCO:P0002411 ! positive regulation of cell differentiation is_a: CCO:P0003151 ! regulation of cardioblast differentiation relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0058429 ! TBX5_HUMAN [Term] id: CCO:P0003153 name: negative regulation of cardioblast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast differentiation, the process whereby a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast." [GOC:ai] synonym: "down regulation of cardioblast differentiation" EXACT [] synonym: "down-regulation of cardioblast differentiation" EXACT [] synonym: "downregulation of cardioblast differentiation" EXACT [] synonym: "inhibition of cardioblast differentiation" NARROW [] xref: GO:0051892 is_a: CCO:P0002410 ! negative regulation of cell differentiation is_a: CCO:P0003151 ! regulation of cardioblast differentiation [Term] id: CCO:P0003154 name: regulation of focal adhesion formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions." [GOC:ai] xref: GO:0051893 is_a: CCO:P0000507 ! regulation of cell-matrix adhesion [Term] id: CCO:P0003155 name: positive regulation of focal adhesion formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions." [GOC:ai] synonym: "activation of focal adhesion formation" NARROW [] synonym: "stimulation of focal adhesion formation" NARROW [] synonym: "up regulation of focal adhesion formation" EXACT [] synonym: "up-regulation of focal adhesion formation" EXACT [] synonym: "upregulation of focal adhesion formation" EXACT [] xref: GO:0051894 is_a: CCO:P0000509 ! positive regulation of cell-matrix adhesion is_a: CCO:P0003154 ! regulation of focal adhesion formation relationship: has_participant CCO:B0002014 ! TSC1_HUMAN [Term] id: CCO:P0003156 name: negative regulation of focal adhesion formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions." [GOC:ai] synonym: "down regulation of focal adhesion formation" EXACT [] synonym: "down-regulation of focal adhesion formation" EXACT [] synonym: "downregulation of focal adhesion formation" EXACT [] synonym: "inhibition of focal adhesion formation" NARROW [] xref: GO:0051895 is_a: CCO:P0000508 ! negative regulation of cell-matrix adhesion is_a: CCO:P0003154 ! regulation of focal adhesion formation relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: has_participant CCO:B0020366 ! ACVL1_HUMAN relationship: has_participant CCO:B0055446 ! MMP14_HUMAN [Term] id: CCO:P0003157 name: regulation of protein kinase B signaling cascade namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B." [GOC:ai] synonym: "regulation of AKT signaling cascade" EXACT [] synonym: "regulation of AKT signalling cascade" EXACT [] synonym: "regulation of PKB signaling cascade" EXACT [] synonym: "regulation of PKB signalling cascade" EXACT [] synonym: "regulation of protein kinase B signalling cascade" EXACT [] xref: GO:0051896 is_a: CCO:P0001017 ! regulation of protein kinase cascade relationship: has_participant CCO:B0048930 ! RICTR_HUMAN relationship: regulates CCO:P0002225 ! protein kinase B signaling cascade [Term] id: CCO:P0003158 name: positive regulation of protein kinase B signaling cascade namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B." [GOC:ai] synonym: "activation of protein kinase B signaling cascade" NARROW [] synonym: "positive regulation of AKT signaling cascade" EXACT [] synonym: "positive regulation of AKT signalling cascade" EXACT [] synonym: "positive regulation of PKB signaling cascade" EXACT [] synonym: "positive regulation of PKB signalling cascade" EXACT [] synonym: "positive regulation of protein kinase B signalling cascade" EXACT [] synonym: "stimulation of protein kinase B signaling cascade" NARROW [] synonym: "up regulation of protein kinase B signaling cascade" EXACT [] synonym: "up-regulation of protein kinase B signaling cascade" EXACT [] synonym: "upregulation of protein kinase B signaling cascade" EXACT [] xref: GO:0051897 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0003157 ! regulation of protein kinase B signaling cascade relationship: positively_regulates CCO:P0002225 ! protein kinase B signaling cascade [Term] id: CCO:P0003159 name: negative regulation of protein kinase B signaling cascade namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B." [GOC:ai] synonym: "down regulation of protein kinase B signaling cascade" EXACT [] synonym: "down-regulation of protein kinase B signaling cascade" EXACT [] synonym: "downregulation of protein kinase B signaling cascade" EXACT [] synonym: "inhibition of protein kinase B signaling cascade" NARROW [] synonym: "negative regulation of AKT signaling cascade" EXACT [] synonym: "negative regulation of AKT signalling cascade" EXACT [] synonym: "negative regulation of PKB signaling cascade" EXACT [] synonym: "negative regulation of PKB signalling cascade" EXACT [] synonym: "negative regulation of protein kinase B signalling cascade" EXACT [] xref: GO:0051898 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0003157 ! regulation of protein kinase B signaling cascade relationship: has_participant CCO:B0001637 ! TSC2_HUMAN relationship: has_participant CCO:B0001685 ! PTEN_HUMAN relationship: negatively_regulates CCO:P0002225 ! protein kinase B signaling cascade [Term] id: CCO:P0003160 name: regulation of mitochondrial depolarization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive." [GOC:ai] xref: GO:0051900 is_a: CCO:P0002955 ! regulation of cellular process relationship: has_participant CCO:B0055404 ! GSH1_HUMAN relationship: has_participant CCO:B0055405 ! GSH0_HUMAN [Term] id: CCO:P0003161 name: positive regulation of mitochondrial depolarization namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive." [GOC:ai] synonym: "activation of mitochondrial depolarization" NARROW [] synonym: "stimulation of mitochondrial depolarization" NARROW [] synonym: "up regulation of mitochondrial depolarization" EXACT [] synonym: "up-regulation of mitochondrial depolarization" EXACT [] synonym: "upregulation of mitochondrial depolarization" EXACT [] xref: GO:0051901 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003160 ! regulation of mitochondrial depolarization [Term] id: CCO:P0003162 name: negative regulation of mitochondrial depolarization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive." [GOC:ai] synonym: "down regulation of mitochondrial depolarization" EXACT [] synonym: "down-regulation of mitochondrial depolarization" EXACT [] synonym: "downregulation of mitochondrial depolarization" EXACT [] synonym: "inhibition of mitochondrial depolarization" NARROW [] xref: GO:0051902 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003160 ! regulation of mitochondrial depolarization relationship: has_participant CCO:B0001506 ! BCL2_HUMAN relationship: has_participant CCO:B0054951 ! IFI6_HUMAN [Term] id: CCO:P0003163 name: regulation of synaptic plasticity by chemical substance namespace: biological_process def: "The process by which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require." [GOC:ai] synonym: "regulation of synaptic plasticity by drug" NARROW [] xref: GO:0051913 is_a: CCO:P0002784 ! regulation of synaptic plasticity [Term] id: CCO:P0003164 name: positive regulation of synaptic plasticity by chemical substance namespace: biological_process def: "The process by which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require." [GOC:ai] synonym: "activation of synaptic plasticity by chemical substance" NARROW [] synonym: "positive regulation of synaptic plasticity by drug" NARROW [] synonym: "stimulation of synaptic plasticity by chemical substance" NARROW [] synonym: "up regulation of synaptic plasticity by chemical substance" EXACT [] synonym: "up-regulation of synaptic plasticity by chemical substance" EXACT [] synonym: "upregulation of synaptic plasticity by chemical substance" EXACT [] xref: GO:0051914 is_a: CCO:P0001491 ! positive regulation of synaptic plasticity is_a: CCO:P0003163 ! regulation of synaptic plasticity by chemical substance [Term] id: CCO:P0003165 name: induction of synaptic plasticity by chemical substance namespace: biological_process def: "The process by which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require." [GOC:ai] synonym: "activation of synaptic plasticity by chemical substance" EXACT [] synonym: "activation of synaptic plasticity by drug" NARROW [] synonym: "induction of synaptic plasticity by drug" NARROW [] xref: GO:0051915 is_a: CCO:P0003164 ! positive regulation of synaptic plasticity by chemical substance [Term] id: CCO:P0003166 name: regulation of synaptogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synaptogenesis, the formation of a synapse." [GOC:ai] xref: GO:0051963 is_a: CCO:P0002961 ! regulation of synapse organization and biogenesis relationship: has_participant CCO:B0032807 ! ACHB2_HUMAN relationship: has_participant CCO:B0058105 ! GHSR_HUMAN [Term] id: CCO:P0003167 name: negative regulation of synaptogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synaptogenesis, the formation of a synapse." [GOC:ai] synonym: "down regulation of synaptogenesis" EXACT [] synonym: "down-regulation of synaptogenesis" EXACT [] synonym: "downregulation of synaptogenesis" EXACT [] synonym: "inhibition of synaptogenesis" NARROW [] xref: GO:0051964 is_a: CCO:P0003033 ! negative regulation of cellular component organization and biogenesis is_a: CCO:P0003166 ! regulation of synaptogenesis [Term] id: CCO:P0003168 name: positive regulation of synaptogenesis namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of synaptogenesis, the formation of a synapse." [GOC:ai] synonym: "activation of synaptogenesis" NARROW [] synonym: "stimulation of synaptogenesis" NARROW [] synonym: "up regulation of synaptogenesis" EXACT [] synonym: "up-regulation of synaptogenesis" EXACT [] synonym: "upregulation of synaptogenesis" EXACT [] xref: GO:0051965 is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis is_a: CCO:P0003166 ! regulation of synaptogenesis relationship: has_participant CCO:B0033567 ! GHRL_HUMAN relationship: has_participant CCO:B0054341 ! WNT7A_HUMAN [Term] id: CCO:P0003169 name: regulation of synaptic transmission, glutamatergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." [GOC:ai] xref: GO:0051966 is_a: CCO:P0002958 ! regulation of synaptic transmission relationship: has_participant CCO:B0020614 ! GRIK1_HUMAN [Term] id: CCO:P0003170 name: negative regulation of synaptic transmission, glutamatergic namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." [GOC:ai] synonym: "down regulation of synaptic transmission, glutamatergic" EXACT [] synonym: "down-regulation of synaptic transmission, glutamatergic" EXACT [] synonym: "downregulation of synaptic transmission, glutamatergic" EXACT [] synonym: "inhibition of synaptic transmission, glutamatergic" NARROW [] xref: GO:0051967 is_a: CCO:P0002959 ! negative regulation of synaptic transmission is_a: CCO:P0003169 ! regulation of synaptic transmission, glutamatergic relationship: has_participant CCO:B0055198 ! 5HT2A_HUMAN [Term] id: CCO:P0003171 name: positive regulation of synaptic transmission, glutamatergic namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate." [GOC:ai] synonym: "activation of synaptic transmission, glutamatergic" NARROW [] synonym: "stimulation of synaptic transmission, glutamatergic" NARROW [] synonym: "up regulation of synaptic transmission, glutamatergic" EXACT [] synonym: "up-regulation of synaptic transmission, glutamatergic" EXACT [] synonym: "upregulation of synaptic transmission, glutamatergic" EXACT [] xref: GO:0051968 is_a: CCO:P0002960 ! positive regulation of synaptic transmission is_a: CCO:P0003169 ! regulation of synaptic transmission, glutamatergic [Term] id: CCO:P0003172 name: regulation of transmission of nerve impulse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] xref: GO:0051969 is_a: CCO:P0002955 ! regulation of cellular process [Term] id: CCO:P0003173 name: negative regulation of transmission of nerve impulse namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "down regulation of transmission of nerve impulse" EXACT [] synonym: "down-regulation of transmission of nerve impulse" EXACT [] synonym: "downregulation of transmission of nerve impulse" EXACT [] synonym: "inhibition of transmission of nerve impulse" NARROW [] xref: GO:0051970 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003172 ! regulation of transmission of nerve impulse relationship: has_participant CCO:B0022913 ! GLRA1_HUMAN [Term] id: CCO:P0003174 name: positive regulation of transmission of nerve impulse namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "activation of transmission of nerve impulse" NARROW [] synonym: "stimulation of transmission of nerve impulse" NARROW [] synonym: "up regulation of transmission of nerve impulse" EXACT [] synonym: "up-regulation of transmission of nerve impulse" EXACT [] synonym: "upregulation of transmission of nerve impulse" EXACT [] xref: GO:0051971 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003172 ! regulation of transmission of nerve impulse relationship: has_participant CCO:B0056152 ! CART_HUMAN [Term] id: CCO:P0003175 name: regulation of chromosome segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chromosome segregation, the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] xref: GO:0051983 is_a: CCO:P0002955 ! regulation of cellular process relationship: regulates CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0003176 name: positive regulation of chromosome segregation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "activation of chromosome segregation" NARROW [] synonym: "stimulation of chromosome segregation" NARROW [] synonym: "up regulation of chromosome segregation" EXACT [] synonym: "up-regulation of chromosome segregation" EXACT [] synonym: "upregulation of chromosome segregation" EXACT [] xref: GO:0051984 is_a: CCO:P0002852 ! positive regulation of cellular process is_a: CCO:P0003175 ! regulation of chromosome segregation relationship: positively_regulates CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0003177 name: negative regulation of chromosome segregation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome segregation, the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "down regulation of chromosome segregation" EXACT [] synonym: "down-regulation of chromosome segregation" EXACT [] synonym: "downregulation of chromosome segregation" EXACT [] synonym: "inhibition of chromosome segregation" NARROW [] xref: GO:0051985 is_a: CCO:P0002853 ! negative regulation of cellular process is_a: CCO:P0003175 ! regulation of chromosome segregation relationship: negatively_regulates CCO:P0000695 ! chromosome segregation [Term] id: CCO:P0003178 name: negative regulation of attachment of spindle microtubules to kinetochore namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore." [GOC:ai] synonym: "down regulation of attachment of spindle microtubules to kinetochore" EXACT [] synonym: "down-regulation of attachment of spindle microtubules to kinetochore" EXACT [] synonym: "downregulation of attachment of spindle microtubules to kinetochore" EXACT [] synonym: "inhibition of attachment of spindle microtubules to kinetochore" NARROW [] xref: GO:0051986 is_a: CCO:P0003106 ! negative regulation of cytoskeleton organization and biogenesis is_a: CCO:P0003177 ! negative regulation of chromosome segregation is_a: CCO:P0003180 ! regulation of attachment of spindle microtubules to kinetochore relationship: negatively_regulates CCO:P0000830 ! attachment of spindle microtubules to kinetochore [Term] id: CCO:P0003179 name: positive regulation of attachment of spindle microtubules to kinetochore namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore." [GOC:ai] synonym: "activation of attachment of spindle microtubules to kinetochore" NARROW [] synonym: "stimulation of attachment of spindle microtubules to kinetochore" NARROW [] synonym: "up regulation of attachment of spindle microtubules to kinetochore" EXACT [] synonym: "up-regulation of attachment of spindle microtubules to kinetochore" EXACT [] synonym: "upregulation of attachment of spindle microtubules to kinetochore" EXACT [] xref: GO:0051987 is_a: CCO:P0003107 ! positive regulation of cytoskeleton organization and biogenesis is_a: CCO:P0003176 ! positive regulation of chromosome segregation is_a: CCO:P0003180 ! regulation of attachment of spindle microtubules to kinetochore relationship: positively_regulates CCO:P0000830 ! attachment of spindle microtubules to kinetochore [Term] id: CCO:P0003180 name: regulation of attachment of spindle microtubules to kinetochore namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore." [GOC:ai] xref: GO:0051988 is_a: CCO:P0001703 ! regulation of microtubule-based process is_a: CCO:P0003175 ! regulation of chromosome segregation relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: regulates CCO:P0000830 ! attachment of spindle microtubules to kinetochore [Term] id: CCO:P0003181 name: modulation by symbiont of host transcription namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of host transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok xref: GO:0052026 is_a: CCO:P0003197 ! modulation of transcription in other organism during symbiotic interaction [Term] id: CCO:P0003182 name: induction by symbiont of host apoptosis namespace: biological_process def: "Any process by which an organism activates programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of host apoptosis" EXACT [] synonym: "activation by organism of host apoptotic programmed cell death" EXACT [] synonym: "induction by organism of host apoptotic programmed cell death" EXACT [] xref: GO:0052030 is_a: CCO:P0003186 ! induction by symbiont of host programmed cell death is_a: CCO:P0003190 ! positive regulation by symbiont of host apoptosis is_a: CCO:P0003206 ! induction by organism of apoptosis in other organism during symbiotic interaction [Term] id: CCO:P0003183 name: modulation by symbiont of host programmed cell death namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "modulation of host PCD" EXACT [] xref: GO:0052040 is_a: CCO:P0003196 ! modulation of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003184 name: negative regulation by symbiont of host programmed cell death namespace: biological_process def: "Any process by which an organism stops, prevents or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "down regulation by symbiont of host programmed cell death" EXACT [] synonym: "down-regulation by symbiont of host programmed cell death" EXACT [] synonym: "downregulation by symbiont of host programmed cell death" EXACT [] synonym: "inhibition by symbiont of host programmed cell death" NARROW [] synonym: "inhibition of host programmed cell death" EXACT [] synonym: "suppression by symbiont of host PCD" EXACT [] synonym: "suppression by symbiont of host programmed cell death" EXACT [] xref: GO:0052041 is_a: CCO:P0003183 ! modulation by symbiont of host programmed cell death is_a: CCO:P0003214 ! negative regulation by organism of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003185 name: positive regulation by symbiont of host programmed cell death namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by symbiont of host programmed cell death" NARROW [] synonym: "enhancement of host programmed cell death" EXACT [] synonym: "stimulation by symbiont of host programmed cell death" NARROW [] xref: GO:0052042 is_a: CCO:P0003183 ! modulation by symbiont of host programmed cell death is_a: CCO:P0003204 ! positive regulation by organism of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003186 name: induction by symbiont of host programmed cell death namespace: biological_process def: "The activation by an organism of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of host programmed cell death" EXACT [] xref: GO:0052044 is_a: CCO:P0003185 ! positive regulation by symbiont of host programmed cell death is_a: CCO:P0003208 ! induction by organism of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003187 name: upregulation by symbiont of host programmed cell death namespace: biological_process def: "Any process by which an organism increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "enhancement of host programmed cell death by organism" EXACT [] xref: GO:0052045 is_a: CCO:P0003185 ! positive regulation by symbiont of host programmed cell death is_a: CCO:P0003219 ! upregulation by organism of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003188 name: entry of symbiont into host cell by promotion of host phagocytosis namespace: biological_process def: "The invasion by an organism of a cell of its host organism by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] synonym: "entry of organism into host cell by promotion of host phagocytosis" EXACT [] xref: GO:0052066 is_a: CCO:P0003194 ! positive regulation by symbiont of host phagocytosis is_a: CCO:P0003205 ! entry of organism into cell of other organism by promotion of phagocytosis in other organism during symbiotic interaction [Term] id: CCO:P0003189 name: modulation by symbiont of host apoptosis namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] comment: Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'regulation of apoptosis ; GO:0042981'. subset: gosubset_prok synonym: "modulation by organism of host apoptotic programmed cell death" EXACT [] xref: GO:0052150 is_a: CCO:P0003183 ! modulation by symbiont of host programmed cell death is_a: CCO:P0003209 ! modulation by organism of apoptosis in other organism during symbiotic interaction [Term] id: CCO:P0003190 name: positive regulation by symbiont of host apoptosis namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] comment: Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'positive regulation of apoptosis ; GO:0043065'. subset: gosubset_prok synonym: "activation by symbiont of host apoptosis" NARROW [] synonym: "positive regulation by organism of host apoptotic programmed cell death" EXACT [] synonym: "stimulation by symbiont of host apoptosis" NARROW [] synonym: "up regulation by organism of host apoptotic programmed cell death" EXACT [] synonym: "up regulation by symbiont of host apoptosis" EXACT [] synonym: "up-regulation by organism of host apoptotic programmed cell death" EXACT [] synonym: "up-regulation by symbiont of host apoptosis" EXACT [] synonym: "upregulation by organism of host apoptotic programmed cell death" EXACT [] synonym: "upregulation by symbiont of host apoptosis" EXACT [] xref: GO:0033669 xref: GO:0052151 is_a: CCO:P0003185 ! positive regulation by symbiont of host programmed cell death is_a: CCO:P0003189 ! modulation by symbiont of host apoptosis is_a: CCO:P0003215 ! positive regulation by organism of apoptosis in other organism during symbiotic interaction [Term] id: CCO:P0003191 name: modulation by symbiont of host non-apoptotic programmed cell death namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by a non-apoptotic pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok xref: GO:0052152 is_a: CCO:P0003183 ! modulation by symbiont of host programmed cell death is_a: CCO:P0003210 ! modulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003192 name: positive regulation by symbiont of host non-apoptotic programmed cell death namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by a non-apoptotic pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by symbiont of host non-apoptotic programmed cell death" NARROW [] synonym: "stimulation by symbiont of host non-apoptotic programmed cell death" NARROW [] synonym: "up regulation by symbiont of host non-apoptotic programmed cell death" EXACT [] synonym: "up-regulation by symbiont of host non-apoptotic programmed cell death" EXACT [] synonym: "upregulation by symbiont of host non-apoptotic programmed cell death" EXACT [] xref: GO:0052153 is_a: CCO:P0003185 ! positive regulation by symbiont of host programmed cell death is_a: CCO:P0003191 ! modulation by symbiont of host non-apoptotic programmed cell death is_a: CCO:P0003216 ! positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003193 name: modulation by symbiont of host phagocytosis namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] xref: GO:0052190 is_a: CCO:P0003195 ! modulation of phagocytosis in other organism during symbiotic interaction [Term] id: CCO:P0003194 name: positive regulation by symbiont of host phagocytosis namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] synonym: "activation by symbiont of host phagocytosis" NARROW [] synonym: "stimulation by symbiont of host phagocytosis" NARROW [] synonym: "up regulation by symbiont of host phagocytosis" EXACT [] synonym: "up-regulation by symbiont of host phagocytosis" EXACT [] synonym: "upregulation by symbiont of host phagocytosis" EXACT [] xref: GO:0052191 is_a: CCO:P0003193 ! modulation by symbiont of host phagocytosis is_a: CCO:P0003218 ! positive regulation by organism of phagocytosis in other organism during symbiotic interaction [Term] id: CCO:P0003195 name: modulation of phagocytosis in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] xref: GO:0052231 is_a: CCO:P0002942 ! regulation of phagocytosis [Term] id: CCO:P0003196 name: modulation of programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok xref: GO:0052248 is_a: CCO:P0002149 ! regulation of programmed cell death [Term] id: CCO:P0003197 name: modulation of transcription in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA, in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok xref: GO:0052312 is_a: CCO:P0002369 ! regulation of transcription [Term] id: CCO:P0003198 name: regulation of phytoalexin metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response." [GOC:ai] synonym: "regulation of phytoalexin metabolism" EXACT [] xref: GO:0052318 is_a: CCO:P0001404 ! regulation of cellular metabolic process [Term] id: CCO:P0003199 name: regulation of phytoalexin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins." [GOC:ai] synonym: "regulation of phytoalexin biosynthesis" EXACT [] xref: GO:0052319 is_a: CCO:P0001407 ! regulation of cellular biosynthetic process is_a: CCO:P0003198 ! regulation of phytoalexin metabolic process [Term] id: CCO:P0003200 name: positive regulation of phytoalexin metabolic process namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins." [GOC:mtg_pamgo_17jul06] synonym: "activation of phytoalexin metabolism" NARROW [] synonym: "positive regulation of phytoalexin metabolism" RELATED [] synonym: "stimulation of phytoalexin metabolism" NARROW [] synonym: "up regulation of phytoalexin metabolism" EXACT [] synonym: "up-regulation of phytoalexin metabolism" EXACT [] synonym: "upregulation of phytoalexin metabolism" EXACT [] xref: GO:0052320 is_a: CCO:P0001406 ! positive regulation of cellular metabolic process is_a: CCO:P0003198 ! regulation of phytoalexin metabolic process [Term] id: CCO:P0003201 name: negative regulation of phytoalexin metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins." [GOC:ai] synonym: "down regulation of phytoalexin metabolism" EXACT [] synonym: "down-regulation of phytoalexin metabolism" EXACT [] synonym: "downregulation of phytoalexin metabolism" EXACT [] synonym: "inhibition of phytoalexin metabolism" NARROW [] synonym: "negative regulation of phytoalexin metabolism" EXACT [] xref: GO:0052321 is_a: CCO:P0001405 ! negative regulation of cellular metabolic process is_a: CCO:P0003198 ! regulation of phytoalexin metabolic process [Term] id: CCO:P0003202 name: positive regulation of phytoalexin biosynthetic process namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins." [GOC:mtg_pamgo_17jul06] synonym: "activation of phytoalexin biosynthesis" NARROW [] synonym: "positive regulation of phytoalexin biosynthesis" EXACT [] synonym: "stimulation of phytoalexin biosynthesis" NARROW [] synonym: "up regulation of phytoalexin biosynthesis" EXACT [] synonym: "up-regulation of phytoalexin biosynthesis" EXACT [] synonym: "upregulation of phytoalexin biosynthesis" EXACT [] xref: GO:0052322 is_a: CCO:P0001409 ! positive regulation of cellular biosynthetic process is_a: CCO:P0003199 ! regulation of phytoalexin biosynthetic process is_a: CCO:P0003200 ! positive regulation of phytoalexin metabolic process [Term] id: CCO:P0003203 name: negative regulation of phytoalexin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins." [GOC:ai] synonym: "down regulation of phytoalexin biosynthesis" EXACT [] synonym: "down-regulation of phytoalexin biosynthesis" EXACT [] synonym: "downregulation of phytoalexin biosynthesis" EXACT [] synonym: "inhibition of phytoalexin biosynthesis" NARROW [] synonym: "negative regulation of phytoalexin biosynthesis" EXACT [] xref: GO:0052323 is_a: CCO:P0001408 ! negative regulation of cellular biosynthetic process is_a: CCO:P0003199 ! regulation of phytoalexin biosynthetic process is_a: CCO:P0003201 ! negative regulation of phytoalexin metabolic process [Term] id: CCO:P0003204 name: positive regulation by organism of programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of programmed cell death in other organism during symbiotic interaction" NARROW [] synonym: "stimulation by organism of programmed cell death in other organism during symbiotic interaction" NARROW [] xref: GO:0052330 is_a: CCO:P0003196 ! modulation of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003205 name: entry of organism into cell of other organism by promotion of phagocytosis in other organism during symbiotic interaction namespace: biological_process def: "The invasion by an organism of a cell of a second organism by utilizing the second organism's phagocytosis mechanism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] xref: GO:0052370 is_a: CCO:P0003218 ! positive regulation by organism of phagocytosis in other organism during symbiotic interaction [Term] id: CCO:P0003206 name: induction by organism of apoptosis in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism activates programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of apoptosis in other organism during symbiotic interaction" EXACT [] synonym: "activation by organism of apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] synonym: "induction by organism of apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] xref: GO:0052388 is_a: CCO:P0003208 ! induction by organism of programmed cell death in other organism during symbiotic interaction is_a: CCO:P0003215 ! positive regulation by organism of apoptosis in other organism during symbiotic interaction [Term] id: CCO:P0003207 name: induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism activates programmed cell death by a non-apoptotic pathway in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of non-apoptotic programmed cell death in other organism" EXACT [] xref: GO:0052397 is_a: CCO:P0003208 ! induction by organism of programmed cell death in other organism during symbiotic interaction is_a: CCO:P0003216 ! positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003208 name: induction by organism of programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "The activation by an organism of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of programmed cell death in other organism during symbiotic interaction" EXACT [] xref: GO:0052400 is_a: CCO:P0003204 ! positive regulation by organism of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003209 name: modulation by organism of apoptosis in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "modulation by organism of apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] xref: GO:0052433 is_a: CCO:P0002131 ! regulation of apoptosis is_a: CCO:P0003196 ! modulation of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003210 name: modulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of programmed cell death by a non-apoptotic pathway in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok xref: GO:0052459 is_a: CCO:P0002152 ! regulation of non-apoptotic programmed cell death is_a: CCO:P0003196 ! modulation of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003211 name: modulation by host of symbiont phagocytosis namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] xref: GO:0052462 is_a: CCO:P0003195 ! modulation of phagocytosis in other organism during symbiotic interaction [Term] id: CCO:P0003212 name: modulation by host of symbiont transcription namespace: biological_process def: "Any process by which an organism modulates the frequency, rate or extent of symbiont transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] xref: GO:0052472 is_a: CCO:P0003197 ! modulation of transcription in other organism during symbiotic interaction [Term] id: CCO:P0003213 name: negative regulation by host of symbiont programmed cell death namespace: biological_process def: "Any process by which an organism stops, prevents or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "down regulation by host of symbiont programmed cell death" EXACT [] synonym: "down-regulation by host of symbiont programmed cell death" EXACT [] synonym: "downregulation by host of symbiont programmed cell death" EXACT [] synonym: "inhibition by host of symbiont programmed cell death" NARROW [] synonym: "inhibition of symbiont programmed cell death" EXACT [] xref: GO:0052489 is_a: CCO:P0003214 ! negative regulation by organism of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003214 name: negative regulation by organism of programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism stops, prevents or reduces the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "down regulation by organism of programmed cell death in other organism during symbiotic interaction" EXACT [] synonym: "down-regulation by organism of programmed cell death in other organism during symbiotic interaction" EXACT [] synonym: "downregulation by organism of programmed cell death in other organism during symbiotic interaction" EXACT [] synonym: "inhibition by organism of programmed cell death in other organism during symbiotic interaction" NARROW [] synonym: "inhibition of programmed cell death in other organism" EXACT [] xref: GO:0052490 is_a: CCO:P0002151 ! negative regulation of programmed cell death is_a: CCO:P0003196 ! modulation of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003215 name: positive regulation by organism of apoptosis in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of apoptosis in other organism during symbiotic interaction" NARROW [] synonym: "positive regulation by organism of apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] synonym: "stimulation by organism of apoptosis in other organism during symbiotic interaction" NARROW [] synonym: "up regulation by organism of apoptosis in other organism during symbiotic interaction" EXACT [] synonym: "up-regulation by organism of apoptosis in other organism during symbiotic interaction" EXACT [] synonym: "upregulation by organism of apoptosis in other organism during symbiotic interaction" EXACT [] xref: GO:0052501 is_a: CCO:P0002147 ! positive regulation of apoptosis is_a: CCO:P0003204 ! positive regulation by organism of programmed cell death in other organism during symbiotic interaction is_a: CCO:P0003209 ! modulation by organism of apoptosis in other organism during symbiotic interaction [Term] id: CCO:P0003216 name: positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by a non-apoptotic pathway in the second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "activation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" NARROW [] synonym: "stimulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" NARROW [] synonym: "up regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] synonym: "up-regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] synonym: "upregulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction" EXACT [] xref: GO:0052518 is_a: CCO:P0002153 ! positive regulation of non-apoptotic programmed cell death is_a: CCO:P0003204 ! positive regulation by organism of programmed cell death in other organism during symbiotic interaction is_a: CCO:P0003210 ! modulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003217 name: positive regulation by host of symbiont phagocytosis namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] synonym: "activation by host of symbiont phagocytosis" NARROW [] synonym: "stimulation by host of symbiont phagocytosis" NARROW [] synonym: "up regulation by host of symbiont phagocytosis" EXACT [] synonym: "up-regulation by host of symbiont phagocytosis" EXACT [] synonym: "upregulation by host of symbiont phagocytosis" EXACT [] xref: GO:0052521 is_a: CCO:P0003211 ! modulation by host of symbiont phagocytosis is_a: CCO:P0003218 ! positive regulation by organism of phagocytosis in other organism during symbiotic interaction [Term] id: CCO:P0003218 name: positive regulation by organism of phagocytosis in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] synonym: "activation by organism of phagocytosis in other organism during symbiotic interaction" NARROW [] synonym: "stimulation by organism of phagocytosis in other organism during symbiotic interaction" NARROW [] synonym: "up regulation by organism of phagocytosis in other organism during symbiotic interaction" EXACT [] synonym: "up-regulation by organism of phagocytosis in other organism during symbiotic interaction" EXACT [] synonym: "upregulation by organism of phagocytosis in other organism during symbiotic interaction" EXACT [] xref: GO:0052522 is_a: CCO:P0002944 ! positive regulation of phagocytosis is_a: CCO:P0003195 ! modulation of phagocytosis in other organism during symbiotic interaction [Term] id: CCO:P0003219 name: upregulation by organism of programmed cell death in other organism during symbiotic interaction namespace: biological_process def: "Any process by which an organism increases the frequency, rate or extent of programmed cell death in the second organism, where the two organisms are in a symbiotic interaction." [GOC:mtg_pamgo_17jul06] subset: gosubset_prok synonym: "enhancement of other organism programmed cell death by organism" EXACT [] xref: GO:0052529 is_a: CCO:P0003204 ! positive regulation by organism of programmed cell death in other organism during symbiotic interaction [Term] id: CCO:P0003220 name: neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167] synonym: "neuroblast cell division" EXACT [] xref: GO:0055057 is_a: CCO:P0003077 ! cell division relationship: part_of CCO:P0000793 ! neuroblast proliferation [Term] id: CCO:P0003221 name: symmetric neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells." [GOC:dph] xref: GO:0055058 is_a: CCO:P0003220 ! neuroblast division [Term] id: CCO:P0003222 name: asymmetric neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph] xref: GO:0055059 is_a: CCO:P0003220 ! neuroblast division [Term] id: CCO:P0003223 name: asymmetric neuroblast division resulting in ganglion mother cell formation namespace: biological_process def: "Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell." [GOC:dph] xref: GO:0055060 is_a: CCO:P0003222 ! asymmetric neuroblast division [Term] id: CCO:P0003224 name: lipoprotein mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of lipoprotein." [GOC:rl] synonym: "lipoprotein mediated signalling " EXACT [] xref: GO:0055095 is_a: CCO:P0000766 ! intracellular signaling cascade [Term] id: CCO:P0003225 name: low density lipoprotein mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of low density lipoprotein." [GOC:rl] synonym: "low density lipoprotein mediated signalling" EXACT [] xref: GO:0055096 is_a: CCO:P0003224 ! lipoprotein mediated signaling relationship: has_participant CCO:B0055534 ! CAD13_HUMAN [Term] id: CCO:P0003226 name: high density lipoprotein mediated signaling namespace: biological_process def: "A series of molecular signals mediated by the detection of high density lipoprotein." [GOC:rl] synonym: "high density lipoprotein mediated signalling" EXACT [] xref: GO:0055097 is_a: CCO:P0003224 ! lipoprotein mediated signaling [Term] id: CCO:P0003227 name: delamination involved in gastrulation with mouth forming second namespace: biological_process def: "The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation." [ISBN:0878932437] xref: GO:0055112 is_a: CCO:P0003288 ! delamination [Term] id: CCO:P0003228 name: Sertoli cell proliferation namespace: biological_process def: "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] xref: GO:0060011 is_a: CCO:P0000815 ! cell proliferation relationship: has_participant CCO:B0005543 ! AVR2A_HUMAN relationship: has_participant CCO:B0054839 ! FSHB_HUMAN [Term] id: CCO:P0003229 name: rhythmic synaptic transmission namespace: biological_process def: "Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit." [GOC:dph] xref: GO:0060024 is_a: CCO:P0002958 ! regulation of synaptic transmission [Term] id: CCO:P0003230 name: regulation of synaptic activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell." [GOC:dph, GOC:tb] xref: GO:0060025 is_a: CCO:P0002958 ! regulation of synaptic transmission [Term] id: CCO:P0003231 name: cardiac muscle cell proliferation namespace: biological_process def: "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rh1, PMID:11161571] synonym: "cardiac myocyte proliferation" EXACT [] synonym: "cardiomyocyte proliferation" RELATED [GOC:dph, PMID:10074473] synonym: "heart muscle cell proliferation" EXACT [] xref: GO:0060038 is_a: CCO:P0001098 ! striated muscle cell proliferation relationship: has_participant CCO:B0001687 ! TGFB2_HUMAN relationship: has_participant CCO:B0001735 ! FOXC1_HUMAN relationship: has_participant CCO:B0016732 ! FOXC2_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN [Term] id: CCO:P0003232 name: regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rh] synonym: "regulation of heart muscle cell proliferation" EXACT [] xref: GO:0060043 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0003231 ! cardiac muscle cell proliferation [Term] id: CCO:P0003233 name: negative regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rh] synonym: "negative regulation of heart muscle cell proliferation" EXACT [] xref: GO:0060044 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0003232 ! regulation of cardiac muscle cell proliferation relationship: has_participant CCO:B0058429 ! TBX5_HUMAN relationship: negatively_regulates CCO:P0003231 ! cardiac muscle cell proliferation [Term] id: CCO:P0003234 name: positive regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rh] synonym: "positive regulation of heart muscle cell proliferation" RELATED [] xref: GO:0060045 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0003232 ! regulation of cardiac muscle cell proliferation relationship: has_participant CCO:B0001583 ! FGF9_HUMAN relationship: has_participant CCO:B0042127 ! BMP10_HUMAN relationship: positively_regulates CCO:P0003231 ! cardiac muscle cell proliferation [Term] id: CCO:P0003235 name: regulation of protein amino acid glycosylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein amino acid glycosylation. Protein amino acid glycosylation is the addition of a sugar unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph] xref: GO:0060049 is_a: CCO:P0001433 ! regulation of protein modification process [Term] id: CCO:P0003236 name: positive regulation of protein amino acid glycosylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein amino acid glycosylation is the addition of a sugar unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph] xref: GO:0060050 is_a: CCO:P0001435 ! positive regulation of protein modification process is_a: CCO:P0003235 ! regulation of protein amino acid glycosylation [Term] id: CCO:P0003237 name: negative regulation of protein amino acid glycosylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein amino acid glycosylation is the addition of a sugar unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:dms, GOC:dph] xref: GO:0060051 is_a: CCO:P0001434 ! negative regulation of protein modification process is_a: CCO:P0003235 ! regulation of protein amino acid glycosylation [Term] id: CCO:P0003238 name: positive regulation of epithelial cell proliferation involved in wound healing namespace: biological_process def: "Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury." [GOC:dph] xref: GO:0060054 is_a: CCO:P0002923 ! positive regulation of epithelial cell proliferation relationship: has_participant CCO:B0055034 ! B4GT1_HUMAN [Term] id: CCO:P0003239 name: positive regulation of apoptosis involved in mammary gland involution namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptosis of mammary epithelial cells during mammary gland involution." [GOC:dph, PMID:15282149] xref: GO:0060058 is_a: CCO:P0002147 ! positive regulation of apoptosis relationship: has_participant CCO:B0055034 ! B4GT1_HUMAN [Term] id: CCO:P0003240 name: Wnt receptor signaling pathway, regulating spindle positioning namespace: biological_process def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle." [GOC:bf, GOC:dph, PMID:11532397] synonym: "non-canonical Wnt signaling pathway" BROAD [] synonym: "Wnt receptor signalling pathway, regulating spindle positioning" EXACT [] xref: GO:0060069 is_a: CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:P0003241 name: Wnt receptor signaling pathway through beta-catenin namespace: biological_process def: "The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes." [GOC:bf, GOC:dph, PMID:11532397] synonym: "canonical Wnt signaling pathway" EXACT [] synonym: "frizzled-1 receptor signaling pathway" NARROW [] synonym: "Wnt receptor signalling pathway through beta-catenin" EXACT [] xref: GO:0060070 is_a: CCO:P0001111 ! Wnt receptor signaling pathway relationship: has_participant CCO:B0001367 ! AXN1_HUMAN relationship: has_participant CCO:B0001556 ! APC_HUMAN relationship: has_participant CCO:B0002152 ! TF7L2_HUMAN relationship: has_participant CCO:B0005327 ! CTNB1_HUMAN relationship: has_participant CCO:B0016826 ! GSK3B_HUMAN relationship: has_participant CCO:B0034126 ! RARG_HUMAN relationship: has_participant CCO:B0054622 ! PROP1_HUMAN [Term] id: CCO:P0003242 name: Wnt receptor signaling pathway, planar cell polarity pathway namespace: biological_process def: "The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity." [GOC:bf, GOC:dph, PMID:11532397] synonym: "Wnt receptor signalling pathway, planar cell polarity pathway" EXACT [] synonym: "Wnt-JNK signaling pathway" RELATED [GOC:bf] synonym: "Wnt-PCP signaling pathway" RELATED [GOC:rh] xref: GO:0060071 is_a: CCO:P0001111 ! Wnt receptor signaling pathway [Term] id: CCO:P0003243 name: regulation of synaptic transmission, glycinergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] xref: GO:0060092 is_a: CCO:P0002958 ! regulation of synaptic transmission [Term] id: CCO:P0003244 name: negative regulation of synaptic transmission, glycinergic namespace: biological_process def: "Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] synonym: "negative regulation of glycinergic synaptic transmission" EXACT [] xref: GO:0060093 is_a: CCO:P0002959 ! negative regulation of synaptic transmission is_a: CCO:P0003243 ! regulation of synaptic transmission, glycinergic [Term] id: CCO:P0003245 name: positive regulation of synaptic transmission, glycinergic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] synonym: "positive regulation of glycinergic synaptic transmission" EXACT [] xref: GO:0060094 is_a: CCO:P0002960 ! positive regulation of synaptic transmission is_a: CCO:P0003243 ! regulation of synaptic transmission, glycinergic [Term] id: CCO:P0003246 name: zinc potentiation of synaptic transmission, glycinergic namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine." [GOC:dms, GOC:dph] synonym: "zinc potentiation of glycinergic synaptic transmission" EXACT [] xref: GO:0060095 is_a: CCO:P0003245 ! positive regulation of synaptic transmission, glycinergic [Term] id: CCO:P0003247 name: regulation of phagocytosis, engulfment namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] xref: GO:0060099 is_a: CCO:P0002942 ! regulation of phagocytosis [Term] id: CCO:P0003248 name: positive regulation of phagocytosis, engulfment namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] xref: GO:0060100 is_a: CCO:P0002944 ! positive regulation of phagocytosis is_a: CCO:P0003247 ! regulation of phagocytosis, engulfment [Term] id: CCO:P0003249 name: negative regulation of phagocytosis, engulfment namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." [GOC:dph] xref: GO:0060101 is_a: CCO:P0002943 ! negative regulation of phagocytosis is_a: CCO:P0003247 ! regulation of phagocytosis, engulfment [Term] id: CCO:P0003250 name: regulation of growth hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell or group of cells." [GOC:dph] xref: GO:0060123 is_a: CCO:P0002744 ! regulation of hormone secretion [Term] id: CCO:P0003251 name: positive regulation of growth hormone secretion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell or group of cells." [GOC:dph] xref: GO:0060124 is_a: CCO:P0002747 ! positive regulation of hormone secretion is_a: CCO:P0003250 ! regulation of growth hormone secretion relationship: has_participant CCO:B0054850 ! SLIB_HUMAN [Term] id: CCO:P0003252 name: negative regulation of growth hormone secretion namespace: biological_process def: "Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell or group of cells." [GOC:dph] xref: GO:0060125 is_a: CCO:P0002748 ! negative regulation of hormone secretion is_a: CCO:P0003250 ! regulation of growth hormone secretion [Term] id: CCO:P0003253 name: positive regulation of apoptosis by virus namespace: biological_process def: "Any viral process that activates or increases the frequency, rate or extent of cell death by apoptosis." [GOC:dph] xref: GO:0060139 is_a: CCO:P0002147 ! positive regulation of apoptosis [Term] id: CCO:P0003254 name: positive regulation of syncitium formation by virus namespace: biological_process def: "The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] xref: GO:0060141 is_a: CCO:P0003256 ! positive regulation of syncytium formation by plasma membrane fusion [Term] id: CCO:P0003255 name: regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] xref: GO:0060142 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0003256 name: positive regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] xref: GO:0060143 is_a: CCO:P0003034 ! positive regulation of cellular component organization and biogenesis is_a: CCO:P0003255 ! regulation of syncytium formation by plasma membrane fusion [Term] id: CCO:P0003257 name: viral gene silencing in virus induced gene silencing namespace: biological_process def: "The posttranscriptional gene silencing of viral genes after viral infection." [GOC:dph] xref: GO:0060145 is_a: CCO:P0001123 ! posttranscriptional gene silencing [Term] id: CCO:P0003258 name: host gene silencing in virus induced gene silencing namespace: biological_process def: "The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection." [GOC:dph] xref: GO:0060146 is_a: CCO:P0001123 ! posttranscriptional gene silencing [Term] id: CCO:P0003259 name: regulation of posttranscriptional gene silencing namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph] xref: GO:0060147 is_a: CCO:P0001142 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process relationship: regulates CCO:P0001123 ! posttranscriptional gene silencing [Term] id: CCO:P0003260 name: positive regulation of posttranscriptional gene silencing namespace: biological_process def: "Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph] xref: GO:0060148 is_a: CCO:P0002620 ! positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0003259 ! regulation of posttranscriptional gene silencing relationship: positively_regulates CCO:P0001123 ! posttranscriptional gene silencing [Term] id: CCO:P0003261 name: negative regulation of posttranscriptional gene silencing namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism." [GOC:dph] xref: GO:0060149 is_a: CCO:P0002619 ! negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process is_a: CCO:P0003259 ! regulation of posttranscriptional gene silencing relationship: negatively_regulates CCO:P0001123 ! posttranscriptional gene silencing [Term] id: CCO:P0003262 name: viral triggering of virus induced gene silencing namespace: biological_process def: "Any process that increases the frequency, rate or extent of the inactivation of gene expression of both viral genes and host homologues to those genes by a posttranscriptional mechanism in a virally infected cell." [GOC:dph] xref: GO:0060150 is_a: CCO:P0003260 ! positive regulation of posttranscriptional gene silencing [Term] id: CCO:P0003263 name: dopamine receptor, phospholipase C activating pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate." [GOC:dph, PMID:12675914] xref: GO:0060158 is_a: CCO:P0000738 ! G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) is_a: CCO:P0000747 ! dopamine receptor signaling pathway relationship: has_participant CCO:B0030251 ! GNA11_HUMAN relationship: has_participant CCO:B0055024 ! DRD2_HUMAN relationship: has_participant CCO:B0055136 ! DRD1_HUMAN [Term] id: CCO:P0003264 name: regulation of dopamine receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph] xref: GO:0060159 is_a: CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: regulates CCO:P0000747 ! dopamine receptor signaling pathway [Term] id: CCO:P0003265 name: negative regulation of dopamine receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph] xref: GO:0060160 is_a: CCO:P0002532 ! negative regulation of G-protein coupled receptor protein signaling pathway is_a: CCO:P0003264 ! regulation of dopamine receptor signaling pathway relationship: negatively_regulates CCO:P0000747 ! dopamine receptor signaling pathway [Term] id: CCO:P0003266 name: positive regulation of dopamine receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." [GOC:dph] xref: GO:0060161 is_a: CCO:P0002533 ! positive regulation of G-protein coupled receptor protein signaling pathway is_a: CCO:P0003264 ! regulation of dopamine receptor signaling pathway relationship: positively_regulates CCO:P0000747 ! dopamine receptor signaling pathway [Term] id: CCO:P0003267 name: negative regulation of dopamine receptor, phospholipase C activating pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway." [GOC:dph, PMID:15016423] xref: GO:0060162 is_a: CCO:P0003265 ! negative regulation of dopamine receptor signaling pathway relationship: negatively_regulates CCO:P0003263 ! dopamine receptor, phospholipase C activating pathway [Term] id: CCO:P0003268 name: regulation of timing of neuron differentiation namespace: biological_process def: "The process controlling the timing and/or rate at which a relatively unspecialized cell acquires features of a neuron." [GOC:dph] xref: GO:0060164 is_a: CCO:P0002478 ! regulation of neuron differentiation is_a: CCO:P0002851 ! regulation of timing of cell differentiation [Term] id: CCO:P0003269 name: regulation of timing of subpallium neuron differentiation namespace: biological_process def: "The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon." [GOC:dph] xref: GO:0060165 is_a: CCO:P0003268 ! regulation of timing of neuron differentiation relationship: has_participant CCO:B0055453 ! ASCL1_HUMAN [Term] id: CCO:P0003270 name: regulation of adenosine receptor signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph] xref: GO:0060167 is_a: CCO:P0000814 ! regulation of G-protein coupled receptor protein signaling pathway relationship: regulates CCO:P0000517 ! adenosine receptor signaling pathway [Term] id: CCO:P0003271 name: positive regulation of adenosine receptor signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph] xref: GO:0060168 is_a: CCO:P0002533 ! positive regulation of G-protein coupled receptor protein signaling pathway is_a: CCO:P0003270 ! regulation of adenosine receptor signaling pathway relationship: positively_regulates CCO:P0000517 ! adenosine receptor signaling pathway [Term] id: CCO:P0003272 name: negative regulation of adenosine receptor signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands." [GOC:dph] xref: GO:0060169 is_a: CCO:P0002532 ! negative regulation of G-protein coupled receptor protein signaling pathway is_a: CCO:P0003270 ! regulation of adenosine receptor signaling pathway relationship: has_participant CCO:B0054829 ! ADA_HUMAN relationship: negatively_regulates CCO:P0000517 ! adenosine receptor signaling pathway [Term] id: CCO:P0003273 name: apelin receptor signaling pathway namespace: biological_process def: "The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands." [GOC:dph] xref: GO:0060183 is_a: CCO:P0000726 ! G-protein coupled receptor protein signaling pathway [Term] id: CCO:P0003274 name: regulation of protein desumoylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process by which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb] xref: GO:0060188 is_a: CCO:P0001433 ! regulation of protein modification process [Term] id: CCO:P0003275 name: positive regulation of protein desumoylation namespace: biological_process def: "Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process by which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb] xref: GO:0060189 is_a: CCO:P0001435 ! positive regulation of protein modification process is_a: CCO:P0003274 ! regulation of protein desumoylation [Term] id: CCO:P0003276 name: negative regulation of protein desumoylation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process by which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein." [GOC:dph, GOC:tb] xref: GO:0060190 is_a: CCO:P0001434 ! negative regulation of protein modification process is_a: CCO:P0003274 ! regulation of protein desumoylation [Term] id: CCO:P0003277 name: regulation of antisense RNA transcription namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:jp, GOC:tb, PMID:18075583] xref: GO:0060194 is_a: CCO:P0000655 ! regulation of transcription, DNA-dependent [Term] id: CCO:P0003278 name: negative regulation of antisense RNA transcription namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:tb, PMID:18075583] xref: GO:0060195 is_a: CCO:P0002595 ! negative regulation of transcription, DNA-dependent is_a: CCO:P0003277 ! regulation of antisense RNA transcription [Term] id: CCO:P0003279 name: positive regulation of antisense RNA transcription namespace: biological_process def: "Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA." [GOC:dph, GOC:tb, PMID:18075583] xref: GO:0060196 is_a: CCO:P0002596 ! positive regulation of transcription, DNA-dependent is_a: CCO:P0003277 ! regulation of antisense RNA transcription [Term] id: CCO:P0003280 name: regulation of nuclear-transcribed mRNA poly(A) tail shortening namespace: biological_process def: "Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb] synonym: "regulation of 3' to 5' mRNA deadenylation" RELATED [] synonym: "regulation of mRNA deadenylation" RELATED [] synonym: "regulation of nuclear mRNA poly(A) tail shortening" RELATED [] xref: GO:0060211 is_a: CCO:P0001410 ! regulation of cellular catabolic process is_a: CCO:P0003068 ! regulation of RNA metabolic process [Term] id: CCO:P0003281 name: negative regulation of nuclear-transcribed mRNA poly(A) tail shortening namespace: biological_process def: "Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb] synonym: "negative regulation of 3' to 5' mRNA deadenylation" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of mRNA deadenylation" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of nuclear mRNA poly(A) tail shortening" RELATED [] xref: GO:0060212 is_a: CCO:P0001411 ! negative regulation of cellular catabolic process is_a: CCO:P0001440 ! negative regulation of mRNA 3'-end processing is_a: CCO:P0003280 ! regulation of nuclear-transcribed mRNA poly(A) tail shortening [Term] id: CCO:P0003282 name: positive regulation of nuclear-transcribed mRNA poly(A) tail shortening namespace: biological_process def: "Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length." [GOC:dph, GOC:tb] synonym: "positive regulation of 3' to 5' mRNA deadenylation" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of mRNA deadenylation" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of nuclear mRNA poly(A) tail shortening" RELATED [] xref: GO:0060213 is_a: CCO:P0001412 ! positive regulation of cellular catabolic process is_a: CCO:P0001441 ! positive regulation of mRNA 3'-end processing is_a: CCO:P0003280 ! regulation of nuclear-transcribed mRNA poly(A) tail shortening [Term] id: CCO:P0003283 name: regulation of retinal cone cell fate commitment namespace: biological_process def: "Any process that modulates the process whereby a cell becomes commited to a retinal cone cell fate. Retinal cone cell fate commitment is the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell." [GOC:dph] xref: GO:0060222 is_a: CCO:P0000940 ! regulation of cell fate commitment [Term] id: CCO:P0003284 name: regulation of retinal rod cell fate commitment namespace: biological_process def: "Any process that modulates the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph] xref: GO:0060224 is_a: CCO:P0000940 ! regulation of cell fate commitment [Term] id: CCO:P0003285 name: positive regulation of retinal rod cell fate commitment namespace: biological_process def: "Any process that increases the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye." [GOC:dph] xref: GO:0060225 is_a: CCO:P0000942 ! positive regulation of cell fate commitment is_a: CCO:P0003284 ! regulation of retinal rod cell fate commitment [Term] id: CCO:P0003286 name: negative regulation of retinal cone cell fate commitment namespace: biological_process def: "Any process that increases the process whereby a cell becomes commited to a retinal cone cell fate. Retinal cone cell fate commitment is the process whereby the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell." [GOC:dph] xref: GO:0060226 is_a: CCO:P0000941 ! negative regulation of cell fate commitment is_a: CCO:P0003283 ! regulation of retinal cone cell fate commitment [Term] id: CCO:P0003287 name: Notch signaling pathway involved in camera-type eye photoreceptor fate commitment namespace: biological_process def: "The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate." [GOC:dph] xref: GO:0060227 is_a: CCO:P0000754 ! Notch signaling pathway [Term] id: CCO:P0003288 name: delamination namespace: biological_process def: "The negative regulation of cell adhesion process by which a cell or sheet of cells splits off of an existing epithelial sheet." [GOC:dph, PMID:16962574, PMID:18343170] xref: GO:0060232 is_a: CCO:P0001238 ! negative regulation of cell-cell adhesion [Term] id: CCO:P0003289 name: oenocyte delamination namespace: biological_process def: "The negative regulation of cell adhesion process by which an oenocyte splits off of an existing epithelial sheet." [GOC:dph] xref: GO:0060233 is_a: CCO:P0003288 ! delamination [Term] id: CCO:P0003290 name: neuroblast delamination namespace: biological_process def: "The negative regulation of cell adhesion process by which a neuroblast slits off of a neurectodermal sheet." [GOC:dph] xref: GO:0060234 is_a: CCO:P0003288 ! delamination [Term] id: CCO:P0003291 name: regulation of fungal-type cell wall organization and biogenesis namespace: biological_process def: "Any process that modulates the rate, frequenct or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall." [GOC:dph, GOC:tb] xref: GO:0060237 is_a: CCO:P0003032 ! regulation of cellular component organization and biogenesis [Term] id: CCO:P0003292 name: regulation of signal transduction during conjugation with cellular fusion namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] xref: GO:0060238 is_a: CCO:P0000884 ! regulation of signal transduction relationship: regulates CCO:P0001521 ! signal transduction during conjugation with cellular fusion [Term] id: CCO:P0003293 name: positive regulation of signal transduction during conjugation with cellular fusion namespace: biological_process def: "Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] xref: GO:0060239 is_a: CCO:P0000885 ! positive regulation of signal transduction is_a: CCO:P0003292 ! regulation of signal transduction during conjugation with cellular fusion relationship: positively_regulates CCO:P0001521 ! signal transduction during conjugation with cellular fusion [Term] id: CCO:P0003294 name: negative regulation of signal transduction during conjugation with cellular fusion namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion." [GOC:dph, GOC:tb] xref: GO:0060240 is_a: CCO:P0000886 ! negative regulation of signal transduction is_a: CCO:P0003292 ! regulation of signal transduction during conjugation with cellular fusion relationship: negatively_regulates CCO:P0001521 ! signal transduction during conjugation with cellular fusion [Term] id: CCO:P0003295 name: negative regulation of cell growth involved in contact inhibition namespace: biological_process def: "The negative regulation of cell growth in response to increased cell density." [GOC:dph] xref: GO:0060243 is_a: CCO:P0001255 ! negative regulation of cell growth [Term] id: CCO:P0003296 name: negative regulation of cell proliferation involved in contact inhibition namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density." [GOC:dph] xref: GO:0060244 is_a: CCO:P0000817 ! negative regulation of cell proliferation [Term] id: CCO:P0003297 name: regulation of glial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb] xref: GO:0060251 is_a: CCO:P0002045 ! regulation of cell proliferation relationship: regulates CCO:P0001056 ! glial cell proliferation [Term] id: CCO:P0003298 name: positive regulation of glial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] xref: GO:0060252 is_a: CCO:P0000816 ! positive regulation of cell proliferation is_a: CCO:P0003297 ! regulation of glial cell proliferation relationship: positively_regulates CCO:P0001056 ! glial cell proliferation [Term] id: CCO:P0003299 name: negative regulation of glial cell proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] xref: GO:0060253 is_a: CCO:P0000817 ! negative regulation of cell proliferation is_a: CCO:P0003297 ! regulation of glial cell proliferation relationship: negatively_regulates CCO:P0001056 ! glial cell proliferation [Term] id: CCO:P0003300 name: negative regulation of N-terminal protein palmitoylation namespace: biological_process def: "Any process that decreases the rate frequency or extent of the covalent or non-covalent attachment of a palmitoyl moiety to the N-terminal amino acid residue of a protein." [GOC:dph, GOC:tb] xref: GO:0060262 is_a: CCO:P0002938 ! negative regulation of lipoprotein metabolic process relationship: has_participant CCO:B0058815 ! HHATL_HUMAN [Term] id: CCO:P0003301 name: photosystem stoichiometry adjustment namespace: biological_process def: "Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis." [PMID:11607105] xref: GO:0080005 is_a: CCO:P0000909 ! regulation of photosynthesis [Term] id: CCO:R0000000 name: biological reference is_a: CCO:U0000001 ! biological continuant [Term] id: CCO:R0000001 name: AgBase def: "AgBase resource for functional analysis of agricultural plant and animal gene products" [] comment: http://www.agbase.msstate.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000002 name: AGI_LocusCode def: "Arabidopsis Genome Initiative (TAIR, TIGR, MIPS)" [] comment: http://www.arabidopsis.org is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000006 name: ApiDB_PlasmoDB def: "PlasmoDB Plasmodium Genome Resource" [] comment: http://plasmodb.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000007 name: AraCyc def: "AraCyc metabolic pathway database for Arabidopsis thaliana" [] comment: http://www.arabidopsis.org/biocyc/index.jsp is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000008 name: BHF-UCL def: "Cardiovascular Gene Ontology Annotation Initiative; supported by the British Heart Foundation (BHF) at University College London (UCL)" [] comment: http://www.cardiovasculargeneontology.com is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000009 name: BIOMD def: "BioModels Database" [] comment: http://www.ebi.ac.uk/biomodels/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000010 name: BIOSIS def: "BIOSIS previews" [] comment: http://www.biosis.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000011 name: BRENDA def: "BRENDA, The Comprehensive Enzyme Information System" [] comment: http://www.brenda.uni-koeln.de/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000012 name: Broad def: "Broad Institute" [] comment: http://www.broad.mit.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000013 name: Broad_MGG def: "Magnaporthe grisea Database at the Broad Institute" [] comment: http://www.broad.mit.edu/annotation/genome/magnaporthe_grisea/Home.html is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000014 name: CBS def: "Center for Biological Sequence Analysis" [] comment: http://www.cbs.dtu.dk/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000015 name: CDD def: "Conserved Domain Database at NCBI" [] comment: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=cdd is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000016 name: CGD def: "Candida Genome Database" [] comment: http://www.candidagenome.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000017 name: CGD_LOCUS def: "Candida Genome Database" [] comment: http://www.candidagenome.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000018 name: CGD_REF def: "Candida Genome Database" [] comment: http://www.candidagenome.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000019 name: CGEN def: "Compugen Gene Ontology Gene Association Data" [] comment: http://www.cgen.com/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000020 name: CGSC def: "CGSC: E.coli Genetic Stock Center" [] comment: http://cgsc.biology.yale.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000021 name: ChEBI def: "Chemical Entities of Biological Interest" [] comment: http://www.ebi.ac.uk/chebi/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000022 name: CL def: "Cell Type Ontology" [] comment: https://lists.sourceforge.net/lists/listinfo/obo-cell-type is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000023 name: COG def: "NCBI Clusters of Orthologous Groups" [] comment: http://www.ncbi.nlm.nih.gov/COG/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000024 name: COG_Cluster def: "NCBI COG cluster" [] comment: http://www.ncbi.nlm.nih.gov/COG/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000025 name: COG_Function def: "NCBI COG function" [] comment: http://www.ncbi.nlm.nih.gov/COG/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000026 name: COG_Pathway def: "NCBI COG pathway" [] comment: http://www.ncbi.nlm.nih.gov/COG/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000030 name: DOI def: "Digital Object Identifier" [] comment: http://dx.doi.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000031 name: EC def: "The Enzyme Commission" [] comment: http://www.chem.qmul.ac.uk/iubmb/enzyme/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000032 name: EchoBASE def: "EchoBASE post-genomic database for Escherichia coli" [] comment: http://www.ecoli-york.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000033 name: ECK def: "The EcoGene Database of Escherichia coli Sequence and Function" [] comment: http://www.ecogene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000034 name: EcoCyc def: "The Encyclopedia of E. coli metabolism" [] comment: http://ecocyc.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000035 name: ECOGENE def: "The EcoGene Database of Escherichia coli Sequence and Function" [] comment: http://www.ecogene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000036 name: ECOGENE_G def: "The EcoGene Database of Escherichia coli Sequence and Function" [] comment: http://www.ecogene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000037 name: EMBL def: "International Nucleotide Sequence Database Collaboration, comprising EMBL-EBI International Nucleotide Sequence Data Library (EMBL-Bank), DNA DataBank of Japan (DDBJ), and NCBI GenBank" [] comment: http://www.ebi.ac.uk/embl/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000038 name: ENSEMBL def: "Database of automatically annotated genomic data" [] comment: http://www.ensembl.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000039 name: ENZYME def: "The Swiss Institute of Bioinformatics database of Enzymes" [] comment: http://www.expasy.ch/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000040 name: FB def: "FlyBase" [] comment: http://flybase.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000042 name: GDB def: "Human Genome Database" [] comment: http://www.gdb.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000043 name: GeneDB_Gmorsitans def: "GeneDB_Gmorsitans" [] comment: http://www.genedb.org/genedb/glossina/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000044 name: GeneDB_Lmajor def: "GeneDB_Lmajor" [] comment: http://www.genedb.org/genedb/leish/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000045 name: GeneDB_Pfalciparum def: "GeneDB_Pfalciparum" [] comment: http://www.genedb.org/genedb/malaria/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000046 name: GeneDB_Spombe def: "GeneDB_Spombe" [] comment: http://www.genedb.org/genedb/pombe/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000047 name: GeneDB_Tbrucei def: "GeneDB_Tbrucei" [] comment: http://www.genedb.org/genedb/tryp/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000048 name: GenProtEC def: "GenProtEC E. coli genome and proteome database" [] comment: http://genprotec.mbl.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000049 name: GermOnline def: "GermOnline" [] comment: http://www.germonline.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000050 name: GO def: "Gene Ontology Database" [] comment: http://amigo.geneontology.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000051 name: GO_REF def: "Gene Ontology Database references" [] comment: http://www.geneontology.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000052 name: GOA def: "GO Annotation at EBI" [] comment: http://www.ebi.ac.uk/goa/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000053 name: GOC def: "Gene Ontology Consortium" [] comment: http://www.geneontology.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000054 name: GR def: "Gramene: A Comparative Mapping Resource for Grains" [] comment: http://www.gramene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000055 name: GR_GENE def: "Gramene: A Comparative Mapping Resource for Grains" [] comment: http://www.gramene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000056 name: GR_PROTEIN def: "Gramene: A Comparative Mapping Resource for Grains" [] comment: http://www.gramene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000057 name: GR_QTL def: "Gramene: A Comparative Mapping Resource for Grains" [] comment: http://www.gramene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000058 name: GR_REF def: "Gramene: A Comparative Mapping Resource for Grains" [] comment: http://www.gramene.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000059 name: H-invDB def: "H-invitational Database" [] comment: http://www.h-invitational.jp/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000060 name: H-invDB_cDNA def: "H-invitational Database" [] comment: http://www.h-invitational.jp/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000061 name: H-invDB_locus def: "H-invitational Database" [] comment: http://www.h-invitational.jp/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000062 name: HAMAP def: "High-quality Automated and Manual Annotation of microbial Proteomes" [] comment: http://us.expasy.org/sprot/hamap/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000063 name: HGNC def: "HUGO Gene Nomenclature Committee" [] comment: http://www.genenames.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000064 name: HGNC_gene def: "HUGO Gene Nomenclature Committee" [] comment: http://www.genenames.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000065 name: HUGO def: "Human Genome Organisation" [] comment: http://www.hugo-international.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000066 name: IMG def: "Integrated Microbial Genomes; JGI web site for genome annotation" [] comment: http://img.jgi.doe.gov is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000067 name: IMGT_HLA def: "Immunogenetics database, human MHC" [] comment: http://www.ebi.ac.uk/imgt/hla is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000068 name: IMGT_LIGM def: "Immunogenetics database, immunoglobulins and T-cell receptors" [] comment: http://imgt.cines.fr is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000069 name: IntAct def: "IntAct protein interaction database" [] comment: http://www.ebi.ac.uk/intact/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000070 name: InterPro def: "The InterPro database of protein domains and motifs" [] comment: http://www.ebi.ac.uk/interpro/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000071 name: IPI def: "International Protein Index" [] comment: http://www.ebi.ac.uk/IPI/IPIhelp.html is_a: CCO:R0000000 ! 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biological reference [Term] id: CCO:R0000187 name: ZFIN def: "The Zebrafish Information Network" [] comment: http://zfin.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000188 name: http is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000189 name: dictyBase def: "dictyBase" [] comment: http://dictybase.org is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000190 name: dictyBase_gene_name def: "dictyBase" [] comment: http://dictybase.org is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000191 name: dictyBase_REF def: "dictyBase literature references" [] comment: http://dictybase.org is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000192 name: Gene3D def: "Domain Architecture Classification" [] comment: http://gene3d.biochem.ucl.ac.uk/Gene3D/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000193 name: SUPERFAMILY def: "SUPERFAMILY. A database of structural and functional protein annotations for completely sequenced genomes" [] comment: http://supfam.mrc-lmb.cam.ac.uk/SUPERFAMILY/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000194 name: CASGEN def: "Catalog of Fishes genus database" [] comment: http://research.calacademy.org/research/ichthyology/catalog/fishcatsearch.html is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000195 name: CASSPC def: "Catalog of Fishes species database" [] comment: http://research.calacademy.org/research/ichthyology/catalog/fishcatsearch.html is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000196 name: SGN def: "Sol Genomics Network" [] comment: http://www.sgn.cornell.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000197 name: EcoliWiki def: "EcoliWiki, EcoliHub's subsystem for community annotation of E. coli K-12" [] comment: http://ecoliwiki.net/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000198 name: SGN_ref def: "Sol Genomics Network" [] comment: http://www.sgn.cornell.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000199 name: UM-BBD_reactionID def: "The University of Minnesota Biocatalysis/Biodegradation Database" [] comment: http://umbbd.msi.umn.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000200 name: UM-BBD_ruleID def: "The University of Minnesota Biocatalysis/Biodegradation Database" [] comment: http://umbbd.msi.umn.edu/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000201 name: AGRICOLA_ID def: "AGRICultural OnLine Access" [] comment: http://agricola.nal.usda.gov/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000202 name: bioPIXIE_MEFIT def: "biological Process Inference from eXperimental Interaction Evidence/Microarray Experiment Functional Integration Technology" [] comment: http://pixie.princeton.edu/pixie/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000203 name: EcoCyc_REF def: "The Encyclopedia of E. coli metabolism" [] comment: http://ecocyc.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000204 name: DDBJ def: "International Nucleotide Sequence Database Collaboration, comprising EMBL-EBI International Nucleotide Sequence Data Library (EMBL-Bank), DNA DataBank of Japan (DDBJ), and NCBI GenBank" [] comment: http://www.ddbj.nig.ac.jp/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000205 name: GenBank def: "International Nucleotide Sequence Database Collaboration, comprising EMBL-EBI International Nucleotide Sequence Data Library (EMBL-Bank), DNA DataBank of Japan (DDBJ), and NCBI GenBank" [] comment: http://www.ncbi.nlm.nih.gov/Genbank/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000206 name: IUPHAR_GPCR def: "The International Union of Pharmacology" [] comment: http://www.iuphar.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000207 name: IUPHAR_RECEPTOR def: "The International Union of Pharmacology" [] comment: http://www.iuphar.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000208 name: JCVI def: "The J. Craig Venter Institute" [] comment: http://www.jcvi.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000209 name: JCVI_Ath1 def: "The J. Craig Venter Institute, Arabidopsis thaliana database" [] comment: http://www.tigr.org/tdb/e2k1/ath1/ath1.shtml is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000210 name: JCVI_CMR def: "The J. Craig Venter Institute, Comprehensive Microbial Resource" [] comment: http://cmr.jcvi.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000211 name: JCVI_EGAD def: "The J. Craig Venter Institute, EGAD database" [] comment: http://cmr.jcvi.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000212 name: JCVI_GenProp def: "The J. Craig Venter Institute, Genome Properties" [] comment: http://cmr.jcvi.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000213 name: JCVI_Pfa1 def: "The J. Craig Venter Institute, Plasmodium falciparum database" [] comment: http://www.tigr.org/tdb/e2k1/pfa1/pfa1.shtml is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000214 name: JCVI_REF def: "The J. Craig Venter Institute" [] comment: http://cmr.jcvi.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000215 name: JCVI_Tba1 def: "The J. Craig Venter Institute, Trypanosoma brucei database" [] comment: http://www.tigr.org/tdb/e2k1/tba1/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000216 name: JCVI_TIGRFAMS def: "The J. Craig Venter Institute, TIGRFAMs HMM collection" [] comment: http://cmr.jcvi.org/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000217 name: KEGG_LIGAND def: "KEGG LIGAND Database" [] comment: http://www.genome.ad.jp/kegg/docs/upd_ligand.html is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000218 name: RefSeq def: "RefSeq" [] comment: http://www.ncbi.nlm.nih.gov/RefSeq/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000219 name: VBRC def: "Viral Bioinformatics Resource Center" [] comment: http://vbrc.org is_a: CCO:R0000000 ! biological reference [Term] id: CCO:R0000220 name: YeastFunc def: "Yeast Function" [] comment: http://func.med.harvard.edu/yeast/ is_a: CCO:R0000000 ! biological reference [Term] id: CCO:T0000001 name: Tetrapoda organism xref: NCBI:32523 is_a: CCO:T0000051 ! Sarcopterygii organism [Term] id: CCO:T0000002 name: Ascomycota organism xref: NCBI:4890 is_a: CCO:T0000024 ! Dikarya organism [Term] id: CCO:T0000003 name: Theria organism xref: NCBI:32525 is_a: CCO:T0000057 ! Mammalia organism [Term] id: CCO:T0000004 name: Homo sapiens organism xref: NCBI:9606 is_a: CCO:T0000054 ! Homo organism [Term] id: CCO:T0000005 name: Coelomata organism xref: NCBI:33316 is_a: CCO:T0000036 ! Bilateria organism [Term] id: CCO:T0000006 name: Euteleostomi organism xref: NCBI:117571 is_a: CCO:T0000027 ! Teleostomi organism [Term] id: CCO:T0000007 name: rosids organism xref: NCBI:71275 is_a: CCO:T0000038 ! core eudicotyledons organism [Term] id: CCO:T0000008 name: Schizosaccharomyces organism xref: NCBI:4895 is_a: CCO:T0000056 ! Schizosaccharomycetaceae organism [Term] id: CCO:T0000009 name: Streptophyta organism xref: NCBI:35493 is_a: CCO:T0000012 ! Viridiplantae organism [Term] id: CCO:T0000010 name: Magnoliophyta organism xref: NCBI:3398 is_a: CCO:T0000032 ! Spermatophyta organism [Term] id: CCO:T0000011 name: organism xref: NCBI:1 is_a: CCO:U0000001 ! biological continuant [Term] id: CCO:T0000012 name: Viridiplantae organism xref: NCBI:33090 is_a: CCO:T0000033 ! Eukaryota organism [Term] id: CCO:T0000013 name: Schizosaccharomycetales organism xref: NCBI:34346 is_a: CCO:T0000025 ! Schizosaccharomycetes organism [Term] id: CCO:T0000014 name: Saccharomycetales organism xref: NCBI:4892 is_a: CCO:T0000040 ! Saccharomycetes organism [Term] id: CCO:T0000015 name: eudicotyledons organism xref: NCBI:71240 is_a: CCO:T0000010 ! Magnoliophyta organism [Term] id: CCO:T0000016 name: Saccharomyces cerevisiae organism xref: NCBI:4932 is_a: CCO:T0000019 ! Saccharomyces organism [Term] id: CCO:T0000017 name: Schizosaccharomyces pombe organism xref: NCBI:4896 is_a: CCO:T0000008 ! Schizosaccharomyces organism [Term] id: CCO:T0000018 name: Euphyllophyta organism xref: NCBI:78536 is_a: CCO:T0000031 ! Tracheophyta organism [Term] id: CCO:T0000019 name: Saccharomyces organism xref: NCBI:4930 is_a: CCO:T0000035 ! Saccharomycetaceae organism [Term] id: CCO:T0000020 name: Metazoa organism xref: NCBI:33208 is_a: CCO:T0000042 ! Fungi/Metazoa group organism [Term] id: CCO:T0000021 name: Homo/Pan/Gorilla group organism xref: NCBI:207598 is_a: CCO:T0000060 ! Hominidae organism [Term] id: CCO:T0000022 name: Brassicales organism xref: NCBI:3699 is_a: CCO:T0000062 ! eurosids II organism [Term] id: CCO:T0000023 name: Embryophyta organism xref: NCBI:3193 is_a: CCO:T0000053 ! Streptophytina organism [Term] id: CCO:T0000024 name: Dikarya organism xref: NCBI:451864 is_a: CCO:T0000026 ! Fungi organism [Term] id: CCO:T0000025 name: Schizosaccharomycetes organism xref: NCBI:147554 is_a: CCO:T0000052 ! Taphrinomycotina organism [Term] id: CCO:T0000026 name: Fungi organism xref: NCBI:4751 is_a: CCO:T0000042 ! Fungi/Metazoa group organism [Term] id: CCO:T0000027 name: Teleostomi organism xref: NCBI:117570 is_a: CCO:T0000050 ! Gnathostomata organism [Term] id: CCO:T0000028 name: Brassicaceae organism xref: NCBI:3700 is_a: CCO:T0000022 ! Brassicales organism [Term] id: CCO:T0000029 name: Primates organism xref: NCBI:9443 is_a: CCO:T0000055 ! Euarchontoglires organism [Term] id: CCO:T0000030 name: Hominoidea organism xref: NCBI:314295 is_a: CCO:T0000047 ! Catarrhini organism [Term] id: CCO:T0000031 name: Tracheophyta organism xref: NCBI:58023 is_a: CCO:T0000023 ! Embryophyta organism [Term] id: CCO:T0000032 name: Spermatophyta organism xref: NCBI:58024 is_a: CCO:T0000018 ! Euphyllophyta organism [Term] id: CCO:T0000033 name: Eukaryota organism xref: NCBI:2759 is_a: CCO:T0000041 ! cellular organisms organism [Term] id: CCO:T0000034 name: Arabidopsis thaliana organism xref: NCBI:3702 is_a: CCO:T0000059 ! Arabidopsis organism [Term] id: CCO:T0000035 name: Saccharomycetaceae organism xref: NCBI:4893 is_a: CCO:T0000014 ! Saccharomycetales organism [Term] id: CCO:T0000036 name: Bilateria organism xref: NCBI:33213 is_a: CCO:T0000049 ! Eumetazoa organism [Term] id: CCO:T0000037 name: Vertebrata organism xref: NCBI:7742 is_a: CCO:T0000045 ! Craniata organism [Term] id: CCO:T0000038 name: core eudicotyledons organism xref: NCBI:91827 is_a: CCO:T0000015 ! eudicotyledons organism [Term] id: CCO:T0000039 name: Saccharomycotina organism xref: NCBI:147537 is_a: CCO:T0000002 ! Ascomycota organism [Term] id: CCO:T0000040 name: Saccharomycetes organism xref: NCBI:4891 is_a: CCO:T0000039 ! Saccharomycotina organism [Term] id: CCO:T0000041 name: cellular organisms organism xref: NCBI:131567 is_a: CCO:T0000011 ! organism [Term] id: CCO:T0000042 name: Fungi/Metazoa group organism xref: NCBI:33154 is_a: CCO:T0000033 ! Eukaryota organism [Term] id: CCO:T0000043 name: Amniota organism xref: NCBI:32524 is_a: CCO:T0000001 ! Tetrapoda organism [Term] id: CCO:T0000044 name: Deuterostomia organism xref: NCBI:33511 is_a: CCO:T0000005 ! Coelomata organism [Term] id: CCO:T0000045 name: Craniata organism xref: NCBI:89593 is_a: CCO:T0000046 ! Chordata organism [Term] id: CCO:T0000046 name: Chordata organism xref: NCBI:7711 is_a: CCO:T0000044 ! Deuterostomia organism [Term] id: CCO:T0000047 name: Catarrhini organism xref: NCBI:9526 is_a: CCO:T0000048 ! Simiiformes organism [Term] id: CCO:T0000048 name: Simiiformes organism xref: NCBI:314293 is_a: CCO:T0000061 ! Haplorrhini organism [Term] id: CCO:T0000049 name: Eumetazoa organism xref: NCBI:6072 is_a: CCO:T0000020 ! Metazoa organism [Term] id: CCO:T0000050 name: Gnathostomata organism xref: NCBI:7776 is_a: CCO:T0000037 ! Vertebrata organism [Term] id: CCO:T0000051 name: Sarcopterygii organism xref: NCBI:8287 is_a: CCO:T0000006 ! Euteleostomi organism [Term] id: CCO:T0000052 name: Taphrinomycotina organism xref: NCBI:451866 is_a: CCO:T0000002 ! Ascomycota organism [Term] id: CCO:T0000053 name: Streptophytina organism xref: NCBI:131221 is_a: CCO:T0000009 ! Streptophyta organism [Term] id: CCO:T0000054 name: Homo organism xref: NCBI:9605 is_a: CCO:T0000021 ! Homo/Pan/Gorilla group organism [Term] id: CCO:T0000055 name: Euarchontoglires organism xref: NCBI:314146 is_a: CCO:T0000058 ! Eutheria organism [Term] id: CCO:T0000056 name: Schizosaccharomycetaceae organism xref: NCBI:4894 is_a: CCO:T0000013 ! Schizosaccharomycetales organism [Term] id: CCO:T0000057 name: Mammalia organism xref: NCBI:40674 is_a: CCO:T0000043 ! Amniota organism [Term] id: CCO:T0000058 name: Eutheria organism xref: NCBI:9347 is_a: CCO:T0000003 ! Theria organism [Term] id: CCO:T0000059 name: Arabidopsis organism xref: NCBI:3701 is_a: CCO:T0000028 ! Brassicaceae organism [Term] id: CCO:T0000060 name: Hominidae organism xref: NCBI:9604 is_a: CCO:T0000030 ! Hominoidea organism [Term] id: CCO:T0000061 name: Haplorrhini organism xref: NCBI:376913 is_a: CCO:T0000029 ! Primates organism [Term] id: CCO:T0000062 name: eurosids II organism xref: NCBI:91836 is_a: CCO:T0000007 ! rosids organism [Term] id: CCO:U0000000 name: biological entity def: "A biological process or continuant." [CCO:ea] synonym: "biological-entity" EXACT [CCO:ea] [Term] id: CCO:U0000001 name: biological continuant def: "Biological entities which endure, or continue to exist, through time while undergoing different sort of changes, including changes of place." [CCO:ea, PMID:15892874] synonym: "biological endurant" EXACT [PMID:15892874] synonym: "biological thing" BROAD [PMID:15892874] is_a: CCO:U0000000 ! biological entity [Term] id: CCO:U0000002 name: biological process def: "Biological entities that unfold themselves in successive temporal phases." [CCO:ea, PMID:15892874] synonym: "biological ocurrent" BROAD [PMID:15892874] synonym: "biological perdurant" EXACT [PMID:15892874] is_a: CCO:U0000000 ! biological entity disjoint_from: CCO:U0000001 [Term] id: CCO:U0000003 name: gene product def: "A gene product, such as a protein, or transcript, ocurring in, or formed by, living systems." [CCO:ea] is_a: CCO:U0000001 ! biological continuant [Term] id: CCO:U0000004 name: gene def: "Each of the units of heredity which (except for polygenes) may be regarded as the controlling agents in the expression of single phenotypic characters and are usually segments of a chromosome at fixed positions relative to each other." [CCO:ea, http://www.oed.com] is_a: CCO:U0000001 ! biological continuant [Term] id: CCO:U0000005 name: protein def: "Proteins are polymeric macromolecules composed of one or more long chains of amino acids linked by peptide bonds, usually coiled and folded into complex globular or fibrous structures." [CCO:ea, http://www.oed.com] is_a: CCO:U0000003 ! gene product [Term] id: CCO:U0000006 name: cell cycle continuant def: "Cell cycle entities which endure, or continue to exist, through time while undergoing different sort of changes, including changes of place." [CCO:ea] is_a: CCO:U0000001 ! biological continuant [Term] id: CCO:U0000007 name: cell cycle protein def: "Cell cycle proteins are polymeric macromolecules composed of one or more long chains of amino acids linked by peptide bonds, usually coiled and folded into complex globular or fibrous structures." [CCO:ea] is_a: CCO:U0000005 ! protein is_a: CCO:U0000006 ! cell cycle continuant [Term] id: CCO:U0000008 name: cell cycle gene def: "Cell cycle units of heredity which (except for polygenes) may be regarded as the controlling agents in the expression of single phenotypic characters and are usually segments of a chromosome at fixed positions relative to each other." [CCO:ea] is_a: CCO:U0000004 ! gene is_a: CCO:U0000006 ! cell cycle continuant [Term] id: CCO:U0000009 name: small molecule def: "A small structural unit of matter consisting of one or more atoms." [CCO:ea] is_a: CCO:U0000001 ! biological continuant [Term] id: CCO:U0000010 name: modified protein def: "A protein which underwent any sort of modification (e.g. phosphorylation)" [CCO:ea] is_a: CCO:U0000005 ! protein [Term] id: CCO:U0000011 name: cell cycle modified protein def: "A cell cycle protein which underwent any sort of modification (e.g. phosphorylation)" [CCO:ea] is_a: CCO:U0000007 ! cell cycle protein is_a: CCO:U0000010 ! modified protein [Term] id: CCO:Y0000001 name: interaction type def: "Connection between molecule." [PMID:14755292] subset: PSI-MI slim xref: MI:0190 is_a: CCO:U0000002 ! biological process [Term] id: CCO:Y0000002 name: acetylation reaction def: "Reaction, that can affect K,C,A,D,E,Q,G,I,K,M,P,S,T,Y,V residues." [GO:0006473, PMID:14755292, RESID:AA0041, RESID:AA0042, RESID:AA0043, RESID:AA0044, RESID:AA0045, RESID:AA0046, RESID:AA0047, RESID:AA0048, RESID:AA0049, RESID:AA0050, RESID:AA0051, RESID:AA0052, RESID:AA0053, RESID:AA0054, RESID:AA0055, RESID:AA0056] subset: PSI-MI slim synonym: "acetylation" EXACT PSI-MI-short [] xref: MI:0192 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000003 name: amidation reaction def: "Irreversible reaction that can affect A,R,N,D,C,Q,E,G,H,I,L,K,M,F,P,S,T,W,Y or V residues." [GO:0001519, PMID:14755292, RESID:AA0081, RESID:AA0082, RESID:AA0083, RESID:AA0084, RESID:AA0085, RESID:AA0086, RESID:AA0087, RESID:AA0088, RESID:AA0089, RESID:AA0090, RESID:AA0091, RESID:AA0092, RESID:AA0093, RESID:AA0094, RESID:AA0095, RESID:AA0096, RESID:AA0097, RESID:AA0098, RESID:AA0099, RESID:AA0100] subset: PSI-MI slim synonym: "amidation" EXACT PSI-MI-short [] xref: MI:0193 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000004 name: cleavage reaction def: "Covalent bond breakage in a molecule leading to the formation of smaller molecules." [PMID:14755292] subset: PSI-MI slim synonym: "cleavage" EXACT PSI-MI-short [] xref: MI:0194 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000005 name: covalent binding def: "Interaction leading to the formation of covalent bond within an autocatalytic molecule or between partners." [PMID:14755292] subset: PSI-MI slim xref: MI:0195 is_a: CCO:Y0000028 ! direct interaction [Term] id: CCO:Y0000006 name: deacetylation reaction def: "N6-acetyl-L-lysine or S-acetyl-L-cysteine are cleaved and return K or C residues." [GO:0006476, PMID:14755292, RESID:AA0055, RESID:AA0056] subset: PSI-MI slim synonym: "deacetylation" EXACT PSI-MI-short [] xref: MI:0197 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000007 name: defarnesylation reaction def: "S-farnesyl-L-cysteined is cleaved and returns a C residue." [PMID:14755292, RESID:AA0102] subset: PSI-MI slim synonym: "defarnesylation" EXACT PSI-MI-short [] xref: MI:0198 is_a: CCO:Y0000020 ! lipid cleavage [Term] id: CCO:Y0000008 name: deformylation reaction def: "N6-formyl-L-lysine is cleaved and returns a K residue." [PMID:14755292, RESID:AA0211] subset: PSI-MI slim synonym: "deformylation" EXACT PSI-MI-short [] xref: MI:0199 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000009 name: degeranylation reaction def: "S-geranylgeranyl-L-cysteine is cleaved and returns a C residue." [PMID:14755292, RESID:AA0104] subset: PSI-MI slim synonym: "degeranylation" EXACT PSI-MI-short [] xref: MI:0200 is_a: CCO:Y0000020 ! lipid cleavage [Term] id: CCO:Y0000010 name: demyristoylation reaction def: "N6-myristoyl-L-lysine is cleaved and returns a K residue." [PMID:14755292, RESID:AA0078] subset: PSI-MI slim synonym: "demyristoylation" EXACT PSI-MI-short [] xref: MI:0201 is_a: CCO:Y0000020 ! lipid cleavage [Term] id: CCO:Y0000011 name: depalmitoylation reaction def: "S-palmitoyl-L-cysteine, N6-palmitoyl-L-lysine, O-palmitoyl-L-threonine or O-palmitoyl-L-serine are cleaved and return C,K,T or S residues." [PMID:14755292, RESID:AA0060, RESID:AA0077, RESID:AA0106] subset: PSI-MI slim synonym: "depalmitoylation" EXACT PSI-MI-short [] xref: MI:0202 is_a: CCO:Y0000020 ! lipid cleavage [Term] id: CCO:Y0000012 name: dephosphorylation reaction def: "Phosphoresidues are cleaved and return D,C,H,S,T,Y or R residues." [GO:0016311, PMID:14755292, RESID:AA0033, RESID:AA0034, RESID:AA0035, RESID:AA0036, RESID:AA0037, RESID:AA0038, RESID:AA0039, RESID:AA0222] subset: PSI-MI slim synonym: "dephosphorylation" EXACT PSI-MI-short [] xref: MI:0203 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000013 name: deubiquitination reaction def: "Cleavage of the G-K bond and release of ubiquitin or ubiquitin like proteins." [GO:0016579, PMID:11583613, RESID:AA0125] subset: PSI-MI slim synonym: "deubiquitination" EXACT PSI-MI-short [] xref: MI:0204 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000014 name: farnesylation reaction def: "Reversible reaction that can affect C residue." [GO:0018347, PMID:14755292, RESID:AA0102] subset: PSI-MI slim synonym: "farnesylation" EXACT PSI-MI-short [] xref: MI:0206 is_a: CCO:Y0000019 ! lipid addition [Term] id: CCO:Y0000015 name: formylation reaction def: "Reaction that can affect K or G residues." [GO:0018256, PMID:14755292, RESID:AA0057, RESID:AA0211] subset: PSI-MI slim synonym: "formylation" EXACT PSI-MI-short [] xref: MI:0207 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000016 name: genetic interaction def: "Two genes A and B \"genetically interact\" when the phenotype generated as the result of mutations in both genes (double mutant ab) is unexpectedly not just a combination of the phenotypes of the two single mutants a and b." [PMID:16527956] subset: PSI-MI slim xref: MI:0208 is_a: CCO:Y0000001 ! interaction type [Term] id: CCO:Y0000017 name: geranylgeranylation reaction def: "Reversible reaction that can affect C residue." [GO:0018348, PMID:14755292, RESID:AA0104] subset: PSI-MI slim synonym: "geranylgeranylation" EXACT PSI-MI-short [] xref: MI:0209 is_a: CCO:Y0000019 ! lipid addition [Term] id: CCO:Y0000018 name: hydroxylation reaction def: "Irreversible reaction that can affect K,P,Y or R residues." [GO:0018126, PMID:14755292, RESID:AA0028, RESID:AA0029, RESID:AA0030, RESID:AA0146, RESID:AA0215] subset: PSI-MI slim synonym: "hydroxylation" EXACT PSI-MI-short [] xref: MI:0210 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000019 name: lipid addition def: "Covalent or non covalent binding of lipid group on a protein residue." [GO:0006497, PMID:14755292] subset: PSI-MI slim xref: MI:0211 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000020 name: lipid cleavage def: "Cleavage of a lipid group covalently bound to a protein residue." [PMID:14755292] subset: PSI-MI slim xref: MI:0212 is_a: CCO:Y0000004 ! cleavage reaction [Term] id: CCO:Y0000021 name: methylation reaction def: "The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer. Irreversible reaction that can affect A,G,M,F,P,C,R,N,Q,E,H,or K residues." [GO:0043414, PMID:14755292, RESID:AA0061, RESID:AA0062, RESID:AA0063, RESID:AA0064, RESID:AA0065, RESID:AA0066, RESID:AA0067, RESID:AA0068, RESID:AA0069, RESID:AA0070, RESID:AA0071, RESID:AA0072, RESID:AA0073, RESID:AA0074, RESID:AA0075, RESID:AA0076, RESID:AA0234, RESID:AA0272] subset: PSI-MI slim synonym: "methylation" EXACT PSI-MI-short [] xref: MI:0213 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000022 name: myristoylation reaction def: "Reaction that can affect K or G residues." [GO:0018319, PMID:14755292, RESID:AA0059, RESID:AA0078] subset: PSI-MI slim synonym: "myristoylation" EXACT PSI-MI-short [] xref: MI:0214 is_a: CCO:Y0000019 ! lipid addition [Term] id: CCO:Y0000023 name: palmitoylation reaction def: "Reversible reaction that can affect C,K,T or S residues." [GO:0018318, PMID:14755292, RESID:AA0060, RESID:AA0077, RESID:AA0079, RESID:AA0080, RESID:AA0106] subset: PSI-MI slim synonym: "palmitoylation" EXACT PSI-MI-short [] xref: MI:0216 is_a: CCO:Y0000019 ! lipid addition [Term] id: CCO:Y0000024 name: phosphorylation reaction def: "Reversible reaction that can affect D,C,H,S,T,Y,R residues." [GO:0016310, PMID:14755292, RESID:AA0033, RESID:AA0034, RESID:AA0035, RESID:AA0036, RESID:AA0037, RESID:AA0038, RESID:AA0039, RESID:AA0222] subset: PSI-MI slim synonym: "phosphorylation" EXACT PSI-MI-short [] xref: MI:0217 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000026 name: ubiquitination reaction def: "Reversible reaction that create a covalent bond between a C-terminus G of ubiquitin and a K residue of the target." [GO:0016567, PMID:11583613, RESID:AA0125] subset: PSI-MI slim synonym: "ubiquitination" EXACT PSI-MI-short [] xref: MI:0220 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000027 name: colocalization def: "Coincident occurrence of molecules in a given subcellular fraction observed with a low resolution methodology from which a physical interaction among those molecules cannot be inferred." [PMID:14755292] subset: PSI-MI slim xref: MI:0403 is_a: CCO:Y0000001 ! interaction type [Term] id: CCO:Y0000028 name: direct interaction def: "Interaction that is proven to involve only its interactors." [PMID:14755292] subset: PSI-MI slim xref: MI:0407 is_a: CCO:Y0000060 ! physical association [Term] id: CCO:Y0000029 name: disulfide bond def: "Covalent bond mediated by 2 sulfur atoms." [PMID:14755292] subset: PSI-MI slim xref: MI:0408 is_a: CCO:Y0000005 ! covalent binding [Term] id: CCO:Y0000030 name: enzymatic reaction def: "terms aiming to represent biochemical reactions referring to their resulting product modifications." [PMID:14755292] subset: PSI-MI slim synonym: "Biochemical reaction" EXACT PSI-MI-alternate [] xref: MI:0414 is_a: CCO:Y0000028 ! direct interaction [Term] id: CCO:Y0000031 name: transglutamination reaction def: "Gln-Lys cross-link catalyzed by a transglutaminase." [PMID:14755292, RESID:AA0124] subset: PSI-MI slim synonym: "transglutamination" EXACT PSI-MI-short [] xref: MI:0556 is_a: CCO:Y0000005 ! covalent binding [Term] id: CCO:Y0000032 name: adp ribosylation reaction def: "Reaction that can affect Arg, Cys, Glu, Arg and Asn residues." [GO:0006471, PMID:14755292, RESID:AA0168, RESID:AA0169, RESID:AA0231, RESID:AA0237, RESID:AA0295] subset: PSI-MI slim synonym: "adp ribosylation" EXACT PSI-MI-short [] xref: MI:0557 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000033 name: deglycosylation reaction def: "Reaction catalyzed by PNGase, a deglycosylating enzyme that promotes the hydrolysis of the beta-aspartylglycosylamine bond of aspargine-linked glycopeptides and glycoproteins." [GO:0006517, PMID:15670854] subset: PSI-MI slim synonym: "deglycosylation" EXACT PSI-MI-short [] xref: MI:0558 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000034 name: glycosylation reaction def: "The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer. Reaction that can affect Ser, Thr, Cys, Arg, and Asn residues. This reaction is known to be reversible in the case of Asn substrate." [GO:0043413, PMID:14755292, RESID:AA0122, RESID:AA0151, RESID:AA0154, RESID:AA0155, RESID:AA0327] subset: PSI-MI slim synonym: "glycosylation" EXACT PSI-MI-short [] xref: MI:0559 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000035 name: sumoylation reaction def: "Reversible reaction that create a covalent bond between a C-terminus G of an ubiquitine like sumo protein and a K residue of the target." [GO:0016925, PMID:15985640] subset: PSI-MI slim synonym: "sumoylation" EXACT PSI-MI-short [] xref: MI:0566 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000036 name: neddylation reaction def: "Reversible reaction that create a covalent bond between a Glycine residue of an ubiquitine like NEDD8 protein and a lysine residue of the target." [GO:0045116, PMID:16127432] subset: PSI-MI slim synonym: "neddylation" EXACT PSI-MI-short [] xref: MI:0567 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000037 name: desumoylation reaction def: "Cleavage of the G-K bond and release of the SUMO ubiquitin like proteins." [GO:0016926, PMID:15985640] subset: PSI-MI slim synonym: "desumoylation" EXACT PSI-MI-short [] xref: MI:0568 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000038 name: deneddylation reaction def: "Cleavage of the G-K bond and release of the NEDD8 ubiquitin like proteins. Deneddylation, which removes the NEDD8 moiety, requires the isopeptidase activity of the COP9 signalosome." [GO:0000338, PMID:16127432] subset: PSI-MI slim synonym: "deneddylation" EXACT PSI-MI-short [] xref: MI:0569 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000039 name: protein cleavage def: "Covalent modification of a polypeptide occuring during its maturation or its proteolytic degradation." [PMID:14744292] subset: PSI-MI slim xref: MI:0570 is_a: CCO:Y0000004 ! cleavage reaction [Term] id: CCO:Y0000040 name: mrna cleavage def: "Any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner." [GO:0006379, PMID:14681407] subset: PSI-MI slim xref: MI:0571 is_a: CCO:Y0000057 ! rna cleavage [Term] id: CCO:Y0000041 name: dna cleavage def: "Covalent bond breakage of a DNA molecule leading to the formation of smaller fragments." [PMID:14755292] subset: PSI-MI slim xref: MI:0572 is_a: CCO:Y0000058 ! nucleic acid cleavage [Term] id: CCO:Y0000042 name: dna strand elongation def: "The process by which a DNA strand is synthesized from template DNA by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand." [GO:0006271, PMID:14755292] subset: PSI-MI slim synonym: "DNA replication elongation " EXACT PSI-MI-alternate [] synonym: "elongation" EXACT PSI-MI-short [] xref: MI:0701 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000052 name: phosphotransfer reaction def: "Reaction where a phosphate is transferred between two proteins of a phosphorelay system. " [PMID:14755292, PMID:16712436] subset: PSI-MI slim synonym: "phosphotransfer" EXACT PSI-MI-short [] xref: MI:0844 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000053 name: demethylation reaction def: "The cleavage of a methyl group from a polypeptide. Methylation is generally an irreversible reaction except in mamalian." [GO:0006482, PMID:17277772] subset: PSI-MI slim synonym: "demethylation" EXACT PSI-MI-short [] xref: MI:0871 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000054 name: nucleoside triphosphatase reaction def: "Catalysis of the hydrolisis of a nucleoside triphosphate into a nucleoside diphosphate plus phosphate." [GO:0017111, PMID:14755292] subset: PSI-MI slim synonym: "triphosphatase react" EXACT PSI-MI-short [] xref: MI:0881 is_a: CCO:Y0000030 ! enzymatic reaction [Term] id: CCO:Y0000055 name: atpase reaction def: "Catalysis of the hydrolisis of ATP+ H2O = ADP + phosphate." [GO:0016887, PMID:14755292] subset: PSI-MI slim xref: MI:0882 is_a: CCO:Y0000054 ! nucleoside triphosphatase reaction [Term] id: CCO:Y0000056 name: gtpase reaction def: "Catalysis of the hydrolisis of GTP+ H2O = GDP + phosphate." [GO:0003924, PMID:14755292] subset: PSI-MI slim xref: MI:0883 is_a: CCO:Y0000054 ! nucleoside triphosphatase reaction [Term] id: CCO:Y0000057 name: rna cleavage def: "Any process by which an RNA molecule is cleaved at specific sites or in a regulated manner." [GO:0006396, PMID:14681407] subset: PSI-MI slim xref: MI:0902 is_a: CCO:Y0000058 ! nucleic acid cleavage [Term] id: CCO:Y0000058 name: nucleic acid cleavage def: "Covalent bond breakage of a nucleic acid molecule leading to the formation of smaller fragments." [PMID:14755292] subset: PSI-MI slim synonym: "ncl acid cleavage" EXACT PSI-MI-short [] xref: MI:0910 is_a: CCO:Y0000004 ! cleavage reaction [Term] id: CCO:Y0000059 name: association def: "Molecules that are experimentally shown to be associated potentially by sharing just one interactor. Often associated molecules are co-purified by a pull-down or coimmunoprecipitation and share the same bait molecule." [PMID:14755292] subset: PSI-MI slim xref: MI:0914 is_a: CCO:Y0000001 ! interaction type [Term] id: CCO:Y0000060 name: physical association def: "Molecules that are experimentally shown to belong to the same functional or structural complex." [PMID:14755292] subset: PSI-MI slim xref: MI:0915 is_a: CCO:Y0000059 ! association [Term] id: CCO:Y0000061 name: synthetic genetic interaction defined by inequality def: "The phenotype resulting from genetic perturbation a and the phenotype resulting from genetic perturbation b have no effect on the WT background, but the combined genetic perturbation of A and B has a phenotypic effect. E. g., WT = a = b > ab." [PMID:15833125] subset: PSI-MI slim synonym: "synthetic" EXACT PSI-MI-short [] synonym: "synthetic genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0794 is_a: CCO:Y0000070 ! genetic interaction defined by inequality is_a: CCO:Y0000072 ! negative genetic interaction [Term] id: CCO:Y0000062 name: asynthetic genetic interaction defined by inequality def: "The phenotype resulting from genetic perturbation of A alone, B alone and AB combined have the same effect on the WT background. E. g., WT > a = b = ab." [PMID:15833125] subset: PSI-MI slim synonym: "asynthetic" EXACT PSI-MI-short [] synonym: "asynthetic genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0795 is_a: CCO:Y0000069 ! epistatic genetic interaction is_a: CCO:Y0000070 ! genetic interaction defined by inequality [Term] id: CCO:Y0000063 name: suppressive genetic interaction defined by inequality def: "The phenotype resulting from genetic perturbation of A has an effect on WT, but that effect is abolished by adding the suppressor b, which itself shows no single-mutant effect. E. g., WT = b = ab > a." [PMID:15833125] subset: PSI-MI slim synonym: "suppression" EXACT PSI-MI-short [] synonym: "suppressive genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0796 is_a: CCO:Y0000069 ! epistatic genetic interaction is_a: CCO:Y0000070 ! genetic interaction defined by inequality [Term] id: CCO:Y0000064 name: epistatic genetic interaction defined by inequality def: "The phenotype resulting from genetic perturbation of A and B have different effects (in terms of direction or magnitude) on the wild-type background and the double mutant has the same phenotype as either A or B (for example, A < WT < B = AB)." [PMID:15833125] subset: PSI-MI slim synonym: "epistatic" EXACT PSI-MI-short [] synonym: "epistatic genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0797 is_a: CCO:Y0000069 ! epistatic genetic interaction is_a: CCO:Y0000070 ! genetic interaction defined by inequality [Term] id: CCO:Y0000065 name: conditional genetic interaction defined by inequality def: "The phenotype resulting from genetic perturbation of A has an effect only in the b background, or the b mutant has an effect only in the a background. a has an effect only in the b background, or the b mutant has an effect only in the a background. E. g., WT = a > ab > b or WT > a > b > ab." [PMID:15833125] subset: PSI-MI slim synonym: "conditional" EXACT PSI-MI-short [] synonym: "conditional genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0798 is_a: CCO:Y0000070 ! genetic interaction defined by inequality [Term] id: CCO:Y0000066 name: additive genetic interaction defined by inequality def: "Single-mutant phenotype effects combine to give a double-mutant effect different from the wild type and different from single mutant effect. For instance, WT < a = b < ab, b < WT = ab < a, WT < a < b < ab, b < WT < ab < a, and all additional inequalities obtained by interchanging a and b, or reversing the effect of both a and b." [PMID:15833125] subset: PSI-MI slim synonym: "additive" EXACT PSI-MI-short [] synonym: "additive genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0799 is_a: CCO:Y0000070 ! genetic interaction defined by inequality [Term] id: CCO:Y0000067 name: single nonmonotonic genetic interaction defined by inequality def: "The phenotype resulting from genetic perturbation of B shows opposing effects in the WT and a backgrounds (for example, b > WT and ab < a); or, a shows opposing effects in the WT and b backgrounds, but not both. E.g., WT > a > ab > b." [PMID:15833125] subset: PSI-MI slim synonym: "single nonmonotonic" EXACT PSI-MI-short [] synonym: "single nonmonotonic genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0800 is_a: CCO:Y0000070 ! genetic interaction defined by inequality [Term] id: CCO:Y0000068 name: double nonmonotonic genetic interaction defined by inequality def: "The phenotype resulting from genetic perturbation of both A and B show opposing effects in the WT background and the background with the other mutant gene. E.g., WT >= ab > a >= b" [PMID:15833125] subset: PSI-MI slim synonym: "double nonmonotonic" EXACT PSI-MI-short [] synonym: "double nonmonotonic genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0801 is_a: CCO:Y0000070 ! genetic interaction defined by inequality is_a: CCO:Y0000074 ! positive genetic interaction [Term] id: CCO:Y0000069 name: epistatic genetic interaction def: "The genetic interaction between a group of genes, in which the effects of an allele of one member gene of the group hide the effects of alleles of other genes in the group." [PMID:11988766] subset: PSI-MI slim synonym: "epistatis" EXACT PSI-MI-short [] xref: MI:0930 is_a: CCO:Y0000074 ! positive genetic interaction [Term] id: CCO:Y0000070 name: genetic interaction defined by inequality def: "Two genes A and B present an genetic interaction defined by inequality if the phenotypes of the two single mutants a and b, the double mutant ab and the wild-type WT can be measured quantitatively and described relative to each other by an inequality relationship." [PMID:14755292] subset: PSI-MI slim synonym: "genetic inequality" EXACT PSI-MI-short [] xref: MI:0931 is_a: CCO:Y0000016 ! genetic interaction [Term] id: CCO:Y0000071 name: noninteractive genetic interaction defined by inequality def: "Mutation that has no effect in the WT and b backgrounds, or b has no effect in the a and WT backgrounds, or both hold true. E. g., WT = a > b = ab." [PMID:15833125] subset: PSI-MI slim synonym: "noninteractive" EXACT PSI-MI-short [] synonym: "noninteractive genetic interaction (sensu inequality)" EXACT PSI-MI-alternate [] xref: MI:0932 is_a: CCO:Y0000070 ! genetic interaction defined by inequality is_a: CCO:Y0000073 ! neutral genetic interaction [Term] id: CCO:Y0000072 name: negative genetic interaction def: "The phenotype of the double mutant ab is stronger than expected from the combination of the individual effects of a and b." [PMID:14755292] subset: PSI-MI slim synonym: "negative gen int" EXACT PSI-MI-short [] xref: MI:0933 is_a: CCO:Y0000016 ! genetic interaction [Term] id: CCO:Y0000073 name: neutral genetic interaction def: "The phenotype of the double mutant ab is equal to the phenotype expected from the combination of the individual effects of a and b." [PMID:14755292] subset: PSI-MI slim synonym: "neutral gent int" EXACT PSI-MI-short [] xref: MI:0934 is_a: CCO:Y0000016 ! genetic interaction [Term] id: CCO:Y0000074 name: positive genetic interaction def: "The phenotype of the double mutant ab is weaker than expected from the combination of the individual effects of a and b." [PMID:14755292] subset: PSI-MI slim synonym: "positive gent int" EXACT PSI-MI-short [] xref: MI:0935 is_a: CCO:Y0000016 ! genetic interaction [Typedef] id: adjacent_to name: adjacent_to def: "C adjacent to C' if and only if: given any instance c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c and c' are in spatial proximity" [PMID:15892874] comment: Note that adjacent_to as thus defined is not a symmetric relation, in contrast to its instance-level counterpart. For it can be the case that Cs are in general such as to be adjacent to instances of C1 while no analogous statement holds for C1s in general in relation to instances of C. Examples are: nuclear membrane adjacent_to cytoplasm; seminal vesicle adjacent_to urinary bladder; ovary adjacent_to parietal pelvic peritoneum xref: OBO_REL:adjacent_to is_a: relationship ! relationship [Typedef] id: agent_in name: agent_in xref: OBO_REL:agent_in is_a: participates_in ! participates_in [Typedef] id: association name: association def: "C in association with C' produces C'' if and only if for all c belonging to C and c' belongin to C', exists a c'' (belonging to C'') which is the result of the reversible union between c and c'." [CCO:ea] comment: Ternary relationship. See http://www.w3.org/TR/swbp-n-aryRelations/ for the OWL equivalent. The dissociation is a reversible splitting into simpler entities. xref: CCO_REL:association is_a: relationship ! relationship [Typedef] id: catalyses name: catalyses def: "C catalyses P if and only if for all c (catalyst) belonging to C, exists a p (belonging to P) which chemical reaction rate is increased by c." [CCO:ea] comment: C inhibits P if and only if for all c (inhibitor) belonging to C, exists a p (belonging to P) which chemical reaction rate is reduced or prevented by c. synonym: "activates" EXACT [] xref: CCO_REL:catalyses is_a: relationship ! relationship [Typedef] id: codes_for name: codes_for def: "g encodes for p where g a Gene and p is a Protein." [CCO:ea] synonym: "encodes" EXACT [CCO:ea] xref: CCO_REL:codes_for is_a: relationship ! relationship [Typedef] id: contained_in name: contained_in def: "C contained_in C' if and only if: given any instance c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c located_in c' at t, and it is not the case that c *overlaps* c' at t. (c' is a conduit or cavity.)" [PMID:15892874] comment: Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition): xref: OBO_REL:contained_in is_a: relationship ! relationship [Typedef] id: contains name: contains xref: OBO_REL:contains is_a: relationship ! relationship [Typedef] id: degradates name: degradates def: "C is degradated (into NIL) if and only if for all c belonging to C, exists c', c'', ... (belonging to C', C'', ...) which are the result of any undesired breakdown of c with impairment or loss of its characteristic properties." [CCO:ea] comment: NIL entity must be created. synonym: "decomposition" EXACT [] synonym: "catabolism" EXACT [] xref: CCO_REL:degradates is_a: relationship ! relationship [Typedef] id: derived_into name: derived_into xref: OBO_REL:derived_into is_transitive: true is_a: relationship ! relationship [Typedef] id: derives_from name: derives_from def: "Derivation on the instance level (*derives_from*) holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. We say that one class C derives_from class C' if instances of C are connected to instances of C' via some chain of instance-level derivation relations. Example: osteocyte derives_from osteoblast. Formally: C derives_immediately_from C' if and only if: given any c and any t, if c instantiates C at time t, then there is some c' and some t', such that c' instantiates C' at t' and t' earlier-than t and c *derives_from* c'. C derives_from C' if and only if: there is an chain of immediate derivation relations connecting C to C'." [PMID:15892874] comment: Derivation as a relation between instances. The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant. synonym: "derived_from" EXACT [] xref: OBO_REL:derives_from is_transitive: true is_a: relationship ! relationship [Typedef] id: encoded_by name: encoded_by def: "p is encoded by g where p is a Protein and g a Gene." [CCO:ea] synonym: "is_produced_by" EXACT [CCO:ea] synonym: "coded_by" EXACT [CCO:ea] xref: CCO_REL:encoded_by is_a: relationship ! relationship [Typedef] id: has_agent name: has_agent def: "As for has_participant, but with the additional condition that the component instance is causally active in the relevant process" [PMID:15892874] xref: OBO_REL:has_agent is_a: has_participant ! has_participant [Typedef] id: has_function name: has_function def: "P has_function F where P is a protein and F a molecular function" [CCO:ea] xref: CCO_REL:has_function is_a: relationship ! relationship [Typedef] id: has_improper_part name: has_improper_part comment: See reasons for obsoletion of improper_part_of xref: OBO_REL:has_improper_part is_reflexive: true is_transitive: true is_a: has_part ! has_part is_obsolete: true [Typedef] id: has_integral_part name: has_integral_part xref: OBO_REL:has_integral_part is_anti_symmetric: true is_reflexive: true is_transitive: true is_a: has_part ! has_part [Typedef] id: has_part name: has_part xref: OBO_REL:has_part is_anti_symmetric: true is_reflexive: true is_transitive: true is_a: relationship ! relationship [Typedef] id: has_participant name: has_participant def: "P has_participant C if and only if: given any process p that instantiates P there is some continuant c, and some time t, such that: c instantiates C at t and c participates in p at t" [PMID:15892874] comment: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time. xref: OBO_REL:has_participant is_a: relationship ! relationship [Typedef] id: has_proper_part name: has_proper_part xref: OBO_REL:has_proper_part is_transitive: true is_a: has_part ! has_part [Typedef] id: has_source name: has_source def: "o has_source O where o is a gene or gene product and O an organism." [CCO:ea] xref: CCO_REL:has_source is_a: relationship ! relationship [Typedef] id: improper_part_of name: improper_part_of def: "As for part_of, with the additional constraint that subject and object may be identical" [PMID:15892874] comment: OBSOLETE. The definition is "As for part_of, with the additional constraint that subject and object may be identical". However, part_of is already reflexive, therefore improper_part_of is identical to part_of. If read differently, as "improper_part_of is part_of but not proper_part_of",improper_part_of becomes identity. So, improper_part_of is either identical to part_of or to identity, and not an intuitive synonym for either of them. [Robert Hoehndorf] xref: OBO_REL:improper_part_of is_reflexive: true is_transitive: true is_a: part_of ! part_of is_obsolete: true [Typedef] id: instance_of name: instance_of builtin: true def: "A relation between an instance and a class. For components: a primitive relation between a component instance and a class which it instantiates at a specific time. For processes: a primitive relation, between a process instance and a class which it instantiates, holding independently of time" [PMID:15892874] comment: The instance_of relationship is considered axiomatic by the obo file format specification; ie it is taken for granted. The is_a relation is still included in this ontology for completeness xref: OBO_REL:instance_of is_a: relationship ! relationship [Typedef] id: integral_part_of name: integral_part_of def: "C integral_part_of C' if and only if: C part_of C' AND C' has_part C" [PMID:15892874] xref: OBO_REL:integral_part_of is_anti_symmetric: true is_reflexive: true is_transitive: true is_a: part_of ! part_of [Typedef] id: interacts_with name: interacts_with def: "C interacts_with C' if and only if for all c belonging to C, exists a c' (belonging to C') which plays a role with c'." [CCO:ea] xref: CCO_REL:interacts_with is_symmetric: true is_transitive: true is_a: relationship ! relationship [Typedef] id: is_a name: is_a [Typedef] id: located_in name: located_in def: "C located_in C' if and only if: given any c that instantiates C at a time t, there is some c' such that: c' instantiates C' at time t and c *located_in* c'. (Here *located_in* is the instance-level location relation.)" [PMID:15892874] comment: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus xref: OBO_REL:located_in is_reflexive: true is_transitive: true is_a: relationship ! relationship [Typedef] id: location_of name: location_of xref: OBO_REL:location_of is_reflexive: true is_transitive: true is_a: relationship ! relationship [Typedef] id: negatively_regulates name: negatively_regulates [Typedef] id: part_of name: part_of xref: OBO_REL:part_of is_transitive: true [Typedef] id: participates_in name: participates_in def: "C participates_in P if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in xref: OBO_REL:participates_in is_a: relationship ! relationship [Typedef] id: participates_in(IC) name: participates_in(IC) def: "C participates_in P (Inferred by Curator) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IC) is_a: participates_in ! participates_in [Typedef] id: participates_in(IDA) name: participates_in(IDA) def: "C participates_in P (Inferred from Direct Assay) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IDA) is_a: participates_in ! participates_in [Typedef] id: participates_in(IEA) name: participates_in(IEA) def: "C participates_in P (Inferred from Electronic Annotation) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IEA) is_a: participates_in ! participates_in [Typedef] id: participates_in(IEP) name: participates_in(IEP) def: "C participates_in P (Inferred from Expression Pattern) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IEP) is_a: participates_in ! participates_in [Typedef] id: participates_in(IGC) name: participates_in(IGC) def: "C participates_in P (Inferred from Genomic Context) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IGC) is_a: participates_in ! participates_in [Typedef] id: participates_in(IGI) name: participates_in(IGI) def: "C participates_in P (Inferred from Genetic Interaction) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IGI) is_a: participates_in ! participates_in [Typedef] id: participates_in(IMP) name: participates_in(IMP) def: "C participates_in P (Inferred from Mutant Phenotype) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IMP) is_a: participates_in ! participates_in [Typedef] id: participates_in(IPI) name: participates_in(IPI) def: "C participates_in P (Inferred from Physical Interaction) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(IPI) is_a: participates_in ! participates_in [Typedef] id: participates_in(ISS) name: participates_in(ISS) def: "C participates_in P (Inferred from Sequence or Structural Similarity) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(ISS) is_a: participates_in ! participates_in [Typedef] id: participates_in(NAS) name: participates_in(NAS) def: "C participates_in P (Non-traceable Author Statement) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(NAS) is_a: participates_in ! participates_in [Typedef] id: participates_in(ND) name: participates_in(ND) def: "C participates_in P (No biological Data available) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(ND) is_a: participates_in ! participates_in [Typedef] id: participates_in(NR) name: participates_in(NR) def: "C participates_in P (Not Recorded) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(NR) is_a: participates_in ! participates_in is_obsolete: true [Typedef] id: participates_in(RCA) name: participates_in(RCA) def: "C participates_in P (inferred from Reviewed Computational Analysis) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(RCA) is_a: participates_in ! participates_in [Typedef] id: participates_in(TAS) name: participates_in(TAS) def: "C participates_in P (Traceable Author Statement) if and only if: given any continuant c that instantiates C there is some process p, and some time t, such that: p has part c at t" [CCO:ea] xref: CCO_REL:participates_in(TAS) is_a: participates_in ! participates_in [Typedef] id: positively_regulates name: positively_regulates [Typedef] id: preceded_by name: preceded_by def: "P preceded_by P' if and only if: given any process p that instantiates P at a time t, there is some process p' such that p' instantiates P' at time t', and t' is earlier than t. " [PMID:15892874] comment: An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other. xref: OBO_REL:preceded_by is_transitive: true is_a: relationship ! relationship [Typedef] id: precedes name: precedes xref: OBO_REL:precedes is_transitive: true is_a: relationship ! relationship [Typedef] id: proper_part_of name: proper_part_of def: "As for part_of, with the additional constraint that subject and object are distinct" [PMID:15892874] xref: OBO_REL:proper_part_of is_transitive: true is_a: part_of ! part_of [Typedef] id: regulates name: regulates [Typedef] id: relationship name: relationship def: "A relationship between two classes (terms). Relationships between classes are expressed in terms of relations on underlying instances." [] xref: OBO_REL:relationship [Typedef] id: source_of name: source_of def: "O is source_of o where O is an organism and o a gene or gene product." [CCO:ea] xref: CCO_REL:source_of is_a: relationship ! relationship [Typedef] id: transformation_of name: transformation_of def: "Relation between two classes, in which instances retain their identity yet change their classification by virtue of some kind of transformation. Formally: C transformation_of C' if and only if given any c and any t, if c instantiates C at time t, then for some t', c instantiates C' at t' and t' earlier t, and there is no t2 such that c instantiates C at t2 and c instantiates C' at t2." [PMID:15892874] comment: When an embryonic oenocyte (a type of insect cell) is transformed into a larval oenocyte, one and the same continuant entity preserves its identity while instantiating distinct classes at distinct times. The class-level relation transformation_of obtains between continuant classes C and C1 wherever each instance of the class C is such as to have existed at some earlier time as an instance of the distinct class C1 (see Figure 2 in paper). This relation is illustrated first of all at the molecular level of granularity by the relation between mature RNA and the pre-RNA from which it is processed, or between (UV-induced) thymine-dimer and thymine dinucleotide. At coarser levels of granularity it is illustrated by the transformations involved in the creation of red blood cells, for example, from reticulocyte to erythrocyte, and by processes of development, for example, from larva to pupa, or from (post-gastrular) embryo to fetus or from child to adult. It is also manifest in pathological transformations, for example, of normal colon into carcinomatous colon. In each such case, one and the same continuant entity instantiates distinct classes at different times in virtue of phenotypic changes. xref: OBO_REL:transformation_of is_transitive: true is_a: relationship ! relationship [Typedef] id: transforms_into name: transforms_into xref: CCO_REL:transforms_into is_transitive: true is_a: relationship ! relationship